data_9JHX
# 
_entry.id   9JHX 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JHX         pdb_00009jhx 10.2210/pdb9jhx/pdb 
WWPDB D_1300051395 ?            ?                   
EMDB  EMD-61491    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JHX 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Versatile Aromatic Prenyltransferase auraA mutant-Y207A in complex with DMSPP' 
_pdbx_database_related.db_id          EMD-61491 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dehaili119@163.com 
_pdbx_contact_author.name_first         Deha 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7191-2002 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, D.'    1 ? 
'Zhang, Y.' 2 ? 
'Wang, W.'  3 ? 
'Wang, P.'  4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                144 
_citation.page_last                 144 
_citation.title                     
'Characterization and structural analysis of a versatile aromatic prenyltransferase for imidazole-containing diketopiperazines.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55537-8 
_citation.pdbx_database_id_PubMed   39747040 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wang, W.'  1  0000-0002-3469-1765 
primary 'Wang, P.'  2  0000-0002-4983-9953 
primary 'Ma, C.'    3  ?                   
primary 'Li, K.'    4  ?                   
primary 'Wang, Z.'  5  ?                   
primary 'Liu, Y.'   6  ?                   
primary 'Wang, L.'  7  ?                   
primary 'Zhang, G.' 8  ?                   
primary 'Che, Q.'   9  ?                   
primary 'Zhu, T.'   10 ?                   
primary 'Zhang, Y.' 11 0000-0002-2017-1005 
primary 'Li, D.'    12 0000-0002-7191-2002 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Versatile Aromatic Prenyltransferase auraA' 48883.469 4 ? Y207A ? ? 
2 non-polymer syn 'DIMETHYLALLYL S-THIOLODIPHOSPHATE'          262.158   4 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MTVEHAQLTSNDLLVKSISSSPSPSPWDFLGRVLQFQHGDHKRWWDVLAPVFGISMASIGYKLDVQYRHLLVLYDAVIPN
MGPFPNSNASNITWTSPFPPGPLEASVNYQAGESSMFRFTIEPVGPHAGTPADPVNELAAKQLMQRLGQLQPGGVDSTMF
DHFYPLLCVDGPEARRQWDSIAHIYHKCHTVTALDMQRSAACTLKTAFPPLLRSTIMNTSMVDIMFDAVESFRKQSGLYF
DYTKIKEFMSEEKTHETMMVDRSYLSFDCLDPAKSRIKIYTEAKVKTLEEAYSFWSLGGRLSGPEIDYGFKIVSQMWDAI
YSKELPGGKQRENNHIQINWEMSAKDSSVAPKLYLTVIEDYDAYVSSAIVDLFTGLGWAAHVQTHKKIEKEAYPMCDANP
QSTHAYVWISLAYKKTGPYITVYTNPGASILEKA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MTVEHAQLTSNDLLVKSISSSPSPSPWDFLGRVLQFQHGDHKRWWDVLAPVFGISMASIGYKLDVQYRHLLVLYDAVIPN
MGPFPNSNASNITWTSPFPPGPLEASVNYQAGESSMFRFTIEPVGPHAGTPADPVNELAAKQLMQRLGQLQPGGVDSTMF
DHFYPLLCVDGPEARRQWDSIAHIYHKCHTVTALDMQRSAACTLKTAFPPLLRSTIMNTSMVDIMFDAVESFRKQSGLYF
DYTKIKEFMSEEKTHETMMVDRSYLSFDCLDPAKSRIKIYTEAKVKTLEEAYSFWSLGGRLSGPEIDYGFKIVSQMWDAI
YSKELPGGKQRENNHIQINWEMSAKDSSVAPKLYLTVIEDYDAYVSSAIVDLFTGLGWAAHVQTHKKIEKEAYPMCDANP
QSTHAYVWISLAYKKTGPYITVYTNPGASILEKA
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'DIMETHYLALLYL S-THIOLODIPHOSPHATE' 
_pdbx_entity_nonpoly.comp_id     DST 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   VAL n 
1 4   GLU n 
1 5   HIS n 
1 6   ALA n 
1 7   GLN n 
1 8   LEU n 
1 9   THR n 
1 10  SER n 
1 11  ASN n 
1 12  ASP n 
1 13  LEU n 
1 14  LEU n 
1 15  VAL n 
1 16  LYS n 
1 17  SER n 
1 18  ILE n 
1 19  SER n 
1 20  SER n 
1 21  SER n 
1 22  PRO n 
1 23  SER n 
1 24  PRO n 
1 25  SER n 
1 26  PRO n 
1 27  TRP n 
1 28  ASP n 
1 29  PHE n 
1 30  LEU n 
1 31  GLY n 
1 32  ARG n 
1 33  VAL n 
1 34  LEU n 
1 35  GLN n 
1 36  PHE n 
1 37  GLN n 
1 38  HIS n 
1 39  GLY n 
1 40  ASP n 
1 41  HIS n 
1 42  LYS n 
1 43  ARG n 
1 44  TRP n 
1 45  TRP n 
1 46  ASP n 
1 47  VAL n 
1 48  LEU n 
1 49  ALA n 
1 50  PRO n 
1 51  VAL n 
1 52  PHE n 
1 53  GLY n 
1 54  ILE n 
1 55  SER n 
1 56  MET n 
1 57  ALA n 
1 58  SER n 
1 59  ILE n 
1 60  GLY n 
1 61  TYR n 
1 62  LYS n 
1 63  LEU n 
1 64  ASP n 
1 65  VAL n 
1 66  GLN n 
1 67  TYR n 
1 68  ARG n 
1 69  HIS n 
1 70  LEU n 
1 71  LEU n 
1 72  VAL n 
1 73  LEU n 
1 74  TYR n 
1 75  ASP n 
1 76  ALA n 
1 77  VAL n 
1 78  ILE n 
1 79  PRO n 
1 80  ASN n 
1 81  MET n 
1 82  GLY n 
1 83  PRO n 
1 84  PHE n 
1 85  PRO n 
1 86  ASN n 
1 87  SER n 
1 88  ASN n 
1 89  ALA n 
1 90  SER n 
1 91  ASN n 
1 92  ILE n 
1 93  THR n 
1 94  TRP n 
1 95  THR n 
1 96  SER n 
1 97  PRO n 
1 98  PHE n 
1 99  PRO n 
1 100 PRO n 
1 101 GLY n 
1 102 PRO n 
1 103 LEU n 
1 104 GLU n 
1 105 ALA n 
1 106 SER n 
1 107 VAL n 
1 108 ASN n 
1 109 TYR n 
1 110 GLN n 
1 111 ALA n 
1 112 GLY n 
1 113 GLU n 
1 114 SER n 
1 115 SER n 
1 116 MET n 
1 117 PHE n 
1 118 ARG n 
1 119 PHE n 
1 120 THR n 
1 121 ILE n 
1 122 GLU n 
1 123 PRO n 
1 124 VAL n 
1 125 GLY n 
1 126 PRO n 
1 127 HIS n 
1 128 ALA n 
1 129 GLY n 
1 130 THR n 
1 131 PRO n 
1 132 ALA n 
1 133 ASP n 
1 134 PRO n 
1 135 VAL n 
1 136 ASN n 
1 137 GLU n 
1 138 LEU n 
1 139 ALA n 
1 140 ALA n 
1 141 LYS n 
1 142 GLN n 
1 143 LEU n 
1 144 MET n 
1 145 GLN n 
1 146 ARG n 
1 147 LEU n 
1 148 GLY n 
1 149 GLN n 
1 150 LEU n 
1 151 GLN n 
1 152 PRO n 
1 153 GLY n 
1 154 GLY n 
1 155 VAL n 
1 156 ASP n 
1 157 SER n 
1 158 THR n 
1 159 MET n 
1 160 PHE n 
1 161 ASP n 
1 162 HIS n 
1 163 PHE n 
1 164 TYR n 
1 165 PRO n 
1 166 LEU n 
1 167 LEU n 
1 168 CYS n 
1 169 VAL n 
1 170 ASP n 
1 171 GLY n 
1 172 PRO n 
1 173 GLU n 
1 174 ALA n 
1 175 ARG n 
1 176 ARG n 
1 177 GLN n 
1 178 TRP n 
1 179 ASP n 
1 180 SER n 
1 181 ILE n 
1 182 ALA n 
1 183 HIS n 
1 184 ILE n 
1 185 TYR n 
1 186 HIS n 
1 187 LYS n 
1 188 CYS n 
1 189 HIS n 
1 190 THR n 
1 191 VAL n 
1 192 THR n 
1 193 ALA n 
1 194 LEU n 
1 195 ASP n 
1 196 MET n 
1 197 GLN n 
1 198 ARG n 
1 199 SER n 
1 200 ALA n 
1 201 ALA n 
1 202 CYS n 
1 203 THR n 
1 204 LEU n 
1 205 LYS n 
1 206 THR n 
1 207 ALA n 
1 208 PHE n 
1 209 PRO n 
1 210 PRO n 
1 211 LEU n 
1 212 LEU n 
1 213 ARG n 
1 214 SER n 
1 215 THR n 
1 216 ILE n 
1 217 MET n 
1 218 ASN n 
1 219 THR n 
1 220 SER n 
1 221 MET n 
1 222 VAL n 
1 223 ASP n 
1 224 ILE n 
1 225 MET n 
1 226 PHE n 
1 227 ASP n 
1 228 ALA n 
1 229 VAL n 
1 230 GLU n 
1 231 SER n 
1 232 PHE n 
1 233 ARG n 
1 234 LYS n 
1 235 GLN n 
1 236 SER n 
1 237 GLY n 
1 238 LEU n 
1 239 TYR n 
1 240 PHE n 
1 241 ASP n 
1 242 TYR n 
1 243 THR n 
1 244 LYS n 
1 245 ILE n 
1 246 LYS n 
1 247 GLU n 
1 248 PHE n 
1 249 MET n 
1 250 SER n 
1 251 GLU n 
1 252 GLU n 
1 253 LYS n 
1 254 THR n 
1 255 HIS n 
1 256 GLU n 
1 257 THR n 
1 258 MET n 
1 259 MET n 
1 260 VAL n 
1 261 ASP n 
1 262 ARG n 
1 263 SER n 
1 264 TYR n 
1 265 LEU n 
1 266 SER n 
1 267 PHE n 
1 268 ASP n 
1 269 CYS n 
1 270 LEU n 
1 271 ASP n 
1 272 PRO n 
1 273 ALA n 
1 274 LYS n 
1 275 SER n 
1 276 ARG n 
1 277 ILE n 
1 278 LYS n 
1 279 ILE n 
1 280 TYR n 
1 281 THR n 
1 282 GLU n 
1 283 ALA n 
1 284 LYS n 
1 285 VAL n 
1 286 LYS n 
1 287 THR n 
1 288 LEU n 
1 289 GLU n 
1 290 GLU n 
1 291 ALA n 
1 292 TYR n 
1 293 SER n 
1 294 PHE n 
1 295 TRP n 
1 296 SER n 
1 297 LEU n 
1 298 GLY n 
1 299 GLY n 
1 300 ARG n 
1 301 LEU n 
1 302 SER n 
1 303 GLY n 
1 304 PRO n 
1 305 GLU n 
1 306 ILE n 
1 307 ASP n 
1 308 TYR n 
1 309 GLY n 
1 310 PHE n 
1 311 LYS n 
1 312 ILE n 
1 313 VAL n 
1 314 SER n 
1 315 GLN n 
1 316 MET n 
1 317 TRP n 
1 318 ASP n 
1 319 ALA n 
1 320 ILE n 
1 321 TYR n 
1 322 SER n 
1 323 LYS n 
1 324 GLU n 
1 325 LEU n 
1 326 PRO n 
1 327 GLY n 
1 328 GLY n 
1 329 LYS n 
1 330 GLN n 
1 331 ARG n 
1 332 GLU n 
1 333 ASN n 
1 334 ASN n 
1 335 HIS n 
1 336 ILE n 
1 337 GLN n 
1 338 ILE n 
1 339 ASN n 
1 340 TRP n 
1 341 GLU n 
1 342 MET n 
1 343 SER n 
1 344 ALA n 
1 345 LYS n 
1 346 ASP n 
1 347 SER n 
1 348 SER n 
1 349 VAL n 
1 350 ALA n 
1 351 PRO n 
1 352 LYS n 
1 353 LEU n 
1 354 TYR n 
1 355 LEU n 
1 356 THR n 
1 357 VAL n 
1 358 ILE n 
1 359 GLU n 
1 360 ASP n 
1 361 TYR n 
1 362 ASP n 
1 363 ALA n 
1 364 TYR n 
1 365 VAL n 
1 366 SER n 
1 367 SER n 
1 368 ALA n 
1 369 ILE n 
1 370 VAL n 
1 371 ASP n 
1 372 LEU n 
1 373 PHE n 
1 374 THR n 
1 375 GLY n 
1 376 LEU n 
1 377 GLY n 
1 378 TRP n 
1 379 ALA n 
1 380 ALA n 
1 381 HIS n 
1 382 VAL n 
1 383 GLN n 
1 384 THR n 
1 385 HIS n 
1 386 LYS n 
1 387 LYS n 
1 388 ILE n 
1 389 GLU n 
1 390 LYS n 
1 391 GLU n 
1 392 ALA n 
1 393 TYR n 
1 394 PRO n 
1 395 MET n 
1 396 CYS n 
1 397 ASP n 
1 398 ALA n 
1 399 ASN n 
1 400 PRO n 
1 401 GLN n 
1 402 SER n 
1 403 THR n 
1 404 HIS n 
1 405 ALA n 
1 406 TYR n 
1 407 VAL n 
1 408 TRP n 
1 409 ILE n 
1 410 SER n 
1 411 LEU n 
1 412 ALA n 
1 413 TYR n 
1 414 LYS n 
1 415 LYS n 
1 416 THR n 
1 417 GLY n 
1 418 PRO n 
1 419 TYR n 
1 420 ILE n 
1 421 THR n 
1 422 VAL n 
1 423 TYR n 
1 424 THR n 
1 425 ASN n 
1 426 PRO n 
1 427 GLY n 
1 428 ALA n 
1 429 SER n 
1 430 ILE n 
1 431 LEU n 
1 432 GLU n 
1 433 LYS n 
1 434 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   434 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Penicillium solitum' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     60172 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                             ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                            ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                          ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                     ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                            ? 'C3 H7 N O2 S'   121.158 
DST non-polymer         . 'DIMETHYLALLYL S-THIOLODIPHOSPHATE' 
'DMASPP; DMAPP; DMADP; Dimethylallyl pyrophosphate; dimethylallyl diphosphate; isoprenyl pyrophosphate' 'C5 H12 O6 P2 S' 262.158 
GLN 'L-peptide linking' y GLUTAMINE                           ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                     ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                             ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                           ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                          ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                             ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                              ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                          ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                       ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                             ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                              ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                           ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                          ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                            ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                              ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   VAL 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   HIS 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   GLN 7   7   ?   ?   ?   A . n 
A 1 8   LEU 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  SER 10  10  ?   ?   ?   A . n 
A 1 11  ASN 11  11  ?   ?   ?   A . n 
A 1 12  ASP 12  12  ?   ?   ?   A . n 
A 1 13  LEU 13  13  ?   ?   ?   A . n 
A 1 14  LEU 14  14  ?   ?   ?   A . n 
A 1 15  VAL 15  15  ?   ?   ?   A . n 
A 1 16  LYS 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  ILE 18  18  ?   ?   ?   A . n 
A 1 19  SER 19  19  ?   ?   ?   A . n 
A 1 20  SER 20  20  ?   ?   ?   A . n 
A 1 21  SER 21  21  ?   ?   ?   A . n 
A 1 22  PRO 22  22  ?   ?   ?   A . n 
A 1 23  SER 23  23  23  SER SER A . n 
A 1 24  PRO 24  24  24  PRO PRO A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  PRO 26  26  26  PRO PRO A . n 
A 1 27  TRP 27  27  27  TRP TRP A . n 
A 1 28  ASP 28  28  28  ASP ASP A . n 
A 1 29  PHE 29  29  29  PHE PHE A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  ARG 32  32  32  ARG ARG A . n 
A 1 33  VAL 33  33  33  VAL VAL A . n 
A 1 34  LEU 34  34  34  LEU LEU A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  HIS 38  38  38  HIS HIS A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  ASP 40  40  40  ASP ASP A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  LYS 42  42  42  LYS LYS A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  TRP 44  44  44  TRP TRP A . n 
A 1 45  TRP 45  45  45  TRP TRP A . n 
A 1 46  ASP 46  46  46  ASP ASP A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  PRO 50  50  50  PRO PRO A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  SER 55  55  55  SER SER A . n 
A 1 56  MET 56  56  56  MET MET A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  TYR 61  61  61  TYR TYR A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  ASP 64  64  64  ASP ASP A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  GLN 66  66  66  GLN GLN A . n 
A 1 67  TYR 67  67  67  TYR TYR A . n 
A 1 68  ARG 68  68  68  ARG ARG A . n 
A 1 69  HIS 69  69  69  HIS HIS A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  ASP 75  75  75  ASP ASP A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  ILE 78  78  78  ILE ILE A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  ASN 80  80  80  ASN ASN A . n 
A 1 81  MET 81  81  81  MET MET A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  SER 87  87  87  SER SER A . n 
A 1 88  ASN 88  88  88  ASN ASN A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  ASN 91  91  91  ASN ASN A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  THR 95  95  95  THR THR A . n 
A 1 96  SER 96  96  96  SER SER A . n 
A 1 97  PRO 97  97  97  PRO PRO A . n 
A 1 98  PHE 98  98  98  PHE PHE A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 VAL 107 107 107 VAL VAL A . n 
A 1 108 ASN 108 108 108 ASN ASN A . n 
A 1 109 TYR 109 109 109 TYR TYR A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 MET 116 116 116 MET MET A . n 
A 1 117 PHE 117 117 117 PHE PHE A . n 
A 1 118 ARG 118 118 118 ARG ARG A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 GLU 122 122 122 GLU GLU A . n 
A 1 123 PRO 123 123 123 PRO PRO A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 GLY 125 125 125 GLY GLY A . n 
A 1 126 PRO 126 126 126 PRO PRO A . n 
A 1 127 HIS 127 127 127 HIS HIS A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 PRO 131 131 131 PRO PRO A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 ASP 133 133 133 ASP ASP A . n 
A 1 134 PRO 134 134 134 PRO PRO A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 ASN 136 136 136 ASN ASN A . n 
A 1 137 GLU 137 137 137 GLU GLU A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 ALA 139 139 139 ALA ALA A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 LYS 141 141 141 LYS LYS A . n 
A 1 142 GLN 142 142 142 GLN GLN A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 MET 144 144 144 MET MET A . n 
A 1 145 GLN 145 145 145 GLN GLN A . n 
A 1 146 ARG 146 146 146 ARG ARG A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 GLN 149 149 149 GLN GLN A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 GLN 151 151 151 GLN GLN A . n 
A 1 152 PRO 152 152 152 PRO PRO A . n 
A 1 153 GLY 153 153 153 GLY GLY A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 ASP 156 156 156 ASP ASP A . n 
A 1 157 SER 157 157 157 SER SER A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 MET 159 159 159 MET MET A . n 
A 1 160 PHE 160 160 160 PHE PHE A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 HIS 162 162 162 HIS HIS A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 TYR 164 164 164 TYR TYR A . n 
A 1 165 PRO 165 165 165 PRO PRO A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 CYS 168 168 168 CYS CYS A . n 
A 1 169 VAL 169 169 169 VAL VAL A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 PRO 172 172 172 PRO PRO A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 ARG 176 176 176 ARG ARG A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 TRP 178 178 178 TRP TRP A . n 
A 1 179 ASP 179 179 179 ASP ASP A . n 
A 1 180 SER 180 180 180 SER SER A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 TYR 185 185 185 TYR TYR A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 LYS 187 187 187 LYS LYS A . n 
A 1 188 CYS 188 188 188 CYS CYS A . n 
A 1 189 HIS 189 189 189 HIS HIS A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 ASP 195 195 195 ASP ASP A . n 
A 1 196 MET 196 196 196 MET MET A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 SER 199 199 199 SER SER A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 ALA 201 201 201 ALA ALA A . n 
A 1 202 CYS 202 202 202 CYS CYS A . n 
A 1 203 THR 203 203 203 THR THR A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 LYS 205 205 205 LYS LYS A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 PHE 208 208 208 PHE PHE A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 THR 215 215 215 THR THR A . n 
A 1 216 ILE 216 216 216 ILE ILE A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 ASN 218 218 218 ASN ASN A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 MET 221 221 221 MET MET A . n 
A 1 222 VAL 222 222 222 VAL VAL A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 ILE 224 224 224 ILE ILE A . n 
A 1 225 MET 225 225 225 MET MET A . n 
A 1 226 PHE 226 226 226 PHE PHE A . n 
A 1 227 ASP 227 227 227 ASP ASP A . n 
A 1 228 ALA 228 228 228 ALA ALA A . n 
A 1 229 VAL 229 229 229 VAL VAL A . n 
A 1 230 GLU 230 230 230 GLU GLU A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 ARG 233 233 233 ARG ARG A . n 
A 1 234 LYS 234 234 234 LYS LYS A . n 
A 1 235 GLN 235 235 235 GLN GLN A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 GLY 237 237 237 GLY GLY A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 ASP 241 241 241 ASP ASP A . n 
A 1 242 TYR 242 242 242 TYR TYR A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 LYS 244 244 244 LYS LYS A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 LYS 246 246 246 LYS LYS A . n 
A 1 247 GLU 247 247 247 GLU GLU A . n 
A 1 248 PHE 248 248 248 PHE PHE A . n 
A 1 249 MET 249 249 249 MET MET A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 GLU 251 251 251 GLU GLU A . n 
A 1 252 GLU 252 252 252 GLU GLU A . n 
A 1 253 LYS 253 253 253 LYS LYS A . n 
A 1 254 THR 254 254 254 THR THR A . n 
A 1 255 HIS 255 255 255 HIS HIS A . n 
A 1 256 GLU 256 256 256 GLU GLU A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 MET 258 258 258 MET MET A . n 
A 1 259 MET 259 259 259 MET MET A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 ASP 261 261 261 ASP ASP A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 TYR 264 264 264 TYR TYR A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 ASP 268 268 268 ASP ASP A . n 
A 1 269 CYS 269 269 269 CYS CYS A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 ASP 271 271 271 ASP ASP A . n 
A 1 272 PRO 272 272 272 PRO PRO A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 ILE 277 277 277 ILE ILE A . n 
A 1 278 LYS 278 278 278 LYS LYS A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 TYR 280 280 280 TYR TYR A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 GLU 282 282 282 GLU GLU A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 LYS 284 284 284 LYS LYS A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 LYS 286 286 286 LYS LYS A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 TYR 292 292 292 TYR TYR A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 PHE 294 294 294 PHE PHE A . n 
A 1 295 TRP 295 295 295 TRP TRP A . n 
A 1 296 SER 296 296 296 SER SER A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 SER 302 302 302 SER SER A . n 
A 1 303 GLY 303 303 303 GLY GLY A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 ILE 306 306 306 ILE ILE A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 TYR 308 308 308 TYR TYR A . n 
A 1 309 GLY 309 309 309 GLY GLY A . n 
A 1 310 PHE 310 310 310 PHE PHE A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 ILE 312 312 312 ILE ILE A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 GLN 315 315 315 GLN GLN A . n 
A 1 316 MET 316 316 316 MET MET A . n 
A 1 317 TRP 317 317 317 TRP TRP A . n 
A 1 318 ASP 318 318 318 ASP ASP A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 ILE 320 320 320 ILE ILE A . n 
A 1 321 TYR 321 321 321 TYR TYR A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 GLU 324 324 324 GLU GLU A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 GLY 327 327 327 GLY GLY A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 GLN 330 330 330 GLN GLN A . n 
A 1 331 ARG 331 331 331 ARG ARG A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 ASN 333 333 333 ASN ASN A . n 
A 1 334 ASN 334 334 334 ASN ASN A . n 
A 1 335 HIS 335 335 335 HIS HIS A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 GLN 337 337 337 GLN GLN A . n 
A 1 338 ILE 338 338 338 ILE ILE A . n 
A 1 339 ASN 339 339 339 ASN ASN A . n 
A 1 340 TRP 340 340 340 TRP TRP A . n 
A 1 341 GLU 341 341 341 GLU GLU A . n 
A 1 342 MET 342 342 342 MET MET A . n 
A 1 343 SER 343 343 343 SER SER A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 ASP 346 346 346 ASP ASP A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 SER 348 348 348 SER SER A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 PRO 351 351 351 PRO PRO A . n 
A 1 352 LYS 352 352 352 LYS LYS A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 TYR 354 354 354 TYR TYR A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 THR 356 356 356 THR THR A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ILE 358 358 358 ILE ILE A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 ASP 360 360 360 ASP ASP A . n 
A 1 361 TYR 361 361 361 TYR TYR A . n 
A 1 362 ASP 362 362 362 ASP ASP A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 TYR 364 364 364 TYR TYR A . n 
A 1 365 VAL 365 365 365 VAL VAL A . n 
A 1 366 SER 366 366 366 SER SER A . n 
A 1 367 SER 367 367 367 SER SER A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 ILE 369 369 369 ILE ILE A . n 
A 1 370 VAL 370 370 370 VAL VAL A . n 
A 1 371 ASP 371 371 371 ASP ASP A . n 
A 1 372 LEU 372 372 372 LEU LEU A . n 
A 1 373 PHE 373 373 373 PHE PHE A . n 
A 1 374 THR 374 374 374 THR THR A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 LEU 376 376 376 LEU LEU A . n 
A 1 377 GLY 377 377 377 GLY GLY A . n 
A 1 378 TRP 378 378 378 TRP TRP A . n 
A 1 379 ALA 379 379 379 ALA ALA A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 HIS 381 381 381 HIS HIS A . n 
A 1 382 VAL 382 382 382 VAL VAL A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 THR 384 384 384 THR THR A . n 
A 1 385 HIS 385 385 385 HIS HIS A . n 
A 1 386 LYS 386 386 386 LYS LYS A . n 
A 1 387 LYS 387 387 387 LYS LYS A . n 
A 1 388 ILE 388 388 388 ILE ILE A . n 
A 1 389 GLU 389 389 389 GLU GLU A . n 
A 1 390 LYS 390 390 390 LYS LYS A . n 
A 1 391 GLU 391 391 391 GLU GLU A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 PRO 394 394 394 PRO PRO A . n 
A 1 395 MET 395 395 395 MET MET A . n 
A 1 396 CYS 396 396 396 CYS CYS A . n 
A 1 397 ASP 397 397 397 ASP ASP A . n 
A 1 398 ALA 398 398 398 ALA ALA A . n 
A 1 399 ASN 399 399 399 ASN ASN A . n 
A 1 400 PRO 400 400 400 PRO PRO A . n 
A 1 401 GLN 401 401 401 GLN GLN A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 THR 403 403 403 THR THR A . n 
A 1 404 HIS 404 404 404 HIS HIS A . n 
A 1 405 ALA 405 405 405 ALA ALA A . n 
A 1 406 TYR 406 406 406 TYR TYR A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 TRP 408 408 408 TRP TRP A . n 
A 1 409 ILE 409 409 409 ILE ILE A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 ALA 412 412 412 ALA ALA A . n 
A 1 413 TYR 413 413 413 TYR TYR A . n 
A 1 414 LYS 414 414 414 LYS LYS A . n 
A 1 415 LYS 415 415 415 LYS LYS A . n 
A 1 416 THR 416 416 416 THR THR A . n 
A 1 417 GLY 417 417 417 GLY GLY A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 TYR 419 419 419 TYR TYR A . n 
A 1 420 ILE 420 420 420 ILE ILE A . n 
A 1 421 THR 421 421 421 THR THR A . n 
A 1 422 VAL 422 422 422 VAL VAL A . n 
A 1 423 TYR 423 423 423 TYR TYR A . n 
A 1 424 THR 424 424 424 THR THR A . n 
A 1 425 ASN 425 425 425 ASN ASN A . n 
A 1 426 PRO 426 426 426 PRO PRO A . n 
A 1 427 GLY 427 427 427 GLY GLY A . n 
A 1 428 ALA 428 428 428 ALA ALA A . n 
A 1 429 SER 429 429 429 SER SER A . n 
A 1 430 ILE 430 430 430 ILE ILE A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 GLU 432 432 432 GLU GLU A . n 
A 1 433 LYS 433 433 ?   ?   ?   A . n 
A 1 434 ALA 434 434 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   THR 2   2   ?   ?   ?   B . n 
B 1 3   VAL 3   3   ?   ?   ?   B . n 
B 1 4   GLU 4   4   ?   ?   ?   B . n 
B 1 5   HIS 5   5   ?   ?   ?   B . n 
B 1 6   ALA 6   6   ?   ?   ?   B . n 
B 1 7   GLN 7   7   ?   ?   ?   B . n 
B 1 8   LEU 8   8   ?   ?   ?   B . n 
B 1 9   THR 9   9   ?   ?   ?   B . n 
B 1 10  SER 10  10  ?   ?   ?   B . n 
B 1 11  ASN 11  11  ?   ?   ?   B . n 
B 1 12  ASP 12  12  ?   ?   ?   B . n 
B 1 13  LEU 13  13  ?   ?   ?   B . n 
B 1 14  LEU 14  14  ?   ?   ?   B . n 
B 1 15  VAL 15  15  ?   ?   ?   B . n 
B 1 16  LYS 16  16  ?   ?   ?   B . n 
B 1 17  SER 17  17  ?   ?   ?   B . n 
B 1 18  ILE 18  18  ?   ?   ?   B . n 
B 1 19  SER 19  19  ?   ?   ?   B . n 
B 1 20  SER 20  20  ?   ?   ?   B . n 
B 1 21  SER 21  21  ?   ?   ?   B . n 
B 1 22  PRO 22  22  ?   ?   ?   B . n 
B 1 23  SER 23  23  23  SER SER B . n 
B 1 24  PRO 24  24  24  PRO PRO B . n 
B 1 25  SER 25  25  25  SER SER B . n 
B 1 26  PRO 26  26  26  PRO PRO B . n 
B 1 27  TRP 27  27  27  TRP TRP B . n 
B 1 28  ASP 28  28  28  ASP ASP B . n 
B 1 29  PHE 29  29  29  PHE PHE B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  ARG 32  32  32  ARG ARG B . n 
B 1 33  VAL 33  33  33  VAL VAL B . n 
B 1 34  LEU 34  34  34  LEU LEU B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  PHE 36  36  36  PHE PHE B . n 
B 1 37  GLN 37  37  37  GLN GLN B . n 
B 1 38  HIS 38  38  38  HIS HIS B . n 
B 1 39  GLY 39  39  39  GLY GLY B . n 
B 1 40  ASP 40  40  40  ASP ASP B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  LYS 42  42  42  LYS LYS B . n 
B 1 43  ARG 43  43  43  ARG ARG B . n 
B 1 44  TRP 44  44  44  TRP TRP B . n 
B 1 45  TRP 45  45  45  TRP TRP B . n 
B 1 46  ASP 46  46  46  ASP ASP B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  PRO 50  50  50  PRO PRO B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  GLY 53  53  53  GLY GLY B . n 
B 1 54  ILE 54  54  54  ILE ILE B . n 
B 1 55  SER 55  55  55  SER SER B . n 
B 1 56  MET 56  56  56  MET MET B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  SER 58  58  58  SER SER B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  TYR 61  61  61  TYR TYR B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  LEU 63  63  63  LEU LEU B . n 
B 1 64  ASP 64  64  64  ASP ASP B . n 
B 1 65  VAL 65  65  65  VAL VAL B . n 
B 1 66  GLN 66  66  66  GLN GLN B . n 
B 1 67  TYR 67  67  67  TYR TYR B . n 
B 1 68  ARG 68  68  68  ARG ARG B . n 
B 1 69  HIS 69  69  69  HIS HIS B . n 
B 1 70  LEU 70  70  70  LEU LEU B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  TYR 74  74  74  TYR TYR B . n 
B 1 75  ASP 75  75  75  ASP ASP B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  ILE 78  78  78  ILE ILE B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  ASN 80  80  80  ASN ASN B . n 
B 1 81  MET 81  81  81  MET MET B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  PRO 83  83  83  PRO PRO B . n 
B 1 84  PHE 84  84  84  PHE PHE B . n 
B 1 85  PRO 85  85  85  PRO PRO B . n 
B 1 86  ASN 86  86  86  ASN ASN B . n 
B 1 87  SER 87  87  87  SER SER B . n 
B 1 88  ASN 88  88  88  ASN ASN B . n 
B 1 89  ALA 89  89  89  ALA ALA B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  ASN 91  91  91  ASN ASN B . n 
B 1 92  ILE 92  92  92  ILE ILE B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  TRP 94  94  94  TRP TRP B . n 
B 1 95  THR 95  95  95  THR THR B . n 
B 1 96  SER 96  96  96  SER SER B . n 
B 1 97  PRO 97  97  97  PRO PRO B . n 
B 1 98  PHE 98  98  98  PHE PHE B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 PRO 100 100 100 PRO PRO B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 PRO 102 102 102 PRO PRO B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 ALA 105 105 105 ALA ALA B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 VAL 107 107 107 VAL VAL B . n 
B 1 108 ASN 108 108 108 ASN ASN B . n 
B 1 109 TYR 109 109 109 TYR TYR B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 ALA 111 111 111 ALA ALA B . n 
B 1 112 GLY 112 112 112 GLY GLY B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 SER 114 114 114 SER SER B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 MET 116 116 116 MET MET B . n 
B 1 117 PHE 117 117 117 PHE PHE B . n 
B 1 118 ARG 118 118 118 ARG ARG B . n 
B 1 119 PHE 119 119 119 PHE PHE B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 ILE 121 121 121 ILE ILE B . n 
B 1 122 GLU 122 122 122 GLU GLU B . n 
B 1 123 PRO 123 123 123 PRO PRO B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 GLY 125 125 125 GLY GLY B . n 
B 1 126 PRO 126 126 126 PRO PRO B . n 
B 1 127 HIS 127 127 127 HIS HIS B . n 
B 1 128 ALA 128 128 128 ALA ALA B . n 
B 1 129 GLY 129 129 129 GLY GLY B . n 
B 1 130 THR 130 130 130 THR THR B . n 
B 1 131 PRO 131 131 131 PRO PRO B . n 
B 1 132 ALA 132 132 132 ALA ALA B . n 
B 1 133 ASP 133 133 133 ASP ASP B . n 
B 1 134 PRO 134 134 134 PRO PRO B . n 
B 1 135 VAL 135 135 135 VAL VAL B . n 
B 1 136 ASN 136 136 136 ASN ASN B . n 
B 1 137 GLU 137 137 137 GLU GLU B . n 
B 1 138 LEU 138 138 138 LEU LEU B . n 
B 1 139 ALA 139 139 139 ALA ALA B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 LYS 141 141 141 LYS LYS B . n 
B 1 142 GLN 142 142 142 GLN GLN B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 MET 144 144 144 MET MET B . n 
B 1 145 GLN 145 145 145 GLN GLN B . n 
B 1 146 ARG 146 146 146 ARG ARG B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 GLY 148 148 148 GLY GLY B . n 
B 1 149 GLN 149 149 149 GLN GLN B . n 
B 1 150 LEU 150 150 150 LEU LEU B . n 
B 1 151 GLN 151 151 151 GLN GLN B . n 
B 1 152 PRO 152 152 152 PRO PRO B . n 
B 1 153 GLY 153 153 153 GLY GLY B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 VAL 155 155 155 VAL VAL B . n 
B 1 156 ASP 156 156 156 ASP ASP B . n 
B 1 157 SER 157 157 157 SER SER B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 MET 159 159 159 MET MET B . n 
B 1 160 PHE 160 160 160 PHE PHE B . n 
B 1 161 ASP 161 161 161 ASP ASP B . n 
B 1 162 HIS 162 162 162 HIS HIS B . n 
B 1 163 PHE 163 163 163 PHE PHE B . n 
B 1 164 TYR 164 164 164 TYR TYR B . n 
B 1 165 PRO 165 165 165 PRO PRO B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 CYS 168 168 168 CYS CYS B . n 
B 1 169 VAL 169 169 169 VAL VAL B . n 
B 1 170 ASP 170 170 170 ASP ASP B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 PRO 172 172 172 PRO PRO B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 ARG 175 175 175 ARG ARG B . n 
B 1 176 ARG 176 176 176 ARG ARG B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 TRP 178 178 178 TRP TRP B . n 
B 1 179 ASP 179 179 179 ASP ASP B . n 
B 1 180 SER 180 180 180 SER SER B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 HIS 183 183 183 HIS HIS B . n 
B 1 184 ILE 184 184 184 ILE ILE B . n 
B 1 185 TYR 185 185 185 TYR TYR B . n 
B 1 186 HIS 186 186 186 HIS HIS B . n 
B 1 187 LYS 187 187 187 LYS LYS B . n 
B 1 188 CYS 188 188 188 CYS CYS B . n 
B 1 189 HIS 189 189 189 HIS HIS B . n 
B 1 190 THR 190 190 190 THR THR B . n 
B 1 191 VAL 191 191 191 VAL VAL B . n 
B 1 192 THR 192 192 192 THR THR B . n 
B 1 193 ALA 193 193 193 ALA ALA B . n 
B 1 194 LEU 194 194 194 LEU LEU B . n 
B 1 195 ASP 195 195 195 ASP ASP B . n 
B 1 196 MET 196 196 196 MET MET B . n 
B 1 197 GLN 197 197 197 GLN GLN B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 SER 199 199 199 SER SER B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 ALA 201 201 201 ALA ALA B . n 
B 1 202 CYS 202 202 202 CYS CYS B . n 
B 1 203 THR 203 203 203 THR THR B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 LYS 205 205 205 LYS LYS B . n 
B 1 206 THR 206 206 206 THR THR B . n 
B 1 207 ALA 207 207 207 ALA ALA B . n 
B 1 208 PHE 208 208 208 PHE PHE B . n 
B 1 209 PRO 209 209 209 PRO PRO B . n 
B 1 210 PRO 210 210 210 PRO PRO B . n 
B 1 211 LEU 211 211 211 LEU LEU B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 ARG 213 213 213 ARG ARG B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 THR 215 215 215 THR THR B . n 
B 1 216 ILE 216 216 216 ILE ILE B . n 
B 1 217 MET 217 217 217 MET MET B . n 
B 1 218 ASN 218 218 218 ASN ASN B . n 
B 1 219 THR 219 219 219 THR THR B . n 
B 1 220 SER 220 220 220 SER SER B . n 
B 1 221 MET 221 221 221 MET MET B . n 
B 1 222 VAL 222 222 222 VAL VAL B . n 
B 1 223 ASP 223 223 223 ASP ASP B . n 
B 1 224 ILE 224 224 224 ILE ILE B . n 
B 1 225 MET 225 225 225 MET MET B . n 
B 1 226 PHE 226 226 226 PHE PHE B . n 
B 1 227 ASP 227 227 227 ASP ASP B . n 
B 1 228 ALA 228 228 228 ALA ALA B . n 
B 1 229 VAL 229 229 229 VAL VAL B . n 
B 1 230 GLU 230 230 230 GLU GLU B . n 
B 1 231 SER 231 231 231 SER SER B . n 
B 1 232 PHE 232 232 232 PHE PHE B . n 
B 1 233 ARG 233 233 233 ARG ARG B . n 
B 1 234 LYS 234 234 234 LYS LYS B . n 
B 1 235 GLN 235 235 235 GLN GLN B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 GLY 237 237 237 GLY GLY B . n 
B 1 238 LEU 238 238 238 LEU LEU B . n 
B 1 239 TYR 239 239 239 TYR TYR B . n 
B 1 240 PHE 240 240 240 PHE PHE B . n 
B 1 241 ASP 241 241 241 ASP ASP B . n 
B 1 242 TYR 242 242 242 TYR TYR B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 LYS 244 244 244 LYS LYS B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 LYS 246 246 246 LYS LYS B . n 
B 1 247 GLU 247 247 247 GLU GLU B . n 
B 1 248 PHE 248 248 248 PHE PHE B . n 
B 1 249 MET 249 249 249 MET MET B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 GLU 251 251 251 GLU GLU B . n 
B 1 252 GLU 252 252 252 GLU GLU B . n 
B 1 253 LYS 253 253 253 LYS LYS B . n 
B 1 254 THR 254 254 254 THR THR B . n 
B 1 255 HIS 255 255 255 HIS HIS B . n 
B 1 256 GLU 256 256 256 GLU GLU B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 MET 258 258 258 MET MET B . n 
B 1 259 MET 259 259 259 MET MET B . n 
B 1 260 VAL 260 260 260 VAL VAL B . n 
B 1 261 ASP 261 261 261 ASP ASP B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 TYR 264 264 264 TYR TYR B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 SER 266 266 266 SER SER B . n 
B 1 267 PHE 267 267 267 PHE PHE B . n 
B 1 268 ASP 268 268 268 ASP ASP B . n 
B 1 269 CYS 269 269 269 CYS CYS B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 ASP 271 271 271 ASP ASP B . n 
B 1 272 PRO 272 272 272 PRO PRO B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 LYS 274 274 274 LYS LYS B . n 
B 1 275 SER 275 275 275 SER SER B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 ILE 277 277 277 ILE ILE B . n 
B 1 278 LYS 278 278 278 LYS LYS B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 TYR 280 280 280 TYR TYR B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 GLU 282 282 282 GLU GLU B . n 
B 1 283 ALA 283 283 283 ALA ALA B . n 
B 1 284 LYS 284 284 284 LYS LYS B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 LYS 286 286 286 LYS LYS B . n 
B 1 287 THR 287 287 287 THR THR B . n 
B 1 288 LEU 288 288 288 LEU LEU B . n 
B 1 289 GLU 289 289 289 GLU GLU B . n 
B 1 290 GLU 290 290 290 GLU GLU B . n 
B 1 291 ALA 291 291 291 ALA ALA B . n 
B 1 292 TYR 292 292 292 TYR TYR B . n 
B 1 293 SER 293 293 293 SER SER B . n 
B 1 294 PHE 294 294 294 PHE PHE B . n 
B 1 295 TRP 295 295 295 TRP TRP B . n 
B 1 296 SER 296 296 296 SER SER B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 GLY 298 298 298 GLY GLY B . n 
B 1 299 GLY 299 299 299 GLY GLY B . n 
B 1 300 ARG 300 300 300 ARG ARG B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 SER 302 302 302 SER SER B . n 
B 1 303 GLY 303 303 303 GLY GLY B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 ILE 306 306 306 ILE ILE B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 TYR 308 308 308 TYR TYR B . n 
B 1 309 GLY 309 309 309 GLY GLY B . n 
B 1 310 PHE 310 310 310 PHE PHE B . n 
B 1 311 LYS 311 311 311 LYS LYS B . n 
B 1 312 ILE 312 312 312 ILE ILE B . n 
B 1 313 VAL 313 313 313 VAL VAL B . n 
B 1 314 SER 314 314 314 SER SER B . n 
B 1 315 GLN 315 315 315 GLN GLN B . n 
B 1 316 MET 316 316 316 MET MET B . n 
B 1 317 TRP 317 317 317 TRP TRP B . n 
B 1 318 ASP 318 318 318 ASP ASP B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 ILE 320 320 320 ILE ILE B . n 
B 1 321 TYR 321 321 321 TYR TYR B . n 
B 1 322 SER 322 322 322 SER SER B . n 
B 1 323 LYS 323 323 323 LYS LYS B . n 
B 1 324 GLU 324 324 324 GLU GLU B . n 
B 1 325 LEU 325 325 325 LEU LEU B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 GLY 327 327 327 GLY GLY B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 LYS 329 329 329 LYS LYS B . n 
B 1 330 GLN 330 330 330 GLN GLN B . n 
B 1 331 ARG 331 331 331 ARG ARG B . n 
B 1 332 GLU 332 332 332 GLU GLU B . n 
B 1 333 ASN 333 333 333 ASN ASN B . n 
B 1 334 ASN 334 334 334 ASN ASN B . n 
B 1 335 HIS 335 335 335 HIS HIS B . n 
B 1 336 ILE 336 336 336 ILE ILE B . n 
B 1 337 GLN 337 337 337 GLN GLN B . n 
B 1 338 ILE 338 338 338 ILE ILE B . n 
B 1 339 ASN 339 339 339 ASN ASN B . n 
B 1 340 TRP 340 340 340 TRP TRP B . n 
B 1 341 GLU 341 341 341 GLU GLU B . n 
B 1 342 MET 342 342 342 MET MET B . n 
B 1 343 SER 343 343 343 SER SER B . n 
B 1 344 ALA 344 344 344 ALA ALA B . n 
B 1 345 LYS 345 345 345 LYS LYS B . n 
B 1 346 ASP 346 346 346 ASP ASP B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 SER 348 348 348 SER SER B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 PRO 351 351 351 PRO PRO B . n 
B 1 352 LYS 352 352 352 LYS LYS B . n 
B 1 353 LEU 353 353 353 LEU LEU B . n 
B 1 354 TYR 354 354 354 TYR TYR B . n 
B 1 355 LEU 355 355 355 LEU LEU B . n 
B 1 356 THR 356 356 356 THR THR B . n 
B 1 357 VAL 357 357 357 VAL VAL B . n 
B 1 358 ILE 358 358 358 ILE ILE B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 ASP 360 360 360 ASP ASP B . n 
B 1 361 TYR 361 361 361 TYR TYR B . n 
B 1 362 ASP 362 362 362 ASP ASP B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 TYR 364 364 364 TYR TYR B . n 
B 1 365 VAL 365 365 365 VAL VAL B . n 
B 1 366 SER 366 366 366 SER SER B . n 
B 1 367 SER 367 367 367 SER SER B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 ILE 369 369 369 ILE ILE B . n 
B 1 370 VAL 370 370 370 VAL VAL B . n 
B 1 371 ASP 371 371 371 ASP ASP B . n 
B 1 372 LEU 372 372 372 LEU LEU B . n 
B 1 373 PHE 373 373 373 PHE PHE B . n 
B 1 374 THR 374 374 374 THR THR B . n 
B 1 375 GLY 375 375 375 GLY GLY B . n 
B 1 376 LEU 376 376 376 LEU LEU B . n 
B 1 377 GLY 377 377 377 GLY GLY B . n 
B 1 378 TRP 378 378 378 TRP TRP B . n 
B 1 379 ALA 379 379 379 ALA ALA B . n 
B 1 380 ALA 380 380 380 ALA ALA B . n 
B 1 381 HIS 381 381 381 HIS HIS B . n 
B 1 382 VAL 382 382 382 VAL VAL B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 THR 384 384 384 THR THR B . n 
B 1 385 HIS 385 385 385 HIS HIS B . n 
B 1 386 LYS 386 386 386 LYS LYS B . n 
B 1 387 LYS 387 387 387 LYS LYS B . n 
B 1 388 ILE 388 388 388 ILE ILE B . n 
B 1 389 GLU 389 389 389 GLU GLU B . n 
B 1 390 LYS 390 390 390 LYS LYS B . n 
B 1 391 GLU 391 391 391 GLU GLU B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 PRO 394 394 394 PRO PRO B . n 
B 1 395 MET 395 395 395 MET MET B . n 
B 1 396 CYS 396 396 396 CYS CYS B . n 
B 1 397 ASP 397 397 397 ASP ASP B . n 
B 1 398 ALA 398 398 398 ALA ALA B . n 
B 1 399 ASN 399 399 399 ASN ASN B . n 
B 1 400 PRO 400 400 400 PRO PRO B . n 
B 1 401 GLN 401 401 401 GLN GLN B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 THR 403 403 403 THR THR B . n 
B 1 404 HIS 404 404 404 HIS HIS B . n 
B 1 405 ALA 405 405 405 ALA ALA B . n 
B 1 406 TYR 406 406 406 TYR TYR B . n 
B 1 407 VAL 407 407 407 VAL VAL B . n 
B 1 408 TRP 408 408 408 TRP TRP B . n 
B 1 409 ILE 409 409 409 ILE ILE B . n 
B 1 410 SER 410 410 410 SER SER B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 ALA 412 412 412 ALA ALA B . n 
B 1 413 TYR 413 413 413 TYR TYR B . n 
B 1 414 LYS 414 414 414 LYS LYS B . n 
B 1 415 LYS 415 415 415 LYS LYS B . n 
B 1 416 THR 416 416 416 THR THR B . n 
B 1 417 GLY 417 417 417 GLY GLY B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 TYR 419 419 419 TYR TYR B . n 
B 1 420 ILE 420 420 420 ILE ILE B . n 
B 1 421 THR 421 421 421 THR THR B . n 
B 1 422 VAL 422 422 422 VAL VAL B . n 
B 1 423 TYR 423 423 423 TYR TYR B . n 
B 1 424 THR 424 424 424 THR THR B . n 
B 1 425 ASN 425 425 425 ASN ASN B . n 
B 1 426 PRO 426 426 426 PRO PRO B . n 
B 1 427 GLY 427 427 427 GLY GLY B . n 
B 1 428 ALA 428 428 428 ALA ALA B . n 
B 1 429 SER 429 429 429 SER SER B . n 
B 1 430 ILE 430 430 430 ILE ILE B . n 
B 1 431 LEU 431 431 431 LEU LEU B . n 
B 1 432 GLU 432 432 432 GLU GLU B . n 
B 1 433 LYS 433 433 ?   ?   ?   B . n 
B 1 434 ALA 434 434 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   THR 2   2   ?   ?   ?   C . n 
C 1 3   VAL 3   3   ?   ?   ?   C . n 
C 1 4   GLU 4   4   ?   ?   ?   C . n 
C 1 5   HIS 5   5   ?   ?   ?   C . n 
C 1 6   ALA 6   6   ?   ?   ?   C . n 
C 1 7   GLN 7   7   ?   ?   ?   C . n 
C 1 8   LEU 8   8   ?   ?   ?   C . n 
C 1 9   THR 9   9   ?   ?   ?   C . n 
C 1 10  SER 10  10  ?   ?   ?   C . n 
C 1 11  ASN 11  11  ?   ?   ?   C . n 
C 1 12  ASP 12  12  ?   ?   ?   C . n 
C 1 13  LEU 13  13  ?   ?   ?   C . n 
C 1 14  LEU 14  14  ?   ?   ?   C . n 
C 1 15  VAL 15  15  ?   ?   ?   C . n 
C 1 16  LYS 16  16  ?   ?   ?   C . n 
C 1 17  SER 17  17  ?   ?   ?   C . n 
C 1 18  ILE 18  18  ?   ?   ?   C . n 
C 1 19  SER 19  19  ?   ?   ?   C . n 
C 1 20  SER 20  20  ?   ?   ?   C . n 
C 1 21  SER 21  21  ?   ?   ?   C . n 
C 1 22  PRO 22  22  ?   ?   ?   C . n 
C 1 23  SER 23  23  23  SER SER C . n 
C 1 24  PRO 24  24  24  PRO PRO C . n 
C 1 25  SER 25  25  25  SER SER C . n 
C 1 26  PRO 26  26  26  PRO PRO C . n 
C 1 27  TRP 27  27  27  TRP TRP C . n 
C 1 28  ASP 28  28  28  ASP ASP C . n 
C 1 29  PHE 29  29  29  PHE PHE C . n 
C 1 30  LEU 30  30  30  LEU LEU C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  ARG 32  32  32  ARG ARG C . n 
C 1 33  VAL 33  33  33  VAL VAL C . n 
C 1 34  LEU 34  34  34  LEU LEU C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  PHE 36  36  36  PHE PHE C . n 
C 1 37  GLN 37  37  37  GLN GLN C . n 
C 1 38  HIS 38  38  38  HIS HIS C . n 
C 1 39  GLY 39  39  39  GLY GLY C . n 
C 1 40  ASP 40  40  40  ASP ASP C . n 
C 1 41  HIS 41  41  41  HIS HIS C . n 
C 1 42  LYS 42  42  42  LYS LYS C . n 
C 1 43  ARG 43  43  43  ARG ARG C . n 
C 1 44  TRP 44  44  44  TRP TRP C . n 
C 1 45  TRP 45  45  45  TRP TRP C . n 
C 1 46  ASP 46  46  46  ASP ASP C . n 
C 1 47  VAL 47  47  47  VAL VAL C . n 
C 1 48  LEU 48  48  48  LEU LEU C . n 
C 1 49  ALA 49  49  49  ALA ALA C . n 
C 1 50  PRO 50  50  50  PRO PRO C . n 
C 1 51  VAL 51  51  51  VAL VAL C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  GLY 53  53  53  GLY GLY C . n 
C 1 54  ILE 54  54  54  ILE ILE C . n 
C 1 55  SER 55  55  55  SER SER C . n 
C 1 56  MET 56  56  56  MET MET C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  SER 58  58  58  SER SER C . n 
C 1 59  ILE 59  59  59  ILE ILE C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  TYR 61  61  61  TYR TYR C . n 
C 1 62  LYS 62  62  62  LYS LYS C . n 
C 1 63  LEU 63  63  63  LEU LEU C . n 
C 1 64  ASP 64  64  64  ASP ASP C . n 
C 1 65  VAL 65  65  65  VAL VAL C . n 
C 1 66  GLN 66  66  66  GLN GLN C . n 
C 1 67  TYR 67  67  67  TYR TYR C . n 
C 1 68  ARG 68  68  68  ARG ARG C . n 
C 1 69  HIS 69  69  69  HIS HIS C . n 
C 1 70  LEU 70  70  70  LEU LEU C . n 
C 1 71  LEU 71  71  71  LEU LEU C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  LEU 73  73  73  LEU LEU C . n 
C 1 74  TYR 74  74  74  TYR TYR C . n 
C 1 75  ASP 75  75  75  ASP ASP C . n 
C 1 76  ALA 76  76  76  ALA ALA C . n 
C 1 77  VAL 77  77  77  VAL VAL C . n 
C 1 78  ILE 78  78  78  ILE ILE C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  ASN 80  80  80  ASN ASN C . n 
C 1 81  MET 81  81  81  MET MET C . n 
C 1 82  GLY 82  82  82  GLY GLY C . n 
C 1 83  PRO 83  83  83  PRO PRO C . n 
C 1 84  PHE 84  84  84  PHE PHE C . n 
C 1 85  PRO 85  85  85  PRO PRO C . n 
C 1 86  ASN 86  86  86  ASN ASN C . n 
C 1 87  SER 87  87  87  SER SER C . n 
C 1 88  ASN 88  88  88  ASN ASN C . n 
C 1 89  ALA 89  89  89  ALA ALA C . n 
C 1 90  SER 90  90  90  SER SER C . n 
C 1 91  ASN 91  91  91  ASN ASN C . n 
C 1 92  ILE 92  92  92  ILE ILE C . n 
C 1 93  THR 93  93  93  THR THR C . n 
C 1 94  TRP 94  94  94  TRP TRP C . n 
C 1 95  THR 95  95  95  THR THR C . n 
C 1 96  SER 96  96  96  SER SER C . n 
C 1 97  PRO 97  97  97  PRO PRO C . n 
C 1 98  PHE 98  98  98  PHE PHE C . n 
C 1 99  PRO 99  99  99  PRO PRO C . n 
C 1 100 PRO 100 100 100 PRO PRO C . n 
C 1 101 GLY 101 101 101 GLY GLY C . n 
C 1 102 PRO 102 102 102 PRO PRO C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 ALA 105 105 105 ALA ALA C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 VAL 107 107 107 VAL VAL C . n 
C 1 108 ASN 108 108 108 ASN ASN C . n 
C 1 109 TYR 109 109 109 TYR TYR C . n 
C 1 110 GLN 110 110 110 GLN GLN C . n 
C 1 111 ALA 111 111 111 ALA ALA C . n 
C 1 112 GLY 112 112 112 GLY GLY C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 SER 114 114 114 SER SER C . n 
C 1 115 SER 115 115 115 SER SER C . n 
C 1 116 MET 116 116 116 MET MET C . n 
C 1 117 PHE 117 117 117 PHE PHE C . n 
C 1 118 ARG 118 118 118 ARG ARG C . n 
C 1 119 PHE 119 119 119 PHE PHE C . n 
C 1 120 THR 120 120 120 THR THR C . n 
C 1 121 ILE 121 121 121 ILE ILE C . n 
C 1 122 GLU 122 122 122 GLU GLU C . n 
C 1 123 PRO 123 123 123 PRO PRO C . n 
C 1 124 VAL 124 124 124 VAL VAL C . n 
C 1 125 GLY 125 125 125 GLY GLY C . n 
C 1 126 PRO 126 126 126 PRO PRO C . n 
C 1 127 HIS 127 127 127 HIS HIS C . n 
C 1 128 ALA 128 128 128 ALA ALA C . n 
C 1 129 GLY 129 129 129 GLY GLY C . n 
C 1 130 THR 130 130 130 THR THR C . n 
C 1 131 PRO 131 131 131 PRO PRO C . n 
C 1 132 ALA 132 132 132 ALA ALA C . n 
C 1 133 ASP 133 133 133 ASP ASP C . n 
C 1 134 PRO 134 134 134 PRO PRO C . n 
C 1 135 VAL 135 135 135 VAL VAL C . n 
C 1 136 ASN 136 136 136 ASN ASN C . n 
C 1 137 GLU 137 137 137 GLU GLU C . n 
C 1 138 LEU 138 138 138 LEU LEU C . n 
C 1 139 ALA 139 139 139 ALA ALA C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 LYS 141 141 141 LYS LYS C . n 
C 1 142 GLN 142 142 142 GLN GLN C . n 
C 1 143 LEU 143 143 143 LEU LEU C . n 
C 1 144 MET 144 144 144 MET MET C . n 
C 1 145 GLN 145 145 145 GLN GLN C . n 
C 1 146 ARG 146 146 146 ARG ARG C . n 
C 1 147 LEU 147 147 147 LEU LEU C . n 
C 1 148 GLY 148 148 148 GLY GLY C . n 
C 1 149 GLN 149 149 149 GLN GLN C . n 
C 1 150 LEU 150 150 150 LEU LEU C . n 
C 1 151 GLN 151 151 151 GLN GLN C . n 
C 1 152 PRO 152 152 152 PRO PRO C . n 
C 1 153 GLY 153 153 153 GLY GLY C . n 
C 1 154 GLY 154 154 154 GLY GLY C . n 
C 1 155 VAL 155 155 155 VAL VAL C . n 
C 1 156 ASP 156 156 156 ASP ASP C . n 
C 1 157 SER 157 157 157 SER SER C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 MET 159 159 159 MET MET C . n 
C 1 160 PHE 160 160 160 PHE PHE C . n 
C 1 161 ASP 161 161 161 ASP ASP C . n 
C 1 162 HIS 162 162 162 HIS HIS C . n 
C 1 163 PHE 163 163 163 PHE PHE C . n 
C 1 164 TYR 164 164 164 TYR TYR C . n 
C 1 165 PRO 165 165 165 PRO PRO C . n 
C 1 166 LEU 166 166 166 LEU LEU C . n 
C 1 167 LEU 167 167 167 LEU LEU C . n 
C 1 168 CYS 168 168 168 CYS CYS C . n 
C 1 169 VAL 169 169 169 VAL VAL C . n 
C 1 170 ASP 170 170 170 ASP ASP C . n 
C 1 171 GLY 171 171 171 GLY GLY C . n 
C 1 172 PRO 172 172 172 PRO PRO C . n 
C 1 173 GLU 173 173 173 GLU GLU C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 ARG 175 175 175 ARG ARG C . n 
C 1 176 ARG 176 176 176 ARG ARG C . n 
C 1 177 GLN 177 177 177 GLN GLN C . n 
C 1 178 TRP 178 178 178 TRP TRP C . n 
C 1 179 ASP 179 179 179 ASP ASP C . n 
C 1 180 SER 180 180 180 SER SER C . n 
C 1 181 ILE 181 181 181 ILE ILE C . n 
C 1 182 ALA 182 182 182 ALA ALA C . n 
C 1 183 HIS 183 183 183 HIS HIS C . n 
C 1 184 ILE 184 184 184 ILE ILE C . n 
C 1 185 TYR 185 185 185 TYR TYR C . n 
C 1 186 HIS 186 186 186 HIS HIS C . n 
C 1 187 LYS 187 187 187 LYS LYS C . n 
C 1 188 CYS 188 188 188 CYS CYS C . n 
C 1 189 HIS 189 189 189 HIS HIS C . n 
C 1 190 THR 190 190 190 THR THR C . n 
C 1 191 VAL 191 191 191 VAL VAL C . n 
C 1 192 THR 192 192 192 THR THR C . n 
C 1 193 ALA 193 193 193 ALA ALA C . n 
C 1 194 LEU 194 194 194 LEU LEU C . n 
C 1 195 ASP 195 195 195 ASP ASP C . n 
C 1 196 MET 196 196 196 MET MET C . n 
C 1 197 GLN 197 197 197 GLN GLN C . n 
C 1 198 ARG 198 198 198 ARG ARG C . n 
C 1 199 SER 199 199 199 SER SER C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 ALA 201 201 201 ALA ALA C . n 
C 1 202 CYS 202 202 202 CYS CYS C . n 
C 1 203 THR 203 203 203 THR THR C . n 
C 1 204 LEU 204 204 204 LEU LEU C . n 
C 1 205 LYS 205 205 205 LYS LYS C . n 
C 1 206 THR 206 206 206 THR THR C . n 
C 1 207 ALA 207 207 207 ALA ALA C . n 
C 1 208 PHE 208 208 208 PHE PHE C . n 
C 1 209 PRO 209 209 209 PRO PRO C . n 
C 1 210 PRO 210 210 210 PRO PRO C . n 
C 1 211 LEU 211 211 211 LEU LEU C . n 
C 1 212 LEU 212 212 212 LEU LEU C . n 
C 1 213 ARG 213 213 213 ARG ARG C . n 
C 1 214 SER 214 214 214 SER SER C . n 
C 1 215 THR 215 215 215 THR THR C . n 
C 1 216 ILE 216 216 216 ILE ILE C . n 
C 1 217 MET 217 217 217 MET MET C . n 
C 1 218 ASN 218 218 218 ASN ASN C . n 
C 1 219 THR 219 219 219 THR THR C . n 
C 1 220 SER 220 220 220 SER SER C . n 
C 1 221 MET 221 221 221 MET MET C . n 
C 1 222 VAL 222 222 222 VAL VAL C . n 
C 1 223 ASP 223 223 223 ASP ASP C . n 
C 1 224 ILE 224 224 224 ILE ILE C . n 
C 1 225 MET 225 225 225 MET MET C . n 
C 1 226 PHE 226 226 226 PHE PHE C . n 
C 1 227 ASP 227 227 227 ASP ASP C . n 
C 1 228 ALA 228 228 228 ALA ALA C . n 
C 1 229 VAL 229 229 229 VAL VAL C . n 
C 1 230 GLU 230 230 230 GLU GLU C . n 
C 1 231 SER 231 231 231 SER SER C . n 
C 1 232 PHE 232 232 232 PHE PHE C . n 
C 1 233 ARG 233 233 233 ARG ARG C . n 
C 1 234 LYS 234 234 234 LYS LYS C . n 
C 1 235 GLN 235 235 235 GLN GLN C . n 
C 1 236 SER 236 236 236 SER SER C . n 
C 1 237 GLY 237 237 237 GLY GLY C . n 
C 1 238 LEU 238 238 238 LEU LEU C . n 
C 1 239 TYR 239 239 239 TYR TYR C . n 
C 1 240 PHE 240 240 240 PHE PHE C . n 
C 1 241 ASP 241 241 241 ASP ASP C . n 
C 1 242 TYR 242 242 242 TYR TYR C . n 
C 1 243 THR 243 243 243 THR THR C . n 
C 1 244 LYS 244 244 244 LYS LYS C . n 
C 1 245 ILE 245 245 245 ILE ILE C . n 
C 1 246 LYS 246 246 246 LYS LYS C . n 
C 1 247 GLU 247 247 247 GLU GLU C . n 
C 1 248 PHE 248 248 248 PHE PHE C . n 
C 1 249 MET 249 249 249 MET MET C . n 
C 1 250 SER 250 250 250 SER SER C . n 
C 1 251 GLU 251 251 251 GLU GLU C . n 
C 1 252 GLU 252 252 252 GLU GLU C . n 
C 1 253 LYS 253 253 253 LYS LYS C . n 
C 1 254 THR 254 254 254 THR THR C . n 
C 1 255 HIS 255 255 255 HIS HIS C . n 
C 1 256 GLU 256 256 256 GLU GLU C . n 
C 1 257 THR 257 257 257 THR THR C . n 
C 1 258 MET 258 258 258 MET MET C . n 
C 1 259 MET 259 259 259 MET MET C . n 
C 1 260 VAL 260 260 260 VAL VAL C . n 
C 1 261 ASP 261 261 261 ASP ASP C . n 
C 1 262 ARG 262 262 262 ARG ARG C . n 
C 1 263 SER 263 263 263 SER SER C . n 
C 1 264 TYR 264 264 264 TYR TYR C . n 
C 1 265 LEU 265 265 265 LEU LEU C . n 
C 1 266 SER 266 266 266 SER SER C . n 
C 1 267 PHE 267 267 267 PHE PHE C . n 
C 1 268 ASP 268 268 268 ASP ASP C . n 
C 1 269 CYS 269 269 269 CYS CYS C . n 
C 1 270 LEU 270 270 270 LEU LEU C . n 
C 1 271 ASP 271 271 271 ASP ASP C . n 
C 1 272 PRO 272 272 272 PRO PRO C . n 
C 1 273 ALA 273 273 273 ALA ALA C . n 
C 1 274 LYS 274 274 274 LYS LYS C . n 
C 1 275 SER 275 275 275 SER SER C . n 
C 1 276 ARG 276 276 276 ARG ARG C . n 
C 1 277 ILE 277 277 277 ILE ILE C . n 
C 1 278 LYS 278 278 278 LYS LYS C . n 
C 1 279 ILE 279 279 279 ILE ILE C . n 
C 1 280 TYR 280 280 280 TYR TYR C . n 
C 1 281 THR 281 281 281 THR THR C . n 
C 1 282 GLU 282 282 282 GLU GLU C . n 
C 1 283 ALA 283 283 283 ALA ALA C . n 
C 1 284 LYS 284 284 284 LYS LYS C . n 
C 1 285 VAL 285 285 285 VAL VAL C . n 
C 1 286 LYS 286 286 286 LYS LYS C . n 
C 1 287 THR 287 287 287 THR THR C . n 
C 1 288 LEU 288 288 288 LEU LEU C . n 
C 1 289 GLU 289 289 289 GLU GLU C . n 
C 1 290 GLU 290 290 290 GLU GLU C . n 
C 1 291 ALA 291 291 291 ALA ALA C . n 
C 1 292 TYR 292 292 292 TYR TYR C . n 
C 1 293 SER 293 293 293 SER SER C . n 
C 1 294 PHE 294 294 294 PHE PHE C . n 
C 1 295 TRP 295 295 295 TRP TRP C . n 
C 1 296 SER 296 296 296 SER SER C . n 
C 1 297 LEU 297 297 297 LEU LEU C . n 
C 1 298 GLY 298 298 298 GLY GLY C . n 
C 1 299 GLY 299 299 299 GLY GLY C . n 
C 1 300 ARG 300 300 300 ARG ARG C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 SER 302 302 302 SER SER C . n 
C 1 303 GLY 303 303 303 GLY GLY C . n 
C 1 304 PRO 304 304 304 PRO PRO C . n 
C 1 305 GLU 305 305 305 GLU GLU C . n 
C 1 306 ILE 306 306 306 ILE ILE C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 TYR 308 308 308 TYR TYR C . n 
C 1 309 GLY 309 309 309 GLY GLY C . n 
C 1 310 PHE 310 310 310 PHE PHE C . n 
C 1 311 LYS 311 311 311 LYS LYS C . n 
C 1 312 ILE 312 312 312 ILE ILE C . n 
C 1 313 VAL 313 313 313 VAL VAL C . n 
C 1 314 SER 314 314 314 SER SER C . n 
C 1 315 GLN 315 315 315 GLN GLN C . n 
C 1 316 MET 316 316 316 MET MET C . n 
C 1 317 TRP 317 317 317 TRP TRP C . n 
C 1 318 ASP 318 318 318 ASP ASP C . n 
C 1 319 ALA 319 319 319 ALA ALA C . n 
C 1 320 ILE 320 320 320 ILE ILE C . n 
C 1 321 TYR 321 321 321 TYR TYR C . n 
C 1 322 SER 322 322 322 SER SER C . n 
C 1 323 LYS 323 323 323 LYS LYS C . n 
C 1 324 GLU 324 324 324 GLU GLU C . n 
C 1 325 LEU 325 325 325 LEU LEU C . n 
C 1 326 PRO 326 326 326 PRO PRO C . n 
C 1 327 GLY 327 327 327 GLY GLY C . n 
C 1 328 GLY 328 328 328 GLY GLY C . n 
C 1 329 LYS 329 329 329 LYS LYS C . n 
C 1 330 GLN 330 330 330 GLN GLN C . n 
C 1 331 ARG 331 331 331 ARG ARG C . n 
C 1 332 GLU 332 332 332 GLU GLU C . n 
C 1 333 ASN 333 333 333 ASN ASN C . n 
C 1 334 ASN 334 334 334 ASN ASN C . n 
C 1 335 HIS 335 335 335 HIS HIS C . n 
C 1 336 ILE 336 336 336 ILE ILE C . n 
C 1 337 GLN 337 337 337 GLN GLN C . n 
C 1 338 ILE 338 338 338 ILE ILE C . n 
C 1 339 ASN 339 339 339 ASN ASN C . n 
C 1 340 TRP 340 340 340 TRP TRP C . n 
C 1 341 GLU 341 341 341 GLU GLU C . n 
C 1 342 MET 342 342 342 MET MET C . n 
C 1 343 SER 343 343 343 SER SER C . n 
C 1 344 ALA 344 344 344 ALA ALA C . n 
C 1 345 LYS 345 345 345 LYS LYS C . n 
C 1 346 ASP 346 346 346 ASP ASP C . n 
C 1 347 SER 347 347 347 SER SER C . n 
C 1 348 SER 348 348 348 SER SER C . n 
C 1 349 VAL 349 349 349 VAL VAL C . n 
C 1 350 ALA 350 350 350 ALA ALA C . n 
C 1 351 PRO 351 351 351 PRO PRO C . n 
C 1 352 LYS 352 352 352 LYS LYS C . n 
C 1 353 LEU 353 353 353 LEU LEU C . n 
C 1 354 TYR 354 354 354 TYR TYR C . n 
C 1 355 LEU 355 355 355 LEU LEU C . n 
C 1 356 THR 356 356 356 THR THR C . n 
C 1 357 VAL 357 357 357 VAL VAL C . n 
C 1 358 ILE 358 358 358 ILE ILE C . n 
C 1 359 GLU 359 359 359 GLU GLU C . n 
C 1 360 ASP 360 360 360 ASP ASP C . n 
C 1 361 TYR 361 361 361 TYR TYR C . n 
C 1 362 ASP 362 362 362 ASP ASP C . n 
C 1 363 ALA 363 363 363 ALA ALA C . n 
C 1 364 TYR 364 364 364 TYR TYR C . n 
C 1 365 VAL 365 365 365 VAL VAL C . n 
C 1 366 SER 366 366 366 SER SER C . n 
C 1 367 SER 367 367 367 SER SER C . n 
C 1 368 ALA 368 368 368 ALA ALA C . n 
C 1 369 ILE 369 369 369 ILE ILE C . n 
C 1 370 VAL 370 370 370 VAL VAL C . n 
C 1 371 ASP 371 371 371 ASP ASP C . n 
C 1 372 LEU 372 372 372 LEU LEU C . n 
C 1 373 PHE 373 373 373 PHE PHE C . n 
C 1 374 THR 374 374 374 THR THR C . n 
C 1 375 GLY 375 375 375 GLY GLY C . n 
C 1 376 LEU 376 376 376 LEU LEU C . n 
C 1 377 GLY 377 377 377 GLY GLY C . n 
C 1 378 TRP 378 378 378 TRP TRP C . n 
C 1 379 ALA 379 379 379 ALA ALA C . n 
C 1 380 ALA 380 380 380 ALA ALA C . n 
C 1 381 HIS 381 381 381 HIS HIS C . n 
C 1 382 VAL 382 382 382 VAL VAL C . n 
C 1 383 GLN 383 383 383 GLN GLN C . n 
C 1 384 THR 384 384 384 THR THR C . n 
C 1 385 HIS 385 385 385 HIS HIS C . n 
C 1 386 LYS 386 386 386 LYS LYS C . n 
C 1 387 LYS 387 387 387 LYS LYS C . n 
C 1 388 ILE 388 388 388 ILE ILE C . n 
C 1 389 GLU 389 389 389 GLU GLU C . n 
C 1 390 LYS 390 390 390 LYS LYS C . n 
C 1 391 GLU 391 391 391 GLU GLU C . n 
C 1 392 ALA 392 392 392 ALA ALA C . n 
C 1 393 TYR 393 393 393 TYR TYR C . n 
C 1 394 PRO 394 394 394 PRO PRO C . n 
C 1 395 MET 395 395 395 MET MET C . n 
C 1 396 CYS 396 396 396 CYS CYS C . n 
C 1 397 ASP 397 397 397 ASP ASP C . n 
C 1 398 ALA 398 398 398 ALA ALA C . n 
C 1 399 ASN 399 399 399 ASN ASN C . n 
C 1 400 PRO 400 400 400 PRO PRO C . n 
C 1 401 GLN 401 401 401 GLN GLN C . n 
C 1 402 SER 402 402 402 SER SER C . n 
C 1 403 THR 403 403 403 THR THR C . n 
C 1 404 HIS 404 404 404 HIS HIS C . n 
C 1 405 ALA 405 405 405 ALA ALA C . n 
C 1 406 TYR 406 406 406 TYR TYR C . n 
C 1 407 VAL 407 407 407 VAL VAL C . n 
C 1 408 TRP 408 408 408 TRP TRP C . n 
C 1 409 ILE 409 409 409 ILE ILE C . n 
C 1 410 SER 410 410 410 SER SER C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 ALA 412 412 412 ALA ALA C . n 
C 1 413 TYR 413 413 413 TYR TYR C . n 
C 1 414 LYS 414 414 414 LYS LYS C . n 
C 1 415 LYS 415 415 415 LYS LYS C . n 
C 1 416 THR 416 416 416 THR THR C . n 
C 1 417 GLY 417 417 417 GLY GLY C . n 
C 1 418 PRO 418 418 418 PRO PRO C . n 
C 1 419 TYR 419 419 419 TYR TYR C . n 
C 1 420 ILE 420 420 420 ILE ILE C . n 
C 1 421 THR 421 421 421 THR THR C . n 
C 1 422 VAL 422 422 422 VAL VAL C . n 
C 1 423 TYR 423 423 423 TYR TYR C . n 
C 1 424 THR 424 424 424 THR THR C . n 
C 1 425 ASN 425 425 425 ASN ASN C . n 
C 1 426 PRO 426 426 426 PRO PRO C . n 
C 1 427 GLY 427 427 427 GLY GLY C . n 
C 1 428 ALA 428 428 428 ALA ALA C . n 
C 1 429 SER 429 429 429 SER SER C . n 
C 1 430 ILE 430 430 430 ILE ILE C . n 
C 1 431 LEU 431 431 431 LEU LEU C . n 
C 1 432 GLU 432 432 432 GLU GLU C . n 
C 1 433 LYS 433 433 ?   ?   ?   C . n 
C 1 434 ALA 434 434 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   THR 2   2   ?   ?   ?   D . n 
D 1 3   VAL 3   3   ?   ?   ?   D . n 
D 1 4   GLU 4   4   ?   ?   ?   D . n 
D 1 5   HIS 5   5   ?   ?   ?   D . n 
D 1 6   ALA 6   6   ?   ?   ?   D . n 
D 1 7   GLN 7   7   ?   ?   ?   D . n 
D 1 8   LEU 8   8   ?   ?   ?   D . n 
D 1 9   THR 9   9   ?   ?   ?   D . n 
D 1 10  SER 10  10  ?   ?   ?   D . n 
D 1 11  ASN 11  11  ?   ?   ?   D . n 
D 1 12  ASP 12  12  ?   ?   ?   D . n 
D 1 13  LEU 13  13  ?   ?   ?   D . n 
D 1 14  LEU 14  14  ?   ?   ?   D . n 
D 1 15  VAL 15  15  ?   ?   ?   D . n 
D 1 16  LYS 16  16  ?   ?   ?   D . n 
D 1 17  SER 17  17  ?   ?   ?   D . n 
D 1 18  ILE 18  18  ?   ?   ?   D . n 
D 1 19  SER 19  19  ?   ?   ?   D . n 
D 1 20  SER 20  20  ?   ?   ?   D . n 
D 1 21  SER 21  21  ?   ?   ?   D . n 
D 1 22  PRO 22  22  ?   ?   ?   D . n 
D 1 23  SER 23  23  23  SER SER D . n 
D 1 24  PRO 24  24  24  PRO PRO D . n 
D 1 25  SER 25  25  25  SER SER D . n 
D 1 26  PRO 26  26  26  PRO PRO D . n 
D 1 27  TRP 27  27  27  TRP TRP D . n 
D 1 28  ASP 28  28  28  ASP ASP D . n 
D 1 29  PHE 29  29  29  PHE PHE D . n 
D 1 30  LEU 30  30  30  LEU LEU D . n 
D 1 31  GLY 31  31  31  GLY GLY D . n 
D 1 32  ARG 32  32  32  ARG ARG D . n 
D 1 33  VAL 33  33  33  VAL VAL D . n 
D 1 34  LEU 34  34  34  LEU LEU D . n 
D 1 35  GLN 35  35  35  GLN GLN D . n 
D 1 36  PHE 36  36  36  PHE PHE D . n 
D 1 37  GLN 37  37  37  GLN GLN D . n 
D 1 38  HIS 38  38  38  HIS HIS D . n 
D 1 39  GLY 39  39  39  GLY GLY D . n 
D 1 40  ASP 40  40  40  ASP ASP D . n 
D 1 41  HIS 41  41  41  HIS HIS D . n 
D 1 42  LYS 42  42  42  LYS LYS D . n 
D 1 43  ARG 43  43  43  ARG ARG D . n 
D 1 44  TRP 44  44  44  TRP TRP D . n 
D 1 45  TRP 45  45  45  TRP TRP D . n 
D 1 46  ASP 46  46  46  ASP ASP D . n 
D 1 47  VAL 47  47  47  VAL VAL D . n 
D 1 48  LEU 48  48  48  LEU LEU D . n 
D 1 49  ALA 49  49  49  ALA ALA D . n 
D 1 50  PRO 50  50  50  PRO PRO D . n 
D 1 51  VAL 51  51  51  VAL VAL D . n 
D 1 52  PHE 52  52  52  PHE PHE D . n 
D 1 53  GLY 53  53  53  GLY GLY D . n 
D 1 54  ILE 54  54  54  ILE ILE D . n 
D 1 55  SER 55  55  55  SER SER D . n 
D 1 56  MET 56  56  56  MET MET D . n 
D 1 57  ALA 57  57  57  ALA ALA D . n 
D 1 58  SER 58  58  58  SER SER D . n 
D 1 59  ILE 59  59  59  ILE ILE D . n 
D 1 60  GLY 60  60  60  GLY GLY D . n 
D 1 61  TYR 61  61  61  TYR TYR D . n 
D 1 62  LYS 62  62  62  LYS LYS D . n 
D 1 63  LEU 63  63  63  LEU LEU D . n 
D 1 64  ASP 64  64  64  ASP ASP D . n 
D 1 65  VAL 65  65  65  VAL VAL D . n 
D 1 66  GLN 66  66  66  GLN GLN D . n 
D 1 67  TYR 67  67  67  TYR TYR D . n 
D 1 68  ARG 68  68  68  ARG ARG D . n 
D 1 69  HIS 69  69  69  HIS HIS D . n 
D 1 70  LEU 70  70  70  LEU LEU D . n 
D 1 71  LEU 71  71  71  LEU LEU D . n 
D 1 72  VAL 72  72  72  VAL VAL D . n 
D 1 73  LEU 73  73  73  LEU LEU D . n 
D 1 74  TYR 74  74  74  TYR TYR D . n 
D 1 75  ASP 75  75  75  ASP ASP D . n 
D 1 76  ALA 76  76  76  ALA ALA D . n 
D 1 77  VAL 77  77  77  VAL VAL D . n 
D 1 78  ILE 78  78  78  ILE ILE D . n 
D 1 79  PRO 79  79  79  PRO PRO D . n 
D 1 80  ASN 80  80  80  ASN ASN D . n 
D 1 81  MET 81  81  81  MET MET D . n 
D 1 82  GLY 82  82  82  GLY GLY D . n 
D 1 83  PRO 83  83  83  PRO PRO D . n 
D 1 84  PHE 84  84  84  PHE PHE D . n 
D 1 85  PRO 85  85  85  PRO PRO D . n 
D 1 86  ASN 86  86  86  ASN ASN D . n 
D 1 87  SER 87  87  87  SER SER D . n 
D 1 88  ASN 88  88  88  ASN ASN D . n 
D 1 89  ALA 89  89  89  ALA ALA D . n 
D 1 90  SER 90  90  90  SER SER D . n 
D 1 91  ASN 91  91  91  ASN ASN D . n 
D 1 92  ILE 92  92  92  ILE ILE D . n 
D 1 93  THR 93  93  93  THR THR D . n 
D 1 94  TRP 94  94  94  TRP TRP D . n 
D 1 95  THR 95  95  95  THR THR D . n 
D 1 96  SER 96  96  96  SER SER D . n 
D 1 97  PRO 97  97  97  PRO PRO D . n 
D 1 98  PHE 98  98  98  PHE PHE D . n 
D 1 99  PRO 99  99  99  PRO PRO D . n 
D 1 100 PRO 100 100 100 PRO PRO D . n 
D 1 101 GLY 101 101 101 GLY GLY D . n 
D 1 102 PRO 102 102 102 PRO PRO D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 GLU 104 104 104 GLU GLU D . n 
D 1 105 ALA 105 105 105 ALA ALA D . n 
D 1 106 SER 106 106 106 SER SER D . n 
D 1 107 VAL 107 107 107 VAL VAL D . n 
D 1 108 ASN 108 108 108 ASN ASN D . n 
D 1 109 TYR 109 109 109 TYR TYR D . n 
D 1 110 GLN 110 110 110 GLN GLN D . n 
D 1 111 ALA 111 111 111 ALA ALA D . n 
D 1 112 GLY 112 112 112 GLY GLY D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 SER 114 114 114 SER SER D . n 
D 1 115 SER 115 115 115 SER SER D . n 
D 1 116 MET 116 116 116 MET MET D . n 
D 1 117 PHE 117 117 117 PHE PHE D . n 
D 1 118 ARG 118 118 118 ARG ARG D . n 
D 1 119 PHE 119 119 119 PHE PHE D . n 
D 1 120 THR 120 120 120 THR THR D . n 
D 1 121 ILE 121 121 121 ILE ILE D . n 
D 1 122 GLU 122 122 122 GLU GLU D . n 
D 1 123 PRO 123 123 123 PRO PRO D . n 
D 1 124 VAL 124 124 124 VAL VAL D . n 
D 1 125 GLY 125 125 125 GLY GLY D . n 
D 1 126 PRO 126 126 126 PRO PRO D . n 
D 1 127 HIS 127 127 127 HIS HIS D . n 
D 1 128 ALA 128 128 128 ALA ALA D . n 
D 1 129 GLY 129 129 129 GLY GLY D . n 
D 1 130 THR 130 130 130 THR THR D . n 
D 1 131 PRO 131 131 131 PRO PRO D . n 
D 1 132 ALA 132 132 132 ALA ALA D . n 
D 1 133 ASP 133 133 133 ASP ASP D . n 
D 1 134 PRO 134 134 134 PRO PRO D . n 
D 1 135 VAL 135 135 135 VAL VAL D . n 
D 1 136 ASN 136 136 136 ASN ASN D . n 
D 1 137 GLU 137 137 137 GLU GLU D . n 
D 1 138 LEU 138 138 138 LEU LEU D . n 
D 1 139 ALA 139 139 139 ALA ALA D . n 
D 1 140 ALA 140 140 140 ALA ALA D . n 
D 1 141 LYS 141 141 141 LYS LYS D . n 
D 1 142 GLN 142 142 142 GLN GLN D . n 
D 1 143 LEU 143 143 143 LEU LEU D . n 
D 1 144 MET 144 144 144 MET MET D . n 
D 1 145 GLN 145 145 145 GLN GLN D . n 
D 1 146 ARG 146 146 146 ARG ARG D . n 
D 1 147 LEU 147 147 147 LEU LEU D . n 
D 1 148 GLY 148 148 148 GLY GLY D . n 
D 1 149 GLN 149 149 149 GLN GLN D . n 
D 1 150 LEU 150 150 150 LEU LEU D . n 
D 1 151 GLN 151 151 151 GLN GLN D . n 
D 1 152 PRO 152 152 152 PRO PRO D . n 
D 1 153 GLY 153 153 153 GLY GLY D . n 
D 1 154 GLY 154 154 154 GLY GLY D . n 
D 1 155 VAL 155 155 155 VAL VAL D . n 
D 1 156 ASP 156 156 156 ASP ASP D . n 
D 1 157 SER 157 157 157 SER SER D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 MET 159 159 159 MET MET D . n 
D 1 160 PHE 160 160 160 PHE PHE D . n 
D 1 161 ASP 161 161 161 ASP ASP D . n 
D 1 162 HIS 162 162 162 HIS HIS D . n 
D 1 163 PHE 163 163 163 PHE PHE D . n 
D 1 164 TYR 164 164 164 TYR TYR D . n 
D 1 165 PRO 165 165 165 PRO PRO D . n 
D 1 166 LEU 166 166 166 LEU LEU D . n 
D 1 167 LEU 167 167 167 LEU LEU D . n 
D 1 168 CYS 168 168 168 CYS CYS D . n 
D 1 169 VAL 169 169 169 VAL VAL D . n 
D 1 170 ASP 170 170 170 ASP ASP D . n 
D 1 171 GLY 171 171 171 GLY GLY D . n 
D 1 172 PRO 172 172 172 PRO PRO D . n 
D 1 173 GLU 173 173 173 GLU GLU D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 ARG 175 175 175 ARG ARG D . n 
D 1 176 ARG 176 176 176 ARG ARG D . n 
D 1 177 GLN 177 177 177 GLN GLN D . n 
D 1 178 TRP 178 178 178 TRP TRP D . n 
D 1 179 ASP 179 179 179 ASP ASP D . n 
D 1 180 SER 180 180 180 SER SER D . n 
D 1 181 ILE 181 181 181 ILE ILE D . n 
D 1 182 ALA 182 182 182 ALA ALA D . n 
D 1 183 HIS 183 183 183 HIS HIS D . n 
D 1 184 ILE 184 184 184 ILE ILE D . n 
D 1 185 TYR 185 185 185 TYR TYR D . n 
D 1 186 HIS 186 186 186 HIS HIS D . n 
D 1 187 LYS 187 187 187 LYS LYS D . n 
D 1 188 CYS 188 188 188 CYS CYS D . n 
D 1 189 HIS 189 189 189 HIS HIS D . n 
D 1 190 THR 190 190 190 THR THR D . n 
D 1 191 VAL 191 191 191 VAL VAL D . n 
D 1 192 THR 192 192 192 THR THR D . n 
D 1 193 ALA 193 193 193 ALA ALA D . n 
D 1 194 LEU 194 194 194 LEU LEU D . n 
D 1 195 ASP 195 195 195 ASP ASP D . n 
D 1 196 MET 196 196 196 MET MET D . n 
D 1 197 GLN 197 197 197 GLN GLN D . n 
D 1 198 ARG 198 198 198 ARG ARG D . n 
D 1 199 SER 199 199 199 SER SER D . n 
D 1 200 ALA 200 200 200 ALA ALA D . n 
D 1 201 ALA 201 201 201 ALA ALA D . n 
D 1 202 CYS 202 202 202 CYS CYS D . n 
D 1 203 THR 203 203 203 THR THR D . n 
D 1 204 LEU 204 204 204 LEU LEU D . n 
D 1 205 LYS 205 205 205 LYS LYS D . n 
D 1 206 THR 206 206 206 THR THR D . n 
D 1 207 ALA 207 207 207 ALA ALA D . n 
D 1 208 PHE 208 208 208 PHE PHE D . n 
D 1 209 PRO 209 209 209 PRO PRO D . n 
D 1 210 PRO 210 210 210 PRO PRO D . n 
D 1 211 LEU 211 211 211 LEU LEU D . n 
D 1 212 LEU 212 212 212 LEU LEU D . n 
D 1 213 ARG 213 213 213 ARG ARG D . n 
D 1 214 SER 214 214 214 SER SER D . n 
D 1 215 THR 215 215 215 THR THR D . n 
D 1 216 ILE 216 216 216 ILE ILE D . n 
D 1 217 MET 217 217 217 MET MET D . n 
D 1 218 ASN 218 218 218 ASN ASN D . n 
D 1 219 THR 219 219 219 THR THR D . n 
D 1 220 SER 220 220 220 SER SER D . n 
D 1 221 MET 221 221 221 MET MET D . n 
D 1 222 VAL 222 222 222 VAL VAL D . n 
D 1 223 ASP 223 223 223 ASP ASP D . n 
D 1 224 ILE 224 224 224 ILE ILE D . n 
D 1 225 MET 225 225 225 MET MET D . n 
D 1 226 PHE 226 226 226 PHE PHE D . n 
D 1 227 ASP 227 227 227 ASP ASP D . n 
D 1 228 ALA 228 228 228 ALA ALA D . n 
D 1 229 VAL 229 229 229 VAL VAL D . n 
D 1 230 GLU 230 230 230 GLU GLU D . n 
D 1 231 SER 231 231 231 SER SER D . n 
D 1 232 PHE 232 232 232 PHE PHE D . n 
D 1 233 ARG 233 233 233 ARG ARG D . n 
D 1 234 LYS 234 234 234 LYS LYS D . n 
D 1 235 GLN 235 235 235 GLN GLN D . n 
D 1 236 SER 236 236 236 SER SER D . n 
D 1 237 GLY 237 237 237 GLY GLY D . n 
D 1 238 LEU 238 238 238 LEU LEU D . n 
D 1 239 TYR 239 239 239 TYR TYR D . n 
D 1 240 PHE 240 240 240 PHE PHE D . n 
D 1 241 ASP 241 241 241 ASP ASP D . n 
D 1 242 TYR 242 242 242 TYR TYR D . n 
D 1 243 THR 243 243 243 THR THR D . n 
D 1 244 LYS 244 244 244 LYS LYS D . n 
D 1 245 ILE 245 245 245 ILE ILE D . n 
D 1 246 LYS 246 246 246 LYS LYS D . n 
D 1 247 GLU 247 247 247 GLU GLU D . n 
D 1 248 PHE 248 248 248 PHE PHE D . n 
D 1 249 MET 249 249 249 MET MET D . n 
D 1 250 SER 250 250 250 SER SER D . n 
D 1 251 GLU 251 251 251 GLU GLU D . n 
D 1 252 GLU 252 252 252 GLU GLU D . n 
D 1 253 LYS 253 253 253 LYS LYS D . n 
D 1 254 THR 254 254 254 THR THR D . n 
D 1 255 HIS 255 255 255 HIS HIS D . n 
D 1 256 GLU 256 256 256 GLU GLU D . n 
D 1 257 THR 257 257 257 THR THR D . n 
D 1 258 MET 258 258 258 MET MET D . n 
D 1 259 MET 259 259 259 MET MET D . n 
D 1 260 VAL 260 260 260 VAL VAL D . n 
D 1 261 ASP 261 261 261 ASP ASP D . n 
D 1 262 ARG 262 262 262 ARG ARG D . n 
D 1 263 SER 263 263 263 SER SER D . n 
D 1 264 TYR 264 264 264 TYR TYR D . n 
D 1 265 LEU 265 265 265 LEU LEU D . n 
D 1 266 SER 266 266 266 SER SER D . n 
D 1 267 PHE 267 267 267 PHE PHE D . n 
D 1 268 ASP 268 268 268 ASP ASP D . n 
D 1 269 CYS 269 269 269 CYS CYS D . n 
D 1 270 LEU 270 270 270 LEU LEU D . n 
D 1 271 ASP 271 271 271 ASP ASP D . n 
D 1 272 PRO 272 272 272 PRO PRO D . n 
D 1 273 ALA 273 273 273 ALA ALA D . n 
D 1 274 LYS 274 274 274 LYS LYS D . n 
D 1 275 SER 275 275 275 SER SER D . n 
D 1 276 ARG 276 276 276 ARG ARG D . n 
D 1 277 ILE 277 277 277 ILE ILE D . n 
D 1 278 LYS 278 278 278 LYS LYS D . n 
D 1 279 ILE 279 279 279 ILE ILE D . n 
D 1 280 TYR 280 280 280 TYR TYR D . n 
D 1 281 THR 281 281 281 THR THR D . n 
D 1 282 GLU 282 282 282 GLU GLU D . n 
D 1 283 ALA 283 283 283 ALA ALA D . n 
D 1 284 LYS 284 284 284 LYS LYS D . n 
D 1 285 VAL 285 285 285 VAL VAL D . n 
D 1 286 LYS 286 286 286 LYS LYS D . n 
D 1 287 THR 287 287 287 THR THR D . n 
D 1 288 LEU 288 288 288 LEU LEU D . n 
D 1 289 GLU 289 289 289 GLU GLU D . n 
D 1 290 GLU 290 290 290 GLU GLU D . n 
D 1 291 ALA 291 291 291 ALA ALA D . n 
D 1 292 TYR 292 292 292 TYR TYR D . n 
D 1 293 SER 293 293 293 SER SER D . n 
D 1 294 PHE 294 294 294 PHE PHE D . n 
D 1 295 TRP 295 295 295 TRP TRP D . n 
D 1 296 SER 296 296 296 SER SER D . n 
D 1 297 LEU 297 297 297 LEU LEU D . n 
D 1 298 GLY 298 298 298 GLY GLY D . n 
D 1 299 GLY 299 299 299 GLY GLY D . n 
D 1 300 ARG 300 300 300 ARG ARG D . n 
D 1 301 LEU 301 301 301 LEU LEU D . n 
D 1 302 SER 302 302 302 SER SER D . n 
D 1 303 GLY 303 303 303 GLY GLY D . n 
D 1 304 PRO 304 304 304 PRO PRO D . n 
D 1 305 GLU 305 305 305 GLU GLU D . n 
D 1 306 ILE 306 306 306 ILE ILE D . n 
D 1 307 ASP 307 307 307 ASP ASP D . n 
D 1 308 TYR 308 308 308 TYR TYR D . n 
D 1 309 GLY 309 309 309 GLY GLY D . n 
D 1 310 PHE 310 310 310 PHE PHE D . n 
D 1 311 LYS 311 311 311 LYS LYS D . n 
D 1 312 ILE 312 312 312 ILE ILE D . n 
D 1 313 VAL 313 313 313 VAL VAL D . n 
D 1 314 SER 314 314 314 SER SER D . n 
D 1 315 GLN 315 315 315 GLN GLN D . n 
D 1 316 MET 316 316 316 MET MET D . n 
D 1 317 TRP 317 317 317 TRP TRP D . n 
D 1 318 ASP 318 318 318 ASP ASP D . n 
D 1 319 ALA 319 319 319 ALA ALA D . n 
D 1 320 ILE 320 320 320 ILE ILE D . n 
D 1 321 TYR 321 321 321 TYR TYR D . n 
D 1 322 SER 322 322 322 SER SER D . n 
D 1 323 LYS 323 323 323 LYS LYS D . n 
D 1 324 GLU 324 324 324 GLU GLU D . n 
D 1 325 LEU 325 325 325 LEU LEU D . n 
D 1 326 PRO 326 326 326 PRO PRO D . n 
D 1 327 GLY 327 327 327 GLY GLY D . n 
D 1 328 GLY 328 328 328 GLY GLY D . n 
D 1 329 LYS 329 329 329 LYS LYS D . n 
D 1 330 GLN 330 330 330 GLN GLN D . n 
D 1 331 ARG 331 331 331 ARG ARG D . n 
D 1 332 GLU 332 332 332 GLU GLU D . n 
D 1 333 ASN 333 333 333 ASN ASN D . n 
D 1 334 ASN 334 334 334 ASN ASN D . n 
D 1 335 HIS 335 335 335 HIS HIS D . n 
D 1 336 ILE 336 336 336 ILE ILE D . n 
D 1 337 GLN 337 337 337 GLN GLN D . n 
D 1 338 ILE 338 338 338 ILE ILE D . n 
D 1 339 ASN 339 339 339 ASN ASN D . n 
D 1 340 TRP 340 340 340 TRP TRP D . n 
D 1 341 GLU 341 341 341 GLU GLU D . n 
D 1 342 MET 342 342 342 MET MET D . n 
D 1 343 SER 343 343 343 SER SER D . n 
D 1 344 ALA 344 344 344 ALA ALA D . n 
D 1 345 LYS 345 345 345 LYS LYS D . n 
D 1 346 ASP 346 346 346 ASP ASP D . n 
D 1 347 SER 347 347 347 SER SER D . n 
D 1 348 SER 348 348 348 SER SER D . n 
D 1 349 VAL 349 349 349 VAL VAL D . n 
D 1 350 ALA 350 350 350 ALA ALA D . n 
D 1 351 PRO 351 351 351 PRO PRO D . n 
D 1 352 LYS 352 352 352 LYS LYS D . n 
D 1 353 LEU 353 353 353 LEU LEU D . n 
D 1 354 TYR 354 354 354 TYR TYR D . n 
D 1 355 LEU 355 355 355 LEU LEU D . n 
D 1 356 THR 356 356 356 THR THR D . n 
D 1 357 VAL 357 357 357 VAL VAL D . n 
D 1 358 ILE 358 358 358 ILE ILE D . n 
D 1 359 GLU 359 359 359 GLU GLU D . n 
D 1 360 ASP 360 360 360 ASP ASP D . n 
D 1 361 TYR 361 361 361 TYR TYR D . n 
D 1 362 ASP 362 362 362 ASP ASP D . n 
D 1 363 ALA 363 363 363 ALA ALA D . n 
D 1 364 TYR 364 364 364 TYR TYR D . n 
D 1 365 VAL 365 365 365 VAL VAL D . n 
D 1 366 SER 366 366 366 SER SER D . n 
D 1 367 SER 367 367 367 SER SER D . n 
D 1 368 ALA 368 368 368 ALA ALA D . n 
D 1 369 ILE 369 369 369 ILE ILE D . n 
D 1 370 VAL 370 370 370 VAL VAL D . n 
D 1 371 ASP 371 371 371 ASP ASP D . n 
D 1 372 LEU 372 372 372 LEU LEU D . n 
D 1 373 PHE 373 373 373 PHE PHE D . n 
D 1 374 THR 374 374 374 THR THR D . n 
D 1 375 GLY 375 375 375 GLY GLY D . n 
D 1 376 LEU 376 376 376 LEU LEU D . n 
D 1 377 GLY 377 377 377 GLY GLY D . n 
D 1 378 TRP 378 378 378 TRP TRP D . n 
D 1 379 ALA 379 379 379 ALA ALA D . n 
D 1 380 ALA 380 380 380 ALA ALA D . n 
D 1 381 HIS 381 381 381 HIS HIS D . n 
D 1 382 VAL 382 382 382 VAL VAL D . n 
D 1 383 GLN 383 383 383 GLN GLN D . n 
D 1 384 THR 384 384 384 THR THR D . n 
D 1 385 HIS 385 385 385 HIS HIS D . n 
D 1 386 LYS 386 386 386 LYS LYS D . n 
D 1 387 LYS 387 387 387 LYS LYS D . n 
D 1 388 ILE 388 388 388 ILE ILE D . n 
D 1 389 GLU 389 389 389 GLU GLU D . n 
D 1 390 LYS 390 390 390 LYS LYS D . n 
D 1 391 GLU 391 391 391 GLU GLU D . n 
D 1 392 ALA 392 392 392 ALA ALA D . n 
D 1 393 TYR 393 393 393 TYR TYR D . n 
D 1 394 PRO 394 394 394 PRO PRO D . n 
D 1 395 MET 395 395 395 MET MET D . n 
D 1 396 CYS 396 396 396 CYS CYS D . n 
D 1 397 ASP 397 397 397 ASP ASP D . n 
D 1 398 ALA 398 398 398 ALA ALA D . n 
D 1 399 ASN 399 399 399 ASN ASN D . n 
D 1 400 PRO 400 400 400 PRO PRO D . n 
D 1 401 GLN 401 401 401 GLN GLN D . n 
D 1 402 SER 402 402 402 SER SER D . n 
D 1 403 THR 403 403 403 THR THR D . n 
D 1 404 HIS 404 404 404 HIS HIS D . n 
D 1 405 ALA 405 405 405 ALA ALA D . n 
D 1 406 TYR 406 406 406 TYR TYR D . n 
D 1 407 VAL 407 407 407 VAL VAL D . n 
D 1 408 TRP 408 408 408 TRP TRP D . n 
D 1 409 ILE 409 409 409 ILE ILE D . n 
D 1 410 SER 410 410 410 SER SER D . n 
D 1 411 LEU 411 411 411 LEU LEU D . n 
D 1 412 ALA 412 412 412 ALA ALA D . n 
D 1 413 TYR 413 413 413 TYR TYR D . n 
D 1 414 LYS 414 414 414 LYS LYS D . n 
D 1 415 LYS 415 415 415 LYS LYS D . n 
D 1 416 THR 416 416 416 THR THR D . n 
D 1 417 GLY 417 417 417 GLY GLY D . n 
D 1 418 PRO 418 418 418 PRO PRO D . n 
D 1 419 TYR 419 419 419 TYR TYR D . n 
D 1 420 ILE 420 420 420 ILE ILE D . n 
D 1 421 THR 421 421 421 THR THR D . n 
D 1 422 VAL 422 422 422 VAL VAL D . n 
D 1 423 TYR 423 423 423 TYR TYR D . n 
D 1 424 THR 424 424 424 THR THR D . n 
D 1 425 ASN 425 425 425 ASN ASN D . n 
D 1 426 PRO 426 426 426 PRO PRO D . n 
D 1 427 GLY 427 427 427 GLY GLY D . n 
D 1 428 ALA 428 428 428 ALA ALA D . n 
D 1 429 SER 429 429 429 SER SER D . n 
D 1 430 ILE 430 430 430 ILE ILE D . n 
D 1 431 LEU 431 431 431 LEU LEU D . n 
D 1 432 GLU 432 432 432 GLU GLU D . n 
D 1 433 LYS 433 433 ?   ?   ?   D . n 
D 1 434 ALA 434 434 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        DST 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   DST 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 DST 1 501 501 DST DST A . 
F 2 DST 1 501 501 DST DST B . 
G 2 DST 1 501 501 DST DST C . 
H 2 DST 1 501 501 DST DST D . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JHX 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JHX 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JHX 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9JHX 
_struct.title                        'Versatile Aromatic Prenyltransferase auraA mutant-Y207A in complex with DMSPP' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JHX 
_struct_keywords.text            'Prenyltransferase, Imidazole-Containing Diketopiperazines, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9JHX 
_struct_ref.pdbx_db_accession          9JHX 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JHX A 1 ? 434 ? 9JHX 1 ? 434 ? 1 434 
2 1 9JHX B 1 ? 434 ? 9JHX 1 ? 434 ? 1 434 
3 1 9JHX C 1 ? 434 ? 9JHX 1 ? 434 ? 1 434 
4 1 9JHX D 1 ? 434 ? 9JHX 1 ? 434 ? 1 434 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 25  ? LEU A 34  ? SER A 25  LEU A 34  1 ? 10 
HELX_P HELX_P2  AA2 HIS A 38  ? SER A 58  ? HIS A 38  SER A 58  1 ? 21 
HELX_P HELX_P3  AA3 LYS A 62  ? ALA A 76  ? LYS A 62  ALA A 76  1 ? 15 
HELX_P HELX_P4  AA4 VAL A 77  ? MET A 81  ? VAL A 77  MET A 81  5 ? 5  
HELX_P HELX_P5  AA5 GLU A 137 ? GLN A 151 ? GLU A 137 GLN A 151 1 ? 15 
HELX_P HELX_P6  AA6 SER A 157 ? LEU A 167 ? SER A 157 LEU A 167 1 ? 11 
HELX_P HELX_P7  AA7 ASP A 170 ? GLN A 177 ? ASP A 170 GLN A 177 1 ? 8  
HELX_P HELX_P8  AA8 GLN A 177 ? ALA A 182 ? GLN A 177 ALA A 182 1 ? 6  
HELX_P HELX_P9  AA9 PRO A 210 ? MET A 217 ? PRO A 210 MET A 217 1 ? 8  
HELX_P HELX_P10 AB1 SER A 220 ? GLY A 237 ? SER A 220 GLY A 237 1 ? 18 
HELX_P HELX_P11 AB2 TYR A 242 ? SER A 250 ? TYR A 242 SER A 250 1 ? 9  
HELX_P HELX_P12 AB3 GLU A 252 ? THR A 257 ? GLU A 252 THR A 257 1 ? 6  
HELX_P HELX_P13 AB4 THR A 287 ? LEU A 297 ? THR A 287 LEU A 297 1 ? 11 
HELX_P HELX_P14 AB5 GLY A 303 ? LYS A 323 ? GLY A 303 LYS A 323 1 ? 21 
HELX_P HELX_P15 AB6 TYR A 361 ? GLY A 377 ? TYR A 361 GLY A 377 1 ? 17 
HELX_P HELX_P16 AB7 TRP A 378 ? TYR A 393 ? TRP A 378 TYR A 393 1 ? 16 
HELX_P HELX_P17 AB8 PRO A 394 ? ASN A 399 ? PRO A 394 ASN A 399 1 ? 6  
HELX_P HELX_P18 AB9 GLY A 427 ? GLU A 432 ? GLY A 427 GLU A 432 5 ? 6  
HELX_P HELX_P19 AC1 SER B 25  ? LEU B 34  ? SER B 25  LEU B 34  1 ? 10 
HELX_P HELX_P20 AC2 HIS B 38  ? SER B 58  ? HIS B 38  SER B 58  1 ? 21 
HELX_P HELX_P21 AC3 LYS B 62  ? ALA B 76  ? LYS B 62  ALA B 76  1 ? 15 
HELX_P HELX_P22 AC4 VAL B 77  ? MET B 81  ? VAL B 77  MET B 81  5 ? 5  
HELX_P HELX_P23 AC5 ALA B 111 ? GLU B 113 ? ALA B 111 GLU B 113 5 ? 3  
HELX_P HELX_P24 AC6 GLU B 137 ? GLN B 151 ? GLU B 137 GLN B 151 1 ? 15 
HELX_P HELX_P25 AC7 SER B 157 ? LEU B 167 ? SER B 157 LEU B 167 1 ? 11 
HELX_P HELX_P26 AC8 ASP B 170 ? GLN B 177 ? ASP B 170 GLN B 177 1 ? 8  
HELX_P HELX_P27 AC9 GLN B 177 ? ALA B 182 ? GLN B 177 ALA B 182 1 ? 6  
HELX_P HELX_P28 AD1 PRO B 210 ? MET B 217 ? PRO B 210 MET B 217 1 ? 8  
HELX_P HELX_P29 AD2 SER B 220 ? GLY B 237 ? SER B 220 GLY B 237 1 ? 18 
HELX_P HELX_P30 AD3 TYR B 242 ? SER B 250 ? TYR B 242 SER B 250 1 ? 9  
HELX_P HELX_P31 AD4 GLU B 252 ? THR B 257 ? GLU B 252 THR B 257 1 ? 6  
HELX_P HELX_P32 AD5 THR B 287 ? LEU B 297 ? THR B 287 LEU B 297 1 ? 11 
HELX_P HELX_P33 AD6 GLU B 305 ? LYS B 323 ? GLU B 305 LYS B 323 1 ? 19 
HELX_P HELX_P34 AD7 TYR B 361 ? GLY B 377 ? TYR B 361 GLY B 377 1 ? 17 
HELX_P HELX_P35 AD8 TRP B 378 ? TYR B 393 ? TRP B 378 TYR B 393 1 ? 16 
HELX_P HELX_P36 AD9 PRO B 394 ? ASN B 399 ? PRO B 394 ASN B 399 1 ? 6  
HELX_P HELX_P37 AE1 GLY B 427 ? GLU B 432 ? GLY B 427 GLU B 432 5 ? 6  
HELX_P HELX_P38 AE2 SER C 25  ? LEU C 34  ? SER C 25  LEU C 34  1 ? 10 
HELX_P HELX_P39 AE3 HIS C 38  ? SER C 58  ? HIS C 38  SER C 58  1 ? 21 
HELX_P HELX_P40 AE4 LYS C 62  ? ALA C 76  ? LYS C 62  ALA C 76  1 ? 15 
HELX_P HELX_P41 AE5 VAL C 77  ? MET C 81  ? VAL C 77  MET C 81  5 ? 5  
HELX_P HELX_P42 AE6 GLU C 137 ? GLN C 151 ? GLU C 137 GLN C 151 1 ? 15 
HELX_P HELX_P43 AE7 SER C 157 ? LEU C 167 ? SER C 157 LEU C 167 1 ? 11 
HELX_P HELX_P44 AE8 ASP C 170 ? GLN C 177 ? ASP C 170 GLN C 177 1 ? 8  
HELX_P HELX_P45 AE9 GLN C 177 ? ALA C 182 ? GLN C 177 ALA C 182 1 ? 6  
HELX_P HELX_P46 AF1 PRO C 210 ? MET C 217 ? PRO C 210 MET C 217 1 ? 8  
HELX_P HELX_P47 AF2 SER C 220 ? GLY C 237 ? SER C 220 GLY C 237 1 ? 18 
HELX_P HELX_P48 AF3 TYR C 242 ? SER C 250 ? TYR C 242 SER C 250 1 ? 9  
HELX_P HELX_P49 AF4 GLU C 252 ? THR C 257 ? GLU C 252 THR C 257 1 ? 6  
HELX_P HELX_P50 AF5 THR C 287 ? LEU C 297 ? THR C 287 LEU C 297 1 ? 11 
HELX_P HELX_P51 AF6 GLY C 303 ? LYS C 323 ? GLY C 303 LYS C 323 1 ? 21 
HELX_P HELX_P52 AF7 TYR C 361 ? GLY C 377 ? TYR C 361 GLY C 377 1 ? 17 
HELX_P HELX_P53 AF8 TRP C 378 ? TYR C 393 ? TRP C 378 TYR C 393 1 ? 16 
HELX_P HELX_P54 AF9 PRO C 394 ? ASN C 399 ? PRO C 394 ASN C 399 1 ? 6  
HELX_P HELX_P55 AG1 GLY C 427 ? GLU C 432 ? GLY C 427 GLU C 432 5 ? 6  
HELX_P HELX_P56 AG2 SER D 25  ? LEU D 34  ? SER D 25  LEU D 34  1 ? 10 
HELX_P HELX_P57 AG3 HIS D 38  ? SER D 58  ? HIS D 38  SER D 58  1 ? 21 
HELX_P HELX_P58 AG4 LYS D 62  ? ALA D 76  ? LYS D 62  ALA D 76  1 ? 15 
HELX_P HELX_P59 AG5 VAL D 77  ? MET D 81  ? VAL D 77  MET D 81  5 ? 5  
HELX_P HELX_P60 AG6 GLU D 137 ? GLN D 151 ? GLU D 137 GLN D 151 1 ? 15 
HELX_P HELX_P61 AG7 SER D 157 ? LEU D 167 ? SER D 157 LEU D 167 1 ? 11 
HELX_P HELX_P62 AG8 ASP D 170 ? GLN D 177 ? ASP D 170 GLN D 177 1 ? 8  
HELX_P HELX_P63 AG9 GLN D 177 ? ALA D 182 ? GLN D 177 ALA D 182 1 ? 6  
HELX_P HELX_P64 AH1 PRO D 210 ? MET D 217 ? PRO D 210 MET D 217 1 ? 8  
HELX_P HELX_P65 AH2 SER D 220 ? GLY D 237 ? SER D 220 GLY D 237 1 ? 18 
HELX_P HELX_P66 AH3 TYR D 242 ? SER D 250 ? TYR D 242 SER D 250 1 ? 9  
HELX_P HELX_P67 AH4 GLU D 252 ? THR D 257 ? GLU D 252 THR D 257 1 ? 6  
HELX_P HELX_P68 AH5 THR D 287 ? LEU D 297 ? THR D 287 LEU D 297 1 ? 11 
HELX_P HELX_P69 AH6 GLY D 303 ? LYS D 323 ? GLY D 303 LYS D 323 1 ? 21 
HELX_P HELX_P70 AH7 TYR D 361 ? GLY D 377 ? TYR D 361 GLY D 377 1 ? 17 
HELX_P HELX_P71 AH8 TRP D 378 ? TYR D 393 ? TRP D 378 TYR D 393 1 ? 16 
HELX_P HELX_P72 AH9 PRO D 394 ? ASN D 399 ? PRO D 394 ASN D 399 1 ? 6  
HELX_P HELX_P73 AI1 GLY D 427 ? GLU D 432 ? GLY D 427 GLU D 432 5 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 12 ? 
AA2 ? 12 ? 
AA3 ? 12 ? 
AA4 ? 12 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  3  ? anti-parallel 
AA1 1  12 ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 2  12 ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 8  10 ? anti-parallel 
AA1 10 11 ? anti-parallel 
AA1 11 12 ? anti-parallel 
AA2 1  3  ? anti-parallel 
AA2 1  12 ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 2  12 ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA2 6  7  ? anti-parallel 
AA2 7  8  ? anti-parallel 
AA2 8  9  ? anti-parallel 
AA2 8  10 ? anti-parallel 
AA2 10 11 ? anti-parallel 
AA2 11 12 ? anti-parallel 
AA3 1  3  ? anti-parallel 
AA3 1  12 ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 2  12 ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA3 5  6  ? anti-parallel 
AA3 6  7  ? anti-parallel 
AA3 7  8  ? anti-parallel 
AA3 8  9  ? anti-parallel 
AA3 8  10 ? anti-parallel 
AA3 10 11 ? anti-parallel 
AA3 11 12 ? anti-parallel 
AA4 1  3  ? anti-parallel 
AA4 1  12 ? anti-parallel 
AA4 2  3  ? anti-parallel 
AA4 2  12 ? anti-parallel 
AA4 3  4  ? anti-parallel 
AA4 4  5  ? anti-parallel 
AA4 5  6  ? anti-parallel 
AA4 6  7  ? anti-parallel 
AA4 7  8  ? anti-parallel 
AA4 8  9  ? anti-parallel 
AA4 8  10 ? anti-parallel 
AA4 10 11 ? anti-parallel 
AA4 11 12 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLU A 104 ? ALA A 105 ? GLU A 104 ALA A 105 
AA1 2  ASN A 108 ? GLN A 110 ? ASN A 108 GLN A 110 
AA1 3  SER A 114 ? ILE A 121 ? SER A 114 ILE A 121 
AA1 4  VAL A 191 ? MET A 196 ? VAL A 191 MET A 196 
AA1 5  THR A 203 ? PHE A 208 ? THR A 203 PHE A 208 
AA1 6  MET A 258 ? ASP A 268 ? MET A 258 ASP A 268 
AA1 7  ILE A 277 ? VAL A 285 ? ILE A 277 VAL A 285 
AA1 8  ASN A 334 ? MET A 342 ? ASN A 334 MET A 342 
AA1 9  VAL A 349 ? ALA A 350 ? VAL A 349 ALA A 350 
AA1 10 LEU A 353 ? THR A 356 ? LEU A 353 THR A 356 
AA1 11 TYR A 406 ? LEU A 411 ? TYR A 406 LEU A 411 
AA1 12 ILE A 420 ? THR A 424 ? ILE A 420 THR A 424 
AA2 1  GLU B 104 ? ALA B 105 ? GLU B 104 ALA B 105 
AA2 2  ASN B 108 ? GLN B 110 ? ASN B 108 GLN B 110 
AA2 3  SER B 114 ? ILE B 121 ? SER B 114 ILE B 121 
AA2 4  VAL B 191 ? MET B 196 ? VAL B 191 MET B 196 
AA2 5  THR B 203 ? PHE B 208 ? THR B 203 PHE B 208 
AA2 6  MET B 258 ? ASP B 268 ? MET B 258 ASP B 268 
AA2 7  ARG B 276 ? VAL B 285 ? ARG B 276 VAL B 285 
AA2 8  ASN B 334 ? SER B 343 ? ASN B 334 SER B 343 
AA2 9  VAL B 349 ? ALA B 350 ? VAL B 349 ALA B 350 
AA2 10 LEU B 353 ? THR B 356 ? LEU B 353 THR B 356 
AA2 11 TYR B 406 ? LEU B 411 ? TYR B 406 LEU B 411 
AA2 12 ILE B 420 ? THR B 424 ? ILE B 420 THR B 424 
AA3 1  GLU C 104 ? ALA C 105 ? GLU C 104 ALA C 105 
AA3 2  ASN C 108 ? GLN C 110 ? ASN C 108 GLN C 110 
AA3 3  SER C 114 ? ILE C 121 ? SER C 114 ILE C 121 
AA3 4  VAL C 191 ? MET C 196 ? VAL C 191 MET C 196 
AA3 5  THR C 203 ? PHE C 208 ? THR C 203 PHE C 208 
AA3 6  MET C 258 ? ASP C 268 ? MET C 258 ASP C 268 
AA3 7  ILE C 277 ? VAL C 285 ? ILE C 277 VAL C 285 
AA3 8  ASN C 334 ? MET C 342 ? ASN C 334 MET C 342 
AA3 9  VAL C 349 ? ALA C 350 ? VAL C 349 ALA C 350 
AA3 10 LEU C 353 ? THR C 356 ? LEU C 353 THR C 356 
AA3 11 TYR C 406 ? LEU C 411 ? TYR C 406 LEU C 411 
AA3 12 ILE C 420 ? THR C 424 ? ILE C 420 THR C 424 
AA4 1  GLU D 104 ? ALA D 105 ? GLU D 104 ALA D 105 
AA4 2  ASN D 108 ? GLN D 110 ? ASN D 108 GLN D 110 
AA4 3  SER D 114 ? ILE D 121 ? SER D 114 ILE D 121 
AA4 4  VAL D 191 ? MET D 196 ? VAL D 191 MET D 196 
AA4 5  THR D 203 ? PHE D 208 ? THR D 203 PHE D 208 
AA4 6  MET D 258 ? ASP D 268 ? MET D 258 ASP D 268 
AA4 7  ILE D 277 ? VAL D 285 ? ILE D 277 VAL D 285 
AA4 8  ASN D 334 ? MET D 342 ? ASN D 334 MET D 342 
AA4 9  VAL D 349 ? ALA D 350 ? VAL D 349 ALA D 350 
AA4 10 LEU D 353 ? THR D 356 ? LEU D 353 THR D 356 
AA4 11 TYR D 406 ? LEU D 411 ? TYR D 406 LEU D 411 
AA4 12 ILE D 420 ? THR D 424 ? ILE D 420 THR D 424 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  3  N GLU A 104 ? N GLU A 104 O THR A 120 ? O THR A 120 
AA1 1  12 N ALA A 105 ? N ALA A 105 O THR A 424 ? O THR A 424 
AA1 2  3  N ASN A 108 ? N ASN A 108 O MET A 116 ? O MET A 116 
AA1 2  12 N TYR A 109 ? N TYR A 109 O ILE A 420 ? O ILE A 420 
AA1 3  4  N PHE A 119 ? N PHE A 119 O LEU A 194 ? O LEU A 194 
AA1 4  5  N ASP A 195 ? N ASP A 195 O THR A 203 ? O THR A 203 
AA1 5  6  N PHE A 208 ? N PHE A 208 O LEU A 265 ? O LEU A 265 
AA1 6  7  N SER A 266 ? N SER A 266 O LYS A 278 ? O LYS A 278 
AA1 7  8  N THR A 281 ? N THR A 281 O ILE A 338 ? O ILE A 338 
AA1 8  9  N GLU A 341 ? N GLU A 341 O ALA A 350 ? O ALA A 350 
AA1 8  10 N HIS A 335 ? N HIS A 335 O THR A 356 ? O THR A 356 
AA1 10 11 N LEU A 353 ? N LEU A 353 O LEU A 411 ? O LEU A 411 
AA1 11 12 N SER A 410 ? N SER A 410 O THR A 421 ? O THR A 421 
AA2 1  3  N GLU B 104 ? N GLU B 104 O THR B 120 ? O THR B 120 
AA2 1  12 N ALA B 105 ? N ALA B 105 O THR B 424 ? O THR B 424 
AA2 2  3  N ASN B 108 ? N ASN B 108 O MET B 116 ? O MET B 116 
AA2 2  12 N TYR B 109 ? N TYR B 109 O ILE B 420 ? O ILE B 420 
AA2 3  4  N PHE B 119 ? N PHE B 119 O LEU B 194 ? O LEU B 194 
AA2 4  5  N ASP B 195 ? N ASP B 195 O THR B 203 ? O THR B 203 
AA2 5  6  N PHE B 208 ? N PHE B 208 O LEU B 265 ? O LEU B 265 
AA2 6  7  N SER B 266 ? N SER B 266 O LYS B 278 ? O LYS B 278 
AA2 7  8  N THR B 281 ? N THR B 281 O ILE B 338 ? O ILE B 338 
AA2 8  9  N GLU B 341 ? N GLU B 341 O ALA B 350 ? O ALA B 350 
AA2 8  10 N GLN B 337 ? N GLN B 337 O TYR B 354 ? O TYR B 354 
AA2 10 11 N LEU B 353 ? N LEU B 353 O LEU B 411 ? O LEU B 411 
AA2 11 12 N SER B 410 ? N SER B 410 O THR B 421 ? O THR B 421 
AA3 1  3  N GLU C 104 ? N GLU C 104 O THR C 120 ? O THR C 120 
AA3 1  12 N ALA C 105 ? N ALA C 105 O THR C 424 ? O THR C 424 
AA3 2  3  N ASN C 108 ? N ASN C 108 O MET C 116 ? O MET C 116 
AA3 2  12 N TYR C 109 ? N TYR C 109 O ILE C 420 ? O ILE C 420 
AA3 3  4  N PHE C 119 ? N PHE C 119 O LEU C 194 ? O LEU C 194 
AA3 4  5  N ASP C 195 ? N ASP C 195 O THR C 203 ? O THR C 203 
AA3 5  6  N PHE C 208 ? N PHE C 208 O LEU C 265 ? O LEU C 265 
AA3 6  7  N SER C 266 ? N SER C 266 O LYS C 278 ? O LYS C 278 
AA3 7  8  N THR C 281 ? N THR C 281 O ILE C 338 ? O ILE C 338 
AA3 8  9  N GLU C 341 ? N GLU C 341 O ALA C 350 ? O ALA C 350 
AA3 8  10 N HIS C 335 ? N HIS C 335 O THR C 356 ? O THR C 356 
AA3 10 11 N LEU C 353 ? N LEU C 353 O LEU C 411 ? O LEU C 411 
AA3 11 12 N SER C 410 ? N SER C 410 O THR C 421 ? O THR C 421 
AA4 1  3  N GLU D 104 ? N GLU D 104 O THR D 120 ? O THR D 120 
AA4 1  12 N ALA D 105 ? N ALA D 105 O THR D 424 ? O THR D 424 
AA4 2  3  N ASN D 108 ? N ASN D 108 O MET D 116 ? O MET D 116 
AA4 2  12 N TYR D 109 ? N TYR D 109 O ILE D 420 ? O ILE D 420 
AA4 3  4  N PHE D 119 ? N PHE D 119 O LEU D 194 ? O LEU D 194 
AA4 4  5  N ASP D 195 ? N ASP D 195 O THR D 203 ? O THR D 203 
AA4 5  6  N PHE D 208 ? N PHE D 208 O LEU D 265 ? O LEU D 265 
AA4 6  7  N SER D 266 ? N SER D 266 O LYS D 278 ? O LYS D 278 
AA4 7  8  N THR D 281 ? N THR D 281 O ILE D 338 ? O ILE D 338 
AA4 8  9  N GLU D 341 ? N GLU D 341 O ALA D 350 ? O ALA D 350 
AA4 8  10 N HIS D 335 ? N HIS D 335 O THR D 356 ? O THR D 356 
AA4 10 11 N LEU D 353 ? N LEU D 353 O LEU D 411 ? O LEU D 411 
AA4 11 12 N SER D 410 ? N SER D 410 O THR D 421 ? O THR D 421 
# 
_pdbx_entry_details.entry_id                   9JHX 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O  A HIS 127 ? ? OG1 A THR 130 ? ? 2.05 
2  1 O  C HIS 127 ? ? OG1 C THR 130 ? ? 2.05 
3  1 O  D HIS 127 ? ? OG1 D THR 130 ? ? 2.06 
4  1 O  B HIS 127 ? ? OG1 B THR 130 ? ? 2.06 
5  1 O  C ILE 54  ? ? OG  C SER 58  ? ? 2.15 
6  1 O  D ILE 54  ? ? OG  D SER 58  ? ? 2.16 
7  1 O  A ILE 54  ? ? OG  A SER 58  ? ? 2.16 
8  1 OH B TYR 419 ? ? O6  B DST 501 ? ? 2.17 
9  1 OG A SER 25  ? ? OD2 A ASP 28  ? ? 2.17 
10 1 OH A TYR 419 ? ? O6  A DST 501 ? ? 2.17 
11 1 OG C SER 25  ? ? OD2 C ASP 28  ? ? 2.17 
12 1 OG D SER 25  ? ? OD2 D ASP 28  ? ? 2.17 
13 1 OH D TYR 419 ? ? O6  D DST 501 ? ? 2.17 
14 1 OH C TYR 419 ? ? O6  C DST 501 ? ? 2.17 
15 1 OG B SER 25  ? ? OD2 B ASP 28  ? ? 2.18 
16 1 O  B ILE 54  ? ? OG  B SER 58  ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN A 177 ? ? -105.25 40.58   
2  1 LYS A 187 ? ? -93.90  57.19   
3  1 ALA A 412 ? ? -170.45 133.60  
4  1 ALA B 89  ? ? 35.98   46.21   
5  1 GLN B 177 ? ? -105.16 41.48   
6  1 LYS B 187 ? ? -94.49  57.50   
7  1 ARG B 262 ? ? -100.28 61.77   
8  1 LYS B 352 ? ? -160.63 116.83  
9  1 LYS B 414 ? ? -122.69 -169.30 
10 1 GLN C 177 ? ? -105.21 40.59   
11 1 LYS C 187 ? ? -93.91  57.23   
12 1 ALA C 412 ? ? -170.45 133.66  
13 1 GLN D 177 ? ? -105.21 40.52   
14 1 LYS D 187 ? ? -93.96  57.19   
15 1 ALA D 412 ? ? -170.44 133.66  
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 ALA A 105 ? ? SER A 106 ? ? -146.12 
2 1 ALA B 105 ? ? SER B 106 ? ? -146.54 
3 1 ALA C 105 ? ? SER C 106 ? ? -146.11 
4 1 ALA D 105 ? ? SER D 106 ? ? -146.12 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JHX 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JHX 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.86 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               178786 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Versatile Aromatic Prenyltransferase auraA mutant-Y207A in complex with DMSPP' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JHX 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             600 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9JHX 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JHX 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A THR 2   ? A THR 2   
3  1 Y 1 A VAL 3   ? A VAL 3   
4  1 Y 1 A GLU 4   ? A GLU 4   
5  1 Y 1 A HIS 5   ? A HIS 5   
6  1 Y 1 A ALA 6   ? A ALA 6   
7  1 Y 1 A GLN 7   ? A GLN 7   
8  1 Y 1 A LEU 8   ? A LEU 8   
9  1 Y 1 A THR 9   ? A THR 9   
10 1 Y 1 A SER 10  ? A SER 10  
11 1 Y 1 A ASN 11  ? A ASN 11  
12 1 Y 1 A ASP 12  ? A ASP 12  
13 1 Y 1 A LEU 13  ? A LEU 13  
14 1 Y 1 A LEU 14  ? A LEU 14  
15 1 Y 1 A VAL 15  ? A VAL 15  
16 1 Y 1 A LYS 16  ? A LYS 16  
17 1 Y 1 A SER 17  ? A SER 17  
18 1 Y 1 A ILE 18  ? A ILE 18  
19 1 Y 1 A SER 19  ? A SER 19  
20 1 Y 1 A SER 20  ? A SER 20  
21 1 Y 1 A SER 21  ? A SER 21  
22 1 Y 1 A PRO 22  ? A PRO 22  
23 1 Y 1 A LYS 433 ? A LYS 433 
24 1 Y 1 A ALA 434 ? A ALA 434 
25 1 Y 1 B MET 1   ? B MET 1   
26 1 Y 1 B THR 2   ? B THR 2   
27 1 Y 1 B VAL 3   ? B VAL 3   
28 1 Y 1 B GLU 4   ? B GLU 4   
29 1 Y 1 B HIS 5   ? B HIS 5   
30 1 Y 1 B ALA 6   ? B ALA 6   
31 1 Y 1 B GLN 7   ? B GLN 7   
32 1 Y 1 B LEU 8   ? B LEU 8   
33 1 Y 1 B THR 9   ? B THR 9   
34 1 Y 1 B SER 10  ? B SER 10  
35 1 Y 1 B ASN 11  ? B ASN 11  
36 1 Y 1 B ASP 12  ? B ASP 12  
37 1 Y 1 B LEU 13  ? B LEU 13  
38 1 Y 1 B LEU 14  ? B LEU 14  
39 1 Y 1 B VAL 15  ? B VAL 15  
40 1 Y 1 B LYS 16  ? B LYS 16  
41 1 Y 1 B SER 17  ? B SER 17  
42 1 Y 1 B ILE 18  ? B ILE 18  
43 1 Y 1 B SER 19  ? B SER 19  
44 1 Y 1 B SER 20  ? B SER 20  
45 1 Y 1 B SER 21  ? B SER 21  
46 1 Y 1 B PRO 22  ? B PRO 22  
47 1 Y 1 B LYS 433 ? B LYS 433 
48 1 Y 1 B ALA 434 ? B ALA 434 
49 1 Y 1 C MET 1   ? C MET 1   
50 1 Y 1 C THR 2   ? C THR 2   
51 1 Y 1 C VAL 3   ? C VAL 3   
52 1 Y 1 C GLU 4   ? C GLU 4   
53 1 Y 1 C HIS 5   ? C HIS 5   
54 1 Y 1 C ALA 6   ? C ALA 6   
55 1 Y 1 C GLN 7   ? C GLN 7   
56 1 Y 1 C LEU 8   ? C LEU 8   
57 1 Y 1 C THR 9   ? C THR 9   
58 1 Y 1 C SER 10  ? C SER 10  
59 1 Y 1 C ASN 11  ? C ASN 11  
60 1 Y 1 C ASP 12  ? C ASP 12  
61 1 Y 1 C LEU 13  ? C LEU 13  
62 1 Y 1 C LEU 14  ? C LEU 14  
63 1 Y 1 C VAL 15  ? C VAL 15  
64 1 Y 1 C LYS 16  ? C LYS 16  
65 1 Y 1 C SER 17  ? C SER 17  
66 1 Y 1 C ILE 18  ? C ILE 18  
67 1 Y 1 C SER 19  ? C SER 19  
68 1 Y 1 C SER 20  ? C SER 20  
69 1 Y 1 C SER 21  ? C SER 21  
70 1 Y 1 C PRO 22  ? C PRO 22  
71 1 Y 1 C LYS 433 ? C LYS 433 
72 1 Y 1 C ALA 434 ? C ALA 434 
73 1 Y 1 D MET 1   ? D MET 1   
74 1 Y 1 D THR 2   ? D THR 2   
75 1 Y 1 D VAL 3   ? D VAL 3   
76 1 Y 1 D GLU 4   ? D GLU 4   
77 1 Y 1 D HIS 5   ? D HIS 5   
78 1 Y 1 D ALA 6   ? D ALA 6   
79 1 Y 1 D GLN 7   ? D GLN 7   
80 1 Y 1 D LEU 8   ? D LEU 8   
81 1 Y 1 D THR 9   ? D THR 9   
82 1 Y 1 D SER 10  ? D SER 10  
83 1 Y 1 D ASN 11  ? D ASN 11  
84 1 Y 1 D ASP 12  ? D ASP 12  
85 1 Y 1 D LEU 13  ? D LEU 13  
86 1 Y 1 D LEU 14  ? D LEU 14  
87 1 Y 1 D VAL 15  ? D VAL 15  
88 1 Y 1 D LYS 16  ? D LYS 16  
89 1 Y 1 D SER 17  ? D SER 17  
90 1 Y 1 D ILE 18  ? D ILE 18  
91 1 Y 1 D SER 19  ? D SER 19  
92 1 Y 1 D SER 20  ? D SER 20  
93 1 Y 1 D SER 21  ? D SER 21  
94 1 Y 1 D PRO 22  ? D PRO 22  
95 1 Y 1 D LYS 433 ? D LYS 433 
96 1 Y 1 D ALA 434 ? D ALA 434 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
DST O4   O N N 88  
DST P1   P N N 89  
DST O6   O N N 90  
DST O5   O N N 91  
DST O2   O N N 92  
DST P3   P N N 93  
DST O8   O N N 94  
DST O7   O N N 95  
DST S9   S N N 96  
DST C10  C N N 97  
DST C11  C N N 98  
DST C12  C N N 99  
DST C13  C N N 100 
DST C14  C N N 101 
DST HO4  H N N 102 
DST HO6  H N N 103 
DST HO8  H N N 104 
DST H101 H N N 105 
DST H102 H N N 106 
DST H111 H N N 107 
DST H131 H N N 108 
DST H132 H N N 109 
DST H133 H N N 110 
DST H141 H N N 111 
DST H142 H N N 112 
DST H143 H N N 113 
GLN N    N N N 114 
GLN CA   C N S 115 
GLN C    C N N 116 
GLN O    O N N 117 
GLN CB   C N N 118 
GLN CG   C N N 119 
GLN CD   C N N 120 
GLN OE1  O N N 121 
GLN NE2  N N N 122 
GLN OXT  O N N 123 
GLN H    H N N 124 
GLN H2   H N N 125 
GLN HA   H N N 126 
GLN HB2  H N N 127 
GLN HB3  H N N 128 
GLN HG2  H N N 129 
GLN HG3  H N N 130 
GLN HE21 H N N 131 
GLN HE22 H N N 132 
GLN HXT  H N N 133 
GLU N    N N N 134 
GLU CA   C N S 135 
GLU C    C N N 136 
GLU O    O N N 137 
GLU CB   C N N 138 
GLU CG   C N N 139 
GLU CD   C N N 140 
GLU OE1  O N N 141 
GLU OE2  O N N 142 
GLU OXT  O N N 143 
GLU H    H N N 144 
GLU H2   H N N 145 
GLU HA   H N N 146 
GLU HB2  H N N 147 
GLU HB3  H N N 148 
GLU HG2  H N N 149 
GLU HG3  H N N 150 
GLU HE2  H N N 151 
GLU HXT  H N N 152 
GLY N    N N N 153 
GLY CA   C N N 154 
GLY C    C N N 155 
GLY O    O N N 156 
GLY OXT  O N N 157 
GLY H    H N N 158 
GLY H2   H N N 159 
GLY HA2  H N N 160 
GLY HA3  H N N 161 
GLY HXT  H N N 162 
HIS N    N N N 163 
HIS CA   C N S 164 
HIS C    C N N 165 
HIS O    O N N 166 
HIS CB   C N N 167 
HIS CG   C Y N 168 
HIS ND1  N Y N 169 
HIS CD2  C Y N 170 
HIS CE1  C Y N 171 
HIS NE2  N Y N 172 
HIS OXT  O N N 173 
HIS H    H N N 174 
HIS H2   H N N 175 
HIS HA   H N N 176 
HIS HB2  H N N 177 
HIS HB3  H N N 178 
HIS HD1  H N N 179 
HIS HD2  H N N 180 
HIS HE1  H N N 181 
HIS HE2  H N N 182 
HIS HXT  H N N 183 
ILE N    N N N 184 
ILE CA   C N S 185 
ILE C    C N N 186 
ILE O    O N N 187 
ILE CB   C N S 188 
ILE CG1  C N N 189 
ILE CG2  C N N 190 
ILE CD1  C N N 191 
ILE OXT  O N N 192 
ILE H    H N N 193 
ILE H2   H N N 194 
ILE HA   H N N 195 
ILE HB   H N N 196 
ILE HG12 H N N 197 
ILE HG13 H N N 198 
ILE HG21 H N N 199 
ILE HG22 H N N 200 
ILE HG23 H N N 201 
ILE HD11 H N N 202 
ILE HD12 H N N 203 
ILE HD13 H N N 204 
ILE HXT  H N N 205 
LEU N    N N N 206 
LEU CA   C N S 207 
LEU C    C N N 208 
LEU O    O N N 209 
LEU CB   C N N 210 
LEU CG   C N N 211 
LEU CD1  C N N 212 
LEU CD2  C N N 213 
LEU OXT  O N N 214 
LEU H    H N N 215 
LEU H2   H N N 216 
LEU HA   H N N 217 
LEU HB2  H N N 218 
LEU HB3  H N N 219 
LEU HG   H N N 220 
LEU HD11 H N N 221 
LEU HD12 H N N 222 
LEU HD13 H N N 223 
LEU HD21 H N N 224 
LEU HD22 H N N 225 
LEU HD23 H N N 226 
LEU HXT  H N N 227 
LYS N    N N N 228 
LYS CA   C N S 229 
LYS C    C N N 230 
LYS O    O N N 231 
LYS CB   C N N 232 
LYS CG   C N N 233 
LYS CD   C N N 234 
LYS CE   C N N 235 
LYS NZ   N N N 236 
LYS OXT  O N N 237 
LYS H    H N N 238 
LYS H2   H N N 239 
LYS HA   H N N 240 
LYS HB2  H N N 241 
LYS HB3  H N N 242 
LYS HG2  H N N 243 
LYS HG3  H N N 244 
LYS HD2  H N N 245 
LYS HD3  H N N 246 
LYS HE2  H N N 247 
LYS HE3  H N N 248 
LYS HZ1  H N N 249 
LYS HZ2  H N N 250 
LYS HZ3  H N N 251 
LYS HXT  H N N 252 
MET N    N N N 253 
MET CA   C N S 254 
MET C    C N N 255 
MET O    O N N 256 
MET CB   C N N 257 
MET CG   C N N 258 
MET SD   S N N 259 
MET CE   C N N 260 
MET OXT  O N N 261 
MET H    H N N 262 
MET H2   H N N 263 
MET HA   H N N 264 
MET HB2  H N N 265 
MET HB3  H N N 266 
MET HG2  H N N 267 
MET HG3  H N N 268 
MET HE1  H N N 269 
MET HE2  H N N 270 
MET HE3  H N N 271 
MET HXT  H N N 272 
PHE N    N N N 273 
PHE CA   C N S 274 
PHE C    C N N 275 
PHE O    O N N 276 
PHE CB   C N N 277 
PHE CG   C Y N 278 
PHE CD1  C Y N 279 
PHE CD2  C Y N 280 
PHE CE1  C Y N 281 
PHE CE2  C Y N 282 
PHE CZ   C Y N 283 
PHE OXT  O N N 284 
PHE H    H N N 285 
PHE H2   H N N 286 
PHE HA   H N N 287 
PHE HB2  H N N 288 
PHE HB3  H N N 289 
PHE HD1  H N N 290 
PHE HD2  H N N 291 
PHE HE1  H N N 292 
PHE HE2  H N N 293 
PHE HZ   H N N 294 
PHE HXT  H N N 295 
PRO N    N N N 296 
PRO CA   C N S 297 
PRO C    C N N 298 
PRO O    O N N 299 
PRO CB   C N N 300 
PRO CG   C N N 301 
PRO CD   C N N 302 
PRO OXT  O N N 303 
PRO H    H N N 304 
PRO HA   H N N 305 
PRO HB2  H N N 306 
PRO HB3  H N N 307 
PRO HG2  H N N 308 
PRO HG3  H N N 309 
PRO HD2  H N N 310 
PRO HD3  H N N 311 
PRO HXT  H N N 312 
SER N    N N N 313 
SER CA   C N S 314 
SER C    C N N 315 
SER O    O N N 316 
SER CB   C N N 317 
SER OG   O N N 318 
SER OXT  O N N 319 
SER H    H N N 320 
SER H2   H N N 321 
SER HA   H N N 322 
SER HB2  H N N 323 
SER HB3  H N N 324 
SER HG   H N N 325 
SER HXT  H N N 326 
THR N    N N N 327 
THR CA   C N S 328 
THR C    C N N 329 
THR O    O N N 330 
THR CB   C N R 331 
THR OG1  O N N 332 
THR CG2  C N N 333 
THR OXT  O N N 334 
THR H    H N N 335 
THR H2   H N N 336 
THR HA   H N N 337 
THR HB   H N N 338 
THR HG1  H N N 339 
THR HG21 H N N 340 
THR HG22 H N N 341 
THR HG23 H N N 342 
THR HXT  H N N 343 
TRP N    N N N 344 
TRP CA   C N S 345 
TRP C    C N N 346 
TRP O    O N N 347 
TRP CB   C N N 348 
TRP CG   C Y N 349 
TRP CD1  C Y N 350 
TRP CD2  C Y N 351 
TRP NE1  N Y N 352 
TRP CE2  C Y N 353 
TRP CE3  C Y N 354 
TRP CZ2  C Y N 355 
TRP CZ3  C Y N 356 
TRP CH2  C Y N 357 
TRP OXT  O N N 358 
TRP H    H N N 359 
TRP H2   H N N 360 
TRP HA   H N N 361 
TRP HB2  H N N 362 
TRP HB3  H N N 363 
TRP HD1  H N N 364 
TRP HE1  H N N 365 
TRP HE3  H N N 366 
TRP HZ2  H N N 367 
TRP HZ3  H N N 368 
TRP HH2  H N N 369 
TRP HXT  H N N 370 
TYR N    N N N 371 
TYR CA   C N S 372 
TYR C    C N N 373 
TYR O    O N N 374 
TYR CB   C N N 375 
TYR CG   C Y N 376 
TYR CD1  C Y N 377 
TYR CD2  C Y N 378 
TYR CE1  C Y N 379 
TYR CE2  C Y N 380 
TYR CZ   C Y N 381 
TYR OH   O N N 382 
TYR OXT  O N N 383 
TYR H    H N N 384 
TYR H2   H N N 385 
TYR HA   H N N 386 
TYR HB2  H N N 387 
TYR HB3  H N N 388 
TYR HD1  H N N 389 
TYR HD2  H N N 390 
TYR HE1  H N N 391 
TYR HE2  H N N 392 
TYR HH   H N N 393 
TYR HXT  H N N 394 
VAL N    N N N 395 
VAL CA   C N S 396 
VAL C    C N N 397 
VAL O    O N N 398 
VAL CB   C N N 399 
VAL CG1  C N N 400 
VAL CG2  C N N 401 
VAL OXT  O N N 402 
VAL H    H N N 403 
VAL H2   H N N 404 
VAL HA   H N N 405 
VAL HB   H N N 406 
VAL HG11 H N N 407 
VAL HG12 H N N 408 
VAL HG13 H N N 409 
VAL HG21 H N N 410 
VAL HG22 H N N 411 
VAL HG23 H N N 412 
VAL HXT  H N N 413 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
DST O4  P1   sing N N 83  
DST O4  HO4  sing N N 84  
DST P1  O6   sing N N 85  
DST P1  O5   doub N N 86  
DST P1  O2   sing N N 87  
DST O6  HO6  sing N N 88  
DST O2  P3   sing N N 89  
DST P3  O8   sing N N 90  
DST P3  O7   doub N N 91  
DST P3  S9   sing N N 92  
DST O8  HO8  sing N N 93  
DST S9  C10  sing N N 94  
DST C10 C11  sing N N 95  
DST C10 H101 sing N N 96  
DST C10 H102 sing N N 97  
DST C11 C12  doub N N 98  
DST C11 H111 sing N N 99  
DST C12 C13  sing N N 100 
DST C12 C14  sing N N 101 
DST C13 H131 sing N N 102 
DST C13 H132 sing N N 103 
DST C13 H133 sing N N 104 
DST C14 H141 sing N N 105 
DST C14 H142 sing N N 106 
DST C14 H143 sing N N 107 
GLN N   CA   sing N N 108 
GLN N   H    sing N N 109 
GLN N   H2   sing N N 110 
GLN CA  C    sing N N 111 
GLN CA  CB   sing N N 112 
GLN CA  HA   sing N N 113 
GLN C   O    doub N N 114 
GLN C   OXT  sing N N 115 
GLN CB  CG   sing N N 116 
GLN CB  HB2  sing N N 117 
GLN CB  HB3  sing N N 118 
GLN CG  CD   sing N N 119 
GLN CG  HG2  sing N N 120 
GLN CG  HG3  sing N N 121 
GLN CD  OE1  doub N N 122 
GLN CD  NE2  sing N N 123 
GLN NE2 HE21 sing N N 124 
GLN NE2 HE22 sing N N 125 
GLN OXT HXT  sing N N 126 
GLU N   CA   sing N N 127 
GLU N   H    sing N N 128 
GLU N   H2   sing N N 129 
GLU CA  C    sing N N 130 
GLU CA  CB   sing N N 131 
GLU CA  HA   sing N N 132 
GLU C   O    doub N N 133 
GLU C   OXT  sing N N 134 
GLU CB  CG   sing N N 135 
GLU CB  HB2  sing N N 136 
GLU CB  HB3  sing N N 137 
GLU CG  CD   sing N N 138 
GLU CG  HG2  sing N N 139 
GLU CG  HG3  sing N N 140 
GLU CD  OE1  doub N N 141 
GLU CD  OE2  sing N N 142 
GLU OE2 HE2  sing N N 143 
GLU OXT HXT  sing N N 144 
GLY N   CA   sing N N 145 
GLY N   H    sing N N 146 
GLY N   H2   sing N N 147 
GLY CA  C    sing N N 148 
GLY CA  HA2  sing N N 149 
GLY CA  HA3  sing N N 150 
GLY C   O    doub N N 151 
GLY C   OXT  sing N N 152 
GLY OXT HXT  sing N N 153 
HIS N   CA   sing N N 154 
HIS N   H    sing N N 155 
HIS N   H2   sing N N 156 
HIS CA  C    sing N N 157 
HIS CA  CB   sing N N 158 
HIS CA  HA   sing N N 159 
HIS C   O    doub N N 160 
HIS C   OXT  sing N N 161 
HIS CB  CG   sing N N 162 
HIS CB  HB2  sing N N 163 
HIS CB  HB3  sing N N 164 
HIS CG  ND1  sing Y N 165 
HIS CG  CD2  doub Y N 166 
HIS ND1 CE1  doub Y N 167 
HIS ND1 HD1  sing N N 168 
HIS CD2 NE2  sing Y N 169 
HIS CD2 HD2  sing N N 170 
HIS CE1 NE2  sing Y N 171 
HIS CE1 HE1  sing N N 172 
HIS NE2 HE2  sing N N 173 
HIS OXT HXT  sing N N 174 
ILE N   CA   sing N N 175 
ILE N   H    sing N N 176 
ILE N   H2   sing N N 177 
ILE CA  C    sing N N 178 
ILE CA  CB   sing N N 179 
ILE CA  HA   sing N N 180 
ILE C   O    doub N N 181 
ILE C   OXT  sing N N 182 
ILE CB  CG1  sing N N 183 
ILE CB  CG2  sing N N 184 
ILE CB  HB   sing N N 185 
ILE CG1 CD1  sing N N 186 
ILE CG1 HG12 sing N N 187 
ILE CG1 HG13 sing N N 188 
ILE CG2 HG21 sing N N 189 
ILE CG2 HG22 sing N N 190 
ILE CG2 HG23 sing N N 191 
ILE CD1 HD11 sing N N 192 
ILE CD1 HD12 sing N N 193 
ILE CD1 HD13 sing N N 194 
ILE OXT HXT  sing N N 195 
LEU N   CA   sing N N 196 
LEU N   H    sing N N 197 
LEU N   H2   sing N N 198 
LEU CA  C    sing N N 199 
LEU CA  CB   sing N N 200 
LEU CA  HA   sing N N 201 
LEU C   O    doub N N 202 
LEU C   OXT  sing N N 203 
LEU CB  CG   sing N N 204 
LEU CB  HB2  sing N N 205 
LEU CB  HB3  sing N N 206 
LEU CG  CD1  sing N N 207 
LEU CG  CD2  sing N N 208 
LEU CG  HG   sing N N 209 
LEU CD1 HD11 sing N N 210 
LEU CD1 HD12 sing N N 211 
LEU CD1 HD13 sing N N 212 
LEU CD2 HD21 sing N N 213 
LEU CD2 HD22 sing N N 214 
LEU CD2 HD23 sing N N 215 
LEU OXT HXT  sing N N 216 
LYS N   CA   sing N N 217 
LYS N   H    sing N N 218 
LYS N   H2   sing N N 219 
LYS CA  C    sing N N 220 
LYS CA  CB   sing N N 221 
LYS CA  HA   sing N N 222 
LYS C   O    doub N N 223 
LYS C   OXT  sing N N 224 
LYS CB  CG   sing N N 225 
LYS CB  HB2  sing N N 226 
LYS CB  HB3  sing N N 227 
LYS CG  CD   sing N N 228 
LYS CG  HG2  sing N N 229 
LYS CG  HG3  sing N N 230 
LYS CD  CE   sing N N 231 
LYS CD  HD2  sing N N 232 
LYS CD  HD3  sing N N 233 
LYS CE  NZ   sing N N 234 
LYS CE  HE2  sing N N 235 
LYS CE  HE3  sing N N 236 
LYS NZ  HZ1  sing N N 237 
LYS NZ  HZ2  sing N N 238 
LYS NZ  HZ3  sing N N 239 
LYS OXT HXT  sing N N 240 
MET N   CA   sing N N 241 
MET N   H    sing N N 242 
MET N   H2   sing N N 243 
MET CA  C    sing N N 244 
MET CA  CB   sing N N 245 
MET CA  HA   sing N N 246 
MET C   O    doub N N 247 
MET C   OXT  sing N N 248 
MET CB  CG   sing N N 249 
MET CB  HB2  sing N N 250 
MET CB  HB3  sing N N 251 
MET CG  SD   sing N N 252 
MET CG  HG2  sing N N 253 
MET CG  HG3  sing N N 254 
MET SD  CE   sing N N 255 
MET CE  HE1  sing N N 256 
MET CE  HE2  sing N N 257 
MET CE  HE3  sing N N 258 
MET OXT HXT  sing N N 259 
PHE N   CA   sing N N 260 
PHE N   H    sing N N 261 
PHE N   H2   sing N N 262 
PHE CA  C    sing N N 263 
PHE CA  CB   sing N N 264 
PHE CA  HA   sing N N 265 
PHE C   O    doub N N 266 
PHE C   OXT  sing N N 267 
PHE CB  CG   sing N N 268 
PHE CB  HB2  sing N N 269 
PHE CB  HB3  sing N N 270 
PHE CG  CD1  doub Y N 271 
PHE CG  CD2  sing Y N 272 
PHE CD1 CE1  sing Y N 273 
PHE CD1 HD1  sing N N 274 
PHE CD2 CE2  doub Y N 275 
PHE CD2 HD2  sing N N 276 
PHE CE1 CZ   doub Y N 277 
PHE CE1 HE1  sing N N 278 
PHE CE2 CZ   sing Y N 279 
PHE CE2 HE2  sing N N 280 
PHE CZ  HZ   sing N N 281 
PHE OXT HXT  sing N N 282 
PRO N   CA   sing N N 283 
PRO N   CD   sing N N 284 
PRO N   H    sing N N 285 
PRO CA  C    sing N N 286 
PRO CA  CB   sing N N 287 
PRO CA  HA   sing N N 288 
PRO C   O    doub N N 289 
PRO C   OXT  sing N N 290 
PRO CB  CG   sing N N 291 
PRO CB  HB2  sing N N 292 
PRO CB  HB3  sing N N 293 
PRO CG  CD   sing N N 294 
PRO CG  HG2  sing N N 295 
PRO CG  HG3  sing N N 296 
PRO CD  HD2  sing N N 297 
PRO CD  HD3  sing N N 298 
PRO OXT HXT  sing N N 299 
SER N   CA   sing N N 300 
SER N   H    sing N N 301 
SER N   H2   sing N N 302 
SER CA  C    sing N N 303 
SER CA  CB   sing N N 304 
SER CA  HA   sing N N 305 
SER C   O    doub N N 306 
SER C   OXT  sing N N 307 
SER CB  OG   sing N N 308 
SER CB  HB2  sing N N 309 
SER CB  HB3  sing N N 310 
SER OG  HG   sing N N 311 
SER OXT HXT  sing N N 312 
THR N   CA   sing N N 313 
THR N   H    sing N N 314 
THR N   H2   sing N N 315 
THR CA  C    sing N N 316 
THR CA  CB   sing N N 317 
THR CA  HA   sing N N 318 
THR C   O    doub N N 319 
THR C   OXT  sing N N 320 
THR CB  OG1  sing N N 321 
THR CB  CG2  sing N N 322 
THR CB  HB   sing N N 323 
THR OG1 HG1  sing N N 324 
THR CG2 HG21 sing N N 325 
THR CG2 HG22 sing N N 326 
THR CG2 HG23 sing N N 327 
THR OXT HXT  sing N N 328 
TRP N   CA   sing N N 329 
TRP N   H    sing N N 330 
TRP N   H2   sing N N 331 
TRP CA  C    sing N N 332 
TRP CA  CB   sing N N 333 
TRP CA  HA   sing N N 334 
TRP C   O    doub N N 335 
TRP C   OXT  sing N N 336 
TRP CB  CG   sing N N 337 
TRP CB  HB2  sing N N 338 
TRP CB  HB3  sing N N 339 
TRP CG  CD1  doub Y N 340 
TRP CG  CD2  sing Y N 341 
TRP CD1 NE1  sing Y N 342 
TRP CD1 HD1  sing N N 343 
TRP CD2 CE2  doub Y N 344 
TRP CD2 CE3  sing Y N 345 
TRP NE1 CE2  sing Y N 346 
TRP NE1 HE1  sing N N 347 
TRP CE2 CZ2  sing Y N 348 
TRP CE3 CZ3  doub Y N 349 
TRP CE3 HE3  sing N N 350 
TRP CZ2 CH2  doub Y N 351 
TRP CZ2 HZ2  sing N N 352 
TRP CZ3 CH2  sing Y N 353 
TRP CZ3 HZ3  sing N N 354 
TRP CH2 HH2  sing N N 355 
TRP OXT HXT  sing N N 356 
TYR N   CA   sing N N 357 
TYR N   H    sing N N 358 
TYR N   H2   sing N N 359 
TYR CA  C    sing N N 360 
TYR CA  CB   sing N N 361 
TYR CA  HA   sing N N 362 
TYR C   O    doub N N 363 
TYR C   OXT  sing N N 364 
TYR CB  CG   sing N N 365 
TYR CB  HB2  sing N N 366 
TYR CB  HB3  sing N N 367 
TYR CG  CD1  doub Y N 368 
TYR CG  CD2  sing Y N 369 
TYR CD1 CE1  sing Y N 370 
TYR CD1 HD1  sing N N 371 
TYR CD2 CE2  doub Y N 372 
TYR CD2 HD2  sing N N 373 
TYR CE1 CZ   doub Y N 374 
TYR CE1 HE1  sing N N 375 
TYR CE2 CZ   sing Y N 376 
TYR CE2 HE2  sing N N 377 
TYR CZ  OH   sing N N 378 
TYR OH  HH   sing N N 379 
TYR OXT HXT  sing N N 380 
VAL N   CA   sing N N 381 
VAL N   H    sing N N 382 
VAL N   H2   sing N N 383 
VAL CA  C    sing N N 384 
VAL CA  CB   sing N N 385 
VAL CA  HA   sing N N 386 
VAL C   O    doub N N 387 
VAL C   OXT  sing N N 388 
VAL CB  CG1  sing N N 389 
VAL CB  CG2  sing N N 390 
VAL CB  HB   sing N N 391 
VAL CG1 HG11 sing N N 392 
VAL CG1 HG12 sing N N 393 
VAL CG1 HG13 sing N N 394 
VAL CG2 HG21 sing N N 395 
VAL CG2 HG22 sing N N 396 
VAL CG2 HG23 sing N N 397 
VAL OXT HXT  sing N N 398 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-10 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JHX 
_em_admin.last_update        2025-02-05 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              'Versatile Aromatic Prenyltransferase auraA mutant-Y207A in complex with DMSPP' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          60172 
_em_entity_assembly_naturalsource.organism             'Penicillium solitum' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Other government' China 
'Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City (Grant No: 2021CXLH0012)' 1 
'Other government' China 'Major Basic Research Programs of Natural Science Foundation of Shandong Province (ZR2019ZD18)' 2 
'Other government' China 'Qingdao Marine Science and Technology Center (No.2022QNLM030003-1)' 3 
# 
_atom_sites.entry_id                    9JHX 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . SER A 1 23  ? 137.240 104.453 125.616 1.00 57.39 ? 23  SER A N   1 
ATOM   2     C CA  . SER A 1 23  ? 137.228 105.265 124.407 1.00 57.39 ? 23  SER A CA  1 
ATOM   3     C C   . SER A 1 23  ? 136.463 104.559 123.303 1.00 57.39 ? 23  SER A C   1 
ATOM   4     O O   . SER A 1 23  ? 136.903 103.529 122.800 1.00 57.39 ? 23  SER A O   1 
ATOM   5     C CB  . SER A 1 23  ? 138.651 105.568 123.944 1.00 57.39 ? 23  SER A CB  1 
ATOM   6     O OG  . SER A 1 23  ? 139.291 104.394 123.477 1.00 57.39 ? 23  SER A OG  1 
ATOM   7     N N   . PRO A 1 24  ? 135.316 105.107 122.923 1.00 50.76 ? 24  PRO A N   1 
ATOM   8     C CA  . PRO A 1 24  ? 134.518 104.473 121.877 1.00 50.76 ? 24  PRO A CA  1 
ATOM   9     C C   . PRO A 1 24  ? 135.174 104.638 120.520 1.00 50.76 ? 24  PRO A C   1 
ATOM   10    O O   . PRO A 1 24  ? 136.214 105.281 120.369 1.00 50.76 ? 24  PRO A O   1 
ATOM   11    C CB  . PRO A 1 24  ? 133.185 105.221 121.945 1.00 50.76 ? 24  PRO A CB  1 
ATOM   12    C CG  . PRO A 1 24  ? 133.549 106.558 122.460 1.00 50.76 ? 24  PRO A CG  1 
ATOM   13    C CD  . PRO A 1 24  ? 134.706 106.357 123.400 1.00 50.76 ? 24  PRO A CD  1 
ATOM   14    N N   . SER A 1 25  ? 134.557 104.033 119.536 1.00 45.68 ? 25  SER A N   1 
ATOM   15    C CA  . SER A 1 25  ? 134.937 104.223 118.151 1.00 45.68 ? 25  SER A CA  1 
ATOM   16    C C   . SER A 1 25  ? 133.938 105.143 117.476 1.00 45.68 ? 25  SER A C   1 
ATOM   17    O O   . SER A 1 25  ? 132.792 105.256 117.917 1.00 45.68 ? 25  SER A O   1 
ATOM   18    C CB  . SER A 1 25  ? 134.980 102.884 117.432 1.00 45.68 ? 25  SER A CB  1 
ATOM   19    O OG  . SER A 1 25  ? 133.742 102.219 117.566 1.00 45.68 ? 25  SER A OG  1 
ATOM   20    N N   . PRO A 1 26  ? 134.346 105.824 116.413 1.00 42.82 ? 26  PRO A N   1 
ATOM   21    C CA  . PRO A 1 26  ? 133.443 106.763 115.745 1.00 42.82 ? 26  PRO A CA  1 
ATOM   22    C C   . PRO A 1 26  ? 132.068 106.202 115.461 1.00 42.82 ? 26  PRO A C   1 
ATOM   23    O O   . PRO A 1 26  ? 131.081 106.899 115.673 1.00 42.82 ? 26  PRO A O   1 
ATOM   24    C CB  . PRO A 1 26  ? 134.191 107.088 114.456 1.00 42.82 ? 26  PRO A CB  1 
ATOM   25    C CG  . PRO A 1 26  ? 135.595 107.006 114.849 1.00 42.82 ? 26  PRO A CG  1 
ATOM   26    C CD  . PRO A 1 26  ? 135.697 105.880 115.837 1.00 42.82 ? 26  PRO A CD  1 
ATOM   27    N N   . TRP A 1 27  ? 131.959 104.956 115.015 1.00 42.25 ? 27  TRP A N   1 
ATOM   28    C CA  . TRP A 1 27  ? 130.624 104.441 114.744 1.00 42.25 ? 27  TRP A CA  1 
ATOM   29    C C   . TRP A 1 27  ? 129.864 104.182 116.035 1.00 42.25 ? 27  TRP A C   1 
ATOM   30    O O   . TRP A 1 27  ? 128.664 104.446 116.109 1.00 42.25 ? 27  TRP A O   1 
ATOM   31    C CB  . TRP A 1 27  ? 130.682 103.189 113.868 1.00 42.25 ? 27  TRP A CB  1 
ATOM   32    C CG  . TRP A 1 27  ? 131.621 102.144 114.287 1.00 42.25 ? 27  TRP A CG  1 
ATOM   33    C CD1 . TRP A 1 27  ? 131.322 101.002 114.948 1.00 42.25 ? 27  TRP A CD1 1 
ATOM   34    C CD2 . TRP A 1 27  ? 133.017 102.108 114.036 1.00 42.25 ? 27  TRP A CD2 1 
ATOM   35    N NE1 . TRP A 1 27  ? 132.451 100.262 115.148 1.00 42.25 ? 27  TRP A NE1 1 
ATOM   36    C CE2 . TRP A 1 27  ? 133.508 100.922 114.591 1.00 42.25 ? 27  TRP A CE2 1 
ATOM   37    C CE3 . TRP A 1 27  ? 133.905 102.972 113.400 1.00 42.25 ? 27  TRP A CE3 1 
ATOM   38    C CZ2 . TRP A 1 27  ? 134.842 100.576 114.534 1.00 42.25 ? 27  TRP A CZ2 1 
ATOM   39    C CZ3 . TRP A 1 27  ? 135.229 102.630 113.347 1.00 42.25 ? 27  TRP A CZ3 1 
ATOM   40    C CH2 . TRP A 1 27  ? 135.687 101.443 113.910 1.00 42.25 ? 27  TRP A CH2 1 
ATOM   41    N N   . ASP A 1 28  ? 130.547 103.708 117.075 1.00 46.45 ? 28  ASP A N   1 
ATOM   42    C CA  . ASP A 1 28  ? 129.885 103.492 118.355 1.00 46.45 ? 28  ASP A CA  1 
ATOM   43    C C   . ASP A 1 28  ? 129.374 104.803 118.931 1.00 46.45 ? 28  ASP A C   1 
ATOM   44    O O   . ASP A 1 28  ? 128.180 104.957 119.216 1.00 46.45 ? 28  ASP A O   1 
ATOM   45    C CB  . ASP A 1 28  ? 130.853 102.833 119.327 1.00 46.45 ? 28  ASP A CB  1 
ATOM   46    C CG  . ASP A 1 28  ? 131.256 101.459 118.890 1.00 46.45 ? 28  ASP A CG  1 
ATOM   47    O OD1 . ASP A 1 28  ? 130.367 100.686 118.485 1.00 46.45 ? 28  ASP A OD1 1 
ATOM   48    O OD2 . ASP A 1 28  ? 132.463 101.149 118.948 1.00 46.45 ? 28  ASP A OD2 1 
ATOM   49    N N   . PHE A 1 29  ? 130.285 105.757 119.121 1.00 43.72 ? 29  PHE A N   1 
ATOM   50    C CA  . PHE A 1 29  ? 129.913 107.068 119.632 1.00 43.72 ? 29  PHE A CA  1 
ATOM   51    C C   . PHE A 1 29  ? 128.815 107.696 118.792 1.00 43.72 ? 29  PHE A C   1 
ATOM   52    O O   . PHE A 1 29  ? 127.844 108.239 119.327 1.00 43.72 ? 29  PHE A O   1 
ATOM   53    C CB  . PHE A 1 29  ? 131.146 107.965 119.660 1.00 43.72 ? 29  PHE A CB  1 
ATOM   54    C CG  . PHE A 1 29  ? 130.974 109.214 120.463 1.00 43.72 ? 29  PHE A CG  1 
ATOM   55    C CD1 . PHE A 1 29  ? 130.215 109.215 121.615 1.00 43.72 ? 29  PHE A CD1 1 
ATOM   56    C CD2 . PHE A 1 29  ? 131.586 110.387 120.075 1.00 43.72 ? 29  PHE A CD2 1 
ATOM   57    C CE1 . PHE A 1 29  ? 130.064 110.361 122.354 1.00 43.72 ? 29  PHE A CE1 1 
ATOM   58    C CE2 . PHE A 1 29  ? 131.435 111.534 120.811 1.00 43.72 ? 29  PHE A CE2 1 
ATOM   59    C CZ  . PHE A 1 29  ? 130.674 111.520 121.950 1.00 43.72 ? 29  PHE A CZ  1 
ATOM   60    N N   . LEU A 1 30  ? 128.943 107.614 117.473 1.00 39.88 ? 30  LEU A N   1 
ATOM   61    C CA  . LEU A 1 30  ? 127.988 108.274 116.601 1.00 39.88 ? 30  LEU A CA  1 
ATOM   62    C C   . LEU A 1 30  ? 126.624 107.616 116.680 1.00 39.88 ? 30  LEU A C   1 
ATOM   63    O O   . LEU A 1 30  ? 125.607 108.306 116.744 1.00 39.88 ? 30  LEU A O   1 
ATOM   64    C CB  . LEU A 1 30  ? 128.522 108.284 115.177 1.00 39.88 ? 30  LEU A CB  1 
ATOM   65    C CG  . LEU A 1 30  ? 129.567 109.373 114.944 1.00 39.88 ? 30  LEU A CG  1 
ATOM   66    C CD1 . LEU A 1 30  ? 130.200 109.240 113.574 1.00 39.88 ? 30  LEU A CD1 1 
ATOM   67    C CD2 . LEU A 1 30  ? 128.946 110.734 115.122 1.00 39.88 ? 30  LEU A CD2 1 
ATOM   68    N N   . GLY A 1 31  ? 126.571 106.288 116.694 1.00 42.91 ? 31  GLY A N   1 
ATOM   69    C CA  . GLY A 1 31  ? 125.303 105.624 116.918 1.00 42.91 ? 31  GLY A CA  1 
ATOM   70    C C   . GLY A 1 31  ? 124.711 105.980 118.259 1.00 42.91 ? 31  GLY A C   1 
ATOM   71    O O   . GLY A 1 31  ? 123.491 105.953 118.434 1.00 42.91 ? 31  GLY A O   1 
ATOM   72    N N   . ARG A 1 32  ? 125.564 106.335 119.220 1.00 44.17 ? 32  ARG A N   1 
ATOM   73    C CA  . ARG A 1 32  ? 125.061 106.774 120.514 1.00 44.17 ? 32  ARG A CA  1 
ATOM   74    C C   . ARG A 1 32  ? 124.450 108.168 120.436 1.00 44.17 ? 32  ARG A C   1 
ATOM   75    O O   . ARG A 1 32  ? 123.379 108.410 121.001 1.00 44.17 ? 32  ARG A O   1 
ATOM   76    C CB  . ARG A 1 32  ? 126.181 106.732 121.545 1.00 44.17 ? 32  ARG A CB  1 
ATOM   77    C CG  . ARG A 1 32  ? 126.619 105.334 121.886 1.00 44.17 ? 32  ARG A CG  1 
ATOM   78    C CD  . ARG A 1 32  ? 126.935 105.215 123.339 1.00 44.17 ? 32  ARG A CD  1 
ATOM   79    N NE  . ARG A 1 32  ? 128.247 105.762 123.627 1.00 44.17 ? 32  ARG A NE  1 
ATOM   80    C CZ  . ARG A 1 32  ? 129.348 105.030 123.687 1.00 44.17 ? 32  ARG A CZ  1 
ATOM   81    N NH1 . ARG A 1 32  ? 129.280 103.726 123.476 1.00 44.17 ? 32  ARG A NH1 1 
ATOM   82    N NH2 . ARG A 1 32  ? 130.513 105.599 123.956 1.00 44.17 ? 32  ARG A NH2 1 
ATOM   83    N N   . VAL A 1 33  ? 125.101 109.095 119.735 1.00 40.48 ? 33  VAL A N   1 
ATOM   84    C CA  . VAL A 1 33  ? 124.690 110.494 119.805 1.00 40.48 ? 33  VAL A CA  1 
ATOM   85    C C   . VAL A 1 33  ? 123.786 110.901 118.647 1.00 40.48 ? 33  VAL A C   1 
ATOM   86    O O   . VAL A 1 33  ? 122.941 111.787 118.805 1.00 40.48 ? 33  VAL A O   1 
ATOM   87    C CB  . VAL A 1 33  ? 125.908 111.432 119.889 1.00 40.48 ? 33  VAL A CB  1 
ATOM   88    C CG1 . VAL A 1 33  ? 126.848 110.980 120.968 1.00 40.48 ? 33  VAL A CG1 1 
ATOM   89    C CG2 . VAL A 1 33  ? 126.618 111.509 118.578 1.00 40.48 ? 33  VAL A CG2 1 
ATOM   90    N N   . LEU A 1 34  ? 123.929 110.266 117.488 1.00 37.30 ? 34  LEU A N   1 
ATOM   91    C CA  . LEU A 1 34  ? 123.232 110.753 116.306 1.00 37.30 ? 34  LEU A CA  1 
ATOM   92    C C   . LEU A 1 34  ? 121.741 110.474 116.393 1.00 37.30 ? 34  LEU A C   1 
ATOM   93    O O   . LEU A 1 34  ? 121.305 109.454 116.924 1.00 37.30 ? 34  LEU A O   1 
ATOM   94    C CB  . LEU A 1 34  ? 123.787 110.113 115.037 1.00 37.30 ? 34  LEU A CB  1 
ATOM   95    C CG  . LEU A 1 34  ? 125.168 110.549 114.559 1.00 37.30 ? 34  LEU A CG  1 
ATOM   96    C CD1 . LEU A 1 34  ? 125.601 109.723 113.375 1.00 37.30 ? 34  LEU A CD1 1 
ATOM   97    C CD2 . LEU A 1 34  ? 125.171 112.010 114.220 1.00 37.30 ? 34  LEU A CD2 1 
ATOM   98    N N   . GLN A 1 35  ? 120.960 111.404 115.863 1.00 40.48 ? 35  GLN A N   1 
ATOM   99    C CA  . GLN A 1 35  ? 119.537 111.208 115.662 1.00 40.48 ? 35  GLN A CA  1 
ATOM   100   C C   . GLN A 1 35  ? 119.327 110.730 114.238 1.00 40.48 ? 35  GLN A C   1 
ATOM   101   O O   . GLN A 1 35  ? 119.868 111.319 113.300 1.00 40.48 ? 35  GLN A O   1 
ATOM   102   C CB  . GLN A 1 35  ? 118.756 112.498 115.902 1.00 40.48 ? 35  GLN A CB  1 
ATOM   103   C CG  . GLN A 1 35  ? 119.172 113.268 117.130 1.00 40.48 ? 35  GLN A CG  1 
ATOM   104   C CD  . GLN A 1 35  ? 118.683 112.626 118.395 1.00 40.48 ? 35  GLN A CD  1 
ATOM   105   O OE1 . GLN A 1 35  ? 119.458 112.368 119.313 1.00 40.48 ? 35  GLN A OE1 1 
ATOM   106   N NE2 . GLN A 1 35  ? 117.389 112.357 118.455 1.00 40.48 ? 35  GLN A NE2 1 
ATOM   107   N N   . PHE A 1 36  ? 118.554 109.668 114.079 1.00 37.30 ? 36  PHE A N   1 
ATOM   108   C CA  . PHE A 1 36  ? 118.308 109.068 112.780 1.00 37.30 ? 36  PHE A CA  1 
ATOM   109   C C   . PHE A 1 36  ? 116.905 109.410 112.317 1.00 37.30 ? 36  PHE A C   1 
ATOM   110   O O   . PHE A 1 36  ? 115.950 109.312 113.089 1.00 37.30 ? 36  PHE A O   1 
ATOM   111   C CB  . PHE A 1 36  ? 118.488 107.557 112.844 1.00 37.30 ? 36  PHE A CB  1 
ATOM   112   C CG  . PHE A 1 36  ? 119.902 107.136 113.047 1.00 37.30 ? 36  PHE A CG  1 
ATOM   113   C CD1 . PHE A 1 36  ? 120.412 106.979 114.309 1.00 37.30 ? 36  PHE A CD1 1 
ATOM   114   C CD2 . PHE A 1 36  ? 120.726 106.908 111.971 1.00 37.30 ? 36  PHE A CD2 1 
ATOM   115   C CE1 . PHE A 1 36  ? 121.711 106.598 114.491 1.00 37.30 ? 36  PHE A CE1 1 
ATOM   116   C CE2 . PHE A 1 36  ? 122.021 106.526 112.151 1.00 37.30 ? 36  PHE A CE2 1 
ATOM   117   C CZ  . PHE A 1 36  ? 122.514 106.369 113.412 1.00 37.30 ? 36  PHE A CZ  1 
ATOM   118   N N   . GLN A 1 37  ? 116.784 109.817 111.054 1.00 41.15 ? 37  GLN A N   1 
ATOM   119   C CA  . GLN A 1 37  ? 115.473 110.181 110.533 1.00 41.15 ? 37  GLN A CA  1 
ATOM   120   C C   . GLN A 1 37  ? 114.537 108.986 110.488 1.00 41.15 ? 37  GLN A C   1 
ATOM   121   O O   . GLN A 1 37  ? 113.321 109.144 110.624 1.00 41.15 ? 37  GLN A O   1 
ATOM   122   C CB  . GLN A 1 37  ? 115.596 110.771 109.136 1.00 41.15 ? 37  GLN A CB  1 
ATOM   123   C CG  . GLN A 1 37  ? 116.679 111.785 108.961 1.00 41.15 ? 37  GLN A CG  1 
ATOM   124   C CD  . GLN A 1 37  ? 116.649 112.385 107.576 1.00 41.15 ? 37  GLN A CD  1 
ATOM   125   O OE1 . GLN A 1 37  ? 115.585 112.528 106.979 1.00 41.15 ? 37  GLN A OE1 1 
ATOM   126   N NE2 . GLN A 1 37  ? 117.818 112.712 107.042 1.00 41.15 ? 37  GLN A NE2 1 
ATOM   127   N N   . HIS A 1 38  ? 115.078 107.790 110.290 1.00 36.13 ? 38  HIS A N   1 
ATOM   128   C CA  . HIS A 1 38  ? 114.270 106.602 110.103 1.00 36.13 ? 38  HIS A CA  1 
ATOM   129   C C   . HIS A 1 38  ? 114.943 105.427 110.790 1.00 36.13 ? 38  HIS A C   1 
ATOM   130   O O   . HIS A 1 38  ? 116.170 105.371 110.894 1.00 36.13 ? 38  HIS A O   1 
ATOM   131   C CB  . HIS A 1 38  ? 114.068 106.315 108.620 1.00 36.13 ? 38  HIS A CB  1 
ATOM   132   C CG  . HIS A 1 38  ? 112.990 105.323 108.335 1.00 36.13 ? 38  HIS A CG  1 
ATOM   133   N ND1 . HIS A 1 38  ? 113.159 103.970 108.519 1.00 36.13 ? 38  HIS A ND1 1 
ATOM   134   C CD2 . HIS A 1 38  ? 111.734 105.485 107.864 1.00 36.13 ? 38  HIS A CD2 1 
ATOM   135   C CE1 . HIS A 1 38  ? 112.050 103.340 108.182 1.00 36.13 ? 38  HIS A CE1 1 
ATOM   136   N NE2 . HIS A 1 38  ? 111.169 104.236 107.780 1.00 36.13 ? 38  HIS A NE2 1 
ATOM   137   N N   . GLY A 1 39  ? 114.122 104.490 111.265 1.00 38.00 ? 39  GLY A N   1 
ATOM   138   C CA  . GLY A 1 39  ? 114.661 103.327 111.947 1.00 38.00 ? 39  GLY A CA  1 
ATOM   139   C C   . GLY A 1 39  ? 115.508 102.459 111.041 1.00 38.00 ? 39  GLY A C   1 
ATOM   140   O O   . GLY A 1 39  ? 116.528 101.913 111.466 1.00 38.00 ? 39  GLY A O   1 
ATOM   141   N N   . ASP A 1 40  ? 115.093 102.312 109.782 1.00 37.80 ? 40  ASP A N   1 
ATOM   142   C CA  . ASP A 1 40  ? 115.879 101.536 108.832 1.00 37.80 ? 40  ASP A CA  1 
ATOM   143   C C   . ASP A 1 40  ? 117.259 102.127 108.644 1.00 37.80 ? 40  ASP A C   1 
ATOM   144   O O   . ASP A 1 40  ? 118.223 101.386 108.452 1.00 37.80 ? 40  ASP A O   1 
ATOM   145   C CB  . ASP A 1 40  ? 115.162 101.449 107.489 1.00 37.80 ? 40  ASP A CB  1 
ATOM   146   C CG  . ASP A 1 40  ? 114.274 100.230 107.383 1.00 37.80 ? 40  ASP A CG  1 
ATOM   147   O OD1 . ASP A 1 40  ? 114.169 99.490  108.377 1.00 37.80 ? 40  ASP A OD1 1 
ATOM   148   O OD2 . ASP A 1 40  ? 113.674 100.012 106.311 1.00 37.80 ? 40  ASP A OD2 1 
ATOM   149   N N   . HIS A 1 41  ? 117.383 103.452 108.696 1.00 35.00 ? 41  HIS A N   1 
ATOM   150   C CA  . HIS A 1 41  ? 118.712 104.043 108.665 1.00 35.00 ? 41  HIS A CA  1 
ATOM   151   C C   . HIS A 1 41  ? 119.514 103.620 109.883 1.00 35.00 ? 41  HIS A C   1 
ATOM   152   O O   . HIS A 1 41  ? 120.718 103.393 109.785 1.00 35.00 ? 41  HIS A O   1 
ATOM   153   C CB  . HIS A 1 41  ? 118.637 105.567 108.591 1.00 35.00 ? 41  HIS A CB  1 
ATOM   154   C CG  . HIS A 1 41  ? 117.699 106.094 107.549 1.00 35.00 ? 41  HIS A CG  1 
ATOM   155   N ND1 . HIS A 1 41  ? 117.410 107.434 107.430 1.00 35.00 ? 41  HIS A ND1 1 
ATOM   156   C CD2 . HIS A 1 41  ? 116.987 105.471 106.584 1.00 35.00 ? 41  HIS A CD2 1 
ATOM   157   C CE1 . HIS A 1 41  ? 116.555 107.613 106.442 1.00 35.00 ? 41  HIS A CE1 1 
ATOM   158   N NE2 . HIS A 1 41  ? 116.281 106.437 105.913 1.00 35.00 ? 41  HIS A NE2 1 
ATOM   159   N N   . LYS A 1 42  ? 118.858 103.462 111.030 1.00 38.28 ? 42  LYS A N   1 
ATOM   160   C CA  . LYS A 1 42  ? 119.563 103.016 112.225 1.00 38.28 ? 42  LYS A CA  1 
ATOM   161   C C   . LYS A 1 42  ? 120.041 101.577 112.085 1.00 38.28 ? 42  LYS A C   1 
ATOM   162   O O   . LYS A 1 42  ? 121.172 101.250 112.456 1.00 38.28 ? 42  LYS A O   1 
ATOM   163   C CB  . LYS A 1 42  ? 118.654 103.168 113.438 1.00 38.28 ? 42  LYS A CB  1 
ATOM   164   C CG  . LYS A 1 42  ? 119.241 102.647 114.719 1.00 38.28 ? 42  LYS A CG  1 
ATOM   165   C CD  . LYS A 1 42  ? 120.531 103.344 115.055 1.00 38.28 ? 42  LYS A CD  1 
ATOM   166   C CE  . LYS A 1 42  ? 120.924 103.085 116.488 1.00 38.28 ? 42  LYS A CE  1 
ATOM   167   N NZ  . LYS A 1 42  ? 122.356 102.725 116.599 1.00 38.28 ? 42  LYS A NZ  1 
ATOM   168   N N   . ARG A 1 43  ? 119.196 100.706 111.542 1.00 39.33 ? 43  ARG A N   1 
ATOM   169   C CA  . ARG A 1 43  ? 119.583 99.311  111.382 1.00 39.33 ? 43  ARG A CA  1 
ATOM   170   C C   . ARG A 1 43  ? 120.675 99.158  110.333 1.00 39.33 ? 43  ARG A C   1 
ATOM   171   O O   . ARG A 1 43  ? 121.643 98.412  110.536 1.00 39.33 ? 43  ARG A O   1 
ATOM   172   C CB  . ARG A 1 43  ? 118.355 98.490  111.032 1.00 39.33 ? 43  ARG A CB  1 
ATOM   173   C CG  . ARG A 1 43  ? 117.157 98.903  111.845 1.00 39.33 ? 43  ARG A CG  1 
ATOM   174   C CD  . ARG A 1 43  ? 115.919 98.130  111.479 1.00 39.33 ? 43  ARG A CD  1 
ATOM   175   N NE  . ARG A 1 43  ? 116.168 96.696  111.489 1.00 39.33 ? 43  ARG A NE  1 
ATOM   176   C CZ  . ARG A 1 43  ? 116.261 95.959  112.591 1.00 39.33 ? 43  ARG A CZ  1 
ATOM   177   N NH1 . ARG A 1 43  ? 116.491 94.657  112.498 1.00 39.33 ? 43  ARG A NH1 1 
ATOM   178   N NH2 . ARG A 1 43  ? 116.119 96.516  113.785 1.00 39.33 ? 43  ARG A NH2 1 
ATOM   179   N N   . TRP A 1 44  ? 120.545 99.862  109.210 1.00 35.53 ? 44  TRP A N   1 
ATOM   180   C CA  . TRP A 1 44  ? 121.628 99.902  108.242 1.00 35.53 ? 44  TRP A CA  1 
ATOM   181   C C   . TRP A 1 44  ? 122.892 100.456 108.861 1.00 35.53 ? 44  TRP A C   1 
ATOM   182   O O   . TRP A 1 44  ? 123.987 100.039 108.494 1.00 35.53 ? 44  TRP A O   1 
ATOM   183   C CB  . TRP A 1 44  ? 121.240 100.750 107.036 1.00 35.53 ? 44  TRP A CB  1 
ATOM   184   C CG  . TRP A 1 44  ? 120.345 100.095 106.046 1.00 35.53 ? 44  TRP A CG  1 
ATOM   185   C CD1 . TRP A 1 44  ? 119.135 100.535 105.640 1.00 35.53 ? 44  TRP A CD1 1 
ATOM   186   C CD2 . TRP A 1 44  ? 120.602 98.899  105.313 1.00 35.53 ? 44  TRP A CD2 1 
ATOM   187   N NE1 . TRP A 1 44  ? 118.608 99.688  104.709 1.00 35.53 ? 44  TRP A NE1 1 
ATOM   188   C CE2 . TRP A 1 44  ? 119.494 98.671  104.492 1.00 35.53 ? 44  TRP A CE2 1 
ATOM   189   C CE3 . TRP A 1 44  ? 121.662 97.995  105.276 1.00 35.53 ? 44  TRP A CE3 1 
ATOM   190   C CZ2 . TRP A 1 44  ? 119.410 97.582  103.649 1.00 35.53 ? 44  TRP A CZ2 1 
ATOM   191   C CZ3 . TRP A 1 44  ? 121.577 96.919  104.439 1.00 35.53 ? 44  TRP A CZ3 1 
ATOM   192   C CH2 . TRP A 1 44  ? 120.461 96.718  103.638 1.00 35.53 ? 44  TRP A CH2 1 
ATOM   193   N N   . TRP A 1 45  ? 122.772 101.412 109.780 1.00 36.08 ? 45  TRP A N   1 
ATOM   194   C CA  . TRP A 1 45  ? 123.954 101.907 110.470 1.00 36.08 ? 45  TRP A CA  1 
ATOM   195   C C   . TRP A 1 45  ? 124.610 100.787 111.248 1.00 36.08 ? 45  TRP A C   1 
ATOM   196   O O   . TRP A 1 45  ? 125.799 100.510 111.077 1.00 36.08 ? 45  TRP A O   1 
ATOM   197   C CB  . TRP A 1 45  ? 123.584 103.061 111.403 1.00 36.08 ? 45  TRP A CB  1 
ATOM   198   C CG  . TRP A 1 45  ? 124.762 103.603 112.171 1.00 36.08 ? 45  TRP A CG  1 
ATOM   199   C CD1 . TRP A 1 45  ? 125.145 103.261 113.430 1.00 36.08 ? 45  TRP A CD1 1 
ATOM   200   C CD2 . TRP A 1 45  ? 125.709 104.574 111.717 1.00 36.08 ? 45  TRP A CD2 1 
ATOM   201   N NE1 . TRP A 1 45  ? 126.267 103.954 113.788 1.00 36.08 ? 45  TRP A NE1 1 
ATOM   202   C CE2 . TRP A 1 45  ? 126.633 104.769 112.751 1.00 36.08 ? 45  TRP A CE2 1 
ATOM   203   C CE3 . TRP A 1 45  ? 125.865 105.296 110.534 1.00 36.08 ? 45  TRP A CE3 1 
ATOM   204   C CZ2 . TRP A 1 45  ? 127.695 105.653 112.640 1.00 36.08 ? 45  TRP A CZ2 1 
ATOM   205   C CZ3 . TRP A 1 45  ? 126.918 106.172 110.429 1.00 36.08 ? 45  TRP A CZ3 1 
ATOM   206   C CH2 . TRP A 1 45  ? 127.819 106.343 111.472 1.00 36.08 ? 45  TRP A CH2 1 
ATOM   207   N N   . ASP A 1 46  ? 123.824 100.108 112.079 1.00 37.10 ? 46  ASP A N   1 
ATOM   208   C CA  . ASP A 1 46  ? 124.342 99.019  112.895 1.00 37.10 ? 46  ASP A CA  1 
ATOM   209   C C   . ASP A 1 46  ? 125.061 97.981  112.055 1.00 37.10 ? 46  ASP A C   1 
ATOM   210   O O   . ASP A 1 46  ? 126.075 97.424  112.481 1.00 37.10 ? 46  ASP A O   1 
ATOM   211   C CB  . ASP A 1 46  ? 123.201 98.374  113.668 1.00 37.10 ? 46  ASP A CB  1 
ATOM   212   C CG  . ASP A 1 46  ? 122.624 99.291  114.701 1.00 37.10 ? 46  ASP A CG  1 
ATOM   213   O OD1 . ASP A 1 46  ? 123.355 100.182 115.172 1.00 37.10 ? 46  ASP A OD1 1 
ATOM   214   O OD2 . ASP A 1 46  ? 121.442 99.124  115.050 1.00 37.10 ? 46  ASP A OD2 1 
ATOM   215   N N   . VAL A 1 47  ? 124.553 97.708  110.858 1.00 37.15 ? 47  VAL A N   1 
ATOM   216   C CA  . VAL A 1 47  ? 125.180 96.701  110.003 1.00 37.15 ? 47  VAL A CA  1 
ATOM   217   C C   . VAL A 1 47  ? 126.415 97.263  109.309 1.00 37.15 ? 47  VAL A C   1 
ATOM   218   O O   . VAL A 1 47  ? 127.530 96.767  109.486 1.00 37.15 ? 47  VAL A O   1 
ATOM   219   C CB  . VAL A 1 47  ? 124.169 96.159  108.981 1.00 37.15 ? 47  VAL A CB  1 
ATOM   220   C CG1 . VAL A 1 47  ? 124.794 95.049  108.170 1.00 37.15 ? 47  VAL A CG1 1 
ATOM   221   C CG2 . VAL A 1 47  ? 122.947 95.663  109.689 1.00 37.15 ? 47  VAL A CG2 1 
ATOM   222   N N   . LEU A 1 48  ? 126.233 98.302  108.501 1.00 37.21 ? 48  LEU A N   1 
ATOM   223   C CA  . LEU A 1 48  ? 127.287 98.782  107.621 1.00 37.21 ? 48  LEU A CA  1 
ATOM   224   C C   . LEU A 1 48  ? 128.368 99.524  108.380 1.00 37.21 ? 48  LEU A C   1 
ATOM   225   O O   . LEU A 1 48  ? 129.555 99.252  108.194 1.00 37.21 ? 48  LEU A O   1 
ATOM   226   C CB  . LEU A 1 48  ? 126.695 99.695  106.553 1.00 37.21 ? 48  LEU A CB  1 
ATOM   227   C CG  . LEU A 1 48  ? 125.577 99.131  105.688 1.00 37.21 ? 48  LEU A CG  1 
ATOM   228   C CD1 . LEU A 1 48  ? 125.112 100.178 104.724 1.00 37.21 ? 48  LEU A CD1 1 
ATOM   229   C CD2 . LEU A 1 48  ? 126.070 97.925  104.948 1.00 37.21 ? 48  LEU A CD2 1 
ATOM   230   N N   . ALA A 1 49  ? 127.976 100.491 109.206 1.00 38.58 ? 49  ALA A N   1 
ATOM   231   C CA  . ALA A 1 49  ? 128.938 101.384 109.843 1.00 38.58 ? 49  ALA A CA  1 
ATOM   232   C C   . ALA A 1 49  ? 130.099 100.663 110.502 1.00 38.58 ? 49  ALA A C   1 
ATOM   233   O O   . ALA A 1 49  ? 131.224 101.175 110.416 1.00 38.58 ? 49  ALA A O   1 
ATOM   234   C CB  . ALA A 1 49  ? 128.209 102.272 110.856 1.00 38.58 ? 49  ALA A CB  1 
ATOM   235   N N   . PRO A 1 50  ? 129.927 99.515  111.157 1.00 38.72 ? 50  PRO A N   1 
ATOM   236   C CA  . PRO A 1 50  ? 131.112 98.772  111.591 1.00 38.72 ? 50  PRO A CA  1 
ATOM   237   C C   . PRO A 1 50  ? 132.007 98.369  110.440 1.00 38.72 ? 50  PRO A C   1 
ATOM   238   O O   . PRO A 1 50  ? 133.212 98.605  110.495 1.00 38.72 ? 50  PRO A O   1 
ATOM   239   C CB  . PRO A 1 50  ? 130.512 97.566  112.307 1.00 38.72 ? 50  PRO A CB  1 
ATOM   240   C CG  . PRO A 1 50  ? 129.230 98.048  112.796 1.00 38.72 ? 50  PRO A CG  1 
ATOM   241   C CD  . PRO A 1 50  ? 128.705 98.950  111.745 1.00 38.72 ? 50  PRO A CD  1 
ATOM   242   N N   . VAL A 1 51  ? 131.450 97.777  109.385 1.00 41.84 ? 51  VAL A N   1 
ATOM   243   C CA  . VAL A 1 51  ? 132.271 97.322  108.264 1.00 41.84 ? 51  VAL A CA  1 
ATOM   244   C C   . VAL A 1 51  ? 132.974 98.500  107.602 1.00 41.84 ? 51  VAL A C   1 
ATOM   245   O O   . VAL A 1 51  ? 134.182 98.469  107.344 1.00 41.84 ? 51  VAL A O   1 
ATOM   246   C CB  . VAL A 1 51  ? 131.404 96.549  107.255 1.00 41.84 ? 51  VAL A CB  1 
ATOM   247   C CG1 . VAL A 1 51  ? 132.193 96.258  105.997 1.00 41.84 ? 51  VAL A CG1 1 
ATOM   248   C CG2 . VAL A 1 51  ? 130.874 95.273  107.875 1.00 41.84 ? 51  VAL A CG2 1 
ATOM   249   N N   . PHE A 1 52  ? 132.218 99.554  107.312 1.00 43.12 ? 52  PHE A N   1 
ATOM   250   C CA  . PHE A 1 52  ? 132.789 100.739 106.692 1.00 43.12 ? 52  PHE A CA  1 
ATOM   251   C C   . PHE A 1 52  ? 133.866 101.351 107.573 1.00 43.12 ? 52  PHE A C   1 
ATOM   252   O O   . PHE A 1 52  ? 134.977 101.632 107.114 1.00 43.12 ? 52  PHE A O   1 
ATOM   253   C CB  . PHE A 1 52  ? 131.681 101.747 106.414 1.00 43.12 ? 52  PHE A CB  1 
ATOM   254   C CG  . PHE A 1 52  ? 130.875 101.432 105.196 1.00 43.12 ? 52  PHE A CG  1 
ATOM   255   C CD1 . PHE A 1 52  ? 130.946 100.187 104.606 1.00 43.12 ? 52  PHE A CD1 1 
ATOM   256   C CD2 . PHE A 1 52  ? 130.050 102.378 104.633 1.00 43.12 ? 52  PHE A CD2 1 
ATOM   257   C CE1 . PHE A 1 52  ? 130.208 99.896  103.485 1.00 43.12 ? 52  PHE A CE1 1 
ATOM   258   C CE2 . PHE A 1 52  ? 129.311 102.085 103.511 1.00 43.12 ? 52  PHE A CE2 1 
ATOM   259   C CZ  . PHE A 1 52  ? 129.390 100.843 102.941 1.00 43.12 ? 52  PHE A CZ  1 
ATOM   260   N N   . GLY A 1 53  ? 133.552 101.558 108.852 1.00 43.63 ? 53  GLY A N   1 
ATOM   261   C CA  . GLY A 1 53  ? 134.506 102.150 109.765 1.00 43.63 ? 53  GLY A CA  1 
ATOM   262   C C   . GLY A 1 53  ? 135.744 101.308 109.968 1.00 43.63 ? 53  GLY A C   1 
ATOM   263   O O   . GLY A 1 53  ? 136.827 101.845 110.182 1.00 43.63 ? 53  GLY A O   1 
ATOM   264   N N   . ILE A 1 54  ? 135.614 99.986  109.879 1.00 45.82 ? 54  ILE A N   1 
ATOM   265   C CA  . ILE A 1 54  ? 136.778 99.136  110.081 1.00 45.82 ? 54  ILE A CA  1 
ATOM   266   C C   . ILE A 1 54  ? 137.626 99.077  108.823 1.00 45.82 ? 54  ILE A C   1 
ATOM   267   O O   . ILE A 1 54  ? 138.851 98.959  108.899 1.00 45.82 ? 54  ILE A O   1 
ATOM   268   C CB  . ILE A 1 54  ? 136.340 97.740  110.545 1.00 45.82 ? 54  ILE A CB  1 
ATOM   269   C CG1 . ILE A 1 54  ? 135.868 97.798  111.997 1.00 45.82 ? 54  ILE A CG1 1 
ATOM   270   C CG2 . ILE A 1 54  ? 137.473 96.747  110.414 1.00 45.82 ? 54  ILE A CG2 1 
ATOM   271   C CD1 . ILE A 1 54  ? 134.866 96.731  112.363 1.00 45.82 ? 54  ILE A CD1 1 
ATOM   272   N N   . SER A 1 55  ? 137.009 99.185  107.651 1.00 48.27 ? 55  SER A N   1 
ATOM   273   C CA  . SER A 1 55  ? 137.799 99.342  106.438 1.00 48.27 ? 55  SER A CA  1 
ATOM   274   C C   . SER A 1 55  ? 138.544 100.668 106.451 1.00 48.27 ? 55  SER A C   1 
ATOM   275   O O   . SER A 1 55  ? 139.699 100.752 106.019 1.00 48.27 ? 55  SER A O   1 
ATOM   276   C CB  . SER A 1 55  ? 136.891 99.245  105.220 1.00 48.27 ? 55  SER A CB  1 
ATOM   277   O OG  . SER A 1 55  ? 136.253 97.984  105.169 1.00 48.27 ? 55  SER A OG  1 
ATOM   278   N N   . MET A 1 56  ? 137.887 101.716 106.943 1.00 48.60 ? 56  MET A N   1 
ATOM   279   C CA  . MET A 1 56  ? 138.528 103.018 107.041 1.00 48.60 ? 56  MET A CA  1 
ATOM   280   C C   . MET A 1 56  ? 139.667 103.008 108.053 1.00 48.60 ? 56  MET A C   1 
ATOM   281   O O   . MET A 1 56  ? 140.766 103.491 107.762 1.00 48.60 ? 56  MET A O   1 
ATOM   282   C CB  . MET A 1 56  ? 137.485 104.067 107.406 1.00 48.60 ? 56  MET A CB  1 
ATOM   283   C CG  . MET A 1 56  ? 136.372 104.208 106.394 1.00 48.60 ? 56  MET A CG  1 
ATOM   284   S SD  . MET A 1 56  ? 135.256 105.560 106.808 1.00 48.60 ? 56  MET A SD  1 
ATOM   285   C CE  . MET A 1 56  ? 134.010 105.387 105.549 1.00 48.60 ? 56  MET A CE  1 
ATOM   286   N N   . ALA A 1 57  ? 139.434 102.454 109.238 1.00 50.00 ? 57  ALA A N   1 
ATOM   287   C CA  . ALA A 1 57  ? 140.398 102.467 110.323 1.00 50.00 ? 57  ALA A CA  1 
ATOM   288   C C   . ALA A 1 57  ? 141.364 101.304 110.267 1.00 50.00 ? 57  ALA A C   1 
ATOM   289   O O   . ALA A 1 57  ? 142.194 101.163 111.167 1.00 50.00 ? 57  ALA A O   1 
ATOM   290   C CB  . ALA A 1 57  ? 139.671 102.452 111.665 1.00 50.00 ? 57  ALA A CB  1 
ATOM   291   N N   . SER A 1 58  ? 141.263 100.457 109.255 1.00 53.70 ? 58  SER A N   1 
ATOM   292   C CA  . SER A 1 58  ? 142.183 99.350  109.081 1.00 53.70 ? 58  SER A CA  1 
ATOM   293   C C   . SER A 1 58  ? 143.164 99.600  107.949 1.00 53.70 ? 58  SER A C   1 
ATOM   294   O O   . SER A 1 58  ? 143.955 98.716  107.615 1.00 53.70 ? 58  SER A O   1 
ATOM   295   C CB  . SER A 1 58  ? 141.396 98.067  108.855 1.00 53.70 ? 58  SER A CB  1 
ATOM   296   O OG  . SER A 1 58  ? 140.527 98.227  107.758 1.00 53.70 ? 58  SER A OG  1 
ATOM   297   N N   . ILE A 1 59  ? 143.113 100.785 107.347 1.00 52.98 ? 59  ILE A N   1 
ATOM   298   C CA  . ILE A 1 59  ? 144.154 101.265 106.446 1.00 52.98 ? 59  ILE A CA  1 
ATOM   299   C C   . ILE A 1 59  ? 144.708 102.612 106.881 1.00 52.98 ? 59  ILE A C   1 
ATOM   300   O O   . ILE A 1 59  ? 145.755 103.026 106.383 1.00 52.98 ? 59  ILE A O   1 
ATOM   301   C CB  . ILE A 1 59  ? 143.635 101.340 105.000 1.00 52.98 ? 59  ILE A CB  1 
ATOM   302   C CG1 . ILE A 1 59  ? 142.427 102.263 104.926 1.00 52.98 ? 59  ILE A CG1 1 
ATOM   303   C CG2 . ILE A 1 59  ? 143.262 99.967  104.496 1.00 52.98 ? 59  ILE A CG2 1 
ATOM   304   C CD1 . ILE A 1 59  ? 141.916 102.459 103.543 1.00 52.98 ? 59  ILE A CD1 1 
ATOM   305   N N   . GLY A 1 60  ? 144.032 103.309 107.788 1.00 53.22 ? 60  GLY A N   1 
ATOM   306   C CA  . GLY A 1 60  ? 144.543 104.516 108.389 1.00 53.22 ? 60  GLY A CA  1 
ATOM   307   C C   . GLY A 1 60  ? 143.752 105.780 108.142 1.00 53.22 ? 60  GLY A C   1 
ATOM   308   O O   . GLY A 1 60  ? 144.308 106.869 108.322 1.00 53.22 ? 60  GLY A O   1 
ATOM   309   N N   . TYR A 1 61  ? 142.488 105.688 107.736 1.00 46.79 ? 61  TYR A N   1 
ATOM   310   C CA  . TYR A 1 61  ? 141.692 106.899 107.573 1.00 46.79 ? 61  TYR A CA  1 
ATOM   311   C C   . TYR A 1 61  ? 141.656 107.675 108.881 1.00 46.79 ? 61  TYR A C   1 
ATOM   312   O O   . TYR A 1 61  ? 141.145 107.182 109.889 1.00 46.79 ? 61  TYR A O   1 
ATOM   313   C CB  . TYR A 1 61  ? 140.273 106.557 107.124 1.00 46.79 ? 61  TYR A CB  1 
ATOM   314   C CG  . TYR A 1 61  ? 140.114 106.354 105.634 1.00 46.79 ? 61  TYR A CG  1 
ATOM   315   C CD1 . TYR A 1 61  ? 141.177 105.936 104.854 1.00 46.79 ? 61  TYR A CD1 1 
ATOM   316   C CD2 . TYR A 1 61  ? 138.890 106.562 105.009 1.00 46.79 ? 61  TYR A CD2 1 
ATOM   317   C CE1 . TYR A 1 61  ? 141.033 105.746 103.502 1.00 46.79 ? 61  TYR A CE1 1 
ATOM   318   C CE2 . TYR A 1 61  ? 138.737 106.365 103.658 1.00 46.79 ? 61  TYR A CE2 1 
ATOM   319   C CZ  . TYR A 1 61  ? 139.815 105.957 102.911 1.00 46.79 ? 61  TYR A CZ  1 
ATOM   320   O OH  . TYR A 1 61  ? 139.684 105.759 101.560 1.00 46.79 ? 61  TYR A OH  1 
ATOM   321   N N   . LYS A 1 62  ? 142.217 108.885 108.865 1.00 46.60 ? 62  LYS A N   1 
ATOM   322   C CA  . LYS A 1 62  ? 142.315 109.698 110.071 1.00 46.60 ? 62  LYS A CA  1 
ATOM   323   C C   . LYS A 1 62  ? 140.955 109.864 110.733 1.00 46.60 ? 62  LYS A C   1 
ATOM   324   O O   . LYS A 1 62  ? 139.930 109.994 110.064 1.00 46.60 ? 62  LYS A O   1 
ATOM   325   C CB  . LYS A 1 62  ? 142.908 111.063 109.736 1.00 46.60 ? 62  LYS A CB  1 
ATOM   326   C CG  . LYS A 1 62  ? 144.290 110.989 109.121 1.00 46.60 ? 62  LYS A CG  1 
ATOM   327   C CD  . LYS A 1 62  ? 144.807 112.368 108.748 1.00 46.60 ? 62  LYS A CD  1 
ATOM   328   C CE  . LYS A 1 62  ? 146.200 112.295 108.142 1.00 46.60 ? 62  LYS A CE  1 
ATOM   329   N NZ  . LYS A 1 62  ? 146.242 111.500 106.883 1.00 46.60 ? 62  LYS A NZ  1 
ATOM   330   N N   . LEU A 1 63  ? 140.959 109.877 112.063 1.00 46.50 ? 63  LEU A N   1 
ATOM   331   C CA  . LEU A 1 63  ? 139.724 109.709 112.816 1.00 46.50 ? 63  LEU A CA  1 
ATOM   332   C C   . LEU A 1 63  ? 138.685 110.768 112.476 1.00 46.50 ? 63  LEU A C   1 
ATOM   333   O O   . LEU A 1 63  ? 137.487 110.468 112.449 1.00 46.50 ? 63  LEU A O   1 
ATOM   334   C CB  . LEU A 1 63  ? 140.025 109.726 114.308 1.00 46.50 ? 63  LEU A CB  1 
ATOM   335   C CG  . LEU A 1 63  ? 139.012 108.968 115.154 1.00 46.50 ? 63  LEU A CG  1 
ATOM   336   C CD1 . LEU A 1 63  ? 139.123 107.514 114.818 1.00 46.50 ? 63  LEU A CD1 1 
ATOM   337   C CD2 . LEU A 1 63  ? 139.277 109.174 116.619 1.00 46.50 ? 63  LEU A CD2 1 
ATOM   338   N N   . ASP A 1 64  ? 139.111 112.007 112.218 1.00 47.20 ? 64  ASP A N   1 
ATOM   339   C CA  . ASP A 1 64  ? 138.146 113.033 111.834 1.00 47.20 ? 64  ASP A CA  1 
ATOM   340   C C   . ASP A 1 64  ? 137.655 112.809 110.414 1.00 47.20 ? 64  ASP A C   1 
ATOM   341   O O   . ASP A 1 64  ? 136.509 113.134 110.086 1.00 47.20 ? 64  ASP A O   1 
ATOM   342   C CB  . ASP A 1 64  ? 138.759 114.418 111.956 1.00 47.20 ? 64  ASP A CB  1 
ATOM   343   C CG  . ASP A 1 64  ? 139.832 114.660 110.933 1.00 47.20 ? 64  ASP A CG  1 
ATOM   344   O OD1 . ASP A 1 64  ? 140.916 114.062 111.060 1.00 47.20 ? 64  ASP A OD1 1 
ATOM   345   O OD2 . ASP A 1 64  ? 139.585 115.432 109.986 1.00 47.20 ? 64  ASP A OD2 1 
ATOM   346   N N   . VAL A 1 65  ? 138.506 112.241 109.558 1.00 44.45 ? 65  VAL A N   1 
ATOM   347   C CA  . VAL A 1 65  ? 138.062 111.846 108.229 1.00 44.45 ? 65  VAL A CA  1 
ATOM   348   C C   . VAL A 1 65  ? 137.084 110.689 108.333 1.00 44.45 ? 65  VAL A C   1 
ATOM   349   O O   . VAL A 1 65  ? 136.115 110.603 107.571 1.00 44.45 ? 65  VAL A O   1 
ATOM   350   C CB  . VAL A 1 65  ? 139.273 111.501 107.346 1.00 44.45 ? 65  VAL A CB  1 
ATOM   351   C CG1 . VAL A 1 65  ? 138.829 110.912 106.038 1.00 44.45 ? 65  VAL A CG1 1 
ATOM   352   C CG2 . VAL A 1 65  ? 140.117 112.733 107.105 1.00 44.45 ? 65  VAL A CG2 1 
ATOM   353   N N   . GLN A 1 66  ? 137.316 109.783 109.280 1.00 41.74 ? 66  GLN A N   1 
ATOM   354   C CA  . GLN A 1 66  ? 136.331 108.751 109.561 1.00 41.74 ? 66  GLN A CA  1 
ATOM   355   C C   . GLN A 1 66  ? 135.007 109.376 109.954 1.00 41.74 ? 66  GLN A C   1 
ATOM   356   O O   . GLN A 1 66  ? 133.950 108.981 109.461 1.00 41.74 ? 66  GLN A O   1 
ATOM   357   C CB  . GLN A 1 66  ? 136.824 107.835 110.674 1.00 41.74 ? 66  GLN A CB  1 
ATOM   358   C CG  . GLN A 1 66  ? 137.970 106.948 110.312 1.00 41.74 ? 66  GLN A CG  1 
ATOM   359   C CD  . GLN A 1 66  ? 138.339 106.038 111.451 1.00 41.74 ? 66  GLN A CD  1 
ATOM   360   O OE1 . GLN A 1 66  ? 137.505 105.695 112.273 1.00 41.74 ? 66  GLN A OE1 1 
ATOM   361   N NE2 . GLN A 1 66  ? 139.593 105.653 111.514 1.00 41.74 ? 66  GLN A NE2 1 
ATOM   362   N N   . TYR A 1 67  ? 135.045 110.345 110.866 1.00 42.44 ? 67  TYR A N   1 
ATOM   363   C CA  . TYR A 1 67  ? 133.821 111.045 111.234 1.00 42.44 ? 67  TYR A CA  1 
ATOM   364   C C   . TYR A 1 67  ? 133.145 111.653 110.017 1.00 42.44 ? 67  TYR A C   1 
ATOM   365   O O   . TYR A 1 67  ? 131.928 111.536 109.855 1.00 42.44 ? 67  TYR A O   1 
ATOM   366   C CB  . TYR A 1 67  ? 134.121 112.124 112.266 1.00 42.44 ? 67  TYR A CB  1 
ATOM   367   C CG  . TYR A 1 67  ? 133.970 111.662 113.690 1.00 42.44 ? 67  TYR A CG  1 
ATOM   368   C CD1 . TYR A 1 67  ? 132.740 111.724 114.326 1.00 42.44 ? 67  TYR A CD1 1 
ATOM   369   C CD2 . TYR A 1 67  ? 135.052 111.174 114.401 1.00 42.44 ? 67  TYR A CD2 1 
ATOM   370   C CE1 . TYR A 1 67  ? 132.594 111.308 115.626 1.00 42.44 ? 67  TYR A CE1 1 
ATOM   371   C CE2 . TYR A 1 67  ? 134.915 110.756 115.700 1.00 42.44 ? 67  TYR A CE2 1 
ATOM   372   C CZ  . TYR A 1 67  ? 133.686 110.826 116.309 1.00 42.44 ? 67  TYR A CZ  1 
ATOM   373   O OH  . TYR A 1 67  ? 133.547 110.404 117.606 1.00 42.44 ? 67  TYR A OH  1 
ATOM   374   N N   . ARG A 1 68  ? 133.922 112.294 109.143 1.00 43.55 ? 68  ARG A N   1 
ATOM   375   C CA  . ARG A 1 68  ? 133.345 112.959 107.979 1.00 43.55 ? 68  ARG A CA  1 
ATOM   376   C C   . ARG A 1 68  ? 132.673 111.963 107.049 1.00 43.55 ? 68  ARG A C   1 
ATOM   377   O O   . ARG A 1 68  ? 131.518 112.148 106.654 1.00 43.55 ? 68  ARG A O   1 
ATOM   378   C CB  . ARG A 1 68  ? 134.422 113.737 107.233 1.00 43.55 ? 68  ARG A CB  1 
ATOM   379   C CG  . ARG A 1 68  ? 134.915 114.942 107.987 1.00 43.55 ? 68  ARG A CG  1 
ATOM   380   C CD  . ARG A 1 68  ? 135.741 115.841 107.106 1.00 43.55 ? 68  ARG A CD  1 
ATOM   381   N NE  . ARG A 1 68  ? 134.947 116.380 106.015 1.00 43.55 ? 68  ARG A NE  1 
ATOM   382   C CZ  . ARG A 1 68  ? 135.399 117.264 105.139 1.00 43.55 ? 68  ARG A CZ  1 
ATOM   383   N NH1 . ARG A 1 68  ? 136.643 117.707 105.230 1.00 43.55 ? 68  ARG A NH1 1 
ATOM   384   N NH2 . ARG A 1 68  ? 134.608 117.703 104.172 1.00 43.55 ? 68  ARG A NH2 1 
ATOM   385   N N   . HIS A 1 69  ? 133.386 110.903 106.676 1.00 39.91 ? 69  HIS A N   1 
ATOM   386   C CA  . HIS A 1 69  ? 132.812 109.931 105.755 1.00 39.91 ? 69  HIS A CA  1 
ATOM   387   C C   . HIS A 1 69  ? 131.635 109.208 106.383 1.00 39.91 ? 69  HIS A C   1 
ATOM   388   O O   . HIS A 1 69  ? 130.657 108.908 105.701 1.00 39.91 ? 69  HIS A O   1 
ATOM   389   C CB  . HIS A 1 69  ? 133.870 108.932 105.305 1.00 39.91 ? 69  HIS A CB  1 
ATOM   390   C CG  . HIS A 1 69  ? 134.782 109.453 104.238 1.00 39.91 ? 69  HIS A CG  1 
ATOM   391   N ND1 . HIS A 1 69  ? 134.345 110.258 103.212 1.00 39.91 ? 69  HIS A ND1 1 
ATOM   392   C CD2 . HIS A 1 69  ? 136.107 109.276 104.037 1.00 39.91 ? 69  HIS A CD2 1 
ATOM   393   C CE1 . HIS A 1 69  ? 135.362 110.555 102.427 1.00 39.91 ? 69  HIS A CE1 1 
ATOM   394   N NE2 . HIS A 1 69  ? 136.443 109.973 102.905 1.00 39.91 ? 69  HIS A NE2 1 
ATOM   395   N N   . LEU A 1 70  ? 131.705 108.924 107.681 1.00 38.81 ? 70  LEU A N   1 
ATOM   396   C CA  . LEU A 1 70  ? 130.597 108.263 108.347 1.00 38.81 ? 70  LEU A CA  1 
ATOM   397   C C   . LEU A 1 70  ? 129.396 109.179 108.453 1.00 38.81 ? 70  LEU A C   1 
ATOM   398   O O   . LEU A 1 70  ? 128.260 108.711 108.416 1.00 38.81 ? 70  LEU A O   1 
ATOM   399   C CB  . LEU A 1 70  ? 131.038 107.784 109.723 1.00 38.81 ? 70  LEU A CB  1 
ATOM   400   C CG  . LEU A 1 70  ? 131.968 106.576 109.660 1.00 38.81 ? 70  LEU A CG  1 
ATOM   401   C CD1 . LEU A 1 70  ? 132.716 106.377 110.958 1.00 38.81 ? 70  LEU A CD1 1 
ATOM   402   C CD2 . LEU A 1 70  ? 131.177 105.348 109.310 1.00 38.81 ? 70  LEU A CD2 1 
ATOM   403   N N   . LEU A 1 71  ? 129.619 110.485 108.536 1.00 37.35 ? 71  LEU A N   1 
ATOM   404   C CA  . LEU A 1 71  ? 128.503 111.416 108.532 1.00 37.35 ? 71  LEU A CA  1 
ATOM   405   C C   . LEU A 1 71  ? 127.938 111.605 107.137 1.00 37.35 ? 71  LEU A C   1 
ATOM   406   O O   . LEU A 1 71  ? 126.758 111.923 106.991 1.00 37.35 ? 71  LEU A O   1 
ATOM   407   C CB  . LEU A 1 71  ? 128.945 112.748 109.122 1.00 37.35 ? 71  LEU A CB  1 
ATOM   408   C CG  . LEU A 1 71  ? 129.166 112.694 110.629 1.00 37.35 ? 71  LEU A CG  1 
ATOM   409   C CD1 . LEU A 1 71  ? 129.931 113.903 111.072 1.00 37.35 ? 71  LEU A CD1 1 
ATOM   410   C CD2 . LEU A 1 71  ? 127.849 112.605 111.357 1.00 37.35 ? 71  LEU A CD2 1 
ATOM   411   N N   . VAL A 1 72  ? 128.762 111.409 106.111 1.00 37.24 ? 72  VAL A N   1 
ATOM   412   C CA  . VAL A 1 72  ? 128.261 111.396 104.739 1.00 37.24 ? 72  VAL A CA  1 
ATOM   413   C C   . VAL A 1 72  ? 127.411 110.156 104.507 1.00 37.24 ? 72  VAL A C   1 
ATOM   414   O O   . VAL A 1 72  ? 126.299 110.228 103.976 1.00 37.24 ? 72  VAL A O   1 
ATOM   415   C CB  . VAL A 1 72  ? 129.430 111.472 103.742 1.00 37.24 ? 72  VAL A CB  1 
ATOM   416   C CG1 . VAL A 1 72  ? 129.008 110.945 102.405 1.00 37.24 ? 72  VAL A CG1 1 
ATOM   417   C CG2 . VAL A 1 72  ? 129.930 112.891 103.604 1.00 37.24 ? 72  VAL A CG2 1 
ATOM   418   N N   . LEU A 1 73  ? 127.932 109.000 104.902 1.00 34.05 ? 73  LEU A N   1 
ATOM   419   C CA  . LEU A 1 73  ? 127.175 107.756 104.867 1.00 34.05 ? 73  LEU A CA  1 
ATOM   420   C C   . LEU A 1 73  ? 125.889 107.865 105.670 1.00 34.05 ? 73  LEU A C   1 
ATOM   421   O O   . LEU A 1 73  ? 124.859 107.313 105.283 1.00 34.05 ? 73  LEU A O   1 
ATOM   422   C CB  . LEU A 1 73  ? 128.061 106.628 105.393 1.00 34.05 ? 73  LEU A CB  1 
ATOM   423   C CG  . LEU A 1 73  ? 127.487 105.376 106.042 1.00 34.05 ? 73  LEU A CG  1 
ATOM   424   C CD1 . LEU A 1 73  ? 126.951 104.427 105.011 1.00 34.05 ? 73  LEU A CD1 1 
ATOM   425   C CD2 . LEU A 1 73  ? 128.555 104.699 106.859 1.00 34.05 ? 73  LEU A CD2 1 
ATOM   426   N N   . TYR A 1 74  ? 125.933 108.574 106.791 1.00 35.22 ? 74  TYR A N   1 
ATOM   427   C CA  . TYR A 1 74  ? 124.746 108.798 107.601 1.00 35.22 ? 74  TYR A CA  1 
ATOM   428   C C   . TYR A 1 74  ? 123.790 109.776 106.940 1.00 35.22 ? 74  TYR A C   1 
ATOM   429   O O   . TYR A 1 74  ? 122.575 109.686 107.138 1.00 35.22 ? 74  TYR A O   1 
ATOM   430   C CB  . TYR A 1 74  ? 125.179 109.303 108.975 1.00 35.22 ? 74  TYR A CB  1 
ATOM   431   C CG  . TYR A 1 74  ? 124.206 110.221 109.674 1.00 35.22 ? 74  TYR A CG  1 
ATOM   432   C CD1 . TYR A 1 74  ? 123.081 109.722 110.299 1.00 35.22 ? 74  TYR A CD1 1 
ATOM   433   C CD2 . TYR A 1 74  ? 124.435 111.582 109.743 1.00 35.22 ? 74  TYR A CD2 1 
ATOM   434   C CE1 . TYR A 1 74  ? 122.205 110.547 110.950 1.00 35.22 ? 74  TYR A CE1 1 
ATOM   435   C CE2 . TYR A 1 74  ? 123.560 112.413 110.391 1.00 35.22 ? 74  TYR A CE2 1 
ATOM   436   C CZ  . TYR A 1 74  ? 122.446 111.887 110.991 1.00 35.22 ? 74  TYR A CZ  1 
ATOM   437   O OH  . TYR A 1 74  ? 121.565 112.703 111.644 1.00 35.22 ? 74  TYR A OH  1 
ATOM   438   N N   . ASP A 1 75  ? 124.316 110.695 106.139 1.00 39.24 ? 75  ASP A N   1 
ATOM   439   C CA  . ASP A 1 75  ? 123.551 111.797 105.580 1.00 39.24 ? 75  ASP A CA  1 
ATOM   440   C C   . ASP A 1 75  ? 123.147 111.583 104.132 1.00 39.24 ? 75  ASP A C   1 
ATOM   441   O O   . ASP A 1 75  ? 122.023 111.918 103.755 1.00 39.24 ? 75  ASP A O   1 
ATOM   442   C CB  . ASP A 1 75  ? 124.362 113.083 105.682 1.00 39.24 ? 75  ASP A CB  1 
ATOM   443   C CG  . ASP A 1 75  ? 123.571 114.295 105.279 1.00 39.24 ? 75  ASP A CG  1 
ATOM   444   O OD1 . ASP A 1 75  ? 122.438 114.455 105.775 1.00 39.24 ? 75  ASP A OD1 1 
ATOM   445   O OD2 . ASP A 1 75  ? 124.081 115.089 104.463 1.00 39.24 ? 75  ASP A OD2 1 
ATOM   446   N N   . ALA A 1 76  ? 124.032 111.034 103.309 1.00 36.27 ? 76  ALA A N   1 
ATOM   447   C CA  . ALA A 1 76  ? 123.803 110.977 101.875 1.00 36.27 ? 76  ALA A CA  1 
ATOM   448   C C   . ALA A 1 76  ? 123.366 109.605 101.380 1.00 36.27 ? 76  ALA A C   1 
ATOM   449   O O   . ALA A 1 76  ? 122.382 109.507 100.647 1.00 36.27 ? 76  ALA A O   1 
ATOM   450   C CB  . ALA A 1 76  ? 125.065 111.422 101.131 1.00 36.27 ? 76  ALA A CB  1 
ATOM   451   N N   . VAL A 1 77  ? 124.063 108.538 101.756 1.00 34.20 ? 77  VAL A N   1 
ATOM   452   C CA  . VAL A 1 77  ? 123.886 107.258 101.092 1.00 34.20 ? 77  VAL A CA  1 
ATOM   453   C C   . VAL A 1 77  ? 122.889 106.365 101.819 1.00 34.20 ? 77  VAL A C   1 
ATOM   454   O O   . VAL A 1 77  ? 122.131 105.642 101.177 1.00 34.20 ? 77  VAL A O   1 
ATOM   455   C CB  . VAL A 1 77  ? 125.244 106.551 100.899 1.00 34.20 ? 77  VAL A CB  1 
ATOM   456   C CG1 . VAL A 1 77  ? 126.303 107.549 100.502 1.00 34.20 ? 77  VAL A CG1 1 
ATOM   457   C CG2 . VAL A 1 77  ? 125.648 105.798 102.109 1.00 34.20 ? 77  VAL A CG2 1 
ATOM   458   N N   . ILE A 1 78  ? 122.850 106.393 103.146 1.00 32.08 ? 78  ILE A N   1 
ATOM   459   C CA  . ILE A 1 78  ? 121.957 105.496 103.875 1.00 32.08 ? 78  ILE A CA  1 
ATOM   460   C C   . ILE A 1 78  ? 120.509 105.923 103.676 1.00 32.08 ? 78  ILE A C   1 
ATOM   461   O O   . ILE A 1 78  ? 119.648 105.055 103.492 1.00 32.08 ? 78  ILE A O   1 
ATOM   462   C CB  . ILE A 1 78  ? 122.310 105.414 105.366 1.00 32.08 ? 78  ILE A CB  1 
ATOM   463   C CG1 . ILE A 1 78  ? 123.411 104.391 105.602 1.00 32.08 ? 78  ILE A CG1 1 
ATOM   464   C CG2 . ILE A 1 78  ? 121.124 104.982 106.150 1.00 32.08 ? 78  ILE A CG2 1 
ATOM   465   C CD1 . ILE A 1 78  ? 123.820 104.272 107.030 1.00 32.08 ? 78  ILE A CD1 1 
ATOM   466   N N   . PRO A 1 79  ? 120.171 107.213 103.692 1.00 31.82 ? 79  PRO A N   1 
ATOM   467   C CA  . PRO A 1 79  ? 118.791 107.586 103.361 1.00 31.82 ? 79  PRO A CA  1 
ATOM   468   C C   . PRO A 1 79  ? 118.416 107.252 101.931 1.00 31.82 ? 79  PRO A C   1 
ATOM   469   O O   . PRO A 1 79  ? 117.240 107.328 101.568 1.00 31.82 ? 79  PRO A O   1 
ATOM   470   C CB  . PRO A 1 79  ? 118.771 109.093 103.609 1.00 31.82 ? 79  PRO A CB  1 
ATOM   471   C CG  . PRO A 1 79  ? 119.836 109.313 104.575 1.00 31.82 ? 79  PRO A CG  1 
ATOM   472   C CD  . PRO A 1 79  ? 120.909 108.365 104.230 1.00 31.82 ? 79  PRO A CD  1 
ATOM   473   N N   . ASN A 1 80  ? 119.396 106.870 101.117 1.00 36.65 ? 80  ASN A N   1 
ATOM   474   C CA  . ASN A 1 80  ? 119.193 106.503 99.722  1.00 36.65 ? 80  ASN A CA  1 
ATOM   475   C C   . ASN A 1 80  ? 119.605 105.060 99.474  1.00 36.65 ? 80  ASN A C   1 
ATOM   476   O O   . ASN A 1 80  ? 120.210 104.747 98.451  1.00 36.65 ? 80  ASN A O   1 
ATOM   477   C CB  . ASN A 1 80  ? 119.967 107.439 98.797  1.00 36.65 ? 80  ASN A CB  1 
ATOM   478   C CG  . ASN A 1 80  ? 119.519 108.873 98.921  1.00 36.65 ? 80  ASN A CG  1 
ATOM   479   O OD1 . ASN A 1 80  ? 118.398 109.214 98.559  1.00 36.65 ? 80  ASN A OD1 1 
ATOM   480   N ND2 . ASN A 1 80  ? 120.395 109.724 99.436  1.00 36.65 ? 80  ASN A ND2 1 
ATOM   481   N N   . MET A 1 81  ? 119.300 104.176 100.417 1.00 35.99 ? 81  MET A N   1 
ATOM   482   C CA  . MET A 1 81  ? 119.653 102.773 100.312 1.00 35.99 ? 81  MET A CA  1 
ATOM   483   C C   . MET A 1 81  ? 118.440 101.866 100.245 1.00 35.99 ? 81  MET A C   1 
ATOM   484   O O   . MET A 1 81  ? 118.571 100.707 99.845  1.00 35.99 ? 81  MET A O   1 
ATOM   485   C CB  . MET A 1 81  ? 120.528 102.364 101.497 1.00 35.99 ? 81  MET A CB  1 
ATOM   486   C CG  . MET A 1 81  ? 121.292 101.093 101.287 1.00 35.99 ? 81  MET A CG  1 
ATOM   487   S SD  . MET A 1 81  ? 122.714 100.989 102.355 1.00 35.99 ? 81  MET A SD  1 
ATOM   488   C CE  . MET A 1 81  ? 123.600 102.439 101.834 1.00 35.99 ? 81  MET A CE  1 
ATOM   489   N N   . GLY A 1 82  ? 117.269 102.364 100.603 1.00 36.98 ? 82  GLY A N   1 
ATOM   490   C CA  . GLY A 1 82  ? 116.078 101.563 100.567 1.00 36.98 ? 82  GLY A CA  1 
ATOM   491   C C   . GLY A 1 82  ? 115.902 100.833 101.872 1.00 36.98 ? 82  GLY A C   1 
ATOM   492   O O   . GLY A 1 82  ? 116.749 100.904 102.762 1.00 36.98 ? 82  GLY A O   1 
ATOM   493   N N   . PRO A 1 83  ? 114.804 100.103 102.007 1.00 40.51 ? 83  PRO A N   1 
ATOM   494   C CA  . PRO A 1 83  ? 114.475 99.513  103.303 1.00 40.51 ? 83  PRO A CA  1 
ATOM   495   C C   . PRO A 1 83  ? 115.452 98.420  103.692 1.00 40.51 ? 83  PRO A C   1 
ATOM   496   O O   . PRO A 1 83  ? 116.227 97.927  102.872 1.00 40.51 ? 83  PRO A O   1 
ATOM   497   C CB  . PRO A 1 83  ? 113.067 98.960  103.089 1.00 40.51 ? 83  PRO A CB  1 
ATOM   498   C CG  . PRO A 1 83  ? 112.984 98.725  101.644 1.00 40.51 ? 83  PRO A CG  1 
ATOM   499   C CD  . PRO A 1 83  ? 113.805 99.778  100.984 1.00 40.51 ? 83  PRO A CD  1 
ATOM   500   N N   . PHE A 1 84  ? 115.420 98.060  104.974 1.00 40.02 ? 84  PHE A N   1 
ATOM   501   C CA  . PHE A 1 84  ? 116.289 97.053  105.573 1.00 40.02 ? 84  PHE A CA  1 
ATOM   502   C C   . PHE A 1 84  ? 115.622 95.685  105.504 1.00 40.02 ? 84  PHE A C   1 
ATOM   503   O O   . PHE A 1 84  ? 114.421 95.575  105.775 1.00 40.02 ? 84  PHE A O   1 
ATOM   504   C CB  . PHE A 1 84  ? 116.604 97.405  107.021 1.00 40.02 ? 84  PHE A CB  1 
ATOM   505   C CG  . PHE A 1 84  ? 117.649 96.538  107.637 1.00 40.02 ? 84  PHE A CG  1 
ATOM   506   C CD1 . PHE A 1 84  ? 118.976 96.731  107.355 1.00 40.02 ? 84  PHE A CD1 1 
ATOM   507   C CD2 . PHE A 1 84  ? 117.303 95.523  108.493 1.00 40.02 ? 84  PHE A CD2 1 
ATOM   508   C CE1 . PHE A 1 84  ? 119.929 95.932  107.913 1.00 40.02 ? 84  PHE A CE1 1 
ATOM   509   C CE2 . PHE A 1 84  ? 118.263 94.722  109.048 1.00 40.02 ? 84  PHE A CE2 1 
ATOM   510   C CZ  . PHE A 1 84  ? 119.574 94.930  108.755 1.00 40.02 ? 84  PHE A CZ  1 
ATOM   511   N N   . PRO A 1 85  ? 116.473 94.660  105.188 1.00 42.02 ? 85  PRO A N   1 
ATOM   512   C CA  . PRO A 1 85  ? 115.866 93.382  105.031 1.00 42.02 ? 85  PRO A CA  1 
ATOM   513   C C   . PRO A 1 85  ? 115.381 92.774  106.304 1.00 42.02 ? 85  PRO A C   1 
ATOM   514   O O   . PRO A 1 85  ? 116.136 92.502  107.208 1.00 42.02 ? 85  PRO A O   1 
ATOM   515   C CB  . PRO A 1 85  ? 116.996 92.571  104.434 1.00 42.02 ? 85  PRO A CB  1 
ATOM   516   C CG  . PRO A 1 85  ? 118.231 93.210  104.875 1.00 42.02 ? 85  PRO A CG  1 
ATOM   517   C CD  . PRO A 1 85  ? 117.861 94.610  104.674 1.00 42.02 ? 85  PRO A CD  1 
ATOM   518   N N   . ASN A 1 86  ? 114.102 92.541  106.389 1.00 51.97 ? 86  ASN A N   1 
ATOM   519   C CA  . ASN A 1 86  ? 113.596 91.840  107.523 1.00 51.97 ? 86  ASN A CA  1 
ATOM   520   C C   . ASN A 1 86  ? 113.870 90.357  107.282 1.00 51.97 ? 86  ASN A C   1 
ATOM   521   O O   . ASN A 1 86  ? 114.404 89.999  106.254 1.00 51.97 ? 86  ASN A O   1 
ATOM   522   C CB  . ASN A 1 86  ? 112.137 92.214  107.877 1.00 51.97 ? 86  ASN A CB  1 
ATOM   523   C CG  . ASN A 1 86  ? 111.113 91.769  106.855 1.00 51.97 ? 86  ASN A CG  1 
ATOM   524   O OD1 . ASN A 1 86  ? 111.233 90.733  106.223 1.00 51.97 ? 86  ASN A OD1 1 
ATOM   525   N ND2 . ASN A 1 86  ? 110.054 92.546  106.738 1.00 51.97 ? 86  ASN A ND2 1 
ATOM   526   N N   . SER A 1 87  ? 113.523 89.481  108.205 1.00 56.91 ? 87  SER A N   1 
ATOM   527   C CA  . SER A 1 87  ? 113.874 88.066  108.104 1.00 56.91 ? 87  SER A CA  1 
ATOM   528   C C   . SER A 1 87  ? 113.406 87.255  106.912 1.00 56.91 ? 87  SER A C   1 
ATOM   529   O O   . SER A 1 87  ? 114.157 86.451  106.376 1.00 56.91 ? 87  SER A O   1 
ATOM   530   C CB  . SER A 1 87  ? 113.283 87.408  109.318 1.00 56.91 ? 87  SER A CB  1 
ATOM   531   O OG  . SER A 1 87  ? 111.894 87.668  109.383 1.00 56.91 ? 87  SER A OG  1 
ATOM   532   N N   . ASN A 1 88  ? 112.173 87.431  106.493 1.00 57.06 ? 88  ASN A N   1 
ATOM   533   C CA  . ASN A 1 88  ? 111.733 86.749  105.310 1.00 57.06 ? 88  ASN A CA  1 
ATOM   534   C C   . ASN A 1 88  ? 111.974 87.662  104.147 1.00 57.06 ? 88  ASN A C   1 
ATOM   535   O O   . ASN A 1 88  ? 111.708 87.274  103.017 1.00 57.06 ? 88  ASN A O   1 
ATOM   536   C CB  . ASN A 1 88  ? 110.261 86.411  105.411 1.00 57.06 ? 88  ASN A CB  1 
ATOM   537   C CG  . ASN A 1 88  ? 109.420 87.542  105.950 1.00 57.06 ? 88  ASN A CG  1 
ATOM   538   O OD1 . ASN A 1 88  ? 109.724 88.128  106.983 1.00 57.06 ? 88  ASN A OD1 1 
ATOM   539   N ND2 . ASN A 1 88  ? 108.316 87.815  105.277 1.00 57.06 ? 88  ASN A ND2 1 
ATOM   540   N N   . ALA A 1 89  ? 112.484 88.865  104.394 1.00 54.08 ? 89  ALA A N   1 
ATOM   541   C CA  . ALA A 1 89  ? 112.657 89.891  103.348 1.00 54.08 ? 89  ALA A CA  1 
ATOM   542   C C   . ALA A 1 89  ? 111.382 90.223  102.611 1.00 54.08 ? 89  ALA A C   1 
ATOM   543   O O   . ALA A 1 89  ? 111.388 90.375  101.414 1.00 54.08 ? 89  ALA A O   1 
ATOM   544   C CB  . ALA A 1 89  ? 113.823 89.622  102.422 1.00 54.08 ? 89  ALA A CB  1 
ATOM   545   N N   . SER A 1 90  ? 110.279 90.303  103.326 1.00 54.54 ? 90  SER A N   1 
ATOM   546   C CA  . SER A 1 90  ? 109.035 90.720  102.725 1.00 54.54 ? 90  SER A CA  1 
ATOM   547   C C   . SER A 1 90  ? 109.084 92.139  102.269 1.00 54.54 ? 90  SER A C   1 
ATOM   548   O O   . SER A 1 90  ? 108.493 92.473  101.267 1.00 54.54 ? 90  SER A O   1 
ATOM   549   C CB  . SER A 1 90  ? 107.931 90.610  103.746 1.00 54.54 ? 90  SER A CB  1 
ATOM   550   O OG  . SER A 1 90  ? 108.154 91.467  104.840 1.00 54.54 ? 90  SER A OG  1 
ATOM   551   N N   . ASN A 1 91  ? 109.801 92.993  102.987 1.00 49.89 ? 91  ASN A N   1 
ATOM   552   C CA  . ASN A 1 91  ? 109.871 94.403  102.687 1.00 49.89 ? 91  ASN A CA  1 
ATOM   553   C C   . ASN A 1 91  ? 110.799 94.881  101.604 1.00 49.89 ? 91  ASN A C   1 
ATOM   554   O O   . ASN A 1 91  ? 110.980 96.064  101.455 1.00 49.89 ? 91  ASN A O   1 
ATOM   555   C CB  . ASN A 1 91  ? 110.186 95.134  103.964 1.00 49.89 ? 91  ASN A CB  1 
ATOM   556   C CG  . ASN A 1 91  ? 111.574 94.884  104.470 1.00 49.89 ? 91  ASN A CG  1 
ATOM   557   O OD1 . ASN A 1 91  ? 112.277 93.982  104.029 1.00 49.89 ? 91  ASN A OD1 1 
ATOM   558   N ND2 . ASN A 1 91  ? 111.973 95.691  105.432 1.00 49.89 ? 91  ASN A ND2 1 
ATOM   559   N N   . ILE A 1 92  ? 111.417 94.004  100.848 1.00 46.91 ? 92  ILE A N   1 
ATOM   560   C CA  . ILE A 1 92  ? 112.192 94.471  99.742  1.00 46.91 ? 92  ILE A CA  1 
ATOM   561   C C   . ILE A 1 92  ? 111.250 94.424  98.575  1.00 46.91 ? 92  ILE A C   1 
ATOM   562   O O   . ILE A 1 92  ? 110.939 93.362  98.079  1.00 46.91 ? 92  ILE A O   1 
ATOM   563   C CB  . ILE A 1 92  ? 113.369 93.578  99.518  1.00 46.91 ? 92  ILE A CB  1 
