data_8JFW
# 
_entry.id   8JFW 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8JFW         pdb_00008jfw 10.2210/pdb8jfw/pdb 
WWPDB D_1300037791 ?            ?                   
EMDB  EMD-36218    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8JFW 
_pdbx_database_status.recvd_initial_deposition_date   2023-05-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of RDGC/apo-CaM complex' 
_pdbx_database_related.db_id          EMD-36218 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              liuzm@sustech.edu.cn 
_pdbx_contact_author.name_first         Zhongmin 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3280-3890 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Liu, Z.M.' 1 ? 
'Liu, W.'   2 ? 
'Wu, C.'    3 ? 
'Liu, J.'   4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of RDGC/apo-CaM complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, Z.M.' 1 ? 
primary 'Liu, W.'   2 ? 
primary 'Wu, C.'    3 ? 
primary 'Liu, J.'   4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man AT15141p                                    16825.520 1 ?        ? ? ? 
2 polymer     man 'Serine/threonine-protein phosphatase rdgC' 75619.141 1 3.1.3.16 ? ? ? 
3 non-polymer syn 'FE (III) ION'                              55.845    1 ?        ? ? ? 
4 non-polymer syn 'ZINC ION'                                  65.409    1 ?        ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Calmodulin, isoform C'          
2 'Retinal degeneration C protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT
DSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
;
;MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT
DSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
;
A ? 
2 'polypeptide(L)' no no 
;MDENAIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD
KDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLH
GKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYP
RNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSD
PQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQ
LMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPW
RLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVA
HMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRRRSTGRPSVAKTATDPVTLLADKISKNTL
VVEHDIDPTDCESKVIDPKKS
;
;MDENAIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD
KDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLH
GKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYP
RNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSD
PQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQ
LMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPW
RLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVA
HMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRRRSTGRPSVAKTATDPVTLLADKISKNTL
VVEHDIDPTDCESKVIDPKKS
;
D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'FE (III) ION' FE 
4 'ZINC ION'     ZN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ASP n 
1 4   GLN n 
1 5   LEU n 
1 6   THR n 
1 7   GLU n 
1 8   GLU n 
1 9   GLN n 
1 10  ILE n 
1 11  ALA n 
1 12  GLU n 
1 13  PHE n 
1 14  LYS n 
1 15  GLU n 
1 16  ALA n 
1 17  PHE n 
1 18  SER n 
1 19  LEU n 
1 20  PHE n 
1 21  ASP n 
1 22  LYS n 
1 23  ASP n 
1 24  GLY n 
1 25  ASP n 
1 26  GLY n 
1 27  THR n 
1 28  ILE n 
1 29  THR n 
1 30  THR n 
1 31  LYS n 
1 32  GLU n 
1 33  LEU n 
1 34  GLY n 
1 35  THR n 
1 36  VAL n 
1 37  MET n 
1 38  ARG n 
1 39  SER n 
1 40  LEU n 
1 41  GLY n 
1 42  GLN n 
1 43  ASN n 
1 44  PRO n 
1 45  THR n 
1 46  GLU n 
1 47  ALA n 
1 48  GLU n 
1 49  LEU n 
1 50  GLN n 
1 51  ASP n 
1 52  MET n 
1 53  ILE n 
1 54  ASN n 
1 55  GLU n 
1 56  VAL n 
1 57  ASP n 
1 58  ALA n 
1 59  ASP n 
1 60  GLY n 
1 61  ASN n 
1 62  GLY n 
1 63  THR n 
1 64  ILE n 
1 65  ASP n 
1 66  PHE n 
1 67  PRO n 
1 68  GLU n 
1 69  PHE n 
1 70  LEU n 
1 71  THR n 
1 72  MET n 
1 73  MET n 
1 74  ALA n 
1 75  ARG n 
1 76  LYS n 
1 77  MET n 
1 78  LYS n 
1 79  ASP n 
1 80  THR n 
1 81  ASP n 
1 82  SER n 
1 83  GLU n 
1 84  GLU n 
1 85  GLU n 
1 86  ILE n 
1 87  ARG n 
1 88  GLU n 
1 89  ALA n 
1 90  PHE n 
1 91  ARG n 
1 92  VAL n 
1 93  PHE n 
1 94  ASP n 
1 95  LYS n 
1 96  ASP n 
1 97  GLY n 
1 98  ASN n 
1 99  GLY n 
1 100 PHE n 
1 101 ILE n 
1 102 SER n 
1 103 ALA n 
1 104 ALA n 
1 105 GLU n 
1 106 LEU n 
1 107 ARG n 
1 108 HIS n 
1 109 VAL n 
1 110 MET n 
1 111 THR n 
1 112 ASN n 
1 113 LEU n 
1 114 GLY n 
1 115 GLU n 
1 116 LYS n 
1 117 LEU n 
1 118 THR n 
1 119 ASP n 
1 120 GLU n 
1 121 GLU n 
1 122 VAL n 
1 123 ASP n 
1 124 GLU n 
1 125 MET n 
1 126 ILE n 
1 127 ARG n 
1 128 GLU n 
1 129 ALA n 
1 130 ASP n 
1 131 ILE n 
1 132 ASP n 
1 133 GLY n 
1 134 ASP n 
1 135 GLY n 
1 136 GLN n 
1 137 VAL n 
1 138 ASN n 
1 139 TYR n 
1 140 GLU n 
1 141 GLU n 
1 142 PHE n 
1 143 VAL n 
1 144 THR n 
1 145 MET n 
1 146 MET n 
1 147 THR n 
1 148 SER n 
1 149 LYS n 
2 1   MET n 
2 2   ASP n 
2 3   GLU n 
2 4   ASN n 
2 5   ALA n 
2 6   ILE n 
2 7   ARG n 
2 8   ALA n 
2 9   ALA n 
2 10  ILE n 
2 11  PHE n 
2 12  ILE n 
2 13  GLN n 
2 14  LYS n 
2 15  TRP n 
2 16  TYR n 
2 17  ARG n 
2 18  ARG n 
2 19  HIS n 
2 20  GLN n 
2 21  ALA n 
2 22  ARG n 
2 23  ARG n 
2 24  GLU n 
2 25  MET n 
2 26  GLN n 
2 27  ARG n 
2 28  ARG n 
2 29  CYS n 
2 30  ASN n 
2 31  TRP n 
2 32  GLN n 
2 33  ILE n 
2 34  PHE n 
2 35  GLN n 
2 36  ASN n 
2 37  LEU n 
2 38  GLU n 
2 39  TYR n 
2 40  ALA n 
2 41  SER n 
2 42  GLU n 
2 43  GLN n 
2 44  ASP n 
2 45  GLN n 
2 46  ALA n 
2 47  GLU n 
2 48  LEU n 
2 49  TYR n 
2 50  LYS n 
2 51  PHE n 
2 52  PHE n 
2 53  ASN n 
2 54  ASP n 
2 55  LEU n 
2 56  ILE n 
2 57  LYS n 
2 58  HIS n 
2 59  MET n 
2 60  PRO n 
2 61  GLN n 
2 62  ALA n 
2 63  ALA n 
2 64  GLY n 
2 65  ARG n 
2 66  LYS n 
2 67  ASN n 
2 68  GLN n 
2 69  TYR n 
2 70  GLN n 
2 71  GLY n 
2 72  SER n 
2 73  ALA n 
2 74  HIS n 
2 75  VAL n 
2 76  SER n 
2 77  VAL n 
2 78  LEU n 
2 79  ASP n 
2 80  ASP n 
2 81  LYS n 
2 82  ASP n 
2 83  ASP n 
2 84  LEU n 
2 85  VAL n 
2 86  GLU n 
2 87  GLU n 
2 88  PHE n 
2 89  GLY n 
2 90  ASP n 
2 91  ILE n 
2 92  VAL n 
2 93  ASN n 
2 94  ALA n 
2 95  LYS n 
2 96  ILE n 
2 97  GLU n 
2 98  LEU n 
2 99  PRO n 
2 100 ILE n 
2 101 ARG n 
2 102 LYS n 
2 103 ASN n 
2 104 HIS n 
2 105 ILE n 
2 106 ASP n 
2 107 LEU n 
2 108 LEU n 
2 109 ILE n 
2 110 ASP n 
2 111 VAL n 
2 112 PHE n 
2 113 ARG n 
2 114 LYS n 
2 115 LYS n 
2 116 ARG n 
2 117 GLY n 
2 118 ASN n 
2 119 ARG n 
2 120 LEU n 
2 121 HIS n 
2 122 PRO n 
2 123 LYS n 
2 124 TYR n 
2 125 VAL n 
2 126 ALA n 
2 127 LEU n 
2 128 ILE n 
2 129 LEU n 
2 130 ARG n 
2 131 GLU n 
2 132 ALA n 
2 133 ALA n 
2 134 LYS n 
2 135 SER n 
2 136 LEU n 
2 137 LYS n 
2 138 GLN n 
2 139 LEU n 
2 140 PRO n 
2 141 ASN n 
2 142 ILE n 
2 143 SER n 
2 144 PRO n 
2 145 VAL n 
2 146 SER n 
2 147 THR n 
2 148 ALA n 
2 149 VAL n 
2 150 SER n 
2 151 GLN n 
2 152 GLN n 
2 153 VAL n 
2 154 THR n 
2 155 VAL n 
2 156 CYS n 
2 157 GLY n 
2 158 ASP n 
2 159 LEU n 
2 160 HIS n 
2 161 GLY n 
2 162 LYS n 
2 163 LEU n 
2 164 ASP n 
2 165 ASP n 
2 166 LEU n 
2 167 LEU n 
2 168 VAL n 
2 169 VAL n 
2 170 LEU n 
2 171 HIS n 
2 172 LYS n 
2 173 ASN n 
2 174 GLY n 
2 175 LEU n 
2 176 PRO n 
2 177 SER n 
2 178 SER n 
2 179 SER n 
2 180 ASN n 
2 181 PRO n 
2 182 TYR n 
2 183 VAL n 
2 184 PHE n 
2 185 ASN n 
2 186 GLY n 
2 187 ASP n 
2 188 PHE n 
2 189 VAL n 
2 190 ASP n 
2 191 ARG n 
2 192 GLY n 
2 193 LYS n 
2 194 ARG n 
2 195 GLY n 
2 196 LEU n 
2 197 GLU n 
2 198 VAL n 
2 199 LEU n 
2 200 LEU n 
2 201 LEU n 
2 202 LEU n 
2 203 LEU n 
2 204 SER n 
2 205 LEU n 
2 206 TYR n 
2 207 LEU n 
2 208 ALA n 
2 209 PHE n 
2 210 PRO n 
2 211 ASN n 
2 212 ALA n 
2 213 VAL n 
2 214 PHE n 
2 215 LEU n 
2 216 ASN n 
2 217 ARG n 
2 218 GLY n 
2 219 ASN n 
2 220 HIS n 
2 221 GLU n 
2 222 ASP n 
2 223 SER n 
2 224 VAL n 
2 225 MET n 
2 226 ASN n 
2 227 ALA n 
2 228 ARG n 
2 229 TYR n 
2 230 GLY n 
2 231 PHE n 
2 232 ILE n 
2 233 ARG n 
2 234 GLU n 
2 235 VAL n 
2 236 GLU n 
2 237 SER n 
2 238 LYS n 
2 239 TYR n 
2 240 PRO n 
2 241 ARG n 
2 242 ASN n 
2 243 HIS n 
2 244 LYS n 
2 245 ARG n 
2 246 ILE n 
2 247 LEU n 
2 248 ALA n 
2 249 PHE n 
2 250 ILE n 
2 251 ASP n 
2 252 GLU n 
2 253 VAL n 
2 254 TYR n 
2 255 ARG n 
2 256 TRP n 
2 257 LEU n 
2 258 PRO n 
2 259 LEU n 
2 260 GLY n 
2 261 SER n 
2 262 VAL n 
2 263 LEU n 
2 264 ASN n 
2 265 SER n 
2 266 ARG n 
2 267 VAL n 
2 268 LEU n 
2 269 ILE n 
2 270 VAL n 
2 271 HIS n 
2 272 GLY n 
2 273 GLY n 
2 274 PHE n 
2 275 SER n 
2 276 ASP n 
2 277 SER n 
2 278 THR n 
2 279 SER n 
2 280 LEU n 
2 281 ASP n 
2 282 LEU n 
2 283 ILE n 
2 284 LYS n 
2 285 SER n 
2 286 ILE n 
2 287 ASP n 
2 288 ARG n 
2 289 GLY n 
2 290 LYS n 
2 291 TYR n 
2 292 VAL n 
2 293 SER n 
2 294 ILE n 
2 295 LEU n 
2 296 ARG n 
2 297 PRO n 
2 298 PRO n 
2 299 LEU n 
2 300 THR n 
2 301 ASP n 
2 302 GLY n 
2 303 GLU n 
2 304 PRO n 
2 305 LEU n 
2 306 ASP n 
2 307 LYS n 
2 308 THR n 
2 309 GLU n 
2 310 TRP n 
2 311 GLN n 
2 312 GLN n 
2 313 ILE n 
2 314 PHE n 
2 315 ASP n 
2 316 ILE n 
2 317 MET n 
2 318 TRP n 
2 319 SER n 
2 320 ASP n 
2 321 PRO n 
2 322 GLN n 
2 323 ALA n 
2 324 THR n 
2 325 MET n 
2 326 GLY n 
2 327 CYS n 
2 328 VAL n 
2 329 PRO n 
2 330 ASN n 
2 331 THR n 
2 332 LEU n 
2 333 ARG n 
2 334 GLY n 
2 335 ALA n 
2 336 GLY n 
2 337 VAL n 
2 338 TRP n 
2 339 PHE n 
2 340 GLY n 
2 341 PRO n 
2 342 ASP n 
2 343 VAL n 
2 344 THR n 
2 345 ASP n 
2 346 ASN n 
2 347 PHE n 
2 348 LEU n 
2 349 GLN n 
2 350 ARG n 
2 351 HIS n 
2 352 ARG n 
2 353 LEU n 
2 354 SER n 
2 355 TYR n 
2 356 VAL n 
2 357 ILE n 
2 358 ARG n 
2 359 SER n 
2 360 HIS n 
2 361 GLU n 
2 362 CYS n 
2 363 LYS n 
2 364 PRO n 
2 365 ASN n 
2 366 GLY n 
2 367 HIS n 
2 368 GLU n 
2 369 PHE n 
2 370 MET n 
2 371 HIS n 
2 372 ASP n 
2 373 ASN n 
2 374 LYS n 
2 375 ILE n 
2 376 ILE n 
2 377 THR n 
2 378 ILE n 
2 379 PHE n 
2 380 SER n 
2 381 ALA n 
2 382 SER n 
2 383 ASN n 
2 384 TYR n 
2 385 TYR n 
2 386 ALA n 
2 387 ILE n 
2 388 GLY n 
2 389 SER n 
2 390 ASN n 
2 391 LYS n 
2 392 GLY n 
2 393 ALA n 
2 394 TYR n 
2 395 ILE n 
2 396 ARG n 
2 397 LEU n 
2 398 ASN n 
2 399 ASN n 
2 400 GLN n 
2 401 LEU n 
2 402 MET n 
2 403 PRO n 
2 404 HIS n 
2 405 PHE n 
2 406 VAL n 
2 407 GLN n 
2 408 TYR n 
2 409 ILE n 
2 410 SER n 
2 411 ALA n 
2 412 ALA n 
2 413 SER n 
2 414 GLN n 
2 415 THR n 
2 416 LYS n 
2 417 ARG n 
2 418 LEU n 
2 419 SER n 
2 420 PHE n 
2 421 LYS n 
2 422 GLN n 
2 423 ARG n 
2 424 MET n 
2 425 GLY n 
2 426 ILE n 
2 427 VAL n 
2 428 GLU n 
2 429 SER n 
2 430 SER n 
2 431 ALA n 
2 432 LEU n 
2 433 LYS n 
2 434 GLU n 
2 435 LEU n 
2 436 ALA n 
2 437 VAL n 
2 438 ARG n 
2 439 MET n 
2 440 ARG n 
2 441 ASP n 
2 442 HIS n 
2 443 ARG n 
2 444 ASP n 
2 445 GLU n 
2 446 LEU n 
2 447 GLU n 
2 448 ASP n 
2 449 GLU n 
2 450 PHE n 
2 451 ARG n 
2 452 LYS n 
2 453 TYR n 
2 454 ASP n 
2 455 PRO n 
2 456 LYS n 
2 457 ASP n 
2 458 SER n 
2 459 GLY n 
2 460 TYR n 
2 461 ILE n 
2 462 SER n 
2 463 ILE n 
2 464 SER n 
2 465 HIS n 
2 466 TRP n 
2 467 CYS n 
2 468 LYS n 
2 469 VAL n 
2 470 MET n 
2 471 GLU n 
2 472 ASN n 
2 473 VAL n 
2 474 THR n 
2 475 LYS n 
2 476 LEU n 
2 477 GLY n 
2 478 LEU n 
2 479 PRO n 
2 480 TRP n 
2 481 ARG n 
2 482 LEU n 
2 483 LEU n 
2 484 ARG n 
2 485 ASP n 
2 486 LYS n 
2 487 LEU n 
2 488 ALA n 
2 489 PRO n 
2 490 GLY n 
2 491 THR n 
2 492 ASP n 
2 493 SER n 
2 494 GLN n 
2 495 LYS n 
2 496 VAL n 
2 497 ASN n 
2 498 TYR n 
2 499 ASN n 
2 500 ARG n 
2 501 THR n 
2 502 LEU n 
2 503 ASP n 
2 504 LEU n 
2 505 LEU n 
2 506 ASP n 
2 507 THR n 
2 508 ASP n 
2 509 VAL n 
2 510 ILE n 
2 511 LEU n 
2 512 GLU n 
2 513 ALA n 
2 514 GLU n 
2 515 ALA n 
2 516 ASP n 
2 517 GLY n 
2 518 MET n 
2 519 SER n 
2 520 VAL n 
2 521 MET n 
2 522 ASP n 
2 523 ALA n 
2 524 LEU n 
2 525 TYR n 
2 526 ALA n 
2 527 ASN n 
2 528 LYS n 
2 529 ALA n 
2 530 SER n 
2 531 LEU n 
2 532 VAL n 
2 533 ALA n 
2 534 ILE n 
2 535 PHE n 
2 536 ASN n 
2 537 ILE n 
2 538 ILE n 
2 539 ASP n 
2 540 ALA n 
2 541 ASP n 
2 542 ASN n 
2 543 SER n 
2 544 GLY n 
2 545 GLU n 
2 546 ILE n 
2 547 THR n 
2 548 LEU n 
2 549 ASP n 
2 550 GLU n 
2 551 PHE n 
2 552 GLU n 
2 553 THR n 
2 554 ALA n 
2 555 ILE n 
2 556 ASP n 
2 557 LEU n 
2 558 LEU n 
2 559 VAL n 
2 560 ALA n 
2 561 HIS n 
2 562 MET n 
2 563 PRO n 
2 564 GLY n 
2 565 ALA n 
2 566 TYR n 
2 567 SER n 
2 568 LYS n 
2 569 ALA n 
2 570 GLU n 
2 571 MET n 
2 572 LEU n 
2 573 GLU n 
2 574 LYS n 
2 575 CYS n 
2 576 ARG n 
2 577 MET n 
2 578 MET n 
2 579 ASP n 
2 580 LEU n 
2 581 ASN n 
2 582 GLY n 
2 583 ASP n 
2 584 GLY n 
2 585 LYS n 
2 586 VAL n 
2 587 ASP n 
2 588 LEU n 
2 589 ASN n 
2 590 GLU n 
2 591 PHE n 
2 592 LEU n 
2 593 GLU n 
2 594 ALA n 
2 595 PHE n 
2 596 ARG n 
2 597 LEU n 
2 598 SER n 
2 599 ASP n 
2 600 LEU n 
2 601 HIS n 
2 602 ARG n 
2 603 LYS n 
2 604 GLU n 
2 605 GLN n 
2 606 GLN n 
2 607 ASP n 
2 608 GLU n 
2 609 ASN n 
2 610 ILE n 
2 611 ARG n 
2 612 ARG n 
2 613 ARG n 
2 614 SER n 
2 615 THR n 
2 616 GLY n 
2 617 ARG n 
2 618 PRO n 
2 619 SER n 
2 620 VAL n 
2 621 ALA n 
2 622 LYS n 
2 623 THR n 
2 624 ALA n 
2 625 THR n 
2 626 ASP n 
2 627 PRO n 
2 628 VAL n 
2 629 THR n 
2 630 LEU n 
2 631 LEU n 
2 632 ALA n 
2 633 ASP n 
2 634 LYS n 
2 635 ILE n 
2 636 SER n 
2 637 LYS n 
2 638 ASN n 
2 639 THR n 
2 640 LEU n 
2 641 VAL n 
2 642 VAL n 
2 643 GLU n 
2 644 HIS n 
2 645 ASP n 
2 646 ILE n 
2 647 ASP n 
2 648 PRO n 
2 649 THR n 
2 650 ASP n 
2 651 CYS n 
2 652 GLU n 
2 653 SER n 
2 654 LYS n 
2 655 VAL n 
2 656 ILE n 
2 657 ASP n 
2 658 PRO n 
2 659 LYS n 
2 660 LYS n 
2 661 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 149 'fruit fly' ? Cam-RB          ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 661 'fruit fly' ? 'rdgC, CG44746' ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
FE  non-polymer         . 'FE (III) ION'  ? 'Fe 3'           55.845  
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'      ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ASP 3   3   ?   ?   ?   A . n 
A 1 4   GLN 4   4   4   GLN GLN A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   THR 6   6   6   THR THR A . n 
A 1 7   GLU 7   7   7   GLU GLU A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  ILE 10  10  10  ILE ILE A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  LYS 14  14  14  LYS LYS A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  PHE 17  17  17  PHE PHE A . n 
A 1 18  SER 18  18  18  SER SER A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  PHE 20  20  20  PHE PHE A . n 
A 1 21  ASP 21  21  21  ASP ASP A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  ASP 25  25  25  ASP ASP A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  THR 27  27  27  THR THR A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  GLU 32  32  32  GLU GLU A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  MET 37  37  37  MET MET A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  GLN 42  42  42  GLN GLN A . n 
A 1 43  ASN 43  43  43  ASN ASN A . n 
A 1 44  PRO 44  44  44  PRO PRO A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  LEU 49  49  49  LEU LEU A . n 
A 1 50  GLN 50  50  50  GLN GLN A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  MET 52  52  52  MET MET A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  ASN 54  54  54  ASN ASN A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  ALA 58  58  58  ALA ALA A . n 
A 1 59  ASP 59  59  59  ASP ASP A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  PRO 67  67  67  PRO PRO A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  PHE 69  69  69  PHE PHE A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  MET 72  72  72  MET MET A . n 
A 1 73  MET 73  73  73  MET MET A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  ARG 75  75  75  ARG ARG A . n 
A 1 76  LYS 76  76  76  LYS LYS A . n 
A 1 77  MET 77  77  77  MET MET A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  ASP 79  79  79  ASP ASP A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  GLU 83  83  83  GLU GLU A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  GLU 85  85  85  GLU GLU A . n 
A 1 86  ILE 86  86  86  ILE ILE A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  PHE 90  90  90  PHE PHE A . n 
A 1 91  ARG 91  91  91  ARG ARG A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  ASP 94  94  94  ASP ASP A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  ASN 98  98  98  ASN ASN A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 PHE 100 100 100 PHE PHE A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 GLU 105 105 105 GLU GLU A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 ARG 107 107 107 ARG ARG A . n 
A 1 108 HIS 108 108 108 HIS HIS A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 ASN 112 112 112 ASN ASN A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 GLU 115 115 115 GLU GLU A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 THR 118 118 118 THR THR A . n 
A 1 119 ASP 119 119 119 ASP ASP A . n 
A 1 120 GLU 120 120 120 GLU GLU A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 ASP 123 123 123 ASP ASP A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 MET 125 125 125 MET MET A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 GLU 128 128 128 GLU GLU A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 ILE 131 131 131 ILE ILE A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 GLY 135 135 135 GLY GLY A . n 
A 1 136 GLN 136 136 136 GLN GLN A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 ASN 138 138 138 ASN ASN A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 GLU 140 140 140 GLU GLU A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 VAL 143 143 143 VAL VAL A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 MET 145 145 145 MET MET A . n 
A 1 146 MET 146 146 146 MET MET A . n 
A 1 147 THR 147 147 147 THR THR A . n 
A 1 148 SER 148 148 148 SER SER A . n 
A 1 149 LYS 149 149 ?   ?   ?   A . n 
B 2 1   MET 1   1   1   MET MET D . n 
B 2 2   ASP 2   2   2   ASP ASP D . n 
B 2 3   GLU 3   3   3   GLU GLU D . n 
B 2 4   ASN 4   4   4   ASN ASN D . n 
B 2 5   ALA 5   5   5   ALA ALA D . n 
B 2 6   ILE 6   6   6   ILE ILE D . n 
B 2 7   ARG 7   7   7   ARG ARG D . n 
B 2 8   ALA 8   8   8   ALA ALA D . n 
B 2 9   ALA 9   9   9   ALA ALA D . n 
B 2 10  ILE 10  10  10  ILE ILE D . n 
B 2 11  PHE 11  11  11  PHE PHE D . n 
B 2 12  ILE 12  12  12  ILE ILE D . n 
B 2 13  GLN 13  13  13  GLN GLN D . n 
B 2 14  LYS 14  14  14  LYS LYS D . n 
B 2 15  TRP 15  15  15  TRP TRP D . n 
B 2 16  TYR 16  16  16  TYR TYR D . n 
B 2 17  ARG 17  17  17  ARG ARG D . n 
B 2 18  ARG 18  18  18  ARG ARG D . n 
B 2 19  HIS 19  19  19  HIS HIS D . n 
B 2 20  GLN 20  20  20  GLN GLN D . n 
B 2 21  ALA 21  21  21  ALA ALA D . n 
B 2 22  ARG 22  22  22  ARG ARG D . n 
B 2 23  ARG 23  23  23  ARG ARG D . n 
B 2 24  GLU 24  24  24  GLU GLU D . n 
B 2 25  MET 25  25  25  MET MET D . n 
B 2 26  GLN 26  26  26  GLN GLN D . n 
B 2 27  ARG 27  27  27  ARG ARG D . n 
B 2 28  ARG 28  28  28  ARG ARG D . n 
B 2 29  CYS 29  29  29  CYS CYS D . n 
B 2 30  ASN 30  30  30  ASN ASN D . n 
B 2 31  TRP 31  31  31  TRP TRP D . n 
B 2 32  GLN 32  32  32  GLN GLN D . n 
B 2 33  ILE 33  33  33  ILE ILE D . n 
B 2 34  PHE 34  34  34  PHE PHE D . n 
B 2 35  GLN 35  35  35  GLN GLN D . n 
B 2 36  ASN 36  36  36  ASN ASN D . n 
B 2 37  LEU 37  37  37  LEU LEU D . n 
B 2 38  GLU 38  38  38  GLU GLU D . n 
B 2 39  TYR 39  39  39  TYR TYR D . n 
B 2 40  ALA 40  40  40  ALA ALA D . n 
B 2 41  SER 41  41  41  SER SER D . n 
B 2 42  GLU 42  42  42  GLU GLU D . n 
B 2 43  GLN 43  43  43  GLN GLN D . n 
B 2 44  ASP 44  44  44  ASP ASP D . n 
B 2 45  GLN 45  45  45  GLN GLN D . n 
B 2 46  ALA 46  46  46  ALA ALA D . n 
B 2 47  GLU 47  47  47  GLU GLU D . n 
B 2 48  LEU 48  48  48  LEU LEU D . n 
B 2 49  TYR 49  49  49  TYR TYR D . n 
B 2 50  LYS 50  50  50  LYS LYS D . n 
B 2 51  PHE 51  51  51  PHE PHE D . n 
B 2 52  PHE 52  52  52  PHE PHE D . n 
B 2 53  ASN 53  53  53  ASN ASN D . n 
B 2 54  ASP 54  54  54  ASP ASP D . n 
B 2 55  LEU 55  55  55  LEU LEU D . n 
B 2 56  ILE 56  56  56  ILE ILE D . n 
B 2 57  LYS 57  57  57  LYS LYS D . n 
B 2 58  HIS 58  58  58  HIS HIS D . n 
B 2 59  MET 59  59  59  MET MET D . n 
B 2 60  PRO 60  60  60  PRO PRO D . n 
B 2 61  GLN 61  61  61  GLN GLN D . n 
B 2 62  ALA 62  62  ?   ?   ?   D . n 
B 2 63  ALA 63  63  ?   ?   ?   D . n 
B 2 64  GLY 64  64  ?   ?   ?   D . n 
B 2 65  ARG 65  65  ?   ?   ?   D . n 
B 2 66  LYS 66  66  ?   ?   ?   D . n 
B 2 67  ASN 67  67  ?   ?   ?   D . n 
B 2 68  GLN 68  68  ?   ?   ?   D . n 
B 2 69  TYR 69  69  ?   ?   ?   D . n 
B 2 70  GLN 70  70  ?   ?   ?   D . n 
B 2 71  GLY 71  71  ?   ?   ?   D . n 
B 2 72  SER 72  72  ?   ?   ?   D . n 
B 2 73  ALA 73  73  ?   ?   ?   D . n 
B 2 74  HIS 74  74  ?   ?   ?   D . n 
B 2 75  VAL 75  75  ?   ?   ?   D . n 
B 2 76  SER 76  76  ?   ?   ?   D . n 
B 2 77  VAL 77  77  ?   ?   ?   D . n 
B 2 78  LEU 78  78  ?   ?   ?   D . n 
B 2 79  ASP 79  79  ?   ?   ?   D . n 
B 2 80  ASP 80  80  80  ASP ASP D . n 
B 2 81  LYS 81  81  81  LYS LYS D . n 
B 2 82  ASP 82  82  82  ASP ASP D . n 
B 2 83  ASP 83  83  83  ASP ASP D . n 
B 2 84  LEU 84  84  84  LEU LEU D . n 
B 2 85  VAL 85  85  85  VAL VAL D . n 
B 2 86  GLU 86  86  86  GLU GLU D . n 
B 2 87  GLU 87  87  87  GLU GLU D . n 
B 2 88  PHE 88  88  88  PHE PHE D . n 
B 2 89  GLY 89  89  89  GLY GLY D . n 
B 2 90  ASP 90  90  90  ASP ASP D . n 
B 2 91  ILE 91  91  91  ILE ILE D . n 
B 2 92  VAL 92  92  92  VAL VAL D . n 
B 2 93  ASN 93  93  93  ASN ASN D . n 
B 2 94  ALA 94  94  94  ALA ALA D . n 
B 2 95  LYS 95  95  95  LYS LYS D . n 
B 2 96  ILE 96  96  96  ILE ILE D . n 
B 2 97  GLU 97  97  97  GLU GLU D . n 
B 2 98  LEU 98  98  98  LEU LEU D . n 
B 2 99  PRO 99  99  99  PRO PRO D . n 
B 2 100 ILE 100 100 100 ILE ILE D . n 
B 2 101 ARG 101 101 101 ARG ARG D . n 
B 2 102 LYS 102 102 102 LYS LYS D . n 
B 2 103 ASN 103 103 103 ASN ASN D . n 
B 2 104 HIS 104 104 104 HIS HIS D . n 
B 2 105 ILE 105 105 105 ILE ILE D . n 
B 2 106 ASP 106 106 106 ASP ASP D . n 
B 2 107 LEU 107 107 107 LEU LEU D . n 
B 2 108 LEU 108 108 108 LEU LEU D . n 
B 2 109 ILE 109 109 109 ILE ILE D . n 
B 2 110 ASP 110 110 110 ASP ASP D . n 
B 2 111 VAL 111 111 111 VAL VAL D . n 
B 2 112 PHE 112 112 112 PHE PHE D . n 
B 2 113 ARG 113 113 113 ARG ARG D . n 
B 2 114 LYS 114 114 114 LYS LYS D . n 
B 2 115 LYS 115 115 115 LYS LYS D . n 
B 2 116 ARG 116 116 116 ARG ARG D . n 
B 2 117 GLY 117 117 117 GLY GLY D . n 
B 2 118 ASN 118 118 118 ASN ASN D . n 
B 2 119 ARG 119 119 119 ARG ARG D . n 
B 2 120 LEU 120 120 120 LEU LEU D . n 
B 2 121 HIS 121 121 121 HIS HIS D . n 
B 2 122 PRO 122 122 122 PRO PRO D . n 
B 2 123 LYS 123 123 123 LYS LYS D . n 
B 2 124 TYR 124 124 124 TYR TYR D . n 
B 2 125 VAL 125 125 125 VAL VAL D . n 
B 2 126 ALA 126 126 126 ALA ALA D . n 
B 2 127 LEU 127 127 127 LEU LEU D . n 
B 2 128 ILE 128 128 128 ILE ILE D . n 
B 2 129 LEU 129 129 129 LEU LEU D . n 
B 2 130 ARG 130 130 130 ARG ARG D . n 
B 2 131 GLU 131 131 131 GLU GLU D . n 
B 2 132 ALA 132 132 132 ALA ALA D . n 
B 2 133 ALA 133 133 133 ALA ALA D . n 
B 2 134 LYS 134 134 134 LYS LYS D . n 
B 2 135 SER 135 135 135 SER SER D . n 
B 2 136 LEU 136 136 136 LEU LEU D . n 
B 2 137 LYS 137 137 137 LYS LYS D . n 
B 2 138 GLN 138 138 138 GLN GLN D . n 
B 2 139 LEU 139 139 139 LEU LEU D . n 
B 2 140 PRO 140 140 140 PRO PRO D . n 
B 2 141 ASN 141 141 141 ASN ASN D . n 
B 2 142 ILE 142 142 142 ILE ILE D . n 
B 2 143 SER 143 143 143 SER SER D . n 
B 2 144 PRO 144 144 144 PRO PRO D . n 
B 2 145 VAL 145 145 145 VAL VAL D . n 
B 2 146 SER 146 146 146 SER SER D . n 
B 2 147 THR 147 147 147 THR THR D . n 
B 2 148 ALA 148 148 148 ALA ALA D . n 
B 2 149 VAL 149 149 149 VAL VAL D . n 
B 2 150 SER 150 150 150 SER SER D . n 
B 2 151 GLN 151 151 151 GLN GLN D . n 
B 2 152 GLN 152 152 152 GLN GLN D . n 
B 2 153 VAL 153 153 153 VAL VAL D . n 
B 2 154 THR 154 154 154 THR THR D . n 
B 2 155 VAL 155 155 155 VAL VAL D . n 
B 2 156 CYS 156 156 156 CYS CYS D . n 
B 2 157 GLY 157 157 157 GLY GLY D . n 
B 2 158 ASP 158 158 158 ASP ASP D . n 
B 2 159 LEU 159 159 159 LEU LEU D . n 
B 2 160 HIS 160 160 160 HIS HIS D . n 
B 2 161 GLY 161 161 161 GLY GLY D . n 
B 2 162 LYS 162 162 162 LYS LYS D . n 
B 2 163 LEU 163 163 163 LEU LEU D . n 
B 2 164 ASP 164 164 164 ASP ASP D . n 
B 2 165 ASP 165 165 165 ASP ASP D . n 
B 2 166 LEU 166 166 166 LEU LEU D . n 
B 2 167 LEU 167 167 167 LEU LEU D . n 
B 2 168 VAL 168 168 168 VAL VAL D . n 
B 2 169 VAL 169 169 169 VAL VAL D . n 
B 2 170 LEU 170 170 170 LEU LEU D . n 
B 2 171 HIS 171 171 171 HIS HIS D . n 
B 2 172 LYS 172 172 172 LYS LYS D . n 
B 2 173 ASN 173 173 173 ASN ASN D . n 
B 2 174 GLY 174 174 174 GLY GLY D . n 
B 2 175 LEU 175 175 175 LEU LEU D . n 
B 2 176 PRO 176 176 176 PRO PRO D . n 
B 2 177 SER 177 177 177 SER SER D . n 
B 2 178 SER 178 178 178 SER SER D . n 
B 2 179 SER 179 179 179 SER SER D . n 
B 2 180 ASN 180 180 180 ASN ASN D . n 
B 2 181 PRO 181 181 181 PRO PRO D . n 
B 2 182 TYR 182 182 182 TYR TYR D . n 
B 2 183 VAL 183 183 183 VAL VAL D . n 
B 2 184 PHE 184 184 184 PHE PHE D . n 
B 2 185 ASN 185 185 185 ASN ASN D . n 
B 2 186 GLY 186 186 186 GLY GLY D . n 
B 2 187 ASP 187 187 187 ASP ASP D . n 
B 2 188 PHE 188 188 188 PHE PHE D . n 
B 2 189 VAL 189 189 189 VAL VAL D . n 
B 2 190 ASP 190 190 190 ASP ASP D . n 
B 2 191 ARG 191 191 191 ARG ARG D . n 
B 2 192 GLY 192 192 192 GLY GLY D . n 
B 2 193 LYS 193 193 193 LYS LYS D . n 
B 2 194 ARG 194 194 194 ARG ARG D . n 
B 2 195 GLY 195 195 195 GLY GLY D . n 
B 2 196 LEU 196 196 196 LEU LEU D . n 
B 2 197 GLU 197 197 197 GLU GLU D . n 
B 2 198 VAL 198 198 198 VAL VAL D . n 
B 2 199 LEU 199 199 199 LEU LEU D . n 
B 2 200 LEU 200 200 200 LEU LEU D . n 
B 2 201 LEU 201 201 201 LEU LEU D . n 
B 2 202 LEU 202 202 202 LEU LEU D . n 
B 2 203 LEU 203 203 203 LEU LEU D . n 
B 2 204 SER 204 204 204 SER SER D . n 
B 2 205 LEU 205 205 205 LEU LEU D . n 
B 2 206 TYR 206 206 206 TYR TYR D . n 
B 2 207 LEU 207 207 207 LEU LEU D . n 
B 2 208 ALA 208 208 208 ALA ALA D . n 
B 2 209 PHE 209 209 209 PHE PHE D . n 
B 2 210 PRO 210 210 210 PRO PRO D . n 
B 2 211 ASN 211 211 211 ASN ASN D . n 
B 2 212 ALA 212 212 212 ALA ALA D . n 
B 2 213 VAL 213 213 213 VAL VAL D . n 
B 2 214 PHE 214 214 214 PHE PHE D . n 
B 2 215 LEU 215 215 215 LEU LEU D . n 
B 2 216 ASN 216 216 216 ASN ASN D . n 
B 2 217 ARG 217 217 217 ARG ARG D . n 
B 2 218 GLY 218 218 218 GLY GLY D . n 
B 2 219 ASN 219 219 219 ASN ASN D . n 
B 2 220 HIS 220 220 220 HIS HIS D . n 
B 2 221 GLU 221 221 221 GLU GLU D . n 
B 2 222 ASP 222 222 222 ASP ASP D . n 
B 2 223 SER 223 223 223 SER SER D . n 
B 2 224 VAL 224 224 224 VAL VAL D . n 
B 2 225 MET 225 225 225 MET MET D . n 
B 2 226 ASN 226 226 226 ASN ASN D . n 
B 2 227 ALA 227 227 227 ALA ALA D . n 
B 2 228 ARG 228 228 228 ARG ARG D . n 
B 2 229 TYR 229 229 229 TYR TYR D . n 
B 2 230 GLY 230 230 230 GLY GLY D . n 
B 2 231 PHE 231 231 231 PHE PHE D . n 
B 2 232 ILE 232 232 232 ILE ILE D . n 
B 2 233 ARG 233 233 233 ARG ARG D . n 
B 2 234 GLU 234 234 234 GLU GLU D . n 
B 2 235 VAL 235 235 235 VAL VAL D . n 
B 2 236 GLU 236 236 236 GLU GLU D . n 
B 2 237 SER 237 237 237 SER SER D . n 
B 2 238 LYS 238 238 238 LYS LYS D . n 
B 2 239 TYR 239 239 239 TYR TYR D . n 
B 2 240 PRO 240 240 240 PRO PRO D . n 
B 2 241 ARG 241 241 241 ARG ARG D . n 
B 2 242 ASN 242 242 242 ASN ASN D . n 
B 2 243 HIS 243 243 243 HIS HIS D . n 
B 2 244 LYS 244 244 244 LYS LYS D . n 
B 2 245 ARG 245 245 245 ARG ARG D . n 
B 2 246 ILE 246 246 246 ILE ILE D . n 
B 2 247 LEU 247 247 247 LEU LEU D . n 
B 2 248 ALA 248 248 248 ALA ALA D . n 
B 2 249 PHE 249 249 249 PHE PHE D . n 
B 2 250 ILE 250 250 250 ILE ILE D . n 
B 2 251 ASP 251 251 251 ASP ASP D . n 
B 2 252 GLU 252 252 252 GLU GLU D . n 
B 2 253 VAL 253 253 253 VAL VAL D . n 
B 2 254 TYR 254 254 254 TYR TYR D . n 
B 2 255 ARG 255 255 255 ARG ARG D . n 
B 2 256 TRP 256 256 256 TRP TRP D . n 
B 2 257 LEU 257 257 257 LEU LEU D . n 
B 2 258 PRO 258 258 258 PRO PRO D . n 
B 2 259 LEU 259 259 259 LEU LEU D . n 
B 2 260 GLY 260 260 260 GLY GLY D . n 
B 2 261 SER 261 261 261 SER SER D . n 
B 2 262 VAL 262 262 262 VAL VAL D . n 
B 2 263 LEU 263 263 263 LEU LEU D . n 
B 2 264 ASN 264 264 264 ASN ASN D . n 
B 2 265 SER 265 265 265 SER SER D . n 
B 2 266 ARG 266 266 266 ARG ARG D . n 
B 2 267 VAL 267 267 267 VAL VAL D . n 
B 2 268 LEU 268 268 268 LEU LEU D . n 
B 2 269 ILE 269 269 269 ILE ILE D . n 
B 2 270 VAL 270 270 270 VAL VAL D . n 
B 2 271 HIS 271 271 271 HIS HIS D . n 
B 2 272 GLY 272 272 272 GLY GLY D . n 
B 2 273 GLY 273 273 273 GLY GLY D . n 
B 2 274 PHE 274 274 274 PHE PHE D . n 
B 2 275 SER 275 275 275 SER SER D . n 
B 2 276 ASP 276 276 276 ASP ASP D . n 
B 2 277 SER 277 277 277 SER SER D . n 
B 2 278 THR 278 278 278 THR THR D . n 
B 2 279 SER 279 279 279 SER SER D . n 
B 2 280 LEU 280 280 280 LEU LEU D . n 
B 2 281 ASP 281 281 281 ASP ASP D . n 
B 2 282 LEU 282 282 282 LEU LEU D . n 
B 2 283 ILE 283 283 283 ILE ILE D . n 
B 2 284 LYS 284 284 284 LYS LYS D . n 
B 2 285 SER 285 285 285 SER SER D . n 
B 2 286 ILE 286 286 286 ILE ILE D . n 
B 2 287 ASP 287 287 287 ASP ASP D . n 
B 2 288 ARG 288 288 288 ARG ARG D . n 
B 2 289 GLY 289 289 289 GLY GLY D . n 
B 2 290 LYS 290 290 290 LYS LYS D . n 
B 2 291 TYR 291 291 291 TYR TYR D . n 
B 2 292 VAL 292 292 292 VAL VAL D . n 
B 2 293 SER 293 293 293 SER SER D . n 
B 2 294 ILE 294 294 294 ILE ILE D . n 
B 2 295 LEU 295 295 295 LEU LEU D . n 
B 2 296 ARG 296 296 296 ARG ARG D . n 
B 2 297 PRO 297 297 297 PRO PRO D . n 
B 2 298 PRO 298 298 298 PRO PRO D . n 
B 2 299 LEU 299 299 299 LEU LEU D . n 
B 2 300 THR 300 300 300 THR THR D . n 
B 2 301 ASP 301 301 301 ASP ASP D . n 
B 2 302 GLY 302 302 302 GLY GLY D . n 
B 2 303 GLU 303 303 303 GLU GLU D . n 
B 2 304 PRO 304 304 304 PRO PRO D . n 
B 2 305 LEU 305 305 305 LEU LEU D . n 
B 2 306 ASP 306 306 306 ASP ASP D . n 
B 2 307 LYS 307 307 307 LYS LYS D . n 
B 2 308 THR 308 308 308 THR THR D . n 
B 2 309 GLU 309 309 309 GLU GLU D . n 
B 2 310 TRP 310 310 310 TRP TRP D . n 
B 2 311 GLN 311 311 311 GLN GLN D . n 
B 2 312 GLN 312 312 312 GLN GLN D . n 
B 2 313 ILE 313 313 313 ILE ILE D . n 
B 2 314 PHE 314 314 314 PHE PHE D . n 
B 2 315 ASP 315 315 315 ASP ASP D . n 
B 2 316 ILE 316 316 316 ILE ILE D . n 
B 2 317 MET 317 317 317 MET MET D . n 
B 2 318 TRP 318 318 318 TRP TRP D . n 
B 2 319 SER 319 319 319 SER SER D . n 
B 2 320 ASP 320 320 320 ASP ASP D . n 
B 2 321 PRO 321 321 321 PRO PRO D . n 
B 2 322 GLN 322 322 322 GLN GLN D . n 
B 2 323 ALA 323 323 323 ALA ALA D . n 
B 2 324 THR 324 324 324 THR THR D . n 
B 2 325 MET 325 325 325 MET MET D . n 
B 2 326 GLY 326 326 326 GLY GLY D . n 
B 2 327 CYS 327 327 327 CYS CYS D . n 
B 2 328 VAL 328 328 328 VAL VAL D . n 
B 2 329 PRO 329 329 329 PRO PRO D . n 
B 2 330 ASN 330 330 330 ASN ASN D . n 
B 2 331 THR 331 331 331 THR THR D . n 
B 2 332 LEU 332 332 332 LEU LEU D . n 
B 2 333 ARG 333 333 333 ARG ARG D . n 
B 2 334 GLY 334 334 334 GLY GLY D . n 
B 2 335 ALA 335 335 335 ALA ALA D . n 
B 2 336 GLY 336 336 336 GLY GLY D . n 
B 2 337 VAL 337 337 337 VAL VAL D . n 
B 2 338 TRP 338 338 338 TRP TRP D . n 
B 2 339 PHE 339 339 339 PHE PHE D . n 
B 2 340 GLY 340 340 340 GLY GLY D . n 
B 2 341 PRO 341 341 341 PRO PRO D . n 
B 2 342 ASP 342 342 342 ASP ASP D . n 
B 2 343 VAL 343 343 343 VAL VAL D . n 
B 2 344 THR 344 344 344 THR THR D . n 
B 2 345 ASP 345 345 345 ASP ASP D . n 
B 2 346 ASN 346 346 346 ASN ASN D . n 
B 2 347 PHE 347 347 347 PHE PHE D . n 
B 2 348 LEU 348 348 348 LEU LEU D . n 
B 2 349 GLN 349 349 349 GLN GLN D . n 
B 2 350 ARG 350 350 350 ARG ARG D . n 
B 2 351 HIS 351 351 351 HIS HIS D . n 
B 2 352 ARG 352 352 352 ARG ARG D . n 
B 2 353 LEU 353 353 353 LEU LEU D . n 
B 2 354 SER 354 354 354 SER SER D . n 
B 2 355 TYR 355 355 355 TYR TYR D . n 
B 2 356 VAL 356 356 356 VAL VAL D . n 
B 2 357 ILE 357 357 357 ILE ILE D . n 
B 2 358 ARG 358 358 358 ARG ARG D . n 
B 2 359 SER 359 359 359 SER SER D . n 
B 2 360 HIS 360 360 360 HIS HIS D . n 
B 2 361 GLU 361 361 361 GLU GLU D . n 
B 2 362 CYS 362 362 362 CYS CYS D . n 
B 2 363 LYS 363 363 363 LYS LYS D . n 
B 2 364 PRO 364 364 364 PRO PRO D . n 
B 2 365 ASN 365 365 365 ASN ASN D . n 
B 2 366 GLY 366 366 366 GLY GLY D . n 
B 2 367 HIS 367 367 367 HIS HIS D . n 
B 2 368 GLU 368 368 368 GLU GLU D . n 
B 2 369 PHE 369 369 369 PHE PHE D . n 
B 2 370 MET 370 370 370 MET MET D . n 
B 2 371 HIS 371 371 371 HIS HIS D . n 
B 2 372 ASP 372 372 372 ASP ASP D . n 
B 2 373 ASN 373 373 373 ASN ASN D . n 
B 2 374 LYS 374 374 374 LYS LYS D . n 
B 2 375 ILE 375 375 375 ILE ILE D . n 
B 2 376 ILE 376 376 376 ILE ILE D . n 
B 2 377 THR 377 377 377 THR THR D . n 
B 2 378 ILE 378 378 378 ILE ILE D . n 
B 2 379 PHE 379 379 379 PHE PHE D . n 
B 2 380 SER 380 380 380 SER SER D . n 
B 2 381 ALA 381 381 381 ALA ALA D . n 
B 2 382 SER 382 382 382 SER SER D . n 
B 2 383 ASN 383 383 383 ASN ASN D . n 
B 2 384 TYR 384 384 384 TYR TYR D . n 
B 2 385 TYR 385 385 385 TYR TYR D . n 
B 2 386 ALA 386 386 386 ALA ALA D . n 
B 2 387 ILE 387 387 387 ILE ILE D . n 
B 2 388 GLY 388 388 388 GLY GLY D . n 
B 2 389 SER 389 389 389 SER SER D . n 
B 2 390 ASN 390 390 390 ASN ASN D . n 
B 2 391 LYS 391 391 391 LYS LYS D . n 
B 2 392 GLY 392 392 392 GLY GLY D . n 
B 2 393 ALA 393 393 393 ALA ALA D . n 
B 2 394 TYR 394 394 394 TYR TYR D . n 
B 2 395 ILE 395 395 395 ILE ILE D . n 
B 2 396 ARG 396 396 396 ARG ARG D . n 
B 2 397 LEU 397 397 397 LEU LEU D . n 
B 2 398 ASN 398 398 398 ASN ASN D . n 
B 2 399 ASN 399 399 399 ASN ASN D . n 
B 2 400 GLN 400 400 400 GLN GLN D . n 
B 2 401 LEU 401 401 401 LEU LEU D . n 
B 2 402 MET 402 402 402 MET MET D . n 
B 2 403 PRO 403 403 403 PRO PRO D . n 
B 2 404 HIS 404 404 404 HIS HIS D . n 
B 2 405 PHE 405 405 405 PHE PHE D . n 
B 2 406 VAL 406 406 406 VAL VAL D . n 
B 2 407 GLN 407 407 407 GLN GLN D . n 
B 2 408 TYR 408 408 408 TYR TYR D . n 
B 2 409 ILE 409 409 409 ILE ILE D . n 
B 2 410 SER 410 410 410 SER SER D . n 
B 2 411 ALA 411 411 411 ALA ALA D . n 
B 2 412 ALA 412 412 412 ALA ALA D . n 
B 2 413 SER 413 413 413 SER SER D . n 
B 2 414 GLN 414 414 414 GLN GLN D . n 
B 2 415 THR 415 415 415 THR THR D . n 
B 2 416 LYS 416 416 416 LYS LYS D . n 
B 2 417 ARG 417 417 417 ARG ARG D . n 
B 2 418 LEU 418 418 418 LEU LEU D . n 
B 2 419 SER 419 419 419 SER SER D . n 
B 2 420 PHE 420 420 420 PHE PHE D . n 
B 2 421 LYS 421 421 421 LYS LYS D . n 
B 2 422 GLN 422 422 422 GLN GLN D . n 
B 2 423 ARG 423 423 423 ARG ARG D . n 
B 2 424 MET 424 424 424 MET MET D . n 
B 2 425 GLY 425 425 425 GLY GLY D . n 
B 2 426 ILE 426 426 426 ILE ILE D . n 
B 2 427 VAL 427 427 427 VAL VAL D . n 
B 2 428 GLU 428 428 428 GLU GLU D . n 
B 2 429 SER 429 429 429 SER SER D . n 
B 2 430 SER 430 430 430 SER SER D . n 
B 2 431 ALA 431 431 431 ALA ALA D . n 
B 2 432 LEU 432 432 432 LEU LEU D . n 
B 2 433 LYS 433 433 433 LYS LYS D . n 
B 2 434 GLU 434 434 434 GLU GLU D . n 
B 2 435 LEU 435 435 435 LEU LEU D . n 
B 2 436 ALA 436 436 436 ALA ALA D . n 
B 2 437 VAL 437 437 437 VAL VAL D . n 
B 2 438 ARG 438 438 438 ARG ARG D . n 
B 2 439 MET 439 439 439 MET MET D . n 
B 2 440 ARG 440 440 440 ARG ARG D . n 
B 2 441 ASP 441 441 441 ASP ASP D . n 
B 2 442 HIS 442 442 442 HIS HIS D . n 
B 2 443 ARG 443 443 443 ARG ARG D . n 
B 2 444 ASP 444 444 444 ASP ASP D . n 
B 2 445 GLU 445 445 445 GLU GLU D . n 
B 2 446 LEU 446 446 446 LEU LEU D . n 
B 2 447 GLU 447 447 447 GLU GLU D . n 
B 2 448 ASP 448 448 448 ASP ASP D . n 
B 2 449 GLU 449 449 449 GLU GLU D . n 
B 2 450 PHE 450 450 450 PHE PHE D . n 
B 2 451 ARG 451 451 451 ARG ARG D . n 
B 2 452 LYS 452 452 452 LYS LYS D . n 
B 2 453 TYR 453 453 453 TYR TYR D . n 
B 2 454 ASP 454 454 454 ASP ASP D . n 
B 2 455 PRO 455 455 455 PRO PRO D . n 
B 2 456 LYS 456 456 456 LYS LYS D . n 
B 2 457 ASP 457 457 457 ASP ASP D . n 
B 2 458 SER 458 458 458 SER SER D . n 
B 2 459 GLY 459 459 459 GLY GLY D . n 
B 2 460 TYR 460 460 460 TYR TYR D . n 
B 2 461 ILE 461 461 461 ILE ILE D . n 
B 2 462 SER 462 462 462 SER SER D . n 
B 2 463 ILE 463 463 463 ILE ILE D . n 
B 2 464 SER 464 464 464 SER SER D . n 
B 2 465 HIS 465 465 465 HIS HIS D . n 
B 2 466 TRP 466 466 466 TRP TRP D . n 
B 2 467 CYS 467 467 467 CYS CYS D . n 
B 2 468 LYS 468 468 468 LYS LYS D . n 
B 2 469 VAL 469 469 469 VAL VAL D . n 
B 2 470 MET 470 470 470 MET MET D . n 
B 2 471 GLU 471 471 471 GLU GLU D . n 
B 2 472 ASN 472 472 472 ASN ASN D . n 
B 2 473 VAL 473 473 473 VAL VAL D . n 
B 2 474 THR 474 474 474 THR THR D . n 
B 2 475 LYS 475 475 475 LYS LYS D . n 
B 2 476 LEU 476 476 476 LEU LEU D . n 
B 2 477 GLY 477 477 477 GLY GLY D . n 
B 2 478 LEU 478 478 478 LEU LEU D . n 
B 2 479 PRO 479 479 479 PRO PRO D . n 
B 2 480 TRP 480 480 480 TRP TRP D . n 
B 2 481 ARG 481 481 481 ARG ARG D . n 
B 2 482 LEU 482 482 482 LEU LEU D . n 
B 2 483 LEU 483 483 483 LEU LEU D . n 
B 2 484 ARG 484 484 484 ARG ARG D . n 
B 2 485 ASP 485 485 485 ASP ASP D . n 
B 2 486 LYS 486 486 486 LYS LYS D . n 
B 2 487 LEU 487 487 487 LEU LEU D . n 
B 2 488 ALA 488 488 488 ALA ALA D . n 
B 2 489 PRO 489 489 489 PRO PRO D . n 
B 2 490 GLY 490 490 490 GLY GLY D . n 
B 2 491 THR 491 491 491 THR THR D . n 
B 2 492 ASP 492 492 492 ASP ASP D . n 
B 2 493 SER 493 493 493 SER SER D . n 
B 2 494 GLN 494 494 494 GLN GLN D . n 
B 2 495 LYS 495 495 495 LYS LYS D . n 
B 2 496 VAL 496 496 496 VAL VAL D . n 
B 2 497 ASN 497 497 497 ASN ASN D . n 
B 2 498 TYR 498 498 498 TYR TYR D . n 
B 2 499 ASN 499 499 499 ASN ASN D . n 
B 2 500 ARG 500 500 500 ARG ARG D . n 
B 2 501 THR 501 501 501 THR THR D . n 
B 2 502 LEU 502 502 502 LEU LEU D . n 
B 2 503 ASP 503 503 503 ASP ASP D . n 
B 2 504 LEU 504 504 504 LEU LEU D . n 
B 2 505 LEU 505 505 505 LEU LEU D . n 
B 2 506 ASP 506 506 506 ASP ASP D . n 
B 2 507 THR 507 507 507 THR THR D . n 
B 2 508 ASP 508 508 508 ASP ASP D . n 
B 2 509 VAL 509 509 509 VAL VAL D . n 
B 2 510 ILE 510 510 510 ILE ILE D . n 
B 2 511 LEU 511 511 511 LEU LEU D . n 
B 2 512 GLU 512 512 512 GLU GLU D . n 
B 2 513 ALA 513 513 513 ALA ALA D . n 
B 2 514 GLU 514 514 514 GLU GLU D . n 
B 2 515 ALA 515 515 515 ALA ALA D . n 
B 2 516 ASP 516 516 516 ASP ASP D . n 
B 2 517 GLY 517 517 517 GLY GLY D . n 
B 2 518 MET 518 518 518 MET MET D . n 
B 2 519 SER 519 519 519 SER SER D . n 
B 2 520 VAL 520 520 520 VAL VAL D . n 
B 2 521 MET 521 521 521 MET MET D . n 
B 2 522 ASP 522 522 522 ASP ASP D . n 
B 2 523 ALA 523 523 523 ALA ALA D . n 
B 2 524 LEU 524 524 524 LEU LEU D . n 
B 2 525 TYR 525 525 525 TYR TYR D . n 
B 2 526 ALA 526 526 526 ALA ALA D . n 
B 2 527 ASN 527 527 527 ASN ASN D . n 
B 2 528 LYS 528 528 528 LYS LYS D . n 
B 2 529 ALA 529 529 529 ALA ALA D . n 
B 2 530 SER 530 530 530 SER SER D . n 
B 2 531 LEU 531 531 531 LEU LEU D . n 
B 2 532 VAL 532 532 532 VAL VAL D . n 
B 2 533 ALA 533 533 533 ALA ALA D . n 
B 2 534 ILE 534 534 534 ILE ILE D . n 
B 2 535 PHE 535 535 535 PHE PHE D . n 
B 2 536 ASN 536 536 536 ASN ASN D . n 
B 2 537 ILE 537 537 537 ILE ILE D . n 
B 2 538 ILE 538 538 538 ILE ILE D . n 
B 2 539 ASP 539 539 539 ASP ASP D . n 
B 2 540 ALA 540 540 540 ALA ALA D . n 
B 2 541 ASP 541 541 541 ASP ASP D . n 
B 2 542 ASN 542 542 542 ASN ASN D . n 
B 2 543 SER 543 543 543 SER SER D . n 
B 2 544 GLY 544 544 544 GLY GLY D . n 
B 2 545 GLU 545 545 545 GLU GLU D . n 
B 2 546 ILE 546 546 546 ILE ILE D . n 
B 2 547 THR 547 547 547 THR THR D . n 
B 2 548 LEU 548 548 548 LEU LEU D . n 
B 2 549 ASP 549 549 549 ASP ASP D . n 
B 2 550 GLU 550 550 550 GLU GLU D . n 
B 2 551 PHE 551 551 551 PHE PHE D . n 
B 2 552 GLU 552 552 552 GLU GLU D . n 
B 2 553 THR 553 553 553 THR THR D . n 
B 2 554 ALA 554 554 554 ALA ALA D . n 
B 2 555 ILE 555 555 555 ILE ILE D . n 
B 2 556 ASP 556 556 556 ASP ASP D . n 
B 2 557 LEU 557 557 557 LEU LEU D . n 
B 2 558 LEU 558 558 558 LEU LEU D . n 
B 2 559 VAL 559 559 559 VAL VAL D . n 
B 2 560 ALA 560 560 560 ALA ALA D . n 
B 2 561 HIS 561 561 561 HIS HIS D . n 
B 2 562 MET 562 562 562 MET MET D . n 
B 2 563 PRO 563 563 563 PRO PRO D . n 
B 2 564 GLY 564 564 564 GLY GLY D . n 
B 2 565 ALA 565 565 565 ALA ALA D . n 
B 2 566 TYR 566 566 566 TYR TYR D . n 
B 2 567 SER 567 567 567 SER SER D . n 
B 2 568 LYS 568 568 568 LYS LYS D . n 
B 2 569 ALA 569 569 569 ALA ALA D . n 
B 2 570 GLU 570 570 570 GLU GLU D . n 
B 2 571 MET 571 571 571 MET MET D . n 
B 2 572 LEU 572 572 572 LEU LEU D . n 
B 2 573 GLU 573 573 573 GLU GLU D . n 
B 2 574 LYS 574 574 574 LYS LYS D . n 
B 2 575 CYS 575 575 575 CYS CYS D . n 
B 2 576 ARG 576 576 576 ARG ARG D . n 
B 2 577 MET 577 577 577 MET MET D . n 
B 2 578 MET 578 578 578 MET MET D . n 
B 2 579 ASP 579 579 579 ASP ASP D . n 
B 2 580 LEU 580 580 580 LEU LEU D . n 
B 2 581 ASN 581 581 581 ASN ASN D . n 
B 2 582 GLY 582 582 582 GLY GLY D . n 
B 2 583 ASP 583 583 583 ASP ASP D . n 
B 2 584 GLY 584 584 584 GLY GLY D . n 
B 2 585 LYS 585 585 585 LYS LYS D . n 
B 2 586 VAL 586 586 586 VAL VAL D . n 
B 2 587 ASP 587 587 587 ASP ASP D . n 
B 2 588 LEU 588 588 588 LEU LEU D . n 
B 2 589 ASN 589 589 589 ASN ASN D . n 
B 2 590 GLU 590 590 590 GLU GLU D . n 
B 2 591 PHE 591 591 591 PHE PHE D . n 
B 2 592 LEU 592 592 592 LEU LEU D . n 
B 2 593 GLU 593 593 593 GLU GLU D . n 
B 2 594 ALA 594 594 594 ALA ALA D . n 
B 2 595 PHE 595 595 595 PHE PHE D . n 
B 2 596 ARG 596 596 596 ARG ARG D . n 
B 2 597 LEU 597 597 597 LEU LEU D . n 
B 2 598 SER 598 598 598 SER SER D . n 
B 2 599 ASP 599 599 599 ASP ASP D . n 
B 2 600 LEU 600 600 600 LEU LEU D . n 
B 2 601 HIS 601 601 601 HIS HIS D . n 
B 2 602 ARG 602 602 602 ARG ARG D . n 
B 2 603 LYS 603 603 603 LYS LYS D . n 
B 2 604 GLU 604 604 604 GLU GLU D . n 
B 2 605 GLN 605 605 605 GLN GLN D . n 
B 2 606 GLN 606 606 606 GLN GLN D . n 
B 2 607 ASP 607 607 607 ASP ASP D . n 
B 2 608 GLU 608 608 608 GLU GLU D . n 
B 2 609 ASN 609 609 609 ASN ASN D . n 
B 2 610 ILE 610 610 610 ILE ILE D . n 
B 2 611 ARG 611 611 611 ARG ARG D . n 
B 2 612 ARG 612 612 612 ARG ARG D . n 
B 2 613 ARG 613 613 613 ARG ARG D . n 
B 2 614 SER 614 614 ?   ?   ?   D . n 
B 2 615 THR 615 615 ?   ?   ?   D . n 
B 2 616 GLY 616 616 ?   ?   ?   D . n 
B 2 617 ARG 617 617 ?   ?   ?   D . n 
B 2 618 PRO 618 618 ?   ?   ?   D . n 
B 2 619 SER 619 619 ?   ?   ?   D . n 
B 2 620 VAL 620 620 ?   ?   ?   D . n 
B 2 621 ALA 621 621 ?   ?   ?   D . n 
B 2 622 LYS 622 622 ?   ?   ?   D . n 
B 2 623 THR 623 623 ?   ?   ?   D . n 
B 2 624 ALA 624 624 ?   ?   ?   D . n 
B 2 625 THR 625 625 ?   ?   ?   D . n 
B 2 626 ASP 626 626 ?   ?   ?   D . n 
B 2 627 PRO 627 627 ?   ?   ?   D . n 
B 2 628 VAL 628 628 ?   ?   ?   D . n 
B 2 629 THR 629 629 ?   ?   ?   D . n 
B 2 630 LEU 630 630 ?   ?   ?   D . n 
B 2 631 LEU 631 631 ?   ?   ?   D . n 
B 2 632 ALA 632 632 ?   ?   ?   D . n 
B 2 633 ASP 633 633 ?   ?   ?   D . n 
B 2 634 LYS 634 634 ?   ?   ?   D . n 
B 2 635 ILE 635 635 ?   ?   ?   D . n 
B 2 636 SER 636 636 ?   ?   ?   D . n 
B 2 637 LYS 637 637 ?   ?   ?   D . n 
B 2 638 ASN 638 638 ?   ?   ?   D . n 
B 2 639 THR 639 639 ?   ?   ?   D . n 
B 2 640 LEU 640 640 ?   ?   ?   D . n 
B 2 641 VAL 641 641 ?   ?   ?   D . n 
B 2 642 VAL 642 642 ?   ?   ?   D . n 
B 2 643 GLU 643 643 ?   ?   ?   D . n 
B 2 644 HIS 644 644 644 HIS HIS D . n 
B 2 645 ASP 645 645 645 ASP ASP D . n 
B 2 646 ILE 646 646 646 ILE ILE D . n 
B 2 647 ASP 647 647 647 ASP ASP D . n 
B 2 648 PRO 648 648 648 PRO PRO D . n 
B 2 649 THR 649 649 649 THR THR D . n 
B 2 650 ASP 650 650 650 ASP ASP D . n 
B 2 651 CYS 651 651 651 CYS CYS D . n 
B 2 652 GLU 652 652 652 GLU GLU D . n 
B 2 653 SER 653 653 653 SER SER D . n 
B 2 654 LYS 654 654 654 LYS LYS D . n 
B 2 655 VAL 655 655 655 VAL VAL D . n 
B 2 656 ILE 656 656 656 ILE ILE D . n 
B 2 657 ASP 657 657 657 ASP ASP D . n 
B 2 658 PRO 658 658 658 PRO PRO D . n 
B 2 659 LYS 659 659 659 LYS LYS D . n 
B 2 660 LYS 660 660 660 LYS LYS D . n 
B 2 661 SER 661 661 661 SER SER D . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 FE ? ? FE ? ? 'SUBJECT OF INVESTIGATION' ? 
2 ZN ? ? ZN ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 FE 1 701 701 FE FE D . 
D 4 ZN 1 702 702 ZN ZN D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LEU 5   ? CG  ? A LEU 5   CG  
2  1 Y 1 A LEU 5   ? CD1 ? A LEU 5   CD1 
3  1 Y 1 A LEU 5   ? CD2 ? A LEU 5   CD2 
4  1 Y 1 A GLU 7   ? CG  ? A GLU 7   CG  
5  1 Y 1 A GLU 7   ? CD  ? A GLU 7   CD  
6  1 Y 1 A GLU 7   ? OE1 ? A GLU 7   OE1 
7  1 Y 1 A GLU 7   ? OE2 ? A GLU 7   OE2 
8  1 Y 1 A GLU 8   ? CG  ? A GLU 8   CG  
9  1 Y 1 A GLU 8   ? CD  ? A GLU 8   CD  
10 1 Y 1 A GLU 8   ? OE1 ? A GLU 8   OE1 
11 1 Y 1 A GLU 8   ? OE2 ? A GLU 8   OE2 
12 1 Y 1 A LYS 14  ? CG  ? A LYS 14  CG  
13 1 Y 1 A LYS 14  ? CD  ? A LYS 14  CD  
14 1 Y 1 A LYS 14  ? CE  ? A LYS 14  CE  
15 1 Y 1 A LYS 14  ? NZ  ? A LYS 14  NZ  
16 1 Y 1 A LYS 22  ? CG  ? A LYS 22  CG  
17 1 Y 1 A LYS 22  ? CD  ? A LYS 22  CD  
18 1 Y 1 A LYS 22  ? CE  ? A LYS 22  CE  
19 1 Y 1 A LYS 22  ? NZ  ? A LYS 22  NZ  
20 1 Y 1 A ARG 75  ? NE  ? A ARG 75  NE  
21 1 Y 1 A ARG 75  ? CZ  ? A ARG 75  CZ  
22 1 Y 1 A ARG 75  ? NH1 ? A ARG 75  NH1 
23 1 Y 1 A ARG 75  ? NH2 ? A ARG 75  NH2 
24 1 Y 1 A ARG 91  ? NE  ? A ARG 91  NE  
25 1 Y 1 A ARG 91  ? CZ  ? A ARG 91  CZ  
26 1 Y 1 A ARG 91  ? NH1 ? A ARG 91  NH1 
27 1 Y 1 A ARG 91  ? NH2 ? A ARG 91  NH2 
28 1 Y 1 A GLU 140 ? CG  ? A GLU 140 CG  
29 1 Y 1 A GLU 140 ? CD  ? A GLU 140 CD  
30 1 Y 1 A GLU 140 ? OE1 ? A GLU 140 OE1 
31 1 Y 1 A GLU 140 ? OE2 ? A GLU 140 OE2 
32 1 Y 1 A SER 148 ? OG  ? A SER 148 OG  
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.20.1_4487: 
_software.pdbx_ordinal           1 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8JFW 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8JFW 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8JFW 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8JFW 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 6190 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.516 ? 8354 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.923 ? 826  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040 ? 912  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1102 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8JFW 
_struct.title                        'Cryo-EM structure of RDGC/apo-CaM complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8JFW 
_struct_keywords.text            'Phosphatase, metal binding., HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP C6SUZ2_DROME C6SUZ2 ? 1 
;MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDT
DSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
;
11 
2 UNP RDGC_DROME   P40421 ? 2 
;MDENAIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDD
KDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLH
GKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYP
RNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSD
PQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQ
LMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPW
RLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVA
HMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRRRSTGRPSVAKTATDPVTLLADKISKNTL
VVEHDIDPTDCESKVIDPKKS
;
1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8JFW A 1 ? 149 ? C6SUZ2 11 ? 159 ? 1 149 
2 2 8JFW D 1 ? 661 ? P40421 1  ? 661 ? 1 661 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 8   ? SER A 18  ? GLU A 8   SER A 18  1 ? 11 
HELX_P HELX_P2  AA2 GLU A 32  ? LEU A 40  ? GLU A 32  LEU A 40  1 ? 9  
HELX_P HELX_P3  AA3 THR A 45  ? GLU A 55  ? THR A 45  GLU A 55  1 ? 11 
HELX_P HELX_P4  AA4 ASP A 65  ? MET A 77  ? ASP A 65  MET A 77  1 ? 13 
HELX_P HELX_P5  AA5 GLU A 84  ? VAL A 92  ? GLU A 84  VAL A 92  1 ? 9  
HELX_P HELX_P6  AA6 SER A 102 ? LEU A 113 ? SER A 102 LEU A 113 1 ? 12 
HELX_P HELX_P7  AA7 THR A 118 ? ALA A 129 ? THR A 118 ALA A 129 1 ? 12 
HELX_P HELX_P8  AA8 ASN A 138 ? SER A 148 ? ASN A 138 SER A 148 1 ? 11 
HELX_P HELX_P9  AA9 ASP B 2   ? ALA B 46  ? ASP D 2   ALA D 46  1 ? 45 
HELX_P HELX_P10 AB1 ALA B 46  ? MET B 59  ? ALA D 46  MET D 59  1 ? 14 
HELX_P HELX_P11 AB2 ARG B 101 ? LYS B 114 ? ARG D 101 LYS D 114 1 ? 14 
HELX_P HELX_P12 AB3 HIS B 121 ? LYS B 137 ? HIS D 121 LYS D 137 1 ? 17 
HELX_P HELX_P13 AB4 LYS B 162 ? GLY B 174 ? LYS D 162 GLY D 174 1 ? 13 
HELX_P HELX_P14 AB5 ARG B 194 ? PHE B 209 ? ARG D 194 PHE D 209 1 ? 16 
HELX_P HELX_P15 AB6 ASP B 222 ? ALA B 227 ? ASP D 222 ALA D 227 1 ? 6  
HELX_P HELX_P16 AB7 GLY B 230 ? TYR B 239 ? GLY D 230 TYR D 239 1 ? 10 
HELX_P HELX_P17 AB8 ASN B 242 ? TRP B 256 ? ASN D 242 TRP D 256 1 ? 15 
HELX_P HELX_P18 AB9 SER B 279 ? LYS B 284 ? SER D 279 LYS D 284 1 ? 6  
HELX_P HELX_P19 AC1 SER B 285 ? ILE B 286 ? SER D 285 ILE D 286 5 ? 2  
HELX_P HELX_P20 AC2 ASP B 287 ? TYR B 291 ? ASP D 287 TYR D 291 5 ? 5  
HELX_P HELX_P21 AC3 ASP B 306 ? SER B 319 ? ASP D 306 SER D 319 1 ? 14 
HELX_P HELX_P22 AC4 GLY B 340 ? ARG B 352 ? GLY D 340 ARG D 352 1 ? 13 
HELX_P HELX_P23 AC5 ALA B 411 ? LYS B 416 ? ALA D 411 LYS D 416 1 ? 6  
HELX_P HELX_P24 AC6 SER B 419 ? ARG B 440 ? SER D 419 ARG D 440 1 ? 22 
HELX_P HELX_P25 AC7 HIS B 442 ? TYR B 453 ? HIS D 442 TYR D 453 1 ? 12 
HELX_P HELX_P26 AC8 ILE B 463 ? LYS B 475 ? ILE D 463 LYS D 475 1 ? 13 
HELX_P HELX_P27 AC9 PRO B 479 ? LEU B 482 ? PRO D 479 LEU D 482 5 ? 4  
HELX_P HELX_P28 AD1 LEU B 483 ? ALA B 488 ? LEU D 483 ALA D 488 1 ? 6  
HELX_P HELX_P29 AD2 TYR B 498 ? ASP B 506 ? TYR D 498 ASP D 506 1 ? 9  
HELX_P HELX_P30 AD3 THR B 507 ? GLY B 517 ? THR D 507 GLY D 517 1 ? 11 
HELX_P HELX_P31 AD4 ASP B 522 ? ASN B 527 ? ASP D 522 ASN D 527 1 ? 6  
HELX_P HELX_P32 AD5 ASN B 527 ? ILE B 538 ? ASN D 527 ILE D 538 1 ? 12 
HELX_P HELX_P33 AD6 THR B 547 ? MET B 562 ? THR D 547 MET D 562 1 ? 16 
HELX_P HELX_P34 AD7 ALA B 569 ? ASP B 579 ? ALA D 569 ASP D 579 1 ? 11 
HELX_P HELX_P35 AD8 ASP B 587 ? ARG B 612 ? ASP D 587 ARG D 612 1 ? 26 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? B ASP 158 OD2 ? ? ? 1_555 C FE . FE ? ? D ASP 158 D FE 701 1_555 ? ? ? ? ? ? ? 2.365 ? ? 
metalc2 metalc ? ? B HIS 160 NE2 ? ? ? 1_555 C FE . FE ? ? D HIS 160 D FE 701 1_555 ? ? ? ? ? ? ? 2.176 ? ? 
metalc3 metalc ? ? B ASP 187 OD2 ? ? ? 1_555 C FE . FE ? ? D ASP 187 D FE 701 1_555 ? ? ? ? ? ? ? 2.118 ? ? 
metalc4 metalc ? ? B ASP 187 OD2 ? ? ? 1_555 D ZN . ZN ? ? D ASP 187 D ZN 702 1_555 ? ? ? ? ? ? ? 2.070 ? ? 
metalc5 metalc ? ? B ASN 219 OD1 ? ? ? 1_555 D ZN . ZN ? ? D ASN 219 D ZN 702 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
metalc6 metalc ? ? B HIS 271 NE2 ? ? ? 1_555 D ZN . ZN ? ? D HIS 271 D ZN 702 1_555 ? ? ? ? ? ? ? 2.298 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD2 ? B ASP 158 ? D ASP 158 ? 1_555 FE ? C FE . ? D FE 701 ? 1_555 NE2 ? B HIS 160 ? D HIS 160 ? 1_555 119.0 ? 
2 OD2 ? B ASP 158 ? D ASP 158 ? 1_555 FE ? C FE . ? D FE 701 ? 1_555 OD2 ? B ASP 187 ? D ASP 187 ? 1_555 79.0  ? 
3 NE2 ? B HIS 160 ? D HIS 160 ? 1_555 FE ? C FE . ? D FE 701 ? 1_555 OD2 ? B ASP 187 ? D ASP 187 ? 1_555 119.0 ? 
4 OD2 ? B ASP 187 ? D ASP 187 ? 1_555 ZN ? D ZN . ? D ZN 702 ? 1_555 OD1 ? B ASN 219 ? D ASN 219 ? 1_555 106.9 ? 
5 OD2 ? B ASP 187 ? D ASP 187 ? 1_555 ZN ? D ZN . ? D ZN 702 ? 1_555 NE2 ? B HIS 271 ? D HIS 271 ? 1_555 103.3 ? 
6 OD1 ? B ASN 219 ? D ASN 219 ? 1_555 ZN ? D ZN . ? D ZN 702 ? 1_555 NE2 ? B HIS 271 ? D HIS 271 ? 1_555 62.3  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 6 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 28  ? THR A 29  ? ILE A 28  THR A 29  
AA1 2 THR A 63  ? ILE A 64  ? THR A 63  ILE A 64  
AA2 1 ILE B 142 ? VAL B 145 ? ILE D 142 VAL D 145 
AA2 2 GLY B 260 ? LEU B 263 ? GLY D 260 LEU D 263 
AA2 3 VAL B 267 ? ILE B 269 ? VAL D 267 ILE D 269 
AA2 4 VAL B 356 ? ARG B 358 ? VAL D 356 ARG D 358 
AA2 5 ILE B 375 ? ILE B 378 ? ILE D 375 ILE D 378 
AA2 6 HIS B 367 ? MET B 370 ? HIS D 367 MET D 370 
AA3 1 VAL B 213 ? LEU B 215 ? VAL D 213 LEU D 215 
AA3 2 TYR B 182 ? PHE B 184 ? TYR D 182 PHE D 184 
AA3 3 VAL B 153 ? CYS B 156 ? VAL D 153 CYS D 156 
AA3 4 GLY B 392 ? LEU B 397 ? GLY D 392 LEU D 397 
AA3 5 PRO B 403 ? SER B 410 ? PRO D 403 SER D 410 
AA3 6 CYS B 651 ? ILE B 656 ? CYS D 651 ILE D 656 
AA4 1 ASP B 320 ? PRO B 321 ? ASP D 320 PRO D 321 
AA4 2 VAL B 337 ? PHE B 339 ? VAL D 337 PHE D 339 
AA4 3 CYS B 327 ? PRO B 329 ? CYS D 327 PRO D 329 
AA5 1 TYR B 460 ? SER B 462 ? TYR D 460 SER D 462 
AA5 2 LYS B 495 ? ASN B 497 ? LYS D 495 ASN D 497 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 28  ? N ILE A 28  O ILE A 64  ? O ILE A 64  
AA2 1 2 N VAL B 145 ? N VAL D 145 O VAL B 262 ? O VAL D 262 
AA2 2 3 N LEU B 263 ? N LEU D 263 O VAL B 267 ? O VAL D 267 
AA2 3 4 N LEU B 268 ? N LEU D 268 O ILE B 357 ? O ILE D 357 
AA2 4 5 N ARG B 358 ? N ARG D 358 O ILE B 376 ? O ILE D 376 
AA2 5 6 O THR B 377 ? O THR D 377 N GLU B 368 ? N GLU D 368 
AA3 1 2 O PHE B 214 ? O PHE D 214 N PHE B 184 ? N PHE D 184 
AA3 2 3 O VAL B 183 ? O VAL D 183 N CYS B 156 ? N CYS D 156 
AA3 3 4 N VAL B 153 ? N VAL D 153 O LEU B 397 ? O LEU D 397 
AA3 4 5 N ARG B 396 ? N ARG D 396 O HIS B 404 ? O HIS D 404 
AA3 5 6 N PHE B 405 ? N PHE D 405 O ILE B 656 ? O ILE D 656 
AA4 1 2 N ASP B 320 ? N ASP D 320 O VAL B 337 ? O VAL D 337 
AA4 2 3 O TRP B 338 ? O TRP D 338 N VAL B 328 ? N VAL D 328 
AA5 1 2 N ILE B 461 ? N ILE D 461 O VAL B 496 ? O VAL D 496 
# 
_pdbx_entry_details.entry_id                   8JFW 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG1 
_pdbx_validate_close_contact.auth_asym_id_1   D 
_pdbx_validate_close_contact.auth_comp_id_1   THR 
_pdbx_validate_close_contact.auth_seq_id_1    547 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OD2 
_pdbx_validate_close_contact.auth_asym_id_2   D 
_pdbx_validate_close_contact.auth_comp_id_2   ASP 
_pdbx_validate_close_contact.auth_seq_id_2    549 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.11 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             D 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              329 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             D 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              329 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CD 
_pdbx_validate_rmsd_angle.auth_asym_id_3             D 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              329 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                102.42 
_pdbx_validate_rmsd_angle.angle_target_value         111.70 
_pdbx_validate_rmsd_angle.angle_deviation            -9.28 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.40 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 40  ? ? -99.27  32.35   
2  1 GLN D 152 ? ? -170.78 142.99  
3  1 ASN D 180 ? ? -156.94 69.62   
4  1 ASN D 185 ? ? -94.93  54.50   
5  1 ASP D 190 ? ? 82.29   12.15   
6  1 PHE D 274 ? ? -161.24 -169.15 
7  1 ASP D 301 ? ? -92.12  54.07   
8  1 SER D 359 ? ? -141.47 13.21   
9  1 PHE D 379 ? ? -160.63 115.75  
10 1 MET D 521 ? ? 69.93   -144.78 
11 1 LEU D 588 ? ? 54.61   -141.81 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8JFW 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8JFW 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.64 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               202878 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of RDGC/apo-CaM complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8JFW 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8JFW 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8JFW 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A ASP 3   ? A ASP 3   
4  1 Y 1 A LYS 149 ? A LYS 149 
5  1 Y 1 D ALA 62  ? B ALA 62  
6  1 Y 1 D ALA 63  ? B ALA 63  
7  1 Y 1 D GLY 64  ? B GLY 64  
8  1 Y 1 D ARG 65  ? B ARG 65  
9  1 Y 1 D LYS 66  ? B LYS 66  
10 1 Y 1 D ASN 67  ? B ASN 67  
11 1 Y 1 D GLN 68  ? B GLN 68  
12 1 Y 1 D TYR 69  ? B TYR 69  
13 1 Y 1 D GLN 70  ? B GLN 70  
14 1 Y 1 D GLY 71  ? B GLY 71  
15 1 Y 1 D SER 72  ? B SER 72  
16 1 Y 1 D ALA 73  ? B ALA 73  
17 1 Y 1 D HIS 74  ? B HIS 74  
18 1 Y 1 D VAL 75  ? B VAL 75  
19 1 Y 1 D SER 76  ? B SER 76  
20 1 Y 1 D VAL 77  ? B VAL 77  
21 1 Y 1 D LEU 78  ? B LEU 78  
22 1 Y 1 D ASP 79  ? B ASP 79  
23 1 Y 1 D SER 614 ? B SER 614 
24 1 Y 1 D THR 615 ? B THR 615 
25 1 Y 1 D GLY 616 ? B GLY 616 
26 1 Y 1 D ARG 617 ? B ARG 617 
27 1 Y 1 D PRO 618 ? B PRO 618 
28 1 Y 1 D SER 619 ? B SER 619 
29 1 Y 1 D VAL 620 ? B VAL 620 
30 1 Y 1 D ALA 621 ? B ALA 621 
31 1 Y 1 D LYS 622 ? B LYS 622 
32 1 Y 1 D THR 623 ? B THR 623 
33 1 Y 1 D ALA 624 ? B ALA 624 
34 1 Y 1 D THR 625 ? B THR 625 
35 1 Y 1 D ASP 626 ? B ASP 626 
36 1 Y 1 D PRO 627 ? B PRO 627 
37 1 Y 1 D VAL 628 ? B VAL 628 
38 1 Y 1 D THR 629 ? B THR 629 
39 1 Y 1 D LEU 630 ? B LEU 630 
40 1 Y 1 D LEU 631 ? B LEU 631 
41 1 Y 1 D ALA 632 ? B ALA 632 
42 1 Y 1 D ASP 633 ? B ASP 633 
43 1 Y 1 D LYS 634 ? B LYS 634 
44 1 Y 1 D ILE 635 ? B ILE 635 
45 1 Y 1 D SER 636 ? B SER 636 
46 1 Y 1 D LYS 637 ? B LYS 637 
47 1 Y 1 D ASN 638 ? B ASN 638 
48 1 Y 1 D THR 639 ? B THR 639 
49 1 Y 1 D LEU 640 ? B LEU 640 
50 1 Y 1 D VAL 641 ? B VAL 641 
51 1 Y 1 D VAL 642 ? B VAL 642 
52 1 Y 1 D GLU 643 ? B GLU 643 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FE  FE   FE N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
ZN  ZN   ZN N N 389 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-05-19 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8JFW 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Cryo-EM structure of RDGC/apo-CaM complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          7227 
_em_entity_assembly_naturalsource.organism             'Drosophila melanogaster' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Science Foundation (NSF, China)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8JFW 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLN A 1 4   ? 124.374 123.734 78.012  1.00 96.41  ? 4   GLN A N   1 
ATOM   2    C  CA  . GLN A 1 4   ? 123.510 122.796 77.305  1.00 96.41  ? 4   GLN A CA  1 
ATOM   3    C  C   . GLN A 1 4   ? 122.133 122.716 77.956  1.00 96.41  ? 4   GLN A C   1 
ATOM   4    O  O   . GLN A 1 4   ? 121.124 123.055 77.339  1.00 96.41  ? 4   GLN A O   1 
ATOM   5    C  CB  . GLN A 1 4   ? 124.150 121.408 77.258  1.00 96.41  ? 4   GLN A CB  1 
ATOM   6    C  CG  . GLN A 1 4   ? 123.376 120.384 76.438  1.00 96.41  ? 4   GLN A CG  1 
ATOM   7    C  CD  . GLN A 1 4   ? 122.978 120.902 75.069  1.00 96.41  ? 4   GLN A CD  1 
ATOM   8    O  OE1 . GLN A 1 4   ? 121.903 121.480 74.897  1.00 96.41  ? 4   GLN A OE1 1 
ATOM   9    N  NE2 . GLN A 1 4   ? 123.845 120.698 74.085  1.00 96.41  ? 4   GLN A NE2 1 
ATOM   10   N  N   . LEU A 1 5   ? 122.101 122.261 79.205  1.00 97.72  ? 5   LEU A N   1 
ATOM   11   C  CA  . LEU A 1 5   ? 120.845 122.151 79.930  1.00 97.72  ? 5   LEU A CA  1 
ATOM   12   C  C   . LEU A 1 5   ? 120.330 123.530 80.328  1.00 97.72  ? 5   LEU A C   1 
ATOM   13   O  O   . LEU A 1 5   ? 121.095 124.486 80.485  1.00 97.72  ? 5   LEU A O   1 
ATOM   14   C  CB  . LEU A 1 5   ? 121.020 121.278 81.172  1.00 97.72  ? 5   LEU A CB  1 
ATOM   15   N  N   . THR A 1 6   ? 119.014 123.625 80.489  1.00 94.32  ? 6   THR A N   1 
ATOM   16   C  CA  . THR A 1 6   ? 118.388 124.885 80.860  1.00 94.32  ? 6   THR A CA  1 
ATOM   17   C  C   . THR A 1 6   ? 118.751 125.260 82.294  1.00 94.32  ? 6   THR A C   1 
ATOM   18   O  O   . THR A 1 6   ? 119.111 124.408 83.111  1.00 94.32  ? 6   THR A O   1 
ATOM   19   C  CB  . THR A 1 6   ? 116.869 124.791 80.706  1.00 94.32  ? 6   THR A CB  1 
ATOM   20   O  OG1 . THR A 1 6   ? 116.554 123.945 79.593  1.00 94.32  ? 6   THR A OG1 1 
ATOM   21   C  CG2 . THR A 1 6   ? 116.266 126.167 80.461  1.00 94.32  ? 6   THR A CG2 1 
ATOM   22   N  N   . GLU A 1 7   ? 118.663 126.560 82.590  1.00 88.49  ? 7   GLU A N   1 
ATOM   23   C  CA  . GLU A 1 7   ? 119.016 127.051 83.919  1.00 88.49  ? 7   GLU A CA  1 
ATOM   24   C  C   . GLU A 1 7   ? 118.148 126.431 85.007  1.00 88.49  ? 7   GLU A C   1 
ATOM   25   O  O   . GLU A 1 7   ? 118.617 126.220 86.131  1.00 88.49  ? 7   GLU A O   1 
ATOM   26   C  CB  . GLU A 1 7   ? 118.902 128.576 83.960  1.00 88.49  ? 7   GLU A CB  1 
ATOM   27   N  N   . GLU A 1 8   ? 116.881 126.150 84.703  1.00 89.19  ? 8   GLU A N   1 
ATOM   28   C  CA  . GLU A 1 8   ? 116.028 125.468 85.670  1.00 89.19  ? 8   GLU A CA  1 
ATOM   29   C  C   . GLU A 1 8   ? 116.334 123.976 85.732  1.00 89.19  ? 8   GLU A C   1 
ATOM   30   O  O   . GLU A 1 8   ? 116.222 123.360 86.799  1.00 89.19  ? 8   GLU A O   1 
ATOM   31   C  CB  . GLU A 1 8   ? 114.557 125.698 85.324  1.00 89.19  ? 8   GLU A CB  1 
ATOM   32   N  N   . GLN A 1 9   ? 116.717 123.385 84.597  1.00 86.83  ? 9   GLN A N   1 
ATOM   33   C  CA  . GLN A 1 9   ? 116.943 121.945 84.543  1.00 86.83  ? 9   GLN A CA  1 
ATOM   34   C  C   . GLN A 1 9   ? 118.149 121.534 85.378  1.00 86.83  ? 9   GLN A C   1 
ATOM   35   O  O   . GLN A 1 9   ? 118.125 120.489 86.038  1.00 86.83  ? 9   GLN A O   1 
ATOM   36   C  CB  . GLN A 1 9   ? 117.120 121.495 83.093  1.00 86.83  ? 9   GLN A CB  1 
ATOM   37   C  CG  . GLN A 1 9   ? 115.836 121.497 82.280  1.00 86.83  ? 9   GLN A CG  1 
ATOM   38   C  CD  . GLN A 1 9   ? 116.069 121.144 80.824  1.00 86.83  ? 9   GLN A CD  1 
ATOM   39   O  OE1 . GLN A 1 9   ? 117.122 121.442 80.261  1.00 86.83  ? 9   GLN A OE1 1 
ATOM   40   N  NE2 . GLN A 1 9   ? 115.083 120.504 80.206  1.00 86.83  ? 9   GLN A NE2 1 
ATOM   41   N  N   . ILE A 1 10  ? 119.217 122.337 85.361  1.00 87.67  ? 10  ILE A N   1 
ATOM   42   C  CA  . ILE A 1 10  ? 120.429 121.965 86.082  1.00 87.67  ? 10  ILE A CA  1 
ATOM   43   C  C   . ILE A 1 10  ? 120.202 121.920 87.587  1.00 87.67  ? 10  ILE A C   1 
ATOM   44   O  O   . ILE A 1 10  ? 121.007 121.326 88.313  1.00 87.67  ? 10  ILE A O   1 
ATOM   45   C  CB  . ILE A 1 10  ? 121.586 122.921 85.741  1.00 87.67  ? 10  ILE A CB  1 
ATOM   46   C  CG1 . ILE A 1 10  ? 121.084 124.361 85.646  1.00 87.67  ? 10  ILE A CG1 1 
ATOM   47   C  CG2 . ILE A 1 10  ? 122.257 122.500 84.443  1.00 87.67  ? 10  ILE A CG2 1 
ATOM   48   C  CD1 . ILE A 1 10  ? 122.139 125.350 85.197  1.00 87.67  ? 10  ILE A CD1 1 
ATOM   49   N  N   . ALA A 1 11  ? 119.128 122.537 88.078  1.00 79.15  ? 11  ALA A N   1 
ATOM   50   C  CA  . ALA A 1 11  ? 118.771 122.453 89.488  1.00 79.15  ? 11  ALA A CA  1 
ATOM   51   C  C   . ALA A 1 11  ? 117.687 121.408 89.732  1.00 79.15  ? 11  ALA A C   1 
ATOM   52   O  O   . ALA A 1 11  ? 117.720 120.697 90.743  1.00 79.15  ? 11  ALA A O   1 
ATOM   53   C  CB  . ALA A 1 11  ? 118.315 123.822 89.999  1.00 79.15  ? 11  ALA A CB  1 
ATOM   54   N  N   . GLU A 1 12  ? 116.721 121.305 88.814  1.00 77.13  ? 12  GLU A N   1 
ATOM   55   C  CA  . GLU A 1 12  ? 115.658 120.318 88.968  1.00 77.13  ? 12  GLU A CA  1 
ATOM   56   C  C   . GLU A 1 12  ? 116.214 118.900 88.940  1.00 77.13  ? 12  GLU A C   1 
ATOM   57   O  O   . GLU A 1 12  ? 115.796 118.045 89.729  1.00 77.13  ? 12  GLU A O   1 
ATOM   58   C  CB  . GLU A 1 12  ? 114.607 120.504 87.875  1.00 77.13  ? 12  GLU A CB  1 
ATOM   59   C  CG  . GLU A 1 12  ? 113.463 119.508 87.939  1.00 77.13  ? 12  GLU A CG  1 
ATOM   60   C  CD  . GLU A 1 12  ? 112.339 119.851 86.983  1.00 77.13  ? 12  GLU A CD  1 
ATOM   61   O  OE1 . GLU A 1 12  ? 112.592 120.587 86.007  1.00 77.13  ? 12  GLU A OE1 1 
ATOM   62   O  OE2 . GLU A 1 12  ? 111.202 119.387 87.208  1.00 77.13  ? 12  GLU A OE2 1 
ATOM   63   N  N   . PHE A 1 13  ? 117.156 118.632 88.034  1.00 74.96  ? 13  PHE A N   1 
ATOM   64   C  CA  . PHE A 1 13  ? 117.759 117.306 87.958  1.00 74.96  ? 13  PHE A CA  1 
ATOM   65   C  C   . PHE A 1 13  ? 118.528 116.980 89.230  1.00 74.96  ? 13  PHE A C   1 
ATOM   66   O  O   . PHE A 1 13  ? 118.460 115.852 89.732  1.00 74.96  ? 13  PHE A O   1 
ATOM   67   C  CB  . PHE A 1 13  ? 118.681 117.219 86.741  1.00 74.96  ? 13  PHE A CB  1 
ATOM   68   C  CG  . PHE A 1 13  ? 117.955 117.086 85.430  1.00 74.96  ? 13  PHE A CG  1 
ATOM   69   C  CD1 . PHE A 1 13  ? 116.781 117.780 85.190  1.00 74.96  ? 13  PHE A CD1 1 
ATOM   70   C  CD2 . PHE A 1 13  ? 118.459 116.272 84.432  1.00 74.96  ? 13  PHE A CD2 1 
ATOM   71   C  CE1 . PHE A 1 13  ? 116.121 117.661 83.986  1.00 74.96  ? 13  PHE A CE1 1 
ATOM   72   C  CE2 . PHE A 1 13  ? 117.803 116.150 83.228  1.00 74.96  ? 13  PHE A CE2 1 
ATOM   73   C  CZ  . PHE A 1 13  ? 116.632 116.846 83.004  1.00 74.96  ? 13  PHE A CZ  1 
ATOM   74   N  N   . LYS A 1 14  ? 119.267 117.956 89.763  1.00 76.91  ? 14  LYS A N   1 
ATOM   75   C  CA  . LYS A 1 14  ? 120.003 117.736 91.004  1.00 76.91  ? 14  LYS A CA  1 
ATOM   76   C  C   . LYS A 1 14  ? 119.055 117.455 92.162  1.00 76.91  ? 14  LYS A C   1 
ATOM   77   O  O   . LYS A 1 14  ? 119.330 116.591 93.003  1.00 76.91  ? 14  LYS A O   1 
ATOM   78   C  CB  . LYS A 1 14  ? 120.887 118.944 91.313  1.00 76.91  ? 14  LYS A CB  1 
ATOM   79   N  N   . GLU A 1 15  ? 117.937 118.181 92.227  1.00 71.64  ? 15  GLU A N   1 
ATOM   80   C  CA  . GLU A 1 15  ? 116.959 117.928 93.281  1.00 71.64  ? 15  GLU A CA  1 
ATOM   81   C  C   . GLU A 1 15  ? 116.336 116.545 93.130  1.00 71.64  ? 15  GLU A C   1 
ATOM   82   O  O   . GLU A 1 15  ? 116.092 115.849 94.122  1.00 71.64  ? 15  GLU A O   1 
ATOM   83   C  CB  . GLU A 1 15  ? 115.884 119.015 93.278  1.00 71.64  ? 15  GLU A CB  1 
ATOM   84   C  CG  . GLU A 1 15  ? 116.286 120.264 94.045  1.00 71.64  ? 15  GLU A CG  1 
ATOM   85   C  CD  . GLU A 1 15  ? 115.133 121.224 94.246  1.00 71.64  ? 15  GLU A CD  1 
ATOM   86   O  OE1 . GLU A 1 15  ? 114.007 120.754 94.512  1.00 71.64  ? 15  GLU A OE1 1 
ATOM   87   O  OE2 . GLU A 1 15  ? 115.355 122.449 94.143  1.00 71.64  ? 15  GLU A OE2 1 
ATOM   88   N  N   . ALA A 1 16  ? 116.069 116.129 91.890  1.00 65.66  ? 16  ALA A N   1 
ATOM   89   C  CA  . ALA A 1 16  ? 115.533 114.790 91.664  1.00 65.66  ? 16  ALA A CA  1 
ATOM   90   C  C   . ALA A 1 16  ? 116.606 113.722 91.831  1.00 65.66  ? 16  ALA A C   1 
ATOM   91   O  O   . ALA A 1 16  ? 116.286 112.538 91.985  1.00 65.66  ? 16  ALA A O   1 
ATOM   92   C  CB  . ALA A 1 16  ? 114.905 114.701 90.274  1.00 65.66  ? 16  ALA A CB  1 
ATOM   93   N  N   . PHE A 1 17  ? 117.880 114.117 91.796  1.00 74.75  ? 17  PHE A N   1 
ATOM   94   C  CA  . PHE A 1 17  ? 118.964 113.157 91.978  1.00 74.75  ? 17  PHE A CA  1 
ATOM   95   C  C   . PHE A 1 17  ? 119.102 112.741 93.437  1.00 74.75  ? 17  PHE A C   1 
ATOM   96   O  O   . PHE A 1 17  ? 119.389 111.575 93.731  1.00 74.75  ? 17  PHE A O   1 
ATOM   97   C  CB  . PHE A 1 17  ? 120.275 113.752 91.466  1.00 74.75  ? 17  PHE A CB  1 
ATOM   98   C  CG  . PHE A 1 17  ? 121.253 112.730 90.969  1.00 74.75  ? 17  PHE A CG  1 
ATOM   99   C  CD1 . PHE A 1 17  ? 122.028 112.007 91.859  1.00 74.75  ? 17  PHE A CD1 1 
ATOM   100  C  CD2 . PHE A 1 17  ? 121.402 112.493 89.615  1.00 74.75  ? 17  PHE A CD2 1 
ATOM   101  C  CE1 . PHE A 1 17  ? 122.932 111.069 91.408  1.00 74.75  ? 17  PHE A CE1 1 
ATOM   102  C  CE2 . PHE A 1 17  ? 122.304 111.554 89.158  1.00 74.75  ? 17  PHE A CE2 1 
ATOM   103  C  CZ  . PHE A 1 17  ? 123.070 110.841 90.056  1.00 74.75  ? 17  PHE A CZ  1 
ATOM   104  N  N   . SER A 1 18  ? 118.903 113.679 94.366  1.00 66.66  ? 18  SER A N   1 
ATOM   105  C  CA  . SER A 1 18  ? 119.141 113.401 95.777  1.00 66.66  ? 18  SER A CA  1 
ATOM   106  C  C   . SER A 1 18  ? 118.106 112.459 96.377  1.00 66.66  ? 18  SER A C   1 
ATOM   107  O  O   . SER A 1 18  ? 118.336 111.923 97.465  1.00 66.66  ? 18  SER A O   1 
ATOM   108  C  CB  . SER A 1 18  ? 119.171 114.707 96.572  1.00 66.66  ? 18  SER A CB  1 
ATOM   109  O  OG  . SER A 1 18  ? 117.862 115.212 96.769  1.00 66.66  ? 18  SER A OG  1 
ATOM   110  N  N   . LEU A 1 19  ? 116.976 112.247 95.701  1.00 57.31  ? 19  LEU A N   1 
ATOM   111  C  CA  . LEU A 1 19  ? 115.951 111.353 96.223  1.00 57.31  ? 19  LEU A CA  1 
ATOM   112  C  C   . LEU A 1 19  ? 116.341 109.885 96.125  1.00 57.31  ? 19  LEU A C   1 
ATOM   113  O  O   . LEU A 1 19  ? 115.683 109.046 96.750  1.00 57.31  ? 19  LEU A O   1 
ATOM   114  C  CB  . LEU A 1 19  ? 114.629 111.584 95.489  1.00 57.31  ? 19  LEU A CB  1 
ATOM   115  C  CG  . LEU A 1 19  ? 113.645 112.549 96.151  1.00 57.31  ? 19  LEU A CG  1 
ATOM   116  C  CD1 . LEU A 1 19  ? 114.110 113.984 95.990  1.00 57.31  ? 19  LEU A CD1 1 
ATOM   117  C  CD2 . LEU A 1 19  ? 112.254 112.371 95.572  1.00 57.31  ? 19  LEU A CD2 1 
ATOM   118  N  N   . PHE A 1 20  ? 117.386 109.554 95.365  1.00 68.99  ? 20  PHE A N   1 
ATOM   119  C  CA  . PHE A 1 20  ? 117.814 108.174 95.191  1.00 68.99  ? 20  PHE A CA  1 
ATOM   120  C  C   . PHE A 1 20  ? 119.203 107.892 95.747  1.00 68.99  ? 20  PHE A C   1 
ATOM   121  O  O   . PHE A 1 20  ? 119.614 106.727 95.771  1.00 68.99  ? 20  PHE A O   1 
ATOM   122  C  CB  . PHE A 1 20  ? 117.784 107.791 93.703  1.00 68.99  ? 20  PHE A CB  1 
ATOM   123  C  CG  . PHE A 1 20  ? 116.401 107.725 93.117  1.00 68.99  ? 20  PHE A CG  1 
ATOM   124  C  CD1 . PHE A 1 20  ? 115.712 108.882 92.795  1.00 68.99  ? 20  PHE A CD1 1 
ATOM   125  C  CD2 . PHE A 1 20  ? 115.792 106.504 92.882  1.00 68.99  ? 20  PHE A CD2 1 
ATOM   126  C  CE1 . PHE A 1 20  ? 114.444 108.823 92.253  1.00 68.99  ? 20  PHE A CE1 1 
ATOM   127  C  CE2 . PHE A 1 20  ? 114.523 106.440 92.341  1.00 68.99  ? 20  PHE A CE2 1 
ATOM   128  C  CZ  . PHE A 1 20  ? 113.849 107.601 92.026  1.00 68.99  ? 20  PHE A CZ  1 
ATOM   129  N  N   . ASP A 1 21  ? 119.932 108.914 96.190  1.00 93.80  ? 21  ASP A N   1 
ATOM   130  C  CA  . ASP A 1 21  ? 121.288 108.730 96.698  1.00 93.80  ? 21  ASP A CA  1 
ATOM   131  C  C   . ASP A 1 21  ? 121.218 108.220 98.133  1.00 93.80  ? 21  ASP A C   1 
ATOM   132  O  O   . ASP A 1 21  ? 120.618 108.862 99.001  1.00 93.80  ? 21  ASP A O   1 
ATOM   133  C  CB  . ASP A 1 21  ? 122.069 110.038 96.614  1.00 93.80  ? 21  ASP A CB  1 
ATOM   134  C  CG  . ASP A 1 21  ? 123.565 109.835 96.758  1.00 93.80  ? 21  ASP A CG  1 
ATOM   135  O  OD1 . ASP A 1 21  ? 123.991 108.695 97.037  1.00 93.80  ? 21  ASP A OD1 1 
ATOM   136  O  OD2 . ASP A 1 21  ? 124.317 110.817 96.589  1.00 93.80  ? 21  ASP A OD2 1 
ATOM   137  N  N   . LYS A 1 22  ? 121.835 107.063 98.383  1.00 97.95  ? 22  LYS A N   1 
ATOM   138  C  CA  . LYS A 1 22  ? 121.820 106.490 99.724  1.00 97.95  ? 22  LYS A CA  1 
ATOM   139  C  C   . LYS A 1 22  ? 122.793 107.199 100.658 1.00 97.95  ? 22  LYS A C   1 
ATOM   140  O  O   . LYS A 1 22  ? 122.488 107.385 101.841 1.00 97.95  ? 22  LYS A O   1 
ATOM   141  C  CB  . LYS A 1 22  ? 122.142 104.997 99.660  1.00 97.95  ? 22  LYS A CB  1 
ATOM   142  N  N   . ASP A 1 23  ? 123.960 107.599 100.153 1.00 106.72 ? 23  ASP A N   1 
ATOM   143  C  CA  . ASP A 1 23  ? 124.991 108.209 100.980 1.00 106.72 ? 23  ASP A CA  1 
ATOM   144  C  C   . ASP A 1 23  ? 125.085 109.720 100.823 1.00 106.72 ? 23  ASP A C   1 
ATOM   145  O  O   . ASP A 1 23  ? 125.832 110.357 101.575 1.00 106.72 ? 23  ASP A O   1 
ATOM   146  C  CB  . ASP A 1 23  ? 126.358 107.582 100.673 1.00 106.72 ? 23  ASP A CB  1 
ATOM   147  C  CG  . ASP A 1 23  ? 126.393 106.094 100.958 1.00 106.72 ? 23  ASP A CG  1 
ATOM   148  O  OD1 . ASP A 1 23  ? 125.374 105.557 101.439 1.00 106.72 ? 23  ASP A OD1 1 
ATOM   149  O  OD2 . ASP A 1 23  ? 127.440 105.463 100.702 1.00 106.72 ? 23  ASP A OD2 1 
ATOM   150  N  N   . GLY A 1 24  ? 124.361 110.311 99.877  1.00 106.82 ? 24  GLY A N   1 
ATOM   151  C  CA  . GLY A 1 24  ? 124.412 111.745 99.684  1.00 106.82 ? 24  GLY A CA  1 
ATOM   152  C  C   . GLY A 1 24  ? 125.665 112.260 99.015  1.00 106.82 ? 24  GLY A C   1 
ATOM   153  O  O   . GLY A 1 24  ? 125.903 113.473 99.035  1.00 106.82 ? 24  GLY A O   1 
ATOM   154  N  N   . ASP A 1 25  ? 126.471 111.384 98.422  1.00 104.28 ? 25  ASP A N   1 
ATOM   155  C  CA  . ASP A 1 25  ? 127.719 111.776 97.782  1.00 104.28 ? 25  ASP A CA  1 
ATOM   156  C  C   . ASP A 1 25  ? 127.548 112.138 96.312  1.00 104.28 ? 25  ASP A C   1 
ATOM   157  O  O   . ASP A 1 25  ? 128.546 112.400 95.634  1.00 104.28 ? 25  ASP A O   1 
ATOM   158  C  CB  . ASP A 1 25  ? 128.754 110.653 97.917  1.00 104.28 ? 25  ASP A CB  1 
ATOM   159  C  CG  . ASP A 1 25  ? 128.242 109.323 97.400  1.00 104.28 ? 25  ASP A CG  1 
ATOM   160  O  OD1 . ASP A 1 25  ? 127.025 109.212 97.140  1.00 104.28 ? 25  ASP A OD1 1 
ATOM   161  O  OD2 . ASP A 1 25  ? 129.056 108.388 97.255  1.00 104.28 ? 25  ASP A OD2 1 
ATOM   162  N  N   . GLY A 1 26  ? 126.318 112.157 95.806  1.00 97.42  ? 26  GLY A N   1 
ATOM   163  C  CA  . GLY A 1 26  ? 126.082 112.446 94.407  1.00 97.42  ? 26  GLY A CA  1 
ATOM   164  C  C   . GLY A 1 26  ? 126.237 111.267 93.476  1.00 97.42  ? 26  GLY A C   1 
ATOM   165  O  O   . GLY A 1 26  ? 126.126 111.443 92.257  1.00 97.42  ? 26  GLY A O   1 
ATOM   166  N  N   . THR A 1 27  ? 126.492 110.074 94.006  1.00 102.72 ? 27  THR A N   1 
ATOM   167  C  CA  . THR A 1 27  ? 126.640 108.866 93.209  1.00 102.72 ? 27  THR A CA  1 
ATOM   168  C  C   . THR A 1 27  ? 125.591 107.846 93.630  1.00 102.72 ? 27  THR A C   1 
ATOM   169  O  O   . THR A 1 27  ? 125.402 107.594 94.824  1.00 102.72 ? 27  THR A O   1 
ATOM   170  C  CB  . THR A 1 27  ? 128.040 108.263 93.365  1.00 102.72 ? 27  THR A CB  1 
ATOM   171  O  OG1 . THR A 1 27  ? 128.146 107.621 94.641  1.00 102.72 ? 27  THR A OG1 1 
ATOM   172  C  CG2 . THR A 1 27  ? 129.103 109.346 93.258  1.00 102.72 ? 27  THR A CG2 1 
ATOM   173  N  N   . ILE A 1 28  ? 124.915 107.258 92.644  1.00 92.60  ? 28  ILE A N   1 
ATOM   174  C  CA  . ILE A 1 28  ? 123.871 106.273 92.888  1.00 92.60  ? 28  ILE A CA  1 
ATOM   175  C  C   . ILE A 1 28  ? 124.230 104.983 92.166  1.00 92.60  ? 28  ILE A C   1 
ATOM   176  O  O   . ILE A 1 28  ? 125.058 104.961 91.253  1.00 92.60  ? 28  ILE A O   1 
ATOM   177  C  CB  . ILE A 1 28  ? 122.479 106.763 92.437  1.00 92.60  ? 28  ILE A CB  1 
ATOM   178  C  CG1 . ILE A 1 28  ? 122.424 106.878 90.911  1.00 92.60  ? 28  ILE A CG1 1 
ATOM   179  C  CG2 . ILE A 1 28  ? 122.135 108.084 93.107  1.00 92.60  ? 28  ILE A CG2 1 
ATOM   180  C  CD1 . ILE A 1 28  ? 121.323 107.779 90.398  1.00 92.60  ? 28  ILE A CD1 1 
ATOM   181  N  N   . THR A 1 29  ? 123.594 103.898 92.596  1.00 99.52  ? 29  THR A N   1 
ATOM   182  C  CA  . THR A 1 29  ? 123.793 102.611 91.949  1.00 99.52  ? 29  THR A CA  1 
ATOM   183  C  C   . THR A 1 29  ? 123.236 102.636 90.530  1.00 99.52  ? 29  THR A C   1 
ATOM   184  O  O   . THR A 1 29  ? 122.244 103.309 90.236  1.00 99.52  ? 29  THR A O   1 
ATOM   185  C  CB  . THR A 1 29  ? 123.132 101.493 92.756  1.00 99.52  ? 29  THR A CB  1 
ATOM   186  O  OG1 . THR A 1 29  ? 123.228 100.258 92.035  1.00 99.52  ? 29  THR A OG1 1 
ATOM   187  C  CG2 . THR A 1 29  ? 121.671 101.814 93.022  1.00 99.52  ? 29  THR A CG2 1 
ATOM   188  N  N   . THR A 1 30  ? 123.898 101.895 89.641  1.00 105.78 ? 30  THR A N   1 
ATOM   189  C  CA  . THR A 1 30  ? 123.521 101.901 88.233  1.00 105.78 ? 30  THR A CA  1 
ATOM   190  C  C   . THR A 1 30  ? 122.209 101.174 87.970  1.00 105.78 ? 30  THR A C   1 
ATOM   191  O  O   . THR A 1 30  ? 121.586 101.409 86.928  1.00 105.78 ? 30  THR A O   1 
ATOM   192  C  CB  . THR A 1 30  ? 124.633 101.274 87.393  1.00 105.78 ? 30  THR A CB  1 
ATOM   193  O  OG1 . THR A 1 30  ? 125.118 100.092 88.044  1.00 105.78 ? 30  THR A OG1 1 
ATOM   194  C  CG2 . THR A 1 30  ? 125.778 102.256 87.211  1.00 105.78 ? 30  THR A CG2 1 
ATOM   195  N  N   . LYS A 1 31  ? 121.776 100.301 88.882  1.00 109.18 ? 31  LYS A N   1 
ATOM   196  C  CA  . LYS A 1 31  ? 120.549 99.543  88.664  1.00 109.18 ? 31  LYS A CA  1 
ATOM   197  C  C   . LYS A 1 31  ? 119.307 100.424 88.666  1.00 109.18 ? 31  LYS A C   1 
ATOM   198  O  O   . LYS A 1 31  ? 118.274 100.016 88.124  1.00 109.18 ? 31  LYS A O   1 
ATOM   199  C  CB  . LYS A 1 31  ? 120.413 98.450  89.724  1.00 109.18 ? 31  LYS A CB  1 
ATOM   200  C  CG  . LYS A 1 31  ? 121.433 97.332  89.589  1.00 109.18 ? 31  LYS A CG  1 
ATOM   201  C  CD  . LYS A 1 31  ? 121.268 96.591  88.272  1.00 109.18 ? 31  LYS A CD  1 
ATOM   202  C  CE  . LYS A 1 31  ? 121.914 95.216  88.327  1.00 109.18 ? 31  LYS A CE  1 
