data_8JEI
# 
_entry.id   8JEI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8JEI         pdb_00008jei 10.2210/pdb8jei/pdb 
WWPDB D_1300037718 ?            ?                   
EMDB  EMD-36189    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8JEI 
_pdbx_database_status.recvd_initial_deposition_date   2023-05-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM Structure of the compuond 5c-HCAR3-Gi complex' 
_pdbx_database_related.db_id          EMD-36189 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yefang20220804@163.com 
_pdbx_contact_author.name_first         Ye 
_pdbx_contact_author.name_last          Fang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0030-5739 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fang, Y.' 1 ? 
'Pan, X.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            43 
_citation.language                  ? 
_citation.page_first                114895 
_citation.page_last                 114895 
_citation.title                     'Structural basis for ligand recognition of the human hydroxycarboxylic acid receptor HCAR3.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2024.114895 
_citation.pdbx_database_id_PubMed   39427321 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ye, F.'    1  ? 
primary 'Pan, X.'   2  ? 
primary 'Zhang, Z.' 3  ? 
primary 'Xiang, X.' 4  ? 
primary 'Li, X.'    5  ? 
primary 'Zhang, B.' 6  ? 
primary 'Ning, P.'  7  ? 
primary 'Liu, A.'   8  ? 
primary 'Wang, Q.'  9  ? 
primary 'Gong, K.'  10 ? 
primary 'Li, J.'    11 ? 
primary 'Zhu, L.'   12 ? 
primary 'Qian, C.'  13 ? 
primary 'Chen, G.'  14 ? 
primary 'Du, Y.'    15 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'           40153.672 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  37069.543 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 6218.162  1 ? ? ? ? 
4 polymer     man scFv16                                                              26337.307 1 ? ? ? ? 
5 polymer     man 'Hydroxycarboxylic acid receptor 3'                                 44532.301 1 ? ? ? ? 
6 non-polymer syn '3-nitro-4-(propylamino)benzoic acid'                               224.213   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein' 
3 'G gamma-I' 
5 
;G-protein coupled receptor 109B,G-protein coupled receptor HM74,G-protein coupled receptor HM74B,Niacin receptor 2,Nicotinic acid receptor 2
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
C ? 
2 'polypeptide(L)' no no 
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE 
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE G ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLEL
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLEL
;
S ? 
5 'polypeptide(L)' no no 
;MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICL
PFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTV
HLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGE
PDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGPTSNNHSKKGHCHQEPASLEKQLGCCIE
;
;MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICL
PFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTV
HLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGE
PDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGPTSNNHSKKGHCHQEPASLEKQLGCCIE
;
A ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '3-nitro-4-(propylamino)benzoic acid' 
_pdbx_entity_nonpoly.comp_id     CW3 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   THR n 
1 2   LEU n 
1 3   SER n 
1 4   ALA n 
1 5   GLU n 
1 6   ASP n 
1 7   LYS n 
1 8   ALA n 
1 9   ALA n 
1 10  VAL n 
1 11  GLU n 
1 12  ARG n 
1 13  SER n 
1 14  LYS n 
1 15  MET n 
1 16  ILE n 
1 17  ASP n 
1 18  ARG n 
1 19  ASN n 
1 20  LEU n 
1 21  ARG n 
1 22  GLU n 
1 23  ASP n 
1 24  GLY n 
1 25  GLU n 
1 26  LYS n 
1 27  ALA n 
1 28  ALA n 
1 29  ARG n 
1 30  GLU n 
1 31  VAL n 
1 32  LYS n 
1 33  LEU n 
1 34  LEU n 
1 35  LEU n 
1 36  LEU n 
1 37  GLY n 
1 38  ALA n 
1 39  GLY n 
1 40  GLU n 
1 41  SER n 
1 42  GLY n 
1 43  LYS n 
1 44  SER n 
1 45  THR n 
1 46  ILE n 
1 47  VAL n 
1 48  LYS n 
1 49  GLN n 
1 50  MET n 
1 51  LYS n 
1 52  ILE n 
1 53  ILE n 
1 54  HIS n 
1 55  GLU n 
1 56  ALA n 
1 57  GLY n 
1 58  TYR n 
1 59  SER n 
1 60  GLU n 
1 61  GLU n 
1 62  GLU n 
1 63  CYS n 
1 64  LYS n 
1 65  GLN n 
1 66  TYR n 
1 67  LYS n 
1 68  ALA n 
1 69  VAL n 
1 70  VAL n 
1 71  TYR n 
1 72  SER n 
1 73  ASN n 
1 74  THR n 
1 75  ILE n 
1 76  GLN n 
1 77  SER n 
1 78  ILE n 
1 79  ILE n 
1 80  ALA n 
1 81  ILE n 
1 82  ILE n 
1 83  ARG n 
1 84  ALA n 
1 85  MET n 
1 86  GLY n 
1 87  ARG n 
1 88  LEU n 
1 89  LYS n 
1 90  ILE n 
1 91  ASP n 
1 92  PHE n 
1 93  GLY n 
1 94  ASP n 
1 95  SER n 
1 96  ALA n 
1 97  ARG n 
1 98  ALA n 
1 99  ASP n 
1 100 ASP n 
1 101 ALA n 
1 102 ARG n 
1 103 GLN n 
1 104 LEU n 
1 105 PHE n 
1 106 VAL n 
1 107 LEU n 
1 108 ALA n 
1 109 GLY n 
1 110 ALA n 
1 111 ALA n 
1 112 GLU n 
1 113 GLU n 
1 114 GLY n 
1 115 PHE n 
1 116 MET n 
1 117 THR n 
1 118 ALA n 
1 119 GLU n 
1 120 LEU n 
1 121 ALA n 
1 122 GLY n 
1 123 VAL n 
1 124 ILE n 
1 125 LYS n 
1 126 ARG n 
1 127 LEU n 
1 128 TRP n 
1 129 LYS n 
1 130 ASP n 
1 131 SER n 
1 132 GLY n 
1 133 VAL n 
1 134 GLN n 
1 135 ALA n 
1 136 CYS n 
1 137 PHE n 
1 138 ASN n 
1 139 ARG n 
1 140 SER n 
1 141 ARG n 
1 142 GLU n 
1 143 TYR n 
1 144 GLN n 
1 145 LEU n 
1 146 ASN n 
1 147 ASP n 
1 148 SER n 
1 149 ALA n 
1 150 ALA n 
1 151 TYR n 
1 152 TYR n 
1 153 LEU n 
1 154 ASN n 
1 155 ASP n 
1 156 LEU n 
1 157 ASP n 
1 158 ARG n 
1 159 ILE n 
1 160 ALA n 
1 161 GLN n 
1 162 PRO n 
1 163 ASN n 
1 164 TYR n 
1 165 ILE n 
1 166 PRO n 
1 167 THR n 
1 168 GLN n 
1 169 GLN n 
1 170 ASP n 
1 171 VAL n 
1 172 LEU n 
1 173 ARG n 
1 174 THR n 
1 175 ARG n 
1 176 VAL n 
1 177 LYS n 
1 178 THR n 
1 179 THR n 
1 180 GLY n 
1 181 ILE n 
1 182 VAL n 
1 183 GLU n 
1 184 THR n 
1 185 HIS n 
1 186 PHE n 
1 187 THR n 
1 188 PHE n 
1 189 LYS n 
1 190 ASP n 
1 191 LEU n 
1 192 HIS n 
1 193 PHE n 
1 194 LYS n 
1 195 MET n 
1 196 PHE n 
1 197 ASP n 
1 198 VAL n 
1 199 GLY n 
1 200 ALA n 
1 201 GLN n 
1 202 ARG n 
1 203 SER n 
1 204 GLU n 
1 205 ARG n 
1 206 LYS n 
1 207 LYS n 
1 208 TRP n 
1 209 ILE n 
1 210 HIS n 
1 211 CYS n 
1 212 PHE n 
1 213 GLU n 
1 214 GLY n 
1 215 VAL n 
1 216 THR n 
1 217 ALA n 
1 218 ILE n 
1 219 ILE n 
1 220 PHE n 
1 221 CYS n 
1 222 VAL n 
1 223 ALA n 
1 224 LEU n 
1 225 SER n 
1 226 ASP n 
1 227 TYR n 
1 228 ASP n 
1 229 LEU n 
1 230 VAL n 
1 231 LEU n 
1 232 ALA n 
1 233 GLU n 
1 234 ASP n 
1 235 GLU n 
1 236 GLU n 
1 237 MET n 
1 238 ASN n 
1 239 ARG n 
1 240 MET n 
1 241 HIS n 
1 242 GLU n 
1 243 SER n 
1 244 MET n 
1 245 LYS n 
1 246 LEU n 
1 247 PHE n 
1 248 ASP n 
1 249 SER n 
1 250 ILE n 
1 251 CYS n 
1 252 ASN n 
1 253 ASN n 
1 254 LYS n 
1 255 TRP n 
1 256 PHE n 
1 257 THR n 
1 258 ASP n 
1 259 THR n 
1 260 SER n 
1 261 ILE n 
1 262 ILE n 
1 263 LEU n 
1 264 PHE n 
1 265 LEU n 
1 266 ASN n 
1 267 LYS n 
1 268 LYS n 
1 269 ASP n 
1 270 LEU n 
1 271 PHE n 
1 272 GLU n 
1 273 GLU n 
1 274 LYS n 
1 275 ILE n 
1 276 LYS n 
1 277 LYS n 
1 278 SER n 
1 279 PRO n 
1 280 LEU n 
1 281 THR n 
1 282 ILE n 
1 283 CYS n 
1 284 TYR n 
1 285 PRO n 
1 286 GLU n 
1 287 TYR n 
1 288 ALA n 
1 289 GLY n 
1 290 SER n 
1 291 ASN n 
1 292 THR n 
1 293 TYR n 
1 294 GLU n 
1 295 GLU n 
1 296 ALA n 
1 297 ALA n 
1 298 ALA n 
1 299 TYR n 
1 300 ILE n 
1 301 GLN n 
1 302 CYS n 
1 303 GLN n 
1 304 PHE n 
1 305 GLU n 
1 306 ASP n 
1 307 LEU n 
1 308 ASN n 
1 309 LYS n 
1 310 ARG n 
1 311 LYS n 
1 312 ASP n 
1 313 THR n 
1 314 LYS n 
1 315 GLU n 
1 316 ILE n 
1 317 TYR n 
1 318 THR n 
1 319 HIS n 
1 320 PHE n 
1 321 THR n 
1 322 CYS n 
1 323 SER n 
1 324 THR n 
1 325 ASP n 
1 326 THR n 
1 327 LYS n 
1 328 ASN n 
1 329 VAL n 
1 330 GLN n 
1 331 PHE n 
1 332 VAL n 
1 333 PHE n 
1 334 ASP n 
1 335 ALA n 
1 336 VAL n 
1 337 THR n 
1 338 ASP n 
1 339 VAL n 
1 340 ILE n 
1 341 ILE n 
1 342 LYS n 
1 343 ASN n 
1 344 ASN n 
1 345 LEU n 
1 346 LYS n 
1 347 ASP n 
1 348 CYS n 
1 349 GLY n 
1 350 LEU n 
1 351 PHE n 
2 1   LEU n 
2 2   ASP n 
2 3   GLN n 
2 4   LEU n 
2 5   ARG n 
2 6   GLN n 
2 7   GLU n 
2 8   ALA n 
2 9   GLU n 
2 10  GLN n 
2 11  LEU n 
2 12  LYS n 
2 13  ASN n 
2 14  GLN n 
2 15  ILE n 
2 16  ARG n 
2 17  ASP n 
2 18  ALA n 
2 19  ARG n 
2 20  LYS n 
2 21  ALA n 
2 22  CYS n 
2 23  ALA n 
2 24  ASP n 
2 25  ALA n 
2 26  THR n 
2 27  LEU n 
2 28  SER n 
2 29  GLN n 
2 30  ILE n 
2 31  THR n 
2 32  ASN n 
2 33  ASN n 
2 34  ILE n 
2 35  ASP n 
2 36  PRO n 
2 37  VAL n 
2 38  GLY n 
2 39  ARG n 
2 40  ILE n 
2 41  GLN n 
2 42  MET n 
2 43  ARG n 
2 44  THR n 
2 45  ARG n 
2 46  ARG n 
2 47  THR n 
2 48  LEU n 
2 49  ARG n 
2 50  GLY n 
2 51  HIS n 
2 52  LEU n 
2 53  ALA n 
2 54  LYS n 
2 55  ILE n 
2 56  TYR n 
2 57  ALA n 
2 58  MET n 
2 59  HIS n 
2 60  TRP n 
2 61  GLY n 
2 62  THR n 
2 63  ASP n 
2 64  SER n 
2 65  ARG n 
2 66  LEU n 
2 67  LEU n 
2 68  VAL n 
2 69  SER n 
2 70  ALA n 
2 71  SER n 
2 72  GLN n 
2 73  ASP n 
2 74  GLY n 
2 75  LYS n 
2 76  LEU n 
2 77  ILE n 
2 78  ILE n 
2 79  TRP n 
2 80  ASP n 
2 81  SER n 
2 82  TYR n 
2 83  THR n 
2 84  THR n 
2 85  ASN n 
2 86  LYS n 
2 87  VAL n 
2 88  HIS n 
2 89  ALA n 
2 90  ILE n 
2 91  PRO n 
2 92  LEU n 
2 93  ARG n 
2 94  SER n 
2 95  SER n 
2 96  TRP n 
2 97  VAL n 
2 98  MET n 
2 99  THR n 
2 100 CYS n 
2 101 ALA n 
2 102 TYR n 
2 103 ALA n 
2 104 PRO n 
2 105 SER n 
2 106 GLY n 
2 107 ASN n 
2 108 TYR n 
2 109 VAL n 
2 110 ALA n 
2 111 CYS n 
2 112 GLY n 
2 113 GLY n 
2 114 LEU n 
2 115 ASP n 
2 116 ASN n 
2 117 ILE n 
2 118 CYS n 
2 119 SER n 
2 120 ILE n 
2 121 TYR n 
2 122 ASN n 
2 123 LEU n 
2 124 LYS n 
2 125 THR n 
2 126 ARG n 
2 127 GLU n 
2 128 GLY n 
2 129 ASN n 
2 130 VAL n 
2 131 ARG n 
2 132 VAL n 
2 133 SER n 
2 134 ARG n 
2 135 GLU n 
2 136 LEU n 
2 137 ALA n 
2 138 GLY n 
2 139 HIS n 
2 140 THR n 
2 141 GLY n 
2 142 TYR n 
2 143 LEU n 
2 144 SER n 
2 145 CYS n 
2 146 CYS n 
2 147 ARG n 
2 148 PHE n 
2 149 LEU n 
2 150 ASP n 
2 151 ASP n 
2 152 ASN n 
2 153 GLN n 
2 154 ILE n 
2 155 VAL n 
2 156 THR n 
2 157 SER n 
2 158 SER n 
2 159 GLY n 
2 160 ASP n 
2 161 THR n 
2 162 THR n 
2 163 CYS n 
2 164 ALA n 
2 165 LEU n 
2 166 TRP n 
2 167 ASP n 
2 168 ILE n 
2 169 GLU n 
2 170 THR n 
2 171 GLY n 
2 172 GLN n 
2 173 GLN n 
2 174 THR n 
2 175 THR n 
2 176 THR n 
2 177 PHE n 
2 178 THR n 
2 179 GLY n 
2 180 HIS n 
2 181 THR n 
2 182 GLY n 
2 183 ASP n 
2 184 VAL n 
2 185 MET n 
2 186 SER n 
2 187 LEU n 
2 188 SER n 
2 189 LEU n 
2 190 ALA n 
2 191 PRO n 
2 192 ASP n 
2 193 THR n 
2 194 ARG n 
2 195 LEU n 
2 196 PHE n 
2 197 VAL n 
2 198 SER n 
2 199 GLY n 
2 200 ALA n 
2 201 CYS n 
2 202 ASP n 
2 203 ALA n 
2 204 SER n 
2 205 ALA n 
2 206 LYS n 
2 207 LEU n 
2 208 TRP n 
2 209 ASP n 
2 210 VAL n 
2 211 ARG n 
2 212 GLU n 
2 213 GLY n 
2 214 MET n 
2 215 CYS n 
2 216 ARG n 
2 217 GLN n 
2 218 THR n 
2 219 PHE n 
2 220 THR n 
2 221 GLY n 
2 222 HIS n 
2 223 GLU n 
2 224 SER n 
2 225 ASP n 
2 226 ILE n 
2 227 ASN n 
2 228 ALA n 
2 229 ILE n 
2 230 CYS n 
2 231 PHE n 
2 232 PHE n 
2 233 PRO n 
2 234 ASN n 
2 235 GLY n 
2 236 ASN n 
2 237 ALA n 
2 238 PHE n 
2 239 ALA n 
2 240 THR n 
2 241 GLY n 
2 242 SER n 
2 243 ASP n 
2 244 ASP n 
2 245 ALA n 
2 246 THR n 
2 247 CYS n 
2 248 ARG n 
2 249 LEU n 
2 250 PHE n 
2 251 ASP n 
2 252 LEU n 
2 253 ARG n 
2 254 ALA n 
2 255 ASP n 
2 256 GLN n 
2 257 GLU n 
2 258 LEU n 
2 259 MET n 
2 260 THR n 
2 261 TYR n 
2 262 SER n 
2 263 HIS n 
2 264 ASP n 
2 265 ASN n 
2 266 ILE n 
2 267 ILE n 
2 268 CYS n 
2 269 GLY n 
2 270 ILE n 
2 271 THR n 
2 272 SER n 
2 273 VAL n 
2 274 SER n 
2 275 PHE n 
2 276 SER n 
2 277 LYS n 
2 278 SER n 
2 279 GLY n 
2 280 ARG n 
2 281 LEU n 
2 282 LEU n 
2 283 LEU n 
2 284 ALA n 
2 285 GLY n 
2 286 TYR n 
2 287 ASP n 
2 288 ASP n 
2 289 PHE n 
2 290 ASN n 
2 291 CYS n 
2 292 ASN n 
2 293 VAL n 
2 294 TRP n 
2 295 ASP n 
2 296 ALA n 
2 297 LEU n 
2 298 LYS n 
2 299 ALA n 
2 300 ASP n 
2 301 ARG n 
2 302 ALA n 
2 303 GLY n 
2 304 VAL n 
2 305 LEU n 
2 306 ALA n 
2 307 GLY n 
2 308 HIS n 
2 309 ASP n 
2 310 ASN n 
2 311 ARG n 
2 312 VAL n 
2 313 SER n 
2 314 CYS n 
2 315 LEU n 
2 316 GLY n 
2 317 VAL n 
2 318 THR n 
2 319 ASP n 
2 320 ASP n 
2 321 GLY n 
2 322 MET n 
2 323 ALA n 
2 324 VAL n 
2 325 ALA n 
2 326 THR n 
2 327 GLY n 
2 328 SER n 
2 329 TRP n 
2 330 ASP n 
2 331 SER n 
2 332 PHE n 
2 333 LEU n 
2 334 LYS n 
2 335 ILE n 
2 336 TRP n 
2 337 ASN n 
3 1   SER n 
3 2   ILE n 
3 3   ALA n 
3 4   GLN n 
3 5   ALA n 
3 6   ARG n 
3 7   LYS n 
3 8   LEU n 
3 9   VAL n 
3 10  GLU n 
3 11  GLN n 
3 12  LEU n 
3 13  LYS n 
3 14  MET n 
3 15  GLU n 
3 16  ALA n 
3 17  ASN n 
3 18  ILE n 
3 19  ASP n 
3 20  ARG n 
3 21  ILE n 
3 22  LYS n 
3 23  VAL n 
3 24  SER n 
3 25  LYS n 
3 26  ALA n 
3 27  ALA n 
3 28  ALA n 
3 29  ASP n 
3 30  LEU n 
3 31  MET n 
3 32  ALA n 
3 33  TYR n 
3 34  CYS n 
3 35  GLU n 
3 36  ALA n 
3 37  HIS n 
3 38  ALA n 
3 39  LYS n 
3 40  GLU n 
3 41  ASP n 
3 42  PRO n 
3 43  LEU n 
3 44  LEU n 
3 45  THR n 
3 46  PRO n 
3 47  VAL n 
3 48  PRO n 
3 49  ALA n 
3 50  SER n 
3 51  GLU n 
3 52  ASN n 
3 53  PRO n 
3 54  PHE n 
3 55  ARG n 
3 56  GLU n 
4 1   ASP n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  ARG n 
4 19  LYS n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  SER n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  ALA n 
4 29  PHE n 
4 30  SER n 
4 31  SER n 
4 32  PHE n 
4 33  GLY n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLU n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  ALA n 
4 50  TYR n 
4 51  ILE n 
4 52  SER n 
4 53  SER n 
4 54  GLY n 
4 55  SER n 
4 56  GLY n 
4 57  THR n 
4 58  ILE n 
4 59  TYR n 
4 60  TYR n 
4 61  ALA n 
4 62  ASP n 
4 63  THR n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASP n 
4 75  PRO n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  PHE n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  ARG n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  MET n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  VAL n 
4 98  ARG n 
4 99  SER n 
4 100 ILE n 
4 101 TYR n 
4 102 TYR n 
4 103 TYR n 
4 104 GLY n 
4 105 SER n 
4 106 SER n 
4 107 PRO n 
4 108 PHE n 
4 109 ASP n 
4 110 PHE n 
4 111 TRP n 
4 112 GLY n 
4 113 GLN n 
4 114 GLY n 
4 115 THR n 
4 116 THR n 
4 117 LEU n 
4 118 THR n 
4 119 VAL n 
4 120 SER n 
4 121 SER n 
4 122 GLY n 
4 123 GLY n 
4 124 GLY n 
4 125 GLY n 
4 126 SER n 
4 127 GLY n 
4 128 GLY n 
4 129 GLY n 
4 130 GLY n 
4 131 SER n 
4 132 GLY n 
4 133 GLY n 
4 134 GLY n 
4 135 GLY n 
4 136 SER n 
4 137 ASP n 
4 138 ILE n 
4 139 VAL n 
4 140 MET n 
4 141 THR n 
4 142 GLN n 
4 143 ALA n 
4 144 THR n 
4 145 SER n 
4 146 SER n 
4 147 VAL n 
4 148 PRO n 
4 149 VAL n 
4 150 THR n 
4 151 PRO n 
4 152 GLY n 
4 153 GLU n 
4 154 SER n 
4 155 VAL n 
4 156 SER n 
4 157 ILE n 
4 158 SER n 
4 159 CYS n 
4 160 ARG n 
4 161 SER n 
4 162 SER n 
4 163 LYS n 
4 164 SER n 
4 165 LEU n 
4 166 LEU n 
4 167 HIS n 
4 168 SER n 
4 169 ASN n 
4 170 GLY n 
4 171 ASN n 
4 172 THR n 
4 173 TYR n 
4 174 LEU n 
4 175 TYR n 
4 176 TRP n 
4 177 PHE n 
4 178 LEU n 
4 179 GLN n 
4 180 ARG n 
4 181 PRO n 
4 182 GLY n 
4 183 GLN n 
4 184 SER n 
4 185 PRO n 
4 186 GLN n 
4 187 LEU n 
4 188 LEU n 
4 189 ILE n 
4 190 TYR n 
4 191 ARG n 
4 192 MET n 
4 193 SER n 
4 194 ASN n 
4 195 LEU n 
4 196 ALA n 
4 197 SER n 
4 198 GLY n 
4 199 VAL n 
4 200 PRO n 
4 201 ASP n 
4 202 ARG n 
4 203 PHE n 
4 204 SER n 
4 205 GLY n 
4 206 SER n 
4 207 GLY n 
4 208 SER n 
4 209 GLY n 
4 210 THR n 
4 211 ALA n 
4 212 PHE n 
4 213 THR n 
4 214 LEU n 
4 215 THR n 
4 216 ILE n 
4 217 SER n 
4 218 ARG n 
4 219 LEU n 
4 220 GLU n 
4 221 ALA n 
4 222 GLU n 
4 223 ASP n 
4 224 VAL n 
4 225 GLY n 
4 226 VAL n 
4 227 TYR n 
4 228 TYR n 
4 229 CYS n 
4 230 MET n 
4 231 GLN n 
4 232 HIS n 
4 233 LEU n 
4 234 GLU n 
4 235 TYR n 
4 236 PRO n 
4 237 LEU n 
4 238 THR n 
4 239 PHE n 
4 240 GLY n 
4 241 ALA n 
4 242 GLY n 
4 243 THR n 
4 244 LYS n 
4 245 LEU n 
4 246 GLU n 
4 247 LEU n 
5 1   MET n 
5 2   ASN n 
5 3   ARG n 
5 4   HIS n 
5 5   HIS n 
5 6   LEU n 
5 7   GLN n 
5 8   ASP n 
5 9   HIS n 
5 10  PHE n 
5 11  LEU n 
5 12  GLU n 
5 13  ILE n 
5 14  ASP n 
5 15  LYS n 
5 16  LYS n 
5 17  ASN n 
5 18  CYS n 
5 19  CYS n 
5 20  VAL n 
5 21  PHE n 
5 22  ARG n 
5 23  ASP n 
5 24  ASP n 
5 25  PHE n 
5 26  ILE n 
5 27  ALA n 
5 28  LYS n 
5 29  VAL n 
5 30  LEU n 
5 31  PRO n 
5 32  PRO n 
5 33  VAL n 
5 34  LEU n 
5 35  GLY n 
5 36  LEU n 
5 37  GLU n 
5 38  PHE n 
5 39  ILE n 
5 40  PHE n 
5 41  GLY n 
5 42  LEU n 
5 43  LEU n 
5 44  GLY n 
5 45  ASN n 
5 46  GLY n 
5 47  LEU n 
5 48  ALA n 
5 49  LEU n 
5 50  TRP n 
5 51  ILE n 
5 52  PHE n 
5 53  CYS n 
5 54  PHE n 
5 55  HIS n 
5 56  LEU n 
5 57  LYS n 
5 58  SER n 
5 59  TRP n 
5 60  LYS n 
5 61  SER n 
5 62  SER n 
5 63  ARG n 
5 64  ILE n 
5 65  PHE n 
5 66  LEU n 
5 67  PHE n 
5 68  ASN n 
5 69  LEU n 
5 70  ALA n 
5 71  VAL n 
5 72  ALA n 
5 73  ASP n 
5 74  PHE n 
5 75  LEU n 
5 76  LEU n 
5 77  ILE n 
5 78  ILE n 
5 79  CYS n 
5 80  LEU n 
5 81  PRO n 
5 82  PHE n 
5 83  VAL n 
5 84  MET n 
5 85  ASP n 
5 86  TYR n 
5 87  TYR n 
5 88  VAL n 
5 89  ARG n 
5 90  ARG n 
5 91  SER n 
5 92  ASP n 
5 93  TRP n 
5 94  LYS n 
5 95  PHE n 
5 96  GLY n 
5 97  ASP n 
5 98  ILE n 
5 99  PRO n 
5 100 CYS n 
5 101 ARG n 
5 102 LEU n 
5 103 VAL n 
5 104 LEU n 
5 105 PHE n 
5 106 MET n 
5 107 PHE n 
5 108 ALA n 
5 109 MET n 
5 110 ASN n 
5 111 ARG n 
5 112 GLN n 
5 113 GLY n 
5 114 SER n 
5 115 ILE n 
5 116 ILE n 
5 117 PHE n 
5 118 LEU n 
5 119 THR n 
5 120 VAL n 
5 121 VAL n 
5 122 ALA n 
5 123 VAL n 
5 124 ASP n 
5 125 ARG n 
5 126 TYR n 
5 127 PHE n 
5 128 ARG n 
5 129 VAL n 
5 130 VAL n 
5 131 HIS n 
5 132 PRO n 
5 133 HIS n 
5 134 HIS n 
5 135 ALA n 
5 136 LEU n 
5 137 ASN n 
5 138 LYS n 
5 139 ILE n 
5 140 SER n 
5 141 ASN n 
5 142 TRP n 
5 143 THR n 
5 144 ALA n 
5 145 ALA n 
5 146 ILE n 
5 147 ILE n 
5 148 SER n 
5 149 CYS n 
5 150 LEU n 
5 151 LEU n 
5 152 TRP n 
5 153 GLY n 
5 154 ILE n 
5 155 THR n 
5 156 VAL n 
5 157 GLY n 
5 158 LEU n 
5 159 THR n 
5 160 VAL n 
5 161 HIS n 
5 162 LEU n 
5 163 LEU n 
5 164 LYS n 
5 165 LYS n 
5 166 LYS n 
5 167 LEU n 
5 168 LEU n 
5 169 ILE n 
5 170 GLN n 
5 171 ASN n 
5 172 GLY n 
5 173 THR n 
5 174 ALA n 
5 175 ASN n 
5 176 VAL n 
5 177 CYS n 
5 178 ILE n 
5 179 SER n 
5 180 PHE n 
5 181 SER n 
5 182 ILE n 
5 183 CYS n 
5 184 HIS n 
5 185 THR n 
5 186 PHE n 
5 187 ARG n 
5 188 TRP n 
5 189 HIS n 
5 190 GLU n 
5 191 ALA n 
5 192 MET n 
5 193 PHE n 
5 194 LEU n 
5 195 LEU n 
5 196 GLU n 
5 197 PHE n 
5 198 PHE n 
5 199 LEU n 
5 200 PRO n 
5 201 LEU n 
5 202 GLY n 
5 203 ILE n 
5 204 ILE n 
5 205 LEU n 
5 206 PHE n 
5 207 CYS n 
5 208 SER n 
5 209 ALA n 
5 210 ARG n 
5 211 ILE n 
5 212 ILE n 
5 213 TRP n 
5 214 SER n 
5 215 LEU n 
5 216 ARG n 
5 217 GLN n 
5 218 ARG n 
5 219 GLN n 
5 220 MET n 
5 221 ASP n 
5 222 ARG n 
5 223 HIS n 
5 224 ALA n 
5 225 LYS n 
5 226 ILE n 
5 227 LYS n 
5 228 ARG n 
5 229 ALA n 
5 230 ILE n 
5 231 THR n 
5 232 PHE n 
5 233 ILE n 
5 234 MET n 
5 235 VAL n 
5 236 VAL n 
5 237 ALA n 
5 238 ILE n 
5 239 VAL n 
5 240 PHE n 
5 241 VAL n 
5 242 ILE n 
5 243 CYS n 
5 244 PHE n 
5 245 LEU n 
5 246 PRO n 
5 247 SER n 
5 248 VAL n 
5 249 VAL n 
5 250 VAL n 
5 251 ARG n 
5 252 ILE n 
5 253 HIS n 
5 254 ILE n 
5 255 PHE n 
5 256 TRP n 
5 257 LEU n 
5 258 LEU n 
5 259 HIS n 
5 260 THR n 
5 261 SER n 
5 262 GLY n 
5 263 THR n 
5 264 GLN n 
5 265 ASN n 
5 266 CYS n 
5 267 GLU n 
5 268 VAL n 
5 269 TYR n 
5 270 ARG n 
5 271 SER n 
5 272 VAL n 
5 273 ASP n 
5 274 LEU n 
5 275 ALA n 
5 276 PHE n 
5 277 PHE n 
5 278 ILE n 
5 279 THR n 
5 280 LEU n 
5 281 SER n 
5 282 PHE n 
5 283 THR n 
5 284 TYR n 
5 285 MET n 
5 286 ASN n 
5 287 SER n 
5 288 MET n 
5 289 LEU n 
5 290 ASP n 
5 291 PRO n 
5 292 VAL n 
5 293 VAL n 
5 294 TYR n 
5 295 TYR n 
5 296 PHE n 
5 297 SER n 
5 298 SER n 
5 299 PRO n 
5 300 SER n 
5 301 PHE n 
5 302 PRO n 
5 303 ASN n 
5 304 PHE n 
5 305 PHE n 
5 306 SER n 
5 307 THR n 
5 308 LEU n 
5 309 ILE n 
5 310 ASN n 
5 311 ARG n 
5 312 CYS n 
5 313 LEU n 
5 314 GLN n 
5 315 ARG n 
5 316 LYS n 
5 317 ILE n 
5 318 THR n 
5 319 GLY n 
5 320 GLU n 
5 321 PRO n 
5 322 ASP n 
5 323 ASN n 
5 324 ASN n 
5 325 ARG n 
5 326 SER n 
5 327 THR n 
5 328 SER n 
5 329 VAL n 
5 330 GLU n 
5 331 LEU n 
5 332 THR n 
5 333 GLY n 
5 334 ASP n 
5 335 PRO n 
5 336 ASN n 
5 337 LYS n 
5 338 THR n 
5 339 ARG n 
5 340 GLY n 
5 341 ALA n 
5 342 PRO n 
5 343 GLU n 
5 344 ALA n 
5 345 LEU n 
5 346 ILE n 
5 347 ALA n 
5 348 ASN n 
5 349 SER n 
5 350 GLY n 
5 351 GLU n 
5 352 PRO n 
5 353 TRP n 
5 354 SER n 
5 355 PRO n 
5 356 SER n 
5 357 TYR n 
5 358 LEU n 
5 359 GLY n 
5 360 PRO n 
5 361 THR n 
5 362 SER n 
5 363 ASN n 
5 364 ASN n 
5 365 HIS n 
5 366 SER n 
5 367 LYS n 
5 368 LYS n 
5 369 GLY n 
5 370 HIS n 
5 371 CYS n 
5 372 HIS n 
5 373 GLN n 
5 374 GLU n 
5 375 PRO n 
5 376 ALA n 
5 377 SER n 
5 378 LEU n 
5 379 GLU n 
5 380 LYS n 
5 381 GLN n 
5 382 LEU n 
5 383 GLY n 
5 384 CYS n 
5 385 CYS n 
5 386 ILE n 
5 387 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 351 human ? GNAI1                                 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 337 human ? GNB1                                  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 56  human ? GNG2                                  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 247 human ? ?                                     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 387 human ? 'HCAR3, GPR109B, HCA3, HM74B, NIACR2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                               ?          'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                              ?          'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                            ?          'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                       ?          'C4 H7 N O4'     133.103 
CW3 non-polymer         . '3-nitro-4-(propylamino)benzoic acid' 68740-31-8 'C10 H12 N2 O4'  224.213 
CYS 'L-peptide linking' y CYSTEINE                              ?          'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                             ?          'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                       ?          'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                               ?          'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                             ?          'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                            ?          'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                               ?          'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                ?          'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                            ?          'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                         ?          'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                               ?          'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                ?          'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                             ?          'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                            ?          'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                              ?          'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                ?          'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   THR 1   4   4   THR THR C . n 
A 1 2   LEU 2   5   5   LEU LEU C . n 
A 1 3   SER 3   6   6   SER SER C . n 
A 1 4   ALA 4   7   7   ALA ALA C . n 
A 1 5   GLU 5   8   8   GLU GLU C . n 
A 1 6   ASP 6   9   9   ASP ASP C . n 
A 1 7   LYS 7   10  10  LYS LYS C . n 
A 1 8   ALA 8   11  11  ALA ALA C . n 
A 1 9   ALA 9   12  12  ALA ALA C . n 
A 1 10  VAL 10  13  13  VAL VAL C . n 
A 1 11  GLU 11  14  14  GLU GLU C . n 
A 1 12  ARG 12  15  15  ARG ARG C . n 
A 1 13  SER 13  16  16  SER SER C . n 
A 1 14  LYS 14  17  17  LYS LYS C . n 
A 1 15  MET 15  18  18  MET MET C . n 
A 1 16  ILE 16  19  19  ILE ILE C . n 
A 1 17  ASP 17  20  20  ASP ASP C . n 
A 1 18  ARG 18  21  21  ARG ARG C . n 
A 1 19  ASN 19  22  22  ASN ASN C . n 
A 1 20  LEU 20  23  23  LEU LEU C . n 
A 1 21  ARG 21  24  24  ARG ARG C . n 
A 1 22  GLU 22  25  25  GLU GLU C . n 
A 1 23  ASP 23  26  26  ASP ASP C . n 
A 1 24  GLY 24  27  27  GLY GLY C . n 
A 1 25  GLU 25  28  28  GLU GLU C . n 
A 1 26  LYS 26  29  29  LYS LYS C . n 
A 1 27  ALA 27  30  30  ALA ALA C . n 
A 1 28  ALA 28  31  31  ALA ALA C . n 
A 1 29  ARG 29  32  32  ARG ARG C . n 
A 1 30  GLU 30  33  33  GLU GLU C . n 
A 1 31  VAL 31  34  34  VAL VAL C . n 
A 1 32  LYS 32  35  35  LYS LYS C . n 
A 1 33  LEU 33  36  36  LEU LEU C . n 
A 1 34  LEU 34  37  37  LEU LEU C . n 
A 1 35  LEU 35  38  38  LEU LEU C . n 
A 1 36  LEU 36  39  39  LEU LEU C . n 
A 1 37  GLY 37  40  40  GLY GLY C . n 
A 1 38  ALA 38  41  41  ALA ALA C . n 
A 1 39  GLY 39  42  42  GLY GLY C . n 
A 1 40  GLU 40  43  43  GLU GLU C . n 
A 1 41  SER 41  44  44  SER SER C . n 
A 1 42  GLY 42  45  45  GLY GLY C . n 
A 1 43  LYS 43  46  46  LYS LYS C . n 
A 1 44  SER 44  47  47  SER SER C . n 
A 1 45  THR 45  48  48  THR THR C . n 
A 1 46  ILE 46  49  49  ILE ILE C . n 
A 1 47  VAL 47  50  50  VAL VAL C . n 
A 1 48  LYS 48  51  51  LYS LYS C . n 
A 1 49  GLN 49  52  52  GLN GLN C . n 
A 1 50  MET 50  53  53  MET MET C . n 
A 1 51  LYS 51  54  ?   ?   ?   C . n 
A 1 52  ILE 52  55  ?   ?   ?   C . n 
A 1 53  ILE 53  56  ?   ?   ?   C . n 
A 1 54  HIS 54  57  ?   ?   ?   C . n 
A 1 55  GLU 55  58  ?   ?   ?   C . n 
A 1 56  ALA 56  59  ?   ?   ?   C . n 
A 1 57  GLY 57  60  ?   ?   ?   C . n 
A 1 58  TYR 58  61  ?   ?   ?   C . n 
A 1 59  SER 59  62  ?   ?   ?   C . n 
A 1 60  GLU 60  63  ?   ?   ?   C . n 
A 1 61  GLU 61  64  ?   ?   ?   C . n 
A 1 62  GLU 62  65  ?   ?   ?   C . n 
A 1 63  CYS 63  66  ?   ?   ?   C . n 
A 1 64  LYS 64  67  ?   ?   ?   C . n 
A 1 65  GLN 65  68  ?   ?   ?   C . n 
A 1 66  TYR 66  69  ?   ?   ?   C . n 
A 1 67  LYS 67  70  ?   ?   ?   C . n 
A 1 68  ALA 68  71  ?   ?   ?   C . n 
A 1 69  VAL 69  72  ?   ?   ?   C . n 
A 1 70  VAL 70  73  ?   ?   ?   C . n 
A 1 71  TYR 71  74  ?   ?   ?   C . n 
A 1 72  SER 72  75  ?   ?   ?   C . n 
A 1 73  ASN 73  76  ?   ?   ?   C . n 
A 1 74  THR 74  77  ?   ?   ?   C . n 
A 1 75  ILE 75  78  ?   ?   ?   C . n 
A 1 76  GLN 76  79  ?   ?   ?   C . n 
A 1 77  SER 77  80  ?   ?   ?   C . n 
A 1 78  ILE 78  81  ?   ?   ?   C . n 
A 1 79  ILE 79  82  ?   ?   ?   C . n 
A 1 80  ALA 80  83  ?   ?   ?   C . n 
A 1 81  ILE 81  84  ?   ?   ?   C . n 
A 1 82  ILE 82  85  ?   ?   ?   C . n 
A 1 83  ARG 83  86  ?   ?   ?   C . n 
A 1 84  ALA 84  87  ?   ?   ?   C . n 
A 1 85  MET 85  88  ?   ?   ?   C . n 
A 1 86  GLY 86  89  ?   ?   ?   C . n 
A 1 87  ARG 87  90  ?   ?   ?   C . n 
A 1 88  LEU 88  91  ?   ?   ?   C . n 
A 1 89  LYS 89  92  ?   ?   ?   C . n 
A 1 90  ILE 90  93  ?   ?   ?   C . n 
A 1 91  ASP 91  94  ?   ?   ?   C . n 
A 1 92  PHE 92  95  ?   ?   ?   C . n 
A 1 93  GLY 93  96  ?   ?   ?   C . n 
A 1 94  ASP 94  97  ?   ?   ?   C . n 
A 1 95  SER 95  98  ?   ?   ?   C . n 
A 1 96  ALA 96  99  ?   ?   ?   C . n 
A 1 97  ARG 97  100 ?   ?   ?   C . n 
A 1 98  ALA 98  101 ?   ?   ?   C . n 
A 1 99  ASP 99  102 ?   ?   ?   C . n 
A 1 100 ASP 100 103 ?   ?   ?   C . n 
A 1 101 ALA 101 104 ?   ?   ?   C . n 
A 1 102 ARG 102 105 ?   ?   ?   C . n 
A 1 103 GLN 103 106 ?   ?   ?   C . n 
A 1 104 LEU 104 107 ?   ?   ?   C . n 
A 1 105 PHE 105 108 ?   ?   ?   C . n 
A 1 106 VAL 106 109 ?   ?   ?   C . n 
A 1 107 LEU 107 110 ?   ?   ?   C . n 
A 1 108 ALA 108 111 ?   ?   ?   C . n 
A 1 109 GLY 109 112 ?   ?   ?   C . n 
A 1 110 ALA 110 113 ?   ?   ?   C . n 
A 1 111 ALA 111 114 ?   ?   ?   C . n 
A 1 112 GLU 112 115 ?   ?   ?   C . n 
A 1 113 GLU 113 116 ?   ?   ?   C . n 
A 1 114 GLY 114 117 ?   ?   ?   C . n 
A 1 115 PHE 115 118 ?   ?   ?   C . n 
A 1 116 MET 116 119 ?   ?   ?   C . n 
A 1 117 THR 117 120 ?   ?   ?   C . n 
A 1 118 ALA 118 121 ?   ?   ?   C . n 
A 1 119 GLU 119 122 ?   ?   ?   C . n 
A 1 120 LEU 120 123 ?   ?   ?   C . n 
A 1 121 ALA 121 124 ?   ?   ?   C . n 
A 1 122 GLY 122 125 ?   ?   ?   C . n 
A 1 123 VAL 123 126 ?   ?   ?   C . n 
A 1 124 ILE 124 127 ?   ?   ?   C . n 
A 1 125 LYS 125 128 ?   ?   ?   C . n 
A 1 126 ARG 126 129 ?   ?   ?   C . n 
A 1 127 LEU 127 130 ?   ?   ?   C . n 
A 1 128 TRP 128 131 ?   ?   ?   C . n 
A 1 129 LYS 129 132 ?   ?   ?   C . n 
A 1 130 ASP 130 133 ?   ?   ?   C . n 
A 1 131 SER 131 134 ?   ?   ?   C . n 
A 1 132 GLY 132 135 ?   ?   ?   C . n 
A 1 133 VAL 133 136 ?   ?   ?   C . n 
A 1 134 GLN 134 137 ?   ?   ?   C . n 
A 1 135 ALA 135 138 ?   ?   ?   C . n 
A 1 136 CYS 136 139 ?   ?   ?   C . n 
A 1 137 PHE 137 140 ?   ?   ?   C . n 
A 1 138 ASN 138 141 ?   ?   ?   C . n 
A 1 139 ARG 139 142 ?   ?   ?   C . n 
A 1 140 SER 140 143 ?   ?   ?   C . n 
A 1 141 ARG 141 144 ?   ?   ?   C . n 
A 1 142 GLU 142 145 ?   ?   ?   C . n 
A 1 143 TYR 143 146 ?   ?   ?   C . n 
A 1 144 GLN 144 147 ?   ?   ?   C . n 
A 1 145 LEU 145 148 ?   ?   ?   C . n 
A 1 146 ASN 146 149 ?   ?   ?   C . n 
A 1 147 ASP 147 150 ?   ?   ?   C . n 
A 1 148 SER 148 151 ?   ?   ?   C . n 
A 1 149 ALA 149 152 ?   ?   ?   C . n 
A 1 150 ALA 150 153 ?   ?   ?   C . n 
A 1 151 TYR 151 154 ?   ?   ?   C . n 
A 1 152 TYR 152 155 ?   ?   ?   C . n 
A 1 153 LEU 153 156 ?   ?   ?   C . n 
A 1 154 ASN 154 157 ?   ?   ?   C . n 
A 1 155 ASP 155 158 ?   ?   ?   C . n 
A 1 156 LEU 156 159 ?   ?   ?   C . n 
A 1 157 ASP 157 160 ?   ?   ?   C . n 
A 1 158 ARG 158 161 ?   ?   ?   C . n 
A 1 159 ILE 159 162 ?   ?   ?   C . n 
A 1 160 ALA 160 163 ?   ?   ?   C . n 
A 1 161 GLN 161 164 ?   ?   ?   C . n 
A 1 162 PRO 162 165 ?   ?   ?   C . n 
A 1 163 ASN 163 166 ?   ?   ?   C . n 
A 1 164 TYR 164 167 ?   ?   ?   C . n 
A 1 165 ILE 165 168 ?   ?   ?   C . n 
A 1 166 PRO 166 169 ?   ?   ?   C . n 
A 1 167 THR 167 170 ?   ?   ?   C . n 
A 1 168 GLN 168 171 ?   ?   ?   C . n 
A 1 169 GLN 169 172 ?   ?   ?   C . n 
A 1 170 ASP 170 173 ?   ?   ?   C . n 
A 1 171 VAL 171 174 ?   ?   ?   C . n 
A 1 172 LEU 172 175 ?   ?   ?   C . n 
A 1 173 ARG 173 176 ?   ?   ?   C . n 
A 1 174 THR 174 177 ?   ?   ?   C . n 
A 1 175 ARG 175 178 ?   ?   ?   C . n 
A 1 176 VAL 176 179 ?   ?   ?   C . n 
A 1 177 LYS 177 180 ?   ?   ?   C . n 
A 1 178 THR 178 181 ?   ?   ?   C . n 
A 1 179 THR 179 182 182 THR THR C . n 
A 1 180 GLY 180 183 183 GLY GLY C . n 
A 1 181 ILE 181 184 184 ILE ILE C . n 
A 1 182 VAL 182 185 185 VAL VAL C . n 
A 1 183 GLU 183 186 186 GLU GLU C . n 
A 1 184 THR 184 187 187 THR THR C . n 
A 1 185 HIS 185 188 188 HIS HIS C . n 
A 1 186 PHE 186 189 189 PHE PHE C . n 
A 1 187 THR 187 190 190 THR THR C . n 
A 1 188 PHE 188 191 191 PHE PHE C . n 
A 1 189 LYS 189 192 192 LYS LYS C . n 
A 1 190 ASP 190 193 193 ASP ASP C . n 
A 1 191 LEU 191 194 194 LEU LEU C . n 
A 1 192 HIS 192 195 195 HIS HIS C . n 
A 1 193 PHE 193 196 196 PHE PHE C . n 
A 1 194 LYS 194 197 197 LYS LYS C . n 
A 1 195 MET 195 198 198 MET MET C . n 
A 1 196 PHE 196 199 199 PHE PHE C . n 
A 1 197 ASP 197 200 200 ASP ASP C . n 
A 1 198 VAL 198 201 201 VAL VAL C . n 
A 1 199 GLY 199 202 202 GLY GLY C . n 
A 1 200 ALA 200 203 203 ALA GLY C . n 
A 1 201 GLN 201 204 204 GLN GLN C . n 
A 1 202 ARG 202 205 205 ARG ARG C . n 
A 1 203 SER 203 206 206 SER SER C . n 
A 1 204 GLU 204 207 207 GLU GLU C . n 
A 1 205 ARG 205 208 208 ARG ARG C . n 
A 1 206 LYS 206 209 209 LYS LYS C . n 
A 1 207 LYS 207 210 210 LYS LYS C . n 
A 1 208 TRP 208 211 211 TRP TRP C . n 
A 1 209 ILE 209 212 212 ILE ILE C . n 
A 1 210 HIS 210 213 213 HIS HIS C . n 
A 1 211 CYS 211 214 214 CYS CYS C . n 
A 1 212 PHE 212 215 215 PHE PHE C . n 
A 1 213 GLU 213 216 216 GLU GLU C . n 
A 1 214 GLY 214 217 217 GLY GLY C . n 
A 1 215 VAL 215 218 218 VAL VAL C . n 
A 1 216 THR 216 219 219 THR THR C . n 
A 1 217 ALA 217 220 220 ALA ALA C . n 
A 1 218 ILE 218 221 221 ILE ILE C . n 
A 1 219 ILE 219 222 222 ILE ILE C . n 
A 1 220 PHE 220 223 223 PHE PHE C . n 
A 1 221 CYS 221 224 224 CYS CYS C . n 
A 1 222 VAL 222 225 225 VAL VAL C . n 
A 1 223 ALA 223 226 226 ALA ALA C . n 
A 1 224 LEU 224 227 227 LEU LEU C . n 
A 1 225 SER 225 228 228 SER SER C . n 
A 1 226 ASP 226 229 229 ASP ASP C . n 
A 1 227 TYR 227 230 230 TYR TYR C . n 
A 1 228 ASP 228 231 231 ASP ASP C . n 
A 1 229 LEU 229 232 232 LEU LEU C . n 
A 1 230 VAL 230 233 233 VAL VAL C . n 
A 1 231 LEU 231 234 ?   ?   ?   C . n 
A 1 232 ALA 232 235 ?   ?   ?   C . n 
A 1 233 GLU 233 236 ?   ?   ?   C . n 
A 1 234 ASP 234 237 ?   ?   ?   C . n 
A 1 235 GLU 235 238 ?   ?   ?   C . n 
A 1 236 GLU 236 239 ?   ?   ?   C . n 
A 1 237 MET 237 240 ?   ?   ?   C . n 
A 1 238 ASN 238 241 241 ASN ASN C . n 
A 1 239 ARG 239 242 242 ARG ARG C . n 
A 1 240 MET 240 243 243 MET MET C . n 
A 1 241 HIS 241 244 244 HIS HIS C . n 
A 1 242 GLU 242 245 245 GLU GLU C . n 
A 1 243 SER 243 246 246 SER SER C . n 
A 1 244 MET 244 247 247 MET MET C . n 
A 1 245 LYS 245 248 248 LYS LYS C . n 
A 1 246 LEU 246 249 249 LEU LEU C . n 
A 1 247 PHE 247 250 250 PHE PHE C . n 
A 1 248 ASP 248 251 251 ASP ASP C . n 
A 1 249 SER 249 252 252 SER SER C . n 
A 1 250 ILE 250 253 253 ILE ILE C . n 
A 1 251 CYS 251 254 254 CYS CYS C . n 
A 1 252 ASN 252 255 255 ASN ASN C . n 
A 1 253 ASN 253 256 256 ASN ASN C . n 
A 1 254 LYS 254 257 257 LYS LYS C . n 
A 1 255 TRP 255 258 258 TRP TRP C . n 
A 1 256 PHE 256 259 259 PHE PHE C . n 
A 1 257 THR 257 260 260 THR THR C . n 
A 1 258 ASP 258 261 261 ASP ASP C . n 
A 1 259 THR 259 262 262 THR THR C . n 
A 1 260 SER 260 263 263 SER SER C . n 
A 1 261 ILE 261 264 264 ILE ILE C . n 
A 1 262 ILE 262 265 265 ILE ILE C . n 
A 1 263 LEU 263 266 266 LEU LEU C . n 
A 1 264 PHE 264 267 267 PHE PHE C . n 
A 1 265 LEU 265 268 268 LEU LEU C . n 
A 1 266 ASN 266 269 269 ASN ASN C . n 
A 1 267 LYS 267 270 270 LYS LYS C . n 
A 1 268 LYS 268 271 271 LYS LYS C . n 
A 1 269 ASP 269 272 272 ASP ASP C . n 
A 1 270 LEU 270 273 273 LEU LEU C . n 
A 1 271 PHE 271 274 274 PHE PHE C . n 
A 1 272 GLU 272 275 275 GLU GLU C . n 
A 1 273 GLU 273 276 276 GLU GLU C . n 
A 1 274 LYS 274 277 277 LYS LYS C . n 
A 1 275 ILE 275 278 278 ILE ILE C . n 
A 1 276 LYS 276 279 279 LYS LYS C . n 
A 1 277 LYS 277 280 280 LYS LYS C . n 
A 1 278 SER 278 281 281 SER SER C . n 
A 1 279 PRO 279 282 282 PRO PRO C . n 
A 1 280 LEU 280 283 283 LEU LEU C . n 
A 1 281 THR 281 284 284 THR THR C . n 
A 1 282 ILE 282 285 285 ILE ILE C . n 
A 1 283 CYS 283 286 286 CYS CYS C . n 
A 1 284 TYR 284 287 287 TYR TYR C . n 
A 1 285 PRO 285 288 288 PRO PRO C . n 
A 1 286 GLU 286 289 289 GLU GLU C . n 
A 1 287 TYR 287 290 290 TYR TYR C . n 
A 1 288 ALA 288 291 291 ALA ALA C . n 
A 1 289 GLY 289 292 292 GLY GLY C . n 
A 1 290 SER 290 293 293 SER SER C . n 
A 1 291 ASN 291 294 294 ASN ASN C . n 
A 1 292 THR 292 295 295 THR THR C . n 
A 1 293 TYR 293 296 296 TYR TYR C . n 
A 1 294 GLU 294 297 297 GLU GLU C . n 
A 1 295 GLU 295 298 298 GLU GLU C . n 
A 1 296 ALA 296 299 299 ALA ALA C . n 
A 1 297 ALA 297 300 300 ALA ALA C . n 
A 1 298 ALA 298 301 301 ALA ALA C . n 
A 1 299 TYR 299 302 302 TYR TYR C . n 
A 1 300 ILE 300 303 303 ILE ILE C . n 
A 1 301 GLN 301 304 304 GLN GLN C . n 
A 1 302 CYS 302 305 305 CYS CYS C . n 
A 1 303 GLN 303 306 306 GLN GLN C . n 
A 1 304 PHE 304 307 307 PHE PHE C . n 
A 1 305 GLU 305 308 308 GLU GLU C . n 
A 1 306 ASP 306 309 309 ASP ASP C . n 
A 1 307 LEU 307 310 310 LEU LEU C . n 
A 1 308 ASN 308 311 311 ASN ASN C . n 
A 1 309 LYS 309 312 312 LYS LYS C . n 
A 1 310 ARG 310 313 313 ARG ARG C . n 
A 1 311 LYS 311 314 314 LYS LYS C . n 
A 1 312 ASP 312 315 315 ASP ASP C . n 
A 1 313 THR 313 316 316 THR THR C . n 
A 1 314 LYS 314 317 317 LYS LYS C . n 
A 1 315 GLU 315 318 318 GLU GLU C . n 
A 1 316 ILE 316 319 319 ILE ILE C . n 
A 1 317 TYR 317 320 320 TYR TYR C . n 
A 1 318 THR 318 321 321 THR THR C . n 
A 1 319 HIS 319 322 322 HIS HIS C . n 
A 1 320 PHE 320 323 323 PHE PHE C . n 
A 1 321 THR 321 324 324 THR THR C . n 
A 1 322 CYS 322 325 325 CYS CYS C . n 
A 1 323 SER 323 326 326 SER ALA C . n 
A 1 324 THR 324 327 327 THR THR C . n 
A 1 325 ASP 325 328 328 ASP ASP C . n 
A 1 326 THR 326 329 329 THR THR C . n 
A 1 327 LYS 327 330 330 LYS LYS C . n 
A 1 328 ASN 328 331 331 ASN ASN C . n 
A 1 329 VAL 329 332 332 VAL VAL C . n 
A 1 330 GLN 330 333 333 GLN GLN C . n 
A 1 331 PHE 331 334 334 PHE PHE C . n 
A 1 332 VAL 332 335 335 VAL VAL C . n 
A 1 333 PHE 333 336 336 PHE PHE C . n 
A 1 334 ASP 334 337 337 ASP ASP C . n 
A 1 335 ALA 335 338 338 ALA ALA C . n 
A 1 336 VAL 336 339 339 VAL VAL C . n 
A 1 337 THR 337 340 340 THR THR C . n 
A 1 338 ASP 338 341 341 ASP ASP C . n 
A 1 339 VAL 339 342 342 VAL VAL C . n 
A 1 340 ILE 340 343 343 ILE ILE C . n 
A 1 341 ILE 341 344 344 ILE ILE C . n 
A 1 342 LYS 342 345 345 LYS LYS C . n 
A 1 343 ASN 343 346 346 ASN ASN C . n 
A 1 344 ASN 344 347 347 ASN ASN C . n 
A 1 345 LEU 345 348 348 LEU LEU C . n 
A 1 346 LYS 346 349 349 LYS LYS C . n 
A 1 347 ASP 347 350 350 ASP ASP C . n 
A 1 348 CYS 348 351 351 CYS CYS C . n 
A 1 349 GLY 349 352 352 GLY GLY C . n 
A 1 350 LEU 350 353 353 LEU LEU C . n 
A 1 351 PHE 351 354 354 PHE PHE C . n 
B 2 1   LEU 1   4   4   LEU LEU B . n 
B 2 2   ASP 2   5   5   ASP ASP B . n 
B 2 3   GLN 3   6   6   GLN GLN B . n 
B 2 4   LEU 4   7   7   LEU LEU B . n 
B 2 5   ARG 5   8   8   ARG ARG B . n 
B 2 6   GLN 6   9   9   GLN GLN B . n 
B 2 7   GLU 7   10  10  GLU GLU B . n 
B 2 8   ALA 8   11  11  ALA ALA B . n 
B 2 9   GLU 9   12  12  GLU GLU B . n 
B 2 10  GLN 10  13  13  GLN GLN B . n 
B 2 11  LEU 11  14  14  LEU LEU B . n 
B 2 12  LYS 12  15  15  LYS LYS B . n 
B 2 13  ASN 13  16  16  ASN ASN B . n 
B 2 14  GLN 14  17  17  GLN GLN B . n 
B 2 15  ILE 15  18  18  ILE ILE B . n 
B 2 16  ARG 16  19  19  ARG ARG B . n 
B 2 17  ASP 17  20  20  ASP ASP B . n 
B 2 18  ALA 18  21  21  ALA ALA B . n 
B 2 19  ARG 19  22  22  ARG ARG B . n 
B 2 20  LYS 20  23  23  LYS LYS B . n 
B 2 21  ALA 21  24  24  ALA ALA B . n 
B 2 22  CYS 22  25  25  CYS CYS B . n 
B 2 23  ALA 23  26  26  ALA ALA B . n 
B 2 24  ASP 24  27  27  ASP ASP B . n 
B 2 25  ALA 25  28  28  ALA ALA B . n 
B 2 26  THR 26  29  29  THR THR B . n 
B 2 27  LEU 27  30  30  LEU LEU B . n 
B 2 28  SER 28  31  31  SER SER B . n 
B 2 29  GLN 29  32  32  GLN GLN B . n 
B 2 30  ILE 30  33  33  ILE ILE B . n 
B 2 31  THR 31  34  34  THR THR B . n 
B 2 32  ASN 32  35  35  ASN ASN B . n 
B 2 33  ASN 33  36  36  ASN ASN B . n 
B 2 34  ILE 34  37  37  ILE ILE B . n 
B 2 35  ASP 35  38  38  ASP ASP B . n 
B 2 36  PRO 36  39  39  PRO PRO B . n 
B 2 37  VAL 37  40  40  VAL VAL B . n 
B 2 38  GLY 38  41  41  GLY GLY B . n 
B 2 39  ARG 39  42  42  ARG ARG B . n 
B 2 40  ILE 40  43  43  ILE ILE B . n 
B 2 41  GLN 41  44  44  GLN GLN B . n 
B 2 42  MET 42  45  45  MET MET B . n 
B 2 43  ARG 43  46  46  ARG ARG B . n 
B 2 44  THR 44  47  47  THR THR B . n 
B 2 45  ARG 45  48  48  ARG ARG B . n 
B 2 46  ARG 46  49  49  ARG ARG B . n 
B 2 47  THR 47  50  50  THR THR B . n 
B 2 48  LEU 48  51  51  LEU LEU B . n 
B 2 49  ARG 49  52  52  ARG ARG B . n 
B 2 50  GLY 50  53  53  GLY GLY B . n 
B 2 51  HIS 51  54  54  HIS HIS B . n 
B 2 52  LEU 52  55  55  LEU LEU B . n 
B 2 53  ALA 53  56  56  ALA ALA B . n 
B 2 54  LYS 54  57  57  LYS LYS B . n 
B 2 55  ILE 55  58  58  ILE ILE B . n 
B 2 56  TYR 56  59  59  TYR TYR B . n 
B 2 57  ALA 57  60  60  ALA ALA B . n 
B 2 58  MET 58  61  61  MET MET B . n 
B 2 59  HIS 59  62  62  HIS HIS B . n 
B 2 60  TRP 60  63  63  TRP TRP B . n 
B 2 61  GLY 61  64  64  GLY GLY B . n 
B 2 62  THR 62  65  65  THR THR B . n 
B 2 63  ASP 63  66  66  ASP ASP B . n 
B 2 64  SER 64  67  67  SER SER B . n 
B 2 65  ARG 65  68  68  ARG ARG B . n 
B 2 66  LEU 66  69  69  LEU LEU B . n 
B 2 67  LEU 67  70  70  LEU LEU B . n 
B 2 68  VAL 68  71  71  VAL VAL B . n 
B 2 69  SER 69  72  72  SER SER B . n 
B 2 70  ALA 70  73  73  ALA ALA B . n 
B 2 71  SER 71  74  74  SER SER B . n 
B 2 72  GLN 72  75  75  GLN GLN B . n 
B 2 73  ASP 73  76  76  ASP ASP B . n 
B 2 74  GLY 74  77  77  GLY GLY B . n 
B 2 75  LYS 75  78  78  LYS LYS B . n 
B 2 76  LEU 76  79  79  LEU LEU B . n 
B 2 77  ILE 77  80  80  ILE ILE B . n 
B 2 78  ILE 78  81  81  ILE ILE B . n 
B 2 79  TRP 79  82  82  TRP TRP B . n 
B 2 80  ASP 80  83  83  ASP ASP B . n 
B 2 81  SER 81  84  84  SER SER B . n 
B 2 82  TYR 82  85  85  TYR TYR B . n 
B 2 83  THR 83  86  86  THR THR B . n 
B 2 84  THR 84  87  87  THR THR B . n 
B 2 85  ASN 85  88  88  ASN ASN B . n 
B 2 86  LYS 86  89  89  LYS LYS B . n 
B 2 87  VAL 87  90  90  VAL VAL B . n 
B 2 88  HIS 88  91  91  HIS HIS B . n 
B 2 89  ALA 89  92  92  ALA ALA B . n 
B 2 90  ILE 90  93  93  ILE ILE B . n 
B 2 91  PRO 91  94  94  PRO PRO B . n 
B 2 92  LEU 92  95  95  LEU LEU B . n 
B 2 93  ARG 93  96  96  ARG ARG B . n 
B 2 94  SER 94  97  97  SER SER B . n 
B 2 95  SER 95  98  98  SER SER B . n 
B 2 96  TRP 96  99  99  TRP TRP B . n 
B 2 97  VAL 97  100 100 VAL VAL B . n 
B 2 98  MET 98  101 101 MET MET B . n 
B 2 99  THR 99  102 102 THR THR B . n 
B 2 100 CYS 100 103 103 CYS CYS B . n 
B 2 101 ALA 101 104 104 ALA ALA B . n 
B 2 102 TYR 102 105 105 TYR TYR B . n 
B 2 103 ALA 103 106 106 ALA ALA B . n 
B 2 104 PRO 104 107 107 PRO PRO B . n 
B 2 105 SER 105 108 108 SER SER B . n 
B 2 106 GLY 106 109 109 GLY GLY B . n 
B 2 107 ASN 107 110 110 ASN ASN B . n 
B 2 108 TYR 108 111 111 TYR TYR B . n 
B 2 109 VAL 109 112 112 VAL VAL B . n 
B 2 110 ALA 110 113 113 ALA ALA B . n 
B 2 111 CYS 111 114 114 CYS CYS B . n 
B 2 112 GLY 112 115 115 GLY GLY B . n 
B 2 113 GLY 113 116 116 GLY GLY B . n 
B 2 114 LEU 114 117 117 LEU LEU B . n 
B 2 115 ASP 115 118 118 ASP ASP B . n 
B 2 116 ASN 116 119 119 ASN ASN B . n 
B 2 117 ILE 117 120 120 ILE ILE B . n 
B 2 118 CYS 118 121 121 CYS CYS B . n 
B 2 119 SER 119 122 122 SER SER B . n 
B 2 120 ILE 120 123 123 ILE ILE B . n 
B 2 121 TYR 121 124 124 TYR TYR B . n 
B 2 122 ASN 122 125 125 ASN ASN B . n 
B 2 123 LEU 123 126 126 LEU LEU B . n 
B 2 124 LYS 124 127 127 LYS LYS B . n 
B 2 125 THR 125 128 128 THR THR B . n 
B 2 126 ARG 126 129 129 ARG ARG B . n 
B 2 127 GLU 127 130 130 GLU GLU B . n 
B 2 128 GLY 128 131 131 GLY GLY B . n 
B 2 129 ASN 129 132 132 ASN ASN B . n 
B 2 130 VAL 130 133 133 VAL VAL B . n 
B 2 131 ARG 131 134 134 ARG ARG B . n 
B 2 132 VAL 132 135 135 VAL VAL B . n 
B 2 133 SER 133 136 136 SER SER B . n 
B 2 134 ARG 134 137 137 ARG ARG B . n 
B 2 135 GLU 135 138 138 GLU GLU B . n 
B 2 136 LEU 136 139 139 LEU LEU B . n 
B 2 137 ALA 137 140 140 ALA ALA B . n 
B 2 138 GLY 138 141 141 GLY GLY B . n 
B 2 139 HIS 139 142 142 HIS HIS B . n 
B 2 140 THR 140 143 143 THR THR B . n 
B 2 141 GLY 141 144 144 GLY GLY B . n 
B 2 142 TYR 142 145 145 TYR TYR B . n 
B 2 143 LEU 143 146 146 LEU LEU B . n 
B 2 144 SER 144 147 147 SER SER B . n 
B 2 145 CYS 145 148 148 CYS CYS B . n 
B 2 146 CYS 146 149 149 CYS CYS B . n 
B 2 147 ARG 147 150 150 ARG ARG B . n 
B 2 148 PHE 148 151 151 PHE PHE B . n 
B 2 149 LEU 149 152 152 LEU LEU B . n 
B 2 150 ASP 150 153 153 ASP ASP B . n 
B 2 151 ASP 151 154 154 ASP ASP B . n 
B 2 152 ASN 152 155 155 ASN ASN B . n 
B 2 153 GLN 153 156 156 GLN GLN B . n 
B 2 154 ILE 154 157 157 ILE ILE B . n 
B 2 155 VAL 155 158 158 VAL VAL B . n 
B 2 156 THR 156 159 159 THR THR B . n 
B 2 157 SER 157 160 160 SER SER B . n 
B 2 158 SER 158 161 161 SER SER B . n 
B 2 159 GLY 159 162 162 GLY GLY B . n 
B 2 160 ASP 160 163 163 ASP ASP B . n 
B 2 161 THR 161 164 164 THR THR B . n 
B 2 162 THR 162 165 165 THR THR B . n 
B 2 163 CYS 163 166 166 CYS CYS B . n 
B 2 164 ALA 164 167 167 ALA ALA B . n 
B 2 165 LEU 165 168 168 LEU LEU B . n 
B 2 166 TRP 166 169 169 TRP TRP B . n 
B 2 167 ASP 167 170 170 ASP ASP B . n 
B 2 168 ILE 168 171 171 ILE ILE B . n 
B 2 169 GLU 169 172 172 GLU GLU B . n 
B 2 170 THR 170 173 173 THR THR B . n 
B 2 171 GLY 171 174 174 GLY GLY B . n 
B 2 172 GLN 172 175 175 GLN GLN B . n 
B 2 173 GLN 173 176 176 GLN GLN B . n 
B 2 174 THR 174 177 177 THR THR B . n 
B 2 175 THR 175 178 178 THR THR B . n 
B 2 176 THR 176 179 179 THR THR B . n 
B 2 177 PHE 177 180 180 PHE PHE B . n 
B 2 178 THR 178 181 181 THR THR B . n 
B 2 179 GLY 179 182 182 GLY GLY B . n 
B 2 180 HIS 180 183 183 HIS HIS B . n 
B 2 181 THR 181 184 184 THR THR B . n 
B 2 182 GLY 182 185 185 GLY GLY B . n 
B 2 183 ASP 183 186 186 ASP ASP B . n 
B 2 184 VAL 184 187 187 VAL VAL B . n 
B 2 185 MET 185 188 188 MET MET B . n 
B 2 186 SER 186 189 189 SER SER B . n 
B 2 187 LEU 187 190 190 LEU LEU B . n 
B 2 188 SER 188 191 191 SER SER B . n 
B 2 189 LEU 189 192 192 LEU LEU B . n 
B 2 190 ALA 190 193 193 ALA ALA B . n 
B 2 191 PRO 191 194 194 PRO PRO B . n 
B 2 192 ASP 192 195 195 ASP ASP B . n 
B 2 193 THR 193 196 196 THR THR B . n 
B 2 194 ARG 194 197 197 ARG ARG B . n 
B 2 195 LEU 195 198 198 LEU LEU B . n 
B 2 196 PHE 196 199 199 PHE PHE B . n 
B 2 197 VAL 197 200 200 VAL VAL B . n 
B 2 198 SER 198 201 201 SER SER B . n 
B 2 199 GLY 199 202 202 GLY GLY B . n 
B 2 200 ALA 200 203 203 ALA ALA B . n 
B 2 201 CYS 201 204 204 CYS CYS B . n 
B 2 202 ASP 202 205 205 ASP ASP B . n 
B 2 203 ALA 203 206 206 ALA ALA B . n 
B 2 204 SER 204 207 207 SER SER B . n 
B 2 205 ALA 205 208 208 ALA ALA B . n 
B 2 206 LYS 206 209 209 LYS LYS B . n 
B 2 207 LEU 207 210 210 LEU LEU B . n 
B 2 208 TRP 208 211 211 TRP TRP B . n 
B 2 209 ASP 209 212 212 ASP ASP B . n 
B 2 210 VAL 210 213 213 VAL VAL B . n 
B 2 211 ARG 211 214 214 ARG ARG B . n 
B 2 212 GLU 212 215 215 GLU GLU B . n 
B 2 213 GLY 213 216 216 GLY GLY B . n 
B 2 214 MET 214 217 217 MET MET B . n 
B 2 215 CYS 215 218 218 CYS CYS B . n 
B 2 216 ARG 216 219 219 ARG ARG B . n 
B 2 217 GLN 217 220 220 GLN GLN B . n 
B 2 218 THR 218 221 221 THR THR B . n 
B 2 219 PHE 219 222 222 PHE PHE B . n 
B 2 220 THR 220 223 223 THR THR B . n 
B 2 221 GLY 221 224 224 GLY GLY B . n 
B 2 222 HIS 222 225 225 HIS HIS B . n 
B 2 223 GLU 223 226 226 GLU GLU B . n 
B 2 224 SER 224 227 227 SER SER B . n 
B 2 225 ASP 225 228 228 ASP ASP B . n 
B 2 226 ILE 226 229 229 ILE ILE B . n 
B 2 227 ASN 227 230 230 ASN ASN B . n 
B 2 228 ALA 228 231 231 ALA ALA B . n 
B 2 229 ILE 229 232 232 ILE ILE B . n 
B 2 230 CYS 230 233 233 CYS CYS B . n 
B 2 231 PHE 231 234 234 PHE PHE B . n 
B 2 232 PHE 232 235 235 PHE PHE B . n 
B 2 233 PRO 233 236 236 PRO PRO B . n 
B 2 234 ASN 234 237 237 ASN ASN B . n 
B 2 235 GLY 235 238 238 GLY GLY B . n 
B 2 236 ASN 236 239 239 ASN ASN B . n 
B 2 237 ALA 237 240 240 ALA ALA B . n 
B 2 238 PHE 238 241 241 PHE PHE B . n 
B 2 239 ALA 239 242 242 ALA ALA B . n 
B 2 240 THR 240 243 243 THR THR B . n 
B 2 241 GLY 241 244 244 GLY GLY B . n 
B 2 242 SER 242 245 245 SER SER B . n 
B 2 243 ASP 243 246 246 ASP ASP B . n 
B 2 244 ASP 244 247 247 ASP ASP B . n 
B 2 245 ALA 245 248 248 ALA ALA B . n 
B 2 246 THR 246 249 249 THR THR B . n 
B 2 247 CYS 247 250 250 CYS CYS B . n 
B 2 248 ARG 248 251 251 ARG ARG B . n 
B 2 249 LEU 249 252 252 LEU LEU B . n 
B 2 250 PHE 250 253 253 PHE PHE B . n 
B 2 251 ASP 251 254 254 ASP ASP B . n 
B 2 252 LEU 252 255 255 LEU LEU B . n 
B 2 253 ARG 253 256 256 ARG ARG B . n 
B 2 254 ALA 254 257 257 ALA ALA B . n 
B 2 255 ASP 255 258 258 ASP ASP B . n 
B 2 256 GLN 256 259 259 GLN GLN B . n 
B 2 257 GLU 257 260 260 GLU GLU B . n 
B 2 258 LEU 258 261 261 LEU LEU B . n 
B 2 259 MET 259 262 262 MET MET B . n 
B 2 260 THR 260 263 263 THR THR B . n 
B 2 261 TYR 261 264 264 TYR TYR B . n 
B 2 262 SER 262 265 265 SER SER B . n 
B 2 263 HIS 263 266 266 HIS HIS B . n 
B 2 264 ASP 264 267 267 ASP ASP B . n 
B 2 265 ASN 265 268 268 ASN ASN B . n 
B 2 266 ILE 266 269 269 ILE ILE B . n 
B 2 267 ILE 267 270 270 ILE ILE B . n 
B 2 268 CYS 268 271 271 CYS CYS B . n 
B 2 269 GLY 269 272 272 GLY GLY B . n 
B 2 270 ILE 270 273 273 ILE ILE B . n 
B 2 271 THR 271 274 274 THR THR B . n 
B 2 272 SER 272 275 275 SER SER B . n 
B 2 273 VAL 273 276 276 VAL VAL B . n 
B 2 274 SER 274 277 277 SER SER B . n 
B 2 275 PHE 275 278 278 PHE PHE B . n 
B 2 276 SER 276 279 279 SER SER B . n 
B 2 277 LYS 277 280 280 LYS LYS B . n 
B 2 278 SER 278 281 281 SER SER B . n 
B 2 279 GLY 279 282 282 GLY GLY B . n 
B 2 280 ARG 280 283 283 ARG ARG B . n 
B 2 281 LEU 281 284 284 LEU LEU B . n 
B 2 282 LEU 282 285 285 LEU LEU B . n 
B 2 283 LEU 283 286 286 LEU LEU B . n 
B 2 284 ALA 284 287 287 ALA ALA B . n 
B 2 285 GLY 285 288 288 GLY GLY B . n 
B 2 286 TYR 286 289 289 TYR TYR B . n 
B 2 287 ASP 287 290 290 ASP ASP B . n 
B 2 288 ASP 288 291 291 ASP ASP B . n 
B 2 289 PHE 289 292 292 PHE PHE B . n 
B 2 290 ASN 290 293 293 ASN ASN B . n 
B 2 291 CYS 291 294 294 CYS CYS B . n 
B 2 292 ASN 292 295 295 ASN ASN B . n 
B 2 293 VAL 293 296 296 VAL VAL B . n 
B 2 294 TRP 294 297 297 TRP TRP B . n 
B 2 295 ASP 295 298 298 ASP ASP B . n 
B 2 296 ALA 296 299 299 ALA ALA B . n 
B 2 297 LEU 297 300 300 LEU LEU B . n 
B 2 298 LYS 298 301 301 LYS LYS B . n 
B 2 299 ALA 299 302 302 ALA ALA B . n 
B 2 300 ASP 300 303 303 ASP ASP B . n 
B 2 301 ARG 301 304 304 ARG ARG B . n 
B 2 302 ALA 302 305 305 ALA ALA B . n 
B 2 303 GLY 303 306 306 GLY GLY B . n 
B 2 304 VAL 304 307 307 VAL VAL B . n 
B 2 305 LEU 305 308 308 LEU LEU B . n 
B 2 306 ALA 306 309 309 ALA ALA B . n 
B 2 307 GLY 307 310 310 GLY GLY B . n 
B 2 308 HIS 308 311 311 HIS HIS B . n 
B 2 309 ASP 309 312 312 ASP ASP B . n 
B 2 310 ASN 310 313 313 ASN ASN B . n 
B 2 311 ARG 311 314 314 ARG ARG B . n 
B 2 312 VAL 312 315 315 VAL VAL B . n 
B 2 313 SER 313 316 316 SER SER B . n 
B 2 314 CYS 314 317 317 CYS CYS B . n 
B 2 315 LEU 315 318 318 LEU LEU B . n 
B 2 316 GLY 316 319 319 GLY GLY B . n 
B 2 317 VAL 317 320 320 VAL VAL B . n 
B 2 318 THR 318 321 321 THR THR B . n 
B 2 319 ASP 319 322 322 ASP ASP B . n 
B 2 320 ASP 320 323 323 ASP ASP B . n 
B 2 321 GLY 321 324 324 GLY GLY B . n 
B 2 322 MET 322 325 325 MET MET B . n 
B 2 323 ALA 323 326 326 ALA ALA B . n 
B 2 324 VAL 324 327 327 VAL VAL B . n 
B 2 325 ALA 325 328 328 ALA ALA B . n 
B 2 326 THR 326 329 329 THR THR B . n 
B 2 327 GLY 327 330 330 GLY GLY B . n 
B 2 328 SER 328 331 331 SER SER B . n 
B 2 329 TRP 329 332 332 TRP TRP B . n 
B 2 330 ASP 330 333 333 ASP ASP B . n 
B 2 331 SER 331 334 334 SER SER B . n 
B 2 332 PHE 332 335 335 PHE PHE B . n 
B 2 333 LEU 333 336 336 LEU LEU B . n 
B 2 334 LYS 334 337 337 LYS LYS B . n 
B 2 335 ILE 335 338 338 ILE ILE B . n 
B 2 336 TRP 336 339 339 TRP TRP B . n 
B 2 337 ASN 337 340 340 ASN ASN B . n 
C 3 1   SER 1   8   8   SER SER G . n 
C 3 2   ILE 2   9   9   ILE ILE G . n 
C 3 3   ALA 3   10  10  ALA ALA G . n 
C 3 4   GLN 4   11  11  GLN GLN G . n 
C 3 5   ALA 5   12  12  ALA ALA G . n 
C 3 6   ARG 6   13  13  ARG ARG G . n 
C 3 7   LYS 7   14  14  LYS LYS G . n 
C 3 8   LEU 8   15  15  LEU LEU G . n 
C 3 9   VAL 9   16  16  VAL VAL G . n 
C 3 10  GLU 10  17  17  GLU GLU G . n 
C 3 11  GLN 11  18  18  GLN GLN G . n 
C 3 12  LEU 12  19  19  LEU LEU G . n 
C 3 13  LYS 13  20  20  LYS LYS G . n 
C 3 14  MET 14  21  21  MET MET G . n 
C 3 15  GLU 15  22  22  GLU GLU G . n 
C 3 16  ALA 16  23  23  ALA ALA G . n 
C 3 17  ASN 17  24  24  ASN ASN G . n 
C 3 18  ILE 18  25  25  ILE ILE G . n 
C 3 19  ASP 19  26  26  ASP ASP G . n 
C 3 20  ARG 20  27  27  ARG ARG G . n 
C 3 21  ILE 21  28  28  ILE ILE G . n 
C 3 22  LYS 22  29  29  LYS LYS G . n 
C 3 23  VAL 23  30  30  VAL VAL G . n 
C 3 24  SER 24  31  31  SER SER G . n 
C 3 25  LYS 25  32  32  LYS LYS G . n 
C 3 26  ALA 26  33  33  ALA ALA G . n 
C 3 27  ALA 27  34  34  ALA ALA G . n 
C 3 28  ALA 28  35  35  ALA ALA G . n 
C 3 29  ASP 29  36  36  ASP ASP G . n 
C 3 30  LEU 30  37  37  LEU LEU G . n 
C 3 31  MET 31  38  38  MET MET G . n 
C 3 32  ALA 32  39  39  ALA ALA G . n 
C 3 33  TYR 33  40  40  TYR TYR G . n 
C 3 34  CYS 34  41  41  CYS CYS G . n 
C 3 35  GLU 35  42  42  GLU GLU G . n 
C 3 36  ALA 36  43  43  ALA ALA G . n 
C 3 37  HIS 37  44  44  HIS HIS G . n 
C 3 38  ALA 38  45  45  ALA ALA G . n 
C 3 39  LYS 39  46  46  LYS LYS G . n 
C 3 40  GLU 40  47  47  GLU GLU G . n 
C 3 41  ASP 41  48  48  ASP ASP G . n 
C 3 42  PRO 42  49  49  PRO PRO G . n 
C 3 43  LEU 43  50  50  LEU LEU G . n 
C 3 44  LEU 44  51  51  LEU LEU G . n 
C 3 45  THR 45  52  52  THR THR G . n 
C 3 46  PRO 46  53  53  PRO PRO G . n 
C 3 47  VAL 47  54  54  VAL VAL G . n 
C 3 48  PRO 48  55  55  PRO PRO G . n 
C 3 49  ALA 49  56  56  ALA ALA G . n 
C 3 50  SER 50  57  57  SER SER G . n 
C 3 51  GLU 51  58  58  GLU GLU G . n 
C 3 52  ASN 52  59  59  ASN ASN G . n 
C 3 53  PRO 53  60  60  PRO PRO G . n 
C 3 54  PHE 54  61  61  PHE PHE G . n 
C 3 55  ARG 55  62  62  ARG ARG G . n 
C 3 56  GLU 56  63  63  GLU GLU G . n 
D 4 1   ASP 1   1   1   ASP ASP S . n 
D 4 2   VAL 2   2   2   VAL VAL S . n 
D 4 3   GLN 3   3   3   GLN GLN S . n 
D 4 4   LEU 4   4   4   LEU LEU S . n 
D 4 5   VAL 5   5   5   VAL VAL S . n 
D 4 6   GLU 6   6   6   GLU GLU S . n 
D 4 7   SER 7   7   7   SER SER S . n 
D 4 8   GLY 8   8   8   GLY GLY S . n 
D 4 9   GLY 9   9   9   GLY GLY S . n 
D 4 10  GLY 10  10  10  GLY GLY S . n 
D 4 11  LEU 11  11  11  LEU LEU S . n 
D 4 12  VAL 12  12  12  VAL VAL S . n 
D 4 13  GLN 13  13  13  GLN GLN S . n 
D 4 14  PRO 14  14  14  PRO PRO S . n 
D 4 15  GLY 15  15  15  GLY GLY S . n 
D 4 16  GLY 16  16  16  GLY GLY S . n 
D 4 17  SER 17  17  17  SER SER S . n 
D 4 18  ARG 18  18  18  ARG ARG S . n 
D 4 19  LYS 19  19  19  LYS LYS S . n 
D 4 20  LEU 20  20  20  LEU LEU S . n 
D 4 21  SER 21  21  21  SER SER S . n 
D 4 22  CYS 22  22  22  CYS CYS S . n 
D 4 23  SER 23  23  23  SER SER S . n 
D 4 24  ALA 24  24  24  ALA ALA S . n 
D 4 25  SER 25  25  25  SER SER S . n 
D 4 26  GLY 26  26  26  GLY GLY S . n 
D 4 27  PHE 27  27  27  PHE PHE S . n 
D 4 28  ALA 28  28  28  ALA ALA S . n 
D 4 29  PHE 29  29  29  PHE PHE S . n 
D 4 30  SER 30  30  30  SER SER S . n 
D 4 31  SER 31  31  31  SER SER S . n 
D 4 32  PHE 32  32  32  PHE PHE S . n 
D 4 33  GLY 33  33  33  GLY GLY S . n 
D 4 34  MET 34  34  34  MET MET S . n 
D 4 35  HIS 35  35  35  HIS HIS S . n 
D 4 36  TRP 36  36  36  TRP TRP S . n 
D 4 37  VAL 37  37  37  VAL VAL S . n 
D 4 38  ARG 38  38  38  ARG ARG S . n 
D 4 39  GLN 39  39  39  GLN GLN S . n 
D 4 40  ALA 40  40  40  ALA ALA S . n 
D 4 41  PRO 41  41  41  PRO PRO S . n 
D 4 42  GLU 42  42  42  GLU GLU S . n 
D 4 43  LYS 43  43  43  LYS LYS S . n 
D 4 44  GLY 44  44  44  GLY GLY S . n 
D 4 45  LEU 45  45  45  LEU LEU S . n 
D 4 46  GLU 46  46  46  GLU GLU S . n 
D 4 47  TRP 47  47  47  TRP TRP S . n 
D 4 48  VAL 48  48  48  VAL VAL S . n 
D 4 49  ALA 49  49  49  ALA ALA S . n 
D 4 50  TYR 50  50  50  TYR TYR S . n 
D 4 51  ILE 51  51  51  ILE ILE S . n 
D 4 52  SER 52  52  52  SER SER S . n 
D 4 53  SER 53  53  53  SER SER S . n 
D 4 54  GLY 54  54  54  GLY GLY S . n 
D 4 55  SER 55  55  55  SER SER S . n 
D 4 56  GLY 56  56  56  GLY GLY S . n 
D 4 57  THR 57  57  57  THR THR S . n 
D 4 58  ILE 58  58  58  ILE ILE S . n 
D 4 59  TYR 59  59  59  TYR TYR S . n 
D 4 60  TYR 60  60  60  TYR TYR S . n 
D 4 61  ALA 61  61  61  ALA ALA S . n 
D 4 62  ASP 62  62  62  ASP ASP S . n 
D 4 63  THR 63  63  63  THR THR S . n 
D 4 64  VAL 64  64  64  VAL VAL S . n 
D 4 65  LYS 65  65  65  LYS LYS S . n 
D 4 66  GLY 66  66  66  GLY GLY S . n 
D 4 67  ARG 67  67  67  ARG ARG S . n 
D 4 68  PHE 68  68  68  PHE PHE S . n 
D 4 69  THR 69  69  69  THR THR S . n 
D 4 70  ILE 70  70  70  ILE ILE S . n 
D 4 71  SER 71  71  71  SER SER S . n 
D 4 72  ARG 72  72  72  ARG ARG S . n 
D 4 73  ASP 73  73  73  ASP ASP S . n 
D 4 74  ASP 74  74  74  ASP ASP S . n 
D 4 75  PRO 75  75  75  PRO PRO S . n 
D 4 76  LYS 76  76  76  LYS LYS S . n 
D 4 77  ASN 77  77  77  ASN ASN S . n 
D 4 78  THR 78  78  78  THR THR S . n 
D 4 79  LEU 79  79  79  LEU LEU S . n 
D 4 80  PHE 80  80  80  PHE PHE S . n 
D 4 81  LEU 81  81  81  LEU LEU S . n 
D 4 82  GLN 82  82  82  GLN GLN S . n 
D 4 83  MET 83  83  83  MET MET S . n 
D 4 84  THR 84  84  84  THR THR S . n 
D 4 85  SER 85  85  85  SER SER S . n 
D 4 86  LEU 86  86  86  LEU LEU S . n 
D 4 87  ARG 87  87  87  ARG ARG S . n 
D 4 88  SER 88  88  88  SER SER S . n 
D 4 89  GLU 89  89  89  GLU GLU S . n 
D 4 90  ASP 90  90  90  ASP ASP S . n 
D 4 91  THR 91  91  91  THR THR S . n 
D 4 92  ALA 92  92  92  ALA ALA S . n 
D 4 93  MET 93  93  93  MET MET S . n 
D 4 94  TYR 94  94  94  TYR TYR S . n 
D 4 95  TYR 95  95  95  TYR TYR S . n 
D 4 96  CYS 96  96  96  CYS CYS S . n 
D 4 97  VAL 97  97  97  VAL VAL S . n 
D 4 98  ARG 98  98  98  ARG ARG S . n 
D 4 99  SER 99  99  99  SER SER S . n 
D 4 100 ILE 100 100 100 ILE ILE S . n 
D 4 101 TYR 101 101 101 TYR TYR S . n 
D 4 102 TYR 102 102 102 TYR TYR S . n 
D 4 103 TYR 103 103 103 TYR TYR S . n 
D 4 104 GLY 104 104 104 GLY GLY S . n 
D 4 105 SER 105 105 105 SER SER S . n 
D 4 106 SER 106 106 106 SER SER S . n 
D 4 107 PRO 107 107 107 PRO PRO S . n 
D 4 108 PHE 108 108 108 PHE PHE S . n 
D 4 109 ASP 109 109 109 ASP ASP S . n 
D 4 110 PHE 110 110 110 PHE PHE S . n 
D 4 111 TRP 111 111 111 TRP TRP S . n 
D 4 112 GLY 112 112 112 GLY GLY S . n 
D 4 113 GLN 113 113 113 GLN GLN S . n 
D 4 114 GLY 114 114 114 GLY GLY S . n 
D 4 115 THR 115 115 115 THR THR S . n 
D 4 116 THR 116 116 116 THR THR S . n 
D 4 117 LEU 117 117 117 LEU LEU S . n 
D 4 118 THR 118 118 118 THR THR S . n 
D 4 119 VAL 119 119 119 VAL VAL S . n 
D 4 120 SER 120 120 120 SER SER S . n 
D 4 121 SER 121 121 121 SER SER S . n 
D 4 122 GLY 122 122 ?   ?   ?   S . n 
D 4 123 GLY 123 123 ?   ?   ?   S . n 
D 4 124 GLY 124 124 ?   ?   ?   S . n 
D 4 125 GLY 125 125 ?   ?   ?   S . n 
D 4 126 SER 126 126 ?   ?   ?   S . n 
D 4 127 GLY 127 127 ?   ?   ?   S . n 
D 4 128 GLY 128 128 ?   ?   ?   S . n 
D 4 129 GLY 129 129 ?   ?   ?   S . n 
D 4 130 GLY 130 130 ?   ?   ?   S . n 
D 4 131 SER 131 131 ?   ?   ?   S . n 
D 4 132 GLY 132 132 ?   ?   ?   S . n 
D 4 133 GLY 133 133 ?   ?   ?   S . n 
D 4 134 GLY 134 134 ?   ?   ?   S . n 
D 4 135 GLY 135 135 ?   ?   ?   S . n 
D 4 136 SER 136 136 124 SER SER S . n 
D 4 137 ASP 137 137 125 ASP ASP S . n 
D 4 138 ILE 138 138 126 ILE ILE S . n 
D 4 139 VAL 139 139 127 VAL VAL S . n 
D 4 140 MET 140 140 128 MET MET S . n 
D 4 141 THR 141 141 129 THR THR S . n 
D 4 142 GLN 142 142 130 GLN GLN S . n 
D 4 143 ALA 143 143 131 ALA ALA S . n 
D 4 144 THR 144 144 132 THR THR S . n 
D 4 145 SER 145 145 133 SER SER S . n 
D 4 146 SER 146 146 134 SER SER S . n 
D 4 147 VAL 147 147 135 VAL VAL S . n 
D 4 148 PRO 148 148 136 PRO PRO S . n 
D 4 149 VAL 149 149 137 VAL VAL S . n 
D 4 150 THR 150 150 138 THR THR S . n 
D 4 151 PRO 151 151 139 PRO PRO S . n 
D 4 152 GLY 152 152 140 GLY GLY S . n 
D 4 153 GLU 153 153 141 GLU GLU S . n 
D 4 154 SER 154 154 142 SER SER S . n 
D 4 155 VAL 155 155 143 VAL VAL S . n 
D 4 156 SER 156 156 144 SER SER S . n 
D 4 157 ILE 157 157 145 ILE ILE S . n 
D 4 158 SER 158 158 146 SER SER S . n 
D 4 159 CYS 159 159 147 CYS CYS S . n 
D 4 160 ARG 160 160 148 ARG ARG S . n 
D 4 161 SER 161 161 149 SER SER S . n 
D 4 162 SER 162 162 150 SER SER S . n 
D 4 163 LYS 163 163 151 LYS LYS S . n 
D 4 164 SER 164 164 152 SER SER S . n 
D 4 165 LEU 165 165 153 LEU LEU S . n 
D 4 166 LEU 166 166 154 LEU LEU S . n 
D 4 167 HIS 167 167 155 HIS HIS S . n 
D 4 168 SER 168 168 156 SER SER S . n 
D 4 169 ASN 169 169 157 ASN ASN S . n 
D 4 170 GLY 170 170 158 GLY GLY S . n 
D 4 171 ASN 171 171 159 ASN ASN S . n 
D 4 172 THR 172 172 160 THR THR S . n 
D 4 173 TYR 173 173 161 TYR TYR S . n 
D 4 174 LEU 174 174 162 LEU LEU S . n 
D 4 175 TYR 175 175 163 TYR TYR S . n 
D 4 176 TRP 176 176 164 TRP TRP S . n 
D 4 177 PHE 177 177 165 PHE PHE S . n 
D 4 178 LEU 178 178 166 LEU LEU S . n 
D 4 179 GLN 179 179 167 GLN GLN S . n 
D 4 180 ARG 180 180 168 ARG ARG S . n 
D 4 181 PRO 181 181 169 PRO PRO S . n 
D 4 182 GLY 182 182 170 GLY GLY S . n 
D 4 183 GLN 183 183 171 GLN GLN S . n 
D 4 184 SER 184 184 172 SER SER S . n 
D 4 185 PRO 185 185 173 PRO PRO S . n 
D 4 186 GLN 186 186 174 GLN GLN S . n 
D 4 187 LEU 187 187 175 LEU LEU S . n 
D 4 188 LEU 188 188 176 LEU LEU S . n 
D 4 189 ILE 189 189 177 ILE ILE S . n 
D 4 190 TYR 190 190 178 TYR TYR S . n 
D 4 191 ARG 191 191 179 ARG ARG S . n 
D 4 192 MET 192 192 180 MET MET S . n 
D 4 193 SER 193 193 181 SER SER S . n 
D 4 194 ASN 194 194 182 ASN ASN S . n 
D 4 195 LEU 195 195 183 LEU LEU S . n 
D 4 196 ALA 196 196 184 ALA ALA S . n 
D 4 197 SER 197 197 185 SER SER S . n 
D 4 198 GLY 198 198 186 GLY GLY S . n 
D 4 199 VAL 199 199 187 VAL VAL S . n 
D 4 200 PRO 200 200 188 PRO PRO S . n 
D 4 201 ASP 201 201 189 ASP ASP S . n 
D 4 202 ARG 202 202 190 ARG ARG S . n 
D 4 203 PHE 203 203 191 PHE PHE S . n 
D 4 204 SER 204 204 192 SER SER S . n 
D 4 205 GLY 205 205 193 GLY GLY S . n 
D 4 206 SER 206 206 194 SER SER S . n 
D 4 207 GLY 207 207 195 GLY GLY S . n 
D 4 208 SER 208 208 196 SER SER S . n 
D 4 209 GLY 209 209 197 GLY GLY S . n 
D 4 210 THR 210 210 198 THR THR S . n 
D 4 211 ALA 211 211 199 ALA ALA S . n 
D 4 212 PHE 212 212 200 PHE PHE S . n 
D 4 213 THR 213 213 201 THR THR S . n 
D 4 214 LEU 214 214 202 LEU LEU S . n 
D 4 215 THR 215 215 203 THR THR S . n 
D 4 216 ILE 216 216 204 ILE ILE S . n 
D 4 217 SER 217 217 205 SER SER S . n 
D 4 218 ARG 218 218 206 ARG ARG S . n 
D 4 219 LEU 219 219 207 LEU LEU S . n 
D 4 220 GLU 220 220 208 GLU GLU S . n 
D 4 221 ALA 221 221 209 ALA ALA S . n 
D 4 222 GLU 222 222 210 GLU GLU S . n 
D 4 223 ASP 223 223 211 ASP ASP S . n 
D 4 224 VAL 224 224 212 VAL VAL S . n 
D 4 225 GLY 225 225 213 GLY GLY S . n 
D 4 226 VAL 226 226 214 VAL VAL S . n 
D 4 227 TYR 227 227 215 TYR TYR S . n 
D 4 228 TYR 228 228 216 TYR TYR S . n 
D 4 229 CYS 229 229 217 CYS CYS S . n 
D 4 230 MET 230 230 218 MET MET S . n 
D 4 231 GLN 231 231 219 GLN GLN S . n 
D 4 232 HIS 232 232 220 HIS HIS S . n 
D 4 233 LEU 233 233 221 LEU LEU S . n 
D 4 234 GLU 234 234 222 GLU GLU S . n 
D 4 235 TYR 235 235 223 TYR TYR S . n 
D 4 236 PRO 236 236 224 PRO PRO S . n 
D 4 237 LEU 237 237 225 LEU LEU S . n 
D 4 238 THR 238 238 226 THR THR S . n 
D 4 239 PHE 239 239 227 PHE PHE S . n 
D 4 240 GLY 240 240 228 GLY GLY S . n 
D 4 241 ALA 241 241 229 ALA ALA S . n 
D 4 242 GLY 242 242 230 GLY GLY S . n 
D 4 243 THR 243 243 231 THR THR S . n 
