data_9JJ1
# 
_entry.id   9JJ1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JJ1         pdb_00009jj1 10.2210/pdb9jj1/pdb 
WWPDB D_1300051437 ?            ?                   
EMDB  EMD-61514    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-04 ? 
2 'EM metadata'     1 0 2025-06-04 ? 
3 'Half map'        1 0 2025-06-04 1 
4 'Half map'        1 0 2025-06-04 2 
5 Image             1 0 2025-06-04 ? 
6 'Primary map'     1 0 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JJ1 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human ZnT3' 
_pdbx_database_related.db_id          EMD-61514 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              umeji@mol.f.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Umeharu 
_pdbx_contact_author.name_last          Ohto 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4422-4044 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ishida, H.'  1 ? 
'Yo, R.'      2 ? 
'Zhnag, Z.'   3 ? 
'Shimizu, T.' 4 ? 
'Ohto, U.'    5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural basis for the zinc transporters, ZnT3 and ZnT4' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ishida, H.'  1 ? 
primary 'Yo, R.'      2 ? 
primary 'Zhang, Z.'   3 ? 
primary 'Shimizu, T.' 4 ? 
primary 'Ohto, U.'    5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Probable proton-coupled zinc antiporter SLC30A3' 43927.316 2 ? ? ? ? 
2 non-polymer syn 'ZINC ION'                                        65.409    6 ? ? ? ? 
3 non-polymer syn 'Lauryl Maltose Neopentyl Glycol'                 1005.188  2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 30 member 3,Zinc transporter 3,ZnT-3' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQAGSIEGRIVKDYK
DDDDK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQAGSIEGRIVKDYK
DDDDK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION'                        ZN  
3 'Lauryl Maltose Neopentyl Glycol' AV0 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   PRO n 
1 4   SER n 
1 5   PRO n 
1 6   ALA n 
1 7   ALA n 
1 8   GLY n 
1 9   GLY n 
1 10  LEU n 
1 11  GLU n 
1 12  THR n 
1 13  THR n 
1 14  ARG n 
1 15  LEU n 
1 16  VAL n 
1 17  SER n 
1 18  PRO n 
1 19  ARG n 
1 20  ASP n 
1 21  ARG n 
1 22  GLY n 
1 23  GLY n 
1 24  ALA n 
1 25  GLY n 
1 26  GLY n 
1 27  SER n 
1 28  LEU n 
1 29  ARG n 
1 30  LEU n 
1 31  LYS n 
1 32  SER n 
1 33  LEU n 
1 34  PHE n 
1 35  THR n 
1 36  GLU n 
1 37  PRO n 
1 38  SER n 
1 39  GLU n 
1 40  PRO n 
1 41  LEU n 
1 42  PRO n 
1 43  GLU n 
1 44  GLU n 
1 45  SER n 
1 46  LYS n 
1 47  PRO n 
1 48  VAL n 
1 49  GLU n 
1 50  MET n 
1 51  PRO n 
1 52  PHE n 
1 53  HIS n 
1 54  HIS n 
1 55  CYS n 
1 56  HIS n 
1 57  ARG n 
1 58  ASP n 
1 59  PRO n 
1 60  LEU n 
1 61  PRO n 
1 62  PRO n 
1 63  PRO n 
1 64  GLY n 
1 65  LEU n 
1 66  THR n 
1 67  PRO n 
1 68  GLU n 
1 69  ARG n 
1 70  LEU n 
1 71  HIS n 
1 72  ALA n 
1 73  ARG n 
1 74  ARG n 
1 75  GLN n 
1 76  LEU n 
1 77  TYR n 
1 78  ALA n 
1 79  ALA n 
1 80  CYS n 
1 81  ALA n 
1 82  VAL n 
1 83  CYS n 
1 84  PHE n 
1 85  VAL n 
1 86  PHE n 
1 87  MET n 
1 88  ALA n 
1 89  GLY n 
1 90  GLU n 
1 91  VAL n 
1 92  VAL n 
1 93  GLY n 
1 94  GLY n 
1 95  TYR n 
1 96  LEU n 
1 97  ALA n 
1 98  HIS n 
1 99  SER n 
1 100 LEU n 
1 101 ALA n 
1 102 ILE n 
1 103 MET n 
1 104 THR n 
1 105 ASP n 
1 106 ALA n 
1 107 ALA n 
1 108 HIS n 
1 109 LEU n 
1 110 LEU n 
1 111 ALA n 
1 112 ASP n 
1 113 VAL n 
1 114 GLY n 
1 115 SER n 
1 116 MET n 
1 117 MET n 
1 118 GLY n 
1 119 SER n 
1 120 LEU n 
1 121 PHE n 
1 122 SER n 
1 123 LEU n 
1 124 TRP n 
1 125 LEU n 
1 126 SER n 
1 127 THR n 
1 128 ARG n 
1 129 PRO n 
1 130 ALA n 
1 131 THR n 
1 132 ARG n 
1 133 THR n 
1 134 MET n 
1 135 THR n 
1 136 PHE n 
1 137 GLY n 
1 138 TRP n 
1 139 HIS n 
1 140 ARG n 
1 141 SER n 
1 142 GLU n 
1 143 THR n 
1 144 LEU n 
1 145 GLY n 
1 146 ALA n 
1 147 LEU n 
1 148 ALA n 
1 149 SER n 
1 150 VAL n 
1 151 VAL n 
1 152 SER n 
1 153 LEU n 
1 154 TRP n 
1 155 MET n 
1 156 VAL n 
1 157 THR n 
1 158 GLY n 
1 159 ILE n 
1 160 LEU n 
1 161 LEU n 
1 162 TYR n 
1 163 LEU n 
1 164 ALA n 
1 165 PHE n 
1 166 VAL n 
1 167 ARG n 
1 168 LEU n 
1 169 LEU n 
1 170 HIS n 
1 171 SER n 
1 172 ASP n 
1 173 TYR n 
1 174 HIS n 
1 175 ILE n 
1 176 GLU n 
1 177 GLY n 
1 178 GLY n 
1 179 ALA n 
1 180 MET n 
1 181 LEU n 
1 182 LEU n 
1 183 THR n 
1 184 ALA n 
1 185 SER n 
1 186 ILE n 
1 187 ALA n 
1 188 VAL n 
1 189 CYS n 
1 190 ALA n 
1 191 ASN n 
1 192 LEU n 
1 193 LEU n 
1 194 MET n 
1 195 ALA n 
1 196 PHE n 
1 197 VAL n 
1 198 LEU n 
1 199 HIS n 
1 200 GLN n 
1 201 ALA n 
1 202 GLY n 
1 203 PRO n 
1 204 PRO n 
1 205 HIS n 
1 206 SER n 
1 207 HIS n 
1 208 GLY n 
1 209 SER n 
1 210 ARG n 
1 211 GLY n 
1 212 ALA n 
1 213 GLU n 
1 214 TYR n 
1 215 ALA n 
1 216 PRO n 
1 217 LEU n 
1 218 GLU n 
1 219 GLU n 
1 220 GLY n 
1 221 PRO n 
1 222 GLU n 
1 223 GLU n 
1 224 PRO n 
1 225 LEU n 
1 226 PRO n 
1 227 LEU n 
1 228 GLY n 
1 229 ASN n 
1 230 THR n 
1 231 SER n 
1 232 VAL n 
1 233 ARG n 
1 234 ALA n 
1 235 ALA n 
1 236 PHE n 
1 237 VAL n 
1 238 HIS n 
1 239 VAL n 
1 240 LEU n 
1 241 GLY n 
1 242 ASP n 
1 243 LEU n 
1 244 LEU n 
1 245 GLN n 
1 246 SER n 
1 247 PHE n 
1 248 GLY n 
1 249 VAL n 
1 250 LEU n 
1 251 ALA n 
1 252 ALA n 
1 253 SER n 
1 254 ILE n 
1 255 LEU n 
1 256 ILE n 
1 257 TYR n 
1 258 PHE n 
1 259 LYS n 
1 260 PRO n 
1 261 GLN n 
1 262 TYR n 
1 263 LYS n 
1 264 ALA n 
1 265 ALA n 
1 266 ASP n 
1 267 PRO n 
1 268 ILE n 
1 269 SER n 
1 270 THR n 
1 271 PHE n 
1 272 LEU n 
1 273 PHE n 
1 274 SER n 
1 275 ILE n 
1 276 CYS n 
1 277 ALA n 
1 278 LEU n 
1 279 GLY n 
1 280 SER n 
1 281 THR n 
1 282 ALA n 
1 283 PRO n 
1 284 THR n 
1 285 LEU n 
1 286 ARG n 
1 287 ASP n 
1 288 VAL n 
1 289 LEU n 
1 290 ARG n 
1 291 ILE n 
1 292 LEU n 
1 293 MET n 
1 294 GLU n 
1 295 GLY n 
1 296 THR n 
1 297 PRO n 
1 298 ARG n 
1 299 ASN n 
1 300 VAL n 
1 301 GLY n 
1 302 PHE n 
1 303 GLU n 
1 304 PRO n 
1 305 VAL n 
1 306 ARG n 
1 307 ASP n 
1 308 THR n 
1 309 LEU n 
1 310 LEU n 
1 311 SER n 
1 312 VAL n 
1 313 PRO n 
1 314 GLY n 
1 315 VAL n 
1 316 ARG n 
1 317 ALA n 
1 318 THR n 
1 319 HIS n 
1 320 GLU n 
1 321 LEU n 
1 322 HIS n 
1 323 LEU n 
1 324 TRP n 
1 325 ALA n 
1 326 LEU n 
1 327 THR n 
1 328 LEU n 
1 329 THR n 
1 330 TYR n 
1 331 HIS n 
1 332 VAL n 
1 333 ALA n 
1 334 SER n 
1 335 ALA n 
1 336 HIS n 
1 337 LEU n 
1 338 ALA n 
1 339 ILE n 
1 340 ASP n 
1 341 SER n 
1 342 THR n 
1 343 ALA n 
1 344 ASP n 
1 345 PRO n 
1 346 GLU n 
1 347 ALA n 
1 348 VAL n 
1 349 LEU n 
1 350 ALA n 
1 351 GLU n 
1 352 ALA n 
1 353 SER n 
1 354 SER n 
1 355 ARG n 
1 356 LEU n 
1 357 TYR n 
1 358 SER n 
1 359 ARG n 
1 360 PHE n 
1 361 GLY n 
1 362 PHE n 
1 363 SER n 
1 364 SER n 
1 365 CYS n 
1 366 THR n 
1 367 LEU n 
1 368 GLN n 
1 369 VAL n 
1 370 GLU n 
1 371 GLN n 
1 372 TYR n 
1 373 GLN n 
1 374 PRO n 
1 375 GLU n 
1 376 MET n 
1 377 ALA n 
1 378 GLN n 
1 379 CYS n 
1 380 LEU n 
1 381 ARG n 
1 382 CYS n 
1 383 GLN n 
1 384 GLU n 
1 385 PRO n 
1 386 PRO n 
1 387 GLN n 
1 388 ALA n 
1 389 GLY n 
1 390 SER n 
1 391 ILE n 
1 392 GLU n 
1 393 GLY n 
1 394 ARG n 
1 395 ILE n 
1 396 VAL n 
1 397 LYS n 
1 398 ASP n 
1 399 TYR n 
1 400 LYS n 
1 401 ASP n 
1 402 ASP n 
1 403 ASP n 
1 404 ASP n 
1 405 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   405 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC30A3, ZNT3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            expi293F 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ? 'C3 H7 N O2'     89.093   
ARG 'L-peptide linking' y ARGININE                          ? 'C6 H15 N4 O2 1' 175.209  
ASN 'L-peptide linking' y ASPARAGINE                        ? 'C4 H8 N2 O3'    132.118  
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ? 'C4 H7 N O4'     133.103  
AV0 non-polymer         . 'Lauryl Maltose Neopentyl Glycol' 
;2,2-didecylpropane-1,3-bis-b-D-maltopyranoside; 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
;
'C47 H88 O22'    1005.188 
CYS 'L-peptide linking' y CYSTEINE                          ? 'C3 H7 N O2 S'   121.158  
GLN 'L-peptide linking' y GLUTAMINE                         ? 'C5 H10 N2 O3'   146.144  
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ? 'C5 H9 N O4'     147.129  
GLY 'peptide linking'   y GLYCINE                           ? 'C2 H5 N O2'     75.067   
HIS 'L-peptide linking' y HISTIDINE                         ? 'C6 H10 N3 O2 1' 156.162  
ILE 'L-peptide linking' y ISOLEUCINE                        ? 'C6 H13 N O2'    131.173  
LEU 'L-peptide linking' y LEUCINE                           ? 'C6 H13 N O2'    131.173  
LYS 'L-peptide linking' y LYSINE                            ? 'C6 H15 N2 O2 1' 147.195  
MET 'L-peptide linking' y METHIONINE                        ? 'C5 H11 N O2 S'  149.211  
PHE 'L-peptide linking' y PHENYLALANINE                     ? 'C9 H11 N O2'    165.189  
PRO 'L-peptide linking' y PROLINE                           ? 'C5 H9 N O2'     115.130  
SER 'L-peptide linking' y SERINE                            ? 'C3 H7 N O3'     105.093  
THR 'L-peptide linking' y THREONINE                         ? 'C4 H9 N O3'     119.119  
TRP 'L-peptide linking' y TRYPTOPHAN                        ? 'C11 H12 N2 O2'  204.225  
TYR 'L-peptide linking' y TYROSINE                          ? 'C9 H11 N O3'    181.189  
VAL 'L-peptide linking' y VALINE                            ? 'C5 H11 N O2'    117.146  
ZN  non-polymer         . 'ZINC ION'                        ? 'Zn 2'           65.409   
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   PRO 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   ALA 7   7   ?   ?   ?   A . n 
A 1 8   GLY 8   8   ?   ?   ?   A . n 
A 1 9   GLY 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  GLU 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  THR 13  13  ?   ?   ?   A . n 
A 1 14  ARG 14  14  ?   ?   ?   A . n 
A 1 15  LEU 15  15  ?   ?   ?   A . n 
A 1 16  VAL 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  PRO 18  18  ?   ?   ?   A . n 
A 1 19  ARG 19  19  ?   ?   ?   A . n 
A 1 20  ASP 20  20  ?   ?   ?   A . n 
A 1 21  ARG 21  21  ?   ?   ?   A . n 
A 1 22  GLY 22  22  ?   ?   ?   A . n 
A 1 23  GLY 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  GLY 25  25  ?   ?   ?   A . n 
A 1 26  GLY 26  26  ?   ?   ?   A . n 
A 1 27  SER 27  27  ?   ?   ?   A . n 
A 1 28  LEU 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  ?   ?   ?   A . n 
A 1 30  LEU 30  30  ?   ?   ?   A . n 
A 1 31  LYS 31  31  ?   ?   ?   A . n 
A 1 32  SER 32  32  ?   ?   ?   A . n 
A 1 33  LEU 33  33  ?   ?   ?   A . n 
A 1 34  PHE 34  34  ?   ?   ?   A . n 
A 1 35  THR 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  PRO 37  37  ?   ?   ?   A . n 
A 1 38  SER 38  38  ?   ?   ?   A . n 
A 1 39  GLU 39  39  ?   ?   ?   A . n 
A 1 40  PRO 40  40  ?   ?   ?   A . n 
A 1 41  LEU 41  41  ?   ?   ?   A . n 
A 1 42  PRO 42  42  ?   ?   ?   A . n 
A 1 43  GLU 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  SER 45  45  ?   ?   ?   A . n 
A 1 46  LYS 46  46  ?   ?   ?   A . n 
A 1 47  PRO 47  47  ?   ?   ?   A . n 
A 1 48  VAL 48  48  ?   ?   ?   A . n 
A 1 49  GLU 49  49  ?   ?   ?   A . n 
A 1 50  MET 50  50  ?   ?   ?   A . n 
A 1 51  PRO 51  51  ?   ?   ?   A . n 
A 1 52  PHE 52  52  ?   ?   ?   A . n 
A 1 53  HIS 53  53  ?   ?   ?   A . n 
A 1 54  HIS 54  54  54  HIS HIS A . n 
A 1 55  CYS 55  55  55  CYS CYS A . n 
A 1 56  HIS 56  56  56  HIS HIS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  PRO 59  59  59  PRO PRO A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  GLY 64  64  64  GLY GLY A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  PRO 67  67  67  PRO PRO A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  ARG 69  69  69  ARG ARG A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  HIS 71  71  71  HIS HIS A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  TYR 77  77  77  TYR TYR A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  ALA 79  79  79  ALA ALA A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  CYS 83  83  83  CYS CYS A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  MET 87  87  87  MET MET A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  TYR 95  95  95  TYR TYR A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  HIS 98  98  98  HIS HIS A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 ALA 101 101 101 ALA ALA A . n 
A 1 102 ILE 102 102 102 ILE ILE A . n 
A 1 103 MET 103 103 103 MET MET A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 ALA 107 107 107 ALA ALA A . n 
A 1 108 HIS 108 108 108 HIS HIS A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 MET 116 116 116 MET MET A . n 
A 1 117 MET 117 117 117 MET MET A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 SER 119 119 119 SER SER A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 SER 122 122 122 SER SER A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 TRP 124 124 124 TRP TRP A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 ARG 132 132 132 ARG ARG A . n 
A 1 133 THR 133 133 133 THR THR A . n 
A 1 134 MET 134 134 134 MET MET A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 TRP 138 138 138 TRP TRP A . n 
A 1 139 HIS 139 139 139 HIS HIS A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 GLU 142 142 142 GLU GLU A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 SER 152 152 152 SER SER A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 TRP 154 154 154 TRP TRP A . n 
A 1 155 MET 155 155 155 MET MET A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 ILE 159 159 159 ILE ILE A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 HIS 170 170 170 HIS HIS A . n 
A 1 171 SER 171 171 171 SER SER A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 TYR 173 173 173 TYR TYR A . n 
A 1 174 HIS 174 174 174 HIS HIS A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 GLU 176 176 176 GLU GLU A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 MET 180 180 180 MET MET A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 CYS 189 189 189 CYS CYS A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 ASN 191 191 191 ASN ASN A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 HIS 199 199 199 HIS HIS A . n 
A 1 200 GLN 200 200 200 GLN GLN A . n 
A 1 201 ALA 201 201 201 ALA ALA A . n 
A 1 202 GLY 202 202 ?   ?   ?   A . n 
A 1 203 PRO 203 203 ?   ?   ?   A . n 
A 1 204 PRO 204 204 ?   ?   ?   A . n 
A 1 205 HIS 205 205 ?   ?   ?   A . n 
A 1 206 SER 206 206 ?   ?   ?   A . n 
A 1 207 HIS 207 207 ?   ?   ?   A . n 
A 1 208 GLY 208 208 ?   ?   ?   A . n 
A 1 209 SER 209 209 ?   ?   ?   A . n 
A 1 210 ARG 210 210 ?   ?   ?   A . n 
A 1 211 GLY 211 211 ?   ?   ?   A . n 
A 1 212 ALA 212 212 ?   ?   ?   A . n 
A 1 213 GLU 213 213 ?   ?   ?   A . n 
A 1 214 TYR 214 214 ?   ?   ?   A . n 
A 1 215 ALA 215 215 ?   ?   ?   A . n 
A 1 216 PRO 216 216 ?   ?   ?   A . n 
A 1 217 LEU 217 217 ?   ?   ?   A . n 
A 1 218 GLU 218 218 ?   ?   ?   A . n 
A 1 219 GLU 219 219 ?   ?   ?   A . n 
A 1 220 GLY 220 220 ?   ?   ?   A . n 
A 1 221 PRO 221 221 ?   ?   ?   A . n 
A 1 222 GLU 222 222 ?   ?   ?   A . n 
A 1 223 GLU 223 223 ?   ?   ?   A . n 
A 1 224 PRO 224 224 ?   ?   ?   A . n 
A 1 225 LEU 225 225 ?   ?   ?   A . n 
A 1 226 PRO 226 226 ?   ?   ?   A . n 
A 1 227 LEU 227 227 ?   ?   ?   A . n 
A 1 228 GLY 228 228 ?   ?   ?   A . n 
A 1 229 ASN 229 229 ?   ?   ?   A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 ARG 233 233 233 ARG ARG A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 PHE 236 236 236 PHE PHE A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 GLN 245 245 245 GLN GLN A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLY 248 248 248 GLY GLY A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 TYR 257 257 257 TYR TYR A . n 
A 1 258 PHE 258 258 258 PHE PHE A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 PRO 260 260 260 PRO PRO A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 LYS 263 263 263 LYS LYS A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 ASP 266 266 266 ASP ASP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 PHE 271 271 271 PHE PHE A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 PHE 273 273 273 PHE PHE A . n 
A 1 274 SER 274 274 274 SER SER A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 CYS 276 276 276 CYS CYS A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 GLY 279 279 279 GLY GLY A . n 
A 1 280 SER 280 280 280 SER SER A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 ARG 290 290 290 ARG ARG A . n 
A 1 291 ILE 291 291 291 ILE ILE A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 MET 293 293 293 MET MET A . n 
A 1 294 GLU 294 294 294 GLU GLU A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 PRO 297 297 297 PRO PRO A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 ASN 299 299 299 ASN ASN A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 GLY 301 301 301 GLY GLY A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 GLU 303 303 303 GLU GLU A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 VAL 305 305 305 VAL VAL A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 PRO 313 313 313 PRO PRO A . n 
A 1 314 GLY 314 314 314 GLY GLY A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 ARG 316 316 316 ARG ARG A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 HIS 319 319 319 HIS HIS A . n 
A 1 320 GLU 320 320 320 GLU GLU A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 HIS 322 322 322 HIS HIS A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 TRP 324 324 324 TRP TRP A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 HIS 331 331 331 HIS HIS A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 ALA 335 335 335 ALA ALA A . n 
A 1 336 HIS 336 336 336 HIS HIS A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 PRO 345 345 345 PRO PRO A . n 
A 1 346 GLU 346 346 346 GLU GLU A . n 
A 1 347 ALA 347 347 347 ALA ALA A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 SER 354 354 354 SER SER A . n 
A 1 355 ARG 355 355 355 ARG ARG A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 TYR 357 357 357 TYR TYR A . n 
A 1 358 SER 358 358 358 SER SER A . n 
A 1 359 ARG 359 359 359 ARG ARG A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 SER 364 364 364 SER SER A . n 
A 1 365 CYS 365 365 365 CYS CYS A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 LEU 367 367 367 LEU LEU A . n 
A 1 368 GLN 368 368 368 GLN GLN A . n 
A 1 369 VAL 369 369 369 VAL VAL A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 GLN 371 371 371 GLN GLN A . n 
A 1 372 TYR 372 372 372 TYR TYR A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 PRO 374 374 374 PRO PRO A . n 
A 1 375 GLU 375 375 375 GLU GLU A . n 
A 1 376 MET 376 376 376 MET MET A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 GLN 378 378 378 GLN GLN A . n 
A 1 379 CYS 379 379 379 CYS CYS A . n 
A 1 380 LEU 380 380 380 LEU LEU A . n 
A 1 381 ARG 381 381 381 ARG ARG A . n 
A 1 382 CYS 382 382 382 CYS CYS A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 GLU 384 384 384 GLU GLU A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 PRO 386 386 386 PRO PRO A . n 
A 1 387 GLN 387 387 387 GLN GLN A . n 
A 1 388 ALA 388 388 388 ALA ALA A . n 
A 1 389 GLY 389 389 ?   ?   ?   A . n 
A 1 390 SER 390 390 ?   ?   ?   A . n 
A 1 391 ILE 391 391 ?   ?   ?   A . n 
A 1 392 GLU 392 392 ?   ?   ?   A . n 
A 1 393 GLY 393 393 ?   ?   ?   A . n 
A 1 394 ARG 394 394 ?   ?   ?   A . n 
A 1 395 ILE 395 395 ?   ?   ?   A . n 
A 1 396 VAL 396 396 ?   ?   ?   A . n 
A 1 397 LYS 397 397 ?   ?   ?   A . n 
A 1 398 ASP 398 398 ?   ?   ?   A . n 
A 1 399 TYR 399 399 ?   ?   ?   A . n 
A 1 400 LYS 400 400 ?   ?   ?   A . n 
A 1 401 ASP 401 401 ?   ?   ?   A . n 
A 1 402 ASP 402 402 ?   ?   ?   A . n 
A 1 403 ASP 403 403 ?   ?   ?   A . n 
A 1 404 ASP 404 404 ?   ?   ?   A . n 
A 1 405 LYS 405 405 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLU 2   2   ?   ?   ?   B . n 
B 1 3   PRO 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   PRO 5   5   ?   ?   ?   B . n 
B 1 6   ALA 6   6   ?   ?   ?   B . n 
B 1 7   ALA 7   7   ?   ?   ?   B . n 
B 1 8   GLY 8   8   ?   ?   ?   B . n 
B 1 9   GLY 9   9   ?   ?   ?   B . n 
B 1 10  LEU 10  10  ?   ?   ?   B . n 
B 1 11  GLU 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  THR 13  13  ?   ?   ?   B . n 
B 1 14  ARG 14  14  ?   ?   ?   B . n 
B 1 15  LEU 15  15  ?   ?   ?   B . n 
B 1 16  VAL 16  16  ?   ?   ?   B . n 
B 1 17  SER 17  17  ?   ?   ?   B . n 
B 1 18  PRO 18  18  ?   ?   ?   B . n 
B 1 19  ARG 19  19  ?   ?   ?   B . n 
B 1 20  ASP 20  20  ?   ?   ?   B . n 
B 1 21  ARG 21  21  ?   ?   ?   B . n 
B 1 22  GLY 22  22  ?   ?   ?   B . n 
B 1 23  GLY 23  23  ?   ?   ?   B . n 
B 1 24  ALA 24  24  ?   ?   ?   B . n 
B 1 25  GLY 25  25  ?   ?   ?   B . n 
B 1 26  GLY 26  26  ?   ?   ?   B . n 
B 1 27  SER 27  27  ?   ?   ?   B . n 
B 1 28  LEU 28  28  ?   ?   ?   B . n 
B 1 29  ARG 29  29  ?   ?   ?   B . n 
B 1 30  LEU 30  30  ?   ?   ?   B . n 
B 1 31  LYS 31  31  ?   ?   ?   B . n 
B 1 32  SER 32  32  ?   ?   ?   B . n 
B 1 33  LEU 33  33  ?   ?   ?   B . n 
B 1 34  PHE 34  34  ?   ?   ?   B . n 
B 1 35  THR 35  35  ?   ?   ?   B . n 
B 1 36  GLU 36  36  ?   ?   ?   B . n 
B 1 37  PRO 37  37  ?   ?   ?   B . n 
B 1 38  SER 38  38  ?   ?   ?   B . n 
B 1 39  GLU 39  39  ?   ?   ?   B . n 
B 1 40  PRO 40  40  ?   ?   ?   B . n 
B 1 41  LEU 41  41  ?   ?   ?   B . n 
B 1 42  PRO 42  42  ?   ?   ?   B . n 
B 1 43  GLU 43  43  ?   ?   ?   B . n 
B 1 44  GLU 44  44  ?   ?   ?   B . n 
B 1 45  SER 45  45  ?   ?   ?   B . n 
B 1 46  LYS 46  46  ?   ?   ?   B . n 
B 1 47  PRO 47  47  ?   ?   ?   B . n 
B 1 48  VAL 48  48  ?   ?   ?   B . n 
B 1 49  GLU 49  49  ?   ?   ?   B . n 
B 1 50  MET 50  50  ?   ?   ?   B . n 
B 1 51  PRO 51  51  ?   ?   ?   B . n 
B 1 52  PHE 52  52  ?   ?   ?   B . n 
B 1 53  HIS 53  53  ?   ?   ?   B . n 
B 1 54  HIS 54  54  54  HIS HIS B . n 
B 1 55  CYS 55  55  55  CYS CYS B . n 
B 1 56  HIS 56  56  56  HIS HIS B . n 
B 1 57  ARG 57  57  57  ARG ARG B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  PRO 59  59  59  PRO PRO B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  PRO 61  61  61  PRO PRO B . n 
B 1 62  PRO 62  62  62  PRO PRO B . n 
B 1 63  PRO 63  63  63  PRO PRO B . n 
B 1 64  GLY 64  64  64  GLY GLY B . n 
B 1 65  LEU 65  65  65  LEU LEU B . n 
B 1 66  THR 66  66  66  THR THR B . n 
B 1 67  PRO 67  67  67  PRO PRO B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  ARG 69  69  69  ARG ARG B . n 
B 1 70  LEU 70  70  70  LEU LEU B . n 
B 1 71  HIS 71  71  71  HIS HIS B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  ARG 74  74  74  ARG ARG B . n 
B 1 75  GLN 75  75  75  GLN GLN B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  TYR 77  77  77  TYR TYR B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  ALA 79  79  79  ALA ALA B . n 
B 1 80  CYS 80  80  80  CYS CYS B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  VAL 82  82  82  VAL VAL B . n 
B 1 83  CYS 83  83  83  CYS CYS B . n 
B 1 84  PHE 84  84  84  PHE PHE B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  PHE 86  86  86  PHE PHE B . n 
B 1 87  MET 87  87  87  MET MET B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  TYR 95  95  95  TYR TYR B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  HIS 98  98  98  HIS HIS B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 ALA 101 101 101 ALA ALA B . n 
B 1 102 ILE 102 102 102 ILE ILE B . n 
B 1 103 MET 103 103 103 MET MET B . n 
B 1 104 THR 104 104 104 THR THR B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 ALA 106 106 106 ALA ALA B . n 
B 1 107 ALA 107 107 107 ALA ALA B . n 
B 1 108 HIS 108 108 108 HIS HIS B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 ALA 111 111 111 ALA ALA B . n 
B 1 112 ASP 112 112 112 ASP ASP B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 MET 116 116 116 MET MET B . n 
B 1 117 MET 117 117 117 MET MET B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 SER 119 119 119 SER SER B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 SER 122 122 122 SER SER B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 TRP 124 124 124 TRP TRP B . n 
B 1 125 LEU 125 125 125 LEU LEU B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 THR 127 127 127 THR THR B . n 
B 1 128 ARG 128 128 128 ARG ARG B . n 
B 1 129 PRO 129 129 129 PRO PRO B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 ARG 132 132 132 ARG ARG B . n 
B 1 133 THR 133 133 133 THR THR B . n 
B 1 134 MET 134 134 134 MET MET B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 PHE 136 136 136 PHE PHE B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 TRP 138 138 138 TRP TRP B . n 
B 1 139 HIS 139 139 139 HIS HIS B . n 
B 1 140 ARG 140 140 140 ARG ARG B . n 
B 1 141 SER 141 141 141 SER SER B . n 
B 1 142 GLU 142 142 142 GLU GLU B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 SER 149 149 149 SER SER B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 SER 152 152 152 SER SER B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 TRP 154 154 154 TRP TRP B . n 
B 1 155 MET 155 155 155 MET MET B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 ILE 159 159 159 ILE ILE B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 TYR 162 162 162 TYR TYR B . n 
B 1 163 LEU 163 163 163 LEU LEU B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 VAL 166 166 166 VAL VAL B . n 
B 1 167 ARG 167 167 167 ARG ARG B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 HIS 170 170 170 HIS HIS B . n 
B 1 171 SER 171 171 171 SER SER B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 TYR 173 173 173 TYR TYR B . n 
B 1 174 HIS 174 174 174 HIS HIS B . n 
B 1 175 ILE 175 175 175 ILE ILE B . n 
B 1 176 GLU 176 176 176 GLU GLU B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 MET 180 180 180 MET MET B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 THR 183 183 183 THR THR B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 VAL 188 188 188 VAL VAL B . n 
B 1 189 CYS 189 189 189 CYS CYS B . n 
B 1 190 ALA 190 190 190 ALA ALA B . n 
B 1 191 ASN 191 191 191 ASN ASN B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 ALA 195 195 195 ALA ALA B . n 
B 1 196 PHE 196 196 196 PHE PHE B . n 
B 1 197 VAL 197 197 197 VAL VAL B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 HIS 199 199 199 HIS HIS B . n 
B 1 200 GLN 200 200 200 GLN GLN B . n 
B 1 201 ALA 201 201 201 ALA ALA B . n 
B 1 202 GLY 202 202 ?   ?   ?   B . n 
B 1 203 PRO 203 203 ?   ?   ?   B . n 
B 1 204 PRO 204 204 ?   ?   ?   B . n 
B 1 205 HIS 205 205 ?   ?   ?   B . n 
B 1 206 SER 206 206 ?   ?   ?   B . n 
B 1 207 HIS 207 207 ?   ?   ?   B . n 
B 1 208 GLY 208 208 ?   ?   ?   B . n 
B 1 209 SER 209 209 ?   ?   ?   B . n 
B 1 210 ARG 210 210 ?   ?   ?   B . n 
B 1 211 GLY 211 211 ?   ?   ?   B . n 
B 1 212 ALA 212 212 ?   ?   ?   B . n 
B 1 213 GLU 213 213 ?   ?   ?   B . n 
B 1 214 TYR 214 214 ?   ?   ?   B . n 
B 1 215 ALA 215 215 ?   ?   ?   B . n 
B 1 216 PRO 216 216 ?   ?   ?   B . n 
B 1 217 LEU 217 217 ?   ?   ?   B . n 
B 1 218 GLU 218 218 ?   ?   ?   B . n 
B 1 219 GLU 219 219 ?   ?   ?   B . n 
B 1 220 GLY 220 220 ?   ?   ?   B . n 
B 1 221 PRO 221 221 ?   ?   ?   B . n 
B 1 222 GLU 222 222 ?   ?   ?   B . n 
B 1 223 GLU 223 223 ?   ?   ?   B . n 
B 1 224 PRO 224 224 ?   ?   ?   B . n 
B 1 225 LEU 225 225 ?   ?   ?   B . n 
B 1 226 PRO 226 226 ?   ?   ?   B . n 
B 1 227 LEU 227 227 ?   ?   ?   B . n 
B 1 228 GLY 228 228 ?   ?   ?   B . n 
B 1 229 ASN 229 229 ?   ?   ?   B . n 
B 1 230 THR 230 230 230 THR THR B . n 
B 1 231 SER 231 231 231 SER SER B . n 
B 1 232 VAL 232 232 232 VAL VAL B . n 
B 1 233 ARG 233 233 233 ARG ARG B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 ALA 235 235 235 ALA ALA B . n 
B 1 236 PHE 236 236 236 PHE PHE B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 LEU 244 244 244 LEU LEU B . n 
B 1 245 GLN 245 245 245 GLN GLN B . n 
B 1 246 SER 246 246 246 SER SER B . n 
B 1 247 PHE 247 247 247 PHE PHE B . n 
B 1 248 GLY 248 248 248 GLY GLY B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ILE 254 254 254 ILE ILE B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 TYR 257 257 257 TYR TYR B . n 
B 1 258 PHE 258 258 258 PHE PHE B . n 
B 1 259 LYS 259 259 259 LYS LYS B . n 
B 1 260 PRO 260 260 260 PRO PRO B . n 
B 1 261 GLN 261 261 261 GLN GLN B . n 
B 1 262 TYR 262 262 262 TYR TYR B . n 
B 1 263 LYS 263 263 263 LYS LYS B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 ASP 266 266 266 ASP ASP B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 ILE 268 268 268 ILE ILE B . n 
B 1 269 SER 269 269 269 SER SER B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 PHE 271 271 271 PHE PHE B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 PHE 273 273 273 PHE PHE B . n 
B 1 274 SER 274 274 274 SER SER B . n 
B 1 275 ILE 275 275 275 ILE ILE B . n 
B 1 276 CYS 276 276 276 CYS CYS B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 GLY 279 279 279 GLY GLY B . n 
B 1 280 SER 280 280 280 SER SER B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 PRO 283 283 283 PRO PRO B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 ASP 287 287 287 ASP ASP B . n 
B 1 288 VAL 288 288 288 VAL VAL B . n 
B 1 289 LEU 289 289 289 LEU LEU B . n 
B 1 290 ARG 290 290 290 ARG ARG B . n 
B 1 291 ILE 291 291 291 ILE ILE B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 MET 293 293 293 MET MET B . n 
B 1 294 GLU 294 294 294 GLU GLU B . n 
B 1 295 GLY 295 295 295 GLY GLY B . n 
B 1 296 THR 296 296 296 THR THR B . n 
B 1 297 PRO 297 297 297 PRO PRO B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 ASN 299 299 299 ASN ASN B . n 
B 1 300 VAL 300 300 300 VAL VAL B . n 
B 1 301 GLY 301 301 301 GLY GLY B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 GLU 303 303 303 GLU GLU B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 VAL 305 305 305 VAL VAL B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 PRO 313 313 313 PRO PRO B . n 
B 1 314 GLY 314 314 314 GLY GLY B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 ARG 316 316 316 ARG ARG B . n 
B 1 317 ALA 317 317 317 ALA ALA B . n 
B 1 318 THR 318 318 318 THR THR B . n 
B 1 319 HIS 319 319 319 HIS HIS B . n 
B 1 320 GLU 320 320 320 GLU GLU B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 HIS 322 322 322 HIS HIS B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 TRP 324 324 324 TRP TRP B . n 
B 1 325 ALA 325 325 325 ALA ALA B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 THR 327 327 327 THR THR B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 THR 329 329 329 THR THR B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 HIS 331 331 331 HIS HIS B . n 
B 1 332 VAL 332 332 332 VAL VAL B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 SER 334 334 334 SER SER B . n 
B 1 335 ALA 335 335 335 ALA ALA B . n 
B 1 336 HIS 336 336 336 HIS HIS B . n 
B 1 337 LEU 337 337 337 LEU LEU B . n 
B 1 338 ALA 338 338 338 ALA ALA B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 SER 341 341 341 SER SER B . n 
B 1 342 THR 342 342 342 THR THR B . n 
B 1 343 ALA 343 343 343 ALA ALA B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 PRO 345 345 345 PRO PRO B . n 
B 1 346 GLU 346 346 346 GLU GLU B . n 
B 1 347 ALA 347 347 347 ALA ALA B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 LEU 349 349 349 LEU LEU B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 ALA 352 352 352 ALA ALA B . n 
B 1 353 SER 353 353 353 SER SER B . n 
B 1 354 SER 354 354 354 SER SER B . n 
B 1 355 ARG 355 355 355 ARG ARG B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 TYR 357 357 357 TYR TYR B . n 
B 1 358 SER 358 358 358 SER SER B . n 
B 1 359 ARG 359 359 359 ARG ARG B . n 
B 1 360 PHE 360 360 360 PHE PHE B . n 
B 1 361 GLY 361 361 361 GLY GLY B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 SER 364 364 364 SER SER B . n 
B 1 365 CYS 365 365 365 CYS CYS B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 LEU 367 367 367 LEU LEU B . n 
B 1 368 GLN 368 368 368 GLN GLN B . n 
B 1 369 VAL 369 369 369 VAL VAL B . n 
B 1 370 GLU 370 370 370 GLU GLU B . n 
B 1 371 GLN 371 371 371 GLN GLN B . n 
B 1 372 TYR 372 372 372 TYR TYR B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 PRO 374 374 374 PRO PRO B . n 
B 1 375 GLU 375 375 375 GLU GLU B . n 
B 1 376 MET 376 376 376 MET MET B . n 
B 1 377 ALA 377 377 377 ALA ALA B . n 
B 1 378 GLN 378 378 378 GLN GLN B . n 
B 1 379 CYS 379 379 379 CYS CYS B . n 
B 1 380 LEU 380 380 380 LEU LEU B . n 
B 1 381 ARG 381 381 381 ARG ARG B . n 
B 1 382 CYS 382 382 382 CYS CYS B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 GLU 384 384 384 GLU GLU B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 PRO 386 386 386 PRO PRO B . n 
B 1 387 GLN 387 387 387 GLN GLN B . n 
B 1 388 ALA 388 388 388 ALA ALA B . n 
B 1 389 GLY 389 389 ?   ?   ?   B . n 
B 1 390 SER 390 390 ?   ?   ?   B . n 
B 1 391 ILE 391 391 ?   ?   ?   B . n 
B 1 392 GLU 392 392 ?   ?   ?   B . n 
B 1 393 GLY 393 393 ?   ?   ?   B . n 
B 1 394 ARG 394 394 ?   ?   ?   B . n 
B 1 395 ILE 395 395 ?   ?   ?   B . n 
B 1 396 VAL 396 396 ?   ?   ?   B . n 
B 1 397 LYS 397 397 ?   ?   ?   B . n 
B 1 398 ASP 398 398 ?   ?   ?   B . n 
B 1 399 TYR 399 399 ?   ?   ?   B . n 
B 1 400 LYS 400 400 ?   ?   ?   B . n 
B 1 401 ASP 401 401 ?   ?   ?   B . n 
B 1 402 ASP 402 402 ?   ?   ?   B . n 
B 1 403 ASP 403 403 ?   ?   ?   B . n 
B 1 404 ASP 404 404 ?   ?   ?   B . n 
B 1 405 LYS 405 405 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 ZN  1 801 801 ZN  ZN  A . 
D 2 ZN  1 802 802 ZN  ZN  A . 
E 3 AV0 1 803 811 AV0 AV0 A . 
F 2 ZN  1 804 803 ZN  ZN  A . 
G 2 ZN  1 501 803 ZN  ZN  B . 
H 2 ZN  1 502 801 ZN  ZN  B . 
I 2 ZN  1 503 802 ZN  ZN  B . 
J 3 AV0 1 504 811 AV0 AV0 B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JJ1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JJ1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JJ1 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9JJ1 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 4960 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.492  ? 6764 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.707 ? 702  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.035  ? 814  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 826  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JJ1 
_struct.title                        'Cryo-EM structure of human ZnT3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JJ1 
_struct_keywords.text            'zinc transporter, membrane protein, ZnT, antiporter' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ZNT3_HUMAN 
_struct_ref.pdbx_db_accession          Q99726 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JJ1 A 1 ? 388 ? Q99726 1 ? 388 ? 1 388 
2 1 9JJ1 B 1 ? 388 ? Q99726 1 ? 388 ? 1 388 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JJ1 GLY A 389 ? UNP Q99726 ? ? 'expression tag' 389 1  
1 9JJ1 SER A 390 ? UNP Q99726 ? ? 'expression tag' 390 2  
1 9JJ1 ILE A 391 ? UNP Q99726 ? ? 'expression tag' 391 3  
1 9JJ1 GLU A 392 ? UNP Q99726 ? ? 'expression tag' 392 4  
1 9JJ1 GLY A 393 ? UNP Q99726 ? ? 'expression tag' 393 5  
1 9JJ1 ARG A 394 ? UNP Q99726 ? ? 'expression tag' 394 6  
1 9JJ1 ILE A 395 ? UNP Q99726 ? ? 'expression tag' 395 7  
1 9JJ1 VAL A 396 ? UNP Q99726 ? ? 'expression tag' 396 8  
1 9JJ1 LYS A 397 ? UNP Q99726 ? ? 'expression tag' 397 9  
1 9JJ1 ASP A 398 ? UNP Q99726 ? ? 'expression tag' 398 10 
1 9JJ1 TYR A 399 ? UNP Q99726 ? ? 'expression tag' 399 11 
1 9JJ1 LYS A 400 ? UNP Q99726 ? ? 'expression tag' 400 12 
1 9JJ1 ASP A 401 ? UNP Q99726 ? ? 'expression tag' 401 13 
1 9JJ1 ASP A 402 ? UNP Q99726 ? ? 'expression tag' 402 14 
1 9JJ1 ASP A 403 ? UNP Q99726 ? ? 'expression tag' 403 15 
1 9JJ1 ASP A 404 ? UNP Q99726 ? ? 'expression tag' 404 16 
1 9JJ1 LYS A 405 ? UNP Q99726 ? ? 'expression tag' 405 17 
2 9JJ1 GLY B 389 ? UNP Q99726 ? ? 'expression tag' 389 18 
2 9JJ1 SER B 390 ? UNP Q99726 ? ? 'expression tag' 390 19 
2 9JJ1 ILE B 391 ? UNP Q99726 ? ? 'expression tag' 391 20 
2 9JJ1 GLU B 392 ? UNP Q99726 ? ? 'expression tag' 392 21 
2 9JJ1 GLY B 393 ? UNP Q99726 ? ? 'expression tag' 393 22 
2 9JJ1 ARG B 394 ? UNP Q99726 ? ? 'expression tag' 394 23 
2 9JJ1 ILE B 395 ? UNP Q99726 ? ? 'expression tag' 395 24 
2 9JJ1 VAL B 396 ? UNP Q99726 ? ? 'expression tag' 396 25 
2 9JJ1 LYS B 397 ? UNP Q99726 ? ? 'expression tag' 397 26 
2 9JJ1 ASP B 398 ? UNP Q99726 ? ? 'expression tag' 398 27 
2 9JJ1 TYR B 399 ? UNP Q99726 ? ? 'expression tag' 399 28 
2 9JJ1 LYS B 400 ? UNP Q99726 ? ? 'expression tag' 400 29 
2 9JJ1 ASP B 401 ? UNP Q99726 ? ? 'expression tag' 401 30 
2 9JJ1 ASP B 402 ? UNP Q99726 ? ? 'expression tag' 402 31 
2 9JJ1 ASP B 403 ? UNP Q99726 ? ? 'expression tag' 403 32 
2 9JJ1 ASP B 404 ? UNP Q99726 ? ? 'expression tag' 404 33 
2 9JJ1 LYS B 405 ? UNP Q99726 ? ? 'expression tag' 405 34 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 66  ? HIS A 98  ? THR A 66  HIS A 98  1 ? 33 
HELX_P HELX_P2  AA2 LEU A 100 ? SER A 126 ? LEU A 100 SER A 126 1 ? 27 
HELX_P HELX_P3  AA3 HIS A 139 ? LEU A 169 ? HIS A 139 LEU A 169 1 ? 31 
HELX_P HELX_P4  AA4 GLU A 176 ? ALA A 201 ? GLU A 176 ALA A 201 1 ? 26 
HELX_P HELX_P5  AA5 SER A 231 ? LYS A 259 ? SER A 231 LYS A 259 1 ? 29 
HELX_P HELX_P6  AA6 ALA A 264 ? MET A 293 ? ALA A 264 MET A 293 1 ? 30 
HELX_P HELX_P7  AA7 GLY A 301 ? SER A 311 ? GLY A 301 SER A 311 1 ? 11 
HELX_P HELX_P8  AA8 ASP A 344 ? GLY A 361 ? ASP A 344 GLY A 361 1 ? 18 
HELX_P HELX_P9  AA9 GLU A 375 ? GLN A 383 ? GLU A 375 GLN A 383 5 ? 9  
HELX_P HELX_P10 AB1 THR B 66  ? HIS B 98  ? THR B 66  HIS B 98  1 ? 33 
HELX_P HELX_P11 AB2 LEU B 100 ? SER B 126 ? LEU B 100 SER B 126 1 ? 27 
HELX_P HELX_P12 AB3 HIS B 139 ? LEU B 169 ? HIS B 139 LEU B 169 1 ? 31 
HELX_P HELX_P13 AB4 GLU B 176 ? ALA B 201 ? GLU B 176 ALA B 201 1 ? 26 
HELX_P HELX_P14 AB5 SER B 231 ? LYS B 259 ? SER B 231 LYS B 259 1 ? 29 
HELX_P HELX_P15 AB6 ALA B 264 ? MET B 293 ? ALA B 264 MET B 293 1 ? 30 
HELX_P HELX_P16 AB7 GLY B 301 ? SER B 311 ? GLY B 301 SER B 311 1 ? 11 
HELX_P HELX_P17 AB8 ASP B 344 ? GLY B 361 ? ASP B 344 GLY B 361 1 ? 18 
HELX_P HELX_P18 AB9 GLU B 375 ? CYS B 379 ? GLU B 375 CYS B 379 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS 54  NE2 ? ? ? 1_555 D ZN  .   ZN ? ? A HIS 54  A ZN  802 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
metalc2  metalc ? ? A CYS 55  SG  ? ? ? 1_555 G ZN  .   ZN ? ? A CYS 55  B ZN  501 1_555 ? ? ? ? ? ? ? 2.298 ? ? 
metalc3  metalc ? ? A HIS 56  NE2 ? ? ? 1_555 D ZN  .   ZN ? ? A HIS 56  A ZN  802 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
metalc4  metalc ? ? A HIS 108 NE2 ? ? ? 1_555 C ZN  .   ZN ? ? A HIS 108 A ZN  801 1_555 ? ? ? ? ? ? ? 2.290 ? ? 
metalc5  metalc ? ? A ASP 112 OD2 ? ? ? 1_555 C ZN  .   ZN ? ? A ASP 112 A ZN  801 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
metalc6  metalc ? ? A HIS 238 NE2 ? ? ? 1_555 C ZN  .   ZN ? ? A HIS 238 A ZN  801 1_555 ? ? ? ? ? ? ? 2.291 ? ? 
metalc7  metalc ? ? A ASP 242 OD1 ? ? ? 1_555 C ZN  .   ZN ? ? A ASP 242 A ZN  801 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
metalc8  metalc ? ? A ASP 242 OD2 ? ? ? 1_555 C ZN  .   ZN ? ? A ASP 242 A ZN  801 1_555 ? ? ? ? ? ? ? 1.966 ? ? 
metalc9  metalc ? ? A HIS 319 NE2 ? ? ? 1_555 F ZN  .   ZN ? ? A HIS 319 A ZN  804 1_555 ? ? ? ? ? ? ? 2.292 ? ? 
metalc10 metalc ? ? A HIS 336 ND1 ? ? ? 1_555 F ZN  .   ZN ? ? A HIS 336 A ZN  804 1_555 ? ? ? ? ? ? ? 2.294 ? ? 
metalc11 metalc ? ? A GLU 370 OE1 ? ? ? 1_555 F ZN  .   ZN ? ? A GLU 370 A ZN  804 1_555 ? ? ? ? ? ? ? 1.985 ? ? 
metalc12 metalc ? ? A GLU 370 OE2 ? ? ? 1_555 F ZN  .   ZN ? ? A GLU 370 A ZN  804 1_555 ? ? ? ? ? ? ? 1.970 ? ? 
metalc13 metalc ? ? A CYS 379 SG  ? ? ? 1_555 I ZN  .   ZN ? ? A CYS 379 B ZN  503 1_555 ? ? ? ? ? ? ? 2.304 ? ? 
metalc14 metalc ? ? A CYS 382 SG  ? ? ? 1_555 I ZN  .   ZN ? ? A CYS 382 B ZN  503 1_555 ? ? ? ? ? ? ? 2.306 ? ? 
metalc15 metalc ? ? D ZN  .   ZN  ? ? ? 1_555 B CYS 379 SG ? ? A ZN  802 B CYS 379 1_555 ? ? ? ? ? ? ? 2.304 ? ? 
metalc16 metalc ? ? D ZN  .   ZN  ? ? ? 1_555 B CYS 382 SG ? ? A ZN  802 B CYS 382 1_555 ? ? ? ? ? ? ? 2.306 ? ? 
metalc17 metalc ? ? F ZN  .   ZN  ? ? ? 1_555 B CYS 55  SG ? ? A ZN  804 B CYS 55  1_555 ? ? ? ? ? ? ? 2.299 ? ? 
metalc18 metalc ? ? B HIS 54  NE2 ? ? ? 1_555 I ZN  .   ZN ? ? B HIS 54  B ZN  503 1_555 ? ? ? ? ? ? ? 2.052 ? ? 
metalc19 metalc ? ? B HIS 56  NE2 ? ? ? 1_555 I ZN  .   ZN ? ? B HIS 56  B ZN  503 1_555 ? ? ? ? ? ? ? 2.053 ? ? 
metalc20 metalc ? ? B HIS 108 NE2 ? ? ? 1_555 H ZN  .   ZN ? ? B HIS 108 B ZN  502 1_555 ? ? ? ? ? ? ? 2.290 ? ? 
metalc21 metalc ? ? B ASP 112 OD2 ? ? ? 1_555 H ZN  .   ZN ? ? B ASP 112 B ZN  502 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
metalc22 metalc ? ? B HIS 238 NE2 ? ? ? 1_555 H ZN  .   ZN ? ? B HIS 238 B ZN  502 1_555 ? ? ? ? ? ? ? 2.292 ? ? 
metalc23 metalc ? ? B ASP 242 OD1 ? ? ? 1_555 H ZN  .   ZN ? ? B ASP 242 B ZN  502 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
metalc24 metalc ? ? B ASP 242 OD2 ? ? ? 1_555 H ZN  .   ZN ? ? B ASP 242 B ZN  502 1_555 ? ? ? ? ? ? ? 1.965 ? ? 
metalc25 metalc ? ? B HIS 319 ND1 ? ? ? 1_555 G ZN  .   ZN ? ? B HIS 319 B ZN  501 1_555 ? ? ? ? ? ? ? 2.692 ? ? 
metalc26 metalc ? ? B HIS 319 NE2 ? ? ? 1_555 G ZN  .   ZN ? ? B HIS 319 B ZN  501 1_555 ? ? ? ? ? ? ? 2.299 ? ? 
metalc27 metalc ? ? B HIS 336 ND1 ? ? ? 1_555 G ZN  .   ZN ? ? B HIS 336 B ZN  501 1_555 ? ? ? ? ? ? ? 2.304 ? ? 
metalc28 metalc ? ? B GLU 370 OE1 ? ? ? 1_555 G ZN  .   ZN ? ? B GLU 370 B ZN  501 1_555 ? ? ? ? ? ? ? 2.001 ? ? 
metalc29 metalc ? ? B GLU 370 OE2 ? ? ? 1_555 G ZN  .   ZN ? ? B GLU 370 B ZN  501 1_555 ? ? ? ? ? ? ? 1.982 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 54  ? A HIS 54  ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 NE2 ? A HIS 56  ? A HIS 56  ? 1_555 103.5 ? 
2  NE2 ? A HIS 54  ? A HIS 54  ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? B CYS 379 ? B CYS 379 ? 1_555 157.2 ? 
3  NE2 ? A HIS 56  ? A HIS 56  ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? B CYS 379 ? B CYS 379 ? 1_555 99.1  ? 
4  NE2 ? A HIS 54  ? A HIS 54  ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? B CYS 382 ? B CYS 382 ? 1_555 77.2  ? 
5  NE2 ? A HIS 56  ? A HIS 56  ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? B CYS 382 ? B CYS 382 ? 1_555 62.2  ? 
6  SG  ? B CYS 379 ? B CYS 379 ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? B CYS 382 ? B CYS 382 ? 1_555 116.6 ? 
7  SG  ? A CYS 55  ? A CYS 55  ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 ND1 ? B HIS 319 ? B HIS 319 ? 1_555 128.8 ? 
8  SG  ? A CYS 55  ? A CYS 55  ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 NE2 ? B HIS 319 ? B HIS 319 ? 1_555 139.5 ? 
9  ND1 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 NE2 ? B HIS 319 ? B HIS 319 ? 1_555 50.1  ? 
10 SG  ? A CYS 55  ? A CYS 55  ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 ND1 ? B HIS 336 ? B HIS 336 ? 1_555 82.0  ? 
11 ND1 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 ND1 ? B HIS 336 ? B HIS 336 ? 1_555 98.6  ? 
12 NE2 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 ND1 ? B HIS 336 ? B HIS 336 ? 1_555 136.8 ? 
13 SG  ? A CYS 55  ? A CYS 55  ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE1 ? B GLU 370 ? B GLU 370 ? 1_555 94.1  ? 
14 ND1 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE1 ? B GLU 370 ? B GLU 370 ? 1_555 120.6 ? 
15 NE2 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE1 ? B GLU 370 ? B GLU 370 ? 1_555 70.5  ? 
16 ND1 ? B HIS 336 ? B HIS 336 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE1 ? B GLU 370 ? B GLU 370 ? 1_555 130.1 ? 
17 SG  ? A CYS 55  ? A CYS 55  ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE2 ? B GLU 370 ? B GLU 370 ? 1_555 45.9  ? 
18 ND1 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE2 ? B GLU 370 ? B GLU 370 ? 1_555 172.7 ? 
19 NE2 ? B HIS 319 ? B HIS 319 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE2 ? B GLU 370 ? B GLU 370 ? 1_555 137.1 ? 
20 ND1 ? B HIS 336 ? B HIS 336 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE2 ? B GLU 370 ? B GLU 370 ? 1_555 76.3  ? 
21 OE1 ? B GLU 370 ? B GLU 370 ? 1_555 ZN ? G ZN . ? B ZN 501 ? 1_555 OE2 ? B GLU 370 ? B GLU 370 ? 1_555 66.5  ? 
22 NE2 ? A HIS 108 ? A HIS 108 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD2 ? A ASP 112 ? A ASP 112 ? 1_555 106.4 ? 
23 NE2 ? A HIS 108 ? A HIS 108 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 NE2 ? A HIS 238 ? A HIS 238 ? 1_555 103.9 ? 
24 OD2 ? A ASP 112 ? A ASP 112 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 NE2 ? A HIS 238 ? A HIS 238 ? 1_555 69.7  ? 
25 NE2 ? A HIS 108 ? A HIS 108 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD1 ? A ASP 242 ? A ASP 242 ? 1_555 66.7  ? 
26 OD2 ? A ASP 112 ? A ASP 112 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD1 ? A ASP 242 ? A ASP 242 ? 1_555 172.6 ? 
27 NE2 ? A HIS 238 ? A HIS 238 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD1 ? A ASP 242 ? A ASP 242 ? 1_555 108.5 ? 
28 NE2 ? A HIS 108 ? A HIS 108 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD2 ? A ASP 242 ? A ASP 242 ? 1_555 115.7 ? 
29 OD2 ? A ASP 112 ? A ASP 112 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD2 ? A ASP 242 ? A ASP 242 ? 1_555 120.7 ? 
30 NE2 ? A HIS 238 ? A HIS 238 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD2 ? A ASP 242 ? A ASP 242 ? 1_555 131.0 ? 
31 OD1 ? A ASP 242 ? A ASP 242 ? 1_555 ZN ? C ZN . ? A ZN 801 ? 1_555 OD2 ? A ASP 242 ? A ASP 242 ? 1_555 66.2  ? 
32 NE2 ? A HIS 319 ? A HIS 319 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 ND1 ? A HIS 336 ? A HIS 336 ? 1_555 112.6 ? 
33 NE2 ? A HIS 319 ? A HIS 319 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OE1 ? A GLU 370 ? A GLU 370 ? 1_555 80.4  ? 
34 ND1 ? A HIS 336 ? A HIS 336 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OE1 ? A GLU 370 ? A GLU 370 ? 1_555 162.1 ? 
35 NE2 ? A HIS 319 ? A HIS 319 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OE2 ? A GLU 370 ? A GLU 370 ? 1_555 125.0 ? 
36 ND1 ? A HIS 336 ? A HIS 336 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OE2 ? A GLU 370 ? A GLU 370 ? 1_555 94.9  ? 
37 OE1 ? A GLU 370 ? A GLU 370 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OE2 ? A GLU 370 ? A GLU 370 ? 1_555 67.3  ? 
38 NE2 ? A HIS 319 ? A HIS 319 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? B CYS 55  ? B CYS 55  ? 1_555 72.0  ? 
39 ND1 ? A HIS 336 ? A HIS 336 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? B CYS 55  ? B CYS 55  ? 1_555 85.2  ? 
40 OE1 ? A GLU 370 ? A GLU 370 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? B CYS 55  ? B CYS 55  ? 1_555 87.5  ? 
41 OE2 ? A GLU 370 ? A GLU 370 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? B CYS 55  ? B CYS 55  ? 1_555 63.6  ? 
42 SG  ? A CYS 379 ? A CYS 379 ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 SG  ? A CYS 382 ? A CYS 382 ? 1_555 116.4 ? 
43 SG  ? A CYS 379 ? A CYS 379 ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 NE2 ? B HIS 54  ? B HIS 54  ? 1_555 144.6 ? 
44 SG  ? A CYS 382 ? A CYS 382 ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 NE2 ? B HIS 54  ? B HIS 54  ? 1_555 67.2  ? 
45 SG  ? A CYS 379 ? A CYS 379 ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 NE2 ? B HIS 56  ? B HIS 56  ? 1_555 103.4 ? 
46 SG  ? A CYS 382 ? A CYS 382 ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 NE2 ? B HIS 56  ? B HIS 56  ? 1_555 68.6  ? 
47 NE2 ? B HIS 54  ? B HIS 54  ? 1_555 ZN ? I ZN . ? B ZN 503 ? 1_555 NE2 ? B HIS 56  ? B HIS 56  ? 1_555 109.9 ? 
48 NE2 ? B HIS 108 ? B HIS 108 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD2 ? B ASP 112 ? B ASP 112 ? 1_555 106.5 ? 
49 NE2 ? B HIS 108 ? B HIS 108 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 NE2 ? B HIS 238 ? B HIS 238 ? 1_555 104.3 ? 
50 OD2 ? B ASP 112 ? B ASP 112 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 NE2 ? B HIS 238 ? B HIS 238 ? 1_555 69.6  ? 
51 NE2 ? B HIS 108 ? B HIS 108 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD1 ? B ASP 242 ? B ASP 242 ? 1_555 66.7  ? 
52 OD2 ? B ASP 112 ? B ASP 112 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD1 ? B ASP 242 ? B ASP 242 ? 1_555 172.6 ? 
53 NE2 ? B HIS 238 ? B HIS 238 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD1 ? B ASP 242 ? B ASP 242 ? 1_555 108.6 ? 
54 NE2 ? B HIS 108 ? B HIS 108 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD2 ? B ASP 242 ? B ASP 242 ? 1_555 115.4 ? 
55 OD2 ? B ASP 112 ? B ASP 112 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD2 ? B ASP 242 ? B ASP 242 ? 1_555 120.7 ? 
56 NE2 ? B HIS 238 ? B HIS 238 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD2 ? B ASP 242 ? B ASP 242 ? 1_555 131.0 ? 
57 OD1 ? B ASP 242 ? B ASP 242 ? 1_555 ZN ? H ZN . ? B ZN 502 ? 1_555 OD2 ? B ASP 242 ? B ASP 242 ? 1_555 66.2  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 315 ? ALA A 325 ? VAL A 315 ALA A 325 
AA1 2 HIS A 331 ? ILE A 339 ? HIS A 331 ILE A 339 
AA1 3 SER A 364 ? GLN A 371 ? SER A 364 GLN A 371 
AA2 1 VAL B 315 ? ALA B 325 ? VAL B 315 ALA B 325 
AA2 2 HIS B 331 ? ILE B 339 ? HIS B 331 ILE B 339 
AA2 3 SER B 364 ? GLN B 371 ? SER B 364 GLN B 371 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TRP A 324 ? N TRP A 324 O VAL A 332 ? O VAL A 332 
AA1 2 3 N LEU A 337 ? N LEU A 337 O GLU A 370 ? O GLU A 370 
AA2 1 2 N TRP B 324 ? N TRP B 324 O VAL B 332 ? O VAL B 332 
AA2 2 3 N LEU B 337 ? N LEU B 337 O GLU B 370 ? O GLU B 370 
# 
_pdbx_entry_details.entry_id                   9JJ1 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 CE1 B HIS 319 ? ? ZN  B ZN  501 ? ? 1.59 
2 1 SG  A CYS 55  ? ? OE2 B GLU 370 ? ? 1.69 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 HIS A 56  ? ? 78.63  -2.25 
2 1 SER A 126 ? ? -80.43 45.27 
3 1 TYR A 262 ? ? -93.35 52.75 
4 1 THR A 342 ? ? -91.69 59.60 
5 1 HIS B 56  ? ? 59.74  4.21  
6 1 SER B 126 ? ? -80.38 45.29 
7 1 TYR B 262 ? ? -93.41 52.71 
8 1 THR B 342 ? ? -91.56 59.76 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JJ1 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JJ1 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.72 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               234000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 ZnT3 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JJ1 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9JJ1 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JJ1 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLU 2   ? A GLU 2   
3   1 Y 1 A PRO 3   ? A PRO 3   
4   1 Y 1 A SER 4   ? A SER 4   
5   1 Y 1 A PRO 5   ? A PRO 5   
6   1 Y 1 A ALA 6   ? A ALA 6   
7   1 Y 1 A ALA 7   ? A ALA 7   
8   1 Y 1 A GLY 8   ? A GLY 8   
9   1 Y 1 A GLY 9   ? A GLY 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A GLU 11  ? A GLU 11  
12  1 Y 1 A THR 12  ? A THR 12  
13  1 Y 1 A THR 13  ? A THR 13  
14  1 Y 1 A ARG 14  ? A ARG 14  
15  1 Y 1 A LEU 15  ? A LEU 15  
16  1 Y 1 A VAL 16  ? A VAL 16  
17  1 Y 1 A SER 17  ? A SER 17  
18  1 Y 1 A PRO 18  ? A PRO 18  
19  1 Y 1 A ARG 19  ? A ARG 19  
20  1 Y 1 A ASP 20  ? A ASP 20  
21  1 Y 1 A ARG 21  ? A ARG 21  
22  1 Y 1 A GLY 22  ? A GLY 22  
23  1 Y 1 A GLY 23  ? A GLY 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A GLY 25  ? A GLY 25  
26  1 Y 1 A GLY 26  ? A GLY 26  
27  1 Y 1 A SER 27  ? A SER 27  
28  1 Y 1 A LEU 28  ? A LEU 28  
29  1 Y 1 A ARG 29  ? A ARG 29  
30  1 Y 1 A LEU 30  ? A LEU 30  
31  1 Y 1 A LYS 31  ? A LYS 31  
32  1 Y 1 A SER 32  ? A SER 32  
33  1 Y 1 A LEU 33  ? A LEU 33  
34  1 Y 1 A PHE 34  ? A PHE 34  
35  1 Y 1 A THR 35  ? A THR 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A PRO 37  ? A PRO 37  
38  1 Y 1 A SER 38  ? A SER 38  
39  1 Y 1 A GLU 39  ? A GLU 39  
40  1 Y 1 A PRO 40  ? A PRO 40  
41  1 Y 1 A LEU 41  ? A LEU 41  
42  1 Y 1 A PRO 42  ? A PRO 42  
43  1 Y 1 A GLU 43  ? A GLU 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A SER 45  ? A SER 45  
46  1 Y 1 A LYS 46  ? A LYS 46  
47  1 Y 1 A PRO 47  ? A PRO 47  
48  1 Y 1 A VAL 48  ? A VAL 48  
49  1 Y 1 A GLU 49  ? A GLU 49  
50  1 Y 1 A MET 50  ? A MET 50  
51  1 Y 1 A PRO 51  ? A PRO 51  
52  1 Y 1 A PHE 52  ? A PHE 52  
53  1 Y 1 A HIS 53  ? A HIS 53  
54  1 Y 1 A GLY 202 ? A GLY 202 
55  1 Y 1 A PRO 203 ? A PRO 203 
56  1 Y 1 A PRO 204 ? A PRO 204 
57  1 Y 1 A HIS 205 ? A HIS 205 
58  1 Y 1 A SER 206 ? A SER 206 
59  1 Y 1 A HIS 207 ? A HIS 207 
60  1 Y 1 A GLY 208 ? A GLY 208 
61  1 Y 1 A SER 209 ? A SER 209 
62  1 Y 1 A ARG 210 ? A ARG 210 
63  1 Y 1 A GLY 211 ? A GLY 211 
64  1 Y 1 A ALA 212 ? A ALA 212 
65  1 Y 1 A GLU 213 ? A GLU 213 
66  1 Y 1 A TYR 214 ? A TYR 214 
67  1 Y 1 A ALA 215 ? A ALA 215 
68  1 Y 1 A PRO 216 ? A PRO 216 
69  1 Y 1 A LEU 217 ? A LEU 217 
70  1 Y 1 A GLU 218 ? A GLU 218 
71  1 Y 1 A GLU 219 ? A GLU 219 
72  1 Y 1 A GLY 220 ? A GLY 220 
73  1 Y 1 A PRO 221 ? A PRO 221 
74  1 Y 1 A GLU 222 ? A GLU 222 
75  1 Y 1 A GLU 223 ? A GLU 223 
76  1 Y 1 A PRO 224 ? A PRO 224 
77  1 Y 1 A LEU 225 ? A LEU 225 
78  1 Y 1 A PRO 226 ? A PRO 226 
79  1 Y 1 A LEU 227 ? A LEU 227 
80  1 Y 1 A GLY 228 ? A GLY 228 
81  1 Y 1 A ASN 229 ? A ASN 229 
82  1 Y 1 A GLY 389 ? A GLY 389 
83  1 Y 1 A SER 390 ? A SER 390 
84  1 Y 1 A ILE 391 ? A ILE 391 
85  1 Y 1 A GLU 392 ? A GLU 392 
86  1 Y 1 A GLY 393 ? A GLY 393 
87  1 Y 1 A ARG 394 ? A ARG 394 
88  1 Y 1 A ILE 395 ? A ILE 395 
89  1 Y 1 A VAL 396 ? A VAL 396 
90  1 Y 1 A LYS 397 ? A LYS 397 
91  1 Y 1 A ASP 398 ? A ASP 398 
92  1 Y 1 A TYR 399 ? A TYR 399 
93  1 Y 1 A LYS 400 ? A LYS 400 
94  1 Y 1 A ASP 401 ? A ASP 401 
95  1 Y 1 A ASP 402 ? A ASP 402 
96  1 Y 1 A ASP 403 ? A ASP 403 
97  1 Y 1 A ASP 404 ? A ASP 404 
98  1 Y 1 A LYS 405 ? A LYS 405 
99  1 Y 1 B MET 1   ? B MET 1   
100 1 Y 1 B GLU 2   ? B GLU 2   
101 1 Y 1 B PRO 3   ? B PRO 3   
102 1 Y 1 B SER 4   ? B SER 4   
103 1 Y 1 B PRO 5   ? B PRO 5   
104 1 Y 1 B ALA 6   ? B ALA 6   
105 1 Y 1 B ALA 7   ? B ALA 7   
106 1 Y 1 B GLY 8   ? B GLY 8   
107 1 Y 1 B GLY 9   ? B GLY 9   
108 1 Y 1 B LEU 10  ? B LEU 10  
109 1 Y 1 B GLU 11  ? B GLU 11  
110 1 Y 1 B THR 12  ? B THR 12  
111 1 Y 1 B THR 13  ? B THR 13  
112 1 Y 1 B ARG 14  ? B ARG 14  
113 1 Y 1 B LEU 15  ? B LEU 15  
114 1 Y 1 B VAL 16  ? B VAL 16  
115 1 Y 1 B SER 17  ? B SER 17  
116 1 Y 1 B PRO 18  ? B PRO 18  
117 1 Y 1 B ARG 19  ? B ARG 19  
118 1 Y 1 B ASP 20  ? B ASP 20  
119 1 Y 1 B ARG 21  ? B ARG 21  
120 1 Y 1 B GLY 22  ? B GLY 22  
121 1 Y 1 B GLY 23  ? B GLY 23  
122 1 Y 1 B ALA 24  ? B ALA 24  
123 1 Y 1 B GLY 25  ? B GLY 25  
124 1 Y 1 B GLY 26  ? B GLY 26  
125 1 Y 1 B SER 27  ? B SER 27  
126 1 Y 1 B LEU 28  ? B LEU 28  
127 1 Y 1 B ARG 29  ? B ARG 29  
128 1 Y 1 B LEU 30  ? B LEU 30  
129 1 Y 1 B LYS 31  ? B LYS 31  
130 1 Y 1 B SER 32  ? B SER 32  
131 1 Y 1 B LEU 33  ? B LEU 33  
132 1 Y 1 B PHE 34  ? B PHE 34  
133 1 Y 1 B THR 35  ? B THR 35  
134 1 Y 1 B GLU 36  ? B GLU 36  
135 1 Y 1 B PRO 37  ? B PRO 37  
136 1 Y 1 B SER 38  ? B SER 38  
137 1 Y 1 B GLU 39  ? B GLU 39  
138 1 Y 1 B PRO 40  ? B PRO 40  
139 1 Y 1 B LEU 41  ? B LEU 41  
140 1 Y 1 B PRO 42  ? B PRO 42  
141 1 Y 1 B GLU 43  ? B GLU 43  
142 1 Y 1 B GLU 44  ? B GLU 44  
143 1 Y 1 B SER 45  ? B SER 45  
144 1 Y 1 B LYS 46  ? B LYS 46  
145 1 Y 1 B PRO 47  ? B PRO 47  
146 1 Y 1 B VAL 48  ? B VAL 48  
147 1 Y 1 B GLU 49  ? B GLU 49  
148 1 Y 1 B MET 50  ? B MET 50  
149 1 Y 1 B PRO 51  ? B PRO 51  
150 1 Y 1 B PHE 52  ? B PHE 52  
151 1 Y 1 B HIS 53  ? B HIS 53  
152 1 Y 1 B GLY 202 ? B GLY 202 
153 1 Y 1 B PRO 203 ? B PRO 203 
154 1 Y 1 B PRO 204 ? B PRO 204 
155 1 Y 1 B HIS 205 ? B HIS 205 
156 1 Y 1 B SER 206 ? B SER 206 
157 1 Y 1 B HIS 207 ? B HIS 207 
158 1 Y 1 B GLY 208 ? B GLY 208 
159 1 Y 1 B SER 209 ? B SER 209 
160 1 Y 1 B ARG 210 ? B ARG 210 
161 1 Y 1 B GLY 211 ? B GLY 211 
162 1 Y 1 B ALA 212 ? B ALA 212 
163 1 Y 1 B GLU 213 ? B GLU 213 
164 1 Y 1 B TYR 214 ? B TYR 214 
165 1 Y 1 B ALA 215 ? B ALA 215 
166 1 Y 1 B PRO 216 ? B PRO 216 
167 1 Y 1 B LEU 217 ? B LEU 217 
168 1 Y 1 B GLU 218 ? B GLU 218 
169 1 Y 1 B GLU 219 ? B GLU 219 
170 1 Y 1 B GLY 220 ? B GLY 220 
171 1 Y 1 B PRO 221 ? B PRO 221 
172 1 Y 1 B GLU 222 ? B GLU 222 
173 1 Y 1 B GLU 223 ? B GLU 223 
174 1 Y 1 B PRO 224 ? B PRO 224 
175 1 Y 1 B LEU 225 ? B LEU 225 
176 1 Y 1 B PRO 226 ? B PRO 226 
177 1 Y 1 B LEU 227 ? B LEU 227 
178 1 Y 1 B GLY 228 ? B GLY 228 
179 1 Y 1 B ASN 229 ? B ASN 229 
180 1 Y 1 B GLY 389 ? B GLY 389 
181 1 Y 1 B SER 390 ? B SER 390 
182 1 Y 1 B ILE 391 ? B ILE 391 
183 1 Y 1 B GLU 392 ? B GLU 392 
184 1 Y 1 B GLY 393 ? B GLY 393 
185 1 Y 1 B ARG 394 ? B ARG 394 
186 1 Y 1 B ILE 395 ? B ILE 395 
187 1 Y 1 B VAL 396 ? B VAL 396 
188 1 Y 1 B LYS 397 ? B LYS 397 
189 1 Y 1 B ASP 398 ? B ASP 398 
190 1 Y 1 B TYR 399 ? B TYR 399 
191 1 Y 1 B LYS 400 ? B LYS 400 
192 1 Y 1 B ASP 401 ? B ASP 401 
193 1 Y 1 B ASP 402 ? B ASP 402 
194 1 Y 1 B ASP 403 ? B ASP 403 
195 1 Y 1 B ASP 404 ? B ASP 404 
196 1 Y 1 B LYS 405 ? B LYS 405 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
AV0 C1   C  N R 74  
AV0 O1   O  N N 75  
AV0 C2   C  N R 76  
AV0 O2   O  N N 77  
AV0 C3   C  N R 78  
AV0 O3   O  N N 79  
AV0 C4   C  N S 80  
AV0 O4   O  N N 81  
AV0 C5   C  N R 82  
AV0 O5   O  N N 83  
AV0 C6   C  N N 84  
AV0 O6   O  N N 85  
AV0 CAA  C  N N 86  
AV0 CAB  C  N N 87  
AV0 OAI  O  N N 88  
AV0 OAJ  O  N N 89  
AV0 OAL  O  N N 90  
AV0 OAN  O  N N 91  
AV0 OAP  O  N N 92  
AV0 OAQ  O  N N 93  
AV0 OAR  O  N N 94  
AV0 OAS  O  N N 95  
AV0 OAT  O  N N 96  
AV0 OAU  O  N N 97  
AV0 OAV  O  N N 98  
AV0 CAW  C  N N 99  
AV0 CAX  C  N N 100 
AV0 CAY  C  N N 101 
AV0 CAZ  C  N N 102 
AV0 CBA  C  N N 103 
AV0 CBB  C  N N 104 
AV0 CBC  C  N N 105 
AV0 CBD  C  N N 106 
AV0 CBE  C  N N 107 
AV0 CBF  C  N N 108 
AV0 CBG  C  N N 109 
AV0 CBH  C  N N 110 
AV0 CBI  C  N N 111 
AV0 CBJ  C  N N 112 
AV0 CBK  C  N N 113 
AV0 CBL  C  N N 114 
AV0 CBM  C  N N 115 
AV0 CBN  C  N N 116 
AV0 CBP  C  N N 117 
AV0 CBQ  C  N N 118 
AV0 CBR  C  N N 119 
AV0 CBS  C  N N 120 
AV0 CBT  C  N N 121 
AV0 OBV  O  N N 122 
AV0 OBX  O  N N 123 
AV0 OBY  O  N N 124 
AV0 OBZ  O  N N 125 
AV0 OCB  O  N N 126 
AV0 CCC  C  N R 127 
AV0 CCD  C  N R 128 
AV0 CCF  C  N R 129 
AV0 CCH  C  N R 130 
AV0 CCJ  C  N R 131 
AV0 CCL  C  N R 132 
AV0 CCM  C  N N 133 
AV0 CCN  C  N S 134 
AV0 CCO  C  N S 135 
AV0 CCQ  C  N S 136 
AV0 CCR  C  N R 137 
AV0 CCS  C  N R 138 
AV0 CCT  C  N S 139 
AV0 CCU  C  N S 140 
AV0 CCV  C  N R 141 
AV0 CCW  C  N R 142 
AV0 H1   H  N N 143 
AV0 H2   H  N N 144 
AV0 H3   H  N N 145 
AV0 H4   H  N N 146 
AV0 H5   H  N N 147 
AV0 H6   H  N N 148 
AV0 H7   H  N N 149 
AV0 H8   H  N N 150 
AV0 H9   H  N N 151 
AV0 H10  H  N N 152 
AV0 H11  H  N N 153 
AV0 H12  H  N N 154 
AV0 H13  H  N N 155 
AV0 H14  H  N N 156 
AV0 H15  H  N N 157 
AV0 H16  H  N N 158 
AV0 H17  H  N N 159 
AV0 H18  H  N N 160 
AV0 H19  H  N N 161 
AV0 H20  H  N N 162 
AV0 H21  H  N N 163 
AV0 H22  H  N N 164 
AV0 H23  H  N N 165 
AV0 H24  H  N N 166 
AV0 H25  H  N N 167 
AV0 H26  H  N N 168 
AV0 H27  H  N N 169 
AV0 H28  H  N N 170 
AV0 H29  H  N N 171 
AV0 H30  H  N N 172 
AV0 H31  H  N N 173 
AV0 H32  H  N N 174 
AV0 H33  H  N N 175 
AV0 H34  H  N N 176 
AV0 H35  H  N N 177 
AV0 H36  H  N N 178 
AV0 H37  H  N N 179 
AV0 H38  H  N N 180 
AV0 H39  H  N N 181 
AV0 H40  H  N N 182 
AV0 H41  H  N N 183 
AV0 H42  H  N N 184 
AV0 H43  H  N N 185 
AV0 H44  H  N N 186 
AV0 H45  H  N N 187 
AV0 H46  H  N N 188 
AV0 H47  H  N N 189 
AV0 H48  H  N N 190 
AV0 H49  H  N N 191 
AV0 H50  H  N N 192 
AV0 H51  H  N N 193 
AV0 H52  H  N N 194 
AV0 H53  H  N N 195 
AV0 H54  H  N N 196 
AV0 H55  H  N N 197 
AV0 H56  H  N N 198 
AV0 H57  H  N N 199 
AV0 H58  H  N N 200 
AV0 H59  H  N N 201 
AV0 H60  H  N N 202 
AV0 H61  H  N N 203 
AV0 H62  H  N N 204 
AV0 H63  H  N N 205 
AV0 H64  H  N N 206 
AV0 H65  H  N N 207 
AV0 H66  H  N N 208 
AV0 H67  H  N N 209 
AV0 H68  H  N N 210 
AV0 H69  H  N N 211 
AV0 H70  H  N N 212 
AV0 H71  H  N N 213 
AV0 H72  H  N N 214 
AV0 H73  H  N N 215 
AV0 H74  H  N N 216 
AV0 H75  H  N N 217 
AV0 H76  H  N N 218 
AV0 H77  H  N N 219 
AV0 H78  H  N N 220 
AV0 H79  H  N N 221 
AV0 H80  H  N N 222 
AV0 H81  H  N N 223 
AV0 H82  H  N N 224 
AV0 H83  H  N N 225 
AV0 H84  H  N N 226 
AV0 H85  H  N N 227 
AV0 H86  H  N N 228 
AV0 H87  H  N N 229 
AV0 H88  H  N N 230 
CYS N    N  N N 231 
CYS CA   C  N R 232 
CYS C    C  N N 233 
CYS O    O  N N 234 
CYS CB   C  N N 235 
CYS SG   S  N N 236 
CYS OXT  O  N N 237 
CYS H    H  N N 238 
CYS H2   H  N N 239 
CYS HA   H  N N 240 
CYS HB2  H  N N 241 
CYS HB3  H  N N 242 
CYS HG   H  N N 243 
CYS HXT  H  N N 244 
GLN N    N  N N 245 
GLN CA   C  N S 246 
GLN C    C  N N 247 
GLN O    O  N N 248 
GLN CB   C  N N 249 
GLN CG   C  N N 250 
GLN CD   C  N N 251 
GLN OE1  O  N N 252 
GLN NE2  N  N N 253 
GLN OXT  O  N N 254 
GLN H    H  N N 255 
GLN H2   H  N N 256 
GLN HA   H  N N 257 
GLN HB2  H  N N 258 
GLN HB3  H  N N 259 
GLN HG2  H  N N 260 
GLN HG3  H  N N 261 
GLN HE21 H  N N 262 
GLN HE22 H  N N 263 
GLN HXT  H  N N 264 
GLU N    N  N N 265 
GLU CA   C  N S 266 
GLU C    C  N N 267 
GLU O    O  N N 268 
GLU CB   C  N N 269 
GLU CG   C  N N 270 
GLU CD   C  N N 271 
GLU OE1  O  N N 272 
GLU OE2  O  N N 273 
GLU OXT  O  N N 274 
GLU H    H  N N 275 
GLU H2   H  N N 276 
GLU HA   H  N N 277 
GLU HB2  H  N N 278 
GLU HB3  H  N N 279 
GLU HG2  H  N N 280 
GLU HG3  H  N N 281 
GLU HE2  H  N N 282 
GLU HXT  H  N N 283 
GLY N    N  N N 284 
GLY CA   C  N N 285 
GLY C    C  N N 286 
GLY O    O  N N 287 
GLY OXT  O  N N 288 
GLY H    H  N N 289 
GLY H2   H  N N 290 
GLY HA2  H  N N 291 
GLY HA3  H  N N 292 
GLY HXT  H  N N 293 
HIS N    N  N N 294 
HIS CA   C  N S 295 
HIS C    C  N N 296 
HIS O    O  N N 297 
HIS CB   C  N N 298 
HIS CG   C  Y N 299 
HIS ND1  N  Y N 300 
HIS CD2  C  Y N 301 
HIS CE1  C  Y N 302 
HIS NE2  N  Y N 303 
HIS OXT  O  N N 304 
HIS H    H  N N 305 
HIS H2   H  N N 306 
HIS HA   H  N N 307 
HIS HB2  H  N N 308 
HIS HB3  H  N N 309 
HIS HD1  H  N N 310 
HIS HD2  H  N N 311 
HIS HE1  H  N N 312 
HIS HE2  H  N N 313 
HIS HXT  H  N N 314 
ILE N    N  N N 315 
ILE CA   C  N S 316 
ILE C    C  N N 317 
ILE O    O  N N 318 
ILE CB   C  N S 319 
ILE CG1  C  N N 320 
ILE CG2  C  N N 321 
ILE CD1  C  N N 322 
ILE OXT  O  N N 323 
ILE H    H  N N 324 
ILE H2   H  N N 325 
ILE HA   H  N N 326 
ILE HB   H  N N 327 
ILE HG12 H  N N 328 
ILE HG13 H  N N 329 
ILE HG21 H  N N 330 
ILE HG22 H  N N 331 
ILE HG23 H  N N 332 
ILE HD11 H  N N 333 
ILE HD12 H  N N 334 
ILE HD13 H  N N 335 
ILE HXT  H  N N 336 
LEU N    N  N N 337 
LEU CA   C  N S 338 
LEU C    C  N N 339 
LEU O    O  N N 340 
LEU CB   C  N N 341 
LEU CG   C  N N 342 
LEU CD1  C  N N 343 
LEU CD2  C  N N 344 
LEU OXT  O  N N 345 
LEU H    H  N N 346 
LEU H2   H  N N 347 
LEU HA   H  N N 348 
LEU HB2  H  N N 349 
LEU HB3  H  N N 350 
LEU HG   H  N N 351 
LEU HD11 H  N N 352 
LEU HD12 H  N N 353 
LEU HD13 H  N N 354 
LEU HD21 H  N N 355 
LEU HD22 H  N N 356 
LEU HD23 H  N N 357 
LEU HXT  H  N N 358 
LYS N    N  N N 359 
LYS CA   C  N S 360 
LYS C    C  N N 361 
LYS O    O  N N 362 
LYS CB   C  N N 363 
LYS CG   C  N N 364 
LYS CD   C  N N 365 
LYS CE   C  N N 366 
LYS NZ   N  N N 367 
LYS OXT  O  N N 368 
LYS H    H  N N 369 
LYS H2   H  N N 370 
LYS HA   H  N N 371 
LYS HB2  H  N N 372 
LYS HB3  H  N N 373 
LYS HG2  H  N N 374 
LYS HG3  H  N N 375 
LYS HD2  H  N N 376 
LYS HD3  H  N N 377 
LYS HE2  H  N N 378 
LYS HE3  H  N N 379 
LYS HZ1  H  N N 380 
LYS HZ2  H  N N 381 
LYS HZ3  H  N N 382 
LYS HXT  H  N N 383 
MET N    N  N N 384 
MET CA   C  N S 385 
MET C    C  N N 386 
MET O    O  N N 387 
MET CB   C  N N 388 
MET CG   C  N N 389 
MET SD   S  N N 390 
MET CE   C  N N 391 
MET OXT  O  N N 392 
MET H    H  N N 393 
MET H2   H  N N 394 
MET HA   H  N N 395 
MET HB2  H  N N 396 
MET HB3  H  N N 397 
MET HG2  H  N N 398 
MET HG3  H  N N 399 
MET HE1  H  N N 400 
MET HE2  H  N N 401 
MET HE3  H  N N 402 
MET HXT  H  N N 403 
PHE N    N  N N 404 
PHE CA   C  N S 405 
PHE C    C  N N 406 
PHE O    O  N N 407 
PHE CB   C  N N 408 
PHE CG   C  Y N 409 
PHE CD1  C  Y N 410 
PHE CD2  C  Y N 411 
PHE CE1  C  Y N 412 
PHE CE2  C  Y N 413 
PHE CZ   C  Y N 414 
PHE OXT  O  N N 415 
PHE H    H  N N 416 
PHE H2   H  N N 417 
PHE HA   H  N N 418 
PHE HB2  H  N N 419 
PHE HB3  H  N N 420 
PHE HD1  H  N N 421 
PHE HD2  H  N N 422 
PHE HE1  H  N N 423 
PHE HE2  H  N N 424 
PHE HZ   H  N N 425 
PHE HXT  H  N N 426 
PRO N    N  N N 427 
PRO CA   C  N S 428 
PRO C    C  N N 429 
PRO O    O  N N 430 
PRO CB   C  N N 431 
PRO CG   C  N N 432 
PRO CD   C  N N 433 
PRO OXT  O  N N 434 
PRO H    H  N N 435 
PRO HA   H  N N 436 
PRO HB2  H  N N 437 
PRO HB3  H  N N 438 
PRO HG2  H  N N 439 
PRO HG3  H  N N 440 
PRO HD2  H  N N 441 
PRO HD3  H  N N 442 
PRO HXT  H  N N 443 
SER N    N  N N 444 
SER CA   C  N S 445 
SER C    C  N N 446 
SER O    O  N N 447 
SER CB   C  N N 448 
SER OG   O  N N 449 
SER OXT  O  N N 450 
SER H    H  N N 451 
SER H2   H  N N 452 
SER HA   H  N N 453 
SER HB2  H  N N 454 
SER HB3  H  N N 455 
SER HG   H  N N 456 
SER HXT  H  N N 457 
THR N    N  N N 458 
THR CA   C  N S 459 
THR C    C  N N 460 
THR O    O  N N 461 
THR CB   C  N R 462 
THR OG1  O  N N 463 
THR CG2  C  N N 464 
THR OXT  O  N N 465 
THR H    H  N N 466 
THR H2   H  N N 467 
THR HA   H  N N 468 
THR HB   H  N N 469 
THR HG1  H  N N 470 
THR HG21 H  N N 471 
THR HG22 H  N N 472 
THR HG23 H  N N 473 
THR HXT  H  N N 474 
TRP N    N  N N 475 
TRP CA   C  N S 476 
TRP C    C  N N 477 
TRP O    O  N N 478 
TRP CB   C  N N 479 
TRP CG   C  Y N 480 
TRP CD1  C  Y N 481 
TRP CD2  C  Y N 482 
TRP NE1  N  Y N 483 
TRP CE2  C  Y N 484 
TRP CE3  C  Y N 485 
TRP CZ2  C  Y N 486 
TRP CZ3  C  Y N 487 
TRP CH2  C  Y N 488 
TRP OXT  O  N N 489 
TRP H    H  N N 490 
TRP H2   H  N N 491 
TRP HA   H  N N 492 
TRP HB2  H  N N 493 
TRP HB3  H  N N 494 
TRP HD1  H  N N 495 
TRP HE1  H  N N 496 
TRP HE3  H  N N 497 
TRP HZ2  H  N N 498 
TRP HZ3  H  N N 499 
TRP HH2  H  N N 500 
TRP HXT  H  N N 501 
TYR N    N  N N 502 
TYR CA   C  N S 503 
TYR C    C  N N 504 
TYR O    O  N N 505 
TYR CB   C  N N 506 
TYR CG   C  Y N 507 
TYR CD1  C  Y N 508 
TYR CD2  C  Y N 509 
TYR CE1  C  Y N 510 
TYR CE2  C  Y N 511 
TYR CZ   C  Y N 512 
TYR OH   O  N N 513 
TYR OXT  O  N N 514 
TYR H    H  N N 515 
TYR H2   H  N N 516 
TYR HA   H  N N 517 
TYR HB2  H  N N 518 
TYR HB3  H  N N 519 
TYR HD1  H  N N 520 
TYR HD2  H  N N 521 
TYR HE1  H  N N 522 
TYR HE2  H  N N 523 
TYR HH   H  N N 524 
TYR HXT  H  N N 525 
VAL N    N  N N 526 
VAL CA   C  N S 527 
VAL C    C  N N 528 
VAL O    O  N N 529 
VAL CB   C  N N 530 
VAL CG1  C  N N 531 
VAL CG2  C  N N 532 
VAL OXT  O  N N 533 
VAL H    H  N N 534 
VAL H2   H  N N 535 
VAL HA   H  N N 536 
VAL HB   H  N N 537 
VAL HG11 H  N N 538 
VAL HG12 H  N N 539 
VAL HG13 H  N N 540 
VAL HG21 H  N N 541 
VAL HG22 H  N N 542 
VAL HG23 H  N N 543 
VAL HXT  H  N N 544 
ZN  ZN   ZN N N 545 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
AV0 CAB CAX  sing N N 70  
AV0 CAX CAZ  sing N N 71  
AV0 CAA CAW  sing N N 72  
AV0 CAZ CBB  sing N N 73  
AV0 CAW CAY  sing N N 74  
AV0 CBB CBD  sing N N 75  
AV0 CAY CBA  sing N N 76  
AV0 CBD CBF  sing N N 77  
AV0 CBA CBC  sing N N 78  
AV0 CBC CBE  sing N N 79  
AV0 CBF CBH  sing N N 80  
AV0 CBE CBG  sing N N 81  
AV0 CBH CBJ  sing N N 82  
AV0 OAJ CBN  sing N N 83  
AV0 OAR CCO  sing N N 84  
AV0 CBG CBI  sing N N 85  
AV0 CBJ CBL  sing N N 86  
AV0 CBL CBR  sing N N 87  
AV0 CBP OAL  sing N N 88  
AV0 CBP CCF  sing N N 89  
AV0 CBN CCD  sing N N 90  
AV0 CCO CCD  sing N N 91  
AV0 CCO CCU  sing N N 92  
AV0 CBI CBK  sing N N 93  
AV0 OAT CCU  sing N N 94  
AV0 CCD OBZ  sing N N 95  
AV0 CCU CCW  sing N N 96  
AV0 CBQ CBK  sing N N 97  
AV0 CBQ CCM  sing N N 98  
AV0 CCF OBX  sing N N 99  
AV0 CCF CCQ  sing N N 100 
AV0 CBR CCM  sing N N 101 
AV0 CBT CCM  sing N N 102 
AV0 CBT OBV  sing N N 103 
AV0 OBX CCJ  sing N N 104 
AV0 CCM CBS  sing N N 105 
AV0 OBZ CCS  sing N N 106 
AV0 OCB CCQ  sing N N 107 
AV0 OCB CCS  sing N N 108 
AV0 CCW CCS  sing N N 109 
AV0 CCW OAV  sing N N 110 
AV0 CCQ CCH  sing N N 111 
AV0 CCJ OBV  sing N N 112 
AV0 CCJ CCL  sing N N 113 
AV0 CBS O1   sing N N 114 
AV0 O1  C1   sing N N 115 
AV0 CCH CCL  sing N N 116 
AV0 CCH OAN  sing N N 117 
AV0 CCL OAP  sing N N 118 
AV0 O2  C2   sing N N 119 
AV0 C1  C2   sing N N 120 
AV0 C1  O5   sing N N 121 
AV0 C2  C3   sing N N 122 
AV0 O5  C5   sing N N 123 
AV0 C3  O3   sing N N 124 
AV0 C3  C4   sing N N 125 
AV0 C5  C4   sing N N 126 
AV0 C5  C6   sing N N 127 
AV0 C4  O4   sing N N 128 
AV0 C6  O6   sing N N 129 
AV0 O4  CCR  sing N N 130 
AV0 CCR OBY  sing N N 131 
AV0 CCR CCV  sing N N 132 
AV0 OBY CCC  sing N N 133 
AV0 OAU CCV  sing N N 134 
AV0 CCV CCT  sing N N 135 
AV0 CCC CBM  sing N N 136 
AV0 CCC CCN  sing N N 137 
AV0 CBM OAI  sing N N 138 
AV0 CCT CCN  sing N N 139 
AV0 CCT OAS  sing N N 140 
AV0 CCN OAQ  sing N N 141 
AV0 C1  H1   sing N N 142 
AV0 C2  H2   sing N N 143 
AV0 O2  H3   sing N N 144 
AV0 C3  H4   sing N N 145 
AV0 O3  H5   sing N N 146 
AV0 C4  H6   sing N N 147 
AV0 C5  H7   sing N N 148 
AV0 C6  H8   sing N N 149 
AV0 C6  H9   sing N N 150 
AV0 O6  H10  sing N N 151 
AV0 CAA H11  sing N N 152 
AV0 CAA H12  sing N N 153 
AV0 CAA H13  sing N N 154 
AV0 CAB H14  sing N N 155 
AV0 CAB H15  sing N N 156 
AV0 CAB H16  sing N N 157 
AV0 OAI H17  sing N N 158 
AV0 OAJ H18  sing N N 159 
AV0 OAL H19  sing N N 160 
AV0 OAN H20  sing N N 161 
AV0 OAP H21  sing N N 162 
AV0 OAQ H22  sing N N 163 
AV0 OAR H23  sing N N 164 
AV0 OAS H24  sing N N 165 
AV0 OAT H25  sing N N 166 
AV0 OAU H26  sing N N 167 
AV0 OAV H27  sing N N 168 
AV0 CAW H28  sing N N 169 
AV0 CAW H29  sing N N 170 
AV0 CAX H30  sing N N 171 
AV0 CAX H31  sing N N 172 
AV0 CAY H32  sing N N 173 
AV0 CAY H33  sing N N 174 
AV0 CAZ H34  sing N N 175 
AV0 CAZ H35  sing N N 176 
AV0 CBA H36  sing N N 177 
AV0 CBA H37  sing N N 178 
AV0 CBB H38  sing N N 179 
AV0 CBB H39  sing N N 180 
AV0 CBC H40  sing N N 181 
AV0 CBC H41  sing N N 182 
AV0 CBD H42  sing N N 183 
AV0 CBD H43  sing N N 184 
AV0 CBE H44  sing N N 185 
AV0 CBE H45  sing N N 186 
AV0 CBF H46  sing N N 187 
AV0 CBF H47  sing N N 188 
AV0 CBG H48  sing N N 189 
AV0 CBG H49  sing N N 190 
AV0 CBH H50  sing N N 191 
AV0 CBH H51  sing N N 192 
AV0 CBI H52  sing N N 193 
AV0 CBI H53  sing N N 194 
AV0 CBJ H54  sing N N 195 
AV0 CBJ H55  sing N N 196 
AV0 CBK H56  sing N N 197 
AV0 CBK H57  sing N N 198 
AV0 CBL H58  sing N N 199 
AV0 CBL H59  sing N N 200 
AV0 CBM H60  sing N N 201 
AV0 CBM H61  sing N N 202 
AV0 CBN H62  sing N N 203 
AV0 CBN H63  sing N N 204 
AV0 CBP H64  sing N N 205 
AV0 CBP H65  sing N N 206 
AV0 CBQ H66  sing N N 207 
AV0 CBQ H67  sing N N 208 
AV0 CBR H68  sing N N 209 
AV0 CBR H69  sing N N 210 
AV0 CBS H70  sing N N 211 
AV0 CBS H71  sing N N 212 
AV0 CBT H72  sing N N 213 
AV0 CBT H73  sing N N 214 
AV0 CCC H74  sing N N 215 
AV0 CCD H75  sing N N 216 
AV0 CCF H76  sing N N 217 
AV0 CCH H77  sing N N 218 
AV0 CCJ H78  sing N N 219 
AV0 CCL H79  sing N N 220 
AV0 CCN H80  sing N N 221 
AV0 CCO H81  sing N N 222 
AV0 CCQ H82  sing N N 223 
AV0 CCR H83  sing N N 224 
AV0 CCS H84  sing N N 225 
AV0 CCT H85  sing N N 226 
AV0 CCU H86  sing N N 227 
AV0 CCV H87  sing N N 228 
AV0 CCW H88  sing N N 229 
CYS N   CA   sing N N 230 
CYS N   H    sing N N 231 
CYS N   H2   sing N N 232 
CYS CA  C    sing N N 233 
CYS CA  CB   sing N N 234 
CYS CA  HA   sing N N 235 
CYS C   O    doub N N 236 
CYS C   OXT  sing N N 237 
CYS CB  SG   sing N N 238 
CYS CB  HB2  sing N N 239 
CYS CB  HB3  sing N N 240 
CYS SG  HG   sing N N 241 
CYS OXT HXT  sing N N 242 
GLN N   CA   sing N N 243 
GLN N   H    sing N N 244 
GLN N   H2   sing N N 245 
GLN CA  C    sing N N 246 
GLN CA  CB   sing N N 247 
GLN CA  HA   sing N N 248 
GLN C   O    doub N N 249 
GLN C   OXT  sing N N 250 
GLN CB  CG   sing N N 251 
GLN CB  HB2  sing N N 252 
GLN CB  HB3  sing N N 253 
GLN CG  CD   sing N N 254 
GLN CG  HG2  sing N N 255 
GLN CG  HG3  sing N N 256 
GLN CD  OE1  doub N N 257 
GLN CD  NE2  sing N N 258 
GLN NE2 HE21 sing N N 259 
GLN NE2 HE22 sing N N 260 
GLN OXT HXT  sing N N 261 
GLU N   CA   sing N N 262 
GLU N   H    sing N N 263 
GLU N   H2   sing N N 264 
GLU CA  C    sing N N 265 
GLU CA  CB   sing N N 266 
GLU CA  HA   sing N N 267 
GLU C   O    doub N N 268 
GLU C   OXT  sing N N 269 
GLU CB  CG   sing N N 270 
GLU CB  HB2  sing N N 271 
GLU CB  HB3  sing N N 272 
GLU CG  CD   sing N N 273 
GLU CG  HG2  sing N N 274 
GLU CG  HG3  sing N N 275 
GLU CD  OE1  doub N N 276 
GLU CD  OE2  sing N N 277 
GLU OE2 HE2  sing N N 278 
GLU OXT HXT  sing N N 279 
GLY N   CA   sing N N 280 
GLY N   H    sing N N 281 
GLY N   H2   sing N N 282 
GLY CA  C    sing N N 283 
GLY CA  HA2  sing N N 284 
GLY CA  HA3  sing N N 285 
GLY C   O    doub N N 286 
GLY C   OXT  sing N N 287 
GLY OXT HXT  sing N N 288 
HIS N   CA   sing N N 289 
HIS N   H    sing N N 290 
HIS N   H2   sing N N 291 
HIS CA  C    sing N N 292 
HIS CA  CB   sing N N 293 
HIS CA  HA   sing N N 294 
HIS C   O    doub N N 295 
HIS C   OXT  sing N N 296 
HIS CB  CG   sing N N 297 
HIS CB  HB2  sing N N 298 
HIS CB  HB3  sing N N 299 
HIS CG  ND1  sing Y N 300 
HIS CG  CD2  doub Y N 301 
HIS ND1 CE1  doub Y N 302 
HIS ND1 HD1  sing N N 303 
HIS CD2 NE2  sing Y N 304 
HIS CD2 HD2  sing N N 305 
HIS CE1 NE2  sing Y N 306 
HIS CE1 HE1  sing N N 307 
HIS NE2 HE2  sing N N 308 
HIS OXT HXT  sing N N 309 
ILE N   CA   sing N N 310 
ILE N   H    sing N N 311 
ILE N   H2   sing N N 312 
ILE CA  C    sing N N 313 
ILE CA  CB   sing N N 314 
ILE CA  HA   sing N N 315 
ILE C   O    doub N N 316 
ILE C   OXT  sing N N 317 
ILE CB  CG1  sing N N 318 
ILE CB  CG2  sing N N 319 
ILE CB  HB   sing N N 320 
ILE CG1 CD1  sing N N 321 
ILE CG1 HG12 sing N N 322 
ILE CG1 HG13 sing N N 323 
ILE CG2 HG21 sing N N 324 
ILE CG2 HG22 sing N N 325 
ILE CG2 HG23 sing N N 326 
ILE CD1 HD11 sing N N 327 
ILE CD1 HD12 sing N N 328 
ILE CD1 HD13 sing N N 329 
ILE OXT HXT  sing N N 330 
LEU N   CA   sing N N 331 
LEU N   H    sing N N 332 
LEU N   H2   sing N N 333 
LEU CA  C    sing N N 334 
LEU CA  CB   sing N N 335 
LEU CA  HA   sing N N 336 
LEU C   O    doub N N 337 
LEU C   OXT  sing N N 338 
LEU CB  CG   sing N N 339 
LEU CB  HB2  sing N N 340 
LEU CB  HB3  sing N N 341 
LEU CG  CD1  sing N N 342 
LEU CG  CD2  sing N N 343 
LEU CG  HG   sing N N 344 
LEU CD1 HD11 sing N N 345 
LEU CD1 HD12 sing N N 346 
LEU CD1 HD13 sing N N 347 
LEU CD2 HD21 sing N N 348 
LEU CD2 HD22 sing N N 349 
LEU CD2 HD23 sing N N 350 
LEU OXT HXT  sing N N 351 
LYS N   CA   sing N N 352 
LYS N   H    sing N N 353 
LYS N   H2   sing N N 354 
LYS CA  C    sing N N 355 
LYS CA  CB   sing N N 356 
LYS CA  HA   sing N N 357 
LYS C   O    doub N N 358 
LYS C   OXT  sing N N 359 
LYS CB  CG   sing N N 360 
LYS CB  HB2  sing N N 361 
LYS CB  HB3  sing N N 362 
LYS CG  CD   sing N N 363 
LYS CG  HG2  sing N N 364 
LYS CG  HG3  sing N N 365 
LYS CD  CE   sing N N 366 
LYS CD  HD2  sing N N 367 
LYS CD  HD3  sing N N 368 
LYS CE  NZ   sing N N 369 
LYS CE  HE2  sing N N 370 
LYS CE  HE3  sing N N 371 
LYS NZ  HZ1  sing N N 372 
LYS NZ  HZ2  sing N N 373 
LYS NZ  HZ3  sing N N 374 
LYS OXT HXT  sing N N 375 
MET N   CA   sing N N 376 
MET N   H    sing N N 377 
MET N   H2   sing N N 378 
MET CA  C    sing N N 379 
MET CA  CB   sing N N 380 
MET CA  HA   sing N N 381 
MET C   O    doub N N 382 
MET C   OXT  sing N N 383 
MET CB  CG   sing N N 384 
MET CB  HB2  sing N N 385 
MET CB  HB3  sing N N 386 
MET CG  SD   sing N N 387 
MET CG  HG2  sing N N 388 
MET CG  HG3  sing N N 389 
MET SD  CE   sing N N 390 
MET CE  HE1  sing N N 391 
MET CE  HE2  sing N N 392 
MET CE  HE3  sing N N 393 
MET OXT HXT  sing N N 394 
PHE N   CA   sing N N 395 
PHE N   H    sing N N 396 
PHE N   H2   sing N N 397 
PHE CA  C    sing N N 398 
PHE CA  CB   sing N N 399 
PHE CA  HA   sing N N 400 
PHE C   O    doub N N 401 
PHE C   OXT  sing N N 402 
PHE CB  CG   sing N N 403 
PHE CB  HB2  sing N N 404 
PHE CB  HB3  sing N N 405 
PHE CG  CD1  doub Y N 406 
PHE CG  CD2  sing Y N 407 
PHE CD1 CE1  sing Y N 408 
PHE CD1 HD1  sing N N 409 
PHE CD2 CE2  doub Y N 410 
PHE CD2 HD2  sing N N 411 
PHE CE1 CZ   doub Y N 412 
PHE CE1 HE1  sing N N 413 
PHE CE2 CZ   sing Y N 414 
PHE CE2 HE2  sing N N 415 
PHE CZ  HZ   sing N N 416 
PHE OXT HXT  sing N N 417 
PRO N   CA   sing N N 418 
PRO N   CD   sing N N 419 
PRO N   H    sing N N 420 
PRO CA  C    sing N N 421 
PRO CA  CB   sing N N 422 
PRO CA  HA   sing N N 423 
PRO C   O    doub N N 424 
PRO C   OXT  sing N N 425 
PRO CB  CG   sing N N 426 
PRO CB  HB2  sing N N 427 
PRO CB  HB3  sing N N 428 
PRO CG  CD   sing N N 429 
PRO CG  HG2  sing N N 430 
PRO CG  HG3  sing N N 431 
PRO CD  HD2  sing N N 432 
PRO CD  HD3  sing N N 433 
PRO OXT HXT  sing N N 434 
SER N   CA   sing N N 435 
SER N   H    sing N N 436 
SER N   H2   sing N N 437 
SER CA  C    sing N N 438 
SER CA  CB   sing N N 439 
SER CA  HA   sing N N 440 
SER C   O    doub N N 441 
SER C   OXT  sing N N 442 
SER CB  OG   sing N N 443 
SER CB  HB2  sing N N 444 
SER CB  HB3  sing N N 445 
SER OG  HG   sing N N 446 
SER OXT HXT  sing N N 447 
THR N   CA   sing N N 448 
THR N   H    sing N N 449 
THR N   H2   sing N N 450 
THR CA  C    sing N N 451 
THR CA  CB   sing N N 452 
THR CA  HA   sing N N 453 
THR C   O    doub N N 454 
THR C   OXT  sing N N 455 
THR CB  OG1  sing N N 456 
THR CB  CG2  sing N N 457 
THR CB  HB   sing N N 458 
THR OG1 HG1  sing N N 459 
THR CG2 HG21 sing N N 460 
THR CG2 HG22 sing N N 461 
THR CG2 HG23 sing N N 462 
THR OXT HXT  sing N N 463 
TRP N   CA   sing N N 464 
TRP N   H    sing N N 465 
TRP N   H2   sing N N 466 
TRP CA  C    sing N N 467 
TRP CA  CB   sing N N 468 
TRP CA  HA   sing N N 469 
TRP C   O    doub N N 470 
TRP C   OXT  sing N N 471 
TRP CB  CG   sing N N 472 
TRP CB  HB2  sing N N 473 
TRP CB  HB3  sing N N 474 
TRP CG  CD1  doub Y N 475 
TRP CG  CD2  sing Y N 476 
TRP CD1 NE1  sing Y N 477 
TRP CD1 HD1  sing N N 478 
TRP CD2 CE2  doub Y N 479 
TRP CD2 CE3  sing Y N 480 
TRP NE1 CE2  sing Y N 481 
TRP NE1 HE1  sing N N 482 
TRP CE2 CZ2  sing Y N 483 
TRP CE3 CZ3  doub Y N 484 
TRP CE3 HE3  sing N N 485 
TRP CZ2 CH2  doub Y N 486 
TRP CZ2 HZ2  sing N N 487 
TRP CZ3 CH2  sing Y N 488 
TRP CZ3 HZ3  sing N N 489 
TRP CH2 HH2  sing N N 490 
TRP OXT HXT  sing N N 491 
TYR N   CA   sing N N 492 
TYR N   H    sing N N 493 
TYR N   H2   sing N N 494 
TYR CA  C    sing N N 495 
TYR CA  CB   sing N N 496 
TYR CA  HA   sing N N 497 
TYR C   O    doub N N 498 
TYR C   OXT  sing N N 499 
TYR CB  CG   sing N N 500 
TYR CB  HB2  sing N N 501 
TYR CB  HB3  sing N N 502 
TYR CG  CD1  doub Y N 503 
TYR CG  CD2  sing Y N 504 
TYR CD1 CE1  sing Y N 505 
TYR CD1 HD1  sing N N 506 
TYR CD2 CE2  doub Y N 507 
TYR CD2 HD2  sing N N 508 
TYR CE1 CZ   doub Y N 509 
TYR CE1 HE1  sing N N 510 
TYR CE2 CZ   sing Y N 511 
TYR CE2 HE2  sing N N 512 
TYR CZ  OH   sing N N 513 
TYR OH  HH   sing N N 514 
TYR OXT HXT  sing N N 515 
VAL N   CA   sing N N 516 
VAL N   H    sing N N 517 
VAL N   H2   sing N N 518 
VAL CA  C    sing N N 519 
VAL CA  CB   sing N N 520 
VAL CA  HA   sing N N 521 
VAL C   O    doub N N 522 
VAL C   OXT  sing N N 523 
VAL CB  CG1  sing N N 524 
VAL CB  CG2  sing N N 525 
VAL CB  HB   sing N N 526 
VAL CG1 HG11 sing N N 527 
VAL CG1 HG12 sing N N 528 
VAL CG1 HG13 sing N N 529 
VAL CG2 HG21 sing N N 530 
VAL CG2 HG22 sing N N 531 
VAL CG2 HG23 sing N N 532 
VAL OXT HXT  sing N N 533 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-12 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JJ1 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              'Cryo-EM structure of human ZnT3' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         68 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  1 ? 1 ?      ?            