ATOM   203  N  NZ  . LYS A 1 31  ? 123.399 95.304  88.372  1.00 109.18 ? 31  LYS A NZ  1 
ATOM   204  N  N   . GLU A 1 32  ? 119.379 101.614 89.257  1.00 98.23  ? 32  GLU A N   1 
ATOM   205  C  CA  . GLU A 1 32  ? 118.245 102.526 89.312  1.00 98.23  ? 32  GLU A CA  1 
ATOM   206  C  C   . GLU A 1 32  ? 118.263 103.570 88.205  1.00 98.23  ? 32  GLU A C   1 
ATOM   207  O  O   . GLU A 1 32  ? 117.439 104.490 88.233  1.00 98.23  ? 32  GLU A O   1 
ATOM   208  C  CB  . GLU A 1 32  ? 118.193 103.224 90.675  1.00 98.23  ? 32  GLU A CB  1 
ATOM   209  C  CG  . GLU A 1 32  ? 118.268 102.279 91.863  1.00 98.23  ? 32  GLU A CG  1 
ATOM   210  C  CD  . GLU A 1 32  ? 116.934 101.634 92.191  1.00 98.23  ? 32  GLU A CD  1 
ATOM   211  O  OE1 . GLU A 1 32  ? 116.856 100.920 93.213  1.00 98.23  ? 32  GLU A OE1 1 
ATOM   212  O  OE2 . GLU A 1 32  ? 115.963 101.843 91.435  1.00 98.23  ? 32  GLU A OE2 1 
ATOM   213  N  N   . LEU A 1 33  ? 119.177 103.454 87.238  1.00 88.06  ? 33  LEU A N   1 
ATOM   214  C  CA  . LEU A 1 33  ? 119.231 104.424 86.148  1.00 88.06  ? 33  LEU A CA  1 
ATOM   215  C  C   . LEU A 1 33  ? 117.935 104.426 85.347  1.00 88.06  ? 33  LEU A C   1 
ATOM   216  O  O   . LEU A 1 33  ? 117.434 105.490 84.959  1.00 88.06  ? 33  LEU A O   1 
ATOM   217  C  CB  . LEU A 1 33  ? 120.423 104.128 85.239  1.00 88.06  ? 33  LEU A CB  1 
ATOM   218  C  CG  . LEU A 1 33  ? 121.040 105.332 84.526  1.00 88.06  ? 33  LEU A CG  1 
ATOM   219  C  CD1 . LEU A 1 33  ? 121.408 106.417 85.525  1.00 88.06  ? 33  LEU A CD1 1 
ATOM   220  C  CD2 . LEU A 1 33  ? 122.254 104.912 83.713  1.00 88.06  ? 33  LEU A CD2 1 
ATOM   221  N  N   . GLY A 1 34  ? 117.370 103.244 85.101  1.00 88.64  ? 34  GLY A N   1 
ATOM   222  C  CA  . GLY A 1 34  ? 116.119 103.133 84.376  1.00 88.64  ? 34  GLY A CA  1 
ATOM   223  C  C   . GLY A 1 34  ? 114.919 103.698 85.104  1.00 88.64  ? 34  GLY A C   1 
ATOM   224  O  O   . GLY A 1 34  ? 113.841 103.786 84.506  1.00 88.64  ? 34  GLY A O   1 
ATOM   225  N  N   . THR A 1 35  ? 115.071 104.065 86.375  1.00 79.69  ? 35  THR A N   1 
ATOM   226  C  CA  . THR A 1 35  ? 114.003 104.726 87.111  1.00 79.69  ? 35  THR A CA  1 
ATOM   227  C  C   . THR A 1 35  ? 114.176 106.241 87.109  1.00 79.69  ? 35  THR A C   1 
ATOM   228  O  O   . THR A 1 35  ? 113.229 106.977 86.811  1.00 79.69  ? 35  THR A O   1 
ATOM   229  C  CB  . THR A 1 35  ? 113.948 104.201 88.549  1.00 79.69  ? 35  THR A CB  1 
ATOM   230  O  OG1 . THR A 1 35  ? 114.041 102.771 88.541  1.00 79.69  ? 35  THR A OG1 1 
ATOM   231  C  CG2 . THR A 1 35  ? 112.646 104.613 89.215  1.00 79.69  ? 35  THR A CG2 1 
ATOM   232  N  N   . VAL A 1 36  ? 115.380 106.719 87.432  1.00 75.21  ? 36  VAL A N   1 
ATOM   233  C  CA  . VAL A 1 36  ? 115.624 108.158 87.451  1.00 75.21  ? 36  VAL A CA  1 
ATOM   234  C  C   . VAL A 1 36  ? 115.492 108.744 86.052  1.00 75.21  ? 36  VAL A C   1 
ATOM   235  O  O   . VAL A 1 36  ? 114.896 109.812 85.869  1.00 75.21  ? 36  VAL A O   1 
ATOM   236  C  CB  . VAL A 1 36  ? 116.999 108.469 88.070  1.00 75.21  ? 36  VAL A CB  1 
ATOM   237  C  CG1 . VAL A 1 36  ? 116.944 108.320 89.577  1.00 75.21  ? 36  VAL A CG1 1 
ATOM   238  C  CG2 . VAL A 1 36  ? 118.070 107.569 87.487  1.00 75.21  ? 36  VAL A CG2 1 
ATOM   239  N  N   . MET A 1 37  ? 116.042 108.065 85.041  1.00 84.98  ? 37  MET A N   1 
ATOM   240  C  CA  . MET A 1 37  ? 115.954 108.591 83.684  1.00 84.98  ? 37  MET A CA  1 
ATOM   241  C  C   . MET A 1 37  ? 114.523 108.551 83.160  1.00 84.98  ? 37  MET A C   1 
ATOM   242  O  O   . MET A 1 37  ? 114.106 109.457 82.430  1.00 84.98  ? 37  MET A O   1 
ATOM   243  C  CB  . MET A 1 37  ? 116.891 107.818 82.758  1.00 84.98  ? 37  MET A CB  1 
ATOM   244  C  CG  . MET A 1 37  ? 118.040 108.656 82.220  1.00 84.98  ? 37  MET A CG  1 
ATOM   245  S  SD  . MET A 1 37  ? 118.866 107.925 80.795  1.00 84.98  ? 37  MET A SD  1 
ATOM   246  C  CE  . MET A 1 37  ? 117.516 107.859 79.624  1.00 84.98  ? 37  MET A CE  1 
ATOM   247  N  N   . ARG A 1 38  ? 113.761 107.514 83.518  1.00 79.63  ? 38  ARG A N   1 
ATOM   248  C  CA  . ARG A 1 38  ? 112.360 107.448 83.115  1.00 79.63  ? 38  ARG A CA  1 
ATOM   249  C  C   . ARG A 1 38  ? 111.533 108.538 83.786  1.00 79.63  ? 38  ARG A C   1 
ATOM   250  O  O   . ARG A 1 38  ? 110.630 109.108 83.164  1.00 79.63  ? 38  ARG A O   1 
ATOM   251  C  CB  . ARG A 1 38  ? 111.781 106.071 83.440  1.00 79.63  ? 38  ARG A CB  1 
ATOM   252  C  CG  . ARG A 1 38  ? 111.587 105.162 82.239  1.00 79.63  ? 38  ARG A CG  1 
ATOM   253  C  CD  . ARG A 1 38  ? 112.914 104.709 81.664  1.00 79.63  ? 38  ARG A CD  1 
ATOM   254  N  NE  . ARG A 1 38  ? 112.783 103.484 80.885  1.00 79.63  ? 38  ARG A NE  1 
ATOM   255  C  CZ  . ARG A 1 38  ? 112.726 102.267 81.409  1.00 79.63  ? 38  ARG A CZ  1 
ATOM   256  N  NH1 . ARG A 1 38  ? 112.784 102.074 82.716  1.00 79.63  ? 38  ARG A NH1 1 
ATOM   257  N  NH2 . ARG A 1 38  ? 112.608 101.218 80.600  1.00 79.63  ? 38  ARG A NH2 1 
ATOM   258  N  N   . SER A 1 39  ? 111.823 108.837 85.055  1.00 73.19  ? 39  SER A N   1 
ATOM   259  C  CA  . SER A 1 39  ? 110.987 109.760 85.815  1.00 73.19  ? 39  SER A CA  1 
ATOM   260  C  C   . SER A 1 39  ? 111.006 111.177 85.256  1.00 73.19  ? 39  SER A C   1 
ATOM   261  O  O   . SER A 1 39  ? 110.102 111.961 85.564  1.00 73.19  ? 39  SER A O   1 
ATOM   262  C  CB  . SER A 1 39  ? 111.426 109.779 87.279  1.00 73.19  ? 39  SER A CB  1 
ATOM   263  O  OG  . SER A 1 39  ? 112.835 109.861 87.383  1.00 73.19  ? 39  SER A OG  1 
ATOM   264  N  N   . LEU A 1 40  ? 112.008 111.528 84.447  1.00 73.32  ? 40  LEU A N   1 
ATOM   265  C  CA  . LEU A 1 40  ? 112.113 112.866 83.876  1.00 73.32  ? 40  LEU A CA  1 
ATOM   266  C  C   . LEU A 1 40  ? 111.604 112.941 82.440  1.00 73.32  ? 40  LEU A C   1 
ATOM   267  O  O   . LEU A 1 40  ? 112.124 113.734 81.644  1.00 73.32  ? 40  LEU A O   1 
ATOM   268  C  CB  . LEU A 1 40  ? 113.557 113.365 83.958  1.00 73.32  ? 40  LEU A CB  1 
ATOM   269  C  CG  . LEU A 1 40  ? 114.010 113.975 85.289  1.00 73.32  ? 40  LEU A CG  1 
ATOM   270  C  CD1 . LEU A 1 40  ? 112.960 114.941 85.818  1.00 73.32  ? 40  LEU A CD1 1 
ATOM   271  C  CD2 . LEU A 1 40  ? 114.327 112.909 86.323  1.00 73.32  ? 40  LEU A CD2 1 
ATOM   272  N  N   . GLY A 1 41  ? 110.600 112.139 82.087  1.00 78.19  ? 41  GLY A N   1 
ATOM   273  C  CA  . GLY A 1 41  ? 109.955 112.235 80.796  1.00 78.19  ? 41  GLY A CA  1 
ATOM   274  C  C   . GLY A 1 41  ? 110.538 111.370 79.699  1.00 78.19  ? 41  GLY A C   1 
ATOM   275  O  O   . GLY A 1 41  ? 109.977 111.341 78.596  1.00 78.19  ? 41  GLY A O   1 
ATOM   276  N  N   . GLN A 1 42  ? 111.638 110.670 79.953  1.00 86.19  ? 42  GLN A N   1 
ATOM   277  C  CA  . GLN A 1 42  ? 112.224 109.818 78.931  1.00 86.19  ? 42  GLN A CA  1 
ATOM   278  C  C   . GLN A 1 42  ? 111.669 108.400 79.028  1.00 86.19  ? 42  GLN A C   1 
ATOM   279  O  O   . GLN A 1 42  ? 111.278 107.928 80.099  1.00 86.19  ? 42  GLN A O   1 
ATOM   280  C  CB  . GLN A 1 42  ? 113.746 109.796 79.057  1.00 86.19  ? 42  GLN A CB  1 
ATOM   281  C  CG  . GLN A 1 42  ? 114.360 111.165 79.248  1.00 86.19  ? 42  GLN A CG  1 
ATOM   282  C  CD  . GLN A 1 42  ? 113.802 112.195 78.286  1.00 86.19  ? 42  GLN A CD  1 
ATOM   283  O  OE1 . GLN A 1 42  ? 113.971 112.083 77.072  1.00 86.19  ? 42  GLN A OE1 1 
ATOM   284  N  NE2 . GLN A 1 42  ? 113.129 113.205 78.825  1.00 86.19  ? 42  GLN A NE2 1 
ATOM   285  N  N   . ASN A 1 43  ? 111.631 107.718 77.880  1.00 86.99  ? 43  ASN A N   1 
ATOM   286  C  CA  . ASN A 1 43  ? 111.143 106.339 77.812  1.00 86.99  ? 43  ASN A CA  1 
ATOM   287  C  C   . ASN A 1 43  ? 112.064 105.452 76.974  1.00 86.99  ? 43  ASN A C   1 
ATOM   288  O  O   . ASN A 1 43  ? 111.700 105.012 75.883  1.00 86.99  ? 43  ASN A O   1 
ATOM   289  C  CB  . ASN A 1 43  ? 109.720 106.317 77.263  1.00 86.99  ? 43  ASN A CB  1 
ATOM   290  C  CG  . ASN A 1 43  ? 109.562 107.173 76.022  1.00 86.99  ? 43  ASN A CG  1 
ATOM   291  O  OD1 . ASN A 1 43  ? 110.412 108.011 75.721  1.00 86.99  ? 43  ASN A OD1 1 
ATOM   292  N  ND2 . ASN A 1 43  ? 108.470 106.967 75.295  1.00 86.99  ? 43  ASN A ND2 1 
ATOM   293  N  N   . PRO A 1 44  ? 113.273 105.167 77.457  1.00 88.84  ? 44  PRO A N   1 
ATOM   294  C  CA  . PRO A 1 44  ? 114.122 104.193 76.765  1.00 88.84  ? 44  PRO A CA  1 
ATOM   295  C  C   . PRO A 1 44  ? 113.875 102.781 77.272  1.00 88.84  ? 44  PRO A C   1 
ATOM   296  O  O   . PRO A 1 44  ? 113.460 102.567 78.413  1.00 88.84  ? 44  PRO A O   1 
ATOM   297  C  CB  . PRO A 1 44  ? 115.537 104.663 77.108  1.00 88.84  ? 44  PRO A CB  1 
ATOM   298  C  CG  . PRO A 1 44  ? 115.382 105.205 78.483  1.00 88.84  ? 44  PRO A CG  1 
ATOM   299  C  CD  . PRO A 1 44  ? 114.019 105.863 78.521  1.00 88.84  ? 44  PRO A CD  1 
ATOM   300  N  N   . THR A 1 45  ? 114.140 101.809 76.403  1.00 103.90 ? 45  THR A N   1 
ATOM   301  C  CA  . THR A 1 45  ? 114.028 100.410 76.783  1.00 103.90 ? 45  THR A CA  1 
ATOM   302  C  C   . THR A 1 45  ? 115.300 99.945  77.487  1.00 103.90 ? 45  THR A C   1 
ATOM   303  O  O   . THR A 1 45  ? 116.311 100.652 77.539  1.00 103.90 ? 45  THR A O   1 
ATOM   304  C  CB  . THR A 1 45  ? 113.755 99.533  75.562  1.00 103.90 ? 45  THR A CB  1 
ATOM   305  O  OG1 . THR A 1 45  ? 113.582 98.173  75.980  1.00 103.90 ? 45  THR A OG1 1 
ATOM   306  C  CG2 . THR A 1 45  ? 114.915 99.611  74.583  1.00 103.90 ? 45  THR A CG2 1 
ATOM   307  N  N   . GLU A 1 46  ? 115.243 98.729  78.037  1.00 116.51 ? 46  GLU A N   1 
ATOM   308  C  CA  . GLU A 1 46  ? 116.400 98.191  78.742  1.00 116.51 ? 46  GLU A CA  1 
ATOM   309  C  C   . GLU A 1 46  ? 117.559 97.918  77.792  1.00 116.51 ? 46  GLU A C   1 
ATOM   310  O  O   . GLU A 1 46  ? 118.719 97.909  78.216  1.00 116.51 ? 46  GLU A O   1 
ATOM   311  C  CB  . GLU A 1 46  ? 116.010 96.923  79.509  1.00 116.51 ? 46  GLU A CB  1 
ATOM   312  C  CG  . GLU A 1 46  ? 116.441 95.612  78.866  1.00 116.51 ? 46  GLU A CG  1 
ATOM   313  C  CD  . GLU A 1 46  ? 115.675 95.301  77.596  1.00 116.51 ? 46  GLU A CD  1 
ATOM   314  O  OE1 . GLU A 1 46  ? 116.109 94.399  76.849  1.00 116.51 ? 46  GLU A OE1 1 
ATOM   315  O  OE2 . GLU A 1 46  ? 114.640 95.954  77.349  1.00 116.51 ? 46  GLU A OE2 1 
ATOM   316  N  N   . ALA A 1 47  ? 117.271 97.692  76.507  1.00 108.89 ? 47  ALA A N   1 
ATOM   317  C  CA  . ALA A 1 47  ? 118.343 97.598  75.521  1.00 108.89 ? 47  ALA A CA  1 
ATOM   318  C  C   . ALA A 1 47  ? 119.059 98.934  75.369  1.00 108.89 ? 47  ALA A C   1 
ATOM   319  O  O   . ALA A 1 47  ? 120.295 98.983  75.304  1.00 108.89 ? 47  ALA A O   1 
ATOM   320  C  CB  . ALA A 1 47  ? 117.786 97.128  74.178  1.00 108.89 ? 47  ALA A CB  1 
ATOM   321  N  N   . GLU A 1 48  ? 118.297 100.029 75.317  1.00 106.07 ? 48  GLU A N   1 
ATOM   322  C  CA  . GLU A 1 48  ? 118.906 101.354 75.300  1.00 106.07 ? 48  GLU A CA  1 
ATOM   323  C  C   . GLU A 1 48  ? 119.679 101.614 76.584  1.00 106.07 ? 48  GLU A C   1 
ATOM   324  O  O   . GLU A 1 48  ? 120.746 102.233 76.559  1.00 106.07 ? 48  GLU A O   1 
ATOM   325  C  CB  . GLU A 1 48  ? 117.836 102.425 75.089  1.00 106.07 ? 48  GLU A CB  1 
ATOM   326  C  CG  . GLU A 1 48  ? 117.158 102.368 73.731  1.00 106.07 ? 48  GLU A CG  1 
ATOM   327  C  CD  . GLU A 1 48  ? 115.981 103.317 73.628  1.00 106.07 ? 48  GLU A CD  1 
ATOM   328  O  OE1 . GLU A 1 48  ? 116.201 104.546 73.663  1.00 106.07 ? 48  GLU A OE1 1 
ATOM   329  O  OE2 . GLU A 1 48  ? 114.835 102.833 73.513  1.00 106.07 ? 48  GLU A OE2 1 
ATOM   330  N  N   . LEU A 1 49  ? 119.156 101.143 77.719  1.00 110.48 ? 49  LEU A N   1 
ATOM   331  C  CA  . LEU A 1 49  ? 119.872 101.294 78.982  1.00 110.48 ? 49  LEU A CA  1 
ATOM   332  C  C   . LEU A 1 49  ? 121.202 100.551 78.955  1.00 110.48 ? 49  LEU A C   1 
ATOM   333  O  O   . LEU A 1 49  ? 122.221 101.071 79.423  1.00 110.48 ? 49  LEU A O   1 
ATOM   334  C  CB  . LEU A 1 49  ? 119.006 100.798 80.139  1.00 110.48 ? 49  LEU A CB  1 
ATOM   335  C  CG  . LEU A 1 49  ? 117.905 101.744 80.619  1.00 110.48 ? 49  LEU A CG  1 
ATOM   336  C  CD1 . LEU A 1 49  ? 116.879 100.992 81.452  1.00 110.48 ? 49  LEU A CD1 1 
ATOM   337  C  CD2 . LEU A 1 49  ? 118.501 102.898 81.408  1.00 110.48 ? 49  LEU A CD2 1 
ATOM   338  N  N   . GLN A 1 50  ? 121.212 99.331  78.414  1.00 119.16 ? 50  GLN A N   1 
ATOM   339  C  CA  . GLN A 1 50  ? 122.453 98.569  78.318  1.00 119.16 ? 50  GLN A CA  1 
ATOM   340  C  C   . GLN A 1 50  ? 123.444 99.255  77.386  1.00 119.16 ? 50  GLN A C   1 
ATOM   341  O  O   . GLN A 1 50  ? 124.638 99.359  77.695  1.00 119.16 ? 50  GLN A O   1 
ATOM   342  C  CB  . GLN A 1 50  ? 122.156 97.147  77.841  1.00 119.16 ? 50  GLN A CB  1 
ATOM   343  C  CG  . GLN A 1 50  ? 123.301 96.170  78.054  1.00 119.16 ? 50  GLN A CG  1 
ATOM   344  C  CD  . GLN A 1 50  ? 123.496 95.813  79.514  1.00 119.16 ? 50  GLN A CD  1 
ATOM   345  O  OE1 . GLN A 1 50  ? 122.532 95.692  80.270  1.00 119.16 ? 50  GLN A OE1 1 
ATOM   346  N  NE2 . GLN A 1 50  ? 124.749 95.641  79.919  1.00 119.16 ? 50  GLN A NE2 1 
ATOM   347  N  N   . ASP A 1 51  ? 122.963 99.739  76.239  1.00 115.52 ? 51  ASP A N   1 
ATOM   348  C  CA  . ASP A 1 51  ? 123.839 100.451 75.314  1.00 115.52 ? 51  ASP A CA  1 
ATOM   349  C  C   . ASP A 1 51  ? 124.406 101.711 75.957  1.00 115.52 ? 51  ASP A C   1 
ATOM   350  O  O   . ASP A 1 51  ? 125.568 102.067 75.731  1.00 115.52 ? 51  ASP A O   1 
ATOM   351  C  CB  . ASP A 1 51  ? 123.078 100.795 74.033  1.00 115.52 ? 51  ASP A CB  1 
ATOM   352  C  CG  . ASP A 1 51  ? 123.752 101.891 73.230  1.00 115.52 ? 51  ASP A CG  1 
ATOM   353  O  OD1 . ASP A 1 51  ? 124.962 101.764 72.943  1.00 115.52 ? 51  ASP A OD1 1 
ATOM   354  O  OD2 . ASP A 1 51  ? 123.072 102.881 72.886  1.00 115.52 ? 51  ASP A OD2 1 
ATOM   355  N  N   . MET A 1 52  ? 123.599 102.391 76.772  1.00 108.49 ? 52  MET A N   1 
ATOM   356  C  CA  . MET A 1 52  ? 124.032 103.634 77.395  1.00 108.49 ? 52  MET A CA  1 
ATOM   357  C  C   . MET A 1 52  ? 125.008 103.370 78.536  1.00 108.49 ? 52  MET A C   1 
ATOM   358  O  O   . MET A 1 52  ? 125.904 104.182 78.794  1.00 108.49 ? 52  MET A O   1 
ATOM   359  C  CB  . MET A 1 52  ? 122.807 104.402 77.890  1.00 108.49 ? 52  MET A CB  1 
ATOM   360  C  CG  . MET A 1 52  ? 122.551 105.709 77.161  1.00 108.49 ? 52  MET A CG  1 
ATOM   361  S  SD  . MET A 1 52  ? 121.080 106.554 77.772  1.00 108.49 ? 52  MET A SD  1 
ATOM   362  C  CE  . MET A 1 52  ? 120.617 107.512 76.332  1.00 108.49 ? 52  MET A CE  1 
ATOM   363  N  N   . ILE A 1 53  ? 124.850 102.242 79.231  1.00 109.69 ? 53  ILE A N   1 
ATOM   364  C  CA  . ILE A 1 53  ? 125.730 101.943 80.356  1.00 109.69 ? 53  ILE A CA  1 
ATOM   365  C  C   . ILE A 1 53  ? 127.052 101.364 79.865  1.00 109.69 ? 53  ILE A C   1 
ATOM   366  O  O   . ILE A 1 53  ? 128.090 101.518 80.519  1.00 109.69 ? 53  ILE A O   1 
ATOM   367  C  CB  . ILE A 1 53  ? 125.027 101.004 81.355  1.00 109.69 ? 53  ILE A CB  1 
ATOM   368  C  CG1 . ILE A 1 53  ? 125.795 100.955 82.674  1.00 109.69 ? 53  ILE A CG1 1 
ATOM   369  C  CG2 . ILE A 1 53  ? 124.892 99.601  80.796  1.00 109.69 ? 53  ILE A CG2 1 
ATOM   370  C  CD1 . ILE A 1 53  ? 124.900 100.951 83.879  1.00 109.69 ? 53  ILE A CD1 1 
ATOM   371  N  N   . ASN A 1 54  ? 127.041 100.691 78.710  1.00 112.22 ? 54  ASN A N   1 
ATOM   372  C  CA  . ASN A 1 54  ? 128.292 100.180 78.157  1.00 112.22 ? 54  ASN A CA  1 
ATOM   373  C  C   . ASN A 1 54  ? 129.236 101.310 77.765  1.00 112.22 ? 54  ASN A C   1 
ATOM   374  O  O   . ASN A 1 54  ? 130.451 101.193 77.957  1.00 112.22 ? 54  ASN A O   1 
ATOM   375  C  CB  . ASN A 1 54  ? 128.016 99.277  76.955  1.00 112.22 ? 54  ASN A CB  1 
ATOM   376  C  CG  . ASN A 1 54  ? 127.301 97.996  77.339  1.00 112.22 ? 54  ASN A CG  1 
ATOM   377  O  OD1 . ASN A 1 54  ? 126.437 97.511  76.610  1.00 112.22 ? 54  ASN A OD1 1 
ATOM   378  N  ND2 . ASN A 1 54  ? 127.659 97.443  78.492  1.00 112.22 ? 54  ASN A ND2 1 
ATOM   379  N  N   . GLU A 1 55  ? 128.702 102.403 77.220  1.00 113.36 ? 55  GLU A N   1 
ATOM   380  C  CA  . GLU A 1 55  ? 129.526 103.535 76.817  1.00 113.36 ? 55  GLU A CA  1 
ATOM   381  C  C   . GLU A 1 55  ? 129.940 104.419 77.986  1.00 113.36 ? 55  GLU A C   1 
ATOM   382  O  O   . GLU A 1 55  ? 130.802 105.287 77.807  1.00 113.36 ? 55  GLU A O   1 
ATOM   383  C  CB  . GLU A 1 55  ? 128.785 104.381 75.778  1.00 113.36 ? 55  GLU A CB  1 
ATOM   384  C  CG  . GLU A 1 55  ? 127.784 105.358 76.376  1.00 113.36 ? 55  GLU A CG  1 
ATOM   385  C  CD  . GLU A 1 55  ? 126.684 105.735 75.404  1.00 113.36 ? 55  GLU A CD  1 
ATOM   386  O  OE1 . GLU A 1 55  ? 125.963 104.829 74.939  1.00 113.36 ? 55  GLU A OE1 1 
ATOM   387  O  OE2 . GLU A 1 55  ? 126.539 106.940 75.109  1.00 113.36 ? 55  GLU A OE2 1 
ATOM   388  N  N   . VAL A 1 56  ? 129.357 104.226 79.166  1.00 109.59 ? 56  VAL A N   1 
ATOM   389  C  CA  . VAL A 1 56  ? 129.664 105.068 80.315  1.00 109.59 ? 56  VAL A CA  1 
ATOM   390  C  C   . VAL A 1 56  ? 130.358 104.314 81.441  1.00 109.59 ? 56  VAL A C   1 
ATOM   391  O  O   . VAL A 1 56  ? 130.959 104.958 82.318  1.00 109.59 ? 56  VAL A O   1 
ATOM   392  C  CB  . VAL A 1 56  ? 128.391 105.763 80.845  1.00 109.59 ? 56  VAL A CB  1 
ATOM   393  C  CG1 . VAL A 1 56  ? 127.635 104.848 81.800  1.00 109.59 ? 56  VAL A CG1 1 
ATOM   394  C  CG2 . VAL A 1 56  ? 128.739 107.086 81.512  1.00 109.59 ? 56  VAL A CG2 1 
ATOM   395  N  N   . ASP A 1 57  ? 130.316 102.984 81.460  1.00 115.80 ? 57  ASP A N   1 
ATOM   396  C  CA  . ASP A 1 57  ? 130.978 102.186 82.482  1.00 115.80 ? 57  ASP A CA  1 
ATOM   397  C  C   . ASP A 1 57  ? 132.004 101.281 81.817  1.00 115.80 ? 57  ASP A C   1 
ATOM   398  O  O   . ASP A 1 57  ? 131.701 100.624 80.815  1.00 115.80 ? 57  ASP A O   1 
ATOM   399  C  CB  . ASP A 1 57  ? 129.968 101.355 83.277  1.00 115.80 ? 57  ASP A CB  1 
ATOM   400  C  CG  . ASP A 1 57  ? 130.423 101.089 84.699  1.00 115.80 ? 57  ASP A CG  1 
ATOM   401  O  OD1 . ASP A 1 57  ? 131.573 101.444 85.032  1.00 115.80 ? 57  ASP A OD1 1 
ATOM   402  O  OD2 . ASP A 1 57  ? 129.631 100.525 85.483  1.00 115.80 ? 57  ASP A OD2 1 
ATOM   403  N  N   . ALA A 1 58  ? 133.212 101.250 82.372  1.00 117.64 ? 58  ALA A N   1 
ATOM   404  C  CA  . ALA A 1 58  ? 134.303 100.455 81.822  1.00 117.64 ? 58  ALA A CA  1 
ATOM   405  C  C   . ALA A 1 58  ? 134.851 99.426  82.796  1.00 117.64 ? 58  ALA A C   1 
ATOM   406  O  O   . ALA A 1 58  ? 135.154 98.301  82.389  1.00 117.64 ? 58  ALA A O   1 
ATOM   407  C  CB  . ALA A 1 58  ? 135.443 101.373 81.358  1.00 117.64 ? 58  ALA A CB  1 
ATOM   408  N  N   . ASP A 1 59  ? 134.989 99.777  84.072  1.00 114.73 ? 59  ASP A N   1 
ATOM   409  C  CA  . ASP A 1 59  ? 135.516 98.863  85.076  1.00 114.73 ? 59  ASP A CA  1 
ATOM   410  C  C   . ASP A 1 59  ? 134.428 98.085  85.803  1.00 114.73 ? 59  ASP A C   1 
ATOM   411  O  O   . ASP A 1 59  ? 134.746 97.283  86.687  1.00 114.73 ? 59  ASP A O   1 
ATOM   412  C  CB  . ASP A 1 59  ? 136.362 99.634  86.096  1.00 114.73 ? 59  ASP A CB  1 
ATOM   413  C  CG  . ASP A 1 59  ? 137.223 100.701 85.452  1.00 114.73 ? 59  ASP A CG  1 
ATOM   414  O  OD1 . ASP A 1 59  ? 138.322 100.365 84.962  1.00 114.73 ? 59  ASP A OD1 1 
ATOM   415  O  OD2 . ASP A 1 59  ? 136.802 101.876 85.434  1.00 114.73 ? 59  ASP A OD2 1 
ATOM   416  N  N   . GLY A 1 60  ? 133.162 98.295  85.453  1.00 109.69 ? 60  GLY A N   1 
ATOM   417  C  CA  . GLY A 1 60  ? 132.076 97.625  86.150  1.00 109.69 ? 60  GLY A CA  1 
ATOM   418  C  C   . GLY A 1 60  ? 131.931 98.055  87.593  1.00 109.69 ? 60  GLY A C   1 
ATOM   419  O  O   . GLY A 1 60  ? 131.600 97.232  88.456  1.00 109.69 ? 60  GLY A O   1 
ATOM   420  N  N   . ASN A 1 61  ? 132.175 99.337  87.878  1.00 113.25 ? 61  ASN A N   1 
ATOM   421  C  CA  . ASN A 1 61  ? 132.062 99.827  89.247  1.00 113.25 ? 61  ASN A CA  1 
ATOM   422  C  C   . ASN A 1 61  ? 130.611 99.899  89.704  1.00 113.25 ? 61  ASN A C   1 
ATOM   423  O  O   . ASN A 1 61  ? 130.324 99.690  90.888  1.00 113.25 ? 61  ASN A O   1 
ATOM   424  C  CB  . ASN A 1 61  ? 132.722 101.200 89.370  1.00 113.25 ? 61  ASN A CB  1 
ATOM   425  C  CG  . ASN A 1 61  ? 134.087 101.250 88.716  1.00 113.25 ? 61  ASN A CG  1 
ATOM   426  O  OD1 . ASN A 1 61  ? 134.223 101.677 87.570  1.00 113.25 ? 61  ASN A OD1 1 
ATOM   427  N  ND2 . ASN A 1 61  ? 135.108 100.811 89.442  1.00 113.25 ? 61  ASN A ND2 1 
ATOM   428  N  N   . GLY A 1 62  ? 129.688 100.189 88.790  1.00 110.82 ? 62  GLY A N   1 
ATOM   429  C  CA  . GLY A 1 62  ? 128.294 100.324 89.155  1.00 110.82 ? 62  GLY A CA  1 
ATOM   430  C  C   . GLY A 1 62  ? 127.935 101.626 89.831  1.00 110.82 ? 62  GLY A C   1 
ATOM   431  O  O   . GLY A 1 62  ? 126.907 101.693 90.511  1.00 110.82 ? 62  GLY A O   1 
ATOM   432  N  N   . THR A 1 63  ? 128.748 102.667 89.666  1.00 110.72 ? 63  THR A N   1 
ATOM   433  C  CA  . THR A 1 63  ? 128.488 103.968 90.264  1.00 110.72 ? 63  THR A CA  1 
ATOM   434  C  C   . THR A 1 63  ? 128.513 105.044 89.188  1.00 110.72 ? 63  THR A C   1 
ATOM   435  O  O   . THR A 1 63  ? 129.360 105.021 88.290  1.00 110.72 ? 63  THR A O   1 
ATOM   436  C  CB  . THR A 1 63  ? 129.510 104.294 91.366  1.00 110.72 ? 63  THR A CB  1 
ATOM   437  O  OG1 . THR A 1 63  ? 129.332 105.646 91.805  1.00 110.72 ? 63  THR A OG1 1 
ATOM   438  C  CG2 . THR A 1 63  ? 130.934 104.104 90.861  1.00 110.72 ? 63  THR A CG2 1 
ATOM   439  N  N   . ILE A 1 64  ? 127.569 105.978 89.278  1.00 106.05 ? 64  ILE A N   1 
ATOM   440  C  CA  . ILE A 1 64  ? 127.442 107.079 88.328  1.00 106.05 ? 64  ILE A CA  1 
ATOM   441  C  C   . ILE A 1 64  ? 127.177 108.354 89.115  1.00 106.05 ? 64  ILE A C   1 
ATOM   442  O  O   . ILE A 1 64  ? 126.312 108.372 89.996  1.00 106.05 ? 64  ILE A O   1 
ATOM   443  C  CB  . ILE A 1 64  ? 126.312 106.825 87.310  1.00 106.05 ? 64  ILE A CB  1 
ATOM   444  C  CG1 . ILE A 1 64  ? 126.703 105.710 86.338  1.00 106.05 ? 64  ILE A CG1 1 
ATOM   445  C  CG2 . ILE A 1 64  ? 125.966 108.099 86.555  1.00 106.05 ? 64  ILE A CG2 1 
ATOM   446  C  CD1 . ILE A 1 64  ? 127.893 106.042 85.471  1.00 106.05 ? 64  ILE A CD1 1 
ATOM   447  N  N   . ASP A 1 65  ? 127.913 109.417 88.803  1.00 103.37 ? 65  ASP A N   1 
ATOM   448  C  CA  . ASP A 1 65  ? 127.747 110.696 89.479  1.00 103.37 ? 65  ASP A CA  1 
ATOM   449  C  C   . ASP A 1 65  ? 127.009 111.681 88.573  1.00 103.37 ? 65  ASP A C   1 
ATOM   450  O  O   . ASP A 1 65  ? 126.593 111.352 87.458  1.00 103.37 ? 65  ASP A O   1 
ATOM   451  C  CB  . ASP A 1 65  ? 129.101 111.246 89.946  1.00 103.37 ? 65  ASP A CB  1 
ATOM   452  C  CG  . ASP A 1 65  ? 129.970 111.741 88.805  1.00 103.37 ? 65  ASP A CG  1 
ATOM   453  O  OD1 . ASP A 1 65  ? 129.740 111.343 87.647  1.00 103.37 ? 65  ASP A OD1 1 
ATOM   454  O  OD2 . ASP A 1 65  ? 130.894 112.538 89.071  1.00 103.37 ? 65  ASP A OD2 1 
ATOM   455  N  N   . PHE A 1 66  ? 126.849 112.904 89.076  1.00 91.64  ? 66  PHE A N   1 
ATOM   456  C  CA  . PHE A 1 66  ? 125.959 113.874 88.437  1.00 91.64  ? 66  PHE A CA  1 
ATOM   457  C  C   . PHE A 1 66  ? 126.385 114.285 87.029  1.00 91.64  ? 66  PHE A C   1 
ATOM   458  O  O   . PHE A 1 66  ? 125.517 114.314 86.138  1.00 91.64  ? 66  PHE A O   1 
ATOM   459  C  CB  . PHE A 1 66  ? 125.810 115.095 89.351  1.00 91.64  ? 66  PHE A CB  1 
ATOM   460  C  CG  . PHE A 1 66  ? 124.655 115.985 88.992  1.00 91.64  ? 66  PHE A CG  1 
ATOM   461  C  CD1 . PHE A 1 66  ? 123.533 115.470 88.367  1.00 91.64  ? 66  PHE A CD1 1 
ATOM   462  C  CD2 . PHE A 1 66  ? 124.687 117.337 89.291  1.00 91.64  ? 66  PHE A CD2 1 
ATOM   463  C  CE1 . PHE A 1 66  ? 122.469 116.287 88.039  1.00 91.64  ? 66  PHE A CE1 1 
ATOM   464  C  CE2 . PHE A 1 66  ? 123.626 118.158 88.966  1.00 91.64  ? 66  PHE A CE2 1 
ATOM   465  C  CZ  . PHE A 1 66  ? 122.515 117.632 88.339  1.00 91.64  ? 66  PHE A CZ  1 
ATOM   466  N  N   . PRO A 1 67  ? 127.650 114.643 86.755  1.00 96.89  ? 67  PRO A N   1 
ATOM   467  C  CA  . PRO A 1 67  ? 127.970 115.167 85.411  1.00 96.89  ? 67  PRO A CA  1 
ATOM   468  C  C   . PRO A 1 67  ? 127.695 114.194 84.276  1.00 96.89  ? 67  PRO A C   1 
ATOM   469  O  O   . PRO A 1 67  ? 127.159 114.604 83.235  1.00 96.89  ? 67  PRO A O   1 
ATOM   470  C  CB  . PRO A 1 67  ? 129.466 115.505 85.515  1.00 96.89  ? 67  PRO A CB  1 
ATOM   471  C  CG  . PRO A 1 67  ? 129.962 114.737 86.690  1.00 96.89  ? 67  PRO A CG  1 
ATOM   472  C  CD  . PRO A 1 67  ? 128.820 114.712 87.647  1.00 96.89  ? 67  PRO A CD  1 
ATOM   473  N  N   . GLU A 1 68  ? 128.044 112.915 84.435  1.00 98.40  ? 68  GLU A N   1 
ATOM   474  C  CA  . GLU A 1 68  ? 127.775 111.969 83.359  1.00 98.40  ? 68  GLU A CA  1 
ATOM   475  C  C   . GLU A 1 68  ? 126.283 111.726 83.188  1.00 98.40  ? 68  GLU A C   1 
ATOM   476  O  O   . GLU A 1 68  ? 125.823 111.521 82.061  1.00 98.40  ? 68  GLU A O   1 
ATOM   477  C  CB  . GLU A 1 68  ? 128.507 110.646 83.595  1.00 98.40  ? 68  GLU A CB  1 
ATOM   478  C  CG  . GLU A 1 68  ? 128.547 110.172 85.030  1.00 98.40  ? 68  GLU A CG  1 
ATOM   479  C  CD  . GLU A 1 68  ? 129.586 109.087 85.244  1.00 98.40  ? 68  GLU A CD  1 
ATOM   480  O  OE1 . GLU A 1 68  ? 129.901 108.369 84.273  1.00 98.40  ? 68  GLU A OE1 1 
ATOM   481  O  OE2 . GLU A 1 68  ? 130.083 108.945 86.380  1.00 98.40  ? 68  GLU A OE2 1 
ATOM   482  N  N   . PHE A 1 69  ? 125.514 111.760 84.279  1.00 92.51  ? 69  PHE A N   1 
ATOM   483  C  CA  . PHE A 1 69  ? 124.063 111.686 84.152  1.00 92.51  ? 69  PHE A CA  1 
ATOM   484  C  C   . PHE A 1 69  ? 123.520 112.878 83.376  1.00 92.51  ? 69  PHE A C   1 
ATOM   485  O  O   . PHE A 1 69  ? 122.615 112.729 82.547  1.00 92.51  ? 69  PHE A O   1 
ATOM   486  C  CB  . PHE A 1 69  ? 123.410 111.612 85.532  1.00 92.51  ? 69  PHE A CB  1 
ATOM   487  C  CG  . PHE A 1 69  ? 121.915 111.757 85.500  1.00 92.51  ? 69  PHE A CG  1 
ATOM   488  C  CD1 . PHE A 1 69  ? 121.136 110.883 84.763  1.00 92.51  ? 69  PHE A CD1 1 
ATOM   489  C  CD2 . PHE A 1 69  ? 121.289 112.780 86.192  1.00 92.51  ? 69  PHE A CD2 1 
ATOM   490  C  CE1 . PHE A 1 69  ? 119.762 111.017 84.728  1.00 92.51  ? 69  PHE A CE1 1 
ATOM   491  C  CE2 . PHE A 1 69  ? 119.916 112.918 86.162  1.00 92.51  ? 69  PHE A CE2 1 
ATOM   492  C  CZ  . PHE A 1 69  ? 119.152 112.037 85.428  1.00 92.51  ? 69  PHE A CZ  1 
ATOM   493  N  N   . LEU A 1 70  ? 124.055 114.072 83.640  1.00 91.37  ? 70  LEU A N   1 
ATOM   494  C  CA  . LEU A 1 70  ? 123.617 115.258 82.911  1.00 91.37  ? 70  LEU A CA  1 
ATOM   495  C  C   . LEU A 1 70  ? 123.924 115.130 81.425  1.00 91.37  ? 70  LEU A C   1 
ATOM   496  O  O   . LEU A 1 70  ? 123.080 115.439 80.575  1.00 91.37  ? 70  LEU A O   1 
ATOM   497  C  CB  . LEU A 1 70  ? 124.281 116.507 83.491  1.00 91.37  ? 70  LEU A CB  1 
ATOM   498  C  CG  . LEU A 1 70  ? 123.645 117.107 84.746  1.00 91.37  ? 70  LEU A CG  1 
ATOM   499  C  CD1 . LEU A 1 70  ? 124.617 118.050 85.435  1.00 91.37  ? 70  LEU A CD1 1 
ATOM   500  C  CD2 . LEU A 1 70  ? 122.351 117.826 84.400  1.00 91.37  ? 70  LEU A CD2 1 
ATOM   501  N  N   . THR A 1 71  ? 125.133 114.669 81.094  1.00 98.49  ? 71  THR A N   1 
ATOM   502  C  CA  . THR A 1 71  ? 125.485 114.477 79.689  1.00 98.49  ? 71  THR A CA  1 
ATOM   503  C  C   . THR A 1 71  ? 124.599 113.422 79.035  1.00 98.49  ? 71  THR A C   1 
ATOM   504  O  O   . THR A 1 71  ? 124.159 113.593 77.890  1.00 98.49  ? 71  THR A O   1 
ATOM   505  C  CB  . THR A 1 71  ? 126.959 114.091 79.556  1.00 98.49  ? 71  THR A CB  1 
ATOM   506  O  OG1 . THR A 1 71  ? 127.186 112.830 80.199  1.00 98.49  ? 71  THR A OG1 1 
ATOM   507  C  CG2 . THR A 1 71  ? 127.851 115.153 80.181  1.00 98.49  ? 71  THR A CG2 1 
ATOM   508  N  N   . MET A 1 72  ? 124.325 112.330 79.750  1.00 101.74 ? 72  MET A N   1 
ATOM   509  C  CA  . MET A 1 72  ? 123.477 111.271 79.214  1.00 101.74 ? 72  MET A CA  1 
ATOM   510  C  C   . MET A 1 72  ? 122.071 111.786 78.938  1.00 101.74 ? 72  MET A C   1 
ATOM   511  O  O   . MET A 1 72  ? 121.486 111.502 77.885  1.00 101.74 ? 72  MET A O   1 
ATOM   512  C  CB  . MET A 1 72  ? 123.439 110.102 80.198  1.00 101.74 ? 72  MET A CB  1 
ATOM   513  C  CG  . MET A 1 72  ? 123.045 108.777 79.586  1.00 101.74 ? 72  MET A CG  1 
ATOM   514  S  SD  . MET A 1 72  ? 124.479 107.720 79.322  1.00 101.74 ? 72  MET A SD  1 
ATOM   515  C  CE  . MET A 1 72  ? 125.110 107.593 80.993  1.00 101.74 ? 72  MET A CE  1 
ATOM   516  N  N   . MET A 1 73  ? 121.512 112.553 79.876  1.00 99.79  ? 73  MET A N   1 
ATOM   517  C  CA  . MET A 1 73  ? 120.169 113.083 79.680  1.00 99.79  ? 73  MET A CA  1 
ATOM   518  C  C   . MET A 1 73  ? 120.140 114.103 78.551  1.00 99.79  ? 73  MET A C   1 
ATOM   519  O  O   . MET A 1 73  ? 119.167 114.166 77.793  1.00 99.79  ? 73  MET A O   1 
ATOM   520  C  CB  . MET A 1 73  ? 119.640 113.709 80.968  1.00 99.79  ? 73  MET A CB  1 
ATOM   521  C  CG  . MET A 1 73  ? 118.545 112.896 81.623  1.00 99.79  ? 73  MET A CG  1 
ATOM   522  S  SD  . MET A 1 73  ? 117.071 112.796 80.590  1.00 99.79  ? 73  MET A SD  1 
ATOM   523  C  CE  . MET A 1 73  ? 116.577 114.509 80.469  1.00 99.79  ? 73  MET A CE  1 
ATOM   524  N  N   . ALA A 1 74  ? 121.192 114.917 78.428  1.00 101.75 ? 74  ALA A N   1 
ATOM   525  C  CA  . ALA A 1 74  ? 121.261 115.866 77.323  1.00 101.75 ? 74  ALA A CA  1 
ATOM   526  C  C   . ALA A 1 74  ? 121.298 115.142 75.984  1.00 101.75 ? 74  ALA A C   1 
ATOM   527  O  O   . ALA A 1 74  ? 120.655 115.571 75.019  1.00 101.75 ? 74  ALA A O   1 
ATOM   528  C  CB  . ALA A 1 74  ? 122.481 116.771 77.481  1.00 101.75 ? 74  ALA A CB  1 
ATOM   529  N  N   . ARG A 1 75  ? 122.050 114.043 75.907  1.00 106.58 ? 75  ARG A N   1 
ATOM   530  C  CA  . ARG A 1 75  ? 122.083 113.253 74.680  1.00 106.58 ? 75  ARG A CA  1 
ATOM   531  C  C   . ARG A 1 75  ? 120.721 112.630 74.388  1.00 106.58 ? 75  ARG A C   1 
ATOM   532  O  O   . ARG A 1 75  ? 120.270 112.604 73.237  1.00 106.58 ? 75  ARG A O   1 
ATOM   533  C  CB  . ARG A 1 75  ? 123.157 112.171 74.784  1.00 106.58 ? 75  ARG A CB  1 
ATOM   534  C  CG  . ARG A 1 75  ? 124.579 112.700 74.717  1.00 106.58 ? 75  ARG A CG  1 
ATOM   535  C  CD  . ARG A 1 75  ? 125.591 111.576 74.872  1.00 106.58 ? 75  ARG A CD  1 
ATOM   536  N  N   . LYS A 1 76  ? 120.048 112.125 75.425  1.00 109.80 ? 76  LYS A N   1 
ATOM   537  C  CA  . LYS A 1 76  ? 118.799 111.397 75.214  1.00 109.80 ? 76  LYS A CA  1 
ATOM   538  C  C   . LYS A 1 76  ? 117.633 112.328 74.893  1.00 109.80 ? 76  LYS A C   1 
ATOM   539  O  O   . LYS A 1 76  ? 116.722 111.942 74.151  1.00 109.80 ? 76  LYS A O   1 
ATOM   540  C  CB  . LYS A 1 76  ? 118.478 110.548 76.444  1.00 109.80 ? 76  LYS A CB  1 
ATOM   541  C  CG  . LYS A 1 76  ? 117.200 109.732 76.331  1.00 109.80 ? 76  LYS A CG  1 
ATOM   542  C  CD  . LYS A 1 76  ? 117.247 108.794 75.136  1.00 109.80 ? 76  LYS A CD  1 
ATOM   543  C  CE  . LYS A 1 76  ? 115.849 108.443 74.655  1.00 109.80 ? 76  LYS A CE  1 
ATOM   544  N  NZ  . LYS A 1 76  ? 115.250 109.538 73.845  1.00 109.80 ? 76  LYS A NZ  1 
ATOM   545  N  N   . MET A 1 77  ? 117.643 113.551 75.429  1.00 116.52 ? 77  MET A N   1 
ATOM   546  C  CA  . MET A 1 77  ? 116.516 114.468 75.294  1.00 116.52 ? 77  MET A CA  1 
ATOM   547  C  C   . MET A 1 77  ? 116.246 114.875 73.849  1.00 116.52 ? 77  MET A C   1 
ATOM   548  O  O   . MET A 1 77  ? 115.134 115.322 73.546  1.00 116.52 ? 77  MET A O   1 
ATOM   549  C  CB  . MET A 1 77  ? 116.774 115.703 76.170  1.00 116.52 ? 77  MET A CB  1 
ATOM   550  C  CG  . MET A 1 77  ? 115.790 116.856 76.016  1.00 116.52 ? 77  MET A CG  1 
ATOM   551  S  SD  . MET A 1 77  ? 116.357 118.120 74.862  1.00 116.52 ? 77  MET A SD  1 
ATOM   552  C  CE  . MET A 1 77  ? 117.189 119.248 75.977  1.00 116.52 ? 77  MET A CE  1 
ATOM   553  N  N   . LYS A 1 78  ? 117.210 114.687 72.945  1.00 123.25 ? 78  LYS A N   1 
ATOM   554  C  CA  . LYS A 1 78  ? 117.078 115.153 71.569  1.00 123.25 ? 78  LYS A CA  1 
ATOM   555  C  C   . LYS A 1 78  ? 115.923 114.499 70.819  1.00 123.25 ? 78  LYS A C   1 
ATOM   556  O  O   . LYS A 1 78  ? 115.505 115.032 69.785  1.00 123.25 ? 78  LYS A O   1 
ATOM   557  C  CB  . LYS A 1 78  ? 118.387 114.914 70.816  1.00 123.25 ? 78  LYS A CB  1 
ATOM   558  C  CG  . LYS A 1 78  ? 119.561 115.706 71.368  1.00 123.25 ? 78  LYS A CG  1 
ATOM   559  C  CD  . LYS A 1 78  ? 120.831 115.454 70.574  1.00 123.25 ? 78  LYS A CD  1 
ATOM   560  C  CE  . LYS A 1 78  ? 121.968 116.335 71.068  1.00 123.25 ? 78  LYS A CE  1 
ATOM   561  N  NZ  . LYS A 1 78  ? 123.221 116.112 70.296  1.00 123.25 ? 78  LYS A NZ  1 
ATOM   562  N  N   . ASP A 1 79  ? 115.401 113.373 71.301  1.00 128.66 ? 79  ASP A N   1 
ATOM   563  C  CA  . ASP A 1 79  ? 114.262 112.718 70.674  1.00 128.66 ? 79  ASP A CA  1 
ATOM   564  C  C   . ASP A 1 79  ? 113.171 112.505 71.713  1.00 128.66 ? 79  ASP A C   1 
ATOM   565  O  O   . ASP A 1 79  ? 113.460 112.195 72.872  1.00 128.66 ? 79  ASP A O   1 
ATOM   566  C  CB  . ASP A 1 79  ? 114.660 111.377 70.044  1.00 128.66 ? 79  ASP A CB  1 
ATOM   567  C  CG  . ASP A 1 79  ? 113.897 111.085 68.766  1.00 128.66 ? 79  ASP A CG  1 
ATOM   568  O  OD1 . ASP A 1 79  ? 113.295 112.024 68.204  1.00 128.66 ? 79  ASP A OD1 1 
ATOM   569  O  OD2 . ASP A 1 79  ? 113.901 109.917 68.323  1.00 128.66 ? 79  ASP A OD2 1 
ATOM   570  N  N   . THR A 1 80  ? 111.919 112.671 71.291  1.00 134.78 ? 80  THR A N   1 
ATOM   571  C  CA  . THR A 1 80  ? 110.784 112.523 72.191  1.00 134.78 ? 80  THR A CA  1 
ATOM   572  C  C   . THR A 1 80  ? 109.561 112.093 71.394  1.00 134.78 ? 80  THR A C   1 
ATOM   573  O  O   . THR A 1 80  ? 109.504 112.251 70.171  1.00 134.78 ? 80  THR A O   1 
ATOM   574  C  CB  . THR A 1 80  ? 110.494 113.821 72.956  1.00 134.78 ? 80  THR A CB  1 
ATOM   575  O  OG1 . THR A 1 80  ? 109.511 113.572 73.970  1.00 134.78 ? 80  THR A OG1 1 
ATOM   576  C  CG2 . THR A 1 80  ? 109.980 114.896 72.010  1.00 134.78 ? 80  THR A CG2 1 
ATOM   577  N  N   . ASP A 1 81  ? 108.580 111.545 72.107  1.00 130.26 ? 81  ASP A N   1 
ATOM   578  C  CA  . ASP A 1 81  ? 107.341 111.058 71.517  1.00 130.26 ? 81  ASP A CA  1 
ATOM   579  C  C   . ASP A 1 81  ? 106.152 111.641 72.266  1.00 130.26 ? 81  ASP A C   1 
ATOM   580  O  O   . ASP A 1 81  ? 106.255 111.975 73.451  1.00 130.26 ? 81  ASP A O   1 
ATOM   581  C  CB  . ASP A 1 81  ? 107.273 109.526 71.549  1.00 130.26 ? 81  ASP A CB  1 
ATOM   582  C  CG  . ASP A 1 81  ? 108.536 108.873 71.021  1.00 130.26 ? 81  ASP A CG  1 
ATOM   583  O  OD1 . ASP A 1 81  ? 109.103 109.381 70.032  1.00 130.26 ? 81  ASP A OD1 1 
ATOM   584  O  OD2 . ASP A 1 81  ? 108.961 107.849 71.597  1.00 130.26 ? 81  ASP A OD2 1 
ATOM   585  N  N   . SER A 1 82  ? 105.025 111.761 71.571  1.00 126.98 ? 82  SER A N   1 
ATOM   586  C  CA  . SER A 1 82  ? 103.800 112.266 72.169  1.00 126.98 ? 82  SER A CA  1 
ATOM   587  C  C   . SER A 1 82  ? 102.916 111.111 72.636  1.00 126.98 ? 82  SER A C   1 
ATOM   588  O  O   . SER A 1 82  ? 103.232 109.934 72.453  1.00 126.98 ? 82  SER A O   1 
ATOM   589  C  CB  . SER A 1 82  ? 103.046 113.155 71.179  1.00 126.98 ? 82  SER A CB  1 
ATOM   590  O  OG  . SER A 1 82  ? 102.324 112.378 70.241  1.00 126.98 ? 82  SER A OG  1 
ATOM   591  N  N   . GLU A 1 83  ? 101.785 111.467 73.251  1.00 123.92 ? 83  GLU A N   1 
ATOM   592  C  CA  . GLU A 1 83  ? 100.879 110.458 73.790  1.00 123.92 ? 83  GLU A CA  1 
ATOM   593  C  C   . GLU A 1 83  ? 99.903  109.930 72.746  1.00 123.92 ? 83  GLU A C   1 
ATOM   594  O  O   . GLU A 1 83  ? 99.169  108.978 73.031  1.00 123.92 ? 83  GLU A O   1 
ATOM   595  C  CB  . GLU A 1 83  ? 100.104 111.031 74.978  1.00 123.92 ? 83  GLU A CB  1 
ATOM   596  C  CG  . GLU A 1 83  ? 100.978 111.681 76.039  1.00 123.92 ? 83  GLU A CG  1 
ATOM   597  C  CD  . GLU A 1 83  ? 101.126 113.176 75.838  1.00 123.92 ? 83  GLU A CD  1 
ATOM   598  O  OE1 . GLU A 1 83  ? 101.115 113.626 74.673  1.00 123.92 ? 83  GLU A OE1 1 
ATOM   599  O  OE2 . GLU A 1 83  ? 101.252 113.904 76.845  1.00 123.92 ? 83  GLU A OE2 1 
ATOM   600  N  N   . GLU A 1 84  ? 99.873  110.524 71.551  1.00 126.18 ? 84  GLU A N   1 
ATOM   601  C  CA  . GLU A 1 84  ? 98.944  110.069 70.523  1.00 126.18 ? 84  GLU A CA  1 
ATOM   602  C  C   . GLU A 1 84  ? 99.328  108.693 69.989  1.00 126.18 ? 84  GLU A C   1 
ATOM   603  O  O   . GLU A 1 84  ? 98.449  107.871 69.708  1.00 126.18 ? 84  GLU A O   1 
ATOM   604  C  CB  . GLU A 1 84  ? 98.888  111.089 69.385  1.00 126.18 ? 84  GLU A CB  1 
ATOM   605  C  CG  . GLU A 1 84  ? 97.933  110.740 68.250  1.00 126.18 ? 84  GLU A CG  1 
ATOM   606  C  CD  . GLU A 1 84  ? 96.605  110.192 68.742  1.00 126.18 ? 84  GLU A CD  1 
ATOM   607  O  OE1 . GLU A 1 84  ? 96.308  109.009 68.478  1.00 126.18 ? 84  GLU A OE1 1 
ATOM   608  O  OE2 . GLU A 1 84  ? 95.856  110.949 69.397  1.00 126.18 ? 84  GLU A OE2 1 
ATOM   609  N  N   . GLU A 1 85  ? 100.627 108.419 69.859  1.00 123.29 ? 85  GLU A N   1 
ATOM   610  C  CA  . GLU A 1 85  ? 101.090 107.154 69.299  1.00 123.29 ? 85  GLU A CA  1 
ATOM   611  C  C   . GLU A 1 85  ? 100.795 105.960 70.198  1.00 123.29 ? 85  GLU A C   1 
ATOM   612  O  O   . GLU A 1 85  ? 100.962 104.819 69.755  1.00 123.29 ? 85  GLU A O   1 
ATOM   613  C  CB  . GLU A 1 85  ? 102.591 107.223 69.013  1.00 123.29 ? 85  GLU A CB  1 
ATOM   614  C  CG  . GLU A 1 85  ? 103.014 108.414 68.168  1.00 123.29 ? 85  GLU A CG  1 
ATOM   615  C  CD  . GLU A 1 85  ? 103.330 109.640 69.003  1.00 123.29 ? 85  GLU A CD  1 
ATOM   616  O  OE1 . GLU A 1 85  ? 102.385 110.246 69.550  1.00 123.29 ? 85  GLU A OE1 1 
ATOM   617  O  OE2 . GLU A 1 85  ? 104.522 109.996 69.113  1.00 123.29 ? 85  GLU A OE2 1 
ATOM   618  N  N   . ILE A 1 86  ? 100.385 106.190 71.447  1.00 119.41 ? 86  ILE A N   1 
ATOM   619  C  CA  . ILE A 1 86  ? 100.021 105.081 72.323  1.00 119.41 ? 86  ILE A CA  1 
ATOM   620  C  C   . ILE A 1 86  ? 98.739  104.410 71.843  1.00 119.41 ? 86  ILE A C   1 
ATOM   621  O  O   . ILE A 1 86  ? 98.610  103.181 71.914  1.00 119.41 ? 86  ILE A O   1 
ATOM   622  C  CB  . ILE A 1 86  ? 99.900  105.581 73.776  1.00 119.41 ? 86  ILE A CB  1 
ATOM   623  C  CG1 . ILE A 1 86  ? 101.279 105.627 74.437  1.00 119.41 ? 86  ILE A CG1 1 
ATOM   624  C  CG2 . ILE A 1 86  ? 98.953  104.705 74.584  1.00 119.41 ? 86  ILE A CG2 1 
ATOM   625  C  CD1 . ILE A 1 86  ? 102.017 104.308 74.399  1.00 119.41 ? 86  ILE A CD1 1 
ATOM   626  N  N   . ARG A 1 87  ? 97.786  105.193 71.330  1.00 122.75 ? 87  ARG A N   1 
ATOM   627  C  CA  . ARG A 1 87  ? 96.477  104.650 70.976  1.00 122.75 ? 87  ARG A CA  1 
ATOM   628  C  C   . ARG A 1 87  ? 96.577  103.599 69.876  1.00 122.75 ? 87  ARG A C   1 
ATOM   629  O  O   . ARG A 1 87  ? 95.924  102.551 69.950  1.00 122.75 ? 87  ARG A O   1 
ATOM   630  C  CB  . ARG A 1 87  ? 95.539  105.780 70.548  1.00 122.75 ? 87  ARG A CB  1 
ATOM   631  C  CG  . ARG A 1 87  ? 95.717  107.082 71.318  1.00 122.75 ? 87  ARG A CG  1 
ATOM   632  C  CD  . ARG A 1 87  ? 95.478  106.899 72.811  1.00 122.75 ? 87  ARG A CD  1 
ATOM   633  N  NE  . ARG A 1 87  ? 94.358  106.006 73.081  1.00 122.75 ? 87  ARG A NE  1 
ATOM   634  C  CZ  . ARG A 1 87  ? 93.191  106.397 73.574  1.00 122.75 ? 87  ARG A CZ  1 
ATOM   635  N  NH1 . ARG A 1 87  ? 92.955  107.665 73.867  1.00 122.75 ? 87  ARG A NH1 1 
ATOM   636  N  NH2 . ARG A 1 87  ? 92.236  105.494 73.777  1.00 122.75 ? 87  ARG A NH2 1 
ATOM   637  N  N   . GLU A 1 88  ? 97.386  103.859 68.845  1.00 115.95 ? 88  GLU A N   1 
ATOM   638  C  CA  . GLU A 1 88  ? 97.482  102.918 67.733  1.00 115.95 ? 88  GLU A CA  1 
ATOM   639  C  C   . GLU A 1 88  ? 98.095  101.592 68.167  1.00 115.95 ? 88  GLU A C   1 
ATOM   640  O  O   . GLU A 1 88  ? 97.760  100.541 67.608  1.00 115.95 ? 88  GLU A O   1 
ATOM   641  C  CB  . GLU A 1 88  ? 98.290  103.530 66.588  1.00 115.95 ? 88  GLU A CB  1 
ATOM   642  C  CG  . GLU A 1 88  ? 99.633  104.101 67.004  1.00 115.95 ? 88  GLU A CG  1 
ATOM   643  C  CD  . GLU A 1 88  ? 100.423 104.649 65.832  1.00 115.95 ? 88  GLU A CD  1 
ATOM   644  O  OE1 . GLU A 1 88  ? 99.797  105.120 64.859  1.00 115.95 ? 88  GLU A OE1 1 
ATOM   645  O  OE2 . GLU A 1 88  ? 101.670 104.610 65.884  1.00 115.95 ? 88  GLU A OE2 1 
ATOM   646  N  N   . ALA A 1 89  ? 98.989  101.618 69.159  1.00 112.40 ? 89  ALA A N   1 
ATOM   647  C  CA  . ALA A 1 89  ? 99.578  100.378 69.653  1.00 112.40 ? 89  ALA A CA  1 
ATOM   648  C  C   . ALA A 1 89  ? 98.510  99.451  70.216  1.00 112.40 ? 89  ALA A C   1 
ATOM   649  O  O   . ALA A 1 89  ? 98.551  98.235  69.995  1.00 112.40 ? 89  ALA A O   1 
ATOM   650  C  CB  . ALA A 1 89  ? 100.639 100.684 70.709  1.00 112.40 ? 89  ALA A CB  1 
ATOM   651  N  N   . PHE A 1 90  ? 97.544  100.007 70.948  1.00 114.29 ? 90  PHE A N   1 
ATOM   652  C  CA  . PHE A 1 90  ? 96.420  99.212  71.426  1.00 114.29 ? 90  PHE A CA  1 
ATOM   653  C  C   . PHE A 1 90  ? 95.432  98.895  70.310  1.00 114.29 ? 90  PHE A C   1 
ATOM   654  O  O   . PHE A 1 90  ? 94.781  97.845  70.345  1.00 114.29 ? 90  PHE A O   1 
ATOM   655  C  CB  . PHE A 1 90  ? 95.707  99.942  72.564  1.00 114.29 ? 90  PHE A CB  1 
ATOM   656  C  CG  . PHE A 1 90  ? 96.475  99.948  73.855  1.00 114.29 ? 90  PHE A CG  1 
ATOM   657  C  CD1 . PHE A 1 90  ? 96.539  98.813  74.644  1.00 114.29 ? 90  PHE A CD1 1 
ATOM   658  C  CD2 . PHE A 1 90  ? 97.135  101.089 74.277  1.00 114.29 ? 90  PHE A CD2 1 
ATOM   659  C  CE1 . PHE A 1 90  ? 97.244  98.816  75.831  1.00 114.29 ? 90  PHE A CE1 1 
ATOM   660  C  CE2 . PHE A 1 90  ? 97.843  101.099 75.462  1.00 114.29 ? 90  PHE A CE2 1 
ATOM   661  C  CZ  . PHE A 1 90  ? 97.897  99.961  76.240  1.00 114.29 ? 90  PHE A CZ  1 
ATOM   662  N  N   . ARG A 1 91  ? 95.301  99.788  69.325  1.00 114.28 ? 91  ARG A N   1 
ATOM   663  C  CA  . ARG A 1 91  ? 94.374  99.548  68.223  1.00 114.28 ? 91  ARG A CA  1 
ATOM   664  C  C   . ARG A 1 91  ? 94.781  98.327  67.407  1.00 114.28 ? 91  ARG A C   1 
ATOM   665  O  O   . ARG A 1 91  ? 93.931  97.508  67.037  1.00 114.28 ? 91  ARG A O   1 
ATOM   666  C  CB  . ARG A 1 91  ? 94.290  100.784 67.327  1.00 114.28 ? 91  ARG A CB  1 
ATOM   667  C  CG  . ARG A 1 91  ? 93.499  101.935 67.925  1.00 114.28 ? 91  ARG A CG  1 
ATOM   668  C  CD  . ARG A 1 91  ? 93.602  103.182 67.062  1.00 114.28 ? 91  ARG A CD  1 
ATOM   669  N  N   . VAL A 1 92  ? 96.077  98.185  67.117  1.00 111.66 ? 92  VAL A N   1 
ATOM   670  C  CA  . VAL A 1 92  ? 96.528  97.033  66.339  1.00 111.66 ? 92  VAL A CA  1 
ATOM   671  C  C   . VAL A 1 92  ? 96.411  95.729  67.119  1.00 111.66 ? 92  VAL A C   1 
ATOM   672  O  O   . VAL A 1 92  ? 96.531  94.649  66.529  1.00 111.66 ? 92  VAL A O   1 
ATOM   673  C  CB  . VAL A 1 92  ? 97.972  97.215  65.831  1.00 111.66 ? 92  VAL A CB  1 
ATOM   674  C  CG1 . VAL A 1 92  ? 98.186  98.620  65.303  1.00 111.66 ? 92  VAL A CG1 1 
ATOM   675  C  CG2 . VAL A 1 92  ? 98.968  96.898  66.937  1.00 111.66 ? 92  VAL A CG2 1 
ATOM   676  N  N   . PHE A 1 93  ? 96.182  95.792  68.431  1.00 118.93 ? 93  PHE A N   1 
ATOM   677  C  CA  . PHE A 1 93  ? 95.998  94.578  69.215  1.00 118.93 ? 93  PHE A CA  1 
ATOM   678  C  C   . PHE A 1 93  ? 94.546  94.123  69.282  1.00 118.93 ? 93  PHE A C   1 
ATOM   679  O  O   . PHE A 1 93  ? 94.273  93.072  69.872  1.00 118.93 ? 93  PHE A O   1 
ATOM   680  C  CB  . PHE A 1 93  ? 96.541  94.773  70.632  1.00 118.93 ? 93  PHE A CB  1 
ATOM   681  C  CG  . PHE A 1 93  ? 97.996  94.437  70.770  1.00 118.93 ? 93  PHE A CG  1 
ATOM   682  C  CD1 . PHE A 1 93  ? 98.464  93.184  70.409  1.00 118.93 ? 93  PHE A CD1 1 
ATOM   683  C  CD2 . PHE A 1 93  ? 98.895  95.368  71.258  1.00 118.93 ? 93  PHE A CD2 1 
ATOM   684  C  CE1 . PHE A 1 93  ? 99.802  92.867  70.532  1.00 118.93 ? 93  PHE A CE1 1 
ATOM   685  C  CE2 . PHE A 1 93  ? 100.236 95.057  71.384  1.00 118.93 ? 93  PHE A CE2 1 
ATOM   686  C  CZ  . PHE A 1 93  ? 100.689 93.804  71.020  1.00 118.93 ? 93  PHE A CZ  1 
ATOM   687  N  N   . ASP A 1 94  ? 93.616  94.877  68.701  1.00 113.51 ? 94  ASP A N   1 
ATOM   688  C  CA  . ASP A 1 94  ? 92.210  94.481  68.657  1.00 113.51 ? 94  ASP A CA  1 
ATOM   689  C  C   . ASP A 1 94  ? 91.946  93.851  67.295  1.00 113.51 ? 94  ASP A C   1 
ATOM   690  O  O   . ASP A 1 94  ? 91.961  94.533  66.267  1.00 113.51 ? 94  ASP A O   1 
ATOM   691  C  CB  . ASP A 1 94  ? 91.302  95.678  68.914  1.00 113.51 ? 94  ASP A CB  1 
ATOM   692  C  CG  . ASP A 1 94  ? 89.930  95.270  69.409  1.00 113.51 ? 94  ASP A CG  1 
ATOM   693  O  OD1 . ASP A 1 94  ? 89.711  94.061  69.632  1.00 113.51 ? 94  ASP A OD1 1 
ATOM   694  O  OD2 . ASP A 1 94  ? 89.071  96.159  69.581  1.00 113.51 ? 94  ASP A OD2 1 
ATOM   695  N  N   . LYS A 1 95  ? 91.700  92.539  67.288  1.00 110.00 ? 95  LYS A N   1 
ATOM   696  C  CA  . LYS A 1 95  ? 91.575  91.808  66.033  1.00 110.00 ? 95  LYS A CA  1 
ATOM   697  C  C   . LYS A 1 95  ? 90.246  92.059  65.331  1.00 110.00 ? 95  LYS A C   1 
ATOM   698  O  O   . LYS A 1 95  ? 90.141  91.801  64.128  1.00 110.00 ? 95  LYS A O   1 
ATOM   699  C  CB  . LYS A 1 95  ? 91.756  90.309  66.283  1.00 110.00 ? 95  LYS A CB  1 
ATOM   700  C  CG  . LYS A 1 95  ? 92.991  89.963  67.100  1.00 110.00 ? 95  LYS A CG  1 
ATOM   701  C  CD  . LYS A 1 95  ? 94.249  90.560  66.487  1.00 110.00 ? 95  LYS A CD  1 
ATOM   702  C  CE  . LYS A 1 95  ? 95.473  90.272  67.341  1.00 110.00 ? 95  LYS A CE  1 
ATOM   703  N  NZ  . LYS A 1 95  ? 95.877  88.841  67.275  1.00 110.00 ? 95  LYS A NZ  1 
ATOM   704  N  N   . ASP A 1 96  ? 89.233  92.553  66.046  1.00 110.53 ? 96  ASP A N   1 
ATOM   705  C  CA  . ASP A 1 96  ? 87.922  92.785  65.452  1.00 110.53 ? 96  ASP A CA  1 
ATOM   706  C  C   . ASP A 1 96  ? 87.350  94.157  65.791  1.00 110.53 ? 96  ASP A C   1 
ATOM   707  O  O   . ASP A 1 96  ? 86.161  94.393  65.547  1.00 110.53 ? 96  ASP A O   1 
ATOM   708  C  CB  . ASP A 1 96  ? 86.938  91.691  65.882  1.00 110.53 ? 96  ASP A CB  1 
ATOM   709  C  CG  . ASP A 1 96  ? 87.020  91.383  67.363  1.00 110.53 ? 96  ASP A CG  1 
ATOM   710  O  OD1 . ASP A 1 96  ? 87.895  91.959  68.043  1.00 110.53 ? 96  ASP A OD1 1 
ATOM   711  O  OD2 . ASP A 1 96  ? 86.209  90.566  67.847  1.00 110.53 ? 96  ASP A OD2 1 
ATOM   712  N  N   . GLY A 1 97  ? 88.155  95.063  66.341  1.00 105.52 ? 97  GLY A N   1 
ATOM   713  C  CA  . GLY A 1 97  ? 87.678  96.400  66.631  1.00 105.52 ? 97  GLY A CA  1 
ATOM   714  C  C   . GLY A 1 97  ? 86.641  96.488  67.726  1.00 105.52 ? 97  GLY A C   1 
ATOM   715  O  O   . GLY A 1 97  ? 85.882  97.459  67.769  1.00 105.52 ? 97  GLY A O   1 
ATOM   716  N  N   . ASN A 1 98  ? 86.583  95.497  68.619  1.00 111.78 ? 98  ASN A N   1 
ATOM   717  C  CA  . ASN A 1 98  ? 85.610  95.540  69.705  1.00 111.78 ? 98  ASN A CA  1 
ATOM   718  C  C   . ASN A 1 98  ? 85.962  96.604  70.737  1.00 111.78 ? 98  ASN A C   1 
ATOM   719  O  O   . ASN A 1 98  ? 85.063  97.234  71.306  1.00 111.78 ? 98  ASN A O   1 
ATOM   720  C  CB  . ASN A 1 98  ? 85.504  94.168  70.372  1.00 111.78 ? 98  ASN A CB  1 
ATOM   721  C  CG  . ASN A 1 98  ? 86.841  93.655  70.873  1.00 111.78 ? 98  ASN A CG  1 
ATOM   722  O  OD1 . ASN A 1 98  ? 87.419  94.203  71.811  1.00 111.78 ? 98  ASN A OD1 1 
ATOM   723  N  ND2 . ASN A 1 98  ? 87.339  92.594  70.249  1.00 111.78 ? 98  ASN A ND2 1 
ATOM   724  N  N   . GLY A 1 99  ? 87.251  96.819  70.991  1.00 111.49 ? 99  GLY A N   1 
ATOM   725  C  CA  . GLY A 1 99  ? 87.676  97.755  72.010  1.00 111.49 ? 99  GLY A CA  1 
ATOM   726  C  C   . GLY A 1 99  ? 87.648  97.217  73.421  1.00 111.49 ? 99  GLY A C   1 
ATOM   727  O  O   . GLY A 1 99  ? 87.879  97.983  74.363  1.00 111.49 ? 99  GLY A O   1 
ATOM   728  N  N   . PHE A 1 100 ? 87.386  95.924  73.597  1.00 120.68 ? 100 PHE A N   1 
ATOM   729  C  CA  . PHE A 1 100 ? 87.246  95.334  74.922  1.00 120.68 ? 100 PHE A CA  1 
ATOM   730  C  C   . PHE A 1 100 ? 88.187  94.144  75.065  1.00 120.68 ? 100 PHE A C   1 
ATOM   731  O  O   . PHE A 1 100 ? 87.760  93.054  75.462  1.00 120.68 ? 100 PHE A O   1 
ATOM   732  C  CB  . PHE A 1 100 ? 85.797  94.908  75.167  1.00 120.68 ? 100 PHE A CB  1 
ATOM   733  C  CG  . PHE A 1 100 ? 85.385  94.948  76.612  1.00 120.68 ? 100 PHE A CG  1 
ATOM   734  C  CD1 . PHE A 1 100 ? 86.291  95.303  77.598  1.00 120.68 ? 100 PHE A CD1 1 
ATOM   735  C  CD2 . PHE A 1 100 ? 84.089  94.629  76.983  1.00 120.68 ? 100 PHE A CD2 1 
ATOM   736  C  CE1 . PHE A 1 100 ? 85.910  95.343  78.926  1.00 120.68 ? 100 PHE A CE1 1 
ATOM   737  C  CE2 . PHE A 1 100 ? 83.704  94.664  78.309  1.00 120.68 ? 100 PHE A CE2 1 
ATOM   738  C  CZ  . PHE A 1 100 ? 84.615  95.021  79.282  1.00 120.68 ? 100 PHE A CZ  1 
ATOM   739  N  N   . ILE A 1 101 ? 89.462  94.345  74.718  1.00 120.09 ? 101 ILE A N   1 
ATOM   740  C  CA  . ILE A 1 101 ? 90.434  93.256  74.707  1.00 120.09 ? 101 ILE A CA  1 
ATOM   741  C  C   . ILE A 1 101 ? 90.492  92.593  76.076  1.00 120.09 ? 101 ILE A C   1 
ATOM   742  O  O   . ILE A 1 101 ? 90.582  93.266  77.110  1.00 120.09 ? 101 ILE A O   1 
ATOM   743  C  CB  . ILE A 1 101 ? 91.814  93.781  74.285  1.00 120.09 ? 101 ILE A CB  1 
ATOM   744  C  CG1 . ILE A 1 101 ? 92.312  94.840  75.271  1.00 120.09 ? 101 ILE A CG1 1 
ATOM   745  C  CG2 . ILE A 1 101 ? 91.766  94.349  72.879  1.00 120.09 ? 101 ILE A CG2 1 
ATOM   746  C  CD1 . ILE A 1 101 ? 93.753  95.253  75.051  1.00 120.09 ? 101 ILE A CD1 1 
ATOM   747  N  N   . SER A 1 102 ? 90.440  91.263  76.085  1.00 122.84 ? 102 SER A N   1 
ATOM   748  C  CA  . SER A 1 102 ? 90.431  90.518  77.333  1.00 122.84 ? 102 SER A CA  1 
ATOM   749  C  C   . SER A 1 102 ? 91.832  90.450  77.933  1.00 122.84 ? 102 SER A C   1 
ATOM   750  O  O   . SER A 1 102 ? 92.838  90.727  77.275  1.00 122.84 ? 102 SER A O   1 
ATOM   751  C  CB  . SER A 1 102 ? 89.874  89.109  77.122  1.00 122.84 ? 102 SER A CB  1 
ATOM   752  O  OG  . SER A 1 102 ? 90.816  88.269  76.482  1.00 122.84 ? 102 SER A OG  1 
ATOM   753  N  N   . ALA A 1 103 ? 91.883  90.069  79.211  1.00 120.03 ? 103 ALA A N   1 
ATOM   754  C  CA  . ALA A 1 103 ? 93.132  90.107  79.963  1.00 120.03 ? 103 ALA A CA  1 
ATOM   755  C  C   . ALA A 1 103 ? 94.083  88.976  79.593  1.00 120.03 ? 103 ALA A C   1 
ATOM   756  O  O   . ALA A 1 103 ? 95.301  89.131  79.742  1.00 120.03 ? 103 ALA A O   1 
ATOM   757  C  CB  . ALA A 1 103 ? 92.837  90.064  81.463  1.00 120.03 ? 103 ALA A CB  1 
ATOM   758  N  N   . ALA A 1 104 ? 93.560  87.840  79.125  1.00 118.94 ? 104 ALA A N   1 
ATOM   759  C  CA  . ALA A 1 104 ? 94.410  86.673  78.903  1.00 118.94 ? 104 ALA A CA  1 
ATOM   760  C  C   . ALA A 1 104 ? 95.458  86.941  77.828  1.00 118.94 ? 104 ALA A C   1 
ATOM   761  O  O   . ALA A 1 104 ? 96.661  86.772  78.061  1.00 118.94 ? 104 ALA A O   1 
ATOM   762  C  CB  . ALA A 1 104 ? 93.550  85.465  78.528  1.00 118.94 ? 104 ALA A CB  1 
ATOM   763  N  N   . GLU A 1 105 ? 95.023  87.392  76.649  1.00 121.22 ? 105 GLU A N   1 
ATOM   764  C  CA  . GLU A 1 105 ? 95.982  87.648  75.580  1.00 121.22 ? 105 GLU A CA  1 
ATOM   765  C  C   . GLU A 1 105 ? 96.825  88.883  75.867  1.00 121.22 ? 105 GLU A C   1 
ATOM   766  O  O   . GLU A 1 105 ? 97.983  88.949  75.440  1.00 121.22 ? 105 GLU A O   1 
ATOM   767  C  CB  . GLU A 1 105 ? 95.262  87.780  74.236  1.00 121.22 ? 105 GLU A CB  1 
ATOM   768  C  CG  . GLU A 1 105 ? 94.420  89.033  74.076  1.00 121.22 ? 105 GLU A CG  1 
ATOM   769  C  CD  . GLU A 1 105 ? 93.007  88.847  74.586  1.00 121.22 ? 105 GLU A CD  1 
ATOM   770  O  OE1 . GLU A 1 105 ? 92.800  87.989  75.469  1.00 121.22 ? 105 GLU A OE1 1 
ATOM   771  O  OE2 . GLU A 1 105 ? 92.097  89.549  74.098  1.00 121.22 ? 105 GLU A OE2 1 
ATOM   772  N  N   . LEU A 1 106 ? 96.274  89.859  76.594  1.00 123.91 ? 106 LEU A N   1 
ATOM   773  C  CA  . LEU A 1 106 ? 97.059  91.029  76.977  1.00 123.91 ? 106 LEU A CA  1 
ATOM   774  C  C   . LEU A 1 106 ? 98.225  90.635  77.874  1.00 123.91 ? 106 LEU A C   1 
ATOM   775  O  O   . LEU A 1 106 ? 99.341  91.143  77.716  1.00 123.91 ? 106 LEU A O   1 
ATOM   776  C  CB  . LEU A 1 106 ? 96.167  92.056  77.674  1.00 123.91 ? 106 LEU A CB  1 
ATOM   777  C  CG  . LEU A 1 106 ? 95.327  92.953  76.763  1.00 123.91 ? 106 LEU A CG  1 
ATOM   778  C  CD1 . LEU A 1 106 ? 94.285  93.712  77.568  1.00 123.91 ? 106 LEU A CD1 1 
ATOM   779  C  CD2 . LEU A 1 106 ? 96.218  93.914  75.992  1.00 123.91 ? 106 LEU A CD2 1 
ATOM   780  N  N   . ARG A 1 107 ? 97.983  89.739  78.832  1.00 124.99 ? 107 ARG A N   1 
ATOM   781  C  CA  . ARG A 1 107 ? 99.075  89.213  79.642  1.00 124.99 ? 107 ARG A CA  1 
ATOM   782  C  C   . ARG A 1 107 ? 100.015 88.357  78.803  1.00 124.99 ? 107 ARG A C   1 
ATOM   783  O  O   . ARG A 1 107 ? 101.238 88.408  78.979  1.00 124.99 ? 107 ARG A O   1 
ATOM   784  C  CB  . ARG A 1 107 ? 98.517  88.408  80.816  1.00 124.99 ? 107 ARG A CB  1 
ATOM   785  C  CG  . ARG A 1 107 ? 99.575  87.690  81.641  1.00 124.99 ? 107 ARG A CG  1 
ATOM   786  C  CD  . ARG A 1 107 ? 98.982  87.094  82.908  1.00 124.99 ? 107 ARG A CD  1 
ATOM   787  N  NE  . ARG A 1 107 ? 99.865  87.261  84.056  1.00 124.99 ? 107 ARG A NE  1 
ATOM   788  C  CZ  . ARG A 1 107 ? 99.450  87.370  85.311  1.00 124.99 ? 107 ARG A CZ  1 
ATOM   789  N  NH1 . ARG A 1 107 ? 98.164  87.333  85.620  1.00 124.99 ? 107 ARG A NH1 1 
ATOM   790  N  NH2 . ARG A 1 107 ? 100.348 87.519  86.281  1.00 124.99 ? 107 ARG A NH2 1 
ATOM   791  N  N   . HIS A 1 108 ? 99.461  87.566  77.880  1.00 128.13 ? 108 HIS A N   1 
ATOM   792  C  CA  . HIS A 1 108 ? 100.279 86.635  77.108  1.00 128.13 ? 108 HIS A CA  1 
ATOM   793  C  C   . HIS A 1 108 ? 101.270 87.360  76.203  1.00 128.13 ? 108 HIS A C   1 
ATOM   794  O  O   . HIS A 1 108 ? 102.424 86.934  76.078  1.00 128.13 ? 108 HIS A O   1 
ATOM   795  C  CB  . HIS A 1 108 ? 99.379  85.713  76.285  1.00 128.13 ? 108 HIS A CB  1 
ATOM   796  C  CG  . HIS A 1 108 ? 99.942  85.352  74.946  1.00 128.13 ? 108 HIS A CG  1 
ATOM   797  N  ND1 . HIS A 1 108 ? 101.117 84.646  74.797  1.00 128.13 ? 108 HIS A ND1 1 
ATOM   798  C  CD2 . HIS A 1 108 ? 99.493  85.603  73.693  1.00 128.13 ? 108 HIS A CD2 1 
ATOM   799  C  CE1 . HIS A 1 108 ? 101.366 84.476  73.511  1.00 128.13 ? 108 HIS A CE1 1 
ATOM   800  N  NE2 . HIS A 1 108 ? 100.396 85.047  72.819  1.00 128.13 ? 108 HIS A NE2 1 
ATOM   801  N  N   . VAL A 1 109 ? 100.844 88.449  75.560  1.00 128.03 ? 109 VAL A N   1 
ATOM   802  C  CA  . VAL A 1 109 ? 101.649 89.033  74.487  1.00 128.03 ? 109 VAL A CA  1 
ATOM   803  C  C   . VAL A 1 109 ? 102.934 89.642  75.041  1.00 128.03 ? 109 VAL A C   1 
ATOM   804  O  O   . VAL A 1 109 ? 104.040 89.272  74.632  1.00 128.03 ? 109 VAL A O   1 
ATOM   805  C  CB  . VAL A 1 109 ? 100.834 90.065  73.684  1.00 128.03 ? 109 VAL A CB  1 
ATOM   806  C  CG1 . VAL A 1 109 ? 100.083 91.025  74.600  1.00 128.03 ? 109 VAL A CG1 1 
ATOM   807  C  CG2 . VAL A 1 109 ? 101.744 90.830  72.736  1.00 128.03 ? 109 VAL A CG2 1 
ATOM   808  N  N   . MET A 1 110 ? 102.812 90.568  75.989  1.00 128.71 ? 110 MET A N   1 
ATOM   809  C  CA  . MET A 1 110 ? 103.962 91.348  76.428  1.00 128.71 ? 110 MET A CA  1 
ATOM   810  C  C   . MET A 1 110 ? 104.766 90.673  77.532  1.00 128.71 ? 110 MET A C   1 
ATOM   811  O  O   . MET A 1 110 ? 105.801 91.213  77.936  1.00 128.71 ? 110 MET A O   1 
ATOM   812  C  CB  . MET A 1 110 ? 103.504 92.737  76.874  1.00 128.71 ? 110 MET A CB  1 
ATOM   813  C  CG  . MET A 1 110 ? 102.302 92.734  77.794  1.00 128.71 ? 110 MET A CG  1 
ATOM   814  S  SD  . MET A 1 110 ? 101.700 94.403  78.107  1.00 128.71 ? 110 MET A SD  1 
ATOM   815  C  CE  . MET A 1 110 ? 102.334 95.272  76.675  1.00 128.71 ? 110 MET A CE  1 
ATOM   816  N  N   . THR A 1 111 ? 104.326 89.518  78.028  1.00 132.19 ? 111 THR A N   1 
ATOM   817  C  CA  . THR A 1 111 ? 105.170 88.692  78.879  1.00 132.19 ? 111 THR A CA  1 
ATOM   818  C  C   . THR A 1 111 ? 106.038 87.729  78.082  1.00 132.19 ? 111 THR A C   1 
ATOM   819  O  O   . THR A 1 111 ? 106.922 87.090  78.662  1.00 132.19 ? 111 THR A O   1 
ATOM   820  C  CB  . THR A 1 111 ? 104.320 87.899  79.876  1.00 132.19 ? 111 THR A CB  1 
ATOM   821  O  OG1 . THR A 1 111 ? 103.254 87.238  79.182  1.00 132.19 ? 111 THR A OG1 1 
ATOM   822  C  CG2 . THR A 1 111 ? 103.743 88.820  80.936  1.00 132.19 ? 111 THR A CG2 1 
ATOM   823  N  N   . ASN A 1 112 ? 105.801 87.602  76.779  1.00 134.21 ? 112 ASN A N   1 
ATOM   824  C  CA  . ASN A 1 112 ? 106.598 86.752  75.904  1.00 134.21 ? 112 ASN A CA  1 
ATOM   825  C  C   . ASN A 1 112 ? 107.181 87.495  74.713  1.00 134.21 ? 112 ASN A C   1 
ATOM   826  O  O   . ASN A 1 112 ? 108.338 87.261  74.355  1.00 134.21 ? 112 ASN A O   1 
ATOM   827  C  CB  . ASN A 1 112 ? 105.750 85.575  75.402  1.00 134.21 ? 112 ASN A CB  1 
ATOM   828  C  CG  . ASN A 1 112 ? 105.241 84.701  76.532  1.00 134.21 ? 112 ASN A CG  1 
ATOM   829  O  OD1 . ASN A 1 112 ? 105.957 83.835  77.033  1.00 134.21 ? 112 ASN A OD1 1 
ATOM   830  N  ND2 . ASN A 1 112 ? 103.998 84.928  76.940  1.00 134.21 ? 112 ASN A ND2 1 
ATOM   831  N  N   . LEU A 1 113 ? 106.415 88.387  74.092  1.00 130.20 ? 113 LEU A N   1 
ATOM   832  C  CA  . LEU A 1 113 ? 106.883 89.108  72.920  1.00 130.20 ? 113 LEU A CA  1 
ATOM   833  C  C   . LEU A 1 113 ? 107.625 90.377  73.327  1.00 130.20 ? 113 LEU A C   1 
ATOM   834  O  O   . LEU A 1 113 ? 107.558 90.829  74.473  1.00 130.20 ? 113 LEU A O   1 
ATOM   835  C  CB  . LEU A 1 113 ? 105.714 89.464  72.000  1.00 130.20 ? 113 LEU A CB  1 
ATOM   836  C  CG  . LEU A 1 113 ? 105.235 88.402  71.008  1.00 130.20 ? 113 LEU A CG  1 
ATOM   837  C  CD1 . LEU A 1 113 ? 104.395 87.344  71.705  1.00 130.20 ? 113 LEU A CD1 1 
ATOM   838  C  CD2 . LEU A 1 113 ? 104.449 89.052  69.882  1.00 130.20 ? 113 LEU A CD2 1 
ATOM   839  N  N   . GLY A 1 114 ? 108.330 90.956  72.359  1.00 131.57 ? 114 GLY A N   1 
ATOM   840  C  CA  . GLY A 1 114 ? 109.077 92.177  72.623  1.00 131.57 ? 114 GLY A CA  1 
ATOM   841  C  C   . GLY A 1 114 ? 110.128 91.948  73.689  1.00 131.57 ? 114 GLY A C   1 
ATOM   842  O  O   . GLY A 1 114 ? 110.893 90.979  73.642  1.00 131.57 ? 114 GLY A O   1 
ATOM   843  N  N   . GLU A 1 115 ? 110.171 92.848  74.666  1.00 122.81 ? 115 GLU A N   1 
ATOM   844  C  CA  . GLU A 1 115 ? 111.084 92.747  75.801  1.00 122.81 ? 115 GLU A CA  1 
ATOM   845  C  C   . GLU A 1 115 ? 110.231 92.454  77.034  1.00 122.81 ? 115 GLU A C   1 
ATOM   846  O  O   . GLU A 1 115 ? 109.543 93.331  77.557  1.00 122.81 ? 115 GLU A O   1 
ATOM   847  C  CB  . GLU A 1 115 ? 111.907 94.020  75.958  1.00 122.81 ? 115 GLU A CB  1 
ATOM   848  C  CG  . GLU A 1 115 ? 113.305 93.942  75.347  1.00 122.81 ? 115 GLU A CG  1 
ATOM   849  C  CD  . GLU A 1 115 ? 113.980 92.589  75.526  1.00 122.81 ? 115 GLU A CD  1 
ATOM   850  O  OE1 . GLU A 1 115 ? 113.914 92.018  76.636  1.00 122.81 ? 115 GLU A OE1 1 
ATOM   851  O  OE2 . GLU A 1 115 ? 114.581 92.096  74.549  1.00 122.81 ? 115 GLU A OE2 1 
ATOM   852  N  N   . LYS A 1 116 ? 110.289 91.207  77.494  1.00 124.99 ? 116 LYS A N   1 
ATOM   853  C  CA  . LYS A 1 116 ? 109.368 90.730  78.517  1.00 124.99 ? 116 LYS A CA  1 
ATOM   854  C  C   . LYS A 1 116 ? 109.590 91.446  79.845  1.00 124.99 ? 116 LYS A C   1 
ATOM   855  O  O   . LYS A 1 116 ? 110.723 91.726  80.248  1.00 124.99 ? 116 LYS A O   1 
ATOM   856  C  CB  . LYS A 1 116 ? 109.534 89.222  78.706  1.00 124.99 ? 116 LYS A CB  1 
ATOM   857  C  CG  . LYS A 1 116 ? 109.533 88.435  77.408  1.00 124.99 ? 116 LYS A CG  1 
ATOM   858  C  CD  . LYS A 1 116 ? 110.117 87.047  77.609  1.00 124.99 ? 116 LYS A CD  1 
ATOM   859  C  CE  . LYS A 1 116 ? 111.587 87.120  77.989  1.00 124.99 ? 116 LYS A CE  1 
ATOM   860  N  NZ  . LYS A 1 116 ? 112.454 87.406  76.812  1.00 124.99 ? 116 LYS A NZ  1 
ATOM   861  N  N   . LEU A 1 117 ? 108.484 91.744  80.523  1.00 117.91 ? 117 LEU A N   1 
ATOM   862  C  CA  . LEU A 1 117 ? 108.538 92.289  81.872  1.00 117.91 ? 117 LEU A CA  1 
ATOM   863  C  C   . LEU A 1 117 ? 108.512 91.165  82.897  1.00 117.91 ? 117 LEU A C   1 
ATOM   864  O  O   . LEU A 1 117 ? 108.328 89.994  82.555  1.00 117.91 ? 117 LEU A O   1 
ATOM   865  C  CB  . LEU A 1 117 ? 107.366 93.238  82.123  1.00 117.91 ? 117 LEU A CB  1 
ATOM   866  C  CG  . LEU A 1 117 ? 106.834 94.088  80.969  1.00 117.91 ? 117 LEU A CG  1 
ATOM   867  C  CD1 . LEU A 1 117 ? 105.744 95.018  81.467  1.00 117.91 ? 117 LEU A CD1 1 
ATOM   868  C  CD2 . LEU A 1 117 ? 107.969 94.899  80.375  1.00 117.91 ? 117 LEU A CD2 1 
ATOM   869  N  N   . THR A 1 118 ? 108.697 91.530  84.162  1.00 127.88 ? 118 THR A N   1 
ATOM   870  C  CA  . THR A 1 118 ? 108.593 90.565  85.241  1.00 127.88 ? 118 THR A CA  1 
ATOM   871  C  C   . THR A 1 118 ? 107.127 90.344  85.611  1.00 127.88 ? 118 THR A C   1 
ATOM   872  O  O   . THR A 1 118 ? 106.214 90.955  85.049  1.00 127.88 ? 118 THR A O   1 
ATOM   873  C  CB  . THR A 1 118 ? 109.388 91.030  86.460  1.00 127.88 ? 118 THR A CB  1 
ATOM   874  O  OG1 . THR A 1 118 ? 108.873 92.285  86.918  1.00 127.88 ? 118 THR A OG1 1 
ATOM   875  C  CG2 . THR A 1 118 ? 110.858 91.195  86.101  1.00 127.88 ? 118 THR A CG2 1 
ATOM   876  N  N   . ASP A 1 119 ? 106.907 89.450  86.576  1.00 131.11 ? 119 ASP A N   1 
ATOM   877  C  CA  . ASP A 1 119 ? 105.543 89.112  86.970  1.00 131.11 ? 119 ASP A CA  1 
ATOM   878  C  C   . ASP A 1 119 ? 104.876 90.256  87.725  1.00 131.11 ? 119 ASP A C   1 
ATOM   879  O  O   . ASP A 1 119 ? 103.665 90.466  87.597  1.00 131.11 ? 119 ASP A O   1 
ATOM   880  C  CB  . ASP A 1 119 ? 105.544 87.837  87.812  1.00 131.11 ? 119 ASP A CB  1 
ATOM   881  C  CG  . ASP A 1 119 ? 106.331 86.713  87.166  1.00 131.11 ? 119 ASP A CG  1 
ATOM   882  O  OD1 . ASP A 1 119 ? 107.571 86.829  87.077  1.00 131.11 ? 119 ASP A OD1 1 
ATOM   883  O  OD2 . ASP A 1 119 ? 105.709 85.715  86.746  1.00 131.11 ? 119 ASP A OD2 1 
ATOM   884  N  N   . GLU A 1 120 ? 105.647 91.003  88.519  1.00 128.17 ? 120 GLU A N   1 
ATOM   885  C  CA  . GLU A 1 120 ? 105.063 92.058  89.344  1.00 128.17 ? 120 GLU A CA  1 
ATOM   886  C  C   . GLU A 1 120 ? 104.453 93.165  88.490  1.00 128.17 ? 120 GLU A C   1 
ATOM   887  O  O   . GLU A 1 120 ? 103.374 93.683  88.808  1.00 128.17 ? 120 GLU A O   1 
ATOM   888  C  CB  . GLU A 1 120 ? 106.122 92.630  90.286  1.00 128.17 ? 120 GLU A CB  1 
ATOM   889  C  CG  . GLU A 1 120 ? 106.668 91.628  91.292  1.00 128.17 ? 120 GLU A CG  1 
ATOM   890  C  CD  . GLU A 1 120 ? 107.878 90.875  90.772  1.00 128.17 ? 120 GLU A CD  1 
ATOM   891  O  OE1 . GLU A 1 120 ? 108.109 90.888  89.545  1.00 128.17 ? 120 GLU A OE1 1 
ATOM   892  O  OE2 . GLU A 1 120 ? 108.599 90.269  91.592  1.00 128.17 ? 120 GLU A OE2 1 
ATOM   893  N  N   . GLU A 1 121 ? 105.136 93.548  87.408  1.00 119.54 ? 121 GLU A N   1 
ATOM   894  C  CA  . GLU A 1 121 ? 104.644 94.631  86.562  1.00 119.54 ? 121 GLU A CA  1 
ATOM   895  C  C   . GLU A 1 121 ? 103.290 94.287  85.954  1.00 119.54 ? 121 GLU A C   1 
ATOM   896  O  O   . GLU A 1 121 ? 102.346 95.081  86.030  1.00 119.54 ? 121 GLU A O   1 
ATOM   897  C  CB  . GLU A 1 121 ? 105.662 94.945  85.465  1.00 119.54 ? 121 GLU A CB  1 
ATOM   898  C  CG  . GLU A 1 121 ? 106.732 95.949  85.869  1.00 119.54 ? 121 GLU A CG  1 
ATOM   899  C  CD  . GLU A 1 121 ? 107.624 95.444  86.984  1.00 119.54 ? 121 GLU A CD  1 
ATOM   900  O  OE1 . GLU A 1 121 ? 107.816 94.214  87.084  1.00 119.54 ? 121 GLU A OE1 1 
ATOM   901  O  OE2 . GLU A 1 121 ? 108.135 96.277  87.761  1.00 119.54 ? 121 GLU A OE2 1 
ATOM   902  N  N   . VAL A 1 122 ? 103.171 93.101  85.355  1.00 117.81 ? 122 VAL A N   1 
ATOM   903  C  CA  . VAL A 1 122 ? 101.900 92.711  84.753  1.00 117.81 ? 122 VAL A CA  1 
ATOM   904  C  C   . VAL A 1 122 ? 100.845 92.485  85.828  1.00 117.81 ? 122 VAL A C   1 
ATOM   905  O  O   . VAL A 1 122 ? 99.664  92.795  85.630  1.00 117.81 ? 122 VAL A O   1 
ATOM   906  C  CB  . VAL A 1 122 ? 102.082 91.472  83.857  1.00 117.81 ? 122 VAL A CB  1 
ATOM   907  C  CG1 . VAL A 1 122 ? 102.605 91.888  82.491  1.00 117.81 ? 122 VAL A CG1 1 
ATOM   908  C  CG2 . VAL A 1 122 ? 103.020 90.474  84.506  1.00 117.81 ? 122 VAL A CG2 1 
ATOM   909  N  N   . ASP A 1 123 ? 101.243 91.942  86.982  1.00 119.59 ? 123 ASP A N   1 
ATOM   910  C  CA  . ASP A 1 123 ? 100.297 91.800  88.083  1.00 119.59 ? 123 ASP A CA  1 
ATOM   911  C  C   . ASP A 1 123 ? 99.657  93.141  88.415  1.00 119.59 ? 123 ASP A C   1 
ATOM   912  O  O   . ASP A 1 123 ? 98.428  93.270  88.429  1.00 119.59 ? 123 ASP A O   1 
ATOM   913  C  CB  . ASP A 1 123 ? 100.997 91.217  89.312  1.00 119.59 ? 123 ASP A CB  1 
ATOM   914  C  CG  . ASP A 1 123 ? 101.267 89.732  89.180  1.00 119.59 ? 123 ASP A CG  1 
ATOM   915  O  OD1 . ASP A 1 123 ? 100.677 89.096  88.280  1.00 119.59 ? 123 ASP A OD1 1 
ATOM   916  O  OD2 . ASP A 1 123 ? 102.069 89.201  89.976  1.00 119.59 ? 123 ASP A OD2 1 
ATOM   917  N  N   . GLU A 1 124 ? 100.483 94.167  88.629  1.00 107.50 ? 124 GLU A N   1 
ATOM   918  C  CA  . GLU A 1 124 ? 99.953  95.495  88.925  1.00 107.50 ? 124 GLU A CA  1 
ATOM   919  C  C   . GLU A 1 124 ? 99.135  96.043  87.759  1.00 107.50 ? 124 GLU A C   1 
ATOM   920  O  O   . GLU A 1 124 ? 98.090  96.674  87.965  1.00 107.50 ? 124 GLU A O   1 
ATOM   921  C  CB  . GLU A 1 124 ? 101.096 96.449  89.271  1.00 107.50 ? 124 GLU A CB  1 
ATOM   922  C  CG  . GLU A 1 124 ? 100.642 97.796  89.813  1.00 107.50 ? 124 GLU A CG  1 
ATOM   923  C  CD  . GLU A 1 124 ? 100.269 97.742  91.281  1.00 107.50 ? 124 GLU A CD  1 
ATOM   924  O  OE1 . GLU A 1 124 ? 99.138  97.313  91.594  1.00 107.50 ? 124 GLU A OE1 1 
ATOM   925  O  OE2 . GLU A 1 124 ? 101.105 98.132  92.123  1.00 107.50 ? 124 GLU A OE2 1 
ATOM   926  N  N   . MET A 1 125 ? 99.591  95.808  86.527  1.00 108.21 ? 125 MET A N   1 
ATOM   927  C  CA  . MET A 1 125 ? 98.951  96.415  85.364  1.00 108.21 ? 125 MET A CA  1 
ATOM   928  C  C   . MET A 1 125 ? 97.542  95.872  85.151  1.00 108.21 ? 125 MET A C   1 
ATOM   929  O  O   . MET A 1 125 ? 96.586  96.640  84.999  1.00 108.21 ? 125 MET A O   1 
ATOM   930  C  CB  . MET A 1 125 ? 99.818  96.193  84.125  1.00 108.21 ? 125 MET A CB  1 
ATOM   931  C  CG  . MET A 1 125 ? 99.087  96.352  82.808  1.00 108.21 ? 125 MET A CG  1 
ATOM   932  S  SD  . MET A 1 125 ? 100.208 96.930  81.525  1.00 108.21 ? 125 MET A SD  1 
ATOM   933  C  CE  . MET A 1 125 ? 101.267 95.498  81.362  1.00 108.21 ? 125 MET A CE  1 
ATOM   934  N  N   . ILE A 1 126 ? 97.389  94.548  85.139  1.00 110.75 ? 126 ILE A N   1 
ATOM   935  C  CA  . ILE A 1 126 ? 96.069  93.961  84.927  1.00 110.75 ? 126 ILE A CA  1 
ATOM   936  C  C   . ILE A 1 126 ? 95.358  93.805  86.272  1.00 110.75 ? 126 ILE A C   1 
ATOM   937  O  O   . ILE A 1 126 ? 94.258  93.247  86.350  1.00 110.75 ? 126 ILE A O   1 
ATOM   938  C  CB  . ILE A 1 126 ? 96.149  92.633  84.140  1.00 110.75 ? 126 ILE A CB  1 
ATOM   939  C  CG1 . ILE A 1 126 ? 97.008  92.791  82.883  1.00 110.75 ? 126 ILE A CG1 1 
ATOM   940  C  CG2 . ILE A 1 126 ? 94.777  92.179  83.670  1.00 110.75 ? 126 ILE A CG2 1 
ATOM   941  C  CD1 . ILE A 1 126 ? 98.422  92.300  82.986  1.00 110.75 ? 126 ILE A CD1 1 
ATOM   942  N  N   . ARG A 1 127 ? 95.960  94.326  87.341  1.00 114.50 ? 127 ARG A N   1 
ATOM   943  C  CA  . ARG A 1 127 ? 95.186  94.553  88.554  1.00 114.50 ? 127 ARG A CA  1 
ATOM   944  C  C   . ARG A 1 127 ? 94.482  95.903  88.509  1.00 114.50 ? 127 ARG A C   1 
ATOM   945  O  O   . ARG A 1 127 ? 93.320  96.019  88.910  1.00 114.50 ? 127 ARG A O   1 
ATOM   946  C  CB  . ARG A 1 127 ? 96.095  94.467  89.784  1.00 114.50 ? 127 ARG A CB  1 
ATOM   947  C  CG  . ARG A 1 127 ? 95.348  94.468  91.108  1.00 114.50 ? 127 ARG A CG  1 
ATOM   948  C  CD  . ARG A 1 127 ? 96.191  95.072  92.221  1.00 114.50 ? 127 ARG A CD  1 
ATOM   949  N  NE  . ARG A 1 127 ? 97.613  94.792  92.063  1.00 114.50 ? 127 ARG A NE  1 
ATOM   950  C  CZ  . ARG A 1 127 ? 98.193  93.642  92.378  1.00 114.50 ? 127 ARG A CZ  1 
ATOM   951  N  NH1 . ARG A 1 127 ? 97.500  92.633  92.877  1.00 114.50 ? 127 ARG A NH1 1 
ATOM   952  N  NH2 . ARG A 1 127 ? 99.501  93.502  92.188  1.00 114.50 ? 127 ARG A NH2 1 
ATOM   953  N  N   . GLU A 1 128 ? 95.181  96.932  88.026  1.00 117.74 ? 128 GLU A N   1 
ATOM   954  C  CA  . GLU A 1 128 ? 94.568  98.251  87.916  1.00 117.74 ? 128 GLU A CA  1 
ATOM   955  C  C   . GLU A 1 128 ? 93.597  98.301  86.741  1.00 117.74 ? 128 GLU A C   1 
ATOM   956  O  O   . GLU A 1 128 ? 92.512  98.885  86.849  1.00 117.74 ? 128 GLU A O   1 
ATOM   957  C  CB  . GLU A 1 128 ? 95.670  99.319  87.812  1.00 117.74 ? 128 GLU A CB  1 
ATOM   958  C  CG  . GLU A 1 128 ? 95.246  100.806 87.725  1.00 117.74 ? 128 GLU A CG  1 
ATOM   959  C  CD  . GLU A 1 128 ? 94.475  101.206 86.474  1.00 117.74 ? 128 GLU A CD  1 
ATOM   960  O  OE1 . GLU A 1 128 ? 93.782  102.244 86.516  1.00 117.74 ? 128 GLU A OE1 1 
ATOM   961  O  OE2 . GLU A 1 128 ? 94.619  100.535 85.431  1.00 117.74 ? 128 GLU A OE2 1 
ATOM   962  N  N   . ALA A 1 129 ? 93.970  97.702  85.609  1.00 115.09 ? 129 ALA A N   1 
ATOM   963  C  CA  . ALA A 1 129 ? 93.167  97.820  84.395  1.00 115.09 ? 129 ALA A CA  1 
ATOM   964  C  C   . ALA A 1 129 ? 91.887  96.995  84.474  1.00 115.09 ? 129 ALA A C   1 
ATOM   965  O  O   . ALA A 1 129 ? 90.808  97.475  84.108  1.00 115.09 ? 129 ALA A O   1 
ATOM   966  C  CB  . ALA A 1 129 ? 93.996  97.407  83.179  1.00 115.09 ? 129 ALA A CB  1 
ATOM   967  N  N   . ASP A 1 130 ? 91.983  95.754  84.951  1.00 127.88 ? 130 ASP A N   1 
ATOM   968  C  CA  . ASP A 1 130 ? 90.832  94.850  84.977  1.00 127.88 ? 130 ASP A CA  1 
ATOM   969  C  C   . ASP A 1 130 ? 90.015  95.090  86.248  1.00 127.88 ? 130 ASP A C   1 
ATOM   970  O  O   . ASP A 1 130 ? 89.982  94.282  87.178  1.00 127.88 ? 130 ASP A O   1 
ATOM   971  C  CB  . ASP A 1 130 ? 91.289  93.401  84.865  1.00 127.88 ? 130 ASP A CB  1 
ATOM   972  C  CG  . ASP A 1 130 ? 90.188  92.477  84.380  1.00 127.88 ? 130 ASP A CG  1 
ATOM   973  O  OD1 . ASP A 1 130 ? 89.349  92.925  83.572  1.00 127.88 ? 130 ASP A OD1 1 
ATOM   974  O  OD2 . ASP A 1 130 ? 90.164  91.303  84.805  1.00 127.88 ? 130 ASP A OD2 1 
ATOM   975  N  N   . ILE A 1 131 ? 89.344  96.243  86.270  1.00 125.29 ? 131 ILE A N   1 
ATOM   976  C  CA  . ILE A 1 131 ? 88.481  96.578  87.399  1.00 125.29 ? 131 ILE A CA  1 
ATOM   977  C  C   . ILE A 1 131 ? 87.305  95.612  87.474  1.00 125.29 ? 131 ILE A C   1 
ATOM   978  O  O   . ILE A 1 131 ? 86.969  95.099  88.549  1.00 125.29 ? 131 ILE A O   1 
ATOM   979  C  CB  . ILE A 1 131 ? 88.010  98.040  87.295  1.00 125.29 ? 131 ILE A CB  1 
ATOM   980  C  CG1 . ILE A 1 131 ? 89.207  98.992  87.344  1.00 125.29 ? 131 ILE A CG1 1 
ATOM   981  C  CG2 . ILE A 1 131 ? 87.022  98.365  88.405  1.00 125.29 ? 131 ILE A CG2 1 
ATOM   982  C  CD1 . ILE A 1 131 ? 88.832  100.454 87.235  1.00 125.29 ? 131 ILE A CD1 1 
ATOM   983  N  N   . ASP A 1 132 ? 86.667  95.345  86.339  1.00 135.11 ? 132 ASP A N   1 
ATOM   984  C  CA  . ASP A 1 132 ? 85.545  94.422  86.294  1.00 135.11 ? 132 ASP A CA  1 
ATOM   985  C  C   . ASP A 1 132 ? 86.028  92.980  86.386  1.00 135.11 ? 132 ASP A C   1 
ATOM   986  O  O   . ASP A 1 132 ? 87.163  92.656  86.026  1.00 135.11 ? 132 ASP A O   1 
ATOM   987  C  CB  . ASP A 1 132 ? 84.737  94.620  85.011  1.00 135.11 ? 132 ASP A CB  1 
ATOM   988  C  CG  . ASP A 1 132 ? 84.093  95.989  84.935  1.00 135.11 ? 132 ASP A CG  1 
ATOM   989  O  OD1 . ASP A 1 132 ? 83.739  96.543  85.997  1.00 135.11 ? 132 ASP A OD1 1 
ATOM   990  O  OD2 . ASP A 1 132 ? 83.940  96.512  83.811  1.00 135.11 ? 132 ASP A OD2 1 
ATOM   991  N  N   . GLY A 1 133 ? 85.148  92.111  86.876  1.00 136.53 ? 133 GLY A N   1 
ATOM   992  C  CA  . GLY A 1 133 ? 85.444  90.699  86.986  1.00 136.53 ? 133 GLY A CA  1 
ATOM   993  C  C   . GLY A 1 133 ? 85.226  89.890  85.731  1.00 136.53 ? 133 GLY A C   1 
ATOM   994  O  O   . GLY A 1 133 ? 85.430  88.673  85.747  1.00 136.53 ? 133 GLY A O   1 
ATOM   995  N  N   . ASP A 1 134 ? 84.813  90.531  84.635  1.00 143.67 ? 134 ASP A N   1 
ATOM   996  C  CA  . ASP A 1 134 ? 84.556  89.809  83.395  1.00 143.67 ? 134 ASP A CA  1 
ATOM   997  C  C   . ASP A 1 134 ? 85.834  89.321  82.726  1.00 143.67 ? 134 ASP A C   1 
ATOM   998  O  O   . ASP A 1 134 ? 85.764  88.473  81.831  1.00 143.67 ? 134 ASP A O   1 
ATOM   999  C  CB  . ASP A 1 134 ? 83.771  90.696  82.426  1.00 143.67 ? 134 ASP A CB  1 
ATOM   1000 C  CG  . ASP A 1 134 ? 82.414  91.097  82.973  1.00 143.67 ? 134 ASP A CG  1 
ATOM   1001 O  OD1 . ASP A 1 134 ? 81.912  90.406  83.884  1.00 143.67 ? 134 ASP A OD1 1 
ATOM   1002 O  OD2 . ASP A 1 134 ? 81.852  92.104  82.493  1.00 143.67 ? 134 ASP A OD2 1 
ATOM   1003 N  N   . GLY A 1 135 ? 86.992  89.831  83.136  1.00 133.15 ? 135 GLY A N   1 
ATOM   1004 C  CA  . GLY A 1 135 ? 88.250  89.445  82.533  1.00 133.15 ? 135 GLY A CA  1 
ATOM   1005 C  C   . GLY A 1 135 ? 88.627  90.203  81.280  1.00 133.15 ? 135 GLY A C   1 
ATOM   1006 O  O   . GLY A 1 135 ? 89.601  89.825  80.619  1.00 133.15 ? 135 GLY A O   1 
ATOM   1007 N  N   . GLN A 1 136 ? 87.892  91.255  80.931  1.00 128.57 ? 136 GLN A N   1 
ATOM   1008 C  CA  . GLN A 1 136 ? 88.178  92.063  79.757  1.00 128.57 ? 136 GLN A CA  1 
ATOM   1009 C  C   . GLN A 1 136 ? 88.471  93.496  80.178  1.00 128.57 ? 136 GLN A C   1 
ATOM   1010 O  O   . GLN A 1 136 ? 87.881  94.014  81.132  1.00 128.57 ? 136 GLN A O   1 
ATOM   1011 C  CB  . GLN A 1 136 ? 87.011  92.032  78.763  1.00 128.57 ? 136 GLN A CB  1 
ATOM   1012 C  CG  . GLN A 1 136 ? 86.745  90.660  78.165  1.00 128.57 ? 136 GLN A CG  1 
ATOM   1013 C  CD  . GLN A 1 136 ? 85.634  90.676  77.135  1.00 128.57 ? 136 GLN A CD  1 
ATOM   1014 O  OE1 . GLN A 1 136 ? 84.515  90.240  77.405  1.00 128.57 ? 136 GLN A OE1 1 
ATOM   1015 N  NE2 . GLN A 1 136 ? 85.938  91.180  75.944  1.00 128.57 ? 136 GLN A NE2 1 
ATOM   1016 N  N   . VAL A 1 137 ? 89.390  94.134  79.458  1.00 122.42 ? 137 VAL A N   1 
ATOM   1017 C  CA  . VAL A 1 137 ? 89.875  95.469  79.789  1.00 122.42 ? 137 VAL A CA  1 
ATOM   1018 C  C   . VAL A 1 137 ? 89.562  96.405  78.632  1.00 122.42 ? 137 VAL A C   1 
ATOM   1019 O  O   . VAL A 1 137 ? 89.883  96.102  77.477  1.00 122.42 ? 137 VAL A O   1 
ATOM   1020 C  CB  . VAL A 1 137 ? 91.385  95.464  80.090  1.00 122.42 ? 137 VAL A CB  1 
ATOM   1021 C  CG1 . VAL A 1 137 ? 91.910  96.887  80.197  1.00 122.42 ? 137 VAL A CG1 1 
ATOM   1022 C  CG2 . VAL A 1 137 ? 91.670  94.684  81.363  1.00 122.42 ? 137 VAL A CG2 1 
ATOM   1023 N  N   . ASN A 1 138 ? 88.938  97.539  78.944  1.00 117.18 ? 138 ASN A N   1 
ATOM   1024 C  CA  . ASN A 1 138 ? 88.687  98.583  77.955  1.00 117.18 ? 138 ASN A CA  1 
ATOM   1025 C  C   . ASN A 1 138 ? 89.940  99.443  77.835  1.00 117.18 ? 138 ASN A C   1 
ATOM   1026 O  O   . ASN A 1 138 ? 90.311  100.146 78.781  1.00 117.18 ? 138 ASN A O   1 
ATOM   1027 C  CB  . ASN A 1 138 ? 87.476  99.419  78.357  1.00 117.18 ? 138 ASN A CB  1 
ATOM   1028 C  CG  . ASN A 1 138 ? 86.642  99.850  77.167  1.00 117.18 ? 138 ASN A CG  1 
ATOM   1029 O  OD1 . ASN A 1 138 ? 86.260  99.031  76.334  1.00 117.18 ? 138 ASN A OD1 1 
ATOM   1030 N  ND2 . ASN A 1 138 ? 86.358  101.145 77.082  1.00 117.18 ? 138 ASN A ND2 1 
ATOM   1031 N  N   . TYR A 1 139 ? 90.596  99.387  76.674  1.00 115.48 ? 139 TYR A N   1 
ATOM   1032 C  CA  . TYR A 1 139 ? 91.868  100.084 76.510  1.00 115.48 ? 139 TYR A CA  1 
ATOM   1033 C  C   . TYR A 1 139 ? 91.696  101.598 76.500  1.00 115.48 ? 139 TYR A C   1 
ATOM   1034 O  O   . TYR A 1 139 ? 92.568  102.320 76.998  1.00 115.48 ? 139 TYR A O   1 
ATOM   1035 C  CB  . TYR A 1 139 ? 92.559  99.622  75.226  1.00 115.48 ? 139 TYR A CB  1 
ATOM   1036 C  CG  . TYR A 1 139 ? 91.958  100.188 73.957  1.00 115.48 ? 139 TYR A CG  1 
ATOM   1037 C  CD1 . TYR A 1 139 ? 90.815  99.634  73.399  1.00 115.48 ? 139 TYR A CD1 1 
ATOM   1038 C  CD2 . TYR A 1 139 ? 92.537  101.277 73.317  1.00 115.48 ? 139 TYR A CD2 1 
ATOM   1039 C  CE1 . TYR A 1 139 ? 90.264  100.148 72.240  1.00 115.48 ? 139 TYR A CE1 1 
ATOM   1040 C  CE2 . TYR A 1 139 ? 91.993  101.797 72.158  1.00 115.48 ? 139 TYR A CE2 1 
ATOM   1041 C  CZ  . TYR A 1 139 ? 90.857  101.229 71.625  1.00 115.48 ? 139 TYR A CZ  1 