D 4 244 LYS 244 244 232 LYS LYS S . n 
D 4 245 LEU 245 245 233 LEU LEU S . n 
D 4 246 GLU 246 246 234 GLU GLU S . n 
D 4 247 LEU 247 247 235 LEU LEU S . n 
E 5 1   MET 1   1   ?   ?   ?   A . n 
E 5 2   ASN 2   2   ?   ?   ?   A . n 
E 5 3   ARG 3   3   ?   ?   ?   A . n 
E 5 4   HIS 4   4   ?   ?   ?   A . n 
E 5 5   HIS 5   5   ?   ?   ?   A . n 
E 5 6   LEU 6   6   ?   ?   ?   A . n 
E 5 7   GLN 7   7   ?   ?   ?   A . n 
E 5 8   ASP 8   8   ?   ?   ?   A . n 
E 5 9   HIS 9   9   ?   ?   ?   A . n 
E 5 10  PHE 10  10  ?   ?   ?   A . n 
E 5 11  LEU 11  11  ?   ?   ?   A . n 
E 5 12  GLU 12  12  ?   ?   ?   A . n 
E 5 13  ILE 13  13  ?   ?   ?   A . n 
E 5 14  ASP 14  14  ?   ?   ?   A . n 
E 5 15  LYS 15  15  ?   ?   ?   A . n 
E 5 16  LYS 16  16  ?   ?   ?   A . n 
E 5 17  ASN 17  17  17  ASN ASN A . n 
E 5 18  CYS 18  18  18  CYS CYS A . n 
E 5 19  CYS 19  19  19  CYS CYS A . n 
E 5 20  VAL 20  20  20  VAL VAL A . n 
E 5 21  PHE 21  21  21  PHE PHE A . n 
E 5 22  ARG 22  22  22  ARG ARG A . n 
E 5 23  ASP 23  23  23  ASP ASP A . n 
E 5 24  ASP 24  24  24  ASP ASP A . n 
E 5 25  PHE 25  25  25  PHE PHE A . n 
E 5 26  ILE 26  26  26  ILE ILE A . n 
E 5 27  ALA 27  27  27  ALA ALA A . n 
E 5 28  LYS 28  28  28  LYS LYS A . n 
E 5 29  VAL 29  29  29  VAL VAL A . n 
E 5 30  LEU 30  30  30  LEU LEU A . n 
E 5 31  PRO 31  31  31  PRO PRO A . n 
E 5 32  PRO 32  32  32  PRO PRO A . n 
E 5 33  VAL 33  33  33  VAL VAL A . n 
E 5 34  LEU 34  34  34  LEU LEU A . n 
E 5 35  GLY 35  35  35  GLY GLY A . n 
E 5 36  LEU 36  36  36  LEU LEU A . n 
E 5 37  GLU 37  37  37  GLU GLU A . n 
E 5 38  PHE 38  38  38  PHE PHE A . n 
E 5 39  ILE 39  39  39  ILE ILE A . n 
E 5 40  PHE 40  40  40  PHE PHE A . n 
E 5 41  GLY 41  41  41  GLY GLY A . n 
E 5 42  LEU 42  42  42  LEU LEU A . n 
E 5 43  LEU 43  43  43  LEU LEU A . n 
E 5 44  GLY 44  44  44  GLY GLY A . n 
E 5 45  ASN 45  45  45  ASN ASN A . n 
E 5 46  GLY 46  46  46  GLY GLY A . n 
E 5 47  LEU 47  47  47  LEU LEU A . n 
E 5 48  ALA 48  48  48  ALA ALA A . n 
E 5 49  LEU 49  49  49  LEU LEU A . n 
E 5 50  TRP 50  50  50  TRP TRP A . n 
E 5 51  ILE 51  51  51  ILE ILE A . n 
E 5 52  PHE 52  52  52  PHE PHE A . n 
E 5 53  CYS 53  53  53  CYS CYS A . n 
E 5 54  PHE 54  54  54  PHE PHE A . n 
E 5 55  HIS 55  55  55  HIS HIS A . n 
E 5 56  LEU 56  56  56  LEU LEU A . n 
E 5 57  LYS 57  57  57  LYS LYS A . n 
E 5 58  SER 58  58  58  SER SER A . n 
E 5 59  TRP 59  59  59  TRP TRP A . n 
E 5 60  LYS 60  60  60  LYS LYS A . n 
E 5 61  SER 61  61  61  SER SER A . n 
E 5 62  SER 62  62  62  SER SER A . n 
E 5 63  ARG 63  63  63  ARG ARG A . n 
E 5 64  ILE 64  64  64  ILE ILE A . n 
E 5 65  PHE 65  65  65  PHE PHE A . n 
E 5 66  LEU 66  66  66  LEU LEU A . n 
E 5 67  PHE 67  67  67  PHE PHE A . n 
E 5 68  ASN 68  68  68  ASN ASN A . n 
E 5 69  LEU 69  69  69  LEU LEU A . n 
E 5 70  ALA 70  70  70  ALA ALA A . n 
E 5 71  VAL 71  71  71  VAL VAL A . n 
E 5 72  ALA 72  72  72  ALA ALA A . n 
E 5 73  ASP 73  73  73  ASP ASP A . n 
E 5 74  PHE 74  74  74  PHE PHE A . n 
E 5 75  LEU 75  75  75  LEU LEU A . n 
E 5 76  LEU 76  76  76  LEU LEU A . n 
E 5 77  ILE 77  77  77  ILE ILE A . n 
E 5 78  ILE 78  78  78  ILE ILE A . n 
E 5 79  CYS 79  79  79  CYS CYS A . n 
E 5 80  LEU 80  80  80  LEU LEU A . n 
E 5 81  PRO 81  81  81  PRO PRO A . n 
E 5 82  PHE 82  82  82  PHE PHE A . n 
E 5 83  VAL 83  83  83  VAL VAL A . n 
E 5 84  MET 84  84  84  MET MET A . n 
E 5 85  ASP 85  85  85  ASP ASP A . n 
E 5 86  TYR 86  86  86  TYR TYR A . n 
E 5 87  TYR 87  87  87  TYR TYR A . n 
E 5 88  VAL 88  88  88  VAL VAL A . n 
E 5 89  ARG 89  89  89  ARG ARG A . n 
E 5 90  ARG 90  90  90  ARG ARG A . n 
E 5 91  SER 91  91  91  SER SER A . n 
E 5 92  ASP 92  92  92  ASP ASP A . n 
E 5 93  TRP 93  93  93  TRP TRP A . n 
E 5 94  LYS 94  94  94  LYS LYS A . n 
E 5 95  PHE 95  95  95  PHE PHE A . n 
E 5 96  GLY 96  96  96  GLY GLY A . n 
E 5 97  ASP 97  97  97  ASP ASP A . n 
E 5 98  ILE 98  98  98  ILE ILE A . n 
E 5 99  PRO 99  99  99  PRO PRO A . n 
E 5 100 CYS 100 100 100 CYS CYS A . n 
E 5 101 ARG 101 101 101 ARG ARG A . n 
E 5 102 LEU 102 102 102 LEU LEU A . n 
E 5 103 VAL 103 103 103 VAL VAL A . n 
E 5 104 LEU 104 104 104 LEU LEU A . n 
E 5 105 PHE 105 105 105 PHE PHE A . n 
E 5 106 MET 106 106 106 MET MET A . n 
E 5 107 PHE 107 107 107 PHE PHE A . n 
E 5 108 ALA 108 108 108 ALA ALA A . n 
E 5 109 MET 109 109 109 MET MET A . n 
E 5 110 ASN 110 110 110 ASN ASN A . n 
E 5 111 ARG 111 111 111 ARG ARG A . n 
E 5 112 GLN 112 112 112 GLN GLN A . n 
E 5 113 GLY 113 113 113 GLY GLY A . n 
E 5 114 SER 114 114 114 SER SER A . n 
E 5 115 ILE 115 115 115 ILE ILE A . n 
E 5 116 ILE 116 116 116 ILE ILE A . n 
E 5 117 PHE 117 117 117 PHE PHE A . n 
E 5 118 LEU 118 118 118 LEU LEU A . n 
E 5 119 THR 119 119 119 THR THR A . n 
E 5 120 VAL 120 120 120 VAL VAL A . n 
E 5 121 VAL 121 121 121 VAL VAL A . n 
E 5 122 ALA 122 122 122 ALA ALA A . n 
E 5 123 VAL 123 123 123 VAL VAL A . n 
E 5 124 ASP 124 124 124 ASP ASP A . n 
E 5 125 ARG 125 125 125 ARG ARG A . n 
E 5 126 TYR 126 126 126 TYR TYR A . n 
E 5 127 PHE 127 127 127 PHE PHE A . n 
E 5 128 ARG 128 128 128 ARG ARG A . n 
E 5 129 VAL 129 129 129 VAL VAL A . n 
E 5 130 VAL 130 130 130 VAL VAL A . n 
E 5 131 HIS 131 131 131 HIS HIS A . n 
E 5 132 PRO 132 132 132 PRO PRO A . n 
E 5 133 HIS 133 133 133 HIS HIS A . n 
E 5 134 HIS 134 134 134 HIS HIS A . n 
E 5 135 ALA 135 135 135 ALA ALA A . n 
E 5 136 LEU 136 136 136 LEU LEU A . n 
E 5 137 ASN 137 137 137 ASN ASN A . n 
E 5 138 LYS 138 138 138 LYS LYS A . n 
E 5 139 ILE 139 139 139 ILE ILE A . n 
E 5 140 SER 140 140 140 SER SER A . n 
E 5 141 ASN 141 141 141 ASN ASN A . n 
E 5 142 TRP 142 142 142 TRP TRP A . n 
E 5 143 THR 143 143 143 THR THR A . n 
E 5 144 ALA 144 144 144 ALA ALA A . n 
E 5 145 ALA 145 145 145 ALA ALA A . n 
E 5 146 ILE 146 146 146 ILE ILE A . n 
E 5 147 ILE 147 147 147 ILE ILE A . n 
E 5 148 SER 148 148 148 SER SER A . n 
E 5 149 CYS 149 149 149 CYS CYS A . n 
E 5 150 LEU 150 150 150 LEU LEU A . n 
E 5 151 LEU 151 151 151 LEU LEU A . n 
E 5 152 TRP 152 152 152 TRP TRP A . n 
E 5 153 GLY 153 153 153 GLY GLY A . n 
E 5 154 ILE 154 154 154 ILE ILE A . n 
E 5 155 THR 155 155 155 THR THR A . n 
E 5 156 VAL 156 156 156 VAL VAL A . n 
E 5 157 GLY 157 157 157 GLY GLY A . n 
E 5 158 LEU 158 158 158 LEU LEU A . n 
E 5 159 THR 159 159 159 THR THR A . n 
E 5 160 VAL 160 160 160 VAL VAL A . n 
E 5 161 HIS 161 161 161 HIS HIS A . n 
E 5 162 LEU 162 162 162 LEU LEU A . n 
E 5 163 LEU 163 163 163 LEU LEU A . n 
E 5 164 LYS 164 164 164 LYS LYS A . n 
E 5 165 LYS 165 165 165 LYS LYS A . n 
E 5 166 LYS 166 166 166 LYS LYS A . n 
E 5 167 LEU 167 167 167 LEU LEU A . n 
E 5 168 LEU 168 168 168 LEU LEU A . n 
E 5 169 ILE 169 169 169 ILE ILE A . n 
E 5 170 GLN 170 170 170 GLN GLN A . n 
E 5 171 ASN 171 171 171 ASN ASN A . n 
E 5 172 GLY 172 172 172 GLY GLY A . n 
E 5 173 THR 173 173 173 THR THR A . n 
E 5 174 ALA 174 174 174 ALA ALA A . n 
E 5 175 ASN 175 175 175 ASN ASN A . n 
E 5 176 VAL 176 176 176 VAL VAL A . n 
E 5 177 CYS 177 177 177 CYS CYS A . n 
E 5 178 ILE 178 178 178 ILE ILE A . n 
E 5 179 SER 179 179 179 SER SER A . n 
E 5 180 PHE 180 180 180 PHE PHE A . n 
E 5 181 SER 181 181 181 SER SER A . n 
E 5 182 ILE 182 182 182 ILE ILE A . n 
E 5 183 CYS 183 183 183 CYS CYS A . n 
E 5 184 HIS 184 184 184 HIS HIS A . n 
E 5 185 THR 185 185 185 THR THR A . n 
E 5 186 PHE 186 186 186 PHE PHE A . n 
E 5 187 ARG 187 187 187 ARG ARG A . n 
E 5 188 TRP 188 188 188 TRP TRP A . n 
E 5 189 HIS 189 189 189 HIS HIS A . n 
E 5 190 GLU 190 190 190 GLU GLU A . n 
E 5 191 ALA 191 191 191 ALA ALA A . n 
E 5 192 MET 192 192 192 MET MET A . n 
E 5 193 PHE 193 193 193 PHE PHE A . n 
E 5 194 LEU 194 194 194 LEU LEU A . n 
E 5 195 LEU 195 195 195 LEU LEU A . n 
E 5 196 GLU 196 196 196 GLU GLU A . n 
E 5 197 PHE 197 197 197 PHE PHE A . n 
E 5 198 PHE 198 198 198 PHE PHE A . n 
E 5 199 LEU 199 199 199 LEU LEU A . n 
E 5 200 PRO 200 200 200 PRO PRO A . n 
E 5 201 LEU 201 201 201 LEU LEU A . n 
E 5 202 GLY 202 202 202 GLY GLY A . n 
E 5 203 ILE 203 203 203 ILE ILE A . n 
E 5 204 ILE 204 204 204 ILE ILE A . n 
E 5 205 LEU 205 205 205 LEU LEU A . n 
E 5 206 PHE 206 206 206 PHE PHE A . n 
E 5 207 CYS 207 207 207 CYS CYS A . n 
E 5 208 SER 208 208 208 SER SER A . n 
E 5 209 ALA 209 209 209 ALA ALA A . n 
E 5 210 ARG 210 210 210 ARG ARG A . n 
E 5 211 ILE 211 211 211 ILE ILE A . n 
E 5 212 ILE 212 212 212 ILE ILE A . n 
E 5 213 TRP 213 213 213 TRP TRP A . n 
E 5 214 SER 214 214 214 SER SER A . n 
E 5 215 LEU 215 215 215 LEU LEU A . n 
E 5 216 ARG 216 216 216 ARG ARG A . n 
E 5 217 GLN 217 217 217 GLN GLN A . n 
E 5 218 ARG 218 218 218 ARG ARG A . n 
E 5 219 GLN 219 219 219 GLN GLN A . n 
E 5 220 MET 220 220 220 MET MET A . n 
E 5 221 ASP 221 221 221 ASP ASP A . n 
E 5 222 ARG 222 222 222 ARG ARG A . n 
E 5 223 HIS 223 223 223 HIS HIS A . n 
E 5 224 ALA 224 224 224 ALA ALA A . n 
E 5 225 LYS 225 225 225 LYS LYS A . n 
E 5 226 ILE 226 226 226 ILE ILE A . n 
E 5 227 LYS 227 227 227 LYS LYS A . n 
E 5 228 ARG 228 228 228 ARG ARG A . n 
E 5 229 ALA 229 229 229 ALA ALA A . n 
E 5 230 ILE 230 230 230 ILE ILE A . n 
E 5 231 THR 231 231 231 THR THR A . n 
E 5 232 PHE 232 232 232 PHE PHE A . n 
E 5 233 ILE 233 233 233 ILE ILE A . n 
E 5 234 MET 234 234 234 MET MET A . n 
E 5 235 VAL 235 235 235 VAL VAL A . n 
E 5 236 VAL 236 236 236 VAL VAL A . n 
E 5 237 ALA 237 237 237 ALA ALA A . n 
E 5 238 ILE 238 238 238 ILE ILE A . n 
E 5 239 VAL 239 239 239 VAL VAL A . n 
E 5 240 PHE 240 240 240 PHE PHE A . n 
E 5 241 VAL 241 241 241 VAL VAL A . n 
E 5 242 ILE 242 242 242 ILE ILE A . n 
E 5 243 CYS 243 243 243 CYS CYS A . n 
E 5 244 PHE 244 244 244 PHE PHE A . n 
E 5 245 LEU 245 245 245 LEU LEU A . n 
E 5 246 PRO 246 246 246 PRO PRO A . n 
E 5 247 SER 247 247 247 SER SER A . n 
E 5 248 VAL 248 248 248 VAL VAL A . n 
E 5 249 VAL 249 249 249 VAL VAL A . n 
E 5 250 VAL 250 250 250 VAL VAL A . n 
E 5 251 ARG 251 251 251 ARG ARG A . n 
E 5 252 ILE 252 252 252 ILE ILE A . n 
E 5 253 HIS 253 253 253 HIS HIS A . n 
E 5 254 ILE 254 254 254 ILE ILE A . n 
E 5 255 PHE 255 255 255 PHE PHE A . n 
E 5 256 TRP 256 256 256 TRP TRP A . n 
E 5 257 LEU 257 257 257 LEU LEU A . n 
E 5 258 LEU 258 258 258 LEU LEU A . n 
E 5 259 HIS 259 259 259 HIS HIS A . n 
E 5 260 THR 260 260 260 THR THR A . n 
E 5 261 SER 261 261 261 SER SER A . n 
E 5 262 GLY 262 262 262 GLY GLY A . n 
E 5 263 THR 263 263 263 THR THR A . n 
E 5 264 GLN 264 264 264 GLN GLN A . n 
E 5 265 ASN 265 265 265 ASN ASN A . n 
E 5 266 CYS 266 266 266 CYS CYS A . n 
E 5 267 GLU 267 267 267 GLU GLU A . n 
E 5 268 VAL 268 268 268 VAL VAL A . n 
E 5 269 TYR 269 269 269 TYR TYR A . n 
E 5 270 ARG 270 270 270 ARG ARG A . n 
E 5 271 SER 271 271 271 SER SER A . n 
E 5 272 VAL 272 272 272 VAL VAL A . n 
E 5 273 ASP 273 273 273 ASP ASP A . n 
E 5 274 LEU 274 274 274 LEU LEU A . n 
E 5 275 ALA 275 275 275 ALA ALA A . n 
E 5 276 PHE 276 276 276 PHE PHE A . n 
E 5 277 PHE 277 277 277 PHE PHE A . n 
E 5 278 ILE 278 278 278 ILE ILE A . n 
E 5 279 THR 279 279 279 THR THR A . n 
E 5 280 LEU 280 280 280 LEU LEU A . n 
E 5 281 SER 281 281 281 SER SER A . n 
E 5 282 PHE 282 282 282 PHE PHE A . n 
E 5 283 THR 283 283 283 THR THR A . n 
E 5 284 TYR 284 284 284 TYR TYR A . n 
E 5 285 MET 285 285 285 MET MET A . n 
E 5 286 ASN 286 286 286 ASN ASN A . n 
E 5 287 SER 287 287 287 SER SER A . n 
E 5 288 MET 288 288 288 MET MET A . n 
E 5 289 LEU 289 289 289 LEU LEU A . n 
E 5 290 ASP 290 290 290 ASP ASP A . n 
E 5 291 PRO 291 291 291 PRO PRO A . n 
E 5 292 VAL 292 292 292 VAL VAL A . n 
E 5 293 VAL 293 293 293 VAL VAL A . n 
E 5 294 TYR 294 294 294 TYR TYR A . n 
E 5 295 TYR 295 295 295 TYR TYR A . n 
E 5 296 PHE 296 296 296 PHE PHE A . n 
E 5 297 SER 297 297 297 SER SER A . n 
E 5 298 SER 298 298 298 SER SER A . n 
E 5 299 PRO 299 299 299 PRO PRO A . n 
E 5 300 SER 300 300 300 SER SER A . n 
E 5 301 PHE 301 301 301 PHE PHE A . n 
E 5 302 PRO 302 302 ?   ?   ?   A . n 
E 5 303 ASN 303 303 ?   ?   ?   A . n 
E 5 304 PHE 304 304 ?   ?   ?   A . n 
E 5 305 PHE 305 305 ?   ?   ?   A . n 
E 5 306 SER 306 306 ?   ?   ?   A . n 
E 5 307 THR 307 307 ?   ?   ?   A . n 
E 5 308 LEU 308 308 ?   ?   ?   A . n 
E 5 309 ILE 309 309 ?   ?   ?   A . n 
E 5 310 ASN 310 310 ?   ?   ?   A . n 
E 5 311 ARG 311 311 ?   ?   ?   A . n 
E 5 312 CYS 312 312 ?   ?   ?   A . n 
E 5 313 LEU 313 313 ?   ?   ?   A . n 
E 5 314 GLN 314 314 ?   ?   ?   A . n 
E 5 315 ARG 315 315 ?   ?   ?   A . n 
E 5 316 LYS 316 316 ?   ?   ?   A . n 
E 5 317 ILE 317 317 ?   ?   ?   A . n 
E 5 318 THR 318 318 ?   ?   ?   A . n 
E 5 319 GLY 319 319 ?   ?   ?   A . n 
E 5 320 GLU 320 320 ?   ?   ?   A . n 
E 5 321 PRO 321 321 ?   ?   ?   A . n 
E 5 322 ASP 322 322 ?   ?   ?   A . n 
E 5 323 ASN 323 323 ?   ?   ?   A . n 
E 5 324 ASN 324 324 ?   ?   ?   A . n 
E 5 325 ARG 325 325 ?   ?   ?   A . n 
E 5 326 SER 326 326 ?   ?   ?   A . n 
E 5 327 THR 327 327 ?   ?   ?   A . n 
E 5 328 SER 328 328 ?   ?   ?   A . n 
E 5 329 VAL 329 329 ?   ?   ?   A . n 
E 5 330 GLU 330 330 ?   ?   ?   A . n 
E 5 331 LEU 331 331 ?   ?   ?   A . n 
E 5 332 THR 332 332 ?   ?   ?   A . n 
E 5 333 GLY 333 333 ?   ?   ?   A . n 
E 5 334 ASP 334 334 ?   ?   ?   A . n 
E 5 335 PRO 335 335 ?   ?   ?   A . n 
E 5 336 ASN 336 336 ?   ?   ?   A . n 
E 5 337 LYS 337 337 ?   ?   ?   A . n 
E 5 338 THR 338 338 ?   ?   ?   A . n 
E 5 339 ARG 339 339 ?   ?   ?   A . n 
E 5 340 GLY 340 340 ?   ?   ?   A . n 
E 5 341 ALA 341 341 ?   ?   ?   A . n 
E 5 342 PRO 342 342 ?   ?   ?   A . n 
E 5 343 GLU 343 343 ?   ?   ?   A . n 
E 5 344 ALA 344 344 ?   ?   ?   A . n 
E 5 345 LEU 345 345 ?   ?   ?   A . n 
E 5 346 ILE 346 346 ?   ?   ?   A . n 
E 5 347 ALA 347 347 ?   ?   ?   A . n 
E 5 348 ASN 348 348 ?   ?   ?   A . n 
E 5 349 SER 349 349 ?   ?   ?   A . n 
E 5 350 GLY 350 350 ?   ?   ?   A . n 
E 5 351 GLU 351 351 ?   ?   ?   A . n 
E 5 352 PRO 352 352 ?   ?   ?   A . n 
E 5 353 TRP 353 353 ?   ?   ?   A . n 
E 5 354 SER 354 354 ?   ?   ?   A . n 
E 5 355 PRO 355 355 ?   ?   ?   A . n 
E 5 356 SER 356 356 ?   ?   ?   A . n 
E 5 357 TYR 357 357 ?   ?   ?   A . n 
E 5 358 LEU 358 358 ?   ?   ?   A . n 
E 5 359 GLY 359 359 ?   ?   ?   A . n 
E 5 360 PRO 360 360 ?   ?   ?   A . n 
E 5 361 THR 361 361 ?   ?   ?   A . n 
E 5 362 SER 362 362 ?   ?   ?   A . n 
E 5 363 ASN 363 363 ?   ?   ?   A . n 
E 5 364 ASN 364 364 ?   ?   ?   A . n 
E 5 365 HIS 365 365 ?   ?   ?   A . n 
E 5 366 SER 366 366 ?   ?   ?   A . n 
E 5 367 LYS 367 367 ?   ?   ?   A . n 
E 5 368 LYS 368 368 ?   ?   ?   A . n 
E 5 369 GLY 369 369 ?   ?   ?   A . n 
E 5 370 HIS 370 370 ?   ?   ?   A . n 
E 5 371 CYS 371 371 ?   ?   ?   A . n 
E 5 372 HIS 372 372 ?   ?   ?   A . n 
E 5 373 GLN 373 373 ?   ?   ?   A . n 
E 5 374 GLU 374 374 ?   ?   ?   A . n 
E 5 375 PRO 375 375 ?   ?   ?   A . n 
E 5 376 ALA 376 376 ?   ?   ?   A . n 
E 5 377 SER 377 377 ?   ?   ?   A . n 
E 5 378 LEU 378 378 ?   ?   ?   A . n 
E 5 379 GLU 379 379 ?   ?   ?   A . n 
E 5 380 LYS 380 380 ?   ?   ?   A . n 
E 5 381 GLN 381 381 ?   ?   ?   A . n 
E 5 382 LEU 382 382 ?   ?   ?   A . n 
E 5 383 GLY 383 383 ?   ?   ?   A . n 
E 5 384 CYS 384 384 ?   ?   ?   A . n 
E 5 385 CYS 385 385 ?   ?   ?   A . n 
E 5 386 ILE 386 386 ?   ?   ?   A . n 
E 5 387 GLU 387 387 ?   ?   ?   A . n 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          CW3 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      CW3 
_pdbx_nonpoly_scheme.auth_mon_id     5C 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 C ASP 193 ? CG  ? A ASP 190 CG  
2   1 Y 1 C ASP 193 ? OD1 ? A ASP 190 OD1 
3   1 Y 1 C ASP 193 ? OD2 ? A ASP 190 OD2 
4   1 Y 1 C ALA 203 ? CB  ? A ALA 200 CB  
5   1 Y 1 C ASP 229 ? CG  ? A ASP 226 CG  
6   1 Y 1 C ASP 229 ? OD1 ? A ASP 226 OD1 
7   1 Y 1 C ASP 229 ? OD2 ? A ASP 226 OD2 
8   1 Y 1 C LEU 232 ? CG  ? A LEU 229 CG  
9   1 Y 1 C LEU 232 ? CD1 ? A LEU 229 CD1 
10  1 Y 1 C LEU 232 ? CD2 ? A LEU 229 CD2 
11  1 Y 1 C VAL 233 ? CG1 ? A VAL 230 CG1 
12  1 Y 1 C VAL 233 ? CG2 ? A VAL 230 CG2 
13  1 Y 1 C ASP 272 ? CG  ? A ASP 269 CG  
14  1 Y 1 C ASP 272 ? OD1 ? A ASP 269 OD1 
15  1 Y 1 C ASP 272 ? OD2 ? A ASP 269 OD2 
16  1 Y 1 C LYS 280 ? CG  ? A LYS 277 CG  
17  1 Y 1 C LYS 280 ? CD  ? A LYS 277 CD  
18  1 Y 1 C LYS 280 ? CE  ? A LYS 277 CE  
19  1 Y 1 C LYS 280 ? NZ  ? A LYS 277 NZ  
20  1 Y 1 C GLU 289 ? CG  ? A GLU 286 CG  
21  1 Y 1 C GLU 289 ? CD  ? A GLU 286 CD  
22  1 Y 1 C GLU 289 ? OE1 ? A GLU 286 OE1 
23  1 Y 1 C GLU 289 ? OE2 ? A GLU 286 OE2 
24  1 Y 1 C GLU 297 ? CG  ? A GLU 294 CG  
25  1 Y 1 C GLU 297 ? CD  ? A GLU 294 CD  
26  1 Y 1 C GLU 297 ? OE1 ? A GLU 294 OE1 
27  1 Y 1 C GLU 297 ? OE2 ? A GLU 294 OE2 
28  1 Y 1 C SER 326 ? OG  ? A SER 323 OG  
29  1 Y 1 C THR 327 ? OG1 ? A THR 324 OG1 
30  1 Y 1 C THR 327 ? CG2 ? A THR 324 CG2 
31  1 Y 1 C PHE 354 ? C   ? A PHE 351 C   
32  1 Y 1 C PHE 354 ? O   ? A PHE 351 O   
33  1 Y 1 B ARG 8   ? CG  ? B ARG 5   CG  
34  1 Y 1 B ARG 8   ? CD  ? B ARG 5   CD  
35  1 Y 1 B ARG 8   ? NE  ? B ARG 5   NE  
36  1 Y 1 B ARG 8   ? CZ  ? B ARG 5   CZ  
37  1 Y 1 B ARG 8   ? NH1 ? B ARG 5   NH1 
38  1 Y 1 B ARG 8   ? NH2 ? B ARG 5   NH2 
39  1 Y 1 B ARG 214 ? CG  ? B ARG 211 CG  
40  1 Y 1 B ARG 214 ? CD  ? B ARG 211 CD  
41  1 Y 1 B ARG 214 ? NE  ? B ARG 211 NE  
42  1 Y 1 B ARG 214 ? CZ  ? B ARG 211 CZ  
43  1 Y 1 B ARG 214 ? NH1 ? B ARG 211 NH1 
44  1 Y 1 B ARG 214 ? NH2 ? B ARG 211 NH2 
45  1 Y 1 B ASP 312 ? CG  ? B ASP 309 CG  
46  1 Y 1 B ASP 312 ? OD1 ? B ASP 309 OD1 
47  1 Y 1 B ASP 312 ? OD2 ? B ASP 309 OD2 
48  1 Y 1 G GLU 63  ? C   ? C GLU 56  C   
49  1 Y 1 G GLU 63  ? O   ? C GLU 56  O   
50  1 Y 1 S SER 17  ? OG  ? D SER 17  OG  
51  1 Y 1 S GLU 42  ? CG  ? D GLU 42  CG  
52  1 Y 1 S GLU 42  ? CD  ? D GLU 42  CD  
53  1 Y 1 S GLU 42  ? OE1 ? D GLU 42  OE1 
54  1 Y 1 S GLU 42  ? OE2 ? D GLU 42  OE2 
55  1 Y 1 S SER 52  ? OG  ? D SER 52  OG  
56  1 Y 1 S ASP 73  ? CG  ? D ASP 73  CG  
57  1 Y 1 S ASP 73  ? OD1 ? D ASP 73  OD1 
58  1 Y 1 S ASP 73  ? OD2 ? D ASP 73  OD2 
59  1 Y 1 S GLU 89  ? CG  ? D GLU 89  CG  
60  1 Y 1 S GLU 89  ? CD  ? D GLU 89  CD  
61  1 Y 1 S GLU 89  ? OE1 ? D GLU 89  OE1 
62  1 Y 1 S GLU 89  ? OE2 ? D GLU 89  OE2 
63  1 Y 1 S SER 121 ? OG  ? D SER 121 OG  
64  1 Y 1 S SER 136 ? OG  ? D SER 136 OG  
65  1 Y 1 S GLU 153 ? CG  ? D GLU 153 CG  
66  1 Y 1 S GLU 153 ? CD  ? D GLU 153 CD  
67  1 Y 1 S GLU 153 ? OE1 ? D GLU 153 OE1 
68  1 Y 1 S GLU 153 ? OE2 ? D GLU 153 OE2 
69  1 Y 1 A ASN 17  ? CG  ? E ASN 17  CG  
70  1 Y 1 A ASN 17  ? OD1 ? E ASN 17  OD1 
71  1 Y 1 A ASN 17  ? ND2 ? E ASN 17  ND2 
72  1 Y 1 A ARG 22  ? CG  ? E ARG 22  CG  
73  1 Y 1 A ARG 22  ? CD  ? E ARG 22  CD  
74  1 Y 1 A ARG 22  ? NE  ? E ARG 22  NE  
75  1 Y 1 A ARG 22  ? CZ  ? E ARG 22  CZ  
76  1 Y 1 A ARG 22  ? NH1 ? E ARG 22  NH1 
77  1 Y 1 A ARG 22  ? NH2 ? E ARG 22  NH2 
78  1 Y 1 A ASP 24  ? CG  ? E ASP 24  CG  
79  1 Y 1 A ASP 24  ? OD1 ? E ASP 24  OD1 
80  1 Y 1 A ASP 24  ? OD2 ? E ASP 24  OD2 
81  1 Y 1 A PHE 25  ? CG  ? E PHE 25  CG  
82  1 Y 1 A PHE 25  ? CD1 ? E PHE 25  CD1 
83  1 Y 1 A PHE 25  ? CD2 ? E PHE 25  CD2 
84  1 Y 1 A PHE 25  ? CE1 ? E PHE 25  CE1 
85  1 Y 1 A PHE 25  ? CE2 ? E PHE 25  CE2 
86  1 Y 1 A PHE 25  ? CZ  ? E PHE 25  CZ  
87  1 Y 1 A LEU 30  ? CG  ? E LEU 30  CG  
88  1 Y 1 A LEU 30  ? CD1 ? E LEU 30  CD1 
89  1 Y 1 A LEU 30  ? CD2 ? E LEU 30  CD2 
90  1 Y 1 A LYS 57  ? CG  ? E LYS 57  CG  
91  1 Y 1 A LYS 57  ? CD  ? E LYS 57  CD  
92  1 Y 1 A LYS 57  ? CE  ? E LYS 57  CE  
93  1 Y 1 A LYS 57  ? NZ  ? E LYS 57  NZ  
94  1 Y 1 A ARG 90  ? CG  ? E ARG 90  CG  
95  1 Y 1 A ARG 90  ? CD  ? E ARG 90  CD  
96  1 Y 1 A ARG 90  ? NE  ? E ARG 90  NE  
97  1 Y 1 A ARG 90  ? CZ  ? E ARG 90  CZ  
98  1 Y 1 A ARG 90  ? NH1 ? E ARG 90  NH1 
99  1 Y 1 A ARG 90  ? NH2 ? E ARG 90  NH2 
100 1 Y 1 A ASP 92  ? CG  ? E ASP 92  CG  
101 1 Y 1 A ASP 92  ? OD1 ? E ASP 92  OD1 
102 1 Y 1 A ASP 92  ? OD2 ? E ASP 92  OD2 
103 1 Y 1 A LYS 94  ? CG  ? E LYS 94  CG  
104 1 Y 1 A LYS 94  ? CD  ? E LYS 94  CD  
105 1 Y 1 A LYS 94  ? CE  ? E LYS 94  CE  
106 1 Y 1 A LYS 94  ? NZ  ? E LYS 94  NZ  
107 1 Y 1 A PHE 95  ? CG  ? E PHE 95  CG  
108 1 Y 1 A PHE 95  ? CD1 ? E PHE 95  CD1 
109 1 Y 1 A PHE 95  ? CD2 ? E PHE 95  CD2 
110 1 Y 1 A PHE 95  ? CE1 ? E PHE 95  CE1 
111 1 Y 1 A PHE 95  ? CE2 ? E PHE 95  CE2 
112 1 Y 1 A PHE 95  ? CZ  ? E PHE 95  CZ  
113 1 Y 1 A LYS 164 ? CG  ? E LYS 164 CG  
114 1 Y 1 A LYS 164 ? CD  ? E LYS 164 CD  
115 1 Y 1 A LYS 164 ? CE  ? E LYS 164 CE  
116 1 Y 1 A LYS 164 ? NZ  ? E LYS 164 NZ  
117 1 Y 1 A LYS 165 ? CG  ? E LYS 165 CG  
118 1 Y 1 A LYS 165 ? CD  ? E LYS 165 CD  
119 1 Y 1 A LYS 165 ? CE  ? E LYS 165 CE  
120 1 Y 1 A LYS 165 ? NZ  ? E LYS 165 NZ  
121 1 Y 1 A LYS 166 ? CG  ? E LYS 166 CG  
122 1 Y 1 A LYS 166 ? CD  ? E LYS 166 CD  
123 1 Y 1 A LYS 166 ? CE  ? E LYS 166 CE  
124 1 Y 1 A LYS 166 ? NZ  ? E LYS 166 NZ  
125 1 Y 1 A LEU 167 ? CG  ? E LEU 167 CG  
126 1 Y 1 A LEU 167 ? CD1 ? E LEU 167 CD1 
127 1 Y 1 A LEU 167 ? CD2 ? E LEU 167 CD2 
128 1 Y 1 A ILE 169 ? CG1 ? E ILE 169 CG1 
129 1 Y 1 A ILE 169 ? CG2 ? E ILE 169 CG2 
130 1 Y 1 A ILE 169 ? CD1 ? E ILE 169 CD1 
131 1 Y 1 A GLN 170 ? CG  ? E GLN 170 CG  
132 1 Y 1 A GLN 170 ? CD  ? E GLN 170 CD  
133 1 Y 1 A GLN 170 ? OE1 ? E GLN 170 OE1 
134 1 Y 1 A GLN 170 ? NE2 ? E GLN 170 NE2 
135 1 Y 1 A ASN 171 ? CG  ? E ASN 171 CG  
136 1 Y 1 A ASN 171 ? OD1 ? E ASN 171 OD1 
137 1 Y 1 A ASN 171 ? ND2 ? E ASN 171 ND2 
138 1 Y 1 A THR 173 ? OG1 ? E THR 173 OG1 
139 1 Y 1 A THR 173 ? CG2 ? E THR 173 CG2 
140 1 Y 1 A HIS 184 ? CG  ? E HIS 184 CG  
141 1 Y 1 A HIS 184 ? ND1 ? E HIS 184 ND1 
142 1 Y 1 A HIS 184 ? CD2 ? E HIS 184 CD2 
143 1 Y 1 A HIS 184 ? CE1 ? E HIS 184 CE1 
144 1 Y 1 A HIS 184 ? NE2 ? E HIS 184 NE2 
145 1 Y 1 A PHE 186 ? CG  ? E PHE 186 CG  
146 1 Y 1 A PHE 186 ? CD1 ? E PHE 186 CD1 
147 1 Y 1 A PHE 186 ? CD2 ? E PHE 186 CD2 
148 1 Y 1 A PHE 186 ? CE1 ? E PHE 186 CE1 
149 1 Y 1 A PHE 186 ? CE2 ? E PHE 186 CE2 
150 1 Y 1 A PHE 186 ? CZ  ? E PHE 186 CZ  
151 1 Y 1 A ARG 187 ? CG  ? E ARG 187 CG  
152 1 Y 1 A ARG 187 ? CD  ? E ARG 187 CD  
153 1 Y 1 A ARG 187 ? NE  ? E ARG 187 NE  
154 1 Y 1 A ARG 187 ? CZ  ? E ARG 187 CZ  
155 1 Y 1 A ARG 187 ? NH1 ? E ARG 187 NH1 
156 1 Y 1 A ARG 187 ? NH2 ? E ARG 187 NH2 
157 1 Y 1 A ILE 238 ? CG1 ? E ILE 238 CG1 
158 1 Y 1 A ILE 238 ? CG2 ? E ILE 238 CG2 
159 1 Y 1 A ILE 238 ? CD1 ? E ILE 238 CD1 
160 1 Y 1 A PHE 255 ? CG  ? E PHE 255 CG  
161 1 Y 1 A PHE 255 ? CD1 ? E PHE 255 CD1 
162 1 Y 1 A PHE 255 ? CD2 ? E PHE 255 CD2 
163 1 Y 1 A PHE 255 ? CE1 ? E PHE 255 CE1 
164 1 Y 1 A PHE 255 ? CE2 ? E PHE 255 CE2 
165 1 Y 1 A PHE 255 ? CZ  ? E PHE 255 CZ  
166 1 Y 1 A THR 263 ? OG1 ? E THR 263 OG1 
167 1 Y 1 A THR 263 ? CG2 ? E THR 263 CG2 
168 1 Y 1 A GLN 264 ? CG  ? E GLN 264 CG  
169 1 Y 1 A GLN 264 ? CD  ? E GLN 264 CD  
170 1 Y 1 A GLN 264 ? OE1 ? E GLN 264 OE1 
171 1 Y 1 A GLN 264 ? NE2 ? E GLN 264 NE2 
172 1 Y 1 A ASN 265 ? CG  ? E ASN 265 CG  
173 1 Y 1 A ASN 265 ? OD1 ? E ASN 265 OD1 
174 1 Y 1 A ASN 265 ? ND2 ? E ASN 265 ND2 
175 1 Y 1 A GLU 267 ? CG  ? E GLU 267 CG  
176 1 Y 1 A GLU 267 ? CD  ? E GLU 267 CD  
177 1 Y 1 A GLU 267 ? OE1 ? E GLU 267 OE1 
178 1 Y 1 A GLU 267 ? OE2 ? E GLU 267 OE2 
179 1 Y 1 A ARG 270 ? CG  ? E ARG 270 CG  
180 1 Y 1 A ARG 270 ? CD  ? E ARG 270 CD  
181 1 Y 1 A ARG 270 ? NE  ? E ARG 270 NE  
182 1 Y 1 A ARG 270 ? CZ  ? E ARG 270 CZ  
183 1 Y 1 A ARG 270 ? NH1 ? E ARG 270 NH1 
184 1 Y 1 A ARG 270 ? NH2 ? E ARG 270 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8JEI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8JEI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8JEI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8JEI 
_struct.title                        'Cryo-EM Structure of the compuond 5c-HCAR3-Gi complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8JEI 
_struct_keywords.text            'complex, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI1_HUMAN P63096 ? 1 
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
4 
2 UNP GBB1_HUMAN  P62873 ? 2 
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
4 
3 UNP GBG2_HUMAN  P59768 ? 3 SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE 8 
4 PDB 8JEI        8JEI   ? 4 ? 1 
5 UNP HCAR3_HUMAN P49019 ? 5 
;MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICL
PFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTV
HLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKITGE
PDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGPTSNNHSKKGHCHQEPASLEKQLGCCIE
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8JEI C 1 ? 351 ? P63096 4 ? 354 ? 4 354 
2 2 8JEI B 1 ? 337 ? P62873 4 ? 340 ? 4 340 
3 3 8JEI G 1 ? 56  ? P59768 8 ? 63  ? 8 63  
4 4 8JEI S 1 ? 247 ? 8JEI   1 ? 247 ? 1 247 
5 5 8JEI A 1 ? 387 ? P49019 1 ? 387 ? 1 387 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8JEI ALA C 200 ? UNP P63096 GLY 203 conflict 203 1 
1 8JEI SER C 323 ? UNP P63096 ALA 326 conflict 326 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 3   ? ARG A 29  ? SER C 6   ARG C 32  1 ? 27 
HELX_P HELX_P2  AA2 GLY A 42  ? MET A 50  ? GLY C 45  MET C 53  1 ? 9  
HELX_P HELX_P3  AA3 GLU A 204 ? GLU A 213 ? GLU C 207 GLU C 216 5 ? 10 
HELX_P HELX_P4  AA4 SER A 225 ? TYR A 227 ? SER C 228 TYR C 230 5 ? 3  
HELX_P HELX_P5  AA5 ARG A 239 ? ASN A 252 ? ARG C 242 ASN C 255 1 ? 14 
HELX_P HELX_P6  AA6 LYS A 267 ? SER A 278 ? LYS C 270 SER C 281 1 ? 12 
HELX_P HELX_P7  AA7 PRO A 279 ? CYS A 283 ? PRO C 282 CYS C 286 5 ? 5  
HELX_P HELX_P8  AA8 ILE A 300 ? LEU A 307 ? ILE C 303 LEU C 310 1 ? 8  
HELX_P HELX_P9  AA9 LYS A 327 ? GLY A 349 ? LYS C 330 GLY C 352 1 ? 23 
HELX_P HELX_P10 AB1 ASP B 2   ? ALA B 21  ? ASP B 5   ALA B 24  1 ? 20 
HELX_P HELX_P11 AB2 THR B 26  ? THR B 31  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P12 AB3 ILE C 2   ? ASN C 17  ? ILE G 9   ASN G 24  1 ? 16 
HELX_P HELX_P13 AB4 LYS C 22  ? HIS C 37  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P14 AB5 ALA C 38  ? ASP C 41  ? ALA G 45  ASP G 48  5 ? 4  
HELX_P HELX_P15 AB6 PRO C 48  ? ASN C 52  ? PRO G 55  ASN G 59  5 ? 5  
HELX_P HELX_P16 AB7 ALA D 28  ? PHE D 32  ? ALA S 28  PHE S 32  5 ? 5  
HELX_P HELX_P17 AB8 SER D 53  ? GLY D 56  ? SER S 53  GLY S 56  5 ? 4  
HELX_P HELX_P18 AB9 ARG D 87  ? THR D 91  ? ARG S 87  THR S 91  5 ? 5  
HELX_P HELX_P19 AC1 ASP E 23  ? GLY E 41  ? ASP A 23  GLY A 41  1 ? 19 
HELX_P HELX_P20 AC2 LEU E 42  ? PHE E 54  ? LEU A 42  PHE A 54  1 ? 13 
HELX_P HELX_P21 AC3 LYS E 60  ? ARG E 89  ? LYS A 60  ARG A 89  1 ? 30 
HELX_P HELX_P22 AC4 GLY E 96  ? HIS E 131 ? GLY A 96  HIS A 131 1 ? 36 
HELX_P HELX_P23 AC5 HIS E 134 ? ILE E 139 ? HIS A 134 ILE A 139 5 ? 6  
HELX_P HELX_P24 AC6 SER E 140 ? LYS E 165 ? SER A 140 LYS A 165 1 ? 26 
HELX_P HELX_P25 AC7 ARG E 187 ? GLU E 196 ? ARG A 187 GLU A 196 1 ? 10 
HELX_P HELX_P26 AC8 PHE E 198 ? ARG E 218 ? PHE A 198 ARG A 218 1 ? 21 
HELX_P HELX_P27 AC9 HIS E 223 ? SER E 261 ? HIS A 223 SER A 261 1 ? 39 
HELX_P HELX_P28 AD1 TYR E 269 ? TYR E 294 ? TYR A 269 TYR A 294 1 ? 26 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? S CYS 22  S CYS 96  1_555 ? ? ? ? ? ? ? 2.035 ? ? 
disulf2 disulf ? ? D CYS 159 SG ? ? ? 1_555 D CYS 229 SG ? ? S CYS 159 S CYS 229 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf3 disulf ? ? E CYS 18  SG ? ? ? 1_555 E CYS 183 SG ? ? A CYS 18  A CYS 183 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4 disulf ? ? E CYS 19  SG ? ? ? 1_555 E CYS 266 SG ? ? A CYS 19  A CYS 266 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf5 disulf ? ? E CYS 100 SG ? ? ? 1_555 E CYS 177 SG ? ? A CYS 100 A CYS 177 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 22  ? CYS D 96  ? CYS S 22  ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 159 ? CYS D 229 ? CYS S 159 ? 1_555 CYS S 229 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 18  ? CYS E 183 ? CYS A 18  ? 1_555 CYS A 183 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS E 19  ? CYS E 266 ? CYS A 19  ? 1_555 CYS A 266 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS E 100 ? CYS E 177 ? CYS A 100 ? 1_555 CYS A 177 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 182 ? PHE A 188 ? VAL C 185 PHE C 191 
AA1 2 LEU A 191 ? ASP A 197 ? LEU C 194 ASP C 200 
AA1 3 VAL A 31  ? GLY A 37  ? VAL C 34  GLY C 40  
AA1 4 ALA A 217 ? ALA A 223 ? ALA C 220 ALA C 226 
AA1 5 SER A 260 ? ASN A 266 ? SER C 263 ASN C 269 
AA1 6 ILE A 316 ? PHE A 320 ? ILE C 319 PHE C 323 
AA2 1 THR B 44  ? LEU B 48  ? THR B 47  LEU B 51  
AA2 2 LEU B 333 ? TRP B 336 ? LEU B 336 TRP B 339 
AA2 3 VAL B 324 ? SER B 328 ? VAL B 327 SER B 331 
AA2 4 VAL B 312 ? VAL B 317 ? VAL B 315 VAL B 320 
AA3 1 ILE B 55  ? TRP B 60  ? ILE B 58  TRP B 63  
AA3 2 LEU B 66  ? SER B 71  ? LEU B 69  SER B 74  
AA3 3 LYS B 75  ? ASP B 80  ? LYS B 78  ASP B 83  
AA3 4 ASN B 85  ? PRO B 91  ? ASN B 88  PRO B 94  
AA4 1 VAL B 97  ? TYR B 102 ? VAL B 100 TYR B 105 
AA4 2 TYR B 108 ? GLY B 113 ? TYR B 111 GLY B 116 
AA4 3 ILE B 117 ? ASN B 122 ? ILE B 120 ASN B 125 
AA4 4 ARG B 131 ? ALA B 137 ? ARG B 134 ALA B 140 
AA5 1 LEU B 143 ? PHE B 148 ? LEU B 146 PHE B 151 
AA5 2 GLN B 153 ? SER B 158 ? GLN B 156 SER B 161 
AA5 3 THR B 162 ? ASP B 167 ? THR B 165 ASP B 170 
AA5 4 GLN B 172 ? THR B 178 ? GLN B 175 THR B 181 
AA6 1 VAL B 184 ? LEU B 189 ? VAL B 187 LEU B 192 
AA6 2 LEU B 195 ? ALA B 200 ? LEU B 198 ALA B 203 
AA6 3 SER B 204 ? ASP B 209 ? SER B 207 ASP B 212 
AA6 4 MET B 214 ? THR B 220 ? MET B 217 THR B 223 
AA7 1 ILE B 226 ? PHE B 231 ? ILE B 229 PHE B 234 
AA7 2 ALA B 237 ? SER B 242 ? ALA B 240 SER B 245 
AA7 3 CYS B 247 ? ASP B 251 ? CYS B 250 ASP B 254 
AA7 4 GLN B 256 ? TYR B 261 ? GLN B 259 TYR B 264 
AA8 1 ILE B 270 ? PHE B 275 ? ILE B 273 PHE B 278 
AA8 2 LEU B 281 ? TYR B 286 ? LEU B 284 TYR B 289 
AA8 3 CYS B 291 ? ASP B 295 ? CYS B 294 ASP B 298 
AA8 4 ARG B 301 ? VAL B 304 ? ARG B 304 VAL B 307 
AA9 1 GLN D 3   ? SER D 7   ? GLN S 3   SER S 7   
AA9 2 SER D 17  ? SER D 25  ? SER S 17  SER S 25  
AA9 3 THR D 78  ? THR D 84  ? THR S 78  THR S 84  
AA9 4 PHE D 68  ? ASP D 73  ? PHE S 68  ASP S 73  
AB1 1 GLY D 10  ? VAL D 12  ? GLY S 10  VAL S 12  
AB1 2 THR D 115 ? VAL D 119 ? THR S 115 VAL S 119 
AB1 3 ALA D 92  ? SER D 99  ? ALA S 92  SER S 99  
AB1 4 GLY D 33  ? GLN D 39  ? GLY S 33  GLN S 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU S 45  ILE S 51  
AB1 6 ILE D 58  ? TYR D 60  ? ILE S 58  TYR S 60  
AB2 1 MET D 140 ? THR D 141 ? MET S 140 THR S 141 
AB2 2 VAL D 155 ? SER D 161 ? VAL S 155 SER S 161 
AB2 3 ALA D 211 ? ILE D 216 ? ALA S 211 ILE S 216 
AB2 4 PHE D 203 ? SER D 208 ? PHE S 203 SER S 208 
AB3 1 SER D 146 ? PRO D 148 ? SER S 146 PRO S 148 
AB3 2 THR D 243 ? GLU D 246 ? THR S 243 GLU S 246 
AB3 3 VAL D 226 ? GLN D 231 ? VAL S 226 GLN S 231 
AB3 4 LEU D 174 ? GLN D 179 ? LEU S 174 GLN S 179 
AB3 5 PRO D 185 ? TYR D 190 ? PRO S 185 TYR S 190 
AB3 6 ASN D 194 ? LEU D 195 ? ASN S 194 LEU S 195 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 186 ? N PHE C 189 O PHE A 193 ? O PHE C 196 
AA1 2 3 O HIS A 192 ? O HIS C 195 N VAL A 31  ? N VAL C 34  
AA1 3 4 N LEU A 36  ? N LEU C 39  O ILE A 219 ? O ILE C 222 
AA1 4 5 N VAL A 222 ? N VAL C 225 O PHE A 264 ? O PHE C 267 
AA1 5 6 N LEU A 263 ? N LEU C 266 O TYR A 317 ? O TYR C 320 
AA2 1 2 N LEU B 48  ? N LEU B 51  O LEU B 333 ? O LEU B 336 
AA2 2 3 O LYS B 334 ? O LYS B 337 N THR B 326 ? N THR B 329 
AA2 3 4 O GLY B 327 ? O GLY B 330 N CYS B 314 ? N CYS B 317 
AA3 1 2 N HIS B 59  ? N HIS B 62  O VAL B 68  ? O VAL B 71  
AA3 2 3 N LEU B 67  ? N LEU B 70  O TRP B 79  ? O TRP B 82  
AA3 3 4 N ASP B 80  ? N ASP B 83  O ASN B 85  ? O ASN B 88  
AA4 1 2 N ALA B 101 ? N ALA B 104 O ALA B 110 ? O ALA B 113 
AA4 2 3 N VAL B 109 ? N VAL B 112 O TYR B 121 ? O TYR B 124 
AA4 3 4 N ILE B 120 ? N ILE B 123 O ARG B 134 ? O ARG B 137 
AA5 1 2 N ARG B 147 ? N ARG B 150 O VAL B 155 ? O VAL B 158 
AA5 2 3 N ILE B 154 ? N ILE B 157 O TRP B 166 ? O TRP B 169 
AA5 3 4 N CYS B 163 ? N CYS B 166 O PHE B 177 ? O PHE B 180 
AA6 1 2 N SER B 188 ? N SER B 191 O VAL B 197 ? O VAL B 200 
AA6 2 3 N PHE B 196 ? N PHE B 199 O TRP B 208 ? O TRP B 211 
AA6 3 4 N ALA B 205 ? N ALA B 208 O PHE B 219 ? O PHE B 222 
AA7 1 2 N CYS B 230 ? N CYS B 233 O ALA B 239 ? O ALA B 242 
AA7 2 3 N THR B 240 ? N THR B 243 O ARG B 248 ? O ARG B 251 
AA7 3 4 N CYS B 247 ? N CYS B 250 O TYR B 261 ? O TYR B 264 
AA8 1 2 N SER B 274 ? N SER B 277 O LEU B 283 ? O LEU B 286 
AA8 2 3 N LEU B 282 ? N LEU B 285 O TRP B 294 ? O TRP B 297 
AA8 3 4 N VAL B 293 ? N VAL B 296 O GLY B 303 ? O GLY B 306 
AA9 1 2 N GLN D 3   ? N GLN S 3   O SER D 25  ? O SER S 25  
AA9 2 3 N ARG D 18  ? N ARG S 18  O MET D 83  ? O MET S 83  
AA9 3 4 O THR D 78  ? O THR S 78  N ASP D 73  ? N ASP S 73  
AB1 1 2 N GLY D 10  ? N GLY S 10  O THR D 118 ? O THR S 118 
AB1 2 3 O LEU D 117 ? O LEU S 117 N ALA D 92  ? N ALA S 92  
AB1 3 4 O VAL D 97  ? O VAL S 97  N HIS D 35  ? N HIS S 35  
AB1 4 5 N MET D 34  ? N MET S 34  O ILE D 51  ? O ILE S 51  
AB1 5 6 N TYR D 50  ? N TYR S 50  O TYR D 59  ? O TYR S 59  
AB2 1 2 N THR D 141 ? N THR S 141 O ARG D 160 ? O ARG S 160 
AB2 2 3 N CYS D 159 ? N CYS S 159 O PHE D 212 ? O PHE S 212 
AB2 3 4 O THR D 215 ? O THR S 215 N SER D 204 ? N SER S 204 
AB3 1 2 N VAL D 147 ? N VAL S 147 O LYS D 244 ? O LYS S 244 
AB3 2 3 O THR D 243 ? O THR S 243 N TYR D 227 ? N TYR S 227 
AB3 3 4 O TYR D 228 ? O TYR S 228 N PHE D 177 ? N PHE S 177 
AB3 4 5 N LEU D 178 ? N LEU S 178 O GLN D 186 ? O GLN S 186 
AB3 5 6 N TYR D 190 ? N TYR S 190 O ASN D 194 ? O ASN S 194 
# 
_pdbx_entry_details.entry_id                   8JEI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG  B SER 245 ? ? OD1 B ASP 247 ? ? 2.13 
2 1 OG1 B THR 274 ? ? O   B VAL 315 ? ? 2.16 
3 1 OG  B SER 331 ? ? OD1 B ASP 333 ? ? 2.17 
4 1 OG  B SER 161 ? ? OD1 B ASP 163 ? ? 2.19 
5 1 OG  B SER 74  ? ? OD1 B ASP 76  ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CB C ALA 299 ? ? CA C ALA 299 ? ? C   C ALA 299 ? ? 92.07  110.10 -18.03 1.50 N 
2  1 N  C ALA 299 ? ? CA C ALA 299 ? ? C   C ALA 299 ? ? 138.57 111.00 27.57  2.70 N 
3  1 N  C ALA 300 ? ? CA C ALA 300 ? ? CB  C ALA 300 ? ? 93.72  110.10 -16.38 1.40 N 
4  1 N  C ALA 300 ? ? CA C ALA 300 ? ? C   C ALA 300 ? ? 85.47  111.00 -25.53 2.70 N 
5  1 CB B ALA 309 ? ? CA B ALA 309 ? ? C   B ALA 309 ? ? 93.80  110.10 -16.30 1.50 N 
6  1 N  B ALA 309 ? ? CA B ALA 309 ? ? C   B ALA 309 ? ? 135.05 111.00 24.05  2.70 N 
7  1 N  B HIS 311 ? ? CA B HIS 311 ? ? CB  B HIS 311 ? ? 98.37  110.60 -12.23 1.80 N 
8  1 N  A CYS 18  ? ? CA A CYS 18  ? ? C   A CYS 18  ? ? 128.93 111.00 17.93  2.70 N 
9  1 CB A ARG 22  ? ? CA A ARG 22  ? ? C   A ARG 22  ? ? 87.16  110.40 -23.24 2.00 N 
10 1 N  A ASP 23  ? ? CA A ASP 23  ? ? CB  A ASP 23  ? ? 88.98  110.60 -21.62 1.80 N 
11 1 N  A ASP 24  ? ? CA A ASP 24  ? ? C   A ASP 24  ? ? 127.65 111.00 16.65  2.70 N 
12 1 NE A ARG 125 ? ? CZ A ARG 125 ? ? NH1 A ARG 125 ? ? 128.05 120.30 7.75   0.50 N 
13 1 NE A ARG 125 ? ? CZ A ARG 125 ? ? NH2 A ARG 125 ? ? 115.91 120.30 -4.39  0.50 N 
14 1 CB A LEU 168 ? ? CA A LEU 168 ? ? C   A LEU 168 ? ? 98.36  110.20 -11.84 1.90 N 
15 1 N  A PHE 186 ? ? CA A PHE 186 ? ? CB  A PHE 186 ? ? 95.43  110.60 -15.17 1.80 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU C 43  ? ? 39.63   41.46   
2  1 PHE C 215 ? ? -91.48  51.18   
3  1 PHE C 259 ? ? -95.41  56.81   
4  1 GLU C 298 ? ? -79.36  -168.86 
5  1 ALA C 299 ? ? 82.47   -10.24  
6  1 ILE C 303 ? ? -123.42 -62.79  
7  1 LYS C 312 ? ? -92.73  45.60   
8  1 ARG C 313 ? ? -143.35 43.99   
9  1 THR B 34  ? ? -95.16  49.17   
10 1 THR B 87  ? ? 58.59   17.14   
11 1 PHE B 292 ? ? 77.38   -1.63   
12 1 GLU S 42  ? ? -140.86 32.18   
13 1 ALA S 143 ? ? 51.59   -123.01 
14 1 THR S 144 ? ? -38.19  121.35  
15 1 MET S 192 ? ? 72.96   -11.16  
16 1 THR S 210 ? ? 77.84   -2.96   
17 1 GLU S 222 ? ? 46.66   24.30   
18 1 CYS A 19  ? ? 2.89    84.03   
19 1 ASP A 92  ? ? -113.11 63.82   
20 1 VAL A 176 ? ? -113.37 78.92   
21 1 PHE A 180 ? ? -87.68  42.44   
22 1 HIS A 184 ? ? 55.91   -137.61 
23 1 THR A 185 ? ? 34.72   157.74  
24 1 GLU A 190 ? ? 72.16   -15.59  
25 1 SER A 261 ? ? -93.06  -62.19  
26 1 ASN A 265 ? ? 71.13   -11.43  
27 1 CYS A 266 ? ? 35.32   58.99   
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    TYR 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     284 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.103 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_validate_main_chain_plane.id 
_pdbx_validate_main_chain_plane.PDB_model_num 
_pdbx_validate_main_chain_plane.auth_comp_id 
_pdbx_validate_main_chain_plane.auth_asym_id 
_pdbx_validate_main_chain_plane.auth_seq_id 
_pdbx_validate_main_chain_plane.PDB_ins_code 
_pdbx_validate_main_chain_plane.label_alt_id 
_pdbx_validate_main_chain_plane.improper_torsion_angle 
1 1 LEU S 233 ? ? -11.14 
2 1 THR A 185 ? ? 10.37  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8JEI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8JEI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.73 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               877365 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM Structure of the compound 5c-HCAR3-Gi complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8JEI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI MORGAGNI' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             1400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8JEI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8JEI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C LYS 54  ? A LYS 51  
2   1 Y 1 C ILE 55  ? A ILE 52  
3   1 Y 1 C ILE 56  ? A ILE 53  
4   1 Y 1 C HIS 57  ? A HIS 54  
5   1 Y 1 C GLU 58  ? A GLU 55  
6   1 Y 1 C ALA 59  ? A ALA 56  
7   1 Y 1 C GLY 60  ? A GLY 57  
8   1 Y 1 C TYR 61  ? A TYR 58  
9   1 Y 1 C SER 62  ? A SER 59  
10  1 Y 1 C GLU 63  ? A GLU 60  
11  1 Y 1 C GLU 64  ? A GLU 61  
12  1 Y 1 C GLU 65  ? A GLU 62  
13  1 Y 1 C CYS 66  ? A CYS 63  
14  1 Y 1 C LYS 67  ? A LYS 64  
15  1 Y 1 C GLN 68  ? A GLN 65  
16  1 Y 1 C TYR 69  ? A TYR 66  
17  1 Y 1 C LYS 70  ? A LYS 67  
18  1 Y 1 C ALA 71  ? A ALA 68  
19  1 Y 1 C VAL 72  ? A VAL 69  
20  1 Y 1 C VAL 73  ? A VAL 70  
21  1 Y 1 C TYR 74  ? A TYR 71  
22  1 Y 1 C SER 75  ? A SER 72  
23  1 Y 1 C ASN 76  ? A ASN 73  
24  1 Y 1 C THR 77  ? A THR 74  
25  1 Y 1 C ILE 78  ? A ILE 75  
26  1 Y 1 C GLN 79  ? A GLN 76  
27  1 Y 1 C SER 80  ? A SER 77  
28  1 Y 1 C ILE 81  ? A ILE 78  
29  1 Y 1 C ILE 82  ? A ILE 79  
30  1 Y 1 C ALA 83  ? A ALA 80  
31  1 Y 1 C ILE 84  ? A ILE 81  
32  1 Y 1 C ILE 85  ? A ILE 82  
33  1 Y 1 C ARG 86  ? A ARG 83  
34  1 Y 1 C ALA 87  ? A ALA 84  
35  1 Y 1 C MET 88  ? A MET 85  
36  1 Y 1 C GLY 89  ? A GLY 86  
37  1 Y 1 C ARG 90  ? A ARG 87  
38  1 Y 1 C LEU 91  ? A LEU 88  
39  1 Y 1 C LYS 92  ? A LYS 89  
40  1 Y 1 C ILE 93  ? A ILE 90  
41  1 Y 1 C ASP 94  ? A ASP 91  
42  1 Y 1 C PHE 95  ? A PHE 92  
43  1 Y 1 C GLY 96  ? A GLY 93  
44  1 Y 1 C ASP 97  ? A ASP 94  
45  1 Y 1 C SER 98  ? A SER 95  
46  1 Y 1 C ALA 99  ? A ALA 96  
47  1 Y 1 C ARG 100 ? A ARG 97  
48  1 Y 1 C ALA 101 ? A ALA 98  
49  1 Y 1 C ASP 102 ? A ASP 99  
50  1 Y 1 C ASP 103 ? A ASP 100 
51  1 Y 1 C ALA 104 ? A ALA 101 
52  1 Y 1 C ARG 105 ? A ARG 102 
53  1 Y 1 C GLN 106 ? A GLN 103 
54  1 Y 1 C LEU 107 ? A LEU 104 
55  1 Y 1 C PHE 108 ? A PHE 105 
56  1 Y 1 C VAL 109 ? A VAL 106 
57  1 Y 1 C LEU 110 ? A LEU 107 
58  1 Y 1 C ALA 111 ? A ALA 108 
59  1 Y 1 C GLY 112 ? A GLY 109 
60  1 Y 1 C ALA 113 ? A ALA 110 
61  1 Y 1 C ALA 114 ? A ALA 111 
62  1 Y 1 C GLU 115 ? A GLU 112 
63  1 Y 1 C GLU 116 ? A GLU 113 
64  1 Y 1 C GLY 117 ? A GLY 114 
65  1 Y 1 C PHE 118 ? A PHE 115 
66  1 Y 1 C MET 119 ? A MET 116 
67  1 Y 1 C THR 120 ? A THR 117 
68  1 Y 1 C ALA 121 ? A ALA 118 
69  1 Y 1 C GLU 122 ? A GLU 119 
70  1 Y 1 C LEU 123 ? A LEU 120 
71  1 Y 1 C ALA 124 ? A ALA 121 
72  1 Y 1 C GLY 125 ? A GLY 122 
73  1 Y 1 C VAL 126 ? A VAL 123 
74  1 Y 1 C ILE 127 ? A ILE 124 
75  1 Y 1 C LYS 128 ? A LYS 125 
76  1 Y 1 C ARG 129 ? A ARG 126 
77  1 Y 1 C LEU 130 ? A LEU 127 
78  1 Y 1 C TRP 131 ? A TRP 128 
79  1 Y 1 C LYS 132 ? A LYS 129 
80  1 Y 1 C ASP 133 ? A ASP 130 
81  1 Y 1 C SER 134 ? A SER 131 
82  1 Y 1 C GLY 135 ? A GLY 132 
83  1 Y 1 C VAL 136 ? A VAL 133 
84  1 Y 1 C GLN 137 ? A GLN 134 
85  1 Y 1 C ALA 138 ? A ALA 135 
86  1 Y 1 C CYS 139 ? A CYS 136 
87  1 Y 1 C PHE 140 ? A PHE 137 
88  1 Y 1 C ASN 141 ? A ASN 138 
89  1 Y 1 C ARG 142 ? A ARG 139 
90  1 Y 1 C SER 143 ? A SER 140 
91  1 Y 1 C ARG 144 ? A ARG 141 
92  1 Y 1 C GLU 145 ? A GLU 142 
93  1 Y 1 C TYR 146 ? A TYR 143 
94  1 Y 1 C GLN 147 ? A GLN 144 
95  1 Y 1 C LEU 148 ? A LEU 145 
96  1 Y 1 C ASN 149 ? A ASN 146 
97  1 Y 1 C ASP 150 ? A ASP 147 
98  1 Y 1 C SER 151 ? A SER 148 
99  1 Y 1 C ALA 152 ? A ALA 149 
100 1 Y 1 C ALA 153 ? A ALA 150 
101 1 Y 1 C TYR 154 ? A TYR 151 
102 1 Y 1 C TYR 155 ? A TYR 152 
103 1 Y 1 C LEU 156 ? A LEU 153 
104 1 Y 1 C ASN 157 ? A ASN 154 
105 1 Y 1 C ASP 158 ? A ASP 155 
106 1 Y 1 C LEU 159 ? A LEU 156 
107 1 Y 1 C ASP 160 ? A ASP 157 
108 1 Y 1 C ARG 161 ? A ARG 158 
109 1 Y 1 C ILE 162 ? A ILE 159 
110 1 Y 1 C ALA 163 ? A ALA 160 
111 1 Y 1 C GLN 164 ? A GLN 161 
112 1 Y 1 C PRO 165 ? A PRO 162 
113 1 Y 1 C ASN 166 ? A ASN 163 
114 1 Y 1 C TYR 167 ? A TYR 164 
115 1 Y 1 C ILE 168 ? A ILE 165 
116 1 Y 1 C PRO 169 ? A PRO 166 
117 1 Y 1 C THR 170 ? A THR 167 
118 1 Y 1 C GLN 171 ? A GLN 168 
119 1 Y 1 C GLN 172 ? A GLN 169 
120 1 Y 1 C ASP 173 ? A ASP 170 
121 1 Y 1 C VAL 174 ? A VAL 171 
122 1 Y 1 C LEU 175 ? A LEU 172 
123 1 Y 1 C ARG 176 ? A ARG 173 
124 1 Y 1 C THR 177 ? A THR 174 
125 1 Y 1 C ARG 178 ? A ARG 175 
126 1 Y 1 C VAL 179 ? A VAL 176 
127 1 Y 1 C LYS 180 ? A LYS 177 
128 1 Y 1 C THR 181 ? A THR 178 
129 1 Y 1 C LEU 234 ? A LEU 231 
130 1 Y 1 C ALA 235 ? A ALA 232 
131 1 Y 1 C GLU 236 ? A GLU 233 
132 1 Y 1 C ASP 237 ? A ASP 234 
133 1 Y 1 C GLU 238 ? A GLU 235 
134 1 Y 1 C GLU 239 ? A GLU 236 
135 1 Y 1 C MET 240 ? A MET 237 
136 1 Y 1 S GLY 122 ? D GLY 122 
137 1 Y 1 S GLY 123 ? D GLY 123 
138 1 Y 1 S GLY 124 ? D GLY 124 
139 1 Y 1 S GLY 125 ? D GLY 125 
140 1 Y 1 S SER 126 ? D SER 126 
141 1 Y 1 S GLY 127 ? D GLY 127 
142 1 Y 1 S GLY 128 ? D GLY 128 
143 1 Y 1 S GLY 129 ? D GLY 129 
144 1 Y 1 S GLY 130 ? D GLY 130 
145 1 Y 1 S SER 131 ? D SER 131 
146 1 Y 1 S GLY 132 ? D GLY 132 
147 1 Y 1 S GLY 133 ? D GLY 133 
148 1 Y 1 S GLY 134 ? D GLY 134 
149 1 Y 1 S GLY 135 ? D GLY 135 
150 1 Y 1 A MET 1   ? E MET 1   
151 1 Y 1 A ASN 2   ? E ASN 2   
152 1 Y 1 A ARG 3   ? E ARG 3   
153 1 Y 1 A HIS 4   ? E HIS 4   
154 1 Y 1 A HIS 5   ? E HIS 5   
155 1 Y 1 A LEU 6   ? E LEU 6   
156 1 Y 1 A GLN 7   ? E GLN 7   
157 1 Y 1 A ASP 8   ? E ASP 8   
158 1 Y 1 A HIS 9   ? E HIS 9   
159 1 Y 1 A PHE 10  ? E PHE 10  
160 1 Y 1 A LEU 11  ? E LEU 11  
161 1 Y 1 A GLU 12  ? E GLU 12  
162 1 Y 1 A ILE 13  ? E ILE 13  
163 1 Y 1 A ASP 14  ? E ASP 14  
164 1 Y 1 A LYS 15  ? E LYS 15  
165 1 Y 1 A LYS 16  ? E LYS 16  
166 1 Y 1 A PRO 302 ? E PRO 302 
167 1 Y 1 A ASN 303 ? E ASN 303 
168 1 Y 1 A PHE 304 ? E PHE 304 
169 1 Y 1 A PHE 305 ? E PHE 305 
170 1 Y 1 A SER 306 ? E SER 306 
171 1 Y 1 A THR 307 ? E THR 307 
172 1 Y 1 A LEU 308 ? E LEU 308 
173 1 Y 1 A ILE 309 ? E ILE 309 
174 1 Y 1 A ASN 310 ? E ASN 310 
175 1 Y 1 A ARG 311 ? E ARG 311 
176 1 Y 1 A CYS 312 ? E CYS 312 
177 1 Y 1 A LEU 313 ? E LEU 313 
178 1 Y 1 A GLN 314 ? E GLN 314 
179 1 Y 1 A ARG 315 ? E ARG 315 
180 1 Y 1 A LYS 316 ? E LYS 316 
181 1 Y 1 A ILE 317 ? E ILE 317 
182 1 Y 1 A THR 318 ? E THR 318 
183 1 Y 1 A GLY 319 ? E GLY 319 
184 1 Y 1 A GLU 320 ? E GLU 320 
185 1 Y 1 A PRO 321 ? E PRO 321 
186 1 Y 1 A ASP 322 ? E ASP 322 
187 1 Y 1 A ASN 323 ? E ASN 323 
188 1 Y 1 A ASN 324 ? E ASN 324 
189 1 Y 1 A ARG 325 ? E ARG 325 
190 1 Y 1 A SER 326 ? E SER 326 
191 1 Y 1 A THR 327 ? E THR 327 
192 1 Y 1 A SER 328 ? E SER 328 
193 1 Y 1 A VAL 329 ? E VAL 329 
194 1 Y 1 A GLU 330 ? E GLU 330 
195 1 Y 1 A LEU 331 ? E LEU 331 
196 1 Y 1 A THR 332 ? E THR 332 
197 1 Y 1 A GLY 333 ? E GLY 333 
198 1 Y 1 A ASP 334 ? E ASP 334 
199 1 Y 1 A PRO 335 ? E PRO 335 
200 1 Y 1 A ASN 336 ? E ASN 336 
201 1 Y 1 A LYS 337 ? E LYS 337 
202 1 Y 1 A THR 338 ? E THR 338 
203 1 Y 1 A ARG 339 ? E ARG 339 
204 1 Y 1 A GLY 340 ? E GLY 340 
205 1 Y 1 A ALA 341 ? E ALA 341 
206 1 Y 1 A PRO 342 ? E PRO 342 
207 1 Y 1 A GLU 343 ? E GLU 343 
208 1 Y 1 A ALA 344 ? E ALA 344 
209 1 Y 1 A LEU 345 ? E LEU 345 
210 1 Y 1 A ILE 346 ? E ILE 346 
211 1 Y 1 A ALA 347 ? E ALA 347 
212 1 Y 1 A ASN 348 ? E ASN 348 
213 1 Y 1 A SER 349 ? E SER 349 
214 1 Y 1 A GLY 350 ? E GLY 350 
215 1 Y 1 A GLU 351 ? E GLU 351 
216 1 Y 1 A PRO 352 ? E PRO 352 
217 1 Y 1 A TRP 353 ? E TRP 353 
218 1 Y 1 A SER 354 ? E SER 354 
219 1 Y 1 A PRO 355 ? E PRO 355 
220 1 Y 1 A SER 356 ? E SER 356 
221 1 Y 1 A TYR 357 ? E TYR 357 
222 1 Y 1 A LEU 358 ? E LEU 358 
223 1 Y 1 A GLY 359 ? E GLY 359 
224 1 Y 1 A PRO 360 ? E PRO 360 
225 1 Y 1 A THR 361 ? E THR 361 
226 1 Y 1 A SER 362 ? E SER 362 
227 1 Y 1 A ASN 363 ? E ASN 363 
228 1 Y 1 A ASN 364 ? E ASN 364 
229 1 Y 1 A HIS 365 ? E HIS 365 
230 1 Y 1 A SER 366 ? E SER 366 
231 1 Y 1 A LYS 367 ? E LYS 367 
232 1 Y 1 A LYS 368 ? E LYS 368 
233 1 Y 1 A GLY 369 ? E GLY 369 
234 1 Y 1 A HIS 370 ? E HIS 370 
235 1 Y 1 A CYS 371 ? E CYS 371 
236 1 Y 1 A HIS 372 ? E HIS 372 
237 1 Y 1 A GLN 373 ? E GLN 373 
238 1 Y 1 A GLU 374 ? E GLU 374 
239 1 Y 1 A PRO 375 ? E PRO 375 
240 1 Y 1 A ALA 376 ? E ALA 376 
241 1 Y 1 A SER 377 ? E SER 377 
242 1 Y 1 A LEU 378 ? E LEU 378 
243 1 Y 1 A GLU 379 ? E GLU 379 
244 1 Y 1 A LYS 380 ? E LYS 380 
245 1 Y 1 A GLN 381 ? E GLN 381 
246 1 Y 1 A LEU 382 ? E LEU 382 
247 1 Y 1 A GLY 383 ? E GLY 383 
248 1 Y 1 A CYS 384 ? E CYS 384 
249 1 Y 1 A CYS 385 ? E CYS 385 
250 1 Y 1 A ILE 386 ? E ILE 386 
251 1 Y 1 A GLU 387 ? E GLU 387 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CW3 C01  C N N 74  
CW3 C02  C N N 75  
CW3 C03  C N N 76  
CW3 N04  N N N 77  
CW3 C05  C Y N 78  
CW3 C06  C Y N 79  
CW3 C07  C Y N 80  
CW3 C08  C Y N 81  
CW3 C09  C Y N 82  
CW3 C10  C Y N 83  
CW3 N11  N N N 84  
CW3 O12  O N N 85  
CW3 O13  O N N 86  
CW3 C14  C N N 87  
CW3 O15  O N N 88  
CW3 O16  O N N 89  
CW3 H1   H N N 90  
CW3 H2   H N N 91  
CW3 H3   H N N 92  
CW3 H4   H N N 93  
CW3 H5   H N N 94  
CW3 H6   H N N 95  
CW3 H7   H N N 96  
CW3 H8   H N N 97  
CW3 H9   H N N 98  
CW3 H10  H N N 99  
CW3 H11  H N N 100 
CW3 H12  H N N 101 
CYS N    N N N 102 
CYS CA   C N R 103 
CYS C    C N N 104 
CYS O    O N N 105 
CYS CB   C N N 106 
CYS SG   S N N 107 
CYS OXT  O N N 108 
CYS H    H N N 109 
CYS H2   H N N 110 
CYS HA   H N N 111 
CYS HB2  H N N 112 
CYS HB3  H N N 113 
CYS HG   H N N 114 
CYS HXT  H N N 115 
GLN N    N N N 116 
GLN CA   C N S 117 
GLN C    C N N 118 
GLN O    O N N 119 
GLN CB   C N N 120 
GLN CG   C N N 121 
GLN CD   C N N 122 
GLN OE1  O N N 123 
GLN NE2  N N N 124 
GLN OXT  O N N 125 
GLN H    H N N 126 
GLN H2   H N N 127 
GLN HA   H N N 128 
GLN HB2  H N N 129 
GLN HB3  H N N 130 
GLN HG2  H N N 131 
GLN HG3  H N N 132 
GLN HE21 H N N 133 
GLN HE22 H N N 134 
GLN HXT  H N N 135 
GLU N    N N N 136 
GLU CA   C N S 137 
GLU C    C N N 138 
GLU O    O N N 139 
GLU CB   C N N 140 
GLU CG   C N N 141 
GLU CD   C N N 142 
GLU OE1  O N N 143 
GLU OE2  O N N 144 
GLU OXT  O N N 145 
GLU H    H N N 146 
GLU H2   H N N 147 
GLU HA   H N N 148 
GLU HB2  H N N 149 
GLU HB3  H N N 150 
GLU HG2  H N N 151 
GLU HG3  H N N 152 
GLU HE2  H N N 153 
GLU HXT  H N N 154 
GLY N    N N N 155 
GLY CA   C N N 156 
GLY C    C N N 157 
GLY O    O N N 158 
GLY OXT  O N N 159 
GLY H    H N N 160 
GLY H2   H N N 161 
GLY HA2  H N N 162 
GLY HA3  H N N 163 
GLY HXT  H N N 164 
HIS N    N N N 165 
HIS CA   C N S 166 
HIS C    C N N 167 
HIS O    O N N 168 
HIS CB   C N N 169 
HIS CG   C Y N 170 
HIS ND1  N Y N 171 
HIS CD2  C Y N 172 
HIS CE1  C Y N 173 
HIS NE2  N Y N 174 
HIS OXT  O N N 175 
HIS H    H N N 176 
HIS H2   H N N 177 
HIS HA   H N N 178 
HIS HB2  H N N 179 
HIS HB3  H N N 180 
HIS HD1  H N N 181 
HIS HD2  H N N 182 
HIS HE1  H N N 183 
HIS HE2  H N N 184 
HIS HXT  H N N 185 
ILE N    N N N 186 
ILE CA   C N S 187 
ILE C    C N N 188 
ILE O    O N N 189 
ILE CB   C N S 190 
ILE CG1  C N N 191 
ILE CG2  C N N 192 
ILE CD1  C N N 193 
ILE OXT  O N N 194 
ILE H    H N N 195 
ILE H2   H N N 196 
ILE HA   H N N 197 
ILE HB   H N N 198 
ILE HG12 H N N 199 
ILE HG13 H N N 200 
ILE HG21 H N N 201 
ILE HG22 H N N 202 
ILE HG23 H N N 203 
ILE HD11 H N N 204 
ILE HD12 H N N 205 
ILE HD13 H N N 206 
ILE HXT  H N N 207 
LEU N    N N N 208 
LEU CA   C N S 209 
LEU C    C N N 210 
LEU O    O N N 211 
LEU CB   C N N 212 
LEU CG   C N N 213 
LEU CD1  C N N 214 
LEU CD2  C N N 215 
LEU OXT  O N N 216 
LEU H    H N N 217 
LEU H2   H N N 218 
LEU HA   H N N 219 
LEU HB2  H N N 220 
LEU HB3  H N N 221 
LEU HG   H N N 222 
LEU HD11 H N N 223 
LEU HD12 H N N 224 
LEU HD13 H N N 225 
LEU HD21 H N N 226 
LEU HD22 H N N 227 
LEU HD23 H N N 228 
LEU HXT  H N N 229 
LYS N    N N N 230 
LYS CA   C N S 231 
LYS C    C N N 232 
LYS O    O N N 233 
LYS CB   C N N 234 
LYS CG   C N N 235 
LYS CD   C N N 236 
LYS CE   C N N 237 
LYS NZ   N N N 238 
LYS OXT  O N N 239 
LYS H    H N N 240 
LYS H2   H N N 241 
LYS HA   H N N 242 
LYS HB2  H N N 243 
LYS HB3  H N N 244 
LYS HG2  H N N 245 
LYS HG3  H N N 246 
LYS HD2  H N N 247 
LYS HD3  H N N 248 
LYS HE2  H N N 249 
LYS HE3  H N N 250 
LYS HZ1  H N N 251 
LYS HZ2  H N N 252 
LYS HZ3  H N N 253 
LYS HXT  H N N 254 
MET N    N N N 255 
MET CA   C N S 256 
MET C    C N N 257 
MET O    O N N 258 
MET CB   C N N 259 
MET CG   C N N 260 
MET SD   S N N 261 
MET CE   C N N 262 
MET OXT  O N N 263 
MET H    H N N 264 
MET H2   H N N 265 
MET HA   H N N 266 
MET HB2  H N N 267 
MET HB3  H N N 268 
MET HG2  H N N 269 
MET HG3  H N N 270 
MET HE1  H N N 271 
MET HE2  H N N 272 
MET HE3  H N N 273 
MET HXT  H N N 274 
PHE N    N N N 275 
PHE CA   C N S 276 
PHE C    C N N 277 
PHE O    O N N 278 
PHE CB   C N N 279 
PHE CG   C Y N 280 
PHE CD1  C Y N 281 
PHE CD2  C Y N 282 
PHE CE1  C Y N 283 
PHE CE2  C Y N 284 
PHE CZ   C Y N 285 
PHE OXT  O N N 286 
PHE H    H N N 287 
PHE H2   H N N 288 
PHE HA   H N N 289 
PHE HB2  H N N 290 
PHE HB3  H N N 291 
PHE HD1  H N N 292 
PHE HD2  H N N 293 
PHE HE1  H N N 294 
PHE HE2  H N N 295 
PHE HZ   H N N 296 
PHE HXT  H N N 297 
PRO N    N N N 298 
PRO CA   C N S 299 
PRO C    C N N 300 
PRO O    O N N 301 
PRO CB   C N N 302 
PRO CG   C N N 303 
PRO CD   C N N 304 
PRO OXT  O N N 305 
PRO H    H N N 306 
PRO HA   H N N 307 
PRO HB2  H N N 308 
PRO HB3  H N N 309 
PRO HG2  H N N 310 
PRO HG3  H N N 311 
PRO HD2  H N N 312 
PRO HD3  H N N 313 
PRO HXT  H N N 314 
SER N    N N N 315 
SER CA   C N S 316 
SER C    C N N 317 
SER O    O N N 318 
SER CB   C N N 319 
SER OG   O N N 320 
SER OXT  O N N 321 
SER H    H N N 322 
SER H2   H N N 323 
SER HA   H N N 324 
SER HB2  H N N 325 
SER HB3  H N N 326 
SER HG   H N N 327 
SER HXT  H N N 328 
THR N    N N N 329 
THR CA   C N S 330 
THR C    C N N 331 
THR O    O N N 332 
THR CB   C N R 333 
THR OG1  O N N 334 
THR CG2  C N N 335 
THR OXT  O N N 336 
THR H    H N N 337 
THR H2   H N N 338 
THR HA   H N N 339 
THR HB   H N N 340 
THR HG1  H N N 341 
THR HG21 H N N 342 
THR HG22 H N N 343 
THR HG23 H N N 344 
THR HXT  H N N 345 
TRP N    N N N 346 
TRP CA   C N S 347 
TRP C    C N N 348 
TRP O    O N N 349 
TRP CB   C N N 350 
TRP CG   C Y N 351 
TRP CD1  C Y N 352 
TRP CD2  C Y N 353 
TRP NE1  N Y N 354 
TRP CE2  C Y N 355 
TRP CE3  C Y N 356 
TRP CZ2  C Y N 357 
TRP CZ3  C Y N 358 
TRP CH2  C Y N 359 
TRP OXT  O N N 360 
TRP H    H N N 361 
TRP H2   H N N 362 
TRP HA   H N N 363 
TRP HB2  H N N 364 
TRP HB3  H N N 365 
TRP HD1  H N N 366 
TRP HE1  H N N 367 
TRP HE3  H N N 368 
TRP HZ2  H N N 369 
TRP HZ3  H N N 370 
TRP HH2  H N N 371 
TRP HXT  H N N 372 
TYR N    N N N 373 
TYR CA   C N S 374 
TYR C    C N N 375 
TYR O    O N N 376 
TYR CB   C N N 377 
TYR CG   C Y N 378 
TYR CD1  C Y N 379 
TYR CD2  C Y N 380 
TYR CE1  C Y N 381 
TYR CE2  C Y N 382 
TYR CZ   C Y N 383 
TYR OH   O N N 384 
TYR OXT  O N N 385 
TYR H    H N N 386 
TYR H2   H N N 387 
TYR HA   H N N 388 
TYR HB2  H N N 389 
TYR HB3  H N N 390 
TYR HD1  H N N 391 
TYR HD2  H N N 392 
TYR HE1  H N N 393 
TYR HE2  H N N 394 
TYR HH   H N N 395 
TYR HXT  H N N 396 
VAL N    N N N 397 
VAL CA   C N S 398 
VAL C    C N N 399 
VAL O    O N N 400 
VAL CB   C N N 401 
VAL CG1  C N N 402 
VAL CG2  C N N 403 
VAL OXT  O N N 404 
VAL H    H N N 405 
VAL H2   H N N 406 
VAL HA   H N N 407 
VAL HB   H N N 408 
VAL HG11 H N N 409 
VAL HG12 H N N 410 
VAL HG13 H N N 411 
VAL HG21 H N N 412 
VAL HG22 H N N 413 
VAL HG23 H N N 414 
VAL HXT  H N N 415 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CW3 O13 N11  sing N N 70  
CW3 N04 C03  sing N N 71  
CW3 N04 C05  sing N N 72  
CW3 C03 C02  sing N N 73  
CW3 N11 O12  doub N N 74  
CW3 N11 C10  sing N N 75  
CW3 C05 C10  doub Y N 76  
CW3 C05 C06  sing Y N 77  
CW3 C02 C01  sing N N 78  
CW3 C10 C09  sing Y N 79  
CW3 C06 C07  doub Y N 80  
CW3 C09 C08  doub Y N 81  
CW3 C07 C08  sing Y N 82  
CW3 C08 C14  sing N N 83  
CW3 C14 O15  doub N N 84  
CW3 C14 O16  sing N N 85  
CW3 C01 H1   sing N N 86  
CW3 C01 H2   sing N N 87  
CW3 C01 H3   sing N N 88  
CW3 C02 H4   sing N N 89  
CW3 C02 H5   sing N N 90  
CW3 C03 H6   sing N N 91  
CW3 C03 H7   sing N N 92  
CW3 N04 H8   sing N N 93  
CW3 C06 H9   sing N N 94  
CW3 C07 H10  sing N N 95  
CW3 C09 H11  sing N N 96  
CW3 O16 H12  sing N N 97  
CYS N   CA   sing N N 98  
CYS N   H    sing N N 99  
CYS N   H2   sing N N 100 
CYS CA  C    sing N N 101 
CYS CA  CB   sing N N 102 
CYS CA  HA   sing N N 103 
CYS C   O    doub N N 104 
CYS C   OXT  sing N N 105 
CYS CB  SG   sing N N 106 
CYS CB  HB2  sing N N 107 
CYS CB  HB3  sing N N 108 
CYS SG  HG   sing N N 109 
CYS OXT HXT  sing N N 110 
GLN N   CA   sing N N 111 
GLN N   H    sing N N 112 
GLN N   H2   sing N N 113 
GLN CA  C    sing N N 114 
GLN CA  CB   sing N N 115 
GLN CA  HA   sing N N 116 
GLN C   O    doub N N 117 
GLN C   OXT  sing N N 118 
GLN CB  CG   sing N N 119 
GLN CB  HB2  sing N N 120 
GLN CB  HB3  sing N N 121 
GLN CG  CD   sing N N 122 
GLN CG  HG2  sing N N 123 
GLN CG  HG3  sing N N 124 
GLN CD  OE1  doub N N 125 
GLN CD  NE2  sing N N 126 
GLN NE2 HE21 sing N N 127 
GLN NE2 HE22 sing N N 128 
GLN OXT HXT  sing N N 129 
GLU N   CA   sing N N 130 
GLU N   H    sing N N 131 
GLU N   H2   sing N N 132 
GLU CA  C    sing N N 133 
GLU CA  CB   sing N N 134 
GLU CA  HA   sing N N 135 
GLU C   O    doub N N 136 
GLU C   OXT  sing N N 137 
GLU CB  CG   sing N N 138 
GLU CB  HB2  sing N N 139 
GLU CB  HB3  sing N N 140 
GLU CG  CD   sing N N 141 
GLU CG  HG2  sing N N 142 
GLU CG  HG3  sing N N 143 
GLU CD  OE1  doub N N 144 
GLU CD  OE2  sing N N 145 
GLU OE2 HE2  sing N N 146 
GLU OXT HXT  sing N N 147 
GLY N   CA   sing N N 148 
GLY N   H    sing N N 149 
GLY N   H2   sing N N 150 
GLY CA  C    sing N N 151 
GLY CA  HA2  sing N N 152 
GLY CA  HA3  sing N N 153 
GLY C   O    doub N N 154 
GLY C   OXT  sing N N 155 
GLY OXT HXT  sing N N 156 
HIS N   CA   sing N N 157 
HIS N   H    sing N N 158 
HIS N   H2   sing N N 159 
HIS CA  C    sing N N 160 
HIS CA  CB   sing N N 161 
HIS CA  HA   sing N N 162 
HIS C   O    doub N N 163 
HIS C   OXT  sing N N 164 
HIS CB  CG   sing N N 165 
HIS CB  HB2  sing N N 166 
HIS CB  HB3  sing N N 167 
HIS CG  ND1  sing Y N 168 
HIS CG  CD2  doub Y N 169 
HIS ND1 CE1  doub Y N 170 
HIS ND1 HD1  sing N N 171 
HIS CD2 NE2  sing Y N 172 
HIS CD2 HD2  sing N N 173 
HIS CE1 NE2  sing Y N 174 
HIS CE1 HE1  sing N N 175 
HIS NE2 HE2  sing N N 176 
HIS OXT HXT  sing N N 177 
ILE N   CA   sing N N 178 
ILE N   H    sing N N 179 
ILE N   H2   sing N N 180 
ILE CA  C    sing N N 181 
ILE CA  CB   sing N N 182 
ILE CA  HA   sing N N 183 
ILE C   O    doub N N 184 
ILE C   OXT  sing N N 185 
ILE CB  CG1  sing N N 186 
ILE CB  CG2  sing N N 187 
ILE CB  HB   sing N N 188 
ILE CG1 CD1  sing N N 189 
ILE CG1 HG12 sing N N 190 
ILE CG1 HG13 sing N N 191 
ILE CG2 HG21 sing N N 192 
ILE CG2 HG22 sing N N 193 
ILE CG2 HG23 sing N N 194 
ILE CD1 HD11 sing N N 195 
ILE CD1 HD12 sing N N 196 
ILE CD1 HD13 sing N N 197 
ILE OXT HXT  sing N N 198 
LEU N   CA   sing N N 199 
LEU N   H    sing N N 200 
LEU N   H2   sing N N 201 
LEU CA  C    sing N N 202 
LEU CA  CB   sing N N 203 
LEU CA  HA   sing N N 204 
LEU C   O    doub N N 205 
LEU C   OXT  sing N N 206 
LEU CB  CG   sing N N 207 
LEU CB  HB2  sing N N 208 
LEU CB  HB3  sing N N 209 
LEU CG  CD1  sing N N 210 
LEU CG  CD2  sing N N 211 
LEU CG  HG   sing N N 212 
LEU CD1 HD11 sing N N 213 
LEU CD1 HD12 sing N N 214 
LEU CD1 HD13 sing N N 215 
LEU CD2 HD21 sing N N 216 
LEU CD2 HD22 sing N N 217 
LEU CD2 HD23 sing N N 218 
LEU OXT HXT  sing N N 219 
LYS N   CA   sing N N 220 
LYS N   H    sing N N 221 
LYS N   H2   sing N N 222 
LYS CA  C    sing N N 223 
LYS CA  CB   sing N N 224 
LYS CA  HA   sing N N 225 
LYS C   O    doub N N 226 
LYS C   OXT  sing N N 227 
LYS CB  CG   sing N N 228 
LYS CB  HB2  sing N N 229 
LYS CB  HB3  sing N N 230 
LYS CG  CD   sing N N 231 
LYS CG  HG2  sing N N 232 
LYS CG  HG3  sing N N 233 
LYS CD  CE   sing N N 234 
LYS CD  HD2  sing N N 235 
LYS CD  HD3  sing N N 236 
LYS CE  NZ   sing N N 237 
LYS CE  HE2  sing N N 238 
LYS CE  HE3  sing N N 239 
LYS NZ  HZ1  sing N N 240 
LYS NZ  HZ2  sing N N 241 
LYS NZ  HZ3  sing N N 242 
LYS OXT HXT  sing N N 243 
MET N   CA   sing N N 244 
MET N   H    sing N N 245 
MET N   H2   sing N N 246 
MET CA  C    sing N N 247 
MET CA  CB   sing N N 248 
MET CA  HA   sing N N 249 
MET C   O    doub N N 250 
MET C   OXT  sing N N 251 
MET CB  CG   sing N N 252 
MET CB  HB2  sing N N 253 
MET CB  HB3  sing N N 254 
MET CG  SD   sing N N 255 
MET CG  HG2  sing N N 256 
MET CG  HG3  sing N N 257 
MET SD  CE   sing N N 258 
MET CE  HE1  sing N N 259 
MET CE  HE2  sing N N 260 
MET CE  HE3  sing N N 261 
MET OXT HXT  sing N N 262 
PHE N   CA   sing N N 263 
PHE N   H    sing N N 264 
PHE N   H2   sing N N 265 
PHE CA  C    sing N N 266 
PHE CA  CB   sing N N 267 
PHE CA  HA   sing N N 268 
PHE C   O    doub N N 269 
PHE C   OXT  sing N N 270 
PHE CB  CG   sing N N 271 
PHE CB  HB2  sing N N 272 
PHE CB  HB3  sing N N 273 
PHE CG  CD1  doub Y N 274 
PHE CG  CD2  sing Y N 275 
PHE CD1 CE1  sing Y N 276 
PHE CD1 HD1  sing N N 277 
PHE CD2 CE2  doub Y N 278 
PHE CD2 HD2  sing N N 279 
PHE CE1 CZ   doub Y N 280 
PHE CE1 HE1  sing N N 281 
PHE CE2 CZ   sing Y N 282 
PHE CE2 HE2  sing N N 283 
PHE CZ  HZ   sing N N 284 
PHE OXT HXT  sing N N 285 
PRO N   CA   sing N N 286 
PRO N   CD   sing N N 287 
PRO N   H    sing N N 288 
PRO CA  C    sing N N 289 
PRO CA  CB   sing N N 290 
PRO CA  HA   sing N N 291 
PRO C   O    doub N N 292 
PRO C   OXT  sing N N 293 
PRO CB  CG   sing N N 294 
PRO CB  HB2  sing N N 295 
PRO CB  HB3  sing N N 296 
PRO CG  CD   sing N N 297 
PRO CG  HG2  sing N N 298 
PRO CG  HG3  sing N N 299 
PRO CD  HD2  sing N N 300 
PRO CD  HD3  sing N N 301 
PRO OXT HXT  sing N N 302 
SER N   CA   sing N N 303 
SER N   H    sing N N 304 
SER N   H2   sing N N 305 
SER CA  C    sing N N 306 
SER CA  CB   sing N N 307 
SER CA  HA   sing N N 308 
SER C   O    doub N N 309 
SER C   OXT  sing N N 310 
SER CB  OG   sing N N 311 
SER CB  HB2  sing N N 312 
SER CB  HB3  sing N N 313 
SER OG  HG   sing N N 314 
SER OXT HXT  sing N N 315 
THR N   CA   sing N N 316 
THR N   H    sing N N 317 
THR N   H2   sing N N 318 
THR CA  C    sing N N 319 
THR CA  CB   sing N N 320 
THR CA  HA   sing N N 321 
THR C   O    doub N N 322 
THR C   OXT  sing N N 323 
THR CB  OG1  sing N N 324 
THR CB  CG2  sing N N 325 
THR CB  HB   sing N N 326 
THR OG1 HG1  sing N N 327 
THR CG2 HG21 sing N N 328 
THR CG2 HG22 sing N N 329 
THR CG2 HG23 sing N N 330 
THR OXT HXT  sing N N 331 
TRP N   CA   sing N N 332 
TRP N   H    sing N N 333 
TRP N   H2   sing N N 334 
TRP CA  C    sing N N 335 
TRP CA  CB   sing N N 336 
TRP CA  HA   sing N N 337 
TRP C   O    doub N N 338 
TRP C   OXT  sing N N 339 
TRP CB  CG   sing N N 340 
TRP CB  HB2  sing N N 341 
TRP CB  HB3  sing N N 342 
TRP CG  CD1  doub Y N 343 
TRP CG  CD2  sing Y N 344 
TRP CD1 NE1  sing Y N 345 
TRP CD1 HD1  sing N N 346 
TRP CD2 CE2  doub Y N 347 
TRP CD2 CE3  sing Y N 348 
TRP NE1 CE2  sing Y N 349 
TRP NE1 HE1  sing N N 350 
TRP CE2 CZ2  sing Y N 351 
TRP CE3 CZ3  doub Y N 352 
TRP CE3 HE3  sing N N 353 
TRP CZ2 CH2  doub Y N 354 
TRP CZ2 HZ2  sing N N 355 
TRP CZ3 CH2  sing Y N 356 
TRP CZ3 HZ3  sing N N 357 
TRP CH2 HH2  sing N N 358 
TRP OXT HXT  sing N N 359 
TYR N   CA   sing N N 360 
TYR N   H    sing N N 361 
TYR N   H2   sing N N 362 
TYR CA  C    sing N N 363 
TYR CA  CB   sing N N 364 
TYR CA  HA   sing N N 365 
TYR C   O    doub N N 366 
TYR C   OXT  sing N N 367 
TYR CB  CG   sing N N 368 
TYR CB  HB2  sing N N 369 
TYR CB  HB3  sing N N 370 
TYR CG  CD1  doub Y N 371 
TYR CG  CD2  sing Y N 372 
TYR CD1 CE1  sing Y N 373 
TYR CD1 HD1  sing N N 374 
TYR CD2 CE2  doub Y N 375 
TYR CD2 HD2  sing N N 376 
TYR CE1 CZ   doub Y N 377 
TYR CE1 HE1  sing N N 378 
TYR CE2 CZ   sing Y N 379 
TYR CE2 HE2  sing N N 380 
TYR CZ  OH   sing N N 381 
TYR OH  HH   sing N N 382 
TYR OXT HXT  sing N N 383 
VAL N   CA   sing N N 384 
VAL N   H    sing N N 385 
VAL N   H2   sing N N 386 
VAL CA  C    sing N N 387 
VAL CA  CB   sing N N 388 
VAL CA  HA   sing N N 389 
VAL C   O    doub N N 390 
VAL C   OXT  sing N N 391 
VAL CB  CG1  sing N N 392 
VAL CB  CG2  sing N N 393 
VAL CB  HB   sing N N 394 
VAL CG1 HG11 sing N N 395 
VAL CG1 HG12 sing N N 396 
VAL CG1 HG13 sing N N 397 
VAL CG2 HG21 sing N N 398 
VAL CG2 HG22 sing N N 399 
VAL CG2 HG23 sing N N 400 
VAL OXT HXT  sing N N 401 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-05-15 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8JEI 
_em_admin.last_update        2024-11-20 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'Cryo-EM Structure of the compuond 5c-HCAR3-Gi complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_embedding.details       ? 