MASKING                    ? 4  1 1 1 ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?            
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?            
'MODEL FITTING'            ? 8  1 1 1 ?      ?            
OTHER                      ? 9  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Ministry of Education, Culture, Sports, Science and Technology (Japan)' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           
;20K16274 and 22K07131 (H.I.); 22K15046 and 24K09349 (Z.Z.); 19H00976, 22H05184, and 23H00366 (T.S.); and 19H03164 and 22H02556 [U.O.)
;
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JJ1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . HIS A 1 54  ? 124.428 137.367 81.333  1.00 182.17 ? 54  HIS A N   1 
ATOM   2    C  CA  . HIS A 1 54  ? 125.267 137.403 82.524  1.00 185.32 ? 54  HIS A CA  1 
ATOM   3    C  C   . HIS A 1 54  ? 124.451 137.105 83.777  1.00 185.78 ? 54  HIS A C   1 
ATOM   4    O  O   . HIS A 1 54  ? 123.745 137.973 84.288  1.00 182.82 ? 54  HIS A O   1 
ATOM   5    C  CB  . HIS A 1 54  ? 125.956 138.764 82.653  1.00 183.53 ? 54  HIS A CB  1 
ATOM   6    C  CG  . HIS A 1 54  ? 127.075 138.788 83.648  1.00 182.96 ? 54  HIS A CG  1 
ATOM   7    N  ND1 . HIS A 1 54  ? 128.241 139.491 83.437  1.00 185.05 ? 54  HIS A ND1 1 
ATOM   8    C  CD2 . HIS A 1 54  ? 127.202 138.207 84.864  1.00 182.72 ? 54  HIS A CD2 1 
ATOM   9    C  CE1 . HIS A 1 54  ? 129.040 139.337 84.478  1.00 187.01 ? 54  HIS A CE1 1 
ATOM   10   N  NE2 . HIS A 1 54  ? 128.434 138.561 85.357  1.00 185.40 ? 54  HIS A NE2 1 
ATOM   11   N  N   . CYS A 1 55  ? 124.552 135.872 84.265  1.00 174.25 ? 55  CYS A N   1 
ATOM   12   C  CA  . CYS A 1 55  ? 123.897 135.510 85.513  1.00 171.14 ? 55  CYS A CA  1 
ATOM   13   C  C   . CYS A 1 55  ? 124.540 136.259 86.671  1.00 173.50 ? 55  CYS A C   1 
ATOM   14   O  O   . CYS A 1 55  ? 125.762 136.400 86.726  1.00 172.53 ? 55  CYS A O   1 
ATOM   15   C  CB  . CYS A 1 55  ? 123.988 134.004 85.749  1.00 169.99 ? 55  CYS A CB  1 
ATOM   16   S  SG  . CYS A 1 55  ? 125.634 133.414 86.229  1.00 173.09 ? 55  CYS A SG  1 
ATOM   17   N  N   . HIS A 1 56  ? 123.701 136.739 87.590  1.00 190.57 ? 56  HIS A N   1 
ATOM   18   C  CA  . HIS A 1 56  ? 123.997 137.518 88.801  1.00 191.25 ? 56  HIS A CA  1 
ATOM   19   C  C   . HIS A 1 56  ? 124.263 138.990 88.496  1.00 191.27 ? 56  HIS A C   1 
ATOM   20   O  O   . HIS A 1 56  ? 124.483 139.766 89.434  1.00 190.55 ? 56  HIS A O   1 
ATOM   21   C  CB  . HIS A 1 56  ? 125.146 136.919 89.645  1.00 190.11 ? 56  HIS A CB  1 
ATOM   22   C  CG  . HIS A 1 56  ? 126.530 137.427 89.330  1.00 190.01 ? 56  HIS A CG  1 
ATOM   23   N  ND1 . HIS A 1 56  ? 127.620 137.070 90.093  1.00 188.18 ? 56  HIS A ND1 1 
ATOM   24   C  CD2 . HIS A 1 56  ? 127.012 138.231 88.350  1.00 190.64 ? 56  HIS A CD2 1 
ATOM   25   C  CE1 . HIS A 1 56  ? 128.708 137.635 89.602  1.00 189.61 ? 56  HIS A CE1 1 
ATOM   26   N  NE2 . HIS A 1 56  ? 128.366 138.346 88.544  1.00 193.07 ? 56  HIS A NE2 1 
ATOM   27   N  N   . ARG A 1 57  ? 124.251 139.403 87.230  1.00 196.91 ? 57  ARG A N   1 
ATOM   28   C  CA  . ARG A 1 57  ? 124.484 140.796 86.874  1.00 198.59 ? 57  ARG A CA  1 
ATOM   29   C  C   . ARG A 1 57  ? 123.227 141.651 86.942  1.00 200.86 ? 57  ARG A C   1 
ATOM   30   O  O   . ARG A 1 57  ? 123.331 142.881 86.875  1.00 200.59 ? 57  ARG A O   1 
ATOM   31   C  CB  . ARG A 1 57  ? 125.083 140.885 85.468  1.00 199.23 ? 57  ARG A CB  1 
ATOM   32   C  CG  . ARG A 1 57  ? 125.897 142.142 85.209  1.00 197.47 ? 57  ARG A CG  1 
ATOM   33   C  CD  . ARG A 1 57  ? 125.886 142.504 83.734  1.00 197.16 ? 57  ARG A CD  1 
ATOM   34   N  NE  . ARG A 1 57  ? 124.684 142.024 83.063  1.00 198.48 ? 57  ARG A NE  1 
ATOM   35   C  CZ  . ARG A 1 57  ? 123.618 142.770 82.810  1.00 197.75 ? 57  ARG A CZ  1 
ATOM   36   N  NH1 . ARG A 1 57  ? 123.569 144.046 83.157  1.00 196.83 ? 57  ARG A NH1 1 
ATOM   37   N  NH2 . ARG A 1 57  ? 122.574 142.223 82.193  1.00 195.92 ? 57  ARG A NH2 1 
ATOM   38   N  N   . ASP A 1 58  ? 122.049 141.040 87.069  1.00 210.82 ? 58  ASP A N   1 
ATOM   39   C  CA  . ASP A 1 58  ? 120.817 141.823 87.145  1.00 210.61 ? 58  ASP A CA  1 
ATOM   40   C  C   . ASP A 1 58  ? 120.773 142.737 88.364  1.00 210.22 ? 58  ASP A C   1 
ATOM   41   O  O   . ASP A 1 58  ? 120.465 143.930 88.198  1.00 209.14 ? 58  ASP A O   1 
ATOM   42   C  CB  . ASP A 1 58  ? 119.607 140.883 87.093  1.00 209.01 ? 58  ASP A CB  1 
ATOM   43   C  CG  . ASP A 1 58  ? 119.541 140.091 85.803  1.00 207.89 ? 58  ASP A CG  1 
ATOM   44   O  OD1 . ASP A 1 58  ? 120.523 140.130 85.032  1.00 206.67 ? 58  ASP A OD1 1 
ATOM   45   O  OD2 . ASP A 1 58  ? 118.510 139.430 85.561  1.00 206.39 ? 58  ASP A OD2 1 
ATOM   46   N  N   . PRO A 1 59  ? 121.063 142.276 89.597  1.00 208.82 ? 59  PRO A N   1 
ATOM   47   C  CA  . PRO A 1 59  ? 121.100 143.219 90.722  1.00 207.85 ? 59  PRO A CA  1 
ATOM   48   C  C   . PRO A 1 59  ? 122.476 143.838 90.903  1.00 207.63 ? 59  PRO A C   1 
ATOM   49   O  O   . PRO A 1 59  ? 123.409 143.522 90.158  1.00 206.66 ? 59  PRO A O   1 
ATOM   50   C  CB  . PRO A 1 59  ? 120.713 142.344 91.917  1.00 205.39 ? 59  PRO A CB  1 
ATOM   51   C  CG  . PRO A 1 59  ? 121.252 140.999 91.566  1.00 204.49 ? 59  PRO A CG  1 
ATOM   52   C  CD  . PRO A 1 59  ? 121.282 140.890 90.055  1.00 206.17 ? 59  PRO A CD  1 
ATOM   53   N  N   . LEU A 1 60  ? 122.614 144.725 91.887  1.00 211.86 ? 60  LEU A N   1 
ATOM   54   C  CA  . LEU A 1 60  ? 123.888 145.359 92.178  1.00 212.31 ? 60  LEU A CA  1 
ATOM   55   C  C   . LEU A 1 60  ? 124.155 145.322 93.677  1.00 212.46 ? 60  LEU A C   1 
ATOM   56   O  O   . LEU A 1 60  ? 123.219 145.428 94.479  1.00 211.00 ? 60  LEU A O   1 
ATOM   57   C  CB  . LEU A 1 60  ? 123.905 146.812 91.682  1.00 212.17 ? 60  LEU A CB  1 
ATOM   58   C  CG  . LEU A 1 60  ? 123.840 147.004 90.166  1.00 210.78 ? 60  LEU A CG  1 
ATOM   59   C  CD1 . LEU A 1 60  ? 123.654 148.473 89.817  1.00 209.12 ? 60  LEU A CD1 1 
ATOM   60   C  CD2 . LEU A 1 60  ? 125.086 146.443 89.498  1.00 210.33 ? 60  LEU A CD2 1 
ATOM   61   N  N   . PRO A 1 61  ? 125.412 145.174 94.085  1.00 219.21 ? 61  PRO A N   1 
ATOM   62   C  CA  . PRO A 1 61  ? 125.730 145.147 95.513  1.00 219.87 ? 61  PRO A CA  1 
ATOM   63   C  C   . PRO A 1 61  ? 125.992 146.545 96.042  1.00 220.26 ? 61  PRO A C   1 
ATOM   64   O  O   . PRO A 1 61  ? 126.822 147.284 95.490  1.00 219.03 ? 61  PRO A O   1 
ATOM   65   C  CB  . PRO A 1 61  ? 126.994 144.280 95.574  1.00 218.53 ? 61  PRO A CB  1 
ATOM   66   C  CG  . PRO A 1 61  ? 127.646 144.462 94.232  1.00 217.04 ? 61  PRO A CG  1 
ATOM   67   C  CD  . PRO A 1 61  ? 126.596 144.925 93.245  1.00 217.01 ? 61  PRO A CD  1 
ATOM   68   N  N   . PRO A 1 62  ? 125.307 146.948 97.108  1.00 223.54 ? 62  PRO A N   1 
ATOM   69   C  CA  . PRO A 1 62  ? 125.548 148.268 97.691  1.00 222.83 ? 62  PRO A CA  1 
ATOM   70   C  C   . PRO A 1 62  ? 126.701 148.225 98.678  1.00 222.95 ? 62  PRO A C   1 
ATOM   71   O  O   . PRO A 1 62  ? 126.638 147.514 99.693  1.00 220.89 ? 62  PRO A O   1 
ATOM   72   C  CB  . PRO A 1 62  ? 124.222 148.591 98.393  1.00 220.83 ? 62  PRO A CB  1 
ATOM   73   C  CG  . PRO A 1 62  ? 123.592 147.255 98.679  1.00 219.94 ? 62  PRO A CG  1 
ATOM   74   C  CD  . PRO A 1 62  ? 124.257 146.203 97.824  1.00 221.24 ? 62  PRO A CD  1 
ATOM   75   N  N   . PRO A 1 63  ? 127.772 148.966 98.418  1.00 221.61 ? 63  PRO A N   1 
ATOM   76   C  CA  . PRO A 1 63  ? 128.913 148.989 99.333  1.00 220.05 ? 63  PRO A CA  1 
ATOM   77   C  C   . PRO A 1 63  ? 128.733 150.035 100.429 1.00 219.71 ? 63  PRO A C   1 
ATOM   78   O  O   . PRO A 1 63  ? 127.796 150.835 100.419 1.00 218.30 ? 63  PRO A O   1 
ATOM   79   C  CB  . PRO A 1 63  ? 130.082 149.355 98.412  1.00 219.07 ? 63  PRO A CB  1 
ATOM   80   C  CG  . PRO A 1 63  ? 129.458 150.204 97.349  1.00 219.30 ? 63  PRO A CG  1 
ATOM   81   C  CD  . PRO A 1 63  ? 128.004 149.798 97.223  1.00 219.90 ? 63  PRO A CD  1 
ATOM   82   N  N   . GLY A 1 64  ? 129.662 150.011 101.380 1.00 206.17 ? 64  GLY A N   1 
ATOM   83   C  CA  . GLY A 1 64  ? 129.634 150.949 102.480 1.00 205.22 ? 64  GLY A CA  1 
ATOM   84   C  C   . GLY A 1 64  ? 128.590 150.596 103.523 1.00 206.52 ? 64  GLY A C   1 
ATOM   85   O  O   . GLY A 1 64  ? 128.034 149.494 103.557 1.00 205.80 ? 64  GLY A O   1 
ATOM   86   N  N   . LEU A 1 65  ? 128.328 151.565 104.395 1.00 196.15 ? 65  LEU A N   1 
ATOM   87   C  CA  . LEU A 1 65  ? 127.354 151.423 105.470 1.00 196.25 ? 65  LEU A CA  1 
ATOM   88   C  C   . LEU A 1 65  ? 126.186 152.362 105.205 1.00 195.14 ? 65  LEU A C   1 
ATOM   89   O  O   . LEU A 1 65  ? 126.380 153.575 105.068 1.00 193.16 ? 65  LEU A O   1 
ATOM   90   C  CB  . LEU A 1 65  ? 127.989 151.724 106.827 1.00 195.29 ? 65  LEU A CB  1 
ATOM   91   C  CG  . LEU A 1 65  ? 129.303 151.009 107.150 1.00 194.15 ? 65  LEU A CG  1 
ATOM   92   C  CD1 . LEU A 1 65  ? 129.700 151.257 108.596 1.00 192.99 ? 65  LEU A CD1 1 
ATOM   93   C  CD2 . LEU A 1 65  ? 129.197 149.518 106.869 1.00 193.13 ? 65  LEU A CD2 1 
ATOM   94   N  N   . THR A 1 66  ? 124.982 151.804 105.135 1.00 191.71 ? 66  THR A N   1 
ATOM   95   C  CA  . THR A 1 66  ? 123.804 152.617 104.892 1.00 191.22 ? 66  THR A CA  1 
ATOM   96   C  C   . THR A 1 66  ? 123.511 153.499 106.105 1.00 191.79 ? 66  THR A C   1 
ATOM   97   O  O   . THR A 1 66  ? 123.783 153.111 107.244 1.00 192.16 ? 66  THR A O   1 
ATOM   98   C  CB  . THR A 1 66  ? 122.594 151.737 104.590 1.00 189.31 ? 66  THR A CB  1 
ATOM   99   O  OG1 . THR A 1 66  ? 122.065 151.214 105.813 1.00 190.20 ? 66  THR A OG1 1 
ATOM   100  C  CG2 . THR A 1 66  ? 122.991 150.582 103.686 1.00 187.81 ? 66  THR A CG2 1 
ATOM   101  N  N   . PRO A 1 67  ? 122.971 154.700 105.883 1.00 188.64 ? 67  PRO A N   1 
ATOM   102  C  CA  . PRO A 1 67  ? 122.637 155.569 107.023 1.00 188.07 ? 67  PRO A CA  1 
ATOM   103  C  C   . PRO A 1 67  ? 121.647 154.946 107.990 1.00 188.02 ? 67  PRO A C   1 
ATOM   104  O  O   . PRO A 1 67  ? 121.747 155.181 109.200 1.00 187.25 ? 67  PRO A O   1 
ATOM   105  C  CB  . PRO A 1 67  ? 122.056 156.821 106.350 1.00 185.77 ? 67  PRO A CB  1 
ATOM   106  C  CG  . PRO A 1 67  ? 122.608 156.801 104.965 1.00 186.65 ? 67  PRO A CG  1 
ATOM   107  C  CD  . PRO A 1 67  ? 122.715 155.356 104.591 1.00 187.31 ? 67  PRO A CD  1 
ATOM   108  N  N   . GLU A 1 68  ? 120.692 154.156 107.495 1.00 185.68 ? 68  GLU A N   1 
ATOM   109  C  CA  . GLU A 1 68  ? 119.725 153.531 108.389 1.00 185.36 ? 68  GLU A CA  1 
ATOM   110  C  C   . GLU A 1 68  ? 120.366 152.439 109.235 1.00 186.26 ? 68  GLU A C   1 
ATOM   111  O  O   . GLU A 1 68  ? 119.928 152.197 110.366 1.00 187.74 ? 68  GLU A O   1 
ATOM   112  C  CB  . GLU A 1 68  ? 118.547 152.973 107.589 1.00 185.35 ? 68  GLU A CB  1 
ATOM   113  C  CG  . GLU A 1 68  ? 118.851 151.701 106.816 1.00 185.95 ? 68  GLU A CG  1 
ATOM   114  C  CD  . GLU A 1 68  ? 118.443 150.452 107.572 1.00 187.15 ? 68  GLU A CD  1 
ATOM   115  O  OE1 . GLU A 1 68  ? 117.308 150.414 108.091 1.00 187.00 ? 68  GLU A OE1 1 
ATOM   116  O  OE2 . GLU A 1 68  ? 119.260 149.512 107.652 1.00 186.36 ? 68  GLU A OE2 1 
ATOM   117  N  N   . ARG A 1 69  ? 121.395 151.767 108.712 1.00 181.80 ? 69  ARG A N   1 
ATOM   118  C  CA  . ARG A 1 69  ? 122.066 150.740 109.500 1.00 181.19 ? 69  ARG A CA  1 
ATOM   119  C  C   . ARG A 1 69  ? 122.835 151.347 110.664 1.00 181.58 ? 69  ARG A C   1 
ATOM   120  O  O   . ARG A 1 69  ? 122.930 150.729 111.729 1.00 183.72 ? 69  ARG A O   1 
ATOM   121  C  CB  . ARG A 1 69  ? 122.997 149.914 108.616 1.00 181.68 ? 69  ARG A CB  1 
ATOM   122  C  CG  . ARG A 1 69  ? 122.401 148.585 108.181 1.00 181.65 ? 69  ARG A CG  1 
ATOM   123  C  CD  . ARG A 1 69  ? 123.483 147.596 107.785 1.00 183.07 ? 69  ARG A CD  1 
ATOM   124  N  NE  . ARG A 1 69  ? 124.003 147.861 106.449 1.00 185.38 ? 69  ARG A NE  1 
ATOM   125  C  CZ  . ARG A 1 69  ? 125.152 148.475 106.203 1.00 185.72 ? 69  ARG A CZ  1 
ATOM   126  N  NH1 . ARG A 1 69  ? 125.929 148.905 107.183 1.00 182.69 ? 69  ARG A NH1 1 
ATOM   127  N  NH2 . ARG A 1 69  ? 125.530 148.663 104.942 1.00 183.99 ? 69  ARG A NH2 1 
ATOM   128  N  N   . LEU A 1 70  ? 123.385 152.550 110.486 1.00 168.30 ? 70  LEU A N   1 
ATOM   129  C  CA  . LEU A 1 70  ? 123.996 153.248 111.612 1.00 170.31 ? 70  LEU A CA  1 
ATOM   130  C  C   . LEU A 1 70  ? 122.966 153.531 112.697 1.00 169.98 ? 70  LEU A C   1 
ATOM   131  O  O   . LEU A 1 70  ? 123.245 153.365 113.892 1.00 170.90 ? 70  LEU A O   1 
ATOM   132  C  CB  . LEU A 1 70  ? 124.646 154.546 111.135 1.00 170.36 ? 70  LEU A CB  1 
ATOM   133  C  CG  . LEU A 1 70  ? 126.142 154.494 110.823 1.00 172.01 ? 70  LEU A CG  1 
ATOM   134  C  CD1 . LEU A 1 70  ? 126.937 154.143 112.071 1.00 168.78 ? 70  LEU A CD1 1 
ATOM   135  C  CD2 . LEU A 1 70  ? 126.432 153.507 109.703 1.00 172.05 ? 70  LEU A CD2 1 
ATOM   136  N  N   . HIS A 1 71  ? 121.766 153.954 112.297 1.00 162.20 ? 71  HIS A N   1 
ATOM   137  C  CA  . HIS A 1 71  ? 120.704 154.180 113.269 1.00 162.21 ? 71  HIS A CA  1 
ATOM   138  C  C   . HIS A 1 71  ? 120.318 152.888 113.975 1.00 162.19 ? 71  HIS A C   1 
ATOM   139  O  O   . HIS A 1 71  ? 120.099 152.879 115.191 1.00 166.45 ? 71  HIS A O   1 
ATOM   140  C  CB  . HIS A 1 71  ? 119.489 154.799 112.584 1.00 160.41 ? 71  HIS A CB  1 
ATOM   141  C  CG  . HIS A 1 71  ? 118.510 155.410 113.535 1.00 161.81 ? 71  HIS A CG  1 
ATOM   142  N  ND1 . HIS A 1 71  ? 118.870 156.368 114.458 1.00 162.63 ? 71  HIS A ND1 1 
ATOM   143  C  CD2 . HIS A 1 71  ? 117.184 155.201 113.707 1.00 161.02 ? 71  HIS A CD2 1 
ATOM   144  C  CE1 . HIS A 1 71  ? 117.808 156.722 115.159 1.00 162.81 ? 71  HIS A CE1 1 
ATOM   145  N  NE2 . HIS A 1 71  ? 116.772 156.029 114.722 1.00 162.75 ? 71  HIS A NE2 1 
ATOM   146  N  N   . ALA A 1 72  ? 120.226 151.786 113.228 1.00 151.35 ? 72  ALA A N   1 
ATOM   147  C  CA  . ALA A 1 72  ? 119.896 150.505 113.846 1.00 149.91 ? 72  ALA A CA  1 
ATOM   148  C  C   . ALA A 1 72  ? 120.967 150.085 114.844 1.00 153.10 ? 72  ALA A C   1 
ATOM   149  O  O   . ALA A 1 72  ? 120.654 149.575 115.927 1.00 158.15 ? 72  ALA A O   1 
ATOM   150  C  CB  . ALA A 1 72  ? 119.713 149.435 112.772 1.00 149.08 ? 72  ALA A CB  1 
ATOM   151  N  N   . ARG A 1 73  ? 122.237 150.294 114.497 1.00 148.16 ? 73  ARG A N   1 
ATOM   152  C  CA  . ARG A 1 73  ? 123.318 149.987 115.426 1.00 147.52 ? 73  ARG A CA  1 
ATOM   153  C  C   . ARG A 1 73  ? 123.223 150.843 116.681 1.00 149.36 ? 73  ARG A C   1 
ATOM   154  O  O   . ARG A 1 73  ? 123.453 150.356 117.792 1.00 151.28 ? 73  ARG A O   1 
ATOM   155  C  CB  . ARG A 1 73  ? 124.669 150.188 114.744 1.00 150.31 ? 73  ARG A CB  1 
ATOM   156  C  CG  . ARG A 1 73  ? 125.094 149.034 113.860 1.00 151.93 ? 73  ARG A CG  1 
ATOM   157  C  CD  . ARG A 1 73  ? 126.573 148.732 114.021 1.00 152.30 ? 73  ARG A CD  1 
ATOM   158  N  NE  . ARG A 1 73  ? 127.406 149.658 113.264 1.00 154.87 ? 73  ARG A NE  1 
ATOM   159  C  CZ  . ARG A 1 73  ? 128.047 150.691 113.793 1.00 153.95 ? 73  ARG A CZ  1 
ATOM   160  N  NH1 . ARG A 1 73  ? 127.972 150.962 115.085 1.00 151.58 ? 73  ARG A NH1 1 
ATOM   161  N  NH2 . ARG A 1 73  ? 128.783 151.470 113.006 1.00 152.02 ? 73  ARG A NH2 1 
ATOM   162  N  N   . ARG A 1 74  ? 122.896 152.127 116.522 1.00 151.05 ? 74  ARG A N   1 
ATOM   163  C  CA  . ARG A 1 74  ? 122.756 152.995 117.687 1.00 149.46 ? 74  ARG A CA  1 
ATOM   164  C  C   . ARG A 1 74  ? 121.614 152.536 118.587 1.00 149.63 ? 74  ARG A C   1 
ATOM   165  O  O   . ARG A 1 74  ? 121.752 152.514 119.818 1.00 153.03 ? 74  ARG A O   1 
ATOM   166  C  CB  . ARG A 1 74  ? 122.545 154.440 117.241 1.00 149.08 ? 74  ARG A CB  1 
ATOM   167  C  CG  . ARG A 1 74  ? 123.834 155.226 117.094 1.00 151.74 ? 74  ARG A CG  1 
ATOM   168  C  CD  . ARG A 1 74  ? 123.576 156.622 116.558 1.00 152.90 ? 74  ARG A CD  1 
ATOM   169  N  NE  . ARG A 1 74  ? 124.525 156.980 115.511 1.00 155.76 ? 74  ARG A NE  1 
ATOM   170  C  CZ  . ARG A 1 74  ? 124.253 156.960 114.213 1.00 156.59 ? 74  ARG A CZ  1 
ATOM   171  N  NH1 . ARG A 1 74  ? 123.060 156.607 113.762 1.00 155.03 ? 74  ARG A NH1 1 
ATOM   172  N  NH2 . ARG A 1 74  ? 125.201 157.302 113.346 1.00 154.00 ? 74  ARG A NH2 1 
ATOM   173  N  N   . GLN A 1 75  ? 120.477 152.168 117.992 1.00 142.83 ? 75  GLN A N   1 
ATOM   174  C  CA  . GLN A 1 75  ? 119.363 151.666 118.791 1.00 143.01 ? 75  GLN A CA  1 
ATOM   175  C  C   . GLN A 1 75  ? 119.738 150.385 119.520 1.00 142.46 ? 75  GLN A C   1 
ATOM   176  O  O   . GLN A 1 75  ? 119.393 150.208 120.694 1.00 149.02 ? 75  GLN A O   1 
ATOM   177  C  CB  . GLN A 1 75  ? 118.127 151.438 117.924 1.00 143.63 ? 75  GLN A CB  1 
ATOM   178  C  CG  . GLN A 1 75  ? 117.726 152.613 117.062 1.00 145.37 ? 75  GLN A CG  1 
ATOM   179  C  CD  . GLN A 1 75  ? 116.324 152.467 116.511 1.00 147.35 ? 75  GLN A CD  1 
ATOM   180  O  OE1 . GLN A 1 75  ? 115.849 151.356 116.278 1.00 149.12 ? 75  GLN A OE1 1 
ATOM   181  N  NE2 . GLN A 1 75  ? 115.649 153.591 116.306 1.00 145.02 ? 75  GLN A NE2 1 
ATOM   182  N  N   . LEU A 1 76  ? 120.438 149.474 118.842 1.00 129.82 ? 76  LEU A N   1 
ATOM   183  C  CA  . LEU A 1 76  ? 120.858 148.244 119.503 1.00 128.48 ? 76  LEU A CA  1 
ATOM   184  C  C   . LEU A 1 76  ? 121.828 148.523 120.643 1.00 129.85 ? 76  LEU A C   1 
ATOM   185  O  O   . LEU A 1 76  ? 121.736 147.887 121.697 1.00 133.94 ? 76  LEU A O   1 
ATOM   186  C  CB  . LEU A 1 76  ? 121.480 147.285 118.492 1.00 132.18 ? 76  LEU A CB  1 
ATOM   187  C  CG  . LEU A 1 76  ? 120.486 146.438 117.699 1.00 131.28 ? 76  LEU A CG  1 
ATOM   188  C  CD1 . LEU A 1 76  ? 121.198 145.640 116.625 1.00 130.23 ? 76  LEU A CD1 1 
ATOM   189  C  CD2 . LEU A 1 76  ? 119.715 145.520 118.623 1.00 132.51 ? 76  LEU A CD2 1 
ATOM   190  N  N   . TYR A 1 77  ? 122.754 149.467 120.458 1.00 133.85 ? 77  TYR A N   1 
ATOM   191  C  CA  . TYR A 1 77  ? 123.661 149.839 121.540 1.00 133.74 ? 77  TYR A CA  1 
ATOM   192  C  C   . TYR A 1 77  ? 122.895 150.379 122.740 1.00 136.42 ? 77  TYR A C   1 
ATOM   193  O  O   . TYR A 1 77  ? 123.155 149.985 123.885 1.00 138.00 ? 77  TYR A O   1 
ATOM   194  C  CB  . TYR A 1 77  ? 124.662 150.884 121.051 1.00 137.80 ? 77  TYR A CB  1 
ATOM   195  C  CG  . TYR A 1 77  ? 125.774 150.336 120.193 1.00 140.47 ? 77  TYR A CG  1 
ATOM   196  C  CD1 . TYR A 1 77  ? 126.221 149.034 120.349 1.00 138.83 ? 77  TYR A CD1 1 
ATOM   197  C  CD2 . TYR A 1 77  ? 126.379 151.125 119.226 1.00 139.13 ? 77  TYR A CD2 1 
ATOM   198  C  CE1 . TYR A 1 77  ? 127.238 148.532 119.566 1.00 138.94 ? 77  TYR A CE1 1 
ATOM   199  C  CE2 . TYR A 1 77  ? 127.396 150.631 118.439 1.00 139.35 ? 77  TYR A CE2 1 
ATOM   200  C  CZ  . TYR A 1 77  ? 127.822 149.334 118.613 1.00 142.33 ? 77  TYR A CZ  1 
ATOM   201  O  OH  . TYR A 1 77  ? 128.837 148.837 117.830 1.00 145.53 ? 77  TYR A OH  1 
ATOM   202  N  N   . ALA A 1 78  ? 121.948 151.288 122.496 1.00 125.85 ? 78  ALA A N   1 
ATOM   203  C  CA  . ALA A 1 78  ? 121.186 151.873 123.595 1.00 124.21 ? 78  ALA A CA  1 
ATOM   204  C  C   . ALA A 1 78  ? 120.374 150.810 124.324 1.00 127.54 ? 78  ALA A C   1 
ATOM   205  O  O   . ALA A 1 78  ? 120.332 150.779 125.560 1.00 135.30 ? 78  ALA A O   1 
ATOM   206  C  CB  . ALA A 1 78  ? 120.277 152.982 123.069 1.00 125.86 ? 78  ALA A CB  1 
ATOM   207  N  N   . ALA A 1 79  ? 119.725 149.924 123.568 1.00 120.77 ? 79  ALA A N   1 
ATOM   208  C  CA  . ALA A 1 79  ? 118.920 148.877 124.183 1.00 119.45 ? 79  ALA A CA  1 
ATOM   209  C  C   . ALA A 1 79  ? 119.784 147.919 124.990 1.00 121.39 ? 79  ALA A C   1 
ATOM   210  O  O   . ALA A 1 79  ? 119.400 147.506 126.090 1.00 126.82 ? 79  ALA A O   1 
ATOM   211  C  CB  . ALA A 1 79  ? 118.134 148.125 123.113 1.00 120.20 ? 79  ALA A CB  1 
ATOM   212  N  N   . CYS A 1 80  ? 120.957 147.554 124.464 1.00 126.25 ? 80  CYS A N   1 
ATOM   213  C  CA  . CYS A 1 80  ? 121.857 146.683 125.210 1.00 122.58 ? 80  CYS A CA  1 
ATOM   214  C  C   . CYS A 1 80  ? 122.311 147.339 126.503 1.00 124.45 ? 80  CYS A C   1 
ATOM   215  O  O   . CYS A 1 80  ? 122.343 146.692 127.554 1.00 132.32 ? 80  CYS A O   1 
ATOM   216  C  CB  . CYS A 1 80  ? 123.065 146.310 124.354 1.00 128.58 ? 80  CYS A CB  1 
ATOM   217  S  SG  . CYS A 1 80  ? 122.889 144.777 123.432 1.00 134.66 ? 80  CYS A SG  1 
ATOM   218  N  N   . ALA A 1 81  ? 122.662 148.625 126.451 1.00 116.49 ? 81  ALA A N   1 
ATOM   219  C  CA  . ALA A 1 81  ? 123.098 149.312 127.662 1.00 117.27 ? 81  ALA A CA  1 
ATOM   220  C  C   . ALA A 1 81  ? 121.986 149.350 128.702 1.00 120.03 ? 81  ALA A C   1 
ATOM   221  O  O   . ALA A 1 81  ? 122.208 149.041 129.882 1.00 122.19 ? 81  ALA A O   1 
ATOM   222  C  CB  . ALA A 1 81  ? 123.567 150.726 127.323 1.00 118.87 ? 81  ALA A CB  1 
ATOM   223  N  N   . VAL A 1 82  ? 120.773 149.712 128.277 1.00 123.25 ? 82  VAL A N   1 
ATOM   224  C  CA  . VAL A 1 82  ? 119.656 149.803 129.212 1.00 121.17 ? 82  VAL A CA  1 
ATOM   225  C  C   . VAL A 1 82  ? 119.341 148.445 129.819 1.00 123.08 ? 82  VAL A C   1 
ATOM   226  O  O   . VAL A 1 82  ? 119.162 148.326 131.040 1.00 127.06 ? 82  VAL A O   1 
ATOM   227  C  CB  . VAL A 1 82  ? 118.425 150.403 128.509 1.00 118.57 ? 82  VAL A CB  1 
ATOM   228  C  CG1 . VAL A 1 82  ? 117.197 150.264 129.385 1.00 121.50 ? 82  VAL A CG1 1 
ATOM   229  C  CG2 . VAL A 1 82  ? 118.673 151.858 128.171 1.00 119.80 ? 82  VAL A CG2 1 
ATOM   230  N  N   . CYS A 1 83  ? 119.280 147.400 128.994 1.00 125.32 ? 83  CYS A N   1 
ATOM   231  C  CA  . CYS A 1 83  ? 118.958 146.076 129.507 1.00 123.09 ? 83  CYS A CA  1 
ATOM   232  C  C   . CYS A 1 83  ? 120.059 145.539 130.412 1.00 124.49 ? 83  CYS A C   1 
ATOM   233  O  O   . CYS A 1 83  ? 119.768 144.853 131.394 1.00 132.12 ? 83  CYS A O   1 
ATOM   234  C  CB  . CYS A 1 83  ? 118.689 145.116 128.352 1.00 125.97 ? 83  CYS A CB  1 
ATOM   235  S  SG  . CYS A 1 83  ? 117.149 145.431 127.468 1.00 138.66 ? 83  CYS A SG  1 
ATOM   236  N  N   . PHE A 1 84  ? 121.326 145.841 130.113 1.00 122.86 ? 84  PHE A N   1 
ATOM   237  C  CA  . PHE A 1 84  ? 122.406 145.398 130.987 1.00 123.87 ? 84  PHE A CA  1 
ATOM   238  C  C   . PHE A 1 84  ? 122.345 146.093 132.340 1.00 122.42 ? 84  PHE A C   1 
ATOM   239  O  O   . PHE A 1 84  ? 122.564 145.462 133.380 1.00 122.79 ? 84  PHE A O   1 
ATOM   240  C  CB  . PHE A 1 84  ? 123.759 145.641 130.323 1.00 125.05 ? 84  PHE A CB  1 
ATOM   241  C  CG  . PHE A 1 84  ? 124.918 145.081 131.094 1.00 126.63 ? 84  PHE A CG  1 
ATOM   242  C  CD1 . PHE A 1 84  ? 125.315 143.768 130.914 1.00 127.89 ? 84  PHE A CD1 1 
ATOM   243  C  CD2 . PHE A 1 84  ? 125.609 145.865 132.001 1.00 125.67 ? 84  PHE A CD2 1 
ATOM   244  C  CE1 . PHE A 1 84  ? 126.376 143.249 131.623 1.00 128.82 ? 84  PHE A CE1 1 
ATOM   245  C  CE2 . PHE A 1 84  ? 126.670 145.351 132.714 1.00 127.21 ? 84  PHE A CE2 1 
ATOM   246  C  CZ  . PHE A 1 84  ? 127.055 144.042 132.524 1.00 127.35 ? 84  PHE A CZ  1 
ATOM   247  N  N   . VAL A 1 85  ? 122.059 147.397 132.348 1.00 117.13 ? 85  VAL A N   1 
ATOM   248  C  CA  . VAL A 1 85  ? 121.923 148.104 133.619 1.00 118.70 ? 85  VAL A CA  1 
ATOM   249  C  C   . VAL A 1 85  ? 120.764 147.529 134.422 1.00 122.68 ? 85  VAL A C   1 
ATOM   250  O  O   . VAL A 1 85  ? 120.878 147.296 135.635 1.00 123.57 ? 85  VAL A O   1 
ATOM   251  C  CB  . VAL A 1 85  ? 121.752 149.614 133.374 1.00 118.99 ? 85  VAL A CB  1 
ATOM   252  C  CG1 . VAL A 1 85  ? 121.320 150.312 134.648 1.00 117.74 ? 85  VAL A CG1 1 
ATOM   253  C  CG2 . VAL A 1 85  ? 123.044 150.210 132.855 1.00 120.29 ? 85  VAL A CG2 1 
ATOM   254  N  N   . PHE A 1 86  ? 119.635 147.281 133.755 1.00 122.59 ? 86  PHE A N   1 
ATOM   255  C  CA  . PHE A 1 86  ? 118.484 146.687 134.426 1.00 118.32 ? 86  PHE A CA  1 
ATOM   256  C  C   . PHE A 1 86  ? 118.823 145.315 134.997 1.00 120.47 ? 86  PHE A C   1 
ATOM   257  O  O   . PHE A 1 86  ? 118.463 145.001 136.138 1.00 124.79 ? 86  PHE A O   1 
ATOM   258  C  CB  . PHE A 1 86  ? 117.319 146.595 133.441 1.00 120.31 ? 86  PHE A CB  1 
ATOM   259  C  CG  . PHE A 1 86  ? 115.978 146.416 134.087 1.00 125.16 ? 86  PHE A CG  1 
ATOM   260  C  CD1 . PHE A 1 86  ? 115.822 146.545 135.455 1.00 128.92 ? 86  PHE A CD1 1 
ATOM   261  C  CD2 . PHE A 1 86  ? 114.868 146.124 133.318 1.00 123.98 ? 86  PHE A CD2 1 
ATOM   262  C  CE1 . PHE A 1 86  ? 114.585 146.376 136.040 1.00 127.21 ? 86  PHE A CE1 1 
ATOM   263  C  CE2 . PHE A 1 86  ? 113.631 145.957 133.898 1.00 127.27 ? 86  PHE A CE2 1 
ATOM   264  C  CZ  . PHE A 1 86  ? 113.490 146.083 135.260 1.00 127.42 ? 86  PHE A CZ  1 
ATOM   265  N  N   . MET A 1 87  ? 119.528 144.491 134.220 1.00 121.22 ? 87  MET A N   1 
ATOM   266  C  CA  . MET A 1 87  ? 119.896 143.158 134.680 1.00 118.25 ? 87  MET A CA  1 
ATOM   267  C  C   . MET A 1 87  ? 120.819 143.221 135.887 1.00 124.10 ? 87  MET A C   1 
ATOM   268  O  O   . MET A 1 87  ? 120.645 142.463 136.846 1.00 127.77 ? 87  MET A O   1 
ATOM   269  C  CB  . MET A 1 87  ? 120.565 142.383 133.548 1.00 119.36 ? 87  MET A CB  1 
ATOM   270  C  CG  . MET A 1 87  ? 121.193 141.078 133.989 1.00 120.55 ? 87  MET A CG  1 
ATOM   271  S  SD  . MET A 1 87  ? 122.127 140.285 132.673 1.00 135.21 ? 87  MET A SD  1 
ATOM   272  C  CE  . MET A 1 87  ? 123.690 141.143 132.810 1.00 129.08 ? 87  MET A CE  1 
ATOM   273  N  N   . ALA A 1 88  ? 121.815 144.108 135.856 1.00 124.82 ? 88  ALA A N   1 
ATOM   274  C  CA  . ALA A 1 88  ? 122.726 144.223 136.989 1.00 121.20 ? 88  ALA A CA  1 
ATOM   275  C  C   . ALA A 1 88  ? 121.992 144.676 138.243 1.00 124.51 ? 88  ALA A C   1 
ATOM   276  O  O   . ALA A 1 88  ? 122.190 144.111 139.328 1.00 130.23 ? 88  ALA A O   1 
ATOM   277  C  CB  . ALA A 1 88  ? 123.863 145.185 136.655 1.00 121.72 ? 88  ALA A CB  1 
ATOM   278  N  N   . GLY A 1 89  ? 121.128 145.685 138.111 1.00 115.64 ? 89  GLY A N   1 
ATOM   279  C  CA  . GLY A 1 89  ? 120.365 146.137 139.260 1.00 115.23 ? 89  GLY A CA  1 
ATOM   280  C  C   . GLY A 1 89  ? 119.475 145.053 139.831 1.00 116.44 ? 89  GLY A C   1 
ATOM   281  O  O   . GLY A 1 89  ? 119.387 144.884 141.050 1.00 117.31 ? 89  GLY A O   1 
ATOM   282  N  N   . GLU A 1 90  ? 118.814 144.291 138.958 1.00 124.19 ? 90  GLU A N   1 
ATOM   283  C  CA  . GLU A 1 90  ? 117.914 143.251 139.441 1.00 121.59 ? 90  GLU A CA  1 
ATOM   284  C  C   . GLU A 1 90  ? 118.683 142.097 140.069 1.00 122.07 ? 90  GLU A C   1 
ATOM   285  O  O   . GLU A 1 90  ? 118.224 141.508 141.051 1.00 126.49 ? 90  GLU A O   1 
ATOM   286  C  CB  . GLU A 1 90  ? 117.019 142.757 138.309 1.00 122.33 ? 90  GLU A CB  1 
ATOM   287  C  CG  . GLU A 1 90  ? 115.547 142.862 138.645 1.00 124.35 ? 90  GLU A CG  1 
ATOM   288  C  CD  . GLU A 1 90  ? 114.663 142.190 137.626 1.00 130.29 ? 90  GLU A CD  1 
ATOM   289  O  OE1 . GLU A 1 90  ? 115.165 141.859 136.533 1.00 128.53 ? 90  GLU A OE1 1 
ATOM   290  O  OE2 . GLU A 1 90  ? 113.462 142.003 137.914 1.00 131.41 ? 90  GLU A OE2 1 
ATOM   291  N  N   . VAL A 1 91  ? 119.853 141.756 139.523 1.00 123.04 ? 91  VAL A N   1 
ATOM   292  C  CA  . VAL A 1 91  ? 120.680 140.729 140.148 1.00 124.60 ? 91  VAL A CA  1 
ATOM   293  C  C   . VAL A 1 91  ? 121.107 141.164 141.539 1.00 123.77 ? 91  VAL A C   1 
ATOM   294  O  O   . VAL A 1 91  ? 121.024 140.383 142.495 1.00 127.53 ? 91  VAL A O   1 
ATOM   295  C  CB  . VAL A 1 91  ? 121.903 140.401 139.270 1.00 124.56 ? 91  VAL A CB  1 
ATOM   296  C  CG1 . VAL A 1 91  ? 122.925 139.617 140.065 1.00 122.62 ? 91  VAL A CG1 1 
ATOM   297  C  CG2 . VAL A 1 91  ? 121.482 139.610 138.053 1.00 126.41 ? 91  VAL A CG2 1 
ATOM   298  N  N   . VAL A 1 92  ? 121.552 142.411 141.684 1.00 110.51 ? 92  VAL A N   1 
ATOM   299  C  CA  . VAL A 1 92  ? 121.955 142.906 142.998 1.00 108.28 ? 92  VAL A CA  1 
ATOM   300  C  C   . VAL A 1 92  ? 120.784 142.857 143.972 1.00 115.24 ? 92  VAL A C   1 
ATOM   301  O  O   . VAL A 1 92  ? 120.913 142.374 145.103 1.00 121.41 ? 92  VAL A O   1 
ATOM   302  C  CB  . VAL A 1 92  ? 122.533 144.328 142.882 1.00 113.31 ? 92  VAL A CB  1 
ATOM   303  C  CG1 . VAL A 1 92  ? 122.645 144.968 144.253 1.00 112.11 ? 92  VAL A CG1 1 
ATOM   304  C  CG2 . VAL A 1 92  ? 123.884 144.292 142.196 1.00 117.60 ? 92  VAL A CG2 1 
ATOM   305  N  N   . GLY A 1 93  ? 119.618 143.337 143.536 1.00 121.17 ? 93  GLY A N   1 
ATOM   306  C  CA  . GLY A 1 93  ? 118.461 143.350 144.417 1.00 120.26 ? 93  GLY A CA  1 
ATOM   307  C  C   . GLY A 1 93  ? 118.015 141.963 144.832 1.00 120.13 ? 93  GLY A C   1 
ATOM   308  O  O   . GLY A 1 93  ? 117.729 141.716 146.006 1.00 124.36 ? 93  GLY A O   1 
ATOM   309  N  N   . GLY A 1 94  ? 117.954 141.035 143.878 1.00 116.78 ? 94  GLY A N   1 
ATOM   310  C  CA  . GLY A 1 94  ? 117.540 139.683 144.204 1.00 112.02 ? 94  GLY A CA  1 
ATOM   311  C  C   . GLY A 1 94  ? 118.530 138.967 145.099 1.00 119.19 ? 94  GLY A C   1 
ATOM   312  O  O   . GLY A 1 94  ? 118.135 138.224 146.002 1.00 127.87 ? 94  GLY A O   1 
ATOM   313  N  N   . TYR A 1 95  ? 119.829 139.169 144.862 1.00 126.94 ? 95  TYR A N   1 
ATOM   314  C  CA  . TYR A 1 95  ? 120.828 138.585 145.749 1.00 123.14 ? 95  TYR A CA  1 
ATOM   315  C  C   . TYR A 1 95  ? 120.694 139.141 147.157 1.00 122.11 ? 95  TYR A C   1 
ATOM   316  O  O   . TYR A 1 95  ? 120.822 138.403 148.139 1.00 120.79 ? 95  TYR A O   1 
ATOM   317  C  CB  . TYR A 1 95  ? 122.233 138.835 145.207 1.00 125.45 ? 95  TYR A CB  1 
ATOM   318  C  CG  . TYR A 1 95  ? 123.323 138.284 146.097 1.00 130.95 ? 95  TYR A CG  1 
ATOM   319  C  CD1 . TYR A 1 95  ? 124.005 139.107 146.983 1.00 130.51 ? 95  TYR A CD1 1 
ATOM   320  C  CD2 . TYR A 1 95  ? 123.664 136.940 146.059 1.00 127.66 ? 95  TYR A CD2 1 
ATOM   321  C  CE1 . TYR A 1 95  ? 124.996 138.608 147.801 1.00 131.59 ? 95  TYR A CE1 1 
ATOM   322  C  CE2 . TYR A 1 95  ? 124.655 136.431 146.874 1.00 128.35 ? 95  TYR A CE2 1 
ATOM   323  C  CZ  . TYR A 1 95  ? 125.318 137.270 147.743 1.00 134.23 ? 95  TYR A CZ  1 
ATOM   324  O  OH  . TYR A 1 95  ? 126.306 136.769 148.556 1.00 133.63 ? 95  TYR A OH  1 
ATOM   325  N  N   . LEU A 1 96  ? 120.439 140.445 147.277 1.00 119.07 ? 96  LEU A N   1 
ATOM   326  C  CA  . LEU A 1 96  ? 120.202 141.018 148.596 1.00 121.33 ? 96  LEU A CA  1 
ATOM   327  C  C   . LEU A 1 96  ? 118.946 140.444 149.236 1.00 122.87 ? 96  LEU A C   1 
ATOM   328  O  O   . LEU A 1 96  ? 118.881 140.311 150.463 1.00 125.72 ? 96  LEU A O   1 
ATOM   329  C  CB  . LEU A 1 96  ? 120.100 142.539 148.498 1.00 122.67 ? 96  LEU A CB  1 
ATOM   330  C  CG  . LEU A 1 96  ? 121.322 143.332 148.956 1.00 121.55 ? 96  LEU A CG  1 
ATOM   331  C  CD1 . LEU A 1 96  ? 122.590 142.741 148.373 1.00 119.98 ? 96  LEU A CD1 1 
ATOM   332  C  CD2 . LEU A 1 96  ? 121.180 144.791 148.567 1.00 121.08 ? 96  LEU A CD2 1 
ATOM   333  N  N   . ALA A 1 97  ? 117.944 140.102 148.430 1.00 125.14 ? 97  ALA A N   1 
ATOM   334  C  CA  . ALA A 1 97  ? 116.684 139.586 148.946 1.00 123.08 ? 97  ALA A CA  1 
ATOM   335  C  C   . ALA A 1 97  ? 116.625 138.066 149.012 1.00 121.13 ? 97  ALA A C   1 
ATOM   336  O  O   . ALA A 1 97  ? 115.633 137.529 149.515 1.00 121.60 ? 97  ALA A O   1 
ATOM   337  C  CB  . ALA A 1 97  ? 115.522 140.093 148.091 1.00 122.11 ? 97  ALA A CB  1 
ATOM   338  N  N   . HIS A 1 98  ? 117.649 137.366 148.523 1.00 124.04 ? 98  HIS A N   1 
ATOM   339  C  CA  . HIS A 1 98  ? 117.663 135.901 148.485 1.00 123.64 ? 98  HIS A CA  1 
ATOM   340  C  C   . HIS A 1 98  ? 116.446 135.352 147.745 1.00 127.37 ? 98  HIS A C   1 
ATOM   341  O  O   . HIS A 1 98  ? 115.894 134.312 148.108 1.00 131.20 ? 98  HIS A O   1 
ATOM   342  C  CB  . HIS A 1 98  ? 117.750 135.304 149.891 1.00 124.52 ? 98  HIS A CB  1 
ATOM   343  C  CG  . HIS A 1 98  ? 118.799 135.931 150.753 1.00 130.52 ? 98  HIS A CG  1 
ATOM   344  N  ND1 . HIS A 1 98  ? 118.534 136.409 152.018 1.00 131.36 ? 98  HIS A ND1 1 
ATOM   345  C  CD2 . HIS A 1 98  ? 120.116 136.155 150.535 1.00 131.52 ? 98  HIS A CD2 1 
ATOM   346  C  CE1 . HIS A 1 98  ? 119.642 136.903 152.541 1.00 130.41 ? 98  HIS A CE1 1 
ATOM   347  N  NE2 . HIS A 1 98  ? 120.617 136.761 151.662 1.00 134.89 ? 98  HIS A NE2 1 
ATOM   348  N  N   . SER A 1 99  ? 116.030 136.048 146.695 1.00 121.84 ? 99  SER A N   1 
ATOM   349  C  CA  . SER A 1 99  ? 114.839 135.688 145.942 1.00 114.60 ? 99  SER A CA  1 
ATOM   350  C  C   . SER A 1 99  ? 115.216 134.990 144.643 1.00 117.50 ? 99  SER A C   1 
ATOM   351  O  O   . SER A 1 99  ? 116.242 135.290 144.029 1.00 123.16 ? 99  SER A O   1 
ATOM   352  C  CB  . SER A 1 99  ? 113.995 136.924 145.637 1.00 113.95 ? 99  SER A CB  1 
ATOM   353  O  OG  . SER A 1 99  ? 112.698 136.555 145.215 1.00 121.31 ? 99  SER A OG  1 
ATOM   354  N  N   . LEU A 1 100 ? 114.370 134.050 144.229 1.00 110.16 ? 100 LEU A N   1 
ATOM   355  C  CA  . LEU A 1 100 ? 114.583 133.319 142.989 1.00 112.33 ? 100 LEU A CA  1 
ATOM   356  C  C   . LEU A 1 100 ? 113.712 133.813 141.845 1.00 115.62 ? 100 LEU A C   1 
ATOM   357  O  O   . LEU A 1 100 ? 114.076 133.622 140.682 1.00 121.40 ? 100 LEU A O   1 
ATOM   358  C  CB  . LEU A 1 100 ? 114.331 131.824 143.201 1.00 112.46 ? 100 LEU A CB  1 
ATOM   359  C  CG  . LEU A 1 100 ? 115.523 131.004 143.690 1.00 113.60 ? 100 LEU A CG  1 
ATOM   360  C  CD1 . LEU A 1 100 ? 115.218 129.524 143.590 1.00 116.42 ? 100 LEU A CD1 1 
ATOM   361  C  CD2 . LEU A 1 100 ? 116.769 131.346 142.898 1.00 111.99 ? 100 LEU A CD2 1 
ATOM   362  N  N   . ALA A 1 101 ? 112.568 134.431 142.142 1.00 109.29 ? 101 ALA A N   1 
ATOM   363  C  CA  . ALA A 1 101 ? 111.776 135.049 141.085 1.00 110.75 ? 101 ALA A CA  1 
ATOM   364  C  C   . ALA A 1 101 ? 112.532 136.204 140.444 1.00 118.24 ? 101 ALA A C   1 
ATOM   365  O  O   . ALA A 1 101 ? 112.505 136.378 139.218 1.00 123.61 ? 101 ALA A O   1 
ATOM   366  C  CB  . ALA A 1 101 ? 110.438 135.525 141.646 1.00 111.55 ? 101 ALA A CB  1 
ATOM   367  N  N   . ILE A 1 102 ? 113.216 137.004 141.261 1.00 112.47 ? 102 ILE A N   1 
ATOM   368  C  CA  . ILE A 1 102 ? 114.040 138.083 140.731 1.00 107.78 ? 102 ILE A CA  1 
ATOM   369  C  C   . ILE A 1 102 ? 115.196 137.516 139.920 1.00 113.09 ? 102 ILE A C   1 
ATOM   370  O  O   . ILE A 1 102 ? 115.613 138.103 138.917 1.00 120.75 ? 102 ILE A O   1 
ATOM   371  C  CB  . ILE A 1 102 ? 114.525 138.989 141.874 1.00 109.37 ? 102 ILE A CB  1 
ATOM   372  C  CG1 . ILE A 1 102 ? 113.350 139.337 142.787 1.00 105.36 ? 102 ILE A CG1 1 
ATOM   373  C  CG2 . ILE A 1 102 ? 115.152 140.250 141.322 1.00 116.77 ? 102 ILE A CG2 1 
ATOM   374  C  CD1 . ILE A 1 102 ? 113.641 140.437 143.766 1.00 114.20 ? 102 ILE A CD1 1 
ATOM   375  N  N   . MET A 1 103 ? 115.728 136.365 140.336 1.00 117.25 ? 103 MET A N   1 
ATOM   376  C  CA  . MET A 1 103 ? 116.682 135.651 139.492 1.00 114.37 ? 103 MET A CA  1 
ATOM   377  C  C   . MET A 1 103 ? 116.071 135.272 138.153 1.00 116.35 ? 103 MET A C   1 
ATOM   378  O  O   . MET A 1 103 ? 116.744 135.342 137.123 1.00 128.16 ? 103 MET A O   1 
ATOM   379  C  CB  . MET A 1 103 ? 117.206 134.409 140.210 1.00 123.88 ? 103 MET A CB  1 
ATOM   380  C  CG  . MET A 1 103 ? 118.189 134.681 141.326 1.00 125.68 ? 103 MET A CG  1 
ATOM   381  S  SD  . MET A 1 103 ? 119.253 136.072 140.912 1.00 138.09 ? 103 MET A SD  1 
ATOM   382  C  CE  . MET A 1 103 ? 118.865 137.192 142.238 1.00 122.51 ? 103 MET A CE  1 
ATOM   383  N  N   . THR A 1 104 ? 114.805 134.857 138.140 1.00 112.84 ? 104 THR A N   1 
ATOM   384  C  CA  . THR A 1 104 ? 114.174 134.514 136.869 1.00 117.20 ? 104 THR A CA  1 
ATOM   385  C  C   . THR A 1 104 ? 114.043 135.737 135.969 1.00 123.88 ? 104 THR A C   1 
ATOM   386  O  O   . THR A 1 104 ? 114.322 135.665 134.765 1.00 126.87 ? 104 THR A O   1 
ATOM   387  C  CB  . THR A 1 104 ? 112.809 133.878 137.112 1.00 121.64 ? 104 THR A CB  1 
ATOM   388  O  OG1 . THR A 1 104 ? 112.914 132.909 138.160 1.00 129.64 ? 104 THR A OG1 1 
ATOM   389  C  CG2 . THR A 1 104 ? 112.322 133.191 135.853 1.00 122.31 ? 104 THR A CG2 1 
ATOM   390  N  N   . ASP A 1 105 ? 113.630 136.872 136.536 1.00 124.54 ? 105 ASP A N   1 
ATOM   391  C  CA  . ASP A 1 105 ? 113.527 138.092 135.740 1.00 116.46 ? 105 ASP A CA  1 
ATOM   392  C  C   . ASP A 1 105 ? 114.891 138.537 135.227 1.00 119.65 ? 105 ASP A C   1 
ATOM   393  O  O   . ASP A 1 105 ? 115.026 138.953 134.069 1.00 124.97 ? 105 ASP A O   1 
ATOM   394  C  CB  . ASP A 1 105 ? 112.875 139.198 136.564 1.00 118.56 ? 105 ASP A CB  1 
ATOM   395  C  CG  . ASP A 1 105 ? 111.768 139.905 135.813 1.00 129.99 ? 105 ASP A CG  1 
ATOM   396  O  OD1 . ASP A 1 105 ? 111.272 140.935 136.314 1.00 133.80 ? 105 ASP A OD1 1 
ATOM   397  O  OD2 . ASP A 1 105 ? 111.397 139.436 134.717 1.00 132.86 ? 105 ASP A OD2 1 
ATOM   398  N  N   . ALA A 1 106 ? 115.917 138.453 136.075 1.00 117.00 ? 106 ALA A N   1 
ATOM   399  C  CA  . ALA A 1 106 ? 117.262 138.819 135.652 1.00 112.49 ? 106 ALA A CA  1 
ATOM   400  C  C   . ALA A 1 106 ? 117.779 137.872 134.579 1.00 112.97 ? 106 ALA A C   1 
ATOM   401  O  O   . ALA A 1 106 ? 118.510 138.287 133.677 1.00 119.98 ? 106 ALA A O   1 
ATOM   402  C  CB  . ALA A 1 106 ? 118.198 138.835 136.856 1.00 109.05 ? 106 ALA A CB  1 
ATOM   403  N  N   . ALA A 1 107 ? 117.417 136.593 134.664 1.00 108.73 ? 107 ALA A N   1 
ATOM   404  C  CA  . ALA A 1 107 ? 117.789 135.646 133.620 1.00 106.50 ? 107 ALA A CA  1 
ATOM   405  C  C   . ALA A 1 107 ? 117.110 135.990 132.304 1.00 113.93 ? 107 ALA A C   1 
ATOM   406  O  O   . ALA A 1 107 ? 117.715 135.863 131.234 1.00 118.58 ? 107 ALA A O   1 
ATOM   407  C  CB  . ALA A 1 107 ? 117.436 134.226 134.053 1.00 107.78 ? 107 ALA A CB  1 
ATOM   408  N  N   . HIS A 1 108 ? 115.848 136.417 132.359 1.00 113.43 ? 108 HIS A N   1 
ATOM   409  C  CA  . HIS A 1 108 ? 115.184 136.859 131.136 1.00 114.10 ? 108 HIS A CA  1 
ATOM   410  C  C   . HIS A 1 108 ? 115.876 138.081 130.547 1.00 116.53 ? 108 HIS A C   1 
ATOM   411  O  O   . HIS A 1 108 ? 116.052 138.180 129.326 1.00 119.07 ? 108 HIS A O   1 
ATOM   412  C  CB  . HIS A 1 108 ? 113.715 137.167 131.403 1.00 113.22 ? 108 HIS A CB  1 
ATOM   413  C  CG  . HIS A 1 108 ? 113.033 137.841 130.257 1.00 116.39 ? 108 HIS A CG  1 
ATOM   414  N  ND1 . HIS A 1 108 ? 112.948 137.270 129.006 1.00 118.08 ? 108 HIS A ND1 1 
ATOM   415  C  CD2 . HIS A 1 108 ? 112.417 139.042 130.165 1.00 115.61 ? 108 HIS A CD2 1 
ATOM   416  C  CE1 . HIS A 1 108 ? 112.303 138.088 128.194 1.00 115.71 ? 108 HIS A CE1 1 
ATOM   417  N  NE2 . HIS A 1 108 ? 111.968 139.169 128.873 1.00 121.01 ? 108 HIS A NE2 1 
ATOM   418  N  N   . LEU A 1 109 ? 116.269 139.028 131.400 1.00 114.74 ? 109 LEU A N   1 
ATOM   419  C  CA  . LEU A 1 109 ? 117.000 140.195 130.914 1.00 108.55 ? 109 LEU A CA  1 
ATOM   420  C  C   . LEU A 1 109 ? 118.344 139.796 130.320 1.00 111.82 ? 109 LEU A C   1 
ATOM   421  O  O   . LEU A 1 109 ? 118.795 140.386 129.334 1.00 117.96 ? 109 LEU A O   1 
ATOM   422  C  CB  . LEU A 1 109 ? 117.193 141.205 132.040 1.00 105.43 ? 109 LEU A CB  1 
ATOM   423  C  CG  . LEU A 1 109 ? 115.994 142.106 132.313 1.00 106.98 ? 109 LEU A CG  1 
ATOM   424  C  CD1 . LEU A 1 109 ? 116.195 142.859 133.608 1.00 112.05 ? 109 LEU A CD1 1 
ATOM   425  C  CD2 . LEU A 1 109 ? 115.782 143.064 131.158 1.00 108.32 ? 109 LEU A CD2 1 
ATOM   426  N  N   . LEU A 1 110 ? 119.004 138.806 130.920 1.00 115.36 ? 110 LEU A N   1 
ATOM   427  C  CA  . LEU A 1 110 ? 120.252 138.296 130.365 1.00 111.12 ? 110 LEU A CA  1 
ATOM   428  C  C   . LEU A 1 110 ? 120.022 137.678 128.996 1.00 113.49 ? 110 LEU A C   1 
ATOM   429  O  O   . LEU A 1 110 ? 120.843 137.836 128.090 1.00 114.67 ? 110 LEU A O   1 
ATOM   430  C  CB  . LEU A 1 110 ? 120.869 137.281 131.330 1.00 115.85 ? 110 LEU A CB  1 
ATOM   431  C  CG  . LEU A 1 110 ? 122.323 136.820 131.175 1.00 121.59 ? 110 LEU A CG  1 
ATOM   432  C  CD1 . LEU A 1 110 ? 122.790 136.192 132.474 1.00 115.56 ? 110 LEU A CD1 1 
ATOM   433  C  CD2 . LEU A 1 110 ? 122.502 135.824 130.041 1.00 117.94 ? 110 LEU A CD2 1 
ATOM   434  N  N   . ALA A 1 111 ? 118.913 136.957 128.832 1.00 116.87 ? 111 ALA A N   1 
ATOM   435  C  CA  . ALA A 1 111 ? 118.580 136.405 127.523 1.00 114.97 ? 111 ALA A CA  1 
ATOM   436  C  C   . ALA A 1 111 ? 118.353 137.512 126.503 1.00 116.68 ? 111 ALA A C   1 
ATOM   437  O  O   . ALA A 1 111 ? 118.811 137.417 125.358 1.00 117.54 ? 111 ALA A O   1 
ATOM   438  C  CB  . ALA A 1 111 ? 117.347 135.511 127.628 1.00 114.71 ? 111 ALA A CB  1 
ATOM   439  N  N   . ASP A 1 112 ? 117.645 138.571 126.902 1.00 127.33 ? 112 ASP A N   1 
ATOM   440  C  CA  . ASP A 1 112 ? 117.425 139.702 126.004 1.00 124.14 ? 112 ASP A CA  1 
ATOM   441  C  C   . ASP A 1 112 ? 118.749 140.342 125.600 1.00 124.00 ? 112 ASP A C   1 
ATOM   442  O  O   . ASP A 1 112 ? 118.987 140.625 124.417 1.00 126.60 ? 112 ASP A O   1 
ATOM   443  C  CB  . ASP A 1 112 ? 116.508 140.729 126.676 1.00 123.59 ? 112 ASP A CB  1 
ATOM   444  C  CG  . ASP A 1 112 ? 115.058 140.275 126.728 1.00 132.02 ? 112 ASP A CG  1 
ATOM   445  O  OD1 . ASP A 1 112 ? 114.807 139.079 126.479 1.00 135.66 ? 112 ASP A OD1 1 
ATOM   446  O  OD2 . ASP A 1 112 ? 114.169 141.102 127.037 1.00 133.35 ? 112 ASP A OD2 1 
ATOM   447  N  N   . VAL A 1 113 ? 119.634 140.557 126.576 1.00 120.59 ? 113 VAL A N   1 
ATOM   448  C  CA  . VAL A 1 113 ? 120.936 141.160 126.306 1.00 115.76 ? 113 VAL A CA  1 
ATOM   449  C  C   . VAL A 1 113 ? 121.750 140.277 125.374 1.00 118.69 ? 113 VAL A C   1 
ATOM   450  O  O   . VAL A 1 113 ? 122.385 140.764 124.435 1.00 123.74 ? 113 VAL A O   1 
ATOM   451  C  CB  . VAL A 1 113 ? 121.686 141.425 127.625 1.00 118.58 ? 113 VAL A CB  1 
ATOM   452  C  CG1 . VAL A 1 113 ? 123.185 141.450 127.393 1.00 116.35 ? 113 VAL A CG1 1 
ATOM   453  C  CG2 . VAL A 1 113 ? 121.235 142.727 128.237 1.00 118.82 ? 113 VAL A CG2 1 
ATOM   454  N  N   . GLY A 1 114 ? 121.754 138.968 125.625 1.00 123.74 ? 114 GLY A N   1 
ATOM   455  C  CA  . GLY A 1 114 ? 122.505 138.064 124.774 1.00 119.22 ? 114 GLY A CA  1 
ATOM   456  C  C   . GLY A 1 114 ? 121.978 138.030 123.355 1.00 117.45 ? 114 GLY A C   1 
ATOM   457  O  O   . GLY A 1 114 ? 122.752 137.993 122.399 1.00 119.42 ? 114 GLY A O   1 
ATOM   458  N  N   . SER A 1 115 ? 120.654 138.046 123.197 1.00 119.42 ? 115 SER A N   1 
ATOM   459  C  CA  . SER A 1 115 ? 120.078 138.071 121.858 1.00 122.10 ? 115 SER A CA  1 
ATOM   460  C  C   . SER A 1 115 ? 120.456 139.349 121.120 1.00 122.12 ? 115 SER A C   1 
ATOM   461  O  O   . SER A 1 115 ? 120.839 139.305 119.944 1.00 124.35 ? 115 SER A O   1 
ATOM   462  C  CB  . SER A 1 115 ? 118.560 137.924 121.936 1.00 123.26 ? 115 SER A CB  1 
ATOM   463  O  OG  . SER A 1 115 ? 117.925 139.187 121.867 1.00 125.88 ? 115 SER A OG  1 
ATOM   464  N  N   . MET A 1 116 ? 120.371 140.497 121.795 1.00 127.21 ? 116 MET A N   1 
ATOM   465  C  CA  . MET A 1 116 ? 120.723 141.749 121.131 1.00 124.75 ? 116 MET A CA  1 
ATOM   466  C  C   . MET A 1 116 ? 122.213 141.811 120.810 1.00 128.45 ? 116 MET A C   1 
ATOM   467  O  O   . MET A 1 116 ? 122.604 142.318 119.753 1.00 130.04 ? 116 MET A O   1 
ATOM   468  C  CB  . MET A 1 116 ? 120.307 142.943 121.985 1.00 125.63 ? 116 MET A CB  1 
ATOM   469  C  CG  . MET A 1 116 ? 118.969 143.535 121.592 1.00 124.08 ? 116 MET A CG  1 
ATOM   470  S  SD  . MET A 1 116 ? 118.297 144.649 122.834 1.00 137.33 ? 116 MET A SD  1 
ATOM   471  C  CE  . MET A 1 116 ? 118.653 143.755 124.338 1.00 132.88 ? 116 MET A CE  1 
ATOM   472  N  N   . MET A 1 117 ? 123.059 141.306 121.708 1.00 134.50 ? 117 MET A N   1 
ATOM   473  C  CA  . MET A 1 117 ? 124.495 141.285 121.448 1.00 128.55 ? 117 MET A CA  1 
ATOM   474  C  C   . MET A 1 117 ? 124.834 140.361 120.290 1.00 129.82 ? 117 MET A C   1 
ATOM   475  O  O   . MET A 1 117 ? 125.700 140.679 119.470 1.00 134.58 ? 117 MET A O   1 
ATOM   476  C  CB  . MET A 1 117 ? 125.251 140.866 122.706 1.00 128.39 ? 117 MET A CB  1 
ATOM   477  C  CG  . MET A 1 117 ? 125.619 142.019 123.618 1.00 132.50 ? 117 MET A CG  1 
ATOM   478  S  SD  . MET A 1 117 ? 127.003 141.641 124.709 1.00 150.73 ? 117 MET A SD  1 
ATOM   479  C  CE  . MET A 1 117 ? 126.983 139.851 124.688 1.00 132.87 ? 117 MET A CE  1 
ATOM   480  N  N   . GLY A 1 118 ? 124.175 139.205 120.213 1.00 118.89 ? 118 GLY A N   1 
ATOM   481  C  CA  . GLY A 1 118 ? 124.371 138.333 119.070 1.00 119.17 ? 118 GLY A CA  1 
ATOM   482  C  C   . GLY A 1 118 ? 123.920 138.976 117.776 1.00 122.62 ? 118 GLY A C   1 
ATOM   483  O  O   . GLY A 1 118 ? 124.561 138.816 116.736 1.00 125.17 ? 118 GLY A O   1 
ATOM   484  N  N   . SER A 1 119 ? 122.811 139.717 117.822 1.00 123.72 ? 119 SER A N   1 
ATOM   485  C  CA  . SER A 1 119 ? 122.365 140.444 116.639 1.00 119.12 ? 119 SER A CA  1 
ATOM   486  C  C   . SER A 1 119 ? 123.388 141.490 116.217 1.00 118.24 ? 119 SER A C   1 
ATOM   487  O  O   . SER A 1 119 ? 123.677 141.643 115.026 1.00 120.35 ? 119 SER A O   1 
ATOM   488  C  CB  . SER A 1 119 ? 121.010 141.095 116.906 1.00 123.39 ? 119 SER A CB  1 
ATOM   489  O  OG  . SER A 1 119 ? 120.744 142.112 115.959 1.00 129.88 ? 119 SER A OG  1 
ATOM   490  N  N   . LEU A 1 120 ? 123.950 142.219 117.183 1.00 118.42 ? 120 LEU A N   1 
ATOM   491  C  CA  . LEU A 1 120 ? 124.972 143.214 116.871 1.00 119.65 ? 120 LEU A CA  1 
ATOM   492  C  C   . LEU A 1 120 ? 126.215 142.565 116.277 1.00 120.04 ? 120 LEU A C   1 
ATOM   493  O  O   . LEU A 1 120 ? 126.791 143.072 115.307 1.00 123.67 ? 120 LEU A O   1 
ATOM   494  C  CB  . LEU A 1 120 ? 125.338 143.994 118.131 1.00 120.21 ? 120 LEU A CB  1 
ATOM   495  C  CG  . LEU A 1 120 ? 124.592 145.295 118.401 1.00 119.80 ? 120 LEU A CG  1 
ATOM   496  C  CD1 . LEU A 1 120 ? 124.929 145.792 119.788 1.00 120.47 ? 120 LEU A CD1 1 
ATOM   497  C  CD2 . LEU A 1 120 ? 124.942 146.336 117.358 1.00 124.25 ? 120 LEU A CD2 1 
ATOM   498  N  N   . PHE A 1 121 ? 126.650 141.446 116.858 1.00 124.91 ? 121 PHE A N   1 
ATOM   499  C  CA  . PHE A 1 121 ? 127.827 140.753 116.352 1.00 124.60 ? 121 PHE A CA  1 
ATOM   500  C  C   . PHE A 1 121 ? 127.593 140.227 114.944 1.00 126.61 ? 121 PHE A C   1 
ATOM   501  O  O   . PHE A 1 121 ? 128.476 140.315 114.087 1.00 130.28 ? 121 PHE A O   1 
ATOM   502  C  CB  . PHE A 1 121 ? 128.207 139.614 117.294 1.00 125.77 ? 121 PHE A CB  1 
ATOM   503  C  CG  . PHE A 1 121 ? 129.503 138.949 116.945 1.00 132.99 ? 121 PHE A CG  1 
ATOM   504  C  CD1 . PHE A 1 121 ? 130.706 139.597 117.156 1.00 132.22 ? 121 PHE A CD1 1 
ATOM   505  C  CD2 . PHE A 1 121 ? 129.518 137.675 116.405 1.00 130.48 ? 121 PHE A CD2 1 
ATOM   506  C  CE1 . PHE A 1 121 ? 131.901 138.987 116.834 1.00 132.08 ? 121 PHE A CE1 1 
ATOM   507  C  CE2 . PHE A 1 121 ? 130.710 137.061 116.082 1.00 130.24 ? 121 PHE A CE2 1 
ATOM   508  C  CZ  . PHE A 1 121 ? 131.903 137.718 116.297 1.00 132.99 ? 121 PHE A CZ  1 
ATOM   509  N  N   . SER A 1 122 ? 126.406 139.675 114.686 1.00 125.25 ? 122 SER A N   1 
ATOM   510  C  CA  . SER A 1 122 ? 126.085 139.210 113.343 1.00 123.92 ? 122 SER A CA  1 
ATOM   511  C  C   . SER A 1 122 ? 126.029 140.368 112.357 1.00 123.25 ? 122 SER A C   1 
ATOM   512  O  O   . SER A 1 122 ? 126.459 140.230 111.209 1.00 128.36 ? 122 SER A O   1 
ATOM   513  C  CB  . SER A 1 122 ? 124.759 138.456 113.353 1.00 126.65 ? 122 SER A CB  1 
ATOM   514  O  OG  . SER A 1 122 ? 123.699 139.302 112.948 1.00 134.21 ? 122 SER A OG  1 
ATOM   515  N  N   . LEU A 1 123 ? 125.490 141.511 112.781 1.00 119.11 ? 123 LEU A N   1 
ATOM   516  C  CA  . LEU A 1 123 ? 125.450 142.678 111.908 1.00 119.73 ? 123 LEU A CA  1 
ATOM   517  C  C   . LEU A 1 123 ? 126.853 143.152 111.561 1.00 119.71 ? 123 LEU A C   1 
ATOM   518  O  O   . LEU A 1 123 ? 127.125 143.531 110.416 1.00 121.24 ? 123 LEU A O   1 
ATOM   519  C  CB  . LEU A 1 123 ? 124.655 143.799 112.574 1.00 124.61 ? 123 LEU A CB  1 
ATOM   520  C  CG  . LEU A 1 123 ? 124.085 144.874 111.653 1.00 126.48 ? 123 LEU A CG  1 
ATOM   521  C  CD1 . LEU A 1 123 ? 122.663 145.212 112.057 1.00 122.02 ? 123 LEU A CD1 1 
ATOM   522  C  CD2 . LEU A 1 123 ? 124.959 146.113 111.684 1.00 123.92 ? 123 LEU A CD2 1 
ATOM   523  N  N   . TRP A 1 124 ? 127.756 143.153 112.541 1.00 120.30 ? 124 TRP A N   1 
ATOM   524  C  CA  . TRP A 1 124 ? 129.139 143.525 112.263 1.00 120.41 ? 124 TRP A CA  1 
ATOM   525  C  C   . TRP A 1 124 ? 129.815 142.509 111.352 1.00 123.02 ? 124 TRP A C   1 
ATOM   526  O  O   . TRP A 1 124 ? 130.573 142.883 110.451 1.00 126.19 ? 124 TRP A O   1 
ATOM   527  C  CB  . TRP A 1 124 ? 129.918 143.668 113.566 1.00 122.35 ? 124 TRP A CB  1 
ATOM   528  C  CG  . TRP A 1 124 ? 131.386 143.816 113.355 1.00 126.25 ? 124 TRP A CG  1 
ATOM   529  C  CD1 . TRP A 1 124 ? 132.026 144.871 112.780 1.00 126.93 ? 124 TRP A CD1 1 
ATOM   530  C  CD2 . TRP A 1 124 ? 132.403 142.877 113.716 1.00 127.28 ? 124 TRP A CD2 1 
ATOM   531  N  NE1 . TRP A 1 124 ? 133.380 144.648 112.761 1.00 128.66 ? 124 TRP A NE1 1 
ATOM   532  C  CE2 . TRP A 1 124 ? 133.637 143.430 113.331 1.00 127.21 ? 124 TRP A CE2 1 
ATOM   533  C  CE3 . TRP A 1 124 ? 132.389 141.622 114.331 1.00 123.23 ? 124 TRP A CE3 1 
ATOM   534  C  CZ2 . TRP A 1 124 ? 134.845 142.773 113.538 1.00 125.22 ? 124 TRP A CZ2 1 
ATOM   535  C  CZ3 . TRP A 1 124 ? 133.589 140.972 114.535 1.00 125.30 ? 124 TRP A CZ3 1 
ATOM   536  C  CH2 . TRP A 1 124 ? 134.799 141.548 114.140 1.00 129.09 ? 124 TRP A CH2 1 
ATOM   537  N  N   . LEU A 1 125 ? 129.559 141.220 111.575 1.00 121.49 ? 125 LEU A N   1 
ATOM   538  C  CA  . LEU A 1 125 ? 130.213 140.183 110.787 1.00 115.81 ? 125 LEU A CA  1 
ATOM   539  C  C   . LEU A 1 125 ? 129.712 140.157 109.352 1.00 119.33 ? 125 LEU A C   1 
ATOM   540  O  O   . LEU A 1 125 ? 130.491 139.880 108.434 1.00 123.51 ? 125 LEU A O   1 
ATOM   541  C  CB  . LEU A 1 125 ? 130.002 138.819 111.437 1.00 114.99 ? 125 LEU A CB  1 
ATOM   542  C  CG  . LEU A 1 125 ? 131.176 138.253 112.232 1.00 116.38 ? 125 LEU A CG  1 
ATOM   543  C  CD1 . LEU A 1 125 ? 130.988 136.767 112.458 1.00 120.04 ? 125 LEU A CD1 1 
ATOM   544  C  CD2 . LEU A 1 125 ? 132.479 138.523 111.517 1.00 118.84 ? 125 LEU A CD2 1 
ATOM   545  N  N   . SER A 1 126 ? 128.432 140.447 109.132 1.00 131.01 ? 126 SER A N   1 
ATOM   546  C  CA  . SER A 1 126 ? 127.870 140.374 107.791 1.00 130.52 ? 126 SER A CA  1 
ATOM   547  C  C   . SER A 1 126 ? 128.217 141.625 106.999 1.00 130.89 ? 126 SER A C   1 
ATOM   548  O  O   . SER A 1 126 ? 127.363 142.205 106.323 1.00 134.34 ? 126 SER A O   1 
ATOM   549  C  CB  . SER A 1 126 ? 126.355 140.190 107.854 1.00 133.27 ? 126 SER A CB  1 
ATOM   550  O  OG  . SER A 1 126 ? 125.701 141.443 107.935 1.00 138.37 ? 126 SER A OG  1 
ATOM   551  N  N   . THR A 1 127 ? 129.477 142.038 107.079 1.00 126.32 ? 127 THR A N   1 
ATOM   552  C  CA  . THR A 1 127 ? 130.020 143.075 106.213 1.00 130.48 ? 127 THR A CA  1 
ATOM   553  C  C   . THR A 1 127 ? 131.372 142.712 105.630 1.00 136.21 ? 127 THR A C   1 
ATOM   554  O  O   . THR A 1 127 ? 131.812 143.379 104.688 1.00 134.39 ? 127 THR A O   1 
ATOM   555  C  CB  . THR A 1 127 ? 130.142 144.406 106.968 1.00 132.19 ? 127 THR A CB  1 
ATOM   556  O  OG1 . THR A 1 127 ? 130.107 145.491 106.035 1.00 135.94 ? 127 THR A OG1 1 
ATOM   557  C  CG2 . THR A 1 127 ? 131.443 144.465 107.755 1.00 129.95 ? 127 THR A CG2 1 
ATOM   558  N  N   . ARG A 1 128 ? 132.042 141.686 106.142 1.00 131.95 ? 128 ARG A N   1 
ATOM   559  C  CA  . ARG A 1 128 ? 133.309 141.267 105.575 1.00 129.26 ? 128 ARG A CA  1 
ATOM   560  C  C   . ARG A 1 128 ? 133.070 140.506 104.275 1.00 126.88 ? 128 ARG A C   1 
ATOM   561  O  O   . ARG A 1 128 ? 132.078 139.783 104.151 1.00 127.52 ? 128 ARG A O   1 
ATOM   562  C  CB  . ARG A 1 128 ? 134.070 140.389 106.564 1.00 124.71 ? 128 ARG A CB  1 
ATOM   563  C  CG  . ARG A 1 128 ? 134.351 141.067 107.886 1.00 123.75 ? 128 ARG A CG  1 
ATOM   564  C  CD  . ARG A 1 128 ? 134.526 140.051 108.993 1.00 128.99 ? 128 ARG A CD  1 
ATOM   565  N  NE  . ARG A 1 128 ? 135.813 139.376 108.900 1.00 132.06 ? 128 ARG A NE  1 
ATOM   566  C  CZ  . ARG A 1 128 ? 136.363 138.669 109.878 1.00 131.72 ? 128 ARG A CZ  1 
ATOM   567  N  NH1 . ARG A 1 128 ? 135.762 138.521 111.046 1.00 126.91 ? 128 ARG A NH1 1 
ATOM   568  N  NH2 . ARG A 1 128 ? 137.548 138.100 109.679 1.00 130.43 ? 128 ARG A NH2 1 
ATOM   569  N  N   . PRO A 1 129 ? 133.952 140.650 103.292 1.00 116.06 ? 129 PRO A N   1 
ATOM   570  C  CA  . PRO A 1 129 ? 133.784 139.904 102.044 1.00 117.91 ? 129 PRO A CA  1 
ATOM   571  C  C   . PRO A 1 129 ? 134.004 138.417 102.259 1.00 120.36 ? 129 PRO A C   1 
ATOM   572  O  O   . PRO A 1 129 ? 134.702 137.995 103.183 1.00 121.00 ? 129 PRO A O   1 
ATOM   573  C  CB  . PRO A 1 129 ? 134.858 140.499 101.129 1.00 120.04 ? 129 PRO A CB  1 
ATOM   574  C  CG  . PRO A 1 129 ? 135.892 141.018 102.063 1.00 118.16 ? 129 PRO A CG  1 
ATOM   575  C  CD  . PRO A 1 129 ? 135.156 141.496 103.277 1.00 115.61 ? 129 PRO A CD  1 
ATOM   576  N  N   . ALA A 1 130 ? 133.380 137.620 101.397 1.00 113.28 ? 130 ALA A N   1 
ATOM   577  C  CA  . ALA A 1 130 ? 133.563 136.177 101.450 1.00 108.31 ? 130 ALA A CA  1 
ATOM   578  C  C   . ALA A 1 130 ? 135.015 135.822 101.165 1.00 113.03 ? 130 ALA A C   1 
ATOM   579  O  O   . ALA A 1 130 ? 135.627 136.356 100.237 1.00 113.86 ? 130 ALA A O   1 
ATOM   580  C  CB  . ALA A 1 130 ? 132.641 135.492 100.445 1.00 104.61 ? 130 ALA A CB  1 
ATOM   581  N  N   . THR A 1 131 ? 135.567 134.922 101.970 1.00 118.03 ? 131 THR A N   1 
ATOM   582  C  CA  . THR A 1 131 ? 136.946 134.493 101.828 1.00 115.05 ? 131 THR A CA  1 
ATOM   583  C  C   . THR A 1 131 ? 137.003 133.153 101.100 1.00 114.74 ? 131 THR A C   1 
ATOM   584  O  O   . THR A 1 131 ? 135.988 132.603 100.670 1.00 115.69 ? 131 THR A O   1 
ATOM   585  C  CB  . THR A 1 131 ? 137.622 134.403 103.197 1.00 115.07 ? 131 THR A CB  1 
ATOM   586  O  OG1 . THR A 1 131 ? 137.169 133.228 103.877 1.00 119.27 ? 131 THR A OG1 1 
ATOM   587  C  CG2 . THR A 1 131 ? 137.280 135.619 104.033 1.00 119.80 ? 131 THR A CG2 1 
ATOM   588  N  N   . ARG A 1 132 ? 138.216 132.626 100.956 1.00 118.97 ? 132 ARG A N   1 
ATOM   589  C  CA  . ARG A 1 132 ? 138.403 131.327 100.327 1.00 116.52 ? 132 ARG A CA  1 
ATOM   590  C  C   . ARG A 1 132 ? 138.053 130.171 101.248 1.00 119.73 ? 132 ARG A C   1 
ATOM   591  O  O   . ARG A 1 132 ? 137.904 129.043 100.769 1.00 125.80 ? 132 ARG A O   1 
ATOM   592  C  CB  . ARG A 1 132 ? 139.844 131.182 99.842  1.00 116.47 ? 132 ARG A CB  1 
ATOM   593  C  CG  . ARG A 1 132 ? 140.183 132.093 98.683  1.00 121.88 ? 132 ARG A CG  1 
ATOM   594  C  CD  . ARG A 1 132 ? 141.672 132.337 98.591  1.00 125.29 ? 132 ARG A CD  1 
ATOM   595  N  NE  . ARG A 1 132 ? 142.223 131.856 97.331  1.00 127.73 ? 132 ARG A NE  1 
ATOM   596  C  CZ  . ARG A 1 132 ? 142.319 132.586 96.230  1.00 131.29 ? 132 ARG A CZ  1 
ATOM   597  N  NH1 . ARG A 1 132 ? 141.908 133.842 96.196  1.00 132.38 ? 132 ARG A NH1 1 
ATOM   598  N  NH2 . ARG A 1 132 ? 142.840 132.042 95.134  1.00 128.76 ? 132 ARG A NH2 1 
ATOM   599  N  N   . THR A 1 133 ? 137.925 130.417 102.550 1.00 109.55 ? 133 THR A N   1 
ATOM   600  C  CA  . THR A 1 133 ? 137.483 129.394 103.485 1.00 109.66 ? 133 THR A CA  1 
ATOM   601  C  C   . THR A 1 133 ? 136.021 129.539 103.873 1.00 110.01 ? 133 THR A C   1 
ATOM   602  O  O   . THR A 1 133 ? 135.441 128.589 104.407 1.00 111.64 ? 133 THR A O   1 
ATOM   603  C  CB  . THR A 1 133 ? 138.341 129.423 104.753 1.00 112.14 ? 133 THR A CB  1 
ATOM   604  O  OG1 . THR A 1 133 ? 138.261 130.719 105.355 1.00 116.86 ? 133 THR A OG1 1 
ATOM   605  C  CG2 . THR A 1 133 ? 139.788 129.121 104.416 1.00 111.93 ? 133 THR A CG2 1 
ATOM   606  N  N   . MET A 1 134 ? 135.418 130.700 103.623 1.00 107.23 ? 134 MET A N   1 
ATOM   607  C  CA  . MET A 1 134 ? 134.000 130.947 103.878 1.00 101.21 ? 134 MET A CA  1 
ATOM   608  C  C   . MET A 1 134 ? 133.433 131.511 102.582 1.00 106.10 ? 134 MET A C   1 
ATOM   609  O  O   . MET A 1 134 ? 133.362 132.729 102.405 1.00 112.67 ? 134 MET A O   1 
ATOM   610  C  CB  . MET A 1 134 ? 133.805 131.899 105.049 1.00 99.85  ? 134 MET A CB  1 
ATOM   611  C  CG  . MET A 1 134 ? 134.556 131.494 106.303 1.00 109.46 ? 134 MET A CG  1 
ATOM   612  S  SD  . MET A 1 134 ? 133.639 130.349 107.341 1.00 123.31 ? 134 MET A SD  1 
ATOM   613  C  CE  . MET A 1 134 ? 131.985 130.972 107.112 1.00 113.83 ? 134 MET A CE  1 
ATOM   614  N  N   . THR A 1 135 ? 133.032 130.620 101.676 1.00 103.87 ? 135 THR A N   1 
ATOM   615  C  CA  . THR A 1 135 ? 132.622 131.049 100.344 1.00 98.77  ? 135 THR A CA  1 
ATOM   616  C  C   . THR A 1 135 ? 131.284 131.773 100.375 1.00 96.90  ? 135 THR A C   1 
ATOM   617  O  O   . THR A 1 135 ? 131.058 132.704 99.594  1.00 97.88  ? 135 THR A O   1 
ATOM   618  C  CB  . THR A 1 135 ? 132.556 129.846 99.408  1.00 97.14  ? 135 THR A CB  1 
ATOM   619  O  OG1 . THR A 1 135 ? 131.974 128.738 100.101 1.00 104.89 ? 135 THR A OG1 1 
ATOM   620  C  CG2 . THR A 1 135 ? 133.947 129.463 98.947  1.00 96.46  ? 135 THR A CG2 1 
ATOM   621  N  N   . PHE A 1 136 ? 130.382 131.359 101.260 1.00 97.82  ? 136 PHE A N   1 
ATOM   622  C  CA  . PHE A 1 136 ? 129.058 131.958 101.328 1.00 93.91  ? 136 PHE A CA  1 
ATOM   623  C  C   . PHE A 1 136 ? 129.033 133.272 102.094 1.00 101.23 ? 136 PHE A C   1 
ATOM   624  O  O   . PHE A 1 136 ? 128.048 134.010 101.989 1.00 110.34 ? 136 PHE A O   1 
ATOM   625  C  CB  . PHE A 1 136 ? 128.077 130.982 101.975 1.00 92.66  ? 136 PHE A CB  1 
ATOM   626  C  CG  . PHE A 1 136 ? 127.520 129.967 101.027 1.00 98.33  ? 136 PHE A CG  1 
ATOM   627  C  CD1 . PHE A 1 136 ? 126.499 130.299 100.160 1.00 98.44  ? 136 PHE A CD1 1 
ATOM   628  C  CD2 . PHE A 1 136 ? 128.016 128.679 101.005 1.00 102.49 ? 136 PHE A CD2 1 
ATOM   629  C  CE1 . PHE A 1 136 ? 125.985 129.365 99.290  1.00 98.02  ? 136 PHE A CE1 1 
ATOM   630  C  CE2 . PHE A 1 136 ? 127.506 127.744 100.138 1.00 101.26 ? 136 PHE A CE2 1 
ATOM   631  C  CZ  . PHE A 1 136 ? 126.489 128.087 99.280  1.00 94.97  ? 136 PHE A CZ  1 
ATOM   632  N  N   . GLY A 1 137 ? 130.077 133.583 102.853 1.00 100.08 ? 137 GLY A N   1 
ATOM   633  C  CA  . GLY A 1 137 ? 130.075 134.770 103.680 1.00 97.10  ? 137 GLY A CA  1 
ATOM   634  C  C   . GLY A 1 137 ? 130.010 134.425 105.151 1.00 102.33 ? 137 GLY A C   1 
ATOM   635  O  O   . GLY A 1 137 ? 130.505 133.375 105.564 1.00 111.66 ? 137 GLY A O   1 
ATOM   636  N  N   . TRP A 1 138 ? 129.392 135.290 105.953 1.00 98.72  ? 138 TRP A N   1 
ATOM   637  C  CA  . TRP A 1 138 ? 129.297 135.076 107.391 1.00 100.41 ? 138 TRP A CA  1 
ATOM   638  C  C   . TRP A 1 138 ? 127.858 135.187 107.873 1.00 104.05 ? 138 TRP A C   1 
ATOM   639  O  O   . TRP A 1 138 ? 127.610 135.554 109.023 1.00 112.64 ? 138 TRP A O   1 
ATOM   640  C  CB  . TRP A 1 138 ? 130.190 136.058 108.146 1.00 106.94 ? 138 TRP A CB  1 
ATOM   641  C  CG  . TRP A 1 138 ? 131.613 136.032 107.700 1.00 104.77 ? 138 TRP A CG  1 
ATOM   642  C  CD1 . TRP A 1 138 ? 132.141 136.657 106.612 1.00 103.59 ? 138 TRP A CD1 1 
ATOM   643  C  CD2 . TRP A 1 138 ? 132.694 135.344 108.332 1.00 101.22 ? 138 TRP A CD2 1 
ATOM   644  N  NE1 . TRP A 1 138 ? 133.486 136.400 106.525 1.00 99.54  ? 138 TRP A NE1 1 
ATOM   645  C  CE2 . TRP A 1 138 ? 133.850 135.596 107.572 1.00 101.85 ? 138 TRP A CE2 1 
ATOM   646  C  CE3 . TRP A 1 138 ? 132.798 134.540 109.469 1.00 99.74  ? 138 TRP A CE3 1 
ATOM   647  C  CZ2 . TRP A 1 138 ? 135.091 135.074 107.909 1.00 106.24 ? 138 TRP A CZ2 1 
ATOM   648  C  CZ3 . TRP A 1 138 ? 134.030 134.023 109.802 1.00 104.46 ? 138 TRP A CZ3 1 
ATOM   649  C  CH2 . TRP A 1 138 ? 135.161 134.291 109.026 1.00 108.36 ? 138 TRP A CH2 1 
ATOM   650  N  N   . HIS A 1 139 ? 126.897 134.861 107.009 1.00 94.86  ? 139 HIS A N   1 
ATOM   651  C  CA  . HIS A 1 139 ? 125.493 135.014 107.362 1.00 95.87  ? 139 HIS A CA  1 
ATOM   652  C  C   . HIS A 1 139 ? 125.026 133.977 108.373 1.00 104.88 ? 139 HIS A C   1 
ATOM   653  O  O   . HIS A 1 139 ? 124.063 134.233 109.100 1.00 110.55 ? 139 HIS A O   1 
ATOM   654  C  CB  . HIS A 1 139 ? 124.636 134.942 106.103 1.00 95.16  ? 139 HIS A CB  1 
ATOM   655  C  CG  . HIS A 1 139 ? 125.085 135.871 105.021 1.00 100.22 ? 139 HIS A CG  1 
ATOM   656  N  ND1 . HIS A 1 139 ? 125.889 135.465 103.979 1.00 101.88 ? 139 HIS A ND1 1 
ATOM   657  C  CD2 . HIS A 1 139 ? 124.849 137.189 104.824 1.00 104.96 ? 139 HIS A CD2 1 
ATOM   658  C  CE1 . HIS A 1 139 ? 126.126 136.492 103.184 1.00 109.34 ? 139 HIS A CE1 1 
ATOM   659  N  NE2 . HIS A 1 139 ? 125.506 137.550 103.674 1.00 111.54 ? 139 HIS A NE2 1 
ATOM   660  N  N   . ARG A 1 140 ? 125.683 132.820 108.438 1.00 99.43  ? 140 ARG A N   1 
ATOM   661  C  CA  . ARG A 1 140 ? 125.319 131.794 109.405 1.00 87.73  ? 140 ARG A CA  1 
ATOM   662  C  C   . ARG A 1 140 ? 125.621 132.209 110.839 1.00 94.04  ? 140 ARG A C   1 
ATOM   663  O  O   . ARG A 1 140 ? 125.166 131.537 111.775 1.00 101.60 ? 140 ARG A O   1 
ATOM   664  C  CB  . ARG A 1 140 ? 126.047 130.494 109.064 1.00 93.74  ? 140 ARG A CB  1 
ATOM   665  C  CG  . ARG A 1 140 ? 125.359 129.236 109.548 1.00 103.56 ? 140 ARG A CG  1 
ATOM   666  C  CD  . ARG A 1 140 ? 123.925 129.157 109.078 1.00 101.07 ? 140 ARG A CD  1 
ATOM   667  N  NE  . ARG A 1 140 ? 123.800 128.560 107.755 1.00 99.79  ? 140 ARG A NE  1 
ATOM   668  C  CZ  . ARG A 1 140 ? 123.670 127.261 107.530 1.00 97.18  ? 140 ARG A CZ  1 
ATOM   669  N  NH1 . ARG A 1 140 ? 123.684 126.385 108.518 1.00 103.15 ? 140 ARG A NH1 1 
ATOM   670  N  NH2 . ARG A 1 140 ? 123.519 126.830 106.283 1.00 100.36 ? 140 ARG A NH2 1 
ATOM   671  N  N   . SER A 1 141 ? 126.373 133.295 111.028 1.00 104.80 ? 141 SER A N   1 
ATOM   672  C  CA  . SER A 1 141 ? 126.680 133.765 112.372 1.00 104.30 ? 141 SER A CA  1 
ATOM   673  C  C   . SER A 1 141 ? 125.425 134.182 113.120 1.00 103.70 ? 141 SER A C   1 
ATOM   674  O  O   . SER A 1 141 ? 125.352 134.016 114.339 1.00 106.66 ? 141 SER A O   1 
ATOM   675  C  CB  . SER A 1 141 ? 127.667 134.928 112.306 1.00 102.18 ? 141 SER A CB  1 
ATOM   676  O  OG  . SER A 1 141 ? 127.132 136.000 111.553 1.00 108.84 ? 141 SER A OG  1 
ATOM   677  N  N   . GLU A 1 142 ? 124.431 134.721 112.415 1.00 108.56 ? 142 GLU A N   1 
ATOM   678  C  CA  . GLU A 1 142 ? 123.187 135.112 113.070 1.00 109.13 ? 142 GLU A CA  1 
ATOM   679  C  C   . GLU A 1 142 ? 122.459 133.897 113.634 1.00 109.11 ? 142 GLU A C   1 
ATOM   680  O  O   . GLU A 1 142 ? 121.993 133.909 114.782 1.00 110.94 ? 142 GLU A O   1 
ATOM   681  C  CB  . GLU A 1 142 ? 122.307 135.874 112.081 1.00 109.42 ? 142 GLU A CB  1 
ATOM   682  C  CG  . GLU A 1 142 ? 120.821 135.651 112.249 1.00 119.86 ? 142 GLU A CG  1 
ATOM   683  C  CD  . GLU A 1 142 ? 120.009 136.427 111.235 1.00 126.22 ? 142 GLU A CD  1 
ATOM   684  O  OE1 . GLU A 1 142 ? 120.605 137.227 110.484 1.00 120.35 ? 142 GLU A OE1 1 
ATOM   685  O  OE2 . GLU A 1 142 ? 118.776 136.237 111.185 1.00 124.21 ? 142 GLU A OE2 1 