ATOM   564   C CG1 . ILE A 1 92  ? 114.243 93.582  100.771 1.00 46.91 ? 92  ILE A CG1 1 
ATOM   565   C CG2 . ILE A 1 92  ? 114.164 94.014  98.308  1.00 46.91 ? 92  ILE A CG2 1 
ATOM   566   C CD1 . ILE A 1 92  ? 114.750 94.946  101.185 1.00 46.91 ? 92  ILE A CD1 1 
ATOM   567   N N   . THR A 1 93  ? 110.762 95.570  98.132  1.00 43.82 ? 93  THR A N   1 
ATOM   568   C CA  . THR A 1 93  ? 109.811 95.638  97.052  1.00 43.82 ? 93  THR A CA  1 
ATOM   569   C C   . THR A 1 93  ? 110.439 96.011  95.765  1.00 43.82 ? 93  THR A C   1 
ATOM   570   O O   . THR A 1 93  ? 109.760 96.095  94.779  1.00 43.82 ? 93  THR A O   1 
ATOM   571   C CB  . THR A 1 93  ? 108.741 96.640  97.353  1.00 43.82 ? 93  THR A CB  1 
ATOM   572   O OG1 . THR A 1 93  ? 109.315 97.941  97.383  1.00 43.82 ? 93  THR A OG1 1 
ATOM   573   C CG2 . THR A 1 93  ? 108.115 96.345  98.692  1.00 43.82 ? 93  THR A CG2 1 
ATOM   574   N N   . TRP A 1 94  ? 111.731 96.214  95.747  1.00 42.02 ? 94  TRP A N   1 
ATOM   575   C CA  . TRP A 1 94  ? 112.427 96.517  94.546  1.00 42.02 ? 94  TRP A CA  1 
ATOM   576   C C   . TRP A 1 94  ? 113.204 95.306  94.310  1.00 42.02 ? 94  TRP A C   1 
ATOM   577   O O   . TRP A 1 94  ? 114.210 95.116  94.942  1.00 42.02 ? 94  TRP A O   1 
ATOM   578   C CB  . TRP A 1 94  ? 113.307 97.684  94.761  1.00 42.02 ? 94  TRP A CB  1 
ATOM   579   C CG  . TRP A 1 94  ? 114.215 98.082  93.647  1.00 42.02 ? 94  TRP A CG  1 
ATOM   580   C CD1 . TRP A 1 94  ? 115.558 97.943  93.624  1.00 42.02 ? 94  TRP A CD1 1 
ATOM   581   C CD2 . TRP A 1 94  ? 113.859 98.714  92.414  1.00 42.02 ? 94  TRP A CD2 1 
ATOM   582   N NE1 . TRP A 1 94  ? 116.065 98.427  92.454  1.00 42.02 ? 94  TRP A NE1 1 
ATOM   583   C CE2 . TRP A 1 94  ? 115.039 98.905  91.691  1.00 42.02 ? 94  TRP A CE2 1 
ATOM   584   C CE3 . TRP A 1 94  ? 112.658 99.130  91.850  1.00 42.02 ? 94  TRP A CE3 1 
ATOM   585   C CZ2 . TRP A 1 94  ? 115.054 99.493  90.439  1.00 42.02 ? 94  TRP A CZ2 1 
ATOM   586   C CZ3 . TRP A 1 94  ? 112.676 99.703  90.609  1.00 42.02 ? 94  TRP A CZ3 1 
ATOM   587   C CH2 . TRP A 1 94  ? 113.862 99.877  89.917  1.00 42.02 ? 94  TRP A CH2 1 
ATOM   588   N N   . THR A 1 95  ? 112.824 94.509  93.350  1.00 47.90 ? 95  THR A N   1 
ATOM   589   C CA  . THR A 1 95  ? 113.400 93.194  93.119  1.00 47.90 ? 95  THR A CA  1 
ATOM   590   C C   . THR A 1 95  ? 114.805 93.287  92.539  1.00 47.90 ? 95  THR A C   1 
ATOM   591   O O   . THR A 1 95  ? 115.221 94.313  92.008  1.00 47.90 ? 95  THR A O   1 
ATOM   592   C CB  . THR A 1 95  ? 112.518 92.400  92.171  1.00 47.90 ? 95  THR A CB  1 
ATOM   593   O OG1 . THR A 1 95  ? 112.676 92.915  90.846  1.00 47.90 ? 95  THR A OG1 1 
ATOM   594   C CG2 . THR A 1 95  ? 111.070 92.536  92.579  1.00 47.90 ? 95  THR A CG2 1 
ATOM   595   N N   . SER A 1 96  ? 115.531 92.178  92.634  1.00 51.22 ? 96  SER A N   1 
ATOM   596   C CA  . SER A 1 96  ? 116.922 92.115  92.212  1.00 51.22 ? 96  SER A CA  1 
ATOM   597   C C   . SER A 1 96  ? 117.447 90.686  92.272  1.00 51.22 ? 96  SER A C   1 
ATOM   598   O O   . SER A 1 96  ? 116.958 89.875  93.066  1.00 51.22 ? 96  SER A O   1 
ATOM   599   C CB  . SER A 1 96  ? 117.783 93.022  93.092  1.00 51.22 ? 96  SER A CB  1 
ATOM   600   O OG  . SER A 1 96  ? 119.151 92.935  92.747  1.00 51.22 ? 96  SER A OG  1 
ATOM   601   N N   . PRO A 1 97  ? 118.439 90.336  91.451  1.00 52.25 ? 97  PRO A N   1 
ATOM   602   C CA  . PRO A 1 97  ? 119.127 89.053  91.625  1.00 52.25 ? 97  PRO A CA  1 
ATOM   603   C C   . PRO A 1 97  ? 120.164 89.059  92.733  1.00 52.25 ? 97  PRO A C   1 
ATOM   604   O O   . PRO A 1 97  ? 120.737 88.001  93.024  1.00 52.25 ? 97  PRO A O   1 
ATOM   605   C CB  . PRO A 1 97  ? 119.799 88.826  90.261  1.00 52.25 ? 97  PRO A CB  1 
ATOM   606   C CG  . PRO A 1 97  ? 119.262 89.888  89.357  1.00 52.25 ? 97  PRO A CG  1 
ATOM   607   C CD  . PRO A 1 97  ? 118.871 91.018  90.227  1.00 52.25 ? 97  PRO A CD  1 
ATOM   608   N N   . PHE A 1 98  ? 120.440 90.202  93.341  1.00 51.86 ? 98  PHE A N   1 
ATOM   609   C CA  . PHE A 1 98  ? 121.383 90.317  94.437  1.00 51.86 ? 98  PHE A CA  1 
ATOM   610   C C   . PHE A 1 98  ? 120.653 90.581  95.742  1.00 51.86 ? 98  PHE A C   1 
ATOM   611   O O   . PHE A 1 98  ? 119.483 90.970  95.744  1.00 51.86 ? 98  PHE A O   1 
ATOM   612   C CB  . PHE A 1 98  ? 122.379 91.444  94.161  1.00 51.86 ? 98  PHE A CB  1 
ATOM   613   C CG  . PHE A 1 98  ? 122.781 91.547  92.730  1.00 51.86 ? 98  PHE A CG  1 
ATOM   614   C CD1 . PHE A 1 98  ? 123.405 90.494  92.099  1.00 51.86 ? 98  PHE A CD1 1 
ATOM   615   C CD2 . PHE A 1 98  ? 122.535 92.697  92.013  1.00 51.86 ? 98  PHE A CD2 1 
ATOM   616   C CE1 . PHE A 1 98  ? 123.775 90.589  90.781  1.00 51.86 ? 98  PHE A CE1 1 
ATOM   617   C CE2 . PHE A 1 98  ? 122.903 92.797  90.694  1.00 51.86 ? 98  PHE A CE2 1 
ATOM   618   C CZ  . PHE A 1 98  ? 123.523 91.743  90.078  1.00 51.86 ? 98  PHE A CZ  1 
ATOM   619   N N   . PRO A 1 99  ? 121.304 90.361  96.880  1.00 49.73 ? 99  PRO A N   1 
ATOM   620   C CA  . PRO A 1 99  ? 120.679 90.689  98.161  1.00 49.73 ? 99  PRO A CA  1 
ATOM   621   C C   . PRO A 1 99  ? 120.603 92.190  98.360  1.00 49.73 ? 99  PRO A C   1 
ATOM   622   O O   . PRO A 1 99  ? 121.369 92.947  97.745  1.00 49.73 ? 99  PRO A O   1 
ATOM   623   C CB  . PRO A 1 99  ? 121.616 90.034  99.185  1.00 49.73 ? 99  PRO A CB  1 
ATOM   624   C CG  . PRO A 1 99  ? 122.907 89.911  98.484  1.00 49.73 ? 99  PRO A CG  1 
ATOM   625   C CD  . PRO A 1 99  ? 122.569 89.631  97.064  1.00 49.73 ? 99  PRO A CD  1 
ATOM   626   N N   . PRO A 1 100 ? 119.691 92.662  99.205  1.00 45.35 ? 100 PRO A N   1 
ATOM   627   C CA  . PRO A 1 100 ? 119.556 94.105  99.417  1.00 45.35 ? 100 PRO A CA  1 
ATOM   628   C C   . PRO A 1 100 ? 120.799 94.714  100.042 1.00 45.35 ? 100 PRO A C   1 
ATOM   629   O O   . PRO A 1 100 ? 121.613 94.033  100.666 1.00 45.35 ? 100 PRO A O   1 
ATOM   630   C CB  . PRO A 1 100 ? 118.355 94.213  100.360 1.00 45.35 ? 100 PRO A CB  1 
ATOM   631   C CG  . PRO A 1 100 ? 117.611 92.972  100.150 1.00 45.35 ? 100 PRO A CG  1 
ATOM   632   C CD  . PRO A 1 100 ? 118.618 91.911  99.865  1.00 45.35 ? 100 PRO A CD  1 
ATOM   633   N N   . GLY A 1 101 ? 120.936 96.021  99.867  1.00 41.05 ? 101 GLY A N   1 
ATOM   634   C CA  . GLY A 1 101 ? 122.068 96.739  100.383 1.00 41.05 ? 101 GLY A CA  1 
ATOM   635   C C   . GLY A 1 101 ? 123.038 97.069  99.279  1.00 41.05 ? 101 GLY A C   1 
ATOM   636   O O   . GLY A 1 101 ? 122.725 96.954  98.094  1.00 41.05 ? 101 GLY A O   1 
ATOM   637   N N   . PRO A 1 102 ? 124.235 97.497  99.647  1.00 38.66 ? 102 PRO A N   1 
ATOM   638   C CA  . PRO A 1 102 ? 125.248 97.783  98.635  1.00 38.66 ? 102 PRO A CA  1 
ATOM   639   C C   . PRO A 1 102 ? 125.516 96.570  97.766  1.00 38.66 ? 102 PRO A C   1 
ATOM   640   O O   . PRO A 1 102 ? 125.415 95.427  98.206  1.00 38.66 ? 102 PRO A O   1 
ATOM   641   C CB  . PRO A 1 102 ? 126.478 98.153  99.463  1.00 38.66 ? 102 PRO A CB  1 
ATOM   642   C CG  . PRO A 1 102 ? 125.935 98.623  100.732 1.00 38.66 ? 102 PRO A CG  1 
ATOM   643   C CD  . PRO A 1 102 ? 124.684 97.861  100.995 1.00 38.66 ? 102 PRO A CD  1 
ATOM   644   N N   . LEU A 1 103 ? 125.846 96.833  96.509  1.00 41.36 ? 103 LEU A N   1 
ATOM   645   C CA  . LEU A 1 103 ? 126.299 95.770  95.635  1.00 41.36 ? 103 LEU A CA  1 
ATOM   646   C C   . LEU A 1 103 ? 127.669 95.270  96.034  1.00 41.36 ? 103 LEU A C   1 
ATOM   647   O O   . LEU A 1 103 ? 128.053 94.167  95.640  1.00 41.36 ? 103 LEU A O   1 
ATOM   648   C CB  . LEU A 1 103 ? 126.343 96.248  94.189  1.00 41.36 ? 103 LEU A CB  1 
ATOM   649   C CG  . LEU A 1 103 ? 125.013 96.700  93.598  1.00 41.36 ? 103 LEU A CG  1 
ATOM   650   C CD1 . LEU A 1 103 ? 125.210 97.160  92.173  1.00 41.36 ? 103 LEU A CD1 1 
ATOM   651   C CD2 . LEU A 1 103 ? 123.996 95.596  93.671  1.00 41.36 ? 103 LEU A CD2 1 
ATOM   652   N N   . GLU A 1 104 ? 128.402 96.053  96.811  1.00 47.13 ? 104 GLU A N   1 
ATOM   653   C CA  . GLU A 1 104 ? 129.742 95.685  97.231  1.00 47.13 ? 104 GLU A CA  1 
ATOM   654   C C   . GLU A 1 104 ? 130.245 96.756  98.186  1.00 47.13 ? 104 GLU A C   1 
ATOM   655   O O   . GLU A 1 104 ? 129.701 97.859  98.259  1.00 47.13 ? 104 GLU A O   1 
ATOM   656   C CB  . GLU A 1 104 ? 130.684 95.555  96.043  1.00 47.13 ? 104 GLU A CB  1 
ATOM   657   C CG  . GLU A 1 104 ? 130.951 96.883  95.370  1.00 47.13 ? 104 GLU A CG  1 
ATOM   658   C CD  . GLU A 1 104 ? 131.102 96.758  93.874  1.00 47.13 ? 104 GLU A CD  1 
ATOM   659   O OE1 . GLU A 1 104 ? 130.940 95.642  93.352  1.00 47.13 ? 104 GLU A OE1 1 
ATOM   660   O OE2 . GLU A 1 104 ? 131.392 97.771  93.213  1.00 47.13 ? 104 GLU A OE2 1 
ATOM   661   N N   . ALA A 1 105 ? 131.277 96.398  98.937  1.00 45.56 ? 105 ALA A N   1 
ATOM   662   C CA  . ALA A 1 105 ? 132.118 97.341  99.656  1.00 45.56 ? 105 ALA A CA  1 
ATOM   663   C C   . ALA A 1 105 ? 133.530 96.965  99.279  1.00 45.56 ? 105 ALA A C   1 
ATOM   664   O O   . ALA A 1 105 ? 133.988 95.872  99.610  1.00 45.56 ? 105 ALA A O   1 
ATOM   665   C CB  . ALA A 1 105 ? 131.913 97.261  101.165 1.00 45.56 ? 105 ALA A CB  1 
ATOM   666   N N   . SER A 1 106 ? 134.214 97.853  98.593  1.00 48.05 ? 106 SER A N   1 
ATOM   667   C CA  . SER A 1 106 ? 135.180 97.436  97.596  1.00 48.05 ? 106 SER A CA  1 
ATOM   668   C C   . SER A 1 106 ? 136.569 98.012  97.810  1.00 48.05 ? 106 SER A C   1 
ATOM   669   O O   . SER A 1 106 ? 137.147 98.618  96.911  1.00 48.05 ? 106 SER A O   1 
ATOM   670   C CB  . SER A 1 106 ? 134.642 97.759  96.209  1.00 48.05 ? 106 SER A CB  1 
ATOM   671   O OG  . SER A 1 106 ? 134.167 99.084  96.118  1.00 48.05 ? 106 SER A OG  1 
ATOM   672   N N   . VAL A 1 107 ? 137.120 97.812  99.002  1.00 54.79 ? 107 VAL A N   1 
ATOM   673   C CA  . VAL A 1 107 ? 138.501 98.178  99.283  1.00 54.79 ? 107 VAL A CA  1 
ATOM   674   C C   . VAL A 1 107 ? 139.391 97.712  98.142  1.00 54.79 ? 107 VAL A C   1 
ATOM   675   O O   . VAL A 1 107 ? 139.433 96.522  97.817  1.00 54.79 ? 107 VAL A O   1 
ATOM   676   C CB  . VAL A 1 107 ? 138.983 97.559  100.604 1.00 54.79 ? 107 VAL A CB  1 
ATOM   677   C CG1 . VAL A 1 107 ? 140.456 97.803  100.779 1.00 54.79 ? 107 VAL A CG1 1 
ATOM   678   C CG2 . VAL A 1 107 ? 138.210 98.122  101.753 1.00 54.79 ? 107 VAL A CG2 1 
ATOM   679   N N   . ASN A 1 108 ? 140.118 98.645  97.541  1.00 62.37 ? 108 ASN A N   1 
ATOM   680   C CA  . ASN A 1 108 ? 141.022 98.354  96.444  1.00 62.37 ? 108 ASN A CA  1 
ATOM   681   C C   . ASN A 1 108 ? 142.459 98.542  96.886  1.00 62.37 ? 108 ASN A C   1 
ATOM   682   O O   . ASN A 1 108 ? 142.770 99.460  97.654  1.00 62.37 ? 108 ASN A O   1 
ATOM   683   C CB  . ASN A 1 108 ? 140.757 99.261  95.254  1.00 62.37 ? 108 ASN A CB  1 
ATOM   684   C CG  . ASN A 1 108 ? 141.862 99.203  94.233  1.00 62.37 ? 108 ASN A CG  1 
ATOM   685   O OD1 . ASN A 1 108 ? 142.649 98.260  94.197  1.00 62.37 ? 108 ASN A OD1 1 
ATOM   686   N ND2 . ASN A 1 108 ? 141.957 100.238 93.421  1.00 62.37 ? 108 ASN A ND2 1 
ATOM   687   N N   . TYR A 1 109 ? 143.329 97.693  96.344  1.00 67.07 ? 109 TYR A N   1 
ATOM   688   C CA  . TYR A 1 109 ? 144.743 97.650  96.685  1.00 67.07 ? 109 TYR A CA  1 
ATOM   689   C C   . TYR A 1 109 ? 145.570 97.939  95.445  1.00 67.07 ? 109 TYR A C   1 
ATOM   690   O O   . TYR A 1 109 ? 145.300 97.387  94.375  1.00 67.07 ? 109 TYR A O   1 
ATOM   691   C CB  . TYR A 1 109 ? 145.128 96.281  97.262  1.00 67.07 ? 109 TYR A CB  1 
ATOM   692   C CG  . TYR A 1 109 ? 144.225 95.815  98.375  1.00 67.07 ? 109 TYR A CG  1 
ATOM   693   C CD1 . TYR A 1 109 ? 143.017 95.190  98.105  1.00 67.07 ? 109 TYR A CD1 1 
ATOM   694   C CD2 . TYR A 1 109 ? 144.571 96.014  99.696  1.00 67.07 ? 109 TYR A CD2 1 
ATOM   695   C CE1 . TYR A 1 109 ? 142.192 94.779  99.123  1.00 67.07 ? 109 TYR A CE1 1 
ATOM   696   C CE2 . TYR A 1 109 ? 143.756 95.599  100.715 1.00 67.07 ? 109 TYR A CE2 1 
ATOM   697   C CZ  . TYR A 1 109 ? 142.568 94.988  100.427 1.00 67.07 ? 109 TYR A CZ  1 
ATOM   698   O OH  . TYR A 1 109 ? 141.760 94.584  101.457 1.00 67.07 ? 109 TYR A OH  1 
ATOM   699   N N   . GLN A 1 110 ? 146.571 98.802  95.589  1.00 72.65 ? 110 GLN A N   1 
ATOM   700   C CA  . GLN A 1 110 ? 147.550 99.023  94.540  1.00 72.65 ? 110 GLN A CA  1 
ATOM   701   C C   . GLN A 1 110 ? 148.918 99.120  95.191  1.00 72.65 ? 110 GLN A C   1 
ATOM   702   O O   . GLN A 1 110 ? 149.039 99.217  96.416  1.00 72.65 ? 110 GLN A O   1 
ATOM   703   C CB  . GLN A 1 110 ? 147.235 100.282 93.730  1.00 72.65 ? 110 GLN A CB  1 
ATOM   704   C CG  . GLN A 1 110 ? 145.807 100.396 93.260  1.00 72.65 ? 110 GLN A CG  1 
ATOM   705   C CD  . GLN A 1 110 ? 145.425 101.820 92.958  1.00 72.65 ? 110 GLN A CD  1 
ATOM   706   O OE1 . GLN A 1 110 ? 145.919 102.418 92.005  1.00 72.65 ? 110 GLN A OE1 1 
ATOM   707   N NE2 . GLN A 1 110 ? 144.549 102.381 93.781  1.00 72.65 ? 110 GLN A NE2 1 
ATOM   708   N N   . ALA A 1 111 ? 149.950 99.137  94.356  1.00 75.94 ? 111 ALA A N   1 
ATOM   709   C CA  . ALA A 1 111 ? 151.322 99.073  94.834  1.00 75.94 ? 111 ALA A CA  1 
ATOM   710   C C   . ALA A 1 111 ? 151.666 100.281 95.698  1.00 75.94 ? 111 ALA A C   1 
ATOM   711   O O   . ALA A 1 111 ? 150.914 101.255 95.786  1.00 75.94 ? 111 ALA A O   1 
ATOM   712   C CB  . ALA A 1 111 ? 152.292 98.984  93.657  1.00 75.94 ? 111 ALA A CB  1 
ATOM   713   N N   . GLY A 1 112 ? 152.830 100.204 96.334  1.00 80.13 ? 112 GLY A N   1 
ATOM   714   C CA  . GLY A 1 112 ? 153.246 101.242 97.257  1.00 80.13 ? 112 GLY A CA  1 
ATOM   715   C C   . GLY A 1 112 ? 152.335 101.355 98.455  1.00 80.13 ? 112 GLY A C   1 
ATOM   716   O O   . GLY A 1 112 ? 152.271 102.417 99.087  1.00 80.13 ? 112 GLY A O   1 
ATOM   717   N N   . GLU A 1 113 ? 151.628 100.274 98.785  1.00 81.04 ? 113 GLU A N   1 
ATOM   718   C CA  . GLU A 1 113 ? 150.636 100.268 99.856  1.00 81.04 ? 113 GLU A CA  1 
ATOM   719   C C   . GLU A 1 113 ? 149.643 101.412 99.684  1.00 81.04 ? 113 GLU A C   1 
ATOM   720   O O   . GLU A 1 113 ? 149.457 102.244 100.574 1.00 81.04 ? 113 GLU A O   1 
ATOM   721   C CB  . GLU A 1 113 ? 151.301 100.317 101.229 1.00 81.04 ? 113 GLU A CB  1 
ATOM   722   C CG  . GLU A 1 113 ? 152.032 99.043  101.595 1.00 81.04 ? 113 GLU A CG  1 
ATOM   723   C CD  . GLU A 1 113 ? 153.191 99.296  102.530 1.00 81.04 ? 113 GLU A CD  1 
ATOM   724   O OE1 . GLU A 1 113 ? 153.493 100.480 102.790 1.00 81.04 ? 113 GLU A OE1 1 
ATOM   725   O OE2 . GLU A 1 113 ? 153.808 98.315  102.993 1.00 81.04 ? 113 GLU A OE2 1 
ATOM   726   N N   . SER A 1 114 ? 149.005 101.463 98.517  1.00 73.64 ? 114 SER A N   1 
ATOM   727   C CA  . SER A 1 114 ? 147.996 102.477 98.229  1.00 73.64 ? 114 SER A CA  1 
ATOM   728   C C   . SER A 1 114 ? 146.638 101.789 98.160  1.00 73.64 ? 114 SER A C   1 
ATOM   729   O O   . SER A 1 114 ? 146.226 101.284 97.114  1.00 73.64 ? 114 SER A O   1 
ATOM   730   C CB  . SER A 1 114 ? 148.318 103.220 96.938  1.00 73.64 ? 114 SER A CB  1 
ATOM   731   O OG  . SER A 1 114 ? 147.211 103.990 96.520  1.00 73.64 ? 114 SER A OG  1 
ATOM   732   N N   . SER A 1 115 ? 145.956 101.751 99.294  1.00 61.81 ? 115 SER A N   1 
ATOM   733   C CA  . SER A 1 115 ? 144.651 101.129 99.411  1.00 61.81 ? 115 SER A CA  1 
ATOM   734   C C   . SER A 1 115 ? 143.612 102.201 99.684  1.00 61.81 ? 115 SER A C   1 
ATOM   735   O O   . SER A 1 115 ? 143.841 103.106 100.486 1.00 61.81 ? 115 SER A O   1 
ATOM   736   C CB  . SER A 1 115 ? 144.645 100.103 100.534 1.00 61.81 ? 115 SER A CB  1 
ATOM   737   O OG  . SER A 1 115 ? 144.882 100.739 101.771 1.00 61.81 ? 115 SER A OG  1 
ATOM   738   N N   . MET A 1 116 ? 142.475 102.102 99.019  1.00 53.51 ? 116 MET A N   1 
ATOM   739   C CA  . MET A 1 116 ? 141.424 103.081 99.232  1.00 53.51 ? 116 MET A CA  1 
ATOM   740   C C   . MET A 1 116 ? 140.062 102.406 99.257  1.00 53.51 ? 116 MET A C   1 
ATOM   741   O O   . MET A 1 116 ? 139.869 101.323 98.703  1.00 53.51 ? 116 MET A O   1 
ATOM   742   C CB  . MET A 1 116 ? 141.449 104.172 98.173  1.00 53.51 ? 116 MET A CB  1 
ATOM   743   C CG  . MET A 1 116 ? 141.276 103.676 96.775  1.00 53.51 ? 116 MET A CG  1 
ATOM   744   S SD  . MET A 1 116 ? 140.629 104.968 95.690  1.00 53.51 ? 116 MET A SD  1 
ATOM   745   C CE  . MET A 1 116 ? 138.992 105.202 96.380  1.00 53.51 ? 116 MET A CE  1 
ATOM   746   N N   . PHE A 1 117 ? 139.121 103.063 99.918  1.00 44.04 ? 117 PHE A N   1 
ATOM   747   C CA  . PHE A 1 117 ? 137.793 102.523 100.147 1.00 44.04 ? 117 PHE A CA  1 
ATOM   748   C C   . PHE A 1 117 ? 136.823 103.131 99.156  1.00 44.04 ? 117 PHE A C   1 
ATOM   749   O O   . PHE A 1 117 ? 136.904 104.321 98.826  1.00 44.04 ? 117 PHE A O   1 
ATOM   750   C CB  . PHE A 1 117 ? 137.330 102.801 101.576 1.00 44.04 ? 117 PHE A CB  1 
ATOM   751   C CG  . PHE A 1 117 ? 135.972 102.243 101.914 1.00 44.04 ? 117 PHE A CG  1 
ATOM   752   C CD1 . PHE A 1 117 ? 135.831 100.944 102.350 1.00 44.04 ? 117 PHE A CD1 1 
ATOM   753   C CD2 . PHE A 1 117 ? 134.842 103.034 101.838 1.00 44.04 ? 117 PHE A CD2 1 
ATOM   754   C CE1 . PHE A 1 117 ? 134.594 100.445 102.672 1.00 44.04 ? 117 PHE A CE1 1 
ATOM   755   C CE2 . PHE A 1 117 ? 133.605 102.532 102.167 1.00 44.04 ? 117 PHE A CE2 1 
ATOM   756   C CZ  . PHE A 1 117 ? 133.485 101.243 102.581 1.00 44.04 ? 117 PHE A CZ  1 
ATOM   757   N N   . ARG A 1 118 ? 135.909 102.311 98.687  1.00 49.21 ? 118 ARG A N   1 
ATOM   758   C CA  . ARG A 1 118 ? 134.931 102.699 97.699  1.00 49.21 ? 118 ARG A CA  1 
ATOM   759   C C   . ARG A 1 118 ? 133.747 101.766 97.860  1.00 49.21 ? 118 ARG A C   1 
ATOM   760   O O   . ARG A 1 118 ? 133.857 100.677 98.421  1.00 49.21 ? 118 ARG A O   1 
ATOM   761   C CB  . ARG A 1 118 ? 135.524 102.653 96.283  1.00 49.21 ? 118 ARG A CB  1 
ATOM   762   C CG  . ARG A 1 118 ? 136.047 101.301 95.890  1.00 49.21 ? 118 ARG A CG  1 
ATOM   763   C CD  . ARG A 1 118 ? 136.672 101.228 94.509  1.00 49.21 ? 118 ARG A CD  1 
ATOM   764   N NE  . ARG A 1 118 ? 138.106 101.502 94.483  1.00 49.21 ? 118 ARG A NE  1 
ATOM   765   C CZ  . ARG A 1 118 ? 138.661 102.539 93.865  1.00 49.21 ? 118 ARG A CZ  1 
ATOM   766   N NH1 . ARG A 1 118 ? 137.903 103.417 93.229  1.00 49.21 ? 118 ARG A NH1 1 
ATOM   767   N NH2 . ARG A 1 118 ? 139.974 102.699 93.879  1.00 49.21 ? 118 ARG A NH2 1 
ATOM   768   N N   . PHE A 1 119 ? 132.599 102.201 97.379  1.00 40.02 ? 119 PHE A N   1 
ATOM   769   C CA  . PHE A 1 119 ? 131.368 101.566 97.820  1.00 40.02 ? 119 PHE A CA  1 
ATOM   770   C C   . PHE A 1 119 ? 130.301 101.789 96.770  1.00 40.02 ? 119 PHE A C   1 
ATOM   771   O O   . PHE A 1 119 ? 130.050 102.925 96.379  1.00 40.02 ? 119 PHE A O   1 
ATOM   772   C CB  . PHE A 1 119 ? 130.996 102.129 99.185  1.00 40.02 ? 119 PHE A CB  1 
ATOM   773   C CG  . PHE A 1 119 ? 129.568 102.499 99.342  1.00 40.02 ? 119 PHE A CG  1 
ATOM   774   C CD1 . PHE A 1 119 ? 128.568 101.559 99.290  1.00 40.02 ? 119 PHE A CD1 1 
ATOM   775   C CD2 . PHE A 1 119 ? 129.234 103.809 99.592  1.00 40.02 ? 119 PHE A CD2 1 
ATOM   776   C CE1 . PHE A 1 119 ? 127.262 101.932 99.444  1.00 40.02 ? 119 PHE A CE1 1 
ATOM   777   C CE2 . PHE A 1 119 ? 127.938 104.178 99.751  1.00 40.02 ? 119 PHE A CE2 1 
ATOM   778   C CZ  . PHE A 1 119 ? 126.950 103.243 99.679  1.00 40.02 ? 119 PHE A CZ  1 
ATOM   779   N N   . THR A 1 120 ? 129.696 100.708 96.297  1.00 39.76 ? 120 THR A N   1 
ATOM   780   C CA  . THR A 1 120 ? 128.745 100.758 95.199  1.00 39.76 ? 120 THR A CA  1 
ATOM   781   C C   . THR A 1 120 ? 127.343 100.550 95.733  1.00 39.76 ? 120 THR A C   1 
ATOM   782   O O   . THR A 1 120 ? 127.124 99.691  96.586  1.00 39.76 ? 120 THR A O   1 
ATOM   783   C CB  . THR A 1 120 ? 129.058 99.693  94.153  1.00 39.76 ? 120 THR A CB  1 
ATOM   784   O OG1 . THR A 1 120 ? 130.391 99.877  93.674  1.00 39.76 ? 120 THR A OG1 1 
ATOM   785   C CG2 . THR A 1 120 ? 128.108 99.800  92.988  1.00 39.76 ? 120 THR A CG2 1 
ATOM   786   N N   . ILE A 1 121 ? 126.398 101.320 95.220  1.00 39.05 ? 121 ILE A N   1 
ATOM   787   C CA  . ILE A 1 121 ? 125.008 101.159 95.591  1.00 39.05 ? 121 ILE A CA  1 
ATOM   788   C C   . ILE A 1 121 ? 124.146 101.455 94.377  1.00 39.05 ? 121 ILE A C   1 
ATOM   789   O O   . ILE A 1 121 ? 124.448 102.351 93.583  1.00 39.05 ? 121 ILE A O   1 
ATOM   790   C CB  . ILE A 1 121 ? 124.644 102.068 96.779  1.00 39.05 ? 121 ILE A CB  1 
ATOM   791   C CG1 . ILE A 1 121 ? 123.145 102.031 97.048  1.00 39.05 ? 121 ILE A CG1 1 
ATOM   792   C CG2 . ILE A 1 121 ? 125.097 103.477 96.535  1.00 39.05 ? 121 ILE A CG2 1 
ATOM   793   C CD1 . ILE A 1 121 ? 122.739 102.808 98.253  1.00 39.05 ? 121 ILE A CD1 1 
ATOM   794   N N   . GLU A 1 122 ? 123.099 100.680 94.215  1.00 41.18 ? 122 GLU A N   1 
ATOM   795   C CA  . GLU A 1 122 ? 122.040 101.048 93.300  1.00 41.18 ? 122 GLU A CA  1 
ATOM   796   C C   . GLU A 1 122 ? 121.059 101.871 94.120  1.00 41.18 ? 122 GLU A C   1 
ATOM   797   O O   . GLU A 1 122 ? 120.277 101.303 94.888  1.00 41.18 ? 122 GLU A O   1 
ATOM   798   C CB  . GLU A 1 122 ? 121.395 99.802  92.693  1.00 41.18 ? 122 GLU A CB  1 
ATOM   799   C CG  . GLU A 1 122 ? 120.577 100.030 91.436  1.00 41.18 ? 122 GLU A CG  1 
ATOM   800   C CD  . GLU A 1 122 ? 119.080 99.993  91.674  1.00 41.18 ? 122 GLU A CD  1 
ATOM   801   O OE1 . GLU A 1 122 ? 118.634 99.245  92.567  1.00 41.18 ? 122 GLU A OE1 1 
ATOM   802   O OE2 . GLU A 1 122 ? 118.343 100.705 90.961  1.00 41.18 ? 122 GLU A OE2 1 
ATOM   803   N N   . PRO A 1 123 ? 121.097 103.207 94.026  1.00 39.66 ? 123 PRO A N   1 
ATOM   804   C CA  . PRO A 1 123 ? 120.227 104.027 94.872  1.00 39.66 ? 123 PRO A CA  1 
ATOM   805   C C   . PRO A 1 123 ? 118.780 103.618 94.754  1.00 39.66 ? 123 PRO A C   1 
ATOM   806   O O   . PRO A 1 123 ? 118.215 103.634 93.661  1.00 39.66 ? 123 PRO A O   1 
ATOM   807   C CB  . PRO A 1 123 ? 120.451 105.440 94.336  1.00 39.66 ? 123 PRO A CB  1 
ATOM   808   C CG  . PRO A 1 123 ? 121.778 105.398 93.737  1.00 39.66 ? 123 PRO A CG  1 
ATOM   809   C CD  . PRO A 1 123 ? 121.932 104.043 93.150  1.00 39.66 ? 123 PRO A CD  1 
ATOM   810   N N   . VAL A 1 124 ? 118.183 103.230 95.870  1.00 37.62 ? 124 VAL A N   1 
ATOM   811   C CA  . VAL A 1 124 ? 116.806 102.771 95.913  1.00 37.62 ? 124 VAL A CA  1 
ATOM   812   C C   . VAL A 1 124 ? 116.017 103.743 96.769  1.00 37.62 ? 124 VAL A C   1 
ATOM   813   O O   . VAL A 1 124 ? 116.411 104.041 97.898  1.00 37.62 ? 124 VAL A O   1 
ATOM   814   C CB  . VAL A 1 124 ? 116.707 101.344 96.472  1.00 37.62 ? 124 VAL A CB  1 
ATOM   815   C CG1 . VAL A 1 124 ? 115.279 100.975 96.708  1.00 37.62 ? 124 VAL A CG1 1 
ATOM   816   C CG2 . VAL A 1 124 ? 117.323 100.384 95.517  1.00 37.62 ? 124 VAL A CG2 1 
ATOM   817   N N   . GLY A 1 125 ? 114.921 104.245 96.232  1.00 38.78 ? 125 GLY A N   1 
ATOM   818   C CA  . GLY A 1 125 ? 114.047 105.082 97.005  1.00 38.78 ? 125 GLY A CA  1 
ATOM   819   C C   . GLY A 1 125 ? 113.369 104.267 98.075  1.00 38.78 ? 125 GLY A C   1 
ATOM   820   O O   . GLY A 1 125 ? 113.245 103.048 97.964  1.00 38.78 ? 125 GLY A O   1 
ATOM   821   N N   . PRO A 1 126 ? 112.912 104.921 99.140  1.00 38.97 ? 126 PRO A N   1 
ATOM   822   C CA  . PRO A 1 126 ? 112.201 104.185 100.189 1.00 38.97 ? 126 PRO A CA  1 
ATOM   823   C C   . PRO A 1 126 ? 110.964 103.487 99.686  1.00 38.97 ? 126 PRO A C   1 
ATOM   824   O O   . PRO A 1 126 ? 110.437 102.615 100.385 1.00 38.97 ? 126 PRO A O   1 
ATOM   825   C CB  . PRO A 1 126 ? 111.853 105.276 101.205 1.00 38.97 ? 126 PRO A CB  1 
ATOM   826   C CG  . PRO A 1 126 ? 111.877 106.523 100.434 1.00 38.97 ? 126 PRO A CG  1 
ATOM   827   C CD  . PRO A 1 126 ? 112.960 106.359 99.426  1.00 38.97 ? 126 PRO A CD  1 
ATOM   828   N N   . HIS A 1 127 ? 110.480 103.836 98.495  1.00 44.29 ? 127 HIS A N   1 
ATOM   829   C CA  . HIS A 1 127 ? 109.314 103.190 97.910  1.00 44.29 ? 127 HIS A CA  1 
ATOM   830   C C   . HIS A 1 127 ? 109.567 102.761 96.472  1.00 44.29 ? 127 HIS A C   1 
ATOM   831   O O   . HIS A 1 127 ? 108.618 102.614 95.705  1.00 44.29 ? 127 HIS A O   1 
ATOM   832   C CB  . HIS A 1 127 ? 108.101 104.113 97.987  1.00 44.29 ? 127 HIS A CB  1 
ATOM   833   C CG  . HIS A 1 127 ? 107.982 104.827 99.294  1.00 44.29 ? 127 HIS A CG  1 
ATOM   834   N ND1 . HIS A 1 127 ? 107.808 104.162 100.487 1.00 44.29 ? 127 HIS A ND1 1 
ATOM   835   C CD2 . HIS A 1 127 ? 108.022 106.143 99.600  1.00 44.29 ? 127 HIS A CD2 1 
ATOM   836   C CE1 . HIS A 1 127 ? 107.745 105.038 101.472 1.00 44.29 ? 127 HIS A CE1 1 
ATOM   837   N NE2 . HIS A 1 127 ? 107.873 106.248 100.961 1.00 44.29 ? 127 HIS A NE2 1 
ATOM   838   N N   . ALA A 1 128 ? 110.823 102.557 96.097  1.00 43.24 ? 128 ALA A N   1 
ATOM   839   C CA  . ALA A 1 128 ? 111.147 102.137 94.745  1.00 43.24 ? 128 ALA A CA  1 
ATOM   840   C C   . ALA A 1 128 ? 110.636 100.730 94.487  1.00 43.24 ? 128 ALA A C   1 
ATOM   841   O O   . ALA A 1 128 ? 110.696 99.858  95.350  1.00 43.24 ? 128 ALA A O   1 
ATOM   842   C CB  . ALA A 1 128 ? 112.650 102.185 94.522  1.00 43.24 ? 128 ALA A CB  1 
ATOM   843   N N   . GLY A 1 129 ? 110.143 100.507 93.278  1.00 44.53 ? 129 GLY A N   1 
ATOM   844   C CA  . GLY A 1 129 ? 109.524 99.242  92.972  1.00 44.53 ? 129 GLY A CA  1 
ATOM   845   C C   . GLY A 1 129 ? 108.094 99.122  93.428  1.00 44.53 ? 129 GLY A C   1 
ATOM   846   O O   . GLY A 1 129 ? 107.542 98.019  93.399  1.00 44.53 ? 129 GLY A O   1 
ATOM   847   N N   . THR A 1 130 ? 107.485 100.216 93.851  1.00 46.21 ? 130 THR A N   1 
ATOM   848   C CA  . THR A 1 130 ? 106.086 100.289 94.226  1.00 46.21 ? 130 THR A CA  1 
ATOM   849   C C   . THR A 1 130 ? 105.403 101.332 93.355  1.00 46.21 ? 130 THR A C   1 
ATOM   850   O O   . THR A 1 130 ? 106.073 102.162 92.736  1.00 46.21 ? 130 THR A O   1 
ATOM   851   C CB  . THR A 1 130 ? 105.952 100.650 95.709  1.00 46.21 ? 130 THR A CB  1 
ATOM   852   O OG1 . THR A 1 130 ? 106.754 101.799 95.990  1.00 46.21 ? 130 THR A OG1 1 
ATOM   853   C CG2 . THR A 1 130 ? 106.424 99.502  96.568  1.00 46.21 ? 130 THR A CG2 1 
ATOM   854   N N   . PRO A 1 131 ? 104.068 101.318 93.274  1.00 49.52 ? 131 PRO A N   1 
ATOM   855   C CA  . PRO A 1 131 ? 103.395 102.209 92.318  1.00 49.52 ? 131 PRO A CA  1 
ATOM   856   C C   . PRO A 1 131 ? 103.642 103.680 92.558  1.00 49.52 ? 131 PRO A C   1 
ATOM   857   O O   . PRO A 1 131 ? 103.228 104.498 91.731  1.00 49.52 ? 131 PRO A O   1 
ATOM   858   C CB  . PRO A 1 131 ? 101.915 101.858 92.498  1.00 49.52 ? 131 PRO A CB  1 
ATOM   859   C CG  . PRO A 1 131 ? 101.925 100.483 93.022  1.00 49.52 ? 131 PRO A CG  1 
ATOM   860   C CD  . PRO A 1 131 ? 103.109 100.418 93.929  1.00 49.52 ? 131 PRO A CD  1 
ATOM   861   N N   . ALA A 1 132 ? 104.290 104.053 93.661  1.00 48.40 ? 132 ALA A N   1 
ATOM   862   C CA  . ALA A 1 132 ? 104.672 105.445 93.862  1.00 48.40 ? 132 ALA A CA  1 
ATOM   863   C C   . ALA A 1 132 ? 106.014 105.768 93.223  1.00 48.40 ? 132 ALA A C   1 
ATOM   864   O O   . ALA A 1 132 ? 106.279 106.933 92.914  1.00 48.40 ? 132 ALA A O   1 
ATOM   865   C CB  . ALA A 1 132 ? 104.715 105.772 95.351  1.00 48.40 ? 132 ALA A CB  1 
ATOM   866   N N   . ASP A 1 133 ? 106.871 104.769 93.025  1.00 46.74 ? 133 ASP A N   1 
ATOM   867   C CA  . ASP A 1 133 ? 108.168 104.956 92.375  1.00 46.74 ? 133 ASP A CA  1 
ATOM   868   C C   . ASP A 1 133 ? 108.522 103.696 91.604  1.00 46.74 ? 133 ASP A C   1 
ATOM   869   O O   . ASP A 1 133 ? 109.469 102.981 91.941  1.00 46.74 ? 133 ASP A O   1 
ATOM   870   C CB  . ASP A 1 133 ? 109.247 105.293 93.405  1.00 46.74 ? 133 ASP A CB  1 
ATOM   871   C CG  . ASP A 1 133 ? 110.511 105.826 92.774  1.00 46.74 ? 133 ASP A CG  1 
ATOM   872   O OD1 . ASP A 1 133 ? 110.600 105.843 91.531  1.00 46.74 ? 133 ASP A OD1 1 
ATOM   873   O OD2 . ASP A 1 133 ? 111.422 106.235 93.523  1.00 46.74 ? 133 ASP A OD2 1 
ATOM   874   N N   . PRO A 1 134 ? 107.784 103.403 90.529  1.00 46.42 ? 134 PRO A N   1 
ATOM   875   C CA  . PRO A 1 134 ? 107.969 102.118 89.846  1.00 46.42 ? 134 PRO A CA  1 
ATOM   876   C C   . PRO A 1 134 ? 109.308 101.959 89.158  1.00 46.42 ? 134 PRO A C   1 
ATOM   877   O O   . PRO A 1 134 ? 109.685 100.824 88.853  1.00 46.42 ? 134 PRO A O   1 
ATOM   878   C CB  . PRO A 1 134 ? 106.824 102.098 88.830  1.00 46.42 ? 134 PRO A CB  1 
ATOM   879   C CG  . PRO A 1 134 ? 106.470 103.511 88.633  1.00 46.42 ? 134 PRO A CG  1 
ATOM   880   C CD  . PRO A 1 134 ? 106.685 104.182 89.942  1.00 46.42 ? 134 PRO A CD  1 
ATOM   881   N N   . VAL A 1 135 ? 110.043 103.035 88.896  1.00 46.72 ? 135 VAL A N   1 
ATOM   882   C CA  . VAL A 1 135 ? 111.298 102.924 88.171  1.00 46.72 ? 135 VAL A CA  1 
ATOM   883   C C   . VAL A 1 135 ? 112.468 103.501 88.945  1.00 46.72 ? 135 VAL A C   1 
ATOM   884   O O   . VAL A 1 135 ? 113.557 103.636 88.391  1.00 46.72 ? 135 VAL A O   1 
ATOM   885   C CB  . VAL A 1 135 ? 111.201 103.577 86.782  1.00 46.72 ? 135 VAL A CB  1 
ATOM   886   C CG1 . VAL A 1 135 ? 110.434 102.682 85.848  1.00 46.72 ? 135 VAL A CG1 1 
ATOM   887   C CG2 . VAL A 1 135 ? 110.528 104.918 86.895  1.00 46.72 ? 135 VAL A CG2 1 
ATOM   888   N N   . ASN A 1 136 ? 112.268 103.855 90.211  1.00 43.12 ? 136 ASN A N   1 
ATOM   889   C CA  . ASN A 1 136 ? 113.353 104.316 91.067  1.00 43.12 ? 136 ASN A CA  1 
ATOM   890   C C   . ASN A 1 136 ? 114.077 105.501 90.428  1.00 43.12 ? 136 ASN A C   1 
ATOM   891   O O   . ASN A 1 136 ? 115.282 105.476 90.179  1.00 43.12 ? 136 ASN A O   1 
ATOM   892   C CB  . ASN A 1 136 ? 114.312 103.162 91.360  1.00 43.12 ? 136 ASN A CB  1 
ATOM   893   C CG  . ASN A 1 136 ? 115.254 103.460 92.483  1.00 43.12 ? 136 ASN A CG  1 
ATOM   894   O OD1 . ASN A 1 136 ? 114.899 104.130 93.442  1.00 43.12 ? 136 ASN A OD1 1 
ATOM   895   N ND2 . ASN A 1 136 ? 116.469 102.958 92.376  1.00 43.12 ? 136 ASN A ND2 1 
ATOM   896   N N   . GLU A 1 137 ? 113.312 106.555 90.166  1.00 47.67 ? 137 GLU A N   1 
ATOM   897   C CA  . GLU A 1 137 ? 113.814 107.679 89.386  1.00 47.67 ? 137 GLU A CA  1 
ATOM   898   C C   . GLU A 1 137 ? 114.569 108.708 90.218  1.00 47.67 ? 137 GLU A C   1 
ATOM   899   O O   . GLU A 1 137 ? 115.615 109.201 89.787  1.00 47.67 ? 137 GLU A O   1 
ATOM   900   C CB  . GLU A 1 137 ? 112.654 108.357 88.667  1.00 47.67 ? 137 GLU A CB  1 
ATOM   901   C CG  . GLU A 1 137 ? 111.411 108.453 89.511  1.00 47.67 ? 137 GLU A CG  1 
ATOM   902   C CD  . GLU A 1 137 ? 110.408 109.431 88.951  1.00 47.67 ? 137 GLU A CD  1 
ATOM   903   O OE1 . GLU A 1 137 ? 110.756 110.170 88.009  1.00 47.67 ? 137 GLU A OE1 1 
ATOM   904   O OE2 . GLU A 1 137 ? 109.269 109.462 89.454  1.00 47.67 ? 137 GLU A OE2 1 
ATOM   905   N N   . LEU A 1 138 ? 114.064 109.049 91.401  1.00 43.60 ? 138 LEU A N   1 
ATOM   906   C CA  . LEU A 1 138 ? 114.607 110.183 92.135  1.00 43.60 ? 138 LEU A CA  1 
ATOM   907   C C   . LEU A 1 138 ? 115.886 109.837 92.873  1.00 43.60 ? 138 LEU A C   1 
ATOM   908   O O   . LEU A 1 138 ? 116.796 110.663 92.938  1.00 43.60 ? 138 LEU A O   1 
ATOM   909   C CB  . LEU A 1 138 ? 113.578 110.713 93.125  1.00 43.60 ? 138 LEU A CB  1 
ATOM   910   C CG  . LEU A 1 138 ? 112.384 111.436 92.524  1.00 43.60 ? 138 LEU A CG  1 
ATOM   911   C CD1 . LEU A 1 138 ? 111.605 112.114 93.615  1.00 43.60 ? 138 LEU A CD1 1 
ATOM   912   C CD2 . LEU A 1 138 ? 112.848 112.443 91.506  1.00 43.60 ? 138 LEU A CD2 1 
ATOM   913   N N   . ALA A 1 139 ? 115.973 108.625 93.420  1.00 42.02 ? 139 ALA A N   1 
ATOM   914   C CA  . ALA A 1 139 ? 117.009 108.303 94.397  1.00 42.02 ? 139 ALA A CA  1 
ATOM   915   C C   . ALA A 1 139 ? 118.389 108.738 93.940  1.00 42.02 ? 139 ALA A C   1 
ATOM   916   O O   . ALA A 1 139 ? 119.144 109.334 94.712  1.00 42.02 ? 139 ALA A O   1 
ATOM   917   C CB  . ALA A 1 139 ? 116.998 106.809 94.689  1.00 42.02 ? 139 ALA A CB  1 
ATOM   918   N N   . ALA A 1 140 ? 118.733 108.470 92.682  1.00 41.98 ? 140 ALA A N   1 
ATOM   919   C CA  . ALA A 1 140 ? 120.060 108.830 92.196  1.00 41.98 ? 140 ALA A CA  1 
ATOM   920   C C   . ALA A 1 140 ? 120.253 110.339 92.179  1.00 41.98 ? 140 ALA A C   1 
ATOM   921   O O   . ALA A 1 140 ? 121.317 110.841 92.556  1.00 41.98 ? 140 ALA A O   1 
ATOM   922   C CB  . ALA A 1 140 ? 120.280 108.246 90.808  1.00 41.98 ? 140 ALA A CB  1 
ATOM   923   N N   . LYS A 1 141 ? 119.226 111.079 91.765  1.00 44.13 ? 141 LYS A N   1 
ATOM   924   C CA  . LYS A 1 141 ? 119.342 112.529 91.701  1.00 44.13 ? 141 LYS A CA  1 
ATOM   925   C C   . LYS A 1 141 ? 119.360 113.149 93.089  1.00 44.13 ? 141 LYS A C   1 
ATOM   926   O O   . LYS A 1 141 ? 120.086 114.114 93.328  1.00 44.13 ? 141 LYS A O   1 
ATOM   927   C CB  . LYS A 1 141 ? 118.204 113.101 90.872  1.00 44.13 ? 141 LYS A CB  1 
ATOM   928   C CG  . LYS A 1 141 ? 118.328 112.789 89.411  1.00 44.13 ? 141 LYS A CG  1 
ATOM   929   C CD  . LYS A 1 141 ? 117.053 113.123 88.694  1.00 44.13 ? 141 LYS A CD  1 
ATOM   930   C CE  . LYS A 1 141 ? 117.181 112.876 87.217  1.00 44.13 ? 141 LYS A CE  1 
ATOM   931   N NZ  . LYS A 1 141 ? 115.862 113.025 86.558  1.00 44.13 ? 141 LYS A NZ  1 
ATOM   932   N N   . GLN A 1 142 ? 118.560 112.620 94.013  1.00 43.10 ? 142 GLN A N   1 
ATOM   933   C CA  . GLN A 1 142 ? 118.626 113.081 95.394  1.00 43.10 ? 142 GLN A CA  1 
ATOM   934   C C   . GLN A 1 142 ? 120.001 112.835 95.985  1.00 43.10 ? 142 GLN A C   1 
ATOM   935   O O   . GLN A 1 142 ? 120.541 113.688 96.691  1.00 43.10 ? 142 GLN A O   1 
ATOM   936   C CB  . GLN A 1 142 ? 117.564 112.388 96.233  1.00 43.10 ? 142 GLN A CB  1 
ATOM   937   C CG  . GLN A 1 142 ? 116.168 112.821 95.926  1.00 43.10 ? 142 GLN A CG  1 
ATOM   938   C CD  . GLN A 1 142 ? 115.162 112.073 96.743  1.00 43.10 ? 142 GLN A CD  1 
ATOM   939   O OE1 . GLN A 1 142 ? 115.498 111.111 97.418  1.00 43.10 ? 142 GLN A OE1 1 
ATOM   940   N NE2 . GLN A 1 142 ? 113.919 112.508 96.693  1.00 43.10 ? 142 GLN A NE2 1 
ATOM   941   N N   . LEU A 1 143 ? 120.583 111.671 95.711  1.00 43.89 ? 143 LEU A N   1 
ATOM   942   C CA  . LEU A 1 143 ? 121.931 111.394 96.180  1.00 43.89 ? 143 LEU A CA  1 
ATOM   943   C C   . LEU A 1 143 ? 122.927 112.377 95.583  1.00 43.89 ? 143 LEU A C   1 
ATOM   944   O O   . LEU A 1 143 ? 123.774 112.924 96.294  1.00 43.89 ? 143 LEU A O   1 
ATOM   945   C CB  . LEU A 1 143 ? 122.306 109.957 95.835  1.00 43.89 ? 143 LEU A CB  1 
ATOM   946   C CG  . LEU A 1 143 ? 123.734 109.507 96.095  1.00 43.89 ? 143 LEU A CG  1 
ATOM   947   C CD1 . LEU A 1 143 ? 124.056 109.642 97.546  1.00 43.89 ? 143 LEU A CD1 1 
ATOM   948   C CD2 . LEU A 1 143 ? 123.897 108.080 95.669  1.00 43.89 ? 143 LEU A CD2 1 
ATOM   949   N N   . MET A 1 144 ? 122.829 112.627 94.274  1.00 48.55 ? 144 MET A N   1 
ATOM   950   C CA  . MET A 1 144 ? 123.732 113.572 93.619  1.00 48.55 ? 144 MET A CA  1 
ATOM   951   C C   . MET A 1 144 ? 123.601 114.965 94.215  1.00 48.55 ? 144 MET A C   1 
ATOM   952   O O   . MET A 1 144 ? 124.600 115.632 94.500  1.00 48.55 ? 144 MET A O   1 
ATOM   953   C CB  . MET A 1 144 ? 123.439 113.623 92.122  1.00 48.55 ? 144 MET A CB  1 
ATOM   954   C CG  . MET A 1 144 ? 123.855 112.403 91.344  1.00 48.55 ? 144 MET A CG  1 
ATOM   955   S SD  . MET A 1 144 ? 123.993 112.748 89.582  1.00 48.55 ? 144 MET A SD  1 
ATOM   956   C CE  . MET A 1 144 ? 125.214 114.052 89.580  1.00 48.55 ? 144 MET A CE  1 
ATOM   957   N N   . GLN A 1 145 ? 122.366 115.420 94.400  1.00 46.67 ? 145 GLN A N   1 
ATOM   958   C CA  . GLN A 1 145 ? 122.112 116.756 94.919  1.00 46.67 ? 145 GLN A CA  1 
ATOM   959   C C   . GLN A 1 145 ? 122.610 116.903 96.346  1.00 46.67 ? 145 GLN A C   1 
ATOM   960   O O   . GLN A 1 145 ? 123.293 117.874 96.677  1.00 46.67 ? 145 GLN A O   1 
ATOM   961   C CB  . GLN A 1 145 ? 120.623 117.050 94.842  1.00 46.67 ? 145 GLN A CB  1 
ATOM   962   C CG  . GLN A 1 145 ? 120.197 118.218 95.663  1.00 46.67 ? 145 GLN A CG  1 
ATOM   963   C CD  . GLN A 1 145 ? 118.759 118.564 95.431  1.00 46.67 ? 145 GLN A CD  1 
ATOM   964   O OE1 . GLN A 1 145 ? 118.119 118.014 94.542  1.00 46.67 ? 145 GLN A OE1 1 
ATOM   965   N NE2 . GLN A 1 145 ? 118.229 119.470 96.240  1.00 46.67 ? 145 GLN A NE2 1 
ATOM   966   N N   . ARG A 1 146 ? 122.237 115.968 97.215  1.00 48.47 ? 146 ARG A N   1 
ATOM   967   C CA  . ARG A 1 146 ? 122.728 115.981 98.582  1.00 48.47 ? 146 ARG A CA  1 
ATOM   968   C C   . ARG A 1 146 ? 124.243 115.979 98.613  1.00 48.47 ? 146 ARG A C   1 
ATOM   969   O O   . ARG A 1 146 ? 124.859 116.729 99.373  1.00 48.47 ? 146 ARG A O   1 
ATOM   970   C CB  . ARG A 1 146 ? 122.169 114.772 99.323  1.00 48.47 ? 146 ARG A CB  1 
ATOM   971   C CG  . ARG A 1 146 ? 122.411 114.766 100.798 1.00 48.47 ? 146 ARG A CG  1 
ATOM   972   C CD  . ARG A 1 146 ? 121.586 115.816 101.480 1.00 48.47 ? 146 ARG A CD  1 
ATOM   973   N NE  . ARG A 1 146 ? 122.424 116.908 101.951 1.00 48.47 ? 146 ARG A NE  1 
ATOM   974   C CZ  . ARG A 1 146 ? 121.977 117.943 102.648 1.00 48.47 ? 146 ARG A CZ  1 
ATOM   975   N NH1 . ARG A 1 146 ? 120.694 118.028 102.963 1.00 48.47 ? 146 ARG A NH1 1 
ATOM   976   N NH2 . ARG A 1 146 ? 122.817 118.891 103.031 1.00 48.47 ? 146 ARG A NH2 1 
ATOM   977   N N   . LEU A 1 147 ? 124.862 115.164 97.770  1.00 47.13 ? 147 LEU A N   1 
ATOM   978   C CA  . LEU A 1 147 ? 126.305 115.042 97.800  1.00 47.13 ? 147 LEU A CA  1 
ATOM   979   C C   . LEU A 1 147 ? 126.977 116.314 97.299  1.00 47.13 ? 147 LEU A C   1 
ATOM   980   O O   . LEU A 1 147 ? 128.072 116.657 97.753  1.00 47.13 ? 147 LEU A O   1 
ATOM   981   C CB  . LEU A 1 147 ? 126.710 113.833 96.968  1.00 47.13 ? 147 LEU A CB  1 
ATOM   982   C CG  . LEU A 1 147 ? 128.100 113.278 97.205  1.00 47.13 ? 147 LEU A CG  1 
ATOM   983   C CD1 . LEU A 1 147 ? 128.136 112.739 98.600  1.00 47.13 ? 147 LEU A CD1 1 
ATOM   984   C CD2 . LEU A 1 147 ? 128.376 112.185 96.220  1.00 47.13 ? 147 LEU A CD2 1 
ATOM   985   N N   . GLY A 1 148 ? 126.341 117.030 96.374  1.00 51.68 ? 148 GLY A N   1 
ATOM   986   C CA  . GLY A 1 148 ? 126.883 118.312 95.952  1.00 51.68 ? 148 GLY A CA  1 
ATOM   987   C C   . GLY A 1 148 ? 126.669 119.401 96.985  1.00 51.68 ? 148 GLY A C   1 
ATOM   988   O O   . GLY A 1 148 ? 127.519 120.274 97.165  1.00 51.68 ? 148 GLY A O   1 
ATOM   989   N N   . GLN A 1 149 ? 125.528 119.370 97.668  1.00 49.44 ? 149 GLN A N   1 
ATOM   990   C CA  . GLN A 1 149 ? 125.277 120.314 98.749  1.00 49.44 ? 149 GLN A CA  1 
ATOM   991   C C   . GLN A 1 149 ? 126.282 120.140 99.876  1.00 49.44 ? 149 GLN A C   1 
ATOM   992   O O   . GLN A 1 149 ? 126.708 121.120 100.493 1.00 49.44 ? 149 GLN A O   1 
ATOM   993   C CB  . GLN A 1 149 ? 123.857 120.131 99.270  1.00 49.44 ? 149 GLN A CB  1 
ATOM   994   C CG  . GLN A 1 149 ? 123.562 120.876 100.541 1.00 49.44 ? 149 GLN A CG  1 
ATOM   995   C CD  . GLN A 1 149 ? 123.187 122.316 100.294 1.00 49.44 ? 149 GLN A CD  1 
ATOM   996   O OE1 . GLN A 1 149 ? 122.876 122.703 99.171  1.00 49.44 ? 149 GLN A OE1 1 
ATOM   997   N NE2 . GLN A 1 149 ? 123.209 123.120 101.348 1.00 49.44 ? 149 GLN A NE2 1 
ATOM   998   N N   . LEU A 1 150 ? 126.676 118.900 100.161 1.00 49.51 ? 150 LEU A N   1 
ATOM   999   C CA  . LEU A 1 150 ? 127.677 118.680 101.198 1.00 49.51 ? 150 LEU A CA  1 
ATOM   1000  C C   . LEU A 1 150 ? 129.019 119.263 100.791 1.00 49.51 ? 150 LEU A C   1 
ATOM   1001  O O   . LEU A 1 150 ? 129.646 119.993 101.564 1.00 49.51 ? 150 LEU A O   1 
ATOM   1002  C CB  . LEU A 1 150 ? 127.808 117.190 101.503 1.00 49.51 ? 150 LEU A CB  1 
ATOM   1003  C CG  . LEU A 1 150 ? 126.557 116.537 102.089 1.00 49.51 ? 150 LEU A CG  1 
ATOM   1004  C CD1 . LEU A 1 150 ? 126.838 115.126 102.563 1.00 49.51 ? 150 LEU A CD1 1 
ATOM   1005  C CD2 . LEU A 1 150 ? 125.995 117.384 103.214 1.00 49.51 ? 150 LEU A CD2 1 
ATOM   1006  N N   . GLN A 1 151 ? 129.480 118.955 99.580  1.00 54.26 ? 151 GLN A N   1 
ATOM   1007  C CA  . GLN A 1 151 ? 130.746 119.471 99.061  1.00 54.26 ? 151 GLN A CA  1 
ATOM   1008  C C   . GLN A 1 151 ? 130.460 120.295 97.815  1.00 54.26 ? 151 GLN A C   1 
ATOM   1009  O O   . GLN A 1 151 ? 130.459 119.758 96.699  1.00 54.26 ? 151 GLN A O   1 
ATOM   1010  C CB  . GLN A 1 151 ? 131.717 118.339 98.737  1.00 54.26 ? 151 GLN A CB  1 
ATOM   1011  C CG  . GLN A 1 151 ? 131.860 117.287 99.820  1.00 54.26 ? 151 GLN A CG  1 
ATOM   1012  C CD  . GLN A 1 151 ? 131.108 116.017 99.492  1.00 54.26 ? 151 GLN A CD  1 
ATOM   1013  O OE1 . GLN A 1 151 ? 130.612 115.853 98.382  1.00 54.26 ? 151 GLN A OE1 1 
ATOM   1014  N NE2 . GLN A 1 151 ? 131.033 115.105 100.451 1.00 54.26 ? 151 GLN A NE2 1 
ATOM   1015  N N   . PRO A 1 152 ? 130.207 121.595 97.951  1.00 57.34 ? 152 PRO A N   1 
ATOM   1016  C CA  . PRO A 1 152 ? 129.898 122.405 96.768  1.00 57.34 ? 152 PRO A CA  1 
ATOM   1017  C C   . PRO A 1 152 ? 131.080 122.469 95.817  1.00 57.34 ? 152 PRO A C   1 
ATOM   1018  O O   . PRO A 1 152 ? 132.240 122.464 96.235  1.00 57.34 ? 152 PRO A O   1 
ATOM   1019  C CB  . PRO A 1 152 ? 129.573 123.781 97.355  1.00 57.34 ? 152 PRO A CB  1 
ATOM   1020  C CG  . PRO A 1 152 ? 129.183 123.503 98.761  1.00 57.34 ? 152 PRO A CG  1 
ATOM   1021  C CD  . PRO A 1 152 ? 130.051 122.365 99.192  1.00 57.34 ? 152 PRO A CD  1 
ATOM   1022  N N   . GLY A 1 153 ? 130.772 122.513 94.525  1.00 57.79 ? 153 GLY A N   1 
ATOM   1023  C CA  . GLY A 1 153 ? 131.789 122.508 93.499  1.00 57.79 ? 153 GLY A CA  1 
ATOM   1024  C C   . GLY A 1 153 ? 132.450 121.172 93.257  1.00 57.79 ? 153 GLY A C   1 
ATOM   1025  O O   . GLY A 1 153 ? 133.349 121.088 92.412  1.00 57.79 ? 153 GLY A O   1 
ATOM   1026  N N   . GLY A 1 154 ? 132.035 120.125 93.960  1.00 61.03 ? 154 GLY A N   1 
ATOM   1027  C CA  . GLY A 1 154 ? 132.644 118.823 93.842  1.00 61.03 ? 154 GLY A CA  1 
ATOM   1028  C C   . GLY A 1 154 ? 131.925 117.829 92.964  1.00 61.03 ? 154 GLY A C   1 
ATOM   1029  O O   . GLY A 1 154 ? 132.364 116.681 92.876  1.00 61.03 ? 154 GLY A O   1 
ATOM   1030  N N   . VAL A 1 155 ? 130.830 118.219 92.316  1.00 59.86 ? 155 VAL A N   1 
ATOM   1031  C CA  . VAL A 1 155 ? 130.048 117.316 91.469  1.00 59.86 ? 155 VAL A CA  1 
ATOM   1032  C C   . VAL A 1 155 ? 129.772 118.042 90.166  1.00 59.86 ? 155 VAL A C   1 
ATOM   1033  O O   . VAL A 1 155 ? 128.806 118.805 90.045  1.00 59.86 ? 155 VAL A O   1 
ATOM   1034  C CB  . VAL A 1 155 ? 128.744 116.869 92.141  1.00 59.86 ? 155 VAL A CB  1 
ATOM   1035  C CG1 . VAL A 1 155 ? 127.955 115.986 91.206  1.00 59.86 ? 155 VAL A CG1 1 
ATOM   1036  C CG2 . VAL A 1 155 ? 129.042 116.139 93.426  1.00 59.86 ? 155 VAL A CG2 1 
ATOM   1037  N N   . ASP A 1 156 ? 130.614 117.810 89.160  1.00 60.86 ? 156 ASP A N   1 
ATOM   1038  C CA  . ASP A 1 156 ? 130.376 118.355 87.834  1.00 60.86 ? 156 ASP A CA  1 
ATOM   1039  C C   . ASP A 1 156 ? 129.393 117.470 87.085  1.00 60.86 ? 156 ASP A C   1 
ATOM   1040  O O   . ASP A 1 156 ? 129.519 116.245 87.078  1.00 60.86 ? 156 ASP A O   1 
ATOM   1041  C CB  . ASP A 1 156 ? 131.686 118.472 87.060  1.00 60.86 ? 156 ASP A CB  1 
ATOM   1042  C CG  . ASP A 1 156 ? 131.520 119.167 85.726  1.00 60.86 ? 156 ASP A CG  1 
ATOM   1043  O OD1 . ASP A 1 156 ? 130.406 119.638 85.431  1.00 60.86 ? 156 ASP A OD1 1 
ATOM   1044  O OD2 . ASP A 1 156 ? 132.507 119.246 84.969  1.00 60.86 ? 156 ASP A OD2 1 
ATOM   1045  N N   . SER A 1 157 ? 128.418 118.100 86.437  1.00 56.12 ? 157 SER A N   1 
ATOM   1046  C CA  . SER A 1 157 ? 127.274 117.393 85.884  1.00 56.12 ? 157 SER A CA  1 
ATOM   1047  C C   . SER A 1 157 ? 127.251 117.389 84.362  1.00 56.12 ? 157 SER A C   1 
ATOM   1048  O O   . SER A 1 157 ? 126.190 117.195 83.770  1.00 56.12 ? 157 SER A O   1 
ATOM   1049  C CB  . SER A 1 157 ? 125.984 118.004 86.425  1.00 56.12 ? 157 SER A CB  1 
ATOM   1050  O OG  . SER A 1 157 ? 124.860 117.233 86.052  1.00 56.12 ? 157 SER A OG  1 
ATOM   1051  N N   . THR A 1 158 ? 128.394 117.587 83.711  1.00 57.54 ? 158 THR A N   1 
ATOM   1052  C CA  . THR A 1 158 ? 128.407 117.658 82.255  1.00 57.54 ? 158 THR A CA  1 
ATOM   1053  C C   . THR A 1 158 ? 127.996 116.333 81.624  1.00 57.54 ? 158 THR A C   1 
ATOM   1054  O O   . THR A 1 158 ? 126.964 116.241 80.947  1.00 57.54 ? 158 THR A O   1 
ATOM   1055  C CB  . THR A 1 158 ? 129.790 118.066 81.767  1.00 57.54 ? 158 THR A CB  1 
ATOM   1056  O OG1 . THR A 1 158 ? 130.137 119.331 82.337  1.00 57.54 ? 158 THR A OG1 1 
ATOM   1057  C CG2 . THR A 1 158 ? 129.785 118.184 80.273  1.00 57.54 ? 158 THR A CG2 1 
ATOM   1058  N N   . MET A 1 159 ? 128.795 115.289 81.837  1.00 58.78 ? 159 MET A N   1 
ATOM   1059  C CA  . MET A 1 159 ? 128.555 114.032 81.141  1.00 58.78 ? 159 MET A CA  1 
ATOM   1060  C C   . MET A 1 159 ? 127.236 113.417 81.558  1.00 58.78 ? 159 MET A C   1 
ATOM   1061  O O   . MET A 1 159 ? 126.578 112.748 80.757  1.00 58.78 ? 159 MET A O   1 
ATOM   1062  C CB  . MET A 1 159 ? 129.689 113.052 81.403  1.00 58.78 ? 159 MET A CB  1 
ATOM   1063  C CG  . MET A 1 159 ? 131.056 113.644 81.254  1.00 58.78 ? 159 MET A CG  1 
ATOM   1064  S SD  . MET A 1 159 ? 132.266 112.332 81.249  1.00 58.78 ? 159 MET A SD  1 
ATOM   1065  C CE  . MET A 1 159 ? 131.954 111.639 79.640  1.00 58.78 ? 159 MET A CE  1 
ATOM   1066  N N   . PHE A 1 160 ? 126.848 113.605 82.816  1.00 51.29 ? 160 PHE A N   1 
ATOM   1067  C CA  . PHE A 1 160 ? 125.513 113.198 83.220  1.00 51.29 ? 160 PHE A CA  1 
ATOM   1068  C C   . PHE A 1 160 ? 124.477 113.879 82.351  1.00 51.29 ? 160 PHE A C   1 
ATOM   1069  O O   . PHE A 1 160 ? 123.538 113.237 81.869  1.00 51.29 ? 160 PHE A O   1 
ATOM   1070  C CB  . PHE A 1 160 ? 125.279 113.524 84.694  1.00 51.29 ? 160 PHE A CB  1 
ATOM   1071  C CG  . PHE A 1 160 ? 123.993 112.976 85.237  1.00 51.29 ? 160 PHE A CG  1 
ATOM   1072  C CD1 . PHE A 1 160 ? 122.793 113.605 84.986  1.00 51.29 ? 160 PHE A CD1 1 
ATOM   1073  C CD2 . PHE A 1 160 ? 123.984 111.831 85.998  1.00 51.29 ? 160 PHE A CD2 1 
ATOM   1074  C CE1 . PHE A 1 160 ? 121.619 113.102 85.476  1.00 51.29 ? 160 PHE A CE1 1 
ATOM   1075  C CE2 . PHE A 1 160 ? 122.806 111.327 86.492  1.00 51.29 ? 160 PHE A CE2 1 
ATOM   1076  C CZ  . PHE A 1 160 ? 121.625 111.963 86.229  1.00 51.29 ? 160 PHE A CZ  1 
ATOM   1077  N N   . ASP A 1 161 ? 124.651 115.178 82.114  1.00 57.14 ? 161 ASP A N   1 
ATOM   1078  C CA  . ASP A 1 161 ? 123.694 115.914 81.304  1.00 57.14 ? 161 ASP A CA  1 
ATOM   1079  C C   . ASP A 1 161 ? 123.655 115.380 79.884  1.00 57.14 ? 161 ASP A C   1 
ATOM   1080  O O   . ASP A 1 161 ? 122.585 115.293 79.276  1.00 57.14 ? 161 ASP A O   1 
ATOM   1081  C CB  . ASP A 1 161 ? 124.041 117.398 81.307  1.00 57.14 ? 161 ASP A CB  1 
ATOM   1082  C CG  . ASP A 1 161 ? 123.771 118.058 82.640  1.00 57.14 ? 161 ASP A CG  1 
ATOM   1083  O OD1 . ASP A 1 161 ? 123.026 117.482 83.456  1.00 57.14 ? 161 ASP A OD1 1 
ATOM   1084  O OD2 . ASP A 1 161 ? 124.318 119.153 82.877  1.00 57.14 ? 161 ASP A OD2 1 
ATOM   1085  N N   . HIS A 1 162 ? 124.811 115.001 79.342  1.00 57.43 ? 162 HIS A N   1 
ATOM   1086  C CA  . HIS A 1 162 ? 124.830 114.542 77.958  1.00 57.43 ? 162 HIS A CA  1 
ATOM   1087  C C   . HIS A 1 162 ? 124.234 113.150 77.812  1.00 57.43 ? 162 HIS A C   1 
ATOM   1088  O O   . HIS A 1 162 ? 123.550 112.870 76.824  1.00 57.43 ? 162 HIS A O   1 
ATOM   1089  C CB  . HIS A 1 162 ? 126.244 114.550 77.396  1.00 57.43 ? 162 HIS A CB  1 
ATOM   1090  C CG  . HIS A 1 162 ? 126.309 114.082 75.978  1.00 57.43 ? 162 HIS A CG  1 
ATOM   1091  N ND1 . HIS A 1 162 ? 126.217 114.943 74.908  1.00 57.43 ? 162 HIS A ND1 1 
ATOM   1092  C CD2 . HIS A 1 162 ? 126.412 112.840 75.453  1.00 57.43 ? 162 HIS A CD2 1 
ATOM   1093  C CE1 . HIS A 1 162 ? 126.279 114.253 73.785  1.00 57.43 ? 162 HIS A CE1 1 
ATOM   1094  N NE2 . HIS A 1 162 ? 126.397 112.975 74.088  1.00 57.43 ? 162 HIS A NE2 1 
ATOM   1095  N N   . PHE A 1 163 ? 124.496 112.259 78.767  1.00 54.08 ? 163 PHE A N   1 
ATOM   1096  C CA  . PHE A 1 163 ? 124.161 110.851 78.596  1.00 54.08 ? 163 PHE A CA  1 
ATOM   1097  C C   . PHE A 1 163 ? 122.825 110.454 79.189  1.00 54.08 ? 163 PHE A C   1 
ATOM   1098  O O   . PHE A 1 163 ? 122.241 109.471 78.731  1.00 54.08 ? 163 PHE A O   1 
ATOM   1099  C CB  . PHE A 1 163 ? 125.239 109.969 79.213  1.00 54.08 ? 163 PHE A CB  1 
ATOM   1100  C CG  . PHE A 1 163 ? 126.441 109.823 78.361  1.00 54.08 ? 163 PHE A CG  1 
ATOM   1101  C CD1 . PHE A 1 163 ? 126.391 109.087 77.203  1.00 54.08 ? 163 PHE A CD1 1 
ATOM   1102  C CD2 . PHE A 1 163 ? 127.624 110.427 78.712  1.00 54.08 ? 163 PHE A CD2 1 
ATOM   1103  C CE1 . PHE A 1 163 ? 127.499 108.955 76.414  1.00 54.08 ? 163 PHE A CE1 1 
ATOM   1104  C CE2 . PHE A 1 163 ? 128.735 110.295 77.923  1.00 54.08 ? 163 PHE A CE2 1 
ATOM   1105  C CZ  . PHE A 1 163 ? 128.671 109.560 76.773  1.00 54.08 ? 163 PHE A CZ  1 
ATOM   1106  N N   . TYR A 1 164 ? 122.333 111.160 80.198  1.00 52.09 ? 164 TYR A N   1 
ATOM   1107  C CA  . TYR A 1 164 ? 120.998 110.871 80.701  1.00 52.09 ? 164 TYR A CA  1 
ATOM   1108  C C   . TYR A 1 164 ? 119.936 110.837 79.610  1.00 52.09 ? 164 TYR A C   1 
ATOM   1109  O O   . TYR A 1 164 ? 119.000 110.030 79.730  1.00 52.09 ? 164 TYR A O   1 
ATOM   1110  C CB  . TYR A 1 164 ? 120.632 111.893 81.786  1.00 52.09 ? 164 TYR A CB  1 
ATOM   1111  C CG  . TYR A 1 164 ? 119.337 111.597 82.498  1.00 52.09 ? 164 TYR A CG  1 
ATOM   1112  C CD1 . TYR A 1 164 ? 119.294 110.710 83.554  1.00 52.09 ? 164 TYR A CD1 1 
ATOM   1113  C CD2 . TYR A 1 164 ? 118.160 112.209 82.115  1.00 52.09 ? 164 TYR A CD2 1 
ATOM   1114  C CE1 . TYR A 1 164 ? 118.115 110.436 84.204  1.00 52.09 ? 164 TYR A CE1 1 
ATOM   1115  C CE2 . TYR A 1 164 ? 116.980 111.943 82.762  1.00 52.09 ? 164 TYR A CE2 1 
ATOM   1116  C CZ  . TYR A 1 164 ? 116.963 111.055 83.805  1.00 52.09 ? 164 TYR A CZ  1 
ATOM   1117  O OH  . TYR A 1 164 ? 115.785 110.784 84.456  1.00 52.09 ? 164 TYR A OH  1 
ATOM   1118  N N   . PRO A 1 165 ? 119.991 111.655 78.554  1.00 52.24 ? 165 PRO A N   1 
ATOM   1119  C CA  . PRO A 1 165 ? 118.980 111.508 77.498  1.00 52.24 ? 165 PRO A CA  1 
ATOM   1120  C C   . PRO A 1 165 ? 119.165 110.271 76.639  1.00 52.24 ? 165 PRO A C   1 
ATOM   1121  O O   . PRO A 1 165 ? 118.180 109.608 76.296  1.00 52.24 ? 165 PRO A O   1 
ATOM   1122  C CB  . PRO A 1 165 ? 119.152 112.791 76.679  1.00 52.24 ? 165 PRO A CB  1 
ATOM   1123  C CG  . PRO A 1 165 ? 119.838 113.725 77.571  1.00 52.24 ? 165 PRO A CG  1 
ATOM   1124  C CD  . PRO A 1 165 ? 120.742 112.909 78.391  1.00 52.24 ? 165 PRO A CD  1 
ATOM   1125  N N   . LEU A 1 166 ? 120.401 109.937 76.282  1.00 53.78 ? 166 LEU A N   1 
ATOM   1126  C CA  . LEU A 1 166 ? 120.636 108.902 75.285  1.00 53.78 ? 166 LEU A CA  1 
ATOM   1127  C C   . LEU A 1 166 ? 120.588 107.507 75.888  1.00 53.78 ? 166 LEU A C   1 
ATOM   1128  O O   . LEU A 1 166 ? 119.987 106.598 75.310  1.00 53.78 ? 166 LEU A O   1 
ATOM   1129  C CB  . LEU A 1 166 ? 121.977 109.146 74.606  1.00 53.78 ? 166 LEU A CB  1 
ATOM   1130  C CG  . LEU A 1 166 ? 122.169 110.611 74.237  1.00 53.78 ? 166 LEU A CG  1 
ATOM   1131  C CD1 . LEU A 1 166 ? 123.551 110.862 73.694  1.00 53.78 ? 166 LEU A CD1 1 
ATOM   1132  C CD2 . LEU A 1 166 ? 121.120 111.012 73.230  1.00 53.78 ? 166 LEU A CD2 1 
ATOM   1133  N N   . LEU A 1 167 ? 121.218 107.314 77.043  1.00 56.04 ? 167 LEU A N   1 
ATOM   1134  C CA  . LEU A 1 167 ? 121.295 105.993 77.652  1.00 56.04 ? 167 LEU A CA  1 
ATOM   1135  C C   . LEU A 1 167 ? 120.151 105.711 78.610  1.00 56.04 ? 167 LEU A C   1 
ATOM   1136  O O   . LEU A 1 167 ? 119.466 104.698 78.472  1.00 56.04 ? 167 LEU A O   1 
ATOM   1137  C CB  . LEU A 1 167 ? 122.609 105.837 78.408  1.00 56.04 ? 167 LEU A CB  1 
ATOM   1138  C CG  . LEU A 1 167 ? 123.892 105.925 77.600  1.00 56.04 ? 167 LEU A CG  1 
ATOM   1139  C CD1 . LEU A 1 167 ? 125.057 105.958 78.550  1.00 56.04 ? 167 LEU A CD1 1 
ATOM   1140  C CD2 . LEU A 1 167 ? 124.001 104.752 76.661  1.00 56.04 ? 167 LEU A CD2 1 
ATOM   1141  N N   . CYS A 1 168 ? 119.940 106.578 79.588  1.00 56.07 ? 168 CYS A N   1 
ATOM   1142  C CA  . CYS A 1 168 ? 118.999 106.295 80.652  1.00 56.07 ? 168 CYS A CA  1 
ATOM   1143  C C   . CYS A 1 168 ? 117.575 106.527 80.174  1.00 56.07 ? 168 CYS A C   1 
ATOM   1144  O O   . CYS A 1 168 ? 117.325 106.912 79.033  1.00 56.07 ? 168 CYS A O   1 
ATOM   1145  C CB  . CYS A 1 168 ? 119.306 107.150 81.875  1.00 56.07 ? 168 CYS A CB  1 
ATOM   1146  S SG  . CYS A 1 168 ? 118.223 106.843 83.274  1.00 56.07 ? 168 CYS A SG  1 
ATOM   1147  N N   . VAL A 1 169 ? 116.626 106.279 81.065  1.00 58.69 ? 169 VAL A N   1 
ATOM   1148  C CA  . VAL A 1 169 ? 115.220 106.535 80.810  1.00 58.69 ? 169 VAL A CA  1 
ATOM   1149  C C   . VAL A 1 169 ? 114.642 107.233 82.026  1.00 58.69 ? 169 VAL A C   1 
ATOM   1150  O O   . VAL A 1 169 ? 114.752 106.727 83.146  1.00 58.69 ? 169 VAL A O   1 
ATOM   1151  C CB  . VAL A 1 169 ? 114.443 105.243 80.518  1.00 58.69 ? 169 VAL A CB  1 
ATOM   1152  C CG1 . VAL A 1 169 ? 112.968 105.515 80.575  1.00 58.69 ? 169 VAL A CG1 1 
ATOM   1153  C CG2 . VAL A 1 169 ? 114.817 104.707 79.161  1.00 58.69 ? 169 VAL A CG2 1 
ATOM   1154  N N   . ASP A 1 170 ? 114.032 108.391 81.808  1.00 61.51 ? 170 ASP A N   1 
ATOM   1155  C CA  . ASP A 1 170 ? 113.429 109.142 82.892  1.00 61.51 ? 170 ASP A CA  1 
ATOM   1156  C C   . ASP A 1 170 ? 112.156 108.453 83.361  1.00 61.51 ? 170 ASP A C   1 
ATOM   1157  O O   . ASP A 1 170 ? 111.719 107.443 82.808  1.00 61.51 ? 170 ASP A O   1 
ATOM   1158  C CB  . ASP A 1 170 ? 113.138 110.570 82.449  1.00 61.51 ? 170 ASP A CB  1 
ATOM   1159  C CG  . ASP A 1 170 ? 112.546 110.625 81.063  1.00 61.51 ? 170 ASP A CG  1 
ATOM   1160  O OD1 . ASP A 1 170 ? 112.652 109.608 80.354  1.00 61.51 ? 170 ASP A OD1 1 
ATOM   1161  O OD2 . ASP A 1 170 ? 111.969 111.667 80.686  1.00 61.51 ? 170 ASP A OD2 1 
ATOM   1162  N N   . GLY A 1 171 ? 111.553 109.013 84.397  1.00 59.22 ? 171 GLY A N   1 
ATOM   1163  C CA  . GLY A 1 171 ? 110.315 108.508 84.930  1.00 59.22 ? 171 GLY A CA  1 
ATOM   1164  C C   . GLY A 1 171 ? 109.190 108.460 83.920  1.00 59.22 ? 171 GLY A C   1 
ATOM   1165  O O   . GLY A 1 171 ? 108.585 107.408 83.698  1.00 59.22 ? 171 GLY A O   1 
ATOM   1166  N N   . PRO A 1 172 ? 108.876 109.598 83.292  1.00 60.15 ? 172 PRO A N   1 
ATOM   1167  C CA  . PRO A 1 172 ? 107.714 109.616 82.389  1.00 60.15 ? 172 PRO A CA  1 
ATOM   1168  C C   . PRO A 1 172 ? 107.865 108.718 81.177  1.00 60.15 ? 172 PRO A C   1 
ATOM   1169  O O   . PRO A 1 172 ? 106.909 108.031 80.803  1.00 60.15 ? 172 PRO A O   1 
ATOM   1170  C CB  . PRO A 1 172 ? 107.611 111.094 81.998  1.00 60.15 ? 172 PRO A CB  1 
ATOM   1171  C CG  . PRO A 1 172 ? 108.250 111.812 83.111  1.00 60.15 ? 172 PRO A CG  1 
ATOM   1172  C CD  . PRO A 1 172 ? 109.394 110.956 83.520  1.00 60.15 ? 172 PRO A CD  1 
ATOM   1173  N N   . GLU A 1 173 ? 109.036 108.704 80.544  1.00 62.46 ? 173 GLU A N   1 
ATOM   1174  C CA  . GLU A 1 173 ? 109.233 107.830 79.395  1.00 62.46 ? 173 GLU A CA  1 
ATOM   1175  C C   . GLU A 1 173 ? 109.063 106.372 79.780  1.00 62.46 ? 173 GLU A C   1 
ATOM   1176  O O   . GLU A 1 173 ? 108.424 105.601 79.057  1.00 62.46 ? 173 GLU A O   1 
ATOM   1177  C CB  . GLU A 1 173 ? 110.615 108.064 78.800  1.00 62.46 ? 173 GLU A CB  1 
ATOM   1178  C CG  . GLU A 1 173 ? 110.942 107.217 77.603  1.00 62.46 ? 173 GLU A CG  1 
ATOM   1179  C CD  . GLU A 1 173 ? 112.271 107.600 77.002  1.00 62.46 ? 173 GLU A CD  1 
ATOM   1180  O OE1 . GLU A 1 173 ? 113.050 108.289 77.692  1.00 62.46 ? 173 GLU A OE1 1 
ATOM   1181  O OE2 . GLU A 1 173 ? 112.537 107.221 75.844  1.00 62.46 ? 173 GLU A OE2 1 
ATOM   1182  N N   . ALA A 1 174 ? 109.626 105.975 80.921  1.00 59.48 ? 174 ALA A N   1 
ATOM   1183  C CA  . ALA A 1 174 ? 109.470 104.603 81.378  1.00 59.48 ? 174 ALA A CA  1 
ATOM   1184  C C   . ALA A 1 174 ? 108.023 104.288 81.709  1.00 59.48 ? 174 ALA A C   1 
ATOM   1185  O O   . ALA A 1 174 ? 107.578 103.153 81.520  1.00 59.48 ? 174 ALA A O   1 
ATOM   1186  C CB  . ALA A 1 174 ? 110.355 104.349 82.593  1.00 59.48 ? 174 ALA A CB  1 
ATOM   1187  N N   . ARG A 1 175 ? 107.271 105.269 82.198  1.00 58.53 ? 175 ARG A N   1 
ATOM   1188  C CA  . ARG A 1 175 ? 105.885 105.002 82.547  1.00 58.53 ? 175 ARG A CA  1 
ATOM   1189  C C   . ARG A 1 175 ? 104.988 104.920 81.322  1.00 58.53 ? 175 ARG A C   1 
ATOM   1190  O O   . ARG A 1 175 ? 104.011 104.165 81.331  1.00 58.53 ? 175 ARG A O   1 
ATOM   1191  C CB  . ARG A 1 175 ? 105.369 106.067 83.508  1.00 58.53 ? 175 ARG A CB  1 
ATOM   1192  C CG  . ARG A 1 175 ? 105.928 105.939 84.908  1.00 58.53 ? 175 ARG A CG  1 
ATOM   1193  C CD  . ARG A 1 175 ? 105.044 106.619 85.932  1.00 58.53 ? 175 ARG A CD  1 
ATOM   1194  N NE  . ARG A 1 175 ? 105.059 108.071 85.797  1.00 58.53 ? 175 ARG A NE  1 
ATOM   1195  C CZ  . ARG A 1 175 ? 106.066 108.853 86.171  1.00 58.53 ? 175 ARG A CZ  1 
ATOM   1196  N NH1 . ARG A 1 175 ? 107.159 108.330 86.705  1.00 58.53 ? 175 ARG A NH1 1 
ATOM   1197  N NH2 . ARG A 1 175 ? 105.979 110.163 86.008  1.00 58.53 ? 175 ARG A NH2 1 
ATOM   1198  N N   . ARG A 1 176 ? 105.291 105.676 80.265  1.00 64.31 ? 176 ARG A N   1 
ATOM   1199  C CA  . ARG A 1 176 ? 104.468 105.599 79.060  1.00 64.31 ? 176 ARG A CA  1 
ATOM   1200  C C   . ARG A 1 176 ? 104.623 104.250 78.376  1.00 64.31 ? 176 ARG A C   1 
ATOM   1201  O O   . ARG A 1 176 ? 103.650 103.690 77.862  1.00 64.31 ? 176 ARG A O   1 
ATOM   1202  C CB  . ARG A 1 176 ? 104.830 106.722 78.089  1.00 64.31 ? 176 ARG A CB  1 
ATOM   1203  C CG  . ARG A 1 176 ? 104.594 108.120 78.625  1.00 64.31 ? 176 ARG A CG  1 
ATOM   1204  C CD  . ARG A 1 176 ? 104.791 109.179 77.556  1.00 64.31 ? 176 ARG A CD  1 
ATOM   1205  N NE  . ARG A 1 176 ? 105.963 108.929 76.724  1.00 64.31 ? 176 ARG A NE  1 
ATOM   1206  C CZ  . ARG A 1 176 ? 107.127 109.558 76.852  1.00 64.31 ? 176 ARG A CZ  1 
ATOM   1207  N NH1 . ARG A 1 176 ? 107.286 110.481 77.785  1.00 64.31 ? 176 ARG A NH1 1 
ATOM   1208  N NH2 . ARG A 1 176 ? 108.134 109.264 76.044  1.00 64.31 ? 176 ARG A NH2 1 
ATOM   1209  N N   . GLN A 1 177 ? 105.836 103.715 78.364  1.00 65.15 ? 177 GLN A N   1 
ATOM   1210  C CA  . GLN A 1 177 ? 106.168 102.486 77.659  1.00 65.15 ? 177 GLN A CA  1 
ATOM   1211  C C   . GLN A 1 177 ? 106.342 101.312 78.616  1.00 65.15 ? 177 GLN A C   1 
ATOM   1212  O O   . GLN A 1 177 ? 107.258 100.506 78.464  1.00 65.15 ? 177 GLN A O   1 
ATOM   1213  C CB  . GLN A 1 177 ? 107.425 102.681 76.818  1.00 65.15 ? 177 GLN A CB  1 
ATOM   1214  C CG  . GLN A 1 177 ? 107.180 103.459 75.541  1.00 65.15 ? 177 GLN A CG  1 
ATOM   1215  C CD  . GLN A 1 177 ? 108.437 104.089 74.991  1.00 65.15 ? 177 GLN A CD  1 
ATOM   1216  O OE1 . GLN A 1 177 ? 109.451 104.170 75.676  1.00 65.15 ? 177 GLN A OE1 1 
ATOM   1217  N NE2 . GLN A 1 177 ? 108.376 104.545 73.749  1.00 65.15 ? 177 GLN A NE2 1 
ATOM   1218  N N   . TRP A 1 178 ? 105.482 101.215 79.632  1.00 64.17 ? 178 TRP A N   1 
ATOM   1219  C CA  . TRP A 1 178 ? 105.657 100.158 80.622  1.00 64.17 ? 178 TRP A CA  1 
ATOM   1220  C C   . TRP A 1 178 ? 105.419 98.780  80.033  1.00 64.17 ? 178 TRP A C   1 
ATOM   1221  O O   . TRP A 1 178 ? 106.004 97.798  80.502  1.00 64.17 ? 178 TRP A O   1 
ATOM   1222  C CB  . TRP A 1 178 ? 104.729 100.362 81.809  1.00 64.17 ? 178 TRP A CB  1 
ATOM   1223  C CG  . TRP A 1 178 ? 105.111 99.471  82.926  1.00 64.17 ? 178 TRP A CG  1 
ATOM   1224  C CD1 . TRP A 1 178 ? 104.408 98.417  83.410  1.00 64.17 ? 178 TRP A CD1 1 
ATOM   1225  C CD2 . TRP A 1 178 ? 106.319 99.535  83.686  1.00 64.17 ? 178 TRP A CD2 1 
ATOM   1226  N NE1 . TRP A 1 178 ? 105.094 97.827  84.441  1.00 64.17 ? 178 TRP A NE1 1 
ATOM   1227  C CE2 . TRP A 1 178 ? 106.272 98.498  84.629  1.00 64.17 ? 178 TRP A CE2 1 
ATOM   1228  C CE3 . TRP A 1 178 ? 107.430 100.376 83.667  1.00 64.17 ? 178 TRP A CE3 1 
ATOM   1229  C CZ2 . TRP A 1 178 ? 107.294 98.280  85.543  1.00 64.17 ? 178 TRP A CZ2 1 
ATOM   1230  C CZ3 . TRP A 1 178 ? 108.438 100.157 84.574  1.00 64.17 ? 178 TRP A CZ3 1 
ATOM   1231  C CH2 . TRP A 1 178 ? 108.364 99.122  85.499  1.00 64.17 ? 178 TRP A CH2 1 
ATOM   1232  N N   . ASP A 1 179 ? 104.552 98.684  79.030  1.00 67.84 ? 179 ASP A N   1 
ATOM   1233  C CA  . ASP A 1 179 ? 104.330 97.413  78.360  1.00 67.84 ? 179 ASP A CA  1 
ATOM   1234  C C   . ASP A 1 179 ? 105.626 96.821  77.829  1.00 67.84 ? 179 ASP A C   1 
ATOM   1235  O O   . ASP A 1 179 ? 105.755 95.598  77.729  1.00 67.84 ? 179 ASP A O   1 
ATOM   1236  C CB  . ASP A 1 179 ? 103.334 97.619  77.228  1.00 67.84 ? 179 ASP A CB  1 
ATOM   1237  C CG  . ASP A 1 179 ? 103.781 98.698  76.255  1.00 67.84 ? 179 ASP A CG  1 
ATOM   1238  O OD1 . ASP A 1 179 ? 104.853 99.297  76.478  1.00 67.84 ? 179 ASP A OD1 1 
ATOM   1239  O OD2 . ASP A 1 179 ? 103.052 98.957  75.277  1.00 67.84 ? 179 ASP A OD2 1 
ATOM   1240  N N   . SER A 1 180 ? 106.602 97.667  77.506  1.00 64.36 ? 180 SER A N   1 
ATOM   1241  C CA  . SER A 1 180 ? 107.804 97.194  76.833  1.00 64.36 ? 180 SER A CA  1 
ATOM   1242  C C   . SER A 1 180 ? 108.783 96.550  77.803  1.00 64.36 ? 180 SER A C   1 
ATOM   1243  O O   . SER A 1 180 ? 109.388 95.523  77.486  1.00 64.36 ? 180 SER A O   1 
ATOM   1244  C CB  . SER A 1 180 ? 108.468 98.350  76.094  1.00 64.36 ? 180 SER A CB  1 
ATOM   1245  O OG  . SER A 1 180 ? 109.823 98.067  75.827  1.00 64.36 ? 180 SER A OG  1 
ATOM   1246  N N   . ILE A 1 181 ? 108.959 97.133  78.984  1.00 65.41 ? 181 ILE A N   1 
ATOM   1247  C CA  . ILE A 1 181 ? 110.034 96.738  79.884  1.00 65.41 ? 181 ILE A CA  1 
ATOM   1248  C C   . ILE A 1 181 ? 109.518 96.020  81.119  1.00 65.41 ? 181 ILE A C   1 
ATOM   1249  O O   . ILE A 1 181 ? 110.293 95.750  82.039  1.00 65.41 ? 181 ILE A O   1 
ATOM   1250  C CB  . ILE A 1 181 ? 110.887 97.945  80.285  1.00 65.41 ? 181 ILE A CB  1 
ATOM   1251  C CG1 . ILE A 1 181 ? 109.993 99.049  80.845  1.00 65.41 ? 181 ILE A CG1 1 
ATOM   1252  C CG2 . ILE A 1 181 ? 111.663 98.447  79.102  1.00 65.41 ? 181 ILE A CG2 1 
ATOM   1253  C CD1 . ILE A 1 181 ? 110.753 100.196 81.448  1.00 65.41 ? 181 ILE A CD1 1 
ATOM   1254  N N   . ALA A 1 182 ? 108.227 95.700  81.167  1.00 67.04 ? 182 ALA A N   1 
ATOM   1255  C CA  . ALA A 1 182 ? 107.686 95.054  82.355  1.00 67.04 ? 182 ALA A CA  1 
ATOM   1256  C C   . ALA A 1 182 ? 108.261 93.656  82.536  1.00 67.04 ? 182 ALA A C   1 
ATOM   1257  O O   . ALA A 1 182 ? 108.476 93.211  83.668  1.00 67.04 ? 182 ALA A O   1 
ATOM   1258  C CB  . ALA A 1 182 ? 106.163 95.003  82.277  1.00 67.04 ? 182 ALA A CB  1 
ATOM   1259  N N   . HIS A 1 183 ? 108.526 92.952  81.436  1.00 67.28 ? 183 HIS A N   1 
ATOM   1260  C CA  . HIS A 1 183 ? 109.046 91.595  81.534  1.00 67.28 ? 183 HIS A CA  1 
ATOM   1261  C C   . HIS A 1 183 ? 110.460 91.544  82.094  1.00 67.28 ? 183 HIS A C   1 
ATOM   1262  O O   . HIS A 1 183 ? 110.914 90.466  82.486  1.00 67.28 ? 183 HIS A O   1 
ATOM   1263  C CB  . HIS A 1 183 ? 109.029 90.928  80.166  1.00 67.28 ? 183 HIS A CB  1 
ATOM   1264  C CG  . HIS A 1 183 ? 110.109 91.414  79.260  1.00 67.28 ? 183 HIS A CG  1 
ATOM   1265  N ND1 . HIS A 1 183 ? 109.927 92.459  78.383  1.00 67.28 ? 183 HIS A ND1 1 
ATOM   1266  C CD2 . HIS A 1 183 ? 111.393 91.016  79.112  1.00 67.28 ? 183 HIS A CD2 1 
ATOM   1267  C CE1 . HIS A 1 183 ? 111.049 92.677  77.724  1.00 67.28 ? 183 HIS A CE1 1 
ATOM   1268  N NE2 . HIS A 1 183 ? 111.955 91.816  78.149  1.00 67.28 ? 183 HIS A NE2 1 
ATOM   1269  N N   . ILE A 1 184 ? 111.177 92.667  82.122  1.00 62.93 ? 184 ILE A N   1 
ATOM   1270  C CA  . ILE A 1 184 ? 112.531 92.657  82.654  1.00 62.93 ? 184 ILE A CA  1 
ATOM   1271  C C   . ILE A 1 184 ? 112.480 92.413  84.152  1.00 62.93 ? 184 ILE A C   1 
ATOM   1272  O O   . ILE A 1 184 ? 111.607 92.934  84.857  1.00 62.93 ? 184 ILE A O   1 
ATOM   1273  C CB  . ILE A 1 184 ? 113.256 93.971  82.331  1.00 62.93 ? 184 ILE A CB  1 
ATOM   1274  C CG1 . ILE A 1 184 ? 113.374 94.143  80.824  1.00 62.93 ? 184 ILE A CG1 1 
ATOM   1275  C CG2 . ILE A 1 184 ? 114.636 93.988  82.948  1.00 62.93 ? 184 ILE A CG2 1 
ATOM   1276  C CD1 . ILE A 1 184 ? 114.227 95.312  80.427  1.00 62.93 ? 184 ILE A CD1 1 
ATOM   1277  N N   . TYR A 1 185 ? 113.414 91.602  84.646  1.00 59.27 ? 185 TYR A N   1 
ATOM   1278  C CA  . TYR A 1 185 ? 113.446 91.302  86.070  1.00 59.27 ? 185 TYR A CA  1 
ATOM   1279  C C   . TYR A 1 185 ? 114.112 92.420  86.859  1.00 59.27 ? 185 TYR A C   1 
ATOM   1280  O O   . TYR A 1 185 ? 113.534 92.944  87.816  1.00 59.27 ? 185 TYR A O   1 
ATOM   1281  C CB  . TYR A 1 185 ? 114.167 89.983  86.317  1.00 59.27 ? 185 TYR A CB  1 
ATOM   1282  C CG  . TYR A 1 185 ? 114.110 89.567  87.760  1.00 59.27 ? 185 TYR A CG  1 
ATOM   1283  C CD1 . TYR A 1 185 ? 112.893 89.348  88.384  1.00 59.27 ? 185 TYR A CD1 1 
ATOM   1284  C CD2 . TYR A 1 185 ? 115.267 89.411  88.505  1.00 59.27 ? 185 TYR A CD2 1 
ATOM   1285  C CE1 . TYR A 1 185 ? 112.829 88.978  89.701  1.00 59.27 ? 185 TYR A CE1 1 
ATOM   1286  C CE2 . TYR A 1 185 ? 115.212 89.040  89.824  1.00 59.27 ? 185 TYR A CE2 1 
ATOM   1287  C CZ  . TYR A 1 185 ? 113.990 88.824  90.417  1.00 59.27 ? 185 TYR A CZ  1 
ATOM   1288  O OH  . TYR A 1 185 ? 113.928 88.451  91.738  1.00 59.27 ? 185 TYR A OH  1 
ATOM   1289  N N   . HIS A 1 186 ? 115.322 92.798  86.476  1.00 58.01 ? 186 HIS A N   1 
ATOM   1290  C CA  . HIS A 1 186 ? 116.061 93.849  87.159  1.00 58.01 ? 186 HIS A CA  1 
ATOM   1291  C C   . HIS A 1 186 ? 115.982 95.120  86.324  1.00 58.01 ? 186 HIS A C   1 
ATOM   1292  O O   . HIS A 1 186 ? 116.632 95.225  85.281  1.00 58.01 ? 186 HIS A O   1 
ATOM   1293  C CB  . HIS A 1 186 ? 117.505 93.426  87.385  1.00 58.01 ? 186 HIS A CB  1 
ATOM   1294  C CG  . HIS A 1 186 ? 118.219 94.259  88.394  1.00 58.01 ? 186 HIS A CG  1 
ATOM   1295  N ND1 . HIS A 1 186 ? 119.592 94.335  88.457  1.00 58.01 ? 186 HIS A ND1 1 
ATOM   1296  C CD2 . HIS A 1 186 ? 117.750 95.054  89.382  1.00 58.01 ? 186 HIS A CD2 1 
ATOM   1297  C CE1 . HIS A 1 186 ? 119.939 95.141  89.444  1.00 58.01 ? 186 HIS A CE1 1 
ATOM   1298  N NE2 . HIS A 1 186 ? 118.841 95.590  90.021  1.00 58.01 ? 186 HIS A NE2 1 
ATOM   1299  N N   . LYS A 1 187 ? 115.185 96.082  86.782  1.00 57.23 ? 187 LYS A N   1 
ATOM   1300  C CA  . LYS A 1 187 ? 115.024 97.354  86.082  1.00 57.23 ? 187 LYS A CA  1 
ATOM   1301  C C   . LYS A 1 187 ? 115.991 98.398  86.638  1.00 57.23 ? 187 LYS A C   1 
ATOM   1302  O O   . LYS A 1 187 ? 115.611 99.472  87.091  1.00 57.23 ? 187 LYS A O   1 
ATOM   1303  C CB  . LYS A 1 187 ? 113.582 97.827  86.181  1.00 57.23 ? 187 LYS A CB  1 
ATOM   1304  C CG  . LYS A 1 187 ? 112.593 96.733  85.921  1.00 57.23 ? 187 LYS A CG  1 
ATOM   1305  C CD  . LYS A 1 187 ? 111.186 97.255  85.906  1.00 57.23 ? 187 LYS A CD  1 
ATOM   1306  C CE  . LYS A 1 187 ? 110.195 96.149  85.570  1.00 57.23 ? 187 LYS A CE  1 
ATOM   1307  N NZ  . LYS A 1 187 ? 109.666 95.460  86.779  1.00 57.23 ? 187 LYS A NZ  1 
ATOM   1308  N N   . CYS A 1 188 ? 117.269 98.056  86.587  1.00 54.09 ? 188 CYS A N   1 
ATOM   1309  C CA  . CYS A 1 188 ? 118.328 98.937  87.046  1.00 54.09 ? 188 CYS A CA  1 
ATOM   1310  C C   . CYS A 1 188 ? 118.758 99.854  85.912  1.00 54.09 ? 188 CYS A C   1 
ATOM   1311  O O   . CYS A 1 188 ? 119.001 99.392  84.796  1.00 54.09 ? 188 CYS A O   1 
ATOM   1312  C CB  . CYS A 1 188 ? 119.514 98.118  87.542  1.00 54.09 ? 188 CYS A CB  1 
ATOM   1313  S SG  . CYS A 1 188 ? 120.975 99.075  87.875  1.00 54.09 ? 188 CYS A SG  1 
ATOM   1314  N N   . HIS A 1 189 ? 118.848 101.148 86.195  1.00 52.39 ? 189 HIS A N   1 
ATOM   1315  C CA  . HIS A 1 189 ? 119.223 102.121 85.180  1.00 52.39 ? 189 HIS A CA  1 
ATOM   1316  C C   . HIS A 1 189 ? 120.319 103.077 85.605  1.00 52.39 ? 189 HIS A C   1 
ATOM   1317  O O   . HIS A 1 189 ? 120.896 103.738 84.736  1.00 52.39 ? 189 HIS A O   1 
ATOM   1318  C CB  . HIS A 1 189 ? 118.000 102.942 84.739  1.00 52.39 ? 189 HIS A CB  1 
ATOM   1319  C CG  . HIS A 1 189 ? 117.214 103.526 85.870  1.00 52.39 ? 189 HIS A CG  1 
ATOM   1320  N ND1 . HIS A 1 189 ? 117.730 104.470 86.730  1.00 52.39 ? 189 HIS A ND1 1 
ATOM   1321  C CD2 . HIS A 1 189 ? 115.939 103.314 86.270  1.00 52.39 ? 189 HIS A CD2 1 
ATOM   1322  C CE1 . HIS A 1 189 ? 116.811 104.807 87.615  1.00 52.39 ? 189 HIS A CE1 1 
ATOM   1323  N NE2 . HIS A 1 189 ? 115.715 104.119 87.359  1.00 52.39 ? 189 HIS A NE2 1 
ATOM   1324  N N   . THR A 1 190 ? 120.630 103.179 86.891  1.00 50.53 ? 190 THR A N   1 
ATOM   1325  C CA  . THR A 1 190 ? 121.642 104.112 87.365  1.00 50.53 ? 190 THR A CA  1 
ATOM   1326  C C   . THR A 1 190 ? 122.315 103.477 88.566  1.00 50.53 ? 190 THR A C   1 
ATOM   1327  O O   . THR A 1 190 ? 121.636 103.132 89.535  1.00 50.53 ? 190 THR A O   1 
ATOM   1328  C CB  . THR A 1 190 ? 121.019 105.448 87.759  1.00 50.53 ? 190 THR A CB  1 
ATOM   1329  O OG1 . THR A 1 190 ? 120.234 105.958 86.678  1.00 50.53 ? 190 THR A OG1 1 
ATOM   1330  C CG2 . THR A 1 190 ? 122.105 106.449 88.087  1.00 50.53 ? 190 THR A CG2 1 
ATOM   1331  N N   . VAL A 1 191 ? 123.630 103.317 88.514  1.00 46.89 ? 191 VAL A N   1 
ATOM   1332  C CA  . VAL A 1 191 ? 124.373 102.736 89.625  1.00 46.89 ? 191 VAL A CA  1 
ATOM   1333  C C   . VAL A 1 191 ? 125.432 103.735 90.053  1.00 46.89 ? 191 VAL A C   1 
ATOM   1334  O O   . VAL A 1 191 ? 126.166 104.255 89.209  1.00 46.89 ? 191 VAL A O   1 
ATOM   1335  C CB  . VAL A 1 191 ? 125.015 101.396 89.237  1.00 46.89 ? 191 VAL A CB  1 
ATOM   1336  C CG1 . VAL A 1 191 ? 125.700 100.788 90.420  1.00 46.89 ? 191 VAL A CG1 1 
ATOM   1337  C CG2 . VAL A 1 191 ? 123.986 100.467 88.694  1.00 46.89 ? 191 VAL A CG2 1 
ATOM   1338  N N   . THR A 1 192 ? 125.516 104.011 91.352  1.00 43.86 ? 192 THR A N   1 
ATOM   1339  C CA  . THR A 1 192 ? 126.398 105.052 91.854  1.00 43.86 ? 192 THR A CA  1 
ATOM   1340  C C   . THR A 1 192 ? 127.461 104.444 92.746  1.00 43.86 ? 192 THR A C   1 
ATOM   1341  O O   . THR A 1 192 ? 127.148 103.733 93.704  1.00 43.86 ? 192 THR A O   1 
ATOM   1342  C CB  . THR A 1 192 ? 125.624 106.109 92.634  1.00 43.86 ? 192 THR A CB  1 
ATOM   1343  O OG1 . THR A 1 192 ? 124.851 105.472 93.654  1.00 43.86 ? 192 THR A OG1 1 
ATOM   1344  C CG2 . THR A 1 192 ? 124.696 106.884 91.718  1.00 43.86 ? 192 THR A CG2 1 
ATOM   1345  N N   . ALA A 1 193 ? 128.709 104.740 92.438  1.00 44.47 ? 193 ALA A N   1 
ATOM   1346  C CA  . ALA A 1 193 ? 129.835 104.308 93.244  1.00 44.47 ? 193 ALA A CA  1 
ATOM   1347  C C   . ALA A 1 193 ? 130.490 105.521 93.883  1.00 44.47 ? 193 ALA A C   1 
ATOM   1348  O O   . ALA A 1 193 ? 130.714 106.534 93.220  1.00 44.47 ? 193 ALA A O   1 
ATOM   1349  C CB  . ALA A 1 193 ? 130.851 103.540 92.405  1.00 44.47 ? 193 ALA A CB  1 
ATOM   1350  N N   . LEU A 1 194 ? 130.792 105.413 95.165  1.00 42.59 ? 194 LEU A N   1 
ATOM   1351  C CA  . LEU A 1 194 ? 131.445 106.466 95.918  1.00 42.59 ? 194 LEU A CA  1 
ATOM   1352  C C   . LEU A 1 194 ? 132.893 106.070 96.124  1.00 42.59 ? 194 LEU A C   1 
ATOM   1353  O O   . LEU A 1 194 ? 133.175 104.977 96.622  1.00 42.59 ? 194 LEU A O   1 
ATOM   1354  C CB  . LEU A 1 194 ? 130.767 106.671 97.270  1.00 42.59 ? 194 LEU A CB  1 
ATOM   1355  C CG  . LEU A 1 194 ? 129.472 107.463 97.379  1.00 42.59 ? 194 LEU A CG  1 
ATOM   1356  C CD1 . LEU A 1 194 ? 129.735 108.882 96.985  1.00 42.59 ? 194 LEU A CD1 1 
ATOM   1357  C CD2 . LEU A 1 194 ? 128.367 106.862 96.532  1.00 42.59 ? 194 LEU A CD2 1 
ATOM   1358  N N   . ASP A 1 195 ? 133.804 106.941 95.722  1.00 48.30 ? 195 ASP A N   1 
ATOM   1359  C CA  . ASP A 1 195 ? 135.211 106.794 96.066  1.00 48.30 ? 195 ASP A CA  1 
ATOM   1360  C C   . ASP A 1 195 ? 135.408 107.611 97.326  1.00 48.30 ? 195 ASP A C   1 
ATOM   1361  O O   . ASP A 1 195 ? 135.440 108.841 97.267  1.00 48.30 ? 195 ASP A O   1 
ATOM   1362  C CB  . ASP A 1 195 ? 136.106 107.293 94.940  1.00 48.30 ? 195 ASP A CB  1 
ATOM   1363  C CG  . ASP A 1 195 ? 135.967 106.477 93.677  1.00 48.30 ? 195 ASP A CG  1 
ATOM   1364  O OD1 . ASP A 1 195 ? 135.669 105.268 93.764  1.00 48.30 ? 195 ASP A OD1 1 
ATOM   1365  O OD2 . ASP A 1 195 ? 136.157 107.049 92.585  1.00 48.30 ? 195 ASP A OD2 1 
ATOM   1366  N N   . MET A 1 196 ? 135.486 106.946 98.480  1.00 46.94 ? 196 MET A N   1 
ATOM   1367  C CA  . MET A 1 196 ? 135.575 107.679 99.740  1.00 46.94 ? 196 MET A CA  1 
ATOM   1368  C C   . MET A 1 196 ? 137.039 108.040 99.952  1.00 46.94 ? 196 MET A C   1 
ATOM   1369  O O   . MET A 1 196 ? 137.774 107.382 100.689 1.00 46.94 ? 196 MET A O   1 
ATOM   1370  C CB  . MET A 1 196 ? 135.030 106.852 100.895 1.00 46.94 ? 196 MET A CB  1 
ATOM   1371  C CG  . MET A 1 196 ? 133.552 106.596 100.873 1.00 46.94 ? 196 MET A CG  1 
ATOM   1372  S SD  . MET A 1 196 ? 132.618 108.115 100.876 1.00 46.94 ? 196 MET A SD  1 
ATOM   1373  C CE  . MET A 1 196 ? 131.006 107.502 101.325 1.00 46.94 ? 196 MET A CE  1 
ATOM   1374  N N   . GLN A 1 197 ? 137.472 109.094 99.269  1.00 46.24 ? 197 GLN A N   1 
ATOM   1375  C CA  . GLN A 1 197 ? 138.875 109.470 99.312  1.00 46.24 ? 197 GLN A CA  1 
ATOM   1376  C C   . GLN A 1 197 ? 139.350 109.633 100.743 1.00 46.24 ? 197 GLN A C   1 
ATOM   1377  O O   . GLN A 1 197 ? 138.590 110.035 101.625 1.00 46.24 ? 197 GLN A O   1 
ATOM   1378  C CB  . GLN A 1 197 ? 139.115 110.763 98.543  1.00 46.24 ? 197 GLN A CB  1 
ATOM   1379  C CG  . GLN A 1 197 ? 139.623 110.570 97.137  1.00 46.24 ? 197 GLN A CG  1 
ATOM   1380  C CD  . GLN A 1 197 ? 138.528 110.256 96.155  1.00 46.24 ? 197 GLN A CD  1 
ATOM   1381  O OE1 . GLN A 1 197 ? 137.355 110.474 96.429  1.00 46.24 ? 197 GLN A OE1 1 
ATOM   1382  N NE2 . GLN A 1 197 ? 138.906 109.739 94.996  1.00 46.24 ? 197 GLN A NE2 1 
ATOM   1383  N N   . ARG A 1 198 ? 140.617 109.286 100.972 1.00 50.99 ? 198 ARG A N   1 
ATOM   1384  C CA  . ARG A 1 198 ? 141.239 109.507 102.267 1.00 50.99 ? 198 ARG A CA  1 
ATOM   1385  C C   . ARG A 1 198 ? 141.361 110.988 102.579 1.00 50.99 ? 198 ARG A C   1 
ATOM   1386  O O   . ARG A 1 198 ? 141.624 111.352 103.729 1.00 50.99 ? 198 ARG A O   1 
ATOM   1387  C CB  . ARG A 1 198 ? 142.616 108.846 102.306 1.00 50.99 ? 198 ARG A CB  1 
ATOM   1388  C CG  . ARG A 1 198 ? 143.204 108.756 103.688 1.00 50.99 ? 198 ARG A CG  1 
ATOM   1389  C CD  . ARG A 1 198 ? 144.549 108.087 103.691 1.00 50.99 ? 198 ARG A CD  1 
ATOM   1390  N NE  . ARG A 1 198 ? 144.505 106.793 103.031 1.00 50.99 ? 198 ARG A NE  1 
ATOM   1391  C CZ  . ARG A 1 198 ? 145.512 105.931 103.026 1.00 50.99 ? 198 ARG A CZ  1 
ATOM   1392  N NH1 . ARG A 1 198 ? 146.626 106.214 103.683 1.00 50.99 ? 198 ARG A NH1 1 
ATOM   1393  N NH2 . ARG A 1 198 ? 145.394 104.775 102.392 1.00 50.99 ? 198 ARG A NH2 1 
ATOM   1394  N N   . SER A 1 199 ? 141.173 111.850 101.581 1.00 51.33 ? 199 SER A N   1 
ATOM   1395  C CA  . SER A 1 199 ? 141.161 113.292 101.781 1.00 51.33 ? 199 SER A CA  1 
ATOM   1396  C C   . SER A 1 199 ? 139.762 113.833 102.041 1.00 51.33 ? 199 SER A C   1 
ATOM   1397  O O   . SER A 1 199 ? 139.491 115.004 101.751 1.00 51.33 ? 199 SER A O   1 
ATOM   1398  C CB  . SER A 1 199 ? 141.789 113.982 100.574 1.00 51.33 ? 199 SER A CB  1 
ATOM   1399  O OG  . SER A 1 199 ? 143.132 113.565 100.412 1.00 51.33 ? 199 SER A OG  1 
ATOM   1400  N N   . ALA A 1 200 ? 138.863 112.995 102.552 1.00 45.62 ? 200 ALA A N   1 
ATOM   1401  C CA  . ALA A 1 200 ? 137.517 113.384 102.950 1.00 45.62 ? 200 ALA A CA  1 
ATOM   1402  C C   . ALA A 1 200 ? 136.687 113.882 101.777 1.00 45.62 ? 200 ALA A C   1 
ATOM   1403  O O   . ALA A 1 200 ? 135.529 114.270 101.955 1.00 45.62 ? 200 ALA A O   1 
ATOM   1404  C CB  . ALA A 1 200 ? 137.567 114.448 104.043 1.00 45.62 ? 200 ALA A CB  1 
ATOM   1405  N N   . ALA A 1 201 ? 137.253 113.853 100.579 1.00 46.92 ? 201 ALA A N   1 
ATOM   1406  C CA  . ALA A 1 201 ? 136.611 114.391 99.386  1.00 46.92 ? 201 ALA A CA  1 
ATOM   1407  C C   . ALA A 1 201 ? 136.050 113.239 98.562  1.00 46.92 ? 201 ALA A C   1 
ATOM   1408  O O   . ALA A 1 201 ? 136.666 112.798 97.594  1.00 46.92 ? 201 ALA A O   1 
ATOM   1409  C CB  . ALA A 1 201 ? 137.605 115.217 98.583  1.00 46.92 ? 201 ALA A CB  1 
ATOM   1410  N N   . CYS A 1 202 ? 134.865 112.770 98.933  1.00 46.83 ? 202 CYS A N   1 
ATOM   1411  C CA  . CYS A 1 202 ? 134.252 111.646 98.238  1.00 46.83 ? 202 CYS A CA  1 
ATOM   1412  C C   . CYS A 1 202 ? 133.901 112.022 96.805  1.00 46.83 ? 202 CYS A C   1 
ATOM   1413  O O   . CYS A 1 202 ? 133.476 113.145 96.531  1.00 46.83 ? 202 CYS A O   1 
ATOM   1414  C CB  . CYS A 1 202 ? 133.009 111.171 98.990  1.00 46.83 ? 202 CYS A CB  1 
ATOM   1415  S SG  . CYS A 1 202 ? 131.532 112.140 98.721  1.00 46.83 ? 202 CYS A SG  1 
ATOM   1416  N N   . THR A 1 203 ? 134.099 111.080 95.886  1.00 43.15 ? 203 THR A N   1 
ATOM   1417  C CA  . THR A 1 203 ? 133.890 111.324 94.464  1.00 43.15 ? 203 THR A CA  1 
ATOM   1418  C C   . THR A 1 203 ? 132.863 110.354 93.894  1.00 43.15 ? 203 THR A C   1 
ATOM   1419  O O   . THR A 1 203 ? 133.000 109.138 94.044  1.00 43.15 ? 203 THR A O   1 
ATOM   1420  C CB  . THR A 1 203 ? 135.204 111.211 93.699  1.00 43.15 ? 203 THR A CB  1 
ATOM   1421  O OG1 . THR A 1 203 ? 136.100 112.239 94.136  1.00 43.15 ? 203 THR A OG1 1 
ATOM   1422  C CG2 . THR A 1 203 ? 134.962 111.356 92.216  1.00 43.15 ? 203 THR A CG2 1 
ATOM   1423  N N   . LEU A 1 204 ? 131.856 110.897 93.220  1.00 41.35 ? 204 LEU A N   1 
ATOM   1424  C CA  . LEU A 1 204 ? 130.765 110.116 92.663  1.00 41.35 ? 204 LEU A CA  1 
ATOM   1425  C C   . LEU A 1 204 ? 131.118 109.560 91.284  1.00 41.35 ? 204 LEU A C   1 
ATOM   1426  O O   . LEU A 1 204 ? 131.855 110.174 90.510  1.00 41.35 ? 204 LEU A O   1 
ATOM   1427  C CB  . LEU A 1 204 ? 129.508 110.975 92.582  1.00 41.35 ? 204 LEU A CB  1 
ATOM   1428  C CG  . LEU A 1 204 ? 128.221 110.305 92.135  1.00 41.35 ? 204 LEU A CG  1 
ATOM   1429  C CD1 . LEU A 1 204 ? 128.022 109.051 92.919  1.00 41.35 ? 204 LEU A CD1 1 
ATOM   1430  C CD2 . LEU A 1 204 ? 127.060 111.227 92.357  1.00 41.35 ? 204 LEU A CD2 1 
ATOM   1431  N N   . LYS A 1 205 ? 130.591 108.370 90.994  1.00 45.72 ? 205 LYS A N   1 
ATOM   1432  C CA  . LYS A 1 205 ? 130.738 107.708 89.710  1.00 45.72 ? 205 LYS A CA  1 
ATOM   1433  C C   . LYS A 1 205 ? 129.389 107.150 89.315  1.00 45.72 ? 205 LYS A C   1 
ATOM   1434  O O   . LYS A 1 205 ? 128.695 106.574 90.152  1.00 45.72 ? 205 LYS A O   1 
ATOM   1435  C CB  . LYS A 1 205 ? 131.736 106.565 89.780  1.00 45.72 ? 205 LYS A CB  1 
ATOM   1436  C CG  . LYS A 1 205 ? 133.125 106.986 90.128  1.00 45.72 ? 205 LYS A CG  1 
ATOM   1437  C CD  . LYS A 1 205 ? 134.069 105.826 89.986  1.00 45.72 ? 205 LYS A CD  1 
ATOM   1438  C CE  . LYS A 1 205 ? 133.899 104.864 91.124  1.00 45.72 ? 205 LYS A CE  1 
ATOM   1439  N NZ  . LYS A 1 205 ? 134.891 103.767 91.044  1.00 45.72 ? 205 LYS A NZ  1 
ATOM   1440  N N   . THR A 1 206 ? 129.024 107.286 88.047  1.00 49.78 ? 206 THR A N   1 
ATOM   1441  C CA  . THR A 1 206 ? 127.707 106.873 87.600  1.00 49.78 ? 206 THR A CA  1 
ATOM   1442  C C   . THR A 1 206 ? 127.834 105.910 86.434  1.00 49.78 ? 206 THR A C   1 
ATOM   1443  O O   . THR A 1 206 ? 128.617 106.132 85.507  1.00 49.78 ? 206 THR A O   1 
ATOM   1444  C CB  . THR A 1 206 ? 126.855 108.074 87.186  1.00 49.78 ? 206 THR A CB  1 
ATOM   1445  O OG1 . THR A 1 206 ? 126.862 109.045 88.234  1.00 49.78 ? 206 THR A OG1 1 
ATOM   1446  C CG2 . THR A 1 206 ? 125.428 107.654 86.942  1.00 49.78 ? 206 THR A CG2 1 
ATOM   1447  N N   . ALA A 1 207 ? 127.047 104.847 86.484  1.00 51.43 ? 207 ALA A N   1 
ATOM   1448  C CA  . ALA A 1 207 ? 126.981 103.874 85.411  1.00 51.43 ? 207 ALA A CA  1 
ATOM   1449  C C   . ALA A 1 207 ? 125.556 103.776 84.901  1.00 51.43 ? 207 ALA A C   1 
ATOM   1450  O O   . ALA A 1 207 ? 124.603 103.761 85.690  1.00 51.43 ? 207 ALA A O   1 
ATOM   1451  C CB  . ALA A 1 207 ? 127.450 102.509 85.875  1.00 51.43 ? 207 ALA A CB  1 
ATOM   1452  N N   . PHE A 1 208 ? 125.430 103.698 83.580  1.00 52.20 ? 208 PHE A N   1 
ATOM   1453  C CA  . PHE A 1 208 ? 124.150 103.590 82.891  1.00 52.20 ? 208 PHE A CA  1 
ATOM   1454  C C   . PHE A 1 208 ? 124.085 102.266 82.144  1.00 52.20 ? 208 PHE A C   1 
ATOM   1455  O O   . PHE A 1 208 ? 124.877 102.049 81.203  1.00 52.20 ? 208 PHE A O   1 
ATOM   1456  C CB  . PHE A 1 208 ? 123.963 104.752 81.920  1.00 52.20 ? 208 PHE A CB  1 
ATOM   1457  C CG  . PHE A 1 208 ? 123.559 106.049 82.571  1.00 52.20 ? 208 PHE A CG  1 
ATOM   1458  C CD1 . PHE A 1 208 ? 122.413 106.133 83.335  1.00 52.20 ? 208 PHE A CD1 1 
ATOM   1459  C CD2 . PHE A 1 208 ? 124.310 107.191 82.386  1.00 52.20 ? 208 PHE A CD2 1 
ATOM   1460  C CE1 . PHE A 1 208 ? 122.044 107.329 83.918  1.00 52.20 ? 208 PHE A CE1 1 
ATOM   1461  C CE2 . PHE A 1 208 ? 123.944 108.381 82.969  1.00 52.20 ? 208 PHE A CE2 1 
ATOM   1462  C CZ  . PHE A 1 208 ? 122.813 108.449 83.731  1.00 52.20 ? 208 PHE A CZ  1 
ATOM   1463  N N   . PRO A 1 209 ? 123.222 101.341 82.553  1.00 55.62 ? 209 PRO A N   1 
ATOM   1464  C CA  . PRO A 1 209 ? 122.891 100.201 81.716  1.00 55.62 ? 209 PRO A CA  1 
ATOM   1465  C C   . PRO A 1 209 ? 121.730 100.529 80.803  1.00 55.62 ? 209 PRO A C   1 
ATOM   1466  O O   . PRO A 1 209 ? 120.638 100.884 81.271  1.00 55.62 ? 209 PRO A O   1 
ATOM   1467  C CB  . PRO A 1 209 ? 122.506 99.113  82.729  1.00 55.62 ? 209 PRO A CB  1 
ATOM   1468  C CG  . PRO A 1 209 ? 122.756 99.690  84.067  1.00 55.62 ? 209 PRO A CG  1 
ATOM   1469  C CD  . PRO A 1 209 ? 122.698 101.156 83.909  1.00 55.62 ? 209 PRO A CD  1 
ATOM   1470  N N   . PRO A 1 210 ? 121.916 100.408 79.499  1.00 60.29 ? 210 PRO A N   1 
ATOM   1471  C CA  . PRO A 1 210 ? 120.892 100.843 78.549  1.00 60.29 ? 210 PRO A CA  1 
ATOM   1472  C C   . PRO A 1 210 ? 119.821 99.809  78.258  1.00 60.29 ? 210 PRO A C   1 
ATOM   1473  O O   . PRO A 1 210 ? 119.154 99.916  77.228  1.00 60.29 ? 210 PRO A O   1 
ATOM   1474  C CB  . PRO A 1 210 ? 121.707 101.138 77.286  1.00 60.29 ? 210 PRO A CB  1 
ATOM   1475  C CG  . PRO A 1 210 ? 123.115 101.175 77.724  1.00 60.29 ? 210 PRO A CG  1 
ATOM   1476  C CD  . PRO A 1 210 ? 123.210 100.225 78.844  1.00 60.29 ? 210 PRO A CD  1 
ATOM   1477  N N   . LEU A 1 211 ? 119.662 98.803  79.116  1.00 61.50 ? 211 LEU A N   1 
ATOM   1478  C CA  . LEU A 1 211 ? 118.768 97.697  78.791  1.00 61.50 ? 211 LEU A CA  1 
ATOM   1479  C C   . LEU A 1 211 ? 117.343 98.177  78.543  1.00 61.50 ? 211 LEU A C   1 
ATOM   1480  O O   . LEU A 1 211 ? 116.714 97.784  77.557  1.00 61.50 ? 211 LEU A O   1 
ATOM   1481  C CB  . LEU A 1 211 ? 118.795 96.652  79.899  1.00 61.50 ? 211 LEU A CB  1 
ATOM   1482  C CG  . LEU A 1 211 ? 118.021 95.399  79.508  1.00 61.50 ? 211 LEU A CG  1 
ATOM   1483  C CD1 . LEU A 1 211 ? 118.697 94.740  78.334  1.00 61.50 ? 211 LEU A CD1 1 
ATOM   1484  C CD2 . LEU A 1 211 ? 117.911 94.446  80.671  1.00 61.50 ? 211 LEU A CD2 1 
ATOM   1485  N N   . LEU A 1 212 ? 116.816 99.031  79.421  1.00 61.20 ? 212 LEU A N   1 
ATOM   1486  C CA  . LEU A 1 212 ? 115.475 99.560  79.198  1.00 61.20 ? 212 LEU A CA  1 
ATOM   1487  C C   . LEU A 1 212 ? 115.423 100.443 77.960  1.00 61.20 ? 212 LEU A C   1 
ATOM   1488  O O   . LEU A 1 212 ? 114.439 100.411 77.213  1.00 61.20 ? 212 LEU A O   1 
ATOM   1489  C CB  . LEU A 1 212 ? 115.006 100.346 80.415  1.00 61.20 ? 212 LEU A CB  1 
ATOM   1490  C CG  . LEU A 1 212 ? 115.097 99.674  81.778  1.00 61.20 ? 212 LEU A CG  1 
ATOM   1491  C CD1 . LEU A 1 212 ? 114.922 100.703 82.857  1.00 61.20 ? 212 LEU A CD1 1 
ATOM   1492  C CD2 . LEU A 1 212 ? 114.043 98.616  81.902  1.00 61.20 ? 212 LEU A CD2 1 
ATOM   1493  N N   . ARG A 1 213 ? 116.466 101.241 77.730  1.00 62.60 ? 213 ARG A N   1 
ATOM   1494  C CA  . ARG A 1 213 ? 116.522 102.060 76.525  1.00 62.60 ? 213 ARG A CA  1 
ATOM   1495  C C   . ARG A 1 213 ? 116.519 101.196 75.275  1.00 62.60 ? 213 ARG A C   1 
ATOM   1496  O O   . ARG A 1 213 ? 115.658 101.346 74.402  1.00 62.60 ? 213 ARG A O   1 
ATOM   1497  C CB  . ARG A 1 213 ? 117.767 102.937 76.547  1.00 62.60 ? 213 ARG A CB  1 
ATOM   1498  C CG  . ARG A 1 213 ? 118.040 103.624 75.239  1.00 62.60 ? 213 ARG A CG  1 
ATOM   1499  C CD  . ARG A 1 213 ? 116.960 104.626 74.939  1.00 62.60 ? 213 ARG A CD  1 
ATOM   1500  N NE  . ARG A 1 213 ? 117.075 105.807 75.783  1.00 62.60 ? 213 ARG A NE  1 
ATOM   1501  C CZ  . ARG A 1 213 ? 116.097 106.681 75.982  1.00 62.60 ? 213 ARG A CZ  1 
ATOM   1502  N NH1 . ARG A 1 213 ? 114.921 106.507 75.400  1.00 62.60 ? 213 ARG A NH1 1 
ATOM   1503  N NH2 . ARG A 1 213 ? 116.298 107.728 76.766  1.00 62.60 ? 213 ARG A NH2 1 
ATOM   1504  N N   . SER A 1 214 ? 117.493 100.293 75.169  1.00 64.27 ? 214 SER A N   1 
ATOM   1505  C CA  . SER A 1 214 ? 117.570 99.413  74.014  1.00 64.27 ? 214 SER A CA  1 
ATOM   1506  C C   . SER A 1 214 ? 116.320 98.567  73.876  1.00 64.27 ? 214 SER A C   1 
ATOM   1507  O O   . SER A 1 214 ? 116.017 98.065  72.790  1.00 64.27 ? 214 SER A O   1 
ATOM   1508  C CB  . SER A 1 214 ? 118.796 98.523  74.127  1.00 64.27 ? 214 SER A CB  1 
ATOM   1509  O OG  . SER A 1 214 ? 118.813 97.865  75.376  1.00 64.27 ? 214 SER A OG  1 
ATOM   1510  N N   . THR A 1 215 ? 115.582 98.388  74.965  1.00 62.43 ? 215 THR A N   1 
ATOM   1511  C CA  . THR A 1 215 ? 114.355 97.613  74.879  1.00 62.43 ? 215 THR A CA  1 
ATOM   1512  C C   . THR A 1 215 ? 113.237 98.430  74.252  1.00 62.43 ? 215 THR A C   1 
ATOM   1513  O O   . THR A 1 215 ? 112.654 98.024  73.242  1.00 62.43 ? 215 THR A O   1 
ATOM   1514  C CB  . THR A 1 215 ? 113.953 97.116  76.259  1.00 62.43 ? 215 THR A CB  1 
ATOM   1515  O OG1 . THR A 1 215 ? 114.893 96.130  76.692  1.00 62.43 ? 215 THR A OG1 1 
ATOM   1516  C CG2 . THR A 1 215 ? 112.584 96.494  76.207  1.00 62.43 ? 215 THR A CG2 1 
ATOM   1517  N N   . ILE A 1 216 ? 112.921 99.587  74.836  1.00 65.09 ? 216 ILE A N   1 
ATOM   1518  C CA  . ILE A 1 216 ? 111.811 100.383 74.316  1.00 65.09 ? 216 ILE A CA  1 
ATOM   1519  C C   . ILE A 1 216 ? 112.108 100.849 72.900  1.00 65.09 ? 216 ILE A C   1 
ATOM   1520  O O   . ILE A 1 216 ? 111.239 100.805 72.025  1.00 65.09 ? 216 ILE A O   1 
ATOM   1521  C CB  . ILE A 1 216 ? 111.499 101.567 75.247  1.00 65.09 ? 216 ILE A CB  1 
ATOM   1522  C CG1 . ILE A 1 216 ? 112.770 102.346 75.583  1.00 65.09 ? 216 ILE A CG1 1 
ATOM   1523  C CG2 . ILE A 1 216 ? 110.800 101.087 76.501  1.00 65.09 ? 216 ILE A CG2 1 
ATOM   1524  C CD1 . ILE A 1 216 ? 112.555 103.476 76.553  1.00 65.09 ? 216 ILE A CD1 1 
ATOM   1525  N N   . MET A 1 217 ? 113.335 101.291 72.646  1.00 67.75 ? 217 MET A N   1 
ATOM   1526  C CA  . MET A 1 217 ? 113.724 101.650 71.293  1.00 67.75 ? 217 MET A CA  1 
ATOM   1527  C C   . MET A 1 217 ? 113.909 100.434 70.403  1.00 67.75 ? 217 MET A C   1 
ATOM   1528  O O   . MET A 1 217 ? 114.025 100.593 69.186  1.00 67.75 ? 217 MET A O   1 
ATOM   1529  C CB  . MET A 1 217 ? 115.007 102.478 71.317  1.00 67.75 ? 217 MET A CB  1 
ATOM   1530  C CG  . MET A 1 217 ? 114.839 103.823 71.990  1.00 67.75 ? 217 MET A CG  1 
ATOM   1531  S SD  . MET A 1 217 ? 116.092 105.015 71.497  1.00 67.75 ? 217 MET A SD  1 
ATOM   1532  C CE  . MET A 1 217 ? 115.986 104.894 69.717  1.00 67.75 ? 217 MET A CE  1 
ATOM   1533  N N   . ASN A 1 218 ? 113.940 99.236  70.982  1.00 70.04 ? 218 ASN A N   1 
ATOM   1534  C CA  . ASN A 1 218 ? 114.039 97.992  70.225  1.00 70.04 ? 218 ASN A CA  1 
ATOM   1535  C C   . ASN A 1 218 ? 115.286 97.971  69.349  1.00 70.04 ? 218 ASN A C   1 
ATOM   1536  O O   . ASN A 1 218 ? 115.286 97.415  68.251  1.00 70.04 ? 218 ASN A O   1 
ATOM   1537  C CB  . ASN A 1 218 ? 112.782 97.754  69.388  1.00 70.04 ? 218 ASN A CB  1 
ATOM   1538  C CG  . ASN A 1 218 ? 111.559 97.494  70.239  1.00 70.04 ? 218 ASN A CG  1 
ATOM   1539  O OD1 . ASN A 1 218 ? 111.190 96.346  70.480  1.00 70.04 ? 218 ASN A OD1 1 
ATOM   1540  N ND2 . ASN A 1 218 ? 110.922 98.562  70.702  1.00 70.04 ? 218 ASN A ND2 1 
ATOM   1541  N N   . THR A 1 219 ? 116.359 98.581  69.835  1.00 68.43 ? 219 THR A N   1 
ATOM   1542  C CA  . THR A 1 219 ? 117.616 98.626  69.111  1.00 68.43 ? 219 THR A CA  1 
ATOM   1543  C C   . THR A 1 219 ? 118.699 97.913  69.905  1.00 68.43 ? 219 THR A C   1 
ATOM   1544  O O   . THR A 1 219 ? 118.520 97.568  71.074  1.00 68.43 ? 219 THR A O   1 
ATOM   1545  C CB  . THR A 1 219 ? 118.043 100.063 68.830  1.00 68.43 ? 219 THR A CB  1 
ATOM   1546  O OG1 . THR A 1 219 ? 118.217 100.748 70.071  1.00 68.43 ? 219 THR A OG1 1 
ATOM   1547  C CG2 . THR A 1 219 ? 116.982 100.773 68.015  1.00 68.43 ? 219 THR A CG2 1 
ATOM   1548  N N   . SER A 1 220 ? 119.833 97.697  69.250  1.00 70.20 ? 220 SER A N   1 
ATOM   1549  C CA  . SER A 1 220 ? 120.903 96.923  69.857  1.00 70.20 ? 220 SER A CA  1 
ATOM   1550  C C   . SER A 1 220 ? 121.665 97.754  70.877  1.00 70.20 ? 220 SER A C   1 
ATOM   1551  O O   . SER A 1 220 ? 121.899 98.951  70.683  1.00 70.20 ? 220 SER A O   1 
ATOM   1552  C CB  . SER A 1 220 ? 121.855 96.406  68.783  1.00 70.20 ? 220 SER A CB  1 
ATOM   1553  O OG  . SER A 1 220 ? 121.302 95.283  68.126  1.00 70.20 ? 220 SER A OG  1 
ATOM   1554  N N   . MET A 1 221 ? 122.046 97.098  71.975  1.00 71.50 ? 221 MET A N   1 
ATOM   1555  C CA  . MET A 1 221 ? 122.805 97.759  73.029  1.00 71.50 ? 221 MET A CA  1 
ATOM   1556  C C   . MET A 1 221 ? 124.049 98.422  72.464  1.00 71.50 ? 221 MET A C   1 
ATOM   1557  O O   . MET A 1 221 ? 124.345 99.589  72.756  1.00 71.50 ? 221 MET A O   1 
ATOM   1558  C CB  . MET A 1 221 ? 123.196 96.740  74.097  1.00 71.50 ? 221 MET A CB  1 
ATOM   1559  C CG  . MET A 1 221 ? 122.129 95.704  74.429  1.00 71.50 ? 221 MET A CG  1 
ATOM   1560  S SD  . MET A 1 221 ? 120.849 96.284  75.551  1.00 71.50 ? 221 MET A SD  1 
ATOM   1561  C CE  . MET A 1 221 ? 121.795 96.599  77.031  1.00 71.50 ? 221 MET A CE  1 
ATOM   1562  N N   . VAL A 1 222 ? 124.791 97.673  71.651  1.00 72.14 ? 222 VAL A N   1 
ATOM   1563  C CA  . VAL A 1 222 ? 126.012 98.188  71.039  1.00 72.14 ? 222 VAL A CA  1 
ATOM   1564  C C   . VAL A 1 222 ? 125.740 99.528  70.376  1.00 72.14 ? 222 VAL A C   1 
ATOM   1565  O O   . VAL A 1 222 ? 126.461 100.515 70.583  1.00 72.14 ? 222 VAL A O   1 
ATOM   1566  C CB  . VAL A 1 222 ? 126.556 97.164  70.028  1.00 72.14 ? 222 VAL A CB  1 
ATOM   1567  C CG1 . VAL A 1 222 ? 127.980 97.499  69.636  1.00 72.14 ? 222 VAL A CG1 1 
ATOM   1568  C CG2 . VAL A 1 222 ? 126.451 95.758  70.593  1.00 72.14 ? 222 VAL A CG2 1 
ATOM   1569  N N   . ASP A 1 223 ? 124.664 99.588  69.595  1.00 73.64 ? 223 ASP A N   1 
ATOM   1570  C CA  . ASP A 1 223 ? 124.418 100.753 68.760  1.00 73.64 ? 223 ASP A CA  1 
ATOM   1571  C C   . ASP A 1 223 ? 124.095 101.983 69.592  1.00 73.64 ? 223 ASP A C   1 
ATOM   1572  O O   . ASP A 1 223 ? 124.681 103.047 69.377  1.00 73.64 ? 223 ASP A O   1 
ATOM   1573  C CB  . ASP A 1 223 ? 123.303 100.461 67.763  1.00 73.64 ? 223 ASP A CB  1 
ATOM   1574  C CG  . ASP A 1 223 ? 123.740 99.502  66.684  1.00 73.64 ? 223 ASP A CG  1 
ATOM   1575  O OD1 . ASP A 1 223 ? 124.942 99.509  66.348  1.00 73.64 ? 223 ASP A OD1 1 
ATOM   1576  O OD2 . ASP A 1 223 ? 122.886 98.750  66.173  1.00 73.64 ? 223 ASP A OD2 1 
ATOM   1577  N N   . ILE A 1 224 ? 123.160 101.875 70.537  1.00 68.40 ? 224 ILE A N   1 
ATOM   1578  C CA  . ILE A 1 224 ? 122.820 103.065 71.309  1.00 68.40 ? 224 ILE A CA  1 
ATOM   1579  C C   . ILE A 1 224 ? 124.009 103.513 72.143  1.00 68.40 ? 224 ILE A C   1 
ATOM   1580  O O   . ILE A 1 224 ? 124.304 104.710 72.229  1.00 68.40 ? 224 ILE A O   1 
ATOM   1581  C CB  . ILE A 1 224 ? 121.574 102.833 72.176  1.00 68.40 ? 224 ILE A CB  1 
ATOM   1582  C CG1 . ILE A 1 224 ? 121.753 101.637 73.083  1.00 68.40 ? 224 ILE A CG1 1 
ATOM   1583  C CG2 . ILE A 1 224 ? 120.371 102.609 71.309  1.00 68.40 ? 224 ILE A CG2 1 
ATOM   1584  C CD1 . ILE A 1 224 ? 120.594 101.451 73.966  1.00 68.40 ? 224 ILE A CD1 1 
ATOM   1585  N N   . MET A 1 225 ? 124.731 102.565 72.742  1.00 70.10 ? 225 MET A N   1 
ATOM   1586  C CA  . MET A 1 225 ? 125.886 102.939 73.549  1.00 70.10 ? 225 MET A CA  1 
ATOM   1587  C C   . MET A 1 225 ? 126.896 103.723 72.727  1.00 70.10 ? 225 MET A C   1 
ATOM   1588  O O   . MET A 1 225 ? 127.326 104.820 73.116  1.00 70.10 ? 225 MET A O   1 
ATOM   1589  C CB  . MET A 1 225 ? 126.534 101.692 74.141  1.00 70.10 ? 225 MET A CB  1 
ATOM   1590  C CG  . MET A 1 225 ? 125.772 101.082 75.302  1.00 70.10 ? 225 MET A CG  1 
ATOM   1591  S SD  . MET A 1 225 ? 126.641 99.685  76.030  1.00 70.10 ? 225 MET A SD  1 
ATOM   1592  C CE  . MET A 1 225 ? 125.272 98.633  76.495  1.00 70.10 ? 225 MET A CE  1 
ATOM   1593  N N   . PHE A 1 226 ? 127.272 103.191 71.567  1.00 70.78 ? 226 PHE A N   1 
ATOM   1594  C CA  . PHE A 1 226 ? 128.342 103.826 70.815  1.00 70.78 ? 226 PHE A CA  1 
ATOM   1595  C C   . PHE A 1 226 ? 127.872 105.063 70.069  1.00 70.78 ? 226 PHE A C   1 
ATOM   1596  O O   . PHE A 1 226 ? 128.661 105.984 69.857  1.00 70.78 ? 226 PHE A O   1 
ATOM   1597  C CB  . PHE A 1 226 ? 128.973 102.811 69.881  1.00 70.78 ? 226 PHE A CB  1 
ATOM   1598  C CG  . PHE A 1 226 ? 129.813 101.818 70.601  1.00 70.78 ? 226 PHE A CG  1 
ATOM   1599  C CD1 . PHE A 1 226 ? 130.945 102.228 71.276  1.00 70.78 ? 226 PHE A CD1 1 
ATOM   1600  C CD2 . PHE A 1 226 ? 129.452 100.488 70.651  1.00 70.78 ? 226 PHE A CD2 1 
ATOM   1601  C CE1 . PHE A 1 226 ? 131.718 101.325 71.959  1.00 70.78 ? 226 PHE A CE1 1 
ATOM   1602  C CE2 . PHE A 1 226 ? 130.222 99.580  71.331  1.00 70.78 ? 226 PHE A CE2 1 
ATOM   1603  C CZ  . PHE A 1 226 ? 131.356 99.999  71.987  1.00 70.78 ? 226 PHE A CZ  1 
ATOM   1604  N N   . ASP A 1 227 ? 126.593 105.146 69.720  1.00 68.98 ? 227 ASP A N   1 
ATOM   1605  C CA  . ASP A 1 227 ? 126.089 106.382 69.146  1.00 68.98 ? 227 ASP A CA  1 
ATOM   1606  C C   . ASP A 1 227 ? 126.054 107.490 70.186  1.00 68.98 ? 227 ASP A C   1 
ATOM   1607  O O   . ASP A 1 227 ? 126.323 108.655 69.870  1.00 68.98 ? 227 ASP A O   1 
ATOM   1608  C CB  . ASP A 1 227 ? 124.707 106.152 68.546  1.00 68.98 ? 227 ASP A CB  1 
ATOM   1609  C CG  . ASP A 1 227 ? 124.758 105.312 67.288  1.00 68.98 ? 227 ASP A CG  1 
ATOM   1610  O OD1 . ASP A 1 227 ? 125.852 104.816 66.944  1.00 68.98 ? 227 ASP A OD1 1 
ATOM   1611  O OD2 . ASP A 1 227 ? 123.705 105.147 66.641  1.00 68.98 ? 227 ASP A OD2 1 
ATOM   1612  N N   . ALA A 1 228 ? 125.737 107.150 71.436  1.00 65.51 ? 228 ALA A N   1 
ATOM   1613  C CA  . ALA A 1 228 ? 125.810 108.142 72.500  1.00 65.51 ? 228 ALA A CA  1 
ATOM   1614  C C   . ALA A 1 228 ? 127.238 108.629 72.692  1.00 65.51 ? 228 ALA A C   1 
ATOM   1615  O O   . ALA A 1 228 ? 127.495 109.838 72.756  1.00 65.51 ? 228 ALA A O   1 
ATOM   1616  C CB  . ALA A 1 228 ? 125.254 107.560 73.795  1.00 65.51 ? 228 ALA A CB  1 
ATOM   1617  N N   . VAL A 1 229 ? 128.192 107.701 72.780  1.00 69.96 ? 229 VAL A N   1 
ATOM   1618  C CA  . VAL A 1 229 ? 129.569 108.151 72.957  1.00 69.96 ? 229 VAL A CA  1 
ATOM   1619  C C   . VAL A 1 229 ? 130.032 108.958 71.748  1.00 69.96 ? 229 VAL A C   1 
ATOM   1620  O O   . VAL A 1 229 ? 130.826 109.895 71.886  1.00 69.96 ? 229 VAL A O   1 
ATOM   1621  C CB  . VAL A 1 229 ? 130.516 106.971 73.260  1.00 69.96 ? 229 VAL A CB  1 
ATOM   1622  C CG1 . VAL A 1 229 ? 130.799 106.157 72.025  1.00 69.96 ? 229 VAL A CG1 1 
ATOM   1623  C CG2 . VAL A 1 229 ? 131.814 107.489 73.841  1.00 69.96 ? 229 VAL A CG2 1 
ATOM   1624  N N   . GLU A 1 230 ? 129.509 108.657 70.557  1.00 72.84 ? 230 GLU A N   1 
ATOM   1625  C CA  . GLU A 1 230 ? 129.914 109.396 69.367  1.00 72.84 ? 230 GLU A CA  1 
ATOM   1626  C C   . GLU A 1 230 ? 129.370 110.816 69.384  1.00 72.84 ? 230 GLU A C   1 
ATOM   1627  O O   . GLU A 1 230 ? 130.088 111.776 69.065  1.00 72.84 ? 230 GLU A O   1 
ATOM   1628  C CB  . GLU A 1 230 ? 129.440 108.661 68.118  1.00 72.84 ? 230 GLU A CB  1 
ATOM   1629  C CG  . GLU A 1 230 ? 129.666 109.434 66.851  1.00 72.84 ? 230 GLU A CG  1 
ATOM   1630  C CD  . GLU A 1 230 ? 131.122 109.767 66.650  1.00 72.84 ? 230 GLU A CD  1 
ATOM   1631  O OE1 . GLU A 1 230 ? 131.972 108.909 66.958  1.00 72.84 ? 230 GLU A OE1 1 
ATOM   1632  O OE2 . GLU A 1 230 ? 131.424 110.885 66.191  1.00 72.84 ? 230 GLU A OE2 1 
ATOM   1633  N N   . SER A 1 231 ? 128.091 110.969 69.728  1.00 68.22 ? 231 SER A N   1 
ATOM   1634  C CA  . SER A 1 231 ? 127.529 112.309 69.820  1.00 68.22 ? 231 SER A CA  1 
ATOM   1635  C C   . SER A 1 231 ? 128.260 113.120 70.875  1.00 68.22 ? 231 SER A C   1 
ATOM   1636  O O   . SER A 1 231 ? 128.477 114.322 70.699  1.00 68.22 ? 231 SER A O   1 
ATOM   1637  C CB  . SER A 1 231 ? 126.036 112.256 70.131  1.00 68.22 ? 231 SER A CB  1 
ATOM   1638  O OG  . SER A 1 231 ? 125.805 111.880 71.470  1.00 68.22 ? 231 SER A OG  1 
ATOM   1639  N N   . PHE A 1 232 ? 128.666 112.481 71.972  1.00 67.69 ? 232 PHE A N   1 
ATOM   1640  C CA  . PHE A 1 232 ? 129.445 113.210 72.964  1.00 67.69 ? 232 PHE A CA  1 
ATOM   1641  C C   . PHE A 1 232 ? 130.805 113.599 72.413  1.00 67.69 ? 232 PHE A C   1 
ATOM   1642  O O   . PHE A 1 232 ? 131.308 114.691 72.692  1.00 67.69 ? 232 PHE A O   1 
ATOM   1643  C CB  . PHE A 1 232 ? 129.612 112.388 74.237  1.00 67.69 ? 232 PHE A CB  1 
ATOM   1644  C CG  . PHE A 1 232 ? 130.278 113.142 75.349  1.00 67.69 ? 232 PHE A CG  1 
ATOM   1645  C CD1 . PHE A 1 232 ? 129.596 114.124 76.038  1.00 67.69 ? 232 PHE A CD1 1 
ATOM   1646  C CD2 . PHE A 1 232 ? 131.588 112.887 75.687  1.00 67.69 ? 232 PHE A CD2 1 
ATOM   1647  C CE1 . PHE A 1 232 ? 130.205 114.825 77.048  1.00 67.69 ? 232 PHE A CE1 1 
ATOM   1648  C CE2 . PHE A 1 232 ? 132.199 113.588 76.695  1.00 67.69 ? 232 PHE A CE2 1 
ATOM   1649  C CZ  . PHE A 1 232 ? 131.506 114.558 77.375  1.00 67.69 ? 232 PHE A CZ  1 
ATOM   1650  N N   . ARG A 1 233 ? 131.420 112.710 71.636  1.00 75.49 ? 233 ARG A N   1 
ATOM   1651  C CA  . ARG A 1 233 ? 132.714 113.021 71.043  1.00 75.49 ? 233 ARG A CA  1 
ATOM   1652  C C   . ARG A 1 233 ? 132.633 114.250 70.155  1.00 75.49 ? 233 ARG A C   1 
ATOM   1653  O O   . ARG A 1 233 ? 133.533 115.097 70.164  1.00 75.49 ? 233 ARG A O   1 
ATOM   1654  C CB  . ARG A 1 233 ? 133.215 111.829 70.241  1.00 75.49 ? 233 ARG A CB  1 
ATOM   1655  C CG  . ARG A 1 233 ? 133.796 110.738 71.082  1.00 75.49 ? 233 ARG A CG  1 
ATOM   1656  C CD  . ARG A 1 233 ? 134.547 109.782 70.201  1.00 75.49 ? 233 ARG A CD  1 
ATOM   1657  N NE  . ARG A 1 233 ? 135.233 110.488 69.129  1.00 75.49 ? 233 ARG A NE  1 
ATOM   1658  C CZ  . ARG A 1 233 ? 135.933 109.888 68.177  1.00 75.49 ? 233 ARG A CZ  1 
ATOM   1659  N NH1 . ARG A 1 233 ? 136.039 108.568 68.166  1.00 75.49 ? 233 ARG A NH1 1 
ATOM   1660  N NH2 . ARG A 1 233 ? 136.527 110.607 67.237  1.00 75.49 ? 233 ARG A NH2 1 
ATOM   1661  N N   . LYS A 1 234 ? 131.561 114.366 69.378  1.00 75.18 ? 234 LYS A N   1 
ATOM   1662  C CA  . LYS A 1 234 ? 131.474 115.496 68.461  1.00 75.18 ? 234 LYS A CA  1 
ATOM   1663  C C   . LYS A 1 234 ? 131.049 116.767 69.184  1.00 75.18 ? 234 LYS A C   1 
ATOM   1664  O O   . LYS A 1 234 ? 131.630 117.835 68.967  1.00 75.18 ? 234 LYS A O   1 
ATOM   1665  C CB  . LYS A 1 234 ? 130.527 115.176 67.310  1.00 75.18 ? 234 LYS A CB  1 
ATOM   1666  C CG  . LYS A 1 234 ? 130.962 113.980 66.475  1.00 75.18 ? 234 LYS A CG  1 
ATOM   1667  C CD  . LYS A 1 234 ? 132.258 114.238 65.701  1.00 75.18 ? 234 LYS A CD  1 
ATOM   1668  C CE  . LYS A 1 234 ? 133.481 113.643 66.408  1.00 75.18 ? 234 LYS A CE  1 
ATOM   1669  N NZ  . LYS A 1 234 ? 134.731 113.795 65.617  1.00 75.18 ? 234 LYS A NZ  1 
ATOM   1670  N N   . GLN A 1 235 ? 130.047 116.674 70.057  1.00 72.87 ? 235 GLN A N   1 
ATOM   1671  C CA  . GLN A 1 235 ? 129.600 117.835 70.814  1.00 72.87 ? 235 GLN A CA  1 
ATOM   1672  C C   . GLN A 1 235 ? 130.691 118.387 71.720  1.00 72.87 ? 235 GLN A C   1 
ATOM   1673  O O   . GLN A 1 235 ? 130.718 119.592 71.975  1.00 72.87 ? 235 GLN A O   1 
ATOM   1674  C CB  . GLN A 1 235 ? 128.367 117.457 71.638  1.00 72.87 ? 235 GLN A CB  1 
ATOM   1675  C CG  . GLN A 1 235 ? 127.810 118.555 72.515  1.00 72.87 ? 235 GLN A CG  1 
ATOM   1676  C CD  . GLN A 1 235 ? 128.515 118.625 73.845  1.00 72.87 ? 235 GLN A CD  1 
ATOM   1677  O OE1 . GLN A 1 235 ? 129.131 117.656 74.278  1.00 72.87 ? 235 GLN A OE1 1 
ATOM   1678  N NE2 . GLN A 1 235 ? 128.447 119.776 74.495  1.00 72.87 ? 235 GLN A NE2 1 
ATOM   1679  N N   . SER A 1 236 ? 131.588 117.540 72.208  1.00 73.72 ? 236 SER A N   1 
ATOM   1680  C CA  . SER A 1 236 ? 132.624 117.959 73.138  1.00 73.72 ? 236 SER A CA  1 
ATOM   1681  C C   . SER A 1 236 ? 133.978 118.133 72.483  1.00 73.72 ? 236 SER A C   1 
ATOM   1682  O O   . SER A 1 236 ? 134.823 118.858 73.018  1.00 73.72 ? 236 SER A O   1 
ATOM   1683  C CB  . SER A 1 236 ? 132.755 116.936 74.270  1.00 73.72 ? 236 SER A CB  1 
ATOM   1684  O OG  . SER A 1 236 ? 133.029 115.646 73.756  1.00 73.72 ? 236 SER A OG  1 
ATOM   1685  N N   . GLY A 1 237 ? 134.208 117.480 71.349  1.00 77.91 ? 237 GLY A N   1 
ATOM   1686  C CA  . GLY A 1 237 ? 135.502 117.504 70.723  1.00 77.91 ? 237 GLY A CA  1 
ATOM   1687  C C   . GLY A 1 237 ? 136.515 116.563 71.327  1.00 77.91 ? 237 GLY A C   1 
ATOM   1688  O O   . GLY A 1 237 ? 137.566 116.338 70.714  1.00 77.91 ? 237 GLY A O   1 
ATOM   1689  N N   . LEU A 1 238 ? 136.244 116.001 72.498  1.00 77.74 ? 238 LEU A N   1 
ATOM   1690  C CA  . LEU A 1 238 ? 137.226 115.149 73.141  1.00 77.74 ? 238 LEU A CA  1 
ATOM   1691  C C   . LEU A 1 238 ? 137.289 113.790 72.450  1.00 77.74 ? 238 LEU A C   1 
ATOM   1692  O O   . LEU A 1 238 ? 136.373 113.383 71.732  1.00 77.74 ? 238 LEU A O   1 
ATOM   1693  C CB  . LEU A 1 238 ? 136.911 114.987 74.627  1.00 77.74 ? 238 LEU A CB  1 
ATOM   1694  C CG  . LEU A 1 238 ? 137.220 116.208 75.497  1.00 77.74 ? 238 LEU A CG  1 
ATOM   1695  C CD1 . LEU A 1 238 ? 136.050 117.163 75.540  1.00 77.74 ? 238 LEU A CD1 1 
ATOM   1696  C CD2 . LEU A 1 238 ? 137.613 115.796 76.894  1.00 77.74 ? 238 LEU A CD2 1 
ATOM   1697  N N   . TYR A 1 239 ? 138.391 113.086 72.688  1.00 82.42 ? 239 TYR A N   1 
ATOM   1698  C CA  . TYR A 1 239 ? 138.759 111.897 71.933  1.00 82.42 ? 239 TYR A CA  1 
ATOM   1699  C C   . TYR A 1 239 ? 138.472 110.652 72.762  1.00 82.42 ? 239 TYR A C   1 
ATOM   1700  O O   . TYR A 1 239 ? 139.192 110.369 73.721  1.00 82.42 ? 239 TYR A O   1 
ATOM   1701  C CB  . TYR A 1 239 ? 140.239 111.960 71.563  1.00 82.42 ? 239 TYR A CB  1 
ATOM   1702  C CG  . TYR A 1 239 ? 140.662 111.026 70.460  1.00 82.42 ? 239 TYR A CG  1 
ATOM   1703  C CD1 . TYR A 1 239 ? 140.466 109.658 70.565  1.00 82.42 ? 239 TYR A CD1 1 
ATOM   1704  C CD2 . TYR A 1 239 ? 141.287 111.511 69.325  1.00 82.42 ? 239 TYR A CD2 1 
ATOM   1705  C CE1 . TYR A 1 239 ? 140.855 108.805 69.562  1.00 82.42 ? 239 TYR A CE1 1 
ATOM   1706  C CE2 . TYR A 1 239 ? 141.686 110.664 68.317  1.00 82.42 ? 239 TYR A CE2 1 
ATOM   1707  C CZ  . TYR A 1 239 ? 141.470 109.311 68.442  1.00 82.42 ? 239 TYR A CZ  1 
ATOM   1708  O OH  . TYR A 1 239 ? 141.866 108.460 67.437  1.00 82.42 ? 239 TYR A OH  1 
ATOM   1709  N N   . PHE A 1 240 ? 137.448 109.894 72.373  1.00 78.42 ? 240 PHE A N   1 
ATOM   1710  C CA  . PHE A 1 240 ? 137.086 108.647 73.048  1.00 78.42 ? 240 PHE A CA  1 
ATOM   1711  C C   . PHE A 1 240 ? 137.123 107.518 72.022  1.00 78.42 ? 240 PHE A C   1 
ATOM   1712  O O   . PHE A 1 240 ? 136.107 107.220 71.390  1.00 78.42 ? 240 PHE A O   1 
ATOM   1713  C CB  . PHE A 1 240 ? 135.705 108.741 73.690  1.00 78.42 ? 240 PHE A CB  1 
ATOM   1714  C CG  . PHE A 1 240 ? 135.658 109.594 74.919  1.00 78.42 ? 240 PHE A CG  1 
ATOM   1715  C CD1 . PHE A 1 240 ? 136.651 109.512 75.874  1.00 78.42 ? 240 PHE A CD1 1 
ATOM   1716  C CD2 . PHE A 1 240 ? 134.606 110.457 75.135  1.00 78.42 ? 240 PHE A CD2 1 
ATOM   1717  C CE1 . PHE A 1 240 ? 136.602 110.285 77.010  1.00 78.42 ? 240 PHE A CE1 1 
ATOM   1718  C CE2 . PHE A 1 240 ? 134.556 111.233 76.271  1.00 78.42 ? 240 PHE A CE2 1 
ATOM   1719  C CZ  . PHE A 1 240 ? 135.556 111.148 77.207  1.00 78.42 ? 240 PHE A CZ  1 
ATOM   1720  N N   . ASP A 1 241 ? 138.276 106.876 71.860  1.00 81.35 ? 241 ASP A N   1 
ATOM   1721  C CA  . ASP A 1 241 ? 138.395 105.836 70.844  1.00 81.35 ? 241 ASP A CA  1 
ATOM   1722  C C   . ASP A 1 241 ? 137.511 104.656 71.219  1.00 81.35 ? 241 ASP A C   1 
ATOM   1723  O O   . ASP A 1 241 ? 137.772 103.963 72.205  1.00 81.35 ? 241 ASP A O   1 
ATOM   1724  C CB  . ASP A 1 241 ? 139.846 105.401 70.680  1.00 81.35 ? 241 ASP A CB  1 
ATOM   1725  C CG  . ASP A 1 241 ? 140.082 104.675 69.369  1.00 81.35 ? 241 ASP A CG  1 
ATOM   1726  O OD1 . ASP A 1 241 ? 139.967 105.318 68.307  1.00 81.35 ? 241 ASP A OD1 1 
ATOM   1727  O OD2 . ASP A 1 241 ? 140.371 103.460 69.397  1.00 81.35 ? 241 ASP A OD2 1 
ATOM   1728  N N   . TYR A 1 242 ? 136.470 104.420 70.423  1.00 77.14 ? 242 TYR A N   1 
ATOM   1729  C CA  . TYR A 1 242 ? 135.475 103.391 70.698  1.00 77.14 ? 242 TYR A CA  1 
ATOM   1730  C C   . TYR A 1 242 ? 135.330 102.383 69.566  1.00 77.14 ? 242 TYR A C   1 
ATOM   1731  O O   . TYR A 1 242 ? 134.409 101.565 69.600  1.00 77.14 ? 242 TYR A O   1 
ATOM   1732  C CB  . TYR A 1 242 ? 134.118 104.039 70.960  1.00 77.14 ? 242 TYR A CB  1 
ATOM   1733  C CG  . TYR A 1 242 ? 133.559 104.684 69.721  1.00 77.14 ? 242 TYR A CG  1 
ATOM   1734  C CD1 . TYR A 1 242 ? 133.999 105.928 69.311  1.00 77.14 ? 242 TYR A CD1 1 
ATOM   1735  C CD2 . TYR A 1 242 ? 132.608 104.039 68.946  1.00 77.14 ? 242 TYR A CD2 1 
ATOM   1736  C CE1 . TYR A 1 242 ? 133.502 106.520 68.174  1.00 77.14 ? 242 TYR A CE1 1 
ATOM   1737  C CE2 . TYR A 1 242 ? 132.104 104.624 67.806  1.00 77.14 ? 242 TYR A CE2 1 
ATOM   1738  C CZ  . TYR A 1 242 ? 132.554 105.866 67.426  1.00 77.14 ? 242 TYR A CZ  1 
ATOM   1739  O OH  . TYR A 1 242 ? 132.059 106.461 66.292  1.00 77.14 ? 242 TYR A OH  1 
ATOM   1740  N N   . THR A 1 243 ? 136.192 102.425 68.555  1.00 78.45 ? 243 THR A N   1 
ATOM   1741  C CA  . THR A 1 243 ? 135.967 101.597 67.377  1.00 78.45 ? 243 THR A CA  1 
ATOM   1742  C C   . THR A 1 243 ? 136.197 100.119 67.673  1.00 78.45 ? 243 THR A C   1 
ATOM   1743  O O   . THR A 1 243 ? 135.346 99.281  67.363  1.00 78.45 ? 243 THR A O   1 
ATOM   1744  C CB  . THR A 1 243 ? 136.845 102.076 66.219  1.00 78.45 ? 243 THR A CB  1 
ATOM   1745  O OG1 . THR A 1 243 ? 136.691 101.190 65.105  1.00 78.45 ? 243 THR A OG1 1 
ATOM   1746  C CG2 . THR A 1 243 ? 138.306 102.177 66.619  1.00 78.45 ? 243 THR A CG2 1 
ATOM   1747  N N   . LYS A 1 244 ? 137.325 99.780  68.294  1.00 75.83 ? 244 LYS A N   1 
ATOM   1748  C CA  . LYS A 1 244 ? 137.694 98.377  68.444  1.00 75.83 ? 244 LYS A CA  1 
ATOM   1749  C C   . LYS A 1 244 ? 136.703 97.633  69.321  1.00 75.83 ? 244 LYS A C   1 
ATOM   1750  O O   . LYS A 1 244 ? 136.405 96.457  69.075  1.00 75.83 ? 244 LYS A O   1 
ATOM   1751  C CB  . LYS A 1 244 ? 139.101 98.278  69.017  1.00 75.83 ? 244 LYS A CB  1 
ATOM   1752  C CG  . LYS A 1 244 ? 140.103 99.067  68.229  1.00 75.83 ? 244 LYS A CG  1 
ATOM   1753  C CD  . LYS A 1 244 ? 141.333 99.346  69.046  1.00 75.83 ? 244 LYS A CD  1 
ATOM   1754  C CE  . LYS A 1 244 ? 141.024 100.319 70.156  1.00 75.83 ? 244 LYS A CE  1 
ATOM   1755  N NZ  . LYS A 1 244 ? 142.257 100.668 70.905  1.00 75.83 ? 244 LYS A NZ  1 
ATOM   1756  N N   . ILE A 1 245 ? 136.188 98.298  70.354  1.00 75.73 ? 245 ILE A N   1 
ATOM   1757  C CA  . ILE A 1 245 ? 135.190 97.665  71.203  1.00 75.73 ? 245 ILE A CA  1 
ATOM   1758  C C   . ILE A 1 245 ? 133.976 97.286  70.379  1.00 75.73 ? 245 ILE A C   1 
ATOM   1759  O O   . ILE A 1 245 ? 133.417 96.198  70.534  1.00 75.73 ? 245 ILE A O   1 
ATOM   1760  C CB  . ILE A 1 245 ? 134.804 98.590  72.369  1.00 75.73 ? 245 ILE A CB  1 
ATOM   1761  C CG1 . ILE A 1 245 ? 136.033 99.005  73.163  1.00 75.73 ? 245 ILE A CG1 1 
ATOM   1762  C CG2 . ILE A 1 245 ? 133.833 97.900  73.290  1.00 75.73 ? 245 ILE A CG2 1 
ATOM   1763  C CD1 . ILE A 1 245 ? 135.708 99.942  74.301  1.00 75.73 ? 245 ILE A CD1 1 
ATOM   1764  N N   . LYS A 1 246 ? 133.547 98.180  69.493  1.00 76.38 ? 246 LYS A N   1 
ATOM   1765  C CA  . LYS A 1 246 ? 132.394 97.894  68.652  1.00 76.38 ? 246 LYS A CA  1 
ATOM   1766  C C   . LYS A 1 246 ? 132.695 96.754  67.686  1.00 76.38 ? 246 LYS A C   1 
ATOM   1767  O O   . LYS A 1 246 ? 131.878 95.841  67.511  1.00 76.38 ? 246 LYS A O   1 
ATOM   1768  C CB  . LYS A 1 246 ? 131.994 99.162  67.903  1.00 76.38 ? 246 LYS A CB  1 
ATOM   1769  C CG  . LYS A 1 246 ? 130.529 99.278  67.575  1.00 76.38 ? 246 LYS A CG  1 
ATOM   1770  C CD  . LYS A 1 246 ? 130.275 100.538 66.779  1.00 76.38 ? 246 LYS A CD  1 
ATOM   1771  C CE  . LYS A 1 246 ? 128.955 100.468 66.042  1.00 76.38 ? 246 LYS A CE  1 
ATOM   1772  N NZ  . LYS A 1 246 ? 128.837 101.564 65.045  1.00 76.38 ? 246 LYS A NZ  1 
ATOM   1773  N N   . GLU A 1 247 ? 133.879 96.786  67.072  1.00 79.39 ? 247 GLU A N   1 
ATOM   1774  C CA  . GLU A 1 247 ? 134.284 95.730  66.151  1.00 79.39 ? 247 GLU A CA  1 
ATOM   1775  C C   . GLU A 1 247 ? 134.249 94.369  66.824  1.00 79.39 ? 247 GLU A C   1 
ATOM   1776  O O   . GLU A 1 247 ? 133.863 93.372  66.206  1.00 79.39 ? 247 GLU A O   1 
ATOM   1777  C CB  . GLU A 1 247 ? 135.686 96.017  65.624  1.00 79.39 ? 247 GLU A CB  1 
ATOM   1778  C CG  . GLU A 1 247 ? 135.837 97.372  64.970  1.00 79.39 ? 247 GLU A CG  1 
ATOM   1779  C CD  . GLU A 1 247 ? 137.282 97.814  64.890  1.00 79.39 ? 247 GLU A CD  1 
ATOM   1780  O OE1 . GLU A 1 247 ? 138.151 97.105  65.436  1.00 79.39 ? 247 GLU A OE1 1 
ATOM   1781  O OE2 . GLU A 1 247 ? 137.551 98.876  64.295  1.00 79.39 ? 247 GLU A OE2 1 
ATOM   1782  N N   . PHE A 1 248 ? 134.654 94.301  68.090  1.00 78.47 ? 248 PHE A N   1 
ATOM   1783  C CA  . PHE A 1 248 ? 134.659 93.002  68.751  1.00 78.47 ? 248 PHE A CA  1 
ATOM   1784  C C   . PHE A 1 248 ? 133.284 92.612  69.273  1.00 78.47 ? 248 PHE A C   1 
ATOM   1785  O O   . PHE A 1 248 ? 132.844 91.478  69.068  1.00 78.47 ? 248 PHE A O   1 
ATOM   1786  C CB  . PHE A 1 248 ? 135.653 92.972  69.902  1.00 78.47 ? 248 PHE A CB  1 
ATOM   1787  C CG  . PHE A 1 248 ? 135.532 91.739  70.746  1.00 78.47 ? 248 PHE A CG  1 
ATOM   1788  C CD1 . PHE A 1 248 ? 135.917 90.511  70.248  1.00 78.47 ? 248 PHE A CD1 1 
ATOM   1789  C CD2 . PHE A 1 248 ? 135.000 91.800  72.018  1.00 78.47 ? 248 PHE A CD2 1 
ATOM   1790  C CE1 . PHE A 1 248 ? 135.811 89.384  71.014  1.00 78.47 ? 248 PHE A CE1 1 
ATOM   1791  C CE2 . PHE A 1 248 ? 134.884 90.669  72.783  1.00 78.47 ? 248 PHE A CE2 1 
ATOM   1792  C CZ  . PHE A 1 248 ? 135.289 89.461  72.281  1.00 78.47 ? 248 PHE A CZ  1 
ATOM   1793  N N   . MET A 1 249 ? 132.604 93.510  69.973  1.00 77.11 ? 249 MET A N   1 
ATOM   1794  C CA  . MET A 1 249 ? 131.312 93.168  70.540  1.00 77.11 ? 249 MET A CA  1 
ATOM   1795  C C   . MET A 1 249 ? 130.237 92.988  69.486  1.00 77.11 ? 249 MET A C   1 
ATOM   1796  O O   . MET A 1 249 ? 129.145 92.521  69.818  1.00 77.11 ? 249 MET A O   1 
ATOM   1797  C CB  . MET A 1 249 ? 130.874 94.239  71.534  1.00 77.11 ? 249 MET A CB  1 
ATOM   1798  C CG  . MET A 1 249 ? 131.635 94.226  72.840  1.00 77.11 ? 249 MET A CG  1 
ATOM   1799  S SD  . MET A 1 249 ? 131.184 95.611  73.898  1.00 77.11 ? 249 MET A SD  1 
ATOM   1800  C CE  . MET A 1 249 ? 129.422 95.358  74.087  1.00 77.11 ? 249 MET A CE  1 
ATOM   1801  N N   . SER A 1 250 ? 130.511 93.347  68.232  1.00 80.90 ? 250 SER A N   1 
ATOM   1802  C CA  . SER A 1 250 ? 129.513 93.190  67.186  1.00 80.90 ? 250 SER A CA  1 
ATOM   1803  C C   . SER A 1 250 ? 129.537 91.810  66.544  1.00 80.90 ? 250 SER A C   1 
ATOM   1804  O O   . SER A 1 250 ? 128.617 91.481  65.790  1.00 80.90 ? 250 SER A O   1 
ATOM   1805  C CB  . SER A 1 250 ? 129.708 94.262  66.116  1.00 80.90 ? 250 SER A CB  1 
ATOM   1806  O OG  . SER A 1 250 ? 129.466 95.549  66.655  1.00 80.90 ? 250 SER A OG  1 
ATOM   1807  N N   . GLU A 1 251 ? 130.546 90.995  66.840  1.00 83.66 ? 251 GLU A N   1 
ATOM   1808  C CA  . GLU A 1 251 ? 130.680 89.689  66.212  1.00 83.66 ? 251 GLU A CA  1 
ATOM   1809  C C   . GLU A 1 251 ? 129.608 88.725  66.720  1.00 83.66 ? 251 GLU A C   1 
ATOM   1810  O O   . GLU A 1 251 ? 128.691 89.091  67.459  1.00 83.66 ? 251 GLU A O   1 
ATOM   1811  C CB  . GLU A 1 251 ? 132.059 89.103  66.483  1.00 83.66 ? 251 GLU A CB  1 
ATOM   1812  C CG  . GLU A 1 251 ? 133.187 90.054  66.211  1.00 83.66 ? 251 GLU A CG  1 
ATOM   1813  C CD  . GLU A 1 251 ? 134.375 89.809  67.110  1.00 83.66 ? 251 GLU A CD  1 
ATOM   1814  O OE1 . GLU A 1 251 ? 134.267 88.971  68.028  1.00 83.66 ? 251 GLU A OE1 1 
ATOM   1815  O OE2 . GLU A 1 251 ? 135.414 90.465  66.907  1.00 83.66 ? 251 GLU A OE2 1 
ATOM   1816  N N   . GLU A 1 252 ? 129.737 87.469  66.299  1.00 88.00 ? 252 GLU A N   1 
ATOM   1817  C CA  . GLU A 1 252 ? 128.802 86.420  66.675  1.00 88.00 ? 252 GLU A CA  1 
ATOM   1818  C C   . GLU A 1 252 ? 129.405 85.367  67.590  1.00 88.00 ? 252 GLU A C   1 
ATOM   1819  O O   . GLU A 1 252 ? 128.710 84.871  68.477  1.00 88.00 ? 252 GLU A O   1 
ATOM   1820  C CB  . GLU A 1 252 ? 128.250 85.744  65.415  1.00 88.00 ? 252 GLU A CB  1 
ATOM   1821  C CG  . GLU A 1 252 ? 129.255 84.875  64.678  1.00 88.00 ? 252 GLU A CG  1 
ATOM   1822  C CD  . GLU A 1 252 ? 130.213 85.670  63.813  1.00 88.00 ? 252 GLU A CD  1 
ATOM   1823  O OE1 . GLU A 1 252 ? 130.315 86.902  63.992  1.00 88.00 ? 252 GLU A OE1 1 
ATOM   1824  O OE2 . GLU A 1 252 ? 130.874 85.057  62.951  1.00 88.00 ? 252 GLU A OE2 1 
ATOM   1825  N N   . LYS A 1 253 ? 130.683 85.022  67.412  1.00 88.61 ? 253 LYS A N   1 
ATOM   1826  C CA  . LYS A 1 253 ? 131.324 84.081  68.323  1.00 88.61 ? 253 LYS A CA  1 
ATOM   1827  C C   . LYS A 1 253 ? 131.430 84.677  69.718  1.00 88.61 ? 253 LYS A C   1 
ATOM   1828  O O   . LYS A 1 253 ? 131.336 83.962  70.722  1.00 88.61 ? 253 LYS A O   1 
ATOM   1829  C CB  . LYS A 1 253 ? 132.703 83.687  67.789  1.00 88.61 ? 253 LYS A CB  1 
ATOM   1830  C CG  . LYS A 1 253 ? 133.243 82.395  68.371  1.00 88.61 ? 253 LYS A CG  1 
ATOM   1831  C CD  . LYS A 1 253 ? 134.689 82.168  67.970  1.00 88.61 ? 253 LYS A CD  1 
ATOM   1832  C CE  . LYS A 1 253 ? 135.611 83.167  68.647  1.00 88.61 ? 253 LYS A CE  1 
ATOM   1833  N NZ  . LYS A 1 253 ? 135.685 82.960  70.118  1.00 88.61 ? 253 LYS A NZ  1 
ATOM   1834  N N   . THR A 1 254 ? 131.631 85.990  69.800  1.00 84.50 ? 254 THR A N   1 
ATOM   1835  C CA  . THR A 1 254 ? 131.486 86.676  71.076  1.00 84.50 ? 254 THR A CA  1 
ATOM   1836  C C   . THR A 1 254 ? 130.057 86.573  71.579  1.00 84.50 ? 254 THR A C   1 
ATOM   1837  O O   . THR A 1 254 ? 129.808 86.121  72.701  1.00 84.50 ? 254 THR A O   1 
ATOM   1838  C CB  . THR A 1 254 ? 131.882 88.139  70.926  1.00 84.50 ? 254 THR A CB  1 
ATOM   1839  O OG1 . THR A 1 254 ? 133.185 88.217  70.342  1.00 84.50 ? 254 THR A OG1 1 
ATOM   1840  C CG2 . THR A 1 254 ? 131.884 88.821  72.272  1.00 84.50 ? 254 THR A CG2 1 
ATOM   1841  N N   . HIS A 1 255 ? 129.099 86.962  70.743  1.00 83.57 ? 255 HIS A N   1 
ATOM   1842  C CA  . HIS A 1 255 ? 127.722 87.094  71.185  1.00 83.57 ? 255 HIS A CA  1 
ATOM   1843  C C   . HIS A 1 255 ? 127.076 85.766  71.545  1.00 83.57 ? 255 HIS A C   1 
ATOM   1844  O O   . HIS A 1 255 ? 125.988 85.769  72.129  1.00 83.57 ? 255 HIS A O   1 
ATOM   1845  C CB  . HIS A 1 255 ? 126.899 87.793  70.109  1.00 83.57 ? 255 HIS A CB  1 
ATOM   1846  C CG  . HIS A 1 255 ? 125.638 88.399  70.629  1.00 83.57 ? 255 HIS A CG  1 
ATOM   1847  N ND1 . HIS A 1 255 ? 124.635 87.646  71.200  1.00 83.57 ? 255 HIS A ND1 1 
ATOM   1848  C CD2 . HIS A 1 255 ? 125.220 89.685  70.682  1.00 83.57 ? 255 HIS A CD2 1 
ATOM   1849  C CE1 . HIS A 1 255 ? 123.649 88.441  71.574  1.00 83.57 ? 255 HIS A CE1 1 
ATOM   1850  N NE2 . HIS A 1 255 ? 123.979 89.684  71.270  1.00 83.57 ? 255 HIS A NE2 1 
ATOM   1851  N N   . GLU A 1 256 ? 127.702 84.638  71.213  1.00 87.01 ? 256 GLU A N   1 
ATOM   1852  C CA  . GLU A 1 256 ? 127.125 83.357  71.605  1.00 87.01 ? 256 GLU A CA  1 
ATOM   1853  C C   . GLU A 1 256 ? 127.450 83.002  73.050  1.00 87.01 ? 256 GLU A C   1 
ATOM   1854  O O   . GLU A 1 256 ? 126.649 82.335  73.712  1.00 87.01 ? 256 GLU A O   1 
ATOM   1855  C CB  . GLU A 1 256 ? 127.609 82.242  70.677  1.00 87.01 ? 256 GLU A CB  1 
ATOM   1856  C CG  . GLU A 1 256 ? 129.074 81.894  70.831  1.00 87.01 ? 256 GLU A CG  1 
ATOM   1857  C CD  . GLU A 1 256 ? 129.541 80.851  69.836  1.00 87.01 ? 256 GLU A CD  1 
ATOM   1858  O OE1 . GLU A 1 256 ? 128.726 80.417  68.997  1.00 87.01 ? 256 GLU A OE1 1 
ATOM   1859  O OE2 . GLU A 1 256 ? 130.725 80.461  69.896  1.00 87.01 ? 256 GLU A OE2 1 
ATOM   1860  N N   . THR A 1 257 ? 128.605 83.437  73.555  1.00 84.79 ? 257 THR A N   1 
ATOM   1861  C CA  . THR A 1 257 ? 129.060 83.084  74.893  1.00 84.79 ? 257 THR A CA  1 
ATOM   1862  C C   . THR A 1 257 ? 128.728 84.147  75.934  1.00 84.79 ? 257 THR A C   1 
ATOM   1863  O O   . THR A 1 257 ? 128.326 83.808  77.048  1.00 84.79 ? 257 THR A O   1 
ATOM   1864  C CB  . THR A 1 257 ? 130.568 82.791  74.874  1.00 84.79 ? 257 THR A CB  1 
ATOM   1865  O OG1 . THR A 1 257 ? 131.010 82.446  76.191  1.00 84.79 ? 257 THR A OG1 1 
ATOM   1866  C CG2 . THR A 1 257 ? 131.361 83.973  74.352  1.00 84.79 ? 257 THR A CG2 1 
ATOM   1867  N N   . MET A 1 258 ? 128.869 85.425  75.596  1.00 81.97 ? 258 MET A N   1 
ATOM   1868  C CA  . MET A 1 258 ? 128.585 86.477  76.560  1.00 81.97 ? 258 MET A CA  1 
ATOM   1869  C C   . MET A 1 258 ? 127.105 86.811  76.579  1.00 81.97 ? 258 MET A C   1 
ATOM   1870  O O   . MET A 1 258 ? 126.394 86.639  75.591  1.00 81.97 ? 258 MET A O   1 
ATOM   1871  C CB  . MET A 1 258 ? 129.385 87.733  76.240  1.00 81.97 ? 258 MET A CB  1 
ATOM   1872  C CG  . MET A 1 258 ? 129.153 88.297  74.859  1.00 81.97 ? 258 MET A CG  1 
ATOM   1873  S SD  . MET A 1 258 ? 127.764 89.421  74.699  1.00 81.97 ? 258 MET A SD  1 
ATOM   1874  C CE  . MET A 1 258 ? 128.470 90.888  75.435  1.00 81.97 ? 258 MET A CE  1 
ATOM   1875  N N   . MET A 1 259 ? 126.641 87.299  77.716  1.00 79.69 ? 259 MET A N   1 
ATOM   1876  C CA  . MET A 1 259 ? 125.283 87.814  77.815  1.00 79.69 ? 259 MET A CA  1 
ATOM   1877  C C   . MET A 1 259 ? 125.387 89.309  77.590  1.00 79.69 ? 259 MET A C   1 
ATOM   1878  O O   . MET A 1 259 ? 125.975 90.023  78.407  1.00 79.69 ? 259 MET A O   1 
ATOM   1879  C CB  . MET A 1 259 ? 124.641 87.509  79.163  1.00 79.69 ? 259 MET A CB  1 
ATOM   1880  C CG  . MET A 1 259 ? 123.178 87.915  79.229  1.00 79.69 ? 259 MET A CG  1 
ATOM   1881  S SD  . MET A 1 259 ? 122.432 87.559  80.828  1.00 79.69 ? 259 MET A SD  1 
ATOM   1882  C CE  . MET A 1 259 ? 122.433 85.771  80.812  1.00 79.69 ? 259 MET A CE  1 
ATOM   1883  N N   . VAL A 1 260 ? 124.836 89.779  76.473  1.00 76.48 ? 260 VAL A N   1 
ATOM   1884  C CA  . VAL A 1 260 ? 125.031 91.174  76.124  1.00 76.48 ? 260 VAL A CA  1 
ATOM   1885  C C   . VAL A 1 260 ? 124.130 92.084  76.942  1.00 76.48 ? 260 VAL A C   1 
ATOM   1886  O O   . VAL A 1 260 ? 124.420 93.276  77.079  1.00 76.48 ? 260 VAL A O   1 
ATOM   1887  C CB  . VAL A 1 260 ? 124.819 91.369  74.613  1.00 76.48 ? 260 VAL A CB  1 
ATOM   1888  C CG1 . VAL A 1 260 ? 123.366 91.204  74.254  1.00 76.48 ? 260 VAL A CG1 1 
ATOM   1889  C CG2 . VAL A 1 260 ? 125.365 92.709  74.159  1.00 76.48 ? 260 VAL A CG2 1 
ATOM   1890  N N   . ASP A 1 261 ? 123.067 91.554  77.529  1.00 76.27 ? 261 ASP A N   1 
ATOM   1891  C CA  . ASP A 1 261 ? 122.129 92.401  78.242  1.00 76.27 ? 261 ASP A CA  1 
ATOM   1892  C C   . ASP A 1 261 ? 122.545 92.713  79.670  1.00 76.27 ? 261 ASP A C   1 
ATOM   1893  O O   . ASP A 1 261 ? 121.885 93.528  80.316  1.00 76.27 ? 261 ASP A O   1 
ATOM   1894  C CB  . ASP A 1 261 ? 120.748 91.762  78.226  1.00 76.27 ? 261 ASP A CB  1 
ATOM   1895  C CG  . ASP A 1 261 ? 120.114 91.816  76.861  1.00 76.27 ? 261 ASP A CG  1 
ATOM   1896  O OD1 . ASP A 1 261 ? 120.847 92.041  75.876  1.00 76.27 ? 261 ASP A OD1 1 
ATOM   1897  O OD2 . ASP A 1 261 ? 118.879 91.655  76.777  1.00 76.27 ? 261 ASP A OD2 1 
ATOM   1898  N N   . ARG A 1 262 ? 123.602 92.101  80.188  1.00 74.99 ? 262 ARG A N   1 
ATOM   1899  C CA  . ARG A 1 262 ? 124.167 92.537  81.462  1.00 74.99 ? 262 ARG A CA  1 
ATOM   1900  C C   . ARG A 1 262 ? 125.342 93.464  81.173  1.00 74.99 ? 262 ARG A C   1 
ATOM   1901  O O   . ARG A 1 262 ? 126.493 93.194  81.508  1.00 74.99 ? 262 ARG A O   1 
ATOM   1902  C CB  . ARG A 1 262 ? 124.584 91.341  82.312  1.00 74.99 ? 262 ARG A CB  1 
ATOM   1903  C CG  . ARG A 1 262 ? 123.469 90.367  82.637  1.00 74.99 ? 262 ARG A CG  1 
ATOM   1904  C CD  . ARG A 1 262 ? 122.527 90.900  83.701  1.00 74.99 ? 262 ARG A CD  1 
ATOM   1905  N NE  . ARG A 1 262 ? 121.428 91.662  83.114  1.00 74.99 ? 262 ARG A NE  1 
ATOM   1906  C CZ  . ARG A 1 262 ? 120.368 92.098  83.789  1.00 74.99 ? 262 ARG A CZ  1 
ATOM   1907  N NH1 . ARG A 1 262 ? 120.252 91.853  85.087  1.00 74.99 ? 262 ARG A NH1 1 
ATOM   1908  N NH2 . ARG A 1 262 ? 119.422 92.784  83.166  1.00 74.99 ? 262 ARG A NH2 1 
ATOM   1909  N N   . SER A 1 263 ? 125.020 94.580  80.529  1.00 67.49 ? 263 SER A N   1 
ATOM   1910  C CA  . SER A 1 263 ? 126.036 95.509  80.070  1.00 67.49 ? 263 SER A CA  1 
ATOM   1911  C C   . SER A 1 263 ? 125.676 96.928  80.476  1.00 67.49 ? 263 SER A C   1 
ATOM   1912  O O   . SER A 1 263 ? 124.500 97.299  80.522  1.00 67.49 ? 263 SER A O   1 
ATOM   1913  C CB  . SER A 1 263 ? 126.208 95.434  78.553  1.00 67.49 ? 263 SER A CB  1 
ATOM   1914  O OG  . SER A 1 263 ? 126.287 94.089  78.127  1.00 67.49 ? 263 SER A OG  1 
ATOM   1915  N N   . TYR A 1 264 ? 126.701 97.721  80.771  1.00 61.34 ? 264 TYR A N   1 
ATOM   1916  C CA  . TYR A 1 264 ? 126.501 99.144  80.970  1.00 61.34 ? 264 TYR A CA  1 
ATOM   1917  C C   . TYR A 1 264 ? 127.743 99.883  80.508  1.00 61.34 ? 264 TYR A C   1 
ATOM   1918  O O   . TYR A 1 264 ? 128.766 99.280  80.191  1.00 61.34 ? 264 TYR A O   1 
ATOM   1919  C CB  . TYR A 1 264 ? 126.172 99.499  82.428  1.00 61.34 ? 264 TYR A CB  1 
ATOM   1920  C CG  . TYR A 1 264 ? 127.226 99.229  83.489  1.00 61.34 ? 264 TYR A CG  1 
ATOM   1921  C CD1 . TYR A 1 264 ? 128.355 100.028 83.598  1.00 61.34 ? 264 TYR A CD1 1 
ATOM   1922  C CD2 . TYR A 1 264 ? 127.089 98.185  84.384  1.00 61.34 ? 264 TYR A CD2 1 
ATOM   1923  C CE1 . TYR A 1 264 ? 129.306 99.796  84.559  1.00 61.34 ? 264 TYR A CE1 1 
ATOM   1924  C CE2 . TYR A 1 264 ? 128.031 97.964  85.361  1.00 61.34 ? 264 TYR A CE2 1 
ATOM   1925  C CZ  . TYR A 1 264 ? 129.142 98.764  85.433  1.00 61.34 ? 264 TYR A CZ  1 
ATOM   1926  O OH  . TYR A 1 264 ? 130.096 98.543  86.395  1.00 61.34 ? 264 TYR A OH  1 
ATOM   1927  N N   . LEU A 1 265 ? 127.643 101.206 80.474  1.00 60.38 ? 265 LEU A N   1 
ATOM   1928  C CA  . LEU A 1 265 ? 128.815 102.054 80.323  1.00 60.38 ? 265 LEU A CA  1 
ATOM   1929  C C   . LEU A 1 265 ? 128.793 103.099 81.420  1.00 60.38 ? 265 LEU A C   1 
ATOM   1930  O O   . LEU A 1 265 ? 127.720 103.504 81.871  1.00 60.38 ? 265 LEU A O   1 
ATOM   1931  C CB  . LEU A 1 265 ? 128.884 102.732 78.957  1.00 60.38 ? 265 LEU A CB  1 
ATOM   1932  C CG  . LEU A 1 265 ? 127.963 103.879 78.555  1.00 60.38 ? 265 LEU A CG  1 
ATOM   1933  C CD1 . LEU A 1 265 ? 128.558 105.222 78.933  1.00 60.38 ? 265 LEU A CD1 1 
ATOM   1934  C CD2 . LEU A 1 265 ? 127.734 103.840 77.070  1.00 60.38 ? 265 LEU A CD2 1 
ATOM   1935  N N   . SER A 1 266 ? 129.967 103.550 81.834  1.00 59.93 ? 266 SER A N   1 
ATOM   1936  C CA  . SER A 1 266 ? 130.078 104.351 83.037  1.00 59.93 ? 266 SER A CA  1 
ATOM   1937  C C   . SER A 1 266 ? 130.984 105.549 82.804  1.00 59.93 ? 266 SER A C   1 
ATOM   1938  O O   . SER A 1 266 ? 131.698 105.635 81.804  1.00 59.93 ? 266 SER A O   1 
ATOM   1939  C CB  . SER A 1 266 ? 130.595 103.503 84.196  1.00 59.93 ? 266 SER A CB  1 
ATOM   1940  O OG  . SER A 1 266 ? 131.882 102.993 83.911  1.00 59.93 ? 266 SER A OG  1 
ATOM   1941  N N   . PHE A 1 267 ? 130.940 106.475 83.756  1.00 52.81 ? 267 PHE A N   1 
ATOM   1942  C CA  . PHE A 1 267 ? 131.656 107.735 83.645  1.00 52.81 ? 267 PHE A CA  1 
ATOM   1943  C C   . PHE A 1 267 ? 131.687 108.393 85.012  1.00 52.81 ? 267 PHE A C   1 
ATOM   1944  O O   . PHE A 1 267 ? 130.844 108.125 85.873  1.00 52.81 ? 267 PHE A O   1 
ATOM   1945  C CB  . PHE A 1 267 ? 130.992 108.670 82.635  1.00 52.81 ? 267 PHE A CB  1 
ATOM   1946  C CG  . PHE A 1 267 ? 129.592 109.044 83.005  1.00 52.81 ? 267 PHE A CG  1 
ATOM   1947  C CD1 . PHE A 1 267 ? 128.533 108.284 82.584  1.00 52.81 ? 267 PHE A CD1 1 
ATOM   1948  C CD2 . PHE A 1 267 ? 129.339 110.142 83.794  1.00 52.81 ? 267 PHE A CD2 1 
ATOM   1949  C CE1 . PHE A 1 267 ? 127.261 108.614 82.931  1.00 52.81 ? 267 PHE A CE1 1 
ATOM   1950  C CE2 . PHE A 1 267 ? 128.063 110.468 84.143  1.00 52.81 ? 267 PHE A CE2 1 
ATOM   1951  C CZ  . PHE A 1 267 ? 127.022 109.703 83.709  1.00 52.81 ? 267 PHE A CZ  1 
ATOM   1952  N N   . ASP A 1 268 ? 132.641 109.293 85.184  1.00 56.90 ? 268 ASP A N   1 
ATOM   1953  C CA  . ASP A 1 268 ? 132.802 110.024 86.427  1.00 56.90 ? 268 ASP A CA  1 
ATOM   1954  C C   . ASP A 1 268 ? 132.145 111.391 86.319  1.00 56.90 ? 268 ASP A C   1 
ATOM   1955  O O   . ASP A 1 268 ? 132.340 112.108 85.334  1.00 56.90 ? 268 ASP A O   1 
ATOM   1956  C CB  . ASP A 1 268 ? 134.279 110.183 86.748  1.00 56.90 ? 268 ASP A CB  1 
ATOM   1957  C CG  . ASP A 1 268 ? 134.974 108.865 86.875  1.00 56.90 ? 268 ASP A CG  1 
ATOM   1958  O OD1 . ASP A 1 268 ? 134.310 107.879 87.232  1.00 56.90 ? 268 ASP A OD1 1 
ATOM   1959  O OD2 . ASP A 1 268 ? 136.183 108.808 86.602  1.00 56.90 ? 268 ASP A OD2 1 
ATOM   1960  N N   . CYS A 1 269 ? 131.374 111.754 87.342  1.00 55.34 ? 269 CYS A N   1 
ATOM   1961  C CA  . CYS A 1 269 ? 130.782 113.086 87.428  1.00 55.34 ? 269 CYS A CA  1 
ATOM   1962  C C   . CYS A 1 269 ? 131.878 114.064 87.825  1.00 55.34 ? 269 CYS A C   1 
ATOM   1963  O O   . CYS A 1 269 ? 132.070 114.387 88.994  1.00 55.34 ? 269 CYS A O   1 
ATOM   1964  C CB  . CYS A 1 269 ? 129.625 113.098 88.415  1.00 55.34 ? 269 CYS A CB  1 
ATOM   1965  S SG  . CYS A 1 269 ? 128.303 111.967 87.974  1.00 55.34 ? 269 CYS A SG  1 
ATOM   1966  N N   . LEU A 1 270 ? 132.614 114.534 86.825  1.00 61.42 ? 270 LEU A N   1 
ATOM   1967  C CA  . LEU A 1 270 ? 133.770 115.386 87.037  1.00 61.42 ? 270 LEU A CA  1 
ATOM   1968  C C   . LEU A 1 270 ? 133.935 116.284 85.822  1.00 61.42 ? 270 LEU A C   1 
ATOM   1969  O O   . LEU A 1 270 ? 133.040 116.393 84.981  1.00 61.42 ? 270 LEU A O   1 
ATOM   1970  C CB  . LEU A 1 270 ? 135.026 114.545 87.279  1.00 61.42 ? 270 LEU A CB  1 
ATOM   1971  C CG  . LEU A 1 270 ? 135.294 114.053 88.696  1.00 61.42 ? 270 LEU A CG  1 
ATOM   1972  C CD1 . LEU A 1 270 ? 136.621 113.330 88.741  1.00 61.42 ? 270 LEU A CD1 1 
ATOM   1973  C CD2 . LEU A 1 270 ? 135.281 115.213 89.665  1.00 61.42 ? 270 LEU A CD2 1 
ATOM   1974  N N   . ASP A 1 271 ? 135.085 116.935 85.739  1.00 68.11 ? 271 ASP A N   1 
ATOM   1975  C CA  . ASP A 1 271 ? 135.458 117.715 84.570  1.00 68.11 ? 271 ASP A CA  1 
ATOM   1976  C C   . ASP A 1 271 ? 135.616 116.770 83.389  1.00 68.11 ? 271 ASP A C   1 
ATOM   1977  O O   . ASP A 1 271 ? 136.566 115.980 83.358  1.00 68.11 ? 271 ASP A O   1 
ATOM   1978  C CB  . ASP A 1 271 ? 136.754 118.481 84.832  1.00 68.11 ? 271 ASP A CB  1 
ATOM   1979  C CG  . ASP A 1 271 ? 137.011 119.561 83.806  1.00 68.11 ? 271 ASP A CG  1 
ATOM   1980  O OD1 . ASP A 1 271 ? 136.290 119.606 82.791  1.00 68.11 ? 271 ASP A OD1 1 
ATOM   1981  O OD2 . ASP A 1 271 ? 137.936 120.371 84.015  1.00 68.11 ? 271 ASP A OD2 1 
ATOM   1982  N N   . PRO A 1 272 ? 134.719 116.819 82.401  1.00 68.78 ? 272 PRO A N   1 
ATOM   1983  C CA  . PRO A 1 272 ? 134.766 115.830 81.315  1.00 68.78 ? 272 PRO A CA  1 
ATOM   1984  C C   . PRO A 1 272 ? 136.087 115.793 80.589  1.00 68.78 ? 272 PRO A C   1 
ATOM   1985  O O   . PRO A 1 272 ? 136.322 114.853 79.826  1.00 68.78 ? 272 PRO A O   1 
ATOM   1986  C CB  . PRO A 1 272 ? 133.628 116.265 80.385  1.00 68.78 ? 272 PRO A CB  1 
ATOM   1987  C CG  . PRO A 1 272 ? 133.335 117.652 80.758  1.00 68.78 ? 272 PRO A CG  1 
ATOM   1988  C CD  . PRO A 1 272 ? 133.630 117.784 82.210  1.00 68.78 ? 272 PRO A CD  1 
ATOM   1989  N N   . ALA A 1 273 ? 136.959 116.773 80.806  1.00 71.05 ? 273 ALA A N   1 
ATOM   1990  C CA  . ALA A 1 273 ? 138.339 116.639 80.369  1.00 71.05 ? 273 ALA A CA  1 
ATOM   1991  C C   . ALA A 1 273 ? 139.136 115.715 81.281  1.00 71.05 ? 273 ALA A C   1 
ATOM   1992  O O   . ALA A 1 273 ? 140.299 115.424 80.987  1.00 71.05 ? 273 ALA A O   1 
ATOM   1993  C CB  . ALA A 1 273 ? 139.001 118.013 80.298  1.00 71.05 ? 273 ALA A CB  1 
ATOM   1994  N N   . LYS A 1 274 ? 138.540 115.248 82.377  1.00 70.65 ? 274 LYS A N   1 
ATOM   1995  C CA  . LYS A 1 274 ? 139.218 114.344 83.291  1.00 70.65 ? 274 LYS A CA  1 
ATOM   1996  C C   . LYS A 1 274 ? 138.522 113.000 83.433  1.00 70.65 ? 274 LYS A C   1 
ATOM   1997  O O   . LYS A 1 274 ? 139.165 112.029 83.844  1.00 70.65 ? 274 LYS A O   1 
ATOM   1998  C CB  . LYS A 1 274 ? 139.337 114.987 84.675  1.00 70.65 ? 274 LYS A CB  1 
ATOM   1999  C CG  . LYS A 1 274 ? 139.917 116.378 84.654  1.00 70.65 ? 274 LYS A CG  1 
ATOM   2000  C CD  . LYS A 1 274 ? 141.346 116.356 84.164  1.00 70.65 ? 274 LYS A CD  1 
ATOM   2001  C CE  . LYS A 1 274 ? 141.885 117.761 83.975  1.00 70.65 ? 274 LYS A CE  1 
ATOM   2002  N NZ  . LYS A 1 274 ? 141.304 118.424 82.777  1.00 70.65 ? 274 LYS A NZ  1 
ATOM   2003  N N   . SER A 1 275 ? 137.235 112.920 83.106  1.00 67.15 ? 275 SER A N   1 
ATOM   2004  C CA  . SER A 1 275 ? 136.493 111.681 83.266  1.00 67.15 ? 275 SER A CA  1 
ATOM   2005  C C   . SER A 1 275 ? 136.943 110.647 82.235  1.00 67.15 ? 275 SER A C   1 
ATOM   2006  O O   . SER A 1 275 ? 137.794 110.897 81.377  1.00 67.15 ? 275 SER A O   1 
ATOM   2007  C CB  . SER A 1 275 ? 134.998 111.939 83.142  1.00 67.15 ? 275 SER A CB  1 
ATOM   2008  O OG  . SER A 1 275 ? 134.537 112.806 84.156  1.00 67.15 ? 275 SER A OG  1 
ATOM   2009  N N   . ARG A 1 276 ? 136.355 109.462 82.334  1.00 65.70 ? 276 ARG A N   1 
ATOM   2010  C CA  . ARG A 1 276 ? 136.614 108.358 81.428  1.00 65.70 ? 276 ARG A CA  1 
ATOM   2011  C C   . ARG A 1 276 ? 135.279 107.770 81.007  1.00 65.70 ? 276 ARG A C   1 
ATOM   2012  O O   . ARG A 1 276 ? 134.231 108.114 81.556  1.00 65.70 ? 276 ARG A O   1 
ATOM   2013  C CB  . ARG A 1 276 ? 137.494 107.292 82.092  1.00 65.70 ? 276 ARG A CB  1 
ATOM   2014  C CG  . ARG A 1 276 ? 138.877 107.787 82.481  1.00 65.70 ? 276 ARG A CG  1 
ATOM   2015  C CD  . ARG A 1 276 ? 138.910 108.314 83.903  1.00 65.70 ? 276 ARG A CD  1 
ATOM   2016  N NE  . ARG A 1 276 ? 138.533 107.313 84.896  1.00 65.70 ? 276 ARG A NE  1 
ATOM   2017  C CZ  . ARG A 1 276 ? 139.388 106.498 85.506  1.00 65.70 ? 276 ARG A CZ  1 
ATOM   2018  N NH1 . ARG A 1 276 ? 140.681 106.556 85.224  1.00 65.70 ? 276 ARG A NH1 1 
ATOM   2019  N NH2 . ARG A 1 276 ? 138.945 105.620 86.396  1.00 65.70 ? 276 ARG A NH2 1 
ATOM   2020  N N   . ILE A 1 277 ? 135.304 106.878 80.024  1.00 66.69 ? 277 ILE A N   1 
ATOM   2021  C CA  . ILE A 1 277 ? 134.097 106.150 79.652  1.00 66.69 ? 277 ILE A CA  1 
ATOM   2022  C C   . ILE A 1 277 ? 134.432 104.668 79.646  1.00 66.69 ? 277 ILE A C   1 
ATOM   2023  O O   . ILE A 1 277 ? 135.231 104.215 78.823  1.00 66.69 ? 277 ILE A O   1 
ATOM   2024  C CB  . ILE A 1 277 ? 133.540 106.590 78.291  1.00 66.69 ? 277 ILE A CB  1 
ATOM   2025  C CG1 . ILE A 1 277 ? 133.077 108.041 78.339  1.00 66.69 ? 277 ILE A CG1 1 
ATOM   2026  C CG2 . ILE A 1 277 ? 132.357 105.725 77.907  1.00 66.69 ? 277 ILE A CG2 1 
ATOM   2027  C CD1 . ILE A 1 277 ? 131.693 108.200 78.869  1.00 66.69 ? 277 ILE A CD1 1 
ATOM   2028  N N   . LYS A 1 278 ? 133.838 103.921 80.569  1.00 65.42 ? 278 LYS A N   1 
ATOM   2029  C CA  . LYS A 1 278 ? 134.063 102.490 80.688  1.00 65.42 ? 278 LYS A CA  1 
ATOM   2030  C C   . LYS A 1 278 ? 132.839 101.752 80.181  1.00 65.42 ? 278 LYS A C   1 
ATOM   2031  O O   . LYS A 1 278 ? 131.727 102.029 80.629  1.00 65.42 ? 278 LYS A O   1 
ATOM   2032  C CB  . LYS A 1 278 ? 134.336 102.092 82.138  1.00 65.42 ? 278 LYS A CB  1 
ATOM   2033  C CG  . LYS A 1 278 ? 135.417 102.896 82.822  1.00 65.42 ? 278 LYS A CG  1 
ATOM   2034  C CD  . LYS A 1 278 ? 135.795 102.306 84.174  1.00 65.42 ? 278 LYS A CD  1 
ATOM   2035  C CE  . LYS A 1 278 ? 134.666 102.415 85.187  1.00 65.42 ? 278 LYS A CE  1 
ATOM   2036  N NZ  . LYS A 1 278 ? 135.045 101.817 86.496  1.00 65.42 ? 278 LYS A NZ  1 
ATOM   2037  N N   . ILE A 1 279 ? 133.045 100.824 79.255  1.00 66.55 ? 279 ILE A N   1 
ATOM   2038  C CA  . ILE A 1 279 ? 132.022 99.867  78.854  1.00 66.55 ? 279 ILE A CA  1 
ATOM   2039  C C   . ILE A 1 279 ? 132.203 98.615  79.698  1.00 66.55 ? 279 ILE A C   1 
ATOM   2040  O O   . ILE A 1 279 ? 133.293 98.340  80.197  1.00 66.55 ? 279 ILE A O   1 
ATOM   2041  C CB  . ILE A 1 279 ? 132.086 99.542  77.348  1.00 66.55 ? 279 ILE A CB  1 
ATOM   2042  C CG1 . ILE A 1 279 ? 132.299 100.809 76.524  1.00 66.55 ? 279 ILE A CG1 1 
ATOM   2043  C CG2 . ILE A 1 279 ? 130.797 98.903  76.902  1.00 66.55 ? 279 ILE A CG2 1 
ATOM   2044  C CD1 . ILE A 1 279 ? 131.074 101.679 76.419  1.00 66.55 ? 279 ILE A CD1 1 
ATOM   2045  N N   . TYR A 1 280 ? 131.131 97.844  79.854  1.00 67.91 ? 280 TYR A N   1 
ATOM   2046  C CA  . TYR A 1 280 ? 131.076 96.785  80.851  1.00 67.91 ? 280 TYR A CA  1 
ATOM   2047  C C   . TYR A 1 280 ? 130.095 95.711  80.411  1.00 67.91 ? 280 TYR A C   1 
ATOM   2048  O O   . TYR A 1 280 ? 128.962 96.042  80.060  1.00 67.91 ? 280 TYR A O   1 
ATOM   2049  C CB  . TYR A 1 280 ? 130.621 97.358  82.184  1.00 67.91 ? 280 TYR A CB  1 
ATOM   2050  C CG  . TYR A 1 280 ? 130.432 96.328  83.251  1.00 67.91 ? 280 TYR A CG  1 
ATOM   2051  C CD1 . TYR A 1 280 ? 131.484 95.935  84.055  1.00 67.91 ? 280 TYR A CD1 1 
ATOM   2052  C CD2 . TYR A 1 280 ? 129.207 95.708  83.421  1.00 67.91 ? 280 TYR A CD2 1 
ATOM   2053  C CE1 . TYR A 1 280 ? 131.306 94.985  85.029  1.00 67.91 ? 280 TYR A CE1 1 
ATOM   2054  C CE2 . TYR A 1 280 ? 129.020 94.763  84.383  1.00 67.91 ? 280 TYR A CE2 1 
ATOM   2055  C CZ  . TYR A 1 280 ? 130.069 94.401  85.181  1.00 67.91 ? 280 TYR A CZ  1 
ATOM   2056  O OH  . TYR A 1 280 ? 129.865 93.445  86.137  1.00 67.91 ? 280 TYR A OH  1 
ATOM   2057  N N   . THR A 1 281 ? 130.500 94.439  80.471  1.00 71.32 ? 281 THR A N   1 
ATOM   2058  C CA  . THR A 1 281 ? 129.603 93.336  80.126  1.00 71.32 ? 281 THR A CA  1 
ATOM   2059  C C   . THR A 1 281 ? 130.048 92.068  80.858  1.00 71.32 ? 281 THR A C   1 
ATOM   2060  O O   . THR A 1 281 ? 130.982 92.093  81.662  1.00 71.32 ? 281 THR A O   1 
ATOM   2061  C CB  . THR A 1 281 ? 129.535 93.148  78.607  1.00 71.32 ? 281 THR A CB  1 
ATOM   2062  O OG1 . THR A 1 281 ? 128.346 92.428  78.265  1.00 71.32 ? 281 THR A OG1 1 
ATOM   2063  C CG2 . THR A 1 281 ? 130.734 92.393  78.111  1.00 71.32 ? 281 THR A CG2 1 
ATOM   2064  N N   . GLU A 1 282 ? 129.352 90.951  80.587  1.00 75.81 ? 282 GLU A N   1 
ATOM   2065  C CA  . GLU A 1 282 ? 129.458 89.723  81.374  1.00 75.81 ? 282 GLU A CA  1 
ATOM   2066  C C   . GLU A 1 282 ? 129.479 88.483  80.488  1.00 75.81 ? 282 GLU A C   1 
ATOM   2067  O O   . GLU A 1 282 ? 128.752 88.409  79.490  1.00 75.81 ? 282 GLU A O   1 
ATOM   2068  C CB  . GLU A 1 282 ? 128.290 89.601  82.364  1.00 75.81 ? 282 GLU A CB  1 
ATOM   2069  C CG  . GLU A 1 282 ? 128.319 90.615  83.492  1.00 75.81 ? 282 GLU A CG  1 
ATOM   2070  C CD  . GLU A 1 282 ? 127.249 90.361  84.531  1.00 75.81 ? 282 GLU A CD  1 
ATOM   2071  O OE1 . GLU A 1 282 ? 126.394 89.484  84.303  1.00 75.81 ? 282 GLU A OE1 1 
ATOM   2072  O OE2 . GLU A 1 282 ? 127.263 91.038  85.578  1.00 75.81 ? 282 GLU A OE2 1 
ATOM   2073  N N   . ALA A 1 283 ? 130.283 87.491  80.884  1.00 77.92 ? 283 ALA A N   1 
ATOM   2074  C CA  . ALA A 1 283 ? 130.478 86.283  80.094  1.00 77.92 ? 283 ALA A CA  1 
ATOM   2075  C C   . ALA A 1 283 ? 130.439 85.041  80.975  1.00 77.92 ? 283 ALA A C   1 
ATOM   2076  O O   . ALA A 1 283 ? 130.838 85.069  82.144  1.00 77.92 ? 283 ALA A O   1 
ATOM   2077  C CB  . ALA A 1 283 ? 131.807 86.315  79.337  1.00 77.92 ? 283 ALA A CB  1 
ATOM   2078  N N   . LYS A 1 284 ? 129.950 83.946  80.393  1.00 78.72 ? 284 LYS A N   1 
ATOM   2079  C CA  . LYS A 1 284 ? 129.945 82.616  81.003  1.00 78.72 ? 284 LYS A CA  1 
ATOM   2080  C C   . LYS A 1 284 ? 130.879 81.759  80.163  1.00 78.72 ? 284 LYS A C   1 
ATOM   2081  O O   . LYS A 1 284 ? 130.460 81.191  79.153  1.00 78.72 ? 284 LYS A O   1 
ATOM   2082  C CB  . LYS A 1 284 ? 128.547 82.017  81.033  1.00 78.72 ? 284 LYS A CB  1 
ATOM   2083  C CG  . LYS A 1 284 ? 127.733 82.364  82.250  1.00 78.72 ? 284 LYS A CG  1 
ATOM   2084  C CD  . LYS A 1 284 ? 126.299 81.929  82.060  1.00 78.72 ? 284 LYS A CD  1 
ATOM   2085  C CE  . LYS A 1 284 ? 125.426 82.427  83.187  1.00 78.72 ? 284 LYS A CE  1 
ATOM   2086  N NZ  . LYS A 1 284 ? 124.015 82.566  82.748  1.00 78.72 ? 284 LYS A NZ  1 
ATOM   2087  N N   . VAL A 1 285 ? 132.132 81.653  80.574  1.00 81.98 ? 285 VAL A N   1 
ATOM   2088  C CA  . VAL A 1 285 ? 133.160 81.085  79.716  1.00 81.98 ? 285 VAL A CA  1 
ATOM   2089  C C   . VAL A 1 285 ? 133.600 79.728  80.240  1.00 81.98 ? 285 VAL A C   1 
ATOM   2090  O O   . VAL A 1 285 ? 133.564 79.450  81.442  1.00 81.98 ? 285 VAL A O   1 
ATOM   2091  C CB  . VAL A 1 285 ? 134.363 82.034  79.578  1.00 81.98 ? 285 VAL A CB  1 
ATOM   2092  C CG1 . VAL A 1 285 ? 133.916 83.337  78.964  1.00 81.98 ? 285 VAL A CG1 1 
ATOM   2093  C CG2 . VAL A 1 285 ? 135.006 82.274  80.923  1.00 81.98 ? 285 VAL A CG2 1 
ATOM   2094  N N   . LYS A 1 286 ? 134.031 78.881  79.311  1.00 81.90 ? 286 LYS A N   1 
ATOM   2095  C CA  . LYS A 1 286 ? 134.437 77.512  79.591  1.00 81.90 ? 286 LYS A CA  1 
ATOM   2096  C C   . LYS A 1 286 ? 135.915 77.376  79.910  1.00 81.90 ? 286 LYS A C   1 
ATOM   2097  O O   . LYS A 1 286 ? 136.271 76.797  80.938  1.00 81.90 ? 286 LYS A O   1 
ATOM   2098  C CB  . LYS A 1 286 ? 134.104 76.619  78.397  1.00 81.90 ? 286 LYS A CB  1 
ATOM   2099  C CG  . LYS A 1 286 ? 134.583 75.201  78.548  1.00 81.90 ? 286 LYS A CG  1 
ATOM   2100  C CD  . LYS A 1 286 ? 133.842 74.486  79.656  1.00 81.90 ? 286 LYS A CD  1 
ATOM   2101  C CE  . LYS A 1 286 ? 134.237 73.023  79.704  1.00 81.90 ? 286 LYS A CE  1 
ATOM   2102  N NZ  . LYS A 1 286 ? 135.670 72.854  80.076  1.00 81.90 ? 286 LYS A NZ  1 
ATOM   2103  N N   . THR A 1 287 ? 136.785 77.885  79.052  1.00 83.99 ? 287 THR A N   1 
ATOM   2104  C CA  . THR A 1 287 ? 138.218 77.837  79.276  1.00 83.99 ? 287 THR A CA  1 
ATOM   2105  C C   . THR A 1 287 ? 138.744 79.249  79.473  1.00 83.99 ? 287 THR A C   1 
ATOM   2106  O O   . THR A 1 287 ? 138.109 80.226  79.071  1.00 83.99 ? 287 THR A O   1 
ATOM   2107  C CB  . THR A 1 287 ? 138.952 77.180  78.103  1.00 83.99 ? 287 THR A CB  1 
ATOM   2108  O OG1 . THR A 1 287 ? 139.179 78.153  77.076  1.00 83.99 ? 287 THR A OG1 1 
ATOM   2109  C CG2 . THR A 1 287 ? 138.126 76.046  77.531  1.00 83.99 ? 287 THR A CG2 1 
ATOM   2110  N N   . LEU A 1 288 ? 139.908 79.354  80.111  1.00 84.50 ? 288 LEU A N   1 
ATOM   2111  C CA  . LEU A 1 288 ? 140.546 80.659  80.215  1.00 84.50 ? 288 LEU A CA  1 
ATOM   2112  C C   . LEU A 1 288 ? 141.006 81.139  78.846  1.00 84.50 ? 288 LEU A C   1 
ATOM   2113  O O   . LEU A 1 288 ? 140.935 82.337  78.541  1.00 84.50 ? 288 LEU A O   1 
ATOM   2114  C CB  . LEU A 1 288 ? 141.709 80.599  81.204  1.00 84.50 ? 288 LEU A CB  1 
ATOM   2115  C CG  . LEU A 1 288 ? 142.959 79.803  80.840  1.00 84.50 ? 288 LEU A CG  1 
ATOM   2116  C CD1 . LEU A 1 288 ? 144.007 80.710  80.233  1.00 84.50 ? 288 LEU A CD1 1 
ATOM   2117  C CD2 . LEU A 1 288 ? 143.506 79.099  82.060  1.00 84.50 ? 288 LEU A CD2 1 
ATOM   2118  N N   . GLU A 1 289 ? 141.468 80.214  78.007  1.00 86.02 ? 289 GLU A N   1 
ATOM   2119  C CA  . GLU A 1 289 ? 141.824 80.563  76.640  1.00 86.02 ? 289 GLU A CA  1 
ATOM   2120  C C   . GLU A 1 289 ? 140.679 81.294  75.953  1.00 86.02 ? 289 GLU A C   1 
ATOM   2121  O O   . GLU A 1 289 ? 140.860 82.389  75.409  1.00 86.02 ? 289 GLU A O   1 
ATOM   2122  C CB  . GLU A 1 289 ? 142.203 79.301  75.866  1.00 86.02 ? 289 GLU A CB  1 
ATOM   2123  C CG  . GLU A 1 289 ? 142.258 79.486  74.361  1.00 86.02 ? 289 GLU A CG  1 
ATOM   2124  C CD  . GLU A 1 289 ? 140.917 79.255  73.694  1.00 86.02 ? 289 GLU A CD  1 
ATOM   2125  O OE1 . GLU A 1 289 ? 140.042 78.627  74.324  1.00 86.02 ? 289 GLU A OE1 1 
ATOM   2126  O OE2 . GLU A 1 289 ? 140.734 79.713  72.550  1.00 86.02 ? 289 GLU A OE2 1 
ATOM   2127  N N   . GLU A 1 290 ? 139.483 80.705  75.982  1.00 85.09 ? 290 GLU A N   1 
ATOM   2128  C CA  . GLU A 1 290 ? 138.353 81.314  75.295  1.00 85.09 ? 290 GLU A CA  1 
ATOM   2129  C C   . GLU A 1 290 ? 137.960 82.622  75.955  1.00 85.09 ? 290 GLU A C   1 
ATOM   2130  O O   . GLU A 1 290 ? 137.317 83.470  75.331  1.00 85.09 ? 290 GLU A O   1 
ATOM   2131  C CB  . GLU A 1 290 ? 137.165 80.360  75.271  1.00 85.09 ? 290 GLU A CB  1 
ATOM   2132  C CG  . GLU A 1 290 ? 136.188 80.569  76.404  1.00 85.09 ? 290 GLU A CG  1 
ATOM   2133  C CD  . GLU A 1 290 ? 135.106 79.517  76.427  1.00 85.09 ? 290 GLU A CD  1 
ATOM   2134  O OE1 . GLU A 1 290 ? 135.294 78.463  75.787  1.00 85.09 ? 290 GLU A OE1 1 
ATOM   2135  O OE2 . GLU A 1 290 ? 134.064 79.746  77.073  1.00 85.09 ? 290 GLU A OE2 1 
ATOM   2136  N N   . ALA A 1 291 ? 138.329 82.802  77.223  1.00 83.66 ? 291 ALA A N   1 
ATOM   2137  C CA  . ALA A 1 291 ? 138.058 84.062  77.899  1.00 83.66 ? 291 ALA A CA  1 
ATOM   2138  C C   . ALA A 1 291 ? 139.029 85.154  77.493  1.00 83.66 ? 291 ALA A C   1 
ATOM   2139  O O   . ALA A 1 291 ? 138.685 86.333  77.598  1.00 83.66 ? 291 ALA A O   1 
ATOM   2140  C CB  . ALA A 1 291 ? 138.098 83.881  79.416  1.00 83.66 ? 291 ALA A CB  1 
ATOM   2141  N N   . TYR A 1 292 ? 140.224 84.791  77.024  1.00 82.12 ? 292 TYR A N   1 
ATOM   2142  C CA  . TYR A 1 292 ? 141.194 85.795  76.596  1.00 82.12 ? 292 TYR A CA  1 
ATOM   2143  C C   . TYR A 1 292 ? 140.612 86.783  75.598  1.00 82.12 ? 292 TYR A C   1 
ATOM   2144  O O   . TYR A 1 292 ? 141.134 87.896  75.463  1.00 82.12 ? 292 TYR A O   1 
ATOM   2145  C CB  . TYR A 1 292 ? 142.410 85.113  75.981  1.00 82.12 ? 292 TYR A CB  1 
ATOM   2146  C CG  . TYR A 1 292 ? 143.533 86.059  75.648  1.00 82.12 ? 292 TYR A CG  1 
ATOM   2147  C CD1 . TYR A 1 292 ? 143.849 87.113  76.489  1.00 82.12 ? 292 TYR A CD1 1 
ATOM   2148  C CD2 . TYR A 1 292 ? 144.286 85.892  74.495  1.00 82.12 ? 292 TYR A CD2 1 
ATOM   2149  C CE1 . TYR A 1 292 ? 144.878 87.976  76.189  1.00 82.12 ? 292 TYR A CE1 1 
ATOM   2150  C CE2 . TYR A 1 292 ? 145.317 86.750  74.188  1.00 82.12 ? 292 TYR A CE2 1 
ATOM   2151  C CZ  . TYR A 1 292 ? 145.609 87.789  75.039  1.00 82.12 ? 292 TYR A CZ  1 
ATOM   2152  O OH  . TYR A 1 292 ? 146.637 88.646  74.738  1.00 82.12 ? 292 TYR A OH  1 
ATOM   2153  N N   . SER A 1 293 ? 139.538 86.410  74.907  1.00 79.53 ? 293 SER A N   1 
ATOM   2154  C CA  . SER A 1 293 ? 138.935 87.314  73.936  1.00 79.53 ? 293 SER A CA  1 
ATOM   2155  C C   . SER A 1 293 ? 138.454 88.595  74.605  1.00 79.53 ? 293 SER A C   1 
ATOM   2156  O O   . SER A 1 293 ? 138.847 89.698  74.210  1.00 79.53 ? 293 SER A O   1 
ATOM   2157  C CB  . SER A 1 293 ? 137.787 86.611  73.215  1.00 79.53 ? 293 SER A CB  1 
ATOM   2158  O OG  . SER A 1 293 ? 136.598 86.664  73.979  1.00 79.53 ? 293 SER A OG  1 
ATOM   2159  N N   . PHE A 1 294 ? 137.611 88.468  75.632  1.00 78.22 ? 294 PHE A N   1 
ATOM   2160  C CA  . PHE A 1 294 ? 137.058 89.644  76.299  1.00 78.22 ? 294 PHE A CA  1 
ATOM   2161  C C   . PHE A 1 294 ? 138.153 90.543  76.843  1.00 78.22 ? 294 PHE A C   1 
ATOM   2162  O O   . PHE A 1 294 ? 138.062 91.770  76.754  1.00 78.22 ? 294 PHE A O   1 
ATOM   2163  C CB  . PHE A 1 294 ? 136.130 89.218  77.426  1.00 78.22 ? 294 PHE A CB  1 
ATOM   2164  C CG  . PHE A 1 294 ? 134.912 88.524  76.954  1.00 78.22 ? 294 PHE A CG  1 
ATOM   2165  C CD1 . PHE A 1 294 ? 134.974 87.213  76.533  1.00 78.22 ? 294 PHE A CD1 1 
ATOM   2166  C CD2 . PHE A 1 294 ? 133.707 89.181  76.918  1.00 78.22 ? 294 PHE A CD2 1 
ATOM   2167  C CE1 . PHE A 1 294 ? 133.858 86.573  76.089  1.00 78.22 ? 294 PHE A CE1 1 
ATOM   2168  C CE2 . PHE A 1 294 ? 132.590 88.547  76.478  1.00 78.22 ? 294 PHE A CE2 1 
ATOM   2169  C CZ  . PHE A 1 294 ? 132.664 87.239  76.061  1.00 78.22 ? 294 PHE A CZ  1 
ATOM   2170  N N   . TRP A 1 295 ? 139.188 89.950  77.426  1.00 76.49 ? 295 TRP A N   1 
ATOM   2171  C CA  . TRP A 1 295 ? 140.342 90.732  77.833  1.00 76.49 ? 295 TRP A CA  1 
ATOM   2172  C C   . TRP A 1 295 ? 140.976 91.446  76.651  1.00 76.49 ? 295 TRP A C   1 
ATOM   2173  O O   . TRP A 1 295 ? 141.506 92.550  76.808  1.00 76.49 ? 295 TRP A O   1 
ATOM   2174  C CB  . TRP A 1 295 ? 141.365 89.826  78.499  1.00 76.49 ? 295 TRP A CB  1 
ATOM   2175  C CG  . TRP A 1 295 ? 142.474 90.557  79.114  1.00 76.49 ? 295 TRP A CG  1 
ATOM   2176  C CD1 . TRP A 1 295 ? 143.717 90.734  78.607  1.00 76.49 ? 295 TRP A CD1 1 
ATOM   2177  C CD2 . TRP A 1 295 ? 142.451 91.215  80.370  1.00 76.49 ? 295 TRP A CD2 1 
ATOM   2178  N NE1 . TRP A 1 295 ? 144.478 91.468  79.470  1.00 76.49 ? 295 TRP A NE1 1 
ATOM   2179  C CE2 . TRP A 1 295 ? 143.719 91.775  80.567  1.00 76.49 ? 295 TRP A CE2 1 
ATOM   2180  C CE3 . TRP A 1 295 ? 141.476 91.386  81.353  1.00 76.49 ? 295 TRP A CE3 1 
ATOM   2181  C CZ2 . TRP A 1 295 ? 144.039 92.497  81.705  1.00 76.49 ? 295 TRP A CZ2 1 
ATOM   2182  C CZ3 . TRP A 1 295 ? 141.793 92.097  82.476  1.00 76.49 ? 295 TRP A CZ3 1 
ATOM   2183  C CH2 . TRP A 1 295 ? 143.062 92.645  82.646  1.00 76.49 ? 295 TRP A CH2 1 
ATOM   2184  N N   . SER A 1 296 ? 140.932 90.841  75.465  1.00 79.37 ? 296 SER A N   1 
ATOM   2185  C CA  . SER A 1 296 ? 141.669 91.344  74.316  1.00 79.37 ? 296 SER A CA  1 
ATOM   2186  C C   . SER A 1 296 ? 140.777 91.870  73.202  1.00 79.37 ? 296 SER A C   1 
ATOM   2187  O O   . SER A 1 296 ? 141.296 92.288  72.163  1.00 79.37 ? 296 SER A O   1 
ATOM   2188  C CB  . SER A 1 296 ? 142.576 90.245  73.767  1.00 79.37 ? 296 SER A CB  1 
ATOM   2189  O OG  . SER A 1 296 ? 141.812 89.100  73.440  1.00 79.37 ? 296 SER A OG  1 
ATOM   2190  N N   . LEU A 1 297 ? 139.458 91.868  73.386  1.00 77.71 ? 297 LEU A N   1 
ATOM   2191  C CA  . LEU A 1 297 ? 138.527 92.275  72.333  1.00 77.71 ? 297 LEU A CA  1 
ATOM   2192  C C   . LEU A 1 297 ? 138.754 91.470  71.059  1.00 77.71 ? 297 LEU A C   1 
ATOM   2193  O O   . LEU A 1 297 ? 138.657 91.987  69.947  1.00 77.71 ? 297 LEU A O   1 
ATOM   2194  C CB  . LEU A 1 297 ? 138.628 93.769  72.039  1.00 77.71 ? 297 LEU A CB  1 
ATOM   2195  C CG  . LEU A 1 297 ? 138.194 94.725  73.136  1.00 77.71 ? 297 LEU A CG  1 
ATOM   2196  C CD1 . LEU A 1 297 ? 138.265 96.121  72.608  1.00 77.71 ? 297 LEU A CD1 1 
ATOM   2197  C CD2 . LEU A 1 297 ? 136.793 94.406  73.565  1.00 77.71 ? 297 LEU A CD2 1 
ATOM   2198  N N   . GLY A 1 298 ? 139.053 90.187  71.218  1.00 80.20 ? 298 GLY A N   1 
ATOM   2199  C CA  . GLY A 1 298 ? 139.287 89.325  70.083  1.00 80.20 ? 298 GLY A CA  1 
ATOM   2200  C C   . GLY A 1 298 ? 140.627 89.503  69.416  1.00 80.20 ? 298 GLY A C   1 
ATOM   2201  O O   . GLY A 1 298 ? 140.749 89.203  68.223  1.00 80.20 ? 298 GLY A O   1 
ATOM   2202  N N   . GLY A 1 299 ? 141.632 89.981  70.136  1.00 81.25 ? 299 GLY A N   1 
ATOM   2203  C CA  . GLY A 1 299 ? 142.939 90.213  69.571  1.00 81.25 ? 299 GLY A CA  1 
ATOM   2204  C C   . GLY A 1 299 ? 143.183 91.635  69.125  1.00 81.25 ? 299 GLY A C   1 
ATOM   2205  O O   . GLY A 1 299 ? 144.345 92.032  68.985  1.00 81.25 ? 299 GLY A O   1 
ATOM   2206  N N   . ARG A 1 300 ? 142.125 92.414  68.905  1.00 80.50 ? 300 ARG A N   1 
ATOM   2207  C CA  . ARG A 1 300 ? 142.311 93.800  68.497  1.00 80.50 ? 300 ARG A CA  1 
ATOM   2208  C C   . ARG A 1 300 ? 143.024 94.598  69.576  1.00 80.50 ? 300 ARG A C   1 
ATOM   2209  O O   . ARG A 1 300 ? 144.023 95.272  69.303  1.00 80.50 ? 300 ARG A O   1 
ATOM   2210  C CB  . ARG A 1 300 ? 140.963 94.430  68.165  1.00 80.50 ? 300 ARG A CB  1 
ATOM   2211  C CG  . ARG A 1 300 ? 140.215 93.696  67.085  1.00 80.50 ? 300 ARG A CG  1 
ATOM   2212  C CD  . ARG A 1 300 ? 138.726 93.807  67.266  1.00 80.50 ? 300 ARG A CD  1 
ATOM   2213  N NE  . ARG A 1 300 ? 138.012 93.306  66.096  1.00 80.50 ? 300 ARG A NE  1 
ATOM   2214  C CZ  . ARG A 1 300 ? 137.673 92.036  65.915  1.00 80.50 ? 300 ARG A CZ  1 
ATOM   2215  N NH1 . ARG A 1 300 ? 137.976 91.131  66.831  1.00 80.50 ? 300 ARG A NH1 1 
ATOM   2216  N NH2 . ARG A 1 300 ? 137.024 91.670  64.820  1.00 80.50 ? 300 ARG A NH2 1 
ATOM   2217  N N   . LEU A 1 301 ? 142.539 94.518  70.810  1.00 81.43 ? 301 LEU A N   1 
ATOM   2218  C CA  . LEU A 1 301 ? 143.077 95.300  71.917  1.00 81.43 ? 301 LEU A CA  1 
ATOM   2219  C C   . LEU A 1 301 ? 144.253 94.518  72.484  1.00 81.43 ? 301 LEU A C   1 
ATOM   2220  O O   . LEU A 1 301 ? 144.072 93.627  73.314  1.00 81.43 ? 301 LEU A O   1 
ATOM   2221  C CB  . LEU A 1 301 ? 142.009 95.538  72.976  1.00 81.43 ? 301 LEU A CB  1 
ATOM   2222  C CG  . LEU A 1 301 ? 142.190 96.758  73.878  1.00 81.43 ? 301 LEU A CG  1 
ATOM   2223  C CD1 . LEU A 1 301 ? 140.912 97.037  74.636  1.00 81.43 ? 301 LEU A CD1 1 
ATOM   2224  C CD2 . LEU A 1 301 ? 143.358 96.630  74.816  1.00 81.43 ? 301 LEU A CD2 1 
ATOM   2225  N N   . SER A 1 302 ? 145.461 94.857  72.047  1.00 84.48 ? 302 SER A N   1 
ATOM   2226  C CA  . SER A 1 302 ? 146.633 94.085  72.423  1.00 84.48 ? 302 SER A CA  1 
ATOM   2227  C C   . SER A 1 302 ? 147.784 95.023  72.747  1.00 84.48 ? 302 SER A C   1 
ATOM   2228  O O   . SER A 1 302 ? 147.926 96.089  72.143  1.00 84.48 ? 302 SER A O   1 
ATOM   2229  C CB  . SER A 1 302 ? 147.033 93.121  71.306  1.00 84.48 ? 302 SER A CB  1 
ATOM   2230  O OG  . SER A 1 302 ? 145.904 92.411  70.837  1.00 84.48 ? 302 SER A OG  1 
ATOM   2231  N N   . GLY A 1 303 ? 148.608 94.611  73.707  1.00 93.15 ? 303 GLY A N   1 
ATOM   2232  C CA  . GLY A 1 303 ? 149.754 95.387  74.113  1.00 93.15 ? 303 GLY A CA  1 
ATOM   2233  C C   . GLY A 1 303 ? 150.684 94.613  75.025  1.00 93.15 ? 303 GLY A C   1 
ATOM   2234  O O   . GLY A 1 303 ? 150.474 93.429  75.303  1.00 93.15 ? 303 GLY A O   1 
ATOM   2235  N N   . PRO A 1 304 ? 151.753 95.264  75.489  1.00 95.20 ? 304 PRO A N   1 
ATOM   2236  C CA  . PRO A 1 304 ? 152.620 94.610  76.482  1.00 95.20 ? 304 PRO A CA  1 
ATOM   2237  C C   . PRO A 1 304 ? 151.918 94.341  77.802  1.00 95.20 ? 304 PRO A C   1 
ATOM   2238  O O   . PRO A 1 304 ? 152.313 93.423  78.530  1.00 95.20 ? 304 PRO A O   1 
ATOM   2239  C CB  . PRO A 1 304 ? 153.780 95.602  76.648  1.00 95.20 ? 304 PRO A CB  1 
ATOM   2240  C CG  . PRO A 1 304 ? 153.754 96.442  75.429  1.00 95.20 ? 304 PRO A CG  1 
ATOM   2241  C CD  . PRO A 1 304 ? 152.325 96.529  75.000  1.00 95.20 ? 304 PRO A CD  1 
ATOM   2242  N N   . GLU A 1 305 ? 150.892 95.121  78.140  1.00 94.12 ? 305 GLU A N   1 
ATOM   2243  C CA  . GLU A 1 305 ? 150.205 94.931  79.412  1.00 94.12 ? 305 GLU A CA  1 
ATOM   2244  C C   . GLU A 1 305 ? 148.961 94.067  79.261  1.00 94.12 ? 305 GLU A C   1 
ATOM   2245  O O   . GLU A 1 305 ? 148.467 93.508  80.249  1.00 94.12 ? 305 GLU A O   1 
ATOM   2246  C CB  . GLU A 1 305 ? 149.846 96.285  80.019  1.00 94.12 ? 305 GLU A CB  1 
ATOM   2247  C CG  . GLU A 1 305 ? 151.041 97.041  80.563  1.00 94.12 ? 305 GLU A CG  1 
ATOM   2248  C CD  . GLU A 1 305 ? 151.722 97.886  79.509  1.00 94.12 ? 305 GLU A CD  1 
ATOM   2249  O OE1 . GLU A 1 305 ? 151.915 97.388  78.382  1.00 94.12 ? 305 GLU A OE1 1 
ATOM   2250  O OE2 . GLU A 1 305 ? 152.070 99.046  79.811  1.00 94.12 ? 305 GLU A OE2 1 
ATOM   2251  N N   . ILE A 1 306 ? 148.442 93.944  78.037  1.00 90.79 ? 306 ILE A N   1 
ATOM   2252  C CA  . ILE A 1 306 ? 147.271 93.107  77.803  1.00 90.79 ? 306 ILE A CA  1 
ATOM   2253  C C   . ILE A 1 306 ? 147.537 91.667  78.207  1.00 90.79 ? 306 ILE A C   1 
ATOM   2254  O O   . ILE A 1 306 ? 146.632 90.975  78.690  1.00 90.79 ? 306 ILE A O   1 
ATOM   2255  C CB  . ILE A 1 306 ? 146.832 93.204  76.333  1.00 90.79 ? 306 ILE A CB  1 
ATOM   2256  C CG1 . ILE A 1 306 ? 146.370 94.622  76.048  1.00 90.79 ? 306 ILE A CG1 1 
ATOM   2257  C CG2 . ILE A 1 306 ? 145.715 92.230  76.048  1.00 90.79 ? 306 ILE A CG2 1 
ATOM   2258  C CD1 . ILE A 1 306 ? 145.419 95.120  77.095  1.00 90.79 ? 306 ILE A CD1 1 
ATOM   2259  N N   . ASP A 1 307 ? 148.773 91.195  78.043  1.00 95.71 ? 307 ASP A N   1 
ATOM   2260  C CA  . ASP A 1 307 ? 149.098 89.832  78.441  1.00 95.71 ? 307 ASP A CA  1 
ATOM   2261  C C   . ASP A 1 307 ? 149.585 89.764  79.883  1.00 95.71 ? 307 ASP A C   1 
ATOM   2262  O O   . ASP A 1 307 ? 149.406 88.737  80.549  1.00 95.71 ? 307 ASP A O   1 
ATOM   2263  C CB  . ASP A 1 307 ? 150.143 89.243  77.495  1.00 95.71 ? 307 ASP A CB  1 
ATOM   2264  C CG  . ASP A 1 307 ? 151.406 90.064  77.449  1.00 95.71 ? 307 ASP A CG  1 
ATOM   2265  O OD1 . ASP A 1 307 ? 152.169 90.030  78.435  1.00 95.71 ? 307 ASP A OD1 1 
ATOM   2266  O OD2 . ASP A 1 307 ? 151.636 90.748  76.431  1.00 95.71 ? 307 ASP A OD2 1 
ATOM   2267  N N   . TYR A 1 308 ? 150.217 90.835  80.376  1.00 93.34 ? 308 TYR A N   1 
ATOM   2268  C CA  . TYR A 1 308 ? 150.583 90.898  81.787  1.00 93.34 ? 308 TYR A CA  1 
ATOM   2269  C C   . TYR A 1 308 ? 149.386 90.594  82.671  1.00 93.34 ? 308 TYR A C   1 
ATOM   2270  O O   . TYR A 1 308 ? 149.437 89.700  83.522  1.00 93.34 ? 308 TYR A O   1 
ATOM   2271  C CB  . TYR A 1 308 ? 151.138 92.276  82.144  1.00 93.34 ? 308 TYR A CB  1 
ATOM   2272  C CG  . TYR A 1 308 ? 152.551 92.519  81.703  1.00 93.34 ? 308 TYR A CG  1 
ATOM   2273  C CD1 . TYR A 1 308 ? 153.231 91.587  80.944  1.00 93.34 ? 308 TYR A CD1 1 
ATOM   2274  C CD2 . TYR A 1 308 ? 153.208 93.687  82.051  1.00 93.34 ? 308 TYR A CD2 1 
ATOM   2275  C CE1 . TYR A 1 308 ? 154.522 91.814  80.536  1.00 93.34 ? 308 TYR A CE1 1 
ATOM   2276  C CE2 . TYR A 1 308 ? 154.498 93.924  81.651  1.00 93.34 ? 308 TYR A CE2 1 
ATOM   2277  C CZ  . TYR A 1 308 ? 155.151 92.984  80.893  1.00 93.34 ? 308 TYR A CZ  1 
ATOM   2278  O OH  . TYR A 1 308 ? 156.444 93.216  80.490  1.00 93.34 ? 308 TYR A OH  1 
ATOM   2279  N N   . GLY A 1 309 ? 148.296 91.335  82.479  1.00 88.53 ? 309 GLY A N   1 
ATOM   2280  C CA  . GLY A 1 309 ? 147.111 91.102  83.285  1.00 88.53 ? 309 GLY A CA  1 
ATOM   2281  C C   . GLY A 1 309 ? 146.494 89.741  83.043  1.00 88.53 ? 309 GLY A C   1 
ATOM   2282  O O   . GLY A 1 309 ? 145.946 89.121  83.965  1.00 88.53 ? 309 GLY A O   1 
ATOM   2283  N N   . PHE A 1 310 ? 146.577 89.248  81.807  1.00 87.38 ? 310 PHE A N   1 
ATOM   2284  C CA  . PHE A 1 310 ? 145.925 87.984  81.496  1.00 87.38 ? 310 PHE A CA  1 
ATOM   2285  C C   . PHE A 1 310 ? 146.625 86.817  82.174  1.00 87.38 ? 310 PHE A C   1 
ATOM   2286  O O   . PHE A 1 310 ? 145.969 85.866  82.615  1.00 87.38 ? 310 PHE A O   1 
ATOM   2287  C CB  . PHE A 1 310 ? 145.872 87.756  79.994  1.00 87.38 ? 310 PHE A CB  1 
ATOM   2288  C CG  . PHE A 1 310 ? 145.315 86.423  79.628  1.00 87.38 ? 310 PHE A CG  1 
ATOM   2289  C CD1 . PHE A 1 310 ? 143.987 86.129  79.880  1.00 87.38 ? 310 PHE A CD1 1 
ATOM   2290  C CD2 . PHE A 1 310 ? 146.118 85.451  79.063  1.00 87.38 ? 310 PHE A CD2 1 
ATOM   2291  C CE1 . PHE A 1 310 ? 143.465 84.900  79.558  1.00 87.38 ? 310 PHE A CE1 1 
ATOM   2292  C CE2 . PHE A 1 310 ? 145.598 84.215  78.739  1.00 87.38 ? 310 PHE A CE2 1 
ATOM   2293  C CZ  . PHE A 1 310 ? 144.271 83.940  78.986  1.00 87.38 ? 310 PHE A CZ  1 
ATOM   2294  N N   . LYS A 1 311 ? 147.954 86.856  82.246  1.00 88.19 ? 311 LYS A N   1 
ATOM   2295  C CA  . LYS A 1 311 ? 148.671 85.810  82.964  1.00 88.19 ? 311 LYS A CA  1 
ATOM   2296  C C   . LYS A 1 311 ? 148.160 85.698  84.387  1.00 88.19 ? 311 LYS A C   1 
ATOM   2297  O O   . LYS A 1 311 ? 147.890 84.599  84.884  1.00 88.19 ? 311 LYS A O   1 
ATOM   2298  C CB  . LYS A 1 311 ? 150.168 86.096  82.968  1.00 88.19 ? 311 LYS A CB  1 
ATOM   2299  C CG  . LYS A 1 311 ? 151.001 84.994  83.611  1.00 88.19 ? 311 LYS A CG  1 
ATOM   2300  C CD  . LYS A 1 311 ? 151.190 85.194  85.110  1.00 88.19 ? 311 LYS A CD  1 
ATOM   2301  C CE  . LYS A 1 311 ? 151.863 86.513  85.422  1.00 88.19 ? 311 LYS A CE  1 
ATOM   2302  N NZ  . LYS A 1 311 ? 152.138 86.628  86.880  1.00 88.19 ? 311 LYS A NZ  1 
ATOM   2303  N N   . ILE A 1 312 ? 148.022 86.837  85.062  1.00 86.31 ? 312 ILE A N   1 
ATOM   2304  C CA  . ILE A 1 312 ? 147.633 86.821  86.464  1.00 86.31 ? 312 ILE A CA  1 
ATOM   2305  C C   . ILE A 1 312 ? 146.196 86.349  86.612  1.00 86.31 ? 312 ILE A C   1 
ATOM   2306  O O   . ILE A 1 312 ? 145.859 85.626  87.561  1.00 86.31 ? 312 ILE A O   1 
ATOM   2307  C CB  . ILE A 1 312 ? 147.843 88.207  87.092  1.00 86.31 ? 312 ILE A CB  1 
ATOM   2308  C CG1 . ILE A 1 312 ? 149.312 88.604  87.008  1.00 86.31 ? 312 ILE A CG1 1 
ATOM   2309  C CG2 . ILE A 1 312 ? 147.416 88.195  88.534  1.00 86.31 ? 312 ILE A CG2 1 
ATOM   2310  C CD1 . ILE A 1 312 ? 149.582 90.033  87.393  1.00 86.31 ? 312 ILE A CD1 1 
ATOM   2311  N N   . VAL A 1 313 ? 145.322 86.741  85.681  1.00 84.46 ? 313 VAL A N   1 
ATOM   2312  C CA  . VAL A 1 313 ? 143.945 86.299  85.851  1.00 84.46 ? 313 VAL A CA  1 
ATOM   2313  C C   . VAL A 1 313 ? 143.820 84.810  85.577  1.00 84.46 ? 313 VAL A C   1 
ATOM   2314  O O   . VAL A 1 313 ? 143.044 84.128  86.243  1.00 84.46 ? 313 VAL A O   1 
ATOM   2315  C CB  . VAL A 1 313 ? 142.952 87.106  85.000  1.00 84.46 ? 313 VAL A CB  1 
ATOM   2316  C CG1 . VAL A 1 313 ? 143.121 86.814  83.530  1.00 84.46 ? 313 VAL A CG1 1 
ATOM   2317  C CG2 . VAL A 1 313 ? 141.531 86.798  85.462  1.00 84.46 ? 313 VAL A CG2 1 
ATOM   2318  N N   . SER A 1 314 ? 144.588 84.263  84.638  1.00 86.62 ? 314 SER A N   1 
ATOM   2319  C CA  . SER A 1 314 ? 144.555 82.816  84.461  1.00 86.62 ? 314 SER A CA  1 
ATOM   2320  C C   . SER A 1 314 ? 145.116 82.115  85.688  1.00 86.62 ? 314 SER A C   1 
ATOM   2321  O O   . SER A 1 314 ? 144.614 81.061  86.103  1.00 86.62 ? 314 SER A O   1 
ATOM   2322  C CB  . SER A 1 314 ? 145.334 82.421  83.212  1.00 86.62 ? 314 SER A CB  1 
ATOM   2323  O OG  . SER A 1 314 ? 146.706 82.234  83.507  1.00 86.62 ? 314 SER A OG  1 
ATOM   2324  N N   . GLN A 1 315 ? 146.152 82.704  86.286  1.00 85.35 ? 315 GLN A N   1 
ATOM   2325  C CA  . GLN A 1 315 ? 146.726 82.177  87.515  1.00 85.35 ? 315 GLN A CA  1 
ATOM   2326  C C   . GLN A 1 315 ? 145.662 82.032  88.595  1.00 85.35 ? 315 GLN A C   1 
ATOM   2327  O O   . GLN A 1 315 ? 145.372 80.923  89.060  1.00 85.35 ? 315 GLN A O   1 
ATOM   2328  C CB  . GLN A 1 315 ? 147.852 83.104  87.969  1.00 85.35 ? 315 GLN A CB  1 
ATOM   2329  C CG  . GLN A 1 315 ? 148.458 82.793  89.315  1.00 85.35 ? 315 GLN A CG  1 
ATOM   2330  C CD  . GLN A 1 315 ? 149.621 83.716  89.627  1.00 85.35 ? 315 GLN A CD  1 
ATOM   2331  O OE1 . GLN A 1 315 ? 150.024 84.522  88.788  1.00 85.35 ? 315 GLN A OE1 1 
ATOM   2332  N NE2 . GLN A 1 315 ? 150.164 83.605  90.832  1.00 85.35 ? 315 GLN A NE2 1 
ATOM   2333  N N   . MET A 1 316 ? 145.045 83.144  88.988  1.00 84.34 ? 316 MET A N   1 
ATOM   2334  C CA  . MET A 1 316 ? 144.054 83.050  90.054  1.00 84.34 ? 316 MET A CA  1 
ATOM   2335  C C   . MET A 1 316 ? 142.818 82.287  89.604  1.00 84.34 ? 316 MET A C   1 
ATOM   2336  O O   . MET A 1 316 ? 142.116 81.702  90.434  1.00 84.34 ? 316 MET A O   1 
ATOM   2337  C CB  . MET A 1 316 ? 143.656 84.427  90.562  1.00 84.34 ? 316 MET A CB  1 
ATOM   2338  C CG  . MET A 1 316 ? 143.115 84.373  91.976  1.00 84.34 ? 316 MET A CG  1 
ATOM   2339  S SD  . MET A 1 316 ? 141.945 85.674  92.361  1.00 84.34 ? 316 MET A SD  1 
ATOM   2340  C CE  . MET A 1 316 ? 140.703 85.392  91.106  1.00 84.34 ? 316 MET A CE  1 
ATOM   2341  N N   . TRP A 1 317 ? 142.548 82.263  88.302  1.00 85.50 ? 317 TRP A N   1 
ATOM   2342  C CA  . TRP A 1 317 ? 141.444 81.485  87.762  1.00 85.50 ? 317 TRP A CA  1 
ATOM   2343  C C   . TRP A 1 317 ? 141.599 80.019  88.119  1.00 85.50 ? 317 TRP A C   1 
ATOM   2344  O O   . TRP A 1 317 ? 140.753 79.439  88.808  1.00 85.50 ? 317 TRP A O   1 
ATOM   2345  C CB  . TRP A 1 317 ? 141.399 81.689  86.245  1.00 85.50 ? 317 TRP A CB  1 
ATOM   2346  C CG  . TRP A 1 317 ? 140.643 80.675  85.442  1.00 85.50 ? 317 TRP A CG  1 
ATOM   2347  C CD1 . TRP A 1 317 ? 140.999 79.381  85.200  1.00 85.50 ? 317 TRP A CD1 1 
ATOM   2348  C CD2 . TRP A 1 317 ? 139.445 80.901  84.702  1.00 85.50 ? 317 TRP A CD2 1 
ATOM   2349  N NE1 . TRP A 1 317 ? 140.075 78.778  84.394  1.00 85.50 ? 317 TRP A NE1 1 
ATOM   2350  C CE2 . TRP A 1 317 ? 139.112 79.693  84.069  1.00 85.50 ? 317 TRP A CE2 1 
ATOM   2351  C CE3 . TRP A 1 317 ? 138.611 82.003  84.527  1.00 85.50 ? 317 TRP A CE3 1 
ATOM   2352  C CZ2 . TRP A 1 317 ? 137.989 79.558  83.273  1.00 85.50 ? 317 TRP A CZ2 1 
ATOM   2353  C CZ3 . TRP A 1 317 ? 137.492 81.864  83.738  1.00 85.50 ? 317 TRP A CZ3 1 
ATOM   2354  C CH2 . TRP A 1 317 ? 137.192 80.652  83.120  1.00 85.50 ? 317 TRP A CH2 1 