_em_embedding.id            1 
_em_embedding.material      'vitreous ice' 
_em_embedding.specimen_id   1 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         3.19 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       YES 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8JEI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 1   ? 142.042 108.489 141.176 1.00 79.90  ?  4   THR C N   1 
ATOM   2    C CA  . THR A 1 1   ? 142.890 108.280 142.344 1.00 79.90  ?  4   THR C CA  1 
ATOM   3    C C   . THR A 1 1   ? 142.189 108.731 143.621 1.00 79.90  ?  4   THR C C   1 
ATOM   4    O O   . THR A 1 1   ? 142.663 108.470 144.726 1.00 79.90  ?  4   THR C O   1 
ATOM   5    C CB  . THR A 1 1   ? 144.226 109.032 142.213 1.00 79.90  ?  4   THR C CB  1 
ATOM   6    O OG1 . THR A 1 1   ? 144.998 108.850 143.407 1.00 79.90  ?  4   THR C OG1 1 
ATOM   7    C CG2 . THR A 1 1   ? 143.982 110.517 141.994 1.00 79.90  ?  4   THR C CG2 1 
ATOM   8    N N   . LEU A 1 2   ? 141.058 109.413 143.460 1.00 72.33  ?  5   LEU C N   1 
ATOM   9    C CA  . LEU A 1 2   ? 140.302 109.896 144.603 1.00 72.33  ?  5   LEU C CA  1 
ATOM   10   C C   . LEU A 1 2   ? 139.585 108.743 145.302 1.00 72.33  ?  5   LEU C C   1 
ATOM   11   O O   . LEU A 1 2   ? 139.314 107.693 144.714 1.00 72.33  ?  5   LEU C O   1 
ATOM   12   C CB  . LEU A 1 2   ? 139.284 110.949 144.167 1.00 72.33  ?  5   LEU C CB  1 
ATOM   13   C CG  . LEU A 1 2   ? 139.795 112.080 143.274 1.00 72.33  ?  5   LEU C CG  1 
ATOM   14   C CD1 . LEU A 1 2   ? 138.651 112.992 142.866 1.00 72.33  ?  5   LEU C CD1 1 
ATOM   15   C CD2 . LEU A 1 2   ? 140.890 112.867 143.972 1.00 72.33  ?  5   LEU C CD2 1 
ATOM   16   N N   . SER A 1 3   ? 139.281 108.952 146.580 1.00 68.44  ?  6   SER C N   1 
ATOM   17   C CA  . SER A 1 3   ? 138.502 107.990 147.340 1.00 68.44  ?  6   SER C CA  1 
ATOM   18   C C   . SER A 1 3   ? 137.015 108.184 147.054 1.00 68.44  ?  6   SER C C   1 
ATOM   19   O O   . SER A 1 3   ? 136.609 109.081 146.310 1.00 68.44  ?  6   SER C O   1 
ATOM   20   C CB  . SER A 1 3   ? 138.803 108.121 148.831 1.00 68.44  ?  6   SER C CB  1 
ATOM   21   O OG  . SER A 1 3   ? 138.593 109.448 149.280 1.00 68.44  ?  6   SER C OG  1 
ATOM   22   N N   . ALA A 1 4   ? 136.186 107.323 147.647 1.00 66.70  ?  7   ALA C N   1 
ATOM   23   C CA  . ALA A 1 4   ? 134.744 107.423 147.439 1.00 66.70  ?  7   ALA C CA  1 
ATOM   24   C C   . ALA A 1 4   ? 134.195 108.720 148.019 1.00 66.70  ?  7   ALA C C   1 
ATOM   25   O O   . ALA A 1 4   ? 133.411 109.424 147.371 1.00 66.70  ?  7   ALA C O   1 
ATOM   26   C CB  . ALA A 1 4   ? 134.042 106.214 148.056 1.00 66.70  ?  7   ALA C CB  1 
ATOM   27   N N   . GLU A 1 5   ? 134.602 109.054 149.246 1.00 64.17  ?  8   GLU C N   1 
ATOM   28   C CA  . GLU A 1 5   ? 134.138 110.288 149.869 1.00 64.17  ?  8   GLU C CA  1 
ATOM   29   C C   . GLU A 1 5   ? 134.630 111.510 149.107 1.00 64.17  ?  8   GLU C C   1 
ATOM   30   O O   . GLU A 1 5   ? 133.886 112.481 148.931 1.00 64.17  ?  8   GLU C O   1 
ATOM   31   C CB  . GLU A 1 5   ? 134.596 110.344 151.324 1.00 64.17  ?  8   GLU C CB  1 
ATOM   32   C CG  . GLU A 1 5   ? 134.158 109.154 152.152 1.00 64.17  ?  8   GLU C CG  1 
ATOM   33   C CD  . GLU A 1 5   ? 134.012 109.496 153.617 1.00 64.17  ?  8   GLU C CD  1 
ATOM   34   O OE1 . GLU A 1 5   ? 133.986 110.699 153.948 1.00 64.17  ?  8   GLU C OE1 1 
ATOM   35   O OE2 . GLU A 1 5   ? 133.923 108.562 154.440 1.00 64.17  -1 8   GLU C OE2 1 
ATOM   36   N N   . ASP A 1 6   ? 135.881 111.482 148.647 1.00 67.78  ?  9   ASP C N   1 
ATOM   37   C CA  . ASP A 1 6   ? 136.412 112.611 147.891 1.00 67.78  ?  9   ASP C CA  1 
ATOM   38   C C   . ASP A 1 6   ? 135.694 112.752 146.552 1.00 67.78  ?  9   ASP C C   1 
ATOM   39   O O   . ASP A 1 6   ? 135.401 113.870 146.112 1.00 67.78  ?  9   ASP C O   1 
ATOM   40   C CB  . ASP A 1 6   ? 137.920 112.439 147.697 1.00 67.78  ?  9   ASP C CB  1 
ATOM   41   C CG  . ASP A 1 6   ? 138.590 113.671 147.108 1.00 67.78  ?  9   ASP C CG  1 
ATOM   42   O OD1 . ASP A 1 6   ? 137.898 114.667 146.812 1.00 67.78  ?  9   ASP C OD1 1 
ATOM   43   O OD2 . ASP A 1 6   ? 139.828 113.644 146.949 1.00 67.78  -1 9   ASP C OD2 1 
ATOM   44   N N   . LYS A 1 7   ? 135.388 111.630 145.897 1.00 64.56  ?  10  LYS C N   1 
ATOM   45   C CA  . LYS A 1 7   ? 134.636 111.684 144.647 1.00 64.56  ?  10  LYS C CA  1 
ATOM   46   C C   . LYS A 1 7   ? 133.238 112.249 144.866 1.00 64.56  ?  10  LYS C C   1 
ATOM   47   O O   . LYS A 1 7   ? 132.748 113.049 144.059 1.00 64.56  ?  10  LYS C O   1 
ATOM   48   C CB  . LYS A 1 7   ? 134.562 110.293 144.018 1.00 64.56  ?  10  LYS C CB  1 
ATOM   49   C CG  . LYS A 1 7   ? 135.748 109.952 143.133 1.00 64.56  ?  10  LYS C CG  1 
ATOM   50   C CD  . LYS A 1 7   ? 135.564 108.604 142.460 1.00 64.56  ?  10  LYS C CD  1 
ATOM   51   C CE  . LYS A 1 7   ? 136.017 107.474 143.367 1.00 64.56  ?  10  LYS C CE  1 
ATOM   52   N NZ  . LYS A 1 7   ? 136.122 106.183 142.636 1.00 64.56  1  10  LYS C NZ  1 
ATOM   53   N N   . ALA A 1 8   ? 132.578 111.846 145.954 1.00 59.95  ?  11  ALA C N   1 
ATOM   54   C CA  . ALA A 1 8   ? 131.254 112.386 146.248 1.00 59.95  ?  11  ALA C CA  1 
ATOM   55   C C   . ALA A 1 8   ? 131.322 113.873 146.580 1.00 59.95  ?  11  ALA C C   1 
ATOM   56   O O   . ALA A 1 8   ? 130.421 114.639 146.217 1.00 59.95  ?  11  ALA C O   1 
ATOM   57   C CB  . ALA A 1 8   ? 130.612 111.601 147.389 1.00 59.95  ?  11  ALA C CB  1 
ATOM   58   N N   . ALA A 1 9   ? 132.382 114.300 147.270 1.00 58.45  ?  12  ALA C N   1 
ATOM   59   C CA  . ALA A 1 9   ? 132.574 115.723 147.528 1.00 58.45  ?  12  ALA C CA  1 
ATOM   60   C C   . ALA A 1 9   ? 132.772 116.494 146.230 1.00 58.45  ?  12  ALA C C   1 
ATOM   61   O O   . ALA A 1 9   ? 132.259 117.608 146.075 1.00 58.45  ?  12  ALA C O   1 
ATOM   62   C CB  . ALA A 1 9   ? 133.763 115.933 148.464 1.00 58.45  ?  12  ALA C CB  1 
ATOM   63   N N   . VAL A 1 10  ? 133.522 115.919 145.289 1.00 59.10  ?  13  VAL C N   1 
ATOM   64   C CA  . VAL A 1 10  ? 133.703 116.551 143.984 1.00 59.10  ?  13  VAL C CA  1 
ATOM   65   C C   . VAL A 1 10  ? 132.370 116.655 143.255 1.00 59.10  ?  13  VAL C C   1 
ATOM   66   O O   . VAL A 1 10  ? 132.076 117.666 142.605 1.00 59.10  ?  13  VAL C O   1 
ATOM   67   C CB  . VAL A 1 10  ? 134.746 115.776 143.157 1.00 59.10  ?  13  VAL C CB  1 
ATOM   68   C CG1 . VAL A 1 10  ? 134.717 116.221 141.706 1.00 59.10  ?  13  VAL C CG1 1 
ATOM   69   C CG2 . VAL A 1 10  ? 136.134 115.968 143.744 1.00 59.10  ?  13  VAL C CG2 1 
ATOM   70   N N   . GLU A 1 11  ? 131.544 115.611 143.344 1.00 61.79  ?  14  GLU C N   1 
ATOM   71   C CA  . GLU A 1 11  ? 130.222 115.658 142.725 1.00 61.79  ?  14  GLU C CA  1 
ATOM   72   C C   . GLU A 1 11  ? 129.358 116.752 143.343 1.00 61.79  ?  14  GLU C C   1 
ATOM   73   O O   . GLU A 1 11  ? 128.646 117.473 142.630 1.00 61.79  ?  14  GLU C O   1 
ATOM   74   C CB  . GLU A 1 11  ? 129.537 114.298 142.850 1.00 61.79  ?  14  GLU C CB  1 
ATOM   75   C CG  . GLU A 1 11  ? 128.334 114.125 141.943 1.00 61.79  ?  14  GLU C CG  1 
ATOM   76   C CD  . GLU A 1 11  ? 127.441 112.981 142.375 1.00 61.79  ?  14  GLU C CD  1 
ATOM   77   O OE1 . GLU A 1 11  ? 127.976 111.942 142.815 1.00 61.79  ?  14  GLU C OE1 1 
ATOM   78   O OE2 . GLU A 1 11  ? 126.204 113.121 142.276 1.00 61.79  -1 14  GLU C OE2 1 
ATOM   79   N N   . ARG A 1 12  ? 129.401 116.885 144.670 1.00 55.84  ?  15  ARG C N   1 
ATOM   80   C CA  . ARG A 1 12  ? 128.655 117.951 145.332 1.00 55.84  ?  15  ARG C CA  1 
ATOM   81   C C   . ARG A 1 12  ? 129.157 119.323 144.899 1.00 55.84  ?  15  ARG C C   1 
ATOM   82   O O   . ARG A 1 12  ? 128.363 120.247 144.683 1.00 55.84  ?  15  ARG C O   1 
ATOM   83   C CB  . ARG A 1 12  ? 128.751 117.795 146.850 1.00 55.84  ?  15  ARG C CB  1 
ATOM   84   C CG  . ARG A 1 12  ? 128.583 119.093 147.620 1.00 55.84  ?  15  ARG C CG  1 
ATOM   85   C CD  . ARG A 1 12  ? 128.864 118.903 149.097 1.00 55.84  ?  15  ARG C CD  1 
ATOM   86   N NE  . ARG A 1 12  ? 128.476 120.071 149.877 1.00 55.84  ?  15  ARG C NE  1 
ATOM   87   C CZ  . ARG A 1 12  ? 127.266 120.264 150.384 1.00 55.84  ?  15  ARG C CZ  1 
ATOM   88   N NH1 . ARG A 1 12  ? 126.295 119.384 150.207 1.00 55.84  1  15  ARG C NH1 1 
ATOM   89   N NH2 . ARG A 1 12  ? 127.025 121.367 151.085 1.00 55.84  ?  15  ARG C NH2 1 
ATOM   90   N N   . SER A 1 13  ? 130.476 119.475 144.769 1.00 58.70  ?  16  SER C N   1 
ATOM   91   C CA  . SER A 1 13  ? 131.036 120.738 144.301 1.00 58.70  ?  16  SER C CA  1 
ATOM   92   C C   . SER A 1 13  ? 130.587 121.046 142.879 1.00 58.70  ?  16  SER C C   1 
ATOM   93   O O   . SER A 1 13  ? 130.320 122.203 142.542 1.00 58.70  ?  16  SER C O   1 
ATOM   94   C CB  . SER A 1 13  ? 132.560 120.700 144.387 1.00 58.70  ?  16  SER C CB  1 
ATOM   95   O OG  . SER A 1 13  ? 133.138 121.689 143.555 1.00 58.70  ?  16  SER C OG  1 
ATOM   96   N N   . LYS A 1 14  ? 130.509 120.023 142.026 1.00 62.86  ?  17  LYS C N   1 
ATOM   97   C CA  . LYS A 1 14  ? 130.032 120.232 140.661 1.00 62.86  ?  17  LYS C CA  1 
ATOM   98   C C   . LYS A 1 14  ? 128.562 120.638 140.643 1.00 62.86  ?  17  LYS C C   1 
ATOM   99   O O   . LYS A 1 14  ? 128.156 121.489 139.841 1.00 62.86  ?  17  LYS C O   1 
ATOM   100  C CB  . LYS A 1 14  ? 130.255 118.972 139.827 1.00 62.86  ?  17  LYS C CB  1 
ATOM   101  C CG  . LYS A 1 14  ? 131.714 118.700 139.502 1.00 62.86  ?  17  LYS C CG  1 
ATOM   102  C CD  . LYS A 1 14  ? 131.861 117.989 138.168 1.00 62.86  ?  17  LYS C CD  1 
ATOM   103  C CE  . LYS A 1 14  ? 131.153 116.645 138.177 1.00 62.86  ?  17  LYS C CE  1 
ATOM   104  N NZ  . LYS A 1 14  ? 132.037 115.554 138.674 1.00 62.86  1  17  LYS C NZ  1 
ATOM   105  N N   . MET A 1 15  ? 127.747 120.037 141.512 1.00 66.21  ?  18  MET C N   1 
ATOM   106  C CA  . MET A 1 15  ? 126.353 120.459 141.620 1.00 66.21  ?  18  MET C CA  1 
ATOM   107  C C   . MET A 1 15  ? 126.252 121.907 142.084 1.00 66.21  ?  18  MET C C   1 
ATOM   108  O O   . MET A 1 15  ? 125.426 122.679 141.578 1.00 66.21  ?  18  MET C O   1 
ATOM   109  C CB  . MET A 1 15  ? 125.594 119.537 142.573 1.00 66.21  ?  18  MET C CB  1 
ATOM   110  C CG  . MET A 1 15  ? 125.157 118.225 141.951 1.00 66.21  ?  18  MET C CG  1 
ATOM   111  S SD  . MET A 1 15  ? 123.726 117.518 142.786 1.00 66.21  ?  18  MET C SD  1 
ATOM   112  C CE  . MET A 1 15  ? 122.621 118.926 142.813 1.00 66.21  ?  18  MET C CE  1 
ATOM   113  N N   . ILE A 1 16  ? 127.086 122.291 143.053 1.00 62.48  ?  19  ILE C N   1 
ATOM   114  C CA  . ILE A 1 16  ? 127.117 123.676 143.514 1.00 62.48  ?  19  ILE C CA  1 
ATOM   115  C C   . ILE A 1 16  ? 127.522 124.604 142.375 1.00 62.48  ?  19  ILE C C   1 
ATOM   116  O O   . ILE A 1 16  ? 126.968 125.697 142.218 1.00 62.48  ?  19  ILE C O   1 
ATOM   117  C CB  . ILE A 1 16  ? 128.059 123.811 144.725 1.00 62.48  ?  19  ILE C CB  1 
ATOM   118  C CG1 . ILE A 1 16  ? 127.379 123.285 145.989 1.00 62.48  ?  19  ILE C CG1 1 
ATOM   119  C CG2 . ILE A 1 16  ? 128.489 125.252 144.920 1.00 62.48  ?  19  ILE C CG2 1 
ATOM   120  C CD1 . ILE A 1 16  ? 128.287 123.238 147.190 1.00 62.48  ?  19  ILE C CD1 1 
ATOM   121  N N   . ASP A 1 17  ? 128.494 124.180 141.565 1.00 66.69  ?  20  ASP C N   1 
ATOM   122  C CA  . ASP A 1 17  ? 128.896 124.959 140.398 1.00 66.69  ?  20  ASP C CA  1 
ATOM   123  C C   . ASP A 1 17  ? 127.739 125.135 139.427 1.00 66.69  ?  20  ASP C C   1 
ATOM   124  O O   . ASP A 1 17  ? 127.546 126.222 138.870 1.00 66.69  ?  20  ASP C O   1 
ATOM   125  C CB  . ASP A 1 17  ? 130.073 124.281 139.698 1.00 66.69  ?  20  ASP C CB  1 
ATOM   126  C CG  . ASP A 1 17  ? 131.410 124.789 140.182 1.00 66.69  ?  20  ASP C CG  1 
ATOM   127  O OD1 . ASP A 1 17  ? 131.511 125.995 140.479 1.00 66.69  ?  20  ASP C OD1 1 
ATOM   128  O OD2 . ASP A 1 17  ? 132.361 123.984 140.265 1.00 66.69  -1 20  ASP C OD2 1 
ATOM   129  N N   . ARG A 1 18  ? 126.971 124.070 139.195 1.00 72.64  ?  21  ARG C N   1 
ATOM   130  C CA  . ARG A 1 18  ? 125.824 124.167 138.298 1.00 72.64  ?  21  ARG C CA  1 
ATOM   131  C C   . ARG A 1 18  ? 124.788 125.150 138.832 1.00 72.64  ?  21  ARG C C   1 
ATOM   132  O O   . ARG A 1 18  ? 124.252 125.972 138.077 1.00 72.64  ?  21  ARG C O   1 
ATOM   133  C CB  . ARG A 1 18  ? 125.204 122.786 138.091 1.00 72.64  ?  21  ARG C CB  1 
ATOM   134  C CG  . ARG A 1 18  ? 123.724 122.809 137.749 1.00 72.64  ?  21  ARG C CG  1 
ATOM   135  C CD  . ARG A 1 18  ? 123.327 121.590 136.934 1.00 72.64  ?  21  ARG C CD  1 
ATOM   136  N NE  . ARG A 1 18  ? 123.232 120.389 137.756 1.00 72.64  ?  21  ARG C NE  1 
ATOM   137  C CZ  . ARG A 1 18  ? 124.144 119.428 137.785 1.00 72.64  ?  21  ARG C CZ  1 
ATOM   138  N NH1 . ARG A 1 18  ? 125.242 119.493 137.049 1.00 72.64  1  21  ARG C NH1 1 
ATOM   139  N NH2 . ARG A 1 18  ? 123.952 118.374 138.574 1.00 72.64  ?  21  ARG C NH2 1 
ATOM   140  N N   . ASN A 1 19  ? 124.500 125.085 140.134 1.00 72.63  ?  22  ASN C N   1 
ATOM   141  C CA  . ASN A 1 19  ? 123.548 126.027 140.720 1.00 72.63  ?  22  ASN C CA  1 
ATOM   142  C C   . ASN A 1 19  ? 124.055 127.462 140.627 1.00 72.63  ?  22  ASN C C   1 
ATOM   143  O O   . ASN A 1 19  ? 123.283 128.383 140.332 1.00 72.63  ?  22  ASN C O   1 
ATOM   144  C CB  . ASN A 1 19  ? 123.249 125.658 142.173 1.00 72.63  ?  22  ASN C CB  1 
ATOM   145  C CG  . ASN A 1 19  ? 122.568 124.311 142.305 1.00 72.63  ?  22  ASN C CG  1 
ATOM   146  O OD1 . ASN A 1 19  ? 123.128 123.371 142.866 1.00 72.63  ?  22  ASN C OD1 1 
ATOM   147  N ND2 . ASN A 1 19  ? 121.351 124.212 141.785 1.00 72.63  ?  22  ASN C ND2 1 
ATOM   148  N N   . LEU A 1 20  ? 125.349 127.673 140.879 1.00 68.97  ?  23  LEU C N   1 
ATOM   149  C CA  . LEU A 1 20  ? 125.917 129.013 140.774 1.00 68.97  ?  23  LEU C CA  1 
ATOM   150  C C   . LEU A 1 20  ? 125.834 129.536 139.347 1.00 68.97  ?  23  LEU C C   1 
ATOM   151  O O   . LEU A 1 20  ? 125.523 130.712 139.127 1.00 68.97  ?  23  LEU C O   1 
ATOM   152  C CB  . LEU A 1 20  ? 127.368 129.011 141.253 1.00 68.97  ?  23  LEU C CB  1 
ATOM   153  C CG  . LEU A 1 20  ? 127.614 128.763 142.739 1.00 68.97  ?  23  LEU C CG  1 
ATOM   154  C CD1 . LEU A 1 20  ? 129.098 128.650 143.008 1.00 68.97  ?  23  LEU C CD1 1 
ATOM   155  C CD2 . LEU A 1 20  ? 127.003 129.868 143.573 1.00 68.97  ?  23  LEU C CD2 1 
ATOM   156  N N   . ARG A 1 21  ? 126.124 128.681 138.365 1.00 74.56  ?  24  ARG C N   1 
ATOM   157  C CA  . ARG A 1 21  ? 126.034 129.095 136.969 1.00 74.56  ?  24  ARG C CA  1 
ATOM   158  C C   . ARG A 1 21  ? 124.603 129.452 136.593 1.00 74.56  ?  24  ARG C C   1 
ATOM   159  O O   . ARG A 1 21  ? 124.367 130.446 135.896 1.00 74.56  ?  24  ARG C O   1 
ATOM   160  C CB  . ARG A 1 21  ? 126.573 127.990 136.062 1.00 74.56  ?  24  ARG C CB  1 
ATOM   161  C CG  . ARG A 1 21  ? 126.271 128.188 134.588 1.00 74.56  ?  24  ARG C CG  1 
ATOM   162  C CD  . ARG A 1 21  ? 126.665 126.965 133.777 1.00 74.56  ?  24  ARG C CD  1 
ATOM   163  N NE  . ARG A 1 21  ? 127.723 126.198 134.423 1.00 74.56  ?  24  ARG C NE  1 
ATOM   164  C CZ  . ARG A 1 21  ? 127.636 124.911 134.727 1.00 74.56  ?  24  ARG C CZ  1 
ATOM   165  N NH1 . ARG A 1 21  ? 126.546 124.210 134.460 1.00 74.56  1  24  ARG C NH1 1 
ATOM   166  N NH2 . ARG A 1 21  ? 128.667 124.312 135.315 1.00 74.56  ?  24  ARG C NH2 1 
ATOM   167  N N   . GLU A 1 22  ? 123.632 128.654 137.045 1.00 78.18  ?  25  GLU C N   1 
ATOM   168  C CA  . GLU A 1 22  ? 122.234 128.968 136.763 1.00 78.18  ?  25  GLU C CA  1 
ATOM   169  C C   . GLU A 1 22  ? 121.825 130.290 137.402 1.00 78.18  ?  25  GLU C C   1 
ATOM   170  O O   . GLU A 1 22  ? 121.138 131.106 136.775 1.00 78.18  ?  25  GLU C O   1 
ATOM   171  C CB  . GLU A 1 22  ? 121.333 127.834 137.249 1.00 78.18  ?  25  GLU C CB  1 
ATOM   172  C CG  . GLU A 1 22  ? 121.393 126.586 136.387 1.00 78.18  ?  25  GLU C CG  1 
ATOM   173  C CD  . GLU A 1 22  ? 120.480 125.487 136.891 1.00 78.18  ?  25  GLU C CD  1 
ATOM   174  O OE1 . GLU A 1 22  ? 119.871 125.665 137.966 1.00 78.18  ?  25  GLU C OE1 1 
ATOM   175  O OE2 . GLU A 1 22  ? 120.372 124.444 136.212 1.00 78.18  -1 25  GLU C OE2 1 
ATOM   176  N N   . ASP A 1 23  ? 122.242 130.521 138.650 1.00 77.54  ?  26  ASP C N   1 
ATOM   177  C CA  . ASP A 1 23  ? 121.910 131.774 139.320 1.00 77.54  ?  26  ASP C CA  1 
ATOM   178  C C   . ASP A 1 23  ? 122.547 132.964 138.615 1.00 77.54  ?  26  ASP C C   1 
ATOM   179  O O   . ASP A 1 23  ? 121.919 134.018 138.469 1.00 77.54  ?  26  ASP C O   1 
ATOM   180  C CB  . ASP A 1 23  ? 122.349 131.718 140.783 1.00 77.54  ?  26  ASP C CB  1 
ATOM   181  C CG  . ASP A 1 23  ? 121.334 131.023 141.668 1.00 77.54  ?  26  ASP C CG  1 
ATOM   182  O OD1 . ASP A 1 23  ? 120.124 131.121 141.375 1.00 77.54  ?  26  ASP C OD1 1 
ATOM   183  O OD2 . ASP A 1 23  ? 121.746 130.379 142.655 1.00 77.54  -1 26  ASP C OD2 1 
ATOM   184  N N   . GLY A 1 24  ? 123.796 132.815 138.170 1.00 76.70  ?  27  GLY C N   1 
ATOM   185  C CA  . GLY A 1 24  ? 124.447 133.895 137.449 1.00 76.70  ?  27  GLY C CA  1 
ATOM   186  C C   . GLY A 1 24  ? 123.798 134.178 136.109 1.00 76.70  ?  27  GLY C C   1 
ATOM   187  O O   . GLY A 1 24  ? 123.683 135.335 135.699 1.00 76.70  ?  27  GLY C O   1 
ATOM   188  N N   . GLU A 1 25  ? 123.372 133.126 135.405 1.00 79.80  ?  28  GLU C N   1 
ATOM   189  C CA  . GLU A 1 25  ? 122.647 133.321 134.154 1.00 79.80  ?  28  GLU C CA  1 
ATOM   190  C C   . GLU A 1 25  ? 121.328 134.041 134.394 1.00 79.80  ?  28  GLU C C   1 
ATOM   191  O O   . GLU A 1 25  ? 120.938 134.917 133.613 1.00 79.80  ?  28  GLU C O   1 
ATOM   192  C CB  . GLU A 1 25  ? 122.409 131.977 133.469 1.00 79.80  ?  28  GLU C CB  1 
ATOM   193  C CG  . GLU A 1 25  ? 123.627 131.420 132.754 1.00 79.80  ?  28  GLU C CG  1 
ATOM   194  C CD  . GLU A 1 25  ? 123.421 129.996 132.279 1.00 79.80  ?  28  GLU C CD  1 
ATOM   195  O OE1 . GLU A 1 25  ? 122.300 129.470 132.444 1.00 79.80  ?  28  GLU C OE1 1 
ATOM   196  O OE2 . GLU A 1 25  ? 124.379 129.402 131.742 1.00 79.80  -1 28  GLU C OE2 1 
ATOM   197  N N   . LYS A 1 26  ? 120.621 133.678 135.467 1.00 80.48  ?  29  LYS C N   1 
ATOM   198  C CA  . LYS A 1 26  ? 119.379 134.370 135.800 1.00 80.48  ?  29  LYS C CA  1 
ATOM   199  C C   . LYS A 1 26  ? 119.632 135.834 136.137 1.00 80.48  ?  29  LYS C C   1 
ATOM   200  O O   . LYS A 1 26  ? 118.864 136.715 135.733 1.00 80.48  ?  29  LYS C O   1 
ATOM   201  C CB  . LYS A 1 26  ? 118.683 133.667 136.964 1.00 80.48  ?  29  LYS C CB  1 
ATOM   202  C CG  . LYS A 1 26  ? 117.312 134.228 137.294 1.00 80.48  ?  29  LYS C CG  1 
ATOM   203  C CD  . LYS A 1 26  ? 116.676 133.480 138.453 1.00 80.48  ?  29  LYS C CD  1 
ATOM   204  C CE  . LYS A 1 26  ? 116.259 132.078 138.042 1.00 80.48  ?  29  LYS C CE  1 
ATOM   205  N NZ  . LYS A 1 26  ? 115.148 132.096 137.051 1.00 80.48  1  29  LYS C NZ  1 
ATOM   206  N N   . ALA A 1 27  ? 120.704 136.114 136.882 1.00 79.80  ?  30  ALA C N   1 
ATOM   207  C CA  . ALA A 1 27  ? 120.986 137.486 137.292 1.00 79.80  ?  30  ALA C CA  1 
ATOM   208  C C   . ALA A 1 27  ? 121.439 138.342 136.116 1.00 79.80  ?  30  ALA C C   1 
ATOM   209  O O   . ALA A 1 27  ? 121.129 139.537 136.057 1.00 79.80  ?  30  ALA C O   1 
ATOM   210  C CB  . ALA A 1 27  ? 122.039 137.496 138.399 1.00 79.80  ?  30  ALA C CB  1 
ATOM   211  N N   . ALA A 1 28  ? 122.180 137.753 135.174 1.00 81.31  ?  31  ALA C N   1 
ATOM   212  C CA  . ALA A 1 28  ? 122.688 138.514 134.038 1.00 81.31  ?  31  ALA C CA  1 
ATOM   213  C C   . ALA A 1 28  ? 121.579 138.988 133.110 1.00 81.31  ?  31  ALA C C   1 
ATOM   214  O O   . ALA A 1 28  ? 121.788 139.945 132.356 1.00 81.31  ?  31  ALA C O   1 
ATOM   215  C CB  . ALA A 1 28  ? 123.698 137.677 133.253 1.00 81.31  ?  31  ALA C CB  1 
ATOM   216  N N   . ARG A 1 29  ? 120.412 138.349 133.144 1.00 83.62  ?  32  ARG C N   1 
ATOM   217  C CA  . ARG A 1 29  ? 119.289 138.755 132.311 1.00 83.62  ?  32  ARG C CA  1 
ATOM   218  C C   . ARG A 1 29  ? 118.474 139.882 132.927 1.00 83.62  ?  32  ARG C C   1 
ATOM   219  O O   . ARG A 1 29  ? 117.528 140.359 132.292 1.00 83.62  ?  32  ARG C O   1 
ATOM   220  C CB  . ARG A 1 29  ? 118.375 137.558 132.038 1.00 83.62  ?  32  ARG C CB  1 
ATOM   221  C CG  . ARG A 1 29  ? 119.004 136.470 131.189 1.00 83.62  ?  32  ARG C CG  1 
ATOM   222  C CD  . ARG A 1 29  ? 118.038 135.315 130.990 1.00 83.62  ?  32  ARG C CD  1 
ATOM   223  N NE  . ARG A 1 29  ? 117.779 134.604 132.236 1.00 83.62  ?  32  ARG C NE  1 
ATOM   224  C CZ  . ARG A 1 29  ? 116.875 133.644 132.377 1.00 83.62  ?  32  ARG C CZ  1 
ATOM   225  N NH1 . ARG A 1 29  ? 116.119 133.253 131.364 1.00 83.62  1  32  ARG C NH1 1 
ATOM   226  N NH2 . ARG A 1 29  ? 116.726 133.063 133.563 1.00 83.62  ?  32  ARG C NH2 1 
ATOM   227  N N   . GLU A 1 30  ? 118.812 140.316 134.136 1.00 80.14  ?  33  GLU C N   1 
ATOM   228  C CA  . GLU A 1 30  ? 118.067 141.350 134.834 1.00 80.14  ?  33  GLU C CA  1 
ATOM   229  C C   . GLU A 1 30  ? 118.778 142.691 134.718 1.00 80.14  ?  33  GLU C C   1 
ATOM   230  O O   . GLU A 1 30  ? 120.009 142.766 134.687 1.00 80.14  ?  33  GLU C O   1 
ATOM   231  C CB  . GLU A 1 30  ? 117.880 140.983 136.307 1.00 80.14  ?  33  GLU C CB  1 
ATOM   232  C CG  . GLU A 1 30  ? 117.055 139.726 136.524 1.00 80.14  ?  33  GLU C CG  1 
ATOM   233  C CD  . GLU A 1 30  ? 116.916 139.364 137.987 1.00 80.14  ?  33  GLU C CD  1 
ATOM   234  O OE1 . GLU A 1 30  ? 117.471 140.092 138.835 1.00 80.14  ?  33  GLU C OE1 1 
ATOM   235  O OE2 . GLU A 1 30  ? 116.252 138.351 138.290 1.00 80.14  -1 33  GLU C OE2 1 
ATOM   236  N N   . VAL A 1 31  ? 117.984 143.752 134.653 1.00 70.44  ?  34  VAL C N   1 
ATOM   237  C CA  . VAL A 1 31  ? 118.495 145.111 134.533 1.00 70.44  ?  34  VAL C CA  1 
ATOM   238  C C   . VAL A 1 31  ? 118.676 145.687 135.929 1.00 70.44  ?  34  VAL C C   1 
ATOM   239  O O   . VAL A 1 31  ? 117.787 145.566 136.779 1.00 70.44  ?  34  VAL C O   1 
ATOM   240  C CB  . VAL A 1 31  ? 117.545 145.980 133.694 1.00 70.44  ?  34  VAL C CB  1 
ATOM   241  C CG1 . VAL A 1 31  ? 118.017 147.420 133.677 1.00 70.44  ?  34  VAL C CG1 1 
ATOM   242  C CG2 . VAL A 1 31  ? 117.434 145.427 132.285 1.00 70.44  ?  34  VAL C CG2 1 
ATOM   243  N N   . LYS A 1 32  ? 119.834 146.289 136.176 1.00 65.17  ?  35  LYS C N   1 
ATOM   244  C CA  . LYS A 1 32  ? 120.148 146.908 137.457 1.00 65.17  ?  35  LYS C CA  1 
ATOM   245  C C   . LYS A 1 32  ? 120.271 148.412 137.261 1.00 65.17  ?  35  LYS C C   1 
ATOM   246  O O   . LYS A 1 32  ? 121.118 148.871 136.487 1.00 65.17  ?  35  LYS C O   1 
ATOM   247  C CB  . LYS A 1 32  ? 121.441 146.336 138.037 1.00 65.17  ?  35  LYS C CB  1 
ATOM   248  C CG  . LYS A 1 32  ? 121.311 144.921 138.565 1.00 65.17  ?  35  LYS C CG  1 
ATOM   249  C CD  . LYS A 1 32  ? 122.675 144.305 138.820 1.00 65.17  ?  35  LYS C CD  1 
ATOM   250  C CE  . LYS A 1 32  ? 123.416 144.055 137.518 1.00 65.17  ?  35  LYS C CE  1 
ATOM   251  N NZ  . LYS A 1 32  ? 122.655 143.155 136.609 1.00 65.17  1  35  LYS C NZ  1 
ATOM   252  N N   . LEU A 1 33  ? 119.434 149.173 137.959 1.00 59.38  ?  36  LEU C N   1 
ATOM   253  C CA  . LEU A 1 33  ? 119.465 150.626 137.917 1.00 59.38  ?  36  LEU C CA  1 
ATOM   254  C C   . LEU A 1 33  ? 119.825 151.164 139.293 1.00 59.38  ?  36  LEU C C   1 
ATOM   255  O O   . LEU A 1 33  ? 119.411 150.607 140.314 1.00 59.38  ?  36  LEU C O   1 
ATOM   256  C CB  . LEU A 1 33  ? 118.117 151.198 137.473 1.00 59.38  ?  36  LEU C CB  1 
ATOM   257  C CG  . LEU A 1 33  ? 117.448 150.539 136.267 1.00 59.38  ?  36  LEU C CG  1 
ATOM   258  C CD1 . LEU A 1 33  ? 115.961 150.838 136.259 1.00 59.38  ?  36  LEU C CD1 1 
ATOM   259  C CD2 . LEU A 1 33  ? 118.095 151.010 134.980 1.00 59.38  ?  36  LEU C CD2 1 
ATOM   260  N N   . LEU A 1 34  ? 120.606 152.239 139.319 1.00 57.43  ?  37  LEU C N   1 
ATOM   261  C CA  . LEU A 1 34  ? 120.987 152.894 140.565 1.00 57.43  ?  37  LEU C CA  1 
ATOM   262  C C   . LEU A 1 34  ? 120.238 154.215 140.667 1.00 57.43  ?  37  LEU C C   1 
ATOM   263  O O   . LEU A 1 34  ? 120.439 155.106 139.838 1.00 57.43  ?  37  LEU C O   1 
ATOM   264  C CB  . LEU A 1 34  ? 122.497 153.119 140.627 1.00 57.43  ?  37  LEU C CB  1 
ATOM   265  C CG  . LEU A 1 34  ? 123.009 154.085 141.696 1.00 57.43  ?  37  LEU C CG  1 
ATOM   266  C CD1 . LEU A 1 34  ? 122.780 153.519 143.085 1.00 57.43  ?  37  LEU C CD1 1 
ATOM   267  C CD2 . LEU A 1 34  ? 124.480 154.388 141.478 1.00 57.43  ?  37  LEU C CD2 1 
ATOM   268  N N   . LEU A 1 35  ? 119.376 154.343 141.672 1.00 63.22  ?  38  LEU C N   1 
ATOM   269  C CA  . LEU A 1 35  ? 118.537 155.524 141.823 1.00 63.22  ?  38  LEU C CA  1 
ATOM   270  C C   . LEU A 1 35  ? 119.240 156.531 142.725 1.00 63.22  ?  38  LEU C C   1 
ATOM   271  O O   . LEU A 1 35  ? 119.577 156.216 143.871 1.00 63.22  ?  38  LEU C O   1 
ATOM   272  C CB  . LEU A 1 35  ? 117.174 155.142 142.396 1.00 63.22  ?  38  LEU C CB  1 
ATOM   273  C CG  . LEU A 1 35  ? 116.207 156.286 142.695 1.00 63.22  ?  38  LEU C CG  1 
ATOM   274  C CD1 . LEU A 1 35  ? 115.948 157.108 141.448 1.00 63.22  ?  38  LEU C CD1 1 
ATOM   275  C CD2 . LEU A 1 35  ? 114.907 155.746 143.258 1.00 63.22  ?  38  LEU C CD2 1 
ATOM   276  N N   . LEU A 1 36  ? 119.458 157.738 142.209 1.00 65.21  ?  39  LEU C N   1 
ATOM   277  C CA  . LEU A 1 36  ? 120.148 158.789 142.938 1.00 65.21  ?  39  LEU C CA  1 
ATOM   278  C C   . LEU A 1 36  ? 119.329 160.070 142.896 1.00 65.21  ?  39  LEU C C   1 
ATOM   279  O O   . LEU A 1 36  ? 118.524 160.294 141.988 1.00 65.21  ?  39  LEU C O   1 
ATOM   280  C CB  . LEU A 1 36  ? 121.548 159.044 142.366 1.00 65.21  ?  39  LEU C CB  1 
ATOM   281  C CG  . LEU A 1 36  ? 122.618 158.014 142.727 1.00 65.21  ?  39  LEU C CG  1 
ATOM   282  C CD1 . LEU A 1 36  ? 123.785 158.093 141.763 1.00 65.21  ?  39  LEU C CD1 1 
ATOM   283  C CD2 . LEU A 1 36  ? 123.091 158.221 144.153 1.00 65.21  ?  39  LEU C CD2 1 
ATOM   284  N N   . GLY A 1 37  ? 119.545 160.909 143.902 1.00 79.93  ?  40  GLY C N   1 
ATOM   285  C CA  . GLY A 1 37  ? 118.845 162.176 143.998 1.00 79.93  ?  40  GLY C CA  1 
ATOM   286  C C   . GLY A 1 37  ? 119.405 162.989 145.142 1.00 79.93  ?  40  GLY C C   1 
ATOM   287  O O   . GLY A 1 37  ? 120.274 162.536 145.891 1.00 79.93  ?  40  GLY C O   1 
ATOM   288  N N   . ALA A 1 38  ? 118.887 164.210 145.272 1.00 92.04  ?  41  ALA C N   1 
ATOM   289  C CA  . ALA A 1 38  ? 119.329 165.142 146.299 1.00 92.04  ?  41  ALA C CA  1 
ATOM   290  C C   . ALA A 1 38  ? 118.429 165.125 147.529 1.00 92.04  ?  41  ALA C C   1 
ATOM   291  O O   . ALA A 1 38  ? 118.455 166.074 148.321 1.00 92.04  ?  41  ALA C O   1 
ATOM   292  C CB  . ALA A 1 38  ? 119.415 166.557 145.727 1.00 92.04  ?  41  ALA C CB  1 
ATOM   293  N N   . GLY A 1 39  ? 117.636 164.072 147.705 1.00 98.30  ?  42  GLY C N   1 
ATOM   294  C CA  . GLY A 1 39  ? 116.732 163.991 148.833 1.00 98.30  ?  42  GLY C CA  1 
ATOM   295  C C   . GLY A 1 39  ? 115.425 164.708 148.573 1.00 98.30  ?  42  GLY C C   1 
ATOM   296  O O   . GLY A 1 39  ? 115.428 165.855 148.115 1.00 98.30  ?  42  GLY C O   1 
ATOM   297  N N   . GLU A 1 40  ? 114.306 164.034 148.864 1.00 103.09 ?  43  GLU C N   1 
ATOM   298  C CA  . GLU A 1 40  ? 112.945 164.518 148.633 1.00 103.09 ?  43  GLU C CA  1 
ATOM   299  C C   . GLU A 1 40  ? 112.818 165.265 147.308 1.00 103.09 ?  43  GLU C C   1 
ATOM   300  O O   . GLU A 1 40  ? 112.140 166.294 147.224 1.00 103.09 ?  43  GLU C O   1 
ATOM   301  C CB  . GLU A 1 40  ? 112.462 165.389 149.805 1.00 103.09 ?  43  GLU C CB  1 
ATOM   302  C CG  . GLU A 1 40  ? 113.244 166.668 150.080 1.00 103.09 ?  43  GLU C CG  1 
ATOM   303  C CD  . GLU A 1 40  ? 114.270 166.499 151.184 1.00 103.09 ?  43  GLU C CD  1 
ATOM   304  O OE1 . GLU A 1 40  ? 114.552 165.342 151.563 1.00 103.09 ?  43  GLU C OE1 1 
ATOM   305  O OE2 . GLU A 1 40  ? 114.794 167.522 151.672 1.00 103.09 -1 43  GLU C OE2 1 
ATOM   306  N N   . SER A 1 41  ? 113.457 164.738 146.263 1.00 95.09  ?  44  SER C N   1 
ATOM   307  C CA  . SER A 1 41  ? 113.442 165.342 144.937 1.00 95.09  ?  44  SER C CA  1 
ATOM   308  C C   . SER A 1 41  ? 112.614 164.533 143.946 1.00 95.09  ?  44  SER C C   1 
ATOM   309  O O   . SER A 1 41  ? 112.831 164.632 142.735 1.00 95.09  ?  44  SER C O   1 
ATOM   310  C CB  . SER A 1 41  ? 114.869 165.515 144.419 1.00 95.09  ?  44  SER C CB  1 
ATOM   311  O OG  . SER A 1 41  ? 115.570 164.284 144.440 1.00 95.09  ?  44  SER C OG  1 
ATOM   312  N N   . GLY A 1 42  ? 111.673 163.733 144.436 1.00 94.26  ?  45  GLY C N   1 
ATOM   313  C CA  . GLY A 1 42  ? 110.845 162.910 143.583 1.00 94.26  ?  45  GLY C CA  1 
ATOM   314  C C   . GLY A 1 42  ? 111.242 161.455 143.493 1.00 94.26  ?  45  GLY C C   1 
ATOM   315  O O   . GLY A 1 42  ? 110.638 160.718 142.705 1.00 94.26  ?  45  GLY C O   1 
ATOM   316  N N   . LYS A 1 43  ? 112.239 161.017 144.266 1.00 90.40  ?  46  LYS C N   1 
ATOM   317  C CA  . LYS A 1 43  ? 112.623 159.609 144.249 1.00 90.40  ?  46  LYS C CA  1 
ATOM   318  C C   . LYS A 1 43  ? 111.483 158.724 144.735 1.00 90.40  ?  46  LYS C C   1 
ATOM   319  O O   . LYS A 1 43  ? 111.236 157.650 144.172 1.00 90.40  ?  46  LYS C O   1 
ATOM   320  C CB  . LYS A 1 43  ? 113.870 159.393 145.105 1.00 90.40  ?  46  LYS C CB  1 
ATOM   321  C CG  . LYS A 1 43  ? 115.138 159.990 144.521 1.00 90.40  ?  46  LYS C CG  1 
ATOM   322  C CD  . LYS A 1 43  ? 116.374 159.297 145.070 1.00 90.40  ?  46  LYS C CD  1 
ATOM   323  C CE  . LYS A 1 43  ? 116.500 159.498 146.571 1.00 90.40  ?  46  LYS C CE  1 
ATOM   324  N NZ  . LYS A 1 43  ? 116.748 160.924 146.920 1.00 90.40  1  46  LYS C NZ  1 
ATOM   325  N N   . SER A 1 44  ? 110.778 159.157 145.783 1.00 96.26  ?  47  SER C N   1 
ATOM   326  C CA  . SER A 1 44  ? 109.642 158.389 146.281 1.00 96.26  ?  47  SER C CA  1 
ATOM   327  C C   . SER A 1 44  ? 108.542 158.290 145.232 1.00 96.26  ?  47  SER C C   1 
ATOM   328  O O   . SER A 1 44  ? 107.946 157.222 145.047 1.00 96.26  ?  47  SER C O   1 
ATOM   329  C CB  . SER A 1 44  ? 109.106 159.021 147.565 1.00 96.26  ?  47  SER C CB  1 
ATOM   330  O OG  . SER A 1 44  ? 108.576 160.311 147.314 1.00 96.26  ?  47  SER C OG  1 
ATOM   331  N N   . THR A 1 45  ? 108.259 159.392 144.535 1.00 96.96  ?  48  THR C N   1 
ATOM   332  C CA  . THR A 1 45  ? 107.243 159.364 143.487 1.00 96.96  ?  48  THR C CA  1 
ATOM   333  C C   . THR A 1 45  ? 107.651 158.440 142.346 1.00 96.96  ?  48  THR C C   1 
ATOM   334  O O   . THR A 1 45  ? 106.823 157.689 141.819 1.00 96.96  ?  48  THR C O   1 
ATOM   335  C CB  . THR A 1 45  ? 106.986 160.778 142.966 1.00 96.96  ?  48  THR C CB  1 
ATOM   336  O OG1 . THR A 1 45  ? 106.804 161.671 144.071 1.00 96.96  ?  48  THR C OG1 1 
ATOM   337  C CG2 . THR A 1 45  ? 105.742 160.805 142.091 1.00 96.96  ?  48  THR C CG2 1 
ATOM   338  N N   . ILE A 1 46  ? 108.926 158.482 141.953 1.00 94.27  ?  49  ILE C N   1 
ATOM   339  C CA  . ILE A 1 46  ? 109.407 157.608 140.886 1.00 94.27  ?  49  ILE C CA  1 
ATOM   340  C C   . ILE A 1 46  ? 109.288 156.147 141.300 1.00 94.27  ?  49  ILE C C   1 
ATOM   341  O O   . ILE A 1 46  ? 108.865 155.295 140.509 1.00 94.27  ?  49  ILE C O   1 
ATOM   342  C CB  . ILE A 1 46  ? 110.853 157.976 140.504 1.00 94.27  ?  49  ILE C CB  1 
ATOM   343  C CG1 . ILE A 1 46  ? 110.881 159.309 139.755 1.00 94.27  ?  49  ILE C CG1 1 
ATOM   344  C CG2 . ILE A 1 46  ? 111.485 156.880 139.662 1.00 94.27  ?  49  ILE C CG2 1 
ATOM   345  C CD1 . ILE A 1 46  ? 110.031 159.324 138.505 1.00 94.27  ?  49  ILE C CD1 1 
ATOM   346  N N   . VAL A 1 47  ? 109.652 155.835 142.546 1.00 96.34  ?  50  VAL C N   1 
ATOM   347  C CA  . VAL A 1 47  ? 109.527 154.465 143.039 1.00 96.34  ?  50  VAL C CA  1 
ATOM   348  C C   . VAL A 1 47  ? 108.067 154.032 143.045 1.00 96.34  ?  50  VAL C C   1 
ATOM   349  O O   . VAL A 1 47  ? 107.736 152.902 142.665 1.00 96.34  ?  50  VAL C O   1 
ATOM   350  C CB  . VAL A 1 47  ? 110.165 154.343 144.436 1.00 96.34  ?  50  VAL C CB  1 
ATOM   351  C CG1 . VAL A 1 47  ? 109.685 153.081 145.138 1.00 96.34  ?  50  VAL C CG1 1 
ATOM   352  C CG2 . VAL A 1 47  ? 111.679 154.350 144.327 1.00 96.34  ?  50  VAL C CG2 1 
ATOM   353  N N   . LYS A 1 48  ? 107.169 154.925 143.470 1.00 99.22  ?  51  LYS C N   1 
ATOM   354  C CA  . LYS A 1 48  ? 105.747 154.598 143.494 1.00 99.22  ?  51  LYS C CA  1 
ATOM   355  C C   . LYS A 1 48  ? 105.218 154.332 142.089 1.00 99.22  ?  51  LYS C C   1 
ATOM   356  O O   . LYS A 1 48  ? 104.404 153.423 141.887 1.00 99.22  ?  51  LYS C O   1 
ATOM   357  C CB  . LYS A 1 48  ? 104.968 155.729 144.171 1.00 99.22  ?  51  LYS C CB  1 
ATOM   358  C CG  . LYS A 1 48  ? 103.460 155.513 144.286 1.00 99.22  ?  51  LYS C CG  1 
ATOM   359  C CD  . LYS A 1 48  ? 102.698 156.133 143.119 1.00 99.22  ?  51  LYS C CD  1 
ATOM   360  C CE  . LYS A 1 48  ? 102.720 157.651 143.189 1.00 99.22  ?  51  LYS C CE  1 
ATOM   361  N NZ  . LYS A 1 48  ? 101.969 158.268 142.060 1.00 99.22  1  51  LYS C NZ  1 
ATOM   362  N N   . GLN A 1 49  ? 105.668 155.114 141.105 1.00 98.76  ?  52  GLN C N   1 
ATOM   363  C CA  . GLN A 1 49  ? 105.199 154.932 139.736 1.00 98.76  ?  52  GLN C CA  1 
ATOM   364  C C   . GLN A 1 49  ? 105.669 153.619 139.122 1.00 98.76  ?  52  GLN C C   1 
ATOM   365  O O   . GLN A 1 49  ? 105.137 153.213 138.083 1.00 98.76  ?  52  GLN C O   1 
ATOM   366  C CB  . GLN A 1 49  ? 105.652 156.101 138.862 1.00 98.76  ?  52  GLN C CB  1 
ATOM   367  C CG  . GLN A 1 49  ? 105.012 157.429 139.225 1.00 98.76  ?  52  GLN C CG  1 
ATOM   368  C CD  . GLN A 1 49  ? 105.500 158.564 138.351 1.00 98.76  ?  52  GLN C CD  1 
ATOM   369  O OE1 . GLN A 1 49  ? 106.374 158.378 137.506 1.00 98.76  ?  52  GLN C OE1 1 
ATOM   370  N NE2 . GLN A 1 49  ? 104.937 159.750 138.550 1.00 98.76  ?  52  GLN C NE2 1 
ATOM   371  N N   . MET A 1 50  ? 106.644 152.951 139.729 1.00 93.72  ?  53  MET C N   1 
ATOM   372  C CA  . MET A 1 50  ? 107.114 151.667 139.222 1.00 93.72  ?  53  MET C CA  1 
ATOM   373  C C   . MET A 1 50  ? 107.624 150.785 140.357 1.00 93.72  ?  53  MET C C   1 
ATOM   374  O O   . MET A 1 50  ? 106.840 150.145 141.058 1.00 93.72  ?  53  MET C O   1 
ATOM   375  C CB  . MET A 1 50  ? 108.214 151.870 138.178 1.00 93.72  ?  53  MET C CB  1 
ATOM   376  C CG  . MET A 1 50  ? 109.370 152.733 138.651 1.00 93.72  ?  53  MET C CG  1 
ATOM   377  S SD  . MET A 1 50  ? 110.263 153.524 137.300 1.00 93.72  ?  53  MET C SD  1 
ATOM   378  C CE  . MET A 1 50  ? 109.108 154.812 136.841 1.00 93.72  ?  53  MET C CE  1 
ATOM   379  N N   . THR A 1 179 ? 116.936 151.439 156.108 1.00 76.65  ?  182 THR C N   1 
ATOM   380  C CA  . THR A 1 179 ? 118.261 151.499 156.713 1.00 76.65  ?  182 THR C CA  1 
ATOM   381  C C   . THR A 1 179 ? 119.346 151.640 155.651 1.00 76.65  ?  182 THR C C   1 
ATOM   382  O O   . THR A 1 179 ? 119.935 152.708 155.489 1.00 76.65  ?  182 THR C O   1 
ATOM   383  C CB  . THR A 1 179 ? 118.551 150.249 157.565 1.00 76.65  ?  182 THR C CB  1 
ATOM   384  O OG1 . THR A 1 179 ? 118.286 149.070 156.794 1.00 76.65  ?  182 THR C OG1 1 
ATOM   385  C CG2 . THR A 1 179 ? 117.681 150.241 158.811 1.00 76.65  ?  182 THR C CG2 1 
ATOM   386  N N   . GLY A 1 180 ? 119.608 150.553 154.929 1.00 73.31  ?  183 GLY C N   1 
ATOM   387  C CA  . GLY A 1 180 ? 120.634 150.558 153.907 1.00 73.31  ?  183 GLY C CA  1 
ATOM   388  C C   . GLY A 1 180 ? 120.082 150.641 152.500 1.00 73.31  ?  183 GLY C C   1 
ATOM   389  O O   . GLY A 1 180 ? 119.245 151.498 152.203 1.00 73.31  ?  183 GLY C O   1 
ATOM   390  N N   . ILE A 1 181 ? 120.551 149.754 151.622 1.00 68.59  ?  184 ILE C N   1 
ATOM   391  C CA  . ILE A 1 181 ? 120.073 149.732 150.247 1.00 68.59  ?  184 ILE C CA  1 
ATOM   392  C C   . ILE A 1 181 ? 118.606 149.330 150.224 1.00 68.59  ?  184 ILE C C   1 
ATOM   393  O O   . ILE A 1 181 ? 118.187 148.394 150.918 1.00 68.59  ?  184 ILE C O   1 
ATOM   394  C CB  . ILE A 1 181 ? 120.920 148.767 149.400 1.00 68.59  ?  184 ILE C CB  1 
ATOM   395  C CG1 . ILE A 1 181 ? 122.385 149.188 149.421 1.00 68.59  ?  184 ILE C CG1 1 
ATOM   396  C CG2 . ILE A 1 181 ? 120.415 148.721 147.969 1.00 68.59  ?  184 ILE C CG2 1 
ATOM   397  C CD1 . ILE A 1 181 ? 122.630 150.554 148.855 1.00 68.59  ?  184 ILE C CD1 1 
ATOM   398  N N   . VAL A 1 182 ? 117.813 150.039 149.428 1.00 69.63  ?  185 VAL C N   1 
ATOM   399  C CA  . VAL A 1 182 ? 116.413 149.691 149.211 1.00 69.63  ?  185 VAL C CA  1 
ATOM   400  C C   . VAL A 1 182 ? 116.297 149.156 147.791 1.00 69.63  ?  185 VAL C C   1 
ATOM   401  O O   . VAL A 1 182 ? 116.515 149.891 146.822 1.00 69.63  ?  185 VAL C O   1 
ATOM   402  C CB  . VAL A 1 182 ? 115.482 150.888 149.436 1.00 69.63  ?  185 VAL C CB  1 
ATOM   403  C CG1 . VAL A 1 182 ? 114.031 150.449 149.358 1.00 69.63  ?  185 VAL C CG1 1 
ATOM   404  C CG2 . VAL A 1 182 ? 115.773 151.536 150.779 1.00 69.63  ?  185 VAL C CG2 1 
ATOM   405  N N   . GLU A 1 183 ? 115.959 147.878 147.658 1.00 72.58  ?  186 GLU C N   1 
ATOM   406  C CA  . GLU A 1 183 ? 115.850 147.236 146.356 1.00 72.58  ?  186 GLU C CA  1 
ATOM   407  C C   . GLU A 1 183 ? 114.385 147.123 145.963 1.00 72.58  ?  186 GLU C C   1 
ATOM   408  O O   . GLU A 1 183 ? 113.579 146.554 146.707 1.00 72.58  ?  186 GLU C O   1 
ATOM   409  C CB  . GLU A 1 183 ? 116.503 145.854 146.371 1.00 72.58  ?  186 GLU C CB  1 
ATOM   410  C CG  . GLU A 1 183 ? 117.996 145.879 146.640 1.00 72.58  ?  186 GLU C CG  1 
ATOM   411  C CD  . GLU A 1 183 ? 118.693 144.620 146.166 1.00 72.58  ?  186 GLU C CD  1 
ATOM   412  O OE1 . GLU A 1 183 ? 118.286 144.072 145.121 1.00 72.58  ?  186 GLU C OE1 1 
ATOM   413  O OE2 . GLU A 1 183 ? 119.648 144.177 146.840 1.00 72.58  -1 186 GLU C OE2 1 
ATOM   414  N N   . THR A 1 184 ? 114.044 147.665 144.797 1.00 73.68  ?  187 THR C N   1 
ATOM   415  C CA  . THR A 1 184 ? 112.685 147.616 144.273 1.00 73.68  ?  187 THR C CA  1 
ATOM   416  C C   . THR A 1 184 ? 112.702 146.876 142.944 1.00 73.68  ?  187 THR C C   1 
ATOM   417  O O   . THR A 1 184 ? 113.398 147.287 142.012 1.00 73.68  ?  187 THR C O   1 
ATOM   418  C CB  . THR A 1 184 ? 112.109 149.022 144.097 1.00 73.68  ?  187 THR C CB  1 
ATOM   419  O OG1 . THR A 1 184 ? 111.963 149.642 145.380 1.00 73.68  ?  187 THR C OG1 1 
ATOM   420  C CG2 . THR A 1 184 ? 110.754 148.960 143.414 1.00 73.68  ?  187 THR C CG2 1 
ATOM   421  N N   . HIS A 1 185 ? 111.933 145.796 142.855 1.00 77.04  ?  188 HIS C N   1 
ATOM   422  C CA  . HIS A 1 185 ? 111.872 144.966 141.660 1.00 77.04  ?  188 HIS C CA  1 
ATOM   423  C C   . HIS A 1 185 ? 110.553 145.209 140.942 1.00 77.04  ?  188 HIS C C   1 
ATOM   424  O O   . HIS A 1 185 ? 109.492 145.211 141.575 1.00 77.04  ?  188 HIS C O   1 
ATOM   425  C CB  . HIS A 1 185 ? 112.010 143.484 142.013 1.00 77.04  ?  188 HIS C CB  1 
ATOM   426  C CG  . HIS A 1 185 ? 113.365 143.105 142.524 1.00 77.04  ?  188 HIS C CG  1 
ATOM   427  N ND1 . HIS A 1 185 ? 113.813 141.802 142.544 1.00 77.04  ?  188 HIS C ND1 1 
ATOM   428  C CD2 . HIS A 1 185 ? 114.369 143.856 143.034 1.00 77.04  ?  188 HIS C CD2 1 
ATOM   429  C CE1 . HIS A 1 185 ? 115.035 141.766 143.044 1.00 77.04  ?  188 HIS C CE1 1 
ATOM   430  N NE2 . HIS A 1 185 ? 115.396 142.999 143.349 1.00 77.04  ?  188 HIS C NE2 1 
ATOM   431  N N   . PHE A 1 186 ? 110.618 145.416 139.629 1.00 77.52  ?  189 PHE C N   1 
ATOM   432  C CA  . PHE A 1 186 ? 109.398 145.548 138.844 1.00 77.52  ?  189 PHE C CA  1 
ATOM   433  C C   . PHE A 1 186 ? 109.627 145.015 137.438 1.00 77.52  ?  189 PHE C C   1 
ATOM   434  O O   . PHE A 1 186 ? 110.722 145.144 136.886 1.00 77.52  ?  189 PHE C O   1 
ATOM   435  C CB  . PHE A 1 186 ? 108.902 147.000 138.801 1.00 77.52  ?  189 PHE C CB  1 
ATOM   436  C CG  . PHE A 1 186 ? 109.798 147.938 138.045 1.00 77.52  ?  189 PHE C CG  1 
ATOM   437  C CD1 . PHE A 1 186 ? 110.881 148.536 138.666 1.00 77.52  ?  189 PHE C CD1 1 
ATOM   438  C CD2 . PHE A 1 186 ? 109.540 148.246 136.720 1.00 77.52  ?  189 PHE C CD2 1 
ATOM   439  C CE1 . PHE A 1 186 ? 111.699 149.407 137.975 1.00 77.52  ?  189 PHE C CE1 1 
ATOM   440  C CE2 . PHE A 1 186 ? 110.355 149.116 136.024 1.00 77.52  ?  189 PHE C CE2 1 
ATOM   441  C CZ  . PHE A 1 186 ? 111.434 149.699 136.652 1.00 77.52  ?  189 PHE C CZ  1 
ATOM   442  N N   . THR A 1 187 ? 108.587 144.419 136.865 1.00 80.81  ?  190 THR C N   1 
ATOM   443  C CA  . THR A 1 187 ? 108.658 143.798 135.550 1.00 80.81  ?  190 THR C CA  1 
ATOM   444  C C   . THR A 1 187 ? 107.885 144.634 134.541 1.00 80.81  ?  190 THR C C   1 
ATOM   445  O O   . THR A 1 187 ? 106.731 145.002 134.785 1.00 80.81  ?  190 THR C O   1 
ATOM   446  C CB  . THR A 1 187 ? 108.104 142.372 135.586 1.00 80.81  ?  190 THR C CB  1 
ATOM   447  O OG1 . THR A 1 187 ? 108.595 141.696 136.750 1.00 80.81  ?  190 THR C OG1 1 
ATOM   448  C CG2 . THR A 1 187 ? 108.533 141.606 134.346 1.00 80.81  ?  190 THR C CG2 1 
ATOM   449  N N   . PHE A 1 188 ? 108.526 144.930 133.414 1.00 77.99  ?  191 PHE C N   1 
ATOM   450  C CA  . PHE A 1 188 ? 107.912 145.672 132.323 1.00 77.99  ?  191 PHE C CA  1 
ATOM   451  C C   . PHE A 1 188 ? 108.333 145.043 131.005 1.00 77.99  ?  191 PHE C C   1 
ATOM   452  O O   . PHE A 1 188 ? 109.530 144.889 130.746 1.00 77.99  ?  191 PHE C O   1 
ATOM   453  C CB  . PHE A 1 188 ? 108.316 147.150 132.359 1.00 77.99  ?  191 PHE C CB  1 
ATOM   454  C CG  . PHE A 1 188 ? 107.500 148.023 131.453 1.00 77.99  ?  191 PHE C CG  1 
ATOM   455  C CD1 . PHE A 1 188 ? 106.188 148.334 131.765 1.00 77.99  ?  191 PHE C CD1 1 
ATOM   456  C CD2 . PHE A 1 188 ? 108.046 148.537 130.289 1.00 77.99  ?  191 PHE C CD2 1 
ATOM   457  C CE1 . PHE A 1 188 ? 105.437 149.140 130.933 1.00 77.99  ?  191 PHE C CE1 1 
ATOM   458  C CE2 . PHE A 1 188 ? 107.299 149.342 129.454 1.00 77.99  ?  191 PHE C CE2 1 
ATOM   459  C CZ  . PHE A 1 188 ? 105.993 149.644 129.776 1.00 77.99  ?  191 PHE C CZ  1 
ATOM   460  N N   . LYS A 1 189 ? 107.347 144.682 130.183 1.00 78.58  ?  192 LYS C N   1 
ATOM   461  C CA  . LYS A 1 189 ? 107.579 144.076 128.872 1.00 78.58  ?  192 LYS C CA  1 
ATOM   462  C C   . LYS A 1 189 ? 108.520 142.877 128.976 1.00 78.58  ?  192 LYS C C   1 
ATOM   463  O O   . LYS A 1 189 ? 109.484 142.741 128.218 1.00 78.58  ?  192 LYS C O   1 
ATOM   464  C CB  . LYS A 1 189 ? 108.111 145.110 127.880 1.00 78.58  ?  192 LYS C CB  1 
ATOM   465  C CG  . LYS A 1 189 ? 107.080 146.143 127.457 1.00 78.58  ?  192 LYS C CG  1 
ATOM   466  C CD  . LYS A 1 189 ? 107.540 146.915 126.234 1.00 78.58  ?  192 LYS C CD  1 
ATOM   467  C CE  . LYS A 1 189 ? 106.580 148.044 125.902 1.00 78.58  ?  192 LYS C CE  1 
ATOM   468  N NZ  . LYS A 1 189 ? 105.223 147.535 125.560 1.00 78.58  1  192 LYS C NZ  1 
ATOM   469  N N   . ASP A 1 190 ? 108.230 142.005 129.943 1.00 79.11  ?  193 ASP C N   1 
ATOM   470  C CA  . ASP A 1 190 ? 109.006 140.788 130.187 1.00 79.11  ?  193 ASP C CA  1 
ATOM   471  C C   . ASP A 1 190 ? 110.467 141.096 130.506 1.00 79.11  ?  193 ASP C C   1 
ATOM   472  O O   . ASP A 1 190 ? 111.358 140.292 130.220 1.00 79.11  ?  193 ASP C O   1 
ATOM   473  C CB  . ASP A 1 190 ? 108.910 139.817 129.006 1.00 79.11  ?  193 ASP C CB  1 
ATOM   474  N N   . LEU A 1 191 ? 110.726 142.258 131.101 1.00 77.23  ?  194 LEU C N   1 
ATOM   475  C CA  . LEU A 1 191 ? 112.064 142.638 131.531 1.00 77.23  ?  194 LEU C CA  1 
ATOM   476  C C   . LEU A 1 191 ? 112.017 142.996 133.008 1.00 77.23  ?  194 LEU C C   1 
ATOM   477  O O   . LEU A 1 191 ? 111.163 143.779 133.429 1.00 77.23  ?  194 LEU C O   1 
ATOM   478  C CB  . LEU A 1 191 ? 112.600 143.816 130.713 1.00 77.23  ?  194 LEU C CB  1 
ATOM   479  C CG  . LEU A 1 191 ? 114.118 144.001 130.717 1.00 77.23  ?  194 LEU C CG  1 
ATOM   480  C CD1 . LEU A 1 191 ? 114.815 142.709 130.325 1.00 77.23  ?  194 LEU C CD1 1 
ATOM   481  C CD2 . LEU A 1 191 ? 114.521 145.132 129.788 1.00 77.23  ?  194 LEU C CD2 1 
ATOM   482  N N   . HIS A 1 192 ? 112.934 142.431 133.786 1.00 78.33  ?  195 HIS C N   1 
ATOM   483  C CA  . HIS A 1 192 ? 112.960 142.620 135.231 1.00 78.33  ?  195 HIS C CA  1 
ATOM   484  C C   . HIS A 1 192 ? 113.972 143.703 135.579 1.00 78.33  ?  195 HIS C C   1 
ATOM   485  O O   . HIS A 1 192 ? 115.164 143.559 135.290 1.00 78.33  ?  195 HIS C O   1 
ATOM   486  C CB  . HIS A 1 192 ? 113.309 141.311 135.939 1.00 78.33  ?  195 HIS C CB  1 
ATOM   487  C CG  . HIS A 1 192 ? 112.864 141.257 137.367 1.00 78.33  ?  195 HIS C CG  1 
ATOM   488  N ND1 . HIS A 1 192 ? 113.702 140.882 138.394 1.00 78.33  ?  195 HIS C ND1 1 
ATOM   489  C CD2 . HIS A 1 192 ? 111.667 141.528 137.939 1.00 78.33  ?  195 HIS C CD2 1 
ATOM   490  C CE1 . HIS A 1 192 ? 113.042 140.926 139.538 1.00 78.33  ?  195 HIS C CE1 1 
ATOM   491  N NE2 . HIS A 1 192 ? 111.804 141.315 139.289 1.00 78.33  ?  195 HIS C NE2 1 
ATOM   492  N N   . PHE A 1 193 ? 113.498 144.782 136.199 1.00 73.99  ?  196 PHE C N   1 
ATOM   493  C CA  . PHE A 1 193 ? 114.341 145.883 136.634 1.00 73.99  ?  196 PHE C CA  1 
ATOM   494  C C   . PHE A 1 193 ? 114.446 145.874 138.151 1.00 73.99  ?  196 PHE C C   1 
ATOM   495  O O   . PHE A 1 193 ? 113.447 145.671 138.852 1.00 73.99  ?  196 PHE C O   1 
ATOM   496  C CB  . PHE A 1 193 ? 113.781 147.232 136.178 1.00 73.99  ?  196 PHE C CB  1 
ATOM   497  C CG  . PHE A 1 193 ? 113.541 147.335 134.701 1.00 73.99  ?  196 PHE C CG  1 
ATOM   498  C CD1 . PHE A 1 193 ? 112.349 146.903 134.148 1.00 73.99  ?  196 PHE C CD1 1 
ATOM   499  C CD2 . PHE A 1 193 ? 114.496 147.888 133.869 1.00 73.99  ?  196 PHE C CD2 1 
ATOM   500  C CE1 . PHE A 1 193 ? 112.123 147.005 132.792 1.00 73.99  ?  196 PHE C CE1 1 
ATOM   501  C CE2 . PHE A 1 193 ? 114.275 147.993 132.512 1.00 73.99  ?  196 PHE C CE2 1 
ATOM   502  C CZ  . PHE A 1 193 ? 113.086 147.551 131.974 1.00 73.99  ?  196 PHE C CZ  1 
ATOM   503  N N   . LYS A 1 194 ? 115.658 146.101 138.652 1.00 69.94  ?  197 LYS C N   1 
ATOM   504  C CA  . LYS A 1 194 ? 115.921 146.245 140.079 1.00 69.94  ?  197 LYS C CA  1 
ATOM   505  C C   . LYS A 1 194 ? 116.531 147.620 140.304 1.00 69.94  ?  197 LYS C C   1 
ATOM   506  O O   . LYS A 1 194 ? 117.651 147.888 139.855 1.00 69.94  ?  197 LYS C O   1 
ATOM   507  C CB  . LYS A 1 194 ? 116.856 145.150 140.587 1.00 69.94  ?  197 LYS C CB  1 
ATOM   508  C CG  . LYS A 1 194 ? 116.642 143.790 139.958 1.00 69.94  ?  197 LYS C CG  1 
ATOM   509  C CD  . LYS A 1 194 ? 117.448 142.730 140.686 1.00 69.94  ?  197 LYS C CD  1 
ATOM   510  C CE  . LYS A 1 194 ? 118.884 142.695 140.193 1.00 69.94  ?  197 LYS C CE  1 
ATOM   511  N NZ  . LYS A 1 194 ? 119.503 141.354 140.377 1.00 69.94  1  197 LYS C NZ  1 
ATOM   512  N N   . MET A 1 195 ? 115.796 148.488 140.991 1.00 70.84  ?  198 MET C N   1 
ATOM   513  C CA  . MET A 1 195 ? 116.296 149.801 141.368 1.00 70.84  ?  198 MET C CA  1 
ATOM   514  C C   . MET A 1 195 ? 116.900 149.725 142.762 1.00 70.84  ?  198 MET C C   1 
ATOM   515  O O   . MET A 1 195 ? 116.260 149.232 143.696 1.00 70.84  ?  198 MET C O   1 
ATOM   516  C CB  . MET A 1 195 ? 115.180 150.845 141.346 1.00 70.84  ?  198 MET C CB  1 
ATOM   517  C CG  . MET A 1 195 ? 114.612 151.142 139.976 1.00 70.84  ?  198 MET C CG  1 
ATOM   518  S SD  . MET A 1 195 ? 113.356 152.430 140.068 1.00 70.84  ?  198 MET C SD  1 
ATOM   519  C CE  . MET A 1 195 ? 112.002 151.522 140.807 1.00 70.84  ?  198 MET C CE  1 
ATOM   520  N N   . PHE A 1 196 ? 118.130 150.209 142.893 1.00 63.92  ?  199 PHE C N   1 
ATOM   521  C CA  . PHE A 1 196 ? 118.816 150.276 144.175 1.00 63.92  ?  199 PHE C CA  1 
ATOM   522  C C   . PHE A 1 196 ? 118.828 151.723 144.646 1.00 63.92  ?  199 PHE C C   1 
ATOM   523  O O   . PHE A 1 196 ? 119.411 152.589 143.986 1.00 63.92  ?  199 PHE C O   1 
ATOM   524  C CB  . PHE A 1 196 ? 120.241 149.735 144.064 1.00 63.92  ?  199 PHE C CB  1 
ATOM   525  C CG  . PHE A 1 196 ? 120.338 148.437 143.322 1.00 63.92  ?  199 PHE C CG  1 
ATOM   526  C CD1 . PHE A 1 196 ? 119.693 147.307 143.791 1.00 63.92  ?  199 PHE C CD1 1 
ATOM   527  C CD2 . PHE A 1 196 ? 121.075 148.345 142.155 1.00 63.92  ?  199 PHE C CD2 1 
ATOM   528  C CE1 . PHE A 1 196 ? 119.781 146.110 143.111 1.00 63.92  ?  199 PHE C CE1 1 
ATOM   529  C CE2 . PHE A 1 196 ? 121.166 147.152 141.471 1.00 63.92  ?  199 PHE C CE2 1 
ATOM   530  C CZ  . PHE A 1 196 ? 120.518 146.033 141.949 1.00 63.92  ?  199 PHE C CZ  1 
ATOM   531  N N   . ASP A 1 197 ? 118.179 151.980 145.778 1.00 69.99  ?  200 ASP C N   1 
ATOM   532  C CA  . ASP A 1 197 ? 118.114 153.304 146.377 1.00 69.99  ?  200 ASP C CA  1 
ATOM   533  C C   . ASP A 1 197 ? 119.095 153.372 147.538 1.00 69.99  ?  200 ASP C C   1 
ATOM   534  O O   . ASP A 1 197 ? 119.072 152.514 148.430 1.00 69.99  ?  200 ASP C O   1 
ATOM   535  C CB  . ASP A 1 197 ? 116.697 153.617 146.856 1.00 69.99  ?  200 ASP C CB  1 
ATOM   536  C CG  . ASP A 1 197 ? 116.525 155.066 147.259 1.00 69.99  ?  200 ASP C CG  1 
ATOM   537  O OD1 . ASP A 1 197 ? 117.412 155.884 146.938 1.00 69.99  ?  200 ASP C OD1 1 
ATOM   538  O OD2 . ASP A 1 197 ? 115.501 155.390 147.896 1.00 69.99  -1 200 ASP C OD2 1 
ATOM   539  N N   . VAL A 1 198 ? 119.948 154.392 147.520 1.00 70.78  ?  201 VAL C N   1 
ATOM   540  C CA  . VAL A 1 198 ? 121.027 154.549 148.484 1.00 70.78  ?  201 VAL C CA  1 
ATOM   541  C C   . VAL A 1 198 ? 120.784 155.750 149.399 1.00 70.78  ?  201 VAL C C   1 
ATOM   542  O O   . VAL A 1 198 ? 121.721 156.270 150.001 1.00 70.78  ?  201 VAL C O   1 
ATOM   543  C CB  . VAL A 1 198 ? 122.385 154.657 147.773 1.00 70.78  ?  201 VAL C CB  1 
ATOM   544  C CG1 . VAL A 1 198 ? 122.595 153.471 146.856 1.00 70.78  ?  201 VAL C CG1 1 
ATOM   545  C CG2 . VAL A 1 198 ? 122.464 155.949 146.977 1.00 70.78  ?  201 VAL C CG2 1 
ATOM   546  N N   . GLY A 1 199 ? 119.530 156.193 149.517 1.00 76.48  ?  202 GLY C N   1 
ATOM   547  C CA  . GLY A 1 199 ? 119.240 157.375 150.310 1.00 76.48  ?  202 GLY C CA  1 
ATOM   548  C C   . GLY A 1 199 ? 119.581 157.220 151.779 1.00 76.48  ?  202 GLY C C   1 
ATOM   549  O O   . GLY A 1 199 ? 119.975 158.189 152.434 1.00 76.48  ?  202 GLY C O   1 
ATOM   550  N N   . ALA A 1 200 ? 119.440 156.009 152.317 1.00 79.28  ?  203 ALA C N   1 
ATOM   551  C CA  . ALA A 1 200 ? 119.722 155.779 153.722 1.00 79.28  ?  203 ALA C CA  1 
ATOM   552  C C   . ALA A 1 200 ? 121.194 155.768 154.080 1.00 79.28  ?  203 ALA C C   1 
ATOM   553  O O   . ALA A 1 200 ? 121.521 155.781 155.272 1.00 79.28  ?  203 ALA C O   1 
ATOM   554  N N   . GLN A 1 201 ? 122.082 155.745 153.089 1.00 77.01  ?  204 GLN C N   1 
ATOM   555  C CA  . GLN A 1 201 ? 123.523 155.736 153.336 1.00 77.01  ?  204 GLN C CA  1 
ATOM   556  C C   . GLN A 1 201 ? 123.994 157.169 153.545 1.00 77.01  ?  204 GLN C C   1 
ATOM   557  O O   . GLN A 1 201 ? 124.176 157.923 152.587 1.00 77.01  ?  204 GLN C O   1 
ATOM   558  C CB  . GLN A 1 201 ? 124.260 155.075 152.177 1.00 77.01  ?  204 GLN C CB  1 
ATOM   559  C CG  . GLN A 1 201 ? 123.950 153.599 152.003 1.00 77.01  ?  204 GLN C CG  1 
ATOM   560  C CD  . GLN A 1 201 ? 124.368 152.773 153.202 1.00 77.01  ?  204 GLN C CD  1 
ATOM   561  O OE1 . GLN A 1 201 ? 123.528 152.279 153.954 1.00 77.01  ?  204 GLN C OE1 1 
ATOM   562  N NE2 . GLN A 1 201 ? 125.672 152.621 153.389 1.00 77.01  ?  204 GLN C NE2 1 
ATOM   563  N N   . ARG A 1 202 ? 124.196 157.548 154.804 1.00 83.58  ?  205 ARG C N   1 
ATOM   564  C CA  . ARG A 1 202 ? 124.688 158.874 155.152 1.00 83.58  ?  205 ARG C CA  1 
ATOM   565  C C   . ARG A 1 202 ? 126.205 158.929 155.271 1.00 83.58  ?  205 ARG C C   1 
ATOM   566  O O   . ARG A 1 202 ? 126.747 159.985 155.612 1.00 83.58  ?  205 ARG C O   1 
ATOM   567  C CB  . ARG A 1 202 ? 124.052 159.345 156.464 1.00 83.58  ?  205 ARG C CB  1 
ATOM   568  C CG  . ARG A 1 202 ? 122.534 159.423 156.427 1.00 83.58  ?  205 ARG C CG  1 
ATOM   569  C CD  . ARG A 1 202 ? 122.056 160.823 156.070 1.00 83.58  ?  205 ARG C CD  1 
ATOM   570  N NE  . ARG A 1 202 ? 122.325 161.158 154.677 1.00 83.58  ?  205 ARG C NE  1 
ATOM   571  C CZ  . ARG A 1 202 ? 121.563 160.788 153.656 1.00 83.58  ?  205 ARG C CZ  1 
ATOM   572  N NH1 . ARG A 1 202 ? 120.468 160.068 153.836 1.00 83.58  1  205 ARG C NH1 1 
ATOM   573  N NH2 . ARG A 1 202 ? 121.909 161.149 152.424 1.00 83.58  ?  205 ARG C NH2 1 
ATOM   574  N N   . SER A 1 203 ? 126.896 157.827 154.999 1.00 77.25  ?  206 SER C N   1 
ATOM   575  C CA  . SER A 1 203 ? 128.347 157.770 155.114 1.00 77.25  ?  206 SER C CA  1 
ATOM   576  C C   . SER A 1 203 ? 128.989 158.376 153.867 1.00 77.25  ?  206 SER C C   1 
ATOM   577  O O   . SER A 1 203 ? 128.326 159.005 153.037 1.00 77.25  ?  206 SER C O   1 
ATOM   578  C CB  . SER A 1 203 ? 128.795 156.330 155.343 1.00 77.25  ?  206 SER C CB  1 
ATOM   579  O OG  . SER A 1 203 ? 128.431 155.516 154.243 1.00 77.25  ?  206 SER C OG  1 
ATOM   580  N N   . GLU A 1 204 ? 130.299 158.192 153.723 1.00 78.12  ?  207 GLU C N   1 
ATOM   581  C CA  . GLU A 1 204 ? 131.006 158.718 152.564 1.00 78.12  ?  207 GLU C CA  1 
ATOM   582  C C   . GLU A 1 204 ? 130.674 157.891 151.328 1.00 78.12  ?  207 GLU C C   1 
ATOM   583  O O   . GLU A 1 204 ? 130.780 156.661 151.342 1.00 78.12  ?  207 GLU C O   1 
ATOM   584  C CB  . GLU A 1 204 ? 132.512 158.720 152.815 1.00 78.12  ?  207 GLU C CB  1 
ATOM   585  C CG  . GLU A 1 204 ? 133.321 159.395 151.722 1.00 78.12  ?  207 GLU C CG  1 
ATOM   586  C CD  . GLU A 1 204 ? 133.076 160.889 151.651 1.00 78.12  ?  207 GLU C CD  1 
ATOM   587  O OE1 . GLU A 1 204 ? 132.774 161.495 152.700 1.00 78.12  ?  207 GLU C OE1 1 
ATOM   588  O OE2 . GLU A 1 204 ? 133.184 161.458 150.544 1.00 78.12  -1 207 GLU C OE2 1 
ATOM   589  N N   . ARG A 1 205 ? 130.274 158.574 150.255 1.00 74.60  ?  208 ARG C N   1 
ATOM   590  C CA  . ARG A 1 205 ? 129.824 157.875 149.056 1.00 74.60  ?  208 ARG C CA  1 
ATOM   591  C C   . ARG A 1 205 ? 130.978 157.178 148.345 1.00 74.60  ?  208 ARG C C   1 
ATOM   592  O O   . ARG A 1 205 ? 130.806 156.079 147.805 1.00 74.60  ?  208 ARG C O   1 
ATOM   593  C CB  . ARG A 1 205 ? 129.124 158.853 148.115 1.00 74.60  ?  208 ARG C CB  1 
ATOM   594  C CG  . ARG A 1 205 ? 128.504 158.205 146.891 1.00 74.60  ?  208 ARG C CG  1 
ATOM   595  C CD  . ARG A 1 205 ? 127.770 159.228 146.043 1.00 74.60  ?  208 ARG C CD  1 
ATOM   596  N NE  . ARG A 1 205 ? 128.678 160.222 145.486 1.00 74.60  ?  208 ARG C NE  1 
ATOM   597  C CZ  . ARG A 1 205 ? 128.675 161.506 145.816 1.00 74.60  ?  208 ARG C CZ  1 
ATOM   598  N NH1 . ARG A 1 205 ? 127.818 161.990 146.700 1.00 74.60  1  208 ARG C NH1 1 
ATOM   599  N NH2 . ARG A 1 205 ? 129.553 162.325 145.245 1.00 74.60  ?  208 ARG C NH2 1 
ATOM   600  N N   . LYS A 1 206 ? 132.160 157.795 148.336 1.00 74.57  ?  209 LYS C N   1 
ATOM   601  C CA  . LYS A 1 206 ? 133.282 157.252 147.578 1.00 74.57  ?  209 LYS C CA  1 
ATOM   602  C C   . LYS A 1 206 ? 133.812 155.943 148.147 1.00 74.57  ?  209 LYS C C   1 
ATOM   603  O O   . LYS A 1 206 ? 134.607 155.278 147.476 1.00 74.57  ?  209 LYS C O   1 
ATOM   604  C CB  . LYS A 1 206 ? 134.413 158.279 147.506 1.00 74.57  ?  209 LYS C CB  1 
ATOM   605  C CG  . LYS A 1 206 ? 135.246 158.384 148.769 1.00 74.57  ?  209 LYS C CG  1 
ATOM   606  C CD  . LYS A 1 206 ? 136.321 159.449 148.624 1.00 74.57  ?  209 LYS C CD  1 
ATOM   607  C CE  . LYS A 1 206 ? 137.178 159.546 149.874 1.00 74.57  ?  209 LYS C CE  1 
ATOM   608  N NZ  . LYS A 1 206 ? 138.019 158.333 150.064 1.00 74.57  1  209 LYS C NZ  1 
ATOM   609  N N   . LYS A 1 207 ? 133.401 155.558 149.353 1.00 68.14  ?  210 LYS C N   1 
ATOM   610  C CA  . LYS A 1 207 ? 133.854 154.311 149.952 1.00 68.14  ?  210 LYS C CA  1 
ATOM   611  C C   . LYS A 1 207 ? 133.000 153.112 149.565 1.00 68.14  ?  210 LYS C C   1 
ATOM   612  O O   . LYS A 1 207 ? 133.409 151.975 149.823 1.00 68.14  ?  210 LYS C O   1 
ATOM   613  C CB  . LYS A 1 207 ? 133.888 154.441 151.478 1.00 68.14  ?  210 LYS C CB  1 
ATOM   614  C CG  . LYS A 1 207 ? 135.191 155.003 152.015 1.00 68.14  ?  210 LYS C CG  1 
ATOM   615  C CD  . LYS A 1 207 ? 136.377 154.209 151.498 1.00 68.14  ?  210 LYS C CD  1 
ATOM   616  C CE  . LYS A 1 207 ? 137.691 154.879 151.850 1.00 68.14  ?  210 LYS C CE  1 
ATOM   617  N NZ  . LYS A 1 207 ? 138.849 154.171 151.240 1.00 68.14  1  210 LYS C NZ  1 
ATOM   618  N N   . TRP A 1 208 ? 131.833 153.330 148.958 1.00 66.81  ?  211 TRP C N   1 
ATOM   619  C CA  . TRP A 1 208 ? 130.980 152.226 148.544 1.00 66.81  ?  211 TRP C CA  1 
ATOM   620  C C   . TRP A 1 208 ? 130.361 152.410 147.166 1.00 66.81  ?  211 TRP C C   1 
ATOM   621  O O   . TRP A 1 208 ? 129.629 151.521 146.721 1.00 66.81  ?  211 TRP C O   1 
ATOM   622  C CB  . TRP A 1 208 ? 129.859 151.998 149.573 1.00 66.81  ?  211 TRP C CB  1 
ATOM   623  C CG  . TRP A 1 208 ? 129.092 153.236 149.926 1.00 66.81  ?  211 TRP C CG  1 
ATOM   624  C CD1 . TRP A 1 208 ? 129.252 154.004 151.040 1.00 66.81  ?  211 TRP C CD1 1 
ATOM   625  C CD2 . TRP A 1 208 ? 128.038 153.843 149.168 1.00 66.81  ?  211 TRP C CD2 1 
ATOM   626  N NE1 . TRP A 1 208 ? 128.369 155.055 151.021 1.00 66.81  ?  211 TRP C NE1 1 
ATOM   627  C CE2 . TRP A 1 208 ? 127.612 154.979 149.882 1.00 66.81  ?  211 TRP C CE2 1 
ATOM   628  C CE3 . TRP A 1 208 ? 127.416 153.539 147.954 1.00 66.81  ?  211 TRP C CE3 1 
ATOM   629  C CZ2 . TRP A 1 208 ? 126.594 155.810 149.424 1.00 66.81  ?  211 TRP C CZ2 1 
ATOM   630  C CZ3 . TRP A 1 208 ? 126.407 154.366 147.501 1.00 66.81  ?  211 TRP C CZ3 1 
ATOM   631  C CH2 . TRP A 1 208 ? 126.006 155.487 148.234 1.00 66.81  ?  211 TRP C CH2 1 
ATOM   632  N N   . ILE A 1 209 ? 130.618 153.526 146.481 1.00 66.24  ?  212 ILE C N   1 
ATOM   633  C CA  . ILE A 1 209 ? 130.004 153.745 145.176 1.00 66.24  ?  212 ILE C CA  1 
ATOM   634  C C   . ILE A 1 209 ? 130.538 152.754 144.149 1.00 66.24  ?  212 ILE C C   1 
ATOM   635  O O   . ILE A 1 209 ? 129.818 152.363 143.221 1.00 66.24  ?  212 ILE C O   1 
ATOM   636  C CB  . ILE A 1 209 ? 130.203 155.208 144.730 1.00 66.24  ?  212 ILE C CB  1 
ATOM   637  C CG1 . ILE A 1 209 ? 129.150 155.598 143.693 1.00 66.24  ?  212 ILE C CG1 1 
ATOM   638  C CG2 . ILE A 1 209 ? 131.608 155.438 144.194 1.00 66.24  ?  212 ILE C CG2 1 
ATOM   639  C CD1 . ILE A 1 209 ? 127.751 155.698 144.253 1.00 66.24  ?  212 ILE C CD1 1 
ATOM   640  N N   . HIS A 1 210 ? 131.783 152.299 144.311 1.00 64.38  ?  213 HIS C N   1 
ATOM   641  C CA  . HIS A 1 210 ? 132.367 151.353 143.370 1.00 64.38  ?  213 HIS C CA  1 
ATOM   642  C C   . HIS A 1 210 ? 131.654 150.010 143.374 1.00 64.38  ?  213 HIS C C   1 
ATOM   643  O O   . HIS A 1 210 ? 131.878 149.207 142.463 1.00 64.38  ?  213 HIS C O   1 
ATOM   644  C CB  . HIS A 1 210 ? 133.852 151.153 143.674 1.00 64.38  ?  213 HIS C CB  1 
ATOM   645  C CG  . HIS A 1 210 ? 134.138 150.809 145.102 1.00 64.38  ?  213 HIS C CG  1 
ATOM   646  N ND1 . HIS A 1 210 ? 133.807 149.592 145.655 1.00 64.38  ?  213 HIS C ND1 1 
ATOM   647  C CD2 . HIS A 1 210 ? 134.728 151.523 146.089 1.00 64.38  ?  213 HIS C CD2 1 
ATOM   648  C CE1 . HIS A 1 210 ? 134.178 149.571 146.923 1.00 64.38  ?  213 HIS C CE1 1 
ATOM   649  N NE2 . HIS A 1 210 ? 134.739 150.731 147.211 1.00 64.38  ?  213 HIS C NE2 1 
ATOM   650  N N   . CYS A 1 211 ? 130.813 149.747 144.376 1.00 64.57  ?  214 CYS C N   1 
ATOM   651  C CA  . CYS A 1 211 ? 129.981 148.551 144.345 1.00 64.57  ?  214 CYS C CA  1 
ATOM   652  C C   . CYS A 1 211 ? 129.017 148.589 143.167 1.00 64.57  ?  214 CYS C C   1 
ATOM   653  O O   . CYS A 1 211 ? 128.743 147.556 142.546 1.00 64.57  ?  214 CYS C O   1 
ATOM   654  C CB  . CYS A 1 211 ? 129.217 148.408 145.660 1.00 64.57  ?  214 CYS C CB  1 
ATOM   655  S SG  . CYS A 1 211 ? 130.265 148.335 147.129 1.00 64.57  ?  214 CYS C SG  1 
ATOM   656  N N   . PHE A 1 212 ? 128.494 149.769 142.844 1.00 60.63  ?  215 PHE C N   1 
ATOM   657  C CA  . PHE A 1 212 ? 127.561 149.913 141.727 1.00 60.63  ?  215 PHE C CA  1 
ATOM   658  C C   . PHE A 1 212 ? 128.290 150.246 140.429 1.00 60.63  ?  215 PHE C C   1 
ATOM   659  O O   . PHE A 1 212 ? 127.940 151.188 139.724 1.00 60.63  ?  215 PHE C O   1 
ATOM   660  C CB  . PHE A 1 212 ? 126.521 150.978 142.052 1.00 60.63  ?  215 PHE C CB  1 
ATOM   661  C CG  . PHE A 1 212 ? 125.776 150.731 143.330 1.00 60.63  ?  215 PHE C CG  1 
ATOM   662  C CD1 . PHE A 1 212 ? 124.636 149.951 143.342 1.00 60.63  ?  215 PHE C CD1 1 
ATOM   663  C CD2 . PHE A 1 212 ? 126.211 151.290 144.518 1.00 60.63  ?  215 PHE C CD2 1 
ATOM   664  C CE1 . PHE A 1 212 ? 123.947 149.726 144.515 1.00 60.63  ?  215 PHE C CE1 1 
ATOM   665  C CE2 . PHE A 1 212 ? 125.527 151.068 145.694 1.00 60.63  ?  215 PHE C CE2 1 
ATOM   666  C CZ  . PHE A 1 212 ? 124.393 150.286 145.692 1.00 60.63  ?  215 PHE C CZ  1 
ATOM   667  N N   . GLU A 1 213 ? 129.311 149.457 140.096 1.00 64.82  ?  216 GLU C N   1 
ATOM   668  C CA  . GLU A 1 213 ? 130.081 149.726 138.888 1.00 64.82  ?  216 GLU C CA  1 
ATOM   669  C C   . GLU A 1 213 ? 129.454 149.089 137.656 1.00 64.82  ?  216 GLU C C   1 
ATOM   670  O O   . GLU A 1 213 ? 129.615 149.608 136.546 1.00 64.82  ?  216 GLU C O   1 
ATOM   671  C CB  . GLU A 1 213 ? 131.518 149.235 139.059 1.00 64.82  ?  216 GLU C CB  1 
ATOM   672  C CG  . GLU A 1 213 ? 132.491 149.803 138.042 1.00 64.82  ?  216 GLU C CG  1 
ATOM   673  C CD  . GLU A 1 213 ? 133.883 149.225 138.182 1.00 64.82  ?  216 GLU C CD  1 
ATOM   674  O OE1 . GLU A 1 213 ? 134.079 148.346 139.046 1.00 64.82  ?  216 GLU C OE1 1 
ATOM   675  O OE2 . GLU A 1 213 ? 134.783 149.650 137.427 1.00 64.82  -1 216 GLU C OE2 1 
ATOM   676  N N   . GLY A 1 214 ? 128.742 147.979 137.826 1.00 64.87  ?  217 GLY C N   1 
ATOM   677  C CA  . GLY A 1 214 ? 128.129 147.268 136.726 1.00 64.87  ?  217 GLY C CA  1 
ATOM   678  C C   . GLY A 1 214 ? 126.665 147.566 136.488 1.00 64.87  ?  217 GLY C C   1 
ATOM   679  O O   . GLY A 1 214 ? 126.018 146.826 135.737 1.00 64.87  ?  217 GLY C O   1 
ATOM   680  N N   . VAL A 1 215 ? 126.116 148.614 137.102 1.00 60.88  ?  218 VAL C N   1 
ATOM   681  C CA  . VAL A 1 215 ? 124.718 148.959 136.881 1.00 60.88  ?  218 VAL C CA  1 
ATOM   682  C C   . VAL A 1 215 ? 124.523 149.394 135.437 1.00 60.88  ?  218 VAL C C   1 
ATOM   683  O O   . VAL A 1 215 ? 125.386 150.055 134.843 1.00 60.88  ?  218 VAL C O   1 
ATOM   684  C CB  . VAL A 1 215 ? 124.267 150.056 137.860 1.00 60.88  ?  218 VAL C CB  1 
ATOM   685  C CG1 . VAL A 1 215 ? 124.130 149.489 139.261 1.00 60.88  ?  218 VAL C CG1 1 
ATOM   686  C CG2 . VAL A 1 215 ? 125.243 151.218 137.843 1.00 60.88  ?  218 VAL C CG2 1 
ATOM   687  N N   . THR A 1 216 ? 123.386 149.010 134.856 1.00 62.43  ?  219 THR C N   1 
ATOM   688  C CA  . THR A 1 216 ? 123.118 149.365 133.467 1.00 62.43  ?  219 THR C CA  1 
ATOM   689  C C   . THR A 1 216 ? 122.888 150.862 133.312 1.00 62.43  ?  219 THR C C   1 
ATOM   690  O O   . THR A 1 216 ? 123.290 151.455 132.304 1.00 62.43  ?  219 THR C O   1 
ATOM   691  C CB  . THR A 1 216 ? 121.913 148.585 132.944 1.00 62.43  ?  219 THR C CB  1 
ATOM   692  O OG1 . THR A 1 216 ? 120.711 149.159 133.466 1.00 62.43  ?  219 THR C OG1 1 
ATOM   693  C CG2 . THR A 1 216 ? 122.000 147.130 133.368 1.00 62.43  ?  219 THR C CG2 1 
ATOM   694  N N   . ALA A 1 217 ? 122.246 151.493 134.293 1.00 59.11  ?  220 ALA C N   1 
ATOM   695  C CA  . ALA A 1 217 ? 121.955 152.914 134.196 1.00 59.11  ?  220 ALA C CA  1 
ATOM   696  C C   . ALA A 1 217 ? 121.816 153.518 135.585 1.00 59.11  ?  220 ALA C C   1 
ATOM   697  O O   . ALA A 1 217 ? 121.569 152.822 136.577 1.00 59.11  ?  220 ALA C O   1 
ATOM   698  C CB  . ALA A 1 217 ? 120.684 153.171 133.378 1.00 59.11  ?  220 ALA C CB  1 
ATOM   699  N N   . ILE A 1 218 ? 121.974 154.837 135.637 1.00 58.07  ?  221 ILE C N   1 
ATOM   700  C CA  . ILE A 1 218 ? 121.797 155.614 136.856 1.00 58.07  ?  221 ILE C CA  1 
ATOM   701  C C   . ILE A 1 218 ? 120.607 156.537 136.647 1.00 58.07  ?  221 ILE C C   1 
ATOM   702  O O   . ILE A 1 218 ? 120.655 157.442 135.807 1.00 58.07  ?  221 ILE C O   1 
ATOM   703  C CB  . ILE A 1 218 ? 123.060 156.415 137.206 1.00 58.07  ?  221 ILE C CB  1 
ATOM   704  C CG1 . ILE A 1 218 ? 124.189 155.476 137.628 1.00 58.07  ?  221 ILE C CG1 1 
ATOM   705  C CG2 . ILE A 1 218 ? 122.765 157.421 138.303 1.00 58.07  ?  221 ILE C CG2 1 
ATOM   706  C CD1 . ILE A 1 218 ? 125.550 156.123 137.600 1.00 58.07  ?  221 ILE C CD1 1 
ATOM   707  N N   . ILE A 1 219 ? 119.540 156.310 137.404 1.00 58.93  ?  222 ILE C N   1 
ATOM   708  C CA  . ILE A 1 219 ? 118.347 157.144 137.337 1.00 58.93  ?  222 ILE C CA  1 
ATOM   709  C C   . ILE A 1 219 ? 118.536 158.292 138.320 1.00 58.93  ?  222 ILE C C   1 
ATOM   710  O O   . ILE A 1 219 ? 118.424 158.107 139.533 1.00 58.93  ?  222 ILE C O   1 
ATOM   711  C CB  . ILE A 1 219 ? 117.079 156.344 137.653 1.00 58.93  ?  222 ILE C CB  1 
ATOM   712  C CG1 . ILE A 1 219 ? 116.862 155.254 136.603 1.00 58.93  ?  222 ILE C CG1 1 
ATOM   713  C CG2 . ILE A 1 219 ? 115.874 157.263 137.717 1.00 58.93  ?  222 ILE C CG2 1 
ATOM   714  C CD1 . ILE A 1 219 ? 115.550 154.522 136.753 1.00 58.93  ?  222 ILE C CD1 1 
ATOM   715  N N   . PHE A 1 220 ? 118.828 159.478 137.799 1.00 68.17  ?  223 PHE C N   1 
ATOM   716  C CA  . PHE A 1 220 ? 119.073 160.655 138.621 1.00 68.17  ?  223 PHE C CA  1 
ATOM   717  C C   . PHE A 1 220 ? 117.824 161.525 138.621 1.00 68.17  ?  223 PHE C C   1 
ATOM   718  O O   . PHE A 1 220 ? 117.401 162.006 137.565 1.00 68.17  ?  223 PHE C O   1 
ATOM   719  C CB  . PHE A 1 220 ? 120.279 161.437 138.102 1.00 68.17  ?  223 PHE C CB  1 
ATOM   720  C CG  . PHE A 1 220 ? 120.937 162.293 139.142 1.00 68.17  ?  223 PHE C CG  1 
ATOM   721  C CD1 . PHE A 1 220 ? 120.423 163.536 139.462 1.00 68.17  ?  223 PHE C CD1 1 