ATOM   686  N  N   . THR A 1 143 ? 122.366 132.827 112.843 1.00 107.37 ? 143 THR A N   1 
ATOM   687  C  CA  . THR A 1 143 ? 121.739 131.601 113.323 1.00 102.68 ? 143 THR A CA  1 
ATOM   688  C  C   . THR A 1 143 ? 122.523 130.998 114.479 1.00 104.37 ? 143 THR A C   1 
ATOM   689  O  O   . THR A 1 143 ? 121.937 130.524 115.460 1.00 113.02 ? 143 THR A O   1 
ATOM   690  C  CB  . THR A 1 143 ? 121.616 130.596 112.180 1.00 103.16 ? 143 THR A CB  1 
ATOM   691  O  OG1 . THR A 1 143 ? 121.180 131.273 110.996 1.00 112.15 ? 143 THR A OG1 1 
ATOM   692  C  CG2 . THR A 1 143 ? 120.618 129.513 112.532 1.00 106.85 ? 143 THR A CG2 1 
ATOM   693  N  N   . LEU A 1 144 ? 123.853 131.007 114.381 1.00 109.30 ? 144 LEU A N   1 
ATOM   694  C  CA  . LEU A 1 144 ? 124.664 130.458 115.462 1.00 111.67 ? 144 LEU A CA  1 
ATOM   695  C  C   . LEU A 1 144 ? 124.497 131.268 116.742 1.00 111.29 ? 144 LEU A C   1 
ATOM   696  O  O   . LEU A 1 144 ? 124.446 130.702 117.840 1.00 113.96 ? 144 LEU A O   1 
ATOM   697  C  CB  . LEU A 1 144 ? 126.129 130.399 115.039 1.00 111.29 ? 144 LEU A CB  1 
ATOM   698  C  CG  . LEU A 1 144 ? 126.486 129.273 114.066 1.00 109.89 ? 144 LEU A CG  1 
ATOM   699  C  CD1 . LEU A 1 144 ? 127.925 128.850 114.255 1.00 114.89 ? 144 LEU A CD1 1 
ATOM   700  C  CD2 . LEU A 1 144 ? 125.561 128.085 114.241 1.00 108.38 ? 144 LEU A CD2 1 
ATOM   701  N  N   . GLY A 1 145 ? 124.401 132.592 116.624 1.00 101.86 ? 145 GLY A N   1 
ATOM   702  C  CA  . GLY A 1 145 ? 124.171 133.416 117.797 1.00 100.82 ? 145 GLY A CA  1 
ATOM   703  C  C   . GLY A 1 145 ? 122.808 133.181 118.418 1.00 108.22 ? 145 GLY A C   1 
ATOM   704  O  O   . GLY A 1 145 ? 122.670 133.166 119.645 1.00 112.74 ? 145 GLY A O   1 
ATOM   705  N  N   . ALA A 1 146 ? 121.782 132.999 117.584 1.00 108.14 ? 146 ALA A N   1 
ATOM   706  C  CA  . ALA A 1 146 ? 120.463 132.667 118.115 1.00 107.61 ? 146 ALA A CA  1 
ATOM   707  C  C   . ALA A 1 146 ? 120.493 131.342 118.866 1.00 106.97 ? 146 ALA A C   1 
ATOM   708  O  O   . ALA A 1 146 ? 119.921 131.219 119.959 1.00 107.64 ? 146 ALA A O   1 
ATOM   709  C  CB  . ALA A 1 146 ? 119.438 132.621 116.985 1.00 102.07 ? 146 ALA A CB  1 
ATOM   710  N  N   . LEU A 1 147 ? 121.170 130.341 118.300 1.00 96.20  ? 147 LEU A N   1 
ATOM   711  C  CA  . LEU A 1 147 ? 121.291 129.056 118.980 1.00 93.10  ? 147 LEU A CA  1 
ATOM   712  C  C   . LEU A 1 147 ? 122.041 129.198 120.297 1.00 99.28  ? 147 LEU A C   1 
ATOM   713  O  O   . LEU A 1 147 ? 121.668 128.582 121.303 1.00 108.38 ? 147 LEU A O   1 
ATOM   714  C  CB  . LEU A 1 147 ? 121.991 128.047 118.073 1.00 98.58  ? 147 LEU A CB  1 
ATOM   715  C  CG  . LEU A 1 147 ? 122.209 126.658 118.669 1.00 101.43 ? 147 LEU A CG  1 
ATOM   716  C  CD1 . LEU A 1 147 ? 120.895 125.912 118.766 1.00 100.30 ? 147 LEU A CD1 1 
ATOM   717  C  CD2 . LEU A 1 147 ? 123.210 125.877 117.844 1.00 101.58 ? 147 LEU A CD2 1 
ATOM   718  N  N   . ALA A 1 148 ? 123.107 130.001 120.308 1.00 98.36  ? 148 ALA A N   1 
ATOM   719  C  CA  . ALA A 1 148 ? 123.865 130.211 121.536 1.00 102.96 ? 148 ALA A CA  1 
ATOM   720  C  C   . ALA A 1 148 ? 123.012 130.877 122.605 1.00 106.27 ? 148 ALA A C   1 
ATOM   721  O  O   . ALA A 1 148 ? 123.075 130.506 123.783 1.00 111.82 ? 148 ALA A O   1 
ATOM   722  C  CB  . ALA A 1 148 ? 125.110 131.047 121.246 1.00 101.50 ? 148 ALA A CB  1 
ATOM   723  N  N   . SER A 1 149 ? 122.210 131.869 122.214 1.00 104.02 ? 149 SER A N   1 
ATOM   724  C  CA  . SER A 1 149 ? 121.331 132.524 123.176 1.00 107.20 ? 149 SER A CA  1 
ATOM   725  C  C   . SER A 1 149 ? 120.310 131.546 123.741 1.00 112.37 ? 149 SER A C   1 
ATOM   726  O  O   . SER A 1 149 ? 120.044 131.542 124.950 1.00 116.78 ? 149 SER A O   1 
ATOM   727  C  CB  . SER A 1 149 ? 120.631 133.714 122.523 1.00 106.18 ? 149 SER A CB  1 
ATOM   728  O  OG  . SER A 1 149 ? 119.544 133.284 121.726 1.00 115.77 ? 149 SER A OG  1 
ATOM   729  N  N   . VAL A 1 150 ? 119.736 130.700 122.883 1.00 113.17 ? 150 VAL A N   1 
ATOM   730  C  CA  . VAL A 1 150 ? 118.771 129.709 123.358 1.00 108.17 ? 150 VAL A CA  1 
ATOM   731  C  C   . VAL A 1 150 ? 119.431 128.747 124.339 1.00 108.70 ? 150 VAL A C   1 
ATOM   732  O  O   . VAL A 1 150 ? 118.863 128.414 125.388 1.00 116.20 ? 150 VAL A O   1 
ATOM   733  C  CB  . VAL A 1 150 ? 118.142 128.965 122.166 1.00 106.86 ? 150 VAL A CB  1 
ATOM   734  C  CG1 . VAL A 1 150 ? 117.603 127.615 122.602 1.00 107.15 ? 150 VAL A CG1 1 
ATOM   735  C  CG2 . VAL A 1 150 ? 117.042 129.803 121.544 1.00 104.18 ? 150 VAL A CG2 1 
ATOM   736  N  N   . VAL A 1 151 ? 120.643 128.290 124.019 1.00 105.98 ? 151 VAL A N   1 
ATOM   737  C  CA  . VAL A 1 151 ? 121.338 127.345 124.889 1.00 107.35 ? 151 VAL A CA  1 
ATOM   738  C  C   . VAL A 1 151 ? 121.656 127.984 126.235 1.00 112.87 ? 151 VAL A C   1 
ATOM   739  O  O   . VAL A 1 151 ? 121.501 127.355 127.289 1.00 120.07 ? 151 VAL A O   1 
ATOM   740  C  CB  . VAL A 1 151 ? 122.607 126.819 124.194 1.00 113.61 ? 151 VAL A CB  1 
ATOM   741  C  CG1 . VAL A 1 151 ? 123.530 126.152 125.196 1.00 114.00 ? 151 VAL A CG1 1 
ATOM   742  C  CG2 . VAL A 1 151 ? 122.233 125.850 123.091 1.00 113.38 ? 151 VAL A CG2 1 
ATOM   743  N  N   . SER A 1 152 ? 122.114 129.238 126.225 1.00 109.39 ? 152 SER A N   1 
ATOM   744  C  CA  . SER A 1 152 ? 122.411 129.923 127.479 1.00 109.13 ? 152 SER A CA  1 
ATOM   745  C  C   . SER A 1 152 ? 121.154 130.102 128.321 1.00 111.13 ? 152 SER A C   1 
ATOM   746  O  O   . SER A 1 152 ? 121.187 129.942 129.550 1.00 118.91 ? 152 SER A O   1 
ATOM   747  C  CB  . SER A 1 152 ? 123.062 131.274 127.196 1.00 110.52 ? 152 SER A CB  1 
ATOM   748  O  OG  . SER A 1 152 ? 122.081 132.257 126.923 1.00 114.77 ? 152 SER A OG  1 
ATOM   749  N  N   . LEU A 1 153 ? 120.036 130.444 127.676 1.00 110.65 ? 153 LEU A N   1 
ATOM   750  C  CA  . LEU A 1 153 ? 118.778 130.555 128.403 1.00 113.61 ? 153 LEU A CA  1 
ATOM   751  C  C   . LEU A 1 153 ? 118.396 129.225 129.034 1.00 116.96 ? 153 LEU A C   1 
ATOM   752  O  O   . LEU A 1 153 ? 117.955 129.183 130.187 1.00 116.12 ? 153 LEU A O   1 
ATOM   753  C  CB  . LEU A 1 153 ? 117.672 131.042 127.471 1.00 117.30 ? 153 LEU A CB  1 
ATOM   754  C  CG  . LEU A 1 153 ? 116.252 130.951 128.025 1.00 116.11 ? 153 LEU A CG  1 
ATOM   755  C  CD1 . LEU A 1 153 ? 116.076 131.899 129.195 1.00 114.56 ? 153 LEU A CD1 1 
ATOM   756  C  CD2 . LEU A 1 153 ? 115.239 131.247 126.939 1.00 113.35 ? 153 LEU A CD2 1 
ATOM   757  N  N   . TRP A 1 154 ? 118.564 128.127 128.294 1.00 125.87 ? 154 TRP A N   1 
ATOM   758  C  CA  . TRP A 1 154 ? 118.271 126.811 128.853 1.00 120.21 ? 154 TRP A CA  1 
ATOM   759  C  C   . TRP A 1 154 ? 119.165 126.509 130.048 1.00 121.92 ? 154 TRP A C   1 
ATOM   760  O  O   . TRP A 1 154 ? 118.702 125.965 131.055 1.00 125.07 ? 154 TRP A O   1 
ATOM   761  C  CB  . TRP A 1 154 ? 118.431 125.732 127.785 1.00 116.97 ? 154 TRP A CB  1 
ATOM   762  C  CG  . TRP A 1 154 ? 117.190 125.473 126.997 1.00 118.08 ? 154 TRP A CG  1 
ATOM   763  C  CD1 . TRP A 1 154 ? 116.684 126.243 125.997 1.00 122.05 ? 154 TRP A CD1 1 
ATOM   764  C  CD2 . TRP A 1 154 ? 116.293 124.366 127.146 1.00 131.83 ? 154 TRP A CD2 1 
ATOM   765  N  NE1 . TRP A 1 154 ? 115.530 125.685 125.507 1.00 123.92 ? 154 TRP A NE1 1 
ATOM   766  C  CE2 . TRP A 1 154 ? 115.267 124.532 126.197 1.00 131.17 ? 154 TRP A CE2 1 
ATOM   767  C  CE3 . TRP A 1 154 ? 116.258 123.251 127.988 1.00 132.42 ? 154 TRP A CE3 1 
ATOM   768  C  CZ2 . TRP A 1 154 ? 114.216 123.627 126.067 1.00 127.81 ? 154 TRP A CZ2 1 
ATOM   769  C  CZ3 . TRP A 1 154 ? 115.215 122.352 127.858 1.00 124.83 ? 154 TRP A CZ3 1 
ATOM   770  C  CH2 . TRP A 1 154 ? 114.208 122.546 126.905 1.00 125.04 ? 154 TRP A CH2 1 
ATOM   771  N  N   . MET A 1 155 ? 120.450 126.857 129.953 1.00 125.86 ? 155 MET A N   1 
ATOM   772  C  CA  . MET A 1 155 ? 121.373 126.630 131.063 1.00 122.21 ? 155 MET A CA  1 
ATOM   773  C  C   . MET A 1 155 ? 120.913 127.354 132.321 1.00 125.15 ? 155 MET A C   1 
ATOM   774  O  O   . MET A 1 155 ? 120.783 126.751 133.397 1.00 130.24 ? 155 MET A O   1 
ATOM   775  C  CB  . MET A 1 155 ? 122.773 127.108 130.678 1.00 124.14 ? 155 MET A CB  1 
ATOM   776  C  CG  . MET A 1 155 ? 123.477 126.282 129.628 1.00 131.13 ? 155 MET A CG  1 
ATOM   777  S  SD  . MET A 1 155 ? 125.245 126.181 129.961 1.00 148.71 ? 155 MET A SD  1 
ATOM   778  C  CE  . MET A 1 155 ? 125.911 126.201 128.299 1.00 127.92 ? 155 MET A CE  1 
ATOM   779  N  N   . VAL A 1 156 ? 120.663 128.659 132.200 1.00 112.83 ? 156 VAL A N   1 
ATOM   780  C  CA  . VAL A 1 156 ? 120.298 129.445 133.374 1.00 112.84 ? 156 VAL A CA  1 
ATOM   781  C  C   . VAL A 1 156 ? 118.950 128.994 133.922 1.00 116.89 ? 156 VAL A C   1 
ATOM   782  O  O   . VAL A 1 156 ? 118.755 128.918 135.142 1.00 117.08 ? 156 VAL A O   1 
ATOM   783  C  CB  . VAL A 1 156 ? 120.305 130.946 133.038 1.00 111.99 ? 156 VAL A CB  1 
ATOM   784  C  CG1 . VAL A 1 156 ? 120.079 131.761 134.292 1.00 113.34 ? 156 VAL A CG1 1 
ATOM   785  C  CG2 . VAL A 1 156 ? 121.621 131.331 132.397 1.00 113.23 ? 156 VAL A CG2 1 
ATOM   786  N  N   . THR A 1 157 ? 118.002 128.683 133.036 1.00 119.11 ? 157 THR A N   1 
ATOM   787  C  CA  . THR A 1 157 ? 116.696 128.218 133.483 1.00 117.19 ? 157 THR A CA  1 
ATOM   788  C  C   . THR A 1 157 ? 116.807 126.894 134.224 1.00 120.02 ? 157 THR A C   1 
ATOM   789  O  O   . THR A 1 157 ? 116.133 126.687 135.236 1.00 124.61 ? 157 THR A O   1 
ATOM   790  C  CB  . THR A 1 157 ? 115.752 128.095 132.288 1.00 122.90 ? 157 THR A CB  1 
ATOM   791  O  OG1 . THR A 1 157 ? 115.390 129.404 131.834 1.00 124.44 ? 157 THR A OG1 1 
ATOM   792  C  CG2 . THR A 1 157 ? 114.497 127.338 132.671 1.00 123.92 ? 157 THR A CG2 1 
ATOM   793  N  N   . GLY A 1 158 ? 117.651 125.983 133.739 1.00 119.45 ? 158 GLY A N   1 
ATOM   794  C  CA  . GLY A 1 158 ? 117.840 124.725 134.439 1.00 115.19 ? 158 GLY A CA  1 
ATOM   795  C  C   . GLY A 1 158 ? 118.460 124.912 135.809 1.00 113.45 ? 158 GLY A C   1 
ATOM   796  O  O   . GLY A 1 158 ? 118.051 124.267 136.779 1.00 116.77 ? 158 GLY A O   1 
ATOM   797  N  N   . ILE A 1 159 ? 119.450 125.801 135.910 1.00 106.59 ? 159 ILE A N   1 
ATOM   798  C  CA  . ILE A 1 159 ? 120.058 126.073 137.212 1.00 104.67 ? 159 ILE A CA  1 
ATOM   799  C  C   . ILE A 1 159 ? 119.015 126.631 138.175 1.00 111.59 ? 159 ILE A C   1 
ATOM   800  O  O   . ILE A 1 159 ? 118.915 126.203 139.334 1.00 119.67 ? 159 ILE A O   1 
ATOM   801  C  CB  . ILE A 1 159 ? 121.255 127.027 137.056 1.00 107.99 ? 159 ILE A CB  1 
ATOM   802  C  CG1 . ILE A 1 159 ? 122.531 126.236 136.775 1.00 112.58 ? 159 ILE A CG1 1 
ATOM   803  C  CG2 . ILE A 1 159 ? 121.440 127.866 138.306 1.00 107.21 ? 159 ILE A CG2 1 
ATOM   804  C  CD1 . ILE A 1 159 ? 123.621 127.058 136.134 1.00 112.30 ? 159 ILE A CD1 1 
ATOM   805  N  N   . LEU A 1 160 ? 118.208 127.584 137.700 1.00 118.15 ? 160 LEU A N   1 
ATOM   806  C  CA  . LEU A 1 160 ? 117.182 128.176 138.551 1.00 115.56 ? 160 LEU A CA  1 
ATOM   807  C  C   . LEU A 1 160 ? 116.132 127.150 138.954 1.00 114.62 ? 160 LEU A C   1 
ATOM   808  O  O   . LEU A 1 160 ? 115.654 127.156 140.093 1.00 116.22 ? 160 LEU A O   1 
ATOM   809  C  CB  . LEU A 1 160 ? 116.527 129.355 137.838 1.00 113.85 ? 160 LEU A CB  1 
ATOM   810  C  CG  . LEU A 1 160 ? 117.388 130.611 137.732 1.00 111.59 ? 160 LEU A CG  1 
ATOM   811  C  CD1 . LEU A 1 160 ? 116.636 131.707 137.007 1.00 115.50 ? 160 LEU A CD1 1 
ATOM   812  C  CD2 . LEU A 1 160 ? 117.817 131.068 139.110 1.00 112.57 ? 160 LEU A CD2 1 
ATOM   813  N  N   . LEU A 1 161 ? 115.748 126.271 138.027 1.00 114.91 ? 161 LEU A N   1 
ATOM   814  C  CA  . LEU A 1 161 ? 114.761 125.245 138.339 1.00 113.09 ? 161 LEU A CA  1 
ATOM   815  C  C   . LEU A 1 161 ? 115.288 124.275 139.384 1.00 118.58 ? 161 LEU A C   1 
ATOM   816  O  O   . LEU A 1 161 ? 114.555 123.876 140.295 1.00 124.54 ? 161 LEU A O   1 
ATOM   817  C  CB  . LEU A 1 161 ? 114.362 124.499 137.069 1.00 113.81 ? 161 LEU A CB  1 
ATOM   818  C  CG  . LEU A 1 161 ? 113.223 125.128 136.271 1.00 116.76 ? 161 LEU A CG  1 
ATOM   819  C  CD1 . LEU A 1 161 ? 112.861 124.257 135.085 1.00 120.42 ? 161 LEU A CD1 1 
ATOM   820  C  CD2 . LEU A 1 161 ? 112.020 125.344 137.164 1.00 118.86 ? 161 LEU A CD2 1 
ATOM   821  N  N   . TYR A 1 162 ? 116.558 123.880 139.270 1.00 119.64 ? 162 TYR A N   1 
ATOM   822  C  CA  . TYR A 1 162 ? 117.137 123.015 140.290 1.00 121.50 ? 162 TYR A CA  1 
ATOM   823  C  C   . TYR A 1 162 ? 117.163 123.710 141.643 1.00 123.38 ? 162 TYR A C   1 
ATOM   824  O  O   . TYR A 1 162 ? 116.851 123.095 142.671 1.00 130.94 ? 162 TYR A O   1 
ATOM   825  C  CB  . TYR A 1 162 ? 118.545 122.579 139.892 1.00 120.47 ? 162 TYR A CB  1 
ATOM   826  C  CG  . TYR A 1 162 ? 119.353 122.066 141.060 1.00 124.11 ? 162 TYR A CG  1 
ATOM   827  C  CD1 . TYR A 1 162 ? 119.204 120.762 141.508 1.00 122.39 ? 162 TYR A CD1 1 
ATOM   828  C  CD2 . TYR A 1 162 ? 120.266 122.882 141.715 1.00 122.08 ? 162 TYR A CD2 1 
ATOM   829  C  CE1 . TYR A 1 162 ? 119.934 120.287 142.576 1.00 123.13 ? 162 TYR A CE1 1 
ATOM   830  C  CE2 . TYR A 1 162 ? 121.000 122.415 142.784 1.00 125.78 ? 162 TYR A CE2 1 
ATOM   831  C  CZ  . TYR A 1 162 ? 120.830 121.117 143.210 1.00 127.22 ? 162 TYR A CZ  1 
ATOM   832  O  OH  . TYR A 1 162 ? 121.562 120.647 144.274 1.00 125.27 ? 162 TYR A OH  1 
ATOM   833  N  N   . LEU A 1 163 ? 117.538 124.990 141.666 1.00 113.46 ? 163 LEU A N   1 
ATOM   834  C  CA  . LEU A 1 163 ? 117.562 125.718 142.930 1.00 113.80 ? 163 LEU A CA  1 
ATOM   835  C  C   . LEU A 1 163 ? 116.170 125.801 143.544 1.00 118.44 ? 163 LEU A C   1 
ATOM   836  O  O   . LEU A 1 163 ? 116.005 125.615 144.755 1.00 118.89 ? 163 LEU A O   1 
ATOM   837  C  CB  . LEU A 1 163 ? 118.142 127.115 142.722 1.00 119.60 ? 163 LEU A CB  1 
ATOM   838  C  CG  . LEU A 1 163 ? 119.665 127.199 142.635 1.00 122.62 ? 163 LEU A CG  1 
ATOM   839  C  CD1 . LEU A 1 163 ? 120.120 128.646 142.668 1.00 121.76 ? 163 LEU A CD1 1 
ATOM   840  C  CD2 . LEU A 1 163 ? 120.305 126.411 143.760 1.00 118.13 ? 163 LEU A CD2 1 
ATOM   841  N  N   . ALA A 1 164 ? 115.154 126.073 142.723 1.00 123.23 ? 164 ALA A N   1 
ATOM   842  C  CA  . ALA A 1 164 ? 113.788 126.147 143.231 1.00 118.34 ? 164 ALA A CA  1 
ATOM   843  C  C   . ALA A 1 164 ? 113.316 124.798 143.753 1.00 123.28 ? 164 ALA A C   1 
ATOM   844  O  O   . ALA A 1 164 ? 112.642 124.725 144.787 1.00 128.09 ? 164 ALA A O   1 
ATOM   845  C  CB  . ALA A 1 164 ? 112.850 126.655 142.139 1.00 119.02 ? 164 ALA A CB  1 
ATOM   846  N  N   . PHE A 1 165 ? 113.650 123.717 143.045 1.00 133.22 ? 165 PHE A N   1 
ATOM   847  C  CA  . PHE A 1 165 ? 113.260 122.387 143.501 1.00 129.86 ? 165 PHE A CA  1 
ATOM   848  C  C   . PHE A 1 165 ? 113.923 122.045 144.828 1.00 130.34 ? 165 PHE A C   1 
ATOM   849  O  O   . PHE A 1 165 ? 113.289 121.465 145.716 1.00 129.45 ? 165 PHE A O   1 
ATOM   850  C  CB  . PHE A 1 165 ? 113.614 121.348 142.441 1.00 129.59 ? 165 PHE A CB  1 
ATOM   851  C  CG  . PHE A 1 165 ? 113.013 120.000 142.693 1.00 136.13 ? 165 PHE A CG  1 
ATOM   852  C  CD1 . PHE A 1 165 ? 111.678 119.763 142.422 1.00 134.52 ? 165 PHE A CD1 1 
ATOM   853  C  CD2 . PHE A 1 165 ? 113.785 118.968 143.197 1.00 135.35 ? 165 PHE A CD2 1 
ATOM   854  C  CE1 . PHE A 1 165 ? 111.123 118.521 142.653 1.00 134.26 ? 165 PHE A CE1 1 
ATOM   855  C  CE2 . PHE A 1 165 ? 113.236 117.725 143.429 1.00 134.38 ? 165 PHE A CE2 1 
ATOM   856  C  CZ  . PHE A 1 165 ? 111.903 117.501 143.156 1.00 134.91 ? 165 PHE A CZ  1 
ATOM   857  N  N   . VAL A 1 166 ? 115.200 122.398 144.981 1.00 126.07 ? 166 VAL A N   1 
ATOM   858  C  CA  . VAL A 1 166 ? 115.882 122.183 146.254 1.00 121.51 ? 166 VAL A CA  1 
ATOM   859  C  C   . VAL A 1 166 ? 115.239 123.028 147.347 1.00 122.77 ? 166 VAL A C   1 
ATOM   860  O  O   . VAL A 1 166 ? 115.130 122.600 148.501 1.00 124.03 ? 166 VAL A O   1 
ATOM   861  C  CB  . VAL A 1 166 ? 117.386 122.480 146.106 1.00 123.22 ? 166 VAL A CB  1 
ATOM   862  C  CG1 . VAL A 1 166 ? 117.992 122.905 147.432 1.00 119.89 ? 166 VAL A CG1 1 
ATOM   863  C  CG2 . VAL A 1 166 ? 118.108 121.264 145.560 1.00 123.81 ? 166 VAL A CG2 1 
ATOM   864  N  N   . ARG A 1 167 ? 114.802 124.239 147.003 1.00 126.99 ? 167 ARG A N   1 
ATOM   865  C  CA  . ARG A 1 167 ? 114.131 125.087 147.982 1.00 124.07 ? 167 ARG A CA  1 
ATOM   866  C  C   . ARG A 1 167 ? 112.807 124.482 148.432 1.00 125.70 ? 167 ARG A C   1 
ATOM   867  O  O   . ARG A 1 167 ? 112.450 124.568 149.611 1.00 127.03 ? 167 ARG A O   1 
ATOM   868  C  CB  . ARG A 1 167 ? 113.905 126.481 147.402 1.00 125.82 ? 167 ARG A CB  1 
ATOM   869  C  CG  . ARG A 1 167 ? 115.039 127.452 147.653 1.00 125.85 ? 167 ARG A CG  1 
ATOM   870  C  CD  . ARG A 1 167 ? 114.597 128.879 147.398 1.00 126.25 ? 167 ARG A CD  1 
ATOM   871  N  NE  . ARG A 1 167 ? 115.652 129.838 147.697 1.00 125.40 ? 167 ARG A NE  1 
ATOM   872  C  CZ  . ARG A 1 167 ? 115.477 131.151 147.740 1.00 127.73 ? 167 ARG A CZ  1 
ATOM   873  N  NH1 . ARG A 1 167 ? 114.296 131.698 147.508 1.00 127.25 ? 167 ARG A NH1 1 
ATOM   874  N  NH2 . ARG A 1 167 ? 116.513 131.935 148.021 1.00 128.76 ? 167 ARG A NH2 1 
ATOM   875  N  N   . LEU A 1 168 ? 112.062 123.876 147.506 1.00 130.14 ? 168 LEU A N   1 
ATOM   876  C  CA  . LEU A 1 168 ? 110.718 123.406 147.828 1.00 132.52 ? 168 LEU A CA  1 
ATOM   877  C  C   . LEU A 1 168 ? 110.740 122.286 148.863 1.00 137.12 ? 168 LEU A C   1 
ATOM   878  O  O   . LEU A 1 168 ? 109.913 122.270 149.782 1.00 138.70 ? 168 LEU A O   1 
ATOM   879  C  CB  . LEU A 1 168 ? 110.006 122.952 146.556 1.00 134.76 ? 168 LEU A CB  1 
ATOM   880  C  CG  . LEU A 1 168 ? 109.189 124.036 145.852 1.00 133.14 ? 168 LEU A CG  1 
ATOM   881  C  CD1 . LEU A 1 168 ? 108.344 123.443 144.740 1.00 131.95 ? 168 LEU A CD1 1 
ATOM   882  C  CD2 . LEU A 1 168 ? 108.317 124.775 146.849 1.00 131.46 ? 168 LEU A CD2 1 
ATOM   883  N  N   . LEU A 1 169 ? 111.668 121.343 148.733 1.00 140.11 ? 169 LEU A N   1 
ATOM   884  C  CA  . LEU A 1 169 ? 111.784 120.211 149.644 1.00 136.37 ? 169 LEU A CA  1 
ATOM   885  C  C   . LEU A 1 169 ? 113.110 120.293 150.392 1.00 140.92 ? 169 LEU A C   1 
ATOM   886  O  O   . LEU A 1 169 ? 114.159 120.510 149.780 1.00 141.68 ? 169 LEU A O   1 
ATOM   887  C  CB  . LEU A 1 169 ? 111.609 118.894 148.876 1.00 134.88 ? 169 LEU A CB  1 
ATOM   888  C  CG  . LEU A 1 169 ? 112.531 118.494 147.721 1.00 137.87 ? 169 LEU A CG  1 
ATOM   889  C  CD1 . LEU A 1 169 ? 113.786 117.795 148.172 1.00 136.09 ? 169 LEU A CD1 1 
ATOM   890  C  CD2 . LEU A 1 169 ? 111.761 117.622 146.741 1.00 138.24 ? 169 LEU A CD2 1 
ATOM   891  N  N   . HIS A 1 170 ? 113.053 120.094 151.711 1.00 148.72 ? 170 HIS A N   1 
ATOM   892  C  CA  . HIS A 1 170 ? 113.989 120.691 152.669 1.00 147.65 ? 170 HIS A CA  1 
ATOM   893  C  C   . HIS A 1 170 ? 113.974 122.217 152.538 1.00 145.84 ? 170 HIS A C   1 
ATOM   894  O  O   . HIS A 1 170 ? 114.955 122.861 152.164 1.00 146.18 ? 170 HIS A O   1 
ATOM   895  C  CB  . HIS A 1 170 ? 115.424 120.154 152.553 1.00 145.47 ? 170 HIS A CB  1 
ATOM   896  C  CG  . HIS A 1 170 ? 115.534 118.776 151.984 1.00 149.32 ? 170 HIS A CG  1 
ATOM   897  N  ND1 . HIS A 1 170 ? 115.924 118.532 150.684 1.00 149.90 ? 170 HIS A ND1 1 
ATOM   898  C  CD2 . HIS A 1 170 ? 115.332 117.563 152.550 1.00 148.26 ? 170 HIS A CD2 1 
ATOM   899  C  CE1 . HIS A 1 170 ? 115.956 117.227 150.476 1.00 150.88 ? 170 HIS A CE1 1 
ATOM   900  N  NE2 . HIS A 1 170 ? 115.593 116.617 151.589 1.00 150.55 ? 170 HIS A NE2 1 
ATOM   901  N  N   . SER A 1 171 ? 112.811 122.775 152.870 1.00 141.49 ? 171 SER A N   1 
ATOM   902  C  CA  . SER A 1 171 ? 112.564 124.210 152.744 1.00 143.86 ? 171 SER A CA  1 
ATOM   903  C  C   . SER A 1 171 ? 113.345 124.942 153.831 1.00 143.28 ? 171 SER A C   1 
ATOM   904  O  O   . SER A 1 171 ? 112.817 125.332 154.874 1.00 143.13 ? 171 SER A O   1 
ATOM   905  C  CB  . SER A 1 171 ? 111.073 124.502 152.837 1.00 144.90 ? 171 SER A CB  1 
ATOM   906  O  OG  . SER A 1 171 ? 110.372 123.909 151.760 1.00 147.09 ? 171 SER A OG  1 
ATOM   907  N  N   . ASP A 1 172 ? 114.635 125.133 153.570 1.00 143.48 ? 172 ASP A N   1 
ATOM   908  C  CA  . ASP A 1 172 ? 115.539 125.823 154.485 1.00 147.31 ? 172 ASP A CA  1 
ATOM   909  C  C   . ASP A 1 172 ? 116.064 127.054 153.751 1.00 148.89 ? 172 ASP A C   1 
ATOM   910  O  O   . ASP A 1 172 ? 117.083 126.996 153.058 1.00 148.66 ? 172 ASP A O   1 
ATOM   911  C  CB  . ASP A 1 172 ? 116.669 124.896 154.948 1.00 148.01 ? 172 ASP A CB  1 
ATOM   912  C  CG  . ASP A 1 172 ? 117.864 125.653 155.497 1.00 150.79 ? 172 ASP A CG  1 
ATOM   913  O  OD1 . ASP A 1 172 ? 117.661 126.581 156.307 1.00 152.16 ? 172 ASP A OD1 1 
ATOM   914  O  OD2 . ASP A 1 172 ? 119.005 125.321 155.115 1.00 147.57 ? 172 ASP A OD2 1 
ATOM   915  N  N   . TYR A 1 173 ? 115.345 128.165 153.889 1.00 137.06 ? 173 TYR A N   1 
ATOM   916  C  CA  . TYR A 1 173 ? 115.744 129.427 153.286 1.00 132.51 ? 173 TYR A CA  1 
ATOM   917  C  C   . TYR A 1 173 ? 114.912 130.540 153.898 1.00 132.02 ? 173 TYR A C   1 
ATOM   918  O  O   . TYR A 1 173 ? 113.783 130.317 154.340 1.00 136.36 ? 173 TYR A O   1 
ATOM   919  C  CB  . TYR A 1 173 ? 115.572 129.413 151.763 1.00 130.02 ? 173 TYR A CB  1 
ATOM   920  C  CG  . TYR A 1 173 ? 114.163 129.123 151.302 1.00 129.62 ? 173 TYR A CG  1 
ATOM   921  C  CD1 . TYR A 1 173 ? 113.735 127.822 151.095 1.00 130.26 ? 173 TYR A CD1 1 
ATOM   922  C  CD2 . TYR A 1 173 ? 113.263 130.151 151.064 1.00 129.68 ? 173 TYR A CD2 1 
ATOM   923  C  CE1 . TYR A 1 173 ? 112.452 127.553 150.672 1.00 134.72 ? 173 TYR A CE1 1 
ATOM   924  C  CE2 . TYR A 1 173 ? 111.978 129.891 150.642 1.00 128.25 ? 173 TYR A CE2 1 
ATOM   925  C  CZ  . TYR A 1 173 ? 111.579 128.590 150.447 1.00 132.56 ? 173 TYR A CZ  1 
ATOM   926  O  OH  . TYR A 1 173 ? 110.299 128.322 150.026 1.00 132.15 ? 173 TYR A OH  1 
ATOM   927  N  N   . HIS A 1 174 ? 115.482 131.739 153.918 1.00 127.87 ? 174 HIS A N   1 
ATOM   928  C  CA  . HIS A 1 174 ? 114.794 132.927 154.396 1.00 129.98 ? 174 HIS A CA  1 
ATOM   929  C  C   . HIS A 1 174 ? 114.816 133.984 153.304 1.00 132.39 ? 174 HIS A C   1 
ATOM   930  O  O   . HIS A 1 174 ? 115.830 134.170 152.627 1.00 133.49 ? 174 HIS A O   1 
ATOM   931  C  CB  . HIS A 1 174 ? 115.437 133.469 155.675 1.00 131.47 ? 174 HIS A CB  1 
ATOM   932  C  CG  . HIS A 1 174 ? 116.821 134.002 155.479 1.00 134.50 ? 174 HIS A CG  1 
ATOM   933  N  ND1 . HIS A 1 174 ? 117.904 133.186 155.231 1.00 135.64 ? 174 HIS A ND1 1 
ATOM   934  C  CD2 . HIS A 1 174 ? 117.301 135.268 155.498 1.00 135.03 ? 174 HIS A CD2 1 
ATOM   935  C  CE1 . HIS A 1 174 ? 118.990 133.927 155.103 1.00 135.84 ? 174 HIS A CE1 1 
ATOM   936  N  NE2 . HIS A 1 174 ? 118.652 135.194 155.260 1.00 137.83 ? 174 HIS A NE2 1 
ATOM   937  N  N   . ILE A 1 175 ? 113.689 134.665 153.130 1.00 128.81 ? 175 ILE A N   1 
ATOM   938  C  CA  . ILE A 1 175 ? 113.529 135.675 152.093 1.00 127.65 ? 175 ILE A CA  1 
ATOM   939  C  C   . ILE A 1 175 ? 113.237 137.002 152.771 1.00 129.63 ? 175 ILE A C   1 
ATOM   940  O  O   . ILE A 1 175 ? 112.273 137.114 153.538 1.00 128.25 ? 175 ILE A O   1 
ATOM   941  C  CB  . ILE A 1 175 ? 112.412 135.305 151.108 1.00 124.04 ? 175 ILE A CB  1 
ATOM   942  C  CG1 . ILE A 1 175 ? 112.753 133.998 150.395 1.00 125.17 ? 175 ILE A CG1 1 
ATOM   943  C  CG2 . ILE A 1 175 ? 112.192 136.425 150.110 1.00 126.72 ? 175 ILE A CG2 1 
ATOM   944  C  CD1 . ILE A 1 175 ? 111.815 133.659 149.274 1.00 125.43 ? 175 ILE A CD1 1 
ATOM   945  N  N   . GLU A 1 176 ? 114.064 138.004 152.489 1.00 132.54 ? 176 GLU A N   1 
ATOM   946  C  CA  . GLU A 1 176 ? 113.862 139.339 153.039 1.00 131.35 ? 176 GLU A CA  1 
ATOM   947  C  C   . GLU A 1 176 ? 112.709 139.996 152.294 1.00 133.37 ? 176 GLU A C   1 
ATOM   948  O  O   . GLU A 1 176 ? 112.822 140.299 151.103 1.00 138.19 ? 176 GLU A O   1 
ATOM   949  C  CB  . GLU A 1 176 ? 115.140 140.162 152.924 1.00 132.94 ? 176 GLU A CB  1 
ATOM   950  C  CG  . GLU A 1 176 ? 116.408 139.335 152.998 1.00 136.32 ? 176 GLU A CG  1 
ATOM   951  C  CD  . GLU A 1 176 ? 116.838 139.060 154.424 1.00 140.63 ? 176 GLU A CD  1 
ATOM   952  O  OE1 . GLU A 1 176 ? 116.215 139.617 155.351 1.00 139.80 ? 176 GLU A OE1 1 
ATOM   953  O  OE2 . GLU A 1 176 ? 117.800 138.287 154.619 1.00 137.25 ? 176 GLU A OE2 1 
ATOM   954  N  N   . GLY A 1 177 ? 111.594 140.207 152.993 1.00 129.35 ? 177 GLY A N   1 
ATOM   955  C  CA  . GLY A 1 177 ? 110.418 140.752 152.338 1.00 130.54 ? 177 GLY A CA  1 
ATOM   956  C  C   . GLY A 1 177 ? 110.622 142.169 151.841 1.00 132.09 ? 177 GLY A C   1 
ATOM   957  O  O   . GLY A 1 177 ? 110.213 142.510 150.729 1.00 133.46 ? 177 GLY A O   1 
ATOM   958  N  N   . GLY A 1 178 ? 111.256 143.013 152.655 1.00 127.66 ? 178 GLY A N   1 
ATOM   959  C  CA  . GLY A 1 178 ? 111.434 144.402 152.266 1.00 126.16 ? 178 GLY A CA  1 
ATOM   960  C  C   . GLY A 1 178 ? 112.312 144.559 151.040 1.00 125.08 ? 178 GLY A C   1 
ATOM   961  O  O   . GLY A 1 178 ? 111.975 145.294 150.109 1.00 125.67 ? 178 GLY A O   1 
ATOM   962  N  N   . ALA A 1 179 ? 113.449 143.862 151.021 1.00 116.74 ? 179 ALA A N   1 
ATOM   963  C  CA  . ALA A 1 179 ? 114.357 143.967 149.884 1.00 117.31 ? 179 ALA A CA  1 
ATOM   964  C  C   . ALA A 1 179 ? 113.714 143.430 148.613 1.00 120.41 ? 179 ALA A C   1 
ATOM   965  O  O   . ALA A 1 179 ? 113.832 144.038 147.543 1.00 124.53 ? 179 ALA A O   1 
ATOM   966  C  CB  . ALA A 1 179 ? 115.658 143.224 150.180 1.00 116.26 ? 179 ALA A CB  1 
ATOM   967  N  N   . MET A 1 180 ? 113.029 142.290 148.713 1.00 122.03 ? 180 MET A N   1 
ATOM   968  C  CA  . MET A 1 180 ? 112.384 141.707 147.544 1.00 117.88 ? 180 MET A CA  1 
ATOM   969  C  C   . MET A 1 180 ? 111.277 142.610 147.019 1.00 119.72 ? 180 MET A C   1 
ATOM   970  O  O   . MET A 1 180 ? 111.151 142.811 145.805 1.00 120.18 ? 180 MET A O   1 
ATOM   971  C  CB  . MET A 1 180 ? 111.842 140.322 147.893 1.00 118.45 ? 180 MET A CB  1 
ATOM   972  C  CG  . MET A 1 180 ? 110.818 139.781 146.924 1.00 123.38 ? 180 MET A CG  1 
ATOM   973  S  SD  . MET A 1 180 ? 110.693 137.986 146.978 1.00 132.39 ? 180 MET A SD  1 
ATOM   974  C  CE  . MET A 1 180 ? 109.673 137.681 145.541 1.00 123.13 ? 180 MET A CE  1 
ATOM   975  N  N   . LEU A 1 181 ? 110.470 143.174 147.920 1.00 114.51 ? 181 LEU A N   1 
ATOM   976  C  CA  . LEU A 1 181 ? 109.412 144.084 147.499 1.00 113.10 ? 181 LEU A CA  1 
ATOM   977  C  C   . LEU A 1 181 ? 109.986 145.332 146.843 1.00 120.19 ? 181 LEU A C   1 
ATOM   978  O  O   . LEU A 1 181 ? 109.468 145.798 145.820 1.00 124.36 ? 181 LEU A O   1 
ATOM   979  C  CB  . LEU A 1 181 ? 108.538 144.459 148.693 1.00 110.83 ? 181 LEU A CB  1 
ATOM   980  C  CG  . LEU A 1 181 ? 107.379 145.415 148.416 1.00 110.01 ? 181 LEU A CG  1 
ATOM   981  C  CD1 . LEU A 1 181 ? 106.564 144.937 147.233 1.00 110.79 ? 181 LEU A CD1 1 
ATOM   982  C  CD2 . LEU A 1 181 ? 106.503 145.553 149.644 1.00 111.76 ? 181 LEU A CD2 1 
ATOM   983  N  N   . LEU A 1 182 ? 111.053 145.892 147.416 1.00 113.27 ? 182 LEU A N   1 
ATOM   984  C  CA  . LEU A 1 182 ? 111.664 147.077 146.828 1.00 109.87 ? 182 LEU A CA  1 
ATOM   985  C  C   . LEU A 1 182 ? 112.226 146.780 145.446 1.00 109.41 ? 182 LEU A C   1 
ATOM   986  O  O   . LEU A 1 182 ? 112.043 147.569 144.511 1.00 115.08 ? 182 LEU A O   1 
ATOM   987  C  CB  . LEU A 1 182 ? 112.759 147.613 147.746 1.00 111.86 ? 182 LEU A CB  1 
ATOM   988  C  CG  . LEU A 1 182 ? 113.338 148.971 147.355 1.00 114.23 ? 182 LEU A CG  1 
ATOM   989  C  CD1 . LEU A 1 182 ? 112.390 150.085 147.756 1.00 110.46 ? 182 LEU A CD1 1 
ATOM   990  C  CD2 . LEU A 1 182 ? 114.704 149.170 147.985 1.00 113.03 ? 182 LEU A CD2 1 
ATOM   991  N  N   . THR A 1 183 ? 112.909 145.644 145.293 1.00 104.26 ? 183 THR A N   1 
ATOM   992  C  CA  . THR A 1 183 ? 113.460 145.291 143.990 1.00 99.85  ? 183 THR A CA  1 
ATOM   993  C  C   . THR A 1 183 ? 112.356 145.071 142.965 1.00 108.62 ? 183 THR A C   1 
ATOM   994  O  O   . THR A 1 183 ? 112.479 145.496 141.811 1.00 122.14 ? 183 THR A O   1 
ATOM   995  C  CB  . THR A 1 183 ? 114.335 144.047 144.106 1.00 105.57 ? 183 THR A CB  1 
ATOM   996  O  OG1 . THR A 1 183 ? 115.289 144.231 145.156 1.00 109.86 ? 183 THR A OG1 1 
ATOM   997  C  CG2 . THR A 1 183 ? 115.067 143.794 142.804 1.00 105.49 ? 183 THR A CG2 1 
ATOM   998  N  N   . ALA A 1 184 ? 111.268 144.409 143.365 1.00 108.92 ? 184 ALA A N   1 
ATOM   999  C  CA  . ALA A 1 184 ? 110.164 144.180 142.440 1.00 110.97 ? 184 ALA A CA  1 
ATOM   1000 C  C   . ALA A 1 184 ? 109.505 145.490 142.027 1.00 116.97 ? 184 ALA A C   1 
ATOM   1001 O  O   . ALA A 1 184 ? 109.159 145.677 140.854 1.00 121.32 ? 184 ALA A O   1 
ATOM   1002 C  CB  . ALA A 1 184 ? 109.141 143.239 143.069 1.00 117.16 ? 184 ALA A CB  1 
ATOM   1003 N  N   . SER A 1 185 ? 109.315 146.408 142.978 1.00 109.28 ? 185 SER A N   1 
ATOM   1004 C  CA  . SER A 1 185 ? 108.742 147.707 142.643 1.00 110.39 ? 185 SER A CA  1 
ATOM   1005 C  C   . SER A 1 185 ? 109.653 148.482 141.702 1.00 113.57 ? 185 SER A C   1 
ATOM   1006 O  O   . SER A 1 185 ? 109.182 149.118 140.750 1.00 112.61 ? 185 SER A O   1 
ATOM   1007 C  CB  . SER A 1 185 ? 108.482 148.509 143.915 1.00 110.22 ? 185 SER A CB  1 
ATOM   1008 O  OG  . SER A 1 185 ? 107.794 147.728 144.874 1.00 116.17 ? 185 SER A OG  1 
ATOM   1009 N  N   . ILE A 1 186 ? 110.963 148.439 141.950 1.00 116.44 ? 186 ILE A N   1 
ATOM   1010 C  CA  . ILE A 1 186 ? 111.911 149.121 141.076 1.00 110.92 ? 186 ILE A CA  1 
ATOM   1011 C  C   . ILE A 1 186 ? 111.858 148.530 139.674 1.00 113.08 ? 186 ILE A C   1 
ATOM   1012 O  O   . ILE A 1 186 ? 111.880 149.260 138.678 1.00 122.40 ? 186 ILE A O   1 
ATOM   1013 C  CB  . ILE A 1 186 ? 113.330 149.051 141.670 1.00 112.75 ? 186 ILE A CB  1 
ATOM   1014 C  CG1 . ILE A 1 186 ? 113.455 149.987 142.872 1.00 113.33 ? 186 ILE A CG1 1 
ATOM   1015 C  CG2 . ILE A 1 186 ? 114.369 149.400 140.622 1.00 114.39 ? 186 ILE A CG2 1 
ATOM   1016 C  CD1 . ILE A 1 186 ? 112.880 151.362 142.638 1.00 114.10 ? 186 ILE A CD1 1 
ATOM   1017 N  N   . ALA A 1 187 ? 111.786 147.202 139.574 1.00 109.09 ? 187 ALA A N   1 
ATOM   1018 C  CA  . ALA A 1 187 ? 111.722 146.559 138.266 1.00 110.02 ? 187 ALA A CA  1 
ATOM   1019 C  C   . ALA A 1 187 ? 110.442 146.926 137.525 1.00 115.45 ? 187 ALA A C   1 
ATOM   1020 O  O   . ALA A 1 187 ? 110.467 147.182 136.314 1.00 122.48 ? 187 ALA A O   1 
ATOM   1021 C  CB  . ALA A 1 187 ? 111.836 145.045 138.421 1.00 113.59 ? 187 ALA A CB  1 
ATOM   1022 N  N   . VAL A 1 188 ? 109.312 146.955 138.232 1.00 115.36 ? 188 VAL A N   1 
ATOM   1023 C  CA  . VAL A 1 188 ? 108.052 147.329 137.593 1.00 117.74 ? 188 VAL A CA  1 
ATOM   1024 C  C   . VAL A 1 188 ? 108.111 148.770 137.104 1.00 122.58 ? 188 VAL A C   1 
ATOM   1025 O  O   . VAL A 1 188 ? 107.677 149.081 135.986 1.00 128.49 ? 188 VAL A O   1 
ATOM   1026 C  CB  . VAL A 1 188 ? 106.875 147.100 138.559 1.00 116.24 ? 188 VAL A CB  1 
ATOM   1027 C  CG1 . VAL A 1 188 ? 105.670 147.914 138.132 1.00 114.62 ? 188 VAL A CG1 1 
ATOM   1028 C  CG2 . VAL A 1 188 ? 106.524 145.629 138.614 1.00 117.11 ? 188 VAL A CG2 1 
ATOM   1029 N  N   . CYS A 1 189 ? 108.651 149.672 137.927 1.00 123.73 ? 189 CYS A N   1 
ATOM   1030 C  CA  . CYS A 1 189 ? 108.767 151.067 137.516 1.00 121.78 ? 189 CYS A CA  1 
ATOM   1031 C  C   . CYS A 1 189 ? 109.696 151.215 136.317 1.00 124.84 ? 189 CYS A C   1 
ATOM   1032 O  O   . CYS A 1 189 ? 109.428 152.011 135.411 1.00 129.23 ? 189 CYS A O   1 
ATOM   1033 C  CB  . CYS A 1 189 ? 109.256 151.919 138.684 1.00 126.21 ? 189 CYS A CB  1 
ATOM   1034 S  SG  . CYS A 1 189 ? 107.951 152.429 139.823 1.00 142.98 ? 189 CYS A SG  1 
ATOM   1035 N  N   . ALA A 1 190 ? 110.795 150.460 136.296 1.00 115.87 ? 190 ALA A N   1 
ATOM   1036 C  CA  . ALA A 1 190 ? 111.713 150.521 135.165 1.00 110.51 ? 190 ALA A CA  1 
ATOM   1037 C  C   . ALA A 1 190 ? 111.048 150.030 133.888 1.00 115.60 ? 190 ALA A C   1 
ATOM   1038 O  O   . ALA A 1 190 ? 111.227 150.622 132.818 1.00 126.95 ? 190 ALA A O   1 
ATOM   1039 C  CB  . ALA A 1 190 ? 112.969 149.705 135.462 1.00 106.26 ? 190 ALA A CB  1 
ATOM   1040 N  N   . ASN A 1 191 ? 110.277 148.945 133.978 1.00 116.78 ? 191 ASN A N   1 
ATOM   1041 C  CA  . ASN A 1 191 ? 109.574 148.449 132.800 1.00 117.15 ? 191 ASN A CA  1 
ATOM   1042 C  C   . ASN A 1 191 ? 108.539 149.454 132.313 1.00 120.08 ? 191 ASN A C   1 
ATOM   1043 O  O   . ASN A 1 191 ? 108.383 149.660 131.104 1.00 128.24 ? 191 ASN A O   1 
ATOM   1044 C  CB  . ASN A 1 191 ? 108.918 147.106 133.106 1.00 118.09 ? 191 ASN A CB  1 
ATOM   1045 C  CG  . ASN A 1 191 ? 109.797 145.937 132.732 1.00 120.45 ? 191 ASN A CG  1 
ATOM   1046 O  OD1 . ASN A 1 191 ? 110.020 145.032 133.533 1.00 124.44 ? 191 ASN A OD1 1 
ATOM   1047 N  ND2 . ASN A 1 191 ? 110.308 145.951 131.510 1.00 123.12 ? 191 ASN A ND2 1 
ATOM   1048 N  N   . LEU A 1 192 ? 107.821 150.091 133.240 1.00 119.32 ? 192 LEU A N   1 
ATOM   1049 C  CA  . LEU A 1 192 ? 106.855 151.112 132.848 1.00 118.40 ? 192 LEU A CA  1 
ATOM   1050 C  C   . LEU A 1 192 ? 107.540 152.288 132.167 1.00 126.08 ? 192 LEU A C   1 
ATOM   1051 O  O   . LEU A 1 192 ? 107.045 152.810 131.161 1.00 136.56 ? 192 LEU A O   1 
ATOM   1052 C  CB  . LEU A 1 192 ? 106.068 151.586 134.067 1.00 120.86 ? 192 LEU A CB  1 
ATOM   1053 C  CG  . LEU A 1 192 ? 104.822 150.776 134.418 1.00 124.72 ? 192 LEU A CG  1 
ATOM   1054 C  CD1 . LEU A 1 192 ? 104.347 151.113 135.818 1.00 125.80 ? 192 LEU A CD1 1 
ATOM   1055 C  CD2 . LEU A 1 192 ? 103.726 151.030 133.402 1.00 126.13 ? 192 LEU A CD2 1 
ATOM   1056 N  N   . LEU A 1 193 ? 108.680 152.724 132.704 1.00 123.17 ? 193 LEU A N   1 
ATOM   1057 C  CA  . LEU A 1 193 ? 109.409 153.831 132.096 1.00 121.96 ? 193 LEU A CA  1 
ATOM   1058 C  C   . LEU A 1 193 ? 109.911 153.462 130.706 1.00 125.37 ? 193 LEU A C   1 
ATOM   1059 O  O   . LEU A 1 193 ? 109.844 154.276 129.778 1.00 127.29 ? 193 LEU A O   1 
ATOM   1060 C  CB  . LEU A 1 193 ? 110.569 154.247 132.997 1.00 121.59 ? 193 LEU A CB  1 
ATOM   1061 C  CG  . LEU A 1 193 ? 111.594 155.211 132.404 1.00 128.08 ? 193 LEU A CG  1 
ATOM   1062 C  CD1 . LEU A 1 193 ? 111.029 156.618 132.348 1.00 127.37 ? 193 LEU A CD1 1 
ATOM   1063 C  CD2 . LEU A 1 193 ? 112.879 155.179 133.212 1.00 126.16 ? 193 LEU A CD2 1 
ATOM   1064 N  N   . MET A 1 194 ? 110.417 152.238 130.544 1.00 125.86 ? 194 MET A N   1 
ATOM   1065 C  CA  . MET A 1 194 ? 110.863 151.793 129.228 1.00 120.72 ? 194 MET A CA  1 
ATOM   1066 C  C   . MET A 1 194 ? 109.708 151.760 128.238 1.00 127.13 ? 194 MET A C   1 
ATOM   1067 O  O   . MET A 1 194 ? 109.857 152.182 127.085 1.00 137.63 ? 194 MET A O   1 
ATOM   1068 C  CB  . MET A 1 194 ? 111.516 150.416 129.331 1.00 121.62 ? 194 MET A CB  1 
ATOM   1069 C  CG  . MET A 1 194 ? 112.937 150.439 129.851 1.00 126.32 ? 194 MET A CG  1 
ATOM   1070 S  SD  . MET A 1 194 ? 113.350 148.962 130.796 1.00 142.01 ? 194 MET A SD  1 
ATOM   1071 C  CE  . MET A 1 194 ? 113.676 147.796 129.480 1.00 128.22 ? 194 MET A CE  1 
ATOM   1072 N  N   . ALA A 1 195 ? 108.547 151.259 128.667 1.00 125.68 ? 195 ALA A N   1 
ATOM   1073 C  CA  . ALA A 1 195 ? 107.387 151.226 127.784 1.00 123.26 ? 195 ALA A CA  1 
ATOM   1074 C  C   . ALA A 1 195 ? 106.953 152.631 127.390 1.00 127.66 ? 195 ALA A C   1 
ATOM   1075 O  O   . ALA A 1 195 ? 106.623 152.882 126.225 1.00 135.36 ? 195 ALA A O   1 
ATOM   1076 C  CB  . ALA A 1 195 ? 106.236 150.480 128.454 1.00 122.57 ? 195 ALA A CB  1 
ATOM   1077 N  N   . PHE A 1 196 ? 106.942 153.559 128.348 1.00 128.46 ? 196 PHE A N   1 
ATOM   1078 C  CA  . PHE A 1 196 ? 106.565 154.934 128.039 1.00 129.86 ? 196 PHE A CA  1 
ATOM   1079 C  C   . PHE A 1 196 ? 107.543 155.568 127.058 1.00 132.71 ? 196 PHE A C   1 
ATOM   1080 O  O   . PHE A 1 196 ? 107.131 156.251 126.112 1.00 135.49 ? 196 PHE A O   1 
ATOM   1081 C  CB  . PHE A 1 196 ? 106.486 155.755 129.324 1.00 129.38 ? 196 PHE A CB  1 
ATOM   1082 C  CG  . PHE A 1 196 ? 106.251 157.216 129.095 1.00 132.50 ? 196 PHE A CG  1 
ATOM   1083 C  CD1 . PHE A 1 196 ? 105.031 157.669 128.628 1.00 132.86 ? 196 PHE A CD1 1 
ATOM   1084 C  CD2 . PHE A 1 196 ? 107.250 158.139 129.349 1.00 131.75 ? 196 PHE A CD2 1 
ATOM   1085 C  CE1 . PHE A 1 196 ? 104.811 159.014 128.418 1.00 132.85 ? 196 PHE A CE1 1 
ATOM   1086 C  CE2 . PHE A 1 196 ? 107.037 159.486 129.140 1.00 132.92 ? 196 PHE A CE2 1 
ATOM   1087 C  CZ  . PHE A 1 196 ? 105.816 159.924 128.674 1.00 135.65 ? 196 PHE A CZ  1 
ATOM   1088 N  N   . VAL A 1 197 ? 108.842 155.349 127.265 1.00 128.83 ? 197 VAL A N   1 
ATOM   1089 C  CA  . VAL A 1 197 ? 109.847 155.907 126.365 1.00 128.81 ? 197 VAL A CA  1 
ATOM   1090 C  C   . VAL A 1 197 ? 109.686 155.333 124.964 1.00 128.33 ? 197 VAL A C   1 
ATOM   1091 O  O   . VAL A 1 197 ? 109.767 156.060 123.966 1.00 129.22 ? 197 VAL A O   1 
ATOM   1092 C  CB  . VAL A 1 197 ? 111.259 155.655 126.924 1.00 127.80 ? 197 VAL A CB  1 
ATOM   1093 C  CG1 . VAL A 1 197 ? 112.299 155.778 125.826 1.00 125.76 ? 197 VAL A CG1 1 
ATOM   1094 C  CG2 . VAL A 1 197 ? 111.556 156.621 128.055 1.00 127.09 ? 197 VAL A CG2 1 
ATOM   1095 N  N   . LEU A 1 198 ? 109.456 154.023 124.866 1.00 128.24 ? 198 LEU A N   1 
ATOM   1096 C  CA  . LEU A 1 198 ? 109.283 153.404 123.557 1.00 128.64 ? 198 LEU A CA  1 
ATOM   1097 C  C   . LEU A 1 198 ? 108.028 153.916 122.861 1.00 132.54 ? 198 LEU A C   1 
ATOM   1098 O  O   . LEU A 1 198 ? 108.036 154.138 121.645 1.00 136.83 ? 198 LEU A O   1 
ATOM   1099 C  CB  . LEU A 1 198 ? 109.239 151.886 123.698 1.00 128.77 ? 198 LEU A CB  1 
ATOM   1100 C  CG  . LEU A 1 198 ? 110.587 151.236 124.001 1.00 126.85 ? 198 LEU A CG  1 
ATOM   1101 C  CD1 . LEU A 1 198 ? 110.418 149.749 124.212 1.00 127.64 ? 198 LEU A CD1 1 
ATOM   1102 C  CD2 . LEU A 1 198 ? 111.570 151.511 122.882 1.00 129.97 ? 198 LEU A CD2 1 
ATOM   1103 N  N   . HIS A 1 199 ? 106.939 154.104 123.609 1.00 136.49 ? 199 HIS A N   1 
ATOM   1104 C  CA  . HIS A 1 199 ? 105.729 154.660 123.012 1.00 136.38 ? 199 HIS A CA  1 
ATOM   1105 C  C   . HIS A 1 199 ? 105.964 156.079 122.517 1.00 138.48 ? 199 HIS A C   1 
ATOM   1106 O  O   . HIS A 1 199 ? 105.479 156.459 121.445 1.00 140.44 ? 199 HIS A O   1 
ATOM   1107 C  CB  . HIS A 1 199 ? 104.578 154.632 124.014 1.00 136.96 ? 199 HIS A CB  1 
ATOM   1108 C  CG  . HIS A 1 199 ? 103.279 155.115 123.449 1.00 139.90 ? 199 HIS A CG  1 
ATOM   1109 N  ND1 . HIS A 1 199 ? 102.581 156.175 123.986 1.00 141.22 ? 199 HIS A ND1 1 
ATOM   1110 C  CD2 . HIS A 1 199 ? 102.551 154.681 122.393 1.00 139.66 ? 199 HIS A CD2 1 
ATOM   1111 C  CE1 . HIS A 1 199 ? 101.479 156.373 123.285 1.00 141.01 ? 199 HIS A CE1 1 
ATOM   1112 N  NE2 . HIS A 1 199 ? 101.436 155.480 122.314 1.00 138.80 ? 199 HIS A NE2 1 
ATOM   1113 N  N   . GLN A 1 200 ? 106.696 156.883 123.291 1.00 139.70 ? 200 GLN A N   1 
ATOM   1114 C  CA  . GLN A 1 200 ? 107.007 158.239 122.852 1.00 141.77 ? 200 GLN A CA  1 
ATOM   1115 C  C   . GLN A 1 200 ? 107.860 158.229 121.590 1.00 143.36 ? 200 GLN A C   1 
ATOM   1116 O  O   . GLN A 1 200 ? 107.637 159.028 120.674 1.00 142.16 ? 200 GLN A O   1 
ATOM   1117 C  CB  . GLN A 1 200 ? 107.711 159.005 123.971 1.00 139.63 ? 200 GLN A CB  1 
ATOM   1118 C  CG  . GLN A 1 200 ? 106.766 159.575 125.012 1.00 143.40 ? 200 GLN A CG  1 
ATOM   1119 C  CD  . GLN A 1 200 ? 105.436 159.997 124.423 1.00 145.73 ? 200 GLN A CD  1 
ATOM   1120 O  OE1 . GLN A 1 200 ? 104.442 159.279 124.525 1.00 143.37 ? 200 GLN A OE1 1 
ATOM   1121 N  NE2 . GLN A 1 200 ? 105.410 161.171 123.803 1.00 143.57 ? 200 GLN A NE2 1 
ATOM   1122 N  N   . ALA A 1 201 ? 108.836 157.331 121.522 1.00 140.33 ? 201 ALA A N   1 
ATOM   1123 C  CA  . ALA A 1 201 ? 109.695 157.231 120.349 1.00 136.76 ? 201 ALA A CA  1 
ATOM   1124 C  C   . ALA A 1 201 ? 109.148 156.207 119.361 1.00 132.79 ? 201 ALA A C   1 
ATOM   1125 O  O   . ALA A 1 201 ? 108.551 156.566 118.347 1.00 131.02 ? 201 ALA A O   1 
ATOM   1126 C  CB  . ALA A 1 201 ? 111.111 156.869 120.757 1.00 134.36 ? 201 ALA A CB  1 
ATOM   1127 N  N   . THR A 1 230 ? 107.832 148.561 113.508 1.00 146.67 ? 230 THR A N   1 
ATOM   1128 C  CA  . THR A 1 230 ? 109.166 148.084 113.169 1.00 148.67 ? 230 THR A CA  1 
ATOM   1129 C  C   . THR A 1 230 ? 109.915 147.625 114.412 1.00 147.49 ? 230 THR A C   1 
ATOM   1130 O  O   . THR A 1 230 ? 109.349 146.958 115.280 1.00 146.69 ? 230 THR A O   1 
ATOM   1131 C  CB  . THR A 1 230 ? 109.992 149.171 112.460 1.00 148.08 ? 230 THR A CB  1 
ATOM   1132 O  OG1 . THR A 1 230 ? 110.032 150.349 113.275 1.00 141.13 ? 230 THR A OG1 1 
ATOM   1133 C  CG2 . THR A 1 230 ? 109.375 149.513 111.115 1.00 146.31 ? 230 THR A CG2 1 
ATOM   1134 N  N   . SER A 1 231 ? 111.197 147.988 114.486 1.00 144.07 ? 231 SER A N   1 
ATOM   1135 C  CA  . SER A 1 231 ? 112.007 147.612 115.639 1.00 142.68 ? 231 SER A CA  1 
ATOM   1136 C  C   . SER A 1 231 ? 111.475 148.248 116.916 1.00 144.33 ? 231 SER A C   1 
ATOM   1137 O  O   . SER A 1 231 ? 111.457 147.609 117.973 1.00 145.92 ? 231 SER A O   1 
ATOM   1138 C  CB  . SER A 1 231 ? 113.463 148.009 115.408 1.00 140.16 ? 231 SER A CB  1 
ATOM   1139 O  OG  . SER A 1 231 ? 113.621 149.415 115.478 1.00 141.49 ? 231 SER A OG  1 
ATOM   1140 N  N   . VAL A 1 232 ? 111.037 149.505 116.839 1.00 136.23 ? 232 VAL A N   1 
ATOM   1141 C  CA  . VAL A 1 232 ? 110.506 150.178 118.020 1.00 132.35 ? 232 VAL A CA  1 
ATOM   1142 C  C   . VAL A 1 232 ? 109.227 149.501 118.497 1.00 134.27 ? 232 VAL A C   1 
ATOM   1143 O  O   . VAL A 1 232 ? 109.030 149.298 119.699 1.00 139.66 ? 232 VAL A O   1 
ATOM   1144 C  CB  . VAL A 1 232 ? 110.287 151.673 117.730 1.00 132.23 ? 232 VAL A CB  1 
ATOM   1145 C  CG1 . VAL A 1 232 ? 109.539 152.330 118.872 1.00 133.09 ? 232 VAL A CG1 1 
ATOM   1146 C  CG2 . VAL A 1 232 ? 111.619 152.361 117.508 1.00 133.06 ? 232 VAL A CG2 1 
ATOM   1147 N  N   . ARG A 1 233 ? 108.339 149.138 117.570 1.00 136.27 ? 233 ARG A N   1 
ATOM   1148 C  CA  . ARG A 1 233 ? 107.109 148.452 117.960 1.00 139.38 ? 233 ARG A CA  1 
ATOM   1149 C  C   . ARG A 1 233 ? 107.399 147.071 118.537 1.00 142.16 ? 233 ARG A C   1 
ATOM   1150 O  O   . ARG A 1 233 ? 106.743 146.638 119.497 1.00 142.29 ? 233 ARG A O   1 
ATOM   1151 C  CB  . ARG A 1 233 ? 106.164 148.353 116.764 1.00 137.84 ? 233 ARG A CB  1 
ATOM   1152 C  CG  . ARG A 1 233 ? 104.797 147.770 117.090 1.00 137.54 ? 233 ARG A CG  1 
ATOM   1153 C  CD  . ARG A 1 233 ? 103.958 148.716 117.934 1.00 138.37 ? 233 ARG A CD  1 
ATOM   1154 N  NE  . ARG A 1 233 ? 104.320 150.114 117.734 1.00 142.15 ? 233 ARG A NE  1 
ATOM   1155 C  CZ  . ARG A 1 233 ? 103.727 151.133 118.340 1.00 142.08 ? 233 ARG A CZ  1 
ATOM   1156 N  NH1 . ARG A 1 233 ? 102.726 150.948 119.185 1.00 139.57 ? 233 ARG A NH1 1 
ATOM   1157 N  NH2 . ARG A 1 233 ? 104.150 152.370 118.093 1.00 139.97 ? 233 ARG A NH2 1 
ATOM   1158 N  N   . ALA A 1 234 ? 108.369 146.358 117.960 1.00 134.17 ? 234 ALA A N   1 
ATOM   1159 C  CA  . ALA A 1 234 ? 108.759 145.068 118.515 1.00 132.58 ? 234 ALA A CA  1 
ATOM   1160 C  C   . ALA A 1 234 ? 109.304 145.226 119.927 1.00 135.68 ? 234 ALA A C   1 
ATOM   1161 O  O   . ALA A 1 234 ? 108.970 144.442 120.825 1.00 139.33 ? 234 ALA A O   1 
ATOM   1162 C  CB  . ALA A 1 234 ? 109.792 144.400 117.610 1.00 133.59 ? 234 ALA A CB  1 
ATOM   1163 N  N   . ALA A 1 235 ? 110.138 146.243 120.146 1.00 128.18 ? 235 ALA A N   1 
ATOM   1164 C  CA  . ALA A 1 235 ? 110.633 146.514 121.488 1.00 127.53 ? 235 ALA A CA  1 
ATOM   1165 C  C   . ALA A 1 235 ? 109.490 146.863 122.429 1.00 130.68 ? 235 ALA A C   1 
ATOM   1166 O  O   . ALA A 1 235 ? 109.504 146.481 123.601 1.00 138.58 ? 235 ALA A O   1 
ATOM   1167 C  CB  . ALA A 1 235 ? 111.664 147.639 121.449 1.00 129.61 ? 235 ALA A CB  1 
ATOM   1168 N  N   . PHE A 1 236 ? 108.487 147.584 121.928 1.00 122.33 ? 236 PHE A N   1 
ATOM   1169 C  CA  . PHE A 1 236 ? 107.350 147.970 122.757 1.00 117.73 ? 236 PHE A CA  1 
ATOM   1170 C  C   . PHE A 1 236 ? 106.569 146.750 123.228 1.00 119.10 ? 236 PHE A C   1 
ATOM   1171 O  O   . PHE A 1 236 ? 106.240 146.628 124.414 1.00 126.79 ? 236 PHE A O   1 
ATOM   1172 C  CB  . PHE A 1 236 ? 106.447 148.922 121.975 1.00 120.86 ? 236 PHE A CB  1 
ATOM   1173 C  CG  . PHE A 1 236 ? 105.309 149.474 122.776 1.00 123.73 ? 236 PHE A CG  1 
ATOM   1174 C  CD1 . PHE A 1 236 ? 105.506 150.534 123.639 1.00 123.00 ? 236 PHE A CD1 1 
ATOM   1175 C  CD2 . PHE A 1 236 ? 104.040 148.940 122.657 1.00 124.02 ? 236 PHE A CD2 1 
ATOM   1176 C  CE1 . PHE A 1 236 ? 104.460 151.047 124.374 1.00 122.90 ? 236 PHE A CE1 1 
ATOM   1177 C  CE2 . PHE A 1 236 ? 102.991 149.449 123.389 1.00 121.02 ? 236 PHE A CE2 1 
ATOM   1178 C  CZ  . PHE A 1 236 ? 103.201 150.504 124.248 1.00 121.12 ? 236 PHE A CZ  1 
ATOM   1179 N  N   . VAL A 1 237 ? 106.263 145.828 122.314 1.00 119.57 ? 237 VAL A N   1 
ATOM   1180 C  CA  . VAL A 1 237 ? 105.501 144.647 122.718 1.00 126.12 ? 237 VAL A CA  1 
ATOM   1181 C  C   . VAL A 1 237 ? 106.345 143.743 123.616 1.00 127.42 ? 237 VAL A C   1 
ATOM   1182 O  O   . VAL A 1 237 ? 105.835 143.143 124.577 1.00 128.65 ? 237 VAL A O   1 
ATOM   1183 C  CB  . VAL A 1 237 ? 104.951 143.896 121.491 1.00 125.85 ? 237 VAL A CB  1 
ATOM   1184 C  CG1 . VAL A 1 237 ? 103.868 144.717 120.818 1.00 124.67 ? 237 VAL A CG1 1 
ATOM   1185 C  CG2 . VAL A 1 237 ? 106.051 143.567 120.508 1.00 126.53 ? 237 VAL A CG2 1 
ATOM   1186 N  N   . HIS A 1 238 ? 107.647 143.639 123.334 1.00 126.28 ? 238 HIS A N   1 
ATOM   1187 C  CA  . HIS A 1 238 ? 108.521 142.863 124.207 1.00 123.54 ? 238 HIS A CA  1 
ATOM   1188 C  C   . HIS A 1 238 ? 108.556 143.451 125.610 1.00 125.93 ? 238 HIS A C   1 
ATOM   1189 O  O   . HIS A 1 238 ? 108.532 142.714 126.602 1.00 130.86 ? 238 HIS A O   1 
ATOM   1190 C  CB  . HIS A 1 238 ? 109.927 142.803 123.618 1.00 122.21 ? 238 HIS A CB  1 
ATOM   1191 C  CG  . HIS A 1 238 ? 110.823 141.820 124.301 1.00 122.93 ? 238 HIS A CG  1 
ATOM   1192 N  ND1 . HIS A 1 238 ? 111.085 140.571 123.785 1.00 129.86 ? 238 HIS A ND1 1 
ATOM   1193 C  CD2 . HIS A 1 238 ? 111.518 141.901 125.459 1.00 126.04 ? 238 HIS A CD2 1 
ATOM   1194 C  CE1 . HIS A 1 238 ? 111.903 139.924 124.594 1.00 129.96 ? 238 HIS A CE1 1 
ATOM   1195 N  NE2 . HIS A 1 238 ? 112.182 140.710 125.618 1.00 131.84 ? 238 HIS A NE2 1 
ATOM   1196 N  N   . VAL A 1 239 ? 108.614 144.779 125.713 1.00 119.38 ? 239 VAL A N   1 
ATOM   1197 C  CA  . VAL A 1 239 ? 108.619 145.430 127.015 1.00 116.77 ? 239 VAL A CA  1 
ATOM   1198 C  C   . VAL A 1 239 ? 107.281 145.243 127.714 1.00 121.50 ? 239 VAL A C   1 
ATOM   1199 O  O   . VAL A 1 239 ? 107.231 145.128 128.939 1.00 128.99 ? 239 VAL A O   1 
ATOM   1200 C  CB  . VAL A 1 239 ? 108.991 146.915 126.858 1.00 116.17 ? 239 VAL A CB  1 
ATOM   1201 C  CG1 . VAL A 1 239 ? 108.566 147.713 128.070 1.00 116.88 ? 239 VAL A CG1 1 
ATOM   1202 C  CG2 . VAL A 1 239 ? 110.484 147.049 126.645 1.00 119.92 ? 239 VAL A CG2 1 
ATOM   1203 N  N   . LEU A 1 240 ? 106.180 145.201 126.962 1.00 117.16 ? 240 LEU A N   1 
ATOM   1204 C  CA  . LEU A 1 240 ? 104.890 144.911 127.583 1.00 116.05 ? 240 LEU A CA  1 
ATOM   1205 C  C   . LEU A 1 240 ? 104.874 143.514 128.198 1.00 120.44 ? 240 LEU A C   1 
ATOM   1206 O  O   . LEU A 1 240 ? 104.376 143.321 129.316 1.00 124.25 ? 240 LEU A O   1 
ATOM   1207 C  CB  . LEU A 1 240 ? 103.769 145.062 126.559 1.00 115.89 ? 240 LEU A CB  1 
ATOM   1208 C  CG  . LEU A 1 240 ? 103.376 146.500 126.220 1.00 121.02 ? 240 LEU A CG  1 
ATOM   1209 C  CD1 . LEU A 1 240 ? 102.050 146.528 125.485 1.00 125.35 ? 240 LEU A CD1 1 
ATOM   1210 C  CD2 . LEU A 1 240 ? 103.314 147.353 127.473 1.00 114.60 ? 240 LEU A CD2 1 
ATOM   1211 N  N   . GLY A 1 241 ? 105.418 142.527 127.486 1.00 121.68 ? 241 GLY A N   1 
ATOM   1212 C  CA  . GLY A 1 241 ? 105.528 141.194 128.069 1.00 122.50 ? 241 GLY A CA  1 
ATOM   1213 C  C   . GLY A 1 241 ? 106.431 141.162 129.291 1.00 125.06 ? 241 GLY A C   1 
ATOM   1214 O  O   . GLY A 1 241 ? 106.104 140.535 130.310 1.00 128.25 ? 241 GLY A O   1 
ATOM   1215 N  N   . ASP A 1 242 ? 107.584 141.833 129.201 1.00 121.46 ? 242 ASP A N   1 
ATOM   1216 C  CA  . ASP A 1 242 ? 108.466 141.973 130.354 1.00 119.65 ? 242 ASP A CA  1 
ATOM   1217 C  C   . ASP A 1 242 ? 107.720 142.576 131.536 1.00 122.67 ? 242 ASP A C   1 
ATOM   1218 O  O   . ASP A 1 242 ? 107.899 142.148 132.681 1.00 130.97 ? 242 ASP A O   1 
ATOM   1219 C  CB  . ASP A 1 242 ? 109.666 142.853 130.000 1.00 127.41 ? 242 ASP A CB  1 
ATOM   1220 C  CG  . ASP A 1 242 ? 110.692 142.154 129.119 1.00 131.70 ? 242 ASP A CG  1 
ATOM   1221 O  OD1 . ASP A 1 242 ? 110.464 141.013 128.671 1.00 134.81 ? 242 ASP A OD1 1 
ATOM   1222 O  OD2 . ASP A 1 242 ? 111.750 142.769 128.874 1.00 129.67 ? 242 ASP A OD2 1 
ATOM   1223 N  N   . LEU A 1 243 ? 106.881 143.578 131.271 1.00 110.95 ? 243 LEU A N   1 
ATOM   1224 C  CA  . LEU A 1 243 ? 106.145 144.256 132.329 1.00 113.87 ? 243 LEU A CA  1 
ATOM   1225 C  C   . LEU A 1 243 ? 105.111 143.337 132.958 1.00 114.96 ? 243 LEU A C   1 
ATOM   1226 O  O   . LEU A 1 243 ? 104.881 143.394 134.168 1.00 116.56 ? 243 LEU A O   1 
ATOM   1227 C  CB  . LEU A 1 243 ? 105.480 145.513 131.772 1.00 111.09 ? 243 LEU A CB  1 
ATOM   1228 C  CG  . LEU A 1 243 ? 104.552 146.283 132.707 1.00 112.41 ? 243 LEU A CG  1 
ATOM   1229 C  CD1 . LEU A 1 243 ? 105.303 146.736 133.942 1.00 117.19 ? 243 LEU A CD1 1 
ATOM   1230 C  CD2 . LEU A 1 243 ? 103.947 147.469 131.983 1.00 115.82 ? 243 LEU A CD2 1 
ATOM   1231 N  N   . LEU A 1 244 ? 104.469 142.492 132.152 1.00 111.77 ? 244 LEU A N   1 
ATOM   1232 C  CA  . LEU A 1 244 ? 103.539 141.518 132.717 1.00 110.21 ? 244 LEU A CA  1 
ATOM   1233 C  C   . LEU A 1 244 ? 104.259 140.548 133.649 1.00 114.84 ? 244 LEU A C   1 
ATOM   1234 O  O   . LEU A 1 244 ? 103.778 140.253 134.755 1.00 121.02 ? 244 LEU A O   1 
ATOM   1235 C  CB  . LEU A 1 244 ? 102.832 140.761 131.597 1.00 111.92 ? 244 LEU A CB  1 
ATOM   1236 C  CG  . LEU A 1 244 ? 101.424 140.270 131.921 1.00 114.23 ? 244 LEU A CG  1 
ATOM   1237 C  CD1 . LEU A 1 244 ? 100.459 141.439 131.972 1.00 112.36 ? 244 LEU A CD1 1 
ATOM   1238 C  CD2 . LEU A 1 244 ? 100.975 139.244 130.898 1.00 117.79 ? 244 LEU A CD2 1 
ATOM   1239 N  N   . GLN A 1 245 ? 105.424 140.051 133.227 1.00 117.80 ? 245 GLN A N   1 
ATOM   1240 C  CA  . GLN A 1 245 ? 106.191 139.166 134.101 1.00 111.59 ? 245 GLN A CA  1 
ATOM   1241 C  C   . GLN A 1 245 ? 106.620 139.885 135.376 1.00 115.30 ? 245 GLN A C   1 
ATOM   1242 O  O   . GLN A 1 245 ? 106.582 139.308 136.473 1.00 120.24 ? 245 GLN A O   1 
ATOM   1243 C  CB  . GLN A 1 245 ? 107.409 138.617 133.364 1.00 118.02 ? 245 GLN A CB  1 
ATOM   1244 C  CG  . GLN A 1 245 ? 107.881 137.274 133.882 1.00 122.30 ? 245 GLN A CG  1 
ATOM   1245 C  CD  . GLN A 1 245 ? 109.371 137.078 133.710 1.00 122.54 ? 245 GLN A CD  1 
ATOM   1246 O  OE1 . GLN A 1 245 ? 109.985 137.650 132.812 1.00 124.03 ? 245 GLN A OE1 1 
ATOM   1247 N  NE2 . GLN A 1 245 ? 109.963 136.262 134.574 1.00 118.08 ? 245 GLN A NE2 1 
ATOM   1248 N  N   . SER A 1 246 ? 107.037 141.146 135.250 1.00 113.70 ? 246 SER A N   1 
ATOM   1249 C  CA  . SER A 1 246 ? 107.436 141.917 136.421 1.00 108.78 ? 246 SER A CA  1 
ATOM   1250 C  C   . SER A 1 246 ? 106.259 142.141 137.358 1.00 110.45 ? 246 SER A C   1 
ATOM   1251 O  O   . SER A 1 246 ? 106.427 142.166 138.579 1.00 114.33 ? 246 SER A O   1 
ATOM   1252 C  CB  . SER A 1 246 ? 108.040 143.250 135.989 1.00 114.51 ? 246 SER A CB  1 
ATOM   1253 O  OG  . SER A 1 246 ? 109.259 143.051 135.297 1.00 121.96 ? 246 SER A OG  1 
ATOM   1254 N  N   . PHE A 1 247 ? 105.059 142.317 136.805 1.00 109.86 ? 247 PHE A N   1 
ATOM   1255 C  CA  . PHE A 1 247 ? 103.871 142.451 137.639 1.00 108.32 ? 247 PHE A CA  1 
ATOM   1256 C  C   . PHE A 1 247 ? 103.597 141.168 138.407 1.00 109.06 ? 247 PHE A C   1 
ATOM   1257 O  O   . PHE A 1 247 ? 103.217 141.208 139.583 1.00 116.26 ? 247 PHE A O   1 
ATOM   1258 C  CB  . PHE A 1 247 ? 102.667 142.828 136.781 1.00 109.57 ? 247 PHE A CB  1 
ATOM   1259 C  CG  . PHE A 1 247 ? 102.285 144.272 136.883 1.00 115.45 ? 247 PHE A CG  1 
ATOM   1260 C  CD1 . PHE A 1 247 ? 102.090 144.862 138.117 1.00 116.90 ? 247 PHE A CD1 1 
ATOM   1261 C  CD2 . PHE A 1 247 ? 102.129 145.041 135.746 1.00 114.13 ? 247 PHE A CD2 1 
ATOM   1262 C  CE1 . PHE A 1 247 ? 101.742 146.191 138.215 1.00 117.01 ? 247 PHE A CE1 1 
ATOM   1263 C  CE2 . PHE A 1 247 ? 101.781 146.370 135.837 1.00 114.93 ? 247 PHE A CE2 1 
ATOM   1264 C  CZ  . PHE A 1 247 ? 101.587 146.946 137.073 1.00 117.25 ? 247 PHE A CZ  1 
ATOM   1265 N  N   . GLY A 1 248 ? 103.776 140.019 137.757 1.00 102.39 ? 248 GLY A N   1 
ATOM   1266 C  CA  . GLY A 1 248 ? 103.644 138.759 138.476 1.00 104.60 ? 248 GLY A CA  1 
ATOM   1267 C  C   . GLY A 1 248 ? 104.642 138.632 139.614 1.00 108.60 ? 248 GLY A C   1 
ATOM   1268 O  O   . GLY A 1 248 ? 104.288 138.234 140.732 1.00 112.39 ? 248 GLY A O   1 
ATOM   1269 N  N   . VAL A 1 249 ? 105.902 138.985 139.348 1.00 108.38 ? 249 VAL A N   1 
ATOM   1270 C  CA  . VAL A 1 249 ? 106.926 138.929 140.391 1.00 100.90 ? 249 VAL A CA  1 
ATOM   1271 C  C   . VAL A 1 249 ? 106.587 139.888 141.526 1.00 100.37 ? 249 VAL A C   1 
ATOM   1272 O  O   . VAL A 1 249 ? 106.785 139.573 142.705 1.00 101.98 ? 249 VAL A O   1 
ATOM   1273 C  CB  . VAL A 1 249 ? 108.314 139.228 139.796 1.00 103.72 ? 249 VAL A CB  1 
ATOM   1274 C  CG1 . VAL A 1 249 ? 109.360 139.278 140.893 1.00 101.76 ? 249 VAL A CG1 1 
ATOM   1275 C  CG2 . VAL A 1 249 ? 108.682 138.184 138.763 1.00 106.34 ? 249 VAL A CG2 1 
ATOM   1276 N  N   . LEU A 1 250 ? 106.078 141.073 141.190 1.00 105.00 ? 250 LEU A N   1 
ATOM   1277 C  CA  . LEU A 1 250 ? 105.704 142.042 142.214 1.00 102.82 ? 250 LEU A CA  1 
ATOM   1278 C  C   . LEU A 1 250 ? 104.549 141.534 143.063 1.00 107.17 ? 250 LEU A C   1 
ATOM   1279 O  O   . LEU A 1 250 ? 104.519 141.763 144.274 1.00 114.84 ? 250 LEU A O   1 
ATOM   1280 C  CB  . LEU A 1 250 ? 105.346 143.379 141.569 1.00 103.49 ? 250 LEU A CB  1 
ATOM   1281 C  CG  . LEU A 1 250 ? 104.577 144.362 142.450 1.00 99.53  ? 250 LEU A CG  1 
ATOM   1282 C  CD1 . LEU A 1 250 ? 105.460 144.881 143.564 1.00 98.06  ? 250 LEU A CD1 1 
ATOM   1283 C  CD2 . LEU A 1 250 ? 104.030 145.507 141.622 1.00 106.80 ? 250 LEU A CD2 1 
ATOM   1284 N  N   . ALA A 1 251 ? 103.577 140.860 142.445 1.00 106.02 ? 251 ALA A N   1 
ATOM   1285 C  CA  . ALA A 1 251 ? 102.487 140.277 143.221 1.00 103.59 ? 251 ALA A CA  1 
ATOM   1286 C  C   . ALA A 1 251 ? 103.007 139.220 144.186 1.00 107.85 ? 251 ALA A C   1 
ATOM   1287 O  O   . ALA A 1 251 ? 102.600 139.175 145.356 1.00 110.02 ? 251 ALA A O   1 
ATOM   1288 C  CB  . ALA A 1 251 ? 101.436 139.683 142.288 1.00 104.30 ? 251 ALA A CB  1 
ATOM   1289 N  N   . ALA A 1 252 ? 103.921 138.367 143.716 1.00 111.62 ? 252 ALA A N   1 
ATOM   1290 C  CA  . ALA A 1 252 ? 104.513 137.373 144.608 1.00 110.41 ? 252 ALA A CA  1 
ATOM   1291 C  C   . ALA A 1 252 ? 105.259 138.038 145.760 1.00 114.48 ? 252 ALA A C   1 
ATOM   1292 O  O   . ALA A 1 252 ? 105.154 137.607 146.915 1.00 118.52 ? 252 ALA A O   1 
ATOM   1293 C  CB  . ALA A 1 252 ? 105.447 136.452 143.826 1.00 107.91 ? 252 ALA A CB  1 
ATOM   1294 N  N   . SER A 1 253 ? 106.017 139.096 145.461 1.00 116.25 ? 253 SER A N   1 
ATOM   1295 C  CA  . SER A 1 253 ? 106.766 139.801 146.496 1.00 104.18 ? 253 SER A CA  1 
ATOM   1296 C  C   . SER A 1 253 ? 105.836 140.459 147.504 1.00 102.96 ? 253 SER A C   1 
ATOM   1297 O  O   . SER A 1 253 ? 106.117 140.462 148.707 1.00 110.87 ? 253 SER A O   1 
ATOM   1298 C  CB  . SER A 1 253 ? 107.678 140.843 145.858 1.00 105.35 ? 253 SER A CB  1 
ATOM   1299 O  OG  . SER A 1 253 ? 106.917 141.872 145.255 1.00 118.45 ? 253 SER A OG  1 
ATOM   1300 N  N   . ILE A 1 254 ? 104.734 141.040 147.030 1.00 102.47 ? 254 ILE A N   1 
ATOM   1301 C  CA  . ILE A 1 254 ? 103.759 141.649 147.928 1.00 103.72 ? 254 ILE A CA  1 
ATOM   1302 C  C   . ILE A 1 254 ? 103.167 140.597 148.851 1.00 107.83 ? 254 ILE A C   1 
ATOM   1303 O  O   . ILE A 1 254 ? 103.010 140.824 150.057 1.00 108.35 ? 254 ILE A O   1 
ATOM   1304 C  CB  . ILE A 1 254 ? 102.664 142.367 147.119 1.00 103.76 ? 254 ILE A CB  1 
ATOM   1305 C  CG1 . ILE A 1 254 ? 103.188 143.684 146.554 1.00 108.85 ? 254 ILE A CG1 1 
ATOM   1306 C  CG2 . ILE A 1 254 ? 101.442 142.618 147.981 1.00 101.50 ? 254 ILE A CG2 1 
ATOM   1307 C  CD1 . ILE A 1 254 ? 102.103 144.585 146.015 1.00 109.32 ? 254 ILE A CD1 1 
ATOM   1308 N  N   . LEU A 1 255 ? 102.831 139.428 148.302 1.00 113.78 ? 255 LEU A N   1 
ATOM   1309 C  CA  . LEU A 1 255 ? 102.288 138.362 149.138 1.00 110.03 ? 255 LEU A CA  1 
ATOM   1310 C  C   . LEU A 1 255 ? 103.296 137.914 150.188 1.00 111.94 ? 255 LEU A C   1 
ATOM   1311 O  O   . LEU A 1 255 ? 102.939 137.714 151.354 1.00 115.58 ? 255 LEU A O   1 
ATOM   1312 C  CB  . LEU A 1 255 ? 101.861 137.179 148.272 1.00 110.46 ? 255 LEU A CB  1 
ATOM   1313 C  CG  . LEU A 1 255 ? 101.523 135.901 149.037 1.00 113.61 ? 255 LEU A CG  1 
ATOM   1314 C  CD1 . LEU A 1 255 ? 100.326 136.128 149.939 1.00 115.08 ? 255 LEU A CD1 1 
ATOM   1315 C  CD2 . LEU A 1 255 ? 101.263 134.760 148.076 1.00 115.24 ? 255 LEU A CD2 1 
ATOM   1316 N  N   . ILE A 1 256 ? 104.562 137.756 149.797 1.00 112.53 ? 256 ILE A N   1 
ATOM   1317 C  CA  . ILE A 1 256 ? 105.572 137.289 150.743 1.00 109.08 ? 256 ILE A CA  1 
ATOM   1318 C  C   . ILE A 1 256 ? 105.819 138.327 151.831 1.00 110.56 ? 256 ILE A C   1 
ATOM   1319 O  O   . ILE A 1 256 ? 105.965 137.986 153.011 1.00 117.35 ? 256 ILE A O   1 
ATOM   1320 C  CB  . ILE A 1 256 ? 106.873 136.929 150.005 1.00 106.11 ? 256 ILE A CB  1 
ATOM   1321 C  CG1 . ILE A 1 256 ? 106.659 135.710 149.112 1.00 108.31 ? 256 ILE A CG1 1 
ATOM   1322 C  CG2 . ILE A 1 256 ? 107.988 136.661 150.995 1.00 106.84 ? 256 ILE A CG2 1 
ATOM   1323 C  CD1 . ILE A 1 256 ? 107.926 135.197 148.481 1.00 112.19 ? 256 ILE A CD1 1 
ATOM   1324 N  N   . TYR A 1 257 ? 105.874 139.606 151.456 1.00 117.50 ? 257 TYR A N   1 
ATOM   1325 C  CA  . TYR A 1 257 ? 106.240 140.651 152.407 1.00 114.24 ? 257 TYR A CA  1 
ATOM   1326 C  C   . TYR A 1 257 ? 105.227 140.764 153.538 1.00 115.86 ? 257 TYR A C   1 
ATOM   1327 O  O   . TYR A 1 257 ? 105.605 140.883 154.709 1.00 119.14 ? 257 TYR A O   1 
ATOM   1328 C  CB  . TYR A 1 257 ? 106.378 141.985 151.675 1.00 117.49 ? 257 TYR A CB  1 
ATOM   1329 C  CG  . TYR A 1 257 ? 106.536 143.181 152.583 1.00 119.26 ? 257 TYR A CG  1 
ATOM   1330 C  CD1 . TYR A 1 257 ? 107.741 143.442 153.214 1.00 120.30 ? 257 TYR A CD1 1 
ATOM   1331 C  CD2 . TYR A 1 257 ? 105.481 144.054 152.801 1.00 121.20 ? 257 TYR A CD2 1 
ATOM   1332 C  CE1 . TYR A 1 257 ? 107.891 144.534 154.042 1.00 118.47 ? 257 TYR A CE1 1 
ATOM   1333 C  CE2 . TYR A 1 257 ? 105.621 145.149 153.627 1.00 123.43 ? 257 TYR A CE2 1 
ATOM   1334 C  CZ  . TYR A 1 257 ? 106.828 145.383 154.244 1.00 120.79 ? 257 TYR A CZ  1 
ATOM   1335 O  OH  . TYR A 1 257 ? 106.972 146.473 155.068 1.00 119.44 ? 257 TYR A OH  1 
ATOM   1336 N  N   . PHE A 1 258 ? 103.935 140.737 153.212 1.00 116.64 ? 258 PHE A N   1 
ATOM   1337 C  CA  . PHE A 1 258 ? 102.912 140.891 154.241 1.00 117.47 ? 258 PHE A CA  1 
ATOM   1338 C  C   . PHE A 1 258 ? 102.721 139.612 155.045 1.00 122.21 ? 258 PHE A C   1 
ATOM   1339 O  O   . PHE A 1 258 ? 102.466 139.670 156.253 1.00 122.79 ? 258 PHE A O   1 
ATOM   1340 C  CB  . PHE A 1 258 ? 101.593 141.323 153.607 1.00 120.64 ? 258 PHE A CB  1 
ATOM   1341 C  CG  . PHE A 1 258 ? 101.524 142.788 153.304 1.00 124.88 ? 258 PHE A CG  1 
ATOM   1342 C  CD1 . PHE A 1 258 ? 101.321 143.708 154.315 1.00 121.04 ? 258 PHE A CD1 1 
ATOM   1343 C  CD2 . PHE A 1 258 ? 101.671 143.247 152.008 1.00 124.38 ? 258 PHE A CD2 1 
ATOM   1344 C  CE1 . PHE A 1 258 ? 101.260 145.056 154.039 1.00 121.46 ? 258 PHE A CE1 1 
ATOM   1345 C  CE2 . PHE A 1 258 ? 101.611 144.593 151.728 1.00 123.08 ? 258 PHE A CE2 1 
ATOM   1346 C  CZ  . PHE A 1 258 ? 101.405 145.499 152.744 1.00 124.29 ? 258 PHE A CZ  1 
ATOM   1347 N  N   . LYS A 1 259 ? 102.840 138.453 154.398 1.00 125.94 ? 259 LYS A N   1 
ATOM   1348 C  CA  . LYS A 1 259 ? 102.681 137.153 155.047 1.00 123.21 ? 259 LYS A CA  1 
ATOM   1349 C  C   . LYS A 1 259 ? 103.981 136.382 154.876 1.00 121.24 ? 259 LYS A C   1 
ATOM   1350 O  O   . LYS A 1 259 ? 104.156 135.650 153.890 1.00 123.56 ? 259 LYS A O   1 
ATOM   1351 C  CB  . LYS A 1 259 ? 101.503 136.382 154.458 1.00 124.00 ? 259 LYS A CB  1 
ATOM   1352 C  CG  . LYS A 1 259 ? 100.216 137.181 154.376 1.00 123.31 ? 259 LYS A CG  1 
ATOM   1353 C  CD  . LYS A 1 259 ? 99.354  136.956 155.603 1.00 125.45 ? 259 LYS A CD  1 
ATOM   1354 C  CE  . LYS A 1 259 ? 97.960  137.523 155.407 1.00 127.00 ? 259 LYS A CE  1 
ATOM   1355 N  NZ  . LYS A 1 259 ? 97.983  138.997 155.212 1.00 125.30 ? 259 LYS A NZ  1 
ATOM   1356 N  N   . PRO A 1 260 ? 104.922 136.514 155.813 1.00 121.61 ? 260 PRO A N   1 
ATOM   1357 C  CA  . PRO A 1 260 ? 106.219 135.840 155.652 1.00 124.48 ? 260 PRO A CA  1 
ATOM   1358 C  C   . PRO A 1 260 ? 106.122 134.328 155.629 1.00 129.18 ? 260 PRO A C   1 
ATOM   1359 O  O   . PRO A 1 260 ? 107.055 133.673 155.151 1.00 130.72 ? 260 PRO A O   1 
ATOM   1360 C  CB  . PRO A 1 260 ? 107.023 136.328 156.865 1.00 121.03 ? 260 PRO A CB  1 
ATOM   1361 C  CG  . PRO A 1 260 ? 106.309 137.551 157.342 1.00 124.31 ? 260 PRO A CG  1 
ATOM   1362 C  CD  . PRO A 1 260 ? 104.868 137.329 157.035 1.00 122.96 ? 260 PRO A CD  1 
ATOM   1363 N  N   . GLN A 1 261 ? 105.032 133.750 156.134 1.00 129.70 ? 261 GLN A N   1 
ATOM   1364 C  CA  . GLN A 1 261 ? 104.898 132.300 156.151 1.00 126.93 ? 261 GLN A CA  1 
ATOM   1365 C  C   . GLN A 1 261 ? 104.763 131.711 154.754 1.00 130.97 ? 261 GLN A C   1 
ATOM   1366 O  O   . GLN A 1 261 ? 104.978 130.507 154.581 1.00 132.59 ? 261 GLN A O   1 
ATOM   1367 C  CB  . GLN A 1 261 ? 103.698 131.894 157.004 1.00 123.74 ? 261 GLN A CB  1 
ATOM   1368 C  CG  . GLN A 1 261 ? 102.370 131.973 156.279 1.00 128.57 ? 261 GLN A CG  1 
ATOM   1369 C  CD  . GLN A 1 261 ? 101.448 133.015 156.870 1.00 132.11 ? 261 GLN A CD  1 
ATOM   1370 O  OE1 . GLN A 1 261 ? 101.897 133.976 157.493 1.00 131.69 ? 261 GLN A OE1 1 
ATOM   1371 N  NE2 . GLN A 1 261 ? 100.148 132.831 156.678 1.00 129.81 ? 261 GLN A NE2 1 
ATOM   1372 N  N   . TYR A 1 262 ? 104.412 132.520 153.761 1.00 123.41 ? 262 TYR A N   1 
ATOM   1373 C  CA  . TYR A 1 262 ? 104.241 132.035 152.393 1.00 120.01 ? 262 TYR A CA  1 
ATOM   1374 C  C   . TYR A 1 262 ? 105.518 132.190 151.574 1.00 122.70 ? 262 TYR A C   1 
ATOM   1375 O  O   . TYR A 1 262 ? 105.508 132.760 150.487 1.00 128.17 ? 262 TYR A O   1 
ATOM   1376 C  CB  . TYR A 1 262 ? 103.080 132.761 151.728 1.00 119.15 ? 262 TYR A CB  1 
ATOM   1377 C  CG  . TYR A 1 262 ? 101.727 132.395 152.284 1.00 124.65 ? 262 TYR A CG  1 
ATOM   1378 C  CD1 . TYR A 1 262 ? 101.509 131.161 152.875 1.00 125.26 ? 262 TYR A CD1 1 