ATOM   2355  N N   . ASP A 1 318 ? 142.674 79.395  87.642  1.00 87.93 ? 318 ASP A N   1 
ATOM   2356  C CA  . ASP A 1 318 ? 142.831 77.981  87.943  1.00 87.93 ? 318 ASP A CA  1 
ATOM   2357  C C   . ASP A 1 318 ? 143.079 77.755  89.424  1.00 87.93 ? 318 ASP A C   1 
ATOM   2358  O O   . ASP A 1 318 ? 142.738 76.687  89.939  1.00 87.93 ? 318 ASP A O   1 
ATOM   2359  C CB  . ASP A 1 318 ? 143.928 77.355  87.073  1.00 87.93 ? 318 ASP A CB  1 
ATOM   2360  C CG  . ASP A 1 318 ? 145.331 77.782  87.461  1.00 87.93 ? 318 ASP A CG  1 
ATOM   2361  O OD1 . ASP A 1 318 ? 145.543 78.387  88.531  1.00 87.93 ? 318 ASP A OD1 1 
ATOM   2362  O OD2 . ASP A 1 318 ? 146.252 77.481  86.676  1.00 87.93 ? 318 ASP A OD2 1 
ATOM   2363  N N   . ALA A 1 319 ? 143.626 78.753  90.123  1.00 85.26 ? 319 ALA A N   1 
ATOM   2364  C CA  . ALA A 1 319 ? 143.748 78.657  91.571  1.00 85.26 ? 319 ALA A CA  1 
ATOM   2365  C C   . ALA A 1 319 ? 142.388 78.433  92.226  1.00 85.26 ? 319 ALA A C   1 
ATOM   2366  O O   . ALA A 1 319 ? 142.142 77.386  92.833  1.00 85.26 ? 319 ALA A O   1 
ATOM   2367  C CB  . ALA A 1 319 ? 144.412 79.920  92.119  1.00 85.26 ? 319 ALA A CB  1 
ATOM   2368  N N   . ILE A 1 320 ? 141.480 79.403  92.095  1.00 81.65 ? 320 ILE A N   1 
ATOM   2369  C CA  . ILE A 1 320 ? 140.210 79.320  92.812  1.00 81.65 ? 320 ILE A CA  1 
ATOM   2370  C C   . ILE A 1 320 ? 139.215 78.381  92.158  1.00 81.65 ? 320 ILE A C   1 
ATOM   2371  O O   . ILE A 1 320 ? 138.188 78.067  92.768  1.00 81.65 ? 320 ILE A O   1 
ATOM   2372  C CB  . ILE A 1 320 ? 139.522 80.688  92.960  1.00 81.65 ? 320 ILE A CB  1 
ATOM   2373  C CG1 . ILE A 1 320 ? 138.631 80.695  94.201  1.00 81.65 ? 320 ILE A CG1 1 
ATOM   2374  C CG2 . ILE A 1 320 ? 138.679 80.989  91.739  1.00 81.65 ? 320 ILE A CG2 1 
ATOM   2375  C CD1 . ILE A 1 320 ? 138.185 82.069  94.637  1.00 81.65 ? 320 ILE A CD1 1 
ATOM   2376  N N   . TYR A 1 321 ? 139.473 77.923  90.938  1.00 84.33 ? 321 TYR A N   1 
ATOM   2377  C CA  . TYR A 1 321 ? 138.590 76.952  90.315  1.00 84.33 ? 321 TYR A CA  1 
ATOM   2378  C C   . TYR A 1 321 ? 139.096 75.527  90.447  1.00 84.33 ? 321 TYR A C   1 
ATOM   2379  O O   . TYR A 1 321 ? 138.345 74.590  90.155  1.00 84.33 ? 321 TYR A O   1 
ATOM   2380  C CB  . TYR A 1 321 ? 138.388 77.298  88.841  1.00 84.33 ? 321 TYR A CB  1 
ATOM   2381  C CG  . TYR A 1 321 ? 137.514 78.501  88.658  1.00 84.33 ? 321 TYR A CG  1 
ATOM   2382  C CD1 . TYR A 1 321 ? 136.371 78.654  89.412  1.00 84.33 ? 321 TYR A CD1 1 
ATOM   2383  C CD2 . TYR A 1 321 ? 137.830 79.485  87.739  1.00 84.33 ? 321 TYR A CD2 1 
ATOM   2384  C CE1 . TYR A 1 321 ? 135.563 79.745  89.258  1.00 84.33 ? 321 TYR A CE1 1 
ATOM   2385  C CE2 . TYR A 1 321 ? 137.027 80.586  87.575  1.00 84.33 ? 321 TYR A CE2 1 
ATOM   2386  C CZ  . TYR A 1 321 ? 135.891 80.709  88.340  1.00 84.33 ? 321 TYR A CZ  1 
ATOM   2387  O OH  . TYR A 1 321 ? 135.068 81.799  88.199  1.00 84.33 ? 321 TYR A OH  1 
ATOM   2388  N N   . SER A 1 322 ? 140.342 75.345  90.884  1.00 86.71 ? 322 SER A N   1 
ATOM   2389  C CA  . SER A 1 322 ? 140.827 74.007  91.183  1.00 86.71 ? 322 SER A CA  1 
ATOM   2390  C C   . SER A 1 322 ? 140.033 73.375  92.319  1.00 86.71 ? 322 SER A C   1 
ATOM   2391  O O   . SER A 1 322 ? 139.868 72.152  92.364  1.00 86.71 ? 322 SER A O   1 
ATOM   2392  C CB  . SER A 1 322 ? 142.306 74.074  91.533  1.00 86.71 ? 322 SER A CB  1 
ATOM   2393  O OG  . SER A 1 322 ? 142.503 74.949  92.631  1.00 86.71 ? 322 SER A OG  1 
ATOM   2394  N N   . LYS A 1 323 ? 139.536 74.184  93.247  1.00 86.03 ? 323 LYS A N   1 
ATOM   2395  C CA  . LYS A 1 323 ? 138.757 73.651  94.353  1.00 86.03 ? 323 LYS A CA  1 
ATOM   2396  C C   . LYS A 1 323 ? 137.367 73.243  93.885  1.00 86.03 ? 323 LYS A C   1 
ATOM   2397  O O   . LYS A 1 323 ? 136.932 73.556  92.775  1.00 86.03 ? 323 LYS A O   1 
ATOM   2398  C CB  . LYS A 1 323 ? 138.635 74.675  95.478  1.00 86.03 ? 323 LYS A CB  1 
ATOM   2399  C CG  . LYS A 1 323 ? 139.882 75.488  95.697  1.00 86.03 ? 323 LYS A CG  1 
ATOM   2400  C CD  . LYS A 1 323 ? 141.067 74.608  96.025  1.00 86.03 ? 323 LYS A CD  1 
ATOM   2401  C CE  . LYS A 1 323 ? 142.359 75.398  95.949  1.00 86.03 ? 323 LYS A CE  1 
ATOM   2402  N NZ  . LYS A 1 323 ? 142.500 76.083  94.641  1.00 86.03 ? 323 LYS A NZ  1 
ATOM   2403  N N   . GLU A 1 324 ? 136.671 72.528  94.757  1.00 89.85 ? 324 GLU A N   1 
ATOM   2404  C CA  . GLU A 1 324 ? 135.319 72.081  94.481  1.00 89.85 ? 324 GLU A CA  1 
ATOM   2405  C C   . GLU A 1 324 ? 134.305 73.052  95.069  1.00 89.85 ? 324 GLU A C   1 
ATOM   2406  O O   . GLU A 1 324 ? 134.624 73.909  95.895  1.00 89.85 ? 324 GLU A O   1 
ATOM   2407  C CB  . GLU A 1 324 ? 135.083 70.688  95.056  1.00 89.85 ? 324 GLU A CB  1 
ATOM   2408  C CG  . GLU A 1 324 ? 134.891 70.682  96.556  1.00 89.85 ? 324 GLU A CG  1 
ATOM   2409  C CD  . GLU A 1 324 ? 136.186 70.923  97.298  1.00 89.85 ? 324 GLU A CD  1 
ATOM   2410  O OE1 . GLU A 1 324 ? 137.257 70.765  96.679  1.00 89.85 ? 324 GLU A OE1 1 
ATOM   2411  O OE2 . GLU A 1 324 ? 136.139 71.276  98.495  1.00 89.85 ? 324 GLU A OE2 1 
ATOM   2412  N N   . LEU A 1 325 ? 133.083 72.906  94.635  1.00 87.67 ? 325 LEU A N   1 
ATOM   2413  C CA  . LEU A 1 325 ? 132.016 73.696  95.209  1.00 87.67 ? 325 LEU A CA  1 
ATOM   2414  C C   . LEU A 1 325 ? 131.577 73.078  96.533  1.00 87.67 ? 325 LEU A C   1 
ATOM   2415  O O   . LEU A 1 325 ? 131.705 71.869  96.732  1.00 87.67 ? 325 LEU A O   1 
ATOM   2416  C CB  . LEU A 1 325 ? 130.841 73.764  94.244  1.00 87.67 ? 325 LEU A CB  1 
ATOM   2417  C CG  . LEU A 1 325 ? 129.785 74.846  94.437  1.00 87.67 ? 325 LEU A CG  1 
ATOM   2418  C CD1 . LEU A 1 325 ? 129.314 75.359  93.093  1.00 87.67 ? 325 LEU A CD1 1 
ATOM   2419  C CD2 . LEU A 1 325 ? 128.619 74.306  95.235  1.00 87.67 ? 325 LEU A CD2 1 
ATOM   2420  N N   . PRO A 1 326 ? 131.095 73.890  97.470  1.00 87.73 ? 326 PRO A N   1 
ATOM   2421  C CA  . PRO A 1 326 ? 130.552 73.329  98.711  1.00 87.73 ? 326 PRO A CA  1 
ATOM   2422  C C   . PRO A 1 326 ? 129.394 72.383  98.460  1.00 87.73 ? 326 PRO A C   1 
ATOM   2423  O O   . PRO A 1 326 ? 128.331 72.802  97.993  1.00 87.73 ? 326 PRO A O   1 
ATOM   2424  C CB  . PRO A 1 326 ? 130.097 74.569  99.488  1.00 87.73 ? 326 PRO A CB  1 
ATOM   2425  C CG  . PRO A 1 326 ? 130.968 75.649  98.995  1.00 87.73 ? 326 PRO A CG  1 
ATOM   2426  C CD  . PRO A 1 326 ? 131.264 75.350  97.555  1.00 87.73 ? 326 PRO A CD  1 
ATOM   2427  N N   . GLY A 1 327 ? 129.587 71.110  98.777  1.00 92.28 ? 327 GLY A N   1 
ATOM   2428  C CA  . GLY A 1 327 ? 128.556 70.117  98.590  1.00 92.28 ? 327 GLY A CA  1 
ATOM   2429  C C   . GLY A 1 327 ? 128.671 69.293  97.330  1.00 92.28 ? 327 GLY A C   1 
ATOM   2430  O O   . GLY A 1 327 ? 127.688 68.653  96.941  1.00 92.28 ? 327 GLY A O   1 
ATOM   2431  N N   . GLY A 1 328 ? 129.824 69.303  96.671  1.00 95.82 ? 328 GLY A N   1 
ATOM   2432  C CA  . GLY A 1 328 ? 130.047 68.454  95.523  1.00 95.82 ? 328 GLY A CA  1 
ATOM   2433  C C   . GLY A 1 328 ? 129.290 68.821  94.268  1.00 95.82 ? 328 GLY A C   1 
ATOM   2434  O O   . GLY A 1 328 ? 129.359 68.068  93.291  1.00 95.82 ? 328 GLY A O   1 
ATOM   2435  N N   . LYS A 1 329 ? 128.563 69.936  94.252  1.00 96.18 ? 329 LYS A N   1 
ATOM   2436  C CA  . LYS A 1 329 ? 127.907 70.357  93.022  1.00 96.18 ? 329 LYS A CA  1 
ATOM   2437  C C   . LYS A 1 329 ? 128.953 70.688  91.968  1.00 96.18 ? 329 LYS A C   1 
ATOM   2438  O O   . LYS A 1 329 ? 130.020 71.224  92.275  1.00 96.18 ? 329 LYS A O   1 
ATOM   2439  C CB  . LYS A 1 329 ? 127.005 71.562  93.278  1.00 96.18 ? 329 LYS A CB  1 
ATOM   2440  C CG  . LYS A 1 329 ? 125.737 71.224  94.039  1.00 96.18 ? 329 LYS A CG  1 
ATOM   2441  C CD  . LYS A 1 329 ? 124.711 72.338  93.925  1.00 96.18 ? 329 LYS A CD  1 
ATOM   2442  C CE  . LYS A 1 329 ? 124.427 72.680  92.471  1.00 96.18 ? 329 LYS A CE  1 
ATOM   2443  N NZ  . LYS A 1 329 ? 123.985 71.488  91.697  1.00 96.18 ? 329 LYS A NZ  1 
ATOM   2444  N N   . GLN A 1 330 ? 128.649 70.354  90.720  1.00 95.89 ? 330 GLN A N   1 
ATOM   2445  C CA  . GLN A 1 330 ? 129.646 70.440  89.666  1.00 95.89 ? 330 GLN A CA  1 
ATOM   2446  C C   . GLN A 1 330 ? 129.677 71.828  89.041  1.00 95.89 ? 330 GLN A C   1 
ATOM   2447  O O   . GLN A 1 330 ? 128.648 72.493  88.897  1.00 95.89 ? 330 GLN A O   1 
ATOM   2448  C CB  . GLN A 1 330 ? 129.372 69.391  88.593  1.00 95.89 ? 330 GLN A CB  1 
ATOM   2449  C CG  . GLN A 1 330 ? 129.668 67.986  89.053  1.00 95.89 ? 330 GLN A CG  1 
ATOM   2450  C CD  . GLN A 1 330 ? 130.963 67.906  89.830  1.00 95.89 ? 330 GLN A CD  1 
ATOM   2451  O OE1 . GLN A 1 330 ? 130.967 67.604  91.022  1.00 95.89 ? 330 GLN A OE1 1 
ATOM   2452  N NE2 . GLN A 1 330 ? 132.074 68.185  89.159  1.00 95.89 ? 330 GLN A NE2 1 
ATOM   2453  N N   . ARG A 1 331 ? 130.881 72.262  88.671  1.00 93.77 ? 331 ARG A N   1 
ATOM   2454  C CA  . ARG A 1 331 ? 131.072 73.530  87.974  1.00 93.77 ? 331 ARG A CA  1 
ATOM   2455  C C   . ARG A 1 331 ? 131.138 73.248  86.475  1.00 93.77 ? 331 ARG A C   1 
ATOM   2456  O O   . ARG A 1 331 ? 131.997 72.493  86.008  1.00 93.77 ? 331 ARG A O   1 
ATOM   2457  C CB  . ARG A 1 331 ? 132.316 74.259  88.487  1.00 93.77 ? 331 ARG A CB  1 
ATOM   2458  C CG  . ARG A 1 331 ? 133.651 73.599  88.182  1.00 93.77 ? 331 ARG A CG  1 
ATOM   2459  C CD  . ARG A 1 331 ? 134.825 74.392  88.739  1.00 93.77 ? 331 ARG A CD  1 
ATOM   2460  N NE  . ARG A 1 331 ? 134.867 74.359  90.195  1.00 93.77 ? 331 ARG A NE  1 
ATOM   2461  C CZ  . ARG A 1 331 ? 134.598 75.398  90.975  1.00 93.77 ? 331 ARG A CZ  1 
ATOM   2462  N NH1 . ARG A 1 331 ? 134.267 76.561  90.442  1.00 93.77 ? 331 ARG A NH1 1 
ATOM   2463  N NH2 . ARG A 1 331 ? 134.659 75.269  92.291  1.00 93.77 ? 331 ARG A NH2 1 
ATOM   2464  N N   . GLU A 1 332 ? 130.193 73.814  85.728  1.00 93.69 ? 332 GLU A N   1 
ATOM   2465  C CA  . GLU A 1 332 ? 130.158 73.610  84.285  1.00 93.69 ? 332 GLU A CA  1 
ATOM   2466  C C   . GLU A 1 332 ? 130.925 74.708  83.558  1.00 93.69 ? 332 GLU A C   1 
ATOM   2467  O O   . GLU A 1 332 ? 131.752 74.432  82.684  1.00 93.69 ? 332 GLU A O   1 
ATOM   2468  C CB  . GLU A 1 332 ? 128.705 73.541  83.805  1.00 93.69 ? 332 GLU A CB  1 
ATOM   2469  C CG  . GLU A 1 332 ? 127.819 74.693  84.264  1.00 93.69 ? 332 GLU A CG  1 
ATOM   2470  C CD  . GLU A 1 332 ? 127.280 74.503  85.667  1.00 93.69 ? 332 GLU A CD  1 
ATOM   2471  O OE1 . GLU A 1 332 ? 127.886 73.738  86.444  1.00 93.69 ? 332 GLU A OE1 1 
ATOM   2472  O OE2 . GLU A 1 332 ? 126.246 75.118  85.993  1.00 93.69 ? 332 GLU A OE2 1 
ATOM   2473  N N   . ASN A 1 333 ? 130.665 75.959  83.913  1.00 88.42 ? 333 ASN A N   1 
ATOM   2474  C CA  . ASN A 1 333 ? 131.322 77.104  83.312  1.00 88.42 ? 333 ASN A CA  1 
ATOM   2475  C C   . ASN A 1 333 ? 131.707 78.082  84.412  1.00 88.42 ? 333 ASN A C   1 
ATOM   2476  O O   . ASN A 1 333 ? 131.496 77.835  85.601  1.00 88.42 ? 333 ASN A O   1 
ATOM   2477  C CB  . ASN A 1 333 ? 130.427 77.776  82.262  1.00 88.42 ? 333 ASN A CB  1 
ATOM   2478  C CG  . ASN A 1 333 ? 129.040 78.076  82.784  1.00 88.42 ? 333 ASN A CG  1 
ATOM   2479  O OD1 . ASN A 1 333 ? 128.776 77.974  83.979  1.00 88.42 ? 333 ASN A OD1 1 
ATOM   2480  N ND2 . ASN A 1 333 ? 128.138 78.434  81.882  1.00 88.42 ? 333 ASN A ND2 1 
ATOM   2481  N N   . ASN A 1 334 ? 132.280 79.204  84.007  1.00 81.60 ? 334 ASN A N   1 
ATOM   2482  C CA  . ASN A 1 334 ? 132.822 80.177  84.935  1.00 81.60 ? 334 ASN A CA  1 
ATOM   2483  C C   . ASN A 1 334 ? 132.248 81.547  84.629  1.00 81.60 ? 334 ASN A C   1 
ATOM   2484  O O   . ASN A 1 334 ? 132.272 81.990  83.477  1.00 81.60 ? 334 ASN A O   1 
ATOM   2485  C CB  . ASN A 1 334 ? 134.339 80.184  84.843  1.00 81.60 ? 334 ASN A CB  1 
ATOM   2486  C CG  . ASN A 1 334 ? 134.935 78.895  85.325  1.00 81.60 ? 334 ASN A CG  1 
ATOM   2487  O OD1 . ASN A 1 334 ? 134.759 78.515  86.477  1.00 81.60 ? 334 ASN A OD1 1 
ATOM   2488  N ND2 . ASN A 1 334 ? 135.585 78.175  84.431  1.00 81.60 ? 334 ASN A ND2 1 
ATOM   2489  N N   . HIS A 1 335 ? 131.736 82.211  85.661  1.00 76.03 ? 335 HIS A N   1 
ATOM   2490  C CA  . HIS A 1 335 ? 131.084 83.506  85.516  1.00 76.03 ? 335 HIS A CA  1 
ATOM   2491  C C   . HIS A 1 335 ? 132.124 84.604  85.703  1.00 76.03 ? 335 HIS A C   1 
ATOM   2492  O O   . HIS A 1 335 ? 132.669 84.788  86.803  1.00 76.03 ? 335 HIS A O   1 
ATOM   2493  C CB  . HIS A 1 335 ? 129.940 83.636  86.515  1.00 76.03 ? 335 HIS A CB  1 
ATOM   2494  C CG  . HIS A 1 335 ? 128.948 84.698  86.167  1.00 76.03 ? 335 HIS A CG  1 
ATOM   2495  N ND1 . HIS A 1 335 ? 128.294 84.736  84.958  1.00 76.03 ? 335 HIS A ND1 1 
ATOM   2496  C CD2 . HIS A 1 335 ? 128.469 85.738  86.886  1.00 76.03 ? 335 HIS A CD2 1 
ATOM   2497  C CE1 . HIS A 1 335 ? 127.473 85.769  84.937  1.00 76.03 ? 335 HIS A CE1 1 
ATOM   2498  N NE2 . HIS A 1 335 ? 127.557 86.392  86.097  1.00 76.03 ? 335 HIS A NE2 1 
ATOM   2499  N N   . ILE A 1 336 ? 132.416 85.318  84.619  1.00 72.45 ? 336 ILE A N   1 
ATOM   2500  C CA  . ILE A 1 336 ? 133.384 86.398  84.624  1.00 72.45 ? 336 ILE A CA  1 
ATOM   2501  C C   . ILE A 1 336 ? 132.688 87.663  84.158  1.00 72.45 ? 336 ILE A C   1 
ATOM   2502  O O   . ILE A 1 336 ? 131.671 87.626  83.458  1.00 72.45 ? 336 ILE A O   1 
ATOM   2503  C CB  . ILE A 1 336 ? 134.594 86.083  83.730  1.00 72.45 ? 336 ILE A CB  1 
ATOM   2504  C CG1 . ILE A 1 336 ? 134.266 86.380  82.275  1.00 72.45 ? 336 ILE A CG1 1 
ATOM   2505  C CG2 . ILE A 1 336 ? 134.971 84.634  83.859  1.00 72.45 ? 336 ILE A CG2 1 
ATOM   2506  C CD1 . ILE A 1 336 ? 135.386 86.050  81.344  1.00 72.45 ? 336 ILE A CD1 1 
ATOM   2507  N N   . GLN A 1 337 ? 133.240 88.791  84.569  1.00 70.21 ? 337 GLN A N   1 
ATOM   2508  C CA  . GLN A 1 337 ? 132.760 90.089  84.128  1.00 70.21 ? 337 GLN A CA  1 
ATOM   2509  C C   . GLN A 1 337 ? 133.928 90.842  83.524  1.00 70.21 ? 337 GLN A C   1 
ATOM   2510  O O   . GLN A 1 337 ? 135.083 90.504  83.762  1.00 70.21 ? 337 GLN A O   1 
ATOM   2511  C CB  . GLN A 1 337 ? 132.149 90.889  85.270  1.00 70.21 ? 337 GLN A CB  1 
ATOM   2512  C CG  . GLN A 1 337 ? 131.009 90.189  85.957  1.00 70.21 ? 337 GLN A CG  1 
ATOM   2513  C CD  . GLN A 1 337 ? 130.632 90.863  87.251  1.00 70.21 ? 337 GLN A CD  1 
ATOM   2514  O OE1 . GLN A 1 337 ? 131.463 91.506  87.886  1.00 70.21 ? 337 GLN A OE1 1 
ATOM   2515  N NE2 . GLN A 1 337 ? 129.372 90.734  87.645  1.00 70.21 ? 337 GLN A NE2 1 
ATOM   2516  N N   . ILE A 1 338 ? 133.634 91.868  82.741  1.00 69.06 ? 338 ILE A N   1 
ATOM   2517  C CA  . ILE A 1 338 ? 134.681 92.563  82.012  1.00 69.06 ? 338 ILE A CA  1 
ATOM   2518  C C   . ILE A 1 338 ? 134.287 94.017  81.828  1.00 69.06 ? 338 ILE A C   1 
ATOM   2519  O O   . ILE A 1 338 ? 133.106 94.352  81.698  1.00 69.06 ? 338 ILE A O   1 
ATOM   2520  C CB  . ILE A 1 338 ? 134.959 91.876  80.664  1.00 69.06 ? 338 ILE A CB  1 
ATOM   2521  C CG1 . ILE A 1 338 ? 136.220 92.438  80.026  1.00 69.06 ? 338 ILE A CG1 1 
ATOM   2522  C CG2 . ILE A 1 338 ? 133.776 92.015  79.762  1.00 69.06 ? 338 ILE A CG2 1 
ATOM   2523  C CD1 . ILE A 1 338 ? 137.442 92.238  80.850  1.00 69.06 ? 338 ILE A CD1 1 
ATOM   2524  N N   . ASN A 1 339 ? 135.299 94.880  81.825  1.00 69.06 ? 339 ASN A N   1 
ATOM   2525  C CA  . ASN A 1 339 ? 135.117 96.322  81.812  1.00 69.06 ? 339 ASN A CA  1 
ATOM   2526  C C   . ASN A 1 339 ? 136.282 96.948  81.068  1.00 69.06 ? 339 ASN A C   1 
ATOM   2527  O O   . ASN A 1 339 ? 137.417 96.870  81.528  1.00 69.06 ? 339 ASN A O   1 
ATOM   2528  C CB  . ASN A 1 339 ? 135.052 96.841  83.242  1.00 69.06 ? 339 ASN A CB  1 
ATOM   2529  C CG  . ASN A 1 339 ? 134.755 98.304  83.317  1.00 69.06 ? 339 ASN A CG  1 
ATOM   2530  O OD1 . ASN A 1 339 ? 135.632 99.140  83.106  1.00 69.06 ? 339 ASN A OD1 1 
ATOM   2531  N ND2 . ASN A 1 339 ? 133.510 98.631  83.636  1.00 69.06 ? 339 ASN A ND2 1 
ATOM   2532  N N   . TRP A 1 340 ? 136.006 97.557  79.923  1.00 68.99 ? 340 TRP A N   1 
ATOM   2533  C CA  . TRP A 1 340 ? 137.011 98.275  79.155  1.00 68.99 ? 340 TRP A CA  1 
ATOM   2534  C C   . TRP A 1 340 ? 136.837 99.766  79.387  1.00 68.99 ? 340 TRP A C   1 
ATOM   2535  O O   . TRP A 1 340 ? 135.747 100.229 79.715  1.00 68.99 ? 340 TRP A O   1 
ATOM   2536  C CB  . TRP A 1 340 ? 136.898 97.981  77.662  1.00 68.99 ? 340 TRP A CB  1 
ATOM   2537  C CG  . TRP A 1 340 ? 136.748 96.541  77.345  1.00 68.99 ? 340 TRP A CG  1 
ATOM   2538  C CD1 . TRP A 1 340 ? 137.744 95.642  77.152  1.00 68.99 ? 340 TRP A CD1 1 
ATOM   2539  C CD2 . TRP A 1 340 ? 135.524 95.828  77.184  1.00 68.99 ? 340 TRP A CD2 1 
ATOM   2540  N NE1 . TRP A 1 340 ? 137.218 94.410  76.877  1.00 68.99 ? 340 TRP A NE1 1 
ATOM   2541  C CE2 . TRP A 1 340 ? 135.853 94.500  76.891  1.00 68.99 ? 340 TRP A CE2 1 
ATOM   2542  C CE3 . TRP A 1 340 ? 134.182 96.185  77.259  1.00 68.99 ? 340 TRP A CE3 1 
ATOM   2543  C CZ2 . TRP A 1 340 ? 134.893 93.530  76.673  1.00 68.99 ? 340 TRP A CZ2 1 
ATOM   2544  C CZ3 . TRP A 1 340 ? 133.232 95.225  77.045  1.00 68.99 ? 340 TRP A CZ3 1 
ATOM   2545  C CH2 . TRP A 1 340 ? 133.588 93.913  76.754  1.00 68.99 ? 340 TRP A CH2 1 
ATOM   2546  N N   . GLU A 1 341 ? 137.915 100.516 79.208  1.00 73.29 ? 341 GLU A N   1 
ATOM   2547  C CA  . GLU A 1 341 ? 137.905 101.932 79.540  1.00 73.29 ? 341 GLU A CA  1 
ATOM   2548  C C   . GLU A 1 341 ? 138.578 102.742 78.447  1.00 73.29 ? 341 GLU A C   1 
ATOM   2549  O O   . GLU A 1 341 ? 139.651 102.368 77.968  1.00 73.29 ? 341 GLU A O   1 
ATOM   2550  C CB  . GLU A 1 341 ? 138.623 102.186 80.859  1.00 73.29 ? 341 GLU A CB  1 
ATOM   2551  C CG  . GLU A 1 341 ? 138.470 103.599 81.366  1.00 73.29 ? 341 GLU A CG  1 
ATOM   2552  C CD  . GLU A 1 341 ? 139.210 103.820 82.656  1.00 73.29 ? 341 GLU A CD  1 
ATOM   2553  O OE1 . GLU A 1 341 ? 140.010 102.945 83.040  1.00 73.29 ? 341 GLU A OE1 1 
ATOM   2554  O OE2 . GLU A 1 341 ? 138.950 104.843 83.303  1.00 73.29 ? 341 GLU A OE2 1 
ATOM   2555  N N   . MET A 1 342 ? 137.965 103.876 78.104  1.00 75.25 ? 342 MET A N   1 
ATOM   2556  C CA  . MET A 1 342 ? 138.442 104.790 77.077  1.00 75.25 ? 342 MET A CA  1 
ATOM   2557  C C   . MET A 1 342 ? 138.684 106.161 77.692  1.00 75.25 ? 342 MET A C   1 
ATOM   2558  O O   . MET A 1 342 ? 137.793 106.721 78.349  1.00 75.25 ? 342 MET A O   1 
ATOM   2559  C CB  . MET A 1 342 ? 137.429 104.902 75.940  1.00 75.25 ? 342 MET A CB  1 
ATOM   2560  C CG  . MET A 1 342 ? 136.850 103.581 75.519  1.00 75.25 ? 342 MET A CG  1 
ATOM   2561  S SD  . MET A 1 342 ? 135.498 103.774 74.361  1.00 75.25 ? 342 MET A SD  1 
ATOM   2562  C CE  . MET A 1 342 ? 134.476 104.918 75.259  1.00 75.25 ? 342 MET A CE  1 
ATOM   2563  N N   . SER A 1 343 ? 139.885 106.692 77.471  1.00 80.05 ? 343 SER A N   1 
ATOM   2564  C CA  . SER A 1 343 ? 140.317 107.971 78.010  1.00 80.05 ? 343 SER A CA  1 
ATOM   2565  C C   . SER A 1 343 ? 140.080 109.081 76.996  1.00 80.05 ? 343 SER A C   1 
ATOM   2566  O O   . SER A 1 343 ? 139.857 108.828 75.812  1.00 80.05 ? 343 SER A O   1 
ATOM   2567  C CB  . SER A 1 343 ? 141.793 107.921 78.395  1.00 80.05 ? 343 SER A CB  1 
ATOM   2568  O OG  . SER A 1 343 ? 142.238 109.179 78.864  1.00 80.05 ? 343 SER A OG  1 
ATOM   2569  N N   . ALA A 1 344 ? 140.144 110.324 77.478  1.00 81.13 ? 344 ALA A N   1 
ATOM   2570  C CA  . ALA A 1 344 ? 139.824 111.483 76.651  1.00 81.13 ? 344 ALA A CA  1 
ATOM   2571  C C   . ALA A 1 344 ? 141.045 112.051 75.944  1.00 81.13 ? 344 ALA A C   1 
ATOM   2572  O O   . ALA A 1 344 ? 140.982 112.369 74.751  1.00 81.13 ? 344 ALA A O   1 
ATOM   2573  C CB  . ALA A 1 344 ? 139.174 112.570 77.508  1.00 81.13 ? 344 ALA A CB  1 
ATOM   2574  N N   . LYS A 1 345 ? 142.161 112.178 76.653  1.00 86.19 ? 345 LYS A N   1 
ATOM   2575  C CA  . LYS A 1 345 ? 143.327 112.836 76.087  1.00 86.19 ? 345 LYS A CA  1 
ATOM   2576  C C   . LYS A 1 345 ? 144.035 111.973 75.052  1.00 86.19 ? 345 LYS A C   1 
ATOM   2577  O O   . LYS A 1 345 ? 144.660 112.508 74.130  1.00 86.19 ? 345 LYS A O   1 
ATOM   2578  C CB  . LYS A 1 345 ? 144.299 113.216 77.203  1.00 86.19 ? 345 LYS A CB  1 
ATOM   2579  C CG  . LYS A 1 345 ? 144.372 112.184 78.311  1.00 86.19 ? 345 LYS A CG  1 
ATOM   2580  C CD  . LYS A 1 345 ? 145.321 112.616 79.412  1.00 86.19 ? 345 LYS A CD  1 
ATOM   2581  C CE  . LYS A 1 345 ? 146.770 112.472 78.985  1.00 86.19 ? 345 LYS A CE  1 
ATOM   2582  N NZ  . LYS A 1 345 ? 147.129 111.052 78.715  1.00 86.19 ? 345 LYS A NZ  1 
ATOM   2583  N N   . ASP A 1 346 ? 143.956 110.653 75.179  1.00 88.98 ? 346 ASP A N   1 
ATOM   2584  C CA  . ASP A 1 346 ? 144.707 109.749 74.319  1.00 88.98 ? 346 ASP A CA  1 
ATOM   2585  C C   . ASP A 1 346 ? 143.767 108.848 73.534  1.00 88.98 ? 346 ASP A C   1 
ATOM   2586  O O   . ASP A 1 346 ? 142.542 108.958 73.621  1.00 88.98 ? 346 ASP A O   1 
ATOM   2587  C CB  . ASP A 1 346 ? 145.678 108.895 75.136  1.00 88.98 ? 346 ASP A CB  1 
ATOM   2588  C CG  . ASP A 1 346 ? 146.756 109.715 75.797  1.00 88.98 ? 346 ASP A CG  1 
ATOM   2589  O OD1 . ASP A 1 346 ? 146.880 110.910 75.462  1.00 88.98 ? 346 ASP A OD1 1 
ATOM   2590  O OD2 . ASP A 1 346 ? 147.485 109.166 76.646  1.00 88.98 ? 346 ASP A OD2 1 
ATOM   2591  N N   . SER A 1 347 ? 144.363 107.944 72.761  1.00 87.64 ? 347 SER A N   1 
ATOM   2592  C CA  . SER A 1 347 ? 143.630 106.914 72.033  1.00 87.64 ? 347 SER A CA  1 
ATOM   2593  C C   . SER A 1 347 ? 144.033 105.550 72.589  1.00 87.64 ? 347 SER A C   1 
ATOM   2594  O O   . SER A 1 347 ? 144.902 104.853 72.065  1.00 87.64 ? 347 SER A O   1 
ATOM   2595  C CB  . SER A 1 347 ? 143.906 107.017 70.537  1.00 87.64 ? 347 SER A CB  1 
ATOM   2596  O OG  . SER A 1 347 ? 143.784 108.356 70.098  1.00 87.64 ? 347 SER A OG  1 
ATOM   2597  N N   . SER A 1 348 ? 143.366 105.170 73.672  1.00 84.44 ? 348 SER A N   1 
ATOM   2598  C CA  . SER A 1 348 ? 143.668 103.940 74.383  1.00 84.44 ? 348 SER A CA  1 
ATOM   2599  C C   . SER A 1 348 ? 142.386 103.406 74.995  1.00 84.44 ? 348 SER A C   1 
ATOM   2600  O O   . SER A 1 348 ? 141.456 104.167 75.266  1.00 84.44 ? 348 SER A O   1 
ATOM   2601  C CB  . SER A 1 348 ? 144.723 104.166 75.476  1.00 84.44 ? 348 SER A CB  1 
ATOM   2602  O OG  . SER A 1 348 ? 144.922 103.001 76.254  1.00 84.44 ? 348 SER A OG  1 
ATOM   2603  N N   . VAL A 1 349 ? 142.338 102.096 75.192  1.00 77.12 ? 349 VAL A N   1 
ATOM   2604  C CA  . VAL A 1 349 ? 141.243 101.449 75.901  1.00 77.12 ? 349 VAL A CA  1 
ATOM   2605  C C   . VAL A 1 349 ? 141.796 100.219 76.595  1.00 77.12 ? 349 VAL A C   1 
ATOM   2606  O O   . VAL A 1 349 ? 142.498 99.412  75.978  1.00 77.12 ? 349 VAL A O   1 
ATOM   2607  C CB  . VAL A 1 349 ? 140.080 101.089 74.961  1.00 77.12 ? 349 VAL A CB  1 
ATOM   2608  C CG1 . VAL A 1 349 ? 140.596 100.407 73.718  1.00 77.12 ? 349 VAL A CG1 1 
ATOM   2609  C CG2 . VAL A 1 349 ? 139.088 100.202 75.683  1.00 77.12 ? 349 VAL A CG2 1 
ATOM   2610  N N   . ALA A 1 350 ? 141.496 100.087 77.880  1.00 75.42 ? 350 ALA A N   1 
ATOM   2611  C CA  . ALA A 1 350 ? 142.131 99.089  78.728  1.00 75.42 ? 350 ALA A CA  1 
ATOM   2612  C C   . ALA A 1 350 ? 141.090 98.192  79.389  1.00 75.42 ? 350 ALA A C   1 
ATOM   2613  O O   . ALA A 1 350 ? 140.008 98.657  79.752  1.00 75.42 ? 350 ALA A O   1 
ATOM   2614  C CB  . ALA A 1 350 ? 143.000 99.751  79.807  1.00 75.42 ? 350 ALA A CB  1 
ATOM   2615  N N   . PRO A 1 351 ? 141.394 96.902  79.555  1.00 70.89 ? 351 PRO A N   1 
ATOM   2616  C CA  . PRO A 1 351 ? 140.415 95.985  80.143  1.00 70.89 ? 351 PRO A CA  1 
ATOM   2617  C C   . PRO A 1 351 ? 140.575 95.799  81.645  1.00 70.89 ? 351 PRO A C   1 
ATOM   2618  O O   . PRO A 1 351 ? 141.584 96.188  82.239  1.00 70.89 ? 351 PRO A O   1 
ATOM   2619  C CB  . PRO A 1 351 ? 140.695 94.685  79.394  1.00 70.89 ? 351 PRO A CB  1 
ATOM   2620  C CG  . PRO A 1 351 ? 142.162 94.726  79.190  1.00 70.89 ? 351 PRO A CG  1 
ATOM   2621  C CD  . PRO A 1 351 ? 142.580 96.176  79.085  1.00 70.89 ? 351 PRO A CD  1 
ATOM   2622  N N   . LYS A 1 352 ? 139.556 95.204  82.259  1.00 69.00 ? 352 LYS A N   1 
ATOM   2623  C CA  . LYS A 1 352 ? 139.550 94.881  83.681  1.00 69.00 ? 352 LYS A CA  1 
ATOM   2624  C C   . LYS A 1 352 ? 138.548 93.758  83.894  1.00 69.00 ? 352 LYS A C   1 
ATOM   2625  O O   . LYS A 1 352 ? 137.350 93.937  83.654  1.00 69.00 ? 352 LYS A O   1 
ATOM   2626  C CB  . LYS A 1 352 ? 139.193 96.101  84.517  1.00 69.00 ? 352 LYS A CB  1 
ATOM   2627  C CG  . LYS A 1 352 ? 138.905 95.809  85.962  1.00 69.00 ? 352 LYS A CG  1 
ATOM   2628  C CD  . LYS A 1 352 ? 138.438 97.066  86.631  1.00 69.00 ? 352 LYS A CD  1 
ATOM   2629  C CE  . LYS A 1 352 ? 137.688 96.770  87.894  1.00 69.00 ? 352 LYS A CE  1 
ATOM   2630  N NZ  . LYS A 1 352 ? 136.889 97.943  88.331  1.00 69.00 ? 352 LYS A NZ  1 
ATOM   2631  N N   . LEU A 1 353 ? 139.043 92.613  84.341  1.00 69.92 ? 353 LEU A N   1 
ATOM   2632  C CA  . LEU A 1 353 ? 138.295 91.370  84.400  1.00 69.92 ? 353 LEU A CA  1 
ATOM   2633  C C   . LEU A 1 353 ? 137.867 91.077  85.833  1.00 69.92 ? 353 LEU A C   1 
ATOM   2634  O O   . LEU A 1 353 ? 138.437 91.599  86.789  1.00 69.92 ? 353 LEU A O   1 
ATOM   2635  C CB  . LEU A 1 353 ? 139.158 90.239  83.835  1.00 69.92 ? 353 LEU A CB  1 
ATOM   2636  C CG  . LEU A 1 353 ? 138.816 88.754  83.804  1.00 69.92 ? 353 LEU A CG  1 
ATOM   2637  C CD1 . LEU A 1 353 ? 137.416 88.488  83.330  1.00 69.92 ? 353 LEU A CD1 1 
ATOM   2638  C CD2 . LEU A 1 353 ? 139.779 88.130  82.843  1.00 69.92 ? 353 LEU A CD2 1 
ATOM   2639  N N   . TYR A 1 354 ? 136.833 90.262  85.971  1.00 69.03 ? 354 TYR A N   1 
ATOM   2640  C CA  . TYR A 1 354 ? 136.268 89.893  87.257  1.00 69.03 ? 354 TYR A CA  1 
ATOM   2641  C C   . TYR A 1 354 ? 136.023 88.398  87.257  1.00 69.03 ? 354 TYR A C   1 
ATOM   2642  O O   . TYR A 1 354 ? 135.471 87.867  86.289  1.00 69.03 ? 354 TYR A O   1 
ATOM   2643  C CB  . TYR A 1 354 ? 134.915 90.562  87.515  1.00 69.03 ? 354 TYR A CB  1 
ATOM   2644  C CG  . TYR A 1 354 ? 134.869 92.064  87.547  1.00 69.03 ? 354 TYR A CG  1 
ATOM   2645  C CD1 . TYR A 1 354 ? 134.985 92.799  86.384  1.00 69.03 ? 354 TYR A CD1 1 
ATOM   2646  C CD2 . TYR A 1 354 ? 134.680 92.747  88.733  1.00 69.03 ? 354 TYR A CD2 1 
ATOM   2647  C CE1 . TYR A 1 354 ? 134.926 94.170  86.399  1.00 69.03 ? 354 TYR A CE1 1 
ATOM   2648  C CE2 . TYR A 1 354 ? 134.611 94.119  88.757  1.00 69.03 ? 354 TYR A CE2 1 
ATOM   2649  C CZ  . TYR A 1 354 ? 134.739 94.826  87.583  1.00 69.03 ? 354 TYR A CZ  1 
ATOM   2650  O OH  . TYR A 1 354 ? 134.680 96.198  87.582  1.00 69.03 ? 354 TYR A OH  1 
ATOM   2651  N N   . LEU A 1 355 ? 136.376 87.732  88.349  1.00 67.53 ? 355 LEU A N   1 
ATOM   2652  C CA  . LEU A 1 355 ? 135.905 86.380  88.602  1.00 67.53 ? 355 LEU A CA  1 
ATOM   2653  C C   . LEU A 1 355 ? 134.861 86.446  89.703  1.00 67.53 ? 355 LEU A C   1 
ATOM   2654  O O   . LEU A 1 355 ? 135.148 86.938  90.802  1.00 67.53 ? 355 LEU A O   1 
ATOM   2655  C CB  . LEU A 1 355 ? 137.046 85.452  89.001  1.00 67.53 ? 355 LEU A CB  1 
ATOM   2656  C CG  . LEU A 1 355 ? 138.115 85.204  87.947  1.00 67.53 ? 355 LEU A CG  1 
ATOM   2657  C CD1 . LEU A 1 355 ? 138.798 83.883  88.222  1.00 67.53 ? 355 LEU A CD1 1 
ATOM   2658  C CD2 . LEU A 1 355 ? 137.519 85.218  86.564  1.00 67.53 ? 355 LEU A CD2 1 
ATOM   2659  N N   . THR A 1 356 ? 133.652 85.973  89.409  1.00 66.09 ? 356 THR A N   1 
ATOM   2660  C CA  . THR A 1 356 ? 132.620 85.927  90.428  1.00 66.09 ? 356 THR A CA  1 
ATOM   2661  C C   . THR A 1 356 ? 132.837 84.720  91.330  1.00 66.09 ? 356 THR A C   1 
ATOM   2662  O O   . THR A 1 356 ? 133.002 83.596  90.850  1.00 66.09 ? 356 THR A O   1 
ATOM   2663  C CB  . THR A 1 356 ? 131.248 85.869  89.778  1.00 66.09 ? 356 THR A CB  1 
ATOM   2664  O OG1 . THR A 1 356 ? 131.139 86.929  88.826  1.00 66.09 ? 356 THR A OG1 1 
ATOM   2665  C CG2 . THR A 1 356 ? 130.167 86.020  90.817  1.00 66.09 ? 356 THR A CG2 1 
ATOM   2666  N N   . VAL A 1 357 ? 132.848 84.958  92.640  1.00 68.19 ? 357 VAL A N   1 
ATOM   2667  C CA  . VAL A 1 357 ? 133.102 83.927  93.635  1.00 68.19 ? 357 VAL A CA  1 
ATOM   2668  C C   . VAL A 1 357 ? 131.978 83.866  94.662  1.00 68.19 ? 357 VAL A C   1 
ATOM   2669  O O   . VAL A 1 357 ? 132.194 83.471  95.804  1.00 68.19 ? 357 VAL A O   1 
ATOM   2670  C CB  . VAL A 1 357 ? 134.464 84.144  94.319  1.00 68.19 ? 357 VAL A CB  1 
ATOM   2671  C CG1 . VAL A 1 357 ? 135.564 84.112  93.294  1.00 68.19 ? 357 VAL A CG1 1 
ATOM   2672  C CG2 . VAL A 1 357 ? 134.485 85.458  95.061  1.00 68.19 ? 357 VAL A CG2 1 
ATOM   2673  N N   . ILE A 1 358 ? 130.770 84.255  94.259  1.00 71.15 ? 358 ILE A N   1 
ATOM   2674  C CA  . ILE A 1 358 ? 129.649 84.315  95.187  1.00 71.15 ? 358 ILE A CA  1 
ATOM   2675  C C   . ILE A 1 358 ? 129.358 82.953  95.798  1.00 71.15 ? 358 ILE A C   1 
ATOM   2676  O O   . ILE A 1 358 ? 128.828 82.865  96.912  1.00 71.15 ? 358 ILE A O   1 
ATOM   2677  C CB  . ILE A 1 358 ? 128.415 84.890  94.469  1.00 71.15 ? 358 ILE A CB  1 
ATOM   2678  C CG1 . ILE A 1 358 ? 127.231 84.998  95.424  1.00 71.15 ? 358 ILE A CG1 1 
ATOM   2679  C CG2 . ILE A 1 358 ? 128.065 84.059  93.261  1.00 71.15 ? 358 ILE A CG2 1 
ATOM   2680  C CD1 . ILE A 1 358 ? 126.076 85.760  94.862  1.00 71.15 ? 358 ILE A CD1 1 
ATOM   2681  N N   . GLU A 1 359 ? 129.707 81.873  95.102  1.00 77.35 ? 359 GLU A N   1 
ATOM   2682  C CA  . GLU A 1 359 ? 129.296 80.535  95.503  1.00 77.35 ? 359 GLU A CA  1 
ATOM   2683  C C   . GLU A 1 359 ? 130.480 79.640  95.823  1.00 77.35 ? 359 GLU A C   1 
ATOM   2684  O O   . GLU A 1 359 ? 130.510 78.487  95.391  1.00 77.35 ? 359 GLU A O   1 
ATOM   2685  C CB  . GLU A 1 359 ? 128.448 79.894  94.408  1.00 77.35 ? 359 GLU A CB  1 
ATOM   2686  C CG  . GLU A 1 359 ? 127.172 80.640  94.076  1.00 77.35 ? 359 GLU A CG  1 
ATOM   2687  C CD  . GLU A 1 359 ? 125.939 79.962  94.633  1.00 77.35 ? 359 GLU A CD  1 
ATOM   2688  O OE1 . GLU A 1 359 ? 126.084 79.115  95.541  1.00 77.35 ? 359 GLU A OE1 1 
ATOM   2689  O OE2 . GLU A 1 359 ? 124.827 80.269  94.152  1.00 77.35 ? 359 GLU A OE2 1 
ATOM   2690  N N   . ASP A 1 360 ? 131.456 80.141  96.564  1.00 80.14 ? 360 ASP A N   1 
ATOM   2691  C CA  . ASP A 1 360 ? 132.680 79.403  96.815  1.00 80.14 ? 360 ASP A CA  1 
ATOM   2692  C C   . ASP A 1 360 ? 132.978 79.340  98.312  1.00 80.14 ? 360 ASP A C   1 
ATOM   2693  O O   . ASP A 1 360 ? 132.240 79.868  99.146  1.00 80.14 ? 360 ASP A O   1 
ATOM   2694  C CB  . ASP A 1 360 ? 133.832 80.042  96.043  1.00 80.14 ? 360 ASP A CB  1 
ATOM   2695  C CG  . ASP A 1 360 ? 133.676 79.896  94.547  1.00 80.14 ? 360 ASP A CG  1 
ATOM   2696  O OD1 . ASP A 1 360 ? 133.038 78.920  94.108  1.00 80.14 ? 360 ASP A OD1 1 
ATOM   2697  O OD2 . ASP A 1 360 ? 134.194 80.752  93.805  1.00 80.14 ? 360 ASP A OD2 1 
ATOM   2698  N N   . TYR A 1 361 ? 134.083 78.681  98.653  1.00 81.44 ? 361 TYR A N   1 
ATOM   2699  C CA  . TYR A 1 361 ? 134.514 78.564  100.041 1.00 81.44 ? 361 TYR A CA  1 
ATOM   2700  C C   . TYR A 1 361 ? 135.205 79.844  100.479 1.00 81.44 ? 361 TYR A C   1 
ATOM   2701  O O   . TYR A 1 361 ? 136.298 80.157  99.994  1.00 81.44 ? 361 TYR A O   1 
ATOM   2702  C CB  . TYR A 1 361 ? 135.463 77.386  100.214 1.00 81.44 ? 361 TYR A CB  1 
ATOM   2703  C CG  . TYR A 1 361 ? 134.777 76.060  100.326 1.00 81.44 ? 361 TYR A CG  1 
ATOM   2704  C CD1 . TYR A 1 361 ? 134.310 75.609  101.545 1.00 81.44 ? 361 TYR A CD1 1 
ATOM   2705  C CD2 . TYR A 1 361 ? 134.592 75.259  99.214  1.00 81.44 ? 361 TYR A CD2 1 
ATOM   2706  C CE1 . TYR A 1 361 ? 133.678 74.400  101.659 1.00 81.44 ? 361 TYR A CE1 1 
ATOM   2707  C CE2 . TYR A 1 361 ? 133.964 74.042  99.319  1.00 81.44 ? 361 TYR A CE2 1 
ATOM   2708  C CZ  . TYR A 1 361 ? 133.504 73.619  100.545 1.00 81.44 ? 361 TYR A CZ  1 
ATOM   2709  O OH  . TYR A 1 361 ? 132.873 72.405  100.665 1.00 81.44 ? 361 TYR A OH  1 
ATOM   2710  N N   . ASP A 1 362 ? 134.580 80.577  101.406 1.00 75.94 ? 362 ASP A N   1 
ATOM   2711  C CA  . ASP A 1 362 ? 135.235 81.753  101.959 1.00 75.94 ? 362 ASP A CA  1 
ATOM   2712  C C   . ASP A 1 362 ? 136.626 81.416  102.449 1.00 75.94 ? 362 ASP A C   1 
ATOM   2713  O O   . ASP A 1 362 ? 137.543 82.224  102.306 1.00 75.94 ? 362 ASP A O   1 
ATOM   2714  C CB  . ASP A 1 362 ? 134.417 82.350  103.097 1.00 75.94 ? 362 ASP A CB  1 
ATOM   2715  C CG  . ASP A 1 362 ? 133.180 83.048  102.615 1.00 75.94 ? 362 ASP A CG  1 
ATOM   2716  O OD1 . ASP A 1 362 ? 133.152 83.473  101.449 1.00 75.94 ? 362 ASP A OD1 1 
ATOM   2717  O OD2 . ASP A 1 362 ? 132.226 83.173  103.402 1.00 75.94 ? 362 ASP A OD2 1 
ATOM   2718  N N   . ALA A 1 363 ? 136.810 80.227  103.018 1.00 78.18 ? 363 ALA A N   1 
ATOM   2719  C CA  . ALA A 1 363 ? 138.151 79.798  103.386 1.00 78.18 ? 363 ALA A CA  1 
ATOM   2720  C C   . ALA A 1 363 ? 139.038 79.695  102.154 1.00 78.18 ? 363 ALA A C   1 
ATOM   2721  O O   . ALA A 1 363 ? 140.158 80.217  102.135 1.00 78.18 ? 363 ALA A O   1 
ATOM   2722  C CB  . ALA A 1 363 ? 138.094 78.465  104.126 1.00 78.18 ? 363 ALA A CB  1 
ATOM   2723  N N   . TYR A 1 364 ? 138.539 79.050  101.098 1.00 80.79 ? 364 TYR A N   1 
ATOM   2724  C CA  . TYR A 1 364 ? 139.336 78.908  99.884  1.00 80.79 ? 364 TYR A CA  1 
ATOM   2725  C C   . TYR A 1 364 ? 139.525 80.245  99.184  1.00 80.79 ? 364 TYR A C   1 
ATOM   2726  O O   . TYR A 1 364 ? 140.626 80.555  98.719  1.00 80.79 ? 364 TYR A O   1 
ATOM   2727  C CB  . TYR A 1 364 ? 138.685 77.906  98.936  1.00 80.79 ? 364 TYR A CB  1 
ATOM   2728  C CG  . TYR A 1 364 ? 138.961 76.466  99.280  1.00 80.79 ? 364 TYR A CG  1 
ATOM   2729  C CD1 . TYR A 1 364 ? 140.190 76.081  99.788  1.00 80.79 ? 364 TYR A CD1 1 
ATOM   2730  C CD2 . TYR A 1 364 ? 137.991 75.492  99.096  1.00 80.79 ? 364 TYR A CD2 1 
ATOM   2731  C CE1 . TYR A 1 364 ? 140.447 74.768  100.103 1.00 80.79 ? 364 TYR A CE1 1 
ATOM   2732  C CE2 . TYR A 1 364 ? 138.235 74.179  99.411  1.00 80.79 ? 364 TYR A CE2 1 
ATOM   2733  C CZ  . TYR A 1 364 ? 139.466 73.820  99.913  1.00 80.79 ? 364 TYR A CZ  1 
ATOM   2734  O OH  . TYR A 1 364 ? 139.716 72.506  100.229 1.00 80.79 ? 364 TYR A OH  1 
ATOM   2735  N N   . VAL A 1 365 ? 138.458 81.039  99.079  1.00 75.66 ? 365 VAL A N   1 
ATOM   2736  C CA  . VAL A 1 365 ? 138.577 82.352  98.453  1.00 75.66 ? 365 VAL A CA  1 
ATOM   2737  C C   . VAL A 1 365 ? 139.609 83.186  99.191  1.00 75.66 ? 365 VAL A C   1 
ATOM   2738  O O   . VAL A 1 365 ? 140.500 83.787  98.582  1.00 75.66 ? 365 VAL A O   1 
ATOM   2739  C CB  . VAL A 1 365 ? 137.213 83.060  98.413  1.00 75.66 ? 365 VAL A CB  1 
ATOM   2740  C CG1 . VAL A 1 365 ? 137.365 84.433  97.821  1.00 75.66 ? 365 VAL A CG1 1 
ATOM   2741  C CG2 . VAL A 1 365 ? 136.224 82.255  97.619  1.00 75.66 ? 365 VAL A CG2 1 
ATOM   2742  N N   . SER A 1 366 ? 139.503 83.229  100.518 1.00 74.45 ? 366 SER A N   1 
ATOM   2743  C CA  . SER A 1 366 ? 140.463 83.970  101.322 1.00 74.45 ? 366 SER A CA  1 
ATOM   2744  C C   . SER A 1 366 ? 141.870 83.443  101.123 1.00 74.45 ? 366 SER A C   1 
ATOM   2745  O O   . SER A 1 366 ? 142.816 84.225  101.018 1.00 74.45 ? 366 SER A O   1 
ATOM   2746  C CB  . SER A 1 366 ? 140.087 83.891  102.794 1.00 74.45 ? 366 SER A CB  1 
ATOM   2747  O OG  . SER A 1 366 ? 138.827 84.479  103.023 1.00 74.45 ? 366 SER A OG  1 
ATOM   2748  N N   . SER A 1 367 ? 142.036 82.120  101.086 1.00 77.33 ? 367 SER A N   1 
ATOM   2749  C CA  . SER A 1 367 ? 143.370 81.561  100.924 1.00 77.33 ? 367 SER A CA  1 
ATOM   2750  C C   . SER A 1 367 ? 143.967 81.968  99.588  1.00 77.33 ? 367 SER A C   1 
ATOM   2751  O O   . SER A 1 367 ? 145.148 82.324  99.505  1.00 77.33 ? 367 SER A O   1 
ATOM   2752  C CB  . SER A 1 367 ? 143.320 80.043  101.048 1.00 77.33 ? 367 SER A CB  1 
ATOM   2753  O OG  . SER A 1 367 ? 144.627 79.503  101.102 1.00 77.33 ? 367 SER A OG  1 
ATOM   2754  N N   . ALA A 1 368 ? 143.155 81.938  98.534  1.00 76.94 ? 368 ALA A N   1 
ATOM   2755  C CA  . ALA A 1 368 ? 143.639 82.352  97.224  1.00 76.94 ? 368 ALA A CA  1 
ATOM   2756  C C   . ALA A 1 368 ? 143.997 83.829  97.217  1.00 76.94 ? 368 ALA A C   1 
ATOM   2757  O O   . ALA A 1 368 ? 145.013 84.229  96.638  1.00 76.94 ? 368 ALA A O   1 
ATOM   2758  C CB  . ALA A 1 368 ? 142.593 82.049  96.158  1.00 76.94 ? 368 ALA A CB  1 
ATOM   2759  N N   . ILE A 1 369 ? 143.180 84.659  97.860  1.00 75.50 ? 369 ILE A N   1 
ATOM   2760  C CA  . ILE A 1 369 ? 143.488 86.083  97.907  1.00 75.50 ? 369 ILE A CA  1 
ATOM   2761  C C   . ILE A 1 369 ? 144.803 86.308  98.637  1.00 75.50 ? 369 ILE A C   1 
ATOM   2762  O O   . ILE A 1 369 ? 145.689 87.025  98.156  1.00 75.50 ? 369 ILE A O   1 
ATOM   2763  C CB  . ILE A 1 369 ? 142.341 86.868  98.561  1.00 75.50 ? 369 ILE A CB  1 
ATOM   2764  C CG1 . ILE A 1 369 ? 141.068 86.739  97.734  1.00 75.50 ? 369 ILE A CG1 1 
ATOM   2765  C CG2 . ILE A 1 369 ? 142.716 88.322  98.677  1.00 75.50 ? 369 ILE A CG2 1 
ATOM   2766  C CD1 . ILE A 1 369 ? 139.914 87.519  98.288  1.00 75.50 ? 369 ILE A CD1 1 
ATOM   2767  N N   . VAL A 1 370 ? 144.965 85.672  99.793  1.00 77.47 ? 370 VAL A N   1 
ATOM   2768  C CA  . VAL A 1 370 ? 146.135 85.956  100.608 1.00 77.47 ? 370 VAL A CA  1 
ATOM   2769  C C   . VAL A 1 370 ? 147.397 85.397  99.964  1.00 77.47 ? 370 VAL A C   1 
ATOM   2770  O O   . VAL A 1 370 ? 148.461 86.020  100.038 1.00 77.47 ? 370 VAL A O   1 
ATOM   2771  C CB  . VAL A 1 370 ? 145.943 85.445  102.045 1.00 77.47 ? 370 VAL A CB  1 
ATOM   2772  C CG1 . VAL A 1 370 ? 144.651 85.977  102.619 1.00 77.47 ? 370 VAL A CG1 1 
ATOM   2773  C CG2 . VAL A 1 370 ? 145.969 83.939  102.095 1.00 77.47 ? 370 VAL A CG2 1 
ATOM   2774  N N   . ASP A 1 371 ? 147.315 84.252  99.281  1.00 80.25 ? 371 ASP A N   1 
ATOM   2775  C CA  . ASP A 1 371 ? 148.560 83.757  98.703  1.00 80.25 ? 371 ASP A CA  1 
ATOM   2776  C C   . ASP A 1 371 ? 148.862 84.405  97.355  1.00 80.25 ? 371 ASP A C   1 
ATOM   2777  O O   . ASP A 1 371 ? 150.034 84.521  96.983  1.00 80.25 ? 371 ASP A O   1 
ATOM   2778  C CB  . ASP A 1 371 ? 148.554 82.229  98.605  1.00 80.25 ? 371 ASP A CB  1 
ATOM   2779  C CG  . ASP A 1 371 ? 147.509 81.697  97.664  1.00 80.25 ? 371 ASP A CG  1 
ATOM   2780  O OD1 . ASP A 1 371 ? 146.697 82.489  97.176  1.00 80.25 ? 371 ASP A OD1 1 
ATOM   2781  O OD2 . ASP A 1 371 ? 147.501 80.472  97.412  1.00 80.25 ? 371 ASP A OD2 1 
ATOM   2782  N N   . LEU A 1 372 ? 147.841 84.861  96.626  1.00 79.88 ? 372 LEU A N   1 
ATOM   2783  C CA  . LEU A 1 372 ? 148.079 85.764  95.507  1.00 79.88 ? 372 LEU A CA  1 
ATOM   2784  C C   . LEU A 1 372 ? 148.834 86.997  95.970  1.00 79.88 ? 372 LEU A C   1 
ATOM   2785  O O   . LEU A 1 372 ? 149.864 87.370  95.396  1.00 79.88 ? 372 LEU A O   1 
ATOM   2786  C CB  . LEU A 1 372 ? 146.749 86.167  94.876  1.00 79.88 ? 372 LEU A CB  1 
ATOM   2787  C CG  . LEU A 1 372 ? 146.836 87.171  93.730  1.00 79.88 ? 372 LEU A CG  1 
ATOM   2788  C CD1 . LEU A 1 372 ? 147.599 86.590  92.556  1.00 79.88 ? 372 LEU A CD1 1 
ATOM   2789  C CD2 . LEU A 1 372 ? 145.442 87.595  93.314  1.00 79.88 ? 372 LEU A CD2 1 
ATOM   2790  N N   . PHE A 1 373 ? 148.319 87.644  97.012  1.00 78.85 ? 373 PHE A N   1 
ATOM   2791  C CA  . PHE A 1 373 ? 149.022 88.766  97.607  1.00 78.85 ? 373 PHE A CA  1 
ATOM   2792  C C   . PHE A 1 373 ? 150.444 88.389  97.988  1.00 78.85 ? 373 PHE A C   1 
ATOM   2793  O O   . PHE A 1 373 ? 151.389 89.139  97.718  1.00 78.85 ? 373 PHE A O   1 
ATOM   2794  C CB  . PHE A 1 373 ? 148.260 89.245  98.830  1.00 78.85 ? 373 PHE A CB  1 
ATOM   2795  C CG  . PHE A 1 373 ? 147.134 90.168  98.516  1.00 78.85 ? 373 PHE A CG  1 
ATOM   2796  C CD1 . PHE A 1 373 ? 146.958 90.658  97.246  1.00 78.85 ? 373 PHE A CD1 1 
ATOM   2797  C CD2 . PHE A 1 373 ? 146.260 90.559  99.505  1.00 78.85 ? 373 PHE A CD2 1 
ATOM   2798  C CE1 . PHE A 1 373 ? 145.927 91.511  96.972  1.00 78.85 ? 373 PHE A CE1 1 
ATOM   2799  C CE2 . PHE A 1 373 ? 145.234 91.408  99.236  1.00 78.85 ? 373 PHE A CE2 1 
ATOM   2800  C CZ  . PHE A 1 373 ? 145.064 91.887  97.972  1.00 78.85 ? 373 PHE A CZ  1 
ATOM   2801  N N   . THR A 1 374 ? 150.618 87.227  98.616  1.00 81.50 ? 374 THR A N   1 
ATOM   2802  C CA  . THR A 1 374 ? 151.932 86.853  99.116  1.00 81.50 ? 374 THR A CA  1 
ATOM   2803  C C   . THR A 1 374 ? 152.923 86.670  97.980  1.00 81.50 ? 374 THR A C   1 
ATOM   2804  O O   . THR A 1 374 ? 154.062 87.144  98.060  1.00 81.50 ? 374 THR A O   1 
ATOM   2805  C CB  . THR A 1 374 ? 151.828 85.583  99.949  1.00 81.50 ? 374 THR A CB  1 
ATOM   2806  O OG1 . THR A 1 374 ? 150.991 85.843  101.081 1.00 81.50 ? 374 THR A OG1 1 
ATOM   2807  C CG2 . THR A 1 374 ? 153.200 85.145  100.424 1.00 81.50 ? 374 THR A CG2 1 
ATOM   2808  N N   . GLY A 1 375 ? 152.510 85.992  96.913  1.00 84.29 ? 375 GLY A N   1 
ATOM   2809  C CA  . GLY A 1 375 ? 153.340 85.951  95.723  1.00 84.29 ? 375 GLY A CA  1 
ATOM   2810  C C   . GLY A 1 375 ? 153.649 87.341  95.205  1.00 84.29 ? 375 GLY A C   1 
ATOM   2811  O O   . GLY A 1 375 ? 154.772 87.626  94.783  1.00 84.29 ? 375 GLY A O   1 
ATOM   2812  N N   . LEU A 1 376 ? 152.658 88.229  95.246  1.00 82.23 ? 376 LEU A N   1 
ATOM   2813  C CA  . LEU A 1 376 ? 152.868 89.610  94.838  1.00 82.23 ? 376 LEU A CA  1 
ATOM   2814  C C   . LEU A 1 376 ? 153.709 90.396  95.833  1.00 82.23 ? 376 LEU A C   1 
ATOM   2815  O O   . LEU A 1 376 ? 154.146 91.505  95.516  1.00 82.23 ? 376 LEU A O   1 
ATOM   2816  C CB  . LEU A 1 376 ? 151.523 90.296  94.643  1.00 82.23 ? 376 LEU A CB  1 
ATOM   2817  C CG  . LEU A 1 376 ? 151.465 91.142  93.383  1.00 82.23 ? 376 LEU A CG  1 
ATOM   2818  C CD1 . LEU A 1 376 ? 150.864 90.316  92.285  1.00 82.23 ? 376 LEU A CD1 1 
ATOM   2819  C CD2 . LEU A 1 376 ? 150.636 92.396  93.629  1.00 82.23 ? 376 LEU A CD2 1 
ATOM   2820  N N   . GLY A 1 377 ? 153.929 89.862  97.030  1.00 80.16 ? 377 GLY A N   1 
ATOM   2821  C CA  . GLY A 1 377 ? 154.688 90.575  98.032  1.00 80.16 ? 377 GLY A CA  1 
ATOM   2822  C C   . GLY A 1 377 ? 153.928 91.652  98.768  1.00 80.16 ? 377 GLY A C   1 
ATOM   2823  O O   . GLY A 1 377 ? 154.550 92.464  99.455  1.00 80.16 ? 377 GLY A O   1 
ATOM   2824  N N   . TRP A 1 378 ? 152.602 91.692  98.650  1.00 76.52 ? 378 TRP A N   1 
ATOM   2825  C CA  . TRP A 1 378 ? 151.791 92.683  99.357  1.00 76.52 ? 378 TRP A CA  1 
ATOM   2826  C C   . TRP A 1 378 ? 151.523 92.250  100.801 1.00 76.52 ? 378 TRP A C   1 
ATOM   2827  O O   . TRP A 1 378 ? 150.383 92.064  101.224 1.00 76.52 ? 378 TRP A O   1 
ATOM   2828  C CB  . TRP A 1 378 ? 150.485 92.919  98.611  1.00 76.52 ? 378 TRP A CB  1 
ATOM   2829  C CG  . TRP A 1 378 ? 150.598 93.852  97.456  1.00 76.52 ? 378 TRP A CG  1 
ATOM   2830  C CD1 . TRP A 1 378 ? 151.704 94.540  97.060  1.00 76.52 ? 378 TRP A CD1 1 
ATOM   2831  C CD2 . TRP A 1 378 ? 149.562 94.192  96.530  1.00 76.52 ? 378 TRP A CD2 1 
ATOM   2832  N NE1 . TRP A 1 378 ? 151.419 95.296  95.950  1.00 76.52 ? 378 TRP A NE1 1 
ATOM   2833  C CE2 . TRP A 1 378 ? 150.108 95.097  95.605  1.00 76.52 ? 378 TRP A CE2 1 
ATOM   2834  C CE3 . TRP A 1 378 ? 148.223 93.820  96.396  1.00 76.52 ? 378 TRP A CE3 1 
ATOM   2835  C CZ2 . TRP A 1 378 ? 149.362 95.632  94.559  1.00 76.52 ? 378 TRP A CZ2 1 
ATOM   2836  C CZ3 . TRP A 1 378 ? 147.485 94.354  95.360  1.00 76.52 ? 378 TRP A CZ3 1 
ATOM   2837  C CH2 . TRP A 1 378 ? 148.054 95.246  94.454  1.00 76.52 ? 378 TRP A CH2 1 
ATOM   2838  N N   . ALA A 1 379 ? 152.605 92.111  101.571 1.00 76.08 ? 379 ALA A N   1 
ATOM   2839  C CA  . ALA A 1 379 ? 152.476 91.604  102.935 1.00 76.08 ? 379 ALA A CA  1 
ATOM   2840  C C   . ALA A 1 379 ? 151.698 92.567  103.823 1.00 76.08 ? 379 ALA A C   1 
ATOM   2841  O O   . ALA A 1 379 ? 150.830 92.145  104.597 1.00 76.08 ? 379 ALA A O   1 
ATOM   2842  C CB  . ALA A 1 379 ? 153.854 91.334  103.527 1.00 76.08 ? 379 ALA A CB  1 
ATOM   2843  N N   . ALA A 1 380 ? 152.018 93.858  103.753 1.00 75.11 ? 380 ALA A N   1 
ATOM   2844  C CA  . ALA A 1 380 ? 151.218 94.844  104.465 1.00 75.11 ? 380 ALA A CA  1 
ATOM   2845  C C   . ALA A 1 380 ? 149.757 94.709  104.078 1.00 75.11 ? 380 ALA A C   1 
ATOM   2846  O O   . ALA A 1 380 ? 148.867 94.692  104.934 1.00 75.11 ? 380 ALA A O   1 
ATOM   2847  C CB  . ALA A 1 380 ? 151.732 96.249  104.162 1.00 75.11 ? 380 ALA A CB  1 
ATOM   2848  N N   . HIS A 1 381 ? 149.497 94.585  102.780 1.00 74.12 ? 381 HIS A N   1 
ATOM   2849  C CA  . HIS A 1 381 ? 148.140 94.336  102.326 1.00 74.12 ? 381 HIS A CA  1 
ATOM   2850  C C   . HIS A 1 381 ? 147.611 93.008  102.842 1.00 74.12 ? 381 HIS A C   1 
ATOM   2851  O O   . HIS A 1 381 ? 146.405 92.871  103.054 1.00 74.12 ? 381 HIS A O   1 
ATOM   2852  C CB  . HIS A 1 381 ? 148.092 94.371  100.805 1.00 74.12 ? 381 HIS A CB  1 
ATOM   2853  C CG  . HIS A 1 381 ? 148.350 95.725  100.223 1.00 74.12 ? 381 HIS A CG  1 
ATOM   2854  N ND1 . HIS A 1 381 ? 147.402 96.726  100.216 1.00 74.12 ? 381 HIS A ND1 1 
ATOM   2855  C CD2 . HIS A 1 381 ? 149.444 96.241  99.618  1.00 74.12 ? 381 HIS A CD2 1 
ATOM   2856  C CE1 . HIS A 1 381 ? 147.900 97.798  99.629  1.00 74.12 ? 381 HIS A CE1 1 
ATOM   2857  N NE2 . HIS A 1 381 ? 149.138 97.530  99.257  1.00 74.12 ? 381 HIS A NE2 1 
ATOM   2858  N N   . VAL A 1 382 ? 148.487 92.027  103.063 1.00 74.55 ? 382 VAL A N   1 
ATOM   2859  C CA  . VAL A 1 382 ? 148.035 90.737  103.581 1.00 74.55 ? 382 VAL A CA  1 
ATOM   2860  C C   . VAL A 1 382 ? 147.477 90.897  104.988 1.00 74.55 ? 382 VAL A C   1 
ATOM   2861  O O   . VAL A 1 382 ? 146.366 90.441  105.294 1.00 74.55 ? 382 VAL A O   1 
ATOM   2862  C CB  . VAL A 1 382 ? 149.177 89.706  103.555 1.00 74.55 ? 382 VAL A CB  1 
ATOM   2863  C CG1 . VAL A 1 382 ? 148.829 88.520  104.432 1.00 74.55 ? 382 VAL A CG1 1 
ATOM   2864  C CG2 . VAL A 1 382 ? 149.462 89.245  102.147 1.00 74.55 ? 382 VAL A CG2 1 
ATOM   2865  N N   . GLN A 1 383 ? 148.259 91.514  105.874 1.00 73.07 ? 383 GLN A N   1 
ATOM   2866  C CA  . GLN A 1 383 ? 147.771 91.757  107.224 1.00 73.07 ? 383 GLN A CA  1 
ATOM   2867  C C   . GLN A 1 383 ? 146.540 92.639  107.195 1.00 73.07 ? 383 GLN A C   1 
ATOM   2868  O O   . GLN A 1 383 ? 145.598 92.425  107.960 1.00 73.07 ? 383 GLN A O   1 
ATOM   2869  C CB  . GLN A 1 383 ? 148.860 92.395  108.083 1.00 73.07 ? 383 GLN A CB  1 
ATOM   2870  C CG  . GLN A 1 383 ? 150.166 91.634  108.080 1.00 73.07 ? 383 GLN A CG  1 
ATOM   2871  C CD  . GLN A 1 383 ? 149.968 90.153  108.303 1.00 73.07 ? 383 GLN A CD  1 
ATOM   2872  O OE1 . GLN A 1 383 ? 149.329 89.740  109.267 1.00 73.07 ? 383 GLN A OE1 1 
ATOM   2873  N NE2 . GLN A 1 383 ? 150.510 89.344  107.403 1.00 73.07 ? 383 GLN A NE2 1 
ATOM   2874  N N   . THR A 1 384 ? 146.533 93.637  106.313 1.00 68.84 ? 384 THR A N   1 
ATOM   2875  C CA  . THR A 1 384 ? 145.353 94.469  106.143 1.00 68.84 ? 384 THR A CA  1 
ATOM   2876  C C   . THR A 1 384 ? 144.132 93.613  105.851 1.00 68.84 ? 384 THR A C   1 
ATOM   2877  O O   . THR A 1 384 ? 143.083 93.757  106.489 1.00 68.84 ? 384 THR A O   1 
ATOM   2878  C CB  . THR A 1 384 ? 145.589 95.460  105.010 1.00 68.84 ? 384 THR A CB  1 
ATOM   2879  O OG1 . THR A 1 384 ? 146.961 95.866  105.012 1.00 68.84 ? 384 THR A OG1 1 
ATOM   2880  C CG2 . THR A 1 384 ? 144.726 96.678  105.203 1.00 68.84 ? 384 THR A CG2 1 
ATOM   2881  N N   . HIS A 1 385 ? 144.263 92.698  104.894 1.00 67.14 ? 385 HIS A N   1 
ATOM   2882  C CA  . HIS A 1 385 ? 143.134 91.885  104.478 1.00 67.14 ? 385 HIS A CA  1 
ATOM   2883  C C   . HIS A 1 385 ? 142.650 90.996  105.611 1.00 67.14 ? 385 HIS A C   1 
ATOM   2884  O O   . HIS A 1 385 ? 141.450 90.923  105.887 1.00 67.14 ? 385 HIS A O   1 
ATOM   2885  C CB  . HIS A 1 385 ? 143.519 91.043  103.271 1.00 67.14 ? 385 HIS A CB  1 
ATOM   2886  C CG  . HIS A 1 385 ? 142.415 90.162  102.798 1.00 67.14 ? 385 HIS A CG  1 
ATOM   2887  N ND1 . HIS A 1 385 ? 142.441 88.795  102.944 1.00 67.14 ? 385 HIS A ND1 1 
ATOM   2888  C CD2 . HIS A 1 385 ? 141.233 90.458  102.209 1.00 67.14 ? 385 HIS A CD2 1 
ATOM   2889  C CE1 . HIS A 1 385 ? 141.328 88.284  102.453 1.00 67.14 ? 385 HIS A CE1 1 
ATOM   2890  N NE2 . HIS A 1 385 ? 140.577 89.271  102.002 1.00 67.14 ? 385 HIS A NE2 1 
ATOM   2891  N N   . LYS A 1 386 ? 143.575 90.307  106.279 1.00 68.27 ? 386 LYS A N   1 
ATOM   2892  C CA  . LYS A 1 386 ? 143.177 89.402  107.354 1.00 68.27 ? 386 LYS A CA  1 
ATOM   2893  C C   . LYS A 1 386 ? 142.568 90.166  108.522 1.00 68.27 ? 386 LYS A C   1 
ATOM   2894  O O   . LYS A 1 386 ? 141.628 89.689  109.167 1.00 68.27 ? 386 LYS A O   1 
ATOM   2895  C CB  . LYS A 1 386 ? 144.373 88.580  107.821 1.00 68.27 ? 386 LYS A CB  1 
ATOM   2896  C CG  . LYS A 1 386 ? 144.618 87.333  107.009 1.00 68.27 ? 386 LYS A CG  1 
ATOM   2897  C CD  . LYS A 1 386 ? 146.068 86.917  107.092 1.00 68.27 ? 386 LYS A CD  1 
ATOM   2898  C CE  . LYS A 1 386 ? 146.194 85.416  107.155 1.00 68.27 ? 386 LYS A CE  1 
ATOM   2899  N NZ  . LYS A 1 386 ? 145.439 84.880  108.315 1.00 68.27 ? 386 LYS A NZ  1 
ATOM   2900  N N   . LYS A 1 387 ? 143.097 91.350  108.814 1.00 63.63 ? 387 LYS A N   1 
ATOM   2901  C CA  . LYS A 1 387 ? 142.541 92.169  109.878 1.00 63.63 ? 387 LYS A CA  1 
ATOM   2902  C C   . LYS A 1 387 ? 141.115 92.577  109.554 1.00 63.63 ? 387 LYS A C   1 
ATOM   2903  O O   . LYS A 1 387 ? 140.207 92.415  110.378 1.00 63.63 ? 387 LYS A O   1 
ATOM   2904  C CB  . LYS A 1 387 ? 143.423 93.395  110.082 1.00 63.63 ? 387 LYS A CB  1 
ATOM   2905  C CG  . LYS A 1 387 ? 142.839 94.443  110.979 1.00 63.63 ? 387 LYS A CG  1 
ATOM   2906  C CD  . LYS A 1 387 ? 143.548 95.758  110.776 1.00 63.63 ? 387 LYS A CD  1 
ATOM   2907  C CE  . LYS A 1 387 ? 145.046 95.568  110.744 1.00 63.63 ? 387 LYS A CE  1 
ATOM   2908  N NZ  . LYS A 1 387 ? 145.757 96.868  110.661 1.00 63.63 ? 387 LYS A NZ  1 
ATOM   2909  N N   . ILE A 1 388 ? 140.905 93.128  108.358 1.00 60.92 ? 388 ILE A N   1 
ATOM   2910  C CA  . ILE A 1 388 ? 139.557 93.497  107.944 1.00 60.92 ? 388 ILE A CA  1 
ATOM   2911  C C   . ILE A 1 388 ? 138.649 92.282  107.979 1.00 60.92 ? 388 ILE A C   1 
ATOM   2912  O O   . ILE A 1 388 ? 137.473 92.375  108.343 1.00 60.92 ? 388 ILE A O   1 
ATOM   2913  C CB  . ILE A 1 388 ? 139.585 94.144  106.550 1.00 60.92 ? 388 ILE A CB  1 
ATOM   2914  C CG1 . ILE A 1 388 ? 140.493 95.364  106.564 1.00 60.92 ? 388 ILE A CG1 1 
ATOM   2915  C CG2 . ILE A 1 388 ? 138.195 94.543  106.126 1.00 60.92 ? 388 ILE A CG2 1 
ATOM   2916  C CD1 . ILE A 1 388 ? 140.652 96.017  105.234 1.00 60.92 ? 388 ILE A CD1 1 
ATOM   2917  N N   . GLU A 1 389 ? 139.191 91.119  107.631 1.00 65.90 ? 389 GLU A N   1 
ATOM   2918  C CA  . GLU A 1 389 ? 138.408 89.895  107.660 1.00 65.90 ? 389 GLU A CA  1 
ATOM   2919  C C   . GLU A 1 389 ? 137.915 89.603  109.066 1.00 65.90 ? 389 GLU A C   1 
ATOM   2920  O O   . GLU A 1 389 ? 136.711 89.611  109.334 1.00 65.90 ? 389 GLU A O   1 
ATOM   2921  C CB  . GLU A 1 389 ? 139.255 88.742  107.138 1.00 65.90 ? 389 GLU A CB  1 
ATOM   2922  C CG  . GLU A 1 389 ? 138.456 87.643  106.496 1.00 65.90 ? 389 GLU A CG  1 
ATOM   2923  C CD  . GLU A 1 389 ? 139.328 86.503  106.058 1.00 65.90 ? 389 GLU A CD  1 
ATOM   2924  O OE1 . GLU A 1 389 ? 140.311 86.208  106.769 1.00 65.90 ? 389 GLU A OE1 1 
ATOM   2925  O OE2 . GLU A 1 389 ? 139.042 85.910  105.001 1.00 65.90 ? 389 GLU A OE2 1 
ATOM   2926  N N   . LYS A 1 390 ? 138.851 89.372  109.985 1.00 64.87 ? 390 LYS A N   1 
ATOM   2927  C CA  . LYS A 1 390 ? 138.494 88.987  111.345 1.00 64.87 ? 390 LYS A CA  1 
ATOM   2928  C C   . LYS A 1 390 ? 137.579 90.013  111.995 1.00 64.87 ? 390 LYS A C   1 
ATOM   2929  O O   . LYS A 1 390 ? 136.579 89.653  112.623 1.00 64.87 ? 390 LYS A O   1 
ATOM   2930  C CB  . LYS A 1 390 ? 139.759 88.798  112.175 1.00 64.87 ? 390 LYS A CB  1 
ATOM   2931  C CG  . LYS A 1 390 ? 139.501 88.361  113.592 1.00 64.87 ? 390 LYS A CG  1 
ATOM   2932  C CD  . LYS A 1 390 ? 140.797 88.244  114.365 1.00 64.87 ? 390 LYS A CD  1 
ATOM   2933  C CE  . LYS A 1 390 ? 141.522 89.575  114.402 1.00 64.87 ? 390 LYS A CE  1 
ATOM   2934  N NZ  . LYS A 1 390 ? 142.815 89.490  115.131 1.00 64.87 ? 390 LYS A NZ  1 
ATOM   2935  N N   . GLU A 1 391 ? 137.889 91.297  111.841 1.00 61.68 ? 391 GLU A N   1 
ATOM   2936  C CA  . GLU A 1 391 ? 137.118 92.318  112.536 1.00 61.68 ? 391 GLU A CA  1 
ATOM   2937  C C   . GLU A 1 391 ? 135.755 92.528  111.893 1.00 61.68 ? 391 GLU A C   1 
ATOM   2938  O O   . GLU A 1 391 ? 134.729 92.499  112.577 1.00 61.68 ? 391 GLU A O   1 
ATOM   2939  C CB  . GLU A 1 391 ? 137.907 93.625  112.570 1.00 61.68 ? 391 GLU A CB  1 
ATOM   2940  C CG  . GLU A 1 391 ? 139.162 93.547  113.418 1.00 61.68 ? 391 GLU A CG  1 
ATOM   2941  C CD  . GLU A 1 391 ? 139.969 94.822  113.389 1.00 61.68 ? 391 GLU A CD  1 
ATOM   2942  O OE1 . GLU A 1 391 ? 139.863 95.570  112.400 1.00 61.68 ? 391 GLU A OE1 1 
ATOM   2943  O OE2 . GLU A 1 391 ? 140.712 95.078  114.355 1.00 61.68 ? 391 GLU A OE2 1 
ATOM   2944  N N   . ALA A 1 392 ? 135.724 92.745  110.580 1.00 58.34 ? 392 ALA A N   1 
ATOM   2945  C CA  . ALA A 1 392 ? 134.481 93.064  109.899 1.00 58.34 ? 392 ALA A CA  1 
ATOM   2946  C C   . ALA A 1 392 ? 133.666 91.834  109.545 1.00 58.34 ? 392 ALA A C   1 
ATOM   2947  O O   . ALA A 1 392 ? 132.448 91.948  109.371 1.00 58.34 ? 392 ALA A O   1 
ATOM   2948  C CB  . ALA A 1 392 ? 134.771 93.860  108.632 1.00 58.34 ? 392 ALA A CB  1 
ATOM   2949  N N   . TYR A 1 393 ? 134.298 90.666  109.437 1.00 59.09 ? 393 TYR A N   1 
ATOM   2950  C CA  . TYR A 1 393 ? 133.617 89.437  109.038 1.00 59.09 ? 393 TYR A CA  1 
ATOM   2951  C C   . TYR A 1 393 ? 134.057 88.302  109.949 1.00 59.09 ? 393 TYR A C   1 
ATOM   2952  O O   . TYR A 1 393 ? 135.013 87.576  109.646 1.00 59.09 ? 393 TYR A O   1 
ATOM   2953  C CB  . TYR A 1 393 ? 133.897 89.114  107.577 1.00 59.09 ? 393 TYR A CB  1 
ATOM   2954  C CG  . TYR A 1 393 ? 133.447 90.210  106.655 1.00 59.09 ? 393 TYR A CG  1 
ATOM   2955  C CD1 . TYR A 1 393 ? 132.101 90.442  106.435 1.00 59.09 ? 393 TYR A CD1 1 
ATOM   2956  C CD2 . TYR A 1 393 ? 134.364 91.029  106.018 1.00 59.09 ? 393 TYR A CD2 1 
ATOM   2957  C CE1 . TYR A 1 393 ? 131.683 91.444  105.603 1.00 59.09 ? 393 TYR A CE1 1 
ATOM   2958  C CE2 . TYR A 1 393 ? 133.951 92.037  105.186 1.00 59.09 ? 393 TYR A CE2 1 
ATOM   2959  C CZ  . TYR A 1 393 ? 132.611 92.235  104.985 1.00 59.09 ? 393 TYR A CZ  1 
ATOM   2960  O OH  . TYR A 1 393 ? 132.192 93.235  104.155 1.00 59.09 ? 393 TYR A OH  1 
ATOM   2961  N N   . PRO A 1 394 ? 133.377 88.108  111.062 1.00 67.39 ? 394 PRO A N   1 
ATOM   2962  C CA  . PRO A 1 394 ? 133.751 87.016  111.965 1.00 67.39 ? 394 PRO A CA  1 
ATOM   2963  C C   . PRO A 1 394 ? 133.381 85.651  111.413 1.00 67.39 ? 394 PRO A C   1 
ATOM   2964  O O   . PRO A 1 394 ? 134.025 84.652  111.745 1.00 67.39 ? 394 PRO A O   1 
ATOM   2965  C CB  . PRO A 1 394 ? 132.961 87.338  113.236 1.00 67.39 ? 394 PRO A CB  1 
ATOM   2966  C CG  . PRO A 1 394 ? 131.776 88.096  112.753 1.00 67.39 ? 394 PRO A CG  1 
ATOM   2967  C CD  . PRO A 1 394 ? 132.228 88.880  111.564 1.00 67.39 ? 394 PRO A CD  1 
ATOM   2968  N N   . MET A 1 395 ? 132.351 85.608  110.562 1.00 66.67 ? 395 MET A N   1 
ATOM   2969  C CA  . MET A 1 395 ? 131.763 84.342  110.134 1.00 66.67 ? 395 MET A CA  1 
ATOM   2970  C C   . MET A 1 395 ? 132.792 83.409  109.512 1.00 66.67 ? 395 MET A C   1 
ATOM   2971  O O   . MET A 1 395 ? 132.737 82.193  109.718 1.00 66.67 ? 395 MET A O   1 
ATOM   2972  C CB  . MET A 1 395 ? 130.627 84.609  109.150 1.00 66.67 ? 395 MET A CB  1 
ATOM   2973  C CG  . MET A 1 395 ? 130.977 85.611  108.069 1.00 66.67 ? 395 MET A CG  1 
ATOM   2974  S SD  . MET A 1 395 ? 129.553 86.571  107.537 1.00 66.67 ? 395 MET A SD  1 
ATOM   2975  C CE  . MET A 1 395 ? 129.272 87.572  108.985 1.00 66.67 ? 395 MET A CE  1 
ATOM   2976  N N   . CYS A 1 396 ? 133.747 83.957  108.760 1.00 72.55 ? 396 CYS A N   1 
ATOM   2977  C CA  . CYS A 1 396 ? 134.723 83.119  108.070 1.00 72.55 ? 396 CYS A CA  1 
ATOM   2978  C C   . CYS A 1 396 ? 135.527 82.255  109.030 1.00 72.55 ? 396 CYS A C   1 
ATOM   2979  O O   . CYS A 1 396 ? 136.135 81.268  108.601 1.00 72.55 ? 396 CYS A O   1 
ATOM   2980  C CB  . CYS A 1 396 ? 135.666 83.988  107.236 1.00 72.55 ? 396 CYS A CB  1 
ATOM   2981  S SG  . CYS A 1 396 ? 136.590 85.213  108.187 1.00 72.55 ? 396 CYS A SG  1 
ATOM   2982  N N   . ASP A 1 397 ? 135.548 82.604  110.313 1.00 75.86 ? 397 ASP A N   1 
ATOM   2983  C CA  . ASP A 1 397 ? 136.179 81.793  111.341 1.00 75.86 ? 397 ASP A CA  1 
ATOM   2984  C C   . ASP A 1 397 ? 135.168 81.061  112.202 1.00 75.86 ? 397 ASP A C   1 
ATOM   2985  O O   . ASP A 1 397 ? 135.391 79.902  112.557 1.00 75.86 ? 397 ASP A O   1 
ATOM   2986  C CB  . ASP A 1 397 ? 137.065 82.663  112.231 1.00 75.86 ? 397 ASP A CB  1 
ATOM   2987  C CG  . ASP A 1 397 ? 138.191 83.308  111.463 1.00 75.86 ? 397 ASP A CG  1 
ATOM   2988  O OD1 . ASP A 1 397 ? 138.284 83.066  110.246 1.00 75.86 ? 397 ASP A OD1 1 
ATOM   2989  O OD2 . ASP A 1 397 ? 138.982 84.058  112.070 1.00 75.86 ? 397 ASP A OD2 1 
ATOM   2990  N N   . ALA A 1 398 ? 134.053 81.711  112.539 1.00 75.71 ? 398 ALA A N   1 
ATOM   2991  C CA  . ALA A 1 398 ? 133.031 81.056  113.346 1.00 75.71 ? 398 ALA A CA  1 
ATOM   2992  C C   . ALA A 1 398 ? 132.418 79.869  112.620 1.00 75.71 ? 398 ALA A C   1 
ATOM   2993  O O   . ALA A 1 398 ? 131.875 78.963  113.260 1.00 75.71 ? 398 ALA A O   1 
ATOM   2994  C CB  . ALA A 1 398 ? 131.944 82.055  113.732 1.00 75.71 ? 398 ALA A CB  1 
ATOM   2995  N N   . ASN A 1 399 ? 132.488 79.855  111.293 1.00 77.66 ? 399 ASN A N   1 
ATOM   2996  C CA  . ASN A 1 399 ? 131.921 78.786  110.486 1.00 77.66 ? 399 ASN A CA  1 
ATOM   2997  C C   . ASN A 1 399 ? 132.995 78.256  109.548 1.00 77.66 ? 399 ASN A C   1 
ATOM   2998  O O   . ASN A 1 399 ? 133.505 79.018  108.710 1.00 77.66 ? 399 ASN A O   1 
ATOM   2999  C CB  . ASN A 1 399 ? 130.719 79.297  109.693 1.00 77.66 ? 399 ASN A CB  1 
ATOM   3000  C CG  . ASN A 1 399 ? 129.881 78.184  109.117 1.00 77.66 ? 399 ASN A CG  1 
ATOM   3001  O OD1 . ASN A 1 399 ? 130.377 77.094  108.840 1.00 77.66 ? 399 ASN A OD1 1 
ATOM   3002  N ND2 . ASN A 1 399 ? 128.597 78.455  108.926 1.00 77.66 ? 399 ASN A ND2 1 
ATOM   3003  N N   . PRO A 1 400 ? 133.387 76.985  109.650 1.00 78.38 ? 400 PRO A N   1 
ATOM   3004  C CA  . PRO A 1 400 ? 134.346 76.449  108.670 1.00 78.38 ? 400 PRO A CA  1 
ATOM   3005  C C   . PRO A 1 400 ? 133.800 76.450  107.258 1.00 78.38 ? 400 PRO A C   1 
ATOM   3006  O O   . PRO A 1 400 ? 134.529 76.769  106.312 1.00 78.38 ? 400 PRO A O   1 
ATOM   3007  C CB  . PRO A 1 400 ? 134.605 75.025  109.179 1.00 78.38 ? 400 PRO A CB  1 
ATOM   3008  C CG  . PRO A 1 400 ? 134.183 75.044  110.609 1.00 78.38 ? 400 PRO A CG  1 
ATOM   3009  C CD  . PRO A 1 400 ? 133.047 76.004  110.688 1.00 78.38 ? 400 PRO A CD  1 
ATOM   3010  N N   . GLN A 1 401 ? 132.529 76.098  107.091 1.00 78.82 ? 401 GLN A N   1 
ATOM   3011  C CA  . GLN A 1 401 ? 131.867 76.137  105.792 1.00 78.82 ? 401 GLN A CA  1 
ATOM   3012  C C   . GLN A 1 401 ? 131.190 77.490  105.652 1.00 78.82 ? 401 GLN A C   1 
ATOM   3013  O O   . GLN A 1 401 ? 130.074 77.689  106.134 1.00 78.82 ? 401 GLN A O   1 
ATOM   3014  C CB  . GLN A 1 401 ? 130.854 75.009  105.664 1.00 78.82 ? 401 GLN A CB  1 
ATOM   3015  C CG  . GLN A 1 401 ? 131.434 73.620  105.813 1.00 78.82 ? 401 GLN A CG  1 
ATOM   3016  C CD  . GLN A 1 401 ? 130.364 72.556  105.781 1.00 78.82 ? 401 GLN A CD  1 
ATOM   3017  O OE1 . GLN A 1 401 ? 130.638 71.376  105.989 1.00 78.82 ? 401 GLN A OE1 1 
ATOM   3018  N NE2 . GLN A 1 401 ? 129.132 72.969  105.516 1.00 78.82 ? 401 GLN A NE2 1 
ATOM   3019  N N   . SER A 1 402 ? 131.858 78.419  104.978 1.00 75.75 ? 402 SER A N   1 
ATOM   3020  C CA  . SER A 1 402 ? 131.375 79.783  104.846 1.00 75.75 ? 402 SER A CA  1 
ATOM   3021  C C   . SER A 1 402 ? 131.543 80.244  103.410 1.00 75.75 ? 402 SER A C   1 
ATOM   3022  O O   . SER A 1 402 ? 132.558 79.951  102.774 1.00 75.75 ? 402 SER A O   1 
ATOM   3023  C CB  . SER A 1 402 ? 132.123 80.713  105.796 1.00 75.75 ? 402 SER A CB  1 
ATOM   3024  O OG  . SER A 1 402 ? 133.505 80.699  105.506 1.00 75.75 ? 402 SER A OG  1 
ATOM   3025  N N   . THR A 1 403 ? 130.540 80.966  102.903 1.00 70.53 ? 403 THR A N   1 
ATOM   3026  C CA  . THR A 1 403 ? 130.503 81.347  101.498 1.00 70.53 ? 403 THR A CA  1 
ATOM   3027  C C   . THR A 1 403 ? 130.174 82.819  101.288 1.00 70.53 ? 403 THR A C   1 
ATOM   3028  O O   . THR A 1 403 ? 130.034 83.248  100.139 1.00 70.53 ? 403 THR A O   1 
ATOM   3029  C CB  . THR A 1 403 ? 129.476 80.501  100.738 1.00 70.53 ? 403 THR A CB  1 
ATOM   3030  O OG1 . THR A 1 403 ? 128.164 80.802  101.224 1.00 70.53 ? 403 THR A OG1 1 
ATOM   3031  C CG2 . THR A 1 403 ? 129.751 79.029  100.921 1.00 70.53 ? 403 THR A CG2 1 
ATOM   3032  N N   . HIS A 1 404 ? 130.064 83.607  102.355 1.00 62.12 ? 404 HIS A N   1 
ATOM   3033  C CA  . HIS A 1 404 ? 129.299 84.843  102.314 1.00 62.12 ? 404 HIS A CA  1 
ATOM   3034  C C   . HIS A 1 404 ? 130.110 86.119  102.457 1.00 62.12 ? 404 HIS A C   1 
ATOM   3035  O O   . HIS A 1 404 ? 129.528 87.204  102.398 1.00 62.12 ? 404 HIS A O   1 
ATOM   3036  C CB  . HIS A 1 404 ? 128.222 84.806  103.397 1.00 62.12 ? 404 HIS A CB  1 
ATOM   3037  C CG  . HIS A 1 404 ? 127.052 83.958  103.033 1.00 62.12 ? 404 HIS A CG  1 
ATOM   3038  N ND1 . HIS A 1 404 ? 126.867 83.466  101.760 1.00 62.12 ? 404 HIS A ND1 1 
ATOM   3039  C CD2 . HIS A 1 404 ? 126.007 83.512  103.766 1.00 62.12 ? 404 HIS A CD2 1 
ATOM   3040  C CE1 . HIS A 1 404 ? 125.756 82.754  101.724 1.00 62.12 ? 404 HIS A CE1 1 
ATOM   3041  N NE2 . HIS A 1 404 ? 125.215 82.767  102.928 1.00 62.12 ? 404 HIS A NE2 1 
ATOM   3042  N N   . ALA A 1 405 ? 131.423 86.040  102.631 1.00 60.44 ? 405 ALA A N   1 
ATOM   3043  C CA  . ALA A 1 405 ? 132.196 87.271  102.713 1.00 60.44 ? 405 ALA A CA  1 
ATOM   3044  C C   . ALA A 1 405 ? 132.366 87.897  101.340 1.00 60.44 ? 405 ALA A C   1 
ATOM   3045  O O   . ALA A 1 405 ? 131.888 89.005  101.089 1.00 60.44 ? 405 ALA A O   1 
ATOM   3046  C CB  . ALA A 1 405 ? 133.558 87.005  103.350 1.00 60.44 ? 405 ALA A CB  1 
ATOM   3047  N N   . TYR A 1 406 ? 133.023 87.190  100.433 1.00 64.45 ? 406 TYR A N   1 
ATOM   3048  C CA  . TYR A 1 406 ? 133.436 87.738  99.153  1.00 64.45 ? 406 TYR A CA  1 
ATOM   3049  C C   . TYR A 1 406 ? 132.397 87.471  98.079  1.00 64.45 ? 406 TYR A C   1 
ATOM   3050  O O   . TYR A 1 406 ? 131.667 86.479  98.137  1.00 64.45 ? 406 TYR A O   1 
ATOM   3051  C CB  . TYR A 1 406 ? 134.772 87.144  98.733  1.00 64.45 ? 406 TYR A CB  1 
ATOM   3052  C CG  . TYR A 1 406 ? 135.772 87.162  99.843  1.00 64.45 ? 406 TYR A CG  1 
ATOM   3053  C CD1 . TYR A 1 406 ? 136.545 88.282  100.080 1.00 64.45 ? 406 TYR A CD1 1 
ATOM   3054  C CD2 . TYR A 1 406 ? 135.930 86.069  100.674 1.00 64.45 ? 406 TYR A CD2 1 
ATOM   3055  C CE1 . TYR A 1 406 ? 137.460 88.310  101.103 1.00 64.45 ? 406 TYR A CE1 1 
ATOM   3056  C CE2 . TYR A 1 406 ? 136.840 86.090  101.701 1.00 64.45 ? 406 TYR A CE2 1 
ATOM   3057  C CZ  . TYR A 1 406 ? 137.605 87.214  101.910 1.00 64.45 ? 406 TYR A CZ  1 
ATOM   3058  O OH  . TYR A 1 406 ? 138.520 87.253  102.931 1.00 64.45 ? 406 TYR A OH  1 
ATOM   3059  N N   . VAL A 1 407 ? 132.321 88.379  97.105  1.00 60.40 ? 407 VAL A N   1 
ATOM   3060  C CA  . VAL A 1 407 ? 131.469 88.216  95.940  1.00 60.40 ? 407 VAL A CA  1 
ATOM   3061  C C   . VAL A 1 407 ? 132.258 88.270  94.637  1.00 60.40 ? 407 VAL A C   1 
ATOM   3062  O O   . VAL A 1 407 ? 131.995 87.489  93.724  1.00 60.40 ? 407 VAL A O   1 
ATOM   3063  C CB  . VAL A 1 407 ? 130.314 89.237  95.932  1.00 60.40 ? 407 VAL A CB  1 
ATOM   3064  C CG1 . VAL A 1 407 ? 129.502 89.110  97.199  1.00 60.40 ? 407 VAL A CG1 1 
ATOM   3065  C CG2 . VAL A 1 407 ? 130.841 90.627  95.831  1.00 60.40 ? 407 VAL A CG2 1 
ATOM   3066  N N   . TRP A 1 408 ? 133.231 89.171  94.524  1.00 56.80 ? 408 TRP A N   1 
ATOM   3067  C CA  . TRP A 1 408 ? 133.978 89.325  93.285  1.00 56.80 ? 408 TRP A CA  1 
ATOM   3068  C C   . TRP A 1 408 ? 135.453 89.524  93.576  1.00 56.80 ? 408 TRP A C   1 
ATOM   3069  O O   . TRP A 1 408 ? 135.821 90.234  94.513  1.00 56.80 ? 408 TRP A O   1 
ATOM   3070  C CB  . TRP A 1 408 ? 133.457 90.508  92.460  1.00 56.80 ? 408 TRP A CB  1 
ATOM   3071  C CG  . TRP A 1 408 ? 132.062 90.331  92.052  1.00 56.80 ? 408 TRP A CG  1 
ATOM   3072  C CD1 . TRP A 1 408 ? 131.553 89.273  91.401  1.00 56.80 ? 408 TRP A CD1 1 
ATOM   3073  C CD2 . TRP A 1 408 ? 130.974 91.225  92.283  1.00 56.80 ? 408 TRP A CD2 1 
ATOM   3074  N NE1 . TRP A 1 408 ? 130.213 89.436  91.201  1.00 56.80 ? 408 TRP A NE1 1 
ATOM   3075  C CE2 . TRP A 1 408 ? 129.832 90.632  91.739  1.00 56.80 ? 408 TRP A CE2 1 
ATOM   3076  C CE3 . TRP A 1 408 ? 130.856 92.469  92.890  1.00 56.80 ? 408 TRP A CE3 1 
ATOM   3077  C CZ2 . TRP A 1 408 ? 128.585 91.235  91.784  1.00 56.80 ? 408 TRP A CZ2 1 
ATOM   3078  C CZ3 . TRP A 1 408 ? 129.615 93.063  92.938  1.00 56.80 ? 408 TRP A CZ3 1 
ATOM   3079  C CH2 . TRP A 1 408 ? 128.498 92.449  92.387  1.00 56.80 ? 408 TRP A CH2 1 
ATOM   3080  N N   . ILE A 1 409 ? 136.292 88.903  92.756  1.00 62.58 ? 409 ILE A N   1 
ATOM   3081  C CA  . ILE A 1 409 ? 137.729 89.139  92.774  1.00 62.58 ? 409 ILE A CA  1 
ATOM   3082  C C   . ILE A 1 409 ? 138.087 89.743  91.428  1.00 62.58 ? 409 ILE A C   1 
ATOM   3083  O O   . ILE A 1 409 ? 138.044 89.051  90.402  1.00 62.58 ? 409 ILE A O   1 
ATOM   3084  C CB  . ILE A 1 409 ? 138.530 87.856  93.025  1.00 62.58 ? 409 ILE A CB  1 
ATOM   3085  C CG1 . ILE A 1 409 ? 137.808 86.955  94.021  1.00 62.58 ? 409 ILE A CG1 1 
ATOM   3086  C CG2 . ILE A 1 409 ? 139.906 88.196  93.538  1.00 62.58 ? 409 ILE A CG2 1 
ATOM   3087  C CD1 . ILE A 1 409 ? 137.710 87.545  95.398  1.00 62.58 ? 409 ILE A CD1 1 
ATOM   3088  N N   . SER A 1 410 ? 138.427 91.027  91.412  1.00 65.10 ? 410 SER A N   1 
ATOM   3089  C CA  . SER A 1 410 ? 138.627 91.726  90.155  1.00 65.10 ? 410 SER A CA  1 
ATOM   3090  C C   . SER A 1 410 ? 140.096 92.041  89.936  1.00 65.10 ? 410 SER A C   1 
ATOM   3091  O O   . SER A 1 410 ? 140.810 92.429  90.868  1.00 65.10 ? 410 SER A O   1 
ATOM   3092  C CB  . SER A 1 410 ? 137.806 93.006  90.110  1.00 65.10 ? 410 SER A CB  1 
ATOM   3093  O OG  . SER A 1 410 ? 137.995 93.678  88.886  1.00 65.10 ? 410 SER A OG  1 
ATOM   3094  N N   . LEU A 1 411 ? 140.525 91.885  88.690  1.00 68.18 ? 411 LEU A N   1 
ATOM   3095  C CA  . LEU A 1 411 ? 141.898 92.084  88.266  1.00 68.18 ? 411 LEU A CA  1 
ATOM   3096  C C   . LEU A 1 411 ? 141.947 93.092  87.129  1.00 68.18 ? 411 LEU A C   1 
ATOM   3097  O O   . LEU A 1 411 ? 141.008 93.212  86.341  1.00 68.18 ? 411 LEU A O   1 
ATOM   3098  C CB  . LEU A 1 411 ? 142.521 90.773  87.793  1.00 68.18 ? 411 LEU A CB  1 
ATOM   3099  C CG  . LEU A 1 411 ? 142.559 89.614  88.781  1.00 68.18 ? 411 LEU A CG  1 
ATOM   3100  C CD1 . LEU A 1 411 ? 141.266 88.825  88.754  1.00 68.18 ? 411 LEU A CD1 1 
ATOM   3101  C CD2 . LEU A 1 411 ? 143.724 88.729  88.446  1.00 68.18 ? 411 LEU A CD2 1 
ATOM   3102  N N   . ALA A 1 412 ? 143.050 93.829  87.065  1.00 71.79 ? 412 ALA A N   1 
ATOM   3103  C CA  . ALA A 1 412 ? 143.386 94.664  85.924  1.00 71.79 ? 412 ALA A CA  1 
ATOM   3104  C C   . ALA A 1 412 ? 144.805 95.149  86.119  1.00 71.79 ? 412 ALA A C   1 
ATOM   3105  O O   . ALA A 1 412 ? 145.156 95.598  87.208  1.00 71.79 ? 412 ALA A O   1 
ATOM   3106  C CB  . ALA A 1 412 ? 142.442 95.859  85.784  1.00 71.79 ? 412 ALA A CB  1 
ATOM   3107  N N   . TYR A 1 413 ? 145.614 95.061  85.074  1.00 81.27 ? 413 TYR A N   1 
ATOM   3108  C CA  . TYR A 1 413 ? 146.996 95.511  85.136  1.00 81.27 ? 413 TYR A CA  1 
ATOM   3109  C C   . TYR A 1 413 ? 147.114 96.814  84.365  1.00 81.27 ? 413 TYR A C   1 
ATOM   3110  O O   . TYR A 1 413 ? 146.909 96.839  83.148  1.00 81.27 ? 413 TYR A O   1 
ATOM   3111  C CB  . TYR A 1 413 ? 147.953 94.466  84.573  1.00 81.27 ? 413 TYR A CB  1 
ATOM   3112  C CG  . TYR A 1 413 ? 149.332 94.534  85.182  1.00 81.27 ? 413 TYR A CG  1 
ATOM   3113  C CD1 . TYR A 1 413 ? 150.180 95.590  84.905  1.00 81.27 ? 413 TYR A CD1 1 
ATOM   3114  C CD2 . TYR A 1 413 ? 149.786 93.540  86.036  1.00 81.27 ? 413 TYR A CD2 1 
ATOM   3115  C CE1 . TYR A 1 413 ? 151.441 95.657  85.461  1.00 81.27 ? 413 TYR A CE1 1 
ATOM   3116  C CE2 . TYR A 1 413 ? 151.046 93.598  86.596  1.00 81.27 ? 413 TYR A CE2 1 
ATOM   3117  C CZ  . TYR A 1 413 ? 151.866 94.659  86.305  1.00 81.27 ? 413 TYR A CZ  1 
ATOM   3118  O OH  . TYR A 1 413 ? 153.120 94.721  86.856  1.00 81.27 ? 413 TYR A OH  1 
ATOM   3119  N N   . LYS A 1 414 ? 147.440 97.885  85.071  1.00 80.04 ? 414 LYS A N   1 
ATOM   3120  C CA  . LYS A 1 414 ? 147.620 99.194  84.474  1.00 80.04 ? 414 LYS A CA  1 
ATOM   3121  C C   . LYS A 1 414 ? 149.107 99.457  84.305  1.00 80.04 ? 414 LYS A C   1 
ATOM   3122  O O   . LYS A 1 414 ? 149.933 98.560  84.469  1.00 80.04 ? 414 LYS A O   1 
ATOM   3123  C CB  . LYS A 1 414 ? 146.917 100.265 85.307  1.00 80.04 ? 414 LYS A CB  1 
ATOM   3124  C CG  . LYS A 1 414 ? 145.417 100.256 85.074  1.00 80.04 ? 414 LYS A CG  1 
ATOM   3125  C CD  . LYS A 1 414 ? 144.651 101.142 86.027  1.00 80.04 ? 414 LYS A CD  1 
ATOM   3126  C CE  . LYS A 1 414 ? 143.163 101.074 85.715  1.00 80.04 ? 414 LYS A CE  1 
ATOM   3127  N NZ  . LYS A 1 414 ? 142.320 101.716 86.757  1.00 80.04 ? 414 LYS A NZ  1 
ATOM   3128  N N   . LYS A 1 415 ? 149.443 100.700 83.956  1.00 89.21 ? 415 LYS A N   1 
ATOM   3129  C CA  . LYS A 1 415 ? 150.778 100.986 83.440  1.00 89.21 ? 415 LYS A CA  1 
ATOM   3130  C C   . LYS A 1 415 ? 151.866 100.643 84.452  1.00 89.21 ? 415 LYS A C   1 
ATOM   3131  O O   . LYS A 1 415 ? 153.017 100.398 84.074  1.00 89.21 ? 415 LYS A O   1 
ATOM   3132  C CB  . LYS A 1 415 ? 150.871 102.453 83.020  1.00 89.21 ? 415 LYS A CB  1 
ATOM   3133  C CG  . LYS A 1 415 ? 152.129 102.808 82.232  1.00 89.21 ? 415 LYS A CG  1 
ATOM   3134  C CD  . LYS A 1 415 ? 153.235 103.357 83.114  1.00 89.21 ? 415 LYS A CD  1 
ATOM   3135  C CE  . LYS A 1 415 ? 152.898 104.738 83.639  1.00 89.21 ? 415 LYS A CE  1 
ATOM   3136  N NZ  . LYS A 1 415 ? 153.999 105.280 84.485  1.00 89.21 ? 415 LYS A NZ  1 
ATOM   3137  N N   . THR A 1 416 ? 151.525 100.599 85.738  1.00 84.73 ? 416 THR A N   1 
ATOM   3138  C CA  . THR A 1 416 ? 152.496 100.243 86.765  1.00 84.73 ? 416 THR A CA  1 
ATOM   3139  C C   . THR A 1 416 ? 152.177 98.931  87.461  1.00 84.73 ? 416 THR A C   1 
ATOM   3140  O O   . THR A 1 416 ? 153.011 98.024  87.478  1.00 84.73 ? 416 THR A O   1 
ATOM   3141  C CB  . THR A 1 416 ? 152.601 101.358 87.807  1.00 84.73 ? 416 THR A CB  1 
ATOM   3142  O OG1 . THR A 1 416 ? 153.063 102.554 87.171  1.00 84.73 ? 416 THR A OG1 1 
ATOM   3143  C CG2 . THR A 1 416 ? 153.580 100.958 88.895  1.00 84.73 ? 416 THR A CG2 1 
ATOM   3144  N N   . GLY A 1 417 ? 150.987 98.796  88.040  1.00 80.30 ? 417 GLY A N   1 
ATOM   3145  C CA  . GLY A 1 417 ? 150.660 97.621  88.810  1.00 80.30 ? 417 GLY A CA  1 
ATOM   3146  C C   . GLY A 1 417 ? 149.259 97.103  88.569  1.00 80.30 ? 417 GLY A C   1 
ATOM   3147  O O   . GLY A 1 417 ? 148.456 97.709  87.854  1.00 80.30 ? 417 GLY A O   1 
ATOM   3148  N N   . PRO A 1 418 ? 148.945 95.956  89.165  1.00 74.39 ? 418 PRO A N   1 
ATOM   3149  C CA  . PRO A 1 418 ? 147.603 95.392  89.029  1.00 74.39 ? 418 PRO A CA  1 
ATOM   3150  C C   . PRO A 1 418 ? 146.580 96.200  89.803  1.00 74.39 ? 418 PRO A C   1 
ATOM   3151  O O   . PRO A 1 418 ? 146.891 96.989  90.695  1.00 74.39 ? 418 PRO A O   1 
ATOM   3152  C CB  . PRO A 1 418 ? 147.740 93.984  89.609  1.00 74.39 ? 418 PRO A CB  1 
ATOM   3153  C CG  . PRO A 1 418 ? 149.192 93.715  89.643  1.00 74.39 ? 418 PRO A CG  1 
ATOM   3154  C CD  . PRO A 1 418 ? 149.855 95.033  89.856  1.00 74.39 ? 418 PRO A CD  1 
ATOM   3155  N N   . TYR A 1 419 ? 145.327 95.970  89.455  1.00 67.83 ? 419 TYR A N   1 
ATOM   3156  C CA  . TYR A 1 419 ? 144.198 96.629  90.096  1.00 67.83 ? 419 TYR A CA  1 
ATOM   3157  C C   . TYR A 1 419 ? 143.306 95.508  90.597  1.00 67.83 ? 419 TYR A C   1 
ATOM   3158  O O   . TYR A 1 419 ? 142.288 95.184  89.987  1.00 67.83 ? 419 TYR A O   1 
ATOM   3159  C CB  . TYR A 1 419 ? 143.496 97.527  89.104  1.00 67.83 ? 419 TYR A CB  1 
ATOM   3160  C CG  . TYR A 1 419 ? 142.510 98.503  89.671  1.00 67.83 ? 419 TYR A CG  1 
ATOM   3161  C CD1 . TYR A 1 419 ? 141.196 98.130  89.916  1.00 67.83 ? 419 TYR A CD1 1 
ATOM   3162  C CD2 . TYR A 1 419 ? 142.879 99.814  89.922  1.00 67.83 ? 419 TYR A CD2 1 
ATOM   3163  C CE1 . TYR A 1 419 ? 140.283 99.037  90.419  1.00 67.83 ? 419 TYR A CE1 1 
ATOM   3164  C CE2 . TYR A 1 419 ? 141.978 100.721 90.420  1.00 67.83 ? 419 TYR A CE2 1 
ATOM   3165  C CZ  . TYR A 1 419 ? 140.683 100.330 90.669  1.00 67.83 ? 419 TYR A CZ  1 
ATOM   3166  O OH  . TYR A 1 419 ? 139.793 101.245 91.173  1.00 67.83 ? 419 TYR A OH  1 
ATOM   3167  N N   . ILE A 1 420 ? 143.678 94.942  91.737  1.00 63.88 ? 420 ILE A N   1 
ATOM   3168  C CA  . ILE A 1 420 ? 142.960 93.826  92.332  1.00 63.88 ? 420 ILE A CA  1 
ATOM   3169  C C   . ILE A 1 420 ? 142.048 94.394  93.395  1.00 63.88 ? 420 ILE A C   1 
ATOM   3170  O O   . ILE A 1 420 ? 142.512 94.983  94.376  1.00 63.88 ? 420 ILE A O   1 
ATOM   3171  C CB  . ILE A 1 420 ? 143.913 92.787  92.933  1.00 63.88 ? 420 ILE A CB  1 
ATOM   3172  C CG1 . ILE A 1 420 ? 144.914 92.315  91.886  1.00 63.88 ? 420 ILE A CG1 1 
ATOM   3173  C CG2 . ILE A 1 420 ? 143.125 91.621  93.474  1.00 63.88 ? 420 ILE A CG2 1 
ATOM   3174  C CD1 . ILE A 1 420 ? 145.714 91.125  92.316  1.00 63.88 ? 420 ILE A CD1 1 
ATOM   3175  N N   . THR A 1 421 ? 140.755 94.233  93.199  1.00 57.39 ? 421 THR A N   1 
ATOM   3176  C CA  . THR A 1 421 ? 139.774 94.733  94.139  1.00 57.39 ? 421 THR A CA  1 
ATOM   3177  C C   . THR A 1 421 ? 138.913 93.585  94.628  1.00 57.39 ? 421 THR A C   1 
ATOM   3178  O O   . THR A 1 421 ? 138.399 92.790  93.831  1.00 57.39 ? 421 THR A O   1 
ATOM   3179  C CB  . THR A 1 421 ? 138.959 95.865  93.518  1.00 57.39 ? 421 THR A CB  1 
ATOM   3180  O OG1 . THR A 1 421 ? 137.729 96.053  94.228  1.00 57.39 ? 421 THR A OG1 1 
ATOM   3181  C CG2 . THR A 1 421 ? 138.756 95.662  92.050  1.00 57.39 ? 421 THR A CG2 1 
ATOM   3182  N N   . VAL A 1 422 ? 138.815 93.487  95.945  1.00 53.80 ? 422 VAL A N   1 
ATOM   3183  C CA  . VAL A 1 422 ? 138.202 92.359  96.626  1.00 53.80 ? 422 VAL A CA  1 
ATOM   3184  C C   . VAL A 1 422 ? 136.842 92.864  97.077  1.00 53.80 ? 422 VAL A C   1 
ATOM   3185  O O   . VAL A 1 422 ? 136.703 93.501  98.113  1.00 53.80 ? 422 VAL A O   1 
ATOM   3186  C CB  . VAL A 1 422 ? 139.058 91.868  97.789  1.00 53.80 ? 422 VAL A CB  1 
ATOM   3187  C CG1 . VAL A 1 422 ? 138.314 90.853  98.599  1.00 53.80 ? 422 VAL A CG1 1 
ATOM   3188  C CG2 . VAL A 1 422 ? 140.346 91.278  97.276  1.00 53.80 ? 422 VAL A CG2 1 
ATOM   3189  N N   . TYR A 1 423 ? 135.832 92.611  96.266  1.00 53.94 ? 423 TYR A N   1 
ATOM   3190  C CA  . TYR A 1 423 ? 134.507 93.081  96.607  1.00 53.94 ? 423 TYR A CA  1 
ATOM   3191  C C   . TYR A 1 423 ? 133.910 92.166  97.652  1.00 53.94 ? 423 TYR A C   1 
ATOM   3192  O O   . TYR A 1 423 ? 134.033 90.945  97.573  1.00 53.94 ? 423 TYR A O   1 
ATOM   3193  C CB  . TYR A 1 423 ? 133.632 93.130  95.364  1.00 53.94 ? 423 TYR A CB  1 
ATOM   3194  C CG  . TYR A 1 423 ? 134.217 94.001  94.288  1.00 53.94 ? 423 TYR A CG  1 
ATOM   3195  C CD1 . TYR A 1 423 ? 135.219 93.542  93.461  1.00 53.94 ? 423 TYR A CD1 1 
ATOM   3196  C CD2 . TYR A 1 423 ? 133.794 95.294  94.127  1.00 53.94 ? 423 TYR A CD2 1 
ATOM   3197  C CE1 . TYR A 1 423 ? 135.752 94.340  92.497  1.00 53.94 ? 423 TYR A CE1 1 
ATOM   3198  C CE2 . TYR A 1 423 ? 134.319 96.100  93.167  1.00 53.94 ? 423 TYR A CE2 1 
ATOM   3199  C CZ  . TYR A 1 423 ? 135.303 95.624  92.355  1.00 53.94 ? 423 TYR A CZ  1 
ATOM   3200  O OH  . TYR A 1 423 ? 135.829 96.443  91.389  1.00 53.94 ? 423 TYR A OH  1 
ATOM   3201  N N   . THR A 1 424 ? 133.289 92.760  98.652  1.00 50.66 ? 424 THR A N   1 
ATOM   3202  C CA  . THR A 1 424 ? 132.690 92.008  99.731  1.00 50.66 ? 424 THR A CA  1 
ATOM   3203  C C   . THR A 1 424 ? 131.214 92.318  99.780  1.00 50.66 ? 424 THR A C   1 
ATOM   3204  O O   . THR A 1 424 ? 130.717 93.211  99.100  1.00 50.66 ? 424 THR A O   1 
ATOM   3205  C CB  . THR A 1 424 ? 133.326 92.340  101.079 1.00 50.66 ? 424 THR A CB  1 
ATOM   3206  O OG1 . THR A 1 424 ? 133.232 93.749  101.311 1.00 50.66 ? 424 THR A OG1 1 
ATOM   3207  C CG2 . THR A 1 424 ? 134.776 91.914  101.113 1.00 50.66 ? 424 THR A CG2 1 
ATOM   3208  N N   . ASN A 1 425 ? 130.515 91.554  100.589 1.00 49.04 ? 425 ASN A N   1 
ATOM   3209  C CA  . ASN A 1 425 ? 129.158 91.909  100.954 1.00 49.04 ? 425 ASN A CA  1 
ATOM   3210  C C   . ASN A 1 425 ? 129.238 92.440  102.367 1.00 49.04 ? 425 ASN A C   1 
ATOM   3211  O O   . ASN A 1 425 ? 129.356 91.654  103.317 1.00 49.04 ? 425 ASN A O   1 
ATOM   3212  C CB  . ASN A 1 425 ? 128.225 90.705  100.876 1.00 49.04 ? 425 ASN A CB  1 
ATOM   3213  C CG  . ASN A 1 425 ? 126.781 91.098  100.908 1.00 49.04 ? 425 ASN A CG  1 
ATOM   3214  O OD1 . ASN A 1 425 ? 126.451 92.276  100.880 1.00 49.04 ? 425 ASN A OD1 1 
ATOM   3215  N ND2 . ASN A 1 425 ? 125.901 90.112  100.960 1.00 49.04 ? 425 ASN A ND2 1 
ATOM   3216  N N   . PRO A 1 426 ? 129.230 93.754  102.567 1.00 48.17 ? 426 PRO A N   1 
ATOM   3217  C CA  . PRO A 1 426 ? 129.205 94.281  103.931 1.00 48.17 ? 426 PRO A CA  1 
ATOM   3218  C C   . PRO A 1 426 ? 127.955 93.901  104.691 1.00 48.17 ? 426 PRO A C   1 
ATOM   3219  O O   . PRO A 1 426 ? 127.877 94.180  105.888 1.00 48.17 ? 426 PRO A O   1 
ATOM   3220  C CB  . PRO A 1 426 ? 129.295 95.792  103.717 1.00 48.17 ? 426 PRO A CB  1 
ATOM   3221  C CG  . PRO A 1 426 ? 128.765 96.003  102.359 1.00 48.17 ? 426 PRO A CG  1 
ATOM   3222  C CD  . PRO A 1 426 ? 129.200 94.826  101.567 1.00 48.17 ? 426 PRO A CD  1 
ATOM   3223  N N   . GLY A 1 427 ? 126.981 93.279  104.043 1.00 49.08 ? 427 GLY A N   1 
ATOM   3224  C CA  . GLY A 1 427 ? 125.791 92.820  104.720 1.00 49.08 ? 427 GLY A CA  1 
ATOM   3225  C C   . GLY A 1 427 ? 125.763 91.316  104.872 1.00 49.08 ? 427 GLY A C   1 
ATOM   3226  O O   . GLY A 1 427 ? 124.695 90.720  105.022 1.00 49.08 ? 427 GLY A O   1 
ATOM   3227  N N   . ALA A 1 428 ? 126.940 90.691  104.824 1.00 51.53 ? 428 ALA A N   1 
ATOM   3228  C CA  . ALA A 1 428 ? 127.014 89.248  104.998 1.00 51.53 ? 428 ALA A CA  1 
ATOM   3229  C C   . ALA A 1 428 ? 126.426 88.822  106.327 1.00 51.53 ? 428 ALA A C   1 
ATOM   3230  O O   . ALA A 1 428 ? 125.800 87.764  106.419 1.00 51.53 ? 428 ALA A O   1 
ATOM   3231  C CB  . ALA A 1 428 ? 128.459 88.782  104.899 1.00 51.53 ? 428 ALA A CB  1 
ATOM   3232  N N   . SER A 1 429 ? 126.613 89.632  107.366 1.00 49.87 ? 429 SER A N   1 
ATOM   3233  C CA  . SER A 1 429 ? 126.049 89.309  108.667 1.00 49.87 ? 429 SER A CA  1 
ATOM   3234  C C   . SER A 1 429 ? 124.541 89.162  108.600 1.00 49.87 ? 429 SER A C   1 
ATOM   3235  O O   . SER A 1 429 ? 123.951 88.483  109.443 1.00 49.87 ? 429 SER A O   1 
ATOM   3236  C CB  . SER A 1 429 ? 126.443 90.376  109.682 1.00 49.87 ? 429 SER A CB  1 
ATOM   3237  O OG  . SER A 1 429 ? 125.911 91.629  109.319 1.00 49.87 ? 429 SER A OG  1 
ATOM   3238  N N   . ILE A 1 430 ? 123.897 89.787  107.614 1.00 49.15 ? 430 ILE A N   1 
ATOM   3239  C CA  . ILE A 1 430 ? 122.467 89.589  107.452 1.00 49.15 ? 430 ILE A CA  1 
ATOM   3240  C C   . ILE A 1 430 ? 122.177 88.190  106.938 1.00 49.15 ? 430 ILE A C   1 
ATOM   3241  O O   . ILE A 1 430 ? 121.087 87.655  107.167 1.00 49.15 ? 430 ILE A O   1 
ATOM   3242  C CB  . ILE A 1 430 ? 121.891 90.649  106.503 1.00 49.15 ? 430 ILE A CB  1 
ATOM   3243  C CG1 . ILE A 1 430 ? 122.314 92.038  106.957 1.00 49.15 ? 430 ILE A CG1 1 
ATOM   3244  C CG2 . ILE A 1 430 ? 120.384 90.588  106.496 1.00 49.15 ? 430 ILE A CG2 1 
ATOM   3245  C CD1 . ILE A 1 430 ? 122.106 93.104  105.924 1.00 49.15 ? 430 ILE A CD1 1 
ATOM   3246  N N   . LEU A 1 431 ? 123.142 87.571  106.262 1.00 52.53 ? 431 LEU A N   1 
ATOM   3247  C CA  . LEU A 1 431 ? 122.975 86.216  105.760 1.00 52.53 ? 431 LEU A CA  1 
ATOM   3248  C C   . LEU A 1 431 ? 123.371 85.166  106.784 1.00 52.53 ? 431 LEU A C   1 
ATOM   3249  O O   . LEU A 1 431 ? 123.706 84.041  106.403 1.00 52.53 ? 431 LEU A O   1 
ATOM   3250  C CB  . LEU A 1 431 ? 123.794 86.029  104.485 1.00 52.53 ? 431 LEU A CB  1 
ATOM   3251  C CG  . LEU A 1 431 ? 123.530 87.068  103.396 1.00 52.53 ? 431 LEU A CG  1 
ATOM   3252  C CD1 . LEU A 1 431 ? 124.245 86.701  102.123 1.00 52.53 ? 431 LEU A CD1 1 
ATOM   3253  C CD2 . LEU A 1 431 ? 122.047 87.205  103.144 1.00 52.53 ? 431 LEU A CD2 1 
ATOM   3254  N N   . GLU A 1 432 ? 123.365 85.515  108.064 1.00 54.69 ? 432 GLU A N   1 
ATOM   3255  C CA  . GLU A 1 432 ? 123.699 84.584  109.127 1.00 54.69 ? 432 GLU A CA  1 
ATOM   3256  C C   . GLU A 1 432 ? 122.684 84.678  110.256 1.00 54.69 ? 432 GLU A C   1 
ATOM   3257  O O   . GLU A 1 432 ? 121.490 84.836  110.014 1.00 54.69 ? 432 GLU A O   1 
ATOM   3258  C CB  . GLU A 1 432 ? 125.102 84.858  109.654 1.00 54.69 ? 432 GLU A CB  1 
ATOM   3259  C CG  . GLU A 1 432 ? 126.157 84.857  108.584 1.00 54.69 ? 432 GLU A CG  1 
ATOM   3260  C CD  . GLU A 1 432 ? 126.327 83.496  107.956 1.00 54.69 ? 432 GLU A CD  1 
ATOM   3261  O OE1 . GLU A 1 432 ? 125.970 82.493  108.603 1.00 54.69 ? 432 GLU A OE1 1 
ATOM   3262  O OE2 . GLU A 1 432 ? 126.814 83.422  106.811 1.00 54.69 ? 432 GLU A OE2 1 
ATOM   3263  N N   . SER B 1 23  ? 90.567  104.443 102.262 1.00 57.96 ? 23  SER B N   1 
ATOM   3264  C CA  . SER B 1 23  ? 90.586  105.274 103.459 1.00 57.96 ? 23  SER B CA  1 
ATOM   3265  C C   . SER B 1 23  ? 91.382  104.602 104.562 1.00 57.96 ? 23  SER B C   1 
ATOM   3266  O O   . SER B 1 23  ? 90.953  103.592 105.113 1.00 57.96 ? 23  SER B O   1 
ATOM   3267  C CB  . SER B 1 23  ? 89.166  105.556 103.943 1.00 57.96 ? 23  SER B CB  1 
ATOM   3268  O OG  . SER B 1 23  ? 88.596  104.396 104.523 1.00 57.96 ? 23  SER B OG  1 
ATOM   3269  N N   . PRO B 1 24  ? 92.540  105.160 104.890 1.00 51.72 ? 24  PRO B N   1 
ATOM   3270  C CA  . PRO B 1 24  ? 93.364  104.567 105.941 1.00 51.72 ? 24  PRO B CA  1 
ATOM   3271  C C   . PRO B 1 24  ? 92.714  104.734 107.303 1.00 51.72 ? 24  PRO B C   1 
ATOM   3272  O O   . PRO B 1 24  ? 91.753  105.484 107.482 1.00 51.72 ? 24  PRO B O   1 
ATOM   3273  C CB  . PRO B 1 24  ? 94.676  105.352 105.852 1.00 51.72 ? 24  PRO B CB  1 
ATOM   3274  C CG  . PRO B 1 24  ? 94.283  106.653 105.269 1.00 51.72 ? 24  PRO B CG  1 
ATOM   3275  C CD  . PRO B 1 24  ? 93.146  106.378 104.332 1.00 51.72 ? 24  PRO B CD  1 
ATOM   3276  N N   . SER B 1 25  ? 93.242  104.004 108.257 1.00 46.00 ? 25  SER B N   1 
ATOM   3277  C CA  . SER B 1 25  ? 92.880  104.171 109.651 1.00 46.00 ? 25  SER B CA  1 
ATOM   3278  C C   . SER B 1 25  ? 93.882  105.084 110.329 1.00 46.00 ? 25  SER B C   1 
ATOM   3279  O O   . SER B 1 25  ? 95.031  105.189 109.893 1.00 46.00 ? 25  SER B O   1 
ATOM   3280  C CB  . SER B 1 25  ? 92.852  102.821 110.349 1.00 46.00 ? 25  SER B CB  1 
ATOM   3281  O OG  . SER B 1 25  ? 94.158  102.290 110.441 1.00 46.00 ? 25  SER B OG  1 
ATOM   3282  N N   . PRO B 1 26  ? 93.475  105.767 111.392 1.00 42.85 ? 26  PRO B N   1 
ATOM   3283  C CA  . PRO B 1 26  ? 94.371  106.718 112.053 1.00 42.85 ? 26  PRO B CA  1 
ATOM   3284  C C   . PRO B 1 26  ? 95.751  106.172 112.341 1.00 42.85 ? 26  PRO B C   1 
ATOM   3285  O O   . PRO B 1 26  ? 96.731  106.877 112.125 1.00 42.85 ? 26  PRO B O   1 
ATOM   3286  C CB  . PRO B 1 26  ? 93.622  107.046 113.341 1.00 42.85 ? 26  PRO B CB  1 
ATOM   3287  C CG  . PRO B 1 26  ? 92.218  106.953 112.950 1.00 42.85 ? 26  PRO B CG  1 
ATOM   3288  C CD  . PRO B 1 26  ? 92.120  105.824 111.960 1.00 42.85 ? 26  PRO B CD  1 
ATOM   3289  N N   . TRP B 1 27  ? 95.872  104.932 112.801 1.00 42.43 ? 27  TRP B N   1 
ATOM   3290  C CA  . TRP B 1 27  ? 97.211  104.434 113.081 1.00 42.43 ? 27  TRP B CA  1 
ATOM   3291  C C   . TRP B 1 27  ? 97.980  104.179 111.794 1.00 42.43 ? 27  TRP B C   1 
ATOM   3292  O O   . TRP B 1 27  ? 99.179  104.451 111.727 1.00 42.43 ? 27  TRP B O   1 
ATOM   3293  C CB  . TRP B 1 27  ? 97.164  103.183 113.958 1.00 42.43 ? 27  TRP B CB  1 
ATOM   3294  C CG  . TRP B 1 27  ? 96.224  102.135 113.545 1.00 42.43 ? 27  TRP B CG  1 
ATOM   3295  C CD1 . TRP B 1 27  ? 96.523  100.989 112.891 1.00 42.43 ? 27  TRP B CD1 1 
ATOM   3296  C CD2 . TRP B 1 27  ? 94.828  102.102 113.796 1.00 42.43 ? 27  TRP B CD2 1 
ATOM   3297  N NE1 . TRP B 1 27  ? 95.394  100.248 112.695 1.00 42.43 ? 27  TRP B NE1 1 
ATOM   3298  C CE2 . TRP B 1 27  ? 94.337  100.913 113.248 1.00 42.43 ? 27  TRP B CE2 1 
ATOM   3299  C CE3 . TRP B 1 27  ? 93.941  102.970 114.426 1.00 42.43 ? 27  TRP B CE3 1 
ATOM   3300  C CZ2 . TRP B 1 27  ? 93.003  100.568 113.306 1.00 42.43 ? 27  TRP B CZ2 1 
ATOM   3301  C CZ3 . TRP B 1 27  ? 92.618  102.630 114.481 1.00 42.43 ? 27  TRP B CZ3 1 
ATOM   3302  C CH2 . TRP B 1 27  ? 92.158  101.441 113.925 1.00 42.43 ? 27  TRP B CH2 1 
ATOM   3303  N N   . ASP B 1 28  ? 97.307  103.697 110.751 1.00 46.59 ? 28  ASP B N   1 
ATOM   3304  C CA  . ASP B 1 28  ? 97.979  103.487 109.475 1.00 46.59 ? 28  ASP B CA  1 
ATOM   3305  C C   . ASP B 1 28  ? 98.481  104.801 108.901 1.00 46.59 ? 28  ASP B C   1 
ATOM   3306  O O   . ASP B 1 28  ? 99.673  104.962 108.612 1.00 46.59 ? 28  ASP B O   1 
ATOM   3307  C CB  . ASP B 1 28  ? 97.026  102.816 108.496 1.00 46.59 ? 28  ASP B CB  1 
ATOM   3308  C CG  . ASP B 1 28  ? 96.561  101.476 108.976 1.00 46.59 ? 28  ASP B CG  1 
ATOM   3309  O OD1 . ASP B 1 28  ? 97.416  100.670 109.390 1.00 46.59 ? 28  ASP B OD1 1 
ATOM   3310  O OD2 . ASP B 1 28  ? 95.340  101.227 108.944 1.00 46.59 ? 28  ASP B OD2 1 
ATOM   3311  N N   . PHE B 1 29  ? 97.565  105.751 108.715 1.00 43.96 ? 29  PHE B N   1 
ATOM   3312  C CA  . PHE B 1 29  ? 97.931  107.066 108.208 1.00 43.96 ? 29  PHE B CA  1 
ATOM   3313  C C   . PHE B 1 29  ? 99.027  107.695 109.050 1.00 43.96 ? 29  PHE B C   1 
ATOM   3314  O O   . PHE B 1 29  ? 100.002 108.232 108.516 1.00 43.96 ? 29  PHE B O   1 
ATOM   3315  C CB  . PHE B 1 29  ? 96.694  107.957 108.185 1.00 43.96 ? 29  PHE B CB  1 
ATOM   3316  C CG  . PHE B 1 29  ? 96.864  109.217 107.398 1.00 43.96 ? 29  PHE B CG  1 
ATOM   3317  C CD1 . PHE B 1 29  ? 97.596  109.227 106.229 1.00 43.96 ? 29  PHE B CD1 1 
ATOM   3318  C CD2 . PHE B 1 29  ? 96.276  110.390 107.820 1.00 43.96 ? 29  PHE B CD2 1 
ATOM   3319  C CE1 . PHE B 1 29  ? 97.745  110.383 105.505 1.00 43.96 ? 29  PHE B CE1 1 
ATOM   3320  C CE2 . PHE B 1 29  ? 96.425  111.548 107.098 1.00 43.96 ? 29  PHE B CE2 1 
ATOM   3321  C CZ  . PHE B 1 29  ? 97.160  111.543 105.941 1.00 43.96 ? 29  PHE B CZ  1 
ATOM   3322  N N   . LEU B 1 30  ? 98.894  107.621 110.370 1.00 39.64 ? 30  LEU B N   1 
ATOM   3323  C CA  . LEU B 1 30  ? 99.849  108.277 111.244 1.00 39.64 ? 30  LEU B CA  1 
ATOM   3324  C C   . LEU B 1 30  ? 101.216 107.624 111.155 1.00 39.64 ? 30  LEU B C   1 
ATOM   3325  O O   . LEU B 1 30  ? 102.229 108.319 111.083 1.00 39.64 ? 30  LEU B O   1 
ATOM   3326  C CB  . LEU B 1 30  ? 99.320  108.273 112.670 1.00 39.64 ? 30  LEU B CB  1 
ATOM   3327  C CG  . LEU B 1 30  ? 98.238  109.323 112.915 1.00 39.64 ? 30  LEU B CG  1 
ATOM   3328  C CD1 . LEU B 1 30  ? 97.646  109.185 114.301 1.00 39.64 ? 30  LEU B CD1 1 
ATOM   3329  C CD2 . LEU B 1 30  ? 98.798  110.704 112.702 1.00 39.64 ? 30  LEU B CD2 1 
ATOM   3330  N N   . GLY B 1 31  ? 101.274 106.297 111.141 1.00 43.37 ? 31  GLY B N   1 
ATOM   3331  C CA  . GLY B 1 31  ? 102.544 105.638 110.920 1.00 43.37 ? 31  GLY B CA  1 
ATOM   3332  C C   . GLY B 1 31  ? 103.138 105.993 109.579 1.00 43.37 ? 31  GLY B C   1 
ATOM   3333  O O   . GLY B 1 31  ? 104.359 105.969 109.407 1.00 43.37 ? 31  GLY B O   1 
ATOM   3334  N N   . ARG B 1 32  ? 102.286 106.343 108.616 1.00 44.20 ? 32  ARG B N   1 
ATOM   3335  C CA  . ARG B 1 32  ? 102.791 106.782 107.323 1.00 44.20 ? 32  ARG B CA  1 
ATOM   3336  C C   . ARG B 1 32  ? 103.396 108.178 107.401 1.00 44.20 ? 32  ARG B C   1 
ATOM   3337  O O   . ARG B 1 32  ? 104.468 108.423 106.838 1.00 44.20 ? 32  ARG B O   1 
ATOM   3338  C CB  . ARG B 1 32  ? 101.673 106.736 106.289 1.00 44.20 ? 32  ARG B CB  1 
ATOM   3339  C CG  . ARG B 1 32  ? 101.238 105.337 105.951 1.00 44.20 ? 32  ARG B CG  1 
ATOM   3340  C CD  . ARG B 1 32  ? 100.927 105.214 104.498 1.00 44.20 ? 32  ARG B CD  1 
ATOM   3341  N NE  . ARG B 1 32  ? 99.620  105.769 104.204 1.00 44.20 ? 32  ARG B NE  1 
ATOM   3342  C CZ  . ARG B 1 32  ? 98.513  105.046 104.148 1.00 44.20 ? 32  ARG B CZ  1 
ATOM   3343  N NH1 . ARG B 1 32  ? 98.570  103.743 104.370 1.00 44.20 ? 32  ARG B NH1 1 
ATOM   3344  N NH2 . ARG B 1 32  ? 97.354  105.622 103.872 1.00 44.20 ? 32  ARG B NH2 1 
ATOM   3345  N N   . VAL B 1 33  ? 102.741 109.103 108.100 1.00 40.22 ? 33  VAL B N   1 
ATOM   3346  C CA  . VAL B 1 33  ? 103.148 110.503 108.030 1.00 40.22 ? 33  VAL B CA  1 
ATOM   3347  C C   . VAL B 1 33  ? 104.052 110.911 109.189 1.00 40.22 ? 33  VAL B C   1 
ATOM   3348  O O   . VAL B 1 33  ? 104.894 111.798 109.031 1.00 40.22 ? 33  VAL B O   1 
ATOM   3349  C CB  . VAL B 1 33  ? 101.926 111.437 107.947 1.00 40.22 ? 33  VAL B CB  1 
ATOM   3350  C CG1 . VAL B 1 33  ? 100.982 110.976 106.876 1.00 40.22 ? 33  VAL B CG1 1 
ATOM   3351  C CG2 . VAL B 1 33  ? 101.224 111.521 109.262 1.00 40.22 ? 33  VAL B CG2 1 
ATOM   3352  N N   . LEU B 1 34  ? 103.910 110.275 110.346 1.00 37.37 ? 34  LEU B N   1 
ATOM   3353  C CA  . LEU B 1 34  ? 104.610 110.759 111.528 1.00 37.37 ? 34  LEU B CA  1 
ATOM   3354  C C   . LEU B 1 34  ? 106.099 110.478 111.439 1.00 37.37 ? 34  LEU B C   1 
ATOM   3355  O O   . LEU B 1 34  ? 106.533 109.456 110.910 1.00 37.37 ? 34  LEU B O   1 
ATOM   3356  C CB  . LEU B 1 34  ? 104.056 110.118 112.797 1.00 37.37 ? 34  LEU B CB  1 
ATOM   3357  C CG  . LEU B 1 34  ? 102.675 110.552 113.279 1.00 37.37 ? 34  LEU B CG  1 
ATOM   3358  C CD1 . LEU B 1 34  ? 102.243 109.720 114.459 1.00 37.37 ? 34  LEU B CD1 1 
ATOM   3359  C CD2 . LEU B 1 34  ? 102.672 112.012 113.626 1.00 37.37 ? 34  LEU B CD2 1 
ATOM   3360  N N   . GLN B 1 35  ? 106.883 111.408 111.963 1.00 41.30 ? 35  GLN B N   1 
ATOM   3361  C CA  . GLN B 1 35  ? 108.306 111.208 112.165 1.00 41.30 ? 35  GLN B CA  1 
ATOM   3362  C C   . GLN B 1 35  ? 108.512 110.730 113.589 1.00 41.30 ? 35  GLN B C   1 
ATOM   3363  O O   . GLN B 1 35  ? 107.953 111.307 114.524 1.00 41.30 ? 35  GLN B O   1 
ATOM   3364  C CB  . GLN B 1 35  ? 109.092 112.496 111.925 1.00 41.30 ? 35  GLN B CB  1 
ATOM   3365  C CG  . GLN B 1 35  ? 108.675 113.271 110.700 1.00 41.30 ? 35  GLN B CG  1 
ATOM   3366  C CD  . GLN B 1 35  ? 109.155 112.629 109.431 1.00 41.30 ? 35  GLN B CD  1 
ATOM   3367  O OE1 . GLN B 1 35  ? 108.372 112.358 108.524 1.00 41.30 ? 35  GLN B OE1 1 
ATOM   3368  N NE2 . GLN B 1 35  ? 110.451 112.373 109.357 1.00 41.30 ? 35  GLN B NE2 1 
ATOM   3369  N N   . PHE B 1 36  ? 109.303 109.682 113.752 1.00 38.40 ? 36  PHE B N   1 
ATOM   3370  C CA  . PHE B 1 36  ? 109.540 109.077 115.050 1.00 38.40 ? 36  PHE B CA  1 
ATOM   3371  C C   . PHE B 1 36  ? 110.941 109.414 115.524 1.00 38.40 ? 36  PHE B C   1 
ATOM   3372  O O   . PHE B 1 36  ? 111.900 109.319 114.758 1.00 38.40 ? 36  PHE B O   1 
ATOM   3373  C CB  . PHE B 1 36  ? 109.355 107.567 114.981 1.00 38.40 ? 36  PHE B CB  1 
ATOM   3374  C CG  . PHE B 1 36  ? 107.939 107.151 114.786 1.00 38.40 ? 36  PHE B CG  1 
ATOM   3375  C CD1 . PHE B 1 36  ? 107.409 107.041 113.528 1.00 38.40 ? 36  PHE B CD1 1 
ATOM   3376  C CD2 . PHE B 1 36  ? 107.133 106.881 115.865 1.00 38.40 ? 36  PHE B CD2 1 
ATOM   3377  C CE1 . PHE B 1 36  ? 106.106 106.668 113.353 1.00 38.40 ? 36  PHE B CE1 1 
ATOM   3378  C CE2 . PHE B 1 36  ? 105.835 106.504 115.692 1.00 38.40 ? 36  PHE B CE2 1 
ATOM   3379  C CZ  . PHE B 1 36  ? 105.322 106.395 114.435 1.00 38.40 ? 36  PHE B CZ  1 
ATOM   3380  N N   . GLN B 1 37  ? 111.052 109.813 116.790 1.00 41.84 ? 37  GLN B N   1 
ATOM   3381  C CA  . GLN B 1 37  ? 112.359 110.167 117.327 1.00 41.84 ? 37  GLN B CA  1 
ATOM   3382  C C   . GLN B 1 37  ? 113.295 108.971 117.361 1.00 41.84 ? 37  GLN B C   1 
ATOM   3383  O O   . GLN B 1 37  ? 114.511 109.131 117.226 1.00 41.84 ? 37  GLN B O   1 
ATOM   3384  C CB  . GLN B 1 37  ? 112.222 110.731 118.733 1.00 41.84 ? 37  GLN B CB  1 
ATOM   3385  C CG  . GLN B 1 37  ? 111.277 111.879 118.873 1.00 41.84 ? 37  GLN B CG  1 
ATOM   3386  C CD  . GLN B 1 37  ? 111.320 112.456 120.267 1.00 41.84 ? 37  GLN B CD  1 
ATOM   3387  O OE1 . GLN B 1 37  ? 112.236 112.173 121.035 1.00 41.84 ? 37  GLN B OE1 1 
ATOM   3388  N NE2 . GLN B 1 37  ? 110.319 113.250 120.613 1.00 41.84 ? 37  GLN B NE2 1 
ATOM   3389  N N   . HIS B 1 38  ? 112.753 107.774 117.547 1.00 36.84 ? 38  HIS B N   1 
ATOM   3390  C CA  . HIS B 1 38  ? 113.562 106.586 117.731 1.00 36.84 ? 38  HIS B CA  1 
ATOM   3391  C C   . HIS B 1 38  ? 112.887 105.413 117.042 1.00 36.84 ? 38  HIS B C   1 
ATOM   3392  O O   . HIS B 1 38  ? 111.660 105.354 116.944 1.00 36.84 ? 38  HIS B O   1 
ATOM   3393  C CB  . HIS B 1 38  ? 113.764 106.297 119.214 1.00 36.84 ? 38  HIS B CB  1 
ATOM   3394  C CG  . HIS B 1 38  ? 114.846 105.310 119.498 1.00 36.84 ? 38  HIS B CG  1 
ATOM   3395  N ND1 . HIS B 1 38  ? 114.685 103.957 119.308 1.00 36.84 ? 38  HIS B ND1 1 
ATOM   3396  C CD2 . HIS B 1 38  ? 116.099 105.477 119.974 1.00 36.84 ? 38  HIS B CD2 1 
ATOM   3397  C CE1 . HIS B 1 38  ? 115.796 103.331 119.647 1.00 36.84 ? 38  HIS B CE1 1 
ATOM   3398  N NE2 . HIS B 1 38  ? 116.671 104.231 120.055 1.00 36.84 ? 38  HIS B NE2 1 
ATOM   3399  N N   . GLY B 1 39  ? 113.708 104.481 116.555 1.00 38.51 ? 39  GLY B N   1 
ATOM   3400  C CA  . GLY B 1 39  ? 113.168 103.317 115.877 1.00 38.51 ? 39  GLY B CA  1 
ATOM   3401  C C   . GLY B 1 39  ? 112.319 102.453 116.786 1.00 38.51 ? 39  GLY B C   1 
ATOM   3402  O O   . GLY B 1 39  ? 111.296 101.911 116.365 1.00 38.51 ? 39  GLY B O   1 
ATOM   3403  N N   . ASP B 1 40  ? 112.737 102.308 118.045 1.00 38.20 ? 40  ASP B N   1 
ATOM   3404  C CA  . ASP B 1 40  ? 111.954 101.534 118.998 1.00 38.20 ? 40  ASP B CA  1 
ATOM   3405  C C   . ASP B 1 40  ? 110.572 102.123 119.184 1.00 38.20 ? 40  ASP B C   1 
ATOM   3406  O O   . ASP B 1 40  ? 109.610 101.381 119.384 1.00 38.20 ? 40  ASP B O   1 
ATOM   3407  C CB  . ASP B 1 40  ? 112.671 101.453 120.341 1.00 38.20 ? 40  ASP B CB  1 
ATOM   3408  C CG  . ASP B 1 40  ? 113.570 100.242 120.448 1.00 38.20 ? 40  ASP B CG  1 
ATOM   3409  O OD1 . ASP B 1 40  ? 113.735 99.539  119.434 1.00 38.20 ? 40  ASP B OD1 1 
ATOM   3410  O OD2 . ASP B 1 40  ? 114.119 99.992  121.539 1.00 38.20 ? 40  ASP B OD2 1 
ATOM   3411  N N   . HIS B 1 41  ? 110.444 103.447 119.122 1.00 35.54 ? 41  HIS B N   1 
ATOM   3412  C CA  . HIS B 1 41  ? 109.113 104.031 119.156 1.00 35.54 ? 41  HIS B CA  1 
ATOM   3413  C C   . HIS B 1 41  ? 108.309 103.608 117.939 1.00 35.54 ? 41  HIS B C   1 
ATOM   3414  O O   . HIS B 1 41  ? 107.105 103.382 118.042 1.00 35.54 ? 41  HIS B O   1 
ATOM   3415  C CB  . HIS B 1 41  ? 109.180 105.556 119.236 1.00 35.54 ? 41  HIS B CB  1 
ATOM   3416  C CG  . HIS B 1 41  ? 110.119 106.084 120.276 1.00 35.54 ? 41  HIS B CG  1 
ATOM   3417  N ND1 . HIS B 1 41  ? 110.389 107.427 120.409 1.00 35.54 ? 41  HIS B ND1 1 
ATOM   3418  C CD2 . HIS B 1 41  ? 110.851 105.461 121.225 1.00 35.54 ? 41  HIS B CD2 1 
ATOM   3419  C CE1 . HIS B 1 41  ? 111.250 107.608 121.391 1.00 35.54 ? 41  HIS B CE1 1 
ATOM   3420  N NE2 . HIS B 1 41  ? 111.549 106.429 121.902 1.00 35.54 ? 41  HIS B NE2 1 
ATOM   3421  N N   . LYS B 1 42  ? 108.961 103.447 116.789 1.00 38.73 ? 42  LYS B N   1 
ATOM   3422  C CA  . LYS B 1 42  ? 108.246 102.991 115.603 1.00 38.73 ? 42  LYS B CA  1 
ATOM   3423  C C   . LYS B 1 42  ? 107.778 101.552 115.756 1.00 38.73 ? 42  LYS B C   1 
ATOM   3424  O O   . LYS B 1 42  ? 106.648 101.216 115.387 1.00 38.73 ? 42  LYS B O   1 
ATOM   3425  C CB  . LYS B 1 42  ? 109.134 103.131 114.374 1.00 38.73 ? 42  LYS B CB  1 
ATOM   3426  C CG  . LYS B 1 42  ? 108.482 102.655 113.099 1.00 38.73 ? 42  LYS B CG  1 
ATOM   3427  C CD  . LYS B 1 42  ? 107.326 103.546 112.725 1.00 38.73 ? 42  LYS B CD  1 
ATOM   3428  C CE  . LYS B 1 42  ? 106.797 103.243 111.341 1.00 38.73 ? 42  LYS B CE  1 
ATOM   3429  N NZ  . LYS B 1 42  ? 105.908 102.058 111.318 1.00 38.73 ? 42  LYS B NZ  1 
ATOM   3430  N N   . ARG B 1 43  ? 108.631 100.688 116.298 1.00 39.35 ? 43  ARG B N   1 
ATOM   3431  C CA  . ARG B 1 43  ? 108.250 99.294  116.464 1.00 39.35 ? 43  ARG B CA  1 
ATOM   3432  C C   . ARG B 1 43  ? 107.159 99.142  117.515 1.00 39.35 ? 43  ARG B C   1 
ATOM   3433  O O   . ARG B 1 43  ? 106.190 98.396  117.314 1.00 39.35 ? 43  ARG B O   1 
ATOM   3434  C CB  . ARG B 1 43  ? 109.482 98.480  116.816 1.00 39.35 ? 43  ARG B CB  1 
ATOM   3435  C CG  . ARG B 1 43  ? 110.677 98.896  115.998 1.00 39.35 ? 43  ARG B CG  1 
ATOM   3436  C CD  . ARG B 1 43  ? 111.927 98.149  116.378 1.00 39.35 ? 43  ARG B CD  1 
ATOM   3437  N NE  . ARG B 1 43  ? 111.703 96.711  116.392 1.00 39.35 ? 43  ARG B NE  1 
ATOM   3438  C CZ  . ARG B 1 43  ? 111.620 95.954  115.303 1.00 39.35 ? 43  ARG B CZ  1 
ATOM   3439  N NH1 . ARG B 1 43  ? 111.413 94.650  115.418 1.00 39.35 ? 43  ARG B NH1 1 
ATOM   3440  N NH2 . ARG B 1 43  ? 111.746 96.495  114.100 1.00 39.35 ? 43  ARG B NH2 1 
ATOM   3441  N N   . TRP B 1 44  ? 107.288 99.852  118.634 1.00 35.61 ? 44  TRP B N   1 
ATOM   3442  C CA  . TRP B 1 44  ? 106.205 99.896  119.603 1.00 35.61 ? 44  TRP B CA  1 
ATOM   3443  C C   . TRP B 1 44  ? 104.940 100.447 118.981 1.00 35.61 ? 44  TRP B C   1 
ATOM   3444  O O   . TRP B 1 44  ? 103.846 100.032 119.352 1.00 35.61 ? 44  TRP B O   1 
ATOM   3445  C CB  . TRP B 1 44  ? 106.595 100.749 120.803 1.00 35.61 ? 44  TRP B CB  1 
ATOM   3446  C CG  . TRP B 1 44  ? 107.492 100.096 121.794 1.00 35.61 ? 44  TRP B CG  1 
ATOM   3447  C CD1 . TRP B 1 44  ? 108.702 100.539 122.199 1.00 35.61 ? 44  TRP B CD1 1 
ATOM   3448  C CD2 . TRP B 1 44  ? 107.238 98.901  122.527 1.00 35.61 ? 44  TRP B CD2 1 
ATOM   3449  N NE1 . TRP B 1 44  ? 109.232 99.693  123.129 1.00 35.61 ? 44  TRP B NE1 1 
ATOM   3450  C CE2 . TRP B 1 44  ? 108.348 98.675  123.347 1.00 35.61 ? 44  TRP B CE2 1 
ATOM   3451  C CE3 . TRP B 1 44  ? 106.180 97.995  122.566 1.00 35.61 ? 44  TRP B CE3 1 
ATOM   3452  C CZ2 . TRP B 1 44  ? 108.434 97.586  124.190 1.00 35.61 ? 44  TRP B CZ2 1 
ATOM   3453  C CZ3 . TRP B 1 44  ? 106.268 96.919  123.404 1.00 35.61 ? 44  TRP B CZ3 1 
ATOM   3454  C CH2 . TRP B 1 44  ? 107.385 96.721  124.204 1.00 35.61 ? 44  TRP B CH2 1 
ATOM   3455  N N   . TRP B 1 45  ? 105.060 101.396 118.055 1.00 36.32 ? 45  TRP B N   1 
ATOM   3456  C CA  . TRP B 1 45  ? 103.877 101.893 117.369 1.00 36.32 ? 45  TRP B CA  1 
ATOM   3457  C C   . TRP B 1 45  ? 103.218 100.776 116.590 1.00 36.32 ? 45  TRP B C   1 
ATOM   3458  O O   . TRP B 1 45  ? 102.028 100.503 116.760 1.00 36.32 ? 45  TRP B O   1 
ATOM   3459  C CB  . TRP B 1 45  ? 104.248 103.049 116.437 1.00 36.32 ? 45  TRP B CB  1 
ATOM   3460  C CG  . TRP B 1 45  ? 103.073 103.596 115.669 1.00 36.32 ? 45  TRP B CG  1 
ATOM   3461  C CD1 . TRP B 1 45  ? 102.690 103.257 114.410 1.00 36.32 ? 45  TRP B CD1 1 
ATOM   3462  C CD2 . TRP B 1 45  ? 102.130 104.570 116.123 1.00 36.32 ? 45  TRP B CD2 1 
ATOM   3463  N NE1 . TRP B 1 45  ? 101.572 103.955 114.051 1.00 36.32 ? 45  TRP B NE1 1 
ATOM   3464  C CE2 . TRP B 1 45  ? 101.208 104.770 115.088 1.00 36.32 ? 45  TRP B CE2 1 
ATOM   3465  C CE3 . TRP B 1 45  ? 101.976 105.292 117.306 1.00 36.32 ? 45  TRP B CE3 1 
ATOM   3466  C CZ2 . TRP B 1 45  ? 100.150 105.659 115.199 1.00 36.32 ? 45  TRP B CZ2 1 
ATOM   3467  C CZ3 . TRP B 1 45  ? 100.926 106.172 117.411 1.00 36.32 ? 45  TRP B CZ3 1 
ATOM   3468  C CH2 . TRP B 1 45  ? 100.027 106.348 116.367 1.00 36.32 ? 45  TRP B CH2 1 
ATOM   3469  N N   . ASP B 1 46  ? 104.001 100.096 115.757 1.00 37.40 ? 46  ASP B N   1 
ATOM   3470  C CA  . ASP B 1 46  ? 103.482 99.006  114.944 1.00 37.40 ? 46  ASP B CA  1 
ATOM   3471  C C   . ASP B 1 46  ? 102.767 97.969  115.787 1.00 37.40 ? 46  ASP B C   1 
ATOM   3472  O O   . ASP B 1 46  ? 101.752 97.410  115.365 1.00 37.40 ? 46  ASP B O   1 
ATOM   3473  C CB  . ASP B 1 46  ? 104.623 98.362  114.169 1.00 37.40 ? 46  ASP B CB  1 
ATOM   3474  C CG  . ASP B 1 46  ? 105.208 99.285  113.145 1.00 37.40 ? 46  ASP B CG  1 
ATOM   3475  O OD1 . ASP B 1 46  ? 104.483 100.183 112.679 1.00 37.40 ? 46  ASP B OD1 1 
ATOM   3476  O OD2 . ASP B 1 46  ? 106.391 99.116  112.799 1.00 37.40 ? 46  ASP B OD2 1 
ATOM   3477  N N   . VAL B 1 47  ? 103.279 97.698  116.984 1.00 36.89 ? 47  VAL B N   1 
ATOM   3478  C CA  . VAL B 1 47  ? 102.653 96.694  117.843 1.00 36.89 ? 47  VAL B CA  1 
ATOM   3479  C C   . VAL B 1 47  ? 101.417 97.256  118.534 1.00 36.89 ? 47  VAL B C   1 
ATOM   3480  O O   . VAL B 1 47  ? 100.303 96.757  118.356 1.00 36.89 ? 47  VAL B O   1 
ATOM   3481  C CB  . VAL B 1 47  ? 103.665 96.157  118.866 1.00 36.89 ? 47  VAL B CB  1 
ATOM   3482  C CG1 . VAL B 1 47  ? 103.042 95.050  119.682 1.00 36.89 ? 47  VAL B CG1 1 
ATOM   3483  C CG2 . VAL B 1 47  ? 104.888 95.658  118.161 1.00 36.89 ? 47  VAL B CG2 1 
ATOM   3484  N N   . LEU B 1 48  ? 101.596 98.298  119.339 1.00 36.86 ? 48  LEU B N   1 
ATOM   3485  C CA  . LEU B 1 48  ? 100.538 98.775  120.217 1.00 36.86 ? 48  LEU B CA  1 
ATOM   3486  C C   . LEU B 1 48  ? 99.460  99.520  119.456 1.00 36.86 ? 48  LEU B C   1 
ATOM   3487  O O   . LEU B 1 48  ? 98.272  99.250  119.639 1.00 36.86 ? 48  LEU B O   1 
ATOM   3488  C CB  . LEU B 1 48  ? 101.126 99.685  121.290 1.00 36.86 ? 48  LEU B CB  1 
ATOM   3489  C CG  . LEU B 1 48  ? 102.257 99.132  122.142 1.00 36.86 ? 48  LEU B CG  1 
ATOM   3490  C CD1 . LEU B 1 48  ? 102.729 100.192 123.088 1.00 36.86 ? 48  LEU B CD1 1 
ATOM   3491  C CD2 . LEU B 1 48  ? 101.779 97.933  122.902 1.00 36.86 ? 48  LEU B CD2 1 
ATOM   3492  N N   . ALA B 1 49  ? 99.856  100.486 118.631 1.00 38.71 ? 49  ALA B N   1 
ATOM   3493  C CA  . ALA B 1 49  ? 98.900  101.383 117.994 1.00 38.71 ? 49  ALA B CA  1 
ATOM   3494  C C   . ALA B 1 49  ? 97.736  100.673 117.326 1.00 38.71 ? 49  ALA B C   1 
ATOM   3495  O O   . ALA B 1 49  ? 96.619  101.207 117.385 1.00 38.71 ? 49  ALA B O   1 
ATOM   3496  C CB  . ALA B 1 49  ? 99.637  102.270 116.986 1.00 38.71 ? 49  ALA B CB  1 
ATOM   3497  N N   . PRO B 1 50  ? 97.897  99.512  116.691 1.00 38.51 ? 50  PRO B N   1 
ATOM   3498  C CA  . PRO B 1 50  ? 96.704  98.794  116.234 1.00 38.51 ? 50  PRO B CA  1 
ATOM   3499  C C   . PRO B 1 50  ? 95.803  98.370  117.373 1.00 38.51 ? 50  PRO B C   1 
ATOM   3500  O O   . PRO B 1 50  ? 94.596  98.602  117.314 1.00 38.51 ? 50  PRO B O   1 
ATOM   3501  C CB  . PRO B 1 50  ? 97.292  97.599  115.489 1.00 38.51 ? 50  PRO B CB  1 
ATOM   3502  C CG  . PRO B 1 50  ? 98.593  98.068  115.036 1.00 38.51 ? 50  PRO B CG  1 
ATOM   3503  C CD  . PRO B 1 50  ? 99.116  98.923  116.124 1.00 38.51 ? 50  PRO B CD  1 
ATOM   3504  N N   . VAL B 1 51  ? 96.359  97.763  118.420 1.00 41.91 ? 51  VAL B N   1 
ATOM   3505  C CA  . VAL B 1 51  ? 95.545  97.323  119.552 1.00 41.91 ? 51  VAL B CA  1 
ATOM   3506  C C   . VAL B 1 51  ? 94.835  98.509  120.189 1.00 41.91 ? 51  VAL B C   1 
ATOM   3507  O O   . VAL B 1 51  ? 93.629  98.475  120.454 1.00 41.91 ? 51  VAL B O   1 
ATOM   3508  C CB  . VAL B 1 51  ? 96.421  96.586  120.578 1.00 41.91 ? 51  VAL B CB  1 
ATOM   3509  C CG1 . VAL B 1 51  ? 95.617  96.277  121.823 1.00 41.91 ? 51  VAL B CG1 1 
ATOM   3510  C CG2 . VAL B 1 51  ? 97.008  95.322  119.979 1.00 41.91 ? 51  VAL B CG2 1 
ATOM   3511  N N   . PHE B 1 52  ? 95.585  99.573  120.453 1.00 43.39 ? 52  PHE B N   1 
ATOM   3512  C CA  . PHE B 1 52  ? 95.018  100.775 121.048 1.00 43.39 ? 52  PHE B CA  1 
ATOM   3513  C C   . PHE B 1 52  ? 93.932  101.369 120.167 1.00 43.39 ? 52  PHE B C   1 
ATOM   3514  O O   . PHE B 1 52  ? 92.829  101.667 120.634 1.00 43.39 ? 52  PHE B O   1 
ATOM   3515  C CB  . PHE B 1 52  ? 96.128  101.791 121.279 1.00 43.39 ? 52  PHE B CB  1 
ATOM   3516  C CG  . PHE B 1 52  ? 96.927  101.519 122.497 1.00 43.39 ? 52  PHE B CG  1 
ATOM   3517  C CD1 . PHE B 1 52  ? 97.006  100.242 123.002 1.00 43.39 ? 52  PHE B CD1 1 
ATOM   3518  C CD2 . PHE B 1 52  ? 97.572  102.532 123.164 1.00 43.39 ? 52  PHE B CD2 1 
ATOM   3519  C CE1 . PHE B 1 52  ? 97.733  99.972  124.131 1.00 43.39 ? 52  PHE B CE1 1 
ATOM   3520  C CE2 . PHE B 1 52  ? 98.296  102.262 124.294 1.00 43.39 ? 52  PHE B CE2 1 
ATOM   3521  C CZ  . PHE B 1 52  ? 98.378  100.980 124.775 1.00 43.39 ? 52  PHE B CZ  1 
ATOM   3522  N N   . GLY B 1 53  ? 94.242  101.570 118.887 1.00 43.75 ? 53  GLY B N   1 
ATOM   3523  C CA  . GLY B 1 53  ? 93.280  102.142 117.971 1.00 43.75 ? 53  GLY B CA  1 
ATOM   3524  C C   . GLY B 1 53  ? 92.036  101.301 117.818 1.00 43.75 ? 53  GLY B C   1 
ATOM   3525  O O   . GLY B 1 53  ? 90.947  101.838 117.636 1.00 43.75 ? 53  GLY B O   1 
ATOM   3526  N N   . ILE B 1 54  ? 92.167  99.980  117.914 1.00 45.34 ? 54  ILE B N   1 
ATOM   3527  C CA  . ILE B 1 54  ? 90.998  99.128  117.753 1.00 45.34 ? 54  ILE B CA  1 
ATOM   3528  C C   . ILE B 1 54  ? 90.175  99.092  119.030 1.00 45.34 ? 54  ILE B C   1 
ATOM   3529  O O   . ILE B 1 54  ? 88.947  98.994  118.981 1.00 45.34 ? 54  ILE B O   1 
ATOM   3530  C CB  . ILE B 1 54  ? 91.428  97.725  117.311 1.00 45.34 ? 54  ILE B CB  1 
ATOM   3531  C CG1 . ILE B 1 54  ? 91.910  97.763  115.863 1.00 45.34 ? 54  ILE B CG1 1 
ATOM   3532  C CG2 . ILE B 1 54  ? 90.284  96.752  117.444 1.00 45.34 ? 54  ILE B CG2 1 
ATOM   3533  C CD1 . ILE B 1 54  ? 92.894  96.672  115.507 1.00 45.34 ? 54  ILE B CD1 1 
ATOM   3534  N N   . SER B 1 55  ? 90.818  99.183  120.187 1.00 48.37 ? 55  SER B N   1 
ATOM   3535  C CA  . SER B 1 55  ? 90.058  99.325  121.419 1.00 48.37 ? 55  SER B CA  1 
ATOM   3536  C C   . SER B 1 55  ? 89.307  100.645 121.433 1.00 48.37 ? 55  SER B C   1 
ATOM   3537  O O   . SER B 1 55  ? 88.181  100.728 121.932 1.00 48.37 ? 55  SER B O   1 
ATOM   3538  C CB  . SER B 1 55  ? 90.997  99.226  122.615 1.00 48.37 ? 55  SER B CB  1 
ATOM   3539  O OG  . SER B 1 55  ? 91.637  97.964  122.639 1.00 48.37 ? 55  SER B OG  1 
ATOM   3540  N N   . MET B 1 56  ? 89.921  101.688 120.881 1.00 49.10 ? 56  MET B N   1 
ATOM   3541  C CA  . MET B 1 56  ? 89.264  102.982 120.808 1.00 49.10 ? 56  MET B CA  1 
ATOM   3542  C C   . MET B 1 56  ? 88.124  102.972 119.795 1.00 49.10 ? 56  MET B C   1 
ATOM   3543  O O   . MET B 1 56  ? 87.041  103.498 120.064 1.00 49.10 ? 56  MET B O   1 
ATOM   3544  C CB  . MET B 1 56  ? 90.290  104.052 120.460 1.00 49.10 ? 56  MET B CB  1 
ATOM   3545  C CG  . MET B 1 56  ? 91.408  104.190 121.464 1.00 49.10 ? 56  MET B CG  1 
ATOM   3546  S SD  . MET B 1 56  ? 92.397  105.657 121.130 1.00 49.10 ? 56  MET B SD  1 
ATOM   3547  C CE  . MET B 1 56  ? 93.843  105.352 122.123 1.00 49.10 ? 56  MET B CE  1 
ATOM   3548  N N   . ALA B 1 57  ? 88.346  102.376 118.630 1.00 50.30 ? 57  ALA B N   1 
ATOM   3549  C CA  . ALA B 1 57  ? 87.398  102.401 117.531 1.00 50.30 ? 57  ALA B CA  1 
ATOM   3550  C C   . ALA B 1 57  ? 86.401  101.265 117.584 1.00 50.30 ? 57  ALA B C   1 
ATOM   3551  O O   . ALA B 1 57  ? 85.565  101.151 116.686 1.00 50.30 ? 57  ALA B O   1 
ATOM   3552  C CB  . ALA B 1 57  ? 88.146  102.352 116.201 1.00 50.30 ? 57  ALA B CB  1 
ATOM   3553  N N   . SER B 1 58  ? 86.481  100.408 118.591 1.00 54.12 ? 58  SER B N   1 
ATOM   3554  C CA  . SER B 1 58  ? 85.521  99.334  118.772 1.00 54.12 ? 58  SER B CA  1 
ATOM   3555  C C   . SER B 1 58  ? 84.584  99.605  119.937 1.00 54.12 ? 58  SER B C   1 
ATOM   3556  O O   . SER B 1 58  ? 83.786  98.740  120.306 1.00 54.12 ? 58  SER B O   1 
ATOM   3557  C CB  . SER B 1 58  ? 86.263  98.017  118.949 1.00 54.12 ? 58  SER B CB  1 
ATOM   3558  O OG  . SER B 1 58  ? 87.203  98.143  119.991 1.00 54.12 ? 58  SER B OG  1 
ATOM   3559  N N   . ILE B 1 59  ? 84.674  100.796 120.526 1.00 53.30 ? 59  ILE B N   1 
ATOM   3560  C CA  . ILE B 1 59  ? 83.680  101.295 121.462 1.00 53.30 ? 59  ILE B CA  1 
ATOM   3561  C C   . ILE B 1 59  ? 83.112  102.633 121.024 1.00 53.30 ? 59  ILE B C   1 
ATOM   3562  O O   . ILE B 1 59  ? 82.093  103.067 121.560 1.00 53.30 ? 59  ILE B O   1 
ATOM   3563  C CB  . ILE B 1 59  ? 84.271  101.403 122.880 1.00 53.30 ? 59  ILE B CB  1 
ATOM   3564  C CG1 . ILE B 1 59  ? 85.556  102.222 122.839 1.00 53.30 ? 59  ILE B CG1 1 
ATOM   3565  C CG2 . ILE B 1 59  ? 84.556  100.030 123.440 1.00 53.30 ? 59  ILE B CG2 1 
ATOM   3566  C CD1 . ILE B 1 59  ? 86.368  102.146 124.094 1.00 53.30 ? 59  ILE B CD1 1 
ATOM   3567  N N   . GLY B 1 60  ? 83.752  103.303 120.070 1.00 52.85 ? 60  GLY B N   1 
ATOM   3568  C CA  . GLY B 1 60  ? 83.237  104.508 119.472 1.00 52.85 ? 60  GLY B CA  1 
ATOM   3569  C C   . GLY B 1 60  ? 84.033  105.768 119.715 1.00 52.85 ? 60  GLY B C   1 
ATOM   3570  O O   . GLY B 1 60  ? 83.483  106.859 119.528 1.00 52.85 ? 60  GLY B O   1 
ATOM   3571  N N   . TYR B 1 61  ? 85.297  105.672 120.126 1.00 47.12 ? 61  TYR B N   1 
ATOM   3572  C CA  . TYR B 1 61  ? 86.093  106.881 120.301 1.00 47.12 ? 61  TYR B CA  1 
ATOM   3573  C C   . TYR B 1 61  ? 86.137  107.657 118.992 1.00 47.12 ? 61  TYR B C   1 
ATOM   3574  O O   . TYR B 1 61  ? 86.703  107.188 118.003 1.00 47.12 ? 61  TYR B O   1 
ATOM   3575  C CB  . TYR B 1 61  ? 87.511  106.540 120.753 1.00 47.12 ? 61  TYR B CB  1 
ATOM   3576  C CG  . TYR B 1 61  ? 87.670  106.320 122.242 1.00 47.12 ? 61  TYR B CG  1 
ATOM   3577  C CD1 . TYR B 1 61  ? 86.612  105.876 123.015 1.00 47.12 ? 61  TYR B CD1 1 
ATOM   3578  C CD2 . TYR B 1 61  ? 88.889  106.546 122.871 1.00 47.12 ? 61  TYR B CD2 1 
ATOM   3579  C CE1 . TYR B 1 61  ? 86.759  105.669 124.366 1.00 47.12 ? 61  TYR B CE1 1 
ATOM   3580  C CE2 . TYR B 1 61  ? 89.043  106.336 124.220 1.00 47.12 ? 61  TYR B CE2 1 
ATOM   3581  C CZ  . TYR B 1 61  ? 87.973  105.900 124.962 1.00 47.12 ? 61  TYR B CZ  1 
ATOM   3582  O OH  . TYR B 1 61  ? 88.112  105.690 126.311 1.00 47.12 ? 61  TYR B OH  1 
ATOM   3583  N N   . LYS B 1 62  ? 85.514  108.837 118.990 1.00 46.23 ? 62  LYS B N   1 
ATOM   3584  C CA  . LYS B 1 62  ? 85.420  109.658 117.787 1.00 46.23 ? 62  LYS B CA  1 
ATOM   3585  C C   . LYS B 1 62  ? 86.778  109.813 117.124 1.00 46.23 ? 62  LYS B C   1 
ATOM   3586  O O   . LYS B 1 62  ? 87.767  110.143 117.777 1.00 46.23 ? 62  LYS B O   1 
ATOM   3587  C CB  . LYS B 1 62  ? 84.846  111.030 118.133 1.00 46.23 ? 62  LYS B CB  1 
ATOM   3588  C CG  . LYS B 1 62  ? 83.470  110.980 118.762 1.00 46.23 ? 62  LYS B CG  1 
ATOM   3589  C CD  . LYS B 1 62  ? 82.975  112.373 119.112 1.00 46.23 ? 62  LYS B CD  1 
ATOM   3590  C CE  . LYS B 1 62  ? 81.590  112.329 119.738 1.00 46.23 ? 62  LYS B CE  1 
ATOM   3591  N NZ  . LYS B 1 62  ? 81.547  111.526 120.992 1.00 46.23 ? 62  LYS B NZ  1 
ATOM   3592  N N   . LEU B 1 63  ? 86.809  109.587 115.811 1.00 45.41 ? 63  LEU B N   1 
ATOM   3593  C CA  . LEU B 1 63  ? 88.070  109.415 115.101 1.00 45.41 ? 63  LEU B CA  1 
ATOM   3594  C C   . LEU B 1 63  ? 89.038  110.556 115.382 1.00 45.41 ? 63  LEU B C   1 
ATOM   3595  O O   . LEU B 1 63  ? 90.258  110.358 115.360 1.00 45.41 ? 63  LEU B O   1 
ATOM   3596  C CB  . LEU B 1 63  ? 87.791  109.286 113.606 1.00 45.41 ? 63  LEU B CB  1 
ATOM   3597  C CG  . LEU B 1 63  ? 88.829  108.601 112.720 1.00 45.41 ? 63  LEU B CG  1 
ATOM   3598  C CD1 . LEU B 1 63  ? 88.148  108.027 111.496 1.00 45.41 ? 63  LEU B CD1 1 
ATOM   3599  C CD2 . LEU B 1 63  ? 89.918  109.529 112.308 1.00 45.41 ? 63  LEU B CD2 1 
ATOM   3600  N N   . ASP B 1 64  ? 88.515  111.748 115.666 1.00 47.15 ? 64  ASP B N   1 
ATOM   3601  C CA  . ASP B 1 64  ? 89.367  112.848 116.102 1.00 47.15 ? 64  ASP B CA  1 
ATOM   3602  C C   . ASP B 1 64  ? 89.987  112.574 117.463 1.00 47.15 ? 64  ASP B C   1 
ATOM   3603  O O   . ASP B 1 64  ? 91.168  112.863 117.693 1.00 47.15 ? 64  ASP B O   1 
ATOM   3604  C CB  . ASP B 1 64  ? 88.576  114.138 116.165 1.00 47.15 ? 64  ASP B CB  1 
ATOM   3605  C CG  . ASP B 1 64  ? 89.383  115.244 116.750 1.00 47.15 ? 64  ASP B CG  1 
ATOM   3606  O OD1 . ASP B 1 64  ? 90.310  115.701 116.065 1.00 47.15 ? 64  ASP B OD1 1 
ATOM   3607  O OD2 . ASP B 1 64  ? 89.118  115.636 117.903 1.00 47.15 ? 64  ASP B OD2 1 
ATOM   3608  N N   . VAL B 1 65  ? 89.186  112.063 118.400 1.00 44.48 ? 65  VAL B N   1 
ATOM   3609  C CA  . VAL B 1 65  ? 89.726  111.701 119.701 1.00 44.48 ? 65  VAL B CA  1 
ATOM   3610  C C   . VAL B 1 65  ? 90.728  110.573 119.543 1.00 44.48 ? 65  VAL B C   1 
ATOM   3611  O O   . VAL B 1 65  ? 91.715  110.497 120.280 1.00 44.48 ? 65  VAL B O   1 
ATOM   3612  C CB  . VAL B 1 65  ? 88.581  111.338 120.664 1.00 44.48 ? 65  VAL B CB  1 
ATOM   3613  C CG1 . VAL B 1 65  ? 89.119  110.782 121.951 1.00 44.48 ? 65  VAL B CG1 1 
ATOM   3614  C CG2 . VAL B 1 65  ? 87.726  112.555 120.941 1.00 44.48 ? 65  VAL B CG2 1 
ATOM   3615  N N   . GLN B 1 66  ? 90.504  109.690 118.573 1.00 42.01 ? 66  GLN B N   1 
ATOM   3616  C CA  . GLN B 1 66  ? 91.508  108.687 118.254 1.00 42.01 ? 66  GLN B CA  1 
ATOM   3617  C C   . GLN B 1 66  ? 92.811  109.348 117.846 1.00 42.01 ? 66  GLN B C   1 
ATOM   3618  O O   . GLN B 1 66  ? 93.883  108.986 118.332 1.00 42.01 ? 66  GLN B O   1 
ATOM   3619  C CB  . GLN B 1 66  ? 91.012  107.777 117.139 1.00 42.01 ? 66  GLN B CB  1 
ATOM   3620  C CG  . GLN B 1 66  ? 89.863  106.892 117.497 1.00 42.01 ? 66  GLN B CG  1 
ATOM   3621  C CD  . GLN B 1 66  ? 89.489  105.988 116.356 1.00 42.01 ? 66  GLN B CD  1 
ATOM   3622  O OE1 . GLN B 1 66  ? 90.312  105.676 115.509 1.00 42.01 ? 66  GLN B OE1 1 
ATOM   3623  N NE2 . GLN B 1 66  ? 88.245  105.570 116.319 1.00 42.01 ? 66  GLN B NE2 1 
ATOM   3624  N N   . TYR B 1 67  ? 92.737  110.306 116.925 1.00 43.76 ? 67  TYR B N   1 
ATOM   3625  C CA  . TYR B 1 67  ? 93.923  111.069 116.555 1.00 43.76 ? 67  TYR B CA  1 
ATOM   3626  C C   . TYR B 1 67  ? 94.612  111.646 117.781 1.00 43.76 ? 67  TYR B C   1 
ATOM   3627  O O   . TYR B 1 67  ? 95.830  111.516 117.937 1.00 43.76 ? 67  TYR B O   1 
ATOM   3628  C CB  . TYR B 1 67  ? 93.530  112.178 115.590 1.00 43.76 ? 67  TYR B CB  1 
ATOM   3629  C CG  . TYR B 1 67  ? 93.534  111.751 114.150 1.00 43.76 ? 67  TYR B CG  1 
ATOM   3630  C CD1 . TYR B 1 67  ? 94.578  111.013 113.632 1.00 43.76 ? 67  TYR B CD1 1 
ATOM   3631  C CD2 . TYR B 1 67  ? 92.469  112.040 113.323 1.00 43.76 ? 67  TYR B CD2 1 
ATOM   3632  C CE1 . TYR B 1 67  ? 94.578  110.613 112.317 1.00 43.76 ? 67  TYR B CE1 1 
ATOM   3633  C CE2 . TYR B 1 67  ? 92.464  111.644 112.015 1.00 43.76 ? 67  TYR B CE2 1 
ATOM   3634  C CZ  . TYR B 1 67  ? 93.515  110.921 111.519 1.00 43.76 ? 67  TYR B CZ  1 
ATOM   3635  O OH  . TYR B 1 67  ? 93.517  110.511 110.211 1.00 43.76 ? 67  TYR B OH  1 
ATOM   3636  N N   . ARG B 1 68  ? 93.839  112.258 118.678 1.00 44.31 ? 68  ARG B N   1 
ATOM   3637  C CA  . ARG B 1 68  ? 94.421  112.934 119.833 1.00 44.31 ? 68  ARG B CA  1 
ATOM   3638  C C   . ARG B 1 68  ? 95.117  111.952 120.762 1.00 44.31 ? 68  ARG B C   1 
ATOM   3639  O O   . ARG B 1 68  ? 96.275  112.153 121.143 1.00 44.31 ? 68  ARG B O   1 
ATOM   3640  C CB  . ARG B 1 68  ? 93.343  113.703 120.588 1.00 44.31 ? 68  ARG B CB  1 
ATOM   3641  C CG  . ARG B 1 68  ? 92.775  114.859 119.807 1.00 44.31 ? 68  ARG B CG  1 
ATOM   3642  C CD  . ARG B 1 68  ? 92.029  115.811 120.705 1.00 44.31 ? 68  ARG B CD  1 
ATOM   3643  N NE  . ARG B 1 68  ? 92.895  116.336 121.747 1.00 44.31 ? 68  ARG B NE  1 
ATOM   3644  C CZ  . ARG B 1 68  ? 92.512  117.231 122.646 1.00 44.31 ? 68  ARG B CZ  1 
ATOM   3645  N NH1 . ARG B 1 68  ? 91.273  117.698 122.626 1.00 44.31 ? 68  ARG B NH1 1 
ATOM   3646  N NH2 . ARG B 1 68  ? 93.366  117.657 123.565 1.00 44.31 ? 68  ARG B NH2 1 
ATOM   3647  N N   . HIS B 1 69  ? 94.420  110.887 121.153 1.00 40.59 ? 69  HIS B N   1 
ATOM   3648  C CA  . HIS B 1 69  ? 95.011  109.930 122.081 1.00 40.59 ? 69  HIS B CA  1 
ATOM   3649  C C   . HIS B 1 69  ? 96.186  109.210 121.447 1.00 40.59 ? 69  HIS B C   1 
ATOM   3650  O O   . HIS B 1 69  ? 97.171  108.915 122.122 1.00 40.59 ? 69  HIS B O   1 
ATOM   3651  C CB  . HIS B 1 69  ? 93.965  108.927 122.552 1.00 40.59 ? 69  HIS B CB  1 
ATOM   3652  C CG  . HIS B 1 69  ? 93.054  109.454 123.615 1.00 40.59 ? 69  HIS B CG  1 
ATOM   3653  N ND1 . HIS B 1 69  ? 93.494  110.257 124.642 1.00 40.59 ? 69  HIS B ND1 1 
ATOM   3654  C CD2 . HIS B 1 69  ? 91.728  109.284 123.814 1.00 40.59 ? 69  HIS B CD2 1 
ATOM   3655  C CE1 . HIS B 1 69  ? 92.476  110.561 125.425 1.00 40.59 ? 69  HIS B CE1 1 
ATOM   3656  N NE2 . HIS B 1 69  ? 91.393  109.984 124.944 1.00 40.59 ? 69  HIS B NE2 1 
ATOM   3657  N N   . LEU B 1 70  ? 96.105  108.919 120.152 1.00 39.15 ? 70  LEU B N   1 
ATOM   3658  C CA  . LEU B 1 70  ? 97.214  108.267 119.481 1.00 39.15 ? 70  LEU B CA  1 
ATOM   3659  C C   . LEU B 1 70  ? 98.408  109.192 119.375 1.00 39.15 ? 70  LEU B C   1 
ATOM   3660  O O   . LEU B 1 70  ? 99.548  108.733 119.416 1.00 39.15 ? 70  LEU B O   1 
ATOM   3661  C CB  . LEU B 1 70  ? 96.772  107.786 118.106 1.00 39.15 ? 70  LEU B CB  1 
ATOM   3662  C CG  . LEU B 1 70  ? 95.862  106.564 118.170 1.00 39.15 ? 70  LEU B CG  1 
ATOM   3663  C CD1 . LEU B 1 70  ? 95.117  106.353 116.872 1.00 39.15 ? 70  LEU B CD1 1 
ATOM   3664  C CD2 . LEU B 1 70  ? 96.671  105.350 118.522 1.00 39.15 ? 70  LEU B CD2 1 
ATOM   3665  N N   . LEU B 1 71  ? 98.175  110.496 119.284 1.00 37.86 ? 71  LEU B N   1 
ATOM   3666  C CA  . LEU B 1 71  ? 99.289  111.430 119.292 1.00 37.86 ? 71  LEU B CA  1 
ATOM   3667  C C   . LEU B 1 71  ? 99.864  111.611 120.686 1.00 37.86 ? 71  LEU B C   1 
ATOM   3668  O O   . LEU B 1 71  ? 101.052 111.904 120.824 1.00 37.86 ? 71  LEU B O   1 
ATOM   3669  C CB  . LEU B 1 71  ? 98.841  112.766 118.714 1.00 37.86 ? 71  LEU B CB  1 
ATOM   3670  C CG  . LEU B 1 71  ? 98.622  112.710 117.208 1.00 37.86 ? 71  LEU B CG  1 
ATOM   3671  C CD1 . LEU B 1 71  ? 97.858  113.917 116.761 1.00 37.86 ? 71  LEU B CD1 1 
ATOM   3672  C CD2 . LEU B 1 71  ? 99.943  112.621 116.485 1.00 37.86 ? 71  LEU B CD2 1 
ATOM   3673  N N   . VAL B 1 72  ? 99.044  111.432 121.720 1.00 38.08 ? 72  VAL B N   1 
ATOM   3674  C CA  . VAL B 1 72  ? 99.559  111.412 123.088 1.00 38.08 ? 72  VAL B CA  1 
ATOM   3675  C C   . VAL B 1 72  ? 100.409 110.170 123.312 1.00 38.08 ? 72  VAL B C   1 
ATOM   3676  O O   . VAL B 1 72  ? 101.514 110.239 123.857 1.00 38.08 ? 72  VAL B O   1 
ATOM   3677  C CB  . VAL B 1 72  ? 98.403  111.488 124.101 1.00 38.08 ? 72  VAL B CB  1 
ATOM   3678  C CG1 . VAL B 1 72  ? 98.907  111.192 125.475 1.00 38.08 ? 72  VAL B CG1 1 
ATOM   3679  C CG2 . VAL B 1 72  ? 97.770  112.860 124.090 1.00 38.08 ? 72  VAL B CG2 1 
ATOM   3680  N N   . LEU B 1 73  ? 99.895  109.017 122.901 1.00 34.73 ? 73  LEU B N   1 
ATOM   3681  C CA  . LEU B 1 73  ? 100.653 107.774 122.938 1.00 34.73 ? 73  LEU B CA  1 
ATOM   3682  C C   . LEU B 1 73  ? 101.944 107.885 122.144 1.00 34.73 ? 73  LEU B C   1 
ATOM   3683  O O   . LEU B 1 73  ? 102.976 107.347 122.544 1.00 34.73 ? 73  LEU B O   1 
ATOM   3684  C CB  . LEU B 1 73  ? 99.774  106.646 122.401 1.00 34.73 ? 73  LEU B CB  1 
ATOM   3685  C CG  . LEU B 1 73  ? 100.360 105.369 121.813 1.00 34.73 ? 73  LEU B CG  1 
ATOM   3686  C CD1 . LEU B 1 73  ? 100.806 104.424 122.887 1.00 34.73 ? 73  LEU B CD1 1 
ATOM   3687  C CD2 . LEU B 1 73  ? 99.332  104.701 120.942 1.00 34.73 ? 73  LEU B CD2 1 
ATOM   3688  N N   . TYR B 1 74  ? 101.900 108.577 121.011 1.00 35.83 ? 74  TYR B N   1 
ATOM   3689  C CA  . TYR B 1 74  ? 103.092 108.806 120.211 1.00 35.83 ? 74  TYR B CA  1 
ATOM   3690  C C   . TYR B 1 74  ? 104.033 109.791 120.880 1.00 35.83 ? 74  TYR B C   1 
ATOM   3691  O O   . TYR B 1 74  ? 105.248 109.728 120.672 1.00 35.83 ? 74  TYR B O   1 
ATOM   3692  C CB  . TYR B 1 74  ? 102.670 109.306 118.833 1.00 35.83 ? 74  TYR B CB  1 
ATOM   3693  C CG  . TYR B 1 74  ? 103.646 110.226 118.141 1.00 35.83 ? 74  TYR B CG  1 
ATOM   3694  C CD1 . TYR B 1 74  ? 104.776 109.730 117.522 1.00 35.83 ? 74  TYR B CD1 1 
ATOM   3695  C CD2 . TYR B 1 74  ? 103.416 111.587 118.074 1.00 35.83 ? 74  TYR B CD2 1 
ATOM   3696  C CE1 . TYR B 1 74  ? 105.655 110.560 116.877 1.00 35.83 ? 74  TYR B CE1 1 
ATOM   3697  C CE2 . TYR B 1 74  ? 104.293 112.422 117.432 1.00 35.83 ? 74  TYR B CE2 1 
ATOM   3698  C CZ  . TYR B 1 74  ? 105.411 111.900 116.838 1.00 35.83 ? 74  TYR B CZ  1 
ATOM   3699  O OH  . TYR B 1 74  ? 106.293 112.721 116.191 1.00 35.83 ? 74  TYR B OH  1 
ATOM   3700  N N   . ASP B 1 75  ? 103.496 110.686 121.702 1.00 39.90 ? 75  ASP B N   1 
ATOM   3701  C CA  . ASP B 1 75  ? 104.241 111.800 122.263 1.00 39.90 ? 75  ASP B CA  1 
ATOM   3702  C C   . ASP B 1 75  ? 104.665 111.582 123.704 1.00 39.90 ? 75  ASP B C   1 
ATOM   3703  O O   . ASP B 1 75  ? 105.801 111.899 124.064 1.00 39.90 ? 75  ASP B O   1 
ATOM   3704  C CB  . ASP B 1 75  ? 103.397 113.067 122.179 1.00 39.90 ? 75  ASP B CB  1 
ATOM   3705  C CG  . ASP B 1 75  ? 104.149 114.290 122.622 1.00 39.90 ? 75  ASP B CG  1 
ATOM   3706  O OD1 . ASP B 1 75  ? 105.275 114.505 122.131 1.00 39.90 ? 75  ASP B OD1 1 
ATOM   3707  O OD2 . ASP B 1 75  ? 103.617 115.039 123.463 1.00 39.90 ? 75  ASP B OD2 1 
ATOM   3708  N N   . ALA B 1 76  ? 103.784 111.047 124.541 1.00 36.99 ? 76  ALA B N   1 
ATOM   3709  C CA  . ALA B 1 76  ? 104.037 110.984 125.971 1.00 36.99 ? 76  ALA B CA  1 
ATOM   3710  C C   . ALA B 1 76  ? 104.490 109.611 126.450 1.00 36.99 ? 76  ALA B C   1 
ATOM   3711  O O   . ALA B 1 76  ? 105.473 109.515 127.186 1.00 36.99 ? 76  ALA B O   1 
ATOM   3712  C CB  . ALA B 1 76  ? 102.784 111.416 126.736 1.00 36.99 ? 76  ALA B CB  1 
ATOM   3713  N N   . VAL B 1 77  ? 103.806 108.541 126.060 1.00 34.40 ? 77  VAL B N   1 
ATOM   3714  C CA  . VAL B 1 77  ? 103.980 107.259 126.721 1.00 34.40 ? 77  VAL B CA  1 
ATOM   3715  C C   . VAL B 1 77  ? 104.970 106.360 125.988 1.00 34.40 ? 77  VAL B C   1 
ATOM   3716  O O   . VAL B 1 77  ? 105.748 105.658 126.630 1.00 34.40 ? 77  VAL B O   1 
ATOM   3717  C CB  . VAL B 1 77  ? 102.619 106.560 126.922 1.00 34.40 ? 77  VAL B CB  1 
ATOM   3718  C CG1 . VAL B 1 77  ? 101.595 107.548 127.420 1.00 34.40 ? 77  VAL B CG1 1 
ATOM   3719  C CG2 . VAL B 1 77  ? 102.153 105.913 125.682 1.00 34.40 ? 77  VAL B CG2 1 
ATOM   3720  N N   . ILE B 1 78  ? 104.982 106.352 124.660 1.00 32.13 ? 78  ILE B N   1 
ATOM   3721  C CA  . ILE B 1 78  ? 105.903 105.469 123.947 1.00 32.13 ? 78  ILE B CA  1 
ATOM   3722  C C   . ILE B 1 78  ? 107.344 105.923 124.137 1.00 32.13 ? 78  ILE B C   1 
ATOM   3723  O O   . ILE B 1 78  ? 108.224 105.070 124.295 1.00 32.13 ? 78  ILE B O   1 
ATOM   3724  C CB  . ILE B 1 78  ? 105.561 105.344 122.455 1.00 32.13 ? 78  ILE B CB  1 
ATOM   3725  C CG1 . ILE B 1 78  ? 104.341 104.457 122.251 1.00 32.13 ? 78  ILE B CG1 1 
ATOM   3726  C CG2 . ILE B 1 78  ? 106.706 104.758 121.707 1.00 32.13 ? 78  ILE B CG2 1 
ATOM   3727  C CD1 . ILE B 1 78  ? 103.877 104.393 120.834 1.00 32.13 ? 78  ILE B CD1 1 
ATOM   3728  N N   . PRO B 1 79  ? 107.654 107.212 124.145 1.00 32.09 ? 79  PRO B N   1 
ATOM   3729  C CA  . PRO B 1 79  ? 109.031 107.597 124.468 1.00 32.09 ? 79  PRO B CA  1 
ATOM   3730  C C   . PRO B 1 79  ? 109.411 107.254 125.897 1.00 32.09 ? 79  PRO B C   1 
ATOM   3731  O O   . PRO B 1 79  ? 110.581 107.338 126.275 1.00 32.09 ? 79  PRO B O   1 
ATOM   3732  C CB  . PRO B 1 79  ? 109.033 109.106 124.230 1.00 32.09 ? 79  PRO B CB  1 
ATOM   3733  C CG  . PRO B 1 79  ? 107.965 109.319 123.269 1.00 32.09 ? 79  PRO B CG  1 
ATOM   3734  C CD  . PRO B 1 79  ? 106.903 108.356 123.608 1.00 32.09 ? 79  PRO B CD  1 
ATOM   3735  N N   . ASN B 1 80  ? 108.423 106.851 126.694 1.00 36.49 ? 80  ASN B N   1 
ATOM   3736  C CA  . ASN B 1 80  ? 108.611 106.482 128.091 1.00 36.49 ? 80  ASN B CA  1 
ATOM   3737  C C   . ASN B 1 80  ? 108.193 105.039 128.331 1.00 36.49 ? 80  ASN B C   1 
ATOM   3738  O O   . ASN B 1 80  ? 107.581 104.723 129.350 1.00 36.49 ? 80  ASN B O   1 
ATOM   3739  C CB  . ASN B 1 80  ? 107.831 107.419 129.010 1.00 36.49 ? 80  ASN B CB  1 
ATOM   3740  C CG  . ASN B 1 80  ? 108.308 108.847 128.919 1.00 36.49 ? 80  ASN B CG  1 
ATOM   3741  O OD1 . ASN B 1 80  ? 109.442 109.155 129.273 1.00 36.49 ? 80  ASN B OD1 1 
ATOM   3742  N ND2 . ASN B 1 80  ? 107.445 109.730 128.440 1.00 36.49 ? 80  ASN B ND2 1 
ATOM   3743  N N   . MET B 1 81  ? 108.494 104.160 127.383 1.00 36.49 ? 81  MET B N   1 
ATOM   3744  C CA  . MET B 1 81  ? 108.158 102.753 127.490 1.00 36.49 ? 81  MET B CA  1 
ATOM   3745  C C   . MET B 1 81  ? 109.382 101.865 127.587 1.00 36.49 ? 81  MET B C   1 
ATOM   3746  O O   . MET B 1 81  ? 109.260 100.708 127.999 1.00 36.49 ? 81  MET B O   1 
ATOM   3747  C CB  . MET B 1 81  ? 107.315 102.324 126.288 1.00 36.49 ? 81  MET B CB  1 
ATOM   3748  C CG  . MET B 1 81  ? 106.602 101.020 126.470 1.00 36.49 ? 81  MET B CG  1 
ATOM   3749  S SD  . MET B 1 81  ? 105.167 100.893 125.423 1.00 36.49 ? 81  MET B SD  1 
ATOM   3750  C CE  . MET B 1 81  ? 104.341 102.412 125.832 1.00 36.49 ? 81  MET B CE  1 
ATOM   3751  N N   . GLY B 1 82  ? 110.552 102.376 127.245 1.00 37.14 ? 82  GLY B N   1 
ATOM   3752  C CA  . GLY B 1 82  ? 111.750 101.585 127.283 1.00 37.14 ? 82  GLY B CA  1 
ATOM   3753  C C   . GLY B 1 82  ? 111.924 100.850 125.981 1.00 37.14 ? 82  GLY B C   1 
ATOM   3754  O O   . GLY B 1 82  ? 111.075 100.916 125.091 1.00 37.14 ? 82  GLY B O   1 
ATOM   3755  N N   . PRO B 1 83  ? 113.024 100.123 125.846 1.00 40.37 ? 83  PRO B N   1 
ATOM   3756  C CA  . PRO B 1 83  ? 113.346 99.518  124.555 1.00 40.37 ? 83  PRO B CA  1 
ATOM   3757  C C   . PRO B 1 83  ? 112.360 98.427  124.180 1.00 40.37 ? 83  PRO B C   1 
ATOM   3758  O O   . PRO B 1 83  ? 111.575 97.957  125.004 1.00 40.37 ? 83  PRO B O   1 
ATOM   3759  C CB  . PRO B 1 83  ? 114.750 98.957  124.772 1.00 40.37 ? 83  PRO B CB  1 
ATOM   3760  C CG  . PRO B 1 83  ? 114.830 98.729  126.217 1.00 40.37 ? 83  PRO B CG  1 
ATOM   3761  C CD  . PRO B 1 83  ? 114.026 99.803  126.868 1.00 40.37 ? 83  PRO B CD  1 
ATOM   3762  N N   . PHE B 1 84  ? 112.379 98.017  122.890 1.00 39.96 ? 84  PHE B N   1 
ATOM   3763  C CA  . PHE B 1 84  ? 111.407 97.023  122.311 1.00 39.96 ? 84  PHE B CA  1 
ATOM   3764  C C   . PHE B 1 84  ? 111.927 95.632  122.408 1.00 39.96 ? 84  PHE B C   1 
ATOM   3765  O O   . PHE B 1 84  ? 113.098 95.388  122.199 1.00 39.96 ? 84  PHE B O   1 
ATOM   3766  C CB  . PHE B 1 84  ? 111.116 97.361  120.836 1.00 39.96 ? 84  PHE B CB  1 
ATOM   3767  C CG  . PHE B 1 84  ? 110.111 96.479  120.181 1.00 39.96 ? 84  PHE B CG  1 
ATOM   3768  C CD1 . PHE B 1 84  ? 108.784 96.640  120.428 1.00 39.96 ? 84  PHE B CD1 1 
ATOM   3769  C CD2 . PHE B 1 84  ? 110.501 95.513  119.291 1.00 39.96 ? 84  PHE B CD2 1 
ATOM   3770  C CE1 . PHE B 1 84  ? 107.856 95.835  119.840 1.00 39.96 ? 84  PHE B CE1 1 
ATOM   3771  C CE2 . PHE B 1 84  ? 109.574 94.700  118.691 1.00 39.96 ? 84  PHE B CE2 1 
ATOM   3772  C CZ  . PHE B 1 84  ? 108.248 94.863  118.968 1.00 39.96 ? 84  PHE B CZ  1 
ATOM   3773  N N   . PRO B 1 85  ? 111.048 94.690  122.719 1.00 41.57 ? 85  PRO B N   1 
ATOM   3774  C CA  . PRO B 1 85  ? 111.681 93.425  122.909 1.00 41.57 ? 85  PRO B CA  1 
ATOM   3775  C C   . PRO B 1 85  ? 112.218 92.862  121.633 1.00 41.57 ? 85  PRO B C   1 
ATOM   3776  O O   . PRO B 1 85  ? 111.491 92.656  120.687 1.00 41.57 ? 85  PRO B O   1 
ATOM   3777  C CB  . PRO B 1 85  ? 110.556 92.582  123.438 1.00 41.57 ? 85  PRO B CB  1 
ATOM   3778  C CG  . PRO B 1 85  ? 109.308 93.278  123.096 1.00 41.57 ? 85  PRO B CG  1 
ATOM   3779  C CD  . PRO B 1 85  ? 109.682 94.691  123.223 1.00 41.57 ? 85  PRO B CD  1 
ATOM   3780  N N   . ASN B 1 86  ? 113.483 92.542  121.602 1.00 51.38 ? 86  ASN B N   1 
ATOM   3781  C CA  . ASN B 1 86  ? 114.020 91.887  120.444 1.00 51.38 ? 86  ASN B CA  1 
ATOM   3782  C C   . ASN B 1 86  ? 113.769 90.386  120.559 1.00 51.38 ? 86  ASN B C   1 
ATOM   3783  O O   . ASN B 1 86  ? 113.103 89.951  121.476 1.00 51.38 ? 86  ASN B O   1 
ATOM   3784  C CB  . ASN B 1 86  ? 115.475 92.298  120.096 1.00 51.38 ? 86  ASN B CB  1 
ATOM   3785  C CG  . ASN B 1 86  ? 116.528 91.717  121.020 1.00 51.38 ? 86  ASN B CG  1 
ATOM   3786  O OD1 . ASN B 1 86  ? 116.369 90.657  121.604 1.00 51.38 ? 86  ASN B OD1 1 
ATOM   3787  N ND2 . ASN B 1 86  ? 117.649 92.408  121.108 1.00 51.38 ? 86  ASN B ND2 1 
ATOM   3788  N N   . SER B 1 87  ? 114.290 89.580  119.651 1.00 56.31 ? 87  SER B N   1 
ATOM   3789  C CA  . SER B 1 87  ? 113.997 88.148  119.621 1.00 56.31 ? 87  SER B CA  1 
ATOM   3790  C C   . SER B 1 87  ? 114.364 87.335  120.833 1.00 56.31 ? 87  SER B C   1 
ATOM   3791  O O   . SER B 1 87  ? 113.625 86.450  121.242 1.00 56.31 ? 87  SER B O   1 
ATOM   3792  C CB  . SER B 1 87  ? 114.763 87.564  118.464 1.00 56.31 ? 87  SER B CB  1 
ATOM   3793  O OG  . SER B 1 87  ? 116.150 87.801  118.615 1.00 56.31 ? 87  SER B OG  1 
ATOM   3794  N N   . ASN B 1 88  ? 115.513 87.603  121.408 1.00 56.68 ? 88  ASN B N   1 
ATOM   3795  C CA  . ASN B 1 88  ? 115.866 86.919  122.610 1.00 56.68 ? 88  ASN B CA  1 
ATOM   3796  C C   . ASN B 1 88  ? 115.761 87.900  123.747 1.00 56.68 ? 88  ASN B C   1 
ATOM   3797  O O   . ASN B 1 88  ? 116.395 87.683  124.769 1.00 56.68 ? 88  ASN B O   1 
ATOM   3798  C CB  . ASN B 1 88  ? 117.282 86.384  122.509 1.00 56.68 ? 88  ASN B CB  1 
ATOM   3799  C CG  . ASN B 1 88  ? 118.266 87.377  121.938 1.00 56.68 ? 88  ASN B CG  1 
ATOM   3800  O OD1 . ASN B 1 88  ? 117.998 88.055  120.953 1.00 56.68 ? 88  ASN B OD1 1 
ATOM   3801  N ND2 . ASN B 1 88  ? 119.447 87.423  122.529 1.00 56.68 ? 88  ASN B ND2 1 
ATOM   3802  N N   . ALA B 1 89  ? 114.943 88.950  123.618 1.00 53.57 ? 89  ALA B N   1 
ATOM   3803  C CA  . ALA B 1 89  ? 114.902 90.000  124.631 1.00 53.57 ? 89  ALA B CA  1 
ATOM   3804  C C   . ALA B 1 89  ? 116.289 90.248  125.208 1.00 53.57 ? 89  ALA B C   1 
ATOM   3805  O O   . ALA B 1 89  ? 116.460 90.337  126.426 1.00 53.57 ? 89  ALA B O   1 
ATOM   3806  C CB  . ALA B 1 89  ? 113.910 89.650  125.741 1.00 53.57 ? 89  ALA B CB  1 
ATOM   3807  N N   . SER B 1 90  ? 117.288 90.353  124.333 1.00 53.99 ? 90  SER B N   1 
ATOM   3808  C CA  . SER B 1 90  ? 118.639 90.666  124.779 1.00 53.99 ? 90  SER B CA  1 
ATOM   3809  C C   . SER B 1 90  ? 118.758 92.105  125.256 1.00 53.99 ? 90  SER B C   1 
ATOM   3810  O O   . SER B 1 90  ? 119.545 92.393  126.161 1.00 53.99 ? 90  SER B O   1 
ATOM   3811  C CB  . SER B 1 90  ? 119.626 90.407  123.646 1.00 53.99 ? 90  SER B CB  1 
ATOM   3812  O OG  . SER B 1 90  ? 120.926 90.835  123.995 1.00 53.99 ? 90  SER B OG  1 
ATOM   3813  N N   . ASN B 1 91  ? 117.991 93.015  124.661 1.00 50.03 ? 91  ASN B N   1 
ATOM   3814  C CA  . ASN B 1 91  ? 118.124 94.436  124.945 1.00 50.03 ? 91  ASN B CA  1 
ATOM   3815  C C   . ASN B 1 91  ? 117.422 94.858  126.225 1.00 50.03 ? 91  ASN B C   1 
ATOM   3816  O O   . ASN B 1 91  ? 117.722 95.932  126.748 1.00 50.03 ? 91  ASN B O   1 
ATOM   3817  C CB  . ASN B 1 91  ? 117.570 95.247  123.779 1.00 50.03 ? 91  ASN B CB  1 
ATOM   3818  C CG  . ASN B 1 91  ? 116.128 94.918  123.485 1.00 50.03 ? 91  ASN B CG  1 
ATOM   3819  O OD1 . ASN B 1 91  ? 115.569 93.983  124.052 1.00 50.03 ? 91  ASN B OD1 1 
ATOM   3820  N ND2 . ASN B 1 91  ? 115.514 95.683  122.595 1.00 50.03 ? 91  ASN B ND2 1 
ATOM   3821  N N   . ILE B 1 92  ? 116.494 94.054  126.733 1.00 47.02 ? 92  ILE B N   1 
ATOM   3822  C CA  . ILE B 1 92  ? 115.766 94.400  127.948 1.00 47.02 ? 92  ILE B CA  1 
ATOM   3823  C C   . ILE B 1 92  ? 116.725 94.308  129.131 1.00 47.02 ? 92  ILE B C   1 
ATOM   3824  O O   . ILE B 1 92  ? 117.104 93.211  129.547 1.00 47.02 ? 92  ILE B O   1 
ATOM   3825  C CB  . ILE B 1 92  ? 114.556 93.487  128.147 1.00 47.02 ? 92  ILE B CB  1 
ATOM   3826  C CG1 . ILE B 1 92  ? 113.614 93.595  126.951 1.00 47.02 ? 92  ILE B CG1 1 
ATOM   3827  C CG2 . ILE B 1 92  ? 113.851 93.823  129.429 1.00 47.02 ? 92  ILE B CG2 1 
ATOM   3828  C CD1 . ILE B 1 92  ? 113.056 94.970  126.724 1.00 47.02 ? 92  ILE B CD1 1 
ATOM   3829  N N   . THR B 1 93  ? 117.113 95.455  129.684 1.00 44.28 ? 93  THR B N   1 
ATOM   3830  C CA  . THR B 1 93  ? 118.024 95.490  130.816 1.00 44.28 ? 93  THR B CA  1 
ATOM   3831  C C   . THR B 1 93  ? 117.348 95.837  132.130 1.00 44.28 ? 93  THR B C   1 
ATOM   3832  O O   . THR B 1 93  ? 117.990 95.739  133.178 1.00 44.28 ? 93  THR B O   1 
ATOM   3833  C CB  . THR B 1 93  ? 119.152 96.495  130.569 1.00 44.28 ? 93  THR B CB  1 
ATOM   3834  O OG1 . THR B 1 93  ? 118.636 97.819  130.689 1.00 44.28 ? 93  THR B OG1 1 
ATOM   3835  C CG2 . THR B 1 93  ? 119.723 96.318  129.188 1.00 44.28 ? 93  THR B CG2 1 
ATOM   3836  N N   . TRP B 1 94  ? 116.086 96.241  132.108 1.00 41.98 ? 94  TRP B N   1 
ATOM   3837  C CA  . TRP B 1 94  ? 115.341 96.575  133.317 1.00 41.98 ? 94  TRP B CA  1 
ATOM   3838  C C   . TRP B 1 94  ? 114.483 95.364  133.659 1.00 41.98 ? 94  TRP B C   1 
ATOM   3839  O O   . TRP B 1 94  ? 113.374 95.205  133.154 1.00 41.98 ? 94  TRP B O   1 
ATOM   3840  C CB  . TRP B 1 94  ? 114.511 97.828  133.097 1.00 41.98 ? 94  TRP B CB  1 
ATOM   3841  C CG  . TRP B 1 94  ? 113.598 98.177  134.214 1.00 41.98 ? 94  TRP B CG  1 
ATOM   3842  C CD1 . TRP B 1 94  ? 112.255 98.005  134.248 1.00 41.98 ? 94  TRP B CD1 1 
ATOM   3843  C CD2 . TRP B 1 94  ? 113.957 98.785  135.454 1.00 41.98 ? 94  TRP B CD2 1 
ATOM   3844  N NE1 . TRP B 1 94  ? 111.751 98.457  135.437 1.00 41.98 ? 94  TRP B NE1 1 
ATOM   3845  C CE2 . TRP B 1 94  ? 112.781 98.941  136.197 1.00 41.98 ? 94  TRP B CE2 1 
ATOM   3846  C CE3 . TRP B 1 94  ? 115.162 99.208  136.010 1.00 41.98 ? 94  TRP B CE3 1 
ATOM   3847  C CZ2 . TRP B 1 94  ? 112.773 99.499  137.464 1.00 41.98 ? 94  TRP B CZ2 1 
ATOM   3848  C CZ3 . TRP B 1 94  ? 115.151 99.759  137.264 1.00 41.98 ? 94  TRP B CZ3 1 
ATOM   3849  C CH2 . TRP B 1 94  ? 113.967 99.901  137.979 1.00 41.98 ? 94  TRP B CH2 1 
ATOM   3850  N N   . THR B 1 95  ? 115.000 94.514  134.538 1.00 47.71 ? 95  THR B N   1 
ATOM   3851  C CA  . THR B 1 95  ? 114.416 93.203  134.767 1.00 47.71 ? 95  THR B CA  1 
ATOM   3852  C C   . THR B 1 95  ? 113.023 93.304  135.372 1.00 47.71 ? 95  THR B C   1 
ATOM   3853  O O   . THR B 1 95  ? 112.636 94.318  135.949 1.00 47.71 ? 95  THR B O   1 
ATOM   3854  C CB  . THR B 1 95  ? 115.308 92.385  135.688 1.00 47.71 ? 95  THR B CB  1 
ATOM   3855  O OG1 . THR B 1 95  ? 115.217 92.907  137.016 1.00 47.71 ? 95  THR B OG1 1 
ATOM   3856  C CG2 . THR B 1 95  ? 116.744 92.468  135.225 1.00 47.71 ? 95  THR B CG2 1 
ATOM   3857  N N   . SER B 1 96  ? 112.275 92.217  135.244 1.00 51.53 ? 96  SER B N   1 
ATOM   3858  C CA  . SER B 1 96  ? 110.889 92.141  135.680 1.00 51.53 ? 96  SER B CA  1 
ATOM   3859  C C   . SER B 1 96  ? 110.380 90.709  135.577 1.00 51.53 ? 96  SER B C   1 
ATOM   3860  O O   . SER B 1 96  ? 110.873 89.934  134.750 1.00 51.53 ? 96  SER B O   1 
ATOM   3861  C CB  . SER B 1 96  ? 110.013 93.067  134.837 1.00 51.53 ? 96  SER B CB  1 
ATOM   3862  O OG  . SER B 1 96  ? 108.650 92.944  135.185 1.00 51.53 ? 96  SER B OG  1 
ATOM   3863  N N   . PRO B 1 97  ? 109.403 90.315  136.396 1.00 52.31 ? 97  PRO B N   1 
ATOM   3864  C CA  . PRO B 1 97  ? 108.736 89.027  136.179 1.00 52.31 ? 97  PRO B CA  1 
ATOM   3865  C C   . PRO B 1 97  ? 107.655 89.069  135.116 1.00 52.31 ? 97  PRO B C   1 
ATOM   3866  O O   . PRO B 1 97  ? 107.008 88.041  134.878 1.00 52.31 ? 97  PRO B O   1 
ATOM   3867  C CB  . PRO B 1 97  ? 108.127 88.712  137.554 1.00 52.31 ? 97  PRO B CB  1 
ATOM   3868  C CG  . PRO B 1 97  ? 108.642 89.763  138.485 1.00 52.31 ? 97  PRO B CG  1 
ATOM   3869  C CD  . PRO B 1 97  ? 108.973 90.936  137.652 1.00 52.31 ? 97  PRO B CD  1 
ATOM   3870  N N   . PHE B 1 98  ? 107.421 90.210  134.492 1.00 52.25 ? 98  PHE B N   1 
ATOM   3871  C CA  . PHE B 1 98  ? 106.463 90.344  133.413 1.00 52.25 ? 98  PHE B CA  1 
ATOM   3872  C C   . PHE B 1 98  ? 107.180 90.586  132.097 1.00 52.25 ? 98  PHE B C   1 
ATOM   3873  O O   . PHE B 1 98  ? 108.347 90.987  132.077 1.00 52.25 ? 98  PHE B O   1 
ATOM   3874  C CB  . PHE B 1 98  ? 105.502 91.497  133.698 1.00 52.25 ? 98  PHE B CB  1 
ATOM   3875  C CG  . PHE B 1 98  ? 105.074 91.581  135.123 1.00 52.25 ? 98  PHE B CG  1 
ATOM   3876  C CD1 . PHE B 1 98  ? 104.419 90.528  135.720 1.00 52.25 ? 98  PHE B CD1 1 
ATOM   3877  C CD2 . PHE B 1 98  ? 105.322 92.714  135.866 1.00 52.25 ? 98  PHE B CD2 1 
ATOM   3878  C CE1 . PHE B 1 98  ? 104.021 90.605  137.031 1.00 52.25 ? 98  PHE B CE1 1 
ATOM   3879  C CE2 . PHE B 1 98  ? 104.925 92.796  137.178 1.00 52.25 ? 98  PHE B CE2 1 
ATOM   3880  C CZ  . PHE B 1 98  ? 104.276 91.742  137.761 1.00 52.25 ? 98  PHE B CZ  1 
ATOM   3881  N N   . PRO B 1 99  ? 106.521 90.338  130.971 1.00 50.15 ? 99  PRO B N   1 
ATOM   3882  C CA  . PRO B 1 99  ? 107.137 90.630  129.680 1.00 50.15 ? 99  PRO B CA  1 
ATOM   3883  C C   . PRO B 1 99  ? 107.283 92.125  129.475 1.00 50.15 ? 99  PRO B C   1 
ATOM   3884  O O   . PRO B 1 99  ? 106.525 92.918  130.053 1.00 50.15 ? 99  PRO B O   1 
ATOM   3885  C CB  . PRO B 1 99  ? 106.151 90.020  128.675 1.00 50.15 ? 99  PRO B CB  1 
ATOM   3886  C CG  . PRO B 1 99  ? 104.870 89.934  129.409 1.00 50.15 ? 99  PRO B CG  1 
ATOM   3887  C CD  . PRO B 1 99  ? 105.240 89.632  130.815 1.00 50.15 ? 99  PRO B CD  1 
ATOM   3888  N N   . PRO B 1 100 ? 108.244 92.549  128.661 1.00 45.97 ? 100 PRO B N   1 
ATOM   3889  C CA  . PRO B 1 100 ? 108.460 93.985  128.456 1.00 45.97 ? 100 PRO B CA  1 
ATOM   3890  C C   . PRO B 1 100 ? 107.250 94.653  127.826 1.00 45.97 ? 100 PRO B C   1 
ATOM   3891  O O   . PRO B 1 100 ? 106.472 94.028  127.105 1.00 45.97 ? 100 PRO B O   1 
ATOM   3892  C CB  . PRO B 1 100 ? 109.670 94.031  127.520 1.00 45.97 ? 100 PRO B CB  1 
ATOM   3893  C CG  . PRO B 1 100 ? 110.315 92.719  127.669 1.00 45.97 ? 100 PRO B CG  1 
ATOM   3894  C CD  . PRO B 1 100 ? 109.236 91.737  127.951 1.00 45.97 ? 100 PRO B CD  1 
ATOM   3895  N N   . GLY B 1 101 ? 107.094 95.936  128.113 1.00 42.44 ? 101 GLY B N   1 
ATOM   3896  C CA  . GLY B 1 101 ? 106.005 96.699  127.570 1.00 42.44 ? 101 GLY B CA  1 
ATOM   3897  C C   . GLY B 1 101 ? 104.986 97.028  128.629 1.00 42.44 ? 101 GLY B C   1 
ATOM   3898  O O   . GLY B 1 101 ? 105.258 96.986  129.829 1.00 42.44 ? 101 GLY B O   1 
ATOM   3899  N N   . PRO B 1 102 ? 103.786 97.376  128.194 1.00 39.74 ? 102 PRO B N   1 
ATOM   3900  C CA  . PRO B 1 102 ? 102.710 97.659  129.143 1.00 39.74 ? 102 PRO B CA  1 
ATOM   3901  C C   . PRO B 1 102 ? 102.469 96.486  130.075 1.00 39.74 ? 102 PRO B C   1 
ATOM   3902  O O   . PRO B 1 102 ? 102.701 95.330  129.724 1.00 39.74 ? 102 PRO B O   1 
ATOM   3903  C CB  . PRO B 1 102 ? 101.505 97.904  128.238 1.00 39.74 ? 102 PRO B CB  1 
ATOM   3904  C CG  . PRO B 1 102 ? 102.090 98.321  126.955 1.00 39.74 ? 102 PRO B CG  1 
ATOM   3905  C CD  . PRO B 1 102 ? 103.388 97.630  126.806 1.00 39.74 ? 102 PRO B CD  1 
ATOM   3906  N N   . LEU B 1 103 ? 102.006 96.796  131.281 1.00 42.44 ? 103 LEU B N   1 
ATOM   3907  C CA  . LEU B 1 103 ? 101.549 95.739  132.166 1.00 42.44 ? 103 LEU B CA  1 
ATOM   3908  C C   . LEU B 1 103 ? 100.197 95.217  131.730 1.00 42.44 ? 103 LEU B C   1 
ATOM   3909  O O   . LEU B 1 103 ? 99.817  94.103  132.099 1.00 42.44 ? 103 LEU B O   1 
ATOM   3910  C CB  . LEU B 1 103 ? 101.469 96.238  133.602 1.00 42.44 ? 103 LEU B CB  1 
ATOM   3911  C CG  . LEU B 1 103 ? 102.770 96.717  134.232 1.00 42.44 ? 103 LEU B CG  1 
ATOM   3912  C CD1 . LEU B 1 103 ? 102.527 97.125  135.665 1.00 42.44 ? 103 LEU B CD1 1 
ATOM   3913  C CD2 . LEU B 1 103 ? 103.822 95.648  134.152 1.00 42.44 ? 103 LEU B CD2 1 
ATOM   3914  N N   . GLU B 1 104 ? 99.465  95.999  130.949 1.00 49.03 ? 104 GLU B N   1 
ATOM   3915  C CA  . GLU B 1 104 ? 98.119  95.626  130.542 1.00 49.03 ? 104 GLU B CA  1 
ATOM   3916  C C   . GLU B 1 104 ? 97.573  96.701  129.618 1.00 49.03 ? 104 GLU B C   1 
ATOM   3917  O O   . GLU B 1 104 ? 98.155  97.776  129.468 1.00 49.03 ? 104 GLU B O   1 
ATOM   3918  C CB  . GLU B 1 104 ? 97.209  95.465  131.749 1.00 49.03 ? 104 GLU B CB  1 
ATOM   3919  C CG  . GLU B 1 104 ? 97.177  96.725  132.564 1.00 49.03 ? 104 GLU B CG  1 
ATOM   3920  C CD  . GLU B 1 104 ? 96.268  96.633  133.746 1.00 49.03 ? 104 GLU B CD  1 
ATOM   3921  O OE1 . GLU B 1 104 ? 96.264  95.593  134.427 1.00 49.03 ? 104 GLU B OE1 1 
ATOM   3922  O OE2 . GLU B 1 104 ? 95.531  97.604  133.984 1.00 49.03 ? 104 GLU B OE2 1 
ATOM   3923  N N   . ALA B 1 105 ? 96.451  96.380  128.987 1.00 46.68 ? 105 ALA B N   1 
ATOM   3924  C CA  . ALA B 1 105 ? 95.622  97.335  128.270 1.00 46.68 ? 105 ALA B CA  1 
ATOM   3925  C C   . ALA B 1 105 ? 94.214  97.083  128.760 1.00 46.68 ? 105 ALA B C   1 
ATOM   3926  O O   . ALA B 1 105 ? 93.685  95.987  128.583 1.00 46.68 ? 105 ALA B O   1 
ATOM   3927  C CB  . ALA B 1 105 ? 95.726  97.158  126.758 1.00 46.68 ? 105 ALA B CB  1 
ATOM   3928  N N   . SER B 1 106 ? 93.617  98.080  129.376 1.00 50.10 ? 106 SER B N   1 
ATOM   3929  C CA  . SER B 1 106 ? 92.679  97.847  130.460 1.00 50.10 ? 106 SER B CA  1 
ATOM   3930  C C   . SER B 1 106 ? 91.240  98.191  130.101 1.00 50.10 ? 106 SER B C   1 
ATOM   3931  O O   . SER B 1 106 ? 90.529  98.802  130.900 1.00 50.10 ? 106 SER B O   1 
ATOM   3932  C CB  . SER B 1 106 ? 93.120  98.626  131.691 1.00 50.10 ? 106 SER B CB  1 
ATOM   3933  O OG  . SER B 1 106 ? 94.431  98.262  132.088 1.00 50.10 ? 106 SER B OG  1 
ATOM   3934  N N   . VAL B 1 107 ? 90.793  97.808  128.910 1.00 55.50 ? 107 VAL B N   1 
ATOM   3935  C CA  . VAL B 1 107 ? 89.422  98.089  128.499 1.00 55.50 ? 107 VAL B CA  1 
ATOM   3936  C C   . VAL B 1 107 ? 88.466  97.602  129.575 1.00 55.50 ? 107 VAL B C   1 
ATOM   3937  O O   . VAL B 1 107 ? 88.385  96.402  129.855 1.00 55.50 ? 107 VAL B O   1 
ATOM   3938  C CB  . VAL B 1 107 ? 89.085  97.431  127.152 1.00 55.50 ? 107 VAL B CB  1 
ATOM   3939  C CG1 . VAL B 1 107 ? 87.589  97.403  126.945 1.00 55.50 ? 107 VAL B CG1 1 
ATOM   3940  C CG2 . VAL B 1 107 ? 89.747  98.176  126.037 1.00 55.50 ? 107 VAL B CG2 1 
ATOM   3941  N N   . ASN B 1 108 ? 87.722  98.528  130.172 1.00 63.39 ? 108 ASN B N   1 
ATOM   3942  C CA  . ASN B 1 108 ? 86.782  98.205  131.230 1.00 63.39 ? 108 ASN B CA  1 
ATOM   3943  C C   . ASN B 1 108 ? 85.361  98.517  130.804 1.00 63.39 ? 108 ASN B C   1 
ATOM   3944  O O   . ASN B 1 108 ? 85.107  99.510  130.109 1.00 63.39 ? 108 ASN B O   1 
ATOM   3945  C CB  . ASN B 1 108 ? 87.088  98.975  132.500 1.00 63.39 ? 108 ASN B CB  1 
ATOM   3946  C CG  . ASN B 1 108 ? 85.967  98.893  133.501 1.00 63.39 ? 108 ASN B CG  1 
ATOM   3947  O OD1 . ASN B 1 108 ? 85.150  97.975  133.464 1.00 63.39 ? 108 ASN B OD1 1 
ATOM   3948  N ND2 . ASN B 1 108 ? 85.899  99.869  134.387 1.00 63.39 ? 108 ASN B ND2 1 
ATOM   3949  N N   . TYR B 1 109 ? 84.440  97.682  131.279 1.00 68.33 ? 109 TYR B N   1 
ATOM   3950  C CA  . TYR B 1 109 ? 83.024  97.742  130.948 1.00 68.33 ? 109 TYR B CA  1 
ATOM   3951  C C   . TYR B 1 109 ? 82.235  97.977  132.225 1.00 68.33 ? 109 TYR B C   1 
ATOM   3952  O O   . TYR B 1 109 ? 82.511  97.346  133.249 1.00 68.33 ? 109 TYR B O   1 
ATOM   3953  C CB  . TYR B 1 109 ? 82.556  96.441  130.276 1.00 68.33 ? 109 TYR B CB  1 
ATOM   3954  C CG  . TYR B 1 109 ? 83.522  95.893  129.252 1.00 68.33 ? 109 TYR B CG  1 
ATOM   3955  C CD1 . TYR B 1 109 ? 84.648  95.179  129.635 1.00 68.33 ? 109 TYR B CD1 1 
ATOM   3956  C CD2 . TYR B 1 109 ? 83.313  96.096  127.904 1.00 68.33 ? 109 TYR B CD2 1 
ATOM   3957  C CE1 . TYR B 1 109 ? 85.530  94.695  128.700 1.00 68.33 ? 109 TYR B CE1 1 
ATOM   3958  C CE2 . TYR B 1 109 ? 84.184  95.606  126.967 1.00 68.33 ? 109 TYR B CE2 1 
ATOM   3959  C CZ  . TYR B 1 109 ? 85.288  94.912  127.366 1.00 68.33 ? 109 TYR B CZ  1 
ATOM   3960  O OH  . TYR B 1 109 ? 86.152  94.437  126.415 1.00 68.33 ? 109 TYR B OH  1 
ATOM   3961  N N   . GLN B 1 110 ? 81.259  98.879  132.172 1.00 74.32 ? 110 GLN B N   1 
ATOM   3962  C CA  . GLN B 1 110 ? 80.345  99.054  133.287 1.00 74.32 ? 110 GLN B CA  1 
ATOM   3963  C C   . GLN B 1 110 ? 78.933  99.084  132.731 1.00 74.32 ? 110 GLN B C   1 
ATOM   3964  O O   . GLN B 1 110 ? 78.705  98.809  131.551 1.00 74.32 ? 110 GLN B O   1 
ATOM   3965  C CB  . GLN B 1 110 ? 80.670  100.321 134.084 1.00 74.32 ? 110 GLN B CB  1 
ATOM   3966  C CG  . GLN B 1 110 ? 82.130  100.483 134.433 1.00 74.32 ? 110 GLN B CG  1 
ATOM   3967  C CD  . GLN B 1 110 ? 82.472  101.902 134.798 1.00 74.32 ? 110 GLN B CD  1 
ATOM   3968  O OE1 . GLN B 1 110 ? 81.941  102.452 135.761 1.00 74.32 ? 110 GLN B OE1 1 
ATOM   3969  N NE2 . GLN B 1 110 ? 83.356  102.514 134.021 1.00 74.32 ? 110 GLN B NE2 1 
ATOM   3970  N N   . ALA B 1 111 ? 77.981  99.430  133.588 1.00 78.41 ? 111 ALA B N   1 
ATOM   3971  C CA  . ALA B 1 111 ? 76.581  99.425  133.203 1.00 78.41 ? 111 ALA B CA  1 
ATOM   3972  C C   . ALA B 1 111 ? 76.301  100.469 132.128 1.00 78.41 ? 111 ALA B C   1 
ATOM   3973  O O   . ALA B 1 111 ? 77.067  101.412 131.919 1.00 78.41 ? 111 ALA B O   1 
ATOM   3974  C CB  . ALA B 1 111 ? 75.689  99.687  134.416 1.00 78.41 ? 111 ALA B CB  1 
ATOM   3975  N N   . GLY B 1 112 ? 75.175  100.283 131.447 1.00 81.52 ? 112 GLY B N   1 
ATOM   3976  C CA  . GLY B 1 112 ? 74.716  101.244 130.459 1.00 81.52 ? 112 GLY B CA  1 
ATOM   3977  C C   . GLY B 1 112 ? 75.650  101.408 129.281 1.00 81.52 ? 112 GLY B C   1 
ATOM   3978  O O   . GLY B 1 112 ? 75.684  102.480 128.664 1.00 81.52 ? 112 GLY B O   1 
ATOM   3979  N N   . GLU B 1 113 ? 76.409  100.364 128.953 1.00 82.01 ? 113 GLU B N   1 
ATOM   3980  C CA  . GLU B 1 113 ? 77.351  100.398 127.836 1.00 82.01 ? 113 GLU B CA  1 
ATOM   3981  C C   . GLU B 1 113 ? 78.326  101.566 127.963 1.00 82.01 ? 113 GLU B C   1 
ATOM   3982  O O   . GLU B 1 113 ? 78.582  102.294 127.003 1.00 82.01 ? 113 GLU B O   1 
ATOM   3983  C CB  . GLU B 1 113 ? 76.617  100.443 126.496 1.00 82.01 ? 113 GLU B CB  1 
ATOM   3984  C CG  . GLU B 1 113 ? 75.965  99.127  126.115 1.00 82.01 ? 113 GLU B CG  1 
ATOM   3985  C CD  . GLU B 1 113 ? 74.702  99.316  125.305 1.00 82.01 ? 113 GLU B CD  1 
ATOM   3986  O OE1 . GLU B 1 113 ? 74.381  100.473 124.964 1.00 82.01 ? 113 GLU B OE1 1 
ATOM   3987  O OE2 . GLU B 1 113 ? 74.025  98.307  125.014 1.00 82.01 ? 113 GLU B OE2 1 
ATOM   3988  N N   . SER B 1 114 ? 78.864  101.755 129.166 1.00 75.21 ? 114 SER B N   1 
ATOM   3989  C CA  . SER B 1 114 ? 79.939  102.715 129.403 1.00 75.21 ? 114 SER B CA  1 
ATOM   3990  C C   . SER B 1 114 ? 81.243  101.928 129.432 1.00 75.21 ? 114 SER B C   1 
ATOM   3991  O O   . SER B 1 114 ? 81.548  101.232 130.405 1.00 75.21 ? 114 SER B O   1 
ATOM   3992  C CB  . SER B 1 114 ? 79.712  103.497 130.690 1.00 75.21 ? 114 SER B CB  1 
ATOM   3993  O OG  . SER B 1 114 ? 79.743  102.639 131.812 1.00 75.21 ? 114 SER B OG  1 
ATOM   3994  N N   . SER B 1 115 ? 81.991  102.014 128.342 1.00 64.92 ? 115 SER B N   1 
ATOM   3995  C CA  . SER B 1 115 ? 83.284  101.375 128.210 1.00 64.92 ? 115 SER B CA  1 
ATOM   3996  C C   . SER B 1 115 ? 84.359  102.445 128.180 1.00 64.92 ? 115 SER B C   1 
ATOM   3997  O O   . SER B 1 115 ? 84.140  103.547 127.675 1.00 64.92 ? 115 SER B O   1 
ATOM   3998  C CB  . SER B 1 115 ? 83.353  100.548 126.935 1.00 64.92 ? 115 SER B CB  1 
ATOM   3999  O OG  . SER B 1 115 ? 82.386  99.519  126.953 1.00 64.92 ? 115 SER B OG  1 
ATOM   4000  N N   . MET B 1 116 ? 85.527  102.122 128.719 1.00 55.27 ? 116 MET B N   1 
ATOM   4001  C CA  . MET B 1 116 ? 86.615  103.073 128.581 1.00 55.27 ? 116 MET B CA  1 
ATOM   4002  C C   . MET B 1 116 ? 87.950  102.353 128.555 1.00 55.27 ? 116 MET B C   1 
ATOM   4003  O O   . MET B 1 116 ? 88.091  101.243 129.072 1.00 55.27 ? 116 MET B O   1 
ATOM   4004  C CB  . MET B 1 116 ? 86.584  104.133 129.679 1.00 55.27 ? 116 MET B CB  1 
ATOM   4005  C CG  . MET B 1 116 ? 86.655  103.620 131.078 1.00 55.27 ? 116 MET B CG  1 
ATOM   4006  S SD  . MET B 1 116 ? 87.282  104.921 132.163 1.00 55.27 ? 116 MET B SD  1 
ATOM   4007  C CE  . MET B 1 116 ? 88.874  105.257 131.411 1.00 55.27 ? 116 MET B CE  1 
ATOM   4008  N N   . PHE B 1 117 ? 88.920  103.003 127.927 1.00 44.72 ? 117 PHE B N   1 
ATOM   4009  C CA  . PHE B 1 117 ? 90.235  102.441 127.685 1.00 44.72 ? 117 PHE B CA  1 
ATOM   4010  C C   . PHE B 1 117 ? 91.202  102.991 128.714 1.00 44.72 ? 117 PHE B C   1 
ATOM   4011  O O   . PHE B 1 117 ? 91.232  104.197 128.981 1.00 44.72 ? 117 PHE B O   1 
ATOM   4012  C CB  . PHE B 1 117 ? 90.706  102.771 126.270 1.00 44.72 ? 117 PHE B CB  1 
ATOM   4013  C CG  . PHE B 1 117 ? 92.060  102.219 125.917 1.00 44.72 ? 117 PHE B CG  1 
ATOM   4014  C CD1 . PHE B 1 117 ? 92.207  100.916 125.500 1.00 44.72 ? 117 PHE B CD1 1 
ATOM   4015  C CD2 . PHE B 1 117 ? 93.180  103.023 125.958 1.00 44.72 ? 117 PHE B CD2 1 
ATOM   4016  C CE1 . PHE B 1 117 ? 93.443  100.425 125.169 1.00 44.72 ? 117 PHE B CE1 1 
ATOM   4017  C CE2 . PHE B 1 117 ? 94.414  102.533 125.620 1.00 44.72 ? 117 PHE B CE2 1 
ATOM   4018  C CZ  . PHE B 1 117 ? 94.545  101.238 125.228 1.00 44.72 ? 117 PHE B CZ  1 
ATOM   4019  N N   . ARG B 1 118 ? 91.968  102.097 129.307 1.00 52.75 ? 118 ARG B N   1 
ATOM   4020  C CA  . ARG B 1 118 ? 92.930  102.423 130.333 1.00 52.75 ? 118 ARG B CA  1 
ATOM   4021  C C   . ARG B 1 118 ? 94.234  101.765 129.942 1.00 52.75 ? 118 ARG B C   1 
ATOM   4022  O O   . ARG B 1 118 ? 94.277  100.881 129.089 1.00 52.75 ? 118 ARG B O   1 
ATOM   4023  C CB  . ARG B 1 118 ? 92.474  101.931 131.708 1.00 52.75 ? 118 ARG B CB  1 
ATOM   4024  C CG  . ARG B 1 118 ? 91.180  102.511 132.187 1.00 52.75 ? 118 ARG B CG  1 
ATOM   4025  C CD  . ARG B 1 118 ? 90.760  101.872 133.486 1.00 52.75 ? 118 ARG B CD  1 
ATOM   4026  N NE  . ARG B 1 118 ? 89.890  102.759 134.249 1.00 52.75 ? 118 ARG B NE  1 
ATOM   4027  C CZ  . ARG B 1 118 ? 88.568  102.676 134.268 1.00 52.75 ? 118 ARG B CZ  1 
ATOM   4028  N NH1 . ARG B 1 118 ? 87.960  101.735 133.575 1.00 52.75 ? 118 ARG B NH1 1 
ATOM   4029  N NH2 . ARG B 1 118 ? 87.856  103.527 134.990 1.00 52.75 ? 118 ARG B NH2 1 
ATOM   4030  N N   . PHE B 1 119 ? 95.308  102.182 130.579 1.00 42.77 ? 119 PHE B N   1 
ATOM   4031  C CA  . PHE B 1 119 ? 96.597  101.719 130.103 1.00 42.77 ? 119 PHE B CA  1 
ATOM   4032  C C   . PHE B 1 119 ? 97.619  101.844 131.212 1.00 42.77 ? 119 PHE B C   1 
ATOM   4033  O O   . PHE B 1 119 ? 97.928  102.953 131.633 1.00 42.77 ? 119 PHE B O   1 
ATOM   4034  C CB  . PHE B 1 119 ? 96.990  102.523 128.892 1.00 42.77 ? 119 PHE B CB  1 
ATOM   4035  C CG  . PHE B 1 119 ? 98.378  102.319 128.486 1.00 42.77 ? 119 PHE B CG  1 
ATOM   4036  C CD1 . PHE B 1 119 ? 98.786  101.095 128.042 1.00 42.77 ? 119 PHE B CD1 1 
ATOM   4037  C CD2 . PHE B 1 119 ? 99.280  103.353 128.526 1.00 42.77 ? 119 PHE B CD2 1 
ATOM   4038  C CE1 . PHE B 1 119 ? 100.070 100.896 127.667 1.00 42.77 ? 119 PHE B CE1 1 
ATOM   4039  C CE2 . PHE B 1 119 ? 100.571 103.158 128.147 1.00 42.77 ? 119 PHE B CE2 1 
ATOM   4040  C CZ  . PHE B 1 119 ? 100.968 101.929 127.714 1.00 42.77 ? 119 PHE B CZ  1 
ATOM   4041  N N   . THR B 1 120 ? 98.139  100.721 131.686 1.00 41.71 ? 120 THR B N   1 
ATOM   4042  C CA  . THR B 1 120 ? 99.112  100.720 132.766 1.00 41.71 ? 120 THR B CA  1 
ATOM   4043  C C   . THR B 1 120 ? 100.498 100.537 132.183 1.00 41.71 ? 120 THR B C   1 
ATOM   4044  O O   . THR B 1 120 ? 100.691 99.718  131.286 1.00 41.71 ? 120 THR B O   1 
ATOM   4045  C CB  . THR B 1 120 ? 98.825  99.611  133.774 1.00 41.71 ? 120 THR B CB  1 
ATOM   4046  O OG1 . THR B 1 120 ? 97.492  99.752  134.269 1.00 41.71 ? 120 THR B OG1 1 
ATOM   4047  C CG2 . THR B 1 120 ? 99.781  99.697  134.938 1.00 41.71 ? 120 THR B CG2 1 
ATOM   4048  N N   . ILE B 1 121 ? 101.455 101.295 132.688 1.00 39.64 ? 121 ILE B N   1 
ATOM   4049  C CA  . ILE B 1 121 ? 102.841 101.116 132.306 1.00 39.64 ? 121 ILE B CA  1 
ATOM   4050  C C   . ILE B 1 121 ? 103.718 101.444 133.501 1.00 39.64 ? 121 ILE B C   1 
ATOM   4051  O O   . ILE B 1 121 ? 103.414 102.347 134.287 1.00 39.64 ? 121 ILE B O   1 
ATOM   4052  C CB  . ILE B 1 121 ? 103.211 101.977 131.084 1.00 39.64 ? 121 ILE B CB  1 
ATOM   4053  C CG1 . ILE B 1 121 ? 104.658 101.730 130.678 1.00 39.64 ? 121 ILE B CG1 1 
ATOM   4054  C CG2 . ILE B 1 121 ? 102.988 103.436 131.349 1.00 39.64 ? 121 ILE B CG2 1 
ATOM   4055  C CD1 . ILE B 1 121 ? 105.038 102.383 129.397 1.00 39.64 ? 121 ILE B CD1 1 
ATOM   4056  N N   . GLU B 1 122 ? 104.774 100.684 133.660 1.00 41.46 ? 122 GLU B N   1 
ATOM   4057  C CA  . GLU B 1 122 ? 105.831 101.075 134.566 1.00 41.46 ? 122 GLU B CA  1 
ATOM   4058  C C   . GLU B 1 122 ? 106.809 101.878 133.724 1.00 41.46 ? 122 GLU B C   1 
ATOM   4059  O O   . GLU B 1 122 ? 107.583 101.295 132.959 1.00 41.46 ? 122 GLU B O   1 
ATOM   4060  C CB  . GLU B 1 122 ? 106.470 99.844  135.211 1.00 41.46 ? 122 GLU B CB  1 
ATOM   4061  C CG  . GLU B 1 122 ? 107.344 100.110 136.428 1.00 41.46 ? 122 GLU B CG  1 
ATOM   4062  C CD  . GLU B 1 122 ? 108.822 100.229 136.112 1.00 41.46 ? 122 GLU B CD  1 
ATOM   4063  O OE1 . GLU B 1 122 ? 109.288 99.566  135.167 1.00 41.46 ? 122 GLU B OE1 1 
ATOM   4064  O OE2 . GLU B 1 122 ? 109.528 100.978 136.821 1.00 41.46 ? 122 GLU B OE2 1 
ATOM   4065  N N   . PRO B 1 123 ? 106.773 103.212 133.797 1.00 39.88 ? 123 PRO B N   1 
ATOM   4066  C CA  . PRO B 1 123 ? 107.641 104.018 132.938 1.00 39.88 ? 123 PRO B CA  1 
ATOM   4067  C C   . PRO B 1 123 ? 109.085 103.602 133.056 1.00 39.88 ? 123 PRO B C   1 
ATOM   4068  O O   . PRO B 1 123 ? 109.642 103.586 134.152 1.00 39.88 ? 123 PRO B O   1 
ATOM   4069  C CB  . PRO B 1 123 ? 107.427 105.438 133.462 1.00 39.88 ? 123 PRO B CB  1 
ATOM   4070  C CG  . PRO B 1 123 ? 106.112 105.407 134.079 1.00 39.88 ? 123 PRO B CG  1 
ATOM   4071  C CD  . PRO B 1 123 ? 105.946 104.057 134.669 1.00 39.88 ? 123 PRO B CD  1 
ATOM   4072  N N   . VAL B 1 124 ? 109.686 103.236 131.934 1.00 37.74 ? 124 VAL B N   1 
ATOM   4073  C CA  . VAL B 1 124 ? 111.063 102.780 131.887 1.00 37.74 ? 124 VAL B CA  1 
ATOM   4074  C C   . VAL B 1 124 ? 111.853 103.770 131.053 1.00 37.74 ? 124 VAL B C   1 
ATOM   4075  O O   . VAL B 1 124 ? 111.458 104.095 129.932 1.00 37.74 ? 124 VAL B O   1 
ATOM   4076  C CB  . VAL B 1 124 ? 111.165 101.365 131.300 1.00 37.74 ? 124 VAL B CB  1 
ATOM   4077  C CG1 . VAL B 1 124 ? 112.595 100.979 131.115 1.00 37.74 ? 124 VAL B CG1 1 
ATOM   4078  C CG2 . VAL B 1 124 ? 110.499 100.395 132.201 1.00 37.74 ? 124 VAL B CG2 1 
ATOM   4079  N N   . GLY B 1 125 ? 112.949 104.260 131.599 1.00 38.77 ? 125 GLY B N   1 
ATOM   4080  C CA  . GLY B 1 125 ? 113.827 105.098 130.833 1.00 38.77 ? 125 GLY B CA  1 
ATOM   4081  C C   . GLY B 1 125 ? 114.496 104.281 129.759 1.00 38.77 ? 125 GLY B C   1 
ATOM   4082  O O   . GLY B 1 125 ? 114.621 103.062 129.874 1.00 38.77 ? 125 GLY B O   1 
ATOM   4083  N N   . PRO B 1 126 ? 114.945 104.930 128.688 1.00 38.64 ? 126 PRO B N   1 
ATOM   4084  C CA  . PRO B 1 126 ? 115.654 104.191 127.640 1.00 38.64 ? 126 PRO B CA  1 
ATOM   4085  C C   . PRO B 1 126 ? 116.889 103.491 128.144 1.00 38.64 ? 126 PRO B C   1 
ATOM   4086  O O   . PRO B 1 126 ? 117.415 102.618 127.449 1.00 38.64 ? 126 PRO B O   1 
ATOM   4087  C CB  . PRO B 1 126 ? 116.004 105.279 126.621 1.00 38.64 ? 126 PRO B CB  1 
ATOM   4088  C CG  . PRO B 1 126 ? 115.975 106.530 127.388 1.00 38.64 ? 126 PRO B CG  1 
ATOM   4089  C CD  . PRO B 1 126 ? 114.891 106.367 128.395 1.00 38.64 ? 126 PRO B CD  1 
ATOM   4090  N N   . HIS B 1 127 ? 117.368 103.841 129.337 1.00 43.87 ? 127 HIS B N   1 
ATOM   4091  C CA  . HIS B 1 127 ? 118.537 103.200 129.923 1.00 43.87 ? 127 HIS B CA  1 
ATOM   4092  C C   . HIS B 1 127 ? 118.287 102.771 131.361 1.00 43.87 ? 127 HIS B C   1 
ATOM   4093  O O   . HIS B 1 127 ? 119.237 102.627 132.127 1.00 43.87 ? 127 HIS B O   1 
ATOM   4094  C CB  . HIS B 1 127 ? 119.744 104.130 129.843 1.00 43.87 ? 127 HIS B CB  1 
ATOM   4095  C CG  . HIS B 1 127 ? 119.863 104.833 128.530 1.00 43.87 ? 127 HIS B CG  1 
ATOM   4096  N ND1 . HIS B 1 127 ? 120.054 104.160 127.345 1.00 43.87 ? 127 HIS B ND1 1 
ATOM   4097  C CD2 . HIS B 1 127 ? 119.805 106.146 128.212 1.00 43.87 ? 127 HIS B CD2 1 
ATOM   4098  C CE1 . HIS B 1 127 ? 120.112 105.029 126.352 1.00 43.87 ? 127 HIS B CE1 1 
ATOM   4099  N NE2 . HIS B 1 127 ? 119.963 106.241 126.852 1.00 43.87 ? 127 HIS B NE2 1 
ATOM   4100  N N   . ALA B 1 128 ? 117.032 102.562 131.739 1.00 43.22 ? 128 ALA B N   1 
ATOM   4101  C CA  . ALA B 1 128 ? 116.715 102.134 133.090 1.00 43.22 ? 128 ALA B CA  1 
ATOM   4102  C C   . ALA B 1 128 ? 117.247 100.735 133.343 1.00 43.22 ? 128 ALA B C   1 
ATOM   4103  O O   . ALA B 1 128 ? 117.253 99.881  132.459 1.00 43.22 ? 128 ALA B O   1 
ATOM   4104  C CB  . ALA B 1 128 ? 115.212 102.161 133.317 1.00 43.22 ? 128 ALA B CB  1 
ATOM   4105  N N   . GLY B 1 129 ? 117.688 100.498 134.569 1.00 45.15 ? 129 GLY B N   1 
ATOM   4106  C CA  . GLY B 1 129 ? 118.325 99.241  134.870 1.00 45.15 ? 129 GLY B CA  1 
ATOM   4107  C C   . GLY B 1 129 ? 119.751 99.137  134.402 1.00 45.15 ? 129 GLY B C   1 
ATOM   4108  O O   . GLY B 1 129 ? 120.310 98.037  134.409 1.00 45.15 ? 129 GLY B O   1 
ATOM   4109  N N   . THR B 1 130 ? 120.350 100.240 133.990 1.00 46.63 ? 130 THR B N   1 
ATOM   4110  C CA  . THR B 1 130 ? 121.743 100.329 133.599 1.00 46.63 ? 130 THR B CA  1 
ATOM   4111  C C   . THR B 1 130 ? 122.439 101.332 134.505 1.00 46.63 ? 130 THR B C   1 
ATOM   4112  O O   . THR B 1 130 ? 121.776 102.131 135.176 1.00 46.63 ? 130 THR B O   1 
ATOM   4113  C CB  . THR B 1 130 ? 121.862 100.761 132.133 1.00 46.63 ? 130 THR B CB  1 
ATOM   4114  O OG1 . THR B 1 130 ? 121.201 102.015 131.954 1.00 46.63 ? 130 THR B OG1 1 
ATOM   4115  C CG2 . THR B 1 130 ? 121.215 99.735  131.236 1.00 46.63 ? 130 THR B CG2 1 
ATOM   4116  N N   . PRO B 1 131 ? 123.772 101.322 134.562 1.00 49.88 ? 131 PRO B N   1 
ATOM   4117  C CA  . PRO B 1 131 ? 124.463 102.204 135.514 1.00 49.88 ? 131 PRO B CA  1 
ATOM   4118  C C   . PRO B 1 131 ? 124.199 103.676 135.295 1.00 49.88 ? 131 PRO B C   1 
ATOM   4119  O O   . PRO B 1 131 ? 124.596 104.485 136.138 1.00 49.88 ? 131 PRO B O   1 
ATOM   4120  C CB  . PRO B 1 131 ? 125.940 101.866 135.295 1.00 49.88 ? 131 PRO B CB  1 
ATOM   4121  C CG  . PRO B 1 131 ? 125.927 100.499 134.750 1.00 49.88 ? 131 PRO B CG  1 
ATOM   4122  C CD  . PRO B 1 131 ? 124.722 100.435 133.874 1.00 49.88 ? 131 PRO B CD  1 
ATOM   4123  N N   . ALA B 1 132 ? 123.554 104.057 134.193 1.00 48.10 ? 132 ALA B N   1 
ATOM   4124  C CA  . ALA B 1 132 ? 123.175 105.451 133.999 1.00 48.10 ? 132 ALA B CA  1 
ATOM   4125  C C   . ALA B 1 132 ? 121.829 105.772 134.631 1.00 48.10 ? 132 ALA B C   1 
ATOM   4126  O O   . ALA B 1 132 ? 121.569 106.935 134.953 1.00 48.10 ? 132 ALA B O   1 
ATOM   4127  C CB  . ALA B 1 132 ? 123.144 105.789 132.512 1.00 48.10 ? 132 ALA B CB  1 
ATOM   4128  N N   . ASP B 1 133 ? 120.966 104.776 134.811 1.00 47.07 ? 133 ASP B N   1 
ATOM   4129  C CA  . ASP B 1 133 ? 119.667 104.961 135.460 1.00 47.07 ? 133 ASP B CA  1 
ATOM   4130  C C   . ASP B 1 133 ? 119.320 103.704 136.241 1.00 47.07 ? 133 ASP B C   1 
ATOM   4131  O O   . ASP B 1 133 ? 118.365 102.992 135.915 1.00 47.07 ? 133 ASP B O   1 
ATOM   4132  C CB  . ASP B 1 133 ? 118.587 105.289 134.431 1.00 47.07 ? 133 ASP B CB  1 
ATOM   4133  C CG  . ASP B 1 133 ? 117.327 105.833 135.062 1.00 47.07 ? 133 ASP B CG  1 
ATOM   4134  O OD1 . ASP B 1 133 ? 117.245 105.860 136.304 1.00 47.07 ? 133 ASP B OD1 1 
ATOM   4135  O OD2 . ASP B 1 133 ? 116.415 106.240 134.314 1.00 47.07 ? 133 ASP B OD2 1 
ATOM   4136  N N   . PRO B 1 134 ? 120.069 103.412 137.306 1.00 46.33 ? 134 PRO B N   1 
ATOM   4137  C CA  . PRO B 1 134 ? 119.891 102.128 137.993 1.00 46.33 ? 134 PRO B CA  1 
ATOM   4138  C C   . PRO B 1 134 ? 118.555 101.963 138.683 1.00 46.33 ? 134 PRO B C   1 
ATOM   4139  O O   . PRO B 1 134 ? 118.182 100.826 138.987 1.00 46.33 ? 134 PRO B O   1 
ATOM   4140  C CB  . PRO B 1 134 ? 121.038 102.115 139.007 1.00 46.33 ? 134 PRO B CB  1 
ATOM   4141  C CG  . PRO B 1 134 ? 121.387 103.530 139.200 1.00 46.33 ? 134 PRO B CG  1 
ATOM   4142  C CD  . PRO B 1 134 ? 121.166 104.197 137.890 1.00 46.33 ? 134 PRO B CD  1 
ATOM   4143  N N   . VAL B 1 135 ? 117.817 103.036 138.948 1.00 46.72 ? 135 VAL B N   1 
ATOM   4144  C CA  . VAL B 1 135 ? 116.561 102.920 139.673 1.00 46.72 ? 135 VAL B CA  1 
ATOM   4145  C C   . VAL B 1 135 ? 115.389 103.491 138.897 1.00 46.72 ? 135 VAL B C   1 
ATOM   4146  O O   . VAL B 1 135 ? 114.299 103.618 139.448 1.00 46.72 ? 135 VAL B O   1 