ATOM   722  C CD2 . PHE A 1 220 ? 122.070 161.852 139.802 1.00 68.17  ?  223 PHE C CD2 1 
ATOM   723  C CE1 . PHE A 1 220 ? 121.025 164.323 140.419 1.00 68.17  ?  223 PHE C CE1 1 
ATOM   724  C CE2 . PHE A 1 220 ? 122.676 162.636 140.760 1.00 68.17  ?  223 PHE C CE2 1 
ATOM   725  C CZ  . PHE A 1 220 ? 122.153 163.873 141.069 1.00 68.17  ?  223 PHE C CZ  1 
ATOM   726  N N   . CYS A 1 221 ? 117.246 161.734 139.799 1.00 76.60  ?  224 CYS C N   1 
ATOM   727  C CA  . CYS A 1 221 ? 116.015 162.499 139.942 1.00 76.60  ?  224 CYS C CA  1 
ATOM   728  C C   . CYS A 1 221 ? 116.331 163.895 140.459 1.00 76.60  ?  224 CYS C C   1 
ATOM   729  O O   . CYS A 1 221 ? 116.995 164.044 141.490 1.00 76.60  ?  224 CYS C O   1 
ATOM   730  C CB  . CYS A 1 221 ? 115.044 161.794 140.889 1.00 76.60  ?  224 CYS C CB  1 
ATOM   731  S SG  . CYS A 1 221 ? 114.397 160.228 140.265 1.00 76.60  ?  224 CYS C SG  1 
ATOM   732  N N   . VAL A 1 222 ? 115.855 164.912 139.744 1.00 81.33  ?  225 VAL C N   1 
ATOM   733  C CA  . VAL A 1 222 ? 116.038 166.306 140.129 1.00 81.33  ?  225 VAL C CA  1 
ATOM   734  C C   . VAL A 1 222 ? 114.676 166.982 140.117 1.00 81.33  ?  225 VAL C C   1 
ATOM   735  O O   . VAL A 1 222 ? 113.937 166.876 139.134 1.00 81.33  ?  225 VAL C O   1 
ATOM   736  C CB  . VAL A 1 222 ? 117.012 167.037 139.187 1.00 81.33  ?  225 VAL C CB  1 
ATOM   737  C CG1 . VAL A 1 222 ? 116.970 168.533 139.440 1.00 81.33  ?  225 VAL C CG1 1 
ATOM   738  C CG2 . VAL A 1 222 ? 118.419 166.504 139.364 1.00 81.33  ?  225 VAL C CG2 1 
ATOM   739  N N   . ALA A 1 223 ? 114.345 167.674 141.202 1.00 91.03  ?  226 ALA C N   1 
ATOM   740  C CA  . ALA A 1 223 ? 113.072 168.375 141.309 1.00 91.03  ?  226 ALA C CA  1 
ATOM   741  C C   . ALA A 1 223 ? 113.210 169.763 140.697 1.00 91.03  ?  226 ALA C C   1 
ATOM   742  O O   . ALA A 1 223 ? 114.043 170.561 141.139 1.00 91.03  ?  226 ALA C O   1 
ATOM   743  C CB  . ALA A 1 223 ? 112.628 168.471 142.768 1.00 91.03  ?  226 ALA C CB  1 
ATOM   744  N N   . LEU A 1 224 ? 112.395 170.050 139.679 1.00 95.88  ?  227 LEU C N   1 
ATOM   745  C CA  . LEU A 1 224 ? 112.448 171.358 139.037 1.00 95.88  ?  227 LEU C CA  1 
ATOM   746  C C   . LEU A 1 224 ? 111.917 172.466 139.935 1.00 95.88  ?  227 LEU C C   1 
ATOM   747  O O   . LEU A 1 224 ? 112.219 173.639 139.694 1.00 95.88  ?  227 LEU C O   1 
ATOM   748  C CB  . LEU A 1 224 ? 111.659 171.340 137.727 1.00 95.88  ?  227 LEU C CB  1 
ATOM   749  C CG  . LEU A 1 224 ? 112.191 170.444 136.610 1.00 95.88  ?  227 LEU C CG  1 
ATOM   750  C CD1 . LEU A 1 224 ? 111.172 170.331 135.489 1.00 95.88  ?  227 LEU C CD1 1 
ATOM   751  C CD2 . LEU A 1 224 ? 113.509 170.980 136.085 1.00 95.88  ?  227 LEU C CD2 1 
ATOM   752  N N   . SER A 1 225 ? 111.143 172.121 140.960 1.00 104.29 ?  228 SER C N   1 
ATOM   753  C CA  . SER A 1 225 ? 110.577 173.104 141.873 1.00 104.29 ?  228 SER C CA  1 
ATOM   754  C C   . SER A 1 225 ? 111.540 173.516 142.977 1.00 104.29 ?  228 SER C C   1 
ATOM   755  O O   . SER A 1 225 ? 111.191 174.381 143.787 1.00 104.29 ?  228 SER C O   1 
ATOM   756  C CB  . SER A 1 225 ? 109.289 172.554 142.490 1.00 104.29 ?  228 SER C CB  1 
ATOM   757  O OG  . SER A 1 225 ? 109.570 171.532 143.429 1.00 104.29 ?  228 SER C OG  1 
ATOM   758  N N   . ASP A 1 226 ? 112.730 172.926 143.031 1.00 105.81 ?  229 ASP C N   1 
ATOM   759  C CA  . ASP A 1 226 ? 113.721 173.256 144.043 1.00 105.81 ?  229 ASP C CA  1 
ATOM   760  C C   . ASP A 1 226 ? 114.704 174.322 143.577 1.00 105.81 ?  229 ASP C C   1 
ATOM   761  O O   . ASP A 1 226 ? 115.691 174.583 144.271 1.00 105.81 ?  229 ASP C O   1 
ATOM   762  C CB  . ASP A 1 226 ? 114.483 171.996 144.465 1.00 105.81 ?  229 ASP C CB  1 
ATOM   763  N N   . TYR A 1 227 ? 114.457 174.938 142.419 1.00 109.28 ?  230 TYR C N   1 
ATOM   764  C CA  . TYR A 1 227 ? 115.374 175.945 141.899 1.00 109.28 ?  230 TYR C CA  1 
ATOM   765  C C   . TYR A 1 227 ? 115.392 177.212 142.743 1.00 109.28 ?  230 TYR C C   1 
ATOM   766  O O   . TYR A 1 227 ? 116.429 177.881 142.806 1.00 109.28 ?  230 TYR C O   1 
ATOM   767  C CB  . TYR A 1 227 ? 115.015 176.279 140.449 1.00 109.28 ?  230 TYR C CB  1 
ATOM   768  C CG  . TYR A 1 227 ? 113.876 177.262 140.295 1.00 109.28 ?  230 TYR C CG  1 
ATOM   769  C CD1 . TYR A 1 227 ? 112.557 176.851 140.414 1.00 109.28 ?  230 TYR C CD1 1 
ATOM   770  C CD2 . TYR A 1 227 ? 114.122 178.600 140.018 1.00 109.28 ?  230 TYR C CD2 1 
ATOM   771  C CE1 . TYR A 1 227 ? 111.514 177.745 140.269 1.00 109.28 ?  230 TYR C CE1 1 
ATOM   772  C CE2 . TYR A 1 227 ? 113.087 179.501 139.872 1.00 109.28 ?  230 TYR C CE2 1 
ATOM   773  C CZ  . TYR A 1 227 ? 111.785 179.069 139.998 1.00 109.28 ?  230 TYR C CZ  1 
ATOM   774  O OH  . TYR A 1 227 ? 110.752 179.965 139.853 1.00 109.28 ?  230 TYR C OH  1 
ATOM   775  N N   . ASP A 1 228 ? 114.283 177.555 143.395 1.00 109.90 ?  231 ASP C N   1 
ATOM   776  C CA  . ASP A 1 228 ? 114.199 178.759 144.212 1.00 109.90 ?  231 ASP C CA  1 
ATOM   777  C C   . ASP A 1 228 ? 114.021 178.425 145.690 1.00 109.90 ?  231 ASP C C   1 
ATOM   778  O O   . ASP A 1 228 ? 113.300 179.120 146.409 1.00 109.90 ?  231 ASP C O   1 
ATOM   779  C CB  . ASP A 1 228 ? 113.071 179.667 143.723 1.00 109.90 ?  231 ASP C CB  1 
ATOM   780  C CG  . ASP A 1 228 ? 111.717 178.981 143.732 1.00 109.90 ?  231 ASP C CG  1 
ATOM   781  O OD1 . ASP A 1 228 ? 111.655 177.771 144.036 1.00 109.90 ?  231 ASP C OD1 1 
ATOM   782  O OD2 . ASP A 1 228 ? 110.710 179.657 143.436 1.00 109.90 -1 231 ASP C OD2 1 
ATOM   783  N N   . LEU A 1 229 ? 114.674 177.364 146.155 1.00 107.94 ?  232 LEU C N   1 
ATOM   784  C CA  . LEU A 1 229 ? 114.611 176.953 147.548 1.00 107.94 ?  232 LEU C CA  1 
ATOM   785  C C   . LEU A 1 229 ? 116.020 176.728 148.076 1.00 107.94 ?  232 LEU C C   1 
ATOM   786  O O   . LEU A 1 229 ? 116.954 176.451 147.319 1.00 107.94 ?  232 LEU C O   1 
ATOM   787  C CB  . LEU A 1 229 ? 113.770 175.680 147.724 1.00 107.94 ?  232 LEU C CB  1 
ATOM   788  N N   . VAL A 1 230 ? 116.164 176.851 149.392 1.00 105.07 ?  233 VAL C N   1 
ATOM   789  C CA  . VAL A 1 230 ? 117.457 176.670 150.039 1.00 105.07 ?  233 VAL C CA  1 
ATOM   790  C C   . VAL A 1 230 ? 117.401 175.510 151.024 1.00 105.07 ?  233 VAL C C   1 
ATOM   791  O O   . VAL A 1 230 ? 118.435 175.019 151.479 1.00 105.07 ?  233 VAL C O   1 
ATOM   792  C CB  . VAL A 1 230 ? 117.909 177.959 150.745 1.00 105.07 ?  233 VAL C CB  1 
ATOM   793  N N   . ASN A 1 238 ? 119.414 177.372 145.355 1.00 107.84 ?  241 ASN C N   1 
ATOM   794  C CA  . ASN A 1 238 ? 120.455 176.749 146.164 1.00 107.84 ?  241 ASN C CA  1 
ATOM   795  C C   . ASN A 1 238 ? 120.363 175.229 146.099 1.00 107.84 ?  241 ASN C C   1 
ATOM   796  O O   . ASN A 1 238 ? 121.360 174.549 145.856 1.00 107.84 ?  241 ASN C O   1 
ATOM   797  C CB  . ASN A 1 238 ? 120.361 177.221 147.616 1.00 107.84 ?  241 ASN C CB  1 
ATOM   798  C CG  . ASN A 1 238 ? 121.582 176.841 148.432 1.00 107.84 ?  241 ASN C CG  1 
ATOM   799  O OD1 . ASN A 1 238 ? 121.466 176.245 149.503 1.00 107.84 ?  241 ASN C OD1 1 
ATOM   800  N ND2 . ASN A 1 238 ? 122.761 177.186 147.928 1.00 107.84 ?  241 ASN C ND2 1 
ATOM   801  N N   . ARG A 1 239 ? 119.157 174.701 146.324 1.00 105.16 ?  242 ARG C N   1 
ATOM   802  C CA  . ARG A 1 239 ? 118.961 173.257 146.258 1.00 105.16 ?  242 ARG C CA  1 
ATOM   803  C C   . ARG A 1 239 ? 119.179 172.730 144.847 1.00 105.16 ?  242 ARG C C   1 
ATOM   804  O O   . ARG A 1 239 ? 119.695 171.619 144.670 1.00 105.16 ?  242 ARG C O   1 
ATOM   805  C CB  . ARG A 1 239 ? 117.564 172.897 146.762 1.00 105.16 ?  242 ARG C CB  1 
ATOM   806  C CG  . ARG A 1 239 ? 117.365 173.180 148.243 1.00 105.16 ?  242 ARG C CG  1 
ATOM   807  C CD  . ARG A 1 239 ? 115.961 172.833 148.704 1.00 105.16 ?  242 ARG C CD  1 
ATOM   808  N NE  . ARG A 1 239 ? 115.701 171.400 148.640 1.00 105.16 ?  242 ARG C NE  1 
ATOM   809  C CZ  . ARG A 1 239 ? 114.512 170.846 148.832 1.00 105.16 ?  242 ARG C CZ  1 
ATOM   810  N NH1 . ARG A 1 239 ? 113.445 171.578 149.107 1.00 105.16 1  242 ARG C NH1 1 
ATOM   811  N NH2 . ARG A 1 239 ? 114.391 169.525 148.746 1.00 105.16 ?  242 ARG C NH2 1 
ATOM   812  N N   . MET A 1 240 ? 118.796 173.508 143.832 1.00 102.13 ?  243 MET C N   1 
ATOM   813  C CA  . MET A 1 240 ? 119.109 173.132 142.458 1.00 102.13 ?  243 MET C CA  1 
ATOM   814  C C   . MET A 1 240 ? 120.615 173.094 142.236 1.00 102.13 ?  243 MET C C   1 
ATOM   815  O O   . MET A 1 240 ? 121.121 172.232 141.510 1.00 102.13 ?  243 MET C O   1 
ATOM   816  C CB  . MET A 1 240 ? 118.445 174.101 141.481 1.00 102.13 ?  243 MET C CB  1 
ATOM   817  C CG  . MET A 1 240 ? 118.701 173.783 140.018 1.00 102.13 ?  243 MET C CG  1 
ATOM   818  S SD  . MET A 1 240 ? 117.862 172.285 139.471 1.00 102.13 ?  243 MET C SD  1 
ATOM   819  C CE  . MET A 1 240 ? 116.191 172.893 139.264 1.00 102.13 ?  243 MET C CE  1 
ATOM   820  N N   . HIS A 1 241 ? 121.349 174.020 142.856 1.00 102.77 ?  244 HIS C N   1 
ATOM   821  C CA  . HIS A 1 241 ? 122.804 173.986 142.766 1.00 102.77 ?  244 HIS C CA  1 
ATOM   822  C C   . HIS A 1 241 ? 123.371 172.752 143.458 1.00 102.77 ?  244 HIS C C   1 
ATOM   823  O O   . HIS A 1 241 ? 124.352 172.166 142.986 1.00 102.77 ?  244 HIS C O   1 
ATOM   824  C CB  . HIS A 1 241 ? 123.397 175.262 143.360 1.00 102.77 ?  244 HIS C CB  1 
ATOM   825  C CG  . HIS A 1 241 ? 123.224 176.467 142.490 1.00 102.77 ?  244 HIS C CG  1 
ATOM   826  N ND1 . HIS A 1 241 ? 124.045 176.733 141.416 1.00 102.77 ?  244 HIS C ND1 1 
ATOM   827  C CD2 . HIS A 1 241 ? 122.321 177.475 142.532 1.00 102.77 ?  244 HIS C CD2 1 
ATOM   828  C CE1 . HIS A 1 241 ? 123.657 177.854 140.835 1.00 102.77 ?  244 HIS C CE1 1 
ATOM   829  N NE2 . HIS A 1 241 ? 122.613 178.325 141.493 1.00 102.77 ?  244 HIS C NE2 1 
ATOM   830  N N   . GLU A 1 242 ? 122.771 172.343 144.578 1.00 98.92  ?  245 GLU C N   1 
ATOM   831  C CA  . GLU A 1 242 ? 123.192 171.108 145.233 1.00 98.92  ?  245 GLU C CA  1 
ATOM   832  C C   . GLU A 1 242 ? 122.953 169.901 144.333 1.00 98.92  ?  245 GLU C C   1 
ATOM   833  O O   . GLU A 1 242 ? 123.804 169.008 144.234 1.00 98.92  ?  245 GLU C O   1 
ATOM   834  C CB  . GLU A 1 242 ? 122.455 170.943 146.561 1.00 98.92  ?  245 GLU C CB  1 
ATOM   835  C CG  . GLU A 1 242 ? 122.947 169.782 147.409 1.00 98.92  ?  245 GLU C CG  1 
ATOM   836  C CD  . GLU A 1 242 ? 124.263 170.081 148.098 1.00 98.92  ?  245 GLU C CD  1 
ATOM   837  O OE1 . GLU A 1 242 ? 124.566 171.274 148.311 1.00 98.92  ?  245 GLU C OE1 1 
ATOM   838  O OE2 . GLU A 1 242 ? 124.994 169.124 148.428 1.00 98.92  -1 245 GLU C OE2 1 
ATOM   839  N N   . SER A 1 243 ? 121.796 169.860 143.667 1.00 92.31  ?  246 SER C N   1 
ATOM   840  C CA  . SER A 1 243 ? 121.518 168.776 142.732 1.00 92.31  ?  246 SER C CA  1 
ATOM   841  C C   . SER A 1 243 ? 122.505 168.786 141.572 1.00 92.31  ?  246 SER C C   1 
ATOM   842  O O   . SER A 1 243 ? 122.952 167.727 141.118 1.00 92.31  ?  246 SER C O   1 
ATOM   843  C CB  . SER A 1 243 ? 120.083 168.881 142.216 1.00 92.31  ?  246 SER C CB  1 
ATOM   844  O OG  . SER A 1 243 ? 119.151 168.755 143.275 1.00 92.31  ?  246 SER C OG  1 
ATOM   845  N N   . MET A 1 244 ? 122.850 169.976 141.075 1.00 92.57  ?  247 MET C N   1 
ATOM   846  C CA  . MET A 1 244 ? 123.824 170.078 139.994 1.00 92.57  ?  247 MET C CA  1 
ATOM   847  C C   . MET A 1 244 ? 125.194 169.584 140.438 1.00 92.57  ?  247 MET C C   1 
ATOM   848  O O   . MET A 1 244 ? 125.889 168.900 139.680 1.00 92.57  ?  247 MET C O   1 
ATOM   849  C CB  . MET A 1 244 ? 123.909 171.522 139.500 1.00 92.57  ?  247 MET C CB  1 
ATOM   850  C CG  . MET A 1 244 ? 122.766 171.935 138.590 1.00 92.57  ?  247 MET C CG  1 
ATOM   851  S SD  . MET A 1 244 ? 123.033 173.540 137.814 1.00 92.57  ?  247 MET C SD  1 
ATOM   852  C CE  . MET A 1 244 ? 124.816 173.541 137.640 1.00 92.57  ?  247 MET C CE  1 
ATOM   853  N N   . LYS A 1 245 ? 125.603 169.928 141.661 1.00 89.75  ?  248 LYS C N   1 
ATOM   854  C CA  . LYS A 1 245 ? 126.878 169.442 142.182 1.00 89.75  ?  248 LYS C CA  1 
ATOM   855  C C   . LYS A 1 245 ? 126.875 167.924 142.314 1.00 89.75  ?  248 LYS C C   1 
ATOM   856  O O   . LYS A 1 245 ? 127.860 167.260 141.968 1.00 89.75  ?  248 LYS C O   1 
ATOM   857  C CB  . LYS A 1 245 ? 127.178 170.093 143.531 1.00 89.75  ?  248 LYS C CB  1 
ATOM   858  C CG  . LYS A 1 245 ? 127.564 171.559 143.449 1.00 89.75  ?  248 LYS C CG  1 
ATOM   859  C CD  . LYS A 1 245 ? 127.678 172.172 144.836 1.00 89.75  ?  248 LYS C CD  1 
ATOM   860  C CE  . LYS A 1 245 ? 127.809 173.683 144.766 1.00 89.75  ?  248 LYS C CE  1 
ATOM   861  N NZ  . LYS A 1 245 ? 127.773 174.305 146.118 1.00 89.75  1  248 LYS C NZ  1 
ATOM   862  N N   . LEU A 1 246 ? 125.775 167.359 142.816 1.00 82.34  ?  249 LEU C N   1 
ATOM   863  C CA  . LEU A 1 246 ? 125.684 165.907 142.936 1.00 82.34  ?  249 LEU C CA  1 
ATOM   864  C C   . LEU A 1 246 ? 125.733 165.237 141.568 1.00 82.34  ?  249 LEU C C   1 
ATOM   865  O O   . LEU A 1 246 ? 126.390 164.202 141.398 1.00 82.34  ?  249 LEU C O   1 
ATOM   866  C CB  . LEU A 1 246 ? 124.406 165.521 143.679 1.00 82.34  ?  249 LEU C CB  1 
ATOM   867  C CG  . LEU A 1 246 ? 124.237 164.040 144.026 1.00 82.34  ?  249 LEU C CG  1 
ATOM   868  C CD1 . LEU A 1 246 ? 125.539 163.448 144.540 1.00 82.34  ?  249 LEU C CD1 1 
ATOM   869  C CD2 . LEU A 1 246 ? 123.125 163.858 145.044 1.00 82.34  ?  249 LEU C CD2 1 
ATOM   870  N N   . PHE A 1 247 ? 125.042 165.811 140.581 1.00 80.11  ?  250 PHE C N   1 
ATOM   871  C CA  . PHE A 1 247 ? 125.071 165.253 139.233 1.00 80.11  ?  250 PHE C CA  1 
ATOM   872  C C   . PHE A 1 247 ? 126.466 165.343 138.631 1.00 80.11  ?  250 PHE C C   1 
ATOM   873  O O   . PHE A 1 247 ? 126.911 164.422 137.939 1.00 80.11  ?  250 PHE C O   1 
ATOM   874  C CB  . PHE A 1 247 ? 124.056 165.971 138.343 1.00 80.11  ?  250 PHE C CB  1 
ATOM   875  C CG  . PHE A 1 247 ? 123.893 165.347 136.987 1.00 80.11  ?  250 PHE C CG  1 
ATOM   876  C CD1 . PHE A 1 247 ? 122.973 164.335 136.783 1.00 80.11  ?  250 PHE C CD1 1 
ATOM   877  C CD2 . PHE A 1 247 ? 124.659 165.773 135.916 1.00 80.11  ?  250 PHE C CD2 1 
ATOM   878  C CE1 . PHE A 1 247 ? 122.822 163.758 135.540 1.00 80.11  ?  250 PHE C CE1 1 
ATOM   879  C CE2 . PHE A 1 247 ? 124.512 165.198 134.671 1.00 80.11  ?  250 PHE C CE2 1 
ATOM   880  C CZ  . PHE A 1 247 ? 123.592 164.191 134.482 1.00 80.11  ?  250 PHE C CZ  1 
ATOM   881  N N   . ASP A 1 248 ? 127.165 166.454 138.870 1.00 83.83  ?  251 ASP C N   1 
ATOM   882  C CA  . ASP A 1 248 ? 128.532 166.593 138.380 1.00 83.83  ?  251 ASP C CA  1 
ATOM   883  C C   . ASP A 1 248 ? 129.447 165.554 139.014 1.00 83.83  ?  251 ASP C C   1 
ATOM   884  O O   . ASP A 1 248 ? 130.298 164.967 138.336 1.00 83.83  ?  251 ASP C O   1 
ATOM   885  C CB  . ASP A 1 248 ? 129.042 168.007 138.662 1.00 83.83  ?  251 ASP C CB  1 
ATOM   886  C CG  . ASP A 1 248 ? 130.215 168.395 137.782 1.00 83.83  ?  251 ASP C CG  1 
ATOM   887  O OD1 . ASP A 1 248 ? 130.864 167.496 137.209 1.00 83.83  ?  251 ASP C OD1 1 
ATOM   888  O OD2 . ASP A 1 248 ? 130.488 169.608 137.662 1.00 83.83  -1 251 ASP C OD2 1 
ATOM   889  N N   . SER A 1 249 ? 129.287 165.316 140.317 1.00 81.00  ?  252 SER C N   1 
ATOM   890  C CA  . SER A 1 249 ? 130.114 164.321 140.991 1.00 81.00  ?  252 SER C CA  1 
ATOM   891  C C   . SER A 1 249 ? 129.817 162.912 140.489 1.00 81.00  ?  252 SER C C   1 
ATOM   892  O O   . SER A 1 249 ? 130.739 162.113 140.289 1.00 81.00  ?  252 SER C O   1 
ATOM   893  C CB  . SER A 1 249 ? 129.906 164.405 142.502 1.00 81.00  ?  252 SER C CB  1 
ATOM   894  O OG  . SER A 1 249 ? 130.312 163.206 143.138 1.00 81.00  ?  252 SER C OG  1 
ATOM   895  N N   . ILE A 1 250 ? 128.540 162.588 140.282 1.00 78.26  ?  253 ILE C N   1 
ATOM   896  C CA  . ILE A 1 250 ? 128.169 161.227 139.902 1.00 78.26  ?  253 ILE C CA  1 
ATOM   897  C C   . ILE A 1 250 ? 128.534 160.953 138.447 1.00 78.26  ?  253 ILE C C   1 
ATOM   898  O O   . ILE A 1 250 ? 129.122 159.915 138.123 1.00 78.26  ?  253 ILE C O   1 
ATOM   899  C CB  . ILE A 1 250 ? 126.671 160.990 140.164 1.00 78.26  ?  253 ILE C CB  1 
ATOM   900  C CG1 . ILE A 1 250 ? 126.415 160.810 141.660 1.00 78.26  ?  253 ILE C CG1 1 
ATOM   901  C CG2 . ILE A 1 250 ? 126.177 159.781 139.389 1.00 78.26  ?  253 ILE C CG2 1 
ATOM   902  C CD1 . ILE A 1 250 ? 127.155 159.640 142.267 1.00 78.26  ?  253 ILE C CD1 1 
ATOM   903  N N   . CYS A 1 251 ? 128.186 161.878 137.549 1.00 81.91  ?  254 CYS C N   1 
ATOM   904  C CA  . CYS A 1 251 ? 128.381 161.644 136.122 1.00 81.91  ?  254 CYS C CA  1 
ATOM   905  C C   . CYS A 1 251 ? 129.858 161.542 135.765 1.00 81.91  ?  254 CYS C C   1 
ATOM   906  O O   . CYS A 1 251 ? 130.252 160.690 134.960 1.00 81.91  ?  254 CYS C O   1 
ATOM   907  C CB  . CYS A 1 251 ? 127.713 162.758 135.318 1.00 81.91  ?  254 CYS C CB  1 
ATOM   908  S SG  . CYS A 1 251 ? 127.826 162.543 133.534 1.00 81.91  ?  254 CYS C SG  1 
ATOM   909  N N   . ASN A 1 252 ? 130.690 162.401 136.351 1.00 83.28  ?  255 ASN C N   1 
ATOM   910  C CA  . ASN A 1 252 ? 132.116 162.426 136.061 1.00 83.28  ?  255 ASN C CA  1 
ATOM   911  C C   . ASN A 1 252 ? 132.921 161.539 137.002 1.00 83.28  ?  255 ASN C C   1 
ATOM   912  O O   . ASN A 1 252 ? 134.148 161.674 137.069 1.00 83.28  ?  255 ASN C O   1 
ATOM   913  C CB  . ASN A 1 252 ? 132.637 163.863 136.114 1.00 83.28  ?  255 ASN C CB  1 
ATOM   914  C CG  . ASN A 1 252 ? 131.890 164.785 135.174 1.00 83.28  ?  255 ASN C CG  1 
ATOM   915  O OD1 . ASN A 1 252 ? 131.970 164.643 133.955 1.00 83.28  ?  255 ASN C OD1 1 
ATOM   916  N ND2 . ASN A 1 252 ? 131.155 165.735 135.737 1.00 83.28  ?  255 ASN C ND2 1 
ATOM   917  N N   . ASN A 1 253 ? 132.259 160.642 137.728 1.00 76.17  ?  256 ASN C N   1 
ATOM   918  C CA  . ASN A 1 253 ? 132.965 159.720 138.604 1.00 76.17  ?  256 ASN C CA  1 
ATOM   919  C C   . ASN A 1 253 ? 133.826 158.764 137.787 1.00 76.17  ?  256 ASN C C   1 
ATOM   920  O O   . ASN A 1 253 ? 133.516 158.441 136.637 1.00 76.17  ?  256 ASN C O   1 
ATOM   921  C CB  . ASN A 1 253 ? 131.971 158.934 139.459 1.00 76.17  ?  256 ASN C CB  1 
ATOM   922  C CG  . ASN A 1 253 ? 132.564 158.485 140.775 1.00 76.17  ?  256 ASN C CG  1 
ATOM   923  O OD1 . ASN A 1 253 ? 133.535 157.731 140.806 1.00 76.17  ?  256 ASN C OD1 1 
ATOM   924  N ND2 . ASN A 1 253 ? 131.980 158.945 141.875 1.00 76.17  ?  256 ASN C ND2 1 
ATOM   925  N N   . LYS A 1 254 ? 134.925 158.314 138.394 1.00 72.38  ?  257 LYS C N   1 
ATOM   926  C CA  . LYS A 1 254 ? 135.841 157.414 137.703 1.00 72.38  ?  257 LYS C CA  1 
ATOM   927  C C   . LYS A 1 254 ? 135.237 156.038 137.462 1.00 72.38  ?  257 LYS C C   1 
ATOM   928  O O   . LYS A 1 254 ? 135.754 155.286 136.630 1.00 72.38  ?  257 LYS C O   1 
ATOM   929  C CB  . LYS A 1 254 ? 137.142 157.279 138.495 1.00 72.38  ?  257 LYS C CB  1 
ATOM   930  C CG  . LYS A 1 254 ? 136.941 156.961 139.966 1.00 72.38  ?  257 LYS C CG  1 
ATOM   931  C CD  . LYS A 1 254 ? 138.268 156.723 140.664 1.00 72.38  ?  257 LYS C CD  1 
ATOM   932  C CE  . LYS A 1 254 ? 138.873 155.393 140.252 1.00 72.38  ?  257 LYS C CE  1 
ATOM   933  N NZ  . LYS A 1 254 ? 140.072 155.054 141.066 1.00 72.38  1  257 LYS C NZ  1 
ATOM   934  N N   . TRP A 1 255 ? 134.163 155.689 138.169 1.00 69.70  ?  258 TRP C N   1 
ATOM   935  C CA  . TRP A 1 255 ? 133.520 154.395 137.987 1.00 69.70  ?  258 TRP C CA  1 
ATOM   936  C C   . TRP A 1 255 ? 132.440 154.431 136.912 1.00 69.70  ?  258 TRP C C   1 
ATOM   937  O O   . TRP A 1 255 ? 132.282 153.462 136.163 1.00 69.70  ?  258 TRP C O   1 
ATOM   938  C CB  . TRP A 1 255 ? 132.923 153.914 139.311 1.00 69.70  ?  258 TRP C CB  1 
ATOM   939  C CG  . TRP A 1 255 ? 133.901 153.934 140.442 1.00 69.70  ?  258 TRP C CG  1 
ATOM   940  C CD1 . TRP A 1 255 ? 133.875 154.748 141.534 1.00 69.70  ?  258 TRP C CD1 1 
ATOM   941  C CD2 . TRP A 1 255 ? 135.060 153.104 140.588 1.00 69.70  ?  258 TRP C CD2 1 
ATOM   942  N NE1 . TRP A 1 255 ? 134.942 154.476 142.354 1.00 69.70  ?  258 TRP C NE1 1 
ATOM   943  C CE2 . TRP A 1 255 ? 135.685 153.470 141.795 1.00 69.70  ?  258 TRP C CE2 1 
ATOM   944  C CE3 . TRP A 1 255 ? 135.627 152.087 139.816 1.00 69.70  ?  258 TRP C CE3 1 
ATOM   945  C CZ2 . TRP A 1 255 ? 136.848 152.855 142.248 1.00 69.70  ?  258 TRP C CZ2 1 
ATOM   946  C CZ3 . TRP A 1 255 ? 136.782 151.478 140.267 1.00 69.70  ?  258 TRP C CZ3 1 
ATOM   947  C CH2 . TRP A 1 255 ? 137.380 151.864 141.471 1.00 69.70  ?  258 TRP C CH2 1 
ATOM   948  N N   . PHE A 1 256 ? 131.693 155.526 136.825 1.00 72.52  ?  259 PHE C N   1 
ATOM   949  C CA  . PHE A 1 256 ? 130.641 155.672 135.819 1.00 72.52  ?  259 PHE C CA  1 
ATOM   950  C C   . PHE A 1 256 ? 131.164 156.419 134.593 1.00 72.52  ?  259 PHE C C   1 
ATOM   951  O O   . PHE A 1 256 ? 130.635 157.452 134.184 1.00 72.52  ?  259 PHE C O   1 
ATOM   952  C CB  . PHE A 1 256 ? 129.431 156.379 136.420 1.00 72.52  ?  259 PHE C CB  1 
ATOM   953  C CG  . PHE A 1 256 ? 129.076 155.904 137.796 1.00 72.52  ?  259 PHE C CG  1 
ATOM   954  C CD1 . PHE A 1 256 ? 128.832 154.565 138.038 1.00 72.52  ?  259 PHE C CD1 1 
ATOM   955  C CD2 . PHE A 1 256 ? 128.981 156.797 138.848 1.00 72.52  ?  259 PHE C CD2 1 
ATOM   956  C CE1 . PHE A 1 256 ? 128.504 154.127 139.300 1.00 72.52  ?  259 PHE C CE1 1 
ATOM   957  C CE2 . PHE A 1 256 ? 128.652 156.362 140.114 1.00 72.52  ?  259 PHE C CE2 1 
ATOM   958  C CZ  . PHE A 1 256 ? 128.413 155.024 140.338 1.00 72.52  ?  259 PHE C CZ  1 
ATOM   959  N N   . THR A 1 257 ? 132.227 155.877 134.002 1.00 79.25  ?  260 THR C N   1 
ATOM   960  C CA  . THR A 1 257 ? 132.765 156.442 132.771 1.00 79.25  ?  260 THR C CA  1 
ATOM   961  C C   . THR A 1 257 ? 131.999 155.995 131.535 1.00 79.25  ?  260 THR C C   1 
ATOM   962  O O   . THR A 1 257 ? 132.158 156.607 130.474 1.00 79.25  ?  260 THR C O   1 
ATOM   963  C CB  . THR A 1 257 ? 134.242 156.072 132.615 1.00 79.25  ?  260 THR C CB  1 
ATOM   964  O OG1 . THR A 1 257 ? 134.384 154.646 132.634 1.00 79.25  ?  260 THR C OG1 1 
ATOM   965  C CG2 . THR A 1 257 ? 135.064 156.677 133.739 1.00 79.25  ?  260 THR C CG2 1 
ATOM   966  N N   . ASP A 1 258 ? 131.176 154.951 131.645 1.00 78.47  ?  261 ASP C N   1 
ATOM   967  C CA  . ASP A 1 258 ? 130.374 154.495 130.518 1.00 78.47  ?  261 ASP C CA  1 
ATOM   968  C C   . ASP A 1 258 ? 128.957 154.110 130.928 1.00 78.47  ?  261 ASP C C   1 
ATOM   969  O O   . ASP A 1 258 ? 128.220 153.557 130.102 1.00 78.47  ?  261 ASP C O   1 
ATOM   970  C CB  . ASP A 1 258 ? 131.052 153.310 129.818 1.00 78.47  ?  261 ASP C CB  1 
ATOM   971  C CG  . ASP A 1 258 ? 131.428 152.201 130.781 1.00 78.47  ?  261 ASP C CG  1 
ATOM   972  O OD1 . ASP A 1 258 ? 131.157 152.341 131.992 1.00 78.47  ?  261 ASP C OD1 1 
ATOM   973  O OD2 . ASP A 1 258 ? 132.003 151.190 130.326 1.00 78.47  -1 261 ASP C OD2 1 
ATOM   974  N N   . THR A 1 259 ? 128.555 154.378 132.167 1.00 70.66  ?  262 THR C N   1 
ATOM   975  C CA  . THR A 1 259 ? 127.213 154.061 132.638 1.00 70.66  ?  262 THR C CA  1 
ATOM   976  C C   . THR A 1 259 ? 126.287 155.226 132.313 1.00 70.66  ?  262 THR C C   1 
ATOM   977  O O   . THR A 1 259 ? 126.487 156.340 132.807 1.00 70.66  ?  262 THR C O   1 
ATOM   978  C CB  . THR A 1 259 ? 127.217 153.778 134.139 1.00 70.66  ?  262 THR C CB  1 
ATOM   979  O OG1 . THR A 1 259 ? 127.834 152.509 134.386 1.00 70.66  ?  262 THR C OG1 1 
ATOM   980  C CG2 . THR A 1 259 ? 125.799 153.755 134.681 1.00 70.66  ?  262 THR C CG2 1 
ATOM   981  N N   . SER A 1 260 ? 125.278 154.968 131.486 1.00 68.25  ?  263 SER C N   1 
ATOM   982  C CA  . SER A 1 260 ? 124.373 156.022 131.058 1.00 68.25  ?  263 SER C CA  1 
ATOM   983  C C   . SER A 1 260 ? 123.516 156.510 132.219 1.00 68.25  ?  263 SER C C   1 
ATOM   984  O O   . SER A 1 260 ? 123.263 155.786 133.187 1.00 68.25  ?  263 SER C O   1 
ATOM   985  C CB  . SER A 1 260 ? 123.482 155.530 129.920 1.00 68.25  ?  263 SER C CB  1 
ATOM   986  O OG  . SER A 1 260 ? 124.252 154.912 128.904 1.00 68.25  ?  263 SER C OG  1 
ATOM   987  N N   . ILE A 1 261 ? 123.069 157.758 132.113 1.00 63.21  ?  264 ILE C N   1 
ATOM   988  C CA  . ILE A 1 261 ? 122.277 158.408 133.147 1.00 63.21  ?  264 ILE C CA  1 
ATOM   989  C C   . ILE A 1 261 ? 120.931 158.795 132.556 1.00 63.21  ?  264 ILE C C   1 
ATOM   990  O O   . ILE A 1 261 ? 120.870 159.461 131.517 1.00 63.21  ?  264 ILE C O   1 
ATOM   991  C CB  . ILE A 1 261 ? 122.996 159.641 133.721 1.00 63.21  ?  264 ILE C CB  1 
ATOM   992  C CG1 . ILE A 1 261 ? 124.333 159.235 134.341 1.00 63.21  ?  264 ILE C CG1 1 
ATOM   993  C CG2 . ILE A 1 261 ? 122.117 160.339 134.743 1.00 63.21  ?  264 ILE C CG2 1 
ATOM   994  C CD1 . ILE A 1 261 ? 124.959 160.305 135.200 1.00 63.21  ?  264 ILE C CD1 1 
ATOM   995  N N   . ILE A 1 262 ? 119.860 158.374 133.217 1.00 61.91  ?  265 ILE C N   1 
ATOM   996  C CA  . ILE A 1 262 ? 118.501 158.769 132.875 1.00 61.91  ?  265 ILE C CA  1 
ATOM   997  C C   . ILE A 1 262 ? 118.108 159.879 133.838 1.00 61.91  ?  265 ILE C C   1 
ATOM   998  O O   . ILE A 1 262 ? 117.949 159.643 135.040 1.00 61.91  ?  265 ILE C O   1 
ATOM   999  C CB  . ILE A 1 262 ? 117.530 157.585 132.959 1.00 61.91  ?  265 ILE C CB  1 
ATOM   1000 C CG1 . ILE A 1 262 ? 118.028 156.426 132.095 1.00 61.91  ?  265 ILE C CG1 1 
ATOM   1001 C CG2 . ILE A 1 262 ? 116.135 158.008 132.537 1.00 61.91  ?  265 ILE C CG2 1 
ATOM   1002 C CD1 . ILE A 1 262 ? 117.467 155.084 132.499 1.00 61.91  ?  265 ILE C CD1 1 
ATOM   1003 N N   . LEU A 1 263 ? 117.955 161.092 133.321 1.00 69.11  ?  266 LEU C N   1 
ATOM   1004 C CA  . LEU A 1 263 ? 117.659 162.259 134.141 1.00 69.11  ?  266 LEU C CA  1 
ATOM   1005 C C   . LEU A 1 263 ? 116.153 162.480 134.170 1.00 69.11  ?  266 LEU C C   1 
ATOM   1006 O O   . LEU A 1 263 ? 115.531 162.679 133.121 1.00 69.11  ?  266 LEU C O   1 
ATOM   1007 C CB  . LEU A 1 263 ? 118.378 163.495 133.603 1.00 69.11  ?  266 LEU C CB  1 
ATOM   1008 C CG  . LEU A 1 263 ? 118.350 164.743 134.485 1.00 69.11  ?  266 LEU C CG  1 
ATOM   1009 C CD1 . LEU A 1 263 ? 119.246 164.560 135.695 1.00 69.11  ?  266 LEU C CD1 1 
ATOM   1010 C CD2 . LEU A 1 263 ? 118.766 165.965 133.689 1.00 69.11  ?  266 LEU C CD2 1 
ATOM   1011 N N   . PHE A 1 264 ? 115.573 162.446 135.365 1.00 75.51  ?  267 PHE C N   1 
ATOM   1012 C CA  . PHE A 1 264 ? 114.143 162.652 135.562 1.00 75.51  ?  267 PHE C CA  1 
ATOM   1013 C C   . PHE A 1 264 ? 113.939 164.001 136.236 1.00 75.51  ?  267 PHE C C   1 
ATOM   1014 O O   . PHE A 1 264 ? 114.272 164.169 137.415 1.00 75.51  ?  267 PHE C O   1 
ATOM   1015 C CB  . PHE A 1 264 ? 113.537 161.528 136.398 1.00 75.51  ?  267 PHE C CB  1 
ATOM   1016 C CG  . PHE A 1 264 ? 113.039 160.370 135.587 1.00 75.51  ?  267 PHE C CG  1 
ATOM   1017 C CD1 . PHE A 1 264 ? 112.158 160.571 134.540 1.00 75.51  ?  267 PHE C CD1 1 
ATOM   1018 C CD2 . PHE A 1 264 ? 113.444 159.081 135.876 1.00 75.51  ?  267 PHE C CD2 1 
ATOM   1019 C CE1 . PHE A 1 264 ? 111.696 159.508 133.793 1.00 75.51  ?  267 PHE C CE1 1 
ATOM   1020 C CE2 . PHE A 1 264 ? 112.985 158.014 135.133 1.00 75.51  ?  267 PHE C CE2 1 
ATOM   1021 C CZ  . PHE A 1 264 ? 112.110 158.228 134.091 1.00 75.51  ?  267 PHE C CZ  1 
ATOM   1022 N N   . LEU A 1 265 ? 113.383 164.954 135.493 1.00 81.84  ?  268 LEU C N   1 
ATOM   1023 C CA  . LEU A 1 265 ? 113.066 166.276 136.028 1.00 81.84  ?  268 LEU C CA  1 
ATOM   1024 C C   . LEU A 1 265 ? 111.623 166.247 136.518 1.00 81.84  ?  268 LEU C C   1 
ATOM   1025 O O   . LEU A 1 265 ? 110.681 166.264 135.724 1.00 81.84  ?  268 LEU C O   1 
ATOM   1026 C CB  . LEU A 1 265 ? 113.295 167.352 134.974 1.00 81.84  ?  268 LEU C CB  1 
ATOM   1027 C CG  . LEU A 1 265 ? 114.699 167.359 134.365 1.00 81.84  ?  268 LEU C CG  1 
ATOM   1028 C CD1 . LEU A 1 265 ? 114.854 168.488 133.365 1.00 81.84  ?  268 LEU C CD1 1 
ATOM   1029 C CD2 . LEU A 1 265 ? 115.756 167.460 135.450 1.00 81.84  ?  268 LEU C CD2 1 
ATOM   1030 N N   . ASN A 1 266 ? 111.457 166.204 137.836 1.00 89.64  ?  269 ASN C N   1 
ATOM   1031 C CA  . ASN A 1 266 ? 110.165 166.010 138.472 1.00 89.64  ?  269 ASN C CA  1 
ATOM   1032 C C   . ASN A 1 266 ? 109.447 167.343 138.669 1.00 89.64  ?  269 ASN C C   1 
ATOM   1033 O O   . ASN A 1 266 ? 109.979 168.418 138.383 1.00 89.64  ?  269 ASN C O   1 
ATOM   1034 C CB  . ASN A 1 266 ? 110.345 165.296 139.810 1.00 89.64  ?  269 ASN C CB  1 
ATOM   1035 C CG  . ASN A 1 266 ? 110.884 163.889 139.655 1.00 89.64  ?  269 ASN C CG  1 
ATOM   1036 O OD1 . ASN A 1 266 ? 110.445 163.137 138.789 1.00 89.64  ?  269 ASN C OD1 1 
ATOM   1037 N ND2 . ASN A 1 266 ? 111.849 163.530 140.491 1.00 89.64  ?  269 ASN C ND2 1 
ATOM   1038 N N   . LYS A 1 267 ? 108.214 167.262 139.172 1.00 99.13  ?  270 LYS C N   1 
ATOM   1039 C CA  . LYS A 1 267 ? 107.422 168.424 139.579 1.00 99.13  ?  270 LYS C CA  1 
ATOM   1040 C C   . LYS A 1 267 ? 107.258 169.425 138.432 1.00 99.13  ?  270 LYS C C   1 
ATOM   1041 O O   . LYS A 1 267 ? 107.644 170.589 138.528 1.00 99.13  ?  270 LYS C O   1 
ATOM   1042 C CB  . LYS A 1 267 ? 108.039 169.096 140.810 1.00 99.13  ?  270 LYS C CB  1 
ATOM   1043 C CG  . LYS A 1 267 ? 108.500 168.127 141.885 1.00 99.13  ?  270 LYS C CG  1 
ATOM   1044 C CD  . LYS A 1 267 ? 107.342 167.669 142.752 1.00 99.13  ?  270 LYS C CD  1 
ATOM   1045 C CE  . LYS A 1 267 ? 107.802 166.662 143.793 1.00 99.13  ?  270 LYS C CE  1 
ATOM   1046 N NZ  . LYS A 1 267 ? 108.849 167.228 144.686 1.00 99.13  1  270 LYS C NZ  1 
ATOM   1047 N N   . LYS A 1 268 ? 106.675 168.945 137.332 1.00 104.07 ?  271 LYS C N   1 
ATOM   1048 C CA  . LYS A 1 268 ? 106.439 169.816 136.184 1.00 104.07 ?  271 LYS C CA  1 
ATOM   1049 C C   . LYS A 1 268 ? 105.413 170.896 136.508 1.00 104.07 ?  271 LYS C C   1 
ATOM   1050 O O   . LYS A 1 268 ? 105.623 172.078 136.214 1.00 104.07 ?  271 LYS C O   1 
ATOM   1051 C CB  . LYS A 1 268 ? 105.981 168.987 134.984 1.00 104.07 ?  271 LYS C CB  1 
ATOM   1052 C CG  . LYS A 1 268 ? 107.100 168.262 134.263 1.00 104.07 ?  271 LYS C CG  1 
ATOM   1053 C CD  . LYS A 1 268 ? 106.633 167.745 132.913 1.00 104.07 ?  271 LYS C CD  1 
ATOM   1054 C CE  . LYS A 1 268 ? 105.421 166.839 133.054 1.00 104.07 ?  271 LYS C CE  1 
ATOM   1055 N NZ  . LYS A 1 268 ? 104.976 166.298 131.739 1.00 104.07 1  271 LYS C NZ  1 
ATOM   1056 N N   . ASP A 1 269 ? 104.292 170.505 137.119 1.00 109.52 ?  272 ASP C N   1 
ATOM   1057 C CA  . ASP A 1 269 ? 103.211 171.453 137.375 1.00 109.52 ?  272 ASP C CA  1 
ATOM   1058 C C   . ASP A 1 269 ? 103.618 172.498 138.406 1.00 109.52 ?  272 ASP C C   1 
ATOM   1059 O O   . ASP A 1 269 ? 103.371 173.697 138.223 1.00 109.52 ?  272 ASP C O   1 
ATOM   1060 C CB  . ASP A 1 269 ? 101.958 170.704 137.832 1.00 109.52 ?  272 ASP C CB  1 
ATOM   1061 N N   . LEU A 1 270 ? 104.231 172.061 139.509 1.00 112.21 ?  273 LEU C N   1 
ATOM   1062 C CA  . LEU A 1 270 ? 104.664 173.005 140.533 1.00 112.21 ?  273 LEU C CA  1 
ATOM   1063 C C   . LEU A 1 270 ? 105.760 173.922 140.003 1.00 112.21 ?  273 LEU C C   1 
ATOM   1064 O O   . LEU A 1 270 ? 105.810 175.109 140.350 1.00 112.21 ?  273 LEU C O   1 
ATOM   1065 C CB  . LEU A 1 270 ? 105.129 172.250 141.778 1.00 112.21 ?  273 LEU C CB  1 
ATOM   1066 C CG  . LEU A 1 270 ? 105.556 173.095 142.977 1.00 112.21 ?  273 LEU C CG  1 
ATOM   1067 C CD1 . LEU A 1 270 ? 104.378 173.912 143.472 1.00 112.21 ?  273 LEU C CD1 1 
ATOM   1068 C CD2 . LEU A 1 270 ? 106.083 172.202 144.090 1.00 112.21 ?  273 LEU C CD2 1 
ATOM   1069 N N   . PHE A 1 271 ? 106.644 173.392 139.154 1.00 110.34 ?  274 PHE C N   1 
ATOM   1070 C CA  . PHE A 1 271 ? 107.631 174.244 138.500 1.00 110.34 ?  274 PHE C CA  1 
ATOM   1071 C C   . PHE A 1 271 ? 106.959 175.285 137.617 1.00 110.34 ?  274 PHE C C   1 
ATOM   1072 O O   . PHE A 1 271 ? 107.389 176.441 137.578 1.00 110.34 ?  274 PHE C O   1 
ATOM   1073 C CB  . PHE A 1 271 ? 108.606 173.407 137.675 1.00 110.34 ?  274 PHE C CB  1 
ATOM   1074 C CG  . PHE A 1 271 ? 109.576 174.229 136.877 1.00 110.34 ?  274 PHE C CG  1 
ATOM   1075 C CD1 . PHE A 1 271 ? 110.501 175.040 137.510 1.00 110.34 ?  274 PHE C CD1 1 
ATOM   1076 C CD2 . PHE A 1 271 ? 109.554 174.200 135.494 1.00 110.34 ?  274 PHE C CD2 1 
ATOM   1077 C CE1 . PHE A 1 271 ? 111.392 175.799 136.779 1.00 110.34 ?  274 PHE C CE1 1 
ATOM   1078 C CE2 . PHE A 1 271 ? 110.441 174.959 134.758 1.00 110.34 ?  274 PHE C CE2 1 
ATOM   1079 C CZ  . PHE A 1 271 ? 111.362 175.759 135.401 1.00 110.34 ?  274 PHE C CZ  1 
ATOM   1080 N N   . GLU A 1 272 ? 105.911 174.891 136.890 1.00 117.78 ?  275 GLU C N   1 
ATOM   1081 C CA  . GLU A 1 272 ? 105.181 175.850 136.066 1.00 117.78 ?  275 GLU C CA  1 
ATOM   1082 C C   . GLU A 1 272 ? 104.565 176.950 136.923 1.00 117.78 ?  275 GLU C C   1 
ATOM   1083 O O   . GLU A 1 272 ? 104.661 178.141 136.597 1.00 117.78 ?  275 GLU C O   1 
ATOM   1084 C CB  . GLU A 1 272 ? 104.102 175.128 135.257 1.00 117.78 ?  275 GLU C CB  1 
ATOM   1085 C CG  . GLU A 1 272 ? 103.518 175.948 134.119 1.00 117.78 ?  275 GLU C CG  1 
ATOM   1086 C CD  . GLU A 1 272 ? 102.579 175.142 133.241 1.00 117.78 ?  275 GLU C CD  1 
ATOM   1087 O OE1 . GLU A 1 272 ? 102.311 173.969 133.575 1.00 117.78 ?  275 GLU C OE1 1 
ATOM   1088 O OE2 . GLU A 1 272 ? 102.109 175.682 132.218 1.00 117.78 -1 275 GLU C OE2 1 
ATOM   1089 N N   . GLU A 1 273 ? 103.936 176.564 138.035 1.00 119.24 ?  276 GLU C N   1 
ATOM   1090 C CA  . GLU A 1 273 ? 103.331 177.555 138.921 1.00 119.24 ?  276 GLU C CA  1 
ATOM   1091 C C   . GLU A 1 273 ? 104.380 178.502 139.492 1.00 119.24 ?  276 GLU C C   1 
ATOM   1092 O O   . GLU A 1 273 ? 104.151 179.714 139.576 1.00 119.24 ?  276 GLU C O   1 
ATOM   1093 C CB  . GLU A 1 273 ? 102.562 176.870 140.053 1.00 119.24 ?  276 GLU C CB  1 
ATOM   1094 C CG  . GLU A 1 273 ? 101.579 175.799 139.609 1.00 119.24 ?  276 GLU C CG  1 
ATOM   1095 C CD  . GLU A 1 273 ? 100.450 176.344 138.752 1.00 119.24 ?  276 GLU C CD  1 
ATOM   1096 O OE1 . GLU A 1 273 ? 100.196 177.567 138.793 1.00 119.24 ?  276 GLU C OE1 1 
ATOM   1097 O OE2 . GLU A 1 273 ? 99.812  175.544 138.035 1.00 119.24 -1 276 GLU C OE2 1 
ATOM   1098 N N   . LYS A 1 274 ? 105.538 177.971 139.887 1.00 115.68 ?  277 LYS C N   1 
ATOM   1099 C CA  . LYS A 1 274 ? 106.574 178.814 140.467 1.00 115.68 ?  277 LYS C CA  1 
ATOM   1100 C C   . LYS A 1 274 ? 107.332 179.633 139.429 1.00 115.68 ?  277 LYS C C   1 
ATOM   1101 O O   . LYS A 1 274 ? 107.942 180.644 139.791 1.00 115.68 ?  277 LYS C O   1 
ATOM   1102 C CB  . LYS A 1 274 ? 107.559 177.965 141.272 1.00 115.68 ?  277 LYS C CB  1 
ATOM   1103 C CG  . LYS A 1 274 ? 107.176 177.809 142.735 1.00 115.68 ?  277 LYS C CG  1 
ATOM   1104 C CD  . LYS A 1 274 ? 108.338 177.284 143.560 1.00 115.68 ?  277 LYS C CD  1 
ATOM   1105 C CE  . LYS A 1 274 ? 108.262 175.778 143.721 1.00 115.68 ?  277 LYS C CE  1 
ATOM   1106 N NZ  . LYS A 1 274 ? 109.141 175.291 144.820 1.00 115.68 1  277 LYS C NZ  1 
ATOM   1107 N N   . ILE A 1 275 ? 107.309 179.234 138.160 1.00 117.44 ?  278 ILE C N   1 
ATOM   1108 C CA  . ILE A 1 275 ? 108.010 180.004 137.140 1.00 117.44 ?  278 ILE C CA  1 
ATOM   1109 C C   . ILE A 1 275 ? 107.104 181.073 136.537 1.00 117.44 ?  278 ILE C C   1 
ATOM   1110 O O   . ILE A 1 275 ? 107.598 182.085 136.029 1.00 117.44 ?  278 ILE C O   1 
ATOM   1111 C CB  . ILE A 1 275 ? 108.584 179.080 136.050 1.00 117.44 ?  278 ILE C CB  1 
ATOM   1112 C CG1 . ILE A 1 275 ? 109.578 179.838 135.168 1.00 117.44 ?  278 ILE C CG1 1 
ATOM   1113 C CG2 . ILE A 1 275 ? 107.481 178.523 135.173 1.00 117.44 ?  278 ILE C CG2 1 
ATOM   1114 C CD1 . ILE A 1 275 ? 110.826 180.278 135.897 1.00 117.44 ?  278 ILE C CD1 1 
ATOM   1115 N N   . LYS A 1 276 ? 105.783 180.880 136.588 1.00 121.23 ?  279 LYS C N   1 
ATOM   1116 C CA  . LYS A 1 276 ? 104.883 181.953 136.176 1.00 121.23 ?  279 LYS C CA  1 
ATOM   1117 C C   . LYS A 1 276 ? 105.000 183.154 137.107 1.00 121.23 ?  279 LYS C C   1 
ATOM   1118 O O   . LYS A 1 276 ? 104.867 184.303 136.671 1.00 121.23 ?  279 LYS C O   1 
ATOM   1119 C CB  . LYS A 1 276 ? 103.441 181.451 136.122 1.00 121.23 ?  279 LYS C CB  1 
ATOM   1120 C CG  . LYS A 1 276 ? 103.182 180.421 135.034 1.00 121.23 ?  279 LYS C CG  1 
ATOM   1121 C CD  . LYS A 1 276 ? 101.704 180.087 134.928 1.00 121.23 ?  279 LYS C CD  1 
ATOM   1122 C CE  . LYS A 1 276 ? 101.250 179.222 136.091 1.00 121.23 ?  279 LYS C CE  1 
ATOM   1123 N NZ  . LYS A 1 276 ? 99.832  178.795 135.944 1.00 121.23 1  279 LYS C NZ  1 
ATOM   1124 N N   . LYS A 1 277 ? 105.251 182.909 138.395 1.00 120.67 ?  280 LYS C N   1 
ATOM   1125 C CA  . LYS A 1 277 ? 105.389 183.977 139.381 1.00 120.67 ?  280 LYS C CA  1 
ATOM   1126 C C   . LYS A 1 277 ? 106.847 184.359 139.619 1.00 120.67 ?  280 LYS C C   1 
ATOM   1127 O O   . LYS A 1 277 ? 107.232 185.513 139.411 1.00 120.67 ?  280 LYS C O   1 
ATOM   1128 C CB  . LYS A 1 277 ? 104.723 183.559 140.699 1.00 120.67 ?  280 LYS C CB  1 
ATOM   1129 N N   . SER A 1 278 ? 107.670 183.405 140.053 1.00 120.37 ?  281 SER C N   1 
ATOM   1130 C CA  . SER A 1 278 ? 109.059 183.689 140.396 1.00 120.37 ?  281 SER C CA  1 
ATOM   1131 C C   . SER A 1 278 ? 109.953 183.452 139.187 1.00 120.37 ?  281 SER C C   1 
ATOM   1132 O O   . SER A 1 278 ? 109.925 182.353 138.617 1.00 120.37 ?  281 SER C O   1 
ATOM   1133 C CB  . SER A 1 278 ? 109.515 182.822 141.556 1.00 120.37 ?  281 SER C CB  1 
ATOM   1134 O OG  . SER A 1 278 ? 110.929 182.742 141.606 1.00 120.37 ?  281 SER C OG  1 
ATOM   1135 N N   . PRO A 1 279 ? 110.748 184.432 138.764 1.00 120.73 ?  282 PRO C N   1 
ATOM   1136 C CA  . PRO A 1 279 ? 111.624 184.227 137.607 1.00 120.73 ?  282 PRO C CA  1 
ATOM   1137 C C   . PRO A 1 279 ? 112.746 183.245 137.912 1.00 120.73 ?  282 PRO C C   1 
ATOM   1138 O O   . PRO A 1 279 ? 113.152 183.050 139.059 1.00 120.73 ?  282 PRO C O   1 
ATOM   1139 C CB  . PRO A 1 279 ? 112.176 185.629 137.328 1.00 120.73 ?  282 PRO C CB  1 
ATOM   1140 C CG  . PRO A 1 279 ? 112.119 186.317 138.648 1.00 120.73 ?  282 PRO C CG  1 
ATOM   1141 C CD  . PRO A 1 279 ? 110.903 185.775 139.350 1.00 120.73 ?  282 PRO C CD  1 
ATOM   1142 N N   . LEU A 1 280 ? 113.248 182.620 136.844 1.00 117.67 ?  283 LEU C N   1 
ATOM   1143 C CA  . LEU A 1 280 ? 114.343 181.665 136.960 1.00 117.67 ?  283 LEU C CA  1 
ATOM   1144 C C   . LEU A 1 280 ? 115.666 182.323 137.332 1.00 117.67 ?  283 LEU C C   1 
ATOM   1145 O O   . LEU A 1 280 ? 116.612 181.612 137.687 1.00 117.67 ?  283 LEU C O   1 
ATOM   1146 C CB  . LEU A 1 280 ? 114.501 180.892 135.649 1.00 117.67 ?  283 LEU C CB  1 
ATOM   1147 C CG  . LEU A 1 280 ? 115.280 179.574 135.693 1.00 117.67 ?  283 LEU C CG  1 
ATOM   1148 C CD1 . LEU A 1 280 ? 114.474 178.493 136.394 1.00 117.67 ?  283 LEU C CD1 1 
ATOM   1149 C CD2 . LEU A 1 280 ? 115.673 179.132 134.293 1.00 117.67 ?  283 LEU C CD2 1 
ATOM   1150 N N   . THR A 1 281 ? 115.754 183.654 137.270 1.00 120.52 ?  284 THR C N   1 
ATOM   1151 C CA  . THR A 1 281 ? 117.006 184.337 137.578 1.00 120.52 ?  284 THR C CA  1 
ATOM   1152 C C   . THR A 1 281 ? 117.417 184.168 139.035 1.00 120.52 ?  284 THR C C   1 
ATOM   1153 O O   . THR A 1 281 ? 118.573 184.446 139.375 1.00 120.52 ?  284 THR C O   1 
ATOM   1154 C CB  . THR A 1 281 ? 116.892 185.825 137.244 1.00 120.52 ?  284 THR C CB  1 
ATOM   1155 O OG1 . THR A 1 281 ? 116.125 186.487 138.258 1.00 120.52 ?  284 THR C OG1 1 
ATOM   1156 C CG2 . THR A 1 281 ? 116.213 186.016 135.896 1.00 120.52 ?  284 THR C CG2 1 
ATOM   1157 N N   . ILE A 1 282 ? 116.501 183.730 139.901 1.00 118.97 ?  285 ILE C N   1 
ATOM   1158 C CA  . ILE A 1 282 ? 116.849 183.497 141.299 1.00 118.97 ?  285 ILE C CA  1 
ATOM   1159 C C   . ILE A 1 282 ? 117.889 182.391 141.412 1.00 118.97 ?  285 ILE C C   1 
ATOM   1160 O O   . ILE A 1 282 ? 118.863 182.506 142.166 1.00 118.97 ?  285 ILE C O   1 
ATOM   1161 C CB  . ILE A 1 282 ? 115.586 183.173 142.117 1.00 118.97 ?  285 ILE C CB  1 
ATOM   1162 C CG1 . ILE A 1 282 ? 114.584 184.325 142.026 1.00 118.97 ?  285 ILE C CG1 1 
ATOM   1163 C CG2 . ILE A 1 282 ? 115.945 182.887 143.566 1.00 118.97 ?  285 ILE C CG2 1 
ATOM   1164 C CD1 . ILE A 1 282 ? 115.108 185.633 142.574 1.00 118.97 ?  285 ILE C CD1 1 
ATOM   1165 N N   . CYS A 1 283 ? 117.703 181.303 140.663 1.00 116.18 ?  286 CYS C N   1 
ATOM   1166 C CA  . CYS A 1 283 ? 118.658 180.201 140.702 1.00 116.18 ?  286 CYS C CA  1 
ATOM   1167 C C   . CYS A 1 283 ? 119.894 180.506 139.863 1.00 116.18 ?  286 CYS C C   1 
ATOM   1168 O O   . CYS A 1 283 ? 121.026 180.332 140.327 1.00 116.18 ?  286 CYS C O   1 
ATOM   1169 C CB  . CYS A 1 283 ? 117.992 178.911 140.221 1.00 116.18 ?  286 CYS C CB  1 
ATOM   1170 S SG  . CYS A 1 283 ? 119.066 177.460 140.273 1.00 116.18 ?  286 CYS C SG  1 
ATOM   1171 N N   . TYR A 1 284 ? 119.695 180.960 138.629 1.00 116.69 ?  287 TYR C N   1 
ATOM   1172 C CA  . TYR A 1 284 ? 120.803 181.256 137.728 1.00 116.69 ?  287 TYR C CA  1 
ATOM   1173 C C   . TYR A 1 284 ? 120.866 182.752 137.460 1.00 116.69 ?  287 TYR C C   1 
ATOM   1174 O O   . TYR A 1 284 ? 120.035 183.274 136.700 1.00 116.69 ?  287 TYR C O   1 
ATOM   1175 C CB  . TYR A 1 284 ? 120.647 180.487 136.416 1.00 116.69 ?  287 TYR C CB  1 
ATOM   1176 C CG  . TYR A 1 284 ? 120.644 178.984 136.578 1.00 116.69 ?  287 TYR C CG  1 
ATOM   1177 C CD1 . TYR A 1 284 ? 121.832 178.269 136.631 1.00 116.69 ?  287 TYR C CD1 1 
ATOM   1178 C CD2 . TYR A 1 284 ? 119.451 178.280 136.677 1.00 116.69 ?  287 TYR C CD2 1 
ATOM   1179 C CE1 . TYR A 1 284 ? 121.834 176.895 136.778 1.00 116.69 ?  287 TYR C CE1 1 
ATOM   1180 C CE2 . TYR A 1 284 ? 119.443 176.907 136.824 1.00 116.69 ?  287 TYR C CE2 1 
ATOM   1181 C CZ  . TYR A 1 284 ? 120.637 176.220 136.874 1.00 116.69 ?  287 TYR C CZ  1 
ATOM   1182 O OH  . TYR A 1 284 ? 120.633 174.852 137.021 1.00 116.69 ?  287 TYR C OH  1 
ATOM   1183 N N   . PRO A 1 285 ? 121.814 183.480 138.055 1.00 121.51 ?  288 PRO C N   1 
ATOM   1184 C CA  . PRO A 1 285 ? 121.904 184.924 137.783 1.00 121.51 ?  288 PRO C CA  1 
ATOM   1185 C C   . PRO A 1 285 ? 122.225 185.251 136.335 1.00 121.51 ?  288 PRO C C   1 
ATOM   1186 O O   . PRO A 1 285 ? 121.888 186.346 135.868 1.00 121.51 ?  288 PRO C O   1 
ATOM   1187 C CB  . PRO A 1 285 ? 123.021 185.386 138.729 1.00 121.51 ?  288 PRO C CB  1 
ATOM   1188 C CG  . PRO A 1 285 ? 123.842 184.163 138.969 1.00 121.51 ?  288 PRO C CG  1 
ATOM   1189 C CD  . PRO A 1 285 ? 122.876 183.015 138.962 1.00 121.51 ?  288 PRO C CD  1 
ATOM   1190 N N   . GLU A 1 286 ? 122.865 184.336 135.609 1.00 119.23 ?  289 GLU C N   1 
ATOM   1191 C CA  . GLU A 1 286 ? 123.272 184.588 134.232 1.00 119.23 ?  289 GLU C CA  1 
ATOM   1192 C C   . GLU A 1 286 ? 122.166 184.319 133.221 1.00 119.23 ?  289 GLU C C   1 
ATOM   1193 O O   . GLU A 1 286 ? 122.415 184.427 132.015 1.00 119.23 ?  289 GLU C O   1 
ATOM   1194 C CB  . GLU A 1 286 ? 124.500 183.741 133.886 1.00 119.23 ?  289 GLU C CB  1 
ATOM   1195 N N   . TYR A 1 287 ? 120.965 183.968 133.672 1.00 121.06 ?  290 TYR C N   1 
ATOM   1196 C CA  . TYR A 1 287 ? 119.877 183.671 132.751 1.00 121.06 ?  290 TYR C CA  1 
ATOM   1197 C C   . TYR A 1 287 ? 119.416 184.931 132.030 1.00 121.06 ?  290 TYR C C   1 
ATOM   1198 O O   . TYR A 1 287 ? 119.421 186.030 132.593 1.00 121.06 ?  290 TYR C O   1 
ATOM   1199 C CB  . TYR A 1 287 ? 118.704 183.039 133.499 1.00 121.06 ?  290 TYR C CB  1 
ATOM   1200 C CG  . TYR A 1 287 ? 117.615 182.516 132.592 1.00 121.06 ?  290 TYR C CG  1 
ATOM   1201 C CD1 . TYR A 1 287 ? 117.924 181.913 131.380 1.00 121.06 ?  290 TYR C CD1 1 
ATOM   1202 C CD2 . TYR A 1 287 ? 116.277 182.624 132.946 1.00 121.06 ?  290 TYR C CD2 1 
ATOM   1203 C CE1 . TYR A 1 287 ? 116.935 181.434 130.548 1.00 121.06 ?  290 TYR C CE1 1 
ATOM   1204 C CE2 . TYR A 1 287 ? 115.280 182.147 132.119 1.00 121.06 ?  290 TYR C CE2 1 
ATOM   1205 C CZ  . TYR A 1 287 ? 115.616 181.553 130.922 1.00 121.06 ?  290 TYR C CZ  1 
ATOM   1206 O OH  . TYR A 1 287 ? 114.630 181.077 130.093 1.00 121.06 ?  290 TYR C OH  1 
ATOM   1207 N N   . ALA A 1 288 ? 119.017 184.764 130.768 1.00 123.94 ?  291 ALA C N   1 
ATOM   1208 C CA  . ALA A 1 288 ? 118.462 185.858 129.969 1.00 123.94 ?  291 ALA C CA  1 
ATOM   1209 C C   . ALA A 1 288 ? 117.413 185.247 129.038 1.00 123.94 ?  291 ALA C C   1 
ATOM   1210 O O   . ALA A 1 288 ? 117.735 184.766 127.950 1.00 123.94 ?  291 ALA C O   1 
ATOM   1211 C CB  . ALA A 1 288 ? 119.546 186.592 129.193 1.00 123.94 ?  291 ALA C CB  1 
ATOM   1212 N N   . GLY A 1 289 ? 116.162 185.274 129.481 1.00 125.33 ?  292 GLY C N   1 
ATOM   1213 C CA  . GLY A 1 289 ? 115.080 184.704 128.699 1.00 125.33 ?  292 GLY C CA  1 
ATOM   1214 C C   . GLY A 1 289 ? 113.752 184.959 129.377 1.00 125.33 ?  292 GLY C C   1 
ATOM   1215 O O   . GLY A 1 289 ? 113.686 185.474 130.499 1.00 125.33 ?  292 GLY C O   1 
ATOM   1216 N N   . SER A 1 290 ? 112.688 184.586 128.672 1.00 126.16 ?  293 SER C N   1 
ATOM   1217 C CA  . SER A 1 290 ? 111.339 184.780 129.181 1.00 126.16 ?  293 SER C CA  1 
ATOM   1218 C C   . SER A 1 290 ? 111.062 183.842 130.352 1.00 126.16 ?  293 SER C C   1 
ATOM   1219 O O   . SER A 1 290 ? 111.698 182.798 130.507 1.00 126.16 ?  293 SER C O   1 
ATOM   1220 C CB  . SER A 1 290 ? 110.313 184.550 128.072 1.00 126.16 ?  293 SER C CB  1 
ATOM   1221 O OG  . SER A 1 290 ? 110.413 183.236 127.552 1.00 126.16 ?  293 SER C OG  1 
ATOM   1222 N N   . ASN A 1 291 ? 110.114 184.241 131.197 1.00 125.48 ?  294 ASN C N   1 
ATOM   1223 C CA  . ASN A 1 291 ? 109.707 183.431 132.344 1.00 125.48 ?  294 ASN C CA  1 
ATOM   1224 C C   . ASN A 1 291 ? 108.419 182.675 132.017 1.00 125.48 ?  294 ASN C C   1 
ATOM   1225 O O   . ASN A 1 291 ? 107.340 182.950 132.543 1.00 125.48 ?  294 ASN C O   1 
ATOM   1226 C CB  . ASN A 1 291 ? 109.549 184.310 133.581 1.00 125.48 ?  294 ASN C CB  1 
ATOM   1227 C CG  . ASN A 1 291 ? 110.842 184.991 133.978 1.00 125.48 ?  294 ASN C CG  1 
ATOM   1228 O OD1 . ASN A 1 291 ? 111.822 184.333 134.328 1.00 125.48 ?  294 ASN C OD1 1 
ATOM   1229 N ND2 . ASN A 1 291 ? 110.853 186.318 133.926 1.00 125.48 ?  294 ASN C ND2 1 
ATOM   1230 N N   . THR A 1 292 ? 108.554 181.699 131.124 1.00 123.93 ?  295 THR C N   1 
ATOM   1231 C CA  . THR A 1 292 ? 107.444 180.860 130.698 1.00 123.93 ?  295 THR C CA  1 
ATOM   1232 C C   . THR A 1 292 ? 107.820 179.390 130.838 1.00 123.93 ?  295 THR C C   1 
ATOM   1233 O O   . THR A 1 292 ? 108.997 179.028 130.914 1.00 123.93 ?  295 THR C O   1 
ATOM   1234 C CB  . THR A 1 292 ? 107.041 181.164 129.249 1.00 123.93 ?  295 THR C CB  1 
ATOM   1235 O OG1 . THR A 1 292 ? 105.959 180.306 128.863 1.00 123.93 ?  295 THR C OG1 1 
ATOM   1236 C CG2 . THR A 1 292 ? 108.215 180.937 128.311 1.00 123.93 ?  295 THR C CG2 1 
ATOM   1237 N N   . TYR A 1 293 ? 106.795 178.533 130.879 1.00 120.36 ?  296 TYR C N   1 
ATOM   1238 C CA  . TYR A 1 293 ? 107.041 177.099 130.976 1.00 120.36 ?  296 TYR C CA  1 
ATOM   1239 C C   . TYR A 1 293 ? 107.684 176.538 129.714 1.00 120.36 ?  296 TYR C C   1 
ATOM   1240 O O   . TYR A 1 293 ? 108.274 175.454 129.764 1.00 120.36 ?  296 TYR C O   1 
ATOM   1241 C CB  . TYR A 1 293 ? 105.743 176.349 131.276 1.00 120.36 ?  296 TYR C CB  1 
ATOM   1242 C CG  . TYR A 1 293 ? 105.941 174.858 131.431 1.00 120.36 ?  296 TYR C CG  1 
ATOM   1243 C CD1 . TYR A 1 293 ? 106.503 174.331 132.586 1.00 120.36 ?  296 TYR C CD1 1 
ATOM   1244 C CD2 . TYR A 1 293 ? 105.582 173.979 130.418 1.00 120.36 ?  296 TYR C CD2 1 
ATOM   1245 C CE1 . TYR A 1 293 ? 106.695 172.972 132.731 1.00 120.36 ?  296 TYR C CE1 1 
ATOM   1246 C CE2 . TYR A 1 293 ? 105.770 172.618 130.554 1.00 120.36 ?  296 TYR C CE2 1 
ATOM   1247 C CZ  . TYR A 1 293 ? 106.326 172.120 131.713 1.00 120.36 ?  296 TYR C CZ  1 
ATOM   1248 O OH  . TYR A 1 293 ? 106.514 170.766 131.853 1.00 120.36 ?  296 TYR C OH  1 
ATOM   1249 N N   . GLU A 1 294 ? 107.595 177.253 128.589 1.00 122.07 ?  297 GLU C N   1 
ATOM   1250 C CA  . GLU A 1 294 ? 108.335 176.858 127.397 1.00 122.07 ?  297 GLU C CA  1 
ATOM   1251 C C   . GLU A 1 294 ? 109.837 176.870 127.635 1.00 122.07 ?  297 GLU C C   1 
ATOM   1252 O O   . GLU A 1 294 ? 110.580 176.258 126.859 1.00 122.07 ?  297 GLU C O   1 
ATOM   1253 C CB  . GLU A 1 294 ? 107.983 177.779 126.227 1.00 122.07 ?  297 GLU C CB  1 
ATOM   1254 N N   . GLU A 1 295 ? 110.291 177.549 128.686 1.00 122.75 ?  298 GLU C N   1 
ATOM   1255 C CA  . GLU A 1 295 ? 111.672 177.479 129.139 1.00 122.75 ?  298 GLU C CA  1 
ATOM   1256 C C   . GLU A 1 295 ? 111.885 176.205 129.944 1.00 122.75 ?  298 GLU C C   1 
ATOM   1257 O O   . GLU A 1 295 ? 111.066 175.283 129.872 1.00 122.75 ?  298 GLU C O   1 
ATOM   1258 C CB  . GLU A 1 295 ? 112.035 178.718 129.954 1.00 122.75 ?  298 GLU C CB  1 
ATOM   1259 C CG  . GLU A 1 295 ? 111.787 180.010 129.202 1.00 122.75 ?  298 GLU C CG  1 
ATOM   1260 C CD  . GLU A 1 295 ? 112.582 180.099 127.912 1.00 122.75 ?  298 GLU C CD  1 
ATOM   1261 O OE1 . GLU A 1 295 ? 113.715 179.575 127.869 1.00 122.75 ?  298 GLU C OE1 1 
ATOM   1262 O OE2 . GLU A 1 295 ? 112.073 180.695 126.939 1.00 122.75 -1 298 GLU C OE2 1 
ATOM   1263 N N   . ALA A 1 296 ? 113.033 176.109 130.618 1.00 111.57 ?  299 ALA C N   1 
ATOM   1264 C CA  . ALA A 1 296 ? 113.438 174.848 131.243 1.00 111.57 ?  299 ALA C CA  1 
ATOM   1265 C C   . ALA A 1 296 ? 114.113 173.545 130.847 1.00 111.57 ?  299 ALA C C   1 
ATOM   1266 O O   . ALA A 1 296 ? 114.449 172.752 131.719 1.00 111.57 ?  299 ALA C O   1 
ATOM   1267 C CB  . ALA A 1 296 ? 112.333 174.120 131.964 1.00 111.57 ?  299 ALA C CB  1 
ATOM   1268 N N   . ALA A 1 297 ? 114.312 173.289 129.560 1.00 108.57 ?  300 ALA C N   1 
ATOM   1269 C CA  . ALA A 1 297 ? 114.885 172.039 129.116 1.00 108.57 ?  300 ALA C CA  1 
ATOM   1270 C C   . ALA A 1 297 ? 116.061 172.859 128.708 1.00 108.57 ?  300 ALA C C   1 
ATOM   1271 O O   . ALA A 1 297 ? 117.143 172.711 129.268 1.00 108.57 ?  300 ALA C O   1 
ATOM   1272 C CB  . ALA A 1 297 ? 113.939 171.907 127.948 1.00 108.57 ?  300 ALA C CB  1 
ATOM   1273 N N   . ALA A 1 298 ? 115.883 173.739 127.746 1.00 111.42 ?  301 ALA C N   1 
ATOM   1274 C CA  . ALA A 1 298 ? 116.953 174.670 127.420 1.00 111.42 ?  301 ALA C CA  1 
ATOM   1275 C C   . ALA A 1 298 ? 117.203 175.478 128.689 1.00 111.42 ?  301 ALA C C   1 
ATOM   1276 O O   . ALA A 1 298 ? 116.267 176.031 129.275 1.00 111.42 ?  301 ALA C O   1 
ATOM   1277 C CB  . ALA A 1 298 ? 116.483 175.582 126.285 1.00 111.42 ?  301 ALA C CB  1 
ATOM   1278 N N   . TYR A 1 299 ? 118.461 175.525 129.125 1.00 113.30 ?  302 TYR C N   1 
ATOM   1279 C CA  . TYR A 1 299 ? 118.994 176.248 130.283 1.00 113.30 ?  302 TYR C CA  1 
ATOM   1280 C C   . TYR A 1 299 ? 118.714 175.534 131.605 1.00 113.30 ?  302 TYR C C   1 
ATOM   1281 O O   . TYR A 1 299 ? 119.090 176.061 132.655 1.00 113.30 ?  302 TYR C O   1 
ATOM   1282 C CB  . TYR A 1 299 ? 118.481 177.695 130.386 1.00 113.30 ?  302 TYR C CB  1 
ATOM   1283 C CG  . TYR A 1 299 ? 119.436 178.623 131.100 1.00 113.30 ?  302 TYR C CG  1 
ATOM   1284 C CD1 . TYR A 1 299 ? 120.569 179.105 130.460 1.00 113.30 ?  302 TYR C CD1 1 
ATOM   1285 C CD2 . TYR A 1 299 ? 119.216 179.004 132.415 1.00 113.30 ?  302 TYR C CD2 1 
ATOM   1286 C CE1 . TYR A 1 299 ? 121.450 179.949 131.106 1.00 113.30 ?  302 TYR C CE1 1 
ATOM   1287 C CE2 . TYR A 1 299 ? 120.092 179.843 133.070 1.00 113.30 ?  302 TYR C CE2 1 
ATOM   1288 C CZ  . TYR A 1 299 ? 121.206 180.314 132.411 1.00 113.30 ?  302 TYR C CZ  1 
ATOM   1289 O OH  . TYR A 1 299 ? 122.080 181.154 133.062 1.00 113.30 ?  302 TYR C OH  1 
ATOM   1290 N N   . ILE A 1 300 ? 118.063 174.373 131.602 1.00 103.68 ?  303 ILE C N   1 
ATOM   1291 C CA  . ILE A 1 300 ? 118.007 173.533 132.795 1.00 103.68 ?  303 ILE C CA  1 
ATOM   1292 C C   . ILE A 1 300 ? 118.559 172.161 132.438 1.00 103.68 ?  303 ILE C C   1 
ATOM   1293 O O   . ILE A 1 300 ? 119.587 171.728 132.976 1.00 103.68 ?  303 ILE C O   1 
ATOM   1294 C CB  . ILE A 1 300 ? 116.579 173.427 133.360 1.00 103.68 ?  303 ILE C CB  1 
ATOM   1295 C CG1 . ILE A 1 300 ? 116.046 174.806 133.751 1.00 103.68 ?  303 ILE C CG1 1 
ATOM   1296 C CG2 . ILE A 1 300 ? 116.555 172.496 134.559 1.00 103.68 ?  303 ILE C CG2 1 
ATOM   1297 C CD1 . ILE A 1 300 ? 116.847 175.487 134.834 1.00 103.68 ?  303 ILE C CD1 1 
ATOM   1298 N N   . GLN A 1 301 ? 117.885 171.474 131.514 1.00 97.33  ?  304 GLN C N   1 
ATOM   1299 C CA  . GLN A 1 301 ? 118.416 170.219 130.999 1.00 97.33  ?  304 GLN C CA  1 
ATOM   1300 C C   . GLN A 1 301 ? 119.740 170.439 130.283 1.00 97.33  ?  304 GLN C C   1 
ATOM   1301 O O   . GLN A 1 301 ? 120.638 169.596 130.369 1.00 97.33  ?  304 GLN C O   1 
ATOM   1302 C CB  . GLN A 1 301 ? 117.394 169.561 130.070 1.00 97.33  ?  304 GLN C CB  1 
ATOM   1303 C CG  . GLN A 1 301 ? 117.990 168.713 128.962 1.00 97.33  ?  304 GLN C CG  1 
ATOM   1304 C CD  . GLN A 1 301 ? 116.934 168.147 128.036 1.00 97.33  ?  304 GLN C CD  1 
ATOM   1305 O OE1 . GLN A 1 301 ? 115.746 168.433 128.182 1.00 97.33  ?  304 GLN C OE1 1 
ATOM   1306 N NE2 . GLN A 1 301 ? 117.364 167.343 127.071 1.00 97.33  ?  304 GLN C NE2 1 
ATOM   1307 N N   . CYS A 1 302 ? 119.886 171.568 129.585 1.00 101.55 ?  305 CYS C N   1 
ATOM   1308 C CA  . CYS A 1 302 ? 121.153 171.873 128.928 1.00 101.55 ?  305 CYS C CA  1 
ATOM   1309 C C   . CYS A 1 302 ? 122.277 172.037 129.944 1.00 101.55 ?  305 CYS C C   1 
ATOM   1310 O O   . CYS A 1 302 ? 123.382 171.524 129.745 1.00 101.55 ?  305 CYS C O   1 
ATOM   1311 C CB  . CYS A 1 302 ? 121.012 173.129 128.068 1.00 101.55 ?  305 CYS C CB  1 
ATOM   1312 S SG  . CYS A 1 302 ? 119.887 172.939 126.670 1.00 101.55 ?  305 CYS C SG  1 
ATOM   1313 N N   . GLN A 1 303 ? 122.017 172.750 131.042 1.00 100.54 ?  306 GLN C N   1 
ATOM   1314 C CA  . GLN A 1 303 ? 123.042 172.898 132.073 1.00 100.54 ?  306 GLN C CA  1 
ATOM   1315 C C   . GLN A 1 303 ? 123.362 171.567 132.738 1.00 100.54 ?  306 GLN C C   1 
ATOM   1316 O O   . GLN A 1 303 ? 124.524 171.294 133.061 1.00 100.54 ?  306 GLN C O   1 
ATOM   1317 C CB  . GLN A 1 303 ? 122.615 173.929 133.114 1.00 100.54 ?  306 GLN C CB  1 
ATOM   1318 C CG  . GLN A 1 303 ? 122.044 175.190 132.518 1.00 100.54 ?  306 GLN C CG  1 
ATOM   1319 C CD  . GLN A 1 303 ? 123.127 176.174 132.131 1.00 100.54 ?  306 GLN C CD  1 
ATOM   1320 O OE1 . GLN A 1 303 ? 124.210 176.182 132.715 1.00 100.54 ?  306 GLN C OE1 1 
ATOM   1321 N NE2 . GLN A 1 303 ? 122.845 177.004 131.136 1.00 100.54 ?  306 GLN C NE2 1 
ATOM   1322 N N   . PHE A 1 304 ? 122.348 170.729 132.962 1.00 89.62  ?  307 PHE C N   1 
ATOM   1323 C CA  . PHE A 1 304 ? 122.613 169.417 133.543 1.00 89.62  ?  307 PHE C CA  1 
ATOM   1324 C C   . PHE A 1 304 ? 123.446 168.553 132.603 1.00 89.62  ?  307 PHE C C   1 
ATOM   1325 O O   . PHE A 1 304 ? 124.338 167.823 133.050 1.00 89.62  ?  307 PHE C O   1 
ATOM   1326 C CB  . PHE A 1 304 ? 121.300 168.726 133.902 1.00 89.62  ?  307 PHE C CB  1 
ATOM   1327 C CG  . PHE A 1 304 ? 120.860 168.971 135.315 1.00 89.62  ?  307 PHE C CG  1 
ATOM   1328 C CD1 . PHE A 1 304 ? 121.379 168.220 136.354 1.00 89.62  ?  307 PHE C CD1 1 
ATOM   1329 C CD2 . PHE A 1 304 ? 119.936 169.959 135.605 1.00 89.62  ?  307 PHE C CD2 1 
ATOM   1330 C CE1 . PHE A 1 304 ? 120.980 168.445 137.654 1.00 89.62  ?  307 PHE C CE1 1 
ATOM   1331 C CE2 . PHE A 1 304 ? 119.533 170.188 136.904 1.00 89.62  ?  307 PHE C CE2 1 
ATOM   1332 C CZ  . PHE A 1 304 ? 120.056 169.430 137.930 1.00 89.62  ?  307 PHE C CZ  1 
ATOM   1333 N N   . GLU A 1 305 ? 123.177 168.626 131.299 1.00 92.17  ?  308 GLU C N   1 
ATOM   1334 C CA  . GLU A 1 305 ? 123.927 167.829 130.336 1.00 92.17  ?  308 GLU C CA  1 
ATOM   1335 C C   . GLU A 1 305 ? 125.332 168.370 130.106 1.00 92.17  ?  308 GLU C C   1 
ATOM   1336 O O   . GLU A 1 305 ? 126.239 167.599 129.776 1.00 92.17  ?  308 GLU C O   1 
ATOM   1337 C CB  . GLU A 1 305 ? 123.166 167.759 129.011 1.00 92.17  ?  308 GLU C CB  1 
ATOM   1338 C CG  . GLU A 1 305 ? 121.894 166.929 129.072 1.00 92.17  ?  308 GLU C CG  1 
ATOM   1339 C CD  . GLU A 1 305 ? 121.284 166.697 127.705 1.00 92.17  ?  308 GLU C CD  1 
ATOM   1340 O OE1 . GLU A 1 305 ? 120.549 167.584 127.222 1.00 92.17  ?  308 GLU C OE1 1 
ATOM   1341 O OE2 . GLU A 1 305 ? 121.539 165.628 127.111 1.00 92.17  -1 308 GLU C OE2 1 
ATOM   1342 N N   . ASP A 1 306 ? 125.535 169.681 130.268 1.00 94.92  ?  309 ASP C N   1 
ATOM   1343 C CA  . ASP A 1 306 ? 126.869 170.250 130.113 1.00 94.92  ?  309 ASP C CA  1 
ATOM   1344 C C   . ASP A 1 306 ? 127.807 169.841 131.238 1.00 94.92  ?  309 ASP C C   1 
ATOM   1345 O O   . ASP A 1 306 ? 129.028 169.948 131.078 1.00 94.92  ?  309 ASP C O   1 
ATOM   1346 C CB  . ASP A 1 306 ? 126.795 171.776 130.029 1.00 94.92  ?  309 ASP C CB  1 
ATOM   1347 C CG  . ASP A 1 306 ? 126.056 172.257 128.797 1.00 94.92  ?  309 ASP C CG  1 
ATOM   1348 O OD1 . ASP A 1 306 ? 125.676 171.410 127.962 1.00 94.92  ?  309 ASP C OD1 1 
ATOM   1349 O OD2 . ASP A 1 306 ? 125.855 173.482 128.663 1.00 94.92  -1 309 ASP C OD2 1 
ATOM   1350 N N   . LEU A 1 307 ? 127.271 169.380 132.370 1.00 87.42  ?  310 LEU C N   1 
ATOM   1351 C CA  . LEU A 1 307 ? 128.122 168.850 133.426 1.00 87.42  ?  310 LEU C CA  1 
ATOM   1352 C C   . LEU A 1 307 ? 128.751 167.522 133.034 1.00 87.42  ?  310 LEU C C   1 
ATOM   1353 O O   . LEU A 1 307 ? 129.714 167.090 133.677 1.00 87.42  ?  310 LEU C O   1 
ATOM   1354 C CB  . LEU A 1 307 ? 127.319 168.687 134.717 1.00 87.42  ?  310 LEU C CB  1 
ATOM   1355 C CG  . LEU A 1 307 ? 126.663 169.956 135.260 1.00 87.42  ?  310 LEU C CG  1 
ATOM   1356 C CD1 . LEU A 1 307 ? 125.716 169.623 136.399 1.00 87.42  ?  310 LEU C CD1 1 
ATOM   1357 C CD2 . LEU A 1 307 ? 127.718 170.952 135.710 1.00 87.42  ?  310 LEU C CD2 1 
ATOM   1358 N N   . ASN A 1 308 ? 128.230 166.871 131.998 1.00 87.58  ?  311 ASN C N   1 
ATOM   1359 C CA  . ASN A 1 308 ? 128.766 165.608 131.497 1.00 87.58  ?  311 ASN C CA  1 
ATOM   1360 C C   . ASN A 1 308 ? 129.872 165.924 130.500 1.00 87.58  ?  311 ASN C C   1 
ATOM   1361 O O   . ASN A 1 308 ? 129.645 166.009 129.292 1.00 87.58  ?  311 ASN C O   1 
ATOM   1362 C CB  . ASN A 1 308 ? 127.660 164.776 130.861 1.00 87.58  ?  311 ASN C CB  1 
ATOM   1363 C CG  . ASN A 1 308 ? 128.190 163.565 130.119 1.00 87.58  ?  311 ASN C CG  1 
ATOM   1364 O OD1 . ASN A 1 308 ? 129.172 162.950 130.532 1.00 87.58  ?  311 ASN C OD1 1 
ATOM   1365 N ND2 . ASN A 1 308 ? 127.540 163.217 129.015 1.00 87.58  ?  311 ASN C ND2 1 
ATOM   1366 N N   . LYS A 1 309 ? 131.087 166.118 131.005 1.00 89.23  ?  312 LYS C N   1 
ATOM   1367 C CA  . LYS A 1 309 ? 132.223 166.372 130.119 1.00 89.23  ?  312 LYS C CA  1 
ATOM   1368 C C   . LYS A 1 309 ? 132.951 165.080 129.760 1.00 89.23  ?  312 LYS C C   1 
ATOM   1369 O O   . LYS A 1 309 ? 134.177 164.995 129.792 1.00 89.23  ?  312 LYS C O   1 
ATOM   1370 C CB  . LYS A 1 309 ? 133.168 167.372 130.773 1.00 89.23  ?  312 LYS C CB  1 
ATOM   1371 C CG  . LYS A 1 309 ? 133.522 167.032 132.213 1.00 89.23  ?  312 LYS C CG  1 
ATOM   1372 C CD  . LYS A 1 309 ? 134.218 168.193 132.903 1.00 89.23  ?  312 LYS C CD  1 
ATOM   1373 C CE  . LYS A 1 309 ? 133.227 169.281 133.282 1.00 89.23  ?  312 LYS C CE  1 
ATOM   1374 N NZ  . LYS A 1 309 ? 132.274 168.823 134.330 1.00 89.23  1  312 LYS C NZ  1 
ATOM   1375 N N   . ARG A 1 310 ? 132.179 164.057 129.411 1.00 89.96  ?  313 ARG C N   1 
ATOM   1376 C CA  . ARG A 1 310 ? 132.711 162.846 128.799 1.00 89.96  ?  313 ARG C CA  1 
ATOM   1377 C C   . ARG A 1 310 ? 131.717 162.333 127.756 1.00 89.96  ?  313 ARG C C   1 
ATOM   1378 O O   . ARG A 1 310 ? 131.446 161.135 127.651 1.00 89.96  ?  313 ARG C O   1 
ATOM   1379 C CB  . ARG A 1 310 ? 133.057 161.803 129.864 1.00 89.96  ?  313 ARG C CB  1 
ATOM   1380 C CG  . ARG A 1 310 ? 131.887 161.210 130.625 1.00 89.96  ?  313 ARG C CG  1 
ATOM   1381 C CD  . ARG A 1 310 ? 132.378 160.201 131.649 1.00 89.96  ?  313 ARG C CD  1 
ATOM   1382 N NE  . ARG A 1 310 ? 133.189 160.827 132.686 1.00 89.96  ?  313 ARG C NE  1 
ATOM   1383 C CZ  . ARG A 1 310 ? 134.502 160.679 132.800 1.00 89.96  ?  313 ARG C CZ  1 
ATOM   1384 N NH1 . ARG A 1 310 ? 135.189 159.930 131.954 1.00 89.96  1  313 ARG C NH1 1 
ATOM   1385 N NH2 . ARG A 1 310 ? 135.141 161.301 133.787 1.00 89.96  ?  313 ARG C NH2 1 
ATOM   1386 N N   . LYS A 1 311 ? 131.180 163.252 126.948 1.00 89.92  ?  314 LYS C N   1 
ATOM   1387 C CA  . LYS A 1 311 ? 130.062 162.936 126.064 1.00 89.92  ?  314 LYS C CA  1 
ATOM   1388 C C   . LYS A 1 311 ? 130.397 161.858 125.042 1.00 89.92  ?  314 LYS C C   1 
ATOM   1389 O O   . LYS A 1 311 ? 129.481 161.263 124.465 1.00 89.92  ?  314 LYS C O   1 
ATOM   1390 C CB  . LYS A 1 311 ? 129.597 164.201 125.341 1.00 89.92  ?  314 LYS C CB  1 
ATOM   1391 C CG  . LYS A 1 311 ? 128.702 165.101 126.174 1.00 89.92  ?  314 LYS C CG  1 
ATOM   1392 C CD  . LYS A 1 311 ? 128.435 166.419 125.468 1.00 89.92  ?  314 LYS C CD  1 
ATOM   1393 C CE  . LYS A 1 311 ? 129.499 167.451 125.802 1.00 89.92  ?  314 LYS C CE  1 
ATOM   1394 N NZ  . LYS A 1 311 ? 129.412 167.905 127.216 1.00 89.92  1  314 LYS C NZ  1 
ATOM   1395 N N   . ASP A 1 312 ? 131.680 161.592 124.804 1.00 91.86  ?  315 ASP C N   1 
ATOM   1396 C CA  . ASP A 1 312 ? 132.077 160.573 123.842 1.00 91.86  ?  315 ASP C CA  1 
ATOM   1397 C C   . ASP A 1 312 ? 131.917 159.150 124.364 1.00 91.86  ?  315 ASP C C   1 
ATOM   1398 O O   . ASP A 1 312 ? 132.076 158.205 123.585 1.00 91.86  ?  315 ASP C O   1 
ATOM   1399 C CB  . ASP A 1 312 ? 133.527 160.810 123.402 1.00 91.86  ?  315 ASP C CB  1 
ATOM   1400 C CG  . ASP A 1 312 ? 134.521 160.693 124.549 1.00 91.86  ?  315 ASP C CG  1 
ATOM   1401 O OD1 . ASP A 1 312 ? 134.099 160.470 125.703 1.00 91.86  ?  315 ASP C OD1 1 
ATOM   1402 O OD2 . ASP A 1 312 ? 135.735 160.827 124.291 1.00 91.86  -1 315 ASP C OD2 1 
ATOM   1403 N N   . THR A 1 313 ? 131.606 158.969 125.649 1.00 87.76  ?  316 THR C N   1 
ATOM   1404 C CA  . THR A 1 313 ? 131.520 157.640 126.237 1.00 87.76  ?  316 THR C CA  1 
ATOM   1405 C C   . THR A 1 313 ? 130.171 157.313 126.863 1.00 87.76  ?  316 THR C C   1 
ATOM   1406 O O   . THR A 1 313 ? 129.913 156.135 127.134 1.00 87.76  ?  316 THR C O   1 
ATOM   1407 C CB  . THR A 1 313 ? 132.612 157.453 127.303 1.00 87.76  ?  316 THR C CB  1 
ATOM   1408 O OG1 . THR A 1 313 ? 132.619 158.580 128.188 1.00 87.76  ?  316 THR C OG1 1 
ATOM   1409 C CG2 . THR A 1 313 ? 133.978 157.316 126.650 1.00 87.76  ?  316 THR C CG2 1 
ATOM   1410 N N   . LYS A 1 314 ? 129.309 158.299 127.100 1.00 81.29  ?  317 LYS C N   1 
ATOM   1411 C CA  . LYS A 1 314 ? 128.017 158.033 127.716 1.00 81.29  ?  317 LYS C CA  1 
ATOM   1412 C C   . LYS A 1 314 ? 127.004 159.059 127.230 1.00 81.29  ?  317 LYS C C   1 
ATOM   1413 O O   . LYS A 1 314 ? 127.362 160.125 126.724 1.00 81.29  ?  317 LYS C O   1 
ATOM   1414 C CB  . LYS A 1 314 ? 128.103 158.053 129.246 1.00 81.29  ?  317 LYS C CB  1 
ATOM   1415 C CG  . LYS A 1 314 ? 128.347 159.428 129.836 1.00 81.29  ?  317 LYS C CG  1 
ATOM   1416 C CD  . LYS A 1 314 ? 128.894 159.325 131.247 1.00 81.29  ?  317 LYS C CD  1 
ATOM   1417 C CE  . LYS A 1 314 ? 127.780 159.190 132.263 1.00 81.29  ?  317 LYS C CE  1 
ATOM   1418 N NZ  . LYS A 1 314 ? 128.309 158.834 133.607 1.00 81.29  1  317 LYS C NZ  1 
ATOM   1419 N N   . GLU A 1 315 ? 125.728 158.720 127.396 1.00 77.25  ?  318 GLU C N   1 
ATOM   1420 C CA  . GLU A 1 315 ? 124.620 159.555 126.959 1.00 77.25  ?  318 GLU C CA  1 
ATOM   1421 C C   . GLU A 1 315 ? 123.696 159.837 128.135 1.00 77.25  ?  318 GLU C C   1 
ATOM   1422 O O   . GLU A 1 315 ? 123.479 158.971 128.987 1.00 77.25  ?  318 GLU C O   1 
ATOM   1423 C CB  . GLU A 1 315 ? 123.838 158.882 125.826 1.00 77.25  ?  318 GLU C CB  1 
ATOM   1424 C CG  . GLU A 1 315 ? 122.758 159.753 125.206 1.00 77.25  ?  318 GLU C CG  1 
ATOM   1425 C CD  . GLU A 1 315 ? 122.096 159.098 124.011 1.00 77.25  ?  318 GLU C CD  1 
ATOM   1426 O OE1 . GLU A 1 315 ? 122.555 158.014 123.595 1.00 77.25  ?  318 GLU C OE1 1 
ATOM   1427 O OE2 . GLU A 1 315 ? 121.114 159.667 123.489 1.00 77.25  -1 318 GLU C OE2 1 
ATOM   1428 N N   . ILE A 1 316 ? 123.157 161.052 128.178 1.00 73.31  ?  319 ILE C N   1 
ATOM   1429 C CA  . ILE A 1 316 ? 122.238 161.480 129.225 1.00 73.31  ?  319 ILE C CA  1 
ATOM   1430 C C   . ILE A 1 316 ? 120.841 161.525 128.622 1.00 73.31  ?  319 ILE C C   1 
ATOM   1431 O O   . ILE A 1 316 ? 120.574 162.318 127.710 1.00 73.31  ?  319 ILE C O   1 
ATOM   1432 C CB  . ILE A 1 316 ? 122.630 162.844 129.809 1.00 73.31  ?  319 ILE C CB  1 
ATOM   1433 C CG1 . ILE A 1 316 ? 124.124 162.879 130.137 1.00 73.31  ?  319 ILE C CG1 1 
ATOM   1434 C CG2 . ILE A 1 316 ? 121.795 163.157 131.038 1.00 73.31  ?  319 ILE C CG2 1 
ATOM   1435 C CD1 . ILE A 1 316 ? 124.489 162.149 131.407 1.00 73.31  ?  319 ILE C CD1 1 
ATOM   1436 N N   . TYR A 1 317 ? 119.947 160.679 129.126 1.00 70.88  ?  320 TYR C N   1 
ATOM   1437 C CA  . TYR A 1 317 ? 118.556 160.660 128.688 1.00 70.88  ?  320 TYR C CA  1 
ATOM   1438 C C   . TYR A 1 317 ? 117.739 161.512 129.652 1.00 70.88  ?  320 TYR C C   1 
ATOM   1439 O O   . TYR A 1 317 ? 117.575 161.152 130.822 1.00 70.88  ?  320 TYR C O   1 
ATOM   1440 C CB  . TYR A 1 317 ? 118.022 159.232 128.631 1.00 70.88  ?  320 TYR C CB  1 
ATOM   1441 C CG  . TYR A 1 317 ? 118.883 158.276 127.838 1.00 70.88  ?  320 TYR C CG  1 
ATOM   1442 C CD1 . TYR A 1 317 ? 118.688 158.103 126.476 1.00 70.88  ?  320 TYR C CD1 1 
ATOM   1443 C CD2 . TYR A 1 317 ? 119.887 157.542 128.454 1.00 70.88  ?  320 TYR C CD2 1 
ATOM   1444 C CE1 . TYR A 1 317 ? 119.470 157.229 125.748 1.00 70.88  ?  320 TYR C CE1 1 
ATOM   1445 C CE2 . TYR A 1 317 ? 120.675 156.667 127.734 1.00 70.88  ?  320 TYR C CE2 1 