ATOM   1379 C  CD2 . TYR A 1 262 ? 100.666 133.284 152.215 1.00 125.67 ? 262 TYR A CD2 1 
ATOM   1380 C  CE1 . TYR A 1 262 ? 100.273 130.825 153.384 1.00 126.06 ? 262 TYR A CE1 1 
ATOM   1381 C  CE2 . TYR A 1 262 ? 99.427  132.956 152.720 1.00 124.62 ? 262 TYR A CE2 1 
ATOM   1382 C  CZ  . TYR A 1 262 ? 99.236  131.726 153.303 1.00 126.37 ? 262 TYR A CZ  1 
ATOM   1383 O  OH  . TYR A 1 262 ? 98.001  131.397 153.808 1.00 126.28 ? 262 TYR A OH  1 
ATOM   1384 N  N   . LYS A 1 263 ? 106.635 131.675 152.091 1.00 114.51 ? 263 LYS A N   1 
ATOM   1385 C  CA  . LYS A 1 263 ? 107.880 131.729 151.336 1.00 113.38 ? 263 LYS A CA  1 
ATOM   1386 C  C   . LYS A 1 263 ? 107.821 130.884 150.074 1.00 121.11 ? 263 LYS A C   1 
ATOM   1387 O  O   . LYS A 1 263 ? 108.603 131.120 149.148 1.00 128.72 ? 263 LYS A O   1 
ATOM   1388 C  CB  . LYS A 1 263 ? 109.053 131.263 152.195 1.00 118.18 ? 263 LYS A CB  1 
ATOM   1389 C  CG  . LYS A 1 263 ? 108.920 131.576 153.667 1.00 122.17 ? 263 LYS A CG  1 
ATOM   1390 C  CD  . LYS A 1 263 ? 110.039 130.925 154.463 1.00 125.34 ? 263 LYS A CD  1 
ATOM   1391 C  CE  . LYS A 1 263 ? 110.252 129.481 154.040 1.00 124.16 ? 263 LYS A CE  1 
ATOM   1392 N  NZ  . LYS A 1 263 ? 111.502 128.918 154.614 1.00 125.28 ? 263 LYS A NZ  1 
ATOM   1393 N  N   . ALA A 1 264 ? 106.911 129.913 150.013 1.00 118.27 ? 264 ALA A N   1 
ATOM   1394 C  CA  . ALA A 1 264 ? 106.830 129.019 148.868 1.00 117.53 ? 264 ALA A CA  1 
ATOM   1395 C  C   . ALA A 1 264 ? 106.382 129.723 147.597 1.00 121.98 ? 264 ALA A C   1 
ATOM   1396 O  O   . ALA A 1 264 ? 106.476 129.128 146.519 1.00 127.96 ? 264 ALA A O   1 
ATOM   1397 C  CB  . ALA A 1 264 ? 105.882 127.861 149.176 1.00 117.39 ? 264 ALA A CB  1 
ATOM   1398 N  N   . ALA A 1 265 ? 105.895 130.961 147.692 1.00 113.88 ? 265 ALA A N   1 
ATOM   1399 C  CA  . ALA A 1 265 ? 105.482 131.688 146.500 1.00 112.35 ? 265 ALA A CA  1 
ATOM   1400 C  C   . ALA A 1 265 ? 106.654 132.022 145.591 1.00 111.44 ? 265 ALA A C   1 
ATOM   1401 O  O   . ALA A 1 265 ? 106.445 132.278 144.402 1.00 117.97 ? 265 ALA A O   1 
ATOM   1402 C  CB  . ALA A 1 265 ? 104.748 132.969 146.892 1.00 111.19 ? 265 ALA A CB  1 
ATOM   1403 N  N   . ASP A 1 266 ? 107.874 132.027 146.115 1.00 117.31 ? 266 ASP A N   1 
ATOM   1404 C  CA  . ASP A 1 266 ? 109.042 132.344 145.304 1.00 121.47 ? 266 ASP A CA  1 
ATOM   1405 C  C   . ASP A 1 266 ? 109.448 131.160 144.427 1.00 127.15 ? 266 ASP A C   1 
ATOM   1406 O  O   . ASP A 1 266 ? 109.587 131.333 143.209 1.00 133.00 ? 266 ASP A O   1 
ATOM   1407 C  CB  . ASP A 1 266 ? 110.201 132.800 146.194 1.00 121.58 ? 266 ASP A CB  1 
ATOM   1408 C  CG  . ASP A 1 266 ? 111.438 133.155 145.404 1.00 134.87 ? 266 ASP A CG  1 
ATOM   1409 O  OD1 . ASP A 1 266 ? 111.298 133.623 144.255 1.00 138.41 ? 266 ASP A OD1 1 
ATOM   1410 O  OD2 . ASP A 1 266 ? 112.553 132.964 145.930 1.00 134.56 ? 266 ASP A OD2 1 
ATOM   1411 N  N   . PRO A 1 267 ? 109.664 129.954 144.977 1.00 112.38 ? 267 PRO A N   1 
ATOM   1412 C  CA  . PRO A 1 267 ? 109.968 128.819 144.089 1.00 116.58 ? 267 PRO A CA  1 
ATOM   1413 C  C   . PRO A 1 267 ? 108.850 128.497 143.112 1.00 124.04 ? 267 PRO A C   1 
ATOM   1414 O  O   . PRO A 1 267 ? 109.123 128.093 141.975 1.00 127.22 ? 267 PRO A O   1 
ATOM   1415 C  CB  . PRO A 1 267 ? 110.216 127.666 145.072 1.00 118.90 ? 267 PRO A CB  1 
ATOM   1416 C  CG  . PRO A 1 267 ? 110.554 128.325 146.352 1.00 115.28 ? 267 PRO A CG  1 
ATOM   1417 C  CD  . PRO A 1 267 ? 109.699 129.538 146.390 1.00 113.04 ? 267 PRO A CD  1 
ATOM   1418 N  N   . ILE A 1 268 ? 107.593 128.667 143.521 1.00 111.73 ? 268 ILE A N   1 
ATOM   1419 C  CA  . ILE A 1 268 ? 106.474 128.400 142.623 1.00 108.83 ? 268 ILE A CA  1 
ATOM   1420 C  C   . ILE A 1 268 ? 106.485 129.375 141.452 1.00 114.38 ? 268 ILE A C   1 
ATOM   1421 O  O   . ILE A 1 268 ? 106.301 128.985 140.291 1.00 120.01 ? 268 ILE A O   1 
ATOM   1422 C  CB  . ILE A 1 268 ? 105.146 128.459 143.396 1.00 105.75 ? 268 ILE A CB  1 
ATOM   1423 C  CG1 . ILE A 1 268 ? 105.012 127.245 144.313 1.00 105.14 ? 268 ILE A CG1 1 
ATOM   1424 C  CG2 . ILE A 1 268 ? 103.973 128.541 142.440 1.00 112.19 ? 268 ILE A CG2 1 
ATOM   1425 C  CD1 . ILE A 1 268 ? 103.942 127.395 145.362 1.00 110.09 ? 268 ILE A CD1 1 
ATOM   1426 N  N   . SER A 1 269 ? 106.698 130.660 141.741 1.00 112.17 ? 269 SER A N   1 
ATOM   1427 C  CA  . SER A 1 269 ? 106.795 131.648 140.674 1.00 112.57 ? 269 SER A CA  1 
ATOM   1428 C  C   . SER A 1 269 ? 107.983 131.358 139.771 1.00 117.49 ? 269 SER A C   1 
ATOM   1429 O  O   . SER A 1 269 ? 107.893 131.507 138.547 1.00 124.63 ? 269 SER A O   1 
ATOM   1430 C  CB  . SER A 1 269 ? 106.902 133.051 141.265 1.00 112.84 ? 269 SER A CB  1 
ATOM   1431 O  OG  . SER A 1 269 ? 106.065 133.186 142.396 1.00 121.00 ? 269 SER A OG  1 
ATOM   1432 N  N   . THR A 1 270 ? 109.107 130.943 140.358 1.00 112.08 ? 270 THR A N   1 
ATOM   1433 C  CA  . THR A 1 270 ? 110.265 130.581 139.552 1.00 112.74 ? 270 THR A CA  1 
ATOM   1434 C  C   . THR A 1 270 ? 109.931 129.442 138.601 1.00 123.09 ? 270 THR A C   1 
ATOM   1435 O  O   . THR A 1 270 ? 110.287 129.487 137.419 1.00 131.69 ? 270 THR A O   1 
ATOM   1436 C  CB  . THR A 1 270 ? 111.433 130.192 140.454 1.00 110.67 ? 270 THR A CB  1 
ATOM   1437 O  OG1 . THR A 1 270 ? 111.741 131.281 141.330 1.00 121.73 ? 270 THR A OG1 1 
ATOM   1438 C  CG2 . THR A 1 270 ? 112.655 129.855 139.623 1.00 115.36 ? 270 THR A CG2 1 
ATOM   1439 N  N   . PHE A 1 271 ? 109.231 128.422 139.097 1.00 123.16 ? 271 PHE A N   1 
ATOM   1440 C  CA  . PHE A 1 271 ? 108.842 127.302 138.247 1.00 119.25 ? 271 PHE A CA  1 
ATOM   1441 C  C   . PHE A 1 271 ? 107.937 127.762 137.112 1.00 119.39 ? 271 PHE A C   1 
ATOM   1442 O  O   . PHE A 1 271 ? 108.153 127.410 135.945 1.00 124.73 ? 271 PHE A O   1 
ATOM   1443 C  CB  . PHE A 1 271 ? 108.145 126.232 139.085 1.00 117.94 ? 271 PHE A CB  1 
ATOM   1444 C  CG  . PHE A 1 271 ? 108.971 125.002 139.300 1.00 123.04 ? 271 PHE A CG  1 
ATOM   1445 C  CD1 . PHE A 1 271 ? 109.821 124.907 140.385 1.00 124.96 ? 271 PHE A CD1 1 
ATOM   1446 C  CD2 . PHE A 1 271 ? 108.900 123.943 138.415 1.00 124.33 ? 271 PHE A CD2 1 
ATOM   1447 C  CE1 . PHE A 1 271 ? 110.582 123.779 140.587 1.00 127.60 ? 271 PHE A CE1 1 
ATOM   1448 C  CE2 . PHE A 1 271 ? 109.661 122.811 138.610 1.00 129.24 ? 271 PHE A CE2 1 
ATOM   1449 C  CZ  . PHE A 1 271 ? 110.504 122.729 139.698 1.00 130.71 ? 271 PHE A CZ  1 
ATOM   1450 N  N   . LEU A 1 272 ? 106.914 128.554 137.438 1.00 110.86 ? 272 LEU A N   1 
ATOM   1451 C  CA  . LEU A 1 272 ? 105.968 128.985 136.414 1.00 111.34 ? 272 LEU A CA  1 
ATOM   1452 C  C   . LEU A 1 272 ? 106.668 129.802 135.336 1.00 114.91 ? 272 LEU A C   1 
ATOM   1453 O  O   . LEU A 1 272 ? 106.479 129.568 134.135 1.00 123.91 ? 272 LEU A O   1 
ATOM   1454 C  CB  . LEU A 1 272 ? 104.837 129.789 137.050 1.00 111.03 ? 272 LEU A CB  1 
ATOM   1455 C  CG  . LEU A 1 272 ? 103.936 129.038 138.030 1.00 118.71 ? 272 LEU A CG  1 
ATOM   1456 C  CD1 . LEU A 1 272 ? 102.648 129.808 138.271 1.00 117.26 ? 272 LEU A CD1 1 
ATOM   1457 C  CD2 . LEU A 1 272 ? 103.643 127.638 137.525 1.00 117.26 ? 272 LEU A CD2 1 
ATOM   1458 N  N   . PHE A 1 273 ? 107.509 130.749 135.750 1.00 112.30 ? 273 PHE A N   1 
ATOM   1459 C  CA  . PHE A 1 273 ? 108.172 131.609 134.781 1.00 110.52 ? 273 PHE A CA  1 
ATOM   1460 C  C   . PHE A 1 273 ? 109.227 130.855 133.984 1.00 110.73 ? 273 PHE A C   1 
ATOM   1461 O  O   . PHE A 1 273 ? 109.437 131.157 132.807 1.00 116.81 ? 273 PHE A O   1 
ATOM   1462 C  CB  . PHE A 1 273 ? 108.775 132.815 135.493 1.00 114.04 ? 273 PHE A CB  1 
ATOM   1463 C  CG  . PHE A 1 273 ? 107.750 133.714 136.115 1.00 118.87 ? 273 PHE A CG  1 
ATOM   1464 C  CD1 . PHE A 1 273 ? 106.551 133.961 135.474 1.00 112.99 ? 273 PHE A CD1 1 
ATOM   1465 C  CD2 . PHE A 1 273 ? 107.977 134.301 137.346 1.00 117.70 ? 273 PHE A CD2 1 
ATOM   1466 C  CE1 . PHE A 1 273 ? 105.604 134.783 136.044 1.00 113.23 ? 273 PHE A CE1 1 
ATOM   1467 C  CE2 . PHE A 1 273 ? 107.031 135.120 137.920 1.00 114.75 ? 273 PHE A CE2 1 
ATOM   1468 C  CZ  . PHE A 1 273 ? 105.844 135.362 137.268 1.00 115.60 ? 273 PHE A CZ  1 
ATOM   1469 N  N   . SER A 1 274 ? 109.887 129.863 134.587 1.00 110.19 ? 274 SER A N   1 
ATOM   1470 C  CA  . SER A 1 274 ? 110.849 129.065 133.835 1.00 113.76 ? 274 SER A CA  1 
ATOM   1471 C  C   . SER A 1 274 ? 110.160 128.216 132.774 1.00 116.24 ? 274 SER A C   1 
ATOM   1472 O  O   . SER A 1 274 ? 110.645 128.118 131.639 1.00 122.52 ? 274 SER A O   1 
ATOM   1473 C  CB  . SER A 1 274 ? 111.655 128.188 134.789 1.00 116.62 ? 274 SER A CB  1 
ATOM   1474 O  OG  . SER A 1 274 ? 112.242 128.967 135.815 1.00 120.94 ? 274 SER A OG  1 
ATOM   1475 N  N   . ILE A 1 275 ? 109.032 127.591 133.121 1.00 113.46 ? 275 ILE A N   1 
ATOM   1476 C  CA  . ILE A 1 275 ? 108.268 126.852 132.117 1.00 115.13 ? 275 ILE A CA  1 
ATOM   1477 C  C   . ILE A 1 275 ? 107.802 127.785 131.007 1.00 115.06 ? 275 ILE A C   1 
ATOM   1478 O  O   . ILE A 1 275 ? 107.862 127.438 129.820 1.00 121.66 ? 275 ILE A O   1 
ATOM   1479 C  CB  . ILE A 1 275 ? 107.089 126.091 132.762 1.00 115.40 ? 275 ILE A CB  1 
ATOM   1480 C  CG1 . ILE A 1 275 ? 107.527 124.802 133.485 1.00 115.86 ? 275 ILE A CG1 1 
ATOM   1481 C  CG2 . ILE A 1 275 ? 106.024 125.769 131.729 1.00 114.53 ? 275 ILE A CG2 1 
ATOM   1482 C  CD1 . ILE A 1 275 ? 108.738 124.866 134.376 1.00 118.88 ? 275 ILE A CD1 1 
ATOM   1483 N  N   . CYS A 1 276 ? 107.339 128.984 131.368 1.00 117.70 ? 276 CYS A N   1 
ATOM   1484 C  CA  . CYS A 1 276 ? 106.925 129.941 130.346 1.00 113.52 ? 276 CYS A CA  1 
ATOM   1485 C  C   . CYS A 1 276 ? 108.090 130.316 129.436 1.00 118.79 ? 276 CYS A C   1 
ATOM   1486 O  O   . CYS A 1 276 ? 107.927 130.411 128.214 1.00 125.67 ? 276 CYS A O   1 
ATOM   1487 C  CB  . CYS A 1 276 ? 106.332 131.187 131.002 1.00 118.02 ? 276 CYS A CB  1 
ATOM   1488 S  SG  . CYS A 1 276 ? 104.538 131.136 131.216 1.00 136.81 ? 276 CYS A SG  1 
ATOM   1489 N  N   . ALA A 1 277 ? 109.275 130.525 130.012 1.00 119.67 ? 277 ALA A N   1 
ATOM   1490 C  CA  . ALA A 1 277 ? 110.441 130.886 129.212 1.00 117.43 ? 277 ALA A CA  1 
ATOM   1491 C  C   . ALA A 1 277 ? 110.824 129.769 128.250 1.00 120.21 ? 277 ALA A C   1 
ATOM   1492 O  O   . ALA A 1 277 ? 111.130 130.026 127.080 1.00 127.76 ? 277 ALA A O   1 
ATOM   1493 C  CB  . ALA A 1 277 ? 111.616 131.231 130.124 1.00 114.77 ? 277 ALA A CB  1 
ATOM   1494 N  N   . LEU A 1 278 ? 110.819 128.523 128.725 1.00 114.32 ? 278 LEU A N   1 
ATOM   1495 C  CA  . LEU A 1 278 ? 111.159 127.404 127.849 1.00 115.11 ? 278 LEU A CA  1 
ATOM   1496 C  C   . LEU A 1 278 ? 110.132 127.242 126.733 1.00 115.15 ? 278 LEU A C   1 
ATOM   1497 O  O   . LEU A 1 278 ? 110.491 126.996 125.572 1.00 118.96 ? 278 LEU A O   1 
ATOM   1498 C  CB  . LEU A 1 278 ? 111.279 126.122 128.668 1.00 114.91 ? 278 LEU A CB  1 
ATOM   1499 C  CG  . LEU A 1 278 ? 112.372 126.138 129.738 1.00 115.86 ? 278 LEU A CG  1 
ATOM   1500 C  CD1 . LEU A 1 278 ? 112.470 124.793 130.433 1.00 113.82 ? 278 LEU A CD1 1 
ATOM   1501 C  CD2 . LEU A 1 278 ? 113.707 126.529 129.136 1.00 120.98 ? 278 LEU A CD2 1 
ATOM   1502 N  N   . GLY A 1 279 ? 108.848 127.382 127.063 1.00 119.80 ? 279 GLY A N   1 
ATOM   1503 C  CA  . GLY A 1 279 ? 107.825 127.309 126.036 1.00 121.78 ? 279 GLY A CA  1 
ATOM   1504 C  C   . GLY A 1 279 ? 107.963 128.410 125.004 1.00 122.62 ? 279 GLY A C   1 
ATOM   1505 O  O   . GLY A 1 279 ? 107.713 128.197 123.816 1.00 129.31 ? 279 GLY A O   1 
ATOM   1506 N  N   . SER A 1 280 ? 108.362 129.605 125.443 1.00 125.61 ? 280 SER A N   1 
ATOM   1507 C  CA  . SER A 1 280 ? 108.573 130.697 124.502 1.00 128.93 ? 280 SER A CA  1 
ATOM   1508 C  C   . SER A 1 280 ? 109.807 130.468 123.640 1.00 127.12 ? 280 SER A C   1 
ATOM   1509 O  O   . SER A 1 280 ? 109.833 130.882 122.476 1.00 125.67 ? 280 SER A O   1 
ATOM   1510 C  CB  . SER A 1 280 ? 108.695 132.021 125.252 1.00 129.92 ? 280 SER A CB  1 
ATOM   1511 O  OG  . SER A 1 280 ? 110.035 132.249 125.649 1.00 131.64 ? 280 SER A OG  1 
ATOM   1512 N  N   . THR A 1 281 ? 110.839 129.831 124.190 1.00 117.39 ? 281 THR A N   1 
ATOM   1513 C  CA  . THR A 1 281 ? 112.062 129.609 123.431 1.00 121.47 ? 281 THR A CA  1 
ATOM   1514 C  C   . THR A 1 281 ? 111.983 128.405 122.501 1.00 121.24 ? 281 THR A C   1 
ATOM   1515 O  O   . THR A 1 281 ? 112.844 128.268 121.626 1.00 122.55 ? 281 THR A O   1 
ATOM   1516 C  CB  . THR A 1 281 ? 113.253 129.441 124.379 1.00 124.31 ? 281 THR A CB  1 
ATOM   1517 O  OG1 . THR A 1 281 ? 114.454 129.841 123.711 1.00 134.52 ? 281 THR A OG1 1 
ATOM   1518 C  CG2 . THR A 1 281 ? 113.394 127.997 124.815 1.00 116.75 ? 281 THR A CG2 1 
ATOM   1519 N  N   . ALA A 1 282 ? 110.991 127.532 122.672 1.00 117.89 ? 282 ALA A N   1 
ATOM   1520 C  CA  . ALA A 1 282 ? 110.875 126.371 121.788 1.00 115.54 ? 282 ALA A CA  1 
ATOM   1521 C  C   . ALA A 1 282 ? 110.758 126.725 120.305 1.00 114.32 ? 282 ALA A C   1 
ATOM   1522 O  O   . ALA A 1 282 ? 111.475 126.112 119.494 1.00 120.55 ? 282 ALA A O   1 
ATOM   1523 C  CB  . ALA A 1 282 ? 109.700 125.499 122.241 1.00 114.96 ? 282 ALA A CB  1 
ATOM   1524 N  N   . PRO A 1 283 ? 109.887 127.651 119.873 1.00 114.80 ? 283 PRO A N   1 
ATOM   1525 C  CA  . PRO A 1 283 ? 109.774 127.907 118.423 1.00 115.49 ? 283 PRO A CA  1 
ATOM   1526 C  C   . PRO A 1 283 ? 111.056 128.403 117.775 1.00 115.38 ? 283 PRO A C   1 
ATOM   1527 O  O   . PRO A 1 283 ? 111.372 128.006 116.644 1.00 119.31 ? 283 PRO A O   1 
ATOM   1528 C  CB  . PRO A 1 283 ? 108.662 128.963 118.343 1.00 115.91 ? 283 PRO A CB  1 
ATOM   1529 C  CG  . PRO A 1 283 ? 107.898 128.804 119.596 1.00 118.64 ? 283 PRO A CG  1 
ATOM   1530 C  CD  . PRO A 1 283 ? 108.907 128.447 120.631 1.00 117.42 ? 283 PRO A CD  1 
ATOM   1531 N  N   . THR A 1 284 ? 111.802 129.273 118.456 1.00 115.80 ? 284 THR A N   1 
ATOM   1532 C  CA  . THR A 1 284 ? 113.059 129.753 117.895 1.00 119.09 ? 284 THR A CA  1 
ATOM   1533 C  C   . THR A 1 284 ? 114.056 128.615 117.752 1.00 114.33 ? 284 THR A C   1 
ATOM   1534 O  O   . THR A 1 284 ? 114.795 128.547 116.764 1.00 117.13 ? 284 THR A O   1 
ATOM   1535 C  CB  . THR A 1 284 ? 113.640 130.865 118.764 1.00 119.14 ? 284 THR A CB  1 
ATOM   1536 O  OG1 . THR A 1 284 ? 114.087 130.315 120.008 1.00 119.90 ? 284 THR A OG1 1 
ATOM   1537 C  CG2 . THR A 1 284 ? 112.589 131.928 119.035 1.00 118.78 ? 284 THR A CG2 1 
ATOM   1538 N  N   . LEU A 1 285 ? 114.090 127.711 118.732 1.00 114.97 ? 285 LEU A N   1 
ATOM   1539 C  CA  . LEU A 1 285 ? 114.957 126.544 118.627 1.00 117.67 ? 285 LEU A CA  1 
ATOM   1540 C  C   . LEU A 1 285 ? 114.559 125.674 117.445 1.00 118.56 ? 285 LEU A C   1 
ATOM   1541 O  O   . LEU A 1 285 ? 115.422 125.167 116.721 1.00 122.08 ? 285 LEU A O   1 
ATOM   1542 C  CB  . LEU A 1 285 ? 114.912 125.740 119.925 1.00 119.08 ? 285 LEU A CB  1 
ATOM   1543 C  CG  . LEU A 1 285 ? 115.561 124.357 119.883 1.00 119.46 ? 285 LEU A CG  1 
ATOM   1544 C  CD1 . LEU A 1 285 ? 117.039 124.471 119.561 1.00 118.48 ? 285 LEU A CD1 1 
ATOM   1545 C  CD2 . LEU A 1 285 ? 115.353 123.630 121.197 1.00 121.43 ? 285 LEU A CD2 1 
ATOM   1546 N  N   . ARG A 1 286 ? 113.255 125.493 117.231 1.00 123.82 ? 286 ARG A N   1 
ATOM   1547 C  CA  . ARG A 1 286 ? 112.797 124.705 116.090 1.00 123.30 ? 286 ARG A CA  1 
ATOM   1548 C  C   . ARG A 1 286 ? 113.243 125.332 114.774 1.00 126.51 ? 286 ARG A C   1 
ATOM   1549 O  O   . ARG A 1 286 ? 113.749 124.641 113.881 1.00 130.98 ? 286 ARG A O   1 
ATOM   1550 C  CB  . ARG A 1 286 ? 111.277 124.564 116.132 1.00 123.71 ? 286 ARG A CB  1 
ATOM   1551 C  CG  . ARG A 1 286 ? 110.748 123.345 115.407 1.00 129.55 ? 286 ARG A CG  1 
ATOM   1552 C  CD  . ARG A 1 286 ? 109.507 123.680 114.602 1.00 130.62 ? 286 ARG A CD  1 
ATOM   1553 N  NE  . ARG A 1 286 ? 108.703 124.714 115.241 1.00 133.21 ? 286 ARG A NE  1 
ATOM   1554 C  CZ  . ARG A 1 286 ? 108.347 125.852 114.661 1.00 132.92 ? 286 ARG A CZ  1 
ATOM   1555 N  NH1 . ARG A 1 286 ? 108.713 126.139 113.423 1.00 130.37 ? 286 ARG A NH1 1 
ATOM   1556 N  NH2 . ARG A 1 286 ? 107.606 126.723 115.339 1.00 131.94 ? 286 ARG A NH2 1 
ATOM   1557 N  N   . ASP A 1 287 ? 113.067 126.648 114.642 1.00 124.08 ? 287 ASP A N   1 
ATOM   1558 C  CA  . ASP A 1 287 ? 113.467 127.327 113.412 1.00 119.31 ? 287 ASP A CA  1 
ATOM   1559 C  C   . ASP A 1 287 ? 114.974 127.246 113.194 1.00 118.13 ? 287 ASP A C   1 
ATOM   1560 O  O   . ASP A 1 287 ? 115.438 127.000 112.072 1.00 120.17 ? 287 ASP A O   1 
ATOM   1561 C  CB  . ASP A 1 287 ? 113.010 128.783 113.448 1.00 124.22 ? 287 ASP A CB  1 
ATOM   1562 C  CG  . ASP A 1 287 ? 111.618 128.968 112.887 1.00 133.16 ? 287 ASP A CG  1 
ATOM   1563 O  OD1 . ASP A 1 287 ? 111.016 127.965 112.449 1.00 132.33 ? 287 ASP A OD1 1 
ATOM   1564 O  OD2 . ASP A 1 287 ? 111.122 130.114 112.886 1.00 131.64 ? 287 ASP A OD2 1 
ATOM   1565 N  N   . VAL A 1 288 ? 115.753 127.452 114.257 1.00 113.98 ? 288 VAL A N   1 
ATOM   1566 C  CA  . VAL A 1 288 ? 117.206 127.393 114.143 1.00 108.22 ? 288 VAL A CA  1 
ATOM   1567 C  C   . VAL A 1 288 ? 117.653 125.996 113.739 1.00 110.15 ? 288 VAL A C   1 
ATOM   1568 O  O   . VAL A 1 288 ? 118.541 125.834 112.895 1.00 109.61 ? 288 VAL A O   1 
ATOM   1569 C  CB  . VAL A 1 288 ? 117.859 127.842 115.463 1.00 101.76 ? 288 VAL A CB  1 
ATOM   1570 C  CG1 . VAL A 1 288 ? 119.270 127.303 115.576 1.00 106.86 ? 288 VAL A CG1 1 
ATOM   1571 C  CG2 . VAL A 1 288 ? 117.859 129.354 115.559 1.00 102.94 ? 288 VAL A CG2 1 
ATOM   1572 N  N   . LEU A 1 289 ? 117.053 124.965 114.338 1.00 109.91 ? 289 LEU A N   1 
ATOM   1573 C  CA  . LEU A 1 289 ? 117.405 123.597 113.978 1.00 107.88 ? 289 LEU A CA  1 
ATOM   1574 C  C   . LEU A 1 289 ? 117.056 123.303 112.528 1.00 111.07 ? 289 LEU A C   1 
ATOM   1575 O  O   . LEU A 1 289 ? 117.822 122.637 111.822 1.00 115.04 ? 289 LEU A O   1 
ATOM   1576 C  CB  . LEU A 1 289 ? 116.700 122.612 114.907 1.00 107.17 ? 289 LEU A CB  1 
ATOM   1577 C  CG  . LEU A 1 289 ? 117.332 122.411 116.282 1.00 111.95 ? 289 LEU A CG  1 
ATOM   1578 C  CD1 . LEU A 1 289 ? 116.860 121.103 116.885 1.00 112.62 ? 289 LEU A CD1 1 
ATOM   1579 C  CD2 . LEU A 1 289 ? 118.847 122.446 116.188 1.00 110.69 ? 289 LEU A CD2 1 
ATOM   1580 N  N   . ARG A 1 290 ? 115.900 123.782 112.067 1.00 116.27 ? 290 ARG A N   1 
ATOM   1581 C  CA  . ARG A 1 290 ? 115.530 123.570 110.672 1.00 110.07 ? 290 ARG A CA  1 
ATOM   1582 C  C   . ARG A 1 290 ? 116.527 124.232 109.734 1.00 109.25 ? 290 ARG A C   1 
ATOM   1583 O  O   . ARG A 1 290 ? 116.905 123.653 108.709 1.00 115.13 ? 290 ARG A O   1 
ATOM   1584 C  CB  . ARG A 1 290 ? 114.122 124.099 110.414 1.00 113.56 ? 290 ARG A CB  1 
ATOM   1585 C  CG  . ARG A 1 290 ? 113.766 124.209 108.946 1.00 108.01 ? 290 ARG A CG  1 
ATOM   1586 C  CD  . ARG A 1 290 ? 112.350 123.742 108.698 1.00 110.79 ? 290 ARG A CD  1 
ATOM   1587 N  NE  . ARG A 1 290 ? 112.006 123.757 107.284 1.00 114.89 ? 290 ARG A NE  1 
ATOM   1588 C  CZ  . ARG A 1 290 ? 110.780 123.578 106.814 1.00 118.28 ? 290 ARG A CZ  1 
ATOM   1589 N  NH1 . ARG A 1 290 ? 109.755 123.366 107.623 1.00 116.58 ? 290 ARG A NH1 1 
ATOM   1590 N  NH2 . ARG A 1 290 ? 110.575 123.616 105.502 1.00 120.63 ? 290 ARG A NH2 1 
ATOM   1591 N  N   . ILE A 1 291 ? 116.966 125.447 110.065 1.00 104.51 ? 291 ILE A N   1 
ATOM   1592 C  CA  . ILE A 1 291 ? 117.956 126.122 109.230 1.00 101.52 ? 291 ILE A CA  1 
ATOM   1593 C  C   . ILE A 1 291 ? 119.276 125.361 109.242 1.00 105.64 ? 291 ILE A C   1 
ATOM   1594 O  O   . ILE A 1 291 ? 119.893 125.142 108.193 1.00 105.94 ? 291 ILE A O   1 
ATOM   1595 C  CB  . ILE A 1 291 ? 118.144 127.578 109.690 1.00 103.16 ? 291 ILE A CB  1 
ATOM   1596 C  CG1 . ILE A 1 291 ? 117.004 128.452 109.179 1.00 107.55 ? 291 ILE A CG1 1 
ATOM   1597 C  CG2 . ILE A 1 291 ? 119.468 128.124 109.199 1.00 102.87 ? 291 ILE A CG2 1 
ATOM   1598 C  CD1 . ILE A 1 291 ? 117.154 129.902 109.547 1.00 108.50 ? 291 ILE A CD1 1 
ATOM   1599 N  N   . LEU A 1 292 ? 119.722 124.936 110.425 1.00 103.74 ? 292 LEU A N   1 
ATOM   1600 C  CA  . LEU A 1 292 ? 121.041 124.326 110.549 1.00 99.25  ? 292 LEU A CA  1 
ATOM   1601 C  C   . LEU A 1 292 ? 121.096 122.945 109.914 1.00 102.18 ? 292 LEU A C   1 
ATOM   1602 O  O   . LEU A 1 292 ? 122.145 122.550 109.397 1.00 109.84 ? 292 LEU A O   1 
ATOM   1603 C  CB  . LEU A 1 292 ? 121.444 124.242 112.018 1.00 101.35 ? 292 LEU A CB  1 
ATOM   1604 C  CG  . LEU A 1 292 ? 121.965 125.528 112.656 1.00 105.51 ? 292 LEU A CG  1 
ATOM   1605 C  CD1 . LEU A 1 292 ? 122.508 125.244 114.041 1.00 109.07 ? 292 LEU A CD1 1 
ATOM   1606 C  CD2 . LEU A 1 292 ? 123.026 126.167 111.786 1.00 95.91  ? 292 LEU A CD2 1 
ATOM   1607 N  N   . MET A 1 293 ? 119.996 122.198 109.938 1.00 101.20 ? 293 MET A N   1 
ATOM   1608 C  CA  . MET A 1 293 ? 119.975 120.863 109.358 1.00 98.10  ? 293 MET A CA  1 
ATOM   1609 C  C   . MET A 1 293 ? 119.878 120.878 107.842 1.00 99.86  ? 293 MET A C   1 
ATOM   1610 O  O   . MET A 1 293 ? 119.612 119.829 107.250 1.00 111.21 ? 293 MET A O   1 
ATOM   1611 C  CB  . MET A 1 293 ? 118.815 120.051 109.936 1.00 101.16 ? 293 MET A CB  1 
ATOM   1612 C  CG  . MET A 1 293 ? 119.082 119.501 111.321 1.00 105.42 ? 293 MET A CG  1 
ATOM   1613 S  SD  . MET A 1 293 ? 119.819 117.860 111.311 1.00 115.01 ? 293 MET A SD  1 
ATOM   1614 C  CE  . MET A 1 293 ? 118.790 117.028 110.112 1.00 104.00 ? 293 MET A CE  1 
ATOM   1615 N  N   . GLU A 1 294 ? 120.085 122.033 107.210 1.00 97.93  ? 294 GLU A N   1 
ATOM   1616 C  CA  . GLU A 1 294 ? 120.026 122.164 105.756 1.00 100.15 ? 294 GLU A CA  1 
ATOM   1617 C  C   . GLU A 1 294 ? 118.643 121.810 105.219 1.00 103.11 ? 294 GLU A C   1 
ATOM   1618 O  O   . GLU A 1 294 ? 118.506 121.152 104.187 1.00 103.88 ? 294 GLU A O   1 
ATOM   1619 C  CB  . GLU A 1 294 ? 121.105 121.316 105.082 1.00 105.94 ? 294 GLU A CB  1 
ATOM   1620 C  CG  . GLU A 1 294 ? 121.822 122.012 103.951 1.00 111.33 ? 294 GLU A CG  1 
ATOM   1621 C  CD  . GLU A 1 294 ? 122.858 122.999 104.431 1.00 112.99 ? 294 GLU A CD  1 
ATOM   1622 O  OE1 . GLU A 1 294 ? 123.573 123.558 103.579 1.00 110.62 ? 294 GLU A OE1 1 
ATOM   1623 O  OE2 . GLU A 1 294 ? 122.967 123.216 105.654 1.00 114.78 ? 294 GLU A OE2 1 
ATOM   1624 N  N   . GLY A 1 295 ? 117.607 122.250 105.926 1.00 105.23 ? 295 GLY A N   1 
ATOM   1625 C  CA  . GLY A 1 295 ? 116.250 122.022 105.483 1.00 105.99 ? 295 GLY A CA  1 
ATOM   1626 C  C   . GLY A 1 295 ? 115.725 123.143 104.609 1.00 108.56 ? 295 GLY A C   1 
ATOM   1627 O  O   . GLY A 1 295 ? 116.320 124.211 104.497 1.00 108.04 ? 295 GLY A O   1 
ATOM   1628 N  N   . THR A 1 296 ? 114.584 122.878 103.987 1.00 104.50 ? 296 THR A N   1 
ATOM   1629 C  CA  . THR A 1 296 ? 113.953 123.869 103.132 1.00 98.95  ? 296 THR A CA  1 
ATOM   1630 C  C   . THR A 1 296 ? 113.529 125.077 103.964 1.00 106.93 ? 296 THR A C   1 
ATOM   1631 O  O   . THR A 1 296 ? 113.059 124.914 105.095 1.00 117.23 ? 296 THR A O   1 
ATOM   1632 C  CB  . THR A 1 296 ? 112.740 123.259 102.429 1.00 105.17 ? 296 THR A CB  1 
ATOM   1633 O  OG1 . THR A 1 296 ? 113.127 122.041 101.785 1.00 117.66 ? 296 THR A OG1 1 
ATOM   1634 C  CG2 . THR A 1 296 ? 112.178 124.204 101.391 1.00 114.13 ? 296 THR A CG2 1 
ATOM   1635 N  N   . PRO A 1 297 ? 113.699 126.296 103.453 1.00 109.40 ? 297 PRO A N   1 
ATOM   1636 C  CA  . PRO A 1 297 ? 113.214 127.471 104.185 1.00 109.09 ? 297 PRO A CA  1 
ATOM   1637 C  C   . PRO A 1 297 ? 111.709 127.408 104.397 1.00 114.37 ? 297 PRO A C   1 
ATOM   1638 O  O   . PRO A 1 297 ? 110.968 126.843 103.591 1.00 118.61 ? 297 PRO A O   1 
ATOM   1639 C  CB  . PRO A 1 297 ? 113.606 128.645 103.280 1.00 107.54 ? 297 PRO A CB  1 
ATOM   1640 C  CG  . PRO A 1 297 ? 113.989 128.039 101.974 1.00 106.66 ? 297 PRO A CG  1 
ATOM   1641 C  CD  . PRO A 1 297 ? 114.490 126.677 102.275 1.00 110.00 ? 297 PRO A CD  1 
ATOM   1642 N  N   . ARG A 1 298 ? 111.265 127.991 105.513 1.00 124.21 ? 298 ARG A N   1 
ATOM   1643 C  CA  . ARG A 1 298 ? 109.867 127.867 105.916 1.00 123.47 ? 298 ARG A CA  1 
ATOM   1644 C  C   . ARG A 1 298 ? 108.924 128.460 104.877 1.00 124.28 ? 298 ARG A C   1 
ATOM   1645 O  O   . ARG A 1 298 ? 107.898 127.857 104.544 1.00 124.12 ? 298 ARG A O   1 
ATOM   1646 C  CB  . ARG A 1 298 ? 109.654 128.541 107.269 1.00 123.81 ? 298 ARG A CB  1 
ATOM   1647 C  CG  . ARG A 1 298 ? 110.313 127.822 108.428 1.00 125.68 ? 298 ARG A CG  1 
ATOM   1648 C  CD  . ARG A 1 298 ? 109.361 126.821 109.058 1.00 129.16 ? 298 ARG A CD  1 
ATOM   1649 N  NE  . ARG A 1 298 ? 110.038 125.939 110.000 1.00 132.77 ? 298 ARG A NE  1 
ATOM   1650 C  CZ  . ARG A 1 298 ? 109.501 124.840 110.513 1.00 133.82 ? 298 ARG A CZ  1 
ATOM   1651 N  NH1 . ARG A 1 298 ? 108.275 124.458 110.197 1.00 127.41 ? 298 ARG A NH1 1 
ATOM   1652 N  NH2 . ARG A 1 298 ? 110.214 124.106 111.362 1.00 132.82 ? 298 ARG A NH2 1 
ATOM   1653 N  N   . ASN A 1 299 ? 109.249 129.643 104.356 1.00 123.71 ? 299 ASN A N   1 
ATOM   1654 C  CA  . ASN A 1 299 ? 108.345 130.303 103.422 1.00 127.02 ? 299 ASN A CA  1 
ATOM   1655 C  C   . ASN A 1 299 ? 108.368 129.634 102.055 1.00 128.90 ? 299 ASN A C   1 
ATOM   1656 O  O   . ASN A 1 299 ? 107.319 129.466 101.423 1.00 128.69 ? 299 ASN A O   1 
ATOM   1657 C  CB  . ASN A 1 299 ? 108.710 131.780 103.300 1.00 130.34 ? 299 ASN A CB  1 
ATOM   1658 C  CG  . ASN A 1 299 ? 109.290 132.342 104.579 1.00 132.11 ? 299 ASN A CG  1 
ATOM   1659 O  OD1 . ASN A 1 299 ? 110.405 132.862 104.593 1.00 130.67 ? 299 ASN A OD1 1 
ATOM   1660 N  ND2 . ASN A 1 299 ? 108.532 132.245 105.665 1.00 129.81 ? 299 ASN A ND2 1 
ATOM   1661 N  N   . VAL A 1 300 ? 109.546 129.246 101.584 1.00 123.78 ? 300 VAL A N   1 
ATOM   1662 C  CA  . VAL A 1 300 ? 109.690 128.690 100.245 1.00 121.90 ? 300 VAL A CA  1 
ATOM   1663 C  C   . VAL A 1 300 ? 109.261 127.230 100.255 1.00 119.22 ? 300 VAL A C   1 
ATOM   1664 O  O   . VAL A 1 300 ? 109.702 126.446 101.103 1.00 121.08 ? 300 VAL A O   1 
ATOM   1665 C  CB  . VAL A 1 300 ? 111.135 128.841 99.750  1.00 123.20 ? 300 VAL A CB  1 
ATOM   1666 C  CG1 . VAL A 1 300 ? 111.210 128.573 98.266  1.00 119.87 ? 300 VAL A CG1 1 
ATOM   1667 C  CG2 . VAL A 1 300 ? 111.653 130.232 100.067 1.00 121.79 ? 300 VAL A CG2 1 
ATOM   1668 N  N   . GLY A 1 301 ? 108.401 126.862 99.313  1.00 105.45 ? 301 GLY A N   1 
ATOM   1669 C  CA  . GLY A 1 301 ? 107.910 125.505 99.201  1.00 107.46 ? 301 GLY A CA  1 
ATOM   1670 C  C   . GLY A 1 301 ? 108.585 124.745 98.075  1.00 112.21 ? 301 GLY A C   1 
ATOM   1671 O  O   . GLY A 1 301 ? 108.962 125.319 97.058  1.00 119.02 ? 301 GLY A O   1 
ATOM   1672 N  N   . PHE A 1 302 ? 108.730 123.435 98.272  1.00 105.32 ? 302 PHE A N   1 
ATOM   1673 C  CA  . PHE A 1 302 ? 109.357 122.591 97.261  1.00 96.86  ? 302 PHE A CA  1 
ATOM   1674 C  C   . PHE A 1 302 ? 108.525 122.545 95.987  1.00 101.52 ? 302 PHE A C   1 
ATOM   1675 O  O   . PHE A 1 302 ? 109.049 122.732 94.882  1.00 114.95 ? 302 PHE A O   1 
ATOM   1676 C  CB  . PHE A 1 302 ? 109.560 121.185 97.825  1.00 107.40 ? 302 PHE A CB  1 
ATOM   1677 C  CG  . PHE A 1 302 ? 110.357 120.277 96.937  1.00 107.74 ? 302 PHE A CG  1 
ATOM   1678 C  CD1 . PHE A 1 302 ? 109.735 119.521 95.961  1.00 105.79 ? 302 PHE A CD1 1 
ATOM   1679 C  CD2 . PHE A 1 302 ? 111.723 120.160 97.094  1.00 107.07 ? 302 PHE A CD2 1 
ATOM   1680 C  CE1 . PHE A 1 302 ? 110.461 118.684 95.150  1.00 100.78 ? 302 PHE A CE1 1 
ATOM   1681 C  CE2 . PHE A 1 302 ? 112.453 119.322 96.285  1.00 108.23 ? 302 PHE A CE2 1 
ATOM   1682 C  CZ  . PHE A 1 302 ? 111.821 118.583 95.313  1.00 107.17 ? 302 PHE A CZ  1 
ATOM   1683 N  N   . GLU A 1 303 ? 107.226 122.287 96.122  1.00 113.36 ? 303 GLU A N   1 
ATOM   1684 C  CA  . GLU A 1 303 ? 106.360 122.174 94.950  1.00 113.92 ? 303 GLU A CA  1 
ATOM   1685 C  C   . GLU A 1 303 ? 106.251 123.467 94.153  1.00 122.07 ? 303 GLU A C   1 
ATOM   1686 O  O   . GLU A 1 303 ? 106.291 123.399 92.913  1.00 121.88 ? 303 GLU A O   1 
ATOM   1687 C  CB  . GLU A 1 303 ? 104.980 121.670 95.378  1.00 119.28 ? 303 GLU A CB  1 
ATOM   1688 C  CG  . GLU A 1 303 ? 104.933 120.189 95.671  1.00 123.62 ? 303 GLU A CG  1 
ATOM   1689 C  CD  . GLU A 1 303 ? 105.224 119.886 97.125  1.00 131.73 ? 303 GLU A CD  1 
ATOM   1690 O  OE1 . GLU A 1 303 ? 105.526 120.832 97.882  1.00 130.26 ? 303 GLU A OE1 1 
ATOM   1691 O  OE2 . GLU A 1 303 ? 105.143 118.703 97.513  1.00 129.86 ? 303 GLU A OE2 1 
ATOM   1692 N  N   . PRO A 1 304 ? 106.062 124.648 94.759  1.00 118.27 ? 304 PRO A N   1 
ATOM   1693 C  CA  . PRO A 1 304 ? 106.043 125.870 93.937  1.00 110.83 ? 304 PRO A CA  1 
ATOM   1694 C  C   . PRO A 1 304 ? 107.319 126.083 93.146  1.00 113.91 ? 304 PRO A C   1 
ATOM   1695 O  O   . PRO A 1 304 ? 107.256 126.459 91.970  1.00 119.82 ? 304 PRO A O   1 
ATOM   1696 C  CB  . PRO A 1 304 ? 105.824 126.980 94.972  1.00 110.50 ? 304 PRO A CB  1 
ATOM   1697 C  CG  . PRO A 1 304 ? 105.135 126.314 96.090  1.00 113.21 ? 304 PRO A CG  1 
ATOM   1698 C  CD  . PRO A 1 304 ? 105.720 124.942 96.162  1.00 115.52 ? 304 PRO A CD  1 
ATOM   1699 N  N   . VAL A 1 305 ? 108.480 125.827 93.750  1.00 101.55 ? 305 VAL A N   1 
ATOM   1700 C  CA  . VAL A 1 305 ? 109.738 126.005 93.035  1.00 97.79  ? 305 VAL A CA  1 
ATOM   1701 C  C   . VAL A 1 305 ? 109.862 124.990 91.908  1.00 100.81 ? 305 VAL A C   1 
ATOM   1702 O  O   . VAL A 1 305 ? 110.294 125.324 90.799  1.00 113.10 ? 305 VAL A O   1 
ATOM   1703 C  CB  . VAL A 1 305 ? 110.925 125.916 94.008  1.00 96.26  ? 305 VAL A CB  1 
ATOM   1704 C  CG1 . VAL A 1 305 ? 112.232 126.046 93.254  1.00 98.73  ? 305 VAL A CG1 1 
ATOM   1705 C  CG2 . VAL A 1 305 ? 110.818 126.990 95.060  1.00 100.36 ? 305 VAL A CG2 1 
ATOM   1706 N  N   . ARG A 1 306 ? 109.494 123.735 92.172  1.00 109.52 ? 306 ARG A N   1 
ATOM   1707 C  CA  . ARG A 1 306 ? 109.577 122.717 91.131  1.00 110.52 ? 306 ARG A CA  1 
ATOM   1708 C  C   . ARG A 1 306 ? 108.648 123.040 89.970  1.00 114.90 ? 306 ARG A C   1 
ATOM   1709 O  O   . ARG A 1 306 ? 109.014 122.855 88.804  1.00 123.33 ? 306 ARG A O   1 
ATOM   1710 C  CB  . ARG A 1 306 ? 109.256 121.341 91.707  1.00 113.93 ? 306 ARG A CB  1 
ATOM   1711 C  CG  . ARG A 1 306 ? 109.504 120.204 90.734  1.00 114.13 ? 306 ARG A CG  1 
ATOM   1712 C  CD  . ARG A 1 306 ? 108.994 118.883 91.275  1.00 114.33 ? 306 ARG A CD  1 
ATOM   1713 N  NE  . ARG A 1 306 ? 107.715 119.029 91.958  1.00 125.09 ? 306 ARG A NE  1 
ATOM   1714 C  CZ  . ARG A 1 306 ? 106.543 119.113 91.344  1.00 126.47 ? 306 ARG A CZ  1 
ATOM   1715 N  NH1 . ARG A 1 306 ? 106.448 119.071 90.026  1.00 121.00 ? 306 ARG A NH1 1 
ATOM   1716 N  NH2 . ARG A 1 306 ? 105.437 119.243 92.072  1.00 122.00 ? 306 ARG A NH2 1 
ATOM   1717 N  N   . ASP A 1 307 ? 107.441 123.523 90.266  1.00 115.28 ? 307 ASP A N   1 
ATOM   1718 C  CA  . ASP A 1 307 ? 106.507 123.872 89.201  1.00 114.87 ? 307 ASP A CA  1 
ATOM   1719 C  C   . ASP A 1 307 ? 106.980 125.095 88.429  1.00 116.53 ? 307 ASP A C   1 
ATOM   1720 O  O   . ASP A 1 307 ? 106.779 125.181 87.212  1.00 119.20 ? 307 ASP A O   1 
ATOM   1721 C  CB  . ASP A 1 307 ? 105.114 124.104 89.781  1.00 118.57 ? 307 ASP A CB  1 
ATOM   1722 C  CG  . ASP A 1 307 ? 104.558 122.873 90.460  1.00 128.23 ? 307 ASP A CG  1 
ATOM   1723 O  OD1 . ASP A 1 307 ? 105.248 121.833 90.461  1.00 129.77 ? 307 ASP A OD1 1 
ATOM   1724 O  OD2 . ASP A 1 307 ? 103.431 122.942 90.993  1.00 124.89 ? 307 ASP A OD2 1 
ATOM   1725 N  N   . THR A 1 308 ? 107.598 126.057 89.116  1.00 109.84 ? 308 THR A N   1 
ATOM   1726 C  CA  . THR A 1 308 ? 108.176 127.200 88.420  1.00 105.37 ? 308 THR A CA  1 
ATOM   1727 C  C   . THR A 1 308 ? 109.282 126.760 87.474  1.00 111.11 ? 308 THR A C   1 
ATOM   1728 O  O   . THR A 1 308 ? 109.353 127.222 86.329  1.00 114.53 ? 308 THR A O   1 
ATOM   1729 C  CB  . THR A 1 308 ? 108.714 128.210 89.432  1.00 102.12 ? 308 THR A CB  1 
ATOM   1730 O  OG1 . THR A 1 308 ? 107.633 128.715 90.223  1.00 114.41 ? 308 THR A OG1 1 
ATOM   1731 C  CG2 . THR A 1 308 ? 109.393 129.362 88.723  1.00 108.99 ? 308 THR A CG2 1 
ATOM   1732 N  N   . LEU A 1 309 ? 110.151 125.860 87.933  1.00 107.43 ? 309 LEU A N   1 
ATOM   1733 C  CA  . LEU A 1 309 ? 111.245 125.394 87.090  1.00 96.50  ? 309 LEU A CA  1 
ATOM   1734 C  C   . LEU A 1 309 ? 110.731 124.582 85.911  1.00 106.50 ? 309 LEU A C   1 
ATOM   1735 O  O   . LEU A 1 309 ? 111.244 124.707 84.794  1.00 118.29 ? 309 LEU A O   1 
ATOM   1736 C  CB  . LEU A 1 309 ? 112.231 124.575 87.917  1.00 94.64  ? 309 LEU A CB  1 
ATOM   1737 C  CG  . LEU A 1 309 ? 113.073 125.394 88.892  1.00 97.13  ? 309 LEU A CG  1 
ATOM   1738 C  CD1 . LEU A 1 309 ? 114.021 124.500 89.658  1.00 104.58 ? 309 LEU A CD1 1 
ATOM   1739 C  CD2 . LEU A 1 309 ? 113.832 126.470 88.149  1.00 96.80  ? 309 LEU A CD2 1 
ATOM   1740 N  N   . LEU A 1 310 ? 109.719 123.744 86.133  1.00 104.76 ? 310 LEU A N   1 
ATOM   1741 C  CA  . LEU A 1 310 ? 109.195 122.910 85.061  1.00 103.87 ? 310 LEU A CA  1 
ATOM   1742 C  C   . LEU A 1 310 ? 108.350 123.691 84.067  1.00 108.92 ? 310 LEU A C   1 
ATOM   1743 O  O   . LEU A 1 310 ? 108.116 123.203 82.957  1.00 110.27 ? 310 LEU A O   1 
ATOM   1744 C  CB  . LEU A 1 310 ? 108.373 121.763 85.644  1.00 104.69 ? 310 LEU A CB  1 
ATOM   1745 C  CG  . LEU A 1 310 ? 109.178 120.556 86.119  1.00 106.43 ? 310 LEU A CG  1 
ATOM   1746 C  CD1 . LEU A 1 310 ? 108.430 119.817 87.208  1.00 111.53 ? 310 LEU A CD1 1 
ATOM   1747 C  CD2 . LEU A 1 310 ? 109.479 119.634 84.957  1.00 107.62 ? 310 LEU A CD2 1 
ATOM   1748 N  N   . SER A 1 311 ? 107.887 124.884 84.435  1.00 116.20 ? 311 SER A N   1 
ATOM   1749 C  CA  . SER A 1 311 ? 107.081 125.697 83.536  1.00 116.82 ? 311 SER A CA  1 
ATOM   1750 C  C   . SER A 1 311 ? 107.915 126.472 82.527  1.00 119.44 ? 311 SER A C   1 
ATOM   1751 O  O   . SER A 1 311 ? 107.345 127.059 81.602  1.00 118.53 ? 311 SER A O   1 
ATOM   1752 C  CB  . SER A 1 311 ? 106.222 126.673 84.339  1.00 115.19 ? 311 SER A CB  1 
ATOM   1753 O  OG  . SER A 1 311 ? 107.034 127.572 85.072  1.00 121.78 ? 311 SER A OG  1 
ATOM   1754 N  N   . VAL A 1 312 ? 109.231 126.494 82.684  1.00 119.55 ? 312 VAL A N   1 
ATOM   1755 C  CA  . VAL A 1 312 ? 110.094 127.196 81.728  1.00 113.20 ? 312 VAL A CA  1 
ATOM   1756 C  C   . VAL A 1 312 ? 110.028 126.482 80.383  1.00 117.44 ? 312 VAL A C   1 
ATOM   1757 O  O   . VAL A 1 312 ? 110.192 125.251 80.331  1.00 120.57 ? 312 VAL A O   1 
ATOM   1758 C  CB  . VAL A 1 312 ? 111.528 127.250 82.251  1.00 108.28 ? 312 VAL A CB  1 
ATOM   1759 C  CG1 . VAL A 1 312 ? 112.441 127.896 81.229  1.00 110.36 ? 312 VAL A CG1 1 
ATOM   1760 C  CG2 . VAL A 1 312 ? 111.580 128.000 83.566  1.00 111.07 ? 312 VAL A CG2 1 
ATOM   1761 N  N   . PRO A 1 313 ? 109.785 127.190 79.282  1.00 122.09 ? 313 PRO A N   1 
ATOM   1762 C  CA  . PRO A 1 313 ? 109.692 126.516 77.981  1.00 123.30 ? 313 PRO A CA  1 
ATOM   1763 C  C   . PRO A 1 313 ? 111.004 125.869 77.569  1.00 127.12 ? 313 PRO A C   1 
ATOM   1764 O  O   . PRO A 1 313 ? 111.992 126.559 77.304  1.00 126.45 ? 313 PRO A O   1 
ATOM   1765 C  CB  . PRO A 1 313 ? 109.296 127.649 77.025  1.00 117.56 ? 313 PRO A CB  1 
ATOM   1766 C  CG  . PRO A 1 313 ? 109.719 128.897 77.714  1.00 120.42 ? 313 PRO A CG  1 
ATOM   1767 C  CD  . PRO A 1 313 ? 109.551 128.638 79.176  1.00 119.53 ? 313 PRO A CD  1 
ATOM   1768 N  N   . GLY A 1 314 ? 111.018 124.536 77.510  1.00 123.62 ? 314 GLY A N   1 
ATOM   1769 C  CA  . GLY A 1 314 ? 112.202 123.764 77.172  1.00 118.88 ? 314 GLY A CA  1 
ATOM   1770 C  C   . GLY A 1 314 ? 112.575 122.737 78.223  1.00 119.58 ? 314 GLY A C   1 
ATOM   1771 O  O   . GLY A 1 314 ? 113.131 121.688 77.885  1.00 123.12 ? 314 GLY A O   1 
ATOM   1772 N  N   . VAL A 1 315 ? 112.276 123.018 79.491  1.00 107.73 ? 315 VAL A N   1 
ATOM   1773 C  CA  . VAL A 1 315 ? 112.601 122.086 80.561  1.00 108.31 ? 315 VAL A CA  1 
ATOM   1774 C  C   . VAL A 1 315 ? 111.658 120.893 80.507  1.00 113.47 ? 315 VAL A C   1 
ATOM   1775 O  O   . VAL A 1 315 ? 110.435 121.047 80.389  1.00 119.41 ? 315 VAL A O   1 
ATOM   1776 C  CB  . VAL A 1 315 ? 112.527 122.792 81.925  1.00 105.76 ? 315 VAL A CB  1 
ATOM   1777 C  CG1 . VAL A 1 315 ? 112.880 121.829 83.038  1.00 107.47 ? 315 VAL A CG1 1 
ATOM   1778 C  CG2 . VAL A 1 315 ? 113.450 123.989 81.946  1.00 109.02 ? 315 VAL A CG2 1 
ATOM   1779 N  N   . ARG A 1 316 ? 112.224 119.690 80.592  1.00 121.52 ? 316 ARG A N   1 
ATOM   1780 C  CA  . ARG A 1 316 ? 111.442 118.464 80.550  1.00 118.82 ? 316 ARG A CA  1 
ATOM   1781 C  C   . ARG A 1 316 ? 111.468 117.685 81.854  1.00 121.36 ? 316 ARG A C   1 
ATOM   1782 O  O   . ARG A 1 316 ? 110.610 116.819 82.054  1.00 129.57 ? 316 ARG A O   1 
ATOM   1783 C  CB  . ARG A 1 316 ? 111.932 117.557 79.416  1.00 115.90 ? 316 ARG A CB  1 
ATOM   1784 C  CG  . ARG A 1 316 ? 111.729 118.138 78.035  1.00 124.36 ? 316 ARG A CG  1 
ATOM   1785 C  CD  . ARG A 1 316 ? 110.351 117.806 77.494  1.00 124.41 ? 316 ARG A CD  1 
ATOM   1786 N  NE  . ARG A 1 316 ? 109.969 116.424 77.760  1.00 126.70 ? 316 ARG A NE  1 
ATOM   1787 C  CZ  . ARG A 1 316 ? 110.366 115.385 77.039  1.00 128.63 ? 316 ARG A CZ  1 
ATOM   1788 N  NH1 . ARG A 1 316 ? 111.173 115.530 76.002  1.00 128.19 ? 316 ARG A NH1 1 
ATOM   1789 N  NH2 . ARG A 1 316 ? 109.939 114.168 77.366  1.00 124.42 ? 316 ARG A NH2 1 
ATOM   1790 N  N   . ALA A 1 317 ? 112.414 117.964 82.746  1.00 107.45 ? 317 ALA A N   1 
ATOM   1791 C  CA  . ALA A 1 317 ? 112.506 117.239 84.006  1.00 110.83 ? 317 ALA A CA  1 
ATOM   1792 C  C   . ALA A 1 317 ? 113.347 118.012 85.010  1.00 111.26 ? 317 ALA A C   1 
ATOM   1793 O  O   . ALA A 1 317 ? 113.912 119.058 84.681  1.00 115.96 ? 317 ALA A O   1 
ATOM   1794 C  CB  . ALA A 1 317 ? 113.093 115.846 83.786  1.00 114.20 ? 317 ALA A CB  1 
ATOM   1795 N  N   . THR A 1 318 ? 113.432 117.506 86.235  1.00 107.34 ? 318 THR A N   1 
ATOM   1796 C  CA  . THR A 1 318 ? 114.195 118.162 87.283  1.00 107.81 ? 318 THR A CA  1 
ATOM   1797 C  C   . THR A 1 318 ? 114.628 117.112 88.292  1.00 113.92 ? 318 THR A C   1 
ATOM   1798 O  O   . THR A 1 318 ? 113.846 116.236 88.667  1.00 119.85 ? 318 THR A O   1 
ATOM   1799 C  CB  . THR A 1 318 ? 113.377 119.258 87.977  1.00 112.40 ? 318 THR A CB  1 
ATOM   1800 O  OG1 . THR A 1 318 ? 112.923 120.208 87.006  1.00 119.72 ? 318 THR A OG1 1 
ATOM   1801 C  CG2 . THR A 1 318 ? 114.211 119.975 89.018  1.00 113.44 ? 318 THR A CG2 1 
ATOM   1802 N  N   . HIS A 1 319 ? 115.882 117.204 88.722  1.00 109.71 ? 319 HIS A N   1 
ATOM   1803 C  CA  . HIS A 1 319 ? 116.386 116.328 89.765  1.00 106.71 ? 319 HIS A CA  1 
ATOM   1804 C  C   . HIS A 1 319 ? 117.438 117.080 90.561  1.00 104.89 ? 319 HIS A C   1 
ATOM   1805 O  O   . HIS A 1 319 ? 117.972 118.098 90.118  1.00 113.66 ? 319 HIS A O   1 
ATOM   1806 C  CB  . HIS A 1 319 ? 116.952 115.025 89.194  1.00 111.17 ? 319 HIS A CB  1 
ATOM   1807 C  CG  . HIS A 1 319 ? 117.945 115.221 88.093  1.00 109.94 ? 319 HIS A CG  1 
ATOM   1808 N  ND1 . HIS A 1 319 ? 117.576 115.367 86.774  1.00 108.77 ? 319 HIS A ND1 1 
ATOM   1809 C  CD2 . HIS A 1 319 ? 119.298 115.269 88.112  1.00 112.33 ? 319 HIS A CD2 1 
ATOM   1810 C  CE1 . HIS A 1 319 ? 118.657 115.508 86.030  1.00 112.25 ? 319 HIS A CE1 1 
ATOM   1811 N  NE2 . HIS A 1 319 ? 119.715 115.450 86.817  1.00 116.48 ? 319 HIS A NE2 1 
ATOM   1812 N  N   . GLU A 1 320 ? 117.720 116.566 91.755  1.00 111.42 ? 320 GLU A N   1 
ATOM   1813 C  CA  . GLU A 1 320 ? 118.690 117.171 92.663  1.00 112.28 ? 320 GLU A CA  1 
ATOM   1814 C  C   . GLU A 1 320 ? 118.344 118.628 92.948  1.00 113.90 ? 320 GLU A C   1 
ATOM   1815 O  O   . GLU A 1 320 ? 119.212 119.499 92.991  1.00 121.54 ? 320 GLU A O   1 
ATOM   1816 C  CB  . GLU A 1 320 ? 120.108 117.045 92.112  1.00 115.36 ? 320 GLU A CB  1 
ATOM   1817 C  CG  . GLU A 1 320 ? 120.550 115.618 91.882  1.00 122.28 ? 320 GLU A CG  1 
ATOM   1818 C  CD  . GLU A 1 320 ? 122.031 115.430 92.113  1.00 129.73 ? 320 GLU A CD  1 
ATOM   1819 O  OE1 . GLU A 1 320 ? 122.577 116.082 93.027  1.00 126.38 ? 320 GLU A OE1 1 
ATOM   1820 O  OE2 . GLU A 1 320 ? 122.651 114.633 91.379  1.00 132.37 ? 320 GLU A OE2 1 
ATOM   1821 N  N   . LEU A 1 321 ? 117.057 118.894 93.140  1.00 92.01  ? 321 LEU A N   1 
ATOM   1822 C  CA  . LEU A 1 321 ? 116.595 120.229 93.499  1.00 91.68  ? 321 LEU A CA  1 
ATOM   1823 C  C   . LEU A 1 321 ? 116.830 120.433 94.989  1.00 89.68  ? 321 LEU A C   1 
ATOM   1824 O  O   . LEU A 1 321 ? 116.185 119.789 95.820  1.00 102.19 ? 321 LEU A O   1 
ATOM   1825 C  CB  . LEU A 1 321 ? 115.122 120.398 93.141  1.00 91.96  ? 321 LEU A CB  1 
ATOM   1826 C  CG  . LEU A 1 321 ? 114.394 121.601 93.737  1.00 92.14  ? 321 LEU A CG  1 
ATOM   1827 C  CD1 . LEU A 1 321 ? 114.990 122.891 93.221  1.00 98.07  ? 321 LEU A CD1 1 
ATOM   1828 C  CD2 . LEU A 1 321 ? 112.919 121.535 93.410  1.00 91.84  ? 321 LEU A CD2 1 
ATOM   1829 N  N   . HIS A 1 322 ? 117.758 121.320 95.329  1.00 85.21  ? 322 HIS A N   1 
ATOM   1830 C  CA  . HIS A 1 322 ? 118.128 121.584 96.711  1.00 86.27  ? 322 HIS A CA  1 
ATOM   1831 C  C   . HIS A 1 322 ? 117.740 123.006 97.079  1.00 92.17  ? 322 HIS A C   1 
ATOM   1832 O  O   . HIS A 1 322 ? 118.104 123.953 96.377  1.00 102.54 ? 322 HIS A O   1 
ATOM   1833 C  CB  . HIS A 1 322 ? 119.626 121.380 96.927  1.00 92.78  ? 322 HIS A CB  1 
ATOM   1834 C  CG  . HIS A 1 322 ? 120.074 119.964 96.758  1.00 97.28  ? 322 HIS A CG  1 
ATOM   1835 N  ND1 . HIS A 1 322 ? 119.519 118.920 97.463  1.00 100.23 ? 322 HIS A ND1 1 
ATOM   1836 C  CD2 . HIS A 1 322 ? 121.023 119.420 95.963  1.00 98.82  ? 322 HIS A CD2 1 
ATOM   1837 C  CE1 . HIS A 1 322 ? 120.107 117.792 97.109  1.00 106.31 ? 322 HIS A CE1 1 
ATOM   1838 N  NE2 . HIS A 1 322 ? 121.023 118.068 96.200  1.00 107.64 ? 322 HIS A NE2 1 
ATOM   1839 N  N   . LEU A 1 323 ? 117.000 123.149 98.173  1.00 91.18  ? 323 LEU A N   1 
ATOM   1840 C  CA  . LEU A 1 323 ? 116.624 124.447 98.708  1.00 85.12  ? 323 LEU A CA  1 
ATOM   1841 C  C   . LEU A 1 323 ? 117.025 124.501 100.171 1.00 87.39  ? 323 LEU A C   1 
ATOM   1842 O  O   . LEU A 1 323 ? 116.649 123.621 100.950 1.00 100.74 ? 323 LEU A O   1 
ATOM   1843 C  CB  . LEU A 1 323 ? 115.123 124.699 98.567  1.00 84.73  ? 323 LEU A CB  1 
ATOM   1844 C  CG  . LEU A 1 323 ? 114.511 124.452 97.192  1.00 91.00  ? 323 LEU A CG  1 
ATOM   1845 C  CD1 . LEU A 1 323 ? 113.002 124.421 97.291  1.00 94.10  ? 323 LEU A CD1 1 
ATOM   1846 C  CD2 . LEU A 1 323 ? 114.958 125.518 96.217  1.00 96.62  ? 323 LEU A CD2 1 
ATOM   1847 N  N   . TRP A 1 324 ? 117.789 125.523 100.539 1.00 74.81  ? 324 TRP A N   1 
ATOM   1848 C  CA  . TRP A 1 324 ? 118.179 125.709 101.926 1.00 81.70  ? 324 TRP A CA  1 
ATOM   1849 C  C   . TRP A 1 324 ? 118.485 127.179 102.152 1.00 88.55  ? 324 TRP A C   1 
ATOM   1850 O  O   . TRP A 1 324 ? 118.644 127.953 101.207 1.00 98.36  ? 324 TRP A O   1 
ATOM   1851 C  CB  . TRP A 1 324 ? 119.375 124.827 102.305 1.00 88.48  ? 324 TRP A CB  1 
ATOM   1852 C  CG  . TRP A 1 324 ? 120.689 125.281 101.764 1.00 87.78  ? 324 TRP A CG  1 
ATOM   1853 C  CD1 . TRP A 1 324 ? 121.681 125.912 102.448 1.00 89.05  ? 324 TRP A CD1 1 
ATOM   1854 C  CD2 . TRP A 1 324 ? 121.166 125.117 100.426 1.00 85.32  ? 324 TRP A CD2 1 
ATOM   1855 N  NE1 . TRP A 1 324 ? 122.744 126.160 101.620 1.00 88.23  ? 324 TRP A NE1 1 
ATOM   1856 C  CE2 . TRP A 1 324 ? 122.452 125.682 100.371 1.00 85.71  ? 324 TRP A CE2 1 
ATOM   1857 C  CE3 . TRP A 1 324 ? 120.629 124.552 99.269  1.00 90.94  ? 324 TRP A CE3 1 
ATOM   1858 C  CZ2 . TRP A 1 324 ? 123.207 125.697 99.207  1.00 93.96  ? 324 TRP A CZ2 1 
ATOM   1859 C  CZ3 . TRP A 1 324 ? 121.380 124.570 98.115  1.00 85.89  ? 324 TRP A CZ3 1 
ATOM   1860 C  CH2 . TRP A 1 324 ? 122.653 125.139 98.091  1.00 92.78  ? 324 TRP A CH2 1 
ATOM   1861 N  N   . ALA A 1 325 ? 118.556 127.557 103.423 1.00 91.66  ? 325 ALA A N   1 
ATOM   1862 C  CA  . ALA A 1 325 ? 118.693 128.948 103.818 1.00 91.20  ? 325 ALA A CA  1 
ATOM   1863 C  C   . ALA A 1 325 ? 119.915 129.120 104.703 1.00 97.42  ? 325 ALA A C   1 
ATOM   1864 O  O   . ALA A 1 325 ? 120.105 128.362 105.658 1.00 103.64 ? 325 ALA A O   1 
ATOM   1865 C  CB  . ALA A 1 325 ? 117.442 129.428 104.554 1.00 96.26  ? 325 ALA A CB  1 
ATOM   1866 N  N   . LEU A 1 326 ? 120.746 130.111 104.378 1.00 96.63  ? 326 LEU A N   1 
ATOM   1867 C  CA  . LEU A 1 326 ? 121.812 130.497 105.294 1.00 93.98  ? 326 LEU A CA  1 
ATOM   1868 C  C   . LEU A 1 326 ? 121.239 131.107 106.564 1.00 99.23  ? 326 LEU A C   1 
ATOM   1869 O  O   . LEU A 1 326 ? 121.731 130.841 107.665 1.00 109.13 ? 326 LEU A O   1 
ATOM   1870 C  CB  . LEU A 1 326 ? 122.764 131.476 104.615 1.00 98.55  ? 326 LEU A CB  1 
ATOM   1871 C  CG  . LEU A 1 326 ? 123.694 130.904 103.549 1.00 100.69 ? 326 LEU A CG  1 
ATOM   1872 C  CD1 . LEU A 1 326 ? 124.802 131.890 103.257 1.00 103.19 ? 326 LEU A CD1 1 
ATOM   1873 C  CD2 . LEU A 1 326 ? 124.266 129.575 103.991 1.00 100.97 ? 326 LEU A CD2 1 
ATOM   1874 N  N   . THR A 1 327 ? 120.204 131.926 106.431 1.00 107.27 ? 327 THR A N   1 
ATOM   1875 C  CA  . THR A 1 327 ? 119.515 132.498 107.576 1.00 106.28 ? 327 THR A CA  1 
ATOM   1876 C  C   . THR A 1 327 ? 118.051 132.688 107.199 1.00 111.09 ? 327 THR A C   1 
ATOM   1877 O  O   . THR A 1 327 ? 117.585 132.175 106.179 1.00 121.17 ? 327 THR A O   1 
ATOM   1878 C  CB  . THR A 1 327 ? 120.178 133.807 108.018 1.00 106.58 ? 327 THR A CB  1 
ATOM   1879 O  OG1 . THR A 1 327 ? 119.436 134.370 109.105 1.00 116.16 ? 327 THR A OG1 1 
ATOM   1880 C  CG2 . THR A 1 327 ? 120.218 134.798 106.875 1.00 106.73 ? 327 THR A CG2 1 
ATOM   1881 N  N   . LEU A 1 328 ? 117.321 133.433 108.028 1.00 114.36 ? 328 LEU A N   1 
ATOM   1882 C  CA  . LEU A 1 328 ? 115.897 133.630 107.791 1.00 116.42 ? 328 LEU A CA  1 
ATOM   1883 C  C   . LEU A 1 328 ? 115.616 134.397 106.508 1.00 116.89 ? 328 LEU A C   1 
ATOM   1884 O  O   . LEU A 1 328 ? 114.522 134.268 105.951 1.00 121.26 ? 328 LEU A O   1 
ATOM   1885 C  CB  . LEU A 1 328 ? 115.269 134.363 108.973 1.00 120.26 ? 328 LEU A CB  1 
ATOM   1886 C  CG  . LEU A 1 328 ? 115.231 133.612 110.300 1.00 121.79 ? 328 LEU A CG  1 
ATOM   1887 C  CD1 . LEU A 1 328 ? 114.570 134.472 111.350 1.00 123.33 ? 328 LEU A CD1 1 
ATOM   1888 C  CD2 . LEU A 1 328 ? 114.486 132.302 110.146 1.00 115.30 ? 328 LEU A CD2 1 
ATOM   1889 N  N   . THR A 1 329 ? 116.569 135.195 106.030 1.00 113.77 ? 329 THR A N   1 
ATOM   1890 C  CA  . THR A 1 329 ? 116.362 136.018 104.849 1.00 118.08 ? 329 THR A CA  1 
ATOM   1891 C  C   . THR A 1 329 ? 117.252 135.639 103.674 1.00 123.23 ? 329 THR A C   1 
ATOM   1892 O  O   . THR A 1 329 ? 116.996 136.100 102.557 1.00 123.55 ? 329 THR A O   1 
ATOM   1893 C  CB  . THR A 1 329 ? 116.589 137.498 105.188 1.00 124.70 ? 329 THR A CB  1 
ATOM   1894 O  OG1 . THR A 1 329 ? 117.991 137.788 105.147 1.00 130.35 ? 329 THR A OG1 1 
ATOM   1895 C  CG2 . THR A 1 329 ? 116.057 137.814 106.574 1.00 118.56 ? 329 THR A CG2 1 
ATOM   1896 N  N   . TYR A 1 330 ? 118.279 134.824 103.888 1.00 110.66 ? 330 TYR A N   1 
ATOM   1897 C  CA  . TYR A 1 330 ? 119.211 134.431 102.837 1.00 103.60 ? 330 TYR A CA  1 
ATOM   1898 C  C   . TYR A 1 330 ? 118.880 133.008 102.404 1.00 102.96 ? 330 TYR A C   1 
ATOM   1899 O  O   . TYR A 1 330 ? 119.105 132.057 103.158 1.00 107.05 ? 330 TYR A O   1 
ATOM   1900 C  CB  . TYR A 1 330 ? 120.651 134.535 103.331 1.00 102.05 ? 330 TYR A CB  1 
ATOM   1901 C  CG  . TYR A 1 330 ? 121.683 134.668 102.239 1.00 101.55 ? 330 TYR A CG  1 
ATOM   1902 C  CD1 . TYR A 1 330 ? 122.120 133.559 101.533 1.00 103.76 ? 330 TYR A CD1 1 
ATOM   1903 C  CD2 . TYR A 1 330 ? 122.231 135.900 101.924 1.00 101.15 ? 330 TYR A CD2 1 
ATOM   1904 C  CE1 . TYR A 1 330 ? 123.066 133.673 100.541 1.00 108.28 ? 330 TYR A CE1 1 
ATOM   1905 C  CE2 . TYR A 1 330 ? 123.178 136.024 100.933 1.00 100.51 ? 330 TYR A CE2 1 
ATOM   1906 C  CZ  . TYR A 1 330 ? 123.592 134.908 100.245 1.00 107.20 ? 330 TYR A CZ  1 
ATOM   1907 O  OH  . TYR A 1 330 ? 124.537 135.027 99.254  1.00 112.13 ? 330 TYR A OH  1 
ATOM   1908 N  N   . HIS A 1 331 ? 118.356 132.862 101.193 1.00 100.70 ? 331 HIS A N   1 
ATOM   1909 C  CA  . HIS A 1 331 ? 117.942 131.573 100.662 1.00 98.97  ? 331 HIS A CA  1 
ATOM   1910 C  C   . HIS A 1 331 ? 118.805 131.197 99.467  1.00 103.03 ? 331 HIS A C   1 
ATOM   1911 O  O   . HIS A 1 331 ? 119.123 132.044 98.628  1.00 104.41 ? 331 HIS A O   1 
ATOM   1912 C  CB  . HIS A 1 331 ? 116.471 131.598 100.245 1.00 100.37 ? 331 HIS A CB  1 
ATOM   1913 C  CG  . HIS A 1 331 ? 115.538 131.997 101.343 1.00 103.11 ? 331 HIS A CG  1 
ATOM   1914 N  ND1 . HIS A 1 331 ? 115.760 131.672 102.663 1.00 105.47 ? 331 HIS A ND1 1 
ATOM   1915 C  CD2 . HIS A 1 331 ? 114.380 132.696 101.317 1.00 102.05 ? 331 HIS A CD2 1 
ATOM   1916 C  CE1 . HIS A 1 331 ? 114.777 132.151 103.403 1.00 105.25 ? 331 HIS A CE1 1 
ATOM   1917 N  NE2 . HIS A 1 331 ? 113.927 132.778 102.611 1.00 108.25 ? 331 HIS A NE2 1 
ATOM   1918 N  N   . VAL A 1 332 ? 119.181 129.924 99.395  1.00 91.06  ? 332 VAL A N   1 
ATOM   1919 C  CA  . VAL A 1 332 ? 119.994 129.399 98.307  1.00 86.85  ? 332 VAL A CA  1 
ATOM   1920 C  C   . VAL A 1 332 ? 119.208 128.303 97.605  1.00 85.27  ? 332 VAL A C   1 
ATOM   1921 O  O   . VAL A 1 332 ? 118.390 127.612 98.218  1.00 99.91  ? 332 VAL A O   1 
ATOM   1922 C  CB  . VAL A 1 332 ? 121.349 128.861 98.812  1.00 94.32  ? 332 VAL A CB  1 
ATOM   1923 C  CG1 . VAL A 1 332 ? 122.328 128.727 97.665  1.00 97.39  ? 332 VAL A CG1 1 
ATOM   1924 C  CG2 . VAL A 1 332 ? 121.909 129.762 99.892  1.00 92.68  ? 332 VAL A CG2 1 
ATOM   1925 N  N   . ALA A 1 333 ? 119.457 128.146 96.307  1.00 86.43  ? 333 ALA A N   1 
ATOM   1926 C  CA  . ALA A 1 333 ? 118.763 127.134 95.527  1.00 91.20  ? 333 ALA A CA  1 
ATOM   1927 C  C   . ALA A 1 333 ? 119.720 126.521 94.518  1.00 99.49  ? 333 ALA A C   1 
ATOM   1928 O  O   . ALA A 1 333 ? 120.632 127.180 94.016  1.00 104.73 ? 333 ALA A O   1 
ATOM   1929 C  CB  . ALA A 1 333 ? 117.543 127.716 94.811  1.00 97.44  ? 333 ALA A CB  1 
ATOM   1930 N  N   . SER A 1 334 ? 119.496 125.243 94.228  1.00 99.74  ? 334 SER A N   1 
ATOM   1931 C  CA  . SER A 1 334 ? 120.234 124.535 93.192  1.00 90.75  ? 334 SER A CA  1 
ATOM   1932 C  C   . SER A 1 334 ? 119.306 123.497 92.584  1.00 93.93  ? 334 SER A C   1 
ATOM   1933 O  O   . SER A 1 334 ? 118.382 123.009 93.235  1.00 108.66 ? 334 SER A O   1 
ATOM   1934 C  CB  . SER A 1 334 ? 121.499 123.875 93.743  1.00 96.28  ? 334 SER A CB  1 
ATOM   1935 O  OG  . SER A 1 334 ? 122.182 124.736 94.632  1.00 110.30 ? 334 SER A OG  1 
ATOM   1936 N  N   . ALA A 1 335 ? 119.566 123.160 91.325  1.00 86.80  ? 335 ALA A N   1 
ATOM   1937 C  CA  . ALA A 1 335 ? 118.750 122.176 90.631  1.00 88.24  ? 335 ALA A CA  1 
ATOM   1938 C  C   . ALA A 1 335 ? 119.471 121.753 89.363  1.00 99.86  ? 335 ALA A C   1 
ATOM   1939 O  O   . ALA A 1 335 ? 120.322 122.477 88.841  1.00 113.63 ? 335 ALA A O   1 
ATOM   1940 C  CB  . ALA A 1 335 ? 117.364 122.723 90.288  1.00 92.83  ? 335 ALA A CB  1 
ATOM   1941 N  N   . HIS A 1 336 ? 119.118 120.569 88.877  1.00 100.00 ? 336 HIS A N   1 
ATOM   1942 C  CA  . HIS A 1 336 ? 119.574 120.070 87.588  1.00 95.69  ? 336 HIS A CA  1 
ATOM   1943 C  C   . HIS A 1 336 ? 118.373 120.046 86.656  1.00 98.60  ? 336 HIS A C   1 
ATOM   1944 O  O   . HIS A 1 336 ? 117.372 119.387 86.951  1.00 110.34 ? 336 HIS A O   1 
ATOM   1945 C  CB  . HIS A 1 336 ? 120.182 118.674 87.713  1.00 107.64 ? 336 HIS A CB  1 
ATOM   1946 C  CG  . HIS A 1 336 ? 121.382 118.604 88.606  1.00 103.34 ? 336 HIS A CG  1 
ATOM   1947 N  ND1 . HIS A 1 336 ? 122.366 117.653 88.452  1.00 101.62 ? 336 HIS A ND1 1 
ATOM   1948 C  CD2 . HIS A 1 336 ? 121.752 119.358 89.667  1.00 106.63 ? 336 HIS A CD2 1 
ATOM   1949 C  CE1 . HIS A 1 336 ? 123.293 117.827 89.376  1.00 101.01 ? 336 HIS A CE1 1 
ATOM   1950 N  NE2 . HIS A 1 336 ? 122.944 118.855 90.126  1.00 105.28 ? 336 HIS A NE2 1 
ATOM   1951 N  N   . LEU A 1 337 ? 118.467 120.761 85.543  1.00 98.24  ? 337 LEU A N   1 
ATOM   1952 C  CA  . LEU A 1 337 ? 117.367 120.880 84.596  1.00 97.89  ? 337 LEU A CA  1 
ATOM   1953 C  C   . LEU A 1 337 ? 117.682 120.050 83.363  1.00 100.70 ? 337 LEU A C   1 
ATOM   1954 O  O   . LEU A 1 337 ? 118.716 120.256 82.721  1.00 114.60 ? 337 LEU A O   1 
ATOM   1955 C  CB  . LEU A 1 337 ? 117.130 122.338 84.210  1.00 101.18 ? 337 LEU A CB  1 
ATOM   1956 C  CG  . LEU A 1 337 ? 116.947 123.335 85.351  1.00 103.56 ? 337 LEU A CG  1 
ATOM   1957 C  CD1 . LEU A 1 337 ? 116.636 124.709 84.798  1.00 101.11 ? 337 LEU A CD1 1 
ATOM   1958 C  CD2 . LEU A 1 337 ? 115.850 122.875 86.284  1.00 109.51 ? 337 LEU A CD2 1 
ATOM   1959 N  N   . ALA A 1 338 ? 116.793 119.121 83.033  1.00 100.87 ? 338 ALA A N   1 
ATOM   1960 C  CA  . ALA A 1 338 ? 116.916 118.307 81.832  1.00 102.83 ? 338 ALA A CA  1 
ATOM   1961 C  C   . ALA A 1 338 ? 116.058 118.943 80.747  1.00 107.91 ? 338 ALA A C   1 
ATOM   1962 O  O   . ALA A 1 338 ? 114.829 118.841 80.781  1.00 123.38 ? 338 ALA A O   1 
ATOM   1963 C  CB  . ALA A 1 338 ? 116.492 116.866 82.101  1.00 109.12 ? 338 ALA A CB  1 
ATOM   1964 N  N   . ILE A 1 339 ? 116.703 119.592 79.788  1.00 110.70 ? 339 ILE A N   1 
ATOM   1965 C  CA  . ILE A 1 339 ? 116.008 120.356 78.771  1.00 114.67 ? 339 ILE A CA  1 
ATOM   1966 C  C   . ILE A 1 339 ? 115.868 119.515 77.512  1.00 117.87 ? 339 ILE A C   1 
ATOM   1967 O  O   . ILE A 1 339 ? 116.532 118.492 77.332  1.00 122.93 ? 339 ILE A O   1 
ATOM   1968 C  CB  . ILE A 1 339 ? 116.728 121.685 78.466  1.00 110.14 ? 339 ILE A CB  1 
ATOM   1969 C  CG1 . ILE A 1 339 ? 118.033 121.420 77.718  1.00 112.83 ? 339 ILE A CG1 1 
ATOM   1970 C  CG2 . ILE A 1 339 ? 116.993 122.446 79.746  1.00 113.28 ? 339 ILE A CG2 1 
ATOM   1971 C  CD1 . ILE A 1 339 ? 118.617 122.642 77.062  1.00 118.13 ? 339 ILE A CD1 1 
ATOM   1972 N  N   . ASP A 1 340 ? 114.983 119.956 76.625  1.00 133.44 ? 340 ASP A N   1 
ATOM   1973 C  CA  . ASP A 1 340 ? 114.781 119.275 75.358  1.00 131.95 ? 340 ASP A CA  1 
ATOM   1974 C  C   . ASP A 1 340 ? 115.999 119.447 74.457  1.00 134.51 ? 340 ASP A C   1 
ATOM   1975 O  O   . ASP A 1 340 ? 116.809 120.363 74.624  1.00 138.24 ? 340 ASP A O   1 
ATOM   1976 C  CB  . ASP A 1 340 ? 113.537 119.810 74.652  1.00 133.17 ? 340 ASP A CB  1 
ATOM   1977 C  CG  . ASP A 1 340 ? 112.377 118.842 74.704  1.00 138.79 ? 340 ASP A CG  1 
ATOM   1978 O  OD1 . ASP A 1 340 ? 112.623 117.618 74.703  1.00 139.23 ? 340 ASP A OD1 1 
ATOM   1979 O  OD2 . ASP A 1 340 ? 111.218 119.304 74.743  1.00 138.90 ? 340 ASP A OD2 1 
ATOM   1980 N  N   . SER A 1 341 ? 116.124 118.539 73.488  1.00 135.38 ? 341 SER A N   1 
ATOM   1981 C  CA  . SER A 1 341 ? 117.217 118.634 72.527  1.00 136.25 ? 341 SER A CA  1 
ATOM   1982 C  C   . SER A 1 341 ? 117.114 119.911 71.705  1.00 136.47 ? 341 SER A C   1 
ATOM   1983 O  O   . SER A 1 341 ? 118.125 120.572 71.440  1.00 135.80 ? 341 SER A O   1 
ATOM   1984 C  CB  . SER A 1 341 ? 117.224 117.408 71.617  1.00 135.89 ? 341 SER A CB  1 
ATOM   1985 O  OG  . SER A 1 341 ? 116.170 117.474 70.673  1.00 137.36 ? 341 SER A OG  1 
ATOM   1986 N  N   . THR A 1 342 ? 115.903 120.275 71.291  1.00 143.01 ? 342 THR A N   1 
ATOM   1987 C  CA  . THR A 1 342 ? 115.684 121.494 70.513  1.00 143.92 ? 342 THR A CA  1 
ATOM   1988 C  C   . THR A 1 342 ? 115.370 122.672 71.437  1.00 143.44 ? 342 THR A C   1 
ATOM   1989 O  O   . THR A 1 342 ? 114.319 123.306 71.361  1.00 143.77 ? 342 THR A O   1 
ATOM   1990 C  CB  . THR A 1 342 ? 114.571 121.278 69.497  1.00 145.29 ? 342 THR A CB  1 
ATOM   1991 O  OG1 . THR A 1 342 ? 113.303 121.520 70.119  1.00 148.19 ? 342 THR A OG1 1 
ATOM   1992 C  CG2 . THR A 1 342 ? 114.605 119.854 68.967  1.00 143.15 ? 342 THR A CG2 1 
ATOM   1993 N  N   . ALA A 1 343 ? 116.320 122.959 72.323  1.00 140.15 ? 343 ALA A N   1 
ATOM   1994 C  CA  . ALA A 1 343 ? 116.200 124.068 73.255  1.00 140.32 ? 343 ALA A CA  1 
ATOM   1995 C  C   . ALA A 1 343 ? 117.540 124.782 73.352  1.00 142.48 ? 343 ALA A C   1 
ATOM   1996 O  O   . ALA A 1 343 ? 118.595 124.210 73.072  1.00 143.86 ? 343 ALA A O   1 
ATOM   1997 C  CB  . ALA A 1 343 ? 115.744 123.599 74.641  1.00 138.97 ? 343 ALA A CB  1 
ATOM   1998 N  N   . ASP A 1 344 ? 117.485 126.050 73.750  1.00 140.28 ? 344 ASP A N   1 
ATOM   1999 C  CA  . ASP A 1 344 ? 118.684 126.862 73.862  1.00 138.90 ? 344 ASP A CA  1 
ATOM   2000 C  C   . ASP A 1 344 ? 119.059 126.916 75.333  1.00 139.29 ? 344 ASP A C   1 
ATOM   2001 O  O   . ASP A 1 344 ? 118.299 127.482 76.132  1.00 140.39 ? 344 ASP A O   1 
ATOM   2002 C  CB  . ASP A 1 344 ? 118.428 128.265 73.295  1.00 138.75 ? 344 ASP A CB  1 
ATOM   2003 C  CG  . ASP A 1 344 ? 119.494 129.300 73.673  1.00 143.38 ? 344 ASP A CG  1 
ATOM   2004 O  OD1 . ASP A 1 344 ? 119.753 130.174 72.821  1.00 144.36 ? 344 ASP A OD1 1 
ATOM   2005 O  OD2 . ASP A 1 344 ? 120.048 129.300 74.788  1.00 142.70 ? 344 ASP A OD2 1 
ATOM   2006 N  N   . PRO A 1 345 ? 120.190 126.336 75.741  1.00 123.56 ? 345 PRO A N   1 
ATOM   2007 C  CA  . PRO A 1 345 ? 120.529 126.329 77.173  1.00 122.45 ? 345 PRO A CA  1 
ATOM   2008 C  C   . PRO A 1 345 ? 120.660 127.714 77.780  1.00 121.76 ? 345 PRO A C   1 
ATOM   2009 O  O   . PRO A 1 345 ? 120.288 127.909 78.943  1.00 125.50 ? 345 PRO A O   1 
ATOM   2010 C  CB  . PRO A 1 345 ? 121.860 125.565 77.210  1.00 121.06 ? 345 PRO A CB  1 
ATOM   2011 C  CG  . PRO A 1 345 ? 121.888 124.774 75.948  1.00 118.73 ? 345 PRO A CG  1 
ATOM   2012 C  CD  . PRO A 1 345 ? 121.180 125.608 74.933  1.00 119.43 ? 345 PRO A CD  1 
ATOM   2013 N  N   . GLU A 1 346 ? 121.180 128.686 77.030  1.00 131.68 ? 346 GLU A N   1 
ATOM   2014 C  CA  . GLU A 1 346 ? 121.345 130.029 77.576  1.00 132.96 ? 346 GLU A CA  1 
ATOM   2015 C  C   . GLU A 1 346 ? 119.997 130.672 77.870  1.00 132.49 ? 346 GLU A C   1 
ATOM   2016 O  O   . GLU A 1 346 ? 119.801 131.270 78.934  1.00 131.56 ? 346 GLU A O   1 
ATOM   2017 C  CB  . GLU A 1 346 ? 122.154 130.894 76.610  1.00 132.57 ? 346 GLU A CB  1 
ATOM   2018 C  CG  . GLU A 1 346 ? 123.633 130.566 76.578  1.00 137.33 ? 346 GLU A CG  1 
ATOM   2019 C  CD  . GLU A 1 346 ? 124.184 130.246 77.951  1.00 141.46 ? 346 GLU A CD  1 
ATOM   2020 O  OE1 . GLU A 1 346 ? 124.241 131.164 78.796  1.00 138.44 ? 346 GLU A OE1 1 
ATOM   2021 O  OE2 . GLU A 1 346 ? 124.557 129.077 78.186  1.00 138.64 ? 346 GLU A OE2 1 
ATOM   2022 N  N   . ALA A 1 347 ? 119.052 130.559 76.933  1.00 124.85 ? 347 ALA A N   1 
ATOM   2023 C  CA  . ALA A 1 347 ? 117.730 131.140 77.142  1.00 121.25 ? 347 ALA A CA  1 
ATOM   2024 C  C   . ALA A 1 347 ? 117.011 130.470 78.303  1.00 123.56 ? 347 ALA A C   1 
ATOM   2025 O  O   . ALA A 1 347 ? 116.385 131.145 79.129  1.00 127.46 ? 347 ALA A O   1 
ATOM   2026 C  CB  . ALA A 1 347 ? 116.902 131.032 75.863  1.00 117.75 ? 347 ALA A CB  1 
ATOM   2027 N  N   . VAL A 1 348 ? 117.090 129.141 78.382  1.00 112.68 ? 348 VAL A N   1 
ATOM   2028 C  CA  . VAL A 1 348 ? 116.458 128.418 79.480  1.00 108.75 ? 348 VAL A CA  1 
ATOM   2029 C  C   . VAL A 1 348 ? 117.054 128.850 80.810  1.00 111.06 ? 348 VAL A C   1 
ATOM   2030 O  O   . VAL A 1 348 ? 116.330 129.106 81.780  1.00 116.76 ? 348 VAL A O   1 
ATOM   2031 C  CB  . VAL A 1 348 ? 116.595 126.900 79.267  1.00 107.05 ? 348 VAL A CB  1 
ATOM   2032 C  CG1 . VAL A 1 348 ? 116.277 126.156 80.547  1.00 107.79 ? 348 VAL A CG1 1 
ATOM   2033 C  CG2 . VAL A 1 348 ? 115.690 126.442 78.143  1.00 116.50 ? 348 VAL A CG2 1 
ATOM   2034 N  N   . LEU A 1 349 ? 118.382 128.946 80.875  1.00 111.97 ? 349 LEU A N   1 
ATOM   2035 C  CA  . LEU A 1 349 ? 119.042 129.338 82.114  1.00 108.14 ? 349 LEU A CA  1 
ATOM   2036 C  C   . LEU A 1 349 ? 118.645 130.748 82.527  1.00 110.62 ? 349 LEU A C   1 
ATOM   2037 O  O   . LEU A 1 349 ? 118.333 131.001 83.697  1.00 116.09 ? 349 LEU A O   1 
ATOM   2038 C  CB  . LEU A 1 349 ? 120.555 129.230 81.943  1.00 107.54 ? 349 LEU A CB  1 
ATOM   2039 C  CG  . LEU A 1 349 ? 121.415 129.648 83.130  1.00 112.71 ? 349 LEU A CG  1 
ATOM   2040 C  CD1 . LEU A 1 349 ? 121.041 128.845 84.356  1.00 116.87 ? 349 LEU A CD1 1 
ATOM   2041 C  CD2 . LEU A 1 349 ? 122.877 129.462 82.789  1.00 111.14 ? 349 LEU A CD2 1 
ATOM   2042 N  N   . ALA A 1 350 ? 118.641 131.681 81.573  1.00 112.53 ? 350 ALA A N   1 
ATOM   2043 C  CA  . ALA A 1 350 ? 118.286 133.060 81.890  1.00 114.79 ? 350 ALA A CA  1 
ATOM   2044 C  C   . ALA A 1 350 ? 116.846 133.160 82.371  1.00 118.65 ? 350 ALA A C   1 
ATOM   2045 O  O   . ALA A 1 350 ? 116.558 133.824 83.375  1.00 121.99 ? 350 ALA A O   1 
ATOM   2046 C  CB  . ALA A 1 350 ? 118.509 133.950 80.668  1.00 115.83 ? 350 ALA A CB  1 
ATOM   2047 N  N   . GLU A 1 351 ? 115.925 132.493 81.671  1.00 115.74 ? 351 GLU A N   1 
ATOM   2048 C  CA  . GLU A 1 351 ? 114.520 132.557 82.054  1.00 113.61 ? 351 GLU A CA  1 
ATOM   2049 C  C   . GLU A 1 351 ? 114.290 131.933 83.422  1.00 117.88 ? 351 GLU A C   1 
ATOM   2050 O  O   . GLU A 1 351 ? 113.558 132.489 84.248  1.00 121.06 ? 351 GLU A O   1 
ATOM   2051 C  CB  . GLU A 1 351 ? 113.660 131.868 80.997  1.00 113.32 ? 351 GLU A CB  1 
ATOM   2052 C  CG  . GLU A 1 351 ? 112.244 131.572 81.449  1.00 121.82 ? 351 GLU A CG  1 
ATOM   2053 C  CD  . GLU A 1 351 ? 111.359 132.801 81.441  1.00 127.08 ? 351 GLU A CD  1 
ATOM   2054 O  OE1 . GLU A 1 351 ? 111.742 133.808 80.811  1.00 127.14 ? 351 GLU A OE1 1 
ATOM   2055 O  OE2 . GLU A 1 351 ? 110.279 132.759 82.066  1.00 123.07 ? 351 GLU A OE2 1 
ATOM   2056 N  N   . ALA A 1 352 ? 114.909 130.780 83.686  1.00 108.56 ? 352 ALA A N   1 
ATOM   2057 C  CA  . ALA A 1 352 ? 114.730 130.129 84.978  1.00 103.91 ? 352 ALA A CA  1 
ATOM   2058 C  C   . ALA A 1 352 ? 115.304 130.973 86.106  1.00 109.12 ? 352 ALA A C   1 
ATOM   2059 O  O   . ALA A 1 352 ? 114.686 131.100 87.170  1.00 117.98 ? 352 ALA A O   1 
ATOM   2060 C  CB  . ALA A 1 352 ? 115.374 128.745 84.960  1.00 103.56 ? 352 ALA A CB  1 
ATOM   2061 N  N   . SER A 1 353 ? 116.485 131.559 85.897  1.00 112.65 ? 353 SER A N   1 
ATOM   2062 C  CA  . SER A 1 353 ? 117.074 132.406 86.927  1.00 109.65 ? 353 SER A CA  1 
ATOM   2063 C  C   . SER A 1 353 ? 116.203 133.623 87.200  1.00 112.24 ? 353 SER A C   1 
ATOM   2064 O  O   . SER A 1 353 ? 115.980 133.988 88.361  1.00 116.67 ? 353 SER A O   1 
ATOM   2065 C  CB  . SER A 1 353 ? 118.478 132.835 86.509  1.00 115.52 ? 353 SER A CB  1 
ATOM   2066 O  OG  . SER A 1 353 ? 119.173 131.763 85.900  1.00 120.61 ? 353 SER A OG  1 
ATOM   2067 N  N   . SER A 1 354 ? 115.694 134.260 86.141  1.00 116.52 ? 354 SER A N   1 
ATOM   2068 C  CA  . SER A 1 354 ? 114.832 135.421 86.329  1.00 115.88 ? 354 SER A CA  1 
ATOM   2069 C  C   . SER A 1 354 ? 113.557 135.045 87.068  1.00 118.32 ? 354 SER A C   1 
ATOM   2070 O  O   . SER A 1 354 ? 113.125 135.762 87.977  1.00 120.68 ? 354 SER A O   1 
ATOM   2071 C  CB  . SER A 1 354 ? 114.501 136.051 84.978  1.00 114.47 ? 354 SER A CB  1 