ATOM   4147  C CB  . VAL B 1 135 ? 116.653 103.576 141.061 1.00 46.72 ? 135 VAL B CB  1 
ATOM   4148  C CG1 . VAL B 1 135 ? 117.434 102.690 141.994 1.00 46.72 ? 135 VAL B CG1 1 
ATOM   4149  C CG2 . VAL B 1 135 ? 117.307 104.925 140.946 1.00 46.72 ? 135 VAL B CG2 1 
ATOM   4150  N N   . ASN B 1 136 ? 115.591 103.849 137.632 1.00 43.37 ? 136 ASN B N   1 
ATOM   4151  C CA  . ASN B 1 136 ? 114.507 104.312 136.777 1.00 43.37 ? 136 ASN B CA  1 
ATOM   4152  C C   . ASN B 1 136 ? 113.783 105.495 137.421 1.00 43.37 ? 136 ASN B C   1 
ATOM   4153  O O   . ASN B 1 136 ? 112.585 105.456 137.699 1.00 43.37 ? 136 ASN B O   1 
ATOM   4154  C CB  . ASN B 1 136 ? 113.547 103.161 136.479 1.00 43.37 ? 136 ASN B CB  1 
ATOM   4155  C CG  . ASN B 1 136 ? 112.608 103.461 135.354 1.00 43.37 ? 136 ASN B CG  1 
ATOM   4156  O OD1 . ASN B 1 136 ? 112.970 104.123 134.391 1.00 43.37 ? 136 ASN B OD1 1 
ATOM   4157  N ND2 . ASN B 1 136 ? 111.388 102.972 135.464 1.00 43.37 ? 136 ASN B ND2 1 
ATOM   4158  N N   . GLU B 1 137 ? 114.540 106.561 137.655 1.00 48.49 ? 137 GLU B N   1 
ATOM   4159  C CA  . GLU B 1 137 ? 114.041 107.678 138.446 1.00 48.49 ? 137 GLU B CA  1 
ATOM   4160  C C   . GLU B 1 137 ? 113.286 108.717 137.626 1.00 48.49 ? 137 GLU B C   1 
ATOM   4161  O O   . GLU B 1 137 ? 112.253 109.222 138.074 1.00 48.49 ? 137 GLU B O   1 
ATOM   4162  C CB  . GLU B 1 137 ? 115.202 108.347 139.173 1.00 48.49 ? 137 GLU B CB  1 
ATOM   4163  C CG  . GLU B 1 137 ? 116.430 108.504 138.314 1.00 48.49 ? 137 GLU B CG  1 
ATOM   4164  C CD  . GLU B 1 137 ? 117.414 109.494 138.889 1.00 48.49 ? 137 GLU B CD  1 
ATOM   4165  O OE1 . GLU B 1 137 ? 117.070 110.174 139.876 1.00 48.49 ? 137 GLU B OE1 1 
ATOM   4166  O OE2 . GLU B 1 137 ? 118.533 109.596 138.351 1.00 48.49 ? 137 GLU B OE2 1 
ATOM   4167  N N   . LEU B 1 138 ? 113.776 109.051 136.435 1.00 44.29 ? 138 LEU B N   1 
ATOM   4168  C CA  . LEU B 1 138 ? 113.228 110.188 135.707 1.00 44.29 ? 138 LEU B CA  1 
ATOM   4169  C C   . LEU B 1 138 ? 111.950 109.839 134.967 1.00 44.29 ? 138 LEU B C   1 
ATOM   4170  O O   . LEU B 1 138 ? 111.036 110.660 134.907 1.00 44.29 ? 138 LEU B O   1 
ATOM   4171  C CB  . LEU B 1 138 ? 114.255 110.726 134.720 1.00 44.29 ? 138 LEU B CB  1 
ATOM   4172  C CG  . LEU B 1 138 ? 115.455 111.436 135.326 1.00 44.29 ? 138 LEU B CG  1 
ATOM   4173  C CD1 . LEU B 1 138 ? 116.247 112.102 134.238 1.00 44.29 ? 138 LEU B CD1 1 
ATOM   4174  C CD2 . LEU B 1 138 ? 114.998 112.452 136.340 1.00 44.29 ? 138 LEU B CD2 1 
ATOM   4175  N N   . ALA B 1 139 ? 111.872 108.631 134.409 1.00 42.71 ? 139 ALA B N   1 
ATOM   4176  C CA  . ALA B 1 139 ? 110.834 108.305 133.436 1.00 42.71 ? 139 ALA B CA  1 
ATOM   4177  C C   . ALA B 1 139 ? 109.453 108.736 133.896 1.00 42.71 ? 139 ALA B C   1 
ATOM   4178  O O   . ALA B 1 139 ? 108.695 109.331 133.125 1.00 42.71 ? 139 ALA B O   1 
ATOM   4179  C CB  . ALA B 1 139 ? 110.849 106.810 133.146 1.00 42.71 ? 139 ALA B CB  1 
ATOM   4180  N N   . ALA B 1 140 ? 109.113 108.467 135.154 1.00 42.37 ? 140 ALA B N   1 
ATOM   4181  C CA  . ALA B 1 140 ? 107.787 108.825 135.645 1.00 42.37 ? 140 ALA B CA  1 
ATOM   4182  C C   . ALA B 1 140 ? 107.590 110.333 135.659 1.00 42.37 ? 140 ALA B C   1 
ATOM   4183  O O   . ALA B 1 140 ? 106.525 110.832 135.280 1.00 42.37 ? 140 ALA B O   1 
ATOM   4184  C CB  . ALA B 1 140 ? 107.574 108.244 137.036 1.00 42.37 ? 140 ALA B CB  1 
ATOM   4185  N N   . LYS B 1 141 ? 108.616 111.076 136.071 1.00 44.63 ? 141 LYS B N   1 
ATOM   4186  C CA  . LYS B 1 141 ? 108.497 112.526 136.133 1.00 44.63 ? 141 LYS B CA  1 
ATOM   4187  C C   . LYS B 1 141 ? 108.472 113.143 134.744 1.00 44.63 ? 141 LYS B C   1 
ATOM   4188  O O   . LYS B 1 141 ? 107.744 114.107 134.507 1.00 44.63 ? 141 LYS B O   1 
ATOM   4189  C CB  . LYS B 1 141 ? 109.635 113.102 136.957 1.00 44.63 ? 141 LYS B CB  1 
ATOM   4190  C CG  . LYS B 1 141 ? 109.502 112.816 138.423 1.00 44.63 ? 141 LYS B CG  1 
ATOM   4191  C CD  . LYS B 1 141 ? 110.792 113.109 139.131 1.00 44.63 ? 141 LYS B CD  1 
ATOM   4192  C CE  . LYS B 1 141 ? 110.657 112.904 140.614 1.00 44.63 ? 141 LYS B CE  1 
ATOM   4193  N NZ  . LYS B 1 141 ? 111.987 112.989 141.263 1.00 44.63 ? 141 LYS B NZ  1 
ATOM   4194  N N   . GLN B 1 142 ? 109.270 112.615 133.819 1.00 43.26 ? 142 GLN B N   1 
ATOM   4195  C CA  . GLN B 1 142 ? 109.202 113.077 132.438 1.00 43.26 ? 142 GLN B CA  1 
ATOM   4196  C C   . GLN B 1 142 ? 107.825 112.832 131.849 1.00 43.26 ? 142 GLN B C   1 
ATOM   4197  O O   . GLN B 1 142 ? 107.285 113.687 131.145 1.00 43.26 ? 142 GLN B O   1 
ATOM   4198  C CB  . GLN B 1 142 ? 110.263 112.386 131.597 1.00 43.26 ? 142 GLN B CB  1 
ATOM   4199  C CG  . GLN B 1 142 ? 111.658 112.813 131.915 1.00 43.26 ? 142 GLN B CG  1 
ATOM   4200  C CD  . GLN B 1 142 ? 112.667 112.073 131.097 1.00 43.26 ? 142 GLN B CD  1 
ATOM   4201  O OE1 . GLN B 1 142 ? 112.336 111.110 130.419 1.00 43.26 ? 142 GLN B OE1 1 
ATOM   4202  N NE2 . GLN B 1 142 ? 113.909 112.513 131.148 1.00 43.26 ? 142 GLN B NE2 1 
ATOM   4203  N N   . LEU B 1 143 ? 107.244 111.668 132.118 1.00 44.33 ? 143 LEU B N   1 
ATOM   4204  C CA  . LEU B 1 143 ? 105.893 111.393 131.652 1.00 44.33 ? 143 LEU B CA  1 
ATOM   4205  C C   . LEU B 1 143 ? 104.901 112.380 132.252 1.00 44.33 ? 143 LEU B C   1 
ATOM   4206  O O   . LEU B 1 143 ? 104.061 112.940 131.540 1.00 44.33 ? 143 LEU B O   1 
ATOM   4207  C CB  . LEU B 1 143 ? 105.519 109.957 132.000 1.00 44.33 ? 143 LEU B CB  1 
ATOM   4208  C CG  . LEU B 1 143 ? 104.095 109.495 131.741 1.00 44.33 ? 143 LEU B CG  1 
ATOM   4209  C CD1 . LEU B 1 143 ? 103.773 109.632 130.292 1.00 44.33 ? 143 LEU B CD1 1 
ATOM   4210  C CD2 . LEU B 1 143 ? 103.949 108.064 132.161 1.00 44.33 ? 143 LEU B CD2 1 
ATOM   4211  N N   . MET B 1 144 ? 104.993 112.615 133.564 1.00 48.80 ? 144 MET B N   1 
ATOM   4212  C CA  . MET B 1 144 ? 104.099 113.562 134.229 1.00 48.80 ? 144 MET B CA  1 
ATOM   4213  C C   . MET B 1 144 ? 104.228 114.956 133.636 1.00 48.80 ? 144 MET B C   1 
ATOM   4214  O O   . MET B 1 144 ? 103.229 115.633 133.375 1.00 48.80 ? 144 MET B O   1 
ATOM   4215  C CB  . MET B 1 144 ? 104.406 113.609 135.723 1.00 48.80 ? 144 MET B CB  1 
ATOM   4216  C CG  . MET B 1 144 ? 103.985 112.391 136.501 1.00 48.80 ? 144 MET B CG  1 
ATOM   4217  S SD  . MET B 1 144 ? 103.844 112.737 138.262 1.00 48.80 ? 144 MET B SD  1 
ATOM   4218  C CE  . MET B 1 144 ? 102.639 114.056 138.260 1.00 48.80 ? 144 MET B CE  1 
ATOM   4219  N N   . GLN B 1 145 ? 105.463 115.404 133.430 1.00 46.82 ? 145 GLN B N   1 
ATOM   4220  C CA  . GLN B 1 145 ? 105.715 116.741 132.913 1.00 46.82 ? 145 GLN B CA  1 
ATOM   4221  C C   . GLN B 1 145 ? 105.211 116.891 131.489 1.00 46.82 ? 145 GLN B C   1 
ATOM   4222  O O   . GLN B 1 145 ? 104.545 117.874 131.157 1.00 46.82 ? 145 GLN B O   1 
ATOM   4223  C CB  . GLN B 1 145 ? 107.205 117.036 132.979 1.00 46.82 ? 145 GLN B CB  1 
ATOM   4224  C CG  . GLN B 1 145 ? 107.596 118.286 132.265 1.00 46.82 ? 145 GLN B CG  1 
ATOM   4225  C CD  . GLN B 1 145 ? 109.029 118.644 132.511 1.00 46.82 ? 145 GLN B CD  1 
ATOM   4226  O OE1 . GLN B 1 145 ? 109.710 117.993 133.294 1.00 46.82 ? 145 GLN B OE1 1 
ATOM   4227  N NE2 . GLN B 1 145 ? 109.507 119.676 131.831 1.00 46.82 ? 145 GLN B NE2 1 
ATOM   4228  N N   . ARG B 1 146 ? 105.561 115.946 130.623 1.00 49.10 ? 146 ARG B N   1 
ATOM   4229  C CA  . ARG B 1 146 ? 105.068 115.971 129.256 1.00 49.10 ? 146 ARG B CA  1 
ATOM   4230  C C   . ARG B 1 146 ? 103.554 115.988 129.232 1.00 49.10 ? 146 ARG B C   1 
ATOM   4231  O O   . ARG B 1 146 ? 102.944 116.721 128.451 1.00 49.10 ? 146 ARG B O   1 
ATOM   4232  C CB  . ARG B 1 146 ? 105.612 114.760 128.508 1.00 49.10 ? 146 ARG B CB  1 
ATOM   4233  C CG  . ARG B 1 146 ? 105.372 114.767 127.033 1.00 49.10 ? 146 ARG B CG  1 
ATOM   4234  C CD  . ARG B 1 146 ? 106.209 115.809 126.359 1.00 49.10 ? 146 ARG B CD  1 
ATOM   4235  N NE  . ARG B 1 146 ? 105.382 116.907 125.886 1.00 49.10 ? 146 ARG B NE  1 
ATOM   4236  C CZ  . ARG B 1 146 ? 105.843 117.937 125.192 1.00 49.10 ? 146 ARG B CZ  1 
ATOM   4237  N NH1 . ARG B 1 146 ? 107.130 118.006 124.889 1.00 49.10 ? 146 ARG B NH1 1 
ATOM   4238  N NH2 . ARG B 1 146 ? 105.017 118.894 124.803 1.00 49.10 ? 146 ARG B NH2 1 
ATOM   4239  N N   . LEU B 1 147 ? 102.928 115.211 130.106 1.00 47.62 ? 147 LEU B N   1 
ATOM   4240  C CA  . LEU B 1 147 ? 101.481 115.129 130.103 1.00 47.62 ? 147 LEU B CA  1 
ATOM   4241  C C   . LEU B 1 147 ? 100.850 116.421 130.611 1.00 47.62 ? 147 LEU B C   1 
ATOM   4242  O O   . LEU B 1 147 ? 99.765  116.802 130.161 1.00 47.62 ? 147 LEU B O   1 
ATOM   4243  C CB  . LEU B 1 147 ? 101.059 113.932 130.945 1.00 47.62 ? 147 LEU B CB  1 
ATOM   4244  C CG  . LEU B 1 147 ? 99.642  113.421 130.768 1.00 47.62 ? 147 LEU B CG  1 
ATOM   4245  C CD1 . LEU B 1 147 ? 99.533  112.869 129.383 1.00 47.62 ? 147 LEU B CD1 1 
ATOM   4246  C CD2 . LEU B 1 147 ? 99.342  112.358 131.780 1.00 47.62 ? 147 LEU B CD2 1 
ATOM   4247  N N   . GLY B 1 148 ? 101.511 117.114 131.537 1.00 52.07 ? 148 GLY B N   1 
ATOM   4248  C CA  . GLY B 1 148 ? 101.020 118.418 131.951 1.00 52.07 ? 148 GLY B CA  1 
ATOM   4249  C C   . GLY B 1 148 ? 101.215 119.476 130.882 1.00 52.07 ? 148 GLY B C   1 
ATOM   4250  O O   . GLY B 1 148 ? 100.373 120.358 130.706 1.00 52.07 ? 148 GLY B O   1 
ATOM   4251  N N   . GLN B 1 149 ? 102.328 119.402 130.157 1.00 49.89 ? 149 GLN B N   1 
ATOM   4252  C CA  . GLN B 1 149 ? 102.572 120.334 129.064 1.00 49.89 ? 149 GLN B CA  1 
ATOM   4253  C C   . GLN B 1 149 ? 101.558 120.149 127.945 1.00 49.89 ? 149 GLN B C   1 
ATOM   4254  O O   . GLN B 1 149 ? 101.132 121.123 127.318 1.00 49.89 ? 149 GLN B O   1 
ATOM   4255  C CB  . GLN B 1 149 ? 103.989 120.147 128.538 1.00 49.89 ? 149 GLN B CB  1 
ATOM   4256  C CG  . GLN B 1 149 ? 104.285 120.897 127.274 1.00 49.89 ? 149 GLN B CG  1 
ATOM   4257  C CD  . GLN B 1 149 ? 104.662 122.334 127.534 1.00 49.89 ? 149 GLN B CD  1 
ATOM   4258  O OE1 . GLN B 1 149 ? 104.975 122.710 128.660 1.00 49.89 ? 149 GLN B OE1 1 
ATOM   4259  N NE2 . GLN B 1 149 ? 104.640 123.149 126.488 1.00 49.89 ? 149 GLN B NE2 1 
ATOM   4260  N N   . LEU B 1 150 ? 101.159 118.908 127.676 1.00 49.84 ? 150 LEU B N   1 
ATOM   4261  C CA  . LEU B 1 150 ? 100.144 118.680 126.655 1.00 49.84 ? 150 LEU B CA  1 
ATOM   4262  C C   . LEU B 1 150 ? 98.809  119.268 127.076 1.00 49.84 ? 150 LEU B C   1 
ATOM   4263  O O   . LEU B 1 150 ? 98.188  120.021 126.321 1.00 49.84 ? 150 LEU B O   1 
ATOM   4264  C CB  . LEU B 1 150 ? 100.004 117.189 126.364 1.00 49.84 ? 150 LEU B CB  1 
ATOM   4265  C CG  . LEU B 1 150 ? 101.237 116.528 125.752 1.00 49.84 ? 150 LEU B CG  1 
ATOM   4266  C CD1 . LEU B 1 150 ? 100.932 115.118 125.291 1.00 49.84 ? 150 LEU B CD1 1 
ATOM   4267  C CD2 . LEU B 1 150 ? 101.771 117.370 124.610 1.00 49.84 ? 150 LEU B CD2 1 
ATOM   4268  N N   . GLN B 1 151 ? 98.351  118.941 128.283 1.00 54.37 ? 151 GLN B N   1 
ATOM   4269  C CA  . GLN B 1 151 ? 97.085  119.442 128.815 1.00 54.37 ? 151 GLN B CA  1 
ATOM   4270  C C   . GLN B 1 151 ? 97.378  120.279 130.051 1.00 54.37 ? 151 GLN B C   1 
ATOM   4271  O O   . GLN B 1 151 ? 97.396  119.749 131.171 1.00 54.37 ? 151 GLN B O   1 
ATOM   4272  C CB  . GLN B 1 151 ? 96.137  118.298 129.163 1.00 54.37 ? 151 GLN B CB  1 
ATOM   4273  C CG  . GLN B 1 151 ? 95.865  117.320 128.035 1.00 54.37 ? 151 GLN B CG  1 
ATOM   4274  C CD  . GLN B 1 151 ? 96.706  116.065 128.141 1.00 54.37 ? 151 GLN B CD  1 
ATOM   4275  O OE1 . GLN B 1 151 ? 97.384  115.848 129.140 1.00 54.37 ? 151 GLN B OE1 1 
ATOM   4276  N NE2 . GLN B 1 151 ? 96.650  115.224 127.118 1.00 54.37 ? 151 GLN B NE2 1 
ATOM   4277  N N   . PRO B 1 152 ? 97.617  121.580 129.904 1.00 58.16 ? 152 PRO B N   1 
ATOM   4278  C CA  . PRO B 1 152 ? 97.926  122.400 131.080 1.00 58.16 ? 152 PRO B CA  1 
ATOM   4279  C C   . PRO B 1 152 ? 96.746  122.462 132.034 1.00 58.16 ? 152 PRO B C   1 
ATOM   4280  O O   . PRO B 1 152 ? 95.585  122.457 131.620 1.00 58.16 ? 152 PRO B O   1 
ATOM   4281  C CB  . PRO B 1 152 ? 98.239  123.774 130.482 1.00 58.16 ? 152 PRO B CB  1 
ATOM   4282  C CG  . PRO B 1 152 ? 98.628  123.488 129.078 1.00 58.16 ? 152 PRO B CG  1 
ATOM   4283  C CD  . PRO B 1 152 ? 97.764  122.342 128.657 1.00 58.16 ? 152 PRO B CD  1 
ATOM   4284  N N   . GLY B 1 153 ? 97.059  122.503 133.326 1.00 57.98 ? 153 GLY B N   1 
ATOM   4285  C CA  . GLY B 1 153 ? 96.044  122.494 134.354 1.00 57.98 ? 153 GLY B CA  1 
ATOM   4286  C C   . GLY B 1 153 ? 95.380  121.158 134.588 1.00 57.98 ? 153 GLY B C   1 
ATOM   4287  O O   . GLY B 1 153 ? 94.466  121.077 135.417 1.00 57.98 ? 153 GLY B O   1 
ATOM   4288  N N   . GLY B 1 154 ? 95.809  120.110 133.897 1.00 60.89 ? 154 GLY B N   1 
ATOM   4289  C CA  . GLY B 1 154 ? 95.203  118.806 134.016 1.00 60.89 ? 154 GLY B CA  1 
ATOM   4290  C C   . GLY B 1 154 ? 95.918  117.821 134.906 1.00 60.89 ? 154 GLY B C   1 
ATOM   4291  O O   . GLY B 1 154 ? 95.450  116.688 135.044 1.00 60.89 ? 154 GLY B O   1 
ATOM   4292  N N   . VAL B 1 155 ? 97.039  118.200 135.513 1.00 59.65 ? 155 VAL B N   1 
ATOM   4293  C CA  . VAL B 1 155 ? 97.821  117.302 136.361 1.00 59.65 ? 155 VAL B CA  1 
ATOM   4294  C C   . VAL B 1 155 ? 98.088  118.036 137.672 1.00 59.65 ? 155 VAL B C   1 
ATOM   4295  O O   . VAL B 1 155 ? 99.062  118.784 137.797 1.00 59.65 ? 155 VAL B O   1 
ATOM   4296  C CB  . VAL B 1 155 ? 99.127  116.859 135.700 1.00 59.65 ? 155 VAL B CB  1 
ATOM   4297  C CG1 . VAL B 1 155 ? 99.904  115.962 136.630 1.00 59.65 ? 155 VAL B CG1 1 
ATOM   4298  C CG2 . VAL B 1 155 ? 98.832  116.143 134.405 1.00 59.65 ? 155 VAL B CG2 1 
ATOM   4299  N N   . ASP B 1 156 ? 97.229  117.820 138.662 1.00 60.31 ? 156 ASP B N   1 
ATOM   4300  C CA  . ASP B 1 156 ? 97.461  118.367 139.989 1.00 60.31 ? 156 ASP B CA  1 
ATOM   4301  C C   . ASP B 1 156 ? 98.449  117.487 140.737 1.00 60.31 ? 156 ASP B C   1 
ATOM   4302  O O   . ASP B 1 156 ? 98.334  116.260 140.737 1.00 60.31 ? 156 ASP B O   1 
ATOM   4303  C CB  . ASP B 1 156 ? 96.149  118.476 140.761 1.00 60.31 ? 156 ASP B CB  1 
ATOM   4304  C CG  . ASP B 1 156 ? 96.310  119.175 142.094 1.00 60.31 ? 156 ASP B CG  1 
ATOM   4305  O OD1 . ASP B 1 156 ? 97.412  119.676 142.381 1.00 60.31 ? 156 ASP B OD1 1 
ATOM   4306  O OD2 . ASP B 1 156 ? 95.328  119.226 142.859 1.00 60.31 ? 156 ASP B OD2 1 
ATOM   4307  N N   . SER B 1 157 ? 99.416  118.122 141.391 1.00 55.17 ? 157 SER B N   1 
ATOM   4308  C CA  . SER B 1 157 ? 100.565 117.421 141.943 1.00 55.17 ? 157 SER B CA  1 
ATOM   4309  C C   . SER B 1 157 ? 100.597 117.431 143.465 1.00 55.17 ? 157 SER B C   1 
ATOM   4310  O O   . SER B 1 157 ? 101.669 117.287 144.052 1.00 55.17 ? 157 SER B O   1 
ATOM   4311  C CB  . SER B 1 157 ? 101.850 118.029 141.390 1.00 55.17 ? 157 SER B CB  1 
ATOM   4312  O OG  . SER B 1 157 ? 102.986 117.326 141.852 1.00 55.17 ? 157 SER B OG  1 
ATOM   4313  N N   . THR B 1 158 ? 99.450  117.573 144.123 1.00 57.18 ? 158 THR B N   1 
ATOM   4314  C CA  . THR B 1 158 ? 99.449  117.668 145.578 1.00 57.18 ? 158 THR B CA  1 
ATOM   4315  C C   . THR B 1 158 ? 99.848  116.348 146.225 1.00 57.18 ? 158 THR B C   1 
ATOM   4316  O O   . THR B 1 158 ? 100.867 116.260 146.921 1.00 57.18 ? 158 THR B O   1 
ATOM   4317  C CB  . THR B 1 158 ? 98.074  118.100 146.068 1.00 57.18 ? 158 THR B CB  1 
ATOM   4318  O OG1 . THR B 1 158 ? 97.723  119.346 145.458 1.00 57.18 ? 158 THR B OG1 1 
ATOM   4319  C CG2 . THR B 1 158 ? 98.094  118.269 147.558 1.00 57.18 ? 158 THR B CG2 1 
ATOM   4320  N N   . MET B 1 159 ? 99.055  115.301 146.002 1.00 58.09 ? 159 MET B N   1 
ATOM   4321  C CA  . MET B 1 159 ? 99.292  114.047 146.705 1.00 58.09 ? 159 MET B CA  1 
ATOM   4322  C C   . MET B 1 159 ? 100.607 113.426 146.287 1.00 58.09 ? 159 MET B C   1 
ATOM   4323  O O   . MET B 1 159 ? 101.263 112.755 147.088 1.00 58.09 ? 159 MET B O   1 
ATOM   4324  C CB  . MET B 1 159 ? 98.151  113.072 146.455 1.00 58.09 ? 159 MET B CB  1 
ATOM   4325  C CG  . MET B 1 159 ? 96.796  113.648 146.721 1.00 58.09 ? 159 MET B CG  1 
ATOM   4326  S SD  . MET B 1 159 ? 95.555  112.371 146.601 1.00 58.09 ? 159 MET B SD  1 
ATOM   4327  C CE  . MET B 1 159 ? 95.852  111.515 148.133 1.00 58.09 ? 159 MET B CE  1 
ATOM   4328  N N   . PHE B 1 160 ? 100.995 113.611 145.028 1.00 51.67 ? 160 PHE B N   1 
ATOM   4329  C CA  . PHE B 1 160 ? 102.328 113.201 144.623 1.00 51.67 ? 160 PHE B CA  1 
ATOM   4330  C C   . PHE B 1 160 ? 103.367 113.879 145.491 1.00 51.67 ? 160 PHE B C   1 
ATOM   4331  O O   . PHE B 1 160 ? 104.305 113.234 145.971 1.00 51.67 ? 160 PHE B O   1 
ATOM   4332  C CB  . PHE B 1 160 ? 102.561 113.526 143.149 1.00 51.67 ? 160 PHE B CB  1 
ATOM   4333  C CG  . PHE B 1 160 ? 103.849 112.980 142.605 1.00 51.67 ? 160 PHE B CG  1 
ATOM   4334  C CD1 . PHE B 1 160 ? 105.047 113.615 142.852 1.00 51.67 ? 160 PHE B CD1 1 
ATOM   4335  C CD2 . PHE B 1 160 ? 103.859 111.833 141.848 1.00 51.67 ? 160 PHE B CD2 1 
ATOM   4336  C CE1 . PHE B 1 160 ? 106.222 113.114 142.361 1.00 51.67 ? 160 PHE B CE1 1 
ATOM   4337  C CE2 . PHE B 1 160 ? 105.039 111.331 141.353 1.00 51.67 ? 160 PHE B CE2 1 
ATOM   4338  C CZ  . PHE B 1 160 ? 106.218 111.972 141.612 1.00 51.67 ? 160 PHE B CZ  1 
ATOM   4339  N N   . ASP B 1 161 ? 103.196 115.178 145.730 1.00 57.32 ? 161 ASP B N   1 
ATOM   4340  C CA  . ASP B 1 161 ? 104.155 115.909 146.543 1.00 57.32 ? 161 ASP B CA  1 
ATOM   4341  C C   . ASP B 1 161 ? 104.190 115.372 147.962 1.00 57.32 ? 161 ASP B C   1 
ATOM   4342  O O   . ASP B 1 161 ? 105.260 115.273 148.568 1.00 57.32 ? 161 ASP B O   1 
ATOM   4343  C CB  . ASP B 1 161 ? 103.813 117.395 146.543 1.00 57.32 ? 161 ASP B CB  1 
ATOM   4344  C CG  . ASP B 1 161 ? 104.089 118.057 145.214 1.00 57.32 ? 161 ASP B CG  1 
ATOM   4345  O OD1 . ASP B 1 161 ? 104.827 117.477 144.393 1.00 57.32 ? 161 ASP B OD1 1 
ATOM   4346  O OD2 . ASP B 1 161 ? 103.555 119.160 144.982 1.00 57.32 ? 161 ASP B OD2 1 
ATOM   4347  N N   . HIS B 1 162 ? 103.030 115.007 148.507 1.00 57.33 ? 162 HIS B N   1 
ATOM   4348  C CA  . HIS B 1 162 ? 103.011 114.548 149.891 1.00 57.33 ? 162 HIS B CA  1 
ATOM   4349  C C   . HIS B 1 162 ? 103.607 113.156 150.036 1.00 57.33 ? 162 HIS B C   1 
ATOM   4350  O O   . HIS B 1 162 ? 104.290 112.873 151.025 1.00 57.33 ? 162 HIS B O   1 
ATOM   4351  C CB  . HIS B 1 162 ? 101.597 114.553 150.452 1.00 57.33 ? 162 HIS B CB  1 
ATOM   4352  C CG  . HIS B 1 162 ? 101.529 114.064 151.863 1.00 57.33 ? 162 HIS B CG  1 
ATOM   4353  N ND1 . HIS B 1 162 ? 101.659 114.903 152.946 1.00 57.33 ? 162 HIS B ND1 1 
ATOM   4354  C CD2 . HIS B 1 162 ? 101.394 112.817 152.368 1.00 57.33 ? 162 HIS B CD2 1 
ATOM   4355  C CE1 . HIS B 1 162 ? 101.584 114.197 154.059 1.00 57.33 ? 162 HIS B CE1 1 
ATOM   4356  N NE2 . HIS B 1 162 ? 101.425 112.928 153.736 1.00 57.33 ? 162 HIS B NE2 1 
ATOM   4357  N N   . PHE B 1 163 ? 103.346 112.266 149.079 1.00 54.06 ? 163 PHE B N   1 
ATOM   4358  C CA  . PHE B 1 163 ? 103.677 110.856 149.248 1.00 54.06 ? 163 PHE B CA  1 
ATOM   4359  C C   . PHE B 1 163 ? 105.015 110.458 148.659 1.00 54.06 ? 163 PHE B C   1 
ATOM   4360  O O   . PHE B 1 163 ? 105.599 109.478 149.123 1.00 54.06 ? 163 PHE B O   1 
ATOM   4361  C CB  . PHE B 1 163 ? 102.600 109.979 148.625 1.00 54.06 ? 163 PHE B CB  1 
ATOM   4362  C CG  . PHE B 1 163 ? 101.397 109.828 149.476 1.00 54.06 ? 163 PHE B CG  1 
ATOM   4363  C CD1 . PHE B 1 163 ? 101.450 109.092 150.634 1.00 54.06 ? 163 PHE B CD1 1 
ATOM   4364  C CD2 . PHE B 1 163 ? 100.212 110.427 149.125 1.00 54.06 ? 163 PHE B CD2 1 
ATOM   4365  C CE1 . PHE B 1 163 ? 100.343 108.955 151.423 1.00 54.06 ? 163 PHE B CE1 1 
ATOM   4366  C CE2 . PHE B 1 163 ? 99.102  110.289 149.914 1.00 54.06 ? 163 PHE B CE2 1 
ATOM   4367  C CZ  . PHE B 1 163 ? 99.169  109.554 151.063 1.00 54.06 ? 163 PHE B CZ  1 
ATOM   4368  N N   . TYR B 1 164 ? 105.507 111.160 147.647 1.00 52.83 ? 164 TYR B N   1 
ATOM   4369  C CA  . TYR B 1 164 ? 106.842 110.870 147.143 1.00 52.83 ? 164 TYR B CA  1 
ATOM   4370  C C   . TYR B 1 164 ? 107.906 110.834 148.232 1.00 52.83 ? 164 TYR B C   1 
ATOM   4371  O O   . TYR B 1 164 ? 108.839 110.025 148.111 1.00 52.83 ? 164 TYR B O   1 
ATOM   4372  C CB  . TYR B 1 164 ? 107.206 111.893 146.059 1.00 52.83 ? 164 TYR B CB  1 
ATOM   4373  C CG  . TYR B 1 164 ? 108.499 111.598 145.342 1.00 52.83 ? 164 TYR B CG  1 
ATOM   4374  C CD1 . TYR B 1 164 ? 108.539 110.713 144.285 1.00 52.83 ? 164 TYR B CD1 1 
ATOM   4375  C CD2 . TYR B 1 164 ? 109.677 112.210 145.723 1.00 52.83 ? 164 TYR B CD2 1 
ATOM   4376  C CE1 . TYR B 1 164 ? 109.715 110.441 143.630 1.00 52.83 ? 164 TYR B CE1 1 
ATOM   4377  C CE2 . TYR B 1 164 ? 110.855 111.945 145.071 1.00 52.83 ? 164 TYR B CE2 1 
ATOM   4378  C CZ  . TYR B 1 164 ? 110.868 111.059 144.026 1.00 52.83 ? 164 TYR B CZ  1 
ATOM   4379  O OH  . TYR B 1 164 ? 112.043 110.789 143.370 1.00 52.83 ? 164 TYR B OH  1 
ATOM   4380  N N   . PRO B 1 165 ? 107.854 111.653 149.288 1.00 52.92 ? 165 PRO B N   1 
ATOM   4381  C CA  . PRO B 1 165 ? 108.870 111.507 150.341 1.00 52.92 ? 165 PRO B CA  1 
ATOM   4382  C C   . PRO B 1 165 ? 108.685 110.274 151.203 1.00 52.92 ? 165 PRO B C   1 
ATOM   4383  O O   . PRO B 1 165 ? 109.669 109.604 151.537 1.00 52.92 ? 165 PRO B O   1 
ATOM   4384  C CB  . PRO B 1 165 ? 108.702 112.792 151.158 1.00 52.92 ? 165 PRO B CB  1 
ATOM   4385  C CG  . PRO B 1 165 ? 108.002 113.721 150.274 1.00 52.92 ? 165 PRO B CG  1 
ATOM   4386  C CD  . PRO B 1 165 ? 107.098 112.903 149.458 1.00 52.92 ? 165 PRO B CD  1 
ATOM   4387  N N   . LEU B 1 166 ? 107.450 109.950 151.573 1.00 54.05 ? 166 LEU B N   1 
ATOM   4388  C CA  . LEU B 1 166 ? 107.217 108.910 152.565 1.00 54.05 ? 166 LEU B CA  1 
ATOM   4389  C C   . LEU B 1 166 ? 107.250 107.519 151.949 1.00 54.05 ? 166 LEU B C   1 
ATOM   4390  O O   . LEU B 1 166 ? 107.856 106.603 152.509 1.00 54.05 ? 166 LEU B O   1 
ATOM   4391  C CB  . LEU B 1 166 ? 105.884 109.155 153.257 1.00 54.05 ? 166 LEU B CB  1 
ATOM   4392  C CG  . LEU B 1 166 ? 105.682 110.622 153.615 1.00 54.05 ? 166 LEU B CG  1 
ATOM   4393  C CD1 . LEU B 1 166 ? 104.295 110.865 154.151 1.00 54.05 ? 166 LEU B CD1 1 
ATOM   4394  C CD2 . LEU B 1 166 ? 106.722 111.042 154.623 1.00 54.05 ? 166 LEU B CD2 1 
ATOM   4395  N N   . LEU B 1 167 ? 106.602 107.339 150.802 1.00 56.35 ? 167 LEU B N   1 
ATOM   4396  C CA  . LEU B 1 167 ? 106.507 106.018 150.194 1.00 56.35 ? 167 LEU B CA  1 
ATOM   4397  C C   . LEU B 1 167 ? 107.656 105.715 149.248 1.00 56.35 ? 167 LEU B C   1 
ATOM   4398  O O   . LEU B 1 167 ? 108.307 104.678 149.380 1.00 56.35 ? 167 LEU B O   1 
ATOM   4399  C CB  . LEU B 1 167 ? 105.198 105.884 149.425 1.00 56.35 ? 167 LEU B CB  1 
ATOM   4400  C CG  . LEU B 1 167 ? 103.913 105.898 150.234 1.00 56.35 ? 167 LEU B CG  1 
ATOM   4401  C CD1 . LEU B 1 167 ? 102.748 105.796 149.292 1.00 56.35 ? 167 LEU B CD1 1 
ATOM   4402  C CD2 . LEU B 1 167 ? 103.900 104.762 151.222 1.00 56.35 ? 167 LEU B CD2 1 
ATOM   4403  N N   . CYS B 1 168 ? 107.910 106.589 148.288 1.00 56.76 ? 168 CYS B N   1 
ATOM   4404  C CA  . CYS B 1 168 ? 108.848 106.288 147.227 1.00 56.76 ? 168 CYS B CA  1 
ATOM   4405  C C   . CYS B 1 168 ? 110.274 106.521 147.697 1.00 56.76 ? 168 CYS B C   1 
ATOM   4406  O O   . CYS B 1 168 ? 110.531 106.889 148.843 1.00 56.76 ? 168 CYS B O   1 
ATOM   4407  C CB  . CYS B 1 168 ? 108.541 107.127 145.993 1.00 56.76 ? 168 CYS B CB  1 
ATOM   4408  S SG  . CYS B 1 168 ? 109.635 106.814 144.606 1.00 56.76 ? 168 CYS B SG  1 
ATOM   4409  N N   . VAL B 1 169 ? 111.217 106.295 146.793 1.00 58.24 ? 169 VAL B N   1 
ATOM   4410  C CA  . VAL B 1 169 ? 112.626 106.549 147.040 1.00 58.24 ? 169 VAL B CA  1 
ATOM   4411  C C   . VAL B 1 169 ? 113.198 107.242 145.818 1.00 58.24 ? 169 VAL B C   1 
ATOM   4412  O O   . VAL B 1 169 ? 113.100 106.719 144.704 1.00 58.24 ? 169 VAL B O   1 
ATOM   4413  C CB  . VAL B 1 169 ? 113.402 105.256 147.328 1.00 58.24 ? 169 VAL B CB  1 
ATOM   4414  C CG1 . VAL B 1 169 ? 114.878 105.527 147.258 1.00 58.24 ? 169 VAL B CG1 1 
ATOM   4415  C CG2 . VAL B 1 169 ? 113.037 104.719 148.686 1.00 58.24 ? 169 VAL B CG2 1 
ATOM   4416  N N   . ASP B 1 170 ? 113.794 108.409 146.024 1.00 60.69 ? 170 ASP B N   1 
ATOM   4417  C CA  . ASP B 1 170 ? 114.391 109.149 144.928 1.00 60.69 ? 170 ASP B CA  1 
ATOM   4418  C C   . ASP B 1 170 ? 115.678 108.471 144.480 1.00 60.69 ? 170 ASP B C   1 
ATOM   4419  O O   . ASP B 1 170 ? 116.111 107.461 145.035 1.00 60.69 ? 170 ASP B O   1 
ATOM   4420  C CB  . ASP B 1 170 ? 114.649 110.593 145.341 1.00 60.69 ? 170 ASP B CB  1 
ATOM   4421  C CG  . ASP B 1 170 ? 115.382 110.688 146.657 1.00 60.69 ? 170 ASP B CG  1 
ATOM   4422  O OD1 . ASP B 1 170 ? 115.473 109.653 147.340 1.00 60.69 ? 170 ASP B OD1 1 
ATOM   4423  O OD2 . ASP B 1 170 ? 115.872 111.783 147.005 1.00 60.69 ? 170 ASP B OD2 1 
ATOM   4424  N N   . GLY B 1 171 ? 116.299 109.041 143.459 1.00 58.78 ? 171 GLY B N   1 
ATOM   4425  C CA  . GLY B 1 171 ? 117.536 108.529 142.931 1.00 58.78 ? 171 GLY B CA  1 
ATOM   4426  C C   . GLY B 1 171 ? 118.657 108.469 143.944 1.00 58.78 ? 171 GLY B C   1 
ATOM   4427  O O   . GLY B 1 171 ? 119.255 107.413 144.164 1.00 58.78 ? 171 GLY B O   1 
ATOM   4428  N N   . PRO B 1 172 ? 118.978 109.603 144.576 1.00 59.38 ? 172 PRO B N   1 
ATOM   4429  C CA  . PRO B 1 172 ? 120.140 109.613 145.479 1.00 59.38 ? 172 PRO B CA  1 
ATOM   4430  C C   . PRO B 1 172 ? 119.995 108.703 146.683 1.00 59.38 ? 172 PRO B C   1 
ATOM   4431  O O   . PRO B 1 172 ? 120.954 108.012 147.044 1.00 59.38 ? 172 PRO B O   1 
ATOM   4432  C CB  . PRO B 1 172 ? 120.243 111.088 145.884 1.00 59.38 ? 172 PRO B CB  1 
ATOM   4433  C CG  . PRO B 1 172 ? 119.610 111.815 144.773 1.00 59.38 ? 172 PRO B CG  1 
ATOM   4434  C CD  . PRO B 1 172 ? 118.466 110.964 144.353 1.00 59.38 ? 172 PRO B CD  1 
ATOM   4435  N N   . GLU B 1 173 ? 118.828 108.683 147.324 1.00 61.75 ? 173 GLU B N   1 
ATOM   4436  C CA  . GLU B 1 173 ? 118.642 107.799 148.468 1.00 61.75 ? 173 GLU B CA  1 
ATOM   4437  C C   . GLU B 1 173 ? 118.809 106.345 148.067 1.00 61.75 ? 173 GLU B C   1 
ATOM   4438  O O   . GLU B 1 173 ? 119.454 105.567 148.777 1.00 61.75 ? 173 GLU B O   1 
ATOM   4439  C CB  . GLU B 1 173 ? 117.267 108.026 149.081 1.00 61.75 ? 173 GLU B CB  1 
ATOM   4440  C CG  . GLU B 1 173 ? 116.963 107.172 150.279 1.00 61.75 ? 173 GLU B CG  1 
ATOM   4441  C CD  . GLU B 1 173 ? 115.651 107.555 150.914 1.00 61.75 ? 173 GLU B CD  1 
ATOM   4442  O OE1 . GLU B 1 173 ? 114.837 108.210 150.230 1.00 61.75 ? 173 GLU B OE1 1 
ATOM   4443  O OE2 . GLU B 1 173 ? 115.433 107.211 152.092 1.00 61.75 ? 173 GLU B OE2 1 
ATOM   4444  N N   . ALA B 1 174 ? 118.234 105.959 146.928 1.00 58.50 ? 174 ALA B N   1 
ATOM   4445  C CA  . ALA B 1 174 ? 118.387 104.591 146.457 1.00 58.50 ? 174 ALA B CA  1 
ATOM   4446  C C   . ALA B 1 174 ? 119.832 104.278 146.118 1.00 58.50 ? 174 ALA B C   1 
ATOM   4447  O O   . ALA B 1 174 ? 120.276 103.141 146.295 1.00 58.50 ? 174 ALA B O   1 
ATOM   4448  C CB  . ALA B 1 174 ? 117.496 104.351 145.244 1.00 58.50 ? 174 ALA B CB  1 
ATOM   4449  N N   . ARG B 1 175 ? 120.584 105.263 145.638 1.00 57.78 ? 175 ARG B N   1 
ATOM   4450  C CA  . ARG B 1 175 ? 121.969 104.996 145.282 1.00 57.78 ? 175 ARG B CA  1 
ATOM   4451  C C   . ARG B 1 175 ? 122.870 104.908 146.503 1.00 57.78 ? 175 ARG B C   1 
ATOM   4452  O O   . ARG B 1 175 ? 123.853 104.160 146.484 1.00 57.78 ? 175 ARG B O   1 
ATOM   4453  C CB  . ARG B 1 175 ? 122.482 106.066 144.323 1.00 57.78 ? 175 ARG B CB  1 
ATOM   4454  C CG  . ARG B 1 175 ? 121.922 105.942 142.924 1.00 57.78 ? 175 ARG B CG  1 
ATOM   4455  C CD  . ARG B 1 175 ? 122.798 106.635 141.901 1.00 57.78 ? 175 ARG B CD  1 
ATOM   4456  N NE  . ARG B 1 175 ? 122.769 108.086 142.041 1.00 57.78 ? 175 ARG B NE  1 
ATOM   4457  C CZ  . ARG B 1 175 ? 121.756 108.860 141.666 1.00 57.78 ? 175 ARG B CZ  1 
ATOM   4458  N NH1 . ARG B 1 175 ? 120.671 108.328 141.126 1.00 57.78 ? 175 ARG B NH1 1 
ATOM   4459  N NH2 . ARG B 1 175 ? 121.831 110.170 141.833 1.00 57.78 ? 175 ARG B NH2 1 
ATOM   4460  N N   . ARG B 1 176 ? 122.565 105.650 147.569 1.00 63.30 ? 176 ARG B N   1 
ATOM   4461  C CA  . ARG B 1 176 ? 123.395 105.570 148.769 1.00 63.30 ? 176 ARG B CA  1 
ATOM   4462  C C   . ARG B 1 176 ? 123.240 104.223 149.458 1.00 63.30 ? 176 ARG B C   1 
ATOM   4463  O O   . ARG B 1 176 ? 124.212 103.666 149.976 1.00 63.30 ? 176 ARG B O   1 
ATOM   4464  C CB  . ARG B 1 176 ? 123.044 106.698 149.739 1.00 63.30 ? 176 ARG B CB  1 
ATOM   4465  C CG  . ARG B 1 176 ? 123.336 108.089 149.216 1.00 63.30 ? 176 ARG B CG  1 
ATOM   4466  C CD  . ARG B 1 176 ? 123.150 109.147 150.287 1.00 63.30 ? 176 ARG B CD  1 
ATOM   4467  N NE  . ARG B 1 176 ? 121.920 108.964 151.051 1.00 63.30 ? 176 ARG B NE  1 
ATOM   4468  C CZ  . ARG B 1 176 ? 120.799 109.646 150.845 1.00 63.30 ? 176 ARG B CZ  1 
ATOM   4469  N NH1 . ARG B 1 176 ? 120.744 110.560 149.893 1.00 63.30 ? 176 ARG B NH1 1 
ATOM   4470  N NH2 . ARG B 1 176 ? 119.731 109.415 151.594 1.00 63.30 ? 176 ARG B NH2 1 
ATOM   4471  N N   . GLN B 1 177 ? 122.027 103.688 149.470 1.00 64.18 ? 177 GLN B N   1 
ATOM   4472  C CA  . GLN B 1 177 ? 121.692 102.465 150.186 1.00 64.18 ? 177 GLN B CA  1 
ATOM   4473  C C   . GLN B 1 177 ? 121.525 101.283 149.239 1.00 64.18 ? 177 GLN B C   1 
ATOM   4474  O O   . GLN B 1 177 ? 120.601 100.485 149.383 1.00 64.18 ? 177 GLN B O   1 
ATOM   4475  C CB  . GLN B 1 177 ? 120.431 102.667 151.018 1.00 64.18 ? 177 GLN B CB  1 
ATOM   4476  C CG  . GLN B 1 177 ? 120.667 103.444 152.297 1.00 64.18 ? 177 GLN B CG  1 
ATOM   4477  C CD  . GLN B 1 177 ? 119.411 104.098 152.819 1.00 64.18 ? 177 GLN B CD  1 
ATOM   4478  O OE1 . GLN B 1 177 ? 118.407 104.181 152.118 1.00 64.18 ? 177 GLN B OE1 1 
ATOM   4479  N NE2 . GLN B 1 177 ? 119.460 104.572 154.055 1.00 64.18 ? 177 GLN B NE2 1 
ATOM   4480  N N   . TRP B 1 178 ? 122.402 101.168 148.240 1.00 62.87 ? 178 TRP B N   1 
ATOM   4481  C CA  . TRP B 1 178 ? 122.211 100.132 147.233 1.00 62.87 ? 178 TRP B CA  1 
ATOM   4482  C C   . TRP B 1 178 ? 122.423 98.736  147.791 1.00 62.87 ? 178 TRP B C   1 
ATOM   4483  O O   . TRP B 1 178 ? 121.857 97.771  147.269 1.00 62.87 ? 178 TRP B O   1 
ATOM   4484  C CB  . TRP B 1 178 ? 123.141 100.340 146.049 1.00 62.87 ? 178 TRP B CB  1 
ATOM   4485  C CG  . TRP B 1 178 ? 122.749 99.465  144.923 1.00 62.87 ? 178 TRP B CG  1 
ATOM   4486  C CD1 . TRP B 1 178 ? 123.444 98.411  144.425 1.00 62.87 ? 178 TRP B CD1 1 
ATOM   4487  C CD2 . TRP B 1 178 ? 121.534 99.538  144.174 1.00 62.87 ? 178 TRP B CD2 1 
ATOM   4488  N NE1 . TRP B 1 178 ? 122.747 97.833  143.394 1.00 62.87 ? 178 TRP B NE1 1 
ATOM   4489  C CE2 . TRP B 1 178 ? 121.570 98.510  143.221 1.00 62.87 ? 178 TRP B CE2 1 
ATOM   4490  C CE3 . TRP B 1 178 ? 120.426 100.381 144.209 1.00 62.87 ? 178 TRP B CE3 1 
ATOM   4491  C CZ2 . TRP B 1 178 ? 120.541 98.303  142.313 1.00 62.87 ? 178 TRP B CZ2 1 
ATOM   4492  C CZ3 . TRP B 1 178 ? 119.410 100.174 143.308 1.00 62.87 ? 178 TRP B CZ3 1 
ATOM   4493  C CH2 . TRP B 1 178 ? 119.473 99.148  142.373 1.00 62.87 ? 178 TRP B CH2 1 
ATOM   4494  N N   . ASP B 1 179 ? 123.245 98.601  148.826 1.00 66.88 ? 179 ASP B N   1 
ATOM   4495  C CA  . ASP B 1 179 ? 123.418 97.300  149.451 1.00 66.88 ? 179 ASP B CA  1 
ATOM   4496  C C   . ASP B 1 179 ? 122.104 96.751  149.981 1.00 66.88 ? 179 ASP B C   1 
ATOM   4497  O O   . ASP B 1 179 ? 121.929 95.532  150.067 1.00 66.88 ? 179 ASP B O   1 
ATOM   4498  C CB  . ASP B 1 179 ? 124.439 97.411  150.574 1.00 66.88 ? 179 ASP B CB  1 
ATOM   4499  C CG  . ASP B 1 179 ? 124.055 98.454  151.602 1.00 66.88 ? 179 ASP B CG  1 
ATOM   4500  O OD1 . ASP B 1 179 ? 123.033 99.143  151.404 1.00 66.88 ? 179 ASP B OD1 1 
ATOM   4501  O OD2 . ASP B 1 179 ? 124.777 98.589  152.611 1.00 66.88 ? 179 ASP B OD2 1 
ATOM   4502  N N   . SER B 1 180 ? 121.167 97.629  150.330 1.00 63.18 ? 180 SER B N   1 
ATOM   4503  C CA  . SER B 1 180 ? 119.966 97.185  151.024 1.00 63.18 ? 180 SER B CA  1 
ATOM   4504  C C   . SER B 1 180 ? 118.950 96.579  150.067 1.00 63.18 ? 180 SER B C   1 
ATOM   4505  O O   . SER B 1 180 ? 118.255 95.624  150.422 1.00 63.18 ? 180 SER B O   1 
ATOM   4506  C CB  . SER B 1 180 ? 119.353 98.354  151.787 1.00 63.18 ? 180 SER B CB  1 
ATOM   4507  O OG  . SER B 1 180 ? 117.982 98.138  152.035 1.00 63.18 ? 180 SER B OG  1 
ATOM   4508  N N   . ILE B 1 181 ? 118.844 97.112  148.854 1.00 64.73 ? 181 ILE B N   1 
ATOM   4509  C CA  . ILE B 1 181 ? 117.773 96.737  147.941 1.00 64.73 ? 181 ILE B CA  1 
ATOM   4510  C C   . ILE B 1 181 ? 118.294 96.022  146.704 1.00 64.73 ? 181 ILE B C   1 
ATOM   4511  O O   . ILE B 1 181 ? 117.527 95.775  145.772 1.00 64.73 ? 181 ILE B O   1 
ATOM   4512  C CB  . ILE B 1 181 ? 116.938 97.958  147.542 1.00 64.73 ? 181 ILE B CB  1 
ATOM   4513  C CG1 . ILE B 1 181 ? 117.852 99.057  147.010 1.00 64.73 ? 181 ILE B CG1 1 
ATOM   4514  C CG2 . ILE B 1 181 ? 116.153 98.455  148.722 1.00 64.73 ? 181 ILE B CG2 1 
ATOM   4515  C CD1 . ILE B 1 181 ? 117.116 100.196 146.360 1.00 64.73 ? 181 ILE B CD1 1 
ATOM   4516  N N   . ALA B 1 182 ? 119.580 95.680  146.668 1.00 65.71 ? 182 ALA B N   1 
ATOM   4517  C CA  . ALA B 1 182 ? 120.120 95.026  145.484 1.00 65.71 ? 182 ALA B CA  1 
ATOM   4518  C C   . ALA B 1 182 ? 119.531 93.634  145.304 1.00 65.71 ? 182 ALA B C   1 
ATOM   4519  O O   . ALA B 1 182 ? 119.278 93.204  144.174 1.00 65.71 ? 182 ALA B O   1 
ATOM   4520  C CB  . ALA B 1 182 ? 121.642 94.961  145.567 1.00 65.71 ? 182 ALA B CB  1 
ATOM   4521  N N   . HIS B 1 183 ? 119.296 92.919  146.403 1.00 65.89 ? 183 HIS B N   1 
ATOM   4522  C CA  . HIS B 1 183 ? 118.763 91.566  146.310 1.00 65.89 ? 183 HIS B CA  1 
ATOM   4523  C C   . HIS B 1 183 ? 117.350 91.526  145.748 1.00 65.89 ? 183 HIS B C   1 
ATOM   4524  O O   . HIS B 1 183 ? 116.892 90.453  145.345 1.00 65.89 ? 183 HIS B O   1 
ATOM   4525  C CB  . HIS B 1 183 ? 118.773 90.907  147.682 1.00 65.89 ? 183 HIS B CB  1 
ATOM   4526  C CG  . HIS B 1 183 ? 117.705 91.419  148.589 1.00 65.89 ? 183 HIS B CG  1 
ATOM   4527  N ND1 . HIS B 1 183 ? 117.920 92.446  149.480 1.00 65.89 ? 183 HIS B ND1 1 
ATOM   4528  C CD2 . HIS B 1 183 ? 116.408 91.065  148.727 1.00 65.89 ? 183 HIS B CD2 1 
ATOM   4529  C CE1 . HIS B 1 183 ? 116.803 92.695  150.137 1.00 65.89 ? 183 HIS B CE1 1 
ATOM   4530  N NE2 . HIS B 1 183 ? 115.869 91.873  149.697 1.00 65.89 ? 183 HIS B NE2 1 
ATOM   4531  N N   . ILE B 1 184 ? 116.637 92.651  145.733 1.00 62.09 ? 184 ILE B N   1 
ATOM   4532  C CA  . ILE B 1 184 ? 115.286 92.655  145.193 1.00 62.09 ? 184 ILE B CA  1 
ATOM   4533  C C   . ILE B 1 184 ? 115.343 92.410  143.695 1.00 62.09 ? 184 ILE B C   1 
ATOM   4534  O O   . ILE B 1 184 ? 116.223 92.926  142.995 1.00 62.09 ? 184 ILE B O   1 
ATOM   4535  C CB  . ILE B 1 184 ? 114.573 93.977  145.510 1.00 62.09 ? 184 ILE B CB  1 
ATOM   4536  C CG1 . ILE B 1 184 ? 114.471 94.163  147.017 1.00 62.09 ? 184 ILE B CG1 1 
ATOM   4537  C CG2 . ILE B 1 184 ? 113.188 93.997  144.903 1.00 62.09 ? 184 ILE B CG2 1 
ATOM   4538  C CD1 . ILE B 1 184 ? 113.637 95.345  147.413 1.00 62.09 ? 184 ILE B CD1 1 
ATOM   4539  N N   . TYR B 1 185 ? 114.407 91.604  143.197 1.00 58.54 ? 185 TYR B N   1 
ATOM   4540  C CA  . TYR B 1 185 ? 114.378 91.307  141.773 1.00 58.54 ? 185 TYR B CA  1 
ATOM   4541  C C   . TYR B 1 185 ? 113.714 92.426  140.984 1.00 58.54 ? 185 TYR B C   1 
ATOM   4542  O O   . TYR B 1 185 ? 114.295 92.951  140.029 1.00 58.54 ? 185 TYR B O   1 
ATOM   4543  C CB  . TYR B 1 185 ? 113.658 89.988  141.522 1.00 58.54 ? 185 TYR B CB  1 
ATOM   4544  C CG  . TYR B 1 185 ? 113.726 89.570  140.080 1.00 58.54 ? 185 TYR B CG  1 
ATOM   4545  C CD1 . TYR B 1 185 ? 114.948 89.358  139.463 1.00 58.54 ? 185 TYR B CD1 1 
ATOM   4546  C CD2 . TYR B 1 185 ? 112.574 89.407  139.330 1.00 58.54 ? 185 TYR B CD2 1 
ATOM   4547  C CE1 . TYR B 1 185 ? 115.021 88.987  138.147 1.00 58.54 ? 185 TYR B CE1 1 
ATOM   4548  C CE2 . TYR B 1 185 ? 112.638 89.035  138.012 1.00 58.54 ? 185 TYR B CE2 1 
ATOM   4549  C CZ  . TYR B 1 185 ? 113.864 88.826  137.425 1.00 58.54 ? 185 TYR B CZ  1 
ATOM   4550  O OH  . TYR B 1 185 ? 113.935 88.452  136.105 1.00 58.54 ? 185 TYR B OH  1 
ATOM   4551  N N   . HIS B 1 186 ? 112.503 92.804  141.365 1.00 57.62 ? 186 HIS B N   1 
ATOM   4552  C CA  . HIS B 1 186 ? 111.766 93.855  140.682 1.00 57.62 ? 186 HIS B CA  1 
ATOM   4553  C C   . HIS B 1 186 ? 111.849 95.127  141.515 1.00 57.62 ? 186 HIS B C   1 
ATOM   4554  O O   . HIS B 1 186 ? 111.212 95.231  142.566 1.00 57.62 ? 186 HIS B O   1 
ATOM   4555  C CB  . HIS B 1 186 ? 110.320 93.437  140.460 1.00 57.62 ? 186 HIS B CB  1 
ATOM   4556  C CG  . HIS B 1 186 ? 109.610 94.264  139.444 1.00 57.62 ? 186 HIS B CG  1 
ATOM   4557  N ND1 . HIS B 1 186 ? 108.237 94.335  139.370 1.00 57.62 ? 186 HIS B ND1 1 
ATOM   4558  C CD2 . HIS B 1 186 ? 110.082 95.060  138.458 1.00 57.62 ? 186 HIS B CD2 1 
ATOM   4559  C CE1 . HIS B 1 186 ? 107.894 95.137  138.380 1.00 57.62 ? 186 HIS B CE1 1 
ATOM   4560  N NE2 . HIS B 1 186 ? 108.995 95.590  137.810 1.00 57.62 ? 186 HIS B NE2 1 
ATOM   4561  N N   . LYS B 1 187 ? 112.637 96.092  141.047 1.00 56.89 ? 187 LYS B N   1 
ATOM   4562  C CA  . LYS B 1 187 ? 112.801 97.367  141.742 1.00 56.89 ? 187 LYS B CA  1 
ATOM   4563  C C   . LYS B 1 187 ? 111.834 98.410  141.184 1.00 56.89 ? 187 LYS B C   1 
ATOM   4564  O O   . LYS B 1 187 ? 112.215 99.478  140.720 1.00 56.89 ? 187 LYS B O   1 
ATOM   4565  C CB  . LYS B 1 187 ? 114.243 97.838  141.637 1.00 56.89 ? 187 LYS B CB  1 
ATOM   4566  C CG  . LYS B 1 187 ? 115.231 96.793  142.056 1.00 56.89 ? 187 LYS B CG  1 
ATOM   4567  C CD  . LYS B 1 187 ? 116.644 97.266  141.873 1.00 56.89 ? 187 LYS B CD  1 
ATOM   4568  C CE  . LYS B 1 187 ? 117.637 96.199  142.306 1.00 56.89 ? 187 LYS B CE  1 
ATOM   4569  N NZ  . LYS B 1 187 ? 118.135 95.371  141.173 1.00 56.89 ? 187 LYS B NZ  1 
ATOM   4570  N N   . CYS B 1 188 ? 110.554 98.074  141.244 1.00 53.54 ? 188 CYS B N   1 
ATOM   4571  C CA  . CYS B 1 188 ? 109.500 98.955  140.775 1.00 53.54 ? 188 CYS B CA  1 
ATOM   4572  C C   . CYS B 1 188 ? 109.055 99.865  141.908 1.00 53.54 ? 188 CYS B C   1 
ATOM   4573  O O   . CYS B 1 188 ? 108.773 99.394  143.012 1.00 53.54 ? 188 CYS B O   1 
ATOM   4574  C CB  . CYS B 1 188 ? 108.322 98.137  140.259 1.00 53.54 ? 188 CYS B CB  1 
ATOM   4575  S SG  . CYS B 1 188 ? 106.833 99.077  139.991 1.00 53.54 ? 188 CYS B SG  1 
ATOM   4576  N N   . HIS B 1 189 ? 108.996 101.164 141.638 1.00 51.93 ? 189 HIS B N   1 
ATOM   4577  C CA  . HIS B 1 189 ? 108.610 102.133 142.652 1.00 51.93 ? 189 HIS B CA  1 
ATOM   4578  C C   . HIS B 1 189 ? 107.509 103.082 142.224 1.00 51.93 ? 189 HIS B C   1 
ATOM   4579  O O   . HIS B 1 189 ? 106.926 103.740 143.090 1.00 51.93 ? 189 HIS B O   1 
ATOM   4580  C CB  . HIS B 1 189 ? 109.824 102.962 143.098 1.00 51.93 ? 189 HIS B CB  1 
ATOM   4581  C CG  . HIS B 1 189 ? 110.619 103.540 141.970 1.00 51.93 ? 189 HIS B CG  1 
ATOM   4582  N ND1 . HIS B 1 189 ? 110.112 104.488 141.109 1.00 51.93 ? 189 HIS B ND1 1 
ATOM   4583  C CD2 . HIS B 1 189 ? 111.892 103.316 141.573 1.00 51.93 ? 189 HIS B CD2 1 
ATOM   4584  C CE1 . HIS B 1 189 ? 111.036 104.818 140.226 1.00 51.93 ? 189 HIS B CE1 1 
ATOM   4585  N NE2 . HIS B 1 189 ? 112.125 104.120 140.485 1.00 51.93 ? 189 HIS B NE2 1 
ATOM   4586  N N   . THR B 1 190 ? 107.200 103.179 140.938 1.00 50.33 ? 190 THR B N   1 
ATOM   4587  C CA  . THR B 1 190 ? 106.187 104.110 140.463 1.00 50.33 ? 190 THR B CA  1 
ATOM   4588  C C   . THR B 1 190 ? 105.514 103.475 139.261 1.00 50.33 ? 190 THR B C   1 
ATOM   4589  O O   . THR B 1 190 ? 106.188 103.159 138.280 1.00 50.33 ? 190 THR B O   1 
ATOM   4590  C CB  . THR B 1 190 ? 106.809 105.448 140.071 1.00 50.33 ? 190 THR B CB  1 
ATOM   4591  O OG1 . THR B 1 190 ? 107.581 105.957 141.160 1.00 50.33 ? 190 THR B OG1 1 
ATOM   4592  C CG2 . THR B 1 190 ? 105.726 106.447 139.734 1.00 50.33 ? 190 THR B CG2 1 
ATOM   4593  N N   . VAL B 1 191 ? 104.204 103.282 139.330 1.00 47.65 ? 191 VAL B N   1 
ATOM   4594  C CA  . VAL B 1 191 ? 103.452 102.716 138.218 1.00 47.65 ? 191 VAL B CA  1 
ATOM   4595  C C   . VAL B 1 191 ? 102.400 103.725 137.800 1.00 47.65 ? 191 VAL B C   1 
ATOM   4596  O O   . VAL B 1 191 ? 101.670 104.245 138.648 1.00 47.65 ? 191 VAL B O   1 
ATOM   4597  C CB  . VAL B 1 191 ? 102.801 101.377 138.594 1.00 47.65 ? 191 VAL B CB  1 
ATOM   4598  C CG1 . VAL B 1 191 ? 102.329 100.672 137.365 1.00 47.65 ? 191 VAL B CG1 1 
ATOM   4599  C CG2 . VAL B 1 191 ? 103.776 100.522 139.335 1.00 47.65 ? 191 VAL B CG2 1 
ATOM   4600  N N   . THR B 1 192 ? 102.316 104.007 136.503 1.00 44.68 ? 192 THR B N   1 
ATOM   4601  C CA  . THR B 1 192 ? 101.427 105.046 136.010 1.00 44.68 ? 192 THR B CA  1 
ATOM   4602  C C   . THR B 1 192 ? 100.370 104.438 135.111 1.00 44.68 ? 192 THR B C   1 
ATOM   4603  O O   . THR B 1 192 ? 100.689 103.742 134.144 1.00 44.68 ? 192 THR B O   1 
ATOM   4604  C CB  . THR B 1 192 ? 102.197 106.121 135.250 1.00 44.68 ? 192 THR B CB  1 
ATOM   4605  O OG1 . THR B 1 192 ? 103.089 105.498 134.323 1.00 44.68 ? 192 THR B OG1 1 
ATOM   4606  C CG2 . THR B 1 192 ? 102.998 106.982 136.208 1.00 44.68 ? 192 THR B CG2 1 
ATOM   4607  N N   . ALA B 1 193 ? 99.118  104.715 135.429 1.00 45.58 ? 193 ALA B N   1 
ATOM   4608  C CA  . ALA B 1 193 ? 97.992  104.302 134.615 1.00 45.58 ? 193 ALA B CA  1 
ATOM   4609  C C   . ALA B 1 193 ? 97.346  105.527 133.992 1.00 45.58 ? 193 ALA B C   1 
ATOM   4610  O O   . ALA B 1 193 ? 97.037  106.495 134.687 1.00 45.58 ? 193 ALA B O   1 
ATOM   4611  C CB  . ALA B 1 193 ? 96.968  103.530 135.440 1.00 45.58 ? 193 ALA B CB  1 
ATOM   4612  N N   . LEU B 1 194 ? 97.152  105.480 132.686 1.00 43.85 ? 194 LEU B N   1 
ATOM   4613  C CA  . LEU B 1 194 ? 96.461  106.517 131.947 1.00 43.85 ? 194 LEU B CA  1 
ATOM   4614  C C   . LEU B 1 194 ? 95.022  106.083 131.759 1.00 43.85 ? 194 LEU B C   1 
ATOM   4615  O O   . LEU B 1 194 ? 94.766  104.971 131.291 1.00 43.85 ? 194 LEU B O   1 
ATOM   4616  C CB  . LEU B 1 194 ? 97.110  106.739 130.584 1.00 43.85 ? 194 LEU B CB  1 
ATOM   4617  C CG  . LEU B 1 194 ? 98.401  107.536 130.436 1.00 43.85 ? 194 LEU B CG  1 
ATOM   4618  C CD1 . LEU B 1 194 ? 98.160  108.967 130.819 1.00 43.85 ? 194 LEU B CD1 1 
ATOM   4619  C CD2 . LEU B 1 194 ? 99.537  106.937 131.246 1.00 43.85 ? 194 LEU B CD2 1 
ATOM   4620  N N   . ASP B 1 195 ? 94.088  106.936 132.143 1.00 49.74 ? 195 ASP B N   1 
ATOM   4621  C CA  . ASP B 1 195 ? 92.695  106.764 131.754 1.00 49.74 ? 195 ASP B CA  1 
ATOM   4622  C C   . ASP B 1 195 ? 92.519  107.600 130.502 1.00 49.74 ? 195 ASP B C   1 
ATOM   4623  O O   . ASP B 1 195 ? 92.567  108.828 130.567 1.00 49.74 ? 195 ASP B O   1 
ATOM   4624  C CB  . ASP B 1 195 ? 91.749  107.218 132.857 1.00 49.74 ? 195 ASP B CB  1 
ATOM   4625  C CG  . ASP B 1 195 ? 91.843  106.361 134.101 1.00 49.74 ? 195 ASP B CG  1 
ATOM   4626  O OD1 . ASP B 1 195 ? 92.186  105.166 133.994 1.00 49.74 ? 195 ASP B OD1 1 
ATOM   4627  O OD2 . ASP B 1 195 ? 91.562  106.888 135.195 1.00 49.74 ? 195 ASP B OD2 1 
ATOM   4628  N N   . MET B 1 196 ? 92.370  106.949 129.348 1.00 48.06 ? 196 MET B N   1 
ATOM   4629  C CA  . MET B 1 196 ? 92.265  107.695 128.098 1.00 48.06 ? 196 MET B CA  1 
ATOM   4630  C C   . MET B 1 196 ? 90.794  108.032 127.888 1.00 48.06 ? 196 MET B C   1 
ATOM   4631  O O   . MET B 1 196 ? 90.059  107.339 127.183 1.00 48.06 ? 196 MET B O   1 
ATOM   4632  C CB  . MET B 1 196 ? 92.826  106.892 126.934 1.00 48.06 ? 196 MET B CB  1 
ATOM   4633  C CG  . MET B 1 196 ? 94.304  106.647 126.982 1.00 48.06 ? 196 MET B CG  1 
ATOM   4634  S SD  . MET B 1 196 ? 95.211  108.181 126.951 1.00 48.06 ? 196 MET B SD  1 
ATOM   4635  C CE  . MET B 1 196 ? 96.881  107.568 126.890 1.00 48.06 ? 196 MET B CE  1 
ATOM   4636  N N   . GLN B 1 197 ? 90.357  109.111 128.528 1.00 47.49 ? 197 GLN B N   1 
ATOM   4637  C CA  . GLN B 1 197 ? 88.946  109.456 128.488 1.00 47.49 ? 197 GLN B CA  1 
ATOM   4638  C C   . GLN B 1 197 ? 88.472  109.609 127.056 1.00 47.49 ? 197 GLN B C   1 
ATOM   4639  O O   . GLN B 1 197 ? 89.225  110.028 126.176 1.00 47.49 ? 197 GLN B O   1 
ATOM   4640  C CB  . GLN B 1 197 ? 88.677  110.743 129.257 1.00 47.49 ? 197 GLN B CB  1 
ATOM   4641  C CG  . GLN B 1 197 ? 88.292  110.534 130.697 1.00 47.49 ? 197 GLN B CG  1 
ATOM   4642  C CD  . GLN B 1 197 ? 89.480  110.238 131.566 1.00 47.49 ? 197 GLN B CD  1 
ATOM   4643  O OE1 . GLN B 1 197 ? 90.616  110.435 131.159 1.00 47.49 ? 197 GLN B OE1 1 
ATOM   4644  N NE2 . GLN B 1 197 ? 89.229  109.759 132.774 1.00 47.49 ? 197 GLN B NE2 1 
ATOM   4645  N N   . ARG B 1 198 ? 87.213  109.235 126.826 1.00 51.82 ? 198 ARG B N   1 
ATOM   4646  C CA  . ARG B 1 198 ? 86.580  109.450 125.536 1.00 51.82 ? 198 ARG B CA  1 
ATOM   4647  C C   . ARG B 1 198 ? 86.509  110.927 125.188 1.00 51.82 ? 198 ARG B C   1 
ATOM   4648  O O   . ARG B 1 198 ? 86.358  111.274 124.014 1.00 51.82 ? 198 ARG B O   1 
ATOM   4649  C CB  . ARG B 1 198 ? 85.181  108.840 125.536 1.00 51.82 ? 198 ARG B CB  1 
ATOM   4650  C CG  . ARG B 1 198 ? 84.501  108.873 124.195 1.00 51.82 ? 198 ARG B CG  1 
ATOM   4651  C CD  . ARG B 1 198 ? 83.169  108.180 124.227 1.00 51.82 ? 198 ARG B CD  1 
ATOM   4652  N NE  . ARG B 1 198 ? 83.305  106.788 124.622 1.00 51.82 ? 198 ARG B NE  1 
ATOM   4653  C CZ  . ARG B 1 198 ? 82.315  105.907 124.588 1.00 51.82 ? 198 ARG B CZ  1 
ATOM   4654  N NH1 . ARG B 1 198 ? 81.121  106.269 124.145 1.00 51.82 ? 198 ARG B NH1 1 
ATOM   4655  N NH2 . ARG B 1 198 ? 82.525  104.658 124.970 1.00 51.82 ? 198 ARG B NH2 1 
ATOM   4656  N N   . SER B 1 199 ? 86.636  111.806 126.181 1.00 51.88 ? 199 SER B N   1 
ATOM   4657  C CA  . SER B 1 199 ? 86.660  113.244 125.959 1.00 51.88 ? 199 SER B CA  1 
ATOM   4658  C C   . SER B 1 199 ? 88.070  113.781 125.746 1.00 51.88 ? 199 SER B C   1 
ATOM   4659  O O   . SER B 1 199 ? 88.342  114.941 126.075 1.00 51.88 ? 199 SER B O   1 
ATOM   4660  C CB  . SER B 1 199 ? 85.983  113.957 127.125 1.00 51.88 ? 199 SER B CB  1 
ATOM   4661  O OG  . SER B 1 199 ? 84.628  113.556 127.222 1.00 51.88 ? 199 SER B OG  1 
ATOM   4662  N N   . ALA B 1 200 ? 88.980  112.950 125.242 1.00 46.37 ? 200 ALA B N   1 
ATOM   4663  C CA  . ALA B 1 200 ? 90.322  113.357 124.849 1.00 46.37 ? 200 ALA B CA  1 
ATOM   4664  C C   . ALA B 1 200 ? 91.145  113.872 126.019 1.00 46.37 ? 200 ALA B C   1 
ATOM   4665  O O   . ALA B 1 200 ? 92.296  114.279 125.840 1.00 46.37 ? 200 ALA B O   1 
ATOM   4666  C CB  . ALA B 1 200 ? 90.256  114.420 123.756 1.00 46.37 ? 200 ALA B CB  1 
ATOM   4667  N N   . ALA B 1 201 ? 90.581  113.837 127.218 1.00 47.89 ? 201 ALA B N   1 
ATOM   4668  C CA  . ALA B 1 201 ? 91.199  114.415 128.405 1.00 47.89 ? 201 ALA B CA  1 
ATOM   4669  C C   . ALA B 1 201 ? 91.799  113.293 129.244 1.00 47.89 ? 201 ALA B C   1 
ATOM   4670  O O   . ALA B 1 201 ? 91.203  112.853 130.224 1.00 47.89 ? 201 ALA B O   1 
ATOM   4671  C CB  . ALA B 1 201 ? 90.174  115.214 129.200 1.00 47.89 ? 201 ALA B CB  1 
ATOM   4672  N N   . CYS B 1 202 ? 92.996  112.851 128.875 1.00 48.95 ? 202 CYS B N   1 
ATOM   4673  C CA  . CYS B 1 202 ? 93.627  111.728 129.559 1.00 48.95 ? 202 CYS B CA  1 
ATOM   4674  C C   . CYS B 1 202 ? 93.980  112.099 130.991 1.00 48.95 ? 202 CYS B C   1 
ATOM   4675  O O   . CYS B 1 202 ? 94.387  113.228 131.270 1.00 48.95 ? 202 CYS B O   1 
ATOM   4676  C CB  . CYS B 1 202 ? 94.876  111.276 128.805 1.00 48.95 ? 202 CYS B CB  1 
ATOM   4677  S SG  . CYS B 1 202 ? 96.163  112.515 128.693 1.00 48.95 ? 202 CYS B SG  1 
ATOM   4678  N N   . THR B 1 203 ? 93.815  111.144 131.902 1.00 44.48 ? 203 THR B N   1 
ATOM   4679  C CA  . THR B 1 203 ? 94.005  111.387 133.328 1.00 44.48 ? 203 THR B CA  1 
ATOM   4680  C C   . THR B 1 203 ? 95.000  110.399 133.920 1.00 44.48 ? 203 THR B C   1 
ATOM   4681  O O   . THR B 1 203 ? 94.831  109.186 133.787 1.00 44.48 ? 203 THR B O   1 
ATOM   4682  C CB  . THR B 1 203 ? 92.678  111.303 134.070 1.00 44.48 ? 203 THR B CB  1 
ATOM   4683  O OG1 . THR B 1 203 ? 91.857  112.410 133.688 1.00 44.48 ? 203 THR B OG1 1 
ATOM   4684  C CG2 . THR B 1 203 ? 92.906  111.352 135.559 1.00 44.48 ? 203 THR B CG2 1 
ATOM   4685  N N   . LEU B 1 204 ? 96.011  110.924 134.602 1.00 42.26 ? 204 LEU B N   1 
ATOM   4686  C CA  . LEU B 1 204 ? 97.087  110.127 135.169 1.00 42.26 ? 204 LEU B CA  1 
ATOM   4687  C C   . LEU B 1 204 ? 96.723  109.595 136.556 1.00 42.26 ? 204 LEU B C   1 
ATOM   4688  O O   . LEU B 1 204 ? 96.000  110.236 137.320 1.00 42.26 ? 204 LEU B O   1 
ATOM   4689  C CB  . LEU B 1 204 ? 98.359  110.964 135.247 1.00 42.26 ? 204 LEU B CB  1 
ATOM   4690  C CG  . LEU B 1 204 ? 99.634  110.271 135.690 1.00 42.26 ? 204 LEU B CG  1 
ATOM   4691  C CD1 . LEU B 1 204 ? 99.783  108.997 134.928 1.00 42.26 ? 204 LEU B CD1 1 
ATOM   4692  C CD2 . LEU B 1 204 ? 100.810 111.162 135.427 1.00 42.26 ? 204 LEU B CD2 1 
ATOM   4693  N N   . LYS B 1 205 ? 97.221  108.396 136.863 1.00 45.87 ? 205 LYS B N   1 
ATOM   4694  C CA  . LYS B 1 205 ? 97.082  107.770 138.168 1.00 45.87 ? 205 LYS B CA  1 
ATOM   4695  C C   . LYS B 1 205 ? 98.418  107.164 138.542 1.00 45.87 ? 205 LYS B C   1 
ATOM   4696  O O   . LYS B 1 205 ? 99.078  106.560 137.697 1.00 45.87 ? 205 LYS B O   1 
ATOM   4697  C CB  . LYS B 1 205 ? 96.022  106.675 138.163 1.00 45.87 ? 205 LYS B CB  1 
ATOM   4698  C CG  . LYS B 1 205 ? 94.984  106.838 137.090 1.00 45.87 ? 205 LYS B CG  1 
ATOM   4699  C CD  . LYS B 1 205 ? 93.751  106.039 137.400 1.00 45.87 ? 205 LYS B CD  1 
ATOM   4700  C CE  . LYS B 1 205 ? 94.007  104.565 137.240 1.00 45.87 ? 205 LYS B CE  1 
ATOM   4701  N NZ  . LYS B 1 205 ? 92.743  103.792 137.313 1.00 45.87 ? 205 LYS B NZ  1 
ATOM   4702  N N   . THR B 1 206 ? 98.814  107.306 139.801 1.00 49.88 ? 206 THR B N   1 
ATOM   4703  C CA  . THR B 1 206 ? 100.128 106.863 140.235 1.00 49.88 ? 206 THR B CA  1 
ATOM   4704  C C   . THR B 1 206 ? 99.993  105.903 141.402 1.00 49.88 ? 206 THR B C   1 
ATOM   4705  O O   . THR B 1 206 ? 99.208  106.133 142.325 1.00 49.88 ? 206 THR B O   1 
ATOM   4706  C CB  . THR B 1 206 ? 101.011 108.046 140.642 1.00 49.88 ? 206 THR B CB  1 
ATOM   4707  O OG1 . THR B 1 206 ? 100.918 109.072 139.651 1.00 49.88 ? 206 THR B OG1 1 
ATOM   4708  C CG2 . THR B 1 206 ? 102.453 107.620 140.760 1.00 49.88 ? 206 THR B CG2 1 
ATOM   4709  N N   . ALA B 1 207 ? 100.773 104.835 141.359 1.00 51.93 ? 207 ALA B N   1 
ATOM   4710  C CA  . ALA B 1 207 ? 100.833 103.864 142.434 1.00 51.93 ? 207 ALA B CA  1 
ATOM   4711  C C   . ALA B 1 207 ? 102.259 103.757 142.938 1.00 51.93 ? 207 ALA B C   1 
ATOM   4712  O O   . ALA B 1 207 ? 103.208 103.737 142.143 1.00 51.93 ? 207 ALA B O   1 
ATOM   4713  C CB  . ALA B 1 207 ? 100.348 102.502 141.975 1.00 51.93 ? 207 ALA B CB  1 
ATOM   4714  N N   . PHE B 1 208 ? 102.393 103.678 144.259 1.00 52.47 ? 208 PHE B N   1 
ATOM   4715  C CA  . PHE B 1 208 ? 103.678 103.582 144.941 1.00 52.47 ? 208 PHE B CA  1 
ATOM   4716  C C   . PHE B 1 208 ? 103.759 102.252 145.678 1.00 52.47 ? 208 PHE B C   1 
ATOM   4717  O O   . PHE B 1 208 ? 102.982 102.016 146.621 1.00 52.47 ? 208 PHE B O   1 
ATOM   4718  C CB  . PHE B 1 208 ? 103.848 104.739 145.921 1.00 52.47 ? 208 PHE B CB  1 
ATOM   4719  C CG  . PHE B 1 208 ? 104.267 106.035 145.283 1.00 52.47 ? 208 PHE B CG  1 
ATOM   4720  C CD1 . PHE B 1 208 ? 105.417 106.115 144.524 1.00 52.47 ? 208 PHE B CD1 1 
ATOM   4721  C CD2 . PHE B 1 208 ? 103.520 107.180 145.468 1.00 52.47 ? 208 PHE B CD2 1 
ATOM   4722  C CE1 . PHE B 1 208 ? 105.797 107.312 143.950 1.00 52.47 ? 208 PHE B CE1 1 
ATOM   4723  C CE2 . PHE B 1 208 ? 103.898 108.370 144.895 1.00 52.47 ? 208 PHE B CE2 1 
ATOM   4724  C CZ  . PHE B 1 208 ? 105.034 108.436 144.139 1.00 52.47 ? 208 PHE B CZ  1 
ATOM   4725  N N   . PRO B 1 209 ? 104.619 101.333 145.248 1.00 55.11 ? 209 PRO B N   1 
ATOM   4726  C CA  . PRO B 1 209 ? 104.964 100.190 146.073 1.00 55.11 ? 209 PRO B CA  1 
ATOM   4727  C C   . PRO B 1 209 ? 106.119 100.525 146.993 1.00 55.11 ? 209 PRO B C   1 
ATOM   4728  O O   . PRO B 1 209 ? 107.224 100.842 146.530 1.00 55.11 ? 209 PRO B O   1 
ATOM   4729  C CB  . PRO B 1 209 ? 105.369 99.121  145.047 1.00 55.11 ? 209 PRO B CB  1 
ATOM   4730  C CG  . PRO B 1 209 ? 105.028 99.677  143.724 1.00 55.11 ? 209 PRO B CG  1 
ATOM   4731  C CD  . PRO B 1 209 ? 105.098 101.144 143.876 1.00 55.11 ? 209 PRO B CD  1 
ATOM   4732  N N   . PRO B 1 210 ? 105.909 100.457 148.303 1.00 59.81 ? 210 PRO B N   1 
ATOM   4733  C CA  . PRO B 1 210 ? 106.935 100.875 149.264 1.00 59.81 ? 210 PRO B CA  1 
ATOM   4734  C C   . PRO B 1 210 ? 108.000 99.835  149.567 1.00 59.81 ? 210 PRO B C   1 
ATOM   4735  O O   . PRO B 1 210 ? 108.648 99.948  150.609 1.00 59.81 ? 210 PRO B O   1 
ATOM   4736  C CB  . PRO B 1 210 ? 106.109 101.161 150.524 1.00 59.81 ? 210 PRO B CB  1 
ATOM   4737  C CG  . PRO B 1 210 ? 104.697 101.137 150.103 1.00 59.81 ? 210 PRO B CG  1 
ATOM   4738  C CD  . PRO B 1 210 ? 104.620 100.229 148.953 1.00 59.81 ? 210 PRO B CD  1 
ATOM   4739  N N   . LEU B 1 211 ? 108.181 98.827  148.717 1.00 60.62 ? 211 LEU B N   1 
ATOM   4740  C CA  . LEU B 1 211 ? 109.065 97.723  149.071 1.00 60.62 ? 211 LEU B CA  1 
ATOM   4741  C C   . LEU B 1 211 ? 110.493 98.193  149.313 1.00 60.62 ? 211 LEU B C   1 
ATOM   4742  O O   . LEU B 1 211 ? 111.123 97.789  150.296 1.00 60.62 ? 211 LEU B O   1 
ATOM   4743  C CB  . LEU B 1 211 ? 109.036 96.653  147.987 1.00 60.62 ? 211 LEU B CB  1 
ATOM   4744  C CG  . LEU B 1 211 ? 109.837 95.421  148.386 1.00 60.62 ? 211 LEU B CG  1 
ATOM   4745  C CD1 . LEU B 1 211 ? 109.260 94.840  149.651 1.00 60.62 ? 211 LEU B CD1 1 
ATOM   4746  C CD2 . LEU B 1 211 ? 109.840 94.400  147.280 1.00 60.62 ? 211 LEU B CD2 1 
ATOM   4747  N N   . LEU B 1 212 ? 111.026 99.047  148.438 1.00 60.91 ? 212 LEU B N   1 
ATOM   4748  C CA  . LEU B 1 212 ? 112.372 99.562  148.662 1.00 60.91 ? 212 LEU B CA  1 
ATOM   4749  C C   . LEU B 1 212 ? 112.421 100.450 149.897 1.00 60.91 ? 212 LEU B C   1 
ATOM   4750  O O   . LEU B 1 212 ? 113.406 100.437 150.643 1.00 60.91 ? 212 LEU B O   1 
ATOM   4751  C CB  . LEU B 1 212 ? 112.857 100.333 147.440 1.00 60.91 ? 212 LEU B CB  1 
ATOM   4752  C CG  . LEU B 1 212 ? 112.720 99.668  146.078 1.00 60.91 ? 212 LEU B CG  1 
ATOM   4753  C CD1 . LEU B 1 212 ? 112.811 100.712 145.003 1.00 60.91 ? 212 LEU B CD1 1 
ATOM   4754  C CD2 . LEU B 1 212 ? 113.800 98.645  145.893 1.00 60.91 ? 212 LEU B CD2 1 
ATOM   4755  N N   . ARG B 1 213 ? 111.367 101.232 150.127 1.00 62.66 ? 213 ARG B N   1 
ATOM   4756  C CA  . ARG B 1 213 ? 111.297 102.048 151.334 1.00 62.66 ? 213 ARG B CA  1 
ATOM   4757  C C   . ARG B 1 213 ? 111.307 101.179 152.581 1.00 62.66 ? 213 ARG B C   1 
ATOM   4758  O O   . ARG B 1 213 ? 112.166 101.334 153.457 1.00 62.66 ? 213 ARG B O   1 
ATOM   4759  C CB  . ARG B 1 213 ? 110.041 102.909 151.308 1.00 62.66 ? 213 ARG B CB  1 
ATOM   4760  C CG  . ARG B 1 213 ? 109.777 103.625 152.602 1.00 62.66 ? 213 ARG B CG  1 
ATOM   4761  C CD  . ARG B 1 213 ? 110.885 104.602 152.893 1.00 62.66 ? 213 ARG B CD  1 
ATOM   4762  N NE  . ARG B 1 213 ? 110.807 105.776 152.036 1.00 62.66 ? 213 ARG B NE  1 
ATOM   4763  C CZ  . ARG B 1 213 ? 111.791 106.651 151.874 1.00 62.66 ? 213 ARG B CZ  1 
ATOM   4764  N NH1 . ARG B 1 213 ? 112.941 106.485 152.508 1.00 62.66 ? 213 ARG B NH1 1 
ATOM   4765  N NH2 . ARG B 1 213 ? 111.624 107.692 151.073 1.00 62.66 ? 213 ARG B NH2 1 
ATOM   4766  N N   . SER B 1 214 ? 110.342 100.266 152.683 1.00 64.14 ? 214 SER B N   1 
ATOM   4767  C CA  . SER B 1 214 ? 110.283 99.368  153.825 1.00 64.14 ? 214 SER B CA  1 
ATOM   4768  C C   . SER B 1 214 ? 111.548 98.545  153.957 1.00 64.14 ? 214 SER B C   1 
ATOM   4769  O O   . SER B 1 214 ? 111.854 98.050  155.045 1.00 64.14 ? 214 SER B O   1 
ATOM   4770  C CB  . SER B 1 214 ? 109.079 98.450  153.698 1.00 64.14 ? 214 SER B CB  1 
ATOM   4771  O OG  . SER B 1 214 ? 109.039 97.862  152.415 1.00 64.14 ? 214 SER B OG  1 
ATOM   4772  N N   . THR B 1 215 ? 112.293 98.378  152.871 1.00 61.87 ? 215 THR B N   1 
ATOM   4773  C CA  . THR B 1 215 ? 113.530 97.620  152.958 1.00 61.87 ? 215 THR B CA  1 
ATOM   4774  C C   . THR B 1 215 ? 114.638 98.450  153.585 1.00 61.87 ? 215 THR B C   1 
ATOM   4775  O O   . THR B 1 215 ? 115.236 98.044  154.587 1.00 61.87 ? 215 THR B O   1 
ATOM   4776  C CB  . THR B 1 215 ? 113.937 97.128  151.578 1.00 61.87 ? 215 THR B CB  1 
ATOM   4777  O OG1 . THR B 1 215 ? 112.974 96.177  151.118 1.00 61.87 ? 215 THR B OG1 1 
ATOM   4778  C CG2 . THR B 1 215 ? 115.287 96.467  151.639 1.00 61.87 ? 215 THR B CG2 1 
ATOM   4779  N N   . ILE B 1 216 ? 114.928 99.619  153.012 1.00 64.86 ? 216 ILE B N   1 
ATOM   4780  C CA  . ILE B 1 216 ? 116.026 100.429 153.532 1.00 64.86 ? 216 ILE B CA  1 
ATOM   4781  C C   . ILE B 1 216 ? 115.730 100.875 154.954 1.00 64.86 ? 216 ILE B C   1 
ATOM   4782  O O   . ILE B 1 216 ? 116.601 100.822 155.828 1.00 64.86 ? 216 ILE B O   1 
ATOM   4783  C CB  . ILE B 1 216 ? 116.309 101.630 152.613 1.00 64.86 ? 216 ILE B CB  1 
ATOM   4784  C CG1 . ILE B 1 216 ? 115.020 102.389 152.297 1.00 64.86 ? 216 ILE B CG1 1 
ATOM   4785  C CG2 . ILE B 1 216 ? 117.010 101.175 151.349 1.00 64.86 ? 216 ILE B CG2 1 
ATOM   4786  C CD1 . ILE B 1 216 ? 115.209 103.551 151.362 1.00 64.86 ? 216 ILE B CD1 1 
ATOM   4787  N N   . MET B 1 217 ? 114.502 101.311 155.216 1.00 67.72 ? 217 MET B N   1 
ATOM   4788  C CA  . MET B 1 217 ? 114.126 101.664 156.573 1.00 67.72 ? 217 MET B CA  1 
ATOM   4789  C C   . MET B 1 217 ? 113.958 100.445 157.463 1.00 67.72 ? 217 MET B C   1 
ATOM   4790  O O   . MET B 1 217 ? 113.875 100.599 158.683 1.00 67.72 ? 217 MET B O   1 
ATOM   4791  C CB  . MET B 1 217 ? 112.838 102.485 156.561 1.00 67.72 ? 217 MET B CB  1 
ATOM   4792  C CG  . MET B 1 217 ? 112.982 103.819 155.856 1.00 67.72 ? 217 MET B CG  1 
ATOM   4793  S SD  . MET B 1 217 ? 111.728 105.010 156.344 1.00 67.72 ? 217 MET B SD  1 
ATOM   4794  C CE  . MET B 1 217 ? 111.861 104.918 158.123 1.00 67.72 ? 217 MET B CE  1 
ATOM   4795  N N   . ASN B 1 218 ? 113.919 99.248  156.881 1.00 70.12 ? 218 ASN B N   1 
ATOM   4796  C CA  . ASN B 1 218 ? 113.818 98.000  157.634 1.00 70.12 ? 218 ASN B CA  1 
ATOM   4797  C C   . ASN B 1 218 ? 112.577 97.980  158.517 1.00 70.12 ? 218 ASN B C   1 
ATOM   4798  O O   . ASN B 1 218 ? 112.571 97.389  159.596 1.00 70.12 ? 218 ASN B O   1 
ATOM   4799  C CB  . ASN B 1 218 ? 115.078 97.751  158.462 1.00 70.12 ? 218 ASN B CB  1 
ATOM   4800  C CG  . ASN B 1 218 ? 116.291 97.476  157.603 1.00 70.12 ? 218 ASN B CG  1 
ATOM   4801  O OD1 . ASN B 1 218 ? 116.622 96.324  157.328 1.00 70.12 ? 218 ASN B OD1 1 
ATOM   4802  N ND2 . ASN B 1 218 ? 116.962 98.536  157.171 1.00 70.12 ? 218 ASN B ND2 1 
ATOM   4803  N N   . THR B 1 219 ? 111.516 98.629  158.057 1.00 69.38 ? 219 THR B N   1 
ATOM   4804  C CA  . THR B 1 219 ? 110.244 98.613  158.752 1.00 69.38 ? 219 THR B CA  1 
ATOM   4805  C C   . THR B 1 219 ? 109.213 97.878  157.910 1.00 69.38 ? 219 THR B C   1 
ATOM   4806  O O   . THR B 1 219 ? 109.444 97.562  156.742 1.00 69.38 ? 219 THR B O   1 
ATOM   4807  C CB  . THR B 1 219 ? 109.744 100.021 159.048 1.00 69.38 ? 219 THR B CB  1 
ATOM   4808  O OG1 . THR B 1 219 ? 109.200 100.575 157.851 1.00 69.38 ? 219 THR B OG1 1 
ATOM   4809  C CG2 . THR B 1 219 ? 110.881 100.897 159.525 1.00 69.38 ? 219 THR B CG2 1 
ATOM   4810  N N   . SER B 1 220 ? 108.065 97.614  158.520 1.00 70.66 ? 220 SER B N   1 
ATOM   4811  C CA  . SER B 1 220 ? 107.034 96.838  157.851 1.00 70.66 ? 220 SER B CA  1 
ATOM   4812  C C   . SER B 1 220 ? 106.309 97.687  156.819 1.00 70.66 ? 220 SER B C   1 
ATOM   4813  O O   . SER B 1 220 ? 106.216 98.909  156.947 1.00 70.66 ? 220 SER B O   1 
ATOM   4814  C CB  . SER B 1 220 ? 106.044 96.284  158.870 1.00 70.66 ? 220 SER B CB  1 
ATOM   4815  O OG  . SER B 1 220 ? 106.681 95.358  159.728 1.00 70.66 ? 220 SER B OG  1 
ATOM   4816  N N   . MET B 1 221 ? 105.834 97.031  155.764 1.00 71.66 ? 221 MET B N   1 
ATOM   4817  C CA  . MET B 1 221 ? 105.067 97.730  154.743 1.00 71.66 ? 221 MET B CA  1 
ATOM   4818  C C   . MET B 1 221 ? 103.849 98.401  155.354 1.00 71.66 ? 221 MET B C   1 
ATOM   4819  O O   . MET B 1 221 ? 103.518 99.553  155.032 1.00 71.66 ? 221 MET B O   1 
ATOM   4820  C CB  . MET B 1 221 ? 104.645 96.743  153.658 1.00 71.66 ? 221 MET B CB  1 
ATOM   4821  C CG  . MET B 1 221 ? 105.736 95.774  153.226 1.00 71.66 ? 221 MET B CG  1 
ATOM   4822  S SD  . MET B 1 221 ? 106.904 96.449  152.035 1.00 71.66 ? 221 MET B SD  1 
ATOM   4823  C CE  . MET B 1 221 ? 105.841 96.719  150.628 1.00 71.66 ? 221 MET B CE  1 
ATOM   4824  N N   . VAL B 1 222 ? 103.174 97.683  156.250 1.00 72.88 ? 222 VAL B N   1 
ATOM   4825  C CA  . VAL B 1 222 ? 101.896 98.140  156.785 1.00 72.88 ? 222 VAL B CA  1 
ATOM   4826  C C   . VAL B 1 222 ? 102.021 99.546  157.344 1.00 72.88 ? 222 VAL B C   1 
ATOM   4827  O O   . VAL B 1 222 ? 101.323 100.473 156.915 1.00 72.88 ? 222 VAL B O   1 
ATOM   4828  C CB  . VAL B 1 222 ? 101.394 97.159  157.857 1.00 72.88 ? 222 VAL B CB  1 
ATOM   4829  C CG1 . VAL B 1 222 ? 99.938  97.435  158.184 1.00 72.88 ? 222 VAL B CG1 1 
ATOM   4830  C CG2 . VAL B 1 222 ? 101.591 95.740  157.382 1.00 72.88 ? 222 VAL B CG2 1 
ATOM   4831  N N   . ASP B 1 223 ? 102.942 99.730  158.286 1.00 74.35 ? 223 ASP B N   1 
ATOM   4832  C CA  . ASP B 1 223 ? 102.930 100.955 159.066 1.00 74.35 ? 223 ASP B CA  1 
ATOM   4833  C C   . ASP B 1 223 ? 103.552 102.117 158.303 1.00 74.35 ? 223 ASP B C   1 
ATOM   4834  O O   . ASP B 1 223 ? 103.154 103.261 158.512 1.00 74.35 ? 223 ASP B O   1 
ATOM   4835  C CB  . ASP B 1 223 ? 103.595 100.742 160.427 1.00 74.35 ? 223 ASP B CB  1 
ATOM   4836  C CG  . ASP B 1 223 ? 104.774 99.827  160.357 1.00 74.35 ? 223 ASP B CG  1 
ATOM   4837  O OD1 . ASP B 1 223 ? 105.177 99.490  159.231 1.00 74.35 ? 223 ASP B OD1 1 
ATOM   4838  O OD2 . ASP B 1 223 ? 105.301 99.449  161.421 1.00 74.35 ? 223 ASP B OD2 1 
ATOM   4839  N N   . ILE B 1 224 ? 104.516 101.875 157.411 1.00 69.18 ? 224 ILE B N   1 
ATOM   4840  C CA  . ILE B 1 224 ? 104.943 103.012 156.595 1.00 69.18 ? 224 ILE B CA  1 
ATOM   4841  C C   . ILE B 1 224 ? 103.798 103.492 155.719 1.00 69.18 ? 224 ILE B C   1 
ATOM   4842  O O   . ILE B 1 224 ? 103.526 104.697 155.635 1.00 69.18 ? 224 ILE B O   1 
ATOM   4843  C CB  . ILE B 1 224 ? 106.188 102.699 155.749 1.00 69.18 ? 224 ILE B CB  1 
ATOM   4844  C CG1 . ILE B 1 224 ? 106.028 101.422 154.954 1.00 69.18 ? 224 ILE B CG1 1 
ATOM   4845  C CG2 . ILE B 1 224 ? 107.412 102.645 156.609 1.00 69.18 ? 224 ILE B CG2 1 
ATOM   4846  C CD1 . ILE B 1 224 ? 107.122 101.253 153.972 1.00 69.18 ? 224 ILE B CD1 1 
ATOM   4847  N N   . MET B 1 225 ? 103.085 102.562 155.081 1.00 70.25 ? 225 MET B N   1 
ATOM   4848  C CA  . MET B 1 225 ? 101.944 102.960 154.266 1.00 70.25 ? 225 MET B CA  1 
ATOM   4849  C C   . MET B 1 225 ? 100.938 103.750 155.090 1.00 70.25 ? 225 MET B C   1 
ATOM   4850  O O   . MET B 1 225 ? 100.492 104.835 154.689 1.00 70.25 ? 225 MET B O   1 
ATOM   4851  C CB  . MET B 1 225 ? 101.287 101.725 153.656 1.00 70.25 ? 225 MET B CB  1 
ATOM   4852  C CG  . MET B 1 225 ? 102.080 101.100 152.526 1.00 70.25 ? 225 MET B CG  1 
ATOM   4853  S SD  . MET B 1 225 ? 101.195 99.762  151.715 1.00 70.25 ? 225 MET B SD  1 
ATOM   4854  C CE  . MET B 1 225 ? 102.535 98.636  151.347 1.00 70.25 ? 225 MET B CE  1 
ATOM   4855  N N   . PHE B 1 226 ? 100.594 103.238 156.266 1.00 71.28 ? 226 PHE B N   1 
ATOM   4856  C CA  . PHE B 1 226 ? 99.511  103.852 157.019 1.00 71.28 ? 226 PHE B CA  1 
ATOM   4857  C C   . PHE B 1 226 ? 99.951  105.100 157.765 1.00 71.28 ? 226 PHE B C   1 
ATOM   4858  O O   . PHE B 1 226 ? 99.143  106.004 157.970 1.00 71.28 ? 226 PHE B O   1 
ATOM   4859  C CB  . PHE B 1 226 ? 98.898  102.823 157.952 1.00 71.28 ? 226 PHE B CB  1 
ATOM   4860  C CG  . PHE B 1 226 ? 98.045  101.836 157.235 1.00 71.28 ? 226 PHE B CG  1 
ATOM   4861  C CD1 . PHE B 1 226 ? 96.911  102.255 156.567 1.00 71.28 ? 226 PHE B CD1 1 
ATOM   4862  C CD2 . PHE B 1 226 ? 98.392  100.502 157.185 1.00 71.28 ? 226 PHE B CD2 1 
ATOM   4863  C CE1 . PHE B 1 226 ? 96.126  101.357 155.890 1.00 71.28 ? 226 PHE B CE1 1 
ATOM   4864  C CE2 . PHE B 1 226 ? 97.611  99.598  156.510 1.00 71.28 ? 226 PHE B CE2 1 
ATOM   4865  C CZ  . PHE B 1 226 ? 96.477  100.026 155.860 1.00 71.28 ? 226 PHE B CZ  1 
ATOM   4866  N N   . ASP B 1 227 ? 101.224 105.207 158.127 1.00 69.24 ? 227 ASP B N   1 
ATOM   4867  C CA  . ASP B 1 227 ? 101.718 106.450 158.691 1.00 69.24 ? 227 ASP B CA  1 
ATOM   4868  C C   . ASP B 1 227 ? 101.771 107.539 157.635 1.00 69.24 ? 227 ASP B C   1 
ATOM   4869  O O   . ASP B 1 227 ? 101.505 108.709 157.931 1.00 69.24 ? 227 ASP B O   1 
ATOM   4870  C CB  . ASP B 1 227 ? 103.092 106.230 159.313 1.00 69.24 ? 227 ASP B CB  1 
ATOM   4871  C CG  . ASP B 1 227 ? 103.032 105.379 160.566 1.00 69.24 ? 227 ASP B CG  1 
ATOM   4872  O OD1 . ASP B 1 227 ? 101.937 104.872 160.889 1.00 69.24 ? 227 ASP B OD1 1 
ATOM   4873  O OD2 . ASP B 1 227 ? 104.079 105.213 161.224 1.00 69.24 ? 227 ASP B OD2 1 
ATOM   4874  N N   . ALA B 1 228 ? 102.098 107.177 156.394 1.00 65.38 ? 228 ALA B N   1 
ATOM   4875  C CA  . ALA B 1 228 ? 102.023 108.149 155.311 1.00 65.38 ? 228 ALA B CA  1 
ATOM   4876  C C   . ALA B 1 228 ? 100.594 108.635 155.118 1.00 65.38 ? 228 ALA B C   1 
ATOM   4877  O O   . ALA B 1 228 ? 100.338 109.844 155.054 1.00 65.38 ? 228 ALA B O   1 
ATOM   4878  C CB  . ALA B 1 228 ? 102.571 107.539 154.025 1.00 65.38 ? 228 ALA B CB  1 
ATOM   4879  N N   . VAL B 1 229 ? 99.640  107.707 155.035 1.00 69.32 ? 229 VAL B N   1 
ATOM   4880  C CA  . VAL B 1 229 ? 98.262  108.154 154.852 1.00 69.32 ? 229 VAL B CA  1 
ATOM   4881  C C   . VAL B 1 229 ? 97.787  108.951 156.062 1.00 69.32 ? 229 VAL B C   1 
ATOM   4882  O O   . VAL B 1 229 ? 96.983  109.878 155.926 1.00 69.32 ? 229 VAL B O   1 
ATOM   4883  C CB  . VAL B 1 229 ? 97.327  106.968 154.536 1.00 69.32 ? 229 VAL B CB  1 
ATOM   4884  C CG1 . VAL B 1 229 ? 97.035  106.153 155.767 1.00 69.32 ? 229 VAL B CG1 1 
ATOM   4885  C CG2 . VAL B 1 229 ? 96.034  107.478 153.938 1.00 69.32 ? 229 VAL B CG2 1 
ATOM   4886  N N   . GLU B 1 230 ? 98.315  108.655 157.251 1.00 72.08 ? 230 GLU B N   1 
ATOM   4887  C CA  . GLU B 1 230 ? 97.898  109.375 158.448 1.00 72.08 ? 230 GLU B CA  1 
ATOM   4888  C C   . GLU B 1 230 ? 98.428  110.801 158.452 1.00 72.08 ? 230 GLU B C   1 
ATOM   4889  O O   . GLU B 1 230 ? 97.697  111.752 158.769 1.00 72.08 ? 230 GLU B O   1 
ATOM   4890  C CB  . GLU B 1 230 ? 98.375  108.623 159.686 1.00 72.08 ? 230 GLU B CB  1 
ATOM   4891  C CG  . GLU B 1 230 ? 98.239  109.405 160.959 1.00 72.08 ? 230 GLU B CG  1 
ATOM   4892  C CD  . GLU B 1 230 ? 96.804  109.754 161.256 1.00 72.08 ? 230 GLU B CD  1 
ATOM   4893  O OE1 . GLU B 1 230 ? 95.918  108.939 160.939 1.00 72.08 ? 230 GLU B OE1 1 
ATOM   4894  O OE2 . GLU B 1 230 ? 96.558  110.846 161.801 1.00 72.08 ? 230 GLU B OE2 1 
ATOM   4895  N N   . SER B 1 231 ? 99.709  110.969 158.123 1.00 67.68 ? 231 SER B N   1 
ATOM   4896  C CA  . SER B 1 231 ? 100.258 112.314 158.034 1.00 67.68 ? 231 SER B CA  1 
ATOM   4897  C C   . SER B 1 231 ? 99.531  113.115 156.971 1.00 67.68 ? 231 SER B C   1 
ATOM   4898  O O   . SER B 1 231 ? 99.297  114.313 157.143 1.00 67.68 ? 231 SER B O   1 
ATOM   4899  C CB  . SER B 1 231 ? 101.754 112.274 157.736 1.00 67.68 ? 231 SER B CB  1 
ATOM   4900  O OG  . SER B 1 231 ? 101.996 111.911 156.396 1.00 67.68 ? 231 SER B OG  1 
ATOM   4901  N N   . PHE B 1 232 ? 99.152  112.472 155.866 1.00 66.91 ? 232 PHE B N   1 
ATOM   4902  C CA  . PHE B 1 232 ? 98.376  113.194 154.866 1.00 66.91 ? 232 PHE B CA  1 
ATOM   4903  C C   . PHE B 1 232 ? 97.011  113.575 155.408 1.00 66.91 ? 232 PHE B C   1 
ATOM   4904  O O   . PHE B 1 232 ? 96.502  114.660 155.118 1.00 66.91 ? 232 PHE B O   1 
ATOM   4905  C CB  . PHE B 1 232 ? 98.219  112.370 153.593 1.00 66.91 ? 232 PHE B CB  1 
ATOM   4906  C CG  . PHE B 1 232 ? 97.558  113.122 152.475 1.00 66.91 ? 232 PHE B CG  1 
ATOM   4907  C CD1 . PHE B 1 232 ? 98.237  114.118 151.802 1.00 66.91 ? 232 PHE B CD1 1 
ATOM   4908  C CD2 . PHE B 1 232 ? 96.257  112.848 152.112 1.00 66.91 ? 232 PHE B CD2 1 
ATOM   4909  C CE1 . PHE B 1 232 ? 97.635  114.817 150.787 1.00 66.91 ? 232 PHE B CE1 1 
ATOM   4910  C CE2 . PHE B 1 232 ? 95.653  113.546 151.097 1.00 66.91 ? 232 PHE B CE2 1 
ATOM   4911  C CZ  . PHE B 1 232 ? 96.344  114.532 150.435 1.00 66.91 ? 232 PHE B CZ  1 
ATOM   4912  N N   . ARG B 1 233 ? 96.399  112.690 156.191 1.00 75.15 ? 233 ARG B N   1 
ATOM   4913  C CA  . ARG B 1 233 ? 95.101  112.997 156.775 1.00 75.15 ? 233 ARG B CA  1 
ATOM   4914  C C   . ARG B 1 233 ? 95.168  114.237 157.649 1.00 75.15 ? 233 ARG B C   1 
ATOM   4915  O O   . ARG B 1 233 ? 94.281  115.095 157.599 1.00 75.15 ? 233 ARG B O   1 
ATOM   4916  C CB  . ARG B 1 233 ? 94.605  111.813 157.593 1.00 75.15 ? 233 ARG B CB  1 
ATOM   4917  C CG  . ARG B 1 233 ? 94.045  110.698 156.771 1.00 75.15 ? 233 ARG B CG  1 
ATOM   4918  C CD  . ARG B 1 233 ? 93.310  109.747 157.670 1.00 75.15 ? 233 ARG B CD  1 
ATOM   4919  N NE  . ARG B 1 233 ? 92.598  110.463 158.717 1.00 75.15 ? 233 ARG B NE  1 
ATOM   4920  C CZ  . ARG B 1 233 ? 91.861  109.873 159.647 1.00 75.15 ? 233 ARG B CZ  1 
ATOM   4921  N NH1 . ARG B 1 233 ? 91.743  108.555 159.661 1.00 75.15 ? 233 ARG B NH1 1 
ATOM   4922  N NH2 . ARG B 1 233 ? 91.244  110.603 160.564 1.00 75.15 ? 233 ARG B NH2 1 
ATOM   4923  N N   . LYS B 1 234 ? 96.215  114.348 158.460 1.00 73.53 ? 234 LYS B N   1 
ATOM   4924  C CA  . LYS B 1 234 ? 96.281  115.478 159.380 1.00 73.53 ? 234 LYS B CA  1 
ATOM   4925  C C   . LYS B 1 234 ? 96.726  116.750 158.671 1.00 73.53 ? 234 LYS B C   1 
ATOM   4926  O O   . LYS B 1 234 ? 96.150  117.821 158.885 1.00 73.53 ? 234 LYS B O   1 
ATOM   4927  C CB  . LYS B 1 234 ? 97.193  115.150 160.555 1.00 73.53 ? 234 LYS B CB  1 
ATOM   4928  C CG  . LYS B 1 234 ? 96.650  114.001 161.369 1.00 73.53 ? 234 LYS B CG  1 
ATOM   4929  C CD  . LYS B 1 234 ? 95.286  114.370 161.933 1.00 73.53 ? 234 LYS B CD  1 
ATOM   4930  C CE  . LYS B 1 234 ? 94.725  113.273 162.817 1.00 73.53 ? 234 LYS B CE  1 
ATOM   4931  N NZ  . LYS B 1 234 ? 94.347  112.068 162.027 1.00 73.53 ? 234 LYS B NZ  1 
ATOM   4932  N N   . GLN B 1 235 ? 97.739  116.654 157.810 1.00 72.09 ? 235 GLN B N   1 
ATOM   4933  C CA  . GLN B 1 235 ? 98.189  117.814 157.052 1.00 72.09 ? 235 GLN B CA  1 
ATOM   4934  C C   . GLN B 1 235 ? 97.115  118.342 156.112 1.00 72.09 ? 235 GLN B C   1 
ATOM   4935  O O   . GLN B 1 235 ? 97.096  119.539 155.820 1.00 72.09 ? 235 GLN B O   1 
ATOM   4936  C CB  . GLN B 1 235 ? 99.450  117.446 156.269 1.00 72.09 ? 235 GLN B CB  1 
ATOM   4937  C CG  . GLN B 1 235 ? 100.065 118.568 155.468 1.00 72.09 ? 235 GLN B CG  1 
ATOM   4938  C CD  . GLN B 1 235 ? 99.438  118.697 154.105 1.00 72.09 ? 235 GLN B CD  1 
ATOM   4939  O OE1 . GLN B 1 235 ? 98.850  117.749 153.593 1.00 72.09 ? 235 GLN B OE1 1 
ATOM   4940  N NE2 . GLN B 1 235 ? 99.552  119.873 153.509 1.00 72.09 ? 235 GLN B NE2 1 
ATOM   4941  N N   . SER B 1 236 ? 96.220  117.481 155.643 1.00 73.51 ? 236 SER B N   1 
ATOM   4942  C CA  . SER B 1 236 ? 95.182  117.872 154.704 1.00 73.51 ? 236 SER B CA  1 
ATOM   4943  C C   . SER B 1 236 ? 93.844  118.118 155.370 1.00 73.51 ? 236 SER B C   1 
ATOM   4944  O O   . SER B 1 236 ? 93.026  118.871 154.836 1.00 73.51 ? 236 SER B O   1 
ATOM   4945  C CB  . SER B 1 236 ? 95.008  116.789 153.636 1.00 73.51 ? 236 SER B CB  1 
ATOM   4946  O OG  . SER B 1 236 ? 94.661  115.549 154.226 1.00 73.51 ? 236 SER B OG  1 
ATOM   4947  N N   . GLY B 1 237 ? 93.606  117.504 156.524 1.00 77.50 ? 237 GLY B N   1 
ATOM   4948  C CA  . GLY B 1 237 ? 92.310  117.553 157.145 1.00 77.50 ? 237 GLY B CA  1 
ATOM   4949  C C   . GLY B 1 237 ? 91.277  116.656 156.511 1.00 77.50 ? 237 GLY B C   1 
ATOM   4950  O O   . GLY B 1 237 ? 90.203  116.468 157.094 1.00 77.50 ? 237 GLY B O   1 
ATOM   4951  N N   . LEU B 1 238 ? 91.556  116.095 155.341 1.00 77.40 ? 238 LEU B N   1 
ATOM   4952  C CA  . LEU B 1 238 ? 90.596  115.223 154.692 1.00 77.40 ? 238 LEU B CA  1 
ATOM   4953  C C   . LEU B 1 238 ? 90.578  113.859 155.375 1.00 77.40 ? 238 LEU B C   1 
ATOM   4954  O O   . LEU B 1 238 ? 91.533  113.453 156.039 1.00 77.40 ? 238 LEU B O   1 
ATOM   4955  C CB  . LEU B 1 238 ? 90.916  115.076 153.205 1.00 77.40 ? 238 LEU B CB  1 
ATOM   4956  C CG  . LEU B 1 238 ? 90.541  116.253 152.301 1.00 77.40 ? 238 LEU B CG  1 
ATOM   4957  C CD1 . LEU B 1 238 ? 91.523  117.399 152.430 1.00 77.40 ? 238 LEU B CD1 1 
ATOM   4958  C CD2 . LEU B 1 238 ? 90.444  115.812 150.867 1.00 77.40 ? 238 LEU B CD2 1 
ATOM   4959  N N   . TYR B 1 239 ? 89.470  113.148 155.194 1.00 81.52 ? 239 TYR B N   1 
ATOM   4960  C CA  . TYR B 1 239 ? 89.186  111.920 155.924 1.00 81.52 ? 239 TYR B CA  1 
ATOM   4961  C C   . TYR B 1 239 ? 89.515  110.718 155.049 1.00 81.52 ? 239 TYR B C   1 
ATOM   4962  O O   . TYR B 1 239 ? 88.965  110.581 153.955 1.00 81.52 ? 239 TYR B O   1 
ATOM   4963  C CB  . TYR B 1 239 ? 87.717  111.887 156.341 1.00 81.52 ? 239 TYR B CB  1 
ATOM   4964  C CG  . TYR B 1 239 ? 87.387  110.861 157.394 1.00 81.52 ? 239 TYR B CG  1 
ATOM   4965  C CD1 . TYR B 1 239 ? 87.491  109.505 157.127 1.00 81.52 ? 239 TYR B CD1 1 
ATOM   4966  C CD2 . TYR B 1 239 ? 86.948  111.248 158.648 1.00 81.52 ? 239 TYR B CD2 1 
ATOM   4967  C CE1 . TYR B 1 239 ? 87.192  108.567 158.082 1.00 81.52 ? 239 TYR B CE1 1 
ATOM   4968  C CE2 . TYR B 1 239 ? 86.639  110.315 159.610 1.00 81.52 ? 239 TYR B CE2 1 
ATOM   4969  C CZ  . TYR B 1 239 ? 86.764  108.975 159.322 1.00 81.52 ? 239 TYR B CZ  1 
ATOM   4970  O OH  . TYR B 1 239 ? 86.456  108.036 160.278 1.00 81.52 ? 239 TYR B OH  1 
ATOM   4971  N N   . PHE B 1 240 ? 90.388  109.838 155.534 1.00 78.12 ? 240 PHE B N   1 
ATOM   4972  C CA  . PHE B 1 240 ? 90.710  108.589 154.844 1.00 78.12 ? 240 PHE B CA  1 
ATOM   4973  C C   . PHE B 1 240 ? 90.664  107.459 155.866 1.00 78.12 ? 240 PHE B C   1 
ATOM   4974  O O   . PHE B 1 240 ? 91.685  107.145 156.483 1.00 78.12 ? 240 PHE B O   1 
ATOM   4975  C CB  . PHE B 1 240 ? 92.083  108.650 154.182 1.00 78.12 ? 240 PHE B CB  1 
ATOM   4976  C CG  . PHE B 1 240 ? 92.146  109.534 152.975 1.00 78.12 ? 240 PHE B CG  1 
ATOM   4977  C CD1 . PHE B 1 240 ? 91.206  109.429 151.970 1.00 78.12 ? 240 PHE B CD1 1 
ATOM   4978  C CD2 . PHE B 1 240 ? 93.164  110.452 152.832 1.00 78.12 ? 240 PHE B CD2 1 
ATOM   4979  C CE1 . PHE B 1 240 ? 91.275  110.234 150.857 1.00 78.12 ? 240 PHE B CE1 1 
ATOM   4980  C CE2 . PHE B 1 240 ? 93.231  111.258 151.720 1.00 78.12 ? 240 PHE B CE2 1 
ATOM   4981  C CZ  . PHE B 1 240 ? 92.285  111.149 150.736 1.00 78.12 ? 240 PHE B CZ  1 
ATOM   4982  N N   . ASP B 1 241 ? 89.503  106.834 156.043 1.00 81.46 ? 241 ASP B N   1 
ATOM   4983  C CA  . ASP B 1 241 ? 89.387  105.784 157.051 1.00 81.46 ? 241 ASP B CA  1 
ATOM   4984  C C   . ASP B 1 241 ? 90.303  104.628 156.674 1.00 81.46 ? 241 ASP B C   1 
ATOM   4985  O O   . ASP B 1 241 ? 90.057  103.929 155.689 1.00 81.46 ? 241 ASP B O   1 
ATOM   4986  C CB  . ASP B 1 241 ? 87.943  105.318 157.189 1.00 81.46 ? 241 ASP B CB  1 
ATOM   4987  C CG  . ASP B 1 241 ? 87.698  104.579 158.491 1.00 81.46 ? 241 ASP B CG  1 
ATOM   4988  O OD1 . ASP B 1 241 ? 87.827  105.206 159.563 1.00 81.46 ? 241 ASP B OD1 1 
ATOM   4989  O OD2 . ASP B 1 241 ? 87.384  103.371 158.443 1.00 81.46 ? 241 ASP B OD2 1 
ATOM   4990  N N   . TYR B 1 242 ? 91.358  104.426 157.462 1.00 77.23 ? 242 TYR B N   1 
ATOM   4991  C CA  . TYR B 1 242 ? 92.435  103.503 157.128 1.00 77.23 ? 242 TYR B CA  1 
ATOM   4992  C C   . TYR B 1 242 ? 92.677  102.456 158.204 1.00 77.23 ? 242 TYR B C   1 
ATOM   4993  O O   . TYR B 1 242 ? 93.668  101.725 158.124 1.00 77.23 ? 242 TYR B O   1 
ATOM   4994  C CB  . TYR B 1 242 ? 93.732  104.274 156.892 1.00 77.23 ? 242 TYR B CB  1 
ATOM   4995  C CG  . TYR B 1 242 ? 94.297  104.861 158.162 1.00 77.23 ? 242 TYR B CG  1 
ATOM   4996  C CD1 . TYR B 1 242 ? 93.825  106.061 158.658 1.00 77.23 ? 242 TYR B CD1 1 
ATOM   4997  C CD2 . TYR B 1 242 ? 95.294  104.208 158.870 1.00 77.23 ? 242 TYR B CD2 1 
ATOM   4998  C CE1 . TYR B 1 242 ? 94.333  106.600 159.819 1.00 77.23 ? 242 TYR B CE1 1 
ATOM   4999  C CE2 . TYR B 1 242 ? 95.807  104.739 160.034 1.00 77.23 ? 242 TYR B CE2 1 
ATOM   5000  C CZ  . TYR B 1 242 ? 95.323  105.936 160.502 1.00 77.23 ? 242 TYR B CZ  1 
ATOM   5001  O OH  . TYR B 1 242 ? 95.829  106.474 161.660 1.00 77.23 ? 242 TYR B OH  1 
ATOM   5002  N N   . THR B 1 243 ? 91.824  102.372 159.218 1.00 78.48 ? 243 THR B N   1 
ATOM   5003  C CA  . THR B 1 243 ? 92.129  101.495 160.340 1.00 78.48 ? 243 THR B CA  1 
ATOM   5004  C C   . THR B 1 243 ? 91.830  100.037 160.014 1.00 78.48 ? 243 THR B C   1 
ATOM   5005  O O   . THR B 1 243 ? 92.692  99.169  160.189 1.00 78.48 ? 243 THR B O   1 
ATOM   5006  C CB  . THR B 1 243 ? 91.372  101.959 161.584 1.00 78.48 ? 243 THR B CB  1 
ATOM   5007  O OG1 . THR B 1 243 ? 91.578  101.027 162.650 1.00 78.48 ? 243 THR B OG1 1 
ATOM   5008  C CG2 . THR B 1 243 ? 89.894  102.136 161.310 1.00 78.48 ? 243 THR B CG2 1 
ATOM   5009  N N   . LYS B 1 244 ? 90.642  99.753  159.481 1.00 76.04 ? 244 LYS B N   1 
ATOM   5010  C CA  . LYS B 1 244 ? 90.216  98.367  159.325 1.00 76.04 ? 244 LYS B CA  1 
ATOM   5011  C C   . LYS B 1 244 ? 91.176  97.592  158.440 1.00 76.04 ? 244 LYS B C   1 
ATOM   5012  O O   . LYS B 1 244 ? 91.524  96.441  158.742 1.00 76.04 ? 244 LYS B O   1 
ATOM   5013  C CB  . LYS B 1 244 ? 88.804  98.332  158.762 1.00 76.04 ? 244 LYS B CB  1 
ATOM   5014  C CG  . LYS B 1 244 ? 87.911  99.344  159.424 1.00 76.04 ? 244 LYS B CG  1 
ATOM   5015  C CD  . LYS B 1 244 ? 86.531  99.353  158.829 1.00 76.04 ? 244 LYS B CD  1 
ATOM   5016  C CE  . LYS B 1 244 ? 86.549  99.893  157.423 1.00 76.04 ? 244 LYS B CE  1 
ATOM   5017  N NZ  . LYS B 1 244 ? 85.171  100.110 156.911 1.00 76.04 ? 244 LYS B NZ  1 
ATOM   5018  N N   . ILE B 1 245 ? 91.636  98.219  157.357 1.00 75.91 ? 245 ILE B N   1 
ATOM   5019  C CA  . ILE B 1 245 ? 92.676  97.615  156.538 1.00 75.91 ? 245 ILE B CA  1 
ATOM   5020  C C   . ILE B 1 245 ? 93.874  97.274  157.398 1.00 75.91 ? 245 ILE B C   1 
ATOM   5021  O O   . ILE B 1 245 ? 94.477  96.206  157.257 1.00 75.91 ? 245 ILE B O   1 
ATOM   5022  C CB  . ILE B 1 245 ? 93.069  98.558  155.389 1.00 75.91 ? 245 ILE B CB  1 
ATOM   5023  C CG1 . ILE B 1 245 ? 91.845  98.999  154.600 1.00 75.91 ? 245 ILE B CG1 1 
ATOM   5024  C CG2 . ILE B 1 245 ? 94.052  97.890  154.461 1.00 75.91 ? 245 ILE B CG2 1 
ATOM   5025  C CD1 . ILE B 1 245 ? 92.186  99.924  153.459 1.00 75.91 ? 245 ILE B CD1 1 
ATOM   5026  N N   . LYS B 1 246 ? 94.225  98.167  158.319 1.00 76.73 ? 246 LYS B N   1 
ATOM   5027  C CA  . LYS B 1 246 ? 95.433  97.972  159.105 1.00 76.73 ? 246 LYS B CA  1 
ATOM   5028  C C   . LYS B 1 246 ? 95.286  96.795  160.059 1.00 76.73 ? 246 LYS B C   1 
ATOM   5029  O O   . LYS B 1 246 ? 96.148  95.908  160.095 1.00 76.73 ? 246 LYS B O   1 
ATOM   5030  C CB  . LYS B 1 246 ? 95.776  99.253  159.860 1.00 76.73 ? 246 LYS B CB  1 
ATOM   5031  C CG  . LYS B 1 246 ? 97.240  99.404  160.191 1.00 76.73 ? 246 LYS B CG  1 
ATOM   5032  C CD  . LYS B 1 246 ? 97.483  100.650 161.007 1.00 76.73 ? 246 LYS B CD  1 
ATOM   5033  C CE  . LYS B 1 246 ? 98.836  100.592 161.683 1.00 76.73 ? 246 LYS B CE  1 
ATOM   5034  N NZ  . LYS B 1 246 ? 98.999  101.673 162.688 1.00 76.73 ? 246 LYS B NZ  1 
ATOM   5035  N N   . GLU B 1 247 ? 94.199  96.750  160.832 1.00 79.39 ? 247 GLU B N   1 
ATOM   5036  C CA  . GLU B 1 247 ? 94.089  95.666  161.800 1.00 79.39 ? 247 GLU B CA  1 
ATOM   5037  C C   . GLU B 1 247 ? 93.737  94.352  161.121 1.00 79.39 ? 247 GLU B C   1 
ATOM   5038  O O   . GLU B 1 247 ? 93.804  93.293  161.751 1.00 79.39 ? 247 GLU B O   1 
ATOM   5039  C CB  . GLU B 1 247 ? 93.081  95.966  162.910 1.00 79.39 ? 247 GLU B CB  1 
ATOM   5040  C CG  . GLU B 1 247 ? 91.628  95.897  162.520 1.00 79.39 ? 247 GLU B CG  1 
ATOM   5041  C CD  . GLU B 1 247 ? 90.976  97.245  162.446 1.00 79.39 ? 247 GLU B CD  1 
ATOM   5042  O OE1 . GLU B 1 247 ? 91.691  98.261  162.484 1.00 79.39 ? 247 GLU B OE1 1 
ATOM   5043  O OE2 . GLU B 1 247 ? 89.734  97.285  162.359 1.00 79.39 ? 247 GLU B OE2 1 
ATOM   5044  N N   . PHE B 1 248 ? 93.356  94.382  159.842 1.00 78.50 ? 248 PHE B N   1 
ATOM   5045  C CA  . PHE B 1 248 ? 93.273  93.093  159.165 1.00 78.50 ? 248 PHE B CA  1 
ATOM   5046  C C   . PHE B 1 248 ? 94.620  92.653  158.614 1.00 78.50 ? 248 PHE B C   1 
ATOM   5047  O O   . PHE B 1 248 ? 95.045  91.518  158.845 1.00 78.50 ? 248 PHE B O   1 
ATOM   5048  C CB  . PHE B 1 248 ? 92.262  93.107  158.029 1.00 78.50 ? 248 PHE B CB  1 
ATOM   5049  C CG  . PHE B 1 248 ? 92.334  91.874  157.173 1.00 78.50 ? 248 PHE B CG  1 
ATOM   5050  C CD1 . PHE B 1 248 ? 91.925  90.653  157.669 1.00 78.50 ? 248 PHE B CD1 1 
ATOM   5051  C CD2 . PHE B 1 248 ? 92.857  91.924  155.896 1.00 78.50 ? 248 PHE B CD2 1 
ATOM   5052  C CE1 . PHE B 1 248 ? 91.991  89.528  156.896 1.00 78.50 ? 248 PHE B CE1 1 
ATOM   5053  C CE2 . PHE B 1 248 ? 92.932  90.793  155.123 1.00 78.50 ? 248 PHE B CE2 1 
ATOM   5054  C CZ  . PHE B 1 248 ? 92.500  89.595  155.624 1.00 78.50 ? 248 PHE B CZ  1 
ATOM   5055  N N   . MET B 1 249 ? 95.295  93.520  157.868 1.00 77.65 ? 249 MET B N   1 
ATOM   5056  C CA  . MET B 1 249 ? 96.559  93.156  157.255 1.00 77.65 ? 249 MET B CA  1 
ATOM   5057  C C   . MET B 1 249 ? 97.668  92.948  158.270 1.00 77.65 ? 249 MET B C   1 
ATOM   5058  O O   . MET B 1 249 ? 98.718  92.413  157.906 1.00 77.65 ? 249 MET B O   1 
ATOM   5059  C CB  . MET B 1 249 ? 96.988  94.229  156.259 1.00 77.65 ? 249 MET B CB  1 
ATOM   5060  C CG  . MET B 1 249 ? 96.194  94.245  154.974 1.00 77.65 ? 249 MET B CG  1 
ATOM   5061  S SD  . MET B 1 249 ? 96.693  95.607  153.906 1.00 77.65 ? 249 MET B SD  1 
ATOM   5062  C CE  . MET B 1 249 ? 98.450  95.314  153.729 1.00 77.65 ? 249 MET B CE  1 
ATOM   5063  N N   . SER B 1 250 ? 97.307  93.180  159.522 1.00 81.35 ? 250 SER B N   1 
ATOM   5064  C CA  . SER B 1 250 ? 98.260  92.987  160.592 1.00 81.35 ? 250 SER B CA  1 
ATOM   5065  C C   . SER B 1 250 ? 97.945  91.795  161.465 1.00 81.35 ? 250 SER B C   1 
ATOM   5066  O O   . SER B 1 250 ? 98.446  91.727  162.577 1.00 81.35 ? 250 SER B O   1 
ATOM   5067  C CB  . SER B 1 250 ? 98.363  94.242  161.440 1.00 81.35 ? 250 SER B CB  1 
ATOM   5068  O OG  . SER B 1 250 ? 98.917  95.307  160.693 1.00 81.35 ? 250 SER B OG  1 
ATOM   5069  N N   . GLU B 1 251 ? 97.119  90.866  161.003 1.00 84.60 ? 251 GLU B N   1 
ATOM   5070  C CA  . GLU B 1 251 ? 96.880  89.631  161.735 1.00 84.60 ? 251 GLU B CA  1 
ATOM   5071  C C   . GLU B 1 251 ? 97.969  88.660  161.322 1.00 84.60 ? 251 GLU B C   1 
ATOM   5072  O O   . GLU B 1 251 ? 98.976  89.052  160.732 1.00 84.60 ? 251 GLU B O   1 
ATOM   5073  C CB  . GLU B 1 251 ? 95.562  89.030  161.401 1.00 84.60 ? 251 GLU B CB  1 
ATOM   5074  C CG  . GLU B 1 251 ? 94.405  89.959  161.598 1.00 84.60 ? 251 GLU B CG  1 
ATOM   5075  C CD  . GLU B 1 251 ? 93.267  89.575  160.700 1.00 84.60 ? 251 GLU B CD  1 
ATOM   5076  O OE1 . GLU B 1 251 ? 93.426  88.619  159.919 1.00 84.60 ? 251 GLU B OE1 1 
ATOM   5077  O OE2 . GLU B 1 251 ? 92.225  90.233  160.768 1.00 84.60 ? 251 GLU B OE2 1 
ATOM   5078  N N   . GLU B 1 252 ? 97.799  87.388  161.658 1.00 87.74 ? 252 GLU B N   1 
ATOM   5079  C CA  . GLU B 1 252 ? 98.806  86.398  161.314 1.00 87.74 ? 252 GLU B CA  1 
ATOM   5080  C C   . GLU B 1 252 ? 98.294  85.355  160.338 1.00 87.74 ? 252 GLU B C   1 
ATOM   5081  O O   . GLU B 1 252 ? 99.053  84.856  159.516 1.00 87.74 ? 252 GLU B O   1 
ATOM   5082  C CB  . GLU B 1 252 ? 99.371  85.758  162.573 1.00 87.74 ? 252 GLU B CB  1 
ATOM   5083  C CG  . GLU B 1 252 ? 98.606  84.569  163.133 1.00 87.74 ? 252 GLU B CG  1 
ATOM   5084  C CD  . GLU B 1 252 ? 97.244  84.935  163.678 1.00 87.74 ? 252 GLU B CD  1 
ATOM   5085  O OE1 . GLU B 1 252 ? 97.052  86.097  164.093 1.00 87.74 ? 252 GLU B OE1 1 
ATOM   5086  O OE2 . GLU B 1 252 ? 96.364  84.051  163.694 1.00 87.74 ? 252 GLU B OE2 1 
ATOM   5087  N N   . LYS B 1 253 ? 97.018  85.021  160.425 1.00 88.58 ? 253 LYS B N   1 
ATOM   5088  C CA  . LYS B 1 253 ? 96.430  84.087  159.474 1.00 88.58 ? 253 LYS B CA  1 
ATOM   5089  C C   . LYS B 1 253 ? 96.380  84.697  158.084 1.00 88.58 ? 253 LYS B C   1 
ATOM   5090  O O   . LYS B 1 253 ? 96.558  83.998  157.081 1.00 88.58 ? 253 LYS B O   1 
ATOM   5091  C CB  . LYS B 1 253 ? 95.038  83.672  159.945 1.00 88.58 ? 253 LYS B CB  1 
ATOM   5092  C CG  . LYS B 1 253 ? 94.570  82.342  159.392 1.00 88.58 ? 253 LYS B CG  1 
ATOM   5093  C CD  . LYS B 1 253 ? 93.122  82.072  159.759 1.00 88.58 ? 253 LYS B CD  1 
ATOM   5094  C CE  . LYS B 1 253 ? 92.189  83.097  159.135 1.00 88.58 ? 253 LYS B CE  1 
ATOM   5095  N NZ  . LYS B 1 253 ? 92.287  83.123  157.652 1.00 88.58 ? 253 LYS B NZ  1 
ATOM   5096  N N   . THR B 1 254 ? 96.128  86.001  158.005 1.00 84.33 ? 254 THR B N   1 
ATOM   5097  C CA  . THR B 1 254 ? 96.291  86.706  156.741 1.00 84.33 ? 254 THR B CA  1 
ATOM   5098  C C   . THR B 1 254 ? 97.726  86.608  156.254 1.00 84.33 ? 254 THR B C   1 
ATOM   5099  O O   . THR B 1 254 ? 97.991  86.118  155.153 1.00 84.33 ? 254 THR B O   1 
ATOM   5100  C CB  . THR B 1 254 ? 95.893  88.167  156.909 1.00 84.33 ? 254 THR B CB  1 
ATOM   5101  O OG1 . THR B 1 254 ? 94.585  88.239  157.484 1.00 84.33 ? 254 THR B OG1 1 
ATOM   5102  C CG2 . THR B 1 254 ? 95.899  88.876  155.571 1.00 84.33 ? 254 THR B CG2 1 
ATOM   5103  N N   . HIS B 1 255 ? 98.671  87.045  157.080 1.00 83.26 ? 255 HIS B N   1 
ATOM   5104  C CA  . HIS B 1 255 ? 100.060 87.120  156.660 1.00 83.26 ? 255 HIS B CA  1 
ATOM   5105  C C   . HIS B 1 255 ? 100.669 85.761  156.355 1.00 83.26 ? 255 HIS B C   1 
ATOM   5106  O O   . HIS B 1 255 ? 101.783 85.710  155.826 1.00 83.26 ? 255 HIS B O   1 
ATOM   5107  C CB  . HIS B 1 255 ? 100.886 87.828  157.729 1.00 83.26 ? 255 HIS B CB  1 
ATOM   5108  C CG  . HIS B 1 255 ? 102.156 88.418  157.210 1.00 83.26 ? 255 HIS B CG  1 
ATOM   5109  N ND1 . HIS B 1 255 ? 103.151 87.654  156.642 1.00 83.26 ? 255 HIS B ND1 1 
ATOM   5110  C CD2 . HIS B 1 255 ? 102.594 89.698  157.171 1.00 83.26 ? 255 HIS B CD2 1 
ATOM   5111  C CE1 . HIS B 1 255 ? 104.149 88.437  156.276 1.00 83.26 ? 255 HIS B CE1 1 
ATOM   5112  N NE2 . HIS B 1 255 ? 103.837 89.682  156.587 1.00 83.26 ? 255 HIS B NE2 1 
ATOM   5113  N N   . GLU B 1 256 ? 99.981  84.663  156.670 1.00 86.41 ? 256 GLU B N   1 
ATOM   5114  C CA  . GLU B 1 256 ? 100.521 83.363  156.287 1.00 86.41 ? 256 GLU B CA  1 
ATOM   5115  C C   . GLU B 1 256 ? 100.208 83.009  154.836 1.00 86.41 ? 256 GLU B C   1 
ATOM   5116  O O   . GLU B 1 256 ? 101.009 82.324  154.190 1.00 86.41 ? 256 GLU B O   1 
ATOM   5117  C CB  . GLU B 1 256 ? 100.000 82.268  157.223 1.00 86.41 ? 256 GLU B CB  1 
ATOM   5118  C CG  . GLU B 1 256 ? 98.651  81.691  156.854 1.00 86.41 ? 256 GLU B CG  1 
ATOM   5119  C CD  . GLU B 1 256 ? 98.074  80.807  157.942 1.00 86.41 ? 256 GLU B CD  1 
ATOM   5120  O OE1 . GLU B 1 256 ? 98.019  81.253  159.106 1.00 86.41 ? 256 GLU B OE1 1 
ATOM   5121  O OE2 . GLU B 1 256 ? 97.674  79.666  157.633 1.00 86.41 ? 256 GLU B OE2 1 
ATOM   5122  N N   . THR B 1 257 ? 99.076  83.473  154.301 1.00 84.26 ? 257 THR B N   1 
ATOM   5123  C CA  . THR B 1 257 ? 98.617  83.082  152.971 1.00 84.26 ? 257 THR B CA  1 
ATOM   5124  C C   . THR B 1 257 ? 98.960  84.100  151.888 1.00 84.26 ? 257 THR B C   1 
ATOM   5125  O O   . THR B 1 257 ? 99.338  83.714  150.780 1.00 84.26 ? 257 THR B O   1 
ATOM   5126  C CB  . THR B 1 257 ? 97.106  82.816  152.999 1.00 84.26 ? 257 THR B CB  1 
ATOM   5127  O OG1 . THR B 1 257 ? 96.652  82.440  151.695 1.00 84.26 ? 257 THR B OG1 1 
ATOM   5128  C CG2 . THR B 1 257 ? 96.333  84.024  153.486 1.00 84.26 ? 257 THR B CG2 1 
ATOM   5129  N N   . MET B 1 258 ? 98.847  85.390  152.181 1.00 81.11 ? 258 MET B N   1 
ATOM   5130  C CA  . MET B 1 258 ? 99.269  86.412  151.238 1.00 81.11 ? 258 MET B CA  1 
ATOM   5131  C C   . MET B 1 258 ? 100.779 86.555  151.258 1.00 81.11 ? 258 MET B C   1 
ATOM   5132  O O   . MET B 1 258 ? 101.466 85.951  152.082 1.00 81.11 ? 258 MET B O   1 
ATOM   5133  C CB  . MET B 1 258 ? 98.625  87.744  151.589 1.00 81.11 ? 258 MET B CB  1 
ATOM   5134  C CG  . MET B 1 258 ? 98.893  88.145  153.013 1.00 81.11 ? 258 MET B CG  1 
ATOM   5135  S SD  . MET B 1 258 ? 100.169 89.379  153.239 1.00 81.11 ? 258 MET B SD  1 
ATOM   5136  C CE  . MET B 1 258 ? 99.201  90.860  152.996 1.00 81.11 ? 258 MET B CE  1 
ATOM   5137  N N   . MET B 1 259 ? 101.305 87.355  150.338 1.00 76.78 ? 259 MET B N   1 
ATOM   5138  C CA  . MET B 1 259 ? 102.667 87.854  150.482 1.00 76.78 ? 259 MET B CA  1 
ATOM   5139  C C   . MET B 1 259 ? 102.594 89.371  150.467 1.00 76.78 ? 259 MET B C   1 
ATOM   5140  O O   . MET B 1 259 ? 102.242 89.975  149.453 1.00 76.78 ? 259 MET B O   1 
ATOM   5141  C CB  . MET B 1 259 ? 103.621 87.302  149.418 1.00 76.78 ? 259 MET B CB  1 
ATOM   5142  C CG  . MET B 1 259 ? 103.364 87.691  147.976 1.00 76.78 ? 259 MET B CG  1 
ATOM   5143  S SD  . MET B 1 259 ? 101.957 86.803  147.296 1.00 76.78 ? 259 MET B SD  1 
ATOM   5144  C CE  . MET B 1 259 ? 102.654 85.162  147.197 1.00 76.78 ? 259 MET B CE  1 
ATOM   5145  N N   . VAL B 1 260 ? 102.896 89.984  151.610 1.00 74.48 ? 260 VAL B N   1 
ATOM   5146  C CA  . VAL B 1 260 ? 102.648 91.405  151.756 1.00 74.48 ? 260 VAL B CA  1 
ATOM   5147  C C   . VAL B 1 260 ? 103.599 92.241  150.917 1.00 74.48 ? 260 VAL B C   1 
ATOM   5148  O O   . VAL B 1 260 ? 103.310 93.412  150.651 1.00 74.48 ? 260 VAL B O   1 
ATOM   5149  C CB  . VAL B 1 260 ? 102.724 91.789  153.242 1.00 74.48 ? 260 VAL B CB  1 
ATOM   5150  C CG1 . VAL B 1 260 ? 104.148 91.727  153.730 1.00 74.48 ? 260 VAL B CG1 1 
ATOM   5151  C CG2 . VAL B 1 260 ? 102.091 93.137  153.490 1.00 74.48 ? 260 VAL B CG2 1 
ATOM   5152  N N   . ASP B 1 261 ? 104.709 91.677  150.460 1.00 73.85 ? 261 ASP B N   1 
ATOM   5153  C CA  . ASP B 1 261 ? 105.677 92.491  149.744 1.00 73.85 ? 261 ASP B CA  1 
ATOM   5154  C C   . ASP B 1 261 ? 105.361 92.658  148.264 1.00 73.85 ? 261 ASP B C   1 
ATOM   5155  O O   . ASP B 1 261 ? 106.134 93.305  147.551 1.00 73.85 ? 261 ASP B O   1 
ATOM   5156  C CB  . ASP B 1 261 ? 107.073 91.916  149.940 1.00 73.85 ? 261 ASP B CB  1 
ATOM   5157  C CG  . ASP B 1 261 ? 107.589 92.149  151.342 1.00 73.85 ? 261 ASP B CG  1 
ATOM   5158  O OD1 . ASP B 1 261 ? 106.762 92.444  152.228 1.00 73.85 ? 261 ASP B OD1 1 
ATOM   5159  O OD2 . ASP B 1 261 ? 108.813 92.059  151.561 1.00 73.85 ? 261 ASP B OD2 1 
ATOM   5160  N N   . ARG B 1 262 ? 104.264 92.097  147.773 1.00 72.72 ? 262 ARG B N   1 
ATOM   5161  C CA  . ARG B 1 262 ? 103.721 92.504  146.479 1.00 72.72 ? 262 ARG B CA  1 
ATOM   5162  C C   . ARG B 1 262 ? 102.554 93.458  146.717 1.00 72.72 ? 262 ARG B C   1 
ATOM   5163  O O   . ARG B 1 262 ? 101.408 93.197  146.361 1.00 72.72 ? 262 ARG B O   1 
ATOM   5164  C CB  . ARG B 1 262 ? 103.292 91.287  145.664 1.00 72.72 ? 262 ARG B CB  1 
ATOM   5165  C CG  . ARG B 1 262 ? 104.428 90.374  145.239 1.00 72.72 ? 262 ARG B CG  1 
ATOM   5166  C CD  . ARG B 1 262 ? 105.313 91.010  144.183 1.00 72.72 ? 262 ARG B CD  1 
ATOM   5167  N NE  . ARG B 1 262 ? 106.461 91.700  144.768 1.00 72.72 ? 262 ARG B NE  1 
ATOM   5168  C CZ  . ARG B 1 262 ? 107.435 92.270  144.064 1.00 72.72 ? 262 ARG B CZ  1 
ATOM   5169  N NH1 . ARG B 1 262 ? 107.412 92.233  142.738 1.00 72.72 ? 262 ARG B NH1 1 
ATOM   5170  N NH2 . ARG B 1 262 ? 108.436 92.875  144.684 1.00 72.72 ? 262 ARG B NH2 1 
ATOM   5171  N N   . SER B 1 263 ? 102.871 94.584  147.345 1.00 66.22 ? 263 SER B N   1 
ATOM   5172  C CA  . SER B 1 263 ? 101.845 95.529  147.750 1.00 66.22 ? 263 SER B CA  1 
ATOM   5173  C C   . SER B 1 263 ? 102.208 96.936  147.312 1.00 66.22 ? 263 SER B C   1 
ATOM   5174  O O   . SER B 1 263 ? 103.384 97.290  147.203 1.00 66.22 ? 263 SER B O   1 
ATOM   5175  C CB  . SER B 1 263 ? 101.629 95.516  149.260 1.00 66.22 ? 263 SER B CB  1 
ATOM   5176  O OG  . SER B 1 263 ? 101.384 94.204  149.719 1.00 66.22 ? 263 SER B OG  1 
ATOM   5177  N N   . TYR B 1 264 ? 101.178 97.737  147.066 1.00 61.30 ? 264 TYR B N   1 
ATOM   5178  C CA  . TYR B 1 264 ? 101.366 99.153  146.819 1.00 61.30 ? 264 TYR B CA  1 
ATOM   5179  C C   . TYR B 1 264 ? 100.123 99.885  147.287 1.00 61.30 ? 264 TYR B C   1 
ATOM   5180  O O   . TYR B 1 264 ? 99.112  99.273  147.631 1.00 61.30 ? 264 TYR B O   1 
ATOM   5181  C CB  . TYR B 1 264 ? 101.680 99.435  145.340 1.00 61.30 ? 264 TYR B CB  1 
ATOM   5182  C CG  . TYR B 1 264 ? 100.588 99.190  144.308 1.00 61.30 ? 264 TYR B CG  1 
ATOM   5183  C CD1 . TYR B 1 264 ? 99.427  99.947  144.288 1.00 61.30 ? 264 TYR B CD1 1 
ATOM   5184  C CD2 . TYR B 1 264 ? 100.752 98.241  143.316 1.00 61.30 ? 264 TYR B CD2 1 
ATOM   5185  C CE1 . TYR B 1 264 ? 98.453  99.740  143.345 1.00 61.30 ? 264 TYR B CE1 1 
ATOM   5186  C CE2 . TYR B 1 264 ? 99.782  98.037  142.362 1.00 61.30 ? 264 TYR B CE2 1 
ATOM   5187  C CZ  . TYR B 1 264 ? 98.634  98.786  142.386 1.00 61.30 ? 264 TYR B CZ  1 
ATOM   5188  O OH  . TYR B 1 264 ? 97.661  98.582  141.440 1.00 61.30 ? 264 TYR B OH  1 
ATOM   5189  N N   . LEU B 1 265 ? 100.208 101.210 147.309 1.00 60.42 ? 265 LEU B N   1 
ATOM   5190  C CA  . LEU B 1 265 ? 99.022  102.037 147.460 1.00 60.42 ? 265 LEU B CA  1 
ATOM   5191  C C   . LEU B 1 265 ? 99.046  103.120 146.402 1.00 60.42 ? 265 LEU B C   1 
ATOM   5192  O O   . LEU B 1 265 ? 100.118 103.558 145.985 1.00 60.42 ? 265 LEU B O   1 
ATOM   5193  C CB  . LEU B 1 265 ? 98.908  102.663 148.844 1.00 60.42 ? 265 LEU B CB  1 
ATOM   5194  C CG  . LEU B 1 265 ? 99.801  103.801 149.323 1.00 60.42 ? 265 LEU B CG  1 
ATOM   5195  C CD1 . LEU B 1 265 ? 99.211  105.151 148.947 1.00 60.42 ? 265 LEU B CD1 1 
ATOM   5196  C CD2 . LEU B 1 265 ? 99.950  103.698 150.821 1.00 60.42 ? 265 LEU B CD2 1 
ATOM   5197  N N   . SER B 1 266 ? 97.873  103.569 145.987 1.00 59.64 ? 266 SER B N   1 
ATOM   5198  C CA  . SER B 1 266 ? 97.763  104.383 144.792 1.00 59.64 ? 266 SER B CA  1 
ATOM   5199  C C   . SER B 1 266 ? 96.853  105.578 145.028 1.00 59.64 ? 266 SER B C   1 
ATOM   5200  O O   . SER B 1 266 ? 96.145  105.667 146.033 1.00 59.64 ? 266 SER B O   1 
ATOM   5201  C CB  . SER B 1 266 ? 97.249  103.544 143.626 1.00 59.64 ? 266 SER B CB  1 
ATOM   5202  O OG  . SER B 1 266 ? 95.970  103.019 143.915 1.00 59.64 ? 266 SER B OG  1 
ATOM   5203  N N   . PHE B 1 267 ? 96.888  106.499 144.071 1.00 53.25 ? 267 PHE B N   1 
ATOM   5204  C CA  . PHE B 1 267 ? 96.165  107.756 144.172 1.00 53.25 ? 267 PHE B CA  1 
ATOM   5205  C C   . PHE B 1 267 ? 96.137  108.406 142.801 1.00 53.25 ? 267 PHE B C   1 
ATOM   5206  O O   . PHE B 1 267 ? 97.000  108.157 141.955 1.00 53.25 ? 267 PHE B O   1 
ATOM   5207  C CB  . PHE B 1 267 ? 96.823  108.696 145.179 1.00 53.25 ? 267 PHE B CB  1 
ATOM   5208  C CG  . PHE B 1 267 ? 98.232  109.059 144.821 1.00 53.25 ? 267 PHE B CG  1 
ATOM   5209  C CD1 . PHE B 1 267 ? 99.281  108.295 145.259 1.00 53.25 ? 267 PHE B CD1 1 
ATOM   5210  C CD2 . PHE B 1 267 ? 98.501  110.150 144.027 1.00 53.25 ? 267 PHE B CD2 1 
ATOM   5211  C CE1 . PHE B 1 267 ? 100.562 108.615 144.924 1.00 53.25 ? 267 PHE B CE1 1 
ATOM   5212  C CE2 . PHE B 1 267 ? 99.784  110.465 143.691 1.00 53.25 ? 267 PHE B CE2 1 
ATOM   5213  C CZ  . PHE B 1 267 ? 100.816 109.697 144.141 1.00 53.25 ? 267 PHE B CZ  1 
ATOM   5214  N N   . ASP B 1 268 ? 95.163  109.282 142.610 1.00 58.12 ? 268 ASP B N   1 
ATOM   5215  C CA  . ASP B 1 268 ? 95.029  110.030 141.375 1.00 58.12 ? 268 ASP B CA  1 
ATOM   5216  C C   . ASP B 1 268 ? 95.697  111.390 141.510 1.00 58.12 ? 268 ASP B C   1 
ATOM   5217  O O   . ASP B 1 268 ? 95.507  112.088 142.509 1.00 58.12 ? 268 ASP B O   1 
ATOM   5218  C CB  . ASP B 1 268 ? 93.560  110.210 141.023 1.00 58.12 ? 268 ASP B CB  1 
ATOM   5219  C CG  . ASP B 1 268 ? 92.880  108.907 140.757 1.00 58.12 ? 268 ASP B CG  1 
ATOM   5220  O OD1 . ASP B 1 268 ? 93.568  107.962 140.337 1.00 58.12 ? 268 ASP B OD1 1 
ATOM   5221  O OD2 . ASP B 1 268 ? 91.659  108.816 140.968 1.00 58.12 ? 268 ASP B OD2 1 
ATOM   5222  N N   . CYS B 1 269 ? 96.475  111.763 140.497 1.00 55.90 ? 269 CYS B N   1 
ATOM   5223  C CA  . CYS B 1 269 ? 97.074  113.094 140.425 1.00 55.90 ? 269 CYS B CA  1 
ATOM   5224  C C   . CYS B 1 269 ? 95.980  114.074 140.028 1.00 55.90 ? 269 CYS B C   1 
ATOM   5225  O O   . CYS B 1 269 ? 95.802  114.412 138.860 1.00 55.90 ? 269 CYS B O   1 
ATOM   5226  C CB  . CYS B 1 269 ? 98.235  113.110 139.443 1.00 55.90 ? 269 CYS B CB  1 
ATOM   5227  S SG  . CYS B 1 269 ? 99.568  111.988 139.881 1.00 55.90 ? 269 CYS B SG  1 
ATOM   5228  N N   . LEU B 1 270 ? 95.230  114.529 141.023 1.00 62.01 ? 270 LEU B N   1 
ATOM   5229  C CA  . LEU B 1 270 ? 94.078  115.384 140.803 1.00 62.01 ? 270 LEU B CA  1 
ATOM   5230  C C   . LEU B 1 270 ? 93.914  116.289 142.014 1.00 62.01 ? 270 LEU B C   1 
ATOM   5231  O O   . LEU B 1 270 ? 94.811  116.402 142.853 1.00 62.01 ? 270 LEU B O   1 
ATOM   5232  C CB  . LEU B 1 270 ? 92.819  114.546 140.564 1.00 62.01 ? 270 LEU B CB  1 
ATOM   5233  C CG  . LEU B 1 270 ? 92.560  114.044 139.149 1.00 62.01 ? 270 LEU B CG  1 
ATOM   5234  C CD1 . LEU B 1 270 ? 91.220  113.348 139.093 1.00 62.01 ? 270 LEU B CD1 1 
ATOM   5235  C CD2 . LEU B 1 270 ? 92.608  115.195 138.172 1.00 62.01 ? 270 LEU B CD2 1 
ATOM   5236  N N   . ASP B 1 271 ? 92.765  116.940 142.097 1.00 68.80 ? 271 ASP B N   1 
ATOM   5237  C CA  . ASP B 1 271 ? 92.399  117.720 143.268 1.00 68.80 ? 271 ASP B CA  1 
ATOM   5238  C C   . ASP B 1 271 ? 92.247  116.774 144.448 1.00 68.80 ? 271 ASP B C   1 
ATOM   5239  O O   . ASP B 1 271 ? 91.296  115.985 144.484 1.00 68.80 ? 271 ASP B O   1 
ATOM   5240  C CB  . ASP B 1 271 ? 91.102  118.487 143.014 1.00 68.80 ? 271 ASP B CB  1 
ATOM   5241  C CG  . ASP B 1 271 ? 90.841  119.553 144.053 1.00 68.80 ? 271 ASP B CG  1 
ATOM   5242  O OD1 . ASP B 1 271 ? 91.589  119.617 145.047 1.00 68.80 ? 271 ASP B OD1 1 
ATOM   5243  O OD2 . ASP B 1 271 ? 89.887  120.335 143.874 1.00 68.80 ? 271 ASP B OD2 1 
ATOM   5244  N N   . PRO B 1 272 ? 93.149  116.821 145.432 1.00 68.45 ? 272 PRO B N   1 
ATOM   5245  C CA  . PRO B 1 272 ? 93.111  115.827 146.515 1.00 68.45 ? 272 PRO B CA  1 
ATOM   5246  C C   . PRO B 1 272 ? 91.789  115.771 147.238 1.00 68.45 ? 272 PRO B C   1 
ATOM   5247  O O   . PRO B 1 272 ? 91.564  114.825 147.997 1.00 68.45 ? 272 PRO B O   1 
ATOM   5248  C CB  . PRO B 1 272 ? 94.241  116.272 147.450 1.00 68.45 ? 272 PRO B CB  1 
ATOM   5249  C CG  . PRO B 1 272 ? 94.528  117.661 147.076 1.00 68.45 ? 272 PRO B CG  1 
ATOM   5250  C CD  . PRO B 1 272 ? 94.235  117.789 145.624 1.00 68.45 ? 272 PRO B CD  1 
ATOM   5251  N N   . ALA B 1 273 ? 90.904  116.740 147.018 1.00 70.76 ? 273 ALA B N   1 
ATOM   5252  C CA  . ALA B 1 273 ? 89.526  116.601 147.462 1.00 70.76 ? 273 ALA B CA  1 
ATOM   5253  C C   . ALA B 1 273 ? 88.727  115.677 146.551 1.00 70.76 ? 273 ALA B C   1 
ATOM   5254  O O   . ALA B 1 273 ? 87.558  115.401 146.837 1.00 70.76 ? 273 ALA B O   1 
ATOM   5255  C CB  . ALA B 1 273 ? 88.860  117.972 147.537 1.00 70.76 ? 273 ALA B CB  1 
ATOM   5256  N N   . LYS B 1 274 ? 89.329  115.195 145.466 1.00 70.76 ? 274 LYS B N   1 
ATOM   5257  C CA  . LYS B 1 274 ? 88.647  114.302 144.544 1.00 70.76 ? 274 LYS B CA  1 
ATOM   5258  C C   . LYS B 1 274 ? 89.323  112.947 144.406 1.00 70.76 ? 274 LYS B C   1 
ATOM   5259  O O   . LYS B 1 274 ? 88.675  111.992 143.966 1.00 70.76 ? 274 LYS B O   1 
ATOM   5260  C CB  . LYS B 1 274 ? 88.552  114.948 143.160 1.00 70.76 ? 274 LYS B CB  1 
ATOM   5261  C CG  . LYS B 1 274 ? 88.000  116.350 143.179 1.00 70.76 ? 274 LYS B CG  1 
ATOM   5262  C CD  . LYS B 1 274 ? 86.512  116.336 143.429 1.00 70.76 ? 274 LYS B CD  1 
ATOM   5263  C CE  . LYS B 1 274 ? 85.992  117.734 143.693 1.00 70.76 ? 274 LYS B CE  1 
ATOM   5264  N NZ  . LYS B 1 274 ? 86.518  118.287 144.970 1.00 70.76 ? 274 LYS B NZ  1 
ATOM   5265  N N   . SER B 1 275 ? 90.599  112.839 144.765 1.00 67.78 ? 275 SER B N   1 
ATOM   5266  C CA  . SER B 1 275 ? 91.325  111.593 144.593 1.00 67.78 ? 275 SER B CA  1 
ATOM   5267  C C   . SER B 1 275 ? 90.858  110.552 145.611 1.00 67.78 ? 275 SER B C   1 
ATOM   5268  O O   . SER B 1 275 ? 89.972  110.788 146.436 1.00 67.78 ? 275 SER B O   1 
ATOM   5269  C CB  . SER B 1 275 ? 92.823  111.833 144.724 1.00 67.78 ? 275 SER B CB  1 
ATOM   5270  O OG  . SER B 1 275 ? 93.288  112.736 143.744 1.00 67.78 ? 275 SER B OG  1 
ATOM   5271  N N   . ARG B 1 276 ? 91.472  109.376 145.538 1.00 66.77 ? 276 ARG B N   1 
ATOM   5272  C CA  . ARG B 1 276 ? 91.231  108.280 146.459 1.00 66.77 ? 276 ARG B CA  1 
ATOM   5273  C C   . ARG B 1 276 ? 92.572  107.726 146.904 1.00 66.77 ? 276 ARG B C   1 
ATOM   5274  O O   . ARG B 1 276 ? 93.621  108.088 146.370 1.00 66.77 ? 276 ARG B O   1 
ATOM   5275  C CB  . ARG B 1 276 ? 90.391  107.174 145.813 1.00 66.77 ? 276 ARG B CB  1 
ATOM   5276  C CG  . ARG B 1 276 ? 88.989  107.595 145.450 1.00 66.77 ? 276 ARG B CG  1 
ATOM   5277  C CD  . ARG B 1 276 ? 88.909  108.038 144.012 1.00 66.77 ? 276 ARG B CD  1 
ATOM   5278  N NE  . ARG B 1 276 ? 89.383  107.004 143.100 1.00 66.77 ? 276 ARG B NE  1 
ATOM   5279  C CZ  . ARG B 1 276 ? 88.642  105.986 142.676 1.00 66.77 ? 276 ARG B CZ  1 
ATOM   5280  N NH1 . ARG B 1 276 ? 87.389  105.861 143.087 1.00 66.77 ? 276 ARG B NH1 1 
ATOM   5281  N NH2 . ARG B 1 276 ? 89.155  105.088 141.846 1.00 66.77 ? 276 ARG B NH2 1 
ATOM   5282  N N   . ILE B 1 277 ? 92.547  106.839 147.890 1.00 66.79 ? 277 ILE B N   1 
ATOM   5283  C CA  . ILE B 1 277 ? 93.757  106.128 148.280 1.00 66.79 ? 277 ILE B CA  1 
ATOM   5284  C C   . ILE B 1 277 ? 93.446  104.642 148.285 1.00 66.79 ? 277 ILE B C   1 
ATOM   5285  O O   . ILE B 1 277 ? 92.661  104.176 149.113 1.00 66.79 ? 277 ILE B O   1 
ATOM   5286  C CB  . ILE B 1 277 ? 94.285  106.574 149.649 1.00 66.79 ? 277 ILE B CB  1 
ATOM   5287  C CG1 . ILE B 1 277 ? 94.801  108.003 149.578 1.00 66.79 ? 277 ILE B CG1 1 
ATOM   5288  C CG2 . ILE B 1 277 ? 95.435  105.688 150.064 1.00 66.79 ? 277 ILE B CG2 1 
ATOM   5289  C CD1 . ILE B 1 277 ? 96.185  108.089 149.019 1.00 66.79 ? 277 ILE B CD1 1 
ATOM   5290  N N   . LYS B 1 278 ? 94.059  103.902 147.370 1.00 65.71 ? 278 LYS B N   1 
ATOM   5291  C CA  . LYS B 1 278 ? 93.807  102.478 147.218 1.00 65.71 ? 278 LYS B CA  1 
ATOM   5292  C C   . LYS B 1 278 ? 95.012  101.700 147.712 1.00 65.71 ? 278 LYS B C   1 
ATOM   5293  O O   . LYS B 1 278 ? 96.134  101.973 147.288 1.00 65.71 ? 278 LYS B O   1 
ATOM   5294  C CB  . LYS B 1 278 ? 93.527  102.123 145.759 1.00 65.71 ? 278 LYS B CB  1 
ATOM   5295  C CG  . LYS B 1 278 ? 92.600  103.080 145.045 1.00 65.71 ? 278 LYS B CG  1 
ATOM   5296  C CD  . LYS B 1 278 ? 92.067  102.490 143.749 1.00 65.71 ? 278 LYS B CD  1 
ATOM   5297  C CE  . LYS B 1 278 ? 93.145  102.419 142.681 1.00 65.71 ? 278 LYS B CE  1 
ATOM   5298  N NZ  . LYS B 1 278 ? 92.631  101.886 141.392 1.00 65.71 ? 278 LYS B NZ  1 
ATOM   5299  N N   . ILE B 1 279 ? 94.776  100.743 148.601 1.00 66.71 ? 279 ILE B N   1 
ATOM   5300  C CA  . ILE B 1 279 ? 95.781  99.770  149.012 1.00 66.71 ? 279 ILE B CA  1 
ATOM   5301  C C   . ILE B 1 279 ? 95.629  98.542  148.131 1.00 66.71 ? 279 ILE B C   1 
ATOM   5302  O O   . ILE B 1 279 ? 94.542  98.252  147.634 1.00 66.71 ? 279 ILE B O   1 
ATOM   5303  C CB  . ILE B 1 279 ? 95.648  99.405  150.503 1.00 66.71 ? 279 ILE B CB  1 
ATOM   5304  C CG1 . ILE B 1 279 ? 95.515  100.663 151.353 1.00 66.71 ? 279 ILE B CG1 1 
ATOM   5305  C CG2 . ILE B 1 279 ? 96.865  98.645  150.962 1.00 66.71 ? 279 ILE B CG2 1 
ATOM   5306  C CD1 . ILE B 1 279 ? 96.744  101.516 151.353 1.00 66.71 ? 279 ILE B CD1 1 
ATOM   5307  N N   . TYR B 1 280 ? 96.720  97.810  147.935 1.00 67.68 ? 280 TYR B N   1 
ATOM   5308  C CA  . TYR B 1 280 ? 96.746  96.741  146.947 1.00 67.68 ? 280 TYR B CA  1 
ATOM   5309  C C   . TYR B 1 280 ? 97.787  95.704  147.329 1.00 67.68 ? 280 TYR B C   1 
ATOM   5310  O O   . TYR B 1 280 ? 98.949  96.060  147.529 1.00 67.68 ? 280 TYR B O   1 
ATOM   5311  C CB  . TYR B 1 280 ? 97.062  97.318  145.572 1.00 67.68 ? 280 TYR B CB  1 
ATOM   5312  C CG  . TYR B 1 280 ? 97.337  96.289  144.519 1.00 67.68 ? 280 TYR B CG  1 
ATOM   5313  C CD1 . TYR B 1 280 ? 98.603  95.744  144.371 1.00 67.68 ? 280 TYR B CD1 1 
ATOM   5314  C CD2 . TYR B 1 280 ? 96.338  95.866  143.663 1.00 67.68 ? 280 TYR B CD2 1 
ATOM   5315  C CE1 . TYR B 1 280 ? 98.863  94.807  143.414 1.00 67.68 ? 280 TYR B CE1 1 
ATOM   5316  C CE2 . TYR B 1 280 ? 96.591  94.926  142.696 1.00 67.68 ? 280 TYR B CE2 1 
ATOM   5317  C CZ  . TYR B 1 280 ? 97.858  94.401  142.581 1.00 67.68 ? 280 TYR B CZ  1 
ATOM   5318  O OH  . TYR B 1 280 ? 98.135  93.462  141.625 1.00 67.68 ? 280 TYR B OH  1 
ATOM   5319  N N   . THR B 1 281 ? 97.387  94.428  147.380 1.00 71.53 ? 281 THR B N   1 
ATOM   5320  C CA  . THR B 1 281 ? 98.299  93.343  147.741 1.00 71.53 ? 281 THR B CA  1 
ATOM   5321  C C   . THR B 1 281 ? 97.878  92.057  147.024 1.00 71.53 ? 281 THR B C   1 
ATOM   5322  O O   . THR B 1 281 ? 96.944  92.055  146.220 1.00 71.53 ? 281 THR B O   1 
ATOM   5323  C CB  . THR B 1 281 ? 98.356  93.173  149.263 1.00 71.53 ? 281 THR B CB  1 
ATOM   5324  O OG1 . THR B 1 281 ? 99.521  92.424  149.624 1.00 71.53 ? 281 THR B OG1 1 
ATOM   5325  C CG2 . THR B 1 281 ? 97.129  92.466  149.763 1.00 71.53 ? 281 THR B CG2 1 
ATOM   5326  N N   . GLU B 1 282 ? 98.593  90.955  147.310 1.00 75.94 ? 282 GLU B N   1 
ATOM   5327  C CA  . GLU B 1 282 ? 98.510  89.718  146.532 1.00 75.94 ? 282 GLU B CA  1 
ATOM   5328  C C   . GLU B 1 282 ? 98.472  88.477  147.419 1.00 75.94 ? 282 GLU B C   1 
ATOM   5329  O O   . GLU B 1 282 ? 99.196  88.390  148.422 1.00 75.94 ? 282 GLU B O   1 
ATOM   5330  C CB  . GLU B 1 282 ? 99.699  89.591  145.571 1.00 75.94 ? 282 GLU B CB  1 
ATOM   5331  C CG  . GLU B 1 282 ? 99.685  90.569  144.415 1.00 75.94 ? 282 GLU B CG  1 
ATOM   5332  C CD  . GLU B 1 282 ? 100.712 90.227  143.358 1.00 75.94 ? 282 GLU B CD  1 
ATOM   5333  O OE1 . GLU B 1 282 ? 101.488 89.275  143.569 1.00 75.94 ? 282 GLU B OE1 1 
ATOM   5334  O OE2 . GLU B 1 282 ? 100.737 90.904  142.311 1.00 75.94 ? 282 GLU B OE2 1 
ATOM   5335  N N   . ALA B 1 283 ? 97.664  87.492  147.006 1.00 78.35 ? 283 ALA B N   1 
ATOM   5336  C CA  . ALA B 1 283 ? 97.442  86.279  147.782 1.00 78.35 ? 283 ALA B CA  1 
ATOM   5337  C C   . ALA B 1 283 ? 97.463  85.047  146.887 1.00 78.35 ? 283 ALA B C   1 
ATOM   5338  O O   . ALA B 1 283 ? 97.073  85.097  145.716 1.00 78.35 ? 283 ALA B O   1 
ATOM   5339  C CB  . ALA B 1 283 ? 96.109  86.327  148.531 1.00 78.35 ? 283 ALA B CB  1 
ATOM   5340  N N   . LYS B 1 284 ? 97.924  83.935  147.462 1.00 78.96 ? 284 LYS B N   1 
ATOM   5341  C CA  . LYS B 1 284 ? 97.929  82.614  146.833 1.00 78.96 ? 284 LYS B CA  1 
ATOM   5342  C C   . LYS B 1 284 ? 97.039  81.725  147.685 1.00 78.96 ? 284 LYS B C   1 
ATOM   5343  O O   . LYS B 1 284 ? 97.505  81.136  148.662 1.00 78.96 ? 284 LYS B O   1 
ATOM   5344  C CB  . LYS B 1 284 ? 99.334  82.036  146.756 1.00 78.96 ? 284 LYS B CB  1 
ATOM   5345  C CG  . LYS B 1 284 ? 100.136 82.437  145.547 1.00 78.96 ? 284 LYS B CG  1 
ATOM   5346  C CD  . LYS B 1 284 ? 101.553 81.927  145.687 1.00 78.96 ? 284 LYS B CD  1 
ATOM   5347  C CE  . LYS B 1 284 ? 102.441 82.442  144.580 1.00 78.96 ? 284 LYS B CE  1 
ATOM   5348  N NZ  . LYS B 1 284 ? 103.854 82.511  145.032 1.00 78.96 ? 284 LYS B NZ  1 
ATOM   5349  N N   . VAL B 1 285 ? 95.771  81.608  147.322 1.00 82.12 ? 285 VAL B N   1 
ATOM   5350  C CA  . VAL B 1 285 ? 94.798  80.997  148.214 1.00 82.12 ? 285 VAL B CA  1 
ATOM   5351  C C   . VAL B 1 285 ? 94.290  79.683  147.643 1.00 82.12 ? 285 VAL B C   1 
ATOM   5352  O O   . VAL B 1 285 ? 94.279  79.458  146.430 1.00 82.12 ? 285 VAL B O   1 
ATOM   5353  C CB  . VAL B 1 285 ? 93.635  81.961  148.504 1.00 82.12 ? 285 VAL B CB  1 
ATOM   5354  C CG1 . VAL B 1 285 ? 94.165  83.208  149.172 1.00 82.12 ? 285 VAL B CG1 1 
ATOM   5355  C CG2 . VAL B 1 285 ? 92.919  82.315  147.221 1.00 82.12 ? 285 VAL B CG2 1 
ATOM   5356  N N   . LYS B 1 286 ? 93.849  78.813  148.548 1.00 82.13 ? 286 LYS B N   1 
ATOM   5357  C CA  . LYS B 1 286 ? 93.399  77.462  148.250 1.00 82.13 ? 286 LYS B CA  1 
ATOM   5358  C C   . LYS B 1 286 ? 91.907  77.374  147.991 1.00 82.13 ? 286 LYS B C   1 
ATOM   5359  O O   . LYS B 1 286 ? 91.487  76.774  147.000 1.00 82.13 ? 286 LYS B O   1 
ATOM   5360  C CB  . LYS B 1 286 ? 93.757  76.537  149.413 1.00 82.13 ? 286 LYS B CB  1 
ATOM   5361  C CG  . LYS B 1 286 ? 93.291  75.110  149.264 1.00 82.13 ? 286 LYS B CG  1 
ATOM   5362  C CD  . LYS B 1 286 ? 94.053  74.386  148.174 1.00 82.13 ? 286 LYS B CD  1 
ATOM   5363  C CE  . LYS B 1 286 ? 93.723  72.902  148.176 1.00 82.13 ? 286 LYS B CE  1 
ATOM   5364  N NZ  . LYS B 1 286 ? 92.296  72.643  147.836 1.00 82.13 ? 286 LYS B NZ  1 
ATOM   5365  N N   . THR B 1 287 ? 91.098  77.946  148.870 1.00 84.35 ? 287 THR B N   1 
ATOM   5366  C CA  . THR B 1 287 ? 89.651  77.888  148.769 1.00 84.35 ? 287 THR B CA  1 
ATOM   5367  C C   . THR B 1 287 ? 89.122  79.277  148.440 1.00 84.35 ? 287 THR B C   1 
ATOM   5368  O O   . THR B 1 287 ? 89.777  80.283  148.719 1.00 84.35 ? 287 THR B O   1 
ATOM   5369  C CB  . THR B 1 287 ? 89.045  77.384  150.087 1.00 84.35 ? 287 THR B CB  1 
ATOM   5370  O OG1 . THR B 1 287 ? 89.651  76.137  150.444 1.00 84.35 ? 287 THR B OG1 1 
ATOM   5371  C CG2 . THR B 1 287 ? 87.553  77.164  149.958 1.00 84.35 ? 287 THR B CG2 1 
ATOM   5372  N N   . LEU B 1 288 ? 87.938  79.335  147.829 1.00 84.09 ? 288 LEU B N   1 
ATOM   5373  C CA  . LEU B 1 288 ? 87.288  80.629  147.667 1.00 84.09 ? 288 LEU B CA  1 
ATOM   5374  C C   . LEU B 1 288 ? 86.838  81.168  149.016 1.00 84.09 ? 288 LEU B C   1 
ATOM   5375  O O   . LEU B 1 288 ? 86.942  82.373  149.279 1.00 84.09 ? 288 LEU B O   1 
ATOM   5376  C CB  . LEU B 1 288 ? 86.114  80.522  146.692 1.00 84.09 ? 288 LEU B CB  1 
ATOM   5377  C CG  . LEU B 1 288 ? 84.856  79.751  147.080 1.00 84.09 ? 288 LEU B CG  1 
ATOM   5378  C CD1 . LEU B 1 288 ? 83.818  80.696  147.642 1.00 84.09 ? 288 LEU B CD1 1 
ATOM   5379  C CD2 . LEU B 1 288 ? 84.305  79.014  145.884 1.00 84.09 ? 288 LEU B CD2 1 
ATOM   5380  N N   . GLU B 1 289 ? 86.352  80.288  149.890 1.00 86.16 ? 289 GLU B N   1 
ATOM   5381  C CA  . GLU B 1 289 ? 86.074  80.689  151.262 1.00 86.16 ? 289 GLU B CA  1 
ATOM   5382  C C   . GLU B 1 289 ? 87.302  81.330  151.893 1.00 86.16 ? 289 GLU B C   1 
ATOM   5383  O O   . GLU B 1 289 ? 87.218  82.405  152.498 1.00 86.16 ? 289 GLU B O   1 
ATOM   5384  C CB  . GLU B 1 289 ? 85.620  79.477  152.072 1.00 86.16 ? 289 GLU B CB  1 
ATOM   5385  C CG  . GLU B 1 289 ? 85.484  79.735  153.558 1.00 86.16 ? 289 GLU B CG  1 
ATOM   5386  C CD  . GLU B 1 289 ? 86.787  79.537  154.304 1.00 86.16 ? 289 GLU B CD  1 
ATOM   5387  O OE1 . GLU B 1 289 ? 87.684  78.861  153.762 1.00 86.16 ? 289 GLU B OE1 1 
ATOM   5388  O OE2 . GLU B 1 289 ? 86.915  80.066  155.427 1.00 86.16 ? 289 GLU B OE2 1 
ATOM   5389  N N   . GLU B 1 290 ? 88.455  80.670  151.769 1.00 85.79 ? 290 GLU B N   1 
ATOM   5390  C CA  . GLU B 1 290 ? 89.701  81.236  152.268 1.00 85.79 ? 290 GLU B CA  1 
ATOM   5391  C C   . GLU B 1 290 ? 89.925  82.638  151.738 1.00 85.79 ? 290 GLU B C   1 
ATOM   5392  O O   . GLU B 1 290 ? 90.356  83.526  152.479 1.00 85.79 ? 290 GLU B O   1 
ATOM   5393  C CB  . GLU B 1 290 ? 90.875  80.349  151.876 1.00 85.79 ? 290 GLU B CB  1 
ATOM   5394  C CG  . GLU B 1 290 ? 92.215  80.927  152.258 1.00 85.79 ? 290 GLU B CG  1 
ATOM   5395  C CD  . GLU B 1 290 ? 93.363  80.044  151.831 1.00 85.79 ? 290 GLU B CD  1 
ATOM   5396  O OE1 . GLU B 1 290 ? 93.092  78.976  151.246 1.00 85.79 ? 290 GLU B OE1 1 
ATOM   5397  O OE2 . GLU B 1 290 ? 94.531  80.416  152.067 1.00 85.79 ? 290 GLU B OE2 1 
ATOM   5398  N N   . ALA B 1 291 ? 89.642  82.858  150.456 1.00 83.76 ? 291 ALA B N   1 
ATOM   5399  C CA  . ALA B 1 291 ? 89.876  84.165  149.862 1.00 83.76 ? 291 ALA B CA  1 
ATOM   5400  C C   . ALA B 1 291 ? 88.875  85.204  150.330 1.00 83.76 ? 291 ALA B C   1 
ATOM   5401  O O   . ALA B 1 291 ? 89.174  86.398  150.260 1.00 83.76 ? 291 ALA B O   1 
ATOM   5402  C CB  . ALA B 1 291 ? 89.843  84.077  148.336 1.00 83.76 ? 291 ALA B CB  1 
ATOM   5403  N N   . TYR B 1 292 ? 87.706  84.782  150.812 1.00 82.24 ? 292 TYR B N   1 
ATOM   5404  C CA  . TYR B 1 292 ? 86.717  85.746  151.282 1.00 82.24 ? 292 TYR B CA  1 
ATOM   5405  C C   . TYR B 1 292 ? 87.283  86.703  152.315 1.00 82.24 ? 292 TYR B C   1 
ATOM   5406  O O   . TYR B 1 292 ? 86.760  87.812  152.473 1.00 82.24 ? 292 TYR B O   1 
ATOM   5407  C CB  . TYR B 1 292 ? 85.513  85.025  151.872 1.00 82.24 ? 292 TYR B CB  1 
ATOM   5408  C CG  . TYR B 1 292 ? 84.382  85.955  152.209 1.00 82.24 ? 292 TYR B CG  1 
ATOM   5409  C CD1 . TYR B 1 292 ? 84.078  87.031  151.390 1.00 82.24 ? 292 TYR B CD1 1 
ATOM   5410  C CD2 . TYR B 1 292 ? 83.617  85.762  153.348 1.00 82.24 ? 292 TYR B CD2 1 
ATOM   5411  C CE1 . TYR B 1 292 ? 83.045  87.886  151.694 1.00 82.24 ? 292 TYR B CE1 1 
ATOM   5412  C CE2 . TYR B 1 292 ? 82.579  86.613  153.660 1.00 82.24 ? 292 TYR B CE2 1 
ATOM   5413  C CZ  . TYR B 1 292 ? 82.298  87.670  152.828 1.00 82.24 ? 292 TYR B CZ  1 
ATOM   5414  O OH  . TYR B 1 292 ? 81.265  88.519  153.134 1.00 82.24 ? 292 TYR B OH  1 
ATOM   5415  N N   . SER B 1 293 ? 88.345  86.308  153.015 1.00 79.70 ? 293 SER B N   1 
ATOM   5416  C CA  . SER B 1 293 ? 88.970  87.210  153.971 1.00 79.70 ? 293 SER B CA  1 
ATOM   5417  C C   . SER B 1 293 ? 89.432  88.491  153.287 1.00 79.70 ? 293 SER B C   1 
ATOM   5418  O O   . SER B 1 293 ? 89.085  89.597  153.716 1.00 79.70 ? 293 SER B O   1 
ATOM   5419  C CB  . SER B 1 293 ? 90.137  86.509  154.664 1.00 79.70 ? 293 SER B CB  1 
ATOM   5420  O OG  . SER B 1 293 ? 91.294  86.528  153.854 1.00 79.70 ? 293 SER B OG  1 
ATOM   5421  N N   . PHE B 1 294 ? 90.205  88.360  152.208 1.00 77.92 ? 294 PHE B N   1 
ATOM   5422  C CA  . PHE B 1 294 ? 90.735  89.536  151.522 1.00 77.92 ? 294 PHE B CA  1 
ATOM   5423  C C   . PHE B 1 294 ? 89.627  90.419  150.977 1.00 77.92 ? 294 PHE B C   1 
ATOM   5424  O O   . PHE B 1 294 ? 89.716  91.646  151.038 1.00 77.92 ? 294 PHE B O   1 
ATOM   5425  C CB  . PHE B 1 294 ? 91.658  89.112  150.392 1.00 77.92 ? 294 PHE B CB  1 
ATOM   5426  C CG  . PHE B 1 294 ? 92.931  88.528  150.859 1.00 77.92 ? 294 PHE B CG  1 
ATOM   5427  C CD1 . PHE B 1 294 ? 92.974  87.240  151.344 1.00 77.92 ? 294 PHE B CD1 1 
ATOM   5428  C CD2 . PHE B 1 294 ? 94.086  89.270  150.824 1.00 77.92 ? 294 PHE B CD2 1 
ATOM   5429  C CE1 . PHE B 1 294 ? 94.150  86.703  151.778 1.00 77.92 ? 294 PHE B CE1 1 
ATOM   5430  C CE2 . PHE B 1 294 ? 95.263  88.740  151.255 1.00 77.92 ? 294 PHE B CE2 1 
ATOM   5431  C CZ  . PHE B 1 294 ? 95.295  87.454  151.735 1.00 77.92 ? 294 PHE B CZ  1 
ATOM   5432  N N   . TRP B 1 295 ? 88.584  89.815  150.424 1.00 76.90 ? 295 TRP B N   1 
ATOM   5433  C CA  . TRP B 1 295 ? 87.445  90.600  149.981 1.00 76.90 ? 295 TRP B CA  1 
ATOM   5434  C C   . TRP B 1 295 ? 86.774  91.314  151.144 1.00 76.90 ? 295 TRP B C   1 
ATOM   5435  O O   . TRP B 1 295 ? 86.187  92.385  150.954 1.00 76.90 ? 295 TRP B O   1 
ATOM   5436  C CB  . TRP B 1 295 ? 86.439  89.702  149.272 1.00 76.90 ? 295 TRP B CB  1 
ATOM   5437  C CG  . TRP B 1 295 ? 85.329  90.461  148.680 1.00 76.90 ? 295 TRP B CG  1 
ATOM   5438  C CD1 . TRP B 1 295 ? 84.092  90.647  149.204 1.00 76.90 ? 295 TRP B CD1 1 
ATOM   5439  C CD2 . TRP B 1 295 ? 85.356  91.166  147.449 1.00 76.90 ? 295 TRP B CD2 1 
ATOM   5440  N NE1 . TRP B 1 295 ? 83.340  91.423  148.371 1.00 76.90 ? 295 TRP B NE1 1 
ATOM   5441  C CE2 . TRP B 1 295 ? 84.097  91.754  147.280 1.00 76.90 ? 295 TRP B CE2 1 
ATOM   5442  C CE3 . TRP B 1 295 ? 86.326  91.353  146.463 1.00 76.90 ? 295 TRP B CE3 1 
ATOM   5443  C CZ2 . TRP B 1 295 ? 83.781  92.519  146.169 1.00 76.90 ? 295 TRP B CZ2 1 
ATOM   5444  C CZ3 . TRP B 1 295 ? 86.014  92.107  145.367 1.00 76.90 ? 295 TRP B CZ3 1 
ATOM   5445  C CH2 . TRP B 1 295 ? 84.754  92.683  145.225 1.00 76.90 ? 295 TRP B CH2 1 
ATOM   5446  N N   . SER B 1 296 ? 86.851  90.744  152.349 1.00 79.59 ? 296 SER B N   1 
ATOM   5447  C CA  . SER B 1 296 ? 86.133  91.245  153.514 1.00 79.59 ? 296 SER B CA  1 
ATOM   5448  C C   . SER B 1 296 ? 87.027  91.872  154.572 1.00 79.59 ? 296 SER B C   1 
ATOM   5449  O O   . SER B 1 296 ? 86.510  92.335  155.594 1.00 79.59 ? 296 SER B O   1 
ATOM   5450  C CB  . SER B 1 296 ? 85.336  90.110  154.156 1.00 79.59 ? 296 SER B CB  1 
ATOM   5451  O OG  . SER B 1 296 ? 86.185  89.012  154.420 1.00 79.59 ? 296 SER B OG  1 
ATOM   5452  N N   . LEU B 1 297 ? 88.343  91.891  154.373 1.00 77.57 ? 297 LEU B N   1 
ATOM   5453  C CA  . LEU B 1 297 ? 89.273  92.377  155.392 1.00 77.57 ? 297 LEU B CA  1 
ATOM   5454  C C   . LEU B 1 297 ? 89.102  91.612  156.698 1.00 77.57 ? 297 LEU B C   1 
ATOM   5455  O O   . LEU B 1 297 ? 89.236  92.165  157.789 1.00 77.57 ? 297 LEU B O   1 
ATOM   5456  C CB  . LEU B 1 297 ? 89.109  93.875  155.632 1.00 77.57 ? 297 LEU B CB  1 
ATOM   5457  C CG  . LEU B 1 297 ? 89.682  94.841  154.612 1.00 77.57 ? 297 LEU B CG  1 
ATOM   5458  C CD1 . LEU B 1 297 ? 89.470  96.233  155.116 1.00 77.57 ? 297 LEU B CD1 1 
ATOM   5459  C CD2 . LEU B 1 297 ? 91.149  94.574  154.448 1.00 77.57 ? 297 LEU B CD2 1 
ATOM   5460  N N   . GLY B 1 298 ? 88.806  90.324  156.587 1.00 79.52 ? 298 GLY B N   1 
ATOM   5461  C CA  . GLY B 1 298 ? 88.604  89.495  157.753 1.00 79.52 ? 298 GLY B CA  1 
ATOM   5462  C C   . GLY B 1 298 ? 87.245  89.615  158.392 1.00 79.52 ? 298 GLY B C   1 
ATOM   5463  O O   . GLY B 1 298 ? 87.115  89.329  159.586 1.00 79.52 ? 298 GLY B O   1 
ATOM   5464  N N   . GLY B 1 299 ? 86.230  90.027  157.646 1.00 81.06 ? 299 GLY B N   1 
ATOM   5465  C CA  . GLY B 1 299 ? 84.907  90.215  158.191 1.00 81.06 ? 299 GLY B CA  1 
ATOM   5466  C C   . GLY B 1 299 ? 84.625  91.618  158.677 1.00 81.06 ? 299 GLY B C   1 
ATOM   5467  O O   . GLY B 1 299 ? 83.452  91.987  158.806 1.00 81.06 ? 299 GLY B O   1 
ATOM   5468  N N   . ARG B 1 300 ? 85.663  92.409  158.942 1.00 80.69 ? 300 ARG B N   1 
ATOM   5469  C CA  . ARG B 1 300 ? 85.448  93.787  159.363 1.00 80.69 ? 300 ARG B CA  1 
ATOM   5470  C C   . ARG B 1 300 ? 84.718  94.575  158.288 1.00 80.69 ? 300 ARG B C   1 
ATOM   5471  O O   . ARG B 1 300 ? 83.714  95.242  158.563 1.00 80.69 ? 300 ARG B O   1 
ATOM   5472  C CB  . ARG B 1 300 ? 86.784  94.442  159.698 1.00 80.69 ? 300 ARG B CB  1 
ATOM   5473  C CG  . ARG B 1 300 ? 87.532  93.734  160.793 1.00 80.69 ? 300 ARG B CG  1 
ATOM   5474  C CD  . ARG B 1 300 ? 89.015  93.816  160.589 1.00 80.69 ? 300 ARG B CD  1 
ATOM   5475  N NE  . ARG B 1 300 ? 89.734  93.241  161.717 1.00 80.69 ? 300 ARG B NE  1 
ATOM   5476  C CZ  . ARG B 1 300 ? 90.052  91.957  161.820 1.00 80.69 ? 300 ARG B CZ  1 
ATOM   5477  N NH1 . ARG B 1 300 ? 89.717  91.111  160.859 1.00 80.69 ? 300 ARG B NH1 1 
ATOM   5478  N NH2 . ARG B 1 300 ? 90.713  91.519  162.881 1.00 80.69 ? 300 ARG B NH2 1 
ATOM   5479  N N   . LEU B 1 301 ? 85.199  94.494  157.052 1.00 82.46 ? 301 LEU B N   1 
ATOM   5480  C CA  . LEU B 1 301 ? 84.632  95.250  155.941 1.00 82.46 ? 301 LEU B CA  1 
ATOM   5481  C C   . LEU B 1 301 ? 83.476  94.435  155.385 1.00 82.46 ? 301 LEU B C   1 
ATOM   5482  O O   . LEU B 1 301 ? 83.665  93.522  154.584 1.00 82.46 ? 301 LEU B O   1 
ATOM   5483  C CB  . LEU B 1 301 ? 85.685  95.519  154.879 1.00 82.46 ? 301 LEU B CB  1 
ATOM   5484  C CG  . LEU B 1 301 ? 85.383  96.643  153.892 1.00 82.46 ? 301 LEU B CG  1 
ATOM   5485  C CD1 . LEU B 1 301 ? 86.664  97.130  153.282 1.00 82.46 ? 301 LEU B CD1 1 
ATOM   5486  C CD2 . LEU B 1 301 ? 84.435  96.211  152.813 1.00 82.46 ? 301 LEU B CD2 1 
ATOM   5487  N N   . SER B 1 302 ? 82.267  94.776  155.803 1.00 86.03 ? 302 SER B N   1 
ATOM   5488  C CA  . SER B 1 302 ? 81.086  94.023  155.420 1.00 86.03 ? 302 SER B CA  1 
ATOM   5489  C C   . SER B 1 302 ? 79.957  94.977  155.069 1.00 86.03 ? 302 SER B C   1 
ATOM   5490  O O   . SER B 1 302 ? 79.769  96.000  155.732 1.00 86.03 ? 302 SER B O   1 
ATOM   5491  C CB  . SER B 1 302 ? 80.652  93.094  156.547 1.00 86.03 ? 302 SER B CB  1 
ATOM   5492  O OG  . SER B 1 302 ? 81.671  92.157  156.840 1.00 86.03 ? 302 SER B OG  1 
ATOM   5493  N N   . GLY B 1 303 ? 79.196  94.630  154.032 1.00 94.42 ? 303 GLY B N   1 
ATOM   5494  C CA  . GLY B 1 303 ? 78.098  95.455  153.594 1.00 94.42 ? 303 GLY B CA  1 
ATOM   5495  C C   . GLY B 1 303 ? 77.097  94.719  152.726 1.00 94.42 ? 303 GLY B C   1 
ATOM   5496  O O   . GLY B 1 303 ? 77.248  93.532  152.427 1.00 94.42 ? 303 GLY B O   1 
ATOM   5497  N N   . PRO B 1 304 ? 76.031  95.416  152.324 1.00 97.23 ? 304 PRO B N   1 
ATOM   5498  C CA  . PRO B 1 304 ? 75.076  94.803  151.386 1.00 97.23 ? 304 PRO B CA  1 
ATOM   5499  C C   . PRO B 1 304 ? 75.654  94.563  150.003 1.00 97.23 ? 304 PRO B C   1 
ATOM   5500  O O   . PRO B 1 304 ? 75.010  93.900  149.181 1.00 97.23 ? 304 PRO B O   1 
ATOM   5501  C CB  . PRO B 1 304 ? 73.925  95.819  151.349 1.00 97.23 ? 304 PRO B CB  1 
ATOM   5502  C CG  . PRO B 1 304 ? 74.058  96.598  152.603 1.00 97.23 ? 304 PRO B CG  1 
ATOM   5503  C CD  . PRO B 1 304 ? 75.523  96.678  152.882 1.00 97.23 ? 304 PRO B CD  1 
ATOM   5504  N N   . GLU B 1 305 ? 76.837  95.104  149.706 1.00 96.29 ? 305 GLU B N   1 
ATOM   5505  C CA  . GLU B 1 305 ? 77.426  94.887  148.389 1.00 96.29 ? 305 GLU B CA  1 
ATOM   5506  C C   . GLU B 1 305 ? 78.664  94.004  148.473 1.00 96.29 ? 305 GLU B C   1 
ATOM   5507  O O   . GLU B 1 305 ? 79.113  93.450  147.459 1.00 96.29 ? 305 GLU B O   1 
ATOM   5508  C CB  . GLU B 1 305 ? 77.766  96.226  147.738 1.00 96.29 ? 305 GLU B CB  1 
ATOM   5509  C CG  . GLU B 1 305 ? 76.551  97.046  147.346 1.00 96.29 ? 305 GLU B CG  1 
ATOM   5510  C CD  . GLU B 1 305 ? 76.073  97.950  148.462 1.00 96.29 ? 305 GLU B CD  1 
ATOM   5511  O OE1 . GLU B 1 305 ? 75.817  99.141  148.191 1.00 96.29 ? 305 GLU B OE1 1 
ATOM   5512  O OE2 . GLU B 1 305 ? 75.971  97.478  149.611 1.00 96.29 ? 305 GLU B OE2 1 
ATOM   5513  N N   . ILE B 1 306 ? 79.229  93.866  149.673 1.00 92.62 ? 306 ILE B N   1 
ATOM   5514  C CA  . ILE B 1 306 ? 80.401  93.017  149.857 1.00 92.62 ? 306 ILE B CA  1 
ATOM   5515  C C   . ILE B 1 306 ? 80.067  91.570  149.527 1.00 92.62 ? 306 ILE B C   1 
ATOM   5516  O O   . ILE B 1 306 ? 80.939  90.789  149.128 1.00 92.62 ? 306 ILE B O   1 
ATOM   5517  C CB  . ILE B 1 306 ? 80.937  93.164  151.290 1.00 92.62 ? 306 ILE B CB  1 
ATOM   5518  C CG1 . ILE B 1 306 ? 81.281  94.620  151.548 1.00 92.62 ? 306 ILE B CG1 1 
ATOM   5519  C CG2 . ILE B 1 306 ? 82.164  92.315  151.490 1.00 92.62 ? 306 ILE B CG2 1 
ATOM   5520  C CD1 . ILE B 1 306 ? 82.143  95.198  150.468 1.00 92.62 ? 306 ILE B CD1 1 
ATOM   5521  N N   . ASP B 1 307 ? 78.799  91.189  149.684 1.00 96.64 ? 307 ASP B N   1 
ATOM   5522  C CA  . ASP B 1 307 ? 78.381  89.843  149.315 1.00 96.64 ? 307 ASP B CA  1 
ATOM   5523  C C   . ASP B 1 307 ? 77.986  89.770  147.845 1.00 96.64 ? 307 ASP B C   1 
ATOM   5524  O O   . ASP B 1 307 ? 78.256  88.765  147.173 1.00 96.64 ? 307 ASP B O   1 
ATOM   5525  C CB  . ASP B 1 307 ? 77.232  89.402  150.216 1.00 96.64 ? 307 ASP B CB  1 
ATOM   5526  C CG  . ASP B 1 307 ? 76.061  90.356  150.163 1.00 96.64 ? 307 ASP B CG  1 
ATOM   5527  O OD1 . ASP B 1 307 ? 76.154  91.370  149.442 1.00 96.64 ? 307 ASP B OD1 1 
ATOM   5528  O OD2 . ASP B 1 307 ? 75.053  90.103  150.852 1.00 96.64 ? 307 ASP B OD2 1 
ATOM   5529  N N   . TYR B 1 308 ? 77.334  90.822  147.333 1.00 93.95 ? 308 TYR B N   1 
ATOM   5530  C CA  . TYR B 1 308 ? 77.023  90.881  145.908 1.00 93.95 ? 308 TYR B CA  1 
ATOM   5531  C C   . TYR B 1 308 ? 78.263  90.626  145.072 1.00 93.95 ? 308 TYR B C   1 
ATOM   5532  O O   . TYR B 1 308 ? 78.250  89.784  144.168 1.00 93.95 ? 308 TYR B O   1 
ATOM   5533  C CB  . TYR B 1 308 ? 76.437  92.241  145.537 1.00 93.95 ? 308 TYR B CB  1 
ATOM   5534  C CG  . TYR B 1 308 ? 75.075  92.525  146.100 1.00 93.95 ? 308 TYR B CG  1 
ATOM   5535  C CD1 . TYR B 1 308 ? 74.398  91.576  146.843 1.00 93.95 ? 308 TYR B CD1 1 
ATOM   5536  C CD2 . TYR B 1 308 ? 74.462  93.748  145.885 1.00 93.95 ? 308 TYR B CD2 1 
ATOM   5537  C CE1 . TYR B 1 308 ? 73.155  91.840  147.363 1.00 93.95 ? 308 TYR B CE1 1 
ATOM   5538  C CE2 . TYR B 1 308 ? 73.219  94.021  146.398 1.00 93.95 ? 308 TYR B CE2 1 
ATOM   5539  C CZ  . TYR B 1 308 ? 72.569  93.063  147.137 1.00 93.95 ? 308 TYR B CZ  1 
ATOM   5540  O OH  . TYR B 1 308 ? 71.324  93.326  147.655 1.00 93.95 ? 308 TYR B OH  1 
ATOM   5541  N N   . GLY B 1 309 ? 79.350  91.339  145.367 1.00 88.86 ? 309 GLY B N   1 
ATOM   5542  C CA  . GLY B 1 309 ? 80.571  91.151  144.605 1.00 88.86 ? 309 GLY B CA  1 
ATOM   5543  C C   . GLY B 1 309 ? 81.210  89.796  144.800 1.00 88.86 ? 309 GLY B C   1 
ATOM   5544  O O   . GLY B 1 309 ? 81.694  89.196  143.828 1.00 88.86 ? 309 GLY B O   1 
ATOM   5545  N N   . PHE B 1 310 ? 81.205  89.287  146.032 1.00 87.24 ? 310 PHE B N   1 
ATOM   5546  C CA  . PHE B 1 310 ? 81.889  88.030  146.300 1.00 87.24 ? 310 PHE B CA  1 
ATOM   5547  C C   . PHE B 1 310 ? 81.183  86.860  145.632 1.00 87.24 ? 310 PHE B C   1 
ATOM   5548  O O   . PHE B 1 310 ? 81.837  85.907  145.194 1.00 87.24 ? 310 PHE B O   1 
ATOM   5549  C CB  . PHE B 1 310 ? 82.002  87.795  147.799 1.00 87.24 ? 310 PHE B CB  1 
ATOM   5550  C CG  . PHE B 1 310 ? 82.555  86.453  148.145 1.00 87.24 ? 310 PHE B CG  1 
ATOM   5551  C CD1 . PHE B 1 310 ? 83.893  86.168  147.935 1.00 87.24 ? 310 PHE B CD1 1 
ATOM   5552  C CD2 . PHE B 1 310 ? 81.738  85.469  148.665 1.00 87.24 ? 310 PHE B CD2 1 
ATOM   5553  C CE1 . PHE B 1 310 ? 84.406  84.930  148.249 1.00 87.24 ? 310 PHE B CE1 1 
ATOM   5554  C CE2 . PHE B 1 310 ? 82.246  84.226  148.978 1.00 87.24 ? 310 PHE B CE2 1 
ATOM   5555  C CZ  . PHE B 1 310 ? 83.581  83.957  148.771 1.00 87.24 ? 310 PHE B CZ  1 
ATOM   5556  N N   . LYS B 1 311 ? 79.854  86.900  145.551 1.00 87.97 ? 311 LYS B N   1 
ATOM   5557  C CA  . LYS B 1 311 ? 79.146  85.823  144.870 1.00 87.97 ? 311 LYS B CA  1 
ATOM   5558  C C   . LYS B 1 311 ? 79.607  85.706  143.428 1.00 87.97 ? 311 LYS B C   1 
ATOM   5559  O O   . LYS B 1 311 ? 79.919  84.610  142.945 1.00 87.97 ? 311 LYS B O   1 
ATOM   5560  C CB  . LYS B 1 311 ? 77.642  86.062  144.921 1.00 87.97 ? 311 LYS B CB  1 
ATOM   5561  C CG  . LYS B 1 311 ? 76.826  84.996  144.205 1.00 87.97 ? 311 LYS B CG  1 
ATOM   5562  C CD  . LYS B 1 311 ? 76.538  85.370  142.756 1.00 87.97 ? 311 LYS B CD  1 
ATOM   5563  C CE  . LYS B 1 311 ? 75.807  86.693  142.658 1.00 87.97 ? 311 LYS B CE  1 
ATOM   5564  N NZ  . LYS B 1 311 ? 75.430  86.993  141.251 1.00 87.97 ? 311 LYS B NZ  1 
ATOM   5565  N N   . ILE B 1 312 ? 79.635  86.834  142.718 1.00 85.82 ? 312 ILE B N   1 
ATOM   5566  C CA  . ILE B 1 312 ? 80.034  86.829  141.316 1.00 85.82 ? 312 ILE B CA  1 
ATOM   5567  C C   . ILE B 1 312 ? 81.473  86.368  141.177 1.00 85.82 ? 312 ILE B C   1 
ATOM   5568  O O   . ILE B 1 312 ? 81.815  85.611  140.255 1.00 85.82 ? 312 ILE B O   1 
ATOM   5569  C CB  . ILE B 1 312 ? 79.824  88.222  140.698 1.00 85.82 ? 312 ILE B CB  1 
ATOM   5570  C CG1 . ILE B 1 312 ? 78.502  88.816  141.174 1.00 85.82 ? 312 ILE B CG1 1 
ATOM   5571  C CG2 . ILE B 1 312 ? 79.825  88.135  139.195 1.00 85.82 ? 312 ILE B CG2 1 
ATOM   5572  C CD1 . ILE B 1 312 ? 78.170  90.156  140.559 1.00 85.82 ? 312 ILE B CD1 1 
ATOM   5573  N N   . VAL B 1 313 ? 82.342  86.802  142.091 1.00 84.03 ? 313 VAL B N   1 
ATOM   5574  C CA  . VAL B 1 313 ? 83.731  86.402  141.918 1.00 84.03 ? 313 VAL B CA  1 
ATOM   5575  C C   . VAL B 1 313 ? 83.903  84.919  142.187 1.00 84.03 ? 313 VAL B C   1 
ATOM   5576  O O   . VAL B 1 313 ? 84.695  84.258  141.515 1.00 84.03 ? 313 VAL B O   1 
ATOM   5577  C CB  . VAL B 1 313 ? 84.687  87.246  142.775 1.00 84.03 ? 313 VAL B CB  1 
ATOM   5578  C CG1 . VAL B 1 313 ? 84.698  86.788  144.211 1.00 84.03 ? 313 VAL B CG1 1 
ATOM   5579  C CG2 . VAL B 1 313 ? 86.072  87.178  142.175 1.00 84.03 ? 313 VAL B CG2 1 
ATOM   5580  N N   . SER B 1 314 ? 83.163  84.342  143.134 1.00 85.53 ? 314 SER B N   1 
ATOM   5581  C CA  . SER B 1 314 ? 83.275  82.905  143.347 1.00 85.53 ? 314 SER B CA  1 
ATOM   5582  C C   . SER B 1 314 ? 82.713  82.137  142.162 1.00 85.53 ? 314 SER B C   1 
ATOM   5583  O O   . SER B 1 314 ? 83.256  81.091  141.766 1.00 85.53 ? 314 SER B O   1 
ATOM   5584  C CB  . SER B 1 314 ? 82.553  82.511  144.631 1.00 85.53 ? 314 SER B CB  1 
ATOM   5585  O OG  . SER B 1 314 ? 81.188  82.876  144.567 1.00 85.53 ? 314 SER B OG  1 
ATOM   5586  N N   . GLN B 1 315 ? 81.623  82.643  141.590 1.00 84.24 ? 315 GLN B N   1 
ATOM   5587  C CA  . GLN B 1 315 ? 81.039  82.046  140.399 1.00 84.24 ? 315 GLN B CA  1 
ATOM   5588  C C   . GLN B 1 315 ? 82.068  81.954  139.282 1.00 84.24 ? 315 GLN B C   1 
ATOM   5589  O O   . GLN B 1 315 ? 82.364  80.864  138.774 1.00 84.24 ? 315 GLN B O   1 
ATOM   5590  C CB  . GLN B 1 315 ? 79.826  82.874  139.978 1.00 84.24 ? 315 GLN B CB  1 
ATOM   5591  C CG  . GLN B 1 315 ? 79.368  82.714  138.552 1.00 84.24 ? 315 GLN B CG  1 
ATOM   5592  C CD  . GLN B 1 315 ? 78.297  83.728  138.205 1.00 84.24 ? 315 GLN B CD  1 
ATOM   5593  O OE1 . GLN B 1 315 ? 77.902  84.535  139.044 1.00 84.24 ? 315 GLN B OE1 1 
ATOM   5594  N NE2 . GLN B 1 315 ? 77.819  83.691  136.969 1.00 84.24 ? 315 GLN B NE2 1 
ATOM   5595  N N   . MET B 1 316 ? 82.650  83.091  138.904 1.00 82.57 ? 316 MET B N   1 
ATOM   5596  C CA  . MET B 1 316 ? 83.639  83.053  137.833 1.00 82.57 ? 316 MET B CA  1 
ATOM   5597  C C   . MET B 1 316 ? 84.885  82.294  138.265 1.00 82.57 ? 316 MET B C   1 
ATOM   5598  O O   . MET B 1 316 ? 85.576  81.708  137.427 1.00 82.57 ? 316 MET B O   1 
ATOM   5599  C CB  . MET B 1 316 ? 83.993  84.470  137.389 1.00 82.57 ? 316 MET B CB  1 
ATOM   5600  C CG  . MET B 1 316 ? 84.771  84.548  136.083 1.00 82.57 ? 316 MET B CG  1 
ATOM   5601  S SD  . MET B 1 316 ? 86.545  84.308  136.235 1.00 82.57 ? 316 MET B SD  1 
ATOM   5602  C CE  . MET B 1 316 ? 87.032  85.841  137.005 1.00 82.57 ? 316 MET B CE  1 
ATOM   5603  N N   . TRP B 1 317 ? 85.163  82.263  139.566 1.00 84.09 ? 317 TRP B N   1 
ATOM   5604  C CA  . TRP B 1 317 ? 86.302  81.526  140.094 1.00 84.09 ? 317 TRP B CA  1 
ATOM   5605  C C   . TRP B 1 317 ? 86.216  80.057  139.725 1.00 84.09 ? 317 TRP B C   1 
ATOM   5606  O O   . TRP B 1 317 ? 87.076  79.529  139.012 1.00 84.09 ? 317 TRP B O   1 
ATOM   5607  C CB  . TRP B 1 317 ? 86.340  81.708  141.610 1.00 84.09 ? 317 TRP B CB  1 
ATOM   5608  C CG  . TRP B 1 317 ? 87.204  80.774  142.393 1.00 84.09 ? 317 TRP B CG  1 
ATOM   5609  C CD1 . TRP B 1 317 ? 86.950  79.468  142.694 1.00 84.09 ? 317 TRP B CD1 1 
ATOM   5610  C CD2 . TRP B 1 317 ? 88.421  81.105  143.054 1.00 84.09 ? 317 TRP B CD2 1 
ATOM   5611  N NE1 . TRP B 1 317 ? 87.958  78.957  143.467 1.00 84.09 ? 317 TRP B NE1 1 
ATOM   5612  C CE2 . TRP B 1 317 ? 88.872  79.946  143.705 1.00 84.09 ? 317 TRP B CE2 1 
ATOM   5613  C CE3 . TRP B 1 317 ? 89.184  82.267  143.142 1.00 84.09 ? 317 TRP B CE3 1 
ATOM   5614  C CZ2 . TRP B 1 317 ? 90.046  79.919  144.438 1.00 84.09 ? 317 TRP B CZ2 1 
ATOM   5615  C CZ3 . TRP B 1 317 ? 90.350  82.235  143.866 1.00 84.09 ? 317 TRP B CZ3 1 
ATOM   5616  C CH2 . TRP B 1 317 ? 90.771  81.071  144.507 1.00 84.09 ? 317 TRP B CH2 1 
ATOM   5617  N N   . ASP B 1 318 ? 85.182  79.377  140.212 1.00 86.44 ? 318 ASP B N   1 
ATOM   5618  C CA  . ASP B 1 318 ? 85.087  77.963  139.880 1.00 86.44 ? 318 ASP B CA  1 
ATOM   5619  C C   . ASP B 1 318 ? 84.756  77.751  138.410 1.00 86.44 ? 318 ASP B C   1 
ATOM   5620  O O   . ASP B 1 318 ? 85.038  76.673  137.877 1.00 86.44 ? 318 ASP B O   1 
ATOM   5621  C CB  . ASP B 1 318 ? 84.094  77.243  140.798 1.00 86.44 ? 318 ASP B CB  1 
ATOM   5622  C CG  . ASP B 1 318 ? 82.650  77.614  140.537 1.00 86.44 ? 318 ASP B CG  1 
ATOM   5623  O OD1 . ASP B 1 318 ? 82.358  78.356  139.581 1.00 86.44 ? 318 ASP B OD1 1 
ATOM   5624  O OD2 . ASP B 1 318 ? 81.789  77.157  141.316 1.00 86.44 ? 318 ASP B OD2 1 
ATOM   5625  N N   . ALA B 1 319 ? 84.205  78.761  137.733 1.00 84.19 ? 319 ALA B N   1 
ATOM   5626  C CA  . ALA B 1 319 ? 84.045  78.670  136.288 1.00 84.19 ? 319 ALA B CA  1 
ATOM   5627  C C   . ALA B 1 319 ? 85.392  78.479  135.598 1.00 84.19 ? 319 ALA B C   1 
ATOM   5628  O O   . ALA B 1 319 ? 85.611  77.485  134.898 1.00 84.19 ? 319 ALA B O   1 
ATOM   5629  C CB  . ALA B 1 319 ? 83.336  79.918  135.763 1.00 84.19 ? 319 ALA B CB  1 
ATOM   5630  N N   . ILE B 1 320 ? 86.316  79.422  135.792 1.00 80.99 ? 320 ILE B N   1 
ATOM   5631  C CA  . ILE B 1 320 ? 87.591  79.363  135.080 1.00 80.99 ? 320 ILE B CA  1 
ATOM   5632  C C   . ILE B 1 320 ? 88.576  78.396  135.708 1.00 80.99 ? 320 ILE B C   1 
ATOM   5633  O O   . ILE B 1 320 ? 89.570  78.040  135.069 1.00 80.99 ? 320 ILE B O   1 
ATOM   5634  C CB  . ILE B 1 320 ? 88.266  80.742  134.988 1.00 80.99 ? 320 ILE B CB  1 
ATOM   5635  C CG1 . ILE B 1 320 ? 89.364  80.721  133.924 1.00 80.99 ? 320 ILE B CG1 1 
ATOM   5636  C CG2 . ILE B 1 320 ? 88.875  81.113  136.318 1.00 80.99 ? 320 ILE B CG2 1 
ATOM   5637  C CD1 . ILE B 1 320 ? 89.859  82.072  133.508 1.00 80.99 ? 320 ILE B CD1 1 
ATOM   5638  N N   . TYR B 1 321 ? 88.335  77.943  136.936 1.00 83.19 ? 321 TYR B N   1 
ATOM   5639  C CA  . TYR B 1 321 ? 89.199  76.938  137.536 1.00 83.19 ? 321 TYR B CA  1 
ATOM   5640  C C   . TYR B 1 321 ? 88.640  75.532  137.390 1.00 83.19 ? 321 TYR B C   1 
ATOM   5641  O O   . TYR B 1 321 ? 89.305  74.571  137.791 1.00 83.19 ? 321 TYR B O   1 
ATOM   5642  C CB  . TYR B 1 321 ? 89.436  77.261  139.010 1.00 83.19 ? 321 TYR B CB  1 
ATOM   5643  C CG  . TYR B 1 321 ? 90.319  78.461  139.197 1.00 83.19 ? 321 TYR B CG  1 
ATOM   5644  C CD1 . TYR B 1 321 ? 91.452  78.626  138.427 1.00 83.19 ? 321 TYR B CD1 1 
ATOM   5645  C CD2 . TYR B 1 321 ? 90.019  79.430  140.138 1.00 83.19 ? 321 TYR B CD2 1 
ATOM   5646  C CE1 . TYR B 1 321 ? 92.264  79.716  138.590 1.00 83.19 ? 321 TYR B CE1 1 
ATOM   5647  C CE2 . TYR B 1 321 ? 90.827  80.526  140.308 1.00 83.19 ? 321 TYR B CE2 1 
ATOM   5648  C CZ  . TYR B 1 321 ? 91.950  80.663  139.530 1.00 83.19 ? 321 TYR B CZ  1 
ATOM   5649  O OH  . TYR B 1 321 ? 92.771  81.753  139.684 1.00 83.19 ? 321 TYR B OH  1 
ATOM   5650  N N   . SER B 1 322 ? 87.436  75.400  136.834 1.00 85.76 ? 322 SER B N   1 
ATOM   5651  C CA  . SER B 1 322 ? 86.922  74.097  136.443 1.00 85.76 ? 322 SER B CA  1 
ATOM   5652  C C   . SER B 1 322 ? 87.808  73.444  135.393 1.00 85.76 ? 322 SER B C   1 
ATOM   5653  O O   . SER B 1 322 ? 88.039  72.230  135.433 1.00 85.76 ? 322 SER B O   1 
ATOM   5654  C CB  . SER B 1 322 ? 85.498  74.254  135.917 1.00 85.76 ? 322 SER B CB  1 
ATOM   5655  O OG  . SER B 1 322 ? 85.462  75.205  134.863 1.00 85.76 ? 322 SER B OG  1 
ATOM   5656  N N   . LYS B 1 323 ? 88.316  74.230  134.448 1.00 85.86 ? 323 LYS B N   1 
ATOM   5657  C CA  . LYS B 1 323 ? 89.122  73.673  133.376 1.00 85.86 ? 323 LYS B CA  1 
ATOM   5658  C C   . LYS B 1 323 ? 90.497  73.258  133.883 1.00 85.86 ? 323 LYS B C   1 
ATOM   5659  O O   . LYS B 1 323 ? 90.915  73.592  134.993 1.00 85.86 ? 323 LYS B O   1 
ATOM   5660  C CB  . LYS B 1 323 ? 89.289  74.674  132.237 1.00 85.86 ? 323 LYS B CB  1 
ATOM   5661  C CG  . LYS B 1 323 ? 88.027  75.408  131.882 1.00 85.86 ? 323 LYS B CG  1 
ATOM   5662  C CD  . LYS B 1 323 ? 86.897  74.456  131.570 1.00 85.86 ? 323 LYS B CD  1 
ATOM   5663  C CE  . LYS B 1 323 ? 85.583  75.209  131.499 1.00 85.86 ? 323 LYS B CE  1 
ATOM   5664  N NZ  . LYS B 1 323 ? 85.462  76.169  132.628 1.00 85.86 ? 323 LYS B NZ  1 
ATOM   5665  N N   . GLU B 1 324 ? 91.195  72.515  133.039 1.00 89.73 ? 324 GLU B N   1 
ATOM   5666  C CA  . GLU B 1 324 ? 92.540  72.059  133.324 1.00 89.73 ? 324 GLU B CA  1 
ATOM   5667  C C   . GLU B 1 324 ? 93.563  73.032  132.757 1.00 89.73 ? 324 GLU B C   1 
ATOM   5668  O O   . GLU B 1 324 ? 93.256  73.891  131.929 1.00 89.73 ? 324 GLU B O   1 
ATOM   5669  C CB  . GLU B 1 324 ? 92.769  70.671  132.733 1.00 89.73 ? 324 GLU B CB  1 
ATOM   5670  C CG  . GLU B 1 324 ? 92.954  70.684  131.230 1.00 89.73 ? 324 GLU B CG  1 
ATOM   5671  C CD  . GLU B 1 324 ? 91.657  70.935  130.495 1.00 89.73 ? 324 GLU B CD  1 
ATOM   5672  O OE1 . GLU B 1 324 ? 90.589  70.737  131.108 1.00 89.73 ? 324 GLU B OE1 1 
ATOM   5673  O OE2 . GLU B 1 324 ? 91.701  71.336  129.314 1.00 89.73 ? 324 GLU B OE2 1 
ATOM   5674  N N   . LEU B 1 325 ? 94.775  72.886  133.208 1.00 87.56 ? 325 LEU B N   1 
ATOM   5675  C CA  . LEU B 1 325 ? 95.839  73.681  132.638 1.00 87.56 ? 325 LEU B CA  1 
ATOM   5676  C C   . LEU B 1 325 ? 96.281  73.068  131.314 1.00 87.56 ? 325 LEU B C   1 
ATOM   5677  O O   . LEU B 1 325 ? 96.155  71.859  131.111 1.00 87.56 ? 325 LEU B O   1 
ATOM   5678  C CB  . LEU B 1 325 ? 97.013  73.753  133.603 1.00 87.56 ? 325 LEU B CB  1 
ATOM   5679  C CG  . LEU B 1 325 ? 98.069  74.838  133.407 1.00 87.56 ? 325 LEU B CG  1 
ATOM   5680  C CD1 . LEU B 1 325 ? 98.548  75.351  134.748 1.00 87.56 ? 325 LEU B CD1 1 
ATOM   5681  C CD2 . LEU B 1 325 ? 99.232  74.306  132.597 1.00 87.56 ? 325 LEU B CD2 1 
ATOM   5682  N N   . PRO B 1 326 ? 96.761  73.883  130.380 1.00 87.86 ? 326 PRO B N   1 
ATOM   5683  C CA  . PRO B 1 326 ? 97.308  73.325  129.138 1.00 87.86 ? 326 PRO B CA  1 
ATOM   5684  C C   . PRO B 1 326 ? 98.460  72.372  129.391 1.00 87.86 ? 326 PRO B C   1 
ATOM   5685  O O   . PRO B 1 326 ? 99.529  72.784  129.849 1.00 87.86 ? 326 PRO B O   1 
ATOM   5686  C CB  . PRO B 1 326 ? 97.770  74.567  128.370 1.00 87.86 ? 326 PRO B CB  1 
ATOM   5687  C CG  . PRO B 1 326 ? 96.894  75.645  128.856 1.00 87.86 ? 326 PRO B CG  1 
ATOM   5688  C CD  . PRO B 1 326 ? 96.585  75.342  130.294 1.00 87.86 ? 326 PRO B CD  1 
ATOM   5689  N N   . GLY B 1 327 ? 98.255  71.098  129.080 1.00 92.65 ? 327 GLY B N   1 
ATOM   5690  C CA  . GLY B 1 327 ? 99.271  70.092  129.286 1.00 92.65 ? 327 GLY B CA  1 
ATOM   5691  C C   . GLY B 1 327 ? 99.140  69.287  130.557 1.00 92.65 ? 327 GLY B C   1 
ATOM   5692  O O   . GLY B 1 327 ? 100.123 68.670  130.979 1.00 92.65 ? 327 GLY B O   1 
ATOM   5693  N N   . GLY B 1 328 ? 97.972  69.290  131.191 1.00 96.41 ? 328 GLY B N   1 
ATOM   5694  C CA  . GLY B 1 328 ? 97.729  68.444  132.338 1.00 96.41 ? 328 GLY B CA  1 
ATOM   5695  C C   . GLY B 1 328 ? 98.461  68.816  133.606 1.00 96.41 ? 328 GLY B C   1 
ATOM   5696  O O   . GLY B 1 328 ? 98.327  68.097  134.603 1.00 96.41 ? 328 GLY B O   1 
ATOM   5697  N N   . LYS B 1 329 ? 99.234  69.899  133.614 1.00 95.79 ? 329 LYS B N   1 
ATOM   5698  C CA  . LYS B 1 329 ? 99.883  70.324  134.846 1.00 95.79 ? 329 LYS B CA  1 
ATOM   5699  C C   . LYS B 1 329 ? 98.831  70.689  135.883 1.00 95.79 ? 329 LYS B C   1 
ATOM   5700  O O   . LYS B 1 329 ? 97.812  71.306  135.567 1.00 95.79 ? 329 LYS B O   1 
ATOM   5701  C CB  . LYS B 1 329 ? 100.809 71.508  134.584 1.00 95.79 ? 329 LYS B CB  1 
ATOM   5702  C CG  . LYS B 1 329 ? 102.051 71.147  133.790 1.00 95.79 ? 329 LYS B CG  1 
ATOM   5703  C CD  . LYS B 1 329 ? 103.078 72.264  133.828 1.00 95.79 ? 329 LYS B CD  1 
ATOM   5704  C CE  . LYS B 1 329 ? 103.420 72.650  135.258 1.00 95.79 ? 329 LYS B CE  1 
ATOM   5705  N NZ  . LYS B 1 329 ? 103.897 71.482  136.048 1.00 95.79 ? 329 LYS B NZ  1 
ATOM   5706  N N   . GLN B 1 330 ? 99.074  70.292  137.125 1.00 95.01 ? 330 GLN B N   1 
ATOM   5707  C CA  . GLN B 1 330 ? 98.053  70.416  138.152 1.00 95.01 ? 330 GLN B CA  1 
ATOM   5708  C C   . GLN B 1 330 ? 98.094  71.786  138.814 1.00 95.01 ? 330 GLN B C   1 
ATOM   5709  O O   . GLN B 1 330 ? 99.158  72.388  138.986 1.00 95.01 ? 330 GLN B O   1 
ATOM   5710  C CB  . GLN B 1 330 ? 98.219  69.321  139.202 1.00 95.01 ? 330 GLN B CB  1 
ATOM   5711  C CG  . GLN B 1 330 ? 97.961  67.941  138.653 1.00 95.01 ? 330 GLN B CG  1 
ATOM   5712  C CD  . GLN B 1 330 ? 96.560  67.808  138.097 1.00 95.01 ? 330 GLN B CD  1 
ATOM   5713  O OE1 . GLN B 1 330 ? 96.369  67.707  136.886 1.00 95.01 ? 330 GLN B OE1 1 
ATOM   5714  N NE2 . GLN B 1 330 ? 95.569  67.817  138.980 1.00 95.01 ? 330 GLN B NE2 1 
ATOM   5715  N N   . ARG B 1 331 ? 96.913  72.278  139.185 1.00 92.79 ? 331 ARG B N   1 
ATOM   5716  C CA  . ARG B 1 331 ? 96.785  73.554  139.879 1.00 92.79 ? 331 ARG B CA  1 
ATOM   5717  C C   . ARG B 1 331 ? 96.784  73.288  141.383 1.00 92.79 ? 331 ARG B C   1 
ATOM   5718  O O   . ARG B 1 331 ? 95.937  72.550  141.896 1.00 92.79 ? 331 ARG B O   1 
ATOM   5719  C CB  . ARG B 1 331 ? 95.532  74.304  139.419 1.00 92.79 ? 331 ARG B CB  1 
ATOM   5720  C CG  . ARG B 1 331 ? 94.199  73.676  139.789 1.00 92.79 ? 331 ARG B CG  1 
ATOM   5721  C CD  . ARG B 1 331 ? 93.024  74.496  139.276 1.00 92.79 ? 331 ARG B CD  1 
ATOM   5722  N NE  . ARG B 1 331 ? 92.901  74.444  137.823 1.00 92.79 ? 331 ARG B NE  1 
ATOM   5723  C CZ  . ARG B 1 331 ? 93.200  75.450  137.012 1.00 92.79 ? 331 ARG B CZ  1 
ATOM   5724  N NH1 . ARG B 1 331 ? 93.650  76.590  137.509 1.00 92.79 ? 331 ARG B NH1 1 
ATOM   5725  N NH2 . ARG B 1 331 ? 93.059  75.313  135.704 1.00 92.79 ? 331 ARG B NH2 1 
ATOM   5726  N N   . GLU B 1 332 ? 97.768  73.849  142.082 1.00 93.67 ? 332 GLU B N   1 
ATOM   5727  C CA  . GLU B 1 332 ? 97.864  73.641  143.522 1.00 93.67 ? 332 GLU B CA  1 
ATOM   5728  C C   . GLU B 1 332 ? 97.077  74.701  144.286 1.00 93.67 ? 332 GLU B C   1 
ATOM   5729  O O   . GLU B 1 332 ? 96.245  74.379  145.138 1.00 93.67 ? 332 GLU B O   1 
ATOM   5730  C CB  . GLU B 1 332 ? 99.337  73.619  143.950 1.00 93.67 ? 332 GLU B CB  1 
ATOM   5731  C CG  . GLU B 1 332 ? 100.156 74.844  143.564 1.00 93.67 ? 332 GLU B CG  1 
ATOM   5732  C CD  . GLU B 1 332 ? 100.657 74.797  142.135 1.00 93.67 ? 332 GLU B CD  1 
ATOM   5733  O OE1 . GLU B 1 332 ? 100.125 73.999  141.337 1.00 93.67 ? 332 GLU B OE1 1 
ATOM   5734  O OE2 . GLU B 1 332 ? 101.588 75.562  141.811 1.00 93.67 ? 332 GLU B OE2 1 
ATOM   5735  N N   . ASN B 1 333 ? 97.325  75.970  143.987 1.00 88.64 ? 333 ASN B N   1 
ATOM   5736  C CA  . ASN B 1 333 ? 96.611  77.081  144.590 1.00 88.64 ? 333 ASN B CA  1 
ATOM   5737  C C   . ASN B 1 333 ? 96.172  78.028  143.484 1.00 88.64 ? 333 ASN B C   1 
ATOM   5738  O O   . ASN B 1 333 ? 96.343  77.754  142.295 1.00 88.64 ? 333 ASN B O   1 
ATOM   5739  C CB  . ASN B 1 333 ? 97.474  77.811  145.627 1.00 88.64 ? 333 ASN B CB  1 
ATOM   5740  C CG  . ASN B 1 333 ? 98.889  78.043  145.148 1.00 88.64 ? 333 ASN B CG  1 
ATOM   5741  O OD1 . ASN B 1 333 ? 99.144  78.130  143.950 1.00 88.64 ? 333 ASN B OD1 1 
ATOM   5742  N ND2 . ASN B 1 333 ? 99.820  78.140  146.086 1.00 88.64 ? 333 ASN B ND2 1 
ATOM   5743  N N   . ASN B 1 334 ? 95.599  79.153  143.879 1.00 82.14 ? 334 ASN B N   1 
ATOM   5744  C CA  . ASN B 1 334 ? 95.059  80.113  142.935 1.00 82.14 ? 334 ASN B CA  1 
ATOM   5745  C C   . ASN B 1 334 ? 95.584  81.500  143.254 1.00 82.14 ? 334 ASN B C   1 
ATOM   5746  O O   . ASN B 1 334 ? 95.540  81.936  144.410 1.00 82.14 ? 334 ASN B O   1 
ATOM   5747  C CB  . ASN B 1 334 ? 93.540  80.074  142.968 1.00 82.14 ? 334 ASN B CB  1 
ATOM   5748  C CG  . ASN B 1 334 ? 93.005  78.764  142.470 1.00 82.14 ? 334 ASN B CG  1 
ATOM   5749  O OD1 . ASN B 1 334 ? 93.404  78.289  141.412 1.00 82.14 ? 334 ASN B OD1 1 
ATOM   5750  N ND2 . ASN B 1 334 ? 92.140  78.141  143.247 1.00 82.14 ? 334 ASN B ND2 1 
ATOM   5751  N N   . HIS B 1 335 ? 96.081  82.182  142.226 1.00 75.73 ? 335 HIS B N   1 
ATOM   5752  C CA  . HIS B 1 335 ? 96.741  83.474  142.374 1.00 75.73 ? 335 HIS B CA  1 
ATOM   5753  C C   . HIS B 1 335 ? 95.715  84.586  142.193 1.00 75.73 ? 335 HIS B C   1 
ATOM   5754  O O   . HIS B 1 335 ? 95.171  84.778  141.095 1.00 75.73 ? 335 HIS B O   1 
ATOM   5755  C CB  . HIS B 1 335 ? 97.873  83.607  141.365 1.00 75.73 ? 335 HIS B CB  1 
ATOM   5756  C CG  . HIS B 1 335 ? 98.896  84.627  141.739 1.00 75.73 ? 335 HIS B CG  1 
ATOM   5757  N ND1 . HIS B 1 335 ? 98.650  85.979  141.682 1.00 75.73 ? 335 HIS B ND1 1 
ATOM   5758  C CD2 . HIS B 1 335 ? 100.178 84.494  142.147 1.00 75.73 ? 335 HIS B CD2 1 
ATOM   5759  C CE1 . HIS B 1 335 ? 99.733  86.636  142.054 1.00 75.73 ? 335 HIS B CE1 1 
ATOM   5760  N NE2 . HIS B 1 335 ? 100.674 85.759  142.340 1.00 75.73 ? 335 HIS B NE2 1 
ATOM   5761  N N   . ILE B 1 336 ? 95.449  85.317  143.271 1.00 73.47 ? 336 ILE B N   1 
ATOM   5762  C CA  . ILE B 1 336 ? 94.499  86.413  143.254 1.00 73.47 ? 336 ILE B CA  1 
ATOM   5763  C C   . ILE B 1 336 ? 95.206  87.675  143.714 1.00 73.47 ? 336 ILE B C   1 
ATOM   5764  O O   . ILE B 1 336 ? 96.204  87.633  144.441 1.00 73.47 ? 336 ILE B O   1 
ATOM   5765  C CB  . ILE B 1 336 ? 93.283  86.120  144.144 1.00 73.47 ? 336 ILE B CB  1 
ATOM   5766  C CG1 . ILE B 1 336 ? 93.669  86.223  145.610 1.00 73.47 ? 336 ILE B CG1 1 
ATOM   5767  C CG2 . ILE B 1 336 ? 92.783  84.733  143.886 1.00 73.47 ? 336 ILE B CG2 1 
ATOM   5768  C CD1 . ILE B 1 336 ? 92.498  86.114  146.528 1.00 73.47 ? 336 ILE B CD1 1 
ATOM   5769  N N   . GLN B 1 337 ? 94.680  88.805  143.273 1.00 71.14 ? 337 GLN B N   1 
ATOM   5770  C CA  . GLN B 1 337 ? 95.173  90.101  143.703 1.00 71.14 ? 337 GLN B CA  1 
ATOM   5771  C C   . GLN B 1 337 ? 94.006  90.880  144.277 1.00 71.14 ? 337 GLN B C   1 
ATOM   5772  O O   . GLN B 1 337 ? 92.851  90.586  143.988 1.00 71.14 ? 337 GLN B O   1 
ATOM   5773  C CB  . GLN B 1 337 ? 95.837  90.857  142.554 1.00 71.14 ? 337 GLN B CB  1 
ATOM   5774  C CG  . GLN B 1 337 ? 97.054  90.141  142.008 1.00 71.14 ? 337 GLN B CG  1 
ATOM   5775  C CD  . GLN B 1 337 ? 97.540  90.722  140.702 1.00 71.14 ? 337 GLN B CD  1 
ATOM   5776  O OE1 . GLN B 1 337 ? 96.778  91.330  139.967 1.00 71.14 ? 337 GLN B OE1 1 
ATOM   5777  N NE2 . GLN B 1 337 ? 98.822  90.544  140.413 1.00 71.14 ? 337 GLN B NE2 1 
ATOM   5778  N N   . ILE B 1 338 ? 94.295  91.869  145.111 1.00 69.36 ? 338 ILE B N   1 
ATOM   5779  C CA  . ILE B 1 338 ? 93.233  92.554  145.828 1.00 69.36 ? 338 ILE B CA  1 
ATOM   5780  C C   . ILE B 1 338 ? 93.607  94.014  146.014 1.00 69.36 ? 338 ILE B C   1 
ATOM   5781  O O   . ILE B 1 338 ? 94.781  94.365  146.156 1.00 69.36 ? 338 ILE B O   1 
ATOM   5782  C CB  . ILE B 1 338 ? 92.945  91.869  147.174 1.00 69.36 ? 338 ILE B CB  1 
ATOM   5783  C CG1 . ILE B 1 338 ? 91.675  92.426  147.797 1.00 69.36 ? 338 ILE B CG1 1 
ATOM   5784  C CG2 . ILE B 1 338 ? 94.112  92.026  148.092 1.00 69.36 ? 338 ILE B CG2 1 
ATOM   5785  C CD1 . ILE B 1 338 ? 90.461  92.197  146.970 1.00 69.36 ? 338 ILE B CD1 1 
ATOM   5786  N N   . ASN B 1 339 ? 92.583  94.865  146.003 1.00 69.21 ? 339 ASN B N   1 
ATOM   5787  C CA  . ASN B 1 339 ? 92.765  96.310  146.001 1.00 69.21 ? 339 ASN B CA  1 
ATOM   5788  C C   . ASN B 1 339 ? 91.570  96.946  146.693 1.00 69.21 ? 339 ASN B C   1 
ATOM   5789  O O   . ASN B 1 339 ? 90.455  96.849  146.192 1.00 69.21 ? 339 ASN B O   1 
ATOM   5790  C CB  . ASN B 1 339 ? 92.896  96.807  144.569 1.00 69.21 ? 339 ASN B CB  1 
ATOM   5791  C CG  . ASN B 1 339 ? 93.155  98.274  144.485 1.00 69.21 ? 339 ASN B CG  1 
ATOM   5792  O OD1 . ASN B 1 339 ? 92.258  99.089  144.695 1.00 69.21 ? 339 ASN B OD1 1 
ATOM   5793  N ND2 . ASN B 1 339 ? 94.387  98.631  144.153 1.00 69.21 ? 339 ASN B ND2 1 
ATOM   5794  N N   . TRP B 1 340 ? 91.796  97.589  147.831 1.00 70.00 ? 340 TRP B N   1 
ATOM   5795  C CA  . TRP B 1 340 ? 90.773  98.367  148.517 1.00 70.00 ? 340 TRP B CA  1 
ATOM   5796  C C   . TRP B 1 340 ? 91.010  99.840  148.242 1.00 70.00 ? 340 TRP B C   1 
ATOM   5797  O O   . TRP B 1 340 ? 92.118  100.242 147.895 1.00 70.00 ? 340 TRP B O   1 
ATOM   5798  C CB  . TRP B 1 340 ? 90.810  98.146  150.025 1.00 70.00 ? 340 TRP B CB  1 
ATOM   5799  C CG  . TRP B 1 340 ? 90.703  96.737  150.409 1.00 70.00 ? 340 TRP B CG  1 
ATOM   5800  C CD1 . TRP B 1 340 ? 89.566  96.026  150.605 1.00 70.00 ? 340 TRP B CD1 1 
ATOM   5801  C CD2 . TRP B 1 340 ? 91.785  95.850  150.659 1.00 70.00 ? 340 TRP B CD2 1 
ATOM   5802  N NE1 . TRP B 1 340 ? 89.877  94.739  150.955 1.00 70.00 ? 340 TRP B NE1 1 
ATOM   5803  C CE2 . TRP B 1 340 ? 91.239  94.614  150.996 1.00 70.00 ? 340 TRP B CE2 1 
ATOM   5804  C CE3 . TRP B 1 340 ? 93.169  95.984  150.623 1.00 70.00 ? 340 TRP B CE3 1 
ATOM   5805  C CZ2 . TRP B 1 340 ? 92.028  93.516  151.298 1.00 70.00 ? 340 TRP B CZ2 1 
ATOM   5806  C CZ3 . TRP B 1 340 ? 93.944  94.899  150.920 1.00 70.00 ? 340 TRP B CZ3 1 
ATOM   5807  C CH2 . TRP B 1 340 ? 93.377  93.683  151.254 1.00 70.00 ? 340 TRP B CH2 1 
ATOM   5808  N N   . GLU B 1 341 ? 89.971  100.647 148.409 1.00 73.87 ? 341 GLU B N   1 
ATOM   5809  C CA  . GLU B 1 341 ? 90.127  102.081 148.217 1.00 73.87 ? 341 GLU B CA  1 
ATOM   5810  C C   . GLU B 1 341 ? 89.334  102.854 149.256 1.00 73.87 ? 341 GLU B C   1 
ATOM   5811  O O   . GLU B 1 341 ? 88.246  102.436 149.667 1.00 73.87 ? 341 GLU B O   1 
ATOM   5812  C CB  . GLU B 1 341 ? 89.715  102.520 146.811 1.00 73.87 ? 341 GLU B CB  1 
ATOM   5813  C CG  . GLU B 1 341 ? 88.235  102.622 146.541 1.00 73.87 ? 341 GLU B CG  1 
ATOM   5814  C CD  . GLU B 1 341 ? 87.959  103.573 145.402 1.00 73.87 ? 341 GLU B CD  1 
ATOM   5815  O OE1 . GLU B 1 341 ? 86.865  103.496 144.809 1.00 73.87 ? 341 GLU B OE1 1 
ATOM   5816  O OE2 . GLU B 1 341 ? 88.851  104.394 145.098 1.00 73.87 ? 341 GLU B OE2 1 
ATOM   5817  N N   . MET B 1 342 ? 89.901  103.992 149.652 1.00 75.34 ? 342 MET B N   1 
ATOM   5818  C CA  . MET B 1 342 ? 89.421  104.850 150.722 1.00 75.34 ? 342 MET B CA  1 
ATOM   5819  C C   . MET B 1 342 ? 89.145  106.232 150.151 1.00 75.34 ? 342 MET B C   1 
ATOM   5820  O O   . MET B 1 342 ? 90.028  106.836 149.523 1.00 75.34 ? 342 MET B O   1 
ATOM   5821  C CB  . MET B 1 342 ? 90.472  104.952 151.819 1.00 75.34 ? 342 MET B CB  1 
ATOM   5822  C CG  . MET B 1 342 ? 90.823  103.641 152.431 1.00 75.34 ? 342 MET B CG  1 
ATOM   5823  S SD  . MET B 1 342 ? 92.150  103.881 153.604 1.00 75.34 ? 342 MET B SD  1 
ATOM   5824  C CE  . MET B 1 342 ? 93.510  104.210 152.490 1.00 75.34 ? 342 MET B CE  1 
ATOM   5825  N N   . SER B 1 343 ? 87.934  106.731 150.378 1.00 79.52 ? 343 SER B N   1 
ATOM   5826  C CA  . SER B 1 343 ? 87.508  108.011 149.841 1.00 79.52 ? 343 SER B CA  1 
ATOM   5827  C C   . SER B 1 343 ? 87.815  109.133 150.823 1.00 79.52 ? 343 SER B C   1 
ATOM   5828  O O   . SER B 1 343 ? 88.056  108.908 152.009 1.00 79.52 ? 343 SER B O   1 
ATOM   5829  C CB  . SER B 1 343 ? 86.018  107.987 149.517 1.00 79.52 ? 343 SER B CB  1 
ATOM   5830  O OG  . SER B 1 343 ? 85.587  109.245 149.032 1.00 79.52 ? 343 SER B OG  1 
ATOM   5831  N N   . ALA B 1 344 ? 87.791  110.363 150.311 1.00 80.22 ? 344 ALA B N   1 
ATOM   5832  C CA  . ALA B 1 344 ? 88.134  111.535 151.108 1.00 80.22 ? 344 ALA B CA  1 
ATOM   5833  C C   . ALA B 1 344 ? 86.955  112.098 151.882 1.00 80.22 ? 344 ALA B C   1 
ATOM   5834  O O   . ALA B 1 344 ? 87.129  112.556 153.016 1.00 80.22 ? 344 ALA B O   1 
ATOM   5835  C CB  . ALA B 1 344 ? 88.714  112.629 150.210 1.00 80.22 ? 344 ALA B CB  1 
ATOM   5836  N N   . LYS B 1 345 ? 85.763  112.070 151.304 1.00 85.81 ? 345 LYS B N   1 
ATOM   5837  C CA  . LYS B 1 345 ? 84.616  112.700 151.934 1.00 85.81 ? 345 LYS B CA  1 
ATOM   5838  C C   . LYS B 1 345 ? 83.890  111.780 152.907 1.00 85.81 ? 345 LYS B C   1 
ATOM   5839  O O   . LYS B 1 345 ? 83.217  112.272 153.817 1.00 85.81 ? 345 LYS B O   1 
ATOM   5840  C CB  . LYS B 1 345 ? 83.640  113.191 150.863 1.00 85.81 ? 345 LYS B CB  1 
ATOM   5841  C CG  . LYS B 1 345 ? 83.048  112.079 150.023 1.00 85.81 ? 345 LYS B CG  1 
ATOM   5842  C CD  . LYS B 1 345 ? 82.116  112.626 148.961 1.00 85.81 ? 345 LYS B CD  1 
ATOM   5843  C CE  . LYS B 1 345 ? 81.420  111.500 148.214 1.00 85.81 ? 345 LYS B CE  1 
ATOM   5844  N NZ  . LYS B 1 345 ? 80.488  110.743 149.097 1.00 85.81 ? 345 LYS B NZ  1 
ATOM   5845  N N   . ASP B 1 346 ? 84.003  110.467 152.745 1.00 87.43 ? 346 ASP B N   1 
ATOM   5846  C CA  . ASP B 1 346 ? 83.247  109.530 153.559 1.00 87.43 ? 346 ASP B CA  1 
ATOM   5847  C C   . ASP B 1 346 ? 84.183  108.595 154.313 1.00 87.43 ? 346 ASP B C   1 
ATOM   5848  O O   . ASP B 1 346 ? 85.393  108.561 154.081 1.00 87.43 ? 346 ASP B O   1 
ATOM   5849  C CB  . ASP B 1 346 ? 82.277  108.708 152.702 1.00 87.43 ? 346 ASP B CB  1 
ATOM   5850  C CG  . ASP B 1 346 ? 81.156  109.544 152.131 1.00 87.43 ? 346 ASP B CG  1 
ATOM   5851  O OD1 . ASP B 1 346 ? 81.020  110.712 152.543 1.00 87.43 ? 346 ASP B OD1 1 
ATOM   5852  O OD2 . ASP B 1 346 ? 80.406  109.031 151.276 1.00 87.43 ? 346 ASP B OD2 1 
ATOM   5853  N N   . SER B 1 347 ? 83.589  107.837 155.234 1.00 86.46 ? 347 SER B N   1 
ATOM   5854  C CA  . SER B 1 347 ? 84.292  106.785 155.964 1.00 86.46 ? 347 SER B CA  1 
ATOM   5855  C C   . SER B 1 347 ? 83.983  105.428 155.335 1.00 86.46 ? 347 SER B C   1 
ATOM   5856  O O   . SER B 1 347 ? 83.373  104.545 155.935 1.00 86.46 ? 347 SER B O   1 
ATOM   5857  C CB  . SER B 1 347 ? 83.900  106.809 157.437 1.00 86.46 ? 347 SER B CB  1 
ATOM   5858  O OG  . SER B 1 347 ? 84.228  108.049 158.030 1.00 86.46 ? 347 SER B OG  1 
ATOM   5859  N N   . SER B 1 348 ? 84.421  105.274 154.092 1.00 83.25 ? 348 SER B N   1 
ATOM   5860  C CA  . SER B 1 348 ? 84.149  104.065 153.336 1.00 83.25 ? 348 SER B CA  1 
ATOM   5861  C C   . SER B 1 348 ? 85.439  103.540 152.732 1.00 83.25 ? 348 SER B C   1 
ATOM   5862  O O   . SER B 1 348 ? 86.366  104.306 152.461 1.00 83.25 ? 348 SER B O   1 
ATOM   5863  C CB  . SER B 1 348 ? 83.122  104.319 152.230 1.00 83.25 ? 348 SER B CB  1 
ATOM   5864  O OG  . SER B 1 348 ? 82.988  103.184 151.395 1.00 83.25 ? 348 SER B OG  1 
ATOM   5865  N N   . VAL B 1 349 ? 85.491  102.227 152.537 1.00 76.76 ? 349 VAL B N   1 
ATOM   5866  C CA  . VAL B 1 349 ? 86.600  101.563 151.865 1.00 76.76 ? 349 VAL B CA  1 
ATOM   5867  C C   . VAL B 1 349 ? 86.059  100.318 151.187 1.00 76.76 ? 349 VAL B C   1 
ATOM   5868  O O   . VAL B 1 349 ? 85.329  99.536  151.803 1.00 76.76 ? 349 VAL B O   1 
ATOM   5869  C CB  . VAL B 1 349 ? 87.738  101.226 152.840 1.00 76.76 ? 349 VAL B CB  1 
ATOM   5870  C CG1 . VAL B 1 349 ? 87.196  100.495 154.027 1.00 76.76 ? 349 VAL B CG1 1 
ATOM   5871  C CG2 . VAL B 1 349 ? 88.784  100.383 152.147 1.00 76.76 ? 349 VAL B CG2 1 
ATOM   5872  N N   . ALA B 1 350 ? 86.393  100.148 149.911 1.00 75.50 ? 350 ALA B N   1 
ATOM   5873  C CA  . ALA B 1 350 ? 85.763  99.113  149.100 1.00 75.50 ? 350 ALA B CA  1 
ATOM   5874  C C   . ALA B 1 350 ? 86.804  98.226  148.429 1.00 75.50 ? 350 ALA B C   1 
ATOM   5875  O O   . ALA B 1 350 ? 87.886  98.700  148.070 1.00 75.50 ? 350 ALA B O   1 
ATOM   5876  C CB  . ALA B 1 350 ? 84.848  99.733  148.032 1.00 75.50 ? 350 ALA B CB  1 
ATOM   5877  N N   . PRO B 1 351 ? 86.501  96.935  148.245 1.00 71.49 ? 351 PRO B N   1 
ATOM   5878  C CA  . PRO B 1 351 ? 87.478  96.021  147.651 1.00 71.49 ? 351 PRO B CA  1 
ATOM   5879  C C   . PRO B 1 351 ? 87.321  95.828  146.149 1.00 71.49 ? 351 PRO B C   1 
ATOM   5880  O O   . PRO B 1 351 ? 86.338  96.260  145.541 1.00 71.49 ? 351 PRO B O   1 
ATOM   5881  C CB  . PRO B 1 351 ? 87.205  94.721  148.402 1.00 71.49 ? 351 PRO B CB  1 
ATOM   5882  C CG  . PRO B 1 351 ? 85.736  94.756  148.611 1.00 71.49 ? 351 PRO B CG  1 
ATOM   5883  C CD  . PRO B 1 351 ? 85.315  96.206  148.716 1.00 71.49 ? 351 PRO B CD  1 
ATOM   5884  N N   . LYS B 1 352 ? 88.311  95.165  145.556 1.00 69.43 ? 352 LYS B N   1 
ATOM   5885  C CA  . LYS B 1 352 ? 88.349  94.869  144.126 1.00 69.43 ? 352 LYS B CA  1 
ATOM   5886  C C   . LYS B 1 352 ? 89.332  93.727  143.923 1.00 69.43 ? 352 LYS B C   1 
ATOM   5887  O O   . LYS B 1 352 ? 90.526  93.876  144.207 1.00 69.43 ? 352 LYS B O   1 
ATOM   5888  C CB  . LYS B 1 352 ? 88.762  96.095  143.331 1.00 69.43 ? 352 LYS B CB  1 
ATOM   5889  C CG  . LYS B 1 352 ? 89.055  95.854  141.875 1.00 69.43 ? 352 LYS B CG  1 
ATOM   5890  C CD  . LYS B 1 352 ? 89.481  97.152  141.245 1.00 69.43 ? 352 LYS B CD  1 
ATOM   5891  C CE  . LYS B 1 352 ? 90.083  96.952  139.884 1.00 69.43 ? 352 LYS B CE  1 
ATOM   5892  N NZ  . LYS B 1 352 ? 90.602  98.235  139.346 1.00 69.43 ? 352 LYS B NZ  1 
ATOM   5893  N N   . LEU B 1 353 ? 88.830  92.600  143.441 1.00 70.39 ? 353 LEU B N   1 
ATOM   5894  C CA  . LEU B 1 353 ? 89.561  91.348  143.363 1.00 70.39 ? 353 LEU B CA  1 
ATOM   5895  C C   . LEU B 1 353 ? 89.989  91.069  141.927 1.00 70.39 ? 353 LEU B C   1 
ATOM   5896  O O   . LEU B 1 353 ? 89.320  91.468  140.976 1.00 70.39 ? 353 LEU B O   1 
ATOM   5897  C CB  . LEU B 1 353 ? 88.673  90.218  143.890 1.00 70.39 ? 353 LEU B CB  1 
ATOM   5898  C CG  . LEU B 1 353 ? 89.067  88.748  143.875 1.00 70.39 ? 353 LEU B CG  1 
ATOM   5899  C CD1 . LEU B 1 353 ? 90.472  88.558  144.356 1.00 70.39 ? 353 LEU B CD1 1 
ATOM   5900  C CD2 . LEU B 1 353 ? 88.124  88.014  144.776 1.00 70.39 ? 353 LEU B CD2 1 
ATOM   5901  N N   . TYR B 1 354 ? 91.131  90.408  141.773 1.00 69.93 ? 354 TYR B N   1 
ATOM   5902  C CA  . TYR B 1 354 ? 91.607  89.945  140.479 1.00 69.93 ? 354 TYR B CA  1 
ATOM   5903  C C   . TYR B 1 354 ? 91.841  88.450  140.561 1.00 69.93 ? 354 TYR B C   1 
ATOM   5904  O O   . TYR B 1 354 ? 92.395  87.965  141.554 1.00 69.93 ? 354 TYR B O   1 
ATOM   5905  C CB  . TYR B 1 354 ? 92.949  90.562  140.040 1.00 69.93 ? 354 TYR B CB  1 
ATOM   5906  C CG  . TYR B 1 354 ? 93.049  92.061  139.921 1.00 69.93 ? 354 TYR B CG  1 
ATOM   5907  C CD1 . TYR B 1 354 ? 91.971  92.878  140.167 1.00 69.93 ? 354 TYR B CD1 1 
ATOM   5908  C CD2 . TYR B 1 354 ? 94.242  92.652  139.526 1.00 69.93 ? 354 TYR B CD2 1 
ATOM   5909  C CE1 . TYR B 1 354 ? 92.081  94.239  140.053 1.00 69.93 ? 354 TYR B CE1 1 
ATOM   5910  C CE2 . TYR B 1 354 ? 94.363  94.009  139.402 1.00 69.93 ? 354 TYR B CE2 1 
ATOM   5911  C CZ  . TYR B 1 354 ? 93.275  94.803  139.666 1.00 69.93 ? 354 TYR B CZ  1 
ATOM   5912  O OH  . TYR B 1 354 ? 93.367  96.171  139.551 1.00 69.93 ? 354 TYR B OH  1 
ATOM   5913  N N   . LEU B 1 355 ? 91.477  87.734  139.503 1.00 67.54 ? 355 LEU B N   1 
ATOM   5914  C CA  . LEU B 1 355 ? 91.982  86.388  139.281 1.00 67.54 ? 355 LEU B CA  1 
ATOM   5915  C C   . LEU B 1 355 ? 93.028  86.457  138.181 1.00 67.54 ? 355 LEU B C   1 
ATOM   5916  O O   . LEU B 1 355 ? 92.741  86.946  137.080 1.00 67.54 ? 355 LEU B O   1 
ATOM   5917  C CB  . LEU B 1 355 ? 90.869  85.420  138.895 1.00 67.54 ? 355 LEU B CB  1 
ATOM   5918  C CG  . LEU B 1 355 ? 89.723  85.275  139.882 1.00 67.54 ? 355 LEU B CG  1 
ATOM   5919  C CD1 . LEU B 1 355 ? 88.940  84.012  139.591 1.00 67.54 ? 355 LEU B CD1 1 
ATOM   5920  C CD2 . LEU B 1 355 ? 90.252  85.260  141.288 1.00 67.54 ? 355 LEU B CD2 1 
ATOM   5921  N N   . THR B 1 356 ? 94.239  85.989  138.476 1.00 65.19 ? 356 THR B N   1 
ATOM   5922  C CA  . THR B 1 356 ? 95.272  85.943  137.457 1.00 65.19 ? 356 THR B CA  1 
ATOM   5923  C C   . THR B 1 356 ? 95.046  84.739  136.554 1.00 65.19 ? 356 THR B C   1 
ATOM   5924  O O   . THR B 1 356 ? 94.880  83.615  137.035 1.00 65.19 ? 356 THR B O   1 
ATOM   5925  C CB  . THR B 1 356 ? 96.648  85.880  138.102 1.00 65.19 ? 356 THR B CB  1 
ATOM   5926  O OG1 . THR B 1 356 ? 96.773  86.952  139.039 1.00 65.19 ? 356 THR B OG1 1 
ATOM   5927  C CG2 . THR B 1 356 ? 97.722  86.008  137.055 1.00 65.19 ? 356 THR B CG2 1 
ATOM   5928  N N   . VAL B 1 357 ? 95.017  84.979  135.245 1.00 66.27 ? 357 VAL B N   1 
ATOM   5929  C CA  . VAL B 1 357 ? 94.742  83.956  134.247 1.00 66.27 ? 357 VAL B CA  1 
ATOM   5930  C C   . VAL B 1 357 ? 95.869  83.858  133.223 1.00 66.27 ? 357 VAL B C   1 
ATOM   5931  O O   . VAL B 1 357 ? 95.664  83.370  132.128 1.00 66.27 ? 357 VAL B O   1 
ATOM   5932  C CB  . VAL B 1 357 ? 93.389  84.205  133.556 1.00 66.27 ? 357 VAL B CB  1 
ATOM   5933  C CG1 . VAL B 1 357 ? 92.308  84.357  134.584 1.00 66.27 ? 357 VAL B CG1 1 
ATOM   5934  C CG2 . VAL B 1 357 ? 93.449  85.439  132.693 1.00 66.27 ? 357 VAL B CG2 1 
ATOM   5935  N N   . ILE B 1 358 ? 97.069  84.308  133.588 1.00 67.98 ? 358 ILE B N   1 
ATOM   5936  C CA  . ILE B 1 358 ? 98.167  84.405  132.633 1.00 67.98 ? 358 ILE B CA  1 
ATOM   5937  C C   . ILE B 1 358 ? 98.438  83.076  131.944 1.00 67.98 ? 358 ILE B C   1 