ATOM   1446 C CZ  . TYR A 1 317 ? 120.462 156.514 126.383 1.00 70.88  ?  320 TYR C CZ  1 
ATOM   1447 O OH  . TYR A 1 317 ? 121.245 155.642 125.663 1.00 70.88  ?  320 TYR C OH  1 
ATOM   1448 N N   . THR A 1 318 ? 117.223 162.636 129.164 1.00 75.78  ?  321 THR C N   1 
ATOM   1449 C CA  . THR A 1 318 ? 116.470 163.576 129.982 1.00 75.78  ?  321 THR C CA  1 
ATOM   1450 C C   . THR A 1 318 ? 114.988 163.463 129.658 1.00 75.78  ?  321 THR C C   1 
ATOM   1451 O O   . THR A 1 318 ? 114.598 163.513 128.487 1.00 75.78  ?  321 THR C O   1 
ATOM   1452 C CB  . THR A 1 318 ? 116.947 165.010 129.753 1.00 75.78  ?  321 THR C CB  1 
ATOM   1453 O OG1 . THR A 1 318 ? 118.372 165.068 129.886 1.00 75.78  ?  321 THR C OG1 1 
ATOM   1454 C CG2 . THR A 1 318 ? 116.312 165.947 130.767 1.00 75.78  ?  321 THR C CG2 1 
ATOM   1455 N N   . HIS A 1 319 ? 114.168 163.310 130.695 1.00 81.07  ?  322 HIS C N   1 
ATOM   1456 C CA  . HIS A 1 319 ? 112.724 163.207 130.547 1.00 81.07  ?  322 HIS C CA  1 
ATOM   1457 C C   . HIS A 1 319 ? 112.039 164.112 131.558 1.00 81.07  ?  322 HIS C C   1 
ATOM   1458 O O   . HIS A 1 319 ? 112.425 164.153 132.729 1.00 81.07  ?  322 HIS C O   1 
ATOM   1459 C CB  . HIS A 1 319 ? 112.244 161.765 130.734 1.00 81.07  ?  322 HIS C CB  1 
ATOM   1460 C CG  . HIS A 1 319 ? 110.789 161.571 130.441 1.00 81.07  ?  322 HIS C CG  1 
ATOM   1461 N ND1 . HIS A 1 319 ? 109.986 160.733 131.184 1.00 81.07  ?  322 HIS C ND1 1 
ATOM   1462 C CD2 . HIS A 1 319 ? 109.993 162.107 129.486 1.00 81.07  ?  322 HIS C CD2 1 
ATOM   1463 C CE1 . HIS A 1 319 ? 108.757 160.761 130.699 1.00 81.07  ?  322 HIS C CE1 1 
ATOM   1464 N NE2 . HIS A 1 319 ? 108.734 161.587 129.669 1.00 81.07  ?  322 HIS C NE2 1 
ATOM   1465 N N   . PHE A 1 320 ? 111.021 164.833 131.099 1.00 88.42  ?  323 PHE C N   1 
ATOM   1466 C CA  . PHE A 1 320 ? 110.199 165.662 131.970 1.00 88.42  ?  323 PHE C CA  1 
ATOM   1467 C C   . PHE A 1 320 ? 108.995 164.852 132.429 1.00 88.42  ?  323 PHE C C   1 
ATOM   1468 O O   . PHE A 1 320 ? 108.234 164.339 131.602 1.00 88.42  ?  323 PHE C O   1 
ATOM   1469 C CB  . PHE A 1 320 ? 109.751 166.931 131.250 1.00 88.42  ?  323 PHE C CB  1 
ATOM   1470 C CG  . PHE A 1 320 ? 110.830 167.959 131.110 1.00 88.42  ?  323 PHE C CG  1 
ATOM   1471 C CD1 . PHE A 1 320 ? 111.764 167.870 130.094 1.00 88.42  ?  323 PHE C CD1 1 
ATOM   1472 C CD2 . PHE A 1 320 ? 110.910 169.017 131.997 1.00 88.42  ?  323 PHE C CD2 1 
ATOM   1473 C CE1 . PHE A 1 320 ? 112.757 168.817 129.967 1.00 88.42  ?  323 PHE C CE1 1 
ATOM   1474 C CE2 . PHE A 1 320 ? 111.900 169.966 131.874 1.00 88.42  ?  323 PHE C CE2 1 
ATOM   1475 C CZ  . PHE A 1 320 ? 112.824 169.865 130.858 1.00 88.42  ?  323 PHE C CZ  1 
ATOM   1476 N N   . THR A 1 321 ? 108.822 164.738 133.742 1.00 94.17  ?  324 THR C N   1 
ATOM   1477 C CA  . THR A 1 321 ? 107.769 163.916 134.314 1.00 94.17  ?  324 THR C CA  1 
ATOM   1478 C C   . THR A 1 321 ? 107.077 164.657 135.449 1.00 94.17  ?  324 THR C C   1 
ATOM   1479 O O   . THR A 1 321 ? 107.614 165.607 136.023 1.00 94.17  ?  324 THR C O   1 
ATOM   1480 C CB  . THR A 1 321 ? 108.315 162.578 134.823 1.00 94.17  ?  324 THR C CB  1 
ATOM   1481 O OG1 . THR A 1 321 ? 107.247 161.811 135.391 1.00 94.17  ?  324 THR C OG1 1 
ATOM   1482 C CG2 . THR A 1 321 ? 109.388 162.803 135.865 1.00 94.17  ?  324 THR C CG2 1 
ATOM   1483 N N   . CYS A 1 322 ? 105.869 164.199 135.766 1.00 105.61 ?  325 CYS C N   1 
ATOM   1484 C CA  . CYS A 1 322 ? 105.052 164.788 136.819 1.00 105.61 ?  325 CYS C CA  1 
ATOM   1485 C C   . CYS A 1 322 ? 104.482 163.656 137.667 1.00 105.61 ?  325 CYS C C   1 
ATOM   1486 O O   . CYS A 1 322 ? 104.886 162.495 137.542 1.00 105.61 ?  325 CYS C O   1 
ATOM   1487 C CB  . CYS A 1 322 ? 103.955 165.680 136.223 1.00 105.61 ?  325 CYS C CB  1 
ATOM   1488 S SG  . CYS A 1 322 ? 103.041 166.652 137.443 1.00 105.61 ?  325 CYS C SG  1 
ATOM   1489 N N   . SER A 1 323 ? 103.536 164.000 138.543 1.00 109.16 ?  326 SER C N   1 
ATOM   1490 C CA  . SER A 1 323 ? 102.981 163.020 139.472 1.00 109.16 ?  326 SER C CA  1 
ATOM   1491 C C   . SER A 1 323 ? 102.214 161.926 138.736 1.00 109.16 ?  326 SER C C   1 
ATOM   1492 O O   . SER A 1 323 ? 102.366 160.735 139.031 1.00 109.16 ?  326 SER C O   1 
ATOM   1493 C CB  . SER A 1 323 ? 102.083 163.720 140.492 1.00 109.16 ?  326 SER C CB  1 
ATOM   1494 N N   . THR A 1 324 ? 101.382 162.312 137.772 1.00 108.24 ?  327 THR C N   1 
ATOM   1495 C CA  . THR A 1 324 ? 100.513 161.379 137.055 1.00 108.24 ?  327 THR C CA  1 
ATOM   1496 C C   . THR A 1 324 ? 100.880 161.413 135.573 1.00 108.24 ?  327 THR C C   1 
ATOM   1497 O O   . THR A 1 324 ? 100.307 162.175 134.792 1.00 108.24 ?  327 THR C O   1 
ATOM   1498 C CB  . THR A 1 324 ? 99.041  161.727 137.271 1.00 108.24 ?  327 THR C CB  1 
ATOM   1499 N N   . ASP A 1 325 ? 101.845 160.580 135.191 1.00 103.66 ?  328 ASP C N   1 
ATOM   1500 C CA  . ASP A 1 325 ? 102.270 160.460 133.802 1.00 103.66 ?  328 ASP C CA  1 
ATOM   1501 C C   . ASP A 1 325 ? 102.065 159.061 133.244 1.00 103.66 ?  328 ASP C C   1 
ATOM   1502 O O   . ASP A 1 325 ? 101.513 158.913 132.147 1.00 103.66 ?  328 ASP C O   1 
ATOM   1503 C CB  . ASP A 1 325 ? 103.743 160.873 133.667 1.00 103.66 ?  328 ASP C CB  1 
ATOM   1504 C CG  . ASP A 1 325 ? 103.906 162.356 133.411 1.00 103.66 ?  328 ASP C CG  1 
ATOM   1505 O OD1 . ASP A 1 325 ? 103.145 162.907 132.588 1.00 103.66 ?  328 ASP C OD1 1 
ATOM   1506 O OD2 . ASP A 1 325 ? 104.787 162.974 134.040 1.00 103.66 -1 328 ASP C OD2 1 
ATOM   1507 N N   . THR A 1 326 ? 102.512 158.031 133.964 1.00 99.50  ?  329 THR C N   1 
ATOM   1508 C CA  . THR A 1 326 ? 102.440 156.624 133.573 1.00 99.50  ?  329 THR C CA  1 
ATOM   1509 C C   . THR A 1 326 ? 103.244 156.316 132.314 1.00 99.50  ?  329 THR C C   1 
ATOM   1510 O O   . THR A 1 326 ? 103.123 155.215 131.762 1.00 99.50  ?  329 THR C O   1 
ATOM   1511 C CB  . THR A 1 326 ? 100.989 156.151 133.388 1.00 99.50  ?  329 THR C CB  1 
ATOM   1512 O OG1 . THR A 1 326 ? 100.404 156.806 132.256 1.00 99.50  ?  329 THR C OG1 1 
ATOM   1513 C CG2 . THR A 1 326 ? 100.165 156.458 134.630 1.00 99.50  ?  329 THR C CG2 1 
ATOM   1514 N N   . LYS A 1 327 ? 104.063 157.256 131.845 1.00 92.22  ?  330 LYS C N   1 
ATOM   1515 C CA  . LYS A 1 327 ? 104.939 157.033 130.705 1.00 92.22  ?  330 LYS C CA  1 
ATOM   1516 C C   . LYS A 1 327 ? 106.404 156.907 131.097 1.00 92.22  ?  330 LYS C C   1 
ATOM   1517 O O   . LYS A 1 327 ? 107.242 156.649 130.226 1.00 92.22  ?  330 LYS C O   1 
ATOM   1518 C CB  . LYS A 1 327 ? 104.787 158.170 129.688 1.00 92.22  ?  330 LYS C CB  1 
ATOM   1519 C CG  . LYS A 1 327 ? 103.423 158.239 129.028 1.00 92.22  ?  330 LYS C CG  1 
ATOM   1520 C CD  . LYS A 1 327 ? 103.358 159.380 128.027 1.00 92.22  ?  330 LYS C CD  1 
ATOM   1521 C CE  . LYS A 1 327 ? 102.026 159.399 127.297 1.00 92.22  ?  330 LYS C CE  1 
ATOM   1522 N NZ  . LYS A 1 327 ? 100.897 159.728 128.211 1.00 92.22  1  330 LYS C NZ  1 
ATOM   1523 N N   . ASN A 1 328 ? 106.731 157.085 132.379 1.00 85.59  ?  331 ASN C N   1 
ATOM   1524 C CA  . ASN A 1 328 ? 108.128 157.071 132.800 1.00 85.59  ?  331 ASN C CA  1 
ATOM   1525 C C   . ASN A 1 328 ? 108.732 155.680 132.677 1.00 85.59  ?  331 ASN C C   1 
ATOM   1526 O O   . ASN A 1 328 ? 109.917 155.536 132.352 1.00 85.59  ?  331 ASN C O   1 
ATOM   1527 C CB  . ASN A 1 328 ? 108.242 157.584 134.232 1.00 85.59  ?  331 ASN C CB  1 
ATOM   1528 C CG  . ASN A 1 328 ? 107.688 158.979 134.387 1.00 85.59  ?  331 ASN C CG  1 
ATOM   1529 O OD1 . ASN A 1 328 ? 107.748 159.784 133.460 1.00 85.59  ?  331 ASN C OD1 1 
ATOM   1530 N ND2 . ASN A 1 328 ? 107.143 159.275 135.559 1.00 85.59  ?  331 ASN C ND2 1 
ATOM   1531 N N   . VAL A 1 329 ? 107.938 154.642 132.946 1.00 79.95  ?  332 VAL C N   1 
ATOM   1532 C CA  . VAL A 1 329 ? 108.441 153.278 132.817 1.00 79.95  ?  332 VAL C CA  1 
ATOM   1533 C C   . VAL A 1 329 ? 108.817 152.989 131.371 1.00 79.95  ?  332 VAL C C   1 
ATOM   1534 O O   . VAL A 1 329 ? 109.820 152.320 131.097 1.00 79.95  ?  332 VAL C O   1 
ATOM   1535 C CB  . VAL A 1 329 ? 107.404 152.272 133.347 1.00 79.95  ?  332 VAL C CB  1 
ATOM   1536 C CG1 . VAL A 1 329 ? 108.021 150.890 133.460 1.00 79.95  ?  332 VAL C CG1 1 
ATOM   1537 C CG2 . VAL A 1 329 ? 106.859 152.731 134.688 1.00 79.95  ?  332 VAL C CG2 1 
ATOM   1538 N N   . GLN A 1 330 ? 108.027 153.497 130.422 1.00 79.60  ?  333 GLN C N   1 
ATOM   1539 C CA  . GLN A 1 330 ? 108.354 153.311 129.012 1.00 79.60  ?  333 GLN C CA  1 
ATOM   1540 C C   . GLN A 1 330 ? 109.646 154.030 128.642 1.00 79.60  ?  333 GLN C C   1 
ATOM   1541 O O   . GLN A 1 330 ? 110.459 153.504 127.874 1.00 79.60  ?  333 GLN C O   1 
ATOM   1542 C CB  . GLN A 1 330 ? 107.197 153.794 128.138 1.00 79.60  ?  333 GLN C CB  1 
ATOM   1543 C CG  . GLN A 1 330 ? 107.483 153.734 126.650 1.00 79.60  ?  333 GLN C CG  1 
ATOM   1544 C CD  . GLN A 1 330 ? 107.503 152.314 126.123 1.00 79.60  ?  333 GLN C CD  1 
ATOM   1545 O OE1 . GLN A 1 330 ? 106.693 151.479 126.525 1.00 79.60  ?  333 GLN C OE1 1 
ATOM   1546 N NE2 . GLN A 1 330 ? 108.432 152.031 125.218 1.00 79.60  ?  333 GLN C NE2 1 
ATOM   1547 N N   . PHE A 1 331 ? 109.848 155.240 129.170 1.00 75.65  ?  334 PHE C N   1 
ATOM   1548 C CA  . PHE A 1 331 ? 111.089 155.964 128.905 1.00 75.65  ?  334 PHE C CA  1 
ATOM   1549 C C   . PHE A 1 331 ? 112.290 155.221 129.476 1.00 75.65  ?  334 PHE C C   1 
ATOM   1550 O O   . PHE A 1 331 ? 113.340 155.123 128.826 1.00 75.65  ?  334 PHE C O   1 
ATOM   1551 C CB  . PHE A 1 331 ? 111.004 157.376 129.484 1.00 75.65  ?  334 PHE C CB  1 
ATOM   1552 C CG  . PHE A 1 331 ? 112.162 158.255 129.111 1.00 75.65  ?  334 PHE C CG  1 
ATOM   1553 C CD1 . PHE A 1 331 ? 112.131 159.006 127.950 1.00 75.65  ?  334 PHE C CD1 1 
ATOM   1554 C CD2 . PHE A 1 331 ? 113.280 158.333 129.923 1.00 75.65  ?  334 PHE C CD2 1 
ATOM   1555 C CE1 . PHE A 1 331 ? 113.193 159.815 127.604 1.00 75.65  ?  334 PHE C CE1 1 
ATOM   1556 C CE2 . PHE A 1 331 ? 114.346 159.140 129.581 1.00 75.65  ?  334 PHE C CE2 1 
ATOM   1557 C CZ  . PHE A 1 331 ? 114.302 159.882 128.421 1.00 75.65  ?  334 PHE C CZ  1 
ATOM   1558 N N   . VAL A 1 332 ? 112.154 154.693 130.694 1.00 72.96  ?  335 VAL C N   1 
ATOM   1559 C CA  . VAL A 1 332 ? 113.232 153.909 131.290 1.00 72.96  ?  335 VAL C CA  1 
ATOM   1560 C C   . VAL A 1 332 ? 113.509 152.672 130.449 1.00 72.96  ?  335 VAL C C   1 
ATOM   1561 O O   . VAL A 1 332 ? 114.667 152.306 130.222 1.00 72.96  ?  335 VAL C O   1 
ATOM   1562 C CB  . VAL A 1 332 ? 112.887 153.542 132.745 1.00 72.96  ?  335 VAL C CB  1 
ATOM   1563 C CG1 . VAL A 1 332 ? 113.882 152.533 133.291 1.00 72.96  ?  335 VAL C CG1 1 
ATOM   1564 C CG2 . VAL A 1 332 ? 112.865 154.785 133.611 1.00 72.96  ?  335 VAL C CG2 1 
ATOM   1565 N N   . PHE A 1 333 ? 112.452 152.014 129.969 1.00 75.43  ?  336 PHE C N   1 
ATOM   1566 C CA  . PHE A 1 333 ? 112.629 150.835 129.129 1.00 75.43  ?  336 PHE C CA  1 
ATOM   1567 C C   . PHE A 1 333 ? 113.362 151.179 127.840 1.00 75.43  ?  336 PHE C C   1 
ATOM   1568 O O   . PHE A 1 333 ? 114.246 150.436 127.407 1.00 75.43  ?  336 PHE C O   1 
ATOM   1569 C CB  . PHE A 1 333 ? 111.273 150.201 128.823 1.00 75.43  ?  336 PHE C CB  1 
ATOM   1570 C CG  . PHE A 1 333 ? 111.362 148.953 127.996 1.00 75.43  ?  336 PHE C CG  1 
ATOM   1571 C CD1 . PHE A 1 333 ? 111.780 147.761 128.561 1.00 75.43  ?  336 PHE C CD1 1 
ATOM   1572 C CD2 . PHE A 1 333 ? 111.028 148.970 126.654 1.00 75.43  ?  336 PHE C CD2 1 
ATOM   1573 C CE1 . PHE A 1 333 ? 111.864 146.611 127.803 1.00 75.43  ?  336 PHE C CE1 1 
ATOM   1574 C CE2 . PHE A 1 333 ? 111.110 147.824 125.891 1.00 75.43  ?  336 PHE C CE2 1 
ATOM   1575 C CZ  . PHE A 1 333 ? 111.528 146.643 126.467 1.00 75.43  ?  336 PHE C CZ  1 
ATOM   1576 N N   . ASP A 1 334 ? 113.009 152.302 127.211 1.00 76.44  ?  337 ASP C N   1 
ATOM   1577 C CA  . ASP A 1 334 ? 113.688 152.706 125.983 1.00 76.44  ?  337 ASP C CA  1 
ATOM   1578 C C   . ASP A 1 334 ? 115.160 153.012 126.235 1.00 76.44  ?  337 ASP C C   1 
ATOM   1579 O O   . ASP A 1 334 ? 116.032 152.605 125.453 1.00 76.44  ?  337 ASP C O   1 
ATOM   1580 C CB  . ASP A 1 334 ? 112.987 153.918 125.370 1.00 76.44  ?  337 ASP C CB  1 
ATOM   1581 C CG  . ASP A 1 334 ? 111.573 153.609 124.925 1.00 76.44  ?  337 ASP C CG  1 
ATOM   1582 O OD1 . ASP A 1 334 ? 111.178 152.426 124.977 1.00 76.44  ?  337 ASP C OD1 1 
ATOM   1583 O OD2 . ASP A 1 334 ? 110.856 154.549 124.525 1.00 76.44  -1 337 ASP C OD2 1 
ATOM   1584 N N   . ALA A 1 335 ? 115.458 153.722 127.326 1.00 72.64  ?  338 ALA C N   1 
ATOM   1585 C CA  . ALA A 1 335 ? 116.849 154.019 127.650 1.00 72.64  ?  338 ALA C CA  1 
ATOM   1586 C C   . ALA A 1 335 ? 117.636 152.742 127.919 1.00 72.64  ?  338 ALA C C   1 
ATOM   1587 O O   . ALA A 1 335 ? 118.785 152.605 127.481 1.00 72.64  ?  338 ALA C O   1 
ATOM   1588 C CB  . ALA A 1 335 ? 116.920 154.961 128.850 1.00 72.64  ?  338 ALA C CB  1 
ATOM   1589 N N   . VAL A 1 336 ? 117.031 151.791 128.633 1.00 72.82  ?  339 VAL C N   1 
ATOM   1590 C CA  . VAL A 1 336 ? 117.708 150.530 128.913 1.00 72.82  ?  339 VAL C CA  1 
ATOM   1591 C C   . VAL A 1 336 ? 117.909 149.728 127.634 1.00 72.82  ?  339 VAL C C   1 
ATOM   1592 O O   . VAL A 1 336 ? 118.930 149.055 127.469 1.00 72.82  ?  339 VAL C O   1 
ATOM   1593 C CB  . VAL A 1 336 ? 116.936 149.730 129.977 1.00 72.82  ?  339 VAL C CB  1 
ATOM   1594 C CG1 . VAL A 1 336 ? 117.577 148.377 130.184 1.00 72.82  ?  339 VAL C CG1 1 
ATOM   1595 C CG2 . VAL A 1 336 ? 116.926 150.486 131.290 1.00 72.82  ?  339 VAL C CG2 1 
ATOM   1596 N N   . THR A 1 337 ? 116.947 149.779 126.708 1.00 75.52  ?  340 THR C N   1 
ATOM   1597 C CA  . THR A 1 337 ? 117.135 149.098 125.430 1.00 75.52  ?  340 THR C CA  1 
ATOM   1598 C C   . THR A 1 337 ? 118.311 149.689 124.669 1.00 75.52  ?  340 THR C C   1 
ATOM   1599 O O   . THR A 1 337 ? 119.124 148.953 124.101 1.00 75.52  ?  340 THR C O   1 
ATOM   1600 C CB  . THR A 1 337 ? 115.869 149.177 124.575 1.00 75.52  ?  340 THR C CB  1 
ATOM   1601 O OG1 . THR A 1 337 ? 115.443 150.539 124.469 1.00 75.52  ?  340 THR C OG1 1 
ATOM   1602 C CG2 . THR A 1 337 ? 114.757 148.341 125.176 1.00 75.52  ?  340 THR C CG2 1 
ATOM   1603 N N   . ASP A 1 338 ? 118.418 151.020 124.647 1.00 76.13  ?  341 ASP C N   1 
ATOM   1604 C CA  . ASP A 1 338 ? 119.557 151.649 123.984 1.00 76.13  ?  341 ASP C CA  1 
ATOM   1605 C C   . ASP A 1 338 ? 120.872 151.249 124.647 1.00 76.13  ?  341 ASP C C   1 
ATOM   1606 O O   . ASP A 1 338 ? 121.854 150.931 123.962 1.00 76.13  ?  341 ASP C O   1 
ATOM   1607 C CB  . ASP A 1 338 ? 119.395 153.168 123.987 1.00 76.13  ?  341 ASP C CB  1 
ATOM   1608 C CG  . ASP A 1 338 ? 118.457 153.654 122.902 1.00 76.13  ?  341 ASP C CG  1 
ATOM   1609 O OD1 . ASP A 1 338 ? 117.485 152.935 122.590 1.00 76.13  ?  341 ASP C OD1 1 
ATOM   1610 O OD2 . ASP A 1 338 ? 118.692 154.754 122.361 1.00 76.13  -1 341 ASP C OD2 1 
ATOM   1611 N N   . VAL A 1 339 ? 120.903 151.246 125.981 1.00 74.75  ?  342 VAL C N   1 
ATOM   1612 C CA  . VAL A 1 339 ? 122.122 150.885 126.702 1.00 74.75  ?  342 VAL C CA  1 
ATOM   1613 C C   . VAL A 1 339 ? 122.507 149.439 126.418 1.00 74.75  ?  342 VAL C C   1 
ATOM   1614 O O   . VAL A 1 339 ? 123.684 149.123 126.210 1.00 74.75  ?  342 VAL C O   1 
ATOM   1615 C CB  . VAL A 1 339 ? 121.943 151.140 128.210 1.00 74.75  ?  342 VAL C CB  1 
ATOM   1616 C CG1 . VAL A 1 339 ? 123.089 150.525 128.996 1.00 74.75  ?  342 VAL C CG1 1 
ATOM   1617 C CG2 . VAL A 1 339 ? 121.845 152.628 128.485 1.00 74.75  ?  342 VAL C CG2 1 
ATOM   1618 N N   . ILE A 1 340 ? 121.525 148.537 126.409 1.00 76.56  ?  343 ILE C N   1 
ATOM   1619 C CA  . ILE A 1 340 ? 121.804 147.124 126.180 1.00 76.56  ?  343 ILE C CA  1 
ATOM   1620 C C   . ILE A 1 340 ? 122.254 146.889 124.744 1.00 76.56  ?  343 ILE C C   1 
ATOM   1621 O O   . ILE A 1 340 ? 123.126 146.054 124.485 1.00 76.56  ?  343 ILE C O   1 
ATOM   1622 C CB  . ILE A 1 340 ? 120.573 146.275 126.547 1.00 76.56  ?  343 ILE C CB  1 
ATOM   1623 C CG1 . ILE A 1 340 ? 120.376 146.265 128.063 1.00 76.56  ?  343 ILE C CG1 1 
ATOM   1624 C CG2 . ILE A 1 340 ? 120.720 144.854 126.034 1.00 76.56  ?  343 ILE C CG2 1 
ATOM   1625 C CD1 . ILE A 1 340 ? 119.181 145.465 128.518 1.00 76.56  ?  343 ILE C CD1 1 
ATOM   1626 N N   . ILE A 1 341 ? 121.672 147.615 123.787 1.00 77.17  ?  344 ILE C N   1 
ATOM   1627 C CA  . ILE A 1 341 ? 122.130 147.514 122.404 1.00 77.17  ?  344 ILE C CA  1 
ATOM   1628 C C   . ILE A 1 341 ? 123.580 147.967 122.292 1.00 77.17  ?  344 ILE C C   1 
ATOM   1629 O O   . ILE A 1 341 ? 124.401 147.318 121.628 1.00 77.17  ?  344 ILE C O   1 
ATOM   1630 C CB  . ILE A 1 341 ? 121.207 148.321 121.473 1.00 77.17  ?  344 ILE C CB  1 
ATOM   1631 C CG1 . ILE A 1 341 ? 119.881 147.588 121.271 1.00 77.17  ?  344 ILE C CG1 1 
ATOM   1632 C CG2 . ILE A 1 341 ? 121.878 148.569 120.135 1.00 77.17  ?  344 ILE C CG2 1 
ATOM   1633 C CD1 . ILE A 1 341 ? 118.902 148.336 120.398 1.00 77.17  ?  344 ILE C CD1 1 
ATOM   1634 N N   . LYS A 1 342 ? 123.920 149.082 122.944 1.00 85.40  ?  345 LYS C N   1 
ATOM   1635 C CA  . LYS A 1 342 ? 125.305 149.545 122.937 1.00 85.40  ?  345 LYS C CA  1 
ATOM   1636 C C   . LYS A 1 342 ? 126.236 148.516 123.568 1.00 85.40  ?  345 LYS C C   1 
ATOM   1637 O O   . LYS A 1 342 ? 127.330 148.257 123.053 1.00 85.40  ?  345 LYS C O   1 
ATOM   1638 C CB  . LYS A 1 342 ? 125.419 150.881 123.670 1.00 85.40  ?  345 LYS C CB  1 
ATOM   1639 C CG  . LYS A 1 342 ? 125.012 152.094 122.852 1.00 85.40  ?  345 LYS C CG  1 
ATOM   1640 C CD  . LYS A 1 342 ? 125.354 153.376 123.597 1.00 85.40  ?  345 LYS C CD  1 
ATOM   1641 C CE  . LYS A 1 342 ? 124.350 154.480 123.313 1.00 85.40  ?  345 LYS C CE  1 
ATOM   1642 N NZ  . LYS A 1 342 ? 123.848 154.431 121.915 1.00 85.40  1  345 LYS C NZ  1 
ATOM   1643 N N   . ASN A 1 343 ? 125.822 147.928 124.672 1.00 84.44  ?  346 ASN C N   1 
ATOM   1644 C CA  . ASN A 1 343 ? 126.684 146.991 125.361 1.00 84.44  ?  346 ASN C CA  1 
ATOM   1645 C C   . ASN A 1 343 ? 126.791 145.711 124.576 1.00 84.44  ?  346 ASN C C   1 
ATOM   1646 O O   . ASN A 1 343 ? 127.857 145.112 124.512 1.00 84.44  ?  346 ASN C O   1 
ATOM   1647 C CB  . ASN A 1 343 ? 126.155 146.703 126.756 1.00 84.44  ?  346 ASN C CB  1 
ATOM   1648 C CG  . ASN A 1 343 ? 126.141 147.930 127.636 1.00 84.44  ?  346 ASN C CG  1 
ATOM   1649 O OD1 . ASN A 1 343 ? 126.664 148.978 127.266 1.00 84.44  ?  346 ASN C OD1 1 
ATOM   1650 N ND2 . ASN A 1 343 ? 125.538 147.807 128.810 1.00 84.44  ?  346 ASN C ND2 1 
ATOM   1651 N N   . ASN A 1 344 ? 125.695 145.283 123.968 1.00 84.62  ?  347 ASN C N   1 
ATOM   1652 C CA  . ASN A 1 344 ? 125.725 144.082 123.155 1.00 84.62  ?  347 ASN C CA  1 
ATOM   1653 C C   . ASN A 1 344 ? 126.726 144.285 122.033 1.00 84.62  ?  347 ASN C C   1 
ATOM   1654 O O   . ASN A 1 344 ? 127.587 143.448 121.814 1.00 84.62  ?  347 ASN C O   1 
ATOM   1655 C CB  . ASN A 1 344 ? 124.343 143.757 122.610 1.00 84.62  ?  347 ASN C CB  1 
ATOM   1656 C CG  . ASN A 1 344 ? 123.493 142.993 123.595 1.00 84.62  ?  347 ASN C CG  1 
ATOM   1657 O OD1 . ASN A 1 344 ? 123.966 142.582 124.648 1.00 84.62  ?  347 ASN C OD1 1 
ATOM   1658 N ND2 . ASN A 1 344 ? 122.228 142.799 123.255 1.00 84.62  ?  347 ASN C ND2 1 
ATOM   1659 N N   . LEU A 1 345 ? 126.640 145.406 121.336 1.00 88.74  ?  348 LEU C N   1 
ATOM   1660 C CA  . LEU A 1 345 ? 127.568 145.692 120.261 1.00 88.74  ?  348 LEU C CA  1 
ATOM   1661 C C   . LEU A 1 345 ? 128.999 145.724 120.773 1.00 88.74  ?  348 LEU C C   1 
ATOM   1662 O O   . LEU A 1 345 ? 129.848 145.021 120.252 1.00 88.74  ?  348 LEU C O   1 
ATOM   1663 C CB  . LEU A 1 345 ? 127.208 147.002 119.579 1.00 88.74  ?  348 LEU C CB  1 
ATOM   1664 C CG  . LEU A 1 345 ? 125.933 146.986 118.747 1.00 88.74  ?  348 LEU C CG  1 
ATOM   1665 C CD1 . LEU A 1 345 ? 125.721 148.334 118.083 1.00 88.74  ?  348 LEU C CD1 1 
ATOM   1666 C CD2 . LEU A 1 345 ? 126.010 145.884 117.709 1.00 88.74  ?  348 LEU C CD2 1 
ATOM   1667 N N   . LYS A 1 346 ? 129.291 146.520 121.789 1.00 94.56  ?  349 LYS C N   1 
ATOM   1668 C CA  . LYS A 1 346 ? 130.636 146.514 122.354 1.00 94.56  ?  349 LYS C CA  1 
ATOM   1669 C C   . LYS A 1 346 ? 131.136 145.090 122.566 1.00 94.56  ?  349 LYS C C   1 
ATOM   1670 O O   . LYS A 1 346 ? 132.316 144.798 122.339 1.00 94.56  ?  349 LYS C O   1 
ATOM   1671 C CB  . LYS A 1 346 ? 130.653 147.294 123.669 1.00 94.56  ?  349 LYS C CB  1 
ATOM   1672 C CG  . LYS A 1 346 ? 132.020 147.382 124.325 1.00 94.56  ?  349 LYS C CG  1 
ATOM   1673 C CD  . LYS A 1 346 ? 131.986 148.289 125.543 1.00 94.56  ?  349 LYS C CD  1 
ATOM   1674 C CE  . LYS A 1 346 ? 131.234 147.640 126.693 1.00 94.56  ?  349 LYS C CE  1 
ATOM   1675 N NZ  . LYS A 1 346 ? 131.967 146.465 127.242 1.00 94.56  1  349 LYS C NZ  1 
ATOM   1676 N N   . ASP A 1 347 ? 130.252 144.193 123.009 1.00 98.99  ?  350 ASP C N   1 
ATOM   1677 C CA  . ASP A 1 347 ? 130.638 142.800 123.210 1.00 98.99  ?  350 ASP C CA  1 
ATOM   1678 C C   . ASP A 1 347 ? 131.055 142.148 121.898 1.00 98.99  ?  350 ASP C C   1 
ATOM   1679 O O   . ASP A 1 347 ? 132.051 141.416 121.848 1.00 98.99  ?  350 ASP C O   1 
ATOM   1680 C CB  . ASP A 1 347 ? 129.488 142.024 123.850 1.00 98.99  ?  350 ASP C CB  1 
ATOM   1681 C CG  . ASP A 1 347 ? 129.583 141.983 125.361 1.00 98.99  ?  350 ASP C CG  1 
ATOM   1682 O OD1 . ASP A 1 347 ? 130.332 142.803 125.933 1.00 98.99  ?  350 ASP C OD1 1 
ATOM   1683 O OD2 . ASP A 1 347 ? 128.908 141.133 125.978 1.00 98.99  -1 350 ASP C OD2 1 
ATOM   1684 N N   . CYS A 1 348 ? 130.304 142.397 120.823 1.00 101.85 ?  351 CYS C N   1 
ATOM   1685 C CA  . CYS A 1 348 ? 130.710 141.900 119.513 1.00 101.85 ?  351 CYS C CA  1 
ATOM   1686 C C   . CYS A 1 348 ? 131.965 142.586 118.994 1.00 101.85 ?  351 CYS C C   1 
ATOM   1687 O O   . CYS A 1 348 ? 132.610 142.059 118.081 1.00 101.85 ?  351 CYS C O   1 
ATOM   1688 C CB  . CYS A 1 348 ? 129.584 142.075 118.494 1.00 101.85 ?  351 CYS C CB  1 
ATOM   1689 S SG  . CYS A 1 348 ? 128.184 140.972 118.722 1.00 101.85 ?  351 CYS C SG  1 
ATOM   1690 N N   . GLY A 1 349 ? 132.325 143.740 119.548 1.00 106.30 ?  352 GLY C N   1 
ATOM   1691 C CA  . GLY A 1 349 ? 133.397 144.536 119.000 1.00 106.30 ?  352 GLY C CA  1 
ATOM   1692 C C   . GLY A 1 349 ? 133.006 145.372 117.804 1.00 106.30 ?  352 GLY C C   1 
ATOM   1693 O O   . GLY A 1 349 ? 133.874 146.031 117.218 1.00 106.30 ?  352 GLY C O   1 
ATOM   1694 N N   . LEU A 1 350 ? 131.734 145.365 117.423 1.00 101.23 ?  353 LEU C N   1 
ATOM   1695 C CA  . LEU A 1 350 ? 131.257 146.135 116.284 1.00 101.23 ?  353 LEU C CA  1 
ATOM   1696 C C   . LEU A 1 350 ? 131.183 147.617 116.633 1.00 101.23 ?  353 LEU C C   1 
ATOM   1697 O O   . LEU A 1 350 ? 131.149 148.475 115.751 1.00 101.23 ?  353 LEU C O   1 
ATOM   1698 C CB  . LEU A 1 350 ? 129.887 145.621 115.837 1.00 101.23 ?  353 LEU C CB  1 
ATOM   1699 C CG  . LEU A 1 350 ? 129.354 146.103 114.488 1.00 101.23 ?  353 LEU C CG  1 
ATOM   1700 C CD1 . LEU A 1 350 ? 130.451 146.082 113.437 1.00 101.23 ?  353 LEU C CD1 1 
ATOM   1701 C CD2 . LEU A 1 350 ? 128.170 145.257 114.053 1.00 101.23 ?  353 LEU C CD2 1 
ATOM   1702 N N   . PHE A 1 351 ? 131.160 147.911 117.929 1.00 101.65 ?  354 PHE C N   1 
ATOM   1703 C CA  . PHE A 1 351 ? 131.103 149.288 118.403 1.00 101.65 ?  354 PHE C CA  1 
ATOM   1704 C CB  . PHE A 1 351 ? 130.823 149.323 119.907 1.00 101.65 ?  354 PHE C CB  1 
ATOM   1705 C CG  . PHE A 1 351 ? 129.924 150.448 120.329 1.00 101.65 ?  354 PHE C CG  1 
ATOM   1706 C CD1 . PHE A 1 351 ? 128.927 150.908 119.487 1.00 101.65 ?  354 PHE C CD1 1 
ATOM   1707 C CD2 . PHE A 1 351 ? 130.076 151.044 121.570 1.00 101.65 ?  354 PHE C CD2 1 
ATOM   1708 C CE1 . PHE A 1 351 ? 128.098 151.943 119.873 1.00 101.65 ?  354 PHE C CE1 1 
ATOM   1709 C CE2 . PHE A 1 351 ? 129.250 152.079 121.962 1.00 101.65 ?  354 PHE C CE2 1 
ATOM   1710 C CZ  . PHE A 1 351 ? 128.260 152.529 121.112 1.00 101.65 ?  354 PHE C CZ  1 
ATOM   1711 N N   . LEU B 2 1   ? 133.829 175.732 173.954 1.00 135.68 ?  4   LEU B N   1 
ATOM   1712 C CA  . LEU B 2 1   ? 134.379 176.425 175.114 1.00 135.68 ?  4   LEU B CA  1 
ATOM   1713 C C   . LEU B 2 1   ? 135.797 176.914 174.833 1.00 135.68 ?  4   LEU B C   1 
ATOM   1714 O O   . LEU B 2 1   ? 136.416 176.514 173.849 1.00 135.68 ?  4   LEU B O   1 
ATOM   1715 C CB  . LEU B 2 1   ? 134.365 175.512 176.342 1.00 135.68 ?  4   LEU B CB  1 
ATOM   1716 C CG  . LEU B 2 1   ? 134.296 176.202 177.706 1.00 135.68 ?  4   LEU B CG  1 
ATOM   1717 C CD1 . LEU B 2 1   ? 133.188 177.244 177.729 1.00 135.68 ?  4   LEU B CD1 1 
ATOM   1718 C CD2 . LEU B 2 1   ? 134.100 175.183 178.818 1.00 135.68 ?  4   LEU B CD2 1 
ATOM   1719 N N   . ASP B 2 2   ? 136.301 177.791 175.704 1.00 138.31 ?  5   ASP B N   1 
ATOM   1720 C CA  . ASP B 2 2   ? 137.645 178.327 175.519 1.00 138.31 ?  5   ASP B CA  1 
ATOM   1721 C C   . ASP B 2 2   ? 138.707 177.240 175.657 1.00 138.31 ?  5   ASP B C   1 
ATOM   1722 O O   . ASP B 2 2   ? 139.680 177.219 174.894 1.00 138.31 ?  5   ASP B O   1 
ATOM   1723 C CB  . ASP B 2 2   ? 137.897 179.461 176.512 1.00 138.31 ?  5   ASP B CB  1 
ATOM   1724 C CG  . ASP B 2 2   ? 137.883 178.990 177.954 1.00 138.31 ?  5   ASP B CG  1 
ATOM   1725 O OD1 . ASP B 2 2   ? 136.946 178.255 178.332 1.00 138.31 ?  5   ASP B OD1 1 
ATOM   1726 O OD2 . ASP B 2 2   ? 138.812 179.349 178.707 1.00 138.31 -1 5   ASP B OD2 1 
ATOM   1727 N N   . GLN B 2 3   ? 138.528 176.320 176.611 1.00 134.48 ?  6   GLN B N   1 
ATOM   1728 C CA  . GLN B 2 3   ? 139.561 175.325 176.891 1.00 134.48 ?  6   GLN B CA  1 
ATOM   1729 C C   . GLN B 2 3   ? 139.824 174.434 175.682 1.00 134.48 ?  6   GLN B C   1 
ATOM   1730 O O   . GLN B 2 3   ? 140.981 174.123 175.372 1.00 134.48 ?  6   GLN B O   1 
ATOM   1731 C CB  . GLN B 2 3   ? 139.169 174.497 178.118 1.00 134.48 ?  6   GLN B CB  1 
ATOM   1732 C CG  . GLN B 2 3   ? 137.805 173.817 178.040 1.00 134.48 ?  6   GLN B CG  1 
ATOM   1733 C CD  . GLN B 2 3   ? 137.867 172.443 177.405 1.00 134.48 ?  6   GLN B CD  1 
ATOM   1734 O OE1 . GLN B 2 3   ? 138.880 171.752 177.498 1.00 134.48 ?  6   GLN B OE1 1 
ATOM   1735 N NE2 . GLN B 2 3   ? 136.781 172.041 176.755 1.00 134.48 ?  6   GLN B NE2 1 
ATOM   1736 N N   . LEU B 2 4   ? 138.765 174.045 174.964 1.00 134.27 ?  7   LEU B N   1 
ATOM   1737 C CA  . LEU B 2 4   ? 138.934 173.217 173.774 1.00 134.27 ?  7   LEU B CA  1 
ATOM   1738 C C   . LEU B 2 4   ? 139.850 173.885 172.757 1.00 134.27 ?  7   LEU B C   1 
ATOM   1739 O O   . LEU B 2 4   ? 140.477 173.200 171.941 1.00 134.27 ?  7   LEU B O   1 
ATOM   1740 C CB  . LEU B 2 4   ? 137.569 172.912 173.153 1.00 134.27 ?  7   LEU B CB  1 
ATOM   1741 C CG  . LEU B 2 4   ? 137.530 172.146 171.829 1.00 134.27 ?  7   LEU B CG  1 
ATOM   1742 C CD1 . LEU B 2 4   ? 137.954 170.700 172.032 1.00 134.27 ?  7   LEU B CD1 1 
ATOM   1743 C CD2 . LEU B 2 4   ? 136.144 172.222 171.206 1.00 134.27 ?  7   LEU B CD2 1 
ATOM   1744 N N   . ARG B 2 5   ? 139.946 175.216 172.797 1.00 135.21 ?  8   ARG B N   1 
ATOM   1745 C CA  . ARG B 2 5   ? 140.845 175.916 171.888 1.00 135.21 ?  8   ARG B CA  1 
ATOM   1746 C C   . ARG B 2 5   ? 142.297 175.509 172.116 1.00 135.21 ?  8   ARG B C   1 
ATOM   1747 O O   . ARG B 2 5   ? 143.041 175.286 171.153 1.00 135.21 ?  8   ARG B O   1 
ATOM   1748 C CB  . ARG B 2 5   ? 140.680 177.427 172.049 1.00 135.21 ?  8   ARG B CB  1 
ATOM   1749 N N   . GLN B 2 6   ? 142.724 175.408 173.376 1.00 132.96 ?  9   GLN B N   1 
ATOM   1750 C CA  . GLN B 2 6   ? 144.127 175.123 173.661 1.00 132.96 ?  9   GLN B CA  1 
ATOM   1751 C C   . GLN B 2 6   ? 144.333 173.873 174.502 1.00 132.96 ?  9   GLN B C   1 
ATOM   1752 O O   . GLN B 2 6   ? 145.229 173.077 174.192 1.00 132.96 ?  9   GLN B O   1 
ATOM   1753 C CB  . GLN B 2 6   ? 144.802 176.339 174.331 1.00 132.96 ?  9   GLN B CB  1 
ATOM   1754 C CG  . GLN B 2 6   ? 144.356 176.656 175.754 1.00 132.96 ?  9   GLN B CG  1 
ATOM   1755 C CD  . GLN B 2 6   ? 143.104 177.503 175.795 1.00 132.96 ?  9   GLN B CD  1 
ATOM   1756 O OE1 . GLN B 2 6   ? 142.388 177.614 174.803 1.00 132.96 ?  9   GLN B OE1 1 
ATOM   1757 N NE2 . GLN B 2 6   ? 142.833 178.108 176.946 1.00 132.96 ?  9   GLN B NE2 1 
ATOM   1758 N N   . GLU B 2 7   ? 143.529 173.672 175.553 1.00 129.30 ?  10  GLU B N   1 
ATOM   1759 C CA  . GLU B 2 7   ? 143.776 172.598 176.513 1.00 129.30 ?  10  GLU B CA  1 
ATOM   1760 C C   . GLU B 2 7   ? 143.977 171.262 175.810 1.00 129.30 ?  10  GLU B C   1 
ATOM   1761 O O   . GLU B 2 7   ? 145.060 170.668 175.875 1.00 129.30 ?  10  GLU B O   1 
ATOM   1762 C CB  . GLU B 2 7   ? 142.621 172.516 177.515 1.00 129.30 ?  10  GLU B CB  1 
ATOM   1763 C CG  . GLU B 2 7   ? 142.554 171.212 178.300 1.00 129.30 ?  10  GLU B CG  1 
ATOM   1764 C CD  . GLU B 2 7   ? 143.678 171.072 179.308 1.00 129.30 ?  10  GLU B CD  1 
ATOM   1765 O OE1 . GLU B 2 7   ? 144.131 172.105 179.846 1.00 129.30 ?  10  GLU B OE1 1 
ATOM   1766 O OE2 . GLU B 2 7   ? 144.108 169.928 179.565 1.00 129.30 -1 10  GLU B OE2 1 
ATOM   1767 N N   . ALA B 2 8   ? 142.949 170.795 175.097 1.00 126.42 ?  11  ALA B N   1 
ATOM   1768 C CA  . ALA B 2 8   ? 143.079 169.564 174.327 1.00 126.42 ?  11  ALA B CA  1 
ATOM   1769 C C   . ALA B 2 8   ? 144.281 169.639 173.397 1.00 126.42 ?  11  ALA B C   1 
ATOM   1770 O O   . ALA B 2 8   ? 145.133 168.741 173.387 1.00 126.42 ?  11  ALA B O   1 
ATOM   1771 C CB  . ALA B 2 8   ? 141.797 169.300 173.537 1.00 126.42 ?  11  ALA B CB  1 
ATOM   1772 N N   . GLU B 2 9   ? 144.389 170.738 172.645 1.00 127.41 ?  12  GLU B N   1 
ATOM   1773 C CA  . GLU B 2 9   ? 145.541 170.931 171.771 1.00 127.41 ?  12  GLU B CA  1 
ATOM   1774 C C   . GLU B 2 9   ? 146.837 170.830 172.561 1.00 127.41 ?  12  GLU B C   1 
ATOM   1775 O O   . GLU B 2 9   ? 147.770 170.124 172.158 1.00 127.41 ?  12  GLU B O   1 
ATOM   1776 C CB  . GLU B 2 9   ? 145.441 172.284 171.066 1.00 127.41 ?  12  GLU B CB  1 
ATOM   1777 C CG  . GLU B 2 9   ? 144.283 172.391 170.087 1.00 127.41 ?  12  GLU B CG  1 
ATOM   1778 C CD  . GLU B 2 9   ? 144.453 171.491 168.879 1.00 127.41 ?  12  GLU B CD  1 
ATOM   1779 O OE1 . GLU B 2 9   ? 145.608 171.276 168.454 1.00 127.41 ?  12  GLU B OE1 1 
ATOM   1780 O OE2 . GLU B 2 9   ? 143.432 170.997 168.355 1.00 127.41 -1 12  GLU B OE2 1 
ATOM   1781 N N   . GLN B 2 10  ? 146.894 171.500 173.717 1.00 124.35 ?  13  GLN B N   1 
ATOM   1782 C CA  . GLN B 2 10  ? 148.076 171.414 174.566 1.00 124.35 ?  13  GLN B CA  1 
ATOM   1783 C C   . GLN B 2 10  ? 148.383 169.963 174.898 1.00 124.35 ?  13  GLN B C   1 
ATOM   1784 O O   . GLN B 2 10  ? 149.525 169.507 174.759 1.00 124.35 ?  13  GLN B O   1 
ATOM   1785 C CB  . GLN B 2 10  ? 147.865 172.238 175.839 1.00 124.35 ?  13  GLN B CB  1 
ATOM   1786 C CG  . GLN B 2 10  ? 149.100 172.384 176.718 1.00 124.35 ?  13  GLN B CG  1 
ATOM   1787 C CD  . GLN B 2 10  ? 149.280 171.227 177.681 1.00 124.35 ?  13  GLN B CD  1 
ATOM   1788 O OE1 . GLN B 2 10  ? 148.309 170.603 178.108 1.00 124.35 ?  13  GLN B OE1 1 
ATOM   1789 N NE2 . GLN B 2 10  ? 150.529 170.931 178.024 1.00 124.35 ?  13  GLN B NE2 1 
ATOM   1790 N N   . LEU B 2 11  ? 147.352 169.206 175.285 1.00 119.78 ?  14  LEU B N   1 
ATOM   1791 C CA  . LEU B 2 11  ? 147.543 167.790 175.570 1.00 119.78 ?  14  LEU B CA  1 
ATOM   1792 C C   . LEU B 2 11  ? 148.140 167.081 174.365 1.00 119.78 ?  14  LEU B C   1 
ATOM   1793 O O   . LEU B 2 11  ? 149.109 166.322 174.494 1.00 119.78 ?  14  LEU B O   1 
ATOM   1794 C CB  . LEU B 2 11  ? 146.212 167.155 175.970 1.00 119.78 ?  14  LEU B CB  1 
ATOM   1795 C CG  . LEU B 2 11  ? 145.842 167.258 177.449 1.00 119.78 ?  14  LEU B CG  1 
ATOM   1796 C CD1 . LEU B 2 11  ? 144.620 166.413 177.738 1.00 119.78 ?  14  LEU B CD1 1 
ATOM   1797 C CD2 . LEU B 2 11  ? 147.009 166.837 178.326 1.00 119.78 ?  14  LEU B CD2 1 
ATOM   1798 N N   . LYS B 2 12  ? 147.601 167.361 173.174 1.00 119.27 ?  15  LYS B N   1 
ATOM   1799 C CA  . LYS B 2 12  ? 148.158 166.791 171.953 1.00 119.27 ?  15  LYS B CA  1 
ATOM   1800 C C   . LYS B 2 12  ? 149.651 167.065 171.874 1.00 119.27 ?  15  LYS B C   1 
ATOM   1801 O O   . LYS B 2 12  ? 150.454 166.147 171.662 1.00 119.27 ?  15  LYS B O   1 
ATOM   1802 C CB  . LYS B 2 12  ? 147.439 167.363 170.731 1.00 119.27 ?  15  LYS B CB  1 
ATOM   1803 C CG  . LYS B 2 12  ? 146.196 166.596 170.318 1.00 119.27 ?  15  LYS B CG  1 
ATOM   1804 C CD  . LYS B 2 12  ? 145.514 167.260 169.132 1.00 119.27 ?  15  LYS B CD  1 
ATOM   1805 C CE  . LYS B 2 12  ? 144.143 166.660 168.874 1.00 119.27 ?  15  LYS B CE  1 
ATOM   1806 N NZ  . LYS B 2 12  ? 144.222 165.204 168.572 1.00 119.27 1  15  LYS B NZ  1 
ATOM   1807 N N   . ASN B 2 13  ? 150.042 168.323 172.100 1.00 117.58 ?  16  ASN B N   1 
ATOM   1808 C CA  . ASN B 2 13  ? 151.457 168.673 172.087 1.00 117.58 ?  16  ASN B CA  1 
ATOM   1809 C C   . ASN B 2 13  ? 152.236 167.772 173.034 1.00 117.58 ?  16  ASN B C   1 
ATOM   1810 O O   . ASN B 2 13  ? 153.229 167.147 172.639 1.00 117.58 ?  16  ASN B O   1 
ATOM   1811 C CB  . ASN B 2 13  ? 151.637 170.142 172.470 1.00 117.58 ?  16  ASN B CB  1 
ATOM   1812 C CG  . ASN B 2 13  ? 151.031 171.088 171.453 1.00 117.58 ?  16  ASN B CG  1 
ATOM   1813 O OD1 . ASN B 2 13  ? 151.022 170.807 170.255 1.00 117.58 ?  16  ASN B OD1 1 
ATOM   1814 N ND2 . ASN B 2 13  ? 150.522 172.219 171.927 1.00 117.58 ?  16  ASN B ND2 1 
ATOM   1815 N N   . GLN B 2 14  ? 151.750 167.641 174.272 1.00 114.24 ?  17  GLN B N   1 
ATOM   1816 C CA  . GLN B 2 14  ? 152.421 166.792 175.248 1.00 114.24 ?  17  GLN B CA  1 
ATOM   1817 C C   . GLN B 2 14  ? 152.605 165.389 174.694 1.00 114.24 ?  17  GLN B C   1 
ATOM   1818 O O   . GLN B 2 14  ? 153.703 164.822 174.756 1.00 114.24 ?  17  GLN B O   1 
ATOM   1819 C CB  . GLN B 2 14  ? 151.625 166.760 176.553 1.00 114.24 ?  17  GLN B CB  1 
ATOM   1820 C CG  . GLN B 2 14  ? 151.979 165.598 177.466 1.00 114.24 ?  17  GLN B CG  1 
ATOM   1821 C CD  . GLN B 2 14  ? 151.159 165.588 178.741 1.00 114.24 ?  17  GLN B CD  1 
ATOM   1822 O OE1 . GLN B 2 14  ? 150.471 166.558 179.057 1.00 114.24 ?  17  GLN B OE1 1 
ATOM   1823 N NE2 . GLN B 2 14  ? 151.227 164.487 179.480 1.00 114.24 ?  17  GLN B NE2 1 
ATOM   1824 N N   . ILE B 2 15  ? 151.547 164.840 174.088 1.00 109.87 ?  18  ILE B N   1 
ATOM   1825 C CA  . ILE B 2 15  ? 151.630 163.492 173.536 1.00 109.87 ?  18  ILE B CA  1 
ATOM   1826 C C   . ILE B 2 15  ? 152.787 163.404 172.553 1.00 109.87 ?  18  ILE B C   1 
ATOM   1827 O O   . ILE B 2 15  ? 153.644 162.517 172.656 1.00 109.87 ?  18  ILE B O   1 
ATOM   1828 C CB  . ILE B 2 15  ? 150.296 163.094 172.879 1.00 109.87 ?  18  ILE B CB  1 
ATOM   1829 C CG1 . ILE B 2 15  ? 149.181 163.053 173.924 1.00 109.87 ?  18  ILE B CG1 1 
ATOM   1830 C CG2 . ILE B 2 15  ? 150.426 161.751 172.182 1.00 109.87 ?  18  ILE B CG2 1 
ATOM   1831 C CD1 . ILE B 2 15  ? 147.798 162.924 173.332 1.00 109.87 ?  18  ILE B CD1 1 
ATOM   1832 N N   . ARG B 2 16  ? 152.870 164.369 171.631 1.00 111.31 ?  19  ARG B N   1 
ATOM   1833 C CA  . ARG B 2 16  ? 153.957 164.348 170.660 1.00 111.31 ?  19  ARG B CA  1 
ATOM   1834 C C   . ARG B 2 16  ? 155.300 164.367 171.372 1.00 111.31 ?  19  ARG B C   1 
ATOM   1835 O O   . ARG B 2 16  ? 156.192 163.566 171.064 1.00 111.31 ?  19  ARG B O   1 
ATOM   1836 C CB  . ARG B 2 16  ? 153.840 165.529 169.696 1.00 111.31 ?  19  ARG B CB  1 
ATOM   1837 C CG  . ARG B 2 16  ? 152.648 165.456 168.759 1.00 111.31 ?  19  ARG B CG  1 
ATOM   1838 C CD  . ARG B 2 16  ? 152.649 166.623 167.784 1.00 111.31 ?  19  ARG B CD  1 
ATOM   1839 N NE  . ARG B 2 16  ? 152.382 167.897 168.440 1.00 111.31 ?  19  ARG B NE  1 
ATOM   1840 C CZ  . ARG B 2 16  ? 153.268 168.876 168.554 1.00 111.31 ?  19  ARG B CZ  1 
ATOM   1841 N NH1 . ARG B 2 16  ? 154.494 168.759 168.072 1.00 111.31 1  19  ARG B NH1 1 
ATOM   1842 N NH2 . ARG B 2 16  ? 152.916 170.002 169.168 1.00 111.31 ?  19  ARG B NH2 1 
ATOM   1843 N N   . ASP B 2 17  ? 155.433 165.235 172.380 1.00 108.45 ?  20  ASP B N   1 
ATOM   1844 C CA  . ASP B 2 17  ? 156.680 165.291 173.130 1.00 108.45 ?  20  ASP B CA  1 
ATOM   1845 C C   . ASP B 2 17  ? 156.995 163.937 173.743 1.00 108.45 ?  20  ASP B C   1 
ATOM   1846 O O   . ASP B 2 17  ? 158.131 163.455 173.648 1.00 108.45 ?  20  ASP B O   1 
ATOM   1847 C CB  . ASP B 2 17  ? 156.598 166.370 174.209 1.00 108.45 ?  20  ASP B CB  1 
ATOM   1848 C CG  . ASP B 2 17  ? 156.497 167.766 173.627 1.00 108.45 ?  20  ASP B CG  1 
ATOM   1849 O OD1 . ASP B 2 17  ? 156.883 167.951 172.454 1.00 108.45 ?  20  ASP B OD1 1 
ATOM   1850 O OD2 . ASP B 2 17  ? 156.033 168.678 174.343 1.00 108.45 -1 20  ASP B OD2 1 
ATOM   1851 N N   . ALA B 2 18  ? 155.984 163.281 174.322 1.00 103.82 ?  21  ALA B N   1 
ATOM   1852 C CA  . ALA B 2 18  ? 156.202 161.950 174.871 1.00 103.82 ?  21  ALA B CA  1 
ATOM   1853 C C   . ALA B 2 18  ? 156.730 161.012 173.799 1.00 103.82 ?  21  ALA B C   1 
ATOM   1854 O O   . ALA B 2 18  ? 157.721 160.302 174.016 1.00 103.82 ?  21  ALA B O   1 
ATOM   1855 C CB  . ALA B 2 18  ? 154.909 161.408 175.478 1.00 103.82 ?  21  ALA B CB  1 
ATOM   1856 N N   . ARG B 2 19  ? 156.116 161.037 172.614 1.00 96.17  ?  22  ARG B N   1 
ATOM   1857 C CA  . ARG B 2 19  ? 156.630 160.228 171.518 1.00 96.17  ?  22  ARG B CA  1 
ATOM   1858 C C   . ARG B 2 19  ? 158.039 160.664 171.149 1.00 96.17  ?  22  ARG B C   1 
ATOM   1859 O O   . ARG B 2 19  ? 158.931 159.825 170.967 1.00 96.17  ?  22  ARG B O   1 
ATOM   1860 C CB  . ARG B 2 19  ? 155.690 160.317 170.317 1.00 96.17  ?  22  ARG B CB  1 
ATOM   1861 C CG  . ARG B 2 19  ? 154.396 159.540 170.508 1.00 96.17  ?  22  ARG B CG  1 
ATOM   1862 C CD  . ARG B 2 19  ? 153.327 159.960 169.517 1.00 96.17  ?  22  ARG B CD  1 
ATOM   1863 N NE  . ARG B 2 19  ? 151.990 159.652 170.009 1.00 96.17  ?  22  ARG B NE  1 
ATOM   1864 C CZ  . ARG B 2 19  ? 150.996 159.206 169.254 1.00 96.17  ?  22  ARG B CZ  1 
ATOM   1865 N NH1 . ARG B 2 19  ? 151.152 159.001 167.956 1.00 96.17  1  22  ARG B NH1 1 
ATOM   1866 N NH2 . ARG B 2 19  ? 149.816 158.958 169.815 1.00 96.17  ?  22  ARG B NH2 1 
ATOM   1867 N N   . LYS B 2 20  ? 158.273 161.977 171.090 1.00 100.61 ?  23  LYS B N   1 
ATOM   1868 C CA  . LYS B 2 20  ? 159.613 162.473 170.812 1.00 100.61 ?  23  LYS B CA  1 
ATOM   1869 C C   . LYS B 2 20  ? 160.594 162.063 171.900 1.00 100.61 ?  23  LYS B C   1 
ATOM   1870 O O   . LYS B 2 20  ? 161.799 161.979 171.638 1.00 100.61 ?  23  LYS B O   1 
ATOM   1871 C CB  . LYS B 2 20  ? 159.581 163.996 170.655 1.00 100.61 ?  23  LYS B CB  1 
ATOM   1872 C CG  . LYS B 2 20  ? 160.917 164.630 170.306 1.00 100.61 ?  23  LYS B CG  1 
ATOM   1873 C CD  . LYS B 2 20  ? 161.423 164.131 168.963 1.00 100.61 ?  23  LYS B CD  1 
ATOM   1874 C CE  . LYS B 2 20  ? 160.514 164.579 167.830 1.00 100.61 ?  23  LYS B CE  1 
ATOM   1875 N NZ  . LYS B 2 20  ? 160.569 166.052 167.622 1.00 100.61 1  23  LYS B NZ  1 
ATOM   1876 N N   . ALA B 2 21  ? 160.102 161.782 173.107 1.00 99.95  ?  24  ALA B N   1 
ATOM   1877 C CA  . ALA B 2 21  ? 160.969 161.343 174.189 1.00 99.95  ?  24  ALA B CA  1 
ATOM   1878 C C   . ALA B 2 21  ? 161.377 159.882 174.067 1.00 99.95  ?  24  ALA B C   1 
ATOM   1879 O O   . ALA B 2 21  ? 162.278 159.449 174.794 1.00 99.95  ?  24  ALA B O   1 
ATOM   1880 C CB  . ALA B 2 21  ? 160.285 161.572 175.538 1.00 99.95  ?  24  ALA B CB  1 
ATOM   1881 N N   . CYS B 2 22  ? 160.748 159.113 173.176 1.00 96.06  ?  25  CYS B N   1 
ATOM   1882 C CA  . CYS B 2 22  ? 161.048 157.694 173.059 1.00 96.06  ?  25  CYS B CA  1 
ATOM   1883 C C   . CYS B 2 22  ? 161.677 157.305 171.729 1.00 96.06  ?  25  CYS B C   1 
ATOM   1884 O O   . CYS B 2 22  ? 162.166 156.177 171.605 1.00 96.06  ?  25  CYS B O   1 
ATOM   1885 C CB  . CYS B 2 22  ? 159.776 156.861 173.281 1.00 96.06  ?  25  CYS B CB  1 
ATOM   1886 S SG  . CYS B 2 22  ? 159.192 156.837 174.990 1.00 96.06  ?  25  CYS B SG  1 
ATOM   1887 N N   . ALA B 2 23  ? 161.686 158.197 170.741 1.00 94.46  ?  26  ALA B N   1 
ATOM   1888 C CA  . ALA B 2 23  ? 162.241 157.886 169.424 1.00 94.46  ?  26  ALA B CA  1 
ATOM   1889 C C   . ALA B 2 23  ? 163.743 158.177 169.386 1.00 94.46  ?  26  ALA B C   1 
ATOM   1890 O O   . ALA B 2 23  ? 164.236 158.981 168.595 1.00 94.46  ?  26  ALA B O   1 
ATOM   1891 C CB  . ALA B 2 23  ? 161.499 158.662 168.343 1.00 94.46  ?  26  ALA B CB  1 
ATOM   1892 N N   . ASP B 2 24  ? 164.475 157.501 170.275 1.00 97.23  ?  27  ASP B N   1 
ATOM   1893 C CA  . ASP B 2 24  ? 165.928 157.638 170.288 1.00 97.23  ?  27  ASP B CA  1 
ATOM   1894 C C   . ASP B 2 24  ? 166.546 157.086 169.009 1.00 97.23  ?  27  ASP B C   1 
ATOM   1895 O O   . ASP B 2 24  ? 167.455 157.698 168.436 1.00 97.23  ?  27  ASP B O   1 
ATOM   1896 C CB  . ASP B 2 24  ? 166.514 156.940 171.515 1.00 97.23  ?  27  ASP B CB  1 
ATOM   1897 C CG  . ASP B 2 24  ? 165.924 155.561 171.741 1.00 97.23  ?  27  ASP B CG  1 
ATOM   1898 O OD1 . ASP B 2 24  ? 165.788 154.797 170.763 1.00 97.23  ?  27  ASP B OD1 1 
ATOM   1899 O OD2 . ASP B 2 24  ? 165.600 155.238 172.903 1.00 97.23  -1 27  ASP B OD2 1 
ATOM   1900 N N   . ALA B 2 25  ? 166.067 155.933 168.550 1.00 93.08  ?  28  ALA B N   1 
ATOM   1901 C CA  . ALA B 2 25  ? 166.535 155.303 167.325 1.00 93.08  ?  28  ALA B CA  1 
ATOM   1902 C C   . ALA B 2 25  ? 165.328 154.898 166.488 1.00 93.08  ?  28  ALA B C   1 
ATOM   1903 O O   . ALA B 2 25  ? 164.178 155.005 166.923 1.00 93.08  ?  28  ALA B O   1 
ATOM   1904 C CB  . ALA B 2 25  ? 167.428 154.094 167.628 1.00 93.08  ?  28  ALA B CB  1 
ATOM   1905 N N   . THR B 2 26  ? 165.594 154.431 165.273 1.00 89.52  ?  29  THR B N   1 
ATOM   1906 C CA  . THR B 2 26  ? 164.554 153.997 164.355 1.00 89.52  ?  29  THR B CA  1 
ATOM   1907 C C   . THR B 2 26  ? 164.681 152.500 164.103 1.00 89.52  ?  29  THR B C   1 
ATOM   1908 O O   . THR B 2 26  ? 165.695 151.873 164.419 1.00 89.52  ?  29  THR B O   1 
ATOM   1909 C CB  . THR B 2 26  ? 164.625 154.766 163.030 1.00 89.52  ?  29  THR B CB  1 
ATOM   1910 O OG1 . THR B 2 26  ? 165.926 154.605 162.451 1.00 89.52  ?  29  THR B OG1 1 
ATOM   1911 C CG2 . THR B 2 26  ? 164.359 156.244 163.259 1.00 89.52  ?  29  THR B CG2 1 
ATOM   1912 N N   . LEU B 2 27  ? 163.622 151.928 163.525 1.00 83.37  ?  30  LEU B N   1 
ATOM   1913 C CA  . LEU B 2 27  ? 163.631 150.502 163.215 1.00 83.37  ?  30  LEU B CA  1 
ATOM   1914 C C   . LEU B 2 27  ? 164.673 150.165 162.157 1.00 83.37  ?  30  LEU B C   1 
ATOM   1915 O O   . LEU B 2 27  ? 165.279 149.090 162.209 1.00 83.37  ?  30  LEU B O   1 
ATOM   1916 C CB  . LEU B 2 27  ? 162.241 150.055 162.762 1.00 83.37  ?  30  LEU B CB  1 
ATOM   1917 C CG  . LEU B 2 27  ? 162.004 148.554 162.575 1.00 83.37  ?  30  LEU B CG  1 
ATOM   1918 C CD1 . LEU B 2 27  ? 162.622 147.744 163.696 1.00 83.37  ?  30  LEU B CD1 1 
ATOM   1919 C CD2 . LEU B 2 27  ? 160.516 148.262 162.465 1.00 83.37  ?  30  LEU B CD2 1 
ATOM   1920 N N   . SER B 2 28  ? 164.888 151.059 161.190 1.00 87.58  ?  31  SER B N   1 
ATOM   1921 C CA  . SER B 2 28  ? 165.895 150.808 160.163 1.00 87.58  ?  31  SER B CA  1 
ATOM   1922 C C   . SER B 2 28  ? 167.295 150.745 160.760 1.00 87.58  ?  31  SER B C   1 
ATOM   1923 O O   . SER B 2 28  ? 168.094 149.872 160.397 1.00 87.58  ?  31  SER B O   1 
ATOM   1924 C CB  . SER B 2 28  ? 165.819 151.886 159.082 1.00 87.58  ?  31  SER B CB  1 
ATOM   1925 O OG  . SER B 2 28  ? 164.511 151.978 158.546 1.00 87.58  ?  31  SER B OG  1 
ATOM   1926 N N   . GLN B 2 29  ? 167.612 151.661 161.679 1.00 89.63  ?  32  GLN B N   1 
ATOM   1927 C CA  . GLN B 2 29  ? 168.929 151.650 162.305 1.00 89.63  ?  32  GLN B CA  1 
ATOM   1928 C C   . GLN B 2 29  ? 169.154 150.368 163.095 1.00 89.63  ?  32  GLN B C   1 
ATOM   1929 O O   . GLN B 2 29  ? 170.246 149.790 163.057 1.00 89.63  ?  32  GLN B O   1 
ATOM   1930 C CB  . GLN B 2 29  ? 169.093 152.872 163.209 1.00 89.63  ?  32  GLN B CB  1 
ATOM   1931 C CG  . GLN B 2 29  ? 169.174 154.192 162.463 1.00 89.63  ?  32  GLN B CG  1 
ATOM   1932 C CD  . GLN B 2 29  ? 169.159 155.387 163.395 1.00 89.63  ?  32  GLN B CD  1 
ATOM   1933 O OE1 . GLN B 2 29  ? 168.229 156.194 163.375 1.00 89.63  ?  32  GLN B OE1 1 
ATOM   1934 N NE2 . GLN B 2 29  ? 170.192 155.506 164.221 1.00 89.63  ?  32  GLN B NE2 1 
ATOM   1935 N N   . ILE B 2 30  ? 168.134 149.912 163.825 1.00 86.52  ?  33  ILE B N   1 
ATOM   1936 C CA  . ILE B 2 30  ? 168.264 148.675 164.587 1.00 86.52  ?  33  ILE B CA  1 
ATOM   1937 C C   . ILE B 2 30  ? 168.432 147.485 163.650 1.00 86.52  ?  33  ILE B C   1 
ATOM   1938 O O   . ILE B 2 30  ? 169.363 146.685 163.798 1.00 86.52  ?  33  ILE B O   1 
ATOM   1939 C CB  . ILE B 2 30  ? 167.055 148.491 165.520 1.00 86.52  ?  33  ILE B CB  1 
ATOM   1940 C CG1 . ILE B 2 30  ? 166.980 149.640 166.528 1.00 86.52  ?  33  ILE B CG1 1 
ATOM   1941 C CG2 . ILE B 2 30  ? 167.133 147.153 166.236 1.00 86.52  ?  33  ILE B CG2 1 
ATOM   1942 C CD1 . ILE B 2 30  ? 168.143 149.682 167.491 1.00 86.52  ?  33  ILE B CD1 1 
ATOM   1943 N N   . THR B 2 31  ? 167.539 147.350 162.674 1.00 84.76  ?  34  THR B N   1 
ATOM   1944 C CA  . THR B 2 31  ? 167.626 146.262 161.699 1.00 84.76  ?  34  THR B CA  1 
ATOM   1945 C C   . THR B 2 31  ? 168.347 146.699 160.427 1.00 84.76  ?  34  THR B C   1 
ATOM   1946 O O   . THR B 2 31  ? 167.871 146.484 159.314 1.00 84.76  ?  34  THR B O   1 
ATOM   1947 C CB  . THR B 2 31  ? 166.231 145.740 161.379 1.00 84.76  ?  34  THR B CB  1 
ATOM   1948 O OG1 . THR B 2 31  ? 165.522 146.713 160.603 1.00 84.76  ?  34  THR B OG1 1 
ATOM   1949 C CG2 . THR B 2 31  ? 165.460 145.464 162.660 1.00 84.76  ?  34  THR B CG2 1 
ATOM   1950 N N   . ASN B 2 32  ? 169.511 147.324 160.589 1.00 90.84  ?  35  ASN B N   1 
ATOM   1951 C CA  . ASN B 2 32  ? 170.380 147.615 159.456 1.00 90.84  ?  35  ASN B CA  1 
ATOM   1952 C C   . ASN B 2 32  ? 171.374 146.497 159.178 1.00 90.84  ?  35  ASN B C   1 
ATOM   1953 O O   . ASN B 2 32  ? 171.755 146.292 158.020 1.00 90.84  ?  35  ASN B O   1 
ATOM   1954 C CB  . ASN B 2 32  ? 171.137 148.924 159.692 1.00 90.84  ?  35  ASN B CB  1 
ATOM   1955 C CG  . ASN B 2 32  ? 171.398 149.685 158.408 1.00 90.84  ?  35  ASN B CG  1 
ATOM   1956 O OD1 . ASN B 2 32  ? 171.231 149.151 157.312 1.00 90.84  ?  35  ASN B OD1 1 
ATOM   1957 N ND2 . ASN B 2 32  ? 171.811 150.940 158.538 1.00 90.84  ?  35  ASN B ND2 1 
ATOM   1958 N N   . ASN B 2 33  ? 171.801 145.773 160.209 1.00 93.02  ?  36  ASN B N   1 
ATOM   1959 C CA  . ASN B 2 33  ? 172.757 144.685 160.059 1.00 93.02  ?  36  ASN B CA  1 
ATOM   1960 C C   . ASN B 2 33  ? 172.092 143.337 159.814 1.00 93.02  ?  36  ASN B C   1 
ATOM   1961 O O   . ASN B 2 33  ? 172.796 142.349 159.582 1.00 93.02  ?  36  ASN B O   1 
ATOM   1962 C CB  . ASN B 2 33  ? 173.651 144.597 161.299 1.00 93.02  ?  36  ASN B CB  1 
ATOM   1963 C CG  . ASN B 2 33  ? 174.331 145.913 161.620 1.00 93.02  ?  36  ASN B CG  1 
ATOM   1964 O OD1 . ASN B 2 33  ? 174.120 146.916 160.939 1.00 93.02  ?  36  ASN B OD1 1 
ATOM   1965 N ND2 . ASN B 2 33  ? 175.153 145.916 162.663 1.00 93.02  ?  36  ASN B ND2 1 
ATOM   1966 N N   . ILE B 2 34  ? 170.761 143.270 159.862 1.00 87.77  ?  37  ILE B N   1 
ATOM   1967 C CA  . ILE B 2 34  ? 170.062 142.018 159.609 1.00 87.77  ?  37  ILE B CA  1 
ATOM   1968 C C   . ILE B 2 34  ? 170.192 141.645 158.140 1.00 87.77  ?  37  ILE B C   1 
ATOM   1969 O O   . ILE B 2 34  ? 170.091 142.500 157.249 1.00 87.77  ?  37  ILE B O   1 
ATOM   1970 C CB  . ILE B 2 34  ? 168.588 142.133 160.033 1.00 87.77  ?  37  ILE B CB  1 
ATOM   1971 C CG1 . ILE B 2 34  ? 168.497 142.477 161.518 1.00 87.77  ?  37  ILE B CG1 1 
ATOM   1972 C CG2 . ILE B 2 34  ? 167.837 140.844 159.742 1.00 87.77  ?  37  ILE B CG2 1 
ATOM   1973 C CD1 . ILE B 2 34  ? 169.117 141.429 162.414 1.00 87.77  ?  37  ILE B CD1 1 
ATOM   1974 N N   . ASP B 2 35  ? 170.431 140.364 157.881 1.00 90.32  ?  38  ASP B N   1 
ATOM   1975 C CA  . ASP B 2 35  ? 170.561 139.890 156.512 1.00 90.32  ?  38  ASP B CA  1 
ATOM   1976 C C   . ASP B 2 35  ? 169.247 140.098 155.765 1.00 90.32  ?  38  ASP B C   1 
ATOM   1977 O O   . ASP B 2 35  ? 168.176 139.803 156.312 1.00 90.32  ?  38  ASP B O   1 
ATOM   1978 C CB  . ASP B 2 35  ? 170.950 138.412 156.493 1.00 90.32  ?  38  ASP B CB  1 
ATOM   1979 C CG  . ASP B 2 35  ? 172.451 138.205 156.465 1.00 90.32  ?  38  ASP B CG  1 
ATOM   1980 O OD1 . ASP B 2 35  ? 173.173 139.134 156.046 1.00 90.32  ?  38  ASP B OD1 1 
ATOM   1981 O OD2 . ASP B 2 35  ? 172.908 137.113 156.862 1.00 90.32  -1 38  ASP B OD2 1 
ATOM   1982 N N   . PRO B 2 36  ? 169.281 140.604 154.535 1.00 83.17  ?  39  PRO B N   1 
ATOM   1983 C CA  . PRO B 2 36  ? 168.035 140.831 153.798 1.00 83.17  ?  39  PRO B CA  1 
ATOM   1984 C C   . PRO B 2 36  ? 167.320 139.527 153.486 1.00 83.17  ?  39  PRO B C   1 
ATOM   1985 O O   . PRO B 2 36  ? 167.934 138.464 153.362 1.00 83.17  ?  39  PRO B O   1 
ATOM   1986 C CB  . PRO B 2 36  ? 168.501 141.530 152.516 1.00 83.17  ?  39  PRO B CB  1 
ATOM   1987 C CG  . PRO B 2 36  ? 169.932 141.143 152.370 1.00 83.17  ?  39  PRO B CG  1 
ATOM   1988 C CD  . PRO B 2 36  ? 170.467 141.011 153.763 1.00 83.17  ?  39  PRO B CD  1 
ATOM   1989 N N   . VAL B 2 37  ? 165.995 139.624 153.370 1.00 77.21  ?  40  VAL B N   1 
ATOM   1990 C CA  . VAL B 2 37  ? 165.185 138.454 153.043 1.00 77.21  ?  40  VAL B CA  1 
ATOM   1991 C C   . VAL B 2 37  ? 165.547 137.926 151.662 1.00 77.21  ?  40  VAL B C   1 
ATOM   1992 O O   . VAL B 2 37  ? 165.634 136.711 151.445 1.00 77.21  ?  40  VAL B O   1 
ATOM   1993 C CB  . VAL B 2 37  ? 163.687 138.802 153.146 1.00 77.21  ?  40  VAL B CB  1 
ATOM   1994 C CG1 . VAL B 2 37  ? 162.843 137.795 152.381 1.00 77.21  ?  40  VAL B CG1 1 
ATOM   1995 C CG2 . VAL B 2 37  ? 163.261 138.866 154.601 1.00 77.21  ?  40  VAL B CG2 1 
ATOM   1996 N N   . GLY B 2 38  ? 165.781 138.827 150.712 1.00 82.60  ?  41  GLY B N   1 
ATOM   1997 C CA  . GLY B 2 38  ? 166.058 138.434 149.347 1.00 82.60  ?  41  GLY B CA  1 
ATOM   1998 C C   . GLY B 2 38  ? 164.800 138.370 148.509 1.00 82.60  ?  41  GLY B C   1 
ATOM   1999 O O   . GLY B 2 38  ? 163.690 138.684 148.949 1.00 82.60  ?  41  GLY B O   1 
ATOM   2000 N N   . ARG B 2 39  ? 164.984 137.954 147.260 1.00 82.50  ?  42  ARG B N   1 
ATOM   2001 C CA  . ARG B 2 39  ? 163.857 137.845 146.345 1.00 82.50  ?  42  ARG B CA  1 
ATOM   2002 C C   . ARG B 2 39  ? 162.903 136.751 146.806 1.00 82.50  ?  42  ARG B C   1 
ATOM   2003 O O   . ARG B 2 39  ? 163.323 135.650 147.171 1.00 82.50  ?  42  ARG B O   1 
ATOM   2004 C CB  . ARG B 2 39  ? 164.346 137.558 144.927 1.00 82.50  ?  42  ARG B CB  1 
ATOM   2005 C CG  . ARG B 2 39  ? 163.294 137.794 143.858 1.00 82.50  ?  42  ARG B CG  1 
ATOM   2006 C CD  . ARG B 2 39  ? 162.798 139.231 143.890 1.00 82.50  ?  42  ARG B CD  1 
ATOM   2007 N NE  . ARG B 2 39  ? 161.755 139.475 142.902 1.00 82.50  ?  42  ARG B NE  1 
ATOM   2008 C CZ  . ARG B 2 39  ? 161.153 140.643 142.721 1.00 82.50  ?  42  ARG B CZ  1 
ATOM   2009 N NH1 . ARG B 2 39  ? 161.468 141.702 143.448 1.00 82.50  1  42  ARG B NH1 1 
ATOM   2010 N NH2 . ARG B 2 39  ? 160.212 140.750 141.788 1.00 82.50  ?  42  ARG B NH2 1 
ATOM   2011 N N   . ILE B 2 40  ? 161.611 137.064 146.789 1.00 78.74  ?  43  ILE B N   1 
ATOM   2012 C CA  . ILE B 2 40  ? 160.563 136.141 147.207 1.00 78.74  ?  43  ILE B CA  1 
ATOM   2013 C C   . ILE B 2 40  ? 159.705 135.831 145.990 1.00 78.74  ?  43  ILE B C   1 
ATOM   2014 O O   . ILE B 2 40  ? 159.114 136.737 145.390 1.00 78.74  ?  43  ILE B O   1 
ATOM   2015 C CB  . ILE B 2 40  ? 159.716 136.724 148.347 1.00 78.74  ?  43  ILE B CB  1 
ATOM   2016 C CG1 . ILE B 2 40  ? 160.526 136.774 149.644 1.00 78.74  ?  43  ILE B CG1 1 
ATOM   2017 C CG2 . ILE B 2 40  ? 158.449 135.912 148.533 1.00 78.74  ?  43  ILE B CG2 1 
ATOM   2018 C CD1 . ILE B 2 40  ? 160.607 135.450 150.368 1.00 78.74  ?  43  ILE B CD1 1 
ATOM   2019 N N   . GLN B 2 41  ? 159.634 134.553 145.627 1.00 81.18  ?  44  GLN B N   1 
ATOM   2020 C CA  . GLN B 2 41  ? 158.883 134.103 144.459 1.00 81.18  ?  44  GLN B CA  1 
ATOM   2021 C C   . GLN B 2 41  ? 157.810 133.125 144.917 1.00 81.18  ?  44  GLN B C   1 
ATOM   2022 O O   . GLN B 2 41  ? 158.125 132.025 145.384 1.00 81.18  ?  44  GLN B O   1 
ATOM   2023 C CB  . GLN B 2 41  ? 159.809 133.456 143.430 1.00 81.18  ?  44  GLN B CB  1 
ATOM   2024 C CG  . GLN B 2 41  ? 161.045 134.277 143.104 1.00 81.18  ?  44  GLN B CG  1 
ATOM   2025 C CD  . GLN B 2 41  ? 160.927 135.003 141.779 1.00 81.18  ?  44  GLN B CD  1 
ATOM   2026 O OE1 . GLN B 2 41  ? 159.836 135.139 141.227 1.00 81.18  ?  44  GLN B OE1 1 
ATOM   2027 N NE2 . GLN B 2 41  ? 162.055 135.475 141.262 1.00 81.18  ?  44  GLN B NE2 1 
ATOM   2028 N N   . MET B 2 42  ? 156.549 133.524 144.785 1.00 70.89  ?  45  MET B N   1 
ATOM   2029 C CA  . MET B 2 42  ? 155.415 132.657 145.063 1.00 70.89  ?  45  MET B CA  1 
ATOM   2030 C C   . MET B 2 42  ? 154.645 132.394 143.777 1.00 70.89  ?  45  MET B C   1 
ATOM   2031 O O   . MET B 2 42  ? 154.387 133.315 142.997 1.00 70.89  ?  45  MET B O   1 
ATOM   2032 C CB  . MET B 2 42  ? 154.479 133.268 146.110 1.00 70.89  ?  45  MET B CB  1 
ATOM   2033 C CG  . MET B 2 42  ? 155.136 133.610 147.437 1.00 70.89  ?  45  MET B CG  1 
ATOM   2034 S SD  . MET B 2 42  ? 153.983 134.442 148.546 1.00 70.89  ?  45  MET B SD  1 
ATOM   2035 C CE  . MET B 2 42  ? 155.106 135.252 149.678 1.00 70.89  ?  45  MET B CE  1 
ATOM   2036 N N   . ARG B 2 43  ? 154.283 131.135 143.563 1.00 67.84  ?  46  ARG B N   1 
ATOM   2037 C CA  . ARG B 2 43  ? 153.539 130.723 142.384 1.00 67.84  ?  46  ARG B CA  1 
ATOM   2038 C C   . ARG B 2 43  ? 152.081 130.469 142.745 1.00 67.84  ?  46  ARG B C   1 
ATOM   2039 O O   . ARG B 2 43  ? 151.758 130.098 143.876 1.00 67.84  ?  46  ARG B O   1 
ATOM   2040 C CB  . ARG B 2 43  ? 154.149 129.464 141.767 1.00 67.84  ?  46  ARG B CB  1 
ATOM   2041 C CG  . ARG B 2 43  ? 155.561 129.650 141.240 1.00 67.84  ?  46  ARG B CG  1 
ATOM   2042 C CD  . ARG B 2 43  ? 155.577 130.547 140.014 1.00 67.84  ?  46  ARG B CD  1 
ATOM   2043 N NE  . ARG B 2 43  ? 156.908 130.648 139.428 1.00 67.84  ?  46  ARG B NE  1 
ATOM   2044 C CZ  . ARG B 2 43  ? 157.799 131.576 139.748 1.00 67.84  ?  46  ARG B CZ  1 
ATOM   2045 N NH1 . ARG B 2 43  ? 157.533 132.509 140.648 1.00 67.84  1  46  ARG B NH1 1 
ATOM   2046 N NH2 . ARG B 2 43  ? 158.986 131.569 139.149 1.00 67.84  ?  46  ARG B NH2 1 
ATOM   2047 N N   . THR B 2 44  ? 151.202 130.675 141.770 1.00 58.36  ?  47  THR B N   1 
ATOM   2048 C CA  . THR B 2 44  ? 149.773 130.446 141.965 1.00 58.36  ?  47  THR B CA  1 
ATOM   2049 C C   . THR B 2 44  ? 149.522 128.945 142.014 1.00 58.36  ?  47  THR B C   1 
ATOM   2050 O O   . THR B 2 44  ? 149.383 128.290 140.980 1.00 58.36  ?  47  THR B O   1 
ATOM   2051 C CB  . THR B 2 44  ? 148.968 131.102 140.851 1.00 58.36  ?  47  THR B CB  1 
ATOM   2052 O OG1 . THR B 2 44  ? 149.429 132.444 140.653 1.00 58.36  ?  47  THR B OG1 1 
ATOM   2053 C CG2 . THR B 2 44  ? 147.493 131.130 141.210 1.00 58.36  ?  47  THR B CG2 1 
ATOM   2054 N N   . ARG B 2 45  ? 149.468 128.394 143.227 1.00 60.56  ?  48  ARG B N   1 
ATOM   2055 C CA  . ARG B 2 45  ? 149.250 126.961 143.380 1.00 60.56  ?  48  ARG B CA  1 
ATOM   2056 C C   . ARG B 2 45  ? 147.814 126.579 143.044 1.00 60.56  ?  48  ARG B C   1 
ATOM   2057 O O   . ARG B 2 45  ? 147.577 125.573 142.366 1.00 60.56  ?  48  ARG B O   1 
ATOM   2058 C CB  . ARG B 2 45  ? 149.602 126.531 144.802 1.00 60.56  ?  48  ARG B CB  1 
ATOM   2059 C CG  . ARG B 2 45  ? 151.056 126.758 145.175 1.00 60.56  ?  48  ARG B CG  1 
ATOM   2060 C CD  . ARG B 2 45  ? 151.987 126.282 144.074 1.00 60.56  ?  48  ARG B CD  1 
ATOM   2061 N NE  . ARG B 2 45  ? 153.308 126.891 144.173 1.00 60.56  ?  48  ARG B NE  1 
ATOM   2062 C CZ  . ARG B 2 45  ? 154.352 126.323 144.760 1.00 60.56  ?  48  ARG B CZ  1 
ATOM   2063 N NH1 . ARG B 2 45  ? 154.267 125.125 145.314 1.00 60.56  1  48  ARG B NH1 1 
ATOM   2064 N NH2 . ARG B 2 45  ? 155.511 126.973 144.791 1.00 60.56  ?  48  ARG B NH2 1 
ATOM   2065 N N   . ARG B 2 46  ? 146.845 127.364 143.508 1.00 56.57  ?  49  ARG B N   1 
ATOM   2066 C CA  . ARG B 2 46  ? 145.438 127.090 143.266 1.00 56.57  ?  49  ARG B CA  1 
ATOM   2067 C C   . ARG B 2 46  ? 144.737 128.354 142.793 1.00 56.57  ?  49  ARG B C   1 
ATOM   2068 O O   . ARG B 2 46  ? 145.078 129.466 143.205 1.00 56.57  ?  49  ARG B O   1 
ATOM   2069 C CB  . ARG B 2 46  ? 144.736 126.562 144.525 1.00 56.57  ?  49  ARG B CB  1 
ATOM   2070 C CG  . ARG B 2 46  ? 145.383 125.339 145.146 1.00 56.57  ?  49  ARG B CG  1 
ATOM   2071 C CD  . ARG B 2 46  ? 145.080 124.087 144.345 1.00 56.57  ?  49  ARG B CD  1 
ATOM   2072 N NE  . ARG B 2 46  ? 145.256 122.877 145.139 1.00 56.57  ?  49  ARG B NE  1 
ATOM   2073 C CZ  . ARG B 2 46  ? 146.427 122.310 145.391 1.00 56.57  ?  49  ARG B CZ  1 
ATOM   2074 N NH1 . ARG B 2 46  ? 147.555 122.817 144.922 1.00 56.57  1  49  ARG B NH1 1 
ATOM   2075 N NH2 . ARG B 2 46  ? 146.468 121.207 146.131 1.00 56.57  ?  49  ARG B NH2 1 
ATOM   2076 N N   . THR B 2 47  ? 143.753 128.169 141.917 1.00 53.11  ?  50  THR B N   1 
ATOM   2077 C CA  . THR B 2 47  ? 142.875 129.244 141.474 1.00 53.11  ?  50  THR B CA  1 
ATOM   2078 C C   . THR B 2 47  ? 141.440 128.787 141.675 1.00 53.11  ?  50  THR B C   1 
ATOM   2079 O O   . THR B 2 47  ? 141.047 127.732 141.165 1.00 53.11  ?  50  THR B O   1 
ATOM   2080 C CB  . THR B 2 47  ? 143.125 129.607 140.008 1.00 53.11  ?  50  THR B CB  1 
ATOM   2081 O OG1 . THR B 2 47  ? 144.448 130.136 139.864 1.00 53.11  ?  50  THR B OG1 1 
ATOM   2082 C CG2 . THR B 2 47  ? 142.118 130.645 139.540 1.00 53.11  ?  50  THR B CG2 1 
ATOM   2083 N N   . LEU B 2 48  ? 140.663 129.572 142.412 1.00 51.85  ?  51  LEU B N   1 
ATOM   2084 C CA  . LEU B 2 48  ? 139.295 129.215 142.761 1.00 51.85  ?  51  LEU B CA  1 
ATOM   2085 C C   . LEU B 2 48  ? 138.330 129.997 141.879 1.00 51.85  ?  51  LEU B C   1 
ATOM   2086 O O   . LEU B 2 48  ? 138.278 131.230 141.949 1.00 51.85  ?  51  LEU B O   1 
ATOM   2087 C CB  . LEU B 2 48  ? 139.026 129.489 144.239 1.00 51.85  ?  51  LEU B CB  1 
ATOM   2088 C CG  . LEU B 2 48  ? 140.106 128.998 145.206 1.00 51.85  ?  51  LEU B CG  1 
ATOM   2089 C CD1 . LEU B 2 48  ? 139.783 129.408 146.631 1.00 51.85  ?  51  LEU B CD1 1 
ATOM   2090 C CD2 . LEU B 2 48  ? 140.271 127.492 145.107 1.00 51.85  ?  51  LEU B CD2 1 
ATOM   2091 N N   . ARG B 2 49  ? 137.568 129.280 141.060 1.00 58.03  ?  52  ARG B N   1 
ATOM   2092 C CA  . ARG B 2 49  ? 136.609 129.876 140.144 1.00 58.03  ?  52  ARG B CA  1 
ATOM   2093 C C   . ARG B 2 49  ? 135.194 129.456 140.519 1.00 58.03  ?  52  ARG B C   1 
ATOM   2094 O O   . ARG B 2 49  ? 134.965 128.345 141.003 1.00 58.03  ?  52  ARG B O   1 
ATOM   2095 C CB  . ARG B 2 49  ? 136.899 129.469 138.696 1.00 58.03  ?  52  ARG B CB  1 
ATOM   2096 C CG  . ARG B 2 49  ? 138.374 129.318 138.374 1.00 58.03  ?  52  ARG B CG  1 
ATOM   2097 C CD  . ARG B 2 49  ? 138.583 129.030 136.897 1.00 58.03  ?  52  ARG B CD  1 
ATOM   2098 N NE  . ARG B 2 49  ? 139.847 129.568 136.410 1.00 58.03  ?  52  ARG B NE  1 
ATOM   2099 C CZ  . ARG B 2 49  ? 141.008 128.931 136.479 1.00 58.03  ?  52  ARG B CZ  1 
ATOM   2100 N NH1 . ARG B 2 49  ? 141.102 127.723 137.010 1.00 58.03  1  52  ARG B NH1 1 
ATOM   2101 N NH2 . ARG B 2 49  ? 142.101 129.520 136.004 1.00 58.03  ?  52  ARG B NH2 1 
ATOM   2102 N N   . GLY B 2 50  ? 134.243 130.349 140.268 1.00 56.83  ?  53  GLY B N   1 
ATOM   2103 C CA  . GLY B 2 50  ? 132.863 130.105 140.630 1.00 56.83  ?  53  GLY B CA  1 
ATOM   2104 C C   . GLY B 2 50  ? 132.139 131.364 141.055 1.00 56.83  ?  53  GLY B C   1 
ATOM   2105 O O   . GLY B 2 50  ? 130.906 131.411 141.052 1.00 56.83  ?  53  GLY B O   1 
ATOM   2106 N N   . HIS B 2 51  ? 132.895 132.394 141.423 1.00 53.90  ?  54  HIS B N   1 
ATOM   2107 C CA  . HIS B 2 51  ? 132.312 133.702 141.675 1.00 53.90  ?  54  HIS B CA  1 
ATOM   2108 C C   . HIS B 2 51  ? 132.095 134.426 140.353 1.00 53.90  ?  54  HIS B C   1 
ATOM   2109 O O   . HIS B 2 51  ? 132.957 134.410 139.471 1.00 53.90  ?  54  HIS B O   1 
ATOM   2110 C CB  . HIS B 2 51  ? 133.216 134.531 142.587 1.00 53.90  ?  54  HIS B CB  1 
ATOM   2111 C CG  . HIS B 2 51  ? 133.051 134.226 144.043 1.00 53.90  ?  54  HIS B CG  1 
ATOM   2112 N ND1 . HIS B 2 51  ? 131.836 134.306 144.688 1.00 53.90  ?  54  HIS B ND1 1 
ATOM   2113 C CD2 . HIS B 2 51  ? 133.949 133.844 144.982 1.00 53.90  ?  54  HIS B CD2 1 
ATOM   2114 C CE1 . HIS B 2 51  ? 131.992 133.987 145.960 1.00 53.90  ?  54  HIS B CE1 1 
ATOM   2115 N NE2 . HIS B 2 51  ? 133.265 133.702 146.164 1.00 53.90  ?  54  HIS B NE2 1 
ATOM   2116 N N   . LEU B 2 52  ? 130.928 135.053 140.213 1.00 59.01  ?  55  LEU B N   1 
ATOM   2117 C CA  . LEU B 2 52  ? 130.555 135.732 138.979 1.00 59.01  ?  55  LEU B CA  1 
ATOM   2118 C C   . LEU B 2 52  ? 130.475 137.245 139.149 1.00 59.01  ?  55  LEU B C   1 
ATOM   2119 O O   . LEU B 2 52  ? 129.847 137.925 138.332 1.00 59.01  ?  55  LEU B O   1 
ATOM   2120 C CB  . LEU B 2 52  ? 129.230 135.178 138.457 1.00 59.01  ?  55  LEU B CB  1 
ATOM   2121 C CG  . LEU B 2 52  ? 129.294 133.701 138.063 1.00 59.01  ?  55  LEU B CG  1 
ATOM   2122 C CD1 . LEU B 2 52  ? 127.906 133.139 137.840 1.00 59.01  ?  55  LEU B CD1 1 
ATOM   2123 C CD2 . LEU B 2 52  ? 130.154 133.515 136.824 1.00 59.01  ?  55  LEU B CD2 1 
ATOM   2124 N N   . ALA B 2 53  ? 131.101 137.781 140.190 1.00 58.03  ?  56  ALA B N   1 
ATOM   2125 C CA  . ALA B 2 53  ? 131.142 139.218 140.421 1.00 58.03  ?  56  ALA B CA  1 
ATOM   2126 C C   . ALA B 2 53  ? 132.387 139.523 141.243 1.00 58.03  ?  56  ALA B C   1 
ATOM   2127 O O   . ALA B 2 53  ? 133.125 138.619 141.642 1.00 58.03  ?  56  ALA B O   1 
ATOM   2128 C CB  . ALA B 2 53  ? 129.869 139.708 141.114 1.00 58.03  ?  56  ALA B CB  1 
ATOM   2129 N N   . LYS B 2 54  ? 132.615 140.809 141.495 1.00 57.09  ?  57  LYS B N   1 
ATOM   2130 C CA  . LYS B 2 54  ? 133.801 141.223 142.233 1.00 57.09  ?  57  LYS B CA  1 
ATOM   2131 C C   . LYS B 2 54  ? 133.793 140.632 143.637 1.00 57.09  ?  57  LYS B C   1 
ATOM   2132 O O   . LYS B 2 54  ? 132.786 140.696 144.347 1.00 57.09  ?  57  LYS B O   1 
ATOM   2133 C CB  . LYS B 2 54  ? 133.873 142.748 142.302 1.00 57.09  ?  57  LYS B CB  1 
ATOM   2134 C CG  . LYS B 2 54  ? 133.555 143.441 140.990 1.00 57.09  ?  57  LYS B CG  1 
ATOM   2135 C CD  . LYS B 2 54  ? 134.066 144.871 140.981 1.00 57.09  ?  57  LYS B CD  1 
ATOM   2136 C CE  . LYS B 2 54  ? 133.103 145.811 141.683 1.00 57.09  ?  57  LYS B CE  1 
ATOM   2137 N NZ  . LYS B 2 54  ? 133.330 147.226 141.284 1.00 57.09  1  57  LYS B NZ  1 
ATOM   2138 N N   . ILE B 2 55  ? 134.922 140.054 144.032 1.00 53.11  ?  58  ILE B N   1 
ATOM   2139 C CA  . ILE B 2 55  ? 135.083 139.480 145.362 1.00 53.11  ?  58  ILE B CA  1 
ATOM   2140 C C   . ILE B 2 55  ? 135.521 140.589 146.305 1.00 53.11  ?  58  ILE B C   1 
ATOM   2141 O O   . ILE B 2 55  ? 136.551 141.234 146.080 1.00 53.11  ?  58  ILE B O   1 
ATOM   2142 C CB  . ILE B 2 55  ? 136.102 138.331 145.352 1.00 53.11  ?  58  ILE B CB  1 
ATOM   2143 C CG1 . ILE B 2 55  ? 135.557 137.141 144.565 1.00 53.11  ?  58  ILE B CG1 1 
ATOM   2144 C CG2 . ILE B 2 55  ? 136.453 137.920 146.770 1.00 53.11  ?  58  ILE B CG2 1 
ATOM   2145 C CD1 . ILE B 2 55  ? 136.568 136.045 144.358 1.00 53.11  ?  58  ILE B CD1 1 
ATOM   2146 N N   . TYR B 2 56  ? 134.746 140.816 147.365 1.00 57.19  ?  59  TYR B N   1 
ATOM   2147 C CA  . TYR B 2 56  ? 135.059 141.893 148.295 1.00 57.19  ?  59  TYR B CA  1 
ATOM   2148 C C   . TYR B 2 56  ? 135.651 141.429 149.616 1.00 57.19  ?  59  TYR B C   1 
ATOM   2149 O O   . TYR B 2 56  ? 136.185 142.262 150.356 1.00 57.19  ?  59  TYR B O   1 
ATOM   2150 C CB  . TYR B 2 56  ? 133.813 142.742 148.575 1.00 57.19  ?  59  TYR B CB  1 
ATOM   2151 C CG  . TYR B 2 56  ? 133.612 143.857 147.577 1.00 57.19  ?  59  TYR B CG  1 
ATOM   2152 C CD1 . TYR B 2 56  ? 133.025 143.624 146.345 1.00 57.19  ?  59  TYR B CD1 1 
ATOM   2153 C CD2 . TYR B 2 56  ? 134.045 145.145 147.862 1.00 57.19  ?  59  TYR B CD2 1 
ATOM   2154 C CE1 . TYR B 2 56  ? 132.858 144.647 145.432 1.00 57.19  ?  59  TYR B CE1 1 
ATOM   2155 C CE2 . TYR B 2 56  ? 133.877 146.171 146.959 1.00 57.19  ?  59  TYR B CE2 1 
ATOM   2156 C CZ  . TYR B 2 56  ? 133.283 145.917 145.746 1.00 57.19  ?  59  TYR B CZ  1 
ATOM   2157 O OH  . TYR B 2 56  ? 133.115 146.937 144.839 1.00 57.19  ?  59  TYR B OH  1 
ATOM   2158 N N   . ALA B 2 57  ? 135.586 140.141 149.935 1.00 52.59  ?  60  ALA B N   1 
ATOM   2159 C CA  . ALA B 2 57  ? 136.064 139.696 151.232 1.00 52.59  ?  60  ALA B CA  1 
ATOM   2160 C C   . ALA B 2 57  ? 136.506 138.244 151.158 1.00 52.59  ?  60  ALA B C   1 
ATOM   2161 O O   . ALA B 2 57  ? 136.181 137.517 150.217 1.00 52.59  ?  60  ALA B O   1 
ATOM   2162 C CB  . ALA B 2 57  ? 134.993 139.870 152.307 1.00 52.59  ?  60  ALA B CB  1 
ATOM   2163 N N   . MET B 2 58  ? 137.253 137.837 152.181 1.00 53.18  ?  61  MET B N   1 
ATOM   2164 C CA  . MET B 2 58  ? 137.799 136.493 152.283 1.00 53.18  ?  61  MET B CA  1 
ATOM   2165 C C   . MET B 2 58  ? 138.354 136.319 153.687 1.00 53.18  ?  61  MET B C   1 
ATOM   2166 O O   . MET B 2 58  ? 138.877 137.270 154.271 1.00 53.18  ?  61  MET B O   1 
ATOM   2167 C CB  . MET B 2 58  ? 138.889 136.258 151.231 1.00 53.18  ?  61  MET B CB  1 
ATOM   2168 C CG  . MET B 2 58  ? 139.493 134.866 151.194 1.00 53.18  ?  61  MET B CG  1 
ATOM   2169 S SD  . MET B 2 58  ? 140.771 134.635 152.440 1.00 53.18  ?  61  MET B SD  1 
ATOM   2170 C CE  . MET B 2 58  ? 142.065 135.639 151.733 1.00 53.18  ?  61  MET B CE  1 