ATOM   2072 O  OG  . SER A 1 354 ? 115.681 136.411 84.284  1.00 123.19 ? 354 SER A OG  1 
ATOM   2073 N  N   . ARG A 1 355 ? 112.944 133.919 86.695  1.00 116.30 ? 355 ARG A N   1 
ATOM   2074 C  CA  . ARG A 1 355 ? 111.719 133.491 87.358  1.00 109.20 ? 355 ARG A CA  1 
ATOM   2075 C  C   . ARG A 1 355 ? 111.960 133.206 88.831  1.00 106.83 ? 355 ARG A C   1 
ATOM   2076 O  O   . ARG A 1 355 ? 111.175 133.625 89.687  1.00 118.63 ? 355 ARG A O   1 
ATOM   2077 C  CB  . ARG A 1 355 ? 111.150 132.256 86.665  1.00 107.76 ? 355 ARG A CB  1 
ATOM   2078 C  CG  . ARG A 1 355 ? 110.347 132.566 85.423  1.00 113.24 ? 355 ARG A CG  1 
ATOM   2079 C  CD  . ARG A 1 355 ? 109.511 131.377 85.003  1.00 110.94 ? 355 ARG A CD  1 
ATOM   2080 N  NE  . ARG A 1 355 ? 108.969 131.552 83.663  1.00 117.27 ? 355 ARG A NE  1 
ATOM   2081 C  CZ  . ARG A 1 355 ? 108.136 130.704 83.077  1.00 122.84 ? 355 ARG A CZ  1 
ATOM   2082 N  NH1 . ARG A 1 355 ? 107.725 129.607 83.689  1.00 122.55 ? 355 ARG A NH1 1 
ATOM   2083 N  NH2 . ARG A 1 355 ? 107.706 130.964 81.846  1.00 120.82 ? 355 ARG A NH2 1 
ATOM   2084 N  N   . LEU A 1 356 ? 113.043 132.495 89.148  1.00 105.34 ? 356 LEU A N   1 
ATOM   2085 C  CA  . LEU A 1 356 ? 113.331 132.190 90.543  1.00 111.30 ? 356 LEU A CA  1 
ATOM   2086 C  C   . LEU A 1 356 ? 113.594 133.459 91.340  1.00 113.36 ? 356 LEU A C   1 
ATOM   2087 O  O   . LEU A 1 356 ? 113.070 133.622 92.448  1.00 118.30 ? 356 LEU A O   1 
ATOM   2088 C  CB  . LEU A 1 356 ? 114.521 131.237 90.640  1.00 111.49 ? 356 LEU A CB  1 
ATOM   2089 C  CG  . LEU A 1 356 ? 114.227 129.768 90.340  1.00 108.19 ? 356 LEU A CG  1 
ATOM   2090 C  CD1 . LEU A 1 356 ? 115.350 128.891 90.846  1.00 110.69 ? 356 LEU A CD1 1 
ATOM   2091 C  CD2 . LEU A 1 356 ? 112.906 129.350 90.953  1.00 111.70 ? 356 LEU A CD2 1 
ATOM   2092 N  N   . TYR A 1 357 ? 114.387 134.380 90.786  1.00 121.62 ? 357 TYR A N   1 
ATOM   2093 C  CA  . TYR A 1 357 ? 114.692 135.611 91.505  1.00 121.27 ? 357 TYR A CA  1 
ATOM   2094 C  C   . TYR A 1 357 ? 113.438 136.446 91.732  1.00 123.72 ? 357 TYR A C   1 
ATOM   2095 O  O   . TYR A 1 357 ? 113.245 137.003 92.818  1.00 126.00 ? 357 TYR A O   1 
ATOM   2096 C  CB  . TYR A 1 357 ? 115.739 136.420 90.743  1.00 120.08 ? 357 TYR A CB  1 
ATOM   2097 C  CG  . TYR A 1 357 ? 115.984 137.792 91.326  1.00 125.56 ? 357 TYR A CG  1 
ATOM   2098 C  CD1 . TYR A 1 357 ? 116.204 137.961 92.686  1.00 124.40 ? 357 TYR A CD1 1 
ATOM   2099 C  CD2 . TYR A 1 357 ? 115.984 138.920 90.519  1.00 127.99 ? 357 TYR A CD2 1 
ATOM   2100 C  CE1 . TYR A 1 357 ? 116.425 139.212 93.224  1.00 124.80 ? 357 TYR A CE1 1 
ATOM   2101 C  CE2 . TYR A 1 357 ? 116.203 140.176 91.048  1.00 129.09 ? 357 TYR A CE2 1 
ATOM   2102 C  CZ  . TYR A 1 357 ? 116.423 140.316 92.401  1.00 129.59 ? 357 TYR A CZ  1 
ATOM   2103 O  OH  . TYR A 1 357 ? 116.642 141.565 92.932  1.00 125.79 ? 357 TYR A OH  1 
ATOM   2104 N  N   . SER A 1 358 ? 112.573 136.546 90.723  1.00 116.97 ? 358 SER A N   1 
ATOM   2105 C  CA  . SER A 1 358 ? 111.381 137.373 90.861  1.00 115.10 ? 358 SER A CA  1 
ATOM   2106 C  C   . SER A 1 358 ? 110.382 136.748 91.826  1.00 119.65 ? 358 SER A C   1 
ATOM   2107 O  O   . SER A 1 358 ? 109.845 137.431 92.705  1.00 121.92 ? 358 SER A O   1 
ATOM   2108 C  CB  . SER A 1 358 ? 110.740 137.597 89.493  1.00 117.29 ? 358 SER A CB  1 
ATOM   2109 O  OG  . SER A 1 358 ? 109.883 136.523 89.154  1.00 122.06 ? 358 SER A OG  1 
ATOM   2110 N  N   . ARG A 1 359 ? 110.117 135.449 91.682  1.00 114.64 ? 359 ARG A N   1 
ATOM   2111 C  CA  . ARG A 1 359 ? 109.076 134.812 92.478  1.00 106.77 ? 359 ARG A CA  1 
ATOM   2112 C  C   . ARG A 1 359 ? 109.508 134.581 93.920  1.00 112.33 ? 359 ARG A C   1 
ATOM   2113 O  O   . ARG A 1 359 ? 108.719 134.804 94.844  1.00 113.23 ? 359 ARG A O   1 
ATOM   2114 C  CB  . ARG A 1 359 ? 108.666 133.490 91.833  1.00 110.93 ? 359 ARG A CB  1 
ATOM   2115 C  CG  . ARG A 1 359 ? 107.169 133.261 91.784  1.00 116.33 ? 359 ARG A CG  1 
ATOM   2116 C  CD  . ARG A 1 359 ? 106.789 132.396 90.598  1.00 117.18 ? 359 ARG A CD  1 
ATOM   2117 N  NE  . ARG A 1 359 ? 107.103 133.043 89.330  1.00 122.55 ? 359 ARG A NE  1 
ATOM   2118 C  CZ  . ARG A 1 359 ? 106.815 132.537 88.139  1.00 123.55 ? 359 ARG A CZ  1 
ATOM   2119 N  NH1 . ARG A 1 359 ? 106.213 131.366 88.013  1.00 114.98 ? 359 ARG A NH1 1 
ATOM   2120 N  NH2 . ARG A 1 359 ? 107.141 133.222 87.048  1.00 122.66 ? 359 ARG A NH2 1 
ATOM   2121 N  N   . PHE A 1 360 ? 110.743 134.132 94.144  1.00 104.75 ? 360 PHE A N   1 
ATOM   2122 C  CA  . PHE A 1 360 ? 111.158 133.704 95.470  1.00 106.29 ? 360 PHE A CA  1 
ATOM   2123 C  C   . PHE A 1 360 ? 112.309 134.505 96.057  1.00 110.42 ? 360 PHE A C   1 
ATOM   2124 O  O   . PHE A 1 360 ? 112.578 134.369 97.256  1.00 109.68 ? 360 PHE A O   1 
ATOM   2125 C  CB  . PHE A 1 360 ? 111.541 132.217 95.451  1.00 108.63 ? 360 PHE A CB  1 
ATOM   2126 C  CG  . PHE A 1 360 ? 110.487 131.335 94.856  1.00 109.25 ? 360 PHE A CG  1 
ATOM   2127 C  CD1 . PHE A 1 360 ? 109.447 130.862 95.631  1.00 109.69 ? 360 PHE A CD1 1 
ATOM   2128 C  CD2 . PHE A 1 360 ? 110.529 130.987 93.520  1.00 104.93 ? 360 PHE A CD2 1 
ATOM   2129 C  CE1 . PHE A 1 360 ? 108.474 130.057 95.086  1.00 108.92 ? 360 PHE A CE1 1 
ATOM   2130 C  CE2 . PHE A 1 360 ? 109.559 130.184 92.971  1.00 104.04 ? 360 PHE A CE2 1 
ATOM   2131 C  CZ  . PHE A 1 360 ? 108.530 129.718 93.755  1.00 108.09 ? 360 PHE A CZ  1 
ATOM   2132 N  N   . GLY A 1 361 ? 112.989 135.328 95.267  1.00 117.91 ? 361 GLY A N   1 
ATOM   2133 C  CA  . GLY A 1 361 ? 114.047 136.165 95.793  1.00 118.75 ? 361 GLY A CA  1 
ATOM   2134 C  C   . GLY A 1 361 ? 115.214 135.391 96.368  1.00 115.56 ? 361 GLY A C   1 
ATOM   2135 O  O   . GLY A 1 361 ? 115.683 135.691 97.469  1.00 113.58 ? 361 GLY A O   1 
ATOM   2136 N  N   . PHE A 1 362 ? 115.684 134.385 95.640  1.00 114.27 ? 362 PHE A N   1 
ATOM   2137 C  CA  . PHE A 1 362 ? 116.834 133.617 96.091  1.00 110.03 ? 362 PHE A CA  1 
ATOM   2138 C  C   . PHE A 1 362 ? 118.097 134.458 95.976  1.00 111.58 ? 362 PHE A C   1 
ATOM   2139 O  O   . PHE A 1 362 ? 118.365 135.056 94.930  1.00 112.47 ? 362 PHE A O   1 
ATOM   2140 C  CB  . PHE A 1 362 ? 116.970 132.338 95.271  1.00 101.63 ? 362 PHE A CB  1 
ATOM   2141 C  CG  . PHE A 1 362 ? 115.978 131.280 95.637  1.00 103.53 ? 362 PHE A CG  1 
ATOM   2142 C  CD1 . PHE A 1 362 ? 115.929 130.777 96.922  1.00 102.22 ? 362 PHE A CD1 1 
ATOM   2143 C  CD2 . PHE A 1 362 ? 115.091 130.791 94.700  1.00 108.02 ? 362 PHE A CD2 1 
ATOM   2144 C  CE1 . PHE A 1 362 ? 115.018 129.806 97.263  1.00 98.65  ? 362 PHE A CE1 1 
ATOM   2145 C  CE2 . PHE A 1 362 ? 114.179 129.819 95.037  1.00 107.67 ? 362 PHE A CE2 1 
ATOM   2146 C  CZ  . PHE A 1 362 ? 114.143 129.327 96.320  1.00 101.14 ? 362 PHE A CZ  1 
ATOM   2147 N  N   . SER A 1 363 ? 118.874 134.506 97.058  1.00 104.85 ? 363 SER A N   1 
ATOM   2148 C  CA  . SER A 1 363 ? 120.120 135.261 97.034  1.00 101.30 ? 363 SER A CA  1 
ATOM   2149 C  C   . SER A 1 363 ? 121.142 134.609 96.114  1.00 106.28 ? 363 SER A C   1 
ATOM   2150 O  O   . SER A 1 363 ? 121.884 135.301 95.410  1.00 109.61 ? 363 SER A O   1 
ATOM   2151 C  CB  . SER A 1 363 ? 120.675 135.396 98.449  1.00 105.58 ? 363 SER A CB  1 
ATOM   2152 O  OG  . SER A 1 363 ? 119.686 135.893 99.332  1.00 113.95 ? 363 SER A OG  1 
ATOM   2153 N  N   . SER A 1 364 ? 121.196 133.281 96.108  1.00 111.47 ? 364 SER A N   1 
ATOM   2154 C  CA  . SER A 1 364 ? 122.089 132.530 95.241  1.00 109.09 ? 364 SER A CA  1 
ATOM   2155 C  C   . SER A 1 364 ? 121.294 131.448 94.530  1.00 110.12 ? 364 SER A C   1 
ATOM   2156 O  O   . SER A 1 364 ? 120.405 130.833 95.122  1.00 119.68 ? 364 SER A O   1 
ATOM   2157 C  CB  . SER A 1 364 ? 123.239 131.907 96.035  1.00 113.76 ? 364 SER A CB  1 
ATOM   2158 O  OG  . SER A 1 364 ? 124.166 131.268 95.176  1.00 117.26 ? 364 SER A OG  1 
ATOM   2159 N  N   . CYS A 1 365 ? 121.614 131.222 93.260  1.00 106.01 ? 365 CYS A N   1 
ATOM   2160 C  CA  . CYS A 1 365 ? 120.897 130.237 92.459  1.00 101.92 ? 365 CYS A CA  1 
ATOM   2161 C  C   . CYS A 1 365 ? 121.848 129.660 91.425  1.00 110.00 ? 365 CYS A C   1 
ATOM   2162 O  O   . CYS A 1 365 ? 122.380 130.400 90.593  1.00 115.79 ? 365 CYS A O   1 
ATOM   2163 C  CB  . CYS A 1 365 ? 119.682 130.867 91.780  1.00 105.45 ? 365 CYS A CB  1 
ATOM   2164 S  SG  . CYS A 1 365 ? 118.831 129.784 90.623  1.00 130.02 ? 365 CYS A SG  1 
ATOM   2165 N  N   . THR A 1 366 ? 122.055 128.347 91.473  1.00 96.21  ? 366 THR A N   1 
ATOM   2166 C  CA  . THR A 1 366 ? 122.908 127.641 90.526  1.00 94.97  ? 366 THR A CA  1 
ATOM   2167 C  C   . THR A 1 366 ? 122.094 126.535 89.875  1.00 96.61  ? 366 THR A C   1 
ATOM   2168 O  O   . THR A 1 366 ? 121.608 125.635 90.564  1.00 111.42 ? 366 THR A O   1 
ATOM   2169 C  CB  . THR A 1 366 ? 124.139 127.058 91.220  1.00 96.83  ? 366 THR A CB  1 
ATOM   2170 O  OG1 . THR A 1 366 ? 124.897 128.114 91.818  1.00 105.58 ? 366 THR A OG1 1 
ATOM   2171 C  CG2 . THR A 1 366 ? 125.011 126.324 90.223  1.00 93.90  ? 366 THR A CG2 1 
ATOM   2172 N  N   . LEU A 1 367 ? 121.950 126.599 88.557  1.00 90.90  ? 367 LEU A N   1 
ATOM   2173 C  CA  . LEU A 1 367 ? 121.163 125.631 87.809  1.00 88.52  ? 367 LEU A CA  1 
ATOM   2174 C  C   . LEU A 1 367 ? 122.048 124.934 86.790  1.00 92.66  ? 367 LEU A C   1 
ATOM   2175 O  O   . LEU A 1 367 ? 122.692 125.594 85.970  1.00 103.52 ? 367 LEU A O   1 
ATOM   2176 C  CB  . LEU A 1 367 ? 119.987 126.307 87.108  1.00 89.51  ? 367 LEU A CB  1 
ATOM   2177 C  CG  . LEU A 1 367 ? 119.092 127.166 87.997  1.00 90.38  ? 367 LEU A CG  1 
ATOM   2178 C  CD1 . LEU A 1 367 ? 118.200 128.034 87.146  1.00 98.49  ? 367 LEU A CD1 1 
ATOM   2179 C  CD2 . LEU A 1 367 ? 118.268 126.299 88.923  1.00 94.54  ? 367 LEU A CD2 1 
ATOM   2180 N  N   . GLN A 1 368 ? 122.071 123.608 86.836  1.00 93.67  ? 368 GLN A N   1 
ATOM   2181 C  CA  . GLN A 1 368 ? 122.840 122.803 85.897  1.00 91.97  ? 368 GLN A CA  1 
ATOM   2182 C  C   . GLN A 1 368 ? 121.909 122.356 84.780  1.00 97.68  ? 368 GLN A C   1 
ATOM   2183 O  O   . GLN A 1 368 ? 121.032 121.516 84.994  1.00 108.51 ? 368 GLN A O   1 
ATOM   2184 C  CB  . GLN A 1 368 ? 123.474 121.604 86.596  1.00 94.31  ? 368 GLN A CB  1 
ATOM   2185 C  CG  . GLN A 1 368 ? 124.154 120.642 85.651  1.00 97.46  ? 368 GLN A CG  1 
ATOM   2186 C  CD  . GLN A 1 368 ? 124.971 119.603 86.374  1.00 102.23 ? 368 GLN A CD  1 
ATOM   2187 O  OE1 . GLN A 1 368 ? 125.478 119.847 87.465  1.00 107.79 ? 368 GLN A OE1 1 
ATOM   2188 N  NE2 . GLN A 1 368 ? 125.101 118.430 85.773  1.00 108.50 ? 368 GLN A NE2 1 
ATOM   2189 N  N   . VAL A 1 369 ? 122.099 122.917 83.592  1.00 98.36  ? 369 VAL A N   1 
ATOM   2190 C  CA  . VAL A 1 369 ? 121.250 122.618 82.446  1.00 98.96  ? 369 VAL A CA  1 
ATOM   2191 C  C   . VAL A 1 369 ? 121.826 121.400 81.736  1.00 100.72 ? 369 VAL A C   1 
ATOM   2192 O  O   . VAL A 1 369 ? 122.844 121.492 81.046  1.00 111.35 ? 369 VAL A O   1 
ATOM   2193 C  CB  . VAL A 1 369 ? 121.143 123.819 81.501  1.00 99.12  ? 369 VAL A CB  1 
ATOM   2194 C  CG1 . VAL A 1 369 ? 120.447 123.419 80.220  1.00 101.49 ? 369 VAL A CG1 1 
ATOM   2195 C  CG2 . VAL A 1 369 ? 120.392 124.947 82.178  1.00 100.34 ? 369 VAL A CG2 1 
ATOM   2196 N  N   . GLU A 1 370 ? 121.176 120.255 81.911  1.00 109.27 ? 370 GLU A N   1 
ATOM   2197 C  CA  . GLU A 1 370 ? 121.573 119.013 81.275  1.00 109.12 ? 370 GLU A CA  1 
ATOM   2198 C  C   . GLU A 1 370 ? 120.722 118.780 80.031  1.00 113.84 ? 370 GLU A C   1 
ATOM   2199 O  O   . GLU A 1 370 ? 119.866 119.589 79.671  1.00 119.36 ? 370 GLU A O   1 
ATOM   2200 C  CB  . GLU A 1 370 ? 121.446 117.849 82.259  1.00 110.91 ? 370 GLU A CB  1 
ATOM   2201 C  CG  . GLU A 1 370 ? 122.523 117.819 83.324  1.00 110.30 ? 370 GLU A CG  1 
ATOM   2202 C  CD  . GLU A 1 370 ? 122.108 117.041 84.554  1.00 117.68 ? 370 GLU A CD  1 
ATOM   2203 O  OE1 . GLU A 1 370 ? 120.947 116.592 84.614  1.00 121.81 ? 370 GLU A OE1 1 
ATOM   2204 O  OE2 . GLU A 1 370 ? 122.949 116.867 85.459  1.00 124.96 ? 370 GLU A OE2 1 
ATOM   2205 N  N   . GLN A 1 371 ? 120.964 117.659 79.364  1.00 124.13 ? 371 GLN A N   1 
ATOM   2206 C  CA  . GLN A 1 371 ? 120.188 117.249 78.202  1.00 119.60 ? 371 GLN A CA  1 
ATOM   2207 C  C   . GLN A 1 371 ? 119.327 116.055 78.580  1.00 129.23 ? 371 GLN A C   1 
ATOM   2208 O  O   . GLN A 1 371 ? 119.821 115.096 79.182  1.00 134.56 ? 371 GLN A O   1 
ATOM   2209 C  CB  . GLN A 1 371 ? 121.098 116.900 77.025  1.00 119.14 ? 371 GLN A CB  1 
ATOM   2210 C  CG  . GLN A 1 371 ? 121.696 118.108 76.340  1.00 122.70 ? 371 GLN A CG  1 
ATOM   2211 C  CD  . GLN A 1 371 ? 120.836 118.610 75.202  1.00 126.18 ? 371 GLN A CD  1 
ATOM   2212 O  OE1 . GLN A 1 371 ? 120.154 117.832 74.538  1.00 128.64 ? 371 GLN A OE1 1 
ATOM   2213 N  NE2 . GLN A 1 371 ? 120.862 119.916 74.972  1.00 124.01 ? 371 GLN A NE2 1 
ATOM   2214 N  N   . TYR A 1 372 ? 118.046 116.114 78.232  1.00 140.52 ? 372 TYR A N   1 
ATOM   2215 C  CA  . TYR A 1 372 ? 117.094 115.090 78.656  1.00 140.54 ? 372 TYR A CA  1 
ATOM   2216 C  C   . TYR A 1 372 ? 117.285 113.847 77.801  1.00 141.70 ? 372 TYR A C   1 
ATOM   2217 O  O   . TYR A 1 372 ? 116.688 113.697 76.734  1.00 140.54 ? 372 TYR A O   1 
ATOM   2218 C  CB  . TYR A 1 372 ? 115.664 115.598 78.560  1.00 143.96 ? 372 TYR A CB  1 
ATOM   2219 C  CG  . TYR A 1 372 ? 114.647 114.542 78.913  1.00 145.16 ? 372 TYR A CG  1 
ATOM   2220 C  CD1 . TYR A 1 372 ? 114.629 113.969 80.176  1.00 142.32 ? 372 TYR A CD1 1 
ATOM   2221 C  CD2 . TYR A 1 372 ? 113.721 114.102 77.981  1.00 141.80 ? 372 TYR A CD2 1 
ATOM   2222 C  CE1 . TYR A 1 372 ? 113.709 112.999 80.506  1.00 141.05 ? 372 TYR A CE1 1 
ATOM   2223 C  CE2 . TYR A 1 372 ? 112.797 113.130 78.301  1.00 142.47 ? 372 TYR A CE2 1 
ATOM   2224 C  CZ  . TYR A 1 372 ? 112.796 112.582 79.565  1.00 144.23 ? 372 TYR A CZ  1 
ATOM   2225 O  OH  . TYR A 1 372 ? 111.876 111.613 79.890  1.00 146.32 ? 372 TYR A OH  1 
ATOM   2226 N  N   . GLN A 1 373 ? 118.133 112.943 78.276  1.00 160.99 ? 373 GLN A N   1 
ATOM   2227 C  CA  . GLN A 1 373 ? 118.251 111.642 77.645  1.00 162.65 ? 373 GLN A CA  1 
ATOM   2228 C  C   . GLN A 1 373 ? 117.022 110.795 77.970  1.00 163.66 ? 373 GLN A C   1 
ATOM   2229 O  O   . GLN A 1 373 ? 116.361 111.011 78.989  1.00 162.17 ? 373 GLN A O   1 
ATOM   2230 C  CB  . GLN A 1 373 ? 119.514 110.930 78.119  1.00 160.89 ? 373 GLN A CB  1 
ATOM   2231 C  CG  . GLN A 1 373 ? 120.672 111.863 78.418  1.00 162.31 ? 373 GLN A CG  1 
ATOM   2232 C  CD  . GLN A 1 373 ? 121.591 112.047 77.229  1.00 164.60 ? 373 GLN A CD  1 
ATOM   2233 O  OE1 . GLN A 1 373 ? 121.145 112.077 76.083  1.00 164.48 ? 373 GLN A OE1 1 
ATOM   2234 N  NE2 . GLN A 1 373 ? 122.885 112.171 77.497  1.00 162.42 ? 373 GLN A NE2 1 
ATOM   2235 N  N   . PRO A 1 374 ? 116.682 109.831 77.113  1.00 175.90 ? 374 PRO A N   1 
ATOM   2236 C  CA  . PRO A 1 374 ? 115.575 108.921 77.445  1.00 175.14 ? 374 PRO A CA  1 
ATOM   2237 C  C   . PRO A 1 374 ? 115.823 108.107 78.702  1.00 174.50 ? 374 PRO A C   1 
ATOM   2238 O  O   . PRO A 1 374 ? 114.859 107.637 79.318  1.00 171.35 ? 374 PRO A O   1 
ATOM   2239 C  CB  . PRO A 1 374 ? 115.472 108.023 76.205  1.00 173.88 ? 374 PRO A CB  1 
ATOM   2240 C  CG  . PRO A 1 374 ? 116.088 108.825 75.105  1.00 173.72 ? 374 PRO A CG  1 
ATOM   2241 C  CD  . PRO A 1 374 ? 117.186 109.616 75.746  1.00 173.33 ? 374 PRO A CD  1 
ATOM   2242 N  N   . GLU A 1 375 ? 117.081 107.927 79.103  1.00 180.68 ? 375 GLU A N   1 
ATOM   2243 C  CA  . GLU A 1 375 ? 117.408 107.193 80.318  1.00 180.64 ? 375 GLU A CA  1 
ATOM   2244 C  C   . GLU A 1 375 ? 117.256 108.033 81.579  1.00 181.89 ? 375 GLU A C   1 
ATOM   2245 O  O   . GLU A 1 375 ? 117.379 107.489 82.681  1.00 182.24 ? 375 GLU A O   1 
ATOM   2246 C  CB  . GLU A 1 375 ? 118.837 106.652 80.230  1.00 180.04 ? 375 GLU A CB  1 
ATOM   2247 C  CG  . GLU A 1 375 ? 119.054 105.333 80.953  1.00 181.28 ? 375 GLU A CG  1 
ATOM   2248 C  CD  . GLU A 1 375 ? 119.889 105.490 82.208  1.00 181.61 ? 375 GLU A CD  1 
ATOM   2249 O  OE1 . GLU A 1 375 ? 120.202 106.642 82.573  1.00 182.00 ? 375 GLU A OE1 1 
ATOM   2250 O  OE2 . GLU A 1 375 ? 120.235 104.462 82.828  1.00 178.98 ? 375 GLU A OE2 1 
ATOM   2251 N  N   . MET A 1 376 ? 117.001 109.338 81.446  1.00 178.62 ? 376 MET A N   1 
ATOM   2252 C  CA  . MET A 1 376 ? 116.830 110.187 82.621  1.00 177.55 ? 376 MET A CA  1 
ATOM   2253 C  C   . MET A 1 376 ? 115.624 109.757 83.447  1.00 178.19 ? 376 MET A C   1 
ATOM   2254 O  O   . MET A 1 376 ? 115.685 109.732 84.681  1.00 176.71 ? 376 MET A O   1 
ATOM   2255 C  CB  . MET A 1 376 ? 116.691 111.649 82.196  1.00 177.32 ? 376 MET A CB  1 
ATOM   2256 C  CG  . MET A 1 376 ? 117.889 112.210 81.450  1.00 177.47 ? 376 MET A CG  1 
ATOM   2257 S  SD  . MET A 1 376 ? 118.540 113.720 82.187  1.00 177.74 ? 376 MET A SD  1 
ATOM   2258 C  CE  . MET A 1 376 ? 119.523 113.056 83.521  1.00 176.14 ? 376 MET A CE  1 
ATOM   2259 N  N   . ALA A 1 377 ? 114.522 109.412 82.785  1.00 185.91 ? 377 ALA A N   1 
ATOM   2260 C  CA  . ALA A 1 377 ? 113.292 109.027 83.465  1.00 185.42 ? 377 ALA A CA  1 
ATOM   2261 C  C   . ALA A 1 377 ? 113.328 107.604 84.005  1.00 186.87 ? 377 ALA A C   1 
ATOM   2262 O  O   . ALA A 1 377 ? 112.283 107.086 84.412  1.00 186.54 ? 377 ALA A O   1 
ATOM   2263 C  CB  . ALA A 1 377 ? 112.097 109.191 82.523  1.00 183.49 ? 377 ALA A CB  1 
ATOM   2264 N  N   . GLN A 1 378 ? 114.493 106.963 84.017  1.00 194.35 ? 378 GLN A N   1 
ATOM   2265 C  CA  . GLN A 1 378 ? 114.632 105.607 84.525  1.00 193.06 ? 378 GLN A CA  1 
ATOM   2266 C  C   . GLN A 1 378 ? 115.531 105.501 85.745  1.00 192.48 ? 378 GLN A C   1 
ATOM   2267 O  O   . GLN A 1 378 ? 115.368 104.564 86.530  1.00 191.26 ? 378 GLN A O   1 
ATOM   2268 C  CB  . GLN A 1 378 ? 115.176 104.679 83.428  1.00 191.39 ? 378 GLN A CB  1 
ATOM   2269 C  CG  . GLN A 1 378 ? 114.805 103.218 83.611  1.00 192.18 ? 378 GLN A CG  1 
ATOM   2270 C  CD  . GLN A 1 378 ? 113.314 102.979 83.484  1.00 193.72 ? 378 GLN A CD  1 
ATOM   2271 O  OE1 . GLN A 1 378 ? 112.638 103.615 82.675  1.00 192.96 ? 378 GLN A OE1 1 
ATOM   2272 N  NE2 . GLN A 1 378 ? 112.792 102.059 84.286  1.00 193.10 ? 378 GLN A NE2 1 
ATOM   2273 N  N   . CYS A 1 379 ? 116.469 106.427 85.929  1.00 195.42 ? 379 CYS A N   1 
ATOM   2274 C  CA  . CYS A 1 379 ? 117.374 106.360 87.066  1.00 195.22 ? 379 CYS A CA  1 
ATOM   2275 C  C   . CYS A 1 379 ? 116.625 106.616 88.367  1.00 194.85 ? 379 CYS A C   1 
ATOM   2276 O  O   . CYS A 1 379 ? 115.758 107.490 88.443  1.00 195.57 ? 379 CYS A O   1 
ATOM   2277 C  CB  . CYS A 1 379 ? 118.507 107.372 86.907  1.00 195.29 ? 379 CYS A CB  1 
ATOM   2278 S  SG  . CYS A 1 379 ? 119.672 107.397 88.289  1.00 199.48 ? 379 CYS A SG  1 
ATOM   2279 N  N   . LEU A 1 380 ? 116.964 105.836 89.395  1.00 189.07 ? 380 LEU A N   1 
ATOM   2280 C  CA  . LEU A 1 380 ? 116.334 106.017 90.698  1.00 189.77 ? 380 LEU A CA  1 
ATOM   2281 C  C   . LEU A 1 380 ? 116.731 107.349 91.323  1.00 191.70 ? 380 LEU A C   1 
ATOM   2282 O  O   . LEU A 1 380 ? 115.907 108.008 91.967  1.00 190.35 ? 380 LEU A O   1 
ATOM   2283 C  CB  . LEU A 1 380 ? 116.702 104.856 91.622  1.00 190.32 ? 380 LEU A CB  1 
ATOM   2284 C  CG  . LEU A 1 380 ? 116.128 104.884 93.040  1.00 191.35 ? 380 LEU A CG  1 
ATOM   2285 C  CD1 . LEU A 1 380 ? 115.461 103.559 93.373  1.00 188.53 ? 380 LEU A CD1 1 
ATOM   2286 C  CD2 . LEU A 1 380 ? 117.210 105.211 94.058  1.00 190.32 ? 380 LEU A CD2 1 
ATOM   2287 N  N   . ARG A 1 381 ? 117.985 107.761 91.144  1.00 193.89 ? 381 ARG A N   1 
ATOM   2288 C  CA  . ARG A 1 381 ? 118.473 109.000 91.735  1.00 191.49 ? 381 ARG A CA  1 
ATOM   2289 C  C   . ARG A 1 381 ? 117.973 110.244 91.014  1.00 190.37 ? 381 ARG A C   1 
ATOM   2290 O  O   . ARG A 1 381 ? 118.142 111.350 91.537  1.00 188.81 ? 381 ARG A O   1 
ATOM   2291 C  CB  . ARG A 1 381 ? 120.002 109.001 91.760  1.00 190.72 ? 381 ARG A CB  1 
ATOM   2292 C  CG  . ARG A 1 381 ? 120.615 107.646 92.063  1.00 190.42 ? 381 ARG A CG  1 
ATOM   2293 C  CD  . ARG A 1 381 ? 121.965 107.491 91.388  1.00 191.76 ? 381 ARG A CD  1 
ATOM   2294 N  NE  . ARG A 1 381 ? 122.833 108.633 91.649  1.00 193.27 ? 381 ARG A NE  1 
ATOM   2295 C  CZ  . ARG A 1 381 ? 123.539 108.798 92.759  1.00 193.02 ? 381 ARG A CZ  1 
ATOM   2296 N  NH1 . ARG A 1 381 ? 123.508 107.908 93.737  1.00 191.64 ? 381 ARG A NH1 1 
ATOM   2297 N  NH2 . ARG A 1 381 ? 124.296 109.884 92.891  1.00 192.12 ? 381 ARG A NH2 1 
ATOM   2298 N  N   . CYS A 1 382 ? 117.371 110.098 89.835  1.00 181.71 ? 382 CYS A N   1 
ATOM   2299 C  CA  . CYS A 1 382 ? 116.804 111.221 89.103  1.00 179.79 ? 382 CYS A CA  1 
ATOM   2300 C  C   . CYS A 1 382 ? 115.325 111.428 89.409  1.00 180.87 ? 382 CYS A C   1 
ATOM   2301 O  O   . CYS A 1 382 ? 114.612 112.030 88.598  1.00 180.10 ? 382 CYS A O   1 
ATOM   2302 C  CB  . CYS A 1 382 ? 117.005 111.030 87.598  1.00 179.30 ? 382 CYS A CB  1 
ATOM   2303 S  SG  . CYS A 1 382 ? 118.730 110.996 87.058  1.00 184.60 ? 382 CYS A SG  1 
ATOM   2304 N  N   . GLN A 1 383 ? 114.850 110.943 90.552  1.00 181.99 ? 383 GLN A N   1 
ATOM   2305 C  CA  . GLN A 1 383 ? 113.450 111.043 90.935  1.00 180.84 ? 383 GLN A CA  1 
ATOM   2306 C  C   . GLN A 1 383 ? 113.300 111.956 92.144  1.00 180.20 ? 383 GLN A C   1 
ATOM   2307 O  O   . GLN A 1 383 ? 114.081 111.877 93.097  1.00 180.06 ? 383 GLN A O   1 
ATOM   2308 C  CB  . GLN A 1 383 ? 112.866 109.664 91.250  1.00 179.61 ? 383 GLN A CB  1 
ATOM   2309 C  CG  . GLN A 1 383 ? 113.207 108.601 90.223  1.00 179.95 ? 383 GLN A CG  1 
ATOM   2310 C  CD  . GLN A 1 383 ? 112.535 108.848 88.888  1.00 180.77 ? 383 GLN A CD  1 
ATOM   2311 O  OE1 . GLN A 1 383 ? 111.431 109.388 88.828  1.00 180.55 ? 383 GLN A OE1 1 
ATOM   2312 N  NE2 . GLN A 1 383 ? 113.200 108.455 87.809  1.00 180.44 ? 383 GLN A NE2 1 
ATOM   2313 N  N   . GLU A 1 384 ? 112.289 112.820 92.098  1.00 164.49 ? 384 GLU A N   1 
ATOM   2314 C  CA  . GLU A 1 384 ? 112.049 113.759 93.178  1.00 167.17 ? 384 GLU A CA  1 
ATOM   2315 C  C   . GLU A 1 384 ? 111.513 113.036 94.413  1.00 164.81 ? 384 GLU A C   1 
ATOM   2316 O  O   . GLU A 1 384 ? 110.963 111.937 94.312  1.00 163.75 ? 384 GLU A O   1 
ATOM   2317 C  CB  . GLU A 1 384 ? 111.069 114.840 92.729  1.00 165.18 ? 384 GLU A CB  1 
ATOM   2318 C  CG  . GLU A 1 384 ? 111.512 115.596 91.486  1.00 163.15 ? 384 GLU A CG  1 
ATOM   2319 C  CD  . GLU A 1 384 ? 112.424 116.768 91.803  1.00 164.41 ? 384 GLU A CD  1 
ATOM   2320 O  OE1 . GLU A 1 384 ? 113.452 116.565 92.483  1.00 161.90 ? 384 GLU A OE1 1 
ATOM   2321 O  OE2 . GLU A 1 384 ? 112.113 117.895 91.367  1.00 164.74 ? 384 GLU A OE2 1 
ATOM   2322 N  N   . PRO A 1 385 ? 111.686 113.628 95.593  1.00 155.41 ? 385 PRO A N   1 
ATOM   2323 C  CA  . PRO A 1 385 ? 111.156 113.007 96.803  1.00 155.39 ? 385 PRO A CA  1 
ATOM   2324 C  C   . PRO A 1 385 ? 109.649 112.870 96.721  1.00 155.52 ? 385 PRO A C   1 
ATOM   2325 O  O   . PRO A 1 385 ? 108.966 113.691 96.082  1.00 152.10 ? 385 PRO A O   1 
ATOM   2326 C  CB  . PRO A 1 385 ? 111.571 113.981 97.916  1.00 154.53 ? 385 PRO A CB  1 
ATOM   2327 C  CG  . PRO A 1 385 ? 112.288 115.107 97.267  1.00 151.97 ? 385 PRO A CG  1 
ATOM   2328 C  CD  . PRO A 1 385 ? 112.628 114.719 95.882  1.00 155.28 ? 385 PRO A CD  1 
ATOM   2329 N  N   . PRO A 1 386 ? 109.086 111.842 97.351  1.00 169.93 ? 386 PRO A N   1 
ATOM   2330 C  CA  . PRO A 1 386 ? 107.637 111.636 97.278  1.00 167.84 ? 386 PRO A CA  1 
ATOM   2331 C  C   . PRO A 1 386 ? 106.880 112.687 98.074  1.00 170.23 ? 386 PRO A C   1 
ATOM   2332 O  O   . PRO A 1 386 ? 107.413 113.333 98.979  1.00 170.14 ? 386 PRO A O   1 
ATOM   2333 C  CB  . PRO A 1 386 ? 107.433 110.237 97.877  1.00 167.59 ? 386 PRO A CB  1 
ATOM   2334 C  CG  . PRO A 1 386 ? 108.792 109.751 98.307  1.00 168.06 ? 386 PRO A CG  1 
ATOM   2335 C  CD  . PRO A 1 386 ? 109.737 110.904 98.276  1.00 169.13 ? 386 PRO A CD  1 
ATOM   2336 N  N   . GLN A 1 387 ? 105.609 112.851 97.711  1.00 168.68 ? 387 GLN A N   1 
ATOM   2337 C  CA  . GLN A 1 387 ? 104.756 113.829 98.372  1.00 169.00 ? 387 GLN A CA  1 
ATOM   2338 C  C   . GLN A 1 387 ? 104.605 113.501 99.852  1.00 169.63 ? 387 GLN A C   1 
ATOM   2339 O  O   . GLN A 1 387 ? 104.525 112.333 100.243 1.00 168.05 ? 387 GLN A O   1 
ATOM   2340 C  CB  . GLN A 1 387 ? 103.383 113.868 97.701  1.00 167.72 ? 387 GLN A CB  1 
ATOM   2341 C  CG  . GLN A 1 387 ? 102.602 115.147 97.949  1.00 168.13 ? 387 GLN A CG  1 
ATOM   2342 C  CD  . GLN A 1 387 ? 102.618 116.080 96.756  1.00 167.71 ? 387 GLN A CD  1 
ATOM   2343 O  OE1 . GLN A 1 387 ? 103.649 116.263 96.110  1.00 167.11 ? 387 GLN A OE1 1 
ATOM   2344 N  NE2 . GLN A 1 387 ? 101.470 116.676 96.456  1.00 166.84 ? 387 GLN A NE2 1 
ATOM   2345 N  N   . ALA A 1 388 ? 104.571 114.542 100.675 1.00 176.51 ? 388 ALA A N   1 
ATOM   2346 C  CA  . ALA A 1 388 ? 104.421 114.375 102.115 1.00 176.91 ? 388 ALA A CA  1 
ATOM   2347 C  C   . ALA A 1 388 ? 102.991 113.984 102.469 1.00 176.94 ? 388 ALA A C   1 
ATOM   2348 O  O   . ALA A 1 388 ? 102.078 114.136 101.658 1.00 176.54 ? 388 ALA A O   1 
ATOM   2349 C  CB  . ALA A 1 388 ? 104.818 115.649 102.841 1.00 174.61 ? 388 ALA A CB  1 
ATOM   2350 N  N   . HIS B 1 54  ? 124.367 112.029 81.626  1.00 181.65 ? 54  HIS B N   1 
ATOM   2351 C  CA  . HIS B 1 54  ? 123.527 111.832 82.801  1.00 184.15 ? 54  HIS B CA  1 
ATOM   2352 C  C   . HIS B 1 54  ? 124.318 112.088 84.080  1.00 184.21 ? 54  HIS B C   1 
ATOM   2353 O  O   . HIS B 1 54  ? 125.212 111.318 84.431  1.00 180.85 ? 54  HIS B O   1 
ATOM   2354 C  CB  . HIS B 1 54  ? 122.941 110.417 82.809  1.00 181.59 ? 54  HIS B CB  1 
ATOM   2355 C  CG  . HIS B 1 54  ? 121.776 110.244 83.735  1.00 181.42 ? 54  HIS B CG  1 
ATOM   2356 N  ND1 . HIS B 1 54  ? 120.697 109.443 83.434  1.00 184.34 ? 54  HIS B ND1 1 
ATOM   2357 C  CD2 . HIS B 1 54  ? 121.525 110.766 84.959  1.00 180.89 ? 54  HIS B CD2 1 
ATOM   2358 C  CE1 . HIS B 1 54  ? 119.830 109.480 84.431  1.00 186.25 ? 54  HIS B CE1 1 
ATOM   2359 N  NE2 . HIS B 1 54  ? 120.309 110.277 85.369  1.00 185.06 ? 54  HIS B NE2 1 
ATOM   2360 N  N   . CYS B 1 55  ? 123.984 113.177 84.769  1.00 170.71 ? 55  CYS B N   1 
ATOM   2361 C  CA  . CYS B 1 55  ? 124.609 113.479 86.048  1.00 167.48 ? 55  CYS B CA  1 
ATOM   2362 C  C   . CYS B 1 55  ? 124.244 112.413 87.073  1.00 171.58 ? 55  CYS B C   1 
ATOM   2363 O  O   . CYS B 1 55  ? 123.220 111.743 86.955  1.00 172.64 ? 55  CYS B O   1 
ATOM   2364 C  CB  . CYS B 1 55  ? 124.173 114.857 86.544  1.00 165.74 ? 55  CYS B CB  1 
ATOM   2365 S  SG  . CYS B 1 55  ? 122.386 115.070 86.721  1.00 159.30 ? 55  CYS B SG  1 
ATOM   2366 N  N   . HIS B 1 56  ? 125.134 112.218 88.050  1.00 188.95 ? 56  HIS B N   1 
ATOM   2367 C  CA  . HIS B 1 56  ? 124.946 111.297 89.173  1.00 189.43 ? 56  HIS B CA  1 
ATOM   2368 C  C   . HIS B 1 56  ? 124.747 109.850 88.729  1.00 189.63 ? 56  HIS B C   1 
ATOM   2369 O  O   . HIS B 1 56  ? 124.504 108.973 89.565  1.00 189.11 ? 56  HIS B O   1 
ATOM   2370 C  CB  . HIS B 1 56  ? 123.782 111.750 90.080  1.00 187.62 ? 56  HIS B CB  1 
ATOM   2371 C  CG  . HIS B 1 56  ? 122.413 111.488 89.525  1.00 187.66 ? 56  HIS B CG  1 
ATOM   2372 N  ND1 . HIS B 1 56  ? 121.502 112.499 89.305  1.00 186.63 ? 56  HIS B ND1 1 
ATOM   2373 C  CD2 . HIS B 1 56  ? 121.798 110.342 89.144  1.00 188.64 ? 56  HIS B CD2 1 
ATOM   2374 C  CE1 . HIS B 1 56  ? 120.389 111.988 88.810  1.00 187.98 ? 56  HIS B CE1 1 
ATOM   2375 N  NE2 . HIS B 1 56  ? 120.544 110.682 88.696  1.00 190.59 ? 56  HIS B NE2 1 
ATOM   2376 N  N   . ARG B 1 57  ? 124.851 109.582 87.428  1.00 197.00 ? 57  ARG B N   1 
ATOM   2377 C  CA  . ARG B 1 57  ? 124.628 108.237 86.916  1.00 198.14 ? 57  ARG B CA  1 
ATOM   2378 C  C   . ARG B 1 57  ? 125.880 107.373 86.935  1.00 200.49 ? 57  ARG B C   1 
ATOM   2379 O  O   . ARG B 1 57  ? 125.770 106.149 86.798  1.00 200.46 ? 57  ARG B O   1 
ATOM   2380 C  CB  . ARG B 1 57  ? 124.079 108.299 85.488  1.00 198.91 ? 57  ARG B CB  1 
ATOM   2381 C  CG  . ARG B 1 57  ? 123.217 107.107 85.103  1.00 197.68 ? 57  ARG B CG  1 
ATOM   2382 C  CD  . ARG B 1 57  ? 123.261 106.857 83.605  1.00 197.06 ? 57  ARG B CD  1 
ATOM   2383 N  NE  . ARG B 1 57  ? 124.550 107.218 83.028  1.00 198.23 ? 57  ARG B NE  1 
ATOM   2384 C  CZ  . ARG B 1 57  ? 125.523 106.355 82.770  1.00 197.47 ? 57  ARG B CZ  1 
ATOM   2385 N  NH1 . ARG B 1 57  ? 125.388 105.064 83.024  1.00 196.57 ? 57  ARG B NH1 1 
ATOM   2386 N  NH2 . ARG B 1 57  ? 126.661 106.799 82.243  1.00 195.40 ? 57  ARG B NH2 1 
ATOM   2387 N  N   . ASP B 1 58  ? 127.059 107.972 87.093  1.00 211.21 ? 58  ASP B N   1 
ATOM   2388 C  CA  . ASP B 1 58  ? 128.284 107.178 87.161  1.00 211.15 ? 58  ASP B CA  1 
ATOM   2389 C  C   . ASP B 1 58  ? 128.310 106.238 88.361  1.00 211.02 ? 58  ASP B C   1 
ATOM   2390 O  O   . ASP B 1 58  ? 128.607 105.046 88.172  1.00 209.97 ? 58  ASP B O   1 
ATOM   2391 C  CB  . ASP B 1 58  ? 129.502 108.109 87.138  1.00 209.61 ? 58  ASP B CB  1 
ATOM   2392 C  CG  . ASP B 1 58  ? 129.596 108.911 85.855  1.00 208.64 ? 58  ASP B CG  1 
ATOM   2393 O  OD1 . ASP B 1 58  ? 128.628 108.884 85.066  1.00 207.15 ? 58  ASP B OD1 1 
ATOM   2394 O  OD2 . ASP B 1 58  ? 130.635 109.568 85.637  1.00 207.31 ? 58  ASP B OD2 1 
ATOM   2395 N  N   . PRO B 1 59  ? 128.017 106.677 89.602  1.00 209.44 ? 59  PRO B N   1 
ATOM   2396 C  CA  . PRO B 1 59  ? 127.966 105.714 90.708  1.00 208.44 ? 59  PRO B CA  1 
ATOM   2397 C  C   . PRO B 1 59  ? 126.582 105.109 90.878  1.00 208.00 ? 59  PRO B C   1 
ATOM   2398 O  O   . PRO B 1 59  ? 125.660 105.428 90.120  1.00 207.16 ? 59  PRO B O   1 
ATOM   2399 C  CB  . PRO B 1 59  ? 128.365 106.560 91.919  1.00 205.85 ? 59  PRO B CB  1 
ATOM   2400 C  CG  . PRO B 1 59  ? 127.841 107.918 91.595  1.00 204.71 ? 59  PRO B CG  1 
ATOM   2401 C  CD  . PRO B 1 59  ? 127.808 108.056 90.086  1.00 206.42 ? 59  PRO B CD  1 
ATOM   2402 N  N   . LEU B 1 60  ? 126.425 104.234 91.866  1.00 212.05 ? 60  LEU B N   1 
ATOM   2403 C  CA  . LEU B 1 60  ? 125.147 103.613 92.163  1.00 212.81 ? 60  LEU B CA  1 
ATOM   2404 C  C   . LEU B 1 60  ? 124.884 103.656 93.660  1.00 213.08 ? 60  LEU B C   1 
ATOM   2405 O  O   . LEU B 1 60  ? 125.818 103.550 94.462  1.00 211.32 ? 60  LEU B O   1 
ATOM   2406 C  CB  . LEU B 1 60  ? 125.111 102.157 91.677  1.00 212.56 ? 60  LEU B CB  1 
ATOM   2407 C  CG  . LEU B 1 60  ? 125.179 101.954 90.162  1.00 211.18 ? 60  LEU B CG  1 
ATOM   2408 C  CD1 . LEU B 1 60  ? 125.346 100.482 89.823  1.00 209.91 ? 60  LEU B CD1 1 
ATOM   2409 C  CD2 . LEU B 1 60  ? 123.942 102.527 89.488  1.00 210.71 ? 60  LEU B CD2 1 
ATOM   2410 N  N   . PRO B 1 61  ? 123.627 103.812 94.065  1.00 220.89 ? 61  PRO B N   1 
ATOM   2411 C  CA  . PRO B 1 61  ? 123.306 103.843 95.493  1.00 221.41 ? 61  PRO B CA  1 
ATOM   2412 C  C   . PRO B 1 61  ? 123.042 102.446 96.025  1.00 221.73 ? 61  PRO B C   1 
ATOM   2413 O  O   . PRO B 1 61  ? 122.211 101.707 95.475  1.00 220.44 ? 61  PRO B O   1 
ATOM   2414 C  CB  . PRO B 1 61  ? 122.042 104.712 95.549  1.00 220.07 ? 61  PRO B CB  1 
ATOM   2415 C  CG  . PRO B 1 61  ? 121.396 104.534 94.204  1.00 218.42 ? 61  PRO B CG  1 
ATOM   2416 C  CD  . PRO B 1 61  ? 122.445 104.061 93.222  1.00 218.56 ? 61  PRO B CD  1 
ATOM   2417 N  N   . PRO B 1 62  ? 123.726 102.046 97.092  1.00 225.61 ? 62  PRO B N   1 
ATOM   2418 C  CA  . PRO B 1 62  ? 123.489 100.724 97.674  1.00 225.00 ? 62  PRO B CA  1 
ATOM   2419 C  C   . PRO B 1 62  ? 122.334 100.761 98.657  1.00 225.01 ? 62  PRO B C   1 
ATOM   2420 O  O   . PRO B 1 62  ? 122.390 101.471 99.672  1.00 222.87 ? 62  PRO B O   1 
ATOM   2421 C  CB  . PRO B 1 62  ? 124.816 100.406 98.379  1.00 222.94 ? 62  PRO B CB  1 
ATOM   2422 C  CG  . PRO B 1 62  ? 125.439 101.746 98.667  1.00 221.94 ? 62  PRO B CG  1 
ATOM   2423 C  CD  . PRO B 1 62  ? 124.770 102.795 97.812  1.00 223.14 ? 62  PRO B CD  1 
ATOM   2424 N  N   . PRO B 1 63  ? 121.268 100.013 98.393  1.00 224.80 ? 63  PRO B N   1 
ATOM   2425 C  CA  . PRO B 1 63  ? 120.125 99.983  99.305  1.00 223.55 ? 63  PRO B CA  1 
ATOM   2426 C  C   . PRO B 1 63  ? 120.308 98.939  100.401 1.00 223.18 ? 63  PRO B C   1 
ATOM   2427 O  O   . PRO B 1 63  ? 121.235 98.127  100.381 1.00 221.84 ? 63  PRO B O   1 
ATOM   2428 C  CB  . PRO B 1 63  ? 118.960 99.610  98.380  1.00 222.42 ? 63  PRO B CB  1 
ATOM   2429 C  CG  . PRO B 1 63  ? 119.593 98.765  97.319  1.00 222.48 ? 63  PRO B CG  1 
ATOM   2430 C  CD  . PRO B 1 63  ? 121.045 99.179  97.199  1.00 223.12 ? 63  PRO B CD  1 
ATOM   2431 N  N   . GLY B 1 64  ? 119.392 98.976  101.365 1.00 208.98 ? 64  GLY B N   1 
ATOM   2432 C  CA  . GLY B 1 64  ? 119.425 98.041  102.468 1.00 208.03 ? 64  GLY B CA  1 
ATOM   2433 C  C   . GLY B 1 64  ? 120.481 98.392  103.499 1.00 209.31 ? 64  GLY B C   1 
ATOM   2434 O  O   . GLY B 1 64  ? 121.052 99.486  103.518 1.00 208.70 ? 64  GLY B O   1 
ATOM   2435 N  N   . LEU B 1 65  ? 120.739 97.428  104.378 1.00 197.77 ? 65  LEU B N   1 
ATOM   2436 C  CA  . LEU B 1 65  ? 121.717 97.572  105.449 1.00 197.67 ? 65  LEU B CA  1 
ATOM   2437 C  C   . LEU B 1 65  ? 122.888 96.638  105.177 1.00 196.48 ? 65  LEU B C   1 
ATOM   2438 O  O   . LEU B 1 65  ? 122.700 95.424  105.042 1.00 194.66 ? 65  LEU B O   1 
ATOM   2439 C  CB  . LEU B 1 65  ? 121.089 97.265  106.808 1.00 196.63 ? 65  LEU B CB  1 
ATOM   2440 C  CG  . LEU B 1 65  ? 119.774 97.974  107.140 1.00 195.41 ? 65  LEU B CG  1 
ATOM   2441 C  CD1 . LEU B 1 65  ? 119.391 97.728  108.590 1.00 194.08 ? 65  LEU B CD1 1 
ATOM   2442 C  CD2 . LEU B 1 65  ? 119.871 99.465  106.856 1.00 194.83 ? 65  LEU B CD2 1 
ATOM   2443 N  N   . THR B 1 66  ? 124.089 97.203  105.100 1.00 193.03 ? 66  THR B N   1 
ATOM   2444 C  CA  . THR B 1 66  ? 125.270 96.392  104.856 1.00 192.86 ? 66  THR B CA  1 
ATOM   2445 C  C   . THR B 1 66  ? 125.564 95.518  106.073 1.00 193.33 ? 66  THR B C   1 
ATOM   2446 O  O   . THR B 1 66  ? 125.314 95.932  107.209 1.00 193.84 ? 66  THR B O   1 
ATOM   2447 C  CB  . THR B 1 66  ? 126.478 97.274  104.546 1.00 191.20 ? 66  THR B CB  1 
ATOM   2448 O  OG1 . THR B 1 66  ? 126.977 97.846  105.761 1.00 192.18 ? 66  THR B OG1 1 
ATOM   2449 C  CG2 . THR B 1 66  ? 126.087 98.392  103.594 1.00 189.64 ? 66  THR B CG2 1 
ATOM   2450 N  N   . PRO B 1 67  ? 126.083 94.304  105.870 1.00 190.42 ? 67  PRO B N   1 
ATOM   2451 C  CA  . PRO B 1 67  ? 126.393 93.441  107.022 1.00 189.79 ? 67  PRO B CA  1 
ATOM   2452 C  C   . PRO B 1 67  ? 127.384 94.056  107.991 1.00 189.94 ? 67  PRO B C   1 
ATOM   2453 O  O   . PRO B 1 67  ? 127.271 93.832  109.203 1.00 189.05 ? 67  PRO B O   1 
ATOM   2454 C  CB  . PRO B 1 67  ? 126.958 92.173  106.366 1.00 187.73 ? 67  PRO B CB  1 
ATOM   2455 C  CG  . PRO B 1 67  ? 126.419 92.188  104.976 1.00 188.50 ? 67  PRO B CG  1 
ATOM   2456 C  CD  . PRO B 1 67  ? 126.340 93.631  104.586 1.00 189.18 ? 67  PRO B CD  1 
ATOM   2457 N  N   . GLU B 1 68  ? 128.356 94.827  107.498 1.00 188.74 ? 68  GLU B N   1 
ATOM   2458 C  CA  . GLU B 1 68  ? 129.318 95.454  108.397 1.00 188.45 ? 68  GLU B CA  1 
ATOM   2459 C  C   . GLU B 1 68  ? 128.669 96.539  109.245 1.00 189.35 ? 68  GLU B C   1 
ATOM   2460 O  O   . GLU B 1 68  ? 129.099 96.774  110.380 1.00 190.67 ? 68  GLU B O   1 
ATOM   2461 C  CB  . GLU B 1 68  ? 130.490 96.029  107.601 1.00 188.39 ? 68  GLU B CB  1 
ATOM   2462 C  CG  . GLU B 1 68  ? 130.100 97.099  106.598 1.00 188.97 ? 68  GLU B CG  1 
ATOM   2463 C  CD  . GLU B 1 68  ? 130.244 98.499  107.161 1.00 190.35 ? 68  GLU B CD  1 
ATOM   2464 O  OE1 . GLU B 1 68  ? 130.783 98.637  108.279 1.00 189.84 ? 68  GLU B OE1 1 
ATOM   2465 O  OE2 . GLU B 1 68  ? 129.816 99.460  106.489 1.00 191.14 ? 68  GLU B OE2 1 
ATOM   2466 N  N   . ARG B 1 69  ? 127.645 97.213  108.718 1.00 183.64 ? 69  ARG B N   1 
ATOM   2467 C  CA  . ARG B 1 69  ? 126.970 98.241  109.501 1.00 182.75 ? 69  ARG B CA  1 
ATOM   2468 C  C   . ARG B 1 69  ? 126.194 97.638  110.663 1.00 183.00 ? 69  ARG B C   1 
ATOM   2469 O  O   . ARG B 1 69  ? 126.090 98.263  111.724 1.00 184.85 ? 69  ARG B O   1 
ATOM   2470 C  CB  . ARG B 1 69  ? 126.048 99.069  108.610 1.00 182.89 ? 69  ARG B CB  1 
ATOM   2471 C  CG  . ARG B 1 69  ? 126.667 100.379 108.150 1.00 182.72 ? 69  ARG B CG  1 
ATOM   2472 C  CD  . ARG B 1 69  ? 125.605 101.380 107.730 1.00 184.30 ? 69  ARG B CD  1 
ATOM   2473 N  NE  . ARG B 1 69  ? 125.089 101.101 106.396 1.00 187.24 ? 69  ARG B NE  1 
ATOM   2474 C  CZ  . ARG B 1 69  ? 123.930 100.506 106.152 1.00 187.44 ? 69  ARG B CZ  1 
ATOM   2475 N  NH1 . ARG B 1 69  ? 123.136 100.112 107.133 1.00 184.31 ? 69  ARG B NH1 1 
ATOM   2476 N  NH2 . ARG B 1 69  ? 123.558 100.302 104.891 1.00 185.78 ? 69  ARG B NH2 1 
ATOM   2477 N  N   . LEU B 1 70  ? 125.650 96.432  110.491 1.00 169.90 ? 70  LEU B N   1 
ATOM   2478 C  CA  . LEU B 1 70  ? 125.035 95.742  111.621 1.00 171.66 ? 70  LEU B CA  1 
ATOM   2479 C  C   . LEU B 1 70  ? 126.062 95.461  112.708 1.00 171.58 ? 70  LEU B C   1 
ATOM   2480 O  O   . LEU B 1 70  ? 125.780 95.625  113.902 1.00 172.60 ? 70  LEU B O   1 
ATOM   2481 C  CB  . LEU B 1 70  ? 124.377 94.442  111.157 1.00 171.89 ? 70  LEU B CB  1 
ATOM   2482 C  CG  . LEU B 1 70  ? 122.964 94.504  110.568 1.00 173.26 ? 70  LEU B CG  1 
ATOM   2483 C  CD1 . LEU B 1 70  ? 121.982 95.046  111.596 1.00 170.93 ? 70  LEU B CD1 1 
ATOM   2484 C  CD2 . LEU B 1 70  ? 122.910 95.319  109.287 1.00 173.74 ? 70  LEU B CD2 1 
ATOM   2485 N  N   . HIS B 1 71  ? 127.266 95.042  112.313 1.00 163.41 ? 71  HIS B N   1 
ATOM   2486 C  CA  . HIS B 1 71  ? 128.326 94.823  113.288 1.00 163.49 ? 71  HIS B CA  1 
ATOM   2487 C  C   . HIS B 1 71  ? 128.707 96.121  113.986 1.00 163.48 ? 71  HIS B C   1 
ATOM   2488 O  O   . HIS B 1 71  ? 128.931 96.136  115.201 1.00 167.42 ? 71  HIS B O   1 
ATOM   2489 C  CB  . HIS B 1 71  ? 129.544 94.201  112.612 1.00 161.39 ? 71  HIS B CB  1 
ATOM   2490 C  CG  . HIS B 1 71  ? 130.466 93.505  113.561 1.00 162.88 ? 71  HIS B CG  1 
ATOM   2491 N  ND1 . HIS B 1 71  ? 131.824 93.738  113.586 1.00 162.15 ? 71  HIS B ND1 1 
ATOM   2492 C  CD2 . HIS B 1 71  ? 130.224 92.585  114.524 1.00 163.38 ? 71  HIS B CD2 1 
ATOM   2493 C  CE1 . HIS B 1 71  ? 132.379 92.989  114.522 1.00 163.21 ? 71  HIS B CE1 1 
ATOM   2494 N  NE2 . HIS B 1 71  ? 131.430 92.280  115.106 1.00 164.55 ? 71  HIS B NE2 1 
ATOM   2495 N  N   . ALA B 1 72  ? 128.790 97.220  113.234 1.00 153.50 ? 72  ALA B N   1 
ATOM   2496 C  CA  . ALA B 1 72  ? 129.110 98.506  113.845 1.00 152.08 ? 72  ALA B CA  1 
ATOM   2497 C  C   . ALA B 1 72  ? 128.037 98.922  114.842 1.00 154.64 ? 72  ALA B C   1 
ATOM   2498 O  O   . ALA B 1 72  ? 128.347 99.437  115.924 1.00 159.60 ? 72  ALA B O   1 
ATOM   2499 C  CB  . ALA B 1 72  ? 129.285 99.573  112.767 1.00 151.08 ? 72  ALA B CB  1 
ATOM   2500 N  N   . ARG B 1 73  ? 126.768 98.705  114.496 1.00 148.83 ? 73  ARG B N   1 
ATOM   2501 C  CA  . ARG B 1 73  ? 125.685 99.012  115.423 1.00 148.59 ? 73  ARG B CA  1 
ATOM   2502 C  C   . ARG B 1 73  ? 125.781 98.159  116.680 1.00 150.17 ? 73  ARG B C   1 
ATOM   2503 O  O   . ARG B 1 73  ? 125.553 98.651  117.791 1.00 152.05 ? 73  ARG B O   1 
ATOM   2504 C  CB  . ARG B 1 73  ? 124.335 98.804  114.740 1.00 151.27 ? 73  ARG B CB  1 
ATOM   2505 C  CG  . ARG B 1 73  ? 123.909 99.953  113.851 1.00 152.94 ? 73  ARG B CG  1 
ATOM   2506 C  CD  . ARG B 1 73  ? 122.432 100.261 114.018 1.00 153.24 ? 73  ARG B CD  1 
ATOM   2507 N  NE  . ARG B 1 73  ? 121.591 99.331  113.273 1.00 155.11 ? 73  ARG B NE  1 
ATOM   2508 C  CZ  . ARG B 1 73  ? 120.948 98.306  113.815 1.00 154.55 ? 73  ARG B CZ  1 
ATOM   2509 N  NH1 . ARG B 1 73  ? 121.030 98.046  115.109 1.00 152.19 ? 73  ARG B NH1 1 
ATOM   2510 N  NH2 . ARG B 1 73  ? 120.205 97.524  113.039 1.00 153.19 ? 73  ARG B NH2 1 
ATOM   2511 N  N   . ARG B 1 74  ? 126.107 96.875  116.526 1.00 151.30 ? 74  ARG B N   1 
ATOM   2512 C  CA  . ARG B 1 74  ? 126.246 96.009  117.693 1.00 149.85 ? 74  ARG B CA  1 
ATOM   2513 C  C   . ARG B 1 74  ? 127.389 96.469  118.591 1.00 150.24 ? 74  ARG B C   1 
ATOM   2514 O  O   . ARG B 1 74  ? 127.253 96.492  119.821 1.00 153.74 ? 74  ARG B O   1 
ATOM   2515 C  CB  . ARG B 1 74  ? 126.456 94.563  117.250 1.00 149.89 ? 74  ARG B CB  1 
ATOM   2516 C  CG  . ARG B 1 74  ? 125.166 93.780  117.094 1.00 152.01 ? 74  ARG B CG  1 
ATOM   2517 C  CD  . ARG B 1 74  ? 125.426 92.382  116.564 1.00 153.10 ? 74  ARG B CD  1 
ATOM   2518 N  NE  . ARG B 1 74  ? 124.485 92.020  115.511 1.00 155.89 ? 74  ARG B NE  1 
ATOM   2519 C  CZ  . ARG B 1 74  ? 124.767 92.037  114.216 1.00 156.83 ? 74  ARG B CZ  1 
ATOM   2520 N  NH1 . ARG B 1 74  ? 125.962 92.389  113.773 1.00 155.41 ? 74  ARG B NH1 1 
ATOM   2521 N  NH2 . ARG B 1 74  ? 123.825 91.692  113.343 1.00 154.55 ? 74  ARG B NH2 1 
ATOM   2522 N  N   . GLN B 1 75  ? 128.524 96.838  117.993 1.00 141.94 ? 75  GLN B N   1 
ATOM   2523 C  CA  . GLN B 1 75  ? 129.641 97.340  118.787 1.00 142.12 ? 75  GLN B CA  1 
ATOM   2524 C  C   . GLN B 1 75  ? 129.269 98.622  119.516 1.00 141.58 ? 75  GLN B C   1 
ATOM   2525 O  O   . GLN B 1 75  ? 129.615 98.797  120.690 1.00 148.30 ? 75  GLN B O   1 
ATOM   2526 C  CB  . GLN B 1 75  ? 130.870 97.568  117.909 1.00 143.51 ? 75  GLN B CB  1 
ATOM   2527 C  CG  . GLN B 1 75  ? 131.302 96.368  117.098 1.00 144.79 ? 75  GLN B CG  1 
ATOM   2528 C  CD  . GLN B 1 75  ? 132.699 96.527  116.537 1.00 146.68 ? 75  GLN B CD  1 
ATOM   2529 O  OE1 . GLN B 1 75  ? 133.143 97.640  116.254 1.00 147.83 ? 75  GLN B OE1 1 
ATOM   2530 N  NE2 . GLN B 1 75  ? 133.403 95.414  116.378 1.00 144.00 ? 75  GLN B NE2 1 
ATOM   2531 N  N   . LEU B 1 76  ? 128.573 99.535  118.837 1.00 129.53 ? 76  LEU B N   1 
ATOM   2532 C  CA  . LEU B 1 76  ? 128.151 100.764 119.498 1.00 128.17 ? 76  LEU B CA  1 
ATOM   2533 C  C   . LEU B 1 76  ? 127.184 100.484 120.639 1.00 129.83 ? 76  LEU B C   1 
ATOM   2534 O  O   . LEU B 1 76  ? 127.281 101.116 121.695 1.00 133.80 ? 76  LEU B O   1 
ATOM   2535 C  CB  . LEU B 1 76  ? 127.525 101.721 118.487 1.00 131.66 ? 76  LEU B CB  1 
ATOM   2536 C  CG  . LEU B 1 76  ? 128.515 102.571 117.692 1.00 131.58 ? 76  LEU B CG  1 
ATOM   2537 C  CD1 . LEU B 1 76  ? 127.795 103.385 116.634 1.00 129.82 ? 76  LEU B CD1 1 
ATOM   2538 C  CD2 . LEU B 1 76  ? 129.300 103.475 118.618 1.00 133.00 ? 76  LEU B CD2 1 
ATOM   2539 N  N   . TYR B 1 77  ? 126.255 99.542  120.454 1.00 133.55 ? 77  TYR B N   1 
ATOM   2540 C  CA  . TYR B 1 77  ? 125.348 99.172  121.536 1.00 132.73 ? 77  TYR B CA  1 
ATOM   2541 C  C   . TYR B 1 77  ? 126.111 98.630  122.737 1.00 135.90 ? 77  TYR B C   1 
ATOM   2542 O  O   . TYR B 1 77  ? 125.849 99.027  123.880 1.00 137.85 ? 77  TYR B O   1 
ATOM   2543 C  CB  . TYR B 1 77  ? 124.344 98.130  121.046 1.00 136.51 ? 77  TYR B CB  1 
ATOM   2544 C  CG  . TYR B 1 77  ? 123.233 98.680  120.188 1.00 139.89 ? 77  TYR B CG  1 
ATOM   2545 C  CD1 . TYR B 1 77  ? 122.775 99.976  120.357 1.00 138.86 ? 77  TYR B CD1 1 
ATOM   2546 C  CD2 . TYR B 1 77  ? 122.641 97.898  119.208 1.00 138.99 ? 77  TYR B CD2 1 
ATOM   2547 C  CE1 . TYR B 1 77  ? 121.759 100.479 119.574 1.00 138.91 ? 77  TYR B CE1 1 
ATOM   2548 C  CE2 . TYR B 1 77  ? 121.625 98.393  118.419 1.00 138.98 ? 77  TYR B CE2 1 
ATOM   2549 C  CZ  . TYR B 1 77  ? 121.188 99.684  118.607 1.00 141.93 ? 77  TYR B CZ  1 
ATOM   2550 O  OH  . TYR B 1 77  ? 120.174 100.182 117.823 1.00 144.83 ? 77  TYR B OH  1 
ATOM   2551 N  N   . ALA B 1 78  ? 127.055 97.718  122.496 1.00 124.75 ? 78  ALA B N   1 
ATOM   2552 C  CA  . ALA B 1 78  ? 127.813 97.132  123.597 1.00 123.16 ? 78  ALA B CA  1 
ATOM   2553 C  C   . ALA B 1 78  ? 128.631 98.192  124.323 1.00 126.57 ? 78  ALA B C   1 
ATOM   2554 O  O   . ALA B 1 78  ? 128.669 98.228  125.560 1.00 134.03 ? 78  ALA B O   1 
ATOM   2555 C  CB  . ALA B 1 78  ? 128.716 96.017  123.074 1.00 124.72 ? 78  ALA B CB  1 
ATOM   2556 N  N   . ALA B 1 79  ? 129.292 99.069  123.565 1.00 119.55 ? 79  ALA B N   1 
ATOM   2557 C  CA  . ALA B 1 79  ? 130.104 100.113 124.175 1.00 118.02 ? 79  ALA B CA  1 
ATOM   2558 C  C   . ALA B 1 79  ? 129.245 101.073 124.985 1.00 120.50 ? 79  ALA B C   1 
ATOM   2559 O  O   . ALA B 1 79  ? 129.626 101.484 126.086 1.00 126.09 ? 79  ALA B O   1 
ATOM   2560 C  CB  . ALA B 1 79  ? 130.888 100.859 123.098 1.00 119.28 ? 79  ALA B CB  1 
ATOM   2561 N  N   . CYS B 1 80  ? 128.076 101.442 124.455 1.00 125.93 ? 80  CYS B N   1 
ATOM   2562 C  CA  . CYS B 1 80  ? 127.176 102.316 125.196 1.00 122.30 ? 80  CYS B CA  1 
ATOM   2563 C  C   . CYS B 1 80  ? 126.705 101.668 126.486 1.00 123.57 ? 80  CYS B C   1 
ATOM   2564 O  O   . CYS B 1 80  ? 126.669 102.327 127.529 1.00 131.61 ? 80  CYS B O   1 
ATOM   2565 C  CB  . CYS B 1 80  ? 125.975 102.698 124.333 1.00 127.55 ? 80  CYS B CB  1 
ATOM   2566 S  SG  . CYS B 1 80  ? 126.081 104.329 123.582 1.00 134.84 ? 80  CYS B SG  1 
ATOM   2567 N  N   . ALA B 1 81  ? 126.348 100.385 126.444 1.00 114.69 ? 81  ALA B N   1 
ATOM   2568 C  CA  . ALA B 1 81  ? 125.900 99.700  127.650 1.00 115.47 ? 81  ALA B CA  1 
ATOM   2569 C  C   . ALA B 1 81  ? 127.005 99.664  128.697 1.00 118.14 ? 81  ALA B C   1 
ATOM   2570 O  O   . ALA B 1 81  ? 126.771 99.980  129.872 1.00 120.12 ? 81  ALA B O   1 
ATOM   2571 C  CB  . ALA B 1 81  ? 125.437 98.281  127.321 1.00 116.99 ? 81  ALA B CB  1 
ATOM   2572 N  N   . VAL B 1 82  ? 128.217 99.295  128.274 1.00 122.02 ? 82  VAL B N   1 
ATOM   2573 C  CA  . VAL B 1 82  ? 129.334 99.204  129.210 1.00 120.14 ? 82  VAL B CA  1 
ATOM   2574 C  C   . VAL B 1 82  ? 129.653 100.560 129.816 1.00 121.59 ? 82  VAL B C   1 
ATOM   2575 O  O   . VAL B 1 82  ? 129.832 100.681 131.036 1.00 124.90 ? 82  VAL B O   1 
ATOM   2576 C  CB  . VAL B 1 82  ? 130.565 98.600  128.507 1.00 117.88 ? 82  VAL B CB  1 
ATOM   2577 C  CG1 . VAL B 1 82  ? 131.792 98.732  129.385 1.00 120.56 ? 82  VAL B CG1 1 
ATOM   2578 C  CG2 . VAL B 1 82  ? 130.312 97.146  128.167 1.00 118.18 ? 82  VAL B CG2 1 
ATOM   2579 N  N   . CYS B 1 83  ? 129.716 101.603 128.988 1.00 125.24 ? 83  CYS B N   1 
ATOM   2580 C  CA  . CYS B 1 83  ? 130.039 102.928 129.498 1.00 123.24 ? 83  CYS B CA  1 
ATOM   2581 C  C   . CYS B 1 83  ? 128.937 103.469 130.400 1.00 124.14 ? 83  CYS B C   1 
ATOM   2582 O  O   . CYS B 1 83  ? 129.228 104.154 131.383 1.00 131.52 ? 83  CYS B O   1 
ATOM   2583 C  CB  . CYS B 1 83  ? 130.310 103.884 128.339 1.00 125.70 ? 83  CYS B CB  1 
ATOM   2584 S  SG  . CYS B 1 83  ? 131.906 103.643 127.535 1.00 138.85 ? 83  CYS B SG  1 
ATOM   2585 N  N   . PHE B 1 84  ? 127.671 103.173 130.096 1.00 122.28 ? 84  PHE B N   1 
ATOM   2586 C  CA  . PHE B 1 84  ? 126.588 103.612 130.969 1.00 123.06 ? 84  PHE B CA  1 
ATOM   2587 C  C   . PHE B 1 84  ? 126.657 102.925 132.326 1.00 121.30 ? 84  PHE B C   1 
ATOM   2588 O  O   . PHE B 1 84  ? 126.449 103.564 133.364 1.00 120.69 ? 84  PHE B O   1 
ATOM   2589 C  CB  . PHE B 1 84  ? 125.236 103.352 130.310 1.00 124.39 ? 84  PHE B CB  1 
ATOM   2590 C  CG  . PHE B 1 84  ? 124.075 103.907 131.081 1.00 125.50 ? 84  PHE B CG  1 
ATOM   2591 C  CD1 . PHE B 1 84  ? 123.695 105.227 130.927 1.00 126.48 ? 84  PHE B CD1 1 
ATOM   2592 C  CD2 . PHE B 1 84  ? 123.369 103.111 131.966 1.00 124.57 ? 84  PHE B CD2 1 
ATOM   2593 C  CE1 . PHE B 1 84  ? 122.631 105.741 131.636 1.00 127.55 ? 84  PHE B CE1 1 
ATOM   2594 C  CE2 . PHE B 1 84  ? 122.306 103.620 132.679 1.00 126.72 ? 84  PHE B CE2 1 
ATOM   2595 C  CZ  . PHE B 1 84  ? 121.936 104.937 132.514 1.00 126.78 ? 84  PHE B CZ  1 
ATOM   2596 N  N   . VAL B 1 85  ? 126.936 101.620 132.339 1.00 117.01 ? 85  VAL B N   1 
ATOM   2597 C  CA  . VAL B 1 85  ? 127.069 100.916 133.612 1.00 117.98 ? 85  VAL B CA  1 
ATOM   2598 C  C   . VAL B 1 85  ? 128.231 101.488 134.414 1.00 122.05 ? 85  VAL B C   1 
ATOM   2599 O  O   . VAL B 1 85  ? 128.119 101.721 135.627 1.00 123.26 ? 85  VAL B O   1 
ATOM   2600 C  CB  . VAL B 1 85  ? 127.232 99.405  133.373 1.00 116.93 ? 85  VAL B CB  1 
ATOM   2601 C  CG1 . VAL B 1 85  ? 127.652 98.707  134.651 1.00 116.43 ? 85  VAL B CG1 1 
ATOM   2602 C  CG2 . VAL B 1 85  ? 125.940 98.815  132.846 1.00 118.78 ? 85  VAL B CG2 1 
ATOM   2603 N  N   . PHE B 1 86  ? 129.359 101.735 133.745 1.00 121.67 ? 86  PHE B N   1 
ATOM   2604 C  CA  . PHE B 1 86  ? 130.513 102.326 134.416 1.00 117.70 ? 86  PHE B CA  1 
ATOM   2605 C  C   . PHE B 1 86  ? 130.178 103.699 134.986 1.00 119.49 ? 86  PHE B C   1 
ATOM   2606 O  O   . PHE B 1 86  ? 130.539 104.012 136.126 1.00 123.92 ? 86  PHE B O   1 
ATOM   2607 C  CB  . PHE B 1 86  ? 131.678 102.415 133.431 1.00 120.43 ? 86  PHE B CB  1 
ATOM   2608 C  CG  . PHE B 1 86  ? 133.019 102.588 134.080 1.00 125.15 ? 86  PHE B CG  1 
ATOM   2609 C  CD1 . PHE B 1 86  ? 133.169 102.476 135.450 1.00 128.40 ? 86  PHE B CD1 1 
ATOM   2610 C  CD2 . PHE B 1 86  ? 134.135 102.860 133.311 1.00 123.49 ? 86  PHE B CD2 1 
ATOM   2611 C  CE1 . PHE B 1 86  ? 134.404 102.639 136.038 1.00 126.23 ? 86  PHE B CE1 1 
ATOM   2612 C  CE2 . PHE B 1 86  ? 135.370 103.023 133.895 1.00 126.48 ? 86  PHE B CE2 1 
ATOM   2613 C  CZ  . PHE B 1 86  ? 135.505 102.912 135.259 1.00 126.87 ? 86  PHE B CZ  1 
ATOM   2614 N  N   . MET B 1 87  ? 129.480 104.528 134.208 1.00 120.43 ? 87  MET B N   1 
ATOM   2615 C  CA  . MET B 1 87  ? 129.119 105.862 134.670 1.00 117.89 ? 87  MET B CA  1 
ATOM   2616 C  C   . MET B 1 87  ? 128.194 105.801 135.875 1.00 123.50 ? 87  MET B C   1 
ATOM   2617 O  O   . MET B 1 87  ? 128.365 106.561 136.833 1.00 127.54 ? 87  MET B O   1 
ATOM   2618 C  CB  . MET B 1 87  ? 128.460 106.646 133.538 1.00 118.78 ? 87  MET B CB  1 
ATOM   2619 C  CG  . MET B 1 87  ? 127.778 107.917 133.993 1.00 119.66 ? 87  MET B CG  1 
ATOM   2620 S  SD  . MET B 1 87  ? 126.858 108.720 132.673 1.00 134.51 ? 87  MET B SD  1 
ATOM   2621 C  CE  . MET B 1 87  ? 125.288 107.874 132.800 1.00 128.40 ? 87  MET B CE  1 
ATOM   2622 N  N   . ALA B 1 88  ? 127.200 104.912 135.844 1.00 122.83 ? 88  ALA B N   1 
ATOM   2623 C  CA  . ALA B 1 88  ? 126.284 104.796 136.974 1.00 119.09 ? 88  ALA B CA  1 
ATOM   2624 C  C   . ALA B 1 88  ? 127.019 104.346 138.230 1.00 122.38 ? 88  ALA B C   1 
ATOM   2625 O  O   . ALA B 1 88  ? 126.817 104.906 139.318 1.00 128.20 ? 88  ALA B O   1 
ATOM   2626 C  CB  . ALA B 1 88  ? 125.152 103.828 136.636 1.00 119.84 ? 88  ALA B CB  1 
ATOM   2627 N  N   . GLY B 1 89  ? 127.886 103.342 138.097 1.00 113.58 ? 89  GLY B N   1 
ATOM   2628 C  CA  . GLY B 1 89  ? 128.653 102.891 139.245 1.00 113.25 ? 89  GLY B CA  1 
ATOM   2629 C  C   . GLY B 1 89  ? 129.541 103.977 139.815 1.00 114.49 ? 89  GLY B C   1 
ATOM   2630 O  O   . GLY B 1 89  ? 129.629 104.148 141.034 1.00 114.58 ? 89  GLY B O   1 
ATOM   2631 N  N   . GLU B 1 90  ? 130.202 104.739 138.940 1.00 124.33 ? 90  GLU B N   1 
ATOM   2632 C  CA  . GLU B 1 90  ? 131.091 105.790 139.419 1.00 120.81 ? 90  GLU B CA  1 
ATOM   2633 C  C   . GLU B 1 90  ? 130.312 106.932 140.057 1.00 121.92 ? 90  GLU B C   1 
ATOM   2634 O  O   . GLU B 1 90  ? 130.768 107.518 141.043 1.00 127.59 ? 90  GLU B O   1 
ATOM   2635 C  CB  . GLU B 1 90  ? 131.968 106.303 138.282 1.00 120.93 ? 90  GLU B CB  1 
ATOM   2636 C  CG  . GLU B 1 90  ? 133.439 106.024 138.506 1.00 123.68 ? 90  GLU B CG  1 
ATOM   2637 C  CD  . GLU B 1 90  ? 134.331 106.802 137.570 1.00 129.80 ? 90  GLU B CD  1 
ATOM   2638 O  OE1 . GLU B 1 90  ? 135.518 106.994 137.908 1.00 130.40 ? 90  GLU B OE1 1 
ATOM   2639 O  OE2 . GLU B 1 90  ? 133.846 107.226 136.502 1.00 129.16 ? 90  GLU B OE2 1 
ATOM   2640 N  N   . VAL B 1 91  ? 129.139 107.266 139.515 1.00 122.53 ? 91  VAL B N   1 
ATOM   2641 C  CA  . VAL B 1 91  ? 128.309 108.290 140.141 1.00 124.41 ? 91  VAL B CA  1 
ATOM   2642 C  C   . VAL B 1 91  ? 127.886 107.853 141.532 1.00 123.50 ? 91  VAL B C   1 
ATOM   2643 O  O   . VAL B 1 91  ? 127.966 108.635 142.488 1.00 126.82 ? 91  VAL B O   1 
ATOM   2644 C  CB  . VAL B 1 91  ? 127.086 108.615 139.263 1.00 125.16 ? 91  VAL B CB  1 
ATOM   2645 C  CG1 . VAL B 1 91  ? 126.054 109.383 140.064 1.00 122.66 ? 91  VAL B CG1 1 
ATOM   2646 C  CG2 . VAL B 1 91  ? 127.502 109.419 138.053 1.00 126.49 ? 91  VAL B CG2 1 
ATOM   2647 N  N   . VAL B 1 92  ? 127.447 106.602 141.677 1.00 109.96 ? 92  VAL B N   1 
ATOM   2648 C  CA  . VAL B 1 92  ? 127.040 106.109 142.990 1.00 108.39 ? 92  VAL B CA  1 
ATOM   2649 C  C   . VAL B 1 92  ? 128.213 106.161 143.962 1.00 115.50 ? 92  VAL B C   1 
ATOM   2650 O  O   . VAL B 1 92  ? 128.086 106.642 145.095 1.00 121.75 ? 92  VAL B O   1 
ATOM   2651 C  CB  . VAL B 1 92  ? 126.465 104.687 142.877 1.00 113.78 ? 92  VAL B CB  1 
ATOM   2652 C  CG1 . VAL B 1 92  ? 126.348 104.050 144.249 1.00 112.20 ? 92  VAL B CG1 1 
ATOM   2653 C  CG2 . VAL B 1 92  ? 125.116 104.719 142.184 1.00 117.57 ? 92  VAL B CG2 1 
ATOM   2654 N  N   . GLY B 1 93  ? 129.380 105.683 143.524 1.00 121.44 ? 93  GLY B N   1 
ATOM   2655 C  CA  . GLY B 1 93  ? 130.538 105.669 144.404 1.00 119.88 ? 93  GLY B CA  1 
ATOM   2656 C  C   . GLY B 1 93  ? 130.985 107.056 144.821 1.00 119.41 ? 93  GLY B C   1 
ATOM   2657 O  O   . GLY B 1 93  ? 131.276 107.300 145.994 1.00 124.47 ? 93  GLY B O   1 
ATOM   2658 N  N   . GLY B 1 94  ? 131.041 107.987 143.868 1.00 115.67 ? 94  GLY B N   1 
ATOM   2659 C  CA  . GLY B 1 94  ? 131.455 109.338 144.195 1.00 111.86 ? 94  GLY B CA  1 
ATOM   2660 C  C   . GLY B 1 94  ? 130.465 110.057 145.087 1.00 118.67 ? 94  GLY B C   1 
ATOM   2661 O  O   . GLY B 1 94  ? 130.859 110.808 145.983 1.00 127.72 ? 94  GLY B O   1 
ATOM   2662 N  N   . TYR B 1 95  ? 129.166 109.849 144.854 1.00 126.89 ? 95  TYR B N   1 
ATOM   2663 C  CA  . TYR B 1 95  ? 128.167 110.425 145.746 1.00 123.11 ? 95  TYR B CA  1 
ATOM   2664 C  C   . TYR B 1 95  ? 128.312 109.867 147.153 1.00 122.05 ? 95  TYR B C   1 
ATOM   2665 O  O   . TYR B 1 95  ? 128.186 110.604 148.137 1.00 120.61 ? 95  TYR B O   1 
ATOM   2666 C  CB  . TYR B 1 95  ? 126.761 110.165 145.212 1.00 125.32 ? 95  TYR B CB  1 
ATOM   2667 C  CG  . TYR B 1 95  ? 125.673 110.727 146.097 1.00 130.54 ? 95  TYR B CG  1 
ATOM   2668 C  CD1 . TYR B 1 95  ? 124.981 109.912 146.983 1.00 130.49 ? 95  TYR B CD1 1 
ATOM   2669 C  CD2 . TYR B 1 95  ? 125.343 112.075 146.055 1.00 127.56 ? 95  TYR B CD2 1 
ATOM   2670 C  CE1 . TYR B 1 95  ? 123.991 110.421 147.796 1.00 131.57 ? 95  TYR B CE1 1 
ATOM   2671 C  CE2 . TYR B 1 95  ? 124.353 112.593 146.866 1.00 128.14 ? 95  TYR B CE2 1 
ATOM   2672 C  CZ  . TYR B 1 95  ? 123.681 111.761 147.734 1.00 134.25 ? 95  TYR B CZ  1 
ATOM   2673 O  OH  . TYR B 1 95  ? 122.694 112.272 148.544 1.00 134.14 ? 95  TYR B OH  1 
ATOM   2674 N  N   . LEU B 1 96  ? 128.575 108.565 147.269 1.00 119.20 ? 96  LEU B N   1 
ATOM   2675 C  CA  . LEU B 1 96  ? 128.811 107.987 148.586 1.00 121.01 ? 96  LEU B CA  1 
ATOM   2676 C  C   . LEU B 1 96  ? 130.067 108.558 149.229 1.00 122.21 ? 96  LEU B C   1 
ATOM   2677 O  O   . LEU B 1 96  ? 130.130 108.690 150.456 1.00 125.16 ? 96  LEU B O   1 
ATOM   2678 C  CB  . LEU B 1 96  ? 128.912 106.467 148.481 1.00 122.48 ? 96  LEU B CB  1 
ATOM   2679 C  CG  . LEU B 1 96  ? 127.692 105.676 148.947 1.00 121.89 ? 96  LEU B CG  1 
ATOM   2680 C  CD1 . LEU B 1 96  ? 126.425 106.251 148.347 1.00 119.89 ? 96  LEU B CD1 1 
ATOM   2681 C  CD2 . LEU B 1 96  ? 127.843 104.212 148.582 1.00 121.47 ? 96  LEU B CD2 1 
ATOM   2682 N  N   . ALA B 1 97  ? 131.072 108.899 148.426 1.00 125.27 ? 97  ALA B N   1 
ATOM   2683 C  CA  . ALA B 1 97  ? 132.332 109.414 148.945 1.00 123.28 ? 97  ALA B CA  1 
ATOM   2684 C  C   . ALA B 1 97  ? 132.390 110.934 149.014 1.00 120.64 ? 97  ALA B C   1 
ATOM   2685 O  O   . ALA B 1 97  ? 133.381 111.471 149.516 1.00 120.93 ? 97  ALA B O   1 
ATOM   2686 C  CB  . ALA B 1 97  ? 133.497 108.908 148.092 1.00 121.20 ? 97  ALA B CB  1 
ATOM   2687 N  N   . HIS B 1 98  ? 131.364 111.633 148.526 1.00 124.04 ? 98  HIS B N   1 
ATOM   2688 C  CA  . HIS B 1 98  ? 131.349 113.098 148.489 1.00 123.84 ? 98  HIS B CA  1 
ATOM   2689 C  C   . HIS B 1 98  ? 132.565 113.649 147.749 1.00 127.45 ? 98  HIS B C   1 
ATOM   2690 O  O   . HIS B 1 98  ? 133.114 114.692 148.110 1.00 131.49 ? 98  HIS B O   1 
ATOM   2691 C  CB  . HIS B 1 98  ? 131.262 113.694 149.896 1.00 125.30 ? 98  HIS B CB  1 
ATOM   2692 C  CG  . HIS B 1 98  ? 130.212 113.066 150.757 1.00 130.82 ? 98  HIS B CG  1 
ATOM   2693 N  ND1 . HIS B 1 98  ? 130.479 112.582 152.019 1.00 131.59 ? 98  HIS B ND1 1 
ATOM   2694 C  CD2 . HIS B 1 98  ? 128.894 112.848 150.541 1.00 131.53 ? 98  HIS B CD2 1 
ATOM   2695 C  CE1 . HIS B 1 98  ? 129.371 112.089 152.542 1.00 130.67 ? 98  HIS B CE1 1 
ATOM   2696 N  NE2 . HIS B 1 98  ? 128.395 112.238 151.666 1.00 134.69 ? 98  HIS B NE2 1 
ATOM   2697 N  N   . SER B 1 99  ? 132.984 112.952 146.700 1.00 121.59 ? 99  SER B N   1 
ATOM   2698 C  CA  . SER B 1 99  ? 134.173 113.314 145.948 1.00 113.73 ? 99  SER B CA  1 
ATOM   2699 C  C   . SER B 1 99  ? 133.795 114.011 144.649 1.00 116.51 ? 99  SER B C   1 
ATOM   2700 O  O   . SER B 1 99  ? 132.769 113.710 144.036 1.00 122.24 ? 99  SER B O   1 
ATOM   2701 C  CB  . SER B 1 99  ? 135.019 112.079 145.642 1.00 114.37 ? 99  SER B CB  1 
ATOM   2702 O  OG  . SER B 1 99  ? 136.317 112.449 145.221 1.00 120.95 ? 99  SER B OG  1 
ATOM   2703 N  N   . LEU B 1 100 ? 134.639 114.954 144.234 1.00 110.74 ? 100 LEU B N   1 
ATOM   2704 C  CA  . LEU B 1 100 ? 134.424 115.677 142.991 1.00 112.98 ? 100 LEU B CA  1 
ATOM   2705 C  C   . LEU B 1 100 ? 135.295 115.179 141.848 1.00 117.19 ? 100 LEU B C   1 
ATOM   2706 O  O   . LEU B 1 100 ? 134.930 115.375 140.685 1.00 123.35 ? 100 LEU B O   1 
ATOM   2707 C  CB  . LEU B 1 100 ? 134.672 117.174 143.194 1.00 112.33 ? 100 LEU B CB  1 
ATOM   2708 C  CG  . LEU B 1 100 ? 133.480 117.992 143.690 1.00 113.02 ? 100 LEU B CG  1 
ATOM   2709 C  CD1 . LEU B 1 100 ? 133.782 119.472 143.591 1.00 116.36 ? 100 LEU B CD1 1 
ATOM   2710 C  CD2 . LEU B 1 100 ? 132.230 117.648 142.906 1.00 112.11 ? 100 LEU B CD2 1 
ATOM   2711 N  N   . ALA B 1 101 ? 136.437 114.556 142.144 1.00 110.57 ? 101 ALA B N   1 
ATOM   2712 C  CA  . ALA B 1 101 ? 137.229 113.939 141.087 1.00 111.33 ? 101 ALA B CA  1 
ATOM   2713 C  C   . ALA B 1 101 ? 136.470 112.788 140.441 1.00 118.50 ? 101 ALA B C   1 
ATOM   2714 O  O   . ALA B 1 101 ? 136.496 112.619 139.215 1.00 123.34 ? 101 ALA B O   1 
ATOM   2715 C  CB  . ALA B 1 101 ? 138.564 113.457 141.648 1.00 112.36 ? 101 ALA B CB  1 
ATOM   2716 N  N   . ILE B 1 102 ? 135.784 111.985 141.256 1.00 113.95 ? 102 ILE B N   1 
ATOM   2717 C  CA  . ILE B 1 102 ? 134.955 110.913 140.722 1.00 110.12 ? 102 ILE B CA  1 
ATOM   2718 C  C   . ILE B 1 102 ? 133.798 111.483 139.918 1.00 115.03 ? 102 ILE B C   1 
ATOM   2719 O  O   . ILE B 1 102 ? 133.382 110.894 138.915 1.00 123.31 ? 102 ILE B O   1 
ATOM   2720 C  CB  . ILE B 1 102 ? 134.474 110.002 141.865 1.00 111.14 ? 102 ILE B CB  1 
ATOM   2721 C  CG1 . ILE B 1 102 ? 135.647 109.669 142.784 1.00 106.77 ? 102 ILE B CG1 1 
ATOM   2722 C  CG2 . ILE B 1 102 ? 133.862 108.734 141.311 1.00 118.20 ? 102 ILE B CG2 1 
ATOM   2723 C  CD1 . ILE B 1 102 ? 135.357 108.578 143.775 1.00 115.61 ? 102 ILE B CD1 1 
ATOM   2724 N  N   . MET B 1 103 ? 133.260 112.631 140.333 1.00 117.95 ? 103 MET B N   1 
ATOM   2725 C  CA  . MET B 1 103 ? 132.307 113.343 139.488 1.00 115.67 ? 103 MET B CA  1 
ATOM   2726 C  C   . MET B 1 103 ? 132.921 113.726 138.151 1.00 117.25 ? 103 MET B C   1 
ATOM   2727 O  O   . MET B 1 103 ? 132.249 113.663 137.120 1.00 128.83 ? 103 MET B O   1 
ATOM   2728 C  CB  . MET B 1 103 ? 131.776 114.581 140.206 1.00 125.46 ? 103 MET B CB  1 
ATOM   2729 C  CG  . MET B 1 103 ? 130.846 114.298 141.362 1.00 127.30 ? 103 MET B CG  1 
ATOM   2730 S  SD  . MET B 1 103 ? 129.692 112.985 140.934 1.00 139.26 ? 103 MET B SD  1 
ATOM   2731 C  CE  . MET B 1 103 ? 130.151 111.734 142.115 1.00 124.98 ? 103 MET B CE  1 
ATOM   2732 N  N   . THR B 1 104 ? 134.188 114.138 138.142 1.00 112.92 ? 104 THR B N   1 
ATOM   2733 C  CA  . THR B 1 104 ? 134.822 114.480 136.873 1.00 118.38 ? 104 THR B CA  1 
ATOM   2734 C  C   . THR B 1 104 ? 134.953 113.258 135.973 1.00 125.22 ? 104 THR B C   1 
ATOM   2735 O  O   . THR B 1 104 ? 134.674 113.330 134.768 1.00 127.48 ? 104 THR B O   1 
ATOM   2736 C  CB  . THR B 1 104 ? 136.189 115.113 137.118 1.00 122.29 ? 104 THR B CB  1 
ATOM   2737 O  OG1 . THR B 1 104 ? 136.083 116.091 138.158 1.00 129.78 ? 104 THR B OG1 1 
ATOM   2738 C  CG2 . THR B 1 104 ? 136.686 115.787 135.857 1.00 123.01 ? 104 THR B CG2 1 
ATOM   2739 N  N   . ASP B 1 105 ? 135.365 112.123 136.539 1.00 125.60 ? 105 ASP B N   1 
ATOM   2740 C  CA  . ASP B 1 105 ? 135.469 110.903 135.744 1.00 117.14 ? 105 ASP B CA  1 
ATOM   2741 C  C   . ASP B 1 105 ? 134.105 110.460 135.228 1.00 120.32 ? 105 ASP B C   1 
ATOM   2742 O  O   . ASP B 1 105 ? 133.971 110.047 134.069 1.00 125.49 ? 105 ASP B O   1 
ATOM   2743 C  CB  . ASP B 1 105 ? 136.117 109.796 136.571 1.00 118.75 ? 105 ASP B CB  1 
ATOM   2744 C  CG  . ASP B 1 105 ? 137.208 109.071 135.815 1.00 130.65 ? 105 ASP B CG  1 
ATOM   2745 O  OD1 . ASP B 1 105 ? 137.685 108.029 136.310 1.00 134.93 ? 105 ASP B OD1 1 
ATOM   2746 O  OD2 . ASP B 1 105 ? 137.588 109.539 134.722 1.00 133.21 ? 105 ASP B OD2 1 
ATOM   2747 N  N   . ALA B 1 106 ? 133.079 110.543 136.074 1.00 116.57 ? 106 ALA B N   1 
ATOM   2748 C  CA  . ALA B 1 106 ? 131.733 110.181 135.650 1.00 112.68 ? 106 ALA B CA  1 
ATOM   2749 C  C   . ALA B 1 106 ? 131.216 111.131 134.579 1.00 112.46 ? 106 ALA B C   1 
ATOM   2750 O  O   . ALA B 1 106 ? 130.486 110.715 133.678 1.00 119.12 ? 106 ALA B O   1 
ATOM   2751 C  CB  . ALA B 1 106 ? 130.796 110.163 136.854 1.00 110.36 ? 106 ALA B CB  1 
ATOM   2752 N  N   . ALA B 1 107 ? 131.577 112.410 134.664 1.00 108.16 ? 107 ALA B N   1 
ATOM   2753 C  CA  . ALA B 1 107 ? 131.204 113.357 133.621 1.00 107.19 ? 107 ALA B CA  1 
ATOM   2754 C  C   . ALA B 1 107 ? 131.883 113.015 132.304 1.00 114.55 ? 107 ALA B C   1 
ATOM   2755 O  O   . ALA B 1 107 ? 131.276 113.140 131.235 1.00 118.56 ? 107 ALA B O   1 
ATOM   2756 C  CB  . ALA B 1 107 ? 131.556 114.778 134.054 1.00 108.16 ? 107 ALA B CB  1 
ATOM   2757 N  N   . HIS B 1 108 ? 133.146 112.591 132.357 1.00 113.21 ? 108 HIS B N   1 
ATOM   2758 C  CA  . HIS B 1 108 ? 133.809 112.151 131.135 1.00 113.97 ? 108 HIS B CA  1 
ATOM   2759 C  C   . HIS B 1 108 ? 133.120 110.926 130.547 1.00 116.35 ? 108 HIS B C   1 
ATOM   2760 O  O   . HIS B 1 108 ? 132.945 110.825 129.326 1.00 118.66 ? 108 HIS B O   1 
ATOM   2761 C  CB  . HIS B 1 108 ? 135.280 111.849 131.400 1.00 113.18 ? 108 HIS B CB  1 
ATOM   2762 C  CG  . HIS B 1 108 ? 135.960 111.164 130.259 1.00 116.07 ? 108 HIS B CG  1 
ATOM   2763 N  ND1 . HIS B 1 108 ? 136.040 111.722 129.001 1.00 117.98 ? 108 HIS B ND1 1 
ATOM   2764 C  CD2 . HIS B 1 108 ? 136.579 109.965 130.178 1.00 114.13 ? 108 HIS B CD2 1 