ATOM   5938  O O   . ILE B 1 358 ? 98.911  83.046  130.801 1.00 67.98 ? 358 ILE B O   1 
ATOM   5939  C CB  . ILE B 1 358 ? 99.423  84.944  133.343 1.00 67.98 ? 358 ILE B CB  1 
ATOM   5940  C CG1 . ILE B 1 358 ? 100.576 85.099  132.359 1.00 67.98 ? 358 ILE B CG1 1 
ATOM   5941  C CG2 . ILE B 1 358 ? 99.808  84.056  134.490 1.00 67.98 ? 358 ILE B CG2 1 
ATOM   5942  C CD1 . ILE B 1 358 ? 101.736 85.866  132.907 1.00 67.98 ? 358 ILE B CD1 1 
ATOM   5943  N N   . GLU B 1 359 ? 98.132  81.960  132.604 1.00 71.95 ? 359 GLU B N   1 
ATOM   5944  C CA  . GLU B 1 359 ? 98.473  80.644  132.084 1.00 71.95 ? 359 GLU B CA  1 
ATOM   5945  C C   . GLU B 1 359 ? 97.259  79.746  131.914 1.00 71.95 ? 359 GLU B C   1 
ATOM   5946  O O   . GLU B 1 359 ? 97.272  78.605  132.377 1.00 71.95 ? 359 GLU B O   1 
ATOM   5947  C CB  . GLU B 1 359 ? 99.505  79.973  132.983 1.00 71.95 ? 359 GLU B CB  1 
ATOM   5948  C CG  . GLU B 1 359 ? 100.856 80.663  132.969 1.00 71.95 ? 359 GLU B CG  1 
ATOM   5949  C CD  . GLU B 1 359 ? 101.528 80.603  131.609 1.00 71.95 ? 359 GLU B CD  1 
ATOM   5950  O OE1 . GLU B 1 359 ? 101.302 79.622  130.871 1.00 71.95 ? 359 GLU B OE1 1 
ATOM   5951  O OE2 . GLU B 1 359 ? 102.289 81.535  131.277 1.00 71.95 ? 359 GLU B OE2 1 
ATOM   5952  N N   . ASP B 1 360 ? 96.208  80.237  131.278 1.00 77.60 ? 360 ASP B N   1 
ATOM   5953  C CA  . ASP B 1 360 ? 95.026  79.438  131.017 1.00 77.60 ? 360 ASP B CA  1 
ATOM   5954  C C   . ASP B 1 360 ? 94.805  79.298  129.512 1.00 77.60 ? 360 ASP B C   1 
ATOM   5955  O O   . ASP B 1 360 ? 95.606  79.748  128.691 1.00 77.60 ? 360 ASP B O   1 
ATOM   5956  C CB  . ASP B 1 360 ? 93.804  80.061  131.689 1.00 77.60 ? 360 ASP B CB  1 
ATOM   5957  C CG  . ASP B 1 360 ? 93.889  80.031  133.197 1.00 77.60 ? 360 ASP B CG  1 
ATOM   5958  O OD1 . ASP B 1 360 ? 94.623  79.181  133.737 1.00 77.60 ? 360 ASP B OD1 1 
ATOM   5959  O OD2 . ASP B 1 360 ? 93.195  80.837  133.848 1.00 77.60 ? 360 ASP B OD2 1 
ATOM   5960  N N   . TYR B 1 361 ? 93.694  78.661  129.149 1.00 80.70 ? 361 TYR B N   1 
ATOM   5961  C CA  . TYR B 1 361 ? 93.283  78.569  127.755 1.00 80.70 ? 361 TYR B CA  1 
ATOM   5962  C C   . TYR B 1 361 ? 92.589  79.858  127.345 1.00 80.70 ? 361 TYR B C   1 
ATOM   5963  O O   . TYR B 1 361 ? 91.499  80.161  127.840 1.00 80.70 ? 361 TYR B O   1 
ATOM   5964  C CB  . TYR B 1 361 ? 92.343  77.387  127.544 1.00 80.70 ? 361 TYR B CB  1 
ATOM   5965  C CG  . TYR B 1 361 ? 93.042  76.066  127.459 1.00 80.70 ? 361 TYR B CG  1 
ATOM   5966  C CD1 . TYR B 1 361 ? 93.529  75.600  126.252 1.00 80.70 ? 361 TYR B CD1 1 
ATOM   5967  C CD2 . TYR B 1 361 ? 93.227  75.287  128.586 1.00 80.70 ? 361 TYR B CD2 1 
ATOM   5968  C CE1 . TYR B 1 361 ? 94.176  74.394  126.167 1.00 80.70 ? 361 TYR B CE1 1 
ATOM   5969  C CE2 . TYR B 1 361 ? 93.870  74.077  128.511 1.00 80.70 ? 361 TYR B CE2 1 
ATOM   5970  C CZ  . TYR B 1 361 ? 94.346  73.636  127.299 1.00 80.70 ? 361 TYR B CZ  1 
ATOM   5971  O OH  . TYR B 1 361 ? 94.991  72.427  127.214 1.00 80.70 ? 361 TYR B OH  1 
ATOM   5972  N N   . ASP B 1 362 ? 93.215  80.616  126.439 1.00 75.61 ? 362 ASP B N   1 
ATOM   5973  C CA  . ASP B 1 362 ? 92.565  81.817  125.937 1.00 75.61 ? 362 ASP B CA  1 
ATOM   5974  C C   . ASP B 1 362 ? 91.188  81.493  125.400 1.00 75.61 ? 362 ASP B C   1 
ATOM   5975  O O   . ASP B 1 362 ? 90.269  82.305  125.523 1.00 75.61 ? 362 ASP B O   1 
ATOM   5976  C CB  . ASP B 1 362 ? 93.408  82.482  124.854 1.00 75.61 ? 362 ASP B CB  1 
ATOM   5977  C CG  . ASP B 1 362 ? 94.689  83.059  125.389 1.00 75.61 ? 362 ASP B CG  1 
ATOM   5978  O OD1 . ASP B 1 362 ? 94.781  83.271  126.609 1.00 75.61 ? 362 ASP B OD1 1 
ATOM   5979  O OD2 . ASP B 1 362 ? 95.614  83.296  124.592 1.00 75.61 ? 362 ASP B OD2 1 
ATOM   5980  N N   . ALA B 1 363 ? 91.017  80.305  124.824 1.00 77.61 ? 363 ALA B N   1 
ATOM   5981  C CA  . ALA B 1 363 ? 89.683  79.869  124.439 1.00 77.61 ? 363 ALA B CA  1 
ATOM   5982  C C   . ALA B 1 363 ? 88.787  79.743  125.662 1.00 77.61 ? 363 ALA B C   1 
ATOM   5983  O O   . ALA B 1 363 ? 87.663  80.254  125.677 1.00 77.61 ? 363 ALA B O   1 
ATOM   5984  C CB  . ALA B 1 363 ? 89.760  78.547  123.680 1.00 77.61 ? 363 ALA B CB  1 
ATOM   5985  N N   . TYR B 1 364 ? 89.283  79.092  126.718 1.00 80.62 ? 364 TYR B N   1 
ATOM   5986  C CA  . TYR B 1 364 ? 88.476  78.937  127.926 1.00 80.62 ? 364 TYR B CA  1 
ATOM   5987  C C   . TYR B 1 364 ? 88.266  80.270  128.628 1.00 80.62 ? 364 TYR B C   1 
ATOM   5988  O O   . TYR B 1 364 ? 87.166  80.553  129.113 1.00 80.62 ? 364 TYR B O   1 
ATOM   5989  C CB  . TYR B 1 364 ? 89.128  77.943  128.881 1.00 80.62 ? 364 TYR B CB  1 
ATOM   5990  C CG  . TYR B 1 364 ? 88.866  76.500  128.542 1.00 80.62 ? 364 TYR B CG  1 
ATOM   5991  C CD1 . TYR B 1 364 ? 87.644  76.102  128.025 1.00 80.62 ? 364 TYR B CD1 1 
ATOM   5992  C CD2 . TYR B 1 364 ? 89.842  75.535  128.741 1.00 80.62 ? 364 TYR B CD2 1 
ATOM   5993  C CE1 . TYR B 1 364 ? 87.403  74.786  127.714 1.00 80.62 ? 364 TYR B CE1 1 
ATOM   5994  C CE2 . TYR B 1 364 ? 89.614  74.220  128.430 1.00 80.62 ? 364 TYR B CE2 1 
ATOM   5995  C CZ  . TYR B 1 364 ? 88.392  73.848  127.918 1.00 80.62 ? 364 TYR B CZ  1 
ATOM   5996  O OH  . TYR B 1 364 ? 88.159  72.530  127.608 1.00 80.62 ? 364 TYR B OH  1 
ATOM   5997  N N   . VAL B 1 365 ? 89.317  81.088  128.720 1.00 75.15 ? 365 VAL B N   1 
ATOM   5998  C CA  . VAL B 1 365 ? 89.177  82.396  129.351 1.00 75.15 ? 365 VAL B CA  1 
ATOM   5999  C C   . VAL B 1 365 ? 88.134  83.220  128.615 1.00 75.15 ? 365 VAL B C   1 
ATOM   6000  O O   . VAL B 1 365 ? 87.227  83.793  129.225 1.00 75.15 ? 365 VAL B O   1 
ATOM   6001  C CB  . VAL B 1 365 ? 90.529  83.126  129.399 1.00 75.15 ? 365 VAL B CB  1 
ATOM   6002  C CG1 . VAL B 1 365 ? 90.345  84.504  129.967 1.00 75.15 ? 365 VAL B CG1 1 
ATOM   6003  C CG2 . VAL B 1 365 ? 91.508  82.357  130.230 1.00 75.15 ? 365 VAL B CG2 1 
ATOM   6004  N N   . SER B 1 366 ? 88.254  83.293  127.291 1.00 74.10 ? 366 SER B N   1 
ATOM   6005  C CA  . SER B 1 366 ? 87.273  84.013  126.496 1.00 74.10 ? 366 SER B CA  1 
ATOM   6006  C C   . SER B 1 366 ? 85.883  83.436  126.689 1.00 74.10 ? 366 SER B C   1 
ATOM   6007  O O   . SER B 1 366 ? 84.906  84.184  126.773 1.00 74.10 ? 366 SER B O   1 
ATOM   6008  C CB  . SER B 1 366 ? 87.653  83.967  125.023 1.00 74.10 ? 366 SER B CB  1 
ATOM   6009  O OG  . SER B 1 366 ? 88.894  84.596  124.801 1.00 74.10 ? 366 SER B OG  1 
ATOM   6010  N N   . SER B 1 367 ? 85.769  82.108  126.750 1.00 76.69 ? 367 SER B N   1 
ATOM   6011  C CA  . SER B 1 367 ? 84.462  81.493  126.936 1.00 76.69 ? 367 SER B CA  1 
ATOM   6012  C C   . SER B 1 367 ? 83.836  81.933  128.249 1.00 76.69 ? 367 SER B C   1 
ATOM   6013  O O   . SER B 1 367 ? 82.660  82.316  128.293 1.00 76.69 ? 367 SER B O   1 
ATOM   6014  C CB  . SER B 1 367 ? 84.595  79.976  126.891 1.00 76.69 ? 367 SER B CB  1 
ATOM   6015  O OG  . SER B 1 367 ? 83.325  79.354  126.837 1.00 76.69 ? 367 SER B OG  1 
ATOM   6016  N N   . ALA B 1 368 ? 84.614  81.897  129.327 1.00 76.35 ? 368 ALA B N   1 
ATOM   6017  C CA  . ALA B 1 368 ? 84.093  82.305  130.624 1.00 76.35 ? 368 ALA B CA  1 
ATOM   6018  C C   . ALA B 1 368 ? 83.732  83.781  130.626 1.00 76.35 ? 368 ALA B C   1 
ATOM   6019  O O   . ALA B 1 368 ? 82.706  84.177  131.185 1.00 76.35 ? 368 ALA B O   1 
ATOM   6020  C CB  . ALA B 1 368 ? 85.109  81.996  131.719 1.00 76.35 ? 368 ALA B CB  1 
ATOM   6021  N N   . ILE B 1 369 ? 84.556  84.611  129.989 1.00 75.34 ? 369 ILE B N   1 
ATOM   6022  C CA  . ILE B 1 369 ? 84.259  86.037  129.940 1.00 75.34 ? 369 ILE B CA  1 
ATOM   6023  C C   . ILE B 1 369 ? 82.951  86.275  129.203 1.00 75.34 ? 369 ILE B C   1 
ATOM   6024  O O   . ILE B 1 369 ? 82.073  87.004  129.678 1.00 75.34 ? 369 ILE B O   1 
ATOM   6025  C CB  . ILE B 1 369 ? 85.416  86.811  129.290 1.00 75.34 ? 369 ILE B CB  1 
ATOM   6026  C CG1 . ILE B 1 369 ? 86.680  86.685  130.127 1.00 75.34 ? 369 ILE B CG1 1 
ATOM   6027  C CG2 . ILE B 1 369 ? 85.054  88.269  129.164 1.00 75.34 ? 369 ILE B CG2 1 
ATOM   6028  C CD1 . ILE B 1 369 ? 87.855  87.409  129.541 1.00 75.34 ? 369 ILE B CD1 1 
ATOM   6029  N N   . VAL B 1 370 ? 82.790  85.645  128.042 1.00 76.97 ? 370 VAL B N   1 
ATOM   6030  C CA  . VAL B 1 370 ? 81.622  85.939  127.230 1.00 76.97 ? 370 VAL B CA  1 
ATOM   6031  C C   . VAL B 1 370 ? 80.359  85.373  127.863 1.00 76.97 ? 370 VAL B C   1 
ATOM   6032  O O   . VAL B 1 370 ? 79.299  86.002  127.806 1.00 76.97 ? 370 VAL B O   1 
ATOM   6033  C CB  . VAL B 1 370 ? 81.818  85.449  125.786 1.00 76.97 ? 370 VAL B CB  1 
ATOM   6034  C CG1 . VAL B 1 370 ? 83.099  86.009  125.219 1.00 76.97 ? 370 VAL B CG1 1 
ATOM   6035  C CG2 . VAL B 1 370 ? 81.820  83.944  125.720 1.00 76.97 ? 370 VAL B CG2 1 
ATOM   6036  N N   . ASP B 1 371 ? 80.436  84.214  128.521 1.00 79.49 ? 371 ASP B N   1 
ATOM   6037  C CA  . ASP B 1 371 ? 79.189  83.720  129.096 1.00 79.49 ? 371 ASP B CA  1 
ATOM   6038  C C   . ASP B 1 371 ? 78.881  84.373  130.441 1.00 79.49 ? 371 ASP B C   1 
ATOM   6039  O O   . ASP B 1 371 ? 77.708  84.489  130.808 1.00 79.49 ? 371 ASP B O   1 
ATOM   6040  C CB  . ASP B 1 371 ? 79.187  82.190  129.202 1.00 79.49 ? 371 ASP B CB  1 
ATOM   6041  C CG  . ASP B 1 371 ? 80.375  81.643  129.946 1.00 79.49 ? 371 ASP B CG  1 
ATOM   6042  O OD1 . ASP B 1 371 ? 80.991  82.398  130.709 1.00 79.49 ? 371 ASP B OD1 1 
ATOM   6043  O OD2 . ASP B 1 371 ? 80.682  80.443  129.779 1.00 79.49 ? 371 ASP B OD2 1 
ATOM   6044  N N   . LEU B 1 372 ? 79.895  84.845  131.171 1.00 79.06 ? 372 LEU B N   1 
ATOM   6045  C CA  . LEU B 1 372 ? 79.634  85.711  132.315 1.00 79.06 ? 372 LEU B CA  1 
ATOM   6046  C C   . LEU B 1 372 ? 78.922  86.978  131.871 1.00 79.06 ? 372 LEU B C   1 
ATOM   6047  O O   . LEU B 1 372 ? 77.888  87.363  132.432 1.00 79.06 ? 372 LEU B O   1 
ATOM   6048  C CB  . LEU B 1 372 ? 80.948  86.050  133.012 1.00 79.06 ? 372 LEU B CB  1 
ATOM   6049  C CG  . LEU B 1 372 ? 80.921  87.222  133.990 1.00 79.06 ? 372 LEU B CG  1 
ATOM   6050  C CD1 . LEU B 1 372 ? 80.129  86.862  135.231 1.00 79.06 ? 372 LEU B CD1 1 
ATOM   6051  C CD2 . LEU B 1 372 ? 82.334  87.641  134.358 1.00 79.06 ? 372 LEU B CD2 1 
ATOM   6052  N N   . PHE B 1 373 ? 79.477  87.644  130.861 1.00 78.98 ? 373 PHE B N   1 
ATOM   6053  C CA  . PHE B 1 373 ? 78.803  88.776  130.250 1.00 78.98 ? 373 PHE B CA  1 
ATOM   6054  C C   . PHE B 1 373 ? 77.375  88.429  129.868 1.00 78.98 ? 373 PHE B C   1 
ATOM   6055  O O   . PHE B 1 373 ? 76.447  89.202  130.131 1.00 78.98 ? 373 PHE B O   1 
ATOM   6056  C CB  . PHE B 1 373 ? 79.584  89.223  129.024 1.00 78.98 ? 373 PHE B CB  1 
ATOM   6057  C CG  . PHE B 1 373 ? 80.716  90.137  129.333 1.00 78.98 ? 373 PHE B CG  1 
ATOM   6058  C CD1 . PHE B 1 373 ? 80.869  90.661  130.593 1.00 78.98 ? 373 PHE B CD1 1 
ATOM   6059  C CD2 . PHE B 1 373 ? 81.619  90.488  128.354 1.00 78.98 ? 373 PHE B CD2 1 
ATOM   6060  C CE1 . PHE B 1 373 ? 81.905  91.507  130.870 1.00 78.98 ? 373 PHE B CE1 1 
ATOM   6061  C CE2 . PHE B 1 373 ? 82.652  91.332  128.627 1.00 78.98 ? 373 PHE B CE2 1 
ATOM   6062  C CZ  . PHE B 1 373 ? 82.797  91.843  129.884 1.00 78.98 ? 373 PHE B CZ  1 
ATOM   6063  N N   . THR B 1 374 ? 77.176  87.268  129.247 1.00 80.89 ? 374 THR B N   1 
ATOM   6064  C CA  . THR B 1 374 ? 75.836  86.881  128.830 1.00 80.89 ? 374 THR B CA  1 
ATOM   6065  C C   . THR B 1 374 ? 74.915  86.733  130.030 1.00 80.89 ? 374 THR B C   1 
ATOM   6066  O O   . THR B 1 374 ? 73.734  87.094  129.964 1.00 80.89 ? 374 THR B O   1 
ATOM   6067  C CB  . THR B 1 374 ? 75.899  85.589  128.027 1.00 80.89 ? 374 THR B CB  1 
ATOM   6068  O OG1 . THR B 1 374 ? 76.749  85.790  126.893 1.00 80.89 ? 374 THR B OG1 1 
ATOM   6069  C CG2 . THR B 1 374 ? 74.516  85.190  127.550 1.00 80.89 ? 374 THR B CG2 1 
ATOM   6070  N N   . GLY B 1 375 ? 75.437  86.212  131.136 1.00 83.64 ? 375 GLY B N   1 
ATOM   6071  C CA  . GLY B 1 375 ? 74.678  86.236  132.374 1.00 83.64 ? 375 GLY B CA  1 
ATOM   6072  C C   . GLY B 1 375 ? 74.282  87.646  132.767 1.00 83.64 ? 375 GLY B C   1 
ATOM   6073  O O   . GLY B 1 375 ? 73.146  87.894  133.175 1.00 83.64 ? 375 GLY B O   1 
ATOM   6074  N N   . LEU B 1 376 ? 75.212  88.592  132.629 1.00 81.94 ? 376 LEU B N   1 
ATOM   6075  C CA  . LEU B 1 376 ? 74.879  89.989  132.876 1.00 81.94 ? 376 LEU B CA  1 
ATOM   6076  C C   . LEU B 1 376 ? 73.934  90.556  131.829 1.00 81.94 ? 376 LEU B C   1 
ATOM   6077  O O   . LEU B 1 376 ? 73.324  91.601  132.066 1.00 81.94 ? 376 LEU B O   1 
ATOM   6078  C CB  . LEU B 1 376 ? 76.140  90.847  132.911 1.00 81.94 ? 376 LEU B CB  1 
ATOM   6079  C CG  . LEU B 1 376 ? 76.880  90.929  134.241 1.00 81.94 ? 376 LEU B CG  1 
ATOM   6080  C CD1 . LEU B 1 376 ? 75.950  91.481  135.309 1.00 81.94 ? 376 LEU B CD1 1 
ATOM   6081  C CD2 . LEU B 1 376 ? 77.456  89.589  134.649 1.00 81.94 ? 376 LEU B CD2 1 
ATOM   6082  N N   . GLY B 1 377 ? 73.797  89.895  130.686 1.00 79.83 ? 377 GLY B N   1 
ATOM   6083  C CA  . GLY B 1 377 ? 73.086  90.498  129.586 1.00 79.83 ? 377 GLY B CA  1 
ATOM   6084  C C   . GLY B 1 377 ? 73.862  91.567  128.858 1.00 79.83 ? 377 GLY B C   1 
ATOM   6085  O O   . GLY B 1 377 ? 73.274  92.307  128.064 1.00 79.83 ? 377 GLY B O   1 
ATOM   6086  N N   . TRP B 1 378 ? 75.170  91.671  129.095 1.00 77.30 ? 378 TRP B N   1 
ATOM   6087  C CA  . TRP B 1 378 ? 76.006  92.668  128.428 1.00 77.30 ? 378 TRP B CA  1 
ATOM   6088  C C   . TRP B 1 378 ? 76.307  92.244  126.988 1.00 77.30 ? 378 TRP B C   1 
ATOM   6089  O O   . TRP B 1 378 ? 77.456  92.078  126.582 1.00 77.30 ? 378 TRP B O   1 
ATOM   6090  C CB  . TRP B 1 378 ? 77.297  92.881  129.208 1.00 77.30 ? 378 TRP B CB  1 
ATOM   6091  C CG  . TRP B 1 378 ? 77.157  93.726  130.430 1.00 77.30 ? 378 TRP B CG  1 
ATOM   6092  C CD1 . TRP B 1 378 ? 76.023  94.320  130.893 1.00 77.30 ? 378 TRP B CD1 1 
ATOM   6093  C CD2 . TRP B 1 378 ? 78.196  94.071  131.351 1.00 77.30 ? 378 TRP B CD2 1 
ATOM   6094  N NE1 . TRP B 1 378 ? 76.292  95.017  132.046 1.00 77.30 ? 378 TRP B NE1 1 
ATOM   6095  C CE2 . TRP B 1 378 ? 77.620  94.877  132.348 1.00 77.30 ? 378 TRP B CE2 1 
ATOM   6096  C CE3 . TRP B 1 378 ? 79.558  93.776  131.430 1.00 77.30 ? 378 TRP B CE3 1 
ATOM   6097  C CZ2 . TRP B 1 378 ? 78.359  95.389  133.410 1.00 77.30 ? 378 TRP B CZ2 1 
ATOM   6098  C CZ3 . TRP B 1 378 ? 80.290  94.287  132.482 1.00 77.30 ? 378 TRP B CZ3 1 
ATOM   6099  C CH2 . TRP B 1 378 ? 79.691  95.082  133.457 1.00 77.30 ? 378 TRP B CH2 1 
ATOM   6100  N N   . ALA B 1 379 ? 75.239  92.087  126.204 1.00 76.73 ? 379 ALA B N   1 
ATOM   6101  C CA  . ALA B 1 379 ? 75.395  91.587  124.842 1.00 76.73 ? 379 ALA B CA  1 
ATOM   6102  C C   . ALA B 1 379 ? 76.147  92.577  123.966 1.00 76.73 ? 379 ALA B C   1 
ATOM   6103  O O   . ALA B 1 379 ? 77.005  92.182  123.167 1.00 76.73 ? 379 ALA B O   1 
ATOM   6104  C CB  . ALA B 1 379 ? 74.030  91.272  124.239 1.00 76.73 ? 379 ALA B CB  1 
ATOM   6105  N N   . ALA B 1 380 ? 75.824  93.863  124.078 1.00 76.16 ? 380 ALA B N   1 
ATOM   6106  C CA  . ALA B 1 380 ? 76.622  94.872  123.398 1.00 76.16 ? 380 ALA B CA  1 
ATOM   6107  C C   . ALA B 1 380 ? 78.083  94.727  123.787 1.00 76.16 ? 380 ALA B C   1 
ATOM   6108  O O   . ALA B 1 380 ? 78.975  94.710  122.932 1.00 76.16 ? 380 ALA B O   1 
ATOM   6109  C CB  . ALA B 1 380 ? 76.104  96.267  123.741 1.00 76.16 ? 380 ALA B CB  1 
ATOM   6110  N N   . HIS B 1 381 ? 78.339  94.588  125.084 1.00 75.00 ? 381 HIS B N   1 
ATOM   6111  C CA  . HIS B 1 381 ? 79.694  94.331  125.542 1.00 75.00 ? 381 HIS B CA  1 
ATOM   6112  C C   . HIS B 1 381 ? 80.215  92.998  125.029 1.00 75.00 ? 381 HIS B C   1 
ATOM   6113  O O   . HIS B 1 381 ? 81.422  92.844  124.842 1.00 75.00 ? 381 HIS B O   1 
ATOM   6114  C CB  . HIS B 1 381 ? 79.737  94.367  127.063 1.00 75.00 ? 381 HIS B CB  1 
ATOM   6115  C CG  . HIS B 1 381 ? 79.472  95.722  127.642 1.00 75.00 ? 381 HIS B CG  1 
ATOM   6116  N ND1 . HIS B 1 381 ? 80.431  96.710  127.696 1.00 75.00 ? 381 HIS B ND1 1 
ATOM   6117  C CD2 . HIS B 1 381 ? 78.359  96.249  128.200 1.00 75.00 ? 381 HIS B CD2 1 
ATOM   6118  C CE1 . HIS B 1 381 ? 79.921  97.786  128.266 1.00 75.00 ? 381 HIS B CE1 1 
ATOM   6119  N NE2 . HIS B 1 381 ? 78.665  97.533  128.580 1.00 75.00 ? 381 HIS B NE2 1 
ATOM   6120  N N   . VAL B 1 382 ? 79.332  92.028  124.790 1.00 75.19 ? 382 VAL B N   1 
ATOM   6121  C CA  . VAL B 1 382 ? 79.784  90.739  124.272 1.00 75.19 ? 382 VAL B CA  1 
ATOM   6122  C C   . VAL B 1 382 ? 80.359  90.904  122.871 1.00 75.19 ? 382 VAL B C   1 
ATOM   6123  O O   . VAL B 1 382 ? 81.465  90.434  122.571 1.00 75.19 ? 382 VAL B O   1 
ATOM   6124  C CB  . VAL B 1 382 ? 78.637  89.712  124.284 1.00 75.19 ? 382 VAL B CB  1 
ATOM   6125  C CG1 . VAL B 1 382 ? 78.982  88.535  123.393 1.00 75.19 ? 382 VAL B CG1 1 
ATOM   6126  C CG2 . VAL B 1 382 ? 78.354  89.237  125.689 1.00 75.19 ? 382 VAL B CG2 1 
ATOM   6127  N N   . GLN B 1 383 ? 79.599  91.547  121.985 1.00 73.80 ? 383 GLN B N   1 
ATOM   6128  C CA  . GLN B 1 383 ? 80.104  91.807  120.645 1.00 73.80 ? 383 GLN B CA  1 
ATOM   6129  C C   . GLN B 1 383 ? 81.336  92.683  120.704 1.00 73.80 ? 383 GLN B C   1 
ATOM   6130  O O   . GLN B 1 383 ? 82.281  92.487  119.938 1.00 73.80 ? 383 GLN B O   1 
ATOM   6131  C CB  . GLN B 1 383 ? 79.030  92.464  119.783 1.00 73.80 ? 383 GLN B CB  1 
ATOM   6132  C CG  . GLN B 1 383 ? 77.731  91.692  119.741 1.00 73.80 ? 383 GLN B CG  1 
ATOM   6133  C CD  . GLN B 1 383 ? 77.954  90.214  119.535 1.00 73.80 ? 383 GLN B CD  1 
ATOM   6134  O OE1 . GLN B 1 383 ? 78.660  89.805  118.615 1.00 73.80 ? 383 GLN B OE1 1 
ATOM   6135  N NE2 . GLN B 1 383 ? 77.354  89.400  120.393 1.00 73.80 ? 383 GLN B NE2 1 
ATOM   6136  N N   . THR B 1 384 ? 81.344  93.656  121.611 1.00 70.20 ? 384 THR B N   1 
ATOM   6137  C CA  . THR B 1 384 ? 82.535  94.471  121.799 1.00 70.20 ? 384 THR B CA  1 
ATOM   6138  C C   . THR B 1 384 ? 83.743  93.597  122.097 1.00 70.20 ? 384 THR B C   1 
ATOM   6139  O O   . THR B 1 384 ? 84.791  93.723  121.455 1.00 70.20 ? 384 THR B O   1 
ATOM   6140  C CB  . THR B 1 384 ? 82.310  95.461  122.932 1.00 70.20 ? 384 THR B CB  1 
ATOM   6141  O OG1 . THR B 1 384 ? 81.000  96.019  122.821 1.00 70.20 ? 384 THR B OG1 1 
ATOM   6142  C CG2 . THR B 1 384 ? 83.322  96.580  122.850 1.00 70.20 ? 384 THR B CG2 1 
ATOM   6143  N N   . HIS B 1 385 ? 83.596  92.671  123.043 1.00 68.14 ? 385 HIS B N   1 
ATOM   6144  C CA  . HIS B 1 385 ? 84.716  91.830  123.437 1.00 68.14 ? 385 HIS B CA  1 
ATOM   6145  C C   . HIS B 1 385 ? 85.188  90.965  122.279 1.00 68.14 ? 385 HIS B C   1 
ATOM   6146  O O   . HIS B 1 385 ? 86.386  90.895  121.994 1.00 68.14 ? 385 HIS B O   1 
ATOM   6147  C CB  . HIS B 1 385 ? 84.329  90.955  124.620 1.00 68.14 ? 385 HIS B CB  1 
ATOM   6148  C CG  . HIS B 1 385 ? 85.430  90.054  125.063 1.00 68.14 ? 385 HIS B CG  1 
ATOM   6149  N ND1 . HIS B 1 385 ? 85.395  88.692  124.879 1.00 68.14 ? 385 HIS B ND1 1 
ATOM   6150  C CD2 . HIS B 1 385 ? 86.619  90.326  125.649 1.00 68.14 ? 385 HIS B CD2 1 
ATOM   6151  C CE1 . HIS B 1 385 ? 86.507  88.159  125.351 1.00 68.14 ? 385 HIS B CE1 1 
ATOM   6152  N NE2 . HIS B 1 385 ? 87.269  89.130  125.822 1.00 68.14 ? 385 HIS B NE2 1 
ATOM   6153  N N   . LYS B 1 386 ? 84.256  90.300  121.597 1.00 69.70 ? 386 LYS B N   1 
ATOM   6154  C CA  . LYS B 1 386 ? 84.649  89.403  120.511 1.00 69.70 ? 386 LYS B CA  1 
ATOM   6155  C C   . LYS B 1 386 ? 85.264  90.172  119.350 1.00 69.70 ? 386 LYS B C   1 
ATOM   6156  O O   . LYS B 1 386 ? 86.202  89.694  118.702 1.00 69.70 ? 386 LYS B O   1 
ATOM   6157  C CB  . LYS B 1 386 ? 83.450  88.590  120.032 1.00 69.70 ? 386 LYS B CB  1 
ATOM   6158  C CG  . LYS B 1 386 ? 83.139  87.387  120.889 1.00 69.70 ? 386 LYS B CG  1 
ATOM   6159  C CD  . LYS B 1 386 ? 81.710  86.942  120.691 1.00 69.70 ? 386 LYS B CD  1 
ATOM   6160  C CE  . LYS B 1 386 ? 81.584  85.454  120.894 1.00 69.70 ? 386 LYS B CE  1 
ATOM   6161  N NZ  . LYS B 1 386 ? 82.390  84.734  119.878 1.00 69.70 ? 386 LYS B NZ  1 
ATOM   6162  N N   . LYS B 1 387 ? 84.742  91.361  119.065 1.00 64.63 ? 387 LYS B N   1 
ATOM   6163  C CA  . LYS B 1 387 ? 85.290  92.173  117.992 1.00 64.63 ? 387 LYS B CA  1 
ATOM   6164  C C   . LYS B 1 387 ? 86.711  92.598  118.313 1.00 64.63 ? 387 LYS B C   1 
ATOM   6165  O O   . LYS B 1 387 ? 87.619  92.442  117.488 1.00 64.63 ? 387 LYS B O   1 
ATOM   6166  C CB  . LYS B 1 387 ? 84.395  93.387  117.770 1.00 64.63 ? 387 LYS B CB  1 
ATOM   6167  C CG  . LYS B 1 387 ? 84.923  94.380  116.779 1.00 64.63 ? 387 LYS B CG  1 
ATOM   6168  C CD  . LYS B 1 387 ? 84.227  95.708  116.945 1.00 64.63 ? 387 LYS B CD  1 
ATOM   6169  C CE  . LYS B 1 387 ? 82.733  95.526  117.082 1.00 64.63 ? 387 LYS B CE  1 
ATOM   6170  N NZ  . LYS B 1 387 ? 82.041  96.829  117.236 1.00 64.63 ? 387 LYS B NZ  1 
ATOM   6171  N N   . ILE B 1 388 ? 86.917  93.156  119.507 1.00 61.65 ? 388 ILE B N   1 
ATOM   6172  C CA  . ILE B 1 388 ? 88.264  93.520  119.926 1.00 61.65 ? 388 ILE B CA  1 
ATOM   6173  C C   . ILE B 1 388 ? 89.170  92.305  119.882 1.00 61.65 ? 388 ILE B C   1 
ATOM   6174  O O   . ILE B 1 388 ? 90.344  92.397  119.508 1.00 61.65 ? 388 ILE B O   1 
ATOM   6175  C CB  . ILE B 1 388 ? 88.235  94.152  121.327 1.00 61.65 ? 388 ILE B CB  1 
ATOM   6176  C CG1 . ILE B 1 388 ? 87.349  95.390  121.321 1.00 61.65 ? 388 ILE B CG1 1 
ATOM   6177  C CG2 . ILE B 1 388 ? 89.632  94.516  121.766 1.00 61.65 ? 388 ILE B CG2 1 
ATOM   6178  C CD1 . ILE B 1 388 ? 87.102  95.974  122.675 1.00 61.65 ? 388 ILE B CD1 1 
ATOM   6179  N N   . GLU B 1 389 ? 88.631  91.141  120.234 1.00 65.75 ? 389 GLU B N   1 
ATOM   6180  C CA  . GLU B 1 389 ? 89.414  89.917  120.207 1.00 65.75 ? 389 GLU B CA  1 
ATOM   6181  C C   . GLU B 1 389 ? 89.908  89.621  118.801 1.00 65.75 ? 389 GLU B C   1 
ATOM   6182  O O   . GLU B 1 389 ? 91.114  89.624  118.536 1.00 65.75 ? 389 GLU B O   1 
ATOM   6183  C CB  . GLU B 1 389 ? 88.566  88.764  120.730 1.00 65.75 ? 389 GLU B CB  1 
ATOM   6184  C CG  . GLU B 1 389 ? 89.369  87.632  121.306 1.00 65.75 ? 389 GLU B CG  1 
ATOM   6185  C CD  . GLU B 1 389 ? 88.497  86.483  121.729 1.00 65.75 ? 389 GLU B CD  1 
ATOM   6186  O OE1 . GLU B 1 389 ? 87.509  86.199  121.022 1.00 65.75 ? 389 GLU B OE1 1 
ATOM   6187  O OE2 . GLU B 1 389 ? 88.793  85.871  122.772 1.00 65.75 ? 389 GLU B OE2 1 
ATOM   6188  N N   . LYS B 1 390 ? 88.974  89.387  117.882 1.00 64.87 ? 390 LYS B N   1 
ATOM   6189  C CA  . LYS B 1 390 ? 89.334  88.999  116.523 1.00 64.87 ? 390 LYS B CA  1 
ATOM   6190  C C   . LYS B 1 390 ? 90.246  90.026  115.871 1.00 64.87 ? 390 LYS B C   1 
ATOM   6191  O O   . LYS B 1 390 ? 91.248  89.667  115.245 1.00 64.87 ? 390 LYS B O   1 
ATOM   6192  C CB  . LYS B 1 390 ? 88.072  88.801  115.691 1.00 64.87 ? 390 LYS B CB  1 
ATOM   6193  C CG  . LYS B 1 390 ? 88.338  88.371  114.274 1.00 64.87 ? 390 LYS B CG  1 
ATOM   6194  C CD  . LYS B 1 390 ? 87.047  88.261  113.494 1.00 64.87 ? 390 LYS B CD  1 
ATOM   6195  C CE  . LYS B 1 390 ? 86.327  89.594  113.461 1.00 64.87 ? 390 LYS B CE  1 
ATOM   6196  N NZ  . LYS B 1 390 ? 85.041  89.517  112.719 1.00 64.87 ? 390 LYS B NZ  1 
ATOM   6197  N N   . GLU B 1 391 ? 89.932  91.310  116.019 1.00 61.80 ? 391 GLU B N   1 
ATOM   6198  C CA  . GLU B 1 391 ? 90.705  92.327  115.321 1.00 61.80 ? 391 GLU B CA  1 
ATOM   6199  C C   . GLU B 1 391 ? 92.067  92.537  115.965 1.00 61.80 ? 391 GLU B C   1 
ATOM   6200  O O   . GLU B 1 391 ? 93.093  92.507  115.281 1.00 61.80 ? 391 GLU B O   1 
ATOM   6201  C CB  . GLU B 1 391 ? 89.917  93.635  115.280 1.00 61.80 ? 391 GLU B CB  1 
ATOM   6202  C CG  . GLU B 1 391 ? 88.667  93.554  114.423 1.00 61.80 ? 391 GLU B CG  1 
ATOM   6203  C CD  . GLU B 1 391 ? 87.858  94.828  114.445 1.00 61.80 ? 391 GLU B CD  1 
ATOM   6204  O OE1 . GLU B 1 391 ? 87.946  95.572  115.439 1.00 61.80 ? 391 GLU B OE1 1 
ATOM   6205  O OE2 . GLU B 1 391 ? 87.131  95.088  113.467 1.00 61.80 ? 391 GLU B OE2 1 
ATOM   6206  N N   . ALA B 1 392 ? 92.099  92.755  117.278 1.00 57.98 ? 392 ALA B N   1 
ATOM   6207  C CA  . ALA B 1 392 ? 93.344  93.076  117.955 1.00 57.98 ? 392 ALA B CA  1 
ATOM   6208  C C   . ALA B 1 392 ? 94.163  91.845  118.299 1.00 57.98 ? 392 ALA B C   1 
ATOM   6209  O O   . ALA B 1 392 ? 95.384  91.958  118.454 1.00 57.98 ? 392 ALA B O   1 
ATOM   6210  C CB  . ALA B 1 392 ? 93.057  93.867  119.225 1.00 57.98 ? 392 ALA B CB  1 
ATOM   6211  N N   . TYR B 1 393 ? 93.532  90.679  118.420 1.00 59.00 ? 393 TYR B N   1 
ATOM   6212  C CA  . TYR B 1 393 ? 94.216  89.450  118.815 1.00 59.00 ? 393 TYR B CA  1 
ATOM   6213  C C   . TYR B 1 393 ? 93.775  88.315  117.905 1.00 59.00 ? 393 TYR B C   1 
ATOM   6214  O O   . TYR B 1 393 ? 92.817  87.592  118.208 1.00 59.00 ? 393 TYR B O   1 
ATOM   6215  C CB  . TYR B 1 393 ? 93.942  89.126  120.276 1.00 59.00 ? 393 TYR B CB  1 
ATOM   6216  C CG  . TYR B 1 393 ? 94.391  90.223  121.198 1.00 59.00 ? 393 TYR B CG  1 
ATOM   6217  C CD1 . TYR B 1 393 ? 95.737  90.455  121.418 1.00 59.00 ? 393 TYR B CD1 1 
ATOM   6218  C CD2 . TYR B 1 393 ? 93.473  91.042  121.833 1.00 59.00 ? 393 TYR B CD2 1 
ATOM   6219  C CE1 . TYR B 1 393 ? 96.154  91.457  122.249 1.00 59.00 ? 393 TYR B CE1 1 
ATOM   6220  C CE2 . TYR B 1 393 ? 93.886  92.051  122.665 1.00 59.00 ? 393 TYR B CE2 1 
ATOM   6221  C CZ  . TYR B 1 393 ? 95.226  92.249  122.866 1.00 59.00 ? 393 TYR B CZ  1 
ATOM   6222  O OH  . TYR B 1 393 ? 95.644  93.249  123.696 1.00 59.00 ? 393 TYR B OH  1 
ATOM   6223  N N   . PRO B 1 394 ? 94.455  88.119  116.792 1.00 67.03 ? 394 PRO B N   1 
ATOM   6224  C CA  . PRO B 1 394 ? 94.080  87.027  115.890 1.00 67.03 ? 394 PRO B CA  1 
ATOM   6225  C C   . PRO B 1 394 ? 94.454  85.661  116.437 1.00 67.03 ? 394 PRO B C   1 
ATOM   6226  O O   . PRO B 1 394 ? 93.808  84.663  116.108 1.00 67.03 ? 394 PRO B O   1 
ATOM   6227  C CB  . PRO B 1 394 ? 94.866  87.353  114.616 1.00 67.03 ? 394 PRO B CB  1 
ATOM   6228  C CG  . PRO B 1 394 ? 96.052  88.108  115.097 1.00 67.03 ? 394 PRO B CG  1 
ATOM   6229  C CD  . PRO B 1 394 ? 95.603  88.891  116.289 1.00 67.03 ? 394 PRO B CD  1 
ATOM   6230  N N   . MET B 1 395 ? 95.490  85.617  117.281 1.00 66.50 ? 395 MET B N   1 
ATOM   6231  C CA  . MET B 1 395 ? 96.082  84.349  117.702 1.00 66.50 ? 395 MET B CA  1 
ATOM   6232  C C   . MET B 1 395 ? 95.055  83.413  118.324 1.00 66.50 ? 395 MET B C   1 
ATOM   6233  O O   . MET B 1 395 ? 95.107  82.199  118.111 1.00 66.50 ? 395 MET B O   1 
ATOM   6234  C CB  . MET B 1 395 ? 97.220  84.612  118.684 1.00 66.50 ? 395 MET B CB  1 
ATOM   6235  C CG  . MET B 1 395 ? 96.875  85.605  119.776 1.00 66.50 ? 395 MET B CG  1 
ATOM   6236  S SD  . MET B 1 395 ? 98.276  86.625  120.260 1.00 66.50 ? 395 MET B SD  1 
ATOM   6237  C CE  . MET B 1 395 ? 98.595  87.504  118.741 1.00 66.50 ? 395 MET B CE  1 
ATOM   6238  N N   . CYS B 1 396 ? 94.104  83.958  119.083 1.00 72.83 ? 396 CYS B N   1 
ATOM   6239  C CA  . CYS B 1 396 ? 93.129  83.120  119.773 1.00 72.83 ? 396 CYS B CA  1 
ATOM   6240  C C   . CYS B 1 396 ? 92.318  82.261  118.812 1.00 72.83 ? 396 CYS B C   1 
ATOM   6241  O O   . CYS B 1 396 ? 91.715  81.271  119.239 1.00 72.83 ? 396 CYS B O   1 
ATOM   6242  C CB  . CYS B 1 396 ? 92.192  83.988  120.613 1.00 72.83 ? 396 CYS B CB  1 
ATOM   6243  S SG  . CYS B 1 396 ? 91.230  85.181  119.658 1.00 72.83 ? 396 CYS B SG  1 
ATOM   6244  N N   . ASP B 1 397 ? 92.285  82.621  117.533 1.00 75.61 ? 397 ASP B N   1 
ATOM   6245  C CA  . ASP B 1 397 ? 91.647  81.814  116.505 1.00 75.61 ? 397 ASP B CA  1 
ATOM   6246  C C   . ASP B 1 397 ? 92.651  81.072  115.646 1.00 75.61 ? 397 ASP B C   1 
ATOM   6247  O O   . ASP B 1 397 ? 92.418  79.914  115.293 1.00 75.61 ? 397 ASP B O   1 
ATOM   6248  C CB  . ASP B 1 397 ? 90.769  82.691  115.614 1.00 75.61 ? 397 ASP B CB  1 
ATOM   6249  C CG  . ASP B 1 397 ? 89.639  83.333  116.377 1.00 75.61 ? 397 ASP B CG  1 
ATOM   6250  O OD1 . ASP B 1 397 ? 89.530  83.073  117.589 1.00 75.61 ? 397 ASP B OD1 1 
ATOM   6251  O OD2 . ASP B 1 397 ? 88.862  84.098  115.771 1.00 75.61 ? 397 ASP B OD2 1 
ATOM   6252  N N   . ALA B 1 398 ? 93.771  81.711  115.307 1.00 75.90 ? 398 ALA B N   1 
ATOM   6253  C CA  . ALA B 1 398 ? 94.784  81.046  114.496 1.00 75.90 ? 398 ALA B CA  1 
ATOM   6254  C C   . ALA B 1 398 ? 95.391  79.853  115.218 1.00 75.90 ? 398 ALA B C   1 
ATOM   6255  O O   . ALA B 1 398 ? 95.914  78.938  114.574 1.00 75.90 ? 398 ALA B O   1 
ATOM   6256  C CB  . ALA B 1 398 ? 95.879  82.035  114.104 1.00 75.90 ? 398 ALA B CB  1 
ATOM   6257  N N   . ASN B 1 399 ? 95.337  79.843  116.545 1.00 77.93 ? 399 ASN B N   1 
ATOM   6258  C CA  . ASN B 1 399 ? 95.908  78.773  117.348 1.00 77.93 ? 399 ASN B CA  1 
ATOM   6259  C C   . ASN B 1 399 ? 94.843  78.240  118.294 1.00 77.93 ? 399 ASN B C   1 
ATOM   6260  O O   . ASN B 1 399 ? 94.322  79.007  119.123 1.00 77.93 ? 399 ASN B O   1 
ATOM   6261  C CB  . ASN B 1 399 ? 97.118  79.282  118.130 1.00 77.93 ? 399 ASN B CB  1 
ATOM   6262  C CG  . ASN B 1 399 ? 97.957  78.167  118.701 1.00 77.93 ? 399 ASN B CG  1 
ATOM   6263  O OD1 . ASN B 1 399 ? 97.464  77.073  118.965 1.00 77.93 ? 399 ASN B OD1 1 
ATOM   6264  N ND2 . ASN B 1 399 ? 99.238  78.443  118.904 1.00 77.93 ? 399 ASN B ND2 1 
ATOM   6265  N N   . PRO B 1 400 ? 94.468  76.963  118.210 1.00 78.95 ? 400 PRO B N   1 
ATOM   6266  C CA  . PRO B 1 400 ? 93.513  76.427  119.193 1.00 78.95 ? 400 PRO B CA  1 
ATOM   6267  C C   . PRO B 1 400 ? 94.051  76.443  120.610 1.00 78.95 ? 400 PRO B C   1 
ATOM   6268  O O   . PRO B 1 400 ? 93.314  76.779  121.544 1.00 78.95 ? 400 PRO B O   1 
ATOM   6269  C CB  . PRO B 1 400 ? 93.265  74.997  118.695 1.00 78.95 ? 400 PRO B CB  1 
ATOM   6270  C CG  . PRO B 1 400 ? 93.662  75.018  117.260 1.00 78.95 ? 400 PRO B CG  1 
ATOM   6271  C CD  . PRO B 1 400 ? 94.789  75.988  117.159 1.00 78.95 ? 400 PRO B CD  1 
ATOM   6272  N N   . GLN B 1 401 ? 95.317  76.085  120.798 1.00 79.33 ? 401 GLN B N   1 
ATOM   6273  C CA  . GLN B 1 401 ? 95.962  76.146  122.107 1.00 79.33 ? 401 GLN B CA  1 
ATOM   6274  C C   . GLN B 1 401 ? 96.565  77.532  122.257 1.00 79.33 ? 401 GLN B C   1 
ATOM   6275  O O   . GLN B 1 401 ? 97.604  77.835  121.669 1.00 79.33 ? 401 GLN B O   1 
ATOM   6276  C CB  . GLN B 1 401 ? 97.022  75.063  122.243 1.00 79.33 ? 401 GLN B CB  1 
ATOM   6277  C CG  . GLN B 1 401 ? 96.487  73.657  122.095 1.00 79.33 ? 401 GLN B CG  1 
ATOM   6278  C CD  . GLN B 1 401 ? 97.590  72.629  122.064 1.00 79.33 ? 401 GLN B CD  1 
ATOM   6279  O OE1 . GLN B 1 401 ? 97.340  71.441  121.877 1.00 79.33 ? 401 GLN B OE1 1 
ATOM   6280  N NE2 . GLN B 1 401 ? 98.824  73.082  122.245 1.00 79.33 ? 401 GLN B NE2 1 
ATOM   6281  N N   . SER B 1 402 ? 95.921  78.372  123.060 1.00 76.20 ? 402 SER B N   1 
ATOM   6282  C CA  . SER B 1 402 ? 96.251  79.784  123.139 1.00 76.20 ? 402 SER B CA  1 
ATOM   6283  C C   . SER B 1 402 ? 96.206  80.257  124.583 1.00 76.20 ? 402 SER B C   1 
ATOM   6284  O O   . SER B 1 402 ? 95.239  79.995  125.300 1.00 76.20 ? 402 SER B O   1 
ATOM   6285  C CB  . SER B 1 402 ? 95.285  80.588  122.281 1.00 76.20 ? 402 SER B CB  1 
ATOM   6286  O OG  . SER B 1 402 ? 93.971  80.431  122.768 1.00 76.20 ? 402 SER B OG  1 
ATOM   6287  N N   . THR B 1 403 ? 97.254  80.965  125.002 1.00 70.50 ? 403 THR B N   1 
ATOM   6288  C CA  . THR B 1 403 ? 97.408  81.349  126.398 1.00 70.50 ? 403 THR B CA  1 
ATOM   6289  C C   . THR B 1 403 ? 97.742  82.824  126.584 1.00 70.50 ? 403 THR B C   1 
ATOM   6290  O O   . THR B 1 403 ? 97.920  83.262  127.726 1.00 70.50 ? 403 THR B O   1 
ATOM   6291  C CB  . THR B 1 403 ? 98.506  80.514  127.064 1.00 70.50 ? 403 THR B CB  1 
ATOM   6292  O OG1 . THR B 1 403 ? 99.762  80.791  126.432 1.00 70.50 ? 403 THR B OG1 1 
ATOM   6293  C CG2 . THR B 1 403 ? 98.201  79.039  126.946 1.00 70.50 ? 403 THR B CG2 1 
ATOM   6294  N N   . HIS B 1 404 ? 97.805  83.609  125.509 1.00 62.28 ? 404 HIS B N   1 
ATOM   6295  C CA  . HIS B 1 404 ? 98.567  84.848  125.524 1.00 62.28 ? 404 HIS B CA  1 
ATOM   6296  C C   . HIS B 1 404 ? 97.756  86.124  125.379 1.00 62.28 ? 404 HIS B C   1 
ATOM   6297  O O   . HIS B 1 404 ? 98.337  87.211  125.438 1.00 62.28 ? 404 HIS B O   1 
ATOM   6298  C CB  . HIS B 1 404 ? 99.628  84.805  124.425 1.00 62.28 ? 404 HIS B CB  1 
ATOM   6299  C CG  . HIS B 1 404 ? 100.795 83.944  124.769 1.00 62.28 ? 404 HIS B CG  1 
ATOM   6300  N ND1 . HIS B 1 404 ? 101.050 83.530  126.057 1.00 62.28 ? 404 HIS B ND1 1 
ATOM   6301  C CD2 . HIS B 1 404 ? 101.776 83.419  124.001 1.00 62.28 ? 404 HIS B CD2 1 
ATOM   6302  C CE1 . HIS B 1 404 ? 102.140 82.785  126.067 1.00 62.28 ? 404 HIS B CE1 1 
ATOM   6303  N NE2 . HIS B 1 404 ? 102.600 82.703  124.832 1.00 62.28 ? 404 HIS B NE2 1 
ATOM   6304  N N   . ALA B 1 405 ? 96.444  86.046  125.201 1.00 60.71 ? 405 ALA B N   1 
ATOM   6305  C CA  . ALA B 1 405 ? 95.672  87.278  125.124 1.00 60.71 ? 405 ALA B CA  1 
ATOM   6306  C C   . ALA B 1 405 ? 95.502  87.900  126.500 1.00 60.71 ? 405 ALA B C   1 
ATOM   6307  O O   . ALA B 1 405 ? 95.970  89.012  126.752 1.00 60.71 ? 405 ALA B O   1 
ATOM   6308  C CB  . ALA B 1 405 ? 94.310  87.014  124.485 1.00 60.71 ? 405 ALA B CB  1 
ATOM   6309  N N   . TYR B 1 406 ? 94.856  87.184  127.406 1.00 64.66 ? 406 TYR B N   1 
ATOM   6310  C CA  . TYR B 1 406 ? 94.437  87.723  128.688 1.00 64.66 ? 406 TYR B CA  1 
ATOM   6311  C C   . TYR B 1 406 ? 95.476  87.454  129.762 1.00 64.66 ? 406 TYR B C   1 
ATOM   6312  O O   . TYR B 1 406 ? 96.207  86.465  129.698 1.00 64.66 ? 406 TYR B O   1 
ATOM   6313  C CB  . TYR B 1 406 ? 93.107  87.111  129.097 1.00 64.66 ? 406 TYR B CB  1 
ATOM   6314  C CG  . TYR B 1 406 ? 92.101  87.194  127.996 1.00 64.66 ? 406 TYR B CG  1 
ATOM   6315  C CD1 . TYR B 1 406 ? 91.444  88.378  127.730 1.00 64.66 ? 406 TYR B CD1 1 
ATOM   6316  C CD2 . TYR B 1 406 ? 91.835  86.103  127.191 1.00 64.66 ? 406 TYR B CD2 1 
ATOM   6317  C CE1 . TYR B 1 406 ? 90.525  88.468  126.712 1.00 64.66 ? 406 TYR B CE1 1 
ATOM   6318  C CE2 . TYR B 1 406 ? 90.920  86.184  126.170 1.00 64.66 ? 406 TYR B CE2 1 
ATOM   6319  C CZ  . TYR B 1 406 ? 90.267  87.371  125.935 1.00 64.66 ? 406 TYR B CZ  1 
ATOM   6320  O OH  . TYR B 1 406 ? 89.353  87.472  124.918 1.00 64.66 ? 406 TYR B OH  1 
ATOM   6321  N N   . VAL B 1 407 ? 95.546  88.354  130.745 1.00 59.61 ? 407 VAL B N   1 
ATOM   6322  C CA  . VAL B 1 407 ? 96.392  88.174  131.914 1.00 59.61 ? 407 VAL B CA  1 
ATOM   6323  C C   . VAL B 1 407 ? 95.595  88.216  133.213 1.00 59.61 ? 407 VAL B C   1 
ATOM   6324  O O   . VAL B 1 407 ? 95.833  87.402  134.105 1.00 59.61 ? 407 VAL B O   1 
ATOM   6325  C CB  . VAL B 1 407 ? 97.553  89.189  131.941 1.00 59.61 ? 407 VAL B CB  1 
ATOM   6326  C CG1 . VAL B 1 407 ? 98.363  89.087  130.668 1.00 59.61 ? 407 VAL B CG1 1 
ATOM   6327  C CG2 . VAL B 1 407 ? 97.041  90.583  132.082 1.00 59.61 ? 407 VAL B CG2 1 
ATOM   6328  N N   . TRP B 1 408 ? 94.636  89.132  133.343 1.00 56.22 ? 408 TRP B N   1 
ATOM   6329  C CA  . TRP B 1 408 ? 93.871  89.254  134.576 1.00 56.22 ? 408 TRP B CA  1 
ATOM   6330  C C   . TRP B 1 408 ? 92.401  89.483  134.275 1.00 56.22 ? 408 TRP B C   1 
ATOM   6331  O O   . TRP B 1 408 ? 92.051  90.228  133.355 1.00 56.22 ? 408 TRP B O   1 
ATOM   6332  C CB  . TRP B 1 408 ? 94.391  90.400  135.457 1.00 56.22 ? 408 TRP B CB  1 
ATOM   6333  C CG  . TRP B 1 408 ? 95.820  90.290  135.768 1.00 56.22 ? 408 TRP B CG  1 
ATOM   6334  C CD1 . TRP B 1 408 ? 96.443  89.221  136.293 1.00 56.22 ? 408 TRP B CD1 1 
ATOM   6335  C CD2 . TRP B 1 408 ? 96.824  91.280  135.562 1.00 56.22 ? 408 TRP B CD2 1 
ATOM   6336  N NE1 . TRP B 1 408 ? 97.779  89.467  136.431 1.00 56.22 ? 408 TRP B NE1 1 
ATOM   6337  C CE2 . TRP B 1 408 ? 98.039  90.731  135.985 1.00 56.22 ? 408 TRP B CE2 1 
ATOM   6338  C CE3 . TRP B 1 408 ? 96.815  92.577  135.064 1.00 56.22 ? 408 TRP B CE3 1 
ATOM   6339  C CZ2 . TRP B 1 408 ? 99.234  91.430  135.926 1.00 56.22 ? 408 TRP B CZ2 1 
ATOM   6340  C CZ3 . TRP B 1 408 ? 98.002  93.268  135.004 1.00 56.22 ? 408 TRP B CZ3 1 
ATOM   6341  C CH2 . TRP B 1 408 ? 99.195  92.696  135.432 1.00 56.22 ? 408 TRP B CH2 1 
ATOM   6342  N N   . ILE B 1 409 ? 91.547  88.849  135.072 1.00 62.47 ? 409 ILE B N   1 
ATOM   6343  C CA  . ILE B 1 409 ? 90.107  89.081  135.039 1.00 62.47 ? 409 ILE B CA  1 
ATOM   6344  C C   . ILE B 1 409 ? 89.735  89.694  136.377 1.00 62.47 ? 409 ILE B C   1 
ATOM   6345  O O   . ILE B 1 409 ? 89.824  89.029  137.420 1.00 62.47 ? 409 ILE B O   1 
ATOM   6346  C CB  . ILE B 1 409 ? 89.309  87.795  134.783 1.00 62.47 ? 409 ILE B CB  1 
ATOM   6347  C CG1 . ILE B 1 409 ? 89.990  86.950  133.714 1.00 62.47 ? 409 ILE B CG1 1 
ATOM   6348  C CG2 . ILE B 1 409 ? 87.894  88.120  134.362 1.00 62.47 ? 409 ILE B CG2 1 
ATOM   6349  C CD1 . ILE B 1 409 ? 90.068  87.631  132.377 1.00 62.47 ? 409 ILE B CD1 1 
ATOM   6350  N N   . SER B 1 410 ? 89.325  90.956  136.362 1.00 65.82 ? 410 SER B N   1 
ATOM   6351  C CA  . SER B 1 410 ? 89.136  91.703  137.591 1.00 65.82 ? 410 SER B CA  1 
ATOM   6352  C C   . SER B 1 410 ? 87.668  92.011  137.824 1.00 65.82 ? 410 SER B C   1 
ATOM   6353  O O   . SER B 1 410 ? 86.963  92.461  136.914 1.00 65.82 ? 410 SER B O   1 
ATOM   6354  C CB  . SER B 1 410 ? 89.934  92.994  137.550 1.00 65.82 ? 410 SER B CB  1 
ATOM   6355  O OG  . SER B 1 410 ? 89.536  93.850  138.592 1.00 65.82 ? 410 SER B OG  1 
ATOM   6356  N N   . LEU B 1 411 ? 87.230  91.786  139.058 1.00 69.42 ? 411 LEU B N   1 
ATOM   6357  C CA  . LEU B 1 411 ? 85.875  92.055  139.502 1.00 69.42 ? 411 LEU B CA  1 
ATOM   6358  C C   . LEU B 1 411 ? 85.890  93.061  140.640 1.00 69.42 ? 411 LEU B C   1 
ATOM   6359  O O   . LEU B 1 411 ? 86.847  93.138  141.411 1.00 69.42 ? 411 LEU B O   1 
ATOM   6360  C CB  . LEU B 1 411 ? 85.187  90.786  139.987 1.00 69.42 ? 411 LEU B CB  1 
ATOM   6361  C CG  . LEU B 1 411 ? 84.958  89.688  138.966 1.00 69.42 ? 411 LEU B CG  1 
ATOM   6362  C CD1 . LEU B 1 411 ? 86.172  88.792  138.873 1.00 69.42 ? 411 LEU B CD1 1 
ATOM   6363  C CD2 . LEU B 1 411 ? 83.736  88.919  139.374 1.00 69.42 ? 411 LEU B CD2 1 
ATOM   6364  N N   . ALA B 1 412 ? 84.817  93.839  140.726 1.00 73.59 ? 412 ALA B N   1 
ATOM   6365  C CA  . ALA B 1 412 ? 84.533  94.660  141.892 1.00 73.59 ? 412 ALA B CA  1 
ATOM   6366  C C   . ALA B 1 412 ? 83.113  95.174  141.778 1.00 73.59 ? 412 ALA B C   1 
ATOM   6367  O O   . ALA B 1 412 ? 82.744  95.744  140.750 1.00 73.59 ? 412 ALA B O   1 
ATOM   6368  C CB  . ALA B 1 412 ? 85.508  95.827  142.014 1.00 73.59 ? 412 ALA B CB  1 
ATOM   6369  N N   . TYR B 1 413 ? 82.304  94.984  142.806 1.00 85.15 ? 413 TYR B N   1 
ATOM   6370  C CA  . TYR B 1 413 ? 80.957  95.513  142.738 1.00 85.15 ? 413 TYR B CA  1 
ATOM   6371  C C   . TYR B 1 413 ? 80.895  96.872  143.416 1.00 85.15 ? 413 TYR B C   1 
ATOM   6372  O O   . TYR B 1 413 ? 81.464  97.092  144.486 1.00 85.15 ? 413 TYR B O   1 
ATOM   6373  C CB  . TYR B 1 413 ? 79.956  94.556  143.373 1.00 85.15 ? 413 TYR B CB  1 
ATOM   6374  C CG  . TYR B 1 413 ? 78.531  94.874  143.003 1.00 85.15 ? 413 TYR B CG  1 
ATOM   6375  C CD1 . TYR B 1 413 ? 78.062  94.644  141.719 1.00 85.15 ? 413 TYR B CD1 1 
ATOM   6376  C CD2 . TYR B 1 413 ? 77.658  95.417  143.930 1.00 85.15 ? 413 TYR B CD2 1 
ATOM   6377  C CE1 . TYR B 1 413 ? 76.761  94.936  141.368 1.00 85.15 ? 413 TYR B CE1 1 
ATOM   6378  C CE2 . TYR B 1 413 ? 76.353  95.714  143.589 1.00 85.15 ? 413 TYR B CE2 1 
ATOM   6379  C CZ  . TYR B 1 413 ? 75.911  95.473  142.306 1.00 85.15 ? 413 TYR B CZ  1 
ATOM   6380  O OH  . TYR B 1 413 ? 74.613  95.769  141.965 1.00 85.15 ? 413 TYR B OH  1 
ATOM   6381  N N   . LYS B 1 414 ? 80.194  97.796  142.775 1.00 82.71 ? 414 LYS B N   1 
ATOM   6382  C CA  . LYS B 1 414 ? 80.031  99.135  143.314 1.00 82.71 ? 414 LYS B CA  1 
ATOM   6383  C C   . LYS B 1 414 ? 78.538  99.388  143.444 1.00 82.71 ? 414 LYS B C   1 
ATOM   6384  O O   . LYS B 1 414 ? 77.732  98.464  143.301 1.00 82.71 ? 414 LYS B O   1 
ATOM   6385  C CB  . LYS B 1 414 ? 80.781  100.158 142.445 1.00 82.71 ? 414 LYS B CB  1 
ATOM   6386  C CG  . LYS B 1 414 ? 82.268  100.147 142.726 1.00 82.71 ? 414 LYS B CG  1 
ATOM   6387  C CD  . LYS B 1 414 ? 83.059  101.049 141.813 1.00 82.71 ? 414 LYS B CD  1 
ATOM   6388  C CE  . LYS B 1 414 ? 84.534  100.989 142.179 1.00 82.71 ? 414 LYS B CE  1 
ATOM   6389  N NZ  . LYS B 1 414 ? 85.399  101.699 141.203 1.00 82.71 ? 414 LYS B NZ  1 
ATOM   6390  N N   . LYS B 1 415 ? 78.163  100.636 143.713 1.00 91.14 ? 415 LYS B N   1 
ATOM   6391  C CA  . LYS B 1 415 ? 76.813  100.911 144.194 1.00 91.14 ? 415 LYS B CA  1 
ATOM   6392  C C   . LYS B 1 415 ? 75.759  100.586 143.138 1.00 91.14 ? 415 LYS B C   1 
ATOM   6393  O O   . LYS B 1 415 ? 74.584  100.382 143.463 1.00 91.14 ? 415 LYS B O   1 
ATOM   6394  C CB  . LYS B 1 415 ? 76.714  102.369 144.644 1.00 91.14 ? 415 LYS B CB  1 
ATOM   6395  C CG  . LYS B 1 415 ? 75.410  102.741 145.339 1.00 91.14 ? 415 LYS B CG  1 
ATOM   6396  C CD  . LYS B 1 415 ? 74.416  103.365 144.380 1.00 91.14 ? 415 LYS B CD  1 
ATOM   6397  C CE  . LYS B 1 415 ? 74.867  104.741 143.940 1.00 91.14 ? 415 LYS B CE  1 
ATOM   6398  N NZ  . LYS B 1 415 ? 73.896  105.358 142.993 1.00 91.14 ? 415 LYS B NZ  1 
ATOM   6399  N N   . THR B 1 416 ? 76.157  100.510 141.866 1.00 88.05 ? 416 THR B N   1 
ATOM   6400  C CA  . THR B 1 416 ? 75.183  100.274 140.809 1.00 88.05 ? 416 THR B CA  1 
ATOM   6401  C C   . THR B 1 416 ? 75.649  99.251  139.776 1.00 88.05 ? 416 THR B C   1 
ATOM   6402  O O   . THR B 1 416 ? 74.935  99.010  138.798 1.00 88.05 ? 416 THR B O   1 
ATOM   6403  C CB  . THR B 1 416 ? 74.828  101.598 140.123 1.00 88.05 ? 416 THR B CB  1 
ATOM   6404  O OG1 . THR B 1 416 ? 74.787  102.635 141.108 1.00 88.05 ? 416 THR B OG1 1 
ATOM   6405  C CG2 . THR B 1 416 ? 73.454  101.518 139.477 1.00 88.05 ? 416 THR B CG2 1 
ATOM   6406  N N   . GLY B 1 417 ? 76.808  98.630  139.962 1.00 82.27 ? 417 GLY B N   1 
ATOM   6407  C CA  . GLY B 1 417 ? 77.245  97.615  139.037 1.00 82.27 ? 417 GLY B CA  1 
ATOM   6408  C C   . GLY B 1 417 ? 78.632  97.079  139.316 1.00 82.27 ? 417 GLY B C   1 
ATOM   6409  O O   . GLY B 1 417 ? 79.421  97.668  140.060 1.00 82.27 ? 417 GLY B O   1 
ATOM   6410  N N   . PRO B 1 418 ? 78.952  95.936  138.719 1.00 75.56 ? 418 PRO B N   1 
ATOM   6411  C CA  . PRO B 1 418 ? 80.287  95.362  138.870 1.00 75.56 ? 418 PRO B CA  1 
ATOM   6412  C C   . PRO B 1 418 ? 81.315  96.152  138.079 1.00 75.56 ? 418 PRO B C   1 
ATOM   6413  O O   . PRO B 1 418 ? 81.003  96.905  137.158 1.00 75.56 ? 418 PRO B O   1 
ATOM   6414  C CB  . PRO B 1 418 ? 80.138  93.947  138.304 1.00 75.56 ? 418 PRO B CB  1 
ATOM   6415  C CG  . PRO B 1 418 ? 78.679  93.700  138.254 1.00 75.56 ? 418 PRO B CG  1 
ATOM   6416  C CD  . PRO B 1 418 ? 78.055  95.026  137.998 1.00 75.56 ? 418 PRO B CD  1 
ATOM   6417  N N   . TYR B 1 419 ? 82.564  95.945  138.445 1.00 68.67 ? 419 TYR B N   1 
ATOM   6418  C CA  . TYR B 1 419 ? 83.688  96.598  137.788 1.00 68.67 ? 419 TYR B CA  1 
ATOM   6419  C C   . TYR B 1 419 ? 84.560  95.469  137.274 1.00 68.67 ? 419 TYR B C   1 
ATOM   6420  O O   . TYR B 1 419 ? 85.589  95.139  137.861 1.00 68.67 ? 419 TYR B O   1 
ATOM   6421  C CB  . TYR B 1 419 ? 84.408  97.485  138.771 1.00 68.67 ? 419 TYR B CB  1 
ATOM   6422  C CG  . TYR B 1 419 ? 85.379  98.470  138.197 1.00 68.67 ? 419 TYR B CG  1 
ATOM   6423  C CD1 . TYR B 1 419 ? 86.711  98.131  138.012 1.00 68.67 ? 419 TYR B CD1 1 
ATOM   6424  C CD2 . TYR B 1 419 ? 84.977  99.757  137.883 1.00 68.67 ? 419 TYR B CD2 1 
ATOM   6425  C CE1 . TYR B 1 419 ? 87.611  99.045  137.507 1.00 68.67 ? 419 TYR B CE1 1 
ATOM   6426  C CE2 . TYR B 1 419 ? 85.866  100.673 137.378 1.00 68.67 ? 419 TYR B CE2 1 
ATOM   6427  C CZ  . TYR B 1 419 ? 87.179  100.312 137.191 1.00 68.67 ? 419 TYR B CZ  1 
ATOM   6428  O OH  . TYR B 1 419 ? 88.063  101.228 136.688 1.00 68.67 ? 419 TYR B OH  1 
ATOM   6429  N N   . ILE B 1 420 ? 84.160  94.904  136.143 1.00 65.19 ? 420 ILE B N   1 
ATOM   6430  C CA  . ILE B 1 420 ? 84.850  93.777  135.538 1.00 65.19 ? 420 ILE B CA  1 
ATOM   6431  C C   . ILE B 1 420 ? 85.720  94.327  134.430 1.00 65.19 ? 420 ILE B C   1 
ATOM   6432  O O   . ILE B 1 420 ? 85.213  94.826  133.419 1.00 65.19 ? 420 ILE B O   1 
ATOM   6433  C CB  . ILE B 1 420 ? 83.867  92.734  134.991 1.00 65.19 ? 420 ILE B CB  1 
ATOM   6434  C CG1 . ILE B 1 420 ? 82.900  92.289  136.082 1.00 65.19 ? 420 ILE B CG1 1 
ATOM   6435  C CG2 . ILE B 1 420 ? 84.623  91.554  134.438 1.00 65.19 ? 420 ILE B CG2 1 
ATOM   6436  C CD1 . ILE B 1 420 ? 82.056  91.116  135.693 1.00 65.19 ? 420 ILE B CD1 1 
ATOM   6437  N N   . THR B 1 421 ? 87.022  94.258  134.620 1.00 59.05 ? 421 THR B N   1 
ATOM   6438  C CA  . THR B 1 421 ? 87.963  94.705  133.615 1.00 59.05 ? 421 THR B CA  1 
ATOM   6439  C C   . THR B 1 421 ? 88.809  93.536  133.152 1.00 59.05 ? 421 THR B C   1 
ATOM   6440  O O   . THR B 1 421 ? 89.285  92.733  133.963 1.00 59.05 ? 421 THR B O   1 
ATOM   6441  C CB  . THR B 1 421 ? 88.813  95.855  134.134 1.00 59.05 ? 421 THR B CB  1 
ATOM   6442  O OG1 . THR B 1 421 ? 89.974  96.021  133.313 1.00 59.05 ? 421 THR B OG1 1 
ATOM   6443  C CG2 . THR B 1 421 ? 89.169  95.657  135.553 1.00 59.05 ? 421 THR B CG2 1 
ATOM   6444  N N   . VAL B 1 422 ? 88.954  93.439  131.839 1.00 55.05 ? 422 VAL B N   1 
ATOM   6445  C CA  . VAL B 1 422 ? 89.599  92.314  131.185 1.00 55.05 ? 422 VAL B CA  1 
ATOM   6446  C C   . VAL B 1 422 ? 90.962  92.838  130.766 1.00 55.05 ? 422 VAL B C   1 
ATOM   6447  O O   . VAL B 1 422 ? 91.123  93.434  129.708 1.00 55.05 ? 422 VAL B O   1 
ATOM   6448  C CB  . VAL B 1 422 ? 88.780  91.806  130.001 1.00 55.05 ? 422 VAL B CB  1 
ATOM   6449  C CG1 . VAL B 1 422 ? 89.504  90.712  129.289 1.00 55.05 ? 422 VAL B CG1 1 
ATOM   6450  C CG2 . VAL B 1 422 ? 87.433  91.322  130.468 1.00 55.05 ? 422 VAL B CG2 1 
ATOM   6451  N N   . TYR B 1 423 ? 91.953  92.652  131.621 1.00 55.07 ? 423 TYR B N   1 
ATOM   6452  C CA  . TYR B 1 423 ? 93.268  93.141  131.266 1.00 55.07 ? 423 TYR B CA  1 
ATOM   6453  C C   . TYR B 1 423 ? 93.867  92.226  130.223 1.00 55.07 ? 423 TYR B C   1 
ATOM   6454  O O   . TYR B 1 423 ? 93.677  91.011  130.257 1.00 55.07 ? 423 TYR B O   1 
ATOM   6455  C CB  . TYR B 1 423 ? 94.159  93.221  132.493 1.00 55.07 ? 423 TYR B CB  1 
ATOM   6456  C CG  . TYR B 1 423 ? 93.560  94.052  133.592 1.00 55.07 ? 423 TYR B CG  1 
ATOM   6457  C CD1 . TYR B 1 423 ? 93.421  95.416  133.458 1.00 55.07 ? 423 TYR B CD1 1 
ATOM   6458  C CD2 . TYR B 1 423 ? 93.110  93.469  134.750 1.00 55.07 ? 423 TYR B CD2 1 
ATOM   6459  C CE1 . TYR B 1 423 ? 92.880  96.171  134.458 1.00 55.07 ? 423 TYR B CE1 1 
ATOM   6460  C CE2 . TYR B 1 423 ? 92.566  94.216  135.748 1.00 55.07 ? 423 TYR B CE2 1 
ATOM   6461  C CZ  . TYR B 1 423 ? 92.455  95.566  135.599 1.00 55.07 ? 423 TYR B CZ  1 
ATOM   6462  O OH  . TYR B 1 423 ? 91.908  96.318  136.609 1.00 55.07 ? 423 TYR B OH  1 
ATOM   6463  N N   . THR B 1 424 ? 94.563  92.818  129.270 1.00 50.75 ? 424 THR B N   1 
ATOM   6464  C CA  . THR B 1 424 ? 95.131  92.076  128.167 1.00 50.75 ? 424 THR B CA  1 
ATOM   6465  C C   . THR B 1 424 ? 96.621  92.314  128.129 1.00 50.75 ? 424 THR B C   1 
ATOM   6466  O O   . THR B 1 424 ? 97.167  93.119  128.879 1.00 50.75 ? 424 THR B O   1 
ATOM   6467  C CB  . THR B 1 424 ? 94.521  92.489  126.828 1.00 50.75 ? 424 THR B CB  1 
ATOM   6468  O OG1 . THR B 1 424 ? 94.758  93.883  126.615 1.00 50.75 ? 424 THR B OG1 1 
ATOM   6469  C CG2 . THR B 1 424 ? 93.033  92.230  126.809 1.00 50.75 ? 424 THR B CG2 1 
ATOM   6470  N N   . ASN B 1 425 ? 97.276  91.589  127.251 1.00 49.12 ? 425 ASN B N   1 
ATOM   6471  C CA  . ASN B 1 425 ? 98.639  91.921  126.887 1.00 49.12 ? 425 ASN B CA  1 
ATOM   6472  C C   . ASN B 1 425 ? 98.574  92.443  125.471 1.00 49.12 ? 425 ASN B C   1 
ATOM   6473  O O   . ASN B 1 425 ? 98.467  91.653  124.524 1.00 49.12 ? 425 ASN B O   1 
ATOM   6474  C CB  . ASN B 1 425 ? 99.555  90.704  126.977 1.00 49.12 ? 425 ASN B CB  1 
ATOM   6475  C CG  . ASN B 1 425 ? 101.004 91.079  126.939 1.00 49.12 ? 425 ASN B CG  1 
ATOM   6476  O OD1 . ASN B 1 425 ? 101.345 92.254  126.942 1.00 49.12 ? 425 ASN B OD1 1 
ATOM   6477  N ND2 . ASN B 1 425 ? 101.873 90.083  126.911 1.00 49.12 ? 425 ASN B ND2 1 
ATOM   6478  N N   . PRO B 1 426 ? 98.584  93.757  125.262 1.00 48.99 ? 426 PRO B N   1 
ATOM   6479  C CA  . PRO B 1 426 ? 98.641  94.272  123.896 1.00 48.99 ? 426 PRO B CA  1 
ATOM   6480  C C   . PRO B 1 426 ? 99.913  93.893  123.173 1.00 48.99 ? 426 PRO B C   1 
ATOM   6481  O O   . PRO B 1 426 ? 100.031 94.177  121.981 1.00 48.99 ? 426 PRO B O   1 
ATOM   6482  C CB  . PRO B 1 426 ? 98.534  95.785  124.093 1.00 48.99 ? 426 PRO B CB  1 
ATOM   6483  C CG  . PRO B 1 426 ? 98.995  96.015  125.473 1.00 48.99 ? 426 PRO B CG  1 
ATOM   6484  C CD  . PRO B 1 426 ? 98.550  94.836  126.253 1.00 48.99 ? 426 PRO B CD  1 
ATOM   6485  N N   . GLY B 1 427 ? 100.861 93.258  123.847 1.00 50.18 ? 427 GLY B N   1 
ATOM   6486  C CA  . GLY B 1 427 ? 102.076 92.811  123.207 1.00 50.18 ? 427 GLY B CA  1 
ATOM   6487  C C   . GLY B 1 427 ? 102.109 91.310  123.024 1.00 50.18 ? 427 GLY B C   1 
ATOM   6488  O O   . GLY B 1 427 ? 103.178 90.721  122.856 1.00 50.18 ? 427 GLY B O   1 
ATOM   6489  N N   . ALA B 1 428 ? 100.934 90.680  123.060 1.00 52.73 ? 428 ALA B N   1 
ATOM   6490  C CA  . ALA B 1 428 ? 100.862 89.246  122.823 1.00 52.73 ? 428 ALA B CA  1 
ATOM   6491  C C   . ALA B 1 428 ? 101.433 88.885  121.465 1.00 52.73 ? 428 ALA B C   1 
ATOM   6492  O O   . ALA B 1 428 ? 101.988 87.797  121.293 1.00 52.73 ? 428 ALA B O   1 
ATOM   6493  C CB  . ALA B 1 428 ? 99.421  88.767  122.927 1.00 52.73 ? 428 ALA B CB  1 
ATOM   6494  N N   . SER B 1 429 ? 101.312 89.791  120.497 1.00 51.94 ? 429 SER B N   1 
ATOM   6495  C CA  . SER B 1 429 ? 101.859 89.543  119.175 1.00 51.94 ? 429 SER B CA  1 
ATOM   6496  C C   . SER B 1 429 ? 103.351 89.271  119.239 1.00 51.94 ? 429 SER B C   1 
ATOM   6497  O O   . SER B 1 429 ? 103.892 88.582  118.372 1.00 51.94 ? 429 SER B O   1 
ATOM   6498  C CB  . SER B 1 429 ? 101.579 90.739  118.276 1.00 51.94 ? 429 SER B CB  1 
ATOM   6499  O OG  . SER B 1 429 ? 100.190 90.999  118.228 1.00 51.94 ? 429 SER B OG  1 
ATOM   6500  N N   . ILE B 1 430 ? 104.034 89.810  120.247 1.00 50.69 ? 430 ILE B N   1 
ATOM   6501  C CA  . ILE B 1 430 ? 105.455 89.545  120.389 1.00 50.69 ? 430 ILE B CA  1 
ATOM   6502  C C   . ILE B 1 430 ? 105.697 88.151  120.939 1.00 50.69 ? 430 ILE B C   1 
ATOM   6503  O O   . ILE B 1 430 ? 106.780 87.589  120.751 1.00 50.69 ? 430 ILE B O   1 
ATOM   6504  C CB  . ILE B 1 430 ? 106.099 90.612  121.285 1.00 50.69 ? 430 ILE B CB  1 
ATOM   6505  C CG1 . ILE B 1 430 ? 105.498 91.977  120.974 1.00 50.69 ? 430 ILE B CG1 1 
ATOM   6506  C CG2 . ILE B 1 430 ? 107.585 90.652  121.068 1.00 50.69 ? 430 ILE B CG2 1 
ATOM   6507  C CD1 . ILE B 1 430 ? 105.634 92.972  122.090 1.00 50.69 ? 430 ILE B CD1 1 
ATOM   6508  N N   . LEU B 1 431 ? 104.710 87.579  121.624 1.00 53.44 ? 431 LEU B N   1 
ATOM   6509  C CA  . LEU B 1 431 ? 104.837 86.232  122.157 1.00 53.44 ? 431 LEU B CA  1 
ATOM   6510  C C   . LEU B 1 431 ? 104.483 85.167  121.134 1.00 53.44 ? 431 LEU B C   1 
ATOM   6511  O O   . LEU B 1 431 ? 104.440 83.986  121.483 1.00 53.44 ? 431 LEU B O   1 
ATOM   6512  C CB  . LEU B 1 431 ? 103.958 86.073  123.395 1.00 53.44 ? 431 LEU B CB  1 
ATOM   6513  C CG  . LEU B 1 431 ? 104.188 87.121  124.481 1.00 53.44 ? 431 LEU B CG  1 
ATOM   6514  C CD1 . LEU B 1 431 ? 103.375 86.803  125.710 1.00 53.44 ? 431 LEU B CD1 1 
ATOM   6515  C CD2 . LEU B 1 431 ? 105.656 87.199  124.823 1.00 53.44 ? 431 LEU B CD2 1 
ATOM   6516  N N   . GLU B 1 432 ? 104.216 85.556  119.895 1.00 56.59 ? 432 GLU B N   1 
ATOM   6517  C CA  . GLU B 1 432 ? 103.915 84.606  118.840 1.00 56.59 ? 432 GLU B CA  1 
ATOM   6518  C C   . GLU B 1 432 ? 104.839 84.800  117.647 1.00 56.59 ? 432 GLU B C   1 
ATOM   6519  O O   . GLU B 1 432 ? 106.059 84.826  117.794 1.00 56.59 ? 432 GLU B O   1 
ATOM   6520  C CB  . GLU B 1 432 ? 102.461 84.744  118.409 1.00 56.59 ? 432 GLU B CB  1 
ATOM   6521  C CG  . GLU B 1 432 ? 101.485 84.584  119.542 1.00 56.59 ? 432 GLU B CG  1 
ATOM   6522  C CD  . GLU B 1 432 ? 101.394 83.154  120.025 1.00 56.59 ? 432 GLU B CD  1 
ATOM   6523  O OE1 . GLU B 1 432 ? 101.901 82.255  119.326 1.00 56.59 ? 432 GLU B OE1 1 
ATOM   6524  O OE2 . GLU B 1 432 ? 100.813 82.924  121.105 1.00 56.59 ? 432 GLU B OE2 1 
ATOM   6525  N N   . SER C 1 23  ? 90.602  123.387 125.616 1.00 57.67 ? 23  SER C N   1 
ATOM   6526  C CA  . SER C 1 23  ? 90.614  122.575 124.407 1.00 57.67 ? 23  SER C CA  1 
ATOM   6527  C C   . SER C 1 23  ? 91.379  123.281 123.303 1.00 57.67 ? 23  SER C C   1 
ATOM   6528  O O   . SER C 1 23  ? 90.939  124.311 122.800 1.00 57.67 ? 23  SER C O   1 
ATOM   6529  C CB  . SER C 1 23  ? 89.191  122.272 123.944 1.00 57.67 ? 23  SER C CB  1 
ATOM   6530  O OG  . SER C 1 23  ? 88.551  123.446 123.477 1.00 57.67 ? 23  SER C OG  1 
ATOM   6531  N N   . PRO C 1 24  ? 92.526  122.733 122.924 1.00 51.01 ? 24  PRO C N   1 
ATOM   6532  C CA  . PRO C 1 24  ? 93.325  123.367 121.877 1.00 51.01 ? 24  PRO C CA  1 
ATOM   6533  C C   . PRO C 1 24  ? 92.668  123.202 120.520 1.00 51.01 ? 24  PRO C C   1 
ATOM   6534  O O   . PRO C 1 24  ? 91.629  122.559 120.369 1.00 51.01 ? 24  PRO C O   1 
ATOM   6535  C CB  . PRO C 1 24  ? 94.657  122.618 121.946 1.00 51.01 ? 24  PRO C CB  1 
ATOM   6536  C CG  . PRO C 1 24  ? 94.293  121.282 122.460 1.00 51.01 ? 24  PRO C CG  1 
ATOM   6537  C CD  . PRO C 1 24  ? 93.136  121.482 123.401 1.00 51.01 ? 24  PRO C CD  1 
ATOM   6538  N N   . SER C 1 25  ? 93.286  123.807 119.536 1.00 45.25 ? 25  SER C N   1 
ATOM   6539  C CA  . SER C 1 25  ? 92.905  123.617 118.151 1.00 45.25 ? 25  SER C CA  1 
ATOM   6540  C C   . SER C 1 25  ? 93.905  122.697 117.477 1.00 45.25 ? 25  SER C C   1 
ATOM   6541  O O   . SER C 1 25  ? 95.051  122.583 117.917 1.00 45.25 ? 25  SER C O   1 
ATOM   6542  C CB  . SER C 1 25  ? 92.863  124.956 117.432 1.00 45.25 ? 25  SER C CB  1 
ATOM   6543  O OG  . SER C 1 25  ? 94.101  125.621 117.566 1.00 45.25 ? 25  SER C OG  1 
ATOM   6544  N N   . PRO C 1 26  ? 93.497  122.016 116.413 1.00 42.25 ? 26  PRO C N   1 
ATOM   6545  C CA  . PRO C 1 26  ? 94.400  121.077 115.746 1.00 42.25 ? 26  PRO C CA  1 
ATOM   6546  C C   . PRO C 1 26  ? 95.775  121.637 115.462 1.00 42.25 ? 26  PRO C C   1 
ATOM   6547  O O   . PRO C 1 26  ? 96.762  120.941 115.674 1.00 42.25 ? 26  PRO C O   1 
ATOM   6548  C CB  . PRO C 1 26  ? 93.652  120.752 114.457 1.00 42.25 ? 26  PRO C CB  1 
ATOM   6549  C CG  . PRO C 1 26  ? 92.248  120.834 114.850 1.00 42.25 ? 26  PRO C CG  1 
ATOM   6550  C CD  . PRO C 1 26  ? 92.146  121.960 115.838 1.00 42.25 ? 26  PRO C CD  1 
ATOM   6551  N N   . TRP C 1 27  ? 95.884  122.884 115.016 1.00 41.96 ? 27  TRP C N   1 
ATOM   6552  C CA  . TRP C 1 27  ? 97.219  123.398 114.745 1.00 41.96 ? 27  TRP C CA  1 
ATOM   6553  C C   . TRP C 1 27  ? 97.979  123.658 116.036 1.00 41.96 ? 27  TRP C C   1 
ATOM   6554  O O   . TRP C 1 27  ? 99.179  123.394 116.110 1.00 41.96 ? 27  TRP C O   1 
ATOM   6555  C CB  . TRP C 1 27  ? 97.161  124.651 113.869 1.00 41.96 ? 27  TRP C CB  1 
ATOM   6556  C CG  . TRP C 1 27  ? 96.222  125.696 114.288 1.00 41.96 ? 27  TRP C CG  1 
ATOM   6557  C CD1 . TRP C 1 27  ? 96.522  126.838 114.949 1.00 41.96 ? 27  TRP C CD1 1 
ATOM   6558  C CD2 . TRP C 1 27  ? 94.826  125.731 114.036 1.00 41.96 ? 27  TRP C CD2 1 
ATOM   6559  N NE1 . TRP C 1 27  ? 95.393  127.578 115.148 1.00 41.96 ? 27  TRP C NE1 1 
ATOM   6560  C CE2 . TRP C 1 27  ? 94.335  126.918 114.591 1.00 41.96 ? 27  TRP C CE2 1 
ATOM   6561  C CE3 . TRP C 1 27  ? 93.938  124.868 113.400 1.00 41.96 ? 27  TRP C CE3 1 
ATOM   6562  C CZ2 . TRP C 1 27  ? 93.002  127.264 114.535 1.00 41.96 ? 27  TRP C CZ2 1 
ATOM   6563  C CZ3 . TRP C 1 27  ? 92.615  125.210 113.347 1.00 41.96 ? 27  TRP C CZ3 1 
ATOM   6564  C CH2 . TRP C 1 27  ? 92.156  126.396 113.910 1.00 41.96 ? 27  TRP C CH2 1 
ATOM   6565  N N   . ASP C 1 28  ? 97.296  124.132 117.076 1.00 46.38 ? 28  ASP C N   1 
ATOM   6566  C CA  . ASP C 1 28  ? 97.958  124.348 118.356 1.00 46.38 ? 28  ASP C CA  1 
ATOM   6567  C C   . ASP C 1 28  ? 98.468  123.037 118.932 1.00 46.38 ? 28  ASP C C   1 
ATOM   6568  O O   . ASP C 1 28  ? 99.663  122.883 119.217 1.00 46.38 ? 28  ASP C O   1 
ATOM   6569  C CB  . ASP C 1 28  ? 96.990  125.007 119.328 1.00 46.38 ? 28  ASP C CB  1 
ATOM   6570  C CG  . ASP C 1 28  ? 96.587  126.381 118.890 1.00 46.38 ? 28  ASP C CG  1 
ATOM   6571  O OD1 . ASP C 1 28  ? 97.476  127.154 118.486 1.00 46.38 ? 28  ASP C OD1 1 
ATOM   6572  O OD2 . ASP C 1 28  ? 95.380  126.691 118.949 1.00 46.38 ? 28  ASP C OD2 1 
ATOM   6573  N N   . PHE C 1 29  ? 97.558  122.083 119.122 1.00 44.17 ? 29  PHE C N   1 
ATOM   6574  C CA  . PHE C 1 29  ? 97.930  120.772 119.633 1.00 44.17 ? 29  PHE C CA  1 
ATOM   6575  C C   . PHE C 1 29  ? 99.027  120.144 118.793 1.00 44.17 ? 29  PHE C C   1 
ATOM   6576  O O   . PHE C 1 29  ? 99.998  119.601 119.328 1.00 44.17 ? 29  PHE C O   1 
ATOM   6577  C CB  . PHE C 1 29  ? 96.696  119.874 119.661 1.00 44.17 ? 29  PHE C CB  1 
ATOM   6578  C CG  . PHE C 1 29  ? 96.869  118.625 120.464 1.00 44.17 ? 29  PHE C CG  1 
ATOM   6579  C CD1 . PHE C 1 29  ? 97.627  118.625 121.617 1.00 44.17 ? 29  PHE C CD1 1 
ATOM   6580  C CD2 . PHE C 1 29  ? 96.257  117.453 120.076 1.00 44.17 ? 29  PHE C CD2 1 
ATOM   6581  C CE1 . PHE C 1 29  ? 97.778  117.479 122.355 1.00 44.17 ? 29  PHE C CE1 1 
ATOM   6582  C CE2 . PHE C 1 29  ? 96.407  116.306 120.812 1.00 44.17 ? 29  PHE C CE2 1 
ATOM   6583  C CZ  . PHE C 1 29  ? 97.168  116.320 121.952 1.00 44.17 ? 29  PHE C CZ  1 
ATOM   6584  N N   . LEU C 1 30  ? 98.900  120.225 117.474 1.00 39.93 ? 30  LEU C N   1 
ATOM   6585  C CA  . LEU C 1 30  ? 99.855  119.565 116.603 1.00 39.93 ? 30  LEU C CA  1 
ATOM   6586  C C   . LEU C 1 30  ? 101.219 120.224 116.682 1.00 39.93 ? 30  LEU C C   1 
ATOM   6587  O O   . LEU C 1 30  ? 102.236 119.534 116.746 1.00 39.93 ? 30  LEU C O   1 
ATOM   6588  C CB  . LEU C 1 30  ? 99.321  119.555 115.178 1.00 39.93 ? 30  LEU C CB  1 
ATOM   6589  C CG  . LEU C 1 30  ? 98.276  118.467 114.945 1.00 39.93 ? 30  LEU C CG  1 
ATOM   6590  C CD1 . LEU C 1 30  ? 97.644  118.600 113.576 1.00 39.93 ? 30  LEU C CD1 1 
ATOM   6591  C CD2 . LEU C 1 30  ? 98.897  117.106 115.124 1.00 39.93 ? 30  LEU C CD2 1 
ATOM   6592  N N   . GLY C 1 31  ? 101.272 121.552 116.696 1.00 43.07 ? 31  GLY C N   1 
ATOM   6593  C CA  . GLY C 1 31  ? 102.540 122.215 116.919 1.00 43.07 ? 31  GLY C CA  1 
ATOM   6594  C C   . GLY C 1 31  ? 103.132 121.860 118.261 1.00 43.07 ? 31  GLY C C   1 
ATOM   6595  O O   . GLY C 1 31  ? 104.352 121.887 118.436 1.00 43.07 ? 31  GLY C O   1 
ATOM   6596  N N   . ARG C 1 32  ? 102.279 121.504 119.222 1.00 44.15 ? 32  ARG C N   1 
ATOM   6597  C CA  . ARG C 1 32  ? 102.782 121.066 120.516 1.00 44.15 ? 32  ARG C CA  1 
ATOM   6598  C C   . ARG C 1 32  ? 103.392 119.672 120.438 1.00 44.15 ? 32  ARG C C   1 
ATOM   6599  O O   . ARG C 1 32  ? 104.463 119.430 121.004 1.00 44.15 ? 32  ARG C O   1 
ATOM   6600  C CB  . ARG C 1 32  ? 101.661 121.108 121.546 1.00 44.15 ? 32  ARG C CB  1 
ATOM   6601  C CG  . ARG C 1 32  ? 101.223 122.506 121.888 1.00 44.15 ? 32  ARG C CG  1 
ATOM   6602  C CD  . ARG C 1 32  ? 100.907 122.625 123.341 1.00 44.15 ? 32  ARG C CD  1 
ATOM   6603  N NE  . ARG C 1 32  ? 99.595  122.078 123.628 1.00 44.15 ? 32  ARG C NE  1 
ATOM   6604  C CZ  . ARG C 1 32  ? 98.494  122.810 123.688 1.00 44.15 ? 32  ARG C CZ  1 
ATOM   6605  N NH1 . ARG C 1 32  ? 98.562  124.113 123.478 1.00 44.15 ? 32  ARG C NH1 1 
ATOM   6606  N NH2 . ARG C 1 32  ? 97.329  122.241 123.957 1.00 44.15 ? 32  ARG C NH2 1 
ATOM   6607  N N   . VAL C 1 33  ? 102.741 118.744 119.737 1.00 40.83 ? 33  VAL C N   1 
ATOM   6608  C CA  . VAL C 1 33  ? 103.153 117.346 119.807 1.00 40.83 ? 33  VAL C CA  1 
ATOM   6609  C C   . VAL C 1 33  ? 104.057 116.939 118.649 1.00 40.83 ? 33  VAL C C   1 
ATOM   6610  O O   . VAL C 1 33  ? 104.901 116.053 118.807 1.00 40.83 ? 33  VAL C O   1 
ATOM   6611  C CB  . VAL C 1 33  ? 101.935 116.408 119.891 1.00 40.83 ? 33  VAL C CB  1 
ATOM   6612  C CG1 . VAL C 1 33  ? 100.995 116.860 120.970 1.00 40.83 ? 33  VAL C CG1 1 
ATOM   6613  C CG2 . VAL C 1 33  ? 101.225 116.331 118.579 1.00 40.83 ? 33  VAL C CG2 1 
ATOM   6614  N N   . LEU C 1 34  ? 103.914 117.573 117.490 1.00 37.75 ? 34  LEU C N   1 
ATOM   6615  C CA  . LEU C 1 34  ? 104.611 117.087 116.309 1.00 37.75 ? 34  LEU C CA  1 
ATOM   6616  C C   . LEU C 1 34  ? 106.102 117.365 116.395 1.00 37.75 ? 34  LEU C C   1 
ATOM   6617  O O   . LEU C 1 34  ? 106.538 118.385 116.926 1.00 37.75 ? 34  LEU C O   1 
ATOM   6618  C CB  . LEU C 1 34  ? 104.056 117.727 115.039 1.00 37.75 ? 34  LEU C CB  1 
ATOM   6619  C CG  . LEU C 1 34  ? 102.676 117.291 114.561 1.00 37.75 ? 34  LEU C CG  1 
ATOM   6620  C CD1 . LEU C 1 34  ? 102.242 118.117 113.377 1.00 37.75 ? 34  LEU C CD1 1 
ATOM   6621  C CD2 . LEU C 1 34  ? 102.672 115.829 114.222 1.00 37.75 ? 34  LEU C CD2 1 
ATOM   6622  N N   . GLN C 1 35  ? 106.883 116.436 115.866 1.00 41.40 ? 35  GLN C N   1 
ATOM   6623  C CA  . GLN C 1 35  ? 108.306 116.632 115.665 1.00 41.40 ? 35  GLN C CA  1 
ATOM   6624  C C   . GLN C 1 35  ? 108.516 117.109 114.241 1.00 41.40 ? 35  GLN C C   1 
ATOM   6625  O O   . GLN C 1 35  ? 107.975 116.521 113.303 1.00 41.40 ? 35  GLN C O   1 
ATOM   6626  C CB  . GLN C 1 35  ? 109.087 115.341 115.905 1.00 41.40 ? 35  GLN C CB  1 
ATOM   6627  C CG  . GLN C 1 35  ? 108.671 114.571 117.133 1.00 41.40 ? 35  GLN C CG  1 
ATOM   6628  C CD  . GLN C 1 35  ? 109.159 115.213 118.398 1.00 41.40 ? 35  GLN C CD  1 
ATOM   6629  O OE1 . GLN C 1 35  ? 108.385 115.472 119.316 1.00 41.40 ? 35  GLN C OE1 1 
ATOM   6630  N NE2 . GLN C 1 35  ? 110.454 115.483 118.458 1.00 41.40 ? 35  GLN C NE2 1 
ATOM   6631  N N   . PHE C 1 36  ? 109.289 118.172 114.082 1.00 38.54 ? 36  PHE C N   1 
ATOM   6632  C CA  . PHE C 1 36  ? 109.536 118.772 112.783 1.00 38.54 ? 36  PHE C CA  1 
ATOM   6633  C C   . PHE C 1 36  ? 110.939 118.429 112.320 1.00 38.54 ? 36  PHE C C   1 
ATOM   6634  O O   . PHE C 1 36  ? 111.893 118.527 113.092 1.00 38.54 ? 36  PHE C O   1 
ATOM   6635  C CB  . PHE C 1 36  ? 109.355 120.283 112.847 1.00 38.54 ? 36  PHE C CB  1 
ATOM   6636  C CG  . PHE C 1 36  ? 107.941 120.703 113.049 1.00 38.54 ? 36  PHE C CG  1 
ATOM   6637  C CD1 . PHE C 1 36  ? 107.432 120.861 114.311 1.00 38.54 ? 36  PHE C CD1 1 
ATOM   6638  C CD2 . PHE C 1 36  ? 107.118 120.932 111.973 1.00 38.54 ? 36  PHE C CD2 1 
ATOM   6639  C CE1 . PHE C 1 36  ? 106.132 121.242 114.493 1.00 38.54 ? 36  PHE C CE1 1 
ATOM   6640  C CE2 . PHE C 1 36  ? 105.822 121.314 112.154 1.00 38.54 ? 36  PHE C CE2 1 
ATOM   6641  C CZ  . PHE C 1 36  ? 105.329 121.470 113.414 1.00 38.54 ? 36  PHE C CZ  1 
ATOM   6642  N N   . GLN C 1 37  ? 111.060 118.022 111.057 1.00 42.19 ? 37  GLN C N   1 
ATOM   6643  C CA  . GLN C 1 37  ? 112.371 117.659 110.537 1.00 42.19 ? 37  GLN C CA  1 
ATOM   6644  C C   . GLN C 1 37  ? 113.307 118.854 110.491 1.00 42.19 ? 37  GLN C C   1 
ATOM   6645  O O   . GLN C 1 37  ? 114.523 118.695 110.628 1.00 42.19 ? 37  GLN C O   1 
ATOM   6646  C CB  . GLN C 1 37  ? 112.248 117.068 109.140 1.00 42.19 ? 37  GLN C CB  1 
ATOM   6647  C CG  . GLN C 1 37  ? 111.165 116.055 108.964 1.00 42.19 ? 37  GLN C CG  1 
ATOM   6648  C CD  . GLN C 1 37  ? 111.196 115.454 107.579 1.00 42.19 ? 37  GLN C CD  1 
ATOM   6649  O OE1 . GLN C 1 37  ? 112.259 115.311 106.982 1.00 42.19 ? 37  GLN C OE1 1 
ATOM   6650  N NE2 . GLN C 1 37  ? 110.027 115.127 107.045 1.00 42.19 ? 37  GLN C NE2 1 
ATOM   6651  N N   . HIS C 1 38  ? 112.766 120.049 110.293 1.00 36.94 ? 38  HIS C N   1 
ATOM   6652  C CA  . HIS C 1 38  ? 113.574 121.237 110.107 1.00 36.94 ? 38  HIS C CA  1 
ATOM   6653  C C   . HIS C 1 38  ? 112.901 122.412 110.793 1.00 36.94 ? 38  HIS C C   1 
ATOM   6654  O O   . HIS C 1 38  ? 111.674 122.469 110.897 1.00 36.94 ? 38  HIS C O   1 
ATOM   6655  C CB  . HIS C 1 38  ? 113.776 121.525 108.623 1.00 36.94 ? 38  HIS C CB  1 
ATOM   6656  C CG  . HIS C 1 38  ? 114.854 122.517 108.339 1.00 36.94 ? 38  HIS C CG  1 
ATOM   6657  N ND1 . HIS C 1 38  ? 114.685 123.869 108.523 1.00 36.94 ? 38  HIS C ND1 1 
ATOM   6658  C CD2 . HIS C 1 38  ? 116.110 122.355 107.867 1.00 36.94 ? 38  HIS C CD2 1 
ATOM   6659  C CE1 . HIS C 1 38  ? 115.794 124.500 108.185 1.00 36.94 ? 38  HIS C CE1 1 
ATOM   6660  N NE2 . HIS C 1 38  ? 116.675 123.603 107.783 1.00 36.94 ? 38  HIS C NE2 1 
ATOM   6661  N N   . GLY C 1 39  ? 113.722 123.350 111.268 1.00 38.52 ? 39  GLY C N   1 
ATOM   6662  C CA  . GLY C 1 39  ? 113.183 124.512 111.950 1.00 38.52 ? 39  GLY C CA  1 
ATOM   6663  C C   . GLY C 1 39  ? 112.336 125.381 111.044 1.00 38.52 ? 39  GLY C C   1 
ATOM   6664  O O   . GLY C 1 39  ? 111.316 125.927 111.469 1.00 38.52 ? 39  GLY C O   1 
ATOM   6665  N N   . ASP C 1 40  ? 112.751 125.528 109.785 1.00 38.59 ? 40  ASP C N   1 
ATOM   6666  C CA  . ASP C 1 40  ? 111.965 126.303 108.835 1.00 38.59 ? 40  ASP C CA  1 
ATOM   6667  C C   . ASP C 1 40  ? 110.585 125.712 108.647 1.00 38.59 ? 40  ASP C C   1 
ATOM   6668  O O   . ASP C 1 40  ? 109.621 126.453 108.454 1.00 38.59 ? 40  ASP C O   1 
ATOM   6669  C CB  . ASP C 1 40  ? 112.682 126.391 107.492 1.00 38.59 ? 40  ASP C CB  1 
ATOM   6670  C CG  . ASP C 1 40  ? 113.570 127.609 107.386 1.00 38.59 ? 40  ASP C CG  1 
ATOM   6671  O OD1 . ASP C 1 40  ? 113.675 128.350 108.380 1.00 38.59 ? 40  ASP C OD1 1 
ATOM   6672  O OD2 . ASP C 1 40  ? 114.170 127.828 106.315 1.00 38.59 ? 40  ASP C OD2 1 
ATOM   6673  N N   . HIS C 1 41  ? 110.461 124.387 108.698 1.00 35.62 ? 41  HIS C N   1 
ATOM   6674  C CA  . HIS C 1 41  ? 109.132 123.797 108.668 1.00 35.62 ? 41  HIS C CA  1 
ATOM   6675  C C   . HIS C 1 41  ? 108.330 124.219 109.886 1.00 35.62 ? 41  HIS C C   1 
ATOM   6676  O O   . HIS C 1 41  ? 107.126 124.446 109.787 1.00 35.62 ? 41  HIS C O   1 
ATOM   6677  C CB  . HIS C 1 41  ? 109.208 122.272 108.594 1.00 35.62 ? 41  HIS C CB  1 
ATOM   6678  C CG  . HIS C 1 41  ? 110.145 121.746 107.552 1.00 35.62 ? 41  HIS C CG  1 
ATOM   6679  N ND1 . HIS C 1 41  ? 110.435 120.406 107.433 1.00 35.62 ? 41  HIS C ND1 1 
ATOM   6680  C CD2 . HIS C 1 41  ? 110.857 122.369 106.587 1.00 35.62 ? 41  HIS C CD2 1 
ATOM   6681  C CE1 . HIS C 1 41  ? 111.289 120.227 106.445 1.00 35.62 ? 41  HIS C CE1 1 
ATOM   6682  N NE2 . HIS C 1 41  ? 111.564 121.403 105.916 1.00 35.62 ? 41  HIS C NE2 1 
ATOM   6683  N N   . LYS C 1 42  ? 108.986 124.378 111.032 1.00 38.87 ? 42  LYS C N   1 
ATOM   6684  C CA  . LYS C 1 42  ? 108.281 124.823 112.228 1.00 38.87 ? 42  LYS C CA  1 
ATOM   6685  C C   . LYS C 1 42  ? 107.803 126.262 112.087 1.00 38.87 ? 42  LYS C C   1 
ATOM   6686  O O   . LYS C 1 42  ? 106.671 126.589 112.458 1.00 38.87 ? 42  LYS C O   1 
ATOM   6687  C CB  . LYS C 1 42  ? 109.189 124.672 113.440 1.00 38.87 ? 42  LYS C CB  1 
ATOM   6688  C CG  . LYS C 1 42  ? 108.602 125.193 114.722 1.00 38.87 ? 42  LYS C CG  1 
ATOM   6689  C CD  . LYS C 1 42  ? 107.312 124.496 115.057 1.00 38.87 ? 42  LYS C CD  1 
ATOM   6690  C CE  . LYS C 1 42  ? 106.919 124.755 116.491 1.00 38.87 ? 42  LYS C CE  1 
ATOM   6691  N NZ  . LYS C 1 42  ? 105.487 125.115 116.601 1.00 38.87 ? 42  LYS C NZ  1 
ATOM   6692  N N   . ARG C 1 43  ? 108.648 127.134 111.544 1.00 39.69 ? 43  ARG C N   1 
ATOM   6693  C CA  . ARG C 1 43  ? 108.261 128.528 111.385 1.00 39.69 ? 43  ARG C CA  1 
ATOM   6694  C C   . ARG C 1 43  ? 107.169 128.682 110.335 1.00 39.69 ? 43  ARG C C   1 
ATOM   6695  O O   . ARG C 1 43  ? 106.201 129.428 110.538 1.00 39.69 ? 43  ARG C O   1 
ATOM   6696  C CB  . ARG C 1 43  ? 109.489 129.349 111.035 1.00 39.69 ? 43  ARG C CB  1 
ATOM   6697  C CG  . ARG C 1 43  ? 110.687 128.937 111.848 1.00 39.69 ? 43  ARG C CG  1 
ATOM   6698  C CD  . ARG C 1 43  ? 111.925 129.709 111.481 1.00 39.69 ? 43  ARG C CD  1 
ATOM   6699  N NE  . ARG C 1 43  ? 111.676 131.143 111.492 1.00 39.69 ? 43  ARG C NE  1 
ATOM   6700  C CZ  . ARG C 1 43  ? 111.583 131.881 112.594 1.00 39.69 ? 43  ARG C CZ  1 
ATOM   6701  N NH1 . ARG C 1 43  ? 111.353 133.183 112.501 1.00 39.69 ? 43  ARG C NH1 1 
ATOM   6702  N NH2 . ARG C 1 43  ? 111.724 131.323 113.788 1.00 39.69 ? 43  ARG C NH2 1 
ATOM   6703  N N   . TRP C 1 44  ? 107.299 127.978 109.212 1.00 35.67 ? 44  TRP C N   1 
ATOM   6704  C CA  . TRP C 1 44  ? 106.216 127.938 108.244 1.00 35.67 ? 44  TRP C CA  1 
ATOM   6705  C C   . TRP C 1 44  ? 104.952 127.383 108.863 1.00 35.67 ? 44  TRP C C   1 
ATOM   6706  O O   . TRP C 1 44  ? 103.857 127.800 108.496 1.00 35.67 ? 44  TRP C O   1 
ATOM   6707  C CB  . TRP C 1 44  ? 106.604 127.090 107.039 1.00 35.67 ? 44  TRP C CB  1 
ATOM   6708  C CG  . TRP C 1 44  ? 107.499 127.745 106.048 1.00 35.67 ? 44  TRP C CG  1 
ATOM   6709  C CD1 . TRP C 1 44  ? 108.709 127.305 105.642 1.00 35.67 ? 44  TRP C CD1 1 
ATOM   6710  C CD2 . TRP C 1 44  ? 107.242 128.940 105.315 1.00 35.67 ? 44  TRP C CD2 1 
ATOM   6711  N NE1 . TRP C 1 44  ? 109.237 128.152 104.712 1.00 35.67 ? 44  TRP C NE1 1 
ATOM   6712  C CE2 . TRP C 1 44  ? 108.351 129.168 104.494 1.00 35.67 ? 44  TRP C CE2 1 
ATOM   6713  C CE3 . TRP C 1 44  ? 106.183 129.844 105.278 1.00 35.67 ? 44  TRP C CE3 1 
ATOM   6714  C CZ2 . TRP C 1 44  ? 108.435 130.257 103.652 1.00 35.67 ? 44  TRP C CZ2 1 
ATOM   6715  C CZ3 . TRP C 1 44  ? 106.268 130.920 104.441 1.00 35.67 ? 44  TRP C CZ3 1 
ATOM   6716  C CH2 . TRP C 1 44  ? 107.384 131.121 103.640 1.00 35.67 ? 44  TRP C CH2 1 
ATOM   6717  N N   . TRP C 1 45  ? 105.072 126.427 109.782 1.00 36.21 ? 45  TRP C N   1 
ATOM   6718  C CA  . TRP C 1 45  ? 103.890 125.932 110.471 1.00 36.21 ? 45  TRP C CA  1 
ATOM   6719  C C   . TRP C 1 45  ? 103.234 127.052 111.249 1.00 36.21 ? 45  TRP C C   1 
ATOM   6720  O O   . TRP C 1 45  ? 102.045 127.329 111.078 1.00 36.21 ? 45  TRP C O   1 
ATOM   6721  C CB  . TRP C 1 45  ? 104.259 124.779 111.405 1.00 36.21 ? 45  TRP C CB  1 
ATOM   6722  C CG  . TRP C 1 45  ? 103.082 124.236 112.173 1.00 36.21 ? 45  TRP C CG  1 
ATOM   6723  C CD1 . TRP C 1 45  ? 102.698 124.578 113.431 1.00 36.21 ? 45  TRP C CD1 1 
ATOM   6724  C CD2 . TRP C 1 45  ? 102.135 123.266 111.719 1.00 36.21 ? 45  TRP C CD2 1 
ATOM   6725  N NE1 . TRP C 1 45  ? 101.576 123.885 113.789 1.00 36.21 ? 45  TRP C NE1 1 
ATOM   6726  C CE2 . TRP C 1 45  ? 101.211 123.071 112.753 1.00 36.21 ? 45  TRP C CE2 1 
ATOM   6727  C CE3 . TRP C 1 45  ? 101.979 122.544 110.536 1.00 36.21 ? 45  TRP C CE3 1 
ATOM   6728  C CZ2 . TRP C 1 45  ? 100.149 122.186 112.641 1.00 36.21 ? 45  TRP C CZ2 1 
ATOM   6729  C CZ3 . TRP C 1 45  ? 100.926 121.668 110.431 1.00 36.21 ? 45  TRP C CZ3 1 
ATOM   6730  C CH2 . TRP C 1 45  ? 100.025 121.496 111.474 1.00 36.21 ? 45  TRP C CH2 1 
ATOM   6731  N N   . ASP C 1 46  ? 104.019 127.731 112.081 1.00 37.28 ? 46  ASP C N   1 
ATOM   6732  C CA  . ASP C 1 46  ? 103.502 128.820 112.897 1.00 37.28 ? 46  ASP C CA  1 
ATOM   6733  C C   . ASP C 1 46  ? 102.782 129.858 112.057 1.00 37.28 ? 46  ASP C C   1 
ATOM   6734  O O   . ASP C 1 46  ? 101.768 130.415 112.482 1.00 37.28 ? 46  ASP C O   1 
ATOM   6735  C CB  . ASP C 1 46  ? 104.642 129.465 113.670 1.00 37.28 ? 46  ASP C CB  1 
ATOM   6736  C CG  . ASP C 1 46  ? 105.219 128.548 114.703 1.00 37.28 ? 46  ASP C CG  1 
ATOM   6737  O OD1 . ASP C 1 46  ? 104.489 127.657 115.174 1.00 37.28 ? 46  ASP C OD1 1 
ATOM   6738  O OD2 . ASP C 1 46  ? 106.402 128.716 115.052 1.00 37.28 ? 46  ASP C OD2 1 
ATOM   6739  N N   . VAL C 1 47  ? 103.291 130.132 110.859 1.00 37.31 ? 47  VAL C N   1 
ATOM   6740  C CA  . VAL C 1 47  ? 102.664 131.138 110.004 1.00 37.31 ? 47  VAL C CA  1 
ATOM   6741  C C   . VAL C 1 47  ? 101.429 130.576 109.310 1.00 37.31 ? 47  VAL C C   1 
ATOM   6742  O O   . VAL C 1 47  ? 100.314 131.073 109.487 1.00 37.31 ? 47  VAL C O   1 
ATOM   6743  C CB  . VAL C 1 47  ? 103.675 131.680 108.983 1.00 37.31 ? 47  VAL C CB  1 
ATOM   6744  C CG1 . VAL C 1 47  ? 103.050 132.790 108.171 1.00 37.31 ? 47  VAL C CG1 1 
ATOM   6745  C CG2 . VAL C 1 47  ? 104.897 132.177 109.691 1.00 37.31 ? 47  VAL C CG2 1 
ATOM   6746  N N   . LEU C 1 48  ? 101.611 129.537 108.503 1.00 36.97 ? 48  LEU C N   1 
ATOM   6747  C CA  . LEU C 1 48  ? 100.557 129.058 107.622 1.00 36.97 ? 48  LEU C CA  1 
ATOM   6748  C C   . LEU C 1 48  ? 99.476  128.315 108.382 1.00 36.97 ? 48  LEU C C   1 
ATOM   6749  O O   . LEU C 1 48  ? 98.289  128.588 108.195 1.00 36.97 ? 48  LEU C O   1 
ATOM   6750  C CB  . LEU C 1 48  ? 101.150 128.145 106.554 1.00 36.97 ? 48  LEU C CB  1 
ATOM   6751  C CG  . LEU C 1 48  ? 102.268 128.709 105.690 1.00 36.97 ? 48  LEU C CG  1 
ATOM   6752  C CD1 . LEU C 1 48  ? 102.733 127.661 104.726 1.00 36.97 ? 48  LEU C CD1 1 
ATOM   6753  C CD2 . LEU C 1 48  ? 101.775 129.915 104.950 1.00 36.97 ? 48  LEU C CD2 1 
ATOM   6754  N N   . ALA C 1 49  ? 99.868  127.348 109.208 1.00 38.32 ? 49  ALA C N   1 
ATOM   6755  C CA  . ALA C 1 49  ? 98.906  126.456 109.844 1.00 38.32 ? 49  ALA C CA  1 
ATOM   6756  C C   . ALA C 1 49  ? 97.745  127.176 110.503 1.00 38.32 ? 49  ALA C C   1 
ATOM   6757  O O   . ALA C 1 49  ? 96.620  126.665 110.417 1.00 38.32 ? 49  ALA C O   1 
ATOM   6758  C CB  . ALA C 1 49  ? 99.635  125.568 110.857 1.00 38.32 ? 49  ALA C CB  1 
ATOM   6759  N N   . PRO C 1 50  ? 97.917  128.324 111.158 1.00 38.15 ? 50  PRO C N   1 
ATOM   6760  C CA  . PRO C 1 50  ? 96.731  129.068 111.592 1.00 38.15 ? 50  PRO C CA  1 
ATOM   6761  C C   . PRO C 1 50  ? 95.837  129.471 110.441 1.00 38.15 ? 50  PRO C C   1 
ATOM   6762  O O   . PRO C 1 50  ? 94.632  129.235 110.496 1.00 38.15 ? 50  PRO C O   1 
ATOM   6763  C CB  . PRO C 1 50  ? 97.331  130.273 112.308 1.00 38.15 ? 50  PRO C CB  1 
ATOM   6764  C CG  . PRO C 1 50  ? 98.614  129.792 112.797 1.00 38.15 ? 50  PRO C CG  1 
ATOM   6765  C CD  . PRO C 1 50  ? 99.139  128.890 111.746 1.00 38.15 ? 50  PRO C CD  1 
ATOM   6766  N N   . VAL C 1 51  ? 96.394  130.062 109.386 1.00 41.07 ? 51  VAL C N   1 
ATOM   6767  C CA  . VAL C 1 51  ? 95.573  130.518 108.264 1.00 41.07 ? 51  VAL C CA  1 
ATOM   6768  C C   . VAL C 1 51  ? 94.870  129.339 107.602 1.00 41.07 ? 51  VAL C C   1 
ATOM   6769  O O   . VAL C 1 51  ? 93.662  129.370 107.344 1.00 41.07 ? 51  VAL C O   1 
ATOM   6770  C CB  . VAL C 1 51  ? 96.440  131.290 107.256 1.00 41.07 ? 51  VAL C CB  1 
ATOM   6771  C CG1 . VAL C 1 51  ? 95.651  131.581 105.998 1.00 41.07 ? 51  VAL C CG1 1 
ATOM   6772  C CG2 . VAL C 1 51  ? 96.970  132.566 107.875 1.00 41.07 ? 51  VAL C CG2 1 
ATOM   6773  N N   . PHE C 1 52  ? 95.626  128.286 107.313 1.00 42.88 ? 52  PHE C N   1 
ATOM   6774  C CA  . PHE C 1 52  ? 95.055  127.100 106.692 1.00 42.88 ? 52  PHE C CA  1 
ATOM   6775  C C   . PHE C 1 52  ? 93.978  126.488 107.574 1.00 42.88 ? 52  PHE C C   1 
ATOM   6776  O O   . PHE C 1 52  ? 92.867  126.207 107.114 1.00 42.88 ? 52  PHE C O   1 
ATOM   6777  C CB  . PHE C 1 52  ? 96.164  126.092 106.415 1.00 42.88 ? 52  PHE C CB  1 
ATOM   6778  C CG  . PHE C 1 52  ? 96.970  126.408 105.197 1.00 42.88 ? 52  PHE C CG  1 
ATOM   6779  C CD1 . PHE C 1 52  ? 96.899  127.652 104.607 1.00 42.88 ? 52  PHE C CD1 1 
ATOM   6780  C CD2 . PHE C 1 52  ? 97.795  125.461 104.634 1.00 42.88 ? 52  PHE C CD2 1 
ATOM   6781  C CE1 . PHE C 1 52  ? 97.636  127.943 103.486 1.00 42.88 ? 52  PHE C CE1 1 
ATOM   6782  C CE2 . PHE C 1 52  ? 98.534  125.754 103.512 1.00 42.88 ? 52  PHE C CE2 1 
ATOM   6783  C CZ  . PHE C 1 52  ? 98.455  126.996 102.942 1.00 42.88 ? 52  PHE C CZ  1 
ATOM   6784  N N   . GLY C 1 53  ? 94.292  126.281 108.852 1.00 43.35 ? 53  GLY C N   1 
ATOM   6785  C CA  . GLY C 1 53  ? 93.338  125.690 109.765 1.00 43.35 ? 53  GLY C CA  1 
ATOM   6786  C C   . GLY C 1 53  ? 92.100  126.531 109.968 1.00 43.35 ? 53  GLY C C   1 
ATOM   6787  O O   . GLY C 1 53  ? 91.017  125.994 110.182 1.00 43.35 ? 53  GLY C O   1 
ATOM   6788  N N   . ILE C 1 54  ? 92.230  127.853 109.879 1.00 45.13 ? 54  ILE C N   1 
ATOM   6789  C CA  . ILE C 1 54  ? 91.066  128.704 110.081 1.00 45.13 ? 54  ILE C CA  1 
ATOM   6790  C C   . ILE C 1 54  ? 90.218  128.762 108.822 1.00 45.13 ? 54  ILE C C   1 
ATOM   6791  O O   . ILE C 1 54  ? 88.993  128.881 108.898 1.00 45.13 ? 54  ILE C O   1 
ATOM   6792  C CB  . ILE C 1 54  ? 91.504  130.099 110.545 1.00 45.13 ? 54  ILE C CB  1 
ATOM   6793  C CG1 . ILE C 1 54  ? 91.976  130.042 111.997 1.00 45.13 ? 54  ILE C CG1 1 
ATOM   6794  C CG2 . ILE C 1 54  ? 90.370  131.093 110.414 1.00 45.13 ? 54  ILE C CG2 1 
ATOM   6795  C CD1 . ILE C 1 54  ? 92.978  131.109 112.363 1.00 45.13 ? 54  ILE C CD1 1 
ATOM   6796  N N   . SER C 1 55  ? 90.835  128.655 107.651 1.00 47.53 ? 55  SER C N   1 
ATOM   6797  C CA  . SER C 1 55  ? 90.046  128.497 106.438 1.00 47.53 ? 55  SER C CA  1 
ATOM   6798  C C   . SER C 1 55  ? 89.301  127.171 106.451 1.00 47.53 ? 55  SER C C   1 
ATOM   6799  O O   . SER C 1 55  ? 88.146  127.088 106.018 1.00 47.53 ? 55  SER C O   1 
ATOM   6800  C CB  . SER C 1 55  ? 90.954  128.594 105.220 1.00 47.53 ? 55  SER C CB  1 
ATOM   6801  O OG  . SER C 1 55  ? 91.591  129.855 105.169 1.00 47.53 ? 55  SER C OG  1 
ATOM   6802  N N   . MET C 1 56  ? 89.957  126.123 106.943 1.00 48.15 ? 56  MET C N   1 
ATOM   6803  C CA  . MET C 1 56  ? 89.317  124.821 107.041 1.00 48.15 ? 56  MET C CA  1 
ATOM   6804  C C   . MET C 1 56  ? 88.177  124.832 108.053 1.00 48.15 ? 56  MET C C   1 
ATOM   6805  O O   . MET C 1 56  ? 87.079  124.349 107.761 1.00 48.15 ? 56  MET C O   1 
ATOM   6806  C CB  . MET C 1 56  ? 90.359  123.773 107.407 1.00 48.15 ? 56  MET C CB  1 
ATOM   6807  C CG  . MET C 1 56  ? 91.472  123.631 106.394 1.00 48.15 ? 56  MET C CG  1 
ATOM   6808  S SD  . MET C 1 56  ? 92.589  122.280 106.808 1.00 48.15 ? 56  MET C SD  1 
ATOM   6809  C CE  . MET C 1 56  ? 93.835  122.452 105.550 1.00 48.15 ? 56  MET C CE  1 
ATOM   6810  N N   . ALA C 1 57  ? 88.410  125.385 109.237 1.00 49.39 ? 57  ALA C N   1 
ATOM   6811  C CA  . ALA C 1 57  ? 87.446  125.372 110.322 1.00 49.39 ? 57  ALA C CA  1 
ATOM   6812  C C   . ALA C 1 57  ? 86.480  126.535 110.266 1.00 49.39 ? 57  ALA C C   1 
ATOM   6813  O O   . ALA C 1 57  ? 85.650  126.677 111.166 1.00 49.39 ? 57  ALA C O   1 
ATOM   6814  C CB  . ALA C 1 57  ? 88.173  125.387 111.665 1.00 49.39 ? 57  ALA C CB  1 
ATOM   6815  N N   . SER C 1 58  ? 86.581  127.382 109.254 1.00 52.76 ? 58  SER C N   1 
ATOM   6816  C CA  . SER C 1 58  ? 85.661  128.489 109.081 1.00 52.76 ? 58  SER C CA  1 
ATOM   6817  C C   . SER C 1 58  ? 84.680  128.239 107.949 1.00 52.76 ? 58  SER C C   1 
ATOM   6818  O O   . SER C 1 58  ? 83.889  129.123 107.614 1.00 52.76 ? 58  SER C O   1 
ATOM   6819  C CB  . SER C 1 58  ? 86.448  129.773 108.855 1.00 52.76 ? 58  SER C CB  1 
ATOM   6820  O OG  . SER C 1 58  ? 87.318  129.613 107.757 1.00 52.76 ? 58  SER C OG  1 
ATOM   6821  N N   . ILE C 1 59  ? 84.732  127.055 107.346 1.00 51.95 ? 59  ILE C N   1 
ATOM   6822  C CA  . ILE C 1 59  ? 83.690  126.574 106.445 1.00 51.95 ? 59  ILE C CA  1 
ATOM   6823  C C   . ILE C 1 59  ? 83.137  125.228 106.880 1.00 51.95 ? 59  ILE C C   1 
ATOM   6824  O O   . ILE C 1 59  ? 82.089  124.814 106.382 1.00 51.95 ? 59  ILE C O   1 
ATOM   6825  C CB  . ILE C 1 59  ? 84.210  126.499 104.999 1.00 51.95 ? 59  ILE C CB  1 
ATOM   6826  C CG1 . ILE C 1 59  ? 85.418  125.576 104.925 1.00 51.95 ? 59  ILE C CG1 1 
ATOM   6827  C CG2 . ILE C 1 59  ? 84.583  127.873 104.495 1.00 51.95 ? 59  ILE C CG2 1 
ATOM   6828  C CD1 . ILE C 1 59  ? 85.929  125.380 103.543 1.00 51.95 ? 59  ILE C CD1 1 
ATOM   6829  N N   . GLY C 1 60  ? 83.813  124.531 107.787 1.00 52.02 ? 60  GLY C N   1 
ATOM   6830  C CA  . GLY C 1 60  ? 83.301  123.323 108.388 1.00 52.02 ? 60  GLY C CA  1 
ATOM   6831  C C   . GLY C 1 60  ? 84.092  122.060 108.141 1.00 52.02 ? 60  GLY C C   1 
ATOM   6832  O O   . GLY C 1 60  ? 83.537  120.971 108.321 1.00 52.02 ? 60  GLY C O   1 
ATOM   6833  N N   . TYR C 1 61  ? 85.356  122.152 107.735 1.00 45.55 ? 61  TYR C N   1 
ATOM   6834  C CA  . TYR C 1 61  ? 86.152  120.941 107.572 1.00 45.55 ? 61  TYR C CA  1 
ATOM   6835  C C   . TYR C 1 61  ? 86.188  120.164 108.881 1.00 45.55 ? 61  TYR C C   1 
ATOM   6836  O O   . TYR C 1 61  ? 86.699  120.658 109.889 1.00 45.55 ? 61  TYR C O   1 
ATOM   6837  C CB  . TYR C 1 61  ? 87.572  121.283 107.123 1.00 45.55 ? 61  TYR C CB  1 
ATOM   6838  C CG  . TYR C 1 61  ? 87.731  121.485 105.633 1.00 45.55 ? 61  TYR C CG  1 
ATOM   6839  C CD1 . TYR C 1 61  ? 86.667  121.903 104.853 1.00 45.55 ? 61  TYR C CD1 1 
ATOM   6840  C CD2 . TYR C 1 61  ? 88.955  121.277 105.009 1.00 45.55 ? 61  TYR C CD2 1 
ATOM   6841  C CE1 . TYR C 1 61  ? 86.812  122.093 103.501 1.00 45.55 ? 61  TYR C CE1 1 
ATOM   6842  C CE2 . TYR C 1 61  ? 89.107  121.474 103.658 1.00 45.55 ? 61  TYR C CE2 1 
ATOM   6843  C CZ  . TYR C 1 61  ? 88.030  121.882 102.910 1.00 45.55 ? 61  TYR C CZ  1 
ATOM   6844  O OH  . TYR C 1 61  ? 88.161  122.081 101.559 1.00 45.55 ? 61  TYR C OH  1 
ATOM   6845  N N   . LYS C 1 62  ? 85.627  118.954 108.864 1.00 46.41 ? 62  LYS C N   1 
ATOM   6846  C CA  . LYS C 1 62  ? 85.529  118.141 110.071 1.00 46.41 ? 62  LYS C CA  1 
ATOM   6847  C C   . LYS C 1 62  ? 86.889  117.976 110.733 1.00 46.41 ? 62  LYS C C   1 
ATOM   6848  O O   . LYS C 1 62  ? 87.914  117.846 110.064 1.00 46.41 ? 62  LYS C O   1 
ATOM   6849  C CB  . LYS C 1 62  ? 84.936  116.776 109.736 1.00 46.41 ? 62  LYS C CB  1 
ATOM   6850  C CG  . LYS C 1 62  ? 83.554  116.850 109.121 1.00 46.41 ? 62  LYS C CG  1 
ATOM   6851  C CD  . LYS C 1 62  ? 83.037  115.472 108.747 1.00 46.41 ? 62  LYS C CD  1 
ATOM   6852  C CE  . LYS C 1 62  ? 81.645  115.544 108.141 1.00 46.41 ? 62  LYS C CE  1 
ATOM   6853  N NZ  . LYS C 1 62  ? 81.602  116.339 106.882 1.00 46.41 ? 62  LYS C NZ  1 
ATOM   6854  N N   . LEU C 1 63  ? 86.884  117.963 112.063 1.00 45.77 ? 63  LEU C N   1 
ATOM   6855  C CA  . LEU C 1 63  ? 88.120  118.130 112.816 1.00 45.77 ? 63  LEU C CA  1 
ATOM   6856  C C   . LEU C 1 63  ? 89.158  117.072 112.476 1.00 45.77 ? 63  LEU C C   1 
ATOM   6857  O O   . LEU C 1 63  ? 90.357  117.372 112.450 1.00 45.77 ? 63  LEU C O   1 
ATOM   6858  C CB  . LEU C 1 63  ? 87.818  118.114 114.308 1.00 45.77 ? 63  LEU C CB  1 
ATOM   6859  C CG  . LEU C 1 63  ? 88.832  118.872 115.154 1.00 45.77 ? 63  LEU C CG  1 
ATOM   6860  C CD1 . LEU C 1 63  ? 88.721  120.326 114.818 1.00 45.77 ? 63  LEU C CD1 1 
ATOM   6861  C CD2 . LEU C 1 63  ? 88.566  118.666 116.619 1.00 45.77 ? 63  LEU C CD2 1 
ATOM   6862  N N   . ASP C 1 64  ? 88.733  115.833 112.218 1.00 46.52 ? 64  ASP C N   1 
ATOM   6863  C CA  . ASP C 1 64  ? 89.697  114.806 111.834 1.00 46.52 ? 64  ASP C CA  1 
ATOM   6864  C C   . ASP C 1 64  ? 90.189  115.031 110.414 1.00 46.52 ? 64  ASP C C   1 
ATOM   6865  O O   . ASP C 1 64  ? 91.335  114.706 110.087 1.00 46.52 ? 64  ASP C O   1 
ATOM   6866  C CB  . ASP C 1 64  ? 89.085  113.421 111.956 1.00 46.52 ? 64  ASP C CB  1 
ATOM   6867  C CG  . ASP C 1 64  ? 88.012  113.179 110.933 1.00 46.52 ? 64  ASP C CG  1 
ATOM   6868  O OD1 . ASP C 1 64  ? 86.928  113.778 111.060 1.00 46.52 ? 64  ASP C OD1 1 
ATOM   6869  O OD2 . ASP C 1 64  ? 88.259  112.408 109.987 1.00 46.52 ? 64  ASP C OD2 1 
ATOM   6870  N N   . VAL C 1 65  ? 89.338  115.598 109.558 1.00 43.61 ? 65  VAL C N   1 
ATOM   6871  C CA  . VAL C 1 65  ? 89.782  115.993 108.229 1.00 43.61 ? 65  VAL C CA  1 
ATOM   6872  C C   . VAL C 1 65  ? 90.761  117.151 108.333 1.00 43.61 ? 65  VAL C C   1 
ATOM   6873  O O   . VAL C 1 65  ? 91.730  117.236 107.572 1.00 43.61 ? 65  VAL C O   1 
ATOM   6874  C CB  . VAL C 1 65  ? 88.571  116.339 107.346 1.00 43.61 ? 65  VAL C CB  1 
ATOM   6875  C CG1 . VAL C 1 65  ? 89.016  116.927 106.039 1.00 43.61 ? 65  VAL C CG1 1 
ATOM   6876  C CG2 . VAL C 1 65  ? 87.727  115.106 107.105 1.00 43.61 ? 65  VAL C CG2 1 
ATOM   6877  N N   . GLN C 1 66  ? 90.528  118.057 109.280 1.00 41.45 ? 66  GLN C N   1 
ATOM   6878  C CA  . GLN C 1 66  ? 91.513  119.088 109.562 1.00 41.45 ? 66  GLN C CA  1 
ATOM   6879  C C   . GLN C 1 66  ? 92.837  118.463 109.954 1.00 41.45 ? 66  GLN C C   1 
ATOM   6880  O O   . GLN C 1 66  ? 93.894  118.858 109.461 1.00 41.45 ? 66  GLN C O   1 
ATOM   6881  C CB  . GLN C 1 66  ? 91.020  120.004 110.674 1.00 41.45 ? 66  GLN C CB  1 
ATOM   6882  C CG  . GLN C 1 66  ? 89.874  120.892 110.312 1.00 41.45 ? 66  GLN C CG  1 
ATOM   6883  C CD  . GLN C 1 66  ? 89.504  121.802 111.451 1.00 41.45 ? 66  GLN C CD  1 
ATOM   6884  O OE1 . GLN C 1 66  ? 90.339  122.144 112.273 1.00 41.45 ? 66  GLN C OE1 1 
ATOM   6885  N NE2 . GLN C 1 66  ? 88.250  122.186 111.514 1.00 41.45 ? 66  GLN C NE2 1 
ATOM   6886  N N   . TYR C 1 67  ? 92.799  117.495 110.867 1.00 42.26 ? 67  TYR C N   1 
ATOM   6887  C CA  . TYR C 1 67  ? 94.022  116.794 111.235 1.00 42.26 ? 67  TYR C CA  1 
ATOM   6888  C C   . TYR C 1 67  ? 94.699  116.186 110.018 1.00 42.26 ? 67  TYR C C   1 
ATOM   6889  O O   . TYR C 1 67  ? 95.916  116.304 109.856 1.00 42.26 ? 67  TYR C O   1 
ATOM   6890  C CB  . TYR C 1 67  ? 93.722  115.716 112.267 1.00 42.26 ? 67  TYR C CB  1 
ATOM   6891  C CG  . TYR C 1 67  ? 93.874  116.177 113.691 1.00 42.26 ? 67  TYR C CG  1 
ATOM   6892  C CD1 . TYR C 1 67  ? 95.103  116.115 114.327 1.00 42.26 ? 67  TYR C CD1 1 
ATOM   6893  C CD2 . TYR C 1 67  ? 92.791  116.666 114.402 1.00 42.26 ? 67  TYR C CD2 1 
ATOM   6894  C CE1 . TYR C 1 67  ? 95.250  116.532 115.627 1.00 42.26 ? 67  TYR C CE1 1 
ATOM   6895  C CE2 . TYR C 1 67  ? 92.929  117.084 115.701 1.00 42.26 ? 67  TYR C CE2 1 
ATOM   6896  C CZ  . TYR C 1 67  ? 94.157  117.013 116.310 1.00 42.26 ? 67  TYR C CZ  1 
ATOM   6897  O OH  . TYR C 1 67  ? 94.296  117.435 117.607 1.00 42.26 ? 67  TYR C OH  1 
ATOM   6898  N N   . ARG C 1 68  ? 93.922  115.546 109.144 1.00 43.36 ? 68  ARG C N   1 
ATOM   6899  C CA  . ARG C 1 68  ? 94.499  114.880 107.980 1.00 43.36 ? 68  ARG C CA  1 
ATOM   6900  C C   . ARG C 1 68  ? 95.171  115.876 107.050 1.00 43.36 ? 68  ARG C C   1 
ATOM   6901  O O   . ARG C 1 68  ? 96.326  115.691 106.655 1.00 43.36 ? 68  ARG C O   1 
ATOM   6902  C CB  . ARG C 1 68  ? 93.422  114.102 107.234 1.00 43.36 ? 68  ARG C CB  1 
ATOM   6903  C CG  . ARG C 1 68  ? 92.929  112.897 107.988 1.00 43.36 ? 68  ARG C CG  1 
ATOM   6904  C CD  . ARG C 1 68  ? 92.103  111.999 107.107 1.00 43.36 ? 68  ARG C CD  1 
ATOM   6905  N NE  . ARG C 1 68  ? 92.897  111.460 106.016 1.00 43.36 ? 68  ARG C NE  1 
ATOM   6906  C CZ  . ARG C 1 68  ? 92.445  110.575 105.140 1.00 43.36 ? 68  ARG C CZ  1 
ATOM   6907  N NH1 . ARG C 1 68  ? 91.201  110.133 105.230 1.00 43.36 ? 68  ARG C NH1 1 
ATOM   6908  N NH2 . ARG C 1 68  ? 93.237  110.136 104.172 1.00 43.36 ? 68  ARG C NH2 1 
ATOM   6909  N N   . HIS C 1 69  ? 94.458  116.936 106.677 1.00 39.41 ? 69  HIS C N   1 
ATOM   6910  C CA  . HIS C 1 69  ? 95.033  117.908 105.755 1.00 39.41 ? 69  HIS C CA  1 
ATOM   6911  C C   . HIS C 1 69  ? 96.210  118.631 106.384 1.00 39.41 ? 69  HIS C C   1 
ATOM   6912  O O   . HIS C 1 69  ? 97.188  118.932 105.702 1.00 39.41 ? 69  HIS C O   1 
ATOM   6913  C CB  . HIS C 1 69  ? 93.974  118.907 105.305 1.00 39.41 ? 69  HIS C CB  1 
ATOM   6914  C CG  . HIS C 1 69  ? 93.063  118.386 104.239 1.00 39.41 ? 69  HIS C CG  1 
ATOM   6915  N ND1 . HIS C 1 69  ? 93.500  117.581 103.213 1.00 39.41 ? 69  HIS C ND1 1 
ATOM   6916  C CD2 . HIS C 1 69  ? 91.738  118.564 104.037 1.00 39.41 ? 69  HIS C CD2 1 
ATOM   6917  C CE1 . HIS C 1 69  ? 92.483  117.284 102.427 1.00 39.41 ? 69  HIS C CE1 1 
ATOM   6918  N NE2 . HIS C 1 69  ? 91.402  117.867 102.905 1.00 39.41 ? 69  HIS C NE2 1 
ATOM   6919  N N   . LEU C 1 70  ? 96.139  118.916 107.682 1.00 38.65 ? 70  LEU C N   1 
ATOM   6920  C CA  . LEU C 1 70  ? 97.247  119.576 108.348 1.00 38.65 ? 70  LEU C CA  1 
ATOM   6921  C C   . LEU C 1 70  ? 98.448  118.660 108.455 1.00 38.65 ? 70  LEU C C   1 
ATOM   6922  O O   . LEU C 1 70  ? 99.584  119.128 108.418 1.00 38.65 ? 70  LEU C O   1 
ATOM   6923  C CB  . LEU C 1 70  ? 96.806  120.056 109.724 1.00 38.65 ? 70  LEU C CB  1 
ATOM   6924  C CG  . LEU C 1 70  ? 95.876  121.264 109.661 1.00 38.65 ? 70  LEU C CG  1 
ATOM   6925  C CD1 . LEU C 1 70  ? 95.128  121.463 110.959 1.00 38.65 ? 70  LEU C CD1 1 
ATOM   6926  C CD2 . LEU C 1 70  ? 96.667  122.491 109.311 1.00 38.65 ? 70  LEU C CD2 1 
ATOM   6927  N N   . LEU C 1 71  ? 98.226  117.354 108.537 1.00 37.24 ? 71  LEU C N   1 
ATOM   6928  C CA  . LEU C 1 71  ? 99.341  116.424 108.533 1.00 37.24 ? 71  LEU C CA  1 
ATOM   6929  C C   . LEU C 1 71  ? 99.906  116.234 107.139 1.00 37.24 ? 71  LEU C C   1 
ATOM   6930  O O   . LEU C 1 71  ? 101.087 115.916 106.993 1.00 37.24 ? 71  LEU C O   1 
ATOM   6931  C CB  . LEU C 1 71  ? 98.899  115.092 109.123 1.00 37.24 ? 71  LEU C CB  1 
ATOM   6932  C CG  . LEU C 1 71  ? 98.678  115.145 110.630 1.00 37.24 ? 71  LEU C CG  1 
ATOM   6933  C CD1 . LEU C 1 71  ? 97.913  113.937 111.073 1.00 37.24 ? 71  LEU C CD1 1 
ATOM   6934  C CD2 . LEU C 1 71  ? 99.994  115.235 111.359 1.00 37.24 ? 71  LEU C CD2 1 
ATOM   6935  N N   . VAL C 1 72  ? 99.082  116.430 106.112 1.00 37.20 ? 72  VAL C N   1 
ATOM   6936  C CA  . VAL C 1 72  ? 99.584  116.443 104.741 1.00 37.20 ? 72  VAL C CA  1 
ATOM   6937  C C   . VAL C 1 72  ? 100.434 117.684 104.508 1.00 37.20 ? 72  VAL C C   1 
ATOM   6938  O O   . VAL C 1 72  ? 101.545 117.611 103.978 1.00 37.20 ? 72  VAL C O   1 
ATOM   6939  C CB  . VAL C 1 72  ? 98.415  116.367 103.744 1.00 37.20 ? 72  VAL C CB  1 
ATOM   6940  C CG1 . VAL C 1 72  ? 98.837  116.894 102.406 1.00 37.20 ? 72  VAL C CG1 1 
ATOM   6941  C CG2 . VAL C 1 72  ? 97.915  114.948 103.605 1.00 37.20 ? 72  VAL C CG2 1 
ATOM   6942  N N   . LEU C 1 73  ? 99.913  118.840 104.903 1.00 34.36 ? 73  LEU C N   1 
ATOM   6943  C CA  . LEU C 1 73  ? 100.670 120.083 104.869 1.00 34.36 ? 73  LEU C CA  1 
ATOM   6944  C C   . LEU C 1 73  ? 101.956 119.975 105.671 1.00 34.36 ? 73  LEU C C   1 
ATOM   6945  O O   . LEU C 1 73  ? 102.986 120.526 105.285 1.00 34.36 ? 73  LEU C O   1 
ATOM   6946  C CB  . LEU C 1 73  ? 99.784  121.211 105.395 1.00 34.36 ? 73  LEU C CB  1 
ATOM   6947  C CG  . LEU C 1 73  ? 100.358 122.464 106.043 1.00 34.36 ? 73  LEU C CG  1 
ATOM   6948  C CD1 . LEU C 1 73  ? 100.894 123.412 105.013 1.00 34.36 ? 73  LEU C CD1 1 
ATOM   6949  C CD2 . LEU C 1 73  ? 99.289  123.140 106.860 1.00 34.36 ? 73  LEU C CD2 1 
ATOM   6950  N N   . TYR C 1 74  ? 101.912 119.265 106.793 1.00 35.67 ? 74  TYR C N   1 
ATOM   6951  C CA  . TYR C 1 74  ? 103.098 119.042 107.603 1.00 35.67 ? 74  TYR C CA  1 
ATOM   6952  C C   . TYR C 1 74  ? 104.054 118.064 106.942 1.00 35.67 ? 74  TYR C C   1 
ATOM   6953  O O   . TYR C 1 74  ? 105.269 118.154 107.140 1.00 35.67 ? 74  TYR C O   1 
ATOM   6954  C CB  . TYR C 1 74  ? 102.665 118.536 108.977 1.00 35.67 ? 74  TYR C CB  1 
ATOM   6955  C CG  . TYR C 1 74  ? 103.638 117.619 109.676 1.00 35.67 ? 74  TYR C CG  1 
ATOM   6956  C CD1 . TYR C 1 74  ? 104.763 118.118 110.301 1.00 35.67 ? 74  TYR C CD1 1 
ATOM   6957  C CD2 . TYR C 1 74  ? 103.409 116.257 109.745 1.00 35.67 ? 74  TYR C CD2 1 
ATOM   6958  C CE1 . TYR C 1 74  ? 105.639 117.293 110.952 1.00 35.67 ? 74  TYR C CE1 1 
ATOM   6959  C CE2 . TYR C 1 74  ? 104.284 115.426 110.394 1.00 35.67 ? 74  TYR C CE2 1 
ATOM   6960  C CZ  . TYR C 1 74  ? 105.398 115.952 110.993 1.00 35.67 ? 74  TYR C CZ  1 
ATOM   6961  O OH  . TYR C 1 74  ? 106.279 115.137 111.647 1.00 35.67 ? 74  TYR C OH  1 
ATOM   6962  N N   . ASP C 1 75  ? 103.528 117.144 106.141 1.00 39.76 ? 75  ASP C N   1 
ATOM   6963  C CA  . ASP C 1 75  ? 104.293 116.042 105.582 1.00 39.76 ? 75  ASP C CA  1 
ATOM   6964  C C   . ASP C 1 75  ? 104.698 116.256 104.135 1.00 39.76 ? 75  ASP C C   1 
ATOM   6965  O O   . ASP C 1 75  ? 105.822 115.921 103.757 1.00 39.76 ? 75  ASP C O   1 
ATOM   6966  C CB  . ASP C 1 75  ? 103.482 114.756 105.684 1.00 39.76 ? 75  ASP C CB  1 
ATOM   6967  C CG  . ASP C 1 75  ? 104.274 113.544 105.281 1.00 39.76 ? 75  ASP C CG  1 
ATOM   6968  O OD1 . ASP C 1 75  ? 105.407 113.384 105.777 1.00 39.76 ? 75  ASP C OD1 1 
ATOM   6969  O OD2 . ASP C 1 75  ? 103.764 112.751 104.466 1.00 39.76 ? 75  ASP C OD2 1 
ATOM   6970  N N   . ALA C 1 76  ? 103.812 116.806 103.312 1.00 36.94 ? 76  ALA C N   1 
ATOM   6971  C CA  . ALA C 1 76  ? 104.042 116.862 101.877 1.00 36.94 ? 76  ALA C CA  1 
ATOM   6972  C C   . ALA C 1 76  ? 104.479 118.235 101.383 1.00 36.94 ? 76  ALA C C   1 
ATOM   6973  O O   . ALA C 1 76  ? 105.464 118.333 100.649 1.00 36.94 ? 76  ALA C O   1 
ATOM   6974  C CB  . ALA C 1 76  ? 102.780 116.417 101.133 1.00 36.94 ? 76  ALA C CB  1 
ATOM   6975  N N   . VAL C 1 77  ? 103.782 119.302 101.758 1.00 34.25 ? 77  VAL C N   1 
ATOM   6976  C CA  . VAL C 1 77  ? 103.960 120.581 101.094 1.00 34.25 ? 77  VAL C CA  1 
ATOM   6977  C C   . VAL C 1 77  ? 104.957 121.475 101.822 1.00 34.25 ? 77  VAL C C   1 
ATOM   6978  O O   . VAL C 1 77  ? 105.714 122.198 101.179 1.00 34.25 ? 77  VAL C O   1 
ATOM   6979  C CB  . VAL C 1 77  ? 102.602 121.289 100.901 1.00 34.25 ? 77  VAL C CB  1 
ATOM   6980  C CG1 . VAL C 1 77  ? 101.542 120.291 100.504 1.00 34.25 ? 77  VAL C CG1 1 
ATOM   6981  C CG2 . VAL C 1 77  ? 102.197 122.041 102.111 1.00 34.25 ? 77  VAL C CG2 1 
ATOM   6982  N N   . ILE C 1 78  ? 104.995 121.447 103.148 1.00 32.07 ? 78  ILE C N   1 
ATOM   6983  C CA  . ILE C 1 78  ? 105.888 122.343 103.877 1.00 32.07 ? 78  ILE C CA  1 
ATOM   6984  C C   . ILE C 1 78  ? 107.336 121.916 103.678 1.00 32.07 ? 78  ILE C C   1 
ATOM   6985  O O   . ILE C 1 78  ? 108.197 122.784 103.494 1.00 32.07 ? 78  ILE C O   1 
ATOM   6986  C CB  . ILE C 1 78  ? 105.535 122.425 105.368 1.00 32.07 ? 78  ILE C CB  1 
ATOM   6987  C CG1 . ILE C 1 78  ? 104.434 123.448 105.604 1.00 32.07 ? 78  ILE C CG1 1 
ATOM   6988  C CG2 . ILE C 1 78  ? 106.721 122.857 106.152 1.00 32.07 ? 78  ILE C CG2 1 
ATOM   6989  C CD1 . ILE C 1 78  ? 104.024 123.567 107.032 1.00 32.07 ? 78  ILE C CD1 1 
ATOM   6990  N N   . PRO C 1 79  ? 107.674 120.626 103.694 1.00 31.87 ? 79  PRO C N   1 
ATOM   6991  C CA  . PRO C 1 79  ? 109.053 120.254 103.364 1.00 31.87 ? 79  PRO C CA  1 
ATOM   6992  C C   . PRO C 1 79  ? 109.429 120.588 101.934 1.00 31.87 ? 79  PRO C C   1 
ATOM   6993  O O   . PRO C 1 79  ? 110.605 120.512 101.571 1.00 31.87 ? 79  PRO C O   1 
ATOM   6994  C CB  . PRO C 1 79  ? 109.074 118.746 103.612 1.00 31.87 ? 79  PRO C CB  1 
ATOM   6995  C CG  . PRO C 1 79  ? 108.008 118.526 104.578 1.00 31.87 ? 79  PRO C CG  1 
ATOM   6996  C CD  . PRO C 1 79  ? 106.936 119.474 104.233 1.00 31.87 ? 79  PRO C CD  1 
ATOM   6997  N N   . ASN C 1 80  ? 108.449 120.969 101.120 1.00 36.45 ? 80  ASN C N   1 
ATOM   6998  C CA  . ASN C 1 80  ? 108.652 121.336 99.725  1.00 36.45 ? 80  ASN C CA  1 
ATOM   6999  C C   . ASN C 1 80  ? 108.241 122.779 99.477  1.00 36.45 ? 80  ASN C C   1 
ATOM   7000  O O   . ASN C 1 80  ? 107.635 123.092 98.453  1.00 36.45 ? 80  ASN C O   1 
ATOM   7001  C CB  . ASN C 1 80  ? 107.879 120.400 98.800  1.00 36.45 ? 80  ASN C CB  1 
ATOM   7002  C CG  . ASN C 1 80  ? 108.326 118.966 98.923  1.00 36.45 ? 80  ASN C CG  1 
ATOM   7003  O OD1 . ASN C 1 80  ? 109.448 118.625 98.562  1.00 36.45 ? 80  ASN C OD1 1 
ATOM   7004  N ND2 . ASN C 1 80  ? 107.451 118.115 99.438  1.00 36.45 ? 80  ASN C ND2 1 
ATOM   7005  N N   . MET C 1 81  ? 108.546 123.663 100.419 1.00 36.49 ? 81  MET C N   1 
ATOM   7006  C CA  . MET C 1 81  ? 108.192 125.066 100.314 1.00 36.49 ? 81  MET C CA  1 
ATOM   7007  C C   . MET C 1 81  ? 109.405 125.973 100.248 1.00 36.49 ? 81  MET C C   1 
ATOM   7008  O O   . MET C 1 81  ? 109.275 127.133 99.848  1.00 36.49 ? 81  MET C O   1 
ATOM   7009  C CB  . MET C 1 81  ? 107.317 125.475 101.500 1.00 36.49 ? 81  MET C CB  1 
ATOM   7010  C CG  . MET C 1 81  ? 106.553 126.747 101.289 1.00 36.49 ? 81  MET C CG  1 
ATOM   7011  S SD  . MET C 1 81  ? 105.131 126.850 102.357 1.00 36.49 ? 81  MET C SD  1 
ATOM   7012  C CE  . MET C 1 81  ? 104.245 125.401 101.836 1.00 36.49 ? 81  MET C CE  1 
ATOM   7013  N N   . GLY C 1 82  ? 110.576 125.475 100.606 1.00 37.48 ? 82  GLY C N   1 
ATOM   7014  C CA  . GLY C 1 82  ? 111.768 126.277 100.570 1.00 37.48 ? 82  GLY C CA  1 
ATOM   7015  C C   . GLY C 1 82  ? 111.943 127.006 101.874 1.00 37.48 ? 82  GLY C C   1 
ATOM   7016  O O   . GLY C 1 82  ? 111.095 126.935 102.765 1.00 37.48 ? 82  GLY C O   1 
ATOM   7017  N N   . PRO C 1 83  ? 113.041 127.736 102.010 1.00 41.02 ? 83  PRO C N   1 
ATOM   7018  C CA  . PRO C 1 83  ? 113.370 128.326 103.307 1.00 41.02 ? 83  PRO C CA  1 
ATOM   7019  C C   . PRO C 1 83  ? 112.392 129.420 103.695 1.00 41.02 ? 83  PRO C C   1 
ATOM   7020  O O   . PRO C 1 83  ? 111.618 129.913 102.875 1.00 41.02 ? 83  PRO C O   1 
ATOM   7021  C CB  . PRO C 1 83  ? 114.778 128.879 103.093 1.00 41.02 ? 83  PRO C CB  1 
ATOM   7022  C CG  . PRO C 1 83  ? 114.861 129.114 101.648 1.00 41.02 ? 83  PRO C CG  1 
ATOM   7023  C CD  . PRO C 1 83  ? 114.040 128.061 100.987 1.00 41.02 ? 83  PRO C CD  1 
ATOM   7024  N N   . PHE C 1 84  ? 112.402 129.816 104.986 1.00 40.38 ? 84  PHE C N   1 
ATOM   7025  C CA  . PHE C 1 84  ? 111.429 130.810 105.562 1.00 40.38 ? 84  PHE C CA  1 
ATOM   7026  C C   . PHE C 1 84  ? 111.948 132.201 105.451 1.00 40.38 ? 84  PHE C C   1 
ATOM   7027  O O   . PHE C 1 84  ? 113.122 132.448 105.643 1.00 40.38 ? 84  PHE C O   1 
ATOM   7028  C CB  . PHE C 1 84  ? 111.129 130.479 107.036 1.00 40.38 ? 84  PHE C CB  1 
ATOM   7029  C CG  . PHE C 1 84  ? 110.117 131.362 107.679 1.00 40.38 ? 84  PHE C CG  1 
ATOM   7030  C CD1 . PHE C 1 84  ? 108.792 131.194 107.423 1.00 40.38 ? 84  PHE C CD1 1 
ATOM   7031  C CD2 . PHE C 1 84  ? 110.497 132.336 108.563 1.00 40.38 ? 84  PHE C CD2 1 
ATOM   7032  C CE1 . PHE C 1 84  ? 107.857 131.998 108.000 1.00 40.38 ? 84  PHE C CE1 1 
ATOM   7033  C CE2 . PHE C 1 84  ? 109.563 133.149 109.152 1.00 40.38 ? 84  PHE C CE2 1 
ATOM   7034  C CZ  . PHE C 1 84  ? 108.240 132.978 108.868 1.00 40.38 ? 84  PHE C CZ  1 
ATOM   7035  N N   . PRO C 1 85  ? 111.065 133.141 105.144 1.00 42.25 ? 85  PRO C N   1 
ATOM   7036  C CA  . PRO C 1 85  ? 111.694 134.406 104.943 1.00 42.25 ? 85  PRO C CA  1 
ATOM   7037  C C   . PRO C 1 85  ? 112.228 134.985 106.214 1.00 42.25 ? 85  PRO C C   1 
ATOM   7038  O O   . PRO C 1 85  ? 111.498 135.197 107.156 1.00 42.25 ? 85  PRO C O   1 
ATOM   7039  C CB  . PRO C 1 85  ? 110.567 135.240 104.403 1.00 42.25 ? 85  PRO C CB  1 
ATOM   7040  C CG  . PRO C 1 85  ? 109.321 134.539 104.741 1.00 42.25 ? 85  PRO C CG  1 
ATOM   7041  C CD  . PRO C 1 85  ? 109.703 133.127 104.630 1.00 42.25 ? 85  PRO C CD  1 
ATOM   7042  N N   . ASN C 1 86  ? 113.494 135.304 106.246 1.00 53.56 ? 86  ASN C N   1 
ATOM   7043  C CA  . ASN C 1 86  ? 114.029 135.975 107.398 1.00 53.56 ? 86  ASN C CA  1 
ATOM   7044  C C   . ASN C 1 86  ? 113.779 137.478 107.265 1.00 53.56 ? 86  ASN C C   1 
ATOM   7045  O O   . ASN C 1 86  ? 113.127 137.903 106.333 1.00 53.56 ? 86  ASN C O   1 
ATOM   7046  C CB  . ASN C 1 86  ? 115.480 135.560 107.756 1.00 53.56 ? 86  ASN C CB  1 
ATOM   7047  C CG  . ASN C 1 86  ? 116.538 136.120 106.825 1.00 53.56 ? 86  ASN C CG  1 
ATOM   7048  O OD1 . ASN C 1 86  ? 116.391 137.176 106.233 1.00 53.56 ? 86  ASN C OD1 1 
ATOM   7049  N ND2 . ASN C 1 86  ? 117.650 135.414 106.739 1.00 53.56 ? 86  ASN C ND2 1 
ATOM   7050  N N   . SER C 1 87  ? 114.280 138.294 108.174 1.00 59.25 ? 87  SER C N   1 
ATOM   7051  C CA  . SER C 1 87  ? 113.985 139.729 108.187 1.00 59.25 ? 87  SER C CA  1 
ATOM   7052  C C   . SER C 1 87  ? 114.372 140.555 106.984 1.00 59.25 ? 87  SER C C   1 
ATOM   7053  O O   . SER C 1 87  ? 113.628 141.428 106.558 1.00 59.25 ? 87  SER C O   1 
ATOM   7054  C CB  . SER C 1 87  ? 114.723 140.313 109.362 1.00 59.25 ? 87  SER C CB  1 
ATOM   7055  O OG  . SER C 1 87  ? 116.109 140.051 109.256 1.00 59.25 ? 87  SER C OG  1 
ATOM   7056  N N   . ASN C 1 88  ? 115.539 140.308 106.438 1.00 59.02 ? 88  ASN C N   1 
ATOM   7057  C CA  . ASN C 1 88  ? 115.930 140.999 105.247 1.00 59.02 ? 88  ASN C CA  1 
ATOM   7058  C C   . ASN C 1 88  ? 115.715 140.059 104.092 1.00 59.02 ? 88  ASN C C   1 
ATOM   7059  O O   . ASN C 1 88  ? 116.179 140.348 102.999 1.00 59.02 ? 88  ASN C O   1 
ATOM   7060  C CB  . ASN C 1 88  ? 117.383 141.445 105.323 1.00 59.02 ? 88  ASN C CB  1 
ATOM   7061  C CG  . ASN C 1 88  ? 118.302 140.435 105.973 1.00 59.02 ? 88  ASN C CG  1 
ATOM   7062  O OD1 . ASN C 1 88  ? 117.946 139.752 106.924 1.00 59.02 ? 88  ASN C OD1 1 
ATOM   7063  N ND2 . ASN C 1 88  ? 119.531 140.388 105.490 1.00 59.02 ? 88  ASN C ND2 1 
ATOM   7064  N N   . ALA C 1 89  ? 115.006 138.950 104.303 1.00 55.52 ? 89  ALA C N   1 
ATOM   7065  C CA  . ALA C 1 89  ? 114.860 137.906 103.274 1.00 55.52 ? 89  ALA C CA  1 
ATOM   7066  C C   . ALA C 1 89  ? 116.211 137.649 102.659 1.00 55.52 ? 89  ALA C C   1 
ATOM   7067  O O   . ALA C 1 89  ? 116.352 137.587 101.459 1.00 55.52 ? 89  ALA C O   1 
ATOM   7068  C CB  . ALA C 1 89  ? 113.818 138.223 102.244 1.00 55.52 ? 89  ALA C CB  1 
ATOM   7069  N N   . SER C 1 90  ? 117.208 137.510 103.501 1.00 55.46 ? 90  SER C N   1 
ATOM   7070  C CA  . SER C 1 90  ? 118.560 137.230 103.037 1.00 55.46 ? 90  SER C CA  1 
ATOM   7071  C C   . SER C 1 90  ? 118.713 135.791 102.575 1.00 55.46 ? 90  SER C C   1 
ATOM   7072  O O   . SER C 1 90  ? 119.501 135.512 101.667 1.00 55.46 ? 90  SER C O   1 
ATOM   7073  C CB  . SER C 1 90  ? 119.558 137.533 104.151 1.00 55.46 ? 90  SER C CB  1 
ATOM   7074  O OG  . SER C 1 90  ? 120.864 137.143 103.780 1.00 55.46 ? 90  SER C OG  1 
ATOM   7075  N N   . ASN C 1 91  ? 117.970 134.869 103.186 1.00 51.12 ? 91  ASN C N   1 
ATOM   7076  C CA  . ASN C 1 91  ? 118.127 133.451 102.905 1.00 51.12 ? 91  ASN C CA  1 
ATOM   7077  C C   . ASN C 1 91  ? 117.432 133.014 101.627 1.00 51.12 ? 91  ASN C C   1 
ATOM   7078  O O   . ASN C 1 91  ? 117.745 131.940 101.109 1.00 51.12 ? 91  ASN C O   1 
ATOM   7079  C CB  . ASN C 1 91  ? 117.593 132.635 104.076 1.00 51.12 ? 91  ASN C CB  1 
ATOM   7080  C CG  . ASN C 1 91  ? 116.139 132.918 104.356 1.00 51.12 ? 91  ASN C CG  1 
ATOM   7081  O OD1 . ASN C 1 91  ? 115.562 133.845 103.794 1.00 51.12 ? 91  ASN C OD1 1 
ATOM   7082  N ND2 . ASN C 1 91  ? 115.536 132.126 105.230 1.00 51.12 ? 91  ASN C ND2 1 
ATOM   7083  N N   . ILE C 1 92  ? 116.494 133.803 101.113 1.00 47.25 ? 92  ILE C N   1 
ATOM   7084  C CA  . ILE C 1 92  ? 115.768 133.441 99.901  1.00 47.25 ? 92  ILE C CA  1 
ATOM   7085  C C   . ILE C 1 92  ? 116.724 133.536 98.717  1.00 47.25 ? 92  ILE C C   1 
ATOM   7086  O O   . ILE C 1 92  ? 117.086 134.633 98.289  1.00 47.25 ? 92  ILE C O   1 
ATOM   7087  C CB  . ILE C 1 92  ? 114.549 134.341 99.697  1.00 47.25 ? 92  ILE C CB  1 
ATOM   7088  C CG1 . ILE C 1 92  ? 113.609 134.230 100.895 1.00 47.25 ? 92  ILE C CG1 1 
ATOM   7089  C CG2 . ILE C 1 92  ? 113.848 133.990 98.416  1.00 47.25 ? 92  ILE C CG2 1 
ATOM   7090  C CD1 . ILE C 1 92  ? 113.030 132.860 101.105 1.00 47.25 ? 92  ILE C CD1 1 
ATOM   7091  N N   . THR C 1 93  ? 117.128 132.389 98.175  1.00 44.32 ? 93  THR C N   1 
ATOM   7092  C CA  . THR C 1 93  ? 118.034 132.356 97.038  1.00 44.32 ? 93  THR C CA  1 
ATOM   7093  C C   . THR C 1 93  ? 117.352 132.017 95.725  1.00 44.32 ? 93  THR C C   1 
ATOM   7094  O O   . THR C 1 93  ? 117.978 132.157 94.672  1.00 44.32 ? 93  THR C O   1 
ATOM   7095  C CB  . THR C 1 93  ? 119.163 131.349 97.275  1.00 44.32 ? 93  THR C CB  1 
ATOM   7096  O OG1 . THR C 1 93  ? 118.653 130.026 97.118  1.00 44.32 ? 93  THR C OG1 1 
ATOM   7097  C CG2 . THR C 1 93  ? 119.721 131.497 98.665  1.00 44.32 ? 93  THR C CG2 1 
ATOM   7098  N N   . TRP C 1 94  ? 116.103 131.574 95.751  1.00 41.75 ? 94  TRP C N   1 
ATOM   7099  C CA  . TRP C 1 94  ? 115.355 131.251 94.540  1.00 41.75 ? 94  TRP C CA  1 
ATOM   7100  C C   . TRP C 1 94  ? 114.495 132.464 94.212  1.00 41.75 ? 94  TRP C C   1 
ATOM   7101  O O   . TRP C 1 94  ? 113.381 132.611 94.707  1.00 41.75 ? 94  TRP C O   1 
ATOM   7102  C CB  . TRP C 1 94  ? 114.527 129.994 94.747  1.00 41.75 ? 94  TRP C CB  1 
ATOM   7103  C CG  . TRP C 1 94  ? 113.610 129.653 93.628  1.00 41.75 ? 94  TRP C CG  1 
ATOM   7104  C CD1 . TRP C 1 94  ? 112.266 129.831 93.596  1.00 41.75 ? 94  TRP C CD1 1 
ATOM   7105  C CD2 . TRP C 1 94  ? 113.962 129.046 92.384  1.00 41.75 ? 94  TRP C CD2 1 
ATOM   7106  N NE1 . TRP C 1 94  ? 111.758 129.385 92.407  1.00 41.75 ? 94  TRP C NE1 1 
ATOM   7107  C CE2 . TRP C 1 94  ? 112.783 128.899 91.643  1.00 41.75 ? 94  TRP C CE2 1 
ATOM   7108  C CE3 . TRP C 1 94  ? 115.163 128.618 91.823  1.00 41.75 ? 94  TRP C CE3 1 
ATOM   7109  C CZ2 . TRP C 1 94  ? 112.769 128.344 90.373  1.00 41.75 ? 94  TRP C CZ2 1 
ATOM   7110  C CZ3 . TRP C 1 94  ? 115.146 128.070 90.566  1.00 41.75 ? 94  TRP C CZ3 1 
ATOM   7111  C CH2 . TRP C 1 94  ? 113.960 127.938 89.854  1.00 41.75 ? 94  TRP C CH2 1 
ATOM   7112  N N   . THR C 1 95  ? 115.022 133.330 93.353  1.00 47.26 ? 95  THR C N   1 
ATOM   7113  C CA  . THR C 1 95  ? 114.446 134.645 93.122  1.00 47.26 ? 95  THR C CA  1 
ATOM   7114  C C   . THR C 1 95  ? 113.042 134.552 92.542  1.00 47.26 ? 95  THR C C   1 
ATOM   7115  O O   . THR C 1 95  ? 112.626 133.526 92.011  1.00 47.26 ? 95  THR C O   1 
ATOM   7116  C CB  . THR C 1 95  ? 115.328 135.439 92.174  1.00 47.26 ? 95  THR C CB  1 
ATOM   7117  O OG1 . THR C 1 95  ? 115.170 134.924 90.849  1.00 47.26 ? 95  THR C OG1 1 
ATOM   7118  C CG2 . THR C 1 95  ? 116.777 135.303 92.582  1.00 47.26 ? 95  THR C CG2 1 
ATOM   7119  N N   . SER C 1 96  ? 112.316 135.661 92.637  1.00 50.81 ? 96  SER C N   1 
ATOM   7120  C CA  . SER C 1 96  ? 110.924 135.724 92.214  1.00 50.81 ? 96  SER C CA  1 
ATOM   7121  C C   . SER C 1 96  ? 110.399 137.153 92.275  1.00 50.81 ? 96  SER C C   1 
ATOM   7122  O O   . SER C 1 96  ? 110.889 137.964 93.069  1.00 50.81 ? 96  SER C O   1 
ATOM   7123  C CB  . SER C 1 96  ? 110.063 134.817 93.094  1.00 50.81 ? 96  SER C CB  1 
ATOM   7124  O OG  . SER C 1 96  ? 108.696 134.904 92.749  1.00 50.81 ? 96  SER C OG  1 
ATOM   7125  N N   . PRO C 1 97  ? 109.407 137.503 91.453  1.00 52.00 ? 97  PRO C N   1 
ATOM   7126  C CA  . PRO C 1 97  ? 108.720 138.786 91.627  1.00 52.00 ? 97  PRO C CA  1 
ATOM   7127  C C   . PRO C 1 97  ? 107.682 138.780 92.735  1.00 52.00 ? 97  PRO C C   1 
ATOM   7128  O O   . PRO C 1 97  ? 107.109 139.838 93.026  1.00 52.00 ? 97  PRO C O   1 
ATOM   7129  C CB  . PRO C 1 97  ? 108.048 139.013 90.263  1.00 52.00 ? 97  PRO C CB  1 
ATOM   7130  C CG  . PRO C 1 97  ? 108.585 137.950 89.360  1.00 52.00 ? 97  PRO C CG  1 
ATOM   7131  C CD  . PRO C 1 97  ? 108.975 136.821 90.229  1.00 52.00 ? 97  PRO C CD  1 
ATOM   7132  N N   . PHE C 1 98  ? 107.407 137.637 93.343  1.00 51.63 ? 98  PHE C N   1 
ATOM   7133  C CA  . PHE C 1 98  ? 106.463 137.522 94.439  1.00 51.63 ? 98  PHE C CA  1 
ATOM   7134  C C   . PHE C 1 98  ? 107.193 137.258 95.744  1.00 51.63 ? 98  PHE C C   1 
ATOM   7135  O O   . PHE C 1 98  ? 108.363 136.869 95.747  1.00 51.63 ? 98  PHE C O   1 
ATOM   7136  C CB  . PHE C 1 98  ? 105.467 136.395 94.163  1.00 51.63 ? 98  PHE C CB  1 
ATOM   7137  C CG  . PHE C 1 98  ? 105.065 136.292 92.732  1.00 51.63 ? 98  PHE C CG  1 
ATOM   7138  C CD1 . PHE C 1 98  ? 104.441 137.345 92.100  1.00 51.63 ? 98  PHE C CD1 1 
ATOM   7139  C CD2 . PHE C 1 98  ? 105.312 135.142 92.015  1.00 51.63 ? 98  PHE C CD2 1 
ATOM   7140  C CE1 . PHE C 1 98  ? 104.071 137.250 90.783  1.00 51.63 ? 98  PHE C CE1 1 
ATOM   7141  C CE2 . PHE C 1 98  ? 104.943 135.042 90.695  1.00 51.63 ? 98  PHE C CE2 1 
ATOM   7142  C CZ  . PHE C 1 98  ? 104.324 136.096 90.079  1.00 51.63 ? 98  PHE C CZ  1 
ATOM   7143  N N   . PRO C 1 99  ? 106.542 137.478 96.882  1.00 49.26 ? 99  PRO C N   1 
ATOM   7144  C CA  . PRO C 1 99  ? 107.166 137.150 98.163  1.00 49.26 ? 99  PRO C CA  1 
ATOM   7145  C C   . PRO C 1 99  ? 107.242 135.649 98.362  1.00 49.26 ? 99  PRO C C   1 
ATOM   7146  O O   . PRO C 1 99  ? 106.477 134.892 97.747  1.00 49.26 ? 99  PRO C O   1 
ATOM   7147  C CB  . PRO C 1 99  ? 106.230 137.805 99.187  1.00 49.26 ? 99  PRO C CB  1 
ATOM   7148  C CG  . PRO C 1 99  ? 104.938 137.929 98.485  1.00 49.26 ? 99  PRO C CG  1 
ATOM   7149  C CD  . PRO C 1 99  ? 105.277 138.208 97.065  1.00 49.26 ? 99  PRO C CD  1 
ATOM   7150  N N   . PRO C 1 100 ? 108.154 135.178 99.207  1.00 45.40 ? 100 PRO C N   1 
ATOM   7151  C CA  . PRO C 1 100 ? 108.290 133.734 99.420  1.00 45.40 ? 100 PRO C CA  1 
ATOM   7152  C C   . PRO C 1 100 ? 107.046 133.125 100.044 1.00 45.40 ? 100 PRO C C   1 
ATOM   7153  O O   . PRO C 1 100 ? 106.232 133.807 100.668 1.00 45.40 ? 100 PRO C O   1 
ATOM   7154  C CB  . PRO C 1 100 ? 109.490 133.626 100.363 1.00 45.40 ? 100 PRO C CB  1 
ATOM   7155  C CG  . PRO C 1 100 ? 110.234 134.867 100.153 1.00 45.40 ? 100 PRO C CG  1 
ATOM   7156  C CD  . PRO C 1 100 ? 109.228 135.928 99.867  1.00 45.40 ? 100 PRO C CD  1 
ATOM   7157  N N   . GLY C 1 101 ? 106.909 131.819 99.869  1.00 41.59 ? 101 GLY C N   1 
ATOM   7158  C CA  . GLY C 1 101 ? 105.777 131.100 100.385 1.00 41.59 ? 101 GLY C CA  1 
ATOM   7159  C C   . GLY C 1 101 ? 104.808 130.770 99.281  1.00 41.59 ? 101 GLY C C   1 
ATOM   7160  O O   . GLY C 1 101 ? 105.121 130.885 98.096  1.00 41.59 ? 101 GLY C O   1 
ATOM   7161  N N   . PRO C 1 102 ? 103.610 130.342 99.649  1.00 38.99 ? 102 PRO C N   1 
ATOM   7162  C CA  . PRO C 1 102 ? 102.597 130.056 98.637  1.00 38.99 ? 102 PRO C CA  1 
ATOM   7163  C C   . PRO C 1 102 ? 102.329 131.269 97.767  1.00 38.99 ? 102 PRO C C   1 
ATOM   7164  O O   . PRO C 1 102 ? 102.431 132.413 98.207  1.00 38.99 ? 102 PRO C O   1 
ATOM   7165  C CB  . PRO C 1 102 ? 101.367 129.686 99.465  1.00 38.99 ? 102 PRO C CB  1 
ATOM   7166  C CG  . PRO C 1 102 ? 101.910 129.216 100.733 1.00 38.99 ? 102 PRO C CG  1 
ATOM   7167  C CD  . PRO C 1 102 ? 103.161 129.978 100.996 1.00 38.99 ? 102 PRO C CD  1 
ATOM   7168  N N   . LEU C 1 103 ? 102.000 131.006 96.510  1.00 41.81 ? 103 LEU C N   1 
ATOM   7169  C CA  . LEU C 1 103 ? 101.547 132.069 95.636  1.00 41.81 ? 103 LEU C CA  1 
ATOM   7170  C C   . LEU C 1 103 ? 100.177 132.569 96.035  1.00 41.81 ? 103 LEU C C   1 
ATOM   7171  O O   . LEU C 1 103 ? 99.793  133.672 95.641  1.00 41.81 ? 103 LEU C O   1 
ATOM   7172  C CB  . LEU C 1 103 ? 101.504 131.591 94.190  1.00 41.81 ? 103 LEU C CB  1 
ATOM   7173  C CG  . LEU C 1 103 ? 102.833 131.139 93.599  1.00 41.81 ? 103 LEU C CG  1 
ATOM   7174  C CD1 . LEU C 1 103 ? 102.636 130.679 92.174  1.00 41.81 ? 103 LEU C CD1 1 
ATOM   7175  C CD2 . LEU C 1 103 ? 103.851 132.243 93.672  1.00 41.81 ? 103 LEU C CD2 1 
ATOM   7176  N N   . GLU C 1 104 ? 99.444  131.786 96.812  1.00 47.72 ? 104 GLU C N   1 
ATOM   7177  C CA  . GLU C 1 104 ? 98.104  132.154 97.232  1.00 47.72 ? 104 GLU C CA  1 
ATOM   7178  C C   . GLU C 1 104 ? 97.600  131.083 98.187  1.00 47.72 ? 104 GLU C C   1 
ATOM   7179  O O   . GLU C 1 104 ? 98.144  129.980 98.260  1.00 47.72 ? 104 GLU C O   1 
ATOM   7180  C CB  . GLU C 1 104 ? 97.161  132.284 96.043  1.00 47.72 ? 104 GLU C CB  1 
ATOM   7181  C CG  . GLU C 1 104 ? 96.895  130.956 95.370  1.00 47.72 ? 104 GLU C CG  1 
ATOM   7182  C CD  . GLU C 1 104 ? 96.744  131.082 93.875  1.00 47.72 ? 104 GLU C CD  1 
ATOM   7183  O OE1 . GLU C 1 104 ? 96.906  132.197 93.352  1.00 47.72 ? 104 GLU C OE1 1 
ATOM   7184  O OE2 . GLU C 1 104 ? 96.454  130.068 93.213  1.00 47.72 ? 104 GLU C OE2 1 
ATOM   7185  N N   . ALA C 1 105 ? 96.568  131.441 98.938  1.00 45.49 ? 105 ALA C N   1 
ATOM   7186  C CA  . ALA C 1 105 ? 95.727  130.499 99.656  1.00 45.49 ? 105 ALA C CA  1 
ATOM   7187  C C   . ALA C 1 105 ? 94.315  130.874 99.279  1.00 45.49 ? 105 ALA C C   1 
ATOM   7188  O O   . ALA C 1 105 ? 93.857  131.967 99.611  1.00 45.49 ? 105 ALA C O   1 
ATOM   7189  C CB  . ALA C 1 105 ? 95.933  130.578 101.166 1.00 45.49 ? 105 ALA C CB  1 
ATOM   7190  N N   . SER C 1 106 ? 93.632  129.986 98.594  1.00 47.99 ? 106 SER C N   1 
ATOM   7191  C CA  . SER C 1 106 ? 92.665  130.403 97.596  1.00 47.99 ? 106 SER C CA  1 
ATOM   7192  C C   . SER C 1 106 ? 91.276  129.827 97.810  1.00 47.99 ? 106 SER C C   1 
ATOM   7193  O O   . SER C 1 106 ? 90.699  129.221 96.911  1.00 47.99 ? 106 SER C O   1 
ATOM   7194  C CB  . SER C 1 106 ? 93.204  130.080 96.209  1.00 47.99 ? 106 SER C CB  1 
ATOM   7195  O OG  . SER C 1 106 ? 93.679  128.755 96.118  1.00 47.99 ? 106 SER C OG  1 
ATOM   7196  N N   . VAL C 1 107 ? 90.726  130.027 99.002  1.00 54.47 ? 107 VAL C N   1 
ATOM   7197  C CA  . VAL C 1 107 ? 89.344  129.662 99.283  1.00 54.47 ? 107 VAL C CA  1 
ATOM   7198  C C   . VAL C 1 107 ? 88.455  130.127 98.142  1.00 54.47 ? 107 VAL C C   1 
ATOM   7199  O O   . VAL C 1 107 ? 88.413  131.317 97.816  1.00 54.47 ? 107 VAL C O   1 
ATOM   7200  C CB  . VAL C 1 107 ? 88.862  130.281 100.604 1.00 54.47 ? 107 VAL C CB  1 
ATOM   7201  C CG1 . VAL C 1 107 ? 87.389  130.036 100.779 1.00 54.47 ? 107 VAL C CG1 1 
ATOM   7202  C CG2 . VAL C 1 107 ? 89.635  129.718 101.753 1.00 54.47 ? 107 VAL C CG2 1 
ATOM   7203  N N   . ASN C 1 108 ? 87.728  129.195 97.541  1.00 62.39 ? 108 ASN C N   1 
ATOM   7204  C CA  . ASN C 1 108 ? 86.824  129.485 96.443  1.00 62.39 ? 108 ASN C CA  1 
ATOM   7205  C C   . ASN C 1 108 ? 85.387  129.297 96.886  1.00 62.39 ? 108 ASN C C   1 
ATOM   7206  O O   . ASN C 1 108 ? 85.075  128.379 97.653  1.00 62.39 ? 108 ASN C O   1 
ATOM   7207  C CB  . ASN C 1 108 ? 87.089  128.578 95.253  1.00 62.39 ? 108 ASN C CB  1 
ATOM   7208  C CG  . ASN C 1 108 ? 85.984  128.636 94.232  1.00 62.39 ? 108 ASN C CG  1 
ATOM   7209  O OD1 . ASN C 1 108 ? 85.197  129.579 94.196  1.00 62.39 ? 108 ASN C OD1 1 
ATOM   7210  N ND2 . ASN C 1 108 ? 85.890  127.601 93.420  1.00 62.39 ? 108 ASN C ND2 1 
ATOM   7211  N N   . TYR C 1 109 ? 84.517  130.146 96.343  1.00 67.21 ? 109 TYR C N   1 
ATOM   7212  C CA  . TYR C 1 109 ? 83.103  130.190 96.684  1.00 67.21 ? 109 TYR C CA  1 
ATOM   7213  C C   . TYR C 1 109 ? 82.276  129.901 95.444  1.00 67.21 ? 109 TYR C C   1 
ATOM   7214  O O   . TYR C 1 109 ? 82.546  130.452 94.373  1.00 67.21 ? 109 TYR C O   1 
ATOM   7215  C CB  . TYR C 1 109 ? 82.718  131.558 97.261  1.00 67.21 ? 109 TYR C CB  1 
ATOM   7216  C CG  . TYR C 1 109 ? 83.621  132.024 98.374  1.00 67.21 ? 109 TYR C CG  1 
ATOM   7217  C CD1 . TYR C 1 109 ? 84.828  132.649 98.104  1.00 67.21 ? 109 TYR C CD1 1 
ATOM   7218  C CD2 . TYR C 1 109 ? 83.274  131.825 99.694  1.00 67.21 ? 109 TYR C CD2 1 
ATOM   7219  C CE1 . TYR C 1 109 ? 85.654  133.060 99.122  1.00 67.21 ? 109 TYR C CE1 1 
ATOM   7220  C CE2 . TYR C 1 109 ? 84.090  132.240 100.714 1.00 67.21 ? 109 TYR C CE2 1 
ATOM   7221  C CZ  . TYR C 1 109 ? 85.277  132.851 100.426 1.00 67.21 ? 109 TYR C CZ  1 
ATOM   7222  O OH  . TYR C 1 109 ? 86.085  133.255 101.457 1.00 67.21 ? 109 TYR C OH  1 
ATOM   7223  N N   . GLN C 1 110 ? 81.275  129.038 95.588  1.00 73.27 ? 110 GLN C N   1 
ATOM   7224  C CA  . GLN C 1 110 ? 80.296  128.816 94.539  1.00 73.27 ? 110 GLN C CA  1 
ATOM   7225  C C   . GLN C 1 110 ? 78.928  128.719 95.189  1.00 73.27 ? 110 GLN C C   1 
ATOM   7226  O O   . GLN C 1 110 ? 78.807  128.623 96.414  1.00 73.27 ? 110 GLN C O   1 
ATOM   7227  C CB  . GLN C 1 110 ? 80.611  127.557 93.729  1.00 73.27 ? 110 GLN C CB  1 
ATOM   7228  C CG  . GLN C 1 110 ? 82.039  127.443 93.259  1.00 73.27 ? 110 GLN C CG  1 
ATOM   7229  C CD  . GLN C 1 110 ? 82.421  126.019 92.957  1.00 73.27 ? 110 GLN C CD  1 
ATOM   7230  O OE1 . GLN C 1 110 ? 81.928  125.421 92.004  1.00 73.27 ? 110 GLN C OE1 1 
ATOM   7231  N NE2 . GLN C 1 110 ? 83.297  125.458 93.780  1.00 73.27 ? 110 GLN C NE2 1 
ATOM   7232  N N   . ALA C 1 111 ? 77.896  128.702 94.354  1.00 76.71 ? 111 ALA C N   1 
ATOM   7233  C CA  . ALA C 1 111 ? 76.524  128.766 94.832  1.00 76.71 ? 111 ALA C CA  1 
ATOM   7234  C C   . ALA C 1 111 ? 76.180  127.559 95.696  1.00 76.71 ? 111 ALA C C   1 
ATOM   7235  O O   . ALA C 1 111 ? 76.931  126.584 95.784  1.00 76.71 ? 111 ALA C O   1 
ATOM   7236  C CB  . ALA C 1 111 ? 75.554  128.855 93.655  1.00 76.71 ? 111 ALA C CB  1 
ATOM   7237  N N   . GLY C 1 112 ? 75.015  127.635 96.332  1.00 80.36 ? 112 GLY C N   1 
ATOM   7238  C CA  . GLY C 1 112 ? 74.599  126.597 97.254  1.00 80.36 ? 112 GLY C CA  1 
ATOM   7239  C C   . GLY C 1 112 ? 75.511  126.485 98.453  1.00 80.36 ? 112 GLY C C   1 
ATOM   7240  O O   . GLY C 1 112 ? 75.574  125.423 99.085  1.00 80.36 ? 112 GLY C O   1 
ATOM   7241  N N   . GLU C 1 113 ? 76.217  127.566 98.783  1.00 80.70 ? 113 GLU C N   1 
ATOM   7242  C CA  . GLU C 1 113 ? 77.209  127.571 99.854  1.00 80.70 ? 113 GLU C CA  1 
ATOM   7243  C C   . GLU C 1 113 ? 78.202  126.427 99.682  1.00 80.70 ? 113 GLU C C   1 
ATOM   7244  O O   . GLU C 1 113 ? 78.389  125.596 100.572 1.00 80.70 ? 113 GLU C O   1 
ATOM   7245  C CB  . GLU C 1 113 ? 76.544  127.523 101.228 1.00 80.70 ? 113 GLU C CB  1 
ATOM   7246  C CG  . GLU C 1 113 ? 75.813  128.797 101.593 1.00 80.70 ? 113 GLU C CG  1 
ATOM   7247  C CD  . GLU C 1 113 ? 74.654  128.544 102.528 1.00 80.70 ? 113 GLU C CD  1 
ATOM   7248  O OE1 . GLU C 1 113 ? 74.352  127.360 102.788 1.00 80.70 ? 113 GLU C OE1 1 
ATOM   7249  O OE2 . GLU C 1 113 ? 74.037  129.524 102.990 1.00 80.70 ? 113 GLU C OE2 1 
ATOM   7250  N N   . SER C 1 114 ? 78.840  126.377 98.515  1.00 74.29 ? 114 SER C N   1 
ATOM   7251  C CA  . SER C 1 114 ? 79.850  125.362 98.227  1.00 74.29 ? 114 SER C CA  1 
ATOM   7252  C C   . SER C 1 114 ? 81.208  126.050 98.159  1.00 74.29 ? 114 SER C C   1 
ATOM   7253  O O   . SER C 1 114 ? 81.620  126.555 97.113  1.00 74.29 ? 114 SER C O   1 
ATOM   7254  C CB  . SER C 1 114 ? 79.528  124.619 96.937  1.00 74.29 ? 114 SER C CB  1 
ATOM   7255  O OG  . SER C 1 114 ? 80.635  123.849 96.519  1.00 74.29 ? 114 SER C OG  1 
ATOM   7256  N N   . SER C 1 115 ? 81.889  126.088 99.293  1.00 62.09 ? 115 SER C N   1 
ATOM   7257  C CA  . SER C 1 115 ? 83.195  126.711 99.410  1.00 62.09 ? 115 SER C CA  1 
ATOM   7258  C C   . SER C 1 115 ? 84.233  125.639 99.683  1.00 62.09 ? 115 SER C C   1 
ATOM   7259  O O   . SER C 1 115 ? 84.004  124.733 100.485 1.00 62.09 ? 115 SER C O   1 
ATOM   7260  C CB  . SER C 1 115 ? 83.200  127.737 100.533 1.00 62.09 ? 115 SER C CB  1 
ATOM   7261  O OG  . SER C 1 115 ? 82.963  127.100 101.770 1.00 62.09 ? 115 SER C OG  1 
ATOM   7262  N N   . MET C 1 116 ? 85.371  125.737 99.018  1.00 53.60 ? 116 MET C N   1 
ATOM   7263  C CA  . MET C 1 116 ? 86.422  124.758 99.231  1.00 53.60 ? 116 MET C CA  1 
ATOM   7264  C C   . MET C 1 116 ? 87.783  125.433 99.256  1.00 53.60 ? 116 MET C C   1 
ATOM   7265  O O   . MET C 1 116 ? 87.976  126.516 98.702  1.00 53.60 ? 116 MET C O   1 
ATOM   7266  C CB  . MET C 1 116 ? 86.397  123.667 98.173  1.00 53.60 ? 116 MET C CB  1 
ATOM   7267  C CG  . MET C 1 116 ? 86.569  124.163 96.774  1.00 53.60 ? 116 MET C CG  1 
ATOM   7268  S SD  . MET C 1 116 ? 87.217  122.871 95.690  1.00 53.60 ? 116 MET C SD  1 
ATOM   7269  C CE  . MET C 1 116 ? 88.853  122.637 96.380  1.00 53.60 ? 116 MET C CE  1 
ATOM   7270  N N   . PHE C 1 117 ? 88.724  124.776 99.918  1.00 43.64 ? 117 PHE C N   1 
ATOM   7271  C CA  . PHE C 1 117 ? 90.052  125.317 100.147 1.00 43.64 ? 117 PHE C CA  1 
ATOM   7272  C C   . PHE C 1 117 ? 91.023  124.708 99.156  1.00 43.64 ? 117 PHE C C   1 
ATOM   7273  O O   . PHE C 1 117 ? 90.942  123.518 98.826  1.00 43.64 ? 117 PHE C O   1 
ATOM   7274  C CB  . PHE C 1 117 ? 90.515  125.038 101.576 1.00 43.64 ? 117 PHE C CB  1 
ATOM   7275  C CG  . PHE C 1 117 ? 91.873  125.596 101.914 1.00 43.64 ? 117 PHE C CG  1 
ATOM   7276  C CD1 . PHE C 1 117 ? 92.014  126.895 102.350 1.00 43.64 ? 117 PHE C CD1 1 
ATOM   7277  C CD2 . PHE C 1 117 ? 93.003  124.806 101.839 1.00 43.64 ? 117 PHE C CD2 1 
ATOM   7278  C CE1 . PHE C 1 117 ? 93.251  127.394 102.672 1.00 43.64 ? 117 PHE C CE1 1 
ATOM   7279  C CE2 . PHE C 1 117 ? 94.240  125.308 102.168 1.00 43.64 ? 117 PHE C CE2 1 
ATOM   7280  C CZ  . PHE C 1 117 ? 94.360  126.596 102.582 1.00 43.64 ? 117 PHE C CZ  1 
ATOM   7281  N N   . ARG C 1 118 ? 91.937  125.528 98.687  1.00 49.02 ? 118 ARG C N   1 
ATOM   7282  C CA  . ARG C 1 118 ? 92.915  125.140 97.699  1.00 49.02 ? 118 ARG C CA  1 
ATOM   7283  C C   . ARG C 1 118 ? 94.099  126.073 97.861  1.00 49.02 ? 118 ARG C C   1 
ATOM   7284  O O   . ARG C 1 118 ? 93.988  127.163 98.422  1.00 49.02 ? 118 ARG C O   1 
ATOM   7285  C CB  . ARG C 1 118 ? 92.322  125.186 96.283  1.00 49.02 ? 118 ARG C CB  1 
ATOM   7286  C CG  . ARG C 1 118 ? 91.798  126.538 95.890  1.00 49.02 ? 118 ARG C CG  1 
ATOM   7287  C CD  . ARG C 1 118 ? 91.174  126.611 94.509  1.00 49.02 ? 118 ARG C CD  1 
ATOM   7288  N NE  . ARG C 1 118 ? 89.740  126.337 94.483  1.00 49.02 ? 118 ARG C NE  1 
ATOM   7289  C CZ  . ARG C 1 118 ? 89.186  125.300 93.865  1.00 49.02 ? 118 ARG C CZ  1 
ATOM   7290  N NH1 . ARG C 1 118 ? 89.943  124.422 93.229  1.00 49.02 ? 118 ARG C NH1 1 
ATOM   7291  N NH2 . ARG C 1 118 ? 87.872  125.140 93.879  1.00 49.02 ? 118 ARG C NH2 1 
ATOM   7292  N N   . PHE C 1 119 ? 95.280  125.582 97.575  1.00 40.22 ? 119 PHE C N   1 
ATOM   7293  C CA  . PHE C 1 119 ? 96.433  126.363 97.740  1.00 40.22 ? 119 PHE C CA  1 
ATOM   7294  C C   . PHE C 1 119 ? 97.388  126.123 96.656  1.00 40.22 ? 119 PHE C C   1 
ATOM   7295  O O   . PHE C 1 119 ? 97.370  125.103 96.075  1.00 40.22 ? 119 PHE C O   1 
ATOM   7296  C CB  . PHE C 1 119 ? 96.989  126.246 99.114  1.00 40.22 ? 119 PHE C CB  1 
ATOM   7297  C CG  . PHE C 1 119 ? 98.161  125.368 99.275  1.00 40.22 ? 119 PHE C CG  1 
ATOM   7298  C CD1 . PHE C 1 119 ? 99.427  125.897 99.243  1.00 40.22 ? 119 PHE C CD1 1 
ATOM   7299  C CD2 . PHE C 1 119 ? 97.995  124.049 99.595  1.00 40.22 ? 119 PHE C CD2 1 
ATOM   7300  C CE1 . PHE C 1 119 ? 100.520 125.103 99.436  1.00 40.22 ? 119 PHE C CE1 1 
ATOM   7301  C CE2 . PHE C 1 119 ? 99.081  123.248 99.785  1.00 40.22 ? 119 PHE C CE2 1 
ATOM   7302  C CZ  . PHE C 1 119 ? 100.345 123.776 99.704  1.00 40.22 ? 119 PHE C CZ  1 
ATOM   7303  N N   . THR C 1 120 ? 98.149  127.131 96.298  1.00 40.07 ? 120 THR C N   1 
ATOM   7304  C CA  . THR C 1 120 ? 99.100  127.081 95.200  1.00 40.07 ? 120 THR C CA  1 
ATOM   7305  C C   . THR C 1 120 ? 100.502 127.289 95.734  1.00 40.07 ? 120 THR C C   1 
ATOM   7306  O O   . THR C 1 120 ? 100.722 128.148 96.587  1.00 40.07 ? 120 THR C O   1 
ATOM   7307  C CB  . THR C 1 120 ? 98.788  128.146 94.154  1.00 40.07 ? 120 THR C CB  1 
ATOM   7308  O OG1 . THR C 1 120 ? 97.455  127.962 93.675  1.00 40.07 ? 120 THR C OG1 1 
ATOM   7309  C CG2 . THR C 1 120 ? 99.739  128.039 92.989  1.00 40.07 ? 120 THR C CG2 1 
ATOM   7310  N N   . ILE C 1 121 ? 101.447 126.519 95.222  1.00 38.89 ? 121 ILE C N   1 
ATOM   7311  C CA  . ILE C 1 121 ? 102.838 126.680 95.593  1.00 38.89 ? 121 ILE C CA  1 
ATOM   7312  C C   . ILE C 1 121 ? 103.701 126.384 94.379  1.00 38.89 ? 121 ILE C C   1 
ATOM   7313  O O   . ILE C 1 121 ? 103.398 125.488 93.585  1.00 38.89 ? 121 ILE C O   1 
ATOM   7314  C CB  . ILE C 1 121 ? 103.202 125.771 96.781  1.00 38.89 ? 121 ILE C CB  1 
ATOM   7315  C CG1 . ILE C 1 121 ? 104.701 125.808 97.050  1.00 38.89 ? 121 ILE C CG1 1 
ATOM   7316  C CG2 . ILE C 1 121 ? 102.749 124.362 96.537  1.00 38.89 ? 121 ILE C CG2 1 
ATOM   7317  C CD1 . ILE C 1 121 ? 105.107 125.031 98.255  1.00 38.89 ? 121 ILE C CD1 1 
ATOM   7318  N N   . GLU C 1 122 ? 104.747 127.159 94.217  1.00 40.81 ? 122 GLU C N   1 
ATOM   7319  C CA  . GLU C 1 122 ? 105.806 126.791 93.302  1.00 40.81 ? 122 GLU C CA  1 
ATOM   7320  C C   . GLU C 1 122 ? 106.787 125.968 94.122  1.00 40.81 ? 122 GLU C C   1 
ATOM   7321  O O   . GLU C 1 122 ? 107.569 126.537 94.890  1.00 40.81 ? 122 GLU C O   1 
ATOM   7322  C CB  . GLU C 1 122 ? 106.452 128.037 92.695  1.00 40.81 ? 122 GLU C CB  1 
ATOM   7323  C CG  . GLU C 1 122 ? 107.269 127.809 91.438  1.00 40.81 ? 122 GLU C CG  1 
ATOM   7324  C CD  . GLU C 1 122 ? 108.766 127.846 91.677  1.00 40.81 ? 122 GLU C CD  1 
ATOM   7325  O OE1 . GLU C 1 122 ? 109.212 128.594 92.569  1.00 40.81 ? 122 GLU C OE1 1 
ATOM   7326  O OE2 . GLU C 1 122 ? 109.504 127.134 90.964  1.00 40.81 ? 122 GLU C OE2 1 
ATOM   7327  N N   . PRO C 1 123 ? 106.749 124.632 94.029  1.00 39.57 ? 123 PRO C N   1 
ATOM   7328  C CA  . PRO C 1 123 ? 107.619 123.813 94.875  1.00 39.57 ? 123 PRO C CA  1 
ATOM   7329  C C   . PRO C 1 123 ? 109.066 124.221 94.757  1.00 39.57 ? 123 PRO C C   1 
ATOM   7330  O O   . PRO C 1 123 ? 109.631 124.205 93.664  1.00 39.57 ? 123 PRO C O   1 
ATOM   7331  C CB  . PRO C 1 123 ? 107.395 122.399 94.338  1.00 39.57 ? 123 PRO C CB  1 
ATOM   7332  C CG  . PRO C 1 123 ? 106.068 122.441 93.739  1.00 39.57 ? 123 PRO C CG  1 
ATOM   7333  C CD  . PRO C 1 123 ? 105.915 123.796 93.153  1.00 39.57 ? 123 PRO C CD  1 
ATOM   7334  N N   . VAL C 1 124 ? 109.663 124.609 95.873  1.00 37.96 ? 124 VAL C N   1 
ATOM   7335  C CA  . VAL C 1 124 ? 111.040 125.068 95.916  1.00 37.96 ? 124 VAL C CA  1 
ATOM   7336  C C   . VAL C 1 124 ? 111.829 124.097 96.772  1.00 37.96 ? 124 VAL C C   1 
ATOM   7337  O O   . VAL C 1 124 ? 111.435 123.798 97.901  1.00 37.96 ? 124 VAL C O   1 
ATOM   7338  C CB  . VAL C 1 124 ? 111.139 126.495 96.475  1.00 37.96 ? 124 VAL C CB  1 
ATOM   7339  C CG1 . VAL C 1 124 ? 112.567 126.864 96.711  1.00 37.96 ? 124 VAL C CG1 1 
ATOM   7340  C CG2 . VAL C 1 124 ? 110.523 127.455 95.520  1.00 37.96 ? 124 VAL C CG2 1 
ATOM   7341  N N   . GLY C 1 125 ? 112.925 123.594 96.235  1.00 38.10 ? 125 GLY C N   1 
ATOM   7342  C CA  . GLY C 1 125 ? 113.799 122.757 97.008  1.00 38.10 ? 125 GLY C CA  1 
ATOM   7343  C C   . GLY C 1 125 ? 114.477 123.572 98.078  1.00 38.10 ? 125 GLY C C   1 
ATOM   7344  O O   . GLY C 1 125 ? 114.600 124.791 97.968  1.00 38.10 ? 125 GLY C O   1 
ATOM   7345  N N   . PRO C 1 126 ? 114.933 122.918 99.143  1.00 38.46 ? 126 PRO C N   1 
ATOM   7346  C CA  . PRO C 1 126 ? 115.644 123.654 100.192 1.00 38.46 ? 126 PRO C CA  1 
ATOM   7347  C C   . PRO C 1 126 ? 116.882 124.353 99.690  1.00 38.46 ? 126 PRO C C   1 
ATOM   7348  O O   . PRO C 1 126 ? 117.408 125.224 100.388 1.00 38.46 ? 126 PRO C O   1 
ATOM   7349  C CB  . PRO C 1 126 ? 115.992 122.564 101.208 1.00 38.46 ? 126 PRO C CB  1 
ATOM   7350  C CG  . PRO C 1 126 ? 115.968 121.316 100.437 1.00 38.46 ? 126 PRO C CG  1 
ATOM   7351  C CD  . PRO C 1 126 ? 114.885 121.480 99.429  1.00 38.46 ? 126 PRO C CD  1 
ATOM   7352  N N   . HIS C 1 127 ? 117.365 124.003 98.499  1.00 43.81 ? 127 HIS C N   1 
ATOM   7353  C CA  . HIS C 1 127 ? 118.531 124.649 97.913  1.00 43.81 ? 127 HIS C CA  1 
ATOM   7354  C C   . HIS C 1 127 ? 118.279 125.079 96.476  1.00 43.81 ? 127 HIS C C   1 
ATOM   7355  O O   . HIS C 1 127 ? 119.228 125.225 95.709  1.00 43.81 ? 127 HIS C O   1 
ATOM   7356  C CB  . HIS C 1 127 ? 119.744 123.726 97.991  1.00 43.81 ? 127 HIS C CB  1 
ATOM   7357  C CG  . HIS C 1 127 ? 119.863 123.013 99.298  1.00 43.81 ? 127 HIS C CG  1 
ATOM   7358  N ND1 . HIS C 1 127 ? 120.037 123.677 100.491 1.00 43.81 ? 127 HIS C ND1 1 
ATOM   7359  C CD2 . HIS C 1 127 ? 119.823 121.696 99.604  1.00 43.81 ? 127 HIS C CD2 1 
ATOM   7360  C CE1 . HIS C 1 127 ? 120.100 122.801 101.476 1.00 43.81 ? 127 HIS C CE1 1 
ATOM   7361  N NE2 . HIS C 1 127 ? 119.973 121.591 100.965 1.00 43.81 ? 127 HIS C NE2 1 
ATOM   7362  N N   . ALA C 1 128 ? 117.023 125.282 96.100  1.00 43.38 ? 128 ALA C N   1 
ATOM   7363  C CA  . ALA C 1 128 ? 116.699 125.702 94.749  1.00 43.38 ? 128 ALA C CA  1 
ATOM   7364  C C   . ALA C 1 128 ? 117.210 127.109 94.491  1.00 43.38 ? 128 ALA C C   1 
ATOM   7365  O O   . ALA C 1 128 ? 117.150 127.981 95.354  1.00 43.38 ? 128 ALA C O   1 
ATOM   7366  C CB  . ALA C 1 128 ? 115.196 125.654 94.525  1.00 43.38 ? 128 ALA C CB  1 
ATOM   7367  N N   . GLY C 1 129 ? 117.704 127.332 93.282  1.00 44.90 ? 129 GLY C N   1 
ATOM   7368  C CA  . GLY C 1 129 ? 118.323 128.597 92.976  1.00 44.90 ? 129 GLY C CA  1 
ATOM   7369  C C   . GLY C 1 129 ? 119.752 128.717 93.431  1.00 44.90 ? 129 GLY C C   1 
ATOM   7370  O O   . GLY C 1 129 ? 120.304 129.820 93.403  1.00 44.90 ? 129 GLY C O   1 
ATOM   7371  N N   . THR C 1 130 ? 120.361 127.623 93.855  1.00 46.96 ? 130 THR C N   1 
ATOM   7372  C CA  . THR C 1 130 ? 121.760 127.550 94.230  1.00 46.96 ? 130 THR C CA  1 
ATOM   7373  C C   . THR C 1 130 ? 122.443 126.507 93.360  1.00 46.96 ? 130 THR C C   1 
ATOM   7374  O O   . THR C 1 130 ? 121.774 125.677 92.740  1.00 46.96 ? 130 THR C O   1 
ATOM   7375  C CB  . THR C 1 130 ? 121.894 127.189 95.713  1.00 46.96 ? 130 THR C CB  1 
ATOM   7376  O OG1 . THR C 1 130 ? 121.092 126.040 95.994  1.00 46.96 ? 130 THR C OG1 1 
ATOM   7377  C CG2 . THR C 1 130 ? 121.422 128.337 96.572  1.00 46.96 ? 130 THR C CG2 1 
ATOM   7378  N N   . PRO C 1 131 ? 123.778 126.521 93.279  1.00 50.86 ? 131 PRO C N   1 
ATOM   7379  C CA  . PRO C 1 131 ? 124.451 125.630 92.322  1.00 50.86 ? 131 PRO C CA  1 
ATOM   7380  C C   . PRO C 1 131 ? 124.204 124.159 92.563  1.00 50.86 ? 131 PRO C C   1 
ATOM   7381  O O   . PRO C 1 131 ? 124.619 123.341 91.735  1.00 50.86 ? 131 PRO C O   1 
ATOM   7382  C CB  . PRO C 1 131 ? 125.931 125.981 92.503  1.00 50.86 ? 131 PRO C CB  1 
ATOM   7383  C CG  . PRO C 1 131 ? 125.921 127.356 93.027  1.00 50.86 ? 131 PRO C CG  1 
ATOM   7384  C CD  . PRO C 1 131 ? 124.737 127.421 93.933  1.00 50.86 ? 131 PRO C CD  1 
ATOM   7385  N N   . ALA C 1 132 ? 123.556 123.786 93.666  1.00 49.05 ? 132 ALA C N   1 
ATOM   7386  C CA  . ALA C 1 132 ? 123.174 122.394 93.867  1.00 49.05 ? 132 ALA C CA  1 
ATOM   7387  C C   . ALA C 1 132 ? 121.832 122.071 93.228  1.00 49.05 ? 132 ALA C C   1 
ATOM   7388  O O   . ALA C 1 132 ? 121.568 120.906 92.919  1.00 49.05 ? 132 ALA C O   1 
ATOM   7389  C CB  . ALA C 1 132 ? 123.131 122.067 95.356  1.00 49.05 ? 132 ALA C CB  1 
ATOM   7390  N N   . ASP C 1 133 ? 120.975 123.070 93.029  1.00 47.31 ? 133 ASP C N   1 
ATOM   7391  C CA  . ASP C 1 133 ? 119.678 122.883 92.379  1.00 47.31 ? 133 ASP C CA  1 
ATOM   7392  C C   . ASP C 1 133 ? 119.324 124.143 91.608  1.00 47.31 ? 133 ASP C C   1 
ATOM   7393  O O   . ASP C 1 133 ? 118.377 124.858 91.945  1.00 47.31 ? 133 ASP C O   1 
ATOM   7394  C CB  . ASP C 1 133 ? 118.600 122.546 93.409  1.00 47.31 ? 133 ASP C CB  1 
ATOM   7395  C CG  . ASP C 1 133 ? 117.335 122.013 92.777  1.00 47.31 ? 133 ASP C CG  1 
ATOM   7396  O OD1 . ASP C 1 133 ? 117.247 121.996 91.535  1.00 47.31 ? 133 ASP C OD1 1 
ATOM   7397  O OD2 . ASP C 1 133 ? 116.424 121.604 93.526  1.00 47.31 ? 133 ASP C OD2 1 
ATOM   7398  N N   . PRO C 1 134 ? 120.063 124.436 90.533  1.00 46.32 ? 134 PRO C N   1 
ATOM   7399  C CA  . PRO C 1 134 ? 119.878 125.721 89.850  1.00 46.32 ? 134 PRO C CA  1 
ATOM   7400  C C   . PRO C 1 134 ? 118.539 125.880 89.162  1.00 46.32 ? 134 PRO C C   1 
ATOM   7401  O O   . PRO C 1 134 ? 118.162 127.015 88.857  1.00 46.32 ? 134 PRO C O   1 
ATOM   7402  C CB  . PRO C 1 134 ? 121.023 125.741 88.834  1.00 46.32 ? 134 PRO C CB  1 
ATOM   7403  C CG  . PRO C 1 134 ? 121.377 124.328 88.638  1.00 46.32 ? 134 PRO C CG  1 
ATOM   7404  C CD  . PRO C 1 134 ? 121.162 123.657 89.946  1.00 46.32 ? 134 PRO C CD  1 
ATOM   7405  N N   . VAL C 1 135 ? 117.804 124.804 88.900  1.00 46.86 ? 135 VAL C N   1 
ATOM   7406  C CA  . VAL C 1 135 ? 116.549 124.915 88.174  1.00 46.86 ? 135 VAL C CA  1 
ATOM   7407  C C   . VAL C 1 135 ? 115.378 124.338 88.948  1.00 46.86 ? 135 VAL C C   1 
ATOM   7408  O O   . VAL C 1 135 ? 114.290 124.203 88.395  1.00 46.86 ? 135 VAL C O   1 
ATOM   7409  C CB  . VAL C 1 135 ? 116.646 124.261 86.786  1.00 46.86 ? 135 VAL C CB  1 
ATOM   7410  C CG1 . VAL C 1 135 ? 117.414 125.157 85.851  1.00 46.86 ? 135 VAL C CG1 1 
ATOM   7411  C CG2 . VAL C 1 135 ? 117.319 122.921 86.899  1.00 46.86 ? 135 VAL C CG2 1 
ATOM   7412  N N   . ASN C 1 136 ? 115.579 123.984 90.215  1.00 43.75 ? 136 ASN C N   1 
ATOM   7413  C CA  . ASN C 1 136 ? 114.494 123.523 91.070  1.00 43.75 ? 136 ASN C CA  1 
ATOM   7414  C C   . ASN C 1 136 ? 113.769 122.338 90.431  1.00 43.75 ? 136 ASN C C   1 
ATOM   7415  O O   . ASN C 1 136 ? 112.565 122.363 90.182  1.00 43.75 ? 136 ASN C O   1 
ATOM   7416  C CB  . ASN C 1 136 ? 113.534 124.677 91.363  1.00 43.75 ? 136 ASN C CB  1 
ATOM   7417  C CG  . ASN C 1 136 ? 112.592 124.379 92.486  1.00 43.75 ? 136 ASN C CG  1 
ATOM   7418  O OD1 . ASN C 1 136 ? 112.948 123.709 93.445  1.00 43.75 ? 136 ASN C OD1 1 
ATOM   7419  N ND2 . ASN C 1 136 ? 111.377 124.881 92.379  1.00 43.75 ? 136 ASN C ND2 1 
ATOM   7420  N N   . GLU C 1 137 ? 114.535 121.284 90.169  1.00 48.20 ? 137 GLU C N   1 
ATOM   7421  C CA  . GLU C 1 137 ? 114.033 120.160 89.390  1.00 48.20 ? 137 GLU C CA  1 
ATOM   7422  C C   . GLU C 1 137 ? 113.277 119.131 90.221  1.00 48.20 ? 137 GLU C C   1 
ATOM   7423  O O   . GLU C 1 137 ? 112.232 118.638 89.790  1.00 48.20 ? 137 GLU C O   1 
ATOM   7424  C CB  . GLU C 1 137 ? 115.192 119.482 88.670  1.00 48.20 ? 137 GLU C CB  1 
ATOM   7425  C CG  . GLU C 1 137 ? 116.435 119.386 89.515  1.00 48.20 ? 137 GLU C CG  1 
ATOM   7426  C CD  . GLU C 1 137 ? 117.439 118.408 88.955  1.00 48.20 ? 137 GLU C CD  1 
ATOM   7427  O OE1 . GLU C 1 137 ? 117.091 117.669 88.013  1.00 48.20 ? 137 GLU C OE1 1 
ATOM   7428  O OE2 . GLU C 1 137 ? 118.578 118.377 89.458  1.00 48.20 ? 137 GLU C OE2 1 
ATOM   7429  N N   . LEU C 1 138 ? 113.783 118.790 91.404  1.00 44.36 ? 138 LEU C N   1 
ATOM   7430  C CA  . LEU C 1 138 ? 113.239 117.656 92.138  1.00 44.36 ? 138 LEU C CA  1 
ATOM   7431  C C   . LEU C 1 138 ? 111.960 118.002 92.876  1.00 44.36 ? 138 LEU C C   1 
ATOM   7432  O O   . LEU C 1 138 ? 111.051 117.176 92.941  1.00 44.36 ? 138 LEU C O   1 
ATOM   7433  C CB  . LEU C 1 138 ? 114.268 117.126 93.128  1.00 44.36 ? 138 LEU C CB  1 
ATOM   7434  C CG  . LEU C 1 138 ? 115.462 116.403 92.528  1.00 44.36 ? 138 LEU C CG  1 
ATOM   7435  C CD1 . LEU C 1 138 ? 116.241 115.725 93.619  1.00 44.36 ? 138 LEU C CD1 1 
ATOM   7436  C CD2 . LEU C 1 138 ? 114.998 115.396 91.510  1.00 44.36 ? 138 LEU C CD2 1 
ATOM   7437  N N   . ALA C 1 139 ? 111.873 119.214 93.424  1.00 42.33 ? 139 ALA C N   1 
ATOM   7438  C CA  . ALA C 1 139 ? 110.837 119.536 94.400  1.00 42.33 ? 139 ALA C CA  1 
ATOM   7439  C C   . ALA C 1 139 ? 109.457 119.101 93.942  1.00 42.33 ? 139 ALA C C   1 
ATOM   7440  O O   . ALA C 1 139 ? 108.703 118.505 94.715  1.00 42.33 ? 139 ALA C O   1 
ATOM   7441  C CB  . ALA C 1 139 ? 110.848 121.030 94.692  1.00 42.33 ? 139 ALA C CB  1 
ATOM   7442  N N   . ALA C 1 140 ? 109.114 119.369 92.685  1.00 42.38 ? 140 ALA C N   1 
ATOM   7443  C CA  . ALA C 1 140 ? 107.787 119.009 92.199  1.00 42.38 ? 140 ALA C CA  1 
ATOM   7444  C C   . ALA C 1 140 ? 107.593 117.500 92.181  1.00 42.38 ? 140 ALA C C   1 
ATOM   7445  O O   . ALA C 1 140 ? 106.530 116.998 92.559  1.00 42.38 ? 140 ALA C O   1 
ATOM   7446  C CB  . ALA C 1 140 ? 107.567 119.593 90.810  1.00 42.38 ? 140 ALA C CB  1 
ATOM   7447  N N   . LYS C 1 141 ? 108.620 116.759 91.768  1.00 44.26 ? 141 LYS C N   1 
ATOM   7448  C CA  . LYS C 1 141 ? 108.505 115.310 91.704  1.00 44.26 ? 141 LYS C CA  1 
ATOM   7449  C C   . LYS C 1 141 ? 108.486 114.690 93.092  1.00 44.26 ? 141 LYS C C   1 
ATOM   7450  O O   . LYS C 1 141 ? 107.760 113.725 93.331  1.00 44.26 ? 141 LYS C O   1 
ATOM   7451  C CB  . LYS C 1 141 ? 109.642 114.738 90.875  1.00 44.26 ? 141 LYS C CB  1 
ATOM   7452  C CG  . LYS C 1 141 ? 109.519 115.050 89.414  1.00 44.26 ? 141 LYS C CG  1 
ATOM   7453  C CD  . LYS C 1 141 ? 110.794 114.716 88.697  1.00 44.26 ? 141 LYS C CD  1 
ATOM   7454  C CE  . LYS C 1 141 ? 110.666 114.963 87.220  1.00 44.26 ? 141 LYS C CE  1 
ATOM   7455  N NZ  . LYS C 1 141 ? 111.985 114.813 86.561  1.00 44.26 ? 141 LYS C NZ  1 
ATOM   7456  N N   . GLN C 1 142 ? 109.286 115.219 94.016  1.00 43.02 ? 142 GLN C N   1 
ATOM   7457  C CA  . GLN C 1 142 ? 109.220 114.758 95.396  1.00 43.02 ? 142 GLN C CA  1 
ATOM   7458  C C   . GLN C 1 142 ? 107.845 115.005 95.987  1.00 43.02 ? 142 GLN C C   1 
ATOM   7459  O O   . GLN C 1 142 ? 107.305 114.151 96.693  1.00 43.02 ? 142 GLN C O   1 
ATOM   7460  C CB  . GLN C 1 142 ? 110.282 115.451 96.236  1.00 43.02 ? 142 GLN C CB  1 
ATOM   7461  C CG  . GLN C 1 142 ? 111.678 115.018 95.929  1.00 43.02 ? 142 GLN C CG  1 
ATOM   7462  C CD  . GLN C 1 142 ? 112.684 115.766 96.746  1.00 43.02 ? 142 GLN C CD  1 
ATOM   7463  O OE1 . GLN C 1 142 ? 112.348 116.729 97.421  1.00 43.02 ? 142 GLN C OE1 1 
ATOM   7464  N NE2 . GLN C 1 142 ? 113.927 115.331 96.697  1.00 43.02 ? 142 GLN C NE2 1 
ATOM   7465  N N   . LEU C 1 143 ? 107.263 116.168 95.714  1.00 43.96 ? 143 LEU C N   1 
ATOM   7466  C CA  . LEU C 1 143 ? 105.914 116.445 96.183  1.00 43.96 ? 143 LEU C CA  1 
ATOM   7467  C C   . LEU C 1 143 ? 104.919 115.462 95.585  1.00 43.96 ? 143 LEU C C   1 
ATOM   7468  O O   . LEU C 1 143 ? 104.072 114.915 96.296  1.00 43.96 ? 143 LEU C O   1 
ATOM   7469  C CB  . LEU C 1 143 ? 105.540 117.882 95.838  1.00 43.96 ? 143 LEU C CB  1 
ATOM   7470  C CG  . LEU C 1 143 ? 104.112 118.332 96.097  1.00 43.96 ? 143 LEU C CG  1 
ATOM   7471  C CD1 . LEU C 1 143 ? 103.789 118.197 97.548  1.00 43.96 ? 143 LEU C CD1 1 
ATOM   7472  C CD2 . LEU C 1 143 ? 103.949 119.759 95.671  1.00 43.96 ? 143 LEU C CD2 1 
ATOM   7473  N N   . MET C 1 144 ? 105.017 115.212 94.276  1.00 48.58 ? 144 MET C N   1 
ATOM   7474  C CA  . MET C 1 144 ? 104.114 114.267 93.621  1.00 48.58 ? 144 MET C CA  1 
ATOM   7475  C C   . MET C 1 144 ? 104.245 112.874 94.217  1.00 48.58 ? 144 MET C C   1 
ATOM   7476  O O   . MET C 1 144 ? 103.246 112.207 94.502  1.00 48.58 ? 144 MET C O   1 
ATOM   7477  C CB  . MET C 1 144 ? 104.407 114.216 92.124  1.00 48.58 ? 144 MET C CB  1 
ATOM   7478  C CG  . MET C 1 144 ? 103.991 115.436 91.346  1.00 48.58 ? 144 MET C CG  1 
ATOM   7479  S SD  . MET C 1 144 ? 103.854 115.091 89.584  1.00 48.58 ? 144 MET C SD  1 
ATOM   7480  C CE  . MET C 1 144 ? 102.633 113.787 89.582  1.00 48.58 ? 144 MET C CE  1 
ATOM   7481  N N   . GLN C 1 145 ? 105.480 112.419 94.402  1.00 46.87 ? 145 GLN C N   1 
ATOM   7482  C CA  . GLN C 1 145 ? 105.734 111.083 94.922  1.00 46.87 ? 145 GLN C CA  1 
ATOM   7483  C C   . GLN C 1 145 ? 105.236 110.936 96.349  1.00 46.87 ? 145 GLN C C   1 
ATOM   7484  O O   . GLN C 1 145 ? 104.552 109.965 96.680  1.00 46.87 ? 145 GLN C O   1 
ATOM   7485  C CB  . GLN C 1 145 ? 107.223 110.789 94.845  1.00 46.87 ? 145 GLN C CB  1 
ATOM   7486  C CG  . GLN C 1 145 ? 107.649 109.621 95.666  1.00 46.87 ? 145 GLN C CG  1 
ATOM   7487  C CD  . GLN C 1 145 ? 109.087 109.275 95.434  1.00 46.87 ? 145 GLN C CD  1 
ATOM   7488  O OE1 . GLN C 1 145 ? 109.727 109.825 94.545  1.00 46.87 ? 145 GLN C OE1 1 
ATOM   7489  N NE2 . GLN C 1 145 ? 109.617 108.370 96.243  1.00 46.87 ? 145 GLN C NE2 1 
ATOM   7490  N N   . ARG C 1 146 ? 105.609 111.871 97.217  1.00 48.87 ? 146 ARG C N   1 
ATOM   7491  C CA  . ARG C 1 146 ? 105.117 111.858 98.585  1.00 48.87 ? 146 ARG C CA  1 
ATOM   7492  C C   . ARG C 1 146 ? 103.603 111.861 98.615  1.00 48.87 ? 146 ARG C C   1 
ATOM   7493  O O   . ARG C 1 146 ? 102.986 111.110 99.376  1.00 48.87 ? 146 ARG C O   1 
ATOM   7494  C CB  . ARG C 1 146 ? 105.677 113.067 99.326  1.00 48.87 ? 146 ARG C CB  1 
ATOM   7495  C CG  . ARG C 1 146 ? 105.434 113.073 100.800 1.00 48.87 ? 146 ARG C CG  1 
ATOM   7496  C CD  . ARG C 1 146 ? 106.259 112.023 101.483 1.00 48.87 ? 146 ARG C CD  1 
ATOM   7497  N NE  . ARG C 1 146 ? 105.421 110.931 101.953 1.00 48.87 ? 146 ARG C NE  1 
ATOM   7498  C CZ  . ARG C 1 146 ? 105.868 109.897 102.651 1.00 48.87 ? 146 ARG C CZ  1 
ATOM   7499  N NH1 . ARG C 1 146 ? 107.151 109.812 102.965 1.00 48.87 ? 146 ARG C NH1 1 
ATOM   7500  N NH2 . ARG C 1 146 ? 105.028 108.949 103.034 1.00 48.87 ? 146 ARG C NH2 1 
ATOM   7501  N N   . LEU C 1 147 ? 102.984 112.675 97.772  1.00 47.43 ? 147 LEU C N   1 
ATOM   7502  C CA  . LEU C 1 147 ? 101.541 112.797 97.801  1.00 47.43 ? 147 LEU C CA  1 
ATOM   7503  C C   . LEU C 1 147 ? 100.869 111.525 97.301  1.00 47.43 ? 147 LEU C C   1 
ATOM   7504  O O   . LEU C 1 147 ? 99.774  111.182 97.755  1.00 47.43 ? 147 LEU C O   1 
ATOM   7505  C CB  . LEU C 1 147 ? 101.136 114.006 96.970  1.00 47.43 ? 147 LEU C CB  1 
ATOM   7506  C CG  . LEU C 1 147 ? 99.746  114.562 97.206  1.00 47.43 ? 147 LEU C CG  1 
ATOM   7507  C CD1 . LEU C 1 147 ? 99.709  115.100 98.602  1.00 47.43 ? 147 LEU C CD1 1 
ATOM   7508  C CD2 . LEU C 1 147 ? 99.470  115.654 96.221  1.00 47.43 ? 147 LEU C CD2 1 
ATOM   7509  N N   . GLY C 1 148 ? 101.505 110.809 96.376  1.00 52.06 ? 148 GLY C N   1 
ATOM   7510  C CA  . GLY C 1 148 ? 100.963 109.527 95.954  1.00 52.06 ? 148 GLY C CA  1 
ATOM   7511  C C   . GLY C 1 148 ? 101.176 108.438 96.987  1.00 52.06 ? 148 GLY C C   1 
ATOM   7512  O O   . GLY C 1 148 ? 100.327 107.565 97.167  1.00 52.06 ? 148 GLY C O   1 
ATOM   7513  N N   . GLN C 1 149 ? 102.318 108.469 97.670  1.00 49.50 ? 149 GLN C N   1 
ATOM   7514  C CA  . GLN C 1 149 ? 102.569 107.525 98.751  1.00 49.50 ? 149 GLN C CA  1 
ATOM   7515  C C   . GLN C 1 149 ? 101.563 107.700 99.878  1.00 49.50 ? 149 GLN C C   1 
ATOM   7516  O O   . GLN C 1 149 ? 101.137 106.720 100.495 1.00 49.50 ? 149 GLN C O   1 
ATOM   7517  C CB  . GLN C 1 149 ? 103.989 107.708 99.273  1.00 49.50 ? 149 GLN C CB  1 
ATOM   7518  C CG  . GLN C 1 149 ? 104.284 106.964 100.543 1.00 49.50 ? 149 GLN C CG  1 
ATOM   7519  C CD  . GLN C 1 149 ? 104.658 105.524 100.296 1.00 49.50 ? 149 GLN C CD  1 
ATOM   7520  O OE1 . GLN C 1 149 ? 104.969 105.136 99.173  1.00 49.50 ? 149 GLN C OE1 1 
ATOM   7521  N NE2 . GLN C 1 149 ? 104.636 104.719 101.351 1.00 49.50 ? 149 GLN C NE2 1 
ATOM   7522  N N   . LEU C 1 150 ? 101.169 108.939 100.163 1.00 49.71 ? 150 LEU C N   1 
ATOM   7523  C CA  . LEU C 1 150 ? 100.169 109.160 101.200 1.00 49.71 ? 150 LEU C CA  1 
ATOM   7524  C C   . LEU C 1 150 ? 98.826  108.577 100.793 1.00 49.71 ? 150 LEU C C   1 
ATOM   7525  O O   . LEU C 1 150 ? 98.199  107.846 101.565 1.00 49.71 ? 150 LEU C O   1 
ATOM   7526  C CB  . LEU C 1 150 ? 100.037 110.649 101.505 1.00 49.71 ? 150 LEU C CB  1 
ATOM   7527  C CG  . LEU C 1 150 ? 101.288 111.302 102.091 1.00 49.71 ? 150 LEU C CG  1 
ATOM   7528  C CD1 . LEU C 1 150 ? 101.007 112.714 102.564 1.00 49.71 ? 150 LEU C CD1 1 
ATOM   7529  C CD2 . LEU C 1 150 ? 101.850 110.455 103.216 1.00 49.71 ? 150 LEU C CD2 1 
ATOM   7530  N N   . GLN C 1 151 ? 98.366  108.884 99.582  1.00 54.69 ? 151 GLN C N   1 
ATOM   7531  C CA  . GLN C 1 151 ? 97.100  108.369 99.062  1.00 54.69 ? 151 GLN C CA  1 
ATOM   7532  C C   . GLN C 1 151 ? 97.386  107.544 97.817  1.00 54.69 ? 151 GLN C C   1 
ATOM   7533  O O   . GLN C 1 151 ? 97.387  108.081 96.701  1.00 54.69 ? 151 GLN C O   1 
ATOM   7534  C CB  . GLN C 1 151 ? 96.128  109.500 98.738  1.00 54.69 ? 151 GLN C CB  1 
ATOM   7535  C CG  . GLN C 1 151 ? 95.985  110.552 99.821  1.00 54.69 ? 151 GLN C CG  1 
ATOM   7536  C CD  . GLN C 1 151 ? 96.737  111.822 99.493  1.00 54.69 ? 151 GLN C CD  1 
ATOM   7537  O OE1 . GLN C 1 151 ? 97.233  111.986 98.384  1.00 54.69 ? 151 GLN C OE1 1 
ATOM   7538  N NE2 . GLN C 1 151 ? 96.812  112.735 100.452 1.00 54.69 ? 151 GLN C NE2 1 
ATOM   7539  N N   . PRO C 1 152 ? 97.639  106.244 97.953  1.00 57.56 ? 152 PRO C N   1 
ATOM   7540  C CA  . PRO C 1 152 ? 97.948  105.434 96.769  1.00 57.56 ? 152 PRO C CA  1 
ATOM   7541  C C   . PRO C 1 152 ? 96.766  105.370 95.819  1.00 57.56 ? 152 PRO C C   1 
ATOM   7542  O O   . PRO C 1 152 ? 95.606  105.375 96.236  1.00 57.56 ? 152 PRO C O   1 
ATOM   7543  C CB  . PRO C 1 152 ? 98.273  104.058 97.356  1.00 57.56 ? 152 PRO C CB  1 
ATOM   7544  C CG  . PRO C 1 152 ? 98.663  104.336 98.763  1.00 57.56 ? 152 PRO C CG  1 
ATOM   7545  C CD  . PRO C 1 152 ? 97.794  105.474 99.194  1.00 57.56 ? 152 PRO C CD  1 
ATOM   7546  N N   . GLY C 1 153 ? 97.074  105.326 94.526  1.00 57.73 ? 153 GLY C N   1 
ATOM   7547  C CA  . GLY C 1 153 ? 96.057  105.331 93.501  1.00 57.73 ? 153 GLY C CA  1 
ATOM   7548  C C   . GLY C 1 153 ? 95.397  106.667 93.259  1.00 57.73 ? 153 GLY C C   1 
ATOM   7549  O O   . GLY C 1 153 ? 94.497  106.751 92.413  1.00 57.73 ? 153 GLY C O   1 
ATOM   7550  N N   . GLY C 1 154 ? 95.812  107.714 93.961  1.00 60.30 ? 154 GLY C N   1 
ATOM   7551  C CA  . GLY C 1 154 ? 95.203  109.016 93.843  1.00 60.30 ? 154 GLY C CA  1 
ATOM   7552  C C   . GLY C 1 154 ? 95.922  110.010 92.965  1.00 60.30 ? 154 GLY C C   1 
ATOM   7553  O O   . GLY C 1 154 ? 95.482  111.158 92.877  1.00 60.30 ? 154 GLY C O   1 
ATOM   7554  N N   . VAL C 1 155 ? 97.016  109.620 92.318  1.00 58.97 ? 155 VAL C N   1 
ATOM   7555  C CA  . VAL C 1 155 ? 97.799  110.523 91.470  1.00 58.97 ? 155 VAL C CA  1 
ATOM   7556  C C   . VAL C 1 155 ? 98.075  109.797 90.168  1.00 58.97 ? 155 VAL C C   1 
ATOM   7557  O O   . VAL C 1 155 ? 99.041  109.034 90.047  1.00 58.97 ? 155 VAL C O   1 
ATOM   7558  C CB  . VAL C 1 155 ? 99.103  110.970 92.142  1.00 58.97 ? 155 VAL C CB  1 
ATOM   7559  C CG1 . VAL C 1 155 ? 99.892  111.853 91.208  1.00 58.97 ? 155 VAL C CG1 1 
ATOM   7560  C CG2 . VAL C 1 155 ? 98.804  111.700 93.428  1.00 58.97 ? 155 VAL C CG2 1 
ATOM   7561  N N   . ASP C 1 156 ? 97.233  110.028 89.161  1.00 60.35 ? 156 ASP C N   1 
ATOM   7562  C CA  . ASP C 1 156 ? 97.471  109.484 87.836  1.00 60.35 ? 156 ASP C CA  1 
ATOM   7563  C C   . ASP C 1 156 ? 98.454  110.369 87.087  1.00 60.35 ? 156 ASP C C   1 
ATOM   7564  O O   . ASP C 1 156 ? 98.328  111.594 87.080  1.00 60.35 ? 156 ASP C O   1 
ATOM   7565  C CB  . ASP C 1 156 ? 96.161  109.367 87.061  1.00 60.35 ? 156 ASP C CB  1 
ATOM   7566  C CG  . ASP C 1 156 ? 96.327  108.671 85.728  1.00 60.35 ? 156 ASP C CG  1 
ATOM   7567  O OD1 . ASP C 1 156 ? 97.441  108.201 85.432  1.00 60.35 ? 156 ASP C OD1 1 
ATOM   7568  O OD2 . ASP C 1 156 ? 95.340  108.592 84.971  1.00 60.35 ? 156 ASP C OD2 1 
ATOM   7569  N N   . SER C 1 157 ? 99.429  109.739 86.438  1.00 55.59 ? 157 SER C N   1 
ATOM   7570  C CA  . SER C 1 157 ? 100.573 110.446 85.886  1.00 55.59 ? 157 SER C CA  1 
ATOM   7571  C C   . SER C 1 157 ? 100.597 110.450 84.364  1.00 55.59 ? 157 SER C C   1 
ATOM   7572  O O   . SER C 1 157 ? 101.658 110.644 83.772  1.00 55.59 ? 157 SER C O   1 
ATOM   7573  C CB  . SER C 1 157 ? 101.863 109.835 86.427  1.00 55.59 ? 157 SER C CB  1 
ATOM   7574  O OG  . SER C 1 157 ? 102.987 110.606 86.054  1.00 55.59 ? 157 SER C OG  1 
ATOM   7575  N N   . THR C 1 158 ? 99.453  110.252 83.713  1.00 57.68 ? 158 THR C N   1 
ATOM   7576  C CA  . THR C 1 158 ? 99.441  110.181 82.256  1.00 57.68 ? 158 THR C CA  1 
ATOM   7577  C C   . THR C 1 158 ? 99.852  111.505 81.625  1.00 57.68 ? 158 THR C C   1 
ATOM   7578  O O   . THR C 1 158 ? 100.884 111.597 80.949  1.00 57.68 ? 158 THR C O   1 
ATOM   7579  C CB  . THR C 1 158 ? 98.058  109.772 81.769  1.00 57.68 ? 158 THR C CB  1 
ATOM   7580  O OG1 . THR C 1 158 ? 97.711  108.508 82.338  1.00 57.68 ? 158 THR C OG1 1 
ATOM   7581  C CG2 . THR C 1 158 ? 98.063  109.654 80.274  1.00 57.68 ? 158 THR C CG2 1 
ATOM   7582  N N   . MET C 1 159 ? 99.052  112.550 81.838  1.00 58.99 ? 159 MET C N   1 
ATOM   7583  C CA  . MET C 1 159 ? 99.293  113.807 81.142  1.00 58.99 ? 159 MET C CA  1 
ATOM   7584  C C   . MET C 1 159 ? 100.612 114.422 81.559  1.00 58.99 ? 159 MET C C   1 
ATOM   7585  O O   . MET C 1 159 ? 101.270 115.091 80.758  1.00 58.99 ? 159 MET C O   1 
ATOM   7586  C CB  . MET C 1 159 ? 98.159  114.786 81.404  1.00 58.99 ? 159 MET C CB  1 
ATOM   7587  C CG  . MET C 1 159 ? 96.792  114.194 81.255  1.00 58.99 ? 159 MET C CG  1 
ATOM   7588  S SD  . MET C 1 159 ? 95.582  115.507 81.250  1.00 58.99 ? 159 MET C SD  1 
ATOM   7589  C CE  . MET C 1 159 ? 95.894  116.200 79.641  1.00 58.99 ? 159 MET C CE  1 
ATOM   7590  N N   . PHE C 1 160 ? 101.000 114.234 82.818  1.00 51.91 ? 160 PHE C N   1 
ATOM   7591  C CA  . PHE C 1 160 ? 102.335 114.640 83.222  1.00 51.91 ? 160 PHE C CA  1 
ATOM   7592  C C   . PHE C 1 160 ? 103.371 113.960 82.353  1.00 51.91 ? 160 PHE C C   1 
ATOM   7593  O O   . PHE C 1 160 ? 104.309 114.602 81.871  1.00 51.91 ? 160 PHE C O   1 
ATOM   7594  C CB  . PHE C 1 160 ? 102.568 114.315 84.696  1.00 51.91 ? 160 PHE C CB  1 
ATOM   7595  C CG  . PHE C 1 160 ? 103.854 114.863 85.239  1.00 51.91 ? 160 PHE C CG  1 
ATOM   7596  C CD1 . PHE C 1 160 ? 105.054 114.234 84.989  1.00 51.91 ? 160 PHE C CD1 1 
ATOM   7597  C CD2 . PHE C 1 160 ? 103.863 116.008 86.000  1.00 51.91 ? 160 PHE C CD2 1 
ATOM   7598  C CE1 . PHE C 1 160 ? 106.228 114.737 85.478  1.00 51.91 ? 160 PHE C CE1 1 
ATOM   7599  C CE2 . PHE C 1 160 ? 105.041 116.512 86.494  1.00 51.91 ? 160 PHE C CE2 1 
ATOM   7600  C CZ  . PHE C 1 160 ? 106.222 115.876 86.231  1.00 51.91 ? 160 PHE C CZ  1 
ATOM   7601  N N   . ASP C 1 161 ? 103.196 112.661 82.116  1.00 57.62 ? 161 ASP C N   1 
ATOM   7602  C CA  . ASP C 1 161 ? 104.154 111.924 81.307  1.00 57.62 ? 161 ASP C CA  1 
ATOM   7603  C C   . ASP C 1 161 ? 104.193 112.459 79.887  1.00 57.62 ? 161 ASP C C   1 
ATOM   7604  O O   . ASP C 1 161 ? 105.263 112.546 79.278  1.00 57.62 ? 161 ASP C O   1 
ATOM   7605  C CB  . ASP C 1 161 ? 103.807 110.440 81.310  1.00 57.62 ? 161 ASP C CB  1 
ATOM   7606  C CG  . ASP C 1 161 ? 104.077 109.781 82.642  1.00 57.62 ? 161 ASP C CG  1 
ATOM   7607  O OD1 . ASP C 1 161 ? 104.821 110.357 83.459  1.00 57.62 ? 161 ASP C OD1 1 
ATOM   7608  O OD2 . ASP C 1 161 ? 103.530 108.685 82.879  1.00 57.62 ? 161 ASP C OD2 1 
ATOM   7609  N N   . HIS C 1 162 ? 103.037 112.838 79.344  1.00 57.45 ? 162 HIS C N   1 
ATOM   7610  C CA  . HIS C 1 162 ? 103.019 113.296 77.960  1.00 57.45 ? 162 HIS C CA  1 
ATOM   7611  C C   . HIS C 1 162 ? 103.615 114.688 77.814  1.00 57.45 ? 162 HIS C C   1 
ATOM   7612  O O   . HIS C 1 162 ? 104.299 114.969 76.826  1.00 57.45 ? 162 HIS C O   1 
ATOM   7613  C CB  . HIS C 1 162 ? 101.605 113.289 77.398  1.00 57.45 ? 162 HIS C CB  1 
ATOM   7614  C CG  . HIS C 1 162 ? 101.540 113.756 75.980  1.00 57.45 ? 162 HIS C CG  1 
ATOM   7615  N ND1 . HIS C 1 162 ? 101.632 112.895 74.910  1.00 57.45 ? 162 HIS C ND1 1 
ATOM   7616  C CD2 . HIS C 1 162 ? 101.436 114.998 75.455  1.00 57.45 ? 162 HIS C CD2 1 
ATOM   7617  C CE1 . HIS C 1 162 ? 101.570 113.585 73.786  1.00 57.45 ? 162 HIS C CE1 1 
ATOM   7618  N NE2 . HIS C 1 162 ? 101.451 114.864 74.089  1.00 57.45 ? 162 HIS C NE2 1 
ATOM   7619  N N   . PHE C 1 163 ? 103.352 115.580 78.769  1.00 54.05 ? 163 PHE C N   1 
ATOM   7620  C CA  . PHE C 1 163 ? 103.687 116.988 78.598  1.00 54.05 ? 163 PHE C CA  1 
ATOM   7621  C C   . PHE C 1 163 ? 105.023 117.385 79.191  1.00 54.05 ? 163 PHE C C   1 
ATOM   7622  O O   . PHE C 1 163 ? 105.607 118.368 78.733  1.00 54.05 ? 163 PHE C O   1 
ATOM   7623  C CB  . PHE C 1 163 ? 102.609 117.870 79.215  1.00 54.05 ? 163 PHE C CB  1 
ATOM   7624  C CG  . PHE C 1 163 ? 101.407 118.015 78.363  1.00 54.05 ? 163 PHE C CG  1 
ATOM   7625  C CD1 . PHE C 1 163 ? 101.457 118.751 77.204  1.00 54.05 ? 163 PHE C CD1 1 
ATOM   7626  C CD2 . PHE C 1 163 ? 100.225 117.411 78.714  1.00 54.05 ? 163 PHE C CD2 1 
ATOM   7627  C CE1 . PHE C 1 163 ? 100.349 118.883 76.416  1.00 54.05 ? 163 PHE C CE1 1 
ATOM   7628  C CE2 . PHE C 1 163 ? 99.114  117.543 77.924  1.00 54.05 ? 163 PHE C CE2 1 
ATOM   7629  C CZ  . PHE C 1 163 ? 99.178  118.279 76.775  1.00 54.05 ? 163 PHE C CZ  1 
ATOM   7630  N N   . TYR C 1 164 ? 105.515 116.678 80.200  1.00 52.72 ? 164 TYR C N   1 
ATOM   7631  C CA  . TYR C 1 164 ? 106.850 116.967 80.704  1.00 52.72 ? 164 TYR C CA  1 
ATOM   7632  C C   . TYR C 1 164 ? 107.912 117.001 79.613  1.00 52.72 ? 164 TYR C C   1 
ATOM   7633  O O   . TYR C 1 164 ? 108.848 117.809 79.733  1.00 52.72 ? 164 TYR C O   1 
ATOM   7634  C CB  . TYR C 1 164 ? 107.215 115.946 81.789  1.00 52.72 ? 164 TYR C CB  1 
ATOM   7635  C CG  . TYR C 1 164 ? 108.510 116.241 82.501  1.00 52.72 ? 164 TYR C CG  1 
ATOM   7636  C CD1 . TYR C 1 164 ? 108.554 117.129 83.556  1.00 52.72 ? 164 TYR C CD1 1 
ATOM   7637  C CD2 . TYR C 1 164 ? 109.688 115.630 82.118  1.00 52.72 ? 164 TYR C CD2 1 
ATOM   7638  C CE1 . TYR C 1 164 ? 109.732 117.403 84.207  1.00 52.72 ? 164 TYR C CE1 1 
ATOM   7639  C CE2 . TYR C 1 164 ? 110.868 115.895 82.765  1.00 52.72 ? 164 TYR C CE2 1 
ATOM   7640  C CZ  . TYR C 1 164 ? 110.885 116.784 83.808  1.00 52.72 ? 164 TYR C CZ  1 
ATOM   7641  O OH  . TYR C 1 164 ? 112.062 117.055 84.459  1.00 52.72 ? 164 TYR C OH  1 
ATOM   7642  N N   . PRO C 1 165 ? 107.857 116.184 78.557  1.00 52.85 ? 165 PRO C N   1 
ATOM   7643  C CA  . PRO C 1 165 ? 108.869 116.331 77.501  1.00 52.85 ? 165 PRO C CA  1 
ATOM   7644  C C   . PRO C 1 165 ? 108.684 117.567 76.642  1.00 52.85 ? 165 PRO C C   1 
ATOM   7645  O O   . PRO C 1 165 ? 109.669 118.231 76.299  1.00 52.85 ? 165 PRO C O   1 
ATOM   7646  C CB  . PRO C 1 165 ? 108.696 115.048 76.682  1.00 52.85 ? 165 PRO C CB  1 
ATOM   7647  C CG  . PRO C 1 165 ? 108.010 114.114 77.574  1.00 52.85 ? 165 PRO C CG  1 
ATOM   7648  C CD  . PRO C 1 165 ? 107.106 114.930 78.394  1.00 52.85 ? 165 PRO C CD  1 
ATOM   7649  N N   . LEU C 1 166 ? 107.447 117.901 76.285  1.00 53.86 ? 166 LEU C N   1 
ATOM   7650  C CA  . LEU C 1 166 ? 107.213 118.936 75.287  1.00 53.86 ? 166 LEU C CA  1 
ATOM   7651  C C   . LEU C 1 166 ? 107.261 120.332 75.891  1.00 53.86 ? 166 LEU C C   1 
ATOM   7652  O O   . LEU C 1 166 ? 107.862 121.241 75.313  1.00 53.86 ? 166 LEU C O   1 
ATOM   7653  C CB  . LEU C 1 166 ? 105.872 118.693 74.609  1.00 53.86 ? 166 LEU C CB  1 
ATOM   7654  C CG  . LEU C 1 166 ? 105.680 117.227 74.240  1.00 53.86 ? 166 LEU C CG  1 
ATOM   7655  C CD1 . LEU C 1 166 ? 104.298 116.976 73.696  1.00 53.86 ? 166 LEU C CD1 1 
ATOM   7656  C CD2 . LEU C 1 166 ? 106.729 116.826 73.233  1.00 53.86 ? 166 LEU C CD2 1 
ATOM   7657  N N   . LEU C 1 167 ? 106.631 120.525 77.046  1.00 56.08 ? 167 LEU C N   1 
ATOM   7658  C CA  . LEU C 1 167 ? 106.553 121.846 77.654  1.00 56.08 ? 167 LEU C CA  1 
ATOM   7659  C C   . LEU C 1 167 ? 107.697 122.128 78.612  1.00 56.08 ? 167 LEU C C   1 
ATOM   7660  O O   . LEU C 1 167 ? 108.383 123.141 78.474  1.00 56.08 ? 167 LEU C O   1 
ATOM   7661  C CB  . LEU C 1 167 ? 105.239 122.001 78.410  1.00 56.08 ? 167 LEU C CB  1 
ATOM   7662  C CG  . LEU C 1 167 ? 103.957 121.914 77.602  1.00 56.08 ? 167 LEU C CG  1 
ATOM   7663  C CD1 . LEU C 1 167 ? 102.791 121.881 78.552  1.00 56.08 ? 167 LEU C CD1 1 
ATOM   7664  C CD2 . LEU C 1 167 ? 103.848 123.087 76.662  1.00 56.08 ? 167 LEU C CD2 1 
ATOM   7665  N N   . CYS C 1 168 ? 107.908 121.261 79.590  1.00 56.06 ? 168 CYS C N   1 
ATOM   7666  C CA  . CYS C 1 168 ? 108.849 121.544 80.654  1.00 56.06 ? 168 CYS C CA  1 
ATOM   7667  C C   . CYS C 1 168 ? 110.273 121.312 80.177  1.00 56.06 ? 168 CYS C C   1 
ATOM   7668  O O   . CYS C 1 168 ? 110.523 120.927 79.035  1.00 56.06 ? 168 CYS C O   1 
ATOM   7669  C CB  . CYS C 1 168 ? 108.542 120.689 81.878  1.00 56.06 ? 168 CYS C CB  1 
ATOM   7670  S SG  . CYS C 1 168 ? 109.624 120.996 83.277  1.00 56.06 ? 168 CYS C SG  1 
ATOM   7671  N N   . VAL C 1 169 ? 111.222 121.559 81.068  1.00 58.27 ? 169 VAL C N   1 
ATOM   7672  C CA  . VAL C 1 169 ? 112.628 121.304 80.813  1.00 58.27 ? 169 VAL C CA  1 
ATOM   7673  C C   . VAL C 1 169 ? 113.206 120.605 82.029  1.00 58.27 ? 169 VAL C C   1 
ATOM   7674  O O   . VAL C 1 169 ? 113.095 121.112 83.150  1.00 58.27 ? 169 VAL C O   1 
ATOM   7675  C CB  . VAL C 1 169 ? 113.405 122.596 80.521  1.00 58.27 ? 169 VAL C CB  1 
ATOM   7676  C CG1 . VAL C 1 169 ? 114.880 122.323 80.578  1.00 58.27 ? 169 VAL C CG1 1 
ATOM   7677  C CG2 . VAL C 1 169 ? 113.031 123.131 79.164  1.00 58.27 ? 169 VAL C CG2 1 
ATOM   7678  N N   . ASP C 1 170 ? 113.815 119.447 81.811  1.00 61.31 ? 170 ASP C N   1 
ATOM   7679  C CA  . ASP C 1 170 ? 114.419 118.697 82.896  1.00 61.31 ? 170 ASP C CA  1 
ATOM   7680  C C   . ASP C 1 170 ? 115.692 119.386 83.365  1.00 61.31 ? 170 ASP C C   1 
ATOM   7681  O O   . ASP C 1 170 ? 116.129 120.396 82.812  1.00 61.31 ? 170 ASP C O   1 
ATOM   7682  C CB  . ASP C 1 170 ? 114.709 117.269 82.452  1.00 61.31 ? 170 ASP C CB  1 
ATOM   7683  C CG  . ASP C 1 170 ? 115.302 117.214 81.067  1.00 61.31 ? 170 ASP C CG  1 
ATOM   7684  O OD1 . ASP C 1 170 ? 115.196 118.231 80.357  1.00 61.31 ? 170 ASP C OD1 1 
ATOM   7685  O OD2 . ASP C 1 170 ? 115.878 116.172 80.690  1.00 61.31 ? 170 ASP C OD2 1 
ATOM   7686  N N   . GLY C 1 171 ? 116.295 118.825 84.401  1.00 58.99 ? 171 GLY C N   1 
ATOM   7687  C CA  . GLY C 1 171 ? 117.532 119.331 84.933  1.00 58.99 ? 171 GLY C CA  1 
ATOM   7688  C C   . GLY C 1 171 ? 118.657 119.379 83.924  1.00 58.99 ? 171 GLY C C   1 
ATOM   7689  O O   . GLY C 1 171 ? 119.263 120.431 83.702  1.00 58.99 ? 171 GLY C O   1 
ATOM   7690  N N   . PRO C 1 172 ? 118.972 118.241 83.296  1.00 59.67 ? 172 PRO C N   1 
ATOM   7691  C CA  . PRO C 1 172 ? 120.133 118.222 82.393  1.00 59.67 ? 172 PRO C CA  1 
ATOM   7692  C C   . PRO C 1 172 ? 119.982 119.120 81.181  1.00 59.67 ? 172 PRO C C   1 
ATOM   7693  O O   . PRO C 1 172 ? 120.939 119.807 80.808  1.00 59.67 ? 172 PRO C O   1 
ATOM   7694  C CB  . PRO C 1 172 ? 120.237 116.744 82.002  1.00 59.67 ? 172 PRO C CB  1 
ATOM   7695  C CG  . PRO C 1 172 ? 119.597 116.027 83.115  1.00 59.67 ? 172 PRO C CG  1 
ATOM   7696  C CD  . PRO C 1 172 ? 118.453 116.883 83.524  1.00 59.67 ? 172 PRO C CD  1 
ATOM   7697  N N   . GLU C 1 173 ? 118.812 119.134 80.548  1.00 62.00 ? 173 GLU C N   1 
ATOM   7698  C CA  . GLU C 1 173 ? 118.615 120.008 79.399  1.00 62.00 ? 173 GLU C CA  1 
ATOM   7699  C C   . GLU C 1 173 ? 118.785 121.467 79.784  1.00 62.00 ? 173 GLU C C   1 
ATOM   7700  O O   . GLU C 1 173 ? 119.424 122.238 79.061  1.00 62.00 ? 173 GLU C O   1 
ATOM   7701  C CB  . GLU C 1 173 ? 117.233 119.774 78.803  1.00 62.00 ? 173 GLU C CB  1 
ATOM   7702  C CG  . GLU C 1 173 ? 116.906 120.622 77.607  1.00 62.00 ? 173 GLU C CG  1 
ATOM   7703  C CD  . GLU C 1 173 ? 115.578 120.239 77.006  1.00 62.00 ? 173 GLU C CD  1 
ATOM   7704  O OE1 . GLU C 1 173 ? 114.798 119.550 77.695  1.00 62.00 ? 173 GLU C OE1 1 
ATOM   7705  O OE2 . GLU C 1 173 ? 115.312 120.618 75.848  1.00 62.00 ? 173 GLU C OE2 1 
ATOM   7706  N N   . ALA C 1 174 ? 118.222 121.864 80.925  1.00 59.20 ? 174 ALA C N   1 
ATOM   7707  C CA  . ALA C 1 174 ? 118.378 123.236 81.382  1.00 59.20 ? 174 ALA C CA  1 
ATOM   7708  C C   . ALA C 1 174 ? 119.825 123.551 81.714  1.00 59.20 ? 174 ALA C C   1 
ATOM   7709  O O   . ALA C 1 174 ? 120.269 124.685 81.524  1.00 59.20 ? 174 ALA C O   1 
ATOM   7710  C CB  . ALA C 1 174 ? 117.492 123.490 82.597  1.00 59.20 ? 174 ALA C CB  1 
ATOM   7711  N N   . ARG C 1 175 ? 120.577 122.569 82.202  1.00 58.15 ? 175 ARG C N   1 
ATOM   7712  C CA  . ARG C 1 175 ? 121.962 122.837 82.552  1.00 58.15 ? 175 ARG C CA  1 
ATOM   7713  C C   . ARG C 1 175 ? 122.859 122.919 81.326  1.00 58.15 ? 175 ARG C C   1 
ATOM   7714  O O   . ARG C 1 175 ? 123.837 123.674 81.335  1.00 58.15 ? 175 ARG C O   1 
ATOM   7715  C CB  . ARG C 1 175 ? 122.479 121.772 83.513  1.00 58.15 ? 175 ARG C CB  1 
ATOM   7716  C CG  . ARG C 1 175 ? 121.920 121.900 84.912  1.00 58.15 ? 175 ARG C CG  1 
ATOM   7717  C CD  . ARG C 1 175 ? 122.804 121.220 85.937  1.00 58.15 ? 175 ARG C CD  1 
ATOM   7718  N NE  . ARG C 1 175 ? 122.789 119.768 85.802  1.00 58.15 ? 175 ARG C NE  1 
ATOM   7719  C CZ  . ARG C 1 175 ? 121.781 118.986 86.175  1.00 58.15 ? 175 ARG C CZ  1 
ATOM   7720  N NH1 . ARG C 1 175 ? 120.688 119.509 86.710  1.00 58.15 ? 175 ARG C NH1 1 
ATOM   7721  N NH2 . ARG C 1 175 ? 121.868 117.676 86.012  1.00 58.15 ? 175 ARG C NH2 1 
ATOM   7722  N N   . ARG C 1 176 ? 122.557 122.163 80.269  1.00 63.42 ? 176 ARG C N   1 
ATOM   7723  C CA  . ARG C 1 176 ? 123.380 122.240 79.065  1.00 63.42 ? 176 ARG C CA  1 
ATOM   7724  C C   . ARG C 1 176 ? 123.225 123.589 78.380  1.00 63.42 ? 176 ARG C C   1 
ATOM   7725  O O   . ARG C 1 176 ? 124.198 124.149 77.866  1.00 63.42 ? 176 ARG C O   1 
ATOM   7726  C CB  . ARG C 1 176 ? 123.019 121.116 78.094  1.00 63.42 ? 176 ARG C CB  1 
ATOM   7727  C CG  . ARG C 1 176 ? 123.254 119.719 78.630  1.00 63.42 ? 176 ARG C CG  1 
ATOM   7728  C CD  . ARG C 1 176 ? 123.058 118.660 77.561  1.00 63.42 ? 176 ARG C CD  1 
ATOM   7729  N NE  . ARG C 1 176 ? 121.885 118.910 76.729  1.00 63.42 ? 176 ARG C NE  1 