ATOM   2171 N N   . HIS B 2 59  ? 138.234 135.108 154.223 1.00 47.92  ?  62  HIS B N   1 
ATOM   2172 C CA  . HIS B 2 59  ? 138.786 134.808 155.537 1.00 47.92  ?  62  HIS B CA  1 
ATOM   2173 C C   . HIS B 2 59  ? 139.173 133.340 155.594 1.00 47.92  ?  62  HIS B C   1 
ATOM   2174 O O   . HIS B 2 59  ? 138.372 132.471 155.241 1.00 47.92  ?  62  HIS B O   1 
ATOM   2175 C CB  . HIS B 2 59  ? 137.786 135.141 156.648 1.00 47.92  ?  62  HIS B CB  1 
ATOM   2176 C CG  . HIS B 2 59  ? 138.423 135.364 157.984 1.00 47.92  ?  62  HIS B CG  1 
ATOM   2177 N ND1 . HIS B 2 59  ? 138.103 134.617 159.096 1.00 47.92  ?  62  HIS B ND1 1 
ATOM   2178 C CD2 . HIS B 2 59  ? 139.367 136.247 158.384 1.00 47.92  ?  62  HIS B CD2 1 
ATOM   2179 C CE1 . HIS B 2 59  ? 138.819 135.032 160.125 1.00 47.92  ?  62  HIS B CE1 1 
ATOM   2180 N NE2 . HIS B 2 59  ? 139.595 136.021 159.719 1.00 47.92  ?  62  HIS B NE2 1 
ATOM   2181 N N   . TRP B 2 60  ? 140.397 133.073 156.037 1.00 50.75  ?  63  TRP B N   1 
ATOM   2182 C CA  . TRP B 2 60  ? 140.875 131.709 156.190 1.00 50.75  ?  63  TRP B CA  1 
ATOM   2183 C C   . TRP B 2 60  ? 140.277 131.059 157.431 1.00 50.75  ?  63  TRP B C   1 
ATOM   2184 O O   . TRP B 2 60  ? 139.921 131.731 158.402 1.00 50.75  ?  63  TRP B O   1 
ATOM   2185 C CB  . TRP B 2 60  ? 142.399 131.677 156.292 1.00 50.75  ?  63  TRP B CB  1 
ATOM   2186 C CG  . TRP B 2 60  ? 143.113 131.699 154.982 1.00 50.75  ?  63  TRP B CG  1 
ATOM   2187 C CD1 . TRP B 2 60  ? 143.726 132.766 154.401 1.00 50.75  ?  63  TRP B CD1 1 
ATOM   2188 C CD2 . TRP B 2 60  ? 143.311 130.591 154.098 1.00 50.75  ?  63  TRP B CD2 1 
ATOM   2189 N NE1 . TRP B 2 60  ? 144.287 132.396 153.205 1.00 50.75  ?  63  TRP B NE1 1 
ATOM   2190 C CE2 . TRP B 2 60  ? 144.045 131.064 152.995 1.00 50.75  ?  63  TRP B CE2 1 
ATOM   2191 C CE3 . TRP B 2 60  ? 142.935 129.246 154.130 1.00 50.75  ?  63  TRP B CE3 1 
ATOM   2192 C CZ2 . TRP B 2 60  ? 144.411 130.241 151.935 1.00 50.75  ?  63  TRP B CZ2 1 
ATOM   2193 C CZ3 . TRP B 2 60  ? 143.298 128.432 153.076 1.00 50.75  ?  63  TRP B CZ3 1 
ATOM   2194 C CH2 . TRP B 2 60  ? 144.028 128.931 151.994 1.00 50.75  ?  63  TRP B CH2 1 
ATOM   2195 N N   . GLY B 2 61  ? 140.171 129.734 157.388 1.00 56.61  ?  64  GLY B N   1 
ATOM   2196 C CA  . GLY B 2 61  ? 139.804 128.990 158.569 1.00 56.61  ?  64  GLY B CA  1 
ATOM   2197 C C   . GLY B 2 61  ? 140.990 128.738 159.478 1.00 56.61  ?  64  GLY B C   1 
ATOM   2198 O O   . GLY B 2 61  ? 142.148 128.834 159.078 1.00 56.61  ?  64  GLY B O   1 
ATOM   2199 N N   . THR B 2 62  ? 140.688 128.409 160.735 1.00 61.03  ?  65  THR B N   1 
ATOM   2200 C CA  . THR B 2 62  ? 141.749 128.093 161.682 1.00 61.03  ?  65  THR B CA  1 
ATOM   2201 C C   . THR B 2 62  ? 142.437 126.771 161.375 1.00 61.03  ?  65  THR B C   1 
ATOM   2202 O O   . THR B 2 62  ? 143.529 126.526 161.899 1.00 61.03  ?  65  THR B O   1 
ATOM   2203 C CB  . THR B 2 62  ? 141.200 128.073 163.108 1.00 61.03  ?  65  THR B CB  1 
ATOM   2204 O OG1 . THR B 2 62  ? 140.044 127.229 163.166 1.00 61.03  ?  65  THR B OG1 1 
ATOM   2205 C CG2 . THR B 2 62  ? 140.830 129.477 163.549 1.00 61.03  ?  65  THR B CG2 1 
ATOM   2206 N N   . ASP B 2 63  ? 141.835 125.921 160.547 1.00 60.58  ?  66  ASP B N   1 
ATOM   2207 C CA  . ASP B 2 63  ? 142.482 124.694 160.104 1.00 60.58  ?  66  ASP B CA  1 
ATOM   2208 C C   . ASP B 2 63  ? 143.375 124.909 158.891 1.00 60.58  ?  66  ASP B C   1 
ATOM   2209 O O   . ASP B 2 63  ? 143.991 123.947 158.421 1.00 60.58  ?  66  ASP B O   1 
ATOM   2210 C CB  . ASP B 2 63  ? 141.431 123.627 159.789 1.00 60.58  ?  66  ASP B CB  1 
ATOM   2211 C CG  . ASP B 2 63  ? 140.412 124.094 158.769 1.00 60.58  ?  66  ASP B CG  1 
ATOM   2212 O OD1 . ASP B 2 63  ? 140.349 125.312 158.503 1.00 60.58  ?  66  ASP B OD1 1 
ATOM   2213 O OD2 . ASP B 2 63  ? 139.674 123.242 158.233 1.00 60.58  -1 66  ASP B OD2 1 
ATOM   2214 N N   . SER B 2 64  ? 143.443 126.136 158.372 1.00 57.35  ?  67  SER B N   1 
ATOM   2215 C CA  . SER B 2 64  ? 144.286 126.502 157.236 1.00 57.35  ?  67  SER B CA  1 
ATOM   2216 C C   . SER B 2 64  ? 143.913 125.747 155.967 1.00 57.35  ?  67  SER B C   1 
ATOM   2217 O O   . SER B 2 64  ? 144.735 125.619 155.055 1.00 57.35  ?  67  SER B O   1 
ATOM   2218 C CB  . SER B 2 64  ? 145.771 126.293 157.555 1.00 57.35  ?  67  SER B CB  1 
ATOM   2219 O OG  . SER B 2 64  ? 146.142 126.995 158.728 1.00 57.35  ?  67  SER B OG  1 
ATOM   2220 N N   . ARG B 2 65  ? 142.694 125.244 155.887 1.00 53.54  ?  68  ARG B N   1 
ATOM   2221 C CA  . ARG B 2 65  ? 142.255 124.497 154.716 1.00 53.54  ?  68  ARG B CA  1 
ATOM   2222 C C   . ARG B 2 65  ? 140.983 125.056 154.096 1.00 53.54  ?  68  ARG B C   1 
ATOM   2223 O O   . ARG B 2 65  ? 140.874 125.099 152.869 1.00 53.54  ?  68  ARG B O   1 
ATOM   2224 C CB  . ARG B 2 65  ? 142.055 123.020 155.094 1.00 53.54  ?  68  ARG B CB  1 
ATOM   2225 C CG  . ARG B 2 65  ? 141.353 122.192 154.039 1.00 53.54  ?  68  ARG B CG  1 
ATOM   2226 C CD  . ARG B 2 65  ? 141.929 120.791 153.970 1.00 53.54  ?  68  ARG B CD  1 
ATOM   2227 N NE  . ARG B 2 65  ? 141.403 120.043 152.835 1.00 53.54  ?  68  ARG B NE  1 
ATOM   2228 C CZ  . ARG B 2 65  ? 141.608 118.749 152.633 1.00 53.54  ?  68  ARG B CZ  1 
ATOM   2229 N NH1 . ARG B 2 65  ? 142.326 118.024 153.475 1.00 53.54  1  68  ARG B NH1 1 
ATOM   2230 N NH2 . ARG B 2 65  ? 141.079 118.168 151.561 1.00 53.54  ?  68  ARG B NH2 1 
ATOM   2231 N N   . LEU B 2 66  ? 140.029 125.498 154.908 1.00 49.21  ?  69  LEU B N   1 
ATOM   2232 C CA  . LEU B 2 66  ? 138.776 126.055 154.421 1.00 49.21  ?  69  LEU B CA  1 
ATOM   2233 C C   . LEU B 2 66  ? 138.839 127.575 154.448 1.00 49.21  ?  69  LEU B C   1 
ATOM   2234 O O   . LEU B 2 66  ? 139.443 128.164 155.349 1.00 49.21  ?  69  LEU B O   1 
ATOM   2235 C CB  . LEU B 2 66  ? 137.598 125.572 155.267 1.00 49.21  ?  69  LEU B CB  1 
ATOM   2236 C CG  . LEU B 2 66  ? 137.319 124.071 155.246 1.00 49.21  ?  69  LEU B CG  1 
ATOM   2237 C CD1 . LEU B 2 66  ? 136.214 123.719 156.225 1.00 49.21  ?  69  LEU B CD1 1 
ATOM   2238 C CD2 . LEU B 2 66  ? 136.955 123.631 153.846 1.00 49.21  ?  69  LEU B CD2 1 
ATOM   2239 N N   . LEU B 2 67  ? 138.213 128.208 153.458 1.00 48.56  ?  70  LEU B N   1 
ATOM   2240 C CA  . LEU B 2 67  ? 138.185 129.665 153.409 1.00 48.56  ?  70  LEU B CA  1 
ATOM   2241 C C   . LEU B 2 67  ? 136.851 130.147 152.860 1.00 48.56  ?  70  LEU B C   1 
ATOM   2242 O O   . LEU B 2 67  ? 136.310 129.557 151.927 1.00 48.56  ?  70  LEU B O   1 
ATOM   2243 C CB  . LEU B 2 67  ? 139.347 130.218 152.566 1.00 48.56  ?  70  LEU B CB  1 
ATOM   2244 C CG  . LEU B 2 67  ? 139.421 129.931 151.064 1.00 48.56  ?  70  LEU B CG  1 
ATOM   2245 C CD1 . LEU B 2 67  ? 138.711 131.004 150.253 1.00 48.56  ?  70  LEU B CD1 1 
ATOM   2246 C CD2 . LEU B 2 67  ? 140.864 129.798 150.619 1.00 48.56  ?  70  LEU B CD2 1 
ATOM   2247 N N   . VAL B 2 68  ? 136.333 131.232 153.424 1.00 48.86  ?  71  VAL B N   1 
ATOM   2248 C CA  . VAL B 2 68  ? 135.048 131.790 153.021 1.00 48.86  ?  71  VAL B CA  1 
ATOM   2249 C C   . VAL B 2 68  ? 135.295 133.071 152.237 1.00 48.86  ?  71  VAL B C   1 
ATOM   2250 O O   . VAL B 2 68  ? 136.144 133.886 152.614 1.00 48.86  ?  71  VAL B O   1 
ATOM   2251 C CB  . VAL B 2 68  ? 134.138 132.044 154.240 1.00 48.86  ?  71  VAL B CB  1 
ATOM   2252 C CG1 . VAL B 2 68  ? 134.841 132.915 155.265 1.00 48.86  ?  71  VAL B CG1 1 
ATOM   2253 C CG2 . VAL B 2 68  ? 132.830 132.671 153.810 1.00 48.86  ?  71  VAL B CG2 1 
ATOM   2254 N N   . SER B 2 69  ? 134.572 133.235 151.130 1.00 49.06  ?  72  SER B N   1 
ATOM   2255 C CA  . SER B 2 69  ? 134.686 134.418 150.290 1.00 49.06  ?  72  SER B CA  1 
ATOM   2256 C C   . SER B 2 69  ? 133.302 134.960 149.966 1.00 49.06  ?  72  SER B C   1 
ATOM   2257 O O   . SER B 2 69  ? 132.334 134.205 149.856 1.00 49.06  ?  72  SER B O   1 
ATOM   2258 C CB  . SER B 2 69  ? 135.438 134.117 148.993 1.00 49.06  ?  72  SER B CB  1 
ATOM   2259 O OG  . SER B 2 69  ? 134.640 133.352 148.110 1.00 49.06  ?  72  SER B OG  1 
ATOM   2260 N N   . ALA B 2 70  ? 133.219 136.279 149.809 1.00 51.67  ?  73  ALA B N   1 
ATOM   2261 C CA  . ALA B 2 70  ? 131.963 136.970 149.548 1.00 51.67  ?  73  ALA B CA  1 
ATOM   2262 C C   . ALA B 2 70  ? 132.075 137.771 148.261 1.00 51.67  ?  73  ALA B C   1 
ATOM   2263 O O   . ALA B 2 70  ? 133.071 138.475 148.047 1.00 51.67  ?  73  ALA B O   1 
ATOM   2264 C CB  . ALA B 2 70  ? 131.596 137.895 150.709 1.00 51.67  ?  73  ALA B CB  1 
ATOM   2265 N N   . SER B 2 71  ? 131.052 137.678 147.411 1.00 55.54  ?  74  SER B N   1 
ATOM   2266 C CA  . SER B 2 71  ? 131.048 138.423 146.160 1.00 55.54  ?  74  SER B CA  1 
ATOM   2267 C C   . SER B 2 71  ? 129.732 139.168 145.992 1.00 55.54  ?  74  SER B C   1 
ATOM   2268 O O   . SER B 2 71  ? 128.725 138.851 146.629 1.00 55.54  ?  74  SER B O   1 
ATOM   2269 C CB  . SER B 2 71  ? 131.290 137.509 144.954 1.00 55.54  ?  74  SER B CB  1 
ATOM   2270 O OG  . SER B 2 71  ? 130.434 136.382 144.991 1.00 55.54  ?  74  SER B OG  1 
ATOM   2271 N N   . GLN B 2 72  ? 129.756 140.171 145.109 1.00 61.35  ?  75  GLN B N   1 
ATOM   2272 C CA  . GLN B 2 72  ? 128.584 140.999 144.849 1.00 61.35  ?  75  GLN B CA  1 
ATOM   2273 C C   . GLN B 2 72  ? 127.464 140.245 144.151 1.00 61.35  ?  75  GLN B C   1 
ATOM   2274 O O   . GLN B 2 72  ? 126.351 140.773 144.064 1.00 61.35  ?  75  GLN B O   1 
ATOM   2275 C CB  . GLN B 2 72  ? 128.967 142.216 144.010 1.00 61.35  ?  75  GLN B CB  1 
ATOM   2276 C CG  . GLN B 2 72  ? 129.936 143.151 144.691 1.00 61.35  ?  75  GLN B CG  1 
ATOM   2277 C CD  . GLN B 2 72  ? 129.356 143.788 145.937 1.00 61.35  ?  75  GLN B CD  1 
ATOM   2278 O OE1 . GLN B 2 72  ? 128.506 144.672 145.857 1.00 61.35  ?  75  GLN B OE1 1 
ATOM   2279 N NE2 . GLN B 2 72  ? 129.818 143.342 147.097 1.00 61.35  ?  75  GLN B NE2 1 
ATOM   2280 N N   . ASP B 2 73  ? 127.721 139.043 143.655 1.00 60.68  ?  76  ASP B N   1 
ATOM   2281 C CA  . ASP B 2 73  ? 126.655 138.247 143.060 1.00 60.68  ?  76  ASP B CA  1 
ATOM   2282 C C   . ASP B 2 73  ? 125.726 137.646 144.100 1.00 60.68  ?  76  ASP B C   1 
ATOM   2283 O O   . ASP B 2 73  ? 124.919 136.772 143.762 1.00 60.68  ?  76  ASP B O   1 
ATOM   2284 C CB  . ASP B 2 73  ? 127.251 137.146 142.181 1.00 60.68  ?  76  ASP B CB  1 
ATOM   2285 C CG  . ASP B 2 73  ? 127.999 136.101 142.980 1.00 60.68  ?  76  ASP B CG  1 
ATOM   2286 O OD1 . ASP B 2 73  ? 128.426 136.408 144.111 1.00 60.68  ?  76  ASP B OD1 1 
ATOM   2287 O OD2 . ASP B 2 73  ? 128.165 134.970 142.478 1.00 60.68  -1 76  ASP B OD2 1 
ATOM   2288 N N   . GLY B 2 74  ? 125.829 138.094 145.349 1.00 57.73  ?  77  GLY B N   1 
ATOM   2289 C CA  . GLY B 2 74  ? 124.996 137.574 146.410 1.00 57.73  ?  77  GLY B CA  1 
ATOM   2290 C C   . GLY B 2 74  ? 125.408 136.220 146.926 1.00 57.73  ?  77  GLY B C   1 
ATOM   2291 O O   . GLY B 2 74  ? 124.567 135.495 147.465 1.00 57.73  ?  77  GLY B O   1 
ATOM   2292 N N   . LYS B 2 75  ? 126.676 135.850 146.779 1.00 54.99  ?  78  LYS B N   1 
ATOM   2293 C CA  . LYS B 2 75  ? 127.137 134.517 147.130 1.00 54.99  ?  78  LYS B CA  1 
ATOM   2294 C C   . LYS B 2 75  ? 128.264 134.577 148.151 1.00 54.99  ?  78  LYS B C   1 
ATOM   2295 O O   . LYS B 2 75  ? 129.186 135.402 148.046 1.00 54.99  ?  78  LYS B O   1 
ATOM   2296 C CB  . LYS B 2 75  ? 127.597 133.749 145.888 1.00 54.99  ?  78  LYS B CB  1 
ATOM   2297 C CG  . LYS B 2 75  ? 126.448 133.279 145.014 1.00 54.99  ?  78  LYS B CG  1 
ATOM   2298 C CD  . LYS B 2 75  ? 125.497 132.388 145.795 1.00 54.99  ?  78  LYS B CD  1 
ATOM   2299 C CE  . LYS B 2 75  ? 124.351 131.904 144.924 1.00 54.99  ?  78  LYS B CE  1 
ATOM   2300 N NZ  . LYS B 2 75  ? 123.466 133.021 144.497 1.00 54.99  1  78  LYS B NZ  1 
ATOM   2301 N N   . LEU B 2 76  ? 128.171 133.683 149.134 1.00 49.88  ?  79  LEU B N   1 
ATOM   2302 C CA  . LEU B 2 76  ? 129.196 133.457 150.148 1.00 49.88  ?  79  LEU B CA  1 
ATOM   2303 C C   . LEU B 2 76  ? 129.637 132.006 149.989 1.00 49.88  ?  79  LEU B C   1 
ATOM   2304 O O   . LEU B 2 76  ? 128.916 131.086 150.382 1.00 49.88  ?  79  LEU B O   1 
ATOM   2305 C CB  . LEU B 2 76  ? 128.645 133.732 151.544 1.00 49.88  ?  79  LEU B CB  1 
ATOM   2306 C CG  . LEU B 2 76  ? 129.616 133.877 152.712 1.00 49.88  ?  79  LEU B CG  1 
ATOM   2307 C CD1 . LEU B 2 76  ? 130.236 135.257 152.721 1.00 49.88  ?  79  LEU B CD1 1 
ATOM   2308 C CD2 . LEU B 2 76  ? 128.905 133.604 154.023 1.00 49.88  ?  79  LEU B CD2 1 
ATOM   2309 N N   . ILE B 2 77  ? 130.805 131.792 149.399 1.00 48.49  ?  80  ILE B N   1 
ATOM   2310 C CA  . ILE B 2 77  ? 131.270 130.451 149.061 1.00 48.49  ?  80  ILE B CA  1 
ATOM   2311 C C   . ILE B 2 77  ? 132.326 130.019 150.066 1.00 48.49  ?  80  ILE B C   1 
ATOM   2312 O O   . ILE B 2 77  ? 133.281 130.758 150.335 1.00 48.49  ?  80  ILE B O   1 
ATOM   2313 C CB  . ILE B 2 77  ? 131.820 130.392 147.627 1.00 48.49  ?  80  ILE B CB  1 
ATOM   2314 C CG1 . ILE B 2 77  ? 130.743 130.809 146.627 1.00 48.49  ?  80  ILE B CG1 1 
ATOM   2315 C CG2 . ILE B 2 77  ? 132.306 128.993 147.306 1.00 48.49  ?  80  ILE B CG2 1 
ATOM   2316 C CD1 . ILE B 2 77  ? 131.181 130.702 145.188 1.00 48.49  ?  80  ILE B CD1 1 
ATOM   2317 N N   . ILE B 2 78  ? 132.152 128.824 150.619 1.00 47.52  ?  81  ILE B N   1 
ATOM   2318 C CA  . ILE B 2 78  ? 133.128 128.204 151.504 1.00 47.52  ?  81  ILE B CA  1 
ATOM   2319 C C   . ILE B 2 78  ? 133.874 127.160 150.688 1.00 47.52  ?  81  ILE B C   1 
ATOM   2320 O O   . ILE B 2 78  ? 133.281 126.175 150.229 1.00 47.52  ?  81  ILE B O   1 
ATOM   2321 C CB  . ILE B 2 78  ? 132.464 127.585 152.740 1.00 47.52  ?  81  ILE B CB  1 
ATOM   2322 C CG1 . ILE B 2 78  ? 131.910 128.684 153.643 1.00 47.52  ?  81  ILE B CG1 1 
ATOM   2323 C CG2 . ILE B 2 78  ? 133.457 126.727 153.501 1.00 47.52  ?  81  ILE B CG2 1 
ATOM   2324 C CD1 . ILE B 2 78  ? 130.808 128.220 154.547 1.00 47.52  ?  81  ILE B CD1 1 
ATOM   2325 N N   . TRP B 2 79  ? 135.178 127.385 150.540 1.00 50.09  ?  82  TRP B N   1 
ATOM   2326 C CA  . TRP B 2 79  ? 136.070 126.666 149.648 1.00 50.09  ?  82  TRP B CA  1 
ATOM   2327 C C   . TRP B 2 79  ? 136.950 125.720 150.449 1.00 50.09  ?  82  TRP B C   1 
ATOM   2328 O O   . TRP B 2 79  ? 137.440 126.078 151.527 1.00 50.09  ?  82  TRP B O   1 
ATOM   2329 C CB  . TRP B 2 79  ? 136.989 127.640 148.909 1.00 50.09  ?  82  TRP B CB  1 
ATOM   2330 C CG  . TRP B 2 79  ? 136.331 128.621 148.009 1.00 50.09  ?  82  TRP B CG  1 
ATOM   2331 C CD1 . TRP B 2 79  ? 135.885 129.864 148.345 1.00 50.09  ?  82  TRP B CD1 1 
ATOM   2332 C CD2 . TRP B 2 79  ? 136.119 128.487 146.602 1.00 50.09  ?  82  TRP B CD2 1 
ATOM   2333 N NE1 . TRP B 2 79  ? 135.368 130.496 147.244 1.00 50.09  ?  82  TRP B NE1 1 
ATOM   2334 C CE2 . TRP B 2 79  ? 135.504 129.673 146.159 1.00 50.09  ?  82  TRP B CE2 1 
ATOM   2335 C CE3 . TRP B 2 79  ? 136.371 127.472 145.677 1.00 50.09  ?  82  TRP B CE3 1 
ATOM   2336 C CZ2 . TRP B 2 79  ? 135.137 129.871 144.835 1.00 50.09  ?  82  TRP B CZ2 1 
ATOM   2337 C CZ3 . TRP B 2 79  ? 136.007 127.671 144.364 1.00 50.09  ?  82  TRP B CZ3 1 
ATOM   2338 C CH2 . TRP B 2 79  ? 135.400 128.862 143.954 1.00 50.09  ?  82  TRP B CH2 1 
ATOM   2339 N N   . ASP B 2 80  ? 137.174 124.530 149.898 1.00 52.21  ?  83  ASP B N   1 
ATOM   2340 C CA  . ASP B 2 80  ? 138.240 123.641 150.345 1.00 52.21  ?  83  ASP B CA  1 
ATOM   2341 C C   . ASP B 2 80  ? 139.477 123.965 149.515 1.00 52.21  ?  83  ASP B C   1 
ATOM   2342 O O   . ASP B 2 80  ? 139.573 123.562 148.352 1.00 52.21  ?  83  ASP B O   1 
ATOM   2343 C CB  . ASP B 2 80  ? 137.827 122.181 150.188 1.00 52.21  ?  83  ASP B CB  1 
ATOM   2344 C CG  . ASP B 2 80  ? 138.917 121.213 150.605 1.00 52.21  ?  83  ASP B CG  1 
ATOM   2345 O OD1 . ASP B 2 80  ? 139.887 121.642 151.260 1.00 52.21  ?  83  ASP B OD1 1 
ATOM   2346 O OD2 . ASP B 2 80  ? 138.803 120.015 150.273 1.00 52.21  -1 83  ASP B OD2 1 
ATOM   2347 N N   . SER B 2 81  ? 140.423 124.694 150.111 1.00 53.59  ?  84  SER B N   1 
ATOM   2348 C CA  . SER B 2 81  ? 141.544 125.227 149.342 1.00 53.59  ?  84  SER B CA  1 
ATOM   2349 C C   . SER B 2 81  ? 142.456 124.129 148.810 1.00 53.59  ?  84  SER B C   1 
ATOM   2350 O O   . SER B 2 81  ? 143.068 124.299 147.750 1.00 53.59  ?  84  SER B O   1 
ATOM   2351 C CB  . SER B 2 81  ? 142.345 126.208 150.196 1.00 53.59  ?  84  SER B CB  1 
ATOM   2352 O OG  . SER B 2 81  ? 142.661 125.643 151.455 1.00 53.59  ?  84  SER B OG  1 
ATOM   2353 N N   . TYR B 2 82  ? 142.569 123.008 149.526 1.00 55.18  ?  85  TYR B N   1 
ATOM   2354 C CA  . TYR B 2 82  ? 143.479 121.949 149.097 1.00 55.18  ?  85  TYR B CA  1 
ATOM   2355 C C   . TYR B 2 82  ? 143.045 121.346 147.767 1.00 55.18  ?  85  TYR B C   1 
ATOM   2356 O O   . TYR B 2 82  ? 143.881 121.084 146.894 1.00 55.18  ?  85  TYR B O   1 
ATOM   2357 C CB  . TYR B 2 82  ? 143.566 120.862 150.168 1.00 55.18  ?  85  TYR B CB  1 
ATOM   2358 C CG  . TYR B 2 82  ? 144.447 121.206 151.350 1.00 55.18  ?  85  TYR B CG  1 
ATOM   2359 C CD1 . TYR B 2 82  ? 144.719 122.525 151.683 1.00 55.18  ?  85  TYR B CD1 1 
ATOM   2360 C CD2 . TYR B 2 82  ? 145.001 120.207 152.137 1.00 55.18  ?  85  TYR B CD2 1 
ATOM   2361 C CE1 . TYR B 2 82  ? 145.519 122.838 152.762 1.00 55.18  ?  85  TYR B CE1 1 
ATOM   2362 C CE2 . TYR B 2 82  ? 145.802 120.511 153.218 1.00 55.18  ?  85  TYR B CE2 1 
ATOM   2363 C CZ  . TYR B 2 82  ? 146.057 121.828 153.527 1.00 55.18  ?  85  TYR B CZ  1 
ATOM   2364 O OH  . TYR B 2 82  ? 146.856 122.135 154.603 1.00 55.18  ?  85  TYR B OH  1 
ATOM   2365 N N   . THR B 2 83  ? 141.745 121.117 147.592 1.00 52.09  ?  86  THR B N   1 
ATOM   2366 C CA  . THR B 2 83  ? 141.220 120.477 146.395 1.00 52.09  ?  86  THR B CA  1 
ATOM   2367 C C   . THR B 2 83  ? 140.358 121.400 145.546 1.00 52.09  ?  86  THR B C   1 
ATOM   2368 O O   . THR B 2 83  ? 139.757 120.935 144.572 1.00 52.09  ?  86  THR B O   1 
ATOM   2369 C CB  . THR B 2 83  ? 140.408 119.232 146.772 1.00 52.09  ?  86  THR B CB  1 
ATOM   2370 O OG1 . THR B 2 83  ? 139.109 119.628 147.226 1.00 52.09  ?  86  THR B OG1 1 
ATOM   2371 C CG2 . THR B 2 83  ? 141.107 118.454 147.874 1.00 52.09  ?  86  THR B CG2 1 
ATOM   2372 N N   . THR B 2 84  ? 140.273 122.686 145.891 1.00 53.43  ?  87  THR B N   1 
ATOM   2373 C CA  . THR B 2 84  ? 139.455 123.676 145.186 1.00 53.43  ?  87  THR B CA  1 
ATOM   2374 C C   . THR B 2 84  ? 137.977 123.299 145.154 1.00 53.43  ?  87  THR B C   1 
ATOM   2375 O O   . THR B 2 84  ? 137.214 123.840 144.348 1.00 53.43  ?  87  THR B O   1 
ATOM   2376 C CB  . THR B 2 84  ? 139.962 123.920 143.759 1.00 53.43  ?  87  THR B CB  1 
ATOM   2377 O OG1 . THR B 2 84  ? 139.660 122.785 142.939 1.00 53.43  ?  87  THR B OG1 1 
ATOM   2378 C CG2 . THR B 2 84  ? 141.462 124.158 143.758 1.00 53.43  ?  87  THR B CG2 1 
ATOM   2379 N N   . ASN B 2 85  ? 137.554 122.378 146.015 1.00 52.86  ?  88  ASN B N   1 
ATOM   2380 C CA  . ASN B 2 85  ? 136.153 121.993 146.070 1.00 52.86  ?  88  ASN B CA  1 
ATOM   2381 C C   . ASN B 2 85  ? 135.329 123.066 146.772 1.00 52.86  ?  88  ASN B C   1 
ATOM   2382 O O   . ASN B 2 85  ? 135.793 123.729 147.703 1.00 52.86  ?  88  ASN B O   1 
ATOM   2383 C CB  . ASN B 2 85  ? 135.991 120.659 146.796 1.00 52.86  ?  88  ASN B CB  1 
ATOM   2384 C CG  . ASN B 2 85  ? 136.276 119.473 145.903 1.00 52.86  ?  88  ASN B CG  1 
ATOM   2385 O OD1 . ASN B 2 85  ? 136.962 118.533 146.302 1.00 52.86  ?  88  ASN B OD1 1 
ATOM   2386 N ND2 . ASN B 2 85  ? 135.751 119.510 144.686 1.00 52.86  ?  88  ASN B ND2 1 
ATOM   2387 N N   . LYS B 2 86  ? 134.092 123.230 146.316 1.00 52.68  ?  89  LYS B N   1 
ATOM   2388 C CA  . LYS B 2 86  ? 133.153 124.161 146.936 1.00 52.68  ?  89  LYS B CA  1 
ATOM   2389 C C   . LYS B 2 86  ? 132.413 123.416 148.037 1.00 52.68  ?  89  LYS B C   1 
ATOM   2390 O O   . LYS B 2 86  ? 131.476 122.661 147.771 1.00 52.68  ?  89  LYS B O   1 
ATOM   2391 C CB  . LYS B 2 86  ? 132.189 124.730 145.903 1.00 52.68  ?  89  LYS B CB  1 
ATOM   2392 C CG  . LYS B 2 86  ? 132.851 125.594 144.854 1.00 52.68  ?  89  LYS B CG  1 
ATOM   2393 C CD  . LYS B 2 86  ? 131.843 126.514 144.202 1.00 52.68  ?  89  LYS B CD  1 
ATOM   2394 C CE  . LYS B 2 86  ? 132.485 127.335 143.106 1.00 52.68  ?  89  LYS B CE  1 
ATOM   2395 N NZ  . LYS B 2 86  ? 133.227 126.479 142.143 1.00 52.68  1  89  LYS B NZ  1 
ATOM   2396 N N   . VAL B 2 87  ? 132.842 123.622 149.281 1.00 48.72  ?  90  VAL B N   1 
ATOM   2397 C CA  . VAL B 2 87  ? 132.183 122.970 150.407 1.00 48.72  ?  90  VAL B CA  1 
ATOM   2398 C C   . VAL B 2 87  ? 130.776 123.521 150.590 1.00 48.72  ?  90  VAL B C   1 
ATOM   2399 O O   . VAL B 2 87  ? 129.819 122.767 150.801 1.00 48.72  ?  90  VAL B O   1 
ATOM   2400 C CB  . VAL B 2 87  ? 133.021 123.126 151.687 1.00 48.72  ?  90  VAL B CB  1 
ATOM   2401 C CG1 . VAL B 2 87  ? 132.403 122.332 152.822 1.00 48.72  ?  90  VAL B CG1 1 
ATOM   2402 C CG2 . VAL B 2 87  ? 134.443 122.674 151.435 1.00 48.72  ?  90  VAL B CG2 1 
ATOM   2403 N N   . HIS B 2 88  ? 130.624 124.841 150.510 1.00 49.75  ?  91  HIS B N   1 
ATOM   2404 C CA  . HIS B 2 88  ? 129.320 125.455 150.727 1.00 49.75  ?  91  HIS B CA  1 
ATOM   2405 C C   . HIS B 2 88  ? 129.131 126.639 149.792 1.00 49.75  ?  91  HIS B C   1 
ATOM   2406 O O   . HIS B 2 88  ? 130.098 127.268 149.360 1.00 49.75  ?  91  HIS B O   1 
ATOM   2407 C CB  . HIS B 2 88  ? 129.146 125.920 152.179 1.00 49.75  ?  91  HIS B CB  1 
ATOM   2408 C CG  . HIS B 2 88  ? 128.839 124.814 153.139 1.00 49.75  ?  91  HIS B CG  1 
ATOM   2409 N ND1 . HIS B 2 88  ? 127.643 124.129 153.128 1.00 49.75  ?  91  HIS B ND1 1 
ATOM   2410 C CD2 . HIS B 2 88  ? 129.570 124.279 154.146 1.00 49.75  ?  91  HIS B CD2 1 
ATOM   2411 C CE1 . HIS B 2 88  ? 127.652 123.218 154.084 1.00 49.75  ?  91  HIS B CE1 1 
ATOM   2412 N NE2 . HIS B 2 88  ? 128.809 123.288 154.716 1.00 49.75  ?  91  HIS B NE2 1 
ATOM   2413 N N   . ALA B 2 89  ? 127.868 126.952 149.507 1.00 48.44  ?  92  ALA B N   1 
ATOM   2414 C CA  . ALA B 2 89  ? 127.505 128.138 148.730 1.00 48.44  ?  92  ALA B CA  1 
ATOM   2415 C C   . ALA B 2 89  ? 126.230 128.709 149.342 1.00 48.44  ?  92  ALA B C   1 
ATOM   2416 O O   . ALA B 2 89  ? 125.141 128.166 149.137 1.00 48.44  ?  92  ALA B O   1 
ATOM   2417 C CB  . ALA B 2 89  ? 127.314 127.806 147.256 1.00 48.44  ?  92  ALA B CB  1 
ATOM   2418 N N   . ILE B 2 90  ? 126.368 129.795 150.091 1.00 50.76  ?  93  ILE B N   1 
ATOM   2419 C CA  . ILE B 2 90  ? 125.259 130.421 150.803 1.00 50.76  ?  93  ILE B CA  1 
ATOM   2420 C C   . ILE B 2 90  ? 124.749 131.587 149.963 1.00 50.76  ?  93  ILE B C   1 
ATOM   2421 O O   . ILE B 2 90  ? 125.539 132.485 149.628 1.00 50.76  ?  93  ILE B O   1 
ATOM   2422 C CB  . ILE B 2 90  ? 125.684 130.899 152.198 1.00 50.76  ?  93  ILE B CB  1 
ATOM   2423 C CG1 . ILE B 2 90  ? 126.236 129.734 153.018 1.00 50.76  ?  93  ILE B CG1 1 
ATOM   2424 C CG2 . ILE B 2 90  ? 124.514 131.540 152.910 1.00 50.76  ?  93  ILE B CG2 1 
ATOM   2425 C CD1 . ILE B 2 90  ? 127.739 129.728 153.136 1.00 50.76  ?  93  ILE B CD1 1 
ATOM   2426 N N   . PRO B 2 91  ? 123.468 131.613 149.594 1.00 53.79  ?  94  PRO B N   1 
ATOM   2427 C CA  . PRO B 2 91  ? 122.908 132.802 148.940 1.00 53.79  ?  94  PRO B CA  1 
ATOM   2428 C C   . PRO B 2 91  ? 122.511 133.842 149.979 1.00 53.79  ?  94  PRO B C   1 
ATOM   2429 O O   . PRO B 2 91  ? 121.764 133.552 150.916 1.00 53.79  ?  94  PRO B O   1 
ATOM   2430 C CB  . PRO B 2 91  ? 121.685 132.254 148.198 1.00 53.79  ?  94  PRO B CB  1 
ATOM   2431 C CG  . PRO B 2 91  ? 121.259 131.077 149.013 1.00 53.79  ?  94  PRO B CG  1 
ATOM   2432 C CD  . PRO B 2 91  ? 122.490 130.514 149.685 1.00 53.79  ?  94  PRO B CD  1 
ATOM   2433 N N   . LEU B 2 92  ? 123.019 135.057 149.810 1.00 56.81  ?  95  LEU B N   1 
ATOM   2434 C CA  . LEU B 2 92  ? 122.768 136.132 150.756 1.00 56.81  ?  95  LEU B CA  1 
ATOM   2435 C C   . LEU B 2 92  ? 121.473 136.857 150.416 1.00 56.81  ?  95  LEU B C   1 
ATOM   2436 O O   . LEU B 2 92  ? 121.091 136.976 149.249 1.00 56.81  ?  95  LEU B O   1 
ATOM   2437 C CB  . LEU B 2 92  ? 123.931 137.124 150.765 1.00 56.81  ?  95  LEU B CB  1 
ATOM   2438 C CG  . LEU B 2 92  ? 125.329 136.521 150.903 1.00 56.81  ?  95  LEU B CG  1 
ATOM   2439 C CD1 . LEU B 2 92  ? 126.385 137.609 150.856 1.00 56.81  ?  95  LEU B CD1 1 
ATOM   2440 C CD2 . LEU B 2 92  ? 125.437 135.723 152.188 1.00 56.81  ?  95  LEU B CD2 1 
ATOM   2441 N N   . ARG B 2 93  ? 120.792 137.337 151.460 1.00 67.45  ?  96  ARG B N   1 
ATOM   2442 C CA  . ARG B 2 93  ? 119.584 138.127 151.251 1.00 67.45  ?  96  ARG B CA  1 
ATOM   2443 C C   . ARG B 2 93  ? 119.901 139.427 150.524 1.00 67.45  ?  96  ARG B C   1 
ATOM   2444 O O   . ARG B 2 93  ? 119.153 139.850 149.635 1.00 67.45  ?  96  ARG B O   1 
ATOM   2445 C CB  . ARG B 2 93  ? 118.902 138.411 152.588 1.00 67.45  ?  96  ARG B CB  1 
ATOM   2446 C CG  . ARG B 2 93  ? 117.857 137.381 152.982 1.00 67.45  ?  96  ARG B CG  1 
ATOM   2447 C CD  . ARG B 2 93  ? 117.858 137.138 154.482 1.00 67.45  ?  96  ARG B CD  1 
ATOM   2448 N NE  . ARG B 2 93  ? 117.183 135.895 154.835 1.00 67.45  ?  96  ARG B NE  1 
ATOM   2449 C CZ  . ARG B 2 93  ? 116.820 135.563 156.066 1.00 67.45  ?  96  ARG B CZ  1 
ATOM   2450 N NH1 . ARG B 2 93  ? 117.051 136.363 157.094 1.00 67.45  1  96  ARG B NH1 1 
ATOM   2451 N NH2 . ARG B 2 93  ? 116.209 134.400 156.271 1.00 67.45  ?  96  ARG B NH2 1 
ATOM   2452 N N   . SER B 2 94  ? 121.002 140.074 150.890 1.00 65.55  ?  97  SER B N   1 
ATOM   2453 C CA  . SER B 2 94  ? 121.471 141.284 150.229 1.00 65.55  ?  97  SER B CA  1 
ATOM   2454 C C   . SER B 2 94  ? 122.781 140.984 149.517 1.00 65.55  ?  97  SER B C   1 
ATOM   2455 O O   . SER B 2 94  ? 123.722 140.469 150.130 1.00 65.55  ?  97  SER B O   1 
ATOM   2456 C CB  . SER B 2 94  ? 121.660 142.421 151.234 1.00 65.55  ?  97  SER B CB  1 
ATOM   2457 O OG  . SER B 2 94  ? 121.919 143.647 150.573 1.00 65.55  ?  97  SER B OG  1 
ATOM   2458 N N   . SER B 2 95  ? 122.841 141.307 148.226 1.00 62.31  ?  98  SER B N   1 
ATOM   2459 C CA  . SER B 2 95  ? 124.029 141.030 147.430 1.00 62.31  ?  98  SER B CA  1 
ATOM   2460 C C   . SER B 2 95  ? 125.130 142.063 147.624 1.00 62.31  ?  98  SER B C   1 
ATOM   2461 O O   . SER B 2 95  ? 126.226 141.883 147.083 1.00 62.31  ?  98  SER B O   1 
ATOM   2462 C CB  . SER B 2 95  ? 123.659 140.949 145.947 1.00 62.31  ?  98  SER B CB  1 
ATOM   2463 O OG  . SER B 2 95  ? 123.326 142.226 145.433 1.00 62.31  ?  98  SER B OG  1 
ATOM   2464 N N   . TRP B 2 96  ? 124.871 143.132 148.375 1.00 63.43  ?  99  TRP B N   1 
ATOM   2465 C CA  . TRP B 2 96  ? 125.858 144.190 148.589 1.00 63.43  ?  99  TRP B CA  1 
ATOM   2466 C C   . TRP B 2 96  ? 126.682 143.872 149.837 1.00 63.43  ?  99  TRP B C   1 
ATOM   2467 O O   . TRP B 2 96  ? 126.597 144.530 150.874 1.00 63.43  ?  99  TRP B O   1 
ATOM   2468 C CB  . TRP B 2 96  ? 125.165 145.541 148.696 1.00 63.43  ?  99  TRP B CB  1 
ATOM   2469 C CG  . TRP B 2 96  ? 124.183 145.776 147.597 1.00 63.43  ?  99  TRP B CG  1 
ATOM   2470 C CD1 . TRP B 2 96  ? 122.829 145.868 147.715 1.00 63.43  ?  99  TRP B CD1 1 
ATOM   2471 C CD2 . TRP B 2 96  ? 124.477 145.939 146.206 1.00 63.43  ?  99  TRP B CD2 1 
ATOM   2472 N NE1 . TRP B 2 96  ? 122.260 146.081 146.484 1.00 63.43  ?  99  TRP B NE1 1 
ATOM   2473 C CE2 . TRP B 2 96  ? 123.252 146.128 145.541 1.00 63.43  ?  99  TRP B CE2 1 
ATOM   2474 C CE3 . TRP B 2 96  ? 125.658 145.944 145.459 1.00 63.43  ?  99  TRP B CE3 1 
ATOM   2475 C CZ2 . TRP B 2 96  ? 123.174 146.321 144.166 1.00 63.43  ?  99  TRP B CZ2 1 
ATOM   2476 C CZ3 . TRP B 2 96  ? 125.578 146.134 144.095 1.00 63.43  ?  99  TRP B CZ3 1 
ATOM   2477 C CH2 . TRP B 2 96  ? 124.346 146.321 143.462 1.00 63.43  ?  99  TRP B CH2 1 
ATOM   2478 N N   . VAL B 2 97  ? 127.497 142.830 149.711 1.00 60.18  ?  100 VAL B N   1 
ATOM   2479 C CA  . VAL B 2 97  ? 128.338 142.347 150.800 1.00 60.18  ?  100 VAL B CA  1 
ATOM   2480 C C   . VAL B 2 97  ? 129.744 142.904 150.618 1.00 60.18  ?  100 VAL B C   1 
ATOM   2481 O O   . VAL B 2 97  ? 130.301 142.871 149.513 1.00 60.18  ?  100 VAL B O   1 
ATOM   2482 C CB  . VAL B 2 97  ? 128.340 140.809 150.862 1.00 60.18  ?  100 VAL B CB  1 
ATOM   2483 C CG1 . VAL B 2 97  ? 128.844 140.206 149.562 1.00 60.18  ?  100 VAL B CG1 1 
ATOM   2484 C CG2 . VAL B 2 97  ? 129.173 140.324 152.034 1.00 60.18  ?  100 VAL B CG2 1 
ATOM   2485 N N   . MET B 2 98  ? 130.306 143.448 151.697 1.00 59.76  ?  101 MET B N   1 
ATOM   2486 C CA  . MET B 2 98  ? 131.641 144.025 151.675 1.00 59.76  ?  101 MET B CA  1 
ATOM   2487 C C   . MET B 2 98  ? 132.592 143.380 152.670 1.00 59.76  ?  101 MET B C   1 
ATOM   2488 O O   . MET B 2 98  ? 133.770 143.754 152.705 1.00 59.76  ?  101 MET B O   1 
ATOM   2489 C CB  . MET B 2 98  ? 131.575 145.535 151.944 1.00 59.76  ?  101 MET B CB  1 
ATOM   2490 C CG  . MET B 2 98  ? 130.598 146.283 151.058 1.00 59.76  ?  101 MET B CG  1 
ATOM   2491 S SD  . MET B 2 98  ? 130.339 147.982 151.597 1.00 59.76  ?  101 MET B SD  1 
ATOM   2492 C CE  . MET B 2 98  ? 132.031 148.522 151.815 1.00 59.76  ?  101 MET B CE  1 
ATOM   2493 N N   . THR B 2 99  ? 132.126 142.434 153.482 1.00 56.04  ?  102 THR B N   1 
ATOM   2494 C CA  . THR B 2 99  ? 132.993 141.774 154.445 1.00 56.04  ?  102 THR B CA  1 
ATOM   2495 C C   . THR B 2 99  ? 132.462 140.379 154.737 1.00 56.04  ?  102 THR B C   1 
ATOM   2496 O O   . THR B 2 99  ? 131.281 140.087 154.538 1.00 56.04  ?  102 THR B O   1 
ATOM   2497 C CB  . THR B 2 99  ? 133.108 142.571 155.747 1.00 56.04  ?  102 THR B CB  1 
ATOM   2498 O OG1 . THR B 2 99  ? 134.048 141.931 156.617 1.00 56.04  ?  102 THR B OG1 1 
ATOM   2499 C CG2 . THR B 2 99  ? 131.764 142.646 156.435 1.00 56.04  ?  102 THR B CG2 1 
ATOM   2500 N N   . CYS B 2 100 ? 133.360 139.517 155.208 1.00 51.17  ?  103 CYS B N   1 
ATOM   2501 C CA  . CYS B 2 100 ? 132.978 138.190 155.665 1.00 51.17  ?  103 CYS B CA  1 
ATOM   2502 C C   . CYS B 2 100 ? 134.015 137.707 156.665 1.00 51.17  ?  103 CYS B C   1 
ATOM   2503 O O   . CYS B 2 100 ? 135.196 138.051 156.569 1.00 51.17  ?  103 CYS B O   1 
ATOM   2504 C CB  . CYS B 2 100 ? 132.852 137.192 154.508 1.00 51.17  ?  103 CYS B CB  1 
ATOM   2505 S SG  . CYS B 2 100 ? 134.408 136.737 153.721 1.00 51.17  ?  103 CYS B SG  1 
ATOM   2506 N N   . ALA B 2 101 ? 133.559 136.912 157.628 1.00 50.26  ?  104 ALA B N   1 
ATOM   2507 C CA  . ALA B 2 101 ? 134.431 136.333 158.636 1.00 50.26  ?  104 ALA B CA  1 
ATOM   2508 C C   . ALA B 2 101 ? 134.077 134.867 158.817 1.00 50.26  ?  104 ALA B C   1 
ATOM   2509 O O   . ALA B 2 101 ? 132.946 134.450 158.559 1.00 50.26  ?  104 ALA B O   1 
ATOM   2510 C CB  . ALA B 2 101 ? 134.320 137.066 159.977 1.00 50.26  ?  104 ALA B CB  1 
ATOM   2511 N N   . TYR B 2 102 ? 135.057 134.088 159.262 1.00 53.52  ?  105 TYR B N   1 
ATOM   2512 C CA  . TYR B 2 102 ? 134.879 132.664 159.498 1.00 53.52  ?  105 TYR B CA  1 
ATOM   2513 C C   . TYR B 2 102 ? 135.210 132.395 160.959 1.00 53.52  ?  105 TYR B C   1 
ATOM   2514 O O   . TYR B 2 102 ? 136.286 132.775 161.431 1.00 53.52  ?  105 TYR B O   1 
ATOM   2515 C CB  . TYR B 2 102 ? 135.780 131.844 158.572 1.00 53.52  ?  105 TYR B CB  1 
ATOM   2516 C CG  . TYR B 2 102 ? 135.628 130.347 158.698 1.00 53.52  ?  105 TYR B CG  1 
ATOM   2517 C CD1 . TYR B 2 102 ? 134.534 129.700 158.145 1.00 53.52  ?  105 TYR B CD1 1 
ATOM   2518 C CD2 . TYR B 2 102 ? 136.567 129.583 159.370 1.00 53.52  ?  105 TYR B CD2 1 
ATOM   2519 C CE1 . TYR B 2 102 ? 134.383 128.335 158.245 1.00 53.52  ?  105 TYR B CE1 1 
ATOM   2520 C CE2 . TYR B 2 102 ? 136.424 128.212 159.478 1.00 53.52  ?  105 TYR B CE2 1 
ATOM   2521 C CZ  . TYR B 2 102 ? 135.328 127.595 158.913 1.00 53.52  ?  105 TYR B CZ  1 
ATOM   2522 O OH  . TYR B 2 102 ? 135.174 126.232 159.017 1.00 53.52  ?  105 TYR B OH  1 
ATOM   2523 N N   . ALA B 2 103 ? 134.286 131.756 161.671 1.00 52.16  ?  106 ALA B N   1 
ATOM   2524 C CA  . ALA B 2 103 ? 134.451 131.572 163.104 1.00 52.16  ?  106 ALA B CA  1 
ATOM   2525 C C   . ALA B 2 103 ? 135.659 130.684 163.401 1.00 52.16  ?  106 ALA B C   1 
ATOM   2526 O O   . ALA B 2 103 ? 135.962 129.760 162.642 1.00 52.16  ?  106 ALA B O   1 
ATOM   2527 C CB  . ALA B 2 103 ? 133.196 130.958 163.714 1.00 52.16  ?  106 ALA B CB  1 
ATOM   2528 N N   . PRO B 2 104 ? 136.375 130.957 164.497 1.00 54.91  ?  107 PRO B N   1 
ATOM   2529 C CA  . PRO B 2 104 ? 137.530 130.110 164.838 1.00 54.91  ?  107 PRO B CA  1 
ATOM   2530 C C   . PRO B 2 104 ? 137.164 128.654 165.050 1.00 54.91  ?  107 PRO B C   1 
ATOM   2531 O O   . PRO B 2 104 ? 137.948 127.763 164.702 1.00 54.91  ?  107 PRO B O   1 
ATOM   2532 C CB  . PRO B 2 104 ? 138.068 130.757 166.123 1.00 54.91  ?  107 PRO B CB  1 
ATOM   2533 C CG  . PRO B 2 104 ? 137.543 132.153 166.098 1.00 54.91  ?  107 PRO B CG  1 
ATOM   2534 C CD  . PRO B 2 104 ? 136.200 132.061 165.452 1.00 54.91  ?  107 PRO B CD  1 
ATOM   2535 N N   . SER B 2 105 ? 135.985 128.384 165.614 1.00 57.80  ?  108 SER B N   1 
ATOM   2536 C CA  . SER B 2 105 ? 135.531 127.009 165.765 1.00 57.80  ?  108 SER B CA  1 
ATOM   2537 C C   . SER B 2 105 ? 135.143 126.383 164.434 1.00 57.80  ?  108 SER B C   1 
ATOM   2538 O O   . SER B 2 105 ? 135.135 125.153 164.320 1.00 57.80  ?  108 SER B O   1 
ATOM   2539 C CB  . SER B 2 105 ? 134.347 126.949 166.730 1.00 57.80  ?  108 SER B CB  1 
ATOM   2540 O OG  . SER B 2 105 ? 133.187 127.508 166.142 1.00 57.80  ?  108 SER B OG  1 
ATOM   2541 N N   . GLY B 2 106 ? 134.826 127.197 163.430 1.00 55.00  ?  109 GLY B N   1 
ATOM   2542 C CA  . GLY B 2 106 ? 134.412 126.700 162.138 1.00 55.00  ?  109 GLY B CA  1 
ATOM   2543 C C   . GLY B 2 106 ? 132.936 126.401 162.007 1.00 55.00  ?  109 GLY B C   1 
ATOM   2544 O O   . GLY B 2 106 ? 132.507 125.946 160.940 1.00 55.00  ?  109 GLY B O   1 
ATOM   2545 N N   . ASN B 2 107 ? 132.145 126.641 163.053 1.00 57.27  ?  110 ASN B N   1 
ATOM   2546 C CA  . ASN B 2 107 ? 130.722 126.334 163.009 1.00 57.27  ?  110 ASN B CA  1 
ATOM   2547 C C   . ASN B 2 107 ? 129.892 127.444 162.382 1.00 57.27  ?  110 ASN B C   1 
ATOM   2548 O O   . ASN B 2 107 ? 128.789 127.171 161.898 1.00 57.27  ?  110 ASN B O   1 
ATOM   2549 C CB  . ASN B 2 107 ? 130.202 126.049 164.419 1.00 57.27  ?  110 ASN B CB  1 
ATOM   2550 C CG  . ASN B 2 107 ? 131.056 125.045 165.164 1.00 57.27  ?  110 ASN B CG  1 
ATOM   2551 O OD1 . ASN B 2 107 ? 131.567 124.092 164.577 1.00 57.27  ?  110 ASN B OD1 1 
ATOM   2552 N ND2 . ASN B 2 107 ? 131.213 125.252 166.465 1.00 57.27  ?  110 ASN B ND2 1 
ATOM   2553 N N   . TYR B 2 108 ? 130.387 128.679 162.376 1.00 55.73  ?  111 TYR B N   1 
ATOM   2554 C CA  . TYR B 2 108 ? 129.620 129.818 161.898 1.00 55.73  ?  111 TYR B CA  1 
ATOM   2555 C C   . TYR B 2 108 ? 130.441 130.627 160.906 1.00 55.73  ?  111 TYR B C   1 
ATOM   2556 O O   . TYR B 2 108 ? 131.674 130.593 160.908 1.00 55.73  ?  111 TYR B O   1 
ATOM   2557 C CB  . TYR B 2 108 ? 129.177 130.727 163.053 1.00 55.73  ?  111 TYR B CB  1 
ATOM   2558 C CG  . TYR B 2 108 ? 128.337 130.037 164.100 1.00 55.73  ?  111 TYR B CG  1 
ATOM   2559 C CD1 . TYR B 2 108 ? 126.957 129.976 163.979 1.00 55.73  ?  111 TYR B CD1 1 
ATOM   2560 C CD2 . TYR B 2 108 ? 128.923 129.453 165.212 1.00 55.73  ?  111 TYR B CD2 1 
ATOM   2561 C CE1 . TYR B 2 108 ? 126.185 129.348 164.934 1.00 55.73  ?  111 TYR B CE1 1 
ATOM   2562 C CE2 . TYR B 2 108 ? 128.160 128.822 166.172 1.00 55.73  ?  111 TYR B CE2 1 
ATOM   2563 C CZ  . TYR B 2 108 ? 126.792 128.773 166.029 1.00 55.73  ?  111 TYR B CZ  1 
ATOM   2564 O OH  . TYR B 2 108 ? 126.028 128.145 166.984 1.00 55.73  ?  111 TYR B OH  1 
ATOM   2565 N N   . VAL B 2 109 ? 129.731 131.358 160.048 1.00 52.02  ?  112 VAL B N   1 
ATOM   2566 C CA  . VAL B 2 109 ? 130.333 132.367 159.188 1.00 52.02  ?  112 VAL B CA  1 
ATOM   2567 C C   . VAL B 2 109 ? 129.556 133.662 159.373 1.00 52.02  ?  112 VAL B C   1 
ATOM   2568 O O   . VAL B 2 109 ? 128.431 133.671 159.872 1.00 52.02  ?  112 VAL B O   1 
ATOM   2569 C CB  . VAL B 2 109 ? 130.357 131.961 157.699 1.00 52.02  ?  112 VAL B CB  1 
ATOM   2570 C CG1 . VAL B 2 109 ? 131.297 130.796 157.482 1.00 52.02  ?  112 VAL B CG1 1 
ATOM   2571 C CG2 . VAL B 2 109 ? 128.964 131.621 157.216 1.00 52.02  ?  112 VAL B CG2 1 
ATOM   2572 N N   . ALA B 2 110 ? 130.176 134.766 158.973 1.00 52.33  ?  113 ALA B N   1 
ATOM   2573 C CA  . ALA B 2 110 ? 129.558 136.077 159.088 1.00 52.33  ?  113 ALA B CA  1 
ATOM   2574 C C   . ALA B 2 110 ? 129.672 136.817 157.766 1.00 52.33  ?  113 ALA B C   1 
ATOM   2575 O O   . ALA B 2 110 ? 130.610 136.605 156.996 1.00 52.33  ?  113 ALA B O   1 
ATOM   2576 C CB  . ALA B 2 110 ? 130.200 136.912 160.202 1.00 52.33  ?  113 ALA B CB  1 
ATOM   2577 N N   . CYS B 2 111 ? 128.693 137.678 157.505 1.00 57.75  ?  114 CYS B N   1 
ATOM   2578 C CA  . CYS B 2 111 ? 128.737 138.543 156.336 1.00 57.75  ?  114 CYS B CA  1 
ATOM   2579 C C   . CYS B 2 111 ? 128.021 139.843 156.669 1.00 57.75  ?  114 CYS B C   1 
ATOM   2580 O O   . CYS B 2 111 ? 127.289 139.939 157.655 1.00 57.75  ?  114 CYS B O   1 
ATOM   2581 C CB  . CYS B 2 111 ? 128.111 137.876 155.108 1.00 57.75  ?  114 CYS B CB  1 
ATOM   2582 S SG  . CYS B 2 111 ? 126.309 137.849 155.113 1.00 57.75  ?  114 CYS B SG  1 
ATOM   2583 N N   . GLY B 2 112 ? 128.251 140.850 155.840 1.00 58.33  ?  115 GLY B N   1 
ATOM   2584 C CA  . GLY B 2 112 ? 127.604 142.135 156.028 1.00 58.33  ?  115 GLY B CA  1 
ATOM   2585 C C   . GLY B 2 112 ? 128.022 143.075 154.923 1.00 58.33  ?  115 GLY B C   1 
ATOM   2586 O O   . GLY B 2 112 ? 128.909 142.774 154.120 1.00 58.33  ?  115 GLY B O   1 
ATOM   2587 N N   . GLY B 2 113 ? 127.369 144.231 154.894 1.00 59.86  ?  116 GLY B N   1 
ATOM   2588 C CA  . GLY B 2 113 ? 127.674 145.205 153.867 1.00 59.86  ?  116 GLY B CA  1 
ATOM   2589 C C   . GLY B 2 113 ? 126.782 146.426 153.880 1.00 59.86  ?  116 GLY B C   1 
ATOM   2590 O O   . GLY B 2 113 ? 126.542 147.021 154.933 1.00 59.86  ?  116 GLY B O   1 
ATOM   2591 N N   . LEU B 2 114 ? 126.282 146.805 152.704 1.00 63.84  ?  117 LEU B N   1 
ATOM   2592 C CA  . LEU B 2 114 ? 125.487 148.018 152.567 1.00 63.84  ?  117 LEU B CA  1 
ATOM   2593 C C   . LEU B 2 114 ? 124.107 147.904 153.200 1.00 63.84  ?  117 LEU B C   1 
ATOM   2594 O O   . LEU B 2 114 ? 123.411 148.919 153.303 1.00 63.84  ?  117 LEU B O   1 
ATOM   2595 C CB  . LEU B 2 114 ? 125.350 148.383 151.089 1.00 63.84  ?  117 LEU B CB  1 
ATOM   2596 C CG  . LEU B 2 114 ? 126.602 148.929 150.405 1.00 63.84  ?  117 LEU B CG  1 
ATOM   2597 C CD1 . LEU B 2 114 ? 126.409 148.990 148.901 1.00 63.84  ?  117 LEU B CD1 1 
ATOM   2598 C CD2 . LEU B 2 114 ? 126.945 150.298 150.954 1.00 63.84  ?  117 LEU B CD2 1 
ATOM   2599 N N   . ASP B 2 115 ? 123.696 146.712 153.624 1.00 65.58  ?  118 ASP B N   1 
ATOM   2600 C CA  . ASP B 2 115 ? 122.405 146.537 154.277 1.00 65.58  ?  118 ASP B CA  1 
ATOM   2601 C C   . ASP B 2 115 ? 122.444 146.871 155.762 1.00 65.58  ?  118 ASP B C   1 
ATOM   2602 O O   . ASP B 2 115 ? 121.404 146.784 156.424 1.00 65.58  ?  118 ASP B O   1 
ATOM   2603 C CB  . ASP B 2 115 ? 121.907 145.103 154.084 1.00 65.58  ?  118 ASP B CB  1 
ATOM   2604 C CG  . ASP B 2 115 ? 122.940 144.069 154.483 1.00 65.58  ?  118 ASP B CG  1 
ATOM   2605 O OD1 . ASP B 2 115 ? 124.098 144.454 154.742 1.00 65.58  ?  118 ASP B OD1 1 
ATOM   2606 O OD2 . ASP B 2 115 ? 122.593 142.871 154.540 1.00 65.58  -1 118 ASP B OD2 1 
ATOM   2607 N N   . ASN B 2 116 ? 123.612 147.232 156.296 1.00 63.68  ?  119 ASN B N   1 
ATOM   2608 C CA  . ASN B 2 116 ? 123.799 147.647 157.683 1.00 63.68  ?  119 ASN B CA  1 
ATOM   2609 C C   . ASN B 2 116 ? 123.477 146.540 158.678 1.00 63.68  ?  119 ASN B C   1 
ATOM   2610 O O   . ASN B 2 116 ? 123.220 146.819 159.853 1.00 63.68  ?  119 ASN B O   1 
ATOM   2611 C CB  . ASN B 2 116 ? 122.966 148.891 158.013 1.00 63.68  ?  119 ASN B CB  1 
ATOM   2612 C CG  . ASN B 2 116 ? 123.151 150.000 157.002 1.00 63.68  ?  119 ASN B CG  1 
ATOM   2613 O OD1 . ASN B 2 116 ? 124.187 150.093 156.349 1.00 63.68  ?  119 ASN B OD1 1 
ATOM   2614 N ND2 . ASN B 2 116 ? 122.147 150.857 156.874 1.00 63.68  ?  119 ASN B ND2 1 
ATOM   2615 N N   . ILE B 2 117 ? 123.487 145.285 158.238 1.00 62.16  ?  120 ILE B N   1 
ATOM   2616 C CA  . ILE B 2 117 ? 123.124 144.149 159.074 1.00 62.16  ?  120 ILE B CA  1 
ATOM   2617 C C   . ILE B 2 117 ? 124.218 143.098 158.971 1.00 62.16  ?  120 ILE B C   1 
ATOM   2618 O O   . ILE B 2 117 ? 124.682 142.779 157.871 1.00 62.16  ?  120 ILE B O   1 
ATOM   2619 C CB  . ILE B 2 117 ? 121.758 143.558 158.663 1.00 62.16  ?  120 ILE B CB  1 
ATOM   2620 C CG1 . ILE B 2 117 ? 120.632 144.536 158.999 1.00 62.16  ?  120 ILE B CG1 1 
ATOM   2621 C CG2 . ILE B 2 117 ? 121.519 142.223 159.343 1.00 62.16  ?  120 ILE B CG2 1 
ATOM   2622 C CD1 . ILE B 2 117 ? 119.299 144.155 158.402 1.00 62.16  ?  120 ILE B CD1 1 
ATOM   2623 N N   . CYS B 2 118 ? 124.633 142.563 160.117 1.00 61.27  ?  121 CYS B N   1 
ATOM   2624 C CA  . CYS B 2 118 ? 125.624 141.494 160.170 1.00 61.27  ?  121 CYS B CA  1 
ATOM   2625 C C   . CYS B 2 118 ? 124.886 140.166 160.286 1.00 61.27  ?  121 CYS B C   1 
ATOM   2626 O O   . CYS B 2 118 ? 124.247 139.891 161.305 1.00 61.27  ?  121 CYS B O   1 
ATOM   2627 C CB  . CYS B 2 118 ? 126.584 141.692 161.340 1.00 61.27  ?  121 CYS B CB  1 
ATOM   2628 S SG  . CYS B 2 118 ? 128.016 140.591 161.318 1.00 61.27  ?  121 CYS B SG  1 
ATOM   2629 N N   . SER B 2 119 ? 124.971 139.347 159.246 1.00 58.86  ?  122 SER B N   1 
ATOM   2630 C CA  . SER B 2 119 ? 124.295 138.060 159.210 1.00 58.86  ?  122 SER B CA  1 
ATOM   2631 C C   . SER B 2 119 ? 125.268 136.962 159.616 1.00 58.86  ?  122 SER B C   1 
ATOM   2632 O O   . SER B 2 119 ? 126.343 136.827 159.022 1.00 58.86  ?  122 SER B O   1 
ATOM   2633 C CB  . SER B 2 119 ? 123.730 137.782 157.818 1.00 58.86  ?  122 SER B CB  1 
ATOM   2634 O OG  . SER B 2 119 ? 122.844 138.811 157.415 1.00 58.86  ?  122 SER B OG  1 
ATOM   2635 N N   . ILE B 2 120 ? 124.886 136.189 160.628 1.00 56.94  ?  123 ILE B N   1 
ATOM   2636 C CA  . ILE B 2 120 ? 125.658 135.051 161.107 1.00 56.94  ?  123 ILE B CA  1 
ATOM   2637 C C   . ILE B 2 120 ? 124.950 133.787 160.644 1.00 56.94  ?  123 ILE B C   1 
ATOM   2638 O O   . ILE B 2 120 ? 123.788 133.554 161.001 1.00 56.94  ?  123 ILE B O   1 
ATOM   2639 C CB  . ILE B 2 120 ? 125.799 135.072 162.637 1.00 56.94  ?  123 ILE B CB  1 
ATOM   2640 C CG1 . ILE B 2 120 ? 126.129 136.482 163.128 1.00 56.94  ?  123 ILE B CG1 1 
ATOM   2641 C CG2 . ILE B 2 120 ? 126.857 134.081 163.088 1.00 56.94  ?  123 ILE B CG2 1 
ATOM   2642 C CD1 . ILE B 2 120 ? 127.510 136.949 162.754 1.00 56.94  ?  123 ILE B CD1 1 
ATOM   2643 N N   . TYR B 2 121 ? 125.653 132.976 159.859 1.00 55.39  ?  124 TYR B N   1 
ATOM   2644 C CA  . TYR B 2 121 ? 125.124 131.752 159.280 1.00 55.39  ?  124 TYR B CA  1 
ATOM   2645 C C   . TYR B 2 121 ? 125.719 130.549 159.995 1.00 55.39  ?  124 TYR B C   1 
ATOM   2646 O O   . TYR B 2 121 ? 126.929 130.498 160.242 1.00 55.39  ?  124 TYR B O   1 
ATOM   2647 C CB  . TYR B 2 121 ? 125.447 131.661 157.787 1.00 55.39  ?  124 TYR B CB  1 
ATOM   2648 C CG  . TYR B 2 121 ? 124.787 132.717 156.935 1.00 55.39  ?  124 TYR B CG  1 
ATOM   2649 C CD1 . TYR B 2 121 ? 125.341 133.982 156.818 1.00 55.39  ?  124 TYR B CD1 1 
ATOM   2650 C CD2 . TYR B 2 121 ? 123.626 132.443 156.230 1.00 55.39  ?  124 TYR B CD2 1 
ATOM   2651 C CE1 . TYR B 2 121 ? 124.749 134.949 156.037 1.00 55.39  ?  124 TYR B CE1 1 
ATOM   2652 C CE2 . TYR B 2 121 ? 123.026 133.406 155.445 1.00 55.39  ?  124 TYR B CE2 1 
ATOM   2653 C CZ  . TYR B 2 121 ? 123.592 134.657 155.352 1.00 55.39  ?  124 TYR B CZ  1 
ATOM   2654 O OH  . TYR B 2 121 ? 122.998 135.620 154.570 1.00 55.39  ?  124 TYR B OH  1 
ATOM   2655 N N   . ASN B 2 122 ? 124.864 129.580 160.312 1.00 57.61  ?  125 ASN B N   1 
ATOM   2656 C CA  . ASN B 2 122 ? 125.276 128.358 160.989 1.00 57.61  ?  125 ASN B CA  1 
ATOM   2657 C C   . ASN B 2 122 ? 125.596 127.283 159.958 1.00 57.61  ?  125 ASN B C   1 
ATOM   2658 O O   . ASN B 2 122 ? 124.774 126.986 159.086 1.00 57.61  ?  125 ASN B O   1 
ATOM   2659 C CB  . ASN B 2 122 ? 124.175 127.876 161.934 1.00 57.61  ?  125 ASN B CB  1 
ATOM   2660 C CG  . ASN B 2 122 ? 124.642 126.774 162.861 1.00 57.61  ?  125 ASN B CG  1 
ATOM   2661 O OD1 . ASN B 2 122 ? 125.804 126.371 162.833 1.00 57.61  ?  125 ASN B OD1 1 
ATOM   2662 N ND2 . ASN B 2 122 ? 123.733 126.279 163.692 1.00 57.61  ?  125 ASN B ND2 1 
ATOM   2663 N N   . LEU B 2 123 ? 126.789 126.701 160.063 1.00 53.21  ?  126 LEU B N   1 
ATOM   2664 C CA  . LEU B 2 123 ? 127.239 125.689 159.115 1.00 53.21  ?  126 LEU B CA  1 
ATOM   2665 C C   . LEU B 2 123 ? 126.972 124.264 159.575 1.00 53.21  ?  126 LEU B C   1 
ATOM   2666 O O   . LEU B 2 123 ? 126.743 123.389 158.735 1.00 53.21  ?  126 LEU B O   1 
ATOM   2667 C CB  . LEU B 2 123 ? 128.738 125.845 158.843 1.00 53.21  ?  126 LEU B CB  1 
ATOM   2668 C CG  . LEU B 2 123 ? 129.209 127.227 158.399 1.00 53.21  ?  126 LEU B CG  1 
ATOM   2669 C CD1 . LEU B 2 123 ? 130.698 127.208 158.107 1.00 53.21  ?  126 LEU B CD1 1 
ATOM   2670 C CD2 . LEU B 2 123 ? 128.424 127.691 157.188 1.00 53.21  ?  126 LEU B CD2 1 
ATOM   2671 N N   . LYS B 2 124 ? 126.996 124.008 160.880 1.00 57.60  ?  127 LYS B N   1 
ATOM   2672 C CA  . LYS B 2 124 ? 126.806 122.665 161.425 1.00 57.60  ?  127 LYS B CA  1 
ATOM   2673 C C   . LYS B 2 124 ? 125.370 122.555 161.925 1.00 57.60  ?  127 LYS B C   1 
ATOM   2674 O O   . LYS B 2 124 ? 125.082 122.770 163.102 1.00 57.60  ?  127 LYS B O   1 
ATOM   2675 C CB  . LYS B 2 124 ? 127.813 122.381 162.532 1.00 57.60  ?  127 LYS B CB  1 
ATOM   2676 C CG  . LYS B 2 124 ? 129.216 122.880 162.235 1.00 57.60  ?  127 LYS B CG  1 
ATOM   2677 C CD  . LYS B 2 124 ? 129.891 122.032 161.171 1.00 57.60  ?  127 LYS B CD  1 
ATOM   2678 C CE  . LYS B 2 124 ? 131.352 122.411 161.013 1.00 57.60  ?  127 LYS B CE  1 
ATOM   2679 N NZ  . LYS B 2 124 ? 132.132 122.140 162.251 1.00 57.60  1  127 LYS B NZ  1 
ATOM   2680 N N   . THR B 2 125 ? 124.462 122.213 161.016 1.00 65.45  ?  128 THR B N   1 
ATOM   2681 C CA  . THR B 2 125 ? 123.052 122.051 161.332 1.00 65.45  ?  128 THR B CA  1 
ATOM   2682 C C   . THR B 2 125 ? 122.616 120.624 161.033 1.00 65.45  ?  128 THR B C   1 
ATOM   2683 O O   . THR B 2 125 ? 123.120 119.985 160.105 1.00 65.45  ?  128 THR B O   1 
ATOM   2684 C CB  . THR B 2 125 ? 122.181 123.034 160.537 1.00 65.45  ?  128 THR B CB  1 
ATOM   2685 O OG1 . THR B 2 125 ? 122.268 122.731 159.140 1.00 65.45  ?  128 THR B OG1 1 
ATOM   2686 C CG2 . THR B 2 125 ? 122.641 124.462 160.768 1.00 65.45  ?  128 THR B CG2 1 
ATOM   2687 N N   . ARG B 2 126 ? 121.674 120.127 161.837 1.00 70.89  ?  129 ARG B N   1 
ATOM   2688 C CA  . ARG B 2 126 ? 121.151 118.782 161.621 1.00 70.89  ?  129 ARG B CA  1 
ATOM   2689 C C   . ARG B 2 126 ? 120.393 118.678 160.304 1.00 70.89  ?  129 ARG B C   1 
ATOM   2690 O O   . ARG B 2 126 ? 120.320 117.592 159.718 1.00 70.89  ?  129 ARG B O   1 
ATOM   2691 C CB  . ARG B 2 126 ? 120.249 118.375 162.784 1.00 70.89  ?  129 ARG B CB  1 
ATOM   2692 C CG  . ARG B 2 126 ? 120.993 117.772 163.962 1.00 70.89  ?  129 ARG B CG  1 
ATOM   2693 C CD  . ARG B 2 126 ? 121.145 116.269 163.804 1.00 70.89  ?  129 ARG B CD  1 
ATOM   2694 N NE  . ARG B 2 126 ? 120.014 115.544 164.369 1.00 70.89  ?  129 ARG B NE  1 
ATOM   2695 C CZ  . ARG B 2 126 ? 119.915 114.222 164.407 1.00 70.89  ?  129 ARG B CZ  1 
ATOM   2696 N NH1 . ARG B 2 126 ? 120.866 113.444 163.917 1.00 70.89  1  129 ARG B NH1 1 
ATOM   2697 N NH2 . ARG B 2 126 ? 118.835 113.668 164.951 1.00 70.89  ?  129 ARG B NH2 1 
ATOM   2698 N N   . GLU B 2 127 ? 119.827 119.786 159.825 1.00 70.20  ?  130 GLU B N   1 
ATOM   2699 C CA  . GLU B 2 127 ? 119.100 119.787 158.563 1.00 70.20  ?  130 GLU B CA  1 
ATOM   2700 C C   . GLU B 2 127 ? 120.007 119.582 157.358 1.00 70.20  ?  130 GLU B C   1 
ATOM   2701 O O   . GLU B 2 127 ? 119.503 119.285 156.271 1.00 70.20  ?  130 GLU B O   1 
ATOM   2702 C CB  . GLU B 2 127 ? 118.326 121.097 158.405 1.00 70.20  ?  130 GLU B CB  1 
ATOM   2703 C CG  . GLU B 2 127 ? 116.991 121.126 159.129 1.00 70.20  ?  130 GLU B CG  1 
ATOM   2704 C CD  . GLU B 2 127 ? 117.144 121.184 160.635 1.00 70.20  ?  130 GLU B CD  1 
ATOM   2705 O OE1 . GLU B 2 127 ? 117.917 122.035 161.123 1.00 70.20  ?  130 GLU B OE1 1 
ATOM   2706 O OE2 . GLU B 2 127 ? 116.490 120.380 161.332 1.00 70.20  -1 130 GLU B OE2 1 
ATOM   2707 N N   . GLY B 2 128 ? 121.319 119.735 157.520 1.00 66.97  ?  131 GLY B N   1 
ATOM   2708 C CA  . GLY B 2 128 ? 122.253 119.549 156.432 1.00 66.97  ?  131 GLY B CA  1 
ATOM   2709 C C   . GLY B 2 128 ? 122.444 120.744 155.528 1.00 66.97  ?  131 GLY B C   1 
ATOM   2710 O O   . GLY B 2 128 ? 123.222 120.655 154.570 1.00 66.97  ?  131 GLY B O   1 
ATOM   2711 N N   . ASN B 2 129 ? 121.765 121.855 155.792 1.00 67.24  ?  132 ASN B N   1 
ATOM   2712 C CA  . ASN B 2 129 ? 121.913 123.075 155.016 1.00 67.24  ?  132 ASN B CA  1 
ATOM   2713 C C   . ASN B 2 129 ? 122.453 124.187 155.906 1.00 67.24  ?  132 ASN B C   1 
ATOM   2714 O O   . ASN B 2 129 ? 122.589 124.034 157.122 1.00 67.24  ?  132 ASN B O   1 
ATOM   2715 C CB  . ASN B 2 129 ? 120.580 123.495 154.382 1.00 67.24  ?  132 ASN B CB  1 
ATOM   2716 C CG  . ASN B 2 129 ? 119.439 123.534 155.383 1.00 67.24  ?  132 ASN B CG  1 
ATOM   2717 O OD1 . ASN B 2 129 ? 119.655 123.503 156.594 1.00 67.24  ?  132 ASN B OD1 1 
ATOM   2718 N ND2 . ASN B 2 129 ? 118.214 123.605 154.878 1.00 67.24  ?  132 ASN B ND2 1 
ATOM   2719 N N   . VAL B 2 130 ? 122.762 125.318 155.282 1.00 60.47  ?  133 VAL B N   1 
ATOM   2720 C CA  . VAL B 2 130 ? 123.238 126.501 155.987 1.00 60.47  ?  133 VAL B CA  1 
ATOM   2721 C C   . VAL B 2 130 ? 122.071 127.468 156.121 1.00 60.47  ?  133 VAL B C   1 
ATOM   2722 O O   . VAL B 2 130 ? 121.438 127.833 155.123 1.00 60.47  ?  133 VAL B O   1 
ATOM   2723 C CB  . VAL B 2 130 ? 124.419 127.156 155.255 1.00 60.47  ?  133 VAL B CB  1 
ATOM   2724 C CG1 . VAL B 2 130 ? 124.943 128.331 156.058 1.00 60.47  ?  133 VAL B CG1 1 
ATOM   2725 C CG2 . VAL B 2 130 ? 125.518 126.139 155.012 1.00 60.47  ?  133 VAL B CG2 1 
ATOM   2726 N N   . ARG B 2 131 ? 121.784 127.882 157.351 1.00 64.76  ?  134 ARG B N   1 
ATOM   2727 C CA  . ARG B 2 131 ? 120.666 128.765 157.636 1.00 64.76  ?  134 ARG B CA  1 
ATOM   2728 C C   . ARG B 2 131 ? 121.154 129.968 158.429 1.00 64.76  ?  134 ARG B C   1 
ATOM   2729 O O   . ARG B 2 131 ? 122.177 129.907 159.115 1.00 64.76  ?  134 ARG B O   1 
ATOM   2730 C CB  . ARG B 2 131 ? 119.560 128.036 158.410 1.00 64.76  ?  134 ARG B CB  1 
ATOM   2731 C CG  . ARG B 2 131 ? 119.967 127.588 159.800 1.00 64.76  ?  134 ARG B CG  1 
ATOM   2732 C CD  . ARG B 2 131 ? 118.846 126.822 160.478 1.00 64.76  ?  134 ARG B CD  1 
ATOM   2733 N NE  . ARG B 2 131 ? 119.216 126.386 161.818 1.00 64.76  ?  134 ARG B NE  1 
ATOM   2734 C CZ  . ARG B 2 131 ? 118.417 125.712 162.634 1.00 64.76  ?  134 ARG B CZ  1 
ATOM   2735 N NH1 . ARG B 2 131 ? 117.188 125.377 162.276 1.00 64.76  1  134 ARG B NH1 1 
ATOM   2736 N NH2 . ARG B 2 131 ? 118.861 125.364 163.838 1.00 64.76  ?  134 ARG B NH2 1 
ATOM   2737 N N   . VAL B 2 132 ? 120.410 131.067 158.322 1.00 62.59  ?  135 VAL B N   1 
ATOM   2738 C CA  . VAL B 2 132 ? 120.771 132.302 159.010 1.00 62.59  ?  135 VAL B CA  1 
ATOM   2739 C C   . VAL B 2 132 ? 120.579 132.082 160.507 1.00 62.59  ?  135 VAL B C   1 
ATOM   2740 O O   . VAL B 2 132 ? 119.447 132.030 160.996 1.00 62.59  ?  135 VAL B O   1 
ATOM   2741 C CB  . VAL B 2 132 ? 119.938 133.487 158.513 1.00 62.59  ?  135 VAL B CB  1 
ATOM   2742 C CG1 . VAL B 2 132 ? 120.461 134.786 159.101 1.00 62.59  ?  135 VAL B CG1 1 
ATOM   2743 C CG2 . VAL B 2 132 ? 119.938 133.540 156.997 1.00 62.59  ?  135 VAL B CG2 1 
ATOM   2744 N N   . SER B 2 133 ? 121.686 131.948 161.238 1.00 61.90  ?  136 SER B N   1 
ATOM   2745 C CA  . SER B 2 133 ? 121.593 131.764 162.681 1.00 61.90  ?  136 SER B CA  1 
ATOM   2746 C C   . SER B 2 133 ? 121.156 133.046 163.374 1.00 61.90  ?  136 SER B C   1 
ATOM   2747 O O   . SER B 2 133 ? 120.391 133.003 164.345 1.00 61.90  ?  136 SER B O   1 
ATOM   2748 C CB  . SER B 2 133 ? 122.932 131.284 163.237 1.00 61.90  ?  136 SER B CB  1 
ATOM   2749 O OG  . SER B 2 133 ? 122.926 131.293 164.653 1.00 61.90  ?  136 SER B OG  1 
ATOM   2750 N N   . ARG B 2 134 ? 121.627 134.194 162.894 1.00 65.30  ?  137 ARG B N   1 
ATOM   2751 C CA  . ARG B 2 134 ? 121.313 135.458 163.548 1.00 65.30  ?  137 ARG B CA  1 
ATOM   2752 C C   . ARG B 2 134 ? 121.454 136.592 162.543 1.00 65.30  ?  137 ARG B C   1 
ATOM   2753 O O   . ARG B 2 134 ? 122.185 136.484 161.557 1.00 65.30  ?  137 ARG B O   1 
ATOM   2754 C CB  . ARG B 2 134 ? 122.219 135.688 164.764 1.00 65.30  ?  137 ARG B CB  1 
ATOM   2755 C CG  . ARG B 2 134 ? 121.807 136.843 165.660 1.00 65.30  ?  137 ARG B CG  1 
ATOM   2756 C CD  . ARG B 2 134 ? 120.442 136.608 166.276 1.00 65.30  ?  137 ARG B CD  1 
ATOM   2757 N NE  . ARG B 2 134 ? 120.381 135.346 167.002 1.00 65.30  ?  137 ARG B NE  1 
ATOM   2758 C CZ  . ARG B 2 134 ? 119.355 134.960 167.746 1.00 65.30  ?  137 ARG B CZ  1 
ATOM   2759 N NH1 . ARG B 2 134 ? 118.282 135.721 167.891 1.00 65.30  1  137 ARG B NH1 1 
ATOM   2760 N NH2 . ARG B 2 134 ? 119.406 133.782 168.361 1.00 65.30  ?  137 ARG B NH2 1 
ATOM   2761 N N   . GLU B 2 135 ? 120.744 137.686 162.810 1.00 67.32  ?  138 GLU B N   1 
ATOM   2762 C CA  . GLU B 2 135 ? 120.823 138.901 162.000 1.00 67.32  ?  138 GLU B CA  1 
ATOM   2763 C C   . GLU B 2 135 ? 120.963 140.089 162.946 1.00 67.32  ?  138 GLU B C   1 
ATOM   2764 O O   . GLU B 2 135 ? 119.962 140.647 163.405 1.00 67.32  ?  138 GLU B O   1 
ATOM   2765 C CB  . GLU B 2 135 ? 119.600 139.048 161.102 1.00 67.32  ?  138 GLU B CB  1 
ATOM   2766 C CG  . GLU B 2 135 ? 119.820 138.570 159.678 1.00 67.32  ?  138 GLU B CG  1 
ATOM   2767 C CD  . GLU B 2 135 ? 118.626 138.835 158.785 1.00 67.32  ?  138 GLU B CD  1 
ATOM   2768 O OE1 . GLU B 2 135 ? 117.617 139.376 159.285 1.00 67.32  ?  138 GLU B OE1 1 
ATOM   2769 O OE2 . GLU B 2 135 ? 118.695 138.503 157.583 1.00 67.32  -1 138 GLU B OE2 1 
ATOM   2770 N N   . LEU B 2 136 ? 122.204 140.472 163.237 1.00 63.25  ?  139 LEU B N   1 
ATOM   2771 C CA  . LEU B 2 136 ? 122.478 141.590 164.128 1.00 63.25  ?  139 LEU B CA  1 
ATOM   2772 C C   . LEU B 2 136 ? 122.237 142.901 163.391 1.00 63.25  ?  139 LEU B C   1 
ATOM   2773 O O   . LEU B 2 136 ? 122.821 143.141 162.328 1.00 63.25  ?  139 LEU B O   1 
ATOM   2774 C CB  . LEU B 2 136 ? 123.915 141.517 164.637 1.00 63.25  ?  139 LEU B CB  1 
ATOM   2775 C CG  . LEU B 2 136 ? 124.392 140.144 165.109 1.00 63.25  ?  139 LEU B CG  1 
ATOM   2776 C CD1 . LEU B 2 136 ? 125.906 140.100 165.172 1.00 63.25  ?  139 LEU B CD1 1 
ATOM   2777 C CD2 . LEU B 2 136 ? 123.791 139.809 166.461 1.00 63.25  ?  139 LEU B CD2 1 
ATOM   2778 N N   . ALA B 2 137 ? 121.381 143.748 163.957 1.00 64.31  ?  140 ALA B N   1 
ATOM   2779 C CA  . ALA B 2 137 ? 121.058 145.043 163.384 1.00 64.31  ?  140 ALA B CA  1 
ATOM   2780 C C   . ALA B 2 137 ? 121.250 146.124 164.437 1.00 64.31  ?  140 ALA B C   1 
ATOM   2781 O O   . ALA B 2 137 ? 121.200 145.864 165.642 1.00 64.31  ?  140 ALA B O   1 
ATOM   2782 C CB  . ALA B 2 137 ? 119.623 145.081 162.844 1.00 64.31  ?  140 ALA B CB  1 
ATOM   2783 N N   . GLY B 2 138 ? 121.458 147.351 163.968 1.00 65.76  ?  141 GLY B N   1 
ATOM   2784 C CA  . GLY B 2 138 ? 121.707 148.464 164.861 1.00 65.76  ?  141 GLY B CA  1 
ATOM   2785 C C   . GLY B 2 138 ? 122.711 149.461 164.321 1.00 65.76  ?  141 GLY B C   1 
ATOM   2786 O O   . GLY B 2 138 ? 122.694 150.633 164.705 1.00 65.76  ?  141 GLY B O   1 
ATOM   2787 N N   . HIS B 2 139 ? 123.593 149.011 163.433 1.00 62.51  ?  142 HIS B N   1 
ATOM   2788 C CA  . HIS B 2 139 ? 124.498 149.930 162.760 1.00 62.51  ?  142 HIS B CA  1 
ATOM   2789 C C   . HIS B 2 139 ? 123.723 150.792 161.772 1.00 62.51  ?  142 HIS B C   1 
ATOM   2790 O O   . HIS B 2 139 ? 122.873 150.299 161.027 1.00 62.51  ?  142 HIS B O   1 
ATOM   2791 C CB  . HIS B 2 139 ? 125.602 149.162 162.035 1.00 62.51  ?  142 HIS B CB  1 
ATOM   2792 C CG  . HIS B 2 139 ? 126.746 148.766 162.915 1.00 62.51  ?  142 HIS B CG  1 
ATOM   2793 N ND1 . HIS B 2 139 ? 127.389 149.657 163.746 1.00 62.51  ?  142 HIS B ND1 1 
ATOM   2794 C CD2 . HIS B 2 139 ? 127.368 147.576 163.086 1.00 62.51  ?  142 HIS B CD2 1 
ATOM   2795 C CE1 . HIS B 2 139 ? 128.354 149.031 164.396 1.00 62.51  ?  142 HIS B CE1 1 
ATOM   2796 N NE2 . HIS B 2 139 ? 128.363 147.768 164.013 1.00 62.51  ?  142 HIS B NE2 1 
ATOM   2797 N N   . THR B 2 140 ? 124.018 152.090 161.768 1.00 62.70  ?  143 THR B N   1 
ATOM   2798 C CA  . THR B 2 140 ? 123.356 153.033 160.877 1.00 62.70  ?  143 THR B CA  1 
ATOM   2799 C C   . THR B 2 140 ? 124.156 153.299 159.609 1.00 62.70  ?  143 THR B C   1 
ATOM   2800 O O   . THR B 2 140 ? 123.766 154.155 158.809 1.00 62.70  ?  143 THR B O   1 
ATOM   2801 C CB  . THR B 2 140 ? 123.080 154.349 161.607 1.00 62.70  ?  143 THR B CB  1 
ATOM   2802 O OG1 . THR B 2 140 ? 124.262 155.157 161.608 1.00 62.70  ?  143 THR B OG1 1 
ATOM   2803 C CG2 . THR B 2 140 ? 122.655 154.082 163.041 1.00 62.70  ?  143 THR B CG2 1 
ATOM   2804 N N   . GLY B 2 141 ? 125.263 152.586 159.409 1.00 61.68  ?  144 GLY B N   1 
ATOM   2805 C CA  . GLY B 2 141 ? 126.048 152.732 158.203 1.00 61.68  ?  144 GLY B CA  1 
ATOM   2806 C C   . GLY B 2 141 ? 126.464 151.373 157.680 1.00 61.68  ?  144 GLY B C   1 
ATOM   2807 O O   . GLY B 2 141 ? 126.290 150.348 158.343 1.00 61.68  ?  144 GLY B O   1 
ATOM   2808 N N   . TYR B 2 142 ? 127.006 151.379 156.462 1.00 62.18  ?  145 TYR B N   1 
ATOM   2809 C CA  . TYR B 2 142 ? 127.442 150.140 155.832 1.00 62.18  ?  145 TYR B CA  1 
ATOM   2810 C C   . TYR B 2 142 ? 128.478 149.442 156.701 1.00 62.18  ?  145 TYR B C   1 
ATOM   2811 O O   . TYR B 2 142 ? 129.405 150.070 157.215 1.00 62.18  ?  145 TYR B O   1 
ATOM   2812 C CB  . TYR B 2 142 ? 128.016 150.418 154.440 1.00 62.18  ?  145 TYR B CB  1 
ATOM   2813 C CG  . TYR B 2 142 ? 129.326 151.175 154.441 1.00 62.18  ?  145 TYR B CG  1 
ATOM   2814 C CD1 . TYR B 2 142 ? 129.349 152.560 154.499 1.00 62.18  ?  145 TYR B CD1 1 
ATOM   2815 C CD2 . TYR B 2 142 ? 130.540 150.504 154.374 1.00 62.18  ?  145 TYR B CD2 1 
ATOM   2816 C CE1 . TYR B 2 142 ? 130.541 153.254 154.499 1.00 62.18  ?  145 TYR B CE1 1 
ATOM   2817 C CE2 . TYR B 2 142 ? 131.737 151.191 154.375 1.00 62.18  ?  145 TYR B CE2 1 
ATOM   2818 C CZ  . TYR B 2 142 ? 131.730 152.566 154.436 1.00 62.18  ?  145 TYR B CZ  1 
ATOM   2819 O OH  . TYR B 2 142 ? 132.918 153.259 154.436 1.00 62.18  ?  145 TYR B OH  1 
ATOM   2820 N N   . LEU B 2 143 ? 128.310 148.135 156.870 1.00 58.59  ?  146 LEU B N   1 
ATOM   2821 C CA  . LEU B 2 143 ? 129.178 147.348 157.737 1.00 58.59  ?  146 LEU B CA  1 
ATOM   2822 C C   . LEU B 2 143 ? 130.356 146.854 156.905 1.00 58.59  ?  146 LEU B C   1 
ATOM   2823 O O   . LEU B 2 143 ? 130.184 146.047 155.987 1.00 58.59  ?  146 LEU B O   1 
ATOM   2824 C CB  . LEU B 2 143 ? 128.393 146.201 158.368 1.00 58.59  ?  146 LEU B CB  1 
ATOM   2825 C CG  . LEU B 2 143 ? 129.037 145.386 159.488 1.00 58.59  ?  146 LEU B CG  1 
ATOM   2826 C CD1 . LEU B 2 143 ? 127.965 144.921 160.450 1.00 58.59  ?  146 LEU B CD1 1 
ATOM   2827 C CD2 . LEU B 2 143 ? 129.782 144.192 158.935 1.00 58.59  ?  146 LEU B CD2 1 
ATOM   2828 N N   . SER B 2 144 ? 131.555 147.340 157.229 1.00 55.89  ?  147 SER B N   1 
ATOM   2829 C CA  . SER B 2 144 ? 132.733 147.123 156.401 1.00 55.89  ?  147 SER B CA  1 
ATOM   2830 C C   . SER B 2 144 ? 133.632 145.997 156.888 1.00 55.89  ?  147 SER B C   1 
ATOM   2831 O O   . SER B 2 144 ? 134.430 145.483 156.097 1.00 55.89  ?  147 SER B O   1 
ATOM   2832 C CB  . SER B 2 144 ? 133.558 148.411 156.312 1.00 55.89  ?  147 SER B CB  1 
ATOM   2833 O OG  . SER B 2 144 ? 133.922 148.869 157.601 1.00 55.89  ?  147 SER B OG  1 
ATOM   2834 N N   . CYS B 2 145 ? 133.543 145.610 158.159 1.00 56.76  ?  148 CYS B N   1 
ATOM   2835 C CA  . CYS B 2 145 ? 134.373 144.532 158.671 1.00 56.76  ?  148 CYS B CA  1 
ATOM   2836 C C   . CYS B 2 145 ? 133.662 143.848 159.828 1.00 56.76  ?  148 CYS B C   1 
ATOM   2837 O O   . CYS B 2 145 ? 132.816 144.439 160.503 1.00 56.76  ?  148 CYS B O   1 
ATOM   2838 C CB  . CYS B 2 145 ? 135.748 145.040 159.118 1.00 56.76  ?  148 CYS B CB  1 
ATOM   2839 S SG  . CYS B 2 145 ? 137.010 143.753 159.248 1.00 56.76  ?  148 CYS B SG  1 
ATOM   2840 N N   . CYS B 2 146 ? 134.022 142.586 160.046 1.00 56.91  ?  149 CYS B N   1 
ATOM   2841 C CA  . CYS B 2 146 ? 133.497 141.801 161.152 1.00 56.91  ?  149 CYS B CA  1 
ATOM   2842 C C   . CYS B 2 146 ? 134.498 140.705 161.476 1.00 56.91  ?  149 CYS B C   1 
ATOM   2843 O O   . CYS B 2 146 ? 135.083 140.106 160.570 1.00 56.91  ?  149 CYS B O   1 
ATOM   2844 C CB  . CYS B 2 146 ? 132.130 141.193 160.819 1.00 56.91  ?  149 CYS B CB  1 
ATOM   2845 S SG  . CYS B 2 146 ? 132.074 140.270 159.269 1.00 56.91  ?  149 CYS B SG  1 
ATOM   2846 N N   . ARG B 2 147 ? 134.701 140.455 162.766 1.00 53.12  ?  150 ARG B N   1 
ATOM   2847 C CA  . ARG B 2 147 ? 135.631 139.429 163.210 1.00 53.12  ?  150 ARG B CA  1 
ATOM   2848 C C   . ARG B 2 147 ? 135.037 138.681 164.392 1.00 53.12  ?  150 ARG B C   1 
ATOM   2849 O O   . ARG B 2 147 ? 134.432 139.288 165.280 1.00 53.12  ?  150 ARG B O   1 
ATOM   2850 C CB  . ARG B 2 147 ? 136.988 140.029 163.594 1.00 53.12  ?  150 ARG B CB  1 
ATOM   2851 C CG  . ARG B 2 147 ? 137.885 140.331 162.407 1.00 53.12  ?  150 ARG B CG  1 
ATOM   2852 C CD  . ARG B 2 147 ? 138.120 139.092 161.564 1.00 53.12  ?  150 ARG B CD  1 
ATOM   2853 N NE  . ARG B 2 147 ? 138.884 139.389 160.359 1.00 53.12  ?  150 ARG B NE  1 
ATOM   2854 C CZ  . ARG B 2 147 ? 138.356 139.500 159.148 1.00 53.12  ?  150 ARG B CZ  1 
ATOM   2855 N NH1 . ARG B 2 147 ? 137.058 139.352 158.943 1.00 53.12  1  150 ARG B NH1 1 
ATOM   2856 N NH2 . ARG B 2 147 ? 139.151 139.769 158.117 1.00 53.12  ?  150 ARG B NH2 1 
ATOM   2857 N N   . PHE B 2 148 ? 135.219 137.365 164.398 1.00 52.56  ?  151 PHE B N   1 
ATOM   2858 C CA  . PHE B 2 148 ? 134.669 136.521 165.449 1.00 52.56  ?  151 PHE B CA  1 
ATOM   2859 C C   . PHE B 2 148 ? 135.619 136.459 166.637 1.00 52.56  ?  151 PHE B C   1 
ATOM   2860 O O   . PHE B 2 148 ? 136.804 136.150 166.480 1.00 52.56  ?  151 PHE B O   1 
ATOM   2861 C CB  . PHE B 2 148 ? 134.415 135.112 164.919 1.00 52.56  ?  151 PHE B CB  1 
ATOM   2862 C CG  . PHE B 2 148 ? 133.023 134.892 164.408 1.00 52.56  ?  151 PHE B CG  1 
ATOM   2863 C CD1 . PHE B 2 148 ? 131.981 134.647 165.282 1.00 52.56  ?  151 PHE B CD1 1 
ATOM   2864 C CD2 . PHE B 2 148 ? 132.760 134.908 163.050 1.00 52.56  ?  151 PHE B CD2 1 
ATOM   2865 C CE1 . PHE B 2 148 ? 130.703 134.435 164.814 1.00 52.56  ?  151 PHE B CE1 1 
ATOM   2866 C CE2 . PHE B 2 148 ? 131.483 134.696 162.578 1.00 52.56  ?  151 PHE B CE2 1 
ATOM   2867 C CZ  . PHE B 2 148 ? 130.454 134.461 163.461 1.00 52.56  ?  151 PHE B CZ  1 
ATOM   2868 N N   . LEU B 2 149 ? 135.098 136.755 167.827 1.00 59.17  ?  152 LEU B N   1 
ATOM   2869 C CA  . LEU B 2 149 ? 135.850 136.498 169.050 1.00 59.17  ?  152 LEU B CA  1 
ATOM   2870 C C   . LEU B 2 149 ? 135.731 135.035 169.454 1.00 59.17  ?  152 LEU B C   1 
ATOM   2871 O O   . LEU B 2 149 ? 136.738 134.360 169.691 1.00 59.17  ?  152 LEU B O   1 
ATOM   2872 C CB  . LEU B 2 149 ? 135.355 137.406 170.175 1.00 59.17  ?  152 LEU B CB  1 
ATOM   2873 C CG  . LEU B 2 149 ? 136.129 138.703 170.393 1.00 59.17  ?  152 LEU B CG  1 
ATOM   2874 C CD1 . LEU B 2 149 ? 135.846 139.671 169.270 1.00 59.17  ?  152 LEU B CD1 1 
ATOM   2875 C CD2 . LEU B 2 149 ? 135.775 139.318 171.734 1.00 59.17  ?  152 LEU B CD2 1 
ATOM   2876 N N   . ASP B 2 150 ? 134.504 134.538 169.536 1.00 65.38  ?  153 ASP B N   1 
ATOM   2877 C CA  . ASP B 2 150 ? 134.222 133.129 169.765 1.00 65.38  ?  153 ASP B CA  1 
ATOM   2878 C C   . ASP B 2 150 ? 132.894 132.820 169.083 1.00 65.38  ?  153 ASP B C   1 
ATOM   2879 O O   . ASP B 2 150 ? 132.422 133.594 168.243 1.00 65.38  ?  153 ASP B O   1 
ATOM   2880 C CB  . ASP B 2 150 ? 134.228 132.810 171.270 1.00 65.38  ?  153 ASP B CB  1 
ATOM   2881 C CG  . ASP B 2 150 ? 133.306 133.713 172.061 1.00 65.38  ?  153 ASP B CG  1 
ATOM   2882 O OD1 . ASP B 2 150 ? 132.076 133.512 171.996 1.00 65.38  ?  153 ASP B OD1 1 
ATOM   2883 O OD2 . ASP B 2 150 ? 133.811 134.623 172.750 1.00 65.38  -1 153 ASP B OD2 1 
ATOM   2884 N N   . ASP B 2 151 ? 132.284 131.691 169.438 1.00 67.52  ?  154 ASP B N   1 
ATOM   2885 C CA  . ASP B 2 151 ? 131.008 131.321 168.841 1.00 67.52  ?  154 ASP B CA  1 
ATOM   2886 C C   . ASP B 2 151 ? 129.860 132.219 169.282 1.00 67.52  ?  154 ASP B C   1 
ATOM   2887 O O   . ASP B 2 151 ? 128.777 132.139 168.693 1.00 67.52  ?  154 ASP B O   1 
ATOM   2888 C CB  . ASP B 2 151 ? 130.676 129.865 169.172 1.00 67.52  ?  154 ASP B CB  1 
ATOM   2889 C CG  . ASP B 2 151 ? 131.318 128.889 168.208 1.00 67.52  ?  154 ASP B CG  1 
ATOM   2890 O OD1 . ASP B 2 151 ? 131.597 129.285 167.058 1.00 67.52  ?  154 ASP B OD1 1 
ATOM   2891 O OD2 . ASP B 2 151 ? 131.542 127.725 168.600 1.00 67.52  -1 154 ASP B OD2 1 
ATOM   2892 N N   . ASN B 2 152 ? 130.062 133.069 170.291 1.00 68.70  ?  155 ASN B N   1 
ATOM   2893 C CA  . ASN B 2 152 ? 128.984 133.874 170.846 1.00 68.70  ?  155 ASN B CA  1 
ATOM   2894 C C   . ASN B 2 152 ? 129.197 135.378 170.742 1.00 68.70  ?  155 ASN B C   1 