ATOM   1042 O  OH  . TYR A 1 139 ? 90.311  101.743 70.471  1.00 115.48 ? 139 TYR A OH  1 
ATOM   1043 N  N   . GLU A 1 140 ? 90.592  102.096 75.936  1.00 110.88 ? 140 GLU A N   1 
ATOM   1044 C  CA  . GLU A 1 140 ? 90.416  103.538 75.793  1.00 110.88 ? 140 GLU A CA  1 
ATOM   1045 C  C   . GLU A 1 140 ? 90.363  104.225 77.152  1.00 110.88 ? 140 GLU A C   1 
ATOM   1046 O  O   . GLU A 1 140 ? 91.088  105.198 77.398  1.00 110.88 ? 140 GLU A O   1 
ATOM   1047 C  CB  . GLU A 1 140 ? 89.149  103.832 74.989  1.00 110.88 ? 140 GLU A CB  1 
ATOM   1048 N  N   . GLU A 1 141 ? 89.509  103.728 78.051  1.00 116.00 ? 141 GLU A N   1 
ATOM   1049 C  CA  . GLU A 1 141 ? 89.420  104.321 79.381  1.00 116.00 ? 141 GLU A CA  1 
ATOM   1050 C  C   . GLU A 1 141 ? 90.723  104.154 80.150  1.00 116.00 ? 141 GLU A C   1 
ATOM   1051 O  O   . GLU A 1 141 ? 91.124  105.058 80.888  1.00 116.00 ? 141 GLU A O   1 
ATOM   1052 C  CB  . GLU A 1 141 ? 88.247  103.718 80.158  1.00 116.00 ? 141 GLU A CB  1 
ATOM   1053 C  CG  . GLU A 1 141 ? 88.323  102.216 80.384  1.00 116.00 ? 141 GLU A CG  1 
ATOM   1054 C  CD  . GLU A 1 141 ? 89.015  101.851 81.684  1.00 116.00 ? 141 GLU A CD  1 
ATOM   1055 O  OE1 . GLU A 1 141 ? 89.036  102.695 82.606  1.00 116.00 ? 141 GLU A OE1 1 
ATOM   1056 O  OE2 . GLU A 1 141 ? 89.538  100.722 81.785  1.00 116.00 ? 141 GLU A OE2 1 
ATOM   1057 N  N   . PHE A 1 142 ? 91.396  103.013 79.980  1.00 110.64 ? 142 PHE A N   1 
ATOM   1058 C  CA  . PHE A 1 142 ? 92.685  102.796 80.629  1.00 110.64 ? 142 PHE A CA  1 
ATOM   1059 C  C   . PHE A 1 142 ? 93.682  103.878 80.230  1.00 110.64 ? 142 PHE A C   1 
ATOM   1060 O  O   . PHE A 1 142 ? 94.296  104.525 81.089  1.00 110.64 ? 142 PHE A O   1 
ATOM   1061 C  CB  . PHE A 1 142 ? 93.211  101.407 80.257  1.00 110.64 ? 142 PHE A CB  1 
ATOM   1062 C  CG  . PHE A 1 142 ? 94.498  101.026 80.938  1.00 110.64 ? 142 PHE A CG  1 
ATOM   1063 C  CD1 . PHE A 1 142 ? 95.297  100.028 80.406  1.00 110.64 ? 142 PHE A CD1 1 
ATOM   1064 C  CD2 . PHE A 1 142 ? 94.893  101.630 82.120  1.00 110.64 ? 142 PHE A CD2 1 
ATOM   1065 C  CE1 . PHE A 1 142 ? 96.478  99.661  81.021  1.00 110.64 ? 142 PHE A CE1 1 
ATOM   1066 C  CE2 . PHE A 1 142 ? 96.072  101.267 82.739  1.00 110.64 ? 142 PHE A CE2 1 
ATOM   1067 C  CZ  . PHE A 1 142 ? 96.865  100.280 82.190  1.00 110.64 ? 142 PHE A CZ  1 
ATOM   1068 N  N   . VAL A 1 143 ? 93.845  104.095 78.923  1.00 108.59 ? 143 VAL A N   1 
ATOM   1069 C  CA  . VAL A 1 143 ? 94.802  105.088 78.448  1.00 108.59 ? 143 VAL A CA  1 
ATOM   1070 C  C   . VAL A 1 143 ? 94.393  106.486 78.894  1.00 108.59 ? 143 VAL A C   1 
ATOM   1071 O  O   . VAL A 1 143 ? 95.234  107.276 79.338  1.00 108.59 ? 143 VAL A O   1 
ATOM   1072 C  CB  . VAL A 1 143 ? 94.953  105.002 76.918  1.00 108.59 ? 143 VAL A CB  1 
ATOM   1073 C  CG1 . VAL A 1 143 ? 95.907  106.075 76.419  1.00 108.59 ? 143 VAL A CG1 1 
ATOM   1074 C  CG2 . VAL A 1 143 ? 95.450  103.625 76.515  1.00 108.59 ? 143 VAL A CG2 1 
ATOM   1075 N  N   . THR A 1 144 ? 93.102  106.816 78.791  1.00 111.57 ? 144 THR A N   1 
ATOM   1076 C  CA  . THR A 1 144 ? 92.665  108.160 79.159  1.00 111.57 ? 144 THR A CA  1 
ATOM   1077 C  C   . THR A 1 144 ? 92.891  108.436 80.641  1.00 111.57 ? 144 THR A C   1 
ATOM   1078 O  O   . THR A 1 144 ? 93.319  109.535 81.014  1.00 111.57 ? 144 THR A O   1 
ATOM   1079 C  CB  . THR A 1 144 ? 91.194  108.364 78.798  1.00 111.57 ? 144 THR A CB  1 
ATOM   1080 O  OG1 . THR A 1 144 ? 90.402  107.331 79.396  1.00 111.57 ? 144 THR A OG1 1 
ATOM   1081 C  CG2 . THR A 1 144 ? 91.005  108.349 77.287  1.00 111.57 ? 144 THR A CG2 1 
ATOM   1082 N  N   . MET A 1 145 ? 92.611  107.456 81.505  1.00 109.65 ? 145 MET A N   1 
ATOM   1083 C  CA  . MET A 1 145 ? 92.754  107.689 82.938  1.00 109.65 ? 145 MET A CA  1 
ATOM   1084 C  C   . MET A 1 145 ? 94.211  107.658 83.381  1.00 109.65 ? 145 MET A C   1 
ATOM   1085 O  O   . MET A 1 145 ? 94.581  108.387 84.309  1.00 109.65 ? 145 MET A O   1 
ATOM   1086 C  CB  . MET A 1 145 ? 91.877  106.693 83.719  1.00 109.65 ? 145 MET A CB  1 
ATOM   1087 C  CG  . MET A 1 145 ? 92.284  105.201 83.807  1.00 109.65 ? 145 MET A CG  1 
ATOM   1088 S  SD  . MET A 1 145 ? 93.946  104.653 84.263  1.00 109.65 ? 145 MET A SD  1 
ATOM   1089 C  CE  . MET A 1 145 ? 94.171  105.467 85.845  1.00 109.65 ? 145 MET A CE  1 
ATOM   1090 N  N   . MET A 1 146 ? 95.053  106.838 82.745  1.00 104.72 ? 146 MET A N   1 
ATOM   1091 C  CA  . MET A 1 146 ? 96.459  106.814 83.133  1.00 104.72 ? 146 MET A CA  1 
ATOM   1092 C  C   . MET A 1 146 ? 97.231  108.011 82.589  1.00 104.72 ? 146 MET A C   1 
ATOM   1093 O  O   . MET A 1 146 ? 98.111  108.537 83.280  1.00 104.72 ? 146 MET A O   1 
ATOM   1094 C  CB  . MET A 1 146 ? 97.106  105.505 82.680  1.00 104.72 ? 146 MET A CB  1 
ATOM   1095 C  CG  . MET A 1 146 ? 98.563  105.371 83.080  1.00 104.72 ? 146 MET A CG  1 
ATOM   1096 S  SD  . MET A 1 146 ? 98.805  104.831 84.784  1.00 104.72 ? 146 MET A SD  1 
ATOM   1097 C  CE  . MET A 1 146 ? 98.295  103.119 84.683  1.00 104.72 ? 146 MET A CE  1 
ATOM   1098 N  N   . THR A 1 147 ? 96.920  108.459 81.370  1.00 105.91 ? 147 THR A N   1 
ATOM   1099 C  CA  . THR A 1 147 ? 97.632  109.591 80.788  1.00 105.91 ? 147 THR A CA  1 
ATOM   1100 C  C   . THR A 1 147 ? 97.340  110.900 81.510  1.00 105.91 ? 147 THR A C   1 
ATOM   1101 O  O   . THR A 1 147 ? 98.251  111.720 81.671  1.00 105.91 ? 147 THR A O   1 
ATOM   1102 C  CB  . THR A 1 147 ? 97.276  109.735 79.307  1.00 105.91 ? 147 THR A CB  1 
ATOM   1103 O  OG1 . THR A 1 147 ? 95.892  109.419 79.113  1.00 105.91 ? 147 THR A OG1 1 
ATOM   1104 C  CG2 . THR A 1 147 ? 98.130  108.802 78.462  1.00 105.91 ? 147 THR A CG2 1 
ATOM   1105 N  N   . SER A 1 148 ? 96.101  111.117 81.940  1.00 112.72 ? 148 SER A N   1 
ATOM   1106 C  CA  . SER A 1 148 ? 95.723  112.358 82.607  1.00 112.72 ? 148 SER A CA  1 
ATOM   1107 C  C   . SER A 1 148 ? 96.398  112.486 83.968  1.00 112.72 ? 148 SER A C   1 
ATOM   1108 O  O   . SER A 1 148 ? 96.792  111.492 84.577  1.00 112.72 ? 148 SER A O   1 
ATOM   1109 C  CB  . SER A 1 148 ? 94.203  112.438 82.766  1.00 112.72 ? 148 SER A CB  1 
ATOM   1110 N  N   . MET B 2 1   ? 102.018 86.402  64.311  1.00 154.02 ? 1   MET D N   1 
ATOM   1111 C  CA  . MET B 2 1   ? 103.006 87.309  64.882  1.00 154.02 ? 1   MET D CA  1 
ATOM   1112 C  C   . MET B 2 1   ? 103.742 88.075  63.787  1.00 154.02 ? 1   MET D C   1 
ATOM   1113 O  O   . MET B 2 1   ? 104.087 87.511  62.749  1.00 154.02 ? 1   MET D O   1 
ATOM   1114 C  CB  . MET B 2 1   ? 104.005 86.538  65.748  1.00 154.02 ? 1   MET D CB  1 
ATOM   1115 C  CG  . MET B 2 1   ? 104.869 87.418  66.637  1.00 154.02 ? 1   MET D CG  1 
ATOM   1116 S  SD  . MET B 2 1   ? 106.623 87.016  66.535  1.00 154.02 ? 1   MET D SD  1 
ATOM   1117 C  CE  . MET B 2 1   ? 107.071 87.838  65.008  1.00 154.02 ? 1   MET D CE  1 
ATOM   1118 N  N   . ASP B 2 2   ? 103.979 89.363  64.026  1.00 143.14 ? 2   ASP D N   1 
ATOM   1119 C  CA  . ASP B 2 2   ? 104.675 90.205  63.065  1.00 143.14 ? 2   ASP D CA  1 
ATOM   1120 C  C   . ASP B 2 2   ? 105.453 91.277  63.814  1.00 143.14 ? 2   ASP D C   1 
ATOM   1121 O  O   . ASP B 2 2   ? 105.362 91.403  65.038  1.00 143.14 ? 2   ASP D O   1 
ATOM   1122 C  CB  . ASP B 2 2   ? 103.701 90.829  62.057  1.00 143.14 ? 2   ASP D CB  1 
ATOM   1123 C  CG  . ASP B 2 2   ? 102.467 91.416  62.718  1.00 143.14 ? 2   ASP D CG  1 
ATOM   1124 O  OD1 . ASP B 2 2   ? 102.514 91.705  63.932  1.00 143.14 ? 2   ASP D OD1 1 
ATOM   1125 O  OD2 . ASP B 2 2   ? 101.446 91.587  62.020  1.00 143.14 ? 2   ASP D OD2 1 
ATOM   1126 N  N   . GLU B 2 3   ? 106.231 92.053  63.055  1.00 134.08 ? 3   GLU D N   1 
ATOM   1127 C  CA  . GLU B 2 3   ? 107.065 93.087  63.658  1.00 134.08 ? 3   GLU D CA  1 
ATOM   1128 C  C   . GLU B 2 3   ? 106.228 94.238  64.206  1.00 134.08 ? 3   GLU D C   1 
ATOM   1129 O  O   . GLU B 2 3   ? 106.640 94.906  65.163  1.00 134.08 ? 3   GLU D O   1 
ATOM   1130 C  CB  . GLU B 2 3   ? 108.081 93.594  62.633  1.00 134.08 ? 3   GLU D CB  1 
ATOM   1131 C  CG  . GLU B 2 3   ? 109.156 94.504  63.201  1.00 134.08 ? 3   GLU D CG  1 
ATOM   1132 C  CD  . GLU B 2 3   ? 108.821 95.971  63.044  1.00 134.08 ? 3   GLU D CD  1 
ATOM   1133 O  OE1 . GLU B 2 3   ? 107.894 96.292  62.270  1.00 134.08 ? 3   GLU D OE1 1 
ATOM   1134 O  OE2 . GLU B 2 3   ? 109.487 96.806  63.691  1.00 134.08 ? 3   GLU D OE2 1 
ATOM   1135 N  N   . ASN B 2 4   ? 105.056 94.487  63.615  1.00 129.54 ? 4   ASN D N   1 
ATOM   1136 C  CA  . ASN B 2 4   ? 104.180 95.544  64.112  1.00 129.54 ? 4   ASN D CA  1 
ATOM   1137 C  C   . ASN B 2 4   ? 103.707 95.250  65.531  1.00 129.54 ? 4   ASN D C   1 
ATOM   1138 O  O   . ASN B 2 4   ? 103.635 96.157  66.371  1.00 129.54 ? 4   ASN D O   1 
ATOM   1139 C  CB  . ASN B 2 4   ? 102.986 95.718  63.173  1.00 129.54 ? 4   ASN D CB  1 
ATOM   1140 C  CG  . ASN B 2 4   ? 102.048 96.820  63.622  1.00 129.54 ? 4   ASN D CG  1 
ATOM   1141 O  OD1 . ASN B 2 4   ? 102.484 97.907  64.002  1.00 129.54 ? 4   ASN D OD1 1 
ATOM   1142 N  ND2 . ASN B 2 4   ? 100.750 96.544  63.581  1.00 129.54 ? 4   ASN D ND2 1 
ATOM   1143 N  N   . ALA B 2 5   ? 103.372 93.988  65.814  1.00 124.05 ? 5   ALA D N   1 
ATOM   1144 C  CA  . ALA B 2 5   ? 102.986 93.613  67.169  1.00 124.05 ? 5   ALA D CA  1 
ATOM   1145 C  C   . ALA B 2 5   ? 104.134 93.830  68.144  1.00 124.05 ? 5   ALA D C   1 
ATOM   1146 O  O   . ALA B 2 5   ? 103.921 94.285  69.274  1.00 124.05 ? 5   ALA D O   1 
ATOM   1147 C  CB  . ALA B 2 5   ? 102.520 92.157  67.200  1.00 124.05 ? 5   ALA D CB  1 
ATOM   1148 N  N   . ILE B 2 6   ? 105.361 93.515  67.722  1.00 122.79 ? 6   ILE D N   1 
ATOM   1149 C  CA  . ILE B 2 6   ? 106.526 93.739  68.574  1.00 122.79 ? 6   ILE D CA  1 
ATOM   1150 C  C   . ILE B 2 6   ? 106.694 95.226  68.862  1.00 122.79 ? 6   ILE D C   1 
ATOM   1151 O  O   . ILE B 2 6   ? 106.971 95.630  69.999  1.00 122.79 ? 6   ILE D O   1 
ATOM   1152 C  CB  . ILE B 2 6   ? 107.788 93.145  67.921  1.00 122.79 ? 6   ILE D CB  1 
ATOM   1153 C  CG1 . ILE B 2 6   ? 107.638 91.632  67.751  1.00 122.79 ? 6   ILE D CG1 1 
ATOM   1154 C  CG2 . ILE B 2 6   ? 109.023 93.474  68.746  1.00 122.79 ? 6   ILE D CG2 1 
ATOM   1155 C  CD1 . ILE B 2 6   ? 107.608 90.869  69.056  1.00 122.79 ? 6   ILE D CD1 1 
ATOM   1156 N  N   . ARG B 2 7   ? 106.534 96.062  67.833  1.00 120.37 ? 7   ARG D N   1 
ATOM   1157 C  CA  . ARG B 2 7   ? 106.660 97.505  68.021  1.00 120.37 ? 7   ARG D CA  1 
ATOM   1158 C  C   . ARG B 2 7   ? 105.608 98.028  68.991  1.00 120.37 ? 7   ARG D C   1 
ATOM   1159 O  O   . ARG B 2 7   ? 105.912 98.816  69.896  1.00 120.37 ? 7   ARG D O   1 
ATOM   1160 C  CB  . ARG B 2 7   ? 106.552 98.222  66.674  1.00 120.37 ? 7   ARG D CB  1 
ATOM   1161 C  CG  . ARG B 2 7   ? 107.886 98.481  65.995  1.00 120.37 ? 7   ARG D CG  1 
ATOM   1162 C  CD  . ARG B 2 7   ? 107.717 99.339  64.748  1.00 120.37 ? 7   ARG D CD  1 
ATOM   1163 N  NE  . ARG B 2 7   ? 107.204 98.575  63.618  1.00 120.37 ? 7   ARG D NE  1 
ATOM   1164 C  CZ  . ARG B 2 7   ? 106.249 98.994  62.800  1.00 120.37 ? 7   ARG D CZ  1 
ATOM   1165 N  NH1 . ARG B 2 7   ? 105.677 100.177 62.954  1.00 120.37 ? 7   ARG D NH1 1 
ATOM   1166 N  NH2 . ARG B 2 7   ? 105.858 98.208  61.801  1.00 120.37 ? 7   ARG D NH2 1 
ATOM   1167 N  N   . ALA B 2 8   ? 104.357 97.591  68.822  1.00 110.84 ? 8   ALA D N   1 
ATOM   1168 C  CA  . ALA B 2 8   ? 103.298 98.030  69.725  1.00 110.84 ? 8   ALA D CA  1 
ATOM   1169 C  C   . ALA B 2 8   ? 103.570 97.575  71.153  1.00 110.84 ? 8   ALA D C   1 
ATOM   1170 O  O   . ALA B 2 8   ? 103.391 98.346  72.107  1.00 110.84 ? 8   ALA D O   1 
ATOM   1171 C  CB  . ALA B 2 8   ? 101.946 97.508  69.241  1.00 110.84 ? 8   ALA D CB  1 
ATOM   1172 N  N   . ALA B 2 9   ? 104.011 96.325  71.318  1.00 108.99 ? 9   ALA D N   1 
ATOM   1173 C  CA  . ALA B 2 9   ? 104.281 95.799  72.649  1.00 108.99 ? 9   ALA D CA  1 
ATOM   1174 C  C   . ALA B 2 9   ? 105.399 96.575  73.331  1.00 108.99 ? 9   ALA D C   1 
ATOM   1175 O  O   . ALA B 2 9   ? 105.281 96.948  74.503  1.00 108.99 ? 9   ALA D O   1 
ATOM   1176 C  CB  . ALA B 2 9   ? 104.628 94.313  72.564  1.00 108.99 ? 9   ALA D CB  1 
ATOM   1177 N  N   . ILE B 2 10  ? 106.491 96.842  72.609  1.00 107.05 ? 10  ILE D N   1 
ATOM   1178 C  CA  . ILE B 2 10  ? 107.603 97.553  73.234  1.00 107.05 ? 10  ILE D CA  1 
ATOM   1179 C  C   . ILE B 2 10  ? 107.223 98.998  73.535  1.00 107.05 ? 10  ILE D C   1 
ATOM   1180 O  O   . ILE B 2 10  ? 107.641 99.550  74.560  1.00 107.05 ? 10  ILE D O   1 
ATOM   1181 C  CB  . ILE B 2 10  ? 108.881 97.461  72.374  1.00 107.05 ? 10  ILE D CB  1 
ATOM   1182 C  CG1 . ILE B 2 10  ? 108.699 98.151  71.022  1.00 107.05 ? 10  ILE D CG1 1 
ATOM   1183 C  CG2 . ILE B 2 10  ? 109.297 96.008  72.192  1.00 107.05 ? 10  ILE D CG2 1 
ATOM   1184 C  CD1 . ILE B 2 10  ? 109.976 98.269  70.221  1.00 107.05 ? 10  ILE D CD1 1 
ATOM   1185 N  N   . PHE B 2 11  ? 106.421 99.634  72.674  1.00 107.02 ? 11  PHE D N   1 
ATOM   1186 C  CA  . PHE B 2 11  ? 105.974 100.994 72.959  1.00 107.02 ? 11  PHE D CA  1 
ATOM   1187 C  C   . PHE B 2 11  ? 105.125 101.043 74.225  1.00 107.02 ? 11  PHE D C   1 
ATOM   1188 O  O   . PHE B 2 11  ? 105.355 101.881 75.112  1.00 107.02 ? 11  PHE D O   1 
ATOM   1189 C  CB  . PHE B 2 11  ? 105.192 101.542 71.766  1.00 107.02 ? 11  PHE D CB  1 
ATOM   1190 C  CG  . PHE B 2 11  ? 105.285 103.031 71.610  1.00 107.02 ? 11  PHE D CG  1 
ATOM   1191 C  CD1 . PHE B 2 11  ? 104.140 103.803 71.525  1.00 107.02 ? 11  PHE D CD1 1 
ATOM   1192 C  CD2 . PHE B 2 11  ? 106.518 103.658 71.544  1.00 107.02 ? 11  PHE D CD2 1 
ATOM   1193 C  CE1 . PHE B 2 11  ? 104.221 105.174 71.381  1.00 107.02 ? 11  PHE D CE1 1 
ATOM   1194 C  CE2 . PHE B 2 11  ? 106.606 105.029 71.399  1.00 107.02 ? 11  PHE D CE2 1 
ATOM   1195 C  CZ  . PHE B 2 11  ? 105.456 105.788 71.317  1.00 107.02 ? 11  PHE D CZ  1 
ATOM   1196 N  N   . ILE B 2 12  ? 104.145 100.142 74.333  1.00 107.20 ? 12  ILE D N   1 
ATOM   1197 C  CA  . ILE B 2 12  ? 103.293 100.112 75.517  1.00 107.20 ? 12  ILE D CA  1 
ATOM   1198 C  C   . ILE B 2 12  ? 104.117 99.786  76.757  1.00 107.20 ? 12  ILE D C   1 
ATOM   1199 O  O   . ILE B 2 12  ? 103.885 100.339 77.840  1.00 107.20 ? 12  ILE D O   1 
ATOM   1200 C  CB  . ILE B 2 12  ? 102.142 99.109  75.313  1.00 107.20 ? 12  ILE D CB  1 
ATOM   1201 C  CG1 . ILE B 2 12  ? 101.150 99.646  74.280  1.00 107.20 ? 12  ILE D CG1 1 
ATOM   1202 C  CG2 . ILE B 2 12  ? 101.429 98.827  76.625  1.00 107.20 ? 12  ILE D CG2 1 
ATOM   1203 C  CD1 . ILE B 2 12  ? 100.177 98.606  73.772  1.00 107.20 ? 12  ILE D CD1 1 
ATOM   1204 N  N   . GLN B 2 13  ? 105.099 98.894  76.615  1.00 105.40 ? 13  GLN D N   1 
ATOM   1205 C  CA  . GLN B 2 13  ? 105.943 98.513  77.740  1.00 105.40 ? 13  GLN D CA  1 
ATOM   1206 C  C   . GLN B 2 13  ? 106.766 99.700  78.229  1.00 105.40 ? 13  GLN D C   1 
ATOM   1207 O  O   . GLN B 2 13  ? 106.880 99.939  79.439  1.00 105.40 ? 13  GLN D O   1 
ATOM   1208 C  CB  . GLN B 2 13  ? 106.846 97.357  77.314  1.00 105.40 ? 13  GLN D CB  1 
ATOM   1209 C  CG  . GLN B 2 13  ? 106.207 95.989  77.480  1.00 105.40 ? 13  GLN D CG  1 
ATOM   1210 C  CD  . GLN B 2 13  ? 107.070 94.874  76.927  1.00 105.40 ? 13  GLN D CD  1 
ATOM   1211 O  OE1 . GLN B 2 13  ? 107.813 95.069  75.965  1.00 105.40 ? 13  GLN D OE1 1 
ATOM   1212 N  NE2 . GLN B 2 13  ? 106.963 93.690  77.519  1.00 105.40 ? 13  GLN D NE2 1 
ATOM   1213 N  N   . LYS B 2 14  ? 107.341 100.460 77.294  1.00 94.21  ? 14  LYS D N   1 
ATOM   1214 C  CA  . LYS B 2 14  ? 108.087 101.662 77.647  1.00 94.21  ? 14  LYS D CA  1 
ATOM   1215 C  C   . LYS B 2 14  ? 107.196 102.651 78.387  1.00 94.21  ? 14  LYS D C   1 
ATOM   1216 O  O   . LYS B 2 14  ? 107.588 103.219 79.414  1.00 94.21  ? 14  LYS D O   1 
ATOM   1217 C  CB  . LYS B 2 14  ? 108.657 102.310 76.384  1.00 94.21  ? 14  LYS D CB  1 
ATOM   1218 C  CG  . LYS B 2 14  ? 109.883 101.634 75.799  1.00 94.21  ? 14  LYS D CG  1 
ATOM   1219 C  CD  . LYS B 2 14  ? 110.123 102.131 74.380  1.00 94.21  ? 14  LYS D CD  1 
ATOM   1220 C  CE  . LYS B 2 14  ? 111.522 101.807 73.892  1.00 94.21  ? 14  LYS D CE  1 
ATOM   1221 N  NZ  . LYS B 2 14  ? 112.461 102.939 74.115  1.00 94.21  ? 14  LYS D NZ  1 
ATOM   1222 N  N   . TRP B 2 15  ? 105.987 102.871 77.866  1.00 93.86  ? 15  TRP D N   1 
ATOM   1223 C  CA  . TRP B 2 15  ? 105.073 103.825 78.490  1.00 93.86  ? 15  TRP D CA  1 
ATOM   1224 C  C   . TRP B 2 15  ? 104.710 103.395 79.909  1.00 93.86  ? 15  TRP D C   1 
ATOM   1225 O  O   . TRP B 2 15  ? 104.724 104.208 80.848  1.00 93.86  ? 15  TRP D O   1 
ATOM   1226 C  CB  . TRP B 2 15  ? 103.828 103.973 77.614  1.00 93.86  ? 15  TRP D CB  1 
ATOM   1227 C  CG  . TRP B 2 15  ? 102.732 104.797 78.200  1.00 93.86  ? 15  TRP D CG  1 
ATOM   1228 C  CD1 . TRP B 2 15  ? 102.695 106.155 78.311  1.00 93.86  ? 15  TRP D CD1 1 
ATOM   1229 C  CD2 . TRP B 2 15  ? 101.486 104.318 78.717  1.00 93.86  ? 15  TRP D CD2 1 
ATOM   1230 N  NE1 . TRP B 2 15  ? 101.512 106.551 78.886  1.00 93.86  ? 15  TRP D NE1 1 
ATOM   1231 C  CE2 . TRP B 2 15  ? 100.751 105.441 79.143  1.00 93.86  ? 15  TRP D CE2 1 
ATOM   1232 C  CE3 . TRP B 2 15  ? 100.924 103.047 78.870  1.00 93.86  ? 15  TRP D CE3 1 
ATOM   1233 C  CZ2 . TRP B 2 15  ? 99.485  105.332 79.711  1.00 93.86  ? 15  TRP D CZ2 1 
ATOM   1234 C  CZ3 . TRP B 2 15  ? 99.667  102.941 79.434  1.00 93.86  ? 15  TRP D CZ3 1 
ATOM   1235 C  CH2 . TRP B 2 15  ? 98.962  104.076 79.847  1.00 93.86  ? 15  TRP D CH2 1 
ATOM   1236 N  N   . TYR B 2 16  ? 104.402 102.108 80.090  1.00 86.30  ? 16  TYR D N   1 
ATOM   1237 C  CA  . TYR B 2 16  ? 104.028 101.617 81.411  1.00 86.30  ? 16  TYR D CA  1 
ATOM   1238 C  C   . TYR B 2 16  ? 105.191 101.718 82.390  1.00 86.30  ? 16  TYR D C   1 
ATOM   1239 O  O   . TYR B 2 16  ? 105.000 102.094 83.554  1.00 86.30  ? 16  TYR D O   1 
ATOM   1240 C  CB  . TYR B 2 16  ? 103.529 100.177 81.319  1.00 86.30  ? 16  TYR D CB  1 
ATOM   1241 C  CG  . TYR B 2 16  ? 103.126 99.594  82.653  1.00 86.30  ? 16  TYR D CG  1 
ATOM   1242 C  CD1 . TYR B 2 16  ? 101.956 99.998  83.281  1.00 86.30  ? 16  TYR D CD1 1 
ATOM   1243 C  CD2 . TYR B 2 16  ? 103.915 98.645  83.286  1.00 86.30  ? 16  TYR D CD2 1 
ATOM   1244 C  CE1 . TYR B 2 16  ? 101.583 99.472  84.500  1.00 86.30  ? 16  TYR D CE1 1 
ATOM   1245 C  CE2 . TYR B 2 16  ? 103.550 98.113  84.506  1.00 86.30  ? 16  TYR D CE2 1 
ATOM   1246 C  CZ  . TYR B 2 16  ? 102.383 98.530  85.109  1.00 86.30  ? 16  TYR D CZ  1 
ATOM   1247 O  OH  . TYR B 2 16  ? 102.013 98.003  86.324  1.00 86.30  ? 16  TYR D OH  1 
ATOM   1248 N  N   . ARG B 2 17  ? 106.405 101.383 81.943  1.00 86.90  ? 17  ARG D N   1 
ATOM   1249 C  CA  . ARG B 2 17  ? 107.560 101.500 82.827  1.00 86.90  ? 17  ARG D CA  1 
ATOM   1250 C  C   . ARG B 2 17  ? 107.830 102.949 83.207  1.00 86.90  ? 17  ARG D C   1 
ATOM   1251 O  O   . ARG B 2 17  ? 108.190 103.234 84.357  1.00 86.90  ? 17  ARG D O   1 
ATOM   1252 C  CB  . ARG B 2 17  ? 108.792 100.876 82.172  1.00 86.90  ? 17  ARG D CB  1 
ATOM   1253 C  CG  . ARG B 2 17  ? 108.858 99.363  82.310  1.00 86.90  ? 17  ARG D CG  1 
ATOM   1254 C  CD  . ARG B 2 17  ? 110.095 98.797  81.635  1.00 86.90  ? 17  ARG D CD  1 
ATOM   1255 N  NE  . ARG B 2 17  ? 110.336 97.411  82.020  1.00 86.90  ? 17  ARG D NE  1 
ATOM   1256 C  CZ  . ARG B 2 17  ? 110.875 96.496  81.226  1.00 86.90  ? 17  ARG D CZ  1 
ATOM   1257 N  NH1 . ARG B 2 17  ? 111.240 96.784  79.988  1.00 86.90  ? 17  ARG D NH1 1 
ATOM   1258 N  NH2 . ARG B 2 17  ? 111.050 95.261  81.686  1.00 86.90  ? 17  ARG D NH2 1 
ATOM   1259 N  N   . ARG B 2 18  ? 107.658 103.878 82.263  1.00 78.37  ? 18  ARG D N   1 
ATOM   1260 C  CA  . ARG B 2 18  ? 107.824 105.292 82.580  1.00 78.37  ? 18  ARG D CA  1 
ATOM   1261 C  C   . ARG B 2 18  ? 106.829 105.733 83.646  1.00 78.37  ? 18  ARG D C   1 
ATOM   1262 O  O   . ARG B 2 18  ? 107.189 106.433 84.603  1.00 78.37  ? 18  ARG D O   1 
ATOM   1263 C  CB  . ARG B 2 18  ? 107.662 106.131 81.312  1.00 78.37  ? 18  ARG D CB  1 
ATOM   1264 C  CG  . ARG B 2 18  ? 108.063 107.586 81.468  1.00 78.37  ? 18  ARG D CG  1 
ATOM   1265 C  CD  . ARG B 2 18  ? 107.772 108.370 80.200  1.00 78.37  ? 18  ARG D CD  1 
ATOM   1266 N  NE  . ARG B 2 18  ? 106.341 108.563 79.998  1.00 78.37  ? 18  ARG D NE  1 
ATOM   1267 C  CZ  . ARG B 2 18  ? 105.815 109.333 79.057  1.00 78.37  ? 18  ARG D CZ  1 
ATOM   1268 N  NH1 . ARG B 2 18  ? 106.575 110.000 78.204  1.00 78.37  ? 18  ARG D NH1 1 
ATOM   1269 N  NH2 . ARG B 2 18  ? 104.492 109.437 78.968  1.00 78.37  ? 18  ARG D NH2 1 
ATOM   1270 N  N   . HIS B 2 19  ? 105.566 105.322 83.504  1.00 79.44  ? 19  HIS D N   1 
ATOM   1271 C  CA  . HIS B 2 19  ? 104.572 105.708 84.502  1.00 79.44  ? 19  HIS D CA  1 
ATOM   1272 C  C   . HIS B 2 19  ? 104.858 105.075 85.860  1.00 79.44  ? 19  HIS D C   1 
ATOM   1273 O  O   . HIS B 2 19  ? 104.654 105.716 86.901  1.00 79.44  ? 19  HIS D O   1 
ATOM   1274 C  CB  . HIS B 2 19  ? 103.171 105.347 84.019  1.00 79.44  ? 19  HIS D CB  1 
ATOM   1275 C  CG  . HIS B 2 19  ? 102.560 106.385 83.131  1.00 79.44  ? 19  HIS D CG  1 
ATOM   1276 N  ND1 . HIS B 2 19  ? 101.312 106.921 83.361  1.00 79.44  ? 19  HIS D ND1 1 
ATOM   1277 C  CD2 . HIS B 2 19  ? 103.028 106.986 82.012  1.00 79.44  ? 19  HIS D CD2 1 
ATOM   1278 C  CE1 . HIS B 2 19  ? 101.036 107.808 82.421  1.00 79.44  ? 19  HIS D CE1 1 
ATOM   1279 N  NE2 . HIS B 2 19  ? 102.061 107.867 81.591  1.00 79.44  ? 19  HIS D NE2 1 
ATOM   1280 N  N   . GLN B 2 20  ? 105.336 103.828 85.873  1.00 72.05  ? 20  GLN D N   1 
ATOM   1281 C  CA  . GLN B 2 20  ? 105.705 103.190 87.132  1.00 72.05  ? 20  GLN D CA  1 
ATOM   1282 C  C   . GLN B 2 20  ? 106.842 103.943 87.815  1.00 72.05  ? 20  GLN D C   1 
ATOM   1283 O  O   . GLN B 2 20  ? 106.827 104.141 89.037  1.00 72.05  ? 20  GLN D O   1 
ATOM   1284 C  CB  . GLN B 2 20  ? 106.092 101.732 86.887  1.00 72.05  ? 20  GLN D CB  1 
ATOM   1285 C  CG  . GLN B 2 20  ? 104.910 100.783 86.798  1.00 72.05  ? 20  GLN D CG  1 
ATOM   1286 C  CD  . GLN B 2 20  ? 104.223 100.579 88.133  1.00 72.05  ? 20  GLN D CD  1 
ATOM   1287 O  OE1 . GLN B 2 20  ? 104.828 100.760 89.189  1.00 72.05  ? 20  GLN D OE1 1 
ATOM   1288 N  NE2 . GLN B 2 20  ? 102.952 100.200 88.092  1.00 72.05  ? 20  GLN D NE2 1 
ATOM   1289 N  N   . ALA B 2 21  ? 107.841 104.370 87.038  1.00 64.20  ? 21  ALA D N   1 
ATOM   1290 C  CA  . ALA B 2 21  ? 108.938 105.145 87.612  1.00 64.20  ? 21  ALA D CA  1 
ATOM   1291 C  C   . ALA B 2 21  ? 108.441 106.474 88.170  1.00 64.20  ? 21  ALA D C   1 
ATOM   1292 O  O   . ALA B 2 21  ? 108.896 106.922 89.232  1.00 64.20  ? 21  ALA D O   1 
ATOM   1293 C  CB  . ALA B 2 21  ? 110.025 105.374 86.564  1.00 64.20  ? 21  ALA D CB  1 
ATOM   1294 N  N   . ARG B 2 22  ? 107.513 107.123 87.463  1.00 60.24  ? 22  ARG D N   1 
ATOM   1295 C  CA  . ARG B 2 22  ? 106.943 108.369 87.969  1.00 60.24  ? 22  ARG D CA  1 
ATOM   1296 C  C   . ARG B 2 22  ? 106.239 108.150 89.304  1.00 60.24  ? 22  ARG D C   1 
ATOM   1297 O  O   . ARG B 2 22  ? 106.404 108.940 90.246  1.00 60.24  ? 22  ARG D O   1 
ATOM   1298 C  CB  . ARG B 2 22  ? 105.974 108.954 86.943  1.00 60.24  ? 22  ARG D CB  1 
ATOM   1299 C  CG  . ARG B 2 22  ? 105.336 110.265 87.360  1.00 60.24  ? 22  ARG D CG  1 
ATOM   1300 C  CD  . ARG B 2 22  ? 104.421 110.790 86.268  1.00 60.24  ? 22  ARG D CD  1 
ATOM   1301 N  NE  . ARG B 2 22  ? 105.158 111.107 85.050  1.00 60.24  ? 22  ARG D NE  1 
ATOM   1302 C  CZ  . ARG B 2 22  ? 104.600 111.293 83.863  1.00 60.24  ? 22  ARG D CZ  1 
ATOM   1303 N  NH1 . ARG B 2 22  ? 103.291 111.202 83.692  1.00 60.24  ? 22  ARG D NH1 1 
ATOM   1304 N  NH2 . ARG B 2 22  ? 105.373 111.576 82.819  1.00 60.24  ? 22  ARG D NH2 1 
ATOM   1305 N  N   . ARG B 2 23  ? 105.454 107.075 89.406  1.00 62.84  ? 23  ARG D N   1 
ATOM   1306 C  CA  . ARG B 2 23  ? 104.780 106.777 90.667  1.00 62.84  ? 23  ARG D CA  1 
ATOM   1307 C  C   . ARG B 2 23  ? 105.784 106.491 91.779  1.00 62.84  ? 23  ARG D C   1 
ATOM   1308 O  O   . ARG B 2 23  ? 105.577 106.895 92.930  1.00 62.84  ? 23  ARG D O   1 
ATOM   1309 C  CB  . ARG B 2 23  ? 103.822 105.602 90.490  1.00 62.84  ? 23  ARG D CB  1 
ATOM   1310 C  CG  . ARG B 2 23  ? 102.581 105.696 91.358  1.00 62.84  ? 23  ARG D CG  1 
ATOM   1311 C  CD  . ARG B 2 23  ? 101.439 106.392 90.637  1.00 62.84  ? 23  ARG D CD  1 
ATOM   1312 N  NE  . ARG B 2 23  ? 101.011 105.660 89.451  1.00 62.84  ? 23  ARG D NE  1 
ATOM   1313 C  CZ  . ARG B 2 23  ? 100.162 106.130 88.547  1.00 62.84  ? 23  ARG D CZ  1 
ATOM   1314 N  NH1 . ARG B 2 23  ? 99.626  107.334 88.662  1.00 62.84  ? 23  ARG D NH1 1 
ATOM   1315 N  NH2 . ARG B 2 23  ? 99.841  105.371 87.502  1.00 62.84  ? 23  ARG D NH2 1 
ATOM   1316 N  N   . GLU B 2 24  ? 106.872 105.788 91.457  1.00 54.25  ? 24  GLU D N   1 
ATOM   1317 C  CA  . GLU B 2 24  ? 107.898 105.515 92.460  1.00 54.25  ? 24  GLU D CA  1 
ATOM   1318 C  C   . GLU B 2 24  ? 108.528 106.807 92.969  1.00 54.25  ? 24  GLU D C   1 
ATOM   1319 O  O   . GLU B 2 24  ? 108.758 106.967 94.177  1.00 54.25  ? 24  GLU D O   1 
ATOM   1320 C  CB  . GLU B 2 24  ? 108.966 104.592 91.876  1.00 54.25  ? 24  GLU D CB  1 
ATOM   1321 C  CG  . GLU B 2 24  ? 110.058 104.199 92.854  1.00 54.25  ? 24  GLU D CG  1 
ATOM   1322 C  CD  . GLU B 2 24  ? 109.553 103.300 93.965  1.00 54.25  ? 24  GLU D CD  1 
ATOM   1323 O  OE1 . GLU B 2 24  ? 108.529 102.615 93.760  1.00 54.25  ? 24  GLU D OE1 1 
ATOM   1324 O  OE2 . GLU B 2 24  ? 110.181 103.274 95.044  1.00 54.25  ? 24  GLU D OE2 1 
ATOM   1325 N  N   . MET B 2 25  ? 108.814 107.741 92.061  1.00 52.51  ? 25  MET D N   1 
ATOM   1326 C  CA  . MET B 2 25  ? 109.373 109.026 92.472  1.00 52.51  ? 25  MET D CA  1 
ATOM   1327 C  C   . MET B 2 25  ? 108.397 109.784 93.366  1.00 52.51  ? 25  MET D C   1 
ATOM   1328 O  O   . MET B 2 25  ? 108.798 110.407 94.358  1.00 52.51  ? 25  MET D O   1 
ATOM   1329 C  CB  . MET B 2 25  ? 109.741 109.856 91.243  1.00 52.51  ? 25  MET D CB  1 
ATOM   1330 C  CG  . MET B 2 25  ? 110.862 110.850 91.482  1.00 52.51  ? 25  MET D CG  1 
ATOM   1331 S  SD  . MET B 2 25  ? 110.783 112.248 90.349  1.00 52.51  ? 25  MET D SD  1 
ATOM   1332 C  CE  . MET B 2 25  ? 109.215 112.972 90.822  1.00 52.51  ? 25  MET D CE  1 
ATOM   1333 N  N   . GLN B 2 26  ? 107.106 109.742 93.024  1.00 50.07  ? 26  GLN D N   1 
ATOM   1334 C  CA  . GLN B 2 26  ? 106.104 110.388 93.870  1.00 50.07  ? 26  GLN D CA  1 
ATOM   1335 C  C   . GLN B 2 26  ? 106.080 109.776 95.267  1.00 50.07  ? 26  GLN D C   1 
ATOM   1336 O  O   . GLN B 2 26  ? 105.992 110.497 96.272  1.00 50.07  ? 26  GLN D O   1 
ATOM   1337 C  CB  . GLN B 2 26  ? 104.726 110.290 93.219  1.00 50.07  ? 26  GLN D CB  1 
ATOM   1338 C  CG  . GLN B 2 26  ? 103.665 111.149 93.883  1.00 50.07  ? 26  GLN D CG  1 
ATOM   1339 C  CD  . GLN B 2 26  ? 103.620 112.556 93.326  1.00 50.07  ? 26  GLN D CD  1 
ATOM   1340 O  OE1 . GLN B 2 26  ? 104.643 113.235 93.239  1.00 50.07  ? 26  GLN D OE1 1 
ATOM   1341 N  NE2 . GLN B 2 26  ? 102.430 113.003 92.944  1.00 50.07  ? 26  GLN D NE2 1 
ATOM   1342 N  N   . ARG B 2 27  ? 106.156 108.446 95.347  1.00 54.54  ? 27  ARG D N   1 
ATOM   1343 C  CA  . ARG B 2 27  ? 106.186 107.774 96.643  1.00 54.54  ? 27  ARG D CA  1 
ATOM   1344 C  C   . ARG B 2 27  ? 107.386 108.227 97.464  1.00 54.54  ? 27  ARG D C   1 
ATOM   1345 O  O   . ARG B 2 27  ? 107.269 108.504 98.665  1.00 54.54  ? 27  ARG D O   1 
ATOM   1346 C  CB  . ARG B 2 27  ? 106.224 106.258 96.452  1.00 54.54  ? 27  ARG D CB  1 
ATOM   1347 C  CG  . ARG B 2 27  ? 104.909 105.623 96.050  1.00 54.54  ? 27  ARG D CG  1 
ATOM   1348 C  CD  . ARG B 2 27  ? 104.904 104.122 96.331  1.00 54.54  ? 27  ARG D CD  1 
ATOM   1349 N  NE  . ARG B 2 27  ? 106.202 103.495 96.103  1.00 54.54  ? 27  ARG D NE  1 
ATOM   1350 C  CZ  . ARG B 2 27  ? 107.043 103.132 97.064  1.00 54.54  ? 27  ARG D CZ  1 
ATOM   1351 N  NH1 . ARG B 2 27  ? 106.758 103.328 98.341  1.00 54.54  ? 27  ARG D NH1 1 
ATOM   1352 N  NH2 . ARG B 2 27  ? 108.199 102.563 96.735  1.00 54.54  ? 27  ARG D NH2 1 
ATOM   1353 N  N   . ARG B 2 28  ? 108.558 108.294 96.828  1.00 46.97  ? 28  ARG D N   1 
ATOM   1354 C  CA  . ARG B 2 28  ? 109.760 108.703 97.549  1.00 46.97  ? 28  ARG D CA  1 
ATOM   1355 C  C   . ARG B 2 28  ? 109.643 110.137 98.052  1.00 46.97  ? 28  ARG D C   1 
ATOM   1356 O  O   . ARG B 2 28  ? 110.045 110.443 99.183  1.00 46.97  ? 28  ARG D O   1 
ATOM   1357 C  CB  . ARG B 2 28  ? 110.990 108.539 96.658  1.00 46.97  ? 28  ARG D CB  1 
ATOM   1358 C  CG  . ARG B 2 28  ? 111.299 107.093 96.311  1.00 46.97  ? 28  ARG D CG  1 
ATOM   1359 C  CD  . ARG B 2 28  ? 112.501 106.987 95.392  1.00 46.97  ? 28  ARG D CD  1 
ATOM   1360 N  NE  . ARG B 2 28  ? 113.659 106.418 96.072  1.00 46.97  ? 28  ARG D NE  1 
ATOM   1361 C  CZ  . ARG B 2 28  ? 114.066 105.164 95.932  1.00 46.97  ? 28  ARG D CZ  1 
ATOM   1362 N  NH1 . ARG B 2 28  ? 113.429 104.314 95.145  1.00 46.97  ? 28  ARG D NH1 1 
ATOM   1363 N  NH2 . ARG B 2 28  ? 115.140 104.753 96.600  1.00 46.97  ? 28  ARG D NH2 1 
ATOM   1364 N  N   . CYS B 2 29  ? 109.087 111.030 97.230  1.00 40.54  ? 29  CYS D N   1 
ATOM   1365 C  CA  . CYS B 2 29  ? 108.910 112.415 97.658  1.00 40.54  ? 29  CYS D CA  1 
ATOM   1366 C  C   . CYS B 2 29  ? 107.967 112.508 98.854  1.00 40.54  ? 29  CYS D C   1 
ATOM   1367 O  O   . CYS B 2 29  ? 108.230 113.247 99.813  1.00 40.54  ? 29  CYS D O   1 
ATOM   1368 C  CB  . CYS B 2 29  ? 108.392 113.260 96.495  1.00 40.54  ? 29  CYS D CB  1 
ATOM   1369 S  SG  . CYS B 2 29  ? 108.310 115.029 96.840  1.00 40.54  ? 29  CYS D SG  1 
ATOM   1370 N  N   . ASN B 2 30  ? 106.860 111.760 98.818  1.00 37.08  ? 30  ASN D N   1 
ATOM   1371 C  CA  . ASN B 2 30  ? 105.921 111.790 99.938  1.00 37.08  ? 30  ASN D CA  1 
ATOM   1372 C  C   . ASN B 2 30  ? 106.559 111.245 101.212 1.00 37.08  ? 30  ASN D C   1 
ATOM   1373 O  O   . ASN B 2 30  ? 106.345 111.786 102.307 1.00 37.08  ? 30  ASN D O   1 
ATOM   1374 C  CB  . ASN B 2 30  ? 104.660 111.004 99.588  1.00 37.08  ? 30  ASN D CB  1 
ATOM   1375 C  CG  . ASN B 2 30  ? 103.667 111.826 98.794  1.00 37.08  ? 30  ASN D CG  1 
ATOM   1376 O  OD1 . ASN B 2 30  ? 103.140 112.823 99.282  1.00 37.08  ? 30  ASN D OD1 1 
ATOM   1377 N  ND2 . ASN B 2 30  ? 103.407 111.410 97.561  1.00 37.08  ? 30  ASN D ND2 1 
ATOM   1378 N  N   . TRP B 2 31  ? 107.342 110.171 101.090 1.00 26.87  ? 31  TRP D N   1 
ATOM   1379 C  CA  . TRP B 2 31  ? 108.037 109.631 102.254 1.00 26.87  ? 31  TRP D CA  1 
ATOM   1380 C  C   . TRP B 2 31  ? 109.007 110.650 102.838 1.00 26.87  ? 31  TRP D C   1 
ATOM   1381 O  O   . TRP B 2 31  ? 109.099 110.804 104.064 1.00 26.87  ? 31  TRP D O   1 
ATOM   1382 C  CB  . TRP B 2 31  ? 108.775 108.351 101.874 1.00 26.87  ? 31  TRP D CB  1 
ATOM   1383 C  CG  . TRP B 2 31  ? 109.395 107.658 103.036 1.00 26.87  ? 31  TRP D CG  1 
ATOM   1384 C  CD1 . TRP B 2 31  ? 110.716 107.633 103.364 1.00 26.87  ? 31  TRP D CD1 1 
ATOM   1385 C  CD2 . TRP B 2 31  ? 108.719 106.881 104.028 1.00 26.87  ? 31  TRP D CD2 1 
ATOM   1386 N  NE1 . TRP B 2 31  ? 110.906 106.890 104.502 1.00 26.87  ? 31  TRP D NE1 1 
ATOM   1387 C  CE2 . TRP B 2 31  ? 109.694 106.416 104.929 1.00 26.87  ? 31  TRP D CE2 1 
ATOM   1388 C  CE3 . TRP B 2 31  ? 107.383 106.534 104.241 1.00 26.87  ? 31  TRP D CE3 1 
ATOM   1389 C  CZ2 . TRP B 2 31  ? 109.377 105.623 106.026 1.00 26.87  ? 31  TRP D CZ2 1 
ATOM   1390 C  CZ3 . TRP B 2 31  ? 107.070 105.747 105.330 1.00 26.87  ? 31  TRP D CZ3 1 
ATOM   1391 C  CH2 . TRP B 2 31  ? 108.062 105.300 106.209 1.00 26.87  ? 31  TRP D CH2 1 
ATOM   1392 N  N   . GLN B 2 32  ? 109.744 111.351 101.973 1.00 31.63  ? 32  GLN D N   1 
ATOM   1393 C  CA  . GLN B 2 32  ? 110.661 112.382 102.448 1.00 31.63  ? 32  GLN D CA  1 
ATOM   1394 C  C   . GLN B 2 32  ? 109.910 113.476 103.194 1.00 31.63  ? 32  GLN D C   1 
ATOM   1395 O  O   . GLN B 2 32  ? 110.352 113.938 104.254 1.00 31.63  ? 32  GLN D O   1 
ATOM   1396 C  CB  . GLN B 2 32  ? 111.441 112.972 101.274 1.00 31.63  ? 32  GLN D CB  1 
ATOM   1397 C  CG  . GLN B 2 32  ? 112.643 113.801 101.683 1.00 31.63  ? 32  GLN D CG  1 
ATOM   1398 C  CD  . GLN B 2 32  ? 113.902 112.975 101.821 1.00 31.63  ? 32  GLN D CD  1 
ATOM   1399 O  OE1 . GLN B 2 32  ? 113.844 111.759 102.002 1.00 31.63  ? 32  GLN D OE1 1 
ATOM   1400 N  NE2 . GLN B 2 32  ? 115.052 113.631 101.734 1.00 31.63  ? 32  GLN D NE2 1 
ATOM   1401 N  N   . ILE B 2 33  ? 108.765 113.899 102.654 1.00 27.74  ? 33  ILE D N   1 
ATOM   1402 C  CA  . ILE B 2 33  ? 107.978 114.939 103.312 1.00 27.74  ? 33  ILE D CA  1 
ATOM   1403 C  C   . ILE B 2 33  ? 107.538 114.481 104.697 1.00 27.74  ? 33  ILE D C   1 
ATOM   1404 O  O   . ILE B 2 33  ? 107.663 115.223 105.681 1.00 27.74  ? 33  ILE D O   1 
ATOM   1405 C  CB  . ILE B 2 33  ? 106.774 115.338 102.440 1.00 27.74  ? 33  ILE D CB  1 
ATOM   1406 C  CG1 . ILE B 2 33  ? 107.219 116.261 101.307 1.00 27.74  ? 33  ILE D CG1 1 
ATOM   1407 C  CG2 . ILE B 2 33  ? 105.702 116.009 103.280 1.00 27.74  ? 33  ILE D CG2 1 
ATOM   1408 C  CD1 . ILE B 2 33  ? 106.157 116.486 100.258 1.00 27.74  ? 33  ILE D CD1 1 
ATOM   1409 N  N   . PHE B 2 34  ? 107.027 113.251 104.800 1.00 28.91  ? 34  PHE D N   1 
ATOM   1410 C  CA  . PHE B 2 34  ? 106.571 112.749 106.095 1.00 28.91  ? 34  PHE D CA  1 
ATOM   1411 C  C   . PHE B 2 34  ? 107.711 112.699 107.106 1.00 28.91  ? 34  PHE D C   1 
ATOM   1412 O  O   . PHE B 2 34  ? 107.564 113.150 108.253 1.00 28.91  ? 34  PHE D O   1 
ATOM   1413 C  CB  . PHE B 2 34  ? 105.949 111.362 105.936 1.00 28.91  ? 34  PHE D CB  1 
ATOM   1414 C  CG  . PHE B 2 34  ? 104.531 111.380 105.448 1.00 28.91  ? 34  PHE D CG  1 
ATOM   1415 C  CD1 . PHE B 2 34  ? 103.598 112.222 106.023 1.00 28.91  ? 34  PHE D CD1 1 
ATOM   1416 C  CD2 . PHE B 2 34  ? 104.129 110.539 104.426 1.00 28.91  ? 34  PHE D CD2 1 
ATOM   1417 C  CE1 . PHE B 2 34  ? 102.293 112.234 105.579 1.00 28.91  ? 34  PHE D CE1 1 
ATOM   1418 C  CE2 . PHE B 2 34  ? 102.826 110.546 103.980 1.00 28.91  ? 34  PHE D CE2 1 
ATOM   1419 C  CZ  . PHE B 2 34  ? 101.907 111.394 104.557 1.00 28.91  ? 34  PHE D CZ  1 
ATOM   1420 N  N   . GLN B 2 35  ? 108.856 112.143 106.701 1.00 25.53  ? 35  GLN D N   1 
ATOM   1421 C  CA  . GLN B 2 35  ? 109.969 111.996 107.633 1.00 25.53  ? 35  GLN D CA  1 
ATOM   1422 C  C   . GLN B 2 35  ? 110.481 113.353 108.098 1.00 25.53  ? 35  GLN D C   1 
ATOM   1423 O  O   . GLN B 2 35  ? 110.744 113.557 109.291 1.00 25.53  ? 35  GLN D O   1 
ATOM   1424 C  CB  . GLN B 2 35  ? 111.091 111.185 106.988 1.00 25.53  ? 35  GLN D CB  1 
ATOM   1425 C  CG  . GLN B 2 35  ? 111.051 109.708 107.326 1.00 25.53  ? 35  GLN D CG  1 
ATOM   1426 C  CD  . GLN B 2 35  ? 112.346 109.002 106.989 1.00 25.53  ? 35  GLN D CD  1 
ATOM   1427 O  OE1 . GLN B 2 35  ? 113.165 109.516 106.229 1.00 25.53  ? 35  GLN D OE1 1 
ATOM   1428 N  NE2 . GLN B 2 35  ? 112.540 107.818 107.556 1.00 25.53  ? 35  GLN D NE2 1 
ATOM   1429 N  N   . ASN B 2 36  ? 110.624 114.302 107.167 1.00 31.13  ? 36  ASN D N   1 
ATOM   1430 C  CA  . ASN B 2 36  ? 111.095 115.627 107.551 1.00 31.13  ? 36  ASN D CA  1 
ATOM   1431 C  C   . ASN B 2 36  ? 110.105 116.331 108.469 1.00 31.13  ? 36  ASN D C   1 
ATOM   1432 O  O   . ASN B 2 36  ? 110.520 117.006 109.418 1.00 31.13  ? 36  ASN D O   1 
ATOM   1433 C  CB  . ASN B 2 36  ? 111.370 116.472 106.310 1.00 31.13  ? 36  ASN D CB  1 
ATOM   1434 C  CG  . ASN B 2 36  ? 112.762 116.251 105.756 1.00 31.13  ? 36  ASN D CG  1 
ATOM   1435 O  OD1 . ASN B 2 36  ? 113.376 115.210 105.987 1.00 31.13  ? 36  ASN D OD1 1 
ATOM   1436 N  ND2 . ASN B 2 36  ? 113.270 117.233 105.022 1.00 31.13  ? 36  ASN D ND2 1 
ATOM   1437 N  N   . LEU B 2 37  ? 108.801 116.184 108.214 1.00 28.36  ? 37  LEU D N   1 
ATOM   1438 C  CA  . LEU B 2 37  ? 107.815 116.801 109.094 1.00 28.36  ? 37  LEU D CA  1 
ATOM   1439 C  C   . LEU B 2 37  ? 107.871 116.227 110.503 1.00 28.36  ? 37  LEU D C   1 
ATOM   1440 O  O   . LEU B 2 37  ? 107.751 116.979 111.477 1.00 28.36  ? 37  LEU D O   1 
ATOM   1441 C  CB  . LEU B 2 37  ? 106.413 116.640 108.514 1.00 28.36  ? 37  LEU D CB  1 
ATOM   1442 C  CG  . LEU B 2 37  ? 106.056 117.632 107.409 1.00 28.36  ? 37  LEU D CG  1 
ATOM   1443 C  CD1 . LEU B 2 37  ? 104.608 117.462 106.994 1.00 28.36  ? 37  LEU D CD1 1 
ATOM   1444 C  CD2 . LEU B 2 37  ? 106.322 119.052 107.870 1.00 28.36  ? 37  LEU D CD2 1 
ATOM   1445 N  N   . GLU B 2 38  ? 108.038 114.909 110.641 1.00 31.65  ? 38  GLU D N   1 
ATOM   1446 C  CA  . GLU B 2 38  ? 108.143 114.335 111.982 1.00 31.65  ? 38  GLU D CA  1 
ATOM   1447 C  C   . GLU B 2 38  ? 109.416 114.797 112.686 1.00 31.65  ? 38  GLU D C   1 
ATOM   1448 O  O   . GLU B 2 38  ? 109.396 115.142 113.880 1.00 31.65  ? 38  GLU D O   1 
ATOM   1449 C  CB  . GLU B 2 38  ? 108.093 112.809 111.913 1.00 31.65  ? 38  GLU D CB  1 
ATOM   1450 C  CG  . GLU B 2 38  ? 108.234 112.135 113.268 1.00 31.65  ? 38  GLU D CG  1 
ATOM   1451 C  CD  . GLU B 2 38  ? 108.268 110.623 113.174 1.00 31.65  ? 38  GLU D CD  1 
ATOM   1452 O  OE1 . GLU B 2 38  ? 109.226 110.083 112.583 1.00 31.65  ? 38  GLU D OE1 1 
ATOM   1453 O  OE2 . GLU B 2 38  ? 107.339 109.973 113.697 1.00 31.65  ? 38  GLU D OE2 1 
ATOM   1454 N  N   . TYR B 2 39  ? 110.538 114.807 111.960 1.00 27.84  ? 39  TYR D N   1 
ATOM   1455 C  CA  . TYR B 2 39  ? 111.806 115.193 112.571 1.00 27.84  ? 39  TYR D CA  1 
ATOM   1456 C  C   . TYR B 2 39  ? 111.798 116.654 112.998 1.00 27.84  ? 39  TYR D C   1 
ATOM   1457 O  O   . TYR B 2 39  ? 112.377 117.006 114.030 1.00 27.84  ? 39  TYR D O   1 
ATOM   1458 C  CB  . TYR B 2 39  ? 112.962 114.921 111.609 1.00 27.84  ? 39  TYR D CB  1 
ATOM   1459 C  CG  . TYR B 2 39  ? 113.325 113.460 111.485 1.00 27.84  ? 39  TYR D CG  1 
ATOM   1460 C  CD1 . TYR B 2 39  ? 112.749 112.508 112.314 1.00 27.84  ? 39  TYR D CD1 1 
ATOM   1461 C  CD2 . TYR B 2 39  ? 114.248 113.033 110.543 1.00 27.84  ? 39  TYR D CD2 1 
ATOM   1462 C  CE1 . TYR B 2 39  ? 113.079 111.173 112.204 1.00 27.84  ? 39  TYR D CE1 1 
ATOM   1463 C  CE2 . TYR B 2 39  ? 114.585 111.701 110.426 1.00 27.84  ? 39  TYR D CE2 1 
ATOM   1464 C  CZ  . TYR B 2 39  ? 113.998 110.776 111.259 1.00 27.84  ? 39  TYR D CZ  1 
ATOM   1465 O  OH  . TYR B 2 39  ? 114.331 109.447 111.145 1.00 27.84  ? 39  TYR D OH  1 
ATOM   1466 N  N   . ALA B 2 40  ? 111.154 117.523 112.215 1.00 31.86  ? 40  ALA D N   1 
ATOM   1467 C  CA  . ALA B 2 40  ? 111.095 118.936 112.567 1.00 31.86  ? 40  ALA D CA  1 
ATOM   1468 C  C   . ALA B 2 40  ? 110.362 119.189 113.875 1.00 31.86  ? 40  ALA D C   1 
ATOM   1469 O  O   . ALA B 2 40  ? 110.718 120.132 114.589 1.00 31.86  ? 40  ALA D O   1 
ATOM   1470 C  CB  . ALA B 2 40  ? 110.431 119.732 111.445 1.00 31.86  ? 40  ALA D CB  1 
ATOM   1471 N  N   . SER B 2 41  ? 109.355 118.382 114.208 1.00 32.33  ? 41  SER D N   1 
ATOM   1472 C  CA  . SER B 2 41  ? 108.658 118.537 115.478 1.00 32.33  ? 41  SER D CA  1 
ATOM   1473 C  C   . SER B 2 41  ? 109.411 117.884 116.629 1.00 32.33  ? 41  SER D C   1 
ATOM   1474 O  O   . SER B 2 41  ? 109.456 118.442 117.734 1.00 32.33  ? 41  SER D O   1 
ATOM   1475 C  CB  . SER B 2 41  ? 107.247 117.954 115.382 1.00 32.33  ? 41  SER D CB  1 
ATOM   1476 O  OG  . SER B 2 41  ? 106.539 118.143 116.595 1.00 32.33  ? 41  SER D OG  1 
ATOM   1477 N  N   . GLU B 2 42  ? 110.013 116.714 116.394 1.00 36.92  ? 42  GLU D N   1 
ATOM   1478 C  CA  . GLU B 2 42  ? 110.797 116.087 117.457 1.00 36.92  ? 42  GLU D CA  1 
ATOM   1479 C  C   . GLU B 2 42  ? 111.994 116.952 117.844 1.00 36.92  ? 42  GLU D C   1 
ATOM   1480 O  O   . GLU B 2 42  ? 112.313 117.088 119.033 1.00 36.92  ? 42  GLU D O   1 
ATOM   1481 C  CB  . GLU B 2 42  ? 111.245 114.689 117.034 1.00 36.92  ? 42  GLU D CB  1 
ATOM   1482 C  CG  . GLU B 2 42  ? 110.134 113.652 117.107 1.00 36.92  ? 42  GLU D CG  1 
ATOM   1483 C  CD  . GLU B 2 42  ? 110.631 112.238 116.881 1.00 36.92  ? 42  GLU D CD  1 
ATOM   1484 O  OE1 . GLU B 2 42  ? 111.848 112.060 116.669 1.00 36.92  ? 42  GLU D OE1 1 
ATOM   1485 O  OE2 . GLU B 2 42  ? 109.803 111.303 116.916 1.00 36.92  ? 42  GLU D OE2 1 
ATOM   1486 N  N   . GLN B 2 43  ? 112.656 117.563 116.856 1.00 39.51  ? 43  GLN D N   1 
ATOM   1487 C  CA  . GLN B 2 43  ? 113.773 118.457 117.144 1.00 39.51  ? 43  GLN D CA  1 
ATOM   1488 C  C   . GLN B 2 43  ? 113.345 119.636 118.001 1.00 39.51  ? 43  GLN D C   1 
ATOM   1489 O  O   . GLN B 2 43  ? 114.049 120.000 118.950 1.00 39.51  ? 43  GLN D O   1 
ATOM   1490 C  CB  . GLN B 2 43  ? 114.392 118.962 115.841 1.00 39.51  ? 43  GLN D CB  1 
ATOM   1491 C  CG  . GLN B 2 43  ? 115.532 119.947 116.036 1.00 39.51  ? 43  GLN D CG  1 
ATOM   1492 C  CD  . GLN B 2 43  ? 116.245 120.277 114.740 1.00 39.51  ? 43  GLN D CD  1 
ATOM   1493 O  OE1 . GLN B 2 43  ? 115.766 119.952 113.654 1.00 39.51  ? 43  GLN D OE1 1 
ATOM   1494 N  NE2 . GLN B 2 43  ? 117.398 120.925 114.848 1.00 39.51  ? 43  GLN D NE2 1 
ATOM   1495 N  N   . ASP B 2 44  ? 112.204 120.247 117.685 1.00 41.55  ? 44  ASP D N   1 
ATOM   1496 C  CA  . ASP B 2 44  ? 111.753 121.400 118.451 1.00 41.55  ? 44  ASP D CA  1 
ATOM   1497 C  C   . ASP B 2 44  ? 111.384 120.969 119.868 1.00 41.55  ? 44  ASP D C   1 
ATOM   1498 O  O   . ASP B 2 44  ? 111.677 121.677 120.835 1.00 41.55  ? 44  ASP D O   1 
ATOM   1499 C  CB  . ASP B 2 44  ? 110.577 122.068 117.720 1.00 41.55  ? 44  ASP D CB  1 
ATOM   1500 C  CG  . ASP B 2 44  ? 109.943 123.227 118.496 1.00 41.55  ? 44  ASP D CG  1 
ATOM   1501 O  OD1 . ASP B 2 44  ? 109.906 123.239 119.740 1.00 41.55  ? 44  ASP D OD1 1 
ATOM   1502 O  OD2 . ASP B 2 44  ? 109.462 124.163 117.825 1.00 41.55  ? 44  ASP D OD2 1 
ATOM   1503 N  N   . GLN B 2 45  ? 110.765 119.795 120.014 1.00 37.67  ? 45  GLN D N   1 
ATOM   1504 C  CA  . GLN B 2 45  ? 110.447 119.306 121.354 1.00 37.67  ? 45  GLN D CA  1 
ATOM   1505 C  C   . GLN B 2 45  ? 111.702 118.992 122.163 1.00 37.67  ? 45  GLN D C   1 
ATOM   1506 O  O   . GLN B 2 45  ? 111.681 119.082 123.395 1.00 37.67  ? 45  GLN D O   1 
ATOM   1507 C  CB  . GLN B 2 45  ? 109.559 118.065 121.273 1.00 37.67  ? 45  GLN D CB  1 
ATOM   1508 C  CG  . GLN B 2 45  ? 108.967 117.634 122.610 1.00 37.67  ? 45  GLN D CG  1 
ATOM   1509 C  CD  . GLN B 2 45  ? 107.831 118.524 123.070 1.00 37.67  ? 45  GLN D CD  1 
ATOM   1510 O  OE1 . GLN B 2 45  ? 107.397 119.421 122.349 1.00 37.67  ? 45  GLN D OE1 1 
ATOM   1511 N  NE2 . GLN B 2 45  ? 107.346 118.283 124.282 1.00 37.67  ? 45  GLN D NE2 1 
ATOM   1512 N  N   . ALA B 2 46  ? 112.797 118.619 121.498 1.00 34.70  ? 46  ALA D N   1 
ATOM   1513 C  CA  . ALA B 2 46  ? 113.977 118.163 122.227 1.00 34.70  ? 46  ALA D CA  1 
ATOM   1514 C  C   . ALA B 2 46  ? 114.814 119.298 122.813 1.00 34.70  ? 46  ALA D C   1 
ATOM   1515 O  O   . ALA B 2 46  ? 115.758 119.020 123.558 1.00 34.70  ? 46  ALA D O   1 
ATOM   1516 C  CB  . ALA B 2 46  ? 114.852 117.301 121.318 1.00 34.70  ? 46  ALA D CB  1 
ATOM   1517 N  N   . GLU B 2 47  ? 114.507 120.563 122.507 1.00 43.39  ? 47  GLU D N   1 
ATOM   1518 C  CA  . GLU B 2 47  ? 115.347 121.650 123.012 1.00 43.39  ? 47  GLU D CA  1 
ATOM   1519 C  C   . GLU B 2 47  ? 115.103 121.939 124.489 1.00 43.39  ? 47  GLU D C   1 
ATOM   1520 O  O   . GLU B 2 47  ? 115.894 122.661 125.106 1.00 43.39  ? 47  GLU D O   1 
ATOM   1521 C  CB  . GLU B 2 47  ? 115.160 122.908 122.147 1.00 43.39  ? 47  GLU D CB  1 
ATOM   1522 C  CG  . GLU B 2 47  ? 113.754 123.513 122.087 1.00 43.39  ? 47  GLU D CG  1 
ATOM   1523 C  CD  . GLU B 2 47  ? 113.342 124.300 123.319 1.00 43.39  ? 47  GLU D CD  1 
ATOM   1524 O  OE1 . GLU B 2 47  ? 112.148 124.656 123.413 1.00 43.39  ? 47  GLU D OE1 1 
ATOM   1525 O  OE2 . GLU B 2 47  ? 114.208 124.616 124.159 1.00 43.39  ? 47  GLU D OE2 1 
ATOM   1526 N  N   . LEU B 2 48  ? 114.031 121.393 125.066 1.00 32.36  ? 48  LEU D N   1 
ATOM   1527 C  CA  . LEU B 2 48  ? 113.823 121.507 126.505 1.00 32.36  ? 48  LEU D CA  1 
ATOM   1528 C  C   . LEU B 2 48  ? 114.955 120.847 127.284 1.00 32.36  ? 48  LEU D C   1 
ATOM   1529 O  O   . LEU B 2 48  ? 115.339 121.332 128.357 1.00 32.36  ? 48  LEU D O   1 
ATOM   1530 C  CB  . LEU B 2 48  ? 112.473 120.894 126.875 1.00 32.36  ? 48  LEU D CB  1 
ATOM   1531 C  CG  . LEU B 2 48  ? 111.979 121.014 128.316 1.00 32.36  ? 48  LEU D CG  1 
ATOM   1532 C  CD1 . LEU B 2 48  ? 110.505 121.384 128.332 1.00 32.36  ? 48  LEU D CD1 1 
ATOM   1533 C  CD2 . LEU B 2 48  ? 112.204 119.705 129.046 1.00 32.36  ? 48  LEU D CD2 1 
ATOM   1534 N  N   . TYR B 2 49  ? 115.505 119.750 126.759 1.00 35.32  ? 49  TYR D N   1 
ATOM   1535 C  CA  . TYR B 2 49  ? 116.653 119.113 127.396 1.00 35.32  ? 49  TYR D CA  1 
ATOM   1536 C  C   . TYR B 2 49  ? 117.850 120.054 127.432 1.00 35.32  ? 49  TYR D C   1 
ATOM   1537 O  O   . TYR B 2 49  ? 118.522 120.180 128.462 1.00 35.32  ? 49  TYR D O   1 
ATOM   1538 C  CB  . TYR B 2 49  ? 117.011 117.823 126.660 1.00 35.32  ? 49  TYR D CB  1 
ATOM   1539 C  CG  . TYR B 2 49  ? 118.335 117.223 127.076 1.00 35.32  ? 49  TYR D CG  1 
ATOM   1540 C  CD1 . TYR B 2 49  ? 118.575 116.860 128.393 1.00 35.32  ? 49  TYR D CD1 1 
ATOM   1541 C  CD2 . TYR B 2 49  ? 119.348 117.027 126.149 1.00 35.32  ? 49  TYR D CD2 1 
ATOM   1542 C  CE1 . TYR B 2 49  ? 119.784 116.311 128.773 1.00 35.32  ? 49  TYR D CE1 1 
ATOM   1543 C  CE2 . TYR B 2 49  ? 120.559 116.479 126.519 1.00 35.32  ? 49  TYR D CE2 1 
ATOM   1544 C  CZ  . TYR B 2 49  ? 120.772 116.124 127.831 1.00 35.32  ? 49  TYR D CZ  1 
ATOM   1545 O  OH  . TYR B 2 49  ? 121.979 115.580 128.202 1.00 35.32  ? 49  TYR D OH  1 
ATOM   1546 N  N   . LYS B 2 50  ? 118.132 120.725 126.313 1.00 37.71  ? 50  LYS D N   1 
ATOM   1547 C  CA  . LYS B 2 50  ? 119.237 121.678 126.281 1.00 37.71  ? 50  LYS D CA  1 
ATOM   1548 C  C   . LYS B 2 50  ? 118.987 122.838 127.233 1.00 37.71  ? 50  LYS D C   1 
ATOM   1549 O  O   . LYS B 2 50  ? 119.910 123.309 127.911 1.00 37.71  ? 50  LYS D O   1 
ATOM   1550 C  CB  . LYS B 2 50  ? 119.449 122.196 124.859 1.00 37.71  ? 50  LYS D CB  1 
ATOM   1551 C  CG  . LYS B 2 50  ? 119.759 121.119 123.835 1.00 37.71  ? 50  LYS D CG  1 
ATOM   1552 C  CD  . LYS B 2 50  ? 119.951 121.720 122.453 1.00 37.71  ? 50  LYS D CD  1 
ATOM   1553 C  CE  . LYS B 2 50  ? 120.001 120.641 121.388 1.00 37.71  ? 50  LYS D CE  1 
ATOM   1554 N  NZ  . LYS B 2 50  ? 121.197 119.771 121.545 1.00 37.71  ? 50  LYS D NZ  1 
ATOM   1555 N  N   . PHE B 2 51  ? 117.743 123.320 127.287 1.00 40.91  ? 51  PHE D N   1 
ATOM   1556 C  CA  . PHE B 2 51  ? 117.416 124.418 128.191 1.00 40.91  ? 51  PHE D CA  1 
ATOM   1557 C  C   . PHE B 2 51  ? 117.672 124.027 129.640 1.00 40.91  ? 51  PHE D C   1 
ATOM   1558 O  O   . PHE B 2 51  ? 118.296 124.779 130.396 1.00 40.91  ? 51  PHE D O   1 
ATOM   1559 C  CB  . PHE B 2 51  ? 115.961 124.846 127.998 1.00 40.91  ? 51  PHE D CB  1 
ATOM   1560 C  CG  . PHE B 2 51  ? 115.398 125.613 129.159 1.00 40.91  ? 51  PHE D CG  1 
ATOM   1561 C  CD1 . PHE B 2 51  ? 115.902 126.857 129.495 1.00 40.91  ? 51  PHE D CD1 1 
ATOM   1562 C  CD2 . PHE B 2 51  ? 114.368 125.089 129.917 1.00 40.91  ? 51  PHE D CD2 1 
ATOM   1563 C  CE1 . PHE B 2 51  ? 115.386 127.563 130.563 1.00 40.91  ? 51  PHE D CE1 1 
ATOM   1564 C  CE2 . PHE B 2 51  ? 113.849 125.790 130.987 1.00 40.91  ? 51  PHE D CE2 1 
ATOM   1565 C  CZ  . PHE B 2 51  ? 114.359 127.029 131.310 1.00 40.91  ? 51  PHE D CZ  1 
ATOM   1566 N  N   . PHE B 2 52  ? 117.210 122.842 130.044 1.00 38.70  ? 52  PHE D N   1 
ATOM   1567 C  CA  . PHE B 2 52  ? 117.461 122.385 131.409 1.00 38.70  ? 52  PHE D CA  1 
ATOM   1568 C  C   . PHE B 2 52  ? 118.952 122.198 131.663 1.00 38.70  ? 52  PHE D C   1 
ATOM   1569 O  O   . PHE B 2 52  ? 119.469 122.598 132.715 1.00 38.70  ? 52  PHE D O   1 
ATOM   1570 C  CB  . PHE B 2 52  ? 116.713 121.082 131.676 1.00 38.70  ? 52  PHE D CB  1 
ATOM   1571 C  CG  . PHE B 2 52  ? 115.370 121.272 132.312 1.00 38.70  ? 52  PHE D CG  1 
ATOM   1572 C  CD1 . PHE B 2 52  ? 115.262 121.607 133.647 1.00 38.70  ? 52  PHE D CD1 1 
ATOM   1573 C  CD2 . PHE B 2 52  ? 114.215 121.101 131.574 1.00 38.70  ? 52  PHE D CD2 1 
ATOM   1574 C  CE1 . PHE B 2 52  ? 114.026 121.774 134.231 1.00 38.70  ? 52  PHE D CE1 1 
ATOM   1575 C  CE2 . PHE B 2 52  ? 112.978 121.267 132.152 1.00 38.70  ? 52  PHE D CE2 1 
ATOM   1576 C  CZ  . PHE B 2 52  ? 112.883 121.602 133.482 1.00 38.70  ? 52  PHE D CZ  1 
ATOM   1577 N  N   . ASN B 2 53  ? 119.660 121.596 130.705 1.00 44.59  ? 53  ASN D N   1 
ATOM   1578 C  CA  . ASN B 2 53  ? 121.077 121.305 130.862 1.00 44.59  ? 53  ASN D CA  1 
ATOM   1579 C  C   . ASN B 2 53  ? 121.919 122.560 131.026 1.00 44.59  ? 53  ASN D C   1 
ATOM   1580 O  O   . ASN B 2 53  ? 122.836 122.562 131.853 1.00 44.59  ? 53  ASN D O   1 
ATOM   1581 C  CB  . ASN B 2 53  ? 121.573 120.498 129.662 1.00 44.59  ? 53  ASN D CB  1 
ATOM   1582 C  CG  . ASN B 2 53  ? 122.675 119.525 130.028 1.00 44.59  ? 53  ASN D CG  1 
ATOM   1583 O  OD1 . ASN B 2 53  ? 122.661 118.931 131.105 1.00 44.59  ? 53  ASN D OD1 1 
ATOM   1584 N  ND2 . ASN B 2 53  ? 123.635 119.353 129.128 1.00 44.59  ? 53  ASN D ND2 1 
ATOM   1585 N  N   . ASP B 2 54  ? 121.637 123.622 130.269 1.00 50.81  ? 54  ASP D N   1 
ATOM   1586 C  CA  . ASP B 2 54  ? 122.372 124.867 130.437 1.00 50.81  ? 54  ASP D CA  1 
ATOM   1587 C  C   . ASP B 2 54  ? 121.817 125.786 131.519 1.00 50.81  ? 54  ASP D C   1 
ATOM   1588 O  O   . ASP B 2 54  ? 122.531 126.704 131.936 1.00 50.81  ? 54  ASP D O   1 
ATOM   1589 C  CB  . ASP B 2 54  ? 122.487 125.617 129.093 1.00 50.81  ? 54  ASP D CB  1 
ATOM   1590 C  CG  . ASP B 2 54  ? 121.234 126.408 128.708 1.00 50.81  ? 54  ASP D CG  1 
ATOM   1591 O  OD1 . ASP B 2 54  ? 120.261 126.509 129.480 1.00 50.81  ? 54  ASP D OD1 1 
ATOM   1592 O  OD2 . ASP B 2 54  ? 121.238 126.952 127.586 1.00 50.81  ? 54  ASP D OD2 1 
ATOM   1593 N  N   . LEU B 2 55  ? 120.583 125.577 131.987 1.00 45.67  ? 55  LEU D N   1 
ATOM   1594 C  CA  . LEU B 2 55  ? 120.120 126.292 133.172 1.00 45.67  ? 55  LEU D CA  1 
ATOM   1595 C  C   . LEU B 2 55  ? 120.765 125.727 134.427 1.00 45.67  ? 55  LEU D C   1 
ATOM   1596 O  O   . LEU B 2 55  ? 121.025 126.461 135.388 1.00 45.67  ? 55  LEU D O   1 
ATOM   1597 C  CB  . LEU B 2 55  ? 118.597 126.223 133.269 1.00 45.67  ? 55  LEU D CB  1 
ATOM   1598 C  CG  . LEU B 2 55  ? 117.966 126.764 134.553 1.00 45.67  ? 55  LEU D CG  1 
ATOM   1599 C  CD1 . LEU B 2 55  ? 118.136 128.269 134.637 1.00 45.67  ? 55  LEU D CD1 1 
ATOM   1600 C  CD2 . LEU B 2 55  ? 116.499 126.386 134.630 1.00 45.67  ? 55  LEU D CD2 1 
ATOM   1601 N  N   . ILE B 2 56  ? 121.031 124.419 134.437 1.00 49.99  ? 56  ILE D N   1 
ATOM   1602 C  CA  . ILE B 2 56  ? 121.762 123.818 135.545 1.00 49.99  ? 56  ILE D CA  1 
ATOM   1603 C  C   . ILE B 2 56  ? 123.155 124.417 135.672 1.00 49.99  ? 56  ILE D C   1 
ATOM   1604 O  O   . ILE B 2 56  ? 123.607 124.706 136.786 1.00 49.99  ? 56  ILE D O   1 
ATOM   1605 C  CB  . ILE B 2 56  ? 121.825 122.287 135.368 1.00 49.99  ? 56  ILE D CB  1 
ATOM   1606 C  CG1 . ILE B 2 56  ? 120.472 121.659 135.704 1.00 49.99  ? 56  ILE D CG1 1 
ATOM   1607 C  CG2 . ILE B 2 56  ? 122.922 121.686 136.233 1.00 49.99  ? 56  ILE D CG2 1 
ATOM   1608 C  CD1 . ILE B 2 56  ? 120.472 120.150 135.663 1.00 49.99  ? 56  ILE D CD1 1 
ATOM   1609 N  N   . LYS B 2 57  ? 123.846 124.624 134.551 1.00 53.46  ? 57  LYS D N   1 
ATOM   1610 C  CA  . LYS B 2 57  ? 125.196 125.175 134.545 1.00 53.46  ? 57  LYS D CA  1 
ATOM   1611 C  C   . LYS B 2 57  ? 125.243 126.611 135.063 1.00 53.46  ? 57  LYS D C   1 
ATOM   1612 O  O   . LYS B 2 57  ? 126.134 126.959 135.845 1.00 53.46  ? 57  LYS D O   1 
ATOM   1613 C  CB  . LYS B 2 57  ? 125.777 125.102 133.128 1.00 53.46  ? 57  LYS D CB  1 
ATOM   1614 C  CG  . LYS B 2 57  ? 126.695 126.257 132.759 1.00 53.46  ? 57  LYS D CG  1 
ATOM   1615 C  CD  . LYS B 2 57  ? 127.593 125.896 131.588 1.00 53.46  ? 57  LYS D CD  1 
ATOM   1616 C  CE  . LYS B 2 57  ? 128.392 124.634 131.870 1.00 53.46  ? 57  LYS D CE  1 
ATOM   1617 N  NZ  . LYS B 2 57  ? 129.416 124.379 130.820 1.00 53.46  ? 57  LYS D NZ  1 
ATOM   1618 N  N   . HIS B 2 58  ? 124.295 127.453 134.643 1.00 54.30  ? 58  HIS D N   1 
ATOM   1619 C  CA  . HIS B 2 58  ? 124.343 128.863 135.021 1.00 54.30  ? 58  HIS D CA  1 
ATOM   1620 C  C   . HIS B 2 58  ? 124.081 129.056 136.509 1.00 54.30  ? 58  HIS D C   1 
ATOM   1621 O  O   . HIS B 2 58  ? 124.828 129.770 137.188 1.00 54.30  ? 58  HIS D O   1 
ATOM   1622 C  CB  . HIS B 2 58  ? 123.339 129.664 134.194 1.00 54.30  ? 58  HIS D CB  1 
ATOM   1623 C  CG  . HIS B 2 58  ? 123.787 129.928 132.790 1.00 54.30  ? 58  HIS D CG  1 
ATOM   1624 N  ND1 . HIS B 2 58  ? 124.718 129.142 132.146 1.00 54.30  ? 58  HIS D ND1 1 
ATOM   1625 C  CD2 . HIS B 2 58  ? 123.432 130.891 131.908 1.00 54.30  ? 58  HIS D CD2 1 
ATOM   1626 C  CE1 . HIS B 2 58  ? 124.917 129.609 130.926 1.00 54.30  ? 58  HIS D CE1 1 
ATOM   1627 N  NE2 . HIS B 2 58  ? 124.149 130.670 130.757 1.00 54.30  ? 58  HIS D NE2 1 
ATOM   1628 N  N   . MET B 2 59  ? 123.032 128.433 137.034 1.00 61.67  ? 59  MET D N   1 
ATOM   1629 C  CA  . MET B 2 59  ? 122.685 128.591 138.435 1.00 61.67  ? 59  MET D CA  1 
ATOM   1630 C  C   . MET B 2 59  ? 123.711 127.900 139.327 1.00 61.67  ? 59  MET D C   1 
ATOM   1631 O  O   . MET B 2 59  ? 124.337 126.915 138.926 1.00 61.67  ? 59  MET D O   1 
ATOM   1632 C  CB  . MET B 2 59  ? 121.293 128.027 138.698 1.00 61.67  ? 59  MET D CB  1 
ATOM   1633 C  CG  . MET B 2 59  ? 120.199 128.683 137.874 1.00 61.67  ? 59  MET D CG  1 
ATOM   1634 S  SD  . MET B 2 59  ? 119.780 130.335 138.460 1.00 61.67  ? 59  MET D SD  1 
ATOM   1635 C  CE  . MET B 2 59  ? 119.632 131.215 136.908 1.00 61.67  ? 59  MET D CE  1 
ATOM   1636 N  N   . PRO B 2 60  ? 123.915 128.410 140.542 1.00 76.72  ? 60  PRO D N   1 
ATOM   1637 C  CA  . PRO B 2 60  ? 124.877 127.780 141.453 1.00 76.72  ? 60  PRO D CA  1 
ATOM   1638 C  C   . PRO B 2 60  ? 124.479 126.351 141.786 1.00 76.72  ? 60  PRO D C   1 
ATOM   1639 O  O   . PRO B 2 60  ? 123.297 126.012 141.868 1.00 76.72  ? 60  PRO D O   1 
ATOM   1640 C  CB  . PRO B 2 60  ? 124.835 128.677 142.698 1.00 76.72  ? 60  PRO D CB  1 
ATOM   1641 C  CG  . PRO B 2 60  ? 123.578 129.485 142.562 1.00 76.72  ? 60  PRO D CG  1 
ATOM   1642 C  CD  . PRO B 2 60  ? 123.368 129.659 141.096 1.00 76.72  ? 60  PRO D CD  1 
ATOM   1643 N  N   . GLN B 2 61  ? 125.491 125.510 141.974 1.00 85.63  ? 61  GLN D N   1 
ATOM   1644 C  CA  . GLN B 2 61  ? 125.279 124.103 142.289 1.00 85.63  ? 61  GLN D CA  1 
ATOM   1645 C  C   . GLN B 2 61  ? 124.677 123.929 143.680 1.00 85.63  ? 61  GLN D C   1 
ATOM   1646 O  O   . GLN B 2 61  ? 124.145 122.870 144.012 1.00 85.63  ? 61  GLN D O   1 
ATOM   1647 C  CB  . GLN B 2 61  ? 126.596 123.332 142.185 1.00 85.63  ? 61  GLN D CB  1 
ATOM   1648 C  CG  . GLN B 2 61  ? 127.662 123.797 143.164 1.00 85.63  ? 61  GLN D CG  1 
ATOM   1649 C  CD  . GLN B 2 61  ? 129.023 123.198 142.873 1.00 85.63  ? 61  GLN D CD  1 
ATOM   1650 O  OE1 . GLN B 2 61  ? 129.215 122.524 141.861 1.00 85.63  ? 61  GLN D OE1 1 
ATOM   1651 N  NE2 . GLN B 2 61  ? 129.979 123.442 143.763 1.00 85.63  ? 61  GLN D NE2 1 
ATOM   1652 N  N   . ASP B 2 80  ? 97.613  101.393 147.872 1.00 124.43 ? 80  ASP D N   1 
ATOM   1653 C  CA  . ASP B 2 80  ? 96.437  100.554 148.074 1.00 124.43 ? 80  ASP D CA  1 
ATOM   1654 C  C   . ASP B 2 80  ? 95.238  101.393 148.503 1.00 124.43 ? 80  ASP D C   1 
ATOM   1655 O  O   . ASP B 2 80  ? 94.165  100.862 148.787 1.00 124.43 ? 80  ASP D O   1 
ATOM   1656 C  CB  . ASP B 2 80  ? 96.725  99.470  149.114 1.00 124.43 ? 80  ASP D CB  1 
ATOM   1657 C  CG  . ASP B 2 80  ? 95.841  98.251  148.945 1.00 124.43 ? 80  ASP D CG  1 
ATOM   1658 O  OD1 . ASP B 2 80  ? 95.386  97.997  147.810 1.00 124.43 ? 80  ASP D OD1 1 
ATOM   1659 O  OD2 . ASP B 2 80  ? 95.602  97.544  149.947 1.00 124.43 ? 80  ASP D OD2 1 
ATOM   1660 N  N   . LYS B 2 81  ? 95.432  102.709 148.547 1.00 122.13 ? 81  LYS D N   1 
ATOM   1661 C  CA  . LYS B 2 81  ? 94.357  103.612 148.936 1.00 122.13 ? 81  LYS D CA  1 
ATOM   1662 C  C   . LYS B 2 81  ? 93.266  103.634 147.873 1.00 122.13 ? 81  LYS D C   1 
ATOM   1663 O  O   . LYS B 2 81  ? 93.544  103.634 146.670 1.00 122.13 ? 81  LYS D O   1 
ATOM   1664 C  CB  . LYS B 2 81  ? 94.905  105.022 149.156 1.00 122.13 ? 81  LYS D CB  1 
ATOM   1665 C  CG  . LYS B 2 81  ? 96.106  105.081 150.085 1.00 122.13 ? 81  LYS D CG  1 
ATOM   1666 C  CD  . LYS B 2 81  ? 96.689  106.483 150.143 1.00 122.13 ? 81  LYS D CD  1 
ATOM   1667 C  CE  . LYS B 2 81  ? 97.994  106.504 150.924 1.00 122.13 ? 81  LYS D CE  1 
ATOM   1668 N  NZ  . LYS B 2 81  ? 98.635  107.848 150.900 1.00 122.13 ? 81  LYS D NZ  1 
ATOM   1669 N  N   . ASP B 2 82  ? 92.015  103.655 148.324 1.00 122.59 ? 82  ASP D N   1 
ATOM   1670 C  CA  . ASP B 2 82  ? 90.884  103.704 147.412 1.00 122.59 ? 82  ASP D CA  1 
ATOM   1671 C  C   . ASP B 2 82  ? 90.492  105.148 147.126 1.00 122.59 ? 82  ASP D C   1 
ATOM   1672 O  O   . ASP B 2 82  ? 90.128  105.908 148.028 1.00 122.59 ? 82  ASP D O   1 
ATOM   1673 C  CB  . ASP B 2 82  ? 89.691  102.943 147.992 1.00 122.59 ? 82  ASP D CB  1 
ATOM   1674 C  CG  . ASP B 2 82  ? 90.000  101.481 148.245 1.00 122.59 ? 82  ASP D CG  1 
ATOM   1675 O  OD1 . ASP B 2 82  ? 90.763  100.887 147.454 1.00 122.59 ? 82  ASP D OD1 1 
ATOM   1676 O  OD2 . ASP B 2 82  ? 89.481  100.925 149.235 1.00 122.59 ? 82  ASP D OD2 1 
ATOM   1677 N  N   . ASP B 2 83  ? 90.574  105.524 145.851 1.00 107.82 ? 83  ASP D N   1 
ATOM   1678 C  CA  . ASP B 2 83  ? 90.270  106.888 145.438 1.00 107.82 ? 83  ASP D CA  1 
ATOM   1679 C  C   . ASP B 2 83  ? 89.364  106.899 144.212 1.00 107.82 ? 83  ASP D C   1 
ATOM   1680 O  O   . ASP B 2 83  ? 88.696  107.901 143.936 1.00 107.82 ? 83  ASP D O   1 
ATOM   1681 C  CB  . ASP B 2 83  ? 91.562  107.656 145.153 1.00 107.82 ? 83  ASP D CB  1 
ATOM   1682 C  CG  . ASP B 2 83  ? 91.316  109.119 144.845 1.00 107.82 ? 83  ASP D CG  1 
ATOM   1683 O  OD1 . ASP B 2 83  ? 90.423  109.720 145.479 1.00 107.82 ? 83  ASP D OD1 1 
ATOM   1684 O  OD2 . ASP B 2 83  ? 92.014  109.668 143.967 1.00 107.82 ? 83  ASP D OD2 1 
ATOM   1685 N  N   . LEU B 2 84  ? 89.337  105.791 143.475 1.00 94.88  ? 84  LEU D N   1 
ATOM   1686 C  CA  . LEU B 2 84  ? 88.561  105.729 142.244 1.00 94.88  ? 84  LEU D CA  1 
ATOM   1687 C  C   . LEU B 2 84  ? 87.071  105.848 142.540 1.00 94.88  ? 84  LEU D C   1 
ATOM   1688 O  O   . LEU B 2 84  ? 86.578  105.348 143.555 1.00 94.88  ? 84  LEU D O   1 
ATOM   1689 C  CB  . LEU B 2 84  ? 88.850  104.424 141.499 1.00 94.88  ? 84  LEU D CB  1 
ATOM   1690 C  CG  . LEU B 2 84  ? 90.224  104.274 140.835 1.00 94.88  ? 84  LEU D CG  1 
ATOM   1691 C  CD1 . LEU B 2 84  ? 90.627  105.559 140.124 1.00 94.88  ? 84  LEU D CD1 1 
ATOM   1692 C  CD2 . LEU B 2 84  ? 91.295  103.843 141.830 1.00 94.88  ? 84  LEU D CD2 1 
ATOM   1693 N  N   . VAL B 2 85  ? 86.352  106.518 141.642 1.00 91.66  ? 85  VAL D N   1 
ATOM   1694 C  CA  . VAL B 2 85  ? 84.925  106.768 141.796 1.00 91.66  ? 85  VAL D CA  1 
ATOM   1695 C  C   . VAL B 2 85  ? 84.184  106.153 140.618 1.00 91.66  ? 85  VAL D C   1 
ATOM   1696 O  O   . VAL B 2 85  ? 84.792  105.690 139.648 1.00 91.66  ? 85  VAL D O   1 
ATOM   1697 C  CB  . VAL B 2 85  ? 84.616  108.278 141.909 1.00 91.66  ? 85  VAL D CB  1 
ATOM   1698 C  CG1 . VAL B 2 85  ? 85.619  108.959 142.825 1.00 91.66  ? 85  VAL D CG1 1 
ATOM   1699 C  CG2 . VAL B 2 85  ? 84.622  108.927 140.534 1.00 91.66  ? 85  VAL D CG2 1 
ATOM   1700 N  N   . GLU B 2 86  ? 82.855  106.145 140.714 1.00 99.95  ? 86  GLU D N   1 
ATOM   1701 C  CA  . GLU B 2 86  ? 82.029  105.599 139.646 1.00 99.95  ? 86  GLU D CA  1 
ATOM   1702 C  C   . GLU B 2 86  ? 82.181  106.435 138.381 1.00 99.95  ? 86  GLU D C   1 
ATOM   1703 O  O   . GLU B 2 86  ? 82.357  107.656 138.446 1.00 99.95  ? 86  GLU D O   1 
ATOM   1704 C  CB  . GLU B 2 86  ? 80.564  105.551 140.084 1.00 99.95  ? 86  GLU D CB  1 
ATOM   1705 C  CG  . GLU B 2 86  ? 79.646  104.805 139.125 1.00 99.95  ? 86  GLU D CG  1 
ATOM   1706 C  CD  . GLU B 2 86  ? 79.898  103.308 139.113 1.00 99.95  ? 86  GLU D CD  1 
ATOM   1707 O  OE1 . GLU B 2 86  ? 80.522  102.797 140.067 1.00 99.95  ? 86  GLU D OE1 1 
ATOM   1708 O  OE2 . GLU B 2 86  ? 79.474  102.641 138.146 1.00 99.95  ? 86  GLU D OE2 1 
ATOM   1709 N  N   . GLU B 2 87  ? 82.112  105.774 137.229 1.00 92.54  ? 87  GLU D N   1 
ATOM   1710 C  CA  . GLU B 2 87  ? 82.383  106.445 135.968 1.00 92.54  ? 87  GLU D CA  1 
ATOM   1711 C  C   . GLU B 2 87  ? 81.093  106.704 135.193 1.00 92.54  ? 87  GLU D C   1 
ATOM   1712 O  O   . GLU B 2 87  ? 80.218  105.842 135.073 1.00 92.54  ? 87  GLU D O   1 
ATOM   1713 C  CB  . GLU B 2 87  ? 83.347  105.613 135.120 1.00 92.54  ? 87  GLU D CB  1 
ATOM   1714 C  CG  . GLU B 2 87  ? 83.929  106.334 133.906 1.00 92.54  ? 87  GLU D CG  1 
ATOM   1715 C  CD  . GLU B 2 87  ? 84.531  107.696 134.224 1.00 92.54  ? 87  GLU D CD  1 
ATOM   1716 O  OE1 . GLU B 2 87  ? 84.930  107.938 135.384 1.00 92.54  ? 87  GLU D OE1 1 
ATOM   1717 O  OE2 . GLU B 2 87  ? 84.602  108.534 133.302 1.00 92.54  ? 87  GLU D OE2 1 
ATOM   1718 N  N   . PHE B 2 88  ? 80.990  107.918 134.660 1.00 107.04 ? 88  PHE D N   1 
ATOM   1719 C  CA  . PHE B 2 88  ? 79.856  108.309 133.837 1.00 107.04 ? 88  PHE D CA  1 
ATOM   1720 C  C   . PHE B 2 88  ? 79.892  107.598 132.489 1.00 107.04 ? 88  PHE D C   1 
ATOM   1721 O  O   . PHE B 2 88  ? 80.960  107.304 131.944 1.00 107.04 ? 88  PHE D O   1 
ATOM   1722 C  CB  . PHE B 2 88  ? 79.852  109.824 133.626 1.00 107.04 ? 88  PHE D CB  1 
ATOM   1723 C  CG  . PHE B 2 88  ? 78.659  110.332 132.865 1.00 107.04 ? 88  PHE D CG  1 
ATOM   1724 C  CD1 . PHE B 2 88  ? 77.443  110.523 133.500 1.00 107.04 ? 88  PHE D CD1 1 
ATOM   1725 C  CD2 . PHE B 2 88  ? 78.758  110.628 131.515 1.00 107.04 ? 88  PHE D CD2 1 
ATOM   1726 C  CE1 . PHE B 2 88  ? 76.347  110.994 132.800 1.00 107.04 ? 88  PHE D CE1 1 
ATOM   1727 C  CE2 . PHE B 2 88  ? 77.666  111.098 130.811 1.00 107.04 ? 88  PHE D CE2 1 
ATOM   1728 C  CZ  . PHE B 2 88  ? 76.459  111.281 131.454 1.00 107.04 ? 88  PHE D CZ  1 
ATOM   1729 N  N   . GLY B 2 89  ? 78.706  107.323 131.953 1.00 107.44 ? 89  GLY D N   1 
ATOM   1730 C  CA  . GLY B 2 89  ? 78.602  106.709 130.646 1.00 107.44 ? 89  GLY D CA  1 
ATOM   1731 C  C   . GLY B 2 89  ? 78.539  105.190 130.700 1.00 107.44 ? 89  GLY D C   1 
ATOM   1732 O  O   . GLY B 2 89  ? 78.455  104.565 131.758 1.00 107.44 ? 89  GLY D O   1 
ATOM   1733 N  N   . ASP B 2 90  ? 78.577  104.601 129.506 1.00 96.69  ? 90  ASP D N   1 
ATOM   1734 C  CA  . ASP B 2 90  ? 78.512  103.153 129.377 1.00 96.69  ? 90  ASP D CA  1 
ATOM   1735 C  C   . ASP B 2 90  ? 79.765  102.533 129.983 1.00 96.69  ? 90  ASP D C   1 
ATOM   1736 O  O   . ASP B 2 90  ? 80.874  103.051 129.826 1.00 96.69  ? 90  ASP D O   1 
ATOM   1737 C  CB  . ASP B 2 90  ? 78.358  102.768 127.900 1.00 96.69  ? 90  ASP D CB  1 
ATOM   1738 C  CG  . ASP B 2 90  ? 78.355  101.254 127.654 1.00 96.69  ? 90  ASP D CG  1 
ATOM   1739 O  OD1 . ASP B 2 90  ? 77.656  100.829 126.710 1.00 96.69  ? 90  ASP D OD1 1 
ATOM   1740 O  OD2 . ASP B 2 90  ? 79.038  100.485 128.362 1.00 96.69  ? 90  ASP D OD2 1 
ATOM   1741 N  N   . ILE B 2 91  ? 79.582  101.416 130.680 1.00 82.50  ? 91  ILE D N   1 
ATOM   1742 C  CA  . ILE B 2 91  ? 80.669  100.736 131.373 1.00 82.50  ? 91  ILE D CA  1 
ATOM   1743 C  C   . ILE B 2 91  ? 80.572  99.241  131.094 1.00 82.50  ? 91  ILE D C   1 
ATOM   1744 O  O   . ILE B 2 91  ? 79.479  98.666  131.097 1.00 82.50  ? 91  ILE D O   1 
ATOM   1745 C  CB  . ILE B 2 91  ? 80.639  101.028 132.889 1.00 82.50  ? 91  ILE D CB  1 
ATOM   1746 C  CG1 . ILE B 2 91  ? 81.755  100.267 133.601 1.00 82.50  ? 91  ILE D CG1 1 
ATOM   1747 C  CG2 . ILE B 2 91  ? 79.277  100.693 133.481 1.00 82.50  ? 91  ILE D CG2 1 
ATOM   1748 C  CD1 . ILE B 2 91  ? 83.130  100.708 133.178 1.00 82.50  ? 91  ILE D CD1 1 
ATOM   1749 N  N   . VAL B 2 92  ? 81.718  98.618  130.837 1.00 79.12  ? 92  VAL D N   1 
ATOM   1750 C  CA  . VAL B 2 92  ? 81.770  97.186  130.560 1.00 79.12  ? 92  VAL D CA  1 
ATOM   1751 C  C   . VAL B 2 92  ? 81.946  96.432  131.871 1.00 79.12  ? 92  VAL D C   1 
ATOM   1752 O  O   . VAL B 2 92  ? 82.782  96.797  132.706 1.00 79.12  ? 92  VAL D O   1 
ATOM   1753 C  CB  . VAL B 2 92  ? 82.901  96.866  129.569 1.00 79.12  ? 92  VAL D CB  1 
ATOM   1754 C  CG1 . VAL B 2 92  ? 83.417  95.454  129.774 1.00 79.12  ? 92  VAL D CG1 1 
ATOM   1755 C  CG2 . VAL B 2 92  ? 82.413  97.051  128.145 1.00 79.12  ? 92  VAL D CG2 1 
ATOM   1756 N  N   . ASN B 2 93  ? 81.155  95.375  132.055 1.00 79.76  ? 93  ASN D N   1 
ATOM   1757 C  CA  . ASN B 2 93  ? 81.133  94.638  133.312 1.00 79.76  ? 93  ASN D CA  1 
ATOM   1758 C  C   . ASN B 2 93  ? 82.122  93.477  133.317 1.00 79.76  ? 93  ASN D C   1 
ATOM   1759 O  O   . ASN B 2 93  ? 81.905  92.478  134.010 1.00 79.76  ? 93  ASN D O   1 
ATOM   1760 C  CB  . ASN B 2 93  ? 79.720  94.125  133.597 1.00 79.76  ? 93  ASN D CB  1 
ATOM   1761 C  CG  . ASN B 2 93  ? 79.270  93.075  132.601 1.00 79.76  ? 93  ASN D CG  1 
ATOM   1762 O  OD1 . ASN B 2 93  ? 79.707  93.065  131.451 1.00 79.76  ? 93  ASN D OD1 1 
ATOM   1763 N  ND2 . ASN B 2 93  ? 78.391  92.181  133.040 1.00 79.76  ? 93  ASN D ND2 1 
ATOM   1764 N  N   . ALA B 2 94  ? 83.201  93.592  132.547 1.00 70.60  ? 94  ALA D N   1 
ATOM   1765 C  CA  . ALA B 2 94  ? 84.218  92.549  132.531 1.00 70.60  ? 94  ALA D CA  1 
ATOM   1766 C  C   . ALA B 2 94  ? 84.882  92.432  133.896 1.00 70.60  ? 94  ALA D C   1 
ATOM   1767 O  O   . ALA B 2 94  ? 85.104  93.431  134.586 1.00 70.60  ? 94  ALA D O   1 
ATOM   1768 C  CB  . ALA B 2 94  ? 85.267  92.839  131.459 1.00 70.60  ? 94  ALA D CB  1 
ATOM   1769 N  N   . LYS B 2 95  ? 85.201  91.202  134.286 1.00 69.99  ? 95  LYS D N   1 
ATOM   1770 C  CA  . LYS B 2 95  ? 85.770  90.908  135.595 1.00 69.99  ? 95  LYS D CA  1 
ATOM   1771 C  C   . LYS B 2 95  ? 87.219  90.472  135.426 1.00 69.99  ? 95  LYS D C   1 
ATOM   1772 O  O   . LYS B 2 95  ? 87.504  89.532  134.677 1.00 69.99  ? 95  LYS D O   1 
ATOM   1773 C  CB  . LYS B 2 95  ? 84.964  89.822  136.307 1.00 69.99  ? 95  LYS D CB  1 
ATOM   1774 C  CG  . LYS B 2 95  ? 83.518  90.201  136.583 1.00 69.99  ? 95  LYS D CG  1 
ATOM   1775 C  CD  . LYS B 2 95  ? 83.434  91.330  137.592 1.00 69.99  ? 95  LYS D CD  1 
ATOM   1776 C  CE  . LYS B 2 95  ? 81.998  91.614  137.995 1.00 69.99  ? 95  LYS D CE  1 
ATOM   1777 N  NZ  . LYS B 2 95  ? 81.924  92.659  139.052 1.00 69.99  ? 95  LYS D NZ  1 
ATOM   1778 N  N   . ILE B 2 96  ? 88.125  91.154  136.120 1.00 74.90  ? 96  ILE D N   1 
ATOM   1779 C  CA  . ILE B 2 96  ? 89.544  90.816  136.130 1.00 74.90  ? 96  ILE D CA  1 
ATOM   1780 C  C   . ILE B 2 96  ? 89.963  90.603  137.577 1.00 74.90  ? 96  ILE D C   1 
ATOM   1781 O  O   . ILE B 2 96  ? 89.767  91.487  138.421 1.00 74.90  ? 96  ILE D O   1 
ATOM   1782 C  CB  . ILE B 2 96  ? 90.400  91.905  135.465 1.00 74.90  ? 96  ILE D CB  1 
ATOM   1783 C  CG1 . ILE B 2 96  ? 90.142  91.944  133.957 1.00 74.90  ? 96  ILE D CG1 1 
ATOM   1784 C  CG2 . ILE B 2 96  ? 91.875  91.669  135.745 1.00 74.90  ? 96  ILE D CG2 1 
ATOM   1785 C  CD1 . ILE B 2 96  ? 89.209  93.051  133.524 1.00 74.90  ? 96  ILE D CD1 1 
ATOM   1786 N  N   . GLU B 2 97  ? 90.536  89.440  137.862 1.00 80.33  ? 97  GLU D N   1 
ATOM   1787 C  CA  . GLU B 2 97  ? 90.986  89.114  139.206 1.00 80.33  ? 97  GLU D CA  1 
ATOM   1788 C  C   . GLU B 2 97  ? 92.478  89.396  139.352 1.00 80.33  ? 97  GLU D C   1 
ATOM   1789 O  O   . GLU B 2 97  ? 93.206  89.547  138.368 1.00 80.33  ? 97  GLU D O   1 
ATOM   1790 C  CB  . GLU B 2 97  ? 90.691  87.649  139.532 1.00 80.33  ? 97  GLU D CB  1 
ATOM   1791 C  CG  . GLU B 2 97  ? 89.251  87.230  139.274 1.00 80.33  ? 97  GLU D CG  1 
ATOM   1792 C  CD  . GLU B 2 97  ? 88.253  87.996  140.122 1.00 80.33  ? 97  GLU D CD  1 
ATOM   1793 O  OE1 . GLU B 2 97  ? 88.603  88.384  141.257 1.00 80.33  ? 97  GLU D OE1 1 
ATOM   1794 O  OE2 . GLU B 2 97  ? 87.115  88.209  139.653 1.00 80.33  ? 97  GLU D OE2 1 
ATOM   1795 N  N   . LEU B 2 98  ? 92.925  89.474  140.605 1.00 76.83  ? 98  LEU D N   1 
ATOM   1796 C  CA  . LEU B 2 98  ? 94.336  89.751  140.862 1.00 76.83  ? 98  LEU D CA  1 
ATOM   1797 C  C   . LEU B 2 98  ? 95.270  88.689  140.289 1.00 76.83  ? 98  LEU D C   1 
ATOM   1798 O  O   . LEU B 2 98  ? 96.257  89.071  139.636 1.00 76.83  ? 98  LEU D O   1 
ATOM   1799 C  CB  . LEU B 2 98  ? 94.566  89.934  142.369 1.00 76.83  ? 98  LEU D CB  1 
ATOM   1800 C  CG  . LEU B 2 98  ? 96.025  89.991  142.829 1.00 76.83  ? 98  LEU D CG  1 
ATOM   1801 C  CD1 . LEU B 2 98  ? 96.727  91.206  142.242 1.00 76.83  ? 98  LEU D CD1 1 
ATOM   1802 C  CD2 . LEU B 2 98  ? 96.110  90.000  144.347 1.00 76.83  ? 98  LEU D CD2 1 
ATOM   1803 N  N   . PRO B 2 99  ? 95.043  87.375  140.476 1.00 72.86  ? 99  PRO D N   1 
ATOM   1804 C  CA  . PRO B 2 99  ? 95.901  86.398  139.793 1.00 72.86  ? 99  PRO D CA  1 
ATOM   1805 C  C   . PRO B 2 99  ? 95.558  86.301  138.317 1.00 72.86  ? 99  PRO D C   1 
ATOM   1806 O  O   . PRO B 2 99  ? 94.525  85.733  137.948 1.00 72.86  ? 99  PRO D O   1 
ATOM   1807 C  CB  . PRO B 2 99  ? 95.610  85.083  140.531 1.00 72.86  ? 99  PRO D CB  1 
ATOM   1808 C  CG  . PRO B 2 99  ? 94.836  85.470  141.760 1.00 72.86  ? 99  PRO D CG  1 
ATOM   1809 C  CD  . PRO B 2 99  ? 94.095  86.704  141.381 1.00 72.86  ? 99  PRO D CD  1 
ATOM   1810 N  N   . ILE B 2 100 ? 96.420  86.852  137.462 1.00 61.31  ? 100 ILE D N   1 
ATOM   1811 C  CA  . ILE B 2 100 ? 96.140  86.882  136.034 1.00 61.31  ? 100 ILE D CA  1 
ATOM   1812 C  C   . ILE B 2 100 ? 96.423  85.517  135.423 1.00 61.31  ? 100 ILE D C   1 
ATOM   1813 O  O   . ILE B 2 100 ? 97.488  84.923  135.641 1.00 61.31  ? 100 ILE D O   1 
ATOM   1814 C  CB  . ILE B 2 100 ? 96.967  87.982  135.348 1.00 61.31  ? 100 ILE D CB  1 
ATOM   1815 C  CG1 . ILE B 2 100 ? 96.760  89.322  136.055 1.00 61.31  ? 100 ILE D CG1 1 
ATOM   1816 C  CG2 . ILE B 2 100 ? 96.586  88.096  133.883 1.00 61.31  ? 100 ILE D CG2 1 
ATOM   1817 C  CD1 . ILE B 2 100 ? 95.406  89.946  135.799 1.00 61.31  ? 100 ILE D CD1 1 
ATOM   1818 N  N   . ARG B 2 101 ? 95.462  85.007  134.656 1.00 70.58  ? 101 ARG D N   1 
ATOM   1819 C  CA  . ARG B 2 101 ? 95.609  83.734  133.969 1.00 70.58  ? 101 ARG D CA  1 
ATOM   1820 C  C   . ARG B 2 101 ? 95.372  83.944  132.480 1.00 70.58  ? 101 ARG D C   1 
ATOM   1821 O  O   . ARG B 2 101 ? 95.122  85.061  132.022 1.00 70.58  ? 101 ARG D O   1 
ATOM   1822 C  CB  . ARG B 2 101 ? 94.644  82.674  134.519 1.00 70.58  ? 101 ARG D CB  1 
ATOM   1823 C  CG  . ARG B 2 101 ? 94.394  82.775  136.015 1.00 70.58  ? 101 ARG D CG  1 
ATOM   1824 C  CD  . ARG B 2 101 ? 94.012  81.426  136.603 1.00 70.58  ? 101 ARG D CD  1 
ATOM   1825 N  NE  . ARG B 2 101 ? 95.142  80.504  136.628 1.00 70.58  ? 101 ARG D NE  1 
ATOM   1826 C  CZ  . ARG B 2 101 ? 95.889  80.265  137.697 1.00 70.58  ? 101 ARG D CZ  1 
ATOM   1827 N  NH1 . ARG B 2 101 ? 95.654  80.863  138.853 1.00 70.58  ? 101 ARG D NH1 1 
ATOM   1828 N  NH2 . ARG B 2 101 ? 96.899  79.405  137.603 1.00 70.58  ? 101 ARG D NH2 1 
ATOM   1829 N  N   . LYS B 2 102 ? 95.458  82.846  131.725 1.00 66.68  ? 102 LYS D N   1 
ATOM   1830 C  CA  . LYS B 2 102 ? 95.304  82.928  130.276 1.00 66.68  ? 102 LYS D CA  1 
ATOM   1831 C  C   . LYS B 2 102 ? 93.899  83.364  129.883 1.00 66.68  ? 102 LYS D C   1 
ATOM   1832 O  O   . LYS B 2 102 ? 93.723  84.135  128.933 1.00 66.68  ? 102 LYS D O   1 
ATOM   1833 C  CB  . LYS B 2 102 ? 95.644  81.583  129.633 1.00 66.68  ? 102 LYS D CB  1 
ATOM   1834 C  CG  . LYS B 2 102 ? 95.627  81.606  128.114 1.00 66.68  ? 102 LYS D CG  1 
ATOM   1835 C  CD  . LYS B 2 102 ? 96.389  80.427  127.535 1.00 66.68  ? 102 LYS D CD  1 
ATOM   1836 C  CE  . LYS B 2 102 ? 95.752  79.107  127.936 1.00 66.68  ? 102 LYS D CE  1 
ATOM   1837 N  NZ  . LYS B 2 102 ? 94.493  78.848  127.186 1.00 66.68  ? 102 LYS D NZ  1 
ATOM   1838 N  N   . ASN B 2 103 ? 92.882  82.875  130.597 1.00 69.44  ? 103 ASN D N   1 
ATOM   1839 C  CA  . ASN B 2 103 ? 91.503  83.191  130.241 1.00 69.44  ? 103 ASN D CA  1 
ATOM   1840 C  C   . ASN B 2 103 ? 91.185  84.673  130.387 1.00 69.44  ? 103 ASN D C   1 
ATOM   1841 O  O   . ASN B 2 103 ? 90.274  85.166  129.713 1.00 69.44  ? 103 ASN D O   1 
ATOM   1842 C  CB  . ASN B 2 103 ? 90.536  82.357  131.085 1.00 69.44  ? 103 ASN D CB  1 
ATOM   1843 C  CG  . ASN B 2 103 ? 90.689  82.607  132.572 1.00 69.44  ? 103 ASN D CG  1 
ATOM   1844 O  OD1 . ASN B 2 103 ? 90.329  83.670  133.077 1.00 69.44  ? 103 ASN D OD1 1 
ATOM   1845 N  ND2 . ASN B 2 103 ? 91.225  81.623  133.283 1.00 69.44  ? 103 ASN D ND2 1 
ATOM   1846 N  N   . HIS B 2 104 ? 91.907  85.392  131.249 1.00 67.04  ? 104 HIS D N   1 
ATOM   1847 C  CA  . HIS B 2 104 ? 91.693  86.831  131.365 1.00 67.04  ? 104 HIS D CA  1 
ATOM   1848 C  C   . HIS B 2 104 ? 92.176  87.563  130.120 1.00 67.04  ? 104 HIS D C   1 
ATOM   1849 O  O   . HIS B 2 104 ? 91.599  88.586  129.731 1.00 67.04  ? 104 HIS D O   1 
ATOM   1850 C  CB  . HIS B 2 104 ? 92.397  87.369  132.610 1.00 67.04  ? 104 HIS D CB  1 
ATOM   1851 C  CG  . HIS B 2 104 ? 91.800  86.890  133.895 1.00 67.04  ? 104 HIS D CG  1 
ATOM   1852 N  ND1 . HIS B 2 104 ? 92.495  86.107  134.792 1.00 67.04  ? 104 HIS D ND1 1 
ATOM   1853 C  CD2 . HIS B 2 104 ? 90.573  87.082  134.435 1.00 67.04  ? 104 HIS D CD2 1 
ATOM   1854 C  CE1 . HIS B 2 104 ? 91.722  85.838  135.829 1.00 67.04  ? 104 HIS D CE1 1 
ATOM   1855 N  NE2 . HIS B 2 104 ? 90.551  86.417  135.637 1.00 67.04  ? 104 HIS D NE2 1 
ATOM   1856 N  N   . ILE B 2 105 ? 93.237  87.059  129.486 1.00 58.70  ? 105 ILE D N   1 
ATOM   1857 C  CA  . ILE B 2 105 ? 93.778  87.712  128.296 1.00 58.70  ? 105 ILE D CA  1 
ATOM   1858 C  C   . ILE B 2 105 ? 92.767  87.667  127.158 1.00 58.70  ? 105 ILE D C   1 
ATOM   1859 O  O   . ILE B 2 105 ? 92.570  88.654  126.440 1.00 58.70  ? 105 ILE D O   1 
ATOM   1860 C  CB  . ILE B 2 105 ? 95.114  87.065  127.889 1.00 58.70  ? 105 ILE D CB  1 
ATOM   1861 C  CG1 . ILE B 2 105 ? 96.083  87.051  129.072 1.00 58.70  ? 105 ILE D CG1 1 
ATOM   1862 C  CG2 . ILE B 2 105 ? 95.722  87.803  126.709 1.00 58.70  ? 105 ILE D CG2 1 
ATOM   1863 C  CD1 . ILE B 2 105 ? 96.259  88.400  129.733 1.00 58.70  ? 105 ILE D CD1 1 
ATOM   1864 N  N   . ASP B 2 106 ? 92.119  86.515  126.968 1.00 64.69  ? 106 ASP D N   1 
ATOM   1865 C  CA  . ASP B 2 106 ? 91.114  86.400  125.916 1.00 64.69  ? 106 ASP D CA  1 
ATOM   1866 C  C   . ASP B 2 106 ? 89.941  87.338  126.169 1.00 64.69  ? 106 ASP D C   1 
ATOM   1867 O  O   . ASP B 2 106 ? 89.444  87.989  125.242 1.00 64.69  ? 106 ASP D O   1 
ATOM   1868 C  CB  . ASP B 2 106 ? 90.634  84.954  125.804 1.00 64.69  ? 106 ASP D CB  1 
ATOM   1869 C  CG  . ASP B 2 106 ? 91.609  84.074  125.049 1.00 64.69  ? 106 ASP D CG  1 
ATOM   1870 O  OD1 . ASP B 2 106 ? 92.407  83.372  125.703 1.00 64.69  ? 106 ASP D OD1 1 
ATOM   1871 O  OD2 . ASP B 2 106 ? 91.577  84.084  123.801 1.00 64.69  ? 106 ASP D OD2 1 
ATOM   1872 N  N   . LEU B 2 107 ? 89.492  87.428  127.423 1.00 61.40  ? 107 LEU D N   1 
ATOM   1873 C  CA  . LEU B 2 107 ? 88.415  88.352  127.761 1.00 61.40  ? 107 LEU D CA  1 
ATOM   1874 C  C   . LEU B 2 107 ? 88.833  89.794  127.501 1.00 61.40  ? 107 LEU D C   1 
ATOM   1875 O  O   . LEU B 2 107 ? 88.052  90.594  126.975 1.00 61.40  ? 107 LEU D O   1 
ATOM   1876 C  CB  . LEU B 2 107 ? 88.005  88.165  129.221 1.00 61.40  ? 107 LEU D CB  1 
ATOM   1877 C  CG  . LEU B 2 107 ? 87.115  89.255  129.822 1.00 61.40  ? 107 LEU D CG  1 
ATOM   1878 C  CD1 . LEU B 2 107 ? 85.776  89.319  129.104 1.00 61.40  ? 107 LEU D CD1 1 
ATOM   1879 C  CD2 . LEU B 2 107 ? 86.920  89.028  131.312 1.00 61.40  ? 107 LEU D CD2 1 
ATOM   1880 N  N   . LEU B 2 108 ? 90.068  90.143  127.871 1.00 61.25  ? 108 LEU D N   1 