ATOM   2765 C  CE1 . HIS B 1 108 ? 136.685 110.897 128.197 1.00 114.70 ? 108 HIS B CE1 1 
ATOM   2766 N  NE2 . HIS B 1 108 ? 137.025 109.825 128.887 1.00 119.72 ? 108 HIS B NE2 1 
ATOM   2767 N  N   . LEU B 1 109 ? 132.729 109.980 131.401 1.00 115.15 ? 109 LEU B N   1 
ATOM   2768 C  CA  . LEU B 1 109 ? 132.002 108.810 130.919 1.00 109.02 ? 109 LEU B CA  1 
ATOM   2769 C  C   . LEU B 1 109 ? 130.658 109.204 130.323 1.00 111.97 ? 109 LEU B C   1 
ATOM   2770 O  O   . LEU B 1 109 ? 130.209 108.614 129.335 1.00 117.46 ? 109 LEU B O   1 
ATOM   2771 C  CB  . LEU B 1 109 ? 131.810 107.804 132.049 1.00 106.19 ? 109 LEU B CB  1 
ATOM   2772 C  CG  . LEU B 1 109 ? 133.004 106.892 132.312 1.00 107.81 ? 109 LEU B CG  1 
ATOM   2773 C  CD1 . LEU B 1 109 ? 132.803 106.132 133.603 1.00 112.83 ? 109 LEU B CD1 1 
ATOM   2774 C  CD2 . LEU B 1 109 ? 133.205 105.941 131.150 1.00 109.19 ? 109 LEU B CD2 1 
ATOM   2775 N  N   . LEU B 1 110 ? 129.994 110.193 130.921 1.00 115.44 ? 110 LEU B N   1 
ATOM   2776 C  CA  . LEU B 1 110 ? 128.745 110.699 130.366 1.00 111.08 ? 110 LEU B CA  1 
ATOM   2777 C  C   . LEU B 1 110 ? 128.974 111.318 128.997 1.00 113.29 ? 110 LEU B C   1 
ATOM   2778 O  O   . LEU B 1 110 ? 128.152 111.158 128.091 1.00 113.99 ? 110 LEU B O   1 
ATOM   2779 C  CB  . LEU B 1 110 ? 128.126 111.715 131.329 1.00 114.83 ? 110 LEU B CB  1 
ATOM   2780 C  CG  . LEU B 1 110 ? 126.657 112.131 131.195 1.00 120.63 ? 110 LEU B CG  1 
ATOM   2781 C  CD1 . LEU B 1 110 ? 126.189 112.753 132.497 1.00 114.80 ? 110 LEU B CD1 1 
ATOM   2782 C  CD2 . LEU B 1 110 ? 126.434 113.111 130.055 1.00 116.88 ? 110 LEU B CD2 1 
ATOM   2783 N  N   . ALA B 1 111 ? 130.081 112.041 128.832 1.00 115.85 ? 111 ALA B N   1 
ATOM   2784 C  CA  . ALA B 1 111 ? 130.413 112.593 127.524 1.00 114.06 ? 111 ALA B CA  1 
ATOM   2785 C  C   . ALA B 1 111 ? 130.642 111.487 126.504 1.00 115.94 ? 111 ALA B C   1 
ATOM   2786 O  O   . ALA B 1 111 ? 130.186 111.582 125.358 1.00 117.86 ? 111 ALA B O   1 
ATOM   2787 C  CB  . ALA B 1 111 ? 131.645 113.489 127.629 1.00 113.70 ? 111 ALA B CB  1 
ATOM   2788 N  N   . ASP B 1 112 ? 131.350 110.429 126.903 1.00 126.01 ? 112 ASP B N   1 
ATOM   2789 C  CA  . ASP B 1 112 ? 131.573 109.298 126.006 1.00 123.83 ? 112 ASP B CA  1 
ATOM   2790 C  C   . ASP B 1 112 ? 130.250 108.655 125.601 1.00 123.77 ? 112 ASP B C   1 
ATOM   2791 O  O   . ASP B 1 112 ? 130.014 108.371 124.418 1.00 126.34 ? 112 ASP B O   1 
ATOM   2792 C  CB  . ASP B 1 112 ? 132.492 108.275 126.679 1.00 123.08 ? 112 ASP B CB  1 
ATOM   2793 C  CG  . ASP B 1 112 ? 133.945 108.720 126.707 1.00 131.52 ? 112 ASP B CG  1 
ATOM   2794 O  OD1 . ASP B 1 112 ? 134.202 109.906 126.420 1.00 135.61 ? 112 ASP B OD1 1 
ATOM   2795 O  OD2 . ASP B 1 112 ? 134.831 107.897 127.034 1.00 133.12 ? 112 ASP B OD2 1 
ATOM   2796 N  N   . VAL B 1 113 ? 129.365 108.441 126.577 1.00 120.76 ? 113 VAL B N   1 
ATOM   2797 C  CA  . VAL B 1 113 ? 128.062 107.839 126.306 1.00 115.75 ? 113 VAL B CA  1 
ATOM   2798 C  C   . VAL B 1 113 ? 127.251 108.722 125.372 1.00 118.58 ? 113 VAL B C   1 
ATOM   2799 O  O   . VAL B 1 113 ? 126.615 108.235 124.433 1.00 123.65 ? 113 VAL B O   1 
ATOM   2800 C  CB  . VAL B 1 113 ? 127.310 107.575 127.623 1.00 118.27 ? 113 VAL B CB  1 
ATOM   2801 C  CG1 . VAL B 1 113 ? 125.812 107.536 127.386 1.00 116.30 ? 113 VAL B CG1 1 
ATOM   2802 C  CG2 . VAL B 1 113 ? 127.770 106.280 128.246 1.00 118.78 ? 113 VAL B CG2 1 
ATOM   2803 N  N   . GLY B 1 114 ? 127.247 110.031 125.622 1.00 122.01 ? 114 GLY B N   1 
ATOM   2804 C  CA  . GLY B 1 114 ? 126.497 110.935 124.771 1.00 117.74 ? 114 GLY B CA  1 
ATOM   2805 C  C   . GLY B 1 114 ? 127.024 110.969 123.352 1.00 116.41 ? 114 GLY B C   1 
ATOM   2806 O  O   . GLY B 1 114 ? 126.250 111.007 122.396 1.00 117.85 ? 114 GLY B O   1 
ATOM   2807 N  N   . SER B 1 115 ? 128.348 110.952 123.194 1.00 119.87 ? 115 SER B N   1 
ATOM   2808 C  CA  . SER B 1 115 ? 128.923 110.925 121.855 1.00 122.17 ? 115 SER B CA  1 
ATOM   2809 C  C   . SER B 1 115 ? 128.543 109.647 121.119 1.00 121.92 ? 115 SER B C   1 
ATOM   2810 O  O   . SER B 1 115 ? 128.160 109.688 119.943 1.00 124.29 ? 115 SER B O   1 
ATOM   2811 C  CB  . SER B 1 115 ? 130.442 111.069 121.931 1.00 122.95 ? 115 SER B CB  1 
ATOM   2812 O  OG  . SER B 1 115 ? 131.074 109.805 121.859 1.00 125.73 ? 115 SER B OG  1 
ATOM   2813 N  N   . MET B 1 116 ? 128.624 108.499 121.797 1.00 127.29 ? 116 MET B N   1 
ATOM   2814 C  CA  . MET B 1 116 ? 128.271 107.247 121.135 1.00 125.66 ? 116 MET B CA  1 
ATOM   2815 C  C   . MET B 1 116 ? 126.782 107.186 120.813 1.00 129.17 ? 116 MET B C   1 
ATOM   2816 O  O   . MET B 1 116 ? 126.390 106.674 119.759 1.00 130.23 ? 116 MET B O   1 
ATOM   2817 C  CB  . MET B 1 116 ? 128.687 106.056 121.993 1.00 126.64 ? 116 MET B CB  1 
ATOM   2818 C  CG  . MET B 1 116 ? 130.027 105.465 121.602 1.00 124.79 ? 116 MET B CG  1 
ATOM   2819 S  SD  . MET B 1 116 ? 130.692 104.343 122.840 1.00 138.35 ? 116 MET B SD  1 
ATOM   2820 C  CE  . MET B 1 116 ? 130.318 105.225 124.347 1.00 132.49 ? 116 MET B CE  1 
ATOM   2821 N  N   . MET B 1 117 ? 125.936 107.703 121.705 1.00 135.39 ? 117 MET B N   1 
ATOM   2822 C  CA  . MET B 1 117 ? 124.501 107.719 121.443 1.00 129.18 ? 117 MET B CA  1 
ATOM   2823 C  C   . MET B 1 117 ? 124.161 108.646 120.287 1.00 130.08 ? 117 MET B C   1 
ATOM   2824 O  O   . MET B 1 117 ? 123.291 108.331 119.469 1.00 134.64 ? 117 MET B O   1 
ATOM   2825 C  CB  . MET B 1 117 ? 123.740 108.133 122.701 1.00 128.70 ? 117 MET B CB  1 
ATOM   2826 C  CG  . MET B 1 117 ? 123.376 106.977 123.611 1.00 132.81 ? 117 MET B CG  1 
ATOM   2827 S  SD  . MET B 1 117 ? 121.988 107.349 124.698 1.00 151.96 ? 117 MET B SD  1 
ATOM   2828 C  CE  . MET B 1 117 ? 122.013 109.140 124.693 1.00 133.81 ? 117 MET B CE  1 
ATOM   2829 N  N   . GLY B 1 118 ? 124.824 109.799 120.208 1.00 118.38 ? 118 GLY B N   1 
ATOM   2830 C  CA  . GLY B 1 118 ? 124.632 110.670 119.064 1.00 119.80 ? 118 GLY B CA  1 
ATOM   2831 C  C   . GLY B 1 118 ? 125.082 110.023 117.771 1.00 122.84 ? 118 GLY B C   1 
ATOM   2832 O  O   . GLY B 1 118 ? 124.442 110.183 116.731 1.00 124.80 ? 118 GLY B O   1 
ATOM   2833 N  N   . SER B 1 119 ? 126.188 109.279 117.820 1.00 124.68 ? 119 SER B N   1 
ATOM   2834 C  CA  . SER B 1 119 ? 126.634 108.549 116.639 1.00 120.09 ? 119 SER B CA  1 
ATOM   2835 C  C   . SER B 1 119 ? 125.609 107.503 116.218 1.00 118.82 ? 119 SER B C   1 
ATOM   2836 O  O   . SER B 1 119 ? 125.322 107.350 115.027 1.00 120.36 ? 119 SER B O   1 
ATOM   2837 C  CB  . SER B 1 119 ? 127.988 107.897 116.909 1.00 124.16 ? 119 SER B CB  1 
ATOM   2838 O  OG  . SER B 1 119 ? 128.252 106.875 115.967 1.00 130.76 ? 119 SER B OG  1 
ATOM   2839 N  N   . LEU B 1 120 ? 125.046 106.777 117.184 1.00 118.70 ? 120 LEU B N   1 
ATOM   2840 C  CA  . LEU B 1 120 ? 124.021 105.784 116.871 1.00 119.34 ? 120 LEU B CA  1 
ATOM   2841 C  C   . LEU B 1 120 ? 122.781 106.437 116.276 1.00 120.00 ? 120 LEU B C   1 
ATOM   2842 O  O   . LEU B 1 120 ? 122.204 105.930 115.306 1.00 123.54 ? 120 LEU B O   1 
ATOM   2843 C  CB  . LEU B 1 120 ? 123.652 105.003 118.129 1.00 119.82 ? 120 LEU B CB  1 
ATOM   2844 C  CG  . LEU B 1 120 ? 124.405 103.706 118.402 1.00 119.65 ? 120 LEU B CG  1 
ATOM   2845 C  CD1 . LEU B 1 120 ? 124.093 103.224 119.802 1.00 121.36 ? 120 LEU B CD1 1 
ATOM   2846 C  CD2 . LEU B 1 120 ? 124.039 102.652 117.378 1.00 122.94 ? 120 LEU B CD2 1 
ATOM   2847 N  N   . PHE B 1 121 ? 122.348 107.557 116.856 1.00 124.99 ? 121 PHE B N   1 
ATOM   2848 C  CA  . PHE B 1 121 ? 121.173 108.252 116.347 1.00 124.82 ? 121 PHE B CA  1 
ATOM   2849 C  C   . PHE B 1 121 ? 121.410 108.776 114.939 1.00 126.60 ? 121 PHE B C   1 
ATOM   2850 O  O   . PHE B 1 121 ? 120.527 108.688 114.081 1.00 129.64 ? 121 PHE B O   1 
ATOM   2851 C  CB  . PHE B 1 121 ? 120.794 109.393 117.288 1.00 126.31 ? 121 PHE B CB  1 
ATOM   2852 C  CG  . PHE B 1 121 ? 119.496 110.054 116.943 1.00 133.47 ? 121 PHE B CG  1 
ATOM   2853 C  CD1 . PHE B 1 121 ? 118.295 109.402 117.156 1.00 132.22 ? 121 PHE B CD1 1 
ATOM   2854 C  CD2 . PHE B 1 121 ? 119.474 111.327 116.403 1.00 131.01 ? 121 PHE B CD2 1 
ATOM   2855 C  CE1 . PHE B 1 121 ? 117.098 110.007 116.838 1.00 131.79 ? 121 PHE B CE1 1 
ATOM   2856 C  CE2 . PHE B 1 121 ? 118.280 111.938 116.083 1.00 130.29 ? 121 PHE B CE2 1 
ATOM   2857 C  CZ  . PHE B 1 121 ? 117.090 111.277 116.301 1.00 132.89 ? 121 PHE B CZ  1 
ATOM   2858 N  N   . SER B 1 122 ? 122.597 109.325 114.681 1.00 125.15 ? 122 SER B N   1 
ATOM   2859 C  CA  . SER B 1 122 ? 122.920 109.789 113.338 1.00 123.82 ? 122 SER B CA  1 
ATOM   2860 C  C   . SER B 1 122 ? 122.974 108.631 112.354 1.00 123.69 ? 122 SER B C   1 
ATOM   2861 O  O   . SER B 1 122 ? 122.544 108.768 111.205 1.00 128.91 ? 122 SER B O   1 
ATOM   2862 C  CB  . SER B 1 122 ? 124.247 110.541 113.348 1.00 126.65 ? 122 SER B CB  1 
ATOM   2863 O  OG  . SER B 1 122 ? 125.307 109.691 112.951 1.00 133.73 ? 122 SER B OG  1 
ATOM   2864 N  N   . LEU B 1 123 ? 123.512 107.487 112.778 1.00 118.76 ? 123 LEU B N   1 
ATOM   2865 C  CA  . LEU B 1 123 ? 123.550 106.319 111.906 1.00 119.26 ? 123 LEU B CA  1 
ATOM   2866 C  C   . LEU B 1 123 ? 122.147 105.847 111.559 1.00 119.29 ? 123 LEU B C   1 
ATOM   2867 O  O   . LEU B 1 123 ? 121.875 105.468 110.414 1.00 120.67 ? 123 LEU B O   1 
ATOM   2868 C  CB  . LEU B 1 123 ? 124.344 105.198 112.573 1.00 123.59 ? 123 LEU B CB  1 
ATOM   2869 C  CG  . LEU B 1 123 ? 124.911 104.121 111.652 1.00 125.32 ? 123 LEU B CG  1 
ATOM   2870 C  CD1 . LEU B 1 123 ? 126.333 103.783 112.053 1.00 120.20 ? 123 LEU B CD1 1 
ATOM   2871 C  CD2 . LEU B 1 123 ? 124.036 102.883 111.688 1.00 122.23 ? 123 LEU B CD2 1 
ATOM   2872 N  N   . TRP B 1 124 ? 121.244 105.848 112.539 1.00 120.23 ? 124 TRP B N   1 
ATOM   2873 C  CA  . TRP B 1 124 ? 119.861 105.477 112.261 1.00 120.54 ? 124 TRP B CA  1 
ATOM   2874 C  C   . TRP B 1 124 ? 119.185 106.492 111.349 1.00 123.41 ? 124 TRP B C   1 
ATOM   2875 O  O   . TRP B 1 124 ? 118.427 106.117 110.448 1.00 126.08 ? 124 TRP B O   1 
ATOM   2876 C  CB  . TRP B 1 124 ? 119.081 105.336 113.564 1.00 122.50 ? 124 TRP B CB  1 
ATOM   2877 C  CG  . TRP B 1 124 ? 117.614 105.186 113.352 1.00 126.44 ? 124 TRP B CG  1 
ATOM   2878 C  CD1 . TRP B 1 124 ? 116.974 104.131 112.776 1.00 126.93 ? 124 TRP B CD1 1 
ATOM   2879 C  CD2 . TRP B 1 124 ? 116.595 106.123 113.715 1.00 127.06 ? 124 TRP B CD2 1 
ATOM   2880 N  NE1 . TRP B 1 124 ? 115.620 104.351 112.757 1.00 128.33 ? 124 TRP B NE1 1 
ATOM   2881 C  CE2 . TRP B 1 124 ? 115.362 105.569 113.329 1.00 126.92 ? 124 TRP B CE2 1 
ATOM   2882 C  CE3 . TRP B 1 124 ? 116.607 107.377 114.331 1.00 123.51 ? 124 TRP B CE3 1 
ATOM   2883 C  CZ2 . TRP B 1 124 ? 114.153 106.224 113.536 1.00 125.60 ? 124 TRP B CZ2 1 
ATOM   2884 C  CZ3 . TRP B 1 124 ? 115.407 108.025 114.535 1.00 126.03 ? 124 TRP B CZ3 1 
ATOM   2885 C  CH2 . TRP B 1 124 ? 114.197 107.449 114.139 1.00 129.59 ? 124 TRP B CH2 1 
ATOM   2886 N  N   . LEU B 1 125 ? 119.442 107.781 111.571 1.00 120.83 ? 125 LEU B N   1 
ATOM   2887 C  CA  . LEU B 1 125 ? 118.788 108.818 110.782 1.00 115.26 ? 125 LEU B CA  1 
ATOM   2888 C  C   . LEU B 1 125 ? 119.290 108.842 109.347 1.00 119.15 ? 125 LEU B C   1 
ATOM   2889 O  O   . LEU B 1 125 ? 118.513 109.120 108.428 1.00 123.60 ? 125 LEU B O   1 
ATOM   2890 C  CB  . LEU B 1 125 ? 118.999 110.182 111.431 1.00 114.97 ? 125 LEU B CB  1 
ATOM   2891 C  CG  . LEU B 1 125 ? 117.827 110.745 112.230 1.00 116.83 ? 125 LEU B CG  1 
ATOM   2892 C  CD1 . LEU B 1 125 ? 118.012 112.231 112.456 1.00 119.85 ? 125 LEU B CD1 1 
ATOM   2893 C  CD2 . LEU B 1 125 ? 116.522 110.474 111.519 1.00 118.55 ? 125 LEU B CD2 1 
ATOM   2894 N  N   . SER B 1 126 ? 120.571 108.552 109.128 1.00 130.35 ? 126 SER B N   1 
ATOM   2895 C  CA  . SER B 1 126 ? 121.133 108.624 107.787 1.00 129.66 ? 126 SER B CA  1 
ATOM   2896 C  C   . SER B 1 126 ? 120.785 107.372 106.996 1.00 130.45 ? 126 SER B C   1 
ATOM   2897 O  O   . SER B 1 126 ? 121.638 106.792 106.319 1.00 134.07 ? 126 SER B O   1 
ATOM   2898 C  CB  . SER B 1 126 ? 122.648 108.806 107.851 1.00 132.59 ? 126 SER B CB  1 
ATOM   2899 O  OG  . SER B 1 126 ? 123.300 107.552 107.934 1.00 138.32 ? 126 SER B OG  1 
ATOM   2900 N  N   . THR B 1 127 ? 119.525 106.960 107.076 1.00 125.91 ? 127 THR B N   1 
ATOM   2901 C  CA  . THR B 1 127 ? 118.982 105.922 106.211 1.00 130.29 ? 127 THR B CA  1 
ATOM   2902 C  C   . THR B 1 127 ? 117.630 106.285 105.628 1.00 136.07 ? 127 THR B C   1 
ATOM   2903 O  O   . THR B 1 127 ? 117.189 105.618 104.686 1.00 133.84 ? 127 THR B O   1 
ATOM   2904 C  CB  . THR B 1 127 ? 118.859 104.592 106.967 1.00 131.40 ? 127 THR B CB  1 
ATOM   2905 O  OG1 . THR B 1 127 ? 118.897 103.506 106.034 1.00 134.64 ? 127 THR B OG1 1 
ATOM   2906 C  CG2 . THR B 1 127 ? 117.558 104.533 107.752 1.00 129.32 ? 127 THR B CG2 1 
ATOM   2907 N  N   . ARG B 1 128 ? 116.960 107.312 106.139 1.00 131.36 ? 128 ARG B N   1 
ATOM   2908 C  CA  . ARG B 1 128 ? 115.692 107.730 105.574 1.00 127.61 ? 128 ARG B CA  1 
ATOM   2909 C  C   . ARG B 1 128 ? 115.928 108.490 104.272 1.00 125.02 ? 128 ARG B C   1 
ATOM   2910 O  O   . ARG B 1 128 ? 116.918 109.217 104.148 1.00 126.17 ? 128 ARG B O   1 
ATOM   2911 C  CB  . ARG B 1 128 ? 114.931 108.607 106.563 1.00 123.13 ? 128 ARG B CB  1 
ATOM   2912 C  CG  . ARG B 1 128 ? 114.650 107.928 107.885 1.00 121.95 ? 128 ARG B CG  1 
ATOM   2913 C  CD  . ARG B 1 128 ? 114.476 108.943 108.992 1.00 127.72 ? 128 ARG B CD  1 
ATOM   2914 N  NE  . ARG B 1 128 ? 113.191 109.623 108.897 1.00 130.76 ? 128 ARG B NE  1 
ATOM   2915 C  CZ  . ARG B 1 128 ? 112.641 110.330 109.874 1.00 130.24 ? 128 ARG B CZ  1 
ATOM   2916 N  NH1 . ARG B 1 128 ? 113.239 110.474 111.044 1.00 125.52 ? 128 ARG B NH1 1 
ATOM   2917 N  NH2 . ARG B 1 128 ? 111.459 110.904 109.672 1.00 129.62 ? 128 ARG B NH2 1 
ATOM   2918 N  N   . PRO B 1 129 ? 115.047 108.342 103.290 1.00 114.89 ? 129 PRO B N   1 
ATOM   2919 C  CA  . PRO B 1 129 ? 115.209 109.090 102.042 1.00 116.74 ? 129 PRO B CA  1 
ATOM   2920 C  C   . PRO B 1 129 ? 114.995 110.577 102.262 1.00 119.73 ? 129 PRO B C   1 
ATOM   2921 O  O   . PRO B 1 129 ? 114.301 110.999 103.189 1.00 119.85 ? 129 PRO B O   1 
ATOM   2922 C  CB  . PRO B 1 129 ? 114.127 108.500 101.133 1.00 118.43 ? 129 PRO B CB  1 
ATOM   2923 C  CG  . PRO B 1 129 ? 113.100 107.975 102.071 1.00 116.36 ? 129 PRO B CG  1 
ATOM   2924 C  CD  . PRO B 1 129 ? 113.846 107.491 103.276 1.00 114.52 ? 129 PRO B CD  1 
ATOM   2925 N  N   . ALA B 1 130 ? 115.619 111.374 101.399 1.00 112.71 ? 130 ALA B N   1 
ATOM   2926 C  CA  . ALA B 1 130 ? 115.439 112.817 101.456 1.00 107.08 ? 130 ALA B CA  1 
ATOM   2927 C  C   . ALA B 1 130 ? 113.987 113.176 101.176 1.00 110.96 ? 130 ALA B C   1 
ATOM   2928 O  O   . ALA B 1 130 ? 113.370 112.645 100.249 1.00 112.03 ? 130 ALA B O   1 
ATOM   2929 C  CB  . ALA B 1 130 ? 116.359 113.502 100.449 1.00 102.19 ? 130 ALA B CB  1 
ATOM   2930 N  N   . THR B 1 131 ? 113.439 114.075 101.985 1.00 117.14 ? 131 THR B N   1 
ATOM   2931 C  CA  . THR B 1 131 ? 112.060 114.506 101.850 1.00 114.83 ? 131 THR B CA  1 
ATOM   2932 C  C   . THR B 1 131 ? 112.000 115.844 101.120 1.00 114.92 ? 131 THR B C   1 
ATOM   2933 O  O   . THR B 1 131 ? 113.015 116.403 100.702 1.00 115.40 ? 131 THR B O   1 
ATOM   2934 C  CB  . THR B 1 131 ? 111.392 114.598 103.222 1.00 115.62 ? 131 THR B CB  1 
ATOM   2935 O  OG1 . THR B 1 131 ? 111.852 115.772 103.899 1.00 119.56 ? 131 THR B OG1 1 
ATOM   2936 C  CG2 . THR B 1 131 ? 111.733 113.382 104.056 1.00 119.68 ? 131 THR B CG2 1 
ATOM   2937 N  N   . ARG B 1 132 ? 110.783 116.360 100.958 1.00 119.34 ? 132 ARG B N   1 
ATOM   2938 C  CA  . ARG B 1 132 ? 110.599 117.651 100.314 1.00 116.13 ? 132 ARG B CA  1 
ATOM   2939 C  C   . ARG B 1 132 ? 110.941 118.814 101.231 1.00 119.06 ? 132 ARG B C   1 
ATOM   2940 O  O   . ARG B 1 132 ? 111.093 119.940 100.750 1.00 125.31 ? 132 ARG B O   1 
ATOM   2941 C  CB  . ARG B 1 132 ? 109.163 117.789 99.814  1.00 115.52 ? 132 ARG B CB  1 
ATOM   2942 C  CG  . ARG B 1 132 ? 108.840 116.870 98.659  1.00 121.72 ? 132 ARG B CG  1 
ATOM   2943 C  CD  . ARG B 1 132 ? 107.351 116.635 98.537  1.00 124.56 ? 132 ARG B CD  1 
ATOM   2944 N  NE  . ARG B 1 132 ? 106.832 117.118 97.265  1.00 127.59 ? 132 ARG B NE  1 
ATOM   2945 C  CZ  . ARG B 1 132 ? 106.728 116.378 96.170  1.00 131.06 ? 132 ARG B CZ  1 
ATOM   2946 N  NH1 . ARG B 1 132 ? 107.102 115.110 96.156  1.00 131.61 ? 132 ARG B NH1 1 
ATOM   2947 N  NH2 . ARG B 1 132 ? 106.238 116.924 95.062  1.00 128.36 ? 132 ARG B NH2 1 
ATOM   2948 N  N   . THR B 1 133 ? 111.057 118.572 102.535 1.00 108.75 ? 133 THR B N   1 
ATOM   2949 C  CA  . THR B 1 133 ? 111.495 119.597 103.468 1.00 109.40 ? 133 THR B CA  1 
ATOM   2950 C  C   . THR B 1 133 ? 112.953 119.448 103.869 1.00 108.54 ? 133 THR B C   1 
ATOM   2951 O  O   . THR B 1 133 ? 113.526 120.390 104.424 1.00 110.01 ? 133 THR B O   1 
ATOM   2952 C  CB  . THR B 1 133 ? 110.627 119.578 104.730 1.00 111.13 ? 133 THR B CB  1 
ATOM   2953 O  OG1 . THR B 1 133 ? 110.708 118.288 105.346 1.00 116.04 ? 133 THR B OG1 1 
ATOM   2954 C  CG2 . THR B 1 133 ? 109.182 119.869 104.379 1.00 110.81 ? 133 THR B CG2 1 
ATOM   2955 N  N   . MET B 1 134 ? 113.560 118.292 103.608 1.00 107.68 ? 134 MET B N   1 
ATOM   2956 C  CA  . MET B 1 134 ? 114.973 118.042 103.882 1.00 101.26 ? 134 MET B CA  1 
ATOM   2957 C  C   . MET B 1 134 ? 115.557 117.485 102.590 1.00 106.15 ? 134 MET B C   1 
ATOM   2958 O  O   . MET B 1 134 ? 115.640 116.268 102.412 1.00 112.96 ? 134 MET B O   1 
ATOM   2959 C  CB  . MET B 1 134 ? 115.148 117.080 105.048 1.00 99.40  ? 134 MET B CB  1 
ATOM   2960 C  CG  . MET B 1 134 ? 114.432 117.512 106.315 1.00 110.70 ? 134 MET B CG  1 
ATOM   2961 S  SD  . MET B 1 134 ? 115.370 118.684 107.302 1.00 124.95 ? 134 MET B SD  1 
ATOM   2962 C  CE  . MET B 1 134 ? 117.009 118.009 107.116 1.00 114.34 ? 134 MET B CE  1 
ATOM   2963 N  N   . THR B 1 135 ? 115.960 118.381 101.689 1.00 102.85 ? 135 THR B N   1 
ATOM   2964 C  CA  . THR B 1 135 ? 116.381 117.957 100.358 1.00 98.29  ? 135 THR B CA  1 
ATOM   2965 C  C   . THR B 1 135 ? 117.720 117.237 100.384 1.00 97.23  ? 135 THR B C   1 
ATOM   2966 O  O   . THR B 1 135 ? 117.937 116.310 99.597  1.00 97.52  ? 135 THR B O   1 
ATOM   2967 C  CB  . THR B 1 135 ? 116.449 119.162 99.426  1.00 97.42  ? 135 THR B CB  1 
ATOM   2968 O  OG1 . THR B 1 135 ? 117.029 120.269 100.124 1.00 104.77 ? 135 THR B OG1 1 
ATOM   2969 C  CG2 . THR B 1 135 ? 115.061 119.546 98.961  1.00 96.74  ? 135 THR B CG2 1 
ATOM   2970 N  N   . PHE B 1 136 ? 118.628 117.646 101.265 1.00 97.79  ? 136 PHE B N   1 
ATOM   2971 C  CA  . PHE B 1 136 ? 119.951 117.042 101.326 1.00 93.08  ? 136 PHE B CA  1 
ATOM   2972 C  C   . PHE B 1 136 ? 119.973 115.727 102.089 1.00 100.19 ? 136 PHE B C   1 
ATOM   2973 O  O   . PHE B 1 136 ? 120.954 114.985 101.979 1.00 110.34 ? 136 PHE B O   1 
ATOM   2974 C  CB  . PHE B 1 136 ? 120.937 118.013 101.973 1.00 92.04  ? 136 PHE B CB  1 
ATOM   2975 C  CG  . PHE B 1 136 ? 121.485 119.036 101.029 1.00 98.39  ? 136 PHE B CG  1 
ATOM   2976 C  CD1 . PHE B 1 136 ? 122.494 118.710 100.145 1.00 97.66  ? 136 PHE B CD1 1 
ATOM   2977 C  CD2 . PHE B 1 136 ? 120.995 120.327 101.029 1.00 101.78 ? 136 PHE B CD2 1 
ATOM   2978 C  CE1 . PHE B 1 136 ? 123.000 119.651 99.279  1.00 97.43  ? 136 PHE B CE1 1 
ATOM   2979 C  CE2 . PHE B 1 136 ? 121.498 121.269 100.166 1.00 101.35 ? 136 PHE B CE2 1 
ATOM   2980 C  CZ  . PHE B 1 136 ? 122.502 120.932 99.291  1.00 94.96  ? 136 PHE B CZ  1 
ATOM   2981 N  N   . GLY B 1 137 ? 118.930 115.419 102.850 1.00 100.51 ? 137 GLY B N   1 
ATOM   2982 C  CA  . GLY B 1 137 ? 118.929 114.231 103.677 1.00 96.81  ? 137 GLY B CA  1 
ATOM   2983 C  C   . GLY B 1 137 ? 118.998 114.578 105.148 1.00 101.99 ? 137 GLY B C   1 
ATOM   2984 O  O   . GLY B 1 137 ? 118.518 115.636 105.559 1.00 112.13 ? 137 GLY B O   1 
ATOM   2985 N  N   . TRP B 1 138 ? 119.603 113.706 105.951 1.00 98.52  ? 138 TRP B N   1 
ATOM   2986 C  CA  . TRP B 1 138 ? 119.697 113.920 107.390 1.00 100.41 ? 138 TRP B CA  1 
ATOM   2987 C  C   . TRP B 1 138 ? 121.137 113.813 107.872 1.00 103.48 ? 138 TRP B C   1 
ATOM   2988 O  O   . TRP B 1 138 ? 121.386 113.448 109.023 1.00 111.69 ? 138 TRP B O   1 
ATOM   2989 C  CB  . TRP B 1 138 ? 118.806 112.937 108.144 1.00 106.81 ? 138 TRP B CB  1 
ATOM   2990 C  CG  . TRP B 1 138 ? 117.383 112.963 107.699 1.00 104.67 ? 138 TRP B CG  1 
ATOM   2991 C  CD1 . TRP B 1 138 ? 116.854 112.337 106.612 1.00 103.30 ? 138 TRP B CD1 1 
ATOM   2992 C  CD2 . TRP B 1 138 ? 116.303 113.653 108.331 1.00 100.28 ? 138 TRP B CD2 1 
ATOM   2993 N  NE1 . TRP B 1 138 ? 115.510 112.595 106.526 1.00 99.53  ? 138 TRP B NE1 1 
ATOM   2994 C  CE2 . TRP B 1 138 ? 115.147 113.401 107.571 1.00 101.71 ? 138 TRP B CE2 1 
ATOM   2995 C  CE3 . TRP B 1 138 ? 116.200 114.459 109.466 1.00 99.34  ? 138 TRP B CE3 1 
ATOM   2996 C  CZ2 . TRP B 1 138 ? 113.906 113.925 107.908 1.00 106.49 ? 138 TRP B CZ2 1 
ATOM   2997 C  CZ3 . TRP B 1 138 ? 114.969 114.978 109.799 1.00 104.55 ? 138 TRP B CZ3 1 
ATOM   2998 C  CH2 . TRP B 1 138 ? 113.838 114.710 109.024 1.00 108.48 ? 138 TRP B CH2 1 
ATOM   2999 N  N   . HIS B 1 139 ? 122.097 114.137 107.007 1.00 94.06  ? 139 HIS B N   1 
ATOM   3000 C  CA  . HIS B 1 139 ? 123.502 113.985 107.360 1.00 95.52  ? 139 HIS B CA  1 
ATOM   3001 C  C   . HIS B 1 139 ? 123.969 115.020 108.372 1.00 104.81 ? 139 HIS B C   1 
ATOM   3002 O  O   . HIS B 1 139 ? 124.933 114.765 109.099 1.00 111.34 ? 139 HIS B O   1 
ATOM   3003 C  CB  . HIS B 1 139 ? 124.359 114.057 106.102 1.00 94.57  ? 139 HIS B CB  1 
ATOM   3004 C  CG  . HIS B 1 139 ? 123.910 113.129 105.020 1.00 100.02 ? 139 HIS B CG  1 
ATOM   3005 N  ND1 . HIS B 1 139 ? 123.107 113.536 103.978 1.00 101.77 ? 139 HIS B ND1 1 
ATOM   3006 C  CD2 . HIS B 1 139 ? 124.146 111.812 104.821 1.00 104.76 ? 139 HIS B CD2 1 
ATOM   3007 C  CE1 . HIS B 1 139 ? 122.869 112.510 103.181 1.00 109.11 ? 139 HIS B CE1 1 
ATOM   3008 N  NE2 . HIS B 1 139 ? 123.489 111.451 103.670 1.00 111.15 ? 139 HIS B NE2 1 
ATOM   3009 N  N   . ARG B 1 140 ? 123.312 116.177 108.439 1.00 99.24  ? 140 ARG B N   1 
ATOM   3010 C  CA  . ARG B 1 140 ? 123.680 117.204 109.405 1.00 88.33  ? 140 ARG B CA  1 
ATOM   3011 C  C   . ARG B 1 140 ? 123.380 116.790 110.839 1.00 94.83  ? 140 ARG B C   1 
ATOM   3012 O  O   . ARG B 1 140 ? 123.837 117.462 111.774 1.00 102.44 ? 140 ARG B O   1 
ATOM   3013 C  CB  . ARG B 1 140 ? 122.953 118.504 109.065 1.00 93.26  ? 140 ARG B CB  1 
ATOM   3014 C  CG  . ARG B 1 140 ? 123.645 119.761 109.546 1.00 103.21 ? 140 ARG B CG  1 
ATOM   3015 C  CD  . ARG B 1 140 ? 125.077 119.836 109.071 1.00 100.11 ? 140 ARG B CD  1 
ATOM   3016 N  NE  . ARG B 1 140 ? 125.199 120.436 107.749 1.00 99.30  ? 140 ARG B NE  1 
ATOM   3017 C  CZ  . ARG B 1 140 ? 125.331 121.736 107.528 1.00 96.97  ? 140 ARG B CZ  1 
ATOM   3018 N  NH1 . ARG B 1 140 ? 125.321 122.610 108.518 1.00 103.86 ? 140 ARG B NH1 1 
ATOM   3019 N  NH2 . ARG B 1 140 ? 125.477 122.170 106.281 1.00 99.17  ? 140 ARG B NH2 1 
ATOM   3020 N  N   . SER B 1 141 ? 122.627 115.705 111.031 1.00 105.21 ? 141 SER B N   1 
ATOM   3021 C  CA  . SER B 1 141 ? 122.325 115.235 112.376 1.00 103.98 ? 141 SER B CA  1 
ATOM   3022 C  C   . SER B 1 141 ? 123.583 114.816 113.117 1.00 103.44 ? 141 SER B C   1 
ATOM   3023 O  O   . SER B 1 141 ? 123.662 114.977 114.336 1.00 106.45 ? 141 SER B O   1 
ATOM   3024 C  CB  . SER B 1 141 ? 121.337 114.073 112.314 1.00 101.52 ? 141 SER B CB  1 
ATOM   3025 O  OG  . SER B 1 141 ? 121.865 113.002 111.555 1.00 108.25 ? 141 SER B OG  1 
ATOM   3026 N  N   . GLU B 1 142 ? 124.574 114.278 112.406 1.00 109.74 ? 142 GLU B N   1 
ATOM   3027 C  CA  . GLU B 1 142 ? 125.825 113.892 113.050 1.00 109.89 ? 142 GLU B CA  1 
ATOM   3028 C  C   . GLU B 1 142 ? 126.544 115.107 113.626 1.00 110.09 ? 142 GLU B C   1 
ATOM   3029 O  O   . GLU B 1 142 ? 127.000 115.092 114.777 1.00 111.85 ? 142 GLU B O   1 
ATOM   3030 C  CB  . GLU B 1 142 ? 126.709 113.155 112.046 1.00 109.71 ? 142 GLU B CB  1 
ATOM   3031 C  CG  . GLU B 1 142 ? 128.193 113.266 112.308 1.00 120.01 ? 142 GLU B CG  1 
ATOM   3032 C  CD  . GLU B 1 142 ? 129.014 112.564 111.247 1.00 126.20 ? 142 GLU B CD  1 
ATOM   3033 O  OE1 . GLU B 1 142 ? 128.457 111.696 110.544 1.00 120.19 ? 142 GLU B OE1 1 
ATOM   3034 O  OE2 . GLU B 1 142 ? 130.214 112.880 111.114 1.00 125.63 ? 142 GLU B OE2 1 
ATOM   3035 N  N   . THR B 1 143 ? 126.642 116.179 112.838 1.00 107.67 ? 143 THR B N   1 
ATOM   3036 C  CA  . THR B 1 143 ? 127.267 117.404 113.323 1.00 102.92 ? 143 THR B CA  1 
ATOM   3037 C  C   . THR B 1 143 ? 126.479 118.003 114.479 1.00 105.46 ? 143 THR B C   1 
ATOM   3038 O  O   . THR B 1 143 ? 127.063 118.478 115.462 1.00 114.13 ? 143 THR B O   1 
ATOM   3039 C  CB  . THR B 1 143 ? 127.392 118.412 112.185 1.00 103.77 ? 143 THR B CB  1 
ATOM   3040 O  OG1 . THR B 1 143 ? 127.820 117.738 110.997 1.00 112.69 ? 143 THR B OG1 1 
ATOM   3041 C  CG2 . THR B 1 143 ? 128.398 119.488 112.537 1.00 108.46 ? 143 THR B CG2 1 
ATOM   3042 N  N   . LEU B 1 144 ? 125.150 117.993 114.379 1.00 109.89 ? 144 LEU B N   1 
ATOM   3043 C  CA  . LEU B 1 144 ? 124.336 118.541 115.459 1.00 111.37 ? 144 LEU B CA  1 
ATOM   3044 C  C   . LEU B 1 144 ? 124.502 117.732 116.740 1.00 111.90 ? 144 LEU B C   1 
ATOM   3045 O  O   . LEU B 1 144 ? 124.554 118.299 117.837 1.00 114.33 ? 144 LEU B O   1 
ATOM   3046 C  CB  . LEU B 1 144 ? 122.872 118.598 115.033 1.00 110.63 ? 144 LEU B CB  1 
ATOM   3047 C  CG  . LEU B 1 144 ? 122.514 119.727 114.064 1.00 109.57 ? 144 LEU B CG  1 
ATOM   3048 C  CD1 . LEU B 1 144 ? 121.073 120.147 114.251 1.00 114.12 ? 144 LEU B CD1 1 
ATOM   3049 C  CD2 . LEU B 1 144 ? 123.436 120.916 114.246 1.00 108.03 ? 144 LEU B CD2 1 
ATOM   3050 N  N   . GLY B 1 145 ? 124.598 116.408 116.622 1.00 103.32 ? 145 GLY B N   1 
ATOM   3051 C  CA  . GLY B 1 145 ? 124.828 115.584 117.797 1.00 101.52 ? 145 GLY B CA  1 
ATOM   3052 C  C   . GLY B 1 145 ? 126.191 115.819 118.417 1.00 107.31 ? 145 GLY B C   1 
ATOM   3053 O  O   . GLY B 1 145 ? 126.330 115.834 119.643 1.00 111.81 ? 145 GLY B O   1 
ATOM   3054 N  N   . ALA B 1 146 ? 127.217 116.001 117.582 1.00 108.04 ? 146 ALA B N   1 
ATOM   3055 C  CA  . ALA B 1 146 ? 128.536 116.333 118.113 1.00 108.13 ? 146 ALA B CA  1 
ATOM   3056 C  C   . ALA B 1 146 ? 128.507 117.657 118.865 1.00 107.30 ? 146 ALA B C   1 
ATOM   3057 O  O   . ALA B 1 146 ? 129.078 117.778 119.958 1.00 108.66 ? 146 ALA B O   1 
ATOM   3058 C  CB  . ALA B 1 146 ? 129.561 116.380 116.982 1.00 102.27 ? 146 ALA B CB  1 
ATOM   3059 N  N   . LEU B 1 147 ? 127.831 118.659 118.300 1.00 97.41  ? 147 LEU B N   1 
ATOM   3060 C  CA  . LEU B 1 147 ? 127.710 119.944 118.981 1.00 94.73  ? 147 LEU B CA  1 
ATOM   3061 C  C   . LEU B 1 147 ? 126.959 119.801 120.297 1.00 99.70  ? 147 LEU B C   1 
ATOM   3062 O  O   . LEU B 1 147 ? 127.331 120.416 121.303 1.00 107.68 ? 147 LEU B O   1 
ATOM   3063 C  CB  . LEU B 1 147 ? 127.011 120.953 118.074 1.00 98.38  ? 147 LEU B CB  1 
ATOM   3064 C  CG  . LEU B 1 147 ? 126.793 122.342 118.671 1.00 101.52 ? 147 LEU B CG  1 
ATOM   3065 C  CD1 . LEU B 1 147 ? 128.107 123.088 118.768 1.00 100.30 ? 147 LEU B CD1 1 
ATOM   3066 C  CD2 . LEU B 1 147 ? 125.792 123.124 117.845 1.00 102.20 ? 147 LEU B CD2 1 
ATOM   3067 N  N   . ALA B 1 148 ? 125.893 118.998 120.307 1.00 97.92  ? 148 ALA B N   1 
ATOM   3068 C  CA  . ALA B 1 148 ? 125.134 118.788 121.535 1.00 102.15 ? 148 ALA B CA  1 
ATOM   3069 C  C   . ALA B 1 148 ? 125.988 118.122 122.604 1.00 105.34 ? 148 ALA B C   1 
ATOM   3070 O  O   . ALA B 1 148 ? 125.924 118.493 123.782 1.00 111.48 ? 148 ALA B O   1 
ATOM   3071 C  CB  . ALA B 1 148 ? 123.890 117.951 121.244 1.00 100.39 ? 148 ALA B CB  1 
ATOM   3072 N  N   . SER B 1 149 ? 126.789 117.129 122.213 1.00 103.15 ? 149 SER B N   1 
ATOM   3073 C  CA  . SER B 1 149 ? 127.669 116.474 123.175 1.00 106.27 ? 149 SER B CA  1 
ATOM   3074 C  C   . SER B 1 149 ? 128.689 117.453 123.740 1.00 111.60 ? 149 SER B C   1 
ATOM   3075 O  O   . SER B 1 149 ? 128.955 117.457 124.949 1.00 116.28 ? 149 SER B O   1 
ATOM   3076 C  CB  . SER B 1 149 ? 128.368 115.285 122.522 1.00 106.08 ? 149 SER B CB  1 
ATOM   3077 O  OG  . SER B 1 149 ? 129.456 115.715 121.726 1.00 115.02 ? 149 SER B OG  1 
ATOM   3078 N  N   . VAL B 1 150 ? 129.264 118.299 122.882 1.00 112.67 ? 150 VAL B N   1 
ATOM   3079 C  CA  . VAL B 1 150 ? 130.228 119.289 123.358 1.00 108.24 ? 150 VAL B CA  1 
ATOM   3080 C  C   . VAL B 1 150 ? 129.568 120.252 124.338 1.00 108.74 ? 150 VAL B C   1 
ATOM   3081 O  O   . VAL B 1 150 ? 130.137 120.585 125.387 1.00 116.41 ? 150 VAL B O   1 
ATOM   3082 C  CB  . VAL B 1 150 ? 130.858 120.034 122.166 1.00 106.47 ? 150 VAL B CB  1 
ATOM   3083 C  CG1 . VAL B 1 150 ? 131.397 121.384 122.602 1.00 107.38 ? 150 VAL B CG1 1 
ATOM   3084 C  CG2 . VAL B 1 150 ? 131.957 119.196 121.543 1.00 103.63 ? 150 VAL B CG2 1 
ATOM   3085 N  N   . VAL B 1 151 ? 128.357 120.709 124.019 1.00 106.31 ? 151 VAL B N   1 
ATOM   3086 C  CA  . VAL B 1 151 ? 127.662 121.654 124.888 1.00 108.26 ? 151 VAL B CA  1 
ATOM   3087 C  C   . VAL B 1 151 ? 127.344 121.015 126.234 1.00 113.68 ? 151 VAL B C   1 
ATOM   3088 O  O   . VAL B 1 151 ? 127.499 121.644 127.288 1.00 120.26 ? 151 VAL B O   1 
ATOM   3089 C  CB  . VAL B 1 151 ? 126.393 122.181 124.193 1.00 114.34 ? 151 VAL B CB  1 
ATOM   3090 C  CG1 . VAL B 1 151 ? 125.471 122.848 125.195 1.00 114.53 ? 151 VAL B CG1 1 
ATOM   3091 C  CG2 . VAL B 1 151 ? 126.768 123.149 123.090 1.00 114.01 ? 151 VAL B CG2 1 
ATOM   3092 N  N   . SER B 1 152 ? 126.886 119.761 126.224 1.00 109.17 ? 152 SER B N   1 
ATOM   3093 C  CA  . SER B 1 152 ? 126.589 119.076 127.479 1.00 108.84 ? 152 SER B CA  1 
ATOM   3094 C  C   . SER B 1 152 ? 127.846 118.898 128.320 1.00 110.83 ? 152 SER B C   1 
ATOM   3095 O  O   . SER B 1 152 ? 127.813 119.058 129.550 1.00 118.61 ? 152 SER B O   1 
ATOM   3096 C  CB  . SER B 1 152 ? 125.938 117.725 127.195 1.00 110.46 ? 152 SER B CB  1 
ATOM   3097 O  OG  . SER B 1 152 ? 126.918 116.742 126.925 1.00 113.23 ? 152 SER B OG  1 
ATOM   3098 N  N   . LEU B 1 153 ? 128.963 118.555 127.676 1.00 111.10 ? 153 LEU B N   1 
ATOM   3099 C  CA  . LEU B 1 153 ? 130.221 118.444 128.403 1.00 113.85 ? 153 LEU B CA  1 
ATOM   3100 C  C   . LEU B 1 153 ? 130.603 119.773 129.034 1.00 116.74 ? 153 LEU B C   1 
ATOM   3101 O  O   . LEU B 1 153 ? 131.044 119.816 130.187 1.00 115.61 ? 153 LEU B O   1 
ATOM   3102 C  CB  . LEU B 1 153 ? 131.327 117.957 127.470 1.00 116.89 ? 153 LEU B CB  1 
ATOM   3103 C  CG  . LEU B 1 153 ? 132.748 118.049 128.025 1.00 116.54 ? 153 LEU B CG  1 
ATOM   3104 C  CD1 . LEU B 1 153 ? 132.924 117.100 129.194 1.00 115.05 ? 153 LEU B CD1 1 
ATOM   3105 C  CD2 . LEU B 1 153 ? 133.760 117.754 126.939 1.00 114.92 ? 153 LEU B CD2 1 
ATOM   3106 N  N   . TRP B 1 154 ? 130.435 120.872 128.293 1.00 126.53 ? 154 TRP B N   1 
ATOM   3107 C  CA  . TRP B 1 154 ? 130.729 122.188 128.853 1.00 121.25 ? 154 TRP B CA  1 
ATOM   3108 C  C   . TRP B 1 154 ? 129.834 122.490 130.047 1.00 122.16 ? 154 TRP B C   1 
ATOM   3109 O  O   . TRP B 1 154 ? 130.297 123.034 131.054 1.00 125.38 ? 154 TRP B O   1 
ATOM   3110 C  CB  . TRP B 1 154 ? 130.568 123.267 127.784 1.00 117.87 ? 154 TRP B CB  1 
ATOM   3111 C  CG  . TRP B 1 154 ? 131.810 123.526 126.997 1.00 118.94 ? 154 TRP B CG  1 
ATOM   3112 C  CD1 . TRP B 1 154 ? 132.316 122.756 125.997 1.00 122.50 ? 154 TRP B CD1 1 
ATOM   3113 C  CD2 . TRP B 1 154 ? 132.706 124.632 127.145 1.00 132.77 ? 154 TRP B CD2 1 
ATOM   3114 N  NE1 . TRP B 1 154 ? 133.470 123.314 125.507 1.00 124.44 ? 154 TRP B NE1 1 
ATOM   3115 C  CE2 . TRP B 1 154 ? 133.733 124.466 126.197 1.00 131.49 ? 154 TRP B CE2 1 
ATOM   3116 C  CE3 . TRP B 1 154 ? 132.741 125.748 127.988 1.00 133.41 ? 154 TRP B CE3 1 
ATOM   3117 C  CZ2 . TRP B 1 154 ? 134.783 125.372 126.067 1.00 128.07 ? 154 TRP B CZ2 1 
ATOM   3118 C  CZ3 . TRP B 1 154 ? 133.785 126.646 127.858 1.00 125.27 ? 154 TRP B CZ3 1 
ATOM   3119 C  CH2 . TRP B 1 154 ? 134.791 126.453 126.905 1.00 124.88 ? 154 TRP B CH2 1 
ATOM   3120 N  N   . MET B 1 155 ? 128.550 122.141 129.953 1.00 125.38 ? 155 MET B N   1 
ATOM   3121 C  CA  . MET B 1 155 ? 127.626 122.369 131.062 1.00 121.64 ? 155 MET B CA  1 
ATOM   3122 C  C   . MET B 1 155 ? 128.086 121.645 132.320 1.00 125.04 ? 155 MET B C   1 
ATOM   3123 O  O   . MET B 1 155 ? 128.216 122.249 133.396 1.00 130.62 ? 155 MET B O   1 
ATOM   3124 C  CB  . MET B 1 155 ? 126.226 121.892 130.677 1.00 123.80 ? 155 MET B CB  1 
ATOM   3125 C  CG  . MET B 1 155 ? 125.523 122.717 129.627 1.00 131.55 ? 155 MET B CG  1 
ATOM   3126 S  SD  . MET B 1 155 ? 123.754 122.819 129.960 1.00 149.90 ? 155 MET B SD  1 
ATOM   3127 C  CE  . MET B 1 155 ? 123.089 122.799 128.298 1.00 128.40 ? 155 MET B CE  1 
ATOM   3128 N  N   . VAL B 1 156 ? 128.336 120.340 132.200 1.00 114.64 ? 156 VAL B N   1 
ATOM   3129 C  CA  . VAL B 1 156 ? 128.701 119.554 133.374 1.00 114.05 ? 156 VAL B CA  1 
ATOM   3130 C  C   . VAL B 1 156 ? 130.048 120.005 133.922 1.00 118.06 ? 156 VAL B C   1 
ATOM   3131 O  O   . VAL B 1 156 ? 130.244 120.081 135.142 1.00 117.84 ? 156 VAL B O   1 
ATOM   3132 C  CB  . VAL B 1 156 ? 128.692 118.053 133.040 1.00 113.48 ? 156 VAL B CB  1 
ATOM   3133 C  CG1 . VAL B 1 156 ? 128.911 117.239 134.295 1.00 114.99 ? 156 VAL B CG1 1 
ATOM   3134 C  CG2 . VAL B 1 156 ? 127.378 117.670 132.393 1.00 114.82 ? 156 VAL B CG2 1 
ATOM   3135 N  N   . THR B 1 157 ? 130.997 120.316 133.036 1.00 120.44 ? 157 THR B N   1 
ATOM   3136 C  CA  . THR B 1 157 ? 132.303 120.780 133.483 1.00 118.59 ? 157 THR B CA  1 
ATOM   3137 C  C   . THR B 1 157 ? 132.193 122.104 134.223 1.00 121.64 ? 157 THR B C   1 
ATOM   3138 O  O   . THR B 1 157 ? 132.866 122.311 135.236 1.00 125.40 ? 157 THR B O   1 
ATOM   3139 C  CB  . THR B 1 157 ? 133.246 120.903 132.288 1.00 123.43 ? 157 THR B CB  1 
ATOM   3140 O  OG1 . THR B 1 157 ? 133.609 119.594 131.834 1.00 125.39 ? 157 THR B OG1 1 
ATOM   3141 C  CG2 . THR B 1 157 ? 134.502 121.660 132.670 1.00 124.14 ? 157 THR B CG2 1 
ATOM   3142 N  N   . GLY B 1 158 ? 131.349 123.015 133.738 1.00 121.00 ? 158 GLY B N   1 
ATOM   3143 C  CA  . GLY B 1 158 ? 131.160 124.274 134.438 1.00 116.30 ? 158 GLY B CA  1 
ATOM   3144 C  C   . GLY B 1 158 ? 130.540 124.087 135.808 1.00 113.81 ? 158 GLY B C   1 
ATOM   3145 O  O   . GLY B 1 158 ? 130.947 124.733 136.778 1.00 117.39 ? 158 GLY B O   1 
ATOM   3146 N  N   . ILE B 1 159 ? 129.550 123.198 135.909 1.00 107.71 ? 159 ILE B N   1 
ATOM   3147 C  CA  . ILE B 1 159 ? 128.941 122.927 137.210 1.00 106.16 ? 159 ILE B CA  1 
ATOM   3148 C  C   . ILE B 1 159 ? 129.983 122.369 138.174 1.00 112.52 ? 159 ILE B C   1 
ATOM   3149 O  O   . ILE B 1 159 ? 130.083 122.798 139.332 1.00 119.94 ? 159 ILE B O   1 
ATOM   3150 C  CB  . ILE B 1 159 ? 127.743 121.973 137.054 1.00 108.94 ? 159 ILE B CB  1 
ATOM   3151 C  CG1 . ILE B 1 159 ? 126.464 122.766 136.796 1.00 113.07 ? 159 ILE B CG1 1 
ATOM   3152 C  CG2 . ILE B 1 159 ? 127.570 121.118 138.294 1.00 108.06 ? 159 ILE B CG2 1 
ATOM   3153 C  CD1 . ILE B 1 159 ? 125.369 121.951 136.154 1.00 112.70 ? 159 ILE B CD1 1 
ATOM   3154 N  N   . LEU B 1 160 ? 130.790 121.416 137.700 1.00 118.85 ? 160 LEU B N   1 
ATOM   3155 C  CA  . LEU B 1 160 ? 131.816 120.825 138.552 1.00 116.05 ? 160 LEU B CA  1 
ATOM   3156 C  C   . LEU B 1 160 ? 132.866 121.851 138.953 1.00 115.59 ? 160 LEU B C   1 
ATOM   3157 O  O   . LEU B 1 160 ? 133.345 121.846 140.092 1.00 117.10 ? 160 LEU B O   1 
ATOM   3158 C  CB  . LEU B 1 160 ? 132.471 119.644 137.840 1.00 114.28 ? 160 LEU B CB  1 
ATOM   3159 C  CG  . LEU B 1 160 ? 131.609 118.390 137.734 1.00 112.78 ? 160 LEU B CG  1 
ATOM   3160 C  CD1 . LEU B 1 160 ? 132.356 117.296 136.999 1.00 116.79 ? 160 LEU B CD1 1 
ATOM   3161 C  CD2 . LEU B 1 160 ? 131.188 117.927 139.112 1.00 112.61 ? 160 LEU B CD2 1 
ATOM   3162 N  N   . LEU B 1 161 ? 133.250 122.730 138.027 1.00 114.81 ? 161 LEU B N   1 
ATOM   3163 C  CA  . LEU B 1 161 ? 134.237 123.755 138.338 1.00 112.91 ? 161 LEU B CA  1 
ATOM   3164 C  C   . LEU B 1 161 ? 133.711 124.725 139.382 1.00 118.71 ? 161 LEU B C   1 
ATOM   3165 O  O   . LEU B 1 161 ? 134.445 125.125 140.293 1.00 124.28 ? 161 LEU B O   1 
ATOM   3166 C  CB  . LEU B 1 161 ? 134.636 124.500 137.067 1.00 112.75 ? 161 LEU B CB  1 
ATOM   3167 C  CG  . LEU B 1 161 ? 135.777 123.874 136.271 1.00 116.73 ? 161 LEU B CG  1 
ATOM   3168 C  CD1 . LEU B 1 161 ? 136.142 124.746 135.088 1.00 120.85 ? 161 LEU B CD1 1 
ATOM   3169 C  CD2 . LEU B 1 161 ? 136.978 123.655 137.167 1.00 119.37 ? 161 LEU B CD2 1 
ATOM   3170 N  N   . TYR B 1 162 ? 132.441 125.121 139.268 1.00 120.03 ? 162 TYR B N   1 
ATOM   3171 C  CA  . TYR B 1 162 ? 131.863 125.987 140.288 1.00 121.25 ? 162 TYR B CA  1 
ATOM   3172 C  C   . TYR B 1 162 ? 131.836 125.292 141.641 1.00 123.74 ? 162 TYR B C   1 
ATOM   3173 O  O   . TYR B 1 162 ? 132.148 125.907 142.669 1.00 131.63 ? 162 TYR B O   1 
ATOM   3174 C  CB  . TYR B 1 162 ? 130.455 126.423 139.889 1.00 120.26 ? 162 TYR B CB  1 
ATOM   3175 C  CG  . TYR B 1 162 ? 129.647 126.937 141.058 1.00 123.67 ? 162 TYR B CG  1 
ATOM   3176 C  CD1 . TYR B 1 162 ? 129.797 128.241 141.506 1.00 122.40 ? 162 TYR B CD1 1 
ATOM   3177 C  CD2 . TYR B 1 162 ? 128.734 126.121 141.713 1.00 122.06 ? 162 TYR B CD2 1 
ATOM   3178 C  CE1 . TYR B 1 162 ? 129.068 128.716 142.574 1.00 123.80 ? 162 TYR B CE1 1 
ATOM   3179 C  CE2 . TYR B 1 162 ? 128.001 126.589 142.783 1.00 125.96 ? 162 TYR B CE2 1 
ATOM   3180 C  CZ  . TYR B 1 162 ? 128.171 127.887 143.208 1.00 127.55 ? 162 TYR B CZ  1 
ATOM   3181 O  OH  . TYR B 1 162 ? 127.440 128.358 144.272 1.00 125.82 ? 162 TYR B OH  1 
ATOM   3182 N  N   . LEU B 1 163 ? 131.460 124.012 141.664 1.00 112.79 ? 163 LEU B N   1 
ATOM   3183 C  CA  . LEU B 1 163 ? 131.437 123.284 142.929 1.00 112.49 ? 163 LEU B CA  1 
ATOM   3184 C  C   . LEU B 1 163 ? 132.828 123.201 143.543 1.00 117.99 ? 163 LEU B C   1 
ATOM   3185 O  O   . LEU B 1 163 ? 132.993 123.387 144.753 1.00 118.81 ? 163 LEU B O   1 
ATOM   3186 C  CB  . LEU B 1 163 ? 130.856 121.888 142.721 1.00 118.14 ? 163 LEU B CB  1 
ATOM   3187 C  CG  . LEU B 1 163 ? 129.333 121.803 142.635 1.00 121.93 ? 163 LEU B CG  1 
ATOM   3188 C  CD1 . LEU B 1 163 ? 128.879 120.356 142.667 1.00 121.10 ? 163 LEU B CD1 1 
ATOM   3189 C  CD2 . LEU B 1 163 ? 128.694 122.589 143.762 1.00 117.43 ? 163 LEU B CD2 1 
ATOM   3190 N  N   . ALA B 1 164 ? 133.844 122.930 142.721 1.00 122.53 ? 164 ALA B N   1 
ATOM   3191 C  CA  . ALA B 1 164 ? 135.210 122.855 143.229 1.00 117.74 ? 164 ALA B CA  1 
ATOM   3192 C  C   . ALA B 1 164 ? 135.683 124.204 143.752 1.00 123.18 ? 164 ALA B C   1 
ATOM   3193 O  O   . ALA B 1 164 ? 136.355 124.276 144.787 1.00 127.92 ? 164 ALA B O   1 
ATOM   3194 C  CB  . ALA B 1 164 ? 136.148 122.347 142.137 1.00 119.20 ? 164 ALA B CB  1 
ATOM   3195 N  N   . PHE B 1 165 ? 135.353 125.285 143.043 1.00 133.06 ? 165 PHE B N   1 
ATOM   3196 C  CA  . PHE B 1 165 ? 135.739 126.615 143.501 1.00 129.91 ? 165 PHE B CA  1 
ATOM   3197 C  C   . PHE B 1 165 ? 135.077 126.954 144.828 1.00 130.49 ? 165 PHE B C   1 
ATOM   3198 O  O   . PHE B 1 165 ? 135.711 127.530 145.718 1.00 129.09 ? 165 PHE B O   1 
ATOM   3199 C  CB  . PHE B 1 165 ? 135.384 127.655 142.442 1.00 129.44 ? 165 PHE B CB  1 
ATOM   3200 C  CG  . PHE B 1 165 ? 135.986 129.002 142.693 1.00 136.73 ? 165 PHE B CG  1 
ATOM   3201 C  CD1 . PHE B 1 165 ? 137.322 129.237 142.422 1.00 134.57 ? 165 PHE B CD1 1 
ATOM   3202 C  CD2 . PHE B 1 165 ? 135.217 130.036 143.197 1.00 135.73 ? 165 PHE B CD2 1 
ATOM   3203 C  CE1 . PHE B 1 165 ? 137.880 130.478 142.651 1.00 134.39 ? 165 PHE B CE1 1 
ATOM   3204 C  CE2 . PHE B 1 165 ? 135.768 131.278 143.428 1.00 134.56 ? 165 PHE B CE2 1 
ATOM   3205 C  CZ  . PHE B 1 165 ? 137.101 131.500 143.155 1.00 135.06 ? 165 PHE B CZ  1 
ATOM   3206 N  N   . VAL B 1 166 ? 133.799 126.603 144.980 1.00 125.41 ? 166 VAL B N   1 
ATOM   3207 C  CA  . VAL B 1 166 ? 133.117 126.818 146.252 1.00 121.08 ? 166 VAL B CA  1 
ATOM   3208 C  C   . VAL B 1 166 ? 133.757 125.972 147.346 1.00 122.21 ? 166 VAL B C   1 
ATOM   3209 O  O   . VAL B 1 166 ? 133.861 126.397 148.501 1.00 122.64 ? 166 VAL B O   1 
ATOM   3210 C  CB  . VAL B 1 166 ? 131.612 126.524 146.103 1.00 123.16 ? 166 VAL B CB  1 
ATOM   3211 C  CG1 . VAL B 1 166 ? 131.002 126.107 147.429 1.00 119.57 ? 166 VAL B CG1 1 
ATOM   3212 C  CG2 . VAL B 1 166 ? 130.894 127.740 145.549 1.00 123.33 ? 166 VAL B CG2 1 
ATOM   3213 N  N   . ARG B 1 167 ? 134.196 124.762 147.000 1.00 127.34 ? 167 ARG B N   1 
ATOM   3214 C  CA  . ARG B 1 167 ? 134.867 123.914 147.979 1.00 124.38 ? 167 ARG B CA  1 
ATOM   3215 C  C   . ARG B 1 167 ? 136.190 124.520 148.431 1.00 125.73 ? 167 ARG B C   1 
ATOM   3216 O  O   . ARG B 1 167 ? 136.546 124.432 149.610 1.00 126.41 ? 167 ARG B O   1 
ATOM   3217 C  CB  . ARG B 1 167 ? 135.094 122.521 147.397 1.00 125.67 ? 167 ARG B CB  1 
ATOM   3218 C  CG  . ARG B 1 167 ? 133.962 121.547 147.654 1.00 125.63 ? 167 ARG B CG  1 
ATOM   3219 C  CD  . ARG B 1 167 ? 134.406 120.120 147.400 1.00 126.06 ? 167 ARG B CD  1 
ATOM   3220 N  NE  . ARG B 1 167 ? 133.354 119.160 147.706 1.00 125.81 ? 167 ARG B NE  1 
ATOM   3221 C  CZ  . ARG B 1 167 ? 133.529 117.847 147.739 1.00 127.82 ? 167 ARG B CZ  1 
ATOM   3222 N  NH1 . ARG B 1 167 ? 134.708 117.301 147.495 1.00 127.22 ? 167 ARG B NH1 1 
ATOM   3223 N  NH2 . ARG B 1 167 ? 132.496 117.063 148.029 1.00 128.10 ? 167 ARG B NH2 1 
ATOM   3224 N  N   . LEU B 1 168 ? 136.936 125.127 147.506 1.00 129.50 ? 168 LEU B N   1 
ATOM   3225 C  CA  . LEU B 1 168 ? 138.283 125.592 147.829 1.00 132.15 ? 168 LEU B CA  1 
ATOM   3226 C  C   . LEU B 1 168 ? 138.264 126.709 148.867 1.00 137.07 ? 168 LEU B C   1 
ATOM   3227 O  O   . LEU B 1 168 ? 139.088 126.720 149.788 1.00 138.75 ? 168 LEU B O   1 
ATOM   3228 C  CB  . LEU B 1 168 ? 138.995 126.049 146.558 1.00 134.74 ? 168 LEU B CB  1 
ATOM   3229 C  CG  . LEU B 1 168 ? 139.806 124.968 145.844 1.00 132.64 ? 168 LEU B CG  1 
ATOM   3230 C  CD1 . LEU B 1 168 ? 140.646 125.568 144.733 1.00 131.57 ? 168 LEU B CD1 1 
ATOM   3231 C  CD2 . LEU B 1 168 ? 140.681 124.220 146.832 1.00 130.48 ? 168 LEU B CD2 1 
ATOM   3232 N  N   . LEU B 1 169 ? 137.341 127.657 148.736 1.00 140.50 ? 169 LEU B N   1 
ATOM   3233 C  CA  . LEU B 1 169 ? 137.221 128.781 149.657 1.00 136.32 ? 169 LEU B CA  1 
ATOM   3234 C  C   . LEU B 1 169 ? 135.893 128.689 150.397 1.00 140.80 ? 169 LEU B C   1 
ATOM   3235 O  O   . LEU B 1 169 ? 134.849 128.467 149.779 1.00 141.96 ? 169 LEU B O   1 
ATOM   3236 C  CB  . LEU B 1 169 ? 137.391 130.106 148.904 1.00 135.06 ? 169 LEU B CB  1 
ATOM   3237 C  CG  . LEU B 1 169 ? 136.500 130.462 147.711 1.00 138.44 ? 169 LEU B CG  1 
ATOM   3238 C  CD1 . LEU B 1 169 ? 135.216 131.143 148.111 1.00 135.74 ? 169 LEU B CD1 1 
ATOM   3239 C  CD2 . LEU B 1 169 ? 137.281 131.328 146.737 1.00 138.37 ? 169 LEU B CD2 1 
ATOM   3240 N  N   . HIS B 1 170 ? 135.939 128.889 151.716 1.00 149.72 ? 170 HIS B N   1 
ATOM   3241 C  CA  . HIS B 1 170 ? 134.997 128.289 152.664 1.00 148.75 ? 170 HIS B CA  1 
ATOM   3242 C  C   . HIS B 1 170 ? 135.020 126.763 152.531 1.00 146.54 ? 170 HIS B C   1 
ATOM   3243 O  O   . HIS B 1 170 ? 134.050 126.115 152.135 1.00 147.06 ? 170 HIS B O   1 
ATOM   3244 C  CB  . HIS B 1 170 ? 133.561 128.822 152.531 1.00 146.42 ? 170 HIS B CB  1 
ATOM   3245 C  CG  . HIS B 1 170 ? 133.455 130.200 151.960 1.00 149.78 ? 170 HIS B CG  1 
ATOM   3246 N  ND1 . HIS B 1 170 ? 133.081 130.441 150.656 1.00 150.36 ? 170 HIS B ND1 1 
ATOM   3247 C  CD2 . HIS B 1 170 ? 133.647 131.413 152.528 1.00 148.29 ? 170 HIS B CD2 1 
ATOM   3248 C  CE1 . HIS B 1 170 ? 133.050 131.745 150.445 1.00 151.40 ? 170 HIS B CE1 1 
ATOM   3249 N  NE2 . HIS B 1 170 ? 133.397 132.357 151.563 1.00 151.18 ? 170 HIS B NE2 1 
ATOM   3250 N  N   . SER B 1 171 ? 136.179 126.209 152.886 1.00 142.55 ? 171 SER B N   1 
ATOM   3251 C  CA  . SER B 1 171 ? 136.435 124.776 152.763 1.00 145.52 ? 171 SER B CA  1 
ATOM   3252 C  C   . SER B 1 171 ? 135.649 124.039 153.843 1.00 144.80 ? 171 SER B C   1 
ATOM   3253 O  O   . SER B 1 171 ? 136.175 123.629 154.880 1.00 145.63 ? 171 SER B O   1 
ATOM   3254 C  CB  . SER B 1 171 ? 137.927 124.492 152.871 1.00 146.86 ? 171 SER B CB  1 
ATOM   3255 O  OG  . SER B 1 171 ? 138.636 125.106 151.811 1.00 148.64 ? 171 SER B OG  1 
ATOM   3256 N  N   . ASP B 1 172 ? 134.356 123.868 153.585 1.00 144.34 ? 172 ASP B N   1 
ATOM   3257 C  CA  . ASP B 1 172 ? 133.447 123.175 154.493 1.00 148.54 ? 172 ASP B CA  1 
ATOM   3258 C  C   . ASP B 1 172 ? 132.920 121.942 153.764 1.00 149.99 ? 172 ASP B C   1 
ATOM   3259 O  O   . ASP B 1 172 ? 131.878 121.990 153.107 1.00 149.56 ? 172 ASP B O   1 
ATOM   3260 C  CB  . ASP B 1 172 ? 132.315 124.096 154.945 1.00 149.20 ? 172 ASP B CB  1 
ATOM   3261 C  CG  . ASP B 1 172 ? 131.204 123.349 155.655 1.00 152.02 ? 172 ASP B CG  1 
ATOM   3262 O  OD1 . ASP B 1 172 ? 131.514 122.508 156.524 1.00 152.90 ? 172 ASP B OD1 1 
ATOM   3263 O  OD2 . ASP B 1 172 ? 130.022 123.602 155.343 1.00 148.52 ? 172 ASP B OD2 1 
ATOM   3264 N  N   . TYR B 1 173 ? 133.655 120.839 153.876 1.00 137.30 ? 173 TYR B N   1 
ATOM   3265 C  CA  . TYR B 1 173 ? 133.260 119.576 153.270 1.00 133.09 ? 173 TYR B CA  1 
ATOM   3266 C  C   . TYR B 1 173 ? 134.096 118.465 153.880 1.00 131.91 ? 173 TYR B C   1 
ATOM   3267 O  O   . TYR B 1 173 ? 135.235 118.689 154.297 1.00 136.01 ? 173 TYR B O   1 
ATOM   3268 C  CB  . TYR B 1 173 ? 133.434 119.598 151.747 1.00 130.65 ? 173 TYR B CB  1 
ATOM   3269 C  CG  . TYR B 1 173 ? 134.846 119.882 151.290 1.00 129.83 ? 173 TYR B CG  1 
ATOM   3270 C  CD1 . TYR B 1 173 ? 135.280 121.182 151.090 1.00 130.38 ? 173 TYR B CD1 1 
ATOM   3271 C  CD2 . TYR B 1 173 ? 135.741 118.851 151.051 1.00 129.69 ? 173 TYR B CD2 1 
ATOM   3272 C  CE1 . TYR B 1 173 ? 136.565 121.447 150.671 1.00 134.91 ? 173 TYR B CE1 1 
ATOM   3273 C  CE2 . TYR B 1 173 ? 137.028 119.107 150.632 1.00 128.28 ? 173 TYR B CE2 1 
ATOM   3274 C  CZ  . TYR B 1 173 ? 137.434 120.407 150.444 1.00 133.17 ? 173 TYR B CZ  1 
ATOM   3275 O  OH  . TYR B 1 173 ? 138.716 120.671 150.027 1.00 132.97 ? 173 TYR B OH  1 
ATOM   3276 N  N   . HIS B 1 174 ? 133.519 117.270 153.925 1.00 126.88 ? 174 HIS B N   1 
ATOM   3277 C  CA  . HIS B 1 174 ? 134.208 116.082 154.400 1.00 129.62 ? 174 HIS B CA  1 
ATOM   3278 C  C   . HIS B 1 174 ? 134.187 115.026 153.308 1.00 132.04 ? 174 HIS B C   1 
ATOM   3279 O  O   . HIS B 1 174 ? 133.172 114.841 152.630 1.00 133.42 ? 174 HIS B O   1 
ATOM   3280 C  CB  . HIS B 1 174 ? 133.568 115.537 155.680 1.00 131.86 ? 174 HIS B CB  1 
ATOM   3281 C  CG  . HIS B 1 174 ? 132.184 115.002 155.484 1.00 134.66 ? 174 HIS B CG  1 
ATOM   3282 N  ND1 . HIS B 1 174 ? 131.100 115.815 155.238 1.00 135.07 ? 174 HIS B ND1 1 
ATOM   3283 C  CD2 . HIS B 1 174 ? 131.708 113.734 155.501 1.00 134.79 ? 174 HIS B CD2 1 
ATOM   3284 C  CE1 . HIS B 1 174 ? 130.015 115.072 155.110 1.00 135.67 ? 174 HIS B CE1 1 
ATOM   3285 N  NE2 . HIS B 1 174 ? 130.357 113.805 155.265 1.00 137.31 ? 174 HIS B NE2 1 
ATOM   3286 N  N   . ILE B 1 175 ? 135.313 114.344 153.133 1.00 128.72 ? 175 ILE B N   1 
ATOM   3287 C  CA  . ILE B 1 175 ? 135.472 113.335 152.094 1.00 128.00 ? 175 ILE B CA  1 
ATOM   3288 C  C   . ILE B 1 175 ? 135.769 112.007 152.770 1.00 129.50 ? 175 ILE B C   1 
ATOM   3289 O  O   . ILE B 1 175 ? 136.731 111.898 153.539 1.00 127.82 ? 175 ILE B O   1 
ATOM   3290 C  CB  . ILE B 1 175 ? 136.587 113.708 151.107 1.00 124.76 ? 175 ILE B CB  1 
ATOM   3291 C  CG1 . ILE B 1 175 ? 136.240 115.013 150.393 1.00 125.58 ? 175 ILE B CG1 1 
ATOM   3292 C  CG2 . ILE B 1 175 ? 136.809 112.588 150.110 1.00 126.94 ? 175 ILE B CG2 1 
ATOM   3293 C  CD1 . ILE B 1 175 ? 137.188 115.365 149.285 1.00 125.59 ? 175 ILE B CD1 1 
ATOM   3294 N  N   . GLU B 1 176 ? 134.946 111.002 152.485 1.00 133.21 ? 176 GLU B N   1 
ATOM   3295 C  CA  . GLU B 1 176 ? 135.152 109.667 153.032 1.00 131.87 ? 176 GLU B CA  1 
ATOM   3296 C  C   . GLU B 1 176 ? 136.306 109.014 152.286 1.00 134.44 ? 176 GLU B C   1 
ATOM   3297 O  O   . GLU B 1 176 ? 136.194 108.711 151.095 1.00 138.66 ? 176 GLU B O   1 
ATOM   3298 C  CB  . GLU B 1 176 ? 133.875 108.841 152.916 1.00 133.38 ? 176 GLU B CB  1 
ATOM   3299 C  CG  . GLU B 1 176 ? 132.605 109.666 152.995 1.00 137.11 ? 176 GLU B CG  1 
ATOM   3300 C  CD  . GLU B 1 176 ? 132.174 109.931 154.422 1.00 141.63 ? 176 GLU B CD  1 
ATOM   3301 O  OE1 . GLU B 1 176 ? 132.799 109.371 155.346 1.00 140.81 ? 176 GLU B OE1 1 
ATOM   3302 O  OE2 . GLU B 1 176 ? 131.211 110.702 154.622 1.00 138.20 ? 176 GLU B OE2 1 
ATOM   3303 N  N   . GLY B 1 177 ? 137.422 108.804 152.985 1.00 131.52 ? 177 GLY B N   1 
ATOM   3304 C  CA  . GLY B 1 177 ? 138.598 108.259 152.330 1.00 132.42 ? 177 GLY B CA  1 
ATOM   3305 C  C   . GLY B 1 177 ? 138.396 106.841 151.835 1.00 133.53 ? 177 GLY B C   1 
ATOM   3306 O  O   . GLY B 1 177 ? 138.808 106.498 150.725 1.00 134.61 ? 177 GLY B O   1 
ATOM   3307 N  N   . GLY B 1 178 ? 137.761 105.999 152.650 1.00 128.98 ? 178 GLY B N   1 
ATOM   3308 C  CA  . GLY B 1 178 ? 137.579 104.610 152.260 1.00 126.92 ? 178 GLY B CA  1 
ATOM   3309 C  C   . GLY B 1 178 ? 136.701 104.458 151.034 1.00 125.54 ? 178 GLY B C   1 
ATOM   3310 O  O   . GLY B 1 178 ? 137.032 103.717 150.106 1.00 126.34 ? 178 GLY B O   1 
ATOM   3311 N  N   . ALA B 1 179 ? 135.570 105.166 151.011 1.00 117.16 ? 179 ALA B N   1 
ATOM   3312 C  CA  . ALA B 1 179 ? 134.665 105.069 149.871 1.00 118.02 ? 179 ALA B CA  1 
ATOM   3313 C  C   . ALA B 1 179 ? 135.318 105.595 148.601 1.00 121.23 ? 179 ALA B C   1 
ATOM   3314 O  O   . ALA B 1 179 ? 135.196 104.985 147.532 1.00 124.30 ? 179 ALA B O   1 
ATOM   3315 C  CB  . ALA B 1 179 ? 133.372 105.828 150.163 1.00 117.61 ? 179 ALA B CB  1 
ATOM   3316 N  N   . MET B 1 180 ? 136.018 106.726 148.699 1.00 122.93 ? 180 MET B N   1 
ATOM   3317 C  CA  . MET B 1 180 ? 136.674 107.294 147.527 1.00 119.29 ? 180 MET B CA  1 
ATOM   3318 C  C   . MET B 1 180 ? 137.771 106.374 147.012 1.00 120.18 ? 180 MET B C   1 
ATOM   3319 O  O   . MET B 1 180 ? 137.900 106.169 145.800 1.00 119.71 ? 180 MET B O   1 
ATOM   3320 C  CB  . MET B 1 180 ? 137.238 108.673 147.863 1.00 118.81 ? 180 MET B CB  1 
ATOM   3321 C  CG  . MET B 1 180 ? 137.743 109.450 146.665 1.00 123.03 ? 180 MET B CG  1 
ATOM   3322 S  SD  . MET B 1 180 ? 138.556 110.986 147.137 1.00 132.71 ? 180 MET B SD  1 
ATOM   3323 C  CE  . MET B 1 180 ? 139.384 111.410 145.611 1.00 123.61 ? 180 MET B CE  1 
ATOM   3324 N  N   . LEU B 1 181 ? 138.567 105.805 147.919 1.00 116.16 ? 181 LEU B N   1 
ATOM   3325 C  CA  . LEU B 1 181 ? 139.616 104.882 147.504 1.00 114.58 ? 181 LEU B CA  1 
ATOM   3326 C  C   . LEU B 1 181 ? 139.030 103.641 146.846 1.00 120.82 ? 181 LEU B C   1 
ATOM   3327 O  O   . LEU B 1 181 ? 139.542 103.173 145.822 1.00 124.60 ? 181 LEU B O   1 
ATOM   3328 C  CB  . LEU B 1 181 ? 140.478 104.498 148.704 1.00 112.18 ? 181 LEU B CB  1 
ATOM   3329 C  CG  . LEU B 1 181 ? 141.631 103.533 148.434 1.00 111.68 ? 181 LEU B CG  1 
ATOM   3330 C  CD1 . LEU B 1 181 ? 142.451 103.999 147.250 1.00 111.56 ? 181 LEU B CD1 1 
ATOM   3331 C  CD2 . LEU B 1 181 ? 142.503 103.396 149.664 1.00 112.99 ? 181 LEU B CD2 1 
ATOM   3332 N  N   . LEU B 1 182 ? 137.955 103.093 147.417 1.00 114.90 ? 182 LEU B N   1 
ATOM   3333 C  CA  . LEU B 1 182 ? 137.334 101.913 146.829 1.00 110.98 ? 182 LEU B CA  1 
ATOM   3334 C  C   . LEU B 1 182 ? 136.776 102.215 145.445 1.00 110.33 ? 182 LEU B C   1 
ATOM   3335 O  O   . LEU B 1 182 ? 136.958 101.427 144.510 1.00 116.26 ? 182 LEU B O   1 
ATOM   3336 C  CB  . LEU B 1 182 ? 136.232 101.389 147.746 1.00 112.46 ? 182 LEU B CB  1 
ATOM   3337 C  CG  . LEU B 1 182 ? 135.644 100.035 147.356 1.00 114.53 ? 182 LEU B CG  1 
ATOM   3338 C  CD1 . LEU B 1 182 ? 136.584 98.915  147.760 1.00 111.58 ? 182 LEU B CD1 1 
ATOM   3339 C  CD2 . LEU B 1 182 ? 134.276 99.847  147.984 1.00 113.94 ? 182 LEU B CD2 1 
ATOM   3340 N  N   . THR B 1 183 ? 136.100 103.355 145.292 1.00 104.56 ? 183 THR B N   1 
ATOM   3341 C  CA  . THR B 1 183 ? 135.548 103.709 143.989 1.00 100.38 ? 183 THR B CA  1 
ATOM   3342 C  C   . THR B 1 183 ? 136.651 103.925 142.963 1.00 110.24 ? 183 THR B C   1 
ATOM   3343 O  O   . THR B 1 183 ? 136.525 103.500 141.809 1.00 122.97 ? 183 THR B O   1 
ATOM   3344 C  CB  . THR B 1 183 ? 134.677 104.956 144.107 1.00 106.50 ? 183 THR B CB  1 
ATOM   3345 O  OG1 . THR B 1 183 ? 133.725 104.775 145.160 1.00 111.37 ? 183 THR B OG1 1 
ATOM   3346 C  CG2 . THR B 1 183 ? 133.941 105.209 142.806 1.00 106.26 ? 183 THR B CG2 1 
ATOM   3347 N  N   . ALA B 1 184 ? 137.741 104.585 143.360 1.00 109.94 ? 184 ALA B N   1 
ATOM   3348 C  CA  . ALA B 1 184 ? 138.845 104.811 142.434 1.00 110.48 ? 184 ALA B CA  1 
ATOM   3349 C  C   . ALA B 1 184 ? 139.503 103.500 142.023 1.00 116.51 ? 184 ALA B C   1 
ATOM   3350 O  O   . ALA B 1 184 ? 139.850 103.312 140.851 1.00 120.55 ? 184 ALA B O   1 
ATOM   3351 C  CB  . ALA B 1 184 ? 139.868 105.753 143.060 1.00 116.53 ? 184 ALA B CB  1 
ATOM   3352 N  N   . SER B 1 185 ? 139.690 102.583 142.975 1.00 110.45 ? 185 SER B N   1 
ATOM   3353 C  CA  . SER B 1 185 ? 140.261 101.283 142.640 1.00 111.61 ? 185 SER B CA  1 
ATOM   3354 C  C   . SER B 1 185 ? 139.348 100.509 141.699 1.00 114.05 ? 185 SER B C   1 
ATOM   3355 O  O   . SER B 1 185 ? 139.818 99.873  140.748 1.00 113.89 ? 185 SER B O   1 
ATOM   3356 C  CB  . SER B 1 185 ? 140.520 100.481 143.913 1.00 111.93 ? 185 SER B CB  1 
ATOM   3357 O  OG  . SER B 1 185 ? 141.209 101.261 144.871 1.00 117.13 ? 185 SER B OG  1 
ATOM   3358 N  N   . ILE B 1 186 ? 138.038 100.554 141.949 1.00 116.28 ? 186 ILE B N   1 
ATOM   3359 C  CA  . ILE B 1 186 ? 137.089 99.874  141.074 1.00 111.37 ? 186 ILE B CA  1 
ATOM   3360 C  C   . ILE B 1 186 ? 137.142 100.465 139.672 1.00 112.60 ? 186 ILE B C   1 
ATOM   3361 O  O   . ILE B 1 186 ? 137.119 99.736  138.675 1.00 122.33 ? 186 ILE B O   1 
ATOM   3362 C  CB  . ILE B 1 186 ? 135.670 99.945  141.669 1.00 113.87 ? 186 ILE B CB  1 
ATOM   3363 C  CG1 . ILE B 1 186 ? 135.545 99.007  142.870 1.00 113.52 ? 186 ILE B CG1 1 
ATOM   3364 C  CG2 . ILE B 1 186 ? 134.630 99.600  140.621 1.00 114.11 ? 186 ILE B CG2 1 
ATOM   3365 C  CD1 . ILE B 1 186 ? 136.120 97.633  142.634 1.00 114.08 ? 186 ILE B CD1 1 
ATOM   3366 N  N   . ALA B 1 187 ? 137.216 101.794 139.573 1.00 107.99 ? 187 ALA B N   1 
ATOM   3367 C  CA  . ALA B 1 187 ? 137.281 102.439 138.266 1.00 109.81 ? 187 ALA B CA  1 
ATOM   3368 C  C   . ALA B 1 187 ? 138.559 102.068 137.524 1.00 115.79 ? 187 ALA B C   1 
ATOM   3369 O  O   . ALA B 1 187 ? 138.532 101.811 136.314 1.00 122.19 ? 187 ALA B O   1 
ATOM   3370 C  CB  . ALA B 1 187 ? 137.172 103.953 138.424 1.00 112.70 ? 187 ALA B CB  1 
ATOM   3371 N  N   . VAL B 1 188 ? 139.691 102.042 138.229 1.00 116.32 ? 188 VAL B N   1 
ATOM   3372 C  CA  . VAL B 1 188 ? 140.950 101.667 137.590 1.00 117.80 ? 188 VAL B CA  1 
ATOM   3373 C  C   . VAL B 1 188 ? 140.891 100.226 137.101 1.00 122.13 ? 188 VAL B C   1 
ATOM   3374 O  O   . VAL B 1 188 ? 141.324 99.914  135.983 1.00 127.93 ? 188 VAL B O   1 
ATOM   3375 C  CB  . VAL B 1 188 ? 142.127 101.896 138.554 1.00 116.12 ? 188 VAL B CB  1 
ATOM   3376 C  CG1 . VAL B 1 188 ? 143.333 101.083 138.127 1.00 115.30 ? 188 VAL B CG1 1 
ATOM   3377 C  CG2 . VAL B 1 188 ? 142.478 103.367 138.610 1.00 117.24 ? 188 VAL B CG2 1 
ATOM   3378 N  N   . CYS B 1 189 ? 140.351 99.325  137.924 1.00 123.65 ? 189 CYS B N   1 
ATOM   3379 C  CA  . CYS B 1 189 ? 140.234 97.930  137.513 1.00 122.03 ? 189 CYS B CA  1 
ATOM   3380 C  C   . CYS B 1 189 ? 139.305 97.781  136.315 1.00 125.84 ? 189 CYS B C   1 
ATOM   3381 O  O   . CYS B 1 189 ? 139.573 96.985  135.409 1.00 129.79 ? 189 CYS B O   1 
ATOM   3382 C  CB  . CYS B 1 189 ? 139.745 97.078  138.683 1.00 126.18 ? 189 CYS B CB  1 
ATOM   3383 S  SG  . CYS B 1 189 ? 141.049 96.569  139.822 1.00 142.61 ? 189 CYS B SG  1 
ATOM   3384 N  N   . ALA B 1 190 ? 138.205 98.536  136.295 1.00 116.87 ? 190 ALA B N   1 
ATOM   3385 C  CA  . ALA B 1 190 ? 137.287 98.475  135.163 1.00 111.02 ? 190 ALA B CA  1 
ATOM   3386 C  C   . ALA B 1 190 ? 137.953 98.967  133.887 1.00 116.63 ? 190 ALA B C   1 
ATOM   3387 O  O   . ALA B 1 190 ? 137.774 98.375  132.817 1.00 127.72 ? 190 ALA B O   1 
ATOM   3388 C  CB  . ALA B 1 190 ? 136.031 99.291  135.460 1.00 107.14 ? 190 ALA B CB  1 
ATOM   3389 N  N   . ASN B 1 191 ? 138.723 100.051 133.977 1.00 117.22 ? 191 ASN B N   1 
ATOM   3390 C  CA  . ASN B 1 191 ? 139.427 100.548 132.800 1.00 117.10 ? 191 ASN B CA  1 
ATOM   3391 C  C   . ASN B 1 191 ? 140.462 99.543  132.312 1.00 119.91 ? 191 ASN B C   1 
ATOM   3392 O  O   . ASN B 1 191 ? 140.618 99.338  131.103 1.00 128.46 ? 191 ASN B O   1 
ATOM   3393 C  CB  . ASN B 1 191 ? 140.082 101.891 133.106 1.00 118.30 ? 191 ASN B CB  1 
ATOM   3394 C  CG  . ASN B 1 191 ? 139.203 103.060 132.731 1.00 120.90 ? 191 ASN B CG  1 
ATOM   3395 O  OD1 . ASN B 1 191 ? 138.977 103.964 133.533 1.00 124.74 ? 191 ASN B OD1 1 
ATOM   3396 N  ND2 . ASN B 1 191 ? 138.695 103.047 131.507 1.00 123.50 ? 191 ASN B ND2 1 
ATOM   3397 N  N   . LEU B 1 192 ? 141.180 98.906  133.239 1.00 119.70 ? 192 LEU B N   1 
ATOM   3398 C  CA  . LEU B 1 192 ? 142.147 97.886  132.846 1.00 118.89 ? 192 LEU B CA  1 
ATOM   3399 C  C   . LEU B 1 192 ? 141.461 96.709  132.165 1.00 126.04 ? 192 LEU B C   1 
ATOM   3400 O  O   . LEU B 1 192 ? 141.957 96.187  131.160 1.00 135.77 ? 192 LEU B O   1 
ATOM   3401 C  CB  . LEU B 1 192 ? 142.934 97.412  134.065 1.00 121.17 ? 192 LEU B CB  1 
ATOM   3402 C  CG  . LEU B 1 192 ? 144.179 98.222  134.416 1.00 124.50 ? 192 LEU B CG  1 
ATOM   3403 C  CD1 . LEU B 1 192 ? 144.655 97.885  135.816 1.00 125.96 ? 192 LEU B CD1 1 
ATOM   3404 C  CD2 . LEU B 1 192 ? 145.275 97.971  133.400 1.00 126.02 ? 192 LEU B CD2 1 
ATOM   3405 N  N   . LEU B 1 193 ? 140.321 96.273  132.702 1.00 122.97 ? 193 LEU B N   1 
ATOM   3406 C  CA  . LEU B 1 193 ? 139.593 95.167  132.093 1.00 122.02 ? 193 LEU B CA  1 
ATOM   3407 C  C   . LEU B 1 193 ? 139.091 95.536  130.704 1.00 125.00 ? 193 LEU B C   1 
ATOM   3408 O  O   . LEU B 1 193 ? 139.158 94.722  129.775 1.00 127.36 ? 193 LEU B O   1 
ATOM   3409 C  CB  . LEU B 1 193 ? 138.432 94.751  132.994 1.00 121.97 ? 193 LEU B CB  1 
ATOM   3410 C  CG  . LEU B 1 193 ? 137.406 93.788  132.401 1.00 128.23 ? 193 LEU B CG  1 
ATOM   3411 C  CD1 . LEU B 1 193 ? 137.970 92.381  132.344 1.00 127.15 ? 193 LEU B CD1 1 
ATOM   3412 C  CD2 . LEU B 1 193 ? 136.121 93.821  133.209 1.00 125.98 ? 193 LEU B CD2 1 
ATOM   3413 N  N   . MET B 1 194 ? 138.585 96.760  130.541 1.00 125.04 ? 194 MET B N   1 
ATOM   3414 C  CA  . MET B 1 194 ? 138.139 97.205  129.226 1.00 120.67 ? 194 MET B CA  1 
ATOM   3415 C  C   . MET B 1 194 ? 139.294 97.238  128.236 1.00 126.97 ? 194 MET B C   1 
ATOM   3416 O  O   . MET B 1 194 ? 139.146 96.816  127.083 1.00 137.23 ? 194 MET B O   1 
ATOM   3417 C  CB  . MET B 1 194 ? 137.487 98.582  129.329 1.00 121.80 ? 194 MET B CB  1 
ATOM   3418 C  CG  . MET B 1 194 ? 136.064 98.559  129.848 1.00 126.42 ? 194 MET B CG  1 
ATOM   3419 S  SD  . MET B 1 194 ? 135.652 100.035 130.795 1.00 141.16 ? 194 MET B SD  1 
ATOM   3420 C  CE  . MET B 1 194 ? 135.322 101.202 129.480 1.00 128.38 ? 194 MET B CE  1 
ATOM   3421 N  N   . ALA B 1 195 ? 140.455 97.739  128.666 1.00 126.32 ? 195 ALA B N   1 
ATOM   3422 C  CA  . ALA B 1 195 ? 141.616 97.773  127.782 1.00 123.55 ? 195 ALA B CA  1 
ATOM   3423 C  C   . ALA B 1 195 ? 142.050 96.369  127.388 1.00 127.32 ? 195 ALA B C   1 
ATOM   3424 O  O   . ALA B 1 195 ? 142.380 96.117  126.224 1.00 135.09 ? 195 ALA B O   1 
ATOM   3425 C  CB  . ALA B 1 195 ? 142.766 98.520  128.453 1.00 122.98 ? 195 ALA B CB  1 
ATOM   3426 N  N   . PHE B 1 196 ? 142.060 95.440  128.347 1.00 128.43 ? 196 PHE B N   1 
ATOM   3427 C  CA  . PHE B 1 196 ? 142.439 94.065  128.037 1.00 129.88 ? 196 PHE B CA  1 
ATOM   3428 C  C   . PHE B 1 196 ? 141.461 93.431  127.056 1.00 132.99 ? 196 PHE B C   1 
ATOM   3429 O  O   . PHE B 1 196 ? 141.873 92.748  126.110 1.00 136.06 ? 196 PHE B O   1 
ATOM   3430 C  CB  . PHE B 1 196 ? 142.517 93.245  129.323 1.00 129.71 ? 196 PHE B CB  1 
ATOM   3431 C  CG  . PHE B 1 196 ? 142.752 91.783  129.094 1.00 132.75 ? 196 PHE B CG  1 
ATOM   3432 C  CD1 . PHE B 1 196 ? 143.972 91.331  128.626 1.00 132.52 ? 196 PHE B CD1 1 
ATOM   3433 C  CD2 . PHE B 1 196 ? 141.754 90.861  129.349 1.00 132.37 ? 196 PHE B CD2 1 
ATOM   3434 C  CE1 . PHE B 1 196 ? 144.192 89.985  128.416 1.00 132.46 ? 196 PHE B CE1 1 
ATOM   3435 C  CE2 . PHE B 1 196 ? 141.967 89.514  129.140 1.00 133.54 ? 196 PHE B CE2 1 
ATOM   3436 C  CZ  . PHE B 1 196 ? 143.188 89.076  128.673 1.00 135.87 ? 196 PHE B CZ  1 
ATOM   3437 N  N   . VAL B 1 197 ? 140.161 93.650  127.263 1.00 128.57 ? 197 VAL B N   1 
ATOM   3438 C  CA  . VAL B 1 197 ? 139.157 93.091  126.363 1.00 128.64 ? 197 VAL B CA  1 
ATOM   3439 C  C   . VAL B 1 197 ? 139.318 93.665  124.962 1.00 128.40 ? 197 VAL B C   1 
ATOM   3440 O  O   . VAL B 1 197 ? 139.238 92.939  123.964 1.00 129.91 ? 197 VAL B O   1 
ATOM   3441 C  CB  . VAL B 1 197 ? 137.745 93.343  126.921 1.00 127.68 ? 197 VAL B CB  1 
ATOM   3442 C  CG1 . VAL B 1 197 ? 136.705 93.220  125.822 1.00 126.13 ? 197 VAL B CG1 1 
ATOM   3443 C  CG2 . VAL B 1 197 ? 137.447 92.377  128.051 1.00 127.27 ? 197 VAL B CG2 1 
ATOM   3444 N  N   . LEU B 1 198 ? 139.548 94.976  124.863 1.00 129.12 ? 198 LEU B N   1 
ATOM   3445 C  CA  . LEU B 1 198 ? 139.722 95.595  123.555 1.00 129.45 ? 198 LEU B CA  1 
ATOM   3446 C  C   . LEU B 1 198 ? 140.976 95.083  122.859 1.00 132.97 ? 198 LEU B C   1 
ATOM   3447 O  O   . LEU B 1 198 ? 140.969 94.861  121.643 1.00 137.17 ? 198 LEU B O   1 
ATOM   3448 C  CB  . LEU B 1 198 ? 139.764 97.113  123.696 1.00 129.49 ? 198 LEU B CB  1 
ATOM   3449 C  CG  . LEU B 1 198 ? 138.416 97.762  124.001 1.00 127.19 ? 198 LEU B CG  1 
ATOM   3450 C  CD1 . LEU B 1 198 ? 138.585 99.249  124.210 1.00 128.26 ? 198 LEU B CD1 1 
ATOM   3451 C  CD2 . LEU B 1 198 ? 137.432 97.486  122.883 1.00 130.83 ? 198 LEU B CD2 1 
ATOM   3452 N  N   . HIS B 1 199 ? 142.066 94.896  123.608 1.00 137.22 ? 199 HIS B N   1 
ATOM   3453 C  CA  . HIS B 1 199 ? 143.276 94.341  123.010 1.00 136.67 ? 199 HIS B CA  1 
ATOM   3454 C  C   . HIS B 1 199 ? 143.042 92.921  122.516 1.00 138.77 ? 199 HIS B C   1 
ATOM   3455 O  O   . HIS B 1 199 ? 143.527 92.542  121.444 1.00 141.20 ? 199 HIS B O   1 
ATOM   3456 C  CB  . HIS B 1 199 ? 144.427 94.370  124.013 1.00 137.35 ? 199 HIS B CB  1 