ATOM   2895 O O   . ASN B 2 152 ? 128.218 136.124 170.845 1.00 68.70  ?  155 ASN B O   1 
ATOM   2896 C CB  . ASN B 2 152 ? 128.758 133.512 172.323 1.00 68.70  ?  155 ASN B CB  1 
ATOM   2897 C CG  . ASN B 2 152 ? 127.436 134.024 172.852 1.00 68.70  ?  155 ASN B CG  1 
ATOM   2898 O OD1 . ASN B 2 152 ? 126.386 133.801 172.252 1.00 68.70  ?  155 ASN B OD1 1 
ATOM   2899 N ND2 . ASN B 2 152 ? 127.481 134.720 173.982 1.00 68.70  ?  155 ASN B ND2 1 
ATOM   2900 N N   . GLN B 2 153 ? 130.426 135.846 170.542 1.00 63.31  ?  156 GLN B N   1 
ATOM   2901 C CA  . GLN B 2 153 ? 130.722 137.269 170.477 1.00 63.31  ?  156 GLN B CA  1 
ATOM   2902 C C   . GLN B 2 153 ? 131.339 137.614 169.129 1.00 63.31  ?  156 GLN B C   1 
ATOM   2903 O O   . GLN B 2 153 ? 132.064 136.809 168.539 1.00 63.31  ?  156 GLN B O   1 
ATOM   2904 C CB  . GLN B 2 153 ? 131.673 137.690 171.601 1.00 63.31  ?  156 GLN B CB  1 
ATOM   2905 C CG  . GLN B 2 153 ? 131.164 137.379 172.994 1.00 63.31  ?  156 GLN B CG  1 
ATOM   2906 C CD  . GLN B 2 153 ? 131.787 138.268 174.047 1.00 63.31  ?  156 GLN B CD  1 
ATOM   2907 O OE1 . GLN B 2 153 ? 132.989 138.197 174.303 1.00 63.31  ?  156 GLN B OE1 1 
ATOM   2908 N NE2 . GLN B 2 153 ? 130.972 139.114 174.665 1.00 63.31  ?  156 GLN B NE2 1 
ATOM   2909 N N   . ILE B 2 154 ? 131.047 138.818 168.643 1.00 54.81  ?  157 ILE B N   1 
ATOM   2910 C CA  . ILE B 2 154 ? 131.588 139.259 167.358 1.00 54.81  ?  157 ILE B CA  1 
ATOM   2911 C C   . ILE B 2 154 ? 131.719 140.776 167.357 1.00 54.81  ?  157 ILE B C   1 
ATOM   2912 O O   . ILE B 2 154 ? 130.800 141.486 167.769 1.00 54.81  ?  157 ILE B O   1 
ATOM   2913 C CB  . ILE B 2 154 ? 130.714 138.775 166.182 1.00 54.81  ?  157 ILE B CB  1 
ATOM   2914 C CG1 . ILE B 2 154 ? 131.221 139.346 164.857 1.00 54.81  ?  157 ILE B CG1 1 
ATOM   2915 C CG2 . ILE B 2 154 ? 129.254 139.134 166.407 1.00 54.81  ?  157 ILE B CG2 1 
ATOM   2916 C CD1 . ILE B 2 154 ? 130.691 138.624 163.643 1.00 54.81  ?  157 ILE B CD1 1 
ATOM   2917 N N   . VAL B 2 155 ? 132.860 141.279 166.887 1.00 53.91  ?  158 VAL B N   1 
ATOM   2918 C CA  . VAL B 2 155 ? 133.077 142.715 166.732 1.00 53.91  ?  158 VAL B CA  1 
ATOM   2919 C C   . VAL B 2 155 ? 132.897 143.095 165.271 1.00 53.91  ?  158 VAL B C   1 
ATOM   2920 O O   . VAL B 2 155 ? 133.371 142.396 164.366 1.00 53.91  ?  158 VAL B O   1 
ATOM   2921 C CB  . VAL B 2 155 ? 134.462 143.149 167.255 1.00 53.91  ?  158 VAL B CB  1 
ATOM   2922 C CG1 . VAL B 2 155 ? 134.563 142.904 168.741 1.00 53.91  ?  158 VAL B CG1 1 
ATOM   2923 C CG2 . VAL B 2 155 ? 135.568 142.401 166.533 1.00 53.91  ?  158 VAL B CG2 1 
ATOM   2924 N N   . THR B 2 156 ? 132.185 144.193 165.040 1.00 56.54  ?  159 THR B N   1 
ATOM   2925 C CA  . THR B 2 156 ? 131.920 144.702 163.705 1.00 56.54  ?  159 THR B CA  1 
ATOM   2926 C C   . THR B 2 156 ? 132.259 146.183 163.650 1.00 56.54  ?  159 THR B C   1 
ATOM   2927 O O   . THR B 2 156 ? 132.177 146.894 164.655 1.00 56.54  ?  159 THR B O   1 
ATOM   2928 C CB  . THR B 2 156 ? 130.453 144.502 163.299 1.00 56.54  ?  159 THR B CB  1 
ATOM   2929 O OG1 . THR B 2 156 ? 129.600 145.145 164.253 1.00 56.54  ?  159 THR B OG1 1 
ATOM   2930 C CG2 . THR B 2 156 ? 130.108 143.025 163.238 1.00 56.54  ?  159 THR B CG2 1 
ATOM   2931 N N   . SER B 2 157 ? 132.650 146.640 162.465 1.00 56.97  ?  160 SER B N   1 
ATOM   2932 C CA  . SER B 2 157 ? 132.885 148.050 162.198 1.00 56.97  ?  160 SER B CA  1 
ATOM   2933 C C   . SER B 2 157 ? 132.001 148.482 161.040 1.00 56.97  ?  160 SER B C   1 
ATOM   2934 O O   . SER B 2 157 ? 131.831 147.739 160.070 1.00 56.97  ?  160 SER B O   1 
ATOM   2935 C CB  . SER B 2 157 ? 134.352 148.321 161.864 1.00 56.97  ?  160 SER B CB  1 
ATOM   2936 O OG  . SER B 2 157 ? 134.700 147.758 160.614 1.00 56.97  ?  160 SER B OG  1 
ATOM   2937 N N   . SER B 2 158 ? 131.436 149.680 161.141 1.00 60.67  ?  161 SER B N   1 
ATOM   2938 C CA  . SER B 2 158 ? 130.495 150.168 160.146 1.00 60.67  ?  161 SER B CA  1 
ATOM   2939 C C   . SER B 2 158 ? 130.898 151.567 159.702 1.00 60.67  ?  161 SER B C   1 
ATOM   2940 O O   . SER B 2 158 ? 131.849 152.162 160.216 1.00 60.67  ?  161 SER B O   1 
ATOM   2941 C CB  . SER B 2 158 ? 129.062 150.160 160.690 1.00 60.67  ?  161 SER B CB  1 
ATOM   2942 O OG  . SER B 2 158 ? 129.008 150.727 161.984 1.00 60.67  ?  161 SER B OG  1 
ATOM   2943 N N   . GLY B 2 159 ? 130.157 152.092 158.731 1.00 62.41  ?  162 GLY B N   1 
ATOM   2944 C CA  . GLY B 2 159 ? 130.378 153.421 158.207 1.00 62.41  ?  162 GLY B CA  1 
ATOM   2945 C C   . GLY B 2 159 ? 129.797 154.541 159.030 1.00 62.41  ?  162 GLY B C   1 
ATOM   2946 O O   . GLY B 2 159 ? 129.899 155.706 158.636 1.00 62.41  ?  162 GLY B O   1 
ATOM   2947 N N   . ASP B 2 160 ? 129.175 154.227 160.165 1.00 63.88  ?  163 ASP B N   1 
ATOM   2948 C CA  . ASP B 2 160 ? 128.669 155.235 161.084 1.00 63.88  ?  163 ASP B CA  1 
ATOM   2949 C C   . ASP B 2 160 ? 129.716 155.669 162.103 1.00 63.88  ?  163 ASP B C   1 
ATOM   2950 O O   . ASP B 2 160 ? 129.354 156.166 163.176 1.00 63.88  ?  163 ASP B O   1 
ATOM   2951 C CB  . ASP B 2 160 ? 127.415 154.720 161.792 1.00 63.88  ?  163 ASP B CB  1 
ATOM   2952 C CG  . ASP B 2 160 ? 127.701 153.547 162.703 1.00 63.88  ?  163 ASP B CG  1 
ATOM   2953 O OD1 . ASP B 2 160 ? 128.696 152.837 162.461 1.00 63.88  ?  163 ASP B OD1 1 
ATOM   2954 O OD2 . ASP B 2 160 ? 126.929 153.334 163.660 1.00 63.88  -1 163 ASP B OD2 1 
ATOM   2955 N N   . THR B 2 161 ? 131.000 155.480 161.790 1.00 62.61  ?  164 THR B N   1 
ATOM   2956 C CA  . THR B 2 161 ? 132.119 155.929 162.622 1.00 62.61  ?  164 THR B CA  1 
ATOM   2957 C C   . THR B 2 161 ? 132.120 155.269 163.998 1.00 62.61  ?  164 THR B C   1 
ATOM   2958 O O   . THR B 2 161 ? 132.665 155.819 164.958 1.00 62.61  ?  164 THR B O   1 
ATOM   2959 C CB  . THR B 2 161 ? 132.136 157.456 162.770 1.00 62.61  ?  164 THR B CB  1 
ATOM   2960 O OG1 . THR B 2 161 ? 131.118 157.860 163.693 1.00 62.61  ?  164 THR B OG1 1 
ATOM   2961 C CG2 . THR B 2 161 ? 131.898 158.134 161.429 1.00 62.61  ?  164 THR B CG2 1 
ATOM   2962 N N   . THR B 2 162 ? 131.515 154.088 164.115 1.00 61.22  ?  165 THR B N   1 
ATOM   2963 C CA  . THR B 2 162 ? 131.476 153.369 165.381 1.00 61.22  ?  165 THR B CA  1 
ATOM   2964 C C   . THR B 2 162 ? 131.769 151.896 165.142 1.00 61.22  ?  165 THR B C   1 
ATOM   2965 O O   . THR B 2 162 ? 131.549 151.363 164.052 1.00 61.22  ?  165 THR B O   1 
ATOM   2966 C CB  . THR B 2 162 ? 130.119 153.502 166.091 1.00 61.22  ?  165 THR B CB  1 
ATOM   2967 O OG1 . THR B 2 162 ? 129.102 152.867 165.307 1.00 61.22  ?  165 THR B OG1 1 
ATOM   2968 C CG2 . THR B 2 162 ? 129.752 154.962 166.311 1.00 61.22  ?  165 THR B CG2 1 
ATOM   2969 N N   . CYS B 2 163 ? 132.273 151.244 166.184 1.00 64.27  ?  166 CYS B N   1 
ATOM   2970 C CA  . CYS B 2 163 ? 132.425 149.798 166.224 1.00 64.27  ?  166 CYS B CA  1 
ATOM   2971 C C   . CYS B 2 163 ? 131.497 149.229 167.288 1.00 64.27  ?  166 CYS B C   1 
ATOM   2972 O O   . CYS B 2 163 ? 131.074 149.930 168.208 1.00 64.27  ?  166 CYS B O   1 
ATOM   2973 C CB  . CYS B 2 163 ? 133.875 149.399 166.515 1.00 64.27  ?  166 CYS B CB  1 
ATOM   2974 S SG  . CYS B 2 163 ? 135.050 149.836 165.214 1.00 64.27  ?  166 CYS B SG  1 
ATOM   2975 N N   . ALA B 2 164 ? 131.182 147.944 167.164 1.00 60.40  ?  167 ALA B N   1 
ATOM   2976 C CA  . ALA B 2 164 ? 130.234 147.335 168.086 1.00 60.40  ?  167 ALA B CA  1 
ATOM   2977 C C   . ALA B 2 164 ? 130.622 145.894 168.371 1.00 60.40  ?  167 ALA B C   1 
ATOM   2978 O O   . ALA B 2 164 ? 130.890 145.125 167.445 1.00 60.40  ?  167 ALA B O   1 
ATOM   2979 C CB  . ALA B 2 164 ? 128.810 147.397 167.527 1.00 60.40  ?  167 ALA B CB  1 
ATOM   2980 N N   . LEU B 2 165 ? 130.638 145.537 169.651 1.00 61.05  ?  168 LEU B N   1 
ATOM   2981 C CA  . LEU B 2 165 ? 130.812 144.161 170.093 1.00 61.05  ?  168 LEU B CA  1 
ATOM   2982 C C   . LEU B 2 165 ? 129.441 143.600 170.443 1.00 61.05  ?  168 LEU B C   1 
ATOM   2983 O O   . LEU B 2 165 ? 128.779 144.100 171.361 1.00 61.05  ?  168 LEU B O   1 
ATOM   2984 C CB  . LEU B 2 165 ? 131.752 144.085 171.295 1.00 61.05  ?  168 LEU B CB  1 
ATOM   2985 C CG  . LEU B 2 165 ? 131.716 142.794 172.115 1.00 61.05  ?  168 LEU B CG  1 
ATOM   2986 C CD1 . LEU B 2 165 ? 132.490 141.685 171.426 1.00 61.05  ?  168 LEU B CD1 1 
ATOM   2987 C CD2 . LEU B 2 165 ? 132.256 143.036 173.513 1.00 61.05  ?  168 LEU B CD2 1 
ATOM   2988 N N   . TRP B 2 166 ? 129.026 142.568 169.711 1.00 62.49  ?  169 TRP B N   1 
ATOM   2989 C CA  . TRP B 2 166 ? 127.710 141.962 169.819 1.00 62.49  ?  169 TRP B CA  1 
ATOM   2990 C C   . TRP B 2 166 ? 127.808 140.602 170.490 1.00 62.49  ?  169 TRP B C   1 
ATOM   2991 O O   . TRP B 2 166 ? 128.728 139.822 170.208 1.00 62.49  ?  169 TRP B O   1 
ATOM   2992 C CB  . TRP B 2 166 ? 127.066 141.766 168.443 1.00 62.49  ?  169 TRP B CB  1 
ATOM   2993 C CG  . TRP B 2 166 ? 127.113 142.939 167.525 1.00 62.49  ?  169 TRP B CG  1 
ATOM   2994 C CD1 . TRP B 2 166 ? 128.208 143.439 166.885 1.00 62.49  ?  169 TRP B CD1 1 
ATOM   2995 C CD2 . TRP B 2 166 ? 126.002 143.732 167.099 1.00 62.49  ?  169 TRP B CD2 1 
ATOM   2996 N NE1 . TRP B 2 166 ? 127.851 144.511 166.106 1.00 62.49  ?  169 TRP B NE1 1 
ATOM   2997 C CE2 . TRP B 2 166 ? 126.500 144.710 166.219 1.00 62.49  ?  169 TRP B CE2 1 
ATOM   2998 C CE3 . TRP B 2 166 ? 124.635 143.716 167.386 1.00 62.49  ?  169 TRP B CE3 1 
ATOM   2999 C CZ2 . TRP B 2 166 ? 125.681 145.663 165.624 1.00 62.49  ?  169 TRP B CZ2 1 
ATOM   3000 C CZ3 . TRP B 2 166 ? 123.824 144.661 166.795 1.00 62.49  ?  169 TRP B CZ3 1 
ATOM   3001 C CH2 . TRP B 2 166 ? 124.349 145.622 165.924 1.00 62.49  ?  169 TRP B CH2 1 
ATOM   3002 N N   . ASP B 2 167 ? 126.845 140.325 171.366 1.00 70.70  ?  170 ASP B N   1 
ATOM   3003 C CA  . ASP B 2 167 ? 126.587 138.981 171.866 1.00 70.70  ?  170 ASP B CA  1 
ATOM   3004 C C   . ASP B 2 167 ? 125.579 138.331 170.925 1.00 70.70  ?  170 ASP B C   1 
ATOM   3005 O O   . ASP B 2 167 ? 124.439 138.792 170.812 1.00 70.70  ?  170 ASP B O   1 
ATOM   3006 C CB  . ASP B 2 167 ? 126.066 139.031 173.300 1.00 70.70  ?  170 ASP B CB  1 
ATOM   3007 C CG  . ASP B 2 167 ? 125.500 137.705 173.763 1.00 70.70  ?  170 ASP B CG  1 
ATOM   3008 O OD1 . ASP B 2 167 ? 126.080 136.655 173.420 1.00 70.70  ?  170 ASP B OD1 1 
ATOM   3009 O OD2 . ASP B 2 167 ? 124.475 137.714 174.475 1.00 70.70  -1 170 ASP B OD2 1 
ATOM   3010 N N   . ILE B 2 168 ? 126.001 137.263 170.244 1.00 67.13  ?  171 ILE B N   1 
ATOM   3011 C CA  . ILE B 2 168 ? 125.199 136.701 169.161 1.00 67.13  ?  171 ILE B CA  1 
ATOM   3012 C C   . ILE B 2 168 ? 123.894 136.117 169.690 1.00 67.13  ?  171 ILE B C   1 
ATOM   3013 O O   . ILE B 2 168 ? 122.834 136.278 169.072 1.00 67.13  ?  171 ILE B O   1 
ATOM   3014 C CB  . ILE B 2 168 ? 126.015 135.653 168.384 1.00 67.13  ?  171 ILE B CB  1 
ATOM   3015 C CG1 . ILE B 2 168 ? 127.212 136.315 167.703 1.00 67.13  ?  171 ILE B CG1 1 
ATOM   3016 C CG2 . ILE B 2 168 ? 125.144 134.949 167.358 1.00 67.13  ?  171 ILE B CG2 1 
ATOM   3017 C CD1 . ILE B 2 168 ? 127.923 135.419 166.721 1.00 67.13  ?  171 ILE B CD1 1 
ATOM   3018 N N   . GLU B 2 169 ? 123.945 135.429 170.833 1.00 74.45  ?  172 GLU B N   1 
ATOM   3019 C CA  . GLU B 2 169 ? 122.758 134.749 171.343 1.00 74.45  ?  172 GLU B CA  1 
ATOM   3020 C C   . GLU B 2 169 ? 121.630 135.735 171.623 1.00 74.45  ?  172 GLU B C   1 
ATOM   3021 O O   . GLU B 2 169 ? 120.485 135.520 171.211 1.00 74.45  ?  172 GLU B O   1 
ATOM   3022 C CB  . GLU B 2 169 ? 123.109 133.959 172.604 1.00 74.45  ?  172 GLU B CB  1 
ATOM   3023 C CG  . GLU B 2 169 ? 121.986 133.071 173.111 1.00 74.45  ?  172 GLU B CG  1 
ATOM   3024 C CD  . GLU B 2 169 ? 121.283 133.655 174.320 1.00 74.45  ?  172 GLU B CD  1 
ATOM   3025 O OE1 . GLU B 2 169 ? 121.980 134.111 175.251 1.00 74.45  ?  172 GLU B OE1 1 
ATOM   3026 O OE2 . GLU B 2 169 ? 120.034 133.657 174.340 1.00 74.45  -1 172 GLU B OE2 1 
ATOM   3027 N N   . THR B 2 170 ? 121.936 136.829 172.322 1.00 73.24  ?  173 THR B N   1 
ATOM   3028 C CA  . THR B 2 170 ? 120.921 137.842 172.587 1.00 73.24  ?  173 THR B CA  1 
ATOM   3029 C C   . THR B 2 170 ? 120.650 138.714 171.368 1.00 73.24  ?  173 THR B C   1 
ATOM   3030 O O   . THR B 2 170 ? 119.529 139.207 171.203 1.00 73.24  ?  173 THR B O   1 
ATOM   3031 C CB  . THR B 2 170 ? 121.339 138.716 173.770 1.00 73.24  ?  173 THR B CB  1 
ATOM   3032 O OG1 . THR B 2 170 ? 122.700 139.131 173.603 1.00 73.24  ?  173 THR B OG1 1 
ATOM   3033 C CG2 . THR B 2 170 ? 121.203 137.946 175.074 1.00 73.24  ?  173 THR B CG2 1 
ATOM   3034 N N   . GLY B 2 171 ? 121.650 138.915 170.513 1.00 71.82  ?  174 GLY B N   1 
ATOM   3035 C CA  . GLY B 2 171 ? 121.488 139.750 169.342 1.00 71.82  ?  174 GLY B CA  1 
ATOM   3036 C C   . GLY B 2 171 ? 121.642 141.234 169.583 1.00 71.82  ?  174 GLY B C   1 
ATOM   3037 O O   . GLY B 2 171 ? 121.366 142.023 168.673 1.00 71.82  ?  174 GLY B O   1 
ATOM   3038 N N   . GLN B 2 172 ? 122.074 141.640 170.772 1.00 74.12  ?  175 GLN B N   1 
ATOM   3039 C CA  . GLN B 2 172 ? 122.218 143.042 171.127 1.00 74.12  ?  175 GLN B CA  1 
ATOM   3040 C C   . GLN B 2 172 ? 123.688 143.442 171.133 1.00 74.12  ?  175 GLN B C   1 
ATOM   3041 O O   . GLN B 2 172 ? 124.586 142.597 171.164 1.00 74.12  ?  175 GLN B O   1 
ATOM   3042 C CB  . GLN B 2 172 ? 121.596 143.325 172.498 1.00 74.12  ?  175 GLN B CB  1 
ATOM   3043 C CG  . GLN B 2 172 ? 120.165 142.839 172.643 1.00 74.12  ?  175 GLN B CG  1 
ATOM   3044 C CD  . GLN B 2 172 ? 119.196 143.612 171.772 1.00 74.12  ?  175 GLN B CD  1 
ATOM   3045 O OE1 . GLN B 2 172 ? 118.647 143.079 170.808 1.00 74.12  ?  175 GLN B OE1 1 
ATOM   3046 N NE2 . GLN B 2 172 ? 118.980 144.878 172.109 1.00 74.12  ?  175 GLN B NE2 1 
ATOM   3047 N N   . GLN B 2 173 ? 123.923 144.752 171.106 1.00 68.63  ?  176 GLN B N   1 
ATOM   3048 C CA  . GLN B 2 173 ? 125.275 145.293 171.178 1.00 68.63  ?  176 GLN B CA  1 
ATOM   3049 C C   . GLN B 2 173 ? 125.744 145.255 172.626 1.00 68.63  ?  176 GLN B C   1 
ATOM   3050 O O   . GLN B 2 173 ? 125.290 146.051 173.454 1.00 68.63  ?  176 GLN B O   1 
ATOM   3051 C CB  . GLN B 2 173 ? 125.319 146.719 170.636 1.00 68.63  ?  176 GLN B CB  1 
ATOM   3052 C CG  . GLN B 2 173 ? 125.232 146.824 169.130 1.00 68.63  ?  176 GLN B CG  1 
ATOM   3053 C CD  . GLN B 2 173 ? 125.329 148.255 168.645 1.00 68.63  ?  176 GLN B CD  1 
ATOM   3054 O OE1 . GLN B 2 173 ? 125.369 149.190 169.443 1.00 68.63  ?  176 GLN B OE1 1 
ATOM   3055 N NE2 . GLN B 2 173 ? 125.369 148.434 167.331 1.00 68.63  ?  176 GLN B NE2 1 
ATOM   3056 N N   . THR B 2 174 ? 126.650 144.326 172.936 1.00 67.53  ?  177 THR B N   1 
ATOM   3057 C CA  . THR B 2 174 ? 127.222 144.282 174.277 1.00 67.53  ?  177 THR B CA  1 
ATOM   3058 C C   . THR B 2 174 ? 128.013 145.549 174.574 1.00 67.53  ?  177 THR B C   1 
ATOM   3059 O O   . THR B 2 174 ? 127.905 146.117 175.667 1.00 67.53  ?  177 THR B O   1 
ATOM   3060 C CB  . THR B 2 174 ? 128.109 143.046 174.430 1.00 67.53  ?  177 THR B CB  1 
ATOM   3061 O OG1 . THR B 2 174 ? 127.305 141.865 174.325 1.00 67.53  ?  177 THR B OG1 1 
ATOM   3062 C CG2 . THR B 2 174 ? 128.809 143.053 175.780 1.00 67.53  ?  177 THR B CG2 1 
ATOM   3063 N N   . THR B 2 175 ? 128.803 146.016 173.609 1.00 67.54  ?  178 THR B N   1 
ATOM   3064 C CA  . THR B 2 175 ? 129.616 147.209 173.799 1.00 67.54  ?  178 THR B CA  1 
ATOM   3065 C C   . THR B 2 175 ? 129.623 148.033 172.519 1.00 67.54  ?  178 THR B C   1 
ATOM   3066 O O   . THR B 2 175 ? 129.506 147.494 171.418 1.00 67.54  ?  178 THR B O   1 
ATOM   3067 C CB  . THR B 2 175 ? 131.056 146.851 174.201 1.00 67.54  ?  178 THR B CB  1 
ATOM   3068 O OG1 . THR B 2 175 ? 131.035 145.783 175.155 1.00 67.54  ?  178 THR B OG1 1 
ATOM   3069 C CG2 . THR B 2 175 ? 131.756 148.050 174.821 1.00 67.54  ?  178 THR B CG2 1 
ATOM   3070 N N   . THR B 2 176 ? 129.766 149.348 172.674 1.00 67.19  ?  179 THR B N   1 
ATOM   3071 C CA  . THR B 2 176 ? 129.863 150.265 171.544 1.00 67.19  ?  179 THR B CA  1 
ATOM   3072 C C   . THR B 2 176 ? 131.129 151.094 171.693 1.00 67.19  ?  179 THR B C   1 
ATOM   3073 O O   . THR B 2 176 ? 131.314 151.769 172.711 1.00 67.19  ?  179 THR B O   1 
ATOM   3074 C CB  . THR B 2 176 ? 128.634 151.174 171.457 1.00 67.19  ?  179 THR B CB  1 
ATOM   3075 O OG1 . THR B 2 176 ? 127.445 150.376 171.494 1.00 67.19  ?  179 THR B OG1 1 
ATOM   3076 C CG2 . THR B 2 176 ? 128.658 151.975 170.166 1.00 67.19  ?  179 THR B CG2 1 
ATOM   3077 N N   . PHE B 2 177 ? 131.993 151.044 170.684 1.00 65.26  ?  180 PHE B N   1 
ATOM   3078 C CA  . PHE B 2 177 ? 133.239 151.796 170.663 1.00 65.26  ?  180 PHE B CA  1 
ATOM   3079 C C   . PHE B 2 177 ? 133.063 153.008 169.756 1.00 65.26  ?  180 PHE B C   1 
ATOM   3080 O O   . PHE B 2 177 ? 132.795 152.857 168.558 1.00 65.26  ?  180 PHE B O   1 
ATOM   3081 C CB  . PHE B 2 177 ? 134.395 150.926 170.170 1.00 65.26  ?  180 PHE B CB  1 
ATOM   3082 C CG  . PHE B 2 177 ? 134.422 149.550 170.771 1.00 65.26  ?  180 PHE B CG  1 
ATOM   3083 C CD1 . PHE B 2 177 ? 135.092 149.310 171.957 1.00 65.26  ?  180 PHE B CD1 1 
ATOM   3084 C CD2 . PHE B 2 177 ? 133.789 148.493 170.141 1.00 65.26  ?  180 PHE B CD2 1 
ATOM   3085 C CE1 . PHE B 2 177 ? 135.121 148.045 172.506 1.00 65.26  ?  180 PHE B CE1 1 
ATOM   3086 C CE2 . PHE B 2 177 ? 133.815 147.227 170.688 1.00 65.26  ?  180 PHE B CE2 1 
ATOM   3087 C CZ  . PHE B 2 177 ? 134.482 147.003 171.871 1.00 65.26  ?  180 PHE B CZ  1 
ATOM   3088 N N   . THR B 2 178 ? 133.220 154.199 170.324 1.00 67.02  ?  181 THR B N   1 
ATOM   3089 C CA  . THR B 2 178 ? 133.059 155.448 169.598 1.00 67.02  ?  181 THR B CA  1 
ATOM   3090 C C   . THR B 2 178 ? 134.306 156.308 169.758 1.00 67.02  ?  181 THR B C   1 
ATOM   3091 O O   . THR B 2 178 ? 135.087 156.140 170.698 1.00 67.02  ?  181 THR B O   1 
ATOM   3092 C CB  . THR B 2 178 ? 131.830 156.227 170.086 1.00 67.02  ?  181 THR B CB  1 
ATOM   3093 O OG1 . THR B 2 178 ? 132.004 156.585 171.462 1.00 67.02  ?  181 THR B OG1 1 
ATOM   3094 C CG2 . THR B 2 178 ? 130.571 155.388 169.941 1.00 67.02  ?  181 THR B CG2 1 
ATOM   3095 N N   . GLY B 2 179 ? 134.477 157.244 168.830 1.00 66.54  ?  182 GLY B N   1 
ATOM   3096 C CA  . GLY B 2 179 ? 135.623 158.130 168.857 1.00 66.54  ?  182 GLY B CA  1 
ATOM   3097 C C   . GLY B 2 179 ? 136.169 158.461 167.485 1.00 66.54  ?  182 GLY B C   1 
ATOM   3098 O O   . GLY B 2 179 ? 136.786 159.513 167.297 1.00 66.54  ?  182 GLY B O   1 
ATOM   3099 N N   . HIS B 2 180 ? 135.952 157.576 166.516 1.00 63.74  ?  183 HIS B N   1 
ATOM   3100 C CA  . HIS B 2 180 ? 136.349 157.867 165.147 1.00 63.74  ?  183 HIS B CA  1 
ATOM   3101 C C   . HIS B 2 180 ? 135.478 158.973 164.565 1.00 63.74  ?  183 HIS B C   1 
ATOM   3102 O O   . HIS B 2 180 ? 134.269 159.028 164.807 1.00 63.74  ?  183 HIS B O   1 
ATOM   3103 C CB  . HIS B 2 180 ? 136.247 156.616 164.276 1.00 63.74  ?  183 HIS B CB  1 
ATOM   3104 C CG  . HIS B 2 180 ? 137.385 155.660 164.449 1.00 63.74  ?  183 HIS B CG  1 
ATOM   3105 N ND1 . HIS B 2 180 ? 138.679 155.975 164.098 1.00 63.74  ?  183 HIS B ND1 1 
ATOM   3106 C CD2 . HIS B 2 180 ? 137.419 154.389 164.913 1.00 63.74  ?  183 HIS B CD2 1 
ATOM   3107 C CE1 . HIS B 2 180 ? 139.464 154.942 164.348 1.00 63.74  ?  183 HIS B CE1 1 
ATOM   3108 N NE2 . HIS B 2 180 ? 138.725 153.968 164.845 1.00 63.74  ?  183 HIS B NE2 1 
ATOM   3109 N N   . THR B 2 181 ? 136.101 159.862 163.795 1.00 67.11  ?  184 THR B N   1 
ATOM   3110 C CA  . THR B 2 181 ? 135.390 160.921 163.096 1.00 67.11  ?  184 THR B CA  1 
ATOM   3111 C C   . THR B 2 181 ? 135.161 160.594 161.627 1.00 67.11  ?  184 THR B C   1 
ATOM   3112 O O   . THR B 2 181 ? 134.678 161.449 160.878 1.00 67.11  ?  184 THR B O   1 
ATOM   3113 C CB  . THR B 2 181 ? 136.147 162.244 163.225 1.00 67.11  ?  184 THR B CB  1 
ATOM   3114 O OG1 . THR B 2 181 ? 137.439 162.120 162.620 1.00 67.11  ?  184 THR B OG1 1 
ATOM   3115 C CG2 . THR B 2 181 ? 136.316 162.618 164.689 1.00 67.11  ?  184 THR B CG2 1 
ATOM   3116 N N   . GLY B 2 182 ? 135.495 159.376 161.199 1.00 65.52  ?  185 GLY B N   1 
ATOM   3117 C CA  . GLY B 2 182 ? 135.281 158.950 159.833 1.00 65.52  ?  185 GLY B CA  1 
ATOM   3118 C C   . GLY B 2 182 ? 134.859 157.495 159.789 1.00 65.52  ?  185 GLY B C   1 
ATOM   3119 O O   . GLY B 2 182 ? 134.845 156.805 160.809 1.00 65.52  ?  185 GLY B O   1 
ATOM   3120 N N   . ASP B 2 183 ? 134.510 157.043 158.587 1.00 65.66  ?  186 ASP B N   1 
ATOM   3121 C CA  . ASP B 2 183 ? 134.050 155.673 158.411 1.00 65.66  ?  186 ASP B CA  1 
ATOM   3122 C C   . ASP B 2 183 ? 135.155 154.691 158.776 1.00 65.66  ?  186 ASP B C   1 
ATOM   3123 O O   . ASP B 2 183 ? 136.292 154.820 158.315 1.00 65.66  ?  186 ASP B O   1 
ATOM   3124 C CB  . ASP B 2 183 ? 133.607 155.446 156.967 1.00 65.66  ?  186 ASP B CB  1 
ATOM   3125 C CG  . ASP B 2 183 ? 132.586 156.462 156.505 1.00 65.66  ?  186 ASP B CG  1 
ATOM   3126 O OD1 . ASP B 2 183 ? 131.936 157.089 157.366 1.00 65.66  ?  186 ASP B OD1 1 
ATOM   3127 O OD2 . ASP B 2 183 ? 132.429 156.630 155.279 1.00 65.66  -1 186 ASP B OD2 1 
ATOM   3128 N N   . VAL B 2 184 ? 134.816 153.701 159.596 1.00 57.74  ?  187 VAL B N   1 
ATOM   3129 C CA  . VAL B 2 184 ? 135.769 152.667 159.982 1.00 57.74  ?  187 VAL B CA  1 
ATOM   3130 C C   . VAL B 2 184 ? 135.789 151.604 158.892 1.00 57.74  ?  187 VAL B C   1 
ATOM   3131 O O   . VAL B 2 184 ? 134.769 150.966 158.616 1.00 57.74  ?  187 VAL B O   1 
ATOM   3132 C CB  . VAL B 2 184 ? 135.407 152.059 161.344 1.00 57.74  ?  187 VAL B CB  1 
ATOM   3133 C CG1 . VAL B 2 184 ? 136.554 151.215 161.863 1.00 57.74  ?  187 VAL B CG1 1 
ATOM   3134 C CG2 . VAL B 2 184 ? 135.058 153.153 162.334 1.00 57.74  ?  187 VAL B CG2 1 
ATOM   3135 N N   . MET B 2 185 ? 136.950 151.411 158.269 1.00 58.49  ?  188 MET B N   1 
ATOM   3136 C CA  . MET B 2 185 ? 137.037 150.544 157.102 1.00 58.49  ?  188 MET B CA  1 
ATOM   3137 C C   . MET B 2 185 ? 137.495 149.130 157.420 1.00 58.49  ?  188 MET B C   1 
ATOM   3138 O O   . MET B 2 185 ? 137.138 148.201 156.688 1.00 58.49  ?  188 MET B O   1 
ATOM   3139 C CB  . MET B 2 185 ? 137.982 151.153 156.059 1.00 58.49  ?  188 MET B CB  1 
ATOM   3140 C CG  . MET B 2 185 ? 137.591 152.549 155.583 1.00 58.49  ?  188 MET B CG  1 
ATOM   3141 S SD  . MET B 2 185 ? 135.863 152.774 155.105 1.00 58.49  ?  188 MET B SD  1 
ATOM   3142 C CE  . MET B 2 185 ? 135.556 151.325 154.093 1.00 58.49  ?  188 MET B CE  1 
ATOM   3143 N N   . SER B 2 186 ? 138.272 148.934 158.481 1.00 55.92  ?  189 SER B N   1 
ATOM   3144 C CA  . SER B 2 186 ? 138.755 147.601 158.808 1.00 55.92  ?  189 SER B CA  1 
ATOM   3145 C C   . SER B 2 186 ? 139.102 147.540 160.286 1.00 55.92  ?  189 SER B C   1 
ATOM   3146 O O   . SER B 2 186 ? 139.362 148.562 160.926 1.00 55.92  ?  189 SER B O   1 
ATOM   3147 C CB  . SER B 2 186 ? 139.971 147.222 157.957 1.00 55.92  ?  189 SER B CB  1 
ATOM   3148 O OG  . SER B 2 186 ? 140.179 145.821 157.961 1.00 55.92  ?  189 SER B OG  1 
ATOM   3149 N N   . LEU B 2 187 ? 139.100 146.320 160.817 1.00 53.89  ?  190 LEU B N   1 
ATOM   3150 C CA  . LEU B 2 187 ? 139.518 146.065 162.186 1.00 53.89  ?  190 LEU B CA  1 
ATOM   3151 C C   . LEU B 2 187 ? 140.276 144.748 162.234 1.00 53.89  ?  190 LEU B C   1 
ATOM   3152 O O   . LEU B 2 187 ? 140.067 143.863 161.401 1.00 53.89  ?  190 LEU B O   1 
ATOM   3153 C CB  . LEU B 2 187 ? 138.324 146.040 163.157 1.00 53.89  ?  190 LEU B CB  1 
ATOM   3154 C CG  . LEU B 2 187 ? 137.200 145.014 162.984 1.00 53.89  ?  190 LEU B CG  1 
ATOM   3155 C CD1 . LEU B 2 187 ? 137.520 143.700 163.673 1.00 53.89  ?  190 LEU B CD1 1 
ATOM   3156 C CD2 . LEU B 2 187 ? 135.901 145.575 163.521 1.00 53.89  ?  190 LEU B CD2 1 
ATOM   3157 N N   . SER B 2 188 ? 141.162 144.629 163.218 1.00 55.11  ?  191 SER B N   1 
ATOM   3158 C CA  . SER B 2 188 ? 141.938 143.417 163.423 1.00 55.11  ?  191 SER B CA  1 
ATOM   3159 C C   . SER B 2 188 ? 141.910 143.059 164.899 1.00 55.11  ?  191 SER B C   1 
ATOM   3160 O O   . SER B 2 188 ? 141.912 143.945 165.757 1.00 55.11  ?  191 SER B O   1 
ATOM   3161 C CB  . SER B 2 188 ? 143.385 143.589 162.949 1.00 55.11  ?  191 SER B CB  1 
ATOM   3162 O OG  . SER B 2 188 ? 144.048 142.340 162.877 1.00 55.11  ?  191 SER B OG  1 
ATOM   3163 N N   . LEU B 2 189 ? 141.881 141.764 165.190 1.00 58.44  ?  192 LEU B N   1 
ATOM   3164 C CA  . LEU B 2 189 ? 141.828 141.271 166.558 1.00 58.44  ?  192 LEU B CA  1 
ATOM   3165 C C   . LEU B 2 189 ? 143.210 140.825 167.012 1.00 58.44  ?  192 LEU B C   1 
ATOM   3166 O O   . LEU B 2 189 ? 143.935 140.157 166.269 1.00 58.44  ?  192 LEU B O   1 
ATOM   3167 C CB  . LEU B 2 189 ? 140.843 140.107 166.682 1.00 58.44  ?  192 LEU B CB  1 
ATOM   3168 C CG  . LEU B 2 189 ? 139.387 140.467 166.966 1.00 58.44  ?  192 LEU B CG  1 
ATOM   3169 C CD1 . LEU B 2 189 ? 138.510 139.241 166.814 1.00 58.44  ?  192 LEU B CD1 1 
ATOM   3170 C CD2 . LEU B 2 189 ? 139.243 141.063 168.355 1.00 58.44  ?  192 LEU B CD2 1 
ATOM   3171 N N   . ALA B 2 190 ? 143.570 141.201 168.235 1.00 63.24  ?  193 ALA B N   1 
ATOM   3172 C CA  . ALA B 2 190 ? 144.842 140.783 168.796 1.00 63.24  ?  193 ALA B CA  1 
ATOM   3173 C C   . ALA B 2 190 ? 144.836 139.277 169.054 1.00 63.24  ?  193 ALA B C   1 
ATOM   3174 O O   . ALA B 2 190 ? 143.776 138.681 169.263 1.00 63.24  ?  193 ALA B O   1 
ATOM   3175 C CB  . ALA B 2 190 ? 145.127 141.534 170.093 1.00 63.24  ?  193 ALA B CB  1 
ATOM   3176 N N   . PRO B 2 191 ? 146.007 138.636 169.025 1.00 68.41  ?  194 PRO B N   1 
ATOM   3177 C CA  . PRO B 2 191 ? 146.050 137.185 169.271 1.00 68.41  ?  194 PRO B CA  1 
ATOM   3178 C C   . PRO B 2 191 ? 145.476 136.774 170.616 1.00 68.41  ?  194 PRO B C   1 
ATOM   3179 O O   . PRO B 2 191 ? 144.862 135.704 170.712 1.00 68.41  ?  194 PRO B O   1 
ATOM   3180 C CB  . PRO B 2 191 ? 147.547 136.863 169.173 1.00 68.41  ?  194 PRO B CB  1 
ATOM   3181 C CG  . PRO B 2 191 ? 148.096 137.924 168.285 1.00 68.41  ?  194 PRO B CG  1 
ATOM   3182 C CD  . PRO B 2 191 ? 147.317 139.165 168.609 1.00 68.41  ?  194 PRO B CD  1 
ATOM   3183 N N   . ASP B 2 192 ? 145.651 137.586 171.659 1.00 72.19  ?  195 ASP B N   1 
ATOM   3184 C CA  . ASP B 2 192 ? 145.074 137.269 172.959 1.00 72.19  ?  195 ASP B CA  1 
ATOM   3185 C C   . ASP B 2 192 ? 143.589 137.596 173.044 1.00 72.19  ?  195 ASP B C   1 
ATOM   3186 O O   . ASP B 2 192 ? 142.957 137.265 174.053 1.00 72.19  ?  195 ASP B O   1 
ATOM   3187 C CB  . ASP B 2 192 ? 145.834 137.998 174.073 1.00 72.19  ?  195 ASP B CB  1 
ATOM   3188 C CG  . ASP B 2 192 ? 145.777 139.509 173.936 1.00 72.19  ?  195 ASP B CG  1 
ATOM   3189 O OD1 . ASP B 2 192 ? 145.218 140.007 172.937 1.00 72.19  ?  195 ASP B OD1 1 
ATOM   3190 O OD2 . ASP B 2 192 ? 146.293 140.203 174.836 1.00 72.19  -1 195 ASP B OD2 1 
ATOM   3191 N N   . THR B 2 193 ? 143.030 138.240 172.016 1.00 70.40  ?  196 THR B N   1 
ATOM   3192 C CA  . THR B 2 193 ? 141.600 138.539 171.934 1.00 70.40  ?  196 THR B CA  1 
ATOM   3193 C C   . THR B 2 193 ? 141.150 139.400 173.117 1.00 70.40  ?  196 THR B C   1 
ATOM   3194 O O   . THR B 2 193 ? 140.079 139.202 173.694 1.00 70.40  ?  196 THR B O   1 
ATOM   3195 C CB  . THR B 2 193 ? 140.778 137.249 171.831 1.00 70.40  ?  196 THR B CB  1 
ATOM   3196 O OG1 . THR B 2 193 ? 141.398 136.375 170.882 1.00 70.40  ?  196 THR B OG1 1 
ATOM   3197 C CG2 . THR B 2 193 ? 139.375 137.541 171.327 1.00 70.40  ?  196 THR B CG2 1 
ATOM   3198 N N   . ARG B 2 194 ? 141.994 140.361 173.498 1.00 73.52  ?  197 ARG B N   1 
ATOM   3199 C CA  . ARG B 2 194 ? 141.650 141.337 174.520 1.00 73.52  ?  197 ARG B CA  1 
ATOM   3200 C C   . ARG B 2 194 ? 141.671 142.773 174.025 1.00 73.52  ?  197 ARG B C   1 
ATOM   3201 O O   . ARG B 2 194 ? 141.049 143.633 174.657 1.00 73.52  ?  197 ARG B O   1 
ATOM   3202 C CB  . ARG B 2 194 ? 142.599 141.217 175.724 1.00 73.52  ?  197 ARG B CB  1 
ATOM   3203 C CG  . ARG B 2 194 ? 142.660 139.826 176.327 1.00 73.52  ?  197 ARG B CG  1 
ATOM   3204 C CD  . ARG B 2 194 ? 141.311 139.409 176.887 1.00 73.52  ?  197 ARG B CD  1 
ATOM   3205 N NE  . ARG B 2 194 ? 141.052 140.002 178.193 1.00 73.52  ?  197 ARG B NE  1 
ATOM   3206 C CZ  . ARG B 2 194 ? 140.050 139.653 178.988 1.00 73.52  ?  197 ARG B CZ  1 
ATOM   3207 N NH1 . ARG B 2 194 ? 139.187 138.712 178.641 1.00 73.52  1  197 ARG B NH1 1 
ATOM   3208 N NH2 . ARG B 2 194 ? 139.910 140.263 180.162 1.00 73.52  ?  197 ARG B NH2 1 
ATOM   3209 N N   . LEU B 2 195 ? 142.362 143.055 172.924 1.00 65.33  ?  198 LEU B N   1 
ATOM   3210 C CA  . LEU B 2 195 ? 142.420 144.381 172.331 1.00 65.33  ?  198 LEU B CA  1 
ATOM   3211 C C   . LEU B 2 195 ? 142.188 144.250 170.834 1.00 65.33  ?  198 LEU B C   1 
ATOM   3212 O O   . LEU B 2 195 ? 142.360 143.175 170.255 1.00 65.33  ?  198 LEU B O   1 
ATOM   3213 C CB  . LEU B 2 195 ? 143.773 145.059 172.590 1.00 65.33  ?  198 LEU B CB  1 
ATOM   3214 C CG  . LEU B 2 195 ? 144.269 145.135 174.034 1.00 65.33  ?  198 LEU B CG  1 
ATOM   3215 C CD1 . LEU B 2 195 ? 145.748 145.478 174.064 1.00 65.33  ?  198 LEU B CD1 1 
ATOM   3216 C CD2 . LEU B 2 195 ? 143.471 146.150 174.827 1.00 65.33  ?  198 LEU B CD2 1 
ATOM   3217 N N   . PHE B 2 196 ? 141.787 145.350 170.203 1.00 59.91  ?  199 PHE B N   1 
ATOM   3218 C CA  . PHE B 2 196 ? 141.647 145.328 168.753 1.00 59.91  ?  199 PHE B CA  1 
ATOM   3219 C C   . PHE B 2 196 ? 141.846 146.724 168.181 1.00 59.91  ?  199 PHE B C   1 
ATOM   3220 O O   . PHE B 2 196 ? 141.456 147.718 168.796 1.00 59.91  ?  199 PHE B O   1 
ATOM   3221 C CB  . PHE B 2 196 ? 140.290 144.743 168.329 1.00 59.91  ?  199 PHE B CB  1 
ATOM   3222 C CG  . PHE B 2 196 ? 139.137 145.697 168.443 1.00 59.91  ?  199 PHE B CG  1 
ATOM   3223 C CD1 . PHE B 2 196 ? 138.478 145.867 169.646 1.00 59.91  ?  199 PHE B CD1 1 
ATOM   3224 C CD2 . PHE B 2 196 ? 138.689 146.399 167.336 1.00 59.91  ?  199 PHE B CD2 1 
ATOM   3225 C CE1 . PHE B 2 196 ? 137.410 146.732 169.750 1.00 59.91  ?  199 PHE B CE1 1 
ATOM   3226 C CE2 . PHE B 2 196 ? 137.623 147.268 167.436 1.00 59.91  ?  199 PHE B CE2 1 
ATOM   3227 C CZ  . PHE B 2 196 ? 136.983 147.434 168.643 1.00 59.91  ?  199 PHE B CZ  1 
ATOM   3228 N N   . VAL B 2 197 ? 142.455 146.786 167.000 1.00 56.00  ?  200 VAL B N   1 
ATOM   3229 C CA  . VAL B 2 197 ? 142.736 148.040 166.312 1.00 56.00  ?  200 VAL B CA  1 
ATOM   3230 C C   . VAL B 2 197 ? 141.740 148.206 165.175 1.00 56.00  ?  200 VAL B C   1 
ATOM   3231 O O   . VAL B 2 197 ? 141.442 147.251 164.449 1.00 56.00  ?  200 VAL B O   1 
ATOM   3232 C CB  . VAL B 2 197 ? 144.181 148.097 165.778 1.00 56.00  ?  200 VAL B CB  1 
ATOM   3233 C CG1 . VAL B 2 197 ? 145.162 148.293 166.913 1.00 56.00  ?  200 VAL B CG1 1 
ATOM   3234 C CG2 . VAL B 2 197 ? 144.513 146.840 164.994 1.00 56.00  ?  200 VAL B CG2 1 
ATOM   3235 N N   . SER B 2 198 ? 141.217 149.419 165.031 1.00 57.42  ?  201 SER B N   1 
ATOM   3236 C CA  . SER B 2 198 ? 140.303 149.757 163.949 1.00 57.42  ?  201 SER B CA  1 
ATOM   3237 C C   . SER B 2 198 ? 140.820 150.992 163.232 1.00 57.42  ?  201 SER B C   1 
ATOM   3238 O O   . SER B 2 198 ? 141.081 152.016 163.870 1.00 57.42  ?  201 SER B O   1 
ATOM   3239 C CB  . SER B 2 198 ? 138.886 150.003 164.475 1.00 57.42  ?  201 SER B CB  1 
ATOM   3240 O OG  . SER B 2 198 ? 138.853 151.126 165.338 1.00 57.42  ?  201 SER B OG  1 
ATOM   3241 N N   . GLY B 2 199 ? 140.970 150.895 161.916 1.00 57.93  ?  202 GLY B N   1 
ATOM   3242 C CA  . GLY B 2 199 ? 141.402 152.016 161.097 1.00 57.93  ?  202 GLY B CA  1 
ATOM   3243 C C   . GLY B 2 199 ? 140.214 152.653 160.399 1.00 57.93  ?  202 GLY B C   1 
ATOM   3244 O O   . GLY B 2 199 ? 139.332 151.957 159.891 1.00 57.93  ?  202 GLY B O   1 
ATOM   3245 N N   . ALA B 2 200 ? 140.196 153.981 160.376 1.00 60.53  ?  203 ALA B N   1 
ATOM   3246 C CA  . ALA B 2 200 ? 139.047 154.697 159.842 1.00 60.53  ?  203 ALA B CA  1 
ATOM   3247 C C   . ALA B 2 200 ? 139.475 155.640 158.723 1.00 60.53  ?  203 ALA B C   1 
ATOM   3248 O O   . ALA B 2 200 ? 140.650 155.728 158.361 1.00 60.53  ?  203 ALA B O   1 
ATOM   3249 C CB  . ALA B 2 200 ? 138.318 155.460 160.948 1.00 60.53  ?  203 ALA B CB  1 
ATOM   3250 N N   . CYS B 2 201 ? 138.490 156.350 158.174 1.00 66.23  ?  204 CYS B N   1 
ATOM   3251 C CA  . CYS B 2 201 ? 138.713 157.281 157.077 1.00 66.23  ?  204 CYS B CA  1 
ATOM   3252 C C   . CYS B 2 201 ? 139.269 158.620 157.538 1.00 66.23  ?  204 CYS B C   1 
ATOM   3253 O O   . CYS B 2 201 ? 139.602 159.457 156.693 1.00 66.23  ?  204 CYS B O   1 
ATOM   3254 C CB  . CYS B 2 201 ? 137.411 157.506 156.305 1.00 66.23  ?  204 CYS B CB  1 
ATOM   3255 S SG  . CYS B 2 201 ? 136.986 156.175 155.163 1.00 66.23  ?  204 CYS B SG  1 
ATOM   3256 N N   . ASP B 2 202 ? 139.375 158.846 158.846 1.00 67.19  ?  205 ASP B N   1 
ATOM   3257 C CA  . ASP B 2 202 ? 140.001 160.049 159.374 1.00 67.19  ?  205 ASP B CA  1 
ATOM   3258 C C   . ASP B 2 202 ? 141.516 159.934 159.451 1.00 67.19  ?  205 ASP B C   1 
ATOM   3259 O O   . ASP B 2 202 ? 142.146 160.696 160.195 1.00 67.19  ?  205 ASP B O   1 
ATOM   3260 C CB  . ASP B 2 202 ? 139.428 160.381 160.754 1.00 67.19  ?  205 ASP B CB  1 
ATOM   3261 C CG  . ASP B 2 202 ? 139.569 159.236 161.734 1.00 67.19  ?  205 ASP B CG  1 
ATOM   3262 O OD1 . ASP B 2 202 ? 139.979 158.137 161.312 1.00 67.19  ?  205 ASP B OD1 1 
ATOM   3263 O OD2 . ASP B 2 202 ? 139.271 159.435 162.930 1.00 67.19  -1 205 ASP B OD2 1 
ATOM   3264 N N   . ALA B 2 203 ? 142.098 158.995 158.701 1.00 65.25  ?  206 ALA B N   1 
ATOM   3265 C CA  . ALA B 2 203 ? 143.542 158.762 158.688 1.00 65.25  ?  206 ALA B CA  1 
ATOM   3266 C C   . ALA B 2 203 ? 144.070 158.454 160.086 1.00 65.25  ?  206 ALA B C   1 
ATOM   3267 O O   . ALA B 2 203 ? 145.119 158.952 160.497 1.00 65.25  ?  206 ALA B O   1 
ATOM   3268 C CB  . ALA B 2 203 ? 144.289 159.947 158.073 1.00 65.25  ?  206 ALA B CB  1 
ATOM   3269 N N   . SER B 2 204 ? 143.337 157.626 160.827 1.00 63.18  ?  207 SER B N   1 
ATOM   3270 C CA  . SER B 2 204 ? 143.754 157.255 162.169 1.00 63.18  ?  207 SER B CA  1 
ATOM   3271 C C   . SER B 2 204 ? 143.325 155.827 162.468 1.00 63.18  ?  207 SER B C   1 
ATOM   3272 O O   . SER B 2 204 ? 142.299 155.346 161.971 1.00 63.18  ?  207 SER B O   1 
ATOM   3273 C CB  . SER B 2 204 ? 143.178 158.207 163.223 1.00 63.18  ?  207 SER B CB  1 
ATOM   3274 O OG  . SER B 2 204 ? 141.800 157.961 163.433 1.00 63.18  ?  207 SER B OG  1 
ATOM   3275 N N   . ALA B 2 205 ? 144.121 155.163 163.304 1.00 61.41  ?  208 ALA B N   1 
ATOM   3276 C CA  . ALA B 2 205 ? 143.835 153.816 163.777 1.00 61.41  ?  208 ALA B CA  1 
ATOM   3277 C C   . ALA B 2 205 ? 143.793 153.830 165.297 1.00 61.41  ?  208 ALA B C   1 
ATOM   3278 O O   . ALA B 2 205 ? 144.730 154.305 165.943 1.00 61.41  ?  208 ALA B O   1 
ATOM   3279 C CB  . ALA B 2 205 ? 144.885 152.821 163.281 1.00 61.41  ?  208 ALA B CB  1 
ATOM   3280 N N   . LYS B 2 206 ? 142.718 153.302 165.866 1.00 62.44  ?  209 LYS B N   1 
ATOM   3281 C CA  . LYS B 2 206 ? 142.504 153.342 167.305 1.00 62.44  ?  209 LYS B CA  1 
ATOM   3282 C C   . LYS B 2 206 ? 142.582 151.939 167.888 1.00 62.44  ?  209 LYS B C   1 
ATOM   3283 O O   . LYS B 2 206 ? 141.986 151.001 167.348 1.00 62.44  ?  209 LYS B O   1 
ATOM   3284 C CB  . LYS B 2 206 ? 141.157 153.985 167.637 1.00 62.44  ?  209 LYS B CB  1 
ATOM   3285 C CG  . LYS B 2 206 ? 141.101 155.471 167.329 1.00 62.44  ?  209 LYS B CG  1 
ATOM   3286 C CD  . LYS B 2 206 ? 139.745 156.061 167.665 1.00 62.44  ?  209 LYS B CD  1 
ATOM   3287 C CE  . LYS B 2 206 ? 139.789 157.578 167.663 1.00 62.44  ?  209 LYS B CE  1 
ATOM   3288 N NZ  . LYS B 2 206 ? 140.764 158.103 168.657 1.00 62.44  1  209 LYS B NZ  1 
ATOM   3289 N N   . LEU B 2 207 ? 143.327 151.808 168.982 1.00 64.94  ?  210 LEU B N   1 
ATOM   3290 C CA  . LEU B 2 207 ? 143.396 150.589 169.776 1.00 64.94  ?  210 LEU B CA  1 
ATOM   3291 C C   . LEU B 2 207 ? 142.350 150.665 170.878 1.00 64.94  ?  210 LEU B C   1 
ATOM   3292 O O   . LEU B 2 207 ? 142.430 151.541 171.750 1.00 64.94  ?  210 LEU B O   1 
ATOM   3293 C CB  . LEU B 2 207 ? 144.786 150.410 170.385 1.00 64.94  ?  210 LEU B CB  1 
ATOM   3294 C CG  . LEU B 2 207 ? 145.008 149.153 171.231 1.00 64.94  ?  210 LEU B CG  1 
ATOM   3295 C CD1 . LEU B 2 207 ? 144.864 147.883 170.413 1.00 64.94  ?  210 LEU B CD1 1 
ATOM   3296 C CD2 . LEU B 2 207 ? 146.357 149.202 171.930 1.00 64.94  ?  210 LEU B CD2 1 
ATOM   3297 N N   . TRP B 2 208 ? 141.386 149.748 170.837 1.00 63.80  ?  211 TRP B N   1 
ATOM   3298 C CA  . TRP B 2 208 ? 140.314 149.643 171.811 1.00 63.80  ?  211 TRP B CA  1 
ATOM   3299 C C   . TRP B 2 208 ? 140.516 148.405 172.673 1.00 63.80  ?  211 TRP B C   1 
ATOM   3300 O O   . TRP B 2 208 ? 141.043 147.385 172.215 1.00 63.80  ?  211 TRP B O   1 
ATOM   3301 C CB  . TRP B 2 208 ? 138.946 149.538 171.132 1.00 63.80  ?  211 TRP B CB  1 
ATOM   3302 C CG  . TRP B 2 208 ? 138.758 150.400 169.932 1.00 63.80  ?  211 TRP B CG  1 
ATOM   3303 C CD1 . TRP B 2 208 ? 139.144 150.122 168.655 1.00 63.80  ?  211 TRP B CD1 1 
ATOM   3304 C CD2 . TRP B 2 208 ? 138.094 151.665 169.884 1.00 63.80  ?  211 TRP B CD2 1 
ATOM   3305 N NE1 . TRP B 2 208 ? 138.781 151.145 167.817 1.00 63.80  ?  211 TRP B NE1 1 
ATOM   3306 C CE2 . TRP B 2 208 ? 138.133 152.106 168.548 1.00 63.80  ?  211 TRP B CE2 1 
ATOM   3307 C CE3 . TRP B 2 208 ? 137.480 152.473 170.843 1.00 63.80  ?  211 TRP B CE3 1 
ATOM   3308 C CZ2 . TRP B 2 208 ? 137.581 153.317 168.147 1.00 63.80  ?  211 TRP B CZ2 1 
ATOM   3309 C CZ3 . TRP B 2 208 ? 136.933 153.673 170.444 1.00 63.80  ?  211 TRP B CZ3 1 
ATOM   3310 C CH2 . TRP B 2 208 ? 136.987 154.085 169.108 1.00 63.80  ?  211 TRP B CH2 1 
ATOM   3311 N N   . ASP B 2 209 ? 140.069 148.504 173.922 1.00 74.37  ?  212 ASP B N   1 
ATOM   3312 C CA  . ASP B 2 209 ? 140.035 147.378 174.845 1.00 74.37  ?  212 ASP B CA  1 
ATOM   3313 C C   . ASP B 2 209 ? 138.636 146.777 174.800 1.00 74.37  ?  212 ASP B C   1 
ATOM   3314 O O   . ASP B 2 209 ? 137.647 147.480 175.032 1.00 74.37  ?  212 ASP B O   1 
ATOM   3315 C CB  . ASP B 2 209 ? 140.400 147.826 176.261 1.00 74.37  ?  212 ASP B CB  1 
ATOM   3316 C CG  . ASP B 2 209 ? 140.557 146.663 177.230 1.00 74.37  ?  212 ASP B CG  1 
ATOM   3317 O OD1 . ASP B 2 209 ? 139.717 145.739 177.225 1.00 74.37  ?  212 ASP B OD1 1 
ATOM   3318 O OD2 . ASP B 2 209 ? 141.533 146.676 178.009 1.00 74.37  -1 212 ASP B OD2 1 
ATOM   3319 N N   . VAL B 2 210 ? 138.556 145.479 174.499 1.00 70.65  ?  213 VAL B N   1 
ATOM   3320 C CA  . VAL B 2 210 ? 137.259 144.831 174.333 1.00 70.65  ?  213 VAL B CA  1 
ATOM   3321 C C   . VAL B 2 210 ? 136.505 144.753 175.655 1.00 70.65  ?  213 VAL B C   1 
ATOM   3322 O O   . VAL B 2 210 ? 135.274 144.873 175.680 1.00 70.65  ?  213 VAL B O   1 
ATOM   3323 C CB  . VAL B 2 210 ? 137.443 143.437 173.706 1.00 70.65  ?  213 VAL B CB  1 
ATOM   3324 C CG1 . VAL B 2 210 ? 136.096 142.823 173.367 1.00 70.65  ?  213 VAL B CG1 1 
ATOM   3325 C CG2 . VAL B 2 210 ? 138.316 143.527 172.468 1.00 70.65  ?  213 VAL B CG2 1 
ATOM   3326 N N   . ARG B 2 211 ? 137.215 144.553 176.765 1.00 78.00  ?  214 ARG B N   1 
ATOM   3327 C CA  . ARG B 2 211 ? 136.581 144.330 178.060 1.00 78.00  ?  214 ARG B CA  1 
ATOM   3328 C C   . ARG B 2 211 ? 135.718 145.509 178.496 1.00 78.00  ?  214 ARG B C   1 
ATOM   3329 O O   . ARG B 2 211 ? 134.500 145.369 178.638 1.00 78.00  ?  214 ARG B O   1 
ATOM   3330 C CB  . ARG B 2 211 ? 137.642 144.039 179.124 1.00 78.00  ?  214 ARG B CB  1 
ATOM   3331 N N   . GLU B 2 212 ? 136.334 146.673 178.709 1.00 83.19  ?  215 GLU B N   1 
ATOM   3332 C CA  . GLU B 2 212 ? 135.579 147.825 179.191 1.00 83.19  ?  215 GLU B CA  1 
ATOM   3333 C C   . GLU B 2 212 ? 135.013 148.667 178.054 1.00 83.19  ?  215 GLU B C   1 
ATOM   3334 O O   . GLU B 2 212 ? 133.998 149.346 178.241 1.00 83.19  ?  215 GLU B O   1 
ATOM   3335 C CB  . GLU B 2 212 ? 136.453 148.686 180.106 1.00 83.19  ?  215 GLU B CB  1 
ATOM   3336 C CG  . GLU B 2 212 ? 137.679 149.276 179.437 1.00 83.19  ?  215 GLU B CG  1 
ATOM   3337 C CD  . GLU B 2 212 ? 138.888 148.371 179.552 1.00 83.19  ?  215 GLU B CD  1 
ATOM   3338 O OE1 . GLU B 2 212 ? 138.710 147.176 179.870 1.00 83.19  ?  215 GLU B OE1 1 
ATOM   3339 O OE2 . GLU B 2 212 ? 140.018 148.852 179.330 1.00 83.19  -1 215 GLU B OE2 1 
ATOM   3340 N N   . GLY B 2 213 ? 135.643 148.643 176.883 1.00 81.85  ?  216 GLY B N   1 
ATOM   3341 C CA  . GLY B 2 213 ? 135.096 149.330 175.731 1.00 81.85  ?  216 GLY B CA  1 
ATOM   3342 C C   . GLY B 2 213 ? 135.472 150.794 175.632 1.00 81.85  ?  216 GLY B C   1 
ATOM   3343 O O   . GLY B 2 213 ? 134.601 151.651 175.454 1.00 81.85  ?  216 GLY B O   1 
ATOM   3344 N N   . MET B 2 214 ? 136.762 151.095 175.742 1.00 84.72  ?  217 MET B N   1 
ATOM   3345 C CA  . MET B 2 214 ? 137.255 152.459 175.633 1.00 84.72  ?  217 MET B CA  1 
ATOM   3346 C C   . MET B 2 214 ? 138.452 152.495 174.696 1.00 84.72  ?  217 MET B C   1 
ATOM   3347 O O   . MET B 2 214 ? 139.154 151.496 174.520 1.00 84.72  ?  217 MET B O   1 
ATOM   3348 C CB  . MET B 2 214 ? 137.640 153.028 177.005 1.00 84.72  ?  217 MET B CB  1 
ATOM   3349 C CG  . MET B 2 214 ? 138.816 152.330 177.664 1.00 84.72  ?  217 MET B CG  1 
ATOM   3350 S SD  . MET B 2 214 ? 139.181 153.013 179.291 1.00 84.72  ?  217 MET B SD  1 
ATOM   3351 C CE  . MET B 2 214 ? 140.564 151.992 179.791 1.00 84.72  ?  217 MET B CE  1 
ATOM   3352 N N   . CYS B 2 215 ? 138.677 153.659 174.092 1.00 81.51  ?  218 CYS B N   1 
ATOM   3353 C CA  . CYS B 2 215 ? 139.787 153.843 173.160 1.00 81.51  ?  218 CYS B CA  1 
ATOM   3354 C C   . CYS B 2 215 ? 141.085 153.912 173.951 1.00 81.51  ?  218 CYS B C   1 
ATOM   3355 O O   . CYS B 2 215 ? 141.429 154.951 174.517 1.00 81.51  ?  218 CYS B O   1 
ATOM   3356 C CB  . CYS B 2 215 ? 139.582 155.102 172.327 1.00 81.51  ?  218 CYS B CB  1 
ATOM   3357 S SG  . CYS B 2 215 ? 140.863 155.391 171.087 1.00 81.51  ?  218 CYS B SG  1 
ATOM   3358 N N   . ARG B 2 216 ? 141.809 152.792 174.000 1.00 79.06  ?  219 ARG B N   1 
ATOM   3359 C CA  . ARG B 2 216 ? 143.062 152.757 174.744 1.00 79.06  ?  219 ARG B CA  1 
ATOM   3360 C C   . ARG B 2 216 ? 144.107 153.674 174.123 1.00 79.06  ?  219 ARG B C   1 
ATOM   3361 O O   . ARG B 2 216 ? 144.800 154.406 174.839 1.00 79.06  ?  219 ARG B O   1 
ATOM   3362 C CB  . ARG B 2 216 ? 143.586 151.323 174.823 1.00 79.06  ?  219 ARG B CB  1 
ATOM   3363 C CG  . ARG B 2 216 ? 144.921 151.191 175.534 1.00 79.06  ?  219 ARG B CG  1 
ATOM   3364 C CD  . ARG B 2 216 ? 144.917 150.029 176.512 1.00 79.06  ?  219 ARG B CD  1 
ATOM   3365 N NE  . ARG B 2 216 ? 143.777 150.078 177.418 1.00 79.06  ?  219 ARG B NE  1 
ATOM   3366 C CZ  . ARG B 2 216 ? 143.456 149.114 178.270 1.00 79.06  ?  219 ARG B CZ  1 
ATOM   3367 N NH1 . ARG B 2 216 ? 144.171 148.004 178.358 1.00 79.06  1  219 ARG B NH1 1 
ATOM   3368 N NH2 . ARG B 2 216 ? 142.392 149.266 179.053 1.00 79.06  ?  219 ARG B NH2 1 
ATOM   3369 N N   . GLN B 2 217 ? 144.231 153.660 172.796 1.00 75.82  ?  220 GLN B N   1 
ATOM   3370 C CA  . GLN B 2 217 ? 145.281 154.436 172.146 1.00 75.82  ?  220 GLN B CA  1 
ATOM   3371 C C   . GLN B 2 217 ? 144.817 154.903 170.774 1.00 75.82  ?  220 GLN B C   1 
ATOM   3372 O O   . GLN B 2 217 ? 143.892 154.341 170.186 1.00 75.82  ?  220 GLN B O   1 
ATOM   3373 C CB  . GLN B 2 217 ? 146.579 153.628 172.013 1.00 75.82  ?  220 GLN B CB  1 
ATOM   3374 C CG  . GLN B 2 217 ? 147.463 153.661 173.248 1.00 75.82  ?  220 GLN B CG  1 
ATOM   3375 C CD  . GLN B 2 217 ? 148.567 152.625 173.203 1.00 75.82  ?  220 GLN B CD  1 
ATOM   3376 O OE1 . GLN B 2 217 ? 148.526 151.626 173.919 1.00 75.82  ?  220 GLN B OE1 1 
ATOM   3377 N NE2 . GLN B 2 217 ? 149.565 152.860 172.361 1.00 75.82  ?  220 GLN B NE2 1 
ATOM   3378 N N   . THR B 2 218 ? 145.484 155.938 170.266 1.00 73.29  ?  221 THR B N   1 
ATOM   3379 C CA  . THR B 2 218 ? 145.215 156.481 168.941 1.00 73.29  ?  221 THR B CA  1 
ATOM   3380 C C   . THR B 2 218 ? 146.528 156.682 168.199 1.00 73.29  ?  221 THR B C   1 
ATOM   3381 O O   . THR B 2 218 ? 147.497 157.195 168.765 1.00 73.29  ?  221 THR B O   1 
ATOM   3382 C CB  . THR B 2 218 ? 144.454 157.812 169.025 1.00 73.29  ?  221 THR B CB  1 
ATOM   3383 O OG1 . THR B 2 218 ? 143.280 157.643 169.828 1.00 73.29  ?  221 THR B OG1 1 
ATOM   3384 C CG2 . THR B 2 218 ? 144.047 158.283 167.639 1.00 73.29  ?  221 THR B CG2 1 
ATOM   3385 N N   . PHE B 2 219 ? 146.556 156.280 166.928 1.00 67.77  ?  222 PHE B N   1 
ATOM   3386 C CA  . PHE B 2 219 ? 147.745 156.368 166.095 1.00 67.77  ?  222 PHE B CA  1 
ATOM   3387 C C   . PHE B 2 219 ? 147.404 157.118 164.818 1.00 67.77  ?  222 PHE B C   1 
ATOM   3388 O O   . PHE B 2 219 ? 146.418 156.793 164.146 1.00 67.77  ?  222 PHE B O   1 
ATOM   3389 C CB  . PHE B 2 219 ? 148.288 154.977 165.754 1.00 67.77  ?  222 PHE B CB  1 
ATOM   3390 C CG  . PHE B 2 219 ? 148.571 154.124 166.954 1.00 67.77  ?  222 PHE B CG  1 
ATOM   3391 C CD1 . PHE B 2 219 ? 147.592 153.299 167.479 1.00 67.77  ?  222 PHE B CD1 1 
ATOM   3392 C CD2 . PHE B 2 219 ? 149.816 154.141 167.555 1.00 67.77  ?  222 PHE B CD2 1 
ATOM   3393 C CE1 . PHE B 2 219 ? 147.849 152.513 168.581 1.00 67.77  ?  222 PHE B CE1 1 
ATOM   3394 C CE2 . PHE B 2 219 ? 150.078 153.357 168.657 1.00 67.77  ?  222 PHE B CE2 1 
ATOM   3395 C CZ  . PHE B 2 219 ? 149.093 152.541 169.170 1.00 67.77  ?  222 PHE B CZ  1 
ATOM   3396 N N   . THR B 2 220 ? 148.224 158.110 164.487 1.00 68.58  ?  223 THR B N   1 
ATOM   3397 C CA  . THR B 2 220 ? 148.074 158.910 163.283 1.00 68.58  ?  223 THR B CA  1 
ATOM   3398 C C   . THR B 2 220 ? 149.355 158.843 162.462 1.00 68.58  ?  223 THR B C   1 
ATOM   3399 O O   . THR B 2 220 ? 150.351 158.236 162.864 1.00 68.58  ?  223 THR B O   1 
ATOM   3400 C CB  . THR B 2 220 ? 147.740 160.368 163.623 1.00 68.58  ?  223 THR B CB  1 
ATOM   3401 O OG1 . THR B 2 220 ? 148.747 160.899 164.494 1.00 68.58  ?  223 THR B OG1 1 
ATOM   3402 C CG2 . THR B 2 220 ? 146.387 160.459 164.308 1.00 68.58  ?  223 THR B CG2 1 
ATOM   3403 N N   . GLY B 2 221 ? 149.321 159.483 161.297 1.00 67.28  ?  224 GLY B N   1 
ATOM   3404 C CA  . GLY B 2 221 ? 150.470 159.504 160.415 1.00 67.28  ?  224 GLY B CA  1 
ATOM   3405 C C   . GLY B 2 221 ? 150.094 159.331 158.959 1.00 67.28  ?  224 GLY B C   1 
ATOM   3406 O O   . GLY B 2 221 ? 150.771 159.853 158.069 1.00 67.28  ?  224 GLY B O   1 
ATOM   3407 N N   . HIS B 2 222 ? 149.015 158.598 158.706 1.00 63.95  ?  225 HIS B N   1 
ATOM   3408 C CA  . HIS B 2 222 ? 148.517 158.449 157.349 1.00 63.95  ?  225 HIS B CA  1 
ATOM   3409 C C   . HIS B 2 222 ? 147.936 159.766 156.850 1.00 63.95  ?  225 HIS B C   1 
ATOM   3410 O O   . HIS B 2 222 ? 147.418 160.576 157.623 1.00 63.95  ?  225 HIS B O   1 
ATOM   3411 C CB  . HIS B 2 222 ? 147.454 157.353 157.287 1.00 63.95  ?  225 HIS B CB  1 
ATOM   3412 C CG  . HIS B 2 222 ? 148.015 155.972 157.158 1.00 63.95  ?  225 HIS B CG  1 
ATOM   3413 N ND1 . HIS B 2 222 ? 148.636 155.524 156.012 1.00 63.95  ?  225 HIS B ND1 1 
ATOM   3414 C CD2 . HIS B 2 222 ? 148.048 154.939 158.032 1.00 63.95  ?  225 HIS B CD2 1 
ATOM   3415 C CE1 . HIS B 2 222 ? 149.021 154.272 156.184 1.00 63.95  ?  225 HIS B CE1 1 
ATOM   3416 N NE2 . HIS B 2 222 ? 148.680 153.895 157.402 1.00 63.95  ?  225 HIS B NE2 1 
ATOM   3417 N N   . GLU B 2 223 ? 148.037 159.983 155.542 1.00 71.50  ?  226 GLU B N   1 
ATOM   3418 C CA  . GLU B 2 223 ? 147.520 161.190 154.915 1.00 71.50  ?  226 GLU B CA  1 
ATOM   3419 C C   . GLU B 2 223 ? 146.210 160.965 154.173 1.00 71.50  ?  226 GLU B C   1 
ATOM   3420 O O   . GLU B 2 223 ? 145.739 161.878 153.489 1.00 71.50  ?  226 GLU B O   1 
ATOM   3421 C CB  . GLU B 2 223 ? 148.561 161.774 153.956 1.00 71.50  ?  226 GLU B CB  1 
ATOM   3422 C CG  . GLU B 2 223 ? 149.960 161.860 154.539 1.00 71.50  ?  226 GLU B CG  1 
ATOM   3423 C CD  . GLU B 2 223 ? 151.036 161.838 153.474 1.00 71.50  ?  226 GLU B CD  1 
ATOM   3424 O OE1 . GLU B 2 223 ? 150.688 161.825 152.275 1.00 71.50  ?  226 GLU B OE1 1 
ATOM   3425 O OE2 . GLU B 2 223 ? 152.232 161.834 153.835 1.00 71.50  -1 226 GLU B OE2 1 
ATOM   3426 N N   . SER B 2 224 ? 145.610 159.785 154.289 1.00 68.26  ?  227 SER B N   1 
ATOM   3427 C CA  . SER B 2 224 ? 144.371 159.484 153.584 1.00 68.26  ?  227 SER B CA  1 
ATOM   3428 C C   . SER B 2 224 ? 143.622 158.407 154.361 1.00 68.26  ?  227 SER B C   1 
ATOM   3429 O O   . SER B 2 224 ? 144.018 158.025 155.467 1.00 68.26  ?  227 SER B O   1 
ATOM   3430 C CB  . SER B 2 224 ? 144.654 159.061 152.139 1.00 68.26  ?  227 SER B CB  1 
ATOM   3431 O OG  . SER B 2 224 ? 143.497 159.197 151.334 1.00 68.26  ?  227 SER B OG  1 
ATOM   3432 N N   . ASP B 2 225 ? 142.533 157.914 153.775 1.00 67.42  ?  228 ASP B N   1 
ATOM   3433 C CA  . ASP B 2 225 ? 141.693 156.927 154.438 1.00 67.42  ?  228 ASP B CA  1 
ATOM   3434 C C   . ASP B 2 225 ? 142.442 155.612 154.609 1.00 67.42  ?  228 ASP B C   1 
ATOM   3435 O O   . ASP B 2 225 ? 143.120 155.148 153.688 1.00 67.42  ?  228 ASP B O   1 
ATOM   3436 C CB  . ASP B 2 225 ? 140.414 156.701 153.635 1.00 67.42  ?  228 ASP B CB  1 
ATOM   3437 C CG  . ASP B 2 225 ? 139.731 157.997 153.252 1.00 67.42  ?  228 ASP B CG  1 
ATOM   3438 O OD1 . ASP B 2 225 ? 140.048 159.040 153.861 1.00 67.42  ?  228 ASP B OD1 1 
ATOM   3439 O OD2 . ASP B 2 225 ? 138.878 157.975 152.340 1.00 67.42  -1 228 ASP B OD2 1 
ATOM   3440 N N   . ILE B 2 226 ? 142.310 155.007 155.785 1.00 58.92  ?  229 ILE B N   1 
ATOM   3441 C CA  . ILE B 2 226 ? 142.914 153.711 156.072 1.00 58.92  ?  229 ILE B CA  1 
ATOM   3442 C C   . ILE B 2 226 ? 141.918 152.628 155.680 1.00 58.92  ?  229 ILE B C   1 
ATOM   3443 O O   . ILE B 2 226 ? 140.808 152.573 156.217 1.00 58.92  ?  229 ILE B O   1 
ATOM   3444 C CB  . ILE B 2 226 ? 143.298 153.592 157.554 1.00 58.92  ?  229 ILE B CB  1 
ATOM   3445 C CG1 . ILE B 2 226 ? 144.421 154.567 157.900 1.00 58.92  ?  229 ILE B CG1 1 
ATOM   3446 C CG2 . ILE B 2 226 ? 143.712 152.169 157.881 1.00 58.92  ?  229 ILE B CG2 1 
ATOM   3447 C CD1 . ILE B 2 226 ? 144.895 154.454 159.329 1.00 58.92  ?  229 ILE B CD1 1 
ATOM   3448 N N   . ASN B 2 227 ? 142.315 151.762 154.748 1.00 60.11  ?  230 ASN B N   1 
ATOM   3449 C CA  . ASN B 2 227 ? 141.425 150.731 154.236 1.00 60.11  ?  230 ASN B CA  1 
ATOM   3450 C C   . ASN B 2 227 ? 141.642 149.364 154.869 1.00 60.11  ?  230 ASN B C   1 
ATOM   3451 O O   . ASN B 2 227 ? 140.739 148.524 154.808 1.00 60.11  ?  230 ASN B O   1 
ATOM   3452 C CB  . ASN B 2 227 ? 141.584 150.599 152.717 1.00 60.11  ?  230 ASN B CB  1 
ATOM   3453 C CG  . ASN B 2 227 ? 141.332 151.901 151.990 1.00 60.11  ?  230 ASN B CG  1 
ATOM   3454 O OD1 . ASN B 2 227 ? 140.412 152.645 152.325 1.00 60.11  ?  230 ASN B OD1 1 
ATOM   3455 N ND2 . ASN B 2 227 ? 142.152 152.185 150.986 1.00 60.11  ?  230 ASN B ND2 1 
ATOM   3456 N N   . ALA B 2 228 ? 142.805 149.117 155.468 1.00 54.82  ?  231 ALA B N   1 
ATOM   3457 C CA  . ALA B 2 228 ? 143.106 147.802 156.013 1.00 54.82  ?  231 ALA B CA  1 
ATOM   3458 C C   . ALA B 2 228 ? 143.975 147.946 157.251 1.00 54.82  ?  231 ALA B C   1 
ATOM   3459 O O   . ALA B 2 228 ? 144.654 148.957 157.447 1.00 54.82  ?  231 ALA B O   1 
ATOM   3460 C CB  . ALA B 2 228 ? 143.801 146.913 154.980 1.00 54.82  ?  231 ALA B CB  1 
ATOM   3461 N N   . ILE B 2 229 ? 143.946 146.910 158.089 1.00 53.46  ?  232 ILE B N   1 
ATOM   3462 C CA  . ILE B 2 229 ? 144.733 146.882 159.314 1.00 53.46  ?  232 ILE B CA  1 
ATOM   3463 C C   . ILE B 2 229 ? 144.951 145.425 159.694 1.00 53.46  ?  232 ILE B C   1 
ATOM   3464 O O   . ILE B 2 229 ? 144.142 144.555 159.361 1.00 53.46  ?  232 ILE B O   1 
ATOM   3465 C CB  . ILE B 2 229 ? 144.039 147.686 160.443 1.00 53.46  ?  232 ILE B CB  1 
ATOM   3466 C CG1 . ILE B 2 229 ? 145.056 148.131 161.491 1.00 53.46  ?  232 ILE B CG1 1 
ATOM   3467 C CG2 . ILE B 2 229 ? 142.932 146.875 161.085 1.00 53.46  ?  232 ILE B CG2 1 
ATOM   3468 C CD1 . ILE B 2 229 ? 144.582 149.289 162.327 1.00 53.46  ?  232 ILE B CD1 1 
ATOM   3469 N N   . CYS B 2 230 ? 146.063 145.157 160.378 1.00 56.11  ?  233 CYS B N   1 
ATOM   3470 C CA  . CYS B 2 230 ? 146.403 143.794 160.773 1.00 56.11  ?  233 CYS B CA  1 
ATOM   3471 C C   . CYS B 2 230 ? 147.427 143.838 161.895 1.00 56.11  ?  233 CYS B C   1 
ATOM   3472 O O   . CYS B 2 230 ? 148.403 144.588 161.813 1.00 56.11  ?  233 CYS B O   1 
ATOM   3473 C CB  . CYS B 2 230 ? 146.953 143.000 159.584 1.00 56.11  ?  233 CYS B CB  1 
ATOM   3474 S SG  . CYS B 2 230 ? 146.889 141.206 159.788 1.00 56.11  ?  233 CYS B SG  1 
ATOM   3475 N N   . PHE B 2 231 ? 147.206 143.034 162.933 1.00 56.11  ?  234 PHE B N   1 
ATOM   3476 C CA  . PHE B 2 231 ? 148.172 142.923 164.017 1.00 56.11  ?  234 PHE B CA  1 
ATOM   3477 C C   . PHE B 2 231 ? 149.423 142.169 163.585 1.00 56.11  ?  234 PHE B C   1 
ATOM   3478 O O   . PHE B 2 231 ? 149.382 141.274 162.738 1.00 56.11  ?  234 PHE B O   1 
ATOM   3479 C CB  . PHE B 2 231 ? 147.568 142.213 165.228 1.00 56.11  ?  234 PHE B CB  1 
ATOM   3480 C CG  . PHE B 2 231 ? 146.805 143.113 166.149 1.00 56.11  ?  234 PHE B CG  1 
ATOM   3481 C CD1 . PHE B 2 231 ? 147.472 143.853 167.110 1.00 56.11  ?  234 PHE B CD1 1 
ATOM   3482 C CD2 . PHE B 2 231 ? 145.429 143.195 166.085 1.00 56.11  ?  234 PHE B CD2 1 
ATOM   3483 C CE1 . PHE B 2 231 ? 146.783 144.675 167.973 1.00 56.11  ?  234 PHE B CE1 1 
ATOM   3484 C CE2 . PHE B 2 231 ? 144.735 144.014 166.950 1.00 56.11  ?  234 PHE B CE2 1 
ATOM   3485 C CZ  . PHE B 2 231 ? 145.413 144.756 167.893 1.00 56.11  ?  234 PHE B CZ  1 
ATOM   3486 N N   . PHE B 2 232 ? 150.544 142.550 164.187 1.00 63.24  ?  235 PHE B N   1 
ATOM   3487 C CA  . PHE B 2 232 ? 151.738 141.729 164.142 1.00 63.24  ?  235 PHE B CA  1 
ATOM   3488 C C   . PHE B 2 232 ? 151.471 140.418 164.881 1.00 63.24  ?  235 PHE B C   1 
ATOM   3489 O O   . PHE B 2 232 ? 150.682 140.387 165.831 1.00 63.24  ?  235 PHE B O   1 
ATOM   3490 C CB  . PHE B 2 232 ? 152.908 142.472 164.784 1.00 63.24  ?  235 PHE B CB  1 
ATOM   3491 C CG  . PHE B 2 232 ? 154.256 141.958 164.382 1.00 63.24  ?  235 PHE B CG  1 
ATOM   3492 C CD1 . PHE B 2 232 ? 154.749 142.191 163.112 1.00 63.24  ?  235 PHE B CD1 1 
ATOM   3493 C CD2 . PHE B 2 232 ? 155.034 141.250 165.279 1.00 63.24  ?  235 PHE B CD2 1 
ATOM   3494 C CE1 . PHE B 2 232 ? 155.990 141.722 162.743 1.00 63.24  ?  235 PHE B CE1 1 
ATOM   3495 C CE2 . PHE B 2 232 ? 156.275 140.778 164.915 1.00 63.24  ?  235 PHE B CE2 1 
ATOM   3496 C CZ  . PHE B 2 232 ? 156.754 141.015 163.646 1.00 63.24  ?  235 PHE B CZ  1 
ATOM   3497 N N   . PRO B 2 233 ? 152.096 139.316 164.459 1.00 64.86  ?  236 PRO B N   1 
ATOM   3498 C CA  . PRO B 2 233 ? 151.882 138.045 165.172 1.00 64.86  ?  236 PRO B CA  1 
ATOM   3499 C C   . PRO B 2 233 ? 152.235 138.112 166.646 1.00 64.86  ?  236 PRO B C   1 
ATOM   3500 O O   . PRO B 2 233 ? 151.634 137.391 167.451 1.00 64.86  ?  236 PRO B O   1 
ATOM   3501 C CB  . PRO B 2 233 ? 152.790 137.068 164.414 1.00 64.86  ?  236 PRO B CB  1 
ATOM   3502 C CG  . PRO B 2 233 ? 152.884 137.641 163.046 1.00 64.86  ?  236 PRO B CG  1 
ATOM   3503 C CD  . PRO B 2 233 ? 152.873 139.131 163.222 1.00 64.86  ?  236 PRO B CD  1 
ATOM   3504 N N   . ASN B 2 234 ? 153.198 138.955 167.025 1.00 69.98  ?  237 ASN B N   1 
ATOM   3505 C CA  . ASN B 2 234 ? 153.511 139.139 168.438 1.00 69.98  ?  237 ASN B CA  1 
ATOM   3506 C C   . ASN B 2 234 ? 152.323 139.730 169.187 1.00 69.98  ?  237 ASN B C   1 
ATOM   3507 O O   . ASN B 2 234 ? 152.015 139.313 170.310 1.00 69.98  ?  237 ASN B O   1 
ATOM   3508 C CB  . ASN B 2 234 ? 154.742 140.036 168.582 1.00 69.98  ?  237 ASN B CB  1 
ATOM   3509 C CG  . ASN B 2 234 ? 155.258 140.107 170.008 1.00 69.98  ?  237 ASN B CG  1 
ATOM   3510 O OD1 . ASN B 2 234 ? 154.693 139.509 170.922 1.00 69.98  ?  237 ASN B OD1 1 
ATOM   3511 N ND2 . ASN B 2 234 ? 156.342 140.849 170.203 1.00 69.98  ?  237 ASN B ND2 1 
ATOM   3512 N N   . GLY B 2 235 ? 151.636 140.693 168.577 1.00 68.37  ?  238 GLY B N   1 
ATOM   3513 C CA  . GLY B 2 235 ? 150.533 141.378 169.213 1.00 68.37  ?  238 GLY B CA  1 
ATOM   3514 C C   . GLY B 2 235 ? 150.877 142.720 169.817 1.00 68.37  ?  238 GLY B C   1 
ATOM   3515 O O   . GLY B 2 235 ? 149.987 143.374 170.374 1.00 68.37  ?  238 GLY B O   1 
ATOM   3516 N N   . ASN B 2 236 ? 152.134 143.151 169.730 1.00 70.69  ?  239 ASN B N   1 
ATOM   3517 C CA  . ASN B 2 236 ? 152.564 144.440 170.256 1.00 70.69  ?  239 ASN B CA  1 
ATOM   3518 C C   . ASN B 2 236 ? 152.750 145.483 169.163 1.00 70.69  ?  239 ASN B C   1 
ATOM   3519 O O   . ASN B 2 236 ? 153.253 146.575 169.441 1.00 70.69  ?  239 ASN B O   1 
ATOM   3520 C CB  . ASN B 2 236 ? 153.859 144.278 171.054 1.00 70.69  ?  239 ASN B CB  1 
ATOM   3521 C CG  . ASN B 2 236 ? 153.671 143.445 172.304 1.00 70.69  ?  239 ASN B CG  1 
ATOM   3522 O OD1 . ASN B 2 236 ? 154.471 142.559 172.600 1.00 70.69  ?  239 ASN B OD1 1 
ATOM   3523 N ND2 . ASN B 2 236 ? 152.607 143.726 173.047 1.00 70.69  ?  239 ASN B ND2 1 
ATOM   3524 N N   . ALA B 2 237 ? 152.358 145.174 167.931 1.00 62.75  ?  240 ALA B N   1 
ATOM   3525 C CA  . ALA B 2 237 ? 152.478 146.107 166.820 1.00 62.75  ?  240 ALA B CA  1 
ATOM   3526 C C   . ALA B 2 237 ? 151.435 145.740 165.779 1.00 62.75  ?  240 ALA B C   1 
ATOM   3527 O O   . ALA B 2 237 ? 150.854 144.653 165.819 1.00 62.75  ?  240 ALA B O   1 
ATOM   3528 C CB  . ALA B 2 237 ? 153.885 146.086 166.214 1.00 62.75  ?  240 ALA B CB  1 
ATOM   3529 N N   . PHE B 2 238 ? 151.192 146.661 164.851 1.00 57.65  ?  241 PHE B N   1 
ATOM   3530 C CA  . PHE B 2 238 ? 150.233 146.392 163.788 1.00 57.65  ?  241 PHE B CA  1 
ATOM   3531 C C   . PHE B 2 238 ? 150.631 147.162 162.539 1.00 57.65  ?  241 PHE B C   1 
ATOM   3532 O O   . PHE B 2 238 ? 151.535 147.999 162.560 1.00 57.65  ?  241 PHE B O   1 
ATOM   3533 C CB  . PHE B 2 238 ? 148.798 146.725 164.223 1.00 57.65  ?  241 PHE B CB  1 
ATOM   3534 C CG  . PHE B 2 238 ? 148.569 148.174 164.536 1.00 57.65  ?  241 PHE B CG  1 
ATOM   3535 C CD1 . PHE B 2 238 ? 148.868 148.683 165.787 1.00 57.65  ?  241 PHE B CD1 1 
ATOM   3536 C CD2 . PHE B 2 238 ? 148.024 149.022 163.590 1.00 57.65  ?  241 PHE B CD2 1 
ATOM   3537 C CE1 . PHE B 2 238 ? 148.648 150.013 166.078 1.00 57.65  ?  241 PHE B CE1 1 
ATOM   3538 C CE2 . PHE B 2 238 ? 147.801 150.352 163.880 1.00 57.65  ?  241 PHE B CE2 1 
ATOM   3539 C CZ  . PHE B 2 238 ? 148.113 150.846 165.123 1.00 57.65  ?  241 PHE B CZ  1 
ATOM   3540 N N   . ALA B 2 239 ? 149.965 146.841 161.433 1.00 54.21  ?  242 ALA B N   1 
ATOM   3541 C CA  . ALA B 2 239 ? 150.235 147.460 160.144 1.00 54.21  ?  242 ALA B CA  1 
ATOM   3542 C C   . ALA B 2 239 ? 148.940 147.978 159.542 1.00 54.21  ?  242 ALA B C   1 
ATOM   3543 O O   . ALA B 2 239 ? 147.900 147.319 159.622 1.00 54.21  ?  242 ALA B O   1 
ATOM   3544 C CB  . ALA B 2 239 ? 150.899 146.476 159.178 1.00 54.21  ?  242 ALA B CB  1 
ATOM   3545 N N   . THR B 2 240 ? 149.012 149.162 158.941 1.00 57.78  ?  243 THR B N   1 
ATOM   3546 C CA  . THR B 2 240 ? 147.866 149.814 158.322 1.00 57.78  ?  243 THR B CA  1 
ATOM   3547 C C   . THR B 2 240 ? 148.178 150.111 156.865 1.00 57.78  ?  243 THR B C   1 
ATOM   3548 O O   . THR B 2 240 ? 149.271 150.588 156.545 1.00 57.78  ?  243 THR B O   1 
ATOM   3549 C CB  . THR B 2 240 ? 147.509 151.116 159.042 1.00 57.78  ?  243 THR B CB  1 
ATOM   3550 O OG1 . THR B 2 240 ? 148.576 152.057 158.881 1.00 57.78  ?  243 THR B OG1 1 
ATOM   3551 C CG2 . THR B 2 240 ? 147.287 150.870 160.514 1.00 57.78  ?  243 THR B CG2 1 
ATOM   3552 N N   . GLY B 2 241 ? 147.219 149.837 155.990 1.00 58.74  ?  244 GLY B N   1 
ATOM   3553 C CA  . GLY B 2 241 ? 147.299 150.215 154.587 1.00 58.74  ?  244 GLY B CA  1 
ATOM   3554 C C   . GLY B 2 241 ? 146.273 151.295 154.299 1.00 58.74  ?  244 GLY B C   1 
ATOM   3555 O O   . GLY B 2 241 ? 145.151 151.242 154.806 1.00 58.74  ?  244 GLY B O   1 
ATOM   3556 N N   . SER B 2 242 ? 146.662 152.277 153.489 1.00 61.47  ?  245 SER B N   1 
ATOM   3557 C CA  . SER B 2 242 ? 145.781 153.411 153.241 1.00 61.47  ?  245 SER B CA  1 
ATOM   3558 C C   . SER B 2 242 ? 145.684 153.759 151.762 1.00 61.47  ?  245 SER B C   1 
ATOM   3559 O O   . SER B 2 242 ? 146.211 153.041 150.908 1.00 61.47  ?  245 SER B O   1 
ATOM   3560 C CB  . SER B 2 242 ? 146.252 154.630 154.030 1.00 61.47  ?  245 SER B CB  1 
ATOM   3561 O OG  . SER B 2 242 ? 147.576 154.978 153.675 1.00 61.47  ?  245 SER B OG  1 
ATOM   3562 N N   . ASP B 2 243 ? 145.004 154.864 151.458 1.00 66.37  ?  246 ASP B N   1 
ATOM   3563 C CA  . ASP B 2 243 ? 144.799 155.300 150.084 1.00 66.37  ?  246 ASP B CA  1 
ATOM   3564 C C   . ASP B 2 243 ? 145.953 156.127 149.537 1.00 66.37  ?  246 ASP B C   1 
ATOM   3565 O O   . ASP B 2 243 ? 145.963 156.425 148.338 1.00 66.37  ?  246 ASP B O   1 
ATOM   3566 C CB  . ASP B 2 243 ? 143.503 156.108 149.981 1.00 66.37  ?  246 ASP B CB  1 
ATOM   3567 C CG  . ASP B 2 243 ? 142.311 155.253 149.602 1.00 66.37  ?  246 ASP B CG  1 
ATOM   3568 O OD1 . ASP B 2 243 ? 142.514 154.188 148.984 1.00 66.37  ?  246 ASP B OD1 1 
ATOM   3569 O OD2 . ASP B 2 243 ? 141.171 155.647 149.923 1.00 66.37  -1 246 ASP B OD2 1 
ATOM   3570 N N   . ASP B 2 244 ? 146.919 156.507 150.373 1.00 67.16  ?  247 ASP B N   1 
ATOM   3571 C CA  . ASP B 2 244 ? 148.050 157.312 149.936 1.00 67.16  ?  247 ASP B CA  1 
ATOM   3572 C C   . ASP B 2 244 ? 149.224 156.465 149.458 1.00 67.16  ?  247 ASP B C   1 
ATOM   3573 O O   . ASP B 2 244 ? 150.366 156.939 149.482 1.00 67.16  ?  247 ASP B O   1 
ATOM   3574 C CB  . ASP B 2 244 ? 148.499 158.252 151.058 1.00 67.16  ?  247 ASP B CB  1 
ATOM   3575 C CG  . ASP B 2 244 ? 148.893 157.512 152.318 1.00 67.16  ?  247 ASP B CG  1 
ATOM   3576 O OD1 . ASP B 2 244 ? 148.657 156.290 152.389 1.00 67.16  ?  247 ASP B OD1 1 
ATOM   3577 O OD2 . ASP B 2 244 ? 149.440 158.152 153.238 1.00 67.16  -1 247 ASP B OD2 1 
ATOM   3578 N N   . ALA B 2 245 ? 148.965 155.228 149.029 1.00 67.70  ?  248 ALA B N   1 
ATOM   3579 C CA  . ALA B 2 245 ? 149.994 154.335 148.494 1.00 67.70  ?  248 ALA B CA  1 
ATOM   3580 C C   . ALA B 2 245 ? 151.126 154.119 149.494 1.00 67.70  ?  248 ALA B C   1 
ATOM   3581 O O   . ALA B 2 245 ? 152.303 154.081 149.129 1.00 67.70  ?  248 ALA B O   1 
ATOM   3582 C CB  . ALA B 2 245 ? 150.541 154.855 147.164 1.00 67.70  ?  248 ALA B CB  1 
ATOM   3583 N N   . THR B 2 246 ? 150.771 153.973 150.767 1.00 62.88  ?  249 THR B N   1 
ATOM   3584 C CA  . THR B 2 246 ? 151.767 153.796 151.813 1.00 62.88  ?  249 THR B CA  1 
ATOM   3585 C C   . THR B 2 246 ? 151.217 152.872 152.888 1.00 62.88  ?  249 THR B C   1 
ATOM   3586 O O   . THR B 2 246 ? 150.108 153.087 153.384 1.00 62.88  ?  249 THR B O   1 
ATOM   3587 C CB  . THR B 2 246 ? 152.161 155.143 152.428 1.00 62.88  ?  249 THR B CB  1 
ATOM   3588 O OG1 . THR B 2 246 ? 152.833 155.941 151.446 1.00 62.88  ?  249 THR B OG1 1 
ATOM   3589 C CG2 . THR B 2 246 ? 153.075 154.941 153.619 1.00 62.88  ?  249 THR B CG2 1 
ATOM   3590 N N   . CYS B 2 247 ? 151.990 151.850 153.238 1.00 62.10  ?  250 CYS B N   1 
ATOM   3591 C CA  . CYS B 2 247 ? 151.712 151.030 154.405 1.00 62.10  ?  250 CYS B CA  1 
ATOM   3592 C C   . CYS B 2 247 ? 152.544 151.539 155.573 1.00 62.10  ?  250 CYS B C   1 
ATOM   3593 O O   . CYS B 2 247 ? 153.594 152.153 155.382 1.00 62.10  ?  250 CYS B O   1 
ATOM   3594 C CB  . CYS B 2 247 ? 152.024 149.556 154.138 1.00 62.10  ?  250 CYS B CB  1 
ATOM   3595 S SG  . CYS B 2 247 ? 150.832 148.720 153.072 1.00 62.10  ?  250 CYS B SG  1 
ATOM   3596 N N   . ARG B 2 248 ? 152.069 151.292 156.787 1.00 61.62  ?  251 ARG B N   1 
ATOM   3597 C CA  . ARG B 2 248 ? 152.761 151.802 157.960 1.00 61.62  ?  251 ARG B CA  1 
ATOM   3598 C C   . ARG B 2 248 ? 152.682 150.799 159.098 1.00 61.62  ?  251 ARG B C   1 
ATOM   3599 O O   . ARG B 2 248 ? 151.598 150.329 159.449 1.00 61.62  ?  251 ARG B O   1 
ATOM   3600 C CB  . ARG B 2 248 ? 152.180 153.150 158.400 1.00 61.62  ?  251 ARG B CB  1 
ATOM   3601 C CG  . ARG B 2 248 ? 152.656 154.320 157.558 1.00 61.62  ?  251 ARG B CG  1 
ATOM   3602 C CD  . ARG B 2 248 ? 151.714 155.503 157.661 1.00 61.62  ?  251 ARG B CD  1 
ATOM   3603 N NE  . ARG B 2 248 ? 151.922 156.457 156.579 1.00 61.62  ?  251 ARG B NE  1 
ATOM   3604 C CZ  . ARG B 2 248 ? 152.772 157.473 156.632 1.00 61.62  ?  251 ARG B CZ  1 
ATOM   3605 N NH1 . ARG B 2 248 ? 153.513 157.699 157.704 1.00 61.62  1  251 ARG B NH1 1 
ATOM   3606 N NH2 . ARG B 2 248 ? 152.880 158.284 155.583 1.00 61.62  ?  251 ARG B NH2 1 
ATOM   3607 N N   . LEU B 2 249 ? 153.838 150.484 159.671 1.00 60.68  ?  252 LEU B N   1 
ATOM   3608 C CA  . LEU B 2 249 ? 153.939 149.634 160.849 1.00 60.68  ?  252 LEU B CA  1 
ATOM   3609 C C   . LEU B 2 249 ? 154.004 150.538 162.073 1.00 60.68  ?  252 LEU B C   1 
ATOM   3610 O O   . LEU B 2 249 ? 154.979 151.283 162.250 1.00 60.68  ?  252 LEU B O   1 
ATOM   3611 C CB  . LEU B 2 249 ? 155.165 148.729 160.770 1.00 60.68  ?  252 LEU B CB  1 
ATOM   3612 C CG  . LEU B 2 249 ? 155.383 147.793 161.959 1.00 60.68  ?  252 LEU B CG  1 
ATOM   3613 C CD1 . LEU B 2 249 ? 154.544 146.537 161.816 1.00 60.68  ?  252 LEU B CD1 1 
ATOM   3614 C CD2 . LEU B 2 249 ? 156.853 147.444 162.106 1.00 60.68  ?  252 LEU B CD2 1 
ATOM   3615 N N   . PHE B 2 250 ? 152.955 150.477 162.893 1.00 62.51  ?  253 PHE B N   1 
ATOM   3616 C CA  . PHE B 2 250 ? 152.832 151.199 164.150 1.00 62.51  ?  253 PHE B CA  1 
ATOM   3617 C C   . PHE B 2 250 ? 153.086 150.259 165.320 1.00 62.51  ?  253 PHE B C   1 
ATOM   3618 O O   . PHE B 2 250 ? 152.896 149.043 165.220 1.00 62.51  ?  253 PHE B O   1 