ATOM   1881 C  CA  . LEU B 2 108 ? 90.551  91.502  127.655 1.00 61.25  ? 108 LEU D CA  1 
ATOM   1882 C  C   . LEU B 2 108 ? 90.601  91.834  126.169 1.00 61.25  ? 108 LEU D C   1 
ATOM   1883 O  O   . LEU B 2 108 ? 90.206  92.931  125.752 1.00 61.25  ? 108 LEU D O   1 
ATOM   1884 C  CB  . LEU B 2 108 ? 91.930  91.666  128.290 1.00 61.25  ? 108 LEU D CB  1 
ATOM   1885 C  CG  . LEU B 2 108 ? 91.962  92.341  129.661 1.00 61.25  ? 108 LEU D CG  1 
ATOM   1886 C  CD1 . LEU B 2 108 ? 93.366  92.311  130.239 1.00 61.25  ? 108 LEU D CD1 1 
ATOM   1887 C  CD2 . LEU B 2 108 ? 91.441  93.759  129.581 1.00 61.25  ? 108 LEU D CD2 1 
ATOM   1888 N  N   . ILE B 2 109 ? 91.078  90.890  125.356 1.00 59.52  ? 109 ILE D N   1 
ATOM   1889 C  CA  . ILE B 2 109 ? 91.111  91.089  123.910 1.00 59.52  ? 109 ILE D CA  1 
ATOM   1890 C  C   . ILE B 2 109 ? 89.699  91.273  123.372 1.00 59.52  ? 109 ILE D C   1 
ATOM   1891 O  O   . ILE B 2 109 ? 89.443  92.146  122.534 1.00 59.52  ? 109 ILE D O   1 
ATOM   1892 C  CB  . ILE B 2 109 ? 91.828  89.911  123.226 1.00 59.52  ? 109 ILE D CB  1 
ATOM   1893 C  CG1 . ILE B 2 109 ? 93.335  89.984  123.475 1.00 59.52  ? 109 ILE D CG1 1 
ATOM   1894 C  CG2 . ILE B 2 109 ? 91.538  89.896  121.739 1.00 59.52  ? 109 ILE D CG2 1 
ATOM   1895 C  CD1 . ILE B 2 109 ? 94.086  88.757  123.012 1.00 59.52  ? 109 ILE D CD1 1 
ATOM   1896 N  N   . ASP B 2 110 ? 88.758  90.455  123.853 1.00 72.11  ? 110 ASP D N   1 
ATOM   1897 C  CA  . ASP B 2 110 ? 87.379  90.554  123.384 1.00 72.11  ? 110 ASP D CA  1 
ATOM   1898 C  C   . ASP B 2 110 ? 86.768  91.906  123.730 1.00 72.11  ? 110 ASP D C   1 
ATOM   1899 O  O   . ASP B 2 110 ? 86.050  92.497  122.915 1.00 72.11  ? 110 ASP D O   1 
ATOM   1900 C  CB  . ASP B 2 110 ? 86.544  89.420  123.976 1.00 72.11  ? 110 ASP D CB  1 
ATOM   1901 C  CG  . ASP B 2 110 ? 85.216  89.245  123.268 1.00 72.11  ? 110 ASP D CG  1 
ATOM   1902 O  OD1 . ASP B 2 110 ? 85.139  89.569  122.064 1.00 72.11  ? 110 ASP D OD1 1 
ATOM   1903 O  OD2 . ASP B 2 110 ? 84.252  88.783  123.913 1.00 72.11  ? 110 ASP D OD2 1 
ATOM   1904 N  N   . VAL B 2 111 ? 87.032  92.409  124.938 1.00 64.78  ? 111 VAL D N   1 
ATOM   1905 C  CA  . VAL B 2 111 ? 86.522  93.725  125.317 1.00 64.78  ? 111 VAL D CA  1 
ATOM   1906 C  C   . VAL B 2 111 ? 87.147  94.813  124.452 1.00 64.78  ? 111 VAL D C   1 
ATOM   1907 O  O   . VAL B 2 111 ? 86.453  95.717  123.972 1.00 64.78  ? 111 VAL D O   1 
ATOM   1908 C  CB  . VAL B 2 111 ? 86.754  93.994  126.814 1.00 64.78  ? 111 VAL D CB  1 
ATOM   1909 C  CG1 . VAL B 2 111 ? 86.104  95.305  127.209 1.00 64.78  ? 111 VAL D CG1 1 
ATOM   1910 C  CG2 . VAL B 2 111 ? 86.163  92.877  127.645 1.00 64.78  ? 111 VAL D CG2 1 
ATOM   1911 N  N   . PHE B 2 112 ? 88.463  94.748  124.239 1.00 64.14  ? 112 PHE D N   1 
ATOM   1912 C  CA  . PHE B 2 112 ? 89.126  95.787  123.458 1.00 64.14  ? 112 PHE D CA  1 
ATOM   1913 C  C   . PHE B 2 112 ? 88.936  95.622  121.956 1.00 64.14  ? 112 PHE D C   1 
ATOM   1914 O  O   . PHE B 2 112 ? 89.243  96.554  121.205 1.00 64.14  ? 112 PHE D O   1 
ATOM   1915 C  CB  . PHE B 2 112 ? 90.621  95.827  123.775 1.00 64.14  ? 112 PHE D CB  1 
ATOM   1916 C  CG  . PHE B 2 112 ? 90.931  96.194  125.196 1.00 64.14  ? 112 PHE D CG  1 
ATOM   1917 C  CD1 . PHE B 2 112 ? 90.122  97.078  125.888 1.00 64.14  ? 112 PHE D CD1 1 
ATOM   1918 C  CD2 . PHE B 2 112 ? 92.043  95.674  125.832 1.00 64.14  ? 112 PHE D CD2 1 
ATOM   1919 C  CE1 . PHE B 2 112 ? 90.409  97.424  127.193 1.00 64.14  ? 112 PHE D CE1 1 
ATOM   1920 C  CE2 . PHE B 2 112 ? 92.336  96.018  127.134 1.00 64.14  ? 112 PHE D CE2 1 
ATOM   1921 C  CZ  . PHE B 2 112 ? 91.518  96.893  127.817 1.00 64.14  ? 112 PHE D CZ  1 
ATOM   1922 N  N   . ARG B 2 113 ? 88.448  94.466  121.500 1.00 82.42  ? 113 ARG D N   1 
ATOM   1923 C  CA  . ARG B 2 113 ? 88.299  94.245  120.065 1.00 82.42  ? 113 ARG D CA  1 
ATOM   1924 C  C   . ARG B 2 113 ? 87.262  95.175  119.447 1.00 82.42  ? 113 ARG D C   1 
ATOM   1925 O  O   . ARG B 2 113 ? 87.478  95.700  118.349 1.00 82.42  ? 113 ARG D O   1 
ATOM   1926 C  CB  . ARG B 2 113 ? 87.930  92.788  119.792 1.00 82.42  ? 113 ARG D CB  1 
ATOM   1927 C  CG  . ARG B 2 113 ? 88.573  92.217  118.542 1.00 82.42  ? 113 ARG D CG  1 
ATOM   1928 C  CD  . ARG B 2 113 ? 88.124  90.789  118.290 1.00 82.42  ? 113 ARG D CD  1 
ATOM   1929 N  NE  . ARG B 2 113 ? 89.056  89.813  118.843 1.00 82.42  ? 113 ARG D NE  1 
ATOM   1930 C  CZ  . ARG B 2 113 ? 90.155  89.398  118.230 1.00 82.42  ? 113 ARG D CZ  1 
ATOM   1931 N  NH1 . ARG B 2 113 ? 90.510  89.877  117.051 1.00 82.42  ? 113 ARG D NH1 1 
ATOM   1932 N  NH2 . ARG B 2 113 ? 90.918  88.479  118.815 1.00 82.42  ? 113 ARG D NH2 1 
ATOM   1933 N  N   . LYS B 2 114 ? 86.137  95.386  120.125 1.00 94.30  ? 114 LYS D N   1 
ATOM   1934 C  CA  . LYS B 2 114 ? 85.066  96.212  119.584 1.00 94.30  ? 114 LYS D CA  1 
ATOM   1935 C  C   . LYS B 2 114 ? 85.498  97.669  119.488 1.00 94.30  ? 114 LYS D C   1 
ATOM   1936 O  O   . LYS B 2 114 ? 86.244  98.169  120.334 1.00 94.30  ? 114 LYS D O   1 
ATOM   1937 C  CB  . LYS B 2 114 ? 83.813  96.098  120.453 1.00 94.30  ? 114 LYS D CB  1 
ATOM   1938 C  CG  . LYS B 2 114 ? 83.217  94.702  120.505 1.00 94.30  ? 114 LYS D CG  1 
ATOM   1939 C  CD  . LYS B 2 114 ? 81.969  94.670  121.371 1.00 94.30  ? 114 LYS D CD  1 
ATOM   1940 C  CE  . LYS B 2 114 ? 81.424  93.258  121.505 1.00 94.30  ? 114 LYS D CE  1 
ATOM   1941 N  NZ  . LYS B 2 114 ? 80.225  93.210  122.386 1.00 94.30  ? 114 LYS D NZ  1 
ATOM   1942 N  N   . LYS B 2 115 ? 85.022  98.350  118.443 1.00 107.68 ? 115 LYS D N   1 
ATOM   1943 C  CA  . LYS B 2 115 ? 85.346  99.759  118.260 1.00 107.68 ? 115 LYS D CA  1 
ATOM   1944 C  C   . LYS B 2 115 ? 84.580  100.660 119.220 1.00 107.68 ? 115 LYS D C   1 
ATOM   1945 O  O   . LYS B 2 115 ? 84.987  101.807 119.430 1.00 107.68 ? 115 LYS D O   1 
ATOM   1946 C  CB  . LYS B 2 115 ? 85.067  100.179 116.815 1.00 107.68 ? 115 LYS D CB  1 
ATOM   1947 C  CG  . LYS B 2 115 ? 83.592  100.218 116.453 1.00 107.68 ? 115 LYS D CG  1 
ATOM   1948 C  CD  . LYS B 2 115 ? 83.389  100.598 114.995 1.00 107.68 ? 115 LYS D CD  1 
ATOM   1949 C  CE  . LYS B 2 115 ? 83.876  102.012 114.720 1.00 107.68 ? 115 LYS D CE  1 
ATOM   1950 N  NZ  . LYS B 2 115 ? 83.643  102.414 113.305 1.00 107.68 ? 115 LYS D NZ  1 
ATOM   1951 N  N   . ARG B 2 116 ? 83.489  100.170 119.803 1.00 105.21 ? 116 ARG D N   1 
ATOM   1952 C  CA  . ARG B 2 116 ? 82.700  100.939 120.752 1.00 105.21 ? 116 ARG D CA  1 
ATOM   1953 C  C   . ARG B 2 116 ? 82.344  100.051 121.934 1.00 105.21 ? 116 ARG D C   1 
ATOM   1954 O  O   . ARG B 2 116 ? 82.320  98.822  121.829 1.00 105.21 ? 116 ARG D O   1 
ATOM   1955 C  CB  . ARG B 2 116 ? 81.427  101.506 120.108 1.00 105.21 ? 116 ARG D CB  1 
ATOM   1956 C  CG  . ARG B 2 116 ? 81.675  102.675 119.168 1.00 105.21 ? 116 ARG D CG  1 
ATOM   1957 C  CD  . ARG B 2 116 ? 80.397  103.098 118.462 1.00 105.21 ? 116 ARG D CD  1 
ATOM   1958 N  NE  . ARG B 2 116 ? 79.885  102.053 117.584 1.00 105.21 ? 116 ARG D NE  1 
ATOM   1959 C  CZ  . ARG B 2 116 ? 78.956  102.243 116.656 1.00 105.21 ? 116 ARG D CZ  1 
ATOM   1960 N  NH1 . ARG B 2 116 ? 78.411  103.431 116.457 1.00 105.21 ? 116 ARG D NH1 1 
ATOM   1961 N  NH2 . ARG B 2 116 ? 78.566  101.214 115.910 1.00 105.21 ? 116 ARG D NH2 1 
ATOM   1962 N  N   . GLY B 2 117 ? 82.060  100.690 123.066 1.00 91.93  ? 117 GLY D N   1 
ATOM   1963 C  CA  . GLY B 2 117 ? 81.756  99.960  124.280 1.00 91.93  ? 117 GLY D CA  1 
ATOM   1964 C  C   . GLY B 2 117 ? 82.931  99.148  124.784 1.00 91.93  ? 117 GLY D C   1 
ATOM   1965 O  O   . GLY B 2 117 ? 82.783  97.968  125.115 1.00 91.93  ? 117 GLY D O   1 
ATOM   1966 N  N   . ASN B 2 118 ? 84.112  99.767  124.829 1.00 87.71  ? 118 ASN D N   1 
ATOM   1967 C  CA  . ASN B 2 118 ? 85.323  99.096  125.282 1.00 87.71  ? 118 ASN D CA  1 
ATOM   1968 C  C   . ASN B 2 118 ? 85.956  99.769  126.494 1.00 87.71  ? 118 ASN D C   1 
ATOM   1969 O  O   . ASN B 2 118 ? 87.183  99.734  126.635 1.00 87.71  ? 118 ASN D O   1 
ATOM   1970 C  CB  . ASN B 2 118 ? 86.349  99.010  124.143 1.00 87.71  ? 118 ASN D CB  1 
ATOM   1971 C  CG  . ASN B 2 118 ? 86.632  100.360 123.503 1.00 87.71  ? 118 ASN D CG  1 
ATOM   1972 O  OD1 . ASN B 2 118 ? 86.406  101.409 124.104 1.00 87.71  ? 118 ASN D OD1 1 
ATOM   1973 N  ND2 . ASN B 2 118 ? 87.136  100.334 122.275 1.00 87.71  ? 118 ASN D ND2 1 
ATOM   1974 N  N   . ARG B 2 119 ? 85.161  100.384 127.366 1.00 80.46  ? 119 ARG D N   1 
ATOM   1975 C  CA  . ARG B 2 119 ? 85.709  101.079 128.524 1.00 80.46  ? 119 ARG D CA  1 
ATOM   1976 C  C   . ARG B 2 119 ? 85.613  100.193 129.760 1.00 80.46  ? 119 ARG D C   1 
ATOM   1977 O  O   . ARG B 2 119 ? 84.515  99.801  130.169 1.00 80.46  ? 119 ARG D O   1 
ATOM   1978 C  CB  . ARG B 2 119 ? 84.969  102.395 128.743 1.00 80.46  ? 119 ARG D CB  1 
ATOM   1979 C  CG  . ARG B 2 119 ? 85.239  103.436 127.670 1.00 80.46  ? 119 ARG D CG  1 
ATOM   1980 C  CD  . ARG B 2 119 ? 84.196  104.540 127.695 1.00 80.46  ? 119 ARG D CD  1 
ATOM   1981 N  NE  . ARG B 2 119 ? 84.315  105.383 128.878 1.00 80.46  ? 119 ARG D NE  1 
ATOM   1982 C  CZ  . ARG B 2 119 ? 83.286  105.816 129.593 1.00 80.46  ? 119 ARG D CZ  1 
ATOM   1983 N  NH1 . ARG B 2 119 ? 82.042  105.495 129.279 1.00 80.46  ? 119 ARG D NH1 1 
ATOM   1984 N  NH2 . ARG B 2 119 ? 83.511  106.592 130.648 1.00 80.46  ? 119 ARG D NH2 1 
ATOM   1985 N  N   . LEU B 2 120 ? 86.761  99.880  130.354 1.00 62.04  ? 120 LEU D N   1 
ATOM   1986 C  CA  . LEU B 2 120 ? 86.787  99.062  131.555 1.00 62.04  ? 120 LEU D CA  1 
ATOM   1987 C  C   . LEU B 2 120 ? 86.501  99.907  132.793 1.00 62.04  ? 120 LEU D C   1 
ATOM   1988 O  O   . LEU B 2 120 ? 86.556  101.140 132.767 1.00 62.04  ? 120 LEU D O   1 
ATOM   1989 C  CB  . LEU B 2 120 ? 88.141  98.370  131.707 1.00 62.04  ? 120 LEU D CB  1 
ATOM   1990 C  CG  . LEU B 2 120 ? 88.427  97.195  130.777 1.00 62.04  ? 120 LEU D CG  1 
ATOM   1991 C  CD1 . LEU B 2 120 ? 89.819  96.655  131.038 1.00 62.04  ? 120 LEU D CD1 1 
ATOM   1992 C  CD2 . LEU B 2 120 ? 87.385  96.107  130.958 1.00 62.04  ? 120 LEU D CD2 1 
ATOM   1993 N  N   . HIS B 2 121 ? 86.188  99.223  133.887 1.00 64.19  ? 121 HIS D N   1 
ATOM   1994 C  CA  . HIS B 2 121 ? 85.975  99.909  135.151 1.00 64.19  ? 121 HIS D CA  1 
ATOM   1995 C  C   . HIS B 2 121 ? 87.307  100.435 135.685 1.00 64.19  ? 121 HIS D C   1 
ATOM   1996 O  O   . HIS B 2 121 ? 88.327  99.746  135.592 1.00 64.19  ? 121 HIS D O   1 
ATOM   1997 C  CB  . HIS B 2 121 ? 85.328  98.970  136.168 1.00 64.19  ? 121 HIS D CB  1 
ATOM   1998 C  CG  . HIS B 2 121 ? 84.674  99.675  137.315 1.00 64.19  ? 121 HIS D CG  1 
ATOM   1999 N  ND1 . HIS B 2 121 ? 85.380  100.144 138.401 1.00 64.19  ? 121 HIS D ND1 1 
ATOM   2000 C  CD2 . HIS B 2 121 ? 83.378  99.994  137.543 1.00 64.19  ? 121 HIS D CD2 1 
ATOM   2001 C  CE1 . HIS B 2 121 ? 84.548  100.720 139.250 1.00 64.19  ? 121 HIS D CE1 1 
ATOM   2002 N  NE2 . HIS B 2 121 ? 83.327  100.642 138.752 1.00 64.19  ? 121 HIS D NE2 1 
ATOM   2003 N  N   . PRO B 2 122 ? 87.331  101.648 136.241 1.00 54.57  ? 122 PRO D N   1 
ATOM   2004 C  CA  . PRO B 2 122 ? 88.606  102.217 136.709 1.00 54.57  ? 122 PRO D CA  1 
ATOM   2005 C  C   . PRO B 2 122 ? 89.304  101.379 137.764 1.00 54.57  ? 122 PRO D C   1 
ATOM   2006 O  O   . PRO B 2 122 ? 90.538  101.426 137.865 1.00 54.57  ? 122 PRO D O   1 
ATOM   2007 C  CB  . PRO B 2 122 ? 88.188  103.585 137.264 1.00 54.57  ? 122 PRO D CB  1 
ATOM   2008 C  CG  . PRO B 2 122 ? 86.930  103.918 136.540 1.00 54.57  ? 122 PRO D CG  1 
ATOM   2009 C  CD  . PRO B 2 122 ? 86.223  102.613 136.332 1.00 54.57  ? 122 PRO D CD  1 
ATOM   2010 N  N   . LYS B 2 123 ? 88.552  100.610 138.554 1.00 49.29  ? 123 LYS D N   1 
ATOM   2011 C  CA  . LYS B 2 123 ? 89.169  99.773  139.577 1.00 49.29  ? 123 LYS D CA  1 
ATOM   2012 C  C   . LYS B 2 123 ? 90.114  98.750  138.961 1.00 49.29  ? 123 LYS D C   1 
ATOM   2013 O  O   . LYS B 2 123 ? 91.224  98.539  139.462 1.00 49.29  ? 123 LYS D O   1 
ATOM   2014 C  CB  . LYS B 2 123 ? 88.088  99.071  140.397 1.00 49.29  ? 123 LYS D CB  1 
ATOM   2015 C  CG  . LYS B 2 123 ? 88.627  98.114  141.446 1.00 49.29  ? 123 LYS D CG  1 
ATOM   2016 C  CD  . LYS B 2 123 ? 87.519  97.633  142.364 1.00 49.29  ? 123 LYS D CD  1 
ATOM   2017 C  CE  . LYS B 2 123 ? 86.391  96.998  141.568 1.00 49.29  ? 123 LYS D CE  1 
ATOM   2018 N  NZ  . LYS B 2 123 ? 86.766  95.651  141.058 1.00 49.29  ? 123 LYS D NZ  1 
ATOM   2019 N  N   . TYR B 2 124 ? 89.697  98.111  137.867 1.00 58.69  ? 124 TYR D N   1 
ATOM   2020 C  CA  . TYR B 2 124 ? 90.536  97.099  137.235 1.00 58.69  ? 124 TYR D CA  1 
ATOM   2021 C  C   . TYR B 2 124 ? 91.767  97.716  136.582 1.00 58.69  ? 124 TYR D C   1 
ATOM   2022 O  O   . TYR B 2 124 ? 92.855  97.131  136.631 1.00 58.69  ? 124 TYR D O   1 
ATOM   2023 C  CB  . TYR B 2 124 ? 89.717  96.308  136.218 1.00 58.69  ? 124 TYR D CB  1 
ATOM   2024 C  CG  . TYR B 2 124 ? 88.547  95.591  136.847 1.00 58.69  ? 124 TYR D CG  1 
ATOM   2025 C  CD1 . TYR B 2 124 ? 88.748  94.564  137.758 1.00 58.69  ? 124 TYR D CD1 1 
ATOM   2026 C  CD2 . TYR B 2 124 ? 87.242  95.954  136.546 1.00 58.69  ? 124 TYR D CD2 1 
ATOM   2027 C  CE1 . TYR B 2 124 ? 87.684  93.911  138.343 1.00 58.69  ? 124 TYR D CE1 1 
ATOM   2028 C  CE2 . TYR B 2 124 ? 86.171  95.306  137.127 1.00 58.69  ? 124 TYR D CE2 1 
ATOM   2029 C  CZ  . TYR B 2 124 ? 86.398  94.286  138.024 1.00 58.69  ? 124 TYR D CZ  1 
ATOM   2030 O  OH  . TYR B 2 124 ? 85.335  93.637  138.606 1.00 58.69  ? 124 TYR D OH  1 
ATOM   2031 N  N   . VAL B 2 125 ? 91.618  98.893  135.970 1.00 46.81  ? 125 VAL D N   1 
ATOM   2032 C  CA  . VAL B 2 125 ? 92.770  99.585  135.398 1.00 46.81  ? 125 VAL D CA  1 
ATOM   2033 C  C   . VAL B 2 125 ? 93.775  99.924  136.490 1.00 46.81  ? 125 VAL D C   1 
ATOM   2034 O  O   . VAL B 2 125 ? 94.986  99.716  136.335 1.00 46.81  ? 125 VAL D O   1 
ATOM   2035 C  CB  . VAL B 2 125 ? 92.317  100.845 134.640 1.00 46.81  ? 125 VAL D CB  1 
ATOM   2036 C  CG1 . VAL B 2 125 ? 93.516  101.576 134.066 1.00 46.81  ? 125 VAL D CG1 1 
ATOM   2037 C  CG2 . VAL B 2 125 ? 91.338  100.477 133.541 1.00 46.81  ? 125 VAL D CG2 1 
ATOM   2038 N  N   . ALA B 2 126 ? 93.283  100.447 137.616 1.00 48.11  ? 126 ALA D N   1 
ATOM   2039 C  CA  . ALA B 2 126 ? 94.170  100.769 138.727 1.00 48.11  ? 126 ALA D CA  1 
ATOM   2040 C  C   . ALA B 2 126 ? 94.855  99.520  139.264 1.00 48.11  ? 126 ALA D C   1 
ATOM   2041 O  O   . ALA B 2 126 ? 96.051  99.545  139.570 1.00 48.11  ? 126 ALA D O   1 
ATOM   2042 C  CB  . ALA B 2 126 ? 93.390  101.476 139.835 1.00 48.11  ? 126 ALA D CB  1 
ATOM   2043 N  N   . LEU B 2 127 ? 94.112  98.417  139.382 1.00 49.75  ? 127 LEU D N   1 
ATOM   2044 C  CA  . LEU B 2 127 ? 94.699  97.170  139.865 1.00 49.75  ? 127 LEU D CA  1 
ATOM   2045 C  C   . LEU B 2 127 ? 95.807  96.688  138.939 1.00 49.75  ? 127 LEU D C   1 
ATOM   2046 O  O   . LEU B 2 127 ? 96.894  96.310  139.394 1.00 49.75  ? 127 LEU D O   1 
ATOM   2047 C  CB  . LEU B 2 127 ? 93.613  96.103  140.001 1.00 49.75  ? 127 LEU D CB  1 
ATOM   2048 C  CG  . LEU B 2 127 ? 94.091  94.652  140.091 1.00 49.75  ? 127 LEU D CG  1 
ATOM   2049 C  CD1 . LEU B 2 127 ? 94.854  94.410  141.384 1.00 49.75  ? 127 LEU D CD1 1 
ATOM   2050 C  CD2 . LEU B 2 127 ? 92.919  93.694  139.966 1.00 49.75  ? 127 LEU D CD2 1 
ATOM   2051 N  N   . ILE B 2 128 ? 95.549  96.698  137.629 1.00 43.35  ? 128 ILE D N   1 
ATOM   2052 C  CA  . ILE B 2 128 ? 96.541  96.223  136.668 1.00 43.35  ? 128 ILE D CA  1 
ATOM   2053 C  C   . ILE B 2 128 ? 97.790  97.092  136.723 1.00 43.35  ? 128 ILE D C   1 
ATOM   2054 O  O   . ILE B 2 128 ? 98.918  96.586  136.778 1.00 43.35  ? 128 ILE D O   1 
ATOM   2055 C  CB  . ILE B 2 128 ? 95.942  96.185  135.251 1.00 43.35  ? 128 ILE D CB  1 
ATOM   2056 C  CG1 . ILE B 2 128 ? 94.920  95.055  135.133 1.00 43.35  ? 128 ILE D CG1 1 
ATOM   2057 C  CG2 . ILE B 2 128 ? 97.037  96.014  134.214 1.00 43.35  ? 128 ILE D CG2 1 
ATOM   2058 C  CD1 . ILE B 2 128 ? 95.490  93.688  135.425 1.00 43.35  ? 128 ILE D CD1 1 
ATOM   2059 N  N   . LEU B 2 129 ? 97.607  98.416  136.724 1.00 42.74  ? 129 LEU D N   1 
ATOM   2060 C  CA  . LEU B 2 129 ? 98.758  99.314  136.742 1.00 42.74  ? 129 LEU D CA  1 
ATOM   2061 C  C   . LEU B 2 129 ? 99.557  99.164  138.031 1.00 42.74  ? 129 LEU D C   1 
ATOM   2062 O  O   . LEU B 2 129 ? 100.792 99.130  138.005 1.00 42.74  ? 129 LEU D O   1 
ATOM   2063 C  CB  . LEU B 2 129 ? 98.300  100.760 136.551 1.00 42.74  ? 129 LEU D CB  1 
ATOM   2064 C  CG  . LEU B 2 129 ? 97.712  101.080 135.176 1.00 42.74  ? 129 LEU D CG  1 
ATOM   2065 C  CD1 . LEU B 2 129 ? 97.218  102.514 135.122 1.00 42.74  ? 129 LEU D CD1 1 
ATOM   2066 C  CD2 . LEU B 2 129 ? 98.736  100.823 134.085 1.00 42.74  ? 129 LEU D CD2 1 
ATOM   2067 N  N   . ARG B 2 130 ? 98.868  99.063  139.172 1.00 58.19  ? 130 ARG D N   1 
ATOM   2068 C  CA  . ARG B 2 130 ? 99.561  98.934  140.449 1.00 58.19  ? 130 ARG D CA  1 
ATOM   2069 C  C   . ARG B 2 130 ? 100.340 97.628  140.527 1.00 58.19  ? 130 ARG D C   1 
ATOM   2070 O  O   . ARG B 2 130 ? 101.496 97.613  140.968 1.00 58.19  ? 130 ARG D O   1 
ATOM   2071 C  CB  . ARG B 2 130 ? 98.555  99.028  141.594 1.00 58.19  ? 130 ARG D CB  1 
ATOM   2072 C  CG  . ARG B 2 130 ? 99.129  99.558  142.894 1.00 58.19  ? 130 ARG D CG  1 
ATOM   2073 C  CD  . ARG B 2 130 ? 98.172  99.318  144.049 1.00 58.19  ? 130 ARG D CD  1 
ATOM   2074 N  NE  . ARG B 2 130 ? 96.806  99.700  143.710 1.00 58.19  ? 130 ARG D NE  1 
ATOM   2075 C  CZ  . ARG B 2 130 ? 96.214  100.814 144.119 1.00 58.19  ? 130 ARG D CZ  1 
ATOM   2076 N  NH1 . ARG B 2 130 ? 96.845  101.692 144.880 1.00 58.19  ? 130 ARG D NH1 1 
ATOM   2077 N  NH2 . ARG B 2 130 ? 94.958  101.053 143.754 1.00 58.19  ? 130 ARG D NH2 1 
ATOM   2078 N  N   . GLU B 2 131 ? 99.728  96.520  140.101 1.00 53.33  ? 131 GLU D N   1 
ATOM   2079 C  CA  . GLU B 2 131 ? 100.425 95.240  140.138 1.00 53.33  ? 131 GLU D CA  1 
ATOM   2080 C  C   . GLU B 2 131 ? 101.619 95.234  139.192 1.00 53.33  ? 131 GLU D C   1 
ATOM   2081 O  O   . GLU B 2 131 ? 102.688 94.714  139.536 1.00 53.33  ? 131 GLU D O   1 
ATOM   2082 C  CB  . GLU B 2 131 ? 99.458  94.106  139.801 1.00 53.33  ? 131 GLU D CB  1 
ATOM   2083 C  CG  . GLU B 2 131 ? 100.113 92.741  139.694 1.00 53.33  ? 131 GLU D CG  1 
ATOM   2084 C  CD  . GLU B 2 131 ? 100.151 92.003  141.019 1.00 53.33  ? 131 GLU D CD  1 
ATOM   2085 O  OE1 . GLU B 2 131 ? 100.190 92.669  142.075 1.00 53.33  ? 131 GLU D OE1 1 
ATOM   2086 O  OE2 . GLU B 2 131 ? 100.140 90.754  141.005 1.00 53.33  ? 131 GLU D OE2 1 
ATOM   2087 N  N   . ALA B 2 132 ? 101.462 95.813  137.996 1.00 44.04  ? 132 ALA D N   1 
ATOM   2088 C  CA  . ALA B 2 132 ? 102.576 95.872  137.056 1.00 44.04  ? 132 ALA D CA  1 
ATOM   2089 C  C   . ALA B 2 132 ? 103.716 96.723  137.600 1.00 44.04  ? 132 ALA D C   1 
ATOM   2090 O  O   . ALA B 2 132 ? 104.890 96.368  137.450 1.00 44.04  ? 132 ALA D O   1 
ATOM   2091 C  CB  . ALA B 2 132 ? 102.097 96.411  135.709 1.00 44.04  ? 132 ALA D CB  1 
ATOM   2092 N  N   . ALA B 2 133 ? 103.391 97.854  138.231 1.00 43.80  ? 133 ALA D N   1 
ATOM   2093 C  CA  . ALA B 2 133 ? 104.426 98.697  138.819 1.00 43.80  ? 133 ALA D CA  1 
ATOM   2094 C  C   . ALA B 2 133 ? 105.141 97.974  139.953 1.00 43.80  ? 133 ALA D C   1 
ATOM   2095 O  O   . ALA B 2 133 ? 106.366 98.069  140.092 1.00 43.80  ? 133 ALA D O   1 
ATOM   2096 C  CB  . ALA B 2 133 ? 103.817 100.009 139.312 1.00 43.80  ? 133 ALA D CB  1 
ATOM   2097 N  N   . LYS B 2 134 ? 104.388 97.247  140.782 1.00 52.05  ? 134 LYS D N   1 
ATOM   2098 C  CA  . LYS B 2 134 ? 105.000 96.511  141.884 1.00 52.05  ? 134 LYS D CA  1 
ATOM   2099 C  C   . LYS B 2 134 ? 105.914 95.404  141.374 1.00 52.05  ? 134 LYS D C   1 
ATOM   2100 O  O   . LYS B 2 134 ? 106.986 95.164  141.941 1.00 52.05  ? 134 LYS D O   1 
ATOM   2101 C  CB  . LYS B 2 134 ? 103.918 95.934  142.795 1.00 52.05  ? 134 LYS D CB  1 
ATOM   2102 C  CG  . LYS B 2 134 ? 104.455 95.257  144.044 1.00 52.05  ? 134 LYS D CG  1 
ATOM   2103 C  CD  . LYS B 2 134 ? 103.461 94.249  144.598 1.00 52.05  ? 134 LYS D CD  1 
ATOM   2104 C  CE  . LYS B 2 134 ? 102.160 94.919  145.006 1.00 52.05  ? 134 LYS D CE  1 
ATOM   2105 N  NZ  . LYS B 2 134 ? 101.059 93.932  145.184 1.00 52.05  ? 134 LYS D NZ  1 
ATOM   2106 N  N   . SER B 2 135 ? 105.507 94.714  140.307 1.00 42.49  ? 135 SER D N   1 
ATOM   2107 C  CA  . SER B 2 135 ? 106.286 93.584  139.812 1.00 42.49  ? 135 SER D CA  1 
ATOM   2108 C  C   . SER B 2 135 ? 107.540 94.037  139.071 1.00 42.49  ? 135 SER D C   1 
ATOM   2109 O  O   . SER B 2 135 ? 108.565 93.348  139.096 1.00 42.49  ? 135 SER D O   1 
ATOM   2110 C  CB  . SER B 2 135 ? 105.421 92.708  138.905 1.00 42.49  ? 135 SER D CB  1 
ATOM   2111 O  OG  . SER B 2 135 ? 106.147 91.582  138.447 1.00 42.49  ? 135 SER D OG  1 
ATOM   2112 N  N   . LEU B 2 136 ? 107.478 95.192  138.402 1.00 36.18  ? 136 LEU D N   1 
ATOM   2113 C  CA  . LEU B 2 136 ? 108.593 95.617  137.560 1.00 36.18  ? 136 LEU D CA  1 
ATOM   2114 C  C   . LEU B 2 136 ? 109.767 96.135  138.379 1.00 36.18  ? 136 LEU D C   1 
ATOM   2115 O  O   . LEU B 2 136 ? 110.862 96.324  137.838 1.00 36.18  ? 136 LEU D O   1 
ATOM   2116 C  CB  . LEU B 2 136 ? 108.129 96.690  136.574 1.00 36.18  ? 136 LEU D CB  1 
ATOM   2117 C  CG  . LEU B 2 136 ? 107.417 96.202  135.312 1.00 36.18  ? 136 LEU D CG  1 
ATOM   2118 C  CD1 . LEU B 2 136 ? 106.664 97.340  134.646 1.00 36.18  ? 136 LEU D CD1 1 
ATOM   2119 C  CD2 . LEU B 2 136 ? 108.413 95.584  134.350 1.00 36.18  ? 136 LEU D CD2 1 
ATOM   2120 N  N   . LYS B 2 137 ? 109.566 96.373  139.677 1.00 39.05  ? 137 LYS D N   1 
ATOM   2121 C  CA  . LYS B 2 137 ? 110.628 96.948  140.496 1.00 39.05  ? 137 LYS D CA  1 
ATOM   2122 C  C   . LYS B 2 137 ? 111.782 95.976  140.703 1.00 39.05  ? 137 LYS D C   1 
ATOM   2123 O  O   . LYS B 2 137 ? 112.940 96.398  140.798 1.00 39.05  ? 137 LYS D O   1 
ATOM   2124 C  CB  . LYS B 2 137 ? 110.064 97.394  141.845 1.00 39.05  ? 137 LYS D CB  1 
ATOM   2125 C  CG  . LYS B 2 137 ? 111.025 98.224  142.679 1.00 39.05  ? 137 LYS D CG  1 
ATOM   2126 C  CD  . LYS B 2 137 ? 110.404 98.625  144.007 1.00 39.05  ? 137 LYS D CD  1 
ATOM   2127 C  CE  . LYS B 2 137 ? 109.161 99.473  143.800 1.00 39.05  ? 137 LYS D CE  1 
ATOM   2128 N  NZ  . LYS B 2 137 ? 108.576 99.929  145.090 1.00 39.05  ? 137 LYS D NZ  1 
ATOM   2129 N  N   . GLN B 2 138 ? 111.493 94.677  140.775 1.00 45.98  ? 138 GLN D N   1 
ATOM   2130 C  CA  . GLN B 2 138 ? 112.525 93.692  141.075 1.00 45.98  ? 138 GLN D CA  1 
ATOM   2131 C  C   . GLN B 2 138 ? 113.462 93.428  139.903 1.00 45.98  ? 138 GLN D C   1 
ATOM   2132 O  O   . GLN B 2 138 ? 114.571 92.929  140.119 1.00 45.98  ? 138 GLN D O   1 
ATOM   2133 C  CB  . GLN B 2 138 ? 111.880 92.376  141.514 1.00 45.98  ? 138 GLN D CB  1 
ATOM   2134 C  CG  . GLN B 2 138 ? 110.760 92.538  142.527 1.00 45.98  ? 138 GLN D CG  1 
ATOM   2135 C  CD  . GLN B 2 138 ? 111.214 93.223  143.800 1.00 45.98  ? 138 GLN D CD  1 
ATOM   2136 O  OE1 . GLN B 2 138 ? 112.345 93.041  144.248 1.00 45.98  ? 138 GLN D OE1 1 
ATOM   2137 N  NE2 . GLN B 2 138 ? 110.329 94.016  144.391 1.00 45.98  ? 138 GLN D NE2 1 
ATOM   2138 N  N   . LEU B 2 139 ? 113.048 93.744  138.678 1.00 43.51  ? 139 LEU D N   1 
ATOM   2139 C  CA  . LEU B 2 139 ? 113.846 93.406  137.511 1.00 43.51  ? 139 LEU D CA  1 
ATOM   2140 C  C   . LEU B 2 139 ? 115.125 94.243  137.461 1.00 43.51  ? 139 LEU D C   1 
ATOM   2141 O  O   . LEU B 2 139 ? 115.138 95.401  137.885 1.00 43.51  ? 139 LEU D O   1 
ATOM   2142 C  CB  . LEU B 2 139 ? 113.041 93.623  136.234 1.00 43.51  ? 139 LEU D CB  1 
ATOM   2143 C  CG  . LEU B 2 139 ? 111.889 92.650  135.993 1.00 43.51  ? 139 LEU D CG  1 
ATOM   2144 C  CD1 . LEU B 2 139 ? 111.148 93.015  134.719 1.00 43.51  ? 139 LEU D CD1 1 
ATOM   2145 C  CD2 . LEU B 2 139 ? 112.400 91.220  135.932 1.00 43.51  ? 139 LEU D CD2 1 
ATOM   2146 N  N   . PRO B 2 140 ? 116.213 93.677  136.945 1.00 39.86  ? 140 PRO D N   1 
ATOM   2147 C  CA  . PRO B 2 140 ? 117.453 94.447  136.804 1.00 39.86  ? 140 PRO D CA  1 
ATOM   2148 C  C   . PRO B 2 140 ? 117.364 95.427  135.643 1.00 39.86  ? 140 PRO D C   1 
ATOM   2149 O  O   . PRO B 2 140 ? 116.387 95.471  134.894 1.00 39.86  ? 140 PRO D O   1 
ATOM   2150 C  CB  . PRO B 2 140 ? 118.511 93.371  136.552 1.00 39.86  ? 140 PRO D CB  1 
ATOM   2151 C  CG  . PRO B 2 140 ? 117.755 92.258  135.920 1.00 39.86  ? 140 PRO D CG  1 
ATOM   2152 C  CD  . PRO B 2 140 ? 116.387 92.271  136.546 1.00 39.86  ? 140 PRO D CD  1 
ATOM   2153 N  N   . ASN B 2 141 ? 118.420 96.234  135.509 1.00 37.76  ? 141 ASN D N   1 
ATOM   2154 C  CA  . ASN B 2 141 ? 118.442 97.261  134.472 1.00 37.76  ? 141 ASN D CA  1 
ATOM   2155 C  C   . ASN B 2 141 ? 118.427 96.651  133.076 1.00 37.76  ? 141 ASN D C   1 
ATOM   2156 O  O   . ASN B 2 141 ? 117.716 97.137  132.190 1.00 37.76  ? 141 ASN D O   1 
ATOM   2157 C  CB  . ASN B 2 141 ? 119.666 98.157  134.651 1.00 37.76  ? 141 ASN D CB  1 
ATOM   2158 C  CG  . ASN B 2 141 ? 119.485 99.168  135.761 1.00 37.76  ? 141 ASN D CG  1 
ATOM   2159 O  OD1 . ASN B 2 141 ? 118.436 99.799  135.874 1.00 37.76  ? 141 ASN D OD1 1 
ATOM   2160 N  ND2 . ASN B 2 141 ? 120.508 99.325  136.591 1.00 37.76  ? 141 ASN D ND2 1 
ATOM   2161 N  N   . ILE B 2 142 ? 119.202 95.593  132.859 1.00 31.82  ? 142 ILE D N   1 
ATOM   2162 C  CA  . ILE B 2 142 ? 119.266 94.911  131.572 1.00 31.82  ? 142 ILE D CA  1 
ATOM   2163 C  C   . ILE B 2 142 ? 118.801 93.477  131.784 1.00 31.82  ? 142 ILE D C   1 
ATOM   2164 O  O   . ILE B 2 142 ? 119.348 92.759  132.631 1.00 31.82  ? 142 ILE D O   1 
ATOM   2165 C  CB  . ILE B 2 142 ? 120.679 94.961  130.970 1.00 31.82  ? 142 ILE D CB  1 
ATOM   2166 C  CG1 . ILE B 2 142 ? 120.842 96.220  130.119 1.00 31.82  ? 142 ILE D CG1 1 
ATOM   2167 C  CG2 . ILE B 2 142 ? 120.952 93.734  130.122 1.00 31.82  ? 142 ILE D CG2 1 
ATOM   2168 C  CD1 . ILE B 2 142 ? 122.277 96.577  129.829 1.00 31.82  ? 142 ILE D CD1 1 
ATOM   2169 N  N   . SER B 2 143 ? 117.789 93.068  131.030 1.00 33.40  ? 143 SER D N   1 
ATOM   2170 C  CA  . SER B 2 143 ? 117.174 91.765  131.247 1.00 33.40  ? 143 SER D CA  1 
ATOM   2171 C  C   . SER B 2 143 ? 117.847 90.710  130.378 1.00 33.40  ? 143 SER D C   1 
ATOM   2172 O  O   . SER B 2 143 ? 117.854 90.840  129.149 1.00 33.40  ? 143 SER D O   1 
ATOM   2173 C  CB  . SER B 2 143 ? 115.681 91.826  130.938 1.00 33.40  ? 143 SER D CB  1 
ATOM   2174 O  OG  . SER B 2 143 ? 115.102 93.012  131.450 1.00 33.40  ? 143 SER D OG  1 
ATOM   2175 N  N   . PRO B 2 144 ? 118.416 89.656  130.968 1.00 35.24  ? 144 PRO D N   1 
ATOM   2176 C  CA  . PRO B 2 144 ? 119.017 88.580  130.167 1.00 35.24  ? 144 PRO D CA  1 
ATOM   2177 C  C   . PRO B 2 144 ? 117.945 87.623  129.664 1.00 35.24  ? 144 PRO D C   1 
ATOM   2178 O  O   . PRO B 2 144 ? 117.064 87.208  130.419 1.00 35.24  ? 144 PRO D O   1 
ATOM   2179 C  CB  . PRO B 2 144 ? 119.967 87.895  131.155 1.00 35.24  ? 144 PRO D CB  1 
ATOM   2180 C  CG  . PRO B 2 144 ? 119.332 88.121  132.487 1.00 35.24  ? 144 PRO D CG  1 
ATOM   2181 C  CD  . PRO B 2 144 ? 118.577 89.429  132.414 1.00 35.24  ? 144 PRO D CD  1 
ATOM   2182 N  N   . VAL B 2 145 ? 118.021 87.276  128.382 1.00 33.74  ? 145 VAL D N   1 
ATOM   2183 C  CA  . VAL B 2 145 ? 117.075 86.367  127.744 1.00 33.74  ? 145 VAL D CA  1 
ATOM   2184 C  C   . VAL B 2 145 ? 117.857 85.169  127.227 1.00 33.74  ? 145 VAL D C   1 
ATOM   2185 O  O   . VAL B 2 145 ? 118.879 85.335  126.549 1.00 33.74  ? 145 VAL D O   1 
ATOM   2186 C  CB  . VAL B 2 145 ? 116.304 87.049  126.604 1.00 33.74  ? 145 VAL D CB  1 
ATOM   2187 C  CG1 . VAL B 2 145 ? 115.300 86.088  125.994 1.00 33.74  ? 145 VAL D CG1 1 
ATOM   2188 C  CG2 . VAL B 2 145 ? 115.612 88.302  127.108 1.00 33.74  ? 145 VAL D CG2 1 
ATOM   2189 N  N   . SER B 2 146 ? 117.382 83.969  127.543 1.00 39.12  ? 146 SER D N   1 
ATOM   2190 C  CA  . SER B 2 146 ? 118.033 82.730  127.135 1.00 39.12  ? 146 SER D CA  1 
ATOM   2191 C  C   . SER B 2 146 ? 117.107 81.965  126.199 1.00 39.12  ? 146 SER D C   1 
ATOM   2192 O  O   . SER B 2 146 ? 115.945 81.717  126.536 1.00 39.12  ? 146 SER D O   1 
ATOM   2193 C  CB  . SER B 2 146 ? 118.396 81.877  128.350 1.00 39.12  ? 146 SER D CB  1 
ATOM   2194 O  OG  . SER B 2 146 ? 119.012 80.665  127.954 1.00 39.12  ? 146 SER D OG  1 
ATOM   2195 N  N   . THR B 2 147 ? 117.625 81.594  125.028 1.00 42.00  ? 147 THR D N   1 
ATOM   2196 C  CA  . THR B 2 147 ? 116.856 80.828  124.056 1.00 42.00  ? 147 THR D CA  1 
ATOM   2197 C  C   . THR B 2 147 ? 117.211 79.348  124.049 1.00 42.00  ? 147 THR D C   1 
ATOM   2198 O  O   . THR B 2 147 ? 116.787 78.634  123.134 1.00 42.00  ? 147 THR D O   1 
ATOM   2199 C  CB  . THR B 2 147 ? 117.057 81.400  122.651 1.00 42.00  ? 147 THR D CB  1 
ATOM   2200 O  OG1 . THR B 2 147 ? 118.427 81.247  122.263 1.00 42.00  ? 147 THR D OG1 1 
ATOM   2201 C  CG2 . THR B 2 147 ? 116.691 82.873  122.621 1.00 42.00  ? 147 THR D CG2 1 
ATOM   2202 N  N   . ALA B 2 148 ? 117.980 78.875  125.032 1.00 50.03  ? 148 ALA D N   1 
ATOM   2203 C  CA  . ALA B 2 148 ? 118.370 77.470  125.058 1.00 50.03  ? 148 ALA D CA  1 
ATOM   2204 C  C   . ALA B 2 148 ? 117.169 76.551  125.241 1.00 50.03  ? 148 ALA D C   1 
ATOM   2205 O  O   . ALA B 2 148 ? 117.093 75.496  124.601 1.00 50.03  ? 148 ALA D O   1 
ATOM   2206 C  CB  . ALA B 2 148 ? 119.395 77.229  126.166 1.00 50.03  ? 148 ALA D CB  1 
ATOM   2207 N  N   . VAL B 2 149 ? 116.225 76.928  126.102 1.00 48.41  ? 149 VAL D N   1 
ATOM   2208 C  CA  . VAL B 2 149 ? 115.083 76.063  126.375 1.00 48.41  ? 149 VAL D CA  1 
ATOM   2209 C  C   . VAL B 2 149 ? 113.987 76.259  125.335 1.00 48.41  ? 149 VAL D C   1 
ATOM   2210 O  O   . VAL B 2 149 ? 113.445 75.286  124.800 1.00 48.41  ? 149 VAL D O   1 
ATOM   2211 C  CB  . VAL B 2 149 ? 114.561 76.312  127.801 1.00 48.41  ? 149 VAL D CB  1 
ATOM   2212 C  CG1 . VAL B 2 149 ? 113.365 75.420  128.092 1.00 48.41  ? 149 VAL D CG1 1 
ATOM   2213 C  CG2 . VAL B 2 149 ? 115.668 76.079  128.817 1.00 48.41  ? 149 VAL D CG2 1 
ATOM   2214 N  N   . SER B 2 150 ? 113.644 77.511  125.030 1.00 49.24  ? 150 SER D N   1 
ATOM   2215 C  CA  . SER B 2 150 ? 112.545 77.789  124.113 1.00 49.24  ? 150 SER D CA  1 
ATOM   2216 C  C   . SER B 2 150 ? 112.896 77.511  122.658 1.00 49.24  ? 150 SER D C   1 
ATOM   2217 O  O   . SER B 2 150 ? 111.989 77.246  121.861 1.00 49.24  ? 150 SER D O   1 
ATOM   2218 C  CB  . SER B 2 150 ? 112.095 79.243  124.261 1.00 49.24  ? 150 SER D CB  1 
ATOM   2219 O  OG  . SER B 2 150 ? 111.887 79.576  125.622 1.00 49.24  ? 150 SER D OG  1 
ATOM   2220 N  N   . GLN B 2 151 ? 114.179 77.581  122.295 1.00 48.75  ? 151 GLN D N   1 
ATOM   2221 C  CA  . GLN B 2 151 ? 114.644 77.334  120.932 1.00 48.75  ? 151 GLN D CA  1 
ATOM   2222 C  C   . GLN B 2 151 ? 114.021 78.308  119.939 1.00 48.75  ? 151 GLN D C   1 
ATOM   2223 O  O   . GLN B 2 151 ? 113.995 78.037  118.734 1.00 48.75  ? 151 GLN D O   1 
ATOM   2224 C  CB  . GLN B 2 151 ? 114.346 75.891  120.511 1.00 48.75  ? 151 GLN D CB  1 
ATOM   2225 C  CG  . GLN B 2 151 ? 114.879 74.835  121.465 1.00 48.75  ? 151 GLN D CG  1 
ATOM   2226 C  CD  . GLN B 2 151 ? 116.373 74.626  121.331 1.00 48.75  ? 151 GLN D CD  1 
ATOM   2227 O  OE1 . GLN B 2 151 ? 117.011 75.173  120.431 1.00 48.75  ? 151 GLN D OE1 1 
ATOM   2228 N  NE2 . GLN B 2 151 ? 116.941 73.827  122.227 1.00 48.75  ? 151 GLN D NE2 1 
ATOM   2229 N  N   . GLN B 2 152 ? 113.530 79.443  120.431 1.00 38.85  ? 152 GLN D N   1 
ATOM   2230 C  CA  . GLN B 2 152 ? 112.875 80.435  119.591 1.00 38.85  ? 152 GLN D CA  1 
ATOM   2231 C  C   . GLN B 2 152 ? 112.645 81.690  120.418 1.00 38.85  ? 152 GLN D C   1 
ATOM   2232 O  O   . GLN B 2 152 ? 112.350 81.619  121.613 1.00 38.85  ? 152 GLN D O   1 
ATOM   2233 C  CB  . GLN B 2 152 ? 111.552 79.902  119.024 1.00 38.85  ? 152 GLN D CB  1 
ATOM   2234 C  CG  . GLN B 2 152 ? 110.610 80.966  118.487 1.00 38.85  ? 152 GLN D CG  1 
ATOM   2235 C  CD  . GLN B 2 152 ? 109.396 80.375  117.802 1.00 38.85  ? 152 GLN D CD  1 
ATOM   2236 O  OE1 . GLN B 2 152 ? 108.525 81.100  117.323 1.00 38.85  ? 152 GLN D OE1 1 
ATOM   2237 N  NE2 . GLN B 2 152 ? 109.332 79.050  117.749 1.00 38.85  ? 152 GLN D NE2 1 
ATOM   2238 N  N   . VAL B 2 153 ? 112.797 82.844  119.769 1.00 28.51  ? 153 VAL D N   1 
ATOM   2239 C  CA  . VAL B 2 153 ? 112.521 84.129  120.398 1.00 28.51  ? 153 VAL D CA  1 
ATOM   2240 C  C   . VAL B 2 153 ? 112.021 85.085  119.324 1.00 28.51  ? 153 VAL D C   1 
ATOM   2241 O  O   . VAL B 2 153 ? 112.457 85.034  118.172 1.00 28.51  ? 153 VAL D O   1 
ATOM   2242 C  CB  . VAL B 2 153 ? 113.765 84.687  121.131 1.00 28.51  ? 153 VAL D CB  1 
ATOM   2243 C  CG1 . VAL B 2 153 ? 114.888 84.963  120.152 1.00 28.51  ? 153 VAL D CG1 1 
ATOM   2244 C  CG2 . VAL B 2 153 ? 113.412 85.939  121.919 1.00 28.51  ? 153 VAL D CG2 1 
ATOM   2245 N  N   . THR B 2 154 ? 111.086 85.949  119.705 1.00 42.30  ? 154 THR D N   1 
ATOM   2246 C  CA  . THR B 2 154 ? 110.454 86.885  118.787 1.00 42.30  ? 154 THR D CA  1 
ATOM   2247 C  C   . THR B 2 154 ? 110.657 88.311  119.280 1.00 42.30  ? 154 THR D C   1 
ATOM   2248 O  O   . THR B 2 154 ? 110.514 88.590  120.474 1.00 42.30  ? 154 THR D O   1 
ATOM   2249 C  CB  . THR B 2 154 ? 108.959 86.586  118.649 1.00 42.30  ? 154 THR D CB  1 
ATOM   2250 O  OG1 . THR B 2 154 ? 108.784 85.269  118.113 1.00 42.30  ? 154 THR D OG1 1 
ATOM   2251 C  CG2 . THR B 2 154 ? 108.291 87.592  117.729 1.00 42.30  ? 154 THR D CG2 1 
ATOM   2252 N  N   . VAL B 2 155 ? 110.991 89.210  118.358 1.00 51.63  ? 155 VAL D N   1 
ATOM   2253 C  CA  . VAL B 2 155 ? 111.231 90.613  118.668 1.00 51.63  ? 155 VAL D CA  1 
ATOM   2254 C  C   . VAL B 2 155 ? 110.279 91.460  117.837 1.00 51.63  ? 155 VAL D C   1 
ATOM   2255 O  O   . VAL B 2 155 ? 110.174 91.269  116.622 1.00 51.63  ? 155 VAL D O   1 
ATOM   2256 C  CB  . VAL B 2 155 ? 112.691 91.018  118.392 1.00 51.63  ? 155 VAL D CB  1 
ATOM   2257 C  CG1 . VAL B 2 155 ? 112.911 92.478  118.738 1.00 51.63  ? 155 VAL D CG1 1 
ATOM   2258 C  CG2 . VAL B 2 155 ? 113.644 90.131  119.172 1.00 51.63  ? 155 VAL D CG2 1 
ATOM   2259 N  N   . CYS B 2 156 ? 109.588 92.389  118.489 1.00 51.63  ? 156 CYS D N   1 
ATOM   2260 C  CA  . CYS B 2 156 ? 108.689 93.315  117.818 1.00 51.63  ? 156 CYS D CA  1 
ATOM   2261 C  C   . CYS B 2 156 ? 109.181 94.739  118.025 1.00 51.63  ? 156 CYS D C   1 
ATOM   2262 O  O   . CYS B 2 156 ? 109.930 95.024  118.962 1.00 51.63  ? 156 CYS D O   1 
ATOM   2263 C  CB  . CYS B 2 156 ? 107.254 93.178  118.333 1.00 51.63  ? 156 CYS D CB  1 
ATOM   2264 S  SG  . CYS B 2 156 ? 106.565 91.516  118.195 1.00 51.63  ? 156 CYS D SG  1 
ATOM   2265 N  N   . GLY B 2 157 ? 108.757 95.630  117.142 1.00 36.46  ? 157 GLY D N   1 
ATOM   2266 C  CA  . GLY B 2 157 ? 109.185 97.015  117.164 1.00 36.46  ? 157 GLY D CA  1 
ATOM   2267 C  C   . GLY B 2 157 ? 108.199 97.932  117.849 1.00 36.46  ? 157 GLY D C   1 
ATOM   2268 O  O   . GLY B 2 157 ? 107.464 97.531  118.757 1.00 36.46  ? 157 GLY D O   1 
ATOM   2269 N  N   . ASP B 2 158 ? 108.192 99.189  117.413 1.00 32.48  ? 158 ASP D N   1 
ATOM   2270 C  CA  . ASP B 2 158 ? 107.255 100.166 117.947 1.00 32.48  ? 158 ASP D CA  1 
ATOM   2271 C  C   . ASP B 2 158 ? 105.827 99.788  117.589 1.00 32.48  ? 158 ASP D C   1 
ATOM   2272 O  O   . ASP B 2 158 ? 105.552 99.300  116.490 1.00 32.48  ? 158 ASP D O   1 
ATOM   2273 C  CB  . ASP B 2 158 ? 107.575 101.556 117.399 1.00 32.48  ? 158 ASP D CB  1 
ATOM   2274 C  CG  . ASP B 2 158 ? 109.024 101.923 117.572 1.00 32.48  ? 158 ASP D CG  1 
ATOM   2275 O  OD1 . ASP B 2 158 ? 109.822 101.020 117.896 1.00 32.48  ? 158 ASP D OD1 1 
ATOM   2276 O  OD2 . ASP B 2 158 ? 109.366 103.108 117.380 1.00 32.48  ? 158 ASP D OD2 1 
ATOM   2277 N  N   . LEU B 2 159 ? 104.912 100.020 118.527 1.00 25.03  ? 159 LEU D N   1 
ATOM   2278 C  CA  . LEU B 2 159 ? 103.498 99.793  118.288 1.00 25.03  ? 159 LEU D CA  1 
ATOM   2279 C  C   . LEU B 2 159 ? 102.686 101.074 118.211 1.00 25.03  ? 159 LEU D C   1 
ATOM   2280 O  O   . LEU B 2 159 ? 101.790 101.160 117.364 1.00 25.03  ? 159 LEU D O   1 
ATOM   2281 C  CB  . LEU B 2 159 ? 102.909 98.888  119.381 1.00 25.03  ? 159 LEU D CB  1 
ATOM   2282 C  CG  . LEU B 2 159 ? 103.365 97.430  119.305 1.00 25.03  ? 159 LEU D CG  1 
ATOM   2283 C  CD1 . LEU B 2 159 ? 103.231 96.749  120.654 1.00 25.03  ? 159 LEU D CD1 1 
ATOM   2284 C  CD2 . LEU B 2 159 ? 102.584 96.677  118.246 1.00 25.03  ? 159 LEU D CD2 1 
ATOM   2285 N  N   . HIS B 2 160 ? 102.975 102.063 119.056 1.00 25.20  ? 160 HIS D N   1 
ATOM   2286 C  CA  . HIS B 2 160 ? 102.384 103.393 118.968 1.00 25.20  ? 160 HIS D CA  1 
ATOM   2287 C  C   . HIS B 2 160 ? 100.861 103.359 118.951 1.00 25.20  ? 160 HIS D C   1 
ATOM   2288 O  O   . HIS B 2 160 ? 100.228 104.079 118.174 1.00 25.20  ? 160 HIS D O   1 
ATOM   2289 C  CB  . HIS B 2 160 ? 102.908 104.117 117.728 1.00 25.20  ? 160 HIS D CB  1 
ATOM   2290 C  CG  . HIS B 2 160 ? 104.239 104.772 117.931 1.00 25.20  ? 160 HIS D CG  1 
ATOM   2291 N  ND1 . HIS B 2 160 ? 104.496 105.624 118.982 1.00 25.20  ? 160 HIS D ND1 1 
ATOM   2292 C  CD2 . HIS B 2 160 ? 105.386 104.701 117.215 1.00 25.20  ? 160 HIS D CD2 1 
ATOM   2293 C  CE1 . HIS B 2 160 ? 105.744 106.049 118.907 1.00 25.20  ? 160 HIS D CE1 1 
ATOM   2294 N  NE2 . HIS B 2 160 ? 106.306 105.504 117.843 1.00 25.20  ? 160 HIS D NE2 1 
ATOM   2295 N  N   . GLY B 2 161 ? 100.265 102.526 119.800 1.00 31.49  ? 161 GLY D N   1 
ATOM   2296 C  CA  . GLY B 2 161 ? 98.822  102.490 119.911 1.00 31.49  ? 161 GLY D CA  1 
ATOM   2297 C  C   . GLY B 2 161 ? 98.106  101.688 118.851 1.00 31.49  ? 161 GLY D C   1 
ATOM   2298 O  O   . GLY B 2 161 ? 96.872  101.681 118.832 1.00 31.49  ? 161 GLY D O   1 
ATOM   2299 N  N   . LYS B 2 162 ? 98.835  101.011 117.963 1.00 30.79  ? 162 LYS D N   1 
ATOM   2300 C  CA  . LYS B 2 162 ? 98.218  100.190 116.922 1.00 30.79  ? 162 LYS D CA  1 
ATOM   2301 C  C   . LYS B 2 162 ? 97.828  98.839  117.523 1.00 30.79  ? 162 LYS D C   1 
ATOM   2302 O  O   . LYS B 2 162 ? 98.542  97.839  117.427 1.00 30.79  ? 162 LYS D O   1 
ATOM   2303 C  CB  . LYS B 2 162 ? 99.161  100.028 115.738 1.00 30.79  ? 162 LYS D CB  1 
ATOM   2304 C  CG  . LYS B 2 162 ? 99.488  101.328 115.021 1.00 30.79  ? 162 LYS D CG  1 
ATOM   2305 C  CD  . LYS B 2 162 ? 98.241  101.967 114.439 1.00 30.79  ? 162 LYS D CD  1 
ATOM   2306 C  CE  . LYS B 2 162 ? 98.576  103.244 113.691 1.00 30.79  ? 162 LYS D CE  1 
ATOM   2307 N  NZ  . LYS B 2 162 ? 97.374  103.837 113.048 1.00 30.79  ? 162 LYS D NZ  1 
ATOM   2308 N  N   . LEU B 2 163 ? 96.656  98.829  118.163 1.00 34.36  ? 163 LEU D N   1 
ATOM   2309 C  CA  . LEU B 2 163 ? 96.180  97.612  118.816 1.00 34.36  ? 163 LEU D CA  1 
ATOM   2310 C  C   . LEU B 2 163 ? 95.934  96.502  117.803 1.00 34.36  ? 163 LEU D C   1 
ATOM   2311 O  O   . LEU B 2 163 ? 96.221  95.329  118.075 1.00 34.36  ? 163 LEU D O   1 
ATOM   2312 C  CB  . LEU B 2 163 ? 94.908  97.904  119.611 1.00 34.36  ? 163 LEU D CB  1 
ATOM   2313 C  CG  . LEU B 2 163 ? 94.199  96.689  120.212 1.00 34.36  ? 163 LEU D CG  1 
ATOM   2314 C  CD1 . LEU B 2 163 ? 95.101  95.982  121.206 1.00 34.36  ? 163 LEU D CD1 1 
ATOM   2315 C  CD2 . LEU B 2 163 ? 92.899  97.099  120.873 1.00 34.36  ? 163 LEU D CD2 1 
ATOM   2316 N  N   . ASP B 2 164 ? 95.397  96.851  116.632 1.00 43.85  ? 164 ASP D N   1 
ATOM   2317 C  CA  . ASP B 2 164 ? 95.129  95.842  115.615 1.00 43.85  ? 164 ASP D CA  1 
ATOM   2318 C  C   . ASP B 2 164 ? 96.409  95.165  115.142 1.00 43.85  ? 164 ASP D C   1 
ATOM   2319 O  O   . ASP B 2 164 ? 96.408  93.958  114.883 1.00 43.85  ? 164 ASP D O   1 
ATOM   2320 C  CB  . ASP B 2 164 ? 94.381  96.466  114.438 1.00 43.85  ? 164 ASP D CB  1 
ATOM   2321 C  CG  . ASP B 2 164 ? 95.045  97.723  113.929 1.00 43.85  ? 164 ASP D CG  1 
ATOM   2322 O  OD1 . ASP B 2 164 ? 95.142  98.696  114.704 1.00 43.85  ? 164 ASP D OD1 1 
ATOM   2323 O  OD2 . ASP B 2 164 ? 95.467  97.742  112.754 1.00 43.85  ? 164 ASP D OD2 1 
ATOM   2324 N  N   . ASP B 2 165 ? 97.508  95.915  115.029 1.00 37.42  ? 165 ASP D N   1 
ATOM   2325 C  CA  . ASP B 2 165 ? 98.785  95.303  114.674 1.00 37.42  ? 165 ASP D CA  1 
ATOM   2326 C  C   . ASP B 2 165 ? 99.258  94.313  115.731 1.00 37.42  ? 165 ASP D C   1 
ATOM   2327 O  O   . ASP B 2 165 ? 99.743  93.227  115.386 1.00 37.42  ? 165 ASP D O   1 
ATOM   2328 C  CB  . ASP B 2 165 ? 99.843  96.384  114.457 1.00 37.42  ? 165 ASP D CB  1 
ATOM   2329 C  CG  . ASP B 2 165 ? 99.480  97.335  113.337 1.00 37.42  ? 165 ASP D CG  1 
ATOM   2330 O  OD1 . ASP B 2 165 ? 98.277  97.458  113.027 1.00 37.42  ? 165 ASP D OD1 1 
ATOM   2331 O  OD2 . ASP B 2 165 ? 100.395 97.960  112.763 1.00 37.42  ? 165 ASP D OD2 1 
ATOM   2332 N  N   . LEU B 2 166 ? 99.125  94.662  117.013 1.00 31.68  ? 166 LEU D N   1 
ATOM   2333 C  CA  . LEU B 2 166 ? 99.501  93.736  118.076 1.00 31.68  ? 166 LEU D CA  1 
ATOM   2334 C  C   . LEU B 2 166 ? 98.637  92.482  118.042 1.00 31.68  ? 166 LEU D C   1 
ATOM   2335 O  O   . LEU B 2 166 ? 99.139  91.366  118.225 1.00 31.68  ? 166 LEU D O   1 
ATOM   2336 C  CB  . LEU B 2 166 ? 99.391  94.425  119.435 1.00 31.68  ? 166 LEU D CB  1 
ATOM   2337 C  CG  . LEU B 2 166 ? 99.558  93.528  120.661 1.00 31.68  ? 166 LEU D CG  1 
ATOM   2338 C  CD1 . LEU B 2 166 ? 100.949 92.922  120.689 1.00 31.68  ? 166 LEU D CD1 1 
ATOM   2339 C  CD2 . LEU B 2 166 ? 99.281  94.304  121.935 1.00 31.68  ? 166 LEU D CD2 1 
ATOM   2340 N  N   . LEU B 2 167 ? 97.333  92.645  117.809 1.00 36.01  ? 167 LEU D N   1 
ATOM   2341 C  CA  . LEU B 2 167 ? 96.451  91.485  117.727 1.00 36.01  ? 167 LEU D CA  1 
ATOM   2342 C  C   . LEU B 2 167 ? 96.794  90.615  116.524 1.00 36.01  ? 167 LEU D C   1 
ATOM   2343 O  O   . LEU B 2 167 ? 96.733  89.384  116.608 1.00 36.01  ? 167 LEU D O   1 
ATOM   2344 C  CB  . LEU B 2 167 ? 94.993  91.934  117.676 1.00 36.01  ? 167 LEU D CB  1 
ATOM   2345 C  CG  . LEU B 2 167 ? 94.461  92.510  118.989 1.00 36.01  ? 167 LEU D CG  1 
ATOM   2346 C  CD1 . LEU B 2 167 ? 93.076  93.100  118.803 1.00 36.01  ? 167 LEU D CD1 1 
ATOM   2347 C  CD2 . LEU B 2 167 ? 94.451  91.445  120.070 1.00 36.01  ? 167 LEU D CD2 1 
ATOM   2348 N  N   . VAL B 2 168 ? 97.157  91.234  115.398 1.00 35.48  ? 168 VAL D N   1 
ATOM   2349 C  CA  . VAL B 2 168 ? 97.571  90.470  114.224 1.00 35.48  ? 168 VAL D CA  1 
ATOM   2350 C  C   . VAL B 2 168 ? 98.833  89.673  114.525 1.00 35.48  ? 168 VAL D C   1 
ATOM   2351 O  O   . VAL B 2 168 ? 98.941  88.492  114.169 1.00 35.48  ? 168 VAL D O   1 
ATOM   2352 C  CB  . VAL B 2 168 ? 97.768  91.411  113.019 1.00 35.48  ? 168 VAL D CB  1 
ATOM   2353 C  CG1 . VAL B 2 168 ? 98.625  90.747  111.957 1.00 35.48  ? 168 VAL D CG1 1 
ATOM   2354 C  CG2 . VAL B 2 168 ? 96.425  91.815  112.441 1.00 35.48  ? 168 VAL D CG2 1 
ATOM   2355 N  N   . VAL B 2 169 ? 99.806  90.304  115.188 1.00 35.97  ? 169 VAL D N   1 
ATOM   2356 C  CA  . VAL B 2 169 ? 101.038 89.604  115.545 1.00 35.97  ? 169 VAL D CA  1 
ATOM   2357 C  C   . VAL B 2 169 ? 100.731 88.427  116.462 1.00 35.97  ? 169 VAL D C   1 
ATOM   2358 O  O   . VAL B 2 169 ? 101.246 87.318  116.273 1.00 35.97  ? 169 VAL D O   1 
ATOM   2359 C  CB  . VAL B 2 169 ? 102.040 90.576  116.194 1.00 35.97  ? 169 VAL D CB  1 
ATOM   2360 C  CG1 . VAL B 2 169 ? 103.195 89.810  116.816 1.00 35.97  ? 169 VAL D CG1 1 
ATOM   2361 C  CG2 . VAL B 2 169 ? 102.553 91.568  115.171 1.00 35.97  ? 169 VAL D CG2 1 
ATOM   2362 N  N   . LEU B 2 170 ? 99.881  88.651  117.467 1.00 34.66  ? 170 LEU D N   1 
ATOM   2363 C  CA  . LEU B 2 170 ? 99.540  87.582  118.401 1.00 34.66  ? 170 LEU D CA  1 
ATOM   2364 C  C   . LEU B 2 170 ? 98.825  86.435  117.697 1.00 34.66  ? 170 LEU D C   1 
ATOM   2365 O  O   . LEU B 2 170 ? 99.107  85.262  117.965 1.00 34.66  ? 170 LEU D O   1 
ATOM   2366 C  CB  . LEU B 2 170 ? 98.681  88.130  119.539 1.00 34.66  ? 170 LEU D CB  1 
ATOM   2367 C  CG  . LEU B 2 170 ? 99.417  88.948  120.599 1.00 34.66  ? 170 LEU D CG  1 
ATOM   2368 C  CD1 . LEU B 2 170 ? 98.430  89.615  121.539 1.00 34.66  ? 170 LEU D CD1 1 
ATOM   2369 C  CD2 . LEU B 2 170 ? 100.383 88.069  121.370 1.00 34.66  ? 170 LEU D CD2 1 
ATOM   2370 N  N   . HIS B 2 171 ? 97.891  86.753  116.800 1.00 44.80  ? 171 HIS D N   1 
ATOM   2371 C  CA  . HIS B 2 171 ? 97.160  85.710  116.088 1.00 44.80  ? 171 HIS D CA  1 
ATOM   2372 C  C   . HIS B 2 171 ? 98.084  84.910  115.179 1.00 44.80  ? 171 HIS D C   1 
ATOM   2373 O  O   . HIS B 2 171 ? 97.970  83.683  115.087 1.00 44.80  ? 171 HIS D O   1 
ATOM   2374 C  CB  . HIS B 2 171 ? 96.017  86.330  115.283 1.00 44.80  ? 171 HIS D CB  1 
ATOM   2375 C  CG  . HIS B 2 171 ? 95.368  85.380  114.326 1.00 44.80  ? 171 HIS D CG  1 
ATOM   2376 N  ND1 . HIS B 2 171 ? 95.163  84.049  114.620 1.00 44.80  ? 171 HIS D ND1 1 
ATOM   2377 C  CD2 . HIS B 2 171 ? 94.878  85.568  113.078 1.00 44.80  ? 171 HIS D CD2 1 
ATOM   2378 C  CE1 . HIS B 2 171 ? 94.575  83.458  113.596 1.00 44.80  ? 171 HIS D CE1 1 
ATOM   2379 N  NE2 . HIS B 2 171 ? 94.391  84.358  112.646 1.00 44.80  ? 171 HIS D NE2 1 
ATOM   2380 N  N   . LYS B 2 172 ? 99.007  85.589  114.494 1.00 42.36  ? 172 LYS D N   1 
ATOM   2381 C  CA  . LYS B 2 172 ? 99.862  84.894  113.538 1.00 42.36  ? 172 LYS D CA  1 
ATOM   2382 C  C   . LYS B 2 172 ? 100.940 84.074  114.236 1.00 42.36  ? 172 LYS D C   1 
ATOM   2383 O  O   . LYS B 2 172 ? 101.315 82.999  113.756 1.00 42.36  ? 172 LYS D O   1 
ATOM   2384 C  CB  . LYS B 2 172 ? 100.492 85.898  112.574 1.00 42.36  ? 172 LYS D CB  1 
ATOM   2385 C  CG  . LYS B 2 172 ? 101.371 85.265  111.513 1.00 42.36  ? 172 LYS D CG  1 
ATOM   2386 C  CD  . LYS B 2 172 ? 101.843 86.296  110.508 1.00 42.36  ? 172 LYS D CD  1 
ATOM   2387 C  CE  . LYS B 2 172 ? 100.734 86.643  109.537 1.00 42.36  ? 172 LYS D CE  1 
ATOM   2388 N  NZ  . LYS B 2 172 ? 100.604 85.606  108.479 1.00 42.36  ? 172 LYS D NZ  1 
ATOM   2389 N  N   . ASN B 2 173 ? 101.448 84.556  115.370 1.00 38.97  ? 173 ASN D N   1 
ATOM   2390 C  CA  . ASN B 2 173 ? 102.571 83.916  116.039 1.00 38.97  ? 173 ASN D CA  1 
ATOM   2391 C  C   . ASN B 2 173 ? 102.189 83.206  117.331 1.00 38.97  ? 173 ASN D C   1 
ATOM   2392 O  O   . ASN B 2 173 ? 103.048 82.562  117.942 1.00 38.97  ? 173 ASN D O   1 
ATOM   2393 C  CB  . ASN B 2 173 ? 103.666 84.949  116.324 1.00 38.97  ? 173 ASN D CB  1 
ATOM   2394 C  CG  . ASN B 2 173 ? 105.042 84.327  116.415 1.00 38.97  ? 173 ASN D CG  1 
ATOM   2395 O  OD1 . ASN B 2 173 ? 105.646 83.979  115.401 1.00 38.97  ? 173 ASN D OD1 1 
ATOM   2396 N  ND2 . ASN B 2 173 ? 105.546 84.183  117.634 1.00 38.97  ? 173 ASN D ND2 1 
ATOM   2397 N  N   . GLY B 2 174 ? 100.940 83.302  117.763 1.00 35.77  ? 174 GLY D N   1 
ATOM   2398 C  CA  . GLY B 2 174 ? 100.506 82.645  118.977 1.00 35.77  ? 174 GLY D CA  1 
ATOM   2399 C  C   . GLY B 2 174 ? 100.773 83.479  120.219 1.00 35.77  ? 174 GLY D C   1 
ATOM   2400 O  O   . GLY B 2 174 ? 101.581 84.405  120.228 1.00 35.77  ? 174 GLY D O   1 
ATOM   2401 N  N   . LEU B 2 175 ? 100.066 83.131  121.291 1.00 32.69  ? 175 LEU D N   1 
ATOM   2402 C  CA  . LEU B 2 175 ? 100.225 83.843  122.548 1.00 32.69  ? 175 LEU D CA  1 
ATOM   2403 C  C   . LEU B 2 175 ? 101.596 83.544  123.153 1.00 32.69  ? 175 LEU D C   1 
ATOM   2404 O  O   . LEU B 2 175 ? 102.140 82.451  122.968 1.00 32.69  ? 175 LEU D O   1 
ATOM   2405 C  CB  . LEU B 2 175 ? 99.122  83.450  123.528 1.00 32.69  ? 175 LEU D CB  1 
ATOM   2406 C  CG  . LEU B 2 175 ? 97.698  83.865  123.155 1.00 32.69  ? 175 LEU D CG  1 
ATOM   2407 C  CD1 . LEU B 2 175 ? 96.698  83.271  124.129 1.00 32.69  ? 175 LEU D CD1 1 
ATOM   2408 C  CD2 . LEU B 2 175 ? 97.576  85.377  123.119 1.00 32.69  ? 175 LEU D CD2 1 
ATOM   2409 N  N   . PRO B 2 176 ? 102.183 84.502  123.871 1.00 26.46  ? 176 PRO D N   1 
ATOM   2410 C  CA  . PRO B 2 176 ? 103.482 84.255  124.506 1.00 26.46  ? 176 PRO D CA  1 
ATOM   2411 C  C   . PRO B 2 176 ? 103.402 83.129  125.524 1.00 26.46  ? 176 PRO D C   1 
ATOM   2412 O  O   . PRO B 2 176 ? 102.397 82.962  126.218 1.00 26.46  ? 176 PRO D O   1 
ATOM   2413 C  CB  . PRO B 2 176 ? 103.810 85.594  125.174 1.00 26.46  ? 176 PRO D CB  1 
ATOM   2414 C  CG  . PRO B 2 176 ? 102.996 86.598  124.439 1.00 26.46  ? 176 PRO D CG  1 
ATOM   2415 C  CD  . PRO B 2 176 ? 101.738 85.893  124.047 1.00 26.46  ? 176 PRO D CD  1 
ATOM   2416 N  N   . SER B 2 177 ? 104.480 82.356  125.610 1.00 31.31  ? 177 SER D N   1 
ATOM   2417 C  CA  . SER B 2 177 ? 104.564 81.235  126.537 1.00 31.31  ? 177 SER D CA  1 
ATOM   2418 C  C   . SER B 2 177 ? 106.032 80.870  126.697 1.00 31.31  ? 177 SER D C   1 
ATOM   2419 O  O   . SER B 2 177 ? 106.912 81.476  126.081 1.00 31.31  ? 177 SER D O   1 
ATOM   2420 C  CB  . SER B 2 177 ? 103.749 80.034  126.050 1.00 31.31  ? 177 SER D CB  1 
ATOM   2421 O  OG  . SER B 2 177 ? 102.366 80.228  126.286 1.00 31.31  ? 177 SER D OG  1 
ATOM   2422 N  N   . SER B 2 178 ? 106.284 79.860  127.532 1.00 42.44  ? 178 SER D N   1 
ATOM   2423 C  CA  . SER B 2 178 ? 107.655 79.436  127.795 1.00 42.44  ? 178 SER D CA  1 
ATOM   2424 C  C   . SER B 2 178 ? 108.352 78.917  126.545 1.00 42.44  ? 178 SER D C   1 
ATOM   2425 O  O   . SER B 2 178 ? 109.586 78.927  126.489 1.00 42.44  ? 178 SER D O   1 
ATOM   2426 C  CB  . SER B 2 178 ? 107.674 78.364  128.885 1.00 42.44  ? 178 SER D CB  1 
ATOM   2427 O  OG  . SER B 2 178 ? 107.896 78.939  130.161 1.00 42.44  ? 178 SER D OG  1 
ATOM   2428 N  N   . SER B 2 179 ? 107.597 78.463  125.548 1.00 42.77  ? 179 SER D N   1 
ATOM   2429 C  CA  . SER B 2 179 ? 108.165 78.004  124.289 1.00 42.77  ? 179 SER D CA  1 
ATOM   2430 C  C   . SER B 2 179 ? 108.063 79.042  123.179 1.00 42.77  ? 179 SER D C   1 
ATOM   2431 O  O   . SER B 2 179 ? 108.359 78.722  122.023 1.00 42.77  ? 179 SER D O   1 
ATOM   2432 C  CB  . SER B 2 179 ? 107.482 76.708  123.843 1.00 42.77  ? 179 SER D CB  1 
ATOM   2433 O  OG  . SER B 2 179 ? 106.107 76.922  123.578 1.00 42.77  ? 179 SER D OG  1 
ATOM   2434 N  N   . ASN B 2 180 ? 107.654 80.270  123.497 1.00 33.89  ? 180 ASN D N   1 
ATOM   2435 C  CA  . ASN B 2 180 ? 107.504 81.319  122.496 1.00 33.89  ? 180 ASN D CA  1 
ATOM   2436 C  C   . ASN B 2 180 ? 107.589 82.695  123.148 1.00 33.89  ? 180 ASN D C   1 
ATOM   2437 O  O   . ASN B 2 180 ? 106.580 83.407  123.221 1.00 33.89  ? 180 ASN D O   1 
ATOM   2438 C  CB  . ASN B 2 180 ? 106.172 81.157  121.760 1.00 33.89  ? 180 ASN D CB  1 
ATOM   2439 C  CG  . ASN B 2 180 ? 106.134 81.908  120.447 1.00 33.89  ? 180 ASN D CG  1 
ATOM   2440 O  OD1 . ASN B 2 180 ? 106.195 83.136  120.419 1.00 33.89  ? 180 ASN D OD1 1 
ATOM   2441 N  ND2 . ASN B 2 180 ? 106.027 81.172  119.348 1.00 33.89  ? 180 ASN D ND2 1 
ATOM   2442 N  N   . PRO B 2 181 ? 108.760 83.106  123.630 1.00 33.23  ? 181 PRO D N   1 
ATOM   2443 C  CA  . PRO B 2 181 ? 108.860 84.397  124.320 1.00 33.23  ? 181 PRO D CA  1 
ATOM   2444 C  C   . PRO B 2 181 ? 108.768 85.571  123.357 1.00 33.23  ? 181 PRO D C   1 
ATOM   2445 O  O   . PRO B 2 181 ? 108.825 85.423  122.135 1.00 33.23  ? 181 PRO D O   1 
ATOM   2446 C  CB  . PRO B 2 181 ? 110.237 84.336  124.988 1.00 33.23  ? 181 PRO D CB  1 
ATOM   2447 C  CG  . PRO B 2 181 ? 111.012 83.386  124.155 1.00 33.23  ? 181 PRO D CG  1 
ATOM   2448 C  CD  . PRO B 2 181 ? 110.033 82.367  123.654 1.00 33.23  ? 181 PRO D CD  1 
ATOM   2449 N  N   . TYR B 2 182 ? 108.618 86.761  123.938 1.00 35.66  ? 182 TYR D N   1 
ATOM   2450 C  CA  . TYR B 2 182 ? 108.478 88.003  123.191 1.00 35.66  ? 182 TYR D CA  1 
ATOM   2451 C  C   . TYR B 2 182 ? 109.377 89.072  123.794 1.00 35.66  ? 182 TYR D C   1 
ATOM   2452 O  O   . TYR B 2 182 ? 109.680 89.036  124.989 1.00 35.66  ? 182 TYR D O   1 
ATOM   2453 C  CB  . TYR B 2 182 ? 107.031 88.502  123.202 1.00 35.66  ? 182 TYR D CB  1 
ATOM   2454 C  CG  . TYR B 2 182 ? 106.150 87.911  122.130 1.00 35.66  ? 182 TYR D CG  1 
ATOM   2455 C  CD1 . TYR B 2 182 ? 105.845 86.559  122.121 1.00 35.66  ? 182 TYR D CD1 1 
ATOM   2456 C  CD2 . TYR B 2 182 ? 105.610 88.710  121.133 1.00 35.66  ? 182 TYR D CD2 1 
ATOM   2457 C  CE1 . TYR B 2 182 ? 105.037 86.018  121.146 1.00 35.66  ? 182 TYR D CE1 1 
ATOM   2458 C  CE2 . TYR B 2 182 ? 104.800 88.178  120.153 1.00 35.66  ? 182 TYR D CE2 1 
ATOM   2459 C  CZ  . TYR B 2 182 ? 104.517 86.831  120.165 1.00 35.66  ? 182 TYR D CZ  1 
ATOM   2460 O  OH  . TYR B 2 182 ? 103.711 86.294  119.192 1.00 35.66  ? 182 TYR D OH  1 
ATOM   2461 N  N   . VAL B 2 183 ? 109.798 90.022  122.963 1.00 51.63  ? 183 VAL D N   1 
ATOM   2462 C  CA  . VAL B 2 183 ? 110.571 91.183  123.397 1.00 51.63  ? 183 VAL D CA  1 
ATOM   2463 C  C   . VAL B 2 183 ? 110.025 92.404  122.671 1.00 51.63  ? 183 VAL D C   1 
ATOM   2464 O  O   . VAL B 2 183 ? 110.285 92.589  121.477 1.00 51.63  ? 183 VAL D O   1 
ATOM   2465 C  CB  . VAL B 2 183 ? 112.074 91.017  123.120 1.00 51.63  ? 183 VAL D CB  1 
ATOM   2466 C  CG1 . VAL B 2 183 ? 112.822 92.276  123.515 1.00 51.63  ? 183 VAL D CG1 1 
ATOM   2467 C  CG2 . VAL B 2 183 ? 112.633 89.819  123.867 1.00 51.63  ? 183 VAL D CG2 1 
ATOM   2468 N  N   . PHE B 2 184 ? 109.272 93.235  123.387 1.00 51.63  ? 184 PHE D N   1 
ATOM   2469 C  CA  . PHE B 2 184 ? 108.670 94.435  122.818 1.00 51.63  ? 184 PHE D CA  1 
ATOM   2470 C  C   . PHE B 2 184 ? 109.620 95.608  123.026 1.00 51.63  ? 184 PHE D C   1 
ATOM   2471 O  O   . PHE B 2 184 ? 109.960 95.941  124.166 1.00 51.63  ? 184 PHE D O   1 
ATOM   2472 C  CB  . PHE B 2 184 ? 107.310 94.710  123.456 1.00 51.63  ? 184 PHE D CB  1 
ATOM   2473 C  CG  . PHE B 2 184 ? 106.296 93.632  123.199 1.00 51.63  ? 184 PHE D CG  1 
ATOM   2474 C  CD1 . PHE B 2 184 ? 105.541 93.635  122.040 1.00 51.63  ? 184 PHE D CD1 1 
ATOM   2475 C  CD2 . PHE B 2 184 ? 106.108 92.610  124.111 1.00 51.63  ? 184 PHE D CD2 1 
ATOM   2476 C  CE1 . PHE B 2 184 ? 104.611 92.643  121.802 1.00 51.63  ? 184 PHE D CE1 1 
ATOM   2477 C  CE2 . PHE B 2 184 ? 105.181 91.615  123.877 1.00 51.63  ? 184 PHE D CE2 1 
ATOM   2478 C  CZ  . PHE B 2 184 ? 104.432 91.632  122.721 1.00 51.63  ? 184 PHE D CZ  1 
ATOM   2479 N  N   . ASN B 2 185 ? 110.042 96.228  121.930 1.00 43.42  ? 185 ASN D N   1 
ATOM   2480 C  CA  . ASN B 2 185 ? 111.138 97.200  121.944 1.00 43.42  ? 185 ASN D CA  1 
ATOM   2481 C  C   . ASN B 2 185 ? 110.645 98.640  122.061 1.00 43.42  ? 185 ASN D C   1 
ATOM   2482 O  O   . ASN B 2 185 ? 110.986 99.490  121.242 1.00 43.42  ? 185 ASN D O   1 
ATOM   2483 C  CB  . ASN B 2 185 ? 111.996 97.019  120.699 1.00 43.42  ? 185 ASN D CB  1 
ATOM   2484 C  CG  . ASN B 2 185 ? 113.456 97.305  120.956 1.00 43.42  ? 185 ASN D CG  1 
ATOM   2485 O  OD1 . ASN B 2 185 ? 113.911 97.288  122.098 1.00 43.42  ? 185 ASN D OD1 1 
ATOM   2486 N  ND2 . ASN B 2 185 ? 114.205 97.560  119.891 1.00 43.42  ? 185 ASN D ND2 1 
ATOM   2487 N  N   . GLY B 2 186 ? 109.842 98.941  123.078 1.00 33.56  ? 186 GLY D N   1 
ATOM   2488 C  CA  . GLY B 2 186 ? 109.534 100.319 123.409 1.00 33.56  ? 186 GLY D CA  1 
ATOM   2489 C  C   . GLY B 2 186 ? 108.496 100.965 122.511 1.00 33.56  ? 186 GLY D C   1 
ATOM   2490 O  O   . GLY B 2 186 ? 107.992 100.382 121.551 1.00 33.56  ? 186 GLY D O   1 
ATOM   2491 N  N   . ASP B 2 187 ? 108.183 102.217 122.846 1.00 34.80  ? 187 ASP D N   1 
ATOM   2492 C  CA  . ASP B 2 187 ? 107.196 103.030 122.136 1.00 34.80  ? 187 ASP D CA  1 
ATOM   2493 C  C   . ASP B 2 187 ? 105.845 102.319 122.068 1.00 34.80  ? 187 ASP D C   1 
ATOM   2494 O  O   . ASP B 2 187 ? 105.342 101.970 121.001 1.00 34.80  ? 187 ASP D O   1 
ATOM   2495 C  CB  . ASP B 2 187 ? 107.693 103.404 120.738 1.00 34.80  ? 187 ASP D CB  1 
ATOM   2496 C  CG  . ASP B 2 187 ? 109.009 104.149 120.769 1.00 34.80  ? 187 ASP D CG  1 
ATOM   2497 O  OD1 . ASP B 2 187 ? 109.658 104.154 121.834 1.00 34.80  ? 187 ASP D OD1 1 
ATOM   2498 O  OD2 . ASP B 2 187 ? 109.392 104.732 119.733 1.00 34.80  ? 187 ASP D OD2 1 
ATOM   2499 N  N   . PHE B 2 188 ? 105.260 102.108 123.247 1.00 32.29  ? 188 PHE D N   1 
ATOM   2500 C  CA  . PHE B 2 188 ? 104.002 101.374 123.320 1.00 32.29  ? 188 PHE D CA  1 
ATOM   2501 C  C   . PHE B 2 188 ? 102.798 102.268 123.057 1.00 32.29  ? 188 PHE D C   1 
ATOM   2502 O  O   . PHE B 2 188 ? 101.695 101.760 122.830 1.00 32.29  ? 188 PHE D O   1 
ATOM   2503 C  CB  . PHE B 2 188 ? 103.848 100.719 124.693 1.00 32.29  ? 188 PHE D CB  1 
ATOM   2504 C  CG  . PHE B 2 188 ? 104.960 99.782  125.056 1.00 32.29  ? 188 PHE D CG  1 
ATOM   2505 C  CD1 . PHE B 2 188 ? 105.676 99.114  124.081 1.00 32.29  ? 188 PHE D CD1 1 
ATOM   2506 C  CD2 . PHE B 2 188 ? 105.285 99.566  126.383 1.00 32.29  ? 188 PHE D CD2 1 
ATOM   2507 C  CE1 . PHE B 2 188 ? 106.697 98.254  124.424 1.00 32.29  ? 188 PHE D CE1 1 
ATOM   2508 C  CE2 . PHE B 2 188 ? 106.304 98.708  126.730 1.00 32.29  ? 188 PHE D CE2 1 
ATOM   2509 C  CZ  . PHE B 2 188 ? 107.011 98.051  125.750 1.00 32.29  ? 188 PHE D CZ  1 
ATOM   2510 N  N   . VAL B 2 189 ? 102.975 103.588 123.085 1.00 31.16  ? 189 VAL D N   1 
ATOM   2511 C  CA  . VAL B 2 189 ? 101.833 104.467 123.305 1.00 31.16  ? 189 VAL D CA  1 
ATOM   2512 C  C   . VAL B 2 189 ? 102.071 105.830 122.652 1.00 31.16  ? 189 VAL D C   1 
ATOM   2513 O  O   . VAL B 2 189 ? 103.168 106.099 122.155 1.00 31.16  ? 189 VAL D O   1 
ATOM   2514 C  CB  . VAL B 2 189 ? 101.585 104.564 124.828 1.00 31.16  ? 189 VAL D CB  1 
ATOM   2515 C  CG1 . VAL B 2 189 ? 102.888 104.862 125.565 1.00 31.16  ? 189 VAL D CG1 1 
ATOM   2516 C  CG2 . VAL B 2 189 ? 100.469 105.523 125.214 1.00 31.16  ? 189 VAL D CG2 1 
ATOM   2517 N  N   . ASP B 2 190 ? 101.014 106.650 122.583 1.00 35.79  ? 190 ASP D N   1 
ATOM   2518 C  CA  . ASP B 2 190 ? 101.000 108.102 122.375 1.00 35.79  ? 190 ASP D CA  1 
ATOM   2519 C  C   . ASP B 2 190 ? 101.116 108.559 120.924 1.00 35.79  ? 190 ASP D C   1 
ATOM   2520 O  O   . ASP B 2 190 ? 101.317 109.751 120.672 1.00 35.79  ? 190 ASP D O   1 
ATOM   2521 C  CB  . ASP B 2 190 ? 102.060 108.797 123.263 1.00 35.79  ? 190 ASP D CB  1 
ATOM   2522 C  CG  . ASP B 2 190 ? 103.490 108.780 122.694 1.00 35.79  ? 190 ASP D CG  1 
ATOM   2523 O  OD1 . ASP B 2 190 ? 104.424 108.866 123.518 1.00 35.79  ? 190 ASP D OD1 1 
ATOM   2524 O  OD2 . ASP B 2 190 ? 103.719 108.703 121.470 1.00 35.79  ? 190 ASP D OD2 1 
ATOM   2525 N  N   . ARG B 2 191 ? 100.972 107.650 119.961 1.00 31.39  ? 191 ARG D N   1 
ATOM   2526 C  CA  . ARG B 2 191 ? 100.912 108.094 118.573 1.00 31.39  ? 191 ARG D CA  1 
ATOM   2527 C  C   . ARG B 2 191 ? 99.595  107.728 117.900 1.00 31.39  ? 191 ARG D C   1 
ATOM   2528 O  O   . ARG B 2 191 ? 99.116  108.490 117.054 1.00 31.39  ? 191 ARG D O   1 
ATOM   2529 C  CB  . ARG B 2 191 ? 102.082 107.518 117.779 1.00 31.39  ? 191 ARG D CB  1 
ATOM   2530 C  CG  . ARG B 2 191 ? 102.286 108.157 116.415 1.00 31.39  ? 191 ARG D CG  1 
ATOM   2531 C  CD  . ARG B 2 191 ? 102.338 109.675 116.509 1.00 31.39  ? 191 ARG D CD  1 
ATOM   2532 N  NE  . ARG B 2 191 ? 102.822 110.294 115.280 1.00 31.39  ? 191 ARG D NE  1 
ATOM   2533 C  CZ  . ARG B 2 191 ? 102.167 110.303 114.126 1.00 31.39  ? 191 ARG D CZ  1 
ATOM   2534 N  NH1 . ARG B 2 191 ? 100.970 109.752 114.004 1.00 31.39  ? 191 ARG D NH1 1 
ATOM   2535 N  NH2 . ARG B 2 191 ? 102.724 110.887 113.069 1.00 31.39  ? 191 ARG D NH2 1 
ATOM   2536 N  N   . GLY B 2 192 ? 99.000  106.590 118.256 1.00 29.84  ? 192 GLY D N   1 
ATOM   2537 C  CA  . GLY B 2 192 ? 97.743  106.158 117.693 1.00 29.84  ? 192 GLY D CA  1 
ATOM   2538 C  C   . GLY B 2 192 ? 96.554  106.652 118.504 1.00 29.84  ? 192 GLY D C   1 
ATOM   2539 O  O   . GLY B 2 192 ? 96.685  107.389 119.480 1.00 29.84  ? 192 GLY D O   1 
ATOM   2540 N  N   . LYS B 2 193 ? 95.369  106.222 118.072 1.00 31.56  ? 193 LYS D N   1 
ATOM   2541 C  CA  . LYS B 2 193 ? 94.130  106.605 118.735 1.00 31.56  ? 193 LYS D CA  1 
ATOM   2542 C  C   . LYS B 2 193 ? 93.697  105.619 119.811 1.00 31.56  ? 193 LYS D C   1 
ATOM   2543 O  O   . LYS B 2 193 ? 92.681  105.860 120.472 1.00 31.56  ? 193 LYS D O   1 
ATOM   2544 C  CB  . LYS B 2 193 ? 93.007  106.754 117.704 1.00 31.56  ? 193 LYS D CB  1 
ATOM   2545 C  CG  . LYS B 2 193 ? 93.199  107.906 116.733 1.00 31.56  ? 193 LYS D CG  1 
ATOM   2546 C  CD  . LYS B 2 193 ? 93.185  109.244 117.453 1.00 31.56  ? 193 LYS D CD  1 
ATOM   2547 C  CE  . LYS B 2 193 ? 93.331  110.397 116.474 1.00 31.56  ? 193 LYS D CE  1 
ATOM   2548 N  NZ  . LYS B 2 193 ? 93.338  111.713 117.169 1.00 31.56  ? 193 LYS D NZ  1 
ATOM   2549 N  N   . ARG B 2 194 ? 94.431  104.523 120.004 1.00 35.22  ? 194 ARG D N   1 
ATOM   2550 C  CA  . ARG B 2 194 ? 94.052  103.475 120.949 1.00 35.22  ? 194 ARG D CA  1 
ATOM   2551 C  C   . ARG B 2 194 ? 95.272  103.072 121.782 1.00 35.22  ? 194 ARG D C   1 
ATOM   2552 O  O   . ARG B 2 194 ? 95.584  101.894 121.952 1.00 35.22  ? 194 ARG D O   1 
ATOM   2553 C  CB  . ARG B 2 194 ? 93.453  102.281 120.209 1.00 35.22  ? 194 ARG D CB  1 
ATOM   2554 C  CG  . ARG B 2 194 ? 92.447  101.485 121.020 1.00 35.22  ? 194 ARG D CG  1 
ATOM   2555 C  CD  . ARG B 2 194 ? 91.723  100.464 120.159 1.00 35.22  ? 194 ARG D CD  1 
ATOM   2556 N  NE  . ARG B 2 194 ? 90.727  101.078 119.291 1.00 35.22  ? 194 ARG D NE  1 
ATOM   2557 C  CZ  . ARG B 2 194 ? 90.798  101.101 117.968 1.00 35.22  ? 194 ARG D CZ  1 
ATOM   2558 N  NH1 . ARG B 2 194 ? 91.812  100.551 117.321 1.00 35.22  ? 194 ARG D NH1 1 
ATOM   2559 N  NH2 . ARG B 2 194 ? 89.828  101.690 117.275 1.00 35.22  ? 194 ARG D NH2 1 
ATOM   2560 N  N   . GLY B 2 195 ? 95.974  104.075 122.301 1.00 36.30  ? 195 GLY D N   1 
ATOM   2561 C  CA  . GLY B 2 195 ? 97.198  103.857 123.048 1.00 36.30  ? 195 GLY D CA  1 
ATOM   2562 C  C   . GLY B 2 195 ? 97.044  103.141 124.375 1.00 36.30  ? 195 GLY D C   1 
ATOM   2563 O  O   . GLY B 2 195 ? 97.867  102.288 124.718 1.00 36.30  ? 195 GLY D O   1 
ATOM   2564 N  N   . LEU B 2 196 ? 96.002  103.484 125.137 1.00 36.47  ? 196 LEU D N   1 
ATOM   2565 C  CA  . LEU B 2 196 ? 95.831  102.903 126.466 1.00 36.47  ? 196 LEU D CA  1 
ATOM   2566 C  C   . LEU B 2 196 ? 95.621  101.395 126.394 1.00 36.47  ? 196 LEU D C   1 
ATOM   2567 O  O   . LEU B 2 196 ? 96.137  100.645 127.234 1.00 36.47  ? 196 LEU D O   1 
ATOM   2568 C  CB  . LEU B 2 196 ? 94.658  103.572 127.182 1.00 36.47  ? 196 LEU D CB  1 
ATOM   2569 C  CG  . LEU B 2 196 ? 94.359  103.085 128.601 1.00 36.47  ? 196 LEU D CG  1 
ATOM   2570 C  CD1 . LEU B 2 196 ? 95.465  103.498 129.555 1.00 36.47  ? 196 LEU D CD1 1 
ATOM   2571 C  CD2 . LEU B 2 196 ? 93.014  103.608 129.076 1.00 36.47  ? 196 LEU D CD2 1 
ATOM   2572 N  N   . GLU B 2 197 ? 94.861  100.934 125.399 1.00 44.42  ? 197 GLU D N   1 
ATOM   2573 C  CA  . GLU B 2 197 ? 94.576  99.509  125.276 1.00 44.42  ? 197 GLU D CA  1 
ATOM   2574 C  C   . GLU B 2 197 ? 95.848  98.702  125.051 1.00 44.42  ? 197 GLU D C   1 
ATOM   2575 O  O   . GLU B 2 197 ? 96.001  97.614  125.615 1.00 44.42  ? 197 GLU D O   1 
ATOM   2576 C  CB  . GLU B 2 197 ? 93.580  99.272  124.143 1.00 44.42  ? 197 GLU D CB  1 
ATOM   2577 C  CG  . GLU B 2 197 ? 92.136  99.580  124.506 1.00 44.42  ? 197 GLU D CG  1 
ATOM   2578 C  CD  . GLU B 2 197 ? 91.852  101.067 124.601 1.00 44.42  ? 197 GLU D CD  1 
ATOM   2579 O  OE1 . GLU B 2 197 ? 92.703  101.869 124.167 1.00 44.42  ? 197 GLU D OE1 1 
ATOM   2580 O  OE2 . GLU B 2 197 ? 90.773  101.433 125.112 1.00 44.42  ? 197 GLU D OE2 1 
ATOM   2581 N  N   . VAL B 2 198 ? 96.768  99.215  124.230 1.00 30.17  ? 198 VAL D N   1 
ATOM   2582 C  CA  . VAL B 2 198 ? 98.016  98.500  123.976 1.00 30.17  ? 198 VAL D CA  1 
ATOM   2583 C  C   . VAL B 2 198 ? 98.817  98.352  125.261 1.00 30.17  ? 198 VAL D C   1 
ATOM   2584 O  O   . VAL B 2 198 ? 99.341  97.272  125.563 1.00 30.17  ? 198 VAL D O   1 
ATOM   2585 C  CB  . VAL B 2 198 ? 98.832  99.218  122.886 1.00 30.17  ? 198 VAL D CB  1 
ATOM   2586 C  CG1 . VAL B 2 198 ? 100.169 98.528  122.688 1.00 30.17  ? 198 VAL D CG1 1 
ATOM   2587 C  CG2 . VAL B 2 198 ? 98.054  99.260  121.586 1.00 30.17  ? 198 VAL D CG2 1 
ATOM   2588 N  N   . LEU B 2 199 ? 98.925  99.432  126.037 1.00 29.83  ? 199 LEU D N   1 
ATOM   2589 C  CA  . LEU B 2 199 ? 99.673  99.378  127.288 1.00 29.83  ? 199 LEU D CA  1 
ATOM   2590 C  C   . LEU B 2 199 ? 99.038  98.396  128.265 1.00 29.83  ? 199 LEU D C   1 
ATOM   2591 O  O   . LEU B 2 199 ? 99.734  97.584  128.889 1.00 29.83  ? 199 LEU D O   1 
ATOM   2592 C  CB  . LEU B 2 199 ? 99.755  100.775 127.903 1.00 29.83  ? 199 LEU D CB  1 
ATOM   2593 C  CG  . LEU B 2 199 ? 100.578 100.920 129.181 1.00 29.83  ? 199 LEU D CG  1 
ATOM   2594 C  CD1 . LEU B 2 199 ? 102.053 100.706 128.895 1.00 29.83  ? 199 LEU D CD1 1 
ATOM   2595 C  CD2 . LEU B 2 199 ? 100.343 102.282 129.809 1.00 29.83  ? 199 LEU D CD2 1 
ATOM   2596 N  N   . LEU B 2 200 ? 97.711  98.452  128.405 1.00 34.85  ? 200 LEU D N   1 
ATOM   2597 C  CA  . LEU B 2 200 ? 97.034  97.548  129.328 1.00 34.85  ? 200 LEU D CA  1 
ATOM   2598 C  C   . LEU B 2 200 ? 97.201  96.095  128.904 1.00 34.85  ? 200 LEU D C   1 
ATOM   2599 O  O   . LEU B 2 200 ? 97.462  95.223  129.740 1.00 34.85  ? 200 LEU D O   1 
ATOM   2600 C  CB  . LEU B 2 200 ? 95.553  97.910  129.431 1.00 34.85  ? 200 LEU D CB  1 
ATOM   2601 C  CG  . LEU B 2 200 ? 95.229  99.105  130.327 1.00 34.85  ? 200 LEU D CG  1 
ATOM   2602 C  CD1 . LEU B 2 200 ? 93.741  99.400  130.309 1.00 34.85  ? 200 LEU D CD1 1 
ATOM   2603 C  CD2 . LEU B 2 200 ? 95.708  98.845  131.742 1.00 34.85  ? 200 LEU D CD2 1 
ATOM   2604 N  N   . LEU B 2 201 ? 97.062  95.816  127.606 1.00 30.34  ? 201 LEU D N   1 
ATOM   2605 C  CA  . LEU B 2 201 ? 97.207  94.449  127.120 1.00 30.34  ? 201 LEU D CA  1 
ATOM   2606 C  C   . LEU B 2 201 ? 98.629  93.940  127.312 1.00 30.34  ? 201 LEU D C   1 
ATOM   2607 O  O   . LEU B 2 201 ? 98.831  92.785  127.702 1.00 30.34  ? 201 LEU D O   1 
ATOM   2608 C  CB  . LEU B 2 201 ? 96.800  94.375  125.649 1.00 30.34  ? 201 LEU D CB  1 
ATOM   2609 C  CG  . LEU B 2 201 ? 96.704  92.984  125.027 1.00 30.34  ? 201 LEU D CG  1 
ATOM   2610 C  CD1 . LEU B 2 201 ? 95.835  92.080  125.880 1.00 30.34  ? 201 LEU D CD1 1 
ATOM   2611 C  CD2 . LEU B 2 201 ? 96.156  93.076  123.615 1.00 30.34  ? 201 LEU D CD2 1 
ATOM   2612 N  N   . LEU B 2 202 ? 99.629  94.786  127.047 1.00 30.29  ? 202 LEU D N   1 
ATOM   2613 C  CA  . LEU B 2 202 ? 101.013 94.368  127.238 1.00 30.29  ? 202 LEU D CA  1 
ATOM   2614 C  C   . LEU B 2 202 ? 101.308 94.085  128.705 1.00 30.29  ? 202 LEU D C   1 
ATOM   2615 O  O   . LEU B 2 202 ? 101.967 93.090  129.030 1.00 30.29  ? 202 LEU D O   1 
ATOM   2616 C  CB  . LEU B 2 202 ? 101.962 95.434  126.696 1.00 30.29  ? 202 LEU D CB  1 
ATOM   2617 C  CG  . LEU B 2 202 ? 102.183 95.412  125.184 1.00 30.29  ? 202 LEU D CG  1 
ATOM   2618 C  CD1 . LEU B 2 202 ? 103.002 96.611  124.743 1.00 30.29  ? 202 LEU D CD1 1 
ATOM   2619 C  CD2 . LEU B 2 202 ? 102.856 94.121  124.770 1.00 30.29  ? 202 LEU D CD2 1 
ATOM   2620 N  N   . LEU B 2 203 ? 100.826 94.944  129.607 1.00 30.42  ? 203 LEU D N   1 
ATOM   2621 C  CA  . LEU B 2 203 ? 101.050 94.707  131.029 1.00 30.42  ? 203 LEU D CA  1 
ATOM   2622 C  C   . LEU B 2 203 ? 100.343 93.441  131.496 1.00 30.42  ? 203 LEU D C   1 
ATOM   2623 O  O   . LEU B 2 203 ? 100.892 92.674  132.296 1.00 30.42  ? 203 LEU D O   1 
ATOM   2624 C  CB  . LEU B 2 203 ? 100.593 95.917  131.843 1.00 30.42  ? 203 LEU D CB  1 
ATOM   2625 C  CG  . LEU B 2 203 ? 101.434 97.179  131.653 1.00 30.42  ? 203 LEU D CG  1 
ATOM   2626 C  CD1 . LEU B 2 203 ? 100.972 98.279  132.590 1.00 30.42  ? 203 LEU D CD1 1 
ATOM   2627 C  CD2 . LEU B 2 203 ? 102.905 96.876  131.862 1.00 30.42  ? 203 LEU D CD2 1 
ATOM   2628 N  N   . SER B 2 204 ? 99.123  93.201  131.007 1.00 31.70  ? 204 SER D N   1 
ATOM   2629 C  CA  . SER B 2 204 ? 98.412  91.980  131.371 1.00 31.70  ? 204 SER D CA  1 
ATOM   2630 C  C   . SER B 2 204 ? 99.145  90.744  130.869 1.00 31.70  ? 204 SER D C   1 
ATOM   2631 O  O   . SER B 2 204 ? 99.236  89.736  131.579 1.00 31.70  ? 204 SER D O   1 
ATOM   2632 C  CB  . SER B 2 204 ? 96.988  92.021  130.821 1.00 31.70  ? 204 SER D CB  1 
ATOM   2633 O  OG  . SER B 2 204 ? 96.326  93.206  131.226 1.00 31.70  ? 204 SER D OG  1 
ATOM   2634 N  N   . LEU B 2 205 ? 99.671  90.800  129.642 1.00 31.26  ? 205 LEU D N   1 
ATOM   2635 C  CA  . LEU B 2 205 ? 100.425 89.670  129.109 1.00 31.26  ? 205 LEU D CA  1 
ATOM   2636 C  C   . LEU B 2 205 ? 101.697 89.431  129.910 1.00 31.26  ? 205 LEU D C   1 
ATOM   2637 O  O   . LEU B 2 205 ? 102.084 88.281  130.146 1.00 31.26  ? 205 LEU D O   1 
ATOM   2638 C  CB  . LEU B 2 205 ? 100.754 89.902  127.635 1.00 31.26  ? 205 LEU D CB  1 
ATOM   2639 C  CG  . LEU B 2 205 ? 99.661  89.521  126.638 1.00 31.26  ? 205 LEU D CG  1 
ATOM   2640 C  CD1 . LEU B 2 205 ? 100.031 89.969  125.236 1.00 31.26  ? 205 LEU D CD1 1 
ATOM   2641 C  CD2 . LEU B 2 205 ? 99.418  88.024  126.676 1.00 31.26  ? 205 LEU D CD2 1 
ATOM   2642 N  N   . TYR B 2 206 ? 102.370 90.506  130.325 1.00 29.74  ? 206 TYR D N   1 
ATOM   2643 C  CA  . TYR B 2 206 ? 103.556 90.352  131.161 1.00 29.74  ? 206 TYR D CA  1 
ATOM   2644 C  C   . TYR B 2 206 ? 103.204 89.717  132.500 1.00 29.74  ? 206 TYR D C   1 
ATOM   2645 O  O   . TYR B 2 206 ? 103.923 88.841  132.994 1.00 29.74  ? 206 TYR D O   1 
ATOM   2646 C  CB  . TYR B 2 206 ? 104.234 91.705  131.374 1.00 29.74  ? 206 TYR D CB  1 
ATOM   2647 C  CG  . TYR B 2 206 ? 105.317 91.663  132.425 1.00 29.74  ? 206 TYR D CG  1 
ATOM   2648 C  CD1 . TYR B 2 206 ? 106.484 90.943  132.217 1.00 29.74  ? 206 TYR D CD1 1 
ATOM   2649 C  CD2 . TYR B 2 206 ? 105.167 92.332  133.630 1.00 29.74  ? 206 TYR D CD2 1 
ATOM   2650 C  CE1 . TYR B 2 206 ? 107.474 90.897  133.175 1.00 29.74  ? 206 TYR D CE1 1 
ATOM   2651 C  CE2 . TYR B 2 206 ? 106.152 92.291  134.594 1.00 29.74  ? 206 TYR D CE2 1 
ATOM   2652 C  CZ  . TYR B 2 206 ? 107.303 91.572  134.361 1.00 29.74  ? 206 TYR D CZ  1 
ATOM   2653 O  OH  . TYR B 2 206 ? 108.288 91.527  135.319 1.00 29.74  ? 206 TYR D OH  1 
ATOM   2654 N  N   . LEU B 2 207 ? 102.099 90.157  133.109 1.00 34.92  ? 207 LEU D N   1 
ATOM   2655 C  CA  . LEU B 2 207 ? 101.696 89.609  134.400 1.00 34.92  ? 207 LEU D CA  1 
ATOM   2656 C  C   . LEU B 2 207 ? 101.316 88.137  134.290 1.00 34.92  ? 207 LEU D C   1 
ATOM   2657 O  O   . LEU B 2 207 ? 101.685 87.329  135.150 1.00 34.92  ? 207 LEU D O   1 
ATOM   2658 C  CB  . LEU B 2 207 ? 100.536 90.420  134.975 1.00 34.92  ? 207 LEU D CB  1 
ATOM   2659 C  CG  . LEU B 2 207 ? 100.913 91.786  135.545 1.00 34.92  ? 207 LEU D CG  1 
ATOM   2660 C  CD1 . LEU B 2 207 ? 99.673  92.539  135.989 1.00 34.92  ? 207 LEU D CD1 1 
ATOM   2661 C  CD2 . LEU B 2 207 ? 101.888 91.624  136.694 1.00 34.92  ? 207 LEU D CD2 1 
ATOM   2662 N  N   . ALA B 2 208 ? 100.577 87.770  133.241 1.00 35.70  ? 208 ALA D N   1 
ATOM   2663 C  CA  . ALA B 2 208 ? 100.170 86.378  133.076 1.00 35.70  ? 208 ALA D CA  1 
ATOM   2664 C  C   . ALA B 2 208 ? 101.363 85.485  132.763 1.00 35.70  ? 208 ALA D C   1 
ATOM   2665 O  O   . ALA B 2 208 ? 101.400 84.320  133.175 1.00 35.70  ? 208 ALA D O   1 
ATOM   2666 C  CB  . ALA B 2 208 ? 99.113  86.267  131.979 1.00 35.70  ? 208 ALA D CB  1 
ATOM   2667 N  N   . PHE B 2 209 ? 102.345 86.011  132.035 1.00 32.62  ? 209 PHE D N   1 
ATOM   2668 C  CA  . PHE B 2 209 ? 103.541 85.261  131.650 1.00 32.62  ? 209 PHE D CA  1 
ATOM   2669 C  C   . PHE B 2 209 ? 104.784 86.044  132.053 1.00 32.62  ? 209 PHE D C   1 
ATOM   2670 O  O   . PHE B 2 209 ? 105.352 86.794  131.254 1.00 32.62  ? 209 PHE D O   1 
ATOM   2671 C  CB  . PHE B 2 209 ? 103.534 84.972  130.151 1.00 32.62  ? 209 PHE D CB  1 
ATOM   2672 C  CG  . PHE B 2 209 ? 102.216 84.472  129.638 1.00 32.62  ? 209 PHE D CG  1 
ATOM   2673 C  CD1 . PHE B 2 209 ? 101.816 83.168  129.874 1.00 32.62  ? 209 PHE D CD1 1 
ATOM   2674 C  CD2 . PHE B 2 209 ? 101.374 85.307  128.925 1.00 32.62  ? 209 PHE D CD2 1 
ATOM   2675 C  CE1 . PHE B 2 209 ? 100.603 82.706  129.403 1.00 32.62  ? 209 PHE D CE1 1 
ATOM   2676 C  CE2 . PHE B 2 209 ? 100.159 84.851  128.452 1.00 32.62  ? 209 PHE D CE2 1 
ATOM   2677 C  CZ  . PHE B 2 209 ? 99.774  83.549  128.691 1.00 32.62  ? 209 PHE D CZ  1 
ATOM   2678 N  N   . PRO B 2 210 ? 105.237 85.894  133.300 1.00 36.06  ? 210 PRO D N   1 
ATOM   2679 C  CA  . PRO B 2 210 ? 106.381 86.693  133.761 1.00 36.06  ? 210 PRO D CA  1 
ATOM   2680 C  C   . PRO B 2 210 ? 107.725 86.153  133.310 1.00 36.06  ? 210 PRO D C   1 
ATOM   2681 O  O   . PRO B 2 210 ? 108.715 86.892  133.360 1.00 36.06  ? 210 PRO D O   1 
ATOM   2682 C  CB  . PRO B 2 210 ? 106.246 86.652  135.292 1.00 36.06  ? 210 PRO D CB  1 
ATOM   2683 C  CG  . PRO B 2 210 ? 105.167 85.606  135.593 1.00 36.06  ? 210 PRO D CG  1 
ATOM   2684 C  CD  . PRO B 2 210 ? 104.825 84.911  134.312 1.00 36.06  ? 210 PRO D CD  1 
ATOM   2685 N  N   . ASN B 2 211 ? 107.796 84.897  132.875 1.00 39.78  ? 211 ASN D N   1 
ATOM   2686 C  CA  . ASN B 2 211 ? 109.055 84.320  132.425 1.00 39.78  ? 211 ASN D CA  1 
ATOM   2687 C  C   . ASN B 2 211 ? 109.201 84.316  130.910 1.00 39.78  ? 211 ASN D C   1 
ATOM   2688 O  O   . ASN B 2 211 ? 110.165 83.733  130.402 1.00 39.78  ? 211 ASN D O   1 
ATOM   2689 C  CB  . ASN B 2 211 ? 109.196 82.890  132.953 1.00 39.78  ? 211 ASN D CB  1 
ATOM   2690 C  CG  . ASN B 2 211 ? 109.241 82.829  134.466 1.00 39.78  ? 211 ASN D CG  1 
ATOM   2691 O  OD1 . ASN B 2 211 ? 110.163 83.350  135.093 1.00 39.78  ? 211 ASN D OD1 1 
ATOM   2692 N  ND2 . ASN B 2 211 ? 108.240 82.190  135.063 1.00 39.78  ? 211 ASN D ND2 1 
ATOM   2693 N  N   . ALA B 2 212 ? 108.281 84.943  130.178 1.00 27.20  ? 212 ALA D N   1 
ATOM   2694 C  CA  . ALA B 2 212 ? 108.321 84.879  128.724 1.00 27.20  ? 212 ALA D CA  1 
ATOM   2695 C  C   . ALA B 2 212 ? 108.027 86.191  128.015 1.00 27.20  ? 212 ALA D C   1 
ATOM   2696 O  O   . ALA B 2 212 ? 107.989 86.192  126.782 1.00 27.20  ? 212 ALA D O   1 
ATOM   2697 C  CB  . ALA B 2 212 ? 107.336 83.818  128.216 1.00 27.20  ? 212 ALA D CB  1 
ATOM   2698 N  N   . VAL B 2 213 ? 107.812 87.296  128.721 1.00 24.13  ? 213 VAL D N   1 
ATOM   2699 C  CA  . VAL B 2 213 ? 107.593 88.597  128.099 1.00 24.13  ? 213 VAL D CA  1 
ATOM   2700 C  C   . VAL B 2 213 ? 108.567 89.590  128.711 1.00 24.13  ? 213 VAL D C   1 
ATOM   2701 O  O   . VAL B 2 213 ? 108.633 89.731  129.938 1.00 24.13  ? 213 VAL D O   1 
ATOM   2702 C  CB  . VAL B 2 213 ? 106.140 89.072  128.270 1.00 24.13  ? 213 VAL D CB  1 
ATOM   2703 C  CG1 . VAL B 2 213 ? 105.975 90.472  127.711 1.00 24.13  ? 213 VAL D CG1 1 
ATOM   2704 C  CG2 . VAL B 2 213 ? 105.190 88.113  127.581 1.00 24.13  ? 213 VAL D CG2 1 
ATOM   2705 N  N   . PHE B 2 214 ? 109.321 90.278  127.859 1.00 25.76  ? 214 PHE D N   1 
ATOM   2706 C  CA  . PHE B 2 214 ? 110.285 91.279  128.286 1.00 25.76  ? 214 PHE D CA  1 
ATOM   2707 C  C   . PHE B 2 214 ? 109.961 92.609  127.623 1.00 25.76  ? 214 PHE D C   1 
ATOM   2708 O  O   . PHE B 2 214 ? 109.622 92.655  126.437 1.00 25.76  ? 214 PHE D O   1 
ATOM   2709 C  CB  . PHE B 2 214 ? 111.713 90.854  127.942 1.00 25.76  ? 214 PHE D CB  1 
ATOM   2710 C  CG  . PHE B 2 214 ? 112.091 89.510  128.490 1.00 25.76  ? 214 PHE D CG  1 
ATOM   2711 C  CD1 . PHE B 2 214 ? 112.474 89.370  129.812 1.00 25.76  ? 214 PHE D CD1 1 
ATOM   2712 C  CD2 . PHE B 2 214 ? 112.064 88.386  127.684 1.00 25.76  ? 214 PHE D CD2 1 
ATOM   2713 C  CE1 . PHE B 2 214 ? 112.822 88.134  130.320 1.00 25.76  ? 214 PHE D CE1 1 
ATOM   2714 C  CE2 . PHE B 2 214 ? 112.412 87.149  128.186 1.00 25.76  ? 214 PHE D CE2 1 
ATOM   2715 C  CZ  . PHE B 2 214 ? 112.792 87.023  129.506 1.00 25.76  ? 214 PHE D CZ  1 
ATOM   2716 N  N   . LEU B 2 215 ? 110.064 93.686  128.394 1.00 33.70  ? 215 LEU D N   1 
ATOM   2717 C  CA  . LEU B 2 215 ? 109.750 95.025  127.922 1.00 33.70  ? 215 LEU D CA  1 
ATOM   2718 C  C   . LEU B 2 215 ? 110.998 95.893  127.976 1.00 33.70  ? 215 LEU D C   1 
ATOM   2719 O  O   . LEU B 2 215 ? 111.850 95.718  128.852 1.00 33.70  ? 215 LEU D O   1 