ATOM   7730  C CZ  . ARG C 1 176 ? 120.722 118.281 76.857  1.00 63.42 ? 176 ARG C CZ  1 
ATOM   7731  N NH1 . ARG C 1 176 ? 120.562 117.358 77.789  1.00 63.42 ? 176 ARG C NH1 1 
ATOM   7732  N NH2 . ARG C 1 176 ? 119.715 118.575 76.048  1.00 63.42 ? 176 ARG C NH2 1 
ATOM   7733  N N   . GLN C 1 177 ? 122.012 124.123 78.368  1.00 64.59 ? 177 GLN C N   1 
ATOM   7734  C CA  . GLN C 1 177 ? 121.680 125.353 77.663  1.00 64.59 ? 177 GLN C CA  1 
ATOM   7735  C C   . GLN C 1 177 ? 121.506 126.527 78.620  1.00 64.59 ? 177 GLN C C   1 
ATOM   7736  O O   . GLN C 1 177 ? 120.591 127.333 78.468  1.00 64.59 ? 177 GLN C O   1 
ATOM   7737  C CB  . GLN C 1 177 ? 120.424 125.158 76.822  1.00 64.59 ? 177 GLN C CB  1 
ATOM   7738  C CG  . GLN C 1 177 ? 120.669 124.380 75.545  1.00 64.59 ? 177 GLN C CG  1 
ATOM   7739  C CD  . GLN C 1 177 ? 119.412 123.750 74.995  1.00 64.59 ? 177 GLN C CD  1 
ATOM   7740  O OE1 . GLN C 1 177 ? 118.398 123.669 75.680  1.00 64.59 ? 177 GLN C OE1 1 
ATOM   7741  N NE2 . GLN C 1 177 ? 119.473 123.293 73.753  1.00 64.59 ? 177 GLN C NE2 1 
ATOM   7742  N N   . TRP C 1 178 ? 122.366 126.624 79.636  1.00 63.18 ? 178 TRP C N   1 
ATOM   7743  C CA  . TRP C 1 178 ? 122.191 127.680 80.626  1.00 63.18 ? 178 TRP C CA  1 
ATOM   7744  C C   . TRP C 1 178 ? 122.429 129.059 80.037  1.00 63.18 ? 178 TRP C C   1 
ATOM   7745  O O   . TRP C 1 178 ? 121.844 130.041 80.506  1.00 63.18 ? 178 TRP C O   1 
ATOM   7746  C CB  . TRP C 1 178 ? 123.119 127.477 81.813  1.00 63.18 ? 178 TRP C CB  1 
ATOM   7747  C CG  . TRP C 1 178 ? 122.736 128.367 82.930  1.00 63.18 ? 178 TRP C CG  1 
ATOM   7748  C CD1 . TRP C 1 178 ? 123.440 129.422 83.414  1.00 63.18 ? 178 TRP C CD1 1 
ATOM   7749  C CD2 . TRP C 1 178 ? 121.529 128.304 83.690  1.00 63.18 ? 178 TRP C CD2 1 
ATOM   7750  N NE1 . TRP C 1 178 ? 122.754 130.012 84.445  1.00 63.18 ? 178 TRP C NE1 1 
ATOM   7751  C CE2 . TRP C 1 178 ? 121.575 129.340 84.633  1.00 63.18 ? 178 TRP C CE2 1 
ATOM   7752  C CE3 . TRP C 1 178 ? 120.418 127.463 83.671  1.00 63.18 ? 178 TRP C CE3 1 
ATOM   7753  C CZ2 . TRP C 1 178 ? 120.554 129.558 85.547  1.00 63.18 ? 178 TRP C CZ2 1 
ATOM   7754  C CZ3 . TRP C 1 178 ? 119.409 127.682 84.577  1.00 63.18 ? 178 TRP C CZ3 1 
ATOM   7755  C CH2 . TRP C 1 178 ? 119.483 128.717 85.503  1.00 63.18 ? 178 TRP C CH2 1 
ATOM   7756  N N   . ASP C 1 179 ? 123.296 129.154 79.034  1.00 67.16 ? 179 ASP C N   1 
ATOM   7757  C CA  . ASP C 1 179 ? 123.518 130.426 78.364  1.00 67.16 ? 179 ASP C CA  1 
ATOM   7758  C C   . ASP C 1 179 ? 122.222 131.018 77.833  1.00 67.16 ? 179 ASP C C   1 
ATOM   7759  O O   . ASP C 1 179 ? 122.093 132.241 77.733  1.00 67.16 ? 179 ASP C O   1 
ATOM   7760  C CB  . ASP C 1 179 ? 124.514 130.219 77.233  1.00 67.16 ? 179 ASP C CB  1 
ATOM   7761  C CG  . ASP C 1 179 ? 124.067 129.141 76.260  1.00 67.16 ? 179 ASP C CG  1 
ATOM   7762  O OD1 . ASP C 1 179 ? 122.995 128.541 76.482  1.00 67.16 ? 179 ASP C OD1 1 
ATOM   7763  O OD2 . ASP C 1 179 ? 124.796 128.881 75.281  1.00 67.16 ? 179 ASP C OD2 1 
ATOM   7764  N N   . SER C 1 180 ? 121.247 130.171 77.510  1.00 63.74 ? 180 SER C N   1 
ATOM   7765  C CA  . SER C 1 180 ? 120.045 130.645 76.837  1.00 63.74 ? 180 SER C CA  1 
ATOM   7766  C C   . SER C 1 180 ? 119.065 131.288 77.807  1.00 63.74 ? 180 SER C C   1 
ATOM   7767  O O   . SER C 1 180 ? 118.460 132.316 77.490  1.00 63.74 ? 180 SER C O   1 
ATOM   7768  C CB  . SER C 1 180 ? 119.380 129.488 76.098  1.00 63.74 ? 180 SER C CB  1 
ATOM   7769  O OG  . SER C 1 180 ? 118.025 129.771 75.830  1.00 63.74 ? 180 SER C OG  1 
ATOM   7770  N N   . ILE C 1 181 ? 118.889 130.706 78.988  1.00 64.98 ? 181 ILE C N   1 
ATOM   7771  C CA  . ILE C 1 181 ? 117.814 131.101 79.887  1.00 64.98 ? 181 ILE C CA  1 
ATOM   7772  C C   . ILE C 1 181 ? 118.330 131.819 81.123  1.00 64.98 ? 181 ILE C C   1 
ATOM   7773  O O   . ILE C 1 181 ? 117.555 132.089 82.043  1.00 64.98 ? 181 ILE C O   1 
ATOM   7774  C CB  . ILE C 1 181 ? 116.961 129.893 80.289  1.00 64.98 ? 181 ILE C CB  1 
ATOM   7775  C CG1 . ILE C 1 181 ? 117.855 128.790 80.849  1.00 64.98 ? 181 ILE C CG1 1 
ATOM   7776  C CG2 . ILE C 1 181 ? 116.185 129.392 79.105  1.00 64.98 ? 181 ILE C CG2 1 
ATOM   7777  C CD1 . ILE C 1 181 ? 117.095 127.643 81.452  1.00 64.98 ? 181 ILE C CD1 1 
ATOM   7778  N N   . ALA C 1 182 ? 119.621 132.138 81.171  1.00 66.24 ? 182 ALA C N   1 
ATOM   7779  C CA  . ALA C 1 182 ? 120.162 132.785 82.359  1.00 66.24 ? 182 ALA C CA  1 
ATOM   7780  C C   . ALA C 1 182 ? 119.587 134.182 82.540  1.00 66.24 ? 182 ALA C C   1 
ATOM   7781  O O   . ALA C 1 182 ? 119.372 134.628 83.671  1.00 66.24 ? 182 ALA C O   1 
ATOM   7782  C CB  . ALA C 1 182 ? 121.685 132.835 82.281  1.00 66.24 ? 182 ALA C CB  1 
ATOM   7783  N N   . HIS C 1 183 ? 119.322 134.887 81.440  1.00 66.69 ? 183 HIS C N   1 
ATOM   7784  C CA  . HIS C 1 183 ? 118.802 136.244 81.537  1.00 66.69 ? 183 HIS C CA  1 
ATOM   7785  C C   . HIS C 1 183 ? 117.388 136.295 82.098  1.00 66.69 ? 183 HIS C C   1 
ATOM   7786  O O   . HIS C 1 183 ? 116.933 137.373 82.489  1.00 66.69 ? 183 HIS C O   1 
ATOM   7787  C CB  . HIS C 1 183 ? 118.819 136.911 80.170  1.00 66.69 ? 183 HIS C CB  1 
ATOM   7788  C CG  . HIS C 1 183 ? 117.739 136.425 79.264  1.00 66.69 ? 183 HIS C CG  1 
ATOM   7789  N ND1 . HIS C 1 183 ? 117.921 135.380 78.387  1.00 66.69 ? 183 HIS C ND1 1 
ATOM   7790  C CD2 . HIS C 1 183 ? 116.456 136.823 79.115  1.00 66.69 ? 183 HIS C CD2 1 
ATOM   7791  C CE1 . HIS C 1 183 ? 116.799 135.162 77.728  1.00 66.69 ? 183 HIS C CE1 1 
ATOM   7792  N NE2 . HIS C 1 183 ? 115.893 136.022 78.152  1.00 66.69 ? 183 HIS C NE2 1 
ATOM   7793  N N   . ILE C 1 184 ? 116.671 135.172 82.125  1.00 62.49 ? 184 ILE C N   1 
ATOM   7794  C CA  . ILE C 1 184 ? 115.317 135.182 82.657  1.00 62.49 ? 184 ILE C CA  1 
ATOM   7795  C C   . ILE C 1 184 ? 115.367 135.426 84.155  1.00 62.49 ? 184 ILE C C   1 
ATOM   7796  O O   . ILE C 1 184 ? 116.240 134.904 84.860  1.00 62.49 ? 184 ILE C O   1 
ATOM   7797  C CB  . ILE C 1 184 ? 114.591 133.868 82.334  1.00 62.49 ? 184 ILE C CB  1 
ATOM   7798  C CG1 . ILE C 1 184 ? 114.474 133.696 80.827  1.00 62.49 ? 184 ILE C CG1 1 
ATOM   7799  C CG2 . ILE C 1 184 ? 113.212 133.851 82.951  1.00 62.49 ? 184 ILE C CG2 1 
ATOM   7800  C CD1 . ILE C 1 184 ? 113.621 132.527 80.430  1.00 62.49 ? 184 ILE C CD1 1 
ATOM   7801  N N   . TYR C 1 185 ? 114.434 136.237 84.649  1.00 58.96 ? 185 TYR C N   1 
ATOM   7802  C CA  . TYR C 1 185 ? 114.401 136.537 86.073  1.00 58.96 ? 185 TYR C CA  1 
ATOM   7803  C C   . TYR C 1 185 ? 113.735 135.419 86.862  1.00 58.96 ? 185 TYR C C   1 
ATOM   7804  O O   . TYR C 1 185 ? 114.313 134.894 87.819  1.00 58.96 ? 185 TYR C O   1 
ATOM   7805  C CB  . TYR C 1 185 ? 113.680 137.856 86.320  1.00 58.96 ? 185 TYR C CB  1 
ATOM   7806  C CG  . TYR C 1 185 ? 113.737 138.272 87.763  1.00 58.96 ? 185 TYR C CG  1 
ATOM   7807  C CD1 . TYR C 1 185 ? 114.954 138.491 88.387  1.00 58.96 ? 185 TYR C CD1 1 
ATOM   7808  C CD2 . TYR C 1 185 ? 112.580 138.428 88.507  1.00 58.96 ? 185 TYR C CD2 1 
ATOM   7809  C CE1 . TYR C 1 185 ? 115.018 138.861 89.704  1.00 58.96 ? 185 TYR C CE1 1 
ATOM   7810  C CE2 . TYR C 1 185 ? 112.635 138.799 89.826  1.00 58.96 ? 185 TYR C CE2 1 
ATOM   7811  C CZ  . TYR C 1 185 ? 113.856 139.015 90.420  1.00 58.96 ? 185 TYR C CZ  1 
ATOM   7812  O OH  . TYR C 1 185 ? 113.918 139.388 91.740  1.00 58.96 ? 185 TYR C OH  1 
ATOM   7813  N N   . HIS C 1 186 ? 112.525 135.041 86.478  1.00 57.62 ? 186 HIS C N   1 
ATOM   7814  C CA  . HIS C 1 186 ? 111.787 133.990 87.162  1.00 57.62 ? 186 HIS C CA  1 
ATOM   7815  C C   . HIS C 1 186 ? 111.865 132.719 86.327  1.00 57.62 ? 186 HIS C C   1 
ATOM   7816  O O   . HIS C 1 186 ? 111.216 132.614 85.284  1.00 57.62 ? 186 HIS C O   1 
ATOM   7817  C CB  . HIS C 1 186 ? 110.342 134.413 87.387  1.00 57.62 ? 186 HIS C CB  1 
ATOM   7818  C CG  . HIS C 1 186 ? 109.628 133.580 88.397  1.00 57.62 ? 186 HIS C CG  1 
ATOM   7819  N ND1 . HIS C 1 186 ? 108.255 133.503 88.460  1.00 57.62 ? 186 HIS C ND1 1 
ATOM   7820  C CD2 . HIS C 1 186 ? 110.096 132.785 89.385  1.00 57.62 ? 186 HIS C CD2 1 
ATOM   7821  C CE1 . HIS C 1 186 ? 107.907 132.698 89.446  1.00 57.62 ? 186 HIS C CE1 1 
ATOM   7822  N NE2 . HIS C 1 186 ? 109.006 132.249 90.023  1.00 57.62 ? 186 HIS C NE2 1 
ATOM   7823  N N   . LYS C 1 187 ? 112.662 131.757 86.785  1.00 56.83 ? 187 LYS C N   1 
ATOM   7824  C CA  . LYS C 1 187 ? 112.823 130.485 86.085  1.00 56.83 ? 187 LYS C CA  1 
ATOM   7825  C C   . LYS C 1 187 ? 111.856 129.440 86.641  1.00 56.83 ? 187 LYS C C   1 
ATOM   7826  O O   . LYS C 1 187 ? 112.236 128.367 87.094  1.00 56.83 ? 187 LYS C O   1 
ATOM   7827  C CB  . LYS C 1 187 ? 114.265 130.012 86.184  1.00 56.83 ? 187 LYS C CB  1 
ATOM   7828  C CG  . LYS C 1 187 ? 115.255 131.106 85.924  1.00 56.83 ? 187 LYS C CG  1 
ATOM   7829  C CD  . LYS C 1 187 ? 116.661 130.584 85.909  1.00 56.83 ? 187 LYS C CD  1 
ATOM   7830  C CE  . LYS C 1 187 ? 117.652 131.689 85.574  1.00 56.83 ? 187 LYS C CE  1 
ATOM   7831  N NZ  . LYS C 1 187 ? 118.181 132.379 86.783  1.00 56.83 ? 187 LYS C NZ  1 
ATOM   7832  N N   . CYS C 1 188 ? 110.578 129.782 86.589  1.00 53.97 ? 188 CYS C N   1 
ATOM   7833  C CA  . CYS C 1 188 ? 109.519 128.902 87.049  1.00 53.97 ? 188 CYS C CA  1 
ATOM   7834  C C   . CYS C 1 188 ? 109.089 127.985 85.915  1.00 53.97 ? 188 CYS C C   1 
ATOM   7835  O O   . CYS C 1 188 ? 108.847 128.447 84.798  1.00 53.97 ? 188 CYS C O   1 
ATOM   7836  C CB  . CYS C 1 188 ? 108.333 129.721 87.545  1.00 53.97 ? 188 CYS C CB  1 
ATOM   7837  S SG  . CYS C 1 188 ? 106.872 128.764 87.877  1.00 53.97 ? 188 CYS C SG  1 
ATOM   7838  N N   . HIS C 1 189 ? 108.999 126.691 86.197  1.00 52.94 ? 189 HIS C N   1 
ATOM   7839  C CA  . HIS C 1 189 ? 108.625 125.718 85.183  1.00 52.94 ? 189 HIS C CA  1 
ATOM   7840  C C   . HIS C 1 189 ? 107.528 124.761 85.607  1.00 52.94 ? 189 HIS C C   1 
ATOM   7841  O O   . HIS C 1 189 ? 106.951 124.100 84.738  1.00 52.94 ? 189 HIS C O   1 
ATOM   7842  C CB  . HIS C 1 189 ? 109.847 124.897 84.742  1.00 52.94 ? 189 HIS C CB  1 
ATOM   7843  C CG  . HIS C 1 189 ? 110.633 124.313 85.873  1.00 52.94 ? 189 HIS C CG  1 
ATOM   7844  N ND1 . HIS C 1 189 ? 110.117 123.369 86.732  1.00 52.94 ? 189 HIS C ND1 1 
ATOM   7845  C CD2 . HIS C 1 189 ? 111.908 124.525 86.273  1.00 52.94 ? 189 HIS C CD2 1 
ATOM   7846  C CE1 . HIS C 1 189 ? 111.036 123.032 87.618  1.00 52.94 ? 189 HIS C CE1 1 
ATOM   7847  N NE2 . HIS C 1 189 ? 112.132 123.720 87.362  1.00 52.94 ? 189 HIS C NE2 1 
ATOM   7848  N N   . THR C 1 190 ? 107.217 124.659 86.893  1.00 50.93 ? 190 THR C N   1 
ATOM   7849  C CA  . THR C 1 190 ? 106.205 123.727 87.367  1.00 50.93 ? 190 THR C CA  1 
ATOM   7850  C C   . THR C 1 190 ? 105.532 124.362 88.568  1.00 50.93 ? 190 THR C C   1 
ATOM   7851  O O   . THR C 1 190 ? 106.211 124.707 89.537  1.00 50.93 ? 190 THR C O   1 
ATOM   7852  C CB  . THR C 1 190 ? 106.828 122.391 87.761  1.00 50.93 ? 190 THR C CB  1 
ATOM   7853  O OG1 . THR C 1 190 ? 107.613 121.881 86.681  1.00 50.93 ? 190 THR C OG1 1 
ATOM   7854  C CG2 . THR C 1 190 ? 105.742 121.390 88.089  1.00 50.93 ? 190 THR C CG2 1 
ATOM   7855  N N   . VAL C 1 191 ? 104.217 124.521 88.516  1.00 47.40 ? 191 VAL C N   1 
ATOM   7856  C CA  . VAL C 1 191 ? 103.474 125.103 89.627  1.00 47.40 ? 191 VAL C CA  1 
ATOM   7857  C C   . VAL C 1 191 ? 102.415 124.104 90.054  1.00 47.40 ? 191 VAL C C   1 
ATOM   7858  O O   . VAL C 1 191 ? 101.681 123.584 89.210  1.00 47.40 ? 191 VAL C O   1 
ATOM   7859  C CB  . VAL C 1 191 ? 102.832 126.443 89.239  1.00 47.40 ? 191 VAL C CB  1 
ATOM   7860  C CG1 . VAL C 1 191 ? 102.146 127.051 90.422  1.00 47.40 ? 191 VAL C CG1 1 
ATOM   7861  C CG2 . VAL C 1 191 ? 103.861 127.372 88.696  1.00 47.40 ? 191 VAL C CG2 1 
ATOM   7862  N N   . THR C 1 192 ? 102.331 123.828 91.353  1.00 44.07 ? 192 THR C N   1 
ATOM   7863  C CA  . THR C 1 192 ? 101.449 122.787 91.855  1.00 44.07 ? 192 THR C CA  1 
ATOM   7864  C C   . THR C 1 192 ? 100.386 123.395 92.748  1.00 44.07 ? 192 THR C C   1 
ATOM   7865  O O   . THR C 1 192 ? 100.698 124.106 93.706  1.00 44.07 ? 192 THR C O   1 
ATOM   7866  C CB  . THR C 1 192 ? 102.222 121.730 92.636  1.00 44.07 ? 192 THR C CB  1 
ATOM   7867  O OG1 . THR C 1 192 ? 102.995 122.367 93.656  1.00 44.07 ? 192 THR C OG1 1 
ATOM   7868  C CG2 . THR C 1 192 ? 103.150 120.955 91.720  1.00 44.07 ? 192 THR C CG2 1 
ATOM   7869  N N   . ALA C 1 193 ? 99.137  123.099 92.439  1.00 44.86 ? 193 ALA C N   1 
ATOM   7870  C CA  . ALA C 1 193 ? 98.011  123.531 93.245  1.00 44.86 ? 193 ALA C CA  1 
ATOM   7871  C C   . ALA C 1 193 ? 97.356  122.319 93.884  1.00 44.86 ? 193 ALA C C   1 
ATOM   7872  O O   . ALA C 1 193 ? 97.133  121.305 93.222  1.00 44.86 ? 193 ALA C O   1 
ATOM   7873  C CB  . ALA C 1 193 ? 96.995  124.299 92.406  1.00 44.86 ? 193 ALA C CB  1 
ATOM   7874  N N   . LEU C 1 194 ? 97.054  122.426 95.166  1.00 42.74 ? 194 LEU C N   1 
ATOM   7875  C CA  . LEU C 1 194 ? 96.401  121.374 95.919  1.00 42.74 ? 194 LEU C CA  1 
ATOM   7876  C C   . LEU C 1 194 ? 94.953  121.769 96.125  1.00 42.74 ? 194 LEU C C   1 
ATOM   7877  O O   . LEU C 1 194 ? 94.671  122.862 96.622  1.00 42.74 ? 194 LEU C O   1 
ATOM   7878  C CB  . LEU C 1 194 ? 97.078  121.168 97.271  1.00 42.74 ? 194 LEU C CB  1 
ATOM   7879  C CG  . LEU C 1 194 ? 98.374  120.376 97.380  1.00 42.74 ? 194 LEU C CG  1 
ATOM   7880  C CD1 . LEU C 1 194 ? 98.110  118.957 96.987  1.00 42.74 ? 194 LEU C CD1 1 
ATOM   7881  C CD2 . LEU C 1 194 ? 99.479  120.977 96.534  1.00 42.74 ? 194 LEU C CD2 1 
ATOM   7882  N N   . ASP C 1 195 ? 94.042  120.899 95.722  1.00 47.87 ? 195 ASP C N   1 
ATOM   7883  C CA  . ASP C 1 195 ? 92.635  121.045 96.067  1.00 47.87 ? 195 ASP C CA  1 
ATOM   7884  C C   . ASP C 1 195 ? 92.438  120.228 97.327  1.00 47.87 ? 195 ASP C C   1 
ATOM   7885  O O   . ASP C 1 195 ? 92.405  118.998 97.268  1.00 47.87 ? 195 ASP C O   1 
ATOM   7886  C CB  . ASP C 1 195 ? 91.740  120.546 94.940  1.00 47.87 ? 195 ASP C CB  1 
ATOM   7887  C CG  . ASP C 1 195 ? 91.879  121.362 93.677  1.00 47.87 ? 195 ASP C CG  1 
ATOM   7888  O OD1 . ASP C 1 195 ? 92.177  122.571 93.764  1.00 47.87 ? 195 ASP C OD1 1 
ATOM   7889  O OD2 . ASP C 1 195 ? 91.689  120.790 92.585  1.00 47.87 ? 195 ASP C OD2 1 
ATOM   7890  N N   . MET C 1 196 ? 92.359  120.893 98.481  1.00 46.26 ? 196 MET C N   1 
ATOM   7891  C CA  . MET C 1 196 ? 92.271  120.161 99.740  1.00 46.26 ? 196 MET C CA  1 
ATOM   7892  C C   . MET C 1 196 ? 90.807  119.799 99.952  1.00 46.26 ? 196 MET C C   1 
ATOM   7893  O O   . MET C 1 196 ? 90.072  120.458 100.689 1.00 46.26 ? 196 MET C O   1 
ATOM   7894  C CB  . MET C 1 196 ? 92.815  120.987 100.896 1.00 46.26 ? 196 MET C CB  1 
ATOM   7895  C CG  . MET C 1 196 ? 94.294  121.243 100.874 1.00 46.26 ? 196 MET C CG  1 
ATOM   7896  S SD  . MET C 1 196 ? 95.227  119.724 100.876 1.00 46.26 ? 196 MET C SD  1 
ATOM   7897  C CE  . MET C 1 196 ? 96.839  120.338 101.326 1.00 46.26 ? 196 MET C CE  1 
ATOM   7898  N N   . GLN C 1 197 ? 90.373  118.745 99.269  1.00 45.56 ? 197 GLN C N   1 
ATOM   7899  C CA  . GLN C 1 197 ? 88.970  118.369 99.312  1.00 45.56 ? 197 GLN C CA  1 
ATOM   7900  C C   . GLN C 1 197 ? 88.496  118.206 100.743 1.00 45.56 ? 197 GLN C C   1 
ATOM   7901  O O   . GLN C 1 197 ? 89.255  117.804 101.625 1.00 45.56 ? 197 GLN C O   1 
ATOM   7902  C CB  . GLN C 1 197 ? 88.730  117.076 98.543  1.00 45.56 ? 197 GLN C CB  1 
ATOM   7903  C CG  . GLN C 1 197 ? 88.223  117.269 97.137  1.00 45.56 ? 197 GLN C CG  1 
ATOM   7904  C CD  . GLN C 1 197 ? 89.318  117.583 96.155  1.00 45.56 ? 197 GLN C CD  1 
ATOM   7905  O OE1 . GLN C 1 197 ? 90.491  117.365 96.429  1.00 45.56 ? 197 GLN C OE1 1 
ATOM   7906  N NE2 . GLN C 1 197 ? 88.940  118.100 94.996  1.00 45.56 ? 197 GLN C NE2 1 
ATOM   7907  N N   . ARG C 1 198 ? 87.228  118.553 100.971 1.00 50.20 ? 198 ARG C N   1 
ATOM   7908  C CA  . ARG C 1 198 ? 86.606  118.332 102.266 1.00 50.20 ? 198 ARG C CA  1 
ATOM   7909  C C   . ARG C 1 198 ? 86.483  116.851 102.579 1.00 50.20 ? 198 ARG C C   1 
ATOM   7910  O O   . ARG C 1 198 ? 86.221  116.487 103.729 1.00 50.20 ? 198 ARG C O   1 
ATOM   7911  C CB  . ARG C 1 198 ? 85.229  118.993 102.305 1.00 50.20 ? 198 ARG C CB  1 
ATOM   7912  C CG  . ARG C 1 198 ? 84.641  119.084 103.687 1.00 50.20 ? 198 ARG C CG  1 
ATOM   7913  C CD  . ARG C 1 198 ? 83.296  119.752 103.690 1.00 50.20 ? 198 ARG C CD  1 
ATOM   7914  N NE  . ARG C 1 198 ? 83.340  121.047 103.030 1.00 50.20 ? 198 ARG C NE  1 
ATOM   7915  C CZ  . ARG C 1 198 ? 82.333  121.908 103.025 1.00 50.20 ? 198 ARG C CZ  1 
ATOM   7916  N NH1 . ARG C 1 198 ? 81.219  121.626 103.682 1.00 50.20 ? 198 ARG C NH1 1 
ATOM   7917  N NH2 . ARG C 1 198 ? 82.451  123.064 102.391 1.00 50.20 ? 198 ARG C NH2 1 
ATOM   7918  N N   . SER C 1 199 ? 86.672  115.989 101.581 1.00 50.51 ? 199 SER C N   1 
ATOM   7919  C CA  . SER C 1 199 ? 86.684  114.547 101.781 1.00 50.51 ? 199 SER C CA  1 
ATOM   7920  C C   . SER C 1 199 ? 88.083  114.006 102.041 1.00 50.51 ? 199 SER C C   1 
ATOM   7921  O O   . SER C 1 199 ? 88.354  112.835 101.751 1.00 50.51 ? 199 SER C O   1 
ATOM   7922  C CB  . SER C 1 199 ? 86.056  113.857 100.574 1.00 50.51 ? 199 SER C CB  1 
ATOM   7923  O OG  . SER C 1 199 ? 84.713  114.274 100.412 1.00 50.51 ? 199 SER C OG  1 
ATOM   7924  N N   . ALA C 1 200 ? 88.982  114.844 102.552 1.00 44.78 ? 200 ALA C N   1 
ATOM   7925  C CA  . ALA C 1 200 ? 90.328  114.456 102.950 1.00 44.78 ? 200 ALA C CA  1 
ATOM   7926  C C   . ALA C 1 200 ? 91.158  113.957 101.778 1.00 44.78 ? 200 ALA C C   1 
ATOM   7927  O O   . ALA C 1 200 ? 92.316  113.569 101.956 1.00 44.78 ? 200 ALA C O   1 
ATOM   7928  C CB  . ALA C 1 200 ? 90.278  113.391 104.043 1.00 44.78 ? 200 ALA C CB  1 
ATOM   7929  N N   . ALA C 1 201 ? 90.592  113.986 100.579 1.00 46.34 ? 201 ALA C N   1 
ATOM   7930  C CA  . ALA C 1 201 ? 91.234  113.448 99.387  1.00 46.34 ? 201 ALA C CA  1 
ATOM   7931  C C   . ALA C 1 201 ? 91.795  114.601 98.563  1.00 46.34 ? 201 ALA C C   1 
ATOM   7932  O O   . ALA C 1 201 ? 91.180  115.041 97.595  1.00 46.34 ? 201 ALA C O   1 
ATOM   7933  C CB  . ALA C 1 201 ? 90.240  112.622 98.584  1.00 46.34 ? 201 ALA C CB  1 
ATOM   7934  N N   . CYS C 1 202 ? 92.980  115.070 98.933  1.00 46.41 ? 202 CYS C N   1 
ATOM   7935  C CA  . CYS C 1 202 ? 93.594  116.193 98.239  1.00 46.41 ? 202 CYS C CA  1 
ATOM   7936  C C   . CYS C 1 202 ? 93.945  115.817 96.806  1.00 46.41 ? 202 CYS C C   1 
ATOM   7937  O O   . CYS C 1 202 ? 94.369  114.694 96.532  1.00 46.41 ? 202 CYS C O   1 
ATOM   7938  C CB  . CYS C 1 202 ? 94.837  116.669 98.991  1.00 46.41 ? 202 CYS C CB  1 
ATOM   7939  S SG  . CYS C 1 202 ? 96.313  115.699 98.722  1.00 46.41 ? 202 CYS C SG  1 
ATOM   7940  N N   . THR C 1 203 ? 93.747  116.759 95.887  1.00 42.89 ? 203 THR C N   1 
ATOM   7941  C CA  . THR C 1 203 ? 93.956  116.515 94.465  1.00 42.89 ? 203 THR C CA  1 
ATOM   7942  C C   . THR C 1 203 ? 94.983  117.485 93.895  1.00 42.89 ? 203 THR C C   1 
ATOM   7943  O O   . THR C 1 203 ? 94.846  118.701 94.045  1.00 42.89 ? 203 THR C O   1 
ATOM   7944  C CB  . THR C 1 203 ? 92.642  116.629 93.699  1.00 42.89 ? 203 THR C CB  1 
ATOM   7945  O OG1 . THR C 1 203 ? 91.746  115.600 94.136  1.00 42.89 ? 203 THR C OG1 1 
ATOM   7946  C CG2 . THR C 1 203 ? 92.884  116.483 92.216  1.00 42.89 ? 203 THR C CG2 1 
ATOM   7947  N N   . LEU C 1 204 ? 95.990  116.942 93.221  1.00 41.57 ? 204 LEU C N   1 
ATOM   7948  C CA  . LEU C 1 204 ? 97.082  117.723 92.664  1.00 41.57 ? 204 LEU C CA  1 
ATOM   7949  C C   . LEU C 1 204 ? 96.729  118.279 91.285  1.00 41.57 ? 204 LEU C C   1 
ATOM   7950  O O   . LEU C 1 204 ? 95.992  117.665 90.511  1.00 41.57 ? 204 LEU C O   1 
ATOM   7951  C CB  . LEU C 1 204 ? 98.339  116.864 92.583  1.00 41.57 ? 204 LEU C CB  1 
ATOM   7952  C CG  . LEU C 1 204 ? 99.626  117.534 92.136  1.00 41.57 ? 204 LEU C CG  1 
ATOM   7953  C CD1 . LEU C 1 204 ? 99.824  118.788 92.920  1.00 41.57 ? 204 LEU C CD1 1 
ATOM   7954  C CD2 . LEU C 1 204 ? 100.786 116.612 92.359  1.00 41.57 ? 204 LEU C CD2 1 
ATOM   7955  N N   . LYS C 1 205 ? 97.256  119.469 90.995  1.00 45.51 ? 205 LYS C N   1 
ATOM   7956  C CA  . LYS C 1 205 ? 97.108  120.131 89.711  1.00 45.51 ? 205 LYS C CA  1 
ATOM   7957  C C   . LYS C 1 205 ? 98.458  120.689 89.316  1.00 45.51 ? 205 LYS C C   1 
ATOM   7958  O O   . LYS C 1 205 ? 99.151  121.265 90.154  1.00 45.51 ? 205 LYS C O   1 
ATOM   7959  C CB  . LYS C 1 205 ? 96.111  121.274 89.781  1.00 45.51 ? 205 LYS C CB  1 
ATOM   7960  C CG  . LYS C 1 205 ? 94.722  120.853 90.129  1.00 45.51 ? 205 LYS C CG  1 
ATOM   7961  C CD  . LYS C 1 205 ? 93.777  122.012 89.986  1.00 45.51 ? 205 LYS C CD  1 
ATOM   7962  C CE  . LYS C 1 205 ? 93.948  122.975 91.125  1.00 45.51 ? 205 LYS C CE  1 
ATOM   7963  N NZ  . LYS C 1 205 ? 92.955  124.072 91.045  1.00 45.51 ? 205 LYS C NZ  1 
ATOM   7964  N N   . THR C 1 206 ? 98.823  120.552 88.048  1.00 49.99 ? 206 THR C N   1 
ATOM   7965  C CA  . THR C 1 206 ? 100.140 120.966 87.601  1.00 49.99 ? 206 THR C CA  1 
ATOM   7966  C C   . THR C 1 206 ? 100.013 121.929 86.435  1.00 49.99 ? 206 THR C C   1 
ATOM   7967  O O   . THR C 1 206 ? 99.231  121.707 85.508  1.00 49.99 ? 206 THR C O   1 
ATOM   7968  C CB  . THR C 1 206 ? 100.992 119.765 87.188  1.00 49.99 ? 206 THR C CB  1 
ATOM   7969  O OG1 . THR C 1 206 ? 100.985 118.794 88.236  1.00 49.99 ? 206 THR C OG1 1 
ATOM   7970  C CG2 . THR C 1 206 ? 102.419 120.185 86.944  1.00 49.99 ? 206 THR C CG2 1 
ATOM   7971  N N   . ALA C 1 207 ? 100.800 122.992 86.485  1.00 51.96 ? 207 ALA C N   1 
ATOM   7972  C CA  . ALA C 1 207 ? 100.866 123.965 85.412  1.00 51.96 ? 207 ALA C CA  1 
ATOM   7973  C C   . ALA C 1 207 ? 102.291 124.063 84.902  1.00 51.96 ? 207 ALA C C   1 
ATOM   7974  O O   . ALA C 1 207 ? 103.244 124.078 85.691  1.00 51.96 ? 207 ALA C O   1 
ATOM   7975  C CB  . ALA C 1 207 ? 100.397 125.330 85.876  1.00 51.96 ? 207 ALA C CB  1 
ATOM   7976  N N   . PHE C 1 208 ? 102.417 124.141 83.582  1.00 52.68 ? 208 PHE C N   1 
ATOM   7977  C CA  . PHE C 1 208 ? 103.698 124.249 82.893  1.00 52.68 ? 208 PHE C CA  1 
ATOM   7978  C C   . PHE C 1 208 ? 103.763 125.573 82.146  1.00 52.68 ? 208 PHE C C   1 
ATOM   7979  O O   . PHE C 1 208 ? 102.971 125.790 81.205  1.00 52.68 ? 208 PHE C O   1 
ATOM   7980  C CB  . PHE C 1 208 ? 103.885 123.087 81.922  1.00 52.68 ? 208 PHE C CB  1 
ATOM   7981  C CG  . PHE C 1 208 ? 104.289 121.790 82.573  1.00 52.68 ? 208 PHE C CG  1 
ATOM   7982  C CD1 . PHE C 1 208 ? 105.435 121.705 83.337  1.00 52.68 ? 208 PHE C CD1 1 
ATOM   7983  C CD2 . PHE C 1 208 ? 103.537 120.648 82.388  1.00 52.68 ? 208 PHE C CD2 1 
ATOM   7984  C CE1 . PHE C 1 208 ? 105.803 120.510 83.920  1.00 52.68 ? 208 PHE C CE1 1 
ATOM   7985  C CE2 . PHE C 1 208 ? 103.904 119.458 82.971  1.00 52.68 ? 208 PHE C CE2 1 
ATOM   7986  C CZ  . PHE C 1 208 ? 105.035 119.390 83.734  1.00 52.68 ? 208 PHE C CZ  1 
ATOM   7987  N N   . PRO C 1 209 ? 104.625 126.498 82.555  1.00 55.46 ? 209 PRO C N   1 
ATOM   7988  C CA  . PRO C 1 209 ? 104.957 127.638 81.717  1.00 55.46 ? 209 PRO C CA  1 
ATOM   7989  C C   . PRO C 1 209 ? 106.118 127.310 80.806  1.00 55.46 ? 209 PRO C C   1 
ATOM   7990  O O   . PRO C 1 209 ? 107.210 126.955 81.274  1.00 55.46 ? 209 PRO C O   1 
ATOM   7991  C CB  . PRO C 1 209 ? 105.342 128.726 82.731  1.00 55.46 ? 209 PRO C CB  1 
ATOM   7992  C CG  . PRO C 1 209 ? 105.092 128.149 84.069  1.00 55.46 ? 209 PRO C CG  1 
ATOM   7993  C CD  . PRO C 1 209 ? 105.149 126.682 83.911  1.00 55.46 ? 209 PRO C CD  1 
ATOM   7994  N N   . PRO C 1 210 ? 105.932 127.431 79.501  1.00 59.99 ? 210 PRO C N   1 
ATOM   7995  C CA  . PRO C 1 210 ? 106.956 126.996 78.551  1.00 59.99 ? 210 PRO C CA  1 
ATOM   7996  C C   . PRO C 1 210 ? 108.027 128.030 78.260  1.00 59.99 ? 210 PRO C C   1 
ATOM   7997  O O   . PRO C 1 210 ? 108.694 127.922 77.230  1.00 59.99 ? 210 PRO C O   1 
ATOM   7998  C CB  . PRO C 1 210 ? 106.141 126.701 77.288  1.00 59.99 ? 210 PRO C CB  1 
ATOM   7999  C CG  . PRO C 1 210 ? 104.733 126.663 77.726  1.00 59.99 ? 210 PRO C CG  1 
ATOM   8000  C CD  . PRO C 1 210 ? 104.638 127.613 78.845  1.00 59.99 ? 210 PRO C CD  1 
ATOM   8001  N N   . LEU C 1 211 ? 108.186 129.035 79.118  1.00 60.81 ? 211 LEU C N   1 
ATOM   8002  C CA  . LEU C 1 211 ? 109.080 130.142 78.793  1.00 60.81 ? 211 LEU C CA  1 
ATOM   8003  C C   . LEU C 1 211 ? 110.505 129.662 78.546  1.00 60.81 ? 211 LEU C C   1 
ATOM   8004  O O   . LEU C 1 211 ? 111.135 130.054 77.559  1.00 60.81 ? 211 LEU C O   1 
ATOM   8005  C CB  . LEU C 1 211 ? 109.053 131.187 79.902  1.00 60.81 ? 211 LEU C CB  1 
ATOM   8006  C CG  . LEU C 1 211 ? 109.827 132.440 79.511  1.00 60.81 ? 211 LEU C CG  1 
ATOM   8007  C CD1 . LEU C 1 211 ? 109.151 133.099 78.336  1.00 60.81 ? 211 LEU C CD1 1 
ATOM   8008  C CD2 . LEU C 1 211 ? 109.937 133.392 80.674  1.00 60.81 ? 211 LEU C CD2 1 
ATOM   8009  N N   . LEU C 1 212 ? 111.032 128.808 79.424  1.00 60.94 ? 212 LEU C N   1 
ATOM   8010  C CA  . LEU C 1 212 ? 112.373 128.279 79.201  1.00 60.94 ? 212 LEU C CA  1 
ATOM   8011  C C   . LEU C 1 212 ? 112.425 127.395 77.963  1.00 60.94 ? 212 LEU C C   1 
ATOM   8012  O O   . LEU C 1 212 ? 113.409 127.427 77.216  1.00 60.94 ? 212 LEU C O   1 
ATOM   8013  C CB  . LEU C 1 212 ? 112.842 127.492 80.418  1.00 60.94 ? 212 LEU C CB  1 
ATOM   8014  C CG  . LEU C 1 212 ? 112.750 128.165 81.781  1.00 60.94 ? 212 LEU C CG  1 
ATOM   8015  C CD1 . LEU C 1 212 ? 112.926 127.136 82.860  1.00 60.94 ? 212 LEU C CD1 1 
ATOM   8016  C CD2 . LEU C 1 212 ? 113.805 129.223 81.905  1.00 60.94 ? 212 LEU C CD2 1 
ATOM   8017  N N   . ARG C 1 213 ? 111.383 126.598 77.733  1.00 62.21 ? 213 ARG C N   1 
ATOM   8018  C CA  . ARG C 1 213 ? 111.326 125.778 76.528  1.00 62.21 ? 213 ARG C CA  1 
ATOM   8019  C C   . ARG C 1 213 ? 111.329 126.642 75.278  1.00 62.21 ? 213 ARG C C   1 
ATOM   8020  O O   . ARG C 1 213 ? 112.191 126.493 74.405  1.00 62.21 ? 213 ARG C O   1 
ATOM   8021  C CB  . ARG C 1 213 ? 110.081 124.901 76.550  1.00 62.21 ? 213 ARG C CB  1 
ATOM   8022  C CG  . ARG C 1 213 ? 109.808 124.215 75.242  1.00 62.21 ? 213 ARG C CG  1 
ATOM   8023  C CD  . ARG C 1 213 ? 110.888 123.212 74.942  1.00 62.21 ? 213 ARG C CD  1 
ATOM   8024  N NE  . ARG C 1 213 ? 110.773 122.032 75.786  1.00 62.21 ? 213 ARG C NE  1 
ATOM   8025  C CZ  . ARG C 1 213 ? 111.751 121.157 75.985  1.00 62.21 ? 213 ARG C CZ  1 
ATOM   8026  N NH1 . ARG C 1 213 ? 112.928 121.331 75.403  1.00 62.21 ? 213 ARG C NH1 1 
ATOM   8027  N NH2 . ARG C 1 213 ? 111.551 120.110 76.769  1.00 62.21 ? 213 ARG C NH2 1 
ATOM   8028  N N   . SER C 1 214 ? 110.356 127.545 75.171  1.00 63.93 ? 214 SER C N   1 
ATOM   8029  C CA  . SER C 1 214 ? 110.279 128.425 74.016  1.00 63.93 ? 214 SER C CA  1 
ATOM   8030  C C   . SER C 1 214 ? 111.529 129.271 73.879  1.00 63.93 ? 214 SER C C   1 
ATOM   8031  O O   . SER C 1 214 ? 111.832 129.773 72.793  1.00 63.93 ? 214 SER C O   1 
ATOM   8032  C CB  . SER C 1 214 ? 109.052 129.316 74.129  1.00 63.93 ? 214 SER C CB  1 
ATOM   8033  O OG  . SER C 1 214 ? 109.035 129.973 75.379  1.00 63.93 ? 214 SER C OG  1 
ATOM   8034  N N   . THR C 1 215 ? 112.267 129.451 74.968  1.00 61.91 ? 215 THR C N   1 
ATOM   8035  C CA  . THR C 1 215 ? 113.494 130.225 74.882  1.00 61.91 ? 215 THR C CA  1 
ATOM   8036  C C   . THR C 1 215 ? 114.612 129.409 74.256  1.00 61.91 ? 215 THR C C   1 
ATOM   8037  O O   . THR C 1 215 ? 115.195 129.814 73.245  1.00 61.91 ? 215 THR C O   1 
ATOM   8038  C CB  . THR C 1 215 ? 113.895 130.723 76.262  1.00 61.91 ? 215 THR C CB  1 
ATOM   8039  O OG1 . THR C 1 215 ? 112.956 131.709 76.695  1.00 61.91 ? 215 THR C OG1 1 
ATOM   8040  C CG2 . THR C 1 215 ? 115.265 131.344 76.211  1.00 61.91 ? 215 THR C CG2 1 
ATOM   8041  N N   . ILE C 1 216 ? 114.928 128.252 74.839  1.00 64.81 ? 216 ILE C N   1 
ATOM   8042  C CA  . ILE C 1 216 ? 116.037 127.456 74.320  1.00 64.81 ? 216 ILE C CA  1 
ATOM   8043  C C   . ILE C 1 216 ? 115.741 126.989 72.904  1.00 64.81 ? 216 ILE C C   1 
ATOM   8044  O O   . ILE C 1 216 ? 116.611 127.034 72.028  1.00 64.81 ? 216 ILE C O   1 
ATOM   8045  C CB  . ILE C 1 216 ? 116.350 126.271 75.250  1.00 64.81 ? 216 ILE C CB  1 
ATOM   8046  C CG1 . ILE C 1 216 ? 115.078 125.492 75.587  1.00 64.81 ? 216 ILE C CG1 1 
ATOM   8047  C CG2 . ILE C 1 216 ? 117.048 126.751 76.505  1.00 64.81 ? 216 ILE C CG2 1 
ATOM   8048  C CD1 . ILE C 1 216 ? 115.293 124.362 76.556  1.00 64.81 ? 216 ILE C CD1 1 
ATOM   8049  N N   . MET C 1 217 ? 114.514 126.547 72.649  1.00 67.51 ? 217 MET C N   1 
ATOM   8050  C CA  . MET C 1 217 ? 114.125 126.188 71.296  1.00 67.51 ? 217 MET C CA  1 
ATOM   8051  C C   . MET C 1 217 ? 113.940 127.404 70.407  1.00 67.51 ? 217 MET C C   1 
ATOM   8052  O O   . MET C 1 217 ? 113.824 127.245 69.189  1.00 67.51 ? 217 MET C O   1 
ATOM   8053  C CB  . MET C 1 217 ? 112.842 125.361 71.320  1.00 67.51 ? 217 MET C CB  1 
ATOM   8054  C CG  . MET C 1 217 ? 113.010 124.015 71.993  1.00 67.51 ? 217 MET C CG  1 
ATOM   8055  S SD  . MET C 1 217 ? 111.757 122.824 71.500  1.00 67.51 ? 217 MET C SD  1 
ATOM   8056  C CE  . MET C 1 217 ? 111.863 122.944 69.720  1.00 67.51 ? 217 MET C CE  1 
ATOM   8057  N N   . ASN C 1 218 ? 113.909 128.602 70.985  1.00 70.06 ? 218 ASN C N   1 
ATOM   8058  C CA  . ASN C 1 218 ? 113.810 129.847 70.228  1.00 70.06 ? 218 ASN C CA  1 
ATOM   8059  C C   . ASN C 1 218 ? 112.563 129.867 69.352  1.00 70.06 ? 218 ASN C C   1 
ATOM   8060  O O   . ASN C 1 218 ? 112.564 130.423 68.254  1.00 70.06 ? 218 ASN C O   1 
ATOM   8061  C CB  . ASN C 1 218 ? 115.067 130.084 69.391  1.00 70.06 ? 218 ASN C CB  1 
ATOM   8062  C CG  . ASN C 1 218 ? 116.291 130.345 70.243  1.00 70.06 ? 218 ASN C CG  1 
ATOM   8063  O OD1 . ASN C 1 218 ? 116.659 131.493 70.484  1.00 70.06 ? 218 ASN C OD1 1 
ATOM   8064  N ND2 . ASN C 1 218 ? 116.928 129.276 70.706  1.00 70.06 ? 218 ASN C ND2 1 
ATOM   8065  N N   . THR C 1 219 ? 111.490 129.258 69.838  1.00 69.02 ? 219 THR C N   1 
ATOM   8066  C CA  . THR C 1 219 ? 110.234 129.212 69.114  1.00 69.02 ? 219 THR C CA  1 
ATOM   8067  C C   . THR C 1 219 ? 109.151 129.925 69.907  1.00 69.02 ? 219 THR C C   1 
ATOM   8068  O O   . THR C 1 219 ? 109.330 130.270 71.076  1.00 69.02 ? 219 THR C O   1 
ATOM   8069  C CB  . THR C 1 219 ? 109.807 127.776 68.832  1.00 69.02 ? 219 THR C CB  1 
ATOM   8070  O OG1 . THR C 1 219 ? 109.632 127.090 70.073  1.00 69.02 ? 219 THR C OG1 1 
ATOM   8071  C CG2 . THR C 1 219 ? 110.868 127.065 68.018  1.00 69.02 ? 219 THR C CG2 1 
ATOM   8072  N N   . SER C 1 220 ? 108.017 130.142 69.253  1.00 70.76 ? 220 SER C N   1 
ATOM   8073  C CA  . SER C 1 220 ? 106.946 130.916 69.859  1.00 70.76 ? 220 SER C CA  1 
ATOM   8074  C C   . SER C 1 220 ? 106.184 130.085 70.879  1.00 70.76 ? 220 SER C C   1 
ATOM   8075  O O   . SER C 1 220 ? 105.951 128.888 70.685  1.00 70.76 ? 220 SER C O   1 
ATOM   8076  C CB  . SER C 1 220 ? 105.994 131.432 68.785  1.00 70.76 ? 220 SER C CB  1 
ATOM   8077  O OG  . SER C 1 220 ? 106.547 132.555 68.128  1.00 70.76 ? 220 SER C OG  1 
ATOM   8078  N N   . MET C 1 221 ? 105.803 130.740 71.977  1.00 71.65 ? 221 MET C N   1 
ATOM   8079  C CA  . MET C 1 221 ? 105.044 130.080 73.031  1.00 71.65 ? 221 MET C CA  1 
ATOM   8080  C C   . MET C 1 221 ? 103.800 129.416 72.465  1.00 71.65 ? 221 MET C C   1 
ATOM   8081  O O   . MET C 1 221 ? 103.504 128.249 72.758  1.00 71.65 ? 221 MET C O   1 
ATOM   8082  C CB  . MET C 1 221 ? 104.652 131.099 74.098  1.00 71.65 ? 221 MET C CB  1 
ATOM   8083  C CG  . MET C 1 221 ? 105.720 132.135 74.431  1.00 71.65 ? 221 MET C CG  1 
ATOM   8084  S SD  . MET C 1 221 ? 107.000 131.554 75.553  1.00 71.65 ? 221 MET C SD  1 
ATOM   8085  C CE  . MET C 1 221 ? 106.053 131.240 77.033  1.00 71.65 ? 221 MET C CE  1 
ATOM   8086  N N   . VAL C 1 222 ? 103.058 130.165 71.653  1.00 72.58 ? 222 VAL C N   1 
ATOM   8087  C CA  . VAL C 1 222 ? 101.838 129.650 71.041  1.00 72.58 ? 222 VAL C CA  1 
ATOM   8088  C C   . VAL C 1 222 ? 102.110 128.310 70.378  1.00 72.58 ? 222 VAL C C   1 
ATOM   8089  O O   . VAL C 1 222 ? 101.388 127.323 70.585  1.00 72.58 ? 222 VAL C O   1 
ATOM   8090  C CB  . VAL C 1 222 ? 101.294 130.674 70.029  1.00 72.58 ? 222 VAL C CB  1 
ATOM   8091  C CG1 . VAL C 1 222 ? 99.869  130.339 69.638  1.00 72.58 ? 222 VAL C CG1 1 
ATOM   8092  C CG2 . VAL C 1 222 ? 101.399 132.080 70.595  1.00 72.58 ? 222 VAL C CG2 1 
ATOM   8093  N N   . ASP C 1 223 ? 103.186 128.251 69.596  1.00 73.91 ? 223 ASP C N   1 
ATOM   8094  C CA  . ASP C 1 223 ? 103.432 127.085 68.762  1.00 73.91 ? 223 ASP C CA  1 
ATOM   8095  C C   . ASP C 1 223 ? 103.755 125.856 69.594  1.00 73.91 ? 223 ASP C C   1 
ATOM   8096  O O   . ASP C 1 223 ? 103.169 124.791 69.379  1.00 73.91 ? 223 ASP C O   1 
ATOM   8097  C CB  . ASP C 1 223 ? 104.547 127.377 67.765  1.00 73.91 ? 223 ASP C CB  1 
ATOM   8098  C CG  . ASP C 1 223 ? 104.110 128.336 66.686  1.00 73.91 ? 223 ASP C CG  1 
ATOM   8099  O OD1 . ASP C 1 223 ? 102.908 128.329 66.349  1.00 73.91 ? 223 ASP C OD1 1 
ATOM   8100  O OD2 . ASP C 1 223 ? 104.964 129.088 66.175  1.00 73.91 ? 223 ASP C OD2 1 
ATOM   8101  N N   . ILE C 1 224 ? 104.690 125.963 70.538  1.00 68.49 ? 224 ILE C N   1 
ATOM   8102  C CA  . ILE C 1 224 ? 105.029 124.774 71.311  1.00 68.49 ? 224 ILE C CA  1 
ATOM   8103  C C   . ILE C 1 224 ? 103.840 124.326 72.144  1.00 68.49 ? 224 ILE C C   1 
ATOM   8104  O O   . ILE C 1 224 ? 103.545 123.128 72.230  1.00 68.49 ? 224 ILE C O   1 
ATOM   8105  C CB  . ILE C 1 224 ? 106.275 125.006 72.178  1.00 68.49 ? 224 ILE C CB  1 
ATOM   8106  C CG1 . ILE C 1 224 ? 106.096 126.201 73.085  1.00 68.49 ? 224 ILE C CG1 1 
ATOM   8107  C CG2 . ILE C 1 224 ? 107.478 125.229 71.312  1.00 68.49 ? 224 ILE C CG2 1 
ATOM   8108  C CD1 . ILE C 1 224 ? 107.255 126.388 73.968  1.00 68.49 ? 224 ILE C CD1 1 
ATOM   8109  N N   . MET C 1 225 ? 103.118 125.273 72.744  1.00 70.10 ? 225 MET C N   1 
ATOM   8110  C CA  . MET C 1 225 ? 101.963 124.900 73.550  1.00 70.10 ? 225 MET C CA  1 
ATOM   8111  C C   . MET C 1 225 ? 100.953 124.115 72.728  1.00 70.10 ? 225 MET C C   1 
ATOM   8112  O O   . MET C 1 225 ? 100.523 123.019 73.117  1.00 70.10 ? 225 MET C O   1 
ATOM   8113  C CB  . MET C 1 225 ? 101.315 126.147 74.143  1.00 70.10 ? 225 MET C CB  1 
ATOM   8114  C CG  . MET C 1 225 ? 102.077 126.757 75.303  1.00 70.10 ? 225 MET C CG  1 
ATOM   8115  S SD  . MET C 1 225 ? 101.208 128.154 76.031  1.00 70.10 ? 225 MET C SD  1 
ATOM   8116  C CE  . MET C 1 225 ? 102.576 129.205 76.497  1.00 70.10 ? 225 MET C CE  1 
ATOM   8117  N N   . PHE C 1 226 ? 100.578 124.648 71.569  1.00 71.25 ? 226 PHE C N   1 
ATOM   8118  C CA  . PHE C 1 226 ? 99.508  124.012 70.816  1.00 71.25 ? 226 PHE C CA  1 
ATOM   8119  C C   . PHE C 1 226 ? 99.977  122.775 70.070  1.00 71.25 ? 226 PHE C C   1 
ATOM   8120  O O   . PHE C 1 226 ? 99.188  121.854 69.858  1.00 71.25 ? 226 PHE C O   1 
ATOM   8121  C CB  . PHE C 1 226 ? 98.876  125.028 69.882  1.00 71.25 ? 226 PHE C CB  1 
ATOM   8122  C CG  . PHE C 1 226 ? 98.037  126.021 70.602  1.00 71.25 ? 226 PHE C CG  1 
ATOM   8123  C CD1 . PHE C 1 226 ? 96.904  125.611 71.277  1.00 71.25 ? 226 PHE C CD1 1 
ATOM   8124  C CD2 . PHE C 1 226 ? 98.397  127.350 70.652  1.00 71.25 ? 226 PHE C CD2 1 
ATOM   8125  C CE1 . PHE C 1 226 ? 96.131  126.513 71.959  1.00 71.25 ? 226 PHE C CE1 1 
ATOM   8126  C CE2 . PHE C 1 226 ? 97.627  128.259 71.332  1.00 71.25 ? 226 PHE C CE2 1 
ATOM   8127  C CZ  . PHE C 1 226 ? 96.493  127.840 71.988  1.00 71.25 ? 226 PHE C CZ  1 
ATOM   8128  N N   . ASP C 1 227 ? 101.256 122.693 69.722  1.00 69.47 ? 227 ASP C N   1 
ATOM   8129  C CA  . ASP C 1 227 ? 101.760 121.456 69.147  1.00 69.47 ? 227 ASP C CA  1 
ATOM   8130  C C   . ASP C 1 227 ? 101.795 120.348 70.188  1.00 69.47 ? 227 ASP C C   1 
ATOM   8131  O O   . ASP C 1 227 ? 101.527 119.184 69.871  1.00 69.47 ? 227 ASP C O   1 
ATOM   8132  C CB  . ASP C 1 227 ? 103.142 121.686 68.548  1.00 69.47 ? 227 ASP C CB  1 
ATOM   8133  C CG  . ASP C 1 227 ? 103.092 122.527 67.290  1.00 69.47 ? 227 ASP C CG  1 
ATOM   8134  O OD1 . ASP C 1 227 ? 101.998 123.022 66.946  1.00 69.47 ? 227 ASP C OD1 1 
ATOM   8135  O OD2 . ASP C 1 227 ? 104.145 122.692 66.643  1.00 69.47 ? 227 ASP C OD2 1 
ATOM   8136  N N   . ALA C 1 228 ? 102.112 120.688 71.438  1.00 66.02 ? 228 ALA C N   1 
ATOM   8137  C CA  . ALA C 1 228 ? 102.039 119.696 72.502  1.00 66.02 ? 228 ALA C CA  1 
ATOM   8138  C C   . ALA C 1 228 ? 100.611 119.210 72.694  1.00 66.02 ? 228 ALA C C   1 
ATOM   8139  O O   . ALA C 1 228 ? 100.354 118.000 72.758  1.00 66.02 ? 228 ALA C O   1 
ATOM   8140  C CB  . ALA C 1 228 ? 102.595 120.278 73.797  1.00 66.02 ? 228 ALA C CB  1 
ATOM   8141  N N   . VAL C 1 229 ? 99.657  120.138 72.781  1.00 69.81 ? 229 VAL C N   1 
ATOM   8142  C CA  . VAL C 1 229 ? 98.279  119.687 72.958  1.00 69.81 ? 229 VAL C CA  1 
ATOM   8143  C C   . VAL C 1 229 ? 97.817  118.880 71.749  1.00 69.81 ? 229 VAL C C   1 
ATOM   8144  O O   . VAL C 1 229 ? 97.023  117.943 71.887  1.00 69.81 ? 229 VAL C O   1 
ATOM   8145  C CB  . VAL C 1 229 ? 97.333  120.868 73.261  1.00 69.81 ? 229 VAL C CB  1 
ATOM   8146  C CG1 . VAL C 1 229 ? 97.050  121.682 72.026  1.00 69.81 ? 229 VAL C CG1 1 
ATOM   8147  C CG2 . VAL C 1 229 ? 96.035  120.349 73.842  1.00 69.81 ? 229 VAL C CG2 1 
ATOM   8148  N N   . GLU C 1 230 ? 98.340  119.181 70.559  1.00 72.66 ? 230 GLU C N   1 
ATOM   8149  C CA  . GLU C 1 230 ? 97.935  118.443 69.368  1.00 72.66 ? 230 GLU C CA  1 
ATOM   8150  C C   . GLU C 1 230 ? 98.479  117.022 69.385  1.00 72.66 ? 230 GLU C C   1 
ATOM   8151  O O   . GLU C 1 230 ? 97.761  116.062 69.066  1.00 72.66 ? 230 GLU C O   1 
ATOM   8152  C CB  . GLU C 1 230 ? 98.410  119.177 68.120  1.00 72.66 ? 230 GLU C CB  1 
ATOM   8153  C CG  . GLU C 1 230 ? 98.184  118.404 66.852  1.00 72.66 ? 230 GLU C CG  1 
ATOM   8154  C CD  . GLU C 1 230 ? 96.728  118.071 66.651  1.00 72.66 ? 230 GLU C CD  1 
ATOM   8155  O OE1 . GLU C 1 230 ? 95.878  118.929 66.959  1.00 72.66 ? 230 GLU C OE1 1 
ATOM   8156  O OE2 . GLU C 1 230 ? 96.426  116.953 66.192  1.00 72.66 ? 230 GLU C OE2 1 
ATOM   8157  N N   . SER C 1 231 ? 99.758  116.869 69.729  1.00 67.92 ? 231 SER C N   1 
ATOM   8158  C CA  . SER C 1 231 ? 100.320 115.529 69.822  1.00 67.92 ? 231 SER C CA  1 
ATOM   8159  C C   . SER C 1 231 ? 99.589  114.718 70.876  1.00 67.92 ? 231 SER C C   1 
ATOM   8160  O O   . SER C 1 231 ? 99.372  113.516 70.701  1.00 67.92 ? 231 SER C O   1 
ATOM   8161  C CB  . SER C 1 231 ? 101.813 115.583 70.133  1.00 67.92 ? 231 SER C CB  1 
ATOM   8162  O OG  . SER C 1 231 ? 102.044 115.958 71.472  1.00 67.92 ? 231 SER C OG  1 
ATOM   8163  N N   . PHE C 1 232 ? 99.183  115.358 71.973  1.00 67.44 ? 232 PHE C N   1 
ATOM   8164  C CA  . PHE C 1 232 ? 98.404  114.628 72.966  1.00 67.44 ? 232 PHE C CA  1 
ATOM   8165  C C   . PHE C 1 232 ? 97.044  114.240 72.414  1.00 67.44 ? 232 PHE C C   1 
ATOM   8166  O O   . PHE C 1 232 ? 96.541  113.148 72.694  1.00 67.44 ? 232 PHE C O   1 
ATOM   8167  C CB  . PHE C 1 232 ? 98.237  115.450 74.238  1.00 67.44 ? 232 PHE C CB  1 
ATOM   8168  C CG  . PHE C 1 232 ? 97.571  114.696 75.350  1.00 67.44 ? 232 PHE C CG  1 
ATOM   8169  C CD1 . PHE C 1 232 ? 98.252  113.714 76.040  1.00 67.44 ? 232 PHE C CD1 1 
ATOM   8170  C CD2 . PHE C 1 232 ? 96.260  114.951 75.688  1.00 67.44 ? 232 PHE C CD2 1 
ATOM   8171  C CE1 . PHE C 1 232 ? 97.643  113.013 77.049  1.00 67.44 ? 232 PHE C CE1 1 
ATOM   8172  C CE2 . PHE C 1 232 ? 95.649  114.250 76.696  1.00 67.44 ? 232 PHE C CE2 1 
ATOM   8173  C CZ  . PHE C 1 232 ? 96.342  113.281 77.376  1.00 67.44 ? 232 PHE C CZ  1 
ATOM   8174  N N   . ARG C 1 233 ? 96.429  115.128 71.637  1.00 75.61 ? 233 ARG C N   1 
ATOM   8175  C CA  . ARG C 1 233 ? 95.135  114.818 71.044  1.00 75.61 ? 233 ARG C CA  1 
ATOM   8176  C C   . ARG C 1 233 ? 95.217  113.588 70.156  1.00 75.61 ? 233 ARG C C   1 
ATOM   8177  O O   . ARG C 1 233 ? 94.317  112.742 70.165  1.00 75.61 ? 233 ARG C O   1 
ATOM   8178  C CB  . ARG C 1 233 ? 94.634  116.009 70.242  1.00 75.61 ? 233 ARG C CB  1 
ATOM   8179  C CG  . ARG C 1 233 ? 94.053  117.101 71.083  1.00 75.61 ? 233 ARG C CG  1 
ATOM   8180  C CD  . ARG C 1 233 ? 93.302  118.056 70.201  1.00 75.61 ? 233 ARG C CD  1 
ATOM   8181  N NE  . ARG C 1 233 ? 92.616  117.351 69.129  1.00 75.61 ? 233 ARG C NE  1 
ATOM   8182  C CZ  . ARG C 1 233 ? 91.916  117.951 68.177  1.00 75.61 ? 233 ARG C CZ  1 
ATOM   8183  N NH1 . ARG C 1 233 ? 91.811  119.270 68.166  1.00 75.61 ? 233 ARG C NH1 1 
ATOM   8184  N NH2 . ARG C 1 233 ? 91.322  117.231 67.238  1.00 75.61 ? 233 ARG C NH2 1 
ATOM   8185  N N   . LYS C 1 234 ? 96.289  113.472 69.380  1.00 75.09 ? 234 LYS C N   1 
ATOM   8186  C CA  . LYS C 1 234 ? 96.376  112.342 68.462  1.00 75.09 ? 234 LYS C CA  1 
ATOM   8187  C C   . LYS C 1 234 ? 96.800  111.071 69.185  1.00 75.09 ? 234 LYS C C   1 
ATOM   8188  O O   . LYS C 1 234 ? 96.220  110.004 68.968  1.00 75.09 ? 234 LYS C O   1 
ATOM   8189  C CB  . LYS C 1 234 ? 97.323  112.662 67.311  1.00 75.09 ? 234 LYS C CB  1 
ATOM   8190  C CG  . LYS C 1 234 ? 96.888  113.859 66.476  1.00 75.09 ? 234 LYS C CG  1 
ATOM   8191  C CD  . LYS C 1 234 ? 95.592  113.600 65.702  1.00 75.09 ? 234 LYS C CD  1 
ATOM   8192  C CE  . LYS C 1 234 ? 94.369  114.195 66.409  1.00 75.09 ? 234 LYS C CE  1 
ATOM   8193  N NZ  . LYS C 1 234 ? 93.119  114.044 65.618  1.00 75.09 ? 234 LYS C NZ  1 
ATOM   8194  N N   . GLN C 1 235 ? 97.802  111.165 70.058  1.00 72.89 ? 235 GLN C N   1 
ATOM   8195  C CA  . GLN C 1 235 ? 98.249  110.004 70.816  1.00 72.89 ? 235 GLN C CA  1 
ATOM   8196  C C   . GLN C 1 235 ? 97.158  109.451 71.721  1.00 72.89 ? 235 GLN C C   1 
ATOM   8197  O O   . GLN C 1 235 ? 97.131  108.246 71.976  1.00 72.89 ? 235 GLN C O   1 
ATOM   8198  C CB  . GLN C 1 235 ? 99.483  110.381 71.640  1.00 72.89 ? 235 GLN C CB  1 
ATOM   8199  C CG  . GLN C 1 235 ? 100.039 109.283 72.517  1.00 72.89 ? 235 GLN C CG  1 
ATOM   8200  C CD  . GLN C 1 235 ? 99.333  109.214 73.847  1.00 72.89 ? 235 GLN C CD  1 
ATOM   8201  O OE1 . GLN C 1 235 ? 98.718  110.183 74.279  1.00 72.89 ? 235 GLN C OE1 1 
ATOM   8202  N NE2 . GLN C 1 235 ? 99.402  108.063 74.497  1.00 72.89 ? 235 GLN C NE2 1 
ATOM   8203  N N   . SER C 1 236 ? 96.261  110.299 72.209  1.00 73.78 ? 236 SER C N   1 
ATOM   8204  C CA  . SER C 1 236 ? 95.225  109.880 73.140  1.00 73.78 ? 236 SER C CA  1 
ATOM   8205  C C   . SER C 1 236 ? 93.871  109.705 72.484  1.00 73.78 ? 236 SER C C   1 
ATOM   8206  O O   . SER C 1 236 ? 93.026  108.980 73.018  1.00 73.78 ? 236 SER C O   1 
ATOM   8207  C CB  . SER C 1 236 ? 95.093  110.902 74.271  1.00 73.78 ? 236 SER C CB  1 
ATOM   8208  O OG  . SER C 1 236 ? 94.820  112.192 73.757  1.00 73.78 ? 236 SER C OG  1 
ATOM   8209  N N   . GLY C 1 237 ? 93.641  110.359 71.350  1.00 78.35 ? 237 GLY C N   1 
ATOM   8210  C CA  . GLY C 1 237 ? 92.347  110.335 70.724  1.00 78.35 ? 237 GLY C CA  1 
ATOM   8211  C C   . GLY C 1 237 ? 91.334  111.275 71.327  1.00 78.35 ? 237 GLY C C   1 
ATOM   8212  O O   . GLY C 1 237 ? 90.283  111.500 70.715  1.00 78.35 ? 237 GLY C O   1 
ATOM   8213  N N   . LEU C 1 238 ? 91.606  111.837 72.498  1.00 77.75 ? 238 LEU C N   1 
ATOM   8214  C CA  . LEU C 1 238 ? 90.623  112.689 73.141  1.00 77.75 ? 238 LEU C CA  1 
ATOM   8215  C C   . LEU C 1 238 ? 90.560  114.048 72.450  1.00 77.75 ? 238 LEU C C   1 
ATOM   8216  O O   . LEU C 1 238 ? 91.476  114.456 71.733  1.00 77.75 ? 238 LEU C O   1 
ATOM   8217  C CB  . LEU C 1 238 ? 90.938  112.851 74.627  1.00 77.75 ? 238 LEU C CB  1 
ATOM   8218  C CG  . LEU C 1 238 ? 90.628  111.631 75.497  1.00 77.75 ? 238 LEU C CG  1 
ATOM   8219  C CD1 . LEU C 1 238 ? 91.799  110.676 75.540  1.00 77.75 ? 238 LEU C CD1 1 
ATOM   8220  C CD2 . LEU C 1 238 ? 90.236  112.043 76.894  1.00 77.75 ? 238 LEU C CD2 1 
ATOM   8221  N N   . TYR C 1 239 ? 89.458  114.753 72.689  1.00 82.90 ? 239 TYR C N   1 
ATOM   8222  C CA  . TYR C 1 239 ? 89.090  115.942 71.933  1.00 82.90 ? 239 TYR C CA  1 
ATOM   8223  C C   . TYR C 1 239 ? 89.377  117.186 72.762  1.00 82.90 ? 239 TYR C C   1 
ATOM   8224  O O   . TYR C 1 239 ? 88.657  117.469 73.721  1.00 82.90 ? 239 TYR C O   1 
ATOM   8225  C CB  . TYR C 1 239 ? 87.610  115.878 71.563  1.00 82.90 ? 239 TYR C CB  1 
ATOM   8226  C CG  . TYR C 1 239 ? 87.187  116.812 70.460  1.00 82.90 ? 239 TYR C CG  1 
ATOM   8227  C CD1 . TYR C 1 239 ? 87.383  118.180 70.564  1.00 82.90 ? 239 TYR C CD1 1 
ATOM   8228  C CD2 . TYR C 1 239 ? 86.563  116.327 69.325  1.00 82.90 ? 239 TYR C CD2 1 
ATOM   8229  C CE1 . TYR C 1 239 ? 86.995  119.034 69.562  1.00 82.90 ? 239 TYR C CE1 1 
ATOM   8230  C CE2 . TYR C 1 239 ? 86.163  117.175 68.317  1.00 82.90 ? 239 TYR C CE2 1 
ATOM   8231  C CZ  . TYR C 1 239 ? 86.379  118.527 68.441  1.00 82.90 ? 239 TYR C CZ  1 
ATOM   8232  O OH  . TYR C 1 239 ? 85.984  119.378 67.436  1.00 82.90 ? 239 TYR C OH  1 
ATOM   8233  N N   . PHE C 1 240 ? 90.401  117.944 72.374  1.00 78.35 ? 240 PHE C N   1 
ATOM   8234  C CA  . PHE C 1 240 ? 90.763  119.192 73.048  1.00 78.35 ? 240 PHE C CA  1 
ATOM   8235  C C   . PHE C 1 240 ? 90.726  120.320 72.023  1.00 78.35 ? 240 PHE C C   1 
ATOM   8236  O O   . PHE C 1 240 ? 91.742  120.618 71.390  1.00 78.35 ? 240 PHE C O   1 
ATOM   8237  C CB  . PHE C 1 240 ? 92.144  119.097 73.691  1.00 78.35 ? 240 PHE C CB  1 
ATOM   8238  C CG  . PHE C 1 240 ? 92.190  118.245 74.920  1.00 78.35 ? 240 PHE C CG  1 
ATOM   8239  C CD1 . PHE C 1 240 ? 91.198  118.327 75.874  1.00 78.35 ? 240 PHE C CD1 1 
ATOM   8240  C CD2 . PHE C 1 240 ? 93.242  117.381 75.135  1.00 78.35 ? 240 PHE C CD2 1 
ATOM   8241  C CE1 . PHE C 1 240 ? 91.247  117.553 77.011  1.00 78.35 ? 240 PHE C CE1 1 
ATOM   8242  C CE2 . PHE C 1 240 ? 93.292  116.606 76.272  1.00 78.35 ? 240 PHE C CE2 1 
ATOM   8243  C CZ  . PHE C 1 240 ? 92.293  116.691 77.208  1.00 78.35 ? 240 PHE C CZ  1 
ATOM   8244  N N   . ASP C 1 241 ? 89.574  120.963 71.860  1.00 81.48 ? 241 ASP C N   1 
ATOM   8245  C CA  . ASP C 1 241 ? 89.454  122.002 70.844  1.00 81.48 ? 241 ASP C CA  1 
ATOM   8246  C C   . ASP C 1 241 ? 90.338  123.183 71.219  1.00 81.48 ? 241 ASP C C   1 
ATOM   8247  O O   . ASP C 1 241 ? 90.077  123.875 72.205  1.00 81.48 ? 241 ASP C O   1 
ATOM   8248  C CB  . ASP C 1 241 ? 88.004  122.438 70.680  1.00 81.48 ? 241 ASP C CB  1 
ATOM   8249  C CG  . ASP C 1 241 ? 87.767  123.164 69.369  1.00 81.48 ? 241 ASP C CG  1 
ATOM   8250  O OD1 . ASP C 1 241 ? 87.882  122.520 68.306  1.00 81.48 ? 241 ASP C OD1 1 
ATOM   8251  O OD2 . ASP C 1 241 ? 87.478  124.378 69.397  1.00 81.48 ? 241 ASP C OD2 1 
ATOM   8252  N N   . TYR C 1 242 ? 91.380  123.418 70.424  1.00 77.50 ? 242 TYR C N   1 
ATOM   8253  C CA  . TYR C 1 242 ? 92.374  124.447 70.698  1.00 77.50 ? 242 TYR C CA  1 
ATOM   8254  C C   . TYR C 1 242 ? 92.520  125.455 69.566  1.00 77.50 ? 242 TYR C C   1 
ATOM   8255  O O   . TYR C 1 242 ? 93.441  126.274 69.600  1.00 77.50 ? 242 TYR C O   1 
ATOM   8256  C CB  . TYR C 1 242 ? 93.731  123.800 70.961  1.00 77.50 ? 242 TYR C CB  1 
ATOM   8257  C CG  . TYR C 1 242 ? 94.291  123.155 69.722  1.00 77.50 ? 242 TYR C CG  1 
ATOM   8258  C CD1 . TYR C 1 242 ? 93.850  121.910 69.311  1.00 77.50 ? 242 TYR C CD1 1 
ATOM   8259  C CD2 . TYR C 1 242 ? 95.241  123.799 68.946  1.00 77.50 ? 242 TYR C CD2 1 
ATOM   8260  C CE1 . TYR C 1 242 ? 94.348  121.319 68.175  1.00 77.50 ? 242 TYR C CE1 1 
ATOM   8261  C CE2 . TYR C 1 242 ? 95.746  123.214 67.807  1.00 77.50 ? 242 TYR C CE2 1 
ATOM   8262  C CZ  . TYR C 1 242 ? 95.295  121.972 67.427  1.00 77.50 ? 242 TYR C CZ  1 
ATOM   8263  O OH  . TYR C 1 242 ? 95.791  121.377 66.292  1.00 77.50 ? 242 TYR C OH  1 
ATOM   8264  N N   . THR C 1 243 ? 91.657  125.413 68.555  1.00 78.19 ? 243 THR C N   1 
ATOM   8265  C CA  . THR C 1 243 ? 91.883  126.241 67.377  1.00 78.19 ? 243 THR C CA  1 
ATOM   8266  C C   . THR C 1 243 ? 91.653  127.719 67.673  1.00 78.19 ? 243 THR C C   1 
ATOM   8267  O O   . THR C 1 243 ? 92.503  128.557 67.363  1.00 78.19 ? 243 THR C O   1 
ATOM   8268  C CB  . THR C 1 243 ? 91.005  125.762 66.219  1.00 78.19 ? 243 THR C CB  1 
ATOM   8269  O OG1 . THR C 1 243 ? 91.159  126.648 65.105  1.00 78.19 ? 243 THR C OG1 1 
ATOM   8270  C CG2 . THR C 1 243 ? 89.544  125.662 66.619  1.00 78.19 ? 243 THR C CG2 1 
ATOM   8271  N N   . LYS C 1 244 ? 90.525  128.059 68.294  1.00 75.43 ? 244 LYS C N   1 
ATOM   8272  C CA  . LYS C 1 244 ? 90.155  129.461 68.444  1.00 75.43 ? 244 LYS C CA  1 
ATOM   8273  C C   . LYS C 1 244 ? 91.146  130.206 69.321  1.00 75.43 ? 244 LYS C C   1 
ATOM   8274  O O   . LYS C 1 244 ? 91.445  131.382 69.075  1.00 75.43 ? 244 LYS C O   1 
ATOM   8275  C CB  . LYS C 1 244 ? 88.749  129.560 69.016  1.00 75.43 ? 244 LYS C CB  1 
ATOM   8276  C CG  . LYS C 1 244 ? 87.747  128.771 68.228  1.00 75.43 ? 244 LYS C CG  1 
ATOM   8277  C CD  . LYS C 1 244 ? 86.516  128.492 69.046  1.00 75.43 ? 244 LYS C CD  1 
ATOM   8278  C CE  . LYS C 1 244 ? 86.826  127.520 70.155  1.00 75.43 ? 244 LYS C CE  1 
ATOM   8279  N NZ  . LYS C 1 244 ? 85.593  127.170 70.904  1.00 75.43 ? 244 LYS C NZ  1 
ATOM   8280  N N   . ILE C 1 245 ? 91.661  129.540 70.354  1.00 75.34 ? 245 ILE C N   1 
ATOM   8281  C CA  . ILE C 1 245 ? 92.660  130.173 71.203  1.00 75.34 ? 245 ILE C CA  1 
ATOM   8282  C C   . ILE C 1 245 ? 93.873  130.552 70.379  1.00 75.34 ? 245 ILE C C   1 
ATOM   8283  O O   . ILE C 1 245 ? 94.433  131.640 70.535  1.00 75.34 ? 245 ILE C O   1 
ATOM   8284  C CB  . ILE C 1 245 ? 93.045  129.249 72.369  1.00 75.34 ? 245 ILE C CB  1 
ATOM   8285  C CG1 . ILE C 1 245 ? 91.816  128.833 73.164  1.00 75.34 ? 245 ILE C CG1 1 
ATOM   8286  C CG2 . ILE C 1 245 ? 94.016  129.939 73.291  1.00 75.34 ? 245 ILE C CG2 1 
ATOM   8287  C CD1 . ILE C 1 245 ? 92.141  127.897 74.302  1.00 75.34 ? 245 ILE C CD1 1 
ATOM   8288  N N   . LYS C 1 246 ? 94.303  129.658 69.494  1.00 76.41 ? 246 LYS C N   1 
ATOM   8289  C CA  . LYS C 1 246 ? 95.456  129.945 68.652  1.00 76.41 ? 246 LYS C CA  1 
ATOM   8290  C C   . LYS C 1 246 ? 95.155  131.084 67.686  1.00 76.41 ? 246 LYS C C   1 
ATOM   8291  O O   . LYS C 1 246 ? 95.972  131.998 67.511  1.00 76.41 ? 246 LYS C O   1 
ATOM   8292  C CB  . LYS C 1 246 ? 95.855  128.677 67.904  1.00 76.41 ? 246 LYS C CB  1 
ATOM   8293  C CG  . LYS C 1 246 ? 97.321  128.560 67.575  1.00 76.41 ? 246 LYS C CG  1 
ATOM   8294  C CD  . LYS C 1 246 ? 97.575  127.300 66.780  1.00 76.41 ? 246 LYS C CD  1 
ATOM   8295  C CE  . LYS C 1 246 ? 98.895  127.370 66.044  1.00 76.41 ? 246 LYS C CE  1 
ATOM   8296  N NZ  . LYS C 1 246 ? 99.014  126.275 65.047  1.00 76.41 ? 246 LYS C NZ  1 
ATOM   8297  N N   . GLU C 1 247 ? 93.970  131.053 67.072  1.00 79.04 ? 247 GLU C N   1 
ATOM   8298  C CA  . GLU C 1 247 ? 93.566  132.108 66.151  1.00 79.04 ? 247 GLU C CA  1 
ATOM   8299  C C   . GLU C 1 247 ? 93.601  133.470 66.824  1.00 79.04 ? 247 GLU C C   1 
ATOM   8300  O O   . GLU C 1 247 ? 93.987  134.467 66.206  1.00 79.04 ? 247 GLU C O   1 
ATOM   8301  C CB  . GLU C 1 247 ? 92.164  131.821 65.624  1.00 79.04 ? 247 GLU C CB  1 
ATOM   8302  C CG  . GLU C 1 247 ? 92.013  130.467 64.970  1.00 79.04 ? 247 GLU C CG  1 
ATOM   8303  C CD  . GLU C 1 247 ? 90.569  130.025 64.890  1.00 79.04 ? 247 GLU C CD  1 
ATOM   8304  O OE1 . GLU C 1 247 ? 89.699  130.733 65.436  1.00 79.04 ? 247 GLU C OE1 1 
ATOM   8305  O OE2 . GLU C 1 247 ? 90.299  128.962 64.295  1.00 79.04 ? 247 GLU C OE2 1 
ATOM   8306  N N   . PHE C 1 248 ? 93.196  133.537 68.091  1.00 77.85 ? 248 PHE C N   1 
ATOM   8307  C CA  . PHE C 1 248 ? 93.190  134.836 68.751  1.00 77.85 ? 248 PHE C CA  1 
ATOM   8308  C C   . PHE C 1 248 ? 94.565  135.227 69.274  1.00 77.85 ? 248 PHE C C   1 
ATOM   8309  O O   . PHE C 1 248 ? 95.006  136.360 69.069  1.00 77.85 ? 248 PHE C O   1 
ATOM   8310  C CB  . PHE C 1 248 ? 92.196  134.866 69.902  1.00 77.85 ? 248 PHE C CB  1 
ATOM   8311  C CG  . PHE C 1 248 ? 92.317  136.100 70.746  1.00 77.85 ? 248 PHE C CG  1 
ATOM   8312  C CD1 . PHE C 1 248 ? 91.933  137.327 70.248  1.00 77.85 ? 248 PHE C CD1 1 
ATOM   8313  C CD2 . PHE C 1 248 ? 92.849  136.038 72.018  1.00 77.85 ? 248 PHE C CD2 1 
ATOM   8314  C CE1 . PHE C 1 248 ? 92.038  138.454 71.014  1.00 77.85 ? 248 PHE C CE1 1 
ATOM   8315  C CE2 . PHE C 1 248 ? 92.965  137.169 72.783  1.00 77.85 ? 248 PHE C CE2 1 
ATOM   8316  C CZ  . PHE C 1 248 ? 92.561  138.378 72.281  1.00 77.85 ? 248 PHE C CZ  1 
ATOM   8317  N N   . MET C 1 249 ? 95.246  134.328 69.974  1.00 77.07 ? 249 MET C N   1 
ATOM   8318  C CA  . MET C 1 249 ? 96.537  134.670 70.541  1.00 77.07 ? 249 MET C CA  1 
ATOM   8319  C C   . MET C 1 249 ? 97.613  134.850 69.486  1.00 77.07 ? 249 MET C C   1 
ATOM   8320  O O   . MET C 1 249 ? 98.704  135.318 69.818  1.00 77.07 ? 249 MET C O   1 
ATOM   8321  C CB  . MET C 1 249 ? 96.975  133.599 71.535  1.00 77.07 ? 249 MET C CB  1 
ATOM   8322  C CG  . MET C 1 249 ? 96.214  133.613 72.841  1.00 77.07 ? 249 MET C CG  1 
ATOM   8323  S SD  . MET C 1 249 ? 96.665  132.228 73.899  1.00 77.07 ? 249 MET C SD  1 
ATOM   8324  C CE  . MET C 1 249 ? 98.427  132.480 74.088  1.00 77.07 ? 249 MET C CE  1 
ATOM   8325  N N   . SER C 1 250 ? 97.338  134.491 68.233  1.00 80.84 ? 250 SER C N   1 
ATOM   8326  C CA  . SER C 1 250 ? 98.337  134.648 67.187  1.00 80.84 ? 250 SER C CA  1 
ATOM   8327  C C   . SER C 1 250 ? 98.312  136.028 66.545  1.00 80.84 ? 250 SER C C   1 
ATOM   8328  O O   . SER C 1 250 ? 99.233  136.357 65.791  1.00 80.84 ? 250 SER C O   1 
ATOM   8329  C CB  . SER C 1 250 ? 98.142  133.576 66.117  1.00 80.84 ? 250 SER C CB  1 
ATOM   8330  O OG  . SER C 1 250 ? 98.384  132.289 66.656  1.00 80.84 ? 250 SER C OG  1 
ATOM   8331  N N   . GLU C 1 251 ? 97.303  136.843 66.840  1.00 83.45 ? 251 GLU C N   1 
ATOM   8332  C CA  . GLU C 1 251 ? 97.170  138.149 66.212  1.00 83.45 ? 251 GLU C CA  1 
ATOM   8333  C C   . GLU C 1 251 ? 98.242  139.113 66.721  1.00 83.45 ? 251 GLU C C   1 
ATOM   8334  O O   . GLU C 1 251 ? 99.159  138.748 67.460  1.00 83.45 ? 251 GLU C O   1 
ATOM   8335  C CB  . GLU C 1 251 ? 95.791  138.735 66.483  1.00 83.45 ? 251 GLU C CB  1 
ATOM   8336  C CG  . GLU C 1 251 ? 94.663  137.784 66.211  1.00 83.45 ? 251 GLU C CG  1 
ATOM   8337  C CD  . GLU C 1 251 ? 93.475  138.029 67.110  1.00 83.45 ? 251 GLU C CD  1 
ATOM   8338  O OE1 . GLU C 1 251 ? 93.582  138.867 68.028  1.00 83.45 ? 251 GLU C OE1 1 
ATOM   8339  O OE2 . GLU C 1 251 ? 92.436  137.373 66.907  1.00 83.45 ? 251 GLU C OE2 1 
ATOM   8340  N N   . GLU C 1 252 ? 98.113  140.369 66.300  1.00 87.33 ? 252 GLU C N   1 
ATOM   8341  C CA  . GLU C 1 252 ? 99.048  141.418 66.676  1.00 87.33 ? 252 GLU C CA  1 
ATOM   8342  C C   . GLU C 1 252 ? 98.444  142.472 67.591  1.00 87.33 ? 252 GLU C C   1 
ATOM   8343  O O   . GLU C 1 252 ? 99.139  142.967 68.477  1.00 87.33 ? 252 GLU C O   1 
ATOM   8344  C CB  . GLU C 1 252 ? 99.600  142.095 65.416  1.00 87.33 ? 252 GLU C CB  1 
ATOM   8345  C CG  . GLU C 1 252 ? 98.595  142.963 64.679  1.00 87.33 ? 252 GLU C CG  1 
ATOM   8346  C CD  . GLU C 1 252 ? 97.638  142.168 63.813  1.00 87.33 ? 252 GLU C CD  1 
ATOM   8347  O OE1 . GLU C 1 252 ? 97.536  140.936 63.993  1.00 87.33 ? 252 GLU C OE1 1 
ATOM   8348  O OE2 . GLU C 1 252 ? 96.976  142.781 62.951  1.00 87.33 ? 252 GLU C OE2 1 
ATOM   8349  N N   . LYS C 1 253 ? 97.167  142.816 67.412  1.00 87.66 ? 253 LYS C N   1 
ATOM   8350  C CA  . LYS C 1 253 ? 96.525  143.757 68.323  1.00 87.66 ? 253 LYS C CA  1 
ATOM   8351  C C   . LYS C 1 253 ? 96.420  143.161 69.718  1.00 87.66 ? 253 LYS C C   1 
ATOM   8352  O O   . LYS C 1 253 ? 96.513  143.876 70.722  1.00 87.66 ? 253 LYS C O   1 
ATOM   8353  C CB  . LYS C 1 253 ? 95.147  144.151 67.789  1.00 87.66 ? 253 LYS C CB  1 
ATOM   8354  C CG  . LYS C 1 253 ? 94.606  145.443 68.371  1.00 87.66 ? 253 LYS C CG  1 
ATOM   8355  C CD  . LYS C 1 253 ? 93.161  145.670 67.969  1.00 87.66 ? 253 LYS C CD  1 
ATOM   8356  C CE  . LYS C 1 253 ? 92.239  144.672 68.647  1.00 87.66 ? 253 LYS C CE  1 
ATOM   8357  N NZ  . LYS C 1 253 ? 92.165  144.878 70.118  1.00 87.66 ? 253 LYS C NZ  1 
ATOM   8358  N N   . THR C 1 254 ? 96.219  141.848 69.800  1.00 83.55 ? 254 THR C N   1 
ATOM   8359  C CA  . THR C 1 254 ? 96.364  141.162 71.076  1.00 83.55 ? 254 THR C CA  1 
ATOM   8360  C C   . THR C 1 254 ? 97.792  141.265 71.580  1.00 83.55 ? 254 THR C C   1 
ATOM   8361  O O   . THR C 1 254 ? 98.041  141.718 72.701  1.00 83.55 ? 254 THR C O   1 
ATOM   8362  C CB  . THR C 1 254 ? 95.967  139.699 70.927  1.00 83.55 ? 254 THR C CB  1 
ATOM   8363  O OG1 . THR C 1 254 ? 94.664  139.622 70.343  1.00 83.55 ? 254 THR C OG1 1 
ATOM   8364  C CG2 . THR C 1 254 ? 95.965  139.018 72.273  1.00 83.55 ? 254 THR C CG2 1 
ATOM   8365  N N   . HIS C 1 255 ? 98.750  140.877 70.744  1.00 83.10 ? 255 HIS C N   1 
ATOM   8366  C CA  . HIS C 1 255 ? 100.127 140.745 71.186  1.00 83.10 ? 255 HIS C CA  1 
ATOM   8367  C C   . HIS C 1 255 ? 100.773 142.073 71.546  1.00 83.10 ? 255 HIS C C   1 
ATOM   8368  O O   . HIS C 1 255 ? 101.861 142.069 72.130  1.00 83.10 ? 255 HIS C O   1 
ATOM   8369  C CB  . HIS C 1 255 ? 100.951 140.045 70.110  1.00 83.10 ? 255 HIS C CB  1 
ATOM   8370  C CG  . HIS C 1 255 ? 102.212 139.439 70.631  1.00 83.10 ? 255 HIS C CG  1 
ATOM   8371  N ND1 . HIS C 1 255 ? 103.214 140.192 71.202  1.00 83.10 ? 255 HIS C ND1 1 
ATOM   8372  C CD2 . HIS C 1 255 ? 102.629 138.153 70.683  1.00 83.10 ? 255 HIS C CD2 1 
ATOM   8373  C CE1 . HIS C 1 255 ? 104.200 139.397 71.576  1.00 83.10 ? 255 HIS C CE1 1 
ATOM   8374  N NE2 . HIS C 1 255 ? 103.870 138.155 71.271  1.00 83.10 ? 255 HIS C NE2 1 
ATOM   8375  N N   . GLU C 1 256 ? 100.148 143.200 71.214  1.00 86.32 ? 256 GLU C N   1 
ATOM   8376  C CA  . GLU C 1 256 ? 100.724 144.481 71.606  1.00 86.32 ? 256 GLU C CA  1 
ATOM   8377  C C   . GLU C 1 256 ? 100.399 144.836 73.051  1.00 86.32 ? 256 GLU C C   1 
ATOM   8378  O O   . GLU C 1 256 ? 101.200 145.504 73.713  1.00 86.32 ? 256 GLU C O   1 
ATOM   8379  C CB  . GLU C 1 256 ? 100.240 145.597 70.677  1.00 86.32 ? 256 GLU C CB  1 
ATOM   8380  C CG  . GLU C 1 256 ? 98.776  145.944 70.831  1.00 86.32 ? 256 GLU C CG  1 
ATOM   8381  C CD  . GLU C 1 256 ? 98.309  146.987 69.837  1.00 86.32 ? 256 GLU C CD  1 
ATOM   8382  O OE1 . GLU C 1 256 ? 99.123  147.421 68.997  1.00 86.32 ? 256 GLU C OE1 1 
ATOM   8383  O OE2 . GLU C 1 256 ? 97.125  147.378 69.896  1.00 86.32 ? 256 GLU C OE2 1 
ATOM   8384  N N   . THR C 1 257 ? 99.244  144.402 73.555  1.00 84.01 ? 257 THR C N   1 
ATOM   8385  C CA  . THR C 1 257 ? 98.789  144.755 74.894  1.00 84.01 ? 257 THR C CA  1 
ATOM   8386  C C   . THR C 1 257 ? 99.121  143.691 75.935  1.00 84.01 ? 257 THR C C   1 
ATOM   8387  O O   . THR C 1 257 ? 99.522  144.030 77.049  1.00 84.01 ? 257 THR C O   1 
ATOM   8388  C CB  . THR C 1 257 ? 97.281  145.047 74.875  1.00 84.01 ? 257 THR C CB  1 
ATOM   8389  O OG1 . THR C 1 257 ? 96.838  145.392 76.191  1.00 84.01 ? 257 THR C OG1 1 
ATOM   8390  C CG2 . THR C 1 257 ? 96.488  143.865 74.353  1.00 84.01 ? 257 THR C CG2 1 
ATOM   8391  N N   . MET C 1 258 ? 98.980  142.413 75.597  1.00 81.21 ? 258 MET C N   1 
ATOM   8392  C CA  . MET C 1 258 ? 99.264  141.362 76.561  1.00 81.21 ? 258 MET C CA  1 
ATOM   8393  C C   . MET C 1 258 ? 100.743 141.028 76.580  1.00 81.21 ? 258 MET C C   1 
ATOM   8394  O O   . MET C 1 258 ? 101.454 141.199 75.593  1.00 81.21 ? 258 MET C O   1 
ATOM   8395  C CB  . MET C 1 258 ? 98.463  140.105 76.241  1.00 81.21 ? 258 MET C CB  1 
ATOM   8396  C CG  . MET C 1 258 ? 98.695  139.541 74.860  1.00 81.21 ? 258 MET C CG  1 
ATOM   8397  S SD  . MET C 1 258 ? 100.085 138.417 74.700  1.00 81.21 ? 258 MET C SD  1 
ATOM   8398  C CE  . MET C 1 258 ? 99.379  136.951 75.436  1.00 81.21 ? 258 MET C CE  1 
ATOM   8399  N N   . MET C 1 259 ? 101.208 140.539 77.717  1.00 79.12 ? 259 MET C N   1 
ATOM   8400  C CA  . MET C 1 259 ? 102.565 140.024 77.816  1.00 79.12 ? 259 MET C CA  1 
ATOM   8401  C C   . MET C 1 259 ? 102.462 138.530 77.592  1.00 79.12 ? 259 MET C C   1 
ATOM   8402  O O   . MET C 1 259 ? 101.873 137.815 78.408  1.00 79.12 ? 259 MET C O   1 
ATOM   8403  C CB  . MET C 1 259 ? 103.207 140.330 79.164  1.00 79.12 ? 259 MET C CB  1 
ATOM   8404  C CG  . MET C 1 259 ? 104.671 139.923 79.231  1.00 79.12 ? 259 MET C CG  1 
ATOM   8405  S SD  . MET C 1 259 ? 105.416 140.280 80.829  1.00 79.12 ? 259 MET C SD  1 
ATOM   8406  C CE  . MET C 1 259 ? 105.415 142.068 80.814  1.00 79.12 ? 259 MET C CE  1 
ATOM   8407  N N   . VAL C 1 260 ? 103.012 138.059 76.475  1.00 75.94 ? 260 VAL C N   1 
ATOM   8408  C CA  . VAL C 1 260 ? 102.818 136.665 76.125  1.00 75.94 ? 260 VAL C CA  1 
ATOM   8409  C C   . VAL C 1 260 ? 103.719 135.755 76.943  1.00 75.94 ? 260 VAL C C   1 
ATOM   8410  O O   . VAL C 1 260 ? 103.428 134.563 77.080  1.00 75.94 ? 260 VAL C O   1 
ATOM   8411  C CB  . VAL C 1 260 ? 103.030 136.470 74.615  1.00 75.94 ? 260 VAL C CB  1 
ATOM   8412  C CG1 . VAL C 1 260 ? 104.483 136.634 74.256  1.00 75.94 ? 260 VAL C CG1 1 
ATOM   8413  C CG2 . VAL C 1 260 ? 102.484 135.130 74.161  1.00 75.94 ? 260 VAL C CG2 1 
ATOM   8414  N N   . ASP C 1 261 ? 104.781 136.285 77.530  1.00 75.24 ? 261 ASP C N   1 
ATOM   8415  C CA  . ASP C 1 261 ? 105.720 135.437 78.244  1.00 75.24 ? 261 ASP C CA  1 
ATOM   8416  C C   . ASP C 1 261 ? 105.303 135.126 79.672  1.00 75.24 ? 261 ASP C C   1 
ATOM   8417  O O   . ASP C 1 261 ? 105.963 134.311 80.318  1.00 75.24 ? 261 ASP C O   1 
ATOM   8418  C CB  . ASP C 1 261 ? 107.100 136.077 78.228  1.00 75.24 ? 261 ASP C CB  1 
ATOM   8419  C CG  . ASP C 1 261 ? 107.735 136.023 76.863  1.00 75.24 ? 261 ASP C CG  1 
ATOM   8420  O OD1 . ASP C 1 261 ? 107.002 135.798 75.878  1.00 75.24 ? 261 ASP C OD1 1 
ATOM   8421  O OD2 . ASP C 1 261 ? 108.969 136.184 76.779  1.00 75.24 ? 261 ASP C OD2 1 
ATOM   8422  N N   . ARG C 1 262 ? 104.246 135.737 80.190  1.00 74.19 ? 262 ARG C N   1 
ATOM   8423  C CA  . ARG C 1 262 ? 103.681 135.301 81.463  1.00 74.19 ? 262 ARG C CA  1 
ATOM   8424  C C   . ARG C 1 262 ? 102.505 134.375 81.175  1.00 74.19 ? 262 ARG C C   1 
ATOM   8425  O O   . ARG C 1 262 ? 101.355 134.645 81.509  1.00 74.19 ? 262 ARG C O   1 
ATOM   8426  C CB  . ARG C 1 262 ? 103.264 136.498 82.314  1.00 74.19 ? 262 ARG C CB  1 
ATOM   8427  C CG  . ARG C 1 262 ? 104.379 137.471 82.639  1.00 74.19 ? 262 ARG C CG  1 
ATOM   8428  C CD  . ARG C 1 262 ? 105.320 136.939 83.702  1.00 74.19 ? 262 ARG C CD  1 
ATOM   8429  N NE  . ARG C 1 262 ? 106.420 136.177 83.116  1.00 74.19 ? 262 ARG C NE  1 
ATOM   8430  C CZ  . ARG C 1 262 ? 107.480 135.741 83.791  1.00 74.19 ? 262 ARG C CZ  1 
ATOM   8431  N NH1 . ARG C 1 262 ? 107.595 135.986 85.089  1.00 74.19 ? 262 ARG C NH1 1 
ATOM   8432  N NH2 . ARG C 1 262 ? 108.426 135.055 83.168  1.00 74.19 ? 262 ARG C NH2 1 
ATOM   8433  N N   . SER C 1 263 ? 102.828 133.259 80.531  1.00 66.92 ? 263 SER C N   1 
ATOM   8434  C CA  . SER C 1 263 ? 101.812 132.329 80.072  1.00 66.92 ? 263 SER C CA  1 
ATOM   8435  C C   . SER C 1 263 ? 102.172 130.910 80.478  1.00 66.92 ? 263 SER C C   1 
ATOM   8436  O O   . SER C 1 263 ? 103.348 130.540 80.524  1.00 66.92 ? 263 SER C O   1 
ATOM   8437  C CB  . SER C 1 263 ? 101.641 132.405 78.555  1.00 66.92 ? 263 SER C CB  1 
ATOM   8438  O OG  . SER C 1 263 ? 101.562 133.749 78.129  1.00 66.92 ? 263 SER C OG  1 
ATOM   8439  N N   . TYR C 1 264 ? 101.147 130.117 80.772  1.00 61.64 ? 264 TYR C N   1 
ATOM   8440  C CA  . TYR C 1 264 ? 101.346 128.694 80.971  1.00 61.64 ? 264 TYR C CA  1 
ATOM   8441  C C   . TYR C 1 264 ? 100.105 127.956 80.509  1.00 61.64 ? 264 TYR C C   1 
ATOM   8442  O O   . TYR C 1 264 ? 99.082  128.559 80.192  1.00 61.64 ? 264 TYR C O   1 
ATOM   8443  C CB  . TYR C 1 264 ? 101.676 128.339 82.430  1.00 61.64 ? 264 TYR C CB  1 
ATOM   8444  C CG  . TYR C 1 264 ? 100.621 128.610 83.490  1.00 61.64 ? 264 TYR C CG  1 
ATOM   8445  C CD1 . TYR C 1 264 ? 99.493  127.811 83.599  1.00 61.64 ? 264 TYR C CD1 1 
ATOM   8446  C CD2 . TYR C 1 264 ? 100.759 129.654 84.385  1.00 61.64 ? 264 TYR C CD2 1 
ATOM   8447  C CE1 . TYR C 1 264 ? 98.542  128.043 84.560  1.00 61.64 ? 264 TYR C CE1 1 
ATOM   8448  C CE2 . TYR C 1 264 ? 99.816  129.875 85.362  1.00 61.64 ? 264 TYR C CE2 1 
ATOM   8449  C CZ  . TYR C 1 264 ? 98.705  129.074 85.434  1.00 61.64 ? 264 TYR C CZ  1 
ATOM   8450  O OH  . TYR C 1 264 ? 97.751  129.295 86.396  1.00 61.64 ? 264 TYR C OH  1 
ATOM   8451  N N   . LEU C 1 265 ? 100.205 126.632 80.476  1.00 60.76 ? 265 LEU C N   1 
ATOM   8452  C CA  . LEU C 1 265 ? 99.033  125.785 80.324  1.00 60.76 ? 265 LEU C CA  1 
ATOM   8453  C C   . LEU C 1 265 ? 99.055  124.739 81.421  1.00 60.76 ? 265 LEU C C   1 
ATOM   8454  O O   . LEU C 1 265 ? 100.127 124.335 81.873  1.00 60.76 ? 265 LEU C O   1 
ATOM   8455  C CB  . LEU C 1 265 ? 98.964  125.107 78.958  1.00 60.76 ? 265 LEU C CB  1 
ATOM   8456  C CG  . LEU C 1 265 ? 99.885  123.960 78.556  1.00 60.76 ? 265 LEU C CG  1 
ATOM   8457  C CD1 . LEU C 1 265 ? 99.291  122.617 78.935  1.00 60.76 ? 265 LEU C CD1 1 
ATOM   8458  C CD2 . LEU C 1 265 ? 100.114 123.998 77.072  1.00 60.76 ? 265 LEU C CD2 1 
ATOM   8459  N N   . SER C 1 266 ? 97.881  124.289 81.835  1.00 60.55 ? 266 SER C N   1 
ATOM   8460  C CA  . SER C 1 266 ? 97.770  123.488 83.038  1.00 60.55 ? 266 SER C CA  1 
ATOM   8461  C C   . SER C 1 266 ? 96.864  122.290 82.805  1.00 60.55 ? 266 SER C C   1 
ATOM   8462  O O   . SER C 1 266 ? 96.150  122.204 81.804  1.00 60.55 ? 266 SER C O   1 
ATOM   8463  C CB  . SER C 1 266 ? 97.252  124.336 84.197  1.00 60.55 ? 266 SER C CB  1 
ATOM   8464  O OG  . SER C 1 266 ? 95.966  124.846 83.911  1.00 60.55 ? 266 SER C OG  1 
ATOM   8465  N N   . PHE C 1 267 ? 96.907  121.364 83.757  1.00 53.48 ? 267 PHE C N   1 
ATOM   8466  C CA  . PHE C 1 267 ? 96.192  120.104 83.646  1.00 53.48 ? 267 PHE C CA  1 
ATOM   8467  C C   . PHE C 1 267 ? 96.160  119.446 85.013  1.00 53.48 ? 267 PHE C C   1 
ATOM   8468  O O   . PHE C 1 267 ? 97.003  119.714 85.874  1.00 53.48 ? 267 PHE C O   1 
ATOM   8469  C CB  . PHE C 1 267 ? 96.855  119.169 82.636  1.00 53.48 ? 267 PHE C CB  1 
ATOM   8470  C CG  . PHE C 1 267 ? 98.256  118.794 83.007  1.00 53.48 ? 267 PHE C CG  1 
ATOM   8471  C CD1 . PHE C 1 267 ? 99.315  119.554 82.585  1.00 53.48 ? 267 PHE C CD1 1 
ATOM   8472  C CD2 . PHE C 1 267 ? 98.508  117.696 83.795  1.00 53.48 ? 267 PHE C CD2 1 
ATOM   8473  C CE1 . PHE C 1 267 ? 100.586 119.225 82.932  1.00 53.48 ? 267 PHE C CE1 1 
ATOM   8474  C CE2 . PHE C 1 267 ? 99.785  117.371 84.144  1.00 53.48 ? 267 PHE C CE2 1 
ATOM   8475  C CZ  . PHE C 1 267 ? 100.825 118.136 83.711  1.00 53.48 ? 267 PHE C CZ  1 
ATOM   8476  N N   . ASP C 1 268 ? 95.206  118.546 85.185  1.00 57.39 ? 268 ASP C N   1 
ATOM   8477  C CA  . ASP C 1 268 ? 95.045  117.815 86.428  1.00 57.39 ? 268 ASP C CA  1 
ATOM   8478  C C   . ASP C 1 268 ? 95.703  116.448 86.320  1.00 57.39 ? 268 ASP C C   1 
ATOM   8479  O O   . ASP C 1 268 ? 95.507  115.731 85.335  1.00 57.39 ? 268 ASP C O   1 
ATOM   8480  C CB  . ASP C 1 268 ? 93.568  117.656 86.748  1.00 57.39 ? 268 ASP C CB  1 
ATOM   8481  C CG  . ASP C 1 268 ? 92.873  118.973 86.876  1.00 57.39 ? 268 ASP C CG  1 
ATOM   8482  O OD1 . ASP C 1 268 ? 93.537  119.960 87.232  1.00 57.39 ? 268 ASP C OD1 1 
ATOM   8483  O OD2 . ASP C 1 268 ? 91.664  119.031 86.603  1.00 57.39 ? 268 ASP C OD2 1 
ATOM   8484  N N   . CYS C 1 269 ? 96.473  116.085 87.343  1.00 55.62 ? 269 CYS C N   1 
ATOM   8485  C CA  . CYS C 1 269 ? 97.065  114.752 87.430  1.00 55.62 ? 269 CYS C CA  1 
ATOM   8486  C C   . CYS C 1 269 ? 95.969  113.775 87.826  1.00 55.62 ? 269 CYS C C   1 
ATOM   8487  O O   . CYS C 1 269 ? 95.777  113.452 88.995  1.00 55.62 ? 269 CYS C O   1 
ATOM   8488  C CB  . CYS C 1 269 ? 98.222  114.741 88.416  1.00 55.62 ? 269 CYS C CB  1 
ATOM   8489  S SG  . CYS C 1 269 ? 99.544  115.872 87.976  1.00 55.62 ? 269 CYS C SG  1 
ATOM   8490  N N   . LEU C 1 270 ? 95.233  113.305 86.826  1.00 61.65 ? 270 LEU C N   1 
ATOM   8491  C CA  . LEU C 1 270 ? 94.077  112.453 87.038  1.00 61.65 ? 270 LEU C CA  1 
ATOM   8492  C C   . LEU C 1 270 ? 93.912  111.555 85.823  1.00 61.65 ? 270 LEU C C   1 
ATOM   8493  O O   . LEU C 1 270 ? 94.807  111.446 84.982  1.00 61.65 ? 270 LEU C O   1 
ATOM   8494  C CB  . LEU C 1 270 ? 92.821  113.294 87.280  1.00 61.65 ? 270 LEU C CB  1 
ATOM   8495  C CG  . LEU C 1 270 ? 92.553  113.786 88.697  1.00 61.65 ? 270 LEU C CG  1 
ATOM   8496  C CD1 . LEU C 1 270 ? 91.226  114.509 88.742  1.00 61.65 ? 270 LEU C CD1 1 
ATOM   8497  C CD2 . LEU C 1 270 ? 92.566  112.626 89.666  1.00 61.65 ? 270 LEU C CD2 1 
ATOM   8498  N N   . ASP C 1 271 ? 92.763  110.904 85.740  1.00 68.12 ? 271 ASP C N   1 
ATOM   8499  C CA  . ASP C 1 271 ? 92.389  110.124 84.571  1.00 68.12 ? 271 ASP C CA  1 
ATOM   8500  C C   . ASP C 1 271 ? 92.231  111.069 83.390  1.00 68.12 ? 271 ASP C C   1 
ATOM   8501  O O   . ASP C 1 271 ? 91.281  111.859 83.358  1.00 68.12 ? 271 ASP C O   1 
ATOM   8502  C CB  . ASP C 1 271 ? 91.093  109.357 84.832  1.00 68.12 ? 271 ASP C CB  1 
ATOM   8503  C CG  . ASP C 1 271 ? 90.836  108.278 83.806  1.00 68.12 ? 271 ASP C CG  1 
ATOM   8504  O OD1 . ASP C 1 271 ? 91.557  108.232 82.792  1.00 68.12 ? 271 ASP C OD1 1 
ATOM   8505  O OD2 . ASP C 1 271 ? 89.912  107.468 84.015  1.00 68.12 ? 271 ASP C OD2 1 
ATOM   8506  N N   . PRO C 1 272 ? 93.129  111.020 82.402  1.00 68.08 ? 272 PRO C N   1 
ATOM   8507  C CA  . PRO C 1 272 ? 93.082  112.009 81.315  1.00 68.08 ? 272 PRO C CA  1 
ATOM   8508  C C   . PRO C 1 272 ? 91.761  112.046 80.590  1.00 68.08 ? 272 PRO C C   1 
ATOM   8509  O O   . PRO C 1 272 ? 91.526  112.986 79.826  1.00 68.08 ? 272 PRO C O   1 
ATOM   8510  C CB  . PRO C 1 272 ? 94.220  111.574 80.386  1.00 68.08 ? 272 PRO C CB  1 
ATOM   8511  C CG  . PRO C 1 272 ? 94.513  110.187 80.759  1.00 68.08 ? 272 PRO C CG  1 
ATOM   8512  C CD  . PRO C 1 272 ? 94.217  110.055 82.211  1.00 68.08 ? 272 PRO C CD  1 
ATOM   8513  N N   . ALA C 1 273 ? 90.889  111.065 80.807  1.00 70.37 ? 273 ALA C N   1 
ATOM   8514  C CA  . ALA C 1 273 ? 89.509  111.200 80.369  1.00 70.37 ? 273 ALA C CA  1 
ATOM   8515  C C   . ALA C 1 273 ? 88.711  112.123 81.281  1.00 70.37 ? 273 ALA C C   1 
ATOM   8516  O O   . ALA C 1 273 ? 87.548  112.415 80.987  1.00 70.37 ? 273 ALA C O   1 
ATOM   8517  C CB  . ALA C 1 273 ? 88.847  109.826 80.298  1.00 70.37 ? 273 ALA C CB  1 
ATOM   8518  N N   . LYS C 1 274 ? 89.307  112.591 82.377  1.00 70.20 ? 274 LYS C N   1 
ATOM   8519  C CA  . LYS C 1 274 ? 88.629  113.495 83.292  1.00 70.20 ? 274 LYS C CA  1 
ATOM   8520  C C   . LYS C 1 274 ? 89.326  114.838 83.433  1.00 70.20 ? 274 LYS C C   1 
ATOM   8521  O O   . LYS C 1 274 ? 88.682  115.810 83.844  1.00 70.20 ? 274 LYS C O   1 
ATOM   8522  C CB  . LYS C 1 274 ? 88.510  112.852 84.675  1.00 70.20 ? 274 LYS C CB  1 
ATOM   8523  C CG  . LYS C 1 274 ? 87.930  111.461 84.654  1.00 70.20 ? 274 LYS C CG  1 
ATOM   8524  C CD  . LYS C 1 274 ? 86.501  111.483 84.164  1.00 70.20 ? 274 LYS C CD  1 
ATOM   8525  C CE  . LYS C 1 274 ? 85.962  110.078 83.975  1.00 70.20 ? 274 LYS C CE  1 
ATOM   8526  N NZ  . LYS C 1 274 ? 86.543  109.415 82.777  1.00 70.20 ? 274 LYS C NZ  1 
ATOM   8527  N N   . SER C 1 275 ? 90.612  114.919 83.106  1.00 66.79 ? 275 SER C N   1 
ATOM   8528  C CA  . SER C 1 275 ? 91.354  116.157 83.266  1.00 66.79 ? 275 SER C CA  1 
ATOM   8529  C C   . SER C 1 275 ? 90.905  117.192 82.235  1.00 66.79 ? 275 SER C C   1 
ATOM   8530  O O   . SER C 1 275 ? 90.054  116.942 81.378  1.00 66.79 ? 275 SER C O   1 
ATOM   8531  C CB  . SER C 1 275 ? 92.850  115.900 83.143  1.00 66.79 ? 275 SER C CB  1 
ATOM   8532  O OG  . SER C 1 275 ? 93.310  115.033 84.156  1.00 66.79 ? 275 SER C OG  1 
ATOM   8533  N N   . ARG C 1 276 ? 91.492  118.377 82.335  1.00 65.87 ? 276 ARG C N   1 
ATOM   8534  C CA  . ARG C 1 276 ? 91.233  119.481 81.429  1.00 65.87 ? 276 ARG C CA  1 
ATOM   8535  C C   . ARG C 1 276 ? 92.569  120.068 81.008  1.00 65.87 ? 276 ARG C C   1 
ATOM   8536  O O   . ARG C 1 276 ? 93.617  119.725 81.557  1.00 65.87 ? 276 ARG C O   1 
ATOM   8537  C CB  . ARG C 1 276 ? 90.354  120.547 82.092  1.00 65.87 ? 276 ARG C CB  1 
ATOM   8538  C CG  . ARG C 1 276 ? 88.970  120.052 82.481  1.00 65.87 ? 276 ARG C CG  1 
ATOM   8539  C CD  . ARG C 1 276 ? 88.937  119.525 83.903  1.00 65.87 ? 276 ARG C CD  1 
ATOM   8540  N NE  . ARG C 1 276 ? 89.315  120.526 84.896  1.00 65.87 ? 276 ARG C NE  1 
ATOM   8541  C CZ  . ARG C 1 276 ? 88.460  121.340 85.506  1.00 65.87 ? 276 ARG C CZ  1 
ATOM   8542  N NH1 . ARG C 1 276 ? 87.167  121.283 85.223  1.00 65.87 ? 276 ARG C NH1 1 
ATOM   8543  N NH2 . ARG C 1 276 ? 88.902  122.218 86.395  1.00 65.87 ? 276 ARG C NH2 1 
ATOM   8544  N N   . ILE C 1 277 ? 92.544  120.961 80.025  1.00 66.11 ? 277 ILE C N   1 
ATOM   8545  C CA  . ILE C 1 277 ? 93.751  121.689 79.653  1.00 66.11 ? 277 ILE C CA  1 
ATOM   8546  C C   . ILE C 1 277 ? 93.416  123.170 79.646  1.00 66.11 ? 277 ILE C C   1 
ATOM   8547  O O   . ILE C 1 277 ? 92.617  123.624 78.823  1.00 66.11 ? 277 ILE C O   1 
ATOM   8548  C CB  . ILE C 1 277 ? 94.308  121.249 78.292  1.00 66.11 ? 277 ILE C CB  1 
ATOM   8549  C CG1 . ILE C 1 277 ? 94.771  119.798 78.339  1.00 66.11 ? 277 ILE C CG1 1 
ATOM   8550  C CG2 . ILE C 1 277 ? 95.492  122.114 77.908  1.00 66.11 ? 277 ILE C CG2 1 
ATOM   8551  C CD1 . ILE C 1 277 ? 96.156  119.639 78.870  1.00 66.11 ? 277 ILE C CD1 1 
ATOM   8552  N N   . LYS C 1 278 ? 94.010  123.917 80.569  1.00 65.41 ? 278 LYS C N   1 
ATOM   8553  C CA  . LYS C 1 278 ? 93.785  125.349 80.688  1.00 65.41 ? 278 LYS C CA  1 
ATOM   8554  C C   . LYS C 1 278 ? 95.009  126.087 80.182  1.00 65.41 ? 278 LYS C C   1 
ATOM   8555  O O   . LYS C 1 278 ? 96.121  125.810 80.630  1.00 65.41 ? 278 LYS C O   1 
ATOM   8556  C CB  . LYS C 1 278 ? 93.512  125.747 82.139  1.00 65.41 ? 278 LYS C CB  1 
ATOM   8557  C CG  . LYS C 1 278 ? 92.431  124.943 82.822  1.00 65.41 ? 278 LYS C CG  1 
ATOM   8558  C CD  . LYS C 1 278 ? 92.052  125.533 84.175  1.00 65.41 ? 278 LYS C CD  1 
ATOM   8559  C CE  . LYS C 1 278 ? 93.181  125.424 85.187  1.00 65.41 ? 278 LYS C CE  1 
ATOM   8560  N NZ  . LYS C 1 278 ? 92.802  126.022 86.496  1.00 65.41 ? 278 LYS C NZ  1 
ATOM   8561  N N   . ILE C 1 279 ? 94.803  127.015 79.255  1.00 66.61 ? 279 ILE C N   1 
ATOM   8562  C CA  . ILE C 1 279 ? 95.826  127.972 78.854  1.00 66.61 ? 279 ILE C CA  1 
ATOM   8563  C C   . ILE C 1 279 ? 95.645  129.223 79.699  1.00 66.61 ? 279 ILE C C   1 
ATOM   8564  O O   . ILE C 1 279 ? 94.555  129.499 80.197  1.00 66.61 ? 279 ILE C O   1 
ATOM   8565  C CB  . ILE C 1 279 ? 95.762  128.297 77.349  1.00 66.61 ? 279 ILE C CB  1 
ATOM   8566  C CG1 . ILE C 1 279 ? 95.550  127.030 76.524  1.00 66.61 ? 279 ILE C CG1 1 
ATOM   8567  C CG2 . ILE C 1 279 ? 97.051  128.936 76.902  1.00 66.61 ? 279 ILE C CG2 1 
ATOM   8568  C CD1 . ILE C 1 279 ? 96.775  126.159 76.420  1.00 66.61 ? 279 ILE C CD1 1 
ATOM   8569  N N   . TYR C 1 280 ? 96.717  129.994 79.855  1.00 68.17 ? 280 TYR C N   1 
ATOM   8570  C CA  . TYR C 1 280 ? 96.772  131.054 80.852  1.00 68.17 ? 280 TYR C CA  1 
ATOM   8571  C C   . TYR C 1 280 ? 97.753  132.127 80.411  1.00 68.17 ? 280 TYR C C   1 
ATOM   8572  O O   . TYR C 1 280 ? 98.886  131.797 80.061  1.00 68.17 ? 280 TYR C O   1 
ATOM   8573  C CB  . TYR C 1 280 ? 97.226  130.481 82.185  1.00 68.17 ? 280 TYR C CB  1 
ATOM   8574  C CG  . TYR C 1 280 ? 97.415  131.511 83.251  1.00 68.17 ? 280 TYR C CG  1 
ATOM   8575  C CD1 . TYR C 1 280 ? 96.364  131.904 84.056  1.00 68.17 ? 280 TYR C CD1 1 
ATOM   8576  C CD2 . TYR C 1 280 ? 98.641  132.130 83.422  1.00 68.17 ? 280 TYR C CD2 1 
ATOM   8577  C CE1 . TYR C 1 280 ? 96.541  132.854 85.030  1.00 68.17 ? 280 TYR C CE1 1 
ATOM   8578  C CE2 . TYR C 1 280 ? 98.827  133.075 84.384  1.00 68.17 ? 280 TYR C CE2 1 
ATOM   8579  C CZ  . TYR C 1 280 ? 97.779  133.438 85.182  1.00 68.17 ? 280 TYR C CZ  1 
ATOM   8580  O OH  . TYR C 1 280 ? 97.982  134.394 86.138  1.00 68.17 ? 280 TYR C OH  1 
ATOM   8581  N N   . THR C 1 281 ? 97.348  133.400 80.471  1.00 71.45 ? 281 THR C N   1 
ATOM   8582  C CA  . THR C 1 281 ? 98.245  134.502 80.127  1.00 71.45 ? 281 THR C CA  1 
ATOM   8583  C C   . THR C 1 281 ? 97.800  135.771 80.859  1.00 71.45 ? 281 THR C C   1 
ATOM   8584  O O   . THR C 1 281 ? 96.866  135.746 81.663  1.00 71.45 ? 281 THR C O   1 
ATOM   8585  C CB  . THR C 1 281 ? 98.313  134.691 78.608  1.00 71.45 ? 281 THR C CB  1 
ATOM   8586  O OG1 . THR C 1 281 ? 99.502  135.411 78.266  1.00 71.45 ? 281 THR C OG1 1 
ATOM   8587  C CG2 . THR C 1 281 ? 97.114  135.445 78.112  1.00 71.45 ? 281 THR C CG2 1 
ATOM   8588  N N   . GLU C 1 282 ? 98.496  136.887 80.588  1.00 76.01 ? 282 GLU C N   1 
ATOM   8589  C CA  . GLU C 1 282 ? 98.390  138.116 81.375  1.00 76.01 ? 282 GLU C CA  1 
ATOM   8590  C C   . GLU C 1 282 ? 98.369  139.355 80.489  1.00 76.01 ? 282 GLU C C   1 
ATOM   8591  O O   . GLU C 1 282 ? 99.096  139.430 79.491  1.00 76.01 ? 282 GLU C O   1 
ATOM   8592  C CB  . GLU C 1 282 ? 99.557  138.238 82.365  1.00 76.01 ? 282 GLU C CB  1 
ATOM   8593  C CG  . GLU C 1 282 ? 99.528  137.224 83.493  1.00 76.01 ? 282 GLU C CG  1 
ATOM   8594  C CD  . GLU C 1 282 ? 100.598 137.478 84.532  1.00 76.01 ? 282 GLU C CD  1 
ATOM   8595  O OE1 . GLU C 1 282 ? 101.453 138.355 84.304  1.00 76.01 ? 282 GLU C OE1 1 
ATOM   8596  O OE2 . GLU C 1 282 ? 100.584 136.801 85.579  1.00 76.01 ? 282 GLU C OE2 1 
ATOM   8597  N N   . ALA C 1 283 ? 97.565  140.348 80.884  1.00 78.05 ? 283 ALA C N   1 
ATOM   8598  C CA  . ALA C 1 283 ? 97.370  141.556 80.094  1.00 78.05 ? 283 ALA C CA  1 
ATOM   8599  C C   . ALA C 1 283 ? 97.409  142.798 80.976  1.00 78.05 ? 283 ALA C C   1 
ATOM   8600  O O   . ALA C 1 283 ? 97.010  142.769 82.144  1.00 78.05 ? 283 ALA C O   1 
ATOM   8601  C CB  . ALA C 1 283 ? 96.041  141.523 79.338  1.00 78.05 ? 283 ALA C CB  1 
ATOM   8602  N N   . LYS C 1 284 ? 97.898  143.893 80.393  1.00 78.51 ? 284 LYS C N   1 
ATOM   8603  C CA  . LYS C 1 284 ? 97.903  145.223 81.003  1.00 78.51 ? 284 LYS C CA  1 
ATOM   8604  C C   . LYS C 1 284 ? 96.969  146.079 80.164  1.00 78.51 ? 284 LYS C C   1 
ATOM   8605  O O   . LYS C 1 284 ? 97.388  146.648 79.153  1.00 78.51 ? 284 LYS C O   1 
ATOM   8606  C CB  . LYS C 1 284 ? 99.301  145.822 81.033  1.00 78.51 ? 284 LYS C CB  1 
ATOM   8607  C CG  . LYS C 1 284 ? 100.114 145.475 82.251  1.00 78.51 ? 284 LYS C CG  1 
ATOM   8608  C CD  . LYS C 1 284 ? 101.549 145.910 82.061  1.00 78.51 ? 284 LYS C CD  1 
ATOM   8609  C CE  . LYS C 1 284 ? 102.422 145.411 83.188  1.00 78.51 ? 284 LYS C CE  1 
ATOM   8610  N NZ  . LYS C 1 284 ? 103.833 145.273 82.749  1.00 78.51 ? 284 LYS C NZ  1 
ATOM   8611  N N   . VAL C 1 285 ? 95.716  146.186 80.574  1.00 81.66 ? 285 VAL C N   1 
ATOM   8612  C CA  . VAL C 1 285 ? 94.688  146.754 79.716  1.00 81.66 ? 285 VAL C CA  1 
ATOM   8613  C C   . VAL C 1 285 ? 94.248  148.111 80.240  1.00 81.66 ? 285 VAL C C   1 
ATOM   8614  O O   . VAL C 1 285 ? 94.284  148.389 81.442  1.00 81.66 ? 285 VAL C O   1 
ATOM   8615  C CB  . VAL C 1 285 ? 93.485  145.804 79.578  1.00 81.66 ? 285 VAL C CB  1 
ATOM   8616  C CG1 . VAL C 1 285 ? 93.932  144.502 78.964  1.00 81.66 ? 285 VAL C CG1 1 
ATOM   8617  C CG2 . VAL C 1 285 ? 92.842  145.565 80.923  1.00 81.66 ? 285 VAL C CG2 1 
ATOM   8618  N N   . LYS C 1 286 ? 93.817  148.958 79.311  1.00 81.59 ? 286 LYS C N   1 
ATOM   8619  C CA  . LYS C 1 286 ? 93.411  150.327 79.590  1.00 81.59 ? 286 LYS C CA  1 
ATOM   8620  C C   . LYS C 1 286 ? 91.933  150.463 79.910  1.00 81.59 ? 286 LYS C C   1 
ATOM   8621  O O   . LYS C 1 286 ? 91.577  151.042 80.937  1.00 81.59 ? 286 LYS C O   1 
ATOM   8622  C CB  . LYS C 1 286 ? 93.744  151.220 78.397  1.00 81.59 ? 286 LYS C CB  1 
ATOM   8623  C CG  . LYS C 1 286 ? 93.266  152.638 78.548  1.00 81.59 ? 286 LYS C CG  1 
ATOM   8624  C CD  . LYS C 1 286 ? 94.006  153.353 79.656  1.00 81.59 ? 286 LYS C CD  1 
ATOM   8625  C CE  . LYS C 1 286 ? 93.611  154.816 79.704  1.00 81.59 ? 286 LYS C CE  1 
ATOM   8626  N NZ  . LYS C 1 286 ? 92.178  154.985 80.075  1.00 81.59 ? 286 LYS C NZ  1 
ATOM   8627  N N   . THR C 1 287 ? 91.063  149.954 79.052  1.00 83.27 ? 287 THR C N   1 
ATOM   8628  C CA  . THR C 1 287 ? 89.630  150.002 79.276  1.00 83.27 ? 287 THR C CA  1 
ATOM   8629  C C   . THR C 1 287 ? 89.104  148.590 79.472  1.00 83.27 ? 287 THR C C   1 
ATOM   8630  O O   . THR C 1 287 ? 89.740  147.613 79.070  1.00 83.27 ? 287 THR C O   1 
ATOM   8631  C CB  . THR C 1 287 ? 88.896  150.659 78.102  1.00 83.27 ? 287 THR C CB  1 
ATOM   8632  O OG1 . THR C 1 287 ? 88.670  149.685 77.075  1.00 83.27 ? 287 THR C OG1 1 
ATOM   8633  C CG2 . THR C 1 287 ? 89.722  151.793 77.530  1.00 83.27 ? 287 THR C CG2 1 
ATOM   8634  N N   . LEU C 1 288 ? 87.940  148.485 80.110  1.00 83.66 ? 288 LEU C N   1 
ATOM   8635  C CA  . LEU C 1 288 ? 87.302  147.180 80.214  1.00 83.66 ? 288 LEU C CA  1 
ATOM   8636  C C   . LEU C 1 288 ? 86.842  146.700 78.845  1.00 83.66 ? 288 LEU C C   1 
ATOM   8637  O O   . LEU C 1 288 ? 86.913  145.502 78.540  1.00 83.66 ? 288 LEU C O   1 
ATOM   8638  C CB  . LEU C 1 288 ? 86.139  147.239 81.203  1.00 83.66 ? 288 LEU C CB  1 
ATOM   8639  C CG  . LEU C 1 288 ? 84.889  148.036 80.839  1.00 83.66 ? 288 LEU C CG  1 
ATOM   8640  C CD1 . LEU C 1 288 ? 83.841  147.129 80.232  1.00 83.66 ? 288 LEU C CD1 1 
ATOM   8641  C CD2 . LEU C 1 288 ? 84.342  148.739 82.059  1.00 83.66 ? 288 LEU C CD2 1 
ATOM   8642  N N   . GLU C 1 289 ? 86.380  147.625 78.006  1.00 85.53 ? 289 GLU C N   1 
ATOM   8643  C CA  . GLU C 1 289 ? 86.024  147.276 76.638  1.00 85.53 ? 289 GLU C CA  1 
ATOM   8644  C C   . GLU C 1 289 ? 87.169  146.545 75.952  1.00 85.53 ? 289 GLU C C   1 
ATOM   8645  O O   . GLU C 1 289 ? 86.989  145.450 75.408  1.00 85.53 ? 289 GLU C O   1 
ATOM   8646  C CB  . GLU C 1 289 ? 85.646  148.538 75.865  1.00 85.53 ? 289 GLU C CB  1 
ATOM   8647  C CG  . GLU C 1 289 ? 85.591  148.352 74.360  1.00 85.53 ? 289 GLU C CG  1 
ATOM   8648  C CD  . GLU C 1 289 ? 86.932  148.584 73.693  1.00 85.53 ? 289 GLU C CD  1 
ATOM   8649  O OE1 . GLU C 1 289 ? 87.807  149.211 74.323  1.00 85.53 ? 289 GLU C OE1 1 
ATOM   8650  O OE2 . GLU C 1 289 ? 87.115  148.125 72.549  1.00 85.53 ? 289 GLU C OE2 1 
ATOM   8651  N N   . GLU C 1 290 ? 88.366  147.134 75.981  1.00 84.62 ? 290 GLU C N   1 
ATOM   8652  C CA  . GLU C 1 290 ? 89.496  146.524 75.294  1.00 84.62 ? 290 GLU C CA  1 
ATOM   8653  C C   . GLU C 1 290 ? 89.889  145.217 75.954  1.00 84.62 ? 290 GLU C C   1 
ATOM   8654  O O   . GLU C 1 290 ? 90.532  144.368 75.331  1.00 84.62 ? 290 GLU C O   1 
ATOM   8655  C CB  . GLU C 1 290 ? 90.684  147.479 75.271  1.00 84.62 ? 290 GLU C CB  1 
ATOM   8656  C CG  . GLU C 1 290 ? 91.661  147.270 76.403  1.00 84.62 ? 290 GLU C CG  1 
ATOM   8657  C CD  . GLU C 1 290 ? 92.742  148.322 76.427  1.00 84.62 ? 290 GLU C CD  1 
ATOM   8658  O OE1 . GLU C 1 290 ? 92.555  149.376 75.786  1.00 84.62 ? 290 GLU C OE1 1 
ATOM   8659  O OE2 . GLU C 1 290 ? 93.784  148.092 77.073  1.00 84.62 ? 290 GLU C OE2 1 
ATOM   8660  N N   . ALA C 1 291 ? 89.519  145.036 77.223  1.00 82.92 ? 291 ALA C N   1 
ATOM   8661  C CA  . ALA C 1 291 ? 89.790  143.776 77.899  1.00 82.92 ? 291 ALA C CA  1 
ATOM   8662  C C   . ALA C 1 291 ? 88.819  142.684 77.492  1.00 82.92 ? 291 ALA C C   1 
ATOM   8663  O O   . ALA C 1 291 ? 89.163  141.506 77.597  1.00 82.92 ? 291 ALA C O   1 
ATOM   8664  C CB  . ALA C 1 291 ? 89.750  143.957 79.416  1.00 82.92 ? 291 ALA C CB  1 
ATOM   8665  N N   . TYR C 1 292 ? 87.624  143.047 77.023  1.00 81.06 ? 292 TYR C N   1 
ATOM   8666  C CA  . TYR C 1 292 ? 86.655  142.044 76.595  1.00 81.06 ? 292 TYR C CA  1 
ATOM   8667  C C   . TYR C 1 292 ? 87.236  141.056 75.598  1.00 81.06 ? 292 TYR C C   1 
ATOM   8668  O O   . TYR C 1 292 ? 86.715  139.942 75.462  1.00 81.06 ? 292 TYR C O   1 
ATOM   8669  C CB  . TYR C 1 292 ? 85.438  142.725 75.980  1.00 81.06 ? 292 TYR C CB  1 
ATOM   8670  C CG  . TYR C 1 292 ? 84.315  141.780 75.647  1.00 81.06 ? 292 TYR C CG  1 
ATOM   8671  C CD1 . TYR C 1 292 ? 83.999  140.726 76.487  1.00 81.06 ? 292 TYR C CD1 1 
ATOM   8672  C CD2 . TYR C 1 292 ? 83.563  141.946 74.494  1.00 81.06 ? 292 TYR C CD2 1 
ATOM   8673  C CE1 . TYR C 1 292 ? 82.971  139.862 76.187  1.00 81.06 ? 292 TYR C CE1 1 
ATOM   8674  C CE2 . TYR C 1 292 ? 82.532  141.088 74.186  1.00 81.06 ? 292 TYR C CE2 1 
ATOM   8675  C CZ  . TYR C 1 292 ? 82.239  140.050 75.038  1.00 81.06 ? 292 TYR C CZ  1 
ATOM   8676  O OH  . TYR C 1 292 ? 81.212  139.192 74.737  1.00 81.06 ? 292 TYR C OH  1 
ATOM   8677  N N   . SER C 1 293 ? 88.311  141.428 74.906  1.00 78.64 ? 293 SER C N   1 
ATOM   8678  C CA  . SER C 1 293 ? 88.914  140.525 73.936  1.00 78.64 ? 293 SER C CA  1 
ATOM   8679  C C   . SER C 1 293 ? 89.395  139.243 74.604  1.00 78.64 ? 293 SER C C   1 
ATOM   8680  O O   . SER C 1 293 ? 89.002  138.140 74.209  1.00 78.64 ? 293 SER C O   1 
ATOM   8681  C CB  . SER C 1 293 ? 90.062  141.228 73.215  1.00 78.64 ? 293 SER C CB  1 
ATOM   8682  O OG  . SER C 1 293 ? 91.251  141.174 73.979  1.00 78.64 ? 293 SER C OG  1 
ATOM   8683  N N   . PHE C 1 294 ? 90.238  139.371 75.631  1.00 76.96 ? 294 PHE C N   1 
ATOM   8684  C CA  . PHE C 1 294 ? 90.790  138.194 76.299  1.00 76.96 ? 294 PHE C CA  1 
ATOM   8685  C C   . PHE C 1 294 ? 89.695  137.296 76.843  1.00 76.96 ? 294 PHE C C   1 
ATOM   8686  O O   . PHE C 1 294 ? 89.787  136.069 76.753  1.00 76.96 ? 294 PHE C O   1 
ATOM   8687  C CB  . PHE C 1 294 ? 91.718  138.620 77.426  1.00 76.96 ? 294 PHE C CB  1 
ATOM   8688  C CG  . PHE C 1 294 ? 92.936  139.315 76.954  1.00 76.96 ? 294 PHE C CG  1 
ATOM   8689  C CD1 . PHE C 1 294 ? 92.875  140.625 76.533  1.00 76.96 ? 294 PHE C CD1 1 
ATOM   8690  C CD2 . PHE C 1 294 ? 94.141  138.657 76.918  1.00 76.96 ? 294 PHE C CD2 1 
ATOM   8691  C CE1 . PHE C 1 294 ? 93.990  141.265 76.090  1.00 76.96 ? 294 PHE C CE1 1 
ATOM   8692  C CE2 . PHE C 1 294 ? 95.258  139.292 76.478  1.00 76.96 ? 294 PHE C CE2 1 
ATOM   8693  C CZ  . PHE C 1 294 ? 95.185  140.600 76.062  1.00 76.96 ? 294 PHE C CZ  1 
ATOM   8694  N N   . TRP C 1 295 ? 88.661  137.889 77.425  1.00 75.35 ? 295 TRP C N   1 
ATOM   8695  C CA  . TRP C 1 295 ? 87.506  137.107 77.832  1.00 75.35 ? 295 TRP C CA  1 
ATOM   8696  C C   . TRP C 1 295 ? 86.873  136.392 76.651  1.00 75.35 ? 295 TRP C C   1 
ATOM   8697  O O   . TRP C 1 295 ? 86.342  135.288 76.807  1.00 75.35 ? 295 TRP C O   1 
ATOM   8698  C CB  . TRP C 1 295 ? 86.483  138.013 78.498  1.00 75.35 ? 295 TRP C CB  1 
ATOM   8699  C CG  . TRP C 1 295 ? 85.374  137.282 79.113  1.00 75.35 ? 295 TRP C CG  1 
ATOM   8700  C CD1 . TRP C 1 295 ? 84.131  137.105 78.606  1.00 75.35 ? 295 TRP C CD1 1 
ATOM   8701  C CD2 . TRP C 1 295 ? 85.397  136.623 80.369  1.00 75.35 ? 295 TRP C CD2 1 
ATOM   8702  N NE1 . TRP C 1 295 ? 83.370  136.371 79.469  1.00 75.35 ? 295 TRP C NE1 1 
ATOM   8703  C CE2 . TRP C 1 295 ? 84.129  136.064 80.566  1.00 75.35 ? 295 TRP C CE2 1 
ATOM   8704  C CE3 . TRP C 1 295 ? 86.371  136.453 81.353  1.00 75.35 ? 295 TRP C CE3 1 
ATOM   8705  C CZ2 . TRP C 1 295 ? 83.809  135.342 81.703  1.00 75.35 ? 295 TRP C CZ2 1 
ATOM   8706  C CZ3 . TRP C 1 295 ? 86.055  135.742 82.475  1.00 75.35 ? 295 TRP C CZ3 1 
ATOM   8707  C CH2 . TRP C 1 295 ? 84.786  135.193 82.645  1.00 75.35 ? 295 TRP C CH2 1 
ATOM   8708  N N   . SER C 1 296 ? 86.917  136.998 75.464  1.00 78.24 ? 296 SER C N   1 
ATOM   8709  C CA  . SER C 1 296 ? 86.179  136.495 74.316  1.00 78.24 ? 296 SER C CA  1 
ATOM   8710  C C   . SER C 1 296 ? 87.072  135.968 73.201  1.00 78.24 ? 296 SER C C   1 
ATOM   8711  O O   . SER C 1 296 ? 86.553  135.550 72.163  1.00 78.24 ? 296 SER C O   1 
ATOM   8712  C CB  . SER C 1 296 ? 85.273  137.593 73.766  1.00 78.24 ? 296 SER C CB  1 
ATOM   8713  O OG  . SER C 1 296 ? 86.037  138.738 73.439  1.00 78.24 ? 296 SER C OG  1 
ATOM   8714  N N   . LEU C 1 297 ? 88.391  135.971 73.385  1.00 76.90 ? 297 LEU C N   1 
ATOM   8715  C CA  . LEU C 1 297 ? 89.322  135.563 72.332  1.00 76.90 ? 297 LEU C CA  1 
ATOM   8716  C C   . LEU C 1 297 ? 89.095  136.369 71.059  1.00 76.90 ? 297 LEU C C   1 
ATOM   8717  O O   . LEU C 1 297 ? 89.193  135.851 69.946  1.00 76.90 ? 297 LEU C O   1 
ATOM   8718  C CB  . LEU C 1 297 ? 89.221  134.069 72.039  1.00 76.90 ? 297 LEU C CB  1 
ATOM   8719  C CG  . LEU C 1 297 ? 89.655  133.113 73.136  1.00 76.90 ? 297 LEU C CG  1 
ATOM   8720  C CD1 . LEU C 1 297 ? 89.584  131.717 72.608  1.00 76.90 ? 297 LEU C CD1 1 
ATOM   8721  C CD2 . LEU C 1 297 ? 91.056  133.432 73.565  1.00 76.90 ? 297 LEU C CD2 1 
ATOM   8722  N N   . GLY C 1 298 ? 88.796  137.651 71.217  1.00 78.55 ? 298 GLY C N   1 
ATOM   8723  C CA  . GLY C 1 298 ? 88.562  138.513 70.082  1.00 78.55 ? 298 GLY C CA  1 
ATOM   8724  C C   . GLY C 1 298 ? 87.223  138.336 69.415  1.00 78.55 ? 298 GLY C C   1 
ATOM   8725  O O   . GLY C 1 298 ? 87.100  138.635 68.223  1.00 78.55 ? 298 GLY C O   1 
ATOM   8726  N N   . GLY C 1 299 ? 86.218  137.857 70.135  1.00 79.79 ? 299 GLY C N   1 
ATOM   8727  C CA  . GLY C 1 299 ? 84.910  137.625 69.570  1.00 79.79 ? 299 GLY C CA  1 
ATOM   8728  C C   . GLY C 1 299 ? 84.666  136.203 69.124  1.00 79.79 ? 299 GLY C C   1 
ATOM   8729  O O   . GLY C 1 299 ? 83.504  135.806 68.984  1.00 79.79 ? 299 GLY C O   1 
ATOM   8730  N N   . ARG C 1 300 ? 85.724  135.424 68.904  1.00 79.49 ? 300 ARG C N   1 
ATOM   8731  C CA  . ARG C 1 300 ? 85.538  134.039 68.496  1.00 79.49 ? 300 ARG C CA  1 
ATOM   8732  C C   . ARG C 1 300 ? 84.826  133.240 69.575  1.00 79.49 ? 300 ARG C C   1 
ATOM   8733  O O   . ARG C 1 300 ? 83.826  132.567 69.302  1.00 79.49 ? 300 ARG C O   1 
ATOM   8734  C CB  . ARG C 1 300 ? 86.887  133.408 68.164  1.00 79.49 ? 300 ARG C CB  1 
ATOM   8735  C CG  . ARG C 1 300 ? 87.635  134.142 67.084  1.00 79.49 ? 300 ARG C CG  1 
ATOM   8736  C CD  . ARG C 1 300 ? 89.124  134.032 67.265  1.00 79.49 ? 300 ARG C CD  1 
ATOM   8737  N NE  . ARG C 1 300 ? 89.838  134.532 66.096  1.00 79.49 ? 300 ARG C NE  1 
ATOM   8738  C CZ  . ARG C 1 300 ? 90.177  135.802 65.914  1.00 79.49 ? 300 ARG C CZ  1 
ATOM   8739  N NH1 . ARG C 1 300 ? 89.874  136.708 66.831  1.00 79.49 ? 300 ARG C NH1 1 
ATOM   8740  N NH2 . ARG C 1 300 ? 90.826  136.169 64.820  1.00 79.49 ? 300 ARG C NH2 1 
ATOM   8741  N N   . LEU C 1 301 ? 85.311  133.320 70.809  1.00 80.74 ? 301 LEU C N   1 
ATOM   8742  C CA  . LEU C 1 301 ? 84.772  132.538 71.916  1.00 80.74 ? 301 LEU C CA  1 
ATOM   8743  C C   . LEU C 1 301 ? 83.596  133.320 72.482  1.00 80.74 ? 301 LEU C C   1 
ATOM   8744  O O   . LEU C 1 301 ? 83.777  134.212 73.313  1.00 80.74 ? 301 LEU C O   1 
ATOM   8745  C CB  . LEU C 1 301 ? 85.840  132.300 72.975  1.00 80.74 ? 301 LEU C CB  1 
ATOM   8746  C CG  . LEU C 1 301 ? 85.659  131.080 73.877  1.00 80.74 ? 301 LEU C CG  1 
ATOM   8747  C CD1 . LEU C 1 301 ? 86.937  130.801 74.636  1.00 80.74 ? 301 LEU C CD1 1 
ATOM   8748  C CD2 . LEU C 1 301 ? 84.491  131.209 74.815  1.00 80.74 ? 301 LEU C CD2 1 
ATOM   8749  N N   . SER C 1 302 ? 82.388  132.982 72.046  1.00 84.24 ? 302 SER C N   1 
ATOM   8750  C CA  . SER C 1 302 ? 81.216  133.753 72.421  1.00 84.24 ? 302 SER C CA  1 
ATOM   8751  C C   . SER C 1 302 ? 80.065  132.815 72.745  1.00 84.24 ? 302 SER C C   1 
ATOM   8752  O O   . SER C 1 302 ? 79.923  131.750 72.141  1.00 84.24 ? 302 SER C O   1 
ATOM   8753  C CB  . SER C 1 302 ? 80.816  134.717 71.304  1.00 84.24 ? 302 SER C CB  1 
ATOM   8754  O OG  . SER C 1 302 ? 81.945  135.427 70.835  1.00 84.24 ? 302 SER C OG  1 
ATOM   8755  N N   . GLY C 1 303 ? 79.241  133.227 73.705  1.00 92.18 ? 303 GLY C N   1 
ATOM   8756  C CA  . GLY C 1 303 ? 78.094  132.452 74.111  1.00 92.18 ? 303 GLY C CA  1 
ATOM   8757  C C   . GLY C 1 303 ? 77.165  133.226 75.023  1.00 92.18 ? 303 GLY C C   1 
ATOM   8758  O O   . GLY C 1 303 ? 77.374  134.409 75.301  1.00 92.18 ? 303 GLY C O   1 
ATOM   8759  N N   . PRO C 1 304 ? 76.095  132.574 75.486  1.00 94.82 ? 304 PRO C N   1 
ATOM   8760  C CA  . PRO C 1 304 ? 75.229  133.229 76.480  1.00 94.82 ? 304 PRO C CA  1 
ATOM   8761  C C   . PRO C 1 304 ? 75.930  133.497 77.800  1.00 94.82 ? 304 PRO C C   1 
ATOM   8762  O O   . PRO C 1 304 ? 75.536  134.416 78.528  1.00 94.82 ? 304 PRO C O   1 
ATOM   8763  C CB  . PRO C 1 304 ? 74.068  132.237 76.645  1.00 94.82 ? 304 PRO C CB  1 
ATOM   8764  C CG  . PRO C 1 304 ? 74.095  131.397 75.426  1.00 94.82 ? 304 PRO C CG  1 
ATOM   8765  C CD  . PRO C 1 304 ? 75.524  131.309 74.998  1.00 94.82 ? 304 PRO C CD  1 
ATOM   8766  N N   . GLU C 1 305 ? 76.956  132.718 78.138  1.00 93.86 ? 305 GLU C N   1 
ATOM   8767  C CA  . GLU C 1 305 ? 77.643  132.908 79.410  1.00 93.86 ? 305 GLU C CA  1 
ATOM   8768  C C   . GLU C 1 305 ? 78.887  133.772 79.259  1.00 93.86 ? 305 GLU C C   1 
ATOM   8769  O O   . GLU C 1 305 ? 79.381  134.331 80.248  1.00 93.86 ? 305 GLU C O   1 
ATOM   8770  C CB  . GLU C 1 305 ? 78.002  131.554 80.017  1.00 93.86 ? 305 GLU C CB  1 
ATOM   8771  C CG  . GLU C 1 305 ? 76.807  130.798 80.561  1.00 93.86 ? 305 GLU C CG  1 
ATOM   8772  C CD  . GLU C 1 305 ? 76.126  129.953 79.507  1.00 93.86 ? 305 GLU C CD  1 
ATOM   8773  O OE1 . GLU C 1 305 ? 75.933  130.451 78.380  1.00 93.86 ? 305 GLU C OE1 1 
ATOM   8774  O OE2 . GLU C 1 305 ? 75.778  128.793 79.808  1.00 93.86 ? 305 GLU C OE2 1 
ATOM   8775  N N   . ILE C 1 306 ? 79.406  133.895 78.036  1.00 89.91 ? 306 ILE C N   1 
ATOM   8776  C CA  . ILE C 1 306 ? 80.577  134.731 77.802  1.00 89.91 ? 306 ILE C CA  1 
ATOM   8777  C C   . ILE C 1 306 ? 80.312  136.172 78.206  1.00 89.91 ? 306 ILE C C   1 
ATOM   8778  O O   . ILE C 1 306 ? 81.216  136.864 78.689  1.00 89.91 ? 306 ILE C O   1 
ATOM   8779  C CB  . ILE C 1 306 ? 81.017  134.634 76.332  1.00 89.91 ? 306 ILE C CB  1 
ATOM   8780  C CG1 . ILE C 1 306 ? 81.479  133.216 76.047  1.00 89.91 ? 306 ILE C CG1 1 
ATOM   8781  C CG2 . ILE C 1 306 ? 82.133  135.609 76.046  1.00 89.91 ? 306 ILE C CG2 1 
ATOM   8782  C CD1 . ILE C 1 306 ? 82.429  132.719 77.093  1.00 89.91 ? 306 ILE C CD1 1 
ATOM   8783  N N   . ASP C 1 307 ? 79.076  136.643 78.041  1.00 94.24 ? 307 ASP C N   1 
ATOM   8784  C CA  . ASP C 1 307 ? 78.751  138.007 78.439  1.00 94.24 ? 307 ASP C CA  1 
ATOM   8785  C C   . ASP C 1 307 ? 78.263  138.075 79.881  1.00 94.24 ? 307 ASP C C   1 
ATOM   8786  O O   . ASP C 1 307 ? 78.442  139.101 80.547  1.00 94.24 ? 307 ASP C O   1 
ATOM   8787  C CB  . ASP C 1 307 ? 77.706  138.595 77.493  1.00 94.24 ? 307 ASP C CB  1 
ATOM   8788  C CG  . ASP C 1 307 ? 76.442  137.775 77.447  1.00 94.24 ? 307 ASP C CG  1 
ATOM   8789  O OD1 . ASP C 1 307 ? 75.679  137.809 78.432  1.00 94.24 ? 307 ASP C OD1 1 
ATOM   8790  O OD2 . ASP C 1 307 ? 76.212  137.091 76.429  1.00 94.24 ? 307 ASP C OD2 1 
ATOM   8791  N N   . TYR C 1 308 ? 77.631  137.004 80.374  1.00 92.24 ? 308 TYR C N   1 
ATOM   8792  C CA  . TYR C 1 308 ? 77.265  136.941 81.785  1.00 92.24 ? 308 TYR C CA  1 
ATOM   8793  C C   . TYR C 1 308 ? 78.461  137.245 82.670  1.00 92.24 ? 308 TYR C C   1 
ATOM   8794  O O   . TYR C 1 308 ? 78.410  138.139 83.520  1.00 92.24 ? 308 TYR C O   1 
ATOM   8795  C CB  . TYR C 1 308 ? 76.710  135.563 82.141  1.00 92.24 ? 308 TYR C CB  1 
ATOM   8796  C CG  . TYR C 1 308 ? 75.297  135.319 81.701  1.00 92.24 ? 308 TYR C CG  1 
ATOM   8797  C CD1 . TYR C 1 308 ? 74.617  136.252 80.942  1.00 92.24 ? 308 TYR C CD1 1 
ATOM   8798  C CD2 . TYR C 1 308 ? 74.640  134.152 82.049  1.00 92.24 ? 308 TYR C CD2 1 
ATOM   8799  C CE1 . TYR C 1 308 ? 73.326  136.024 80.534  1.00 92.24 ? 308 TYR C CE1 1 
ATOM   8800  C CE2 . TYR C 1 308 ? 73.350  133.915 81.648  1.00 92.24 ? 308 TYR C CE2 1 
ATOM   8801  C CZ  . TYR C 1 308 ? 72.697  134.854 80.890  1.00 92.24 ? 308 TYR C CZ  1 
ATOM   8802  O OH  . TYR C 1 308 ? 71.404  134.623 80.487  1.00 92.24 ? 308 TYR C OH  1 
ATOM   8803  N N   . GLY C 1 309 ? 79.552  136.504 82.477  1.00 87.70 ? 309 GLY C N   1 
ATOM   8804  C CA  . GLY C 1 309 ? 80.737  136.736 83.284  1.00 87.70 ? 309 GLY C CA  1 
ATOM   8805  C C   . GLY C 1 309 ? 81.354  138.098 83.042  1.00 87.70 ? 309 GLY C C   1 
ATOM   8806  O O   . GLY C 1 309 ? 81.901  138.717 83.963  1.00 87.70 ? 309 GLY C O   1 
ATOM   8807  N N   . PHE C 1 310 ? 81.271  138.591 81.805  1.00 86.31 ? 310 PHE C N   1 
ATOM   8808  C CA  . PHE C 1 310 ? 81.923  139.855 81.495  1.00 86.31 ? 310 PHE C CA  1 
ATOM   8809  C C   . PHE C 1 310 ? 81.223  141.022 82.173  1.00 86.31 ? 310 PHE C C   1 
ATOM   8810  O O   . PHE C 1 310 ? 81.878  141.973 82.613  1.00 86.31 ? 310 PHE C O   1 
ATOM   8811  C CB  . PHE C 1 310 ? 81.976  140.082 79.992  1.00 86.31 ? 310 PHE C CB  1 
ATOM   8812  C CG  . PHE C 1 310 ? 82.533  141.415 79.626  1.00 86.31 ? 310 PHE C CG  1 
ATOM   8813  C CD1 . PHE C 1 310 ? 83.861  141.709 79.879  1.00 86.31 ? 310 PHE C CD1 1 
ATOM   8814  C CD2 . PHE C 1 310 ? 81.731  142.387 79.061  1.00 86.31 ? 310 PHE C CD2 1 
ATOM   8815  C CE1 . PHE C 1 310 ? 84.383  142.939 79.557  1.00 86.31 ? 310 PHE C CE1 1 
ATOM   8816  C CE2 . PHE C 1 310 ? 82.250  143.624 78.737  1.00 86.31 ? 310 PHE C CE2 1 
ATOM   8817  C CZ  . PHE C 1 310 ? 83.577  143.899 78.985  1.00 86.31 ? 310 PHE C CZ  1 
ATOM   8818  N N   . LYS C 1 311 ? 79.893  140.982 82.244  1.00 87.30 ? 311 LYS C N   1 
ATOM   8819  C CA  . LYS C 1 311 ? 79.177  142.029 82.962  1.00 87.30 ? 311 LYS C CA  1 
ATOM   8820  C C   . LYS C 1 311 ? 79.687  142.141 84.385  1.00 87.30 ? 311 LYS C C   1 
ATOM   8821  O O   . LYS C 1 311 ? 79.957  143.240 84.882  1.00 87.30 ? 311 LYS C O   1 
ATOM   8822  C CB  . LYS C 1 311 ? 77.680  141.743 82.966  1.00 87.30 ? 311 LYS C CB  1 
ATOM   8823  C CG  . LYS C 1 311 ? 76.847  142.845 83.609  1.00 87.30 ? 311 LYS C CG  1 
ATOM   8824  C CD  . LYS C 1 311 ? 76.657  142.645 85.108  1.00 87.30 ? 311 LYS C CD  1 
ATOM   8825  C CE  . LYS C 1 311 ? 75.985  141.326 85.420  1.00 87.30 ? 311 LYS C CE  1 
ATOM   8826  N NZ  . LYS C 1 311 ? 75.710  141.211 86.877  1.00 87.30 ? 311 LYS C NZ  1 
ATOM   8827  N N   . ILE C 1 312 ? 79.825  141.002 85.060  1.00 85.49 ? 312 ILE C N   1 
ATOM   8828  C CA  . ILE C 1 312 ? 80.214  141.018 86.463  1.00 85.49 ? 312 ILE C CA  1 
ATOM   8829  C C   . ILE C 1 312 ? 81.651  141.490 86.610  1.00 85.49 ? 312 ILE C C   1 
ATOM   8830  O O   . ILE C 1 312 ? 81.988  142.213 87.560  1.00 85.49 ? 312 ILE C O   1 
ATOM   8831  C CB  . ILE C 1 312 ? 80.004  139.631 87.090  1.00 85.49 ? 312 ILE C CB  1 
ATOM   8832  C CG1 . ILE C 1 312 ? 78.535  139.235 87.006  1.00 85.49 ? 312 ILE C CG1 1 
ATOM   8833  C CG2 . ILE C 1 312 ? 80.431  139.644 88.532  1.00 85.49 ? 312 ILE C CG2 1 
ATOM   8834  C CD1 . ILE C 1 312 ? 78.265  137.806 87.391  1.00 85.49 ? 312 ILE C CD1 1 
ATOM   8835  N N   . VAL C 1 313 ? 82.525  141.098 85.680  1.00 83.55 ? 313 VAL C N   1 
ATOM   8836  C CA  . VAL C 1 313 ? 83.902  141.540 85.850  1.00 83.55 ? 313 VAL C CA  1 
ATOM   8837  C C   . VAL C 1 313 ? 84.027  143.028 85.576  1.00 83.55 ? 313 VAL C C   1 
ATOM   8838  O O   . VAL C 1 313 ? 84.803  143.711 86.242  1.00 83.55 ? 313 VAL C O   1 
ATOM   8839  C CB  . VAL C 1 313 ? 84.896  140.733 84.999  1.00 83.55 ? 313 VAL C CB  1 
ATOM   8840  C CG1 . VAL C 1 313 ? 84.727  141.025 83.529  1.00 83.55 ? 313 VAL C CG1 1 
ATOM   8841  C CG2 . VAL C 1 313 ? 86.316  141.040 85.461  1.00 83.55 ? 313 VAL C CG2 1 
ATOM   8842  N N   . SER C 1 314 ? 83.259  143.575 84.636  1.00 85.72 ? 314 SER C N   1 
ATOM   8843  C CA  . SER C 1 314 ? 83.293  145.023 84.460  1.00 85.72 ? 314 SER C CA  1 
ATOM   8844  C C   . SER C 1 314 ? 82.731  145.723 85.687  1.00 85.72 ? 314 SER C C   1 
ATOM   8845  O O   . SER C 1 314 ? 83.233  146.778 86.102  1.00 85.72 ? 314 SER C O   1 
ATOM   8846  C CB  . SER C 1 314 ? 82.513  145.418 83.211  1.00 85.72 ? 314 SER C CB  1 
ATOM   8847  O OG  . SER C 1 314 ? 81.142  145.605 83.505  1.00 85.72 ? 314 SER C OG  1 
ATOM   8848  N N   . GLN C 1 315 ? 81.695  145.135 86.284  1.00 84.41 ? 315 GLN C N   1 
ATOM   8849  C CA  . GLN C 1 315 ? 81.121  145.662 87.513  1.00 84.41 ? 315 GLN C CA  1 
ATOM   8850  C C   . GLN C 1 315 ? 82.185  145.807 88.593  1.00 84.41 ? 315 GLN C C   1 
ATOM   8851  O O   . GLN C 1 315 ? 82.475  146.916 89.059  1.00 84.41 ? 315 GLN C O   1 
ATOM   8852  C CB  . GLN C 1 315 ? 79.995  144.735 87.967  1.00 84.41 ? 315 GLN C CB  1 
ATOM   8853  C CG  . GLN C 1 315 ? 79.388  145.046 89.313  1.00 84.41 ? 315 GLN C CG  1 
ATOM   8854  C CD  . GLN C 1 315 ? 78.226  144.123 89.624  1.00 84.41 ? 315 GLN C CD  1 
ATOM   8855  O OE1 . GLN C 1 315 ? 77.823  143.317 88.786  1.00 84.41 ? 315 GLN C OE1 1 
ATOM   8856  N NE2 . GLN C 1 315 ? 77.683  144.234 90.830  1.00 84.41 ? 315 GLN C NE2 1 
ATOM   8857  N N   . MET C 1 316 ? 82.801  144.695 88.986  1.00 83.50 ? 316 MET C N   1 
ATOM   8858  C CA  . MET C 1 316 ? 83.793  144.789 90.052  1.00 83.50 ? 316 MET C CA  1 
ATOM   8859  C C   . MET C 1 316 ? 85.029  145.552 89.603  1.00 83.50 ? 316 MET C C   1 
ATOM   8860  O O   . MET C 1 316 ? 85.730  146.137 90.433  1.00 83.50 ? 316 MET C O   1 
ATOM   8861  C CB  . MET C 1 316 ? 84.191  143.412 90.560  1.00 83.50 ? 316 MET C CB  1 
ATOM   8862  C CG  . MET C 1 316 ? 84.731  143.466 91.975  1.00 83.50 ? 316 MET C CG  1 
ATOM   8863  S SD  . MET C 1 316 ? 85.901  142.165 92.360  1.00 83.50 ? 316 MET C SD  1 
ATOM   8864  C CE  . MET C 1 316 ? 87.143  142.447 91.105  1.00 83.50 ? 316 MET C CE  1 
ATOM   8865  N N   . TRP C 1 317 ? 85.299  145.576 88.301  1.00 84.57 ? 317 TRP C N   1 
ATOM   8866  C CA  . TRP C 1 317 ? 86.403  146.354 87.761  1.00 84.57 ? 317 TRP C CA  1 
ATOM   8867  C C   . TRP C 1 317 ? 86.248  147.820 88.118  1.00 84.57 ? 317 TRP C C   1 
ATOM   8868  O O   . TRP C 1 317 ? 87.094  148.400 88.807  1.00 84.57 ? 317 TRP C O   1 
ATOM   8869  C CB  . TRP C 1 317 ? 86.448  146.150 86.244  1.00 84.57 ? 317 TRP C CB  1 
ATOM   8870  C CG  . TRP C 1 317 ? 87.205  147.164 85.441  1.00 84.57 ? 317 TRP C CG  1 
ATOM   8871  C CD1 . TRP C 1 317 ? 86.848  148.458 85.199  1.00 84.57 ? 317 TRP C CD1 1 
ATOM   8872  C CD2 . TRP C 1 317 ? 88.402  146.938 84.701  1.00 84.57 ? 317 TRP C CD2 1 
ATOM   8873  N NE1 . TRP C 1 317 ? 87.772  149.061 84.393  1.00 84.57 ? 317 TRP C NE1 1 
ATOM   8874  C CE2 . TRP C 1 317 ? 88.735  148.146 84.068  1.00 84.57 ? 317 TRP C CE2 1 
ATOM   8875  C CE3 . TRP C 1 317 ? 89.236  145.835 84.526  1.00 84.57 ? 317 TRP C CE3 1 
ATOM   8876  C CZ2 . TRP C 1 317 ? 89.858  148.281 83.272  1.00 84.57 ? 317 TRP C CZ2 1 
ATOM   8877  C CZ3 . TRP C 1 317 ? 90.356  145.975 83.737  1.00 84.57 ? 317 TRP C CZ3 1 
ATOM   8878  C CH2 . TRP C 1 317 ? 90.656  147.187 83.119  1.00 84.57 ? 317 TRP C CH2 1 
ATOM   8879  N N   . ASP C 1 318 ? 85.173  148.444 87.641  1.00 87.45 ? 318 ASP C N   1 
ATOM   8880  C CA  . ASP C 1 318 ? 85.016  149.858 87.941  1.00 87.45 ? 318 ASP C CA  1 
ATOM   8881  C C   . ASP C 1 318 ? 84.767  150.084 89.422  1.00 87.45 ? 318 ASP C C   1 
ATOM   8882  O O   . ASP C 1 318 ? 85.109  151.152 89.938  1.00 87.45 ? 318 ASP C O   1 
ATOM   8883  C CB  . ASP C 1 318 ? 83.919  150.483 87.072  1.00 87.45 ? 318 ASP C CB  1 
ATOM   8884  C CG  . ASP C 1 318 ? 82.516  150.057 87.460  1.00 87.45 ? 318 ASP C CG  1 
ATOM   8885  O OD1 . ASP C 1 318 ? 82.304  149.452 88.529  1.00 87.45 ? 318 ASP C OD1 1 
ATOM   8886  O OD2 . ASP C 1 318 ? 81.595  150.357 86.674  1.00 87.45 ? 318 ASP C OD2 1 
ATOM   8887  N N   . ALA C 1 319 ? 84.221  149.086 90.121  1.00 85.03 ? 319 ALA C N   1 
ATOM   8888  C CA  . ALA C 1 319 ? 84.099  149.182 91.570  1.00 85.03 ? 319 ALA C CA  1 
ATOM   8889  C C   . ALA C 1 319 ? 85.458  149.406 92.224  1.00 85.03 ? 319 ALA C C   1 
ATOM   8890  O O   . ALA C 1 319 ? 85.704  150.453 92.831  1.00 85.03 ? 319 ALA C O   1 
ATOM   8891  C CB  . ALA C 1 319 ? 83.434  147.919 92.118  1.00 85.03 ? 319 ALA C CB  1 
ATOM   8892  N N   . ILE C 1 320 ? 86.366  148.436 92.094  1.00 81.36 ? 320 ILE C N   1 
ATOM   8893  C CA  . ILE C 1 320 ? 87.637  148.519 92.811  1.00 81.36 ? 320 ILE C CA  1 
ATOM   8894  C C   . ILE C 1 320 ? 88.632  149.458 92.157  1.00 81.36 ? 320 ILE C C   1 
ATOM   8895  O O   . ILE C 1 320 ? 89.658  149.772 92.767  1.00 81.36 ? 320 ILE C O   1 
ATOM   8896  C CB  . ILE C 1 320 ? 88.324  147.151 92.959  1.00 81.36 ? 320 ILE C CB  1 
ATOM   8897  C CG1 . ILE C 1 320 ? 89.216  147.144 94.200  1.00 81.36 ? 320 ILE C CG1 1 
ATOM   8898  C CG2 . ILE C 1 320 ? 89.167  146.850 91.738  1.00 81.36 ? 320 ILE C CG2 1 
ATOM   8899  C CD1 . ILE C 1 320 ? 89.661  145.770 94.636  1.00 81.36 ? 320 ILE C CD1 1 
ATOM   8900  N N   . TYR C 1 321 ? 88.373  149.916 90.937  1.00 83.69 ? 321 TYR C N   1 
ATOM   8901  C CA  . TYR C 1 321 ? 89.257  150.887 90.314  1.00 83.69 ? 321 TYR C CA  1 
ATOM   8902  C C   . TYR C 1 321 ? 88.751  152.312 90.446  1.00 83.69 ? 321 TYR C C   1 
ATOM   8903  O O   . TYR C 1 321 ? 89.502  153.249 90.154  1.00 83.69 ? 321 TYR C O   1 
ATOM   8904  C CB  . TYR C 1 321 ? 89.459  150.541 88.840  1.00 83.69 ? 321 TYR C CB  1 
ATOM   8905  C CG  . TYR C 1 321 ? 90.333  149.338 88.658  1.00 83.69 ? 321 TYR C CG  1 
ATOM   8906  C CD1 . TYR C 1 321 ? 91.476  149.185 89.411  1.00 83.69 ? 321 TYR C CD1 1 
ATOM   8907  C CD2 . TYR C 1 321 ? 90.017  148.354 87.739  1.00 83.69 ? 321 TYR C CD2 1 
ATOM   8908  C CE1 . TYR C 1 321 ? 92.284  148.094 89.258  1.00 83.69 ? 321 TYR C CE1 1 
ATOM   8909  C CE2 . TYR C 1 321 ? 90.820  147.253 87.574  1.00 83.69 ? 321 TYR C CE2 1 
ATOM   8910  C CZ  . TYR C 1 321 ? 91.956  147.130 88.340  1.00 83.69 ? 321 TYR C CZ  1 
ATOM   8911  O OH  . TYR C 1 321 ? 92.779  146.040 88.199  1.00 83.69 ? 321 TYR C OH  1 
ATOM   8912  N N   . SER C 1 322 ? 87.505  152.494 90.883  1.00 86.33 ? 322 SER C N   1 
ATOM   8913  C CA  . SER C 1 322 ? 87.020  153.832 91.182  1.00 86.33 ? 322 SER C CA  1 
ATOM   8914  C C   . SER C 1 322 ? 87.813  154.464 92.318  1.00 86.33 ? 322 SER C C   1 
ATOM   8915  O O   . SER C 1 322 ? 87.978  155.687 92.363  1.00 86.33 ? 322 SER C O   1 
ATOM   8916  C CB  . SER C 1 322 ? 85.540  153.765 91.532  1.00 86.33 ? 322 SER C CB  1 
ATOM   8917  O OG  . SER C 1 322 ? 85.343  152.890 92.630  1.00 86.33 ? 322 SER C OG  1 
ATOM   8918  N N   . LYS C 1 323 ? 88.310  153.655 93.246  1.00 85.97 ? 323 LYS C N   1 
ATOM   8919  C CA  . LYS C 1 323 ? 89.089  154.188 94.352  1.00 85.97 ? 323 LYS C CA  1 
ATOM   8920  C C   . LYS C 1 323 ? 90.479  154.596 93.884  1.00 85.97 ? 323 LYS C C   1 
ATOM   8921  O O   . LYS C 1 323 ? 90.914  154.283 92.774  1.00 85.97 ? 323 LYS C O   1 
ATOM   8922  C CB  . LYS C 1 323 ? 89.211  153.164 95.477  1.00 85.97 ? 323 LYS C CB  1 
ATOM   8923  C CG  . LYS C 1 323 ? 87.964  152.351 95.696  1.00 85.97 ? 323 LYS C CG  1 
ATOM   8924  C CD  . LYS C 1 323 ? 86.779  153.231 96.024  1.00 85.97 ? 323 LYS C CD  1 
ATOM   8925  C CE  . LYS C 1 323 ? 85.487  152.441 95.948  1.00 85.97 ? 323 LYS C CE  1 
ATOM   8926  N NZ  . LYS C 1 323 ? 85.346  151.756 94.639  1.00 85.97 ? 323 LYS C NZ  1 
ATOM   8927  N N   . GLU C 1 324 ? 91.175  155.311 94.756  1.00 89.26 ? 324 GLU C N   1 
ATOM   8928  C CA  . GLU C 1 324 ? 92.527  155.758 94.480  1.00 89.26 ? 324 GLU C CA  1 
ATOM   8929  C C   . GLU C 1 324 ? 93.541  154.787 95.068  1.00 89.26 ? 324 GLU C C   1 
ATOM   8930  O O   . GLU C 1 324 ? 93.221  153.931 95.895  1.00 89.26 ? 324 GLU C O   1 
ATOM   8931  C CB  . GLU C 1 324 ? 92.763  157.151 95.056  1.00 89.26 ? 324 GLU C CB  1 
ATOM   8932  C CG  . GLU C 1 324 ? 92.955  157.157 96.556  1.00 89.26 ? 324 GLU C CG  1 
ATOM   8933  C CD  . GLU C 1 324 ? 91.660  156.916 97.298  1.00 89.26 ? 324 GLU C CD  1 
ATOM   8934  O OE1 . GLU C 1 324 ? 90.589  157.074 96.678  1.00 89.26 ? 324 GLU C OE1 1 
ATOM   8935  O OE2 . GLU C 1 324 ? 91.707  156.564 98.494  1.00 89.26 ? 324 GLU C OE2 1 
ATOM   8936  N N   . LEU C 1 325 ? 94.763  154.933 94.635  1.00 87.59 ? 325 LEU C N   1 
ATOM   8937  C CA  . LEU C 1 325 ? 95.830  154.144 95.209  1.00 87.59 ? 325 LEU C CA  1 
ATOM   8938  C C   . LEU C 1 325 ? 96.269  154.761 96.533  1.00 87.59 ? 325 LEU C C   1 
ATOM   8939  O O   . LEU C 1 325 ? 96.141  155.970 96.732  1.00 87.59 ? 325 LEU C O   1 
ATOM   8940  C CB  . LEU C 1 325 ? 97.005  154.075 94.244  1.00 87.59 ? 325 LEU C CB  1 
ATOM   8941  C CG  . LEU C 1 325 ? 98.062  152.993 94.437  1.00 87.59 ? 325 LEU C CG  1 
ATOM   8942  C CD1 . LEU C 1 325 ? 98.532  152.480 93.093  1.00 87.59 ? 325 LEU C CD1 1 
ATOM   8943  C CD2 . LEU C 1 325 ? 99.227  153.533 95.235  1.00 87.59 ? 325 LEU C CD2 1 
ATOM   8944  N N   . PRO C 1 326 ? 96.750  153.949 97.470  1.00 87.60 ? 326 PRO C N   1 
ATOM   8945  C CA  . PRO C 1 326 ? 97.294  154.510 98.711  1.00 87.60 ? 326 PRO C CA  1 
ATOM   8946  C C   . PRO C 1 326 ? 98.452  155.456 98.460  1.00 87.60 ? 326 PRO C C   1 
ATOM   8947  O O   . PRO C 1 326 ? 99.514  155.037 97.993  1.00 87.60 ? 326 PRO C O   1 
ATOM   8948  C CB  . PRO C 1 326 ? 97.748  153.270 99.488  1.00 87.60 ? 326 PRO C CB  1 
ATOM   8949  C CG  . PRO C 1 326 ? 96.877  152.190 98.995  1.00 87.60 ? 326 PRO C CG  1 
ATOM   8950  C CD  . PRO C 1 326 ? 96.582  152.489 97.555  1.00 87.60 ? 326 PRO C CD  1 
ATOM   8951  N N   . GLY C 1 327 ? 98.259  156.729 98.777  1.00 92.31 ? 327 GLY C N   1 
ATOM   8952  C CA  . GLY C 1 327 ? 99.289  157.723 98.591  1.00 92.31 ? 327 GLY C CA  1 
ATOM   8953  C C   . GLY C 1 327 ? 99.175  158.546 97.331  1.00 92.31 ? 327 GLY C C   1 
ATOM   8954  O O   . GLY C 1 327 ? 100.157 159.186 96.942  1.00 92.31 ? 327 GLY C O   1 
ATOM   8955  N N   . GLY C 1 328 ? 98.022  158.536 96.671  1.00 96.00 ? 328 GLY C N   1 
ATOM   8956  C CA  . GLY C 1 328 ? 97.799  159.385 95.523  1.00 96.00 ? 328 GLY C CA  1 
ATOM   8957  C C   . GLY C 1 328 ? 98.556  159.018 94.268  1.00 96.00 ? 328 GLY C C   1 
ATOM   8958  O O   . GLY C 1 328 ? 98.488  159.771 93.291  1.00 96.00 ? 328 GLY C O   1 
ATOM   8959  N N   . LYS C 1 329 ? 99.283  157.903 94.252  1.00 95.92 ? 329 LYS C N   1 
ATOM   8960  C CA  . LYS C 1 329 ? 99.939  157.482 93.023  1.00 95.92 ? 329 LYS C CA  1 
ATOM   8961  C C   . LYS C 1 329 ? 98.894  157.151 91.968  1.00 95.92 ? 329 LYS C C   1 
ATOM   8962  O O   . LYS C 1 329 ? 97.826  156.615 92.275  1.00 95.92 ? 329 LYS C O   1 
ATOM   8963  C CB  . LYS C 1 329 ? 100.841 156.277 93.278  1.00 95.92 ? 329 LYS C CB  1 
ATOM   8964  C CG  . LYS C 1 329 ? 102.109 156.615 94.040  1.00 95.92 ? 329 LYS C CG  1 
ATOM   8965  C CD  . LYS C 1 329 ? 103.135 155.501 93.926  1.00 95.92 ? 329 LYS C CD  1 
ATOM   8966  C CE  . LYS C 1 329 ? 103.419 155.159 92.472  1.00 95.92 ? 329 LYS C CE  1 
ATOM   8967  N NZ  . LYS C 1 329 ? 103.862 156.351 91.698  1.00 95.92 ? 329 LYS C NZ  1 
ATOM   8968  N N   . GLN C 1 330 ? 99.197  157.485 90.721  1.00 95.48 ? 330 GLN C N   1 
ATOM   8969  C CA  . GLN C 1 330 ? 98.201  157.399 89.667  1.00 95.48 ? 330 GLN C CA  1 
ATOM   8970  C C   . GLN C 1 330 ? 98.170  156.011 89.042  1.00 95.48 ? 330 GLN C C   1 
ATOM   8971  O O   . GLN C 1 330 ? 99.198  155.345 88.897  1.00 95.48 ? 330 GLN C O   1 
ATOM   8972  C CB  . GLN C 1 330 ? 98.475  158.448 88.593  1.00 95.48 ? 330 GLN C CB  1 
ATOM   8973  C CG  . GLN C 1 330 ? 98.179  159.853 89.053  1.00 95.48 ? 330 GLN C CG  1 
ATOM   8974  C CD  . GLN C 1 330 ? 96.884  159.932 89.830  1.00 95.48 ? 330 GLN C CD  1 
ATOM   8975  O OE1 . GLN C 1 330 ? 96.880  160.235 91.022  1.00 95.48 ? 330 GLN C OE1 1 
ATOM   8976  N NE2 . GLN C 1 330 ? 95.773  159.653 89.158  1.00 95.48 ? 330 GLN C NE2 1 
ATOM   8977  N N   . ARG C 1 331 ? 96.966  155.577 88.671  1.00 93.00 ? 331 ARG C N   1 
ATOM   8978  C CA  . ARG C 1 331 ? 96.775  154.309 87.974  1.00 93.00 ? 331 ARG C CA  1 
ATOM   8979  C C   . ARG C 1 331 ? 96.709  154.591 86.475  1.00 93.00 ? 331 ARG C C   1 
ATOM   8980  O O   . ARG C 1 331 ? 95.851  155.345 86.008  1.00 93.00 ? 331 ARG C O   1 
ATOM   8981  C CB  . ARG C 1 331 ? 95.531  153.580 88.487  1.00 93.00 ? 331 ARG C CB  1 
ATOM   8982  C CG  . ARG C 1 331 ? 94.196  154.240 88.182  1.00 93.00 ? 331 ARG C CG  1 
ATOM   8983  C CD  . ARG C 1 331 ? 93.022  153.447 88.738  1.00 93.00 ? 331 ARG C CD  1 
ATOM   8984  N NE  . ARG C 1 331 ? 92.979  153.480 90.195  1.00 93.00 ? 331 ARG C NE  1 
ATOM   8985  C CZ  . ARG C 1 331 ? 93.248  152.441 90.975  1.00 93.00 ? 331 ARG C CZ  1 
ATOM   8986  N NH1 . ARG C 1 331 ? 93.579  151.278 90.442  1.00 93.00 ? 331 ARG C NH1 1 
ATOM   8987  N NH2 . ARG C 1 331 ? 93.188  152.570 92.291  1.00 93.00 ? 331 ARG C NH2 1 
ATOM   8988  N N   . GLU C 1 332 ? 97.654  154.025 85.728  1.00 93.00 ? 332 GLU C N   1 
ATOM   8989  C CA  . GLU C 1 332 ? 97.689  154.229 84.286  1.00 93.00 ? 332 GLU C CA  1 
ATOM   8990  C C   . GLU C 1 332 ? 96.923  153.131 83.558  1.00 93.00 ? 332 GLU C C   1 
ATOM   8991  O O   . GLU C 1 332 ? 96.096  153.407 82.684  1.00 93.00 ? 332 GLU C O   1 
ATOM   8992  C CB  . GLU C 1 332 ? 99.142  154.298 83.806  1.00 93.00 ? 332 GLU C CB  1 
ATOM   8993  C CG  . GLU C 1 332 ? 100.028 153.146 84.265  1.00 93.00 ? 332 GLU C CG  1 
ATOM   8994  C CD  . GLU C 1 332 ? 100.567 153.336 85.668  1.00 93.00 ? 332 GLU C CD  1 
ATOM   8995  O OE1 . GLU C 1 332 ? 99.961  154.100 86.445  1.00 93.00 ? 332 GLU C OE1 1 
ATOM   8996  O OE2 . GLU C 1 332 ? 101.602 152.721 85.994  1.00 93.00 ? 332 GLU C OE2 1 
ATOM   8997  N N   . ASN C 1 333 ? 97.183  151.880 83.913  1.00 87.30 ? 333 ASN C N   1 
ATOM   8998  C CA  . ASN C 1 333 ? 96.526  150.735 83.312  1.00 87.30 ? 333 ASN C CA  1 
ATOM   8999  C C   . ASN C 1 333 ? 96.140  149.756 84.412  1.00 87.30 ? 333 ASN C C   1 
ATOM   9000  O O   . ASN C 1 333 ? 96.352  150.004 85.601  1.00 87.30 ? 333 ASN C O   1 
ATOM   9001  C CB  . ASN C 1 333 ? 97.421  150.063 82.262  1.00 87.30 ? 333 ASN C CB  1 
ATOM   9002  C CG  . ASN C 1 333 ? 98.808  149.763 82.784  1.00 87.30 ? 333 ASN C CG  1 
ATOM   9003  O OD1 . ASN C 1 333 ? 99.071  149.864 83.980  1.00 87.30 ? 333 ASN C OD1 1 
ATOM   9004  N ND2 . ASN C 1 333 ? 99.709  149.405 81.883  1.00 87.30 ? 333 ASN C ND2 1 
ATOM   9005  N N   . ASN C 1 334 ? 95.567  148.635 84.007  1.00 81.58 ? 334 ASN C N   1 
ATOM   9006  C CA  . ASN C 1 334 ? 95.025  147.662 84.935  1.00 81.58 ? 334 ASN C CA  1 
ATOM   9007  C C   . ASN C 1 334 ? 95.600  146.291 84.629  1.00 81.58 ? 334 ASN C C   1 
ATOM   9008  O O   . ASN C 1 334 ? 95.576  145.848 83.477  1.00 81.58 ? 334 ASN C O   1 
ATOM   9009  C CB  . ASN C 1 334 ? 93.508  147.654 84.843  1.00 81.58 ? 334 ASN C CB  1 
ATOM   9010  C CG  . ASN C 1 334 ? 92.913  148.944 85.325  1.00 81.58 ? 334 ASN C CG  1 
ATOM   9011  O OD1 . ASN C 1 334 ? 93.088  149.323 86.477  1.00 81.58 ? 334 ASN C OD1 1 
ATOM   9012  N ND2 . ASN C 1 334 ? 92.262  149.664 84.430  1.00 81.58 ? 334 ASN C ND2 1 
ATOM   9013  N N   . HIS C 1 335 ? 96.111  145.628 85.661  1.00 76.51 ? 335 HIS C N   1 
ATOM   9014  C CA  . HIS C 1 335 ? 96.763  144.333 85.517  1.00 76.51 ? 335 HIS C CA  1 
ATOM   9015  C C   . HIS C 1 335 ? 95.723  143.234 85.703  1.00 76.51 ? 335 HIS C C   1 
ATOM   9016  O O   . HIS C 1 335 ? 95.178  143.051 86.803  1.00 76.51 ? 335 HIS C O   1 
ATOM   9017  C CB  . HIS C 1 335 ? 97.908  144.203 86.515  1.00 76.51 ? 335 HIS C CB  1 
ATOM   9018  C CG  . HIS C 1 335 ? 98.899  143.141 86.168  1.00 76.51 ? 335 HIS C CG  1 
ATOM   9019  N ND1 . HIS C 1 335 ? 99.554  143.103 84.959  1.00 76.51 ? 335 HIS C ND1 1 
ATOM   9020  C CD2 . HIS C 1 335 ? 99.378  142.101 86.887  1.00 76.51 ? 335 HIS C CD2 1 
ATOM   9021  C CE1 . HIS C 1 335 ? 100.375 142.070 84.938  1.00 76.51 ? 335 HIS C CE1 1 
ATOM   9022  N NE2 . HIS C 1 335 ? 100.290 141.447 86.098  1.00 76.51 ? 335 HIS C NE2 1 
ATOM   9023  N N   . ILE C 1 336 ? 95.432  142.520 84.619  1.00 72.56 ? 336 ILE C N   1 
ATOM   9024  C CA  . ILE C 1 336 ? 94.463  141.441 84.624  1.00 72.56 ? 336 ILE C CA  1 
ATOM   9025  C C   . ILE C 1 336 ? 95.160  140.176 84.158  1.00 72.56 ? 336 ILE C C   1 
ATOM   9026  O O   . ILE C 1 336 ? 96.176  140.213 83.458  1.00 72.56 ? 336 ILE C O   1 
ATOM   9027  C CB  . ILE C 1 336 ? 93.254  141.756 83.730  1.00 72.56 ? 336 ILE C CB  1 
ATOM   9028  C CG1 . ILE C 1 336 ? 93.582  141.459 82.275  1.00 72.56 ? 336 ILE C CG1 1 
ATOM   9029  C CG2 . ILE C 1 336 ? 92.876  143.205 83.859  1.00 72.56 ? 336 ILE C CG2 1 
ATOM   9030  C CD1 . ILE C 1 336 ? 92.462  141.789 81.344  1.00 72.56 ? 336 ILE C CD1 1 
ATOM   9031  N N   . GLN C 1 337 ? 94.608  139.047 84.570  1.00 70.46 ? 337 GLN C N   1 
ATOM   9032  C CA  . GLN C 1 337 ? 95.088  137.749 84.129  1.00 70.46 ? 337 GLN C CA  1 
ATOM   9033  C C   . GLN C 1 337 ? 93.920  136.997 83.524  1.00 70.46 ? 337 GLN C C   1 
ATOM   9034  O O   . GLN C 1 337 ? 92.765  137.335 83.762  1.00 70.46 ? 337 GLN C O   1 
ATOM   9035  C CB  . GLN C 1 337 ? 95.698  136.950 85.271  1.00 70.46 ? 337 GLN C CB  1 
ATOM   9036  C CG  . GLN C 1 337 ? 96.839  137.650 85.958  1.00 70.46 ? 337 GLN C CG  1 
ATOM   9037  C CD  . GLN C 1 337 ? 97.215  136.976 87.252  1.00 70.46 ? 337 GLN C CD  1 
ATOM   9038  O OE1 . GLN C 1 337 ? 96.384  136.333 87.886  1.00 70.46 ? 337 GLN C OE1 1 
ATOM   9039  N NE2 . GLN C 1 337 ? 98.475  137.105 87.646  1.00 70.46 ? 337 GLN C NE2 1 
ATOM   9040  N N   . ILE C 1 338 ? 94.213  135.971 82.741  1.00 69.12 ? 338 ILE C N   1 
ATOM   9041  C CA  . ILE C 1 338 ? 93.167  135.276 82.012  1.00 69.12 ? 338 ILE C CA  1 
ATOM   9042  C C   . ILE C 1 338 ? 93.560  133.821 81.828  1.00 69.12 ? 338 ILE C C   1 
ATOM   9043  O O   . ILE C 1 338 ? 94.742  133.486 81.699  1.00 69.12 ? 338 ILE C O   1 
ATOM   9044  C CB  . ILE C 1 338 ? 92.889  135.963 80.664  1.00 69.12 ? 338 ILE C CB  1 
ATOM   9045  C CG1 . ILE C 1 338 ? 91.628  135.401 80.026  1.00 69.12 ? 338 ILE C CG1 1 
ATOM   9046  C CG2 . ILE C 1 338 ? 94.072  135.824 79.763  1.00 69.12 ? 338 ILE C CG2 1 
ATOM   9047  C CD1 . ILE C 1 338 ? 90.406  135.601 80.850  1.00 69.12 ? 338 ILE C CD1 1 
ATOM   9048  N N   . ASN C 1 339 ? 92.549  132.958 81.825  1.00 69.48 ? 339 ASN C N   1 
ATOM   9049  C CA  . ASN C 1 339 ? 92.731  131.517 81.812  1.00 69.48 ? 339 ASN C CA  1 
ATOM   9050  C C   . ASN C 1 339 ? 91.566  130.891 81.068  1.00 69.48 ? 339 ASN C C   1 
ATOM   9051  O O   . ASN C 1 339 ? 90.430  130.969 81.527  1.00 69.48 ? 339 ASN C O   1 
ATOM   9052  C CB  . ASN C 1 339 ? 92.796  130.998 83.242  1.00 69.48 ? 339 ASN C CB  1 
ATOM   9053  C CG  . ASN C 1 339 ? 93.093  129.535 83.318  1.00 69.48 ? 339 ASN C CG  1 
ATOM   9054  O OD1 . ASN C 1 339 ? 92.216  128.699 83.106  1.00 69.48 ? 339 ASN C OD1 1 
ATOM   9055  N ND2 . ASN C 1 339 ? 94.338  129.207 83.637  1.00 69.48 ? 339 ASN C ND2 1 
ATOM   9056  N N   . TRP C 1 340 ? 91.842  130.282 79.924  1.00 69.31 ? 340 TRP C N   1 
ATOM   9057  C CA  . TRP C 1 340 ? 90.837  129.563 79.155  1.00 69.31 ? 340 TRP C CA  1 
ATOM   9058  C C   . TRP C 1 340 ? 91.011  128.073 79.387  1.00 69.31 ? 340 TRP C C   1 
ATOM   9059  O O   . TRP C 1 340 ? 92.101  127.610 79.715  1.00 69.31 ? 340 TRP C O   1 
ATOM   9060  C CB  . TRP C 1 340 ? 90.951  129.858 77.662  1.00 69.31 ? 340 TRP C CB  1 
ATOM   9061  C CG  . TRP C 1 340 ? 91.100  131.297 77.345  1.00 69.31 ? 340 TRP C CG  1 
ATOM   9062  C CD1 . TRP C 1 340 ? 90.105  132.197 77.151  1.00 69.31 ? 340 TRP C CD1 1 
ATOM   9063  C CD2 . TRP C 1 340 ? 92.324  132.011 77.184  1.00 69.31 ? 340 TRP C CD2 1 
ATOM   9064  N NE1 . TRP C 1 340 ? 90.630  133.429 76.877  1.00 69.31 ? 340 TRP C NE1 1 
ATOM   9065  C CE2 . TRP C 1 340 ? 91.995  133.339 76.891  1.00 69.31 ? 340 TRP C CE2 1 
ATOM   9066  C CE3 . TRP C 1 340 ? 93.667  131.653 77.260  1.00 69.31 ? 340 TRP C CE3 1 
ATOM   9067  C CZ2 . TRP C 1 340 ? 92.956  134.309 76.673  1.00 69.31 ? 340 TRP C CZ2 1 
ATOM   9068  C CZ3 . TRP C 1 340 ? 94.616  132.614 77.045  1.00 69.31 ? 340 TRP C CZ3 1 
ATOM   9069  C CH2 . TRP C 1 340 ? 94.260  133.926 76.755  1.00 69.31 ? 340 TRP C CH2 1 
ATOM   9070  N N   . GLU C 1 341 ? 89.934  127.322 79.208  1.00 73.58 ? 341 GLU C N   1 
ATOM   9071  C CA  . GLU C 1 341 ? 89.943  125.907 79.540  1.00 73.58 ? 341 GLU C CA  1 
ATOM   9072  C C   . GLU C 1 341 ? 89.271  125.096 78.447  1.00 73.58 ? 341 GLU C C   1 
ATOM   9073  O O   . GLU C 1 341 ? 88.197  125.471 77.968  1.00 73.58 ? 341 GLU C O   1 
ATOM   9074  C CB  . GLU C 1 341 ? 89.225  125.652 80.859  1.00 73.58 ? 341 GLU C CB  1 
ATOM   9075  C CG  . GLU C 1 341 ? 89.378  124.240 81.365  1.00 73.58 ? 341 GLU C CG  1 
ATOM   9076  C CD  . GLU C 1 341 ? 88.638  124.019 82.656  1.00 73.58 ? 341 GLU C CD  1 
ATOM   9077  O OE1 . GLU C 1 341 ? 87.838  124.894 83.039  1.00 73.58 ? 341 GLU C OE1 1 
ATOM   9078  O OE2 . GLU C 1 341 ? 88.897  122.996 83.303  1.00 73.58 ? 341 GLU C OE2 1 
ATOM   9079  N N   . MET C 1 342 ? 89.883  123.962 78.104  1.00 75.00 ? 342 MET C N   1 
ATOM   9080  C CA  . MET C 1 342 ? 89.407  123.048 77.077  1.00 75.00 ? 342 MET C CA  1 
ATOM   9081  C C   . MET C 1 342 ? 89.164  121.678 77.692  1.00 75.00 ? 342 MET C C   1 
ATOM   9082  O O   . MET C 1 342 ? 90.055  121.118 78.349  1.00 75.00 ? 342 MET C O   1 
ATOM   9083  C CB  . MET C 1 342 ? 90.419  122.936 75.940  1.00 75.00 ? 342 MET C CB  1 
ATOM   9084  C CG  . MET C 1 342 ? 90.999  124.258 75.519  1.00 75.00 ? 342 MET C CG  1 
ATOM   9085  S SD  . MET C 1 342 ? 92.351  124.064 74.362  1.00 75.00 ? 342 MET C SD  1 
ATOM   9086  C CE  . MET C 1 342 ? 93.373  122.921 75.260  1.00 75.00 ? 342 MET C CE  1 
ATOM   9087  N N   . SER C 1 343 ? 87.964  121.146 77.471  1.00 79.68 ? 343 SER C N   1 
ATOM   9088  C CA  . SER C 1 343 ? 87.531  119.868 78.010  1.00 79.68 ? 343 SER C CA  1 
ATOM   9089  C C   . SER C 1 343 ? 87.768  118.758 76.996  1.00 79.68 ? 343 SER C C   1 
ATOM   9090  O O   . SER C 1 343 ? 87.992  119.010 75.812  1.00 79.68 ? 343 SER C O   1 
ATOM   9091  C CB  . SER C 1 343 ? 86.056  119.918 78.395  1.00 79.68 ? 343 SER C CB  1 
ATOM   9092  O OG  . SER C 1 343 ? 85.610  118.660 78.864  1.00 79.68 ? 343 SER C OG  1 
ATOM   9093  N N   . ALA C 1 344 ? 87.704  117.514 77.477  1.00 80.92 ? 344 ALA C N   1 
ATOM   9094  C CA  . ALA C 1 344 ? 88.024  116.355 76.651  1.00 80.92 ? 344 ALA C CA  1 
ATOM   9095  C C   . ALA C 1 344 ? 86.803  115.787 75.944  1.00 80.92 ? 344 ALA C C   1 
ATOM   9096  O O   . ALA C 1 344 ? 86.867  115.470 74.751  1.00 80.92 ? 344 ALA C O   1 
ATOM   9097  C CB  . ALA C 1 344 ? 88.675  115.269 77.508  1.00 80.92 ? 344 ALA C CB  1 
ATOM   9098  N N   . LYS C 1 345 ? 85.688  115.660 76.653  1.00 86.61 ? 345 LYS C N   1 
ATOM   9099  C CA  . LYS C 1 345 ? 84.521  115.002 76.086  1.00 86.61 ? 345 LYS C CA  1 
ATOM   9100  C C   . LYS C 1 345 ? 83.814  115.865 75.052  1.00 86.61 ? 345 LYS C C   1 
ATOM   9101  O O   . LYS C 1 345 ? 83.189  115.330 74.129  1.00 86.61 ? 345 LYS C O   1 
ATOM   9102  C CB  . LYS C 1 345 ? 83.549  114.623 77.203  1.00 86.61 ? 345 LYS C CB  1 
ATOM   9103  C CG  . LYS C 1 345 ? 83.476  115.654 78.310  1.00 86.61 ? 345 LYS C CG  1 
ATOM   9104  C CD  . LYS C 1 345 ? 82.527  115.223 79.411  1.00 86.61 ? 345 LYS C CD  1 
ATOM   9105  C CE  . LYS C 1 345 ? 81.078  115.367 78.984  1.00 86.61 ? 345 LYS C CE  1 
ATOM   9106  N NZ  . LYS C 1 345 ? 80.719  116.786 78.714  1.00 86.61 ? 345 LYS C NZ  1 
ATOM   9107  N N   . ASP C 1 346 ? 83.893  117.186 75.179  1.00 89.37 ? 346 ASP C N   1 
ATOM   9108  C CA  . ASP C 1 346 ? 83.142  118.089 74.319  1.00 89.37 ? 346 ASP C CA  1 
ATOM   9109  C C   . ASP C 1 346 ? 84.082  118.991 73.534  1.00 89.37 ? 346 ASP C C   1 
ATOM   9110  O O   . ASP C 1 346 ? 85.307  118.880 73.621  1.00 89.37 ? 346 ASP C O   1 
ATOM   9111  C CB  . ASP C 1 346 ? 82.171  118.944 75.135  1.00 89.37 ? 346 ASP C CB  1 
ATOM   9112  C CG  . ASP C 1 346 ? 81.093  118.124 75.796  1.00 89.37 ? 346 ASP C CG  1 
ATOM   9113  O OD1 . ASP C 1 346 ? 80.968  116.929 75.461  1.00 89.37 ? 346 ASP C OD1 1 
ATOM   9114  O OD2 . ASP C 1 346 ? 80.363  118.673 76.645  1.00 89.37 ? 346 ASP C OD2 1 
ATOM   9115  N N   . SER C 1 347 ? 83.486  119.894 72.760  1.00 88.34 ? 347 SER C N   1 
ATOM   9116  C CA  . SER C 1 347 ? 84.220  120.925 72.032  1.00 88.34 ? 347 SER C CA  1 
ATOM   9117  C C   . SER C 1 347 ? 83.816  122.289 72.589  1.00 88.34 ? 347 SER C C   1 
ATOM   9118  O O   . SER C 1 347 ? 82.947  122.985 72.064  1.00 88.34 ? 347 SER C O   1 
ATOM   9119  C CB  . SER C 1 347 ? 83.943  120.822 70.536  1.00 88.34 ? 347 SER C CB  1 
ATOM   9120  O OG  . SER C 1 347 ? 84.066  119.482 70.098  1.00 88.34 ? 347 SER C OG  1 
ATOM   9121  N N   . SER C 1 348 ? 84.483  122.669 73.672  1.00 84.80 ? 348 SER C N   1 
ATOM   9122  C CA  . SER C 1 348 ? 84.181  123.899 74.383  1.00 84.80 ? 348 SER C CA  1 
ATOM   9123  C C   . SER C 1 348 ? 85.462  124.432 74.995  1.00 84.80 ? 348 SER C C   1 
ATOM   9124  O O   . SER C 1 348 ? 86.393  123.671 75.266  1.00 84.80 ? 348 SER C O   1 
ATOM   9125  C CB  . SER C 1 348 ? 83.126  123.672 75.475  1.00 84.80 ? 348 SER C CB  1 
ATOM   9126  O OG  . SER C 1 348 ? 82.927  124.838 76.253  1.00 84.80 ? 348 SER C OG  1 
ATOM   9127  N N   . VAL C 1 349 ? 85.511  125.743 75.192  1.00 76.88 ? 349 VAL C N   1 
ATOM   9128  C CA  . VAL C 1 349 ? 86.605  126.389 75.901  1.00 76.88 ? 349 VAL C CA  1 
ATOM   9129  C C   . VAL C 1 349 ? 86.053  127.620 76.594  1.00 76.88 ? 349 VAL C C   1 
ATOM   9130  O O   . VAL C 1 349 ? 85.350  128.426 75.977  1.00 76.88 ? 349 VAL C O   1 
ATOM   9131  C CB  . VAL C 1 349 ? 87.769  126.750 74.961  1.00 76.88 ? 349 VAL C CB  1 
ATOM   9132  C CG1 . VAL C 1 349 ? 87.253  127.431 73.717  1.00 76.88 ? 349 VAL C CG1 1 
ATOM   9133  C CG2 . VAL C 1 349 ? 88.761  127.636 75.683  1.00 76.88 ? 349 VAL C CG2 1 
ATOM   9134  N N   . ALA C 1 350 ? 86.352  127.752 77.880  1.00 75.11 ? 350 ALA C N   1 
ATOM   9135  C CA  . ALA C 1 350 ? 85.718  128.750 78.727  1.00 75.11 ? 350 ALA C CA  1 
ATOM   9136  C C   . ALA C 1 350 ? 86.758  129.647 79.388  1.00 75.11 ? 350 ALA C C   1 
ATOM   9137  O O   . ALA C 1 350 ? 87.840  129.182 79.752  1.00 75.11 ? 350 ALA C O   1 
ATOM   9138  C CB  . ALA C 1 350 ? 84.848  128.087 79.806  1.00 75.11 ? 350 ALA C CB  1 
ATOM   9139  N N   . PRO C 1 351 ? 86.454  130.937 79.554  1.00 70.46 ? 351 PRO C N   1 
ATOM   9140  C CA  . PRO C 1 351 ? 87.433  131.853 80.143  1.00 70.46 ? 351 PRO C CA  1 
ATOM   9141  C C   . PRO C 1 351 ? 87.273  132.040 81.644  1.00 70.46 ? 351 PRO C C   1 
ATOM   9142  O O   . PRO C 1 351 ? 86.264  131.651 82.238  1.00 70.46 ? 351 PRO C O   1 
ATOM   9143  C CB  . PRO C 1 351 ? 87.153  133.154 79.393  1.00 70.46 ? 351 PRO C CB  1 
ATOM   9144  C CG  . PRO C 1 351 ? 85.687  133.112 79.189  1.00 70.46 ? 351 PRO C CG  1 
ATOM   9145  C CD  . PRO C 1 351 ? 85.268  131.662 79.084  1.00 70.46 ? 351 PRO C CD  1 
ATOM   9146  N N   . LYS C 1 352 ? 88.292  132.635 82.258  1.00 68.55 ? 352 LYS C N   1 
ATOM   9147  C CA  . LYS C 1 352 ? 88.298  132.958 83.681  1.00 68.55 ? 352 LYS C CA  1 
ATOM   9148  C C   . LYS C 1 352 ? 89.299  134.081 83.894  1.00 68.55 ? 352 LYS C C   1 
ATOM   9149  O O   . LYS C 1 352 ? 90.498  133.901 83.654  1.00 68.55 ? 352 LYS C O   1 
ATOM   9150  C CB  . LYS C 1 352 ? 88.655  131.737 84.517  1.00 68.55 ? 352 LYS C CB  1 
ATOM   9151  C CG  . LYS C 1 352 ? 88.942  132.030 85.961  1.00 68.55 ? 352 LYS C CG  1 
ATOM   9152  C CD  . LYS C 1 352 ? 89.409  130.773 86.631  1.00 68.55 ? 352 LYS C CD  1 
ATOM   9153  C CE  . LYS C 1 352 ? 90.158  131.068 87.894  1.00 68.55 ? 352 LYS C CE  1 
ATOM   9154  N NZ  . LYS C 1 352 ? 90.958  129.896 88.331  1.00 68.55 ? 352 LYS C NZ  1 
ATOM   9155  N N   . LEU C 1 353 ? 88.805  135.226 84.340  1.00 70.11 ? 353 LEU C N   1 
ATOM   9156  C CA  . LEU C 1 353 ? 89.553  136.469 84.400  1.00 70.11 ? 353 LEU C CA  1 
ATOM   9157  C C   . LEU C 1 353 ? 89.980  136.762 85.833  1.00 70.11 ? 353 LEU C C   1 
ATOM   9158  O O   . LEU C 1 353 ? 89.410  136.240 86.788  1.00 70.11 ? 353 LEU C O   1 
ATOM   9159  C CB  . LEU C 1 353 ? 88.689  137.600 83.834  1.00 70.11 ? 353 LEU C CB  1 
ATOM   9160  C CG  . LEU C 1 353 ? 89.031  139.085 83.803  1.00 70.11 ? 353 LEU C CG  1 
ATOM   9161  C CD1 . LEU C 1 353 ? 90.431  139.351 83.329  1.00 70.11 ? 353 LEU C CD1 1 
ATOM   9162  C CD2 . LEU C 1 353 ? 88.069  139.709 82.843  1.00 70.11 ? 353 LEU C CD2 1 
ATOM   9163  N N   . TYR C 1 354 ? 91.014  137.577 85.971  1.00 68.75 ? 354 TYR C N   1 
ATOM   9164  C CA  . TYR C 1 354 ? 91.579  137.946 87.257  1.00 68.75 ? 354 TYR C CA  1 
ATOM   9165  C C   . TYR C 1 354 ? 91.824  139.441 87.256  1.00 68.75 ? 354 TYR C C   1 
ATOM   9166  O O   . TYR C 1 354 ? 92.376  139.972 86.289  1.00 68.75 ? 354 TYR C O   1 
ATOM   9167  C CB  . TYR C 1 354 ? 92.932  137.276 87.515  1.00 68.75 ? 354 TYR C CB  1 
ATOM   9168  C CG  . TYR C 1 354 ? 92.978  135.774 87.547  1.00 68.75 ? 354 TYR C CG  1 
ATOM   9169  C CD1 . TYR C 1 354 ? 92.863  135.040 86.384  1.00 68.75 ? 354 TYR C CD1 1 
ATOM   9170  C CD2 . TYR C 1 354 ? 93.167  135.092 88.733  1.00 68.75 ? 354 TYR C CD2 1 
ATOM   9171  C CE1 . TYR C 1 354 ? 92.921  133.669 86.399  1.00 68.75 ? 354 TYR C CE1 1 
ATOM   9172  C CE2 . TYR C 1 354 ? 93.236  133.720 88.758  1.00 68.75 ? 354 TYR C CE2 1 
ATOM   9173  C CZ  . TYR C 1 354 ? 93.108  133.013 87.583  1.00 68.75 ? 354 TYR C CZ  1 
ATOM   9174  O OH  . TYR C 1 354 ? 93.167  131.641 87.582  1.00 68.75 ? 354 TYR C OH  1 
ATOM   9175  N N   . LEU C 1 355 ? 91.471  140.107 88.349  1.00 67.41 ? 355 LEU C N   1 
ATOM   9176  C CA  . LEU C 1 355 ? 91.942  141.459 88.602  1.00 67.41 ? 355 LEU C CA  1 
ATOM   9177  C C   . LEU C 1 355 ? 92.986  141.393 89.703  1.00 67.41 ? 355 LEU C C   1 
ATOM   9178  O O   . LEU C 1 355 ? 92.699  140.901 90.802  1.00 67.41 ? 355 LEU C O   1 
ATOM   9179  C CB  . LEU C 1 355 ? 90.801  142.387 89.001  1.00 67.41 ? 355 LEU C CB  1 
ATOM   9180  C CG  . LEU C 1 355 ? 89.732  142.635 87.947  1.00 67.41 ? 355 LEU C CG  1 
ATOM   9181  C CD1 . LEU C 1 355 ? 89.049  143.956 88.221  1.00 67.41 ? 355 LEU C CD1 1 
ATOM   9182  C CD2 . LEU C 1 355 ? 90.328  142.620 86.564  1.00 67.41 ? 355 LEU C CD2 1 
ATOM   9183  N N   . THR C 1 356 ? 94.195  141.866 89.409  1.00 65.82 ? 356 THR C N   1 
ATOM   9184  C CA  . THR C 1 356 ? 95.226  141.912 90.428  1.00 65.82 ? 356 THR C CA  1 
ATOM   9185  C C   . THR C 1 356 ? 95.010  143.119 91.330  1.00 65.82 ? 356 THR C C   1 
ATOM   9186  O O   . THR C 1 356 ? 94.845  144.243 90.851  1.00 65.82 ? 356 THR C O   1 
ATOM   9187  C CB  . THR C 1 356 ? 96.599  141.970 89.778  1.00 65.82 ? 356 THR C CB  1 
ATOM   9188  O OG1 . THR C 1 356 ? 96.708  140.909 88.827  1.00 65.82 ? 356 THR C OG1 1 
ATOM   9189  C CG2 . THR C 1 356 ? 97.680  141.819 90.818  1.00 65.82 ? 356 THR C CG2 1 
ATOM   9190  N N   . VAL C 1 357 ? 94.998  142.881 92.640  1.00 67.34 ? 357 VAL C N   1 
ATOM   9191  C CA  . VAL C 1 357 ? 94.744  143.912 93.635  1.00 67.34 ? 357 VAL C CA  1 
ATOM   9192  C C   . VAL C 1 357 ? 95.868  143.973 94.662  1.00 67.34 ? 357 VAL C C   1 
ATOM   9193  O O   . VAL C 1 357 ? 95.652  144.368 95.804  1.00 67.34 ? 357 VAL C O   1 
ATOM   9194  C CB  . VAL C 1 357 ? 93.382  143.695 94.319  1.00 67.34 ? 357 VAL C CB  1 
ATOM   9195  C CG1 . VAL C 1 357 ? 92.283  143.727 93.293  1.00 67.34 ? 357 VAL C CG1 1 
ATOM   9196  C CG2 . VAL C 1 357 ? 93.361  142.381 95.061  1.00 67.34 ? 357 VAL C CG2 1 
ATOM   9197  N N   . ILE C 1 358 ? 97.076  143.584 94.259  1.00 70.04 ? 358 ILE C N   1 
ATOM   9198  C CA  . ILE C 1 358 ? 98.196  143.525 95.187  1.00 70.04 ? 358 ILE C CA  1 
ATOM   9199  C C   . ILE C 1 358 ? 98.488  144.886 95.798  1.00 70.04 ? 358 ILE C C   1 
ATOM   9200  O O   . ILE C 1 358 ? 99.018  144.974 96.912  1.00 70.04 ? 358 ILE C O   1 
ATOM   9201  C CB  . ILE C 1 358 ? 99.431  142.949 94.469  1.00 70.04 ? 358 ILE C CB  1 
ATOM   9202  C CG1 . ILE C 1 358 ? 100.615 142.841 95.425  1.00 70.04 ? 358 ILE C CG1 1 
ATOM   9203  C CG2 . ILE C 1 358 ? 99.781  143.780 93.261  1.00 70.04 ? 358 ILE C CG2 1 
ATOM   9204  C CD1 . ILE C 1 358 ? 101.770 142.079 94.863  1.00 70.04 ? 358 ILE C CD1 1 
ATOM   9205  N N   . GLU C 1 359 ? 98.139  145.966 95.102  1.00 75.76 ? 359 GLU C N   1 
ATOM   9206  C CA  . GLU C 1 359 ? 98.550  147.304 95.504  1.00 75.76 ? 359 GLU C CA  1 
ATOM   9207  C C   . GLU C 1 359 ? 97.366  148.199 95.823  1.00 75.76 ? 359 GLU C C   1 
ATOM   9208  O O   . GLU C 1 359 ? 97.336  149.352 95.391  1.00 75.76 ? 359 GLU C O   1 
ATOM   9209  C CB  . GLU C 1 359 ? 99.398  147.945 94.409  1.00 75.76 ? 359 GLU C CB  1 
ATOM   9210  C CG  . GLU C 1 359 ? 100.674 147.199 94.077  1.00 75.76 ? 359 GLU C CG  1 
ATOM   9211  C CD  . GLU C 1 359 ? 101.907 147.877 94.634  1.00 75.76 ? 359 GLU C CD  1 
ATOM   9212  O OE1 . GLU C 1 359 ? 101.762 148.725 95.542  1.00 75.76 ? 359 GLU C OE1 1 
ATOM   9213  O OE2 . GLU C 1 359 ? 103.019 147.570 94.153  1.00 75.76 ? 359 GLU C OE2 1 
ATOM   9214  N N   . ASP C 1 360 ? 96.389  147.698 96.564  1.00 78.46 ? 360 ASP C N   1 
ATOM   9215  C CA  . ASP C 1 360 ? 95.166  148.436 96.815  1.00 78.46 ? 360 ASP C CA  1 
ATOM   9216  C C   . ASP C 1 360 ? 94.868  148.499 98.312  1.00 78.46 ? 360 ASP C C   1 
ATOM   9217  O O   . ASP C 1 360 ? 95.605  147.971 99.146  1.00 78.46 ? 360 ASP C O   1 
ATOM   9218  C CB  . ASP C 1 360 ? 94.014  147.798 96.043  1.00 78.46 ? 360 ASP C CB  1 
ATOM   9219  C CG  . ASP C 1 360 ? 94.170  147.943 94.547  1.00 78.46 ? 360 ASP C CG  1 
ATOM   9220  O OD1 . ASP C 1 360 ? 94.809  148.920 94.108  1.00 78.46 ? 360 ASP C OD1 1 
ATOM   9221  O OD2 . ASP C 1 360 ? 93.652  147.087 93.805  1.00 78.46 ? 360 ASP C OD2 1 
ATOM   9222  N N   . TYR C 1 361 ? 93.763  149.158 98.653  1.00 80.71 ? 361 TYR C N   1 
ATOM   9223  C CA  . TYR C 1 361 ? 93.332  149.275 100.040 1.00 80.71 ? 361 TYR C CA  1 
ATOM   9224  C C   . TYR C 1 361 ? 92.640  147.995 100.479 1.00 80.71 ? 361 TYR C C   1 
ATOM   9225  O O   . TYR C 1 361 ? 91.548  147.682 99.994  1.00 80.71 ? 361 TYR C O   1 
ATOM   9226  C CB  . TYR C 1 361 ? 92.382  150.454 100.213 1.00 80.71 ? 361 TYR C CB  1 
ATOM   9227  C CG  . TYR C 1 361 ? 93.068  151.779 100.325 1.00 80.71 ? 361 TYR C CG  1 
ATOM   9228  C CD1 . TYR C 1 361 ? 93.535  152.230 101.545 1.00 80.71 ? 361 TYR C CD1 1 
ATOM   9229  C CD2 . TYR C 1 361 ? 93.253  152.580 99.214  1.00 80.71 ? 361 TYR C CD2 1 
ATOM   9230  C CE1 . TYR C 1 361 ? 94.167  153.439 101.659 1.00 80.71 ? 361 TYR C CE1 1 
ATOM   9231  C CE2 . TYR C 1 361 ? 93.882  153.798 99.318  1.00 80.71 ? 361 TYR C CE2 1 
ATOM   9232  C CZ  . TYR C 1 361 ? 94.341  154.221 100.544 1.00 80.71 ? 361 TYR C CZ  1 
ATOM   9233  O OH  . TYR C 1 361 ? 94.972  155.435 100.665 1.00 80.71 ? 361 TYR C OH  1 
ATOM   9234  N N   . ASP C 1 362 ? 93.265  147.263 101.406 1.00 75.18 ? 362 ASP C N   1 
ATOM   9235  C CA  . ASP C 1 362 ? 92.610  146.087 101.958 1.00 75.18 ? 362 ASP C CA  1 
ATOM   9236  C C   . ASP C 1 362 ? 91.219  146.424 102.449 1.00 75.18 ? 362 ASP C C   1 
ATOM   9237  O O   . ASP C 1 362 ? 90.302  145.615 102.306 1.00 75.18 ? 362 ASP C O   1 
ATOM   9238  C CB  . ASP C 1 362 ? 93.428  145.490 103.097 1.00 75.18 ? 362 ASP C CB  1 
ATOM   9239  C CG  . ASP C 1 362 ? 94.665  144.791 102.615 1.00 75.18 ? 362 ASP C CG  1 
ATOM   9240  O OD1 . ASP C 1 362 ? 94.693  144.366 101.449 1.00 75.18 ? 362 ASP C OD1 1 
ATOM   9241  O OD2 . ASP C 1 362 ? 95.619  144.667 103.402 1.00 75.18 ? 362 ASP C OD2 1 
ATOM   9242  N N   . ALA C 1 363 ? 91.035  147.613 103.017 1.00 77.85 ? 363 ALA C N   1 
ATOM   9243  C CA  . ALA C 1 363 ? 89.694  148.041 103.385 1.00 77.85 ? 363 ALA C CA  1 
ATOM   9244  C C   . ALA C 1 363 ? 88.807  148.144 102.153 1.00 77.85 ? 363 ALA C C   1 
ATOM   9245  O O   . ALA C 1 363 ? 87.687  147.622 102.134 1.00 77.85 ? 363 ALA C O   1 
ATOM   9246  C CB  . ALA C 1 363 ? 89.751  149.374 104.125 1.00 77.85 ? 363 ALA C CB  1 
ATOM   9247  N N   . TYR C 1 364 ? 89.307  148.789 101.097 1.00 80.08 ? 364 TYR C N   1 
ATOM   9248  C CA  . TYR C 1 364 ? 88.509  148.932 99.883  1.00 80.08 ? 364 TYR C CA  1 
ATOM   9249  C C   . TYR C 1 364 ? 88.321  147.594 99.183  1.00 80.08 ? 364 TYR C C   1 
ATOM   9250  O O   . TYR C 1 364 ? 87.219  147.285 98.718  1.00 80.08 ? 364 TYR C O   1 
ATOM   9251  C CB  . TYR C 1 364 ? 89.161  149.933 98.935  1.00 80.08 ? 364 TYR C CB  1 
ATOM   9252  C CG  . TYR C 1 364 ? 88.884  151.373 99.279  1.00 80.08 ? 364 TYR C CG  1 
ATOM   9253  C CD1 . TYR C 1 364 ? 87.655  151.758 99.787  1.00 80.08 ? 364 TYR C CD1 1 
ATOM   9254  C CD2 . TYR C 1 364 ? 89.854  152.348 99.095  1.00 80.08 ? 364 TYR C CD2 1 
ATOM   9255  C CE1 . TYR C 1 364 ? 87.398  153.071 100.102 1.00 80.08 ? 364 TYR C CE1 1 
ATOM   9256  C CE2 . TYR C 1 364 ? 89.611  153.661 99.410  1.00 80.08 ? 364 TYR C CE2 1 
ATOM   9257  C CZ  . TYR C 1 364 ? 88.380  154.019 99.912  1.00 80.08 ? 364 TYR C CZ  1 
ATOM   9258  O OH  . TYR C 1 364 ? 88.129  155.334 100.227 1.00 80.08 ? 364 TYR C OH  1 
ATOM   9259  N N   . VAL C 1 365 ? 89.388  146.800 99.078  1.00 74.67 ? 365 VAL C N   1 
ATOM   9260  C CA  . VAL C 1 365 ? 89.268  145.487 98.452  1.00 74.67 ? 365 VAL C CA  1 
ATOM   9261  C C   . VAL C 1 365 ? 88.236  144.653 99.191  1.00 74.67 ? 365 VAL C C   1 
ATOM   9262  O O   . VAL C 1 365 ? 87.345  144.052 98.581  1.00 74.67 ? 365 VAL C O   1 
ATOM   9263  C CB  . VAL C 1 365 ? 90.632  144.780 98.413  1.00 74.67 ? 365 VAL C CB  1 
ATOM   9264  C CG1 . VAL C 1 365 ? 90.481  143.406 97.821  1.00 74.67 ? 365 VAL C CG1 1 
ATOM   9265  C CG2 . VAL C 1 365 ? 91.622  145.584 97.618  1.00 74.67 ? 365 VAL C CG2 1 
ATOM   9266  N N   . SER C 1 366 ? 88.342  144.610 100.518 1.00 73.78 ? 366 SER C N   1 
ATOM   9267  C CA  . SER C 1 366 ? 87.383  143.869 101.321 1.00 73.78 ? 366 SER C CA  1 
ATOM   9268  C C   . SER C 1 366 ? 85.975  144.396 101.122 1.00 73.78 ? 366 SER C C   1 
ATOM   9269  O O   . SER C 1 366 ? 85.029  143.614 101.016 1.00 73.78 ? 366 SER C O   1 
ATOM   9270  C CB  . SER C 1 366 ? 87.758  143.949 102.793 1.00 73.78 ? 366 SER C CB  1 
ATOM   9271  O OG  . SER C 1 366 ? 89.018  143.360 103.022 1.00 73.78 ? 366 SER C OG  1 
ATOM   9272  N N   . SER C 1 367 ? 85.809  145.719 101.085 1.00 76.71 ? 367 SER C N   1 
ATOM   9273  C CA  . SER C 1 367 ? 84.475  146.278 100.922 1.00 76.71 ? 367 SER C CA  1 
ATOM   9274  C C   . SER C 1 367 ? 83.878  145.871 99.587  1.00 76.71 ? 367 SER C C   1 
ATOM   9275  O O   . SER C 1 367 ? 82.697  145.515 99.504  1.00 76.71 ? 367 SER C O   1 
ATOM   9276  C CB  . SER C 1 367 ? 84.526  147.796 101.047 1.00 76.71 ? 367 SER C CB  1 
ATOM   9277  O OG  . SER C 1 367 ? 83.219  148.336 101.100 1.00 76.71 ? 367 SER C OG  1 
ATOM   9278  N N   . ALA C 1 368 ? 84.690  145.901 98.532  1.00 75.97 ? 368 ALA C N   1 
ATOM   9279  C CA  . ALA C 1 368 ? 84.207  145.487 97.223  1.00 75.97 ? 368 ALA C CA  1 
ATOM   9280  C C   . ALA C 1 368 ? 83.849  144.010 97.215  1.00 75.97 ? 368 ALA C C   1 
ATOM   9281  O O   . ALA C 1 368 ? 82.833  143.610 96.637  1.00 75.97 ? 368 ALA C O   1 
ATOM   9282  C CB  . ALA C 1 368 ? 85.253  145.790 96.156  1.00 75.97 ? 368 ALA C CB  1 
ATOM   9283  N N   . ILE C 1 369 ? 84.666  143.180 97.859  1.00 74.94 ? 369 ILE C N   1 
ATOM   9284  C CA  . ILE C 1 369 ? 84.357  141.756 97.906  1.00 74.94 ? 369 ILE C CA  1 
ATOM   9285  C C   . ILE C 1 369 ? 83.042  141.531 98.635  1.00 74.94 ? 369 ILE C C   1 
ATOM   9286  O O   . ILE C 1 369 ? 82.156  140.814 98.154  1.00 74.94 ? 369 ILE C O   1 
ATOM   9287  C CB  . ILE C 1 369 ? 85.505  140.971 98.560  1.00 74.94 ? 369 ILE C CB  1 
ATOM   9288  C CG1 . ILE C 1 369 ? 86.777  141.101 97.733  1.00 74.94 ? 369 ILE C CG1 1 
ATOM   9289  C CG2 . ILE C 1 369 ? 85.129  139.517 98.676  1.00 74.94 ? 369 ILE C CG2 1 
ATOM   9290  C CD1 . ILE C 1 369 ? 87.932  140.320 98.288  1.00 74.94 ? 369 ILE C CD1 1 
ATOM   9291  N N   . VAL C 1 370 ? 82.880  142.168 99.792  1.00 76.40 ? 370 VAL C N   1 
ATOM   9292  C CA  . VAL C 1 370 ? 81.710  141.884 100.606 1.00 76.40 ? 370 VAL C CA  1 
ATOM   9293  C C   . VAL C 1 370 ? 80.448  142.442 99.962  1.00 76.40 ? 370 VAL C C   1 
ATOM   9294  O O   . VAL C 1 370 ? 79.385  141.819 100.036 1.00 76.40 ? 370 VAL C O   1 
ATOM   9295  C CB  . VAL C 1 370 ? 81.903  142.395 102.044 1.00 76.40 ? 370 VAL C CB  1 
ATOM   9296  C CG1 . VAL C 1 370 ? 83.194  141.862 102.617 1.00 76.40 ? 370 VAL C CG1 1 
ATOM   9297  C CG2 . VAL C 1 370 ? 81.876  143.900 102.093 1.00 76.40 ? 370 VAL C CG2 1 
ATOM   9298  N N   . ASP C 1 371 ? 80.530  143.588 99.279  1.00 79.49 ? 371 ASP C N   1 
ATOM   9299  C CA  . ASP C 1 371 ? 79.286  144.083 98.701  1.00 79.49 ? 371 ASP C CA  1 
ATOM   9300  C C   . ASP C 1 371 ? 78.983  143.435 97.353  1.00 79.49 ? 371 ASP C C   1 
ATOM   9301  O O   . ASP C 1 371 ? 77.812  143.318 96.981  1.00 79.49 ? 371 ASP C O   1 
ATOM   9302  C CB  . ASP C 1 371 ? 79.291  145.610 98.603  1.00 79.49 ? 371 ASP C CB  1 
ATOM   9303  C CG  . ASP C 1 371 ? 80.337  146.142 97.663  1.00 79.49 ? 371 ASP C CG  1 
ATOM   9304  O OD1 . ASP C 1 371 ? 81.149  145.350 97.175  1.00 79.49 ? 371 ASP C OD1 1 
ATOM   9305  O OD2 . ASP C 1 371 ? 80.345  147.367 97.410  1.00 79.49 ? 371 ASP C OD2 1 
ATOM   9306  N N   . LEU C 1 372 ? 79.981  142.829 96.669  1.00 79.46 ? 372 LEU C N   1 
ATOM   9307  C CA  . LEU C 1 372 ? 79.731  142.043 95.429  1.00 79.46 ? 372 LEU C CA  1 
ATOM   9308  C C   . LEU C 1 372 ? 79.120  140.750 95.828  1.00 79.46 ? 372 LEU C C   1 
ATOM   9309  O O   . LEU C 1 372 ? 78.158  140.283 95.237  1.00 79.46 ? 372 LEU C O   1 
ATOM   9310  C CB  . LEU C 1 372 ? 81.050  141.671 94.802  1.00 79.46 ? 372 LEU C CB  1 
ATOM   9311  C CG  . LEU C 1 372 ? 81.084  140.703 93.614  1.00 79.46 ? 372 LEU C CG  1 
ATOM   9312  C CD1 . LEU C 1 372 ? 80.441  141.311 92.378  1.00 79.46 ? 372 LEU C CD1 1 
ATOM   9313  C CD2 . LEU C 1 372 ? 82.510  140.271 93.317  1.00 79.46 ? 372 LEU C CD2 1 
ATOM   9314  N N   . PHE C 1 373 ? 79.712  140.147 96.839  1.00 78.29 ? 373 PHE C N   1 
ATOM   9315  C CA  . PHE C 1 373 ? 79.207  138.930 97.354  1.00 78.29 ? 373 PHE C CA  1 
ATOM   9316  C C   . PHE C 1 373 ? 77.852  139.326 97.794  1.00 78.29 ? 373 PHE C C   1 
ATOM   9317  O O   . PHE C 1 373 ? 76.903  138.621 97.513  1.00 78.29 ? 373 PHE C O   1 
ATOM   9318  C CB  . PHE C 1 373 ? 79.931  138.643 98.613  1.00 78.29 ? 373 PHE C CB  1 
ATOM   9319  C CG  . PHE C 1 373 ? 81.053  137.682 98.476  1.00 78.29 ? 373 PHE C CG  1 
ATOM   9320  C CD1 . PHE C 1 373 ? 81.447  137.232 97.248  1.00 78.29 ? 373 PHE C CD1 1 
ATOM   9321  C CD2 . PHE C 1 373 ? 81.711  137.232 99.598  1.00 78.29 ? 373 PHE C CD2 1 
ATOM   9322  C CE1 . PHE C 1 373 ? 82.482  136.340 97.139  1.00 78.29 ? 373 PHE C CE1 1 
ATOM   9323  C CE2 . PHE C 1 373 ? 82.745  136.343 99.501  1.00 78.29 ? 373 PHE C CE2 1 
ATOM   9324  C CZ  . PHE C 1 373 ? 83.137  135.896 98.267  1.00 78.29 ? 373 PHE C CZ  1 
ATOM   9325  N N   . THR C 1 374 ? 77.714  140.436 98.505  1.00 80.40 ? 374 THR C N   1 
ATOM   9326  C CA  . THR C 1 374 ? 76.397  140.753 99.009  1.00 80.40 ? 374 THR C CA  1 
ATOM   9327  C C   . THR C 1 374 ? 75.494  141.027 97.852  1.00 80.40 ? 374 THR C C   1 
ATOM   9328  O O   . THR C 1 374 ? 74.287  140.955 97.963  1.00 80.40 ? 374 THR C O   1 
ATOM   9329  C CB  . THR C 1 374 ? 76.387  141.819 100.100 1.00 80.40 ? 374 THR C CB  1 
ATOM   9330  O OG1 . THR C 1 374 ? 77.041  141.295 101.259 1.00 80.40 ? 374 THR C OG1 1 
ATOM   9331  C CG2 . THR C 1 374 ? 74.976  142.242 100.512 1.00 80.40 ? 374 THR C CG2 1 
ATOM   9332  N N   . GLY C 1 375 ? 76.045  141.332 96.709  1.00 83.59 ? 375 GLY C N   1 
ATOM   9333  C CA  . GLY C 1 375 ? 75.173  141.434 95.541  1.00 83.59 ? 375 GLY C CA  1 
ATOM   9334  C C   . GLY C 1 375 ? 74.581  140.094 95.104  1.00 83.59 ? 375 GLY C C   1 
ATOM   9335  O O   . GLY C 1 375 ? 73.385  140.003 94.840  1.00 83.59 ? 375 GLY C O   1 
ATOM   9336  N N   . LEU C 1 376 ? 75.404  139.039 95.081  1.00 81.24 ? 376 LEU C N   1 
ATOM   9337  C CA  . LEU C 1 376 ? 74.930  137.701 94.735  1.00 81.24 ? 376 LEU C CA  1 
ATOM   9338  C C   . LEU C 1 376 ? 73.901  137.286 95.729  1.00 81.24 ? 376 LEU C C   1 
ATOM   9339  O O   . LEU C 1 376 ? 72.924  136.625 95.402  1.00 81.24 ? 376 LEU C O   1 
ATOM   9340  C CB  . LEU C 1 376 ? 76.055  136.696 94.788  1.00 81.24 ? 376 LEU C CB  1 
ATOM   9341  C CG  . LEU C 1 376 ? 76.990  136.541 93.587  1.00 81.24 ? 376 LEU C CG  1 
ATOM   9342  C CD1 . LEU C 1 376 ? 76.255  136.804 92.281  1.00 81.24 ? 376 LEU C CD1 1 
ATOM   9343  C CD2 . LEU C 1 376 ? 78.227  137.415 93.700  1.00 81.24 ? 376 LEU C CD2 1 
ATOM   9344  N N   . GLY C 1 377 ? 74.102  137.687 96.960  1.00 79.41 ? 377 GLY C N   1 
ATOM   9345  C CA  . GLY C 1 377 ? 73.197  137.281 97.986  1.00 79.41 ? 377 GLY C CA  1 
ATOM   9346  C C   . GLY C 1 377 ? 73.962  136.272 98.763  1.00 79.41 ? 377 GLY C C   1 
ATOM   9347  O O   . GLY C 1 377 ? 73.394  135.555 99.576  1.00 79.41 ? 377 GLY C O   1 
ATOM   9348  N N   . TRP C 1 378 ? 75.258  136.204 98.535  1.00 75.89 ? 378 TRP C N   1 
ATOM   9349  C CA  . TRP C 1 378 ? 76.035  135.193 99.212  1.00 75.89 ? 378 TRP C CA  1 
ATOM   9350  C C   . TRP C 1 378 ? 76.333  135.650 100.631 1.00 75.89 ? 378 TRP C C   1 
ATOM   9351  O O   . TRP C 1 378 ? 77.478  135.950 100.910 1.00 75.89 ? 378 TRP C O   1 
ATOM   9352  C CB  . TRP C 1 378 ? 77.377  134.990 98.525  1.00 75.89 ? 378 TRP C CB  1 
ATOM   9353  C CG  . TRP C 1 378 ? 77.357  134.114 97.311  1.00 75.89 ? 378 TRP C CG  1 
ATOM   9354  C CD1 . TRP C 1 378 ? 76.298  133.414 96.816  1.00 75.89 ? 378 TRP C CD1 1 
ATOM   9355  C CD2 . TRP C 1 378 ? 78.459  133.840 96.437  1.00 75.89 ? 378 TRP C CD2 1 
ATOM   9356  N NE1 . TRP C 1 378 ? 76.671  132.727 95.689  1.00 75.89 ? 378 TRP C NE1 1 
ATOM   9357  C CE2 . TRP C 1 378 ? 77.994  132.976 95.436  1.00 75.89 ? 378 TRP C CE2 1 
ATOM   9358  C CE3 . TRP C 1 378 ? 79.793  134.244 96.404  1.00 75.89 ? 378 TRP C CE3 1 
ATOM   9359  C CZ2 . TRP C 1 378 ? 78.817  132.517 94.412  1.00 75.89 ? 378 TRP C CZ2 1 
ATOM   9360  C CZ3 . TRP C 1 378 ? 80.603  133.780 95.392  1.00 75.89 ? 378 TRP C CZ3 1 
ATOM   9361  C CH2 . TRP C 1 378 ? 80.116  132.927 94.415  1.00 75.89 ? 378 TRP C CH2 1 
ATOM   9362  N N   . ALA C 1 379 ? 75.351  135.664 101.546 1.00 75.14 ? 379 ALA C N   1 
ATOM   9363  C CA  . ALA C 1 379 ? 75.574  136.185 102.899 1.00 75.14 ? 379 ALA C CA  1 
ATOM   9364  C C   . ALA C 1 379 ? 76.279  135.206 103.767 1.00 75.14 ? 379 ALA C C   1 
ATOM   9365  O O   . ALA C 1 379 ? 77.173  135.542 104.512 1.00 75.14 ? 379 ALA C O   1 
ATOM   9366  C CB  . ALA C 1 379 ? 74.293  136.574 103.535 1.00 75.14 ? 379 ALA C CB  1 
ATOM   9367  N N   . ALA C 1 380 ? 75.827  133.981 103.751 1.00 74.27 ? 380 ALA C N   1 
ATOM   9368  C CA  . ALA C 1 380 ? 76.626  132.995 104.463 1.00 74.27 ? 380 ALA C CA  1 
ATOM   9369  C C   . ALA C 1 380 ? 78.088  133.130 104.076 1.00 74.27 ? 380 ALA C C   1 
ATOM   9370  O O   . ALA C 1 380 ? 78.978  133.148 104.932 1.00 74.27 ? 380 ALA C O   1 
ATOM   9371  C CB  . ALA C 1 380 ? 76.113  131.590 104.160 1.00 74.27 ? 380 ALA C CB  1 
ATOM   9372  N N   . HIS C 1 381 ? 78.348  133.255 102.778 1.00 73.61 ? 381 HIS C N   1 
ATOM   9373  C CA  . HIS C 1 381 ? 79.705  133.503 102.324 1.00 73.61 ? 381 HIS C CA  1 
ATOM   9374  C C   . HIS C 1 381 ? 80.234  134.831 102.841 1.00 73.61 ? 381 HIS C C   1 
ATOM   9375  O O   . HIS C 1 381 ? 81.440  134.969 103.053 1.00 73.61 ? 381 HIS C O   1 
ATOM   9376  C CB  . HIS C 1 381 ? 79.753  133.468 100.803 1.00 73.61 ? 381 HIS C CB  1 
ATOM   9377  C CG  . HIS C 1 381 ? 79.496  132.114 100.222 1.00 73.61 ? 381 HIS C CG  1 
ATOM   9378  N ND1 . HIS C 1 381 ? 80.443  131.113 100.215 1.00 73.61 ? 381 HIS C ND1 1 
ATOM   9379  C CD2 . HIS C 1 381 ? 78.401  131.598 99.616  1.00 73.61 ? 381 HIS C CD2 1 
ATOM   9380  C CE1 . HIS C 1 381 ? 79.945  130.041 99.628  1.00 73.61 ? 381 HIS C CE1 1 
ATOM   9381  N NE2 . HIS C 1 381 ? 78.708  130.309 99.256  1.00 73.61 ? 381 HIS C NE2 1 
ATOM   9382  N N   . VAL C 1 382 ? 79.358  135.813 103.061 1.00 73.75 ? 382 VAL C N   1 
ATOM   9383  C CA  . VAL C 1 382 ? 79.810  137.102 103.579 1.00 73.75 ? 382 VAL C CA  1 
ATOM   9384  C C   . VAL C 1 382 ? 80.368  136.942 104.986 1.00 73.75 ? 382 VAL C C   1 
ATOM   9385  O O   . VAL C 1 382 ? 81.478  137.398 105.292 1.00 73.75 ? 382 VAL C O   1 
ATOM   9386  C CB  . VAL C 1 382 ? 78.667  138.134 103.553 1.00 73.75 ? 382 VAL C CB  1 
ATOM   9387  C CG1 . VAL C 1 382 ? 79.016  139.320 104.430 1.00 73.75 ? 382 VAL C CG1 1 
ATOM   9388  C CG2 . VAL C 1 382 ? 78.383  138.594 102.145 1.00 73.75 ? 382 VAL C CG2 1 
ATOM   9389  N N   . GLN C 1 383 ? 79.586  136.326 105.872 1.00 72.27 ? 383 GLN C N   1 
ATOM   9390  C CA  . GLN C 1 383 ? 80.073  136.082 107.223 1.00 72.27 ? 383 GLN C CA  1 
ATOM   9391  C C   . GLN C 1 383 ? 81.304  135.201 107.193 1.00 72.27 ? 383 GLN C C   1 
ATOM   9392  O O   . GLN C 1 383 ? 82.246  135.415 107.959 1.00 72.27 ? 383 GLN C O   1 
ATOM   9393  C CB  . GLN C 1 383 ? 78.985  135.444 108.081 1.00 72.27 ? 383 GLN C CB  1 
ATOM   9394  C CG  . GLN C 1 383 ? 77.678  136.205 108.078 1.00 72.27 ? 383 GLN C CG  1 
ATOM   9395  C CD  . GLN C 1 383 ? 77.876  137.686 108.301 1.00 72.27 ? 383 GLN C CD  1 
ATOM   9396  O OE1 . GLN C 1 383 ? 78.515  138.100 109.265 1.00 72.27 ? 383 GLN C OE1 1 
ATOM   9397  N NE2 . GLN C 1 383 ? 77.335  138.496 107.401 1.00 72.27 ? 383 GLN C NE2 1 
ATOM   9398  N N   . THR C 1 384 ? 81.311  134.203 106.312 1.00 68.29 ? 384 THR C N   1 
ATOM   9399  C CA  . THR C 1 384 ? 82.491  133.371 106.142 1.00 68.29 ? 384 THR C CA  1 
ATOM   9400  C C   . THR C 1 384 ? 83.713  134.226 105.849 1.00 68.29 ? 384 THR C C   1 
ATOM   9401  O O   . THR C 1 384 ? 84.762  134.082 106.488 1.00 68.29 ? 384 THR C O   1 
ATOM   9402  C CB  . THR C 1 384 ? 82.255  132.379 105.009 1.00 68.29 ? 384 THR C CB  1 
ATOM   9403  O OG1 . THR C 1 384 ? 80.884  131.974 105.011 1.00 68.29 ? 384 THR C OG1 1 
ATOM   9404  C CG2 . THR C 1 384 ? 83.119  131.161 105.202 1.00 68.29 ? 384 THR C CG2 1 
ATOM   9405  N N   . HIS C 1 385 ? 83.581  135.141 104.893 1.00 66.87 ? 385 HIS C N   1 
ATOM   9406  C CA  . HIS C 1 385 ? 84.711  135.954 104.477 1.00 66.87 ? 385 HIS C CA  1 
ATOM   9407  C C   . HIS C 1 385 ? 85.195  136.843 105.610 1.00 66.87 ? 385 HIS C C   1 
ATOM   9408  O O   . HIS C 1 385 ? 86.395  136.916 105.886 1.00 66.87 ? 385 HIS C O   1 
ATOM   9409  C CB  . HIS C 1 385 ? 84.326  136.796 103.270 1.00 66.87 ? 385 HIS C CB  1 
ATOM   9410  C CG  . HIS C 1 385 ? 85.430  137.677 102.797 1.00 66.87 ? 385 HIS C CG  1 
ATOM   9411  N ND1 . HIS C 1 385 ? 85.404  139.044 102.943 1.00 66.87 ? 385 HIS C ND1 1 
ATOM   9412  C CD2 . HIS C 1 385 ? 86.612  137.381 102.209 1.00 66.87 ? 385 HIS C CD2 1 
ATOM   9413  C CE1 . HIS C 1 385 ? 86.517  139.556 102.452 1.00 66.87 ? 385 HIS C CE1 1 
ATOM   9414  N NE2 . HIS C 1 385 ? 87.268  138.568 102.001 1.00 66.87 ? 385 HIS C NE2 1 
ATOM   9415  N N   . LYS C 1 386 ? 84.269  137.532 106.278 1.00 68.34 ? 386 LYS C N   1 
ATOM   9416  C CA  . LYS C 1 386 ? 84.668  138.437 107.353 1.00 68.34 ? 386 LYS C CA  1 
ATOM   9417  C C   . LYS C 1 386 ? 85.276  137.674 108.521 1.00 68.34 ? 386 LYS C C   1 
ATOM   9418  O O   . LYS C 1 386 ? 86.217  138.151 109.166 1.00 68.34 ? 386 LYS C O   1 
ATOM   9419  C CB  . LYS C 1 386 ? 83.471  139.260 107.820 1.00 68.34 ? 386 LYS C CB  1 
ATOM   9420  C CG  . LYS C 1 386 ? 83.226  140.507 107.007 1.00 68.34 ? 386 LYS C CG  1 
ATOM   9421  C CD  . LYS C 1 386 ? 81.776  140.922 107.091 1.00 68.34 ? 386 LYS C CD  1 
ATOM   9422  C CE  . LYS C 1 386 ? 81.650  142.424 107.153 1.00 68.34 ? 386 LYS C CE  1 
ATOM   9423  N NZ  . LYS C 1 386 ? 82.405  142.960 108.313 1.00 68.34 ? 386 LYS C NZ  1 
ATOM   9424  N N   . LYS C 1 387 ? 84.747  136.489 108.813 1.00 62.80 ? 387 LYS C N   1 
ATOM   9425  C CA  . LYS C 1 387 ? 85.303  135.670 109.877 1.00 62.80 ? 387 LYS C CA  1 
ATOM   9426  C C   . LYS C 1 387 ? 86.729  135.263 109.554 1.00 62.80 ? 387 LYS C C   1 
ATOM   9427  O O   . LYS C 1 387 ? 87.637  135.425 110.378 1.00 62.80 ? 387 LYS C O   1 
ATOM   9428  C CB  . LYS C 1 387 ? 84.421  134.444 110.081 1.00 62.80 ? 387 LYS C CB  1 
ATOM   9429  C CG  . LYS C 1 387 ? 85.005  133.396 110.978 1.00 62.80 ? 387 LYS C CG  1 
ATOM   9430  C CD  . LYS C 1 387 ? 84.295  132.082 110.775 1.00 62.80 ? 387 LYS C CD  1 
ATOM   9431  C CE  . LYS C 1 387 ? 82.797  132.271 110.743 1.00 62.80 ? 387 LYS C CE  1 
ATOM   9432  N NZ  . LYS C 1 387 ? 82.087  130.971 110.659 1.00 62.80 ? 387 LYS C NZ  1 
ATOM   9433  N N   . ILE C 1 388 ? 86.939  134.711 108.358 1.00 60.47 ? 388 ILE C N   1 
ATOM   9434  C CA  . ILE C 1 388 ? 88.287  134.342 107.944 1.00 60.47 ? 388 ILE C CA  1 
ATOM   9435  C C   . ILE C 1 388 ? 89.195  135.557 107.979 1.00 60.47 ? 388 ILE C C   1 
ATOM   9436  O O   . ILE C 1 388 ? 90.371  135.464 108.343 1.00 60.47 ? 388 ILE C O   1 
ATOM   9437  C CB  . ILE C 1 388 ? 88.259  133.696 106.550 1.00 60.47 ? 388 ILE C CB  1 
ATOM   9438  C CG1 . ILE C 1 388 ? 87.352  132.476 106.564 1.00 60.47 ? 388 ILE C CG1 1 
ATOM   9439  C CG2 . ILE C 1 388 ? 89.649  133.297 106.126 1.00 60.47 ? 388 ILE C CG2 1 
ATOM   9440  C CD1 . ILE C 1 388 ? 87.192  131.822 105.233 1.00 60.47 ? 388 ILE C CD1 1 
ATOM   9441  N N   . GLU C 1 389 ? 88.654  136.720 107.630 1.00 64.47 ? 389 GLU C N   1 
ATOM   9442  C CA  . GLU C 1 389 ? 89.437  137.944 107.659 1.00 64.47 ? 389 GLU C CA  1 
ATOM   9443  C C   . GLU C 1 389 ? 89.929  138.237 109.066 1.00 64.47 ? 389 GLU C C   1 
ATOM   9444  O O   . GLU C 1 389 ? 91.134  138.228 109.334 1.00 64.47 ? 389 GLU C O   1 
ATOM   9445  C CB  . GLU C 1 389 ? 88.589  139.098 107.137 1.00 64.47 ? 389 GLU C CB  1 
ATOM   9446  C CG  . GLU C 1 389 ? 89.389  140.196 106.495 1.00 64.47 ? 389 GLU C CG  1 
ATOM   9447  C CD  . GLU C 1 389 ? 88.516  141.337 106.058 1.00 64.47 ? 389 GLU C CD  1 
ATOM   9448  O OE1 . GLU C 1 389 ? 87.534  141.632 106.768 1.00 64.47 ? 389 GLU C OE1 1 
ATOM   9449  O OE2 . GLU C 1 389 ? 88.803  141.929 105.000 1.00 64.47 ? 389 GLU C OE2 1 
ATOM   9450  N N   . LYS C 1 390 ? 88.993  138.468 109.985 1.00 63.76 ? 390 LYS C N   1 
ATOM   9451  C CA  . LYS C 1 390 ? 89.350  138.852 111.345 1.00 63.76 ? 390 LYS C CA  1 
ATOM   9452  C C   . LYS C 1 390 ? 90.265  137.826 111.995 1.00 63.76 ? 390 LYS C C   1 
ATOM   9453  O O   . LYS C 1 390 ? 91.265  138.186 112.623 1.00 63.76 ? 390 LYS C O   1 
ATOM   9454  C CB  . LYS C 1 390 ? 88.085  139.042 112.175 1.00 63.76 ? 390 LYS C CB  1 
ATOM   9455  C CG  . LYS C 1 390 ? 88.342  139.479 113.592 1.00 63.76 ? 390 LYS C CG  1 
ATOM   9456  C CD  . LYS C 1 390 ? 87.046  139.596 114.364 1.00 63.76 ? 390 LYS C CD  1 
ATOM   9457  C CE  . LYS C 1 390 ? 86.322  138.265 114.401 1.00 63.76 ? 390 LYS C CE  1 
ATOM   9458  N NZ  . LYS C 1 390 ? 85.028  138.350 115.129 1.00 63.76 ? 390 LYS C NZ  1 
ATOM   9459  N N   . GLU C 1 391 ? 89.954  136.542 111.841 1.00 60.87 ? 391 GLU C N   1 
ATOM   9460  C CA  . GLU C 1 391 ? 90.726  135.522 112.536 1.00 60.87 ? 391 GLU C CA  1 
ATOM   9461  C C   . GLU C 1 391 ? 92.088  135.312 111.892 1.00 60.87 ? 391 GLU C C   1 
ATOM   9462  O O   . GLU C 1 391 ? 93.115  135.340 112.577 1.00 60.87 ? 391 GLU C O   1 
ATOM   9463  C CB  . GLU C 1 391 ? 89.937  134.215 112.569 1.00 60.87 ? 391 GLU C CB  1 
ATOM   9464  C CG  . GLU C 1 391 ? 88.682  134.293 113.418 1.00 60.87 ? 391 GLU C CG  1 
ATOM   9465  C CD  . GLU C 1 391 ? 87.874  133.018 113.388 1.00 60.87 ? 391 GLU C CD  1 
ATOM   9466  O OE1 . GLU C 1 391 ? 87.981  132.269 112.399 1.00 60.87 ? 391 GLU C OE1 1 
ATOM   9467  O OE2 . GLU C 1 391 ? 87.132  132.761 114.355 1.00 60.87 ? 391 GLU C OE2 1 
ATOM   9468  N N   . ALA C 1 392 ? 92.120  135.095 110.580 1.00 57.06 ? 392 ALA C N   1 
ATOM   9469  C CA  . ALA C 1 392 ? 93.363  134.776 109.899 1.00 57.06 ? 392 ALA C CA  1 
ATOM   9470  C C   . ALA C 1 392 ? 94.178  136.006 109.545 1.00 57.06 ? 392 ALA C C   1 
ATOM   9471  O O   . ALA C 1 392 ? 95.396  135.892 109.371 1.00 57.06 ? 392 ALA C O   1 
ATOM   9472  C CB  . ALA C 1 392 ? 93.073  133.979 108.632 1.00 57.06 ? 392 ALA C CB  1 
ATOM   9473  N N   . TYR C 1 393 ? 93.546  137.174 109.437 1.00 58.07 ? 393 TYR C N   1 
ATOM   9474  C CA  . TYR C 1 393 ? 94.227  138.403 109.038 1.00 58.07 ? 393 TYR C CA  1 
ATOM   9475  C C   . TYR C 1 393 ? 93.787  139.538 109.949 1.00 58.07 ? 393 TYR C C   1 
ATOM   9476  O O   . TYR C 1 393 ? 92.831  140.263 109.646 1.00 58.07 ? 393 TYR C O   1 
ATOM   9477  C CB  . TYR C 1 393 ? 93.947  138.725 107.577 1.00 58.07 ? 393 TYR C CB  1 
ATOM   9478  C CG  . TYR C 1 393 ? 94.398  137.629 106.655 1.00 58.07 ? 393 TYR C CG  1 
ATOM   9479  C CD1 . TYR C 1 393 ? 95.744  137.397 106.436 1.00 58.07 ? 393 TYR C CD1 1 
ATOM   9480  C CD2 . TYR C 1 393 ? 93.480  136.810 106.019 1.00 58.07 ? 393 TYR C CD2 1 
ATOM   9481  C CE1 . TYR C 1 393 ? 96.162  136.396 105.604 1.00 58.07 ? 393 TYR C CE1 1 
ATOM   9482  C CE2 . TYR C 1 393 ? 93.894  135.802 105.186 1.00 58.07 ? 393 TYR C CE2 1 
ATOM   9483  C CZ  . TYR C 1 393 ? 95.234  135.604 104.986 1.00 58.07 ? 393 TYR C CZ  1 
ATOM   9484  O OH  . TYR C 1 393 ? 95.653  134.605 104.156 1.00 58.07 ? 393 TYR C OH  1 
ATOM   9485  N N   . PRO C 1 394 ? 94.466  139.732 111.062 1.00 65.79 ? 394 PRO C N   1 
ATOM   9486  C CA  . PRO C 1 394 ? 94.093  140.823 111.965 1.00 65.79 ? 394 PRO C CA  1 
ATOM   9487  C C   . PRO C 1 394 ? 94.463  142.189 111.413 1.00 65.79 ? 394 PRO C C   1 
ATOM   9488  O O   . PRO C 1 394 ? 93.819  143.188 111.745 1.00 65.79 ? 394 PRO C O   1 
ATOM   9489  C CB  . PRO C 1 394 ? 94.883  140.501 113.236 1.00 65.79 ? 394 PRO C CB  1 
ATOM   9490  C CG  . PRO C 1 394 ? 96.068  139.744 112.753 1.00 65.79 ? 394 PRO C CG  1 
ATOM   9491  C CD  . PRO C 1 394 ? 95.616  138.960 111.564 1.00 65.79 ? 394 PRO C CD  1 
ATOM   9492  N N   . MET C 1 395 ? 95.493  142.231 110.563 1.00 65.49 ? 395 MET C N   1 
ATOM   9493  C CA  . MET C 1 395 ? 96.081  143.498 110.134 1.00 65.49 ? 395 MET C CA  1 
ATOM   9494  C C   . MET C 1 395 ? 95.052  144.431 109.513 1.00 65.49 ? 395 MET C C   1 
ATOM   9495  O O   . MET C 1 395 ? 95.107  145.646 109.718 1.00 65.49 ? 395 MET C O   1 
ATOM   9496  C CB  . MET C 1 395 ? 97.217  143.231 109.151 1.00 65.49 ? 395 MET C CB  1 
ATOM   9497  C CG  . MET C 1 395 ? 96.867  142.229 108.069 1.00 65.49 ? 395 MET C CG  1 
ATOM   9498  S SD  . MET C 1 395 ? 98.291  141.269 107.538 1.00 65.49 ? 395 MET C SD  1 
ATOM   9499  C CE  . MET C 1 395 ? 98.572  140.267 108.986 1.00 65.49 ? 395 MET C CE  1 
ATOM   9500  N N   . CYS C 1 396 ? 94.098  143.883 108.760 1.00 70.88 ? 396 CYS C N   1 
ATOM   9501  C CA  . CYS C 1 396 ? 93.121  144.720 108.070 1.00 70.88 ? 396 CYS C CA  1 
ATOM   9502  C C   . CYS C 1 396 ? 92.317  145.585 109.030 1.00 70.88 ? 396 CYS C C   1 
ATOM   9503  O O   . CYS C 1 396 ? 91.709  146.571 108.600 1.00 70.88 ? 396 CYS C O   1 
ATOM   9504  C CB  . CYS C 1 396 ? 92.178  143.852 107.235 1.00 70.88 ? 396 CYS C CB  1 
ATOM   9505  S SG  . CYS C 1 396 ? 91.254  142.627 108.187 1.00 70.88 ? 396 CYS C SG  1 
ATOM   9506  N N   . ASP C 1 397 ? 92.296  145.236 110.313 1.00 74.38 ? 397 ASP C N   1 
ATOM   9507  C CA  . ASP C 1 397 ? 91.665  146.047 111.341 1.00 74.38 ? 397 ASP C CA  1 
ATOM   9508  C C   . ASP C 1 397 ? 92.676  146.779 112.202 1.00 74.38 ? 397 ASP C C   1 
ATOM   9509  O O   . ASP C 1 397 ? 92.453  147.937 112.557 1.00 74.38 ? 397 ASP C O   1 
ATOM   9510  C CB  . ASP C 1 397 ? 90.778  145.176 112.230 1.00 74.38 ? 397 ASP C CB  1 
ATOM   9511  C CG  . ASP C 1 397 ? 89.652  144.531 111.463 1.00 74.38 ? 397 ASP C CG  1 
ATOM   9512  O OD1 . ASP C 1 397 ? 89.560  144.773 110.245 1.00 74.38 ? 397 ASP C OD1 1 
ATOM   9513  O OD2 . ASP C 1 397 ? 88.862  143.781 112.069 1.00 74.38 ? 397 ASP C OD2 1 
ATOM   9514  N N   . ALA C 1 398 ? 93.790  146.128 112.539 1.00 75.00 ? 398 ALA C N   1 
ATOM   9515  C CA  . ALA C 1 398 ? 94.812  146.784 113.346 1.00 75.00 ? 398 ALA C CA  1 
ATOM   9516  C C   . ALA C 1 398 ? 95.426  147.971 112.620 1.00 75.00 ? 398 ALA C C   1 
ATOM   9517  O O   . ALA C 1 398 ? 95.968  148.877 113.260 1.00 75.00 ? 398 ALA C O   1 
ATOM   9518  C CB  . ALA C 1 398 ? 95.900  145.784 113.732 1.00 75.00 ? 398 ALA C CB  1 
ATOM   9519  N N   . ASN C 1 399 ? 95.356  147.985 111.293 1.00 76.35 ? 399 ASN C N   1 
ATOM   9520  C CA  . ASN C 1 399 ? 95.923  149.054 110.486 1.00 76.35 ? 399 ASN C CA  1 
ATOM   9521  C C   . ASN C 1 399 ? 94.849  149.584 109.548 1.00 76.35 ? 399 ASN C C   1 