ATOM   3457 C  CG  . HIS B 1 199 ? 145.726 93.887  123.449 1.00 140.27 ? 199 HIS B CG  1 
ATOM   3458 N  ND1 . HIS B 1 199 ? 146.423 92.826  123.985 1.00 141.97 ? 199 HIS B ND1 1 
ATOM   3459 C  CD2 . HIS B 1 199 ? 146.455 94.320  122.394 1.00 139.88 ? 199 HIS B CD2 1 
ATOM   3460 C  CE1 . HIS B 1 199 ? 147.525 92.627  123.286 1.00 141.33 ? 199 HIS B CE1 1 
ATOM   3461 N  NE2 . HIS B 1 199 ? 147.569 93.521  122.315 1.00 139.26 ? 199 HIS B NE2 1 
ATOM   3462 N  N   . GLN B 1 200 ? 142.310 92.117  123.289 1.00 139.99 ? 200 GLN B N   1 
ATOM   3463 C  CA  . GLN B 1 200 ? 142.000 90.761  122.851 1.00 142.08 ? 200 GLN B CA  1 
ATOM   3464 C  C   . GLN B 1 200 ? 141.148 90.771  121.589 1.00 143.47 ? 200 GLN B C   1 
ATOM   3465 O  O   . GLN B 1 200 ? 141.371 89.971  120.673 1.00 142.73 ? 200 GLN B O   1 
ATOM   3466 C  CB  . GLN B 1 200 ? 141.296 89.995  123.969 1.00 139.59 ? 200 GLN B CB  1 
ATOM   3467 C  CG  . GLN B 1 200 ? 142.241 89.424  125.010 1.00 143.75 ? 200 GLN B CG  1 
ATOM   3468 C  CD  . GLN B 1 200 ? 143.571 89.002  124.420 1.00 146.16 ? 200 GLN B CD  1 
ATOM   3469 O  OE1 . GLN B 1 200 ? 144.565 89.720  124.523 1.00 143.37 ? 200 GLN B OE1 1 
ATOM   3470 N  NE2 . GLN B 1 200 ? 143.596 87.829  123.800 1.00 144.31 ? 200 GLN B NE2 1 
ATOM   3471 N  N   . ALA B 1 201 ? 140.171 91.668  121.521 1.00 138.88 ? 201 ALA B N   1 
ATOM   3472 C  CA  . ALA B 1 201 ? 139.313 91.769  120.347 1.00 135.40 ? 201 ALA B CA  1 
ATOM   3473 C  C   . ALA B 1 201 ? 139.861 92.792  119.359 1.00 131.72 ? 201 ALA B C   1 
ATOM   3474 O  O   . ALA B 1 201 ? 140.447 92.431  118.339 1.00 129.87 ? 201 ALA B O   1 
ATOM   3475 C  CB  . ALA B 1 201 ? 137.897 92.131  120.754 1.00 133.24 ? 201 ALA B CB  1 
ATOM   3476 N  N   . THR B 1 230 ? 141.174 100.447 113.508 1.00 146.58 ? 230 THR B N   1 
ATOM   3477 C  CA  . THR B 1 230 ? 139.837 100.917 113.169 1.00 148.87 ? 230 THR B CA  1 
ATOM   3478 C  C   . THR B 1 230 ? 139.088 101.376 114.413 1.00 147.51 ? 230 THR B C   1 
ATOM   3479 O  O   . THR B 1 230 ? 139.653 102.042 115.281 1.00 146.72 ? 230 THR B O   1 
ATOM   3480 C  CB  . THR B 1 230 ? 139.015 99.825  112.465 1.00 148.19 ? 230 THR B CB  1 
ATOM   3481 O  OG1 . THR B 1 230 ? 138.979 98.649  113.282 1.00 140.77 ? 230 THR B OG1 1 
ATOM   3482 C  CG2 . THR B 1 230 ? 139.631 99.482  111.120 1.00 146.36 ? 230 THR B CG2 1 
ATOM   3483 N  N   . SER B 1 231 ? 137.805 101.012 114.486 1.00 143.48 ? 231 SER B N   1 
ATOM   3484 C  CA  . SER B 1 231 ? 136.995 101.387 115.639 1.00 141.86 ? 231 SER B CA  1 
ATOM   3485 C  C   . SER B 1 231 ? 137.527 100.752 116.916 1.00 143.63 ? 231 SER B C   1 
ATOM   3486 O  O   . SER B 1 231 ? 137.545 101.390 117.974 1.00 145.62 ? 231 SER B O   1 
ATOM   3487 C  CB  . SER B 1 231 ? 135.539 100.989 115.408 1.00 139.57 ? 231 SER B CB  1 
ATOM   3488 O  OG  . SER B 1 231 ? 135.382 99.584  115.480 1.00 141.43 ? 231 SER B OG  1 
ATOM   3489 N  N   . VAL B 1 232 ? 137.966 99.495  116.839 1.00 135.94 ? 232 VAL B N   1 
ATOM   3490 C  CA  . VAL B 1 232 ? 138.497 98.821  118.021 1.00 131.84 ? 232 VAL B CA  1 
ATOM   3491 C  C   . VAL B 1 232 ? 139.776 99.499  118.498 1.00 133.86 ? 232 VAL B C   1 
ATOM   3492 O  O   . VAL B 1 232 ? 139.973 99.702  119.700 1.00 138.68 ? 232 VAL B O   1 
ATOM   3493 C  CB  . VAL B 1 232 ? 138.716 97.327  117.731 1.00 131.89 ? 232 VAL B CB  1 
ATOM   3494 C  CG1 . VAL B 1 232 ? 139.469 96.671  118.870 1.00 133.02 ? 232 VAL B CG1 1 
ATOM   3495 C  CG2 . VAL B 1 232 ? 137.384 96.638  117.513 1.00 132.31 ? 232 VAL B CG2 1 
ATOM   3496 N  N   . ARG B 1 233 ? 140.664 99.863  117.571 1.00 137.00 ? 233 ARG B N   1 
ATOM   3497 C  CA  . ARG B 1 233 ? 141.893 100.549 117.961 1.00 139.71 ? 233 ARG B CA  1 
ATOM   3498 C  C   . ARG B 1 233 ? 141.603 101.930 118.538 1.00 142.20 ? 233 ARG B C   1 
ATOM   3499 O  O   . ARG B 1 233 ? 142.259 102.363 119.498 1.00 142.43 ? 233 ARG B O   1 
ATOM   3500 C  CB  . ARG B 1 233 ? 142.838 100.649 116.764 1.00 138.79 ? 233 ARG B CB  1 
ATOM   3501 C  CG  . ARG B 1 233 ? 144.203 101.237 117.089 1.00 138.43 ? 233 ARG B CG  1 
ATOM   3502 C  CD  . ARG B 1 233 ? 145.047 100.293 117.931 1.00 139.24 ? 233 ARG B CD  1 
ATOM   3503 N  NE  . ARG B 1 233 ? 144.689 98.894  117.731 1.00 142.48 ? 233 ARG B NE  1 
ATOM   3504 C  CZ  . ARG B 1 233 ? 145.280 97.877  118.343 1.00 142.48 ? 233 ARG B CZ  1 
ATOM   3505 N  NH1 . ARG B 1 233 ? 146.275 98.066  119.194 1.00 140.34 ? 233 ARG B NH1 1 
ATOM   3506 N  NH2 . ARG B 1 233 ? 144.860 96.640  118.096 1.00 140.58 ? 233 ARG B NH2 1 
ATOM   3507 N  N   . ALA B 1 234 ? 140.633 102.642 117.961 1.00 134.22 ? 234 ALA B N   1 
ATOM   3508 C  CA  . ALA B 1 234 ? 140.242 103.932 118.516 1.00 132.62 ? 234 ALA B CA  1 
ATOM   3509 C  C   . ALA B 1 234 ? 139.697 103.774 119.928 1.00 135.45 ? 234 ALA B C   1 
ATOM   3510 O  O   . ALA B 1 234 ? 140.031 104.558 120.826 1.00 139.16 ? 234 ALA B O   1 
ATOM   3511 C  CB  . ALA B 1 234 ? 139.209 104.600 117.611 1.00 133.58 ? 234 ALA B CB  1 
ATOM   3512 N  N   . ALA B 1 235 ? 138.864 102.757 120.147 1.00 128.66 ? 235 ALA B N   1 
ATOM   3513 C  CA  . ALA B 1 235 ? 138.368 102.486 121.489 1.00 127.50 ? 235 ALA B CA  1 
ATOM   3514 C  C   . ALA B 1 235 ? 139.511 102.137 122.429 1.00 130.56 ? 235 ALA B C   1 
ATOM   3515 O  O   . ALA B 1 235 ? 139.497 102.519 123.602 1.00 138.67 ? 235 ALA B O   1 
ATOM   3516 C  CB  . ALA B 1 235 ? 137.338 101.360 121.450 1.00 129.26 ? 235 ALA B CB  1 
ATOM   3517 N  N   . PHE B 1 236 ? 140.515 101.417 121.929 1.00 122.87 ? 236 PHE B N   1 
ATOM   3518 C  CA  . PHE B 1 236 ? 141.651 101.031 122.758 1.00 119.29 ? 236 PHE B CA  1 
ATOM   3519 C  C   . PHE B 1 236 ? 142.432 102.251 123.230 1.00 120.07 ? 236 PHE B C   1 
ATOM   3520 O  O   . PHE B 1 236 ? 142.760 102.373 124.416 1.00 127.67 ? 236 PHE B O   1 
ATOM   3521 C  CB  . PHE B 1 236 ? 142.554 100.079 121.976 1.00 121.94 ? 236 PHE B CB  1 
ATOM   3522 C  CG  . PHE B 1 236 ? 143.693 99.527  122.777 1.00 123.79 ? 236 PHE B CG  1 
ATOM   3523 C  CD1 . PHE B 1 236 ? 143.496 98.468  123.641 1.00 122.85 ? 236 PHE B CD1 1 
ATOM   3524 C  CD2 . PHE B 1 236 ? 144.962 100.060 122.657 1.00 124.46 ? 236 PHE B CD2 1 
ATOM   3525 C  CE1 . PHE B 1 236 ? 144.543 97.955  124.375 1.00 122.92 ? 236 PHE B CE1 1 
ATOM   3526 C  CE2 . PHE B 1 236 ? 146.012 99.552  123.389 1.00 121.98 ? 236 PHE B CE2 1 
ATOM   3527 C  CZ  . PHE B 1 236 ? 145.802 98.498  124.249 1.00 121.64 ? 236 PHE B CZ  1 
ATOM   3528 N  N   . VAL B 1 237 ? 142.739 103.173 122.315 1.00 120.11 ? 237 VAL B N   1 
ATOM   3529 C  CA  . VAL B 1 237 ? 143.500 104.354 122.720 1.00 126.68 ? 237 VAL B CA  1 
ATOM   3530 C  C   . VAL B 1 237 ? 142.656 105.258 123.618 1.00 128.07 ? 237 VAL B C   1 
ATOM   3531 O  O   . VAL B 1 237 ? 143.165 105.857 124.579 1.00 129.47 ? 237 VAL B O   1 
ATOM   3532 C  CB  . VAL B 1 237 ? 144.050 105.105 121.493 1.00 126.28 ? 237 VAL B CB  1 
ATOM   3533 C  CG1 . VAL B 1 237 ? 145.134 104.284 120.821 1.00 125.18 ? 237 VAL B CG1 1 
ATOM   3534 C  CG2 . VAL B 1 237 ? 142.950 105.433 120.510 1.00 127.38 ? 237 VAL B CG2 1 
ATOM   3535 N  N   . HIS B 1 238 ? 141.353 105.361 123.336 1.00 127.01 ? 238 HIS B N   1 
ATOM   3536 C  CA  . HIS B 1 238 ? 140.480 106.137 124.208 1.00 124.45 ? 238 HIS B CA  1 
ATOM   3537 C  C   . HIS B 1 238 ? 140.444 105.549 125.611 1.00 126.78 ? 238 HIS B C   1 
ATOM   3538 O  O   . HIS B 1 238 ? 140.467 106.286 126.603 1.00 131.57 ? 238 HIS B O   1 
ATOM   3539 C  CB  . HIS B 1 238 ? 139.073 106.198 123.619 1.00 123.52 ? 238 HIS B CB  1 
ATOM   3540 C  CG  . HIS B 1 238 ? 138.177 107.180 124.301 1.00 123.81 ? 238 HIS B CG  1 
ATOM   3541 N  ND1 . HIS B 1 238 ? 137.916 108.430 123.785 1.00 130.43 ? 238 HIS B ND1 1 
ATOM   3542 C  CD2 . HIS B 1 238 ? 137.481 107.098 125.458 1.00 126.26 ? 238 HIS B CD2 1 
ATOM   3543 C  CE1 . HIS B 1 238 ? 137.097 109.076 124.595 1.00 130.20 ? 238 HIS B CE1 1 
ATOM   3544 N  NE2 . HIS B 1 238 ? 136.817 108.289 125.617 1.00 131.68 ? 238 HIS B NE2 1 
ATOM   3545 N  N   . VAL B 1 239 ? 140.386 104.221 125.714 1.00 119.89 ? 239 VAL B N   1 
ATOM   3546 C  CA  . VAL B 1 239 ? 140.382 103.570 127.015 1.00 117.20 ? 239 VAL B CA  1 
ATOM   3547 C  C   . VAL B 1 239 ? 141.718 103.758 127.715 1.00 122.02 ? 239 VAL B C   1 
ATOM   3548 O  O   . VAL B 1 239 ? 141.768 103.873 128.941 1.00 130.01 ? 239 VAL B O   1 
ATOM   3549 C  CB  . VAL B 1 239 ? 140.010 102.085 126.858 1.00 117.60 ? 239 VAL B CB  1 
ATOM   3550 C  CG1 . VAL B 1 239 ? 140.437 101.287 128.070 1.00 119.19 ? 239 VAL B CG1 1 
ATOM   3551 C  CG2 . VAL B 1 239 ? 138.518 101.950 126.645 1.00 120.80 ? 239 VAL B CG2 1 
ATOM   3552 N  N   . LEU B 1 240 ? 142.820 103.800 126.964 1.00 118.72 ? 240 LEU B N   1 
ATOM   3553 C  CA  . LEU B 1 240 ? 144.110 104.091 127.586 1.00 118.08 ? 240 LEU B CA  1 
ATOM   3554 C  C   . LEU B 1 240 ? 144.125 105.487 128.201 1.00 121.34 ? 240 LEU B C   1 
ATOM   3555 O  O   . LEU B 1 240 ? 144.622 105.680 129.319 1.00 124.57 ? 240 LEU B O   1 
ATOM   3556 C  CB  . LEU B 1 240 ? 145.231 103.940 126.562 1.00 117.16 ? 240 LEU B CB  1 
ATOM   3557 C  CG  . LEU B 1 240 ? 145.623 102.502 126.221 1.00 121.92 ? 240 LEU B CG  1 
ATOM   3558 C  CD1 . LEU B 1 240 ? 146.949 102.474 125.486 1.00 125.92 ? 240 LEU B CD1 1 
ATOM   3559 C  CD2 . LEU B 1 240 ? 145.686 101.648 127.474 1.00 115.89 ? 240 LEU B CD2 1 
ATOM   3560 N  N   . GLY B 1 241 ? 143.582 106.475 127.488 1.00 122.75 ? 241 GLY B N   1 
ATOM   3561 C  CA  . GLY B 1 241 ? 143.472 107.807 128.071 1.00 123.74 ? 241 GLY B CA  1 
ATOM   3562 C  C   . GLY B 1 241 ? 142.568 107.840 129.293 1.00 126.54 ? 241 GLY B C   1 
ATOM   3563 O  O   . GLY B 1 241 ? 142.894 108.466 130.312 1.00 129.29 ? 241 GLY B O   1 
ATOM   3564 N  N   . ASP B 1 242 ? 141.415 107.169 129.202 1.00 122.50 ? 242 ASP B N   1 
ATOM   3565 C  CA  . ASP B 1 242 ? 140.532 107.028 130.355 1.00 120.48 ? 242 ASP B CA  1 
ATOM   3566 C  C   . ASP B 1 242 ? 141.277 106.424 131.537 1.00 123.54 ? 242 ASP B C   1 
ATOM   3567 O  O   . ASP B 1 242 ? 141.098 106.852 132.682 1.00 132.37 ? 242 ASP B O   1 
ATOM   3568 C  CB  . ASP B 1 242 ? 139.332 106.148 130.000 1.00 128.48 ? 242 ASP B CB  1 
ATOM   3569 C  CG  . ASP B 1 242 ? 138.306 106.847 129.119 1.00 132.62 ? 242 ASP B CG  1 
ATOM   3570 O  OD1 . ASP B 1 242 ? 138.534 107.988 128.672 1.00 136.03 ? 242 ASP B OD1 1 
ATOM   3571 O  OD2 . ASP B 1 242 ? 137.248 106.231 128.874 1.00 129.88 ? 242 ASP B OD2 1 
ATOM   3572 N  N   . LEU B 1 243 ? 142.117 105.423 131.273 1.00 111.48 ? 243 LEU B N   1 
ATOM   3573 C  CA  . LEU B 1 243 ? 142.853 104.745 132.331 1.00 114.69 ? 243 LEU B CA  1 
ATOM   3574 C  C   . LEU B 1 243 ? 143.886 105.664 132.961 1.00 115.46 ? 243 LEU B C   1 
ATOM   3575 O  O   . LEU B 1 243 ? 144.115 105.607 134.171 1.00 117.47 ? 243 LEU B O   1 
ATOM   3576 C  CB  . LEU B 1 243 ? 143.519 103.489 131.774 1.00 111.98 ? 243 LEU B CB  1 
ATOM   3577 C  CG  . LEU B 1 243 ? 144.447 102.718 132.708 1.00 113.23 ? 243 LEU B CG  1 
ATOM   3578 C  CD1 . LEU B 1 243 ? 143.697 102.266 133.943 1.00 118.36 ? 243 LEU B CD1 1 
ATOM   3579 C  CD2 . LEU B 1 243 ? 145.052 101.532 131.984 1.00 116.57 ? 243 LEU B CD2 1 
ATOM   3580 N  N   . LEU B 1 244 ? 144.528 106.509 132.156 1.00 111.90 ? 244 LEU B N   1 
ATOM   3581 C  CA  . LEU B 1 244 ? 145.456 107.485 132.722 1.00 110.39 ? 244 LEU B CA  1 
ATOM   3582 C  C   . LEU B 1 244 ? 144.735 108.454 133.654 1.00 114.75 ? 244 LEU B C   1 
ATOM   3583 O  O   . LEU B 1 244 ? 145.215 108.749 134.760 1.00 120.93 ? 244 LEU B O   1 
ATOM   3584 C  CB  . LEU B 1 244 ? 146.166 108.242 131.604 1.00 111.76 ? 244 LEU B CB  1 
ATOM   3585 C  CG  . LEU B 1 244 ? 147.583 108.710 131.922 1.00 114.08 ? 244 LEU B CG  1 
ATOM   3586 C  CD1 . LEU B 1 244 ? 148.531 107.526 131.958 1.00 112.09 ? 244 LEU B CD1 1 
ATOM   3587 C  CD2 . LEU B 1 244 ? 148.039 109.738 130.904 1.00 117.30 ? 244 LEU B CD2 1 
ATOM   3588 N  N   . GLN B 1 245 ? 143.571 108.950 133.231 1.00 117.64 ? 245 GLN B N   1 
ATOM   3589 C  CA  . GLN B 1 245 ? 142.802 109.835 134.105 1.00 111.47 ? 245 GLN B CA  1 
ATOM   3590 C  C   . GLN B 1 245 ? 142.372 109.116 135.379 1.00 115.78 ? 245 GLN B C   1 
ATOM   3591 O  O   . GLN B 1 245 ? 142.408 109.692 136.476 1.00 120.04 ? 245 GLN B O   1 
ATOM   3592 C  CB  . GLN B 1 245 ? 141.585 110.384 133.366 1.00 118.04 ? 245 GLN B CB  1 
ATOM   3593 C  CG  . GLN B 1 245 ? 141.112 111.727 133.884 1.00 122.57 ? 245 GLN B CG  1 
ATOM   3594 C  CD  . GLN B 1 245 ? 139.622 111.923 133.710 1.00 122.91 ? 245 GLN B CD  1 
ATOM   3595 O  OE1 . GLN B 1 245 ? 139.010 111.350 132.811 1.00 124.46 ? 245 GLN B OE1 1 
ATOM   3596 N  NE2 . GLN B 1 245 ? 139.029 112.738 134.573 1.00 117.48 ? 245 GLN B NE2 1 
ATOM   3597 N  N   . SER B 1 246 ? 141.957 107.855 135.253 1.00 114.46 ? 246 SER B N   1 
ATOM   3598 C  CA  . SER B 1 246 ? 141.558 107.083 136.423 1.00 109.41 ? 246 SER B CA  1 
ATOM   3599 C  C   . SER B 1 246 ? 142.734 106.860 137.361 1.00 110.56 ? 246 SER B C   1 
ATOM   3600 O  O   . SER B 1 246 ? 142.565 106.836 138.583 1.00 114.14 ? 246 SER B O   1 
ATOM   3601 C  CB  . SER B 1 246 ? 140.956 105.749 135.990 1.00 114.48 ? 246 SER B CB  1 
ATOM   3602 O  OG  . SER B 1 246 ? 139.738 105.947 135.297 1.00 121.49 ? 246 SER B OG  1 
ATOM   3603 N  N   . PHE B 1 247 ? 143.934 106.684 136.809 1.00 110.42 ? 247 PHE B N   1 
ATOM   3604 C  CA  . PHE B 1 247 ? 145.122 106.552 137.644 1.00 108.83 ? 247 PHE B CA  1 
ATOM   3605 C  C   . PHE B 1 247 ? 145.393 107.835 138.413 1.00 109.30 ? 247 PHE B C   1 
ATOM   3606 O  O   . PHE B 1 247 ? 145.771 107.796 139.589 1.00 116.91 ? 247 PHE B O   1 
ATOM   3607 C  CB  . PHE B 1 247 ? 146.328 106.177 136.787 1.00 109.36 ? 247 PHE B CB  1 
ATOM   3608 C  CG  . PHE B 1 247 ? 146.712 104.734 136.888 1.00 114.68 ? 247 PHE B CG  1 
ATOM   3609 C  CD1 . PHE B 1 247 ? 146.910 104.144 138.122 1.00 117.20 ? 247 PHE B CD1 1 
ATOM   3610 C  CD2 . PHE B 1 247 ? 146.868 103.965 135.751 1.00 113.19 ? 247 PHE B CD2 1 
ATOM   3611 C  CE1 . PHE B 1 247 ? 147.260 102.815 138.219 1.00 117.89 ? 247 PHE B CE1 1 
ATOM   3612 C  CE2 . PHE B 1 247 ? 147.218 102.636 135.841 1.00 114.49 ? 247 PHE B CE2 1 
ATOM   3613 C  CZ  . PHE B 1 247 ? 147.415 102.061 137.077 1.00 117.38 ? 247 PHE B CZ  1 
ATOM   3614 N  N   . GLY B 1 248 ? 145.213 108.984 137.762 1.00 101.49 ? 248 GLY B N   1 
ATOM   3615 C  CA  . GLY B 1 248 ? 145.344 110.244 138.480 1.00 104.05 ? 248 GLY B CA  1 
ATOM   3616 C  C   . GLY B 1 248 ? 144.346 110.371 139.618 1.00 107.85 ? 248 GLY B C   1 
ATOM   3617 O  O   . GLY B 1 248 ? 144.701 110.768 140.736 1.00 111.42 ? 248 GLY B O   1 
ATOM   3618 N  N   . VAL B 1 249 ? 143.086 110.018 139.353 1.00 108.06 ? 249 VAL B N   1 
ATOM   3619 C  CA  . VAL B 1 249 ? 142.062 110.075 140.396 1.00 101.51 ? 249 VAL B CA  1 
ATOM   3620 C  C   . VAL B 1 249 ? 142.400 109.117 141.531 1.00 100.28 ? 249 VAL B C   1 
ATOM   3621 O  O   . VAL B 1 249 ? 142.203 109.432 142.711 1.00 102.40 ? 249 VAL B O   1 
ATOM   3622 C  CB  . VAL B 1 249 ? 140.674 109.778 139.801 1.00 104.23 ? 249 VAL B CB  1 
ATOM   3623 C  CG1 . VAL B 1 249 ? 139.628 109.730 140.897 1.00 101.26 ? 249 VAL B CG1 1 
ATOM   3624 C  CG2 . VAL B 1 249 ? 140.308 110.822 138.766 1.00 107.08 ? 249 VAL B CG2 1 
ATOM   3625 N  N   . LEU B 1 250 ? 142.905 107.930 141.195 1.00 104.42 ? 250 LEU B N   1 
ATOM   3626 C  CA  . LEU B 1 250 ? 143.278 106.960 142.218 1.00 102.54 ? 250 LEU B CA  1 
ATOM   3627 C  C   . LEU B 1 250 ? 144.432 107.469 143.069 1.00 107.28 ? 250 LEU B C   1 
ATOM   3628 O  O   . LEU B 1 250 ? 144.455 107.246 144.282 1.00 115.09 ? 250 LEU B O   1 
ATOM   3629 C  CB  . LEU B 1 250 ? 143.638 105.625 141.573 1.00 102.99 ? 250 LEU B CB  1 
ATOM   3630 C  CG  . LEU B 1 250 ? 144.420 104.647 142.449 1.00 99.81  ? 250 LEU B CG  1 
ATOM   3631 C  CD1 . LEU B 1 250 ? 143.548 104.121 143.570 1.00 98.90  ? 250 LEU B CD1 1 
ATOM   3632 C  CD2 . LEU B 1 250 ? 144.971 103.507 141.619 1.00 106.72 ? 250 LEU B CD2 1 
ATOM   3633 N  N   . ALA B 1 251 ? 145.406 108.138 142.452 1.00 106.32 ? 251 ALA B N   1 
ATOM   3634 C  CA  . ALA B 1 251 ? 146.496 108.720 143.230 1.00 103.83 ? 251 ALA B CA  1 
ATOM   3635 C  C   . ALA B 1 251 ? 145.976 109.780 144.191 1.00 107.60 ? 251 ALA B C   1 
ATOM   3636 O  O   . ALA B 1 251 ? 146.383 109.829 145.360 1.00 109.90 ? 251 ALA B O   1 
ATOM   3637 C  CB  . ALA B 1 251 ? 147.551 109.311 142.298 1.00 104.46 ? 251 ALA B CB  1 
ATOM   3638 N  N   . ALA B 1 252 ? 145.063 110.633 143.718 1.00 111.58 ? 252 ALA B N   1 
ATOM   3639 C  CA  . ALA B 1 252 ? 144.476 111.635 144.605 1.00 109.92 ? 252 ALA B CA  1 
ATOM   3640 C  C   . ALA B 1 252 ? 143.731 110.981 145.764 1.00 114.07 ? 252 ALA B C   1 
ATOM   3641 O  O   . ALA B 1 252 ? 143.851 111.414 146.917 1.00 119.00 ? 252 ALA B O   1 
ATOM   3642 C  CB  . ALA B 1 252 ? 143.544 112.553 143.818 1.00 108.91 ? 252 ALA B CB  1 
ATOM   3643 N  N   . SER B 1 253 ? 142.957 109.932 145.475 1.00 116.18 ? 253 SER B N   1 
ATOM   3644 C  CA  . SER B 1 253 ? 142.205 109.247 146.522 1.00 105.17 ? 253 SER B CA  1 
ATOM   3645 C  C   . SER B 1 253 ? 143.131 108.560 147.516 1.00 102.90 ? 253 SER B C   1 
ATOM   3646 O  O   . SER B 1 253 ? 142.849 108.538 148.718 1.00 110.74 ? 253 SER B O   1 
ATOM   3647 C  CB  . SER B 1 253 ? 141.245 108.238 145.901 1.00 105.77 ? 253 SER B CB  1 
ATOM   3648 O  OG  . SER B 1 253 ? 141.958 107.194 145.268 1.00 116.19 ? 253 SER B OG  1 
ATOM   3649 N  N   . ILE B 1 254 ? 144.229 107.979 147.032 1.00 102.36 ? 254 ILE B N   1 
ATOM   3650 C  CA  . ILE B 1 254 ? 145.206 107.362 147.924 1.00 104.25 ? 254 ILE B CA  1 
ATOM   3651 C  C   . ILE B 1 254 ? 145.805 108.407 148.850 1.00 108.12 ? 254 ILE B C   1 
ATOM   3652 O  O   . ILE B 1 254 ? 145.962 108.175 150.055 1.00 108.30 ? 254 ILE B O   1 
ATOM   3653 C  CB  . ILE B 1 254 ? 146.296 106.643 147.108 1.00 104.09 ? 254 ILE B CB  1 
ATOM   3654 C  CG1 . ILE B 1 254 ? 145.768 105.329 146.540 1.00 109.66 ? 254 ILE B CG1 1 
ATOM   3655 C  CG2 . ILE B 1 254 ? 147.520 106.386 147.965 1.00 101.09 ? 254 ILE B CG2 1 
ATOM   3656 C  CD1 . ILE B 1 254 ? 146.848 104.432 145.987 1.00 109.63 ? 254 ILE B CD1 1 
ATOM   3657 N  N   . LEU B 1 255 ? 146.149 109.575 148.305 1.00 114.00 ? 255 LEU B N   1 
ATOM   3658 C  CA  . LEU B 1 255 ? 146.698 110.636 149.143 1.00 110.13 ? 255 LEU B CA  1 
ATOM   3659 C  C   . LEU B 1 255 ? 145.693 111.086 150.194 1.00 112.08 ? 255 LEU B C   1 
ATOM   3660 O  O   . LEU B 1 255 ? 146.051 111.283 151.360 1.00 115.50 ? 255 LEU B O   1 
ATOM   3661 C  CB  . LEU B 1 255 ? 147.133 111.818 148.280 1.00 110.58 ? 255 LEU B CB  1 
ATOM   3662 C  CG  . LEU B 1 255 ? 147.475 113.093 149.047 1.00 113.84 ? 255 LEU B CG  1 
ATOM   3663 C  CD1 . LEU B 1 255 ? 148.672 112.861 149.948 1.00 115.20 ? 255 LEU B CD1 1 
ATOM   3664 C  CD2 . LEU B 1 255 ? 147.739 114.236 148.088 1.00 115.40 ? 255 LEU B CD2 1 
ATOM   3665 N  N   . ILE B 1 256 ? 144.428 111.250 149.803 1.00 112.51 ? 256 ILE B N   1 
ATOM   3666 C  CA  . ILE B 1 256 ? 143.418 111.716 150.750 1.00 109.21 ? 256 ILE B CA  1 
ATOM   3667 C  C   . ILE B 1 256 ? 143.173 110.677 151.838 1.00 110.85 ? 256 ILE B C   1 
ATOM   3668 O  O   . ILE B 1 256 ? 143.027 111.017 153.017 1.00 117.14 ? 256 ILE B O   1 
ATOM   3669 C  CB  . ILE B 1 256 ? 142.117 112.075 150.013 1.00 105.79 ? 256 ILE B CB  1 
ATOM   3670 C  CG1 . ILE B 1 256 ? 142.330 113.292 149.117 1.00 108.96 ? 256 ILE B CG1 1 
ATOM   3671 C  CG2 . ILE B 1 256 ? 141.003 112.346 151.003 1.00 107.86 ? 256 ILE B CG2 1 
ATOM   3672 C  CD1 . ILE B 1 256 ? 141.063 113.801 148.483 1.00 112.14 ? 256 ILE B CD1 1 
ATOM   3673 N  N   . TYR B 1 257 ? 143.121 109.398 151.462 1.00 117.68 ? 257 TYR B N   1 
ATOM   3674 C  CA  . TYR B 1 257 ? 142.758 108.352 152.412 1.00 113.76 ? 257 TYR B CA  1 
ATOM   3675 C  C   . TYR B 1 257 ? 143.772 108.238 153.542 1.00 115.37 ? 257 TYR B C   1 
ATOM   3676 O  O   . TYR B 1 257 ? 143.396 108.118 154.713 1.00 118.45 ? 257 TYR B O   1 
ATOM   3677 C  CB  . TYR B 1 257 ? 142.619 107.018 151.679 1.00 117.38 ? 257 TYR B CB  1 
ATOM   3678 C  CG  . TYR B 1 257 ? 142.464 105.821 152.585 1.00 119.30 ? 257 TYR B CG  1 
ATOM   3679 C  CD1 . TYR B 1 257 ? 141.259 105.558 153.218 1.00 120.16 ? 257 TYR B CD1 1 
ATOM   3680 C  CD2 . TYR B 1 257 ? 143.520 104.949 152.801 1.00 121.09 ? 257 TYR B CD2 1 
ATOM   3681 C  CE1 . TYR B 1 257 ? 141.112 104.465 154.045 1.00 117.96 ? 257 TYR B CE1 1 
ATOM   3682 C  CE2 . TYR B 1 257 ? 143.381 103.853 153.626 1.00 123.03 ? 257 TYR B CE2 1 
ATOM   3683 C  CZ  . TYR B 1 257 ? 142.175 103.617 154.245 1.00 120.67 ? 257 TYR B CZ  1 
ATOM   3684 O  OH  . TYR B 1 257 ? 142.032 102.525 155.068 1.00 119.35 ? 257 TYR B OH  1 
ATOM   3685 N  N   . PHE B 1 258 ? 145.064 108.266 153.214 1.00 116.15 ? 258 PHE B N   1 
ATOM   3686 C  CA  . PHE B 1 258 ? 146.088 108.111 154.241 1.00 116.80 ? 258 PHE B CA  1 
ATOM   3687 C  C   . PHE B 1 258 ? 146.280 109.390 155.046 1.00 122.11 ? 258 PHE B C   1 
ATOM   3688 O  O   . PHE B 1 258 ? 146.537 109.332 156.253 1.00 122.64 ? 258 PHE B O   1 
ATOM   3689 C  CB  . PHE B 1 258 ? 147.406 107.680 153.604 1.00 120.08 ? 258 PHE B CB  1 
ATOM   3690 C  CG  . PHE B 1 258 ? 147.475 106.215 153.302 1.00 124.28 ? 258 PHE B CG  1 
ATOM   3691 C  CD1 . PHE B 1 258 ? 147.680 105.295 154.313 1.00 120.90 ? 258 PHE B CD1 1 
ATOM   3692 C  CD2 . PHE B 1 258 ? 147.326 105.756 152.007 1.00 123.95 ? 258 PHE B CD2 1 
ATOM   3693 C  CE1 . PHE B 1 258 ? 147.740 103.947 154.037 1.00 121.01 ? 258 PHE B CE1 1 
ATOM   3694 C  CE2 . PHE B 1 258 ? 147.386 104.409 151.726 1.00 122.71 ? 258 PHE B CE2 1 
ATOM   3695 C  CZ  . PHE B 1 258 ? 147.594 103.504 152.742 1.00 123.41 ? 258 PHE B CZ  1 
ATOM   3696 N  N   . LYS B 1 259 ? 146.159 110.549 154.399 1.00 126.43 ? 259 LYS B N   1 
ATOM   3697 C  CA  . LYS B 1 259 ? 146.318 111.849 155.049 1.00 123.49 ? 259 LYS B CA  1 
ATOM   3698 C  C   . LYS B 1 259 ? 145.018 112.620 154.878 1.00 121.28 ? 259 LYS B C   1 
ATOM   3699 O  O   . LYS B 1 259 ? 144.844 113.352 153.891 1.00 123.39 ? 259 LYS B O   1 
ATOM   3700 C  CB  . LYS B 1 259 ? 147.497 112.620 154.460 1.00 124.42 ? 259 LYS B CB  1 
ATOM   3701 C  CG  . LYS B 1 259 ? 148.782 111.821 154.377 1.00 123.36 ? 259 LYS B CG  1 
ATOM   3702 C  CD  . LYS B 1 259 ? 149.646 112.045 155.604 1.00 125.94 ? 259 LYS B CD  1 
ATOM   3703 C  CE  . LYS B 1 259 ? 151.039 111.476 155.407 1.00 127.52 ? 259 LYS B CE  1 
ATOM   3704 N  NZ  . LYS B 1 259 ? 151.013 110.002 155.211 1.00 125.51 ? 259 LYS B NZ  1 
ATOM   3705 N  N   . PRO B 1 260 ? 144.077 112.488 155.813 1.00 121.57 ? 260 PRO B N   1 
ATOM   3706 C  CA  . PRO B 1 260 ? 142.780 113.162 155.653 1.00 123.85 ? 260 PRO B CA  1 
ATOM   3707 C  C   . PRO B 1 260 ? 142.876 114.673 155.630 1.00 128.92 ? 260 PRO B C   1 
ATOM   3708 O  O   . PRO B 1 260 ? 141.943 115.329 155.152 1.00 130.11 ? 260 PRO B O   1 
ATOM   3709 C  CB  . PRO B 1 260 ? 141.975 112.674 156.866 1.00 121.58 ? 260 PRO B CB  1 
ATOM   3710 C  CG  . PRO B 1 260 ? 142.689 111.451 157.343 1.00 124.32 ? 260 PRO B CG  1 
ATOM   3711 C  CD  . PRO B 1 260 ? 144.131 111.673 157.035 1.00 123.72 ? 260 PRO B CD  1 
ATOM   3712 N  N   . GLN B 1 261 ? 143.967 115.252 156.135 1.00 131.96 ? 261 GLN B N   1 
ATOM   3713 C  CA  . GLN B 1 261 ? 144.100 116.702 156.151 1.00 129.15 ? 261 GLN B CA  1 
ATOM   3714 C  C   . GLN B 1 261 ? 144.236 117.291 154.754 1.00 132.15 ? 261 GLN B C   1 
ATOM   3715 O  O   . GLN B 1 261 ? 144.020 118.494 154.581 1.00 133.50 ? 261 GLN B O   1 
ATOM   3716 C  CB  . GLN B 1 261 ? 145.301 117.108 157.004 1.00 125.49 ? 261 GLN B CB  1 
ATOM   3717 C  CG  . GLN B 1 261 ? 146.628 117.029 156.279 1.00 130.16 ? 261 GLN B CG  1 
ATOM   3718 C  CD  . GLN B 1 261 ? 147.550 115.986 156.870 1.00 133.52 ? 261 GLN B CD  1 
ATOM   3719 O  OE1 . GLN B 1 261 ? 147.100 115.025 157.492 1.00 133.16 ? 261 GLN B OE1 1 
ATOM   3720 N  NE2 . GLN B 1 261 ? 148.850 116.170 156.679 1.00 131.05 ? 261 GLN B NE2 1 
ATOM   3721 N  N   . TYR B 1 262 ? 144.586 116.481 153.761 1.00 123.50 ? 262 TYR B N   1 
ATOM   3722 C  CA  . TYR B 1 262 ? 144.757 116.966 152.393 1.00 120.27 ? 262 TYR B CA  1 
ATOM   3723 C  C   . TYR B 1 262 ? 143.480 116.811 151.574 1.00 122.57 ? 262 TYR B C   1 
ATOM   3724 O  O   . TYR B 1 262 ? 143.490 116.240 150.487 1.00 127.89 ? 262 TYR B O   1 
ATOM   3725 C  CB  . TYR B 1 262 ? 145.918 116.239 151.728 1.00 119.86 ? 262 TYR B CB  1 
ATOM   3726 C  CG  . TYR B 1 262 ? 147.271 116.605 152.283 1.00 124.72 ? 262 TYR B CG  1 
ATOM   3727 C  CD1 . TYR B 1 262 ? 147.489 117.839 152.875 1.00 125.31 ? 262 TYR B CD1 1 
ATOM   3728 C  CD2 . TYR B 1 262 ? 148.332 115.716 152.215 1.00 126.02 ? 262 TYR B CD2 1 
ATOM   3729 C  CE1 . TYR B 1 262 ? 148.725 118.175 153.383 1.00 126.55 ? 262 TYR B CE1 1 
ATOM   3730 C  CE2 . TYR B 1 262 ? 149.570 116.043 152.720 1.00 125.51 ? 262 TYR B CE2 1 
ATOM   3731 C  CZ  . TYR B 1 262 ? 149.762 117.273 153.303 1.00 127.17 ? 262 TYR B CZ  1 
ATOM   3732 O  OH  . TYR B 1 262 ? 150.997 117.602 153.807 1.00 126.62 ? 262 TYR B OH  1 
ATOM   3733 N  N   . LYS B 1 263 ? 142.363 117.325 152.091 1.00 114.14 ? 263 LYS B N   1 
ATOM   3734 C  CA  . LYS B 1 263 ? 141.118 117.271 151.336 1.00 113.49 ? 263 LYS B CA  1 
ATOM   3735 C  C   . LYS B 1 263 ? 141.177 118.116 150.074 1.00 120.92 ? 263 LYS B C   1 
ATOM   3736 O  O   . LYS B 1 263 ? 140.394 117.881 149.149 1.00 128.52 ? 263 LYS B O   1 
ATOM   3737 C  CB  . LYS B 1 263 ? 139.945 117.737 152.196 1.00 117.83 ? 263 LYS B CB  1 
ATOM   3738 C  CG  . LYS B 1 263 ? 140.078 117.425 153.667 1.00 121.85 ? 263 LYS B CG  1 
ATOM   3739 C  CD  . LYS B 1 263 ? 138.959 118.075 154.463 1.00 125.10 ? 263 LYS B CD  1 
ATOM   3740 C  CE  . LYS B 1 263 ? 138.745 119.519 154.040 1.00 124.21 ? 263 LYS B CE  1 
ATOM   3741 N  NZ  . LYS B 1 263 ? 137.496 120.082 154.616 1.00 125.60 ? 263 LYS B NZ  1 
ATOM   3742 N  N   . ALA B 1 264 ? 142.087 119.087 150.014 1.00 116.96 ? 264 ALA B N   1 
ATOM   3743 C  CA  . ALA B 1 264 ? 142.168 119.982 148.868 1.00 116.32 ? 264 ALA B CA  1 
ATOM   3744 C  C   . ALA B 1 264 ? 142.616 119.277 147.598 1.00 120.52 ? 264 ALA B C   1 
ATOM   3745 O  O   . ALA B 1 264 ? 142.523 119.872 146.519 1.00 126.02 ? 264 ALA B O   1 
ATOM   3746 C  CB  . ALA B 1 264 ? 143.116 121.140 149.176 1.00 116.10 ? 264 ALA B CB  1 
ATOM   3747 N  N   . ALA B 1 265 ? 143.104 118.039 147.693 1.00 112.43 ? 265 ALA B N   1 
ATOM   3748 C  CA  . ALA B 1 265 ? 143.516 117.312 146.501 1.00 111.46 ? 265 ALA B CA  1 
ATOM   3749 C  C   . ALA B 1 265 ? 142.344 116.978 145.592 1.00 110.70 ? 265 ALA B C   1 
ATOM   3750 O  O   . ALA B 1 265 ? 142.554 116.721 144.403 1.00 115.38 ? 265 ALA B O   1 
ATOM   3751 C  CB  . ALA B 1 265 ? 144.250 116.031 146.893 1.00 110.06 ? 265 ALA B CB  1 
ATOM   3752 N  N   . ASP B 1 266 ? 141.125 116.974 146.115 1.00 117.68 ? 266 ASP B N   1 
ATOM   3753 C  CA  . ASP B 1 266 ? 139.957 116.656 145.305 1.00 120.93 ? 266 ASP B CA  1 
ATOM   3754 C  C   . ASP B 1 266 ? 139.551 117.840 144.427 1.00 125.97 ? 266 ASP B C   1 
ATOM   3755 O  O   . ASP B 1 266 ? 139.412 117.666 143.209 1.00 132.07 ? 266 ASP B O   1 
ATOM   3756 C  CB  . ASP B 1 266 ? 138.798 116.200 146.194 1.00 120.48 ? 266 ASP B CB  1 
ATOM   3757 C  CG  . ASP B 1 266 ? 137.563 115.840 145.402 1.00 133.79 ? 266 ASP B CG  1 
ATOM   3758 O  OD1 . ASP B 1 266 ? 137.705 115.373 144.254 1.00 137.29 ? 266 ASP B OD1 1 
ATOM   3759 O  OD2 . ASP B 1 266 ? 136.446 116.027 145.929 1.00 134.25 ? 266 ASP B OD2 1 
ATOM   3760 N  N   . PRO B 1 267 ? 139.335 119.045 144.976 1.00 110.80 ? 267 PRO B N   1 
ATOM   3761 C  CA  . PRO B 1 267 ? 139.032 120.181 144.088 1.00 115.43 ? 267 PRO B CA  1 
ATOM   3762 C  C   . PRO B 1 267 ? 140.150 120.502 143.111 1.00 123.35 ? 267 PRO B C   1 
ATOM   3763 O  O   . PRO B 1 267 ? 139.878 120.907 141.975 1.00 126.59 ? 267 PRO B O   1 
ATOM   3764 C  CB  . PRO B 1 267 ? 138.783 121.333 145.071 1.00 118.04 ? 267 PRO B CB  1 
ATOM   3765 C  CG  . PRO B 1 267 ? 138.445 120.675 146.351 1.00 114.03 ? 267 PRO B CG  1 
ATOM   3766 C  CD  . PRO B 1 267 ? 139.300 119.462 146.389 1.00 112.22 ? 267 PRO B CD  1 
ATOM   3767 N  N   . ILE B 1 268 ? 141.407 120.331 143.521 1.00 111.06 ? 268 ILE B N   1 
ATOM   3768 C  CA  . ILE B 1 268 ? 142.528 120.601 142.624 1.00 107.89 ? 268 ILE B CA  1 
ATOM   3769 C  C   . ILE B 1 268 ? 142.516 119.627 141.452 1.00 113.78 ? 268 ILE B C   1 
ATOM   3770 O  O   . ILE B 1 268 ? 142.700 120.017 140.291 1.00 119.82 ? 268 ILE B O   1 
ATOM   3771 C  CB  . ILE B 1 268 ? 143.856 120.540 143.397 1.00 104.95 ? 268 ILE B CB  1 
ATOM   3772 C  CG1 . ILE B 1 268 ? 143.991 121.753 144.315 1.00 105.91 ? 268 ILE B CG1 1 
ATOM   3773 C  CG2 . ILE B 1 268 ? 145.029 120.459 142.440 1.00 111.27 ? 268 ILE B CG2 1 
ATOM   3774 C  CD1 . ILE B 1 268 ? 145.062 121.601 145.362 1.00 110.66 ? 268 ILE B CD1 1 
ATOM   3775 N  N   . SER B 1 269 ? 142.302 118.343 141.742 1.00 111.19 ? 269 SER B N   1 
ATOM   3776 C  CA  . SER B 1 269 ? 142.205 117.354 140.675 1.00 111.72 ? 269 SER B CA  1 
ATOM   3777 C  C   . SER B 1 269 ? 141.017 117.644 139.772 1.00 117.04 ? 269 SER B C   1 
ATOM   3778 O  O   . SER B 1 269 ? 141.107 117.494 138.547 1.00 124.33 ? 269 SER B O   1 
ATOM   3779 C  CB  . SER B 1 269 ? 142.098 115.951 141.267 1.00 112.63 ? 269 SER B CB  1 
ATOM   3780 O  OG  . SER B 1 269 ? 142.935 115.817 142.398 1.00 120.82 ? 269 SER B OG  1 
ATOM   3781 N  N   . THR B 1 270 ? 139.893 118.059 140.358 1.00 111.82 ? 270 THR B N   1 
ATOM   3782 C  CA  . THR B 1 270 ? 138.735 118.421 139.552 1.00 112.05 ? 270 THR B CA  1 
ATOM   3783 C  C   . THR B 1 270 ? 139.069 119.559 138.601 1.00 122.51 ? 270 THR B C   1 
ATOM   3784 O  O   . THR B 1 270 ? 138.713 119.515 137.419 1.00 130.65 ? 270 THR B O   1 
ATOM   3785 C  CB  . THR B 1 270 ? 137.567 118.808 140.453 1.00 109.72 ? 270 THR B CB  1 
ATOM   3786 O  OG1 . THR B 1 270 ? 137.256 117.719 141.328 1.00 121.15 ? 270 THR B OG1 1 
ATOM   3787 C  CG2 . THR B 1 270 ? 136.345 119.148 139.623 1.00 114.26 ? 270 THR B CG2 1 
ATOM   3788 N  N   . PHE B 1 271 ? 139.768 120.580 139.097 1.00 123.73 ? 271 PHE B N   1 
ATOM   3789 C  CA  . PHE B 1 271 ? 140.158 121.699 138.246 1.00 119.71 ? 271 PHE B CA  1 
ATOM   3790 C  C   . PHE B 1 271 ? 141.063 121.239 137.112 1.00 119.93 ? 271 PHE B C   1 
ATOM   3791 O  O   . PHE B 1 271 ? 140.847 121.590 135.944 1.00 125.56 ? 271 PHE B O   1 
ATOM   3792 C  CB  . PHE B 1 271 ? 140.854 122.769 139.084 1.00 117.53 ? 271 PHE B CB  1 
ATOM   3793 C  CG  . PHE B 1 271 ? 140.029 123.999 139.300 1.00 121.96 ? 271 PHE B CG  1 
ATOM   3794 C  CD1 . PHE B 1 271 ? 139.180 124.094 140.386 1.00 124.18 ? 271 PHE B CD1 1 
ATOM   3795 C  CD2 . PHE B 1 271 ? 140.097 125.058 138.414 1.00 124.26 ? 271 PHE B CD2 1 
ATOM   3796 C  CE1 . PHE B 1 271 ? 138.418 125.222 140.589 1.00 127.82 ? 271 PHE B CE1 1 
ATOM   3797 C  CE2 . PHE B 1 271 ? 139.335 126.189 138.611 1.00 129.13 ? 271 PHE B CE2 1 
ATOM   3798 C  CZ  . PHE B 1 271 ? 138.495 126.271 139.700 1.00 130.45 ? 271 PHE B CZ  1 
ATOM   3799 N  N   . LEU B 1 272 ? 142.085 120.447 137.437 1.00 111.34 ? 272 LEU B N   1 
ATOM   3800 C  CA  . LEU B 1 272 ? 143.031 120.016 136.413 1.00 112.04 ? 272 LEU B CA  1 
ATOM   3801 C  C   . LEU B 1 272 ? 142.332 119.199 135.336 1.00 116.31 ? 272 LEU B C   1 
ATOM   3802 O  O   . LEU B 1 272 ? 142.521 119.432 134.135 1.00 125.43 ? 272 LEU B O   1 
ATOM   3803 C  CB  . LEU B 1 272 ? 144.163 119.211 137.050 1.00 111.50 ? 272 LEU B CB  1 
ATOM   3804 C  CG  . LEU B 1 272 ? 145.065 119.962 138.029 1.00 119.39 ? 272 LEU B CG  1 
ATOM   3805 C  CD1 . LEU B 1 272 ? 146.352 119.193 138.269 1.00 117.56 ? 272 LEU B CD1 1 
ATOM   3806 C  CD2 . LEU B 1 272 ? 145.357 121.363 137.523 1.00 117.73 ? 272 LEU B CD2 1 
ATOM   3807 N  N   . PHE B 1 273 ? 141.490 118.252 135.750 1.00 113.50 ? 273 PHE B N   1 
ATOM   3808 C  CA  . PHE B 1 273 ? 140.827 117.392 134.781 1.00 110.95 ? 273 PHE B CA  1 
ATOM   3809 C  C   . PHE B 1 273 ? 139.772 118.146 133.984 1.00 110.62 ? 273 PHE B C   1 
ATOM   3810 O  O   . PHE B 1 273 ? 139.562 117.844 132.807 1.00 116.97 ? 273 PHE B O   1 
ATOM   3811 C  CB  . PHE B 1 273 ? 140.223 116.186 135.494 1.00 114.52 ? 273 PHE B CB  1 
ATOM   3812 C  CG  . PHE B 1 273 ? 141.248 115.286 136.116 1.00 118.41 ? 273 PHE B CG  1 
ATOM   3813 C  CD1 . PHE B 1 273 ? 142.446 115.039 135.475 1.00 113.32 ? 273 PHE B CD1 1 
ATOM   3814 C  CD2 . PHE B 1 273 ? 141.020 114.700 137.347 1.00 117.01 ? 273 PHE B CD2 1 
ATOM   3815 C  CE1 . PHE B 1 273 ? 143.393 114.217 136.045 1.00 113.75 ? 273 PHE B CE1 1 
ATOM   3816 C  CE2 . PHE B 1 273 ? 141.966 113.881 137.921 1.00 114.67 ? 273 PHE B CE2 1 
ATOM   3817 C  CZ  . PHE B 1 273 ? 143.153 113.638 137.269 1.00 115.73 ? 273 PHE B CZ  1 
ATOM   3818 N  N   . SER B 1 274 ? 139.112 119.138 134.587 1.00 109.52 ? 274 SER B N   1 
ATOM   3819 C  CA  . SER B 1 274 ? 138.150 119.936 133.835 1.00 114.32 ? 274 SER B CA  1 
ATOM   3820 C  C   . SER B 1 274 ? 138.839 120.785 132.774 1.00 116.89 ? 274 SER B C   1 
ATOM   3821 O  O   . SER B 1 274 ? 138.354 120.883 131.639 1.00 123.21 ? 274 SER B O   1 
ATOM   3822 C  CB  . SER B 1 274 ? 137.344 120.813 134.789 1.00 117.57 ? 274 SER B CB  1 
ATOM   3823 O  OG  . SER B 1 274 ? 136.757 120.034 135.815 1.00 121.97 ? 274 SER B OG  1 
ATOM   3824 N  N   . ILE B 1 275 ? 139.967 121.409 133.121 1.00 113.81 ? 275 ILE B N   1 
ATOM   3825 C  CA  . ILE B 1 275 ? 140.732 122.148 132.117 1.00 115.14 ? 275 ILE B CA  1 
ATOM   3826 C  C   . ILE B 1 275 ? 141.198 121.215 131.007 1.00 115.57 ? 275 ILE B C   1 
ATOM   3827 O  O   . ILE B 1 275 ? 141.137 121.562 129.820 1.00 122.75 ? 275 ILE B O   1 
ATOM   3828 C  CB  . ILE B 1 275 ? 141.910 122.909 132.762 1.00 115.59 ? 275 ILE B CB  1 
ATOM   3829 C  CG1 . ILE B 1 275 ? 141.472 124.198 133.485 1.00 116.69 ? 275 ILE B CG1 1 
ATOM   3830 C  CG2 . ILE B 1 275 ? 142.975 123.231 131.729 1.00 115.66 ? 275 ILE B CG2 1 
ATOM   3831 C  CD1 . ILE B 1 275 ? 140.261 124.135 134.376 1.00 119.94 ? 275 ILE B CD1 1 
ATOM   3832 N  N   . CYS B 1 276 ? 141.660 120.016 131.368 1.00 118.36 ? 276 CYS B N   1 
ATOM   3833 C  CA  . CYS B 1 276 ? 142.074 119.059 130.346 1.00 114.02 ? 276 CYS B CA  1 
ATOM   3834 C  C   . CYS B 1 276 ? 140.909 118.684 129.436 1.00 119.70 ? 276 CYS B C   1 
ATOM   3835 O  O   . CYS B 1 276 ? 141.072 118.589 128.214 1.00 126.89 ? 276 CYS B O   1 
ATOM   3836 C  CB  . CYS B 1 276 ? 142.668 117.813 131.002 1.00 118.85 ? 276 CYS B CB  1 
ATOM   3837 S  SG  . CYS B 1 276 ? 144.461 117.863 131.216 1.00 137.37 ? 276 CYS B SG  1 
ATOM   3838 N  N   . ALA B 1 277 ? 139.724 118.475 130.013 1.00 119.87 ? 277 ALA B N   1 
ATOM   3839 C  CA  . ALA B 1 277 ? 138.559 118.115 129.212 1.00 118.05 ? 277 ALA B CA  1 
ATOM   3840 C  C   . ALA B 1 277 ? 138.175 119.231 128.250 1.00 121.09 ? 277 ALA B C   1 
ATOM   3841 O  O   . ALA B 1 277 ? 137.869 118.974 127.080 1.00 128.68 ? 277 ALA B O   1 
ATOM   3842 C  CB  . ALA B 1 277 ? 137.383 117.770 130.124 1.00 116.20 ? 277 ALA B CB  1 
ATOM   3843 N  N   . LEU B 1 278 ? 138.181 120.478 128.725 1.00 116.39 ? 278 LEU B N   1 
ATOM   3844 C  CA  . LEU B 1 278 ? 137.840 121.596 127.849 1.00 117.46 ? 278 LEU B CA  1 
ATOM   3845 C  C   . LEU B 1 278 ? 138.868 121.757 126.733 1.00 116.77 ? 278 LEU B C   1 
ATOM   3846 O  O   . LEU B 1 278 ? 138.509 122.004 125.572 1.00 120.62 ? 278 LEU B O   1 
ATOM   3847 C  CB  . LEU B 1 278 ? 137.721 122.878 128.668 1.00 117.64 ? 278 LEU B CB  1 
ATOM   3848 C  CG  . LEU B 1 278 ? 136.628 122.862 129.738 1.00 118.40 ? 278 LEU B CG  1 
ATOM   3849 C  CD1 . LEU B 1 278 ? 136.533 124.205 130.436 1.00 115.88 ? 278 LEU B CD1 1 
ATOM   3850 C  CD2 . LEU B 1 278 ? 135.292 122.475 129.137 1.00 122.59 ? 278 LEU B CD2 1 
ATOM   3851 N  N   . GLY B 1 279 ? 140.152 121.618 127.063 1.00 120.55 ? 279 GLY B N   1 
ATOM   3852 C  CA  . GLY B 1 279 ? 141.175 121.690 126.036 1.00 122.54 ? 279 GLY B CA  1 
ATOM   3853 C  C   . GLY B 1 279 ? 141.037 120.589 125.004 1.00 124.22 ? 279 GLY B C   1 
ATOM   3854 O  O   . GLY B 1 279 ? 141.287 120.802 123.816 1.00 130.53 ? 279 GLY B O   1 
ATOM   3855 N  N   . SER B 1 280 ? 140.638 119.394 125.443 1.00 127.25 ? 280 SER B N   1 
ATOM   3856 C  CA  . SER B 1 280 ? 140.426 118.302 124.502 1.00 129.61 ? 280 SER B CA  1 
ATOM   3857 C  C   . SER B 1 280 ? 139.193 118.531 123.640 1.00 127.42 ? 280 SER B C   1 
ATOM   3858 O  O   . SER B 1 280 ? 139.167 118.118 122.476 1.00 125.67 ? 280 SER B O   1 
ATOM   3859 C  CB  . SER B 1 280 ? 140.305 116.979 125.252 1.00 130.69 ? 280 SER B CB  1 
ATOM   3860 O  OG  . SER B 1 280 ? 138.965 116.750 125.649 1.00 132.79 ? 280 SER B OG  1 
ATOM   3861 N  N   . THR B 1 281 ? 138.161 119.168 124.190 1.00 118.69 ? 281 THR B N   1 
ATOM   3862 C  CA  . THR B 1 281 ? 136.938 119.391 123.431 1.00 123.00 ? 281 THR B CA  1 
ATOM   3863 C  C   . THR B 1 281 ? 137.018 120.595 122.501 1.00 121.91 ? 281 THR B C   1 
ATOM   3864 O  O   . THR B 1 281 ? 136.157 120.732 121.626 1.00 123.69 ? 281 THR B O   1 
ATOM   3865 C  CB  . THR B 1 281 ? 135.747 119.560 124.378 1.00 125.72 ? 281 THR B CB  1 
ATOM   3866 O  OG1 . THR B 1 281 ? 134.546 119.159 123.710 1.00 135.64 ? 281 THR B OG1 1 
ATOM   3867 C  CG2 . THR B 1 281 ? 135.606 121.003 124.814 1.00 118.18 ? 281 THR B CG2 1 
ATOM   3868 N  N   . ALA B 1 282 ? 138.010 121.468 122.673 1.00 118.61 ? 282 ALA B N   1 
ATOM   3869 C  CA  . ALA B 1 282 ? 138.127 122.629 121.789 1.00 116.25 ? 282 ALA B CA  1 
ATOM   3870 C  C   . ALA B 1 282 ? 138.245 122.275 120.306 1.00 115.07 ? 282 ALA B C   1 
ATOM   3871 O  O   . ALA B 1 282 ? 137.528 122.889 119.494 1.00 122.06 ? 282 ALA B O   1 
ATOM   3872 C  CB  . ALA B 1 282 ? 139.302 123.500 122.242 1.00 116.29 ? 282 ALA B CB  1 
ATOM   3873 N  N   . PRO B 1 283 ? 139.116 121.349 119.874 1.00 115.98 ? 283 PRO B N   1 
ATOM   3874 C  CA  . PRO B 1 283 ? 139.229 121.093 118.424 1.00 116.90 ? 283 PRO B CA  1 
ATOM   3875 C  C   . PRO B 1 283 ? 137.947 120.597 117.776 1.00 116.00 ? 283 PRO B C   1 
ATOM   3876 O  O   . PRO B 1 283 ? 137.631 120.996 116.646 1.00 119.51 ? 283 PRO B O   1 
ATOM   3877 C  CB  . PRO B 1 283 ? 140.340 120.037 118.345 1.00 117.47 ? 283 PRO B CB  1 
ATOM   3878 C  CG  . PRO B 1 283 ? 141.105 120.196 119.598 1.00 119.67 ? 283 PRO B CG  1 
ATOM   3879 C  CD  . PRO B 1 283 ? 140.095 120.553 120.632 1.00 118.65 ? 283 PRO B CD  1 
ATOM   3880 N  N   . THR B 1 284 ? 137.202 119.726 118.457 1.00 116.78 ? 284 THR B N   1 
ATOM   3881 C  CA  . THR B 1 284 ? 135.945 119.246 117.895 1.00 120.26 ? 284 THR B CA  1 
ATOM   3882 C  C   . THR B 1 284 ? 134.947 120.383 117.754 1.00 115.32 ? 284 THR B C   1 
ATOM   3883 O  O   . THR B 1 284 ? 134.207 120.451 116.767 1.00 118.74 ? 284 THR B O   1 
ATOM   3884 C  CB  . THR B 1 284 ? 135.365 118.133 118.763 1.00 120.97 ? 284 THR B CB  1 
ATOM   3885 O  OG1 . THR B 1 284 ? 134.917 118.682 120.008 1.00 120.69 ? 284 THR B OG1 1 
ATOM   3886 C  CG2 . THR B 1 284 ? 136.415 117.071 119.034 1.00 120.02 ? 284 THR B CG2 1 
ATOM   3887 N  N   . LEU B 1 285 ? 134.914 121.287 118.734 1.00 114.59 ? 285 LEU B N   1 
ATOM   3888 C  CA  . LEU B 1 285 ? 134.045 122.453 118.632 1.00 117.91 ? 285 LEU B CA  1 
ATOM   3889 C  C   . LEU B 1 285 ? 134.441 123.324 117.450 1.00 118.45 ? 285 LEU B C   1 
ATOM   3890 O  O   . LEU B 1 285 ? 133.577 123.829 116.726 1.00 121.88 ? 285 LEU B O   1 
ATOM   3891 C  CB  . LEU B 1 285 ? 134.091 123.254 119.931 1.00 118.25 ? 285 LEU B CB  1 
ATOM   3892 C  CG  . LEU B 1 285 ? 133.479 124.655 119.902 1.00 118.44 ? 285 LEU B CG  1 
ATOM   3893 C  CD1 . LEU B 1 285 ? 132.012 124.592 119.517 1.00 118.69 ? 285 LEU B CD1 1 
ATOM   3894 C  CD2 . LEU B 1 285 ? 133.651 125.340 121.244 1.00 121.12 ? 285 LEU B CD2 1 
ATOM   3895 N  N   . ARG B 1 286 ? 135.745 123.507 117.235 1.00 124.76 ? 286 ARG B N   1 
ATOM   3896 C  CA  . ARG B 1 286 ? 136.201 124.297 116.095 1.00 124.05 ? 286 ARG B CA  1 
ATOM   3897 C  C   . ARG B 1 286 ? 135.758 123.669 114.779 1.00 127.33 ? 286 ARG B C   1 
ATOM   3898 O  O   . ARG B 1 286 ? 135.257 124.360 113.882 1.00 131.93 ? 286 ARG B O   1 
ATOM   3899 C  CB  . ARG B 1 286 ? 137.720 124.441 116.138 1.00 124.36 ? 286 ARG B CB  1 
ATOM   3900 C  CG  . ARG B 1 286 ? 138.248 125.660 115.410 1.00 130.10 ? 286 ARG B CG  1 
ATOM   3901 C  CD  . ARG B 1 286 ? 139.489 125.324 114.604 1.00 130.69 ? 286 ARG B CD  1 
ATOM   3902 N  NE  . ARG B 1 286 ? 140.295 124.291 115.244 1.00 133.36 ? 286 ARG B NE  1 
ATOM   3903 C  CZ  . ARG B 1 286 ? 140.651 123.154 114.664 1.00 133.57 ? 286 ARG B CZ  1 
ATOM   3904 N  NH1 . ARG B 1 286 ? 140.285 122.865 113.426 1.00 131.23 ? 286 ARG B NH1 1 
ATOM   3905 N  NH2 . ARG B 1 286 ? 141.394 122.284 115.343 1.00 132.83 ? 286 ARG B NH2 1 
ATOM   3906 N  N   . ASP B 1 287 ? 135.929 122.352 114.650 1.00 124.45 ? 287 ASP B N   1 
ATOM   3907 C  CA  . ASP B 1 287 ? 135.534 121.673 113.418 1.00 120.65 ? 287 ASP B CA  1 
ATOM   3908 C  C   . ASP B 1 287 ? 134.028 121.751 113.197 1.00 119.17 ? 287 ASP B C   1 
ATOM   3909 O  O   . ASP B 1 287 ? 133.565 121.997 112.075 1.00 121.23 ? 287 ASP B O   1 
ATOM   3910 C  CB  . ASP B 1 287 ? 135.994 120.218 113.456 1.00 125.35 ? 287 ASP B CB  1 
ATOM   3911 C  CG  . ASP B 1 287 ? 137.379 120.033 112.877 1.00 133.54 ? 287 ASP B CG  1 
ATOM   3912 O  OD1 . ASP B 1 287 ? 137.966 121.031 112.411 1.00 132.62 ? 287 ASP B OD1 1 
ATOM   3913 O  OD2 . ASP B 1 287 ? 137.884 118.891 112.892 1.00 131.53 ? 287 ASP B OD2 1 
ATOM   3914 N  N   . VAL B 1 288 ? 133.247 121.544 114.259 1.00 114.80 ? 288 VAL B N   1 
ATOM   3915 C  CA  . VAL B 1 288 ? 131.794 121.603 114.144 1.00 108.99 ? 288 VAL B CA  1 
ATOM   3916 C  C   . VAL B 1 288 ? 131.348 123.000 113.741 1.00 111.28 ? 288 VAL B C   1 
ATOM   3917 O  O   . VAL B 1 288 ? 130.460 123.163 112.897 1.00 111.02 ? 288 VAL B O   1 
ATOM   3918 C  CB  . VAL B 1 288 ? 131.141 121.153 115.464 1.00 102.83 ? 288 VAL B CB  1 
ATOM   3919 C  CG1 . VAL B 1 288 ? 129.730 121.694 115.577 1.00 107.84 ? 288 VAL B CG1 1 
ATOM   3920 C  CG2 . VAL B 1 288 ? 131.141 119.641 115.560 1.00 104.03 ? 288 VAL B CG2 1 
ATOM   3921 N  N   . LEU B 1 289 ? 131.949 124.031 114.340 1.00 110.88 ? 289 LEU B N   1 
ATOM   3922 C  CA  . LEU B 1 289 ? 131.598 125.399 113.981 1.00 108.86 ? 289 LEU B CA  1 
ATOM   3923 C  C   . LEU B 1 289 ? 131.947 125.695 112.531 1.00 111.90 ? 289 LEU B C   1 
ATOM   3924 O  O   . LEU B 1 289 ? 131.181 126.360 111.825 1.00 116.25 ? 289 LEU B O   1 
ATOM   3925 C  CB  . LEU B 1 289 ? 132.303 126.384 114.910 1.00 107.52 ? 289 LEU B CB  1 
ATOM   3926 C  CG  . LEU B 1 289 ? 131.668 126.589 116.282 1.00 112.79 ? 289 LEU B CG  1 
ATOM   3927 C  CD1 . LEU B 1 289 ? 132.140 127.897 116.885 1.00 113.71 ? 289 LEU B CD1 1 
ATOM   3928 C  CD2 . LEU B 1 289 ? 130.154 126.554 116.186 1.00 111.35 ? 289 LEU B CD2 1 
ATOM   3929 N  N   . ARG B 1 290 ? 133.103 125.216 112.069 1.00 116.60 ? 290 ARG B N   1 
ATOM   3930 C  CA  . ARG B 1 290 ? 133.473 125.429 110.675 1.00 110.68 ? 290 ARG B CA  1 
ATOM   3931 C  C   . ARG B 1 290 ? 132.476 124.767 109.736 1.00 109.65 ? 290 ARG B C   1 
ATOM   3932 O  O   . ARG B 1 290 ? 132.097 125.346 108.712 1.00 115.25 ? 290 ARG B O   1 
ATOM   3933 C  CB  . ARG B 1 290 ? 134.881 124.902 110.415 1.00 115.37 ? 290 ARG B CB  1 
ATOM   3934 C  CG  . ARG B 1 290 ? 135.235 124.792 108.947 1.00 110.43 ? 290 ARG B CG  1 
ATOM   3935 C  CD  . ARG B 1 290 ? 136.651 125.259 108.698 1.00 112.01 ? 290 ARG B CD  1 
ATOM   3936 N  NE  . ARG B 1 290 ? 136.996 125.240 107.283 1.00 115.24 ? 290 ARG B NE  1 
ATOM   3937 C  CZ  . ARG B 1 290 ? 138.222 125.421 106.814 1.00 119.33 ? 290 ARG B CZ  1 
ATOM   3938 N  NH1 . ARG B 1 290 ? 139.245 125.637 107.621 1.00 118.11 ? 290 ARG B NH1 1 
ATOM   3939 N  NH2 . ARG B 1 290 ? 138.426 125.380 105.501 1.00 121.26 ? 290 ARG B NH2 1 
ATOM   3940 N  N   . ILE B 1 291 ? 132.039 123.551 110.067 1.00 104.33 ? 291 ILE B N   1 
ATOM   3941 C  CA  . ILE B 1 291 ? 131.049 122.875 109.231 1.00 101.45 ? 291 ILE B CA  1 
ATOM   3942 C  C   . ILE B 1 291 ? 129.728 123.634 109.244 1.00 104.74 ? 291 ILE B C   1 
ATOM   3943 O  O   . ILE B 1 291 ? 129.110 123.853 108.196 1.00 105.05 ? 291 ILE B O   1 
ATOM   3944 C  CB  . ILE B 1 291 ? 130.864 121.418 109.689 1.00 102.45 ? 291 ILE B CB  1 
ATOM   3945 C  CG1 . ILE B 1 291 ? 132.009 120.549 109.182 1.00 108.18 ? 291 ILE B CG1 1 
ATOM   3946 C  CG2 . ILE B 1 291 ? 129.544 120.868 109.191 1.00 101.96 ? 291 ILE B CG2 1 
ATOM   3947 C  CD1 . ILE B 1 291 ? 131.869 119.099 109.553 1.00 109.22 ? 291 ILE B CD1 1 
ATOM   3948 N  N   . LEU B 1 292 ? 129.282 124.059 110.427 1.00 102.95 ? 292 LEU B N   1 
ATOM   3949 C  CA  . LEU B 1 292 ? 127.963 124.668 110.554 1.00 99.41  ? 292 LEU B CA  1 
ATOM   3950 C  C   . LEU B 1 292 ? 127.905 126.049 109.919 1.00 102.46 ? 292 LEU B C   1 
ATOM   3951 O  O   . LEU B 1 292 ? 126.856 126.442 109.401 1.00 109.45 ? 292 LEU B O   1 
ATOM   3952 C  CB  . LEU B 1 292 ? 127.562 124.751 112.024 1.00 100.51 ? 292 LEU B CB  1 
ATOM   3953 C  CG  . LEU B 1 292 ? 127.032 123.467 112.659 1.00 105.30 ? 292 LEU B CG  1 
ATOM   3954 C  CD1 . LEU B 1 292 ? 126.488 123.753 114.042 1.00 109.29 ? 292 LEU B CD1 1 
ATOM   3955 C  CD2 . LEU B 1 292 ? 125.968 122.836 111.786 1.00 96.11  ? 292 LEU B CD2 1 
ATOM   3956 N  N   . MET B 1 293 ? 129.004 126.798 109.945 1.00 100.82 ? 293 MET B N   1 
ATOM   3957 C  CA  . MET B 1 293 ? 129.021 128.131 109.360 1.00 97.67  ? 293 MET B CA  1 
ATOM   3958 C  C   . MET B 1 293 ? 129.119 128.110 107.845 1.00 100.10 ? 293 MET B C   1 
ATOM   3959 O  O   . MET B 1 293 ? 129.383 129.157 107.249 1.00 111.40 ? 293 MET B O   1 
ATOM   3960 C  CB  . MET B 1 293 ? 130.178 128.950 109.936 1.00 100.53 ? 293 MET B CB  1 
ATOM   3961 C  CG  . MET B 1 293 ? 129.924 129.468 111.336 1.00 105.38 ? 293 MET B CG  1 
ATOM   3962 S  SD  . MET B 1 293 ? 129.215 131.122 111.368 1.00 115.18 ? 293 MET B SD  1 
ATOM   3963 C  CE  . MET B 1 293 ? 130.198 131.943 110.124 1.00 103.57 ? 293 MET B CE  1 
ATOM   3964 N  N   . GLU B 1 294 ? 128.917 126.952 107.219 1.00 96.94  ? 294 GLU B N   1 
ATOM   3965 C  CA  . GLU B 1 294 ? 128.969 126.815 105.765 1.00 98.71  ? 294 GLU B CA  1 
ATOM   3966 C  C   . GLU B 1 294 ? 130.347 127.176 105.220 1.00 102.60 ? 294 GLU B C   1 
ATOM   3967 O  O   . GLU B 1 294 ? 130.475 127.830 104.184 1.00 104.03 ? 294 GLU B O   1 
ATOM   3968 C  CB  . GLU B 1 294 ? 127.881 127.654 105.095 1.00 104.75 ? 294 GLU B CB  1 
ATOM   3969 C  CG  . GLU B 1 294 ? 127.231 126.985 103.913 1.00 109.84 ? 294 GLU B CG  1 
ATOM   3970 C  CD  . GLU B 1 294 ? 126.112 126.058 104.315 1.00 111.47 ? 294 GLU B CD  1 
ATOM   3971 O  OE1 . GLU B 1 294 ? 125.943 125.813 105.526 1.00 113.67 ? 294 GLU B OE1 1 
ATOM   3972 O  OE2 . GLU B 1 294 ? 125.396 125.578 103.417 1.00 110.38 ? 294 GLU B OE2 1 
ATOM   3973 N  N   . GLY B 1 295 ? 131.389 126.746 105.924 1.00 103.84 ? 295 GLY B N   1 
ATOM   3974 C  CA  . GLY B 1 295 ? 132.743 126.979 105.475 1.00 105.74 ? 295 GLY B CA  1 
ATOM   3975 C  C   . GLY B 1 295 ? 133.271 125.856 104.605 1.00 107.77 ? 295 GLY B C   1 
ATOM   3976 O  O   . GLY B 1 295 ? 132.678 124.787 104.496 1.00 106.92 ? 295 GLY B O   1 
ATOM   3977 N  N   . THR B 1 296 ? 134.412 126.122 103.983 1.00 105.72 ? 296 THR B N   1 
ATOM   3978 C  CA  . THR B 1 296 ? 135.045 125.131 103.130 1.00 100.36 ? 296 THR B CA  1 
ATOM   3979 C  C   . THR B 1 296 ? 135.469 123.924 103.963 1.00 107.36 ? 296 THR B C   1 
ATOM   3980 O  O   . THR B 1 296 ? 135.939 124.088 105.095 1.00 118.38 ? 296 THR B O   1 
ATOM   3981 C  CB  . THR B 1 296 ? 136.259 125.741 102.428 1.00 106.12 ? 296 THR B CB  1 
ATOM   3982 O  OG1 . THR B 1 296 ? 135.870 126.957 101.780 1.00 118.23 ? 296 THR B OG1 1 
ATOM   3983 C  CG2 . THR B 1 296 ? 136.824 124.795 101.393 1.00 115.27 ? 296 THR B CG2 1 
ATOM   3984 N  N   . PRO B 1 297 ? 135.301 122.704 103.453 1.00 109.32 ? 297 PRO B N   1 
ATOM   3985 C  CA  . PRO B 1 297 ? 135.786 121.531 104.186 1.00 109.93 ? 297 PRO B CA  1 
ATOM   3986 C  C   . PRO B 1 297 ? 137.291 121.594 104.398 1.00 116.24 ? 297 PRO B C   1 
ATOM   3987 O  O   . PRO B 1 297 ? 138.031 122.158 103.592 1.00 119.47 ? 297 PRO B O   1 
ATOM   3988 C  CB  . PRO B 1 297 ? 135.394 120.355 103.282 1.00 107.62 ? 297 PRO B CB  1 
ATOM   3989 C  CG  . PRO B 1 297 ? 135.011 120.959 101.976 1.00 107.28 ? 297 PRO B CG  1 
ATOM   3990 C  CD  . PRO B 1 297 ? 134.510 122.322 102.275 1.00 110.57 ? 297 PRO B CD  1 
ATOM   3991 N  N   . ARG B 1 298 ? 137.735 121.011 105.514 1.00 126.15 ? 298 ARG B N   1 
ATOM   3992 C  CA  . ARG B 1 298 ? 139.133 121.136 105.917 1.00 124.90 ? 298 ARG B CA  1 
ATOM   3993 C  C   . ARG B 1 298 ? 140.076 120.543 104.879 1.00 125.65 ? 298 ARG B C   1 
ATOM   3994 O  O   . ARG B 1 298 ? 141.102 121.147 104.545 1.00 125.32 ? 298 ARG B O   1 
ATOM   3995 C  CB  . ARG B 1 298 ? 139.346 120.463 107.271 1.00 124.97 ? 298 ARG B CB  1 
ATOM   3996 C  CG  . ARG B 1 298 ? 138.687 121.183 108.429 1.00 126.81 ? 298 ARG B CG  1 
ATOM   3997 C  CD  . ARG B 1 298 ? 139.640 122.183 109.059 1.00 130.45 ? 298 ARG B CD  1 
ATOM   3998 N  NE  . ARG B 1 298 ? 138.963 123.067 110.000 1.00 133.81 ? 298 ARG B NE  1 
ATOM   3999 C  CZ  . ARG B 1 298 ? 139.500 124.164 110.514 1.00 134.77 ? 298 ARG B CZ  1 
ATOM   4000 N  NH1 . ARG B 1 298 ? 140.727 124.545 110.200 1.00 128.58 ? 298 ARG B NH1 1 
ATOM   4001 N  NH2 . ARG B 1 298 ? 138.787 124.900 111.362 1.00 133.27 ? 298 ARG B NH2 1 
ATOM   4002 N  N   . ASN B 1 299 ? 139.752 119.360 104.359 1.00 124.94 ? 299 ASN B N   1 
ATOM   4003 C  CA  . ASN B 1 299 ? 140.657 118.699 103.426 1.00 128.44 ? 299 ASN B CA  1 
ATOM   4004 C  C   . ASN B 1 299 ? 140.634 119.366 102.058 1.00 130.30 ? 299 ASN B C   1 
ATOM   4005 O  O   . ASN B 1 299 ? 141.682 119.531 101.424 1.00 130.66 ? 299 ASN B O   1 
ATOM   4006 C  CB  . ASN B 1 299 ? 140.294 117.221 103.306 1.00 131.40 ? 299 ASN B CB  1 
ATOM   4007 C  CG  . ASN B 1 299 ? 139.692 116.667 104.579 1.00 133.46 ? 299 ASN B CG  1 
ATOM   4008 O  OD1 . ASN B 1 299 ? 138.562 116.180 104.585 1.00 132.51 ? 299 ASN B OD1 1 
ATOM   4009 N  ND2 . ASN B 1 299 ? 140.448 116.734 105.669 1.00 131.38 ? 299 ASN B ND2 1 
ATOM   4010 N  N   . VAL B 1 300 ? 139.456 119.755 101.588 1.00 123.96 ? 300 VAL B N   1 
ATOM   4011 C  CA  . VAL B 1 300 ? 139.311 120.309 100.247 1.00 122.50 ? 300 VAL B CA  1 
ATOM   4012 C  C   . VAL B 1 300 ? 139.744 121.768 100.255 1.00 120.21 ? 300 VAL B C   1 
ATOM   4013 O  O   . VAL B 1 300 ? 139.309 122.555 101.103 1.00 121.89 ? 300 VAL B O   1 
ATOM   4014 C  CB  . VAL B 1 300 ? 137.865 120.161 99.755  1.00 123.84 ? 300 VAL B CB  1 
ATOM   4015 C  CG1 . VAL B 1 300 ? 137.787 120.433 98.272  1.00 120.18 ? 300 VAL B CG1 1 
ATOM   4016 C  CG2 . VAL B 1 300 ? 137.346 118.771 100.070 1.00 122.23 ? 300 VAL B CG2 1 
ATOM   4017 N  N   . GLY B 1 301 ? 140.603 122.131 99.310  1.00 106.16 ? 301 GLY B N   1 
ATOM   4018 C  CA  . GLY B 1 301 ? 141.100 123.486 99.194  1.00 108.19 ? 301 GLY B CA  1 
ATOM   4019 C  C   . GLY B 1 301 ? 140.423 124.247 98.070  1.00 112.91 ? 301 GLY B C   1 
ATOM   4020 O  O   . GLY B 1 301 ? 140.056 123.677 97.049  1.00 119.89 ? 301 GLY B O   1 
ATOM   4021 N  N   . PHE B 1 302 ? 140.264 125.555 98.276  1.00 105.11 ? 302 PHE B N   1 
ATOM   4022 C  CA  . PHE B 1 302 ? 139.628 126.399 97.270  1.00 96.90  ? 302 PHE B CA  1 
ATOM   4023 C  C   . PHE B 1 302 ? 140.458 126.454 95.994  1.00 100.64 ? 302 PHE B C   1 
ATOM   4024 O  O   . PHE B 1 302 ? 139.936 126.265 94.889  1.00 115.16 ? 302 PHE B O   1 
ATOM   4025 C  CB  . PHE B 1 302 ? 139.419 127.801 97.840  1.00 106.66 ? 302 PHE B CB  1 
ATOM   4026 C  CG  . PHE B 1 302 ? 138.631 128.714 96.949  1.00 107.43 ? 302 PHE B CG  1 
ATOM   4027 C  CD1 . PHE B 1 302 ? 139.263 129.476 95.983  1.00 105.34 ? 302 PHE B CD1 1 
ATOM   4028 C  CD2 . PHE B 1 302 ? 137.263 128.828 97.091  1.00 106.14 ? 302 PHE B CD2 1 
ATOM   4029 C  CE1 . PHE B 1 302 ? 138.544 130.318 95.170  1.00 100.55 ? 302 PHE B CE1 1 
ATOM   4030 C  CE2 . PHE B 1 302 ? 136.541 129.671 96.280  1.00 107.34 ? 302 PHE B CE2 1 
ATOM   4031 C  CZ  . PHE B 1 302 ? 137.182 130.416 95.320  1.00 106.63 ? 302 PHE B CZ  1 
ATOM   4032 N  N   . GLU B 1 303 ? 141.754 126.724 96.129  1.00 111.70 ? 303 GLU B N   1 
ATOM   4033 C  CA  . GLU B 1 303 ? 142.619 126.848 94.957  1.00 113.35 ? 303 GLU B CA  1 
ATOM   4034 C  C   . GLU B 1 303 ? 142.743 125.556 94.159  1.00 121.47 ? 303 GLU B C   1 
ATOM   4035 O  O   . GLU B 1 303 ? 142.707 125.625 92.919  1.00 121.35 ? 303 GLU B O   1 
ATOM   4036 C  CB  . GLU B 1 303 ? 143.991 127.372 95.386  1.00 118.14 ? 303 GLU B CB  1 
ATOM   4037 C  CG  . GLU B 1 303 ? 143.997 128.841 95.738  1.00 123.07 ? 303 GLU B CG  1 
ATOM   4038 C  CD  . GLU B 1 303 ? 143.757 129.077 97.213  1.00 131.54 ? 303 GLU B CD  1 
ATOM   4039 O  OE1 . GLU B 1 303 ? 143.411 128.108 97.922  1.00 129.99 ? 303 GLU B OE1 1 
ATOM   4040 O  OE2 . GLU B 1 303 ? 143.917 130.229 97.666  1.00 128.87 ? 303 GLU B OE2 1 
ATOM   4041 N  N   . PRO B 1 304 ? 142.941 124.377 94.765  1.00 118.80 ? 304 PRO B N   1 
ATOM   4042 C  CA  . PRO B 1 304 ? 142.966 123.155 93.944  1.00 110.89 ? 304 PRO B CA  1 
ATOM   4043 C  C   . PRO B 1 304 ? 141.691 122.933 93.153  1.00 114.43 ? 304 PRO B C   1 
ATOM   4044 O  O   . PRO B 1 304 ? 141.757 122.555 91.978  1.00 119.89 ? 304 PRO B O   1 
ATOM   4045 C  CB  . PRO B 1 304 ? 143.190 122.047 94.979  1.00 110.40 ? 304 PRO B CB  1 
ATOM   4046 C  CG  . PRO B 1 304 ? 143.881 122.716 96.094  1.00 113.90 ? 304 PRO B CG  1 
ATOM   4047 C  CD  . PRO B 1 304 ? 143.293 124.087 96.167  1.00 116.51 ? 304 PRO B CD  1 
ATOM   4048 N  N   . VAL B 1 305 ? 140.529 123.185 93.755  1.00 102.97 ? 305 VAL B N   1 
ATOM   4049 C  CA  . VAL B 1 305 ? 139.272 123.000 93.039  1.00 98.66  ? 305 VAL B CA  1 
ATOM   4050 C  C   . VAL B 1 305 ? 139.144 124.013 91.911  1.00 101.91 ? 305 VAL B C   1 
ATOM   4051 O  O   . VAL B 1 305 ? 138.715 123.676 90.802  1.00 113.41 ? 305 VAL B O   1 
ATOM   4052 C  CB  . VAL B 1 305 ? 138.083 123.085 94.011  1.00 95.59  ? 305 VAL B CB  1 
ATOM   4053 C  CG1 . VAL B 1 305 ? 136.778 122.956 93.255  1.00 99.71  ? 305 VAL B CG1 1 
ATOM   4054 C  CG2 . VAL B 1 305 ? 138.190 122.008 95.061  1.00 100.58 ? 305 VAL B CG2 1 
ATOM   4055 N  N   . ARG B 1 306 ? 139.506 125.270 92.174  1.00 110.38 ? 306 ARG B N   1 
ATOM   4056 C  CA  . ARG B 1 306 ? 139.421 126.286 91.131  1.00 110.97 ? 306 ARG B CA  1 
ATOM   4057 C  C   . ARG B 1 306 ? 140.353 125.965 89.972  1.00 115.51 ? 306 ARG B C   1 
ATOM   4058 O  O   . ARG B 1 306 ? 139.990 126.149 88.805  1.00 124.63 ? 306 ARG B O   1 
ATOM   4059 C  CB  . ARG B 1 306 ? 139.737 127.664 91.706  1.00 114.38 ? 306 ARG B CB  1 
ATOM   4060 C  CG  . ARG B 1 306 ? 139.496 128.798 90.729  1.00 115.01 ? 306 ARG B CG  1 
ATOM   4061 C  CD  . ARG B 1 306 ? 140.002 130.121 91.269  1.00 114.84 ? 306 ARG B CD  1 
ATOM   4062 N  NE  . ARG B 1 306 ? 141.278 129.977 91.959  1.00 124.98 ? 306 ARG B NE  1 
ATOM   4063 C  CZ  . ARG B 1 306 ? 142.453 129.893 91.352  1.00 126.68 ? 306 ARG B CZ  1 
ATOM   4064 N  NH1 . ARG B 1 306 ? 142.554 129.931 90.034  1.00 121.12 ? 306 ARG B NH1 1 
ATOM   4065 N  NH2 . ARG B 1 306 ? 143.555 129.765 92.085  1.00 122.59 ? 306 ARG B NH2 1 
ATOM   4066 N  N   . ASP B 1 307 ? 141.561 125.485 90.271  1.00 115.42 ? 307 ASP B N   1 
ATOM   4067 C  CA  . ASP B 1 307 ? 142.498 125.137 89.209  1.00 114.60 ? 307 ASP B CA  1 
ATOM   4068 C  C   . ASP B 1 307 ? 142.029 123.913 88.436  1.00 115.67 ? 307 ASP B C   1 
ATOM   4069 O  O   . ASP B 1 307 ? 142.232 123.827 87.220  1.00 118.62 ? 307 ASP B O   1 
ATOM   4070 C  CB  . ASP B 1 307 ? 143.889 124.907 89.792  1.00 118.86 ? 307 ASP B CB  1 
ATOM   4071 C  CG  . ASP B 1 307 ? 144.452 126.147 90.452  1.00 128.54 ? 307 ASP B CG  1 
ATOM   4072 O  OD1 . ASP B 1 307 ? 143.751 127.179 90.469  1.00 129.66 ? 307 ASP B OD1 1 
ATOM   4073 O  OD2 . ASP B 1 307 ? 145.594 126.092 90.952  1.00 125.46 ? 307 ASP B OD2 1 
ATOM   4074 N  N   . THR B 1 308 ? 141.411 122.950 89.123  1.00 108.84 ? 308 THR B N   1 
ATOM   4075 C  CA  . THR B 1 308 ? 140.837 121.805 88.427  1.00 105.79 ? 308 THR B CA  1 
ATOM   4076 C  C   . THR B 1 308 ? 139.731 122.242 87.478  1.00 111.68 ? 308 THR B C   1 
ATOM   4077 O  O   . THR B 1 308 ? 139.663 121.780 86.334  1.00 114.87 ? 308 THR B O   1 
ATOM   4078 C  CB  . THR B 1 308 ? 140.298 120.795 89.438  1.00 103.38 ? 308 THR B CB  1 
ATOM   4079 O  OG1 . THR B 1 308 ? 141.380 120.284 90.224  1.00 115.25 ? 308 THR B OG1 1 
ATOM   4080 C  CG2 . THR B 1 308 ? 139.610 119.648 88.730  1.00 108.66 ? 308 THR B CG2 1 
ATOM   4081 N  N   . LEU B 1 309 ? 138.859 123.142 87.936  1.00 107.70 ? 309 LEU B N   1 
ATOM   4082 C  CA  . LEU B 1 309 ? 137.766 123.605 87.090  1.00 96.73  ? 309 LEU B CA  1 
ATOM   4083 C  C   . LEU B 1 309 ? 138.281 124.418 85.911  1.00 106.42 ? 309 LEU B C   1 
ATOM   4084 O  O   . LEU B 1 309 ? 137.768 124.293 84.795  1.00 118.62 ? 309 LEU B O   1 
ATOM   4085 C  CB  . LEU B 1 309 ? 136.778 124.423 87.915  1.00 94.31  ? 309 LEU B CB  1 
ATOM   4086 C  CG  . LEU B 1 309 ? 135.933 123.604 88.887  1.00 96.47  ? 309 LEU B CG  1 
ATOM   4087 C  CD1 . LEU B 1 309 ? 134.984 124.499 89.653  1.00 104.62 ? 309 LEU B CD1 1 
ATOM   4088 C  CD2 . LEU B 1 309 ? 135.173 122.530 88.140  1.00 96.61  ? 309 LEU B CD2 1 
ATOM   4089 N  N   . LEU B 1 310 ? 139.293 125.256 86.135  1.00 104.14 ? 310 LEU B N   1 
ATOM   4090 C  CA  . LEU B 1 310 ? 139.809 126.091 85.059  1.00 104.07 ? 310 LEU B CA  1 
ATOM   4091 C  C   . LEU B 1 310 ? 140.651 125.306 84.066  1.00 109.07 ? 310 LEU B C   1 
ATOM   4092 O  O   . LEU B 1 310 ? 140.881 125.787 82.953  1.00 110.60 ? 310 LEU B O   1 
ATOM   4093 C  CB  . LEU B 1 310 ? 140.628 127.242 85.637  1.00 104.31 ? 310 LEU B CB  1 
ATOM   4094 C  CG  . LEU B 1 310 ? 139.820 128.446 86.115  1.00 106.67 ? 310 LEU B CG  1 
ATOM   4095 C  CD1 . LEU B 1 310 ? 140.568 129.187 87.202  1.00 111.80 ? 310 LEU B CD1 1 
ATOM   4096 C  CD2 . LEU B 1 310 ? 139.513 129.368 84.954  1.00 107.65 ? 310 LEU B CD2 1 
ATOM   4097 N  N   . SER B 1 311 ? 141.113 124.114 84.438  1.00 115.97 ? 311 SER B N   1 
ATOM   4098 C  CA  . SER B 1 311 ? 141.919 123.298 83.541  1.00 117.38 ? 311 SER B CA  1 
ATOM   4099 C  C   . SER B 1 311 ? 141.086 122.522 82.532  1.00 119.43 ? 311 SER B C   1 
ATOM   4100 O  O   . SER B 1 311 ? 141.657 121.932 81.610  1.00 118.07 ? 311 SER B O   1 
ATOM   4101 C  CB  . SER B 1 311 ? 142.776 122.322 84.347  1.00 115.65 ? 311 SER B CB  1 
ATOM   4102 O  OG  . SER B 1 311 ? 141.962 121.428 85.083  1.00 122.07 ? 311 SER B OG  1 
ATOM   4103 N  N   . VAL B 1 312 ? 139.770 122.503 82.686  1.00 118.49 ? 312 VAL B N   1 
ATOM   4104 C  CA  . VAL B 1 312 ? 138.908 121.800 81.730  1.00 112.57 ? 312 VAL B CA  1 
ATOM   4105 C  C   . VAL B 1 312 ? 138.979 122.508 80.383  1.00 116.54 ? 312 VAL B C   1 
ATOM   4106 O  O   . VAL B 1 312 ? 138.815 123.739 80.326  1.00 119.71 ? 312 VAL B O   1 
ATOM   4107 C  CB  . VAL B 1 312 ? 137.472 121.750 82.250  1.00 107.73 ? 312 VAL B CB  1 
ATOM   4108 C  CG1 . VAL B 1 312 ? 136.561 121.102 81.227  1.00 109.73 ? 312 VAL B CG1 1 
ATOM   4109 C  CG2 . VAL B 1 312 ? 137.416 121.003 83.567  1.00 110.36 ? 312 VAL B CG2 1 
ATOM   4110 N  N   . PRO B 1 313 ? 139.225 121.796 79.285  1.00 121.77 ? 313 PRO B N   1 
ATOM   4111 C  CA  . PRO B 1 313 ? 139.323 122.466 77.982  1.00 123.52 ? 313 PRO B CA  1 
ATOM   4112 C  C   . PRO B 1 313 ? 138.012 123.110 77.564  1.00 127.05 ? 313 PRO B C   1 
ATOM   4113 O  O   . PRO B 1 313 ? 137.026 122.419 77.294  1.00 126.16 ? 313 PRO B O   1 
ATOM   4114 C  CB  . PRO B 1 313 ? 139.722 121.330 77.031  1.00 117.13 ? 313 PRO B CB  1 
ATOM   4115 C  CG  . PRO B 1 313 ? 139.295 120.084 77.723  1.00 120.15 ? 313 PRO B CG  1 
ATOM   4116 C  CD  . PRO B 1 313 ? 139.456 120.347 79.185  1.00 118.63 ? 313 PRO B CD  1 
ATOM   4117 N  N   . GLY B 1 314 ? 137.996 124.444 77.505  1.00 124.26 ? 314 GLY B N   1 
ATOM   4118 C  CA  . GLY B 1 314 ? 136.812 125.213 77.163  1.00 119.54 ? 314 GLY B CA  1 
ATOM   4119 C  C   . GLY B 1 314 ? 136.428 126.233 78.216  1.00 120.02 ? 314 GLY B C   1 
ATOM   4120 O  O   . GLY B 1 314 ? 135.862 127.278 77.881  1.00 123.84 ? 314 GLY B O   1 
ATOM   4121 N  N   . VAL B 1 315 ? 136.728 125.951 79.483  1.00 106.33 ? 315 VAL B N   1 
ATOM   4122 C  CA  . VAL B 1 315 ? 136.384 126.872 80.558  1.00 107.36 ? 315 VAL B CA  1 
ATOM   4123 C  C   . VAL B 1 315 ? 137.314 128.076 80.510  1.00 113.30 ? 315 VAL B C   1 
ATOM   4124 O  O   . VAL B 1 315 ? 138.541 127.932 80.446  1.00 118.47 ? 315 VAL B O   1 
ATOM   4125 C  CB  . VAL B 1 315 ? 136.459 126.164 81.918  1.00 104.80 ? 315 VAL B CB  1 
ATOM   4126 C  CG1 . VAL B 1 315 ? 136.120 127.129 83.033  1.00 105.83 ? 315 VAL B CG1 1 
ATOM   4127 C  CG2 . VAL B 1 315 ? 135.524 124.978 81.942  1.00 109.16 ? 315 VAL B CG2 1 
ATOM   4128 N  N   . ARG B 1 316 ? 136.731 129.272 80.541  1.00 122.58 ? 316 ARG B N   1 
ATOM   4129 C  CA  . ARG B 1 316 ? 137.493 130.514 80.491  1.00 118.01 ? 316 ARG B CA  1 
ATOM   4130 C  C   . ARG B 1 316 ? 137.613 131.199 81.843  1.00 121.10 ? 316 ARG B C   1 
ATOM   4131 O  O   . ARG B 1 316 ? 138.654 131.792 82.137  1.00 130.41 ? 316 ARG B O   1 
ATOM   4132 C  CB  . ARG B 1 316 ? 136.859 131.484 79.493  1.00 117.49 ? 316 ARG B CB  1 
ATOM   4133 C  CG  . ARG B 1 316 ? 137.371 131.333 78.079  1.00 122.07 ? 316 ARG B CG  1 
ATOM   4134 C  CD  . ARG B 1 316 ? 138.727 131.992 77.926  1.00 122.19 ? 316 ARG B CD  1 
ATOM   4135 N  NE  . ARG B 1 316 ? 138.611 133.410 77.613  1.00 127.84 ? 316 ARG B NE  1 
ATOM   4136 C  CZ  . ARG B 1 316 ? 138.678 133.913 76.388  1.00 129.39 ? 316 ARG B CZ  1 
ATOM   4137 N  NH1 . ARG B 1 316 ? 138.857 133.138 75.332  1.00 126.64 ? 316 ARG B NH1 1 
ATOM   4138 N  NH2 . ARG B 1 316 ? 138.563 135.227 76.220  1.00 127.37 ? 316 ARG B NH2 1 
ATOM   4139 N  N   . ALA B 1 317 ? 136.577 131.140 82.672  1.00 107.37 ? 317 ALA B N   1 
ATOM   4140 C  CA  . ALA B 1 317 ? 136.595 131.807 83.964  1.00 111.70 ? 317 ALA B CA  1 
ATOM   4141 C  C   . ALA B 1 317 ? 135.719 131.019 84.928  1.00 111.19 ? 317 ALA B C   1 
ATOM   4142 O  O   . ALA B 1 317 ? 135.171 129.970 84.582  1.00 115.41 ? 317 ALA B O   1 
ATOM   4143 C  CB  . ALA B 1 317 ? 136.139 133.263 83.826  1.00 113.49 ? 317 ALA B CB  1 
ATOM   4144 N  N   . THR B 1 318 ? 135.589 131.530 86.148  1.00 107.17 ? 318 THR B N   1 
ATOM   4145 C  CA  . THR B 1 318 ? 134.810 130.869 87.183  1.00 107.16 ? 318 THR B CA  1 
ATOM   4146 C  C   . THR B 1 318 ? 134.372 131.913 88.196  1.00 113.73 ? 318 THR B C   1 
ATOM   4147 O  O   . THR B 1 318 ? 135.148 132.796 88.568  1.00 119.40 ? 318 THR B O   1 
ATOM   4148 C  CB  . THR B 1 318 ? 135.617 129.764 87.876  1.00 111.09 ? 318 THR B CB  1 
ATOM   4149 O  OG1 . THR B 1 318 ? 136.060 128.809 86.906  1.00 119.55 ? 318 THR B OG1 1 