ATOM   2720 C  CB  . LEU B 2 215 ? 108.637 95.659  128.759 1.00 33.70  ? 215 LEU D CB  1 
ATOM   2721 C  CG  . LEU B 2 215 ? 107.403 94.795  129.010 1.00 33.70  ? 215 LEU D CG  1 
ATOM   2722 C  CD1 . LEU B 2 215 ? 106.378 95.553  129.833 1.00 33.70  ? 215 LEU D CD1 1 
ATOM   2723 C  CD2 . LEU B 2 215 ? 106.801 94.337  127.698 1.00 33.70  ? 215 LEU D CD2 1 
ATOM   2724 N  N   . ASN B 2 216 ? 111.102 96.825  127.034 1.00 51.63  ? 216 ASN D N   1 
ATOM   2725 C  CA  . ASN B 2 216 ? 112.206 97.769  126.972 1.00 51.63  ? 216 ASN D CA  1 
ATOM   2726 C  C   . ASN B 2 216 ? 111.655 99.184  126.912 1.00 51.63  ? 216 ASN D C   1 
ATOM   2727 O  O   . ASN B 2 216 ? 110.668 99.446  126.220 1.00 51.63  ? 216 ASN D O   1 
ATOM   2728 C  CB  . ASN B 2 216 ? 113.099 97.504  125.759 1.00 51.63  ? 216 ASN D CB  1 
ATOM   2729 C  CG  . ASN B 2 216 ? 113.752 96.141  125.806 1.00 51.63  ? 216 ASN D CG  1 
ATOM   2730 O  OD1 . ASN B 2 216 ? 114.003 95.597  126.880 1.00 51.63  ? 216 ASN D OD1 1 
ATOM   2731 N  ND2 . ASN B 2 216 ? 114.034 95.581  124.638 1.00 51.63  ? 216 ASN D ND2 1 
ATOM   2732 N  N   . ARG B 2 217 ? 112.288 100.092 127.647 1.00 48.54  ? 217 ARG D N   1 
ATOM   2733 C  CA  . ARG B 2 217 ? 111.843 101.476 127.663 1.00 48.54  ? 217 ARG D CA  1 
ATOM   2734 C  C   . ARG B 2 217 ? 112.205 102.169 126.354 1.00 48.54  ? 217 ARG D C   1 
ATOM   2735 O  O   . ARG B 2 217 ? 113.236 101.887 125.739 1.00 48.54  ? 217 ARG D O   1 
ATOM   2736 C  CB  . ARG B 2 217 ? 112.464 102.220 128.843 1.00 48.54  ? 217 ARG D CB  1 
ATOM   2737 C  CG  . ARG B 2 217 ? 111.799 103.545 129.154 1.00 48.54  ? 217 ARG D CG  1 
ATOM   2738 C  CD  . ARG B 2 217 ? 112.415 104.191 130.377 1.00 48.54  ? 217 ARG D CD  1 
ATOM   2739 N  NE  . ARG B 2 217 ? 111.754 105.444 130.714 1.00 48.54  ? 217 ARG D NE  1 
ATOM   2740 C  CZ  . ARG B 2 217 ? 111.925 106.093 131.856 1.00 48.54  ? 217 ARG D CZ  1 
ATOM   2741 N  NH1 . ARG B 2 217 ? 112.732 105.633 132.797 1.00 48.54  ? 217 ARG D NH1 1 
ATOM   2742 N  NH2 . ARG B 2 217 ? 111.267 107.230 132.060 1.00 48.54  ? 217 ARG D NH2 1 
ATOM   2743 N  N   . GLY B 2 218 ? 111.338 103.089 125.929 1.00 31.40  ? 218 GLY D N   1 
ATOM   2744 C  CA  . GLY B 2 218 ? 111.536 103.811 124.690 1.00 31.40  ? 218 GLY D CA  1 
ATOM   2745 C  C   . GLY B 2 218 ? 111.573 105.308 124.924 1.00 31.40  ? 218 GLY D C   1 
ATOM   2746 O  O   . GLY B 2 218 ? 111.317 105.788 126.028 1.00 31.40  ? 218 GLY D O   1 
ATOM   2747 N  N   . ASN B 2 219 ? 111.898 106.038 123.856 1.00 31.80  ? 219 ASN D N   1 
ATOM   2748 C  CA  . ASN B 2 219 ? 111.976 107.490 123.951 1.00 31.80  ? 219 ASN D CA  1 
ATOM   2749 C  C   . ASN B 2 219 ? 110.611 108.127 124.154 1.00 31.80  ? 219 ASN D C   1 
ATOM   2750 O  O   . ASN B 2 219 ? 110.534 109.252 124.657 1.00 31.80  ? 219 ASN D O   1 
ATOM   2751 C  CB  . ASN B 2 219 ? 112.638 108.069 122.700 1.00 31.80  ? 219 ASN D CB  1 
ATOM   2752 C  CG  . ASN B 2 219 ? 111.881 107.736 121.431 1.00 31.80  ? 219 ASN D CG  1 
ATOM   2753 O  OD1 . ASN B 2 219 ? 111.791 106.577 121.033 1.00 31.80  ? 219 ASN D OD1 1 
ATOM   2754 N  ND2 . ASN B 2 219 ? 111.337 108.759 120.783 1.00 31.80  ? 219 ASN D ND2 1 
ATOM   2755 N  N   . HIS B 2 220 ? 109.537 107.441 123.778 1.00 29.61  ? 220 HIS D N   1 
ATOM   2756 C  CA  . HIS B 2 220 ? 108.187 107.945 123.981 1.00 29.61  ? 220 HIS D CA  1 
ATOM   2757 C  C   . HIS B 2 220 ? 107.592 107.508 125.311 1.00 29.61  ? 220 HIS D C   1 
ATOM   2758 O  O   . HIS B 2 220 ? 106.427 107.814 125.582 1.00 29.61  ? 220 HIS D O   1 
ATOM   2759 C  CB  . HIS B 2 220 ? 107.274 107.499 122.835 1.00 29.61  ? 220 HIS D CB  1 
ATOM   2760 C  CG  . HIS B 2 220 ? 107.260 108.444 121.674 1.00 29.61  ? 220 HIS D CG  1 
ATOM   2761 N  ND1 . HIS B 2 220 ? 106.197 109.278 121.407 1.00 29.61  ? 220 HIS D ND1 1 
ATOM   2762 C  CD2 . HIS B 2 220 ? 108.178 108.685 120.709 1.00 29.61  ? 220 HIS D CD2 1 
ATOM   2763 C  CE1 . HIS B 2 220 ? 106.461 109.993 120.328 1.00 29.61  ? 220 HIS D CE1 1 
ATOM   2764 N  NE2 . HIS B 2 220 ? 107.657 109.652 119.885 1.00 29.61  ? 220 HIS D NE2 1 
ATOM   2765 N  N   . GLU B 2 221 ? 108.356 106.797 126.139 1.00 36.69  ? 221 GLU D N   1 
ATOM   2766 C  CA  . GLU B 2 221 ? 107.924 106.442 127.489 1.00 36.69  ? 221 GLU D CA  1 
ATOM   2767 C  C   . GLU B 2 221 ? 108.290 107.567 128.461 1.00 36.69  ? 221 GLU D C   1 
ATOM   2768 O  O   . GLU B 2 221 ? 109.015 107.386 129.438 1.00 36.69  ? 221 GLU D O   1 
ATOM   2769 C  CB  . GLU B 2 221 ? 108.548 105.118 127.914 1.00 36.69  ? 221 GLU D CB  1 
ATOM   2770 C  CG  . GLU B 2 221 ? 108.041 103.847 127.210 1.00 36.69  ? 221 GLU D CG  1 
ATOM   2771 C  CD  . GLU B 2 221 ? 106.535 103.598 127.296 1.00 36.69  ? 221 GLU D CD  1 
ATOM   2772 O  OE1 . GLU B 2 221 ? 105.734 104.542 127.449 1.00 36.69  ? 221 GLU D OE1 1 
ATOM   2773 O  OE2 . GLU B 2 221 ? 106.148 102.416 127.215 1.00 36.69  ? 221 GLU D OE2 1 
ATOM   2774 N  N   . ASP B 2 222 ? 107.768 108.753 128.163 1.00 40.90  ? 222 ASP D N   1 
ATOM   2775 C  CA  . ASP B 2 222 ? 108.132 109.955 128.906 1.00 40.90  ? 222 ASP D CA  1 
ATOM   2776 C  C   . ASP B 2 222 ? 106.873 110.760 129.170 1.00 40.90  ? 222 ASP D C   1 
ATOM   2777 O  O   . ASP B 2 222 ? 106.024 110.884 128.283 1.00 40.90  ? 222 ASP D O   1 
ATOM   2778 C  CB  . ASP B 2 222 ? 109.149 110.781 128.124 1.00 40.90  ? 222 ASP D CB  1 
ATOM   2779 C  CG  . ASP B 2 222 ? 110.065 111.577 129.023 1.00 40.90  ? 222 ASP D CG  1 
ATOM   2780 O  OD1 . ASP B 2 222 ? 109.632 111.949 130.132 1.00 40.90  ? 222 ASP D OD1 1 
ATOM   2781 O  OD2 . ASP B 2 222 ? 111.218 111.834 128.618 1.00 40.90  ? 222 ASP D OD2 1 
ATOM   2782 N  N   . SER B 2 223 ? 106.751 111.304 130.382 1.00 38.43  ? 223 SER D N   1 
ATOM   2783 C  CA  . SER B 2 223 ? 105.591 112.126 130.704 1.00 38.43  ? 223 SER D CA  1 
ATOM   2784 C  C   . SER B 2 223 ? 105.570 113.410 129.887 1.00 38.43  ? 223 SER D C   1 
ATOM   2785 O  O   . SER B 2 223 ? 104.493 113.931 129.577 1.00 38.43  ? 223 SER D O   1 
ATOM   2786 C  CB  . SER B 2 223 ? 105.572 112.448 132.198 1.00 38.43  ? 223 SER D CB  1 
ATOM   2787 O  OG  . SER B 2 223 ? 104.406 113.173 132.545 1.00 38.43  ? 223 SER D OG  1 
ATOM   2788 N  N   . VAL B 2 224 ? 106.744 113.937 129.534 1.00 37.94  ? 224 VAL D N   1 
ATOM   2789 C  CA  . VAL B 2 224 ? 106.801 115.162 128.744 1.00 37.94  ? 224 VAL D CA  1 
ATOM   2790 C  C   . VAL B 2 224 ? 106.326 114.916 127.319 1.00 37.94  ? 224 VAL D C   1 
ATOM   2791 O  O   . VAL B 2 224 ? 105.572 115.722 126.760 1.00 37.94  ? 224 VAL D O   1 
ATOM   2792 C  CB  . VAL B 2 224 ? 108.226 115.742 128.766 1.00 37.94  ? 224 VAL D CB  1 
ATOM   2793 C  CG1 . VAL B 2 224 ? 108.277 117.050 127.996 1.00 37.94  ? 224 VAL D CG1 1 
ATOM   2794 C  CG2 . VAL B 2 224 ? 108.694 115.937 130.196 1.00 37.94  ? 224 VAL D CG2 1 
ATOM   2795 N  N   . MET B 2 225 ? 106.750 113.809 126.707 1.00 38.73  ? 225 MET D N   1 
ATOM   2796 C  CA  . MET B 2 225 ? 106.399 113.539 125.317 1.00 38.73  ? 225 MET D CA  1 
ATOM   2797 C  C   . MET B 2 225 ? 104.924 113.194 125.159 1.00 38.73  ? 225 MET D C   1 
ATOM   2798 O  O   . MET B 2 225 ? 104.326 113.482 124.117 1.00 38.73  ? 225 MET D O   1 
ATOM   2799 C  CB  . MET B 2 225 ? 107.270 112.410 124.768 1.00 38.73  ? 225 MET D CB  1 
ATOM   2800 C  CG  . MET B 2 225 ? 108.655 112.852 124.336 1.00 38.73  ? 225 MET D CG  1 
ATOM   2801 S  SD  . MET B 2 225 ? 108.616 113.922 122.889 1.00 38.73  ? 225 MET D SD  1 
ATOM   2802 C  CE  . MET B 2 225 ? 109.385 112.863 121.670 1.00 38.73  ? 225 MET D CE  1 
ATOM   2803 N  N   . ASN B 2 226 ? 104.322 112.575 126.178 1.00 40.26  ? 226 ASN D N   1 
ATOM   2804 C  CA  . ASN B 2 226 ? 102.922 112.176 126.080 1.00 40.26  ? 226 ASN D CA  1 
ATOM   2805 C  C   . ASN B 2 226 ? 101.994 113.378 125.963 1.00 40.26  ? 226 ASN D C   1 
ATOM   2806 O  O   . ASN B 2 226 ? 101.003 113.325 125.227 1.00 40.26  ? 226 ASN D O   1 
ATOM   2807 C  CB  . ASN B 2 226 ? 102.532 111.328 127.290 1.00 40.26  ? 226 ASN D CB  1 
ATOM   2808 C  CG  . ASN B 2 226 ? 103.014 109.900 127.177 1.00 40.26  ? 226 ASN D CG  1 
ATOM   2809 O  OD1 . ASN B 2 226 ? 103.485 109.476 126.124 1.00 40.26  ? 226 ASN D OD1 1 
ATOM   2810 N  ND2 . ASN B 2 226 ? 102.898 109.149 128.264 1.00 40.26  ? 226 ASN D ND2 1 
ATOM   2811 N  N   . ALA B 2 227 ? 102.293 114.464 126.679 1.00 40.51  ? 227 ALA D N   1 
ATOM   2812 C  CA  . ALA B 2 227 ? 101.407 115.623 126.667 1.00 40.51  ? 227 ALA D CA  1 
ATOM   2813 C  C   . ALA B 2 227 ? 101.423 116.342 125.325 1.00 40.51  ? 227 ALA D C   1 
ATOM   2814 O  O   . ALA B 2 227 ? 100.540 117.164 125.056 1.00 40.51  ? 227 ALA D O   1 
ATOM   2815 C  CB  . ALA B 2 227 ? 101.794 116.589 127.785 1.00 40.51  ? 227 ALA D CB  1 
ATOM   2816 N  N   . ARG B 2 228 ? 102.406 116.052 124.475 1.00 49.62  ? 228 ARG D N   1 
ATOM   2817 C  CA  . ARG B 2 228 ? 102.544 116.758 123.208 1.00 49.62  ? 228 ARG D CA  1 
ATOM   2818 C  C   . ARG B 2 228 ? 102.010 115.965 122.024 1.00 49.62  ? 228 ARG D C   1 
ATOM   2819 O  O   . ARG B 2 228 ? 101.809 116.539 120.948 1.00 49.62  ? 228 ARG D O   1 
ATOM   2820 C  CB  . ARG B 2 228 ? 104.014 117.112 122.967 1.00 49.62  ? 228 ARG D CB  1 
ATOM   2821 C  CG  . ARG B 2 228 ? 104.238 118.297 122.042 1.00 49.62  ? 228 ARG D CG  1 
ATOM   2822 C  CD  . ARG B 2 228 ? 104.829 117.857 120.713 1.00 49.62  ? 228 ARG D CD  1 
ATOM   2823 N  NE  . ARG B 2 228 ? 104.958 118.968 119.777 1.00 49.62  ? 228 ARG D NE  1 
ATOM   2824 C  CZ  . ARG B 2 228 ? 104.007 119.356 118.938 1.00 49.62  ? 228 ARG D CZ  1 
ATOM   2825 N  NH1 . ARG B 2 228 ? 102.839 118.738 118.883 1.00 49.62  ? 228 ARG D NH1 1 
ATOM   2826 N  NH2 . ARG B 2 228 ? 104.235 120.389 118.133 1.00 49.62  ? 228 ARG D NH2 1 
ATOM   2827 N  N   . TYR B 2 229 ? 101.768 114.664 122.190 1.00 47.04  ? 229 TYR D N   1 
ATOM   2828 C  CA  . TYR B 2 229 ? 101.354 113.806 121.086 1.00 47.04  ? 229 TYR D CA  1 
ATOM   2829 C  C   . TYR B 2 229 ? 99.992  113.161 121.333 1.00 47.04  ? 229 TYR D C   1 
ATOM   2830 O  O   . TYR B 2 229 ? 99.655  112.152 120.710 1.00 47.04  ? 229 TYR D O   1 
ATOM   2831 C  CB  . TYR B 2 229 ? 102.417 112.745 120.805 1.00 47.04  ? 229 TYR D CB  1 
ATOM   2832 C  CG  . TYR B 2 229 ? 103.613 113.291 120.060 1.00 47.04  ? 229 TYR D CG  1 
ATOM   2833 C  CD1 . TYR B 2 229 ? 103.574 113.471 118.685 1.00 47.04  ? 229 TYR D CD1 1 
ATOM   2834 C  CD2 . TYR B 2 229 ? 104.775 113.639 120.733 1.00 47.04  ? 229 TYR D CD2 1 
ATOM   2835 C  CE1 . TYR B 2 229 ? 104.662 113.975 118.000 1.00 47.04  ? 229 TYR D CE1 1 
ATOM   2836 C  CE2 . TYR B 2 229 ? 105.869 114.144 120.056 1.00 47.04  ? 229 TYR D CE2 1 
ATOM   2837 C  CZ  . TYR B 2 229 ? 105.806 114.309 118.690 1.00 47.04  ? 229 TYR D CZ  1 
ATOM   2838 O  OH  . TYR B 2 229 ? 106.892 114.811 118.012 1.00 47.04  ? 229 TYR D OH  1 
ATOM   2839 N  N   . GLY B 2 230 ? 99.201  113.729 122.241 1.00 46.00  ? 230 GLY D N   1 
ATOM   2840 C  CA  . GLY B 2 230 ? 97.793  113.411 122.338 1.00 46.00  ? 230 GLY D CA  1 
ATOM   2841 C  C   . GLY B 2 230 ? 97.411  112.292 123.286 1.00 46.00  ? 230 GLY D C   1 
ATOM   2842 O  O   . GLY B 2 230 ? 96.211  112.043 123.460 1.00 46.00  ? 230 GLY D O   1 
ATOM   2843 N  N   . PHE B 2 231 ? 98.375  111.603 123.899 1.00 43.47  ? 231 PHE D N   1 
ATOM   2844 C  CA  . PHE B 2 231 ? 98.021  110.515 124.808 1.00 43.47  ? 231 PHE D CA  1 
ATOM   2845 C  C   . PHE B 2 231 ? 97.274  111.028 126.033 1.00 43.47  ? 231 PHE D C   1 
ATOM   2846 O  O   . PHE B 2 231 ? 96.258  110.447 126.437 1.00 43.47  ? 231 PHE D O   1 
ATOM   2847 C  CB  . PHE B 2 231 ? 99.272  109.751 125.235 1.00 43.47  ? 231 PHE D CB  1 
ATOM   2848 C  CG  . PHE B 2 231 ? 98.997  108.630 126.195 1.00 43.47  ? 231 PHE D CG  1 
ATOM   2849 C  CD1 . PHE B 2 231 ? 97.933  107.770 125.990 1.00 43.47  ? 231 PHE D CD1 1 
ATOM   2850 C  CD2 . PHE B 2 231 ? 99.803  108.437 127.303 1.00 43.47  ? 231 PHE D CD2 1 
ATOM   2851 C  CE1 . PHE B 2 231 ? 97.680  106.739 126.871 1.00 43.47  ? 231 PHE D CE1 1 
ATOM   2852 C  CE2 . PHE B 2 231 ? 99.552  107.408 128.187 1.00 43.47  ? 231 PHE D CE2 1 
ATOM   2853 C  CZ  . PHE B 2 231 ? 98.490  106.559 127.972 1.00 43.47  ? 231 PHE D CZ  1 
ATOM   2854 N  N   . ILE B 2 232 ? 97.762  112.113 126.639 1.00 47.34  ? 232 ILE D N   1 
ATOM   2855 C  CA  . ILE B 2 232 ? 97.112  112.652 127.829 1.00 47.34  ? 232 ILE D CA  1 
ATOM   2856 C  C   . ILE B 2 232 ? 95.704  113.125 127.495 1.00 47.34  ? 232 ILE D C   1 
ATOM   2857 O  O   . ILE B 2 232 ? 94.772  112.961 128.291 1.00 47.34  ? 232 ILE D O   1 
ATOM   2858 C  CB  . ILE B 2 232 ? 97.969  113.775 128.442 1.00 47.34  ? 232 ILE D CB  1 
ATOM   2859 C  CG1 . ILE B 2 232 ? 99.183  113.176 129.153 1.00 47.34  ? 232 ILE D CG1 1 
ATOM   2860 C  CG2 . ILE B 2 232 ? 97.152  114.619 129.406 1.00 47.34  ? 232 ILE D CG2 1 
ATOM   2861 C  CD1 . ILE B 2 232 ? 100.015 114.188 129.904 1.00 47.34  ? 232 ILE D CD1 1 
ATOM   2862 N  N   . ARG B 2 233 ? 95.524  113.705 126.306 1.00 56.20  ? 233 ARG D N   1 
ATOM   2863 C  CA  . ARG B 2 233 ? 94.188  114.104 125.875 1.00 56.20  ? 233 ARG D CA  1 
ATOM   2864 C  C   . ARG B 2 233 ? 93.262  112.899 125.772 1.00 56.20  ? 233 ARG D C   1 
ATOM   2865 O  O   . ARG B 2 233 ? 92.099  112.964 126.186 1.00 56.20  ? 233 ARG D O   1 
ATOM   2866 C  CB  . ARG B 2 233 ? 94.267  114.838 124.537 1.00 56.20  ? 233 ARG D CB  1 
ATOM   2867 C  CG  . ARG B 2 233 ? 95.596  115.530 124.286 1.00 56.20  ? 233 ARG D CG  1 
ATOM   2868 C  CD  . ARG B 2 233 ? 95.680  116.858 125.022 1.00 56.20  ? 233 ARG D CD  1 
ATOM   2869 N  NE  . ARG B 2 233 ? 94.504  117.686 124.785 1.00 56.20  ? 233 ARG D NE  1 
ATOM   2870 C  CZ  . ARG B 2 233 ? 94.307  118.414 123.695 1.00 56.20  ? 233 ARG D CZ  1 
ATOM   2871 N  NH1 . ARG B 2 233 ? 95.196  118.446 122.715 1.00 56.20  ? 233 ARG D NH1 1 
ATOM   2872 N  NH2 . ARG B 2 233 ? 93.191  119.130 123.584 1.00 56.20  ? 233 ARG D NH2 1 
ATOM   2873 N  N   . GLU B 2 234 ? 93.761  111.790 125.223 1.00 54.38  ? 234 GLU D N   1 
ATOM   2874 C  CA  . GLU B 2 234 ? 92.949  110.583 125.105 1.00 54.38  ? 234 GLU D CA  1 
ATOM   2875 C  C   . GLU B 2 234 ? 92.565  110.040 126.477 1.00 54.38  ? 234 GLU D C   1 
ATOM   2876 O  O   . GLU B 2 234 ? 91.414  109.649 126.706 1.00 54.38  ? 234 GLU D O   1 
ATOM   2877 C  CB  . GLU B 2 234 ? 93.703  109.526 124.297 1.00 54.38  ? 234 GLU D CB  1 
ATOM   2878 C  CG  . GLU B 2 234 ? 93.118  108.130 124.408 1.00 54.38  ? 234 GLU D CG  1 
ATOM   2879 C  CD  . GLU B 2 234 ? 94.163  107.048 124.241 1.00 54.38  ? 234 GLU D CD  1 
ATOM   2880 O  OE1 . GLU B 2 234 ? 95.034  107.195 123.359 1.00 54.38  ? 234 GLU D OE1 1 
ATOM   2881 O  OE2 . GLU B 2 234 ? 94.115  106.051 124.992 1.00 54.38  ? 234 GLU D OE2 1 
ATOM   2882 N  N   . VAL B 2 235 ? 93.522  110.010 127.408 1.00 49.66  ? 235 VAL D N   1 
ATOM   2883 C  CA  . VAL B 2 235 ? 93.224  109.515 128.750 1.00 49.66  ? 235 VAL D CA  1 
ATOM   2884 C  C   . VAL B 2 235 ? 92.197  110.408 129.432 1.00 49.66  ? 235 VAL D C   1 
ATOM   2885 O  O   . VAL B 2 235 ? 91.260  109.920 130.076 1.00 49.66  ? 235 VAL D O   1 
ATOM   2886 C  CB  . VAL B 2 235 ? 94.512  109.399 129.585 1.00 49.66  ? 235 VAL D CB  1 
ATOM   2887 C  CG1 . VAL B 2 235 ? 94.196  108.837 130.959 1.00 49.66  ? 235 VAL D CG1 1 
ATOM   2888 C  CG2 . VAL B 2 235 ? 95.515  108.515 128.882 1.00 49.66  ? 235 VAL D CG2 1 
ATOM   2889 N  N   . GLU B 2 236 ? 92.356  111.727 129.305 1.00 57.92  ? 236 GLU D N   1 
ATOM   2890 C  CA  . GLU B 2 236 ? 91.405  112.651 129.913 1.00 57.92  ? 236 GLU D CA  1 
ATOM   2891 C  C   . GLU B 2 236 ? 90.013  112.498 129.315 1.00 57.92  ? 236 GLU D C   1 
ATOM   2892 O  O   . GLU B 2 236 ? 89.017  112.541 130.046 1.00 57.92  ? 236 GLU D O   1 
ATOM   2893 C  CB  . GLU B 2 236 ? 91.898  114.089 129.755 1.00 57.92  ? 236 GLU D CB  1 
ATOM   2894 C  CG  . GLU B 2 236 ? 93.058  114.450 130.667 1.00 57.92  ? 236 GLU D CG  1 
ATOM   2895 C  CD  . GLU B 2 236 ? 93.736  115.744 130.263 1.00 57.92  ? 236 GLU D CD  1 
ATOM   2896 O  OE1 . GLU B 2 236 ? 93.386  116.293 129.198 1.00 57.92  ? 236 GLU D OE1 1 
ATOM   2897 O  OE2 . GLU B 2 236 ? 94.621  116.212 131.010 1.00 57.92  ? 236 GLU D OE2 1 
ATOM   2898 N  N   . SER B 2 237 ? 89.920  112.327 127.995 1.00 54.84  ? 237 SER D N   1 
ATOM   2899 C  CA  . SER B 2 237 ? 88.621  112.139 127.362 1.00 54.84  ? 237 SER D CA  1 
ATOM   2900 C  C   . SER B 2 237 ? 87.965  110.827 127.771 1.00 54.84  ? 237 SER D C   1 
ATOM   2901 O  O   . SER B 2 237 ? 86.753  110.795 128.009 1.00 54.84  ? 237 SER D O   1 
ATOM   2902 C  CB  . SER B 2 237 ? 88.762  112.198 125.841 1.00 54.84  ? 237 SER D CB  1 
ATOM   2903 O  OG  . SER B 2 237 ? 89.290  110.986 125.333 1.00 54.84  ? 237 SER D OG  1 
ATOM   2904 N  N   . LYS B 2 238 ? 88.736  109.741 127.859 1.00 55.96  ? 238 LYS D N   1 
ATOM   2905 C  CA  . LYS B 2 238 ? 88.147  108.444 128.175 1.00 55.96  ? 238 LYS D CA  1 
ATOM   2906 C  C   . LYS B 2 238 ? 87.723  108.350 129.636 1.00 55.96  ? 238 LYS D C   1 
ATOM   2907 O  O   . LYS B 2 238 ? 86.688  107.750 129.944 1.00 55.96  ? 238 LYS D O   1 
ATOM   2908 C  CB  . LYS B 2 238 ? 89.126  107.323 127.827 1.00 55.96  ? 238 LYS D CB  1 
ATOM   2909 C  CG  . LYS B 2 238 ? 89.176  106.998 126.342 1.00 55.96  ? 238 LYS D CG  1 
ATOM   2910 C  CD  . LYS B 2 238 ? 90.027  105.772 126.064 1.00 55.96  ? 238 LYS D CD  1 
ATOM   2911 C  CE  . LYS B 2 238 ? 89.996  105.409 124.588 1.00 55.96  ? 238 LYS D CE  1 
ATOM   2912 N  NZ  . LYS B 2 238 ? 90.942  104.308 124.263 1.00 55.96  ? 238 LYS D NZ  1 
ATOM   2913 N  N   . TYR B 2 239 ? 88.499  108.933 130.547 1.00 61.81  ? 239 TYR D N   1 
ATOM   2914 C  CA  . TYR B 2 239 ? 88.206  108.890 131.981 1.00 61.81  ? 239 TYR D CA  1 
ATOM   2915 C  C   . TYR B 2 239 ? 88.247  110.298 132.564 1.00 61.81  ? 239 TYR D C   1 
ATOM   2916 O  O   . TYR B 2 239 ? 89.188  110.665 133.273 1.00 61.81  ? 239 TYR D O   1 
ATOM   2917 C  CB  . TYR B 2 239 ? 89.188  107.972 132.706 1.00 61.81  ? 239 TYR D CB  1 
ATOM   2918 C  CG  . TYR B 2 239 ? 89.026  106.507 132.381 1.00 61.81  ? 239 TYR D CG  1 
ATOM   2919 C  CD1 . TYR B 2 239 ? 87.942  105.787 132.859 1.00 61.81  ? 239 TYR D CD1 1 
ATOM   2920 C  CD2 . TYR B 2 239 ? 89.962  105.842 131.602 1.00 61.81  ? 239 TYR D CD2 1 
ATOM   2921 C  CE1 . TYR B 2 239 ? 87.792  104.447 132.567 1.00 61.81  ? 239 TYR D CE1 1 
ATOM   2922 C  CE2 . TYR B 2 239 ? 89.820  104.503 131.305 1.00 61.81  ? 239 TYR D CE2 1 
ATOM   2923 C  CZ  . TYR B 2 239 ? 88.734  103.810 131.790 1.00 61.81  ? 239 TYR D CZ  1 
ATOM   2924 O  OH  . TYR B 2 239 ? 88.588  102.474 131.497 1.00 61.81  ? 239 TYR D OH  1 
ATOM   2925 N  N   . PRO B 2 240 ? 87.233  111.118 132.279 1.00 71.72  ? 240 PRO D N   1 
ATOM   2926 C  CA  . PRO B 2 240 ? 87.235  112.495 132.799 1.00 71.72  ? 240 PRO D CA  1 
ATOM   2927 C  C   . PRO B 2 240 ? 87.237  112.583 134.315 1.00 71.72  ? 240 PRO D C   1 
ATOM   2928 O  O   . PRO B 2 240 ? 87.826  113.522 134.864 1.00 71.72  ? 240 PRO D O   1 
ATOM   2929 C  CB  . PRO B 2 240 ? 85.953  113.094 132.206 1.00 71.72  ? 240 PRO D CB  1 
ATOM   2930 C  CG  . PRO B 2 240 ? 85.076  111.913 131.952 1.00 71.72  ? 240 PRO D CG  1 
ATOM   2931 C  CD  . PRO B 2 240 ? 86.006  110.818 131.523 1.00 71.72  ? 240 PRO D CD  1 
ATOM   2932 N  N   . ARG B 2 241 ? 86.600  111.642 135.010 1.00 83.79  ? 241 ARG D N   1 
ATOM   2933 C  CA  . ARG B 2 241 ? 86.479  111.706 136.460 1.00 83.79  ? 241 ARG D CA  1 
ATOM   2934 C  C   . ARG B 2 241 ? 87.655  111.077 137.197 1.00 83.79  ? 241 ARG D C   1 
ATOM   2935 O  O   . ARG B 2 241 ? 87.744  111.224 138.420 1.00 83.79  ? 241 ARG D O   1 
ATOM   2936 C  CB  . ARG B 2 241 ? 85.182  111.024 136.909 1.00 83.79  ? 241 ARG D CB  1 
ATOM   2937 C  CG  . ARG B 2 241 ? 83.924  111.614 136.294 1.00 83.79  ? 241 ARG D CG  1 
ATOM   2938 C  CD  . ARG B 2 241 ? 83.699  113.040 136.763 1.00 83.79  ? 241 ARG D CD  1 
ATOM   2939 N  NE  . ARG B 2 241 ? 83.696  113.139 138.218 1.00 83.79  ? 241 ARG D NE  1 
ATOM   2940 C  CZ  . ARG B 2 241 ? 82.654  112.851 138.987 1.00 83.79  ? 241 ARG D CZ  1 
ATOM   2941 N  NH1 . ARG B 2 241 ? 81.507  112.442 138.471 1.00 83.79  ? 241 ARG D NH1 1 
ATOM   2942 N  NH2 . ARG B 2 241 ? 82.767  112.979 140.306 1.00 83.79  ? 241 ARG D NH2 1 
ATOM   2943 N  N   . ASN B 2 242 ? 88.553  110.384 136.496 1.00 76.36  ? 242 ASN D N   1 
ATOM   2944 C  CA  . ASN B 2 242 ? 89.664  109.702 137.144 1.00 76.36  ? 242 ASN D CA  1 
ATOM   2945 C  C   . ASN B 2 242 ? 90.984  109.804 136.396 1.00 76.36  ? 242 ASN D C   1 
ATOM   2946 O  O   . ASN B 2 242 ? 91.869  108.980 136.647 1.00 76.36  ? 242 ASN D O   1 
ATOM   2947 C  CB  . ASN B 2 242 ? 89.336  108.214 137.346 1.00 76.36  ? 242 ASN D CB  1 
ATOM   2948 C  CG  . ASN B 2 242 ? 88.156  107.996 138.268 1.00 76.36  ? 242 ASN D CG  1 
ATOM   2949 O  OD1 . ASN B 2 242 ? 88.319  107.822 139.475 1.00 76.36  ? 242 ASN D OD1 1 
ATOM   2950 N  ND2 . ASN B 2 242 ? 86.955  108.002 137.702 1.00 76.36  ? 242 ASN D ND2 1 
ATOM   2951 N  N   . HIS B 2 243 ? 91.153  110.776 135.497 1.00 68.68  ? 243 HIS D N   1 
ATOM   2952 C  CA  . HIS B 2 243 ? 92.347  110.805 134.658 1.00 68.68  ? 243 HIS D CA  1 
ATOM   2953 C  C   . HIS B 2 243 ? 93.607  111.074 135.471 1.00 68.68  ? 243 HIS D C   1 
ATOM   2954 O  O   . HIS B 2 243 ? 94.695  110.610 135.111 1.00 68.68  ? 243 HIS D O   1 
ATOM   2955 C  CB  . HIS B 2 243 ? 92.185  111.849 133.550 1.00 68.68  ? 243 HIS D CB  1 
ATOM   2956 C  CG  . HIS B 2 243 ? 92.087  113.256 134.050 1.00 68.68  ? 243 HIS D CG  1 
ATOM   2957 N  ND1 . HIS B 2 243 ? 93.172  113.954 134.534 1.00 68.68  ? 243 HIS D ND1 1 
ATOM   2958 C  CD2 . HIS B 2 243 ? 91.029  114.097 134.137 1.00 68.68  ? 243 HIS D CD2 1 
ATOM   2959 C  CE1 . HIS B 2 243 ? 92.787  115.164 134.901 1.00 68.68  ? 243 HIS D CE1 1 
ATOM   2960 N  NE2 . HIS B 2 243 ? 91.492  115.276 134.670 1.00 68.68  ? 243 HIS D NE2 1 
ATOM   2961 N  N   . LYS B 2 244 ? 93.483  111.815 136.575 1.00 64.63  ? 244 LYS D N   1 
ATOM   2962 C  CA  . LYS B 2 244 ? 94.667  112.212 137.332 1.00 64.63  ? 244 LYS D CA  1 
ATOM   2963 C  C   . LYS B 2 244 ? 95.374  111.007 137.944 1.00 64.63  ? 244 LYS D C   1 
ATOM   2964 O  O   . LYS B 2 244 ? 96.590  110.842 137.781 1.00 64.63  ? 244 LYS D O   1 
ATOM   2965 C  CB  . LYS B 2 244 ? 94.280  113.216 138.418 1.00 64.63  ? 244 LYS D CB  1 
ATOM   2966 C  CG  . LYS B 2 244 ? 95.460  113.951 139.034 1.00 64.63  ? 244 LYS D CG  1 
ATOM   2967 C  CD  . LYS B 2 244 ? 95.006  115.205 139.766 1.00 64.63  ? 244 LYS D CD  1 
ATOM   2968 C  CE  . LYS B 2 244 ? 95.787  115.411 141.055 1.00 64.63  ? 244 LYS D CE  1 
ATOM   2969 N  NZ  . LYS B 2 244 ? 96.976  116.285 140.853 1.00 64.63  ? 244 LYS D NZ  1 
ATOM   2970 N  N   . ARG B 2 245 ? 94.632  110.146 138.641 1.00 65.30  ? 245 ARG D N   1 
ATOM   2971 C  CA  . ARG B 2 245 ? 95.265  109.010 139.301 1.00 65.30  ? 245 ARG D CA  1 
ATOM   2972 C  C   . ARG B 2 245 ? 95.718  107.955 138.298 1.00 65.30  ? 245 ARG D C   1 
ATOM   2973 O  O   . ARG B 2 245 ? 96.741  107.295 138.512 1.00 65.30  ? 245 ARG D O   1 
ATOM   2974 C  CB  . ARG B 2 245 ? 94.316  108.402 140.333 1.00 65.30  ? 245 ARG D CB  1 
ATOM   2975 C  CG  . ARG B 2 245 ? 95.037  107.717 141.480 1.00 65.30  ? 245 ARG D CG  1 
ATOM   2976 C  CD  . ARG B 2 245 ? 94.077  107.286 142.571 1.00 65.30  ? 245 ARG D CD  1 
ATOM   2977 N  NE  . ARG B 2 245 ? 94.784  106.866 143.776 1.00 65.30  ? 245 ARG D NE  1 
ATOM   2978 C  CZ  . ARG B 2 245 ? 95.221  107.694 144.715 1.00 65.30  ? 245 ARG D CZ  1 
ATOM   2979 N  NH1 . ARG B 2 245 ? 95.038  109.001 144.624 1.00 65.30  ? 245 ARG D NH1 1 
ATOM   2980 N  NH2 . ARG B 2 245 ? 95.859  107.198 145.771 1.00 65.30  ? 245 ARG D NH2 1 
ATOM   2981 N  N   . ILE B 2 246 ? 94.978  107.783 137.201 1.00 56.05  ? 246 ILE D N   1 
ATOM   2982 C  CA  . ILE B 2 246 ? 95.418  106.867 136.150 1.00 56.05  ? 246 ILE D CA  1 
ATOM   2983 C  C   . ILE B 2 246 ? 96.729  107.352 135.544 1.00 56.05  ? 246 ILE D C   1 
ATOM   2984 O  O   . ILE B 2 246 ? 97.652  106.565 135.303 1.00 56.05  ? 246 ILE D O   1 
ATOM   2985 C  CB  . ILE B 2 246 ? 94.325  106.705 135.079 1.00 56.05  ? 246 ILE D CB  1 
ATOM   2986 C  CG1 . ILE B 2 246 ? 93.026  106.208 135.713 1.00 56.05  ? 246 ILE D CG1 1 
ATOM   2987 C  CG2 . ILE B 2 246 ? 94.785  105.752 133.990 1.00 56.05  ? 246 ILE D CG2 1 
ATOM   2988 C  CD1 . ILE B 2 246 ? 93.179  104.924 136.493 1.00 56.05  ? 246 ILE D CD1 1 
ATOM   2989 N  N   . LEU B 2 247 ? 96.829  108.659 135.288 1.00 52.54  ? 247 LEU D N   1 
ATOM   2990 C  CA  . LEU B 2 247 ? 98.072  109.217 134.769 1.00 52.54  ? 247 LEU D CA  1 
ATOM   2991 C  C   . LEU B 2 247 ? 99.209  109.054 135.768 1.00 52.54  ? 247 LEU D C   1 
ATOM   2992 O  O   . LEU B 2 247 ? 100.347 108.771 135.380 1.00 52.54  ? 247 LEU D O   1 
ATOM   2993 C  CB  . LEU B 2 247 ? 97.881  110.689 134.408 1.00 52.54  ? 247 LEU D CB  1 
ATOM   2994 C  CG  . LEU B 2 247 ? 97.210  110.962 133.062 1.00 52.54  ? 247 LEU D CG  1 
ATOM   2995 C  CD1 . LEU B 2 247 ? 96.793  112.418 132.957 1.00 52.54  ? 247 LEU D CD1 1 
ATOM   2996 C  CD2 . LEU B 2 247 ? 98.139  110.584 131.922 1.00 52.54  ? 247 LEU D CD2 1 
ATOM   2997 N  N   . ALA B 2 248 ? 98.924  109.238 137.059 1.00 50.36  ? 248 ALA D N   1 
ATOM   2998 C  CA  . ALA B 2 248 ? 99.956  109.036 138.072 1.00 50.36  ? 248 ALA D CA  1 
ATOM   2999 C  C   . ALA B 2 248 ? 100.442 107.592 138.101 1.00 50.36  ? 248 ALA D C   1 
ATOM   3000 O  O   . ALA B 2 248 ? 101.651 107.345 138.188 1.00 50.36  ? 248 ALA D O   1 
ATOM   3001 C  CB  . ALA B 2 248 ? 99.433  109.449 139.447 1.00 50.36  ? 248 ALA D CB  1 
ATOM   3002 N  N   . PHE B 2 249 ? 99.521  106.629 138.023 1.00 46.15  ? 249 PHE D N   1 
ATOM   3003 C  CA  . PHE B 2 249 ? 99.919  105.225 137.990 1.00 46.15  ? 249 PHE D CA  1 
ATOM   3004 C  C   . PHE B 2 249 ? 100.737 104.910 136.742 1.00 46.15  ? 249 PHE D C   1 
ATOM   3005 O  O   . PHE B 2 249 ? 101.736 104.184 136.814 1.00 46.15  ? 249 PHE D O   1 
ATOM   3006 C  CB  . PHE B 2 249 ? 98.687  104.325 138.062 1.00 46.15  ? 249 PHE D CB  1 
ATOM   3007 C  CG  . PHE B 2 249 ? 98.154  104.135 139.453 1.00 46.15  ? 249 PHE D CG  1 
ATOM   3008 C  CD1 . PHE B 2 249 ? 98.976  103.677 140.467 1.00 46.15  ? 249 PHE D CD1 1 
ATOM   3009 C  CD2 . PHE B 2 249 ? 96.829  104.406 139.744 1.00 46.15  ? 249 PHE D CD2 1 
ATOM   3010 C  CE1 . PHE B 2 249 ? 98.489  103.499 141.745 1.00 46.15  ? 249 PHE D CE1 1 
ATOM   3011 C  CE2 . PHE B 2 249 ? 96.336  104.230 141.020 1.00 46.15  ? 249 PHE D CE2 1 
ATOM   3012 C  CZ  . PHE B 2 249 ? 97.167  103.775 142.022 1.00 46.15  ? 249 PHE D CZ  1 
ATOM   3013 N  N   . ILE B 2 250 ? 100.325 105.444 135.590 1.00 39.13  ? 250 ILE D N   1 
ATOM   3014 C  CA  . ILE B 2 250 ? 101.068 105.210 134.354 1.00 39.13  ? 250 ILE D CA  1 
ATOM   3015 C  C   . ILE B 2 250 ? 102.471 105.791 134.459 1.00 39.13  ? 250 ILE D C   1 
ATOM   3016 O  O   . ILE B 2 250 ? 103.456 105.148 134.075 1.00 39.13  ? 250 ILE D O   1 
ATOM   3017 C  CB  . ILE B 2 250 ? 100.299 105.789 133.152 1.00 39.13  ? 250 ILE D CB  1 
ATOM   3018 C  CG1 . ILE B 2 250 ? 99.103  104.901 132.809 1.00 39.13  ? 250 ILE D CG1 1 
ATOM   3019 C  CG2 . ILE B 2 250 ? 101.207 105.926 131.950 1.00 39.13  ? 250 ILE D CG2 1 
ATOM   3020 C  CD1 . ILE B 2 250 ? 98.313  105.381 131.616 1.00 39.13  ? 250 ILE D CD1 1 
ATOM   3021 N  N   . ASP B 2 251 ? 102.587 107.011 134.989 1.00 43.58  ? 251 ASP D N   1 
ATOM   3022 C  CA  . ASP B 2 251 ? 103.893 107.624 135.192 1.00 43.58  ? 251 ASP D CA  1 
ATOM   3023 C  C   . ASP B 2 251 ? 104.757 106.822 136.153 1.00 43.58  ? 251 ASP D C   1 
ATOM   3024 O  O   . ASP B 2 251 ? 105.973 106.737 135.954 1.00 43.58  ? 251 ASP D O   1 
ATOM   3025 C  CB  . ASP B 2 251 ? 103.722 109.053 135.706 1.00 43.58  ? 251 ASP D CB  1 
ATOM   3026 C  CG  . ASP B 2 251 ? 105.043 109.762 135.900 1.00 43.58  ? 251 ASP D CG  1 
ATOM   3027 O  OD1 . ASP B 2 251 ? 105.813 109.861 134.922 1.00 43.58  ? 251 ASP D OD1 1 
ATOM   3028 O  OD2 . ASP B 2 251 ? 105.309 110.223 137.029 1.00 43.58  ? 251 ASP D OD2 1 
ATOM   3029 N  N   . GLU B 2 252 ? 104.159 106.239 137.190 1.00 48.34  ? 252 GLU D N   1 
ATOM   3030 C  CA  . GLU B 2 252 ? 104.878 105.322 138.064 1.00 48.34  ? 252 GLU D CA  1 
ATOM   3031 C  C   . GLU B 2 252 ? 105.365 104.082 137.329 1.00 48.34  ? 252 GLU D C   1 
ATOM   3032 O  O   . GLU B 2 252 ? 106.474 103.608 137.597 1.00 48.34  ? 252 GLU D O   1 
ATOM   3033 C  CB  . GLU B 2 252 ? 103.986 104.905 139.238 1.00 48.34  ? 252 GLU D CB  1 
ATOM   3034 C  CG  . GLU B 2 252 ? 104.565 103.803 140.105 1.00 48.34  ? 252 GLU D CG  1 
ATOM   3035 C  CD  . GLU B 2 252 ? 105.280 104.341 141.327 1.00 48.34  ? 252 GLU D CD  1 
ATOM   3036 O  OE1 . GLU B 2 252 ? 105.797 103.529 142.122 1.00 48.34  ? 252 GLU D OE1 1 
ATOM   3037 O  OE2 . GLU B 2 252 ? 105.325 105.578 141.492 1.00 48.34  ? 252 GLU D OE2 1 
ATOM   3038 N  N   . VAL B 2 253 ? 104.559 103.547 136.408 1.00 38.62  ? 253 VAL D N   1 
ATOM   3039 C  CA  . VAL B 2 253 ? 104.964 102.361 135.655 1.00 38.62  ? 253 VAL D CA  1 
ATOM   3040 C  C   . VAL B 2 253 ? 106.174 102.671 134.780 1.00 38.62  ? 253 VAL D C   1 
ATOM   3041 O  O   . VAL B 2 253 ? 107.100 101.861 134.661 1.00 38.62  ? 253 VAL D O   1 
ATOM   3042 C  CB  . VAL B 2 253 ? 103.785 101.825 134.823 1.00 38.62  ? 253 VAL D CB  1 
ATOM   3043 C  CG1 . VAL B 2 253 ? 104.275 100.862 133.756 1.00 38.62  ? 253 VAL D CG1 1 
ATOM   3044 C  CG2 . VAL B 2 253 ? 102.771 101.149 135.725 1.00 38.62  ? 253 VAL D CG2 1 
ATOM   3045 N  N   . TYR B 2 254 ? 106.187 103.856 134.159 1.00 36.41  ? 254 TYR D N   1 
ATOM   3046 C  CA  . TYR B 2 254 ? 107.294 104.234 133.283 1.00 36.41  ? 254 TYR D CA  1 
ATOM   3047 C  C   . TYR B 2 254 ? 108.625 104.251 134.021 1.00 36.41  ? 254 TYR D C   1 
ATOM   3048 O  O   . TYR B 2 254 ? 109.685 104.144 133.394 1.00 36.41  ? 254 TYR D O   1 
ATOM   3049 C  CB  . TYR B 2 254 ? 107.042 105.611 132.670 1.00 36.41  ? 254 TYR D CB  1 
ATOM   3050 C  CG  . TYR B 2 254 ? 105.921 105.665 131.662 1.00 36.41  ? 254 TYR D CG  1 
ATOM   3051 C  CD1 . TYR B 2 254 ? 105.405 104.508 131.102 1.00 36.41  ? 254 TYR D CD1 1 
ATOM   3052 C  CD2 . TYR B 2 254 ? 105.386 106.881 131.263 1.00 36.41  ? 254 TYR D CD2 1 
ATOM   3053 C  CE1 . TYR B 2 254 ? 104.382 104.560 130.180 1.00 36.41  ? 254 TYR D CE1 1 
ATOM   3054 C  CE2 . TYR B 2 254 ? 104.366 106.942 130.342 1.00 36.41  ? 254 TYR D CE2 1 
ATOM   3055 C  CZ  . TYR B 2 254 ? 103.869 105.780 129.801 1.00 36.41  ? 254 TYR D CZ  1 
ATOM   3056 O  OH  . TYR B 2 254 ? 102.849 105.839 128.882 1.00 36.41  ? 254 TYR D OH  1 
ATOM   3057 N  N   . ARG B 2 255 ? 108.591 104.393 135.346 1.00 38.24  ? 255 ARG D N   1 
ATOM   3058 C  CA  . ARG B 2 255 ? 109.818 104.565 136.113 1.00 38.24  ? 255 ARG D CA  1 
ATOM   3059 C  C   . ARG B 2 255 ? 110.691 103.316 136.098 1.00 38.24  ? 255 ARG D C   1 
ATOM   3060 O  O   . ARG B 2 255 ? 111.922 103.424 136.075 1.00 38.24  ? 255 ARG D O   1 
ATOM   3061 C  CB  . ARG B 2 255 ? 109.471 104.953 137.550 1.00 38.24  ? 255 ARG D CB  1 
ATOM   3062 C  CG  . ARG B 2 255 ? 110.646 105.418 138.382 1.00 38.24  ? 255 ARG D CG  1 
ATOM   3063 C  CD  . ARG B 2 255 ? 110.384 105.187 139.860 1.00 38.24  ? 255 ARG D CD  1 
ATOM   3064 N  NE  . ARG B 2 255 ? 109.318 106.043 140.364 1.00 38.24  ? 255 ARG D NE  1 
ATOM   3065 C  CZ  . ARG B 2 255 ? 109.516 107.201 140.980 1.00 38.24  ? 255 ARG D CZ  1 
ATOM   3066 N  NH1 . ARG B 2 255 ? 110.734 107.670 141.193 1.00 38.24  ? 255 ARG D NH1 1 
ATOM   3067 N  NH2 . ARG B 2 255 ? 108.466 107.904 141.392 1.00 38.24  ? 255 ARG D NH2 1 
ATOM   3068 N  N   . TRP B 2 256 ? 110.086 102.128 136.105 1.00 31.18  ? 256 TRP D N   1 
ATOM   3069 C  CA  . TRP B 2 256 ? 110.821 100.897 136.358 1.00 31.18  ? 256 TRP D CA  1 
ATOM   3070 C  C   . TRP B 2 256 ? 111.018 100.011 135.135 1.00 31.18  ? 256 TRP D C   1 
ATOM   3071 O  O   . TRP B 2 256 ? 111.503 98.885  135.290 1.00 31.18  ? 256 TRP D O   1 
ATOM   3072 C  CB  . TRP B 2 256 ? 110.117 100.083 137.453 1.00 31.18  ? 256 TRP D CB  1 
ATOM   3073 C  CG  . TRP B 2 256 ? 110.091 100.768 138.784 1.00 31.18  ? 256 TRP D CG  1 
ATOM   3074 C  CD1 . TRP B 2 256 ? 109.010 101.333 139.392 1.00 31.18  ? 256 TRP D CD1 1 
ATOM   3075 C  CD2 . TRP B 2 256 ? 111.196 100.955 139.675 1.00 31.18  ? 256 TRP D CD2 1 
ATOM   3076 N  NE1 . TRP B 2 256 ? 109.373 101.863 140.605 1.00 31.18  ? 256 TRP D NE1 1 
ATOM   3077 C  CE2 . TRP B 2 256 ? 110.711 101.644 140.802 1.00 31.18  ? 256 TRP D CE2 1 
ATOM   3078 C  CE3 . TRP B 2 256 ? 112.550 100.608 139.628 1.00 31.18  ? 256 TRP D CE3 1 
ATOM   3079 C  CZ2 . TRP B 2 256 ? 111.530 101.993 141.872 1.00 31.18  ? 256 TRP D CZ2 1 
ATOM   3080 C  CZ3 . TRP B 2 256 ? 113.360 100.955 140.691 1.00 31.18  ? 256 TRP D CZ3 1 
ATOM   3081 C  CH2 . TRP B 2 256 ? 112.848 101.640 141.798 1.00 31.18  ? 256 TRP D CH2 1 
ATOM   3082 N  N   . LEU B 2 257 ? 110.665 100.469 133.940 1.00 28.27  ? 257 LEU D N   1 
ATOM   3083 C  CA  . LEU B 2 257 ? 110.845 99.643  132.753 1.00 28.27  ? 257 LEU D CA  1 
ATOM   3084 C  C   . LEU B 2 257 ? 112.333 99.436  132.480 1.00 28.27  ? 257 LEU D C   1 
ATOM   3085 O  O   . LEU B 2 257 ? 113.114 100.391 132.585 1.00 28.27  ? 257 LEU D O   1 
ATOM   3086 C  CB  . LEU B 2 257 ? 110.171 100.282 131.542 1.00 28.27  ? 257 LEU D CB  1 
ATOM   3087 C  CG  . LEU B 2 257 ? 108.644 100.213 131.507 1.00 28.27  ? 257 LEU D CG  1 
ATOM   3088 C  CD1 . LEU B 2 257 ? 108.094 101.032 130.354 1.00 28.27  ? 257 LEU D CD1 1 
ATOM   3089 C  CD2 . LEU B 2 257 ? 108.183 98.773  131.406 1.00 28.27  ? 257 LEU D CD2 1 
ATOM   3090 N  N   . PRO B 2 258 ? 112.762 98.223  132.134 1.00 26.11  ? 258 PRO D N   1 
ATOM   3091 C  CA  . PRO B 2 258 ? 114.189 97.985  131.887 1.00 26.11  ? 258 PRO D CA  1 
ATOM   3092 C  C   . PRO B 2 258 ? 114.702 98.804  130.711 1.00 26.11  ? 258 PRO D C   1 
ATOM   3093 O  O   . PRO B 2 258 ? 113.965 99.117  129.775 1.00 26.11  ? 258 PRO D O   1 
ATOM   3094 C  CB  . PRO B 2 258 ? 114.250 96.482  131.593 1.00 26.11  ? 258 PRO D CB  1 
ATOM   3095 C  CG  . PRO B 2 258 ? 113.029 95.921  132.236 1.00 26.11  ? 258 PRO D CG  1 
ATOM   3096 C  CD  . PRO B 2 258 ? 111.979 96.979  132.090 1.00 26.11  ? 258 PRO D CD  1 
ATOM   3097 N  N   . LEU B 2 259 ? 115.988 99.158  130.774 1.00 24.16  ? 259 LEU D N   1 
ATOM   3098 C  CA  . LEU B 2 259 ? 116.592 100.006 129.754 1.00 24.16  ? 259 LEU D CA  1 
ATOM   3099 C  C   . LEU B 2 259 ? 117.043 99.236  128.521 1.00 24.16  ? 259 LEU D C   1 
ATOM   3100 O  O   . LEU B 2 259 ? 117.322 99.857  127.490 1.00 24.16  ? 259 LEU D O   1 
ATOM   3101 C  CB  . LEU B 2 259 ? 117.782 100.766 130.342 1.00 24.16  ? 259 LEU D CB  1 
ATOM   3102 C  CG  . LEU B 2 259 ? 117.466 101.723 131.490 1.00 24.16  ? 259 LEU D CG  1 
ATOM   3103 C  CD1 . LEU B 2 259 ? 118.745 102.228 132.128 1.00 24.16  ? 259 LEU D CD1 1 
ATOM   3104 C  CD2 . LEU B 2 259 ? 116.620 102.882 130.998 1.00 24.16  ? 259 LEU D CD2 1 
ATOM   3105 N  N   . GLY B 2 260 ? 117.123 97.914  128.595 1.00 30.84  ? 260 GLY D N   1 
ATOM   3106 C  CA  . GLY B 2 260 ? 117.571 97.137  127.454 1.00 30.84  ? 260 GLY D CA  1 
ATOM   3107 C  C   . GLY B 2 260 ? 117.501 95.660  127.763 1.00 30.84  ? 260 GLY D C   1 
ATOM   3108 O  O   . GLY B 2 260 ? 117.119 95.246  128.862 1.00 30.84  ? 260 GLY D O   1 
ATOM   3109 N  N   . SER B 2 261 ? 117.878 94.861  126.768 1.00 28.89  ? 261 SER D N   1 
ATOM   3110 C  CA  . SER B 2 261 ? 117.854 93.413  126.894 1.00 28.89  ? 261 SER D CA  1 
ATOM   3111 C  C   . SER B 2 261 ? 119.054 92.818  126.177 1.00 28.89  ? 261 SER D C   1 
ATOM   3112 O  O   . SER B 2 261 ? 119.470 93.317  125.128 1.00 28.89  ? 261 SER D O   1 
ATOM   3113 C  CB  . SER B 2 261 ? 116.559 92.827  126.324 1.00 28.89  ? 261 SER D CB  1 
ATOM   3114 O  OG  . SER B 2 261 ? 115.428 93.360  126.989 1.00 28.89  ? 261 SER D OG  1 
ATOM   3115 N  N   . VAL B 2 262 ? 119.606 91.753  126.749 1.00 29.37  ? 262 VAL D N   1 
ATOM   3116 C  CA  . VAL B 2 262 ? 120.744 91.041  126.181 1.00 29.37  ? 262 VAL D CA  1 
ATOM   3117 C  C   . VAL B 2 262 ? 120.293 89.626  125.850 1.00 29.37  ? 262 VAL D C   1 
ATOM   3118 O  O   . VAL B 2 262 ? 119.783 88.912  126.720 1.00 29.37  ? 262 VAL D O   1 
ATOM   3119 C  CB  . VAL B 2 262 ? 121.945 91.031  127.143 1.00 29.37  ? 262 VAL D CB  1 
ATOM   3120 C  CG1 . VAL B 2 262 ? 122.884 89.892  126.809 1.00 29.37  ? 262 VAL D CG1 1 
ATOM   3121 C  CG2 . VAL B 2 262 ? 122.678 92.358  127.082 1.00 29.37  ? 262 VAL D CG2 1 
ATOM   3122 N  N   . LEU B 2 263 ? 120.482 89.225  124.595 1.00 30.75  ? 263 LEU D N   1 
ATOM   3123 C  CA  . LEU B 2 263 ? 119.950 87.973  124.073 1.00 30.75  ? 263 LEU D CA  1 
ATOM   3124 C  C   . LEU B 2 263 ? 121.080 86.962  123.955 1.00 30.75  ? 263 LEU D C   1 
ATOM   3125 O  O   . LEU B 2 263 ? 122.062 87.206  123.246 1.00 30.75  ? 263 LEU D O   1 
ATOM   3126 C  CB  . LEU B 2 263 ? 119.282 88.199  122.715 1.00 30.75  ? 263 LEU D CB  1 
ATOM   3127 C  CG  . LEU B 2 263 ? 118.141 87.271  122.305 1.00 30.75  ? 263 LEU D CG  1 
ATOM   3128 C  CD1 . LEU B 2 263 ? 117.258 87.963  121.284 1.00 30.75  ? 263 LEU D CD1 1 
ATOM   3129 C  CD2 . LEU B 2 263 ? 118.680 85.966  121.746 1.00 30.75  ? 263 LEU D CD2 1 
ATOM   3130 N  N   . ASN B 2 264 ? 120.938 85.831  124.651 1.00 34.53  ? 264 ASN D N   1 
ATOM   3131 C  CA  . ASN B 2 264 ? 121.901 84.728  124.608 1.00 34.53  ? 264 ASN D CA  1 
ATOM   3132 C  C   . ASN B 2 264 ? 123.307 85.171  124.998 1.00 34.53  ? 264 ASN D C   1 
ATOM   3133 O  O   . ASN B 2 264 ? 124.289 84.514  124.637 1.00 34.53  ? 264 ASN D O   1 
ATOM   3134 C  CB  . ASN B 2 264 ? 121.924 84.064  123.227 1.00 34.53  ? 264 ASN D CB  1 
ATOM   3135 C  CG  . ASN B 2 264 ? 120.958 82.905  123.123 1.00 34.53  ? 264 ASN D CG  1 
ATOM   3136 O  OD1 . ASN B 2 264 ? 120.128 82.854  122.216 1.00 34.53  ? 264 ASN D OD1 1 
ATOM   3137 N  ND2 . ASN B 2 264 ? 121.061 81.965  124.054 1.00 34.53  ? 264 ASN D ND2 1 
ATOM   3138 N  N   . SER B 2 265 ? 123.418 86.283  125.729 1.00 41.11  ? 265 SER D N   1 
ATOM   3139 C  CA  . SER B 2 265 ? 124.705 86.876  126.097 1.00 41.11  ? 265 SER D CA  1 
ATOM   3140 C  C   . SER B 2 265 ? 125.548 87.203  124.867 1.00 41.11  ? 265 SER D C   1 
ATOM   3141 O  O   . SER B 2 265 ? 126.773 87.318  124.953 1.00 41.11  ? 265 SER D O   1 
ATOM   3142 C  CB  . SER B 2 265 ? 125.484 85.974  127.059 1.00 41.11  ? 265 SER D CB  1 
ATOM   3143 O  OG  . SER B 2 265 ? 126.007 84.842  126.386 1.00 41.11  ? 265 SER D OG  1 
ATOM   3144 N  N   . ARG B 2 266 ? 124.899 87.352  123.712 1.00 35.67  ? 266 ARG D N   1 
ATOM   3145 C  CA  . ARG B 2 266 ? 125.603 87.637  122.466 1.00 35.67  ? 266 ARG D CA  1 
ATOM   3146 C  C   . ARG B 2 266 ? 125.001 88.772  121.648 1.00 35.67  ? 266 ARG D C   1 
ATOM   3147 O  O   . ARG B 2 266 ? 125.739 89.416  120.897 1.00 35.67  ? 266 ARG D O   1 
ATOM   3148 C  CB  . ARG B 2 266 ? 125.664 86.375  121.596 1.00 35.67  ? 266 ARG D CB  1 
ATOM   3149 C  CG  . ARG B 2 266 ? 126.731 86.406  120.519 1.00 35.67  ? 266 ARG D CG  1 
ATOM   3150 C  CD  . ARG B 2 266 ? 127.075 85.005  120.044 1.00 35.67  ? 266 ARG D CD  1 
ATOM   3151 N  NE  . ARG B 2 266 ? 126.061 84.463  119.148 1.00 35.67  ? 266 ARG D NE  1 
ATOM   3152 C  CZ  . ARG B 2 266 ? 125.534 83.252  119.259 1.00 35.67  ? 266 ARG D CZ  1 
ATOM   3153 N  NH1 . ARG B 2 266 ? 125.898 82.427  120.228 1.00 35.67  ? 266 ARG D NH1 1 
ATOM   3154 N  NH2 . ARG B 2 266 ? 124.622 82.856  118.376 1.00 35.67  ? 266 ARG D NH2 1 
ATOM   3155 N  N   . VAL B 2 267 ? 123.706 89.053  121.761 1.00 29.08  ? 267 VAL D N   1 
ATOM   3156 C  CA  . VAL B 2 267 ? 123.043 90.080  120.969 1.00 29.08  ? 267 VAL D CA  1 
ATOM   3157 C  C   . VAL B 2 267 ? 122.351 91.052  121.912 1.00 29.08  ? 267 VAL D C   1 
ATOM   3158 O  O   . VAL B 2 267 ? 121.618 90.637  122.817 1.00 29.08  ? 267 VAL D O   1 
ATOM   3159 C  CB  . VAL B 2 267 ? 122.031 89.466  119.982 1.00 29.08  ? 267 VAL D CB  1 
ATOM   3160 C  CG1 . VAL B 2 267 ? 121.202 90.553  119.322 1.00 29.08  ? 267 VAL D CG1 1 
ATOM   3161 C  CG2 . VAL B 2 267 ? 122.751 88.632  118.942 1.00 29.08  ? 267 VAL D CG2 1 
ATOM   3162 N  N   . LEU B 2 268 ? 122.579 92.343  121.698 1.00 31.68  ? 268 LEU D N   1 
ATOM   3163 C  CA  . LEU B 2 268 ? 122.002 93.396  122.521 1.00 31.68  ? 268 LEU D CA  1 
ATOM   3164 C  C   . LEU B 2 268 ? 120.783 93.976  121.820 1.00 31.68  ? 268 LEU D C   1 
ATOM   3165 O  O   . LEU B 2 268 ? 120.824 94.240  120.614 1.00 31.68  ? 268 LEU D O   1 
ATOM   3166 C  CB  . LEU B 2 268 ? 123.027 94.498  122.798 1.00 31.68  ? 268 LEU D CB  1 
ATOM   3167 C  CG  . LEU B 2 268 ? 122.514 95.766  123.481 1.00 31.68  ? 268 LEU D CG  1 
ATOM   3168 C  CD1 . LEU B 2 268 ? 122.272 95.519  124.959 1.00 31.68  ? 268 LEU D CD1 1 
ATOM   3169 C  CD2 . LEU B 2 268 ? 123.487 96.915  123.283 1.00 31.68  ? 268 LEU D CD2 1 
ATOM   3170 N  N   . ILE B 2 269 ? 119.704 94.167  122.572 1.00 38.94  ? 269 ILE D N   1 
ATOM   3171 C  CA  . ILE B 2 269 ? 118.479 94.775  122.064 1.00 38.94  ? 269 ILE D CA  1 
ATOM   3172 C  C   . ILE B 2 269 ? 118.232 96.058  122.842 1.00 38.94  ? 269 ILE D C   1 
ATOM   3173 O  O   . ILE B 2 269 ? 117.950 96.019  124.045 1.00 38.94  ? 269 ILE D O   1 
ATOM   3174 C  CB  . ILE B 2 269 ? 117.279 93.824  122.181 1.00 38.94  ? 269 ILE D CB  1 
ATOM   3175 C  CG1 . ILE B 2 269 ? 117.565 92.510  121.455 1.00 38.94  ? 269 ILE D CG1 1 
ATOM   3176 C  CG2 . ILE B 2 269 ? 116.027 94.482  121.630 1.00 38.94  ? 269 ILE D CG2 1 
ATOM   3177 C  CD1 . ILE B 2 269 ? 116.351 91.623  121.301 1.00 38.94  ? 269 ILE D CD1 1 
ATOM   3178 N  N   . VAL B 2 270 ? 118.335 97.196  122.154 1.00 51.63  ? 270 VAL D N   1 
ATOM   3179 C  CA  . VAL B 2 270 ? 118.056 98.502  122.736 1.00 51.63  ? 270 VAL D CA  1 
ATOM   3180 C  C   . VAL B 2 270 ? 117.102 99.233  121.805 1.00 51.63  ? 270 VAL D C   1 
ATOM   3181 O  O   . VAL B 2 270 ? 116.933 98.868  120.641 1.00 51.63  ? 270 VAL D O   1 
ATOM   3182 C  CB  . VAL B 2 270 ? 119.333 99.339  122.962 1.00 51.63  ? 270 VAL D CB  1 
ATOM   3183 C  CG1 . VAL B 2 270 ? 120.236 98.668  123.980 1.00 51.63  ? 270 VAL D CG1 1 
ATOM   3184 C  CG2 . VAL B 2 270 ? 120.068 99.545  121.654 1.00 51.63  ? 270 VAL D CG2 1 
ATOM   3185 N  N   . HIS B 2 271 ? 116.466 100.278 122.334 1.00 31.72  ? 271 HIS D N   1 
ATOM   3186 C  CA  . HIS B 2 271 ? 115.475 101.000 121.544 1.00 31.72  ? 271 HIS D CA  1 
ATOM   3187 C  C   . HIS B 2 271 ? 116.139 101.984 120.589 1.00 31.72  ? 271 HIS D C   1 
ATOM   3188 O  O   . HIS B 2 271 ? 115.929 101.926 119.373 1.00 31.72  ? 271 HIS D O   1 
ATOM   3189 C  CB  . HIS B 2 271 ? 114.493 101.729 122.456 1.00 31.72  ? 271 HIS D CB  1 
ATOM   3190 C  CG  . HIS B 2 271 ? 113.637 102.718 121.733 1.00 31.72  ? 271 HIS D CG  1 
ATOM   3191 N  ND1 . HIS B 2 271 ? 112.775 102.354 120.722 1.00 31.72  ? 271 HIS D ND1 1 
ATOM   3192 C  CD2 . HIS B 2 271 ? 113.521 104.060 121.860 1.00 31.72  ? 271 HIS D CD2 1 
ATOM   3193 C  CE1 . HIS B 2 271 ? 112.159 103.428 120.263 1.00 31.72  ? 271 HIS D CE1 1 
ATOM   3194 N  NE2 . HIS B 2 271 ? 112.592 104.476 120.938 1.00 31.72  ? 271 HIS D NE2 1 
ATOM   3195 N  N   . GLY B 2 272 ? 116.938 102.900 121.122 1.00 26.86  ? 272 GLY D N   1 
ATOM   3196 C  CA  . GLY B 2 272 ? 117.523 103.944 120.306 1.00 26.86  ? 272 GLY D CA  1 
ATOM   3197 C  C   . GLY B 2 272 ? 118.823 103.553 119.639 1.00 26.86  ? 272 GLY D C   1 
ATOM   3198 O  O   . GLY B 2 272 ? 118.968 103.689 118.422 1.00 26.86  ? 272 GLY D O   1 
ATOM   3199 N  N   . GLY B 2 273 ? 119.779 103.070 120.425 1.00 29.92  ? 273 GLY D N   1 
ATOM   3200 C  CA  . GLY B 2 273 ? 121.080 102.712 119.898 1.00 29.92  ? 273 GLY D CA  1 
ATOM   3201 C  C   . GLY B 2 273 ? 122.165 102.793 120.949 1.00 29.92  ? 273 GLY D C   1 
ATOM   3202 O  O   . GLY B 2 273 ? 122.004 102.260 122.051 1.00 29.92  ? 273 GLY D O   1 
ATOM   3203 N  N   . PHE B 2 274 ? 123.270 103.457 120.630 1.00 29.01  ? 274 PHE D N   1 
ATOM   3204 C  CA  . PHE B 2 274 ? 124.375 103.586 121.572 1.00 29.01  ? 274 PHE D CA  1 
ATOM   3205 C  C   . PHE B 2 274 ? 125.255 104.752 121.122 1.00 29.01  ? 274 PHE D C   1 
ATOM   3206 O  O   . PHE B 2 274 ? 124.872 105.526 120.241 1.00 29.01  ? 274 PHE D O   1 
ATOM   3207 C  CB  . PHE B 2 274 ? 125.153 102.264 121.682 1.00 29.01  ? 274 PHE D CB  1 
ATOM   3208 C  CG  . PHE B 2 274 ? 125.671 101.752 120.370 1.00 29.01  ? 274 PHE D CG  1 
ATOM   3209 C  CD1 . PHE B 2 274 ? 126.989 101.956 120.008 1.00 29.01  ? 274 PHE D CD1 1 
ATOM   3210 C  CD2 . PHE B 2 274 ? 124.846 101.053 119.506 1.00 29.01  ? 274 PHE D CD2 1 
ATOM   3211 C  CE1 . PHE B 2 274 ? 127.471 101.487 118.804 1.00 29.01  ? 274 PHE D CE1 1 
ATOM   3212 C  CE2 . PHE B 2 274 ? 125.323 100.582 118.302 1.00 29.01  ? 274 PHE D CE2 1 
ATOM   3213 C  CZ  . PHE B 2 274 ? 126.637 100.798 117.951 1.00 29.01  ? 274 PHE D CZ  1 
ATOM   3214 N  N   . SER B 2 275 ? 126.430 104.874 121.736 1.00 36.98  ? 275 SER D N   1 
ATOM   3215 C  CA  . SER B 2 275 ? 127.383 105.917 121.386 1.00 36.98  ? 275 SER D CA  1 
ATOM   3216 C  C   . SER B 2 275 ? 128.783 105.416 121.706 1.00 36.98  ? 275 SER D C   1 
ATOM   3217 O  O   . SER B 2 275 ? 128.963 104.308 122.215 1.00 36.98  ? 275 SER D O   1 
ATOM   3218 C  CB  . SER B 2 275 ? 127.094 107.223 122.130 1.00 36.98  ? 275 SER D CB  1 
ATOM   3219 O  OG  . SER B 2 275 ? 128.029 108.224 121.773 1.00 36.98  ? 275 SER D OG  1 
ATOM   3220 N  N   . ASP B 2 276 ? 129.776 106.253 121.399 1.00 41.86  ? 276 ASP D N   1 
ATOM   3221 C  CA  . ASP B 2 276 ? 131.165 105.865 121.616 1.00 41.86  ? 276 ASP D CA  1 
ATOM   3222 C  C   . ASP B 2 276 ? 131.510 105.718 123.092 1.00 41.86  ? 276 ASP D C   1 
ATOM   3223 O  O   . ASP B 2 276 ? 132.321 104.854 123.440 1.00 41.86  ? 276 ASP D O   1 
ATOM   3224 C  CB  . ASP B 2 276 ? 132.103 106.877 120.957 1.00 41.86  ? 276 ASP D CB  1 
ATOM   3225 C  CG  . ASP B 2 276 ? 131.979 108.263 121.554 1.00 41.86  ? 276 ASP D CG  1 
ATOM   3226 O  OD1 . ASP B 2 276 ? 130.921 108.564 122.145 1.00 41.86  ? 276 ASP D OD1 1 
ATOM   3227 O  OD2 . ASP B 2 276 ? 132.940 109.051 121.433 1.00 41.86  ? 276 ASP D OD2 1 
ATOM   3228 N  N   . SER B 2 277 ? 130.918 106.533 123.963 1.00 36.71  ? 277 SER D N   1 
ATOM   3229 C  CA  . SER B 2 277 ? 131.208 106.483 125.389 1.00 36.71  ? 277 SER D CA  1 
ATOM   3230 C  C   . SER B 2 277 ? 130.262 105.577 126.166 1.00 36.71  ? 277 SER D C   1 
ATOM   3231 O  O   . SER B 2 277 ? 130.422 105.445 127.384 1.00 36.71  ? 277 SER D O   1 
ATOM   3232 C  CB  . SER B 2 277 ? 131.163 107.894 125.989 1.00 36.71  ? 277 SER D CB  1 
ATOM   3233 O  OG  . SER B 2 277 ? 129.855 108.435 125.927 1.00 36.71  ? 277 SER D OG  1 
ATOM   3234 N  N   . THR B 2 278 ? 129.291 104.954 125.503 1.00 31.54  ? 278 THR D N   1 
ATOM   3235 C  CA  . THR B 2 278 ? 128.344 104.094 126.199 1.00 31.54  ? 278 THR D CA  1 
ATOM   3236 C  C   . THR B 2 278 ? 129.025 102.810 126.654 1.00 31.54  ? 278 THR D C   1 
ATOM   3237 O  O   . THR B 2 278 ? 129.711 102.145 125.873 1.00 31.54  ? 278 THR D O   1 
ATOM   3238 C  CB  . THR B 2 278 ? 127.158 103.771 125.291 1.00 31.54  ? 278 THR D CB  1 
ATOM   3239 O  OG1 . THR B 2 278 ? 126.431 104.972 125.007 1.00 31.54  ? 278 THR D OG1 1 
ATOM   3240 C  CG2 . THR B 2 278 ? 126.228 102.774 125.959 1.00 31.54  ? 278 THR D CG2 1 
ATOM   3241 N  N   . SER B 2 279 ? 128.836 102.465 127.926 1.00 36.00  ? 279 SER D N   1 
ATOM   3242 C  CA  . SER B 2 279 ? 129.421 101.249 128.486 1.00 36.00  ? 279 SER D CA  1 
ATOM   3243 C  C   . SER B 2 279 ? 128.331 100.510 129.248 1.00 36.00  ? 279 SER D C   1 
ATOM   3244 O  O   . SER B 2 279 ? 127.660 101.101 130.099 1.00 36.00  ? 279 SER D O   1 
ATOM   3245 C  CB  . SER B 2 279 ? 130.601 101.575 129.395 1.00 36.00  ? 279 SER D CB  1 
ATOM   3246 O  OG  . SER B 2 279 ? 131.594 102.307 128.698 1.00 36.00  ? 279 SER D OG  1 
ATOM   3247 N  N   . LEU B 2 280 ? 128.156 99.222  128.942 1.00 44.70  ? 280 LEU D N   1 
ATOM   3248 C  CA  . LEU B 2 280 ? 127.143 98.432  129.633 1.00 44.70  ? 280 LEU D CA  1 
ATOM   3249 C  C   . LEU B 2 280 ? 127.500 98.218  131.097 1.00 44.70  ? 280 LEU D C   1 
ATOM   3250 O  O   . LEU B 2 280 ? 126.611 97.988  131.924 1.00 44.70  ? 280 LEU D O   1 
ATOM   3251 C  CB  . LEU B 2 280 ? 126.952 97.089  128.929 1.00 44.70  ? 280 LEU D CB  1 
ATOM   3252 C  CG  . LEU B 2 280 ? 126.398 97.149  127.504 1.00 44.70  ? 280 LEU D CG  1 
ATOM   3253 C  CD1 . LEU B 2 280 ? 126.108 95.752  126.985 1.00 44.70  ? 280 LEU D CD1 1 
ATOM   3254 C  CD2 . LEU B 2 280 ? 125.150 98.014  127.448 1.00 44.70  ? 280 LEU D CD2 1 
ATOM   3255 N  N   . ASP B 2 281 ? 128.789 98.289  131.438 1.00 56.16  ? 281 ASP D N   1 
ATOM   3256 C  CA  . ASP B 2 281 ? 129.194 98.146  132.831 1.00 56.16  ? 281 ASP D CA  1 
ATOM   3257 C  C   . ASP B 2 281 ? 128.770 99.337  133.678 1.00 56.16  ? 281 ASP D C   1 
ATOM   3258 O  O   . ASP B 2 281 ? 128.849 99.268  134.909 1.00 56.16  ? 281 ASP D O   1 
ATOM   3259 C  CB  . ASP B 2 281 ? 130.708 97.952  132.922 1.00 56.16  ? 281 ASP D CB  1 
ATOM   3260 C  CG  . ASP B 2 281 ? 131.150 96.587  132.433 1.00 56.16  ? 281 ASP D CG  1 
ATOM   3261 O  OD1 . ASP B 2 281 ? 130.276 95.723  132.213 1.00 56.16  ? 281 ASP D OD1 1 
ATOM   3262 O  OD2 . ASP B 2 281 ? 132.370 96.379  132.267 1.00 56.16  ? 281 ASP D OD2 1 
ATOM   3263 N  N   . LEU B 2 282 ? 128.326 100.425 133.050 1.00 40.57  ? 282 LEU D N   1 
ATOM   3264 C  CA  . LEU B 2 282 ? 127.842 101.592 133.774 1.00 40.57  ? 282 LEU D CA  1 
ATOM   3265 C  C   . LEU B 2 282 ? 126.318 101.635 133.817 1.00 40.57  ? 282 LEU D C   1 
ATOM   3266 O  O   . LEU B 2 282 ? 125.735 102.045 134.825 1.00 40.57  ? 282 LEU D O   1 
ATOM   3267 C  CB  . LEU B 2 282 ? 128.391 102.871 133.134 1.00 40.57  ? 282 LEU D CB  1 
ATOM   3268 C  CG  . LEU B 2 282 ? 127.939 104.197 133.747 1.00 40.57  ? 282 LEU D CG  1 
ATOM   3269 C  CD1 . LEU B 2 282 ? 128.447 104.328 135.173 1.00 40.57  ? 282 LEU D CD1 1 
ATOM   3270 C  CD2 . LEU B 2 282 ? 128.408 105.366 132.899 1.00 40.57  ? 282 LEU D CD2 1 
ATOM   3271 N  N   . ILE B 2 283 ? 125.662 101.211 132.733 1.00 36.88  ? 283 ILE D N   1 
ATOM   3272 C  CA  . ILE B 2 283 ? 124.203 101.224 132.690 1.00 36.88  ? 283 ILE D CA  1 
ATOM   3273 C  C   . ILE B 2 283 ? 123.624 100.253 133.708 1.00 36.88  ? 283 ILE D C   1 
ATOM   3274 O  O   . ILE B 2 283 ? 122.580 100.524 134.315 1.00 36.88  ? 283 ILE D O   1 
ATOM   3275 C  CB  . ILE B 2 283 ? 123.709 100.910 131.264 1.00 36.88  ? 283 ILE D CB  1 
ATOM   3276 C  CG1 . ILE B 2 283 ? 124.191 101.978 130.285 1.00 36.88  ? 283 ILE D CG1 1 
ATOM   3277 C  CG2 . ILE B 2 283 ? 122.194 100.825 131.225 1.00 36.88  ? 283 ILE D CG2 1 
ATOM   3278 C  CD1 . ILE B 2 283 ? 124.081 101.565 128.838 1.00 36.88  ? 283 ILE D CD1 1 
ATOM   3279 N  N   . LYS B 2 284 ? 124.290 99.117  133.924 1.00 41.67  ? 284 LYS D N   1 
ATOM   3280 C  CA  . LYS B 2 284 ? 123.788 98.125  134.867 1.00 41.67  ? 284 LYS D CA  1 
ATOM   3281 C  C   . LYS B 2 284 ? 123.831 98.615  136.309 1.00 41.67  ? 284 LYS D C   1 
ATOM   3282 O  O   . LYS B 2 284 ? 123.214 97.991  137.180 1.00 41.67  ? 284 LYS D O   1 
ATOM   3283 C  CB  . LYS B 2 284 ? 124.589 96.829  134.735 1.00 41.67  ? 284 LYS D CB  1 
ATOM   3284 C  CG  . LYS B 2 284 ? 124.287 96.045  133.472 1.00 41.67  ? 284 LYS D CG  1 
ATOM   3285 C  CD  . LYS B 2 284 ? 125.172 94.817  133.358 1.00 41.67  ? 284 LYS D CD  1 
ATOM   3286 C  CE  . LYS B 2 284 ? 124.888 94.053  132.077 1.00 41.67  ? 284 LYS D CE  1 
ATOM   3287 N  NZ  . LYS B 2 284 ? 125.743 92.842  131.948 1.00 41.67  ? 284 LYS D NZ  1 
ATOM   3288 N  N   . SER B 2 285 ? 124.541 99.709  136.585 1.00 39.65  ? 285 SER D N   1 
ATOM   3289 C  CA  . SER B 2 285 ? 124.662 100.243 137.935 1.00 39.65  ? 285 SER D CA  1 
ATOM   3290 C  C   . SER B 2 285 ? 123.925 101.564 138.120 1.00 39.65  ? 285 SER D C   1 
ATOM   3291 O  O   . SER B 2 285 ? 124.077 102.205 139.165 1.00 39.65  ? 285 SER D O   1 
ATOM   3292 C  CB  . SER B 2 285 ? 126.138 100.411 138.303 1.00 39.65  ? 285 SER D CB  1 
ATOM   3293 O  OG  . SER B 2 285 ? 126.842 99.193  138.140 1.00 39.65  ? 285 SER D OG  1 
ATOM   3294 N  N   . ILE B 2 286 ? 123.133 101.989 137.135 1.00 37.41  ? 286 ILE D N   1 
ATOM   3295 C  CA  . ILE B 2 286 ? 122.371 103.224 137.269 1.00 37.41  ? 286 ILE D CA  1 
ATOM   3296 C  C   . ILE B 2 286 ? 121.125 102.970 138.106 1.00 37.41  ? 286 ILE D C   1 
ATOM   3297 O  O   . ILE B 2 286 ? 120.429 101.962 137.928 1.00 37.41  ? 286 ILE D O   1 
ATOM   3298 C  CB  . ILE B 2 286 ? 122.000 103.782 135.885 1.00 37.41  ? 286 ILE D CB  1 
ATOM   3299 C  CG1 . ILE B 2 286 ? 123.254 104.080 135.068 1.00 37.41  ? 286 ILE D CG1 1 
ATOM   3300 C  CG2 . ILE B 2 286 ? 121.159 105.038 136.019 1.00 37.41  ? 286 ILE D CG2 1 
ATOM   3301 C  CD1 . ILE B 2 286 ? 122.956 104.555 133.665 1.00 37.41  ? 286 ILE D CD1 1 
ATOM   3302 N  N   . ASP B 2 287 ? 120.837 103.887 139.027 1.00 44.31  ? 287 ASP D N   1 
ATOM   3303 C  CA  . ASP B 2 287 ? 119.611 103.824 139.821 1.00 44.31  ? 287 ASP D CA  1 
ATOM   3304 C  C   . ASP B 2 287 ? 118.453 104.196 138.903 1.00 44.31  ? 287 ASP D C   1 
ATOM   3305 O  O   . ASP B 2 287 ? 118.169 105.370 138.663 1.00 44.31  ? 287 ASP D O   1 
ATOM   3306 C  CB  . ASP B 2 287 ? 119.696 104.749 141.028 1.00 44.31  ? 287 ASP D CB  1 
ATOM   3307 C  CG  . ASP B 2 287 ? 118.534 104.566 141.984 1.00 44.31  ? 287 ASP D CG  1 
ATOM   3308 O  OD1 . ASP B 2 287 ? 117.820 103.548 141.868 1.00 44.31  ? 287 ASP D OD1 1 
ATOM   3309 O  OD2 . ASP B 2 287 ? 118.334 105.441 142.853 1.00 44.31  ? 287 ASP D OD2 1 
ATOM   3310 N  N   . ARG B 2 288 ? 117.778 103.170 138.383 1.00 34.12  ? 288 ARG D N   1 
ATOM   3311 C  CA  . ARG B 2 288 ? 116.754 103.381 137.365 1.00 34.12  ? 288 ARG D CA  1 
ATOM   3312 C  C   . ARG B 2 288 ? 115.565 104.164 137.907 1.00 34.12  ? 288 ARG D C   1 
ATOM   3313 O  O   . ARG B 2 288 ? 114.868 104.850 137.151 1.00 34.12  ? 288 ARG D O   1 
ATOM   3314 C  CB  . ARG B 2 288 ? 116.296 102.032 136.814 1.00 34.12  ? 288 ARG D CB  1 
ATOM   3315 C  CG  . ARG B 2 288 ? 115.522 102.106 135.518 1.00 34.12  ? 288 ARG D CG  1 
ATOM   3316 C  CD  . ARG B 2 288 ? 114.703 100.846 135.325 1.00 34.12  ? 288 ARG D CD  1 
ATOM   3317 N  NE  . ARG B 2 288 ? 115.388 99.670  135.847 1.00 34.12  ? 288 ARG D NE  1 
ATOM   3318 C  CZ  . ARG B 2 288 ? 114.787 98.672  136.480 1.00 34.12  ? 288 ARG D CZ  1 
ATOM   3319 N  NH1 . ARG B 2 288 ? 113.481 98.672  136.686 1.00 34.12  ? 288 ARG D NH1 1 
ATOM   3320 N  NH2 . ARG B 2 288 ? 115.514 97.649  136.917 1.00 34.12  ? 288 ARG D NH2 1 
ATOM   3321 N  N   . GLY B 2 289 ? 115.318 104.075 139.214 1.00 40.78  ? 289 GLY D N   1 
ATOM   3322 C  CA  . GLY B 2 289 ? 114.148 104.714 139.791 1.00 40.78  ? 289 GLY D CA  1 
ATOM   3323 C  C   . GLY B 2 289 ? 114.191 106.227 139.771 1.00 40.78  ? 289 GLY D C   1 
ATOM   3324 O  O   . GLY B 2 289 ? 113.139 106.869 139.861 1.00 40.78  ? 289 GLY D O   1 
ATOM   3325 N  N   . LYS B 2 290 ? 115.383 106.815 139.666 1.00 40.49  ? 290 LYS D N   1 
ATOM   3326 C  CA  . LYS B 2 290 ? 115.485 108.270 139.644 1.00 40.49  ? 290 LYS D CA  1 
ATOM   3327 C  C   . LYS B 2 290 ? 114.834 108.867 138.404 1.00 40.49  ? 290 LYS D C   1 
ATOM   3328 O  O   . LYS B 2 290 ? 114.153 109.894 138.498 1.00 40.49  ? 290 LYS D O   1 
ATOM   3329 C  CB  . LYS B 2 290 ? 116.951 108.696 139.718 1.00 40.49  ? 290 LYS D CB  1 
ATOM   3330 C  CG  . LYS B 2 290 ? 117.697 108.169 140.928 1.00 40.49  ? 290 LYS D CG  1 
ATOM   3331 C  CD  . LYS B 2 290 ? 119.082 108.785 141.021 1.00 40.49  ? 290 LYS D CD  1 
ATOM   3332 C  CE  . LYS B 2 290 ? 119.901 108.482 139.778 1.00 40.49  ? 290 LYS D CE  1 
ATOM   3333 N  NZ  . LYS B 2 290 ? 121.317 108.912 139.927 1.00 40.49  ? 290 LYS D NZ  1 
ATOM   3334 N  N   . TYR B 2 291 ? 115.023 108.243 137.247 1.00 40.60  ? 291 TYR D N   1 
ATOM   3335 C  CA  . TYR B 2 291 ? 114.626 108.830 135.968 1.00 40.60  ? 291 TYR D CA  1 
ATOM   3336 C  C   . TYR B 2 291 ? 113.167 108.515 135.649 1.00 40.60  ? 291 TYR D C   1 
ATOM   3337 O  O   . TYR B 2 291 ? 112.850 107.700 134.783 1.00 40.60  ? 291 TYR D O   1 
ATOM   3338 C  CB  . TYR B 2 291 ? 115.552 108.342 134.859 1.00 40.60  ? 291 TYR D CB  1 
ATOM   3339 C  CG  . TYR B 2 291 ? 117.008 108.650 135.110 1.00 40.60  ? 291 TYR D CG  1 
ATOM   3340 C  CD1 . TYR B 2 291 ? 117.555 109.866 134.732 1.00 40.60  ? 291 TYR D CD1 1 
ATOM   3341 C  CD2 . TYR B 2 291 ? 117.833 107.728 135.734 1.00 40.60  ? 291 TYR D CD2 1 
ATOM   3342 C  CE1 . TYR B 2 291 ? 118.884 110.151 134.963 1.00 40.60  ? 291 TYR D CE1 1 
ATOM   3343 C  CE2 . TYR B 2 291 ? 119.162 108.004 135.970 1.00 40.60  ? 291 TYR D CE2 1 
ATOM   3344 C  CZ  . TYR B 2 291 ? 119.683 109.216 135.583 1.00 40.60  ? 291 TYR D CZ  1 
ATOM   3345 O  OH  . TYR B 2 291 ? 121.009 109.493 135.817 1.00 40.60  ? 291 TYR D OH  1 
ATOM   3346 N  N   . VAL B 2 292 ? 112.265 109.185 136.370 1.00 36.51  ? 292 VAL D N   1 
ATOM   3347 C  CA  . VAL B 2 292 ? 110.851 109.110 136.031 1.00 36.51  ? 292 VAL D CA  1 
ATOM   3348 C  C   . VAL B 2 292 ? 110.595 109.744 134.672 1.00 36.51  ? 292 VAL D C   1 
ATOM   3349 O  O   . VAL B 2 292 ? 109.706 109.304 133.937 1.00 36.51  ? 292 VAL D O   1 
ATOM   3350 C  CB  . VAL B 2 292 ? 109.996 109.768 137.137 1.00 36.51  ? 292 VAL D CB  1 
ATOM   3351 C  CG1 . VAL B 2 292 ? 110.395 111.217 137.333 1.00 36.51  ? 292 VAL D CG1 1 
ATOM   3352 C  CG2 . VAL B 2 292 ? 108.516 109.656 136.813 1.00 36.51  ? 292 VAL D CG2 1 
ATOM   3353 N  N   . SER B 2 293 ? 111.369 110.765 134.314 1.00 33.74  ? 293 SER D N   1 
ATOM   3354 C  CA  . SER B 2 293 ? 111.306 111.377 132.998 1.00 33.74  ? 293 SER D CA  1 
ATOM   3355 C  C   . SER B 2 293 ? 112.723 111.517 132.465 1.00 33.74  ? 293 SER D C   1 
ATOM   3356 O  O   . SER B 2 293 ? 113.690 111.594 133.226 1.00 33.74  ? 293 SER D O   1 
ATOM   3357 C  CB  . SER B 2 293 ? 110.609 112.742 133.039 1.00 33.74  ? 293 SER D CB  1 
ATOM   3358 O  OG  . SER B 2 293 ? 110.681 113.382 131.778 1.00 33.74  ? 293 SER D OG  1 
ATOM   3359 N  N   . ILE B 2 294 ? 112.840 111.545 131.142 1.00 32.74  ? 294 ILE D N   1 
ATOM   3360 C  CA  . ILE B 2 294 ? 114.136 111.579 130.478 1.00 32.74  ? 294 ILE D CA  1 
ATOM   3361 C  C   . ILE B 2 294 ? 114.520 112.992 130.059 1.00 32.74  ? 294 ILE D C   1 
ATOM   3362 O  O   . ILE B 2 294 ? 115.669 113.399 130.227 1.00 32.74  ? 294 ILE D O   1 
ATOM   3363 C  CB  . ILE B 2 294 ? 114.134 110.615 129.272 1.00 32.74  ? 294 ILE D CB  1 
ATOM   3364 C  CG1 . ILE B 2 294 ? 114.550 109.212 129.712 1.00 32.74  ? 294 ILE D CG1 1 
ATOM   3365 C  CG2 . ILE B 2 294 ? 115.053 111.112 128.173 1.00 32.74  ? 294 ILE D CG2 1 
ATOM   3366 C  CD1 . ILE B 2 294 ? 114.379 108.168 128.638 1.00 32.74  ? 294 ILE D CD1 1 
ATOM   3367 N  N   . LEU B 2 295 ? 113.566 113.760 129.531 1.00 34.75  ? 295 LEU D N   1 
ATOM   3368 C  CA  . LEU B 2 295 ? 113.871 115.085 129.007 1.00 34.75  ? 295 LEU D CA  1 
ATOM   3369 C  C   . LEU B 2 295 ? 114.111 116.123 130.096 1.00 34.75  ? 295 LEU D C   1 
ATOM   3370 O  O   . LEU B 2 295 ? 114.628 117.203 129.794 1.00 34.75  ? 295 LEU D O   1 
ATOM   3371 C  CB  . LEU B 2 295 ? 112.743 115.559 128.090 1.00 34.75  ? 295 LEU D CB  1 
ATOM   3372 C  CG  . LEU B 2 295 ? 112.749 114.971 126.680 1.00 34.75  ? 295 LEU D CG  1 
ATOM   3373 C  CD1 . LEU B 2 295 ? 111.484 115.357 125.936 1.00 34.75  ? 295 LEU D CD1 1 
ATOM   3374 C  CD2 . LEU B 2 295 ? 113.983 115.421 125.919 1.00 34.75  ? 295 LEU D CD2 1 
ATOM   3375 N  N   . ARG B 2 296 ? 113.756 115.834 131.339 1.00 43.91  ? 296 ARG D N   1 
ATOM   3376 C  CA  . ARG B 2 296 ? 113.945 116.755 132.447 1.00 43.91  ? 296 ARG D CA  1 
ATOM   3377 C  C   . ARG B 2 296 ? 114.706 116.059 133.564 1.00 43.91  ? 296 ARG D C   1 
ATOM   3378 O  O   . ARG B 2 296 ? 114.680 114.828 133.669 1.00 43.91  ? 296 ARG D O   1 
ATOM   3379 C  CB  . ARG B 2 296 ? 112.599 117.300 132.953 1.00 43.91  ? 296 ARG D CB  1 
ATOM   3380 C  CG  . ARG B 2 296 ? 111.619 116.277 133.485 1.00 43.91  ? 296 ARG D CG  1 
ATOM   3381 C  CD  . ARG B 2 296 ? 110.345 116.984 133.925 1.00 43.91  ? 296 ARG D CD  1 
ATOM   3382 N  NE  . ARG B 2 296 ? 109.206 116.082 134.039 1.00 43.91  ? 296 ARG D NE  1 
ATOM   3383 C  CZ  . ARG B 2 296 ? 108.941 115.342 135.106 1.00 43.91  ? 296 ARG D CZ  1 
ATOM   3384 N  NH1 . ARG B 2 296 ? 109.719 115.369 136.176 1.00 43.91  ? 296 ARG D NH1 1 
ATOM   3385 N  NH2 . ARG B 2 296 ? 107.866 114.559 135.102 1.00 43.91  ? 296 ARG D NH2 1 
ATOM   3386 N  N   . PRO B 2 297 ? 115.408 116.817 134.407 1.00 45.97  ? 297 PRO D N   1 
ATOM   3387 C  CA  . PRO B 2 297 ? 116.391 116.205 135.296 1.00 45.97  ? 297 PRO D CA  1 
ATOM   3388 C  C   . PRO B 2 297 ? 115.734 115.249 136.270 1.00 45.97  ? 297 PRO D C   1 
ATOM   3389 O  O   . PRO B 2 297 ? 114.557 115.419 136.640 1.00 45.97  ? 297 PRO D O   1 
ATOM   3390 C  CB  . PRO B 2 297 ? 117.008 117.409 136.021 1.00 45.97  ? 297 PRO D CB  1 
ATOM   3391 C  CG  . PRO B 2 297 ? 116.786 118.549 135.099 1.00 45.97  ? 297 PRO D CG  1 
ATOM   3392 C  CD  . PRO B 2 297 ? 115.441 118.287 134.502 1.00 45.97  ? 297 PRO D CD  1 
ATOM   3393 N  N   . PRO B 2 298 ? 116.458 114.220 136.708 1.00 49.23  ? 298 PRO D N   1 
ATOM   3394 C  CA  . PRO B 2 298 ? 115.889 113.270 137.668 1.00 49.23  ? 298 PRO D CA  1 
ATOM   3395 C  C   . PRO B 2 298 ? 115.721 113.898 139.043 1.00 49.23  ? 298 PRO D C   1 
ATOM   3396 O  O   . PRO B 2 298 ? 116.396 114.866 139.398 1.00 49.23  ? 298 PRO D O   1 
ATOM   3397 C  CB  . PRO B 2 298 ? 116.922 112.140 137.696 1.00 49.23  ? 298 PRO D CB  1 
ATOM   3398 C  CG  . PRO B 2 298 ? 118.205 112.820 137.359 1.00 49.23  ? 298 PRO D CG  1 
ATOM   3399 C  CD  . PRO B 2 298 ? 117.851 113.889 136.363 1.00 49.23  ? 298 PRO D CD  1 
ATOM   3400 N  N   . LEU B 2 299 ? 114.804 113.324 139.823 1.00 62.22  ? 299 LEU D N   1 
ATOM   3401 C  CA  . LEU B 2 299 ? 114.514 113.803 141.176 1.00 62.22  ? 299 LEU D CA  1 
ATOM   3402 C  C   . LEU B 2 299 ? 115.420 113.084 142.176 1.00 62.22  ? 299 LEU D C   1 
ATOM   3403 O  O   . LEU B 2 299 ? 115.163 111.964 142.621 1.00 62.22  ? 299 LEU D O   1 
ATOM   3404 C  CB  . LEU B 2 299 ? 113.041 113.615 141.524 1.00 62.22  ? 299 LEU D CB  1 
ATOM   3405 C  CG  . LEU B 2 299 ? 111.896 114.264 140.727 1.00 62.22  ? 299 LEU D CG  1 
ATOM   3406 C  CD1 . LEU B 2 299 ? 111.843 113.863 139.257 1.00 62.22  ? 299 LEU D CD1 1 
ATOM   3407 C  CD2 . LEU B 2 299 ? 110.565 113.966 141.404 1.00 62.22  ? 299 LEU D CD2 1 
ATOM   3408 N  N   . THR B 2 300 ? 116.511 113.761 142.525 1.00 72.60  ? 300 THR D N   1 
ATOM   3409 C  CA  . THR B 2 300 ? 117.429 113.243 143.526 1.00 72.60  ? 300 THR D CA  1 
ATOM   3410 C  C   . THR B 2 300 ? 117.043 113.744 144.916 1.00 72.60  ? 300 THR D C   1 
ATOM   3411 O  O   . THR B 2 300 ? 116.277 114.698 145.075 1.00 72.60  ? 300 THR D O   1 
ATOM   3412 C  CB  . THR B 2 300 ? 118.866 113.650 143.202 1.00 72.60  ? 300 THR D CB  1 
ATOM   3413 O  OG1 . THR B 2 300 ? 118.893 115.019 142.778 1.00 72.60  ? 300 THR D OG1 1 
ATOM   3414 C  CG2 . THR B 2 300 ? 119.431 112.773 142.096 1.00 72.60  ? 300 THR D CG2 1 
ATOM   3415 N  N   . ASP B 2 301 ? 117.586 113.079 145.930 1.00 90.64  ? 301 ASP D N   1 
ATOM   3416 C  CA  . ASP B 2 301 ? 117.312 113.416 147.328 1.00 90.64  ? 301 ASP D CA  1 
ATOM   3417 C  C   . ASP B 2 301 ? 118.335 114.403 147.885 1.00 90.64  ? 301 ASP D C   1 
ATOM   3418 O  O   . ASP B 2 301 ? 118.966 114.167 148.913 1.00 90.64  ? 301 ASP D O   1 
ATOM   3419 C  CB  . ASP B 2 301 ? 117.265 112.142 148.162 1.00 90.64  ? 301 ASP D CB  1 
ATOM   3420 C  CG  . ASP B 2 301 ? 118.524 111.304 148.023 1.00 90.64  ? 301 ASP D CG  1 
ATOM   3421 O  OD1 . ASP B 2 301 ? 119.337 111.588 147.118 1.00 90.64  ? 301 ASP D OD1 1 
ATOM   3422 O  OD2 . ASP B 2 301 ? 118.699 110.358 148.818 1.00 90.64  ? 301 ASP D OD2 1 
ATOM   3423 N  N   . GLY B 2 302 ? 118.505 115.530 147.196 1.00 92.07  ? 302 GLY D N   1 
ATOM   3424 C  CA  . GLY B 2 302 ? 119.488 116.516 147.584 1.00 92.07  ? 302 GLY D CA  1 
ATOM   3425 C  C   . GLY B 2 302 ? 120.893 116.234 147.104 1.00 92.07  ? 302 GLY D C   1 
ATOM   3426 O  O   . GLY B 2 302 ? 121.743 117.132 147.166 1.00 92.07  ? 302 GLY D O   1 
ATOM   3427 N  N   . GLU B 2 303 ? 121.168 115.023 146.633 1.00 101.95 ? 303 GLU D N   1 
ATOM   3428 C  CA  . GLU B 2 303 ? 122.474 114.716 146.073 1.00 101.95 ? 303 GLU D CA  1 
ATOM   3429 C  C   . GLU B 2 303 ? 122.574 115.344 144.683 1.00 101.95 ? 303 GLU D C   1 
ATOM   3430 O  O   . GLU B 2 303 ? 121.779 115.010 143.796 1.00 101.95 ? 303 GLU D O   1 
ATOM   3431 C  CB  . GLU B 2 303 ? 122.652 113.195 146.001 1.00 101.95 ? 303 GLU D CB  1 
ATOM   3432 C  CG  . GLU B 2 303 ? 123.733 112.638 145.075 1.00 101.95 ? 303 GLU D CG  1 
ATOM   3433 C  CD  . GLU B 2 303 ? 125.118 113.189 145.354 1.00 101.95 ? 303 GLU D CD  1 
ATOM   3434 O  OE1 . GLU B 2 303 ? 125.559 114.097 144.622 1.00 101.95 ? 303 GLU D OE1 1 
ATOM   3435 O  OE2 . GLU B 2 303 ? 125.763 112.718 146.316 1.00 101.95 ? 303 GLU D OE2 1 
ATOM   3436 N  N   . PRO B 2 304 ? 123.514 116.264 144.462 1.00 96.90  ? 304 PRO D N   1 
ATOM   3437 C  CA  . PRO B 2 304 ? 123.613 116.912 143.145 1.00 96.90  ? 304 PRO D CA  1 
ATOM   3438 C  C   . PRO B 2 304 ? 123.841 115.901 142.029 1.00 96.90  ? 304 PRO D C   1 
ATOM   3439 O  O   . PRO B 2 304 ? 124.650 114.979 142.152 1.00 96.90  ? 304 PRO D O   1 
ATOM   3440 C  CB  . PRO B 2 304 ? 124.797 117.872 143.311 1.00 96.90  ? 304 PRO D CB  1 
ATOM   3441 C  CG  . PRO B 2 304 ? 125.563 117.354 144.493 1.00 96.90  ? 304 PRO D CG  1 
ATOM   3442 C  CD  . PRO B 2 304 ? 124.520 116.777 145.406 1.00 96.90  ? 304 PRO D CD  1 
ATOM   3443 N  N   . LEU B 2 305 ? 123.116 116.088 140.929 1.00 79.24  ? 305 LEU D N   1 
ATOM   3444 C  CA  . LEU B 2 305 ? 123.043 115.066 139.896 1.00 79.24  ? 305 LEU D CA  1 
ATOM   3445 C  C   . LEU B 2 305 ? 124.348 114.971 139.115 1.00 79.24  ? 305 LEU D C   1 
ATOM   3446 O  O   . LEU B 2 305 ? 125.180 115.882 139.127 1.00 79.24  ? 305 LEU D O   1 
ATOM   3447 C  CB  . LEU B 2 305 ? 121.883 115.354 138.943 1.00 79.24  ? 305 LEU D CB  1 
ATOM   3448 C  CG  . LEU B 2 305 ? 122.018 116.561 138.018 1.00 79.24  ? 305 LEU D CG  1 
ATOM   3449 C  CD1 . LEU B 2 305 ? 122.330 116.123 136.593 1.00 79.24  ? 305 LEU D CD1 1 
ATOM   3450 C  CD2 . LEU B 2 305 ? 120.748 117.387 138.071 1.00 79.24  ? 305 LEU D CD2 1 
ATOM   3451 N  N   . ASP B 2 306 ? 124.518 113.842 138.433 1.00 66.08  ? 306 ASP D N   1 
ATOM   3452 C  CA  . ASP B 2 306 ? 125.696 113.573 137.619 1.00 66.08  ? 306 ASP D CA  1 
ATOM   3453 C  C   . ASP B 2 306 ? 125.319 113.725 136.151 1.00 66.08  ? 306 ASP D C   1 
ATOM   3454 O  O   . ASP B 2 306 ? 124.303 113.178 135.707 1.00 66.08  ? 306 ASP D O   1 
ATOM   3455 C  CB  . ASP B 2 306 ? 126.241 112.173 137.899 1.00 66.08  ? 306 ASP D CB  1 
ATOM   3456 C  CG  . ASP B 2 306 ? 127.679 112.005 137.451 1.00 66.08  ? 306 ASP D CG  1 
ATOM   3457 O  OD1 . ASP B 2 306 ? 128.184 112.884 136.722 1.00 66.08  ? 306 ASP D OD1 1 
ATOM   3458 O  OD2 . ASP B 2 306 ? 128.304 110.992 137.829 1.00 66.08  ? 306 ASP D OD2 1 
ATOM   3459 N  N   . LYS B 2 307 ? 126.133 114.472 135.403 1.00 60.41  ? 307 LYS D N   1 
ATOM   3460 C  CA  . LYS B 2 307 ? 125.823 114.721 134.000 1.00 60.41  ? 307 LYS D CA  1 
ATOM   3461 C  C   . LYS B 2 307 ? 126.058 113.486 133.141 1.00 60.41  ? 307 LYS D C   1 
ATOM   3462 O  O   . LYS B 2 307 ? 125.411 113.323 132.100 1.00 60.41  ? 307 LYS D O   1 
ATOM   3463 C  CB  . LYS B 2 307 ? 126.655 115.893 133.480 1.00 60.41  ? 307 LYS D CB  1 
ATOM   3464 C  CG  . LYS B 2 307 ? 126.726 117.078 134.432 1.00 60.41  ? 307 LYS D CG  1 
ATOM   3465 C  CD  . LYS B 2 307 ? 125.369 117.740 134.594 1.00 60.41  ? 307 LYS D CD  1 
ATOM   3466 C  CE  . LYS B 2 307 ? 124.973 118.497 133.340 1.00 60.41  ? 307 LYS D CE  1 
ATOM   3467 N  NZ  . LYS B 2 307 ? 125.877 119.652 133.083 1.00 60.41  ? 307 LYS D NZ  1 
ATOM   3468 N  N   . THR B 2 308 ? 126.977 112.609 133.552 1.00 55.43  ? 308 THR D N   1 
ATOM   3469 C  CA  . THR B 2 308 ? 127.342 111.474 132.710 1.00 55.43  ? 308 THR D CA  1 
ATOM   3470 C  C   . THR B 2 308 ? 126.205 110.464 132.594 1.00 55.43  ? 308 THR D C   1 
ATOM   3471 O  O   . THR B 2 308 ? 125.864 110.036 131.486 1.00 55.43  ? 308 THR D O   1 
ATOM   3472 C  CB  . THR B 2 308 ? 128.598 110.797 133.255 1.00 55.43  ? 308 THR D CB  1 
ATOM   3473 O  OG1 . THR B 2 308 ? 128.305 110.192 134.520 1.00 55.43  ? 308 THR D OG1 1 
ATOM   3474 C  CG2 . THR B 2 308 ? 129.714 111.815 133.432 1.00 55.43  ? 308 THR D CG2 1 
ATOM   3475 N  N   . GLU B 2 309 ? 125.608 110.071 133.722 1.00 52.97  ? 309 GLU D N   1 
ATOM   3476 C  CA  . GLU B 2 309 ? 124.578 109.036 133.692 1.00 52.97  ? 309 GLU D CA  1 
ATOM   3477 C  C   . GLU B 2 309 ? 123.360 109.485 132.894 1.00 52.97  ? 309 GLU D C   1 
ATOM   3478 O  O   . GLU B 2 309 ? 122.810 108.715 132.093 1.00 52.97  ? 309 GLU D O   1 
ATOM   3479 C  CB  . GLU B 2 309 ? 124.181 108.658 135.118 1.00 52.97  ? 309 GLU D CB  1 
ATOM   3480 C  CG  . GLU B 2 309 ? 125.318 108.059 135.928 1.00 52.97  ? 309 GLU D CG  1 
ATOM   3481 C  CD  . GLU B 2 309 ? 124.902 107.688 137.336 1.00 52.97  ? 309 GLU D CD  1 
ATOM   3482 O  OE1 . GLU B 2 309 ? 123.826 108.142 137.777 1.00 52.97  ? 309 GLU D OE1 1 
ATOM   3483 O  OE2 . GLU B 2 309 ? 125.652 106.945 138.002 1.00 52.97  ? 309 GLU D OE2 1 
ATOM   3484 N  N   . TRP B 2 310 ? 122.929 110.732 133.094 1.00 36.93  ? 310 TRP D N   1 
ATOM   3485 C  CA  . TRP B 2 310 ? 121.823 111.266 132.309 1.00 36.93  ? 310 TRP D CA  1 
ATOM   3486 C  C   . TRP B 2 310 ? 122.165 111.269 130.827 1.00 36.93  ? 310 TRP D C   1 
ATOM   3487 O  O   . TRP B 2 310 ? 121.335 110.902 129.986 1.00 36.93  ? 310 TRP D O   1 
ATOM   3488 C  CB  . TRP B 2 310 ? 121.480 112.675 132.787 1.00 36.93  ? 310 TRP D CB  1 
ATOM   3489 C  CG  . TRP B 2 310 ? 120.179 113.190 132.274 1.00 36.93  ? 310 TRP D CG  1 
ATOM   3490 C  CD1 . TRP B 2 310 ? 119.217 112.481 131.621 1.00 36.93  ? 310 TRP D CD1 1 
ATOM   3491 C  CD2 . TRP B 2 310 ? 119.694 114.534 132.367 1.00 36.93  ? 310 TRP D CD2 1 
ATOM   3492 N  NE1 . TRP B 2 310 ? 118.161 113.299 131.302 1.00 36.93  ? 310 TRP D NE1 1 
ATOM   3493 C  CE2 . TRP B 2 310 ? 118.430 114.565 131.750 1.00 36.93  ? 310 TRP D CE2 1 
ATOM   3494 C  CE3 . TRP B 2 310 ? 120.206 115.714 132.914 1.00 36.93  ? 310 TRP D CE3 1 
ATOM   3495 C  CZ2 . TRP B 2 310 ? 117.671 115.728 131.663 1.00 36.93  ? 310 TRP D CZ2 1 
ATOM   3496 C  CZ3 . TRP B 2 310 ? 119.451 116.867 132.827 1.00 36.93  ? 310 TRP D CZ3 1 
ATOM   3497 C  CH2 . TRP B 2 310 ? 118.198 116.866 132.207 1.00 36.93  ? 310 TRP D CH2 1 
ATOM   3498 N  N   . GLN B 2 311 ? 123.393 111.668 130.490 1.00 37.25  ? 311 GLN D N   1 
ATOM   3499 C  CA  . GLN B 2 311 ? 123.832 111.614 129.102 1.00 37.25  ? 311 GLN D CA  1 
ATOM   3500 C  C   . GLN B 2 311 ? 123.885 110.182 128.588 1.00 37.25  ? 311 GLN D C   1 
ATOM   3501 O  O   . GLN B 2 311 ? 123.564 109.938 127.422 1.00 37.25  ? 311 GLN D O   1 
ATOM   3502 C  CB  . GLN B 2 311 ? 125.197 112.284 128.954 1.00 37.25  ? 311 GLN D CB  1 
ATOM   3503 C  CG  . GLN B 2 311 ? 125.571 112.604 127.520 1.00 37.25  ? 311 GLN D CG  1 
ATOM   3504 C  CD  . GLN B 2 311 ? 124.574 113.530 126.853 1.00 37.25  ? 311 GLN D CD  1 
ATOM   3505 O  OE1 . GLN B 2 311 ? 124.028 114.434 127.486 1.00 37.25  ? 311 GLN D OE1 1 
ATOM   3506 N  NE2 . GLN B 2 311 ? 124.331 113.310 125.566 1.00 37.25  ? 311 GLN D NE2 1 
ATOM   3507 N  N   . GLN B 2 312 ? 124.285 109.229 129.434 1.00 36.80  ? 312 GLN D N   1 
ATOM   3508 C  CA  . GLN B 2 312 ? 124.288 107.827 129.024 1.00 36.80  ? 312 GLN D CA  1 
ATOM   3509 C  C   . GLN B 2 312 ? 122.889 107.370 128.633 1.00 36.80  ? 312 GLN D C   1 
ATOM   3510 O  O   . GLN B 2 312 ? 122.689 106.778 127.563 1.00 36.80  ? 312 GLN D O   1 
ATOM   3511 C  CB  . GLN B 2 312 ? 124.835 106.953 130.153 1.00 36.80  ? 312 GLN D CB  1 
ATOM   3512 C  CG  . GLN B 2 312 ? 126.326 107.078 130.387 1.00 36.80  ? 312 GLN D CG  1 
ATOM   3513 C  CD  . GLN B 2 312 ? 127.132 106.208 129.453 1.00 36.80  ? 312 GLN D CD  1 
ATOM   3514 O  OE1 . GLN B 2 312 ? 126.582 105.375 128.734 1.00 36.80  ? 312 GLN D OE1 1 
ATOM   3515 N  NE2 . GLN B 2 312 ? 128.446 106.393 129.458 1.00 36.80  ? 312 GLN D NE2 1 
ATOM   3516 N  N   . ILE B 2 313 ? 121.903 107.646 129.488 1.00 29.73  ? 313 ILE D N   1 
ATOM   3517 C  CA  . ILE B 2 313 ? 120.537 107.215 129.205 1.00 29.73  ? 313 ILE D CA  1 
ATOM   3518 C  C   . ILE B 2 313 ? 119.994 107.925 127.971 1.00 29.73  ? 313 ILE D C   1 
ATOM   3519 O  O   . ILE B 2 313 ? 119.324 107.311 127.128 1.00 29.73  ? 313 ILE D O   1 
ATOM   3520 C  CB  . ILE B 2 313 ? 119.644 107.437 130.439 1.00 29.73  ? 313 ILE D CB  1 
ATOM   3521 C  CG1 . ILE B 2 313 ? 119.739 106.232 131.373 1.00 29.73  ? 313 ILE D CG1 1 
ATOM   3522 C  CG2 . ILE B 2 313 ? 118.201 107.680 130.032 1.00 29.73  ? 313 ILE D CG2 1 
ATOM   3523 C  CD1 . ILE B 2 313 ? 118.984 106.402 132.664 1.00 29.73  ? 313 ILE D CD1 1 
ATOM   3524 N  N   . PHE B 2 314 ? 120.274 109.223 127.838 1.00 34.99  ? 314 PHE D N   1 
ATOM   3525 C  CA  . PHE B 2 314 ? 119.805 109.961 126.670 1.00 34.99  ? 314 PHE D CA  1 
ATOM   3526 C  C   . PHE B 2 314 ? 120.408 109.410 125.384 1.00 34.99  ? 314 PHE D C   1 
ATOM   3527 O  O   . PHE B 2 314 ? 119.707 109.266 124.376 1.00 34.99  ? 314 PHE D O   1 
ATOM   3528 C  CB  . PHE B 2 314 ? 120.137 111.442 126.827 1.00 34.99  ? 314 PHE D CB  1 
ATOM   3529 C  CG  . PHE B 2 314 ? 119.187 112.350 126.114 1.00 34.99  ? 314 PHE D CG  1 
ATOM   3530 C  CD1 . PHE B 2 314 ? 117.834 112.306 126.386 1.00 34.99  ? 314 PHE D CD1 1 
ATOM   3531 C  CD2 . PHE B 2 314 ? 119.647 113.251 125.173 1.00 34.99  ? 314 PHE D CD2 1 
ATOM   3532 C  CE1 . PHE B 2 314 ? 116.956 113.143 125.732 1.00 34.99  ? 314 PHE D CE1 1 
ATOM   3533 C  CE2 . PHE B 2 314 ? 118.775 114.089 124.516 1.00 34.99  ? 314 PHE D CE2 1 
ATOM   3534 C  CZ  . PHE B 2 314 ? 117.427 114.035 124.796 1.00 34.99  ? 314 PHE D CZ  1 
ATOM   3535 N  N   . ASP B 2 315 ? 121.706 109.098 125.399 1.00 34.61  ? 315 ASP D N   1 
ATOM   3536 C  CA  . ASP B 2 315 ? 122.347 108.519 124.225 1.00 34.61  ? 315 ASP D CA  1 
ATOM   3537 C  C   . ASP B 2 315 ? 121.753 107.159 123.892 1.00 34.61  ? 315 ASP D C   1 
ATOM   3538 O  O   . ASP B 2 315 ? 121.548 106.834 122.717 1.00 34.61  ? 315 ASP D O   1 
ATOM   3539 C  CB  . ASP B 2 315 ? 123.853 108.400 124.455 1.00 34.61  ? 315 ASP D CB  1 
ATOM   3540 C  CG  . ASP B 2 315 ? 124.567 109.727 124.323 1.00 34.61  ? 315 ASP D CG  1 
ATOM   3541 O  OD1 . ASP B 2 315 ? 123.917 110.716 123.926 1.00 34.61  ? 315 ASP D OD1 1 
ATOM   3542 O  OD2 . ASP B 2 315 ? 125.779 109.782 124.620 1.00 34.61  ? 315 ASP D OD2 1 
ATOM   3543 N  N   . ILE B 2 316 ? 121.475 106.347 124.914 1.00 34.70  ? 316 ILE D N   1 
ATOM   3544 C  CA  . ILE B 2 316 ? 120.883 105.034 124.671 1.00 34.70  ? 316 ILE D CA  1 
ATOM   3545 C  C   . ILE B 2 316 ? 119.512 105.178 124.024 1.00 34.70  ? 316 ILE D C   1 
ATOM   3546 O  O   . ILE B 2 316 ? 119.178 104.458 123.075 1.00 34.70  ? 316 ILE D O   1 
ATOM   3547 C  CB  . ILE B 2 316 ? 120.811 104.230 125.983 1.00 34.70  ? 316 ILE D CB  1 
ATOM   3548 C  CG1 . ILE B 2 316 ? 122.158 103.573 126.279 1.00 34.70  ? 316 ILE D CG1 1 
ATOM   3549 C  CG2 . ILE B 2 316 ? 119.720 103.177 125.913 1.00 34.70  ? 316 ILE D CG2 1 
ATOM   3550 C  CD1 . ILE B 2 316 ? 122.437 102.351 125.440 1.00 34.70  ? 316 ILE D CD1 1 
ATOM   3551 N  N   . MET B 2 317 ? 118.701 106.116 124.514 1.00 51.63  ? 317 MET D N   1 
ATOM   3552 C  CA  . MET B 2 317 ? 117.316 106.196 124.059 1.00 51.63  ? 317 MET D CA  1 
ATOM   3553 C  C   . MET B 2 317 ? 117.154 106.929 122.731 1.00 51.63  ? 317 MET D C   1 
ATOM   3554 O  O   . MET B 2 317 ? 116.255 106.586 121.957 1.00 51.63  ? 317 MET D O   1 
ATOM   3555 C  CB  . MET B 2 317 ? 116.452 106.869 125.124 1.00 51.63  ? 317 MET D CB  1 
ATOM   3556 C  CG  . MET B 2 317 ? 116.328 106.077 126.412 1.00 51.63  ? 317 MET D CG  1 
ATOM   3557 S  SD  . MET B 2 317 ? 115.093 104.772 126.312 1.00 51.63  ? 317 MET D SD  1 
ATOM   3558 C  CE  . MET B 2 317 ? 116.104 103.332 126.635 1.00 51.63  ? 317 MET D CE  1 