ATOM   9522  O O   . ASN C 1 399 ? 94.339  148.821 108.710 1.00 76.35 ? 399 ASN C O   1 
ATOM   9523  C CB  . ASN C 1 399 ? 97.125  148.543 109.693 1.00 76.35 ? 399 ASN C CB  1 
ATOM   9524  C CG  . ASN C 1 399 ? 97.963  149.656 109.117 1.00 76.35 ? 399 ASN C CG  1 
ATOM   9525  O OD1 . ASN C 1 399 ? 97.467  150.745 108.840 1.00 76.35 ? 399 ASN C OD1 1 
ATOM   9526  N ND2 . ASN C 1 399 ? 99.247  149.385 108.926 1.00 76.35 ? 399 ASN C ND2 1 
ATOM   9527  N N   . PRO C 1 400 ? 94.457  150.854 109.649 1.00 77.39 ? 400 PRO C N   1 
ATOM   9528  C CA  . PRO C 1 400 ? 93.498  151.391 108.670 1.00 77.39 ? 400 PRO C CA  1 
ATOM   9529  C C   . PRO C 1 400 ? 94.044  151.390 107.257 1.00 77.39 ? 400 PRO C C   1 
ATOM   9530  O O   . PRO C 1 400 ? 93.315  151.070 106.312 1.00 77.39 ? 400 PRO C O   1 
ATOM   9531  C CB  . PRO C 1 400 ? 93.239  152.815 109.178 1.00 77.39 ? 400 PRO C CB  1 
ATOM   9532  C CG  . PRO C 1 400 ? 93.661  152.796 110.609 1.00 77.39 ? 400 PRO C CG  1 
ATOM   9533  C CD  . PRO C 1 400 ? 94.797  151.836 110.687 1.00 77.39 ? 400 PRO C CD  1 
ATOM   9534  N N   . GLN C 1 401 ? 95.315  151.742 107.091 1.00 77.67 ? 401 GLN C N   1 
ATOM   9535  C CA  . GLN C 1 401 ? 95.978  151.702 105.792 1.00 77.67 ? 401 GLN C CA  1 
ATOM   9536  C C   . GLN C 1 401 ? 96.655  150.350 105.653 1.00 77.67 ? 401 GLN C C   1 
ATOM   9537  O O   . GLN C 1 401 ? 97.770  150.150 106.134 1.00 77.67 ? 401 GLN C O   1 
ATOM   9538  C CB  . GLN C 1 401 ? 96.991  152.831 105.664 1.00 77.67 ? 401 GLN C CB  1 
ATOM   9539  C CG  . GLN C 1 401 ? 96.410  154.219 105.813 1.00 77.67 ? 401 GLN C CG  1 
ATOM   9540  C CD  . GLN C 1 401 ? 97.480  155.283 105.781 1.00 77.67 ? 401 GLN C CD  1 
ATOM   9541  O OE1 . GLN C 1 401 ? 97.207  156.463 105.990 1.00 77.67 ? 401 GLN C OE1 1 
ATOM   9542  N NE2 . GLN C 1 401 ? 98.713  154.870 105.516 1.00 77.67 ? 401 GLN C NE2 1 
ATOM   9543  N N   . SER C 1 402 ? 95.986  149.421 104.978 1.00 75.00 ? 402 SER C N   1 
ATOM   9544  C CA  . SER C 1 402 ? 96.470  148.056 104.846 1.00 75.00 ? 402 SER C CA  1 
ATOM   9545  C C   . SER C 1 402 ? 96.302  147.595 103.410 1.00 75.00 ? 402 SER C C   1 
ATOM   9546  O O   . SER C 1 402 ? 95.287  147.889 102.774 1.00 75.00 ? 402 SER C O   1 
ATOM   9547  C CB  . SER C 1 402 ? 95.722  147.127 105.796 1.00 75.00 ? 402 SER C CB  1 
ATOM   9548  O OG  . SER C 1 402 ? 94.340  147.141 105.506 1.00 75.00 ? 402 SER C OG  1 
ATOM   9549  N N   . THR C 1 403 ? 97.305  146.873 102.903 1.00 69.99 ? 403 THR C N   1 
ATOM   9550  C CA  . THR C 1 403 ? 97.342  146.492 101.498 1.00 69.99 ? 403 THR C CA  1 
ATOM   9551  C C   . THR C 1 403 ? 97.671  145.020 101.289 1.00 69.99 ? 403 THR C C   1 
ATOM   9552  O O   . THR C 1 403 ? 97.812  144.591 100.139 1.00 69.99 ? 403 THR C O   1 
ATOM   9553  C CB  . THR C 1 403 ? 98.369  147.338 100.738 1.00 69.99 ? 403 THR C CB  1 
ATOM   9554  O OG1 . THR C 1 403 ? 99.681  147.037 101.224 1.00 69.99 ? 403 THR C OG1 1 
ATOM   9555  C CG2 . THR C 1 403 ? 98.095  148.811 100.921 1.00 69.99 ? 403 THR C CG2 1 
ATOM   9556  N N   . HIS C 1 404 ? 97.781  144.232 102.356 1.00 61.80 ? 404 HIS C N   1 
ATOM   9557  C CA  . HIS C 1 404 ? 98.546  142.997 102.314 1.00 61.80 ? 404 HIS C CA  1 
ATOM   9558  C C   . HIS C 1 404 ? 97.735  141.721 102.458 1.00 61.80 ? 404 HIS C C   1 
ATOM   9559  O O   . HIS C 1 404 ? 98.317  140.635 102.399 1.00 61.80 ? 404 HIS C O   1 
ATOM   9560  C CB  . HIS C 1 404 ? 99.622  143.034 103.398 1.00 61.80 ? 404 HIS C CB  1 
ATOM   9561  C CG  . HIS C 1 404 ? 100.793 143.882 103.034 1.00 61.80 ? 404 HIS C CG  1 
ATOM   9562  N ND1 . HIS C 1 404 ? 100.978 144.374 101.761 1.00 61.80 ? 404 HIS C ND1 1 
ATOM   9563  C CD2 . HIS C 1 404 ? 101.838 144.327 103.767 1.00 61.80 ? 404 HIS C CD2 1 
ATOM   9564  C CE1 . HIS C 1 404 ? 102.089 145.086 101.725 1.00 61.80 ? 404 HIS C CE1 1 
ATOM   9565  N NE2 . HIS C 1 404 ? 102.630 145.073 102.929 1.00 61.80 ? 404 HIS C NE2 1 
ATOM   9566  N N   . ALA C 1 405 ? 96.421  141.799 102.631 1.00 60.04 ? 405 ALA C N   1 
ATOM   9567  C CA  . ALA C 1 405 ? 95.649  140.568 102.713 1.00 60.04 ? 405 ALA C CA  1 
ATOM   9568  C C   . ALA C 1 405 ? 95.479  139.942 101.340 1.00 60.04 ? 405 ALA C C   1 
ATOM   9569  O O   . ALA C 1 405 ? 95.957  138.834 101.089 1.00 60.04 ? 405 ALA C O   1 
ATOM   9570  C CB  . ALA C 1 405 ? 94.287  140.834 103.350 1.00 60.04 ? 405 ALA C CB  1 
ATOM   9571  N N   . TYR C 1 406 ? 94.822  140.649 100.434 1.00 63.98 ? 406 TYR C N   1 
ATOM   9572  C CA  . TYR C 1 406 ? 94.409  140.101 99.153  1.00 63.98 ? 406 TYR C CA  1 
ATOM   9573  C C   . TYR C 1 406 ? 95.449  140.368 98.079  1.00 63.98 ? 406 TYR C C   1 
ATOM   9574  O O   . TYR C 1 406 ? 96.178  141.360 98.137  1.00 63.98 ? 406 TYR C O   1 
ATOM   9575  C CB  . TYR C 1 406 ? 93.074  140.695 98.733  1.00 63.98 ? 406 TYR C CB  1 
ATOM   9576  C CG  . TYR C 1 406 ? 92.074  140.677 99.843  1.00 63.98 ? 406 TYR C CG  1 
ATOM   9577  C CD1 . TYR C 1 406 ? 91.300  139.558 100.080 1.00 63.98 ? 406 TYR C CD1 1 
ATOM   9578  C CD2 . TYR C 1 406 ? 91.915  141.770 100.674 1.00 63.98 ? 406 TYR C CD2 1 
ATOM   9579  C CE1 . TYR C 1 406 ? 90.385  139.530 101.102 1.00 63.98 ? 406 TYR C CE1 1 
ATOM   9580  C CE2 . TYR C 1 406 ? 91.005  141.749 101.701 1.00 63.98 ? 406 TYR C CE2 1 
ATOM   9581  C CZ  . TYR C 1 406 ? 90.240  140.625 101.910 1.00 63.98 ? 406 TYR C CZ  1 
ATOM   9582  O OH  . TYR C 1 406 ? 89.325  140.586 102.931 1.00 63.98 ? 406 TYR C OH  1 
ATOM   9583  N N   . VAL C 1 407 ? 95.525  139.460 97.105  1.00 59.46 ? 407 VAL C N   1 
ATOM   9584  C CA  . VAL C 1 407 ? 96.376  139.623 95.940  1.00 59.46 ? 407 VAL C CA  1 
ATOM   9585  C C   . VAL C 1 407 ? 95.588  139.569 94.638  1.00 59.46 ? 407 VAL C C   1 
ATOM   9586  O O   . VAL C 1 407 ? 95.852  140.350 93.725  1.00 59.46 ? 407 VAL C O   1 
ATOM   9587  C CB  . VAL C 1 407 ? 97.532  138.602 95.932  1.00 59.46 ? 407 VAL C CB  1 
ATOM   9588  C CG1 . VAL C 1 407 ? 98.344  138.729 97.200  1.00 59.46 ? 407 VAL C CG1 1 
ATOM   9589  C CG2 . VAL C 1 407 ? 97.005  137.212 95.832  1.00 59.46 ? 407 VAL C CG2 1 
ATOM   9590  N N   . TRP C 1 408 ? 94.615  138.668 94.524  1.00 56.74 ? 408 TRP C N   1 
ATOM   9591  C CA  . TRP C 1 408 ? 93.868  138.514 93.285  1.00 56.74 ? 408 TRP C CA  1 
ATOM   9592  C C   . TRP C 1 408 ? 92.394  138.315 93.576  1.00 56.74 ? 408 TRP C C   1 
ATOM   9593  O O   . TRP C 1 408 ? 92.025  137.605 94.513  1.00 56.74 ? 408 TRP C O   1 
ATOM   9594  C CB  . TRP C 1 408 ? 94.390  137.331 92.460  1.00 56.74 ? 408 TRP C CB  1 
ATOM   9595  C CG  . TRP C 1 408 ? 95.784  137.508 92.053  1.00 56.74 ? 408 TRP C CG  1 
ATOM   9596  C CD1 . TRP C 1 408 ? 96.293  138.566 91.401  1.00 56.74 ? 408 TRP C CD1 1 
ATOM   9597  C CD2 . TRP C 1 408 ? 96.872  136.614 92.284  1.00 56.74 ? 408 TRP C CD2 1 
ATOM   9598  N NE1 . TRP C 1 408 ? 97.634  138.403 91.202  1.00 56.74 ? 408 TRP C NE1 1 
ATOM   9599  C CE2 . TRP C 1 408 ? 98.015  137.207 91.739  1.00 56.74 ? 408 TRP C CE2 1 
ATOM   9600  C CE3 . TRP C 1 408 ? 96.990  135.370 92.890  1.00 56.74 ? 408 TRP C CE3 1 
ATOM   9601  C CZ2 . TRP C 1 408 ? 99.262  136.604 91.785  1.00 56.74 ? 408 TRP C CZ2 1 
ATOM   9602  C CZ3 . TRP C 1 408 ? 98.231  134.776 92.939  1.00 56.74 ? 408 TRP C CZ3 1 
ATOM   9603  C CH2 . TRP C 1 408 ? 99.348  135.390 92.388  1.00 56.74 ? 408 TRP C CH2 1 
ATOM   9604  N N   . ILE C 1 409 ? 91.555  138.936 92.756  1.00 62.47 ? 409 ILE C N   1 
ATOM   9605  C CA  . ILE C 1 409 ? 90.117  138.700 92.774  1.00 62.47 ? 409 ILE C CA  1 
ATOM   9606  C C   . ILE C 1 409 ? 89.759  138.096 91.428  1.00 62.47 ? 409 ILE C C   1 
ATOM   9607  O O   . ILE C 1 409 ? 89.803  138.788 90.401  1.00 62.47 ? 409 ILE C O   1 
ATOM   9608  C CB  . ILE C 1 409 ? 89.316  139.983 93.024  1.00 62.47 ? 409 ILE C CB  1 
ATOM   9609  C CG1 . ILE C 1 409 ? 90.038  140.884 94.021  1.00 62.47 ? 409 ILE C CG1 1 
ATOM   9610  C CG2 . ILE C 1 409 ? 87.941  139.643 93.537  1.00 62.47 ? 409 ILE C CG2 1 
ATOM   9611  C CD1 . ILE C 1 409 ? 90.136  140.294 95.397  1.00 62.47 ? 409 ILE C CD1 1 
ATOM   9612  N N   . SER C 1 410 ? 89.419  136.812 91.412  1.00 64.75 ? 410 SER C N   1 
ATOM   9613  C CA  . SER C 1 410 ? 89.220  136.113 90.154  1.00 64.75 ? 410 SER C CA  1 
ATOM   9614  C C   . SER C 1 410 ? 87.751  135.798 89.935  1.00 64.75 ? 410 SER C C   1 
ATOM   9615  O O   . SER C 1 410 ? 87.037  135.410 90.867  1.00 64.75 ? 410 SER C O   1 
ATOM   9616  C CB  . SER C 1 410 ? 90.040  134.833 90.110  1.00 64.75 ? 410 SER C CB  1 
ATOM   9617  O OG  . SER C 1 410 ? 89.852  134.160 88.886  1.00 64.75 ? 410 SER C OG  1 
ATOM   9618  N N   . LEU C 1 411 ? 87.321  135.954 88.689  1.00 67.97 ? 411 LEU C N   1 
ATOM   9619  C CA  . LEU C 1 411 ? 85.949  135.755 88.265  1.00 67.97 ? 411 LEU C CA  1 
ATOM   9620  C C   . LEU C 1 411 ? 85.900  134.747 87.128  1.00 67.97 ? 411 LEU C C   1 
ATOM   9621  O O   . LEU C 1 411 ? 86.839  134.627 86.341  1.00 67.97 ? 411 LEU C O   1 
ATOM   9622  C CB  . LEU C 1 411 ? 85.326  137.066 87.792  1.00 67.97 ? 411 LEU C CB  1 
ATOM   9623  C CG  . LEU C 1 411 ? 85.288  138.225 88.780  1.00 67.97 ? 411 LEU C CG  1 
ATOM   9624  C CD1 . LEU C 1 411 ? 86.581  139.014 88.753  1.00 67.97 ? 411 LEU C CD1 1 
ATOM   9625  C CD2 . LEU C 1 411 ? 84.122  139.110 88.445  1.00 67.97 ? 411 LEU C CD2 1 
ATOM   9626  N N   . ALA C 1 412 ? 84.797  134.010 87.064  1.00 70.81 ? 412 ALA C N   1 
ATOM   9627  C CA  . ALA C 1 412 ? 84.461  133.175 85.923  1.00 70.81 ? 412 ALA C CA  1 
ATOM   9628  C C   . ALA C 1 412 ? 83.042  132.690 86.118  1.00 70.81 ? 412 ALA C C   1 
ATOM   9629  O O   . ALA C 1 412 ? 82.691  132.241 87.207  1.00 70.81 ? 412 ALA C O   1 
ATOM   9630  C CB  . ALA C 1 412 ? 85.405  131.980 85.783  1.00 70.81 ? 412 ALA C CB  1 
ATOM   9631  N N   . TYR C 1 413 ? 82.233  132.777 85.072  1.00 81.39 ? 413 TYR C N   1 
ATOM   9632  C CA  . TYR C 1 413 ? 80.852  132.327 85.135  1.00 81.39 ? 413 TYR C CA  1 
ATOM   9633  C C   . TYR C 1 413 ? 80.733  131.025 84.364  1.00 81.39 ? 413 TYR C C   1 
ATOM   9634  O O   . TYR C 1 413 ? 80.939  131.000 83.147  1.00 81.39 ? 413 TYR C O   1 
ATOM   9635  C CB  . TYR C 1 413 ? 79.895  133.373 84.572  1.00 81.39 ? 413 TYR C CB  1 
ATOM   9636  C CG  . TYR C 1 413 ? 78.515  133.305 85.181  1.00 81.39 ? 413 TYR C CG  1 
ATOM   9637  C CD1 . TYR C 1 413 ? 77.667  132.249 84.903  1.00 81.39 ? 413 TYR C CD1 1 
ATOM   9638  C CD2 . TYR C 1 413 ? 78.061  134.299 86.034  1.00 81.39 ? 413 TYR C CD2 1 
ATOM   9639  C CE1 . TYR C 1 413 ? 76.407  132.182 85.459  1.00 81.39 ? 413 TYR C CE1 1 
ATOM   9640  C CE2 . TYR C 1 413 ? 76.801  134.241 86.594  1.00 81.39 ? 413 TYR C CE2 1 
ATOM   9641  C CZ  . TYR C 1 413 ? 75.981  133.180 86.303  1.00 81.39 ? 413 TYR C CZ  1 
ATOM   9642  O OH  . TYR C 1 413 ? 74.727  133.118 86.854  1.00 81.39 ? 413 TYR C OH  1 
ATOM   9643  N N   . LYS C 1 414 ? 80.408  129.954 85.070  1.00 80.35 ? 414 LYS C N   1 
ATOM   9644  C CA  . LYS C 1 414 ? 80.228  128.644 84.472  1.00 80.35 ? 414 LYS C CA  1 
ATOM   9645  C C   . LYS C 1 414 ? 78.741  128.382 84.304  1.00 80.35 ? 414 LYS C C   1 
ATOM   9646  O O   . LYS C 1 414 ? 77.914  129.279 84.467  1.00 80.35 ? 414 LYS C O   1 
ATOM   9647  C CB  . LYS C 1 414 ? 80.931  127.574 85.306  1.00 80.35 ? 414 LYS C CB  1 
ATOM   9648  C CG  . LYS C 1 414 ? 82.430  127.582 85.073  1.00 80.35 ? 414 LYS C CG  1 
ATOM   9649  C CD  . LYS C 1 414 ? 83.196  126.697 86.026  1.00 80.35 ? 414 LYS C CD  1 
ATOM   9650  C CE  . LYS C 1 414 ? 84.684  126.765 85.715  1.00 80.35 ? 414 LYS C CE  1 
ATOM   9651  N NZ  . LYS C 1 414 ? 85.527  126.123 86.756  1.00 80.35 ? 414 LYS C NZ  1 
ATOM   9652  N N   . LYS C 1 415 ? 78.405  127.139 83.955  1.00 89.97 ? 415 LYS C N   1 
ATOM   9653  C CA  . LYS C 1 415 ? 77.070  126.852 83.439  1.00 89.97 ? 415 LYS C CA  1 
ATOM   9654  C C   . LYS C 1 415 ? 75.982  127.196 84.450  1.00 89.97 ? 415 LYS C C   1 
ATOM   9655  O O   . LYS C 1 415 ? 74.830  127.441 84.072  1.00 89.97 ? 415 LYS C O   1 
ATOM   9656  C CB  . LYS C 1 415 ? 76.976  125.386 83.018  1.00 89.97 ? 415 LYS C CB  1 
ATOM   9657  C CG  . LYS C 1 415 ? 75.718  125.030 82.230  1.00 89.97 ? 415 LYS C CG  1 
ATOM   9658  C CD  . LYS C 1 415 ? 74.613  124.482 83.112  1.00 89.97 ? 415 LYS C CD  1 
ATOM   9659  C CE  . LYS C 1 415 ? 74.950  123.101 83.637  1.00 89.97 ? 415 LYS C CE  1 
ATOM   9660  N NZ  . LYS C 1 415 ? 73.848  122.558 84.483  1.00 89.97 ? 415 LYS C NZ  1 
ATOM   9661  N N   . THR C 1 416 ? 76.322  127.240 85.736  1.00 85.53 ? 416 THR C N   1 
ATOM   9662  C CA  . THR C 1 416 ? 75.351  127.596 86.763  1.00 85.53 ? 416 THR C CA  1 
ATOM   9663  C C   . THR C 1 416 ? 75.670  128.908 87.459  1.00 85.53 ? 416 THR C C   1 
ATOM   9664  O O   . THR C 1 416 ? 74.836  129.815 87.476  1.00 85.53 ? 416 THR C O   1 
ATOM   9665  C CB  . THR C 1 416 ? 75.245  126.480 87.805  1.00 85.53 ? 416 THR C CB  1 
ATOM   9666  O OG1 . THR C 1 416 ? 74.784  125.285 87.169  1.00 85.53 ? 416 THR C OG1 1 
ATOM   9667  C CG2 . THR C 1 416 ? 74.267  126.881 88.893  1.00 85.53 ? 416 THR C CG2 1 
ATOM   9668  N N   . GLY C 1 417 ? 76.859  129.042 88.038  1.00 79.87 ? 417 GLY C N   1 
ATOM   9669  C CA  . GLY C 1 417 ? 77.187  130.218 88.808  1.00 79.87 ? 417 GLY C CA  1 
ATOM   9670  C C   . GLY C 1 417 ? 78.588  130.736 88.568  1.00 79.87 ? 417 GLY C C   1 
ATOM   9671  O O   . GLY C 1 417 ? 79.391  130.130 87.852  1.00 79.87 ? 417 GLY C O   1 
ATOM   9672  N N   . PRO C 1 418 ? 78.902  131.883 89.163  1.00 74.26 ? 418 PRO C N   1 
ATOM   9673  C CA  . PRO C 1 418 ? 80.244  132.447 89.027  1.00 74.26 ? 418 PRO C CA  1 
ATOM   9674  C C   . PRO C 1 418 ? 81.267  131.639 89.802  1.00 74.26 ? 418 PRO C C   1 
ATOM   9675  O O   . PRO C 1 418 ? 80.955  130.850 90.694  1.00 74.26 ? 418 PRO C O   1 
ATOM   9676  C CB  . PRO C 1 418 ? 80.107  133.855 89.608  1.00 74.26 ? 418 PRO C CB  1 
ATOM   9677  C CG  . PRO C 1 418 ? 78.654  134.124 89.641  1.00 74.26 ? 418 PRO C CG  1 
ATOM   9678  C CD  . PRO C 1 418 ? 77.992  132.806 89.854  1.00 74.26 ? 418 PRO C CD  1 
ATOM   9679  N N   . TYR C 1 419 ? 82.520  131.869 89.453  1.00 67.61 ? 419 TYR C N   1 
ATOM   9680  C CA  . TYR C 1 419 ? 83.649  131.210 90.095  1.00 67.61 ? 419 TYR C CA  1 
ATOM   9681  C C   . TYR C 1 419 ? 84.540  132.331 90.596  1.00 67.61 ? 419 TYR C C   1 
ATOM   9682  O O   . TYR C 1 419 ? 85.559  132.655 89.986  1.00 67.61 ? 419 TYR C O   1 
ATOM   9683  C CB  . TYR C 1 419 ? 84.350  130.312 89.103  1.00 67.61 ? 419 TYR C CB  1 
ATOM   9684  C CG  . TYR C 1 419 ? 85.337  129.336 89.671  1.00 67.61 ? 419 TYR C CG  1 
ATOM   9685  C CD1 . TYR C 1 419 ? 86.651  129.709 89.915  1.00 67.61 ? 419 TYR C CD1 1 
ATOM   9686  C CD2 . TYR C 1 419 ? 84.968  128.025 89.922  1.00 67.61 ? 419 TYR C CD2 1 
ATOM   9687  C CE1 . TYR C 1 419 ? 87.564  128.802 90.418  1.00 67.61 ? 419 TYR C CE1 1 
ATOM   9688  C CE2 . TYR C 1 419 ? 85.869  127.118 90.420  1.00 67.61 ? 419 TYR C CE2 1 
ATOM   9689  C CZ  . TYR C 1 419 ? 87.164  127.509 90.668  1.00 67.61 ? 419 TYR C CZ  1 
ATOM   9690  O OH  . TYR C 1 419 ? 88.054  126.594 91.173  1.00 67.61 ? 419 TYR C OH  1 
ATOM   9691  N N   . ILE C 1 420 ? 84.169  132.897 91.736  1.00 63.30 ? 420 ILE C N   1 
ATOM   9692  C CA  . ILE C 1 420 ? 84.887  134.013 92.331  1.00 63.30 ? 420 ILE C CA  1 
ATOM   9693  C C   . ILE C 1 420 ? 85.799  133.445 93.394  1.00 63.30 ? 420 ILE C C   1 
ATOM   9694  O O   . ILE C 1 420 ? 85.334  132.856 94.375  1.00 63.30 ? 420 ILE C O   1 
ATOM   9695  C CB  . ILE C 1 420 ? 83.933  135.052 92.932  1.00 63.30 ? 420 ILE C CB  1 
ATOM   9696  C CG1 . ILE C 1 420 ? 82.933  135.524 91.885  1.00 63.30 ? 420 ILE C CG1 1 
ATOM   9697  C CG2 . ILE C 1 420 ? 84.721  136.218 93.473  1.00 63.30 ? 420 ILE C CG2 1 
ATOM   9698  C CD1 . ILE C 1 420 ? 82.132  136.714 92.315  1.00 63.30 ? 420 ILE C CD1 1 
ATOM   9699  N N   . THR C 1 421 ? 87.091  133.606 93.198  1.00 57.11 ? 421 THR C N   1 
ATOM   9700  C CA  . THR C 1 421 ? 88.072  133.106 94.138  1.00 57.11 ? 421 THR C CA  1 
ATOM   9701  C C   . THR C 1 421 ? 88.933  134.254 94.627  1.00 57.11 ? 421 THR C C   1 
ATOM   9702  O O   . THR C 1 421 ? 89.447  135.049 93.831  1.00 57.11 ? 421 THR C O   1 
ATOM   9703  C CB  . THR C 1 421 ? 88.887  131.974 93.518  1.00 57.11 ? 421 THR C CB  1 
ATOM   9704  O OG1 . THR C 1 421 ? 90.117  131.786 94.228  1.00 57.11 ? 421 THR C OG1 1 
ATOM   9705  C CG2 . THR C 1 421 ? 89.090  132.177 92.049  1.00 57.11 ? 421 THR C CG2 1 
ATOM   9706  N N   . VAL C 1 422 ? 89.031  134.352 95.945  1.00 53.58 ? 422 VAL C N   1 
ATOM   9707  C CA  . VAL C 1 422 ? 89.644  135.480 96.625  1.00 53.58 ? 422 VAL C CA  1 
ATOM   9708  C C   . VAL C 1 422 ? 91.003  134.975 97.076  1.00 53.58 ? 422 VAL C C   1 
ATOM   9709  O O   . VAL C 1 422 ? 91.142  134.338 98.113  1.00 53.58 ? 422 VAL C O   1 
ATOM   9710  C CB  . VAL C 1 422 ? 88.788  135.971 97.789  1.00 53.58 ? 422 VAL C CB  1 
ATOM   9711  C CG1 . VAL C 1 422 ? 89.531  136.986 98.598  1.00 53.58 ? 422 VAL C CG1 1 
ATOM   9712  C CG2 . VAL C 1 422 ? 87.500  136.561 97.276  1.00 53.58 ? 422 VAL C CG2 1 
ATOM   9713  N N   . TYR C 1 423 ? 92.014  135.228 96.266  1.00 53.61 ? 423 TYR C N   1 
ATOM   9714  C CA  . TYR C 1 423 ? 93.339  134.758 96.608  1.00 53.61 ? 423 TYR C CA  1 
ATOM   9715  C C   . TYR C 1 423 ? 93.935  135.674 97.652  1.00 53.61 ? 423 TYR C C   1 
ATOM   9716  O O   . TYR C 1 423 ? 93.813  136.895 97.573  1.00 53.61 ? 423 TYR C O   1 
ATOM   9717  C CB  . TYR C 1 423 ? 94.214  134.709 95.365  1.00 53.61 ? 423 TYR C CB  1 
ATOM   9718  C CG  . TYR C 1 423 ? 93.629  133.838 94.288  1.00 53.61 ? 423 TYR C CG  1 
ATOM   9719  C CD1 . TYR C 1 423 ? 92.627  134.297 93.461  1.00 53.61 ? 423 TYR C CD1 1 
ATOM   9720  C CD2 . TYR C 1 423 ? 94.053  132.545 94.128  1.00 53.61 ? 423 TYR C CD2 1 
ATOM   9721  C CE1 . TYR C 1 423 ? 92.094  133.499 92.497  1.00 53.61 ? 423 TYR C CE1 1 
ATOM   9722  C CE2 . TYR C 1 423 ? 93.527  131.739 93.167  1.00 53.61 ? 423 TYR C CE2 1 
ATOM   9723  C CZ  . TYR C 1 423 ? 92.543  132.215 92.355  1.00 53.61 ? 423 TYR C CZ  1 
ATOM   9724  O OH  . TYR C 1 423 ? 92.018  131.396 91.389  1.00 53.61 ? 423 TYR C OH  1 
ATOM   9725  N N   . THR C 1 424 ? 94.556  135.079 98.652  1.00 50.03 ? 424 THR C N   1 
ATOM   9726  C CA  . THR C 1 424 ? 95.156  135.831 99.731  1.00 50.03 ? 424 THR C CA  1 
ATOM   9727  C C   . THR C 1 424 ? 96.632  135.521 99.781  1.00 50.03 ? 424 THR C C   1 
ATOM   9728  O O   . THR C 1 424 ? 97.129  134.628 99.101  1.00 50.03 ? 424 THR C O   1 
ATOM   9729  C CB  . THR C 1 424 ? 94.519  135.499 101.080 1.00 50.03 ? 424 THR C CB  1 
ATOM   9730  O OG1 . THR C 1 424 ? 94.614  134.091 101.311 1.00 50.03 ? 424 THR C OG1 1 
ATOM   9731  C CG2 . THR C 1 424 ? 93.069  135.925 101.113 1.00 50.03 ? 424 THR C CG2 1 
ATOM   9732  N N   . ASN C 1 425 ? 97.330  136.286 100.589 1.00 48.27 ? 425 ASN C N   1 
ATOM   9733  C CA  . ASN C 1 425 ? 98.687  135.930 100.955 1.00 48.27 ? 425 ASN C CA  1 
ATOM   9734  C C   . ASN C 1 425 ? 98.607  135.399 102.367 1.00 48.27 ? 425 ASN C C   1 
ATOM   9735  O O   . ASN C 1 425 ? 98.489  136.185 103.318 1.00 48.27 ? 425 ASN C O   1 
ATOM   9736  C CB  . ASN C 1 425 ? 99.620  137.135 100.876 1.00 48.27 ? 425 ASN C CB  1 
ATOM   9737  C CG  . ASN C 1 425 ? 101.065 136.742 100.909 1.00 48.27 ? 425 ASN C CG  1 
ATOM   9738  O OD1 . ASN C 1 425 ? 101.394 135.563 100.881 1.00 48.27 ? 425 ASN C OD1 1 
ATOM   9739  N ND2 . ASN C 1 425 ? 101.944 137.727 100.961 1.00 48.27 ? 425 ASN C ND2 1 
ATOM   9740  N N   . PRO C 1 426 ? 98.615  134.086 102.568 1.00 48.12 ? 426 PRO C N   1 
ATOM   9741  C CA  . PRO C 1 426 ? 98.640  133.558 103.931 1.00 48.12 ? 426 PRO C CA  1 
ATOM   9742  C C   . PRO C 1 426 ? 99.890  133.938 104.692 1.00 48.12 ? 426 PRO C C   1 
ATOM   9743  O O   . PRO C 1 426 ? 99.968  133.659 105.889 1.00 48.12 ? 426 PRO C O   1 
ATOM   9744  C CB  . PRO C 1 426 ? 98.550  132.047 103.718 1.00 48.12 ? 426 PRO C CB  1 
ATOM   9745  C CG  . PRO C 1 426 ? 99.080  131.836 102.360 1.00 48.12 ? 426 PRO C CG  1 
ATOM   9746  C CD  . PRO C 1 426 ? 98.645  133.014 101.568 1.00 48.12 ? 426 PRO C CD  1 
ATOM   9747  N N   . GLY C 1 427 ? 100.864 134.560 104.044 1.00 48.91 ? 427 GLY C N   1 
ATOM   9748  C CA  . GLY C 1 427 ? 102.054 135.019 104.721 1.00 48.91 ? 427 GLY C CA  1 
ATOM   9749  C C   . GLY C 1 427 ? 102.081 136.523 104.873 1.00 48.91 ? 427 GLY C C   1 
ATOM   9750  O O   . GLY C 1 427 ? 103.149 137.119 105.024 1.00 48.91 ? 427 GLY C O   1 
ATOM   9751  N N   . ALA C 1 428 ? 100.904 137.148 104.825 1.00 51.19 ? 428 ALA C N   1 
ATOM   9752  C CA  . ALA C 1 428 ? 100.831 138.591 104.999 1.00 51.19 ? 428 ALA C CA  1 
ATOM   9753  C C   . ALA C 1 428 ? 101.418 139.017 106.328 1.00 51.19 ? 428 ALA C C   1 
ATOM   9754  O O   . ALA C 1 428 ? 102.045 140.075 106.420 1.00 51.19 ? 428 ALA C O   1 
ATOM   9755  C CB  . ALA C 1 428 ? 99.386  139.057 104.900 1.00 51.19 ? 428 ALA C CB  1 
ATOM   9756  N N   . SER C 1 429 ? 101.231 138.207 107.367 1.00 49.94 ? 429 SER C N   1 
ATOM   9757  C CA  . SER C 1 429 ? 101.795 138.530 108.669 1.00 49.94 ? 429 SER C CA  1 
ATOM   9758  C C   . SER C 1 429 ? 103.303 138.677 108.602 1.00 49.94 ? 429 SER C C   1 
ATOM   9759  O O   . SER C 1 429 ? 103.893 139.356 109.444 1.00 49.94 ? 429 SER C O   1 
ATOM   9760  C CB  . SER C 1 429 ? 101.401 137.463 109.683 1.00 49.94 ? 429 SER C CB  1 
ATOM   9761  O OG  . SER C 1 429 ? 101.933 136.211 109.321 1.00 49.94 ? 429 SER C OG  1 
ATOM   9762  N N   . ILE C 1 430 ? 103.947 138.053 107.616 1.00 49.15 ? 430 ILE C N   1 
ATOM   9763  C CA  . ILE C 1 430 ? 105.377 138.251 107.454 1.00 49.15 ? 430 ILE C CA  1 
ATOM   9764  C C   . ILE C 1 430 ? 105.667 139.650 106.940 1.00 49.15 ? 430 ILE C C   1 
ATOM   9765  O O   . ILE C 1 430 ? 106.757 140.184 107.169 1.00 49.15 ? 430 ILE C O   1 
ATOM   9766  C CB  . ILE C 1 430 ? 105.953 137.191 106.505 1.00 49.15 ? 430 ILE C CB  1 
ATOM   9767  C CG1 . ILE C 1 430 ? 105.530 135.801 106.959 1.00 49.15 ? 430 ILE C CG1 1 
ATOM   9768  C CG2 . ILE C 1 430 ? 107.461 137.251 106.498 1.00 49.15 ? 430 ILE C CG2 1 
ATOM   9769  C CD1 . ILE C 1 430 ? 105.739 134.736 105.926 1.00 49.15 ? 430 ILE C CD1 1 
ATOM   9770  N N   . LEU C 1 431 ? 104.703 140.269 106.263 1.00 52.38 ? 431 LEU C N   1 
ATOM   9771  C CA  . LEU C 1 431 ? 104.870 141.624 105.761 1.00 52.38 ? 431 LEU C CA  1 
ATOM   9772  C C   . LEU C 1 431 ? 104.474 142.673 106.786 1.00 52.38 ? 431 LEU C C   1 
ATOM   9773  O O   . LEU C 1 431 ? 104.139 143.798 106.405 1.00 52.38 ? 431 LEU C O   1 
ATOM   9774  C CB  . LEU C 1 431 ? 104.051 141.811 104.486 1.00 52.38 ? 431 LEU C CB  1 
ATOM   9775  C CG  . LEU C 1 431 ? 104.315 140.771 103.397 1.00 52.38 ? 431 LEU C CG  1 
ATOM   9776  C CD1 . LEU C 1 431 ? 103.600 141.139 102.124 1.00 52.38 ? 431 LEU C CD1 1 
ATOM   9777  C CD2 . LEU C 1 431 ? 105.798 140.634 103.146 1.00 52.38 ? 431 LEU C CD2 1 
ATOM   9778  N N   . GLU C 1 432 ? 104.479 142.325 108.066 1.00 55.09 ? 432 GLU C N   1 
ATOM   9779  C CA  . GLU C 1 432 ? 104.145 143.256 109.128 1.00 55.09 ? 432 GLU C CA  1 
ATOM   9780  C C   . GLU C 1 432 ? 105.160 143.161 110.258 1.00 55.09 ? 432 GLU C C   1 
ATOM   9781  O O   . GLU C 1 432 ? 106.354 143.004 110.016 1.00 55.09 ? 432 GLU C O   1 
ATOM   9782  C CB  . GLU C 1 432 ? 102.742 142.981 109.655 1.00 55.09 ? 432 GLU C CB  1 
ATOM   9783  C CG  . GLU C 1 432 ? 101.687 142.982 108.585 1.00 55.09 ? 432 GLU C CG  1 
ATOM   9784  C CD  . GLU C 1 432 ? 101.517 144.343 107.957 1.00 55.09 ? 432 GLU C CD  1 
ATOM   9785  O OE1 . GLU C 1 432 ? 101.875 145.346 108.604 1.00 55.09 ? 432 GLU C OE1 1 
ATOM   9786  O OE2 . GLU C 1 432 ? 101.031 144.417 106.811 1.00 55.09 ? 432 GLU C OE2 1 
ATOM   9787  N N   . SER D 1 23  ? 137.235 123.390 102.220 1.00 59.15 ? 23  SER D N   1 
ATOM   9788  C CA  . SER D 1 23  ? 137.223 122.578 103.429 1.00 59.15 ? 23  SER D CA  1 
ATOM   9789  C C   . SER D 1 23  ? 136.459 123.284 104.533 1.00 59.15 ? 23  SER D C   1 
ATOM   9790  O O   . SER D 1 23  ? 136.899 124.314 105.036 1.00 59.15 ? 23  SER D O   1 
ATOM   9791  C CB  . SER D 1 23  ? 138.647 122.275 103.891 1.00 59.15 ? 23  SER D CB  1 
ATOM   9792  O OG  . SER D 1 23  ? 139.286 123.449 104.359 1.00 59.15 ? 23  SER D OG  1 
ATOM   9793  N N   . PRO D 1 24  ? 135.312 122.736 104.913 1.00 52.36 ? 24  PRO D N   1 
ATOM   9794  C CA  . PRO D 1 24  ? 134.513 123.370 105.959 1.00 52.36 ? 24  PRO D CA  1 
ATOM   9795  C C   . PRO D 1 24  ? 135.170 123.205 107.317 1.00 52.36 ? 24  PRO D C   1 
ATOM   9796  O O   . PRO D 1 24  ? 136.210 122.562 107.467 1.00 52.36 ? 24  PRO D O   1 
ATOM   9797  C CB  . PRO D 1 24  ? 133.181 122.621 105.891 1.00 52.36 ? 24  PRO D CB  1 
ATOM   9798  C CG  . PRO D 1 24  ? 133.545 121.285 105.376 1.00 52.36 ? 24  PRO D CG  1 
ATOM   9799  C CD  . PRO D 1 24  ? 134.702 121.485 104.436 1.00 52.36 ? 24  PRO D CD  1 
ATOM   9800  N N   . SER D 1 25  ? 134.553 123.810 108.300 1.00 46.44 ? 25  SER D N   1 
ATOM   9801  C CA  . SER D 1 25  ? 134.933 123.619 109.685 1.00 46.44 ? 25  SER D CA  1 
ATOM   9802  C C   . SER D 1 25  ? 133.934 122.699 110.360 1.00 46.44 ? 25  SER D C   1 
ATOM   9803  O O   . SER D 1 25  ? 132.788 122.586 109.920 1.00 46.44 ? 25  SER D O   1 
ATOM   9804  C CB  . SER D 1 25  ? 134.976 124.958 110.404 1.00 46.44 ? 25  SER D CB  1 
ATOM   9805  O OG  . SER D 1 25  ? 133.738 125.624 110.271 1.00 46.44 ? 25  SER D OG  1 
ATOM   9806  N N   . PRO D 1 26  ? 134.342 122.019 111.423 1.00 42.84 ? 26  PRO D N   1 
ATOM   9807  C CA  . PRO D 1 26  ? 133.440 121.079 112.091 1.00 42.84 ? 26  PRO D CA  1 
ATOM   9808  C C   . PRO D 1 26  ? 132.065 121.639 112.376 1.00 42.84 ? 26  PRO D C   1 
ATOM   9809  O O   . PRO D 1 26  ? 131.077 120.943 112.163 1.00 42.84 ? 26  PRO D O   1 
ATOM   9810  C CB  . PRO D 1 26  ? 134.188 120.754 113.380 1.00 42.84 ? 26  PRO D CB  1 
ATOM   9811  C CG  . PRO D 1 26  ? 135.592 120.836 112.987 1.00 42.84 ? 26  PRO D CG  1 
ATOM   9812  C CD  . PRO D 1 26  ? 135.694 121.962 111.999 1.00 42.84 ? 26  PRO D CD  1 
ATOM   9813  N N   . TRP D 1 27  ? 131.956 122.886 112.821 1.00 42.54 ? 27  TRP D N   1 
ATOM   9814  C CA  . TRP D 1 27  ? 130.621 123.400 113.093 1.00 42.54 ? 27  TRP D CA  1 
ATOM   9815  C C   . TRP D 1 27  ? 129.860 123.660 111.802 1.00 42.54 ? 27  TRP D C   1 
ATOM   9816  O O   . TRP D 1 27  ? 128.660 123.395 111.728 1.00 42.54 ? 27  TRP D O   1 
ATOM   9817  C CB  . TRP D 1 27  ? 130.678 124.653 113.968 1.00 42.54 ? 27  TRP D CB  1 
ATOM   9818  C CG  . TRP D 1 27  ? 131.617 125.698 113.550 1.00 42.54 ? 27  TRP D CG  1 
ATOM   9819  C CD1 . TRP D 1 27  ? 131.317 126.840 112.889 1.00 42.54 ? 27  TRP D CD1 1 
ATOM   9820  C CD2 . TRP D 1 27  ? 133.013 125.733 113.801 1.00 42.54 ? 27  TRP D CD2 1 
ATOM   9821  N NE1 . TRP D 1 27  ? 132.446 127.580 112.689 1.00 42.54 ? 27  TRP D NE1 1 
ATOM   9822  C CE2 . TRP D 1 27  ? 133.504 126.920 113.246 1.00 42.54 ? 27  TRP D CE2 1 
ATOM   9823  C CE3 . TRP D 1 27  ? 133.901 124.870 114.436 1.00 42.54 ? 27  TRP D CE3 1 
ATOM   9824  C CZ2 . TRP D 1 27  ? 134.837 127.266 113.302 1.00 42.54 ? 27  TRP D CZ2 1 
ATOM   9825  C CZ3 . TRP D 1 27  ? 135.225 125.212 114.489 1.00 42.54 ? 27  TRP D CZ3 1 
ATOM   9826  C CH2 . TRP D 1 27  ? 135.683 126.399 113.927 1.00 42.54 ? 27  TRP D CH2 1 
ATOM   9827  N N   . ASP D 1 28  ? 130.543 124.134 110.762 1.00 47.11 ? 28  ASP D N   1 
ATOM   9828  C CA  . ASP D 1 28  ? 129.881 124.350 109.481 1.00 47.11 ? 28  ASP D CA  1 
ATOM   9829  C C   . ASP D 1 28  ? 129.370 123.039 108.905 1.00 47.11 ? 28  ASP D C   1 
ATOM   9830  O O   . ASP D 1 28  ? 128.176 122.885 108.621 1.00 47.11 ? 28  ASP D O   1 
ATOM   9831  C CB  . ASP D 1 28  ? 130.849 125.009 108.510 1.00 47.11 ? 28  ASP D CB  1 
ATOM   9832  C CG  . ASP D 1 28  ? 131.252 126.383 108.947 1.00 47.11 ? 28  ASP D CG  1 
ATOM   9833  O OD1 . ASP D 1 28  ? 130.362 127.156 109.352 1.00 47.11 ? 28  ASP D OD1 1 
ATOM   9834  O OD2 . ASP D 1 28  ? 132.458 126.693 108.888 1.00 47.11 ? 28  ASP D OD2 1 
ATOM   9835  N N   . PHE D 1 29  ? 130.281 122.085 108.715 1.00 44.44 ? 29  PHE D N   1 
ATOM   9836  C CA  . PHE D 1 29  ? 129.909 120.774 108.204 1.00 44.44 ? 29  PHE D CA  1 
ATOM   9837  C C   . PHE D 1 29  ? 128.812 120.146 109.044 1.00 44.44 ? 29  PHE D C   1 
ATOM   9838  O O   . PHE D 1 29  ? 127.841 119.603 108.510 1.00 44.44 ? 29  PHE D O   1 
ATOM   9839  C CB  . PHE D 1 29  ? 131.143 119.877 108.177 1.00 44.44 ? 29  PHE D CB  1 
ATOM   9840  C CG  . PHE D 1 29  ? 130.970 118.628 107.373 1.00 44.44 ? 29  PHE D CG  1 
ATOM   9841  C CD1 . PHE D 1 29  ? 130.211 118.627 106.221 1.00 44.44 ? 29  PHE D CD1 1 
ATOM   9842  C CD2 . PHE D 1 29  ? 131.582 117.455 107.761 1.00 44.44 ? 29  PHE D CD2 1 
ATOM   9843  C CE1 . PHE D 1 29  ? 130.061 117.481 105.482 1.00 44.44 ? 29  PHE D CE1 1 
ATOM   9844  C CE2 . PHE D 1 29  ? 131.432 116.308 107.025 1.00 44.44 ? 29  PHE D CE2 1 
ATOM   9845  C CZ  . PHE D 1 29  ? 130.671 116.322 105.885 1.00 44.44 ? 29  PHE D CZ  1 
ATOM   9846  N N   . LEU D 1 30  ? 128.939 120.227 110.364 1.00 40.06 ? 30  LEU D N   1 
ATOM   9847  C CA  . LEU D 1 30  ? 127.985 119.567 111.235 1.00 40.06 ? 30  LEU D CA  1 
ATOM   9848  C C   . LEU D 1 30  ? 126.620 120.226 111.156 1.00 40.06 ? 30  LEU D C   1 
ATOM   9849  O O   . LEU D 1 30  ? 125.603 119.535 111.092 1.00 40.06 ? 30  LEU D O   1 
ATOM   9850  C CB  . LEU D 1 30  ? 128.519 119.557 112.660 1.00 40.06 ? 30  LEU D CB  1 
ATOM   9851  C CG  . LEU D 1 30  ? 129.564 118.468 112.892 1.00 40.06 ? 30  LEU D CG  1 
ATOM   9852  C CD1 . LEU D 1 30  ? 130.197 118.602 114.262 1.00 40.06 ? 30  LEU D CD1 1 
ATOM   9853  C CD2 . LEU D 1 30  ? 128.943 117.108 112.714 1.00 40.06 ? 30  LEU D CD2 1 
ATOM   9854  N N   . GLY D 1 31  ? 126.568 121.553 111.142 1.00 43.06 ? 31  GLY D N   1 
ATOM   9855  C CA  . GLY D 1 31  ? 125.300 122.217 110.919 1.00 43.06 ? 31  GLY D CA  1 
ATOM   9856  C C   . GLY D 1 31  ? 124.707 121.861 109.577 1.00 43.06 ? 31  GLY D C   1 
ATOM   9857  O O   . GLY D 1 31  ? 123.487 121.888 109.403 1.00 43.06 ? 31  GLY D O   1 
ATOM   9858  N N   . ARG D 1 32  ? 125.560 121.506 108.617 1.00 43.99 ? 32  ARG D N   1 
ATOM   9859  C CA  . ARG D 1 32  ? 125.057 121.067 107.323 1.00 43.99 ? 32  ARG D CA  1 
ATOM   9860  C C   . ARG D 1 32  ? 124.446 119.673 107.400 1.00 43.99 ? 32  ARG D C   1 
ATOM   9861  O O   . ARG D 1 32  ? 123.375 119.431 106.835 1.00 43.99 ? 32  ARG D O   1 
ATOM   9862  C CB  . ARG D 1 32  ? 126.177 121.110 106.292 1.00 43.99 ? 32  ARG D CB  1 
ATOM   9863  C CG  . ARG D 1 32  ? 126.615 122.508 105.951 1.00 43.99 ? 32  ARG D CG  1 
ATOM   9864  C CD  . ARG D 1 32  ? 126.931 122.627 104.498 1.00 43.99 ? 32  ARG D CD  1 
ATOM   9865  N NE  . ARG D 1 32  ? 128.243 122.080 104.210 1.00 43.99 ? 32  ARG D NE  1 
ATOM   9866  C CZ  . ARG D 1 32  ? 129.344 122.812 104.149 1.00 43.99 ? 32  ARG D CZ  1 
ATOM   9867  N NH1 . ARG D 1 32  ? 129.276 124.116 104.360 1.00 43.99 ? 32  ARG D NH1 1 
ATOM   9868  N NH2 . ARG D 1 32  ? 130.508 122.243 103.881 1.00 43.99 ? 32  ARG D NH2 1 
ATOM   9869  N N   . VAL D 1 33  ? 125.098 118.746 108.101 1.00 40.53 ? 33  VAL D N   1 
ATOM   9870  C CA  . VAL D 1 33  ? 124.686 117.347 108.032 1.00 40.53 ? 33  VAL D CA  1 
ATOM   9871  C C   . VAL D 1 33  ? 123.782 116.940 109.190 1.00 40.53 ? 33  VAL D C   1 
ATOM   9872  O O   . VAL D 1 33  ? 122.938 116.054 109.032 1.00 40.53 ? 33  VAL D O   1 
ATOM   9873  C CB  . VAL D 1 33  ? 125.905 116.409 107.947 1.00 40.53 ? 33  VAL D CB  1 
ATOM   9874  C CG1 . VAL D 1 33  ? 126.844 116.861 106.868 1.00 40.53 ? 33  VAL D CG1 1 
ATOM   9875  C CG2 . VAL D 1 33  ? 126.614 116.332 109.259 1.00 40.53 ? 33  VAL D CG2 1 
ATOM   9876  N N   . LEU D 1 34  ? 123.926 117.574 110.348 1.00 37.32 ? 34  LEU D N   1 
ATOM   9877  C CA  . LEU D 1 34  ? 123.229 117.088 111.530 1.00 37.32 ? 34  LEU D CA  1 
ATOM   9878  C C   . LEU D 1 34  ? 121.738 117.366 111.444 1.00 37.32 ? 34  LEU D C   1 
ATOM   9879  O O   . LEU D 1 34  ? 121.302 118.386 110.913 1.00 37.32 ? 34  LEU D O   1 
ATOM   9880  C CB  . LEU D 1 34  ? 123.784 117.728 112.799 1.00 37.32 ? 34  LEU D CB  1 
ATOM   9881  C CG  . LEU D 1 34  ? 125.165 117.292 113.277 1.00 37.32 ? 34  LEU D CG  1 
ATOM   9882  C CD1 . LEU D 1 34  ? 125.598 118.118 114.461 1.00 37.32 ? 34  LEU D CD1 1 
ATOM   9883  C CD2 . LEU D 1 34  ? 125.169 115.831 113.617 1.00 37.32 ? 34  LEU D CD2 1 
ATOM   9884  N N   . GLN D 1 35  ? 120.957 116.437 111.973 1.00 41.30 ? 35  GLN D N   1 
ATOM   9885  C CA  . GLN D 1 35  ? 119.534 116.632 112.175 1.00 41.30 ? 35  GLN D CA  1 
ATOM   9886  C C   . GLN D 1 35  ? 119.325 117.110 113.599 1.00 41.30 ? 35  GLN D C   1 
ATOM   9887  O O   . GLN D 1 35  ? 119.866 116.521 114.536 1.00 41.30 ? 35  GLN D O   1 
ATOM   9888  C CB  . GLN D 1 35  ? 118.753 115.342 111.935 1.00 41.30 ? 35  GLN D CB  1 
ATOM   9889  C CG  . GLN D 1 35  ? 119.169 114.572 110.707 1.00 41.30 ? 35  GLN D CG  1 
ATOM   9890  C CD  . GLN D 1 35  ? 118.680 115.214 109.441 1.00 41.30 ? 35  GLN D CD  1 
ATOM   9891  O OE1 . GLN D 1 35  ? 119.455 115.473 108.524 1.00 41.30 ? 35  GLN D OE1 1 
ATOM   9892  N NE2 . GLN D 1 35  ? 117.386 115.483 109.382 1.00 41.30 ? 35  GLN D NE2 1 
ATOM   9893  N N   . PHE D 1 36  ? 118.551 118.172 113.758 1.00 38.12 ? 36  PHE D N   1 
ATOM   9894  C CA  . PHE D 1 36  ? 118.305 118.772 115.057 1.00 38.12 ? 36  PHE D CA  1 
ATOM   9895  C C   . PHE D 1 36  ? 116.902 118.429 115.520 1.00 38.12 ? 36  PHE D C   1 
ATOM   9896  O O   . PHE D 1 36  ? 115.947 118.527 114.748 1.00 38.12 ? 36  PHE D O   1 
ATOM   9897  C CB  . PHE D 1 36  ? 118.485 120.283 114.993 1.00 38.12 ? 36  PHE D CB  1 
ATOM   9898  C CG  . PHE D 1 36  ? 119.899 120.704 114.790 1.00 38.12 ? 36  PHE D CG  1 
ATOM   9899  C CD1 . PHE D 1 36  ? 120.408 120.862 113.528 1.00 38.12 ? 36  PHE D CD1 1 
ATOM   9900  C CD2 . PHE D 1 36  ? 120.723 120.932 115.866 1.00 38.12 ? 36  PHE D CD2 1 
ATOM   9901  C CE1 . PHE D 1 36  ? 121.708 121.242 113.346 1.00 38.12 ? 36  PHE D CE1 1 
ATOM   9902  C CE2 . PHE D 1 36  ? 122.018 121.314 115.686 1.00 38.12 ? 36  PHE D CE2 1 
ATOM   9903  C CZ  . PHE D 1 36  ? 122.511 121.471 114.425 1.00 38.12 ? 36  PHE D CZ  1 
ATOM   9904  N N   . GLN D 1 37  ? 116.781 118.022 116.783 1.00 42.27 ? 37  GLN D N   1 
ATOM   9905  C CA  . GLN D 1 37  ? 115.470 117.658 117.304 1.00 42.27 ? 37  GLN D CA  1 
ATOM   9906  C C   . GLN D 1 37  ? 114.534 118.853 117.350 1.00 42.27 ? 37  GLN D C   1 
ATOM   9907  O O   . GLN D 1 37  ? 113.318 118.695 117.214 1.00 42.27 ? 37  GLN D O   1 
ATOM   9908  C CB  . GLN D 1 37  ? 115.594 117.068 118.701 1.00 42.27 ? 37  GLN D CB  1 
ATOM   9909  C CG  . GLN D 1 37  ? 116.677 116.054 118.876 1.00 42.27 ? 37  GLN D CG  1 
ATOM   9910  C CD  . GLN D 1 37  ? 116.647 115.454 120.261 1.00 42.27 ? 37  GLN D CD  1 
ATOM   9911  O OE1 . GLN D 1 37  ? 115.583 115.311 120.858 1.00 42.27 ? 37  GLN D OE1 1 
ATOM   9912  N NE2 . GLN D 1 37  ? 117.816 115.127 120.794 1.00 42.27 ? 37  GLN D NE2 1 
ATOM   9913  N N   . HIS D 1 38  ? 115.075 120.049 117.548 1.00 36.98 ? 38  HIS D N   1 
ATOM   9914  C CA  . HIS D 1 38  ? 114.267 121.237 117.734 1.00 36.98 ? 38  HIS D CA  1 
ATOM   9915  C C   . HIS D 1 38  ? 114.940 122.412 117.048 1.00 36.98 ? 38  HIS D C   1 
ATOM   9916  O O   . HIS D 1 38  ? 116.166 122.469 116.943 1.00 36.98 ? 38  HIS D O   1 
ATOM   9917  C CB  . HIS D 1 38  ? 114.065 121.524 119.218 1.00 36.98 ? 38  HIS D CB  1 
ATOM   9918  C CG  . HIS D 1 38  ? 112.987 122.516 119.503 1.00 36.98 ? 38  HIS D CG  1 
ATOM   9919  N ND1 . HIS D 1 38  ? 113.155 123.869 119.319 1.00 36.98 ? 38  HIS D ND1 1 
ATOM   9920  C CD2 . HIS D 1 38  ? 111.731 122.354 119.974 1.00 36.98 ? 38  HIS D CD2 1 
ATOM   9921  C CE1 . HIS D 1 38  ? 112.047 124.499 119.657 1.00 36.98 ? 38  HIS D CE1 1 
ATOM   9922  N NE2 . HIS D 1 38  ? 111.166 123.602 120.058 1.00 36.98 ? 38  HIS D NE2 1 
ATOM   9923  N N   . GLY D 1 39  ? 114.119 123.349 116.573 1.00 38.72 ? 39  GLY D N   1 
ATOM   9924  C CA  . GLY D 1 39  ? 114.657 124.512 115.891 1.00 38.72 ? 39  GLY D CA  1 
ATOM   9925  C C   . GLY D 1 39  ? 115.505 125.381 116.797 1.00 38.72 ? 39  GLY D C   1 
ATOM   9926  O O   . GLY D 1 39  ? 116.524 125.927 116.372 1.00 38.72 ? 39  GLY D O   1 
ATOM   9927  N N   . ASP D 1 40  ? 115.090 125.527 118.056 1.00 38.90 ? 40  ASP D N   1 
ATOM   9928  C CA  . ASP D 1 40  ? 115.875 126.303 119.006 1.00 38.90 ? 40  ASP D CA  1 
ATOM   9929  C C   . ASP D 1 40  ? 117.256 125.712 119.194 1.00 38.90 ? 40  ASP D C   1 
ATOM   9930  O O   . ASP D 1 40  ? 118.220 126.453 119.386 1.00 38.90 ? 40  ASP D O   1 
ATOM   9931  C CB  . ASP D 1 40  ? 115.159 126.390 120.349 1.00 38.90 ? 40  ASP D CB  1 
ATOM   9932  C CG  . ASP D 1 40  ? 114.271 127.608 120.455 1.00 38.90 ? 40  ASP D CG  1 
ATOM   9933  O OD1 . ASP D 1 40  ? 114.165 128.349 119.461 1.00 38.90 ? 40  ASP D OD1 1 
ATOM   9934  O OD2 . ASP D 1 40  ? 113.671 127.827 121.527 1.00 38.90 ? 40  ASP D OD2 1 
ATOM   9935  N N   . HIS D 1 41  ? 117.380 124.387 119.142 1.00 35.70 ? 41  HIS D N   1 
ATOM   9936  C CA  . HIS D 1 41  ? 118.709 123.797 119.172 1.00 35.70 ? 41  HIS D CA  1 
ATOM   9937  C C   . HIS D 1 41  ? 119.511 124.220 117.954 1.00 35.70 ? 41  HIS D C   1 
ATOM   9938  O O   . HIS D 1 41  ? 120.714 124.447 118.053 1.00 35.70 ? 41  HIS D O   1 
ATOM   9939  C CB  . HIS D 1 41  ? 118.633 122.272 119.246 1.00 35.70 ? 41  HIS D CB  1 
ATOM   9940  C CG  . HIS D 1 41  ? 117.696 121.745 120.288 1.00 35.70 ? 41  HIS D CG  1 
ATOM   9941  N ND1 . HIS D 1 41  ? 117.407 120.405 120.407 1.00 35.70 ? 41  HIS D ND1 1 
ATOM   9942  C CD2 . HIS D 1 41  ? 116.984 122.368 121.253 1.00 35.70 ? 41  HIS D CD2 1 
ATOM   9943  C CE1 . HIS D 1 41  ? 116.552 120.226 121.395 1.00 35.70 ? 41  HIS D CE1 1 
ATOM   9944  N NE2 . HIS D 1 41  ? 116.278 121.402 121.924 1.00 35.70 ? 41  HIS D NE2 1 
ATOM   9945  N N   . LYS D 1 42  ? 118.854 124.378 116.808 1.00 38.92 ? 42  LYS D N   1 
ATOM   9946  C CA  . LYS D 1 42  ? 119.559 124.824 115.612 1.00 38.92 ? 42  LYS D CA  1 
ATOM   9947  C C   . LYS D 1 42  ? 120.037 126.262 115.753 1.00 38.92 ? 42  LYS D C   1 
ATOM   9948  O O   . LYS D 1 42  ? 121.168 126.590 115.381 1.00 38.92 ? 42  LYS D O   1 
ATOM   9949  C CB  . LYS D 1 42  ? 118.651 124.672 114.400 1.00 38.92 ? 42  LYS D CB  1 
ATOM   9950  C CG  . LYS D 1 42  ? 119.237 125.193 113.118 1.00 38.92 ? 42  LYS D CG  1 
ATOM   9951  C CD  . LYS D 1 42  ? 120.527 124.496 112.783 1.00 38.92 ? 42  LYS D CD  1 
ATOM   9952  C CE  . LYS D 1 42  ? 120.920 124.756 111.349 1.00 38.92 ? 42  LYS D CE  1 
ATOM   9953  N NZ  . LYS D 1 42  ? 122.352 125.116 111.238 1.00 38.92 ? 42  LYS D NZ  1 
ATOM   9954  N N   . ARG D 1 43  ? 119.192 127.134 116.296 1.00 39.35 ? 43  ARG D N   1 
ATOM   9955  C CA  . ARG D 1 43  ? 119.579 128.528 116.456 1.00 39.35 ? 43  ARG D CA  1 
ATOM   9956  C C   . ARG D 1 43  ? 120.671 128.682 117.505 1.00 39.35 ? 43  ARG D C   1 
ATOM   9957  O O   . ARG D 1 43  ? 121.639 129.428 117.302 1.00 39.35 ? 43  ARG D O   1 
ATOM   9958  C CB  . ARG D 1 43  ? 118.351 129.349 116.806 1.00 39.35 ? 43  ARG D CB  1 
ATOM   9959  C CG  . ARG D 1 43  ? 117.152 128.937 115.993 1.00 39.35 ? 43  ARG D CG  1 
ATOM   9960  C CD  . ARG D 1 43  ? 115.915 129.709 116.360 1.00 39.35 ? 43  ARG D CD  1 
ATOM   9961  N NE  . ARG D 1 43  ? 116.164 131.143 116.349 1.00 39.35 ? 43  ARG D NE  1 
ATOM   9962  C CZ  . ARG D 1 43  ? 116.256 131.881 115.247 1.00 39.35 ? 43  ARG D CZ  1 
ATOM   9963  N NH1 . ARG D 1 43  ? 116.486 133.183 115.340 1.00 39.35 ? 43  ARG D NH1 1 
ATOM   9964  N NH2 . ARG D 1 43  ? 116.115 131.323 114.053 1.00 39.35 ? 43  ARG D NH2 1 
ATOM   9965  N N   . TRP D 1 44  ? 120.541 127.978 118.628 1.00 36.32 ? 44  TRP D N   1 
ATOM   9966  C CA  . TRP D 1 44  ? 121.624 127.938 119.596 1.00 36.32 ? 44  TRP D CA  1 
ATOM   9967  C C   . TRP D 1 44  ? 122.888 127.384 118.976 1.00 36.32 ? 44  TRP D C   1 
ATOM   9968  O O   . TRP D 1 44  ? 123.983 127.801 119.344 1.00 36.32 ? 44  TRP D O   1 
ATOM   9969  C CB  . TRP D 1 44  ? 121.237 127.090 120.801 1.00 36.32 ? 44  TRP D CB  1 
ATOM   9970  C CG  . TRP D 1 44  ? 120.342 127.745 121.792 1.00 36.32 ? 44  TRP D CG  1 
ATOM   9971  C CD1 . TRP D 1 44  ? 119.132 127.305 122.198 1.00 36.32 ? 44  TRP D CD1 1 
ATOM   9972  C CD2 . TRP D 1 44  ? 120.598 128.940 122.525 1.00 36.32 ? 44  TRP D CD2 1 
ATOM   9973  N NE1 . TRP D 1 44  ? 118.605 128.151 123.129 1.00 36.32 ? 44  TRP D NE1 1 
ATOM   9974  C CE2 . TRP D 1 44  ? 119.490 129.168 123.346 1.00 36.32 ? 44  TRP D CE2 1 
ATOM   9975  C CE3 . TRP D 1 44  ? 121.658 129.844 122.561 1.00 36.32 ? 44  TRP D CE3 1 
ATOM   9976  C CZ2 . TRP D 1 44  ? 119.406 130.257 124.189 1.00 36.32 ? 44  TRP D CZ2 1 
ATOM   9977  C CZ3 . TRP D 1 44  ? 121.573 130.920 123.399 1.00 36.32 ? 44  TRP D CZ3 1 
ATOM   9978  C CH2 . TRP D 1 44  ? 120.457 131.121 124.200 1.00 36.32 ? 44  TRP D CH2 1 
ATOM   9979  N N   . TRP D 1 45  ? 122.768 126.428 118.057 1.00 36.15 ? 45  TRP D N   1 
ATOM   9980  C CA  . TRP D 1 45  ? 123.950 125.933 117.368 1.00 36.15 ? 45  TRP D CA  1 
ATOM   9981  C C   . TRP D 1 45  ? 124.606 127.053 116.590 1.00 36.15 ? 45  TRP D C   1 
ATOM   9982  O O   . TRP D 1 45  ? 125.795 127.330 116.761 1.00 36.15 ? 45  TRP D O   1 
ATOM   9983  C CB  . TRP D 1 45  ? 123.581 124.779 116.434 1.00 36.15 ? 45  TRP D CB  1 
ATOM   9984  C CG  . TRP D 1 45  ? 124.758 124.237 115.666 1.00 36.15 ? 45  TRP D CG  1 
ATOM   9985  C CD1 . TRP D 1 45  ? 125.141 124.579 114.407 1.00 36.15 ? 45  TRP D CD1 1 
ATOM   9986  C CD2 . TRP D 1 45  ? 125.705 123.267 116.120 1.00 36.15 ? 45  TRP D CD2 1 
ATOM   9987  N NE1 . TRP D 1 45  ? 126.264 123.887 114.049 1.00 36.15 ? 45  TRP D NE1 1 
ATOM   9988  C CE2 . TRP D 1 45  ? 126.629 123.072 115.085 1.00 36.15 ? 45  TRP D CE2 1 
ATOM   9989  C CE3 . TRP D 1 45  ? 125.861 122.545 117.303 1.00 36.15 ? 45  TRP D CE3 1 
ATOM   9990  C CZ2 . TRP D 1 45  ? 127.691 122.188 115.197 1.00 36.15 ? 45  TRP D CZ2 1 
ATOM   9991  C CZ3 . TRP D 1 45  ? 126.915 121.669 117.408 1.00 36.15 ? 45  TRP D CZ3 1 
ATOM   9992  C CH2 . TRP D 1 45  ? 127.816 121.498 116.364 1.00 36.15 ? 45  TRP D CH2 1 
ATOM   9993  N N   . ASP D 1 46  ? 123.820 127.732 115.758 1.00 37.13 ? 46  ASP D N   1 
ATOM   9994  C CA  . ASP D 1 46  ? 124.338 128.821 114.942 1.00 37.13 ? 46  ASP D CA  1 
ATOM   9995  C C   . ASP D 1 46  ? 125.057 129.859 115.782 1.00 37.13 ? 46  ASP D C   1 
ATOM   9996  O O   . ASP D 1 46  ? 126.071 130.417 115.357 1.00 37.13 ? 46  ASP D O   1 
ATOM   9997  C CB  . ASP D 1 46  ? 123.197 129.466 114.170 1.00 37.13 ? 46  ASP D CB  1 
ATOM   9998  C CG  . ASP D 1 46  ? 122.620 128.549 113.136 1.00 37.13 ? 46  ASP D CG  1 
ATOM   9999  O OD1 . ASP D 1 46  ? 123.350 127.658 112.666 1.00 37.13 ? 46  ASP D OD1 1 
ATOM   10000 O OD2 . ASP D 1 46  ? 121.437 128.717 112.788 1.00 37.13 ? 46  ASP D OD2 1 
ATOM   10001 N N   . VAL D 1 47  ? 124.548 130.133 116.980 1.00 37.11 ? 47  VAL D N   1 
ATOM   10002 C CA  . VAL D 1 47  ? 125.176 131.139 117.835 1.00 37.11 ? 47  VAL D CA  1 
ATOM   10003 C C   . VAL D 1 47  ? 126.410 130.577 118.529 1.00 37.11 ? 47  VAL D C   1 
ATOM   10004 O O   . VAL D 1 47  ? 127.526 131.074 118.351 1.00 37.11 ? 47  VAL D O   1 
ATOM   10005 C CB  . VAL D 1 47  ? 124.165 131.681 118.856 1.00 37.11 ? 47  VAL D CB  1 
ATOM   10006 C CG1 . VAL D 1 47  ? 124.789 132.791 119.668 1.00 37.11 ? 47  VAL D CG1 1 
ATOM   10007 C CG2 . VAL D 1 47  ? 122.942 132.177 118.149 1.00 37.11 ? 47  VAL D CG2 1 
ATOM   10008 N N   . LEU D 1 48  ? 126.229 129.538 119.336 1.00 36.66 ? 48  LEU D N   1 
ATOM   10009 C CA  . LEU D 1 48  ? 127.283 129.059 120.216 1.00 36.66 ? 48  LEU D CA  1 
ATOM   10010 C C   . LEU D 1 48  ? 128.364 128.316 119.457 1.00 36.66 ? 48  LEU D C   1 
ATOM   10011 O O   . LEU D 1 48  ? 129.551 128.589 119.643 1.00 36.66 ? 48  LEU D O   1 
ATOM   10012 C CB  . LEU D 1 48  ? 126.691 128.145 121.285 1.00 36.66 ? 48  LEU D CB  1 
ATOM   10013 C CG  . LEU D 1 48  ? 125.573 128.709 122.149 1.00 36.66 ? 48  LEU D CG  1 
ATOM   10014 C CD1 . LEU D 1 48  ? 125.108 127.661 123.113 1.00 36.66 ? 48  LEU D CD1 1 
ATOM   10015 C CD2 . LEU D 1 48  ? 126.066 129.915 122.889 1.00 36.66 ? 48  LEU D CD2 1 
ATOM   10016 N N   . ALA D 1 49  ? 127.973 127.349 118.631 1.00 38.56 ? 49  ALA D N   1 
ATOM   10017 C CA  . ALA D 1 49  ? 128.934 126.457 117.994 1.00 38.56 ? 49  ALA D CA  1 
ATOM   10018 C C   . ALA D 1 49  ? 130.095 127.178 117.335 1.00 38.56 ? 49  ALA D C   1 
ATOM   10019 O O   . ALA D 1 49  ? 131.220 126.666 117.420 1.00 38.56 ? 49  ALA D O   1 
ATOM   10020 C CB  . ALA D 1 49  ? 128.205 125.569 116.981 1.00 38.56 ? 49  ALA D CB  1 
ATOM   10021 N N   . PRO D 1 50  ? 129.922 128.326 116.680 1.00 38.29 ? 50  PRO D N   1 
ATOM   10022 C CA  . PRO D 1 50  ? 131.108 129.069 116.246 1.00 38.29 ? 50  PRO D CA  1 
ATOM   10023 C C   . PRO D 1 50  ? 132.003 129.473 117.397 1.00 38.29 ? 50  PRO D C   1 
ATOM   10024 O O   . PRO D 1 50  ? 133.208 129.237 117.342 1.00 38.29 ? 50  PRO D O   1 
ATOM   10025 C CB  . PRO D 1 50  ? 130.508 130.275 115.530 1.00 38.29 ? 50  PRO D CB  1 
ATOM   10026 C CG  . PRO D 1 50  ? 129.225 129.793 115.041 1.00 38.29 ? 50  PRO D CG  1 
ATOM   10027 C CD  . PRO D 1 50  ? 128.701 128.891 116.092 1.00 38.29 ? 50  PRO D CD  1 
ATOM   10028 N N   . VAL D 1 51  ? 131.446 130.064 118.452 1.00 41.61 ? 51  VAL D N   1 
ATOM   10029 C CA  . VAL D 1 51  ? 132.267 130.519 119.573 1.00 41.61 ? 51  VAL D CA  1 
ATOM   10030 C C   . VAL D 1 51  ? 132.970 129.341 120.235 1.00 41.61 ? 51  VAL D C   1 
ATOM   10031 O O   . VAL D 1 51  ? 134.179 129.372 120.493 1.00 41.61 ? 51  VAL D O   1 
ATOM   10032 C CB  . VAL D 1 51  ? 131.400 131.292 120.582 1.00 41.61 ? 51  VAL D CB  1 
ATOM   10033 C CG1 . VAL D 1 51  ? 132.189 131.583 121.840 1.00 41.61 ? 51  VAL D CG1 1 
ATOM   10034 C CG2 . VAL D 1 51  ? 130.870 132.568 119.963 1.00 41.61 ? 51  VAL D CG2 1 
ATOM   10035 N N   . PHE D 1 52  ? 132.214 128.287 120.525 1.00 42.96 ? 52  PHE D N   1 
ATOM   10036 C CA  . PHE D 1 52  ? 132.786 127.102 121.145 1.00 42.96 ? 52  PHE D CA  1 
ATOM   10037 C C   . PHE D 1 52  ? 133.863 126.490 120.263 1.00 42.96 ? 52  PHE D C   1 
ATOM   10038 O O   . PHE D 1 52  ? 134.974 126.209 120.723 1.00 42.96 ? 52  PHE D O   1 
ATOM   10039 C CB  . PHE D 1 52  ? 131.677 126.094 121.423 1.00 42.96 ? 52  PHE D CB  1 
ATOM   10040 C CG  . PHE D 1 52  ? 130.872 126.409 122.640 1.00 42.96 ? 52  PHE D CG  1 
ATOM   10041 C CD1 . PHE D 1 52  ? 130.942 127.653 123.231 1.00 42.96 ? 52  PHE D CD1 1 
ATOM   10042 C CD2 . PHE D 1 52  ? 130.046 125.463 123.204 1.00 42.96 ? 52  PHE D CD2 1 
ATOM   10043 C CE1 . PHE D 1 52  ? 130.205 127.944 124.352 1.00 42.96 ? 52  PHE D CE1 1 
ATOM   10044 C CE2 . PHE D 1 52  ? 129.308 125.756 124.326 1.00 42.96 ? 52  PHE D CE2 1 
ATOM   10045 C CZ  . PHE D 1 52  ? 129.387 126.997 124.896 1.00 42.96 ? 52  PHE D CZ  1 
ATOM   10046 N N   . GLY D 1 53  ? 133.549 126.283 118.985 1.00 43.88 ? 53  GLY D N   1 
ATOM   10047 C CA  . GLY D 1 53  ? 134.502 125.692 118.071 1.00 43.88 ? 53  GLY D CA  1 
ATOM   10048 C C   . GLY D 1 53  ? 135.740 126.534 117.868 1.00 43.88 ? 53  GLY D C   1 
ATOM   10049 O O   . GLY D 1 53  ? 136.823 125.997 117.654 1.00 43.88 ? 53  GLY D O   1 
ATOM   10050 N N   . ILE D 1 54  ? 135.610 127.856 117.958 1.00 45.56 ? 54  ILE D N   1 
ATOM   10051 C CA  . ILE D 1 54  ? 136.774 128.706 117.755 1.00 45.56 ? 54  ILE D CA  1 
ATOM   10052 C C   . ILE D 1 54  ? 137.622 128.765 119.014 1.00 45.56 ? 54  ILE D C   1 
ATOM   10053 O O   . ILE D 1 54  ? 138.847 128.884 118.938 1.00 45.56 ? 54  ILE D O   1 
ATOM   10054 C CB  . ILE D 1 54  ? 136.336 130.102 117.291 1.00 45.56 ? 54  ILE D CB  1 
ATOM   10055 C CG1 . ILE D 1 54  ? 135.863 130.044 115.839 1.00 45.56 ? 54  ILE D CG1 1 
ATOM   10056 C CG2 . ILE D 1 54  ? 137.469 131.095 117.422 1.00 45.56 ? 54  ILE D CG2 1 
ATOM   10057 C CD1 . ILE D 1 54  ? 134.861 131.111 115.474 1.00 45.56 ? 54  ILE D CD1 1 
ATOM   10058 N N   . SER D 1 55  ? 137.005 128.657 120.185 1.00 47.89 ? 55  SER D N   1 
ATOM   10059 C CA  . SER D 1 55  ? 137.795 128.500 121.398 1.00 47.89 ? 55  SER D CA  1 
ATOM   10060 C C   . SER D 1 55  ? 138.540 127.174 121.385 1.00 47.89 ? 55  SER D C   1 
ATOM   10061 O O   . SER D 1 55  ? 139.695 127.090 121.817 1.00 47.89 ? 55  SER D O   1 
ATOM   10062 C CB  . SER D 1 55  ? 136.887 128.596 122.617 1.00 47.89 ? 55  SER D CB  1 
ATOM   10063 O OG  . SER D 1 55  ? 136.249 129.857 122.667 1.00 47.89 ? 55  SER D OG  1 
ATOM   10064 N N   . MET D 1 56  ? 137.884 126.125 120.893 1.00 48.14 ? 56  MET D N   1 
ATOM   10065 C CA  . MET D 1 56  ? 138.524 124.824 120.795 1.00 48.14 ? 56  MET D CA  1 
ATOM   10066 C C   . MET D 1 56  ? 139.664 124.834 119.782 1.00 48.14 ? 56  MET D C   1 
ATOM   10067 O O   . MET D 1 56  ? 140.762 124.352 120.074 1.00 48.14 ? 56  MET D O   1 
ATOM   10068 C CB  . MET D 1 56  ? 137.482 123.775 120.429 1.00 48.14 ? 56  MET D CB  1 
ATOM   10069 C CG  . MET D 1 56  ? 136.369 123.633 121.442 1.00 48.14 ? 56  MET D CG  1 
ATOM   10070 S SD  . MET D 1 56  ? 135.253 122.282 121.028 1.00 48.14 ? 56  MET D SD  1 
ATOM   10071 C CE  . MET D 1 56  ? 134.007 122.454 122.287 1.00 48.14 ? 56  MET D CE  1 
ATOM   10072 N N   . ALA D 1 57  ? 139.431 125.388 118.598 1.00 49.63 ? 57  ALA D N   1 
ATOM   10073 C CA  . ALA D 1 57  ? 140.395 125.375 117.513 1.00 49.63 ? 57  ALA D CA  1 
ATOM   10074 C C   . ALA D 1 57  ? 141.360 126.538 117.569 1.00 49.63 ? 57  ALA D C   1 
ATOM   10075 O O   . ALA D 1 57  ? 142.190 126.680 116.669 1.00 49.63 ? 57  ALA D O   1 
ATOM   10076 C CB  . ALA D 1 57  ? 139.667 125.390 116.171 1.00 49.63 ? 57  ALA D CB  1 
ATOM   10077 N N   . SER D 1 58  ? 141.259 127.385 118.581 1.00 52.84 ? 58  SER D N   1 
ATOM   10078 C CA  . SER D 1 58  ? 142.179 128.492 118.755 1.00 52.84 ? 58  SER D CA  1 
ATOM   10079 C C   . SER D 1 58  ? 143.161 128.242 119.886 1.00 52.84 ? 58  SER D C   1 
ATOM   10080 O O   . SER D 1 58  ? 143.951 129.126 120.220 1.00 52.84 ? 58  SER D O   1 
ATOM   10081 C CB  . SER D 1 58  ? 141.392 129.776 118.981 1.00 52.84 ? 58  SER D CB  1 
ATOM   10082 O OG  . SER D 1 58  ? 140.523 129.616 120.078 1.00 52.84 ? 58  SER D OG  1 
ATOM   10083 N N   . ILE D 1 59  ? 143.109 127.058 120.489 1.00 52.43 ? 59  ILE D N   1 
ATOM   10084 C CA  . ILE D 1 59  ? 144.151 126.578 121.389 1.00 52.43 ? 59  ILE D CA  1 
ATOM   10085 C C   . ILE D 1 59  ? 144.704 125.231 120.954 1.00 52.43 ? 59  ILE D C   1 
ATOM   10086 O O   . ILE D 1 59  ? 145.752 124.817 121.452 1.00 52.43 ? 59  ILE D O   1 
ATOM   10087 C CB  . ILE D 1 59  ? 143.631 126.503 122.835 1.00 52.43 ? 59  ILE D CB  1 
ATOM   10088 C CG1 . ILE D 1 59  ? 142.424 125.579 122.910 1.00 52.43 ? 59  ILE D CG1 1 
ATOM   10089 C CG2 . ILE D 1 59  ? 143.258 127.876 123.340 1.00 52.43 ? 59  ILE D CG2 1 
ATOM   10090 C CD1 . ILE D 1 59  ? 141.913 125.383 124.292 1.00 52.43 ? 59  ILE D CD1 1 
ATOM   10091 N N   . GLY D 1 60  ? 144.028 124.534 120.047 1.00 52.10 ? 60  GLY D N   1 
ATOM   10092 C CA  . GLY D 1 60  ? 144.540 123.327 119.447 1.00 52.10 ? 60  GLY D CA  1 
ATOM   10093 C C   . GLY D 1 60  ? 143.749 122.063 119.693 1.00 52.10 ? 60  GLY D C   1 
ATOM   10094 O O   . GLY D 1 60  ? 144.305 120.974 119.513 1.00 52.10 ? 60  GLY D O   1 
ATOM   10095 N N   . TYR D 1 61  ? 142.485 122.155 120.100 1.00 46.22 ? 61  TYR D N   1 
ATOM   10096 C CA  . TYR D 1 61  ? 141.689 120.943 120.262 1.00 46.22 ? 61  TYR D CA  1 
ATOM   10097 C C   . TYR D 1 61  ? 141.653 120.167 118.954 1.00 46.22 ? 61  TYR D C   1 
ATOM   10098 O O   . TYR D 1 61  ? 141.142 120.661 117.946 1.00 46.22 ? 61  TYR D O   1 
ATOM   10099 C CB  . TYR D 1 61  ? 140.270 121.286 120.712 1.00 46.22 ? 61  TYR D CB  1 
ATOM   10100 C CG  . TYR D 1 61  ? 140.111 121.488 122.202 1.00 46.22 ? 61  TYR D CG  1 
ATOM   10101 C CD1 . TYR D 1 61  ? 141.174 121.906 122.982 1.00 46.22 ? 61  TYR D CD1 1 
ATOM   10102 C CD2 . TYR D 1 61  ? 138.887 121.279 122.826 1.00 46.22 ? 61  TYR D CD2 1 
ATOM   10103 C CE1 . TYR D 1 61  ? 141.030 122.096 124.334 1.00 46.22 ? 61  TYR D CE1 1 
ATOM   10104 C CE2 . TYR D 1 61  ? 138.735 121.477 124.178 1.00 46.22 ? 61  TYR D CE2 1 
ATOM   10105 C CZ  . TYR D 1 61  ? 139.812 121.885 124.925 1.00 46.22 ? 61  TYR D CZ  1 
ATOM   10106 O OH  . TYR D 1 61  ? 139.681 122.083 126.276 1.00 46.22 ? 61  TYR D OH  1 
ATOM   10107 N N   . LYS D 1 62  ? 142.214 118.957 118.970 1.00 46.31 ? 62  LYS D N   1 
ATOM   10108 C CA  . LYS D 1 62  ? 142.312 118.144 117.764 1.00 46.31 ? 62  LYS D CA  1 
ATOM   10109 C C   . LYS D 1 62  ? 140.952 117.979 117.102 1.00 46.31 ? 62  LYS D C   1 
ATOM   10110 O O   . LYS D 1 62  ? 139.928 117.848 117.771 1.00 46.31 ? 62  LYS D O   1 
ATOM   10111 C CB  . LYS D 1 62  ? 142.906 116.779 118.098 1.00 46.31 ? 62  LYS D CB  1 
ATOM   10112 C CG  . LYS D 1 62  ? 144.288 116.854 118.713 1.00 46.31 ? 62  LYS D CG  1 
ATOM   10113 C CD  . LYS D 1 62  ? 144.804 115.475 119.087 1.00 46.31 ? 62  LYS D CD  1 
ATOM   10114 C CE  . LYS D 1 62  ? 146.197 115.548 119.693 1.00 46.31 ? 62  LYS D CE  1 
ATOM   10115 N NZ  . LYS D 1 62  ? 146.240 116.343 120.951 1.00 46.31 ? 62  LYS D NZ  1 
ATOM   10116 N N   . LEU D 1 63  ? 140.957 117.966 115.772 1.00 46.23 ? 63  LEU D N   1 
ATOM   10117 C CA  . LEU D 1 63  ? 139.721 118.133 115.019 1.00 46.23 ? 63  LEU D CA  1 
ATOM   10118 C C   . LEU D 1 63  ? 138.683 117.075 115.359 1.00 46.23 ? 63  LEU D C   1 
ATOM   10119 O O   . LEU D 1 63  ? 137.484 117.375 115.386 1.00 46.23 ? 63  LEU D O   1 
ATOM   10120 C CB  . LEU D 1 63  ? 140.022 118.117 113.527 1.00 46.23 ? 63  LEU D CB  1 
ATOM   10121 C CG  . LEU D 1 63  ? 139.008 118.875 112.681 1.00 46.23 ? 63  LEU D CG  1 
ATOM   10122 C CD1 . LEU D 1 63  ? 139.119 120.329 113.017 1.00 46.23 ? 63  LEU D CD1 1 
ATOM   10123 C CD2 . LEU D 1 63  ? 139.274 118.669 111.216 1.00 46.23 ? 63  LEU D CD2 1 
ATOM   10124 N N   . ASP D 1 64  ? 139.108 115.836 115.617 1.00 46.28 ? 64  ASP D N   1 
ATOM   10125 C CA  . ASP D 1 64  ? 138.144 114.809 116.001 1.00 46.28 ? 64  ASP D CA  1 
ATOM   10126 C C   . ASP D 1 64  ? 137.652 115.033 117.421 1.00 46.28 ? 64  ASP D C   1 
ATOM   10127 O O   . ASP D 1 64  ? 136.507 114.708 117.749 1.00 46.28 ? 64  ASP D O   1 
ATOM   10128 C CB  . ASP D 1 64  ? 138.756 113.424 115.879 1.00 46.28 ? 64  ASP D CB  1 
ATOM   10129 C CG  . ASP D 1 64  ? 139.830 113.182 116.902 1.00 46.28 ? 64  ASP D CG  1 
ATOM   10130 O OD1 . ASP D 1 64  ? 140.913 113.781 116.774 1.00 46.28 ? 64  ASP D OD1 1 
ATOM   10131 O OD2 . ASP D 1 64  ? 139.583 112.410 117.848 1.00 46.28 ? 64  ASP D OD2 1 
ATOM   10132 N N   . VAL D 1 65  ? 138.504 115.601 118.278 1.00 43.78 ? 65  VAL D N   1 
ATOM   10133 C CA  . VAL D 1 65  ? 138.060 115.996 119.607 1.00 43.78 ? 65  VAL D CA  1 
ATOM   10134 C C   . VAL D 1 65  ? 137.081 117.153 119.503 1.00 43.78 ? 65  VAL D C   1 
ATOM   10135 O O   . VAL D 1 65  ? 136.112 117.238 120.264 1.00 43.78 ? 65  VAL D O   1 
ATOM   10136 C CB  . VAL D 1 65  ? 139.271 116.341 120.489 1.00 43.78 ? 65  VAL D CB  1 
ATOM   10137 C CG1 . VAL D 1 65  ? 138.827 116.930 121.797 1.00 43.78 ? 65  VAL D CG1 1 
ATOM   10138 C CG2 . VAL D 1 65  ? 140.115 115.109 120.730 1.00 43.78 ? 65  VAL D CG2 1 
ATOM   10139 N N   . GLN D 1 66  ? 137.314 118.059 118.556 1.00 41.39 ? 66  GLN D N   1 
ATOM   10140 C CA  . GLN D 1 66  ? 136.328 119.091 118.274 1.00 41.39 ? 66  GLN D CA  1 
ATOM   10141 C C   . GLN D 1 66  ? 135.004 118.465 117.882 1.00 41.39 ? 66  GLN D C   1 
ATOM   10142 O O   . GLN D 1 66  ? 133.948 118.860 118.375 1.00 41.39 ? 66  GLN D O   1 
ATOM   10143 C CB  . GLN D 1 66  ? 136.821 120.007 117.162 1.00 41.39 ? 66  GLN D CB  1 
ATOM   10144 C CG  . GLN D 1 66  ? 137.967 120.894 117.523 1.00 41.39 ? 66  GLN D CG  1 
ATOM   10145 C CD  . GLN D 1 66  ? 138.336 121.804 116.385 1.00 41.39 ? 66  GLN D CD  1 
ATOM   10146 O OE1 . GLN D 1 66  ? 137.501 122.147 115.562 1.00 41.39 ? 66  GLN D OE1 1 
ATOM   10147 N NE2 . GLN D 1 66  ? 139.590 122.189 116.321 1.00 41.39 ? 66  GLN D NE2 1 
ATOM   10148 N N   . TYR D 1 67  ? 135.042 117.497 116.969 1.00 41.60 ? 67  TYR D N   1 
ATOM   10149 C CA  . TYR D 1 67  ? 133.819 116.796 116.601 1.00 41.60 ? 67  TYR D CA  1 
ATOM   10150 C C   . TYR D 1 67  ? 133.143 116.188 117.819 1.00 41.60 ? 67  TYR D C   1 
ATOM   10151 O O   . TYR D 1 67  ? 131.926 116.306 117.981 1.00 41.60 ? 67  TYR D O   1 
ATOM   10152 C CB  . TYR D 1 67  ? 134.119 115.718 115.569 1.00 41.60 ? 67  TYR D CB  1 
ATOM   10153 C CG  . TYR D 1 67  ? 133.967 116.179 114.146 1.00 41.60 ? 67  TYR D CG  1 
ATOM   10154 C CD1 . TYR D 1 67  ? 132.737 116.117 113.510 1.00 41.60 ? 67  TYR D CD1 1 
ATOM   10155 C CD2 . TYR D 1 67  ? 135.049 116.669 113.434 1.00 41.60 ? 67  TYR D CD2 1 
ATOM   10156 C CE1 . TYR D 1 67  ? 132.591 116.534 112.209 1.00 41.60 ? 67  TYR D CE1 1 
ATOM   10157 C CE2 . TYR D 1 67  ? 134.911 117.086 112.135 1.00 41.60 ? 67  TYR D CE2 1 
ATOM   10158 C CZ  . TYR D 1 67  ? 133.683 117.016 111.527 1.00 41.60 ? 67  TYR D CZ  1 
ATOM   10159 O OH  . TYR D 1 67  ? 133.544 117.438 110.230 1.00 41.60 ? 67  TYR D OH  1 
ATOM   10160 N N   . ARG D 1 68  ? 133.920 115.548 118.693 1.00 42.76 ? 68  ARG D N   1 
ATOM   10161 C CA  . ARG D 1 68  ? 133.343 114.882 119.856 1.00 42.76 ? 68  ARG D CA  1 
ATOM   10162 C C   . ARG D 1 68  ? 132.671 115.878 120.786 1.00 42.76 ? 68  ARG D C   1 
ATOM   10163 O O   . ARG D 1 68  ? 131.516 115.693 121.182 1.00 42.76 ? 68  ARG D O   1 
ATOM   10164 C CB  . ARG D 1 68  ? 134.420 114.104 120.602 1.00 42.76 ? 68  ARG D CB  1 
ATOM   10165 C CG  . ARG D 1 68  ? 134.914 112.899 119.848 1.00 42.76 ? 68  ARG D CG  1 
ATOM   10166 C CD  . ARG D 1 68  ? 135.740 112.001 120.729 1.00 42.76 ? 68  ARG D CD  1 
ATOM   10167 N NE  . ARG D 1 68  ? 134.946 111.462 121.820 1.00 42.76 ? 68  ARG D NE  1 
ATOM   10168 C CZ  . ARG D 1 68  ? 135.398 110.577 122.696 1.00 42.76 ? 68  ARG D CZ  1 
ATOM   10169 N NH1 . ARG D 1 68  ? 136.642 110.135 122.605 1.00 42.76 ? 68  ARG D NH1 1 
ATOM   10170 N NH2 . ARG D 1 68  ? 134.607 110.138 123.663 1.00 42.76 ? 68  ARG D NH2 1 
ATOM   10171 N N   . HIS D 1 69  ? 133.384 116.938 121.159 1.00 39.43 ? 69  HIS D N   1 
ATOM   10172 C CA  . HIS D 1 69  ? 132.809 117.910 122.081 1.00 39.43 ? 69  HIS D CA  1 
ATOM   10173 C C   . HIS D 1 69  ? 131.632 118.633 121.453 1.00 39.43 ? 69  HIS D C   1 
ATOM   10174 O O   . HIS D 1 69  ? 130.654 118.933 122.135 1.00 39.43 ? 69  HIS D O   1 
ATOM   10175 C CB  . HIS D 1 69  ? 133.868 118.909 122.531 1.00 39.43 ? 69  HIS D CB  1 
ATOM   10176 C CG  . HIS D 1 69  ? 134.780 118.388 123.597 1.00 39.43 ? 69  HIS D CG  1 
ATOM   10177 N ND1 . HIS D 1 69  ? 134.343 117.583 124.623 1.00 39.43 ? 69  HIS D ND1 1 
ATOM   10178 C CD2 . HIS D 1 69  ? 136.105 118.566 123.799 1.00 39.43 ? 69  HIS D CD2 1 
ATOM   10179 C CE1 . HIS D 1 69  ? 135.360 117.286 125.409 1.00 39.43 ? 69  HIS D CE1 1 
ATOM   10180 N NE2 . HIS D 1 69  ? 136.441 117.869 124.930 1.00 39.43 ? 69  HIS D NE2 1 
ATOM   10181 N N   . LEU D 1 70  ? 131.703 118.917 120.155 1.00 38.36 ? 70  LEU D N   1 
ATOM   10182 C CA  . LEU D 1 70  ? 130.595 119.578 119.489 1.00 38.36 ? 70  LEU D CA  1 
ATOM   10183 C C   . LEU D 1 70  ? 129.394 118.661 119.383 1.00 38.36 ? 70  LEU D C   1 
ATOM   10184 O O   . LEU D 1 70  ? 128.257 119.130 119.420 1.00 38.36 ? 70  LEU D O   1 
ATOM   10185 C CB  . LEU D 1 70  ? 131.035 120.058 118.113 1.00 38.36 ? 70  LEU D CB  1 
ATOM   10186 C CG  . LEU D 1 70  ? 131.965 121.265 118.176 1.00 38.36 ? 70  LEU D CG  1 
ATOM   10187 C CD1 . LEU D 1 70  ? 132.713 121.465 116.878 1.00 38.36 ? 70  LEU D CD1 1 
ATOM   10188 C CD2 . LEU D 1 70  ? 131.174 122.493 118.527 1.00 38.36 ? 70  LEU D CD2 1 
ATOM   10189 N N   . LEU D 1 71  ? 129.616 117.356 119.300 1.00 36.99 ? 71  LEU D N   1 
ATOM   10190 C CA  . LEU D 1 71  ? 128.500 116.425 119.304 1.00 36.99 ? 71  LEU D CA  1 
ATOM   10191 C C   . LEU D 1 71  ? 127.936 116.236 120.699 1.00 36.99 ? 71  LEU D C   1 
ATOM   10192 O O   . LEU D 1 71  ? 126.756 115.917 120.845 1.00 36.99 ? 71  LEU D O   1 
ATOM   10193 C CB  . LEU D 1 71  ? 128.943 115.093 118.714 1.00 36.99 ? 71  LEU D CB  1 
ATOM   10194 C CG  . LEU D 1 71  ? 129.164 115.147 117.207 1.00 36.99 ? 71  LEU D CG  1 
ATOM   10195 C CD1 . LEU D 1 71  ? 129.929 113.938 116.764 1.00 36.99 ? 71  LEU D CD1 1 
ATOM   10196 C CD2 . LEU D 1 71  ? 127.847 115.236 116.479 1.00 36.99 ? 71  LEU D CD2 1 
ATOM   10197 N N   . VAL D 1 72  ? 128.760 116.431 121.726 1.00 37.39 ? 72  VAL D N   1 
ATOM   10198 C CA  . VAL D 1 72  ? 128.259 116.444 123.097 1.00 37.39 ? 72  VAL D CA  1 
ATOM   10199 C C   . VAL D 1 72  ? 127.409 117.684 123.330 1.00 37.39 ? 72  VAL D C   1 
ATOM   10200 O O   . VAL D 1 72  ? 126.297 117.612 123.860 1.00 37.39 ? 72  VAL D O   1 
ATOM   10201 C CB  . VAL D 1 72  ? 129.428 116.368 124.094 1.00 37.39 ? 72  VAL D CB  1 
ATOM   10202 C CG1 . VAL D 1 72  ? 129.007 116.895 125.431 1.00 37.39 ? 72  VAL D CG1 1 
ATOM   10203 C CG2 . VAL D 1 72  ? 129.928 114.949 124.232 1.00 37.39 ? 72  VAL D CG2 1 
ATOM   10204 N N   . LEU D 1 73  ? 127.930 118.841 122.935 1.00 34.75 ? 73  LEU D N   1 
ATOM   10205 C CA  . LEU D 1 73  ? 127.172 120.084 122.969 1.00 34.75 ? 73  LEU D CA  1 
ATOM   10206 C C   . LEU D 1 73  ? 125.886 119.975 122.167 1.00 34.75 ? 73  LEU D C   1 
ATOM   10207 O O   . LEU D 1 73  ? 124.856 120.527 122.554 1.00 34.75 ? 73  LEU D O   1 
ATOM   10208 C CB  . LEU D 1 73  ? 128.058 121.212 122.443 1.00 34.75 ? 73  LEU D CB  1 
ATOM   10209 C CG  . LEU D 1 73  ? 127.484 122.465 121.795 1.00 34.75 ? 73  LEU D CG  1 
ATOM   10210 C CD1 . LEU D 1 73  ? 126.948 123.413 122.825 1.00 34.75 ? 73  LEU D CD1 1 
ATOM   10211 C CD2 . LEU D 1 73  ? 128.552 123.141 120.978 1.00 34.75 ? 73  LEU D CD2 1 
ATOM   10212 N N   . TYR D 1 74  ? 125.930 119.266 121.045 1.00 35.26 ? 74  TYR D N   1 
ATOM   10213 C CA  . TYR D 1 74  ? 124.744 119.042 120.235 1.00 35.26 ? 74  TYR D CA  1 
ATOM   10214 C C   . TYR D 1 74  ? 123.788 118.064 120.897 1.00 35.26 ? 74  TYR D C   1 
ATOM   10215 O O   . TYR D 1 74  ? 122.573 118.154 120.699 1.00 35.26 ? 74  TYR D O   1 
ATOM   10216 C CB  . TYR D 1 74  ? 125.176 118.537 118.862 1.00 35.26 ? 74  TYR D CB  1 
ATOM   10217 C CG  . TYR D 1 74  ? 124.204 117.620 118.162 1.00 35.26 ? 74  TYR D CG  1 
ATOM   10218 C CD1 . TYR D 1 74  ? 123.079 118.119 117.538 1.00 35.26 ? 74  TYR D CD1 1 
ATOM   10219 C CD2 . TYR D 1 74  ? 124.433 116.258 118.094 1.00 35.26 ? 74  TYR D CD2 1 
ATOM   10220 C CE1 . TYR D 1 74  ? 122.202 117.293 116.887 1.00 35.26 ? 74  TYR D CE1 1 
ATOM   10221 C CE2 . TYR D 1 74  ? 123.557 115.427 117.445 1.00 35.26 ? 74  TYR D CE2 1 
ATOM   10222 C CZ  . TYR D 1 74  ? 122.444 115.953 116.846 1.00 35.26 ? 74  TYR D CZ  1 
ATOM   10223 O OH  . TYR D 1 74  ? 121.562 115.137 116.192 1.00 35.26 ? 74  TYR D OH  1 
ATOM   10224 N N   . ASP D 1 75  ? 124.314 117.145 121.698 1.00 39.76 ? 75  ASP D N   1 
ATOM   10225 C CA  . ASP D 1 75  ? 123.549 116.043 122.257 1.00 39.76 ? 75  ASP D CA  1 
ATOM   10226 C C   . ASP D 1 75  ? 123.145 116.256 123.704 1.00 39.76 ? 75  ASP D C   1 
ATOM   10227 O O   . ASP D 1 75  ? 122.021 115.921 124.082 1.00 39.76 ? 75  ASP D O   1 
ATOM   10228 C CB  . ASP D 1 75  ? 124.360 114.757 122.155 1.00 39.76 ? 75  ASP D CB  1 
ATOM   10229 C CG  . ASP D 1 75  ? 123.569 113.544 122.558 1.00 39.76 ? 75  ASP D CG  1 
ATOM   10230 O OD1 . ASP D 1 75  ? 122.436 113.384 122.062 1.00 39.76 ? 75  ASP D OD1 1 
ATOM   10231 O OD2 . ASP D 1 75  ? 124.079 112.751 123.373 1.00 39.76 ? 75  ASP D OD2 1 
ATOM   10232 N N   . ALA D 1 76  ? 124.031 116.806 124.527 1.00 37.09 ? 76  ALA D N   1 
ATOM   10233 C CA  . ALA D 1 76  ? 123.801 116.862 125.962 1.00 37.09 ? 76  ALA D CA  1 
ATOM   10234 C C   . ALA D 1 76  ? 123.364 118.235 126.456 1.00 37.09 ? 76  ALA D C   1 
ATOM   10235 O O   . ALA D 1 76  ? 122.380 118.333 127.190 1.00 37.09 ? 76  ALA D O   1 
ATOM   10236 C CB  . ALA D 1 76  ? 125.063 116.417 126.705 1.00 37.09 ? 76  ALA D CB  1 
ATOM   10237 N N   . VAL D 1 77  ? 124.061 119.302 126.081 1.00 34.74 ? 77  VAL D N   1 
ATOM   10238 C CA  . VAL D 1 77  ? 123.883 120.581 126.745 1.00 34.74 ? 77  VAL D CA  1 
ATOM   10239 C C   . VAL D 1 77  ? 122.886 121.475 126.018 1.00 34.74 ? 77  VAL D C   1 
ATOM   10240 O O   . VAL D 1 77  ? 122.128 122.198 126.660 1.00 34.74 ? 77  VAL D O   1 
ATOM   10241 C CB  . VAL D 1 77  ? 125.241 121.289 126.938 1.00 34.74 ? 77  VAL D CB  1 
ATOM   10242 C CG1 . VAL D 1 77  ? 126.301 120.291 127.335 1.00 34.74 ? 77  VAL D CG1 1 
ATOM   10243 C CG2 . VAL D 1 77  ? 125.645 122.041 125.728 1.00 34.74 ? 77  VAL D CG2 1 
ATOM   10244 N N   . ILE D 1 78  ? 122.847 121.447 124.691 1.00 32.62 ? 78  ILE D N   1 
ATOM   10245 C CA  . ILE D 1 78  ? 121.954 122.343 123.962 1.00 32.62 ? 78  ILE D CA  1 
ATOM   10246 C C   . ILE D 1 78  ? 120.506 121.916 124.161 1.00 32.62 ? 78  ILE D C   1 
ATOM   10247 O O   . ILE D 1 78  ? 119.645 122.784 124.346 1.00 32.62 ? 78  ILE D O   1 
ATOM   10248 C CB  . ILE D 1 78  ? 122.307 122.425 122.471 1.00 32.62 ? 78  ILE D CB  1 
ATOM   10249 C CG1 . ILE D 1 78  ? 123.408 123.449 122.235 1.00 32.62 ? 78  ILE D CG1 1 
ATOM   10250 C CG2 . ILE D 1 78  ? 121.121 122.858 121.687 1.00 32.62 ? 78  ILE D CG2 1 
ATOM   10251 C CD1 . ILE D 1 78  ? 123.817 123.568 120.807 1.00 32.62 ? 78  ILE D CD1 1 
ATOM   10252 N N   . PRO D 1 79  ? 120.169 120.626 124.145 1.00 32.36 ? 79  PRO D N   1 
ATOM   10253 C CA  . PRO D 1 79  ? 118.789 120.253 124.476 1.00 32.36 ? 79  PRO D CA  1 
ATOM   10254 C C   . PRO D 1 79  ? 118.413 120.587 125.906 1.00 32.36 ? 79  PRO D C   1 
ATOM   10255 O O   . PRO D 1 79  ? 117.238 120.511 126.269 1.00 32.36 ? 79  PRO D O   1 
ATOM   10256 C CB  . PRO D 1 79  ? 118.769 118.746 124.228 1.00 32.36 ? 79  PRO D CB  1 
ATOM   10257 C CG  . PRO D 1 79  ? 119.834 118.526 123.262 1.00 32.36 ? 79  PRO D CG  1 
ATOM   10258 C CD  . PRO D 1 79  ? 120.907 119.474 123.607 1.00 32.36 ? 79  PRO D CD  1 
ATOM   10259 N N   . ASN D 1 80  ? 119.394 120.969 126.720 1.00 37.18 ? 80  ASN D N   1 
ATOM   10260 C CA  . ASN D 1 80  ? 119.191 121.336 128.115 1.00 37.18 ? 80  ASN D CA  1 
ATOM   10261 C C   . ASN D 1 80  ? 119.603 122.779 128.363 1.00 37.18 ? 80  ASN D C   1 
ATOM   10262 O O   . ASN D 1 80  ? 120.208 123.091 129.386 1.00 37.18 ? 80  ASN D O   1 
ATOM   10263 C CB  . ASN D 1 80  ? 119.965 120.400 129.040 1.00 37.18 ? 80  ASN D CB  1 
ATOM   10264 C CG  . ASN D 1 80  ? 119.518 118.966 128.916 1.00 37.18 ? 80  ASN D CG  1 
ATOM   10265 O OD1 . ASN D 1 80  ? 118.396 118.624 129.278 1.00 37.18 ? 80  ASN D OD1 1 
ATOM   10266 N ND2 . ASN D 1 80  ? 120.393 118.115 128.401 1.00 37.18 ? 80  ASN D ND2 1 
ATOM   10267 N N   . MET D 1 81  ? 119.297 123.663 127.421 1.00 36.65 ? 81  MET D N   1 
ATOM   10268 C CA  . MET D 1 81  ? 119.651 125.066 127.526 1.00 36.65 ? 81  MET D CA  1 
ATOM   10269 C C   . MET D 1 81  ? 118.438 125.973 127.593 1.00 36.65 ? 81  MET D C   1 
ATOM   10270 O O   . MET D 1 81  ? 118.568 127.132 127.992 1.00 36.65 ? 81  MET D O   1 
ATOM   10271 C CB  . MET D 1 81  ? 120.525 125.475 126.340 1.00 36.65 ? 81  MET D CB  1 
ATOM   10272 C CG  . MET D 1 81  ? 121.289 126.746 126.551 1.00 36.65 ? 81  MET D CG  1 
ATOM   10273 S SD  . MET D 1 81  ? 122.711 126.851 125.483 1.00 36.65 ? 81  MET D SD  1 
ATOM   10274 C CE  . MET D 1 81  ? 123.598 125.401 126.003 1.00 36.65 ? 81  MET D CE  1 
ATOM   10275 N N   . GLY D 1 82  ? 117.266 125.474 127.235 1.00 37.63 ? 82  GLY D N   1 
ATOM   10276 C CA  . GLY D 1 82  ? 116.075 126.276 127.271 1.00 37.63 ? 82  GLY D CA  1 
ATOM   10277 C C   . GLY D 1 82  ? 115.899 127.005 125.967 1.00 37.63 ? 82  GLY D C   1 
ATOM   10278 O O   . GLY D 1 82  ? 116.746 126.934 125.076 1.00 37.63 ? 82  GLY D O   1 
ATOM   10279 N N   . PRO D 1 83  ? 114.801 127.735 125.831 1.00 41.45 ? 83  PRO D N   1 
ATOM   10280 C CA  . PRO D 1 83  ? 114.471 128.325 124.535 1.00 41.45 ? 83  PRO D CA  1 
ATOM   10281 C C   . PRO D 1 83  ? 115.449 129.419 124.146 1.00 41.45 ? 83  PRO D C   1 
ATOM   10282 O O   . PRO D 1 83  ? 116.223 129.912 124.966 1.00 41.45 ? 83  PRO D O   1 
ATOM   10283 C CB  . PRO D 1 83  ? 113.064 128.878 124.749 1.00 41.45 ? 83  PRO D CB  1 
ATOM   10284 C CG  . PRO D 1 83  ? 112.980 129.113 126.194 1.00 41.45 ? 83  PRO D CG  1 
ATOM   10285 C CD  . PRO D 1 83  ? 113.802 128.060 126.855 1.00 41.45 ? 83  PRO D CD  1 
ATOM   10286 N N   . PHE D 1 84  ? 115.436 129.821 122.857 1.00 40.68 ? 84  PHE D N   1 
ATOM   10287 C CA  . PHE D 1 84  ? 116.408 130.817 122.281 1.00 40.68 ? 84  PHE D CA  1 
ATOM   10288 C C   . PHE D 1 84  ? 115.886 132.210 122.391 1.00 40.68 ? 84  PHE D C   1 
ATOM   10289 O O   . PHE D 1 84  ? 114.711 132.452 122.207 1.00 40.68 ? 84  PHE D O   1 
ATOM   10290 C CB  . PHE D 1 84  ? 116.711 130.483 120.808 1.00 40.68 ? 84  PHE D CB  1 
ATOM   10291 C CG  . PHE D 1 84  ? 117.722 131.365 120.164 1.00 40.68 ? 84  PHE D CG  1 
ATOM   10292 C CD1 . PHE D 1 84  ? 119.047 131.195 120.417 1.00 40.68 ? 84  PHE D CD1 1 
ATOM   10293 C CD2 . PHE D 1 84  ? 117.341 132.341 119.282 1.00 40.68 ? 84  PHE D CD2 1 
ATOM   10294 C CE1 . PHE D 1 84  ? 119.982 131.999 119.839 1.00 40.68 ? 84  PHE D CE1 1 
ATOM   10295 C CE2 . PHE D 1 84  ? 118.274 133.154 118.692 1.00 40.68 ? 84  PHE D CE2 1 
ATOM   10296 C CZ  . PHE D 1 84  ? 119.598 132.981 118.973 1.00 40.68 ? 84  PHE D CZ  1 
ATOM   10297 N N   . PRO D 1 85  ? 116.780 133.170 122.716 1.00 42.32 ? 85  PRO D N   1 
ATOM   10298 C CA  . PRO D 1 85  ? 116.146 134.442 122.889 1.00 42.32 ? 85  PRO D CA  1 
ATOM   10299 C C   . PRO D 1 85  ? 115.594 135.038 121.629 1.00 42.32 ? 85  PRO D C   1 
ATOM   10300 O O   . PRO D 1 85  ? 116.328 135.327 120.709 1.00 42.32 ? 85  PRO D O   1 
ATOM   10301 C CB  . PRO D 1 85  ? 117.259 135.284 123.444 1.00 42.32 ? 85  PRO D CB  1 
ATOM   10302 C CG  . PRO D 1 85  ? 118.503 134.643 123.025 1.00 42.32 ? 85  PRO D CG  1 
ATOM   10303 C CD  . PRO D 1 85  ? 118.169 133.228 123.197 1.00 42.32 ? 85  PRO D CD  1 
ATOM   10304 N N   . ASN D 1 86  ? 114.305 135.240 121.563 1.00 53.10 ? 86  ASN D N   1 
ATOM   10305 C CA  . ASN D 1 86  ? 113.753 135.939 120.431 1.00 53.10 ? 86  ASN D CA  1 
ATOM   10306 C C   . ASN D 1 86  ? 113.970 137.439 120.635 1.00 53.10 ? 86  ASN D C   1 
ATOM   10307 O O   . ASN D 1 86  ? 114.502 137.840 121.648 1.00 53.10 ? 86  ASN D O   1 
ATOM   10308 C CB  . ASN D 1 86  ? 112.311 135.511 120.050 1.00 53.10 ? 86  ASN D CB  1 
ATOM   10309 C CG  . ASN D 1 86  ? 111.233 136.022 120.986 1.00 53.10 ? 86  ASN D CG  1 
ATOM   10310 O OD1 . ASN D 1 86  ? 111.313 137.102 121.547 1.00 53.10 ? 86  ASN D OD1 1 
ATOM   10311 N ND2 . ASN D 1 86  ? 110.172 135.248 121.102 1.00 53.10 ? 86  ASN D ND2 1 
ATOM   10312 N N   . SER D 1 87  ? 113.576 138.282 119.697 1.00 58.09 ? 87  SER D N   1 
ATOM   10313 C CA  . SER D 1 87  ? 113.875 139.716 119.761 1.00 58.09 ? 87  SER D CA  1 
ATOM   10314 C C   . SER D 1 87  ? 113.396 140.556 120.931 1.00 58.09 ? 87  SER D C   1 
ATOM   10315 O O   . SER D 1 87  ? 114.136 141.388 121.438 1.00 58.09 ? 87  SER D O   1 
ATOM   10316 C CB  . SER D 1 87  ? 113.264 140.329 118.530 1.00 58.09 ? 87  SER D CB  1 
ATOM   10317 O OG  . SER D 1 87  ? 111.871 140.086 118.502 1.00 58.09 ? 87  SER D OG  1 
ATOM   10318 N N   . ASN D 1 88  ? 112.168 140.373 121.363 1.00 58.07 ? 88  ASN D N   1 
ATOM   10319 C CA  . ASN D 1 88  ? 111.724 141.082 122.529 1.00 58.07 ? 88  ASN D CA  1 
ATOM   10320 C C   . ASN D 1 88  ? 111.964 140.176 123.698 1.00 58.07 ? 88  ASN D C   1 
ATOM   10321 O O   . ASN D 1 88  ? 111.688 140.565 124.825 1.00 58.07 ? 88  ASN D O   1 
ATOM   10322 C CB  . ASN D 1 88  ? 110.251 141.414 122.419 1.00 58.07 ? 88  ASN D CB  1 
ATOM   10323 C CG  . ASN D 1 88  ? 109.418 140.275 121.885 1.00 58.07 ? 88  ASN D CG  1 
ATOM   10324 O OD1 . ASN D 1 88  ? 109.703 139.716 120.831 1.00 58.07 ? 88  ASN D OD1 1 
ATOM   10325 N ND2 . ASN D 1 88  ? 108.342 139.964 122.585 1.00 58.07 ? 88  ASN D ND2 1 
ATOM   10326 N N   . ALA D 1 89  ? 112.484 138.978 123.456 1.00 54.57 ? 89  ALA D N   1 
ATOM   10327 C CA  . ALA D 1 89  ? 112.664 137.956 124.503 1.00 54.57 ? 89  ALA D CA  1 
ATOM   10328 C C   . ALA D 1 89  ? 111.403 137.583 125.242 1.00 54.57 ? 89  ALA D C   1 
ATOM   10329 O O   . ALA D 1 89  ? 111.425 137.415 126.436 1.00 54.57 ? 89  ALA D O   1 
ATOM   10330 C CB  . ALA D 1 89  ? 113.829 138.235 125.427 1.00 54.57 ? 89  ALA D CB  1 
ATOM   10331 N N   . SER D 1 90  ? 110.292 137.498 124.541 1.00 54.90 ? 90  SER D N   1 
ATOM   10332 C CA  . SER D 1 90  ? 109.069 137.018 125.145 1.00 54.90 ? 90  SER D CA  1 
ATOM   10333 C C   . SER D 1 90  ? 109.131 135.568 125.521 1.00 54.90 ? 90  SER D C   1 
ATOM   10334 O O   . SER D 1 90  ? 108.554 135.172 126.507 1.00 54.90 ? 90  SER D O   1 
ATOM   10335 C CB  . SER D 1 90  ? 107.945 137.172 124.154 1.00 54.90 ? 90  SER D CB  1 
ATOM   10336 O OG  . SER D 1 90  ? 108.237 136.503 122.949 1.00 54.90 ? 90  SER D OG  1 
ATOM   10337 N N   . ASN D 1 91  ? 109.763 134.747 124.697 1.00 50.70 ? 91  ASN D N   1 
ATOM   10338 C CA  . ASN D 1 91  ? 109.826 133.329 124.920 1.00 50.70 ? 91  ASN D CA  1 
ATOM   10339 C C   . ASN D 1 91  ? 110.663 132.894 126.079 1.00 50.70 ? 91  ASN D C   1 
ATOM   10340 O O   . ASN D 1 91  ? 110.713 131.724 126.379 1.00 50.70 ? 91  ASN D O   1 
ATOM   10341 C CB  . ASN D 1 91  ? 110.296 132.661 123.653 1.00 50.70 ? 91  ASN D CB  1 
ATOM   10342 C CG  . ASN D 1 91  ? 111.744 132.904 123.346 1.00 50.70 ? 91  ASN D CG  1 
ATOM   10343 O OD1 . ASN D 1 91  ? 112.360 133.855 123.813 1.00 50.70 ? 91  ASN D OD1 1 
ATOM   10344 N ND2 . ASN D 1 91  ? 112.293 132.038 122.515 1.00 50.70 ? 91  ASN D ND2 1 
ATOM   10345 N N   . ILE D 1 92  ? 111.347 133.802 126.730 1.00 47.30 ? 92  ILE D N   1 
ATOM   10346 C CA  . ILE D 1 92  ? 112.074 133.440 127.941 1.00 47.30 ? 92  ILE D CA  1 
ATOM   10347 C C   . ILE D 1 92  ? 111.118 133.535 129.126 1.00 47.30 ? 92  ILE D C   1 
ATOM   10348 O O   . ILE D 1 92  ? 110.755 134.632 129.554 1.00 47.30 ? 92  ILE D O   1 
ATOM   10349 C CB  . ILE D 1 92  ? 113.293 134.339 128.145 1.00 47.30 ? 92  ILE D CB  1 
ATOM   10350 C CG1 . ILE D 1 92  ? 114.233 134.229 126.947 1.00 47.30 ? 92  ILE D CG1 1 
ATOM   10351 C CG2 . ILE D 1 92  ? 113.994 133.989 129.426 1.00 47.30 ? 92  ILE D CG2 1 
ATOM   10352 C CD1 . ILE D 1 92  ? 114.811 132.859 126.737 1.00 47.30 ? 92  ILE D CD1 1 
ATOM   10353 N N   . THR D 1 93  ? 110.714 132.387 129.668 1.00 45.01 ? 93  THR D N   1 
ATOM   10354 C CA  . THR D 1 93  ? 109.808 132.354 130.805 1.00 45.01 ? 93  THR D CA  1 
ATOM   10355 C C   . THR D 1 93  ? 110.491 132.015 132.118 1.00 45.01 ? 93  THR D C   1 
ATOM   10356 O O   . THR D 1 93  ? 109.865 132.155 133.170 1.00 45.01 ? 93  THR D O   1 
ATOM   10357 C CB  . THR D 1 93  ? 108.680 131.347 130.568 1.00 45.01 ? 93  THR D CB  1 
ATOM   10358 O OG1 . THR D 1 93  ? 109.190 130.024 130.724 1.00 45.01 ? 93  THR D OG1 1 
ATOM   10359 C CG2 . THR D 1 93  ? 108.121 131.495 129.178 1.00 45.01 ? 93  THR D CG2 1 
ATOM   10360 N N   . TRP D 1 94  ? 111.740 131.572 132.091 1.00 42.83 ? 94  TRP D N   1 
ATOM   10361 C CA  . TRP D 1 94  ? 112.488 131.250 133.301 1.00 42.83 ? 94  TRP D CA  1 
ATOM   10362 C C   . TRP D 1 94  ? 113.347 132.463 133.630 1.00 42.83 ? 94  TRP D C   1 
ATOM   10363 O O   . TRP D 1 94  ? 114.462 132.610 133.134 1.00 42.83 ? 94  TRP D O   1 
ATOM   10364 C CB  . TRP D 1 94  ? 113.316 129.992 133.094 1.00 42.83 ? 94  TRP D CB  1 
ATOM   10365 C CG  . TRP D 1 94  ? 114.234 129.651 134.214 1.00 42.83 ? 94  TRP D CG  1 
ATOM   10366 C CD1 . TRP D 1 94  ? 115.577 129.830 134.245 1.00 42.83 ? 94  TRP D CD1 1 
ATOM   10367 C CD2 . TRP D 1 94  ? 113.881 129.044 135.457 1.00 42.83 ? 94  TRP D CD2 1 
ATOM   10368 N NE1 . TRP D 1 94  ? 116.086 129.384 135.434 1.00 42.83 ? 94  TRP D NE1 1 
ATOM   10369 C CE2 . TRP D 1 94  ? 115.061 128.898 136.198 1.00 42.83 ? 94  TRP D CE2 1 
ATOM   10370 C CE3 . TRP D 1 94  ? 112.681 128.616 136.018 1.00 42.83 ? 94  TRP D CE3 1 
ATOM   10371 C CZ2 . TRP D 1 94  ? 115.075 128.343 137.468 1.00 42.83 ? 94  TRP D CZ2 1 
ATOM   10372 C CZ3 . TRP D 1 94  ? 112.698 128.068 137.276 1.00 42.83 ? 94  TRP D CZ3 1 
ATOM   10373 C CH2 . TRP D 1 94  ? 113.885 127.936 137.988 1.00 42.83 ? 94  TRP D CH2 1 
ATOM   10374 N N   . THR D 1 95  ? 112.821 133.329 134.489 1.00 48.23 ? 95  THR D N   1 
ATOM   10375 C CA  . THR D 1 95  ? 113.397 134.644 134.720 1.00 48.23 ? 95  THR D CA  1 
ATOM   10376 C C   . THR D 1 95  ? 114.801 134.551 135.300 1.00 48.23 ? 95  THR D C   1 
ATOM   10377 O O   . THR D 1 95  ? 115.218 133.524 135.831 1.00 48.23 ? 95  THR D O   1 
ATOM   10378 C CB  . THR D 1 95  ? 112.515 135.437 135.669 1.00 48.23 ? 95  THR D CB  1 
ATOM   10379 O OG1 . THR D 1 95  ? 112.673 134.922 136.993 1.00 48.23 ? 95  THR D OG1 1 
ATOM   10380 C CG2 . THR D 1 95  ? 111.066 135.301 135.260 1.00 48.23 ? 95  THR D CG2 1 
ATOM   10381 N N   . SER D 1 96  ? 115.527 135.660 135.205 1.00 51.12 ? 96  SER D N   1 
ATOM   10382 C CA  . SER D 1 96  ? 116.919 135.723 135.627 1.00 51.12 ? 96  SER D CA  1 
ATOM   10383 C C   . SER D 1 96  ? 117.443 137.152 135.567 1.00 51.12 ? 96  SER D C   1 
ATOM   10384 O O   . SER D 1 96  ? 116.954 137.963 134.772 1.00 51.12 ? 96  SER D O   1 
ATOM   10385 C CB  . SER D 1 96  ? 117.780 134.816 134.747 1.00 51.12 ? 96  SER D CB  1 
ATOM   10386 O OG  . SER D 1 96  ? 119.147 134.903 135.092 1.00 51.12 ? 96  SER D OG  1 
ATOM   10387 N N   . PRO D 1 97  ? 118.435 137.502 136.388 1.00 51.94 ? 97  PRO D N   1 
ATOM   10388 C CA  . PRO D 1 97  ? 119.123 138.785 136.214 1.00 51.94 ? 97  PRO D CA  1 
ATOM   10389 C C   . PRO D 1 97  ? 120.160 138.779 135.105 1.00 51.94 ? 97  PRO D C   1 
ATOM   10390 O O   . PRO D 1 97  ? 120.733 139.837 134.815 1.00 51.94 ? 97  PRO D O   1 
ATOM   10391 C CB  . PRO D 1 97  ? 119.795 139.012 137.577 1.00 51.94 ? 97  PRO D CB  1 
ATOM   10392 C CG  . PRO D 1 97  ? 119.258 137.949 138.481 1.00 51.94 ? 97  PRO D CG  1 
ATOM   10393 C CD  . PRO D 1 97  ? 118.868 136.820 137.612 1.00 51.94 ? 97  PRO D CD  1 
ATOM   10394 N N   . PHE D 1 98  ? 120.436 137.636 134.498 1.00 51.30 ? 98  PHE D N   1 
ATOM   10395 C CA  . PHE D 1 98  ? 121.380 137.522 133.401 1.00 51.30 ? 98  PHE D CA  1 
ATOM   10396 C C   . PHE D 1 98  ? 120.649 137.257 132.096 1.00 51.30 ? 98  PHE D C   1 
ATOM   10397 O O   . PHE D 1 98  ? 119.479 136.868 132.094 1.00 51.30 ? 98  PHE D O   1 
ATOM   10398 C CB  . PHE D 1 98  ? 122.375 136.395 133.677 1.00 51.30 ? 98  PHE D CB  1 
ATOM   10399 C CG  . PHE D 1 98  ? 122.778 136.291 135.108 1.00 51.30 ? 98  PHE D CG  1 
ATOM   10400 C CD1 . PHE D 1 98  ? 123.401 137.345 135.740 1.00 51.30 ? 98  PHE D CD1 1 
ATOM   10401 C CD2 . PHE D 1 98  ? 122.531 135.141 135.825 1.00 51.30 ? 98  PHE D CD2 1 
ATOM   10402 C CE1 . PHE D 1 98  ? 123.772 137.250 137.057 1.00 51.30 ? 98  PHE D CE1 1 
ATOM   10403 C CE2 . PHE D 1 98  ? 122.900 135.042 137.144 1.00 51.30 ? 98  PHE D CE2 1 
ATOM   10404 C CZ  . PHE D 1 98  ? 123.520 136.096 137.760 1.00 51.30 ? 98  PHE D CZ  1 
ATOM   10405 N N   . PRO D 1 99  ? 121.300 137.477 130.959 1.00 48.89 ? 99  PRO D N   1 
ATOM   10406 C CA  . PRO D 1 99  ? 120.675 137.150 129.678 1.00 48.89 ? 99  PRO D CA  1 
ATOM   10407 C C   . PRO D 1 99  ? 120.599 135.648 129.479 1.00 48.89 ? 99  PRO D C   1 
ATOM   10408 O O   . PRO D 1 99  ? 121.365 134.891 130.093 1.00 48.89 ? 99  PRO D O   1 
ATOM   10409 C CB  . PRO D 1 99  ? 121.611 137.805 128.654 1.00 48.89 ? 99  PRO D CB  1 
ATOM   10410 C CG  . PRO D 1 99  ? 122.903 137.929 129.355 1.00 48.89 ? 99  PRO D CG  1 
ATOM   10411 C CD  . PRO D 1 99  ? 122.565 138.208 130.775 1.00 48.89 ? 99  PRO D CD  1 
ATOM   10412 N N   . PRO D 1 100 ? 119.687 135.177 128.633 1.00 44.51 ? 100 PRO D N   1 
ATOM   10413 C CA  . PRO D 1 100 ? 119.552 133.734 128.421 1.00 44.51 ? 100 PRO D CA  1 
ATOM   10414 C C   . PRO D 1 100 ? 120.796 133.125 127.796 1.00 44.51 ? 100 PRO D C   1 
ATOM   10415 O O   . PRO D 1 100 ? 121.609 133.806 127.172 1.00 44.51 ? 100 PRO D O   1 
ATOM   10416 C CB  . PRO D 1 100 ? 118.352 133.626 127.478 1.00 44.51 ? 100 PRO D CB  1 
ATOM   10417 C CG  . PRO D 1 100 ? 117.607 134.867 127.688 1.00 44.51 ? 100 PRO D CG  1 
ATOM   10418 C CD  . PRO D 1 100 ? 118.614 135.927 127.974 1.00 44.51 ? 100 PRO D CD  1 
ATOM   10419 N N   . GLY D 1 101 ? 120.932 131.818 127.971 1.00 40.39 ? 101 GLY D N   1 
ATOM   10420 C CA  . GLY D 1 101 ? 122.065 131.100 127.455 1.00 40.39 ? 101 GLY D CA  1 
ATOM   10421 C C   . GLY D 1 101 ? 123.034 130.770 128.559 1.00 40.39 ? 101 GLY D C   1 
ATOM   10422 O O   . GLY D 1 101 ? 122.721 130.885 129.744 1.00 40.39 ? 101 GLY D O   1 
ATOM   10423 N N   . PRO D 1 102 ? 124.232 130.342 128.191 1.00 38.44 ? 102 PRO D N   1 
ATOM   10424 C CA  . PRO D 1 102 ? 125.245 130.057 129.202 1.00 38.44 ? 102 PRO D CA  1 
ATOM   10425 C C   . PRO D 1 102 ? 125.513 131.269 130.072 1.00 38.44 ? 102 PRO D C   1 
ATOM   10426 O O   . PRO D 1 102 ? 125.411 132.413 129.632 1.00 38.44 ? 102 PRO D O   1 
ATOM   10427 C CB  . PRO D 1 102 ? 126.475 129.686 128.374 1.00 38.44 ? 102 PRO D CB  1 
ATOM   10428 C CG  . PRO D 1 102 ? 125.932 129.217 127.105 1.00 38.44 ? 102 PRO D CG  1 
ATOM   10429 C CD  . PRO D 1 102 ? 124.681 129.979 126.843 1.00 38.44 ? 102 PRO D CD  1 
ATOM   10430 N N   . LEU D 1 103 ? 125.843 131.006 131.329 1.00 41.70 ? 103 LEU D N   1 
ATOM   10431 C CA  . LEU D 1 103 ? 126.296 132.069 132.203 1.00 41.70 ? 103 LEU D CA  1 
ATOM   10432 C C   . LEU D 1 103 ? 127.665 132.569 131.803 1.00 41.70 ? 103 LEU D C   1 
ATOM   10433 O O   . LEU D 1 103 ? 128.049 133.672 132.197 1.00 41.70 ? 103 LEU D O   1 
ATOM   10434 C CB  . LEU D 1 103 ? 126.339 131.591 133.649 1.00 41.70 ? 103 LEU D CB  1 
ATOM   10435 C CG  . LEU D 1 103 ? 125.011 131.139 134.240 1.00 41.70 ? 103 LEU D CG  1 
ATOM   10436 C CD1 . LEU D 1 103 ? 125.208 130.679 135.665 1.00 41.70 ? 103 LEU D CD1 1 
ATOM   10437 C CD2 . LEU D 1 103 ? 123.992 132.243 134.167 1.00 41.70 ? 103 LEU D CD2 1 
ATOM   10438 N N   . GLU D 1 104 ? 128.399 131.786 131.027 1.00 47.49 ? 104 GLU D N   1 
ATOM   10439 C CA  . GLU D 1 104 ? 129.739 132.155 130.606 1.00 47.49 ? 104 GLU D CA  1 
ATOM   10440 C C   . GLU D 1 104 ? 130.242 131.084 129.651 1.00 47.49 ? 104 GLU D C   1 
ATOM   10441 O O   . GLU D 1 104 ? 129.698 129.981 129.578 1.00 47.49 ? 104 GLU D O   1 
ATOM   10442 C CB  . GLU D 1 104 ? 130.681 132.285 131.795 1.00 47.49 ? 104 GLU D CB  1 
ATOM   10443 C CG  . GLU D 1 104 ? 130.948 130.957 132.467 1.00 47.49 ? 104 GLU D CG  1 
ATOM   10444 C CD  . GLU D 1 104 ? 131.099 131.082 133.963 1.00 47.49 ? 104 GLU D CD  1 
ATOM   10445 O OE1 . GLU D 1 104 ? 130.937 132.198 134.486 1.00 47.49 ? 104 GLU D OE1 1 
ATOM   10446 O OE2 . GLU D 1 104 ? 131.389 130.069 134.624 1.00 47.49 ? 104 GLU D OE2 1 
ATOM   10447 N N   . ALA D 1 105 ? 131.274 131.442 128.900 1.00 45.53 ? 105 ALA D N   1 
ATOM   10448 C CA  . ALA D 1 105 ? 132.114 130.500 128.181 1.00 45.53 ? 105 ALA D CA  1 
ATOM   10449 C C   . ALA D 1 105 ? 133.527 130.875 128.558 1.00 45.53 ? 105 ALA D C   1 
ATOM   10450 O O   . ALA D 1 105 ? 133.985 131.969 128.227 1.00 45.53 ? 105 ALA D O   1 
ATOM   10451 C CB  . ALA D 1 105 ? 131.909 130.579 126.672 1.00 45.53 ? 105 ALA D CB  1 
ATOM   10452 N N   . SER D 1 106 ? 134.210 129.988 129.243 1.00 47.66 ? 106 SER D N   1 
ATOM   10453 C CA  . SER D 1 106 ? 135.177 130.404 130.240 1.00 47.66 ? 106 SER D CA  1 
ATOM   10454 C C   . SER D 1 106 ? 136.566 129.829 130.027 1.00 47.66 ? 106 SER D C   1 
ATOM   10455 O O   . SER D 1 106 ? 137.144 129.223 130.926 1.00 47.66 ? 106 SER D O   1 
ATOM   10456 C CB  . SER D 1 106 ? 134.639 130.081 131.628 1.00 47.66 ? 106 SER D CB  1 
ATOM   10457 O OG  . SER D 1 106 ? 134.164 128.756 131.719 1.00 47.66 ? 106 SER D OG  1 
ATOM   10458 N N   . VAL D 1 107 ? 137.117 130.029 128.834 1.00 54.38 ? 107 VAL D N   1 
ATOM   10459 C CA  . VAL D 1 107 ? 138.498 129.664 128.553 1.00 54.38 ? 107 VAL D CA  1 
ATOM   10460 C C   . VAL D 1 107 ? 139.388 130.129 129.694 1.00 54.38 ? 107 VAL D C   1 
ATOM   10461 O O   . VAL D 1 107 ? 139.429 131.319 130.020 1.00 54.38 ? 107 VAL D O   1 
ATOM   10462 C CB  . VAL D 1 107 ? 138.980 130.283 127.232 1.00 54.38 ? 107 VAL D CB  1 
ATOM   10463 C CG1 . VAL D 1 107 ? 140.453 130.039 127.057 1.00 54.38 ? 107 VAL D CG1 1 
ATOM   10464 C CG2 . VAL D 1 107 ? 138.206 129.720 126.083 1.00 54.38 ? 107 VAL D CG2 1 
ATOM   10465 N N   . ASN D 1 108 ? 140.115 129.197 130.295 1.00 61.97 ? 108 ASN D N   1 
ATOM   10466 C CA  . ASN D 1 108 ? 141.019 129.487 131.392 1.00 61.97 ? 108 ASN D CA  1 
ATOM   10467 C C   . ASN D 1 108 ? 142.456 129.300 130.949 1.00 61.97 ? 108 ASN D C   1 
ATOM   10468 O O   . ASN D 1 108 ? 142.767 128.382 130.182 1.00 61.97 ? 108 ASN D O   1 
ATOM   10469 C CB  . ASN D 1 108 ? 140.754 128.580 132.582 1.00 61.97 ? 108 ASN D CB  1 
ATOM   10470 C CG  . ASN D 1 108 ? 141.859 128.638 133.603 1.00 61.97 ? 108 ASN D CG  1 
ATOM   10471 O OD1 . ASN D 1 108 ? 142.646 129.581 133.639 1.00 61.97 ? 108 ASN D OD1 1 
ATOM   10472 N ND2 . ASN D 1 108 ? 141.954 127.603 134.415 1.00 61.97 ? 108 ASN D ND2 1 
ATOM   10473 N N   . TYR D 1 109 ? 143.326 130.149 131.492 1.00 66.85 ? 109 TYR D N   1 
ATOM   10474 C CA  . TYR D 1 109 ? 144.739 130.192 131.150 1.00 66.85 ? 109 TYR D CA  1 
ATOM   10475 C C   . TYR D 1 109 ? 145.567 129.903 132.391 1.00 66.85 ? 109 TYR D C   1 
ATOM   10476 O O   . TYR D 1 109 ? 145.298 130.455 133.461 1.00 66.85 ? 109 TYR D O   1 
ATOM   10477 C CB  . TYR D 1 109 ? 145.125 131.561 130.574 1.00 66.85 ? 109 TYR D CB  1 
ATOM   10478 C CG  . TYR D 1 109 ? 144.221 132.027 129.461 1.00 66.85 ? 109 TYR D CG  1 
ATOM   10479 C CD1 . TYR D 1 109 ? 143.014 132.652 129.732 1.00 66.85 ? 109 TYR D CD1 1 
ATOM   10480 C CD2 . TYR D 1 109 ? 144.568 131.828 128.140 1.00 66.85 ? 109 TYR D CD2 1 
ATOM   10481 C CE1 . TYR D 1 109 ? 142.188 133.063 128.714 1.00 66.85 ? 109 TYR D CE1 1 
ATOM   10482 C CE2 . TYR D 1 109 ? 143.752 132.243 127.121 1.00 66.85 ? 109 TYR D CE2 1 
ATOM   10483 C CZ  . TYR D 1 109 ? 142.565 132.854 127.410 1.00 66.85 ? 109 TYR D CZ  1 
ATOM   10484 O OH  . TYR D 1 109 ? 141.756 133.258 126.379 1.00 66.85 ? 109 TYR D OH  1 
ATOM   10485 N N   . GLN D 1 110 ? 146.568 129.040 132.247 1.00 72.94 ? 110 GLN D N   1 
ATOM   10486 C CA  . GLN D 1 110 ? 147.547 128.819 133.295 1.00 72.94 ? 110 GLN D CA  1 
ATOM   10487 C C   . GLN D 1 110 ? 148.915 128.723 132.644 1.00 72.94 ? 110 GLN D C   1 
ATOM   10488 O O   . GLN D 1 110 ? 149.036 128.626 131.419 1.00 72.94 ? 110 GLN D O   1 
ATOM   10489 C CB  . GLN D 1 110 ? 147.233 127.560 134.105 1.00 72.94 ? 110 GLN D CB  1 
ATOM   10490 C CG  . GLN D 1 110 ? 145.804 127.446 134.576 1.00 72.94 ? 110 GLN D CG  1 
ATOM   10491 C CD  . GLN D 1 110 ? 145.423 126.022 134.877 1.00 72.94 ? 110 GLN D CD  1 
ATOM   10492 O OE1 . GLN D 1 110 ? 145.917 125.423 135.830 1.00 72.94 ? 110 GLN D OE1 1 
ATOM   10493 N NE2 . GLN D 1 110 ? 144.547 125.460 134.054 1.00 72.94 ? 110 GLN D NE2 1 
ATOM   10494 N N   . ALA D 1 111 ? 149.948 128.705 133.479 1.00 76.65 ? 111 ALA D N   1 
ATOM   10495 C CA  . ALA D 1 111 ? 151.319 128.769 133.001 1.00 76.65 ? 111 ALA D CA  1 
ATOM   10496 C C   . ALA D 1 111 ? 151.663 127.562 132.137 1.00 76.65 ? 111 ALA D C   1 
ATOM   10497 O O   . ALA D 1 111 ? 150.912 126.588 132.049 1.00 76.65 ? 111 ALA D O   1 
ATOM   10498 C CB  . ALA D 1 111 ? 152.290 128.858 134.178 1.00 76.65 ? 111 ALA D CB  1 
ATOM   10499 N N   . GLY D 1 112 ? 152.828 127.639 131.501 1.00 80.72 ? 112 GLY D N   1 
ATOM   10500 C CA  . GLY D 1 112 ? 153.244 126.601 130.578 1.00 80.72 ? 112 GLY D CA  1 
ATOM   10501 C C   . GLY D 1 112 ? 152.332 126.488 129.380 1.00 80.72 ? 112 GLY D C   1 
ATOM   10502 O O   . GLY D 1 112 ? 152.268 125.426 128.748 1.00 80.72 ? 112 GLY D O   1 
ATOM   10503 N N   . GLU D 1 113 ? 151.625 127.569 129.050 1.00 81.14 ? 113 GLU D N   1 
ATOM   10504 C CA  . GLU D 1 113 ? 150.633 127.575 127.980 1.00 81.14 ? 113 GLU D CA  1 
ATOM   10505 C C   . GLU D 1 113 ? 149.640 126.430 128.151 1.00 81.14 ? 113 GLU D C   1 
ATOM   10506 O O   . GLU D 1 113 ? 149.454 125.599 127.261 1.00 81.14 ? 113 GLU D O   1 
ATOM   10507 C CB  . GLU D 1 113 ? 151.298 127.526 126.606 1.00 81.14 ? 113 GLU D CB  1 
ATOM   10508 C CG  . GLU D 1 113 ? 152.029 128.801 126.240 1.00 81.14 ? 113 GLU D CG  1 
ATOM   10509 C CD  . GLU D 1 113 ? 153.188 128.548 125.305 1.00 81.14 ? 113 GLU D CD  1 
ATOM   10510 O OE1 . GLU D 1 113 ? 153.489 127.364 125.045 1.00 81.14 ? 113 GLU D OE1 1 
ATOM   10511 O OE2 . GLU D 1 113 ? 153.804 129.529 124.842 1.00 81.14 ? 113 GLU D OE2 1 
ATOM   10512 N N   . SER D 1 114 ? 149.002 126.380 129.319 1.00 73.93 ? 114 SER D N   1 
ATOM   10513 C CA  . SER D 1 114 ? 147.993 125.366 129.606 1.00 73.93 ? 114 SER D CA  1 
ATOM   10514 C C   . SER D 1 114 ? 146.635 126.053 129.675 1.00 73.93 ? 114 SER D C   1 
ATOM   10515 O O   . SER D 1 114 ? 146.223 126.558 130.721 1.00 73.93 ? 114 SER D O   1 
ATOM   10516 C CB  . SER D 1 114 ? 148.315 124.623 130.897 1.00 73.93 ? 114 SER D CB  1 
ATOM   10517 O OG  . SER D 1 114 ? 147.208 123.852 131.315 1.00 73.93 ? 114 SER D OG  1 
ATOM   10518 N N   . SER D 1 115 ? 145.953 126.091 128.541 1.00 61.61 ? 115 SER D N   1 
ATOM   10519 C CA  . SER D 1 115 ? 144.648 126.713 128.425 1.00 61.61 ? 115 SER D CA  1 
ATOM   10520 C C   . SER D 1 115 ? 143.609 125.641 128.151 1.00 61.61 ? 115 SER D C   1 
ATOM   10521 O O   . SER D 1 115 ? 143.838 124.736 127.350 1.00 61.61 ? 115 SER D O   1 
ATOM   10522 C CB  . SER D 1 115 ? 144.642 127.739 127.301 1.00 61.61 ? 115 SER D CB  1 
ATOM   10523 O OG  . SER D 1 115 ? 144.879 127.103 126.065 1.00 61.61 ? 115 SER D OG  1 
ATOM   10524 N N   . MET D 1 116 ? 142.472 125.740 128.817 1.00 53.23 ? 116 MET D N   1 
ATOM   10525 C CA  . MET D 1 116 ? 141.421 124.760 128.604 1.00 53.23 ? 116 MET D CA  1 
ATOM   10526 C C   . MET D 1 116 ? 140.059 125.435 128.579 1.00 53.23 ? 116 MET D C   1 
ATOM   10527 O O   . MET D 1 116 ? 139.867 126.518 129.133 1.00 53.23 ? 116 MET D O   1 
ATOM   10528 C CB  . MET D 1 116 ? 141.446 123.669 129.662 1.00 53.23 ? 116 MET D CB  1 
ATOM   10529 C CG  . MET D 1 116 ? 141.274 124.165 131.061 1.00 53.23 ? 116 MET D CG  1 
ATOM   10530 S SD  . MET D 1 116 ? 140.627 122.874 132.145 1.00 53.23 ? 116 MET D SD  1 
ATOM   10531 C CE  . MET D 1 116 ? 138.990 122.639 131.456 1.00 53.23 ? 116 MET D CE  1 
ATOM   10532 N N   . PHE D 1 117 ? 139.119 124.779 127.918 1.00 43.86 ? 117 PHE D N   1 
ATOM   10533 C CA  . PHE D 1 117 ? 137.790 125.319 127.689 1.00 43.86 ? 117 PHE D CA  1 
ATOM   10534 C C   . PHE D 1 117 ? 136.820 124.710 128.680 1.00 43.86 ? 117 PHE D C   1 
ATOM   10535 O O   . PHE D 1 117 ? 136.901 123.520 129.010 1.00 43.86 ? 117 PHE D O   1 
ATOM   10536 C CB  . PHE D 1 117 ? 137.327 125.040 126.260 1.00 43.86 ? 117 PHE D CB  1 
ATOM   10537 C CG  . PHE D 1 117 ? 135.969 125.598 125.923 1.00 43.86 ? 117 PHE D CG  1 
ATOM   10538 C CD1 . PHE D 1 117 ? 135.828 126.897 125.487 1.00 43.86 ? 117 PHE D CD1 1 
ATOM   10539 C CD2 . PHE D 1 117 ? 134.839 124.807 125.998 1.00 43.86 ? 117 PHE D CD2 1 
ATOM   10540 C CE1 . PHE D 1 117 ? 134.591 127.396 125.164 1.00 43.86 ? 117 PHE D CE1 1 
ATOM   10541 C CE2 . PHE D 1 117 ? 133.602 125.309 125.669 1.00 43.86 ? 117 PHE D CE2 1 
ATOM   10542 C CZ  . PHE D 1 117 ? 133.482 126.598 125.255 1.00 43.86 ? 117 PHE D CZ  1 
ATOM   10543 N N   . ARG D 1 118 ? 135.906 125.530 129.150 1.00 48.95 ? 118 ARG D N   1 
ATOM   10544 C CA  . ARG D 1 118 ? 134.928 125.142 130.137 1.00 48.95 ? 118 ARG D CA  1 
ATOM   10545 C C   . ARG D 1 118 ? 133.744 126.075 129.976 1.00 48.95 ? 118 ARG D C   1 
ATOM   10546 O O   . ARG D 1 118 ? 133.855 127.164 129.415 1.00 48.95 ? 118 ARG D O   1 
ATOM   10547 C CB  . ARG D 1 118 ? 135.522 125.187 131.554 1.00 48.95 ? 118 ARG D CB  1 
ATOM   10548 C CG  . ARG D 1 118 ? 136.045 126.540 131.946 1.00 48.95 ? 118 ARG D CG  1 
ATOM   10549 C CD  . ARG D 1 118 ? 136.670 126.613 133.327 1.00 48.95 ? 118 ARG D CD  1 
ATOM   10550 N NE  . ARG D 1 118 ? 138.103 126.339 133.353 1.00 48.95 ? 118 ARG D NE  1 
ATOM   10551 C CZ  . ARG D 1 118 ? 138.658 125.302 133.971 1.00 48.95 ? 118 ARG D CZ  1 
ATOM   10552 N NH1 . ARG D 1 118 ? 137.901 124.423 134.607 1.00 48.95 ? 118 ARG D NH1 1 
ATOM   10553 N NH2 . ARG D 1 118 ? 139.972 125.142 133.956 1.00 48.95 ? 118 ARG D NH2 1 
ATOM   10554 N N   . PHE D 1 119 ? 132.597 125.639 130.457 1.00 40.09 ? 119 PHE D N   1 
ATOM   10555 C CA  . PHE D 1 119 ? 131.366 126.274 130.017 1.00 40.09 ? 119 PHE D CA  1 
ATOM   10556 C C   . PHE D 1 119 ? 130.299 126.051 131.067 1.00 40.09 ? 119 PHE D C   1 
ATOM   10557 O O   . PHE D 1 119 ? 130.047 124.915 131.458 1.00 40.09 ? 119 PHE D O   1 
ATOM   10558 C CB  . PHE D 1 119 ? 130.993 125.711 128.651 1.00 40.09 ? 119 PHE D CB  1 
ATOM   10559 C CG  . PHE D 1 119 ? 129.565 125.341 128.494 1.00 40.09 ? 119 PHE D CG  1 
ATOM   10560 C CD1 . PHE D 1 119 ? 128.565 126.281 128.547 1.00 40.09 ? 119 PHE D CD1 1 
ATOM   10561 C CD2 . PHE D 1 119 ? 129.231 124.031 128.244 1.00 40.09 ? 119 PHE D CD2 1 
ATOM   10562 C CE1 . PHE D 1 119 ? 127.260 125.908 128.393 1.00 40.09 ? 119 PHE D CE1 1 
ATOM   10563 C CE2 . PHE D 1 119 ? 127.935 123.662 128.085 1.00 40.09 ? 119 PHE D CE2 1 
ATOM   10564 C CZ  . PHE D 1 119 ? 126.948 124.597 128.158 1.00 40.09 ? 119 PHE D CZ  1 
ATOM   10565 N N   . THR D 1 120 ? 129.694 127.132 131.539 1.00 40.18 ? 120 THR D N   1 
ATOM   10566 C CA  . THR D 1 120 ? 128.743 127.081 132.638 1.00 40.18 ? 120 THR D CA  1 
ATOM   10567 C C   . THR D 1 120 ? 127.341 127.289 132.104 1.00 40.18 ? 120 THR D C   1 
ATOM   10568 O O   . THR D 1 120 ? 127.121 128.149 131.251 1.00 40.18 ? 120 THR D O   1 
ATOM   10569 C CB  . THR D 1 120 ? 129.055 128.147 133.684 1.00 40.18 ? 120 THR D CB  1 
ATOM   10570 O OG1 . THR D 1 120 ? 130.389 127.963 134.162 1.00 40.18 ? 120 THR D OG1 1 
ATOM   10571 C CG2 . THR D 1 120 ? 128.105 128.039 134.849 1.00 40.18 ? 120 THR D CG2 1 
ATOM   10572 N N   . ILE D 1 121 ? 126.396 126.519 132.617 1.00 39.16 ? 121 ILE D N   1 
ATOM   10573 C CA  . ILE D 1 121 ? 125.005 126.680 132.246 1.00 39.16 ? 121 ILE D CA  1 
ATOM   10574 C C   . ILE D 1 121 ? 124.143 126.384 133.460 1.00 39.16 ? 121 ILE D C   1 
ATOM   10575 O O   . ILE D 1 121 ? 124.446 125.488 134.254 1.00 39.16 ? 121 ILE D O   1 
ATOM   10576 C CB  . ILE D 1 121 ? 124.641 125.771 131.058 1.00 39.16 ? 121 ILE D CB  1 
ATOM   10577 C CG1 . ILE D 1 121 ? 123.143 125.808 130.789 1.00 39.16 ? 121 ILE D CG1 1 
ATOM   10578 C CG2 . ILE D 1 121 ? 125.095 124.362 131.302 1.00 39.16 ? 121 ILE D CG2 1 
ATOM   10579 C CD1 . ILE D 1 121 ? 122.736 125.031 129.585 1.00 39.16 ? 121 ILE D CD1 1 
ATOM   10580 N N   . GLU D 1 122 ? 123.097 127.159 133.622 1.00 41.56 ? 122 GLU D N   1 
ATOM   10581 C CA  . GLU D 1 122 ? 122.038 126.790 134.537 1.00 41.56 ? 122 GLU D CA  1 
ATOM   10582 C C   . GLU D 1 122 ? 121.057 125.968 133.718 1.00 41.56 ? 122 GLU D C   1 
ATOM   10583 O O   . GLU D 1 122 ? 120.275 126.536 132.950 1.00 41.56 ? 122 GLU D O   1 
ATOM   10584 C CB  . GLU D 1 122 ? 121.392 128.037 135.145 1.00 41.56 ? 122 GLU D CB  1 
ATOM   10585 C CG  . GLU D 1 122 ? 120.575 127.809 136.402 1.00 41.56 ? 122 GLU D CG  1 
ATOM   10586 C CD  . GLU D 1 122 ? 119.078 127.845 136.164 1.00 41.56 ? 122 GLU D CD  1 
ATOM   10587 O OE1 . GLU D 1 122 ? 118.632 128.593 135.271 1.00 41.56 ? 122 GLU D OE1 1 
ATOM   10588 O OE2 . GLU D 1 122 ? 118.341 127.132 136.876 1.00 41.56 ? 122 GLU D OE2 1 
ATOM   10589 N N   . PRO D 1 123 ? 121.095 124.631 133.811 1.00 40.18 ? 123 PRO D N   1 
ATOM   10590 C CA  . PRO D 1 123 ? 120.224 123.812 132.965 1.00 40.18 ? 123 PRO D CA  1 
ATOM   10591 C C   . PRO D 1 123 ? 118.778 124.220 133.084 1.00 40.18 ? 123 PRO D C   1 
ATOM   10592 O O   . PRO D 1 123 ? 118.213 124.204 134.176 1.00 40.18 ? 123 PRO D O   1 
ATOM   10593 C CB  . PRO D 1 123 ? 120.449 122.399 133.501 1.00 40.18 ? 123 PRO D CB  1 
ATOM   10594 C CG  . PRO D 1 123 ? 121.776 122.441 134.100 1.00 40.18 ? 123 PRO D CG  1 
ATOM   10595 C CD  . PRO D 1 123 ? 121.930 123.796 134.687 1.00 40.18 ? 123 PRO D CD  1 
ATOM   10596 N N   . VAL D 1 124 ? 118.181 124.608 131.967 1.00 37.96 ? 124 VAL D N   1 
ATOM   10597 C CA  . VAL D 1 124 ? 116.804 125.067 131.924 1.00 37.96 ? 124 VAL D CA  1 
ATOM   10598 C C   . VAL D 1 124 ? 116.015 124.096 131.069 1.00 37.96 ? 124 VAL D C   1 
ATOM   10599 O O   . VAL D 1 124 ? 116.409 123.797 129.940 1.00 37.96 ? 124 VAL D O   1 
ATOM   10600 C CB  . VAL D 1 124 ? 116.705 126.494 131.366 1.00 37.96 ? 124 VAL D CB  1 
ATOM   10601 C CG1 . VAL D 1 124 ? 115.276 126.862 131.130 1.00 37.96 ? 124 VAL D CG1 1 
ATOM   10602 C CG2 . VAL D 1 124 ? 117.320 127.454 132.321 1.00 37.96 ? 124 VAL D CG2 1 
ATOM   10603 N N   . GLY D 1 125 ? 114.918 123.593 131.606 1.00 39.65 ? 125 GLY D N   1 
ATOM   10604 C CA  . GLY D 1 125 ? 114.045 122.756 130.833 1.00 39.65 ? 125 GLY D CA  1 
ATOM   10605 C C   . GLY D 1 125 ? 113.366 123.570 129.763 1.00 39.65 ? 125 GLY D C   1 
ATOM   10606 O O   . GLY D 1 125 ? 113.243 124.790 129.874 1.00 39.65 ? 125 GLY D O   1 
ATOM   10607 N N   . PRO D 1 126 ? 112.910 122.917 128.698 1.00 39.77 ? 126 PRO D N   1 
ATOM   10608 C CA  . PRO D 1 126 ? 112.198 123.653 127.649 1.00 39.77 ? 126 PRO D CA  1 
ATOM   10609 C C   . PRO D 1 126 ? 110.961 124.351 128.152 1.00 39.77 ? 126 PRO D C   1 
ATOM   10610 O O   . PRO D 1 126 ? 110.434 125.222 127.454 1.00 39.77 ? 126 PRO D O   1 
ATOM   10611 C CB  . PRO D 1 126 ? 111.851 122.562 126.633 1.00 39.77 ? 126 PRO D CB  1 
ATOM   10612 C CG  . PRO D 1 126 ? 111.875 121.315 127.404 1.00 39.77 ? 126 PRO D CG  1 
ATOM   10613 C CD  . PRO D 1 126 ? 112.958 121.479 128.412 1.00 39.77 ? 126 PRO D CD  1 
ATOM   10614 N N   . HIS D 1 127 ? 110.478 124.002 129.343 1.00 45.10 ? 127 HIS D N   1 
ATOM   10615 C CA  . HIS D 1 127 ? 109.312 124.647 129.929 1.00 45.10 ? 127 HIS D CA  1 
ATOM   10616 C C   . HIS D 1 127 ? 109.564 125.077 131.366 1.00 45.10 ? 127 HIS D C   1 
ATOM   10617 O O   . HIS D 1 127 ? 108.616 125.223 132.133 1.00 45.10 ? 127 HIS D O   1 
ATOM   10618 C CB  . HIS D 1 127 ? 108.099 123.724 129.852 1.00 45.10 ? 127 HIS D CB  1 
ATOM   10619 C CG  . HIS D 1 127 ? 107.980 123.011 128.544 1.00 45.10 ? 127 HIS D CG  1 
ATOM   10620 N ND1 . HIS D 1 127 ? 107.806 123.675 127.351 1.00 45.10 ? 127 HIS D ND1 1 
ATOM   10621 C CD2 . HIS D 1 127 ? 108.020 121.694 128.238 1.00 45.10 ? 127 HIS D CD2 1 
ATOM   10622 C CE1 . HIS D 1 127 ? 107.742 122.799 126.366 1.00 45.10 ? 127 HIS D CE1 1 
ATOM   10623 N NE2 . HIS D 1 127 ? 107.870 121.589 126.878 1.00 45.10 ? 127 HIS D NE2 1 
ATOM   10624 N N   . ALA D 1 128 ? 110.821 125.281 131.742 1.00 44.13 ? 128 ALA D N   1 
ATOM   10625 C CA  . ALA D 1 128 ? 111.145 125.701 133.093 1.00 44.13 ? 128 ALA D CA  1 
ATOM   10626 C C   . ALA D 1 128 ? 110.634 127.107 133.352 1.00 44.13 ? 128 ALA D C   1 
ATOM   10627 O O   . ALA D 1 128 ? 110.693 127.979 132.488 1.00 44.13 ? 128 ALA D O   1 
ATOM   10628 C CB  . ALA D 1 128 ? 112.648 125.652 133.317 1.00 44.13 ? 128 ALA D CB  1 
ATOM   10629 N N   . GLY D 1 129 ? 110.140 127.330 134.560 1.00 45.79 ? 129 GLY D N   1 
ATOM   10630 C CA  . GLY D 1 129 ? 109.521 128.595 134.867 1.00 45.79 ? 129 GLY D CA  1 
ATOM   10631 C C   . GLY D 1 129 ? 108.092 128.715 134.411 1.00 45.79 ? 129 GLY D C   1 
ATOM   10632 O O   . GLY D 1 129 ? 107.539 129.818 134.440 1.00 45.79 ? 129 GLY D O   1 
ATOM   10633 N N   . THR D 1 130 ? 107.483 127.621 133.988 1.00 47.52 ? 130 THR D N   1 
ATOM   10634 C CA  . THR D 1 130 ? 106.084 127.548 133.613 1.00 47.52 ? 130 THR D CA  1 
ATOM   10635 C C   . THR D 1 130 ? 105.401 126.505 134.484 1.00 47.52 ? 130 THR D C   1 
ATOM   10636 O O   . THR D 1 130 ? 106.071 125.674 135.103 1.00 47.52 ? 130 THR D O   1 
ATOM   10637 C CB  . THR D 1 130 ? 105.949 127.186 132.130 1.00 47.52 ? 130 THR D CB  1 
ATOM   10638 O OG1 . THR D 1 130 ? 106.751 126.038 131.849 1.00 47.52 ? 130 THR D OG1 1 
ATOM   10639 C CG2 . THR D 1 130 ? 106.421 128.335 131.271 1.00 47.52 ? 130 THR D CG2 1 
ATOM   10640 N N   . PRO D 1 131 ? 104.066 126.518 134.565 1.00 50.69 ? 131 PRO D N   1 
ATOM   10641 C CA  . PRO D 1 131 ? 103.393 125.627 135.521 1.00 50.69 ? 131 PRO D CA  1 
ATOM   10642 C C   . PRO D 1 131 ? 103.640 124.156 135.281 1.00 50.69 ? 131 PRO D C   1 
ATOM   10643 O O   . PRO D 1 131 ? 103.226 123.338 136.108 1.00 50.69 ? 131 PRO D O   1 
ATOM   10644 C CB  . PRO D 1 131 ? 101.913 125.977 135.341 1.00 50.69 ? 131 PRO D CB  1 
ATOM   10645 C CG  . PRO D 1 131 ? 101.923 127.353 134.817 1.00 50.69 ? 131 PRO D CG  1 
ATOM   10646 C CD  . PRO D 1 131 ? 103.107 127.418 133.910 1.00 50.69 ? 131 PRO D CD  1 
ATOM   10647 N N   . ALA D 1 132 ? 104.288 123.783 134.178 1.00 49.84 ? 132 ALA D N   1 
ATOM   10648 C CA  . ALA D 1 132 ? 104.670 122.392 133.977 1.00 49.84 ? 132 ALA D CA  1 
ATOM   10649 C C   . ALA D 1 132 ? 106.013 122.069 134.615 1.00 49.84 ? 132 ALA D C   1 
ATOM   10650 O O   . ALA D 1 132 ? 106.277 120.904 134.924 1.00 49.84 ? 132 ALA D O   1 
ATOM   10651 C CB  . ALA D 1 132 ? 104.713 122.064 132.488 1.00 49.84 ? 132 ALA D CB  1 
ATOM   10652 N N   . ASP D 1 133 ? 106.869 123.068 134.814 1.00 48.19 ? 133 ASP D N   1 
ATOM   10653 C CA  . ASP D 1 133 ? 108.167 122.881 135.464 1.00 48.19 ? 133 ASP D CA  1 
ATOM   10654 C C   . ASP D 1 133 ? 108.520 124.141 136.235 1.00 48.19 ? 133 ASP D C   1 
ATOM   10655 O O   . ASP D 1 133 ? 109.467 124.856 135.897 1.00 48.19 ? 133 ASP D O   1 
ATOM   10656 C CB  . ASP D 1 133 ? 109.245 122.544 134.433 1.00 48.19 ? 133 ASP D CB  1 
ATOM   10657 C CG  . ASP D 1 133 ? 110.510 122.011 135.065 1.00 48.19 ? 133 ASP D CG  1 
ATOM   10658 O OD1 . ASP D 1 133 ? 110.598 121.994 136.307 1.00 48.19 ? 133 ASP D OD1 1 
ATOM   10659 O OD2 . ASP D 1 133 ? 111.420 121.602 134.315 1.00 48.19 ? 133 ASP D OD2 1 
ATOM   10660 N N   . PRO D 1 134 ? 107.782 124.433 137.309 1.00 47.69 ? 134 PRO D N   1 
ATOM   10661 C CA  . PRO D 1 134 ? 107.967 125.718 137.993 1.00 47.69 ? 134 PRO D CA  1 
ATOM   10662 C C   . PRO D 1 134 ? 109.306 125.878 138.681 1.00 47.69 ? 134 PRO D C   1 
ATOM   10663 O O   . PRO D 1 134 ? 109.683 127.013 138.985 1.00 47.69 ? 134 PRO D O   1 
ATOM   10664 C CB  . PRO D 1 134 ? 106.822 125.738 139.009 1.00 47.69 ? 134 PRO D CB  1 
ATOM   10665 C CG  . PRO D 1 134 ? 106.468 124.325 139.205 1.00 47.69 ? 134 PRO D CG  1 
ATOM   10666 C CD  . PRO D 1 134 ? 106.683 123.654 137.897 1.00 47.69 ? 134 PRO D CD  1 
ATOM   10667 N N   . VAL D 1 135 ? 110.041 124.802 138.942 1.00 47.67 ? 135 VAL D N   1 
ATOM   10668 C CA  . VAL D 1 135 ? 111.296 124.913 139.668 1.00 47.67 ? 135 VAL D CA  1 
ATOM   10669 C C   . VAL D 1 135 ? 112.467 124.336 138.893 1.00 47.67 ? 135 VAL D C   1 
ATOM   10670 O O   . VAL D 1 135 ? 113.555 124.201 139.447 1.00 47.67 ? 135 VAL D O   1 
ATOM   10671 C CB  . VAL D 1 135 ? 111.200 124.259 141.056 1.00 47.67 ? 135 VAL D CB  1 
ATOM   10672 C CG1 . VAL D 1 135 ? 110.432 125.155 141.991 1.00 47.67 ? 135 VAL D CG1 1 
ATOM   10673 C CG2 . VAL D 1 135 ? 110.527 122.919 140.943 1.00 47.67 ? 135 VAL D CG2 1 
ATOM   10674 N N   . ASN D 1 136 ? 112.266 123.982 137.627 1.00 44.16 ? 136 ASN D N   1 
ATOM   10675 C CA  . ASN D 1 136 ? 113.351 123.522 136.771 1.00 44.16 ? 136 ASN D CA  1 
ATOM   10676 C C   . ASN D 1 136 ? 114.076 122.336 137.410 1.00 44.16 ? 136 ASN D C   1 
ATOM   10677 O O   . ASN D 1 136 ? 115.280 122.362 137.659 1.00 44.16 ? 136 ASN D O   1 
ATOM   10678 C CB  . ASN D 1 136 ? 114.311 124.675 136.478 1.00 44.16 ? 136 ASN D CB  1 
ATOM   10679 C CG  . ASN D 1 136 ? 115.252 124.378 135.355 1.00 44.16 ? 136 ASN D CG  1 
ATOM   10680 O OD1 . ASN D 1 136 ? 114.897 123.707 134.396 1.00 44.16 ? 136 ASN D OD1 1 
ATOM   10681 N ND2 . ASN D 1 136 ? 116.467 124.880 135.462 1.00 44.16 ? 136 ASN D ND2 1 
ATOM   10682 N N   . GLU D 1 137 ? 113.310 121.282 137.672 1.00 48.38 ? 137 GLU D N   1 
ATOM   10683 C CA  . GLU D 1 137 ? 113.813 120.159 138.451 1.00 48.38 ? 137 GLU D CA  1 
ATOM   10684 C C   . GLU D 1 137 ? 114.568 119.129 137.620 1.00 48.38 ? 137 GLU D C   1 
ATOM   10685 O O   . GLU D 1 137 ? 115.614 118.637 138.051 1.00 48.38 ? 137 GLU D O   1 
ATOM   10686 C CB  . GLU D 1 137 ? 112.653 119.480 139.171 1.00 48.38 ? 137 GLU D CB  1 
ATOM   10687 C CG  . GLU D 1 137 ? 111.410 119.383 138.326 1.00 48.38 ? 137 GLU D CG  1 
ATOM   10688 C CD  . GLU D 1 137 ? 110.407 118.406 138.887 1.00 48.38 ? 137 GLU D CD  1 
ATOM   10689 O OE1 . GLU D 1 137 ? 110.755 117.667 139.829 1.00 48.38 ? 137 GLU D OE1 1 
ATOM   10690 O OE2 . GLU D 1 137 ? 109.268 118.374 138.384 1.00 48.38 ? 137 GLU D OE2 1 
ATOM   10691 N N   . LEU D 1 138 ? 114.063 118.789 136.437 1.00 43.95 ? 138 LEU D N   1 
ATOM   10692 C CA  . LEU D 1 138 ? 114.606 117.654 135.703 1.00 43.95 ? 138 LEU D CA  1 
ATOM   10693 C C   . LEU D 1 138 ? 115.885 118.001 134.964 1.00 43.95 ? 138 LEU D C   1 
ATOM   10694 O O   . LEU D 1 138 ? 116.795 117.175 134.899 1.00 43.95 ? 138 LEU D O   1 
ATOM   10695 C CB  . LEU D 1 138 ? 113.577 117.125 134.713 1.00 43.95 ? 138 LEU D CB  1 
ATOM   10696 C CG  . LEU D 1 138 ? 112.383 116.401 135.314 1.00 43.95 ? 138 LEU D CG  1 
ATOM   10697 C CD1 . LEU D 1 138 ? 111.604 115.723 134.222 1.00 43.95 ? 138 LEU D CD1 1 
ATOM   10698 C CD2 . LEU D 1 138 ? 112.847 115.394 136.331 1.00 43.95 ? 138 LEU D CD2 1 
ATOM   10699 N N   . ALA D 1 139 ? 115.972 119.213 134.417 1.00 42.64 ? 139 ALA D N   1 
ATOM   10700 C CA  . ALA D 1 139 ? 117.007 119.535 133.441 1.00 42.64 ? 139 ALA D CA  1 
ATOM   10701 C C   . ALA D 1 139 ? 118.387 119.100 133.898 1.00 42.64 ? 139 ALA D C   1 
ATOM   10702 O O   . ALA D 1 139 ? 119.142 118.504 133.125 1.00 42.64 ? 139 ALA D O   1 
ATOM   10703 C CB  . ALA D 1 139 ? 116.996 121.029 133.148 1.00 42.64 ? 139 ALA D CB  1 
ATOM   10704 N N   . ALA D 1 140 ? 118.731 119.368 135.155 1.00 42.88 ? 140 ALA D N   1 
ATOM   10705 C CA  . ALA D 1 140 ? 120.058 119.008 135.641 1.00 42.88 ? 140 ALA D CA  1 
ATOM   10706 C C   . ALA D 1 140 ? 120.252 117.499 135.658 1.00 42.88 ? 140 ALA D C   1 
ATOM   10707 O O   . ALA D 1 140 ? 121.316 116.998 135.280 1.00 42.88 ? 140 ALA D O   1 
ATOM   10708 C CB  . ALA D 1 140 ? 120.279 119.592 137.029 1.00 42.88 ? 140 ALA D CB  1 
ATOM   10709 N N   . LYS D 1 141 ? 119.225 116.759 136.072 1.00 44.29 ? 141 LYS D N   1 
ATOM   10710 C CA  . LYS D 1 141 ? 119.341 115.309 136.135 1.00 44.29 ? 141 LYS D CA  1 
ATOM   10711 C C   . LYS D 1 141 ? 119.359 114.690 134.747 1.00 44.29 ? 141 LYS D C   1 
ATOM   10712 O O   . LYS D 1 141 ? 120.085 113.724 134.509 1.00 44.29 ? 141 LYS D O   1 
ATOM   10713 C CB  . LYS D 1 141 ? 118.204 114.737 136.965 1.00 44.29 ? 141 LYS D CB  1 
ATOM   10714 C CG  . LYS D 1 141 ? 118.328 115.049 138.426 1.00 44.29 ? 141 LYS D CG  1 
ATOM   10715 C CD  . LYS D 1 141 ? 117.052 114.715 139.143 1.00 44.29 ? 141 LYS D CD  1 
ATOM   10716 C CE  . LYS D 1 141 ? 117.181 114.961 140.620 1.00 44.29 ? 141 LYS D CE  1 
ATOM   10717 N NZ  . LYS D 1 141 ? 115.862 114.812 141.279 1.00 44.29 ? 141 LYS D NZ  1 
ATOM   10718 N N   . GLN D 1 142 ? 118.559 115.218 133.824 1.00 43.34 ? 142 GLN D N   1 
ATOM   10719 C CA  . GLN D 1 142 ? 118.625 114.757 132.443 1.00 43.34 ? 142 GLN D CA  1 
ATOM   10720 C C   . GLN D 1 142 ? 120.000 115.004 131.852 1.00 43.34 ? 142 GLN D C   1 
ATOM   10721 O O   . GLN D 1 142 ? 120.540 114.151 131.146 1.00 43.34 ? 142 GLN D O   1 
ATOM   10722 C CB  . GLN D 1 142 ? 117.563 115.450 131.604 1.00 43.34 ? 142 GLN D CB  1 
ATOM   10723 C CG  . GLN D 1 142 ? 116.167 115.017 131.911 1.00 43.34 ? 142 GLN D CG  1 
ATOM   10724 C CD  . GLN D 1 142 ? 115.161 115.764 131.094 1.00 43.34 ? 142 GLN D CD  1 
ATOM   10725 O OE1 . GLN D 1 142 ? 115.496 116.727 130.420 1.00 43.34 ? 142 GLN D OE1 1 
ATOM   10726 N NE2 . GLN D 1 142 ? 113.917 115.329 131.144 1.00 43.34 ? 142 GLN D NE2 1 
ATOM   10727 N N   . LEU D 1 143 ? 120.581 116.168 132.125 1.00 44.00 ? 143 LEU D N   1 
ATOM   10728 C CA  . LEU D 1 143 ? 121.930 116.445 131.656 1.00 44.00 ? 143 LEU D CA  1 
ATOM   10729 C C   . LEU D 1 143 ? 122.926 115.462 132.254 1.00 44.00 ? 143 LEU D C   1 
ATOM   10730 O O   . LEU D 1 143 ? 123.773 114.915 131.543 1.00 44.00 ? 143 LEU D O   1 
ATOM   10731 C CB  . LEU D 1 143 ? 122.304 117.882 132.001 1.00 44.00 ? 143 LEU D CB  1 
ATOM   10732 C CG  . LEU D 1 143 ? 123.732 118.332 131.741 1.00 44.00 ? 143 LEU D CG  1 
ATOM   10733 C CD1 . LEU D 1 143 ? 124.055 118.197 130.291 1.00 44.00 ? 143 LEU D CD1 1 
ATOM   10734 C CD2 . LEU D 1 143 ? 123.895 119.759 132.168 1.00 44.00 ? 143 LEU D CD2 1 
ATOM   10735 N N   . MET D 1 144 ? 122.828 115.212 133.563 1.00 48.46 ? 144 MET D N   1 
ATOM   10736 C CA  . MET D 1 144 ? 123.731 114.267 134.218 1.00 48.46 ? 144 MET D CA  1 
ATOM   10737 C C   . MET D 1 144 ? 123.600 112.874 133.622 1.00 48.46 ? 144 MET D C   1 
ATOM   10738 O O   . MET D 1 144 ? 124.599 112.207 133.336 1.00 48.46 ? 144 MET D O   1 
ATOM   10739 C CB  . MET D 1 144 ? 123.439 114.216 135.715 1.00 48.46 ? 144 MET D CB  1 
ATOM   10740 C CG  . MET D 1 144 ? 123.854 115.436 136.493 1.00 48.46 ? 144 MET D CG  1 
ATOM   10741 S SD  . MET D 1 144 ? 123.992 115.090 138.254 1.00 48.46 ? 144 MET D SD  1 
ATOM   10742 C CE  . MET D 1 144 ? 125.214 113.786 138.256 1.00 48.46 ? 144 MET D CE  1 
ATOM   10743 N N   . GLN D 1 145 ? 122.365 112.418 133.437 1.00 46.75 ? 145 GLN D N   1 
ATOM   10744 C CA  . GLN D 1 145 ? 122.112 111.083 132.917 1.00 46.75 ? 145 GLN D CA  1 
ATOM   10745 C C   . GLN D 1 145 ? 122.609 110.936 131.490 1.00 46.75 ? 145 GLN D C   1 
ATOM   10746 O O   . GLN D 1 145 ? 123.293 109.965 131.159 1.00 46.75 ? 145 GLN D O   1 
ATOM   10747 C CB  . GLN D 1 145 ? 120.622 110.789 132.994 1.00 46.75 ? 145 GLN D CB  1 
ATOM   10748 C CG  . GLN D 1 145 ? 120.197 109.620 132.173 1.00 46.75 ? 145 GLN D CG  1 
ATOM   10749 C CD  . GLN D 1 145 ? 118.759 109.274 132.405 1.00 46.75 ? 145 GLN D CD  1 
ATOM   10750 O OE1 . GLN D 1 145 ? 118.119 109.824 133.294 1.00 46.75 ? 145 GLN D OE1 1 
ATOM   10751 N NE2 . GLN D 1 145 ? 118.229 108.369 131.596 1.00 46.75 ? 145 GLN D NE2 1 
ATOM   10752 N N   . ARG D 1 146 ? 122.236 111.870 130.621 1.00 48.57 ? 146 ARG D N   1 
ATOM   10753 C CA  . ARG D 1 146 ? 122.727 111.858 129.254 1.00 48.57 ? 146 ARG D CA  1 
ATOM   10754 C C   . ARG D 1 146 ? 124.242 111.861 129.223 1.00 48.57 ? 146 ARG D C   1 
ATOM   10755 O O   . ARG D 1 146 ? 124.858 111.110 128.462 1.00 48.57 ? 146 ARG D O   1 
ATOM   10756 C CB  . ARG D 1 146 ? 122.168 113.067 128.513 1.00 48.57 ? 146 ARG D CB  1 
ATOM   10757 C CG  . ARG D 1 146 ? 122.410 113.073 127.039 1.00 48.57 ? 146 ARG D CG  1 
ATOM   10758 C CD  . ARG D 1 146 ? 121.585 112.023 126.356 1.00 48.57 ? 146 ARG D CD  1 
ATOM   10759 N NE  . ARG D 1 146 ? 122.423 110.931 125.886 1.00 48.57 ? 146 ARG D NE  1 
ATOM   10760 C CZ  . ARG D 1 146 ? 121.976 109.897 125.188 1.00 48.57 ? 146 ARG D CZ  1 
ATOM   10761 N NH1 . ARG D 1 146 ? 120.693 109.812 124.874 1.00 48.57 ? 146 ARG D NH1 1 
ATOM   10762 N NH2 . ARG D 1 146 ? 122.816 108.949 124.805 1.00 48.57 ? 146 ARG D NH2 1 
ATOM   10763 N N   . LEU D 1 147 ? 124.861 112.675 130.066 1.00 47.22 ? 147 LEU D N   1 
ATOM   10764 C CA  . LEU D 1 147 ? 126.304 112.798 130.036 1.00 47.22 ? 147 LEU D CA  1 
ATOM   10765 C C   . LEU D 1 147 ? 126.976 111.526 130.537 1.00 47.22 ? 147 LEU D C   1 
ATOM   10766 O O   . LEU D 1 147 ? 128.071 111.182 130.083 1.00 47.22 ? 147 LEU D O   1 
ATOM   10767 C CB  . LEU D 1 147 ? 126.709 114.006 130.868 1.00 47.22 ? 147 LEU D CB  1 
ATOM   10768 C CG  . LEU D 1 147 ? 128.099 114.562 130.631 1.00 47.22 ? 147 LEU D CG  1 
ATOM   10769 C CD1 . LEU D 1 147 ? 128.135 115.101 129.236 1.00 47.22 ? 147 LEU D CD1 1 
ATOM   10770 C CD2 . LEU D 1 147 ? 128.375 115.655 131.616 1.00 47.22 ? 147 LEU D CD2 1 
ATOM   10771 N N   . GLY D 1 148 ? 126.340 110.809 131.462 1.00 51.76 ? 148 GLY D N   1 
ATOM   10772 C CA  . GLY D 1 148 ? 126.883 109.528 131.883 1.00 51.76 ? 148 GLY D CA  1 
ATOM   10773 C C   . GLY D 1 148 ? 126.669 108.438 130.851 1.00 51.76 ? 148 GLY D C   1 
ATOM   10774 O O   . GLY D 1 148 ? 127.519 107.565 130.670 1.00 51.76 ? 148 GLY D O   1 
ATOM   10775 N N   . GLN D 1 149 ? 125.528 108.469 130.167 1.00 49.50 ? 149 GLN D N   1 
ATOM   10776 C CA  . GLN D 1 149 ? 125.276 107.526 129.087 1.00 49.50 ? 149 GLN D CA  1 
ATOM   10777 C C   . GLN D 1 149 ? 126.282 107.700 127.960 1.00 49.50 ? 149 GLN D C   1 
ATOM   10778 O O   . GLN D 1 149 ? 126.708 106.720 127.342 1.00 49.50 ? 149 GLN D O   1 
ATOM   10779 C CB  . GLN D 1 149 ? 123.856 107.708 128.565 1.00 49.50 ? 149 GLN D CB  1 
ATOM   10780 C CG  . GLN D 1 149 ? 123.561 106.964 127.295 1.00 49.50 ? 149 GLN D CG  1 
ATOM   10781 C CD  . GLN D 1 149 ? 123.187 105.524 127.542 1.00 49.50 ? 149 GLN D CD  1 
ATOM   10782 O OE1 . GLN D 1 149 ? 122.876 105.136 128.665 1.00 49.50 ? 149 GLN D OE1 1 
ATOM   10783 N NE2 . GLN D 1 149 ? 123.209 104.719 126.487 1.00 49.50 ? 149 GLN D NE2 1 
ATOM   10784 N N   . LEU D 1 150 ? 126.676 108.940 127.674 1.00 49.54 ? 150 LEU D N   1 
ATOM   10785 C CA  . LEU D 1 150 ? 127.676 109.160 126.638 1.00 49.54 ? 150 LEU D CA  1 
ATOM   10786 C C   . LEU D 1 150 ? 129.019 108.577 127.044 1.00 49.54 ? 150 LEU D C   1 
ATOM   10787 O O   . LEU D 1 150 ? 129.645 107.847 126.271 1.00 49.54 ? 150 LEU D O   1 
ATOM   10788 C CB  . LEU D 1 150 ? 127.807 110.650 126.333 1.00 49.54 ? 150 LEU D CB  1 
ATOM   10789 C CG  . LEU D 1 150 ? 126.556 111.302 125.747 1.00 49.54 ? 150 LEU D CG  1 
ATOM   10790 C CD1 . LEU D 1 150 ? 126.836 112.714 125.273 1.00 49.54 ? 150 LEU D CD1 1 
ATOM   10791 C CD2 . LEU D 1 150 ? 125.994 110.456 124.621 1.00 49.54 ? 150 LEU D CD2 1 
ATOM   10792 N N   . GLN D 1 151 ? 129.479 108.885 128.255 1.00 54.06 ? 151 GLN D N   1 
ATOM   10793 C CA  . GLN D 1 151 ? 130.745 108.370 128.775 1.00 54.06 ? 151 GLN D CA  1 
ATOM   10794 C C   . GLN D 1 151 ? 130.460 107.545 130.020 1.00 54.06 ? 151 GLN D C   1 
ATOM   10795 O O   . GLN D 1 151 ? 130.459 108.082 131.136 1.00 54.06 ? 151 GLN D O   1 
ATOM   10796 C CB  . GLN D 1 151 ? 131.717 109.501 129.098 1.00 54.06 ? 151 GLN D CB  1 
ATOM   10797 C CG  . GLN D 1 151 ? 131.859 110.553 128.015 1.00 54.06 ? 151 GLN D CG  1 
ATOM   10798 C CD  . GLN D 1 151 ? 131.107 111.823 128.344 1.00 54.06 ? 151 GLN D CD  1 
ATOM   10799 O OE1 . GLN D 1 151 ? 130.611 111.987 129.453 1.00 54.06 ? 151 GLN D OE1 1 
ATOM   10800 N NE2 . GLN D 1 151 ? 131.032 112.736 127.384 1.00 54.06 ? 151 GLN D NE2 1 
ATOM   10801 N N   . PRO D 1 152 ? 130.207 106.245 129.884 1.00 57.41 ? 152 PRO D N   1 
ATOM   10802 C CA  . PRO D 1 152 ? 129.898 105.435 131.067 1.00 57.41 ? 152 PRO D CA  1 
ATOM   10803 C C   . PRO D 1 152 ? 131.080 105.371 132.018 1.00 57.41 ? 152 PRO D C   1 
ATOM   10804 O O   . PRO D 1 152 ? 132.240 105.376 131.600 1.00 57.41 ? 152 PRO D O   1 
ATOM   10805 C CB  . PRO D 1 152 ? 129.573 104.059 130.480 1.00 57.41 ? 152 PRO D CB  1 
ATOM   10806 C CG  . PRO D 1 152 ? 129.183 104.337 129.074 1.00 57.41 ? 152 PRO D CG  1 
ATOM   10807 C CD  . PRO D 1 152 ? 130.051 105.475 128.643 1.00 57.41 ? 152 PRO D CD  1 
ATOM   10808 N N   . GLY D 1 153 ? 130.772 105.327 133.310 1.00 57.90 ? 153 GLY D N   1 
ATOM   10809 C CA  . GLY D 1 153 ? 131.789 105.332 134.336 1.00 57.90 ? 153 GLY D CA  1 
ATOM   10810 C C   . GLY D 1 153 ? 132.450 106.668 134.577 1.00 57.90 ? 153 GLY D C   1 
ATOM   10811 O O   . GLY D 1 153 ? 133.349 106.752 135.423 1.00 57.90 ? 153 GLY D O   1 
ATOM   10812 N N   . GLY D 1 154 ? 132.035 107.715 133.875 1.00 60.62 ? 154 GLY D N   1 
ATOM   10813 C CA  . GLY D 1 154 ? 132.643 109.017 133.993 1.00 60.62 ? 154 GLY D CA  1 
ATOM   10814 C C   . GLY D 1 154 ? 131.925 110.011 134.871 1.00 60.62 ? 154 GLY D C   1 
ATOM   10815 O O   . GLY D 1 154 ? 132.364 111.159 134.960 1.00 60.62 ? 154 GLY D O   1 
ATOM   10816 N N   . VAL D 1 155 ? 130.830 109.621 135.519 1.00 59.01 ? 155 VAL D N   1 
ATOM   10817 C CA  . VAL D 1 155 ? 130.048 110.523 136.366 1.00 59.01 ? 155 VAL D CA  1 
ATOM   10818 C C   . VAL D 1 155 ? 129.772 109.797 137.669 1.00 59.01 ? 155 VAL D C   1 
ATOM   10819 O O   . VAL D 1 155 ? 128.806 109.035 137.790 1.00 59.01 ? 155 VAL D O   1 
ATOM   10820 C CB  . VAL D 1 155 ? 128.744 110.970 135.695 1.00 59.01 ? 155 VAL D CB  1 
ATOM   10821 C CG1 . VAL D 1 155 ? 127.955 111.853 136.629 1.00 59.01 ? 155 VAL D CG1 1 
ATOM   10822 C CG2 . VAL D 1 155 ? 129.042 111.700 134.409 1.00 59.01 ? 155 VAL D CG2 1 
ATOM   10823 N N   . ASP D 1 156 ? 130.614 110.029 138.676 1.00 60.01 ? 156 ASP D N   1 
ATOM   10824 C CA  . ASP D 1 156 ? 130.376 109.484 140.001 1.00 60.01 ? 156 ASP D CA  1 
ATOM   10825 C C   . ASP D 1 156 ? 129.393 110.369 140.750 1.00 60.01 ? 156 ASP D C   1 
ATOM   10826 O O   . ASP D 1 156 ? 129.519 111.594 140.758 1.00 60.01 ? 156 ASP D O   1 
ATOM   10827 C CB  . ASP D 1 156 ? 131.687 109.368 140.775 1.00 60.01 ? 156 ASP D CB  1 
ATOM   10828 C CG  . ASP D 1 156 ? 131.521 108.672 142.109 1.00 60.01 ? 156 ASP D CG  1 
ATOM   10829 O OD1 . ASP D 1 156 ? 130.407 108.201 142.404 1.00 60.01 ? 156 ASP D OD1 1 
ATOM   10830 O OD2 . ASP D 1 156 ? 132.508 108.593 142.866 1.00 60.01 ? 156 ASP D OD2 1 
ATOM   10831 N N   . SER D 1 157 ? 128.419 109.739 141.399 1.00 54.91 ? 157 SER D N   1 
ATOM   10832 C CA  . SER D 1 157 ? 127.274 110.446 141.951 1.00 54.91 ? 157 SER D CA  1 
ATOM   10833 C C   . SER D 1 157 ? 127.251 110.450 143.474 1.00 54.91 ? 157 SER D C   1 
ATOM   10834 O O   . SER D 1 157 ? 126.191 110.644 144.066 1.00 54.91 ? 157 SER D O   1 
ATOM   10835 C CB  . SER D 1 157 ? 125.985 109.835 141.411 1.00 54.91 ? 157 SER D CB  1 
ATOM   10836 O OG  . SER D 1 157 ? 124.860 110.606 141.784 1.00 54.91 ? 157 SER D OG  1 
ATOM   10837 N N   . THR D 1 158 ? 128.395 110.252 144.124 1.00 57.15 ? 158 THR D N   1 
ATOM   10838 C CA  . THR D 1 158 ? 128.408 110.181 145.581 1.00 57.15 ? 158 THR D CA  1 
ATOM   10839 C C   . THR D 1 158 ? 127.996 111.505 146.212 1.00 57.15 ? 158 THR D C   1 
ATOM   10840 O O   . THR D 1 158 ? 126.965 111.597 146.888 1.00 57.15 ? 158 THR D O   1 
ATOM   10841 C CB  . THR D 1 158 ? 129.790 109.772 146.068 1.00 57.15 ? 158 THR D CB  1 
ATOM   10842 O OG1 . THR D 1 158 ? 130.138 108.508 145.499 1.00 57.15 ? 158 THR D OG1 1 
ATOM   10843 C CG2 . THR D 1 158 ? 129.786 109.654 147.563 1.00 57.15 ? 158 THR D CG2 1 
ATOM   10844 N N   . MET D 1 159 ? 128.796 112.549 145.999 1.00 58.02 ? 159 MET D N   1 
ATOM   10845 C CA  . MET D 1 159 ? 128.555 113.807 146.695 1.00 58.02 ? 159 MET D CA  1 
ATOM   10846 C C   . MET D 1 159 ? 127.236 114.421 146.278 1.00 58.02 ? 159 MET D C   1 
ATOM   10847 O O   . MET D 1 159 ? 126.578 115.090 147.079 1.00 58.02 ? 159 MET D O   1 
ATOM   10848 C CB  . MET D 1 159 ? 129.689 114.786 146.433 1.00 58.02 ? 159 MET D CB  1 
ATOM   10849 C CG  . MET D 1 159 ? 131.056 114.194 146.582 1.00 58.02 ? 159 MET D CG  1 
ATOM   10850 S SD  . MET D 1 159 ? 132.266 115.507 146.587 1.00 58.02 ? 159 MET D SD  1 
ATOM   10851 C CE  . MET D 1 159 ? 131.954 116.200 148.196 1.00 58.02 ? 159 MET D CE  1 
ATOM   10852 N N   . PHE D 1 160 ? 126.848 114.233 145.020 1.00 50.95 ? 160 PHE D N   1 
ATOM   10853 C CA  . PHE D 1 160 ? 125.513 114.640 144.616 1.00 50.95 ? 160 PHE D CA  1 
ATOM   10854 C C   . PHE D 1 160 ? 124.477 113.959 145.485 1.00 50.95 ? 160 PHE D C   1 
ATOM   10855 O O   . PHE D 1 160 ? 123.539 114.601 145.967 1.00 50.95 ? 160 PHE D O   1 
ATOM   10856 C CB  . PHE D 1 160 ? 125.280 114.314 143.142 1.00 50.95 ? 160 PHE D CB  1 
ATOM   10857 C CG  . PHE D 1 160 ? 123.993 114.862 142.599 1.00 50.95 ? 160 PHE D CG  1 
ATOM   10858 C CD1 . PHE D 1 160 ? 122.793 114.233 142.850 1.00 50.95 ? 160 PHE D CD1 1 
ATOM   10859 C CD2 . PHE D 1 160 ? 123.984 116.007 141.838 1.00 50.95 ? 160 PHE D CD2 1 
ATOM   10860 C CE1 . PHE D 1 160 ? 121.619 114.736 142.361 1.00 50.95 ? 160 PHE D CE1 1 
ATOM   10861 C CE2 . PHE D 1 160 ? 122.806 116.511 141.344 1.00 50.95 ? 160 PHE D CE2 1 
ATOM   10862 C CZ  . PHE D 1 160 ? 121.625 115.875 141.608 1.00 50.95 ? 160 PHE D CZ  1 
ATOM   10863 N N   . ASP D 1 161 ? 124.652 112.660 145.722 1.00 56.95 ? 161 ASP D N   1 
ATOM   10864 C CA  . ASP D 1 161 ? 123.694 111.924 146.532 1.00 56.95 ? 161 ASP D CA  1 
ATOM   10865 C C   . ASP D 1 161 ? 123.656 112.458 147.952 1.00 56.95 ? 161 ASP D C   1 
ATOM   10866 O O   . ASP D 1 161 ? 122.586 112.545 148.560 1.00 56.95 ? 161 ASP D O   1 
ATOM   10867 C CB  . ASP D 1 161 ? 124.042 110.440 146.529 1.00 56.95 ? 161 ASP D CB  1 
ATOM   10868 C CG  . ASP D 1 161 ? 123.771 109.780 145.196 1.00 56.95 ? 161 ASP D CG  1 
ATOM   10869 O OD1 . ASP D 1 161 ? 123.027 110.356 144.380 1.00 56.95 ? 161 ASP D OD1 1 
ATOM   10870 O OD2 . ASP D 1 161 ? 124.319 108.684 144.959 1.00 56.95 ? 161 ASP D OD2 1 
ATOM   10871 N N   . HIS D 1 162 ? 124.812 112.837 148.494 1.00 57.58 ? 162 HIS D N   1 
ATOM   10872 C CA  . HIS D 1 162 ? 124.830 113.295 149.878 1.00 57.58 ? 162 HIS D CA  1 
ATOM   10873 C C   . HIS D 1 162 ? 124.234 114.687 150.024 1.00 57.58 ? 162 HIS D C   1 
ATOM   10874 O O   . HIS D 1 162 ? 123.550 114.968 151.012 1.00 57.58 ? 162 HIS D O   1 
ATOM   10875 C CB  . HIS D 1 162 ? 126.244 113.288 150.440 1.00 57.58 ? 162 HIS D CB  1 
ATOM   10876 C CG  . HIS D 1 162 ? 126.310 113.755 151.858 1.00 57.58 ? 162 HIS D CG  1 
ATOM   10877 N ND1 . HIS D 1 162 ? 126.218 112.894 152.928 1.00 57.58 ? 162 HIS D ND1 1 
ATOM   10878 C CD2 . HIS D 1 162 ? 126.413 114.997 152.383 1.00 57.58 ? 162 HIS D CD2 1 
ATOM   10879 C CE1 . HIS D 1 162 ? 126.280 113.584 154.051 1.00 57.58 ? 162 HIS D CE1 1 
ATOM   10880 N NE2 . HIS D 1 162 ? 126.398 114.863 153.748 1.00 57.58 ? 162 HIS D NE2 1 
ATOM   10881 N N   . PHE D 1 163 ? 124.497 115.579 149.070 1.00 53.95 ? 163 PHE D N   1 
ATOM   10882 C CA  . PHE D 1 163 ? 124.161 116.987 149.241 1.00 53.95 ? 163 PHE D CA  1 
ATOM   10883 C C   . PHE D 1 163 ? 122.825 117.383 148.648 1.00 53.95 ? 163 PHE D C   1 
ATOM   10884 O O   . PHE D 1 163 ? 122.241 118.366 149.106 1.00 53.95 ? 163 PHE D O   1 
ATOM   10885 C CB  . PHE D 1 163 ? 125.239 117.869 148.624 1.00 53.95 ? 163 PHE D CB  1 
ATOM   10886 C CG  . PHE D 1 163 ? 126.441 118.015 149.475 1.00 53.95 ? 163 PHE D CG  1 
ATOM   10887 C CD1 . PHE D 1 163 ? 126.392 118.751 150.634 1.00 53.95 ? 163 PHE D CD1 1 
ATOM   10888 C CD2 . PHE D 1 163 ? 127.624 117.411 149.124 1.00 53.95 ? 163 PHE D CD2 1 
ATOM   10889 C CE1 . PHE D 1 163 ? 127.500 118.883 151.422 1.00 53.95 ? 163 PHE D CE1 1 
ATOM   10890 C CE2 . PHE D 1 163 ? 128.735 117.543 149.913 1.00 53.95 ? 163 PHE D CE2 1 
ATOM   10891 C CZ  . PHE D 1 163 ? 128.671 118.278 151.063 1.00 53.95 ? 163 PHE D CZ  1 
ATOM   10892 N N   . TYR D 1 164 ? 122.333 116.677 147.639 1.00 52.60 ? 164 TYR D N   1 
ATOM   10893 C CA  . TYR D 1 164 ? 120.998 116.966 147.135 1.00 52.60 ? 164 TYR D CA  1 
ATOM   10894 C C   . TYR D 1 164 ? 119.936 117.000 148.227 1.00 52.60 ? 164 TYR D C   1 
ATOM   10895 O O   . TYR D 1 164 ? 119.000 117.807 148.107 1.00 52.60 ? 164 TYR D O   1 
ATOM   10896 C CB  . TYR D 1 164 ? 120.632 115.944 146.051 1.00 52.60 ? 164 TYR D CB  1 
ATOM   10897 C CG  . TYR D 1 164 ? 119.337 116.240 145.339 1.00 52.60 ? 164 TYR D CG  1 
ATOM   10898 C CD1 . TYR D 1 164 ? 119.294 117.128 144.283 1.00 52.60 ? 164 TYR D CD1 1 
ATOM   10899 C CD2 . TYR D 1 164 ? 118.160 115.628 145.722 1.00 52.60 ? 164 TYR D CD2 1 
ATOM   10900 C CE1 . TYR D 1 164 ? 118.115 117.401 143.633 1.00 52.60 ? 164 TYR D CE1 1 
ATOM   10901 C CE2 . TYR D 1 164 ? 116.980 115.894 145.075 1.00 52.60 ? 164 TYR D CE2 1 
ATOM   10902 C CZ  . TYR D 1 164 ? 116.963 116.782 144.032 1.00 52.60 ? 164 TYR D CZ  1 
ATOM   10903 O OH  . TYR D 1 164 ? 115.785 117.053 143.381 1.00 52.60 ? 164 TYR D OH  1 
ATOM   10904 N N   . PRO D 1 165 ? 119.991 116.182 149.282 1.00 52.86 ? 165 PRO D N   1 
ATOM   10905 C CA  . PRO D 1 165 ? 118.980 116.329 150.339 1.00 52.86 ? 165 PRO D CA  1 
ATOM   10906 C C   . PRO D 1 165 ? 119.165 117.566 151.198 1.00 52.86 ? 165 PRO D C   1 
ATOM   10907 O O   . PRO D 1 165 ? 118.180 118.229 151.541 1.00 52.86 ? 165 PRO D O   1 
ATOM   10908 C CB  . PRO D 1 165 ? 119.153 115.046 151.158 1.00 52.86 ? 165 PRO D CB  1 
ATOM   10909 C CG  . PRO D 1 165 ? 119.839 114.112 150.265 1.00 52.86 ? 165 PRO D CG  1 
ATOM   10910 C CD  . PRO D 1 165 ? 120.743 114.928 149.445 1.00 52.86 ? 165 PRO D CD  1 
ATOM   10911 N N   . LEU D 1 166 ? 120.402 117.899 151.555 1.00 54.21 ? 166 LEU D N   1 
ATOM   10912 C CA  . LEU D 1 166 ? 120.636 118.934 152.552 1.00 54.21 ? 166 LEU D CA  1 
ATOM   10913 C C   . LEU D 1 166 ? 120.588 120.330 151.949 1.00 54.21 ? 166 LEU D C   1 
ATOM   10914 O O   . LEU D 1 166 ? 119.986 121.239 152.527 1.00 54.21 ? 166 LEU D O   1 
ATOM   10915 C CB  . LEU D 1 166 ? 121.977 118.691 153.230 1.00 54.21 ? 166 LEU D CB  1 
ATOM   10916 C CG  . LEU D 1 166 ? 122.169 117.226 153.599 1.00 54.21 ? 166 LEU D CG  1 
ATOM   10917 C CD1 . LEU D 1 166 ? 123.552 116.975 154.143 1.00 54.21 ? 166 LEU D CD1 1 
ATOM   10918 C CD2 . LEU D 1 166 ? 121.121 116.824 154.606 1.00 54.21 ? 166 LEU D CD2 1 
ATOM   10919 N N   . LEU D 1 167 ? 121.218 120.523 150.794 1.00 56.26 ? 167 LEU D N   1 
ATOM   10920 C CA  . LEU D 1 167 ? 121.295 121.845 150.185 1.00 56.26 ? 167 LEU D CA  1 
ATOM   10921 C C   . LEU D 1 167 ? 120.151 122.126 149.228 1.00 56.26 ? 167 LEU D C   1 
ATOM   10922 O O   . LEU D 1 167 ? 119.465 123.139 149.366 1.00 56.26 ? 167 LEU D O   1 
ATOM   10923 C CB  . LEU D 1 167 ? 122.609 122.000 149.429 1.00 56.26 ? 167 LEU D CB  1 
ATOM   10924 C CG  . LEU D 1 167 ? 123.891 121.913 150.237 1.00 56.26 ? 167 LEU D CG  1 
ATOM   10925 C CD1 . LEU D 1 167 ? 125.057 121.880 149.286 1.00 56.26 ? 167 LEU D CD1 1 
ATOM   10926 C CD2 . LEU D 1 167 ? 124.000 123.086 151.176 1.00 56.26 ? 167 LEU D CD2 1 
ATOM   10927 N N   . CYS D 1 168 ? 119.940 121.260 148.249 1.00 56.66 ? 168 CYS D N   1 
ATOM   10928 C CA  . CYS D 1 168 ? 118.998 121.543 147.186 1.00 56.66 ? 168 CYS D CA  1 
ATOM   10929 C C   . CYS D 1 168 ? 117.575 121.310 147.663 1.00 56.66 ? 168 CYS D C   1 
ATOM   10930 O O   . CYS D 1 168 ? 117.325 120.925 148.805 1.00 56.66 ? 168 CYS D O   1 
ATOM   10931 C CB  . CYS D 1 168 ? 119.305 120.688 145.962 1.00 56.66 ? 168 CYS D CB  1 
ATOM   10932 S SG  . CYS D 1 168 ? 118.223 120.995 144.563 1.00 56.66 ? 168 CYS D SG  1 
ATOM   10933 N N   . VAL D 1 169 ? 116.626 121.558 146.772 1.00 58.92 ? 169 VAL D N   1 
ATOM   10934 C CA  . VAL D 1 169 ? 115.219 121.302 147.027 1.00 58.92 ? 169 VAL D CA  1 
ATOM   10935 C C   . VAL D 1 169 ? 114.642 120.603 145.812 1.00 58.92 ? 169 VAL D C   1 
ATOM   10936 O O   . VAL D 1 169 ? 114.752 121.110 144.691 1.00 58.92 ? 169 VAL D O   1 
ATOM   10937 C CB  . VAL D 1 169 ? 114.443 122.594 147.320 1.00 58.92 ? 169 VAL D CB  1 
ATOM   10938 C CG1 . VAL D 1 169 ? 112.967 122.321 147.263 1.00 58.92 ? 169 VAL D CG1 1 
ATOM   10939 C CG2 . VAL D 1 169 ? 114.816 123.129 148.677 1.00 58.92 ? 169 VAL D CG2 1 
ATOM   10940 N N   . ASP D 1 170 ? 114.032 119.445 146.030 1.00 61.77 ? 170 ASP D N   1 
ATOM   10941 C CA  . ASP D 1 170 ? 113.429 118.695 144.945 1.00 61.77 ? 170 ASP D CA  1 
ATOM   10942 C C   . ASP D 1 170 ? 112.155 119.384 144.476 1.00 61.77 ? 170 ASP D C   1 
ATOM   10943 O O   . ASP D 1 170 ? 111.718 120.393 145.030 1.00 61.77 ? 170 ASP D O   1 
ATOM   10944 C CB  . ASP D 1 170 ? 113.138 117.267 145.389 1.00 61.77 ? 170 ASP D CB  1 
ATOM   10945 C CG  . ASP D 1 170 ? 112.546 117.211 146.775 1.00 61.77 ? 170 ASP D CG  1 
ATOM   10946 O OD1 . ASP D 1 170 ? 112.652 118.229 147.484 1.00 61.77 ? 170 ASP D OD1 1 
ATOM   10947 O OD2 . ASP D 1 170 ? 111.970 116.170 147.151 1.00 61.77 ? 170 ASP D OD2 1 
ATOM   10948 N N   . GLY D 1 171 ? 111.552 118.823 143.441 1.00 59.34 ? 171 GLY D N   1 
ATOM   10949 C CA  . GLY D 1 171 ? 110.314 119.328 142.908 1.00 59.34 ? 171 GLY D CA  1 
ATOM   10950 C C   . GLY D 1 171 ? 109.190 119.376 143.918 1.00 59.34 ? 171 GLY D C   1 
ATOM   10951 O O   . GLY D 1 171 ? 108.584 120.428 144.140 1.00 59.34 ? 171 GLY D O   1 
ATOM   10952 N N   . PRO D 1 172 ? 108.875 118.238 144.546 1.00 60.05 ? 172 PRO D N   1 
ATOM   10953 C CA  . PRO D 1 172 ? 107.714 118.219 145.449 1.00 60.05 ? 172 PRO D CA  1 
ATOM   10954 C C   . PRO D 1 172 ? 107.865 119.117 146.661 1.00 60.05 ? 172 PRO D C   1 
ATOM   10955 O O   . PRO D 1 172 ? 106.908 119.804 147.035 1.00 60.05 ? 172 PRO D O   1 
ATOM   10956 C CB  . PRO D 1 172 ? 107.611 116.741 145.840 1.00 60.05 ? 172 PRO D CB  1 
ATOM   10957 C CG  . PRO D 1 172 ? 108.250 116.024 144.727 1.00 60.05 ? 172 PRO D CG  1 
ATOM   10958 C CD  . PRO D 1 172 ? 109.394 116.881 144.318 1.00 60.05 ? 172 PRO D CD  1 
ATOM   10959 N N   . GLU D 1 173 ? 109.036 119.132 147.294 1.00 62.46 ? 173 GLU D N   1 
ATOM   10960 C CA  . GLU D 1 173 ? 109.233 120.005 148.443 1.00 62.46 ? 173 GLU D CA  1 
ATOM   10961 C C   . GLU D 1 173 ? 109.062 121.464 148.058 1.00 62.46 ? 173 GLU D C   1 
ATOM   10962 O O   . GLU D 1 173 ? 108.423 122.234 148.781 1.00 62.46 ? 173 GLU D O   1 
ATOM   10963 C CB  . GLU D 1 173 ? 110.615 119.771 149.038 1.00 62.46 ? 173 GLU D CB  1 
ATOM   10964 C CG  . GLU D 1 173 ? 110.942 120.619 150.235 1.00 62.46 ? 173 GLU D CG  1 
ATOM   10965 C CD  . GLU D 1 173 ? 112.271 120.236 150.836 1.00 62.46 ? 173 GLU D CD  1 
ATOM   10966 O OE1 . GLU D 1 173 ? 113.050 119.547 150.146 1.00 62.46 ? 173 GLU D OE1 1 
ATOM   10967 O OE2 . GLU D 1 173 ? 112.537 120.615 151.994 1.00 62.46 ? 173 GLU D OE2 1 
ATOM   10968 N N   . ALA D 1 174 ? 109.626 121.861 146.917 1.00 59.33 ? 174 ALA D N   1 
ATOM   10969 C CA  . ALA D 1 174 ? 109.469 123.233 146.460 1.00 59.33 ? 174 ALA D CA  1 
ATOM   10970 C C   . ALA D 1 174 ? 108.022 123.548 146.129 1.00 59.33 ? 174 ALA D C   1 
ATOM   10971 O O   . ALA D 1 174 ? 107.577 124.682 146.319 1.00 59.33 ? 174 ALA D O   1 
ATOM   10972 C CB  . ALA D 1 174 ? 110.354 123.487 145.245 1.00 59.33 ? 174 ALA D CB  1 
ATOM   10973 N N   . ARG D 1 175 ? 107.270 122.566 145.641 1.00 58.44 ? 175 ARG D N   1 
ATOM   10974 C CA  . ARG D 1 175 ? 105.884 122.834 145.291 1.00 58.44 ? 175 ARG D CA  1 
ATOM   10975 C C   . ARG D 1 175 ? 104.988 122.915 146.517 1.00 58.44 ? 175 ARG D C   1 
ATOM   10976 O O   . ARG D 1 175 ? 104.010 123.670 146.508 1.00 58.44 ? 175 ARG D O   1 
ATOM   10977 C CB  . ARG D 1 175 ? 105.368 121.769 144.330 1.00 58.44 ? 175 ARG D CB  1 
ATOM   10978 C CG  . ARG D 1 175 ? 105.927 121.897 142.931 1.00 58.44 ? 175 ARG D CG  1 
ATOM   10979 C CD  . ARG D 1 175 ? 105.043 121.216 141.906 1.00 58.44 ? 175 ARG D CD  1 
ATOM   10980 N NE  . ARG D 1 175 ? 105.058 119.765 142.041 1.00 58.44 ? 175 ARG D NE  1 
ATOM   10981 C CZ  . ARG D 1 175 ? 106.066 118.983 141.667 1.00 58.44 ? 175 ARG D CZ  1 
ATOM   10982 N NH1 . ARG D 1 175 ? 107.158 119.506 141.133 1.00 58.44 ? 175 ARG D NH1 1 
ATOM   10983 N NH2 . ARG D 1 175 ? 105.979 117.673 141.831 1.00 58.44 ? 175 ARG D NH2 1 
ATOM   10984 N N   . ARG D 1 176 ? 105.290 122.159 147.574 1.00 63.75 ? 176 ARG D N   1 
ATOM   10985 C CA  . ARG D 1 176 ? 104.468 122.236 148.779 1.00 63.75 ? 176 ARG D CA  1 
ATOM   10986 C C   . ARG D 1 176 ? 104.623 123.585 149.463 1.00 63.75 ? 176 ARG D C   1 
ATOM   10987 O O   . ARG D 1 176 ? 103.649 124.145 149.977 1.00 63.75 ? 176 ARG D O   1 
ATOM   10988 C CB  . ARG D 1 176 ? 104.829 121.113 149.749 1.00 63.75 ? 176 ARG D CB  1 
ATOM   10989 C CG  . ARG D 1 176 ? 104.594 119.715 149.213 1.00 63.75 ? 176 ARG D CG  1 
ATOM   10990 C CD  . ARG D 1 176 ? 104.791 118.656 150.282 1.00 63.75 ? 176 ARG D CD  1 
ATOM   10991 N NE  . ARG D 1 176 ? 105.963 118.906 151.114 1.00 63.75 ? 176 ARG D NE  1 
ATOM   10992 C CZ  . ARG D 1 176 ? 107.127 118.277 150.986 1.00 63.75 ? 176 ARG D CZ  1 
ATOM   10993 N NH1 . ARG D 1 176 ? 107.286 117.354 150.053 1.00 63.75 ? 176 ARG D NH1 1 
ATOM   10994 N NH2 . ARG D 1 176 ? 108.134 118.572 151.794 1.00 63.75 ? 176 ARG D NH2 1 
ATOM   10995 N N   . GLN D 1 177 ? 105.835 124.120 149.475 1.00 64.61 ? 177 GLN D N   1 
ATOM   10996 C CA  . GLN D 1 177 ? 106.168 125.349 150.180 1.00 64.61 ? 177 GLN D CA  1 
ATOM   10997 C C   . GLN D 1 177 ? 106.341 126.523 149.223 1.00 64.61 ? 177 GLN D C   1 
ATOM   10998 O O   . GLN D 1 177 ? 107.257 127.330 149.374 1.00 64.61 ? 177 GLN D O   1 
ATOM   10999 C CB  . GLN D 1 177 ? 107.424 125.154 151.021 1.00 64.61 ? 177 GLN D CB  1 
ATOM   11000 C CG  . GLN D 1 177 ? 107.179 124.376 152.298 1.00 64.61 ? 177 GLN D CG  1 
ATOM   11001 C CD  . GLN D 1 177 ? 108.436 123.747 152.848 1.00 64.61 ? 177 GLN D CD  1 
ATOM   11002 O OE1 . GLN D 1 177 ? 109.450 123.666 152.162 1.00 64.61 ? 177 GLN D OE1 1 
ATOM   11003 N NE2 . GLN D 1 177 ? 108.375 123.290 154.090 1.00 64.61 ? 177 GLN D NE2 1 
ATOM   11004 N N   . TRP D 1 178 ? 105.481 126.620 148.207 1.00 63.13 ? 178 TRP D N   1 
ATOM   11005 C CA  . TRP D 1 178 ? 105.656 127.677 147.217 1.00 63.13 ? 178 TRP D CA  1 
ATOM   11006 C C   . TRP D 1 178 ? 105.417 129.055 147.806 1.00 63.13 ? 178 TRP D C   1 
ATOM   11007 O O   . TRP D 1 178 ? 106.002 130.038 147.337 1.00 63.13 ? 178 TRP D O   1 
ATOM   11008 C CB  . TRP D 1 178 ? 104.728 127.473 146.030 1.00 63.13 ? 178 TRP D CB  1 
ATOM   11009 C CG  . TRP D 1 178 ? 105.110 128.364 144.913 1.00 63.13 ? 178 TRP D CG  1 
ATOM   11010 C CD1 . TRP D 1 178 ? 104.406 129.419 144.429 1.00 63.13 ? 178 TRP D CD1 1 
ATOM   11011 C CD2 . TRP D 1 178 ? 106.317 128.301 144.153 1.00 63.13 ? 178 TRP D CD2 1 
ATOM   11012 N NE1 . TRP D 1 178 ? 105.092 130.008 143.399 1.00 63.13 ? 178 TRP D NE1 1 
ATOM   11013 C CE2 . TRP D 1 178 ? 106.270 129.337 143.210 1.00 63.13 ? 178 TRP D CE2 1 
ATOM   11014 C CE3 . TRP D 1 178 ? 107.428 127.460 144.172 1.00 63.13 ? 178 TRP D CE3 1 
ATOM   11015 C CZ2 . TRP D 1 178 ? 107.292 129.556 142.296 1.00 63.13 ? 178 TRP D CZ2 1 
ATOM   11016 C CZ3 . TRP D 1 178 ? 108.437 127.679 143.265 1.00 63.13 ? 178 TRP D CZ3 1 
ATOM   11017 C CH2 . TRP D 1 178 ? 108.362 128.714 142.340 1.00 63.13 ? 178 TRP D CH2 1 
ATOM   11018 N N   . ASP D 1 179 ? 104.550 129.151 148.809 1.00 66.88 ? 179 ASP D N   1 
ATOM   11019 C CA  . ASP D 1 179 ? 104.328 130.422 149.479 1.00 66.88 ? 179 ASP D CA  1 
ATOM   11020 C C   . ASP D 1 179 ? 105.624 131.014 150.010 1.00 66.88 ? 179 ASP D C   1 
ATOM   11021 O O   . ASP D 1 179 ? 105.753 132.237 150.111 1.00 66.88 ? 179 ASP D O   1 
ATOM   11022 C CB  . ASP D 1 179 ? 103.333 130.216 150.611 1.00 66.88 ? 179 ASP D CB  1 
ATOM   11023 C CG  . ASP D 1 179 ? 103.780 129.137 151.584 1.00 66.88 ? 179 ASP D CG  1 
ATOM   11024 O OD1 . ASP D 1 179 ? 104.852 128.538 151.362 1.00 66.88 ? 179 ASP D OD1 1 
ATOM   11025 O OD2 . ASP D 1 179 ? 103.051 128.877 152.562 1.00 66.88 ? 179 ASP D OD2 1 
ATOM   11026 N N   . SER D 1 180 ? 106.600 130.168 150.333 1.00 63.56 ? 180 SER D N   1 
ATOM   11027 C CA  . SER D 1 180 ? 107.802 130.642 151.006 1.00 63.56 ? 180 SER D CA  1 
ATOM   11028 C C   . SER D 1 180 ? 108.781 131.285 150.036 1.00 63.56 ? 180 SER D C   1 
ATOM   11029 O O   . SER D 1 180 ? 109.386 132.313 150.353 1.00 63.56 ? 180 SER D O   1 
ATOM   11030 C CB  . SER D 1 180 ? 108.467 129.485 151.745 1.00 63.56 ? 180 SER D CB  1 
ATOM   11031 O OG  . SER D 1 180 ? 109.822 129.768 152.012 1.00 63.56 ? 180 SER D OG  1 
ATOM   11032 N N   . ILE D 1 181 ? 108.957 130.703 148.855 1.00 64.97 ? 181 ILE D N   1 
ATOM   11033 C CA  . ILE D 1 181 ? 110.032 131.098 147.955 1.00 64.97 ? 181 ILE D CA  1 
ATOM   11034 C C   . ILE D 1 181 ? 109.516 131.816 146.720 1.00 64.97 ? 181 ILE D C   1 
ATOM   11035 O O   . ILE D 1 181 ? 110.291 132.087 145.800 1.00 64.97 ? 181 ILE D O   1 
ATOM   11036 C CB  . ILE D 1 181 ? 110.885 129.891 147.554 1.00 64.97 ? 181 ILE D CB  1 
ATOM   11037 C CG1 . ILE D 1 181 ? 109.991 128.787 146.994 1.00 64.97 ? 181 ILE D CG1 1 
ATOM   11038 C CG2 . ILE D 1 181 ? 111.662 129.389 148.737 1.00 64.97 ? 181 ILE D CG2 1 
ATOM   11039 C CD1 . ILE D 1 181 ? 110.752 127.640 146.391 1.00 64.97 ? 181 ILE D CD1 1 
ATOM   11040 N N   . ALA D 1 182 ? 108.225 132.135 146.672 1.00 66.25 ? 182 ALA D N   1 
ATOM   11041 C CA  . ALA D 1 182 ? 107.684 132.782 145.484 1.00 66.25 ? 182 ALA D CA  1 
ATOM   11042 C C   . ALA D 1 182 ? 108.259 134.179 145.303 1.00 66.25 ? 182 ALA D C   1 
ATOM   11043 O O   . ALA D 1 182 ? 108.473 134.625 144.172 1.00 66.25 ? 182 ALA D O   1 
ATOM   11044 C CB  . ALA D 1 182 ? 106.161 132.832 145.562 1.00 66.25 ? 182 ALA D CB  1 
ATOM   11045 N N   . HIS D 1 183 ? 108.524 134.884 146.403 1.00 66.66 ? 183 HIS D N   1 
ATOM   11046 C CA  . HIS D 1 183 ? 109.043 136.241 146.306 1.00 66.66 ? 183 HIS D CA  1 
ATOM   11047 C C   . HIS D 1 183 ? 110.457 136.292 145.745 1.00 66.66 ? 183 HIS D C   1 
ATOM   11048 O O   . HIS D 1 183 ? 110.912 137.370 145.354 1.00 66.66 ? 183 HIS D O   1 
ATOM   11049 C CB  . HIS D 1 183 ? 109.026 136.908 147.673 1.00 66.66 ? 183 HIS D CB  1 
ATOM   11050 C CG  . HIS D 1 183 ? 110.107 136.422 148.579 1.00 66.66 ? 183 HIS D CG  1 
ATOM   11051 N ND1 . HIS D 1 183 ? 109.925 135.377 149.456 1.00 66.66 ? 183 HIS D ND1 1 
ATOM   11052 C CD2 . HIS D 1 183 ? 111.390 136.820 148.728 1.00 66.66 ? 183 HIS D CD2 1 
ATOM   11053 C CE1 . HIS D 1 183 ? 111.047 135.159 150.115 1.00 66.66 ? 183 HIS D CE1 1 
ATOM   11054 N NE2 . HIS D 1 183 ? 111.953 136.019 149.690 1.00 66.66 ? 183 HIS D NE2 1 
ATOM   11055 N N   . ILE D 1 184 ? 111.174 135.169 145.717 1.00 62.48 ? 184 ILE D N   1 
ATOM   11056 C CA  . ILE D 1 184 ? 112.528 135.180 145.185 1.00 62.48 ? 184 ILE D CA  1 
ATOM   11057 C C   . ILE D 1 184 ? 112.478 135.424 143.687 1.00 62.48 ? 184 ILE D C   1 
ATOM   11058 O O   . ILE D 1 184 ? 111.604 134.902 142.982 1.00 62.48 ? 184 ILE D O   1 
ATOM   11059 C CB  . ILE D 1 184 ? 113.254 133.866 145.507 1.00 62.48 ? 184 ILE D CB  1 
ATOM   11060 C CG1 . ILE D 1 184 ? 113.372 133.694 147.015 1.00 62.48 ? 184 ILE D CG1 1 
ATOM   11061 C CG2 . ILE D 1 184 ? 114.633 133.849 144.890 1.00 62.48 ? 184 ILE D CG2 1 
ATOM   11062 C CD1 . ILE D 1 184 ? 114.225 132.525 147.412 1.00 62.48 ? 184 ILE D CD1 1 
ATOM   11063 N N   . TYR D 1 185 ? 113.411 136.235 143.193 1.00 58.94 ? 185 TYR D N   1 
ATOM   11064 C CA  . TYR D 1 185 ? 113.443 136.535 141.769 1.00 58.94 ? 185 TYR D CA  1 
ATOM   11065 C C   . TYR D 1 185 ? 114.109 135.417 140.980 1.00 58.94 ? 185 TYR D C   1 
ATOM   11066 O O   . TYR D 1 185 ? 113.531 134.893 140.023 1.00 58.94 ? 185 TYR D O   1 
ATOM   11067 C CB  . TYR D 1 185 ? 114.164 137.854 141.522 1.00 58.94 ? 185 TYR D CB  1 
ATOM   11068 C CG  . TYR D 1 185 ? 114.107 138.270 140.079 1.00 58.94 ? 185 TYR D CG  1 
ATOM   11069 C CD1 . TYR D 1 185 ? 112.890 138.489 139.456 1.00 58.94 ? 185 TYR D CD1 1 
ATOM   11070 C CD2 . TYR D 1 185 ? 115.263 138.427 139.334 1.00 58.94 ? 185 TYR D CD2 1 
ATOM   11071 C CE1 . TYR D 1 185 ? 112.825 138.859 138.139 1.00 58.94 ? 185 TYR D CE1 1 
ATOM   11072 C CE2 . TYR D 1 185 ? 115.208 138.797 138.016 1.00 58.94 ? 185 TYR D CE2 1 
ATOM   11073 C CZ  . TYR D 1 185 ? 113.987 139.013 137.422 1.00 58.94 ? 185 TYR D CZ  1 
ATOM   11074 O OH  . TYR D 1 185 ? 113.924 139.386 136.102 1.00 58.94 ? 185 TYR D OH  1 
ATOM   11075 N N   . HIS D 1 186 ? 115.319 135.039 141.363 1.00 57.77 ? 186 HIS D N   1 
ATOM   11076 C CA  . HIS D 1 186 ? 116.058 133.989 140.680 1.00 57.77 ? 186 HIS D CA  1 
ATOM   11077 C C   . HIS D 1 186 ? 115.979 132.718 141.514 1.00 57.77 ? 186 HIS D C   1 
ATOM   11078 O O   . HIS D 1 186 ? 116.629 132.612 142.558 1.00 57.77 ? 186 HIS D O   1 
ATOM   11079 C CB  . HIS D 1 186 ? 117.502 134.412 140.454 1.00 57.77 ? 186 HIS D CB  1 
ATOM   11080 C CG  . HIS D 1 186 ? 118.216 133.579 139.444 1.00 57.77 ? 186 HIS D CG  1 
ATOM   11081 N ND1 . HIS D 1 186 ? 119.589 133.502 139.381 1.00 57.77 ? 186 HIS D ND1 1 
ATOM   11082 C CD2 . HIS D 1 186 ? 117.748 132.784 138.456 1.00 57.77 ? 186 HIS D CD2 1 
ATOM   11083 C CE1 . HIS D 1 186 ? 119.936 132.697 138.395 1.00 57.77 ? 186 HIS D CE1 1 
ATOM   11084 N NE2 . HIS D 1 186 ? 118.838 132.248 137.818 1.00 57.77 ? 186 HIS D NE2 1 
ATOM   11085 N N   . LYS D 1 187 ? 115.183 131.755 141.056 1.00 56.76 ? 187 LYS D N   1 
ATOM   11086 C CA  . LYS D 1 187 ? 115.022 130.483 141.756 1.00 56.76 ? 187 LYS D CA  1 
ATOM   11087 C C   . LYS D 1 187 ? 115.989 129.439 141.200 1.00 56.76 ? 187 LYS D C   1 
ATOM   11088 O O   . LYS D 1 187 ? 115.609 128.365 140.747 1.00 56.76 ? 187 LYS D O   1 
ATOM   11089 C CB  . LYS D 1 187 ? 113.580 130.010 141.658 1.00 56.76 ? 187 LYS D CB  1 
ATOM   11090 C CG  . LYS D 1 187 ? 112.590 131.104 141.918 1.00 56.76 ? 187 LYS D CG  1 
ATOM   11091 C CD  . LYS D 1 187 ? 111.184 130.582 141.933 1.00 56.76 ? 187 LYS D CD  1 
ATOM   11092 C CE  . LYS D 1 187 ? 110.193 131.687 142.269 1.00 56.76 ? 187 LYS D CE  1 
ATOM   11093 N NZ  . LYS D 1 187 ? 109.664 132.377 141.060 1.00 56.76 ? 187 LYS D NZ  1 
ATOM   11094 N N   . CYS D 1 188 ? 117.267 129.781 141.251 1.00 54.40 ? 188 CYS D N   1 
ATOM   11095 C CA  . CYS D 1 188 ? 118.326 128.900 140.792 1.00 54.40 ? 188 CYS D CA  1 
ATOM   11096 C C   . CYS D 1 188 ? 118.756 127.984 141.926 1.00 54.40 ? 188 CYS D C   1 
ATOM   11097 O O   . CYS D 1 188 ? 118.999 128.445 143.042 1.00 54.40 ? 188 CYS D O   1 
ATOM   11098 C CB  . CYS D 1 188 ? 119.511 129.720 140.296 1.00 54.40 ? 188 CYS D CB  1 
ATOM   11099 S SG  . CYS D 1 188 ? 120.973 128.763 139.963 1.00 54.40 ? 188 CYS D SG  1 
ATOM   11100 N N   . HIS D 1 189 ? 118.847 126.689 141.643 1.00 52.49 ? 189 HIS D N   1 
ATOM   11101 C CA  . HIS D 1 189 ? 119.221 125.716 142.657 1.00 52.49 ? 189 HIS D CA  1 
ATOM   11102 C C   . HIS D 1 189 ? 120.318 124.760 142.233 1.00 52.49 ? 189 HIS D C   1 
ATOM   11103 O O   . HIS D 1 189 ? 120.895 124.099 143.101 1.00 52.49 ? 189 HIS D O   1 
ATOM   11104 C CB  . HIS D 1 189 ? 117.999 124.895 143.098 1.00 52.49 ? 189 HIS D CB  1 
ATOM   11105 C CG  . HIS D 1 189 ? 117.212 124.311 141.968 1.00 52.49 ? 189 HIS D CG  1 
ATOM   11106 N ND1 . HIS D 1 189 ? 117.729 123.368 141.108 1.00 52.49 ? 189 HIS D ND1 1 
ATOM   11107 C CD2 . HIS D 1 189 ? 115.938 124.524 141.568 1.00 52.49 ? 189 HIS D CD2 1 
ATOM   11108 C CE1 . HIS D 1 189 ? 116.810 123.030 140.223 1.00 52.49 ? 189 HIS D CE1 1 
ATOM   11109 N NE2 . HIS D 1 189 ? 115.714 123.718 140.479 1.00 52.49 ? 189 HIS D NE2 1 
ATOM   11110 N N   . THR D 1 190 ? 120.628 124.658 140.947 1.00 50.62 ? 190 THR D N   1 
ATOM   11111 C CA  . THR D 1 190 ? 121.641 123.726 140.472 1.00 50.62 ? 190 THR D CA  1 
ATOM   11112 C C   . THR D 1 190 ? 122.313 124.361 139.271 1.00 50.62 ? 190 THR D C   1 
ATOM   11113 O O   . THR D 1 190 ? 121.634 124.706 138.303 1.00 50.62 ? 190 THR D O   1 
ATOM   11114 C CB  . THR D 1 190 ? 121.018 122.390 140.078 1.00 50.62 ? 190 THR D CB  1 
ATOM   11115 O OG1 . THR D 1 190 ? 120.233 121.880 141.159 1.00 50.62 ? 190 THR D OG1 1 
ATOM   11116 C CG2 . THR D 1 190 ? 122.104 121.390 139.751 1.00 50.62 ? 190 THR D CG2 1 
ATOM   11117 N N   . VAL D 1 191 ? 123.629 124.521 139.323 1.00 47.24 ? 191 VAL D N   1 
ATOM   11118 C CA  . VAL D 1 191 ? 124.371 125.103 138.212 1.00 47.24 ? 191 VAL D CA  1 
ATOM   11119 C C   . VAL D 1 191 ? 125.430 124.103 137.784 1.00 47.24 ? 191 VAL D C   1 
ATOM   11120 O O   . VAL D 1 191 ? 126.164 123.583 138.628 1.00 47.24 ? 191 VAL D O   1 
ATOM   11121 C CB  . VAL D 1 191 ? 125.013 126.443 138.600 1.00 47.24 ? 191 VAL D CB  1 
ATOM   11122 C CG1 . VAL D 1 191 ? 125.698 127.051 137.417 1.00 47.24 ? 191 VAL D CG1 1 
ATOM   11123 C CG2 . VAL D 1 191 ? 123.984 127.372 139.144 1.00 47.24 ? 191 VAL D CG2 1 
ATOM   11124 N N   . THR D 1 192 ? 125.514 123.828 136.485 1.00 44.10 ? 192 THR D N   1 
ATOM   11125 C CA  . THR D 1 192 ? 126.396 122.787 135.983 1.00 44.10 ? 192 THR D CA  1 
ATOM   11126 C C   . THR D 1 192 ? 127.459 123.396 135.090 1.00 44.10 ? 192 THR D C   1 
ATOM   11127 O O   . THR D 1 192 ? 127.146 124.107 134.133 1.00 44.10 ? 192 THR D O   1 
ATOM   11128 C CB  . THR D 1 192 ? 125.622 121.730 135.203 1.00 44.10 ? 192 THR D CB  1 
ATOM   11129 O OG1 . THR D 1 192 ? 124.849 122.367 134.183 1.00 44.10 ? 192 THR D OG1 1 
ATOM   11130 C CG2 . THR D 1 192 ? 124.695 120.955 136.119 1.00 44.10 ? 192 THR D CG2 1 
ATOM   11131 N N   . ALA D 1 193 ? 128.707 123.100 135.399 1.00 45.10 ? 193 ALA D N   1 
ATOM   11132 C CA  . ALA D 1 193 ? 129.833 123.531 134.593 1.00 45.10 ? 193 ALA D CA  1 
ATOM   11133 C C   . ALA D 1 193 ? 130.489 122.319 133.954 1.00 45.10 ? 193 ALA D C   1 
ATOM   11134 O O   . ALA D 1 193 ? 130.712 121.306 134.616 1.00 45.10 ? 193 ALA D O   1 
ATOM   11135 C CB  . ALA D 1 193 ? 130.849 124.300 135.431 1.00 45.10 ? 193 ALA D CB  1 
ATOM   11136 N N   . LEU D 1 194 ? 130.790 122.427 132.672 1.00 42.67 ? 194 LEU D N   1 
ATOM   11137 C CA  . LEU D 1 194 ? 131.443 121.374 131.918 1.00 42.67 ? 194 LEU D CA  1 
ATOM   11138 C C   . LEU D 1 194 ? 132.891 121.770 131.712 1.00 42.67 ? 194 LEU D C   1 
ATOM   11139 O O   . LEU D 1 194 ? 133.173 122.864 131.215 1.00 42.67 ? 194 LEU D O   1 
ATOM   11140 C CB  . LEU D 1 194 ? 130.766 121.169 130.566 1.00 42.67 ? 194 LEU D CB  1 
ATOM   11141 C CG  . LEU D 1 194 ? 129.470 120.377 130.458 1.00 42.67 ? 194 LEU D CG  1 
ATOM   11142 C CD1 . LEU D 1 194 ? 129.734 118.958 130.851 1.00 42.67 ? 194 LEU D CD1 1 
ATOM   11143 C CD2 . LEU D 1 194 ? 128.365 120.977 131.304 1.00 42.67 ? 194 LEU D CD2 1 
ATOM   11144 N N   . ASP D 1 195 ? 133.802 120.900 132.114 1.00 47.69 ? 195 ASP D N   1 
ATOM   11145 C CA  . ASP D 1 195 ? 135.209 121.047 131.770 1.00 47.69 ? 195 ASP D CA  1 
ATOM   11146 C C   . ASP D 1 195 ? 135.406 120.230 130.510 1.00 47.69 ? 195 ASP D C   1 
ATOM   11147 O O   . ASP D 1 195 ? 135.439 119.000 130.568 1.00 47.69 ? 195 ASP D O   1 
ATOM   11148 C CB  . ASP D 1 195 ? 136.104 120.547 132.896 1.00 47.69 ? 195 ASP D CB  1 
ATOM   11149 C CG  . ASP D 1 195 ? 135.965 121.363 134.159 1.00 47.69 ? 195 ASP D CG  1 
ATOM   11150 O OD1 . ASP D 1 195 ? 135.667 122.572 134.072 1.00 47.69 ? 195 ASP D OD1 1 
ATOM   11151 O OD2 . ASP D 1 195 ? 136.156 120.791 135.251 1.00 47.69 ? 195 ASP D OD2 1 
ATOM   11152 N N   . MET D 1 196 ? 135.484 120.894 129.356 1.00 46.47 ? 196 MET D N   1 
ATOM   11153 C CA  . MET D 1 196 ? 135.572 120.162 128.096 1.00 46.47 ? 196 MET D CA  1 
ATOM   11154 C C   . MET D 1 196 ? 137.037 119.801 127.884 1.00 46.47 ? 196 MET D C   1 
ATOM   11155 O O   . MET D 1 196 ? 137.771 120.460 127.147 1.00 46.47 ? 196 MET D O   1 
ATOM   11156 C CB  . MET D 1 196 ? 135.028 120.989 126.941 1.00 46.47 ? 196 MET D CB  1 
ATOM   11157 C CG  . MET D 1 196 ? 133.549 121.245 126.963 1.00 46.47 ? 196 MET D CG  1 
ATOM   11158 S SD  . MET D 1 196 ? 132.616 119.725 126.960 1.00 46.47 ? 196 MET D SD  1 
ATOM   11159 C CE  . MET D 1 196 ? 131.004 120.339 126.511 1.00 46.47 ? 196 MET D CE  1 
ATOM   11160 N N   . GLN D 1 197 ? 137.470 118.747 128.567 1.00 45.72 ? 197 GLN D N   1 
ATOM   11161 C CA  . GLN D 1 197 ? 138.873 118.371 128.524 1.00 45.72 ? 197 GLN D CA  1 
ATOM   11162 C C   . GLN D 1 197 ? 139.348 118.209 127.092 1.00 45.72 ? 197 GLN D C   1 
ATOM   11163 O O   . GLN D 1 197 ? 138.588 117.807 126.210 1.00 45.72 ? 197 GLN D O   1 
ATOM   11164 C CB  . GLN D 1 197 ? 139.114 117.078 129.292 1.00 45.72 ? 197 GLN D CB  1 
ATOM   11165 C CG  . GLN D 1 197 ? 139.622 117.271 130.698 1.00 45.72 ? 197 GLN D CG  1 
ATOM   11166 C CD  . GLN D 1 197 ? 138.527 117.585 131.680 1.00 45.72 ? 197 GLN D CD  1 
ATOM   11167 O OE1 . GLN D 1 197 ? 137.354 117.367 131.407 1.00 45.72 ? 197 GLN D OE1 1 
ATOM   11168 N NE2 . GLN D 1 197 ? 138.905 118.102 132.839 1.00 45.72 ? 197 GLN D NE2 1 
ATOM   11169 N N   . ARG D 1 198 ? 140.615 118.555 126.864 1.00 50.21 ? 198 ARG D N   1 
ATOM   11170 C CA  . ARG D 1 198 ? 141.237 118.335 125.569 1.00 50.21 ? 198 ARG D CA  1 
ATOM   11171 C C   . ARG D 1 198 ? 141.360 116.854 125.256 1.00 50.21 ? 198 ARG D C   1 
ATOM   11172 O O   . ARG D 1 198 ? 141.622 116.490 124.105 1.00 50.21 ? 198 ARG D O   1 
ATOM   11173 C CB  . ARG D 1 198 ? 142.614 118.996 125.529 1.00 50.21 ? 198 ARG D CB  1 
ATOM   11174 C CG  . ARG D 1 198 ? 143.202 119.087 124.147 1.00 50.21 ? 198 ARG D CG  1 
ATOM   11175 C CD  . ARG D 1 198 ? 144.546 119.755 124.144 1.00 50.21 ? 198 ARG D CD  1 
ATOM   11176 N NE  . ARG D 1 198 ? 144.502 121.050 124.804 1.00 50.21 ? 198 ARG D NE  1 
ATOM   11177 C CZ  . ARG D 1 198 ? 145.509 121.912 124.809 1.00 50.21 ? 198 ARG D CZ  1 
ATOM   11178 N NH1 . ARG D 1 198 ? 146.623 121.629 124.152 1.00 50.21 ? 198 ARG D NH1 1 
ATOM   11179 N NH2 . ARG D 1 198 ? 145.392 123.068 125.443 1.00 50.21 ? 198 ARG D NH2 1 
ATOM   11180 N N   . SER D 1 199 ? 141.171 115.991 126.254 1.00 50.19 ? 199 SER D N   1 
ATOM   11181 C CA  . SER D 1 199 ? 141.160 114.550 126.054 1.00 50.19 ? 199 SER D CA  1 
ATOM   11182 C C   . SER D 1 199 ? 139.761 114.008 125.794 1.00 50.19 ? 199 SER D C   1 
ATOM   11183 O O   . SER D 1 199 ? 139.490 112.838 126.084 1.00 50.19 ? 199 SER D O   1 
ATOM   11184 C CB  . SER D 1 199 ? 141.788 113.860 127.261 1.00 50.19 ? 199 SER D CB  1 
ATOM   11185 O OG  . SER D 1 199 ? 143.131 114.277 127.423 1.00 50.19 ? 199 SER D OG  1 
ATOM   11186 N N   . ALA D 1 200 ? 138.862 114.847 125.283 1.00 44.33 ? 200 ALA D N   1 
ATOM   11187 C CA  . ALA D 1 200 ? 137.515 114.458 124.885 1.00 44.33 ? 200 ALA D CA  1 
ATOM   11188 C C   . ALA D 1 200 ? 136.686 113.959 126.058 1.00 44.33 ? 200 ALA D C   1 
ATOM   11189 O O   . ALA D 1 200 ? 135.527 113.571 125.880 1.00 44.33 ? 200 ALA D O   1 
ATOM   11190 C CB  . ALA D 1 200 ? 137.565 113.393 123.792 1.00 44.33 ? 200 ALA D CB  1 
ATOM   11191 N N   . ALA D 1 201 ? 137.252 113.988 127.256 1.00 46.09 ? 201 ALA D N   1 
ATOM   11192 C CA  . ALA D 1 201 ? 136.610 113.450 128.449 1.00 46.09 ? 201 ALA D CA  1 
ATOM   11193 C C   . ALA D 1 201 ? 136.049 114.602 129.273 1.00 46.09 ? 201 ALA D C   1 
ATOM   11194 O O   . ALA D 1 201 ? 136.665 115.043 130.241 1.00 46.09 ? 201 ALA D O   1 
ATOM   11195 C CB  . ALA D 1 201 ? 137.604 112.624 129.252 1.00 46.09 ? 201 ALA D CB  1 
ATOM   11196 N N   . CYS D 1 202 ? 134.864 115.071 128.903 1.00 46.47 ? 202 CYS D N   1 
ATOM   11197 C CA  . CYS D 1 202 ? 134.250 116.195 129.597 1.00 46.47 ? 202 CYS D CA  1 
ATOM   11198 C C   . CYS D 1 202 ? 133.900 115.818 131.030 1.00 46.47 ? 202 CYS D C   1 
ATOM   11199 O O   . CYS D 1 202 ? 133.475 114.695 131.304 1.00 46.47 ? 202 CYS D O   1 
ATOM   11200 C CB  . CYS D 1 202 ? 133.007 116.670 128.845 1.00 46.47 ? 202 CYS D CB  1 
ATOM   11201 S SG  . CYS D 1 202 ? 131.531 115.700 129.115 1.00 46.47 ? 202 CYS D SG  1 
ATOM   11202 N N   . THR D 1 203 ? 134.097 116.761 131.949 1.00 43.12 ? 203 THR D N   1 
ATOM   11203 C CA  . THR D 1 203 ? 133.889 116.517 133.372 1.00 43.12 ? 203 THR D CA  1 
ATOM   11204 C C   . THR D 1 203 ? 132.862 117.486 133.942 1.00 43.12 ? 203 THR D C   1 
ATOM   11205 O O   . THR D 1 203 ? 132.999 118.702 133.792 1.00 43.12 ? 203 THR D O   1 
ATOM   11206 C CB  . THR D 1 203 ? 135.203 116.630 134.137 1.00 43.12 ? 203 THR D CB  1 
ATOM   11207 O OG1 . THR D 1 203 ? 136.099 115.601 133.699 1.00 43.12 ? 203 THR D OG1 1 
ATOM   11208 C CG2 . THR D 1 203 ? 134.961 116.484 135.620 1.00 43.12 ? 203 THR D CG2 1 
ATOM   11209 N N   . LEU D 1 204 ? 131.855 116.943 134.616 1.00 41.59 ? 204 LEU D N   1 
ATOM   11210 C CA  . LEU D 1 204 ? 130.764 117.724 135.173 1.00 41.59 ? 204 LEU D CA  1 
ATOM   11211 C C   . LEU D 1 204 ? 131.117 118.280 136.552 1.00 41.59 ? 204 LEU D C   1 
ATOM   11212 O O   . LEU D 1 204 ? 131.854 117.666 137.326 1.00 41.59 ? 204 LEU D O   1 
ATOM   11213 C CB  . LEU D 1 204 ? 129.507 116.865 135.254 1.00 41.59 ? 204 LEU D CB  1 
ATOM   11214 C CG  . LEU D 1 204 ? 128.220 117.534 135.701 1.00 41.59 ? 204 LEU D CG  1 
ATOM   11215 C CD1 . LEU D 1 204 ? 128.021 118.788 134.918 1.00 41.59 ? 204 LEU D CD1 1 
ATOM   11216 C CD2 . LEU D 1 204 ? 127.059 116.612 135.479 1.00 41.59 ? 204 LEU D CD2 1 
ATOM   11217 N N   . LYS D 1 205 ? 130.590 119.469 136.842 1.00 45.81 ? 205 LYS D N   1 
ATOM   11218 C CA  . LYS D 1 205 ? 130.737 120.131 138.126 1.00 45.81 ? 205 LYS D CA  1 
ATOM   11219 C C   . LYS D 1 205 ? 129.387 120.689 138.521 1.00 45.81 ? 205 LYS D C   1 
ATOM   11220 O O   . LYS D 1 205 ? 128.694 121.265 137.684 1.00 45.81 ? 205 LYS D O   1 
ATOM   11221 C CB  . LYS D 1 205 ? 131.735 121.274 138.057 1.00 45.81 ? 205 LYS D CB  1 
ATOM   11222 C CG  . LYS D 1 205 ? 133.124 120.854 137.708 1.00 45.81 ? 205 LYS D CG  1 
ATOM   11223 C CD  . LYS D 1 205 ? 134.068 122.013 137.850 1.00 45.81 ? 205 LYS D CD  1 
ATOM   11224 C CE  . LYS D 1 205 ? 133.897 122.976 136.712 1.00 45.81 ? 205 LYS D CE  1 
ATOM   11225 N NZ  . LYS D 1 205 ? 134.889 124.073 136.792 1.00 45.81 ? 205 LYS D NZ  1 
ATOM   11226 N N   . THR D 1 206 ? 129.023 120.553 139.790 1.00 49.77 ? 206 THR D N   1 
ATOM   11227 C CA  . THR D 1 206 ? 127.706 120.966 140.237 1.00 49.77 ? 206 THR D CA  1 
ATOM   11228 C C   . THR D 1 206 ? 127.833 121.928 141.403 1.00 49.77 ? 206 THR D C   1 
ATOM   11229 O O   . THR D 1 206 ? 128.616 121.707 142.330 1.00 49.77 ? 206 THR D O   1 
ATOM   11230 C CB  . THR D 1 206 ? 126.854 119.764 140.651 1.00 49.77 ? 206 THR D CB  1 
ATOM   11231 O OG1 . THR D 1 206 ? 126.861 118.794 139.602 1.00 49.77 ? 206 THR D OG1 1 
ATOM   11232 C CG2 . THR D 1 206 ? 125.427 120.185 140.895 1.00 49.77 ? 206 THR D CG2 1 
ATOM   11233 N N   . ALA D 1 207 ? 127.046 122.992 141.353 1.00 51.44 ? 207 ALA D N   1 
ATOM   11234 C CA  . ALA D 1 207 ? 126.980 123.965 142.426 1.00 51.44 ? 207 ALA D CA  1 
ATOM   11235 C C   . ALA D 1 207 ? 125.555 124.062 142.936 1.00 51.44 ? 207 ALA D C   1 
ATOM   11236 O O   . ALA D 1 207 ? 124.602 124.077 142.147 1.00 51.44 ? 207 ALA D O   1 
ATOM   11237 C CB  . ALA D 1 207 ? 127.449 125.330 141.962 1.00 51.44 ? 207 ALA D CB  1 
ATOM   11238 N N   . PHE D 1 208 ? 125.429 124.140 144.257 1.00 52.38 ? 208 PHE D N   1 
ATOM   11239 C CA  . PHE D 1 208 ? 124.149 124.248 144.946 1.00 52.38 ? 208 PHE D CA  1 
ATOM   11240 C C   . PHE D 1 208 ? 124.084 125.572 145.693 1.00 52.38 ? 208 PHE D C   1 
ATOM   11241 O O   . PHE D 1 208 ? 124.876 125.789 146.634 1.00 52.38 ? 208 PHE D O   1 
ATOM   11242 C CB  . PHE D 1 208 ? 123.962 123.086 145.917 1.00 52.38 ? 208 PHE D CB  1 
ATOM   11243 C CG  . PHE D 1 208 ? 123.558 121.789 145.266 1.00 52.38 ? 208 PHE D CG  1 
ATOM   11244 C CD1 . PHE D 1 208 ? 122.412 121.704 144.502 1.00 52.38 ? 208 PHE D CD1 1 
ATOM   11245 C CD2 . PHE D 1 208 ? 124.310 120.647 145.451 1.00 52.38 ? 208 PHE D CD2 1 
ATOM   11246 C CE1 . PHE D 1 208 ? 122.044 120.509 143.919 1.00 52.38 ? 208 PHE D CE1 1 
ATOM   11247 C CE2 . PHE D 1 208 ? 123.943 119.457 144.868 1.00 52.38 ? 208 PHE D CE2 1 
ATOM   11248 C CZ  . PHE D 1 208 ? 122.812 119.389 144.105 1.00 52.38 ? 208 PHE D CZ  1 
ATOM   11249 N N   . PRO D 1 209 ? 123.221 126.497 145.285 1.00 55.62 ? 209 PRO D N   1 
ATOM   11250 C CA  . PRO D 1 209 ? 122.890 127.637 146.122 1.00 55.62 ? 209 PRO D CA  1 
ATOM   11251 C C   . PRO D 1 209 ? 121.728 127.309 147.034 1.00 55.62 ? 209 PRO D C   1 
ATOM   11252 O O   . PRO D 1 209 ? 120.637 126.953 146.566 1.00 55.62 ? 209 PRO D O   1 
ATOM   11253 C CB  . PRO D 1 209 ? 122.504 128.725 145.108 1.00 55.62 ? 209 PRO D CB  1 
ATOM   11254 C CG  . PRO D 1 209 ? 122.754 128.148 143.770 1.00 55.62 ? 209 PRO D CG  1 
ATOM   11255 C CD  . PRO D 1 209 ? 122.697 126.681 143.929 1.00 55.62 ? 209 PRO D CD  1 
ATOM   11256 N N   . PRO D 1 210 ? 121.915 127.430 148.339 1.00 59.97 ? 210 PRO D N   1 
ATOM   11257 C CA  . PRO D 1 210 ? 120.891 126.994 149.289 1.00 59.97 ? 210 PRO D CA  1 
ATOM   11258 C C   . PRO D 1 210 ? 119.820 128.028 149.580 1.00 59.97 ? 210 PRO D C   1 
ATOM   11259 O O   . PRO D 1 210 ? 119.153 127.920 150.610 1.00 59.97 ? 210 PRO D O   1 
ATOM   11260 C CB  . PRO D 1 210 ? 121.706 126.699 150.551 1.00 59.97 ? 210 PRO D CB  1 
ATOM   11261 C CG  . PRO D 1 210 ? 123.114 126.662 150.114 1.00 59.97 ? 210 PRO D CG  1 
ATOM   11262 C CD  . PRO D 1 210 ? 123.209 127.612 148.994 1.00 59.97 ? 210 PRO D CD  1 
ATOM   11263 N N   . LEU D 1 211 ? 119.661 129.034 148.722 1.00 61.21 ? 211 LEU D N   1 
ATOM   11264 C CA  . LEU D 1 211 ? 118.766 130.140 149.047 1.00 61.21 ? 211 LEU D CA  1 
ATOM   11265 C C   . LEU D 1 211 ? 117.342 129.660 149.295 1.00 61.21 ? 211 LEU D C   1 
ATOM   11266 O O   . LEU D 1 211 ? 116.712 130.052 150.282 1.00 61.21 ? 211 LEU D O   1 
ATOM   11267 C CB  . LEU D 1 211 ? 118.793 131.185 147.939 1.00 61.21 ? 211 LEU D CB  1 
ATOM   11268 C CG  . LEU D 1 211 ? 118.020 132.438 148.330 1.00 61.21 ? 211 LEU D CG  1 
ATOM   11269 C CD1 . LEU D 1 211 ? 118.695 133.097 149.505 1.00 61.21 ? 211 LEU D CD1 1 
ATOM   11270 C CD2 . LEU D 1 211 ? 117.909 133.391 147.167 1.00 61.21 ? 211 LEU D CD2 1 
ATOM   11271 N N   . LEU D 1 212 ? 116.814 128.806 148.417 1.00 61.08 ? 212 LEU D N   1 
ATOM   11272 C CA  . LEU D 1 212 ? 115.474 128.277 148.640 1.00 61.08 ? 212 LEU D CA  1 
ATOM   11273 C C   . LEU D 1 212 ? 115.422 127.393 149.878 1.00 61.08 ? 212 LEU D C   1 
ATOM   11274 O O   . LEU D 1 212 ? 114.438 127.425 150.625 1.00 61.08 ? 212 LEU D O   1 
ATOM   11275 C CB  . LEU D 1 212 ? 115.005 127.490 147.423 1.00 61.08 ? 212 LEU D CB  1 
ATOM   11276 C CG  . LEU D 1 212 ? 115.096 128.163 146.061 1.00 61.08 ? 212 LEU D CG  1 
ATOM   11277 C CD1 . LEU D 1 212 ? 114.920 127.134 144.981 1.00 61.08 ? 212 LEU D CD1 1 
ATOM   11278 C CD2 . LEU D 1 212 ? 114.042 129.221 145.937 1.00 61.08 ? 212 LEU D CD2 1 
ATOM   11279 N N   . ARG D 1 213 ? 116.465 126.596 150.108 1.00 62.88 ? 213 ARG D N   1 
ATOM   11280 C CA  . ARG D 1 213 ? 116.521 125.776 151.313 1.00 62.88 ? 213 ARG D CA  1 
ATOM   11281 C C   . ARG D 1 213 ? 116.519 126.640 152.563 1.00 62.88 ? 213 ARG D C   1 
ATOM   11282 O O   . ARG D 1 213 ? 115.657 126.491 153.436 1.00 62.88 ? 213 ARG D O   1 
ATOM   11283 C CB  . ARG D 1 213 ? 117.767 124.899 151.290 1.00 62.88 ? 213 ARG D CB  1 
ATOM   11284 C CG  . ARG D 1 213 ? 118.040 124.213 152.598 1.00 62.88 ? 213 ARG D CG  1 
ATOM   11285 C CD  . ARG D 1 213 ? 116.960 123.210 152.899 1.00 62.88 ? 213 ARG D CD  1 
ATOM   11286 N NE  . ARG D 1 213 ? 117.075 122.029 152.055 1.00 62.88 ? 213 ARG D NE  1 
ATOM   11287 C CZ  . ARG D 1 213 ? 116.097 121.155 151.856 1.00 62.88 ? 213 ARG D CZ  1 
ATOM   11288 N NH1 . ARG D 1 213 ? 114.921 121.329 152.438 1.00 62.88 ? 213 ARG D NH1 1 
ATOM   11289 N NH2 . ARG D 1 213 ? 116.298 120.108 151.071 1.00 62.88 ? 213 ARG D NH2 1 
ATOM   11290 N N   . SER D 1 214 ? 117.492 127.543 152.669 1.00 64.00 ? 214 SER D N   1 
ATOM   11291 C CA  . SER D 1 214 ? 117.569 128.423 153.824 1.00 64.00 ? 214 SER D CA  1 
ATOM   11292 C C   . SER D 1 214 ? 116.319 129.269 153.962 1.00 64.00 ? 214 SER D C   1 
ATOM   11293 O O   . SER D 1 214 ? 116.016 129.771 155.048 1.00 64.00 ? 214 SER D O   1 
ATOM   11294 C CB  . SER D 1 214 ? 118.795 129.314 153.711 1.00 64.00 ? 214 SER D CB  1 
ATOM   11295 O OG  . SER D 1 214 ? 118.812 129.971 152.462 1.00 64.00 ? 214 SER D OG  1 
ATOM   11296 N N   . THR D 1 215 ? 115.581 129.449 152.873 1.00 62.04 ? 215 THR D N   1 
ATOM   11297 C CA  . THR D 1 215 ? 114.354 130.223 152.960 1.00 62.04 ? 215 THR D CA  1 
ATOM   11298 C C   . THR D 1 215 ? 113.236 129.406 153.586 1.00 62.04 ? 215 THR D C   1 
ATOM   11299 O O   . THR D 1 215 ? 112.653 129.811 154.597 1.00 62.04 ? 215 THR D O   1 
ATOM   11300 C CB  . THR D 1 215 ? 113.952 130.720 151.580 1.00 62.04 ? 215 THR D CB  1 
ATOM   11301 O OG1 . THR D 1 215 ? 114.891 131.706 151.147 1.00 62.04 ? 215 THR D OG1 1 
ATOM   11302 C CG2 . THR D 1 215 ? 112.582 131.342 151.631 1.00 62.04 ? 215 THR D CG2 1 
ATOM   11303 N N   . ILE D 1 216 ? 112.920 128.249 153.003 1.00 65.18 ? 216 ILE D N   1 
ATOM   11304 C CA  . ILE D 1 216 ? 111.811 127.453 153.522 1.00 65.18 ? 216 ILE D CA  1 
ATOM   11305 C C   . ILE D 1 216 ? 112.107 126.986 154.938 1.00 65.18 ? 216 ILE D C   1 
ATOM   11306 O O   . ILE D 1 216 ? 111.238 127.031 155.814 1.00 65.18 ? 216 ILE D O   1 
ATOM   11307 C CB  . ILE D 1 216 ? 111.498 126.268 152.591 1.00 65.18 ? 216 ILE D CB  1 
ATOM   11308 C CG1 . ILE D 1 216 ? 112.770 125.490 152.255 1.00 65.18 ? 216 ILE D CG1 1 
ATOM   11309 C CG2 . ILE D 1 216 ? 110.799 126.748 151.337 1.00 65.18 ? 216 ILE D CG2 1 
ATOM   11310 C CD1 . ILE D 1 216 ? 112.555 124.360 151.285 1.00 65.18 ? 216 ILE D CD1 1 
ATOM   11311 N N   . MET D 1 217 ? 113.335 126.544 155.192 1.00 68.03 ? 217 MET D N   1 
ATOM   11312 C CA  . MET D 1 217 ? 113.724 126.186 156.545 1.00 68.03 ? 217 MET D CA  1 