ATOM   4150 C  CG2 . THR B 1 318 ? 134.777 129.055 88.920  1.00 112.66 ? 318 THR B CG2 1 
ATOM   4151 N  N   . HIS B 1 319 ? 133.122 131.807 88.633  1.00 112.44 ? 319 HIS B N   1 
ATOM   4152 C  CA  . HIS B 1 319 ? 132.611 132.684 89.674  1.00 109.17 ? 319 HIS B CA  1 
ATOM   4153 C  C   . HIS B 1 319 ? 131.585 131.917 90.490  1.00 107.30 ? 319 HIS B C   1 
ATOM   4154 O  O   . HIS B 1 319 ? 131.064 130.887 90.060  1.00 116.25 ? 319 HIS B O   1 
ATOM   4155 C  CB  . HIS B 1 319 ? 132.015 133.971 89.094  1.00 113.00 ? 319 HIS B CB  1 
ATOM   4156 C  CG  . HIS B 1 319 ? 131.023 133.747 87.996  1.00 111.92 ? 319 HIS B CG  1 
ATOM   4157 N  ND1 . HIS B 1 319 ? 129.664 133.865 88.186  1.00 117.56 ? 319 HIS B ND1 1 
ATOM   4158 C  CD2 . HIS B 1 319 ? 131.195 133.447 86.687  1.00 109.94 ? 319 HIS B CD2 1 
ATOM   4159 C  CE1 . HIS B 1 319 ? 129.039 133.630 87.046  1.00 123.20 ? 319 HIS B CE1 1 
ATOM   4160 N  NE2 . HIS B 1 319 ? 129.946 133.372 86.121  1.00 119.05 ? 319 HIS B NE2 1 
ATOM   4161 N  N   . GLU B 1 320 ? 131.315 132.432 91.687  1.00 110.85 ? 320 GLU B N   1 
ATOM   4162 C  CA  . GLU B 1 320 ? 130.344 131.837 92.603  1.00 112.29 ? 320 GLU B CA  1 
ATOM   4163 C  C   . GLU B 1 320 ? 130.686 130.383 92.908  1.00 113.16 ? 320 GLU B C   1 
ATOM   4164 O  O   . GLU B 1 320 ? 129.814 129.515 92.961  1.00 120.86 ? 320 GLU B O   1 
ATOM   4165 C  CB  . GLU B 1 320 ? 128.926 131.958 92.051  1.00 115.93 ? 320 GLU B CB  1 
ATOM   4166 C  CG  . GLU B 1 320 ? 128.482 133.382 91.815  1.00 122.59 ? 320 GLU B CG  1 
ATOM   4167 C  CD  . GLU B 1 320 ? 127.015 133.584 92.113  1.00 129.73 ? 320 GLU B CD  1 
ATOM   4168 O  OE1 . GLU B 1 320 ? 126.501 132.922 93.038  1.00 125.41 ? 320 GLU B OE1 1 
ATOM   4169 O  OE2 . GLU B 1 320 ? 126.375 134.402 91.421  1.00 133.12 ? 320 GLU B OE2 1 
ATOM   4170 N  N   . LEU B 1 321 ? 131.971 130.114 93.112  1.00 90.64  ? 321 LEU B N   1 
ATOM   4171 C  CA  . LEU B 1 321 ? 132.424 128.780 93.485  1.00 90.59  ? 321 LEU B CA  1 
ATOM   4172 C  C   . LEU B 1 321 ? 132.176 128.584 94.974  1.00 89.09  ? 321 LEU B C   1 
ATOM   4173 O  O   . LEU B 1 321 ? 132.802 129.245 95.806  1.00 102.31 ? 321 LEU B O   1 
ATOM   4174 C  CB  . LEU B 1 321 ? 133.898 128.602 93.140  1.00 92.05  ? 321 LEU B CB  1 
ATOM   4175 C  CG  . LEU B 1 321 ? 134.612 127.394 93.743  1.00 91.57  ? 321 LEU B CG  1 
ATOM   4176 C  CD1 . LEU B 1 321 ? 134.007 126.108 93.228  1.00 97.03  ? 321 LEU B CD1 1 
ATOM   4177 C  CD2 . LEU B 1 321 ? 136.089 127.445 93.422  1.00 90.42  ? 321 LEU B CD2 1 
ATOM   4178 N  N   . HIS B 1 322 ? 131.258 127.685 95.314  1.00 85.22  ? 322 HIS B N   1 
ATOM   4179 C  CA  . HIS B 1 322 ? 130.881 127.424 96.694  1.00 86.64  ? 322 HIS B CA  1 
ATOM   4180 C  C   . HIS B 1 322 ? 131.269 126.003 97.064  1.00 92.18  ? 322 HIS B C   1 
ATOM   4181 O  O   . HIS B 1 322 ? 130.913 125.056 96.359  1.00 102.15 ? 322 HIS B O   1 
ATOM   4182 C  CB  . HIS B 1 322 ? 129.381 127.624 96.905  1.00 92.88  ? 322 HIS B CB  1 
ATOM   4183 C  CG  . HIS B 1 322 ? 128.932 129.041 96.743  1.00 97.39  ? 322 HIS B CG  1 
ATOM   4184 N  ND1 . HIS B 1 322 ? 129.481 130.081 97.458  1.00 99.84  ? 322 HIS B ND1 1 
ATOM   4185 C  CD2 . HIS B 1 322 ? 127.985 129.589 95.948  1.00 99.23  ? 322 HIS B CD2 1 
ATOM   4186 C  CE1 . HIS B 1 322 ? 128.892 131.210 97.110  1.00 105.94 ? 322 HIS B CE1 1 
ATOM   4187 N  NE2 . HIS B 1 322 ? 127.980 130.939 96.195  1.00 108.59 ? 322 HIS B NE2 1 
ATOM   4188 N  N   . LEU B 1 323 ? 131.999 125.860 98.166  1.00 90.52  ? 323 LEU B N   1 
ATOM   4189 C  CA  . LEU B 1 323 ? 132.372 124.561 98.702  1.00 85.17  ? 323 LEU B CA  1 
ATOM   4190 C  C   . LEU B 1 323 ? 131.971 124.507 100.164 1.00 87.78  ? 323 LEU B C   1 
ATOM   4191 O  O   . LEU B 1 323 ? 132.344 125.388 100.944 1.00 101.99 ? 323 LEU B O   1 
ATOM   4192 C  CB  . LEU B 1 323 ? 133.873 124.308 98.562  1.00 84.47  ? 323 LEU B CB  1 
ATOM   4193 C  CG  . LEU B 1 323 ? 134.484 124.541 97.184  1.00 91.96  ? 323 LEU B CG  1 
ATOM   4194 C  CD1 . LEU B 1 323 ? 135.993 124.569 97.280  1.00 94.06  ? 323 LEU B CD1 1 
ATOM   4195 C  CD2 . LEU B 1 323 ? 134.031 123.467 96.220  1.00 97.09  ? 323 LEU B CD2 1 
ATOM   4196 N  N   . TRP B 1 324 ? 131.209 123.483 100.533 1.00 74.80  ? 324 TRP B N   1 
ATOM   4197 C  CA  . TRP B 1 324 ? 130.818 123.297 101.920 1.00 82.07  ? 324 TRP B CA  1 
ATOM   4198 C  C   . TRP B 1 324 ? 130.515 121.827 102.147 1.00 89.32  ? 324 TRP B C   1 
ATOM   4199 O  O   . TRP B 1 324 ? 130.358 121.052 101.203 1.00 98.48  ? 324 TRP B O   1 
ATOM   4200 C  CB  . TRP B 1 324 ? 129.621 124.177 102.299 1.00 88.32  ? 324 TRP B CB  1 
ATOM   4201 C  CG  . TRP B 1 324 ? 128.308 123.720 101.757 1.00 87.24  ? 324 TRP B CG  1 
ATOM   4202 C  CD1 . TRP B 1 324 ? 127.317 123.088 102.441 1.00 89.72  ? 324 TRP B CD1 1 
ATOM   4203 C  CD2 . TRP B 1 324 ? 127.832 123.880 100.418 1.00 84.57  ? 324 TRP B CD2 1 
ATOM   4204 N  NE1 . TRP B 1 324 ? 126.255 122.835 101.612 1.00 89.16  ? 324 TRP B NE1 1 
ATOM   4205 C  CE2 . TRP B 1 324 ? 126.547 123.313 100.363 1.00 86.46  ? 324 TRP B CE2 1 
ATOM   4206 C  CE3 . TRP B 1 324 ? 128.368 124.444 99.260  1.00 91.20  ? 324 TRP B CE3 1 
ATOM   4207 C  CZ2 . TRP B 1 324 ? 125.793 123.293 99.198  1.00 94.61  ? 324 TRP B CZ2 1 
ATOM   4208 C  CZ3 . TRP B 1 324 ? 127.619 124.422 98.106  1.00 86.49  ? 324 TRP B CZ3 1 
ATOM   4209 C  CH2 . TRP B 1 324 ? 126.347 123.850 98.081  1.00 93.05  ? 324 TRP B CH2 1 
ATOM   4210 N  N   . ALA B 1 325 ? 130.446 121.449 103.418 1.00 92.49  ? 325 ALA B N   1 
ATOM   4211 C  CA  . ALA B 1 325 ? 130.310 120.058 103.814 1.00 91.74  ? 325 ALA B CA  1 
ATOM   4212 C  C   . ALA B 1 325 ? 129.093 119.885 104.706 1.00 97.51  ? 325 ALA B C   1 
ATOM   4213 O  O   . ALA B 1 325 ? 128.906 120.646 105.660 1.00 103.51 ? 325 ALA B O   1 
ATOM   4214 C  CB  . ALA B 1 325 ? 131.565 119.577 104.543 1.00 97.15  ? 325 ALA B CB  1 
ATOM   4215 N  N   . LEU B 1 326 ? 128.263 118.891 104.389 1.00 96.97  ? 326 LEU B N   1 
ATOM   4216 C  CA  . LEU B 1 326 ? 127.203 118.504 105.312 1.00 94.51  ? 326 LEU B CA  1 
ATOM   4217 C  C   . LEU B 1 326 ? 127.783 117.893 106.578 1.00 99.80  ? 326 LEU B C   1 
ATOM   4218 O  O   . LEU B 1 326 ? 127.304 118.164 107.683 1.00 110.49 ? 326 LEU B O   1 
ATOM   4219 C  CB  . LEU B 1 326 ? 126.246 117.527 104.637 1.00 98.40  ? 326 LEU B CB  1 
ATOM   4220 C  CG  . LEU B 1 326 ? 125.318 118.099 103.568 1.00 101.38 ? 326 LEU B CG  1 
ATOM   4221 C  CD1 . LEU B 1 326 ? 124.211 117.114 103.273 1.00 103.77 ? 326 LEU B CD1 1 
ATOM   4222 C  CD2 . LEU B 1 326 ? 124.746 119.429 104.008 1.00 101.00 ? 326 LEU B CD2 1 
ATOM   4223 N  N   . THR B 1 327 ? 128.812 117.064 106.436 1.00 107.19 ? 327 THR B N   1 
ATOM   4224 C  CA  . THR B 1 327 ? 129.507 116.488 107.576 1.00 107.51 ? 327 THR B CA  1 
ATOM   4225 C  C   . THR B 1 327 ? 130.970 116.305 107.191 1.00 110.69 ? 327 THR B C   1 
ATOM   4226 O  O   . THR B 1 327 ? 131.423 116.804 106.158 1.00 121.03 ? 327 THR B O   1 
ATOM   4227 C  CB  . THR B 1 327 ? 128.849 115.175 108.013 1.00 107.15 ? 327 THR B CB  1 
ATOM   4228 O  OG1 . THR B 1 327 ? 129.590 114.613 109.101 1.00 116.56 ? 327 THR B OG1 1 
ATOM   4229 C  CG2 . THR B 1 327 ? 128.817 114.186 106.867 1.00 106.89 ? 327 THR B CG2 1 
ATOM   4230 N  N   . LEU B 1 328 ? 131.715 115.583 108.028 1.00 113.71 ? 328 LEU B N   1 
ATOM   4231 C  CA  . LEU B 1 328 ? 133.138 115.391 107.779 1.00 117.42 ? 328 LEU B CA  1 
ATOM   4232 C  C   . LEU B 1 328 ? 133.412 114.588 106.515 1.00 117.89 ? 328 LEU B C   1 
ATOM   4233 O  O   . LEU B 1 328 ? 134.521 114.664 105.980 1.00 122.12 ? 328 LEU B O   1 
ATOM   4234 C  CB  . LEU B 1 328 ? 133.791 114.700 108.973 1.00 121.28 ? 328 LEU B CB  1 
ATOM   4235 C  CG  . LEU B 1 328 ? 133.638 115.390 110.325 1.00 123.12 ? 328 LEU B CG  1 
ATOM   4236 C  CD1 . LEU B 1 328 ? 134.048 114.445 111.433 1.00 124.25 ? 328 LEU B CD1 1 
ATOM   4237 C  CD2 . LEU B 1 328 ? 134.474 116.654 110.370 1.00 115.72 ? 328 LEU B CD2 1 
ATOM   4238 N  N   . THR B 1 329 ? 132.438 113.820 106.031 1.00 114.21 ? 329 THR B N   1 
ATOM   4239 C  CA  . THR B 1 329 ? 132.628 112.988 104.854 1.00 119.21 ? 329 THR B CA  1 
ATOM   4240 C  C   . THR B 1 329 ? 131.735 113.361 103.681 1.00 124.14 ? 329 THR B C   1 
ATOM   4241 O  O   . THR B 1 329 ? 131.986 112.889 102.567 1.00 123.83 ? 329 THR B O   1 
ATOM   4242 C  CB  . THR B 1 329 ? 132.392 111.510 105.200 1.00 126.59 ? 329 THR B CB  1 
ATOM   4243 O  OG1 . THR B 1 329 ? 130.988 111.231 105.174 1.00 132.19 ? 329 THR B OG1 1 
ATOM   4244 C  CG2 . THR B 1 329 ? 132.937 111.192 106.581 1.00 119.34 ? 329 THR B CG2 1 
ATOM   4245 N  N   . TYR B 1 330 ? 130.711 114.183 103.889 1.00 109.83 ? 330 TYR B N   1 
ATOM   4246 C  CA  . TYR B 1 330 ? 129.783 114.575 102.835 1.00 102.54 ? 330 TYR B CA  1 
ATOM   4247 C  C   . TYR B 1 330 ? 130.116 115.998 102.403 1.00 101.24 ? 330 TYR B C   1 
ATOM   4248 O  O   . TYR B 1 330 ? 129.907 116.947 103.162 1.00 106.48 ? 330 TYR B O   1 
ATOM   4249 C  CB  . TYR B 1 330 ? 128.342 114.473 103.326 1.00 101.98 ? 330 TYR B CB  1 
ATOM   4250 C  CG  . TYR B 1 330 ? 127.312 114.336 102.233 1.00 100.97 ? 330 TYR B CG  1 
ATOM   4251 C  CD1 . TYR B 1 330 ? 126.874 115.443 101.524 1.00 103.23 ? 330 TYR B CD1 1 
ATOM   4252 C  CD2 . TYR B 1 330 ? 126.766 113.103 101.920 1.00 100.03 ? 330 TYR B CD2 1 
ATOM   4253 C  CE1 . TYR B 1 330 ? 125.929 115.324 100.531 1.00 106.79 ? 330 TYR B CE1 1 
ATOM   4254 C  CE2 . TYR B 1 330 ? 125.820 112.975 100.928 1.00 99.98  ? 330 TYR B CE2 1 
ATOM   4255 C  CZ  . TYR B 1 330 ? 125.405 114.089 100.237 1.00 106.10 ? 330 TYR B CZ  1 
ATOM   4256 O  OH  . TYR B 1 330 ? 124.462 113.966 99.245  1.00 111.41 ? 330 TYR B OH  1 
ATOM   4257 N  N   . HIS B 1 331 ? 130.626 116.144 101.184 1.00 98.70  ? 331 HIS B N   1 
ATOM   4258 C  CA  . HIS B 1 331 ? 131.044 117.432 100.654 1.00 97.08  ? 331 HIS B CA  1 
ATOM   4259 C  C   . HIS B 1 331 ? 130.177 117.810 99.463  1.00 102.13 ? 331 HIS B C   1 
ATOM   4260 O  O   . HIS B 1 331 ? 129.851 116.962 98.628  1.00 104.04 ? 331 HIS B O   1 
ATOM   4261 C  CB  . HIS B 1 331 ? 132.512 117.405 100.232 1.00 99.69  ? 331 HIS B CB  1 
ATOM   4262 C  CG  . HIS B 1 331 ? 133.449 117.004 101.326 1.00 102.77 ? 331 HIS B CG  1 
ATOM   4263 N  ND1 . HIS B 1 331 ? 133.234 117.331 102.647 1.00 104.56 ? 331 HIS B ND1 1 
ATOM   4264 C  CD2 . HIS B 1 331 ? 134.606 116.304 101.296 1.00 101.43 ? 331 HIS B CD2 1 
ATOM   4265 C  CE1 . HIS B 1 331 ? 134.218 116.849 103.383 1.00 104.28 ? 331 HIS B CE1 1 
ATOM   4266 N  NE2 . HIS B 1 331 ? 135.064 116.221 102.588 1.00 107.80 ? 331 HIS B NE2 1 
ATOM   4267 N  N   . VAL B 1 332 ? 129.810 119.086 99.389  1.00 89.57  ? 332 VAL B N   1 
ATOM   4268 C  CA  . VAL B 1 332 ? 129.003 119.616 98.299  1.00 85.73  ? 332 VAL B CA  1 
ATOM   4269 C  C   . VAL B 1 332 ? 129.801 120.698 97.590  1.00 83.88  ? 332 VAL B C   1 
ATOM   4270 O  O   . VAL B 1 332 ? 130.650 121.361 98.191  1.00 99.27  ? 332 VAL B O   1 
ATOM   4271 C  CB  . VAL B 1 332 ? 127.655 120.175 98.802  1.00 93.79  ? 332 VAL B CB  1 
ATOM   4272 C  CG1 . VAL B 1 332 ? 126.644 120.212 97.676  1.00 96.46  ? 332 VAL B CG1 1 
ATOM   4273 C  CG2 . VAL B 1 332 ? 127.135 119.348 99.959  1.00 91.47  ? 332 VAL B CG2 1 
ATOM   4274 N  N   . ALA B 1 333 ? 129.527 120.873 96.300  1.00 86.25  ? 333 ALA B N   1 
ATOM   4275 C  CA  . ALA B 1 333 ? 130.228 121.874 95.513  1.00 90.98  ? 333 ALA B CA  1 
ATOM   4276 C  C   . ALA B 1 333 ? 129.269 122.501 94.514  1.00 99.59  ? 333 ALA B C   1 
ATOM   4277 O  O   . ALA B 1 333 ? 128.334 121.860 94.032  1.00 104.70 ? 333 ALA B O   1 
ATOM   4278 C  CB  . ALA B 1 333 ? 131.432 121.273 94.783  1.00 95.95  ? 333 ALA B CB  1 
ATOM   4279 N  N   . SER B 1 334 ? 129.518 123.771 94.209  1.00 98.86  ? 334 SER B N   1 
ATOM   4280 C  CA  . SER B 1 334 ? 128.773 124.490 93.186  1.00 89.68  ? 334 SER B CA  1 
ATOM   4281 C  C   . SER B 1 334 ? 129.698 125.528 92.576  1.00 94.13  ? 334 SER B C   1 
ATOM   4282 O  O   . SER B 1 334 ? 130.623 126.017 93.226  1.00 109.63 ? 334 SER B O   1 
ATOM   4283 C  CB  . SER B 1 334 ? 127.517 125.150 93.757  1.00 95.21  ? 334 SER B CB  1 
ATOM   4284 O  OG  . SER B 1 334 ? 126.729 124.219 94.472  1.00 109.36 ? 334 SER B OG  1 
ATOM   4285 N  N   . ALA B 1 335 ? 129.436 125.865 91.318  1.00 86.73  ? 335 ALA B N   1 
ATOM   4286 C  CA  . ALA B 1 335 ? 130.256 126.845 90.623  1.00 87.95  ? 335 ALA B CA  1 
ATOM   4287 C  C   . ALA B 1 335 ? 129.540 127.270 89.353  1.00 100.31 ? 335 ALA B C   1 
ATOM   4288 O  O   . ALA B 1 335 ? 128.659 126.569 88.851  1.00 113.55 ? 335 ALA B O   1 
ATOM   4289 C  CB  . ALA B 1 335 ? 131.641 126.293 90.284  1.00 92.59  ? 335 ALA B CB  1 
ATOM   4290 N  N   . HIS B 1 336 ? 129.934 128.432 88.841  1.00 100.79 ? 336 HIS B N   1 
ATOM   4291 C  CA  . HIS B 1 336 ? 129.504 128.915 87.537  1.00 96.00  ? 336 HIS B CA  1 
ATOM   4292 C  C   . HIS B 1 336 ? 130.710 128.881 86.616  1.00 99.60  ? 336 HIS B C   1 
ATOM   4293 O  O   . HIS B 1 336 ? 131.739 129.490 86.920  1.00 112.29 ? 336 HIS B O   1 
ATOM   4294 C  CB  . HIS B 1 336 ? 128.948 130.335 87.620  1.00 104.80 ? 336 HIS B CB  1 
ATOM   4295 C  CG  . HIS B 1 336 ? 127.710 130.464 88.448  1.00 102.46 ? 336 HIS B CG  1 
ATOM   4296 N  ND1 . HIS B 1 336 ? 126.755 131.426 88.204  1.00 105.06 ? 336 HIS B ND1 1 
ATOM   4297 C  CD2 . HIS B 1 336 ? 127.275 129.766 89.522  1.00 103.86 ? 336 HIS B CD2 1 
ATOM   4298 C  CE1 . HIS B 1 336 ? 125.781 131.310 89.087  1.00 101.54 ? 336 HIS B CE1 1 
ATOM   4299 N  NE2 . HIS B 1 336 ? 126.072 130.310 89.899  1.00 101.19 ? 336 HIS B NE2 1 
ATOM   4300 N  N   . LEU B 1 337 ? 130.590 128.176 85.500  1.00 97.79  ? 337 LEU B N   1 
ATOM   4301 C  CA  . LEU B 1 337 ? 131.679 128.043 84.544  1.00 98.40  ? 337 LEU B CA  1 
ATOM   4302 C  C   . LEU B 1 337 ? 131.362 128.882 83.317  1.00 101.56 ? 337 LEU B C   1 
ATOM   4303 O  O   . LEU B 1 337 ? 130.358 128.640 82.640  1.00 114.99 ? 337 LEU B O   1 
ATOM   4304 C  CB  . LEU B 1 337 ? 131.893 126.583 84.153  1.00 102.28 ? 337 LEU B CB  1 
ATOM   4305 C  CG  . LEU B 1 337 ? 132.047 125.585 85.298  1.00 104.25 ? 337 LEU B CG  1 
ATOM   4306 C  CD1 . LEU B 1 337 ? 132.350 124.207 84.751  1.00 102.38 ? 337 LEU B CD1 1 
ATOM   4307 C  CD2 . LEU B 1 337 ? 133.134 126.034 86.248  1.00 108.97 ? 337 LEU B CD2 1 
ATOM   4308 N  N   . ALA B 1 338 ? 132.212 129.860 83.034  1.00 101.48 ? 338 ALA B N   1 
ATOM   4309 C  CA  . ALA B 1 338 ? 132.089 130.685 81.840  1.00 102.40 ? 338 ALA B CA  1 
ATOM   4310 C  C   . ALA B 1 338 ? 132.942 130.052 80.750  1.00 106.71 ? 338 ALA B C   1 
ATOM   4311 O  O   . ALA B 1 338 ? 134.171 130.154 80.777  1.00 122.97 ? 338 ALA B O   1 
ATOM   4312 C  CB  . ALA B 1 338 ? 132.523 132.121 82.119  1.00 109.05 ? 338 ALA B CB  1 
ATOM   4313 N  N   . ILE B 1 339 ? 132.292 129.401 79.795  1.00 109.91 ? 339 ILE B N   1 
ATOM   4314 C  CA  . ILE B 1 339 ? 132.984 128.641 78.773  1.00 113.88 ? 339 ILE B CA  1 
ATOM   4315 C  C   . ILE B 1 339 ? 133.125 129.491 77.520  1.00 117.34 ? 339 ILE B C   1 
ATOM   4316 O  O   . ILE B 1 339 ? 132.452 130.507 77.340  1.00 122.77 ? 339 ILE B O   1 
ATOM   4317 C  CB  . ILE B 1 339 ? 132.260 127.316 78.460  1.00 109.54 ? 339 ILE B CB  1 
ATOM   4318 C  CG1 . ILE B 1 339 ? 130.951 127.589 77.723  1.00 112.61 ? 339 ILE B CG1 1 
ATOM   4319 C  CG2 . ILE B 1 339 ? 132.003 126.543 79.735  1.00 112.70 ? 339 ILE B CG2 1 
ATOM   4320 C  CD1 . ILE B 1 339 ? 130.363 126.373 77.059  1.00 117.57 ? 339 ILE B CD1 1 
ATOM   4321 N  N   . ASP B 1 340 ? 134.021 129.064 76.637  1.00 133.38 ? 340 ASP B N   1 
ATOM   4322 C  CA  . ASP B 1 340 ? 134.228 129.759 75.380  1.00 132.07 ? 340 ASP B CA  1 
ATOM   4323 C  C   . ASP B 1 340 ? 133.032 129.560 74.456  1.00 134.30 ? 340 ASP B C   1 
ATOM   4324 O  O   . ASP B 1 340 ? 132.241 128.626 74.608  1.00 138.08 ? 340 ASP B O   1 
ATOM   4325 C  CB  . ASP B 1 340 ? 135.503 129.266 74.698  1.00 132.72 ? 340 ASP B CB  1 
ATOM   4326 C  CG  . ASP B 1 340 ? 136.633 130.269 74.783  1.00 138.97 ? 340 ASP B CG  1 
ATOM   4327 O  OD1 . ASP B 1 340 ? 136.356 131.484 74.709  1.00 138.60 ? 340 ASP B OD1 1 
ATOM   4328 O  OD2 . ASP B 1 340 ? 137.798 129.843 74.926  1.00 139.46 ? 340 ASP B OD2 1 
ATOM   4329 N  N   . SER B 1 341 ? 132.905 130.465 73.484  1.00 135.18 ? 341 SER B N   1 
ATOM   4330 C  CA  . SER B 1 341 ? 131.812 130.365 72.524  1.00 135.74 ? 341 SER B CA  1 
ATOM   4331 C  C   . SER B 1 341 ? 131.913 129.085 71.706  1.00 136.10 ? 341 SER B C   1 
ATOM   4332 O  O   . SER B 1 341 ? 130.901 128.424 71.446  1.00 135.22 ? 341 SER B O   1 
ATOM   4333 C  CB  . SER B 1 341 ? 131.805 131.588 71.609  1.00 135.73 ? 341 SER B CB  1 
ATOM   4334 O  OG  . SER B 1 341 ? 132.853 131.514 70.660  1.00 136.87 ? 341 SER B OG  1 
ATOM   4335 N  N   . THR B 1 342 ? 133.123 128.718 71.293  1.00 143.25 ? 342 THR B N   1 
ATOM   4336 C  CA  . THR B 1 342 ? 133.338 127.498 70.516  1.00 144.54 ? 342 THR B CA  1 
ATOM   4337 C  C   . THR B 1 342 ? 133.645 126.319 71.442  1.00 143.81 ? 342 THR B C   1 
ATOM   4338 O  O   . THR B 1 342 ? 134.695 125.683 71.369  1.00 144.71 ? 342 THR B O   1 
ATOM   4339 C  CB  . THR B 1 342 ? 134.453 127.709 69.501  1.00 146.08 ? 342 THR B CB  1 
ATOM   4340 O  OG1 . THR B 1 342 ? 135.720 127.467 70.126  1.00 148.57 ? 342 THR B OG1 1 
ATOM   4341 C  CG2 . THR B 1 342 ? 134.422 129.131 68.966  1.00 144.49 ? 342 THR B CG2 1 
ATOM   4342 N  N   . ALA B 1 343 ? 132.692 126.034 72.324  1.00 139.17 ? 343 ALA B N   1 
ATOM   4343 C  CA  . ALA B 1 343 ? 132.807 124.926 73.257  1.00 139.62 ? 343 ALA B CA  1 
ATOM   4344 C  C   . ALA B 1 343 ? 131.466 124.215 73.351  1.00 142.43 ? 343 ALA B C   1 
ATOM   4345 O  O   . ALA B 1 343 ? 130.413 124.790 73.069  1.00 143.80 ? 343 ALA B O   1 
ATOM   4346 C  CB  . ALA B 1 343 ? 133.262 125.394 74.644  1.00 138.10 ? 343 ALA B CB  1 
ATOM   4347 N  N   . ASP B 1 344 ? 131.518 122.947 73.751  1.00 141.04 ? 344 ASP B N   1 
ATOM   4348 C  CA  . ASP B 1 344 ? 130.316 122.138 73.862  1.00 139.31 ? 344 ASP B CA  1 
ATOM   4349 C  C   . ASP B 1 344 ? 129.942 122.084 75.333  1.00 139.36 ? 344 ASP B C   1 
ATOM   4350 O  O   . ASP B 1 344 ? 130.701 121.518 76.133  1.00 140.16 ? 344 ASP B O   1 
ATOM   4351 C  CB  . ASP B 1 344 ? 130.569 120.734 73.295  1.00 139.08 ? 344 ASP B CB  1 
ATOM   4352 C  CG  . ASP B 1 344 ? 129.501 119.702 73.673  1.00 143.71 ? 344 ASP B CG  1 
ATOM   4353 O  OD1 . ASP B 1 344 ? 129.239 118.829 72.822  1.00 144.31 ? 344 ASP B OD1 1 
ATOM   4354 O  OD2 . ASP B 1 344 ? 128.947 119.703 74.789  1.00 143.68 ? 344 ASP B OD2 1 
ATOM   4355 N  N   . PRO B 1 345 ? 128.811 122.665 75.742  1.00 123.32 ? 345 PRO B N   1 
ATOM   4356 C  CA  . PRO B 1 345 ? 128.473 122.674 77.174  1.00 122.80 ? 345 PRO B CA  1 
ATOM   4357 C  C   . PRO B 1 345 ? 128.342 121.289 77.782  1.00 122.88 ? 345 PRO B C   1 
ATOM   4358 O  O   . PRO B 1 345 ? 128.715 121.094 78.945  1.00 126.50 ? 345 PRO B O   1 
ATOM   4359 C  CB  . PRO B 1 345 ? 127.143 123.438 77.210  1.00 121.31 ? 345 PRO B CB  1 
ATOM   4360 C  CG  . PRO B 1 345 ? 127.114 124.228 75.948  1.00 119.49 ? 345 PRO B CG  1 
ATOM   4361 C  CD  . PRO B 1 345 ? 127.821 123.393 74.933  1.00 119.59 ? 345 PRO B CD  1 
ATOM   4362 N  N   . GLU B 1 346 ? 127.820 120.317 77.032  1.00 132.68 ? 346 GLU B N   1 
ATOM   4363 C  CA  . GLU B 1 346 ? 127.653 118.975 77.581  1.00 134.31 ? 346 GLU B CA  1 
ATOM   4364 C  C   . GLU B 1 346 ? 129.001 118.329 77.873  1.00 133.65 ? 346 GLU B C   1 
ATOM   4365 O  O   . GLU B 1 346 ? 129.196 117.730 78.937  1.00 132.23 ? 346 GLU B O   1 
ATOM   4366 C  CB  . GLU B 1 346 ? 126.840 118.111 76.617  1.00 133.30 ? 346 GLU B CB  1 
ATOM   4367 C  CG  . GLU B 1 346 ? 125.369 118.471 76.560  1.00 138.64 ? 346 GLU B CG  1 
ATOM   4368 C  CD  . GLU B 1 346 ? 124.794 118.770 77.927  1.00 142.66 ? 346 GLU B CD  1 
ATOM   4369 O  OE1 . GLU B 1 346 ? 124.750 117.847 78.767  1.00 138.97 ? 346 GLU B OE1 1 
ATOM   4370 O  OE2 . GLU B 1 346 ? 124.390 119.929 78.162  1.00 139.46 ? 346 GLU B OE2 1 
ATOM   4371 N  N   . ALA B 1 347 ? 129.945 118.440 76.935  1.00 124.64 ? 347 ALA B N   1 
ATOM   4372 C  CA  . ALA B 1 347 ? 131.266 117.858 77.144  1.00 120.95 ? 347 ALA B CA  1 
ATOM   4373 C  C   . ALA B 1 347 ? 131.987 118.529 78.304  1.00 123.17 ? 347 ALA B C   1 
ATOM   4374 O  O   . ALA B 1 347 ? 132.613 117.855 79.130  1.00 126.53 ? 347 ALA B O   1 
ATOM   4375 C  CB  . ALA B 1 347 ? 132.094 117.965 75.865  1.00 117.45 ? 347 ALA B CB  1 
ATOM   4376 N  N   . VAL B 1 348 ? 131.906 119.858 78.383  1.00 111.49 ? 348 VAL B N   1 
ATOM   4377 C  CA  . VAL B 1 348 ? 132.542 120.583 79.479  1.00 107.90 ? 348 VAL B CA  1 
ATOM   4378 C  C   . VAL B 1 348 ? 131.949 120.150 80.811  1.00 109.88 ? 348 VAL B C   1 
ATOM   4379 O  O   . VAL B 1 348 ? 132.672 119.894 81.780  1.00 115.83 ? 348 VAL B O   1 
ATOM   4380 C  CB  . VAL B 1 348 ? 132.401 122.101 79.269  1.00 105.76 ? 348 VAL B CB  1 
ATOM   4381 C  CG1 . VAL B 1 348 ? 132.718 122.844 80.549  1.00 107.18 ? 348 VAL B CG1 1 
ATOM   4382 C  CG2 . VAL B 1 348 ? 133.302 122.564 78.144  1.00 115.09 ? 348 VAL B CG2 1 
ATOM   4383 N  N   . LEU B 1 349 ? 130.621 120.053 80.873  1.00 111.36 ? 349 LEU B N   1 
ATOM   4384 C  CA  . LEU B 1 349 ? 129.960 119.661 82.112  1.00 108.89 ? 349 LEU B CA  1 
ATOM   4385 C  C   . LEU B 1 349 ? 130.357 118.251 82.526  1.00 111.49 ? 349 LEU B C   1 
ATOM   4386 O  O   . LEU B 1 349 ? 130.668 118.000 83.696  1.00 116.91 ? 349 LEU B O   1 
ATOM   4387 C  CB  . LEU B 1 349 ? 128.447 119.769 81.939  1.00 107.36 ? 349 LEU B CB  1 
ATOM   4388 C  CG  . LEU B 1 349 ? 127.586 119.355 83.126  1.00 113.67 ? 349 LEU B CG  1 
ATOM   4389 C  CD1 . LEU B 1 349 ? 127.961 120.160 84.351  1.00 117.09 ? 349 LEU B CD1 1 
ATOM   4390 C  CD2 . LEU B 1 349 ? 126.125 119.542 82.785  1.00 112.31 ? 349 LEU B CD2 1 
ATOM   4391 N  N   . ALA B 1 350 ? 130.361 117.318 81.573  1.00 111.86 ? 350 ALA B N   1 
ATOM   4392 C  CA  . ALA B 1 350 ? 130.715 115.939 81.890  1.00 114.03 ? 350 ALA B CA  1 
ATOM   4393 C  C   . ALA B 1 350 ? 132.155 115.839 82.371  1.00 118.94 ? 350 ALA B C   1 
ATOM   4394 O  O   . ALA B 1 350 ? 132.443 115.175 83.375  1.00 122.30 ? 350 ALA B O   1 
ATOM   4395 C  CB  . ALA B 1 350 ? 130.492 115.048 80.669  1.00 116.01 ? 350 ALA B CB  1 
ATOM   4396 N  N   . GLU B 1 351 ? 133.077 116.506 81.671  1.00 117.29 ? 351 GLU B N   1 
ATOM   4397 C  CA  . GLU B 1 351 ? 134.481 116.443 82.054  1.00 114.72 ? 351 GLU B CA  1 
ATOM   4398 C  C   . GLU B 1 351 ? 134.712 117.066 83.423  1.00 118.45 ? 351 GLU B C   1 
ATOM   4399 O  O   . GLU B 1 351 ? 135.443 116.510 84.248  1.00 121.23 ? 351 GLU B O   1 
ATOM   4400 C  CB  . GLU B 1 351 ? 135.341 117.131 80.997  1.00 114.01 ? 351 GLU B CB  1 
ATOM   4401 C  CG  . GLU B 1 351 ? 136.758 117.427 81.449  1.00 122.41 ? 351 GLU B CG  1 
ATOM   4402 C  CD  . GLU B 1 351 ? 137.642 116.198 81.440  1.00 128.61 ? 351 GLU B CD  1 
ATOM   4403 O  OE1 . GLU B 1 351 ? 137.259 115.192 80.809  1.00 128.51 ? 351 GLU B OE1 1 
ATOM   4404 O  OE2 . GLU B 1 351 ? 138.723 116.239 82.065  1.00 124.98 ? 351 GLU B OE2 1 
ATOM   4405 N  N   . ALA B 1 352 ? 134.093 118.219 83.686  1.00 108.74 ? 352 ALA B N   1 
ATOM   4406 C  CA  . ALA B 1 352 ? 134.271 118.870 84.978  1.00 104.33 ? 352 ALA B CA  1 
ATOM   4407 C  C   . ALA B 1 352 ? 133.697 118.026 86.106  1.00 109.59 ? 352 ALA B C   1 
ATOM   4408 O  O   . ALA B 1 352 ? 134.315 117.899 87.170  1.00 118.44 ? 352 ALA B O   1 
ATOM   4409 C  CB  . ALA B 1 352 ? 133.627 120.254 84.960  1.00 103.69 ? 352 ALA B CB  1 
ATOM   4410 N  N   . SER B 1 353 ? 132.515 117.441 85.897  1.00 112.48 ? 353 SER B N   1 
ATOM   4411 C  CA  . SER B 1 353 ? 131.926 116.594 86.926  1.00 109.87 ? 353 SER B CA  1 
ATOM   4412 C  C   . SER B 1 353 ? 132.797 115.377 87.199  1.00 112.72 ? 353 SER B C   1 
ATOM   4413 O  O   . SER B 1 353 ? 133.020 115.012 88.361  1.00 117.47 ? 353 SER B O   1 
ATOM   4414 C  CB  . SER B 1 353 ? 130.523 116.165 86.508  1.00 115.50 ? 353 SER B CB  1 
ATOM   4415 O  OG  . SER B 1 353 ? 129.829 117.235 85.895  1.00 120.33 ? 353 SER B OG  1 
ATOM   4416 N  N   . SER B 1 354 ? 133.306 114.739 86.142  1.00 116.62 ? 354 SER B N   1 
ATOM   4417 C  CA  . SER B 1 354 ? 134.168 113.579 86.329  1.00 115.96 ? 354 SER B CA  1 
ATOM   4418 C  C   . SER B 1 354 ? 135.443 113.955 87.068  1.00 118.51 ? 354 SER B C   1 
ATOM   4419 O  O   . SER B 1 354 ? 135.876 113.237 87.978  1.00 121.12 ? 354 SER B O   1 
ATOM   4420 C  CB  . SER B 1 354 ? 134.500 112.948 84.979  1.00 114.30 ? 354 SER B CB  1 
ATOM   4421 O  OG  . SER B 1 354 ? 133.320 112.588 84.285  1.00 123.27 ? 354 SER B OG  1 
ATOM   4422 N  N   . ARG B 1 355 ? 136.056 115.081 86.696  1.00 116.50 ? 355 ARG B N   1 
ATOM   4423 C  CA  . ARG B 1 355 ? 137.282 115.508 87.359  1.00 109.75 ? 355 ARG B CA  1 
ATOM   4424 C  C   . ARG B 1 355 ? 137.039 115.794 88.832  1.00 107.20 ? 355 ARG B C   1 
ATOM   4425 O  O   . ARG B 1 355 ? 137.825 115.376 89.688  1.00 118.83 ? 355 ARG B O   1 
ATOM   4426 C  CB  . ARG B 1 355 ? 137.850 116.743 86.666  1.00 108.13 ? 355 ARG B CB  1 
ATOM   4427 C  CG  . ARG B 1 355 ? 138.650 116.435 85.423  1.00 112.84 ? 355 ARG B CG  1 
ATOM   4428 C  CD  . ARG B 1 355 ? 139.487 117.622 85.003  1.00 110.64 ? 355 ARG B CD  1 
ATOM   4429 N  NE  . ARG B 1 355 ? 140.029 117.447 83.663  1.00 116.79 ? 355 ARG B NE  1 
ATOM   4430 C  CZ  . ARG B 1 355 ? 140.864 118.294 83.077  1.00 122.65 ? 355 ARG B CZ  1 
ATOM   4431 N  NH1 . ARG B 1 355 ? 141.277 119.390 83.689  1.00 122.02 ? 355 ARG B NH1 1 
ATOM   4432 N  NH2 . ARG B 1 355 ? 141.293 118.033 81.846  1.00 120.89 ? 355 ARG B NH2 1 
ATOM   4433 N  N   . LEU B 1 356 ? 135.956 116.505 89.148  1.00 104.52 ? 356 LEU B N   1 
ATOM   4434 C  CA  . LEU B 1 356 ? 135.667 116.809 90.544  1.00 110.91 ? 356 LEU B CA  1 
ATOM   4435 C  C   . LEU B 1 356 ? 135.405 115.540 91.341  1.00 113.37 ? 356 LEU B C   1 
ATOM   4436 O  O   . LEU B 1 356 ? 135.929 115.377 92.449  1.00 118.27 ? 356 LEU B O   1 
ATOM   4437 C  CB  . LEU B 1 356 ? 134.477 117.761 90.640  1.00 111.00 ? 356 LEU B CB  1 
ATOM   4438 C  CG  . LEU B 1 356 ? 134.769 119.231 90.340  1.00 107.40 ? 356 LEU B CG  1 
ATOM   4439 C  CD1 . LEU B 1 356 ? 133.645 120.106 90.846  1.00 109.81 ? 356 LEU B CD1 1 
ATOM   4440 C  CD2 . LEU B 1 356 ? 136.089 119.651 90.953  1.00 110.96 ? 356 LEU B CD2 1 
ATOM   4441 N  N   . TYR B 1 357 ? 134.613 114.619 90.786  1.00 121.75 ? 357 TYR B N   1 
ATOM   4442 C  CA  . TYR B 1 357 ? 134.308 113.388 91.505  1.00 121.33 ? 357 TYR B CA  1 
ATOM   4443 C  C   . TYR B 1 357 ? 135.561 112.554 91.733  1.00 124.33 ? 357 TYR B C   1 
ATOM   4444 O  O   . TYR B 1 357 ? 135.755 111.996 92.819  1.00 126.44 ? 357 TYR B O   1 
ATOM   4445 C  CB  . TYR B 1 357 ? 133.261 112.578 90.743  1.00 120.31 ? 357 TYR B CB  1 
ATOM   4446 C  CG  . TYR B 1 357 ? 133.016 111.207 91.326  1.00 125.37 ? 357 TYR B CG  1 
ATOM   4447 C  CD1 . TYR B 1 357 ? 132.795 111.038 92.686  1.00 123.62 ? 357 TYR B CD1 1 
ATOM   4448 C  CD2 . TYR B 1 357 ? 133.016 110.078 90.519  1.00 128.38 ? 357 TYR B CD2 1 
ATOM   4449 C  CE1 . TYR B 1 357 ? 132.575 109.787 93.225  1.00 124.70 ? 357 TYR B CE1 1 
ATOM   4450 C  CE2 . TYR B 1 357 ? 132.797 108.822 91.049  1.00 130.08 ? 357 TYR B CE2 1 
ATOM   4451 C  CZ  . TYR B 1 357 ? 132.577 108.683 92.401  1.00 130.13 ? 357 TYR B CZ  1 
ATOM   4452 O  OH  . TYR B 1 357 ? 132.358 107.434 92.933  1.00 125.71 ? 357 TYR B OH  1 
ATOM   4453 N  N   . SER B 1 358 ? 136.426 112.454 90.724  1.00 118.43 ? 358 SER B N   1 
ATOM   4454 C  CA  . SER B 1 358 ? 137.619 111.627 90.862  1.00 115.65 ? 358 SER B CA  1 
ATOM   4455 C  C   . SER B 1 358 ? 138.618 112.252 91.827  1.00 119.68 ? 358 SER B C   1 
ATOM   4456 O  O   . SER B 1 358 ? 139.155 111.569 92.706  1.00 122.40 ? 358 SER B O   1 
ATOM   4457 C  CB  . SER B 1 358 ? 138.259 111.403 89.494  1.00 117.69 ? 358 SER B CB  1 
ATOM   4458 O  OG  . SER B 1 358 ? 139.117 112.476 89.155  1.00 121.43 ? 358 SER B OG  1 
ATOM   4459 N  N   . ARG B 1 359 ? 138.883 113.551 91.682  1.00 114.58 ? 359 ARG B N   1 
ATOM   4460 C  CA  . ARG B 1 359 ? 139.924 114.188 92.478  1.00 106.91 ? 359 ARG B CA  1 
ATOM   4461 C  C   . ARG B 1 359 ? 139.492 114.419 93.921  1.00 112.46 ? 359 ARG B C   1 
ATOM   4462 O  O   . ARG B 1 359 ? 140.281 114.196 94.844  1.00 112.85 ? 359 ARG B O   1 
ATOM   4463 C  CB  . ARG B 1 359 ? 140.334 115.510 91.833  1.00 111.03 ? 359 ARG B CB  1 
ATOM   4464 C  CG  . ARG B 1 359 ? 141.831 115.738 91.783  1.00 115.98 ? 359 ARG B CG  1 
ATOM   4465 C  CD  . ARG B 1 359 ? 142.210 116.605 90.597  1.00 117.02 ? 359 ARG B CD  1 
ATOM   4466 N  NE  . ARG B 1 359 ? 141.897 115.957 89.329  1.00 122.44 ? 359 ARG B NE  1 
ATOM   4467 C  CZ  . ARG B 1 359 ? 142.185 116.464 88.138  1.00 123.28 ? 359 ARG B CZ  1 
ATOM   4468 N  NH1 . ARG B 1 359 ? 142.788 117.635 88.013  1.00 114.79 ? 359 ARG B NH1 1 
ATOM   4469 N  NH2 . ARG B 1 359 ? 141.860 115.779 87.046  1.00 122.26 ? 359 ARG B NH2 1 
ATOM   4470 N  N   . PHE B 1 360 ? 138.257 114.869 94.144  1.00 104.99 ? 360 PHE B N   1 
ATOM   4471 C  CA  . PHE B 1 360 ? 137.842 115.297 95.470  1.00 106.32 ? 360 PHE B CA  1 
ATOM   4472 C  C   . PHE B 1 360 ? 136.691 114.496 96.058  1.00 109.98 ? 360 PHE B C   1 
ATOM   4473 O  O   . PHE B 1 360 ? 136.421 114.633 97.256  1.00 109.69 ? 360 PHE B O   1 
ATOM   4474 C  CB  . PHE B 1 360 ? 137.459 116.784 95.451  1.00 107.91 ? 360 PHE B CB  1 
ATOM   4475 C  CG  . PHE B 1 360 ? 138.514 117.666 94.855  1.00 108.64 ? 360 PHE B CG  1 
ATOM   4476 C  CD1 . PHE B 1 360 ? 139.554 118.139 95.630  1.00 109.48 ? 360 PHE B CD1 1 
ATOM   4477 C  CD2 . PHE B 1 360 ? 138.470 118.013 93.519  1.00 103.78 ? 360 PHE B CD2 1 
ATOM   4478 C  CE1 . PHE B 1 360 ? 140.527 118.943 95.084  1.00 109.24 ? 360 PHE B CE1 1 
ATOM   4479 C  CE2 . PHE B 1 360 ? 139.440 118.817 92.970  1.00 103.72 ? 360 PHE B CE2 1 
ATOM   4480 C  CZ  . PHE B 1 360 ? 140.470 119.282 93.753  1.00 108.27 ? 360 PHE B CZ  1 
ATOM   4481 N  N   . GLY B 1 361 ? 136.010 113.674 95.267  1.00 116.92 ? 361 GLY B N   1 
ATOM   4482 C  CA  . GLY B 1 361 ? 134.951 112.838 95.794  1.00 118.62 ? 361 GLY B CA  1 
ATOM   4483 C  C   . GLY B 1 361 ? 133.785 113.612 96.368  1.00 116.62 ? 361 GLY B C   1 
ATOM   4484 O  O   . GLY B 1 361 ? 133.316 113.313 97.470  1.00 114.37 ? 361 GLY B O   1 
ATOM   4485 N  N   . PHE B 1 362 ? 133.315 114.618 95.639  1.00 114.68 ? 362 PHE B N   1 
ATOM   4486 C  CA  . PHE B 1 362 ? 132.165 115.386 96.090  1.00 109.71 ? 362 PHE B CA  1 
ATOM   4487 C  C   . PHE B 1 362 ? 130.901 114.547 95.975  1.00 111.68 ? 362 PHE B C   1 
ATOM   4488 O  O   . PHE B 1 362 ? 130.624 113.961 94.925  1.00 113.03 ? 362 PHE B O   1 
ATOM   4489 C  CB  . PHE B 1 362 ? 132.029 116.665 95.269  1.00 101.21 ? 362 PHE B CB  1 
ATOM   4490 C  CG  . PHE B 1 362 ? 133.025 117.722 95.632  1.00 104.15 ? 362 PHE B CG  1 
ATOM   4491 C  CD1 . PHE B 1 362 ? 133.077 118.228 96.915  1.00 101.85 ? 362 PHE B CD1 1 
ATOM   4492 C  CD2 . PHE B 1 362 ? 133.911 118.207 94.692  1.00 107.94 ? 362 PHE B CD2 1 
ATOM   4493 C  CE1 . PHE B 1 362 ? 133.990 119.197 97.253  1.00 97.38  ? 362 PHE B CE1 1 
ATOM   4494 C  CE2 . PHE B 1 362 ? 134.826 119.177 95.026  1.00 106.94 ? 362 PHE B CE2 1 
ATOM   4495 C  CZ  . PHE B 1 362 ? 134.865 119.672 96.308  1.00 100.47 ? 362 PHE B CZ  1 
ATOM   4496 N  N   . SER B 1 363 ? 130.135 114.483 97.065  1.00 104.29 ? 363 SER B N   1 
ATOM   4497 C  CA  . SER B 1 363 ? 128.888 113.728 97.043  1.00 101.04 ? 363 SER B CA  1 
ATOM   4498 C  C   . SER B 1 363 ? 127.868 114.376 96.117  1.00 105.54 ? 363 SER B C   1 
ATOM   4499 O  O   . SER B 1 363 ? 127.131 113.679 95.412  1.00 107.79 ? 363 SER B O   1 
ATOM   4500 C  CB  . SER B 1 363 ? 128.332 113.602 98.458  1.00 104.82 ? 363 SER B CB  1 
ATOM   4501 O  OG  . SER B 1 363 ? 129.319 113.110 99.345  1.00 112.55 ? 363 SER B OG  1 
ATOM   4502 N  N   . SER B 1 364 ? 127.810 115.703 96.108  1.00 111.26 ? 364 SER B N   1 
ATOM   4503 C  CA  . SER B 1 364 ? 126.920 116.449 95.234  1.00 108.69 ? 364 SER B CA  1 
ATOM   4504 C  C   . SER B 1 364 ? 127.715 117.533 94.527  1.00 110.03 ? 364 SER B C   1 
ATOM   4505 O  O   . SER B 1 364 ? 128.624 118.127 95.112  1.00 119.02 ? 364 SER B O   1 
ATOM   4506 C  CB  . SER B 1 364 ? 125.761 117.068 96.018  1.00 113.37 ? 364 SER B CB  1 
ATOM   4507 O  OG  . SER B 1 364 ? 124.843 117.710 95.152  1.00 116.73 ? 364 SER B OG  1 
ATOM   4508 N  N   . CYS B 1 365 ? 127.375 117.786 93.267  1.00 107.94 ? 365 CYS B N   1 
ATOM   4509 C  CA  . CYS B 1 365 ? 128.095 118.770 92.467  1.00 103.82 ? 365 CYS B CA  1 
ATOM   4510 C  C   . CYS B 1 365 ? 127.148 119.346 91.428  1.00 111.54 ? 365 CYS B C   1 
ATOM   4511 O  O   . CYS B 1 365 ? 126.622 118.605 90.594  1.00 117.15 ? 365 CYS B O   1 
ATOM   4512 C  CB  . CYS B 1 365 ? 129.314 118.141 91.796  1.00 106.74 ? 365 CYS B CB  1 
ATOM   4513 S  SG  . CYS B 1 365 ? 130.158 119.216 90.626  1.00 131.72 ? 365 CYS B SG  1 
ATOM   4514 N  N   . THR B 1 366 ? 126.939 120.658 91.476  1.00 97.37  ? 366 THR B N   1 
ATOM   4515 C  CA  . THR B 1 366 ? 126.090 121.363 90.524  1.00 95.78  ? 366 THR B CA  1 
ATOM   4516 C  C   . THR B 1 366 ? 126.907 122.468 89.877  1.00 97.52  ? 366 THR B C   1 
ATOM   4517 O  O   . THR B 1 366 ? 127.393 123.367 90.568  1.00 111.72 ? 366 THR B O   1 
ATOM   4518 C  CB  . THR B 1 366 ? 124.856 121.947 91.213  1.00 96.86  ? 366 THR B CB  1 
ATOM   4519 O  OG1 . THR B 1 366 ? 124.097 120.891 91.810  1.00 105.99 ? 366 THR B OG1 1 
ATOM   4520 C  CG2 . THR B 1 366 ? 123.987 122.678 90.211  1.00 94.87  ? 366 THR B CG2 1 
ATOM   4521 N  N   . LEU B 1 367 ? 127.054 122.406 88.558  1.00 91.09  ? 367 LEU B N   1 
ATOM   4522 C  CA  . LEU B 1 367 ? 127.847 123.373 87.812  1.00 87.70  ? 367 LEU B CA  1 
ATOM   4523 C  C   . LEU B 1 367 ? 126.955 124.070 86.799  1.00 92.88  ? 367 LEU B C   1 
ATOM   4524 O  O   . LEU B 1 367 ? 126.309 123.410 85.980  1.00 105.25 ? 367 LEU B O   1 
ATOM   4525 C  CB  . LEU B 1 367 ? 129.022 122.693 87.112  1.00 90.98  ? 367 LEU B CB  1 
ATOM   4526 C  CG  . LEU B 1 367 ? 129.910 121.827 88.000  1.00 91.46  ? 367 LEU B CG  1 
ATOM   4527 C  CD1 . LEU B 1 367 ? 130.801 120.959 87.148  1.00 97.87  ? 367 LEU B CD1 1 
ATOM   4528 C  CD2 . LEU B 1 367 ? 130.735 122.687 88.931  1.00 94.81  ? 367 LEU B CD2 1 
ATOM   4529 N  N   . GLN B 1 368 ? 126.930 125.396 86.846  1.00 93.71  ? 368 GLN B N   1 
ATOM   4530 C  CA  . GLN B 1 368 ? 126.158 126.200 85.908  1.00 91.49  ? 368 GLN B CA  1 
ATOM   4531 C  C   . GLN B 1 368 ? 127.088 126.652 84.791  1.00 98.34  ? 368 GLN B C   1 
ATOM   4532 O  O   . GLN B 1 368 ? 127.965 127.491 85.008  1.00 110.33 ? 368 GLN B O   1 
ATOM   4533 C  CB  . GLN B 1 368 ? 125.521 127.396 86.607  1.00 94.58  ? 368 GLN B CB  1 
ATOM   4534 C  CG  . GLN B 1 368 ? 124.839 128.356 85.662  1.00 97.98  ? 368 GLN B CG  1 
ATOM   4535 C  CD  . GLN B 1 368 ? 124.022 129.396 86.386  1.00 103.04 ? 368 GLN B CD  1 
ATOM   4536 O  OE1 . GLN B 1 368 ? 123.520 129.153 87.479  1.00 109.00 ? 368 GLN B OE1 1 
ATOM   4537 N  NE2 . GLN B 1 368 ? 123.886 130.566 85.782  1.00 108.92 ? 368 GLN B NE2 1 
ATOM   4538 N  N   . VAL B 1 369 ? 126.897 126.096 83.601  1.00 98.18  ? 369 VAL B N   1 
ATOM   4539 C  CA  . VAL B 1 369 ? 127.744 126.400 82.456  1.00 98.42  ? 369 VAL B CA  1 
ATOM   4540 C  C   . VAL B 1 369 ? 127.170 127.626 81.757  1.00 100.57 ? 369 VAL B C   1 
ATOM   4541 O  O   . VAL B 1 369 ? 126.154 127.541 81.063  1.00 111.39 ? 369 VAL B O   1 
ATOM   4542 C  CB  . VAL B 1 369 ? 127.846 125.206 81.502  1.00 97.85  ? 369 VAL B CB  1 
ATOM   4543 C  CG1 . VAL B 1 369 ? 128.542 125.612 80.223  1.00 100.44 ? 369 VAL B CG1 1 
ATOM   4544 C  CG2 . VAL B 1 369 ? 128.592 124.070 82.170  1.00 100.08 ? 369 VAL B CG2 1 
ATOM   4545 N  N   . GLU B 1 370 ? 127.820 128.768 81.944  1.00 110.80 ? 370 GLU B N   1 
ATOM   4546 C  CA  . GLU B 1 370 ? 127.427 130.015 81.315  1.00 110.03 ? 370 GLU B CA  1 
ATOM   4547 C  C   . GLU B 1 370 ? 128.271 130.242 80.065  1.00 114.56 ? 370 GLU B C   1 
ATOM   4548 O  O   . GLU B 1 370 ? 129.119 129.427 79.700  1.00 120.63 ? 370 GLU B O   1 
ATOM   4549 C  CB  . GLU B 1 370 ? 127.571 131.177 82.301  1.00 111.91 ? 370 GLU B CB  1 
ATOM   4550 C  CG  . GLU B 1 370 ? 126.541 131.175 83.415  1.00 110.25 ? 370 GLU B CG  1 
ATOM   4551 C  CD  . GLU B 1 370 ? 127.026 131.874 84.670  1.00 118.56 ? 370 GLU B CD  1 
ATOM   4552 O  OE1 . GLU B 1 370 ? 128.174 132.358 84.687  1.00 125.34 ? 370 GLU B OE1 1 
ATOM   4553 O  OE2 . GLU B 1 370 ? 126.253 131.950 85.645  1.00 127.20 ? 370 GLU B OE2 1 
ATOM   4554 N  N   . GLN B 1 371 ? 128.030 131.363 79.397  1.00 125.67 ? 371 GLN B N   1 
ATOM   4555 C  CA  . GLN B 1 371 ? 128.802 131.766 78.230  1.00 121.35 ? 371 GLN B CA  1 
ATOM   4556 C  C   . GLN B 1 371 ? 129.669 132.958 78.599  1.00 130.54 ? 371 GLN B C   1 
ATOM   4557 O  O   . GLN B 1 371 ? 129.182 133.922 79.197  1.00 135.46 ? 371 GLN B O   1 
ATOM   4558 C  CB  . GLN B 1 371 ? 127.887 132.114 77.056  1.00 121.16 ? 371 GLN B CB  1 
ATOM   4559 C  CG  . GLN B 1 371 ? 127.299 130.904 76.364  1.00 125.14 ? 371 GLN B CG  1 
ATOM   4560 C  CD  . GLN B 1 371 ? 128.163 130.416 75.223  1.00 127.93 ? 371 GLN B CD  1 
ATOM   4561 O  OE1 . GLN B 1 371 ? 128.838 131.203 74.563  1.00 130.15 ? 371 GLN B OE1 1 
ATOM   4562 N  NE2 . GLN B 1 371 ? 128.147 129.111 74.984  1.00 125.05 ? 371 GLN B NE2 1 
ATOM   4563 N  N   . TYR B 1 372 ? 130.950 132.892 78.247  1.00 139.93 ? 372 TYR B N   1 
ATOM   4564 C  CA  . TYR B 1 372 ? 131.905 133.915 78.662  1.00 140.35 ? 372 TYR B CA  1 
ATOM   4565 C  C   . TYR B 1 372 ? 131.720 135.151 77.795  1.00 141.16 ? 372 TYR B C   1 
ATOM   4566 O  O   . TYR B 1 372 ? 132.326 135.292 76.733  1.00 140.33 ? 372 TYR B O   1 
ATOM   4567 C  CB  . TYR B 1 372 ? 133.333 133.398 78.574  1.00 143.39 ? 372 TYR B CB  1 
ATOM   4568 C  CG  . TYR B 1 372 ? 134.357 134.450 78.923  1.00 144.33 ? 372 TYR B CG  1 
ATOM   4569 C  CD1 . TYR B 1 372 ? 134.391 135.014 80.189  1.00 141.53 ? 372 TYR B CD1 1 
ATOM   4570 C  CD2 . TYR B 1 372 ? 135.277 134.891 77.984  1.00 140.70 ? 372 TYR B CD2 1 
ATOM   4571 C  CE1 . TYR B 1 372 ? 135.318 135.979 80.515  1.00 140.51 ? 372 TYR B CE1 1 
ATOM   4572 C  CE2 . TYR B 1 372 ? 136.208 135.857 78.301  1.00 141.87 ? 372 TYR B CE2 1 
ATOM   4573 C  CZ  . TYR B 1 372 ? 136.224 136.397 79.568  1.00 144.12 ? 372 TYR B CZ  1 
ATOM   4574 O  OH  . TYR B 1 372 ? 137.150 137.360 79.890  1.00 145.93 ? 372 TYR B OH  1 
ATOM   4575 N  N   . GLN B 1 373 ? 130.869 136.059 78.256  1.00 160.08 ? 373 GLN B N   1 
ATOM   4576 C  CA  . GLN B 1 373 ? 130.763 137.358 77.620  1.00 162.03 ? 373 GLN B CA  1 
ATOM   4577 C  C   . GLN B 1 373 ? 131.993 138.199 77.955  1.00 162.56 ? 373 GLN B C   1 
ATOM   4578 O  O   . GLN B 1 373 ? 132.641 137.984 78.982  1.00 160.44 ? 373 GLN B O   1 
ATOM   4579 C  CB  . GLN B 1 373 ? 129.500 138.078 78.080  1.00 160.29 ? 373 GLN B CB  1 
ATOM   4580 C  CG  . GLN B 1 373 ? 128.355 137.151 78.440  1.00 160.94 ? 373 GLN B CG  1 
ATOM   4581 C  CD  . GLN B 1 373 ? 127.419 136.905 77.276  1.00 163.05 ? 373 GLN B CD  1 
ATOM   4582 O  OE1 . GLN B 1 373 ? 127.832 136.933 76.117  1.00 162.96 ? 373 GLN B OE1 1 
ATOM   4583 N  NE2 . GLN B 1 373 ? 126.150 136.662 77.578  1.00 161.61 ? 373 GLN B NE2 1 
ATOM   4584 N  N   . PRO B 1 374 ? 132.346 139.158 77.097  1.00 175.19 ? 374 PRO B N   1 
ATOM   4585 C  CA  . PRO B 1 374 ? 133.456 140.063 77.436  1.00 174.54 ? 374 PRO B CA  1 
ATOM   4586 C  C   . PRO B 1 374 ? 133.202 140.880 78.689  1.00 174.11 ? 374 PRO B C   1 
ATOM   4587 O  O   . PRO B 1 374 ? 134.163 141.347 79.312  1.00 171.84 ? 374 PRO B O   1 
ATOM   4588 C  CB  . PRO B 1 374 ? 133.574 140.957 76.195  1.00 173.60 ? 374 PRO B CB  1 
ATOM   4589 C  CG  . PRO B 1 374 ? 132.962 140.157 75.092  1.00 173.10 ? 374 PRO B CG  1 
ATOM   4590 C  CD  . PRO B 1 374 ? 131.854 139.374 75.727  1.00 173.00 ? 374 PRO B CD  1 
ATOM   4591 N  N   . GLU B 1 375 ? 131.941 141.068 79.079  1.00 180.91 ? 375 GLU B N   1 
ATOM   4592 C  CA  . GLU B 1 375 ? 131.609 141.805 80.290  1.00 181.16 ? 375 GLU B CA  1 
ATOM   4593 C  C   . GLU B 1 375 ? 131.739 140.964 81.553  1.00 182.33 ? 375 GLU B C   1 
ATOM   4594 O  O   . GLU B 1 375 ? 131.618 141.512 82.654  1.00 182.63 ? 375 GLU B O   1 
ATOM   4595 C  CB  . GLU B 1 375 ? 130.185 142.359 80.187  1.00 180.82 ? 375 GLU B CB  1 
ATOM   4596 C  CG  . GLU B 1 375 ? 129.968 143.671 80.921  1.00 182.22 ? 375 GLU B CG  1 
ATOM   4597 C  CD  . GLU B 1 375 ? 129.143 143.500 82.180  1.00 182.47 ? 375 GLU B CD  1 
ATOM   4598 O  OE1 . GLU B 1 375 ? 128.850 142.343 82.545  1.00 182.85 ? 375 GLU B OE1 1 
ATOM   4599 O  OE2 . GLU B 1 375 ? 128.786 144.522 82.804  1.00 179.62 ? 375 GLU B OE2 1 
ATOM   4600 N  N   . MET B 1 376 ? 131.978 139.656 81.424  1.00 178.91 ? 376 MET B N   1 
ATOM   4601 C  CA  . MET B 1 376 ? 132.130 138.808 82.603  1.00 178.02 ? 376 MET B CA  1 
ATOM   4602 C  C   . MET B 1 376 ? 133.334 139.226 83.436  1.00 178.29 ? 376 MET B C   1 
ATOM   4603 O  O   . MET B 1 376 ? 133.266 139.252 84.671  1.00 176.76 ? 376 MET B O   1 
ATOM   4604 C  CB  . MET B 1 376 ? 132.255 137.343 82.184  1.00 177.65 ? 376 MET B CB  1 
ATOM   4605 C  CG  . MET B 1 376 ? 131.056 136.792 81.431  1.00 177.71 ? 376 MET B CG  1 
ATOM   4606 S  SD  . MET B 1 376 ? 130.384 135.292 82.171  1.00 177.67 ? 376 MET B SD  1 
ATOM   4607 C  CE  . MET B 1 376 ? 129.397 135.972 83.496  1.00 176.31 ? 376 MET B CE  1 
ATOM   4608 N  N   . ALA B 1 377 ? 134.444 139.559 82.782  1.00 186.72 ? 377 ALA B N   1 
ATOM   4609 C  CA  . ALA B 1 377 ? 135.669 139.942 83.471  1.00 186.50 ? 377 ALA B CA  1 
ATOM   4610 C  C   . ALA B 1 377 ? 135.632 141.368 84.005  1.00 187.99 ? 377 ALA B C   1 
ATOM   4611 O  O   . ALA B 1 377 ? 136.671 141.880 84.434  1.00 187.83 ? 377 ALA B O   1 
ATOM   4612 C  CB  . ALA B 1 377 ? 136.872 139.771 82.540  1.00 184.77 ? 377 ALA B CB  1 
ATOM   4613 N  N   . GLN B 1 378 ? 134.468 142.018 83.988  1.00 195.29 ? 378 GLN B N   1 
ATOM   4614 C  CA  . GLN B 1 378 ? 134.329 143.372 84.499  1.00 193.94 ? 378 GLN B CA  1 
ATOM   4615 C  C   . GLN B 1 378 ? 133.432 143.472 85.722  1.00 193.43 ? 378 GLN B C   1 
ATOM   4616 O  O   . GLN B 1 378 ? 133.572 144.429 86.490  1.00 192.22 ? 378 GLN B O   1 
ATOM   4617 C  CB  . GLN B 1 378 ? 133.782 144.302 83.406  1.00 192.22 ? 378 GLN B CB  1 
ATOM   4618 C  CG  . GLN B 1 378 ? 134.161 145.761 83.584  1.00 193.33 ? 378 GLN B CG  1 
ATOM   4619 C  CD  . GLN B 1 378 ? 135.653 145.992 83.454  1.00 194.82 ? 378 GLN B CD  1 
ATOM   4620 O  OE1 . GLN B 1 378 ? 136.324 145.350 82.645  1.00 194.08 ? 378 GLN B OE1 1 
ATOM   4621 N  NE2 . GLN B 1 378 ? 136.181 146.911 84.253  1.00 194.17 ? 378 GLN B NE2 1 
ATOM   4622 N  N   . CYS B 1 379 ? 132.524 142.520 85.922  1.00 196.89 ? 379 CYS B N   1 
ATOM   4623 C  CA  . CYS B 1 379 ? 131.625 142.571 87.065  1.00 196.88 ? 379 CYS B CA  1 
ATOM   4624 C  C   . CYS B 1 379 ? 132.395 142.383 88.365  1.00 196.55 ? 379 CYS B C   1 
ATOM   4625 O  O   . CYS B 1 379 ? 133.275 141.524 88.467  1.00 197.34 ? 379 CYS B O   1 
ATOM   4626 C  CB  . CYS B 1 379 ? 130.541 141.502 86.939  1.00 197.29 ? 379 CYS B CB  1 
ATOM   4627 S  SG  . CYS B 1 379 ? 129.348 141.495 88.297  1.00 201.30 ? 379 CYS B SG  1 
ATOM   4628 N  N   . LEU B 1 380 ? 132.061 143.203 89.362  1.00 191.20 ? 380 LEU B N   1 
ATOM   4629 C  CA  . LEU B 1 380 ? 132.712 143.089 90.662  1.00 191.85 ? 380 LEU B CA  1 
ATOM   4630 C  C   . LEU B 1 380 ? 132.345 141.780 91.350  1.00 193.78 ? 380 LEU B C   1 
ATOM   4631 O  O   . LEU B 1 380 ? 133.193 141.151 91.994  1.00 192.56 ? 380 LEU B O   1 
ATOM   4632 C  CB  . LEU B 1 380 ? 132.340 144.284 91.540  1.00 192.34 ? 380 LEU B CB  1 
ATOM   4633 C  CG  . LEU B 1 380 ? 132.881 144.292 92.972  1.00 193.31 ? 380 LEU B CG  1 
ATOM   4634 C  CD1 . LEU B 1 380 ? 133.571 145.612 93.275  1.00 190.72 ? 380 LEU B CD1 1 
ATOM   4635 C  CD2 . LEU B 1 380 ? 131.768 144.026 93.975  1.00 192.31 ? 380 LEU B CD2 1 
ATOM   4636 N  N   . ARG B 1 381 ? 131.087 141.353 91.225  1.00 196.36 ? 381 ARG B N   1 
ATOM   4637 C  CA  . ARG B 1 381 ? 130.642 140.140 91.899  1.00 194.28 ? 381 ARG B CA  1 
ATOM   4638 C  C   . ARG B 1 381 ? 131.150 138.874 91.223  1.00 193.54 ? 381 ARG B C   1 
ATOM   4639 O  O   . ARG B 1 381 ? 131.085 137.798 91.826  1.00 192.70 ? 381 ARG B O   1 
ATOM   4640 C  CB  . ARG B 1 381 ? 129.115 140.111 91.973  1.00 193.40 ? 381 ARG B CB  1 
ATOM   4641 C  CG  . ARG B 1 381 ? 128.480 141.475 92.171  1.00 193.39 ? 381 ARG B CG  1 
ATOM   4642 C  CD  . ARG B 1 381 ? 127.161 141.577 91.427  1.00 194.17 ? 381 ARG B CD  1 
ATOM   4643 N  NE  . ARG B 1 381 ? 126.327 140.401 91.644  1.00 195.12 ? 381 ARG B NE  1 
ATOM   4644 C  CZ  . ARG B 1 381 ? 125.567 140.209 92.713  1.00 195.51 ? 381 ARG B CZ  1 
ATOM   4645 N  NH1 . ARG B 1 381 ? 125.508 141.100 93.689  1.00 194.60 ? 381 ARG B NH1 1 
ATOM   4646 N  NH2 . ARG B 1 381 ? 124.848 139.093 92.805  1.00 194.58 ? 381 ARG B NH2 1 
ATOM   4647 N  N   . CYS B 1 382 ? 131.645 138.971 89.990  1.00 186.17 ? 382 CYS B N   1 
ATOM   4648 C  CA  . CYS B 1 382 ? 132.177 137.823 89.270  1.00 184.05 ? 382 CYS B CA  1 
ATOM   4649 C  C   . CYS B 1 382 ? 133.668 137.622 89.512  1.00 185.06 ? 382 CYS B C   1 
ATOM   4650 O  O   . CYS B 1 382 ? 134.347 137.018 88.675  1.00 184.38 ? 382 CYS B O   1 
ATOM   4651 C  CB  . CYS B 1 382 ? 131.902 137.966 87.771  1.00 183.63 ? 382 CYS B CB  1 
ATOM   4652 S  SG  . CYS B 1 382 ? 130.165 137.789 87.303  1.00 189.33 ? 382 CYS B SG  1 
ATOM   4653 N  N   . GLN B 1 383 ? 134.188 138.113 90.633  1.00 183.86 ? 383 GLN B N   1 
ATOM   4654 C  CA  . GLN B 1 383 ? 135.598 137.990 90.973  1.00 182.31 ? 383 GLN B CA  1 
ATOM   4655 C  C   . GLN B 1 383 ? 135.763 137.084 92.185  1.00 181.85 ? 383 GLN B C   1 
ATOM   4656 O  O   . GLN B 1 383 ? 135.013 137.191 93.160  1.00 181.77 ? 383 GLN B O   1 
ATOM   4657 C  CB  . GLN B 1 383 ? 136.217 139.361 91.257  1.00 181.59 ? 383 GLN B CB  1 
ATOM   4658 C  CG  . GLN B 1 383 ? 135.859 140.422 90.234  1.00 181.76 ? 383 GLN B CG  1 
ATOM   4659 C  CD  . GLN B 1 383 ? 136.475 140.150 88.878  1.00 182.55 ? 383 GLN B CD  1 
ATOM   4660 O  OE1 . GLN B 1 383 ? 137.564 139.586 88.780  1.00 182.34 ? 383 GLN B OE1 1 
ATOM   4661 N  NE2 . GLN B 1 383 ? 135.778 140.549 87.821  1.00 182.08 ? 383 GLN B NE2 1 
ATOM   4662 N  N   . GLU B 1 384 ? 136.751 136.196 92.118  1.00 165.74 ? 384 GLU B N   1 
ATOM   4663 C  CA  . GLU B 1 384 ? 136.990 135.252 93.193  1.00 168.58 ? 384 GLU B CA  1 
ATOM   4664 C  C   . GLU B 1 384 ? 137.535 135.969 94.428  1.00 166.24 ? 384 GLU B C   1 
ATOM   4665 O  O   . GLU B 1 384 ? 138.099 137.061 94.327  1.00 165.02 ? 384 GLU B O   1 
ATOM   4666 C  CB  . GLU B 1 384 ? 137.962 134.167 92.737  1.00 166.26 ? 384 GLU B CB  1 
ATOM   4667 C  CG  . GLU B 1 384 ? 137.509 133.418 91.492  1.00 164.27 ? 384 GLU B CG  1 
ATOM   4668 C  CD  . GLU B 1 384 ? 136.590 132.253 91.807  1.00 165.03 ? 384 GLU B CD  1 
ATOM   4669 O  OE1 . GLU B 1 384 ? 135.565 132.461 92.491  1.00 162.62 ? 384 GLU B OE1 1 
ATOM   4670 O  OE2 . GLU B 1 384 ? 136.891 131.125 91.367  1.00 165.51 ? 384 GLU B OE2 1 
ATOM   4671 N  N   . PRO B 1 385 ? 137.355 135.378 95.608  1.00 156.36 ? 385 PRO B N   1 
ATOM   4672 C  CA  . PRO B 1 385 ? 137.889 135.995 96.818  1.00 156.19 ? 385 PRO B CA  1 
ATOM   4673 C  C   . PRO B 1 385 ? 139.396 136.124 96.737  1.00 156.41 ? 385 PRO B C   1 
ATOM   4674 O  O   . PRO B 1 385 ? 140.075 135.298 96.100  1.00 153.40 ? 385 PRO B O   1 
ATOM   4675 C  CB  . PRO B 1 385 ? 137.468 135.023 97.931  1.00 155.72 ? 385 PRO B CB  1 
ATOM   4676 C  CG  . PRO B 1 385 ? 136.733 133.907 97.282  1.00 153.15 ? 385 PRO B CG  1 
ATOM   4677 C  CD  . PRO B 1 385 ? 136.399 134.299 95.896  1.00 156.06 ? 385 PRO B CD  1 
ATOM   4678 N  N   . PRO B 1 386 ? 139.964 137.150 97.365  1.00 170.28 ? 386 PRO B N   1 
ATOM   4679 C  CA  . PRO B 1 386 ? 141.414 137.350 97.291  1.00 168.41 ? 386 PRO B CA  1 
ATOM   4680 C  C   . PRO B 1 386 ? 142.166 136.296 98.089  1.00 170.58 ? 386 PRO B C   1 
ATOM   4681 O  O   . PRO B 1 386 ? 141.629 135.653 98.993  1.00 170.51 ? 386 PRO B O   1 
ATOM   4682 C  CB  . PRO B 1 386 ? 141.625 138.748 97.888  1.00 168.25 ? 386 PRO B CB  1 
ATOM   4683 C  CG  . PRO B 1 386 ? 140.269 139.240 98.319  1.00 168.30 ? 386 PRO B CG  1 
ATOM   4684 C  CD  . PRO B 1 386 ? 139.318 138.093 98.290  1.00 169.15 ? 386 PRO B CD  1 
ATOM   4685 N  N   . GLN B 1 387 ? 143.436 136.126 97.728  1.00 170.65 ? 387 GLN B N   1 
ATOM   4686 C  CA  . GLN B 1 387 ? 144.285 135.148 98.393  1.00 170.89 ? 387 GLN B CA  1 
ATOM   4687 C  C   . GLN B 1 387 ? 144.433 135.480 99.873  1.00 171.57 ? 387 GLN B C   1 
ATOM   4688 O  O   . GLN B 1 387 ? 144.516 136.648 100.261 1.00 170.28 ? 387 GLN B O   1 
ATOM   4689 C  CB  . GLN B 1 387 ? 145.660 135.104 97.726  1.00 170.04 ? 387 GLN B CB  1 
ATOM   4690 C  CG  . GLN B 1 387 ? 146.427 133.813 97.960  1.00 170.60 ? 387 GLN B CG  1 
ATOM   4691 C  CD  . GLN B 1 387 ? 146.421 132.905 96.748  1.00 170.01 ? 387 GLN B CD  1 
ATOM   4692 O  OE1 . GLN B 1 387 ? 145.399 132.748 96.080  1.00 169.56 ? 387 GLN B OE1 1 
ATOM   4693 N  NE2 . GLN B 1 387 ? 147.566 132.300 96.456  1.00 169.34 ? 387 GLN B NE2 1 
ATOM   4694 N  N   . ALA B 1 388 ? 144.460 134.441 100.700 1.00 179.70 ? 388 ALA B N   1 
ATOM   4695 C  CA  . ALA B 1 388 ? 144.606 134.613 102.139 1.00 179.89 ? 388 ALA B CA  1 
ATOM   4696 C  C   . ALA B 1 388 ? 146.036 134.999 102.498 1.00 180.10 ? 388 ALA B C   1 
ATOM   4697 O  O   . ALA B 1 388 ? 146.950 134.851 101.687 1.00 179.92 ? 388 ALA B O   1 
ATOM   4698 C  CB  . ALA B 1 388 ? 144.200 133.344 102.868 1.00 177.74 ? 388 ALA B CB  1 
HETATM 4699 ZN ZN  . ZN  C 2 .   ? 112.322 141.189 127.854 1.00 190.29 ? 801 ZN  A ZN  1 
HETATM 4700 ZN ZN  . ZN  D 2 .   ? 128.816 139.640 87.038  1.00 257.14 ? 802 ZN  A ZN  1 
HETATM 4701 C  C1  . AV0 E 3 .   ? 110.977 140.593 120.452 1.00 147.98 ? 803 AV0 A C1  1 
HETATM 4702 O  O1  . AV0 E 3 .   ? 112.056 141.246 119.900 1.00 146.57 ? 803 AV0 A O1  1 
HETATM 4703 C  C2  . AV0 E 3 .   ? 109.722 140.964 119.665 1.00 148.68 ? 803 AV0 A C2  1 
HETATM 4704 O  O2  . AV0 E 3 .   ? 109.279 142.257 119.973 1.00 152.29 ? 803 AV0 A O2  1 
HETATM 4705 C  C3  . AV0 E 3 .   ? 108.575 140.057 120.060 1.00 144.10 ? 803 AV0 A C3  1 
HETATM 4706 O  O3  . AV0 E 3 .   ? 107.438 140.308 119.269 1.00 142.67 ? 803 AV0 A O3  1 
HETATM 4707 C  C4  . AV0 E 3 .   ? 108.959 138.593 119.916 1.00 145.36 ? 803 AV0 A C4  1 
HETATM 4708 O  O4  . AV0 E 3 .   ? 107.826 137.867 120.335 1.00 151.18 ? 803 AV0 A O4  1 
HETATM 4709 C  C5  . AV0 E 3 .   ? 110.193 138.373 120.805 1.00 145.51 ? 803 AV0 A C5  1 
HETATM 4710 O  O5  . AV0 E 3 .   ? 111.229 139.218 120.350 1.00 146.13 ? 803 AV0 A O5  1 
HETATM 4711 C  C6  . AV0 E 3 .   ? 110.753 136.970 120.760 1.00 147.17 ? 803 AV0 A C6  1 
HETATM 4712 O  O6  . AV0 E 3 .   ? 112.158 137.068 120.752 1.00 149.26 ? 803 AV0 A O6  1 
HETATM 4713 C  CAA . AV0 E 3 .   ? 114.733 151.911 126.029 1.00 142.58 ? 803 AV0 A CAA 1 
HETATM 4714 C  CAB . AV0 E 3 .   ? 114.917 154.206 121.773 1.00 146.34 ? 803 AV0 A CAB 1 
HETATM 4715 O  OAI . AV0 E 3 .   ? 103.436 136.601 122.294 1.00 150.25 ? 803 AV0 A OAI 1 
HETATM 4716 O  OAJ . AV0 E 3 .   ? 116.154 134.524 114.781 1.00 149.46 ? 803 AV0 A OAJ 1 
HETATM 4717 O  OAL . AV0 E 3 .   ? 110.746 138.376 116.199 1.00 155.87 ? 803 AV0 A OAL 1 
HETATM 4718 O  OAN . AV0 E 3 .   ? 115.459 137.609 117.061 1.00 146.71 ? 803 AV0 A OAN 1 
HETATM 4719 O  OAP . AV0 E 3 .   ? 116.576 140.249 117.110 1.00 145.57 ? 803 AV0 A OAP 1 
HETATM 4720 O  OAQ . AV0 E 3 .   ? 103.551 138.050 120.207 1.00 146.46 ? 803 AV0 A OAQ 1 
HETATM 4721 O  OAR . AV0 E 3 .   ? 112.039 133.358 115.016 1.00 146.86 ? 803 AV0 A OAR 1 
HETATM 4722 O  OAS . AV0 E 3 .   ? 104.659 138.060 117.556 1.00 147.32 ? 803 AV0 A OAS 1 
HETATM 4723 O  OAT . AV0 E 3 .   ? 110.619 135.170 113.291 1.00 148.52 ? 803 AV0 A OAT 1 
HETATM 4724 O  OAU . AV0 E 3 .   ? 107.472 137.484 117.385 1.00 147.58 ? 803 AV0 A OAU 1 
HETATM 4725 O  OAV . AV0 E 3 .   ? 111.459 137.924 113.461 1.00 148.66 ? 803 AV0 A OAV 1 
HETATM 4726 C  CAW . AV0 E 3 .   ? 114.540 150.458 126.438 1.00 144.19 ? 803 AV0 A CAW 1 
HETATM 4727 C  CAX . AV0 E 3 .   ? 115.689 152.895 121.715 1.00 145.71 ? 803 AV0 A CAX 1 
HETATM 4728 C  CAY . AV0 E 3 .   ? 114.750 149.484 125.288 1.00 142.49 ? 803 AV0 A CAY 1 
HETATM 4729 C  CAZ . AV0 E 3 .   ? 114.924 151.802 120.983 1.00 142.18 ? 803 AV0 A CAZ 1 
HETATM 4730 C  CBA . AV0 E 3 .   ? 114.518 148.033 125.684 1.00 140.58 ? 803 AV0 A CBA 1 
HETATM 4731 C  CBB . AV0 E 3 .   ? 115.685 150.488 120.890 1.00 141.70 ? 803 AV0 A CBB 1 
HETATM 4732 C  CBC . AV0 E 3 .   ? 114.550 147.078 124.500 1.00 141.48 ? 803 AV0 A CBC 1 
HETATM 4733 C  CBD . AV0 E 3 .   ? 114.918 149.429 120.113 1.00 142.85 ? 803 AV0 A CBD 1 
HETATM 4734 C  CBE . AV0 E 3 .   ? 113.514 145.970 124.608 1.00 141.89 ? 803 AV0 A CBE 1 
HETATM 4735 C  CBF . AV0 E 3 .   ? 115.672 148.117 119.959 1.00 142.46 ? 803 AV0 A CBF 1 
HETATM 4736 C  CBG . AV0 E 3 .   ? 114.101 144.627 125.014 1.00 140.21 ? 803 AV0 A CBG 1 
HETATM 4737 C  CBH . AV0 E 3 .   ? 114.950 147.146 119.039 1.00 143.36 ? 803 AV0 A CBH 1 
HETATM 4738 C  CBI . AV0 E 3 .   ? 114.769 143.904 123.856 1.00 142.13 ? 803 AV0 A CBI 1 
HETATM 4739 C  CBJ . AV0 E 3 .   ? 115.770 145.914 118.693 1.00 141.89 ? 803 AV0 A CBJ 1 
HETATM 4740 C  CBK . AV0 E 3 .   ? 113.833 143.669 122.677 1.00 141.80 ? 803 AV0 A CBK 1 
HETATM 4741 C  CBL . AV0 E 3 .   ? 115.519 144.749 119.639 1.00 142.26 ? 803 AV0 A CBL 1 
HETATM 4742 C  CBM . AV0 E 3 .   ? 104.607 135.907 121.930 1.00 147.76 ? 803 AV0 A CBM 1 
HETATM 4743 C  CBN . AV0 E 3 .   ? 114.946 133.869 115.085 1.00 147.82 ? 803 AV0 A CBN 1 
HETATM 4744 C  CBP . AV0 E 3 .   ? 111.118 139.734 116.159 1.00 150.33 ? 803 AV0 A CBP 1 
HETATM 4745 C  CBQ . AV0 E 3 .   ? 114.511 142.853 121.584 1.00 142.52 ? 803 AV0 A CBQ 1 
HETATM 4746 C  CBR . AV0 E 3 .   ? 114.093 144.214 119.545 1.00 141.95 ? 803 AV0 A CBR 1 
HETATM 4747 C  CBS . AV0 E 3 .   ? 112.340 142.557 120.350 1.00 142.90 ? 803 AV0 A CBS 1 
HETATM 4748 C  CBT . AV0 E 3 .   ? 114.403 141.722 119.337 1.00 147.38 ? 803 AV0 A CBT 1 
HETATM 4749 O  OBV . AV0 E 3 .   ? 114.540 142.154 117.996 1.00 148.63 ? 803 AV0 A OBV 1 
HETATM 4750 O  OBX . AV0 E 3 .   ? 112.985 140.864 117.030 1.00 144.55 ? 803 AV0 A OBX 1 
HETATM 4751 O  OBY . AV0 E 3 .   ? 106.525 136.009 120.557 1.00 152.44 ? 803 AV0 A OBY 1 
HETATM 4752 O  OBZ . AV0 E 3 .   ? 114.369 136.107 114.612 1.00 151.96 ? 803 AV0 A OBZ 1 
HETATM 4753 O  OCB . AV0 E 3 .   ? 112.964 137.416 115.872 1.00 156.34 ? 803 AV0 A OCB 1 
HETATM 4754 C  CCC . AV0 E 3 .   ? 105.395 136.767 120.965 1.00 151.44 ? 803 AV0 A CCC 1 
HETATM 4755 C  CCD . AV0 E 3 .   ? 113.837 134.897 115.138 1.00 150.43 ? 803 AV0 A CCD 1 
HETATM 4756 C  CCF . AV0 E 3 .   ? 112.628 139.827 116.145 1.00 148.46 ? 803 AV0 A CCF 1 
HETATM 4757 C  CCH . AV0 E 3 .   ? 114.824 138.766 116.571 1.00 147.78 ? 803 AV0 A CCH 1 
HETATM 4758 C  CCJ . AV0 E 3 .   ? 114.349 141.193 117.031 1.00 147.40 ? 803 AV0 A CCJ 1 
HETATM 4759 C  CCL . AV0 E 3 .   ? 115.222 139.988 117.385 1.00 147.92 ? 803 AV0 A CCL 1 
HETATM 4760 C  CCM . AV0 E 3 .   ? 113.836 142.845 120.200 1.00 142.58 ? 803 AV0 A CCM 1 
HETATM 4761 C  CCN . AV0 E 3 .   ? 104.562 137.184 119.751 1.00 149.61 ? 803 AV0 A CCN 1 
HETATM 4762 C  CCO . AV0 E 3 .   ? 112.610 134.452 114.341 1.00 149.17 ? 803 AV0 A CCO 1 
HETATM 4763 C  CCQ . AV0 E 3 .   ? 113.317 138.549 116.638 1.00 150.14 ? 803 AV0 A CCQ 1 
HETATM 4764 C  CCR . AV0 E 3 .   ? 107.401 136.680 119.713 1.00 151.20 ? 803 AV0 A CCR 1 
HETATM 4765 C  CCS . AV0 E 3 .   ? 113.491 137.183 114.594 1.00 150.80 ? 803 AV0 A CCS 1 
HETATM 4766 C  CCT . AV0 E 3 .   ? 105.446 137.856 118.706 1.00 151.57 ? 803 AV0 A CCT 1 
HETATM 4767 C  CCU . AV0 E 3 .   ? 111.620 135.602 114.183 1.00 149.07 ? 803 AV0 A CCU 1 
HETATM 4768 C  CCV . AV0 E 3 .   ? 106.658 136.975 118.408 1.00 150.44 ? 803 AV0 A CCV 1 
HETATM 4769 C  CCW . AV0 E 3 .   ? 112.333 136.847 113.659 1.00 148.57 ? 803 AV0 A CCW 1 
HETATM 4770 ZN ZN  . ZN  F 2 .   ? 121.294 117.082 86.506  1.00 203.49 ? 804 ZN  A ZN  1 
HETATM 4771 ZN ZN  . ZN  G 2 .   ? 127.794 132.732 86.616  1.00 195.21 ? 501 ZN  B ZN  1 
HETATM 4772 ZN ZN  . ZN  H 2 .   ? 136.677 107.811 127.854 1.00 187.87 ? 502 ZN  B ZN  1 
HETATM 4773 ZN ZN  . ZN  I 2 .   ? 120.305 109.316 87.182  1.00 258.52 ? 503 ZN  B ZN  1 
HETATM 4774 C  C1  . AV0 J 3 .   ? 138.024 108.407 120.452 1.00 147.96 ? 504 AV0 B C1  1 
HETATM 4775 O  O1  . AV0 J 3 .   ? 136.945 107.753 119.902 1.00 146.26 ? 504 AV0 B O1  1 
HETATM 4776 C  C2  . AV0 J 3 .   ? 139.279 108.036 119.666 1.00 148.91 ? 504 AV0 B C2  1 
HETATM 4777 O  O2  . AV0 J 3 .   ? 139.722 106.742 119.975 1.00 153.05 ? 504 AV0 B O2  1 
HETATM 4778 C  C3  . AV0 J 3 .   ? 140.427 108.943 120.059 1.00 143.92 ? 504 AV0 B C3  1 
HETATM 4779 O  O3  . AV0 J 3 .   ? 141.563 108.692 119.268 1.00 142.14 ? 504 AV0 B O3  1 
HETATM 4780 C  C4  . AV0 J 3 .   ? 140.042 110.407 119.915 1.00 145.48 ? 504 AV0 B C4  1 
HETATM 4781 O  O4  . AV0 J 3 .   ? 141.175 111.133 120.334 1.00 151.28 ? 504 AV0 B O4  1 
HETATM 4782 C  C5  . AV0 J 3 .   ? 138.808 110.627 120.805 1.00 145.91 ? 504 AV0 B C5  1 
HETATM 4783 O  O5  . AV0 J 3 .   ? 137.772 109.782 120.349 1.00 145.97 ? 504 AV0 B O5  1 
HETATM 4784 C  C6  . AV0 J 3 .   ? 138.249 112.030 120.758 1.00 147.54 ? 504 AV0 B C6  1 
HETATM 4785 O  O6  . AV0 J 3 .   ? 136.843 111.932 120.750 1.00 149.84 ? 504 AV0 B O6  1 
HETATM 4786 C  CAA . AV0 J 3 .   ? 134.272 97.086  126.031 1.00 142.33 ? 504 AV0 B CAA 1 
HETATM 4787 C  CAB . AV0 J 3 .   ? 134.083 94.793  121.773 1.00 146.66 ? 504 AV0 B CAB 1 
HETATM 4788 O  OAI . AV0 J 3 .   ? 145.561 112.406 122.298 1.00 150.47 ? 504 AV0 B OAI 1 
HETATM 4789 O  OAJ . AV0 J 3 .   ? 132.825 114.466 114.769 1.00 149.71 ? 504 AV0 B OAJ 1 
HETATM 4790 O  OAL . AV0 J 3 .   ? 138.249 110.617 116.147 1.00 156.09 ? 504 AV0 B OAL 1 
HETATM 4791 O  OAN . AV0 J 3 .   ? 133.546 111.394 117.072 1.00 146.30 ? 504 AV0 B OAN 1 
HETATM 4792 O  OAP . AV0 J 3 .   ? 132.423 108.756 117.136 1.00 146.42 ? 504 AV0 B OAP 1 
HETATM 4793 O  OAQ . AV0 J 3 .   ? 145.450 110.952 120.215 1.00 147.13 ? 504 AV0 B OAQ 1 
HETATM 4794 O  OAR . AV0 J 3 .   ? 136.919 115.646 114.865 1.00 146.82 ? 504 AV0 B OAR 1 
HETATM 4795 O  OAS . AV0 J 3 .   ? 144.348 110.936 117.562 1.00 147.33 ? 504 AV0 B OAS 1 
HETATM 4796 O  OAT . AV0 J 3 .   ? 138.306 113.800 113.161 1.00 148.38 ? 504 AV0 B OAT 1 
HETATM 4797 O  OAU . AV0 J 3 .   ? 141.534 111.511 117.385 1.00 147.08 ? 504 AV0 B OAU 1 
HETATM 4798 O  OAV . AV0 J 3 .   ? 137.492 111.043 113.425 1.00 149.00 ? 504 AV0 B OAV 1 
HETATM 4799 C  CAW . AV0 J 3 .   ? 134.460 98.540  126.439 1.00 144.05 ? 504 AV0 B CAW 1 
HETATM 4800 C  CAX . AV0 J 3 .   ? 133.310 96.103  121.713 1.00 145.64 ? 504 AV0 B CAX 1 
HETATM 4801 C  CAY . AV0 J 3 .   ? 134.254 99.513  125.288 1.00 142.63 ? 504 AV0 B CAY 1 
HETATM 4802 C  CAZ . AV0 J 3 .   ? 134.076 97.198  120.984 1.00 141.83 ? 504 AV0 B CAZ 1 
HETATM 4803 C  CBA . AV0 J 3 .   ? 134.478 100.964 125.685 1.00 141.00 ? 504 AV0 B CBA 1 
HETATM 4804 C  CBB . AV0 J 3 .   ? 133.314 98.511  120.888 1.00 141.58 ? 504 AV0 B CBB 1 
HETATM 4805 C  CBC . AV0 J 3 .   ? 134.451 101.919 124.500 1.00 141.52 ? 504 AV0 B CBC 1 
HETATM 4806 C  CBD . AV0 J 3 .   ? 134.083 99.571  120.114 1.00 142.96 ? 504 AV0 B CBD 1 
HETATM 4807 C  CBE . AV0 J 3 .   ? 135.487 103.027 124.612 1.00 141.50 ? 504 AV0 B CBE 1 
HETATM 4808 C  CBF . AV0 J 3 .   ? 133.329 100.882 119.959 1.00 142.55 ? 504 AV0 B CBF 1 
HETATM 4809 C  CBG . AV0 J 3 .   ? 134.898 104.369 125.017 1.00 140.04 ? 504 AV0 B CBG 1 
HETATM 4810 C  CBH . AV0 J 3 .   ? 134.052 101.853 119.040 1.00 143.51 ? 504 AV0 B CBH 1 
HETATM 4811 C  CBI . AV0 J 3 .   ? 134.232 105.093 123.859 1.00 142.17 ? 504 AV0 B CBI 1 
HETATM 4812 C  CBJ . AV0 J 3 .   ? 133.232 103.086 118.694 1.00 141.66 ? 504 AV0 B CBJ 1 
HETATM 4813 C  CBK . AV0 J 3 .   ? 135.168 105.327 122.681 1.00 141.59 ? 504 AV0 B CBK 1 
HETATM 4814 C  CBL . AV0 J 3 .   ? 133.483 104.250 119.642 1.00 141.98 ? 504 AV0 B CBL 1 
HETATM 4815 C  CBM . AV0 J 3 .   ? 144.390 113.097 121.933 1.00 147.89 ? 504 AV0 B CBM 1 
HETATM 4816 C  CBN . AV0 J 3 .   ? 134.032 115.117 115.084 1.00 148.34 ? 504 AV0 B CBN 1 
HETATM 4817 C  CBP . AV0 J 3 .   ? 137.875 109.259 116.143 1.00 150.66 ? 504 AV0 B CBP 1 
HETATM 4818 C  CBQ . AV0 J 3 .   ? 134.493 106.146 121.589 1.00 142.98 ? 504 AV0 B CBQ 1 
HETATM 4819 C  CBR . AV0 J 3 .   ? 134.908 104.785 119.548 1.00 141.81 ? 504 AV0 B CBR 1 
HETATM 4820 C  CBS . AV0 J 3 .   ? 136.662 106.442 120.350 1.00 143.22 ? 504 AV0 B CBS 1 
HETATM 4821 C  CBT . AV0 J 3 .   ? 134.597 107.277 119.342 1.00 147.12 ? 504 AV0 B CBT 1 
HETATM 4822 O  OBV . AV0 J 3 .   ? 134.460 106.846 118.001 1.00 148.42 ? 504 AV0 B OBV 1 
HETATM 4823 O  OBX . AV0 J 3 .   ? 136.012 108.135 117.030 1.00 144.41 ? 504 AV0 B OBX 1 
HETATM 4824 O  OBY . AV0 J 3 .   ? 142.474 112.992 120.556 1.00 152.80 ? 504 AV0 B OBY 1 
HETATM 4825 O  OBZ . AV0 J 3 .   ? 134.598 112.876 114.603 1.00 152.31 ? 504 AV0 B OBZ 1 
HETATM 4826 O  OCB . AV0 J 3 .   ? 136.027 111.574 115.844 1.00 156.10 ? 504 AV0 B OCB 1 
HETATM 4827 C  CCC . AV0 J 3 .   ? 143.605 112.236 120.967 1.00 151.62 ? 504 AV0 B CCC 1 
HETATM 4828 C  CCD . AV0 J 3 .   ? 135.145 114.091 115.096 1.00 150.79 ? 504 AV0 B CCD 1 
HETATM 4829 C  CCF . AV0 J 3 .   ? 136.366 109.168 116.138 1.00 148.44 ? 504 AV0 B CCF 1 
HETATM 4830 C  CCH . AV0 J 3 .   ? 134.173 110.235 116.577 1.00 147.91 ? 504 AV0 B CCH 1 
HETATM 4831 C  CCJ . AV0 J 3 .   ? 134.648 107.808 117.037 1.00 147.70 ? 504 AV0 B CCJ 1 
HETATM 4832 C  CCL . AV0 J 3 .   ? 133.780 109.015 117.397 1.00 148.52 ? 504 AV0 B CCL 1 
HETATM 4833 C  CCM . AV0 J 3 .   ? 135.166 106.153 120.204 1.00 143.09 ? 504 AV0 B CCM 1 
HETATM 4834 C  CCN . AV0 J 3 .   ? 144.440 111.816 119.755 1.00 149.87 ? 504 AV0 B CCN 1 
HETATM 4835 C  CCO . AV0 J 3 .   ? 136.336 114.528 114.241 1.00 149.43 ? 504 AV0 B CCO 1 
HETATM 4836 C  CCQ . AV0 J 3 .   ? 135.682 110.450 116.626 1.00 149.94 ? 504 AV0 B CCQ 1 
HETATM 4837 C  CCR . AV0 J 3 .   ? 141.601 112.319 119.711 1.00 151.45 ? 504 AV0 B CCR 1 
HETATM 4838 C  CCS . AV0 J 3 .   ? 135.476 111.798 114.575 1.00 150.80 ? 504 AV0 B CCS 1 
HETATM 4839 C  CCT . AV0 J 3 .   ? 143.558 111.143 118.710 1.00 151.95 ? 504 AV0 B CCT 1 
HETATM 4840 C  CCU . AV0 J 3 .   ? 137.331 113.382 114.087 1.00 148.71 ? 504 AV0 B CCU 1 
HETATM 4841 C  CCV . AV0 J 3 .   ? 142.346 112.022 118.408 1.00 150.74 ? 504 AV0 B CCV 1 
HETATM 4842 C  CCW . AV0 J 3 .   ? 136.615 112.120 113.612 1.00 148.50 ? 504 AV0 B CCW 1 
# 