ATOM   3559 N  N   . TRP B 2 318 ? 117.987 107.932 122.439 1.00 51.63  ? 318 TRP D N   1 
ATOM   3560 C  CA  . TRP B 2 318 ? 117.700 108.845 121.338 1.00 51.63  ? 318 TRP D CA  1 
ATOM   3561 C  C   . TRP B 2 318 ? 118.688 108.810 120.177 1.00 51.63  ? 318 TRP D C   1 
ATOM   3562 O  O   . TRP B 2 318 ? 118.531 109.607 119.246 1.00 51.63  ? 318 TRP D O   1 
ATOM   3563 C  CB  . TRP B 2 318 ? 117.624 110.290 121.856 1.00 51.63  ? 318 TRP D CB  1 
ATOM   3564 C  CG  . TRP B 2 318 ? 116.309 110.654 122.471 1.00 51.63  ? 318 TRP D CG  1 
ATOM   3565 C  CD1 . TRP B 2 318 ? 115.861 110.305 123.709 1.00 51.63  ? 318 TRP D CD1 1 
ATOM   3566 C  CD2 . TRP B 2 318 ? 115.278 111.452 121.881 1.00 51.63  ? 318 TRP D CD2 1 
ATOM   3567 N  NE1 . TRP B 2 318 ? 114.612 110.830 123.925 1.00 51.63  ? 318 TRP D NE1 1 
ATOM   3568 C  CE2 . TRP B 2 318 ? 114.231 111.539 122.817 1.00 51.63  ? 318 TRP D CE2 1 
ATOM   3569 C  CE3 . TRP B 2 318 ? 115.136 112.099 120.651 1.00 51.63  ? 318 TRP D CE3 1 
ATOM   3570 C  CZ2 . TRP B 2 318 ? 113.060 112.245 122.562 1.00 51.63  ? 318 TRP D CZ2 1 
ATOM   3571 C  CZ3 . TRP B 2 318 ? 113.973 112.799 120.401 1.00 51.63  ? 318 TRP D CZ3 1 
ATOM   3572 C  CH2 . TRP B 2 318 ? 112.951 112.867 121.351 1.00 51.63  ? 318 TRP D CH2 1 
ATOM   3573 N  N   . SER B 2 319 ? 119.686 107.931 120.189 1.00 32.34  ? 319 SER D N   1 
ATOM   3574 C  CA  . SER B 2 319 ? 120.689 107.953 119.133 1.00 32.34  ? 319 SER D CA  1 
ATOM   3575 C  C   . SER B 2 319 ? 120.122 107.404 117.825 1.00 32.34  ? 319 SER D C   1 
ATOM   3576 O  O   . SER B 2 319 ? 119.108 106.703 117.798 1.00 32.34  ? 319 SER D O   1 
ATOM   3577 C  CB  . SER B 2 319 ? 121.922 107.152 119.545 1.00 32.34  ? 319 SER D CB  1 
ATOM   3578 O  OG  . SER B 2 319 ? 121.580 105.816 119.860 1.00 32.34  ? 319 SER D OG  1 
ATOM   3579 N  N   . ASP B 2 320 ? 120.797 107.738 116.728 1.00 33.64  ? 320 ASP D N   1 
ATOM   3580 C  CA  . ASP B 2 320 ? 120.422 107.315 115.387 1.00 33.64  ? 320 ASP D CA  1 
ATOM   3581 C  C   . ASP B 2 320 ? 121.671 106.916 114.615 1.00 33.64  ? 320 ASP D C   1 
ATOM   3582 O  O   . ASP B 2 320 ? 122.756 107.449 114.871 1.00 33.64  ? 320 ASP D O   1 
ATOM   3583 C  CB  . ASP B 2 320 ? 119.689 108.431 114.627 1.00 33.64  ? 320 ASP D CB  1 
ATOM   3584 C  CG  . ASP B 2 320 ? 118.186 108.276 114.671 1.00 33.64  ? 320 ASP D CG  1 
ATOM   3585 O  OD1 . ASP B 2 320 ? 117.702 107.141 114.488 1.00 33.64  ? 320 ASP D OD1 1 
ATOM   3586 O  OD2 . ASP B 2 320 ? 117.487 109.289 114.883 1.00 33.64  ? 320 ASP D OD2 1 
ATOM   3587 N  N   . PRO B 2 321 ? 121.549 105.990 113.666 1.00 32.18  ? 321 PRO D N   1 
ATOM   3588 C  CA  . PRO B 2 321 ? 122.717 105.587 112.879 1.00 32.18  ? 321 PRO D CA  1 
ATOM   3589 C  C   . PRO B 2 321 ? 122.893 106.451 111.641 1.00 32.18  ? 321 PRO D C   1 
ATOM   3590 O  O   . PRO B 2 321 ? 121.944 107.045 111.126 1.00 32.18  ? 321 PRO D O   1 
ATOM   3591 C  CB  . PRO B 2 321 ? 122.394 104.141 112.500 1.00 32.18  ? 321 PRO D CB  1 
ATOM   3592 C  CG  . PRO B 2 321 ? 120.914 104.156 112.350 1.00 32.18  ? 321 PRO D CG  1 
ATOM   3593 C  CD  . PRO B 2 321 ? 120.388 105.128 113.389 1.00 32.18  ? 321 PRO D CD  1 
ATOM   3594 N  N   . GLN B 2 322 ? 124.134 106.508 111.161 1.00 35.70  ? 322 GLN D N   1 
ATOM   3595 C  CA  . GLN B 2 322 ? 124.477 107.249 109.957 1.00 35.70  ? 322 GLN D CA  1 
ATOM   3596 C  C   . GLN B 2 322 ? 125.467 106.446 109.127 1.00 35.70  ? 322 GLN D C   1 
ATOM   3597 O  O   . GLN B 2 322 ? 126.205 105.607 109.650 1.00 35.70  ? 322 GLN D O   1 
ATOM   3598 C  CB  . GLN B 2 322 ? 125.066 108.628 110.288 1.00 35.70  ? 322 GLN D CB  1 
ATOM   3599 C  CG  . GLN B 2 322 ? 126.398 108.582 111.019 1.00 35.70  ? 322 GLN D CG  1 
ATOM   3600 C  CD  . GLN B 2 322 ? 127.125 109.912 110.985 1.00 35.70  ? 322 GLN D CD  1 
ATOM   3601 O  OE1 . GLN B 2 322 ? 126.502 110.972 110.950 1.00 35.70  ? 322 GLN D OE1 1 
ATOM   3602 N  NE2 . GLN B 2 322 ? 128.452 109.862 110.996 1.00 35.70  ? 322 GLN D NE2 1 
ATOM   3603 N  N   . ALA B 2 323 ? 125.470 106.710 107.819 1.00 36.74  ? 323 ALA D N   1 
ATOM   3604 C  CA  . ALA B 2 323 ? 126.345 105.970 106.915 1.00 36.74  ? 323 ALA D CA  1 
ATOM   3605 C  C   . ALA B 2 323 ? 127.795 106.421 107.040 1.00 36.74  ? 323 ALA D C   1 
ATOM   3606 O  O   . ALA B 2 323 ? 128.712 105.592 107.011 1.00 36.74  ? 323 ALA D O   1 
ATOM   3607 C  CB  . ALA B 2 323 ? 125.858 106.121 105.475 1.00 36.74  ? 323 ALA D CB  1 
ATOM   3608 N  N   . THR B 2 324 ? 128.024 107.724 107.176 1.00 40.93  ? 324 THR D N   1 
ATOM   3609 C  CA  . THR B 2 324 ? 129.379 108.253 107.205 1.00 40.93  ? 324 THR D CA  1 
ATOM   3610 C  C   . THR B 2 324 ? 130.073 107.904 108.520 1.00 40.93  ? 324 THR D C   1 
ATOM   3611 O  O   . THR B 2 324 ? 129.444 107.499 109.502 1.00 40.93  ? 324 THR D O   1 
ATOM   3612 C  CB  . THR B 2 324 ? 129.369 109.769 107.009 1.00 40.93  ? 324 THR D CB  1 
ATOM   3613 O  OG1 . THR B 2 324 ? 128.508 110.373 107.981 1.00 40.93  ? 324 THR D OG1 1 
ATOM   3614 C  CG2 . THR B 2 324 ? 128.873 110.120 105.616 1.00 40.93  ? 324 THR D CG2 1 
ATOM   3615 N  N   . MET B 2 325 ? 131.394 108.066 108.526 1.00 40.32  ? 325 MET D N   1 
ATOM   3616 C  CA  . MET B 2 325 ? 132.194 107.713 109.687 1.00 40.32  ? 325 MET D CA  1 
ATOM   3617 C  C   . MET B 2 325 ? 132.100 108.796 110.761 1.00 40.32  ? 325 MET D C   1 
ATOM   3618 O  O   . MET B 2 325 ? 131.571 109.890 110.545 1.00 40.32  ? 325 MET D O   1 
ATOM   3619 C  CB  . MET B 2 325 ? 133.653 107.499 109.286 1.00 40.32  ? 325 MET D CB  1 
ATOM   3620 C  CG  . MET B 2 325 ? 133.842 106.834 107.935 1.00 40.32  ? 325 MET D CG  1 
ATOM   3621 S  SD  . MET B 2 325 ? 133.282 105.123 107.913 1.00 40.32  ? 325 MET D SD  1 
ATOM   3622 C  CE  . MET B 2 325 ? 133.304 104.780 106.155 1.00 40.32  ? 325 MET D CE  1 
ATOM   3623 N  N   . GLY B 2 326 ? 132.628 108.472 111.939 1.00 40.06  ? 326 GLY D N   1 
ATOM   3624 C  CA  . GLY B 2 326 ? 132.692 109.416 113.033 1.00 40.06  ? 326 GLY D CA  1 
ATOM   3625 C  C   . GLY B 2 326 ? 131.406 109.488 113.834 1.00 40.06  ? 326 GLY D C   1 
ATOM   3626 O  O   . GLY B 2 326 ? 130.343 109.007 113.428 1.00 40.06  ? 326 GLY D O   1 
ATOM   3627 N  N   . CYS B 2 327 ? 131.519 110.115 115.004 1.00 36.83  ? 327 CYS D N   1 
ATOM   3628 C  CA  . CYS B 2 327 ? 130.381 110.330 115.888 1.00 36.83  ? 327 CYS D CA  1 
ATOM   3629 C  C   . CYS B 2 327 ? 130.180 111.825 116.073 1.00 36.83  ? 327 CYS D C   1 
ATOM   3630 O  O   . CYS B 2 327 ? 131.044 112.508 116.629 1.00 36.83  ? 327 CYS D O   1 
ATOM   3631 C  CB  . CYS B 2 327 ? 130.587 109.651 117.245 1.00 36.83  ? 327 CYS D CB  1 
ATOM   3632 S  SG  . CYS B 2 327 ? 129.310 110.026 118.462 1.00 36.83  ? 327 CYS D SG  1 
ATOM   3633 N  N   . VAL B 2 328 ? 129.040 112.324 115.611 1.00 30.85  ? 328 VAL D N   1 
ATOM   3634 C  CA  . VAL B 2 328 ? 128.718 113.748 115.638 1.00 30.85  ? 328 VAL D CA  1 
ATOM   3635 C  C   . VAL B 2 328 ? 127.361 113.885 116.322 1.00 30.85  ? 328 VAL D C   1 
ATOM   3636 O  O   . VAL B 2 328 ? 126.615 112.896 116.398 1.00 30.85  ? 328 VAL D O   1 
ATOM   3637 C  CB  . VAL B 2 328 ? 128.717 114.346 114.219 1.00 30.85  ? 328 VAL D CB  1 
ATOM   3638 C  CG1 . VAL B 2 328 ? 129.905 113.845 113.417 1.00 30.85  ? 328 VAL D CG1 1 
ATOM   3639 C  CG2 . VAL B 2 328 ? 127.411 114.028 113.504 1.00 30.85  ? 328 VAL D CG2 1 
ATOM   3640 N  N   . PRO B 2 329 ? 126.994 115.053 116.850 1.00 30.50  ? 329 PRO D N   1 
ATOM   3641 C  CA  . PRO B 2 329 ? 125.707 115.153 117.533 1.00 30.50  ? 329 PRO D CA  1 
ATOM   3642 C  C   . PRO B 2 329 ? 124.512 115.320 116.597 1.00 30.50  ? 329 PRO D C   1 
ATOM   3643 O  O   . PRO B 2 329 ? 124.503 116.133 115.670 1.00 30.50  ? 329 PRO D O   1 
ATOM   3644 C  CB  . PRO B 2 329 ? 125.934 116.359 118.453 1.00 30.50  ? 329 PRO D CB  1 
ATOM   3645 C  CG  . PRO B 2 329 ? 127.062 117.179 117.669 1.00 30.50  ? 329 PRO D CG  1 
ATOM   3646 C  CD  . PRO B 2 329 ? 127.203 116.425 116.367 1.00 30.50  ? 329 PRO D CD  1 
ATOM   3647 N  N   . ASN B 2 330 ? 123.471 114.542 116.882 1.00 34.15  ? 330 ASN D N   1 
ATOM   3648 C  CA  . ASN B 2 330 ? 122.366 114.309 115.953 1.00 34.15  ? 330 ASN D CA  1 
ATOM   3649 C  C   . ASN B 2 330 ? 121.493 115.558 115.882 1.00 34.15  ? 330 ASN D C   1 
ATOM   3650 O  O   . ASN B 2 330 ? 120.527 115.735 116.626 1.00 34.15  ? 330 ASN D O   1 
ATOM   3651 C  CB  . ASN B 2 330 ? 121.569 113.086 116.393 1.00 34.15  ? 330 ASN D CB  1 
ATOM   3652 C  CG  . ASN B 2 330 ? 120.465 112.727 115.429 1.00 34.15  ? 330 ASN D CG  1 
ATOM   3653 O  OD1 . ASN B 2 330 ? 120.706 112.517 114.244 1.00 34.15  ? 330 ASN D OD1 1 
ATOM   3654 N  ND2 . ASN B 2 330 ? 119.247 112.626 115.940 1.00 34.15  ? 330 ASN D ND2 1 
ATOM   3655 N  N   . THR B 2 331 ? 121.857 116.446 114.954 1.00 36.94  ? 331 THR D N   1 
ATOM   3656 C  CA  . THR B 2 331 ? 121.136 117.703 114.793 1.00 36.94  ? 331 THR D CA  1 
ATOM   3657 C  C   . THR B 2 331 ? 119.848 117.533 114.001 1.00 36.94  ? 331 THR D C   1 
ATOM   3658 O  O   . THR B 2 331 ? 119.012 118.443 113.998 1.00 36.94  ? 331 THR D O   1 
ATOM   3659 C  CB  . THR B 2 331 ? 122.025 118.741 114.104 1.00 36.94  ? 331 THR D CB  1 
ATOM   3660 O  OG1 . THR B 2 331 ? 121.333 119.994 114.038 1.00 36.94  ? 331 THR D OG1 1 
ATOM   3661 C  CG2 . THR B 2 331 ? 122.380 118.290 112.691 1.00 36.94  ? 331 THR D CG2 1 
ATOM   3662 N  N   . LEU B 2 332 ? 119.673 116.402 113.318 1.00 34.30  ? 332 LEU D N   1 
ATOM   3663 C  CA  . LEU B 2 332 ? 118.455 116.185 112.546 1.00 34.30  ? 332 LEU D CA  1 
ATOM   3664 C  C   . LEU B 2 332 ? 117.245 116.013 113.457 1.00 34.30  ? 332 LEU D C   1 
ATOM   3665 O  O   . LEU B 2 332 ? 116.199 116.631 113.236 1.00 34.30  ? 332 LEU D O   1 
ATOM   3666 C  CB  . LEU B 2 332 ? 118.621 114.967 111.635 1.00 34.30  ? 332 LEU D CB  1 
ATOM   3667 C  CG  . LEU B 2 332 ? 117.462 114.659 110.686 1.00 34.30  ? 332 LEU D CG  1 
ATOM   3668 C  CD1 . LEU B 2 332 ? 117.200 115.837 109.765 1.00 34.30  ? 332 LEU D CD1 1 
ATOM   3669 C  CD2 . LEU B 2 332 ? 117.756 113.405 109.882 1.00 34.30  ? 332 LEU D CD2 1 
ATOM   3670 N  N   . ARG B 2 333 ? 117.374 115.181 114.489 1.00 31.32  ? 333 ARG D N   1 
ATOM   3671 C  CA  . ARG B 2 333 ? 116.289 114.970 115.440 1.00 31.32  ? 333 ARG D CA  1 
ATOM   3672 C  C   . ARG B 2 333 ? 116.389 115.883 116.652 1.00 31.32  ? 333 ARG D C   1 
ATOM   3673 O  O   . ARG B 2 333 ? 115.506 115.853 117.516 1.00 31.32  ? 333 ARG D O   1 
ATOM   3674 C  CB  . ARG B 2 333 ? 116.270 113.509 115.899 1.00 31.32  ? 333 ARG D CB  1 
ATOM   3675 C  CG  . ARG B 2 333 ? 114.920 113.000 116.359 1.00 31.32  ? 333 ARG D CG  1 
ATOM   3676 C  CD  . ARG B 2 333 ? 115.069 111.684 117.101 1.00 31.32  ? 333 ARG D CD  1 
ATOM   3677 N  NE  . ARG B 2 333 ? 115.261 110.563 116.190 1.00 31.32  ? 333 ARG D NE  1 
ATOM   3678 C  CZ  . ARG B 2 333 ? 114.278 109.930 115.565 1.00 31.32  ? 333 ARG D CZ  1 
ATOM   3679 N  NH1 . ARG B 2 333 ? 113.014 110.283 115.729 1.00 31.32  ? 333 ARG D NH1 1 
ATOM   3680 N  NH2 . ARG B 2 333 ? 114.570 108.916 114.756 1.00 31.32  ? 333 ARG D NH2 1 
ATOM   3681 N  N   . GLY B 2 334 ? 117.447 116.681 116.745 1.00 33.49  ? 334 GLY D N   1 
ATOM   3682 C  CA  . GLY B 2 334 ? 117.611 117.605 117.845 1.00 33.49  ? 334 GLY D CA  1 
ATOM   3683 C  C   . GLY B 2 334 ? 118.100 116.993 119.135 1.00 33.49  ? 334 GLY D C   1 
ATOM   3684 O  O   . GLY B 2 334 ? 118.219 117.712 120.134 1.00 33.49  ? 334 GLY D O   1 
ATOM   3685 N  N   . ALA B 2 335 ? 118.391 115.696 119.150 1.00 35.02  ? 335 ALA D N   1 
ATOM   3686 C  CA  . ALA B 2 335 ? 118.837 115.022 120.358 1.00 35.02  ? 335 ALA D CA  1 
ATOM   3687 C  C   . ALA B 2 335 ? 119.574 113.750 119.974 1.00 35.02  ? 335 ALA D C   1 
ATOM   3688 O  O   . ALA B 2 335 ? 119.442 113.254 118.852 1.00 35.02  ? 335 ALA D O   1 
ATOM   3689 C  CB  . ALA B 2 335 ? 117.661 114.699 121.284 1.00 35.02  ? 335 ALA D CB  1 
ATOM   3690 N  N   . GLY B 2 336 ? 120.354 113.227 120.914 1.00 36.62  ? 336 GLY D N   1 
ATOM   3691 C  CA  . GLY B 2 336 ? 121.108 112.015 120.666 1.00 36.62  ? 336 GLY D CA  1 
ATOM   3692 C  C   . GLY B 2 336 ? 122.319 112.255 119.792 1.00 36.62  ? 336 GLY D C   1 
ATOM   3693 O  O   . GLY B 2 336 ? 122.626 113.401 119.454 1.00 36.62  ? 336 GLY D O   1 
ATOM   3694 N  N   . VAL B 2 337 ? 123.018 111.188 119.421 1.00 32.88  ? 337 VAL D N   1 
ATOM   3695 C  CA  . VAL B 2 337 ? 124.222 111.298 118.606 1.00 32.88  ? 337 VAL D CA  1 
ATOM   3696 C  C   . VAL B 2 337 ? 124.125 110.348 117.421 1.00 32.88  ? 337 VAL D C   1 
ATOM   3697 O  O   . VAL B 2 337 ? 123.555 109.256 117.510 1.00 32.88  ? 337 VAL D O   1 
ATOM   3698 C  CB  . VAL B 2 337 ? 125.490 111.021 119.444 1.00 32.88  ? 337 VAL D CB  1 
ATOM   3699 C  CG1 . VAL B 2 337 ? 125.534 111.920 120.669 1.00 32.88  ? 337 VAL D CG1 1 
ATOM   3700 C  CG2 . VAL B 2 337 ? 125.552 109.562 119.856 1.00 32.88  ? 337 VAL D CG2 1 
ATOM   3701 N  N   . TRP B 2 338 ? 124.672 110.782 116.289 1.00 31.12  ? 338 TRP D N   1 
ATOM   3702 C  CA  . TRP B 2 338 ? 124.838 109.904 115.140 1.00 31.12  ? 338 TRP D CA  1 
ATOM   3703 C  C   . TRP B 2 338 ? 126.058 109.016 115.344 1.00 31.12  ? 338 TRP D C   1 
ATOM   3704 O  O   . TRP B 2 338 ? 127.112 109.479 115.787 1.00 31.12  ? 338 TRP D O   1 
ATOM   3705 C  CB  . TRP B 2 338 ? 125.000 110.720 113.857 1.00 31.12  ? 338 TRP D CB  1 
ATOM   3706 C  CG  . TRP B 2 338 ? 123.721 110.991 113.134 1.00 31.12  ? 338 TRP D CG  1 
ATOM   3707 C  CD1 . TRP B 2 338 ? 122.566 110.275 113.217 1.00 31.12  ? 338 TRP D CD1 1 
ATOM   3708 C  CD2 . TRP B 2 338 ? 123.470 112.052 112.205 1.00 31.12  ? 338 TRP D CD2 1 
ATOM   3709 N  NE1 . TRP B 2 338 ? 121.608 110.826 112.401 1.00 31.12  ? 338 TRP D NE1 1 
ATOM   3710 C  CE2 . TRP B 2 338 ? 122.140 111.917 111.767 1.00 31.12  ? 338 TRP D CE2 1 
ATOM   3711 C  CE3 . TRP B 2 338 ? 124.242 113.103 111.702 1.00 31.12  ? 338 TRP D CE3 1 
ATOM   3712 C  CZ2 . TRP B 2 338 ? 121.562 112.794 110.854 1.00 31.12  ? 338 TRP D CZ2 1 
ATOM   3713 C  CZ3 . TRP B 2 338 ? 123.667 113.972 110.794 1.00 31.12  ? 338 TRP D CZ3 1 
ATOM   3714 C  CH2 . TRP B 2 338 ? 122.340 113.812 110.380 1.00 31.12  ? 338 TRP D CH2 1 
ATOM   3715 N  N   . PHE B 2 339 ? 125.913 107.735 115.021 1.00 28.70  ? 339 PHE D N   1 
ATOM   3716 C  CA  . PHE B 2 339 ? 127.009 106.784 115.142 1.00 28.70  ? 339 PHE D CA  1 
ATOM   3717 C  C   . PHE B 2 339 ? 127.192 106.056 113.819 1.00 28.70  ? 339 PHE D C   1 
ATOM   3718 O  O   . PHE B 2 339 ? 126.218 105.586 113.223 1.00 28.70  ? 339 PHE D O   1 
ATOM   3719 C  CB  . PHE B 2 339 ? 126.764 105.795 116.292 1.00 28.70  ? 339 PHE D CB  1 
ATOM   3720 C  CG  . PHE B 2 339 ? 125.614 104.856 116.066 1.00 28.70  ? 339 PHE D CG  1 
ATOM   3721 C  CD1 . PHE B 2 339 ? 124.316 105.251 116.330 1.00 28.70  ? 339 PHE D CD1 1 
ATOM   3722 C  CD2 . PHE B 2 339 ? 125.835 103.567 115.616 1.00 28.70  ? 339 PHE D CD2 1 
ATOM   3723 C  CE1 . PHE B 2 339 ? 123.260 104.386 116.133 1.00 28.70  ? 339 PHE D CE1 1 
ATOM   3724 C  CE2 . PHE B 2 339 ? 124.783 102.698 115.417 1.00 28.70  ? 339 PHE D CE2 1 
ATOM   3725 C  CZ  . PHE B 2 339 ? 123.494 103.108 115.676 1.00 28.70  ? 339 PHE D CZ  1 
ATOM   3726 N  N   . GLY B 2 340 ? 128.438 105.983 113.354 1.00 37.25  ? 340 GLY D N   1 
ATOM   3727 C  CA  . GLY B 2 340 ? 128.754 105.346 112.098 1.00 37.25  ? 340 GLY D CA  1 
ATOM   3728 C  C   . GLY B 2 340 ? 129.276 103.933 112.267 1.00 37.25  ? 340 GLY D C   1 
ATOM   3729 O  O   . GLY B 2 340 ? 129.264 103.368 113.364 1.00 37.25  ? 340 GLY D O   1 
ATOM   3730 N  N   . PRO B 2 341 ? 129.733 103.327 111.170 1.00 37.41  ? 341 PRO D N   1 
ATOM   3731 C  CA  . PRO B 2 341 ? 130.258 101.954 111.253 1.00 37.41  ? 341 PRO D CA  1 
ATOM   3732 C  C   . PRO B 2 341 ? 131.481 101.811 112.143 1.00 37.41  ? 341 PRO D C   1 
ATOM   3733 O  O   . PRO B 2 341 ? 131.646 100.757 112.770 1.00 37.41  ? 341 PRO D O   1 
ATOM   3734 C  CB  . PRO B 2 341 ? 130.585 101.614 109.793 1.00 37.41  ? 341 PRO D CB  1 
ATOM   3735 C  CG  . PRO B 2 341 ? 130.757 102.934 109.126 1.00 37.41  ? 341 PRO D CG  1 
ATOM   3736 C  CD  . PRO B 2 341 ? 129.799 103.864 109.802 1.00 37.41  ? 341 PRO D CD  1 
ATOM   3737 N  N   . ASP B 2 342 ? 132.343 102.827 112.218 1.00 44.53  ? 342 ASP D N   1 
ATOM   3738 C  CA  . ASP B 2 342 ? 133.560 102.711 113.017 1.00 44.53  ? 342 ASP D CA  1 
ATOM   3739 C  C   . ASP B 2 342 ? 133.235 102.563 114.500 1.00 44.53  ? 342 ASP D C   1 
ATOM   3740 O  O   . ASP B 2 342 ? 133.736 101.650 115.170 1.00 44.53  ? 342 ASP D O   1 
ATOM   3741 C  CB  . ASP B 2 342 ? 134.455 103.928 112.780 1.00 44.53  ? 342 ASP D CB  1 
ATOM   3742 C  CG  . ASP B 2 342 ? 135.858 103.739 113.324 1.00 44.53  ? 342 ASP D CG  1 
ATOM   3743 O  OD1 . ASP B 2 342 ? 136.153 102.652 113.862 1.00 44.53  ? 342 ASP D OD1 1 
ATOM   3744 O  OD2 . ASP B 2 342 ? 136.669 104.682 113.211 1.00 44.53  ? 342 ASP D OD2 1 
ATOM   3745 N  N   . VAL B 2 343 ? 132.393 103.454 115.028 1.00 33.92  ? 343 VAL D N   1 
ATOM   3746 C  CA  . VAL B 2 343 ? 132.020 103.372 116.435 1.00 33.92  ? 343 VAL D CA  1 
ATOM   3747 C  C   . VAL B 2 343 ? 131.199 102.118 116.706 1.00 33.92  ? 343 VAL D C   1 
ATOM   3748 O  O   . VAL B 2 343 ? 131.319 101.515 117.778 1.00 33.92  ? 343 VAL D O   1 
ATOM   3749 C  CB  . VAL B 2 343 ? 131.283 104.654 116.866 1.00 33.92  ? 343 VAL D CB  1 
ATOM   3750 C  CG1 . VAL B 2 343 ? 130.134 104.938 115.938 1.00 33.92  ? 343 VAL D CG1 1 
ATOM   3751 C  CG2 . VAL B 2 343 ? 130.790 104.533 118.295 1.00 33.92  ? 343 VAL D CG2 1 
ATOM   3752 N  N   . THR B 2 344 ? 130.364 101.696 115.752 1.00 36.97  ? 344 THR D N   1 
ATOM   3753 C  CA  . THR B 2 344 ? 129.618 100.453 115.925 1.00 36.97  ? 344 THR D CA  1 
ATOM   3754 C  C   . THR B 2 344 ? 130.559 99.265  116.076 1.00 36.97  ? 344 THR D C   1 
ATOM   3755 O  O   . THR B 2 344 ? 130.389 98.436  116.980 1.00 36.97  ? 344 THR D O   1 
ATOM   3756 C  CB  . THR B 2 344 ? 128.674 100.237 114.740 1.00 36.97  ? 344 THR D CB  1 
ATOM   3757 O  OG1 . THR B 2 344 ? 127.504 101.047 114.903 1.00 36.97  ? 344 THR D OG1 1 
ATOM   3758 C  CG2 . THR B 2 344 ? 128.254 98.783  114.644 1.00 36.97  ? 344 THR D CG2 1 
ATOM   3759 N  N   . ASP B 2 345 ? 131.568 99.175  115.207 1.00 39.23  ? 345 ASP D N   1 
ATOM   3760 C  CA  . ASP B 2 345 ? 132.527 98.080  115.297 1.00 39.23  ? 345 ASP D CA  1 
ATOM   3761 C  C   . ASP B 2 345 ? 133.321 98.146  116.594 1.00 39.23  ? 345 ASP D C   1 
ATOM   3762 O  O   . ASP B 2 345 ? 133.562 97.115  117.233 1.00 39.23  ? 345 ASP D O   1 
ATOM   3763 C  CB  . ASP B 2 345 ? 133.464 98.103  114.092 1.00 39.23  ? 345 ASP D CB  1 
ATOM   3764 C  CG  . ASP B 2 345 ? 133.887 96.716  113.658 1.00 39.23  ? 345 ASP D CG  1 
ATOM   3765 O  OD1 . ASP B 2 345 ? 134.182 95.881  114.539 1.00 39.23  ? 345 ASP D OD1 1 
ATOM   3766 O  OD2 . ASP B 2 345 ? 133.924 96.459  112.437 1.00 39.23  ? 345 ASP D OD2 1 
ATOM   3767 N  N   . ASN B 2 346 ? 133.736 99.349  117.000 1.00 39.83  ? 346 ASN D N   1 
ATOM   3768 C  CA  . ASN B 2 346 ? 134.486 99.488  118.246 1.00 39.83  ? 346 ASN D CA  1 
ATOM   3769 C  C   . ASN B 2 346 ? 133.646 99.061  119.445 1.00 39.83  ? 346 ASN D C   1 
ATOM   3770 O  O   . ASN B 2 346 ? 134.134 98.362  120.339 1.00 39.83  ? 346 ASN D O   1 
ATOM   3771 C  CB  . ASN B 2 346 ? 134.970 100.928 118.409 1.00 39.83  ? 346 ASN D CB  1 
ATOM   3772 C  CG  . ASN B 2 346 ? 136.290 101.179 117.714 1.00 39.83  ? 346 ASN D CG  1 
ATOM   3773 O  OD1 . ASN B 2 346 ? 137.357 100.996 118.299 1.00 39.83  ? 346 ASN D OD1 1 
ATOM   3774 N  ND2 . ASN B 2 346 ? 136.226 101.600 116.456 1.00 39.83  ? 346 ASN D ND2 1 
ATOM   3775 N  N   . PHE B 2 347 ? 132.377 99.471  119.475 1.00 34.75  ? 347 PHE D N   1 
ATOM   3776 C  CA  . PHE B 2 347 ? 131.484 99.099  120.567 1.00 34.75  ? 347 PHE D CA  1 
ATOM   3777 C  C   . PHE B 2 347 ? 131.261 97.592  120.610 1.00 34.75  ? 347 PHE D C   1 
ATOM   3778 O  O   . PHE B 2 347 ? 131.305 96.978  121.685 1.00 34.75  ? 347 PHE D O   1 
ATOM   3779 C  CB  . PHE B 2 347 ? 130.160 99.847  120.406 1.00 34.75  ? 347 PHE D CB  1 
ATOM   3780 C  CG  . PHE B 2 347 ? 129.086 99.419  121.360 1.00 34.75  ? 347 PHE D CG  1 
ATOM   3781 C  CD1 . PHE B 2 347 ? 129.165 99.732  122.704 1.00 34.75  ? 347 PHE D CD1 1 
ATOM   3782 C  CD2 . PHE B 2 347 ? 127.980 98.724  120.905 1.00 34.75  ? 347 PHE D CD2 1 
ATOM   3783 C  CE1 . PHE B 2 347 ? 128.166 99.349  123.576 1.00 34.75  ? 347 PHE D CE1 1 
ATOM   3784 C  CE2 . PHE B 2 347 ? 126.982 98.337  121.774 1.00 34.75  ? 347 PHE D CE2 1 
ATOM   3785 C  CZ  . PHE B 2 347 ? 127.076 98.649  123.111 1.00 34.75  ? 347 PHE D CZ  1 
ATOM   3786 N  N   . LEU B 2 348 ? 131.033 96.977  119.446 1.00 35.34  ? 348 LEU D N   1 
ATOM   3787 C  CA  . LEU B 2 348 ? 130.826 95.534  119.402 1.00 35.34  ? 348 LEU D CA  1 
ATOM   3788 C  C   . LEU B 2 348 ? 132.070 94.783  119.858 1.00 35.34  ? 348 LEU D C   1 
ATOM   3789 O  O   . LEU B 2 348 ? 131.968 93.787  120.583 1.00 35.34  ? 348 LEU D O   1 
ATOM   3790 C  CB  . LEU B 2 348 ? 130.427 95.102  117.993 1.00 35.34  ? 348 LEU D CB  1 
ATOM   3791 C  CG  . LEU B 2 348 ? 128.969 95.343  117.606 1.00 35.34  ? 348 LEU D CG  1 
ATOM   3792 C  CD1 . LEU B 2 348 ? 128.843 95.529  116.106 1.00 35.34  ? 348 LEU D CD1 1 
ATOM   3793 C  CD2 . LEU B 2 348 ? 128.091 94.202  118.081 1.00 35.34  ? 348 LEU D CD2 1 
ATOM   3794 N  N   . GLN B 2 349 ? 133.253 95.239  119.440 1.00 44.13  ? 349 GLN D N   1 
ATOM   3795 C  CA  . GLN B 2 349 ? 134.485 94.589  119.873 1.00 44.13  ? 349 GLN D CA  1 
ATOM   3796 C  C   . GLN B 2 349 ? 134.711 94.776  121.368 1.00 44.13  ? 349 GLN D C   1 
ATOM   3797 O  O   . GLN B 2 349 ? 135.198 93.864  122.047 1.00 44.13  ? 349 GLN D O   1 
ATOM   3798 C  CB  . GLN B 2 349 ? 135.670 95.131  119.075 1.00 44.13  ? 349 GLN D CB  1 
ATOM   3799 C  CG  . GLN B 2 349 ? 136.944 94.314  119.215 1.00 44.13  ? 349 GLN D CG  1 
ATOM   3800 C  CD  . GLN B 2 349 ? 137.808 94.773  120.372 1.00 44.13  ? 349 GLN D CD  1 
ATOM   3801 O  OE1 . GLN B 2 349 ? 137.587 95.842  120.940 1.00 44.13  ? 349 GLN D OE1 1 
ATOM   3802 N  NE2 . GLN B 2 349 ? 138.798 93.964  120.728 1.00 44.13  ? 349 GLN D NE2 1 
ATOM   3803 N  N   . ARG B 2 350 ? 134.371 95.953  121.897 1.00 44.99  ? 350 ARG D N   1 
ATOM   3804 C  CA  . ARG B 2 350 ? 134.567 96.219  123.317 1.00 44.99  ? 350 ARG D CA  1 
ATOM   3805 C  C   . ARG B 2 350 ? 133.646 95.375  124.188 1.00 44.99  ? 350 ARG D C   1 
ATOM   3806 O  O   . ARG B 2 350 ? 134.076 94.875  125.234 1.00 44.99  ? 350 ARG D O   1 
ATOM   3807 C  CB  . ARG B 2 350 ? 134.352 97.705  123.601 1.00 44.99  ? 350 ARG D CB  1 
ATOM   3808 C  CG  . ARG B 2 350 ? 134.767 98.144  124.992 1.00 44.99  ? 350 ARG D CG  1 
ATOM   3809 C  CD  . ARG B 2 350 ? 135.240 99.587  124.986 1.00 44.99  ? 350 ARG D CD  1 
ATOM   3810 N  NE  . ARG B 2 350 ? 134.266 100.476 124.365 1.00 44.99  ? 350 ARG D NE  1 
ATOM   3811 C  CZ  . ARG B 2 350 ? 133.316 101.125 125.024 1.00 44.99  ? 350 ARG D CZ  1 
ATOM   3812 N  NH1 . ARG B 2 350 ? 133.184 101.012 126.335 1.00 44.99  ? 350 ARG D NH1 1 
ATOM   3813 N  NH2 . ARG B 2 350 ? 132.480 101.909 124.350 1.00 44.99  ? 350 ARG D NH2 1 
ATOM   3814 N  N   . HIS B 2 351 ? 132.388 95.204  123.786 1.00 43.52  ? 351 HIS D N   1 
ATOM   3815 C  CA  . HIS B 2 351 ? 131.429 94.451  124.584 1.00 43.52  ? 351 HIS D CA  1 
ATOM   3816 C  C   . HIS B 2 351 ? 131.240 93.015  124.112 1.00 43.52  ? 351 HIS D C   1 
ATOM   3817 O  O   . HIS B 2 351 ? 130.354 92.325  124.625 1.00 43.52  ? 351 HIS D O   1 
ATOM   3818 C  CB  . HIS B 2 351 ? 130.082 95.174  124.607 1.00 43.52  ? 351 HIS D CB  1 
ATOM   3819 C  CG  . HIS B 2 351 ? 130.076 96.396  125.469 1.00 43.52  ? 351 HIS D CG  1 
ATOM   3820 N  ND1 . HIS B 2 351 ? 130.373 97.651  124.985 1.00 43.52  ? 351 HIS D ND1 1 
ATOM   3821 C  CD2 . HIS B 2 351 ? 129.820 96.553  126.789 1.00 43.52  ? 351 HIS D CD2 1 
ATOM   3822 C  CE1 . HIS B 2 351 ? 130.295 98.529  125.968 1.00 43.52  ? 351 HIS D CE1 1 
ATOM   3823 N  NE2 . HIS B 2 351 ? 129.961 97.889  127.073 1.00 43.52  ? 351 HIS D NE2 1 
ATOM   3824 N  N   . ARG B 2 352 ? 132.049 92.552  123.157 1.00 47.71  ? 352 ARG D N   1 
ATOM   3825 C  CA  . ARG B 2 352 ? 132.026 91.162  122.696 1.00 47.71  ? 352 ARG D CA  1 
ATOM   3826 C  C   . ARG B 2 352 ? 130.640 90.739  122.215 1.00 47.71  ? 352 ARG D C   1 
ATOM   3827 O  O   . ARG B 2 352 ? 130.176 89.637  122.517 1.00 47.71  ? 352 ARG D O   1 
ATOM   3828 C  CB  . ARG B 2 352 ? 132.522 90.211  123.790 1.00 47.71  ? 352 ARG D CB  1 
ATOM   3829 C  CG  . ARG B 2 352 ? 133.275 88.998  123.269 1.00 47.71  ? 352 ARG D CG  1 
ATOM   3830 C  CD  . ARG B 2 352 ? 133.810 88.148  124.410 1.00 47.71  ? 352 ARG D CD  1 
ATOM   3831 N  NE  . ARG B 2 352 ? 134.879 88.819  125.140 1.00 47.71  ? 352 ARG D NE  1 
ATOM   3832 C  CZ  . ARG B 2 352 ? 134.738 89.370  126.338 1.00 47.71  ? 352 ARG D CZ  1 
ATOM   3833 N  NH1 . ARG B 2 352 ? 133.580 89.348  126.976 1.00 47.71  ? 352 ARG D NH1 1 
ATOM   3834 N  NH2 . ARG B 2 352 ? 135.786 89.958  126.909 1.00 47.71  ? 352 ARG D NH2 1 
ATOM   3835 N  N   . LEU B 2 353 ? 129.969 91.606  121.467 1.00 38.25  ? 353 LEU D N   1 
ATOM   3836 C  CA  . LEU B 2 353 ? 128.644 91.309  120.949 1.00 38.25  ? 353 LEU D CA  1 
ATOM   3837 C  C   . LEU B 2 353 ? 128.705 91.015  119.452 1.00 38.25  ? 353 LEU D C   1 
ATOM   3838 O  O   . LEU B 2 353 ? 129.694 91.304  118.775 1.00 38.25  ? 353 LEU D O   1 
ATOM   3839 C  CB  . LEU B 2 353 ? 127.690 92.472  121.220 1.00 38.25  ? 353 LEU D CB  1 
ATOM   3840 C  CG  . LEU B 2 353 ? 127.545 92.901  122.680 1.00 38.25  ? 353 LEU D CG  1 
ATOM   3841 C  CD1 . LEU B 2 353 ? 126.679 94.143  122.783 1.00 38.25  ? 353 LEU D CD1 1 
ATOM   3842 C  CD2 . LEU B 2 353 ? 126.971 91.771  123.515 1.00 38.25  ? 353 LEU D CD2 1 
ATOM   3843 N  N   . SER B 2 354 ? 127.622 90.432  118.939 1.00 35.16  ? 354 SER D N   1 
ATOM   3844 C  CA  . SER B 2 354 ? 127.534 90.104  117.521 1.00 35.16  ? 354 SER D CA  1 
ATOM   3845 C  C   . SER B 2 354 ? 126.884 91.224  116.715 1.00 35.16  ? 354 SER D C   1 
ATOM   3846 O  O   . SER B 2 354 ? 127.492 91.750  115.780 1.00 35.16  ? 354 SER D O   1 
ATOM   3847 C  CB  . SER B 2 354 ? 126.761 88.797  117.329 1.00 35.16  ? 354 SER D CB  1 
ATOM   3848 O  OG  . SER B 2 354 ? 127.561 87.681  117.674 1.00 35.16  ? 354 SER D OG  1 
ATOM   3849 N  N   . TYR B 2 355 ? 125.656 91.597  117.063 1.00 33.26  ? 355 TYR D N   1 
ATOM   3850 C  CA  . TYR B 2 355 ? 124.964 92.680  116.379 1.00 33.26  ? 355 TYR D CA  1 
ATOM   3851 C  C   . TYR B 2 355 ? 123.934 93.272  117.329 1.00 33.26  ? 355 TYR D C   1 
ATOM   3852 O  O   . TYR B 2 355 ? 123.570 92.667  118.339 1.00 33.26  ? 355 TYR D O   1 
ATOM   3853 C  CB  . TYR B 2 355 ? 124.314 92.200  115.076 1.00 33.26  ? 355 TYR D CB  1 
ATOM   3854 C  CG  . TYR B 2 355 ? 123.354 91.044  115.240 1.00 33.26  ? 355 TYR D CG  1 
ATOM   3855 C  CD1 . TYR B 2 355 ? 121.994 91.264  115.406 1.00 33.26  ? 355 TYR D CD1 1 
ATOM   3856 C  CD2 . TYR B 2 355 ? 123.806 89.733  115.217 1.00 33.26  ? 355 TYR D CD2 1 
ATOM   3857 C  CE1 . TYR B 2 355 ? 121.114 90.211  115.552 1.00 33.26  ? 355 TYR D CE1 1 
ATOM   3858 C  CE2 . TYR B 2 355 ? 122.933 88.674  115.362 1.00 33.26  ? 355 TYR D CE2 1 
ATOM   3859 C  CZ  . TYR B 2 355 ? 121.589 88.920  115.530 1.00 33.26  ? 355 TYR D CZ  1 
ATOM   3860 O  OH  . TYR B 2 355 ? 120.716 87.868  115.675 1.00 33.26  ? 355 TYR D OH  1 
ATOM   3861 N  N   . VAL B 2 356 ? 123.469 94.471  116.991 1.00 37.84  ? 356 VAL D N   1 
ATOM   3862 C  CA  . VAL B 2 356 ? 122.545 95.230  117.823 1.00 37.84  ? 356 VAL D CA  1 
ATOM   3863 C  C   . VAL B 2 356 ? 121.242 95.423  117.064 1.00 37.84  ? 356 VAL D C   1 
ATOM   3864 O  O   . VAL B 2 356 ? 121.246 95.873  115.913 1.00 37.84  ? 356 VAL D O   1 
ATOM   3865 C  CB  . VAL B 2 356 ? 123.145 96.592  118.229 1.00 37.84  ? 356 VAL D CB  1 
ATOM   3866 C  CG1 . VAL B 2 356 ? 122.127 97.415  118.998 1.00 37.84  ? 356 VAL D CG1 1 
ATOM   3867 C  CG2 . VAL B 2 356 ? 124.409 96.391  119.047 1.00 37.84  ? 356 VAL D CG2 1 
ATOM   3868 N  N   . ILE B 2 357 ? 120.129 95.085  117.708 1.00 51.63  ? 357 ILE D N   1 
ATOM   3869 C  CA  . ILE B 2 357 ? 118.800 95.270  117.136 1.00 51.63  ? 357 ILE D CA  1 
ATOM   3870 C  C   . ILE B 2 357 ? 118.264 96.621  117.585 1.00 51.63  ? 357 ILE D C   1 
ATOM   3871 O  O   . ILE B 2 357 ? 118.508 97.057  118.717 1.00 51.63  ? 357 ILE D O   1 
ATOM   3872 C  CB  . ILE B 2 357 ? 117.854 94.124  117.539 1.00 51.63  ? 357 ILE D CB  1 
ATOM   3873 C  CG1 . ILE B 2 357 ? 118.498 92.776  117.215 1.00 51.63  ? 357 ILE D CG1 1 
ATOM   3874 C  CG2 . ILE B 2 357 ? 116.521 94.246  116.823 1.00 51.63  ? 357 ILE D CG2 1 
ATOM   3875 C  CD1 . ILE B 2 357 ? 117.593 91.594  117.452 1.00 51.63  ? 357 ILE D CD1 1 
ATOM   3876 N  N   . ARG B 2 358 ? 117.535 97.289  116.696 1.00 51.63  ? 358 ARG D N   1 
ATOM   3877 C  CA  . ARG B 2 358 ? 117.124 98.669  116.893 1.00 51.63  ? 358 ARG D CA  1 
ATOM   3878 C  C   . ARG B 2 358 ? 115.704 98.846  116.375 1.00 51.63  ? 358 ARG D C   1 
ATOM   3879 O  O   . ARG B 2 358 ? 115.250 98.110  115.497 1.00 51.63  ? 358 ARG D O   1 
ATOM   3880 C  CB  . ARG B 2 358 ? 118.085 99.620  116.176 1.00 51.63  ? 358 ARG D CB  1 
ATOM   3881 C  CG  . ARG B 2 358 ? 118.087 101.040 116.673 1.00 51.63  ? 358 ARG D CG  1 
ATOM   3882 C  CD  . ARG B 2 358 ? 119.006 101.870 115.807 1.00 51.63  ? 358 ARG D CD  1 
ATOM   3883 N  NE  . ARG B 2 358 ? 118.367 102.222 114.547 1.00 51.63  ? 358 ARG D NE  1 
ATOM   3884 C  CZ  . ARG B 2 358 ? 117.724 103.359 114.327 1.00 51.63  ? 358 ARG D CZ  1 
ATOM   3885 N  NH1 . ARG B 2 358 ? 117.634 104.293 115.259 1.00 51.63  ? 358 ARG D NH1 1 
ATOM   3886 N  NH2 . ARG B 2 358 ? 117.168 103.570 113.138 1.00 51.63  ? 358 ARG D NH2 1 
ATOM   3887 N  N   . SER B 2 359 ? 114.994 99.830  116.932 1.00 51.63  ? 359 SER D N   1 
ATOM   3888 C  CA  . SER B 2 359 ? 113.606 100.045 116.547 1.00 51.63  ? 359 SER D CA  1 
ATOM   3889 C  C   . SER B 2 359 ? 113.184 101.504 116.444 1.00 51.63  ? 359 SER D C   1 
ATOM   3890 O  O   . SER B 2 359 ? 111.981 101.766 116.367 1.00 51.63  ? 359 SER D O   1 
ATOM   3891 C  CB  . SER B 2 359 ? 112.671 99.331  117.532 1.00 51.63  ? 359 SER D CB  1 
ATOM   3892 O  OG  . SER B 2 359 ? 111.316 99.512  117.162 1.00 51.63  ? 359 SER D OG  1 
ATOM   3893 N  N   . HIS B 2 360 ? 114.113 102.459 116.438 1.00 37.76  ? 360 HIS D N   1 
ATOM   3894 C  CA  . HIS B 2 360 ? 113.715 103.859 116.558 1.00 37.76  ? 360 HIS D CA  1 
ATOM   3895 C  C   . HIS B 2 360 ? 113.067 104.386 115.282 1.00 37.76  ? 360 HIS D C   1 
ATOM   3896 O  O   . HIS B 2 360 ? 112.031 105.058 115.341 1.00 37.76  ? 360 HIS D O   1 
ATOM   3897 C  CB  . HIS B 2 360 ? 114.921 104.714 116.939 1.00 37.76  ? 360 HIS D CB  1 
ATOM   3898 C  CG  . HIS B 2 360 ? 114.562 105.979 117.651 1.00 37.76  ? 360 HIS D CG  1 
ATOM   3899 N  ND1 . HIS B 2 360 ? 115.282 107.145 117.504 1.00 37.76  ? 360 HIS D ND1 1 
ATOM   3900 C  CD2 . HIS B 2 360 ? 113.558 106.263 118.513 1.00 37.76  ? 360 HIS D CD2 1 
ATOM   3901 C  CE1 . HIS B 2 360 ? 114.738 108.092 118.247 1.00 37.76  ? 360 HIS D CE1 1 
ATOM   3902 N  NE2 . HIS B 2 360 ? 113.690 107.583 118.869 1.00 37.76  ? 360 HIS D NE2 1 
ATOM   3903 N  N   . GLU B 2 361 ? 113.651 104.095 114.123 1.00 37.51  ? 361 GLU D N   1 
ATOM   3904 C  CA  . GLU B 2 361 ? 113.254 104.729 112.872 1.00 37.51  ? 361 GLU D CA  1 
ATOM   3905 C  C   . GLU B 2 361 ? 112.308 103.830 112.088 1.00 37.51  ? 361 GLU D C   1 
ATOM   3906 O  O   . GLU B 2 361 ? 112.566 102.632 111.934 1.00 37.51  ? 361 GLU D O   1 
ATOM   3907 C  CB  . GLU B 2 361 ? 114.477 105.058 112.017 1.00 37.51  ? 361 GLU D CB  1 
ATOM   3908 C  CG  . GLU B 2 361 ? 115.302 106.222 112.525 1.00 37.51  ? 361 GLU D CG  1 
ATOM   3909 C  CD  . GLU B 2 361 ? 116.465 106.547 111.611 1.00 37.51  ? 361 GLU D CD  1 
ATOM   3910 O  OE1 . GLU B 2 361 ? 117.049 105.606 111.034 1.00 37.51  ? 361 GLU D OE1 1 
ATOM   3911 O  OE2 . GLU B 2 361 ? 116.798 107.742 111.470 1.00 37.51  ? 361 GLU D OE2 1 
ATOM   3912 N  N   . CYS B 2 362 ? 111.221 104.414 111.592 1.00 46.82  ? 362 CYS D N   1 
ATOM   3913 C  CA  . CYS B 2 362 ? 110.313 103.693 110.713 1.00 46.82  ? 362 CYS D CA  1 
ATOM   3914 C  C   . CYS B 2 362 ? 110.939 103.508 109.335 1.00 46.82  ? 362 CYS D C   1 
ATOM   3915 O  O   . CYS B 2 362 ? 111.731 104.333 108.871 1.00 46.82  ? 362 CYS D O   1 
ATOM   3916 C  CB  . CYS B 2 362 ? 108.985 104.437 110.588 1.00 46.82  ? 362 CYS D CB  1 
ATOM   3917 S  SG  . CYS B 2 362 ? 109.125 106.085 109.865 1.00 46.82  ? 362 CYS D SG  1 
ATOM   3918 N  N   . LYS B 2 363 ? 110.576 102.412 108.679 1.00 37.19  ? 363 LYS D N   1 
ATOM   3919 C  CA  . LYS B 2 363 ? 111.112 102.070 107.372 1.00 37.19  ? 363 LYS D CA  1 
ATOM   3920 C  C   . LYS B 2 363 ? 109.966 101.725 106.435 1.00 37.19  ? 363 LYS D C   1 
ATOM   3921 O  O   . LYS B 2 363 ? 108.921 101.239 106.884 1.00 37.19  ? 363 LYS D O   1 
ATOM   3922 C  CB  . LYS B 2 363 ? 112.089 100.888 107.461 1.00 37.19  ? 363 LYS D CB  1 
ATOM   3923 C  CG  . LYS B 2 363 ? 113.308 101.164 108.324 1.00 37.19  ? 363 LYS D CG  1 
ATOM   3924 C  CD  . LYS B 2 363 ? 114.186 102.236 107.704 1.00 37.19  ? 363 LYS D CD  1 
ATOM   3925 C  CE  . LYS B 2 363 ? 115.412 102.510 108.559 1.00 37.19  ? 363 LYS D CE  1 
ATOM   3926 N  NZ  . LYS B 2 363 ? 116.248 103.603 107.992 1.00 37.19  ? 363 LYS D NZ  1 
ATOM   3927 N  N   . PRO B 2 364 ? 110.124 101.980 105.131 1.00 35.04  ? 364 PRO D N   1 
ATOM   3928 C  CA  . PRO B 2 364 ? 109.030 101.670 104.193 1.00 35.04  ? 364 PRO D CA  1 
ATOM   3929 C  C   . PRO B 2 364 ? 108.633 100.206 104.187 1.00 35.04  ? 364 PRO D C   1 
ATOM   3930 O  O   . PRO B 2 364 ? 107.441 99.892  104.079 1.00 35.04  ? 364 PRO D O   1 
ATOM   3931 C  CB  . PRO B 2 364 ? 109.600 102.110 102.837 1.00 35.04  ? 364 PRO D CB  1 
ATOM   3932 C  CG  . PRO B 2 364 ? 110.676 103.087 103.174 1.00 35.04  ? 364 PRO D CG  1 
ATOM   3933 C  CD  . PRO B 2 364 ? 111.275 102.594 104.450 1.00 35.04  ? 364 PRO D CD  1 
ATOM   3934 N  N   . ASN B 2 365 ? 109.598 99.297  104.297 1.00 38.24  ? 365 ASN D N   1 
ATOM   3935 C  CA  . ASN B 2 365 ? 109.317 97.870  104.367 1.00 38.24  ? 365 ASN D CA  1 
ATOM   3936 C  C   . ASN B 2 365 ? 109.250 97.351  105.795 1.00 38.24  ? 365 ASN D C   1 
ATOM   3937 O  O   . ASN B 2 365 ? 109.000 96.159  105.994 1.00 38.24  ? 365 ASN D O   1 
ATOM   3938 C  CB  . ASN B 2 365 ? 110.373 97.083  103.587 1.00 38.24  ? 365 ASN D CB  1 
ATOM   3939 C  CG  . ASN B 2 365 ? 110.240 97.256  102.091 1.00 38.24  ? 365 ASN D CG  1 
ATOM   3940 O  OD1 . ASN B 2 365 ? 109.148 97.133  101.535 1.00 38.24  ? 365 ASN D OD1 1 
ATOM   3941 N  ND2 . ASN B 2 365 ? 111.353 97.542  101.427 1.00 38.24  ? 365 ASN D ND2 1 
ATOM   3942 N  N   . GLY B 2 366 ? 109.469 98.211  106.788 1.00 40.13  ? 366 GLY D N   1 
ATOM   3943 C  CA  . GLY B 2 366 ? 109.434 97.808  108.175 1.00 40.13  ? 366 GLY D CA  1 
ATOM   3944 C  C   . GLY B 2 366 ? 110.738 97.283  108.731 1.00 40.13  ? 366 GLY D C   1 
ATOM   3945 O  O   . GLY B 2 366 ? 110.817 97.037  109.940 1.00 40.13  ? 366 GLY D O   1 
ATOM   3946 N  N   . HIS B 2 367 ? 111.763 97.105  107.901 1.00 41.84  ? 367 HIS D N   1 
ATOM   3947 C  CA  . HIS B 2 367 ? 113.043 96.601  108.374 1.00 41.84  ? 367 HIS D CA  1 
ATOM   3948 C  C   . HIS B 2 367 ? 114.126 96.941  107.363 1.00 41.84  ? 367 HIS D C   1 
ATOM   3949 O  O   . HIS B 2 367 ? 113.878 97.006  106.157 1.00 41.84  ? 367 HIS D O   1 
ATOM   3950 C  CB  . HIS B 2 367 ? 112.996 95.089  108.616 1.00 41.84  ? 367 HIS D CB  1 
ATOM   3951 C  CG  . HIS B 2 367 ? 112.621 94.297  107.404 1.00 41.84  ? 367 HIS D CG  1 
ATOM   3952 N  ND1 . HIS B 2 367 ? 113.550 93.639  106.628 1.00 41.84  ? 367 HIS D ND1 1 
ATOM   3953 C  CD2 . HIS B 2 367 ? 111.416 94.052  106.836 1.00 41.84  ? 367 HIS D CD2 1 
ATOM   3954 C  CE1 . HIS B 2 367 ? 112.936 93.026  105.633 1.00 41.84  ? 367 HIS D CE1 1 
ATOM   3955 N  NE2 . HIS B 2 367 ? 111.640 93.260  105.736 1.00 41.84  ? 367 HIS D NE2 1 
ATOM   3956 N  N   . GLU B 2 368 ? 115.340 97.145  107.872 1.00 40.78  ? 368 GLU D N   1 
ATOM   3957 C  CA  . GLU B 2 368 ? 116.483 97.487  107.038 1.00 40.78  ? 368 GLU D CA  1 
ATOM   3958 C  C   . GLU B 2 368 ? 117.757 97.001  107.711 1.00 40.78  ? 368 GLU D C   1 
ATOM   3959 O  O   . GLU B 2 368 ? 117.760 96.626  108.885 1.00 40.78  ? 368 GLU D O   1 
ATOM   3960 C  CB  . GLU B 2 368 ? 116.570 98.996  106.779 1.00 40.78  ? 368 GLU D CB  1 
ATOM   3961 C  CG  . GLU B 2 368 ? 115.701 99.495  105.635 1.00 40.78  ? 368 GLU D CG  1 
ATOM   3962 C  CD  . GLU B 2 368 ? 116.349 100.625 104.859 1.00 40.78  ? 368 GLU D CD  1 
ATOM   3963 O  OE1 . GLU B 2 368 ? 116.632 101.679 105.466 1.00 40.78  ? 368 GLU D OE1 1 
ATOM   3964 O  OE2 . GLU B 2 368 ? 116.574 100.459 103.642 1.00 40.78  ? 368 GLU D OE2 1 
ATOM   3965 N  N   . PHE B 2 369 ? 118.842 97.006  106.944 1.00 40.53  ? 369 PHE D N   1 
ATOM   3966 C  CA  . PHE B 2 369 ? 120.167 96.672  107.441 1.00 40.53  ? 369 PHE D CA  1 
ATOM   3967 C  C   . PHE B 2 369 ? 121.098 97.866  107.275 1.00 40.53  ? 369 PHE D C   1 
ATOM   3968 O  O   . PHE B 2 369 ? 120.979 98.639  106.322 1.00 40.53  ? 369 PHE D O   1 
ATOM   3969 C  CB  . PHE B 2 369 ? 120.746 95.465  106.701 1.00 40.53  ? 369 PHE D CB  1 
ATOM   3970 C  CG  . PHE B 2 369 ? 120.181 94.148  107.146 1.00 40.53  ? 369 PHE D CG  1 
ATOM   3971 C  CD1 . PHE B 2 369 ? 118.914 93.756  106.757 1.00 40.53  ? 369 PHE D CD1 1 
ATOM   3972 C  CD2 . PHE B 2 369 ? 120.927 93.296  107.940 1.00 40.53  ? 369 PHE D CD2 1 
ATOM   3973 C  CE1 . PHE B 2 369 ? 118.397 92.542  107.160 1.00 40.53  ? 369 PHE D CE1 1 
ATOM   3974 C  CE2 . PHE B 2 369 ? 120.416 92.081  108.346 1.00 40.53  ? 369 PHE D CE2 1 
ATOM   3975 C  CZ  . PHE B 2 369 ? 119.149 91.704  107.956 1.00 40.53  ? 369 PHE D CZ  1 
ATOM   3976 N  N   . MET B 2 370 ? 122.032 98.009  108.213 1.00 38.79  ? 370 MET D N   1 
ATOM   3977 C  CA  . MET B 2 370 ? 122.986 99.108  108.188 1.00 38.79  ? 370 MET D CA  1 
ATOM   3978 C  C   . MET B 2 370 ? 124.317 98.639  108.758 1.00 38.79  ? 370 MET D C   1 
ATOM   3979 O  O   . MET B 2 370 ? 124.383 97.693  109.547 1.00 38.79  ? 370 MET D O   1 
ATOM   3980 C  CB  . MET B 2 370 ? 122.468 100.321 108.972 1.00 38.79  ? 370 MET D CB  1 
ATOM   3981 C  CG  . MET B 2 370 ? 121.452 101.162 108.221 1.00 38.79  ? 370 MET D CG  1 
ATOM   3982 S  SD  . MET B 2 370 ? 121.457 102.890 108.730 1.00 38.79  ? 370 MET D SD  1 
ATOM   3983 C  CE  . MET B 2 370 ? 120.687 103.663 107.310 1.00 38.79  ? 370 MET D CE  1 
ATOM   3984 N  N   . HIS B 2 371 ? 125.382 99.322  108.342 1.00 35.30  ? 371 HIS D N   1 
ATOM   3985 C  CA  . HIS B 2 371 ? 126.736 99.108  108.853 1.00 35.30  ? 371 HIS D CA  1 
ATOM   3986 C  C   . HIS B 2 371 ? 127.163 97.647  108.711 1.00 35.30  ? 371 HIS D C   1 
ATOM   3987 O  O   . HIS B 2 371 ? 127.584 96.994  109.668 1.00 35.30  ? 371 HIS D O   1 
ATOM   3988 C  CB  . HIS B 2 371 ? 126.853 99.573  110.307 1.00 35.30  ? 371 HIS D CB  1 
ATOM   3989 C  CG  . HIS B 2 371 ? 126.439 100.995 110.528 1.00 35.30  ? 371 HIS D CG  1 
ATOM   3990 N  ND1 . HIS B 2 371 ? 126.559 101.622 111.749 1.00 35.30  ? 371 HIS D ND1 1 
ATOM   3991 C  CD2 . HIS B 2 371 ? 125.909 101.914 109.685 1.00 35.30  ? 371 HIS D CD2 1 
ATOM   3992 C  CE1 . HIS B 2 371 ? 126.120 102.863 111.650 1.00 35.30  ? 371 HIS D CE1 1 
ATOM   3993 N  NE2 . HIS B 2 371 ? 125.719 103.066 110.408 1.00 35.30  ? 371 HIS D NE2 1 
ATOM   3994 N  N   . ASP B 2 372 ? 127.048 97.144  107.481 1.00 47.74  ? 372 ASP D N   1 
ATOM   3995 C  CA  . ASP B 2 372 ? 127.467 95.785  107.131 1.00 47.74  ? 372 ASP D CA  1 
ATOM   3996 C  C   . ASP B 2 372 ? 126.744 94.764  108.012 1.00 47.74  ? 372 ASP D C   1 
ATOM   3997 O  O   . ASP B 2 372 ? 127.360 94.051  108.808 1.00 47.74  ? 372 ASP D O   1 
ATOM   3998 C  CB  . ASP B 2 372 ? 128.992 95.643  107.234 1.00 47.74  ? 372 ASP D CB  1 
ATOM   3999 C  CG  . ASP B 2 372 ? 129.512 94.271  106.796 1.00 47.74  ? 372 ASP D CG  1 
ATOM   4000 O  OD1 . ASP B 2 372 ? 128.738 93.296  106.697 1.00 47.74  ? 372 ASP D OD1 1 
ATOM   4001 O  OD2 . ASP B 2 372 ? 130.731 94.172  106.546 1.00 47.74  ? 372 ASP D OD2 1 
ATOM   4002 N  N   . ASN B 2 373 ? 125.417 94.725  107.897 1.00 46.49  ? 373 ASN D N   1 
ATOM   4003 C  CA  . ASN B 2 373 ? 124.540 93.771  108.572 1.00 46.49  ? 373 ASN D CA  1 
ATOM   4004 C  C   . ASN B 2 373 ? 124.774 93.680  110.075 1.00 46.49  ? 373 ASN D C   1 
ATOM   4005 O  O   . ASN B 2 373 ? 124.514 92.626  110.668 1.00 46.49  ? 373 ASN D O   1 
ATOM   4006 C  CB  . ASN B 2 373 ? 124.660 92.370  107.964 1.00 46.49  ? 373 ASN D CB  1 
ATOM   4007 C  CG  . ASN B 2 373 ? 124.345 92.349  106.483 1.00 46.49  ? 373 ASN D CG  1 
ATOM   4008 O  OD1 . ASN B 2 373 ? 123.450 93.055  106.018 1.00 46.49  ? 373 ASN D OD1 1 
ATOM   4009 N  ND2 . ASN B 2 373 ? 125.079 91.536  105.733 1.00 46.49  ? 373 ASN D ND2 1 
ATOM   4010 N  N   . LYS B 2 374 ? 125.260 94.746  110.713 1.00 29.17  ? 374 LYS D N   1 
ATOM   4011 C  CA  . LYS B 2 374 ? 125.493 94.703  112.151 1.00 29.17  ? 374 LYS D CA  1 
ATOM   4012 C  C   . LYS B 2 374 ? 124.481 95.521  112.939 1.00 29.17  ? 374 LYS D C   1 
ATOM   4013 O  O   . LYS B 2 374 ? 124.449 95.419  114.169 1.00 29.17  ? 374 LYS D O   1 
ATOM   4014 C  CB  . LYS B 2 374 ? 126.909 95.181  112.473 1.00 29.17  ? 374 LYS D CB  1 
ATOM   4015 C  CG  . LYS B 2 374 ? 127.949 94.078  112.418 1.00 29.17  ? 374 LYS D CG  1 
ATOM   4016 C  CD  . LYS B 2 374 ? 129.355 94.628  112.552 1.00 29.17  ? 374 LYS D CD  1 
ATOM   4017 C  CE  . LYS B 2 374 ? 130.355 93.512  112.801 1.00 29.17  ? 374 LYS D CE  1 
ATOM   4018 N  NZ  . LYS B 2 374 ? 131.760 93.983  112.664 1.00 29.17  ? 374 LYS D NZ  1 
ATOM   4019 N  N   . ILE B 2 375 ? 123.663 96.326  112.268 1.00 37.33  ? 375 ILE D N   1 
ATOM   4020 C  CA  . ILE B 2 375 ? 122.588 97.076  112.906 1.00 37.33  ? 375 ILE D CA  1 
ATOM   4021 C  C   . ILE B 2 375 ? 121.295 96.754  112.174 1.00 37.33  ? 375 ILE D C   1 
ATOM   4022 O  O   . ILE B 2 375 ? 121.156 97.067  110.987 1.00 37.33  ? 375 ILE D O   1 
ATOM   4023 C  CB  . ILE B 2 375 ? 122.861 98.590  112.893 1.00 37.33  ? 375 ILE D CB  1 
ATOM   4024 C  CG1 . ILE B 2 375 ? 124.122 98.912  113.693 1.00 37.33  ? 375 ILE D CG1 1 
ATOM   4025 C  CG2 . ILE B 2 375 ? 121.673 99.347  113.455 1.00 37.33  ? 375 ILE D CG2 1 
ATOM   4026 C  CD1 . ILE B 2 375 ? 123.995 98.621  115.165 1.00 37.33  ? 375 ILE D CD1 1 
ATOM   4027 N  N   . ILE B 2 376 ? 120.353 96.138  112.881 1.00 51.63  ? 376 ILE D N   1 
ATOM   4028 C  CA  . ILE B 2 376 ? 119.080 95.718  112.310 1.00 51.63  ? 376 ILE D CA  1 
ATOM   4029 C  C   . ILE B 2 376 ? 117.987 96.619  112.860 1.00 51.63  ? 376 ILE D C   1 
ATOM   4030 O  O   . ILE B 2 376 ? 117.756 96.656  114.074 1.00 51.63  ? 376 ILE D O   1 
ATOM   4031 C  CB  . ILE B 2 376 ? 118.779 94.243  112.624 1.00 51.63  ? 376 ILE D CB  1 
ATOM   4032 C  CG1 . ILE B 2 376 ? 119.905 93.346  112.114 1.00 51.63  ? 376 ILE D CG1 1 
ATOM   4033 C  CG2 . ILE B 2 376 ? 117.459 93.832  112.005 1.00 51.63  ? 376 ILE D CG2 1 
ATOM   4034 C  CD1 . ILE B 2 376 ? 119.755 91.902  112.521 1.00 51.63  ? 376 ILE D CD1 1 
ATOM   4035 N  N   . THR B 2 377 ? 117.314 97.339  111.971 1.00 51.63  ? 377 THR D N   1 
ATOM   4036 C  CA  . THR B 2 377 ? 116.213 98.215  112.341 1.00 51.63  ? 377 THR D CA  1 
ATOM   4037 C  C   . THR B 2 377 ? 114.900 97.481  112.110 1.00 51.63  ? 377 THR D C   1 
ATOM   4038 O  O   . THR B 2 377 ? 114.712 96.857  111.063 1.00 51.63  ? 377 THR D O   1 
ATOM   4039 C  CB  . THR B 2 377 ? 116.246 99.510  111.528 1.00 51.63  ? 377 THR D CB  1 
ATOM   4040 O  OG1 . THR B 2 377 ? 117.389 100.285 111.910 1.00 51.63  ? 377 THR D OG1 1 
ATOM   4041 C  CG2 . THR B 2 377 ? 114.987 100.326 111.767 1.00 51.63  ? 377 THR D CG2 1 
ATOM   4042 N  N   . ILE B 2 378 ? 114.004 97.545  113.091 1.00 51.63  ? 378 ILE D N   1 
ATOM   4043 C  CA  . ILE B 2 378 ? 112.696 96.909  113.005 1.00 51.63  ? 378 ILE D CA  1 
ATOM   4044 C  C   . ILE B 2 378 ? 111.635 97.942  113.354 1.00 51.63  ? 378 ILE D C   1 
ATOM   4045 O  O   . ILE B 2 378 ? 111.928 98.937  114.025 1.00 51.63  ? 378 ILE D O   1 
ATOM   4046 C  CB  . ILE B 2 378 ? 112.595 95.679  113.927 1.00 51.63  ? 378 ILE D CB  1 
ATOM   4047 C  CG1 . ILE B 2 378 ? 111.606 94.668  113.353 1.00 51.63  ? 378 ILE D CG1 1 
ATOM   4048 C  CG2 . ILE B 2 378 ? 112.196 96.083  115.331 1.00 51.63  ? 378 ILE D CG2 1 
ATOM   4049 C  CD1 . ILE B 2 378 ? 112.083 94.013  112.086 1.00 51.63  ? 378 ILE D CD1 1 
ATOM   4050 N  N   . PHE B 2 379 ? 110.412 97.718  112.882 1.00 51.63  ? 379 PHE D N   1 
ATOM   4051 C  CA  . PHE B 2 379 ? 109.311 98.644  113.103 1.00 51.63  ? 379 PHE D CA  1 
ATOM   4052 C  C   . PHE B 2 379 ? 108.004 97.903  112.878 1.00 51.63  ? 379 PHE D C   1 
ATOM   4053 O  O   . PHE B 2 379 ? 107.724 97.465  111.759 1.00 51.63  ? 379 PHE D O   1 
ATOM   4054 C  CB  . PHE B 2 379 ? 109.417 99.851  112.167 1.00 51.63  ? 379 PHE D CB  1 
ATOM   4055 C  CG  . PHE B 2 379 ? 108.593 101.025 112.597 1.00 51.63  ? 379 PHE D CG  1 
ATOM   4056 C  CD1 . PHE B 2 379 ? 109.056 101.890 113.570 1.00 51.63  ? 379 PHE D CD1 1 
ATOM   4057 C  CD2 . PHE B 2 379 ? 107.363 101.273 112.019 1.00 51.63  ? 379 PHE D CD2 1 
ATOM   4058 C  CE1 . PHE B 2 379 ? 108.304 102.975 113.966 1.00 51.63  ? 379 PHE D CE1 1 
ATOM   4059 C  CE2 . PHE B 2 379 ? 106.607 102.359 112.410 1.00 51.63  ? 379 PHE D CE2 1 
ATOM   4060 C  CZ  . PHE B 2 379 ? 107.078 103.210 113.385 1.00 51.63  ? 379 PHE D CZ  1 
ATOM   4061 N  N   . SER B 2 380 ? 107.205 97.770  113.936 1.00 51.63  ? 380 SER D N   1 
ATOM   4062 C  CA  . SER B 2 380 ? 106.016 96.932  113.906 1.00 51.63  ? 380 SER D CA  1 
ATOM   4063 C  C   . SER B 2 380 ? 104.712 97.710  113.818 1.00 51.63  ? 380 SER D C   1 
ATOM   4064 O  O   . SER B 2 380 ? 103.659 97.152  114.146 1.00 51.63  ? 380 SER D O   1 
ATOM   4065 C  CB  . SER B 2 380 ? 105.974 96.027  115.144 1.00 51.63  ? 380 SER D CB  1 
ATOM   4066 O  OG  . SER B 2 380 ? 107.160 95.262  115.255 1.00 51.63  ? 380 SER D OG  1 
ATOM   4067 N  N   . ALA B 2 381 ? 104.741 98.969  113.396 1.00 35.89  ? 381 ALA D N   1 
ATOM   4068 C  CA  . ALA B 2 381 ? 103.526 99.763  113.264 1.00 35.89  ? 381 ALA D CA  1 
ATOM   4069 C  C   . ALA B 2 381 ? 103.198 99.944  111.787 1.00 35.89  ? 381 ALA D C   1 
ATOM   4070 O  O   . ALA B 2 381 ? 103.935 100.618 111.060 1.00 35.89  ? 381 ALA D O   1 
ATOM   4071 C  CB  . ALA B 2 381 ? 103.684 101.117 113.950 1.00 35.89  ? 381 ALA D CB  1 
ATOM   4072 N  N   . SER B 2 382 ? 102.096 99.345  111.348 1.00 30.65  ? 382 SER D N   1 
ATOM   4073 C  CA  . SER B 2 382 ? 101.648 99.491  109.973 1.00 30.65  ? 382 SER D CA  1 
ATOM   4074 C  C   . SER B 2 382 ? 100.769 100.729 109.830 1.00 30.65  ? 382 SER D C   1 
ATOM   4075 O  O   . SER B 2 382 ? 100.053 101.124 110.754 1.00 30.65  ? 382 SER D O   1 
ATOM   4076 C  CB  . SER B 2 382 ? 100.884 98.248  109.521 1.00 30.65  ? 382 SER D CB  1 
ATOM   4077 O  OG  . SER B 2 382 ? 99.673  98.111  110.243 1.00 30.65  ? 382 SER D OG  1 
ATOM   4078 N  N   . ASN B 2 383 ? 100.826 101.338 108.644 1.00 27.30  ? 383 ASN D N   1 
ATOM   4079 C  CA  . ASN B 2 383 ? 100.115 102.586 108.366 1.00 27.30  ? 383 ASN D CA  1 
ATOM   4080 C  C   . ASN B 2 383 ? 100.481 103.657 109.390 1.00 27.30  ? 383 ASN D C   1 
ATOM   4081 O  O   . ASN B 2 383 ? 99.617  104.270 110.019 1.00 27.30  ? 383 ASN D O   1 
ATOM   4082 C  CB  . ASN B 2 383 ? 98.603  102.363 108.323 1.00 27.30  ? 383 ASN D CB  1 
ATOM   4083 C  CG  . ASN B 2 383 ? 98.191  101.386 107.245 1.00 27.30  ? 383 ASN D CG  1 
ATOM   4084 O  OD1 . ASN B 2 383 ? 98.836  101.286 106.202 1.00 27.30  ? 383 ASN D OD1 1 
ATOM   4085 N  ND2 . ASN B 2 383 ? 97.109  100.657 107.490 1.00 27.30  ? 383 ASN D ND2 1 
ATOM   4086 N  N   . TYR B 2 384 ? 101.786 103.876 109.561 1.00 28.60  ? 384 TYR D N   1 
ATOM   4087 C  CA  . TYR B 2 384 ? 102.261 104.784 110.599 1.00 28.60  ? 384 TYR D CA  1 
ATOM   4088 C  C   . TYR B 2 384 ? 101.869 106.227 110.303 1.00 28.60  ? 384 TYR D C   1 
ATOM   4089 O  O   . TYR B 2 384 ? 101.342 106.928 111.174 1.00 28.60  ? 384 TYR D O   1 
ATOM   4090 C  CB  . TYR B 2 384 ? 103.776 104.653 110.746 1.00 28.60  ? 384 TYR D CB  1 
ATOM   4091 C  CG  . TYR B 2 384 ? 104.353 105.456 111.886 1.00 28.60  ? 384 TYR D CG  1 
ATOM   4092 C  CD1 . TYR B 2 384 ? 103.807 105.382 113.158 1.00 28.60  ? 384 TYR D CD1 1 
ATOM   4093 C  CD2 . TYR B 2 384 ? 105.450 106.280 111.692 1.00 28.60  ? 384 TYR D CD2 1 
ATOM   4094 C  CE1 . TYR B 2 384 ? 104.333 106.113 114.201 1.00 28.60  ? 384 TYR D CE1 1 
ATOM   4095 C  CE2 . TYR B 2 384 ? 105.983 107.014 112.730 1.00 28.60  ? 384 TYR D CE2 1 
ATOM   4096 C  CZ  . TYR B 2 384 ? 105.421 106.927 113.982 1.00 28.60  ? 384 TYR D CZ  1 
ATOM   4097 O  OH  . TYR B 2 384 ? 105.950 107.657 115.019 1.00 28.60  ? 384 TYR D OH  1 
ATOM   4098 N  N   . TYR B 2 385 ? 102.114 106.689 109.077 1.00 27.01  ? 385 TYR D N   1 
ATOM   4099 C  CA  . TYR B 2 385 ? 101.832 108.073 108.714 1.00 27.01  ? 385 TYR D CA  1 
ATOM   4100 C  C   . TYR B 2 385 ? 100.404 108.249 108.210 1.00 27.01  ? 385 TYR D C   1 
ATOM   4101 O  O   . TYR B 2 385 ? 99.642  109.052 108.756 1.00 27.01  ? 385 TYR D O   1 
ATOM   4102 C  CB  . TYR B 2 385 ? 102.831 108.550 107.657 1.00 27.01  ? 385 TYR D CB  1 
ATOM   4103 C  CG  . TYR B 2 385 ? 104.260 108.601 108.148 1.00 27.01  ? 385 TYR D CG  1 
ATOM   4104 C  CD1 . TYR B 2 385 ? 104.660 109.546 109.081 1.00 27.01  ? 385 TYR D CD1 1 
ATOM   4105 C  CD2 . TYR B 2 385 ? 105.207 107.703 107.679 1.00 27.01  ? 385 TYR D CD2 1 
ATOM   4106 C  CE1 . TYR B 2 385 ? 105.963 109.595 109.532 1.00 27.01  ? 385 TYR D CE1 1 
ATOM   4107 C  CE2 . TYR B 2 385 ? 106.511 107.745 108.125 1.00 27.01  ? 385 TYR D CE2 1 
ATOM   4108 C  CZ  . TYR B 2 385 ? 106.884 108.692 109.051 1.00 27.01  ? 385 TYR D CZ  1 
ATOM   4109 O  OH  . TYR B 2 385 ? 108.183 108.738 109.498 1.00 27.01  ? 385 TYR D OH  1 
ATOM   4110 N  N   . ALA B 2 386 ? 100.032 107.511 107.169 1.00 30.89  ? 386 ALA D N   1 
ATOM   4111 C  CA  . ALA B 2 386 ? 98.672  107.522 106.651 1.00 30.89  ? 386 ALA D CA  1 
ATOM   4112 C  C   . ALA B 2 386 ? 98.362  106.126 106.135 1.00 30.89  ? 386 ALA D C   1 
ATOM   4113 O  O   . ALA B 2 386 ? 99.187  105.214 106.227 1.00 30.89  ? 386 ALA D O   1 
ATOM   4114 C  CB  . ALA B 2 386 ? 98.494  108.575 105.554 1.00 30.89  ? 386 ALA D CB  1 
ATOM   4115 N  N   . ILE B 2 387 ? 97.158  105.965 105.588 1.00 33.55  ? 387 ILE D N   1 
ATOM   4116 C  CA  . ILE B 2 387 ? 96.740  104.655 105.101 1.00 33.55  ? 387 ILE D CA  1 
ATOM   4117 C  C   . ILE B 2 387 ? 97.581  104.280 103.889 1.00 33.55  ? 387 ILE D C   1 
ATOM   4118 O  O   . ILE B 2 387 ? 97.470  104.895 102.822 1.00 33.55  ? 387 ILE D O   1 
ATOM   4119 C  CB  . ILE B 2 387 ? 95.245  104.654 104.774 1.00 33.55  ? 387 ILE D CB  1 
ATOM   4120 C  CG1 . ILE B 2 387 ? 94.430  104.963 106.030 1.00 33.55  ? 387 ILE D CG1 1 
ATOM   4121 C  CG2 . ILE B 2 387 ? 94.835  103.314 104.189 1.00 33.55  ? 387 ILE D CG2 1 
ATOM   4122 C  CD1 . ILE B 2 387 ? 92.947  105.108 105.775 1.00 33.55  ? 387 ILE D CD1 1 
ATOM   4123 N  N   . GLY B 2 388 ? 98.423  103.261 104.047 1.00 36.11  ? 388 GLY D N   1 
ATOM   4124 C  CA  . GLY B 2 388 ? 99.289  102.800 102.983 1.00 36.11  ? 388 GLY D CA  1 
ATOM   4125 C  C   . GLY B 2 388 ? 100.700 103.348 103.005 1.00 36.11  ? 388 GLY D C   1 
ATOM   4126 O  O   . GLY B 2 388 ? 101.421 103.182 102.015 1.00 36.11  ? 388 GLY D O   1 
ATOM   4127 N  N   . SER B 2 389 ? 101.116 103.997 104.095 1.00 30.20  ? 389 SER D N   1 
ATOM   4128 C  CA  . SER B 2 389 ? 102.448 104.593 104.135 1.00 30.20  ? 389 SER D CA  1 
ATOM   4129 C  C   . SER B 2 389 ? 103.542 103.533 104.162 1.00 30.20  ? 389 SER D C   1 
ATOM   4130 O  O   . SER B 2 389 ? 104.507 103.613 103.393 1.00 30.20  ? 389 SER D O   1 
ATOM   4131 C  CB  . SER B 2 389 ? 102.576 105.515 105.345 1.00 30.20  ? 389 SER D CB  1 
ATOM   4132 O  OG  . SER B 2 389 ? 101.368 106.210 105.582 1.00 30.20  ? 389 SER D OG  1 
ATOM   4133 N  N   . ASN B 2 390 ? 103.417 102.535 105.035 1.00 28.32  ? 390 ASN D N   1 
ATOM   4134 C  CA  . ASN B 2 390 ? 104.475 101.552 105.206 1.00 28.32  ? 390 ASN D CA  1 
ATOM   4135 C  C   . ASN B 2 390 ? 103.899 100.261 105.765 1.00 28.32  ? 390 ASN D C   1 
ATOM   4136 O  O   . ASN B 2 390 ? 102.765 100.226 106.251 1.00 28.32  ? 390 ASN D O   1 
ATOM   4137 C  CB  . ASN B 2 390 ? 105.579 102.073 106.132 1.00 28.32  ? 390 ASN D CB  1 
ATOM   4138 C  CG  . ASN B 2 390 ? 105.187 102.012 107.591 1.00 28.32  ? 390 ASN D CG  1 
ATOM   4139 O  OD1 . ASN B 2 390 ? 104.274 102.711 108.028 1.00 28.32  ? 390 ASN D OD1 1 
ATOM   4140 N  ND2 . ASN B 2 390 ? 105.876 101.175 108.355 1.00 28.32  ? 390 ASN D ND2 1 
ATOM   4141 N  N   . LYS B 2 391 ? 104.698 99.200  105.691 1.00 33.84  ? 391 LYS D N   1 
ATOM   4142 C  CA  . LYS B 2 391 ? 104.289 97.893  106.183 1.00 33.84  ? 391 LYS D CA  1 
ATOM   4143 C  C   . LYS B 2 391 ? 105.035 97.548  107.465 1.00 33.84  ? 391 LYS D C   1 
ATOM   4144 O  O   . LYS B 2 391 ? 106.246 97.760  107.573 1.00 33.84  ? 391 LYS D O   1 
ATOM   4145 C  CB  . LYS B 2 391 ? 104.558 96.820  105.130 1.00 33.84  ? 391 LYS D CB  1 
ATOM   4146 C  CG  . LYS B 2 391 ? 104.066 97.165  103.739 1.00 33.84  ? 391 LYS D CG  1 
ATOM   4147 C  CD  . LYS B 2 391 ? 104.648 96.212  102.709 1.00 33.84  ? 391 LYS D CD  1 
ATOM   4148 C  CE  . LYS B 2 391 ? 104.085 94.811  102.870 1.00 33.84  ? 391 LYS D CE  1 
ATOM   4149 N  NZ  . LYS B 2 391 ? 104.723 93.843  101.937 1.00 33.84  ? 391 LYS D NZ  1 
ATOM   4150 N  N   . GLY B 2 392 ? 104.305 97.008  108.439 1.00 35.01  ? 392 GLY D N   1 
ATOM   4151 C  CA  . GLY B 2 392 ? 104.929 96.575  109.669 1.00 35.01  ? 392 GLY D CA  1 
ATOM   4152 C  C   . GLY B 2 392 ? 105.768 95.327  109.482 1.00 35.01  ? 392 GLY D C   1 
ATOM   4153 O  O   . GLY B 2 392 ? 105.725 94.664  108.447 1.00 35.01  ? 392 GLY D O   1 
ATOM   4154 N  N   . ALA B 2 393 ? 106.552 95.004  110.508 1.00 39.11  ? 393 ALA D N   1 
ATOM   4155 C  CA  . ALA B 2 393 ? 107.430 93.847  110.455 1.00 39.11  ? 393 ALA D CA  1 
ATOM   4156 C  C   . ALA B 2 393 ? 107.781 93.392  111.863 1.00 39.11  ? 393 ALA D C   1 
ATOM   4157 O  O   . ALA B 2 393 ? 107.656 94.143  112.833 1.00 39.11  ? 393 ALA D O   1 
ATOM   4158 C  CB  . ALA B 2 393 ? 108.712 94.149  109.670 1.00 39.11  ? 393 ALA D CB  1 
ATOM   4159 N  N   . TYR B 2 394 ? 108.225 92.141  111.960 1.00 51.63  ? 394 TYR D N   1 
ATOM   4160 C  CA  . TYR B 2 394 ? 108.725 91.589  113.209 1.00 51.63  ? 394 TYR D CA  1 
ATOM   4161 C  C   . TYR B 2 394 ? 109.726 90.490  112.884 1.00 51.63  ? 394 TYR D C   1 
ATOM   4162 O  O   . TYR B 2 394 ? 109.727 89.930  111.786 1.00 51.63  ? 394 TYR D O   1 
ATOM   4163 C  CB  . TYR B 2 394 ? 107.584 91.078  114.103 1.00 51.63  ? 394 TYR D CB  1 
ATOM   4164 C  CG  . TYR B 2 394 ? 106.931 89.788  113.659 1.00 51.63  ? 394 TYR D CG  1 
ATOM   4165 C  CD1 . TYR B 2 394 ? 107.452 88.555  114.028 1.00 51.63  ? 394 TYR D CD1 1 
ATOM   4166 C  CD2 . TYR B 2 394 ? 105.777 89.805  112.888 1.00 51.63  ? 394 TYR D CD2 1 
ATOM   4167 C  CE1 . TYR B 2 394 ? 106.853 87.378  113.629 1.00 51.63  ? 394 TYR D CE1 1 
ATOM   4168 C  CE2 . TYR B 2 394 ? 105.171 88.632  112.485 1.00 51.63  ? 394 TYR D CE2 1 
ATOM   4169 C  CZ  . TYR B 2 394 ? 105.713 87.423  112.858 1.00 51.63  ? 394 TYR D CZ  1 
ATOM   4170 O  OH  . TYR B 2 394 ? 105.114 86.252  112.460 1.00 51.63  ? 394 TYR D OH  1 
ATOM   4171 N  N   . ILE B 2 395 ? 110.581 90.185  113.856 1.00 51.63  ? 395 ILE D N   1 
ATOM   4172 C  CA  . ILE B 2 395 ? 111.733 89.315  113.656 1.00 51.63  ? 395 ILE D CA  1 
ATOM   4173 C  C   . ILE B 2 395 ? 111.522 88.014  114.414 1.00 51.63  ? 395 ILE D C   1 
ATOM   4174 O  O   . ILE B 2 395 ? 111.123 88.021  115.584 1.00 51.63  ? 395 ILE D O   1 
ATOM   4175 C  CB  . ILE B 2 395 ? 113.035 90.005  114.108 1.00 51.63  ? 395 ILE D CB  1 
ATOM   4176 C  CG1 . ILE B 2 395 ? 113.571 90.909  113.002 1.00 51.63  ? 395 ILE D CG1 1 
ATOM   4177 C  CG2 . ILE B 2 395 ? 114.087 88.984  114.494 1.00 51.63  ? 395 ILE D CG2 1 
ATOM   4178 C  CD1 . ILE B 2 395 ? 114.753 91.738  113.427 1.00 51.63  ? 395 ILE D CD1 1 
ATOM   4179 N  N   . ARG B 2 396 ? 111.783 86.897  113.742 1.00 38.85  ? 396 ARG D N   1 
ATOM   4180 C  CA  . ARG B 2 396 ? 111.831 85.584  114.369 1.00 38.85  ? 396 ARG D CA  1 
ATOM   4181 C  C   . ARG B 2 396 ? 113.266 85.079  114.342 1.00 38.85  ? 396 ARG D C   1 
ATOM   4182 O  O   . ARG B 2 396 ? 113.871 84.981  113.270 1.00 38.85  ? 396 ARG D O   1 
ATOM   4183 C  CB  . ARG B 2 396 ? 110.910 84.594  113.655 1.00 38.85  ? 396 ARG D CB  1 
ATOM   4184 C  CG  . ARG B 2 396 ? 109.433 84.896  113.804 1.00 38.85  ? 396 ARG D CG  1 
ATOM   4185 C  CD  . ARG B 2 396 ? 108.596 83.899  113.019 1.00 38.85  ? 396 ARG D CD  1 
ATOM   4186 N  NE  . ARG B 2 396 ? 109.046 82.526  113.221 1.00 38.85  ? 396 ARG D NE  1 
ATOM   4187 C  CZ  . ARG B 2 396 ? 108.877 81.833  114.339 1.00 38.85  ? 396 ARG D CZ  1 
ATOM   4188 N  NH1 . ARG B 2 396 ? 108.255 82.349  115.386 1.00 38.85  ? 396 ARG D NH1 1 
ATOM   4189 N  NH2 . ARG B 2 396 ? 109.342 80.589  114.407 1.00 38.85  ? 396 ARG D NH2 1 
ATOM   4190 N  N   . LEU B 2 397 ? 113.803 84.758  115.513 1.00 29.36  ? 397 LEU D N   1 
ATOM   4191 C  CA  . LEU B 2 397 ? 115.182 84.311  115.651 1.00 29.36  ? 397 LEU D CA  1 
ATOM   4192 C  C   . LEU B 2 397 ? 115.207 82.843  116.048 1.00 29.36  ? 397 LEU D C   1 
ATOM   4193 O  O   . LEU B 2 397 ? 114.567 82.449  117.028 1.00 29.36  ? 397 LEU D O   1 
ATOM   4194 C  CB  . LEU B 2 397 ? 115.930 85.147  116.691 1.00 29.36  ? 397 LEU D CB  1 
ATOM   4195 C  CG  . LEU B 2 397 ? 116.108 86.638  116.405 1.00 29.36  ? 397 LEU D CG  1 
ATOM   4196 C  CD1 . LEU B 2 397 ? 116.539 87.373  117.660 1.00 29.36  ? 397 LEU D CD1 1 
ATOM   4197 C  CD2 . LEU B 2 397 ? 117.116 86.851  115.293 1.00 29.36  ? 397 LEU D CD2 1 
ATOM   4198 N  N   . ASN B 2 398 ? 115.945 82.040  115.288 1.00 39.77  ? 398 ASN D N   1 
ATOM   4199 C  CA  . ASN B 2 398 ? 116.130 80.637  115.618 1.00 39.77  ? 398 ASN D CA  1 
ATOM   4200 C  C   . ASN B 2 398 ? 117.290 80.489  116.603 1.00 39.77  ? 398 ASN D C   1 
ATOM   4201 O  O   . ASN B 2 398 ? 117.884 81.471  117.056 1.00 39.77  ? 398 ASN D O   1 
ATOM   4202 C  CB  . ASN B 2 398 ? 116.326 79.824  114.336 1.00 39.77  ? 398 ASN D CB  1 
ATOM   4203 C  CG  . ASN B 2 398 ? 117.788 79.603  113.985 1.00 39.77  ? 398 ASN D CG  1 
ATOM   4204 O  OD1 . ASN B 2 398 ? 118.478 78.797  114.610 1.00 39.77  ? 398 ASN D OD1 1 
ATOM   4205 N  ND2 . ASN B 2 398 ? 118.264 80.318  112.973 1.00 39.77  ? 398 ASN D ND2 1 
ATOM   4206 N  N   . ASN B 2 399 ? 117.614 79.240  116.948 1.00 44.23  ? 399 ASN D N   1 
ATOM   4207 C  CA  . ASN B 2 399 ? 118.676 78.981  117.913 1.00 44.23  ? 399 ASN D CA  1 
ATOM   4208 C  C   . ASN B 2 399 ? 120.028 79.505  117.447 1.00 44.23  ? 399 ASN D C   1 
ATOM   4209 O  O   . ASN B 2 399 ? 120.887 79.802  118.285 1.00 44.23  ? 399 ASN D O   1 
ATOM   4210 C  CB  . ASN B 2 399 ? 118.769 77.482  118.200 1.00 44.23  ? 399 ASN D CB  1 
ATOM   4211 C  CG  . ASN B 2 399 ? 119.750 77.161  119.307 1.00 44.23  ? 399 ASN D CG  1 
ATOM   4212 O  OD1 . ASN B 2 399 ? 119.755 77.810  120.353 1.00 44.23  ? 399 ASN D OD1 1 
ATOM   4213 N  ND2 . ASN B 2 399 ? 120.587 76.156  119.084 1.00 44.23  ? 399 ASN D ND2 1 
ATOM   4214 N  N   . GLN B 2 400 ? 120.238 79.628  116.140 1.00 48.06  ? 400 GLN D N   1 
ATOM   4215 C  CA  . GLN B 2 400 ? 121.466 80.193  115.598 1.00 48.06  ? 400 GLN D CA  1 
ATOM   4216 C  C   . GLN B 2 400 ? 121.375 81.698  115.384 1.00 48.06  ? 400 GLN D C   1 
ATOM   4217 O  O   . GLN B 2 400 ? 122.315 82.289  114.841 1.00 48.06  ? 400 GLN D O   1 
ATOM   4218 C  CB  . GLN B 2 400 ? 121.830 79.504  114.279 1.00 48.06  ? 400 GLN D CB  1 
ATOM   4219 C  CG  . GLN B 2 400 ? 121.935 77.990  114.374 1.00 48.06  ? 400 GLN D CG  1 
ATOM   4220 C  CD  . GLN B 2 400 ? 123.116 77.533  115.211 1.00 48.06  ? 400 GLN D CD  1 
ATOM   4221 O  OE1 . GLN B 2 400 ? 124.037 78.303  115.481 1.00 48.06  ? 400 GLN D OE1 1 
ATOM   4222 N  NE2 . GLN B 2 400 ? 123.092 76.271  115.624 1.00 48.06  ? 400 GLN D NE2 1 
ATOM   4223 N  N   . LEU B 2 401 ? 120.267 82.322  115.789 1.00 41.32  ? 401 LEU D N   1 
ATOM   4224 C  CA  . LEU B 2 401 ? 120.070 83.768  115.686 1.00 41.32  ? 401 LEU D CA  1 
ATOM   4225 C  C   . LEU B 2 401 ? 120.136 84.261  114.242 1.00 41.32  ? 401 LEU D C   1 
ATOM   4226 O  O   . LEU B 2 401 ? 120.730 85.303  113.957 1.00 41.32  ? 401 LEU D O   1 
ATOM   4227 C  CB  . LEU B 2 401 ? 121.072 84.528  116.560 1.00 41.32  ? 401 LEU D CB  1 
ATOM   4228 C  CG  . LEU B 2 401 ? 121.069 84.126  118.035 1.00 41.32  ? 401 LEU D CG  1 
ATOM   4229 C  CD1 . LEU B 2 401 ? 122.071 84.949  118.821 1.00 41.32  ? 401 LEU D CD1 1 
ATOM   4230 C  CD2 . LEU B 2 401 ? 119.676 84.275  118.619 1.00 41.32  ? 401 LEU D CD2 1 
ATOM   4231 N  N   . MET B 2 402 ? 119.532 83.519  113.323 1.00 48.06  ? 402 MET D N   1 
ATOM   4232 C  CA  . MET B 2 402 ? 119.371 84.010  111.960 1.00 48.06  ? 402 MET D CA  1 
ATOM   4233 C  C   . MET B 2 402 ? 118.019 84.701  111.827 1.00 48.06  ? 402 MET D C   1 
ATOM   4234 O  O   . MET B 2 402 ? 116.981 84.053  111.986 1.00 48.06  ? 402 MET D O   1 
ATOM   4235 C  CB  . MET B 2 402 ? 119.481 82.868  110.956 1.00 48.06  ? 402 MET D CB  1 
ATOM   4236 C  CG  . MET B 2 402 ? 120.699 81.982  111.158 1.00 48.06  ? 402 MET D CG  1 
ATOM   4237 S  SD  . MET B 2 402 ? 120.575 80.405  110.293 1.00 48.06  ? 402 MET D SD  1 
ATOM   4238 C  CE  . MET B 2 402 ? 119.542 80.855  108.902 1.00 48.06  ? 402 MET D CE  1 
ATOM   4239 N  N   . PRO B 2 403 ? 117.988 85.998  111.536 1.00 44.33  ? 403 PRO D N   1 
ATOM   4240 C  CA  . PRO B 2 403 ? 116.721 86.738  111.602 1.00 44.33  ? 403 PRO D CA  1 
ATOM   4241 C  C   . PRO B 2 403 ? 115.787 86.490  110.427 1.00 44.33  ? 403 PRO D C   1 
ATOM   4242 O  O   . PRO B 2 403 ? 116.059 86.925  109.304 1.00 44.33  ? 403 PRO D O   1 
ATOM   4243 C  CB  . PRO B 2 403 ? 117.182 88.199  111.644 1.00 44.33  ? 403 PRO D CB  1 
ATOM   4244 C  CG  . PRO B 2 403 ? 118.485 88.195  110.929 1.00 44.33  ? 403 PRO D CG  1 
ATOM   4245 C  CD  . PRO B 2 403 ? 119.131 86.872  111.229 1.00 44.33  ? 403 PRO D CD  1 
ATOM   4246 N  N   . HIS B 2 404 ? 114.674 85.805  110.680 1.00 47.41  ? 404 HIS D N   1 
ATOM   4247 C  CA  . HIS B 2 404 ? 113.620 85.661  109.684 1.00 47.41  ? 404 HIS D CA  1 
ATOM   4248 C  C   . HIS B 2 404 ? 112.636 86.816  109.814 1.00 47.41  ? 404 HIS D C   1 
ATOM   4249 O  O   . HIS B 2 404 ? 112.119 87.081  110.903 1.00 47.41  ? 404 HIS D O   1 
ATOM   4250 C  CB  . HIS B 2 404 ? 112.893 84.329  109.855 1.00 47.41  ? 404 HIS D CB  1 
ATOM   4251 C  CG  . HIS B 2 404 ? 113.724 83.135  109.504 1.00 47.41  ? 404 HIS D CG  1 
ATOM   4252 N  ND1 . HIS B 2 404 ? 113.921 82.722  108.204 1.00 47.41  ? 404 HIS D ND1 1 
ATOM   4253 C  CD2 . HIS B 2 404 ? 114.405 82.263  110.283 1.00 47.41  ? 404 HIS D CD2 1 
ATOM   4254 C  CE1 . HIS B 2 404 ? 114.689 81.648  108.197 1.00 47.41  ? 404 HIS D CE1 1 
ATOM   4255 N  NE2 . HIS B 2 404 ? 114.997 81.349  109.446 1.00 47.41  ? 404 HIS D NE2 1 
ATOM   4256 N  N   . PHE B 2 405 ? 112.371 87.497  108.705 1.00 51.63  ? 405 PHE D N   1 
ATOM   4257 C  CA  . PHE B 2 405 ? 111.545 88.696  108.707 1.00 51.63  ? 405 PHE D CA  1 
ATOM   4258 C  C   . PHE B 2 405 ? 110.163 88.394  108.144 1.00 51.63  ? 405 PHE D C   1 
ATOM   4259 O  O   . PHE B 2 405 ? 110.028 87.675  107.151 1.00 51.63  ? 405 PHE D O   1 
ATOM   4260 C  CB  . PHE B 2 405 ? 112.202 89.811  107.893 1.00 51.63  ? 405 PHE D CB  1 
ATOM   4261 C  CG  . PHE B 2 405 ? 113.447 90.367  108.519 1.00 51.63  ? 405 PHE D CG  1 
ATOM   4262 C  CD1 . PHE B 2 405 ? 114.634 89.656  108.488 1.00 51.63  ? 405 PHE D CD1 1 
ATOM   4263 C  CD2 . PHE B 2 405 ? 113.431 91.601  109.141 1.00 51.63  ? 405 PHE D CD2 1 
ATOM   4264 C  CE1 . PHE B 2 405 ? 115.776 90.167  109.063 1.00 51.63  ? 405 PHE D CE1 1 
ATOM   4265 C  CE2 . PHE B 2 405 ? 114.571 92.116  109.717 1.00 51.63  ? 405 PHE D CE2 1 
ATOM   4266 C  CZ  . PHE B 2 405 ? 115.745 91.397  109.679 1.00 51.63  ? 405 PHE D CZ  1 
ATOM   4267 N  N   . VAL B 2 406 ? 109.141 88.950  108.787 1.00 47.16  ? 406 VAL D N   1 
ATOM   4268 C  CA  . VAL B 2 406 ? 107.757 88.821  108.351 1.00 47.16  ? 406 VAL D CA  1 
ATOM   4269 C  C   . VAL B 2 406 ? 107.193 90.221  108.160 1.00 47.16  ? 406 VAL D C   1 
ATOM   4270 O  O   . VAL B 2 406 ? 107.642 91.179  108.795 1.00 47.16  ? 406 VAL D O   1 
ATOM   4271 C  CB  . VAL B 2 406 ? 106.910 88.016  109.363 1.00 47.16  ? 406 VAL D CB  1 
ATOM   4272 C  CG1 . VAL B 2 406 ? 105.564 87.640  108.768 1.00 47.16  ? 406 VAL D CG1 1 
ATOM   4273 C  CG2 . VAL B 2 406 ? 107.657 86.774  109.815 1.00 47.16  ? 406 VAL D CG2 1 
ATOM   4274 N  N   . GLN B 2 407 ? 106.210 90.342  107.271 1.00 40.44  ? 407 GLN D N   1 
ATOM   4275 C  CA  . GLN B 2 407 ? 105.566 91.615  106.985 1.00 40.44  ? 407 GLN D CA  1 
ATOM   4276 C  C   . GLN B 2 407 ? 104.054 91.446  106.998 1.00 40.44  ? 407 GLN D C   1 
ATOM   4277 O  O   . GLN B 2 407 ? 103.534 90.353  106.759 1.00 40.44  ? 407 GLN D O   1 
ATOM   4278 C  CB  . GLN B 2 407 ? 106.010 92.174  105.630 1.00 40.44  ? 407 GLN D CB  1 
ATOM   4279 C  CG  . GLN B 2 407 ? 107.485 92.511  105.547 1.00 40.44  ? 407 GLN D CG  1 
ATOM   4280 C  CD  . GLN B 2 407 ? 107.857 93.147  104.225 1.00 40.44  ? 407 GLN D CD  1 
ATOM   4281 O  OE1 . GLN B 2 407 ? 107.049 93.193  103.297 1.00 40.44  ? 407 GLN D OE1 1 
ATOM   4282 N  NE2 . GLN B 2 407 ? 109.081 93.649  104.133 1.00 40.44  ? 407 GLN D NE2 1 
ATOM   4283 N  N   . TYR B 2 408 ? 103.349 92.540  107.283 1.00 42.40  ? 408 TYR D N   1 
ATOM   4284 C  CA  . TYR B 2 408 ? 101.895 92.517  107.313 1.00 42.40  ? 408 TYR D CA  1 
ATOM   4285 C  C   . TYR B 2 408 ? 101.358 93.935  107.189 1.00 42.40  ? 408 TYR D C   1 
ATOM   4286 O  O   . TYR B 2 408 ? 102.001 94.903  107.602 1.00 42.40  ? 408 TYR D O   1 
ATOM   4287 C  CB  . TYR B 2 408 ? 101.371 91.854  108.595 1.00 42.40  ? 408 TYR D CB  1 
ATOM   4288 C  CG  . TYR B 2 408 ? 101.908 92.461  109.871 1.00 42.40  ? 408 TYR D CG  1 
ATOM   4289 C  CD1 . TYR B 2 408 ? 101.350 93.614  110.405 1.00 42.40  ? 408 TYR D CD1 1 
ATOM   4290 C  CD2 . TYR B 2 408 ? 102.974 91.880  110.541 1.00 42.40  ? 408 TYR D CD2 1 
ATOM   4291 C  CE1 . TYR B 2 408 ? 101.837 94.171  111.566 1.00 42.40  ? 408 TYR D CE1 1 
ATOM   4292 C  CE2 . TYR B 2 408 ? 103.469 92.431  111.705 1.00 42.40  ? 408 TYR D CE2 1 
ATOM   4293 C  CZ  . TYR B 2 408 ? 102.896 93.576  112.212 1.00 42.40  ? 408 TYR D CZ  1 
ATOM   4294 O  OH  . TYR B 2 408 ? 103.384 94.131  113.372 1.00 42.40  ? 408 TYR D OH  1 
ATOM   4295 N  N   . ILE B 2 409 ? 100.165 94.045  106.607 1.00 52.25  ? 409 ILE D N   1 
ATOM   4296 C  CA  . ILE B 2 409 ? 99.428  95.301  106.525 1.00 52.25  ? 409 ILE D CA  1 
ATOM   4297 C  C   . ILE B 2 409 ? 98.025  95.056  107.056 1.00 52.25  ? 409 ILE D C   1 
ATOM   4298 O  O   . ILE B 2 409 ? 97.346  94.124  106.614 1.00 52.25  ? 409 ILE D O   1 
ATOM   4299 C  CB  . ILE B 2 409 ? 99.361  95.848  105.087 1.00 52.25  ? 409 ILE D CB  1 
ATOM   4300 C  CG1 . ILE B 2 409 ? 100.712 95.716  104.385 1.00 52.25  ? 409 ILE D CG1 1 
ATOM   4301 C  CG2 . ILE B 2 409 ? 98.904  97.297  105.092 1.00 52.25  ? 409 ILE D CG2 1 
ATOM   4302 C  CD1 . ILE B 2 409 ? 100.669 96.107  102.925 1.00 52.25  ? 409 ILE D CD1 1 
ATOM   4303 N  N   . SER B 2 410 ? 97.586  95.894  107.991 1.00 57.72  ? 410 SER D N   1 
ATOM   4304 C  CA  . SER B 2 410 ? 96.267  95.746  108.582 1.00 57.72  ? 410 SER D CA  1 
ATOM   4305 C  C   . SER B 2 410 ? 95.229  96.516  107.767 1.00 57.72  ? 410 SER D C   1 
ATOM   4306 O  O   . SER B 2 410 ? 95.558  97.370  106.940 1.00 57.72  ? 410 SER D O   1 
ATOM   4307 C  CB  . SER B 2 410 ? 96.283  96.210  110.037 1.00 57.72  ? 410 SER D CB  1 
ATOM   4308 O  OG  . SER B 2 410 ? 96.363  97.622  110.119 1.00 57.72  ? 410 SER D OG  1 
ATOM   4309 N  N   . ALA B 2 411 ? 93.953  96.201  108.007 1.00 81.47  ? 411 ALA D N   1 
ATOM   4310 C  CA  . ALA B 2 411 ? 92.822  96.843  107.330 1.00 81.47  ? 411 ALA D CA  1 
ATOM   4311 C  C   . ALA B 2 411 ? 92.912  96.711  105.811 1.00 81.47  ? 411 ALA D C   1 
ATOM   4312 O  O   . ALA B 2 411 ? 92.875  97.709  105.087 1.00 81.47  ? 411 ALA D O   1 
ATOM   4313 C  CB  . ALA B 2 411 ? 92.695  98.317  107.731 1.00 81.47  ? 411 ALA D CB  1 
ATOM   4314 N  N   . ALA B 2 412 ? 93.031  95.476  105.318 1.00 100.60 ? 412 ALA D N   1 
ATOM   4315 C  CA  . ALA B 2 412 ? 93.147  95.262  103.879 1.00 100.60 ? 412 ALA D CA  1 
ATOM   4316 C  C   . ALA B 2 412 ? 91.798  95.404  103.182 1.00 100.60 ? 412 ALA D C   1 
ATOM   4317 O  O   . ALA B 2 412 ? 91.738  95.764  101.999 1.00 100.60 ? 412 ALA D O   1 
ATOM   4318 C  CB  . ALA B 2 412 ? 93.753  93.887  103.601 1.00 100.60 ? 412 ALA D CB  1 
ATOM   4319 N  N   . SER B 2 413 ? 90.704  95.113  103.893 1.00 107.74 ? 413 SER D N   1 
ATOM   4320 C  CA  . SER B 2 413 ? 89.382  95.173  103.276 1.00 107.74 ? 413 SER D CA  1 
ATOM   4321 C  C   . SER B 2 413 ? 89.032  96.583  102.821 1.00 107.74 ? 413 SER D C   1 
ATOM   4322 O  O   . SER B 2 413 ? 88.492  96.763  101.724 1.00 107.74 ? 413 SER D O   1 
ATOM   4323 C  CB  . SER B 2 413 ? 88.321  94.653  104.246 1.00 107.74 ? 413 SER D CB  1 
ATOM   4324 O  OG  . SER B 2 413 ? 88.252  95.463  105.406 1.00 107.74 ? 413 SER D OG  1 
ATOM   4325 N  N   . GLN B 2 414 ? 89.324  97.591  103.643 1.00 103.67 ? 414 GLN D N   1 
ATOM   4326 C  CA  . GLN B 2 414 ? 89.060  98.966  103.236 1.00 103.67 ? 414 GLN D CA  1 
ATOM   4327 C  C   . GLN B 2 414 ? 90.069  99.442  102.199 1.00 103.67 ? 414 GLN D C   1 
ATOM   4328 O  O   . GLN B 2 414 ? 89.765  100.330 101.394 1.00 103.67 ? 414 GLN D O   1 
ATOM   4329 C  CB  . GLN B 2 414 ? 89.070  99.887  104.456 1.00 103.67 ? 414 GLN D CB  1 
ATOM   4330 C  CG  . GLN B 2 414 ? 87.902  99.671  105.404 1.00 103.67 ? 414 GLN D CG  1 
ATOM   4331 C  CD  . GLN B 2 414 ? 87.792  100.762 106.450 1.00 103.67 ? 414 GLN D CD  1 
ATOM   4332 O  OE1 . GLN B 2 414 ? 88.797  101.225 106.988 1.00 103.67 ? 414 GLN D OE1 1 
ATOM   4333 N  NE2 . GLN B 2 414 ? 86.566  101.179 106.743 1.00 103.67 ? 414 GLN D NE2 1 
ATOM   4334 N  N   . THR B 2 415 ? 91.273  98.865  102.204 1.00 104.56 ? 415 THR D N   1 
ATOM   4335 C  CA  . THR B 2 415 ? 92.289  99.257  101.234 1.00 104.56 ? 415 THR D CA  1 
ATOM   4336 C  C   . THR B 2 415 ? 91.967  98.736  99.839  1.00 104.56 ? 415 THR D C   1 
ATOM   4337 O  O   . THR B 2 415 ? 92.284  99.394  98.842  1.00 104.56 ? 415 THR D O   1 
ATOM   4338 C  CB  . THR B 2 415 ? 93.663  98.757  101.684 1.00 104.56 ? 415 THR D CB  1 
ATOM   4339 O  OG1 . THR B 2 415 ? 93.871  99.102  103.060 1.00 104.56 ? 415 THR D OG1 1 
ATOM   4340 C  CG2 . THR B 2 415 ? 94.766  99.384  100.843 1.00 104.56 ? 415 THR D CG2 1 
ATOM   4341 N  N   . LYS B 2 416 ? 91.333  97.567  99.745  1.00 109.46 ? 416 LYS D N   1 
ATOM   4342 C  CA  . LYS B 2 416 ? 91.057  96.949  98.453  1.00 109.46 ? 416 LYS D CA  1 
ATOM   4343 C  C   . LYS B 2 416 ? 89.857  97.557  97.736  1.00 109.46 ? 416 LYS D C   1 
ATOM   4344 O  O   . LYS B 2 416 ? 89.590  97.181  96.590  1.00 109.46 ? 416 LYS D O   1 
ATOM   4345 C  CB  . LYS B 2 416 ? 90.840  95.443  98.624  1.00 109.46 ? 416 LYS D CB  1 
ATOM   4346 C  CG  . LYS B 2 416 ? 89.489  95.071  99.210  1.00 109.46 ? 416 LYS D CG  1 
ATOM   4347 C  CD  . LYS B 2 416 ? 89.379  93.573  99.447  1.00 109.46 ? 416 LYS D CD  1 
ATOM   4348 C  CE  . LYS B 2 416 ? 89.393  92.805  98.136  1.00 109.46 ? 416 LYS D CE  1 
ATOM   4349 N  NZ  . LYS B 2 416 ? 89.241  91.339  98.350  1.00 109.46 ? 416 LYS D NZ  1 
ATOM   4350 N  N   . ARG B 2 417 ? 89.128  98.476  98.370  1.00 109.93 ? 417 ARG D N   1 
ATOM   4351 C  CA  . ARG B 2 417 ? 87.965  99.106  97.761  1.00 109.93 ? 417 ARG D CA  1 
ATOM   4352 C  C   . ARG B 2 417 ? 88.307  100.391 97.015  1.00 109.93 ? 417 ARG D C   1 
ATOM   4353 O  O   . ARG B 2 417 ? 87.422  101.228 96.804  1.00 109.93 ? 417 ARG D O   1 
ATOM   4354 C  CB  . ARG B 2 417 ? 86.901  99.395  98.823  1.00 109.93 ? 417 ARG D CB  1 
ATOM   4355 C  CG  . ARG B 2 417 ? 86.525  98.202  99.681  1.00 109.93 ? 417 ARG D CG  1 
ATOM   4356 C  CD  . ARG B 2 417 ? 85.545  98.607  100.769 1.00 109.93 ? 417 ARG D CD  1 
ATOM   4357 N  NE  . ARG B 2 417 ? 85.363  97.557  101.764 1.00 109.93 ? 417 ARG D NE  1 
ATOM   4358 C  CZ  . ARG B 2 417 ? 84.483  97.609  102.755 1.00 109.93 ? 417 ARG D CZ  1 
ATOM   4359 N  NH1 . ARG B 2 417 ? 83.685  98.652  102.916 1.00 109.93 ? 417 ARG D NH1 1 
ATOM   4360 N  NH2 . ARG B 2 417 ? 84.403  96.590  103.606 1.00 109.93 ? 417 ARG D NH2 1 
ATOM   4361 N  N   . LEU B 2 418 ? 89.564  100.570 96.613  1.00 98.01  ? 418 LEU D N   1 
ATOM   4362 C  CA  . LEU B 2 418 ? 89.979  101.771 95.906  1.00 98.01  ? 418 LEU D CA  1 
ATOM   4363 C  C   . LEU B 2 418 ? 90.895  101.397 94.752  1.00 98.01  ? 418 LEU D C   1 
ATOM   4364 O  O   . LEU B 2 418 ? 91.546  100.349 94.767  1.00 98.01  ? 418 LEU D O   1 
ATOM   4365 C  CB  . LEU B 2 418 ? 90.697  102.761 96.834  1.00 98.01  ? 418 LEU D CB  1 
ATOM   4366 C  CG  . LEU B 2 418 ? 89.854  103.440 97.915  1.00 98.01  ? 418 LEU D CG  1 
ATOM   4367 C  CD1 . LEU B 2 418 ? 90.026  102.737 99.250  1.00 98.01  ? 418 LEU D CD1 1 
ATOM   4368 C  CD2 . LEU B 2 418 ? 90.218  104.912 98.030  1.00 98.01  ? 418 LEU D CD2 1 
ATOM   4369 N  N   . SER B 2 419 ? 90.934  102.267 93.747  1.00 90.62  ? 419 SER D N   1 
ATOM   4370 C  CA  . SER B 2 419 ? 91.869  102.097 92.647  1.00 90.62  ? 419 SER D CA  1 
ATOM   4371 C  C   . SER B 2 419 ? 93.270  102.518 93.076  1.00 90.62  ? 419 SER D C   1 
ATOM   4372 O  O   . SER B 2 419 ? 93.462  103.143 94.122  1.00 90.62  ? 419 SER D O   1 
ATOM   4373 C  CB  . SER B 2 419 ? 91.422  102.912 91.434  1.00 90.62  ? 419 SER D CB  1 
ATOM   4374 O  OG  . SER B 2 419 ? 92.511  103.165 90.563  1.00 90.62  ? 419 SER D OG  1 
ATOM   4375 N  N   . PHE B 2 420 ? 94.258  102.160 92.253  1.00 89.72  ? 420 PHE D N   1 
ATOM   4376 C  CA  . PHE B 2 420 ? 95.642  102.492 92.573  1.00 89.72  ? 420 PHE D CA  1 
ATOM   4377 C  C   . PHE B 2 420 ? 95.849  104.002 92.606  1.00 89.72  ? 420 PHE D C   1 
ATOM   4378 O  O   . PHE B 2 420 ? 96.553  104.525 93.482  1.00 89.72  ? 420 PHE D O   1 
ATOM   4379 C  CB  . PHE B 2 420 ? 96.578  101.833 91.558  1.00 89.72  ? 420 PHE D CB  1 
ATOM   4380 C  CG  . PHE B 2 420 ? 98.023  102.205 91.728  1.00 89.72  ? 420 PHE D CG  1 
ATOM   4381 C  CD1 . PHE B 2 420 ? 98.604  102.232 92.985  1.00 89.72  ? 420 PHE D CD1 1 
ATOM   4382 C  CD2 . PHE B 2 420 ? 98.805  102.517 90.628  1.00 89.72  ? 420 PHE D CD2 1 
ATOM   4383 C  CE1 . PHE B 2 420 ? 99.932  102.569 93.143  1.00 89.72  ? 420 PHE D CE1 1 
ATOM   4384 C  CE2 . PHE B 2 420 ? 100.134 102.855 90.780  1.00 89.72  ? 420 PHE D CE2 1 
ATOM   4385 C  CZ  . PHE B 2 420 ? 100.698 102.880 92.039  1.00 89.72  ? 420 PHE D CZ  1 
ATOM   4386 N  N   . LYS B 2 421 ? 95.236  104.721 91.662  1.00 91.88  ? 421 LYS D N   1 
ATOM   4387 C  CA  . LYS B 2 421 ? 95.351  106.175 91.647  1.00 91.88  ? 421 LYS D CA  1 
ATOM   4388 C  C   . LYS B 2 421 ? 94.778  106.787 92.918  1.00 91.88  ? 421 LYS D C   1 
ATOM   4389 O  O   . LYS B 2 421 ? 95.376  107.698 93.497  1.00 91.88  ? 421 LYS D O   1 
ATOM   4390 C  CB  . LYS B 2 421 ? 94.656  106.749 90.413  1.00 91.88  ? 421 LYS D CB  1 
ATOM   4391 C  CG  . LYS B 2 421 ? 95.148  108.134 90.022  1.00 91.88  ? 421 LYS D CG  1 
ATOM   4392 C  CD  . LYS B 2 421 ? 94.562  108.583 88.694  1.00 91.88  ? 421 LYS D CD  1 
ATOM   4393 C  CE  . LYS B 2 421 ? 95.302  109.793 88.146  1.00 91.88  ? 421 LYS D CE  1 
ATOM   4394 N  NZ  . LYS B 2 421 ? 94.758  110.233 86.832  1.00 91.88  ? 421 LYS D NZ  1 
ATOM   4395 N  N   . GLN B 2 422 ? 93.622  106.297 93.372  1.00 83.80  ? 422 GLN D N   1 
ATOM   4396 C  CA  . GLN B 2 422 ? 93.051  106.799 94.620  1.00 83.80  ? 422 GLN D CA  1 
ATOM   4397 C  C   . GLN B 2 422 ? 93.915  106.417 95.817  1.00 83.80  ? 422 GLN D C   1 
ATOM   4398 O  O   . GLN B 2 422 ? 94.033  107.188 96.779  1.00 83.80  ? 422 GLN D O   1 