ATOM   11313 C C   . MET D 1 217 ? 113.909 127.401 157.435 1.00 68.03 ? 217 MET D C   1 
ATOM   11314 O O   . MET D 1 217 ? 114.025 127.242 158.652 1.00 68.03 ? 217 MET D O   1 
ATOM   11315 C CB  . MET D 1 217 ? 115.007 125.358 156.521 1.00 68.03 ? 217 MET D CB  1 
ATOM   11316 C CG  . MET D 1 217 ? 114.839 124.012 155.848 1.00 68.03 ? 217 MET D CG  1 
ATOM   11317 S SD  . MET D 1 217 ? 116.092 122.821 156.340 1.00 68.03 ? 217 MET D SD  1 
ATOM   11318 C CE  . MET D 1 217 ? 115.986 122.942 158.121 1.00 68.03 ? 217 MET D CE  1 
ATOM   11319 N N   . ASN D 1 218 ? 113.939 128.600 156.856 1.00 70.30 ? 218 ASN D N   1 
ATOM   11320 C CA  . ASN D 1 218 ? 114.039 129.844 157.614 1.00 70.30 ? 218 ASN D CA  1 
ATOM   11321 C C   . ASN D 1 218 ? 115.286 129.864 158.490 1.00 70.30 ? 218 ASN D C   1 
ATOM   11322 O O   . ASN D 1 218 ? 115.285 130.420 159.588 1.00 70.30 ? 218 ASN D O   1 
ATOM   11323 C CB  . ASN D 1 218 ? 112.782 130.081 158.451 1.00 70.30 ? 218 ASN D CB  1 
ATOM   11324 C CG  . ASN D 1 218 ? 111.558 130.341 157.599 1.00 70.30 ? 218 ASN D CG  1 
ATOM   11325 O OD1 . ASN D 1 218 ? 111.189 131.490 157.358 1.00 70.30 ? 218 ASN D OD1 1 
ATOM   11326 N ND2 . ASN D 1 218 ? 110.921 129.273 157.137 1.00 70.30 ? 218 ASN D ND2 1 
ATOM   11327 N N   . THR D 1 219 ? 116.358 129.255 158.003 1.00 68.88 ? 219 THR D N   1 
ATOM   11328 C CA  . THR D 1 219 ? 117.615 129.210 158.727 1.00 68.88 ? 219 THR D CA  1 
ATOM   11329 C C   . THR D 1 219 ? 118.698 129.923 157.933 1.00 68.88 ? 219 THR D C   1 
ATOM   11330 O O   . THR D 1 219 ? 118.519 130.268 156.764 1.00 68.88 ? 219 THR D O   1 
ATOM   11331 C CB  . THR D 1 219 ? 118.042 127.773 159.008 1.00 68.88 ? 219 THR D CB  1 
ATOM   11332 O OG1 . THR D 1 219 ? 118.217 127.088 157.767 1.00 68.88 ? 219 THR D OG1 1 
ATOM   11333 C CG2 . THR D 1 219 ? 116.981 127.063 159.823 1.00 68.88 ? 219 THR D CG2 1 
ATOM   11334 N N   . SER D 1 220 ? 119.832 130.140 158.588 1.00 70.80 ? 220 SER D N   1 
ATOM   11335 C CA  . SER D 1 220 ? 120.902 130.914 157.981 1.00 70.80 ? 220 SER D CA  1 
ATOM   11336 C C   . SER D 1 220 ? 121.664 130.083 156.961 1.00 70.80 ? 220 SER D C   1 
ATOM   11337 O O   . SER D 1 220 ? 121.898 128.886 157.154 1.00 70.80 ? 220 SER D O   1 
ATOM   11338 C CB  . SER D 1 220 ? 121.855 131.430 159.055 1.00 70.80 ? 220 SER D CB  1 
ATOM   11339 O OG  . SER D 1 220 ? 121.302 132.553 159.712 1.00 70.80 ? 220 SER D OG  1 
ATOM   11340 N N   . MET D 1 221 ? 122.045 130.739 155.863 1.00 71.67 ? 221 MET D N   1 
ATOM   11341 C CA  . MET D 1 221 ? 122.804 130.078 154.809 1.00 71.67 ? 221 MET D CA  1 
ATOM   11342 C C   . MET D 1 221 ? 124.048 129.415 155.374 1.00 71.67 ? 221 MET D C   1 
ATOM   11343 O O   . MET D 1 221 ? 124.344 128.248 155.081 1.00 71.67 ? 221 MET D O   1 
ATOM   11344 C CB  . MET D 1 221 ? 123.195 131.098 153.741 1.00 71.67 ? 221 MET D CB  1 
ATOM   11345 C CG  . MET D 1 221 ? 122.128 132.133 153.409 1.00 71.67 ? 221 MET D CG  1 
ATOM   11346 S SD  . MET D 1 221 ? 120.847 131.553 152.287 1.00 71.67 ? 221 MET D SD  1 
ATOM   11347 C CE  . MET D 1 221 ? 121.794 131.238 150.807 1.00 71.67 ? 221 MET D CE  1 
ATOM   11348 N N   . VAL D 1 222 ? 124.790 130.164 156.187 1.00 72.46 ? 222 VAL D N   1 
ATOM   11349 C CA  . VAL D 1 222 ? 126.011 129.649 156.798 1.00 72.46 ? 222 VAL D CA  1 
ATOM   11350 C C   . VAL D 1 222 ? 125.739 128.309 157.461 1.00 72.46 ? 222 VAL D C   1 
ATOM   11351 O O   . VAL D 1 222 ? 126.461 127.322 157.254 1.00 72.46 ? 222 VAL D O   1 
ATOM   11352 C CB  . VAL D 1 222 ? 126.555 130.673 157.810 1.00 72.46 ? 222 VAL D CB  1 
ATOM   11353 C CG1 . VAL D 1 222 ? 127.979 130.338 158.201 1.00 72.46 ? 222 VAL D CG1 1 
ATOM   11354 C CG2 . VAL D 1 222 ? 126.450 132.079 157.244 1.00 72.46 ? 222 VAL D CG2 1 
ATOM   11355 N N   . ASP D 1 223 ? 124.663 128.249 158.243 1.00 74.49 ? 223 ASP D N   1 
ATOM   11356 C CA  . ASP D 1 223 ? 124.417 127.084 159.077 1.00 74.49 ? 223 ASP D CA  1 
ATOM   11357 C C   . ASP D 1 223 ? 124.094 125.854 158.245 1.00 74.49 ? 223 ASP D C   1 
ATOM   11358 O O   . ASP D 1 223 ? 124.681 124.790 158.460 1.00 74.49 ? 223 ASP D O   1 
ATOM   11359 C CB  . ASP D 1 223 ? 123.303 127.376 160.074 1.00 74.49 ? 223 ASP D CB  1 
ATOM   11360 C CG  . ASP D 1 223 ? 123.740 128.334 161.153 1.00 74.49 ? 223 ASP D CG  1 
ATOM   11361 O OD1 . ASP D 1 223 ? 124.942 128.328 161.490 1.00 74.49 ? 223 ASP D OD1 1 
ATOM   11362 O OD2 . ASP D 1 223 ? 122.886 129.086 161.665 1.00 74.49 ? 223 ASP D OD2 1 
ATOM   11363 N N   . ILE D 1 224 ? 123.159 125.962 157.301 1.00 68.70 ? 224 ILE D N   1 
ATOM   11364 C CA  . ILE D 1 224 ? 122.820 124.772 156.529 1.00 68.70 ? 224 ILE D CA  1 
ATOM   11365 C C   . ILE D 1 224 ? 124.009 124.324 155.695 1.00 68.70 ? 224 ILE D C   1 
ATOM   11366 O O   . ILE D 1 224 ? 124.304 123.127 155.608 1.00 68.70 ? 224 ILE D O   1 
ATOM   11367 C CB  . ILE D 1 224 ? 121.574 125.004 155.661 1.00 68.70 ? 224 ILE D CB  1 
ATOM   11368 C CG1 . ILE D 1 224 ? 121.753 126.199 154.754 1.00 68.70 ? 224 ILE D CG1 1 
ATOM   11369 C CG2 . ILE D 1 224 ? 120.371 125.227 156.528 1.00 68.70 ? 224 ILE D CG2 1 
ATOM   11370 C CD1 . ILE D 1 224 ? 120.594 126.386 153.872 1.00 68.70 ? 224 ILE D CD1 1 
ATOM   11371 N N   . MET D 1 225 ? 124.731 125.272 155.095 1.00 69.84 ? 225 MET D N   1 
ATOM   11372 C CA  . MET D 1 225 ? 125.885 124.899 154.288 1.00 69.84 ? 225 MET D CA  1 
ATOM   11373 C C   . MET D 1 225 ? 126.896 124.114 155.110 1.00 69.84 ? 225 MET D C   1 
ATOM   11374 O O   . MET D 1 225 ? 127.326 123.018 154.721 1.00 69.84 ? 225 MET D O   1 
ATOM   11375 C CB  . MET D 1 225 ? 126.533 126.146 153.696 1.00 69.84 ? 225 MET D CB  1 
ATOM   11376 C CG  . MET D 1 225 ? 125.771 126.756 152.535 1.00 69.84 ? 225 MET D CG  1 
ATOM   11377 S SD  . MET D 1 225 ? 126.640 128.153 151.807 1.00 69.84 ? 225 MET D SD  1 
ATOM   11378 C CE  . MET D 1 225 ? 125.271 129.204 151.342 1.00 69.84 ? 225 MET D CE  1 
ATOM   11379 N N   . PHE D 1 226 ? 127.271 124.647 156.270 1.00 70.91 ? 226 PHE D N   1 
ATOM   11380 C CA  . PHE D 1 226 ? 128.342 124.011 157.022 1.00 70.91 ? 226 PHE D CA  1 
ATOM   11381 C C   . PHE D 1 226 ? 127.872 122.774 157.768 1.00 70.91 ? 226 PHE D C   1 
ATOM   11382 O O   . PHE D 1 226 ? 128.662 121.853 157.979 1.00 70.91 ? 226 PHE D O   1 
ATOM   11383 C CB  . PHE D 1 226 ? 128.973 125.027 157.956 1.00 70.91 ? 226 PHE D CB  1 
ATOM   11384 C CG  . PHE D 1 226 ? 129.812 126.020 157.236 1.00 70.91 ? 226 PHE D CG  1 
ATOM   11385 C CD1 . PHE D 1 226 ? 130.945 125.610 156.561 1.00 70.91 ? 226 PHE D CD1 1 
ATOM   11386 C CD2 . PHE D 1 226 ? 129.452 127.349 157.186 1.00 70.91 ? 226 PHE D CD2 1 
ATOM   11387 C CE1 . PHE D 1 226 ? 131.718 126.513 155.878 1.00 70.91 ? 226 PHE D CE1 1 
ATOM   11388 C CE2 . PHE D 1 226 ? 130.221 128.258 156.506 1.00 70.91 ? 226 PHE D CE2 1 
ATOM   11389 C CZ  . PHE D 1 226 ? 131.355 127.839 155.849 1.00 70.91 ? 226 PHE D CZ  1 
ATOM   11390 N N   . ASP D 1 227 ? 126.594 122.691 158.117 1.00 69.80 ? 227 ASP D N   1 
ATOM   11391 C CA  . ASP D 1 227 ? 126.090 121.455 158.691 1.00 69.80 ? 227 ASP D CA  1 
ATOM   11392 C C   . ASP D 1 227 ? 126.055 120.347 157.651 1.00 69.80 ? 227 ASP D C   1 
ATOM   11393 O O   . ASP D 1 227 ? 126.324 119.182 157.967 1.00 69.80 ? 227 ASP D O   1 
ATOM   11394 C CB  . ASP D 1 227 ? 124.708 121.685 159.291 1.00 69.80 ? 227 ASP D CB  1 
ATOM   11395 C CG  . ASP D 1 227 ? 124.758 122.525 160.549 1.00 69.80 ? 227 ASP D CG  1 
ATOM   11396 O OD1 . ASP D 1 227 ? 125.853 123.021 160.893 1.00 69.80 ? 227 ASP D OD1 1 
ATOM   11397 O OD2 . ASP D 1 227 ? 123.705 122.690 161.196 1.00 69.80 ? 227 ASP D OD2 1 
ATOM   11398 N N   . ALA D 1 228 ? 125.738 120.687 156.401 1.00 65.88 ? 228 ALA D N   1 
ATOM   11399 C CA  . ALA D 1 228 ? 125.810 119.695 155.337 1.00 65.88 ? 228 ALA D CA  1 
ATOM   11400 C C   . ALA D 1 228 ? 127.239 119.209 155.144 1.00 65.88 ? 228 ALA D C   1 
ATOM   11401 O O   . ALA D 1 228 ? 127.495 117.999 155.080 1.00 65.88 ? 228 ALA D O   1 
ATOM   11402 C CB  . ALA D 1 228 ? 125.254 120.277 154.042 1.00 65.88 ? 228 ALA D CB  1 
ATOM   11403 N N   . VAL D 1 229 ? 128.192 120.137 155.057 1.00 69.88 ? 229 VAL D N   1 
ATOM   11404 C CA  . VAL D 1 229 ? 129.570 119.687 154.880 1.00 69.88 ? 229 VAL D CA  1 
ATOM   11405 C C   . VAL D 1 229 ? 130.033 118.879 156.089 1.00 69.88 ? 229 VAL D C   1 
ATOM   11406 O O   . VAL D 1 229 ? 130.826 117.943 155.950 1.00 69.88 ? 229 VAL D O   1 
ATOM   11407 C CB  . VAL D 1 229 ? 130.516 120.867 154.577 1.00 69.88 ? 229 VAL D CB  1 
ATOM   11408 C CG1 . VAL D 1 229 ? 130.799 121.681 155.812 1.00 69.88 ? 229 VAL D CG1 1 
ATOM   11409 C CG2 . VAL D 1 229 ? 131.814 120.349 153.995 1.00 69.88 ? 229 VAL D CG2 1 
ATOM   11410 N N   . GLU D 1 230 ? 129.510 119.180 157.279 1.00 72.88 ? 230 GLU D N   1 
ATOM   11411 C CA  . GLU D 1 230 ? 129.915 118.442 158.469 1.00 72.88 ? 230 GLU D CA  1 
ATOM   11412 C C   . GLU D 1 230 ? 129.371 117.021 158.452 1.00 72.88 ? 230 GLU D C   1 
ATOM   11413 O O   . GLU D 1 230 ? 130.089 116.062 158.771 1.00 72.88 ? 230 GLU D O   1 
ATOM   11414 C CB  . GLU D 1 230 ? 129.440 119.176 159.718 1.00 72.88 ? 230 GLU D CB  1 
ATOM   11415 C CG  . GLU D 1 230 ? 129.667 118.403 160.986 1.00 72.88 ? 230 GLU D CG  1 
ATOM   11416 C CD  . GLU D 1 230 ? 131.123 118.070 161.186 1.00 72.88 ? 230 GLU D CD  1 
ATOM   11417 O OE1 . GLU D 1 230 ? 131.973 118.928 160.878 1.00 72.88 ? 230 GLU D OE1 1 
ATOM   11418 O OE2 . GLU D 1 230 ? 131.425 116.952 161.645 1.00 72.88 ? 230 GLU D OE2 1 
ATOM   11419 N N   . SER D 1 231 ? 128.092 116.868 158.109 1.00 68.75 ? 231 SER D N   1 
ATOM   11420 C CA  . SER D 1 231 ? 127.531 115.528 158.016 1.00 68.75 ? 231 SER D CA  1 
ATOM   11421 C C   . SER D 1 231 ? 128.261 114.717 156.961 1.00 68.75 ? 231 SER D C   1 
ATOM   11422 O O   . SER D 1 231 ? 128.479 113.515 157.137 1.00 68.75 ? 231 SER D O   1 
ATOM   11423 C CB  . SER D 1 231 ? 126.038 115.581 157.705 1.00 68.75 ? 231 SER D CB  1 
ATOM   11424 O OG  . SER D 1 231 ? 125.806 115.957 156.366 1.00 68.75 ? 231 SER D OG  1 
ATOM   11425 N N   . PHE D 1 232 ? 128.667 115.357 155.864 1.00 67.61 ? 232 PHE D N   1 
ATOM   11426 C CA  . PHE D 1 232 ? 129.446 114.627 154.872 1.00 67.61 ? 232 PHE D CA  1 
ATOM   11427 C C   . PHE D 1 232 ? 130.806 114.239 155.423 1.00 67.61 ? 232 PHE D C   1 
ATOM   11428 O O   . PHE D 1 232 ? 131.310 113.147 155.143 1.00 67.61 ? 232 PHE D O   1 
ATOM   11429 C CB  . PHE D 1 232 ? 129.613 115.450 153.599 1.00 67.61 ? 232 PHE D CB  1 
ATOM   11430 C CG  . PHE D 1 232 ? 130.279 114.696 152.487 1.00 67.61 ? 232 PHE D CG  1 
ATOM   11431 C CD1 . PHE D 1 232 ? 129.597 113.714 151.797 1.00 67.61 ? 232 PHE D CD1 1 
ATOM   11432 C CD2 . PHE D 1 232 ? 131.589 114.951 152.149 1.00 67.61 ? 232 PHE D CD2 1 
ATOM   11433 C CE1 . PHE D 1 232 ? 130.206 113.013 150.788 1.00 67.61 ? 232 PHE D CE1 1 
ATOM   11434 C CE2 . PHE D 1 232 ? 132.200 114.250 151.141 1.00 67.61 ? 232 PHE D CE2 1 
ATOM   11435 C CZ  . PHE D 1 232 ? 131.507 113.281 150.461 1.00 67.61 ? 232 PHE D CZ  1 
ATOM   11436 N N   . ARG D 1 233 ? 131.421 115.128 156.200 1.00 76.02 ? 233 ARG D N   1 
ATOM   11437 C CA  . ARG D 1 233 ? 132.715 114.817 156.793 1.00 76.02 ? 233 ARG D CA  1 
ATOM   11438 C C   . ARG D 1 233 ? 132.634 113.588 157.681 1.00 76.02 ? 233 ARG D C   1 
ATOM   11439 O O   . ARG D 1 233 ? 133.534 112.741 157.671 1.00 76.02 ? 233 ARG D O   1 
ATOM   11440 C CB  . ARG D 1 233 ? 133.216 116.009 157.595 1.00 76.02 ? 233 ARG D CB  1 
ATOM   11441 C CG  . ARG D 1 233 ? 133.797 117.100 156.754 1.00 76.02 ? 233 ARG D CG  1 
ATOM   11442 C CD  . ARG D 1 233 ? 134.548 118.056 157.635 1.00 76.02 ? 233 ARG D CD  1 
ATOM   11443 N NE  . ARG D 1 233 ? 135.234 117.351 158.707 1.00 76.02 ? 233 ARG D NE  1 
ATOM   11444 C CZ  . ARG D 1 233 ? 135.934 117.951 159.659 1.00 76.02 ? 233 ARG D CZ  1 
ATOM   11445 N NH1 . ARG D 1 233 ? 136.040 119.270 159.670 1.00 76.02 ? 233 ARG D NH1 1 
ATOM   11446 N NH2 . ARG D 1 233 ? 136.529 117.231 160.598 1.00 76.02 ? 233 ARG D NH2 1 
ATOM   11447 N N   . LYS D 1 234 ? 131.562 113.471 158.457 1.00 75.66 ? 234 LYS D N   1 
ATOM   11448 C CA  . LYS D 1 234 ? 131.476 112.341 159.375 1.00 75.66 ? 234 LYS D CA  1 
ATOM   11449 C C   . LYS D 1 234 ? 131.051 111.071 158.652 1.00 75.66 ? 234 LYS D C   1 
ATOM   11450 O O   . LYS D 1 234 ? 131.632 110.003 158.869 1.00 75.66 ? 234 LYS D O   1 
ATOM   11451 C CB  . LYS D 1 234 ? 130.529 112.661 160.526 1.00 75.66 ? 234 LYS D CB  1 
ATOM   11452 C CG  . LYS D 1 234 ? 130.964 113.858 161.361 1.00 75.66 ? 234 LYS D CG  1 
ATOM   11453 C CD  . LYS D 1 234 ? 132.260 113.600 162.135 1.00 75.66 ? 234 LYS D CD  1 
ATOM   11454 C CE  . LYS D 1 234 ? 133.483 114.194 161.427 1.00 75.66 ? 234 LYS D CE  1 
ATOM   11455 N NZ  . LYS D 1 234 ? 134.733 114.043 162.218 1.00 75.66 ? 234 LYS D NZ  1 
ATOM   11456 N N   . GLN D 1 235 ? 130.049 111.164 157.779 1.00 72.90 ? 235 GLN D N   1 
ATOM   11457 C CA  . GLN D 1 235 ? 129.602 110.003 157.021 1.00 72.90 ? 235 GLN D CA  1 
ATOM   11458 C C   . GLN D 1 235 ? 130.693 109.451 156.116 1.00 72.90 ? 235 GLN D C   1 
ATOM   11459 O O   . GLN D 1 235 ? 130.720 108.246 155.860 1.00 72.90 ? 235 GLN D O   1 
ATOM   11460 C CB  . GLN D 1 235 ? 128.368 110.381 156.198 1.00 72.90 ? 235 GLN D CB  1 
ATOM   11461 C CG  . GLN D 1 235 ? 127.812 109.283 155.320 1.00 72.90 ? 235 GLN D CG  1 
ATOM   11462 C CD  . GLN D 1 235 ? 128.517 109.213 153.990 1.00 72.90 ? 235 GLN D CD  1 
ATOM   11463 O OE1 . GLN D 1 235 ? 129.132 110.182 153.558 1.00 72.90 ? 235 GLN D OE1 1 
ATOM   11464 N NE2 . GLN D 1 235 ? 128.449 108.062 153.340 1.00 72.90 ? 235 GLN D NE2 1 
ATOM   11465 N N   . SER D 1 236 ? 131.590 110.298 155.627 1.00 73.95 ? 236 SER D N   1 
ATOM   11466 C CA  . SER D 1 236 ? 132.626 109.879 154.697 1.00 73.95 ? 236 SER D CA  1 
ATOM   11467 C C   . SER D 1 236 ? 133.980 109.705 155.352 1.00 73.95 ? 236 SER D C   1 
ATOM   11468 O O   . SER D 1 236 ? 134.825 108.980 154.817 1.00 73.95 ? 236 SER D O   1 
ATOM   11469 C CB  . SER D 1 236 ? 132.757 110.902 153.565 1.00 73.95 ? 236 SER D CB  1 
ATOM   11470 O OG  . SER D 1 236 ? 133.030 112.192 154.079 1.00 73.95 ? 236 SER D OG  1 
ATOM   11471 N N   . GLY D 1 237 ? 134.210 110.359 156.486 1.00 78.51 ? 237 GLY D N   1 
ATOM   11472 C CA  . GLY D 1 237 ? 135.504 110.335 157.112 1.00 78.51 ? 237 GLY D CA  1 
ATOM   11473 C C   . GLY D 1 237 ? 136.517 111.275 156.508 1.00 78.51 ? 237 GLY D C   1 
ATOM   11474 O O   . GLY D 1 237 ? 137.568 111.500 157.121 1.00 78.51 ? 237 GLY D O   1 
ATOM   11475 N N   . LEU D 1 238 ? 136.245 111.838 155.337 1.00 77.99 ? 238 LEU D N   1 
ATOM   11476 C CA  . LEU D 1 238 ? 137.227 112.690 154.694 1.00 77.99 ? 238 LEU D CA  1 
ATOM   11477 C C   . LEU D 1 238 ? 137.290 114.049 155.385 1.00 77.99 ? 238 LEU D C   1 
ATOM   11478 O O   . LEU D 1 238 ? 136.374 114.456 156.103 1.00 77.99 ? 238 LEU D O   1 
ATOM   11479 C CB  . LEU D 1 238 ? 136.912 112.852 153.208 1.00 77.99 ? 238 LEU D CB  1 
ATOM   11480 C CG  . LEU D 1 238 ? 137.222 111.631 152.338 1.00 77.99 ? 238 LEU D CG  1 
ATOM   11481 C CD1 . LEU D 1 238 ? 136.051 110.676 152.295 1.00 77.99 ? 238 LEU D CD1 1 
ATOM   11482 C CD2 . LEU D 1 238 ? 137.614 112.043 150.941 1.00 77.99 ? 238 LEU D CD2 1 
ATOM   11483 N N   . TYR D 1 239 ? 138.392 114.753 155.147 1.00 82.98 ? 239 TYR D N   1 
ATOM   11484 C CA  . TYR D 1 239 ? 138.760 115.942 155.902 1.00 82.98 ? 239 TYR D CA  1 
ATOM   11485 C C   . TYR D 1 239 ? 138.472 117.187 155.074 1.00 82.98 ? 239 TYR D C   1 
ATOM   11486 O O   . TYR D 1 239 ? 139.192 117.470 154.114 1.00 82.98 ? 239 TYR D O   1 
ATOM   11487 C CB  . TYR D 1 239 ? 140.240 115.879 156.272 1.00 82.98 ? 239 TYR D CB  1 
ATOM   11488 C CG  . TYR D 1 239 ? 140.663 116.813 157.375 1.00 82.98 ? 239 TYR D CG  1 
ATOM   11489 C CD1 . TYR D 1 239 ? 140.467 118.181 157.271 1.00 82.98 ? 239 TYR D CD1 1 
ATOM   11490 C CD2 . TYR D 1 239 ? 141.288 116.328 158.510 1.00 82.98 ? 239 TYR D CD2 1 
ATOM   11491 C CE1 . TYR D 1 239 ? 140.855 119.034 158.273 1.00 82.98 ? 239 TYR D CE1 1 
ATOM   11492 C CE2 . TYR D 1 239 ? 141.688 117.175 159.518 1.00 82.98 ? 239 TYR D CE2 1 
ATOM   11493 C CZ  . TYR D 1 239 ? 141.471 118.528 159.393 1.00 82.98 ? 239 TYR D CZ  1 
ATOM   11494 O OH  . TYR D 1 239 ? 141.867 119.379 160.399 1.00 82.98 ? 239 TYR D OH  1 
ATOM   11495 N N   . PHE D 1 240 ? 137.449 117.944 155.462 1.00 78.63 ? 240 PHE D N   1 
ATOM   11496 C CA  . PHE D 1 240 ? 137.086 119.192 154.788 1.00 78.63 ? 240 PHE D CA  1 
ATOM   11497 C C   . PHE D 1 240 ? 137.124 120.321 155.813 1.00 78.63 ? 240 PHE D C   1 
ATOM   11498 O O   . PHE D 1 240 ? 136.108 120.618 156.446 1.00 78.63 ? 240 PHE D O   1 
ATOM   11499 C CB  . PHE D 1 240 ? 135.706 119.097 154.145 1.00 78.63 ? 240 PHE D CB  1 
ATOM   11500 C CG  . PHE D 1 240 ? 135.659 118.245 152.916 1.00 78.63 ? 240 PHE D CG  1 
ATOM   11501 C CD1 . PHE D 1 240 ? 136.651 118.327 151.962 1.00 78.63 ? 240 PHE D CD1 1 
ATOM   11502 C CD2 . PHE D 1 240 ? 134.607 117.382 152.701 1.00 78.63 ? 240 PHE D CD2 1 
ATOM   11503 C CE1 . PHE D 1 240 ? 136.602 117.554 150.825 1.00 78.63 ? 240 PHE D CE1 1 
ATOM   11504 C CE2 . PHE D 1 240 ? 134.557 116.606 151.564 1.00 78.63 ? 240 PHE D CE2 1 
ATOM   11505 C CZ  . PHE D 1 240 ? 135.556 116.691 150.628 1.00 78.63 ? 240 PHE D CZ  1 
ATOM   11506 N N   . ASP D 1 241 ? 138.276 120.963 155.975 1.00 81.81 ? 241 ASP D N   1 
ATOM   11507 C CA  . ASP D 1 241 ? 138.396 122.002 156.992 1.00 81.81 ? 241 ASP D CA  1 
ATOM   11508 C C   . ASP D 1 241 ? 137.511 123.183 156.617 1.00 81.81 ? 241 ASP D C   1 
ATOM   11509 O O   . ASP D 1 241 ? 137.772 123.876 155.631 1.00 81.81 ? 241 ASP D O   1 
ATOM   11510 C CB  . ASP D 1 241 ? 139.846 122.438 157.156 1.00 81.81 ? 241 ASP D CB  1 
ATOM   11511 C CG  . ASP D 1 241 ? 140.083 123.164 158.466 1.00 81.81 ? 241 ASP D CG  1 
ATOM   11512 O OD1 . ASP D 1 241 ? 139.968 122.520 159.529 1.00 81.81 ? 241 ASP D OD1 1 
ATOM   11513 O OD2 . ASP D 1 241 ? 140.371 124.378 158.438 1.00 81.81 ? 241 ASP D OD2 1 
ATOM   11514 N N   . TYR D 1 242 ? 136.470 123.418 157.413 1.00 77.49 ? 242 TYR D N   1 
ATOM   11515 C CA  . TYR D 1 242 ? 135.475 124.447 157.138 1.00 77.49 ? 242 TYR D CA  1 
ATOM   11516 C C   . TYR D 1 242 ? 135.330 125.455 158.271 1.00 77.49 ? 242 TYR D C   1 
ATOM   11517 O O   . TYR D 1 242 ? 134.408 126.274 158.236 1.00 77.49 ? 242 TYR D O   1 
ATOM   11518 C CB  . TYR D 1 242 ? 134.118 123.799 156.876 1.00 77.49 ? 242 TYR D CB  1 
ATOM   11519 C CG  . TYR D 1 242 ? 133.559 123.154 158.115 1.00 77.49 ? 242 TYR D CG  1 
ATOM   11520 C CD1 . TYR D 1 242 ? 134.000 121.910 158.525 1.00 77.49 ? 242 TYR D CD1 1 
ATOM   11521 C CD2 . TYR D 1 242 ? 132.609 123.799 158.891 1.00 77.49 ? 242 TYR D CD2 1 
ATOM   11522 C CE1 . TYR D 1 242 ? 133.502 121.318 159.662 1.00 77.49 ? 242 TYR D CE1 1 
ATOM   11523 C CE2 . TYR D 1 242 ? 132.104 123.214 160.030 1.00 77.49 ? 242 TYR D CE2 1 
ATOM   11524 C CZ  . TYR D 1 242 ? 132.555 121.972 160.410 1.00 77.49 ? 242 TYR D CZ  1 
ATOM   11525 O OH  . TYR D 1 242 ? 132.060 121.376 161.545 1.00 77.49 ? 242 TYR D OH  1 
ATOM   11526 N N   . THR D 1 243 ? 136.192 125.413 159.281 1.00 78.75 ? 243 THR D N   1 
ATOM   11527 C CA  . THR D 1 243 ? 135.967 126.241 160.459 1.00 78.75 ? 243 THR D CA  1 
ATOM   11528 C C   . THR D 1 243 ? 136.196 127.719 160.163 1.00 78.75 ? 243 THR D C   1 
ATOM   11529 O O   . THR D 1 243 ? 135.346 128.557 160.474 1.00 78.75 ? 243 THR D O   1 
ATOM   11530 C CB  . THR D 1 243 ? 136.845 125.762 161.617 1.00 78.75 ? 243 THR D CB  1 
ATOM   11531 O OG1 . THR D 1 243 ? 136.691 126.648 162.731 1.00 78.75 ? 243 THR D OG1 1 
ATOM   11532 C CG2 . THR D 1 243 ? 138.306 125.662 161.217 1.00 78.75 ? 243 THR D CG2 1 
ATOM   11533 N N   . LYS D 1 244 ? 137.325 128.059 159.542 1.00 75.82 ? 244 LYS D N   1 
ATOM   11534 C CA  . LYS D 1 244 ? 137.694 129.461 159.393 1.00 75.82 ? 244 LYS D CA  1 
ATOM   11535 C C   . LYS D 1 244 ? 136.703 130.206 158.516 1.00 75.82 ? 244 LYS D C   1 
ATOM   11536 O O   . LYS D 1 244 ? 136.404 131.382 158.762 1.00 75.82 ? 244 LYS D O   1 
ATOM   11537 C CB  . LYS D 1 244 ? 139.100 129.561 158.820 1.00 75.82 ? 244 LYS D CB  1 
ATOM   11538 C CG  . LYS D 1 244 ? 140.103 128.772 159.607 1.00 75.82 ? 244 LYS D CG  1 
ATOM   11539 C CD  . LYS D 1 244 ? 141.333 128.493 158.790 1.00 75.82 ? 244 LYS D CD  1 
ATOM   11540 C CE  . LYS D 1 244 ? 141.023 127.520 157.680 1.00 75.82 ? 244 LYS D CE  1 
ATOM   11541 N NZ  . LYS D 1 244 ? 142.256 127.171 156.931 1.00 75.82 ? 244 LYS D NZ  1 
ATOM   11542 N N   . ILE D 1 245 ? 136.188 129.540 157.483 1.00 76.05 ? 245 ILE D N   1 
ATOM   11543 C CA  . ILE D 1 245 ? 135.189 130.173 156.634 1.00 76.05 ? 245 ILE D CA  1 
ATOM   11544 C C   . ILE D 1 245 ? 133.975 130.552 157.458 1.00 76.05 ? 245 ILE D C   1 
ATOM   11545 O O   . ILE D 1 245 ? 133.416 131.640 157.302 1.00 76.05 ? 245 ILE D O   1 
ATOM   11546 C CB  . ILE D 1 245 ? 134.804 129.249 155.468 1.00 76.05 ? 245 ILE D CB  1 
ATOM   11547 C CG1 . ILE D 1 245 ? 136.033 128.834 154.673 1.00 76.05 ? 245 ILE D CG1 1 
ATOM   11548 C CG2 . ILE D 1 245 ? 133.832 129.939 154.546 1.00 76.05 ? 245 ILE D CG2 1 
ATOM   11549 C CD1 . ILE D 1 245 ? 135.707 127.897 153.535 1.00 76.05 ? 245 ILE D CD1 1 
ATOM   11550 N N   . LYS D 1 246 ? 133.546 129.658 158.343 1.00 76.99 ? 246 LYS D N   1 
ATOM   11551 C CA  . LYS D 1 246 ? 132.393 129.944 159.185 1.00 76.99 ? 246 LYS D CA  1 
ATOM   11552 C C   . LYS D 1 246 ? 132.694 131.084 160.151 1.00 76.99 ? 246 LYS D C   1 
ATOM   11553 O O   . LYS D 1 246 ? 131.877 131.997 160.327 1.00 76.99 ? 246 LYS D O   1 
ATOM   11554 C CB  . LYS D 1 246 ? 131.994 128.676 159.934 1.00 76.99 ? 246 LYS D CB  1 
ATOM   11555 C CG  . LYS D 1 246 ? 130.528 128.559 160.262 1.00 76.99 ? 246 LYS D CG  1 
ATOM   11556 C CD  . LYS D 1 246 ? 130.275 127.299 161.058 1.00 76.99 ? 246 LYS D CD  1 
ATOM   11557 C CE  . LYS D 1 246 ? 128.955 127.369 161.795 1.00 76.99 ? 246 LYS D CE  1 
ATOM   11558 N NZ  . LYS D 1 246 ? 128.837 126.273 162.791 1.00 76.99 ? 246 LYS D NZ  1 
ATOM   11559 N N   . GLU D 1 247 ? 133.879 131.052 160.765 1.00 78.97 ? 247 GLU D N   1 
ATOM   11560 C CA  . GLU D 1 247 ? 134.283 132.107 161.686 1.00 78.97 ? 247 GLU D CA  1 
ATOM   11561 C C   . GLU D 1 247 ? 134.248 133.469 161.013 1.00 78.97 ? 247 GLU D C   1 
ATOM   11562 O O   . GLU D 1 247 ? 133.862 134.466 161.631 1.00 78.97 ? 247 GLU D O   1 
ATOM   11563 C CB  . GLU D 1 247 ? 135.686 131.821 162.213 1.00 78.97 ? 247 GLU D CB  1 
ATOM   11564 C CG  . GLU D 1 247 ? 135.837 130.466 162.867 1.00 78.97 ? 247 GLU D CG  1 
ATOM   11565 C CD  . GLU D 1 247 ? 137.281 130.025 162.946 1.00 78.97 ? 247 GLU D CD  1 
ATOM   11566 O OE1 . GLU D 1 247 ? 138.150 130.733 162.401 1.00 78.97 ? 247 GLU D OE1 1 
ATOM   11567 O OE2 . GLU D 1 247 ? 137.551 128.962 163.541 1.00 78.97 ? 247 GLU D OE2 1 
ATOM   11568 N N   . PHE D 1 248 ? 134.653 133.537 159.747 1.00 78.18 ? 248 PHE D N   1 
ATOM   11569 C CA  . PHE D 1 248 ? 134.658 134.836 159.086 1.00 78.18 ? 248 PHE D CA  1 
ATOM   11570 C C   . PHE D 1 248 ? 133.283 135.226 158.564 1.00 78.18 ? 248 PHE D C   1 
ATOM   11571 O O   . PHE D 1 248 ? 132.842 136.360 158.769 1.00 78.18 ? 248 PHE D O   1 
ATOM   11572 C CB  . PHE D 1 248 ? 135.652 134.866 157.935 1.00 78.18 ? 248 PHE D CB  1 
ATOM   11573 C CG  . PHE D 1 248 ? 135.531 136.100 157.091 1.00 78.18 ? 248 PHE D CG  1 
ATOM   11574 C CD1 . PHE D 1 248 ? 135.915 137.327 157.589 1.00 78.18 ? 248 PHE D CD1 1 
ATOM   11575 C CD2 . PHE D 1 248 ? 134.999 136.038 155.819 1.00 78.18 ? 248 PHE D CD2 1 
ATOM   11576 C CE1 . PHE D 1 248 ? 135.809 138.454 156.823 1.00 78.18 ? 248 PHE D CE1 1 
ATOM   11577 C CE2 . PHE D 1 248 ? 134.882 137.169 155.055 1.00 78.18 ? 248 PHE D CE2 1 
ATOM   11578 C CZ  . PHE D 1 248 ? 135.287 138.378 155.557 1.00 78.18 ? 248 PHE D CZ  1 
ATOM   11579 N N   . MET D 1 249 ? 132.602 134.328 157.864 1.00 77.63 ? 249 MET D N   1 
ATOM   11580 C CA  . MET D 1 249 ? 131.311 134.670 157.297 1.00 77.63 ? 249 MET D CA  1 
ATOM   11581 C C   . MET D 1 249 ? 130.236 134.849 158.352 1.00 77.63 ? 249 MET D C   1 
ATOM   11582 O O   . MET D 1 249 ? 129.144 135.317 158.020 1.00 77.63 ? 249 MET D O   1 
ATOM   11583 C CB  . MET D 1 249 ? 130.872 133.599 156.303 1.00 77.63 ? 249 MET D CB  1 
ATOM   11584 C CG  . MET D 1 249 ? 131.634 133.612 154.997 1.00 77.63 ? 249 MET D CG  1 
ATOM   11585 S SD  . MET D 1 249 ? 131.183 132.227 153.939 1.00 77.63 ? 249 MET D SD  1 
ATOM   11586 C CE  . MET D 1 249 ? 129.421 132.480 153.751 1.00 77.63 ? 249 MET D CE  1 
ATOM   11587 N N   . SER D 1 250 ? 130.510 134.490 159.605 1.00 81.23 ? 250 SER D N   1 
ATOM   11588 C CA  . SER D 1 250 ? 129.512 134.647 160.652 1.00 81.23 ? 250 SER D CA  1 
ATOM   11589 C C   . SER D 1 250 ? 129.536 136.027 161.293 1.00 81.23 ? 250 SER D C   1 
ATOM   11590 O O   . SER D 1 250 ? 128.616 136.356 162.048 1.00 81.23 ? 250 SER D O   1 
ATOM   11591 C CB  . SER D 1 250 ? 129.707 133.575 161.721 1.00 81.23 ? 250 SER D CB  1 
ATOM   11592 O OG  . SER D 1 250 ? 129.465 132.288 161.183 1.00 81.23 ? 250 SER D OG  1 
ATOM   11593 N N   . GLU D 1 251 ? 130.545 136.843 160.998 1.00 83.58 ? 251 GLU D N   1 
ATOM   11594 C CA  . GLU D 1 251 ? 130.678 138.148 161.626 1.00 83.58 ? 251 GLU D CA  1 
ATOM   11595 C C   . GLU D 1 251 ? 129.607 139.112 161.118 1.00 83.58 ? 251 GLU D C   1 
ATOM   11596 O O   . GLU D 1 251 ? 128.690 138.747 160.379 1.00 83.58 ? 251 GLU D O   1 
ATOM   11597 C CB  . GLU D 1 251 ? 132.058 138.735 161.355 1.00 83.58 ? 251 GLU D CB  1 
ATOM   11598 C CG  . GLU D 1 251 ? 133.186 137.784 161.627 1.00 83.58 ? 251 GLU D CG  1 
ATOM   11599 C CD  . GLU D 1 251 ? 134.373 138.029 160.727 1.00 83.58 ? 251 GLU D CD  1 
ATOM   11600 O OE1 . GLU D 1 251 ? 134.266 138.867 159.810 1.00 83.58 ? 251 GLU D OE1 1 
ATOM   11601 O OE2 . GLU D 1 251 ? 135.412 137.373 160.931 1.00 83.58 ? 251 GLU D OE2 1 
ATOM   11602 N N   . GLU D 1 252 ? 129.736 140.368 161.539 1.00 87.87 ? 252 GLU D N   1 
ATOM   11603 C CA  . GLU D 1 252 ? 128.800 141.417 161.163 1.00 87.87 ? 252 GLU D CA  1 
ATOM   11604 C C   . GLU D 1 252 ? 129.403 142.471 160.248 1.00 87.87 ? 252 GLU D C   1 
ATOM   11605 O O   . GLU D 1 252 ? 128.708 142.966 159.362 1.00 87.87 ? 252 GLU D O   1 
ATOM   11606 C CB  . GLU D 1 252 ? 128.248 142.093 162.423 1.00 87.87 ? 252 GLU D CB  1 
ATOM   11607 C CG  . GLU D 1 252 ? 129.253 142.962 163.160 1.00 87.87 ? 252 GLU D CG  1 
ATOM   11608 C CD  . GLU D 1 252 ? 130.211 142.167 164.025 1.00 87.87 ? 252 GLU D CD  1 
ATOM   11609 O OE1 . GLU D 1 252 ? 130.313 140.935 163.846 1.00 87.87 ? 252 GLU D OE1 1 
ATOM   11610 O OE2 . GLU D 1 252 ? 130.872 142.780 164.887 1.00 87.87 ? 252 GLU D OE2 1 
ATOM   11611 N N   . LYS D 1 253 ? 130.681 142.815 160.426 1.00 88.24 ? 253 LYS D N   1 
ATOM   11612 C CA  . LYS D 1 253 ? 131.322 143.756 159.515 1.00 88.24 ? 253 LYS D CA  1 
ATOM   11613 C C   . LYS D 1 253 ? 131.427 143.161 158.120 1.00 88.24 ? 253 LYS D C   1 
ATOM   11614 O O   . LYS D 1 253 ? 131.334 143.876 157.116 1.00 88.24 ? 253 LYS D O   1 
ATOM   11615 C CB  . LYS D 1 253 ? 132.701 144.151 160.049 1.00 88.24 ? 253 LYS D CB  1 
ATOM   11616 C CG  . LYS D 1 253 ? 133.241 145.443 159.467 1.00 88.24 ? 253 LYS D CG  1 
ATOM   11617 C CD  . LYS D 1 253 ? 134.687 145.670 159.868 1.00 88.24 ? 253 LYS D CD  1 
ATOM   11618 C CE  . LYS D 1 253 ? 135.608 144.672 159.191 1.00 88.24 ? 253 LYS D CE  1 
ATOM   11619 N NZ  . LYS D 1 253 ? 135.682 144.878 157.720 1.00 88.24 ? 253 LYS D NZ  1 
ATOM   11620 N N   . THR D 1 254 ? 131.628 141.848 158.038 1.00 83.80 ? 254 THR D N   1 
ATOM   11621 C CA  . THR D 1 254 ? 131.483 141.162 156.762 1.00 83.80 ? 254 THR D CA  1 
ATOM   11622 C C   . THR D 1 254 ? 130.054 141.265 156.259 1.00 83.80 ? 254 THR D C   1 
ATOM   11623 O O   . THR D 1 254 ? 129.805 141.717 155.138 1.00 83.80 ? 254 THR D O   1 
ATOM   11624 C CB  . THR D 1 254 ? 131.880 139.699 156.911 1.00 83.80 ? 254 THR D CB  1 
ATOM   11625 O OG1 . THR D 1 254 ? 133.183 139.621 157.495 1.00 83.80 ? 254 THR D OG1 1 
ATOM   11626 C CG2 . THR D 1 254 ? 131.882 139.017 155.565 1.00 83.80 ? 254 THR D CG2 1 
ATOM   11627 N N   . HIS D 1 255 ? 129.097 140.876 157.095 1.00 82.91 ? 255 HIS D N   1 
ATOM   11628 C CA  . HIS D 1 255 ? 127.720 140.744 156.654 1.00 82.91 ? 255 HIS D CA  1 
ATOM   11629 C C   . HIS D 1 255 ? 127.074 142.072 156.294 1.00 82.91 ? 255 HIS D C   1 
ATOM   11630 O O   . HIS D 1 255 ? 125.986 142.068 155.710 1.00 82.91 ? 255 HIS D O   1 
ATOM   11631 C CB  . HIS D 1 255 ? 126.897 140.044 157.729 1.00 82.91 ? 255 HIS D CB  1 
ATOM   11632 C CG  . HIS D 1 255 ? 125.636 139.438 157.209 1.00 82.91 ? 255 HIS D CG  1 
ATOM   11633 N ND1 . HIS D 1 255 ? 124.633 140.191 156.638 1.00 82.91 ? 255 HIS D ND1 1 
ATOM   11634 C CD2 . HIS D 1 255 ? 125.218 138.152 157.157 1.00 82.91 ? 255 HIS D CD2 1 
ATOM   11635 C CE1 . HIS D 1 255 ? 123.647 139.395 156.264 1.00 82.91 ? 255 HIS D CE1 1 
ATOM   11636 N NE2 . HIS D 1 255 ? 123.977 138.153 156.569 1.00 82.91 ? 255 HIS D NE2 1 
ATOM   11637 N N   . GLU D 1 256 ? 127.699 143.199 156.626 1.00 86.34 ? 256 GLU D N   1 
ATOM   11638 C CA  . GLU D 1 256 ? 127.122 144.480 156.234 1.00 86.34 ? 256 GLU D CA  1 
ATOM   11639 C C   . GLU D 1 256 ? 127.447 144.835 154.789 1.00 86.34 ? 256 GLU D C   1 
ATOM   11640 O O   . GLU D 1 256 ? 126.646 145.503 154.127 1.00 86.34 ? 256 GLU D O   1 
ATOM   11641 C CB  . GLU D 1 256 ? 127.606 145.596 157.162 1.00 86.34 ? 256 GLU D CB  1 
ATOM   11642 C CG  . GLU D 1 256 ? 129.071 145.943 157.008 1.00 86.34 ? 256 GLU D CG  1 
ATOM   11643 C CD  . GLU D 1 256 ? 129.538 146.986 158.002 1.00 86.34 ? 256 GLU D CD  1 
ATOM   11644 O OE1 . GLU D 1 256 ? 128.724 147.420 158.842 1.00 86.34 ? 256 GLU D OE1 1 
ATOM   11645 O OE2 . GLU D 1 256 ? 130.722 147.377 157.943 1.00 86.34 ? 256 GLU D OE2 1 
ATOM   11646 N N   . THR D 1 257 ? 128.602 144.401 154.284 1.00 83.99 ? 257 THR D N   1 
ATOM   11647 C CA  . THR D 1 257 ? 129.057 144.754 152.945 1.00 83.99 ? 257 THR D CA  1 
ATOM   11648 C C   . THR D 1 257 ? 128.725 143.691 151.905 1.00 83.99 ? 257 THR D C   1 
ATOM   11649 O O   . THR D 1 257 ? 128.323 144.030 150.790 1.00 83.99 ? 257 THR D O   1 
ATOM   11650 C CB  . THR D 1 257 ? 130.565 145.047 152.964 1.00 83.99 ? 257 THR D CB  1 
ATOM   11651 O OG1 . THR D 1 257 ? 131.007 145.392 151.647 1.00 83.99 ? 257 THR D OG1 1 
ATOM   11652 C CG2 . THR D 1 257 ? 131.358 143.865 153.486 1.00 83.99 ? 257 THR D CG2 1 
ATOM   11653 N N   . MET D 1 258 ? 128.866 142.413 152.242 1.00 80.80 ? 258 MET D N   1 
ATOM   11654 C CA  . MET D 1 258 ? 128.582 141.361 151.278 1.00 80.80 ? 258 MET D CA  1 
ATOM   11655 C C   . MET D 1 258 ? 127.103 141.027 151.259 1.00 80.80 ? 258 MET D C   1 
ATOM   11656 O O   . MET D 1 258 ? 126.392 141.198 152.247 1.00 80.80 ? 258 MET D O   1 
ATOM   11657 C CB  . MET D 1 258 ? 129.382 140.105 151.598 1.00 80.80 ? 258 MET D CB  1 
ATOM   11658 C CG  . MET D 1 258 ? 129.151 139.540 152.979 1.00 80.80 ? 258 MET D CG  1 
ATOM   11659 S SD  . MET D 1 258 ? 127.761 138.416 153.139 1.00 80.80 ? 258 MET D SD  1 
ATOM   11660 C CE  . MET D 1 258 ? 128.468 136.950 152.403 1.00 80.80 ? 258 MET D CE  1 
ATOM   11661 N N   . MET D 1 259 ? 126.638 140.539 150.123 1.00 78.49 ? 259 MET D N   1 
ATOM   11662 C CA  . MET D 1 259 ? 125.281 140.023 150.023 1.00 78.49 ? 259 MET D CA  1 
ATOM   11663 C C   . MET D 1 259 ? 125.384 138.529 150.248 1.00 78.49 ? 259 MET D C   1 
ATOM   11664 O O   . MET D 1 259 ? 125.972 137.815 149.431 1.00 78.49 ? 259 MET D O   1 
ATOM   11665 C CB  . MET D 1 259 ? 124.639 140.329 148.675 1.00 78.49 ? 259 MET D CB  1 
ATOM   11666 C CG  . MET D 1 259 ? 123.175 139.922 148.609 1.00 78.49 ? 259 MET D CG  1 
ATOM   11667 S SD  . MET D 1 259 ? 122.429 140.279 147.011 1.00 78.49 ? 259 MET D SD  1 
ATOM   11668 C CE  . MET D 1 259 ? 122.430 142.067 147.026 1.00 78.49 ? 259 MET D CE  1 
ATOM   11669 N N   . VAL D 1 260 ? 124.834 138.058 151.365 1.00 75.19 ? 260 VAL D N   1 
ATOM   11670 C CA  . VAL D 1 260 ? 125.029 136.664 151.714 1.00 75.19 ? 260 VAL D CA  1 
ATOM   11671 C C   . VAL D 1 260 ? 124.128 135.754 150.896 1.00 75.19 ? 260 VAL D C   1 
ATOM   11672 O O   . VAL D 1 260 ? 124.418 134.562 150.759 1.00 75.19 ? 260 VAL D O   1 
ATOM   11673 C CB  . VAL D 1 260 ? 124.817 136.469 153.225 1.00 75.19 ? 260 VAL D CB  1 
ATOM   11674 C CG1 . VAL D 1 260 ? 123.364 136.633 153.584 1.00 75.19 ? 260 VAL D CG1 1 
ATOM   11675 C CG2 . VAL D 1 260 ? 125.363 135.129 153.679 1.00 75.19 ? 260 VAL D CG2 1 
ATOM   11676 N N   . ASP D 1 261 ? 123.065 136.284 150.309 1.00 75.05 ? 261 ASP D N   1 
ATOM   11677 C CA  . ASP D 1 261 ? 122.126 135.436 149.596 1.00 75.05 ? 261 ASP D CA  1 
ATOM   11678 C C   . ASP D 1 261 ? 122.543 135.125 148.168 1.00 75.05 ? 261 ASP D C   1 
ATOM   11679 O O   . ASP D 1 261 ? 121.883 134.310 147.522 1.00 75.05 ? 261 ASP D O   1 
ATOM   11680 C CB  . ASP D 1 261 ? 120.746 136.075 149.613 1.00 75.05 ? 261 ASP D CB  1 
ATOM   11681 C CG  . ASP D 1 261 ? 120.112 136.021 150.977 1.00 75.05 ? 261 ASP D CG  1 
ATOM   11682 O OD1 . ASP D 1 261 ? 120.845 135.796 151.962 1.00 75.05 ? 261 ASP D OD1 1 
ATOM   11683 O OD2 . ASP D 1 261 ? 118.877 136.182 151.062 1.00 75.05 ? 261 ASP D OD2 1 
ATOM   11684 N N   . ARG D 1 262 ? 123.600 135.736 147.650 1.00 73.34 ? 262 ARG D N   1 
ATOM   11685 C CA  . ARG D 1 262 ? 124.165 135.300 146.376 1.00 73.34 ? 262 ARG D CA  1 
ATOM   11686 C C   . ARG D 1 262 ? 125.340 134.374 146.664 1.00 73.34 ? 262 ARG D C   1 
ATOM   11687 O O   . ARG D 1 262 ? 126.490 134.644 146.330 1.00 73.34 ? 262 ARG D O   1 
ATOM   11688 C CB  . ARG D 1 262 ? 124.581 136.497 145.526 1.00 73.34 ? 262 ARG D CB  1 
ATOM   11689 C CG  . ARG D 1 262 ? 123.466 137.470 145.201 1.00 73.34 ? 262 ARG D CG  1 
ATOM   11690 C CD  . ARG D 1 262 ? 122.525 136.938 144.138 1.00 73.34 ? 262 ARG D CD  1 
ATOM   11691 N NE  . ARG D 1 262 ? 121.425 136.176 144.724 1.00 73.34 ? 262 ARG D NE  1 
ATOM   11692 C CZ  . ARG D 1 262 ? 120.365 135.740 144.050 1.00 73.34 ? 262 ARG D CZ  1 
ATOM   11693 N NH1 . ARG D 1 262 ? 120.249 135.984 142.752 1.00 73.34 ? 262 ARG D NH1 1 
ATOM   11694 N NH2 . ARG D 1 262 ? 119.419 135.054 144.673 1.00 73.34 ? 262 ARG D NH2 1 
ATOM   11695 N N   . SER D 1 263 ? 125.018 133.258 147.308 1.00 66.77 ? 263 SER D N   1 
ATOM   11696 C CA  . SER D 1 263 ? 126.034 132.329 147.767 1.00 66.77 ? 263 SER D CA  1 
ATOM   11697 C C   . SER D 1 263 ? 125.674 130.910 147.361 1.00 66.77 ? 263 SER D C   1 
ATOM   11698 O O   . SER D 1 263 ? 124.498 130.539 147.315 1.00 66.77 ? 263 SER D O   1 
ATOM   11699 C CB  . SER D 1 263 ? 126.206 132.404 149.284 1.00 66.77 ? 263 SER D CB  1 
ATOM   11700 O OG  . SER D 1 263 ? 126.285 133.748 149.710 1.00 66.77 ? 263 SER D OG  1 
ATOM   11701 N N   . TYR D 1 264 ? 126.700 130.117 147.067 1.00 61.41 ? 264 TYR D N   1 
ATOM   11702 C CA  . TYR D 1 264 ? 126.500 128.694 146.868 1.00 61.41 ? 264 TYR D CA  1 
ATOM   11703 C C   . TYR D 1 264 ? 127.741 127.955 147.329 1.00 61.41 ? 264 TYR D C   1 
ATOM   11704 O O   . TYR D 1 264 ? 128.765 128.558 147.646 1.00 61.41 ? 264 TYR D O   1 
ATOM   11705 C CB  . TYR D 1 264 ? 126.170 128.339 145.409 1.00 61.41 ? 264 TYR D CB  1 
ATOM   11706 C CG  . TYR D 1 264 ? 127.224 128.610 144.349 1.00 61.41 ? 264 TYR D CG  1 
ATOM   11707 C CD1 . TYR D 1 264 ? 128.353 127.811 144.239 1.00 61.41 ? 264 TYR D CD1 1 
ATOM   11708 C CD2 . TYR D 1 264 ? 127.087 129.654 143.454 1.00 61.41 ? 264 TYR D CD2 1 
ATOM   11709 C CE1 . TYR D 1 264 ? 129.304 128.043 143.278 1.00 61.41 ? 264 TYR D CE1 1 
ATOM   11710 C CE2 . TYR D 1 264 ? 128.029 129.875 142.476 1.00 61.41 ? 264 TYR D CE2 1 
ATOM   11711 C CZ  . TYR D 1 264 ? 129.140 129.074 142.404 1.00 61.41 ? 264 TYR D CZ  1 
ATOM   11712 O OH  . TYR D 1 264 ? 130.094 129.296 141.442 1.00 61.41 ? 264 TYR D OH  1 
ATOM   11713 N N   . LEU D 1 265 ? 127.641 126.632 147.363 1.00 60.32 ? 265 LEU D N   1 
ATOM   11714 C CA  . LEU D 1 265 ? 128.814 125.784 147.514 1.00 60.32 ? 265 LEU D CA  1 
ATOM   11715 C C   . LEU D 1 265 ? 128.792 124.739 146.417 1.00 60.32 ? 265 LEU D C   1 
ATOM   11716 O O   . LEU D 1 265 ? 127.719 124.334 145.966 1.00 60.32 ? 265 LEU D O   1 
ATOM   11717 C CB  . LEU D 1 265 ? 128.883 125.107 148.880 1.00 60.32 ? 265 LEU D CB  1 
ATOM   11718 C CG  . LEU D 1 265 ? 127.963 123.959 149.282 1.00 60.32 ? 265 LEU D CG  1 
ATOM   11719 C CD1 . LEU D 1 265 ? 128.557 122.616 148.903 1.00 60.32 ? 265 LEU D CD1 1 
ATOM   11720 C CD2 . LEU D 1 265 ? 127.734 123.997 150.766 1.00 60.32 ? 265 LEU D CD2 1 
ATOM   11721 N N   . SER D 1 266 ? 129.966 124.289 146.003 1.00 59.93 ? 266 SER D N   1 
ATOM   11722 C CA  . SER D 1 266 ? 130.077 123.488 144.800 1.00 59.93 ? 266 SER D CA  1 
ATOM   11723 C C   . SER D 1 266 ? 130.983 122.290 145.033 1.00 59.93 ? 266 SER D C   1 
ATOM   11724 O O   . SER D 1 266 ? 131.697 122.204 146.033 1.00 59.93 ? 266 SER D O   1 
ATOM   11725 C CB  . SER D 1 266 ? 130.594 124.336 143.640 1.00 59.93 ? 266 SER D CB  1 
ATOM   11726 O OG  . SER D 1 266 ? 131.881 124.846 143.926 1.00 59.93 ? 266 SER D OG  1 
ATOM   11727 N N   . PHE D 1 267 ? 130.940 121.364 144.080 1.00 53.15 ? 267 PHE D N   1 
ATOM   11728 C CA  . PHE D 1 267 ? 131.655 120.104 144.191 1.00 53.15 ? 267 PHE D CA  1 
ATOM   11729 C C   . PHE D 1 267 ? 131.686 119.446 142.824 1.00 53.15 ? 267 PHE D C   1 
ATOM   11730 O O   . PHE D 1 267 ? 130.843 119.714 141.963 1.00 53.15 ? 267 PHE D O   1 
ATOM   11731 C CB  . PHE D 1 267 ? 130.992 119.169 145.201 1.00 53.15 ? 267 PHE D CB  1 
ATOM   11732 C CG  . PHE D 1 267 ? 129.592 118.794 144.831 1.00 53.15 ? 267 PHE D CG  1 
ATOM   11733 C CD1 . PHE D 1 267 ? 128.532 119.554 145.252 1.00 53.15 ? 267 PHE D CD1 1 
ATOM   11734 C CD2 . PHE D 1 267 ? 129.339 117.696 144.043 1.00 53.15 ? 267 PHE D CD2 1 
ATOM   11735 C CE1 . PHE D 1 267 ? 127.261 119.225 144.906 1.00 53.15 ? 267 PHE D CE1 1 
ATOM   11736 C CE2 . PHE D 1 267 ? 128.063 117.371 143.693 1.00 53.15 ? 267 PHE D CE2 1 
ATOM   11737 C CZ  . PHE D 1 267 ? 127.022 118.136 144.127 1.00 53.15 ? 267 PHE D CZ  1 
ATOM   11738 N N   . ASP D 1 268 ? 132.641 118.546 142.652 1.00 57.40 ? 268 ASP D N   1 
ATOM   11739 C CA  . ASP D 1 268 ? 132.801 117.816 141.409 1.00 57.40 ? 268 ASP D CA  1 
ATOM   11740 C C   . ASP D 1 268 ? 132.144 116.448 141.516 1.00 57.40 ? 268 ASP D C   1 
ATOM   11741 O O   . ASP D 1 268 ? 132.340 115.732 142.501 1.00 57.40 ? 268 ASP D O   1 
ATOM   11742 C CB  . ASP D 1 268 ? 134.278 117.656 141.088 1.00 57.40 ? 268 ASP D CB  1 
ATOM   11743 C CG  . ASP D 1 268 ? 134.973 118.974 140.961 1.00 57.40 ? 268 ASP D CG  1 
ATOM   11744 O OD1 . ASP D 1 268 ? 134.309 119.961 140.604 1.00 57.40 ? 268 ASP D OD1 1 
ATOM   11745 O OD2 . ASP D 1 268 ? 136.182 119.032 141.233 1.00 57.40 ? 268 ASP D OD2 1 
ATOM   11746 N N   . CYS D 1 269 ? 131.374 116.086 140.494 1.00 55.67 ? 269 CYS D N   1 
ATOM   11747 C CA  . CYS D 1 269 ? 130.781 114.753 140.407 1.00 55.67 ? 269 CYS D CA  1 
ATOM   11748 C C   . CYS D 1 269 ? 131.878 113.775 140.011 1.00 55.67 ? 269 CYS D C   1 
ATOM   11749 O O   . CYS D 1 269 ? 132.069 113.452 138.841 1.00 55.67 ? 269 CYS D O   1 
ATOM   11750 C CB  . CYS D 1 269 ? 129.625 114.741 139.421 1.00 55.67 ? 269 CYS D CB  1 
ATOM   11751 S SG  . CYS D 1 269 ? 128.302 115.872 139.862 1.00 55.67 ? 269 CYS D SG  1 
ATOM   11752 N N   . LEU D 1 270 ? 132.614 113.305 141.010 1.00 61.65 ? 270 LEU D N   1 
ATOM   11753 C CA  . LEU D 1 270 ? 133.770 112.454 140.798 1.00 61.65 ? 270 LEU D CA  1 
ATOM   11754 C C   . LEU D 1 270 ? 133.936 111.556 142.013 1.00 61.65 ? 270 LEU D C   1 
ATOM   11755 O O   . LEU D 1 270 ? 133.040 111.447 142.854 1.00 61.65 ? 270 LEU D O   1 
ATOM   11756 C CB  . LEU D 1 270 ? 135.026 113.295 140.556 1.00 61.65 ? 270 LEU D CB  1 
ATOM   11757 C CG  . LEU D 1 270 ? 135.293 113.787 139.139 1.00 61.65 ? 270 LEU D CG  1 
ATOM   11758 C CD1 . LEU D 1 270 ? 136.620 114.511 139.094 1.00 61.65 ? 270 LEU D CD1 1 
ATOM   11759 C CD2 . LEU D 1 270 ? 135.280 112.627 138.170 1.00 61.65 ? 270 LEU D CD2 1 
ATOM   11760 N N   . ASP D 1 271 ? 135.085 110.905 142.096 1.00 68.83 ? 271 ASP D N   1 
ATOM   11761 C CA  . ASP D 1 271 ? 135.459 110.125 143.265 1.00 68.83 ? 271 ASP D CA  1 
ATOM   11762 C C   . ASP D 1 271 ? 135.617 111.069 144.446 1.00 68.83 ? 271 ASP D C   1 
ATOM   11763 O O   . ASP D 1 271 ? 136.567 111.860 144.477 1.00 68.83 ? 271 ASP D O   1 
ATOM   11764 C CB  . ASP D 1 271 ? 136.755 109.358 143.003 1.00 68.83 ? 271 ASP D CB  1 
ATOM   11765 C CG  . ASP D 1 271 ? 137.012 108.279 144.029 1.00 68.83 ? 271 ASP D CG  1 
ATOM   11766 O OD1 . ASP D 1 271 ? 136.291 108.233 145.043 1.00 68.83 ? 271 ASP D OD1 1 
ATOM   11767 O OD2 . ASP D 1 271 ? 137.937 107.469 143.820 1.00 68.83 ? 271 ASP D OD2 1 
ATOM   11768 N N   . PRO D 1 272 ? 134.719 111.020 145.434 1.00 68.54 ? 272 PRO D N   1 
ATOM   11769 C CA  . PRO D 1 272 ? 134.767 112.009 146.521 1.00 68.54 ? 272 PRO D CA  1 
ATOM   11770 C C   . PRO D 1 272 ? 136.087 112.047 147.246 1.00 68.54 ? 272 PRO D C   1 
ATOM   11771 O O   . PRO D 1 272 ? 136.323 112.986 148.009 1.00 68.54 ? 272 PRO D O   1 
ATOM   11772 C CB  . PRO D 1 272 ? 133.628 111.574 147.450 1.00 68.54 ? 272 PRO D CB  1 
ATOM   11773 C CG  . PRO D 1 272 ? 133.336 110.187 147.077 1.00 68.54 ? 272 PRO D CG  1 
ATOM   11774 C CD  . PRO D 1 272 ? 133.631 110.055 145.625 1.00 68.54 ? 272 PRO D CD  1 
ATOM   11775 N N   . ALA D 1 273 ? 136.960 111.066 147.029 1.00 70.95 ? 273 ALA D N   1 
ATOM   11776 C CA  . ALA D 1 273 ? 138.340 111.201 147.466 1.00 70.95 ? 273 ALA D CA  1 
ATOM   11777 C C   . ALA D 1 273 ? 139.137 112.125 146.553 1.00 70.95 ? 273 ALA D C   1 
ATOM   11778 O O   . ALA D 1 273 ? 140.300 112.416 146.847 1.00 70.95 ? 273 ALA D O   1 
ATOM   11779 C CB  . ALA D 1 273 ? 139.002 109.827 147.537 1.00 70.95 ? 273 ALA D CB  1 
ATOM   11780 N N   . LYS D 1 274 ? 138.541 112.592 145.458 1.00 70.98 ? 274 LYS D N   1 
ATOM   11781 C CA  . LYS D 1 274 ? 139.218 113.496 144.543 1.00 70.98 ? 274 LYS D CA  1 
ATOM   11782 C C   . LYS D 1 274 ? 138.522 114.839 144.402 1.00 70.98 ? 274 LYS D C   1 
ATOM   11783 O O   . LYS D 1 274 ? 139.165 115.811 143.991 1.00 70.98 ? 274 LYS D O   1 
ATOM   11784 C CB  . LYS D 1 274 ? 139.337 112.853 143.160 1.00 70.98 ? 274 LYS D CB  1 
ATOM   11785 C CG  . LYS D 1 274 ? 139.918 111.462 143.181 1.00 70.98 ? 274 LYS D CG  1 
ATOM   11786 C CD  . LYS D 1 274 ? 141.347 111.485 143.670 1.00 70.98 ? 274 LYS D CD  1 
ATOM   11787 C CE  . LYS D 1 274 ? 141.886 110.079 143.859 1.00 70.98 ? 274 LYS D CE  1 
ATOM   11788 N NZ  . LYS D 1 274 ? 141.305 109.416 145.057 1.00 70.98 ? 274 LYS D NZ  1 
ATOM   11789 N N   . SER D 1 275 ? 137.235 114.920 144.730 1.00 67.81 ? 275 SER D N   1 
ATOM   11790 C CA  . SER D 1 275 ? 136.493 116.158 144.570 1.00 67.81 ? 275 SER D CA  1 
ATOM   11791 C C   . SER D 1 275 ? 136.943 117.192 145.600 1.00 67.81 ? 275 SER D C   1 
ATOM   11792 O O   . SER D 1 275 ? 137.794 116.943 146.458 1.00 67.81 ? 275 SER D O   1 
ATOM   11793 C CB  . SER D 1 275 ? 134.998 115.901 144.693 1.00 67.81 ? 275 SER D CB  1 
ATOM   11794 O OG  . SER D 1 275 ? 134.537 115.033 143.680 1.00 67.81 ? 275 SER D OG  1 
ATOM   11795 N N   . ARG D 1 276 ? 136.355 118.378 145.501 1.00 66.14 ? 276 ARG D N   1 
ATOM   11796 C CA  . ARG D 1 276 ? 136.614 119.482 146.407 1.00 66.14 ? 276 ARG D CA  1 
ATOM   11797 C C   . ARG D 1 276 ? 135.279 120.069 146.829 1.00 66.14 ? 276 ARG D C   1 
ATOM   11798 O O   . ARG D 1 276 ? 134.231 119.725 146.280 1.00 66.14 ? 276 ARG D O   1 
ATOM   11799 C CB  . ARG D 1 276 ? 137.493 120.548 145.744 1.00 66.14 ? 276 ARG D CB  1 
ATOM   11800 C CG  . ARG D 1 276 ? 138.877 120.053 145.354 1.00 66.14 ? 276 ARG D CG  1 
ATOM   11801 C CD  . ARG D 1 276 ? 138.910 119.526 143.932 1.00 66.14 ? 276 ARG D CD  1 
ATOM   11802 N NE  . ARG D 1 276 ? 138.532 120.527 142.939 1.00 66.14 ? 276 ARG D NE  1 
ATOM   11803 C CZ  . ARG D 1 276 ? 139.387 121.342 142.329 1.00 66.14 ? 276 ARG D CZ  1 
ATOM   11804 N NH1 . ARG D 1 276 ? 140.680 121.284 142.612 1.00 66.14 ? 276 ARG D NH1 1 
ATOM   11805 N NH2 . ARG D 1 276 ? 138.944 122.220 141.440 1.00 66.14 ? 276 ARG D NH2 1 
ATOM   11806 N N   . ILE D 1 277 ? 135.303 120.961 147.811 1.00 66.25 ? 277 ILE D N   1 
ATOM   11807 C CA  . ILE D 1 277 ? 134.097 121.689 148.184 1.00 66.25 ? 277 ILE D CA  1 
ATOM   11808 C C   . ILE D 1 277 ? 134.431 123.171 148.190 1.00 66.25 ? 277 ILE D C   1 
ATOM   11809 O O   . ILE D 1 277 ? 135.230 123.624 149.013 1.00 66.25 ? 277 ILE D O   1 
ATOM   11810 C CB  . ILE D 1 277 ? 133.540 121.249 149.545 1.00 66.25 ? 277 ILE D CB  1 
ATOM   11811 C CG1 . ILE D 1 277 ? 133.077 119.798 149.497 1.00 66.25 ? 277 ILE D CG1 1 
ATOM   11812 C CG2 . ILE D 1 277 ? 132.356 122.114 149.929 1.00 66.25 ? 277 ILE D CG2 1 
ATOM   11813 C CD1 . ILE D 1 277 ? 131.692 119.639 148.967 1.00 66.25 ? 277 ILE D CD1 1 
ATOM   11814 N N   . LYS D 1 278 ? 133.838 123.918 147.268 1.00 65.76 ? 278 LYS D N   1 
ATOM   11815 C CA  . LYS D 1 278 ? 134.062 125.349 147.148 1.00 65.76 ? 278 LYS D CA  1 
ATOM   11816 C C   . LYS D 1 278 ? 132.838 126.087 147.655 1.00 65.76 ? 278 LYS D C   1 
ATOM   11817 O O   . LYS D 1 278 ? 131.725 125.810 147.208 1.00 65.76 ? 278 LYS D O   1 
ATOM   11818 C CB  . LYS D 1 278 ? 134.335 125.748 145.698 1.00 65.76 ? 278 LYS D CB  1 
ATOM   11819 C CG  . LYS D 1 278 ? 135.416 124.944 145.014 1.00 65.76 ? 278 LYS D CG  1 
ATOM   11820 C CD  . LYS D 1 278 ? 135.794 125.534 143.662 1.00 65.76 ? 278 LYS D CD  1 
ATOM   11821 C CE  . LYS D 1 278 ? 134.665 125.425 142.649 1.00 65.76 ? 278 LYS D CE  1 
ATOM   11822 N NZ  . LYS D 1 278 ? 135.043 126.023 141.340 1.00 65.76 ? 278 LYS D NZ  1 
ATOM   11823 N N   . ILE D 1 279 ? 133.044 127.015 148.582 1.00 66.39 ? 279 ILE D N   1 
ATOM   11824 C CA  . ILE D 1 279 ? 132.021 127.972 148.983 1.00 66.39 ? 279 ILE D CA  1 
ATOM   11825 C C   . ILE D 1 279 ? 132.201 129.223 148.139 1.00 66.39 ? 279 ILE D C   1 
ATOM   11826 O O   . ILE D 1 279 ? 133.291 129.499 147.640 1.00 66.39 ? 279 ILE D O   1 
ATOM   11827 C CB  . ILE D 1 279 ? 132.085 128.297 150.489 1.00 66.39 ? 279 ILE D CB  1 
ATOM   11828 C CG1 . ILE D 1 279 ? 132.298 127.030 151.313 1.00 66.39 ? 279 ILE D CG1 1 
ATOM   11829 C CG2 . ILE D 1 279 ? 130.796 128.936 150.935 1.00 66.39 ? 279 ILE D CG2 1 
ATOM   11830 C CD1 . ILE D 1 279 ? 131.073 126.159 151.418 1.00 66.39 ? 279 ILE D CD1 1 
ATOM   11831 N N   . TYR D 1 280 ? 131.129 129.994 147.983 1.00 67.78 ? 280 TYR D N   1 
ATOM   11832 C CA  . TYR D 1 280 ? 131.074 131.054 146.986 1.00 67.78 ? 280 TYR D CA  1 
ATOM   11833 C C   . TYR D 1 280 ? 130.093 132.127 147.427 1.00 67.78 ? 280 TYR D C   1 
ATOM   11834 O O   . TYR D 1 280 ? 128.961 131.796 147.777 1.00 67.78 ? 280 TYR D O   1 
ATOM   11835 C CB  . TYR D 1 280 ? 130.619 130.481 145.653 1.00 67.78 ? 280 TYR D CB  1 
ATOM   11836 C CG  . TYR D 1 280 ? 130.430 131.511 144.587 1.00 67.78 ? 280 TYR D CG  1 
ATOM   11837 C CD1 . TYR D 1 280 ? 131.482 131.904 143.782 1.00 67.78 ? 280 TYR D CD1 1 
ATOM   11838 C CD2 . TYR D 1 280 ? 129.205 132.130 144.416 1.00 67.78 ? 280 TYR D CD2 1 
ATOM   11839 C CE1 . TYR D 1 280 ? 131.304 132.854 142.808 1.00 67.78 ? 280 TYR D CE1 1 
ATOM   11840 C CE2 . TYR D 1 280 ? 129.018 133.075 143.455 1.00 67.78 ? 280 TYR D CE2 1 
ATOM   11841 C CZ  . TYR D 1 280 ? 130.066 133.438 142.656 1.00 67.78 ? 280 TYR D CZ  1 
ATOM   11842 O OH  . TYR D 1 280 ? 129.862 134.394 141.700 1.00 67.78 ? 280 TYR D OH  1 
ATOM   11843 N N   . THR D 1 281 ? 130.498 133.400 147.367 1.00 70.95 ? 281 THR D N   1 
ATOM   11844 C CA  . THR D 1 281 ? 129.601 134.502 147.712 1.00 70.95 ? 281 THR D CA  1 
ATOM   11845 C C   . THR D 1 281 ? 130.046 135.771 146.980 1.00 70.95 ? 281 THR D C   1 
ATOM   11846 O O   . THR D 1 281 ? 130.979 135.746 146.175 1.00 70.95 ? 281 THR D O   1 
ATOM   11847 C CB  . THR D 1 281 ? 129.533 134.691 149.230 1.00 70.95 ? 281 THR D CB  1 
ATOM   11848 O OG1 . THR D 1 281 ? 128.344 135.410 149.572 1.00 70.95 ? 281 THR D OG1 1 
ATOM   11849 C CG2 . THR D 1 281 ? 130.732 135.445 149.727 1.00 70.95 ? 281 THR D CG2 1 
ATOM   11850 N N   . GLU D 1 282 ? 129.349 136.887 147.251 1.00 75.28 ? 282 GLU D N   1 
ATOM   11851 C CA  . GLU D 1 282 ? 129.455 138.115 146.463 1.00 75.28 ? 282 GLU D CA  1 
ATOM   11852 C C   . GLU D 1 282 ? 129.476 139.355 147.350 1.00 75.28 ? 282 GLU D C   1 
ATOM   11853 O O   . GLU D 1 282 ? 128.749 139.430 148.348 1.00 75.28 ? 282 GLU D O   1 
ATOM   11854 C CB  . GLU D 1 282 ? 128.288 138.237 145.474 1.00 75.28 ? 282 GLU D CB  1 
ATOM   11855 C CG  . GLU D 1 282 ? 128.317 137.224 144.346 1.00 75.28 ? 282 GLU D CG  1 
ATOM   11856 C CD  . GLU D 1 282 ? 127.246 137.477 143.307 1.00 75.28 ? 282 GLU D CD  1 
ATOM   11857 O OE1 . GLU D 1 282 ? 126.391 138.354 143.535 1.00 75.28 ? 282 GLU D OE1 1 
ATOM   11858 O OE2 . GLU D 1 282 ? 127.260 136.800 142.260 1.00 75.28 ? 282 GLU D OE2 1 
ATOM   11859 N N   . ALA D 1 283 ? 130.280 140.348 146.954 1.00 77.38 ? 283 ALA D N   1 
ATOM   11860 C CA  . ALA D 1 283 ? 130.475 141.556 147.744 1.00 77.38 ? 283 ALA D CA  1 
ATOM   11861 C C   . ALA D 1 283 ? 130.436 142.798 146.863 1.00 77.38 ? 283 ALA D C   1 
ATOM   11862 O O   . ALA D 1 283 ? 130.834 142.770 145.694 1.00 77.38 ? 283 ALA D O   1 
ATOM   11863 C CB  . ALA D 1 283 ? 131.804 141.523 148.501 1.00 77.38 ? 283 ALA D CB  1 
ATOM   11864 N N   . LYS D 1 284 ? 129.946 143.893 147.445 1.00 78.05 ? 284 LYS D N   1 
ATOM   11865 C CA  . LYS D 1 284 ? 129.942 145.222 146.836 1.00 78.05 ? 284 LYS D CA  1 
ATOM   11866 C C   . LYS D 1 284 ? 130.875 146.079 147.675 1.00 78.05 ? 284 LYS D C   1 
ATOM   11867 O O   . LYS D 1 284 ? 130.457 146.648 148.686 1.00 78.05 ? 284 LYS D O   1 
ATOM   11868 C CB  . LYS D 1 284 ? 128.543 145.822 146.806 1.00 78.05 ? 284 LYS D CB  1 
ATOM   11869 C CG  . LYS D 1 284 ? 127.730 145.474 145.588 1.00 78.05 ? 284 LYS D CG  1 
ATOM   11870 C CD  . LYS D 1 284 ? 126.295 145.910 145.778 1.00 78.05 ? 284 LYS D CD  1 
ATOM   11871 C CE  . LYS D 1 284 ? 125.422 145.411 144.652 1.00 78.05 ? 284 LYS D CE  1 
ATOM   11872 N NZ  . LYS D 1 284 ? 124.011 145.272 145.091 1.00 78.05 ? 284 LYS D NZ  1 
ATOM   11873 N N   . VAL D 1 285 ? 132.128 146.186 147.264 1.00 81.43 ? 285 VAL D N   1 
ATOM   11874 C CA  . VAL D 1 285 ? 133.156 146.754 148.122 1.00 81.43 ? 285 VAL D CA  1 
ATOM   11875 C C   . VAL D 1 285 ? 133.596 148.111 147.598 1.00 81.43 ? 285 VAL D C   1 
ATOM   11876 O O   . VAL D 1 285 ? 133.560 148.390 146.396 1.00 81.43 ? 285 VAL D O   1 
ATOM   11877 C CB  . VAL D 1 285 ? 134.359 145.805 148.260 1.00 81.43 ? 285 VAL D CB  1 
ATOM   11878 C CG1 . VAL D 1 285 ? 133.912 144.502 148.874 1.00 81.43 ? 285 VAL D CG1 1 
ATOM   11879 C CG2 . VAL D 1 285 ? 135.002 145.566 146.915 1.00 81.43 ? 285 VAL D CG2 1 
ATOM   11880 N N   . LYS D 1 286 ? 134.027 148.958 148.527 1.00 81.30 ? 286 LYS D N   1 
ATOM   11881 C CA  . LYS D 1 286 ? 134.433 150.327 148.248 1.00 81.30 ? 286 LYS D CA  1 
ATOM   11882 C C   . LYS D 1 286 ? 135.911 150.463 147.928 1.00 81.30 ? 286 LYS D C   1 
ATOM   11883 O O   . LYS D 1 286 ? 136.266 151.042 146.900 1.00 81.30 ? 286 LYS D O   1 
ATOM   11884 C CB  . LYS D 1 286 ? 134.100 151.220 149.442 1.00 81.30 ? 286 LYS D CB  1 
ATOM   11885 C CG  . LYS D 1 286 ? 134.578 152.638 149.290 1.00 81.30 ? 286 LYS D CG  1 
ATOM   11886 C CD  . LYS D 1 286 ? 133.838 153.353 148.183 1.00 81.30 ? 286 LYS D CD  1 
ATOM   11887 C CE  . LYS D 1 286 ? 134.232 154.816 148.135 1.00 81.30 ? 286 LYS D CE  1 
ATOM   11888 N NZ  . LYS D 1 286 ? 135.665 154.985 147.763 1.00 81.30 ? 286 LYS D NZ  1 
ATOM   11889 N N   . THR D 1 287 ? 136.781 149.955 148.786 1.00 83.59 ? 287 THR D N   1 
ATOM   11890 C CA  . THR D 1 287 ? 138.214 150.003 148.562 1.00 83.59 ? 287 THR D CA  1 
ATOM   11891 C C   . THR D 1 287 ? 138.740 148.591 148.365 1.00 83.59 ? 287 THR D C   1 
ATOM   11892 O O   . THR D 1 287 ? 138.105 147.614 148.767 1.00 83.59 ? 287 THR D O   1 
ATOM   11893 C CB  . THR D 1 287 ? 138.948 150.659 149.736 1.00 83.59 ? 287 THR D CB  1 
ATOM   11894 O OG1 . THR D 1 287 ? 139.175 149.686 150.762 1.00 83.59 ? 287 THR D OG1 1 
ATOM   11895 C CG2 . THR D 1 287 ? 138.122 151.794 150.307 1.00 83.59 ? 287 THR D CG2 1 
ATOM   11896 N N   . LEU D 1 288 ? 139.904 148.486 147.727 1.00 83.50 ? 288 LEU D N   1 
ATOM   11897 C CA  . LEU D 1 288 ? 140.542 147.181 147.623 1.00 83.50 ? 288 LEU D CA  1 
ATOM   11898 C C   . LEU D 1 288 ? 141.002 146.701 148.991 1.00 83.50 ? 288 LEU D C   1 
ATOM   11899 O O   . LEU D 1 288 ? 140.932 145.503 149.296 1.00 83.50 ? 288 LEU D O   1 
ATOM   11900 C CB  . LEU D 1 288 ? 141.705 147.241 146.634 1.00 83.50 ? 288 LEU D CB  1 
ATOM   11901 C CG  . LEU D 1 288 ? 142.955 148.037 146.997 1.00 83.50 ? 288 LEU D CG  1 
ATOM   11902 C CD1 . LEU D 1 288 ? 144.003 147.130 147.604 1.00 83.50 ? 288 LEU D CD1 1 
ATOM   11903 C CD2 . LEU D 1 288 ? 143.502 148.741 145.777 1.00 83.50 ? 288 LEU D CD2 1 
ATOM   11904 N N   . GLU D 1 289 ? 141.465 147.626 149.831 1.00 85.53 ? 289 GLU D N   1 
ATOM   11905 C CA  . GLU D 1 289 ? 141.821 147.277 151.198 1.00 85.53 ? 289 GLU D CA  1 
ATOM   11906 C C   . GLU D 1 289 ? 140.676 146.546 151.885 1.00 85.53 ? 289 GLU D C   1 
ATOM   11907 O O   . GLU D 1 289 ? 140.857 145.451 152.428 1.00 85.53 ? 289 GLU D O   1 
ATOM   11908 C CB  . GLU D 1 289 ? 142.199 148.539 151.971 1.00 85.53 ? 289 GLU D CB  1 
ATOM   11909 C CG  . GLU D 1 289 ? 142.254 148.353 153.476 1.00 85.53 ? 289 GLU D CG  1 
ATOM   11910 C CD  . GLU D 1 289 ? 140.914 148.585 154.143 1.00 85.53 ? 289 GLU D CD  1 
ATOM   11911 O OE1 . GLU D 1 289 ? 140.039 149.212 153.514 1.00 85.53 ? 289 GLU D OE1 1 
ATOM   11912 O OE2 . GLU D 1 289 ? 140.730 148.126 155.288 1.00 85.53 ? 289 GLU D OE2 1 
ATOM   11913 N N   . GLU D 1 290 ? 139.479 147.135 151.856 1.00 84.79 ? 290 GLU D N   1 
ATOM   11914 C CA  . GLU D 1 290 ? 138.350 146.525 152.543 1.00 84.79 ? 290 GLU D CA  1 
ATOM   11915 C C   . GLU D 1 290 ? 137.957 145.217 151.883 1.00 84.79 ? 290 GLU D C   1 
ATOM   11916 O O   . GLU D 1 290 ? 137.314 144.369 152.507 1.00 84.79 ? 290 GLU D O   1 
ATOM   11917 C CB  . GLU D 1 290 ? 137.161 147.479 152.567 1.00 84.79 ? 290 GLU D CB  1 
ATOM   11918 C CG  . GLU D 1 290 ? 136.184 147.270 151.434 1.00 84.79 ? 290 GLU D CG  1 
ATOM   11919 C CD  . GLU D 1 290 ? 135.103 148.322 151.411 1.00 84.79 ? 290 GLU D CD  1 
ATOM   11920 O OE1 . GLU D 1 290 ? 135.290 149.376 152.051 1.00 84.79 ? 290 GLU D OE1 1 
ATOM   11921 O OE2 . GLU D 1 290 ? 134.061 148.093 150.765 1.00 84.79 ? 290 GLU D OE2 1 
ATOM   11922 N N   . ALA D 1 291 ? 138.326 145.037 150.614 1.00 82.96 ? 291 ALA D N   1 
ATOM   11923 C CA  . ALA D 1 291 ? 138.055 143.777 149.938 1.00 82.96 ? 291 ALA D CA  1 
ATOM   11924 C C   . ALA D 1 291 ? 139.026 142.685 150.345 1.00 82.96 ? 291 ALA D C   1 
ATOM   11925 O O   . ALA D 1 291 ? 138.682 141.506 150.240 1.00 82.96 ? 291 ALA D O   1 
ATOM   11926 C CB  . ALA D 1 291 ? 138.094 143.958 148.421 1.00 82.96 ? 291 ALA D CB  1 
ATOM   11927 N N   . TYR D 1 292 ? 140.221 143.048 150.813 1.00 81.08 ? 292 TYR D N   1 
ATOM   11928 C CA  . TYR D 1 292 ? 141.191 142.045 151.241 1.00 81.08 ? 292 TYR D CA  1 
ATOM   11929 C C   . TYR D 1 292 ? 140.610 141.057 152.239 1.00 81.08 ? 292 TYR D C   1 
ATOM   11930 O O   . TYR D 1 292 ? 141.131 139.943 152.374 1.00 81.08 ? 292 TYR D O   1 
ATOM   11931 C CB  . TYR D 1 292 ? 142.407 142.726 151.856 1.00 81.08 ? 292 TYR D CB  1 
ATOM   11932 C CG  . TYR D 1 292 ? 143.530 141.781 152.189 1.00 81.08 ? 292 TYR D CG  1 
ATOM   11933 C CD1 . TYR D 1 292 ? 143.847 140.727 151.348 1.00 81.08 ? 292 TYR D CD1 1 
ATOM   11934 C CD2 . TYR D 1 292 ? 144.283 141.948 153.342 1.00 81.08 ? 292 TYR D CD2 1 
ATOM   11935 C CE1 . TYR D 1 292 ? 144.875 139.864 151.648 1.00 81.08 ? 292 TYR D CE1 1 
ATOM   11936 C CE2 . TYR D 1 292 ? 145.315 141.090 153.649 1.00 81.08 ? 292 TYR D CE2 1 
ATOM   11937 C CZ  . TYR D 1 292 ? 145.607 140.052 152.797 1.00 81.08 ? 292 TYR D CZ  1 
ATOM   11938 O OH  . TYR D 1 292 ? 146.634 139.194 153.098 1.00 81.08 ? 292 TYR D OH  1 
ATOM   11939 N N   . SER D 1 293 ? 139.535 141.429 152.931 1.00 78.54 ? 293 SER D N   1 
ATOM   11940 C CA  . SER D 1 293 ? 138.932 140.526 153.901 1.00 78.54 ? 293 SER D CA  1 
ATOM   11941 C C   . SER D 1 293 ? 138.451 139.244 153.233 1.00 78.54 ? 293 SER D C   1 
ATOM   11942 O O   . SER D 1 293 ? 138.845 138.141 153.627 1.00 78.54 ? 293 SER D O   1 
ATOM   11943 C CB  . SER D 1 293 ? 137.784 141.228 154.622 1.00 78.54 ? 293 SER D CB  1 
ATOM   11944 O OG  . SER D 1 293 ? 136.596 141.175 153.859 1.00 78.54 ? 293 SER D OG  1 
ATOM   11945 N N   . PHE D 1 294 ? 137.608 139.371 152.206 1.00 77.23 ? 294 PHE D N   1 
ATOM   11946 C CA  . PHE D 1 294 ? 137.056 138.195 151.538 1.00 77.23 ? 294 PHE D CA  1 
ATOM   11947 C C   . PHE D 1 294 ? 138.151 137.297 150.994 1.00 77.23 ? 294 PHE D C   1 
ATOM   11948 O O   . PHE D 1 294 ? 138.060 136.069 151.083 1.00 77.23 ? 294 PHE D O   1 
ATOM   11949 C CB  . PHE D 1 294 ? 136.128 138.621 150.411 1.00 77.23 ? 294 PHE D CB  1 
ATOM   11950 C CG  . PHE D 1 294 ? 134.909 139.315 150.883 1.00 77.23 ? 294 PHE D CG  1 
ATOM   11951 C CD1 . PHE D 1 294 ? 134.971 140.625 151.305 1.00 77.23 ? 294 PHE D CD1 1 
ATOM   11952 C CD2 . PHE D 1 294 ? 133.705 138.657 150.919 1.00 77.23 ? 294 PHE D CD2 1 
ATOM   11953 C CE1 . PHE D 1 294 ? 133.855 141.265 151.748 1.00 77.23 ? 294 PHE D CE1 1 
ATOM   11954 C CE2 . PHE D 1 294 ? 132.588 139.292 151.360 1.00 77.23 ? 294 PHE D CE2 1 
ATOM   11955 C CZ  . PHE D 1 294 ? 132.661 140.600 151.776 1.00 77.23 ? 294 PHE D CZ  1 
ATOM   11956 N N   . TRP D 1 295 ? 139.185 137.890 150.411 1.00 75.31 ? 295 TRP D N   1 
ATOM   11957 C CA  . TRP D 1 295 ? 140.340 137.108 150.004 1.00 75.31 ? 295 TRP D CA  1 
ATOM   11958 C C   . TRP D 1 295 ? 140.974 136.393 151.185 1.00 75.31 ? 295 TRP D C   1 
ATOM   11959 O O   . TRP D 1 295 ? 141.504 135.289 151.029 1.00 75.31 ? 295 TRP D O   1 
ATOM   11960 C CB  . TRP D 1 295 ? 141.362 138.014 149.338 1.00 75.31 ? 295 TRP D CB  1 
ATOM   11961 C CG  . TRP D 1 295 ? 142.471 137.283 148.722 1.00 75.31 ? 295 TRP D CG  1 
ATOM   11962 C CD1 . TRP D 1 295 ? 143.715 137.106 149.229 1.00 75.31 ? 295 TRP D CD1 1 
ATOM   11963 C CD2 . TRP D 1 295 ? 142.448 136.625 147.467 1.00 75.31 ? 295 TRP D CD2 1 
ATOM   11964 N NE1 . TRP D 1 295 ? 144.476 136.372 148.366 1.00 75.31 ? 295 TRP D NE1 1 
ATOM   11965 C CE2 . TRP D 1 295 ? 143.717 136.065 147.270 1.00 75.31 ? 295 TRP D CE2 1 
ATOM   11966 C CE3 . TRP D 1 295 ? 141.474 136.454 146.483 1.00 75.31 ? 295 TRP D CE3 1 
ATOM   11967 C CZ2 . TRP D 1 295 ? 144.036 135.343 146.132 1.00 75.31 ? 295 TRP D CZ2 1 
ATOM   11968 C CZ3 . TRP D 1 295 ? 141.791 135.744 145.361 1.00 75.31 ? 295 TRP D CZ3 1 
ATOM   11969 C CH2 . TRP D 1 295 ? 143.059 135.195 145.190 1.00 75.31 ? 295 TRP D CH2 1 
ATOM   11970 N N   . SER D 1 296 ? 140.929 136.999 152.372 1.00 78.47 ? 296 SER D N   1 
ATOM   11971 C CA  . SER D 1 296 ? 141.667 136.496 153.520 1.00 78.47 ? 296 SER D CA  1 
ATOM   11972 C C   . SER D 1 296 ? 140.775 135.969 154.634 1.00 78.47 ? 296 SER D C   1 
ATOM   11973 O O   . SER D 1 296 ? 141.294 135.551 155.673 1.00 78.47 ? 296 SER D O   1 
ATOM   11974 C CB  . SER D 1 296 ? 142.574 137.594 154.070 1.00 78.47 ? 296 SER D CB  1 
ATOM   11975 O OG  . SER D 1 296 ? 141.810 138.739 154.397 1.00 78.47 ? 296 SER D OG  1 
ATOM   11976 N N   . LEU D 1 297 ? 139.456 135.971 154.451 1.00 77.15 ? 297 LEU D N   1 
ATOM   11977 C CA  . LEU D 1 297 ? 138.526 135.564 155.504 1.00 77.15 ? 297 LEU D CA  1 
ATOM   11978 C C   . LEU D 1 297 ? 138.753 136.369 156.778 1.00 77.15 ? 297 LEU D C   1 
ATOM   11979 O O   . LEU D 1 297 ? 138.655 135.851 157.890 1.00 77.15 ? 297 LEU D O   1 
ATOM   11980 C CB  . LEU D 1 297 ? 138.627 134.070 155.798 1.00 77.15 ? 297 LEU D CB  1 
ATOM   11981 C CG  . LEU D 1 297 ? 138.193 133.114 154.700 1.00 77.15 ? 297 LEU D CG  1 
ATOM   11982 C CD1 . LEU D 1 297 ? 138.264 131.718 155.228 1.00 77.15 ? 297 LEU D CD1 1 
ATOM   11983 C CD2 . LEU D 1 297 ? 136.791 133.433 154.272 1.00 77.15 ? 297 LEU D CD2 1 
ATOM   11984 N N   . GLY D 1 298 ? 139.051 137.652 156.619 1.00 79.49 ? 298 GLY D N   1 
ATOM   11985 C CA  . GLY D 1 298 ? 139.285 138.514 157.754 1.00 79.49 ? 298 GLY D CA  1 
ATOM   11986 C C   . GLY D 1 298 ? 140.625 138.336 158.421 1.00 79.49 ? 298 GLY D C   1 
ATOM   11987 O O   . GLY D 1 298 ? 140.748 138.636 159.613 1.00 79.49 ? 298 GLY D O   1 
ATOM   11988 N N   . GLY D 1 299 ? 141.630 137.858 157.701 1.00 81.33 ? 299 GLY D N   1 
ATOM   11989 C CA  . GLY D 1 299 ? 142.938 137.626 158.266 1.00 81.33 ? 299 GLY D CA  1 
ATOM   11990 C C   . GLY D 1 299 ? 143.182 136.204 158.711 1.00 81.33 ? 299 GLY D C   1 
ATOM   11991 O O   . GLY D 1 299 ? 144.344 135.807 158.851 1.00 81.33 ? 299 GLY D O   1 
ATOM   11992 N N   . ARG D 1 300 ? 142.124 135.425 158.931 1.00 80.53 ? 300 ARG D N   1 
ATOM   11993 C CA  . ARG D 1 300 ? 142.310 134.039 159.339 1.00 80.53 ? 300 ARG D CA  1 
ATOM   11994 C C   . ARG D 1 300 ? 143.022 133.241 158.260 1.00 80.53 ? 300 ARG D C   1 
ATOM   11995 O O   . ARG D 1 300 ? 144.022 132.568 158.533 1.00 80.53 ? 300 ARG D O   1 
ATOM   11996 C CB  . ARG D 1 300 ? 140.962 133.409 159.672 1.00 80.53 ? 300 ARG D CB  1 
ATOM   11997 C CG  . ARG D 1 300 ? 140.214 134.143 160.752 1.00 80.53 ? 300 ARG D CG  1 
ATOM   11998 C CD  . ARG D 1 300 ? 138.725 134.032 160.571 1.00 80.53 ? 300 ARG D CD  1 
ATOM   11999 N NE  . ARG D 1 300 ? 138.011 134.532 161.741 1.00 80.53 ? 300 ARG D NE  1 
ATOM   12000 C CZ  . ARG D 1 300 ? 137.672 135.802 161.922 1.00 80.53 ? 300 ARG D CZ  1 
ATOM   12001 N NH1 . ARG D 1 300 ? 137.975 136.708 161.006 1.00 80.53 ? 300 ARG D NH1 1 
ATOM   12002 N NH2 . ARG D 1 300 ? 137.023 136.169 163.017 1.00 80.53 ? 300 ARG D NH2 1 
ATOM   12003 N N   . LEU D 1 301 ? 142.537 133.321 157.027 1.00 81.30 ? 301 LEU D N   1 
ATOM   12004 C CA  . LEU D 1 301 ? 143.076 132.539 155.919 1.00 81.30 ? 301 LEU D CA  1 
ATOM   12005 C C   . LEU D 1 301 ? 144.251 133.321 155.353 1.00 81.30 ? 301 LEU D C   1 
ATOM   12006 O O   . LEU D 1 301 ? 144.070 134.213 154.522 1.00 81.30 ? 301 LEU D O   1 
ATOM   12007 C CB  . LEU D 1 301 ? 142.008 132.301 154.860 1.00 81.30 ? 301 LEU D CB  1 
ATOM   12008 C CG  . LEU D 1 301 ? 142.189 131.081 153.958 1.00 81.30 ? 301 LEU D CG  1 
ATOM   12009 C CD1 . LEU D 1 301 ? 140.911 130.802 153.200 1.00 81.30 ? 301 LEU D CD1 1 
ATOM   12010 C CD2 . LEU D 1 301 ? 143.357 131.210 153.020 1.00 81.30 ? 301 LEU D CD2 1 
ATOM   12011 N N   . SER D 1 302 ? 145.460 132.983 155.789 1.00 84.28 ? 302 SER D N   1 
ATOM   12012 C CA  . SER D 1 302 ? 146.631 133.755 155.413 1.00 84.28 ? 302 SER D CA  1 
ATOM   12013 C C   . SER D 1 302 ? 147.782 132.817 155.089 1.00 84.28 ? 302 SER D C   1 
ATOM   12014 O O   . SER D 1 302 ? 147.925 131.752 155.693 1.00 84.28 ? 302 SER D O   1 
ATOM   12015 C CB  . SER D 1 302 ? 147.031 134.719 156.530 1.00 84.28 ? 302 SER D CB  1 
ATOM   12016 O OG  . SER D 1 302 ? 145.902 135.428 156.999 1.00 84.28 ? 302 SER D OG  1 
ATOM   12017 N N   . GLY D 1 303 ? 148.606 133.229 154.129 1.00 91.79 ? 303 GLY D N   1 
ATOM   12018 C CA  . GLY D 1 303 ? 149.753 132.454 153.723 1.00 91.79 ? 303 GLY D CA  1 
ATOM   12019 C C   . GLY D 1 303 ? 150.682 133.228 152.811 1.00 91.79 ? 303 GLY D C   1 
ATOM   12020 O O   . GLY D 1 303 ? 150.473 134.412 152.533 1.00 91.79 ? 303 GLY D O   1 
ATOM   12021 N N   . PRO D 1 304 ? 151.752 132.577 152.347 1.00 94.26 ? 304 PRO D N   1 
ATOM   12022 C CA  . PRO D 1 304 ? 152.618 133.232 151.353 1.00 94.26 ? 304 PRO D CA  1 
ATOM   12023 C C   . PRO D 1 304 ? 151.916 133.500 150.034 1.00 94.26 ? 304 PRO D C   1 
ATOM   12024 O O   . PRO D 1 304 ? 152.310 134.418 149.305 1.00 94.26 ? 304 PRO D O   1 
ATOM   12025 C CB  . PRO D 1 304 ? 153.779 132.240 151.188 1.00 94.26 ? 304 PRO D CB  1 
ATOM   12026 C CG  . PRO D 1 304 ? 153.752 131.399 152.406 1.00 94.26 ? 304 PRO D CG  1 
ATOM   12027 C CD  . PRO D 1 304 ? 152.323 131.312 152.835 1.00 94.26 ? 304 PRO D CD  1 
ATOM   12028 N N   . GLU D 1 305 ? 150.890 132.720 149.695 1.00 93.42 ? 305 GLU D N   1 
ATOM   12029 C CA  . GLU D 1 305 ? 150.203 132.910 148.424 1.00 93.42 ? 305 GLU D CA  1 
ATOM   12030 C C   . GLU D 1 305 ? 148.959 133.774 148.575 1.00 93.42 ? 305 GLU D C   1 
ATOM   12031 O O   . GLU D 1 305 ? 148.465 134.333 147.586 1.00 93.42 ? 305 GLU D O   1 
ATOM   12032 C CB  . GLU D 1 305 ? 149.844 131.556 147.817 1.00 93.42 ? 305 GLU D CB  1 
ATOM   12033 C CG  . GLU D 1 305 ? 151.039 130.801 147.273 1.00 93.42 ? 305 GLU D CG  1 
ATOM   12034 C CD  . GLU D 1 305 ? 151.720 129.956 148.326 1.00 93.42 ? 305 GLU D CD  1 
ATOM   12035 O OE1 . GLU D 1 305 ? 151.914 130.453 149.453 1.00 93.42 ? 305 GLU D OE1 1 
ATOM   12036 O OE2 . GLU D 1 305 ? 152.069 128.796 148.025 1.00 93.42 ? 305 GLU D OE2 1 
ATOM   12037 N N   . ILE D 1 306 ? 148.440 133.897 149.799 1.00 89.65 ? 306 ILE D N   1 
ATOM   12038 C CA  . ILE D 1 306 ? 147.269 134.733 150.033 1.00 89.65 ? 306 ILE D CA  1 
ATOM   12039 C C   . ILE D 1 306 ? 147.535 136.174 149.629 1.00 89.65 ? 306 ILE D C   1 
ATOM   12040 O O   . ILE D 1 306 ? 146.630 136.866 149.146 1.00 89.65 ? 306 ILE D O   1 
ATOM   12041 C CB  . ILE D 1 306 ? 146.830 134.636 151.503 1.00 89.65 ? 306 ILE D CB  1 
ATOM   12042 C CG1 . ILE D 1 306 ? 146.368 133.218 151.788 1.00 89.65 ? 306 ILE D CG1 1 
ATOM   12043 C CG2 . ILE D 1 306 ? 145.713 135.610 151.789 1.00 89.65 ? 306 ILE D CG2 1 
ATOM   12044 C CD1 . ILE D 1 306 ? 145.418 132.720 150.741 1.00 89.65 ? 306 ILE D CD1 1 
ATOM   12045 N N   . ASP D 1 307 ? 148.770 136.645 149.793 1.00 94.41 ? 307 ASP D N   1 
ATOM   12046 C CA  . ASP D 1 307 ? 149.095 138.009 149.395 1.00 94.41 ? 307 ASP D CA  1 
ATOM   12047 C C   . ASP D 1 307 ? 149.583 138.077 147.953 1.00 94.41 ? 307 ASP D C   1 
ATOM   12048 O O   . ASP D 1 307 ? 149.404 139.104 147.287 1.00 94.41 ? 307 ASP D O   1 
ATOM   12049 C CB  . ASP D 1 307 ? 150.140 138.598 150.341 1.00 94.41 ? 307 ASP D CB  1 
ATOM   12050 C CG  . ASP D 1 307 ? 151.404 137.777 150.387 1.00 94.41 ? 307 ASP D CG  1 
ATOM   12051 O OD1 . ASP D 1 307 ? 152.167 137.811 149.401 1.00 94.41 ? 307 ASP D OD1 1 
ATOM   12052 O OD2 . ASP D 1 307 ? 151.634 137.093 151.404 1.00 94.41 ? 307 ASP D OD2 1 
ATOM   12053 N N   . TYR D 1 308 ? 150.215 137.006 147.460 1.00 91.96 ? 308 TYR D N   1 
ATOM   12054 C CA  . TYR D 1 308 ? 150.580 136.943 146.048 1.00 91.96 ? 308 TYR D CA  1 
ATOM   12055 C C   . TYR D 1 308 ? 149.384 137.247 145.165 1.00 91.96 ? 308 TYR D C   1 
ATOM   12056 O O   . TYR D 1 308 ? 149.435 138.142 144.314 1.00 91.96 ? 308 TYR D O   1 
ATOM   12057 C CB  . TYR D 1 308 ? 151.135 135.565 145.692 1.00 91.96 ? 308 TYR D CB  1 
ATOM   12058 C CG  . TYR D 1 308 ? 152.548 135.322 146.133 1.00 91.96 ? 308 TYR D CG  1 
ATOM   12059 C CD1 . TYR D 1 308 ? 153.228 136.255 146.891 1.00 91.96 ? 308 TYR D CD1 1 
ATOM   12060 C CD2 . TYR D 1 308 ? 153.205 134.155 145.784 1.00 91.96 ? 308 TYR D CD2 1 
ATOM   12061 C CE1 . TYR D 1 308 ? 154.520 136.027 147.299 1.00 91.96 ? 308 TYR D CE1 1 
ATOM   12062 C CE2 . TYR D 1 308 ? 154.496 133.918 146.185 1.00 91.96 ? 308 TYR D CE2 1 
ATOM   12063 C CZ  . TYR D 1 308 ? 155.149 134.857 146.942 1.00 91.96 ? 308 TYR D CZ  1 
ATOM   12064 O OH  . TYR D 1 308 ? 156.442 134.626 147.345 1.00 91.96 ? 308 TYR D OH  1 
ATOM   12065 N N   . GLY D 1 309 ? 148.293 136.506 145.357 1.00 86.76 ? 309 GLY D N   1 
ATOM   12066 C CA  . GLY D 1 309 ? 147.108 136.739 144.551 1.00 86.76 ? 309 GLY D CA  1 
ATOM   12067 C C   . GLY D 1 309 ? 146.491 138.100 144.793 1.00 86.76 ? 309 GLY D C   1 
ATOM   12068 O O   . GLY D 1 309 ? 145.943 138.720 143.872 1.00 86.76 ? 309 GLY D O   1 
ATOM   12069 N N   . PHE D 1 310 ? 146.574 138.593 146.029 1.00 86.03 ? 310 PHE D N   1 
ATOM   12070 C CA  . PHE D 1 310 ? 145.922 139.857 146.340 1.00 86.03 ? 310 PHE D CA  1 
ATOM   12071 C C   . PHE D 1 310 ? 146.622 141.024 145.662 1.00 86.03 ? 310 PHE D C   1 
ATOM   12072 O O   . PHE D 1 310 ? 145.966 141.975 145.222 1.00 86.03 ? 310 PHE D O   1 
ATOM   12073 C CB  . PHE D 1 310 ? 145.869 140.084 147.843 1.00 86.03 ? 310 PHE D CB  1 
ATOM   12074 C CG  . PHE D 1 310 ? 145.312 141.417 148.209 1.00 86.03 ? 310 PHE D CG  1 
ATOM   12075 C CD1 . PHE D 1 310 ? 143.984 141.711 147.957 1.00 86.03 ? 310 PHE D CD1 1 
ATOM   12076 C CD2 . PHE D 1 310 ? 146.114 142.389 148.774 1.00 86.03 ? 310 PHE D CD2 1 
ATOM   12077 C CE1 . PHE D 1 310 ? 143.462 142.941 148.279 1.00 86.03 ? 310 PHE D CE1 1 
ATOM   12078 C CE2 . PHE D 1 310 ? 145.595 143.626 149.098 1.00 86.03 ? 310 PHE D CE2 1 
ATOM   12079 C CZ  . PHE D 1 310 ? 144.267 143.901 148.851 1.00 86.03 ? 310 PHE D CZ  1 
ATOM   12080 N N   . LYS D 1 311 ? 147.951 140.985 145.590 1.00 86.57 ? 311 LYS D N   1 
ATOM   12081 C CA  . LYS D 1 311 ? 148.668 142.031 144.873 1.00 86.57 ? 311 LYS D CA  1 
ATOM   12082 C C   . LYS D 1 311 ? 148.157 142.143 143.449 1.00 86.57 ? 311 LYS D C   1 
ATOM   12083 O O   . LYS D 1 311 ? 147.886 143.243 142.953 1.00 86.57 ? 311 LYS D O   1 
ATOM   12084 C CB  . LYS D 1 311 ? 150.164 141.746 144.868 1.00 86.57 ? 311 LYS D CB  1 
ATOM   12085 C CG  . LYS D 1 311 ? 150.997 142.848 144.225 1.00 86.57 ? 311 LYS D CG  1 
ATOM   12086 C CD  . LYS D 1 311 ? 151.187 142.648 142.726 1.00 86.57 ? 311 LYS D CD  1 
ATOM   12087 C CE  . LYS D 1 311 ? 151.859 141.329 142.414 1.00 86.57 ? 311 LYS D CE  1 
ATOM   12088 N NZ  . LYS D 1 311 ? 152.134 141.214 140.956 1.00 86.57 ? 311 LYS D NZ  1 
ATOM   12089 N N   . ILE D 1 312 ? 148.019 141.004 142.775 1.00 84.96 ? 312 ILE D N   1 
ATOM   12090 C CA  . ILE D 1 312 ? 147.630 141.021 141.372 1.00 84.96 ? 312 ILE D CA  1 
ATOM   12091 C C   . ILE D 1 312 ? 146.192 141.492 141.225 1.00 84.96 ? 312 ILE D C   1 
ATOM   12092 O O   . ILE D 1 312 ? 145.855 142.216 140.275 1.00 84.96 ? 312 ILE D O   1 
ATOM   12093 C CB  . ILE D 1 312 ? 147.840 139.634 140.744 1.00 84.96 ? 312 ILE D CB  1 
ATOM   12094 C CG1 . ILE D 1 312 ? 149.309 139.238 140.828 1.00 84.96 ? 312 ILE D CG1 1 
ATOM   12095 C CG2 . ILE D 1 312 ? 147.412 139.647 139.302 1.00 84.96 ? 312 ILE D CG2 1 
ATOM   12096 C CD1 . ILE D 1 312 ? 149.579 137.809 140.443 1.00 84.96 ? 312 ILE D CD1 1 
ATOM   12097 N N   . VAL D 1 313 ? 145.319 141.100 142.155 1.00 83.10 ? 313 VAL D N   1 
ATOM   12098 C CA  . VAL D 1 313 ? 143.941 141.542 141.986 1.00 83.10 ? 313 VAL D CA  1 
ATOM   12099 C C   . VAL D 1 313 ? 143.816 143.030 142.260 1.00 83.10 ? 313 VAL D C   1 
ATOM   12100 O O   . VAL D 1 313 ? 143.040 143.713 141.594 1.00 83.10 ? 313 VAL D O   1 
ATOM   12101 C CB  . VAL D 1 313 ? 142.948 140.735 142.837 1.00 83.10 ? 313 VAL D CB  1 
ATOM   12102 C CG1 . VAL D 1 313 ? 143.117 141.027 144.307 1.00 83.10 ? 313 VAL D CG1 1 
ATOM   12103 C CG2 . VAL D 1 313 ? 141.528 141.042 142.375 1.00 83.10 ? 313 VAL D CG2 1 
ATOM   12104 N N   . SER D 1 314 ? 144.585 143.577 143.199 1.00 85.13 ? 314 SER D N   1 
ATOM   12105 C CA  . SER D 1 314 ? 144.551 145.025 143.376 1.00 85.13 ? 314 SER D CA  1 
ATOM   12106 C C   . SER D 1 314 ? 145.112 145.726 142.149 1.00 85.13 ? 314 SER D C   1 
ATOM   12107 O O   . SER D 1 314 ? 144.610 146.780 141.734 1.00 85.13 ? 314 SER D O   1 
ATOM   12108 C CB  . SER D 1 314 ? 145.330 145.420 144.625 1.00 85.13 ? 314 SER D CB  1 
ATOM   12109 O OG  . SER D 1 314 ? 146.702 145.607 144.330 1.00 85.13 ? 314 SER D OG  1 
ATOM   12110 N N   . GLN D 1 315 ? 146.148 145.137 141.551 1.00 84.08 ? 315 GLN D N   1 
ATOM   12111 C CA  . GLN D 1 315 ? 146.721 145.664 140.322 1.00 84.08 ? 315 GLN D CA  1 
ATOM   12112 C C   . GLN D 1 315 ? 145.657 145.809 139.243 1.00 84.08 ? 315 GLN D C   1 
ATOM   12113 O O   . GLN D 1 315 ? 145.368 146.919 138.777 1.00 84.08 ? 315 GLN D O   1 
ATOM   12114 C CB  . GLN D 1 315 ? 147.848 144.737 139.867 1.00 84.08 ? 315 GLN D CB  1 
ATOM   12115 C CG  . GLN D 1 315 ? 148.454 145.048 138.521 1.00 84.08 ? 315 GLN D CG  1 
ATOM   12116 C CD  . GLN D 1 315 ? 149.616 144.126 138.210 1.00 84.08 ? 315 GLN D CD  1 
ATOM   12117 O OE1 . GLN D 1 315 ? 150.020 143.320 139.048 1.00 84.08 ? 315 GLN D OE1 1 
ATOM   12118 N NE2 . GLN D 1 315 ? 150.159 144.237 137.004 1.00 84.08 ? 315 GLN D NE2 1 
ATOM   12119 N N   . MET D 1 316 ? 145.041 144.697 138.849 1.00 82.65 ? 316 MET D N   1 
ATOM   12120 C CA  . MET D 1 316 ? 144.050 144.791 137.783 1.00 82.65 ? 316 MET D CA  1 
ATOM   12121 C C   . MET D 1 316 ? 142.813 145.554 138.233 1.00 82.65 ? 316 MET D C   1 
ATOM   12122 O O   . MET D 1 316 ? 142.112 146.139 137.404 1.00 82.65 ? 316 MET D O   1 
ATOM   12123 C CB  . MET D 1 316 ? 143.651 143.414 137.276 1.00 82.65 ? 316 MET D CB  1 
ATOM   12124 C CG  . MET D 1 316 ? 143.111 143.468 135.861 1.00 82.65 ? 316 MET D CG  1 
ATOM   12125 S SD  . MET D 1 316 ? 141.941 142.168 135.476 1.00 82.65 ? 316 MET D SD  1 
ATOM   12126 C CE  . MET D 1 316 ? 140.699 142.449 136.731 1.00 82.65 ? 316 MET D CE  1 
ATOM   12127 N N   . TRP D 1 317 ? 142.543 145.578 139.535 1.00 83.97 ? 317 TRP D N   1 
ATOM   12128 C CA  . TRP D 1 317 ? 141.440 146.356 140.075 1.00 83.97 ? 317 TRP D CA  1 
ATOM   12129 C C   . TRP D 1 317 ? 141.594 147.822 139.719 1.00 83.97 ? 317 TRP D C   1 
ATOM   12130 O O   . TRP D 1 317 ? 140.748 148.402 139.029 1.00 83.97 ? 317 TRP D O   1 
ATOM   12131 C CB  . TRP D 1 317 ? 141.395 146.152 141.592 1.00 83.97 ? 317 TRP D CB  1 
ATOM   12132 C CG  . TRP D 1 317 ? 140.638 147.165 142.396 1.00 83.97 ? 317 TRP D CG  1 
ATOM   12133 C CD1 . TRP D 1 317 ? 140.994 148.459 142.638 1.00 83.97 ? 317 TRP D CD1 1 
ATOM   12134 C CD2 . TRP D 1 317 ? 139.441 146.939 143.136 1.00 83.97 ? 317 TRP D CD2 1 
ATOM   12135 N NE1 . TRP D 1 317 ? 140.071 149.062 143.444 1.00 83.97 ? 317 TRP D NE1 1 
ATOM   12136 C CE2 . TRP D 1 317 ? 139.108 148.147 143.769 1.00 83.97 ? 317 TRP D CE2 1 
ATOM   12137 C CE3 . TRP D 1 317 ? 138.607 145.837 143.311 1.00 83.97 ? 317 TRP D CE3 1 
ATOM   12138 C CZ2 . TRP D 1 317 ? 137.985 148.282 144.565 1.00 83.97 ? 317 TRP D CZ2 1 
ATOM   12139 C CZ3 . TRP D 1 317 ? 137.488 145.976 144.100 1.00 83.97 ? 317 TRP D CZ3 1 
ATOM   12140 C CH2 . TRP D 1 317 ? 137.188 147.188 144.718 1.00 83.97 ? 317 TRP D CH2 1 
ATOM   12141 N N   . ASP D 1 318 ? 142.669 148.446 140.195 1.00 86.61 ? 318 ASP D N   1 
ATOM   12142 C CA  . ASP D 1 318 ? 142.826 149.860 139.895 1.00 86.61 ? 318 ASP D CA  1 
ATOM   12143 C C   . ASP D 1 318 ? 143.074 150.086 138.414 1.00 86.61 ? 318 ASP D C   1 
ATOM   12144 O O   . ASP D 1 318 ? 142.732 151.154 137.898 1.00 86.61 ? 318 ASP D O   1 
ATOM   12145 C CB  . ASP D 1 318 ? 143.923 150.485 140.764 1.00 86.61 ? 318 ASP D CB  1 
ATOM   12146 C CG  . ASP D 1 318 ? 145.327 150.059 140.376 1.00 86.61 ? 318 ASP D CG  1 
ATOM   12147 O OD1 . ASP D 1 318 ? 145.538 149.455 139.306 1.00 86.61 ? 318 ASP D OD1 1 
ATOM   12148 O OD2 . ASP D 1 318 ? 146.248 150.360 141.162 1.00 86.61 ? 318 ASP D OD2 1 
ATOM   12149 N N   . ALA D 1 319 ? 143.621 149.088 137.715 1.00 84.01 ? 319 ALA D N   1 
ATOM   12150 C CA  . ALA D 1 319 ? 143.742 149.184 136.266 1.00 84.01 ? 319 ALA D CA  1 
ATOM   12151 C C   . ALA D 1 319 ? 142.383 149.408 135.612 1.00 84.01 ? 319 ALA D C   1 
ATOM   12152 O O   . ALA D 1 319 ? 142.137 150.455 135.005 1.00 84.01 ? 319 ALA D O   1 
ATOM   12153 C CB  . ALA D 1 319 ? 144.407 147.922 135.718 1.00 84.01 ? 319 ALA D CB  1 
ATOM   12154 N N   . ILE D 1 320 ? 141.475 148.438 135.743 1.00 80.92 ? 320 ILE D N   1 
ATOM   12155 C CA  . ILE D 1 320 ? 140.204 148.521 135.026 1.00 80.92 ? 320 ILE D CA  1 
ATOM   12156 C C   . ILE D 1 320 ? 139.210 149.459 135.680 1.00 80.92 ? 320 ILE D C   1 
ATOM   12157 O O   . ILE D 1 320 ? 138.183 149.774 135.070 1.00 80.92 ? 320 ILE D O   1 
ATOM   12158 C CB  . ILE D 1 320 ? 139.517 147.153 134.878 1.00 80.92 ? 320 ILE D CB  1 
ATOM   12159 C CG1 . ILE D 1 320 ? 138.625 147.146 133.637 1.00 80.92 ? 320 ILE D CG1 1 
ATOM   12160 C CG2 . ILE D 1 320 ? 138.675 146.852 136.099 1.00 80.92 ? 320 ILE D CG2 1 
ATOM   12161 C CD1 . ILE D 1 320 ? 138.180 145.772 133.201 1.00 80.92 ? 320 ILE D CD1 1 
ATOM   12162 N N   . TYR D 1 321 ? 139.468 149.918 136.900 1.00 83.03 ? 321 TYR D N   1 
ATOM   12163 C CA  . TYR D 1 321 ? 138.585 150.889 137.523 1.00 83.03 ? 321 TYR D CA  1 
ATOM   12164 C C   . TYR D 1 321 ? 139.090 152.314 137.391 1.00 83.03 ? 321 TYR D C   1 
ATOM   12165 O O   . TYR D 1 321 ? 138.340 153.250 137.683 1.00 83.03 ? 321 TYR D O   1 
ATOM   12166 C CB  . TYR D 1 321 ? 138.383 150.542 138.997 1.00 83.03 ? 321 TYR D CB  1 
ATOM   12167 C CG  . TYR D 1 321 ? 137.509 149.339 139.180 1.00 83.03 ? 321 TYR D CG  1 
ATOM   12168 C CD1 . TYR D 1 321 ? 136.366 149.186 138.427 1.00 83.03 ? 321 TYR D CD1 1 
ATOM   12169 C CD2 . TYR D 1 321 ? 137.825 148.355 140.099 1.00 83.03 ? 321 TYR D CD2 1 
ATOM   12170 C CE1 . TYR D 1 321 ? 135.558 148.095 138.580 1.00 83.03 ? 321 TYR D CE1 1 
ATOM   12171 C CE2 . TYR D 1 321 ? 137.022 147.254 140.263 1.00 83.03 ? 321 TYR D CE2 1 
ATOM   12172 C CZ  . TYR D 1 321 ? 135.886 147.131 139.498 1.00 83.03 ? 321 TYR D CZ  1 
ATOM   12173 O OH  . TYR D 1 321 ? 135.064 146.041 139.639 1.00 83.03 ? 321 TYR D OH  1 
ATOM   12174 N N   . SER D 1 322 ? 140.336 152.496 136.954 1.00 85.71 ? 322 SER D N   1 
ATOM   12175 C CA  . SER D 1 322 ? 140.821 153.834 136.655 1.00 85.71 ? 322 SER D CA  1 
ATOM   12176 C C   . SER D 1 322 ? 140.027 154.466 135.519 1.00 85.71 ? 322 SER D C   1 
ATOM   12177 O O   . SER D 1 322 ? 139.862 155.689 135.475 1.00 85.71 ? 322 SER D O   1 
ATOM   12178 C CB  . SER D 1 322 ? 142.301 153.767 136.305 1.00 85.71 ? 322 SER D CB  1 
ATOM   12179 O OG  . SER D 1 322 ? 142.497 152.892 135.207 1.00 85.71 ? 322 SER D OG  1 
ATOM   12180 N N   . LYS D 1 323 ? 139.530 153.657 134.591 1.00 85.26 ? 323 LYS D N   1 
ATOM   12181 C CA  . LYS D 1 323 ? 138.751 154.190 133.486 1.00 85.26 ? 323 LYS D CA  1 
ATOM   12182 C C   . LYS D 1 323 ? 137.361 154.597 133.954 1.00 85.26 ? 323 LYS D C   1 
ATOM   12183 O O   . LYS D 1 323 ? 136.926 154.285 135.064 1.00 85.26 ? 323 LYS D O   1 
ATOM   12184 C CB  . LYS D 1 323 ? 138.629 153.166 132.360 1.00 85.26 ? 323 LYS D CB  1 
ATOM   12185 C CG  . LYS D 1 323 ? 139.876 152.353 132.141 1.00 85.26 ? 323 LYS D CG  1 
ATOM   12186 C CD  . LYS D 1 323 ? 141.061 153.233 131.813 1.00 85.26 ? 323 LYS D CD  1 
ATOM   12187 C CE  . LYS D 1 323 ? 142.353 152.444 131.889 1.00 85.26 ? 323 LYS D CE  1 
ATOM   12188 N NZ  . LYS D 1 323 ? 142.494 151.759 133.197 1.00 85.26 ? 323 LYS D NZ  1 
ATOM   12189 N N   . GLU D 1 324 ? 136.665 155.313 133.082 1.00 88.92 ? 324 GLU D N   1 
ATOM   12190 C CA  . GLU D 1 324 ? 135.313 155.759 133.358 1.00 88.92 ? 324 GLU D CA  1 
ATOM   12191 C C   . GLU D 1 324 ? 134.299 154.788 132.770 1.00 88.92 ? 324 GLU D C   1 
ATOM   12192 O O   . GLU D 1 324 ? 134.618 153.932 131.943 1.00 88.92 ? 324 GLU D O   1 
ATOM   12193 C CB  . GLU D 1 324 ? 135.077 157.152 132.783 1.00 88.92 ? 324 GLU D CB  1 
ATOM   12194 C CG  . GLU D 1 324 ? 134.884 157.158 131.282 1.00 88.92 ? 324 GLU D CG  1 
ATOM   12195 C CD  . GLU D 1 324 ? 136.179 156.918 130.541 1.00 88.92 ? 324 GLU D CD  1 
ATOM   12196 O OE1 . GLU D 1 324 ? 137.250 157.076 131.160 1.00 88.92 ? 324 GLU D OE1 1 
ATOM   12197 O OE2 . GLU D 1 324 ? 136.132 156.565 129.344 1.00 88.92 ? 324 GLU D OE2 1 
ATOM   12198 N N   . LEU D 1 325 ? 133.077 154.934 133.204 1.00 87.45 ? 325 LEU D N   1 
ATOM   12199 C CA  . LEU D 1 325 ? 132.010 154.144 132.630 1.00 87.45 ? 325 LEU D CA  1 
ATOM   12200 C C   . LEU D 1 325 ? 131.571 154.762 131.306 1.00 87.45 ? 325 LEU D C   1 
ATOM   12201 O O   . LEU D 1 325 ? 131.698 155.971 131.107 1.00 87.45 ? 325 LEU D O   1 
ATOM   12202 C CB  . LEU D 1 325 ? 130.835 154.076 133.595 1.00 87.45 ? 325 LEU D CB  1 
ATOM   12203 C CG  . LEU D 1 325 ? 129.779 152.993 133.402 1.00 87.45 ? 325 LEU D CG  1 
ATOM   12204 C CD1 . LEU D 1 325 ? 129.309 152.480 134.746 1.00 87.45 ? 325 LEU D CD1 1 
ATOM   12205 C CD2 . LEU D 1 325 ? 128.613 153.534 132.604 1.00 87.45 ? 325 LEU D CD2 1 
ATOM   12206 N N   . PRO D 1 326 ? 131.089 153.950 130.369 1.00 87.64 ? 326 PRO D N   1 
ATOM   12207 C CA  . PRO D 1 326 ? 130.545 154.511 129.128 1.00 87.64 ? 326 PRO D CA  1 
ATOM   12208 C C   . PRO D 1 326 ? 129.387 155.457 129.380 1.00 87.64 ? 326 PRO D C   1 
ATOM   12209 O O   . PRO D 1 326 ? 128.325 155.038 129.847 1.00 87.64 ? 326 PRO D O   1 
ATOM   12210 C CB  . PRO D 1 326 ? 130.091 153.271 128.351 1.00 87.64 ? 326 PRO D CB  1 
ATOM   12211 C CG  . PRO D 1 326 ? 130.962 152.191 128.844 1.00 87.64 ? 326 PRO D CG  1 
ATOM   12212 C CD  . PRO D 1 326 ? 131.258 152.490 130.284 1.00 87.64 ? 326 PRO D CD  1 
ATOM   12213 N N   . GLY D 1 327 ? 129.580 156.730 129.063 1.00 93.18 ? 327 GLY D N   1 
ATOM   12214 C CA  . GLY D 1 327 ? 128.549 157.723 129.249 1.00 93.18 ? 327 GLY D CA  1 
ATOM   12215 C C   . GLY D 1 327 ? 128.664 158.547 130.509 1.00 93.18 ? 327 GLY D C   1 
ATOM   12216 O O   . GLY D 1 327 ? 127.681 159.186 130.899 1.00 93.18 ? 327 GLY D O   1 
ATOM   12217 N N   . GLY D 1 328 ? 129.817 158.537 131.169 1.00 97.04 ? 328 GLY D N   1 
ATOM   12218 C CA  . GLY D 1 328 ? 130.041 159.385 132.316 1.00 97.04 ? 328 GLY D CA  1 
ATOM   12219 C C   . GLY D 1 328 ? 129.283 159.019 133.571 1.00 97.04 ? 328 GLY D C   1 
ATOM   12220 O O   . GLY D 1 328 ? 129.352 159.772 134.549 1.00 97.04 ? 328 GLY D O   1 
ATOM   12221 N N   . LYS D 1 329 ? 128.557 157.904 133.588 1.00 96.31 ? 329 LYS D N   1 
ATOM   12222 C CA  . LYS D 1 329 ? 127.900 157.482 134.817 1.00 96.31 ? 329 LYS D CA  1 
ATOM   12223 C C   . LYS D 1 329 ? 128.947 157.151 135.871 1.00 96.31 ? 329 LYS D C   1 
ATOM   12224 O O   . LYS D 1 329 ? 130.014 156.616 135.564 1.00 96.31 ? 329 LYS D O   1 
ATOM   12225 C CB  . LYS D 1 329 ? 126.999 156.278 134.562 1.00 96.31 ? 329 LYS D CB  1 
ATOM   12226 C CG  . LYS D 1 329 ? 125.730 156.615 133.800 1.00 96.31 ? 329 LYS D CG  1 
ATOM   12227 C CD  . LYS D 1 329 ? 124.705 155.501 133.915 1.00 96.31 ? 329 LYS D CD  1 
ATOM   12228 C CE  . LYS D 1 329 ? 124.421 155.159 135.369 1.00 96.31 ? 329 LYS D CE  1 
ATOM   12229 N NZ  . LYS D 1 329 ? 123.979 156.351 136.143 1.00 96.31 ? 329 LYS D NZ  1 
ATOM   12230 N N   . GLN D 1 330 ? 128.643 157.485 137.119 1.00 95.78 ? 330 GLN D N   1 
ATOM   12231 C CA  . GLN D 1 330 ? 129.640 157.399 138.173 1.00 95.78 ? 330 GLN D CA  1 
ATOM   12232 C C   . GLN D 1 330 ? 129.672 156.011 138.798 1.00 95.78 ? 330 GLN D C   1 
ATOM   12233 O O   . GLN D 1 330 ? 128.643 155.346 138.942 1.00 95.78 ? 330 GLN D O   1 
ATOM   12234 C CB  . GLN D 1 330 ? 129.366 158.449 139.247 1.00 95.78 ? 330 GLN D CB  1 
ATOM   12235 C CG  . GLN D 1 330 ? 129.662 159.854 138.787 1.00 95.78 ? 330 GLN D CG  1 
ATOM   12236 C CD  . GLN D 1 330 ? 130.957 159.933 138.010 1.00 95.78 ? 330 GLN D CD  1 
ATOM   12237 O OE1 . GLN D 1 330 ? 130.960 160.235 136.818 1.00 95.78 ? 330 GLN D OE1 1 
ATOM   12238 N NE2 . GLN D 1 330 ? 132.068 159.654 138.681 1.00 95.78 ? 330 GLN D NE2 1 
ATOM   12239 N N   . ARG D 1 331 ? 130.875 155.577 139.169 1.00 93.13 ? 331 ARG D N   1 
ATOM   12240 C CA  . ARG D 1 331 ? 131.066 154.309 139.865 1.00 93.13 ? 331 ARG D CA  1 
ATOM   12241 C C   . ARG D 1 331 ? 131.133 154.591 141.364 1.00 93.13 ? 331 ARG D C   1 
ATOM   12242 O O   . ARG D 1 331 ? 131.991 155.346 141.831 1.00 93.13 ? 331 ARG D O   1 
ATOM   12243 C CB  . ARG D 1 331 ? 132.311 153.581 139.352 1.00 93.13 ? 331 ARG D CB  1 
ATOM   12244 C CG  . ARG D 1 331 ? 133.645 154.241 139.657 1.00 93.13 ? 331 ARG D CG  1 
ATOM   12245 C CD  . ARG D 1 331 ? 134.819 153.448 139.100 1.00 93.13 ? 331 ARG D CD  1 
ATOM   12246 N NE  . ARG D 1 331 ? 134.862 153.481 137.643 1.00 93.13 ? 331 ARG D NE  1 
ATOM   12247 C CZ  . ARG D 1 331 ? 134.593 152.442 136.863 1.00 93.13 ? 331 ARG D CZ  1 
ATOM   12248 N NH1 . ARG D 1 331 ? 134.262 151.278 137.396 1.00 93.13 ? 331 ARG D NH1 1 
ATOM   12249 N NH2 . ARG D 1 331 ? 134.653 152.571 135.547 1.00 93.13 ? 331 ARG D NH2 1 
ATOM   12250 N N   . GLU D 1 332 ? 130.188 154.025 142.111 1.00 93.19 ? 332 GLU D N   1 
ATOM   12251 C CA  . GLU D 1 332 ? 130.153 154.229 143.554 1.00 93.19 ? 332 GLU D CA  1 
ATOM   12252 C C   . GLU D 1 332 ? 130.920 153.131 144.281 1.00 93.19 ? 332 GLU D C   1 
ATOM   12253 O O   . GLU D 1 332 ? 131.747 153.407 145.155 1.00 93.19 ? 332 GLU D O   1 
ATOM   12254 C CB  . GLU D 1 332 ? 128.700 154.297 144.034 1.00 93.19 ? 332 GLU D CB  1 
ATOM   12255 C CG  . GLU D 1 332 ? 127.814 153.146 143.575 1.00 93.19 ? 332 GLU D CG  1 
ATOM   12256 C CD  . GLU D 1 332 ? 127.275 153.336 142.172 1.00 93.19 ? 332 GLU D CD  1 
ATOM   12257 O OE1 . GLU D 1 332 ? 127.881 154.100 141.395 1.00 93.19 ? 332 GLU D OE1 1 
ATOM   12258 O OE2 . GLU D 1 332 ? 126.240 152.721 141.846 1.00 93.19 ? 332 GLU D OE2 1 
ATOM   12259 N N   . ASN D 1 333 ? 130.660 151.880 143.926 1.00 87.67 ? 333 ASN D N   1 
ATOM   12260 C CA  . ASN D 1 333 ? 131.317 150.735 144.527 1.00 87.67 ? 333 ASN D CA  1 
ATOM   12261 C C   . ASN D 1 333 ? 131.702 149.757 143.427 1.00 87.67 ? 333 ASN D C   1 
ATOM   12262 O O   . ASN D 1 333 ? 131.491 150.004 142.238 1.00 87.67 ? 333 ASN D O   1 
ATOM   12263 C CB  . ASN D 1 333 ? 130.422 150.063 145.577 1.00 87.67 ? 333 ASN D CB  1 
ATOM   12264 C CG  . ASN D 1 333 ? 129.036 149.763 145.055 1.00 87.67 ? 333 ASN D CG  1 
ATOM   12265 O OD1 . ASN D 1 333 ? 128.772 149.864 143.860 1.00 87.67 ? 333 ASN D OD1 1 
ATOM   12266 N ND2 . ASN D 1 333 ? 128.134 149.404 145.956 1.00 87.67 ? 333 ASN D ND2 1 
ATOM   12267 N N   . ASN D 1 334 ? 132.276 148.635 143.832 1.00 80.88 ? 334 ASN D N   1 
ATOM   12268 C CA  . ASN D 1 334 ? 132.818 147.662 142.903 1.00 80.88 ? 334 ASN D CA  1 
ATOM   12269 C C   . ASN D 1 334 ? 132.244 146.292 143.209 1.00 80.88 ? 334 ASN D C   1 
ATOM   12270 O O   . ASN D 1 334 ? 132.268 145.849 144.362 1.00 80.88 ? 334 ASN D O   1 
ATOM   12271 C CB  . ASN D 1 334 ? 134.335 147.655 142.995 1.00 80.88 ? 334 ASN D CB  1 
ATOM   12272 C CG  . ASN D 1 334 ? 134.930 148.944 142.513 1.00 80.88 ? 334 ASN D CG  1 
ATOM   12273 O OD1 . ASN D 1 334 ? 134.754 149.324 141.361 1.00 80.88 ? 334 ASN D OD1 1 
ATOM   12274 N ND2 . ASN D 1 334 ? 135.580 149.665 143.408 1.00 80.88 ? 334 ASN D ND2 1 
ATOM   12275 N N   . HIS D 1 335 ? 131.732 145.629 142.178 1.00 74.90 ? 335 HIS D N   1 
ATOM   12276 C CA  . HIS D 1 335 ? 131.080 144.333 142.322 1.00 74.90 ? 335 HIS D CA  1 
ATOM   12277 C C   . HIS D 1 335 ? 132.120 143.235 142.135 1.00 74.90 ? 335 HIS D C   1 
ATOM   12278 O O   . HIS D 1 335 ? 132.665 143.052 141.035 1.00 74.90 ? 335 HIS D O   1 
ATOM   12279 C CB  . HIS D 1 335 ? 129.936 144.203 141.324 1.00 74.90 ? 335 HIS D CB  1 
ATOM   12280 C CG  . HIS D 1 335 ? 128.945 143.141 141.671 1.00 74.90 ? 335 HIS D CG  1 
ATOM   12281 N ND1 . HIS D 1 335 ? 128.290 143.103 142.880 1.00 74.90 ? 335 HIS D ND1 1 
ATOM   12282 C CD2 . HIS D 1 335 ? 128.465 142.101 140.952 1.00 74.90 ? 335 HIS D CD2 1 
ATOM   12283 C CE1 . HIS D 1 335 ? 127.469 142.069 142.901 1.00 74.90 ? 335 HIS D CE1 1 
ATOM   12284 N NE2 . HIS D 1 335 ? 127.554 141.447 141.742 1.00 74.90 ? 335 HIS D NE2 1 
ATOM   12285 N N   . ILE D 1 336 ? 132.412 142.521 143.219 1.00 71.59 ? 336 ILE D N   1 
ATOM   12286 C CA  . ILE D 1 336 ? 133.381 141.442 143.214 1.00 71.59 ? 336 ILE D CA  1 
ATOM   12287 C C   . ILE D 1 336 ? 132.684 140.176 143.680 1.00 71.59 ? 336 ILE D C   1 
ATOM   12288 O O   . ILE D 1 336 ? 131.668 140.213 144.380 1.00 71.59 ? 336 ILE D O   1 
ATOM   12289 C CB  . ILE D 1 336 ? 134.590 141.757 144.107 1.00 71.59 ? 336 ILE D CB  1 
ATOM   12290 C CG1 . ILE D 1 336 ? 134.263 141.460 145.562 1.00 71.59 ? 336 ILE D CG1 1 
ATOM   12291 C CG2 . ILE D 1 336 ? 134.968 143.206 143.979 1.00 71.59 ? 336 ILE D CG2 1 
ATOM   12292 C CD1 . ILE D 1 336 ? 135.383 141.790 146.493 1.00 71.59 ? 336 ILE D CD1 1 
ATOM   12293 N N   . GLN D 1 337 ? 133.237 139.048 143.268 1.00 69.61 ? 337 GLN D N   1 
ATOM   12294 C CA  . GLN D 1 337 ? 132.757 137.750 143.709 1.00 69.61 ? 337 GLN D CA  1 
ATOM   12295 C C   . GLN D 1 337 ? 133.925 136.998 144.313 1.00 69.61 ? 337 GLN D C   1 
ATOM   12296 O O   . GLN D 1 337 ? 135.080 137.335 144.075 1.00 69.61 ? 337 GLN D O   1 
ATOM   12297 C CB  . GLN D 1 337 ? 132.146 136.950 142.567 1.00 69.61 ? 337 GLN D CB  1 
ATOM   12298 C CG  . GLN D 1 337 ? 131.006 137.650 141.881 1.00 69.61 ? 337 GLN D CG  1 
ATOM   12299 C CD  . GLN D 1 337 ? 130.629 136.976 140.587 1.00 69.61 ? 337 GLN D CD  1 
ATOM   12300 O OE1 . GLN D 1 337 ? 131.460 136.333 139.952 1.00 69.61 ? 337 GLN D OE1 1 
ATOM   12301 N NE2 . GLN D 1 337 ? 129.369 137.105 140.193 1.00 69.61 ? 337 GLN D NE2 1 
ATOM   12302 N N   . ILE D 1 338 ? 133.632 135.971 145.097 1.00 68.83 ? 338 ILE D N   1 
ATOM   12303 C CA  . ILE D 1 338 ? 134.678 135.277 145.825 1.00 68.83 ? 338 ILE D CA  1 
ATOM   12304 C C   . ILE D 1 338 ? 134.285 133.822 146.009 1.00 68.83 ? 338 ILE D C   1 
ATOM   12305 O O   . ILE D 1 338 ? 133.104 133.487 146.139 1.00 68.83 ? 338 ILE D O   1 
ATOM   12306 C CB  . ILE D 1 338 ? 134.957 135.963 147.173 1.00 68.83 ? 338 ILE D CB  1 
ATOM   12307 C CG1 . ILE D 1 338 ? 136.218 135.401 147.811 1.00 68.83 ? 338 ILE D CG1 1 
ATOM   12308 C CG2 . ILE D 1 338 ? 133.774 135.824 148.075 1.00 68.83 ? 338 ILE D CG2 1 
ATOM   12309 C CD1 . ILE D 1 338 ? 137.439 135.602 146.987 1.00 68.83 ? 338 ILE D CD1 1 
ATOM   12310 N N   . ASN D 1 339 ? 135.297 132.959 146.012 1.00 69.04 ? 339 ASN D N   1 
ATOM   12311 C CA  . ASN D 1 339 ? 135.115 131.518 146.025 1.00 69.04 ? 339 ASN D CA  1 
ATOM   12312 C C   . ASN D 1 339 ? 136.280 130.892 146.769 1.00 69.04 ? 339 ASN D C   1 
ATOM   12313 O O   . ASN D 1 339 ? 137.415 130.969 146.309 1.00 69.04 ? 339 ASN D O   1 
ATOM   12314 C CB  . ASN D 1 339 ? 135.050 130.998 144.595 1.00 69.04 ? 339 ASN D CB  1 
ATOM   12315 C CG  . ASN D 1 339 ? 134.753 129.536 144.519 1.00 69.04 ? 339 ASN D CG  1 
ATOM   12316 O OD1 . ASN D 1 339 ? 135.630 128.700 144.730 1.00 69.04 ? 339 ASN D OD1 1 
ATOM   12317 N ND2 . ASN D 1 339 ? 133.508 129.208 144.200 1.00 69.04 ? 339 ASN D ND2 1 
ATOM   12318 N N   . TRP D 1 340 ? 136.005 130.282 147.913 1.00 69.10 ? 340 TRP D N   1 
ATOM   12319 C CA  . TRP D 1 340 ? 137.010 129.564 148.681 1.00 69.10 ? 340 TRP D CA  1 
ATOM   12320 C C   . TRP D 1 340 ? 136.836 128.074 148.449 1.00 69.10 ? 340 TRP D C   1 
ATOM   12321 O O   . TRP D 1 340 ? 135.746 127.611 148.122 1.00 69.10 ? 340 TRP D O   1 
ATOM   12322 C CB  . TRP D 1 340 ? 136.896 129.858 150.175 1.00 69.10 ? 340 TRP D CB  1 
ATOM   12323 C CG  . TRP D 1 340 ? 136.746 131.298 150.492 1.00 69.10 ? 340 TRP D CG  1 
ATOM   12324 C CD1 . TRP D 1 340 ? 137.742 132.198 150.685 1.00 69.10 ? 340 TRP D CD1 1 
ATOM   12325 C CD2 . TRP D 1 340 ? 135.522 132.011 150.653 1.00 69.10 ? 340 TRP D CD2 1 
ATOM   12326 N NE1 . TRP D 1 340 ? 137.216 133.430 150.960 1.00 69.10 ? 340 TRP D NE1 1 
ATOM   12327 C CE2 . TRP D 1 340 ? 135.851 133.339 150.946 1.00 69.10 ? 340 TRP D CE2 1 
ATOM   12328 C CE3 . TRP D 1 340 ? 134.180 131.653 150.577 1.00 69.10 ? 340 TRP D CE3 1 
ATOM   12329 C CZ2 . TRP D 1 340 ? 134.891 134.309 151.164 1.00 69.10 ? 340 TRP D CZ2 1 
ATOM   12330 C CZ3 . TRP D 1 340 ? 133.231 132.614 150.792 1.00 69.10 ? 340 TRP D CZ3 1 
ATOM   12331 C CH2 . TRP D 1 340 ? 133.586 133.926 151.083 1.00 69.10 ? 340 TRP D CH2 1 
ATOM   12332 N N   . GLU D 1 341 ? 137.913 127.323 148.628 1.00 74.05 ? 341 GLU D N   1 
ATOM   12333 C CA  . GLU D 1 341 ? 137.904 125.908 148.296 1.00 74.05 ? 341 GLU D CA  1 
ATOM   12334 C C   . GLU D 1 341 ? 138.577 125.097 149.389 1.00 74.05 ? 341 GLU D C   1 
ATOM   12335 O O   . GLU D 1 341 ? 139.650 125.472 149.868 1.00 74.05 ? 341 GLU D O   1 
ATOM   12336 C CB  . GLU D 1 341 ? 138.622 125.653 146.977 1.00 74.05 ? 341 GLU D CB  1 
ATOM   12337 C CG  . GLU D 1 341 ? 138.469 124.241 146.470 1.00 74.05 ? 341 GLU D CG  1 
ATOM   12338 C CD  . GLU D 1 341 ? 139.209 124.020 145.180 1.00 74.05 ? 341 GLU D CD  1 
ATOM   12339 O OE1 . GLU D 1 341 ? 140.009 124.895 144.796 1.00 74.05 ? 341 GLU D OE1 1 
ATOM   12340 O OE2 . GLU D 1 341 ? 138.949 122.997 144.533 1.00 74.05 ? 341 GLU D OE2 1 
ATOM   12341 N N   . MET D 1 342 ? 137.964 123.963 149.732 1.00 75.47 ? 342 MET D N   1 
ATOM   12342 C CA  . MET D 1 342 ? 138.441 123.049 150.759 1.00 75.47 ? 342 MET D CA  1 
ATOM   12343 C C   . MET D 1 342 ? 138.684 121.678 150.143 1.00 75.47 ? 342 MET D C   1 
ATOM   12344 O O   . MET D 1 342 ? 137.793 121.118 149.487 1.00 75.47 ? 342 MET D O   1 
ATOM   12345 C CB  . MET D 1 342 ? 137.429 122.937 151.896 1.00 75.47 ? 342 MET D CB  1 
ATOM   12346 C CG  . MET D 1 342 ? 136.850 124.258 152.317 1.00 75.47 ? 342 MET D CG  1 
ATOM   12347 S SD  . MET D 1 342 ? 135.497 124.065 153.475 1.00 75.47 ? 342 MET D SD  1 
ATOM   12348 C CE  . MET D 1 342 ? 134.476 122.921 152.577 1.00 75.47 ? 342 MET D CE  1 
ATOM   12349 N N   . SER D 1 343 ? 139.884 121.147 150.364 1.00 80.44 ? 343 SER D N   1 
ATOM   12350 C CA  . SER D 1 343 ? 140.317 119.869 149.825 1.00 80.44 ? 343 SER D CA  1 
ATOM   12351 C C   . SER D 1 343 ? 140.081 118.759 150.839 1.00 80.44 ? 343 SER D C   1 
ATOM   12352 O O   . SER D 1 343 ? 139.857 119.011 152.024 1.00 80.44 ? 343 SER D O   1 
ATOM   12353 C CB  . SER D 1 343 ? 141.792 119.919 149.440 1.00 80.44 ? 343 SER D CB  1 
ATOM   12354 O OG  . SER D 1 343 ? 142.238 118.661 148.971 1.00 80.44 ? 343 SER D OG  1 
ATOM   12355 N N   . ALA D 1 344 ? 140.145 117.515 150.358 1.00 81.64 ? 344 ALA D N   1 
ATOM   12356 C CA  . ALA D 1 344 ? 139.825 116.356 151.184 1.00 81.64 ? 344 ALA D CA  1 
ATOM   12357 C C   . ALA D 1 344 ? 141.046 115.788 151.891 1.00 81.64 ? 344 ALA D C   1 
ATOM   12358 O O   . ALA D 1 344 ? 140.982 115.471 153.084 1.00 81.64 ? 344 ALA D O   1 
ATOM   12359 C CB  . ALA D 1 344 ? 139.174 115.270 150.327 1.00 81.64 ? 344 ALA D CB  1 
ATOM   12360 N N   . LYS D 1 345 ? 142.161 115.662 151.182 1.00 86.92 ? 345 LYS D N   1 
ATOM   12361 C CA  . LYS D 1 345 ? 143.328 115.004 151.748 1.00 86.92 ? 345 LYS D CA  1 
ATOM   12362 C C   . LYS D 1 345 ? 144.036 115.867 152.782 1.00 86.92 ? 345 LYS D C   1 
ATOM   12363 O O   . LYS D 1 345 ? 144.660 115.332 153.705 1.00 86.92 ? 345 LYS D O   1 
ATOM   12364 C CB  . LYS D 1 345 ? 144.300 114.624 150.631 1.00 86.92 ? 345 LYS D CB  1 
ATOM   12365 C CG  . LYS D 1 345 ? 144.372 115.656 149.524 1.00 86.92 ? 345 LYS D CG  1 
ATOM   12366 C CD  . LYS D 1 345 ? 145.322 115.224 148.423 1.00 86.92 ? 345 LYS D CD  1 
ATOM   12367 C CE  . LYS D 1 345 ? 146.771 115.369 148.850 1.00 86.92 ? 345 LYS D CE  1 
ATOM   12368 N NZ  . LYS D 1 345 ? 147.129 116.788 149.120 1.00 86.92 ? 345 LYS D NZ  1 
ATOM   12369 N N   . ASP D 1 346 ? 143.956 117.187 152.655 1.00 89.65 ? 346 ASP D N   1 
ATOM   12370 C CA  . ASP D 1 346 ? 144.707 118.090 153.516 1.00 89.65 ? 346 ASP D CA  1 
ATOM   12371 C C   . ASP D 1 346 ? 143.767 118.992 154.301 1.00 89.65 ? 346 ASP D C   1 
ATOM   12372 O O   . ASP D 1 346 ? 142.543 118.881 154.214 1.00 89.65 ? 346 ASP D O   1 
ATOM   12373 C CB  . ASP D 1 346 ? 145.678 118.945 152.699 1.00 89.65 ? 346 ASP D CB  1 
ATOM   12374 C CG  . ASP D 1 346 ? 146.756 118.126 152.038 1.00 89.65 ? 346 ASP D CG  1 
ATOM   12375 O OD1 . ASP D 1 346 ? 146.881 116.931 152.373 1.00 89.65 ? 346 ASP D OD1 1 
ATOM   12376 O OD2 . ASP D 1 346 ? 147.486 118.675 151.188 1.00 89.65 ? 346 ASP D OD2 1 
ATOM   12377 N N   . SER D 1 347 ? 144.364 119.895 155.074 1.00 88.06 ? 347 SER D N   1 
ATOM   12378 C CA  . SER D 1 347 ? 143.630 120.926 155.802 1.00 88.06 ? 347 SER D CA  1 
ATOM   12379 C C   . SER D 1 347 ? 144.033 122.290 155.246 1.00 88.06 ? 347 SER D C   1 
ATOM   12380 O O   . SER D 1 347 ? 144.902 122.987 155.771 1.00 88.06 ? 347 SER D O   1 
ATOM   12381 C CB  . SER D 1 347 ? 143.906 120.823 157.298 1.00 88.06 ? 347 SER D CB  1 
ATOM   12382 O OG  . SER D 1 347 ? 143.785 119.483 157.737 1.00 88.06 ? 347 SER D OG  1 
ATOM   12383 N N   . SER D 1 348 ? 143.366 122.670 154.163 1.00 84.39 ? 348 SER D N   1 
ATOM   12384 C CA  . SER D 1 348 ? 143.667 123.900 153.452 1.00 84.39 ? 348 SER D CA  1 
ATOM   12385 C C   . SER D 1 348 ? 142.386 124.433 152.840 1.00 84.39 ? 348 SER D C   1 
ATOM   12386 O O   . SER D 1 348 ? 141.456 123.672 152.570 1.00 84.39 ? 348 SER D O   1 
ATOM   12387 C CB  . SER D 1 348 ? 144.723 123.674 152.359 1.00 84.39 ? 348 SER D CB  1 
ATOM   12388 O OG  . SER D 1 348 ? 144.921 124.839 151.581 1.00 84.39 ? 348 SER D OG  1 
ATOM   12389 N N   . VAL D 1 349 ? 142.337 125.744 152.643 1.00 77.02 ? 349 VAL D N   1 
ATOM   12390 C CA  . VAL D 1 349 ? 141.242 126.390 151.935 1.00 77.02 ? 349 VAL D CA  1 
ATOM   12391 C C   . VAL D 1 349 ? 141.795 127.621 151.241 1.00 77.02 ? 349 VAL D C   1 
ATOM   12392 O O   . VAL D 1 349 ? 142.497 128.428 151.858 1.00 77.02 ? 349 VAL D O   1 
ATOM   12393 C CB  . VAL D 1 349 ? 140.079 126.751 152.874 1.00 77.02 ? 349 VAL D CB  1 
ATOM   12394 C CG1 . VAL D 1 349 ? 140.595 127.432 154.118 1.00 77.02 ? 349 VAL D CG1 1 
ATOM   12395 C CG2 . VAL D 1 349 ? 139.087 127.637 152.153 1.00 77.02 ? 349 VAL D CG2 1 
ATOM   12396 N N   . ALA D 1 350 ? 141.495 127.753 149.956 1.00 75.22 ? 350 ALA D N   1 
ATOM   12397 C CA  . ALA D 1 350 ? 142.129 128.751 149.108 1.00 75.22 ? 350 ALA D CA  1 
ATOM   12398 C C   . ALA D 1 350 ? 141.088 129.648 148.447 1.00 75.22 ? 350 ALA D C   1 
ATOM   12399 O O   . ALA D 1 350 ? 140.007 129.183 148.084 1.00 75.22 ? 350 ALA D O   1 
ATOM   12400 C CB  . ALA D 1 350 ? 142.999 128.089 148.029 1.00 75.22 ? 350 ALA D CB  1 
ATOM   12401 N N   . PRO D 1 351 ? 141.393 130.938 148.281 1.00 70.55 ? 351 PRO D N   1 
ATOM   12402 C CA  . PRO D 1 351 ? 140.413 131.855 147.693 1.00 70.55 ? 351 PRO D CA  1 
ATOM   12403 C C   . PRO D 1 351 ? 140.573 132.041 146.192 1.00 70.55 ? 351 PRO D C   1 
ATOM   12404 O O   . PRO D 1 351 ? 141.582 131.653 145.597 1.00 70.55 ? 351 PRO D O   1 
ATOM   12405 C CB  . PRO D 1 351 ? 140.693 133.155 148.443 1.00 70.55 ? 351 PRO D CB  1 
ATOM   12406 C CG  . PRO D 1 351 ? 142.160 133.114 148.647 1.00 70.55 ? 351 PRO D CG  1 
ATOM   12407 C CD  . PRO D 1 351 ? 142.578 131.664 148.751 1.00 70.55 ? 351 PRO D CD  1 
ATOM   12408 N N   . LYS D 1 352 ? 139.553 132.636 145.578 1.00 69.03 ? 352 LYS D N   1 
ATOM   12409 C CA  . LYS D 1 352 ? 139.547 132.959 144.155 1.00 69.03 ? 352 LYS D CA  1 
ATOM   12410 C C   . LYS D 1 352 ? 138.546 134.082 143.942 1.00 69.03 ? 352 LYS D C   1 
ATOM   12411 O O   . LYS D 1 352 ? 137.347 133.902 144.183 1.00 69.03 ? 352 LYS D O   1 
ATOM   12412 C CB  . LYS D 1 352 ? 139.191 131.739 143.319 1.00 69.03 ? 352 LYS D CB  1 
ATOM   12413 C CG  . LYS D 1 352 ? 138.903 132.031 141.875 1.00 69.03 ? 352 LYS D CG  1 
ATOM   12414 C CD  . LYS D 1 352 ? 138.436 130.774 141.205 1.00 69.03 ? 352 LYS D CD  1 
ATOM   12415 C CE  . LYS D 1 352 ? 137.686 131.070 139.942 1.00 69.03 ? 352 LYS D CE  1 
ATOM   12416 N NZ  . LYS D 1 352 ? 136.887 129.897 139.505 1.00 69.03 ? 352 LYS D NZ  1 
ATOM   12417 N N   . LEU D 1 353 ? 139.040 135.227 143.496 1.00 69.74 ? 353 LEU D N   1 
ATOM   12418 C CA  . LEU D 1 353 ? 138.292 136.470 143.437 1.00 69.74 ? 353 LEU D CA  1 
ATOM   12419 C C   . LEU D 1 353 ? 137.864 136.763 142.004 1.00 69.74 ? 353 LEU D C   1 
ATOM   12420 O O   . LEU D 1 353 ? 138.434 136.241 141.048 1.00 69.74 ? 353 LEU D O   1 
ATOM   12421 C CB  . LEU D 1 353 ? 139.155 137.601 144.002 1.00 69.74 ? 353 LEU D CB  1 
ATOM   12422 C CG  . LEU D 1 353 ? 138.813 139.086 144.033 1.00 69.74 ? 353 LEU D CG  1 
ATOM   12423 C CD1 . LEU D 1 353 ? 137.413 139.351 144.508 1.00 69.74 ? 353 LEU D CD1 1 
ATOM   12424 C CD2 . LEU D 1 353 ? 139.776 139.710 144.994 1.00 69.74 ? 353 LEU D CD2 1 
ATOM   12425 N N   . TYR D 1 354 ? 136.830 137.578 141.866 1.00 68.43 ? 354 TYR D N   1 
ATOM   12426 C CA  . TYR D 1 354 ? 136.265 137.947 140.580 1.00 68.43 ? 354 TYR D CA  1 
ATOM   12427 C C   . TYR D 1 354 ? 136.020 139.442 140.581 1.00 68.43 ? 354 TYR D C   1 
ATOM   12428 O O   . TYR D 1 354 ? 135.467 139.973 141.548 1.00 68.43 ? 354 TYR D O   1 
ATOM   12429 C CB  . TYR D 1 354 ? 134.912 137.277 140.322 1.00 68.43 ? 354 TYR D CB  1 
ATOM   12430 C CG  . TYR D 1 354 ? 134.866 135.775 140.291 1.00 68.43 ? 354 TYR D CG  1 
ATOM   12431 C CD1 . TYR D 1 354 ? 134.982 135.041 141.453 1.00 68.43 ? 354 TYR D CD1 1 
ATOM   12432 C CD2 . TYR D 1 354 ? 134.677 135.093 139.104 1.00 68.43 ? 354 TYR D CD2 1 
ATOM   12433 C CE1 . TYR D 1 354 ? 134.923 133.669 141.438 1.00 68.43 ? 354 TYR D CE1 1 
ATOM   12434 C CE2 . TYR D 1 354 ? 134.608 133.721 139.080 1.00 68.43 ? 354 TYR D CE2 1 
ATOM   12435 C CZ  . TYR D 1 354 ? 134.736 133.013 140.254 1.00 68.43 ? 354 TYR D CZ  1 
ATOM   12436 O OH  . TYR D 1 354 ? 134.677 131.641 140.255 1.00 68.43 ? 354 TYR D OH  1 
ATOM   12437 N N   . LEU D 1 355 ? 136.372 140.108 139.488 1.00 66.92 ? 355 LEU D N   1 
ATOM   12438 C CA  . LEU D 1 355 ? 135.901 141.460 139.235 1.00 66.92 ? 355 LEU D CA  1 
ATOM   12439 C C   . LEU D 1 355 ? 134.857 141.394 138.135 1.00 66.92 ? 355 LEU D C   1 
ATOM   12440 O O   . LEU D 1 355 ? 135.144 140.902 137.036 1.00 66.92 ? 355 LEU D O   1 
ATOM   12441 C CB  . LEU D 1 355 ? 137.042 142.388 138.837 1.00 66.92 ? 355 LEU D CB  1 
ATOM   12442 C CG  . LEU D 1 355 ? 138.111 142.636 139.890 1.00 66.92 ? 355 LEU D CG  1 
ATOM   12443 C CD1 . LEU D 1 355 ? 138.794 143.957 139.616 1.00 66.92 ? 355 LEU D CD1 1 
ATOM   12444 C CD2 . LEU D 1 355 ? 137.515 142.622 141.273 1.00 66.92 ? 355 LEU D CD2 1 
ATOM   12445 N N   . THR D 1 356 ? 133.648 141.866 138.429 1.00 65.30 ? 356 THR D N   1 
ATOM   12446 C CA  . THR D 1 356 ? 132.616 141.912 137.410 1.00 65.30 ? 356 THR D CA  1 
ATOM   12447 C C   . THR D 1 356 ? 132.833 143.119 136.508 1.00 65.30 ? 356 THR D C   1 
ATOM   12448 O O   . THR D 1 356 ? 132.997 144.244 136.988 1.00 65.30 ? 356 THR D O   1 
ATOM   12449 C CB  . THR D 1 356 ? 131.244 141.970 138.060 1.00 65.30 ? 356 THR D CB  1 
ATOM   12450 O OG1 . THR D 1 356 ? 131.135 140.910 139.012 1.00 65.30 ? 356 THR D OG1 1 
ATOM   12451 C CG2 . THR D 1 356 ? 130.163 141.819 137.021 1.00 65.30 ? 356 THR D CG2 1 
ATOM   12452 N N   . VAL D 1 357 ? 132.844 142.882 135.198 1.00 66.79 ? 357 VAL D N   1 
ATOM   12453 C CA  . VAL D 1 357 ? 133.098 143.913 134.203 1.00 66.79 ? 357 VAL D CA  1 
ATOM   12454 C C   . VAL D 1 357 ? 131.973 143.974 133.176 1.00 66.79 ? 357 VAL D C   1 
ATOM   12455 O O   . VAL D 1 357 ? 132.189 144.369 132.035 1.00 66.79 ? 357 VAL D O   1 
ATOM   12456 C CB  . VAL D 1 357 ? 134.459 143.696 133.519 1.00 66.79 ? 357 VAL D CB  1 
ATOM   12457 C CG1 . VAL D 1 357 ? 135.559 143.728 134.544 1.00 66.79 ? 357 VAL D CG1 1 
ATOM   12458 C CG2 . VAL D 1 357 ? 134.480 142.383 132.776 1.00 66.79 ? 357 VAL D CG2 1 
ATOM   12459 N N   . ILE D 1 358 ? 130.766 143.585 133.580 1.00 69.53 ? 358 ILE D N   1 
ATOM   12460 C CA  . ILE D 1 358 ? 129.645 143.525 132.651 1.00 69.53 ? 358 ILE D CA  1 
ATOM   12461 C C   . ILE D 1 358 ? 129.353 144.887 132.041 1.00 69.53 ? 358 ILE D C   1 
ATOM   12462 O O   . ILE D 1 358 ? 128.823 144.975 130.927 1.00 69.53 ? 358 ILE D O   1 
ATOM   12463 C CB  . ILE D 1 358 ? 128.411 142.950 133.370 1.00 69.53 ? 358 ILE D CB  1 
ATOM   12464 C CG1 . ILE D 1 358 ? 127.226 142.841 132.414 1.00 69.53 ? 358 ILE D CG1 1 
ATOM   12465 C CG2 . ILE D 1 358 ? 128.061 143.781 134.578 1.00 69.53 ? 358 ILE D CG2 1 
ATOM   12466 C CD1 . ILE D 1 358 ? 126.071 142.079 132.976 1.00 69.53 ? 358 ILE D CD1 1 
ATOM   12467 N N   . GLU D 1 359 ? 129.702 145.967 132.737 1.00 75.53 ? 359 GLU D N   1 
ATOM   12468 C CA  . GLU D 1 359 ? 129.290 147.304 132.335 1.00 75.53 ? 359 GLU D CA  1 
ATOM   12469 C C   . GLU D 1 359 ? 130.475 148.200 132.016 1.00 75.53 ? 359 GLU D C   1 
ATOM   12470 O O   . GLU D 1 359 ? 130.504 149.353 132.448 1.00 75.53 ? 359 GLU D O   1 
ATOM   12471 C CB  . GLU D 1 359 ? 128.442 147.946 133.431 1.00 75.53 ? 359 GLU D CB  1 
ATOM   12472 C CG  . GLU D 1 359 ? 127.167 147.200 133.763 1.00 75.53 ? 359 GLU D CG  1 
ATOM   12473 C CD  . GLU D 1 359 ? 125.934 147.877 133.206 1.00 75.53 ? 359 GLU D CD  1 
ATOM   12474 O OE1 . GLU D 1 359 ? 126.079 148.725 132.298 1.00 75.53 ? 359 GLU D OE1 1 
ATOM   12475 O OE2 . GLU D 1 359 ? 124.822 147.570 133.687 1.00 75.53 ? 359 GLU D OE2 1 
ATOM   12476 N N   . ASP D 1 360 ? 131.451 147.699 131.274 1.00 78.38 ? 360 ASP D N   1 
ATOM   12477 C CA  . ASP D 1 360 ? 132.674 148.437 131.023 1.00 78.38 ? 360 ASP D CA  1 
ATOM   12478 C C   . ASP D 1 360 ? 132.972 148.500 129.526 1.00 78.38 ? 360 ASP D C   1 
ATOM   12479 O O   . ASP D 1 360 ? 132.235 147.972 128.693 1.00 78.38 ? 360 ASP D O   1 
ATOM   12480 C CB  . ASP D 1 360 ? 133.827 147.799 131.795 1.00 78.38 ? 360 ASP D CB  1 
ATOM   12481 C CG  . ASP D 1 360 ? 133.670 147.944 133.292 1.00 78.38 ? 360 ASP D CG  1 
ATOM   12482 O OD1 . ASP D 1 360 ? 133.032 148.921 133.730 1.00 78.38 ? 360 ASP D OD1 1 
ATOM   12483 O OD2 . ASP D 1 360 ? 134.189 147.088 134.033 1.00 78.38 ? 360 ASP D OD2 1 
ATOM   12484 N N   . TYR D 1 361 ? 134.077 149.159 129.185 1.00 80.69 ? 361 TYR D N   1 
ATOM   12485 C CA  . TYR D 1 361 ? 134.508 149.276 127.798 1.00 80.69 ? 361 TYR D CA  1 
ATOM   12486 C C   . TYR D 1 361 ? 135.200 147.996 127.359 1.00 80.69 ? 361 TYR D C   1 
ATOM   12487 O O   . TYR D 1 361 ? 136.292 147.684 127.844 1.00 80.69 ? 361 TYR D O   1 
ATOM   12488 C CB  . TYR D 1 361 ? 135.457 150.455 127.625 1.00 80.69 ? 361 TYR D CB  1 
ATOM   12489 C CG  . TYR D 1 361 ? 134.771 151.781 127.513 1.00 80.69 ? 361 TYR D CG  1 
ATOM   12490 C CD1 . TYR D 1 361 ? 134.304 152.232 126.294 1.00 80.69 ? 361 TYR D CD1 1 
ATOM   12491 C CD2 . TYR D 1 361 ? 134.586 152.582 128.624 1.00 80.69 ? 361 TYR D CD2 1 
ATOM   12492 C CE1 . TYR D 1 361 ? 133.672 153.441 126.180 1.00 80.69 ? 361 TYR D CE1 1 
ATOM   12493 C CE2 . TYR D 1 361 ? 133.957 153.799 128.520 1.00 80.69 ? 361 TYR D CE2 1 
ATOM   12494 C CZ  . TYR D 1 361 ? 133.498 154.222 127.294 1.00 80.69 ? 361 TYR D CZ  1 
ATOM   12495 O OH  . TYR D 1 361 ? 132.866 155.436 127.174 1.00 80.69 ? 361 TYR D OH  1 
ATOM   12496 N N   . ASP D 1 362 ? 134.575 147.264 126.432 1.00 74.96 ? 362 ASP D N   1 
ATOM   12497 C CA  . ASP D 1 362 ? 135.229 146.088 125.879 1.00 74.96 ? 362 ASP D CA  1 
ATOM   12498 C C   . ASP D 1 362 ? 136.620 146.426 125.389 1.00 74.96 ? 362 ASP D C   1 
ATOM   12499 O O   . ASP D 1 362 ? 137.538 145.617 125.531 1.00 74.96 ? 362 ASP D O   1 
ATOM   12500 C CB  . ASP D 1 362 ? 134.412 145.491 124.741 1.00 74.96 ? 362 ASP D CB  1 
ATOM   12501 C CG  . ASP D 1 362 ? 133.175 144.793 125.223 1.00 74.96 ? 362 ASP D CG  1 
ATOM   12502 O OD1 . ASP D 1 362 ? 133.147 144.368 126.389 1.00 74.96 ? 362 ASP D OD1 1 
ATOM   12503 O OD2 . ASP D 1 362 ? 132.221 144.668 124.436 1.00 74.96 ? 362 ASP D OD2 1 
ATOM   12504 N N   . ALA D 1 363 ? 136.804 147.615 124.820 1.00 77.52 ? 363 ALA D N   1 
ATOM   12505 C CA  . ALA D 1 363 ? 138.145 148.043 124.452 1.00 77.52 ? 363 ALA D CA  1 
ATOM   12506 C C   . ALA D 1 363 ? 139.032 148.146 125.684 1.00 77.52 ? 363 ALA D C   1 
ATOM   12507 O O   . ALA D 1 363 ? 140.152 147.625 125.702 1.00 77.52 ? 363 ALA D O   1 
ATOM   12508 C CB  . ALA D 1 363 ? 138.088 149.376 123.712 1.00 77.52 ? 363 ALA D CB  1 
ATOM   12509 N N   . TYR D 1 364 ? 138.533 148.791 126.740 1.00 80.22 ? 364 TYR D N   1 
ATOM   12510 C CA  . TYR D 1 364 ? 139.331 148.934 127.954 1.00 80.22 ? 364 TYR D CA  1 
ATOM   12511 C C   . TYR D 1 364 ? 139.519 147.597 128.653 1.00 80.22 ? 364 TYR D C   1 
ATOM   12512 O O   . TYR D 1 364 ? 140.621 147.287 129.119 1.00 80.22 ? 364 TYR D O   1 
ATOM   12513 C CB  . TYR D 1 364 ? 138.679 149.935 128.902 1.00 80.22 ? 364 TYR D CB  1 
ATOM   12514 C CG  . TYR D 1 364 ? 138.955 151.375 128.558 1.00 80.22 ? 364 TYR D CG  1 
ATOM   12515 C CD1 . TYR D 1 364 ? 140.184 151.760 128.050 1.00 80.22 ? 364 TYR D CD1 1 
ATOM   12516 C CD2 . TYR D 1 364 ? 137.985 152.350 128.742 1.00 80.22 ? 364 TYR D CD2 1 
ATOM   12517 C CE1 . TYR D 1 364 ? 140.440 153.073 127.735 1.00 80.22 ? 364 TYR D CE1 1 
ATOM   12518 C CE2 . TYR D 1 364 ? 138.228 153.663 128.428 1.00 80.22 ? 364 TYR D CE2 1 
ATOM   12519 C CZ  . TYR D 1 364 ? 139.459 154.022 127.925 1.00 80.22 ? 364 TYR D CZ  1 
ATOM   12520 O OH  . TYR D 1 364 ? 139.709 155.336 127.610 1.00 80.22 ? 364 TYR D OH  1 
ATOM   12521 N N   . VAL D 1 365 ? 138.452 146.802 128.759 1.00 74.75 ? 365 VAL D N   1 
ATOM   12522 C CA  . VAL D 1 365 ? 138.572 145.489 129.385 1.00 74.75 ? 365 VAL D CA  1 
ATOM   12523 C C   . VAL D 1 365 ? 139.604 144.655 128.646 1.00 74.75 ? 365 VAL D C   1 
ATOM   12524 O O   . VAL D 1 365 ? 140.495 144.054 129.255 1.00 74.75 ? 365 VAL D O   1 
ATOM   12525 C CB  . VAL D 1 365 ? 137.208 144.781 129.424 1.00 74.75 ? 365 VAL D CB  1 
ATOM   12526 C CG1 . VAL D 1 365 ? 137.360 143.408 130.017 1.00 74.75 ? 365 VAL D CG1 1 
ATOM   12527 C CG2 . VAL D 1 365 ? 136.219 145.586 130.219 1.00 74.75 ? 365 VAL D CG2 1 
ATOM   12528 N N   . SER D 1 366 ? 139.498 144.612 127.319 1.00 73.58 ? 366 SER D N   1 
ATOM   12529 C CA  . SER D 1 366 ? 140.457 143.872 126.515 1.00 73.58 ? 366 SER D CA  1 
ATOM   12530 C C   . SER D 1 366 ? 141.865 144.399 126.715 1.00 73.58 ? 366 SER D C   1 
ATOM   12531 O O   . SER D 1 366 ? 142.811 143.617 126.819 1.00 73.58 ? 366 SER D O   1 
ATOM   12532 C CB  . SER D 1 366 ? 140.081 143.951 125.043 1.00 73.58 ? 366 SER D CB  1 
ATOM   12533 O OG  . SER D 1 366 ? 138.822 143.363 124.815 1.00 73.58 ? 366 SER D OG  1 
ATOM   12534 N N   . SER D 1 367 ? 142.031 145.722 126.751 1.00 76.10 ? 367 SER D N   1 
ATOM   12535 C CA  . SER D 1 367 ? 143.364 146.281 126.914 1.00 76.10 ? 367 SER D CA  1 
ATOM   12536 C C   . SER D 1 367 ? 143.962 145.874 128.249 1.00 76.10 ? 367 SER D C   1 
ATOM   12537 O O   . SER D 1 367 ? 145.143 145.518 128.332 1.00 76.10 ? 367 SER D O   1 
ATOM   12538 C CB  . SER D 1 367 ? 143.314 147.799 126.789 1.00 76.10 ? 367 SER D CB  1 
ATOM   12539 O OG  . SER D 1 367 ? 144.621 148.339 126.735 1.00 76.10 ? 367 SER D OG  1 
ATOM   12540 N N   . ALA D 1 368 ? 143.150 145.904 129.304 1.00 76.16 ? 368 ALA D N   1 
ATOM   12541 C CA  . ALA D 1 368 ? 143.634 145.489 130.613 1.00 76.16 ? 368 ALA D CA  1 
ATOM   12542 C C   . ALA D 1 368 ? 143.992 144.012 130.620 1.00 76.16 ? 368 ALA D C   1 
ATOM   12543 O O   . ALA D 1 368 ? 145.008 143.613 131.199 1.00 76.16 ? 368 ALA D O   1 
ATOM   12544 C CB  . ALA D 1 368 ? 142.588 145.792 131.680 1.00 76.16 ? 368 ALA D CB  1 
ATOM   12545 N N   . ILE D 1 369 ? 143.175 143.182 129.977 1.00 74.93 ? 369 ILE D N   1 
ATOM   12546 C CA  . ILE D 1 369 ? 143.483 141.759 129.929 1.00 74.93 ? 369 ILE D CA  1 
ATOM   12547 C C   . ILE D 1 369 ? 144.798 141.534 129.200 1.00 74.93 ? 369 ILE D C   1 
ATOM   12548 O O   . ILE D 1 369 ? 145.685 140.817 129.681 1.00 74.93 ? 369 ILE D O   1 
ATOM   12549 C CB  . ILE D 1 369 ? 142.336 140.973 129.276 1.00 74.93 ? 369 ILE D CB  1 
ATOM   12550 C CG1 . ILE D 1 369 ? 141.064 141.103 130.103 1.00 74.93 ? 369 ILE D CG1 1 
ATOM   12551 C CG2 . ILE D 1 369 ? 142.712 139.520 129.160 1.00 74.93 ? 369 ILE D CG2 1 
ATOM   12552 C CD1 . ILE D 1 369 ? 139.909 140.323 129.549 1.00 74.93 ? 369 ILE D CD1 1 
ATOM   12553 N N   . VAL D 1 370 ? 144.960 142.170 128.043 1.00 76.54 ? 370 VAL D N   1 
ATOM   12554 C CA  . VAL D 1 370 ? 146.130 141.887 127.229 1.00 76.54 ? 370 VAL D CA  1 
ATOM   12555 C C   . VAL D 1 370 ? 147.392 142.445 127.873 1.00 76.54 ? 370 VAL D C   1 
ATOM   12556 O O   . VAL D 1 370 ? 148.456 141.823 127.798 1.00 76.54 ? 370 VAL D O   1 
ATOM   12557 C CB  . VAL D 1 370 ? 145.937 142.398 125.791 1.00 76.54 ? 370 VAL D CB  1 
ATOM   12558 C CG1 . VAL D 1 370 ? 144.646 141.865 125.218 1.00 76.54 ? 370 VAL D CG1 1 
ATOM   12559 C CG2 . VAL D 1 370 ? 145.964 143.904 125.742 1.00 76.54 ? 370 VAL D CG2 1 
ATOM   12560 N N   . ASP D 1 371 ? 147.310 143.591 128.556 1.00 79.16 ? 371 ASP D N   1 
ATOM   12561 C CA  . ASP D 1 371 ? 148.554 144.086 129.133 1.00 79.16 ? 371 ASP D CA  1 
ATOM   12562 C C   . ASP D 1 371 ? 148.858 143.438 130.481 1.00 79.16 ? 371 ASP D C   1 
ATOM   12563 O O   . ASP D 1 371 ? 150.029 143.322 130.853 1.00 79.16 ? 371 ASP D O   1 
ATOM   12564 C CB  . ASP D 1 371 ? 148.549 145.613 129.232 1.00 79.16 ? 371 ASP D CB  1 
ATOM   12565 C CG  . ASP D 1 371 ? 147.504 146.145 130.172 1.00 79.16 ? 371 ASP D CG  1 
ATOM   12566 O OD1 . ASP D 1 371 ? 146.692 145.353 130.661 1.00 79.16 ? 371 ASP D OD1 1 
ATOM   12567 O OD2 . ASP D 1 371 ? 147.495 147.371 130.426 1.00 79.16 ? 371 ASP D OD2 1 
ATOM   12568 N N   . LEU D 1 372 ? 147.836 142.981 131.211 1.00 79.34 ? 372 LEU D N   1 
ATOM   12569 C CA  . LEU D 1 372 ? 148.074 142.078 132.330 1.00 79.34 ? 372 LEU D CA  1 
ATOM   12570 C C   . LEU D 1 372 ? 148.830 140.846 131.866 1.00 79.34 ? 372 LEU D C   1 
ATOM   12571 O O   . LEU D 1 372 ? 149.860 140.473 132.441 1.00 79.34 ? 372 LEU D O   1 
ATOM   12572 C CB  . LEU D 1 372 ? 146.745 141.675 132.961 1.00 79.34 ? 372 LEU D CB  1 
ATOM   12573 C CG  . LEU D 1 372 ? 146.831 140.671 134.107 1.00 79.34 ? 372 LEU D CG  1 
ATOM   12574 C CD1 . LEU D 1 372 ? 147.595 141.251 135.281 1.00 79.34 ? 372 LEU D CD1 1 
ATOM   12575 C CD2 . LEU D 1 372 ? 145.438 140.247 134.523 1.00 79.34 ? 372 LEU D CD2 1 
ATOM   12576 N N   . PHE D 1 373 ? 148.314 140.198 130.824 1.00 78.33 ? 373 PHE D N   1 
ATOM   12577 C CA  . PHE D 1 373 ? 149.018 139.076 130.229 1.00 78.33 ? 373 PHE D CA  1 
ATOM   12578 C C   . PHE D 1 373 ? 150.440 139.454 129.848 1.00 78.33 ? 373 PHE D C   1 
ATOM   12579 O O   . PHE D 1 373 ? 151.385 138.704 130.118 1.00 78.33 ? 373 PHE D O   1 
ATOM   12580 C CB  . PHE D 1 373 ? 148.255 138.598 129.006 1.00 78.33 ? 373 PHE D CB  1 
ATOM   12581 C CG  . PHE D 1 373 ? 147.130 137.674 129.320 1.00 78.33 ? 373 PHE D CG  1 
ATOM   12582 C CD1 . PHE D 1 373 ? 146.954 137.184 130.590 1.00 78.33 ? 373 PHE D CD1 1 
ATOM   12583 C CD2 . PHE D 1 373 ? 146.255 137.284 128.332 1.00 78.33 ? 373 PHE D CD2 1 
ATOM   12584 C CE1 . PHE D 1 373 ? 145.923 136.331 130.864 1.00 78.33 ? 373 PHE D CE1 1 
ATOM   12585 C CE2 . PHE D 1 373 ? 145.230 136.435 128.600 1.00 78.33 ? 373 PHE D CE2 1 
ATOM   12586 C CZ  . PHE D 1 373 ? 145.060 135.955 129.865 1.00 78.33 ? 373 PHE D CZ  1 
ATOM   12587 N N   . THR D 1 374 ? 150.613 140.615 129.220 1.00 80.40 ? 374 THR D N   1 
ATOM   12588 C CA  . THR D 1 374 ? 151.928 140.990 128.720 1.00 80.40 ? 374 THR D CA  1 
ATOM   12589 C C   . THR D 1 374 ? 152.919 141.173 129.856 1.00 80.40 ? 374 THR D C   1 
ATOM   12590 O O   . THR D 1 374 ? 154.057 140.699 129.776 1.00 80.40 ? 374 THR D O   1 
ATOM   12591 C CB  . THR D 1 374 ? 151.823 142.260 127.887 1.00 80.40 ? 374 THR D CB  1 
ATOM   12592 O OG1 . THR D 1 374 ? 150.986 142.000 126.755 1.00 80.40 ? 374 THR D OG1 1 
ATOM   12593 C CG2 . THR D 1 374 ? 153.195 142.698 127.412 1.00 80.40 ? 374 THR D CG2 1 
ATOM   12594 N N   . GLY D 1 375 ? 152.505 141.851 130.923 1.00 83.25 ? 375 GLY D N   1 
ATOM   12595 C CA  . GLY D 1 375 ? 153.336 141.892 132.113 1.00 83.25 ? 375 GLY D CA  1 
ATOM   12596 C C   . GLY D 1 375 ? 153.645 140.502 132.631 1.00 83.25 ? 375 GLY D C   1 
ATOM   12597 O O   . GLY D 1 375 ? 154.768 140.217 133.053 1.00 83.25 ? 375 GLY D O   1 
ATOM   12598 N N   . LEU D 1 376 ? 152.654 139.613 132.590 1.00 80.88 ? 376 LEU D N   1 
ATOM   12599 C CA  . LEU D 1 376 ? 152.864 138.232 132.998 1.00 80.88 ? 376 LEU D CA  1 
ATOM   12600 C C   . LEU D 1 376 ? 153.705 137.447 132.002 1.00 80.88 ? 376 LEU D C   1 
ATOM   12601 O O   . LEU D 1 376 ? 154.142 136.338 132.320 1.00 80.88 ? 376 LEU D O   1 
ATOM   12602 C CB  . LEU D 1 376 ? 151.520 137.546 133.193 1.00 80.88 ? 376 LEU D CB  1 
ATOM   12603 C CG  . LEU D 1 376 ? 151.462 136.700 134.453 1.00 80.88 ? 376 LEU D CG  1 
ATOM   12604 C CD1 . LEU D 1 376 ? 150.860 137.526 135.551 1.00 80.88 ? 376 LEU D CD1 1 
ATOM   12605 C CD2 . LEU D 1 376 ? 150.632 135.447 134.207 1.00 80.88 ? 376 LEU D CD2 1 
ATOM   12606 N N   . GLY D 1 377 ? 153.924 137.981 130.806 1.00 78.59 ? 377 GLY D N   1 
ATOM   12607 C CA  . GLY D 1 377 ? 154.684 137.268 129.804 1.00 78.59 ? 377 GLY D CA  1 
ATOM   12608 C C   . GLY D 1 377 ? 153.924 136.192 129.067 1.00 78.59 ? 377 GLY D C   1 
ATOM   12609 O O   . GLY D 1 377 ? 154.546 135.379 128.380 1.00 78.59 ? 377 GLY D O   1 
ATOM   12610 N N   . TRP D 1 378 ? 152.598 136.151 129.186 1.00 75.46 ? 378 TRP D N   1 
ATOM   12611 C CA  . TRP D 1 378 ? 151.787 135.160 128.479 1.00 75.46 ? 378 TRP D CA  1 
ATOM   12612 C C   . TRP D 1 378 ? 151.519 135.593 127.035 1.00 75.46 ? 378 TRP D C   1 
ATOM   12613 O O   . TRP D 1 378 ? 150.379 135.779 126.612 1.00 75.46 ? 378 TRP D O   1 
ATOM   12614 C CB  . TRP D 1 378 ? 150.481 134.924 129.225 1.00 75.46 ? 378 TRP D CB  1 
ATOM   12615 C CG  . TRP D 1 378 ? 150.594 133.991 130.380 1.00 75.46 ? 378 TRP D CG  1 
ATOM   12616 C CD1 . TRP D 1 378 ? 151.701 133.302 130.775 1.00 75.46 ? 378 TRP D CD1 1 
ATOM   12617 C CD2 . TRP D 1 378 ? 149.558 133.651 131.306 1.00 75.46 ? 378 TRP D CD2 1 
ATOM   12618 N NE1 . TRP D 1 378 ? 151.416 132.546 131.886 1.00 75.46 ? 378 TRP D NE1 1 
ATOM   12619 C CE2 . TRP D 1 378 ? 150.105 132.745 132.230 1.00 75.46 ? 378 TRP D CE2 1 
ATOM   12620 C CE3 . TRP D 1 378 ? 148.219 134.023 131.440 1.00 75.46 ? 378 TRP D CE3 1 
ATOM   12621 C CZ2 . TRP D 1 378 ? 149.359 132.210 133.277 1.00 75.46 ? 378 TRP D CZ2 1 
ATOM   12622 C CZ3 . TRP D 1 378 ? 147.481 133.489 132.476 1.00 75.46 ? 378 TRP D CZ3 1 
ATOM   12623 C CH2 . TRP D 1 378 ? 148.051 132.596 133.381 1.00 75.46 ? 378 TRP D CH2 1 
ATOM   12624 N N   . ALA D 1 379 ? 152.600 135.732 126.264 1.00 75.25 ? 379 ALA D N   1 
ATOM   12625 C CA  . ALA D 1 379 ? 152.471 136.239 124.900 1.00 75.25 ? 379 ALA D CA  1 
ATOM   12626 C C   . ALA D 1 379 ? 151.694 135.276 124.013 1.00 75.25 ? 379 ALA D C   1 
ATOM   12627 O O   . ALA D 1 379 ? 150.826 135.698 123.238 1.00 75.25 ? 379 ALA D O   1 
ATOM   12628 C CB  . ALA D 1 379 ? 153.850 136.510 124.309 1.00 75.25 ? 379 ALA D CB  1 
ATOM   12629 N N   . ALA D 1 380 ? 152.013 133.986 124.082 1.00 74.59 ? 380 ALA D N   1 
ATOM   12630 C CA  . ALA D 1 380 ? 151.214 132.999 123.371 1.00 74.59 ? 380 ALA D CA  1 
ATOM   12631 C C   . ALA D 1 380 ? 149.753 133.134 123.758 1.00 74.59 ? 380 ALA D C   1 
ATOM   12632 O O   . ALA D 1 380 ? 148.863 133.151 122.902 1.00 74.59 ? 380 ALA D O   1 
ATOM   12633 C CB  . ALA D 1 380 ? 151.728 131.594 123.673 1.00 74.59 ? 380 ALA D CB  1 
ATOM   12634 N N   . HIS D 1 381 ? 149.493 133.258 125.056 1.00 73.53 ? 381 HIS D N   1 
ATOM   12635 C CA  . HIS D 1 381 ? 148.136 133.506 125.510 1.00 73.53 ? 381 HIS D CA  1 
ATOM   12636 C C   . HIS D 1 381 ? 147.607 134.834 124.994 1.00 73.53 ? 381 HIS D C   1 
ATOM   12637 O O   . HIS D 1 381 ? 146.401 134.972 124.782 1.00 73.53 ? 381 HIS D O   1 
ATOM   12638 C CB  . HIS D 1 381 ? 148.088 133.471 127.031 1.00 73.53 ? 381 HIS D CB  1 
ATOM   12639 C CG  . HIS D 1 381 ? 148.346 132.117 127.612 1.00 73.53 ? 381 HIS D CG  1 
ATOM   12640 N ND1 . HIS D 1 381 ? 147.399 131.116 127.619 1.00 73.53 ? 381 HIS D ND1 1 
ATOM   12641 C CD2 . HIS D 1 381 ? 149.440 131.602 128.217 1.00 73.53 ? 381 HIS D CD2 1 
ATOM   12642 C CE1 . HIS D 1 381 ? 147.897 130.044 128.206 1.00 73.53 ? 381 HIS D CE1 1 
ATOM   12643 N NE2 . HIS D 1 381 ? 149.135 130.312 128.578 1.00 73.53 ? 381 HIS D NE2 1 
ATOM   12644 N N   . VAL D 1 382 ? 148.483 135.816 124.773 1.00 73.84 ? 382 VAL D N   1 
ATOM   12645 C CA  . VAL D 1 382 ? 148.030 137.106 124.255 1.00 73.84 ? 382 VAL D CA  1 
ATOM   12646 C C   . VAL D 1 382 ? 147.472 136.945 122.849 1.00 73.84 ? 382 VAL D C   1 
ATOM   12647 O O   . VAL D 1 382 ? 146.361 137.402 122.542 1.00 73.84 ? 382 VAL D O   1 
ATOM   12648 C CB  . VAL D 1 382 ? 149.173 138.137 124.281 1.00 73.84 ? 382 VAL D CB  1 
ATOM   12649 C CG1 . VAL D 1 382 ? 148.824 139.323 123.404 1.00 73.84 ? 382 VAL D CG1 1 
ATOM   12650 C CG2 . VAL D 1 382 ? 149.457 138.598 125.689 1.00 73.84 ? 382 VAL D CG2 1 
ATOM   12651 N N   . GLN D 1 383 ? 148.254 136.329 121.962 1.00 72.68 ? 383 GLN D N   1 
ATOM   12652 C CA  . GLN D 1 383 ? 147.766 136.086 120.612 1.00 72.68 ? 383 GLN D CA  1 
ATOM   12653 C C   . GLN D 1 383 ? 146.536 135.204 120.642 1.00 72.68 ? 383 GLN D C   1 
ATOM   12654 O O   . GLN D 1 383 ? 145.593 135.418 119.876 1.00 72.68 ? 383 GLN D O   1 
ATOM   12655 C CB  . GLN D 1 383 ? 148.855 135.448 119.753 1.00 72.68 ? 383 GLN D CB  1 
ATOM   12656 C CG  . GLN D 1 383 ? 150.161 136.209 119.756 1.00 72.68 ? 383 GLN D CG  1 
ATOM   12657 C CD  . GLN D 1 383 ? 149.963 137.690 119.533 1.00 72.68 ? 383 GLN D CD  1 
ATOM   12658 O OE1 . GLN D 1 383 ? 149.324 138.104 118.569 1.00 72.68 ? 383 GLN D OE1 1 
ATOM   12659 N NE2 . GLN D 1 383 ? 150.504 138.500 120.433 1.00 72.68 ? 383 GLN D NE2 1 
ATOM   12660 N N   . THR D 1 384 ? 146.529 134.206 121.523 1.00 68.62 ? 384 THR D N   1 
ATOM   12661 C CA  . THR D 1 384 ? 145.349 133.374 121.693 1.00 68.62 ? 384 THR D CA  1 
ATOM   12662 C C   . THR D 1 384 ? 144.127 134.229 121.986 1.00 68.62 ? 384 THR D C   1 
ATOM   12663 O O   . THR D 1 384 ? 143.078 134.085 121.347 1.00 68.62 ? 384 THR D O   1 
ATOM   12664 C CB  . THR D 1 384 ? 145.585 132.382 122.826 1.00 68.62 ? 384 THR D CB  1 
ATOM   12665 O OG1 . THR D 1 384 ? 146.957 131.977 122.823 1.00 68.62 ? 384 THR D OG1 1 
ATOM   12666 C CG2 . THR D 1 384 ? 144.722 131.164 122.632 1.00 68.62 ? 384 THR D CG2 1 
ATOM   12667 N N   . HIS D 1 385 ? 144.259 135.144 122.942 1.00 66.66 ? 385 HIS D N   1 
ATOM   12668 C CA  . HIS D 1 385 ? 143.129 135.957 123.359 1.00 66.66 ? 385 HIS D CA  1 
ATOM   12669 C C   . HIS D 1 385 ? 142.645 136.846 122.226 1.00 66.66 ? 385 HIS D C   1 
ATOM   12670 O O   . HIS D 1 385 ? 141.445 136.919 121.950 1.00 66.66 ? 385 HIS D O   1 
ATOM   12671 C CB  . HIS D 1 385 ? 143.515 136.799 124.565 1.00 66.66 ? 385 HIS D CB  1 
ATOM   12672 C CG  . HIS D 1 385 ? 142.411 137.680 125.039 1.00 66.66 ? 385 HIS D CG  1 
ATOM   12673 N ND1 . HIS D 1 385 ? 142.437 139.047 124.893 1.00 66.66 ? 385 HIS D ND1 1 
ATOM   12674 C CD2 . HIS D 1 385 ? 141.229 137.384 125.627 1.00 66.66 ? 385 HIS D CD2 1 
ATOM   12675 C CE1 . HIS D 1 385 ? 141.323 139.558 125.384 1.00 66.66 ? 385 HIS D CE1 1 
ATOM   12676 N NE2 . HIS D 1 385 ? 140.572 138.570 125.835 1.00 66.66 ? 385 HIS D NE2 1 
ATOM   12677 N N   . LYS D 1 386 ? 143.570 137.535 121.558 1.00 67.97 ? 386 LYS D N   1 
ATOM   12678 C CA  . LYS D 1 386 ? 143.172 138.440 120.482 1.00 67.97 ? 386 LYS D CA  1 
ATOM   12679 C C   . LYS D 1 386 ? 142.563 137.677 119.315 1.00 67.97 ? 386 LYS D C   1 
ATOM   12680 O O   . LYS D 1 386 ? 141.622 138.154 118.670 1.00 67.97 ? 386 LYS D O   1 
ATOM   12681 C CB  . LYS D 1 386 ? 144.368 139.263 120.015 1.00 67.97 ? 386 LYS D CB  1 
ATOM   12682 C CG  . LYS D 1 386 ? 144.613 140.510 120.828 1.00 67.97 ? 386 LYS D CG  1 
ATOM   12683 C CD  . LYS D 1 386 ? 146.063 140.925 120.744 1.00 67.97 ? 386 LYS D CD  1 
ATOM   12684 C CE  . LYS D 1 386 ? 146.189 142.427 120.682 1.00 67.97 ? 386 LYS D CE  1 
ATOM   12685 N NZ  . LYS D 1 386 ? 145.433 142.963 119.522 1.00 67.97 ? 386 LYS D NZ  1 
ATOM   12686 N N   . LYS D 1 387 ? 143.092 136.493 119.022 1.00 63.35 ? 387 LYS D N   1 
ATOM   12687 C CA  . LYS D 1 387 ? 142.536 135.674 117.959 1.00 63.35 ? 387 LYS D CA  1 
ATOM   12688 C C   . LYS D 1 387 ? 141.110 135.266 118.282 1.00 63.35 ? 387 LYS D C   1 
ATOM   12689 O O   . LYS D 1 387 ? 140.202 135.428 117.458 1.00 63.35 ? 387 LYS D O   1 
ATOM   12690 C CB  . LYS D 1 387 ? 143.418 134.448 117.755 1.00 63.35 ? 387 LYS D CB  1 
ATOM   12691 C CG  . LYS D 1 387 ? 142.834 133.400 116.857 1.00 63.35 ? 387 LYS D CG  1 
ATOM   12692 C CD  . LYS D 1 387 ? 143.544 132.085 117.060 1.00 63.35 ? 387 LYS D CD  1 
ATOM   12693 C CE  . LYS D 1 387 ? 145.042 132.275 117.092 1.00 63.35 ? 387 LYS D CE  1 
ATOM   12694 N NZ  . LYS D 1 387 ? 145.753 130.975 117.175 1.00 63.35 ? 387 LYS D NZ  1 
ATOM   12695 N N   . ILE D 1 388 ? 140.900 134.714 119.478 1.00 60.28 ? 388 ILE D N   1 
ATOM   12696 C CA  . ILE D 1 388 ? 139.553 134.345 119.893 1.00 60.28 ? 388 ILE D CA  1 
ATOM   12697 C C   . ILE D 1 388 ? 138.645 135.560 119.858 1.00 60.28 ? 388 ILE D C   1 
ATOM   12698 O O   . ILE D 1 388 ? 137.468 135.467 119.494 1.00 60.28 ? 388 ILE D O   1 
ATOM   12699 C CB  . ILE D 1 388 ? 139.581 133.698 121.286 1.00 60.28 ? 388 ILE D CB  1 
ATOM   12700 C CG1 . ILE D 1 388 ? 140.488 132.478 121.272 1.00 60.28 ? 388 ILE D CG1 1 
ATOM   12701 C CG2 . ILE D 1 388 ? 138.191 133.299 121.710 1.00 60.28 ? 388 ILE D CG2 1 
ATOM   12702 C CD1 . ILE D 1 388 ? 140.648 131.825 122.603 1.00 60.28 ? 388 ILE D CD1 1 
ATOM   12703 N N   . GLU D 1 389 ? 139.186 136.723 120.206 1.00 64.59 ? 389 GLU D N   1 
ATOM   12704 C CA  . GLU D 1 389 ? 138.403 137.947 120.177 1.00 64.59 ? 389 GLU D CA  1 
ATOM   12705 C C   . GLU D 1 389 ? 137.910 138.239 118.771 1.00 64.59 ? 389 GLU D C   1 
ATOM   12706 O O   . GLU D 1 389 ? 136.705 138.231 118.503 1.00 64.59 ? 389 GLU D O   1 
ATOM   12707 C CB  . GLU D 1 389 ? 139.250 139.100 120.699 1.00 64.59 ? 389 GLU D CB  1 
ATOM   12708 C CG  . GLU D 1 389 ? 138.450 140.198 121.341 1.00 64.59 ? 389 GLU D CG  1 
ATOM   12709 C CD  . GLU D 1 389 ? 139.323 141.339 121.779 1.00 64.59 ? 389 GLU D CD  1 
ATOM   12710 O OE1 . GLU D 1 389 ? 140.305 141.634 121.068 1.00 64.59 ? 389 GLU D OE1 1 
ATOM   12711 O OE2 . GLU D 1 389 ? 139.037 141.931 122.836 1.00 64.59 ? 389 GLU D OE2 1 
ATOM   12712 N N   . LYS D 1 390 ? 138.846 138.470 117.852 1.00 64.32 ? 390 LYS D N   1 
ATOM   12713 C CA  . LYS D 1 390 ? 138.489 138.855 116.492 1.00 64.32 ? 390 LYS D CA  1 
ATOM   12714 C C   . LYS D 1 390 ? 137.574 137.829 115.842 1.00 64.32 ? 390 LYS D C   1 
ATOM   12715 O O   . LYS D 1 390 ? 136.573 138.189 115.214 1.00 64.32 ? 390 LYS D O   1 
ATOM   12716 C CB  . LYS D 1 390 ? 139.753 139.045 115.662 1.00 64.32 ? 390 LYS D CB  1 
ATOM   12717 C CG  . LYS D 1 390 ? 139.495 139.482 114.245 1.00 64.32 ? 390 LYS D CG  1 
ATOM   12718 C CD  . LYS D 1 390 ? 140.791 139.599 113.472 1.00 64.32 ? 390 LYS D CD  1 
ATOM   12719 C CE  . LYS D 1 390 ? 141.516 138.268 113.435 1.00 64.32 ? 390 LYS D CE  1 
ATOM   12720 N NZ  . LYS D 1 390 ? 142.809 138.353 112.706 1.00 64.32 ? 390 LYS D NZ  1 
ATOM   12721 N N   . GLU D 1 391 ? 137.884 136.545 115.996 1.00 60.99 ? 391 GLU D N   1 
ATOM   12722 C CA  . GLU D 1 391 ? 137.113 135.524 115.301 1.00 60.99 ? 391 GLU D CA  1 
ATOM   12723 C C   . GLU D 1 391 ? 135.750 135.314 115.945 1.00 60.99 ? 391 GLU D C   1 
ATOM   12724 O O   . GLU D 1 391 ? 134.724 135.343 115.260 1.00 60.99 ? 391 GLU D O   1 
ATOM   12725 C CB  . GLU D 1 391 ? 137.902 134.217 115.267 1.00 60.99 ? 391 GLU D CB  1 
ATOM   12726 C CG  . GLU D 1 391 ? 139.157 134.296 114.418 1.00 60.99 ? 391 GLU D CG  1 
ATOM   12727 C CD  . GLU D 1 391 ? 139.964 133.021 114.448 1.00 60.99 ? 391 GLU D CD  1 
ATOM   12728 O OE1 . GLU D 1 391 ? 139.858 132.272 115.437 1.00 60.99 ? 391 GLU D OE1 1 
ATOM   12729 O OE2 . GLU D 1 391 ? 140.707 132.765 113.481 1.00 60.99 ? 391 GLU D OE2 1 
ATOM   12730 N N   . ALA D 1 392 ? 135.719 135.097 117.257 1.00 57.48 ? 392 ALA D N   1 
ATOM   12731 C CA  . ALA D 1 392 ? 134.476 134.778 117.938 1.00 57.48 ? 392 ALA D CA  1 
ATOM   12732 C C   . ALA D 1 392 ? 133.661 136.008 118.293 1.00 57.48 ? 392 ALA D C   1 
ATOM   12733 O O   . ALA D 1 392 ? 132.443 135.894 118.467 1.00 57.48 ? 392 ALA D O   1 
ATOM   12734 C CB  . ALA D 1 392 ? 134.767 133.981 119.205 1.00 57.48 ? 392 ALA D CB  1 
ATOM   12735 N N   . TYR D 1 393 ? 134.293 137.176 118.401 1.00 58.50 ? 393 TYR D N   1 
ATOM   12736 C CA  . TYR D 1 393 ? 133.612 138.405 118.799 1.00 58.50 ? 393 TYR D CA  1 
ATOM   12737 C C   . TYR D 1 393 ? 134.051 139.540 117.889 1.00 58.50 ? 393 TYR D C   1 
ATOM   12738 O O   . TYR D 1 393 ? 135.007 140.266 118.192 1.00 58.50 ? 393 TYR D O   1 
ATOM   12739 C CB  . TYR D 1 393 ? 133.892 138.727 120.260 1.00 58.50 ? 393 TYR D CB  1 
ATOM   12740 C CG  . TYR D 1 393 ? 133.442 137.631 121.183 1.00 58.50 ? 393 TYR D CG  1 
ATOM   12741 C CD1 . TYR D 1 393 ? 132.096 137.399 121.402 1.00 58.50 ? 393 TYR D CD1 1 
ATOM   12742 C CD2 . TYR D 1 393 ? 134.360 136.812 121.819 1.00 58.50 ? 393 TYR D CD2 1 
ATOM   12743 C CE1 . TYR D 1 393 ? 131.678 136.397 122.234 1.00 58.50 ? 393 TYR D CE1 1 
ATOM   12744 C CE2 . TYR D 1 393 ? 133.946 135.804 122.651 1.00 58.50 ? 393 TYR D CE2 1 
ATOM   12745 C CZ  . TYR D 1 393 ? 132.606 135.606 122.852 1.00 58.50 ? 393 TYR D CZ  1 
ATOM   12746 O OH  . TYR D 1 393 ? 132.188 134.606 123.682 1.00 58.50 ? 393 TYR D OH  1 
ATOM   12747 N N   . PRO D 1 394 ? 133.372 139.734 116.776 1.00 66.62 ? 394 PRO D N   1 
ATOM   12748 C CA  . PRO D 1 394 ? 133.745 140.825 115.873 1.00 66.62 ? 394 PRO D CA  1 
ATOM   12749 C C   . PRO D 1 394 ? 133.375 142.191 116.424 1.00 66.62 ? 394 PRO D C   1 
ATOM   12750 O O   . PRO D 1 394 ? 134.019 143.190 116.093 1.00 66.62 ? 394 PRO D O   1 
ATOM   12751 C CB  . PRO D 1 394 ? 132.955 140.503 114.602 1.00 66.62 ? 394 PRO D CB  1 
ATOM   12752 C CG  . PRO D 1 394 ? 131.770 139.746 115.085 1.00 66.62 ? 394 PRO D CG  1 
ATOM   12753 C CD  . PRO D 1 394 ? 132.223 138.961 116.274 1.00 66.62 ? 394 PRO D CD  1 
ATOM   12754 N N   . MET D 1 395 ? 132.345 142.233 117.276 1.00 66.91 ? 395 MET D N   1 
ATOM   12755 C CA  . MET D 1 395 ? 131.757 143.499 117.704 1.00 66.91 ? 395 MET D CA  1 
ATOM   12756 C C   . MET D 1 395 ? 132.785 144.433 118.326 1.00 66.91 ? 395 MET D C   1 
ATOM   12757 O O   . MET D 1 395 ? 132.731 145.648 118.120 1.00 66.91 ? 395 MET D O   1 
ATOM   12758 C CB  . MET D 1 395 ? 130.621 143.232 118.688 1.00 66.91 ? 395 MET D CB  1 
ATOM   12759 C CG  . MET D 1 395 ? 130.971 142.230 119.769 1.00 66.91 ? 395 MET D CG  1 
ATOM   12760 S SD  . MET D 1 395 ? 129.548 141.270 120.301 1.00 66.91 ? 395 MET D SD  1 
ATOM   12761 C CE  . MET D 1 395 ? 129.266 140.269 118.853 1.00 66.91 ? 395 MET D CE  1 
ATOM   12762 N N   . CYS D 1 396 ? 133.741 143.885 119.078 1.00 72.46 ? 396 CYS D N   1 
ATOM   12763 C CA  . CYS D 1 396 ? 134.717 144.722 119.768 1.00 72.46 ? 396 CYS D CA  1 
ATOM   12764 C C   . CYS D 1 396 ? 135.521 145.587 118.808 1.00 72.46 ? 396 CYS D C   1 
ATOM   12765 O O   . CYS D 1 396 ? 136.129 146.573 119.237 1.00 72.46 ? 396 CYS D O   1 
ATOM   12766 C CB  . CYS D 1 396 ? 135.660 143.854 120.602 1.00 72.46 ? 396 CYS D CB  1 
ATOM   12767 S SG  . CYS D 1 396 ? 136.584 142.629 119.650 1.00 72.46 ? 396 CYS D SG  1 
ATOM   12768 N N   . ASP D 1 397 ? 135.542 145.238 117.525 1.00 75.52 ? 397 ASP D N   1 
ATOM   12769 C CA  . ASP D 1 397 ? 136.172 146.049 116.497 1.00 75.52 ? 397 ASP D CA  1 
ATOM   12770 C C   . ASP D 1 397 ? 135.161 146.781 115.636 1.00 75.52 ? 397 ASP D C   1 
ATOM   12771 O O   . ASP D 1 397 ? 135.384 147.940 115.281 1.00 75.52 ? 397 ASP D O   1 
ATOM   12772 C CB  . ASP D 1 397 ? 137.059 145.179 115.607 1.00 75.52 ? 397 ASP D CB  1 
ATOM   12773 C CG  . ASP D 1 397 ? 138.185 144.534 116.374 1.00 75.52 ? 397 ASP D CG  1 
ATOM   12774 O OD1 . ASP D 1 397 ? 138.278 144.776 117.592 1.00 75.52 ? 397 ASP D OD1 1 
ATOM   12775 O OD2 . ASP D 1 397 ? 138.976 143.784 115.767 1.00 75.52 ? 397 ASP D OD2 1 
ATOM   12776 N N   . ALA D 1 398 ? 134.047 146.130 115.299 1.00 75.10 ? 398 ALA D N   1 
ATOM   12777 C CA  . ALA D 1 398 ? 133.025 146.786 114.493 1.00 75.10 ? 398 ALA D CA  1 
ATOM   12778 C C   . ALA D 1 398 ? 132.411 147.973 115.219 1.00 75.10 ? 398 ALA D C   1 
ATOM   12779 O O   . ALA D 1 398 ? 131.868 148.879 114.578 1.00 75.10 ? 398 ALA D O   1 
ATOM   12780 C CB  . ALA D 1 398 ? 131.937 145.786 114.106 1.00 75.10 ? 398 ALA D CB  1 
ATOM   12781 N N   . ASN D 1 399 ? 132.481 147.987 116.545 1.00 76.97 ? 399 ASN D N   1 
ATOM   12782 C CA  . ASN D 1 399 ? 131.914 149.056 117.353 1.00 76.97 ? 399 ASN D CA  1 
ATOM   12783 C C   . ASN D 1 399 ? 132.989 149.585 118.290 1.00 76.97 ? 399 ASN D C   1 
ATOM   12784 O O   . ASN D 1 399 ? 133.498 148.823 119.129 1.00 76.97 ? 399 ASN D O   1 
ATOM   12785 C CB  . ASN D 1 399 ? 130.712 148.544 118.146 1.00 76.97 ? 399 ASN D CB  1 
ATOM   12786 C CG  . ASN D 1 399 ? 129.874 149.657 118.722 1.00 76.97 ? 399 ASN D CG  1 
ATOM   12787 O OD1 . ASN D 1 399 ? 130.370 150.747 118.999 1.00 76.97 ? 399 ASN D OD1 1 
ATOM   12788 N ND2 . ASN D 1 399 ? 128.590 149.386 118.913 1.00 76.97 ? 399 ASN D ND2 1 
ATOM   12789 N N   . PRO D 1 400 ? 133.381 150.856 118.189 1.00 77.55 ? 400 PRO D N   1 
ATOM   12790 C CA  . PRO D 1 400 ? 134.339 151.393 119.168 1.00 77.55 ? 400 PRO D CA  1 
ATOM   12791 C C   . PRO D 1 400 ? 133.793 151.392 120.581 1.00 77.55 ? 400 PRO D C   1 
ATOM   12792 O O   . PRO D 1 400 ? 134.523 151.072 121.526 1.00 77.55 ? 400 PRO D O   1 
ATOM   12793 C CB  . PRO D 1 400 ? 134.598 152.817 118.660 1.00 77.55 ? 400 PRO D CB  1 
ATOM   12794 C CG  . PRO D 1 400 ? 134.176 152.798 117.229 1.00 77.55 ? 400 PRO D CG  1 
ATOM   12795 C CD  . PRO D 1 400 ? 133.040 151.838 117.151 1.00 77.55 ? 400 PRO D CD  1 
ATOM   12796 N N   . GLN D 1 401 ? 132.523 151.743 120.748 1.00 78.10 ? 401 GLN D N   1 
ATOM   12797 C CA  . GLN D 1 401 ? 131.860 151.704 122.047 1.00 78.10 ? 401 GLN D CA  1 
ATOM   12798 C C   . GLN D 1 401 ? 131.184 150.351 122.186 1.00 78.10 ? 401 GLN D C   1 
ATOM   12799 O O   . GLN D 1 401 ? 130.067 150.152 121.705 1.00 78.10 ? 401 GLN D O   1 
ATOM   12800 C CB  . GLN D 1 401 ? 130.847 152.832 122.175 1.00 78.10 ? 401 GLN D CB  1 
ATOM   12801 C CG  . GLN D 1 401 ? 131.427 154.221 122.026 1.00 78.10 ? 401 GLN D CG  1 
ATOM   12802 C CD  . GLN D 1 401 ? 130.357 155.285 122.059 1.00 78.10 ? 401 GLN D CD  1 
ATOM   12803 O OE1 . GLN D 1 401 ? 130.630 156.465 121.850 1.00 78.10 ? 401 GLN D OE1 1 
ATOM   12804 N NE2 . GLN D 1 401 ? 129.125 154.871 122.324 1.00 78.10 ? 401 GLN D NE2 1 
ATOM   12805 N N   . SER D 1 402 ? 131.852 149.422 122.861 1.00 75.07 ? 402 SER D N   1 
ATOM   12806 C CA  . SER D 1 402 ? 131.368 148.058 122.993 1.00 75.07 ? 402 SER D CA  1 
ATOM   12807 C C   . SER D 1 402 ? 131.537 147.597 124.429 1.00 75.07 ? 402 SER D C   1 
ATOM   12808 O O   . SER D 1 402 ? 132.552 147.890 125.065 1.00 75.07 ? 402 SER D O   1 
ATOM   12809 C CB  . SER D 1 402 ? 132.117 147.128 122.043 1.00 75.07 ? 402 SER D CB  1 
ATOM   12810 O OG  . SER D 1 402 ? 133.499 147.142 122.333 1.00 75.07 ? 402 SER D OG  1 
ATOM   12811 N N   . THR D 1 403 ? 130.535 146.874 124.935 1.00 69.87 ? 403 THR D N   1 
ATOM   12812 C CA  . THR D 1 403 ? 130.497 146.493 126.341 1.00 69.87 ? 403 THR D CA  1 
ATOM   12813 C C   . THR D 1 403 ? 130.169 145.021 126.550 1.00 69.87 ? 403 THR D C   1 
ATOM   12814 O O   . THR D 1 403 ? 130.029 144.592 127.700 1.00 69.87 ? 403 THR D O   1 
ATOM   12815 C CB  . THR D 1 403 ? 129.470 147.339 127.101 1.00 69.87 ? 403 THR D CB  1 
ATOM   12816 O OG1 . THR D 1 403 ? 128.158 147.038 126.615 1.00 69.87 ? 403 THR D OG1 1 
ATOM   12817 C CG2 . THR D 1 403 ? 129.745 148.812 126.918 1.00 69.87 ? 403 THR D CG2 1 
ATOM   12818 N N   . HIS D 1 404 ? 130.059 144.233 125.483 1.00 61.66 ? 404 HIS D N   1 
ATOM   12819 C CA  . HIS D 1 404 ? 129.294 142.998 125.525 1.00 61.66 ? 404 HIS D CA  1 
ATOM   12820 C C   . HIS D 1 404 ? 130.105 141.722 125.381 1.00 61.66 ? 404 HIS D C   1 
ATOM   12821 O O   . HIS D 1 404 ? 129.524 140.636 125.440 1.00 61.66 ? 404 HIS D O   1 
ATOM   12822 C CB  . HIS D 1 404 ? 128.217 143.035 124.441 1.00 61.66 ? 404 HIS D CB  1 
ATOM   12823 C CG  . HIS D 1 404 ? 127.046 143.883 124.806 1.00 61.66 ? 404 HIS D CG  1 
ATOM   12824 N ND1 . HIS D 1 404 ? 126.862 144.374 126.078 1.00 61.66 ? 404 HIS D ND1 1 
ATOM   12825 C CD2 . HIS D 1 404 ? 126.001 144.328 124.073 1.00 61.66 ? 404 HIS D CD2 1 
ATOM   12826 C CE1 . HIS D 1 404 ? 125.751 145.086 126.114 1.00 61.66 ? 404 HIS D CE1 1 
ATOM   12827 N NE2 . HIS D 1 404 ? 125.209 145.073 124.911 1.00 61.66 ? 404 HIS D NE2 1 
ATOM   12828 N N   . ALA D 1 405 ? 131.418 141.801 125.207 1.00 59.72 ? 405 ALA D N   1 
ATOM   12829 C CA  . ALA D 1 405 ? 132.191 140.570 125.125 1.00 59.72 ? 405 ALA D CA  1 
ATOM   12830 C C   . ALA D 1 405 ? 132.362 139.943 126.498 1.00 59.72 ? 405 ALA D C   1 
ATOM   12831 O O   . ALA D 1 405 ? 131.884 138.836 126.749 1.00 59.72 ? 405 ALA D O   1 
ATOM   12832 C CB  . ALA D 1 405 ? 133.553 140.835 124.488 1.00 59.72 ? 405 ALA D CB  1 
ATOM   12833 N N   . TYR D 1 406 ? 133.018 140.651 127.404 1.00 63.94 ? 406 TYR D N   1 
ATOM   12834 C CA  . TYR D 1 406 ? 133.431 140.102 128.684 1.00 63.94 ? 406 TYR D CA  1 
ATOM   12835 C C   . TYR D 1 406 ? 132.392 140.369 129.759 1.00 63.94 ? 406 TYR D C   1 
ATOM   12836 O O   . TYR D 1 406 ? 131.663 141.361 129.701 1.00 63.94 ? 406 TYR D O   1 
ATOM   12837 C CB  . TYR D 1 406 ? 134.767 140.697 129.105 1.00 63.94 ? 406 TYR D CB  1 
ATOM   12838 C CG  . TYR D 1 406 ? 135.767 140.679 127.994 1.00 63.94 ? 406 TYR D CG  1 
ATOM   12839 C CD1 . TYR D 1 406 ? 136.540 139.559 127.757 1.00 63.94 ? 406 TYR D CD1 1 
ATOM   12840 C CD2 . TYR D 1 406 ? 135.925 141.772 127.163 1.00 63.94 ? 406 TYR D CD2 1 
ATOM   12841 C CE1 . TYR D 1 406 ? 137.456 139.532 126.735 1.00 63.94 ? 406 TYR D CE1 1 
ATOM   12842 C CE2 . TYR D 1 406 ? 136.835 141.751 126.136 1.00 63.94 ? 406 TYR D CE2 1 
ATOM   12843 C CZ  . TYR D 1 406 ? 137.600 140.627 125.927 1.00 63.94 ? 406 TYR D CZ  1 
ATOM   12844 O OH  . TYR D 1 406 ? 138.515 140.588 124.906 1.00 63.94 ? 406 TYR D OH  1 
ATOM   12845 N N   . VAL D 1 407 ? 132.317 139.462 130.733 1.00 59.28 ? 407 VAL D N   1 
ATOM   12846 C CA  . VAL D 1 407 ? 131.465 139.624 131.898 1.00 59.28 ? 407 VAL D CA  1 
ATOM   12847 C C   . VAL D 1 407 ? 132.254 139.570 133.200 1.00 59.28 ? 407 VAL D C   1 
ATOM   12848 O O   . VAL D 1 407 ? 131.990 140.351 134.113 1.00 59.28 ? 407 VAL D O   1 
ATOM   12849 C CB  . VAL D 1 407 ? 130.310 138.602 131.906 1.00 59.28 ? 407 VAL D CB  1 
ATOM   12850 C CG1 . VAL D 1 407 ? 129.498 138.729 130.639 1.00 59.28 ? 407 VAL D CG1 1 
ATOM   12851 C CG2 . VAL D 1 407 ? 130.837 137.213 132.006 1.00 59.28 ? 407 VAL D CG2 1 
ATOM   12852 N N   . TRP D 1 408 ? 133.227 138.669 133.314 1.00 56.03 ? 408 TRP D N   1 
ATOM   12853 C CA  . TRP D 1 408 ? 133.974 138.515 134.552 1.00 56.03 ? 408 TRP D CA  1 
ATOM   12854 C C   . TRP D 1 408 ? 135.449 138.316 134.262 1.00 56.03 ? 408 TRP D C   1 
ATOM   12855 O O   . TRP D 1 408 ? 135.817 137.607 133.324 1.00 56.03 ? 408 TRP D O   1 
ATOM   12856 C CB  . TRP D 1 408 ? 133.453 137.332 135.378 1.00 56.03 ? 408 TRP D CB  1 
ATOM   12857 C CG  . TRP D 1 408 ? 132.059 137.508 135.785 1.00 56.03 ? 408 TRP D CG  1 
ATOM   12858 C CD1 . TRP D 1 408 ? 131.550 138.566 136.437 1.00 56.03 ? 408 TRP D CD1 1 
ATOM   12859 C CD2 . TRP D 1 408 ? 130.971 136.615 135.554 1.00 56.03 ? 408 TRP D CD2 1 
ATOM   12860 N NE1 . TRP D 1 408 ? 130.209 138.404 136.636 1.00 56.03 ? 408 TRP D NE1 1 
ATOM   12861 C CE2 . TRP D 1 408 ? 129.828 137.207 136.099 1.00 56.03 ? 408 TRP D CE2 1 
ATOM   12862 C CE3 . TRP D 1 408 ? 130.853 135.370 134.948 1.00 56.03 ? 408 TRP D CE3 1 
ATOM   12863 C CZ2 . TRP D 1 408 ? 128.581 136.605 136.054 1.00 56.03 ? 408 TRP D CZ2 1 
ATOM   12864 C CZ3 . TRP D 1 408 ? 129.612 134.776 134.899 1.00 56.03 ? 408 TRP D CZ3 1 
ATOM   12865 C CH2 . TRP D 1 408 ? 128.495 135.390 135.450 1.00 56.03 ? 408 TRP D CH2 1 
ATOM   12866 N N   . ILE D 1 409 ? 136.288 138.938 135.081 1.00 62.27 ? 409 ILE D N   1 
ATOM   12867 C CA  . ILE D 1 409 ? 137.726 138.702 135.063 1.00 62.27 ? 409 ILE D CA  1 
ATOM   12868 C C   . ILE D 1 409 ? 138.084 138.097 136.409 1.00 62.27 ? 409 ILE D C   1 
ATOM   12869 O O   . ILE D 1 409 ? 138.040 138.790 137.436 1.00 62.27 ? 409 ILE D O   1 
ATOM   12870 C CB  . ILE D 1 409 ? 138.526 139.984 134.813 1.00 62.27 ? 409 ILE D CB  1 
ATOM   12871 C CG1 . ILE D 1 409 ? 137.804 140.885 133.816 1.00 62.27 ? 409 ILE D CG1 1 
ATOM   12872 C CG2 . ILE D 1 409 ? 139.902 139.645 134.300 1.00 62.27 ? 409 ILE D CG2 1 
ATOM   12873 C CD1 . ILE D 1 409 ? 137.706 140.296 132.440 1.00 62.27 ? 409 ILE D CD1 1 
ATOM   12874 N N   . SER D 1 410 ? 138.424 136.813 136.425 1.00 64.70 ? 410 SER D N   1 
ATOM   12875 C CA  . SER D 1 410 ? 138.624 136.114 137.682 1.00 64.70 ? 410 SER D CA  1 
ATOM   12876 C C   . SER D 1 410 ? 140.093 135.800 137.901 1.00 64.70 ? 410 SER D C   1 
ATOM   12877 O O   . SER D 1 410 ? 140.807 135.412 136.969 1.00 64.70 ? 410 SER D O   1 
ATOM   12878 C CB  . SER D 1 410 ? 137.803 134.834 137.727 1.00 64.70 ? 410 SER D CB  1 
ATOM   12879 O OG  . SER D 1 410 ? 137.992 134.162 138.950 1.00 64.70 ? 410 SER D OG  1 
ATOM   12880 N N   . LEU D 1 411 ? 140.522 135.956 139.147 1.00 67.52 ? 411 LEU D N   1 
ATOM   12881 C CA  . LEU D 1 411 ? 141.894 135.757 139.571 1.00 67.52 ? 411 LEU D CA  1 
ATOM   12882 C C   . LEU D 1 411 ? 141.945 134.748 140.708 1.00 67.52 ? 411 LEU D C   1 
ATOM   12883 O O   . LEU D 1 411 ? 141.005 134.629 141.495 1.00 67.52 ? 411 LEU D O   1 
ATOM   12884 C CB  . LEU D 1 411 ? 142.518 137.068 140.043 1.00 67.52 ? 411 LEU D CB  1 
ATOM   12885 C CG  . LEU D 1 411 ? 142.556 138.227 139.055 1.00 67.52 ? 411 LEU D CG  1 
ATOM   12886 C CD1 . LEU D 1 411 ? 141.263 139.016 139.083 1.00 67.52 ? 411 LEU D CD1 1 
ATOM   12887 C CD2 . LEU D 1 411 ? 143.721 139.112 139.391 1.00 67.52 ? 411 LEU D CD2 1 
ATOM   12888 N N   . ALA D 1 412 ? 143.047 134.012 140.771 1.00 70.62 ? 412 ALA D N   1 
ATOM   12889 C CA  . ALA D 1 412 ? 143.384 133.177 141.912 1.00 70.62 ? 412 ALA D CA  1 
ATOM   12890 C C   . ALA D 1 412 ? 144.803 132.692 141.717 1.00 70.62 ? 412 ALA D C   1 
ATOM   12891 O O   . ALA D 1 412 ? 145.153 132.244 140.628 1.00 70.62 ? 412 ALA D O   1 
ATOM   12892 C CB  . ALA D 1 412 ? 142.439 131.981 142.052 1.00 70.62 ? 412 ALA D CB  1 
ATOM   12893 N N   . TYR D 1 413 ? 145.612 132.779 142.762 1.00 80.77 ? 413 TYR D N   1 
ATOM   12894 C CA  . TYR D 1 413 ? 146.993 132.330 142.700 1.00 80.77 ? 413 TYR D CA  1 
ATOM   12895 C C   . TYR D 1 413 ? 147.112 131.027 143.470 1.00 80.77 ? 413 TYR D C   1 
ATOM   12896 O O   . TYR D 1 413 ? 146.907 131.002 144.687 1.00 80.77 ? 413 TYR D O   1 
ATOM   12897 C CB  . TYR D 1 413 ? 147.950 133.376 143.263 1.00 80.77 ? 413 TYR D CB  1 
ATOM   12898 C CG  . TYR D 1 413 ? 149.330 133.308 142.653 1.00 80.77 ? 413 TYR D CG  1 
ATOM   12899 C CD1 . TYR D 1 413 ? 150.178 132.252 142.931 1.00 80.77 ? 413 TYR D CD1 1 
ATOM   12900 C CD2 . TYR D 1 413 ? 149.783 134.301 141.799 1.00 80.77 ? 413 TYR D CD2 1 
ATOM   12901 C CE1 . TYR D 1 413 ? 151.438 132.184 142.374 1.00 80.77 ? 413 TYR D CE1 1 
ATOM   12902 C CE2 . TYR D 1 413 ? 151.043 134.244 141.240 1.00 80.77 ? 413 TYR D CE2 1 
ATOM   12903 C CZ  . TYR D 1 413 ? 151.864 133.183 141.531 1.00 80.77 ? 413 TYR D CZ  1 
ATOM   12904 O OH  . TYR D 1 413 ? 153.117 133.121 140.979 1.00 80.77 ? 413 TYR D OH  1 
ATOM   12905 N N   . LYS D 1 414 ? 147.438 129.956 142.765 1.00 79.78 ? 414 LYS D N   1 
ATOM   12906 C CA  . LYS D 1 414 ? 147.618 128.647 143.362 1.00 79.78 ? 414 LYS D CA  1 
ATOM   12907 C C   . LYS D 1 414 ? 149.105 128.384 143.530 1.00 79.78 ? 414 LYS D C   1 
ATOM   12908 O O   . LYS D 1 414 ? 149.931 129.281 143.366 1.00 79.78 ? 414 LYS D O   1 
ATOM   12909 C CB  . LYS D 1 414 ? 146.915 127.576 142.528 1.00 79.78 ? 414 LYS D CB  1 
ATOM   12910 C CG  . LYS D 1 414 ? 145.415 127.584 142.762 1.00 79.78 ? 414 LYS D CG  1 
ATOM   12911 C CD  . LYS D 1 414 ? 144.650 126.699 141.809 1.00 79.78 ? 414 LYS D CD  1 
ATOM   12912 C CE  . LYS D 1 414 ? 143.161 126.767 142.120 1.00 79.78 ? 414 LYS D CE  1 
ATOM   12913 N NZ  . LYS D 1 414 ? 142.319 126.125 141.079 1.00 79.78 ? 414 LYS D NZ  1 
ATOM   12914 N N   . LYS D 1 415 ? 149.441 127.142 143.879 1.00 88.85 ? 415 LYS D N   1 
ATOM   12915 C CA  . LYS D 1 415 ? 150.776 126.855 144.395 1.00 88.85 ? 415 LYS D CA  1 
ATOM   12916 C C   . LYS D 1 415 ? 151.864 127.199 143.383 1.00 88.85 ? 415 LYS D C   1 
ATOM   12917 O O   . LYS D 1 415 ? 153.016 127.444 143.761 1.00 88.85 ? 415 LYS D O   1 
ATOM   12918 C CB  . LYS D 1 415 ? 150.870 125.388 144.815 1.00 88.85 ? 415 LYS D CB  1 
ATOM   12919 C CG  . LYS D 1 415 ? 152.128 125.033 145.603 1.00 88.85 ? 415 LYS D CG  1 
ATOM   12920 C CD  . LYS D 1 415 ? 153.234 124.485 144.720 1.00 88.85 ? 415 LYS D CD  1 
ATOM   12921 C CE  . LYS D 1 415 ? 152.897 123.104 144.195 1.00 88.85 ? 415 LYS D CE  1 
ATOM   12922 N NZ  . LYS D 1 415 ? 153.998 122.562 143.349 1.00 88.85 ? 415 LYS D NZ  1 
ATOM   12923 N N   . THR D 1 416 ? 151.524 127.243 142.097 1.00 84.70 ? 416 THR D N   1 
ATOM   12924 C CA  . THR D 1 416 ? 152.494 127.599 141.070 1.00 84.70 ? 416 THR D CA  1 
ATOM   12925 C C   . THR D 1 416 ? 152.175 128.911 140.374 1.00 84.70 ? 416 THR D C   1 
ATOM   12926 O O   . THR D 1 416 ? 153.009 129.818 140.357 1.00 84.70 ? 416 THR D O   1 
ATOM   12927 C CB  . THR D 1 416 ? 152.600 126.484 140.028 1.00 84.70 ? 416 THR D CB  1 
ATOM   12928 O OG1 . THR D 1 416 ? 153.061 125.289 140.663 1.00 84.70 ? 416 THR D OG1 1 
ATOM   12929 C CG2 . THR D 1 416 ? 153.578 126.885 138.939 1.00 84.70 ? 416 THR D CG2 1 
ATOM   12930 N N   . GLY D 1 417 ? 150.985 129.045 139.796 1.00 79.35 ? 417 GLY D N   1 
ATOM   12931 C CA  . GLY D 1 417 ? 150.657 130.221 139.025 1.00 79.35 ? 417 GLY D CA  1 
ATOM   12932 C C   . GLY D 1 417 ? 149.256 130.739 139.266 1.00 79.35 ? 417 GLY D C   1 
ATOM   12933 O O   . GLY D 1 417 ? 148.454 130.133 139.982 1.00 79.35 ? 417 GLY D O   1 
ATOM   12934 N N   . PRO D 1 418 ? 148.943 131.886 138.671 1.00 73.72 ? 418 PRO D N   1 
ATOM   12935 C CA  . PRO D 1 418 ? 147.600 132.450 138.807 1.00 73.72 ? 418 PRO D CA  1 
ATOM   12936 C C   . PRO D 1 418 ? 146.577 131.642 138.032 1.00 73.72 ? 418 PRO D C   1 
ATOM   12937 O O   . PRO D 1 418 ? 146.889 130.853 137.140 1.00 73.72 ? 418 PRO D O   1 
ATOM   12938 C CB  . PRO D 1 418 ? 147.737 133.858 138.227 1.00 73.72 ? 418 PRO D CB  1 
ATOM   12939 C CG  . PRO D 1 418 ? 149.190 134.127 138.193 1.00 73.72 ? 418 PRO D CG  1 
ATOM   12940 C CD  . PRO D 1 418 ? 149.852 132.808 137.979 1.00 73.72 ? 418 PRO D CD  1 
ATOM   12941 N N   . TYR D 1 419 ? 145.324 131.871 138.381 1.00 67.22 ? 419 TYR D N   1 
ATOM   12942 C CA  . TYR D 1 419 ? 144.195 131.212 137.740 1.00 67.22 ? 419 TYR D CA  1 
ATOM   12943 C C   . TYR D 1 419 ? 143.303 132.333 137.239 1.00 67.22 ? 419 TYR D C   1 
ATOM   12944 O O   . TYR D 1 419 ? 142.285 132.657 137.849 1.00 67.22 ? 419 TYR D O   1 
ATOM   12945 C CB  . TYR D 1 419 ? 143.494 130.314 138.732 1.00 67.22 ? 419 TYR D CB  1 
ATOM   12946 C CG  . TYR D 1 419 ? 142.508 129.338 138.165 1.00 67.22 ? 419 TYR D CG  1 
ATOM   12947 C CD1 . TYR D 1 419 ? 141.194 129.711 137.920 1.00 67.22 ? 419 TYR D CD1 1 
ATOM   12948 C CD2 . TYR D 1 419 ? 142.877 128.027 137.913 1.00 67.22 ? 419 TYR D CD2 1 
ATOM   12949 C CE1 . TYR D 1 419 ? 140.280 128.804 137.418 1.00 67.22 ? 419 TYR D CE1 1 
ATOM   12950 C CE2 . TYR D 1 419 ? 141.976 127.120 137.415 1.00 67.22 ? 419 TYR D CE2 1 
ATOM   12951 C CZ  . TYR D 1 419 ? 140.681 127.511 137.167 1.00 67.22 ? 419 TYR D CZ  1 
ATOM   12952 O OH  . TYR D 1 419 ? 139.791 126.595 136.663 1.00 67.22 ? 419 TYR D OH  1 
ATOM   12953 N N   . ILE D 1 420 ? 143.675 132.899 136.099 1.00 63.20 ? 420 ILE D N   1 
ATOM   12954 C CA  . ILE D 1 420 ? 142.956 134.015 135.505 1.00 63.20 ? 420 ILE D CA  1 
ATOM   12955 C C   . ILE D 1 420 ? 142.044 133.447 134.442 1.00 63.20 ? 420 ILE D C   1 
ATOM   12956 O O   . ILE D 1 420 ? 142.509 132.858 133.460 1.00 63.20 ? 420 ILE D O   1 
ATOM   12957 C CB  . ILE D 1 420 ? 143.909 135.055 134.903 1.00 63.20 ? 420 ILE D CB  1 
ATOM   12958 C CG1 . ILE D 1 420 ? 144.910 135.527 135.950 1.00 63.20 ? 420 ILE D CG1 1 
ATOM   12959 C CG2 . ILE D 1 420 ? 143.122 136.220 134.362 1.00 63.20 ? 420 ILE D CG2 1 
ATOM   12960 C CD1 . ILE D 1 420 ? 145.711 136.717 135.520 1.00 63.20 ? 420 ILE D CD1 1 
ATOM   12961 N N   . THR D 1 421 ? 140.752 133.608 134.638 1.00 57.26 ? 421 THR D N   1 
ATOM   12962 C CA  . THR D 1 421 ? 139.771 133.108 133.698 1.00 57.26 ? 421 THR D CA  1 
ATOM   12963 C C   . THR D 1 421 ? 138.910 134.256 133.209 1.00 57.26 ? 421 THR D C   1 
ATOM   12964 O O   . THR D 1 421 ? 138.395 135.051 134.006 1.00 57.26 ? 421 THR D O   1 
ATOM   12965 C CB  . THR D 1 421 ? 138.956 131.975 134.318 1.00 57.26 ? 421 THR D CB  1 
ATOM   12966 O OG1 . THR D 1 421 ? 137.726 131.788 133.608 1.00 57.26 ? 421 THR D OG1 1 
ATOM   12967 C CG2 . THR D 1 421 ? 138.753 132.178 135.787 1.00 57.26 ? 421 THR D CG2 1 
ATOM   12968 N N   . VAL D 1 422 ? 138.811 134.353 131.891 1.00 53.46 ? 422 VAL D N   1 
ATOM   12969 C CA  . VAL D 1 422 ? 138.198 135.482 131.211 1.00 53.46 ? 422 VAL D CA  1 
ATOM   12970 C C   . VAL D 1 422 ? 136.839 134.977 130.760 1.00 53.46 ? 422 VAL D C   1 
ATOM   12971 O O   . VAL D 1 422 ? 136.700 134.340 129.724 1.00 53.46 ? 422 VAL D O   1 
ATOM   12972 C CB  . VAL D 1 422 ? 139.054 135.973 130.047 1.00 53.46 ? 422 VAL D CB  1 
ATOM   12973 C CG1 . VAL D 1 422 ? 138.310 136.988 129.238 1.00 53.46 ? 422 VAL D CG1 1 
ATOM   12974 C CG2 . VAL D 1 422 ? 140.342 136.564 130.560 1.00 53.46 ? 422 VAL D CG2 1 
ATOM   12975 N N   . TYR D 1 423 ? 135.828 135.230 131.571 1.00 53.69 ? 423 TYR D N   1 
ATOM   12976 C CA  . TYR D 1 423 ? 134.503 134.759 131.230 1.00 53.69 ? 423 TYR D CA  1 
ATOM   12977 C C   . TYR D 1 423 ? 133.907 135.675 130.185 1.00 53.69 ? 423 TYR D C   1 
ATOM   12978 O O   . TYR D 1 423 ? 134.029 136.896 130.264 1.00 53.69 ? 423 TYR D O   1 
ATOM   12979 C CB  . TYR D 1 423 ? 133.628 134.710 132.473 1.00 53.69 ? 423 TYR D CB  1 
ATOM   12980 C CG  . TYR D 1 423 ? 134.214 133.839 133.549 1.00 53.69 ? 423 TYR D CG  1 
ATOM   12981 C CD1 . TYR D 1 423 ? 135.216 134.298 134.376 1.00 53.69 ? 423 TYR D CD1 1 
ATOM   12982 C CD2 . TYR D 1 423 ? 133.790 132.546 133.710 1.00 53.69 ? 423 TYR D CD2 1 
ATOM   12983 C CE1 . TYR D 1 423 ? 135.749 133.500 135.340 1.00 53.69 ? 423 TYR D CE1 1 
ATOM   12984 C CE2 . TYR D 1 423 ? 134.316 131.740 134.670 1.00 53.69 ? 423 TYR D CE2 1 
ATOM   12985 C CZ  . TYR D 1 423 ? 135.300 132.217 135.482 1.00 53.69 ? 423 TYR D CZ  1 
ATOM   12986 O OH  . TYR D 1 423 ? 135.826 131.397 136.447 1.00 53.69 ? 423 TYR D OH  1 
ATOM   12987 N N   . THR D 1 424 ? 133.285 135.080 129.185 1.00 50.42 ? 424 THR D N   1 
ATOM   12988 C CA  . THR D 1 424 ? 132.686 135.832 128.107 1.00 50.42 ? 424 THR D CA  1 
ATOM   12989 C C   . THR D 1 424 ? 131.210 135.522 128.057 1.00 50.42 ? 424 THR D C   1 
ATOM   12990 O O   . THR D 1 424 ? 130.713 134.629 128.738 1.00 50.42 ? 424 THR D O   1 
ATOM   12991 C CB  . THR D 1 424 ? 133.322 135.500 126.758 1.00 50.42 ? 424 THR D CB  1 
ATOM   12992 O OG1 . THR D 1 424 ? 133.228 134.092 126.527 1.00 50.42 ? 424 THR D OG1 1 
ATOM   12993 C CG2 . THR D 1 424 ? 134.772 135.927 126.725 1.00 50.42 ? 424 THR D CG2 1 
ATOM   12994 N N   . ASN D 1 425 ? 130.511 136.287 127.249 1.00 48.61 ? 425 ASN D N   1 
ATOM   12995 C CA  . ASN D 1 425 ? 129.154 135.931 126.884 1.00 48.61 ? 425 ASN D CA  1 
ATOM   12996 C C   . ASN D 1 425 ? 129.234 135.400 125.471 1.00 48.61 ? 425 ASN D C   1 
ATOM   12997 O O   . ASN D 1 425 ? 129.351 136.186 124.521 1.00 48.61 ? 425 ASN D O   1 
ATOM   12998 C CB  . ASN D 1 425 ? 128.221 137.135 126.962 1.00 48.61 ? 425 ASN D CB  1 
ATOM   12999 C CG  . ASN D 1 425 ? 126.776 136.742 126.930 1.00 48.61 ? 425 ASN D CG  1 
ATOM   13000 O OD1 . ASN D 1 425 ? 126.447 135.563 126.958 1.00 48.61 ? 425 ASN D OD1 1 
ATOM   13001 N ND2 . ASN D 1 425 ? 125.897 137.728 126.878 1.00 48.61 ? 425 ASN D ND2 1 
ATOM   13002 N N   . PRO D 1 426 ? 129.226 134.087 125.270 1.00 48.29 ? 426 PRO D N   1 
ATOM   13003 C CA  . PRO D 1 426 ? 129.200 133.559 123.907 1.00 48.29 ? 426 PRO D CA  1 
ATOM   13004 C C   . PRO D 1 426 ? 127.950 133.939 123.147 1.00 48.29 ? 426 PRO D C   1 
ATOM   13005 O O   . PRO D 1 426 ? 127.872 133.660 121.949 1.00 48.29 ? 426 PRO D O   1 
ATOM   13006 C CB  . PRO D 1 426 ? 129.291 132.048 124.120 1.00 48.29 ? 426 PRO D CB  1 
ATOM   13007 C CG  . PRO D 1 426 ? 128.762 131.837 125.479 1.00 48.29 ? 426 PRO D CG  1 
ATOM   13008 C CD  . PRO D 1 426 ? 129.196 133.015 126.270 1.00 48.29 ? 426 PRO D CD  1 
ATOM   13009 N N   . GLY D 1 427 ? 126.976 134.561 123.795 1.00 48.78 ? 427 GLY D N   1 
ATOM   13010 C CA  . GLY D 1 427 ? 125.786 135.020 123.118 1.00 48.78 ? 427 GLY D CA  1 
ATOM   13011 C C   . GLY D 1 427 ? 125.759 136.524 122.966 1.00 48.78 ? 427 GLY D C   1 
ATOM   13012 O O   . GLY D 1 427 ? 124.691 137.120 122.816 1.00 48.78 ? 427 GLY D O   1 
ATOM   13013 N N   . ALA D 1 428 ? 126.935 137.149 123.014 1.00 51.15 ? 428 ALA D N   1 
ATOM   13014 C CA  . ALA D 1 428 ? 127.009 138.592 122.840 1.00 51.15 ? 428 ALA D CA  1 
ATOM   13015 C C   . ALA D 1 428 ? 126.421 139.018 121.511 1.00 51.15 ? 428 ALA D C   1 
ATOM   13016 O O   . ALA D 1 428 ? 125.794 140.076 121.419 1.00 51.15 ? 428 ALA D O   1 
ATOM   13017 C CB  . ALA D 1 428 ? 128.454 139.058 122.939 1.00 51.15 ? 428 ALA D CB  1 
ATOM   13018 N N   . SER D 1 429 ? 126.608 138.208 120.472 1.00 49.77 ? 429 SER D N   1 
ATOM   13019 C CA  . SER D 1 429 ? 126.044 138.531 119.171 1.00 49.77 ? 429 SER D CA  1 
ATOM   13020 C C   . SER D 1 429 ? 124.536 138.678 119.238 1.00 49.77 ? 429 SER D C   1 
ATOM   13021 O O   . SER D 1 429 ? 123.945 139.357 118.396 1.00 49.77 ? 429 SER D O   1 
ATOM   13022 C CB  . SER D 1 429 ? 126.438 137.464 118.156 1.00 49.77 ? 429 SER D CB  1 
ATOM   13023 O OG  . SER D 1 429 ? 125.906 136.212 118.519 1.00 49.77 ? 429 SER D OG  1 
ATOM   13024 N N   . ILE D 1 430 ? 123.892 138.053 120.224 1.00 49.16 ? 430 ILE D N   1 
ATOM   13025 C CA  . ILE D 1 430 ? 122.462 138.251 120.386 1.00 49.16 ? 430 ILE D CA  1 
ATOM   13026 C C   . ILE D 1 430 ? 122.172 139.650 120.900 1.00 49.16 ? 430 ILE D C   1 
ATOM   13027 O O   . ILE D 1 430 ? 121.082 140.184 120.672 1.00 49.16 ? 430 ILE D O   1 
ATOM   13028 C CB  . ILE D 1 430 ? 121.886 137.191 121.336 1.00 49.16 ? 430 ILE D CB  1 
ATOM   13029 C CG1 . ILE D 1 430 ? 122.309 135.802 120.881 1.00 49.16 ? 430 ILE D CG1 1 
ATOM   13030 C CG2 . ILE D 1 430 ? 120.379 137.251 121.342 1.00 49.16 ? 430 ILE D CG2 1 
ATOM   13031 C CD1 . ILE D 1 430 ? 122.102 134.736 121.914 1.00 49.16 ? 430 ILE D CD1 1 
ATOM   13032 N N   . LEU D 1 431 ? 123.136 140.269 121.577 1.00 52.21 ? 431 LEU D N   1 
ATOM   13033 C CA  . LEU D 1 431 ? 122.970 141.624 122.079 1.00 52.21 ? 431 LEU D CA  1 
ATOM   13034 C C   . LEU D 1 431 ? 123.365 142.674 121.054 1.00 52.21 ? 431 LEU D C   1 
ATOM   13035 O O   . LEU D 1 431 ? 123.700 143.799 121.435 1.00 52.21 ? 431 LEU D O   1 
ATOM   13036 C CB  . LEU D 1 431 ? 123.789 141.811 123.354 1.00 52.21 ? 431 LEU D CB  1 
ATOM   13037 C CG  . LEU D 1 431 ? 123.525 140.772 124.443 1.00 52.21 ? 431 LEU D CG  1 
ATOM   13038 C CD1 . LEU D 1 431 ? 124.240 141.139 125.716 1.00 52.21 ? 431 LEU D CD1 1 
ATOM   13039 C CD2 . LEU D 1 431 ? 122.042 140.634 124.695 1.00 52.21 ? 431 LEU D CD2 1 
ATOM   13040 N N   . GLU D 1 432 ? 123.359 142.325 119.775 1.00 55.14 ? 432 GLU D N   1 
ATOM   13041 C CA  . GLU D 1 432 ? 123.693 143.256 118.712 1.00 55.14 ? 432 GLU D CA  1 
ATOM   13042 C C   . GLU D 1 432 ? 122.678 143.162 117.583 1.00 55.14 ? 432 GLU D C   1 
ATOM   13043 O O   . GLU D 1 432 ? 121.484 143.004 117.825 1.00 55.14 ? 432 GLU D O   1 
ATOM   13044 C CB  . GLU D 1 432 ? 125.097 142.982 118.185 1.00 55.14 ? 432 GLU D CB  1 
ATOM   13045 C CG  . GLU D 1 432 ? 126.151 142.983 119.255 1.00 55.14 ? 432 GLU D CG  1 
ATOM   13046 C CD  . GLU D 1 432 ? 126.321 144.344 119.883 1.00 55.14 ? 432 GLU D CD  1 
ATOM   13047 O OE1 . GLU D 1 432 ? 125.963 145.347 119.236 1.00 55.14 ? 432 GLU D OE1 1 
ATOM   13048 O OE2 . GLU D 1 432 ? 126.808 144.418 121.028 1.00 55.14 ? 432 GLU D OE2 1 
HETATM 13049 O O4  . DST E 2 .   ? 138.026 101.049 88.097  1.00 69.70 ? 501 DST A O4  1 
HETATM 13050 P P1  . DST E 2 .   ? 137.504 102.213 88.795  1.00 69.70 ? 501 DST A P1  1 
HETATM 13051 O O6  . DST E 2 .   ? 138.309 102.303 90.002  1.00 69.70 ? 501 DST A O6  1 
HETATM 13052 O O5  . DST E 2 .   ? 137.926 103.344 87.980  1.00 69.70 ? 501 DST A O5  1 
HETATM 13053 O O2  . DST E 2 .   ? 135.898 102.129 89.100  1.00 69.70 ? 501 DST A O2  1 
HETATM 13054 P P3  . DST E 2 .   ? 135.231 100.761 89.708  1.00 69.70 ? 501 DST A P3  1 
HETATM 13055 O O8  . DST E 2 .   ? 135.976 100.366 90.958  1.00 69.70 ? 501 DST A O8  1 
HETATM 13056 O O7  . DST E 2 .   ? 135.353 99.658  88.689  1.00 69.70 ? 501 DST A O7  1 
HETATM 13057 S S9  . DST E 2 .   ? 133.192 101.107 90.175  1.00 69.70 ? 501 DST A S9  1 
HETATM 13058 C C10 . DST E 2 .   ? 132.210 100.839 88.677  1.00 69.70 ? 501 DST A C10 1 
HETATM 13059 C C11 . DST E 2 .   ? 130.736 100.805 89.053  1.00 69.70 ? 501 DST A C11 1 
HETATM 13060 C C12 . DST E 2 .   ? 130.206 102.228 89.078  1.00 69.70 ? 501 DST A C12 1 
HETATM 13061 C C13 . DST E 2 .   ? 130.603 102.961 87.804  1.00 69.70 ? 501 DST A C13 1 
HETATM 13062 C C14 . DST E 2 .   ? 128.692 102.181 89.196  1.00 69.70 ? 501 DST A C14 1 
HETATM 13063 O O4  . DST F 2 .   ? 89.791  101.045 139.729 1.00 69.44 ? 501 DST B O4  1 
HETATM 13064 P P1  . DST F 2 .   ? 90.333  102.209 139.047 1.00 69.44 ? 501 DST B P1  1 
HETATM 13065 O O6  . DST F 2 .   ? 89.535  102.325 137.837 1.00 69.44 ? 501 DST B O6  1 
HETATM 13066 O O5  . DST F 2 .   ? 89.921  103.335 139.874 1.00 69.44 ? 501 DST B O5  1 
HETATM 13067 O O2  . DST F 2 .   ? 91.942  102.105 138.755 1.00 69.44 ? 501 DST B O2  1 
HETATM 13068 P P3  . DST F 2 .   ? 92.604  100.731 138.151 1.00 69.44 ? 501 DST B P3  1 
HETATM 13069 O O8  . DST F 2 .   ? 91.859  100.347 136.897 1.00 69.44 ? 501 DST B O8  1 
HETATM 13070 O O7  . DST F 2 .   ? 92.467  99.628  139.166 1.00 69.44 ? 501 DST B O7  1 
HETATM 13071 S S9  . DST F 2 .   ? 94.645  101.062 137.680 1.00 69.44 ? 501 DST B S9  1 
HETATM 13072 C C10 . DST F 2 .   ? 95.638  100.863 139.181 1.00 69.44 ? 501 DST B C10 1 
HETATM 13073 C C11 . DST F 2 .   ? 97.108  100.778 138.793 1.00 69.44 ? 501 DST B C11 1 
HETATM 13074 C C12 . DST F 2 .   ? 97.689  102.181 138.737 1.00 69.44 ? 501 DST B C12 1 
HETATM 13075 C C13 . DST F 2 .   ? 97.326  102.946 140.000 1.00 69.44 ? 501 DST B C13 1 
HETATM 13076 C C14 . DST F 2 .   ? 99.202  102.085 138.610 1.00 69.44 ? 501 DST B C14 1 
HETATM 13077 O O4  . DST G 2 .   ? 89.806  126.810 88.134  1.00 69.39 ? 501 DST C O4  1 
HETATM 13078 P P1  . DST G 2 .   ? 90.331  125.631 88.803  1.00 69.39 ? 501 DST C P1  1 
HETATM 13079 O O6  . DST G 2 .   ? 89.530  125.513 90.009  1.00 69.39 ? 501 DST C O6  1 
HETATM 13080 O O5  . DST G 2 .   ? 89.910  124.519 87.963  1.00 69.39 ? 501 DST C O5  1 
HETATM 13081 O O2  . DST G 2 .   ? 91.939  125.712 89.103  1.00 69.39 ? 501 DST C O2  1 
HETATM 13082 P P3  . DST G 2 .   ? 92.609  127.079 89.711  1.00 69.39 ? 501 DST C P3  1 
HETATM 13083 O O8  . DST G 2 .   ? 91.865  127.476 90.962  1.00 69.39 ? 501 DST C O8  1 
HETATM 13084 O O7  . DST G 2 .   ? 92.489  128.182 88.692  1.00 69.39 ? 501 DST C O7  1 
HETATM 13085 S S9  . DST G 2 .   ? 94.647  126.729 90.178  1.00 69.39 ? 501 DST C S9  1 
HETATM 13086 C C10 . DST G 2 .   ? 95.626  126.979 88.674  1.00 69.39 ? 501 DST C C10 1 
HETATM 13087 C C11 . DST G 2 .   ? 97.099  127.026 89.048  1.00 69.39 ? 501 DST C C11 1 
HETATM 13088 C C12 . DST G 2 .   ? 97.640  125.607 89.078  1.00 69.39 ? 501 DST C C12 1 
HETATM 13089 C C13 . DST G 2 .   ? 97.249  124.867 87.806  1.00 69.39 ? 501 DST C C13 1 
HETATM 13090 C C14 . DST G 2 .   ? 99.153  125.665 89.196  1.00 69.39 ? 501 DST C C14 1 
HETATM 13091 O O4  . DST H 2 .   ? 138.026 126.793 139.740 1.00 70.35 ? 501 DST D O4  1 
HETATM 13092 P P1  . DST H 2 .   ? 137.505 125.627 139.044 1.00 70.35 ? 501 DST D P1  1 
HETATM 13093 O O6  . DST H 2 .   ? 138.312 125.535 137.839 1.00 70.35 ? 501 DST D O6  1 
HETATM 13094 O O5  . DST H 2 .   ? 137.926 124.499 139.862 1.00 70.35 ? 501 DST D O5  1 
HETATM 13095 O O2  . DST H 2 .   ? 135.899 125.710 138.738 1.00 70.35 ? 501 DST D O2  1 
HETATM 13096 P P3  . DST H 2 .   ? 135.231 127.079 138.131 1.00 70.35 ? 501 DST D P3  1 
HETATM 13097 O O8  . DST H 2 .   ? 135.976 127.474 136.881 1.00 70.35 ? 501 DST D O8  1 
HETATM 13098 O O7  . DST H 2 .   ? 135.353 128.181 139.150 1.00 70.35 ? 501 DST D O7  1 
HETATM 13099 S S9  . DST H 2 .   ? 133.193 126.733 137.664 1.00 70.35 ? 501 DST D S9  1 
HETATM 13100 C C10 . DST H 2 .   ? 132.211 126.996 139.164 1.00 70.35 ? 501 DST D C10 1 
HETATM 13101 C C11 . DST H 2 .   ? 130.738 127.034 138.788 1.00 70.35 ? 501 DST D C11 1 
HETATM 13102 C C12 . DST H 2 .   ? 130.205 125.612 138.760 1.00 70.35 ? 501 DST D C12 1 
HETATM 13103 C C13 . DST H 2 .   ? 130.600 124.876 140.034 1.00 70.35 ? 501 DST D C13 1 
HETATM 13104 C C14 . DST H 2 .   ? 128.691 125.662 138.642 1.00 70.35 ? 501 DST D C14 1 
# 