ATOM   4399 C  CB  . GLN B 2 422 ? 91.628  106.272 94.792  1.00 83.80  ? 422 GLN D CB  1 
ATOM   4400 C  CG  . GLN B 2 422 ? 90.665  106.723 93.706  1.00 83.80  ? 422 GLN D CG  1 
ATOM   4401 C  CD  . GLN B 2 422 ? 89.364  105.944 93.719  1.00 83.80  ? 422 GLN D CD  1 
ATOM   4402 O  OE1 . GLN B 2 422 ? 89.359  104.720 93.582  1.00 83.80  ? 422 GLN D OE1 1 
ATOM   4403 N  NE2 . GLN B 2 422 ? 88.252  106.650 93.886  1.00 83.80  ? 422 GLN D NE2 1 
ATOM   4404 N  N   . ARG B 2 423 ? 94.523  105.228 95.776  1.00 82.80  ? 423 ARG D N   1 
ATOM   4405 C  CA  . ARG B 2 423 ? 95.389  104.798 96.869  1.00 82.80  ? 423 ARG D CA  1 
ATOM   4406 C  C   . ARG B 2 423 ? 96.622  105.686 96.981  1.00 82.80  ? 423 ARG D C   1 
ATOM   4407 O  O   . ARG B 2 423 ? 97.139  105.908 98.082  1.00 82.80  ? 423 ARG D O   1 
ATOM   4408 C  CB  . ARG B 2 423 ? 95.795  103.337 96.676  1.00 82.80  ? 423 ARG D CB  1 
ATOM   4409 C  CG  . ARG B 2 423 ? 94.829  102.339 97.294  1.00 82.80  ? 423 ARG D CG  1 
ATOM   4410 C  CD  . ARG B 2 423 ? 95.499  100.996 97.529  1.00 82.80  ? 423 ARG D CD  1 
ATOM   4411 N  NE  . ARG B 2 423 ? 95.817  100.318 96.278  1.00 82.80  ? 423 ARG D NE  1 
ATOM   4412 C  CZ  . ARG B 2 423 ? 95.024  99.441  95.677  1.00 82.80  ? 423 ARG D CZ  1 
ATOM   4413 N  NH1 . ARG B 2 423 ? 93.849  99.107  96.189  1.00 82.80  ? 423 ARG D NH1 1 
ATOM   4414 N  NH2 . ARG B 2 423 ? 95.418  98.885  94.535  1.00 82.80  ? 423 ARG D NH2 1 
ATOM   4415 N  N   . MET B 2 424 ? 97.124  106.185 95.850  1.00 72.77  ? 424 MET D N   1 
ATOM   4416 C  CA  . MET B 2 424 ? 98.209  107.161 95.913  1.00 72.77  ? 424 MET D CA  1 
ATOM   4417 C  C   . MET B 2 424 ? 97.690  108.540 96.304  1.00 72.77  ? 424 MET D C   1 
ATOM   4418 O  O   . MET B 2 424 ? 98.370  109.292 97.017  1.00 72.77  ? 424 MET D O   1 
ATOM   4419 C  CB  . MET B 2 424 ? 98.943  107.223 94.571  1.00 72.77  ? 424 MET D CB  1 
ATOM   4420 C  CG  . MET B 2 424 ? 100.393 107.741 94.610  1.00 72.77  ? 424 MET D CG  1 
ATOM   4421 S  SD  . MET B 2 424 ? 101.683 107.082 95.714  1.00 72.77  ? 424 MET D SD  1 
ATOM   4422 C  CE  . MET B 2 424 ? 101.050 105.522 96.337  1.00 72.77  ? 424 MET D CE  1 
ATOM   4423 N  N   . GLY B 2 425 ? 96.487  108.886 95.844  1.00 64.72  ? 425 GLY D N   1 
ATOM   4424 C  CA  . GLY B 2 425 ? 95.955  110.213 96.094  1.00 64.72  ? 425 GLY D CA  1 
ATOM   4425 C  C   . GLY B 2 425 ? 95.655  110.465 97.557  1.00 64.72  ? 425 GLY D C   1 
ATOM   4426 O  O   . GLY B 2 425 ? 95.824  111.581 98.046  1.00 64.72  ? 425 GLY D O   1 
ATOM   4427 N  N   . ILE B 2 426 ? 95.191  109.437 98.273  1.00 53.88  ? 426 ILE D N   1 
ATOM   4428 C  CA  . ILE B 2 426 ? 94.917  109.626 99.696  1.00 53.88  ? 426 ILE D CA  1 
ATOM   4429 C  C   . ILE B 2 426 ? 96.200  109.953 100.455 1.00 53.88  ? 426 ILE D C   1 
ATOM   4430 O  O   . ILE B 2 426 ? 96.226  110.879 101.279 1.00 53.88  ? 426 ILE D O   1 
ATOM   4431 C  CB  . ILE B 2 426 ? 94.199  108.395 100.283 1.00 53.88  ? 426 ILE D CB  1 
ATOM   4432 C  CG1 . ILE B 2 426 ? 94.059  108.529 101.800 1.00 53.88  ? 426 ILE D CG1 1 
ATOM   4433 C  CG2 . ILE B 2 426 ? 94.925  107.112 99.927  1.00 53.88  ? 426 ILE D CG2 1 
ATOM   4434 C  CD1 . ILE B 2 426 ? 93.335  107.370 102.446 1.00 53.88  ? 426 ILE D CD1 1 
ATOM   4435 N  N   . VAL B 2 427 ? 97.286  109.228 100.177 1.00 48.15  ? 427 VAL D N   1 
ATOM   4436 C  CA  . VAL B 2 427 ? 98.560  109.504 100.833 1.00 48.15  ? 427 VAL D CA  1 
ATOM   4437 C  C   . VAL B 2 427 ? 99.072  110.884 100.444 1.00 48.15  ? 427 VAL D C   1 
ATOM   4438 O  O   . VAL B 2 427 ? 99.574  111.639 101.286 1.00 48.15  ? 427 VAL D O   1 
ATOM   4439 C  CB  . VAL B 2 427 ? 99.586  108.407 100.495 1.00 48.15  ? 427 VAL D CB  1 
ATOM   4440 C  CG1 . VAL B 2 427 ? 100.915 108.693 101.173 1.00 48.15  ? 427 VAL D CG1 1 
ATOM   4441 C  CG2 . VAL B 2 427 ? 99.056  107.046 100.904 1.00 48.15  ? 427 VAL D CG2 1 
ATOM   4442 N  N   . GLU B 2 428 ? 98.960  111.233 99.159  1.00 50.67  ? 428 GLU D N   1 
ATOM   4443 C  CA  . GLU B 2 428 ? 99.428  112.538 98.705  1.00 50.67  ? 428 GLU D CA  1 
ATOM   4444 C  C   . GLU B 2 428 ? 98.661  113.666 99.387  1.00 50.67  ? 428 GLU D C   1 
ATOM   4445 O  O   . GLU B 2 428 ? 99.251  114.662 99.823  1.00 50.67  ? 428 GLU D O   1 
ATOM   4446 C  CB  . GLU B 2 428 ? 99.298  112.639 97.185  1.00 50.67  ? 428 GLU D CB  1 
ATOM   4447 C  CG  . GLU B 2 428 ? 99.681  113.995 96.621  1.00 50.67  ? 428 GLU D CG  1 
ATOM   4448 C  CD  . GLU B 2 428 ? 101.181 114.180 96.530  1.00 50.67  ? 428 GLU D CD  1 
ATOM   4449 O  OE1 . GLU B 2 428 ? 101.907 113.164 96.515  1.00 50.67  ? 428 GLU D OE1 1 
ATOM   4450 O  OE2 . GLU B 2 428 ? 101.636 115.341 96.474  1.00 50.67  ? 428 GLU D OE2 1 
ATOM   4451 N  N   . SER B 2 429 ? 97.338  113.520 99.491  1.00 47.97  ? 429 SER D N   1 
ATOM   4452 C  CA  . SER B 2 429 ? 96.524  114.533 100.150 1.00 47.97  ? 429 SER D CA  1 
ATOM   4453 C  C   . SER B 2 429 ? 96.852  114.640 101.631 1.00 47.97  ? 429 SER D C   1 
ATOM   4454 O  O   . SER B 2 429 ? 96.908  115.750 102.170 1.00 47.97  ? 429 SER D O   1 
ATOM   4455 C  CB  . SER B 2 429 ? 95.040  114.222 99.958  1.00 47.97  ? 429 SER D CB  1 
ATOM   4456 O  OG  . SER B 2 429 ? 94.721  114.102 98.583  1.00 47.97  ? 429 SER D OG  1 
ATOM   4457 N  N   . SER B 2 430 ? 97.070  113.508 102.306 1.00 45.21  ? 430 SER D N   1 
ATOM   4458 C  CA  . SER B 2 430 ? 97.445  113.562 103.716 1.00 45.21  ? 430 SER D CA  1 
ATOM   4459 C  C   . SER B 2 430 ? 98.776  114.282 103.900 1.00 45.21  ? 430 SER D C   1 
ATOM   4460 O  O   . SER B 2 430 ? 98.920  115.128 104.795 1.00 45.21  ? 430 SER D O   1 
ATOM   4461 C  CB  . SER B 2 430 ? 97.510  112.150 104.297 1.00 45.21  ? 430 SER D CB  1 
ATOM   4462 O  OG  . SER B 2 430 ? 96.237  111.530 104.268 1.00 45.21  ? 430 SER D OG  1 
ATOM   4463 N  N   . ALA B 2 431 ? 99.760  113.967 103.054 1.00 36.55  ? 431 ALA D N   1 
ATOM   4464 C  CA  . ALA B 2 431 ? 101.063 114.615 103.158 1.00 36.55  ? 431 ALA D CA  1 
ATOM   4465 C  C   . ALA B 2 431 ? 100.953 116.113 102.909 1.00 36.55  ? 431 ALA D C   1 
ATOM   4466 O  O   . ALA B 2 431 ? 101.545 116.920 103.636 1.00 36.55  ? 431 ALA D O   1 
ATOM   4467 C  CB  . ALA B 2 431 ? 102.046 113.978 102.176 1.00 36.55  ? 431 ALA D CB  1 
ATOM   4468 N  N   . LEU B 2 432 ? 100.195 116.504 101.882 1.00 40.76  ? 432 LEU D N   1 
ATOM   4469 C  CA  . LEU B 2 432 ? 100.035 117.923 101.581 1.00 40.76  ? 432 LEU D CA  1 
ATOM   4470 C  C   . LEU B 2 432 ? 99.315  118.651 102.708 1.00 40.76  ? 432 LEU D C   1 
ATOM   4471 O  O   . LEU B 2 432 ? 99.689  119.774 103.066 1.00 40.76  ? 432 LEU D O   1 
ATOM   4472 C  CB  . LEU B 2 432 ? 99.287  118.099 100.261 1.00 40.76  ? 432 LEU D CB  1 
ATOM   4473 C  CG  . LEU B 2 432 ? 100.143 118.438 99.040  1.00 40.76  ? 432 LEU D CG  1 
ATOM   4474 C  CD1 . LEU B 2 432 ? 100.586 119.888 99.092  1.00 40.76  ? 432 LEU D CD1 1 
ATOM   4475 C  CD2 . LEU B 2 432 ? 101.347 117.514 98.947  1.00 40.76  ? 432 LEU D CD2 1 
ATOM   4476 N  N   . LYS B 2 433 ? 98.281  118.030 103.281 1.00 45.75  ? 433 LYS D N   1 
ATOM   4477 C  CA  . LYS B 2 433 ? 97.560  118.653 104.385 1.00 45.75  ? 433 LYS D CA  1 
ATOM   4478 C  C   . LYS B 2 433 ? 98.469  118.849 105.590 1.00 45.75  ? 433 LYS D C   1 
ATOM   4479 O  O   . LYS B 2 433 ? 98.469  119.916 106.213 1.00 45.75  ? 433 LYS D O   1 
ATOM   4480 C  CB  . LYS B 2 433 ? 96.344  117.805 104.758 1.00 45.75  ? 433 LYS D CB  1 
ATOM   4481 C  CG  . LYS B 2 433 ? 95.450  118.431 105.812 1.00 45.75  ? 433 LYS D CG  1 
ATOM   4482 C  CD  . LYS B 2 433 ? 94.231  117.566 106.079 1.00 45.75  ? 433 LYS D CD  1 
ATOM   4483 C  CE  . LYS B 2 433 ? 93.306  118.212 107.095 1.00 45.75  ? 433 LYS D CE  1 
ATOM   4484 N  NZ  . LYS B 2 433 ? 92.102  117.377 107.357 1.00 45.75  ? 433 LYS D NZ  1 
ATOM   4485 N  N   . GLU B 2 434 ? 99.262  117.829 105.928 1.00 46.36  ? 434 GLU D N   1 
ATOM   4486 C  CA  . GLU B 2 434 ? 100.177 117.959 107.058 1.00 46.36  ? 434 GLU D CA  1 
ATOM   4487 C  C   . GLU B 2 434 ? 101.222 119.040 106.803 1.00 46.36  ? 434 GLU D C   1 
ATOM   4488 O  O   . GLU B 2 434 ? 101.523 119.845 107.694 1.00 46.36  ? 434 GLU D O   1 
ATOM   4489 C  CB  . GLU B 2 434 ? 100.847 116.617 107.346 1.00 46.36  ? 434 GLU D CB  1 
ATOM   4490 C  CG  . GLU B 2 434 ? 101.508 116.531 108.710 1.00 46.36  ? 434 GLU D CG  1 
ATOM   4491 C  CD  . GLU B 2 434 ? 101.846 115.106 109.101 1.00 46.36  ? 434 GLU D CD  1 
ATOM   4492 O  OE1 . GLU B 2 434 ? 101.378 114.175 108.413 1.00 46.36  ? 434 GLU D OE1 1 
ATOM   4493 O  OE2 . GLU B 2 434 ? 102.580 114.916 110.093 1.00 46.36  ? 434 GLU D OE2 1 
ATOM   4494 N  N   . LEU B 2 435 ? 101.778 119.080 105.588 1.00 42.53  ? 435 LEU D N   1 
ATOM   4495 C  CA  . LEU B 2 435 ? 102.789 120.083 105.269 1.00 42.53  ? 435 LEU D CA  1 
ATOM   4496 C  C   . LEU B 2 435 ? 102.214 121.491 105.333 1.00 42.53  ? 435 LEU D C   1 
ATOM   4497 O  O   . LEU B 2 435 ? 102.867 122.413 105.836 1.00 42.53  ? 435 LEU D O   1 
ATOM   4498 C  CB  . LEU B 2 435 ? 103.382 119.810 103.888 1.00 42.53  ? 435 LEU D CB  1 
ATOM   4499 C  CG  . LEU B 2 435 ? 104.469 120.780 103.428 1.00 42.53  ? 435 LEU D CG  1 
ATOM   4500 C  CD1 . LEU B 2 435 ? 105.614 120.806 104.424 1.00 42.53  ? 435 LEU D CD1 1 
ATOM   4501 C  CD2 . LEU B 2 435 ? 104.969 120.404 102.046 1.00 42.53  ? 435 LEU D CD2 1 
ATOM   4502 N  N   . ALA B 2 436 ? 100.995 121.681 104.827 1.00 50.65  ? 436 ALA D N   1 
ATOM   4503 C  CA  . ALA B 2 436 ? 100.392 123.009 104.856 1.00 50.65  ? 436 ALA D CA  1 
ATOM   4504 C  C   . ALA B 2 436 ? 100.000 123.408 106.273 1.00 50.65  ? 436 ALA D C   1 
ATOM   4505 O  O   . ALA B 2 436 ? 100.052 124.592 106.628 1.00 50.65  ? 436 ALA D O   1 
ATOM   4506 C  CB  . ALA B 2 436 ? 99.184  123.056 103.921 1.00 50.65  ? 436 ALA D CB  1 
ATOM   4507 N  N   . VAL B 2 437 ? 99.598  122.438 107.099 1.00 53.99  ? 437 VAL D N   1 
ATOM   4508 C  CA  . VAL B 2 437 ? 99.294  122.736 108.496 1.00 53.99  ? 437 VAL D CA  1 
ATOM   4509 C  C   . VAL B 2 437 ? 100.552 123.179 109.230 1.00 53.99  ? 437 VAL D C   1 
ATOM   4510 O  O   . VAL B 2 437 ? 100.533 124.152 109.994 1.00 53.99  ? 437 VAL D O   1 
ATOM   4511 C  CB  . VAL B 2 437 ? 98.638  121.517 109.172 1.00 53.99  ? 437 VAL D CB  1 
ATOM   4512 C  CG1 . VAL B 2 437 ? 98.932  121.504 110.665 1.00 53.99  ? 437 VAL D CG1 1 
ATOM   4513 C  CG2 . VAL B 2 437 ? 97.140  121.519 108.923 1.00 53.99  ? 437 VAL D CG2 1 
ATOM   4514 N  N   . ARG B 2 438 ? 101.666 122.476 109.010 1.00 52.40  ? 438 ARG D N   1 
ATOM   4515 C  CA  . ARG B 2 438 ? 102.922 122.867 109.645 1.00 52.40  ? 438 ARG D CA  1 
ATOM   4516 C  C   . ARG B 2 438 ? 103.388 124.231 109.146 1.00 52.40  ? 438 ARG D C   1 
ATOM   4517 O  O   . ARG B 2 438 ? 103.917 125.041 109.915 1.00 52.40  ? 438 ARG D O   1 
ATOM   4518 C  CB  . ARG B 2 438 ? 103.990 121.802 109.392 1.00 52.40  ? 438 ARG D CB  1 
ATOM   4519 C  CG  . ARG B 2 438 ? 105.419 122.291 109.561 1.00 52.40  ? 438 ARG D CG  1 
ATOM   4520 C  CD  . ARG B 2 438 ? 105.759 122.519 111.024 1.00 52.40  ? 438 ARG D CD  1 
ATOM   4521 N  NE  . ARG B 2 438 ? 107.089 123.094 111.186 1.00 52.40  ? 438 ARG D NE  1 
ATOM   4522 C  CZ  . ARG B 2 438 ? 107.992 122.661 112.054 1.00 52.40  ? 438 ARG D CZ  1 
ATOM   4523 N  NH1 . ARG B 2 438 ? 107.743 121.642 112.860 1.00 52.40  ? 438 ARG D NH1 1 
ATOM   4524 N  NH2 . ARG B 2 438 ? 109.176 123.264 112.114 1.00 52.40  ? 438 ARG D NH2 1 
ATOM   4525 N  N   . MET B 2 439 ? 103.187 124.505 107.855 1.00 61.93  ? 439 MET D N   1 
ATOM   4526 C  CA  . MET B 2 439 ? 103.654 125.761 107.278 1.00 61.93  ? 439 MET D CA  1 
ATOM   4527 C  C   . MET B 2 439 ? 102.767 126.936 107.671 1.00 61.93  ? 439 MET D C   1 
ATOM   4528 O  O   . MET B 2 439 ? 103.123 128.091 107.412 1.00 61.93  ? 439 MET D O   1 
ATOM   4529 C  CB  . MET B 2 439 ? 103.722 125.637 105.756 1.00 61.93  ? 439 MET D CB  1 
ATOM   4530 C  CG  . MET B 2 439 ? 104.810 126.469 105.106 1.00 61.93  ? 439 MET D CG  1 
ATOM   4531 S  SD  . MET B 2 439 ? 105.321 125.793 103.516 1.00 61.93  ? 439 MET D SD  1 
ATOM   4532 C  CE  . MET B 2 439 ? 103.761 125.787 102.638 1.00 61.93  ? 439 MET D CE  1 
ATOM   4533 N  N   . ARG B 2 440 ? 101.619 126.666 108.296 1.00 86.74  ? 440 ARG D N   1 
ATOM   4534 C  CA  . ARG B 2 440 ? 100.672 127.728 108.621 1.00 86.74  ? 440 ARG D CA  1 
ATOM   4535 C  C   . ARG B 2 440 ? 101.264 128.700 109.639 1.00 86.74  ? 440 ARG D C   1 
ATOM   4536 O  O   . ARG B 2 440 ? 100.925 129.889 109.649 1.00 86.74  ? 440 ARG D O   1 
ATOM   4537 C  CB  . ARG B 2 440 ? 99.375  127.106 109.150 1.00 86.74  ? 440 ARG D CB  1 
ATOM   4538 C  CG  . ARG B 2 440 ? 98.214  128.062 109.427 1.00 86.74  ? 440 ARG D CG  1 
ATOM   4539 C  CD  . ARG B 2 440 ? 98.193  129.268 108.490 1.00 86.74  ? 440 ARG D CD  1 
ATOM   4540 N  NE  . ARG B 2 440 ? 97.249  130.309 108.890 1.00 86.74  ? 440 ARG D NE  1 
ATOM   4541 C  CZ  . ARG B 2 440 ? 97.199  130.894 110.081 1.00 86.74  ? 440 ARG D CZ  1 
ATOM   4542 N  NH1 . ARG B 2 440 ? 98.088  130.631 111.026 1.00 86.74  ? 440 ARG D NH1 1 
ATOM   4543 N  NH2 . ARG B 2 440 ? 96.243  131.786 110.324 1.00 86.74  ? 440 ARG D NH2 1 
ATOM   4544 N  N   . ASP B 2 441 ? 102.166 128.213 110.496 1.00 90.92  ? 441 ASP D N   1 
ATOM   4545 C  CA  . ASP B 2 441 ? 102.690 129.039 111.580 1.00 90.92  ? 441 ASP D CA  1 
ATOM   4546 C  C   . ASP B 2 441 ? 103.458 130.250 111.064 1.00 90.92  ? 441 ASP D C   1 
ATOM   4547 O  O   . ASP B 2 441 ? 103.327 131.347 111.618 1.00 90.92  ? 441 ASP D O   1 
ATOM   4548 C  CB  . ASP B 2 441 ? 103.584 128.200 112.492 1.00 90.92  ? 441 ASP D CB  1 
ATOM   4549 C  CG  . ASP B 2 441 ? 102.791 127.337 113.452 1.00 90.92  ? 441 ASP D CG  1 
ATOM   4550 O  OD1 . ASP B 2 441 ? 101.572 127.570 113.596 1.00 90.92  ? 441 ASP D OD1 1 
ATOM   4551 O  OD2 . ASP B 2 441 ? 103.386 126.424 114.063 1.00 90.92  ? 441 ASP D OD2 1 
ATOM   4552 N  N   . HIS B 2 442 ? 104.257 130.079 110.015 1.00 88.13  ? 442 HIS D N   1 
ATOM   4553 C  CA  . HIS B 2 442 ? 105.132 131.138 109.531 1.00 88.13  ? 442 HIS D CA  1 
ATOM   4554 C  C   . HIS B 2 442 ? 104.502 131.987 108.436 1.00 88.13  ? 442 HIS D C   1 
ATOM   4555 O  O   . HIS B 2 442 ? 105.234 132.510 107.590 1.00 88.13  ? 442 HIS D O   1 
ATOM   4556 C  CB  . HIS B 2 442 ? 106.443 130.541 109.010 1.00 88.13  ? 442 HIS D CB  1 
ATOM   4557 C  CG  . HIS B 2 442 ? 107.121 129.624 109.979 1.00 88.13  ? 442 HIS D CG  1 
ATOM   4558 N  ND1 . HIS B 2 442 ? 107.647 130.061 111.175 1.00 88.13  ? 442 HIS D ND1 1 
ATOM   4559 C  CD2 . HIS B 2 442 ? 107.363 128.293 109.925 1.00 88.13  ? 442 HIS D CD2 1 
ATOM   4560 C  CE1 . HIS B 2 442 ? 108.182 129.038 111.817 1.00 88.13  ? 442 HIS D CE1 1 
ATOM   4561 N  NE2 . HIS B 2 442 ? 108.023 127.953 111.080 1.00 88.13  ? 442 HIS D NE2 1 
ATOM   4562 N  N   . ARG B 2 443 ? 103.176 132.141 108.427 1.00 100.00 ? 443 ARG D N   1 
ATOM   4563 C  CA  . ARG B 2 443 ? 102.512 132.813 107.314 1.00 100.00 ? 443 ARG D CA  1 
ATOM   4564 C  C   . ARG B 2 443 ? 102.967 134.263 107.177 1.00 100.00 ? 443 ARG D C   1 
ATOM   4565 O  O   . ARG B 2 443 ? 103.252 134.734 106.071 1.00 100.00 ? 443 ARG D O   1 
ATOM   4566 C  CB  . ARG B 2 443 ? 100.993 132.737 107.491 1.00 100.00 ? 443 ARG D CB  1 
ATOM   4567 C  CG  . ARG B 2 443 ? 100.195 133.289 106.316 1.00 100.00 ? 443 ARG D CG  1 
ATOM   4568 C  CD  . ARG B 2 443 ? 99.680  134.693 106.588 1.00 100.00 ? 443 ARG D CD  1 
ATOM   4569 N  NE  . ARG B 2 443 ? 98.709  135.122 105.589 1.00 100.00 ? 443 ARG D NE  1 
ATOM   4570 C  CZ  . ARG B 2 443 ? 98.017  136.251 105.652 1.00 100.00 ? 443 ARG D CZ  1 
ATOM   4571 N  NH1 . ARG B 2 443 ? 98.165  137.097 106.658 1.00 100.00 ? 443 ARG D NH1 1 
ATOM   4572 N  NH2 . ARG B 2 443 ? 97.156  136.540 104.680 1.00 100.00 ? 443 ARG D NH2 1 
ATOM   4573 N  N   . ASP B 2 444 ? 103.046 134.987 108.297 1.00 101.74 ? 444 ASP D N   1 
ATOM   4574 C  CA  . ASP B 2 444 ? 103.395 136.404 108.234 1.00 101.74 ? 444 ASP D CA  1 
ATOM   4575 C  C   . ASP B 2 444 ? 104.828 136.608 107.756 1.00 101.74 ? 444 ASP D C   1 
ATOM   4576 O  O   . ASP B 2 444 ? 105.078 137.416 106.852 1.00 101.74 ? 444 ASP D O   1 
ATOM   4577 C  CB  . ASP B 2 444 ? 103.192 137.055 109.602 1.00 101.74 ? 444 ASP D CB  1 
ATOM   4578 C  CG  . ASP B 2 444 ? 101.851 136.712 110.216 1.00 101.74 ? 444 ASP D CG  1 
ATOM   4579 O  OD1 . ASP B 2 444 ? 100.850 137.376 109.873 1.00 101.74 ? 444 ASP D OD1 1 
ATOM   4580 O  OD2 . ASP B 2 444 ? 101.796 135.777 111.042 1.00 101.74 ? 444 ASP D OD2 1 
ATOM   4581 N  N   . GLU B 2 445 ? 105.780 135.886 108.351 1.00 103.56 ? 445 GLU D N   1 
ATOM   4582 C  CA  . GLU B 2 445 ? 107.174 136.023 107.942 1.00 103.56 ? 445 GLU D CA  1 
ATOM   4583 C  C   . GLU B 2 445 ? 107.374 135.555 106.506 1.00 103.56 ? 445 GLU D C   1 
ATOM   4584 O  O   . GLU B 2 445 ? 108.146 136.158 105.753 1.00 103.56 ? 445 GLU D O   1 
ATOM   4585 C  CB  . GLU B 2 445 ? 108.079 135.246 108.899 1.00 103.56 ? 445 GLU D CB  1 
ATOM   4586 C  CG  . GLU B 2 445 ? 109.528 135.152 108.450 1.00 103.56 ? 445 GLU D CG  1 
ATOM   4587 C  CD  . GLU B 2 445 ? 110.454 134.696 109.561 1.00 103.56 ? 445 GLU D CD  1 
ATOM   4588 O  OE1 . GLU B 2 445 ? 109.959 134.103 110.543 1.00 103.56 ? 445 GLU D OE1 1 
ATOM   4589 O  OE2 . GLU B 2 445 ? 111.676 134.930 109.452 1.00 103.56 ? 445 GLU D OE2 1 
ATOM   4590 N  N   . LEU B 2 446 ? 106.688 134.480 106.111 1.00 91.07  ? 446 LEU D N   1 
ATOM   4591 C  CA  . LEU B 2 446 ? 106.786 134.001 104.737 1.00 91.07  ? 446 LEU D CA  1 
ATOM   4592 C  C   . LEU B 2 446 ? 106.268 135.042 103.752 1.00 91.07  ? 446 LEU D C   1 
ATOM   4593 O  O   . LEU B 2 446 ? 106.894 135.292 102.713 1.00 91.07  ? 446 LEU D O   1 
ATOM   4594 C  CB  . LEU B 2 446 ? 106.017 132.689 104.592 1.00 91.07  ? 446 LEU D CB  1 
ATOM   4595 C  CG  . LEU B 2 446 ? 106.265 131.822 103.361 1.00 91.07  ? 446 LEU D CG  1 
ATOM   4596 C  CD1 . LEU B 2 446 ? 106.425 130.371 103.775 1.00 91.07  ? 446 LEU D CD1 1 
ATOM   4597 C  CD2 . LEU B 2 446 ? 105.115 131.972 102.388 1.00 91.07  ? 446 LEU D CD2 1 
ATOM   4598 N  N   . GLU B 2 447 ? 105.129 135.665 104.063 1.00 94.02  ? 447 GLU D N   1 
ATOM   4599 C  CA  . GLU B 2 447 ? 104.591 136.705 103.192 1.00 94.02  ? 447 GLU D CA  1 
ATOM   4600 C  C   . GLU B 2 447 ? 105.535 137.898 103.119 1.00 94.02  ? 447 GLU D C   1 
ATOM   4601 O  O   . GLU B 2 447 ? 105.749 138.471 102.045 1.00 94.02  ? 447 GLU D O   1 
ATOM   4602 C  CB  . GLU B 2 447 ? 103.208 137.137 103.683 1.00 94.02  ? 447 GLU D CB  1 
ATOM   4603 C  CG  . GLU B 2 447 ? 102.785 138.517 103.208 1.00 94.02  ? 447 GLU D CG  1 
ATOM   4604 C  CD  . GLU B 2 447 ? 101.359 138.546 102.696 1.00 94.02  ? 447 GLU D CD  1 
ATOM   4605 O  OE1 . GLU B 2 447 ? 100.708 137.481 102.689 1.00 94.02  ? 447 GLU D OE1 1 
ATOM   4606 O  OE2 . GLU B 2 447 ? 100.891 139.633 102.300 1.00 94.02  ? 447 GLU D OE2 1 
ATOM   4607 N  N   . ASP B 2 448 ? 106.112 138.286 104.259 1.00 96.63  ? 448 ASP D N   1 
ATOM   4608 C  CA  . ASP B 2 448 ? 107.054 139.402 104.264 1.00 96.63  ? 448 ASP D CA  1 
ATOM   4609 C  C   . ASP B 2 448 ? 108.284 139.089 103.421 1.00 96.63  ? 448 ASP D C   1 
ATOM   4610 O  O   . ASP B 2 448 ? 108.779 139.952 102.687 1.00 96.63  ? 448 ASP D O   1 
ATOM   4611 C  CB  . ASP B 2 448 ? 107.456 139.743 105.698 1.00 96.63  ? 448 ASP D CB  1 
ATOM   4612 C  CG  . ASP B 2 448 ? 107.513 141.237 105.945 1.00 96.63  ? 448 ASP D CG  1 
ATOM   4613 O  OD1 . ASP B 2 448 ? 106.764 141.979 105.276 1.00 96.63  ? 448 ASP D OD1 1 
ATOM   4614 O  OD2 . ASP B 2 448 ? 108.305 141.668 106.809 1.00 96.63  ? 448 ASP D OD2 1 
ATOM   4615 N  N   . GLU B 2 449 ? 108.794 137.859 103.516 1.00 89.69  ? 449 GLU D N   1 
ATOM   4616 C  CA  . GLU B 2 449 ? 109.938 137.464 102.701 1.00 89.69  ? 449 GLU D CA  1 
ATOM   4617 C  C   . GLU B 2 449 ? 109.585 137.464 101.220 1.00 89.69  ? 449 GLU D C   1 
ATOM   4618 O  O   . GLU B 2 449 ? 110.401 137.868 100.383 1.00 89.69  ? 449 GLU D O   1 
ATOM   4619 C  CB  . GLU B 2 449 ? 110.444 136.089 103.136 1.00 89.69  ? 449 GLU D CB  1 
ATOM   4620 C  CG  . GLU B 2 449 ? 111.140 136.079 104.488 1.00 89.69  ? 449 GLU D CG  1 
ATOM   4621 C  CD  . GLU B 2 449 ? 112.596 136.494 104.398 1.00 89.69  ? 449 GLU D CD  1 
ATOM   4622 O  OE1 . GLU B 2 449 ? 113.365 135.820 103.681 1.00 89.69  ? 449 GLU D OE1 1 
ATOM   4623 O  OE2 . GLU B 2 449 ? 112.972 137.492 105.047 1.00 89.69  ? 449 GLU D OE2 1 
ATOM   4624 N  N   . PHE B 2 450 ? 108.380 137.004 100.875 1.00 84.91  ? 450 PHE D N   1 
ATOM   4625 C  CA  . PHE B 2 450 ? 107.945 137.056 99.483  1.00 84.91  ? 450 PHE D CA  1 
ATOM   4626 C  C   . PHE B 2 450 ? 107.833 138.495 98.994  1.00 84.91  ? 450 PHE D C   1 
ATOM   4627 O  O   . PHE B 2 450 ? 108.209 138.804 97.857  1.00 84.91  ? 450 PHE D O   1 
ATOM   4628 C  CB  . PHE B 2 450 ? 106.611 136.330 99.316  1.00 84.91  ? 450 PHE D CB  1 
ATOM   4629 C  CG  . PHE B 2 450 ? 106.753 134.880 98.956  1.00 84.91  ? 450 PHE D CG  1 
ATOM   4630 C  CD1 . PHE B 2 450 ? 107.791 134.454 98.147  1.00 84.91  ? 450 PHE D CD1 1 
ATOM   4631 C  CD2 . PHE B 2 450 ? 105.845 133.944 99.419  1.00 84.91  ? 450 PHE D CD2 1 
ATOM   4632 C  CE1 . PHE B 2 450 ? 107.924 133.123 97.812  1.00 84.91  ? 450 PHE D CE1 1 
ATOM   4633 C  CE2 . PHE B 2 450 ? 105.974 132.613 99.085  1.00 84.91  ? 450 PHE D CE2 1 
ATOM   4634 C  CZ  . PHE B 2 450 ? 107.015 132.202 98.282  1.00 84.91  ? 450 PHE D CZ  1 
ATOM   4635 N  N   . ARG B 2 451 ? 107.314 139.388 99.840  1.00 90.14  ? 451 ARG D N   1 
ATOM   4636 C  CA  . ARG B 2 451 ? 107.187 140.790 99.454  1.00 90.14  ? 451 ARG D CA  1 
ATOM   4637 C  C   . ARG B 2 451 ? 108.553 141.429 99.236  1.00 90.14  ? 451 ARG D C   1 
ATOM   4638 O  O   . ARG B 2 451 ? 108.730 142.237 98.316  1.00 90.14  ? 451 ARG D O   1 
ATOM   4639 C  CB  . ARG B 2 451 ? 106.401 141.556 100.517 1.00 90.14  ? 451 ARG D CB  1 
ATOM   4640 C  CG  . ARG B 2 451 ? 105.833 142.879 100.037 1.00 90.14  ? 451 ARG D CG  1 
ATOM   4641 C  CD  . ARG B 2 451 ? 104.836 142.674 98.907  1.00 90.14  ? 451 ARG D CD  1 
ATOM   4642 N  NE  . ARG B 2 451 ? 103.911 141.579 99.176  1.00 90.14  ? 451 ARG D NE  1 
ATOM   4643 C  CZ  . ARG B 2 451 ? 102.922 141.628 100.059 1.00 90.14  ? 451 ARG D CZ  1 
ATOM   4644 N  NH1 . ARG B 2 451 ? 102.687 142.715 100.776 1.00 90.14  ? 451 ARG D NH1 1 
ATOM   4645 N  NH2 . ARG B 2 451 ? 102.147 140.560 100.223 1.00 90.14  ? 451 ARG D NH2 1 
ATOM   4646 N  N   . LYS B 2 452 ? 109.530 141.083 100.078 1.00 89.06  ? 452 LYS D N   1 
ATOM   4647 C  CA  . LYS B 2 452 ? 110.862 141.668 99.953  1.00 89.06  ? 452 LYS D CA  1 
ATOM   4648 C  C   . LYS B 2 452 ? 111.514 141.288 98.630  1.00 89.06  ? 452 LYS D C   1 
ATOM   4649 O  O   . LYS B 2 452 ? 112.199 142.109 98.009  1.00 89.06  ? 452 LYS D O   1 
ATOM   4650 C  CB  . LYS B 2 452 ? 111.738 141.230 101.127 1.00 89.06  ? 452 LYS D CB  1 
ATOM   4651 C  CG  . LYS B 2 452 ? 112.882 142.181 101.435 1.00 89.06  ? 452 LYS D CG  1 
ATOM   4652 C  CD  . LYS B 2 452 ? 113.428 141.954 102.836 1.00 89.06  ? 452 LYS D CD  1 
ATOM   4653 C  CE  . LYS B 2 452 ? 114.393 140.780 102.869 1.00 89.06  ? 452 LYS D CE  1 
ATOM   4654 N  NZ  . LYS B 2 452 ? 114.512 140.198 104.234 1.00 89.06  ? 452 LYS D NZ  1 
ATOM   4655 N  N   . TYR B 2 453 ? 111.314 140.048 98.181  1.00 87.40  ? 453 TYR D N   1 
ATOM   4656 C  CA  . TYR B 2 453 ? 111.948 139.582 96.955  1.00 87.40  ? 453 TYR D CA  1 
ATOM   4657 C  C   . TYR B 2 453 ? 111.263 140.100 95.698  1.00 87.40  ? 453 TYR D C   1 
ATOM   4658 O  O   . TYR B 2 453 ? 111.730 139.802 94.594  1.00 87.40  ? 453 TYR D O   1 
ATOM   4659 C  CB  . TYR B 2 453 ? 111.986 138.054 96.933  1.00 87.40  ? 453 TYR D CB  1 
ATOM   4660 C  CG  . TYR B 2 453 ? 113.373 137.489 97.126  1.00 87.40  ? 453 TYR D CG  1 
ATOM   4661 C  CD1 . TYR B 2 453 ? 114.337 137.610 96.135  1.00 87.40  ? 453 TYR D CD1 1 
ATOM   4662 C  CD2 . TYR B 2 453 ? 113.722 136.843 98.303  1.00 87.40  ? 453 TYR D CD2 1 
ATOM   4663 C  CE1 . TYR B 2 453 ? 115.608 137.098 96.310  1.00 87.40  ? 453 TYR D CE1 1 
ATOM   4664 C  CE2 . TYR B 2 453 ? 114.989 136.327 98.487  1.00 87.40  ? 453 TYR D CE2 1 
ATOM   4665 C  CZ  . TYR B 2 453 ? 115.928 136.457 97.487  1.00 87.40  ? 453 TYR D CZ  1 
ATOM   4666 O  OH  . TYR B 2 453 ? 117.192 135.945 97.665  1.00 87.40  ? 453 TYR D OH  1 
ATOM   4667 N  N   . ASP B 2 454 ? 110.172 140.851 95.834  1.00 92.38  ? 454 ASP D N   1 
ATOM   4668 C  CA  . ASP B 2 454 ? 109.510 141.470 94.694  1.00 92.38  ? 454 ASP D CA  1 
ATOM   4669 C  C   . ASP B 2 454 ? 109.682 142.981 94.798  1.00 92.38  ? 454 ASP D C   1 
ATOM   4670 O  O   . ASP B 2 454 ? 108.775 143.679 95.268  1.00 92.38  ? 454 ASP D O   1 
ATOM   4671 C  CB  . ASP B 2 454 ? 108.029 141.085 94.655  1.00 92.38  ? 454 ASP D CB  1 
ATOM   4672 C  CG  . ASP B 2 454 ? 107.321 141.577 93.401  1.00 92.38  ? 454 ASP D CG  1 
ATOM   4673 O  OD1 . ASP B 2 454 ? 106.147 141.201 93.202  1.00 92.38  ? 454 ASP D OD1 1 
ATOM   4674 O  OD2 . ASP B 2 454 ? 107.932 142.324 92.608  1.00 92.38  ? 454 ASP D OD2 1 
ATOM   4675 N  N   . PRO B 2 455 ? 110.831 143.521 94.376  1.00 93.02  ? 455 PRO D N   1 
ATOM   4676 C  CA  . PRO B 2 455 ? 111.076 144.963 94.540  1.00 93.02  ? 455 PRO D CA  1 
ATOM   4677 C  C   . PRO B 2 455 ? 110.137 145.849 93.740  1.00 93.02  ? 455 PRO D C   1 
ATOM   4678 O  O   . PRO B 2 455 ? 109.979 147.024 94.096  1.00 93.02  ? 455 PRO D O   1 
ATOM   4679 C  CB  . PRO B 2 455 ? 112.525 145.125 94.064  1.00 93.02  ? 455 PRO D CB  1 
ATOM   4680 C  CG  . PRO B 2 455 ? 112.725 143.998 93.108  1.00 93.02  ? 455 PRO D CG  1 
ATOM   4681 C  CD  . PRO B 2 455 ? 111.933 142.850 93.666  1.00 93.02  ? 455 PRO D CD  1 
ATOM   4682 N  N   . LYS B 2 456 ? 109.513 145.337 92.679  1.00 93.05  ? 456 LYS D N   1 
ATOM   4683 C  CA  . LYS B 2 456 ? 108.622 146.128 91.841  1.00 93.05  ? 456 LYS D CA  1 
ATOM   4684 C  C   . LYS B 2 456 ? 107.158 145.747 92.031  1.00 93.05  ? 456 LYS D C   1 
ATOM   4685 O  O   . LYS B 2 456 ? 106.312 146.138 91.220  1.00 93.05  ? 456 LYS D O   1 
ATOM   4686 C  CB  . LYS B 2 456 ? 109.023 145.996 90.371  1.00 93.05  ? 456 LYS D CB  1 
ATOM   4687 C  CG  . LYS B 2 456 ? 110.493 146.285 90.109  1.00 93.05  ? 456 LYS D CG  1 
ATOM   4688 C  CD  . LYS B 2 456 ? 110.792 146.362 88.620  1.00 93.05  ? 456 LYS D CD  1 
ATOM   4689 C  CE  . LYS B 2 456 ? 110.213 147.627 88.008  1.00 93.05  ? 456 LYS D CE  1 
ATOM   4690 N  NZ  . LYS B 2 456 ? 110.612 147.789 86.582  1.00 93.05  ? 456 LYS D NZ  1 
ATOM   4691 N  N   . ASP B 2 457 ? 106.852 144.989 93.091  1.00 94.38  ? 457 ASP D N   1 
ATOM   4692 C  CA  . ASP B 2 457 ? 105.489 144.570 93.448  1.00 94.38  ? 457 ASP D CA  1 
ATOM   4693 C  C   . ASP B 2 457 ? 104.687 144.113 92.230  1.00 94.38  ? 457 ASP D C   1 
ATOM   4694 O  O   . ASP B 2 457 ? 103.493 144.392 92.102  1.00 94.38  ? 457 ASP D O   1 
ATOM   4695 C  CB  . ASP B 2 457 ? 104.747 145.672 94.217  1.00 94.38  ? 457 ASP D CB  1 
ATOM   4696 C  CG  . ASP B 2 457 ? 104.617 146.963 93.431  1.00 94.38  ? 457 ASP D CG  1 
ATOM   4697 O  OD1 . ASP B 2 457 ? 105.507 147.830 93.559  1.00 94.38  ? 457 ASP D OD1 1 
ATOM   4698 O  OD2 . ASP B 2 457 ? 103.623 147.116 92.689  1.00 94.38  ? 457 ASP D OD2 1 
ATOM   4699 N  N   . SER B 2 458 ? 105.353 143.391 91.326  1.00 96.87  ? 458 SER D N   1 
ATOM   4700 C  CA  . SER B 2 458 ? 104.671 142.893 90.136  1.00 96.87  ? 458 SER D CA  1 
ATOM   4701 C  C   . SER B 2 458 ? 103.758 141.717 90.460  1.00 96.87  ? 458 SER D C   1 
ATOM   4702 O  O   . SER B 2 458 ? 102.768 141.491 89.756  1.00 96.87  ? 458 SER D O   1 
ATOM   4703 C  CB  . SER B 2 458 ? 105.693 142.492 89.072  1.00 96.87  ? 458 SER D CB  1 
ATOM   4704 O  OG  . SER B 2 458 ? 106.431 141.352 89.477  1.00 96.87  ? 458 SER D OG  1 
ATOM   4705 N  N   . GLY B 2 459 ? 104.068 140.966 91.514  1.00 94.86  ? 459 GLY D N   1 
ATOM   4706 C  CA  . GLY B 2 459 ? 103.293 139.804 91.891  1.00 94.86  ? 459 GLY D CA  1 
ATOM   4707 C  C   . GLY B 2 459 ? 103.860 138.478 91.438  1.00 94.86  ? 459 GLY D C   1 
ATOM   4708 O  O   . GLY B 2 459 ? 103.254 137.437 91.721  1.00 94.86  ? 459 GLY D O   1 
ATOM   4709 N  N   . TYR B 2 460 ? 104.996 138.478 90.746  1.00 96.86  ? 460 TYR D N   1 
ATOM   4710 C  CA  . TYR B 2 460 ? 105.612 137.245 90.282  1.00 96.86  ? 460 TYR D CA  1 
ATOM   4711 C  C   . TYR B 2 460 ? 107.102 137.291 90.585  1.00 96.86  ? 460 TYR D C   1 
ATOM   4712 O  O   . TYR B 2 460 ? 107.766 138.311 90.382  1.00 96.86  ? 460 TYR D O   1 
ATOM   4713 C  CB  . TYR B 2 460 ? 105.376 137.027 88.782  1.00 96.86  ? 460 TYR D CB  1 
ATOM   4714 C  CG  . TYR B 2 460 ? 104.017 136.456 88.449  1.00 96.86  ? 460 TYR D CG  1 
ATOM   4715 C  CD1 . TYR B 2 460 ? 102.900 137.277 88.363  1.00 96.86  ? 460 TYR D CD1 1 
ATOM   4716 C  CD2 . TYR B 2 460 ? 103.851 135.098 88.216  1.00 96.86  ? 460 TYR D CD2 1 
ATOM   4717 C  CE1 . TYR B 2 460 ? 101.656 136.759 88.057  1.00 96.86  ? 460 TYR D CE1 1 
ATOM   4718 C  CE2 . TYR B 2 460 ? 102.613 134.572 87.906  1.00 96.86  ? 460 TYR D CE2 1 
ATOM   4719 C  CZ  . TYR B 2 460 ? 101.518 135.406 87.830  1.00 96.86  ? 460 TYR D CZ  1 
ATOM   4720 O  OH  . TYR B 2 460 ? 100.282 134.886 87.524  1.00 96.86  ? 460 TYR D OH  1 
ATOM   4721 N  N   . ILE B 2 461 ? 107.623 136.166 91.079  1.00 88.80  ? 461 ILE D N   1 
ATOM   4722 C  CA  . ILE B 2 461 ? 109.031 136.038 91.429  1.00 88.80  ? 461 ILE D CA  1 
ATOM   4723 C  C   . ILE B 2 461 ? 109.594 134.791 90.760  1.00 88.80  ? 461 ILE D C   1 
ATOM   4724 O  O   . ILE B 2 461 ? 108.859 133.894 90.343  1.00 88.80  ? 461 ILE D O   1 
ATOM   4725 C  CB  . ILE B 2 461 ? 109.259 135.984 92.958  1.00 88.80  ? 461 ILE D CB  1 
ATOM   4726 C  CG1 . ILE B 2 461 ? 109.167 134.549 93.474  1.00 88.80  ? 461 ILE D CG1 1 
ATOM   4727 C  CG2 . ILE B 2 461 ? 108.266 136.875 93.688  1.00 88.80  ? 461 ILE D CG2 1 
ATOM   4728 C  CD1 . ILE B 2 461 ? 109.760 134.371 94.848  1.00 88.80  ? 461 ILE D CD1 1 
ATOM   4729 N  N   . SER B 2 462 ? 110.920 134.750 90.655  1.00 81.32  ? 462 SER D N   1 
ATOM   4730 C  CA  . SER B 2 462 ? 111.588 133.663 89.957  1.00 81.32  ? 462 SER D CA  1 
ATOM   4731 C  C   . SER B 2 462 ? 111.507 132.365 90.759  1.00 81.32  ? 462 SER D C   1 
ATOM   4732 O  O   . SER B 2 462 ? 111.244 132.358 91.965  1.00 81.32  ? 462 SER D O   1 
ATOM   4733 C  CB  . SER B 2 462 ? 113.049 134.018 89.683  1.00 81.32  ? 462 SER D CB  1 
ATOM   4734 O  OG  . SER B 2 462 ? 113.849 133.802 90.831  1.00 81.32  ? 462 SER D OG  1 
ATOM   4735 N  N   . ILE B 2 463 ? 111.736 131.251 90.058  1.00 77.93  ? 463 ILE D N   1 
ATOM   4736 C  CA  . ILE B 2 463 ? 111.679 129.935 90.692  1.00 77.93  ? 463 ILE D CA  1 
ATOM   4737 C  C   . ILE B 2 463 ? 112.766 129.808 91.752  1.00 77.93  ? 463 ILE D C   1 
ATOM   4738 O  O   . ILE B 2 463 ? 112.532 129.288 92.851  1.00 77.93  ? 463 ILE D O   1 
ATOM   4739 C  CB  . ILE B 2 463 ? 111.797 128.823 89.635  1.00 77.93  ? 463 ILE D CB  1 
ATOM   4740 C  CG1 . ILE B 2 463 ? 110.880 129.110 88.445  1.00 77.93  ? 463 ILE D CG1 1 
ATOM   4741 C  CG2 . ILE B 2 463 ? 111.471 127.471 90.248  1.00 77.93  ? 463 ILE D CG2 1 
ATOM   4742 C  CD1 . ILE B 2 463 ? 109.432 129.312 88.820  1.00 77.93  ? 463 ILE D CD1 1 
ATOM   4743 N  N   . SER B 2 464 ? 113.978 130.268 91.430  1.00 70.56  ? 464 SER D N   1 
ATOM   4744 C  CA  . SER B 2 464 ? 115.078 130.182 92.384  1.00 70.56  ? 464 SER D CA  1 
ATOM   4745 C  C   . SER B 2 464 ? 114.785 130.998 93.635  1.00 70.56  ? 464 SER D C   1 
ATOM   4746 O  O   . SER B 2 464 ? 115.057 130.550 94.755  1.00 70.56  ? 464 SER D O   1 
ATOM   4747 C  CB  . SER B 2 464 ? 116.378 130.650 91.730  1.00 70.56  ? 464 SER D CB  1 
ATOM   4748 O  OG  . SER B 2 464 ? 116.704 129.842 90.613  1.00 70.56  ? 464 SER D OG  1 
ATOM   4749 N  N   . HIS B 2 465 ? 114.225 132.197 93.465  1.00 79.88  ? 465 HIS D N   1 
ATOM   4750 C  CA  . HIS B 2 465 ? 113.862 133.014 94.618  1.00 79.88  ? 465 HIS D CA  1 
ATOM   4751 C  C   . HIS B 2 465 ? 112.787 132.331 95.454  1.00 79.88  ? 465 HIS D C   1 
ATOM   4752 O  O   . HIS B 2 465 ? 112.827 132.368 96.688  1.00 79.88  ? 465 HIS D O   1 
ATOM   4753 C  CB  . HIS B 2 465 ? 113.394 134.395 94.156  1.00 79.88  ? 465 HIS D CB  1 
ATOM   4754 C  CG  . HIS B 2 465 ? 114.453 135.190 93.458  1.00 79.88  ? 465 HIS D CG  1 
ATOM   4755 N  ND1 . HIS B 2 465 ? 114.169 136.074 92.440  1.00 79.88  ? 465 HIS D ND1 1 
ATOM   4756 C  CD2 . HIS B 2 465 ? 115.796 135.227 93.624  1.00 79.88  ? 465 HIS D CD2 1 
ATOM   4757 C  CE1 . HIS B 2 465 ? 115.290 136.627 92.014  1.00 79.88  ? 465 HIS D CE1 1 
ATOM   4758 N  NE2 . HIS B 2 465 ? 116.292 136.130 92.716  1.00 79.88  ? 465 HIS D NE2 1 
ATOM   4759 N  N   . TRP B 2 466 ? 111.812 131.703 94.793  1.00 63.12  ? 466 TRP D N   1 
ATOM   4760 C  CA  . TRP B 2 466 ? 110.760 130.988 95.510  1.00 63.12  ? 466 TRP D CA  1 
ATOM   4761 C  C   . TRP B 2 466 ? 111.339 129.854 96.346  1.00 63.12  ? 466 TRP D C   1 
ATOM   4762 O  O   . TRP B 2 466 ? 111.013 129.708 97.532  1.00 63.12  ? 466 TRP D O   1 
ATOM   4763 C  CB  . TRP B 2 466 ? 109.733 130.454 94.509  1.00 63.12  ? 466 TRP D CB  1 
ATOM   4764 C  CG  . TRP B 2 466 ? 108.532 129.808 95.126  1.00 63.12  ? 466 TRP D CG  1 
ATOM   4765 C  CD1 . TRP B 2 466 ? 107.363 130.417 95.475  1.00 63.12  ? 466 TRP D CD1 1 
ATOM   4766 C  CD2 . TRP B 2 466 ? 108.375 128.423 95.451  1.00 63.12  ? 466 TRP D CD2 1 
ATOM   4767 N  NE1 . TRP B 2 466 ? 106.490 129.498 96.004  1.00 63.12  ? 466 TRP D NE1 1 
ATOM   4768 C  CE2 . TRP B 2 466 ? 107.088 128.266 96.000  1.00 63.12  ? 466 TRP D CE2 1 
ATOM   4769 C  CE3 . TRP B 2 466 ? 109.200 127.301 95.335  1.00 63.12  ? 466 TRP D CE3 1 
ATOM   4770 C  CZ2 . TRP B 2 466 ? 106.607 127.034 96.432  1.00 63.12  ? 466 TRP D CZ2 1 
ATOM   4771 C  CZ3 . TRP B 2 466 ? 108.719 126.078 95.764  1.00 63.12  ? 466 TRP D CZ3 1 
ATOM   4772 C  CH2 . TRP B 2 466 ? 107.436 125.955 96.306  1.00 63.12  ? 466 TRP D CH2 1 
ATOM   4773 N  N   . CYS B 2 467 ? 112.215 129.047 95.744  1.00 61.76  ? 467 CYS D N   1 
ATOM   4774 C  CA  . CYS B 2 467 ? 112.827 127.941 96.471  1.00 61.76  ? 467 CYS D CA  1 
ATOM   4775 C  C   . CYS B 2 467 ? 113.681 128.449 97.626  1.00 61.76  ? 467 CYS D C   1 
ATOM   4776 O  O   . CYS B 2 467 ? 113.658 127.885 98.726  1.00 61.76  ? 467 CYS D O   1 
ATOM   4777 C  CB  . CYS B 2 467 ? 113.662 127.086 95.517  1.00 61.76  ? 467 CYS D CB  1 
ATOM   4778 S  SG  . CYS B 2 467 ? 114.589 125.760 96.323  1.00 61.76  ? 467 CYS D SG  1 
ATOM   4779 N  N   . LYS B 2 468 ? 114.441 129.522 97.393  1.00 62.93  ? 468 LYS D N   1 
ATOM   4780 C  CA  . LYS B 2 468 ? 115.288 130.070 98.446  1.00 62.93  ? 468 LYS D CA  1 
ATOM   4781 C  C   . LYS B 2 468 ? 114.455 130.593 99.608  1.00 62.93  ? 468 LYS D C   1 
ATOM   4782 O  O   . LYS B 2 468 ? 114.792 130.362 100.773 1.00 62.93  ? 468 LYS D O   1 
ATOM   4783 C  CB  . LYS B 2 468 ? 116.177 131.177 97.879  1.00 62.93  ? 468 LYS D CB  1 
ATOM   4784 C  CG  . LYS B 2 468 ? 117.406 131.481 98.720  1.00 62.93  ? 468 LYS D CG  1 
ATOM   4785 C  CD  . LYS B 2 468 ? 118.296 132.506 98.038  1.00 62.93  ? 468 LYS D CD  1 
ATOM   4786 C  CE  . LYS B 2 468 ? 119.613 132.673 98.777  1.00 62.93  ? 468 LYS D CE  1 
ATOM   4787 N  NZ  . LYS B 2 468 ? 120.505 131.496 98.589  1.00 62.93  ? 468 LYS D NZ  1 
ATOM   4788 N  N   . VAL B 2 469 ? 113.358 131.294 99.310  1.00 59.10  ? 469 VAL D N   1 
ATOM   4789 C  CA  . VAL B 2 469 ? 112.494 131.814 100.366 1.00 59.10  ? 469 VAL D CA  1 
ATOM   4790 C  C   . VAL B 2 469 ? 111.879 130.668 101.158 1.00 59.10  ? 469 VAL D C   1 
ATOM   4791 O  O   . VAL B 2 469 ? 111.837 130.697 102.395 1.00 59.10  ? 469 VAL D O   1 
ATOM   4792 C  CB  . VAL B 2 469 ? 111.414 132.735 99.771  1.00 59.10  ? 469 VAL D CB  1 
ATOM   4793 C  CG1 . VAL B 2 469 ? 110.161 132.726 100.633 1.00 59.10  ? 469 VAL D CG1 1 
ATOM   4794 C  CG2 . VAL B 2 469 ? 111.948 134.146 99.628  1.00 59.10  ? 469 VAL D CG2 1 
ATOM   4795 N  N   . MET B 2 470 ? 111.393 129.641 100.456 1.00 52.61  ? 470 MET D N   1 
ATOM   4796 C  CA  . MET B 2 470 ? 110.784 128.508 101.146 1.00 52.61  ? 470 MET D CA  1 
ATOM   4797 C  C   . MET B 2 470 ? 111.789 127.809 102.052 1.00 52.61  ? 470 MET D C   1 
ATOM   4798 O  O   . MET B 2 470 ? 111.477 127.487 103.206 1.00 52.61  ? 470 MET D O   1 
ATOM   4799 C  CB  . MET B 2 470 ? 110.203 127.527 100.130 1.00 52.61  ? 470 MET D CB  1 
ATOM   4800 C  CG  . MET B 2 470 ? 108.769 127.824 99.735  1.00 52.61  ? 470 MET D CG  1 
ATOM   4801 S  SD  . MET B 2 470 ? 107.726 128.216 101.148 1.00 52.61  ? 470 MET D SD  1 
ATOM   4802 C  CE  . MET B 2 470 ? 106.116 128.271 100.369 1.00 52.61  ? 470 MET D CE  1 
ATOM   4803 N  N   . GLU B 2 471 ? 113.005 127.580 101.554 1.00 54.86  ? 471 GLU D N   1 
ATOM   4804 C  CA  . GLU B 2 471 ? 114.019 126.903 102.356 1.00 54.86  ? 471 GLU D CA  1 
ATOM   4805 C  C   . GLU B 2 471 ? 114.444 127.758 103.545 1.00 54.86  ? 471 GLU D C   1 
ATOM   4806 O  O   . GLU B 2 471 ? 114.667 127.240 104.645 1.00 54.86  ? 471 GLU D O   1 
ATOM   4807 C  CB  . GLU B 2 471 ? 115.225 126.547 101.488 1.00 54.86  ? 471 GLU D CB  1 
ATOM   4808 C  CG  . GLU B 2 471 ? 116.346 125.847 102.239 1.00 54.86  ? 471 GLU D CG  1 
ATOM   4809 C  CD  . GLU B 2 471 ? 115.926 124.501 102.798 1.00 54.86  ? 471 GLU D CD  1 
ATOM   4810 O  OE1 . GLU B 2 471 ? 115.039 123.856 102.201 1.00 54.86  ? 471 GLU D OE1 1 
ATOM   4811 O  OE2 . GLU B 2 471 ? 116.484 124.087 103.835 1.00 54.86  ? 471 GLU D OE2 1 
ATOM   4812 N  N   . ASN B 2 472 ? 114.570 129.071 103.341 1.00 56.07  ? 472 ASN D N   1 
ATOM   4813 C  CA  . ASN B 2 472 ? 114.986 129.952 104.427 1.00 56.07  ? 472 ASN D CA  1 
ATOM   4814 C  C   . ASN B 2 472 ? 113.923 130.031 105.515 1.00 56.07  ? 472 ASN D C   1 
ATOM   4815 O  O   . ASN B 2 472 ? 114.249 130.055 106.707 1.00 56.07  ? 472 ASN D O   1 
ATOM   4816 C  CB  . ASN B 2 472 ? 115.299 131.343 103.875 1.00 56.07  ? 472 ASN D CB  1 
ATOM   4817 C  CG  . ASN B 2 472 ? 116.171 132.160 104.807 1.00 56.07  ? 472 ASN D CG  1 
ATOM   4818 O  OD1 . ASN B 2 472 ? 116.281 131.864 105.996 1.00 56.07  ? 472 ASN D OD1 1 
ATOM   4819 N  ND2 . ASN B 2 472 ? 116.799 133.198 104.267 1.00 56.07  ? 472 ASN D ND2 1 
ATOM   4820 N  N   . VAL B 2 473 ? 112.646 130.069 105.129 1.00 55.28  ? 473 VAL D N   1 
ATOM   4821 C  CA  . VAL B 2 473 ? 111.585 130.212 106.120 1.00 55.28  ? 473 VAL D CA  1 
ATOM   4822 C  C   . VAL B 2 473 ? 111.321 128.884 106.820 1.00 55.28  ? 473 VAL D C   1 
ATOM   4823 O  O   . VAL B 2 473 ? 111.456 128.774 108.044 1.00 55.28  ? 473 VAL D O   1 
ATOM   4824 C  CB  . VAL B 2 473 ? 110.309 130.770 105.465 1.00 55.28  ? 473 VAL D CB  1 
ATOM   4825 C  CG1 . VAL B 2 473 ? 109.129 130.647 106.414 1.00 55.28  ? 473 VAL D CG1 1 
ATOM   4826 C  CG2 . VAL B 2 473 ? 110.516 132.219 105.056 1.00 55.28  ? 473 VAL D CG2 1 
ATOM   4827 N  N   . THR B 2 474 ? 110.943 127.857 106.059 1.00 47.10  ? 474 THR D N   1 
ATOM   4828 C  CA  . THR B 2 474 ? 110.551 126.587 106.659 1.00 47.10  ? 474 THR D CA  1 
ATOM   4829 C  C   . THR B 2 474 ? 111.725 125.799 107.222 1.00 47.10  ? 474 THR D C   1 
ATOM   4830 O  O   . THR B 2 474 ? 111.572 125.137 108.255 1.00 47.10  ? 474 THR D O   1 
ATOM   4831 C  CB  . THR B 2 474 ? 109.814 125.723 105.633 1.00 47.10  ? 474 THR D CB  1 
ATOM   4832 O  OG1 . THR B 2 474 ? 110.570 125.675 104.418 1.00 47.10  ? 474 THR D OG1 1 
ATOM   4833 C  CG2 . THR B 2 474 ? 108.443 126.304 105.346 1.00 47.10  ? 474 THR D CG2 1 
ATOM   4834 N  N   . LYS B 2 475 ? 112.887 125.856 106.572 1.00 51.88  ? 475 LYS D N   1 
ATOM   4835 C  CA  . LYS B 2 475 ? 114.078 125.106 106.971 1.00 51.88  ? 475 LYS D CA  1 
ATOM   4836 C  C   . LYS B 2 475 ? 113.814 123.608 107.078 1.00 51.88  ? 475 LYS D C   1 
ATOM   4837 O  O   . LYS B 2 475 ? 114.335 122.947 107.982 1.00 51.88  ? 475 LYS D O   1 
ATOM   4838 C  CB  . LYS B 2 475 ? 114.658 125.634 108.289 1.00 51.88  ? 475 LYS D CB  1 
ATOM   4839 C  CG  . LYS B 2 475 ? 114.634 127.147 108.423 1.00 51.88  ? 475 LYS D CG  1 
ATOM   4840 C  CD  . LYS B 2 475 ? 115.793 127.642 109.274 1.00 51.88  ? 475 LYS D CD  1 
ATOM   4841 C  CE  . LYS B 2 475 ? 115.513 127.447 110.755 1.00 51.88  ? 475 LYS D CE  1 
ATOM   4842 N  NZ  . LYS B 2 475 ? 116.489 128.181 111.607 1.00 51.88  ? 475 LYS D NZ  1 
ATOM   4843 N  N   . LEU B 2 476 ? 113.010 123.056 106.168 1.00 43.06  ? 476 LEU D N   1 
ATOM   4844 C  CA  . LEU B 2 476 ? 112.703 121.632 106.200 1.00 43.06  ? 476 LEU D CA  1 
ATOM   4845 C  C   . LEU B 2 476 ? 113.593 120.814 105.275 1.00 43.06  ? 476 LEU D C   1 
ATOM   4846 O  O   . LEU B 2 476 ? 113.671 119.591 105.436 1.00 43.06  ? 476 LEU D O   1 
ATOM   4847 C  CB  . LEU B 2 476 ? 111.234 121.403 105.835 1.00 43.06  ? 476 LEU D CB  1 
ATOM   4848 C  CG  . LEU B 2 476 ? 110.200 122.010 106.784 1.00 43.06  ? 476 LEU D CG  1 
ATOM   4849 C  CD1 . LEU B 2 476 ? 108.789 121.716 106.304 1.00 43.06  ? 476 LEU D CD1 1 
ATOM   4850 C  CD2 . LEU B 2 476 ? 110.406 121.493 108.194 1.00 43.06  ? 476 LEU D CD2 1 
ATOM   4851 N  N   . GLY B 2 477 ? 114.262 121.451 104.316 1.00 42.37  ? 477 GLY D N   1 
ATOM   4852 C  CA  . GLY B 2 477 ? 115.135 120.727 103.413 1.00 42.37  ? 477 GLY D CA  1 
ATOM   4853 C  C   . GLY B 2 477 ? 114.428 119.858 102.400 1.00 42.37  ? 477 GLY D C   1 
ATOM   4854 O  O   . GLY B 2 477 ? 115.029 118.914 101.882 1.00 42.37  ? 477 GLY D O   1 
ATOM   4855 N  N   . LEU B 2 478 ? 113.165 120.147 102.102 1.00 41.06  ? 478 LEU D N   1 
ATOM   4856 C  CA  . LEU B 2 478 ? 112.415 119.358 101.143 1.00 41.06  ? 478 LEU D CA  1 
ATOM   4857 C  C   . LEU B 2 478 ? 112.816 119.720 99.713  1.00 41.06  ? 478 LEU D C   1 
ATOM   4858 O  O   . LEU B 2 478 ? 113.313 120.818 99.455  1.00 41.06  ? 478 LEU D O   1 
ATOM   4859 C  CB  . LEU B 2 478 ? 110.918 119.579 101.338 1.00 41.06  ? 478 LEU D CB  1 
ATOM   4860 C  CG  . LEU B 2 478 ? 110.339 119.131 102.679 1.00 41.06  ? 478 LEU D CG  1 
ATOM   4861 C  CD1 . LEU B 2 478 ? 108.877 119.525 102.783 1.00 41.06  ? 478 LEU D CD1 1 
ATOM   4862 C  CD2 . LEU B 2 478 ? 110.505 117.635 102.849 1.00 41.06  ? 478 LEU D CD2 1 
ATOM   4863 N  N   . PRO B 2 479 ? 112.607 118.804 98.760  1.00 43.80  ? 479 PRO D N   1 
ATOM   4864 C  CA  . PRO B 2 479 ? 112.836 119.125 97.333  1.00 43.80  ? 479 PRO D CA  1 
ATOM   4865 C  C   . PRO B 2 479 ? 111.728 120.010 96.774  1.00 43.80  ? 479 PRO D C   1 
ATOM   4866 O  O   . PRO B 2 479 ? 110.749 119.556 96.174  1.00 43.80  ? 479 PRO D O   1 
ATOM   4867 C  CB  . PRO B 2 479 ? 112.877 117.736 96.688  1.00 43.80  ? 479 PRO D CB  1 
ATOM   4868 C  CG  . PRO B 2 479 ? 112.012 116.899 97.559  1.00 43.80  ? 479 PRO D CG  1 
ATOM   4869 C  CD  . PRO B 2 479 ? 112.256 117.386 98.956  1.00 43.80  ? 479 PRO D CD  1 
ATOM   4870 N  N   . TRP B 2 480 ? 111.884 121.319 96.983  1.00 46.82  ? 480 TRP D N   1 
ATOM   4871 C  CA  . TRP B 2 480 ? 110.801 122.259 96.709  1.00 46.82  ? 480 TRP D CA  1 
ATOM   4872 C  C   . TRP B 2 480 ? 110.457 122.320 95.226  1.00 46.82  ? 480 TRP D C   1 
ATOM   4873 O  O   . TRP B 2 480 ? 109.285 122.477 94.863  1.00 46.82  ? 480 TRP D O   1 
ATOM   4874 C  CB  . TRP B 2 480 ? 111.172 123.645 97.232  1.00 46.82  ? 480 TRP D CB  1 
ATOM   4875 C  CG  . TRP B 2 480 ? 111.311 123.689 98.719  1.00 46.82  ? 480 TRP D CG  1 
ATOM   4876 C  CD1 . TRP B 2 480 ? 112.458 123.884 99.429  1.00 46.82  ? 480 TRP D CD1 1 
ATOM   4877 C  CD2 . TRP B 2 480 ? 110.266 123.521 99.682  1.00 46.82  ? 480 TRP D CD2 1 
ATOM   4878 N  NE1 . TRP B 2 480 ? 112.191 123.854 100.775 1.00 46.82  ? 480 TRP D NE1 1 
ATOM   4879 C  CE2 . TRP B 2 480 ? 110.851 123.633 100.957 1.00 46.82  ? 480 TRP D CE2 1 
ATOM   4880 C  CE3 . TRP B 2 480 ? 108.891 123.291 99.590  1.00 46.82  ? 480 TRP D CE3 1 
ATOM   4881 C  CZ2 . TRP B 2 480 ? 110.111 123.521 102.129 1.00 46.82  ? 480 TRP D CZ2 1 
ATOM   4882 C  CZ3 . TRP B 2 480 ? 108.158 123.181 100.755 1.00 46.82  ? 480 TRP D CZ3 1 
ATOM   4883 C  CH2 . TRP B 2 480 ? 108.769 123.296 102.007 1.00 46.82  ? 480 TRP D CH2 1 
ATOM   4884 N  N   . ARG B 2 481 ? 111.461 122.212 94.351  1.00 57.90  ? 481 ARG D N   1 
ATOM   4885 C  CA  . ARG B 2 481 ? 111.202 122.333 92.919  1.00 57.90  ? 481 ARG D CA  1 
ATOM   4886 C  C   . ARG B 2 481 ? 110.252 121.253 92.418  1.00 57.90  ? 481 ARG D C   1 
ATOM   4887 O  O   . ARG B 2 481 ? 109.511 121.482 91.455  1.00 57.90  ? 481 ARG D O   1 
ATOM   4888 C  CB  . ARG B 2 481 ? 112.514 122.292 92.137  1.00 57.90  ? 481 ARG D CB  1 
ATOM   4889 C  CG  . ARG B 2 481 ? 113.204 123.641 92.029  1.00 57.90  ? 481 ARG D CG  1 
ATOM   4890 C  CD  . ARG B 2 481 ? 114.471 123.554 91.195  1.00 57.90  ? 481 ARG D CD  1 
ATOM   4891 N  NE  . ARG B 2 481 ? 115.127 124.850 91.064  1.00 57.90  ? 481 ARG D NE  1 
ATOM   4892 C  CZ  . ARG B 2 481 ? 115.891 125.401 91.997  1.00 57.90  ? 481 ARG D CZ  1 
ATOM   4893 N  NH1 . ARG B 2 481 ? 116.123 124.793 93.149  1.00 57.90  ? 481 ARG D NH1 1 
ATOM   4894 N  NH2 . ARG B 2 481 ? 116.437 126.591 91.768  1.00 57.90  ? 481 ARG D NH2 1 
ATOM   4895 N  N   . LEU B 2 482 ? 110.254 120.078 93.050  1.00 52.98  ? 482 LEU D N   1 
ATOM   4896 C  CA  . LEU B 2 482 ? 109.299 119.039 92.682  1.00 52.98  ? 482 LEU D CA  1 
ATOM   4897 C  C   . LEU B 2 482 ? 107.898 119.349 93.191  1.00 52.98  ? 482 LEU D C   1 
ATOM   4898 O  O   . LEU B 2 482 ? 106.917 118.831 92.646  1.00 52.98  ? 482 LEU D O   1 
ATOM   4899 C  CB  . LEU B 2 482 ? 109.762 117.684 93.216  1.00 52.98  ? 482 LEU D CB  1 
ATOM   4900 C  CG  . LEU B 2 482 ? 110.455 116.749 92.223  1.00 52.98  ? 482 LEU D CG  1 
ATOM   4901 C  CD1 . LEU B 2 482 ? 111.585 117.462 91.499  1.00 52.98  ? 482 LEU D CD1 1 
ATOM   4902 C  CD2 . LEU B 2 482 ? 110.970 115.511 92.936  1.00 52.98  ? 482 LEU D CD2 1 
ATOM   4903 N  N   . LEU B 2 483 ? 107.783 120.182 94.225  1.00 51.83  ? 483 LEU D N   1 
ATOM   4904 C  CA  . LEU B 2 483 ? 106.489 120.542 94.788  1.00 51.83  ? 483 LEU D CA  1 
ATOM   4905 C  C   . LEU B 2 483 ? 105.928 121.836 94.214  1.00 51.83  ? 483 LEU D C   1 
ATOM   4906 O  O   . LEU B 2 483 ? 104.891 122.306 94.695  1.00 51.83  ? 483 LEU D O   1 
ATOM   4907 C  CB  . LEU B 2 483 ? 106.591 120.668 96.309  1.00 51.83  ? 483 LEU D CB  1 
ATOM   4908 C  CG  . LEU B 2 483 ? 106.456 119.387 97.132  1.00 51.83  ? 483 LEU D CG  1 
ATOM   4909 C  CD1 . LEU B 2 483 ? 107.781 118.653 97.211  1.00 51.83  ? 483 LEU D CD1 1 
ATOM   4910 C  CD2 . LEU B 2 483 ? 105.940 119.710 98.521  1.00 51.83  ? 483 LEU D CD2 1 
ATOM   4911 N  N   . ARG B 2 484 ? 106.587 122.422 93.213  1.00 69.60  ? 484 ARG D N   1 
ATOM   4912 C  CA  . ARG B 2 484 ? 106.151 123.704 92.669  1.00 69.60  ? 484 ARG D CA  1 
ATOM   4913 C  C   . ARG B 2 484 ? 104.753 123.604 92.069  1.00 69.60  ? 484 ARG D C   1 
ATOM   4914 O  O   . ARG B 2 484 ? 103.914 124.491 92.259  1.00 69.60  ? 484 ARG D O   1 
ATOM   4915 C  CB  . ARG B 2 484 ? 107.156 124.189 91.623  1.00 69.60  ? 484 ARG D CB  1 
ATOM   4916 C  CG  . ARG B 2 484 ? 106.578 125.151 90.601  1.00 69.60  ? 484 ARG D CG  1 
ATOM   4917 C  CD  . ARG B 2 484 ? 107.668 125.725 89.714  1.00 69.60  ? 484 ARG D CD  1 
ATOM   4918 N  NE  . ARG B 2 484 ? 108.392 124.679 89.002  1.00 69.60  ? 484 ARG D NE  1 
ATOM   4919 C  CZ  . ARG B 2 484 ? 108.774 124.762 87.735  1.00 69.60  ? 484 ARG D CZ  1 
ATOM   4920 N  NH1 . ARG B 2 484 ? 108.516 125.833 87.004  1.00 69.60  ? 484 ARG D NH1 1 
ATOM   4921 N  NH2 . ARG B 2 484 ? 109.431 123.743 87.188  1.00 69.60  ? 484 ARG D NH2 1 
ATOM   4922 N  N   . ASP B 2 485 ? 104.484 122.521 91.348  1.00 68.71  ? 485 ASP D N   1 
ATOM   4923 C  CA  . ASP B 2 485 ? 103.197 122.349 90.677  1.00 68.71  ? 485 ASP D CA  1 
ATOM   4924 C  C   . ASP B 2 485 ? 102.082 121.894 91.612  1.00 68.71  ? 485 ASP D C   1 
ATOM   4925 O  O   . ASP B 2 485 ? 100.929 121.835 91.165  1.00 68.71  ? 485 ASP D O   1 
ATOM   4926 C  CB  . ASP B 2 485 ? 103.343 121.362 89.518  1.00 68.71  ? 485 ASP D CB  1 
ATOM   4927 C  CG  . ASP B 2 485 ? 104.069 120.092 89.920  1.00 68.71  ? 485 ASP D CG  1 
ATOM   4928 O  OD1 . ASP B 2 485 ? 104.294 119.890 91.131  1.00 68.71  ? 485 ASP D OD1 1 
ATOM   4929 O  OD2 . ASP B 2 485 ? 104.416 119.296 89.022  1.00 68.71  ? 485 ASP D OD2 1 
ATOM   4930 N  N   . LYS B 2 486 ? 102.362 121.574 92.871  1.00 64.37  ? 486 LYS D N   1 
ATOM   4931 C  CA  . LYS B 2 486 ? 101.330 121.163 93.816  1.00 64.37  ? 486 LYS D CA  1 
ATOM   4932 C  C   . LYS B 2 486 ? 101.039 122.209 94.878  1.00 64.37  ? 486 LYS D C   1 
ATOM   4933 O  O   . LYS B 2 486 ? 99.871  122.454 95.189  1.00 64.37  ? 486 LYS D O   1 
ATOM   4934 C  CB  . LYS B 2 486 ? 101.726 119.842 94.488  1.00 64.37  ? 486 LYS D CB  1 
ATOM   4935 C  CG  . LYS B 2 486 ? 102.394 118.856 93.547  1.00 64.37  ? 486 LYS D CG  1 
ATOM   4936 C  CD  . LYS B 2 486 ? 102.384 117.449 94.115  1.00 64.37  ? 486 LYS D CD  1 
ATOM   4937 C  CE  . LYS B 2 486 ? 103.311 116.535 93.332  1.00 64.37  ? 486 LYS D CE  1 
ATOM   4938 N  NZ  . LYS B 2 486 ? 103.052 116.614 91.868  1.00 64.37  ? 486 LYS D NZ  1 
ATOM   4939 N  N   . LEU B 2 487 ? 102.070 122.832 95.451  1.00 62.59  ? 487 LEU D N   1 
ATOM   4940 C  CA  . LEU B 2 487 ? 101.842 123.924 96.391  1.00 62.59  ? 487 LEU D CA  1 
ATOM   4941 C  C   . LEU B 2 487 ? 101.345 125.174 95.675  1.00 62.59  ? 487 LEU D C   1 
ATOM   4942 O  O   . LEU B 2 487 ? 100.504 125.906 96.209  1.00 62.59  ? 487 LEU D O   1 
ATOM   4943 C  CB  . LEU B 2 487 ? 103.122 124.227 97.170  1.00 62.59  ? 487 LEU D CB  1 
ATOM   4944 C  CG  . LEU B 2 487 ? 103.525 123.201 98.231  1.00 62.59  ? 487 LEU D CG  1 
ATOM   4945 C  CD1 . LEU B 2 487 ? 104.886 123.538 98.815  1.00 62.59  ? 487 LEU D CD1 1 
ATOM   4946 C  CD2 . LEU B 2 487 ? 102.477 123.126 99.326  1.00 62.59  ? 487 LEU D CD2 1 
ATOM   4947 N  N   . ALA B 2 488 ? 101.851 125.430 94.469  1.00 75.96  ? 488 ALA D N   1 
ATOM   4948 C  CA  . ALA B 2 488 ? 101.437 126.560 93.640  1.00 75.96  ? 488 ALA D CA  1 
ATOM   4949 C  C   . ALA B 2 488 ? 101.083 126.041 92.251  1.00 75.96  ? 488 ALA D C   1 
ATOM   4950 O  O   . ALA B 2 488 ? 101.883 126.149 91.311  1.00 75.96  ? 488 ALA D O   1 
ATOM   4951 C  CB  . ALA B 2 488 ? 102.527 127.626 93.564  1.00 75.96  ? 488 ALA D CB  1 
ATOM   4952 N  N   . PRO B 2 489 ? 99.891  125.470 92.087  1.00 85.62  ? 489 PRO D N   1 
ATOM   4953 C  CA  . PRO B 2 489 ? 99.523  124.887 90.793  1.00 85.62  ? 489 PRO D CA  1 
ATOM   4954 C  C   . PRO B 2 489 ? 99.331  125.955 89.726  1.00 85.62  ? 489 PRO D C   1 
ATOM   4955 O  O   . PRO B 2 489 ? 99.140  127.138 90.013  1.00 85.62  ? 489 PRO D O   1 
ATOM   4956 C  CB  . PRO B 2 489 ? 98.208  124.159 91.095  1.00 85.62  ? 489 PRO D CB  1 
ATOM   4957 C  CG  . PRO B 2 489 ? 97.636  124.903 92.255  1.00 85.62  ? 489 PRO D CG  1 
ATOM   4958 C  CD  . PRO B 2 489 ? 98.813  125.339 93.082  1.00 85.62  ? 489 PRO D CD  1 
ATOM   4959 N  N   . GLY B 2 490 ? 99.391  125.515 88.471  1.00 99.47  ? 490 GLY D N   1 
ATOM   4960 C  CA  . GLY B 2 490 ? 99.200  126.406 87.344  1.00 99.47  ? 490 GLY D CA  1 
ATOM   4961 C  C   . GLY B 2 490 ? 100.262 127.479 87.229  1.00 99.47  ? 490 GLY D C   1 
ATOM   4962 O  O   . GLY B 2 490 ? 99.947  128.655 87.024  1.00 99.47  ? 490 GLY D O   1 
ATOM   4963 N  N   . THR B 2 491 ? 101.526 127.087 87.362  1.00 100.93 ? 491 THR D N   1 
ATOM   4964 C  CA  . THR B 2 491 ? 102.647 128.011 87.286  1.00 100.93 ? 491 THR D CA  1 
ATOM   4965 C  C   . THR B 2 491 ? 103.558 127.620 86.132  1.00 100.93 ? 491 THR D C   1 
ATOM   4966 O  O   . THR B 2 491 ? 103.741 126.433 85.848  1.00 100.93 ? 491 THR D O   1 
ATOM   4967 C  CB  . THR B 2 491 ? 103.443 128.035 88.594  1.00 100.93 ? 491 THR D CB  1 
ATOM   4968 O  OG1 . THR B 2 491 ? 103.685 126.693 89.034  1.00 100.93 ? 491 THR D OG1 1 
ATOM   4969 C  CG2 . THR B 2 491 ? 102.673 128.789 89.667  1.00 100.93 ? 491 THR D CG2 1 
ATOM   4970 N  N   . ASP B 2 492 ? 104.126 128.626 85.473  1.00 104.31 ? 492 ASP D N   1 
ATOM   4971 C  CA  . ASP B 2 492 ? 104.987 128.402 84.325  1.00 104.31 ? 492 ASP D CA  1 
ATOM   4972 C  C   . ASP B 2 492 ? 106.386 127.978 84.771  1.00 104.31 ? 492 ASP D C   1 
ATOM   4973 O  O   . ASP B 2 492 ? 106.643 127.707 85.947  1.00 104.31 ? 492 ASP D O   1 
ATOM   4974 C  CB  . ASP B 2 492 ? 105.058 129.657 83.458  1.00 104.31 ? 492 ASP D CB  1 
ATOM   4975 C  CG  . ASP B 2 492 ? 103.698 130.088 82.949  1.00 104.31 ? 492 ASP D CG  1 
ATOM   4976 O  OD1 . ASP B 2 492 ? 102.813 129.218 82.807  1.00 104.31 ? 492 ASP D OD1 1 
ATOM   4977 O  OD2 . ASP B 2 492 ? 103.512 131.296 82.692  1.00 104.31 ? 492 ASP D OD2 1 
ATOM   4978 N  N   . SER B 2 493 ? 107.301 127.924 83.802  1.00 104.16 ? 493 SER D N   1 
ATOM   4979 C  CA  . SER B 2 493 ? 108.634 127.397 84.067  1.00 104.16 ? 493 SER D CA  1 
ATOM   4980 C  C   . SER B 2 493 ? 109.602 128.461 84.567  1.00 104.16 ? 493 SER D C   1 
ATOM   4981 O  O   . SER B 2 493 ? 110.749 128.133 84.888  1.00 104.16 ? 493 SER D O   1 
ATOM   4982 C  CB  . SER B 2 493 ? 109.196 126.741 82.805  1.00 104.16 ? 493 SER D CB  1 
ATOM   4983 O  OG  . SER B 2 493 ? 108.264 125.833 82.245  1.00 104.16 ? 493 SER D OG  1 
ATOM   4984 N  N   . GLN B 2 494 ? 109.177 129.724 84.642  1.00 106.25 ? 494 GLN D N   1 
ATOM   4985 C  CA  . GLN B 2 494 ? 110.074 130.804 85.024  1.00 106.25 ? 494 GLN D CA  1 
ATOM   4986 C  C   . GLN B 2 494 ? 109.596 131.641 86.201  1.00 106.25 ? 494 GLN D C   1 
ATOM   4987 O  O   . GLN B 2 494 ? 110.438 132.110 86.974  1.00 106.25 ? 494 GLN D O   1 
ATOM   4988 C  CB  . GLN B 2 494 ? 110.325 131.741 83.831  1.00 106.25 ? 494 GLN D CB  1 
ATOM   4989 C  CG  . GLN B 2 494 ? 111.088 131.096 82.683  1.00 106.25 ? 494 GLN D CG  1 
ATOM   4990 C  CD  . GLN B 2 494 ? 112.547 130.842 83.016  1.00 106.25 ? 494 GLN D CD  1 
ATOM   4991 O  OE1 . GLN B 2 494 ? 113.067 131.345 84.013  1.00 106.25 ? 494 GLN D OE1 1 
ATOM   4992 N  NE2 . GLN B 2 494 ? 113.215 130.057 82.180  1.00 106.25 ? 494 GLN D NE2 1 
ATOM   4993 N  N   . LYS B 2 495 ? 108.291 131.842 86.366  1.00 100.05 ? 495 LYS D N   1 
ATOM   4994 C  CA  . LYS B 2 495 ? 107.794 132.701 87.430  1.00 100.05 ? 495 LYS D CA  1 
ATOM   4995 C  C   . LYS B 2 495 ? 106.648 132.012 88.156  1.00 100.05 ? 495 LYS D C   1 
ATOM   4996 O  O   . LYS B 2 495 ? 105.858 131.281 87.552  1.00 100.05 ? 495 LYS D O   1 
ATOM   4997 C  CB  . LYS B 2 495 ? 107.344 134.061 86.884  1.00 100.05 ? 495 LYS D CB  1 
ATOM   4998 C  CG  . LYS B 2 495 ? 106.244 133.981 85.840  1.00 100.05 ? 495 LYS D CG  1 
ATOM   4999 C  CD  . LYS B 2 495 ? 105.870 135.363 85.328  1.00 100.05 ? 495 LYS D CD  1 
ATOM   5000 C  CE  . LYS B 2 495 ? 107.038 136.022 84.613  1.00 100.05 ? 495 LYS D CE  1 
ATOM   5001 N  NZ  . LYS B 2 495 ? 106.650 137.323 84.001  1.00 100.05 ? 495 LYS D NZ  1 
ATOM   5002 N  N   . VAL B 2 496 ? 106.572 132.254 89.463  1.00 91.53  ? 496 VAL D N   1 
ATOM   5003 C  CA  . VAL B 2 496 ? 105.529 131.704 90.319  1.00 91.53  ? 496 VAL D CA  1 
ATOM   5004 C  C   . VAL B 2 496 ? 104.911 132.842 91.117  1.00 91.53  ? 496 VAL D C   1 
ATOM   5005 O  O   . VAL B 2 496 ? 105.626 133.624 91.754  1.00 91.53  ? 496 VAL D O   1 
ATOM   5006 C  CB  . VAL B 2 496 ? 106.083 130.617 91.265  1.00 91.53  ? 496 VAL D CB  1 
ATOM   5007 C  CG1 . VAL B 2 496 ? 105.165 130.430 92.464  1.00 91.53  ? 496 VAL D CG1 1 
ATOM   5008 C  CG2 . VAL B 2 496 ? 106.262 129.307 90.522  1.00 91.53  ? 496 VAL D CG2 1 
ATOM   5009 N  N   . ASN B 2 497 ? 103.585 132.937 91.082  1.00 95.84  ? 497 ASN D N   1 
ATOM   5010 C  CA  . ASN B 2 497 ? 102.885 133.950 91.859  1.00 95.84  ? 497 ASN D CA  1 
ATOM   5011 C  C   . ASN B 2 497 ? 102.697 133.465 93.291  1.00 95.84  ? 497 ASN D C   1 
ATOM   5012 O  O   . ASN B 2 497 ? 102.274 132.328 93.524  1.00 95.84  ? 497 ASN D O   1 
ATOM   5013 C  CB  . ASN B 2 497 ? 101.539 134.288 91.216  1.00 95.84  ? 497 ASN D CB  1 
ATOM   5014 C  CG  . ASN B 2 497 ? 100.556 133.137 91.268  1.00 95.84  ? 497 ASN D CG  1 
ATOM   5015 O  OD1 . ASN B 2 497 ? 99.836  132.964 92.251  1.00 95.84  ? 497 ASN D OD1 1 
ATOM   5016 N  ND2 . ASN B 2 497 ? 100.519 132.342 90.205  1.00 95.84  ? 497 ASN D ND2 1 
ATOM   5017 N  N   . TYR B 2 498 ? 103.030 134.327 94.254  1.00 95.07  ? 498 TYR D N   1 
ATOM   5018 C  CA  . TYR B 2 498 ? 102.917 133.938 95.654  1.00 95.07  ? 498 TYR D CA  1 
ATOM   5019 C  C   . TYR B 2 498 ? 101.488 134.069 96.161  1.00 95.07  ? 498 TYR D C   1 
ATOM   5020 O  O   . TYR B 2 498 ? 101.175 133.587 97.255  1.00 95.07  ? 498 TYR D O   1 
ATOM   5021 C  CB  . TYR B 2 498 ? 103.861 134.778 96.515  1.00 95.07  ? 498 TYR D CB  1 
ATOM   5022 C  CG  . TYR B 2 498 ? 103.966 136.225 96.090  1.00 95.07  ? 498 TYR D CG  1 
ATOM   5023 C  CD1 . TYR B 2 498 ? 102.881 137.084 96.208  1.00 95.07  ? 498 TYR D CD1 1 
ATOM   5024 C  CD2 . TYR B 2 498 ? 105.151 136.734 95.579  1.00 95.07  ? 498 TYR D CD2 1 
ATOM   5025 C  CE1 . TYR B 2 498 ? 102.972 138.407 95.824  1.00 95.07  ? 498 TYR D CE1 1 
ATOM   5026 C  CE2 . TYR B 2 498 ? 105.251 138.056 95.192  1.00 95.07  ? 498 TYR D CE2 1 
ATOM   5027 C  CZ  . TYR B 2 498 ? 104.160 138.888 95.317  1.00 95.07  ? 498 TYR D CZ  1 
ATOM   5028 O  OH  . TYR B 2 498 ? 104.257 140.205 94.933  1.00 95.07  ? 498 TYR D OH  1 
ATOM   5029 N  N   . ASN B 2 499 ? 100.615 134.727 95.394  1.00 95.97  ? 499 ASN D N   1 
ATOM   5030 C  CA  . ASN B 2 499 ? 99.234  134.901 95.830  1.00 95.97  ? 499 ASN D CA  1 
ATOM   5031 C  C   . ASN B 2 499 ? 98.521  133.561 95.956  1.00 95.97  ? 499 ASN D C   1 
ATOM   5032 O  O   . ASN B 2 499 ? 97.786  133.329 96.924  1.00 95.97  ? 499 ASN D O   1 
ATOM   5033 C  CB  . ASN B 2 499 ? 98.490  135.818 94.860  1.00 95.97  ? 499 ASN D CB  1 
ATOM   5034 C  CG  . ASN B 2 499 ? 99.102  137.202 94.784  1.00 95.97  ? 499 ASN D CG  1 
ATOM   5035 O  OD1 . ASN B 2 499 ? 99.730  137.561 93.788  1.00 95.97  ? 499 ASN D OD1 1 
ATOM   5036 N  ND2 . ASN B 2 499 ? 98.926  137.985 95.841  1.00 95.97  ? 499 ASN D ND2 1 
ATOM   5037 N  N   . ARG B 2 500 ? 98.722  132.665 94.986  1.00 91.23  ? 500 ARG D N   1 
ATOM   5038 C  CA  . ARG B 2 500 ? 98.117  131.341 95.075  1.00 91.23  ? 500 ARG D CA  1 
ATOM   5039 C  C   . ARG B 2 500 ? 98.676  130.548 96.247  1.00 91.23  ? 500 ARG D C   1 
ATOM   5040 O  O   . ARG B 2 500 ? 97.926  129.846 96.934  1.00 91.23  ? 500 ARG D O   1 
ATOM   5041 C  CB  . ARG B 2 500 ? 98.324  130.571 93.772  1.00 91.23  ? 500 ARG D CB  1 
ATOM   5042 C  CG  . ARG B 2 500 ? 97.270  129.506 93.520  1.00 91.23  ? 500 ARG D CG  1 
ATOM   5043 C  CD  . ARG B 2 500 ? 97.557  128.732 92.248  1.00 91.23  ? 500 ARG D CD  1 
ATOM   5044 N  NE  . ARG B 2 500 ? 98.063  129.591 91.184  1.00 91.23  ? 500 ARG D NE  1 
ATOM   5045 C  CZ  . ARG B 2 500 ? 97.475  129.749 90.006  1.00 91.23  ? 500 ARG D CZ  1 
ATOM   5046 N  NH1 . ARG B 2 500 ? 96.352  129.119 89.704  1.00 91.23  ? 500 ARG D NH1 1 
ATOM   5047 N  NH2 . ARG B 2 500 ? 98.029  130.558 89.108  1.00 91.23  ? 500 ARG D NH2 1 
ATOM   5048 N  N   . THR B 2 501 ? 99.986  130.640 96.486  1.00 87.21  ? 501 THR D N   1 
ATOM   5049 C  CA  . THR B 2 501 ? 100.583 129.928 97.610  1.00 87.21  ? 501 THR D CA  1 
ATOM   5050 C  C   . THR B 2 501 ? 100.007 130.417 98.932  1.00 87.21  ? 501 THR D C   1 
ATOM   5051 O  O   . THR B 2 501 ? 99.587  129.615 99.772  1.00 87.21  ? 501 THR D O   1 
ATOM   5052 C  CB  . THR B 2 501 ? 102.103 130.093 97.594  1.00 87.21  ? 501 THR D CB  1 
ATOM   5053 O  OG1 . THR B 2 501 ? 102.611 129.731 96.305  1.00 87.21  ? 501 THR D OG1 1 
ATOM   5054 C  CG2 . THR B 2 501 ? 102.743 129.209 98.653  1.00 87.21  ? 501 THR D CG2 1 
ATOM   5055 N  N   . LEU B 2 502 ? 99.958  131.738 99.122  1.00 88.75  ? 502 LEU D N   1 
ATOM   5056 C  CA  . LEU B 2 502 ? 99.438  132.296 100.367 1.00 88.75  ? 502 LEU D CA  1 
ATOM   5057 C  C   . LEU B 2 502 ? 97.976  131.923 100.576 1.00 88.75  ? 502 LEU D C   1 
ATOM   5058 O  O   . LEU B 2 502 ? 97.528  131.759 101.717 1.00 88.75  ? 502 LEU D O   1 
ATOM   5059 C  CB  . LEU B 2 502 ? 99.610  133.815 100.375 1.00 88.75  ? 502 LEU D CB  1 
ATOM   5060 C  CG  . LEU B 2 502 ? 100.807 134.373 101.147 1.00 88.75  ? 502 LEU D CG  1 
ATOM   5061 C  CD1 . LEU B 2 502 ? 100.669 134.078 102.632 1.00 88.75  ? 502 LEU D CD1 1 
ATOM   5062 C  CD2 . LEU B 2 502 ? 102.113 133.816 100.605 1.00 88.75  ? 502 LEU D CD2 1 
ATOM   5063 N  N   . ASP B 2 503 ? 97.215  131.790 99.487  1.00 92.50  ? 503 ASP D N   1 
ATOM   5064 C  CA  . ASP B 2 503 ? 95.817  131.394 99.608  1.00 92.50  ? 503 ASP D CA  1 
ATOM   5065 C  C   . ASP B 2 503 ? 95.690  129.975 100.148 1.00 92.50  ? 503 ASP D C   1 
ATOM   5066 O  O   . ASP B 2 503 ? 94.704  129.644 100.818 1.00 92.50  ? 503 ASP D O   1 
ATOM   5067 C  CB  . ASP B 2 503 ? 95.118  131.517 98.254  1.00 92.50  ? 503 ASP D CB  1 
ATOM   5068 C  CG  . ASP B 2 503 ? 94.769  132.950 97.906  1.00 92.50  ? 503 ASP D CG  1 
ATOM   5069 O  OD1 . ASP B 2 503 ? 94.798  133.808 98.813  1.00 92.50  ? 503 ASP D OD1 1 
ATOM   5070 O  OD2 . ASP B 2 503 ? 94.466  133.220 96.725  1.00 92.50  ? 503 ASP D OD2 1 
ATOM   5071 N  N   . LEU B 2 504 ? 96.675  129.121 99.862  1.00 83.26  ? 504 LEU D N   1 
ATOM   5072 C  CA  . LEU B 2 504 ? 96.601  127.728 100.292 1.00 83.26  ? 504 LEU D CA  1 
ATOM   5073 C  C   . LEU B 2 504 ? 96.631  127.614 101.812 1.00 83.26  ? 504 LEU D C   1 
ATOM   5074 O  O   . LEU B 2 504 ? 95.853  126.856 102.404 1.00 83.26  ? 504 LEU D O   1 
ATOM   5075 C  CB  . LEU B 2 504 ? 97.742  126.925 99.666  1.00 83.26  ? 504 LEU D CB  1 
ATOM   5076 C  CG  . LEU B 2 504 ? 97.832  125.456 100.079 1.00 83.26  ? 504 LEU D CG  1 
ATOM   5077 C  CD1 . LEU B 2 504 ? 96.560  124.717 99.700  1.00 83.26  ? 504 LEU D CD1 1 
ATOM   5078 C  CD2 . LEU B 2 504 ? 99.046  124.793 99.450  1.00 83.26  ? 504 LEU D CD2 1 
ATOM   5079 N  N   . LEU B 2 505 ? 97.524  128.362 102.467 1.00 83.86  ? 505 LEU D N   1 
ATOM   5080 C  CA  . LEU B 2 505 ? 97.590  128.297 103.924 1.00 83.86  ? 505 LEU D CA  1 
ATOM   5081 C  C   . LEU B 2 505 ? 96.476  129.106 104.573 1.00 83.86  ? 505 LEU D C   1 
ATOM   5082 O  O   . LEU B 2 505 ? 96.237  128.976 105.779 1.00 83.86  ? 505 LEU D O   1 
ATOM   5083 C  CB  . LEU B 2 505 ? 98.950  128.781 104.433 1.00 83.86  ? 505 LEU D CB  1 
ATOM   5084 C  CG  . LEU B 2 505 ? 100.240 128.402 103.702 1.00 83.86  ? 505 LEU D CG  1 
ATOM   5085 C  CD1 . LEU B 2 505 ? 100.593 129.429 102.649 1.00 83.86  ? 505 LEU D CD1 1 
ATOM   5086 C  CD2 . LEU B 2 505 ? 101.382 128.238 104.685 1.00 83.86  ? 505 LEU D CD2 1 
ATOM   5087 N  N   . ASP B 2 506 ? 95.788  129.942 103.801 1.00 99.13  ? 506 ASP D N   1 
ATOM   5088 C  CA  . ASP B 2 506 ? 94.705  130.764 104.322 1.00 99.13  ? 506 ASP D CA  1 
ATOM   5089 C  C   . ASP B 2 506 ? 93.343  130.089 104.209 1.00 99.13  ? 506 ASP D C   1 
ATOM   5090 O  O   . ASP B 2 506 ? 92.333  130.700 104.573 1.00 99.13  ? 506 ASP D O   1 
ATOM   5091 C  CB  . ASP B 2 506 ? 94.675  132.115 103.599 1.00 99.13  ? 506 ASP D CB  1 
ATOM   5092 C  CG  . ASP B 2 506 ? 93.975  133.192 104.404 1.00 99.13  ? 506 ASP D CG  1 
ATOM   5093 O  OD1 . ASP B 2 506 ? 94.256  133.305 105.616 1.00 99.13  ? 506 ASP D OD1 1 
ATOM   5094 O  OD2 . ASP B 2 506 ? 93.145  133.924 103.827 1.00 99.13  ? 506 ASP D OD2 1 
ATOM   5095 N  N   . THR B 2 507 ? 93.291  128.854 103.717 1.00 100.32 ? 507 THR D N   1 
ATOM   5096 C  CA  . THR B 2 507 ? 92.023  128.148 103.592 1.00 100.32 ? 507 THR D CA  1 
ATOM   5097 C  C   . THR B 2 507 ? 91.460  127.833 104.974 1.00 100.32 ? 507 THR D C   1 
ATOM   5098 O  O   . THR B 2 507 ? 92.212  127.558 105.914 1.00 100.32 ? 507 THR D O   1 
ATOM   5099 C  CB  . THR B 2 507 ? 92.210  126.865 102.784 1.00 100.32 ? 507 THR D CB  1 
ATOM   5100 O  OG1 . THR B 2 507 ? 92.955  127.156 101.594 1.00 100.32 ? 507 THR D OG1 1 
ATOM   5101 C  CG2 . THR B 2 507 ? 90.863  126.282 102.386 1.00 100.32 ? 507 THR D CG2 1 
ATOM   5102 N  N   . ASP B 2 508 ? 90.131  127.880 105.094 1.00 107.90 ? 508 ASP D N   1 
ATOM   5103 C  CA  . ASP B 2 508 ? 89.487  127.680 106.389 1.00 107.90 ? 508 ASP D CA  1 
ATOM   5104 C  C   . ASP B 2 508 ? 89.736  126.280 106.938 1.00 107.90 ? 508 ASP D C   1 
ATOM   5105 O  O   . ASP B 2 508 ? 89.979  126.110 108.139 1.00 107.90 ? 508 ASP D O   1 
ATOM   5106 C  CB  . ASP B 2 508 ? 87.986  127.949 106.270 1.00 107.90 ? 508 ASP D CB  1 
ATOM   5107 C  CG  . ASP B 2 508 ? 87.372  127.293 105.048 1.00 107.90 ? 508 ASP D CG  1 
ATOM   5108 O  OD1 . ASP B 2 508 ? 88.073  126.506 104.377 1.00 107.90 ? 508 ASP D OD1 1 
ATOM   5109 O  OD2 . ASP B 2 508 ? 86.189  127.565 104.757 1.00 107.90 ? 508 ASP D OD2 1 
ATOM   5110 N  N   . VAL B 2 509 ? 89.679  125.263 106.072 1.00 105.76 ? 509 VAL D N   1 
ATOM   5111 C  CA  . VAL B 2 509 ? 89.846  123.884 106.526 1.00 105.76 ? 509 VAL D CA  1 
ATOM   5112 C  C   . VAL B 2 509 ? 91.232  123.673 107.119 1.00 105.76 ? 509 VAL D C   1 
ATOM   5113 O  O   . VAL B 2 509 ? 91.397  122.912 108.081 1.00 105.76 ? 509 VAL D O   1 
ATOM   5114 C  CB  . VAL B 2 509 ? 89.559  122.902 105.371 1.00 105.76 ? 509 VAL D CB  1 
ATOM   5115 C  CG1 . VAL B 2 509 ? 90.510  123.134 104.205 1.00 105.76 ? 509 VAL D CG1 1 
ATOM   5116 C  CG2 . VAL B 2 509 ? 89.644  121.462 105.858 1.00 105.76 ? 509 VAL D CG2 1 
ATOM   5117 N  N   . ILE B 2 510 ? 92.245  124.346 106.571 1.00 95.49  ? 510 ILE D N   1 
ATOM   5118 C  CA  . ILE B 2 510 ? 93.590  124.243 107.125 1.00 95.49  ? 510 ILE D CA  1 
ATOM   5119 C  C   . ILE B 2 510 ? 93.626  124.817 108.537 1.00 95.49  ? 510 ILE D C   1 
ATOM   5120 O  O   . ILE B 2 510 ? 94.253  124.249 109.438 1.00 95.49  ? 510 ILE D O   1 
ATOM   5121 C  CB  . ILE B 2 510 ? 94.604  124.936 106.198 1.00 95.49  ? 510 ILE D CB  1 
ATOM   5122 C  CG1 . ILE B 2 510 ? 95.099  123.946 105.144 1.00 95.49  ? 510 ILE D CG1 1 
ATOM   5123 C  CG2 . ILE B 2 510 ? 95.771  125.508 106.990 1.00 95.49  ? 510 ILE D CG2 1 
ATOM   5124 C  CD1 . ILE B 2 510 ? 96.115  122.966 105.670 1.00 95.49  ? 510 ILE D CD1 1 
ATOM   5125 N  N   . LEU B 2 511 ? 92.945  125.946 108.751 1.00 99.56  ? 511 LEU D N   1 
ATOM   5126 C  CA  . LEU B 2 511 ? 92.867  126.519 110.092 1.00 99.56  ? 511 LEU D CA  1 
ATOM   5127 C  C   . LEU B 2 511 ? 92.150  125.580 111.054 1.00 99.56  ? 511 LEU D C   1 
ATOM   5128 O  O   . LEU B 2 511 ? 92.582  125.405 112.201 1.00 99.56  ? 511 LEU D O   1 
ATOM   5129 C  CB  . LEU B 2 511 ? 92.163  127.876 110.045 1.00 99.56  ? 511 LEU D CB  1 
ATOM   5130 C  CG  . LEU B 2 511 ? 93.035  129.117 109.841 1.00 99.56  ? 511 LEU D CG  1 
ATOM   5131 C  CD1 . LEU B 2 511 ? 94.085  129.218 110.938 1.00 99.56  ? 511 LEU D CD1 1 
ATOM   5132 C  CD2 . LEU B 2 511 ? 93.686  129.122 108.466 1.00 99.56  ? 511 LEU D CD2 1 
ATOM   5133 N  N   . GLU B 2 512 ? 91.051  124.967 110.607 1.00 103.62 ? 512 GLU D N   1 
ATOM   5134 C  CA  . GLU B 2 512 ? 90.327  124.031 111.463 1.00 103.62 ? 512 GLU D CA  1 
ATOM   5135 C  C   . GLU B 2 512 ? 91.205  122.844 111.842 1.00 103.62 ? 512 GLU D C   1 
ATOM   5136 O  O   . GLU B 2 512 ? 91.207  122.401 112.996 1.00 103.62 ? 512 GLU D O   1 
ATOM   5137 C  CB  . GLU B 2 512 ? 89.049  123.555 110.771 1.00 103.62 ? 512 GLU D CB  1 
ATOM   5138 C  CG  . GLU B 2 512 ? 88.172  124.666 110.217 1.00 103.62 ? 512 GLU D CG  1 
ATOM   5139 C  CD  . GLU B 2 512 ? 88.036  125.838 111.168 1.00 103.62 ? 512 GLU D CD  1 
ATOM   5140 O  OE1 . GLU B 2 512 ? 87.221  125.748 112.111 1.00 103.62 ? 512 GLU D OE1 1 
ATOM   5141 O  OE2 . GLU B 2 512 ? 88.740  126.851 110.972 1.00 103.62 ? 512 GLU D OE2 1 
ATOM   5142 N  N   . ALA B 2 513 ? 91.956  122.312 110.876 1.00 101.49 ? 513 ALA D N   1 
ATOM   5143 C  CA  . ALA B 2 513 ? 92.858  121.202 111.167 1.00 101.49 ? 513 ALA D CA  1 
ATOM   5144 C  C   . ALA B 2 513 ? 93.969  121.623 112.122 1.00 101.49 ? 513 ALA D C   1 
ATOM   5145 O  O   . ALA B 2 513 ? 94.329  120.871 113.035 1.00 101.49 ? 513 ALA D O   1 
ATOM   5146 C  CB  . ALA B 2 513 ? 93.445  120.648 109.870 1.00 101.49 ? 513 ALA D CB  1 
ATOM   5147 N  N   . GLU B 2 514 ? 94.523  122.822 111.926 1.00 98.03  ? 514 GLU D N   1 
ATOM   5148 C  CA  . GLU B 2 514 ? 95.606  123.292 112.783 1.00 98.03  ? 514 GLU D CA  1 
ATOM   5149 C  C   . GLU B 2 514 ? 95.114  123.597 114.192 1.00 98.03  ? 514 GLU D C   1 
ATOM   5150 O  O   . GLU B 2 514 ? 95.907  123.593 115.141 1.00 98.03  ? 514 GLU D O   1 
ATOM   5151 C  CB  . GLU B 2 514 ? 96.259  124.527 112.157 1.00 98.03  ? 514 GLU D CB  1 
ATOM   5152 C  CG  . GLU B 2 514 ? 97.481  125.056 112.894 1.00 98.03  ? 514 GLU D CG  1 
ATOM   5153 C  CD  . GLU B 2 514 ? 97.140  126.169 113.866 1.00 98.03  ? 514 GLU D CD  1 
ATOM   5154 O  OE1 . GLU B 2 514 ? 95.964  126.587 113.902 1.00 98.03  ? 514 GLU D OE1 1 
ATOM   5155 O  OE2 . GLU B 2 514 ? 98.048  126.626 114.591 1.00 98.03  ? 514 GLU D OE2 1 
ATOM   5156 N  N   . ALA B 2 515 ? 93.813  123.857 114.350 1.00 101.19 ? 515 ALA D N   1 
ATOM   5157 C  CA  . ALA B 2 515 ? 93.275  124.160 115.673 1.00 101.19 ? 515 ALA D CA  1 
ATOM   5158 C  C   . ALA B 2 515 ? 93.462  122.998 116.641 1.00 101.19 ? 515 ALA D C   1 
ATOM   5159 O  O   . ALA B 2 515 ? 93.815  123.213 117.806 1.00 101.19 ? 515 ALA D O   1 
ATOM   5160 C  CB  . ALA B 2 515 ? 91.795  124.528 115.565 1.00 101.19 ? 515 ALA D CB  1 
ATOM   5161 N  N   . ASP B 2 516 ? 93.236  121.766 116.184 1.00 112.30 ? 516 ASP D N   1 
ATOM   5162 C  CA  . ASP B 2 516 ? 93.379  120.598 117.043 1.00 112.30 ? 516 ASP D CA  1 
ATOM   5163 C  C   . ASP B 2 516 ? 94.830  120.240 117.332 1.00 112.30 ? 516 ASP D C   1 
ATOM   5164 O  O   . ASP B 2 516 ? 95.091  119.528 118.308 1.00 112.30 ? 516 ASP D O   1 
ATOM   5165 C  CB  . ASP B 2 516 ? 92.677  119.391 116.414 1.00 112.30 ? 516 ASP D CB  1 
ATOM   5166 C  CG  . ASP B 2 516 ? 91.169  119.535 116.402 1.00 112.30 ? 516 ASP D CG  1 
ATOM   5167 O  OD1 . ASP B 2 516 ? 90.647  120.410 117.126 1.00 112.30 ? 516 ASP D OD1 1 
ATOM   5168 O  OD2 . ASP B 2 516 ? 90.505  118.773 115.669 1.00 112.30 ? 516 ASP D OD2 1 
ATOM   5169 N  N   . GLY B 2 517 ? 95.773  120.709 116.520 1.00 99.50  ? 517 GLY D N   1 
ATOM   5170 C  CA  . GLY B 2 517 ? 97.167  120.359 116.705 1.00 99.50  ? 517 GLY D CA  1 
ATOM   5171 C  C   . GLY B 2 517 ? 97.823  121.061 117.877 1.00 99.50  ? 517 GLY D C   1 
ATOM   5172 O  O   . GLY B 2 517 ? 97.928  122.291 117.893 1.00 99.50  ? 517 GLY D O   1 
ATOM   5173 N  N   . MET B 2 518 ? 98.266  120.288 118.865 1.00 86.22  ? 518 MET D N   1 
ATOM   5174 C  CA  . MET B 2 518 ? 98.979  120.857 119.997 1.00 86.22  ? 518 MET D CA  1 
ATOM   5175 C  C   . MET B 2 518 ? 100.357 121.347 119.564 1.00 86.22  ? 518 MET D C   1 
ATOM   5176 O  O   . MET B 2 518 ? 100.906 120.927 118.541 1.00 86.22  ? 518 MET D O   1 
ATOM   5177 C  CB  . MET B 2 518 ? 99.114  119.830 121.120 1.00 86.22  ? 518 MET D CB  1 
ATOM   5178 C  CG  . MET B 2 518 ? 98.275  120.140 122.348 1.00 86.22  ? 518 MET D CG  1 
ATOM   5179 S  SD  . MET B 2 518 ? 98.896  121.558 123.272 1.00 86.22  ? 518 MET D SD  1 
ATOM   5180 C  CE  . MET B 2 518 ? 97.607  121.756 124.499 1.00 86.22  ? 518 MET D CE  1 
ATOM   5181 N  N   . SER B 2 519 ? 100.921 122.248 120.364 1.00 87.88  ? 519 SER D N   1 
ATOM   5182 C  CA  . SER B 2 519 ? 102.197 122.864 120.041 1.00 87.88  ? 519 SER D CA  1 
ATOM   5183 C  C   . SER B 2 519 ? 103.095 122.856 121.269 1.00 87.88  ? 519 SER D C   1 
ATOM   5184 O  O   . SER B 2 519 ? 102.731 122.357 122.337 1.00 87.88  ? 519 SER D O   1 
ATOM   5185 C  CB  . SER B 2 519 ? 102.017 124.296 119.523 1.00 87.88  ? 519 SER D CB  1 
ATOM   5186 O  OG  . SER B 2 519 ? 103.238 124.813 119.021 1.00 87.88  ? 519 SER D OG  1 
ATOM   5187 N  N   . VAL B 2 520 ? 104.285 123.426 121.096 1.00 86.82  ? 520 VAL D N   1 
ATOM   5188 C  CA  . VAL B 2 520 ? 105.296 123.505 122.142 1.00 86.82  ? 520 VAL D CA  1 
ATOM   5189 C  C   . VAL B 2 520 ? 104.814 124.518 123.176 1.00 86.82  ? 520 VAL D C   1 
ATOM   5190 O  O   . VAL B 2 520 ? 103.838 125.238 122.932 1.00 86.82  ? 520 VAL D O   1 
ATOM   5191 C  CB  . VAL B 2 520 ? 106.659 123.874 121.525 1.00 86.82  ? 520 VAL D CB  1 
ATOM   5192 C  CG1 . VAL B 2 520 ? 107.783 123.893 122.560 1.00 86.82  ? 520 VAL D CG1 1 
ATOM   5193 C  CG2 . VAL B 2 520 ? 106.976 122.908 120.399 1.00 86.82  ? 520 VAL D CG2 1 
ATOM   5194 N  N   . MET B 2 521 ? 105.474 124.559 124.338 1.00 106.81 ? 521 MET D N   1 
ATOM   5195 C  CA  . MET B 2 521 ? 105.061 125.343 125.500 1.00 106.81 ? 521 MET D CA  1 
ATOM   5196 C  C   . MET B 2 521 ? 103.803 124.744 126.111 1.00 106.81 ? 521 MET D C   1 
ATOM   5197 O  O   . MET B 2 521 ? 103.637 123.519 126.110 1.00 106.81 ? 521 MET D O   1 
ATOM   5198 C  CB  . MET B 2 521 ? 104.841 126.819 125.150 1.00 106.81 ? 521 MET D CB  1 
ATOM   5199 C  CG  . MET B 2 521 ? 106.014 127.478 124.457 1.00 106.81 ? 521 MET D CG  1 
ATOM   5200 S  SD  . MET B 2 521 ? 107.062 128.341 125.638 1.00 106.81 ? 521 MET D SD  1 
ATOM   5201 C  CE  . MET B 2 521 ? 106.248 129.931 125.692 1.00 106.81 ? 521 MET D CE  1 
ATOM   5202 N  N   . ASP B 2 522 ? 102.915 125.594 126.630 1.00 107.42 ? 522 ASP D N   1 
ATOM   5203 C  CA  . ASP B 2 522 ? 101.774 125.144 127.424 1.00 107.42 ? 522 ASP D CA  1 
ATOM   5204 C  C   . ASP B 2 522 ? 102.230 124.246 128.569 1.00 107.42 ? 522 ASP D C   1 
ATOM   5205 O  O   . ASP B 2 522 ? 101.632 123.198 128.828 1.00 107.42 ? 522 ASP D O   1 
ATOM   5206 C  CB  . ASP B 2 522 ? 100.733 124.427 126.558 1.00 107.42 ? 522 ASP D CB  1 
ATOM   5207 C  CG  . ASP B 2 522 ? 100.316 125.245 125.353 1.00 107.42 ? 522 ASP D CG  1 
ATOM   5208 O  OD1 . ASP B 2 522 ? 100.894 126.331 125.141 1.00 107.42 ? 522 ASP D OD1 1 
ATOM   5209 O  OD2 . ASP B 2 522 ? 99.412  124.800 124.616 1.00 107.42 ? 522 ASP D OD2 1 
ATOM   5210 N  N   . ALA B 2 523 ? 103.304 124.656 129.249 1.00 97.52  ? 523 ALA D N   1 
ATOM   5211 C  CA  . ALA B 2 523 ? 103.955 123.786 130.223 1.00 97.52  ? 523 ALA D CA  1 
ATOM   5212 C  C   . ALA B 2 523 ? 103.017 123.418 131.364 1.00 97.52  ? 523 ALA D C   1 
ATOM   5213 O  O   . ALA B 2 523 ? 102.985 122.261 131.799 1.00 97.52  ? 523 ALA D O   1 
ATOM   5214 C  CB  . ALA B 2 523 ? 105.219 124.457 130.762 1.00 97.52  ? 523 ALA D CB  1 
ATOM   5215 N  N   . LEU B 2 524 ? 102.242 124.385 131.862 1.00 98.06  ? 524 LEU D N   1 
ATOM   5216 C  CA  . LEU B 2 524 ? 101.336 124.101 132.968 1.00 98.06  ? 524 LEU D CA  1 
ATOM   5217 C  C   . LEU B 2 524 ? 100.284 123.063 132.604 1.00 98.06  ? 524 LEU D C   1 
ATOM   5218 O  O   . LEU B 2 524 ? 100.010 122.170 133.412 1.00 98.06  ? 524 LEU D O   1 
ATOM   5219 C  CB  . LEU B 2 524 ? 100.655 125.384 133.442 1.00 98.06  ? 524 LEU D CB  1 
ATOM   5220 C  CG  . LEU B 2 524 ? 99.806  125.226 134.704 1.00 98.06  ? 524 LEU D CG  1 
ATOM   5221 C  CD1 . LEU B 2 524 ? 100.587 124.507 135.795 1.00 98.06  ? 524 LEU D CD1 1 
ATOM   5222 C  CD2 . LEU B 2 524 ? 99.330  126.574 135.193 1.00 98.06  ? 524 LEU D CD2 1 
ATOM   5223 N  N   . TYR B 2 525 ? 99.691  123.158 131.414 1.00 104.59 ? 525 TYR D N   1 
ATOM   5224 C  CA  . TYR B 2 525 ? 98.754  122.130 130.978 1.00 104.59 ? 525 TYR D CA  1 
ATOM   5225 C  C   . TYR B 2 525 ? 99.477  120.827 130.660 1.00 104.59 ? 525 TYR D C   1 
ATOM   5226 O  O   . TYR B 2 525 ? 98.937  119.738 130.881 1.00 104.59 ? 525 TYR D O   1 
ATOM   5227 C  CB  . TYR B 2 525 ? 97.960  122.615 129.763 1.00 104.59 ? 525 TYR D CB  1 
ATOM   5228 C  CG  . TYR B 2 525 ? 96.785  121.729 129.411 1.00 104.59 ? 525 TYR D CG  1 
ATOM   5229 C  CD1 . TYR B 2 525 ? 96.931  120.663 128.532 1.00 104.59 ? 525 TYR D CD1 1 
ATOM   5230 C  CD2 . TYR B 2 525 ? 95.531  121.952 129.965 1.00 104.59 ? 525 TYR D CD2 1 
ATOM   5231 C  CE1 . TYR B 2 525 ? 95.861  119.849 128.210 1.00 104.59 ? 525 TYR D CE1 1 
ATOM   5232 C  CE2 . TYR B 2 525 ? 94.455  121.143 129.650 1.00 104.59 ? 525 TYR D CE2 1 
ATOM   5233 C  CZ  . TYR B 2 525 ? 94.626  120.094 128.772 1.00 104.59 ? 525 TYR D CZ  1 
ATOM   5234 O  OH  . TYR B 2 525 ? 93.558  119.287 128.455 1.00 104.59 ? 525 TYR D OH  1 
ATOM   5235 N  N   . ALA B 2 526 ? 100.702 120.921 130.139 1.00 97.07  ? 526 ALA D N   1 
ATOM   5236 C  CA  . ALA B 2 526 ? 101.448 119.719 129.783 1.00 97.07  ? 526 ALA D CA  1 
ATOM   5237 C  C   . ALA B 2 526 ? 102.039 119.053 131.020 1.00 97.07  ? 526 ALA D C   1 
ATOM   5238 O  O   . ALA B 2 526 ? 101.669 117.927 131.371 1.00 97.07  ? 526 ALA D O   1 
ATOM   5239 C  CB  . ALA B 2 526 ? 102.548 120.064 128.776 1.00 97.07  ? 526 ALA D CB  1 
ATOM   5240 N  N   . ASN B 2 527 ? 102.952 119.743 131.706 1.00 78.27  ? 527 ASN D N   1 
ATOM   5241 C  CA  . ASN B 2 527 ? 103.620 119.175 132.880 1.00 78.27  ? 527 ASN D CA  1 
ATOM   5242 C  C   . ASN B 2 527 ? 103.871 120.309 133.876 1.00 78.27  ? 527 ASN D C   1 
ATOM   5243 O  O   . ASN B 2 527 ? 104.796 121.107 133.705 1.00 78.27  ? 527 ASN D O   1 
ATOM   5244 C  CB  . ASN B 2 527 ? 104.918 118.472 132.506 1.00 78.27  ? 527 ASN D CB  1 
ATOM   5245 C  CG  . ASN B 2 527 ? 104.690 117.124 131.850 1.00 78.27  ? 527 ASN D CG  1 
ATOM   5246 O  OD1 . ASN B 2 527 ? 104.202 117.040 130.725 1.00 78.27  ? 527 ASN D OD1 1 
ATOM   5247 N  ND2 . ASN B 2 527 ? 105.044 116.058 132.558 1.00 78.27  ? 527 ASN D ND2 1 
ATOM   5248 N  N   . LYS B 2 528 ? 103.036 120.368 134.915 1.00 71.89  ? 528 LYS D N   1 
ATOM   5249 C  CA  . LYS B 2 528 ? 103.329 121.251 136.038 1.00 71.89  ? 528 LYS D CA  1 
ATOM   5250 C  C   . LYS B 2 528 ? 104.613 120.826 136.737 1.00 71.89  ? 528 LYS D C   1 
ATOM   5251 O  O   . LYS B 2 528 ? 105.322 121.663 137.316 1.00 71.89  ? 528 LYS D O   1 
ATOM   5252 C  CB  . LYS B 2 528 ? 102.155 121.257 137.019 1.00 71.89  ? 528 LYS D CB  1 
ATOM   5253 C  CG  . LYS B 2 528 ? 102.335 122.173 138.217 1.00 71.89  ? 528 LYS D CG  1 
ATOM   5254 C  CD  . LYS B 2 528 ? 101.075 122.225 139.062 1.00 71.89  ? 528 LYS D CD  1 
ATOM   5255 C  CE  . LYS B 2 528 ? 100.635 120.830 139.477 1.00 71.89  ? 528 LYS D CE  1 
ATOM   5256 N  NZ  . LYS B 2 528 ? 101.602 120.200 140.418 1.00 71.89  ? 528 LYS D NZ  1 
ATOM   5257 N  N   . ALA B 2 529 ? 104.932 119.531 136.681 1.00 66.46  ? 529 ALA D N   1 
ATOM   5258 C  CA  . ALA B 2 529 ? 106.181 119.046 137.252 1.00 66.46  ? 529 ALA D CA  1 
ATOM   5259 C  C   . ALA B 2 529 ? 107.387 119.692 136.588 1.00 66.46  ? 529 ALA D C   1 
ATOM   5260 O  O   . ALA B 2 529 ? 108.432 119.844 137.224 1.00 66.46  ? 529 ALA D O   1 
ATOM   5261 C  CB  . ALA B 2 529 ? 106.260 117.524 137.134 1.00 66.46  ? 529 ALA D CB  1 
ATOM   5262 N  N   . SER B 2 530 ? 107.265 120.086 135.318 1.00 65.28  ? 530 SER D N   1 
ATOM   5263 C  CA  . SER B 2 530 ? 108.356 120.809 134.670 1.00 65.28  ? 530 SER D CA  1 
ATOM   5264 C  C   . SER B 2 530 ? 108.595 122.159 135.336 1.00 65.28  ? 530 SER D C   1 
ATOM   5265 O  O   . SER B 2 530 ? 109.745 122.534 135.599 1.00 65.28  ? 530 SER D O   1 
ATOM   5266 C  CB  . SER B 2 530 ? 108.060 120.988 133.182 1.00 65.28  ? 530 SER D CB  1 
ATOM   5267 O  OG  . SER B 2 530 ? 107.941 119.735 132.533 1.00 65.28  ? 530 SER D OG  1 
ATOM   5268 N  N   . LEU B 2 531 ? 107.521 122.901 135.620 1.00 61.85  ? 531 LEU D N   1 
ATOM   5269 C  CA  . LEU B 2 531 ? 107.667 124.172 136.321 1.00 61.85  ? 531 LEU D CA  1 
ATOM   5270 C  C   . LEU B 2 531 ? 108.233 123.964 137.718 1.00 61.85  ? 531 LEU D C   1 
ATOM   5271 O  O   . LEU B 2 531 ? 109.089 124.735 138.172 1.00 61.85  ? 531 LEU D O   1 
ATOM   5272 C  CB  . LEU B 2 531 ? 106.321 124.892 136.390 1.00 61.85  ? 531 LEU D CB  1 
ATOM   5273 C  CG  . LEU B 2 531 ? 105.725 125.356 135.062 1.00 61.85  ? 531 LEU D CG  1 
ATOM   5274 C  CD1 . LEU B 2 531 ? 104.414 126.088 135.293 1.00 61.85  ? 531 LEU D CD1 1 
ATOM   5275 C  CD2 . LEU B 2 531 ? 106.708 126.239 134.313 1.00 61.85  ? 531 LEU D CD2 1 
ATOM   5276 N  N   . VAL B 2 532 ? 107.765 122.925 138.415 1.00 59.31  ? 532 VAL D N   1 
ATOM   5277 C  CA  . VAL B 2 532 ? 108.297 122.628 139.742 1.00 59.31  ? 532 VAL D CA  1 
ATOM   5278 C  C   . VAL B 2 532 ? 109.785 122.315 139.668 1.00 59.31  ? 532 VAL D C   1 
ATOM   5279 O  O   . VAL B 2 532 ? 110.568 122.781 140.504 1.00 59.31  ? 532 VAL D O   1 
ATOM   5280 C  CB  . VAL B 2 532 ? 107.509 121.474 140.391 1.00 59.31  ? 532 VAL D CB  1 
ATOM   5281 C  CG1 . VAL B 2 532 ? 108.082 121.145 141.759 1.00 59.31  ? 532 VAL D CG1 1 
ATOM   5282 C  CG2 . VAL B 2 532 ? 106.038 121.835 140.502 1.00 59.31  ? 532 VAL D CG2 1 
ATOM   5283 N  N   . ALA B 2 533 ? 110.201 121.531 138.672 1.00 57.44  ? 533 ALA D N   1 
ATOM   5284 C  CA  . ALA B 2 533 ? 111.613 121.203 138.513 1.00 57.44  ? 533 ALA D CA  1 
ATOM   5285 C  C   . ALA B 2 533 ? 112.440 122.450 138.229 1.00 57.44  ? 533 ALA D C   1 
ATOM   5286 O  O   . ALA B 2 533 ? 113.518 122.630 138.803 1.00 57.44  ? 533 ALA D O   1 
ATOM   5287 C  CB  . ALA B 2 533 ? 111.789 120.171 137.400 1.00 57.44  ? 533 ALA D CB  1 
ATOM   5288 N  N   . ILE B 2 534 ? 111.945 123.329 137.354 1.00 57.11  ? 534 ILE D N   1 
ATOM   5289 C  CA  . ILE B 2 534 ? 112.666 124.568 137.056 1.00 57.11  ? 534 ILE D CA  1 
ATOM   5290 C  C   . ILE B 2 534 ? 112.843 125.392 138.325 1.00 57.11  ? 534 ILE D C   1 
ATOM   5291 O  O   . ILE B 2 534 ? 113.950 125.835 138.659 1.00 57.11  ? 534 ILE D O   1 
ATOM   5292 C  CB  . ILE B 2 534 ? 111.934 125.380 135.973 1.00 57.11  ? 534 ILE D CB  1 
ATOM   5293 C  CG1 . ILE B 2 534 ? 111.976 124.663 134.627 1.00 57.11  ? 534 ILE D CG1 1 
ATOM   5294 C  CG2 . ILE B 2 534 ? 112.544 126.763 135.843 1.00 57.11  ? 534 ILE D CG2 1 
ATOM   5295 C  CD1 . ILE B 2 534 ? 111.240 125.394 133.529 1.00 57.11  ? 534 ILE D CD1 1 
ATOM   5296 N  N   . PHE B 2 535 ? 111.754 125.586 139.063 1.00 67.77  ? 535 PHE D N   1 
ATOM   5297 C  CA  . PHE B 2 535 ? 111.752 126.499 140.202 1.00 67.77  ? 535 PHE D CA  1 
ATOM   5298 C  C   . PHE B 2 535 ? 112.311 125.863 141.467 1.00 67.77  ? 535 PHE D C   1 
ATOM   5299 O  O   . PHE B 2 535 ? 112.431 126.520 142.502 1.00 67.77  ? 535 PHE D O   1 
ATOM   5300 C  CB  . PHE B 2 535 ? 110.330 127.011 140.411 1.00 67.77  ? 535 PHE D CB  1 
ATOM   5301 C  CG  . PHE B 2 535 ? 109.920 128.060 139.413 1.00 67.77  ? 535 PHE D CG  1 
ATOM   5302 C  CD1 . PHE B 2 535 ? 110.801 128.471 138.425 1.00 67.77  ? 535 PHE D CD1 1 
ATOM   5303 C  CD2 . PHE B 2 535 ? 108.651 128.610 139.435 1.00 67.77  ? 535 PHE D CD2 1 
ATOM   5304 C  CE1 . PHE B 2 535 ? 110.435 129.423 137.497 1.00 67.77  ? 535 PHE D CE1 1 
ATOM   5305 C  CE2 . PHE B 2 535 ? 108.280 129.562 138.502 1.00 67.77  ? 535 PHE D CE2 1 
ATOM   5306 C  CZ  . PHE B 2 535 ? 109.173 129.969 137.536 1.00 67.77  ? 535 PHE D CZ  1 
ATOM   5307 N  N   . ASN B 2 536 ? 112.652 124.577 141.402 1.00 63.63  ? 536 ASN D N   1 
ATOM   5308 C  CA  . ASN B 2 536 ? 113.429 123.942 142.457 1.00 63.63  ? 536 ASN D CA  1 
ATOM   5309 C  C   . ASN B 2 536 ? 114.905 123.939 142.076 1.00 63.63  ? 536 ASN D C   1 
ATOM   5310 O  O   . ASN B 2 536 ? 115.779 123.966 142.948 1.00 63.63  ? 536 ASN D O   1 
ATOM   5311 C  CB  . ASN B 2 536 ? 112.928 122.518 142.710 1.00 63.63  ? 536 ASN D CB  1 
ATOM   5312 C  CG  . ASN B 2 536 ? 113.744 121.787 143.758 1.00 63.63  ? 536 ASN D CG  1 
ATOM   5313 O  OD1 . ASN B 2 536 ? 114.832 121.282 143.478 1.00 63.63  ? 536 ASN D OD1 1 
ATOM   5314 N  ND2 . ASN B 2 536 ? 113.219 121.724 144.976 1.00 63.63  ? 536 ASN D ND2 1 
ATOM   5315 N  N   . ILE B 2 537 ? 115.190 123.903 140.772 1.00 58.68  ? 537 ILE D N   1 
ATOM   5316 C  CA  . ILE B 2 537 ? 116.573 123.951 140.308 1.00 58.68  ? 537 ILE D CA  1 
ATOM   5317 C  C   . ILE B 2 537 ? 117.164 125.336 140.532 1.00 58.68  ? 537 ILE D C   1 
ATOM   5318 O  O   . ILE B 2 537 ? 118.309 125.473 140.979 1.00 58.68  ? 537 ILE D O   1 
ATOM   5319 C  CB  . ILE B 2 537 ? 116.654 123.529 138.829 1.00 58.68  ? 537 ILE D CB  1 
ATOM   5320 C  CG1 . ILE B 2 537 ? 116.666 122.004 138.711 1.00 58.68  ? 537 ILE D CG1 1 
ATOM   5321 C  CG2 . ILE B 2 537 ? 117.886 124.118 138.163 1.00 58.68  ? 537 ILE D CG2 1 
ATOM   5322 C  CD1 . ILE B 2 537 ? 116.261 121.498 137.349 1.00 58.68  ? 537 ILE D CD1 1 
ATOM   5323 N  N   . ILE B 2 538 ? 116.390 126.389 140.241 1.00 65.98  ? 538 ILE D N   1 
ATOM   5324 C  CA  . ILE B 2 538 ? 116.899 127.750 140.418 1.00 65.98  ? 538 ILE D CA  1 
ATOM   5325 C  C   . ILE B 2 538 ? 117.022 128.152 141.878 1.00 65.98  ? 538 ILE D C   1 
ATOM   5326 O  O   . ILE B 2 538 ? 117.434 129.284 142.163 1.00 65.98  ? 538 ILE D O   1 
ATOM   5327 C  CB  . ILE B 2 538 ? 116.025 128.796 139.698 1.00 65.98  ? 538 ILE D CB  1 
ATOM   5328 C  CG1 . ILE B 2 538 ? 114.710 129.011 140.449 1.00 65.98  ? 538 ILE D CG1 1 
ATOM   5329 C  CG2 . ILE B 2 538 ? 115.781 128.392 138.253 1.00 65.98  ? 538 ILE D CG2 1 
ATOM   5330 C  CD1 . ILE B 2 538 ? 113.935 130.224 139.983 1.00 65.98  ? 538 ILE D CD1 1 
ATOM   5331 N  N   . ASP B 2 539 ? 116.683 127.266 142.813 1.00 71.21  ? 539 ASP D N   1 
ATOM   5332 C  CA  . ASP B 2 539 ? 116.804 127.568 144.236 1.00 71.21  ? 539 ASP D CA  1 
ATOM   5333 C  C   . ASP B 2 539 ? 118.274 127.605 144.632 1.00 71.21  ? 539 ASP D C   1 
ATOM   5334 O  O   . ASP B 2 539 ? 118.919 126.559 144.756 1.00 71.21  ? 539 ASP D O   1 
ATOM   5335 C  CB  . ASP B 2 539 ? 116.051 126.530 145.064 1.00 71.21  ? 539 ASP D CB  1 
ATOM   5336 C  CG  . ASP B 2 539 ? 114.581 126.858 145.216 1.00 71.21  ? 539 ASP D CG  1 
ATOM   5337 O  OD1 . ASP B 2 539 ? 114.147 127.904 144.692 1.00 71.21  ? 539 ASP D OD1 1 
ATOM   5338 O  OD2 . ASP B 2 539 ? 113.859 126.071 145.864 1.00 71.21  ? 539 ASP D OD2 1 
ATOM   5339 N  N   . ALA B 2 540 ? 118.810 128.811 144.831 1.00 98.62  ? 540 ALA D N   1 
ATOM   5340 C  CA  . ALA B 2 540 ? 120.162 128.941 145.360 1.00 98.62  ? 540 ALA D CA  1 
ATOM   5341 C  C   . ALA B 2 540 ? 120.257 128.431 146.791 1.00 98.62  ? 540 ALA D C   1 
ATOM   5342 O  O   . ALA B 2 540 ? 121.272 127.836 147.168 1.00 98.62  ? 540 ALA D O   1 
ATOM   5343 C  CB  . ALA B 2 540 ? 120.621 130.398 145.290 1.00 98.62  ? 540 ALA D CB  1 
ATOM   5344 N  N   . ASP B 2 541 ? 119.220 128.654 147.593 1.00 103.57 ? 541 ASP D N   1 
ATOM   5345 C  CA  . ASP B 2 541 ? 119.138 128.143 148.954 1.00 103.57 ? 541 ASP D CA  1 
ATOM   5346 C  C   . ASP B 2 541 ? 118.039 127.091 149.037 1.00 103.57 ? 541 ASP D C   1 
ATOM   5347 O  O   . ASP B 2 541 ? 117.188 127.005 148.145 1.00 103.57 ? 541 ASP D O   1 
ATOM   5348 C  CB  . ASP B 2 541 ? 118.908 129.285 149.954 1.00 103.57 ? 541 ASP D CB  1 
ATOM   5349 C  CG  . ASP B 2 541 ? 117.444 129.702 150.077 1.00 103.57 ? 541 ASP D CG  1 
ATOM   5350 O  OD1 . ASP B 2 541 ? 116.654 129.504 149.129 1.00 103.57 ? 541 ASP D OD1 1 
ATOM   5351 O  OD2 . ASP B 2 541 ? 117.083 130.243 151.142 1.00 103.57 ? 541 ASP D OD2 1 
ATOM   5352 N  N   . ASN B 2 542 ? 118.070 126.283 150.096 1.00 108.25 ? 542 ASN D N   1 
ATOM   5353 C  CA  . ASN B 2 542 ? 117.101 125.204 150.239 1.00 108.25 ? 542 ASN D CA  1 
ATOM   5354 C  C   . ASN B 2 542 ? 115.821 125.636 150.942 1.00 108.25 ? 542 ASN D C   1 
ATOM   5355 O  O   . ASN B 2 542 ? 114.906 124.815 151.071 1.00 108.25 ? 542 ASN D O   1 
ATOM   5356 C  CB  . ASN B 2 542 ? 117.735 124.031 150.988 1.00 108.25 ? 542 ASN D CB  1 
ATOM   5357 C  CG  . ASN B 2 542 ? 118.873 123.396 150.214 1.00 108.25 ? 542 ASN D CG  1 
ATOM   5358 O  OD1 . ASN B 2 542 ? 120.031 123.789 150.357 1.00 108.25 ? 542 ASN D OD1 1 
ATOM   5359 N  ND2 . ASN B 2 542 ? 118.549 122.411 149.385 1.00 108.25 ? 542 ASN D ND2 1 
ATOM   5360 N  N   . SER B 2 543 ? 115.728 126.886 151.395 1.00 106.28 ? 543 SER D N   1 
ATOM   5361 C  CA  . SER B 2 543 ? 114.516 127.360 152.055 1.00 106.28 ? 543 SER D CA  1 
ATOM   5362 C  C   . SER B 2 543 ? 113.351 127.551 151.094 1.00 106.28 ? 543 SER D C   1 
ATOM   5363 O  O   . SER B 2 543 ? 112.220 127.742 151.555 1.00 106.28 ? 543 SER D O   1 
ATOM   5364 C  CB  . SER B 2 543 ? 114.797 128.671 152.793 1.00 106.28 ? 543 SER D CB  1 
ATOM   5365 O  OG  . SER B 2 543 ? 115.817 128.503 153.762 1.00 106.28 ? 543 SER D OG  1 
ATOM   5366 N  N   . GLY B 2 544 ? 113.590 127.506 149.785 1.00 99.78  ? 544 GLY D N   1 
ATOM   5367 C  CA  . GLY B 2 544 ? 112.515 127.649 148.826 1.00 99.78  ? 544 GLY D CA  1 
ATOM   5368 C  C   . GLY B 2 544 ? 112.199 129.068 148.417 1.00 99.78  ? 544 GLY D C   1 
ATOM   5369 O  O   . GLY B 2 544 ? 111.162 129.301 147.789 1.00 99.78  ? 544 GLY D O   1 
ATOM   5370 N  N   . GLU B 2 545 ? 113.060 130.025 148.747 1.00 100.89 ? 545 GLU D N   1 
ATOM   5371 C  CA  . GLU B 2 545 ? 112.850 131.424 148.406 1.00 100.89 ? 545 GLU D CA  1 
ATOM   5372 C  C   . GLU B 2 545 ? 113.782 131.827 147.271 1.00 100.89 ? 545 GLU D C   1 
ATOM   5373 O  O   . GLU B 2 545 ? 114.948 131.422 147.239 1.00 100.89 ? 545 GLU D O   1 
ATOM   5374 C  CB  . GLU B 2 545 ? 113.079 132.327 149.621 1.00 100.89 ? 545 GLU D CB  1 
ATOM   5375 C  CG  . GLU B 2 545 ? 112.173 132.016 150.802 1.00 100.89 ? 545 GLU D CG  1 
ATOM   5376 C  CD  . GLU B 2 545 ? 112.236 133.078 151.882 1.00 100.89 ? 545 GLU D CD  1 
ATOM   5377 O  OE1 . GLU B 2 545 ? 112.825 134.150 151.629 1.00 100.89 ? 545 GLU D OE1 1 
ATOM   5378 O  OE2 . GLU B 2 545 ? 111.694 132.841 152.982 1.00 100.89 ? 545 GLU D OE2 1 
ATOM   5379 N  N   . ILE B 2 546 ? 113.260 132.625 146.341 1.00 99.89  ? 546 ILE D N   1 
ATOM   5380 C  CA  . ILE B 2 546 ? 114.006 133.059 145.169 1.00 99.89  ? 546 ILE D CA  1 
ATOM   5381 C  C   . ILE B 2 546 ? 113.970 134.578 145.086 1.00 99.89  ? 546 ILE D C   1 
ATOM   5382 O  O   . ILE B 2 546 ? 113.101 135.233 145.670 1.00 99.89  ? 546 ILE D O   1 
ATOM   5383 C  CB  . ILE B 2 546 ? 113.454 132.440 143.865 1.00 99.89  ? 546 ILE D CB  1 
ATOM   5384 C  CG1 . ILE B 2 546 ? 112.042 132.958 143.585 1.00 99.89  ? 546 ILE D CG1 1 
ATOM   5385 C  CG2 . ILE B 2 546 ? 113.465 130.925 143.944 1.00 99.89  ? 546 ILE D CG2 1 
ATOM   5386 C  CD1 . ILE B 2 546 ? 111.465 132.473 142.275 1.00 99.89  ? 546 ILE D CD1 1 
ATOM   5387 N  N   . THR B 2 547 ? 114.929 135.134 144.353 1.00 103.19 ? 547 THR D N   1 
ATOM   5388 C  CA  . THR B 2 547 ? 115.013 136.574 144.161 1.00 103.19 ? 547 THR D CA  1 
ATOM   5389 C  C   . THR B 2 547 ? 114.841 136.927 142.687 1.00 103.19 ? 547 THR D C   1 
ATOM   5390 O  O   . THR B 2 547 ? 115.152 136.132 141.795 1.00 103.19 ? 547 THR D O   1 
ATOM   5391 C  CB  . THR B 2 547 ? 116.347 137.107 144.686 1.00 103.19 ? 547 THR D CB  1 
ATOM   5392 O  OG1 . THR B 2 547 ? 117.363 136.916 143.694 1.00 103.19 ? 547 THR D OG1 1 
ATOM   5393 C  CG2 . THR B 2 547 ? 116.750 136.387 145.965 1.00 103.19 ? 547 THR D CG2 1 
ATOM   5394 N  N   . LEU B 2 548 ? 114.337 138.140 142.439 1.00 105.97 ? 548 LEU D N   1 
ATOM   5395 C  CA  . LEU B 2 548 ? 113.910 138.524 141.096 1.00 105.97 ? 548 LEU D CA  1 
ATOM   5396 C  C   . LEU B 2 548 ? 115.048 138.547 140.082 1.00 105.97 ? 548 LEU D C   1 
ATOM   5397 O  O   . LEU B 2 548 ? 114.799 138.311 138.894 1.00 105.97 ? 548 LEU D O   1 
ATOM   5398 C  CB  . LEU B 2 548 ? 113.220 139.890 141.127 1.00 105.97 ? 548 LEU D CB  1 
ATOM   5399 C  CG  . LEU B 2 548 ? 111.697 139.917 141.297 1.00 105.97 ? 548 LEU D CG  1 
ATOM   5400 C  CD1 . LEU B 2 548 ? 111.018 139.568 139.982 1.00 105.97 ? 548 LEU D CD1 1 
ATOM   5401 C  CD2 . LEU B 2 548 ? 111.226 138.982 142.398 1.00 105.97 ? 548 LEU D CD2 1 
ATOM   5402 N  N   . ASP B 2 549 ? 116.280 138.840 140.503 1.00 104.13 ? 549 ASP D N   1 
ATOM   5403 C  CA  . ASP B 2 549 ? 117.392 138.793 139.557 1.00 104.13 ? 549 ASP D CA  1 
ATOM   5404 C  C   . ASP B 2 549 ? 117.599 137.379 139.028 1.00 104.13 ? 549 ASP D C   1 
ATOM   5405 O  O   . ASP B 2 549 ? 117.835 137.186 137.829 1.00 104.13 ? 549 ASP D O   1 
ATOM   5406 C  CB  . ASP B 2 549 ? 118.670 139.326 140.206 1.00 104.13 ? 549 ASP D CB  1 
ATOM   5407 C  CG  . ASP B 2 549 ? 118.794 138.926 141.656 1.00 104.13 ? 549 ASP D CG  1 
ATOM   5408 O  OD1 . ASP B 2 549 ? 119.826 139.248 142.282 1.00 104.13 ? 549 ASP D OD1 1 
ATOM   5409 O  OD2 . ASP B 2 549 ? 117.853 138.293 142.171 1.00 104.13 ? 549 ASP D OD2 1 
ATOM   5410 N  N   . GLU B 2 550 ? 117.504 136.377 139.905 1.00 92.67  ? 550 GLU D N   1 
ATOM   5411 C  CA  . GLU B 2 550 ? 117.498 134.993 139.442 1.00 92.67  ? 550 GLU D CA  1 
ATOM   5412 C  C   . GLU B 2 550 ? 116.277 134.714 138.576 1.00 92.67  ? 550 GLU D C   1 
ATOM   5413 O  O   . GLU B 2 550 ? 116.367 133.984 137.583 1.00 92.67  ? 550 GLU D O   1 
ATOM   5414 C  CB  . GLU B 2 550 ? 117.541 134.037 140.633 1.00 92.67  ? 550 GLU D CB  1 
ATOM   5415 C  CG  . GLU B 2 550 ? 118.876 134.000 141.352 1.00 92.67  ? 550 GLU D CG  1 
ATOM   5416 C  CD  . GLU B 2 550 ? 118.797 133.280 142.682 1.00 92.67  ? 550 GLU D CD  1 
ATOM   5417 O  OE1 . GLU B 2 550 ? 117.782 133.447 143.390 1.00 92.67  ? 550 GLU D OE1 1 
ATOM   5418 O  OE2 . GLU B 2 550 ? 119.749 132.547 143.018 1.00 92.67  ? 550 GLU D OE2 1 
ATOM   5419 N  N   . PHE B 2 551 ? 115.127 135.283 138.943 1.00 93.31  ? 551 PHE D N   1 
ATOM   5420 C  CA  . PHE B 2 551 ? 113.926 135.145 138.126 1.00 93.31  ? 551 PHE D CA  1 
ATOM   5421 C  C   . PHE B 2 551 ? 114.146 135.744 136.741 1.00 93.31  ? 551 PHE D C   1 
ATOM   5422 O  O   . PHE B 2 551 ? 113.791 135.137 135.721 1.00 93.31  ? 551 PHE D O   1 
ATOM   5423 C  CB  . PHE B 2 551 ? 112.751 135.818 138.839 1.00 93.31  ? 551 PHE D CB  1 
ATOM   5424 C  CG  . PHE B 2 551 ? 111.405 135.235 138.508 1.00 93.31  ? 551 PHE D CG  1 
ATOM   5425 C  CD1 . PHE B 2 551 ? 110.985 135.096 137.197 1.00 93.31  ? 551 PHE D CD1 1 
ATOM   5426 C  CD2 . PHE B 2 551 ? 110.553 134.830 139.522 1.00 93.31  ? 551 PHE D CD2 1 
ATOM   5427 C  CE1 . PHE B 2 551 ? 109.742 134.564 136.907 1.00 93.31  ? 551 PHE D CE1 1 
ATOM   5428 C  CE2 . PHE B 2 551 ? 109.313 134.296 139.236 1.00 93.31  ? 551 PHE D CE2 1 
ATOM   5429 C  CZ  . PHE B 2 551 ? 108.907 134.162 137.927 1.00 93.31  ? 551 PHE D CZ  1 
ATOM   5430 N  N   . GLU B 2 552 ? 114.745 136.937 136.687 1.00 99.75  ? 552 GLU D N   1 
ATOM   5431 C  CA  . GLU B 2 552 ? 115.047 137.562 135.404 1.00 99.75  ? 552 GLU D CA  1 
ATOM   5432 C  C   . GLU B 2 552 ? 116.008 136.714 134.583 1.00 99.75  ? 552 GLU D C   1 
ATOM   5433 O  O   . GLU B 2 552 ? 115.830 136.568 133.370 1.00 99.75  ? 552 GLU D O   1 
ATOM   5434 C  CB  . GLU B 2 552 ? 115.621 138.962 135.617 1.00 99.75  ? 552 GLU D CB  1 
ATOM   5435 C  CG  . GLU B 2 552 ? 114.588 140.071 135.558 1.00 99.75  ? 552 GLU D CG  1 
ATOM   5436 C  CD  . GLU B 2 552 ? 114.318 140.517 134.132 1.00 99.75  ? 552 GLU D CD  1 
ATOM   5437 O  OE1 . GLU B 2 552 ? 113.254 141.116 133.879 1.00 99.75  ? 552 GLU D OE1 1 
ATOM   5438 O  OE2 . GLU B 2 552 ? 115.177 140.265 133.261 1.00 99.75  ? 552 GLU D OE2 1 
ATOM   5439 N  N   . THR B 2 553 ? 117.038 136.156 135.222 1.00 89.65  ? 553 THR D N   1 
ATOM   5440 C  CA  . THR B 2 553 ? 117.971 135.298 134.497 1.00 89.65  ? 553 THR D CA  1 
ATOM   5441 C  C   . THR B 2 553 ? 117.268 134.061 133.951 1.00 89.65  ? 553 THR D C   1 
ATOM   5442 O  O   . THR B 2 553 ? 117.530 133.635 132.818 1.00 89.65  ? 553 THR D O   1 
ATOM   5443 C  CB  . THR B 2 553 ? 119.133 134.899 135.407 1.00 89.65  ? 553 THR D CB  1 
ATOM   5444 O  OG1 . THR B 2 553 ? 119.700 136.073 136.002 1.00 89.65  ? 553 THR D OG1 1 
ATOM   5445 C  CG2 . THR B 2 553 ? 120.208 134.174 134.612 1.00 89.65  ? 553 THR D CG2 1 
ATOM   5446 N  N   . ALA B 2 554 ? 116.370 133.472 134.744 1.00 84.05  ? 554 ALA D N   1 
ATOM   5447 C  CA  . ALA B 2 554 ? 115.643 132.291 134.293 1.00 84.05  ? 554 ALA D CA  1 
ATOM   5448 C  C   . ALA B 2 554 ? 114.767 132.604 133.087 1.00 84.05  ? 554 ALA D C   1 
ATOM   5449 O  O   . ALA B 2 554 ? 114.753 131.845 132.112 1.00 84.05  ? 554 ALA D O   1 
ATOM   5450 C  CB  . ALA B 2 554 ? 114.800 131.726 135.436 1.00 84.05  ? 554 ALA D CB  1 
ATOM   5451 N  N   . ILE B 2 555 ? 114.031 133.718 133.129 1.00 85.98  ? 555 ILE D N   1 
ATOM   5452 C  CA  . ILE B 2 555 ? 113.195 134.076 131.982 1.00 85.98  ? 555 ILE D CA  1 
ATOM   5453 C  C   . ILE B 2 555 ? 114.052 134.442 130.776 1.00 85.98  ? 555 ILE D C   1 
ATOM   5454 O  O   . ILE B 2 555 ? 113.681 134.163 129.631 1.00 85.98  ? 555 ILE D O   1 
ATOM   5455 C  CB  . ILE B 2 555 ? 112.203 135.199 132.339 1.00 85.98  ? 555 ILE D CB  1 
ATOM   5456 C  CG1 . ILE B 2 555 ? 111.580 134.955 133.710 1.00 85.98  ? 555 ILE D CG1 1 
ATOM   5457 C  CG2 . ILE B 2 555 ? 111.116 135.302 131.281 1.00 85.98  ? 555 ILE D CG2 1 
ATOM   5458 C  CD1 . ILE B 2 555 ? 110.900 133.604 133.829 1.00 85.98  ? 555 ILE D CD1 1 
ATOM   5459 N  N   . ASP B 2 556 ? 115.205 135.074 131.007 1.00 85.24  ? 556 ASP D N   1 
ATOM   5460 C  CA  . ASP B 2 556 ? 116.112 135.381 129.906 1.00 85.24  ? 556 ASP D CA  1 
ATOM   5461 C  C   . ASP B 2 556 ? 116.564 134.106 129.209 1.00 85.24  ? 556 ASP D C   1 
ATOM   5462 O  O   . ASP B 2 556 ? 116.528 134.007 127.977 1.00 85.24  ? 556 ASP D O   1 
ATOM   5463 C  CB  . ASP B 2 556 ? 117.319 136.162 130.429 1.00 85.24  ? 556 ASP D CB  1 
ATOM   5464 C  CG  . ASP B 2 556 ? 117.283 137.622 130.036 1.00 85.24  ? 556 ASP D CG  1 
ATOM   5465 O  OD1 . ASP B 2 556 ? 118.365 138.240 129.937 1.00 85.24  ? 556 ASP D OD1 1 
ATOM   5466 O  OD2 . ASP B 2 556 ? 116.174 138.155 129.835 1.00 85.24  ? 556 ASP D OD2 1 
ATOM   5467 N  N   . LEU B 2 557 ? 116.978 133.109 129.992 1.00 68.71  ? 557 LEU D N   1 
ATOM   5468 C  CA  . LEU B 2 557 ? 117.416 131.847 129.410 1.00 68.71  ? 557 LEU D CA  1 
ATOM   5469 C  C   . LEU B 2 557 ? 116.264 131.105 128.743 1.00 68.71  ? 557 LEU D C   1 
ATOM   5470 O  O   . LEU B 2 557 ? 116.463 130.459 127.708 1.00 68.71  ? 557 LEU D O   1 
ATOM   5471 C  CB  . LEU B 2 557 ? 118.069 130.978 130.482 1.00 68.71  ? 557 LEU D CB  1 
ATOM   5472 C  CG  . LEU B 2 557 ? 118.797 129.723 130.003 1.00 68.71  ? 557 LEU D CG  1 
ATOM   5473 C  CD1 . LEU B 2 557 ? 119.608 130.015 128.752 1.00 68.71  ? 557 LEU D CD1 1 
ATOM   5474 C  CD2 . LEU B 2 557 ? 119.696 129.209 131.108 1.00 68.71  ? 557 LEU D CD2 1 
ATOM   5475 N  N   . LEU B 2 558 ? 115.062 131.181 129.317 1.00 73.10  ? 558 LEU D N   1 
ATOM   5476 C  CA  . LEU B 2 558 ? 113.906 130.522 128.719 1.00 73.10  ? 558 LEU D CA  1 
ATOM   5477 C  C   . LEU B 2 558 ? 113.558 131.140 127.370 1.00 73.10  ? 558 LEU D C   1 
ATOM   5478 O  O   . LEU B 2 558 ? 113.315 130.424 126.392 1.00 73.10  ? 558 LEU D O   1 
ATOM   5479 C  CB  . LEU B 2 558 ? 112.714 130.600 129.677 1.00 73.10  ? 558 LEU D CB  1 
ATOM   5480 C  CG  . LEU B 2 558 ? 111.642 129.507 129.633 1.00 73.10  ? 558 LEU D CG  1 
ATOM   5481 C  CD1 . LEU B 2 558 ? 110.768 129.593 130.873 1.00 73.10  ? 558 LEU D CD1 1 
ATOM   5482 C  CD2 . LEU B 2 558 ? 110.784 129.600 128.381 1.00 73.10  ? 558 LEU D CD2 1 
ATOM   5483 N  N   . VAL B 2 559 ? 113.531 132.474 127.297 1.00 80.25  ? 559 VAL D N   1 
ATOM   5484 C  CA  . VAL B 2 559 ? 113.180 133.142 126.048 1.00 80.25  ? 559 VAL D CA  1 
ATOM   5485 C  C   . VAL B 2 559 ? 114.324 133.048 125.048 1.00 80.25  ? 559 VAL D C   1 
ATOM   5486 O  O   . VAL B 2 559 ? 114.120 133.223 123.840 1.00 80.25  ? 559 VAL D O   1 
ATOM   5487 C  CB  . VAL B 2 559 ? 112.777 134.606 126.319 1.00 80.25  ? 559 VAL D CB  1 
ATOM   5488 C  CG1 . VAL B 2 559 ? 114.007 135.472 126.542 1.00 80.25  ? 559 VAL D CG1 1 
ATOM   5489 C  CG2 . VAL B 2 559 ? 111.929 135.148 125.178 1.00 80.25  ? 559 VAL D CG2 1 
ATOM   5490 N  N   . ALA B 2 560 ? 115.540 132.768 125.525 1.00 72.52  ? 560 ALA D N   1 
ATOM   5491 C  CA  . ALA B 2 560 ? 116.661 132.592 124.610 1.00 72.52  ? 560 ALA D CA  1 
ATOM   5492 C  C   . ALA B 2 560 ? 116.502 131.339 123.759 1.00 72.52  ? 560 ALA D C   1 
ATOM   5493 O  O   . ALA B 2 560 ? 117.075 131.256 122.667 1.00 72.52  ? 560 ALA D O   1 
ATOM   5494 C  CB  . ALA B 2 560 ? 117.974 132.542 125.390 1.00 72.52  ? 560 ALA D CB  1 
ATOM   5495 N  N   . HIS B 2 561 ? 115.734 130.360 124.235 1.00 66.25  ? 561 HIS D N   1 
ATOM   5496 C  CA  . HIS B 2 561 ? 115.568 129.103 123.515 1.00 66.25  ? 561 HIS D CA  1 
ATOM   5497 C  C   . HIS B 2 561 ? 114.189 128.965 122.884 1.00 66.25  ? 561 HIS D C   1 
ATOM   5498 O  O   . HIS B 2 561 ? 114.071 128.453 121.766 1.00 66.25  ? 561 HIS D O   1 
ATOM   5499 C  CB  . HIS B 2 561 ? 115.827 127.924 124.454 1.00 66.25  ? 561 HIS D CB  1 
ATOM   5500 C  CG  . HIS B 2 561 ? 117.277 127.677 124.720 1.00 66.25  ? 561 HIS D CG  1 
ATOM   5501 N  ND1 . HIS B 2 561 ? 117.994 128.393 125.654 1.00 66.25  ? 561 HIS D ND1 1 
ATOM   5502 C  CD2 . HIS B 2 561 ? 118.148 126.798 124.171 1.00 66.25  ? 561 HIS D CD2 1 
ATOM   5503 C  CE1 . HIS B 2 561 ? 119.243 127.966 125.669 1.00 66.25  ? 561 HIS D CE1 1 
ATOM   5504 N  NE2 . HIS B 2 561 ? 119.363 126.997 124.780 1.00 66.25  ? 561 HIS D NE2 1 
ATOM   5505 N  N   . MET B 2 562 ? 113.142 129.408 123.575 1.00 83.21  ? 562 MET D N   1 
ATOM   5506 C  CA  . MET B 2 562 ? 111.784 129.293 123.067 1.00 83.21  ? 562 MET D CA  1 
ATOM   5507 C  C   . MET B 2 562 ? 111.360 130.619 122.457 1.00 83.21  ? 562 MET D C   1 
ATOM   5508 O  O   . MET B 2 562 ? 111.213 131.609 123.189 1.00 83.21  ? 562 MET D O   1 
ATOM   5509 C  CB  . MET B 2 562 ? 110.827 128.883 124.184 1.00 83.21  ? 562 MET D CB  1 
ATOM   5510 C  CG  . MET B 2 562 ? 111.359 127.750 125.050 1.00 83.21  ? 562 MET D CG  1 
ATOM   5511 S  SD  . MET B 2 562 ? 110.084 126.602 125.600 1.00 83.21  ? 562 MET D SD  1 
ATOM   5512 C  CE  . MET B 2 562 ? 111.067 125.421 126.519 1.00 83.21  ? 562 MET D CE  1 
ATOM   5513 N  N   . PRO B 2 563 ? 111.169 130.691 121.140 1.00 101.52 ? 563 PRO D N   1 
ATOM   5514 C  CA  . PRO B 2 563 ? 110.824 131.973 120.509 1.00 101.52 ? 563 PRO D CA  1 
ATOM   5515 C  C   . PRO B 2 563 ? 109.488 132.504 121.007 1.00 101.52 ? 563 PRO D C   1 
ATOM   5516 O  O   . PRO B 2 563 ? 108.525 131.753 121.175 1.00 101.52 ? 563 PRO D O   1 
ATOM   5517 C  CB  . PRO B 2 563 ? 110.775 131.630 119.015 1.00 101.52 ? 563 PRO D CB  1 
ATOM   5518 C  CG  . PRO B 2 563 ? 111.556 130.357 118.881 1.00 101.52 ? 563 PRO D CG  1 
ATOM   5519 C  CD  . PRO B 2 563 ? 111.318 129.610 120.153 1.00 101.52 ? 563 PRO D CD  1 
ATOM   5520 N  N   . GLY B 2 564 ? 109.437 133.816 121.231 1.00 113.86 ? 564 GLY D N   1 
ATOM   5521 C  CA  . GLY B 2 564 ? 108.213 134.460 121.670 1.00 113.86 ? 564 GLY D CA  1 
ATOM   5522 C  C   . GLY B 2 564 ? 107.636 133.909 122.952 1.00 113.86 ? 564 GLY D C   1 
ATOM   5523 O  O   . GLY B 2 564 ? 106.421 133.712 123.040 1.00 113.86 ? 564 GLY D O   1 
ATOM   5524 N  N   . ALA B 2 565 ? 108.475 133.649 123.956 1.00 118.87 ? 565 ALA D N   1 
ATOM   5525 C  CA  . ALA B 2 565 ? 107.986 133.006 125.170 1.00 118.87 ? 565 ALA D CA  1 
ATOM   5526 C  C   . ALA B 2 565 ? 107.208 133.983 126.042 1.00 118.87 ? 565 ALA D C   1 
ATOM   5527 O  O   . ALA B 2 565 ? 105.997 133.829 126.240 1.00 118.87 ? 565 ALA D O   1 
ATOM   5528 C  CB  . ALA B 2 565 ? 109.154 132.401 125.948 1.00 118.87 ? 565 ALA D CB  1 
ATOM   5529 N  N   . TYR B 2 566 ? 107.887 134.999 126.573 1.00 122.34 ? 566 TYR D N   1 
ATOM   5530 C  CA  . TYR B 2 566 ? 107.233 135.973 127.437 1.00 122.34 ? 566 TYR D CA  1 
ATOM   5531 C  C   . TYR B 2 566 ? 107.680 137.389 127.098 1.00 122.34 ? 566 TYR D C   1 
ATOM   5532 O  O   . TYR B 2 566 ? 107.075 138.364 127.557 1.00 122.34 ? 566 TYR D O   1 
ATOM   5533 C  CB  . TYR B 2 566 ? 107.519 135.657 128.906 1.00 122.34 ? 566 TYR D CB  1 
ATOM   5534 C  CG  . TYR B 2 566 ? 107.223 134.223 129.286 1.00 122.34 ? 566 TYR D CG  1 
ATOM   5535 C  CD1 . TYR B 2 566 ? 105.933 133.819 129.599 1.00 122.34 ? 566 TYR D CD1 1 
ATOM   5536 C  CD2 . TYR B 2 566 ? 108.236 133.273 129.329 1.00 122.34 ? 566 TYR D CD2 1 
ATOM   5537 C  CE1 . TYR B 2 566 ? 105.659 132.508 129.945 1.00 122.34 ? 566 TYR D CE1 1 
ATOM   5538 C  CE2 . TYR B 2 566 ? 107.971 131.961 129.673 1.00 122.34 ? 566 TYR D CE2 1 
ATOM   5539 C  CZ  . TYR B 2 566 ? 106.682 131.584 129.980 1.00 122.34 ? 566 TYR D CZ  1 
ATOM   5540 O  OH  . TYR B 2 566 ? 106.413 130.279 130.323 1.00 122.34 ? 566 TYR D OH  1 
ATOM   5541 N  N   . SER B 2 567 ? 108.751 137.502 126.308 1.00 116.70 ? 567 SER D N   1 
ATOM   5542 C  CA  . SER B 2 567 ? 109.325 138.791 125.912 1.00 116.70 ? 567 SER D CA  1 
ATOM   5543 C  C   . SER B 2 567 ? 109.795 139.596 127.121 1.00 116.70 ? 567 SER D C   1 
ATOM   5544 O  O   . SER B 2 567 ? 109.926 140.821 127.055 1.00 116.70 ? 567 SER D O   1 
ATOM   5545 C  CB  . SER B 2 567 ? 108.339 139.607 125.070 1.00 116.70 ? 567 SER D CB  1 
ATOM   5546 O  OG  . SER B 2 567 ? 109.008 140.630 124.353 1.00 116.70 ? 567 SER D OG  1 
ATOM   5547 N  N   . LYS B 2 568 ? 110.034 138.906 128.240 1.00 110.64 ? 568 LYS D N   1 
ATOM   5548 C  CA  . LYS B 2 568 ? 110.600 139.498 129.450 1.00 110.64 ? 568 LYS D CA  1 
ATOM   5549 C  C   . LYS B 2 568 ? 109.717 140.594 130.036 1.00 110.64 ? 568 LYS D C   1 
ATOM   5550 O  O   . LYS B 2 568 ? 110.135 141.303 130.957 1.00 110.64 ? 568 LYS D O   1 
ATOM   5551 C  CB  . LYS B 2 568 ? 111.996 140.060 129.166 1.00 110.64 ? 568 LYS D CB  1 
ATOM   5552 C  CG  . LYS B 2 568 ? 112.949 139.077 128.505 1.00 110.64 ? 568 LYS D CG  1 
ATOM   5553 C  CD  . LYS B 2 568 ? 114.201 139.774 127.987 1.00 110.64 ? 568 LYS D CD  1 
ATOM   5554 C  CE  . LYS B 2 568 ? 114.637 140.913 128.899 1.00 110.64 ? 568 LYS D CE  1 
ATOM   5555 N  NZ  . LYS B 2 568 ? 115.085 140.423 130.234 1.00 110.64 ? 568 LYS D NZ  1 
ATOM   5556 N  N   . ALA B 2 569 ? 108.495 140.743 129.518 1.00 118.96 ? 569 ALA D N   1 
ATOM   5557 C  CA  . ALA B 2 569 ? 107.646 141.844 129.959 1.00 118.96 ? 569 ALA D CA  1 
ATOM   5558 C  C   . ALA B 2 569 ? 106.483 141.347 130.807 1.00 118.96 ? 569 ALA D C   1 
ATOM   5559 O  O   . ALA B 2 569 ? 106.259 141.844 131.916 1.00 118.96 ? 569 ALA D O   1 
ATOM   5560 C  CB  . ALA B 2 569 ? 107.133 142.626 128.750 1.00 118.96 ? 569 ALA D CB  1 
ATOM   5561 N  N   . GLU B 2 570 ? 105.726 140.372 130.297 1.00 127.54 ? 570 GLU D N   1 
ATOM   5562 C  CA  . GLU B 2 570 ? 104.550 139.892 131.016 1.00 127.54 ? 570 GLU D CA  1 
ATOM   5563 C  C   . GLU B 2 570 ? 104.936 139.247 132.342 1.00 127.54 ? 570 GLU D C   1 
ATOM   5564 O  O   . GLU B 2 570 ? 104.295 139.488 133.372 1.00 127.54 ? 570 GLU D O   1 
ATOM   5565 C  CB  . GLU B 2 570 ? 103.769 138.909 130.143 1.00 127.54 ? 570 GLU D CB  1 
ATOM   5566 C  CG  . GLU B 2 570 ? 102.617 138.222 130.858 1.00 127.54 ? 570 GLU D CG  1 
ATOM   5567 C  CD  . GLU B 2 570 ? 101.495 139.177 131.218 1.00 127.54 ? 570 GLU D CD  1 
ATOM   5568 O  OE1 . GLU B 2 570 ? 101.358 140.221 130.546 1.00 127.54 ? 570 GLU D OE1 1 
ATOM   5569 O  OE2 . GLU B 2 570 ? 100.748 138.883 132.175 1.00 127.54 ? 570 GLU D OE2 1 
ATOM   5570 N  N   . MET B 2 571 ? 105.987 138.423 132.336 1.00 129.88 ? 571 MET D N   1 
ATOM   5571 C  CA  . MET B 2 571 ? 106.412 137.767 133.569 1.00 129.88 ? 571 MET D CA  1 
ATOM   5572 C  C   . MET B 2 571 ? 106.901 138.778 134.598 1.00 129.88 ? 571 MET D C   1 
ATOM   5573 O  O   . MET B 2 571 ? 106.537 138.695 135.776 1.00 129.88 ? 571 MET D O   1 
ATOM   5574 C  CB  . MET B 2 571 ? 107.501 136.738 133.271 1.00 129.88 ? 571 MET D CB  1 
ATOM   5575 C  CG  . MET B 2 571 ? 107.015 135.533 132.491 1.00 129.88 ? 571 MET D CG  1 
ATOM   5576 S  SD  . MET B 2 571 ? 105.579 134.756 133.255 1.00 129.88 ? 571 MET D SD  1 
ATOM   5577 C  CE  . MET B 2 571 ? 106.299 134.126 134.769 1.00 129.88 ? 571 MET D CE  1 
ATOM   5578 N  N   . LEU B 2 572 ? 107.720 139.742 134.172 1.00 126.61 ? 572 LEU D N   1 
ATOM   5579 C  CA  . LEU B 2 572 ? 108.234 140.742 135.103 1.00 126.61 ? 572 LEU D CA  1 
ATOM   5580 C  C   . LEU B 2 572 ? 107.100 141.594 135.661 1.00 126.61 ? 572 LEU D C   1 
ATOM   5581 O  O   . LEU B 2 572 ? 107.068 141.897 136.860 1.00 126.61 ? 572 LEU D O   1 
ATOM   5582 C  CB  . LEU B 2 572 ? 109.297 141.598 134.404 1.00 126.61 ? 572 LEU D CB  1 
ATOM   5583 C  CG  . LEU B 2 572 ? 110.254 142.538 135.156 1.00 126.61 ? 572 LEU D CG  1 
ATOM   5584 C  CD1 . LEU B 2 572 ? 109.568 143.660 135.924 1.00 126.61 ? 572 LEU D CD1 1 
ATOM   5585 C  CD2 . LEU B 2 572 ? 111.120 141.722 136.105 1.00 126.61 ? 572 LEU D CD2 1 
ATOM   5586 N  N   . GLU B 2 573 ? 106.150 141.979 134.807 1.00 128.52 ? 573 GLU D N   1 
ATOM   5587 C  CA  . GLU B 2 573 ? 105.012 142.763 135.276 1.00 128.52 ? 573 GLU D CA  1 
ATOM   5588 C  C   . GLU B 2 573 ? 104.153 141.962 136.246 1.00 128.52 ? 573 GLU D C   1 
ATOM   5589 O  O   . GLU B 2 573 ? 103.597 142.519 137.200 1.00 128.52 ? 573 GLU D O   1 
ATOM   5590 C  CB  . GLU B 2 573 ? 104.178 143.243 134.088 1.00 128.52 ? 573 GLU D CB  1 
ATOM   5591 C  CG  . GLU B 2 573 ? 104.769 144.440 133.362 1.00 128.52 ? 573 GLU D CG  1 
ATOM   5592 C  CD  . GLU B 2 573 ? 103.820 145.024 132.334 1.00 128.52 ? 573 GLU D CD  1 
ATOM   5593 O  OE1 . GLU B 2 573 ? 102.601 144.772 132.437 1.00 128.52 ? 573 GLU D OE1 1 
ATOM   5594 O  OE2 . GLU B 2 573 ? 104.293 145.737 131.424 1.00 128.52 ? 573 GLU D OE2 1 
ATOM   5595 N  N   . LYS B 2 574 ? 104.026 140.653 136.014 1.00 127.70 ? 574 LYS D N   1 
ATOM   5596 C  CA  . LYS B 2 574 ? 103.247 139.816 136.919 1.00 127.70 ? 574 LYS D CA  1 
ATOM   5597 C  C   . LYS B 2 574 ? 103.866 139.756 138.309 1.00 127.70 ? 574 LYS D C   1 
ATOM   5598 O  O   . LYS B 2 574 ? 103.144 139.827 139.310 1.00 127.70 ? 574 LYS D O   1 
ATOM   5599 C  CB  . LYS B 2 574 ? 103.104 138.410 136.340 1.00 127.70 ? 574 LYS D CB  1 
ATOM   5600 C  CG  . LYS B 2 574 ? 101.779 138.173 135.641 1.00 127.70 ? 574 LYS D CG  1 
ATOM   5601 C  CD  . LYS B 2 574 ? 100.637 138.189 136.641 1.00 127.70 ? 574 LYS D CD  1 
ATOM   5602 C  CE  . LYS B 2 574 ? 99.300  137.992 135.955 1.00 127.70 ? 574 LYS D CE  1 
ATOM   5603 N  NZ  . LYS B 2 574 ? 98.283  137.418 136.879 1.00 127.70 ? 574 LYS D NZ  1 
ATOM   5604 N  N   . CYS B 2 575 ? 105.191 139.619 138.396 1.00 129.36 ? 575 CYS D N   1 
ATOM   5605 C  CA  . CYS B 2 575 ? 105.847 139.635 139.700 1.00 129.36 ? 575 CYS D CA  1 
ATOM   5606 C  C   . CYS B 2 575 ? 105.688 140.991 140.375 1.00 129.36 ? 575 CYS D C   1 
ATOM   5607 O  O   . CYS B 2 575 ? 105.432 141.066 141.582 1.00 129.36 ? 575 CYS D O   1 
ATOM   5608 C  CB  . CYS B 2 575 ? 107.325 139.269 139.558 1.00 129.36 ? 575 CYS D CB  1 
ATOM   5609 S  SG  . CYS B 2 575 ? 107.653 137.831 138.516 1.00 129.36 ? 575 CYS D SG  1 
ATOM   5610 N  N   . ARG B 2 576 ? 105.829 142.077 139.609 1.00 133.28 ? 576 ARG D N   1 
ATOM   5611 C  CA  . ARG B 2 576 ? 105.648 143.413 140.169 1.00 133.28 ? 576 ARG D CA  1 
ATOM   5612 C  C   . ARG B 2 576 ? 104.243 143.623 140.715 1.00 133.28 ? 576 ARG D C   1 
ATOM   5613 O  O   . ARG B 2 576 ? 104.064 144.407 141.654 1.00 133.28 ? 576 ARG D O   1 
ATOM   5614 C  CB  . ARG B 2 576 ? 105.963 144.478 139.118 1.00 133.28 ? 576 ARG D CB  1 
ATOM   5615 C  CG  . ARG B 2 576 ? 107.415 144.504 138.678 1.00 133.28 ? 576 ARG D CG  1 
ATOM   5616 C  CD  . ARG B 2 576 ? 108.335 144.856 139.835 1.00 133.28 ? 576 ARG D CD  1 
ATOM   5617 N  NE  . ARG B 2 576 ? 108.184 146.246 140.250 1.00 133.28 ? 576 ARG D NE  1 
ATOM   5618 C  CZ  . ARG B 2 576 ? 107.665 146.629 141.408 1.00 133.28 ? 576 ARG D CZ  1 
ATOM   5619 N  NH1 . ARG B 2 576 ? 107.232 145.750 142.297 1.00 133.28 ? 576 ARG D NH1 1 
ATOM   5620 N  NH2 . ARG B 2 576 ? 107.577 147.928 141.682 1.00 133.28 ? 576 ARG D NH2 1 
ATOM   5621 N  N   . MET B 2 577 ? 103.245 142.946 140.149 1.00 138.46 ? 577 MET D N   1 
ATOM   5622 C  CA  . MET B 2 577 ? 101.899 142.981 140.702 1.00 138.46 ? 577 MET D CA  1 
ATOM   5623 C  C   . MET B 2 577 ? 101.782 142.156 141.978 1.00 138.46 ? 577 MET D C   1 
ATOM   5624 O  O   . MET B 2 577 ? 100.949 142.473 142.835 1.00 138.46 ? 577 MET D O   1 
ATOM   5625 C  CB  . MET B 2 577 ? 100.901 142.488 139.647 1.00 138.46 ? 577 MET D CB  1 
ATOM   5626 C  CG  . MET B 2 577 ? 99.562  142.001 140.183 1.00 138.46 ? 577 MET D CG  1 
ATOM   5627 S  SD  . MET B 2 577 ? 98.280  141.922 138.915 1.00 138.46 ? 577 MET D SD  1 
ATOM   5628 C  CE  . MET B 2 577 ? 98.858  143.160 137.756 1.00 138.46 ? 577 MET D CE  1 
ATOM   5629 N  N   . MET B 2 578 ? 102.627 141.136 142.142 1.00 134.11 ? 578 MET D N   1 
ATOM   5630 C  CA  . MET B 2 578 ? 102.522 140.203 143.254 1.00 134.11 ? 578 MET D CA  1 
ATOM   5631 C  C   . MET B 2 578 ? 103.533 140.437 144.369 1.00 134.11 ? 578 MET D C   1 
ATOM   5632 O  O   . MET B 2 578 ? 103.240 140.091 145.519 1.00 134.11 ? 578 MET D O   1 
ATOM   5633 C  CB  . MET B 2 578 ? 102.671 138.758 142.744 1.00 134.11 ? 578 MET D CB  1 
ATOM   5634 C  CG  . MET B 2 578 ? 102.446 137.680 143.792 1.00 134.11 ? 578 MET D CG  1 
ATOM   5635 S  SD  . MET B 2 578 ? 101.651 136.213 143.111 1.00 134.11 ? 578 MET D SD  1 
ATOM   5636 C  CE  . MET B 2 578 ? 101.598 135.156 144.555 1.00 134.11 ? 578 MET D CE  1 
ATOM   5637 N  N   . ASP B 2 579 ? 104.691 141.033 144.081 1.00 133.84 ? 579 ASP D N   1 
ATOM   5638 C  CA  . ASP B 2 579 ? 105.738 141.164 145.089 1.00 133.84 ? 579 ASP D CA  1 
ATOM   5639 C  C   . ASP B 2 579 ? 105.422 142.274 146.088 1.00 133.84 ? 579 ASP D C   1 
ATOM   5640 O  O   . ASP B 2 579 ? 106.179 143.242 146.211 1.00 133.84 ? 579 ASP D O   1 
ATOM   5641 C  CB  . ASP B 2 579 ? 107.096 141.415 144.424 1.00 133.84 ? 579 ASP D CB  1 
ATOM   5642 C  CG  . ASP B 2 579 ? 107.086 142.617 143.496 1.00 133.84 ? 579 ASP D CG  1 
ATOM   5643 O  OD1 . ASP B 2 579 ? 106.015 143.239 143.335 1.00 133.84 ? 579 ASP D OD1 1 
ATOM   5644 O  OD2 . ASP B 2 579 ? 108.149 142.938 142.925 1.00 133.84 ? 579 ASP D OD2 1 
ATOM   5645 N  N   . LEU B 2 580 ? 104.307 142.137 146.810 1.00 133.07 ? 580 LEU D N   1 
ATOM   5646 C  CA  . LEU B 2 580 ? 103.963 143.125 147.826 1.00 133.07 ? 580 LEU D CA  1 
ATOM   5647 C  C   . LEU B 2 580 ? 104.983 143.143 148.956 1.00 133.07 ? 580 LEU D C   1 
ATOM   5648 O  O   . LEU B 2 580 ? 105.334 144.217 149.459 1.00 133.07 ? 580 LEU D O   1 
ATOM   5649 C  CB  . LEU B 2 580 ? 102.562 142.853 148.376 1.00 133.07 ? 580 LEU D CB  1 
ATOM   5650 C  CG  . LEU B 2 580 ? 101.381 143.420 147.582 1.00 133.07 ? 580 LEU D CG  1 
ATOM   5651 C  CD1 . LEU B 2 580 ? 101.113 142.604 146.324 1.00 133.07 ? 580 LEU D CD1 1 
ATOM   5652 C  CD2 . LEU B 2 580 ? 100.135 143.495 148.451 1.00 133.07 ? 580 LEU D CD2 1 
ATOM   5653 N  N   . ASN B 2 581 ? 105.471 141.972 149.366 1.00 135.02 ? 581 ASN D N   1 
ATOM   5654 C  CA  . ASN B 2 581 ? 106.481 141.858 150.410 1.00 135.02 ? 581 ASN D CA  1 
ATOM   5655 C  C   . ASN B 2 581 ? 107.859 141.544 149.833 1.00 135.02 ? 581 ASN D C   1 
ATOM   5656 O  O   . ASN B 2 581 ? 108.740 141.054 150.544 1.00 135.02 ? 581 ASN D O   1 
ATOM   5657 C  CB  . ASN B 2 581 ? 106.075 140.799 151.434 1.00 135.02 ? 581 ASN D CB  1 
ATOM   5658 C  CG  . ASN B 2 581 ? 105.926 139.421 150.821 1.00 135.02 ? 581 ASN D CG  1 
ATOM   5659 O  OD1 . ASN B 2 581 ? 104.840 139.036 150.387 1.00 135.02 ? 581 ASN D OD1 1 
ATOM   5660 N  ND2 . ASN B 2 581 ? 107.018 138.666 150.789 1.00 135.02 ? 581 ASN D ND2 1 
ATOM   5661 N  N   . GLY B 2 582 ? 108.055 141.819 148.548 1.00 129.71 ? 582 GLY D N   1 
ATOM   5662 C  CA  . GLY B 2 582 ? 109.333 141.586 147.913 1.00 129.71 ? 582 GLY D CA  1 
ATOM   5663 C  C   . GLY B 2 582 ? 109.515 140.151 147.452 1.00 129.71 ? 582 GLY D C   1 
ATOM   5664 O  O   . GLY B 2 582 ? 108.622 139.304 147.544 1.00 129.71 ? 582 GLY D O   1 
ATOM   5665 N  N   . ASP B 2 583 ? 110.713 139.889 146.937 1.00 122.45 ? 583 ASP D N   1 
ATOM   5666 C  CA  . ASP B 2 583 ? 111.060 138.561 146.455 1.00 122.45 ? 583 ASP D CA  1 
ATOM   5667 C  C   . ASP B 2 583 ? 111.092 137.558 147.602 1.00 122.45 ? 583 ASP D C   1 
ATOM   5668 O  O   . ASP B 2 583 ? 111.439 137.889 148.739 1.00 122.45 ? 583 ASP D O   1 
ATOM   5669 C  CB  . ASP B 2 583 ? 112.416 138.590 145.750 1.00 122.45 ? 583 ASP D CB  1 
ATOM   5670 C  CG  . ASP B 2 583 ? 113.394 139.544 146.409 1.00 122.45 ? 583 ASP D CG  1 
ATOM   5671 O  OD1 . ASP B 2 583 ? 113.031 140.157 147.435 1.00 122.45 ? 583 ASP D OD1 1 
ATOM   5672 O  OD2 . ASP B 2 583 ? 114.525 139.683 145.899 1.00 122.45 ? 583 ASP D OD2 1 
ATOM   5673 N  N   . GLY B 2 584 ? 110.723 136.316 147.295 1.00 102.97 ? 584 GLY D N   1 
ATOM   5674 C  CA  . GLY B 2 584 ? 110.712 135.283 148.311 1.00 102.97 ? 584 GLY D CA  1 
ATOM   5675 C  C   . GLY B 2 584 ? 110.316 133.901 147.833 1.00 102.97 ? 584 GLY D C   1 
ATOM   5676 O  O   . GLY B 2 584 ? 110.768 133.435 146.783 1.00 102.97 ? 584 GLY D O   1 
ATOM   5677 N  N   . LYS B 2 585 ? 109.461 133.242 148.611 1.00 106.40 ? 585 LYS D N   1 
ATOM   5678 C  CA  . LYS B 2 585 ? 109.121 131.847 148.367 1.00 106.40 ? 585 LYS D CA  1 
ATOM   5679 C  C   . LYS B 2 585 ? 108.293 131.699 147.096 1.00 106.40 ? 585 LYS D C   1 
ATOM   5680 O  O   . LYS B 2 585 ? 107.641 132.643 146.643 1.00 106.40 ? 585 LYS D O   1 
ATOM   5681 C  CB  . LYS B 2 585 ? 108.346 131.290 149.564 1.00 106.40 ? 585 LYS D CB  1 
ATOM   5682 C  CG  . LYS B 2 585 ? 108.258 129.773 149.631 1.00 106.40 ? 585 LYS D CG  1 
ATOM   5683 C  CD  . LYS B 2 585 ? 109.383 129.195 150.471 1.00 106.40 ? 585 LYS D CD  1 
ATOM   5684 C  CE  . LYS B 2 585 ? 109.230 129.587 151.933 1.00 106.40 ? 585 LYS D CE  1 
ATOM   5685 N  NZ  . LYS B 2 585 ? 110.117 128.788 152.823 1.00 106.40 ? 585 LYS D NZ  1 
ATOM   5686 N  N   . VAL B 2 586 ? 108.328 130.499 146.516 1.00 114.55 ? 586 VAL D N   1 
ATOM   5687 C  CA  . VAL B 2 586 ? 107.437 130.143 145.419 1.00 114.55 ? 586 VAL D CA  1 
ATOM   5688 C  C   . VAL B 2 586 ? 106.034 130.013 145.994 1.00 114.55 ? 586 VAL D C   1 
ATOM   5689 O  O   . VAL B 2 586 ? 105.723 129.036 146.685 1.00 114.55 ? 586 VAL D O   1 
ATOM   5690 C  CB  . VAL B 2 586 ? 107.883 128.844 144.725 1.00 114.55 ? 586 VAL D CB  1 
ATOM   5691 C  CG1 . VAL B 2 586 ? 106.918 128.477 143.610 1.00 114.55 ? 586 VAL D CG1 1 
ATOM   5692 C  CG2 . VAL B 2 586 ? 109.300 128.987 144.187 1.00 114.55 ? 586 VAL D CG2 1 
ATOM   5693 N  N   . ASP B 2 587 ? 105.177 130.993 145.712 1.00 128.35 ? 587 ASP D N   1 
ATOM   5694 C  CA  . ASP B 2 587 ? 103.912 131.117 146.426 1.00 128.35 ? 587 ASP D CA  1 
ATOM   5695 C  C   . ASP B 2 587 ? 102.828 130.206 145.861 1.00 128.35 ? 587 ASP D C   1 
ATOM   5696 O  O   . ASP B 2 587 ? 101.721 130.665 145.562 1.00 128.35 ? 587 ASP D O   1 
ATOM   5697 C  CB  . ASP B 2 587 ? 103.440 132.573 146.405 1.00 128.35 ? 587 ASP D CB  1 
ATOM   5698 C  CG  . ASP B 2 587 ? 102.769 132.986 147.699 1.00 128.35 ? 587 ASP D CG  1 
ATOM   5699 O  OD1 . ASP B 2 587 ? 102.911 132.257 148.703 1.00 128.35 ? 587 ASP D OD1 1 
ATOM   5700 O  OD2 . ASP B 2 587 ? 102.100 134.040 147.712 1.00 128.35 ? 587 ASP D OD2 1 
ATOM   5701 N  N   . LEU B 2 588 ? 103.138 128.924 145.721 1.00 130.40 ? 588 LEU D N   1 
ATOM   5702 C  CA  . LEU B 2 588 ? 102.165 127.862 145.448 1.00 130.40 ? 588 LEU D CA  1 
ATOM   5703 C  C   . LEU B 2 588 ? 101.341 128.193 144.199 1.00 130.40 ? 588 LEU D C   1 
ATOM   5704 O  O   . LEU B 2 588 ? 101.863 128.732 143.218 1.00 130.40 ? 588 LEU D O   1 
ATOM   5705 C  CB  . LEU B 2 588 ? 101.344 127.624 146.703 1.00 130.40 ? 588 LEU D CB  1 
ATOM   5706 C  CG  . LEU B 2 588 ? 102.138 127.422 147.996 1.00 130.40 ? 588 LEU D CG  1 
ATOM   5707 C  CD1 . LEU B 2 588 ? 101.205 127.121 149.159 1.00 130.40 ? 588 LEU D CD1 1 
ATOM   5708 C  CD2 . LEU B 2 588 ? 103.167 126.314 147.829 1.00 130.40 ? 588 LEU D CD2 1 
ATOM   5709 N  N   . ASN B 2 589 ? 100.045 127.866 144.235 1.00 138.42 ? 589 ASN D N   1 
ATOM   5710 C  CA  . ASN B 2 589 ? 99.201  127.981 143.048 1.00 138.42 ? 589 ASN D CA  1 
ATOM   5711 C  C   . ASN B 2 589 ? 99.027  129.431 142.611 1.00 138.42 ? 589 ASN D C   1 
ATOM   5712 O  O   . ASN B 2 589 ? 99.108  129.738 141.416 1.00 138.42 ? 589 ASN D O   1 
ATOM   5713 C  CB  . ASN B 2 589 ? 97.840  127.338 143.312 1.00 138.42 ? 589 ASN D CB  1 
ATOM   5714 C  CG  . ASN B 2 589 ? 96.928  127.387 142.102 1.00 138.42 ? 589 ASN D CG  1 
ATOM   5715 O  OD1 . ASN B 2 589 ? 97.364  127.167 140.972 1.00 138.42 ? 589 ASN D OD1 1 
ATOM   5716 N  ND2 . ASN B 2 589 ? 95.653  127.677 142.334 1.00 138.42 ? 589 ASN D ND2 1 
ATOM   5717 N  N   . GLU B 2 590 ? 98.777  130.337 143.561 1.00 133.10 ? 590 GLU D N   1 
ATOM   5718 C  CA  . GLU B 2 590 ? 98.542  131.733 143.208 1.00 133.10 ? 590 GLU D CA  1 
ATOM   5719 C  C   . GLU B 2 590 ? 99.757  132.376 142.553 1.00 133.10 ? 590 GLU D C   1 
ATOM   5720 O  O   . GLU B 2 590 ? 99.606  133.365 141.829 1.00 133.10 ? 590 GLU D O   1 
ATOM   5721 C  CB  . GLU B 2 590 ? 98.128  132.533 144.445 1.00 133.10 ? 590 GLU D CB  1 
ATOM   5722 C  CG  . GLU B 2 590 ? 99.113  132.462 145.600 1.00 133.10 ? 590 GLU D CG  1 
ATOM   5723 C  CD  . GLU B 2 590 ? 98.705  131.452 146.654 1.00 133.10 ? 590 GLU D CD  1 
ATOM   5724 O  OE1 . GLU B 2 590 ? 98.272  130.342 146.280 1.00 133.10 ? 590 GLU D OE1 1 
ATOM   5725 O  OE2 . GLU B 2 590 ? 98.818  131.767 147.857 1.00 133.10 ? 590 GLU D OE2 1 
ATOM   5726 N  N   . PHE B 2 591 ? 100.953 131.838 142.793 1.00 124.28 ? 591 PHE D N   1 
ATOM   5727 C  CA  . PHE B 2 591 ? 102.141 132.333 142.107 1.00 124.28 ? 591 PHE D CA  1 
ATOM   5728 C  C   . PHE B 2 591 ? 102.182 131.840 140.665 1.00 124.28 ? 591 PHE D C   1 
ATOM   5729 O  O   . PHE B 2 591 ? 102.672 132.540 139.771 1.00 124.28 ? 591 PHE D O   1 
ATOM   5730 C  CB  . PHE B 2 591 ? 103.391 131.906 142.876 1.00 124.28 ? 591 PHE D CB  1 
ATOM   5731 C  CG  . PHE B 2 591 ? 104.645 131.932 142.061 1.00 124.28 ? 591 PHE D CG  1 
ATOM   5732 C  CD1 . PHE B 2 591 ? 105.312 133.122 141.829 1.00 124.28 ? 591 PHE D CD1 1 
ATOM   5733 C  CD2 . PHE B 2 591 ? 105.170 130.763 141.543 1.00 124.28 ? 591 PHE D CD2 1 
ATOM   5734 C  CE1 . PHE B 2 591 ? 106.472 133.145 141.083 1.00 124.28 ? 591 PHE D CE1 1 
ATOM   5735 C  CE2 . PHE B 2 591 ? 106.325 130.780 140.801 1.00 124.28 ? 591 PHE D CE2 1 
ATOM   5736 C  CZ  . PHE B 2 591 ? 106.979 131.972 140.568 1.00 124.28 ? 591 PHE D CZ  1 
ATOM   5737 N  N   . LEU B 2 592 ? 101.666 130.632 140.418 1.00 129.12 ? 592 LEU D N   1 
ATOM   5738 C  CA  . LEU B 2 592 ? 101.584 130.117 139.056 1.00 129.12 ? 592 LEU D CA  1 
ATOM   5739 C  C   . LEU B 2 592 ? 100.457 130.769 138.266 1.00 129.12 ? 592 LEU D C   1 
ATOM   5740 O  O   . LEU B 2 592 ? 100.356 130.557 137.050 1.00 129.12 ? 592 LEU D O   1 
ATOM   5741 C  CB  . LEU B 2 592 ? 101.405 128.598 139.078 1.00 129.12 ? 592 LEU D CB  1 
ATOM   5742 C  CG  . LEU B 2 592 ? 102.450 127.815 139.875 1.00 129.12 ? 592 LEU D CG  1 
ATOM   5743 C  CD1 . LEU B 2 592 ? 102.188 126.321 139.783 1.00 129.12 ? 592 LEU D CD1 1 
ATOM   5744 C  CD2 . LEU B 2 592 ? 103.854 128.147 139.397 1.00 129.12 ? 592 LEU D CD2 1 
ATOM   5745 N  N   . GLU B 2 593 ? 99.602  131.552 138.928 1.00 135.32 ? 593 GLU D N   1 
ATOM   5746 C  CA  . GLU B 2 593 ? 98.607  132.330 138.203 1.00 135.32 ? 593 GLU D CA  1 
ATOM   5747 C  C   . GLU B 2 593 ? 99.256  133.319 137.247 1.00 135.32 ? 593 GLU D C   1 
ATOM   5748 O  O   . GLU B 2 593 ? 98.630  133.706 136.256 1.00 135.32 ? 593 GLU D O   1 
ATOM   5749 C  CB  . GLU B 2 593 ? 97.690  133.065 139.183 1.00 135.32 ? 593 GLU D CB  1 
ATOM   5750 C  CG  . GLU B 2 593 ? 96.567  132.205 139.742 1.00 135.32 ? 593 GLU D CG  1 
ATOM   5751 C  CD  . GLU B 2 593 ? 95.321  132.232 138.878 1.00 135.32 ? 593 GLU D CD  1 
ATOM   5752 O  OE1 . GLU B 2 593 ? 95.420  132.619 137.694 1.00 135.32 ? 593 GLU D OE1 1 
ATOM   5753 O  OE2 . GLU B 2 593 ? 94.240  131.863 139.383 1.00 135.32 ? 593 GLU D OE2 1 
ATOM   5754 N  N   . ALA B 2 594 ? 100.498 133.726 137.517 1.00 129.54 ? 594 ALA D N   1 
ATOM   5755 C  CA  . ALA B 2 594 ? 101.242 134.529 136.553 1.00 129.54 ? 594 ALA D CA  1 
ATOM   5756 C  C   . ALA B 2 594 ? 101.396 133.783 135.234 1.00 129.54 ? 594 ALA D C   1 
ATOM   5757 O  O   . ALA B 2 594 ? 101.087 134.320 134.163 1.00 129.54 ? 594 ALA D O   1 
ATOM   5758 C  CB  . ALA B 2 594 ? 102.608 134.902 137.127 1.00 129.54 ? 594 ALA D CB  1 
ATOM   5759 N  N   . PHE B 2 595 ? 101.859 132.531 135.296 1.00 122.50 ? 595 PHE D N   1 
ATOM   5760 C  CA  . PHE B 2 595 ? 101.967 131.714 134.091 1.00 122.50 ? 595 PHE D CA  1 
ATOM   5761 C  C   . PHE B 2 595 ? 100.601 131.480 133.461 1.00 122.50 ? 595 PHE D C   1 
ATOM   5762 O  O   . PHE B 2 595 ? 100.466 131.506 132.231 1.00 122.50 ? 595 PHE D O   1 
ATOM   5763 C  CB  . PHE B 2 595 ? 102.635 130.378 134.417 1.00 122.50 ? 595 PHE D CB  1 
ATOM   5764 C  CG  . PHE B 2 595 ? 104.130 130.454 134.531 1.00 122.50 ? 595 PHE D CG  1 
ATOM   5765 C  CD1 . PHE B 2 595 ? 104.923 130.478 133.396 1.00 122.50 ? 595 PHE D CD1 1 
ATOM   5766 C  CD2 . PHE B 2 595 ? 104.743 130.492 135.771 1.00 122.50 ? 595 PHE D CD2 1 
ATOM   5767 C  CE1 . PHE B 2 595 ? 106.299 130.543 133.496 1.00 122.50 ? 595 PHE D CE1 1 
ATOM   5768 C  CE2 . PHE B 2 595 ? 106.119 130.557 135.877 1.00 122.50 ? 595 PHE D CE2 1 
ATOM   5769 C  CZ  . PHE B 2 595 ? 106.898 130.582 134.738 1.00 122.50 ? 595 PHE D CZ  1 
ATOM   5770 N  N   . ARG B 2 596 ? 99.581  131.238 134.289 1.00 130.04 ? 596 ARG D N   1 
ATOM   5771 C  CA  . ARG B 2 596 ? 98.235  131.012 133.767 1.00 130.04 ? 596 ARG D CA  1 
ATOM   5772 C  C   . ARG B 2 596 ? 97.761  132.199 132.935 1.00 130.04 ? 596 ARG D C   1 
ATOM   5773 O  O   . ARG B 2 596 ? 97.338  132.042 131.781 1.00 130.04 ? 596 ARG D O   1 
ATOM   5774 C  CB  . ARG B 2 596 ? 97.259  130.756 134.917 1.00 130.04 ? 596 ARG D CB  1 
ATOM   5775 C  CG  . ARG B 2 596 ? 97.613  129.580 135.803 1.00 130.04 ? 596 ARG D CG  1 
ATOM   5776 C  CD  . ARG B 2 596 ? 96.626  129.439 136.951 1.00 130.04 ? 596 ARG D CD  1 
ATOM   5777 N  NE  . ARG B 2 596 ? 97.000  128.368 137.866 1.00 130.04 ? 596 ARG D NE  1 
ATOM   5778 C  CZ  . ARG B 2 596 ? 96.766  127.080 137.650 1.00 130.04 ? 596 ARG D CZ  1 
ATOM   5779 N  NH1 . ARG B 2 596 ? 96.151  126.664 136.555 1.00 130.04 ? 596 ARG D NH1 1 
ATOM   5780 N  NH2 . ARG B 2 596 ? 97.158  126.189 138.556 1.00 130.04 ? 596 ARG D NH2 1 
ATOM   5781 N  N   . LEU B 2 597 ? 97.838  133.402 133.507 1.00 137.06 ? 597 LEU D N   1 
ATOM   5782 C  CA  . LEU B 2 597 ? 97.338  134.581 132.814 1.00 137.06 ? 597 LEU D CA  1 
ATOM   5783 C  C   . LEU B 2 597 ? 98.229  134.948 131.636 1.00 137.06 ? 597 LEU D C   1 
ATOM   5784 O  O   . LEU B 2 597 ? 97.740  135.458 130.625 1.00 137.06 ? 597 LEU D O   1 
ATOM   5785 C  CB  . LEU B 2 597 ? 97.207  135.755 133.783 1.00 137.06 ? 597 LEU D CB  1 
ATOM   5786 C  CG  . LEU B 2 597 ? 96.190  136.811 133.340 1.00 137.06 ? 597 LEU D CG  1 
ATOM   5787 C  CD1 . LEU B 2 597 ? 94.820  136.178 133.150 1.00 137.06 ? 597 LEU D CD1 1 
ATOM   5788 C  CD2 . LEU B 2 597 ? 96.112  137.959 134.332 1.00 137.06 ? 597 LEU D CD2 1 
ATOM   5789 N  N   . SER B 2 598 ? 99.537  134.688 131.736 1.00 133.48 ? 598 SER D N   1 
ATOM   5790 C  CA  . SER B 2 598 ? 100.409 134.916 130.590 1.00 133.48 ? 598 SER D CA  1 
ATOM   5791 C  C   . SER B 2 598 ? 100.033 134.019 129.420 1.00 133.48 ? 598 SER D C   1 
ATOM   5792 O  O   . SER B 2 598 ? 99.958  134.487 128.277 1.00 133.48 ? 598 SER D O   1 
ATOM   5793 C  CB  . SER B 2 598 ? 101.868 134.689 130.985 1.00 133.48 ? 598 SER D CB  1 
ATOM   5794 O  OG  . SER B 2 598 ? 102.116 133.321 131.256 1.00 133.48 ? 598 SER D OG  1 
ATOM   5795 N  N   . ASP B 2 599 ? 99.785  132.734 129.684 1.00 136.94 ? 599 ASP D N   1 
ATOM   5796 C  CA  . ASP B 2 599 ? 99.380  131.822 128.620 1.00 136.94 ? 599 ASP D CA  1 
ATOM   5797 C  C   . ASP B 2 599 ? 98.039  132.236 128.028 1.00 136.94 ? 599 ASP D C   1 
ATOM   5798 O  O   . ASP B 2 599 ? 97.858  132.229 126.804 1.00 136.94 ? 599 ASP D O   1 
ATOM   5799 C  CB  . ASP B 2 599 ? 99.319  130.390 129.153 1.00 136.94 ? 599 ASP D CB  1 
ATOM   5800 C  CG  . ASP B 2 599 ? 99.184  129.361 128.048 1.00 136.94 ? 599 ASP D CG  1 
ATOM   5801 O  OD1 . ASP B 2 599 ? 99.524  129.682 126.890 1.00 136.94 ? 599 ASP D OD1 1 
ATOM   5802 O  OD2 . ASP B 2 599 ? 98.738  128.231 128.338 1.00 136.94 ? 599 ASP D OD2 1 
ATOM   5803 N  N   . LEU B 2 600 ? 97.087  132.609 128.887 1.00 140.11 ? 600 LEU D N   1 
ATOM   5804 C  CA  . LEU B 2 600 ? 95.779  133.034 128.396 1.00 140.11 ? 600 LEU D CA  1 
ATOM   5805 C  C   . LEU B 2 600 ? 95.897  134.285 127.532 1.00 140.11 ? 600 LEU D C   1 
ATOM   5806 O  O   . LEU B 2 600 ? 95.283  134.377 126.462 1.00 140.11 ? 600 LEU D O   1 
ATOM   5807 C  CB  . LEU B 2 600 ? 94.831  133.275 129.571 1.00 140.11 ? 600 LEU D CB  1 
ATOM   5808 C  CG  . LEU B 2 600 ? 93.453  133.842 129.225 1.00 140.11 ? 600 LEU D CG  1 
ATOM   5809 C  CD1 . LEU B 2 600 ? 92.706  132.905 128.289 1.00 140.11 ? 600 LEU D CD1 1 
ATOM   5810 C  CD2 . LEU B 2 600 ? 92.646  134.100 130.488 1.00 140.11 ? 600 LEU D CD2 1 
ATOM   5811 N  N   . HIS B 2 601 ? 96.692  135.259 127.982 1.00 145.86 ? 601 HIS D N   1 
ATOM   5812 C  CA  . HIS B 2 601 ? 96.864  136.499 127.235 1.00 145.86 ? 601 HIS D CA  1 
ATOM   5813 C  C   . HIS B 2 601 ? 97.541  136.245 125.896 1.00 145.86 ? 601 HIS D C   1 
ATOM   5814 O  O   . HIS B 2 601 ? 97.147  136.815 124.875 1.00 145.86 ? 601 HIS D O   1 
ATOM   5815 C  CB  . HIS B 2 601 ? 97.666  137.500 128.068 1.00 145.86 ? 601 HIS D CB  1 
ATOM   5816 C  CG  . HIS B 2 601 ? 98.251  138.622 127.268 1.00 145.86 ? 601 HIS D CG  1 
ATOM   5817 N  ND1 . HIS B 2 601 ? 97.490  139.658 126.772 1.00 145.86 ? 601 HIS D ND1 1 
ATOM   5818 C  CD2 . HIS B 2 601 ? 99.524  138.871 126.880 1.00 145.86 ? 601 HIS D CD2 1 
ATOM   5819 C  CE1 . HIS B 2 601 ? 98.269  140.497 126.112 1.00 145.86 ? 601 HIS D CE1 1 
ATOM   5820 N  NE2 . HIS B 2 601 ? 99.508  140.042 126.162 1.00 145.86 ? 601 HIS D NE2 1 
ATOM   5821 N  N   . ARG B 2 602 ? 98.569  135.393 125.881 1.00 139.03 ? 602 ARG D N   1 
ATOM   5822 C  CA  . ARG B 2 602 ? 99.244  135.082 124.624 1.00 139.03 ? 602 ARG D CA  1 
ATOM   5823 C  C   . ARG B 2 602 ? 98.307  134.371 123.655 1.00 139.03 ? 602 ARG D C   1 
ATOM   5824 O  O   . ARG B 2 602 ? 98.283  134.684 122.456 1.00 139.03 ? 602 ARG D O   1 
ATOM   5825 C  CB  . ARG B 2 602 ? 100.488 134.236 124.892 1.00 139.03 ? 602 ARG D CB  1 
ATOM   5826 C  CG  . ARG B 2 602 ? 101.659 135.025 125.454 1.00 139.03 ? 602 ARG D CG  1 
ATOM   5827 C  CD  . ARG B 2 602 ? 102.753 134.108 125.975 1.00 139.03 ? 602 ARG D CD  1 
ATOM   5828 N  NE  . ARG B 2 602 ? 102.427 133.538 127.277 1.00 139.03 ? 602 ARG D NE  1 
ATOM   5829 C  CZ  . ARG B 2 602 ? 102.985 132.443 127.774 1.00 139.03 ? 602 ARG D CZ  1 
ATOM   5830 N  NH1 . ARG B 2 602 ? 103.894 131.762 127.096 1.00 139.03 ? 602 ARG D NH1 1 
ATOM   5831 N  NH2 . ARG B 2 602 ? 102.625 132.021 128.982 1.00 139.03 ? 602 ARG D NH2 1 
ATOM   5832 N  N   . LYS B 2 603 ? 97.522  133.414 124.157 1.00 138.05 ? 603 LYS D N   1 
ATOM   5833 C  CA  . LYS B 2 603 ? 96.582  132.703 123.298 1.00 138.05 ? 603 LYS D CA  1 
ATOM   5834 C  C   . LYS B 2 603 ? 95.544  133.657 122.722 1.00 138.05 ? 603 LYS D C   1 
ATOM   5835 O  O   . LYS B 2 603 ? 95.232  133.606 121.527 1.00 138.05 ? 603 LYS D O   1 
ATOM   5836 C  CB  . LYS B 2 603 ? 95.911  131.572 124.080 1.00 138.05 ? 603 LYS D CB  1 
ATOM   5837 C  CG  . LYS B 2 603 ? 95.269  130.497 123.211 1.00 138.05 ? 603 LYS D CG  1 
ATOM   5838 C  CD  . LYS B 2 603 ? 93.806  130.800 122.925 1.00 138.05 ? 603 LYS D CD  1 
ATOM   5839 C  CE  . LYS B 2 603 ? 93.158  129.683 122.126 1.00 138.05 ? 603 LYS D CE  1 
ATOM   5840 N  NZ  . LYS B 2 603 ? 91.711  129.941 121.891 1.00 138.05 ? 603 LYS D NZ  1 
ATOM   5841 N  N   . GLU B 2 604 ? 95.002  134.545 123.560 1.00 147.56 ? 604 GLU D N   1 
ATOM   5842 C  CA  . GLU B 2 604 ? 94.013  135.502 123.073 1.00 147.56 ? 604 GLU D CA  1 
ATOM   5843 C  C   . GLU B 2 604 ? 94.628  136.469 122.068 1.00 147.56 ? 604 GLU D C   1 
ATOM   5844 O  O   . GLU B 2 604 ? 93.997  136.814 121.062 1.00 147.56 ? 604 GLU D O   1 
ATOM   5845 C  CB  . GLU B 2 604 ? 93.395  136.263 124.245 1.00 147.56 ? 604 GLU D CB  1 
ATOM   5846 C  CG  . GLU B 2 604 ? 92.158  137.063 123.873 1.00 147.56 ? 604 GLU D CG  1 
ATOM   5847 C  CD  . GLU B 2 604 ? 91.031  136.188 123.358 1.00 147.56 ? 604 GLU D CD  1 
ATOM   5848 O  OE1 . GLU B 2 604 ? 90.888  135.048 123.849 1.00 147.56 ? 604 GLU D OE1 1 
ATOM   5849 O  OE2 . GLU B 2 604 ? 90.289  136.638 122.460 1.00 147.56 ? 604 GLU D OE2 1 
ATOM   5850 N  N   . GLN B 2 605 ? 95.860  136.914 122.322 1.00 143.53 ? 605 GLN D N   1 
ATOM   5851 C  CA  . GLN B 2 605 ? 96.523  137.849 121.421 1.00 143.53 ? 605 GLN D CA  1 
ATOM   5852 C  C   . GLN B 2 605 ? 96.759  137.223 120.053 1.00 143.53 ? 605 GLN D C   1 
ATOM   5853 O  O   . GLN B 2 605 ? 96.550  137.867 119.019 1.00 143.53 ? 605 GLN D O   1 
ATOM   5854 C  CB  . GLN B 2 605 ? 97.843  138.317 122.037 1.00 143.53 ? 605 GLN D CB  1 
ATOM   5855 C  CG  . GLN B 2 605 ? 98.612  139.315 121.188 1.00 143.53 ? 605 GLN D CG  1 
ATOM   5856 C  CD  . GLN B 2 605 ? 99.896  139.774 121.852 1.00 143.53 ? 605 GLN D CD  1 
ATOM   5857 O  OE1 . GLN B 2 605 ? 100.337 139.192 122.844 1.00 143.53 ? 605 GLN D OE1 1 
ATOM   5858 N  NE2 . GLN B 2 605 ? 100.502 140.822 121.308 1.00 143.53 ? 605 GLN D NE2 1 
ATOM   5859 N  N   . GLN B 2 606 ? 97.199  135.962 120.025 1.00 146.61 ? 606 GLN D N   1 
ATOM   5860 C  CA  . GLN B 2 606 ? 97.423  135.314 118.736 1.00 146.61 ? 606 GLN D CA  1 
ATOM   5861 C  C   . GLN B 2 606 ? 96.102  134.991 118.043 1.00 146.61 ? 606 GLN D C   1 
ATOM   5862 O  O   . GLN B 2 606 ? 95.996  135.108 116.815 1.00 146.61 ? 606 GLN D O   1 
ATOM   5863 C  CB  . GLN B 2 606 ? 98.283  134.059 118.908 1.00 146.61 ? 606 GLN D CB  1 
ATOM   5864 C  CG  . GLN B 2 606 ? 97.621  132.902 119.634 1.00 146.61 ? 606 GLN D CG  1 
ATOM   5865 C  CD  . GLN B 2 606 ? 98.472  131.647 119.621 1.00 146.61 ? 606 GLN D CD  1 
ATOM   5866 O  OE1 . GLN B 2 606 ? 99.598  131.652 119.125 1.00 146.61 ? 606 GLN D OE1 1 
ATOM   5867 N  NE2 . GLN B 2 606 ? 97.935  130.562 120.167 1.00 146.61 ? 606 GLN D NE2 1 
ATOM   5868 N  N   . ASP B 2 607 ? 95.076  134.608 118.809 1.00 143.38 ? 607 ASP D N   1 
ATOM   5869 C  CA  . ASP B 2 607 ? 93.781  134.298 118.213 1.00 143.38 ? 607 ASP D CA  1 
ATOM   5870 C  C   . ASP B 2 607 ? 93.156  135.537 117.584 1.00 143.38 ? 607 ASP D C   1 
ATOM   5871 O  O   . ASP B 2 607 ? 92.577  135.467 116.494 1.00 143.38 ? 607 ASP D O   1 
ATOM   5872 C  CB  . ASP B 2 607 ? 92.850  133.698 119.267 1.00 143.38 ? 607 ASP D CB  1 
ATOM   5873 C  CG  . ASP B 2 607 ? 91.653  132.996 118.656 1.00 143.38 ? 607 ASP D CG  1 
ATOM   5874 O  OD1 . ASP B 2 607 ? 91.629  132.825 117.419 1.00 143.38 ? 607 ASP D OD1 1 
ATOM   5875 O  OD2 . ASP B 2 607 ? 90.737  132.613 119.413 1.00 143.38 ? 607 ASP D OD2 1 
ATOM   5876 N  N   . GLU B 2 608 ? 93.256  136.683 118.262 1.00 143.95 ? 608 GLU D N   1 
ATOM   5877 C  CA  . GLU B 2 608 ? 92.699  137.915 117.712 1.00 143.95 ? 608 GLU D CA  1 
ATOM   5878 C  C   . GLU B 2 608 ? 93.409  138.312 116.425 1.00 143.95 ? 608 GLU D C   1 
ATOM   5879 O  O   . GLU B 2 608 ? 92.766  138.731 115.455 1.00 143.95 ? 608 GLU D O   1 
ATOM   5880 C  CB  . GLU B 2 608 ? 92.785  139.038 118.746 1.00 143.95 ? 608 GLU D CB  1 
ATOM   5881 C  CG  . GLU B 2 608 ? 92.340  140.401 118.233 1.00 143.95 ? 608 GLU D CG  1 
ATOM   5882 C  CD  . GLU B 2 608 ? 90.838  140.493 118.019 1.00 143.95 ? 608 GLU D CD  1 
ATOM   5883 O  OE1 . GLU B 2 608 ? 90.111  139.572 118.447 1.00 143.95 ? 608 GLU D OE1 1 
ATOM   5884 O  OE2 . GLU B 2 608 ? 90.385  141.491 117.421 1.00 143.95 ? 608 GLU D OE2 1 
ATOM   5885 N  N   . ASN B 2 609 ? 94.736  138.182 116.395 1.00 142.32 ? 609 ASN D N   1 
ATOM   5886 C  CA  . ASN B 2 609 ? 95.497  138.475 115.188 1.00 142.32 ? 609 ASN D CA  1 
ATOM   5887 C  C   . ASN B 2 609 ? 95.181  137.516 114.048 1.00 142.32 ? 609 ASN D C   1 
ATOM   5888 O  O   . ASN B 2 609 ? 95.216  137.934 112.886 1.00 142.32 ? 609 ASN D O   1 
ATOM   5889 C  CB  . ASN B 2 609 ? 96.996  138.443 115.493 1.00 142.32 ? 609 ASN D CB  1 
ATOM   5890 C  CG  . ASN B 2 609 ? 97.498  139.748 116.079 1.00 142.32 ? 609 ASN D CG  1 
ATOM   5891 O  OD1 . ASN B 2 609 ? 97.808  140.691 115.351 1.00 142.32 ? 609 ASN D OD1 1 
ATOM   5892 N  ND2 . ASN B 2 609 ? 97.578  139.810 117.403 1.00 142.32 ? 609 ASN D ND2 1 
ATOM   5893 N  N   . ILE B 2 610 ? 94.890  136.250 114.344 1.00 137.82 ? 610 ILE D N   1 
ATOM   5894 C  CA  . ILE B 2 610 ? 94.485  135.324 113.290 1.00 137.82 ? 610 ILE D CA  1 
ATOM   5895 C  C   . ILE B 2 610 ? 93.095  135.672 112.767 1.00 137.82 ? 610 ILE D C   1 
ATOM   5896 O  O   . ILE B 2 610 ? 92.860  135.690 111.553 1.00 137.82 ? 610 ILE D O   1 
ATOM   5897 C  CB  . ILE B 2 610 ? 94.554  133.870 113.793 1.00 137.82 ? 610 ILE D CB  1 
ATOM   5898 C  CG1 . ILE B 2 610 ? 95.994  133.495 114.149 1.00 137.82 ? 610 ILE D CG1 1 
ATOM   5899 C  CG2 . ILE B 2 610 ? 93.997  132.914 112.748 1.00 137.82 ? 610 ILE D CG2 1 
ATOM   5900 C  CD1 . ILE B 2 610 ? 96.985  133.740 113.031 1.00 137.82 ? 610 ILE D CD1 1 
ATOM   5901 N  N   . ARG B 2 611 ? 92.154  135.962 113.670 1.00 143.17 ? 611 ARG D N   1 
ATOM   5902 C  CA  . ARG B 2 611 ? 90.772  136.195 113.259 1.00 143.17 ? 611 ARG D CA  1 
ATOM   5903 C  C   . ARG B 2 611 ? 90.554  137.573 112.646 1.00 143.17 ? 611 ARG D C   1 
ATOM   5904 O  O   . ARG B 2 611 ? 89.543  137.775 111.964 1.00 143.17 ? 611 ARG D O   1 
ATOM   5905 C  CB  . ARG B 2 611 ? 89.823  136.015 114.446 1.00 143.17 ? 611 ARG D CB  1 
ATOM   5906 C  CG  . ARG B 2 611 ? 89.906  134.663 115.138 1.00 143.17 ? 611 ARG D CG  1 
ATOM   5907 C  CD  . ARG B 2 611 ? 89.870  133.512 114.146 1.00 143.17 ? 611 ARG D CD  1 
ATOM   5908 N  NE  . ARG B 2 611 ? 90.348  132.272 114.746 1.00 143.17 ? 611 ARG D NE  1 
ATOM   5909 C  CZ  . ARG B 2 611 ? 90.306  131.087 114.152 1.00 143.17 ? 611 ARG D CZ  1 
ATOM   5910 N  NH1 . ARG B 2 611 ? 89.812  130.941 112.934 1.00 143.17 ? 611 ARG D NH1 1 
ATOM   5911 N  NH2 . ARG B 2 611 ? 90.771  130.021 114.798 1.00 143.17 ? 611 ARG D NH2 1 
ATOM   5912 N  N   . ARG B 2 612 ? 91.464  138.524 112.868 1.00 141.15 ? 612 ARG D N   1 
ATOM   5913 C  CA  . ARG B 2 612 ? 91.249  139.881 112.376 1.00 141.15 ? 612 ARG D CA  1 
ATOM   5914 C  C   . ARG B 2 612 ? 91.331  139.989 110.859 1.00 141.15 ? 612 ARG D C   1 
ATOM   5915 O  O   . ARG B 2 612 ? 90.973  141.039 110.314 1.00 141.15 ? 612 ARG D O   1 
ATOM   5916 C  CB  . ARG B 2 612 ? 92.257  140.843 113.009 1.00 141.15 ? 612 ARG D CB  1 
ATOM   5917 C  CG  . ARG B 2 612 ? 93.681  140.671 112.512 1.00 141.15 ? 612 ARG D CG  1 
ATOM   5918 C  CD  . ARG B 2 612 ? 94.611  141.703 113.130 1.00 141.15 ? 612 ARG D CD  1 
ATOM   5919 N  NE  . ARG B 2 612 ? 94.373  143.041 112.599 1.00 141.15 ? 612 ARG D NE  1 
ATOM   5920 C  CZ  . ARG B 2 612 ? 94.852  143.486 111.446 1.00 141.15 ? 612 ARG D CZ  1 
ATOM   5921 N  NH1 . ARG B 2 612 ? 95.603  142.723 110.668 1.00 141.15 ? 612 ARG D NH1 1 
ATOM   5922 N  NH2 . ARG B 2 612 ? 94.571  144.728 111.062 1.00 141.15 ? 612 ARG D NH2 1 
ATOM   5923 N  N   . ARG B 2 613 ? 91.794  138.949 110.170 1.00 125.46 ? 613 ARG D N   1 
ATOM   5924 C  CA  . ARG B 2 613 ? 91.896  138.973 108.714 1.00 125.46 ? 613 ARG D CA  1 
ATOM   5925 C  C   . ARG B 2 613 ? 90.524  139.117 108.061 1.00 125.46 ? 613 ARG D C   1 
ATOM   5926 O  O   . ARG B 2 613 ? 90.409  139.577 106.925 1.00 125.46 ? 613 ARG D O   1 
ATOM   5927 C  CB  . ARG B 2 613 ? 92.583  137.705 108.203 1.00 125.46 ? 613 ARG D CB  1 
ATOM   5928 C  CG  . ARG B 2 613 ? 94.022  137.543 108.662 1.00 125.46 ? 613 ARG D CG  1 
ATOM   5929 C  CD  . ARG B 2 613 ? 94.609  136.239 108.149 1.00 125.46 ? 613 ARG D CD  1 
ATOM   5930 N  NE  . ARG B 2 613 ? 95.867  135.904 108.806 1.00 125.46 ? 613 ARG D NE  1 
ATOM   5931 C  CZ  . ARG B 2 613 ? 96.460  134.721 108.725 1.00 125.46 ? 613 ARG D CZ  1 
ATOM   5932 N  NH1 . ARG B 2 613 ? 95.937  133.732 108.018 1.00 125.46 ? 613 ARG D NH1 1 
ATOM   5933 N  NH2 . ARG B 2 613 ? 97.606  134.524 109.370 1.00 125.46 ? 613 ARG D NH2 1 
ATOM   5934 N  N   . HIS B 2 644 ? 85.995  100.369 111.552 1.00 126.11 ? 644 HIS D N   1 
ATOM   5935 C  CA  . HIS B 2 644 ? 85.344  99.075  111.716 1.00 126.11 ? 644 HIS D CA  1 
ATOM   5936 C  C   . HIS B 2 644 ? 85.968  98.289  112.866 1.00 126.11 ? 644 HIS D C   1 
ATOM   5937 O  O   . HIS B 2 644 ? 86.980  98.701  113.434 1.00 126.11 ? 644 HIS D O   1 
ATOM   5938 C  CB  . HIS B 2 644 ? 85.421  98.264  110.420 1.00 126.11 ? 644 HIS D CB  1 
ATOM   5939 C  CG  . HIS B 2 644 ? 86.818  98.025  109.935 1.00 126.11 ? 644 HIS D CG  1 
ATOM   5940 N  ND1 . HIS B 2 644 ? 87.627  99.037  109.465 1.00 126.11 ? 644 HIS D ND1 1 
ATOM   5941 C  CD2 . HIS B 2 644 ? 87.548  96.889  109.846 1.00 126.11 ? 644 HIS D CD2 1 
ATOM   5942 C  CE1 . HIS B 2 644 ? 88.795  98.535  109.108 1.00 126.11 ? 644 HIS D CE1 1 
ATOM   5943 N  NE2 . HIS B 2 644 ? 88.774  97.233  109.329 1.00 126.11 ? 644 HIS D NE2 1 
ATOM   5944 N  N   . ASP B 2 645 ? 85.353  97.159  113.205 1.00 124.37 ? 645 ASP D N   1 
ATOM   5945 C  CA  . ASP B 2 645 ? 85.860  96.326  114.286 1.00 124.37 ? 645 ASP D CA  1 
ATOM   5946 C  C   . ASP B 2 645 ? 87.200  95.708  113.905 1.00 124.37 ? 645 ASP D C   1 
ATOM   5947 O  O   . ASP B 2 645 ? 87.486  95.459  112.731 1.00 124.37 ? 645 ASP D O   1 
ATOM   5948 C  CB  . ASP B 2 645 ? 84.854  95.226  114.629 1.00 124.37 ? 645 ASP D CB  1 
ATOM   5949 C  CG  . ASP B 2 645 ? 83.620  95.763  115.326 1.00 124.37 ? 645 ASP D CG  1 
ATOM   5950 O  OD1 . ASP B 2 645 ? 83.765  96.643  116.200 1.00 124.37 ? 645 ASP D OD1 1 
ATOM   5951 O  OD2 . ASP B 2 645 ? 82.505  95.304  115.001 1.00 124.37 ? 645 ASP D OD2 1 
ATOM   5952 N  N   . ILE B 2 646 ? 88.030  95.463  114.920 1.00 102.55 ? 646 ILE D N   1 
ATOM   5953 C  CA  . ILE B 2 646 ? 89.346  94.883  114.687 1.00 102.55 ? 646 ILE D CA  1 
ATOM   5954 C  C   . ILE B 2 646 ? 89.198  93.436  114.240 1.00 102.55 ? 646 ILE D C   1 
ATOM   5955 O  O   . ILE B 2 646 ? 88.458  92.649  114.847 1.00 102.55 ? 646 ILE D O   1 
ATOM   5956 C  CB  . ILE B 2 646 ? 90.211  94.990  115.954 1.00 102.55 ? 646 ILE D CB  1 
ATOM   5957 C  CG1 . ILE B 2 646 ? 90.314  96.447  116.407 1.00 102.55 ? 646 ILE D CG1 1 
ATOM   5958 C  CG2 . ILE B 2 646 ? 91.594  94.412  115.703 1.00 102.55 ? 646 ILE D CG2 1 
ATOM   5959 C  CD1 . ILE B 2 646 ? 90.661  96.608  117.870 1.00 102.55 ? 646 ILE D CD1 1 
ATOM   5960 N  N   . ASP B 2 647 ? 89.902  93.078  113.169 1.00 119.99 ? 647 ASP D N   1 
ATOM   5961 C  CA  . ASP B 2 647 ? 89.845  91.728  112.625 1.00 119.99 ? 647 ASP D CA  1 
ATOM   5962 C  C   . ASP B 2 647 ? 91.235  91.291  112.178 1.00 119.99 ? 647 ASP D C   1 
ATOM   5963 O  O   . ASP B 2 647 ? 91.773  91.833  111.204 1.00 119.99 ? 647 ASP D O   1 
ATOM   5964 C  CB  . ASP B 2 647 ? 88.857  91.662  111.458 1.00 119.99 ? 647 ASP D CB  1 
ATOM   5965 C  CG  . ASP B 2 647 ? 88.469  90.240  111.097 1.00 119.99 ? 647 ASP D CG  1 
ATOM   5966 O  OD1 . ASP B 2 647 ? 89.012  89.295  111.706 1.00 119.99 ? 647 ASP D OD1 1 
ATOM   5967 O  OD2 . ASP B 2 647 ? 87.618  90.067  110.200 1.00 119.99 ? 647 ASP D OD2 1 
ATOM   5968 N  N   . PRO B 2 648 ? 91.851  90.323  112.865 1.00 109.75 ? 648 PRO D N   1 
ATOM   5969 C  CA  . PRO B 2 648 ? 93.183  89.855  112.449 1.00 109.75 ? 648 PRO D CA  1 
ATOM   5970 C  C   . PRO B 2 648 ? 93.202  89.192  111.083 1.00 109.75 ? 648 PRO D C   1 
ATOM   5971 O  O   . PRO B 2 648 ? 94.263  89.165  110.446 1.00 109.75 ? 648 PRO D O   1 
ATOM   5972 C  CB  . PRO B 2 648 ? 93.564  88.862  113.553 1.00 109.75 ? 648 PRO D CB  1 
ATOM   5973 C  CG  . PRO B 2 648 ? 92.257  88.359  114.060 1.00 109.75 ? 648 PRO D CG  1 
ATOM   5974 C  CD  . PRO B 2 648 ? 91.307  89.525  113.976 1.00 109.75 ? 648 PRO D CD  1 
ATOM   5975 N  N   . THR B 2 649 ? 92.073  88.658  110.615 1.00 116.34 ? 649 THR D N   1 
ATOM   5976 C  CA  . THR B 2 649 ? 92.008  88.051  109.293 1.00 116.34 ? 649 THR D CA  1 
ATOM   5977 C  C   . THR B 2 649 ? 91.961  89.081  108.173 1.00 116.34 ? 649 THR D C   1 
ATOM   5978 O  O   . THR B 2 649 ? 92.154  88.716  107.008 1.00 116.34 ? 649 THR D O   1 
ATOM   5979 C  CB  . THR B 2 649 ? 90.787  87.134  109.193 1.00 116.34 ? 649 THR D CB  1 
ATOM   5980 O  OG1 . THR B 2 649 ? 89.594  87.926  109.138 1.00 116.34 ? 649 THR D OG1 1 
ATOM   5981 C  CG2 . THR B 2 649 ? 90.719  86.207  110.397 1.00 116.34 ? 649 THR D CG2 1 
ATOM   5982 N  N   . ASP B 2 650 ? 91.712  90.349  108.495 1.00 112.79 ? 650 ASP D N   1 
ATOM   5983 C  CA  . ASP B 2 650 ? 91.683  91.409  107.495 1.00 112.79 ? 650 ASP D CA  1 
ATOM   5984 C  C   . ASP B 2 650 ? 93.084  91.966  107.275 1.00 112.79 ? 650 ASP D C   1 
ATOM   5985 O  O   . ASP B 2 650 ? 93.341  93.142  107.556 1.00 112.79 ? 650 ASP D O   1 
ATOM   5986 C  CB  . ASP B 2 650 ? 90.722  92.519  107.927 1.00 112.79 ? 650 ASP D CB  1 
ATOM   5987 C  CG  . ASP B 2 650 ? 90.424  93.501  106.813 1.00 112.79 ? 650 ASP D CG  1 
ATOM   5988 O  OD1 . ASP B 2 650 ? 90.842  93.247  105.664 1.00 112.79 ? 650 ASP D OD1 1 
ATOM   5989 O  OD2 . ASP B 2 650 ? 89.775  94.532  107.091 1.00 112.79 ? 650 ASP D OD2 1 
ATOM   5990 N  N   . CYS B 2 651 ? 93.995  91.133  106.778 1.00 105.79 ? 651 CYS D N   1 
ATOM   5991 C  CA  . CYS B 2 651 ? 95.376  91.541  106.577 1.00 105.79 ? 651 CYS D CA  1 
ATOM   5992 C  C   . CYS B 2 651 ? 96.017  90.682  105.497 1.00 105.79 ? 651 CYS D C   1 
ATOM   5993 O  O   . CYS B 2 651 ? 95.533  89.597  105.164 1.00 105.79 ? 651 CYS D O   1 
ATOM   5994 C  CB  . CYS B 2 651 ? 96.188  91.441  107.876 1.00 105.79 ? 651 CYS D CB  1 
ATOM   5995 S  SG  . CYS B 2 651 ? 96.649  89.757  108.341 1.00 105.79 ? 651 CYS D SG  1 
ATOM   5996 N  N   . GLU B 2 652 ? 97.120  91.190  104.953 1.00 89.58  ? 652 GLU D N   1 
ATOM   5997 C  CA  . GLU B 2 652 ? 97.948  90.467  104.000 1.00 89.58  ? 652 GLU D CA  1 
ATOM   5998 C  C   . GLU B 2 652 ? 99.352  90.337  104.570 1.00 89.58  ? 652 GLU D C   1 
ATOM   5999 O  O   . GLU B 2 652 ? 99.871  91.266  105.195 1.00 89.58  ? 652 GLU D O   1 
ATOM   6000 C  CB  . GLU B 2 652 ? 97.992  91.178  102.642 1.00 89.58  ? 652 GLU D CB  1 
ATOM   6001 C  CG  . GLU B 2 652 ? 96.657  91.214  101.916 1.00 89.58  ? 652 GLU D CG  1 
ATOM   6002 C  CD  . GLU B 2 652 ? 96.769  91.795  100.520 1.00 89.58  ? 652 GLU D CD  1 
ATOM   6003 O  OE1 . GLU B 2 652 ? 97.505  92.788  100.345 1.00 89.58  ? 652 GLU D OE1 1 
ATOM   6004 O  OE2 . GLU B 2 652 ? 96.119  91.258  99.598  1.00 89.58  ? 652 GLU D OE2 1 
ATOM   6005 N  N   . SER B 2 653 ? 99.969  89.178  104.352 1.00 75.07  ? 653 SER D N   1 
ATOM   6006 C  CA  . SER B 2 653 ? 101.231 88.878  105.012 1.00 75.07  ? 653 SER D CA  1 
ATOM   6007 C  C   . SER B 2 653 ? 102.217 88.303  104.007 1.00 75.07  ? 653 SER D C   1 
ATOM   6008 O  O   . SER B 2 653 ? 101.837 87.818  102.939 1.00 75.07  ? 653 SER D O   1 
ATOM   6009 C  CB  . SER B 2 653 ? 101.031 87.906  106.179 1.00 75.07  ? 653 SER D CB  1 
ATOM   6010 O  OG  . SER B 2 653 ? 102.261 87.622  106.822 1.00 75.07  ? 653 SER D OG  1 
ATOM   6011 N  N   . LYS B 2 654 ? 103.496 88.369  104.373 1.00 65.53  ? 654 LYS D N   1 
ATOM   6012 C  CA  . LYS B 2 654 ? 104.575 87.824  103.565 1.00 65.53  ? 654 LYS D CA  1 
ATOM   6013 C  C   . LYS B 2 654 ? 105.748 87.489  104.475 1.00 65.53  ? 654 LYS D C   1 
ATOM   6014 O  O   . LYS B 2 654 ? 106.040 88.218  105.426 1.00 65.53  ? 654 LYS D O   1 
ATOM   6015 C  CB  . LYS B 2 654 ? 105.010 88.806  102.469 1.00 65.53  ? 654 LYS D CB  1 
ATOM   6016 C  CG  . LYS B 2 654 ? 106.154 88.310  101.599 1.00 65.53  ? 654 LYS D CG  1 
ATOM   6017 C  CD  . LYS B 2 654 ? 105.756 87.070  100.816 1.00 65.53  ? 654 LYS D CD  1 
ATOM   6018 C  CE  . LYS B 2 654 ? 106.888 86.592  99.923  1.00 65.53  ? 654 LYS D CE  1 
ATOM   6019 N  NZ  . LYS B 2 654 ? 106.504 85.385  99.142  1.00 65.53  ? 654 LYS D NZ  1 
ATOM   6020 N  N   . VAL B 2 655 ? 106.415 86.378  104.175 1.00 68.56  ? 655 VAL D N   1 
ATOM   6021 C  CA  . VAL B 2 655 ? 107.582 85.921  104.921 1.00 68.56  ? 655 VAL D CA  1 
ATOM   6022 C  C   . VAL B 2 655 ? 108.798 86.037  104.013 1.00 68.56  ? 655 VAL D C   1 
ATOM   6023 O  O   . VAL B 2 655 ? 108.770 85.578  102.865 1.00 68.56  ? 655 VAL D O   1 
ATOM   6024 C  CB  . VAL B 2 655 ? 107.404 84.478  105.424 1.00 68.56  ? 655 VAL D CB  1 
ATOM   6025 C  CG1 . VAL B 2 655 ? 108.520 84.113  106.391 1.00 68.56  ? 655 VAL D CG1 1 
ATOM   6026 C  CG2 . VAL B 2 655 ? 106.044 84.310  106.082 1.00 68.56  ? 655 VAL D CG2 1 
ATOM   6027 N  N   . ILE B 2 656 ? 109.863 86.649  104.526 1.00 78.29  ? 656 ILE D N   1 
ATOM   6028 C  CA  . ILE B 2 656 ? 111.045 86.969  103.735 1.00 78.29  ? 656 ILE D CA  1 
ATOM   6029 C  C   . ILE B 2 656 ? 112.244 86.232  104.315 1.00 78.29  ? 656 ILE D C   1 
ATOM   6030 O  O   . ILE B 2 656 ? 112.427 86.197  105.536 1.00 78.29  ? 656 ILE D O   1 
ATOM   6031 C  CB  . ILE B 2 656 ? 111.310 88.486  103.697 1.00 78.29  ? 656 ILE D CB  1 
ATOM   6032 C  CG1 . ILE B 2 656 ? 110.041 89.236  103.290 1.00 78.29  ? 656 ILE D CG1 1 
ATOM   6033 C  CG2 . ILE B 2 656 ? 112.442 88.804  102.736 1.00 78.29  ? 656 ILE D CG2 1 
ATOM   6034 C  CD1 . ILE B 2 656 ? 110.249 90.717  103.081 1.00 78.29  ? 656 ILE D CD1 1 
ATOM   6035 N  N   . ASP B 2 657 ? 113.053 85.644  103.437 1.00 105.88 ? 657 ASP D N   1 
ATOM   6036 C  CA  . ASP B 2 657 ? 114.279 84.985  103.854 1.00 105.88 ? 657 ASP D CA  1 
ATOM   6037 C  C   . ASP B 2 657 ? 115.265 86.015  104.408 1.00 105.88 ? 657 ASP D C   1 
ATOM   6038 O  O   . ASP B 2 657 ? 115.281 87.168  103.969 1.00 105.88 ? 657 ASP D O   1 
ATOM   6039 C  CB  . ASP B 2 657 ? 114.894 84.236  102.670 1.00 105.88 ? 657 ASP D CB  1 
ATOM   6040 C  CG  . ASP B 2 657 ? 116.224 83.588  103.004 1.00 105.88 ? 657 ASP D CG  1 
ATOM   6041 O  OD1 . ASP B 2 657 ? 117.261 84.281  102.945 1.00 105.88 ? 657 ASP D OD1 1 
ATOM   6042 O  OD2 . ASP B 2 657 ? 116.232 82.381  103.327 1.00 105.88 ? 657 ASP D OD2 1 
ATOM   6043 N  N   . PRO B 2 658 ? 116.083 85.630  105.393 1.00 94.33  ? 658 PRO D N   1 
ATOM   6044 C  CA  . PRO B 2 658 ? 117.073 86.575  105.938 1.00 94.33  ? 658 PRO D CA  1 
ATOM   6045 C  C   . PRO B 2 658 ? 118.023 87.145  104.900 1.00 94.33  ? 658 PRO D C   1 
ATOM   6046 O  O   . PRO B 2 658 ? 118.383 88.324  104.998 1.00 94.33  ? 658 PRO D O   1 
ATOM   6047 C  CB  . PRO B 2 658 ? 117.827 85.734  106.981 1.00 94.33  ? 658 PRO D CB  1 
ATOM   6048 C  CG  . PRO B 2 658 ? 117.439 84.303  106.701 1.00 94.33  ? 658 PRO D CG  1 
ATOM   6049 C  CD  . PRO B 2 658 ? 116.049 84.380  106.167 1.00 94.33  ? 658 PRO D CD  1 
ATOM   6050 N  N   . LYS B 2 659 ? 118.444 86.353  103.913 1.00 112.64 ? 659 LYS D N   1 
ATOM   6051 C  CA  . LYS B 2 659 ? 119.350 86.828  102.879 1.00 112.64 ? 659 LYS D CA  1 
ATOM   6052 C  C   . LYS B 2 659 ? 118.644 87.332  101.630 1.00 112.64 ? 659 LYS D C   1 
ATOM   6053 O  O   . LYS B 2 659 ? 119.282 88.005  100.812 1.00 112.64 ? 659 LYS D O   1 
ATOM   6054 C  CB  . LYS B 2 659 ? 120.340 85.720  102.485 1.00 112.64 ? 659 LYS D CB  1 
ATOM   6055 C  CG  . LYS B 2 659 ? 121.295 85.331  103.601 1.00 112.64 ? 659 LYS D CG  1 
ATOM   6056 C  CD  . LYS B 2 659 ? 122.142 86.517  104.035 1.00 112.64 ? 659 LYS D CD  1 
ATOM   6057 C  CE  . LYS B 2 659 ? 123.239 86.094  104.997 1.00 112.64 ? 659 LYS D CE  1 
ATOM   6058 N  NZ  . LYS B 2 659 ? 122.692 85.710  106.327 1.00 112.64 ? 659 LYS D NZ  1 
ATOM   6059 N  N   . LYS B 2 660 ? 117.356 87.032  101.455 1.00 118.25 ? 660 LYS D N   1 
ATOM   6060 C  CA  . LYS B 2 660 ? 116.607 87.548  100.317 1.00 118.25 ? 660 LYS D CA  1 
ATOM   6061 C  C   . LYS B 2 660 ? 116.184 88.998  100.509 1.00 118.25 ? 660 LYS D C   1 
ATOM   6062 O  O   . LYS B 2 660 ? 115.729 89.630  99.549  1.00 118.25 ? 660 LYS D O   1 
ATOM   6063 C  CB  . LYS B 2 660 ? 115.374 86.677  100.063 1.00 118.25 ? 660 LYS D CB  1 
ATOM   6064 C  CG  . LYS B 2 660 ? 114.888 86.673  98.623  1.00 118.25 ? 660 LYS D CG  1 
ATOM   6065 C  CD  . LYS B 2 660 ? 113.772 85.660  98.424  1.00 118.25 ? 660 LYS D CD  1 
ATOM   6066 C  CE  . LYS B 2 660 ? 113.380 85.548  96.961  1.00 118.25 ? 660 LYS D CE  1 
ATOM   6067 N  NZ  . LYS B 2 660 ? 112.709 86.784  96.472  1.00 118.25 ? 660 LYS D NZ  1 
ATOM   6068 N  N   . SER B 2 661 ? 116.325 89.535  101.716 1.00 119.96 ? 661 SER D N   1 
ATOM   6069 C  CA  . SER B 2 661 ? 115.956 90.917  101.997 1.00 119.96 ? 661 SER D CA  1 
ATOM   6070 C  C   . SER B 2 661 ? 117.180 91.827  101.973 1.00 119.96 ? 661 SER D C   1 
ATOM   6071 O  O   . SER B 2 661 ? 117.061 93.052  101.994 1.00 119.96 ? 661 SER D O   1 
ATOM   6072 C  CB  . SER B 2 661 ? 115.253 91.018  103.352 1.00 119.96 ? 661 SER D CB  1 
ATOM   6073 O  OG  . SER B 2 661 ? 115.931 90.256  104.335 1.00 119.96 ? 661 SER D OG  1 
ATOM   6074 O  OXT . SER B 2 661 ? 118.318 91.357  101.935 1.00 119.96 ? 661 SER D OXT 1 
HETATM 6075 FE FE  . FE  C 3 .   ? 108.464 105.233 117.896 1.00 43.86  ? 701 FE  D FE  1 
HETATM 6076 ZN ZN  . ZN  D 4 .   ? 111.271 105.525 119.378 1.00 42.93  ? 702 ZN  D ZN  1 
# 