ATOM   3619 C CB  . PHE B 2 250 ? 151.439 151.815 164.301 1.00 62.51  ?  253 PHE B CB  1 
ATOM   3620 C CG  . PHE B 2 250 ? 151.132 152.889 163.303 1.00 62.51  ?  253 PHE B CG  1 
ATOM   3621 C CD1 . PHE B 2 250 ? 151.562 154.187 163.508 1.00 62.51  ?  253 PHE B CD1 1 
ATOM   3622 C CD2 . PHE B 2 250 ? 150.395 152.605 162.168 1.00 62.51  ?  253 PHE B CD2 1 
ATOM   3623 C CE1 . PHE B 2 250 ? 151.273 155.177 162.595 1.00 62.51  ?  253 PHE B CE1 1 
ATOM   3624 C CE2 . PHE B 2 250 ? 150.103 153.591 161.252 1.00 62.51  ?  253 PHE B CE2 1 
ATOM   3625 C CZ  . PHE B 2 250 ? 150.543 154.879 161.465 1.00 62.51  ?  253 PHE B CZ  1 
ATOM   3626 N N   . ASP B 2 251 ? 153.476 150.846 166.448 1.00 76.13  ?  254 ASP B N   1 
ATOM   3627 C CA  . ASP B 2 251 ? 153.882 150.110 167.637 1.00 76.13  ?  254 ASP B CA  1 
ATOM   3628 C C   . ASP B 2 251 ? 152.931 150.415 168.784 1.00 76.13  ?  254 ASP B C   1 
ATOM   3629 O O   . ASP B 2 251 ? 152.681 151.584 169.094 1.00 76.13  ?  254 ASP B O   1 
ATOM   3630 C CB  . ASP B 2 251 ? 155.308 150.482 168.031 1.00 76.13  ?  254 ASP B CB  1 
ATOM   3631 C CG  . ASP B 2 251 ? 155.919 149.501 168.996 1.00 76.13  ?  254 ASP B CG  1 
ATOM   3632 O OD1 . ASP B 2 251 ? 155.253 148.509 169.355 1.00 76.13  ?  254 ASP B OD1 1 
ATOM   3633 O OD2 . ASP B 2 251 ? 157.077 149.724 169.392 1.00 76.13  -1 254 ASP B OD2 1 
ATOM   3634 N N   . LEU B 2 252 ? 152.408 149.362 169.416 1.00 72.21  ?  255 LEU B N   1 
ATOM   3635 C CA  . LEU B 2 252 ? 151.493 149.552 170.538 1.00 72.21  ?  255 LEU B CA  1 
ATOM   3636 C C   . LEU B 2 252 ? 152.232 150.028 171.783 1.00 72.21  ?  255 LEU B C   1 
ATOM   3637 O O   . LEU B 2 252 ? 151.781 150.953 172.468 1.00 72.21  ?  255 LEU B O   1 
ATOM   3638 C CB  . LEU B 2 252 ? 150.742 148.254 170.828 1.00 72.21  ?  255 LEU B CB  1 
ATOM   3639 C CG  . LEU B 2 252 ? 149.801 147.759 169.732 1.00 72.21  ?  255 LEU B CG  1 
ATOM   3640 C CD1 . LEU B 2 252 ? 149.048 146.526 170.195 1.00 72.21  ?  255 LEU B CD1 1 
ATOM   3641 C CD2 . LEU B 2 252 ? 148.839 148.858 169.342 1.00 72.21  ?  255 LEU B CD2 1 
ATOM   3642 N N   . ARG B 2 253 ? 153.368 149.403 172.096 1.00 82.43  ?  256 ARG B N   1 
ATOM   3643 C CA  . ARG B 2 253 ? 154.065 149.729 173.337 1.00 82.43  ?  256 ARG B CA  1 
ATOM   3644 C C   . ARG B 2 253 ? 154.759 151.082 173.250 1.00 82.43  ?  256 ARG B C   1 
ATOM   3645 O O   . ARG B 2 253 ? 154.741 151.856 174.214 1.00 82.43  ?  256 ARG B O   1 
ATOM   3646 C CB  . ARG B 2 253 ? 155.068 148.628 173.681 1.00 82.43  ?  256 ARG B CB  1 
ATOM   3647 C CG  . ARG B 2 253 ? 154.500 147.546 174.584 1.00 82.43  ?  256 ARG B CG  1 
ATOM   3648 C CD  . ARG B 2 253 ? 155.509 146.439 174.836 1.00 82.43  ?  256 ARG B CD  1 
ATOM   3649 N NE  . ARG B 2 253 ? 156.036 145.884 173.596 1.00 82.43  ?  256 ARG B NE  1 
ATOM   3650 C CZ  . ARG B 2 253 ? 157.238 145.340 173.471 1.00 82.43  ?  256 ARG B CZ  1 
ATOM   3651 N NH1 . ARG B 2 253 ? 158.070 145.258 174.497 1.00 82.43  1  256 ARG B NH1 1 
ATOM   3652 N NH2 . ARG B 2 253 ? 157.616 144.865 172.288 1.00 82.43  ?  256 ARG B NH2 1 
ATOM   3653 N N   . ALA B 2 254 ? 155.376 151.388 172.109 1.00 83.42  ?  257 ALA B N   1 
ATOM   3654 C CA  . ALA B 2 254 ? 156.026 152.681 171.942 1.00 83.42  ?  257 ALA B CA  1 
ATOM   3655 C C   . ALA B 2 254 ? 155.043 153.789 171.594 1.00 83.42  ?  257 ALA B C   1 
ATOM   3656 O O   . ALA B 2 254 ? 155.390 154.966 171.732 1.00 83.42  ?  257 ALA B O   1 
ATOM   3657 C CB  . ALA B 2 254 ? 157.106 152.597 170.862 1.00 83.42  ?  257 ALA B CB  1 
ATOM   3658 N N   . ASP B 2 255 ? 153.830 153.437 171.159 1.00 85.20  ?  258 ASP B N   1 
ATOM   3659 C CA  . ASP B 2 255 ? 152.795 154.411 170.811 1.00 85.20  ?  258 ASP B CA  1 
ATOM   3660 C C   . ASP B 2 255 ? 153.297 155.401 169.761 1.00 85.20  ?  258 ASP B C   1 
ATOM   3661 O O   . ASP B 2 255 ? 153.031 156.602 169.831 1.00 85.20  ?  258 ASP B O   1 
ATOM   3662 C CB  . ASP B 2 255 ? 152.287 155.142 172.057 1.00 85.20  ?  258 ASP B CB  1 
ATOM   3663 C CG  . ASP B 2 255 ? 150.965 155.846 171.826 1.00 85.20  ?  258 ASP B CG  1 
ATOM   3664 O OD1 . ASP B 2 255 ? 149.925 155.157 171.784 1.00 85.20  ?  258 ASP B OD1 1 
ATOM   3665 O OD2 . ASP B 2 255 ? 150.963 157.087 171.695 1.00 85.20  -1 258 ASP B OD2 1 
ATOM   3666 N N   . GLN B 2 256 ? 154.033 154.893 168.776 1.00 81.63  ?  259 GLN B N   1 
ATOM   3667 C CA  . GLN B 2 256 ? 154.661 155.741 167.773 1.00 81.63  ?  259 GLN B CA  1 
ATOM   3668 C C   . GLN B 2 256 ? 154.511 155.093 166.404 1.00 81.63  ?  259 GLN B C   1 
ATOM   3669 O O   . GLN B 2 256 ? 153.797 154.101 166.229 1.00 81.63  ?  259 GLN B O   1 
ATOM   3670 C CB  . GLN B 2 256 ? 156.143 155.978 168.085 1.00 81.63  ?  259 GLN B CB  1 
ATOM   3671 C CG  . GLN B 2 256 ? 156.422 156.812 169.307 1.00 81.63  ?  259 GLN B CG  1 
ATOM   3672 C CD  . GLN B 2 256 ? 157.857 157.279 169.344 1.00 81.63  ?  259 GLN B CD  1 
ATOM   3673 O OE1 . GLN B 2 256 ? 158.525 157.343 168.313 1.00 81.63  ?  259 GLN B OE1 1 
ATOM   3674 N NE2 . GLN B 2 256 ? 158.345 157.598 170.532 1.00 81.63  ?  259 GLN B NE2 1 
ATOM   3675 N N   . GLU B 2 257 ? 155.202 155.678 165.434 1.00 74.78  ?  260 GLU B N   1 
ATOM   3676 C CA  . GLU B 2 257 ? 155.348 155.124 164.098 1.00 74.78  ?  260 GLU B CA  1 
ATOM   3677 C C   . GLU B 2 257 ? 156.680 154.393 164.015 1.00 74.78  ?  260 GLU B C   1 
ATOM   3678 O O   . GLU B 2 257 ? 157.738 155.007 164.182 1.00 74.78  ?  260 GLU B O   1 
ATOM   3679 C CB  . GLU B 2 257 ? 155.300 156.237 163.053 1.00 74.78  ?  260 GLU B CB  1 
ATOM   3680 C CG  . GLU B 2 257 ? 155.272 155.762 161.622 1.00 74.78  ?  260 GLU B CG  1 
ATOM   3681 C CD  . GLU B 2 257 ? 154.444 156.666 160.742 1.00 74.78  ?  260 GLU B CD  1 
ATOM   3682 O OE1 . GLU B 2 257 ? 154.440 157.891 160.981 1.00 74.78  ?  260 GLU B OE1 1 
ATOM   3683 O OE2 . GLU B 2 257 ? 153.804 156.156 159.806 1.00 74.78  -1 260 GLU B OE2 1 
ATOM   3684 N N   . LEU B 2 258 ? 156.630 153.087 163.757 1.00 69.72  ?  261 LEU B N   1 
ATOM   3685 C CA  . LEU B 2 258 ? 157.847 152.294 163.638 1.00 69.72  ?  261 LEU B CA  1 
ATOM   3686 C C   . LEU B 2 258 ? 158.457 152.395 162.246 1.00 69.72  ?  261 LEU B C   1 
ATOM   3687 O O   . LEU B 2 258 ? 159.639 152.722 162.109 1.00 69.72  ?  261 LEU B O   1 
ATOM   3688 C CB  . LEU B 2 258 ? 157.579 150.826 163.993 1.00 69.72  ?  261 LEU B CB  1 
ATOM   3689 C CG  . LEU B 2 258 ? 157.705 150.466 165.471 1.00 69.72  ?  261 LEU B CG  1 
ATOM   3690 C CD1 . LEU B 2 258 ? 157.695 148.958 165.655 1.00 69.72  ?  261 LEU B CD1 1 
ATOM   3691 C CD2 . LEU B 2 258 ? 158.963 151.075 166.069 1.00 69.72  ?  261 LEU B CD2 1 
ATOM   3692 N N   . MET B 2 259 ? 157.675 152.123 161.205 1.00 70.69  ?  262 MET B N   1 
ATOM   3693 C CA  . MET B 2 259 ? 158.242 152.113 159.862 1.00 70.69  ?  262 MET B CA  1 
ATOM   3694 C C   . MET B 2 259 ? 157.173 152.439 158.829 1.00 70.69  ?  262 MET B C   1 
ATOM   3695 O O   . MET B 2 259 ? 155.977 152.280 159.071 1.00 70.69  ?  262 MET B O   1 
ATOM   3696 C CB  . MET B 2 259 ? 158.913 150.760 159.566 1.00 70.69  ?  262 MET B CB  1 
ATOM   3697 C CG  . MET B 2 259 ? 159.644 150.679 158.235 1.00 70.69  ?  262 MET B CG  1 
ATOM   3698 S SD  . MET B 2 259 ? 160.422 149.082 157.950 1.00 70.69  ?  262 MET B SD  1 
ATOM   3699 C CE  . MET B 2 259 ? 161.780 149.162 159.107 1.00 70.69  ?  262 MET B CE  1 
ATOM   3700 N N   . THR B 2 260 ? 157.624 152.915 157.670 1.00 64.09  ?  263 THR B N   1 
ATOM   3701 C CA  . THR B 2 260 ? 156.758 153.213 156.538 1.00 64.09  ?  263 THR B CA  1 
ATOM   3702 C C   . THR B 2 260 ? 157.244 152.452 155.311 1.00 64.09  ?  263 THR B C   1 
ATOM   3703 O O   . THR B 2 260 ? 158.442 152.445 155.010 1.00 64.09  ?  263 THR B O   1 
ATOM   3704 C CB  . THR B 2 260 ? 156.710 154.721 156.261 1.00 64.09  ?  263 THR B CB  1 
ATOM   3705 O OG1 . THR B 2 260 ? 155.938 154.971 155.081 1.00 64.09  ?  263 THR B OG1 1 
ATOM   3706 C CG2 . THR B 2 260 ? 158.109 155.300 156.096 1.00 64.09  ?  263 THR B CG2 1 
ATOM   3707 N N   . TYR B 2 261 ? 156.315 151.796 154.622 1.00 61.96  ?  264 TYR B N   1 
ATOM   3708 C CA  . TYR B 2 261 ? 156.587 151.032 153.410 1.00 61.96  ?  264 TYR B CA  1 
ATOM   3709 C C   . TYR B 2 261 ? 155.936 151.763 152.244 1.00 61.96  ?  264 TYR B C   1 
ATOM   3710 O O   . TYR B 2 261 ? 154.704 151.812 152.146 1.00 61.96  ?  264 TYR B O   1 
ATOM   3711 C CB  . TYR B 2 261 ? 156.047 149.609 153.526 1.00 61.96  ?  264 TYR B CB  1 
ATOM   3712 C CG  . TYR B 2 261 ? 156.352 148.933 154.841 1.00 61.96  ?  264 TYR B CG  1 
ATOM   3713 C CD1 . TYR B 2 261 ? 157.560 148.285 155.046 1.00 61.96  ?  264 TYR B CD1 1 
ATOM   3714 C CD2 . TYR B 2 261 ? 155.433 148.948 155.880 1.00 61.96  ?  264 TYR B CD2 1 
ATOM   3715 C CE1 . TYR B 2 261 ? 157.840 147.666 156.244 1.00 61.96  ?  264 TYR B CE1 1 
ATOM   3716 C CE2 . TYR B 2 261 ? 155.708 148.335 157.083 1.00 61.96  ?  264 TYR B CE2 1 
ATOM   3717 C CZ  . TYR B 2 261 ? 156.913 147.696 157.260 1.00 61.96  ?  264 TYR B CZ  1 
ATOM   3718 O OH  . TYR B 2 261 ? 157.191 147.082 158.457 1.00 61.96  ?  264 TYR B OH  1 
ATOM   3719 N N   . SER B 2 262 ? 156.759 152.330 151.366 1.00 68.62  ?  265 SER B N   1 
ATOM   3720 C CA  . SER B 2 262 ? 156.260 153.058 150.212 1.00 68.62  ?  265 SER B CA  1 
ATOM   3721 C C   . SER B 2 262 ? 157.320 153.055 149.123 1.00 68.62  ?  265 SER B C   1 
ATOM   3722 O O   . SER B 2 262 ? 158.519 152.990 149.402 1.00 68.62  ?  265 SER B O   1 
ATOM   3723 C CB  . SER B 2 262 ? 155.880 154.498 150.576 1.00 68.62  ?  265 SER B CB  1 
ATOM   3724 O OG  . SER B 2 262 ? 157.020 155.238 150.976 1.00 68.62  ?  265 SER B OG  1 
ATOM   3725 N N   . HIS B 2 263 ? 156.861 153.125 147.876 1.00 78.26  ?  266 HIS B N   1 
ATOM   3726 C CA  . HIS B 2 263 ? 157.743 153.197 146.723 1.00 78.26  ?  266 HIS B CA  1 
ATOM   3727 C C   . HIS B 2 263 ? 157.230 154.272 145.778 1.00 78.26  ?  266 HIS B C   1 
ATOM   3728 O O   . HIS B 2 263 ? 156.023 154.507 145.678 1.00 78.26  ?  266 HIS B O   1 
ATOM   3729 C CB  . HIS B 2 263 ? 157.837 151.850 145.996 1.00 78.26  ?  266 HIS B CB  1 
ATOM   3730 C CG  . HIS B 2 263 ? 159.116 151.658 145.242 1.00 78.26  ?  266 HIS B CG  1 
ATOM   3731 N ND1 . HIS B 2 263 ? 159.282 152.073 143.939 1.00 78.26  ?  266 HIS B ND1 1 
ATOM   3732 C CD2 . HIS B 2 263 ? 160.291 151.093 145.609 1.00 78.26  ?  266 HIS B CD2 1 
ATOM   3733 C CE1 . HIS B 2 263 ? 160.503 151.773 143.535 1.00 78.26  ?  266 HIS B CE1 1 
ATOM   3734 N NE2 . HIS B 2 263 ? 161.136 151.178 144.530 1.00 78.26  ?  266 HIS B NE2 1 
ATOM   3735 N N   . ASP B 2 264 ? 158.164 154.930 145.087 1.00 81.15  ?  267 ASP B N   1 
ATOM   3736 C CA  . ASP B 2 264 ? 157.783 156.000 144.170 1.00 81.15  ?  267 ASP B CA  1 
ATOM   3737 C C   . ASP B 2 264 ? 156.971 155.473 142.995 1.00 81.15  ?  267 ASP B C   1 
ATOM   3738 O O   . ASP B 2 264 ? 156.131 156.196 142.448 1.00 81.15  ?  267 ASP B O   1 
ATOM   3739 C CB  . ASP B 2 264 ? 159.027 156.732 143.671 1.00 81.15  ?  267 ASP B CB  1 
ATOM   3740 C CG  . ASP B 2 264 ? 159.756 157.461 144.781 1.00 81.15  ?  267 ASP B CG  1 
ATOM   3741 O OD1 . ASP B 2 264 ? 159.399 158.623 145.064 1.00 81.15  ?  267 ASP B OD1 1 
ATOM   3742 O OD2 . ASP B 2 264 ? 160.686 156.871 145.370 1.00 81.15  -1 267 ASP B OD2 1 
ATOM   3743 N N   . ASN B 2 265 ? 157.202 154.222 142.593 1.00 80.75  ?  268 ASN B N   1 
ATOM   3744 C CA  . ASN B 2 265 ? 156.454 153.635 141.489 1.00 80.75  ?  268 ASN B CA  1 
ATOM   3745 C C   . ASN B 2 265 ? 155.020 153.288 141.863 1.00 80.75  ?  268 ASN B C   1 
ATOM   3746 O O   . ASN B 2 265 ? 154.234 152.946 140.974 1.00 80.75  ?  268 ASN B O   1 
ATOM   3747 C CB  . ASN B 2 265 ? 157.168 152.382 140.979 1.00 80.75  ?  268 ASN B CB  1 
ATOM   3748 C CG  . ASN B 2 265 ? 158.464 152.702 140.264 1.00 80.75  ?  268 ASN B CG  1 
ATOM   3749 O OD1 . ASN B 2 265 ? 158.540 153.654 139.488 1.00 80.75  ?  268 ASN B OD1 1 
ATOM   3750 N ND2 . ASN B 2 265 ? 159.493 151.904 140.521 1.00 80.75  ?  268 ASN B ND2 1 
ATOM   3751 N N   . ILE B 2 266 ? 154.662 153.363 143.142 1.00 74.89  ?  269 ILE B N   1 
ATOM   3752 C CA  . ILE B 2 266 ? 153.323 153.030 143.614 1.00 74.89  ?  269 ILE B CA  1 
ATOM   3753 C C   . ILE B 2 266 ? 152.600 154.326 143.947 1.00 74.89  ?  269 ILE B C   1 
ATOM   3754 O O   . ILE B 2 266 ? 153.097 155.139 144.737 1.00 74.89  ?  269 ILE B O   1 
ATOM   3755 C CB  . ILE B 2 266 ? 153.367 152.098 144.833 1.00 74.89  ?  269 ILE B CB  1 
ATOM   3756 C CG1 . ILE B 2 266 ? 154.218 150.865 144.533 1.00 74.89  ?  269 ILE B CG1 1 
ATOM   3757 C CG2 . ILE B 2 266 ? 151.963 151.694 145.233 1.00 74.89  ?  269 ILE B CG2 1 
ATOM   3758 C CD1 . ILE B 2 266 ? 154.631 150.100 145.767 1.00 74.89  ?  269 ILE B CD1 1 
ATOM   3759 N N   . ILE B 2 267 ? 151.427 154.519 143.347 1.00 74.43  ?  270 ILE B N   1 
ATOM   3760 C CA  . ILE B 2 267 ? 150.624 155.713 143.583 1.00 74.43  ?  270 ILE B CA  1 
ATOM   3761 C C   . ILE B 2 267 ? 149.200 155.302 143.931 1.00 74.43  ?  270 ILE B C   1 
ATOM   3762 O O   . ILE B 2 267 ? 148.357 156.148 144.248 1.00 74.43  ?  270 ILE B O   1 
ATOM   3763 C CB  . ILE B 2 267 ? 150.645 156.651 142.363 1.00 74.43  ?  270 ILE B CB  1 
ATOM   3764 C CG1 . ILE B 2 267 ? 150.208 155.897 141.106 1.00 74.43  ?  270 ILE B CG1 1 
ATOM   3765 C CG2 . ILE B 2 267 ? 152.028 157.254 142.176 1.00 74.43  ?  270 ILE B CG2 1 
ATOM   3766 C CD1 . ILE B 2 267 ? 150.184 156.752 139.860 1.00 74.43  ?  270 ILE B CD1 1 
ATOM   3767 N N   . CYS B 2 268 ? 148.925 154.004 143.875 1.00 69.02  ?  271 CYS B N   1 
ATOM   3768 C CA  . CYS B 2 268 ? 147.594 153.481 144.142 1.00 69.02  ?  271 CYS B CA  1 
ATOM   3769 C C   . CYS B 2 268 ? 147.462 153.055 145.599 1.00 69.02  ?  271 CYS B C   1 
ATOM   3770 O O   . CYS B 2 268 ? 148.432 152.636 146.235 1.00 69.02  ?  271 CYS B O   1 
ATOM   3771 C CB  . CYS B 2 268 ? 147.291 152.297 143.226 1.00 69.02  ?  271 CYS B CB  1 
ATOM   3772 S SG  . CYS B 2 268 ? 148.320 150.851 143.537 1.00 69.02  ?  271 CYS B SG  1 
ATOM   3773 N N   . GLY B 2 269 ? 146.243 153.153 146.118 1.00 62.28  ?  272 GLY B N   1 
ATOM   3774 C CA  . GLY B 2 269 ? 145.994 152.835 147.507 1.00 62.28  ?  272 GLY B CA  1 
ATOM   3775 C C   . GLY B 2 269 ? 146.044 151.345 147.791 1.00 62.28  ?  272 GLY B C   1 
ATOM   3776 O O   . GLY B 2 269 ? 146.024 150.497 146.899 1.00 62.28  ?  272 GLY B O   1 
ATOM   3777 N N   . ILE B 2 270 ? 146.110 151.028 149.082 1.00 56.43  ?  273 ILE B N   1 
ATOM   3778 C CA  . ILE B 2 270 ? 146.164 149.653 149.564 1.00 56.43  ?  273 ILE B CA  1 
ATOM   3779 C C   . ILE B 2 270 ? 144.772 149.242 150.017 1.00 56.43  ?  273 ILE B C   1 
ATOM   3780 O O   . ILE B 2 270 ? 144.113 149.973 150.766 1.00 56.43  ?  273 ILE B O   1 
ATOM   3781 C CB  . ILE B 2 270 ? 147.180 149.495 150.709 1.00 56.43  ?  273 ILE B CB  1 
ATOM   3782 C CG1 . ILE B 2 270 ? 148.601 149.792 150.230 1.00 56.43  ?  273 ILE B CG1 1 
ATOM   3783 C CG2 . ILE B 2 270 ? 147.106 148.100 151.296 1.00 56.43  ?  273 ILE B CG2 1 
ATOM   3784 C CD1 . ILE B 2 270 ? 149.011 151.236 150.348 1.00 56.43  ?  273 ILE B CD1 1 
ATOM   3785 N N   . THR B 2 271 ? 144.323 148.074 149.563 1.00 54.02  ?  274 THR B N   1 
ATOM   3786 C CA  . THR B 2 271 ? 143.018 147.550 149.942 1.00 54.02  ?  274 THR B CA  1 
ATOM   3787 C C   . THR B 2 271 ? 143.082 146.508 151.047 1.00 54.02  ?  274 THR B C   1 
ATOM   3788 O O   . THR B 2 271 ? 142.095 146.327 151.767 1.00 54.02  ?  274 THR B O   1 
ATOM   3789 C CB  . THR B 2 271 ? 142.319 146.934 148.727 1.00 54.02  ?  274 THR B CB  1 
ATOM   3790 O OG1 . THR B 2 271 ? 143.177 145.958 148.128 1.00 54.02  ?  274 THR B OG1 1 
ATOM   3791 C CG2 . THR B 2 271 ? 141.986 148.003 147.708 1.00 54.02  ?  274 THR B CG2 1 
ATOM   3792 N N   . SER B 2 272 ? 144.210 145.819 151.201 1.00 53.32  ?  275 SER B N   1 
ATOM   3793 C CA  . SER B 2 272 ? 144.318 144.759 152.190 1.00 53.32  ?  275 SER B CA  1 
ATOM   3794 C C   . SER B 2 272 ? 145.762 144.641 152.653 1.00 53.32  ?  275 SER B C   1 
ATOM   3795 O O   . SER B 2 272 ? 146.697 144.820 151.870 1.00 53.32  ?  275 SER B O   1 
ATOM   3796 C CB  . SER B 2 272 ? 143.826 143.424 151.628 1.00 53.32  ?  275 SER B CB  1 
ATOM   3797 O OG  . SER B 2 272 ? 144.375 143.185 150.344 1.00 53.32  ?  275 SER B OG  1 
ATOM   3798 N N   . VAL B 2 273 ? 145.929 144.341 153.938 1.00 52.73  ?  276 VAL B N   1 
ATOM   3799 C CA  . VAL B 2 273 ? 147.237 144.191 154.563 1.00 52.73  ?  276 VAL B CA  1 
ATOM   3800 C C   . VAL B 2 273 ? 147.219 142.934 155.419 1.00 52.73  ?  276 VAL B C   1 
ATOM   3801 O O   . VAL B 2 273 ? 146.257 142.688 156.154 1.00 52.73  ?  276 VAL B O   1 
ATOM   3802 C CB  . VAL B 2 273 ? 147.605 145.426 155.412 1.00 52.73  ?  276 VAL B CB  1 
ATOM   3803 C CG1 . VAL B 2 273 ? 148.792 145.132 156.307 1.00 52.73  ?  276 VAL B CG1 1 
ATOM   3804 C CG2 . VAL B 2 273 ? 147.908 146.609 154.517 1.00 52.73  ?  276 VAL B CG2 1 
ATOM   3805 N N   . SER B 2 274 ? 148.279 142.134 155.321 1.00 54.83  ?  277 SER B N   1 
ATOM   3806 C CA  . SER B 2 274 ? 148.382 140.922 156.117 1.00 54.83  ?  277 SER B CA  1 
ATOM   3807 C C   . SER B 2 274 ? 149.847 140.635 156.410 1.00 54.83  ?  277 SER B C   1 
ATOM   3808 O O   . SER B 2 274 ? 150.746 141.120 155.722 1.00 54.83  ?  277 SER B O   1 
ATOM   3809 C CB  . SER B 2 274 ? 147.730 139.729 155.412 1.00 54.83  ?  277 SER B CB  1 
ATOM   3810 O OG  . SER B 2 274 ? 147.858 138.554 156.191 1.00 54.83  ?  277 SER B OG  1 
ATOM   3811 N N   . PHE B 2 275 ? 150.072 139.833 157.447 1.00 58.24  ?  278 PHE B N   1 
ATOM   3812 C CA  . PHE B 2 275 ? 151.406 139.469 157.899 1.00 58.24  ?  278 PHE B CA  1 
ATOM   3813 C C   . PHE B 2 275 ? 151.635 137.978 157.702 1.00 58.24  ?  278 PHE B C   1 
ATOM   3814 O O   . PHE B 2 275 ? 150.690 137.185 157.681 1.00 58.24  ?  278 PHE B O   1 
ATOM   3815 C CB  . PHE B 2 275 ? 151.608 139.818 159.379 1.00 58.24  ?  278 PHE B CB  1 
ATOM   3816 C CG  . PHE B 2 275 ? 152.259 141.148 159.611 1.00 58.24  ?  278 PHE B CG  1 
ATOM   3817 C CD1 . PHE B 2 275 ? 153.581 141.357 159.265 1.00 58.24  ?  278 PHE B CD1 1 
ATOM   3818 C CD2 . PHE B 2 275 ? 151.552 142.186 160.190 1.00 58.24  ?  278 PHE B CD2 1 
ATOM   3819 C CE1 . PHE B 2 275 ? 154.183 142.579 159.485 1.00 58.24  ?  278 PHE B CE1 1 
ATOM   3820 C CE2 . PHE B 2 275 ? 152.149 143.409 160.412 1.00 58.24  ?  278 PHE B CE2 1 
ATOM   3821 C CZ  . PHE B 2 275 ? 153.466 143.605 160.059 1.00 58.24  ?  278 PHE B CZ  1 
ATOM   3822 N N   . SER B 2 276 ? 152.903 137.601 157.559 1.00 66.26  ?  279 SER B N   1 
ATOM   3823 C CA  . SER B 2 276 ? 153.270 136.196 157.516 1.00 66.26  ?  279 SER B CA  1 
ATOM   3824 C C   . SER B 2 276 ? 153.241 135.615 158.929 1.00 66.26  ?  279 SER B C   1 
ATOM   3825 O O   . SER B 2 276 ? 152.952 136.307 159.909 1.00 66.26  ?  279 SER B O   1 
ATOM   3826 C CB  . SER B 2 276 ? 154.641 136.022 156.870 1.00 66.26  ?  279 SER B CB  1 
ATOM   3827 O OG  . SER B 2 276 ? 155.677 136.201 157.818 1.00 66.26  ?  279 SER B OG  1 
ATOM   3828 N N   . LYS B 2 277 ? 153.538 134.318 159.039 1.00 68.97  ?  280 LYS B N   1 
ATOM   3829 C CA  . LYS B 2 277 ? 153.481 133.663 160.343 1.00 68.97  ?  280 LYS B CA  1 
ATOM   3830 C C   . LYS B 2 277 ? 154.522 134.233 161.298 1.00 68.97  ?  280 LYS B C   1 
ATOM   3831 O O   . LYS B 2 277 ? 154.233 134.458 162.479 1.00 68.97  ?  280 LYS B O   1 
ATOM   3832 C CB  . LYS B 2 277 ? 153.668 132.155 160.186 1.00 68.97  ?  280 LYS B CB  1 
ATOM   3833 C CG  . LYS B 2 277 ? 153.439 131.378 161.470 1.00 68.97  ?  280 LYS B CG  1 
ATOM   3834 C CD  . LYS B 2 277 ? 153.490 129.881 161.231 1.00 68.97  ?  280 LYS B CD  1 
ATOM   3835 C CE  . LYS B 2 277 ? 153.265 129.112 162.520 1.00 68.97  ?  280 LYS B CE  1 
ATOM   3836 N NZ  . LYS B 2 277 ? 151.920 129.383 163.095 1.00 68.97  1  280 LYS B NZ  1 
ATOM   3837 N N   . SER B 2 278 ? 155.739 134.471 160.810 1.00 69.69  ?  281 SER B N   1 
ATOM   3838 C CA  . SER B 2 278 ? 156.796 135.017 161.650 1.00 69.69  ?  281 SER B CA  1 
ATOM   3839 C C   . SER B 2 278 ? 156.772 136.536 161.726 1.00 69.69  ?  281 SER B C   1 
ATOM   3840 O O   . SER B 2 278 ? 157.494 137.108 162.550 1.00 69.69  ?  281 SER B O   1 
ATOM   3841 C CB  . SER B 2 278 ? 158.163 134.557 161.140 1.00 69.69  ?  281 SER B CB  1 
ATOM   3842 O OG  . SER B 2 278 ? 158.404 135.040 159.831 1.00 69.69  ?  281 SER B OG  1 
ATOM   3843 N N   . GLY B 2 279 ? 155.971 137.199 160.896 1.00 67.66  ?  282 GLY B N   1 
ATOM   3844 C CA  . GLY B 2 279 ? 155.922 138.643 160.873 1.00 67.66  ?  282 GLY B CA  1 
ATOM   3845 C C   . GLY B 2 279 ? 157.030 139.311 160.091 1.00 67.66  ?  282 GLY B C   1 
ATOM   3846 O O   . GLY B 2 279 ? 157.066 140.546 160.034 1.00 67.66  ?  282 GLY B O   1 
ATOM   3847 N N   . ARG B 2 280 ? 157.934 138.540 159.484 1.00 66.64  ?  283 ARG B N   1 
ATOM   3848 C CA  . ARG B 2 280 ? 159.029 139.139 158.731 1.00 66.64  ?  283 ARG B CA  1 
ATOM   3849 C C   . ARG B 2 280 ? 158.554 139.706 157.401 1.00 66.64  ?  283 ARG B C   1 
ATOM   3850 O O   . ARG B 2 280 ? 159.085 140.721 156.937 1.00 66.64  ?  283 ARG B O   1 
ATOM   3851 C CB  . ARG B 2 280 ? 160.134 138.107 158.507 1.00 66.64  ?  283 ARG B CB  1 
ATOM   3852 C CG  . ARG B 2 280 ? 161.347 138.639 157.767 1.00 66.64  ?  283 ARG B CG  1 
ATOM   3853 C CD  . ARG B 2 280 ? 162.003 139.774 158.530 1.00 66.64  ?  283 ARG B CD  1 
ATOM   3854 N NE  . ARG B 2 280 ? 163.105 140.365 157.780 1.00 66.64  ?  283 ARG B NE  1 
ATOM   3855 C CZ  . ARG B 2 280 ? 164.354 139.922 157.811 1.00 66.64  ?  283 ARG B CZ  1 
ATOM   3856 N NH1 . ARG B 2 280 ? 164.698 138.878 158.547 1.00 66.64  1  283 ARG B NH1 1 
ATOM   3857 N NH2 . ARG B 2 280 ? 165.280 140.540 157.085 1.00 66.64  ?  283 ARG B NH2 1 
ATOM   3858 N N   . LEU B 2 281 ? 157.563 139.078 156.778 1.00 62.74  ?  284 LEU B N   1 
ATOM   3859 C CA  . LEU B 2 281 ? 157.032 139.515 155.495 1.00 62.74  ?  284 LEU B CA  1 
ATOM   3860 C C   . LEU B 2 281 ? 155.682 140.183 155.706 1.00 62.74  ?  284 LEU B C   1 
ATOM   3861 O O   . LEU B 2 281 ? 154.821 139.642 156.407 1.00 62.74  ?  284 LEU B O   1 
ATOM   3862 C CB  . LEU B 2 281 ? 156.888 138.337 154.530 1.00 62.74  ?  284 LEU B CB  1 
ATOM   3863 C CG  . LEU B 2 281 ? 158.176 137.624 154.120 1.00 62.74  ?  284 LEU B CG  1 
ATOM   3864 C CD1 . LEU B 2 281 ? 157.869 136.505 153.144 1.00 62.74  ?  284 LEU B CD1 1 
ATOM   3865 C CD2 . LEU B 2 281 ? 159.163 138.607 153.520 1.00 62.74  ?  284 LEU B CD2 1 
ATOM   3866 N N   . LEU B 2 282 ? 155.502 141.354 155.103 1.00 56.09  ?  285 LEU B N   1 
ATOM   3867 C CA  . LEU B 2 282 ? 154.238 142.080 155.146 1.00 56.09  ?  285 LEU B CA  1 
ATOM   3868 C C   . LEU B 2 282 ? 153.652 142.093 153.740 1.00 56.09  ?  285 LEU B C   1 
ATOM   3869 O O   . LEU B 2 282 ? 154.237 142.677 152.825 1.00 56.09  ?  285 LEU B O   1 
ATOM   3870 C CB  . LEU B 2 282 ? 154.435 143.499 155.671 1.00 56.09  ?  285 LEU B CB  1 
ATOM   3871 C CG  . LEU B 2 282 ? 153.185 144.379 155.650 1.00 56.09  ?  285 LEU B CG  1 
ATOM   3872 C CD1 . LEU B 2 282 ? 152.204 143.927 156.711 1.00 56.09  ?  285 LEU B CD1 1 
ATOM   3873 C CD2 . LEU B 2 282 ? 153.549 145.837 155.846 1.00 56.09  ?  285 LEU B CD2 1 
ATOM   3874 N N   . LEU B 2 283 ? 152.505 141.449 153.568 1.00 54.43  ?  286 LEU B N   1 
ATOM   3875 C CA  . LEU B 2 283 ? 151.841 141.373 152.276 1.00 54.43  ?  286 LEU B CA  1 
ATOM   3876 C C   . LEU B 2 283 ? 150.764 142.445 152.201 1.00 54.43  ?  286 LEU B C   1 
ATOM   3877 O O   . LEU B 2 283 ? 149.984 142.612 153.143 1.00 54.43  ?  286 LEU B O   1 
ATOM   3878 C CB  . LEU B 2 283 ? 151.235 139.987 152.057 1.00 54.43  ?  286 LEU B CB  1 
ATOM   3879 C CG  . LEU B 2 283 ? 152.237 138.837 151.946 1.00 54.43  ?  286 LEU B CG  1 
ATOM   3880 C CD1 . LEU B 2 283 ? 152.361 138.098 153.267 1.00 54.43  ?  286 LEU B CD1 1 
ATOM   3881 C CD2 . LEU B 2 283 ? 151.832 137.886 150.838 1.00 54.43  ?  286 LEU B CD2 1 
ATOM   3882 N N   . ALA B 2 284 ? 150.732 143.176 151.089 1.00 54.49  ?  287 ALA B N   1 
ATOM   3883 C CA  . ALA B 2 284 ? 149.772 144.256 150.909 1.00 54.49  ?  287 ALA B CA  1 
ATOM   3884 C C   . ALA B 2 284 ? 149.207 144.206 149.500 1.00 54.49  ?  287 ALA B C   1 
ATOM   3885 O O   . ALA B 2 284 ? 149.965 144.207 148.527 1.00 54.49  ?  287 ALA B O   1 
ATOM   3886 C CB  . ALA B 2 284 ? 150.419 145.620 151.169 1.00 54.49  ?  287 ALA B CB  1 
ATOM   3887 N N   . GLY B 2 285 ? 147.881 144.167 149.396 1.00 55.71  ?  288 GLY B N   1 
ATOM   3888 C CA  . GLY B 2 285 ? 147.217 144.208 148.105 1.00 55.71  ?  288 GLY B CA  1 
ATOM   3889 C C   . GLY B 2 285 ? 146.946 145.642 147.681 1.00 55.71  ?  288 GLY B C   1 
ATOM   3890 O O   . GLY B 2 285 ? 146.463 146.455 148.465 1.00 55.71  ?  288 GLY B O   1 
ATOM   3891 N N   . TYR B 2 286 ? 147.256 145.937 146.423 1.00 57.32  ?  289 TYR B N   1 
ATOM   3892 C CA  . TYR B 2 286 ? 147.200 147.293 145.901 1.00 57.32  ?  289 TYR B CA  1 
ATOM   3893 C C   . TYR B 2 286 ? 146.119 147.407 144.835 1.00 57.32  ?  289 TYR B C   1 
ATOM   3894 O O   . TYR B 2 286 ? 145.538 146.415 144.390 1.00 57.32  ?  289 TYR B O   1 
ATOM   3895 C CB  . TYR B 2 286 ? 148.557 147.712 145.323 1.00 57.32  ?  289 TYR B CB  1 
ATOM   3896 C CG  . TYR B 2 286 ? 149.624 147.943 146.366 1.00 57.32  ?  289 TYR B CG  1 
ATOM   3897 C CD1 . TYR B 2 286 ? 150.295 146.879 146.947 1.00 57.32  ?  289 TYR B CD1 1 
ATOM   3898 C CD2 . TYR B 2 286 ? 149.962 149.225 146.767 1.00 57.32  ?  289 TYR B CD2 1 
ATOM   3899 C CE1 . TYR B 2 286 ? 151.271 147.084 147.899 1.00 57.32  ?  289 TYR B CE1 1 
ATOM   3900 C CE2 . TYR B 2 286 ? 150.939 149.441 147.718 1.00 57.32  ?  289 TYR B CE2 1 
ATOM   3901 C CZ  . TYR B 2 286 ? 151.589 148.367 148.281 1.00 57.32  ?  289 TYR B CZ  1 
ATOM   3902 O OH  . TYR B 2 286 ? 152.561 148.579 149.230 1.00 57.32  ?  289 TYR B OH  1 
ATOM   3903 N N   . ASP B 2 287 ? 145.854 148.649 144.428 1.00 63.76  ?  290 ASP B N   1 
ATOM   3904 C CA  . ASP B 2 287 ? 144.892 148.927 143.370 1.00 63.76  ?  290 ASP B CA  1 
ATOM   3905 C C   . ASP B 2 287 ? 145.474 148.752 141.975 1.00 63.76  ?  290 ASP B C   1 
ATOM   3906 O O   . ASP B 2 287 ? 144.712 148.749 141.003 1.00 63.76  ?  290 ASP B O   1 
ATOM   3907 C CB  . ASP B 2 287 ? 144.343 150.347 143.514 1.00 63.76  ?  290 ASP B CB  1 
ATOM   3908 C CG  . ASP B 2 287 ? 143.446 150.505 144.720 1.00 63.76  ?  290 ASP B CG  1 
ATOM   3909 O OD1 . ASP B 2 287 ? 142.719 149.546 145.043 1.00 63.76  ?  290 ASP B OD1 1 
ATOM   3910 O OD2 . ASP B 2 287 ? 143.468 151.586 145.344 1.00 63.76  -1 290 ASP B OD2 1 
ATOM   3911 N N   . ASP B 2 288 ? 146.793 148.605 141.848 1.00 65.11  ?  291 ASP B N   1 
ATOM   3912 C CA  . ASP B 2 288 ? 147.432 148.419 140.553 1.00 65.11  ?  291 ASP B CA  1 
ATOM   3913 C C   . ASP B 2 288 ? 147.416 146.970 140.093 1.00 65.11  ?  291 ASP B C   1 
ATOM   3914 O O   . ASP B 2 288 ? 148.254 146.586 139.268 1.00 65.11  ?  291 ASP B O   1 
ATOM   3915 C CB  . ASP B 2 288 ? 148.869 148.950 140.584 1.00 65.11  ?  291 ASP B CB  1 
ATOM   3916 C CG  . ASP B 2 288 ? 149.710 148.321 141.683 1.00 65.11  ?  291 ASP B CG  1 
ATOM   3917 O OD1 . ASP B 2 288 ? 149.328 147.258 142.213 1.00 65.11  ?  291 ASP B OD1 1 
ATOM   3918 O OD2 . ASP B 2 288 ? 150.766 148.897 142.018 1.00 65.11  -1 291 ASP B OD2 1 
ATOM   3919 N N   . PHE B 2 289 ? 146.500 146.171 140.636 1.00 61.72  ?  292 PHE B N   1 
ATOM   3920 C CA  . PHE B 2 289 ? 146.216 144.776 140.307 1.00 61.72  ?  292 PHE B CA  1 
ATOM   3921 C C   . PHE B 2 289 ? 147.254 143.842 140.917 1.00 61.72  ?  292 PHE B C   1 
ATOM   3922 O O   . PHE B 2 289 ? 147.131 142.623 140.758 1.00 61.72  ?  292 PHE B O   1 
ATOM   3923 C CB  . PHE B 2 289 ? 146.145 144.507 138.793 1.00 61.72  ?  292 PHE B CB  1 
ATOM   3924 C CG  . PHE B 2 289 ? 145.125 145.342 138.060 1.00 61.72  ?  292 PHE B CG  1 
ATOM   3925 C CD1 . PHE B 2 289 ? 144.197 146.109 138.745 1.00 61.72  ?  292 PHE B CD1 1 
ATOM   3926 C CD2 . PHE B 2 289 ? 145.096 145.352 136.677 1.00 61.72  ?  292 PHE B CD2 1 
ATOM   3927 C CE1 . PHE B 2 289 ? 143.268 146.870 138.066 1.00 61.72  ?  292 PHE B CE1 1 
ATOM   3928 C CE2 . PHE B 2 289 ? 144.168 146.111 135.992 1.00 61.72  ?  292 PHE B CE2 1 
ATOM   3929 C CZ  . PHE B 2 289 ? 143.253 146.870 136.688 1.00 61.72  ?  292 PHE B CZ  1 
ATOM   3930 N N   . ASN B 2 290 ? 148.263 144.360 141.610 1.00 62.23  ?  293 ASN B N   1 
ATOM   3931 C CA  . ASN B 2 290 ? 149.361 143.559 142.119 1.00 62.23  ?  293 ASN B CA  1 
ATOM   3932 C C   . ASN B 2 290 ? 149.199 143.317 143.618 1.00 62.23  ?  293 ASN B C   1 
ATOM   3933 O O   . ASN B 2 290 ? 148.189 143.677 144.230 1.00 62.23  ?  293 ASN B O   1 
ATOM   3934 C CB  . ASN B 2 290 ? 150.692 144.243 141.805 1.00 62.23  ?  293 ASN B CB  1 
ATOM   3935 C CG  . ASN B 2 290 ? 151.179 143.952 140.401 1.00 62.23  ?  293 ASN B CG  1 
ATOM   3936 O OD1 . ASN B 2 290 ? 150.476 143.333 139.603 1.00 62.23  ?  293 ASN B OD1 1 
ATOM   3937 N ND2 . ASN B 2 290 ? 152.390 144.399 140.091 1.00 62.23  ?  293 ASN B ND2 1 
ATOM   3938 N N   . CYS B 2 291 ? 150.211 142.695 144.218 1.00 58.37  ?  294 CYS B N   1 
ATOM   3939 C CA  . CYS B 2 291 ? 150.242 142.446 145.656 1.00 58.37  ?  294 CYS B CA  1 
ATOM   3940 C C   . CYS B 2 291 ? 151.706 142.354 146.059 1.00 58.37  ?  294 CYS B C   1 
ATOM   3941 O O   . CYS B 2 291 ? 152.406 141.428 145.642 1.00 58.37  ?  294 CYS B O   1 
ATOM   3942 C CB  . CYS B 2 291 ? 149.487 141.171 146.017 1.00 58.37  ?  294 CYS B CB  1 
ATOM   3943 S SG  . CYS B 2 291 ? 149.710 140.630 147.726 1.00 58.37  ?  294 CYS B SG  1 
ATOM   3944 N N   . ASN B 2 292 ? 152.166 143.308 146.859 1.00 60.03  ?  295 ASN B N   1 
ATOM   3945 C CA  . ASN B 2 292 ? 153.582 143.439 147.172 1.00 60.03  ?  295 ASN B CA  1 
ATOM   3946 C C   . ASN B 2 292 ? 153.902 142.831 148.529 1.00 60.03  ?  295 ASN B C   1 
ATOM   3947 O O   . ASN B 2 292 ? 153.159 143.011 149.498 1.00 60.03  ?  295 ASN B O   1 
ATOM   3948 C CB  . ASN B 2 292 ? 154.010 144.907 147.149 1.00 60.03  ?  295 ASN B CB  1 
ATOM   3949 C CG  . ASN B 2 292 ? 153.884 145.525 145.774 1.00 60.03  ?  295 ASN B CG  1 
ATOM   3950 O OD1 . ASN B 2 292 ? 153.774 144.821 144.772 1.00 60.03  ?  295 ASN B OD1 1 
ATOM   3951 N ND2 . ASN B 2 292 ? 153.901 146.850 145.717 1.00 60.03  ?  295 ASN B ND2 1 
ATOM   3952 N N   . VAL B 2 293 ? 155.020 142.113 148.589 1.00 59.75  ?  296 VAL B N   1 
ATOM   3953 C CA  . VAL B 2 293 ? 155.542 141.534 149.819 1.00 59.75  ?  296 VAL B CA  1 
ATOM   3954 C C   . VAL B 2 293 ? 156.768 142.340 150.215 1.00 59.75  ?  296 VAL B C   1 
ATOM   3955 O O   . VAL B 2 293 ? 157.774 142.344 149.493 1.00 59.75  ?  296 VAL B O   1 
ATOM   3956 C CB  . VAL B 2 293 ? 155.895 140.050 149.641 1.00 59.75  ?  296 VAL B CB  1 
ATOM   3957 C CG1 . VAL B 2 293 ? 156.361 139.452 150.957 1.00 59.75  ?  296 VAL B CG1 1 
ATOM   3958 C CG2 . VAL B 2 293 ? 154.707 139.287 149.089 1.00 59.75  ?  296 VAL B CG2 1 
ATOM   3959 N N   . TRP B 2 294 ? 156.679 143.019 151.356 1.00 60.67  ?  297 TRP B N   1 
ATOM   3960 C CA  . TRP B 2 294 ? 157.732 143.869 151.885 1.00 60.67  ?  297 TRP B CA  1 
ATOM   3961 C C   . TRP B 2 294 ? 158.466 143.167 153.018 1.00 60.67  ?  297 TRP B C   1 
ATOM   3962 O O   . TRP B 2 294 ? 157.883 142.380 153.768 1.00 60.67  ?  297 TRP B O   1 
ATOM   3963 C CB  . TRP B 2 294 ? 157.161 145.188 152.412 1.00 60.67  ?  297 TRP B CB  1 
ATOM   3964 C CG  . TRP B 2 294 ? 156.339 145.959 151.435 1.00 60.67  ?  297 TRP B CG  1 
ATOM   3965 C CD1 . TRP B 2 294 ? 155.026 145.760 151.132 1.00 60.67  ?  297 TRP B CD1 1 
ATOM   3966 C CD2 . TRP B 2 294 ? 156.767 147.079 150.654 1.00 60.67  ?  297 TRP B CD2 1 
ATOM   3967 N NE1 . TRP B 2 294 ? 154.613 146.677 150.197 1.00 60.67  ?  297 TRP B NE1 1 
ATOM   3968 C CE2 . TRP B 2 294 ? 155.664 147.498 149.888 1.00 60.67  ?  297 TRP B CE2 1 
ATOM   3969 C CE3 . TRP B 2 294 ? 157.979 147.761 150.523 1.00 60.67  ?  297 TRP B CE3 1 
ATOM   3970 C CZ2 . TRP B 2 294 ? 155.736 148.569 149.003 1.00 60.67  ?  297 TRP B CZ2 1 
ATOM   3971 C CZ3 . TRP B 2 294 ? 158.048 148.823 149.645 1.00 60.67  ?  297 TRP B CZ3 1 
ATOM   3972 C CH2 . TRP B 2 294 ? 156.935 149.217 148.896 1.00 60.67  ?  297 TRP B CH2 1 
ATOM   3973 N N   . ASP B 2 295 ? 159.753 143.470 153.140 1.00 65.76  ?  298 ASP B N   1 
ATOM   3974 C CA  . ASP B 2 295 ? 160.523 143.092 154.321 1.00 65.76  ?  298 ASP B CA  1 
ATOM   3975 C C   . ASP B 2 295 ? 160.094 144.001 155.464 1.00 65.76  ?  298 ASP B C   1 
ATOM   3976 O O   . ASP B 2 295 ? 160.474 145.172 155.517 1.00 65.76  ?  298 ASP B O   1 
ATOM   3977 C CB  . ASP B 2 295 ? 162.017 143.212 154.046 1.00 65.76  ?  298 ASP B CB  1 
ATOM   3978 C CG  . ASP B 2 295 ? 162.857 142.409 155.018 1.00 65.76  ?  298 ASP B CG  1 
ATOM   3979 O OD1 . ASP B 2 295 ? 162.369 142.109 156.127 1.00 65.76  ?  298 ASP B OD1 1 
ATOM   3980 O OD2 . ASP B 2 295 ? 164.011 142.081 154.675 1.00 65.76  -1 298 ASP B OD2 1 
ATOM   3981 N N   . ALA B 2 296 ? 159.288 143.465 156.384 1.00 64.17  ?  299 ALA B N   1 
ATOM   3982 C CA  . ALA B 2 296 ? 158.712 144.283 157.444 1.00 64.17  ?  299 ALA B CA  1 
ATOM   3983 C C   . ALA B 2 296 ? 159.768 144.905 158.346 1.00 64.17  ?  299 ALA B C   1 
ATOM   3984 O O   . ALA B 2 296 ? 159.486 145.909 159.008 1.00 64.17  ?  299 ALA B O   1 
ATOM   3985 C CB  . ALA B 2 296 ? 157.741 143.451 158.282 1.00 64.17  ?  299 ALA B CB  1 
ATOM   3986 N N   . LEU B 2 297 ? 160.970 144.337 158.392 1.00 70.46  ?  300 LEU B N   1 
ATOM   3987 C CA  . LEU B 2 297 ? 162.045 144.861 159.221 1.00 70.46  ?  300 LEU B CA  1 
ATOM   3988 C C   . LEU B 2 297 ? 163.012 145.755 158.456 1.00 70.46  ?  300 LEU B C   1 
ATOM   3989 O O   . LEU B 2 297 ? 163.917 146.327 159.069 1.00 70.46  ?  300 LEU B O   1 
ATOM   3990 C CB  . LEU B 2 297 ? 162.816 143.708 159.869 1.00 70.46  ?  300 LEU B CB  1 
ATOM   3991 C CG  . LEU B 2 297 ? 162.077 142.916 160.948 1.00 70.46  ?  300 LEU B CG  1 
ATOM   3992 C CD1 . LEU B 2 297 ? 163.046 142.043 161.725 1.00 70.46  ?  300 LEU B CD1 1 
ATOM   3993 C CD2 . LEU B 2 297 ? 161.328 143.851 161.882 1.00 70.46  ?  300 LEU B CD2 1 
ATOM   3994 N N   . LYS B 2 298 ? 162.849 145.891 157.138 1.00 70.79  ?  301 LYS B N   1 
ATOM   3995 C CA  . LYS B 2 298 ? 163.783 146.666 156.332 1.00 70.79  ?  301 LYS B CA  1 
ATOM   3996 C C   . LYS B 2 298 ? 163.126 147.612 155.337 1.00 70.79  ?  301 LYS B C   1 
ATOM   3997 O O   . LYS B 2 298 ? 163.848 148.378 154.688 1.00 70.79  ?  301 LYS B O   1 
ATOM   3998 C CB  . LYS B 2 298 ? 164.733 145.731 155.566 1.00 70.79  ?  301 LYS B CB  1 
ATOM   3999 C CG  . LYS B 2 298 ? 165.649 144.910 156.457 1.00 70.79  ?  301 LYS B CG  1 
ATOM   4000 C CD  . LYS B 2 298 ? 166.745 144.234 155.654 1.00 70.79  ?  301 LYS B CD  1 
ATOM   4001 C CE  . LYS B 2 298 ? 167.960 145.134 155.518 1.00 70.79  ?  301 LYS B CE  1 
ATOM   4002 N NZ  . LYS B 2 298 ? 168.713 145.244 156.796 1.00 70.79  1  301 LYS B NZ  1 
ATOM   4003 N N   . ALA B 2 299 ? 161.799 147.586 155.193 1.00 68.97  ?  302 ALA B N   1 
ATOM   4004 C CA  . ALA B 2 299 ? 161.081 148.449 154.251 1.00 68.97  ?  302 ALA B CA  1 
ATOM   4005 C C   . ALA B 2 299 ? 161.585 148.264 152.822 1.00 68.97  ?  302 ALA B C   1 
ATOM   4006 O O   . ALA B 2 299 ? 161.697 149.221 152.054 1.00 68.97  ?  302 ALA B O   1 
ATOM   4007 C CB  . ALA B 2 299 ? 161.162 149.920 154.663 1.00 68.97  ?  302 ALA B CB  1 
ATOM   4008 N N   . ASP B 2 300 ? 161.893 147.023 152.462 1.00 71.16  ?  303 ASP B N   1 
ATOM   4009 C CA  . ASP B 2 300 ? 162.334 146.676 151.119 1.00 71.16  ?  303 ASP B CA  1 
ATOM   4010 C C   . ASP B 2 300 ? 161.306 145.753 150.483 1.00 71.16  ?  303 ASP B C   1 
ATOM   4011 O O   . ASP B 2 300 ? 160.866 144.785 151.110 1.00 71.16  ?  303 ASP B O   1 
ATOM   4012 C CB  . ASP B 2 300 ? 163.707 146.001 151.147 1.00 71.16  ?  303 ASP B CB  1 
ATOM   4013 C CG  . ASP B 2 300 ? 164.831 146.978 151.424 1.00 71.16  ?  303 ASP B CG  1 
ATOM   4014 O OD1 . ASP B 2 300 ? 164.670 148.177 151.112 1.00 71.16  ?  303 ASP B OD1 1 
ATOM   4015 O OD2 . ASP B 2 300 ? 165.878 146.548 151.952 1.00 71.16  -1 303 ASP B OD2 1 
ATOM   4016 N N   . ARG B 2 301 ? 160.923 146.055 149.247 1.00 69.54  ?  304 ARG B N   1 
ATOM   4017 C CA  . ARG B 2 301 ? 159.952 145.232 148.531 1.00 69.54  ?  304 ARG B CA  1 
ATOM   4018 C C   . ARG B 2 301 ? 160.606 143.903 148.185 1.00 69.54  ?  304 ARG B C   1 
ATOM   4019 O O   . ARG B 2 301 ? 161.405 143.811 147.252 1.00 69.54  ?  304 ARG B O   1 
ATOM   4020 C CB  . ARG B 2 301 ? 159.456 145.947 147.281 1.00 69.54  ?  304 ARG B CB  1 
ATOM   4021 C CG  . ARG B 2 301 ? 158.096 145.467 146.806 1.00 69.54  ?  304 ARG B CG  1 
ATOM   4022 C CD  . ARG B 2 301 ? 157.865 145.797 145.343 1.00 69.54  ?  304 ARG B CD  1 
ATOM   4023 N NE  . ARG B 2 301 ? 158.065 147.212 145.062 1.00 69.54  ?  304 ARG B NE  1 
ATOM   4024 C CZ  . ARG B 2 301 ? 157.756 147.797 143.913 1.00 69.54  ?  304 ARG B CZ  1 
ATOM   4025 N NH1 . ARG B 2 301 ? 157.223 147.116 142.913 1.00 69.54  1  304 ARG B NH1 1 
ATOM   4026 N NH2 . ARG B 2 301 ? 157.988 149.098 143.765 1.00 69.54  ?  304 ARG B NH2 1 
ATOM   4027 N N   . ALA B 2 302 ? 160.269 142.861 148.946 1.00 68.52  ?  305 ALA B N   1 
ATOM   4028 C CA  . ALA B 2 302 ? 160.873 141.554 148.726 1.00 68.52  ?  305 ALA B CA  1 
ATOM   4029 C C   . ALA B 2 302 ? 160.327 140.870 147.481 1.00 68.52  ?  305 ALA B C   1 
ATOM   4030 O O   . ALA B 2 302 ? 161.068 140.150 146.803 1.00 68.52  ?  305 ALA B O   1 
ATOM   4031 C CB  . ALA B 2 302 ? 160.660 140.662 149.948 1.00 68.52  ?  305 ALA B CB  1 
ATOM   4032 N N   . GLY B 2 303 ? 159.054 141.074 147.162 1.00 65.11  ?  306 GLY B N   1 
ATOM   4033 C CA  . GLY B 2 303 ? 158.488 140.399 146.006 1.00 65.11  ?  306 GLY B CA  1 
ATOM   4034 C C   . GLY B 2 303 ? 157.193 141.037 145.562 1.00 65.11  ?  306 GLY B C   1 
ATOM   4035 O O   . GLY B 2 303 ? 156.643 141.916 146.229 1.00 65.11  ?  306 GLY B O   1 
ATOM   4036 N N   . VAL B 2 304 ? 156.703 140.566 144.417 1.00 58.73  ?  307 VAL B N   1 
ATOM   4037 C CA  . VAL B 2 304 ? 155.452 141.037 143.835 1.00 58.73  ?  307 VAL B CA  1 
ATOM   4038 C C   . VAL B 2 304 ? 154.596 139.827 143.489 1.00 58.73  ?  307 VAL B C   1 
ATOM   4039 O O   . VAL B 2 304 ? 155.059 138.910 142.802 1.00 58.73  ?  307 VAL B O   1 
ATOM   4040 C CB  . VAL B 2 304 ? 155.694 141.902 142.583 1.00 58.73  ?  307 VAL B CB  1 
ATOM   4041 C CG1 . VAL B 2 304 ? 154.379 142.214 141.891 1.00 58.73  ?  307 VAL B CG1 1 
ATOM   4042 C CG2 . VAL B 2 304 ? 156.423 143.183 142.954 1.00 58.73  ?  307 VAL B CG2 1 
ATOM   4043 N N   . LEU B 2 305 ? 153.353 139.824 143.965 1.00 56.07  ?  308 LEU B N   1 
ATOM   4044 C CA  . LEU B 2 305 ? 152.405 138.754 143.658 1.00 56.07  ?  308 LEU B CA  1 
ATOM   4045 C C   . LEU B 2 305 ? 151.480 139.191 142.523 1.00 56.07  ?  308 LEU B C   1 
ATOM   4046 O O   . LEU B 2 305 ? 150.273 139.370 142.688 1.00 56.07  ?  308 LEU B O   1 
ATOM   4047 C CB  . LEU B 2 305 ? 151.619 138.366 144.906 1.00 56.07  ?  308 LEU B CB  1 
ATOM   4048 C CG  . LEU B 2 305 ? 152.097 137.143 145.688 1.00 56.07  ?  308 LEU B CG  1 
ATOM   4049 C CD1 . LEU B 2 305 ? 153.503 137.351 146.216 1.00 56.07  ?  308 LEU B CD1 1 
ATOM   4050 C CD2 . LEU B 2 305 ? 151.138 136.843 146.826 1.00 56.07  ?  308 LEU B CD2 1 
ATOM   4051 N N   . ALA B 2 306 ? 152.040 139.331 141.343 1.00 58.29  ?  309 ALA B N   1 
ATOM   4052 C CA  . ALA B 2 306 ? 151.238 139.725 140.208 1.00 58.29  ?  309 ALA B CA  1 
ATOM   4053 C C   . ALA B 2 306 ? 150.422 139.001 139.188 1.00 58.29  ?  309 ALA B C   1 
ATOM   4054 O O   . ALA B 2 306 ? 150.688 139.095 138.002 1.00 58.29  ?  309 ALA B O   1 
ATOM   4055 C CB  . ALA B 2 306 ? 152.105 140.399 139.182 1.00 58.29  ?  309 ALA B CB  1 
ATOM   4056 N N   . GLY B 2 307 ? 149.423 138.273 139.646 1.00 56.08  ?  310 GLY B N   1 
ATOM   4057 C CA  . GLY B 2 307 ? 148.587 137.532 138.740 1.00 56.08  ?  310 GLY B CA  1 
ATOM   4058 C C   . GLY B 2 307 ? 147.237 138.047 138.346 1.00 56.08  ?  310 GLY B C   1 
ATOM   4059 O O   . GLY B 2 307 ? 146.881 138.045 137.179 1.00 56.08  ?  310 GLY B O   1 
ATOM   4060 N N   . HIS B 2 308 ? 146.568 138.623 139.342 1.00 56.04  ?  311 HIS B N   1 
ATOM   4061 C CA  . HIS B 2 308 ? 145.291 139.259 139.127 1.00 56.04  ?  311 HIS B CA  1 
ATOM   4062 C C   . HIS B 2 308 ? 144.992 140.305 138.076 1.00 56.04  ?  311 HIS B C   1 
ATOM   4063 O O   . HIS B 2 308 ? 145.822 141.164 137.821 1.00 56.04  ?  311 HIS B O   1 
ATOM   4064 C CB  . HIS B 2 308 ? 145.057 139.765 140.535 1.00 56.04  ?  311 HIS B CB  1 
ATOM   4065 C CG  . HIS B 2 308 ? 144.533 138.721 141.467 1.00 56.04  ?  311 HIS B CG  1 
ATOM   4066 N ND1 . HIS B 2 308 ? 143.609 137.777 141.078 1.00 56.04  ?  311 HIS B ND1 1 
ATOM   4067 C CD2 . HIS B 2 308 ? 144.807 138.467 142.766 1.00 56.04  ?  311 HIS B CD2 1 
ATOM   4068 C CE1 . HIS B 2 308 ? 143.334 136.988 142.099 1.00 56.04  ?  311 HIS B CE1 1 
ATOM   4069 N NE2 . HIS B 2 308 ? 144.048 137.385 143.135 1.00 56.04  ?  311 HIS B NE2 1 
ATOM   4070 N N   . ASP B 2 309 ? 143.837 140.253 137.458 1.00 60.36  ?  312 ASP B N   1 
ATOM   4071 C CA  . ASP B 2 309 ? 143.423 141.115 136.359 1.00 60.36  ?  312 ASP B CA  1 
ATOM   4072 C C   . ASP B 2 309 ? 142.623 142.328 136.815 1.00 60.36  ?  312 ASP B C   1 
ATOM   4073 O O   . ASP B 2 309 ? 142.204 143.125 135.970 1.00 60.36  ?  312 ASP B O   1 
ATOM   4074 C CB  . ASP B 2 309 ? 142.603 140.315 135.343 1.00 60.36  ?  312 ASP B CB  1 
ATOM   4075 N N   . ASN B 2 310 ? 142.400 142.490 138.115 1.00 59.53  ?  313 ASN B N   1 
ATOM   4076 C CA  . ASN B 2 310 ? 141.664 143.635 138.634 1.00 59.53  ?  313 ASN B CA  1 
ATOM   4077 C C   . ASN B 2 310 ? 142.185 143.944 140.034 1.00 59.53  ?  313 ASN B C   1 
ATOM   4078 O O   . ASN B 2 310 ? 143.148 143.330 140.504 1.00 59.53  ?  313 ASN B O   1 
ATOM   4079 C CB  . ASN B 2 310 ? 140.155 143.366 138.615 1.00 59.53  ?  313 ASN B CB  1 
ATOM   4080 C CG  . ASN B 2 310 ? 139.345 144.619 138.357 1.00 59.53  ?  313 ASN B CG  1 
ATOM   4081 O OD1 . ASN B 2 310 ? 139.783 145.727 138.663 1.00 59.53  ?  313 ASN B OD1 1 
ATOM   4082 N ND2 . ASN B 2 310 ? 138.158 144.450 137.790 1.00 59.53  ?  313 ASN B ND2 1 
ATOM   4083 N N   . ARG B 2 311 ? 141.553 144.913 140.694 1.00 59.24  ?  314 ARG B N   1 
ATOM   4084 C CA  . ARG B 2 311 ? 142.009 145.351 142.007 1.00 59.24  ?  314 ARG B CA  1 
ATOM   4085 C C   . ARG B 2 311 ? 141.977 144.201 143.003 1.00 59.24  ?  314 ARG B C   1 
ATOM   4086 O O   . ARG B 2 311 ? 140.950 143.541 143.172 1.00 59.24  ?  314 ARG B O   1 
ATOM   4087 C CB  . ARG B 2 311 ? 141.132 146.496 142.514 1.00 59.24  ?  314 ARG B CB  1 
ATOM   4088 C CG  . ARG B 2 311 ? 141.607 147.881 142.121 1.00 59.24  ?  314 ARG B CG  1 
ATOM   4089 C CD  . ARG B 2 311 ? 140.505 148.908 142.317 1.00 59.24  ?  314 ARG B CD  1 
ATOM   4090 N NE  . ARG B 2 311 ? 140.082 148.990 143.710 1.00 59.24  ?  314 ARG B NE  1 
ATOM   4091 C CZ  . ARG B 2 311 ? 139.796 150.120 144.341 1.00 59.24  ?  314 ARG B CZ  1 
ATOM   4092 N NH1 . ARG B 2 311 ? 139.879 151.292 143.733 1.00 59.24  1  314 ARG B NH1 1 
ATOM   4093 N NH2 . ARG B 2 311 ? 139.417 150.074 145.615 1.00 59.24  ?  314 ARG B NH2 1 
ATOM   4094 N N   . VAL B 2 312 ? 143.103 143.976 143.678 1.00 54.66  ?  315 VAL B N   1 
ATOM   4095 C CA  . VAL B 2 312 ? 143.174 142.972 144.732 1.00 54.66  ?  315 VAL B CA  1 
ATOM   4096 C C   . VAL B 2 312 ? 142.434 143.520 145.944 1.00 54.66  ?  315 VAL B C   1 
ATOM   4097 O O   . VAL B 2 312 ? 142.944 144.391 146.655 1.00 54.66  ?  315 VAL B O   1 
ATOM   4098 C CB  . VAL B 2 312 ? 144.630 142.613 145.078 1.00 54.66  ?  315 VAL B CB  1 
ATOM   4099 C CG1 . VAL B 2 312 ? 144.680 141.722 146.307 1.00 54.66  ?  315 VAL B CG1 1 
ATOM   4100 C CG2 . VAL B 2 312 ? 145.300 141.934 143.899 1.00 54.66  ?  315 VAL B CG2 1 
ATOM   4101 N N   . SER B 2 313 ? 141.225 143.016 146.182 1.00 53.21  ?  316 SER B N   1 
ATOM   4102 C CA  . SER B 2 313 ? 140.356 143.588 147.201 1.00 53.21  ?  316 SER B CA  1 
ATOM   4103 C C   . SER B 2 313 ? 140.555 142.973 148.577 1.00 53.21  ?  316 SER B C   1 
ATOM   4104 O O   . SER B 2 313 ? 140.320 143.649 149.585 1.00 53.21  ?  316 SER B O   1 
ATOM   4105 C CB  . SER B 2 313 ? 138.891 143.432 146.787 1.00 53.21  ?  316 SER B CB  1 
ATOM   4106 O OG  . SER B 2 313 ? 138.569 142.070 146.575 1.00 53.21  ?  316 SER B OG  1 
ATOM   4107 N N   . CYS B 2 314 ? 140.976 141.713 148.654 1.00 53.30  ?  317 CYS B N   1 
ATOM   4108 C CA  . CYS B 2 314 ? 141.106 141.040 149.937 1.00 53.30  ?  317 CYS B CA  1 
ATOM   4109 C C   . CYS B 2 314 ? 142.345 140.159 149.945 1.00 53.30  ?  317 CYS B C   1 
ATOM   4110 O O   . CYS B 2 314 ? 142.765 139.639 148.910 1.00 53.30  ?  317 CYS B O   1 
ATOM   4111 C CB  . CYS B 2 314 ? 139.853 140.218 150.251 1.00 53.30  ?  317 CYS B CB  1 
ATOM   4112 S SG  . CYS B 2 314 ? 139.566 138.862 149.108 1.00 53.30  ?  317 CYS B SG  1 
ATOM   4113 N N   . LEU B 2 315 ? 142.913 139.983 151.135 1.00 50.98  ?  318 LEU B N   1 
ATOM   4114 C CA  . LEU B 2 315 ? 144.167 139.268 151.309 1.00 50.98  ?  318 LEU B CA  1 
ATOM   4115 C C   . LEU B 2 315 ? 144.134 138.536 152.641 1.00 50.98  ?  318 LEU B C   1 
ATOM   4116 O O   . LEU B 2 315 ? 143.574 139.043 153.617 1.00 50.98  ?  318 LEU B O   1 
ATOM   4117 C CB  . LEU B 2 315 ? 145.355 140.234 151.263 1.00 50.98  ?  318 LEU B CB  1 
ATOM   4118 C CG  . LEU B 2 315 ? 146.765 139.688 151.456 1.00 50.98  ?  318 LEU B CG  1 
ATOM   4119 C CD1 . LEU B 2 315 ? 147.217 138.950 150.222 1.00 50.98  ?  318 LEU B CD1 1 
ATOM   4120 C CD2 . LEU B 2 315 ? 147.712 140.821 151.775 1.00 50.98  ?  318 LEU B CD2 1 
ATOM   4121 N N   . GLY B 2 316 ? 144.732 137.349 152.680 1.00 49.90  ?  319 GLY B N   1 
ATOM   4122 C CA  . GLY B 2 316 ? 144.768 136.583 153.910 1.00 49.90  ?  319 GLY B CA  1 
ATOM   4123 C C   . GLY B 2 316 ? 145.920 135.609 153.920 1.00 49.90  ?  319 GLY B C   1 
ATOM   4124 O O   . GLY B 2 316 ? 146.389 135.165 152.869 1.00 49.90  ?  319 GLY B O   1 
ATOM   4125 N N   . VAL B 2 317 ? 146.381 135.276 155.123 1.00 51.78  ?  320 VAL B N   1 
ATOM   4126 C CA  . VAL B 2 317 ? 147.448 134.305 155.329 1.00 51.78  ?  320 VAL B CA  1 
ATOM   4127 C C   . VAL B 2 317 ? 146.956 133.260 156.318 1.00 51.78  ?  320 VAL B C   1 
ATOM   4128 O O   . VAL B 2 317 ? 146.347 133.598 157.339 1.00 51.78  ?  320 VAL B O   1 
ATOM   4129 C CB  . VAL B 2 317 ? 148.744 134.972 155.837 1.00 51.78  ?  320 VAL B CB  1 
ATOM   4130 C CG1 . VAL B 2 317 ? 149.824 133.931 156.066 1.00 51.78  ?  320 VAL B CG1 1 
ATOM   4131 C CG2 . VAL B 2 317 ? 149.223 136.018 154.850 1.00 51.78  ?  320 VAL B CG2 1 
ATOM   4132 N N   . THR B 2 318 ? 147.212 131.991 156.012 1.00 58.68  ?  321 THR B N   1 
ATOM   4133 C CA  . THR B 2 318 ? 146.776 130.904 156.873 1.00 58.68  ?  321 THR B CA  1 
ATOM   4134 C C   . THR B 2 318 ? 147.485 130.967 158.223 1.00 58.68  ?  321 THR B C   1 
ATOM   4135 O O   . THR B 2 318 ? 148.569 131.541 158.362 1.00 58.68  ?  321 THR B O   1 
ATOM   4136 C CB  . THR B 2 318 ? 147.040 129.553 156.211 1.00 58.68  ?  321 THR B CB  1 
ATOM   4137 O OG1 . THR B 2 318 ? 148.442 129.263 156.260 1.00 58.68  ?  321 THR B OG1 1 
ATOM   4138 C CG2 . THR B 2 318 ? 146.592 129.572 154.764 1.00 58.68  ?  321 THR B CG2 1 
ATOM   4139 N N   . ASP B 2 319 ? 146.849 130.367 159.233 1.00 66.66  ?  322 ASP B N   1 
ATOM   4140 C CA  . ASP B 2 319 ? 147.403 130.409 160.582 1.00 66.66  ?  322 ASP B CA  1 
ATOM   4141 C C   . ASP B 2 319 ? 148.718 129.647 160.683 1.00 66.66  ?  322 ASP B C   1 
ATOM   4142 O O   . ASP B 2 319 ? 149.567 129.994 161.511 1.00 66.66  ?  322 ASP B O   1 
ATOM   4143 C CB  . ASP B 2 319 ? 146.392 129.860 161.587 1.00 66.66  ?  322 ASP B CB  1 
ATOM   4144 C CG  . ASP B 2 319 ? 145.194 130.769 161.758 1.00 66.66  ?  322 ASP B CG  1 
ATOM   4145 O OD1 . ASP B 2 319 ? 145.348 131.995 161.582 1.00 66.66  ?  322 ASP B OD1 1 
ATOM   4146 O OD2 . ASP B 2 319 ? 144.099 130.261 162.074 1.00 66.66  -1 322 ASP B OD2 1 
ATOM   4147 N N   . ASP B 2 320 ? 148.908 128.616 159.863 1.00 67.28  ?  323 ASP B N   1 
ATOM   4148 C CA  . ASP B 2 320 ? 150.187 127.920 159.827 1.00 67.28  ?  323 ASP B CA  1 
ATOM   4149 C C   . ASP B 2 320 ? 151.190 128.588 158.897 1.00 67.28  ?  323 ASP B C   1 
ATOM   4150 O O   . ASP B 2 320 ? 152.323 128.107 158.787 1.00 67.28  ?  323 ASP B O   1 
ATOM   4151 C CB  . ASP B 2 320 ? 149.989 126.456 159.421 1.00 67.28  ?  323 ASP B CB  1 
ATOM   4152 C CG  . ASP B 2 320 ? 149.245 126.305 158.110 1.00 67.28  ?  323 ASP B CG  1 
ATOM   4153 O OD1 . ASP B 2 320 ? 148.904 127.333 157.493 1.00 67.28  ?  323 ASP B OD1 1 
ATOM   4154 O OD2 . ASP B 2 320 ? 148.999 125.154 157.695 1.00 67.28  -1 323 ASP B OD2 1 
ATOM   4155 N N   . GLY B 2 321 ? 150.803 129.670 158.225 1.00 67.58  ?  324 GLY B N   1 
ATOM   4156 C CA  . GLY B 2 321 ? 151.712 130.401 157.367 1.00 67.58  ?  324 GLY B CA  1 
ATOM   4157 C C   . GLY B 2 321 ? 152.115 129.685 156.102 1.00 67.58  ?  324 GLY B C   1 
ATOM   4158 O O   . GLY B 2 321 ? 153.132 130.045 155.503 1.00 67.58  ?  324 GLY B O   1 
ATOM   4159 N N   . MET B 2 322 ? 151.349 128.685 155.670 1.00 68.43  ?  325 MET B N   1 
ATOM   4160 C CA  . MET B 2 322 ? 151.746 127.880 154.524 1.00 68.43  ?  325 MET B CA  1 
ATOM   4161 C C   . MET B 2 322 ? 151.338 128.494 153.192 1.00 68.43  ?  325 MET B C   1 
ATOM   4162 O O   . MET B 2 322 ? 151.967 128.195 152.173 1.00 68.43  ?  325 MET B O   1 
ATOM   4163 C CB  . MET B 2 322 ? 151.156 126.474 154.647 1.00 68.43  ?  325 MET B CB  1 
ATOM   4164 C CG  . MET B 2 322 ? 151.771 125.455 153.704 1.00 68.43  ?  325 MET B CG  1 
ATOM   4165 S SD  . MET B 2 322 ? 153.286 124.730 154.359 1.00 68.43  ?  325 MET B SD  1 
ATOM   4166 C CE  . MET B 2 322 ? 152.798 124.398 156.049 1.00 68.43  ?  325 MET B CE  1 
ATOM   4167 N N   . ALA B 2 323 ? 150.316 129.347 153.168 1.00 58.13  ?  326 ALA B N   1 
ATOM   4168 C CA  . ALA B 2 323 ? 149.820 129.875 151.907 1.00 58.13  ?  326 ALA B CA  1 
ATOM   4169 C C   . ALA B 2 323 ? 149.229 131.258 152.124 1.00 58.13  ?  326 ALA B C   1 
ATOM   4170 O O   . ALA B 2 323 ? 148.889 131.644 153.245 1.00 58.13  ?  326 ALA B O   1 
ATOM   4171 C CB  . ALA B 2 323 ? 148.775 128.944 151.286 1.00 58.13  ?  326 ALA B CB  1 
ATOM   4172 N N   . VAL B 2 324 ? 149.111 132.003 151.027 1.00 53.08  ?  327 VAL B N   1 
ATOM   4173 C CA  . VAL B 2 324 ? 148.526 133.339 151.030 1.00 53.08  ?  327 VAL B CA  1 
ATOM   4174 C C   . VAL B 2 324 ? 147.428 133.373 149.980 1.00 53.08  ?  327 VAL B C   1 
ATOM   4175 O O   . VAL B 2 324 ? 147.688 133.113 148.803 1.00 53.08  ?  327 VAL B O   1 
ATOM   4176 C CB  . VAL B 2 324 ? 149.572 134.427 150.740 1.00 53.08  ?  327 VAL B CB  1 
ATOM   4177 C CG1 . VAL B 2 324 ? 148.895 135.768 150.561 1.00 53.08  ?  327 VAL B CG1 1 
ATOM   4178 C CG2 . VAL B 2 324 ? 150.596 134.487 151.851 1.00 53.08  ?  327 VAL B CG2 1 
ATOM   4179 N N   . ALA B 2 325 ? 146.212 133.706 150.391 1.00 49.17  ?  328 ALA B N   1 
ATOM   4180 C CA  . ALA B 2 325 ? 145.091 133.793 149.468 1.00 49.17  ?  328 ALA B CA  1 
ATOM   4181 C C   . ALA B 2 325 ? 144.811 135.251 149.134 1.00 49.17  ?  328 ALA B C   1 
ATOM   4182 O O   . ALA B 2 325 ? 144.760 136.102 150.029 1.00 49.17  ?  328 ALA B O   1 
ATOM   4183 C CB  . ALA B 2 325 ? 143.843 133.128 150.048 1.00 49.17  ?  328 ALA B CB  1 
ATOM   4184 N N   . THR B 2 326 ? 144.646 135.531 147.844 1.00 50.71  ?  329 THR B N   1 
ATOM   4185 C CA  . THR B 2 326 ? 144.334 136.863 147.347 1.00 50.71  ?  329 THR B CA  1 
ATOM   4186 C C   . THR B 2 326 ? 143.036 136.799 146.560 1.00 50.71  ?  329 THR B C   1 
ATOM   4187 O O   . THR B 2 326 ? 142.858 135.912 145.719 1.00 50.71  ?  329 THR B O   1 
ATOM   4188 C CB  . THR B 2 326 ? 145.453 137.405 146.452 1.00 50.71  ?  329 THR B CB  1 
ATOM   4189 O OG1 . THR B 2 326 ? 145.475 136.674 145.220 1.00 50.71  ?  329 THR B OG1 1 
ATOM   4190 C CG2 . THR B 2 326 ? 146.800 137.262 147.129 1.00 50.71  ?  329 THR B CG2 1 
ATOM   4191 N N   . GLY B 2 327 ? 142.133 137.734 146.834 1.00 52.50  ?  330 GLY B N   1 
ATOM   4192 C CA  . GLY B 2 327 ? 140.903 137.839 146.080 1.00 52.50  ?  330 GLY B CA  1 
ATOM   4193 C C   . GLY B 2 327 ? 140.760 139.206 145.449 1.00 52.50  ?  330 GLY B C   1 
ATOM   4194 O O   . GLY B 2 327 ? 140.876 140.229 146.133 1.00 52.50  ?  330 GLY B O   1 
ATOM   4195 N N   . SER B 2 328 ? 140.504 139.236 144.147 1.00 55.78  ?  331 SER B N   1 
ATOM   4196 C CA  . SER B 2 328 ? 140.457 140.473 143.389 1.00 55.78  ?  331 SER B CA  1 
ATOM   4197 C C   . SER B 2 328 ? 139.071 140.676 142.794 1.00 55.78  ?  331 SER B C   1 
ATOM   4198 O O   . SER B 2 328 ? 138.186 139.824 142.902 1.00 55.78  ?  331 SER B O   1 
ATOM   4199 C CB  . SER B 2 328 ? 141.517 140.481 142.282 1.00 55.78  ?  331 SER B CB  1 
ATOM   4200 O OG  . SER B 2 328 ? 141.523 139.255 141.576 1.00 55.78  ?  331 SER B OG  1 
ATOM   4201 N N   . TRP B 2 329 ? 138.896 141.833 142.156 1.00 57.31  ?  332 TRP B N   1 
ATOM   4202 C CA  . TRP B 2 329 ? 137.622 142.185 141.545 1.00 57.31  ?  332 TRP B CA  1 
ATOM   4203 C C   . TRP B 2 329 ? 137.336 141.393 140.277 1.00 57.31  ?  332 TRP B C   1 
ATOM   4204 O O   . TRP B 2 329 ? 136.221 141.484 139.752 1.00 57.31  ?  332 TRP B O   1 
ATOM   4205 C CB  . TRP B 2 329 ? 137.589 143.683 141.244 1.00 57.31  ?  332 TRP B CB  1 
ATOM   4206 C CG  . TRP B 2 329 ? 137.320 144.523 142.452 1.00 57.31  ?  332 TRP B CG  1 
ATOM   4207 C CD1 . TRP B 2 329 ? 137.206 144.091 143.739 1.00 57.31  ?  332 TRP B CD1 1 
ATOM   4208 C CD2 . TRP B 2 329 ? 137.139 145.943 142.487 1.00 57.31  ?  332 TRP B CD2 1 
ATOM   4209 N NE1 . TRP B 2 329 ? 136.961 145.152 144.575 1.00 57.31  ?  332 TRP B NE1 1 
ATOM   4210 C CE2 . TRP B 2 329 ? 136.916 146.301 143.830 1.00 57.31  ?  332 TRP B CE2 1 
ATOM   4211 C CE3 . TRP B 2 329 ? 137.142 146.945 141.514 1.00 57.31  ?  332 TRP B CE3 1 
ATOM   4212 C CZ2 . TRP B 2 329 ? 136.698 147.618 144.224 1.00 57.31  ?  332 TRP B CZ2 1 
ATOM   4213 C CZ3 . TRP B 2 329 ? 136.926 148.251 141.907 1.00 57.31  ?  332 TRP B CZ3 1 
ATOM   4214 C CH2 . TRP B 2 329 ? 136.707 148.576 143.250 1.00 57.31  ?  332 TRP B CH2 1 
ATOM   4215 N N   . ASP B 2 330 ? 138.303 140.630 139.772 1.00 57.52  ?  333 ASP B N   1 
ATOM   4216 C CA  . ASP B 2 330 ? 138.089 139.787 138.604 1.00 57.52  ?  333 ASP B CA  1 
ATOM   4217 C C   . ASP B 2 330 ? 137.423 138.460 138.947 1.00 57.52  ?  333 ASP B C   1 
ATOM   4218 O O   . ASP B 2 330 ? 137.419 137.554 138.107 1.00 57.52  ?  333 ASP B O   1 
ATOM   4219 C CB  . ASP B 2 330 ? 139.415 139.536 137.883 1.00 57.52  ?  333 ASP B CB  1 
ATOM   4220 C CG  . ASP B 2 330 ? 140.377 138.702 138.702 1.00 57.52  ?  333 ASP B CG  1 
ATOM   4221 O OD1 . ASP B 2 330 ? 140.226 138.663 139.939 1.00 57.52  ?  333 ASP B OD1 1 
ATOM   4222 O OD2 . ASP B 2 330 ? 141.286 138.086 138.109 1.00 57.52  -1 333 ASP B OD2 1 
ATOM   4223 N N   . SER B 2 331 ? 136.884 138.329 140.162 1.00 56.69  ?  334 SER B N   1 
ATOM   4224 C CA  . SER B 2 331 ? 136.104 137.161 140.579 1.00 56.69  ?  334 SER B CA  1 
ATOM   4225 C C   . SER B 2 331 ? 136.954 135.893 140.625 1.00 56.69  ?  334 SER B C   1 
ATOM   4226 O O   . SER B 2 331 ? 136.484 134.807 140.289 1.00 56.69  ?  334 SER B O   1 
ATOM   4227 C CB  . SER B 2 331 ? 134.885 136.957 139.677 1.00 56.69  ?  334 SER B CB  1 
ATOM   4228 O OG  . SER B 2 331 ? 135.258 136.384 138.436 1.00 56.69  ?  334 SER B OG  1 
ATOM   4229 N N   . PHE B 2 332 ? 138.210 136.024 141.049 1.00 54.48  ?  335 PHE B N   1 
ATOM   4230 C CA  . PHE B 2 332 ? 139.100 134.875 141.149 1.00 54.48  ?  335 PHE B CA  1 
ATOM   4231 C C   . PHE B 2 332 ? 139.871 134.927 142.457 1.00 54.48  ?  335 PHE B C   1 
ATOM   4232 O O   . PHE B 2 332 ? 140.449 135.962 142.801 1.00 54.48  ?  335 PHE B O   1 
ATOM   4233 C CB  . PHE B 2 332 ? 140.075 134.823 139.967 1.00 54.48  ?  335 PHE B CB  1 
ATOM   4234 C CG  . PHE B 2 332 ? 139.429 134.443 138.668 1.00 54.48  ?  335 PHE B CG  1 
ATOM   4235 C CD1 . PHE B 2 332 ? 138.676 133.287 138.568 1.00 54.48  ?  335 PHE B CD1 1 
ATOM   4236 C CD2 . PHE B 2 332 ? 139.572 135.242 137.548 1.00 54.48  ?  335 PHE B CD2 1 
ATOM   4237 C CE1 . PHE B 2 332 ? 138.078 132.935 137.376 1.00 54.48  ?  335 PHE B CE1 1 
ATOM   4238 C CE2 . PHE B 2 332 ? 138.976 134.895 136.354 1.00 54.48  ?  335 PHE B CE2 1 
ATOM   4239 C CZ  . PHE B 2 332 ? 138.229 133.740 136.268 1.00 54.48  ?  335 PHE B CZ  1 
ATOM   4240 N N   . LEU B 2 333 ? 139.873 133.811 143.178 1.00 50.73  ?  336 LEU B N   1 
ATOM   4241 C CA  . LEU B 2 333 ? 140.695 133.632 144.366 1.00 50.73  ?  336 LEU B CA  1 
ATOM   4242 C C   . LEU B 2 333 ? 141.937 132.842 143.983 1.00 50.73  ?  336 LEU B C   1 
ATOM   4243 O O   . LEU B 2 333 ? 141.833 131.794 143.337 1.00 50.73  ?  336 LEU B O   1 
ATOM   4244 C CB  . LEU B 2 333 ? 139.924 132.895 145.460 1.00 50.73  ?  336 LEU B CB  1 
ATOM   4245 C CG  . LEU B 2 333 ? 138.717 133.586 146.090 1.00 50.73  ?  336 LEU B CG  1 
ATOM   4246 C CD1 . LEU B 2 333 ? 138.024 132.633 147.035 1.00 50.73  ?  336 LEU B CD1 1 
ATOM   4247 C CD2 . LEU B 2 333 ? 139.148 134.830 146.832 1.00 50.73  ?  336 LEU B CD2 1 
ATOM   4248 N N   . LYS B 2 334 ? 143.104 133.338 144.376 1.00 50.60  ?  337 LYS B N   1 
ATOM   4249 C CA  . LYS B 2 334 ? 144.368 132.697 144.045 1.00 50.60  ?  337 LYS B CA  1 
ATOM   4250 C C   . LYS B 2 334 ? 145.153 132.421 145.316 1.00 50.60  ?  337 LYS B C   1 
ATOM   4251 O O   . LYS B 2 334 ? 145.371 133.327 146.126 1.00 50.60  ?  337 LYS B O   1 
ATOM   4252 C CB  . LYS B 2 334 ? 145.192 133.563 143.088 1.00 50.60  ?  337 LYS B CB  1 
ATOM   4253 C CG  . LYS B 2 334 ? 144.576 133.706 141.709 1.00 50.60  ?  337 LYS B CG  1 
ATOM   4254 C CD  . LYS B 2 334 ? 145.525 134.397 140.749 1.00 50.60  ?  337 LYS B CD  1 
ATOM   4255 C CE  . LYS B 2 334 ? 145.221 134.016 139.312 1.00 50.60  ?  337 LYS B CE  1 
ATOM   4256 N NZ  . LYS B 2 334 ? 146.460 133.916 138.495 1.00 50.60  1  337 LYS B NZ  1 
ATOM   4257 N N   . ILE B 2 335 ? 145.575 131.172 145.485 1.00 50.80  ?  338 ILE B N   1 
ATOM   4258 C CA  . ILE B 2 335 ? 146.417 130.760 146.601 1.00 50.80  ?  338 ILE B CA  1 
ATOM   4259 C C   . ILE B 2 335 ? 147.859 130.722 146.121 1.00 50.80  ?  338 ILE B C   1 
ATOM   4260 O O   . ILE B 2 335 ? 148.148 130.194 145.041 1.00 50.80  ?  338 ILE B O   1 
ATOM   4261 C CB  . ILE B 2 335 ? 145.979 129.396 147.164 1.00 50.80  ?  338 ILE B CB  1 
ATOM   4262 C CG1 . ILE B 2 335 ? 144.573 129.477 147.766 1.00 50.80  ?  338 ILE B CG1 1 
ATOM   4263 C CG2 . ILE B 2 335 ? 146.968 128.900 148.197 1.00 50.80  ?  338 ILE B CG2 1 
ATOM   4264 C CD1 . ILE B 2 335 ? 143.456 129.195 146.793 1.00 50.80  ?  338 ILE B CD1 1 
ATOM   4265 N N   . TRP B 2 336 ? 148.761 131.297 146.910 1.00 56.24  ?  339 TRP B N   1 
ATOM   4266 C CA  . TRP B 2 336 ? 150.167 131.414 146.568 1.00 56.24  ?  339 TRP B CA  1 
ATOM   4267 C C   . TRP B 2 336 ? 151.006 130.767 147.660 1.00 56.24  ?  339 TRP B C   1 
ATOM   4268 O O   . TRP B 2 336 ? 150.646 130.794 148.842 1.00 56.24  ?  339 TRP B O   1 
ATOM   4269 C CB  . TRP B 2 336 ? 150.584 132.883 146.401 1.00 56.24  ?  339 TRP B CB  1 
ATOM   4270 C CG  . TRP B 2 336 ? 149.628 133.710 145.591 1.00 56.24  ?  339 TRP B CG  1 
ATOM   4271 C CD1 . TRP B 2 336 ? 148.365 134.084 145.944 1.00 56.24  ?  339 TRP B CD1 1 
ATOM   4272 C CD2 . TRP B 2 336 ? 149.865 134.274 144.297 1.00 56.24  ?  339 TRP B CD2 1 
ATOM   4273 N NE1 . TRP B 2 336 ? 147.798 134.838 144.948 1.00 56.24  ?  339 TRP B NE1 1 
ATOM   4274 C CE2 . TRP B 2 336 ? 148.699 134.970 143.926 1.00 56.24  ?  339 TRP B CE2 1 
ATOM   4275 C CE3 . TRP B 2 336 ? 150.948 134.255 143.415 1.00 56.24  ?  339 TRP B CE3 1 
ATOM   4276 C CZ2 . TRP B 2 336 ? 148.585 135.641 142.713 1.00 56.24  ?  339 TRP B CZ2 1 
ATOM   4277 C CZ3 . TRP B 2 336 ? 150.833 134.921 142.212 1.00 56.24  ?  339 TRP B CZ3 1 
ATOM   4278 C CH2 . TRP B 2 336 ? 149.660 135.604 141.872 1.00 56.24  ?  339 TRP B CH2 1 
ATOM   4279 N N   . ASN B 2 337 ? 152.132 130.194 147.253 1.00 67.65  ?  340 ASN B N   1 
ATOM   4280 C CA  . ASN B 2 337 ? 153.015 129.495 148.175 1.00 67.65  ?  340 ASN B CA  1 
ATOM   4281 C C   . ASN B 2 337 ? 154.469 129.625 147.733 1.00 67.65  ?  340 ASN B C   1 
ATOM   4282 O O   . ASN B 2 337 ? 155.385 129.658 148.554 1.00 67.65  ?  340 ASN B O   1 
ATOM   4283 C CB  . ASN B 2 337 ? 152.617 128.023 148.274 1.00 67.65  ?  340 ASN B CB  1 
ATOM   4284 C CG  . ASN B 2 337 ? 153.148 127.357 149.523 1.00 67.65  ?  340 ASN B CG  1 
ATOM   4285 O OD1 . ASN B 2 337 ? 153.988 127.913 150.230 1.00 67.65  ?  340 ASN B OD1 1 
ATOM   4286 N ND2 . ASN B 2 337 ? 152.652 126.161 149.809 1.00 67.65  ?  340 ASN B ND2 1 
ATOM   4287 O OXT . ASN B 2 337 ? 154.762 129.704 146.541 1.00 67.65  -1 340 ASN B OXT 1 
ATOM   4288 N N   . SER C 3 1   ? 129.295 169.918 171.138 1.00 129.63 ?  8   SER G N   1 
ATOM   4289 C CA  . SER C 3 1   ? 129.354 171.179 171.866 1.00 129.63 ?  8   SER G CA  1 
ATOM   4290 C C   . SER C 3 1   ? 130.280 171.071 173.073 1.00 129.63 ?  8   SER G C   1 
ATOM   4291 O O   . SER C 3 1   ? 131.406 170.588 172.960 1.00 129.63 ?  8   SER G O   1 
ATOM   4292 C CB  . SER C 3 1   ? 127.954 171.607 172.312 1.00 129.63 ?  8   SER G CB  1 
ATOM   4293 O OG  . SER C 3 1   ? 127.580 170.957 173.514 1.00 129.63 ?  8   SER G OG  1 
ATOM   4294 N N   . ILE C 3 2   ? 129.796 171.531 174.229 1.00 129.18 ?  9   ILE G N   1 
ATOM   4295 C CA  . ILE C 3 2   ? 130.593 171.460 175.451 1.00 129.18 ?  9   ILE G CA  1 
ATOM   4296 C C   . ILE C 3 2   ? 130.828 170.009 175.849 1.00 129.18 ?  9   ILE G C   1 
ATOM   4297 O O   . ILE C 3 2   ? 131.924 169.640 176.290 1.00 129.18 ?  9   ILE G O   1 
ATOM   4298 C CB  . ILE C 3 2   ? 129.911 172.255 176.580 1.00 129.18 ?  9   ILE G CB  1 
ATOM   4299 C CG1 . ILE C 3 2   ? 129.662 173.698 176.138 1.00 129.18 ?  9   ILE G CG1 1 
ATOM   4300 C CG2 . ILE C 3 2   ? 130.758 172.224 177.843 1.00 129.18 ?  9   ILE G CG2 1 
ATOM   4301 C CD1 . ILE C 3 2   ? 130.910 174.422 175.688 1.00 129.18 ?  9   ILE G CD1 1 
ATOM   4302 N N   . ALA C 3 3   ? 129.803 169.165 175.708 1.00 128.61 ?  10  ALA G N   1 
ATOM   4303 C CA  . ALA C 3 3   ? 129.953 167.753 176.044 1.00 128.61 ?  10  ALA G CA  1 
ATOM   4304 C C   . ALA C 3 3   ? 130.984 167.077 175.149 1.00 128.61 ?  10  ALA G C   1 
ATOM   4305 O O   . ALA C 3 3   ? 131.783 166.258 175.618 1.00 128.61 ?  10  ALA G O   1 
ATOM   4306 C CB  . ALA C 3 3   ? 128.604 167.042 175.942 1.00 128.61 ?  10  ALA G CB  1 
ATOM   4307 N N   . GLN C 3 4   ? 130.978 167.404 173.854 1.00 127.88 ?  11  GLN G N   1 
ATOM   4308 C CA  . GLN C 3 4   ? 131.964 166.834 172.942 1.00 127.88 ?  11  GLN G CA  1 
ATOM   4309 C C   . GLN C 3 4   ? 133.377 167.252 173.327 1.00 127.88 ?  11  GLN G C   1 
ATOM   4310 O O   . GLN C 3 4   ? 134.302 166.431 173.313 1.00 127.88 ?  11  GLN G O   1 
ATOM   4311 C CB  . GLN C 3 4   ? 131.651 167.253 171.506 1.00 127.88 ?  11  GLN G CB  1 
ATOM   4312 C CG  . GLN C 3 4   ? 132.661 166.766 170.481 1.00 127.88 ?  11  GLN G CG  1 
ATOM   4313 C CD  . GLN C 3 4   ? 132.646 165.260 170.320 1.00 127.88 ?  11  GLN G CD  1 
ATOM   4314 O OE1 . GLN C 3 4   ? 133.542 164.564 170.797 1.00 127.88 ?  11  GLN G OE1 1 
ATOM   4315 N NE2 . GLN C 3 4   ? 131.624 164.748 169.645 1.00 127.88 ?  11  GLN G NE2 1 
ATOM   4316 N N   . ALA C 3 5   ? 133.563 168.528 173.676 1.00 126.50 ?  12  ALA G N   1 
ATOM   4317 C CA  . ALA C 3 5   ? 134.881 168.997 174.090 1.00 126.50 ?  12  ALA G CA  1 
ATOM   4318 C C   . ALA C 3 5   ? 135.330 168.318 175.378 1.00 126.50 ?  12  ALA G C   1 
ATOM   4319 O O   . ALA C 3 5   ? 136.503 167.951 175.518 1.00 126.50 ?  12  ALA G O   1 
ATOM   4320 C CB  . ALA C 3 5   ? 134.868 170.516 174.260 1.00 126.50 ?  12  ALA G CB  1 
ATOM   4321 N N   . ARG C 3 6   ? 134.413 168.151 176.334 1.00 125.17 ?  13  ARG G N   1 
ATOM   4322 C CA  . ARG C 3 6   ? 134.758 167.464 177.574 1.00 125.17 ?  13  ARG G CA  1 
ATOM   4323 C C   . ARG C 3 6   ? 135.149 166.016 177.311 1.00 125.17 ?  13  ARG G C   1 
ATOM   4324 O O   . ARG C 3 6   ? 136.122 165.513 177.884 1.00 125.17 ?  13  ARG G O   1 
ATOM   4325 C CB  . ARG C 3 6   ? 133.593 167.537 178.560 1.00 125.17 ?  13  ARG G CB  1 
ATOM   4326 C CG  . ARG C 3 6   ? 133.355 168.921 179.139 1.00 125.17 ?  13  ARG G CG  1 
ATOM   4327 C CD  . ARG C 3 6   ? 134.598 169.441 179.843 1.00 125.17 ?  13  ARG G CD  1 
ATOM   4328 N NE  . ARG C 3 6   ? 135.020 168.563 180.928 1.00 125.17 ?  13  ARG G NE  1 
ATOM   4329 C CZ  . ARG C 3 6   ? 134.507 168.582 182.151 1.00 125.17 ?  13  ARG G CZ  1 
ATOM   4330 N NH1 . ARG C 3 6   ? 133.543 169.425 182.483 1.00 125.17 1  13  ARG G NH1 1 
ATOM   4331 N NH2 . ARG C 3 6   ? 134.973 167.735 183.064 1.00 125.17 ?  13  ARG G NH2 1 
ATOM   4332 N N   . LYS C 3 7   ? 134.403 165.331 176.441 1.00 122.14 ?  14  LYS G N   1 
ATOM   4333 C CA  . LYS C 3 7   ? 134.753 163.959 176.090 1.00 122.14 ?  14  LYS G CA  1 
ATOM   4334 C C   . LYS C 3 7   ? 136.123 163.894 175.430 1.00 122.14 ?  14  LYS G C   1 
ATOM   4335 O O   . LYS C 3 7   ? 136.931 163.011 175.742 1.00 122.14 ?  14  LYS G O   1 
ATOM   4336 C CB  . LYS C 3 7   ? 133.686 163.366 175.170 1.00 122.14 ?  14  LYS G CB  1 
ATOM   4337 C CG  . LYS C 3 7   ? 132.391 162.998 175.873 1.00 122.14 ?  14  LYS G CG  1 
ATOM   4338 C CD  . LYS C 3 7   ? 132.516 161.668 176.595 1.00 122.14 ?  14  LYS G CD  1 
ATOM   4339 C CE  . LYS C 3 7   ? 132.625 160.516 175.610 1.00 122.14 ?  14  LYS G CE  1 
ATOM   4340 N NZ  . LYS C 3 7   ? 131.469 160.479 174.672 1.00 122.14 1  14  LYS G NZ  1 
ATOM   4341 N N   . LEU C 3 8   ? 136.407 164.829 174.520 1.00 118.41 ?  15  LEU G N   1 
ATOM   4342 C CA  . LEU C 3 8   ? 137.693 164.828 173.832 1.00 118.41 ?  15  LEU G CA  1 
ATOM   4343 C C   . LEU C 3 8   ? 138.844 165.071 174.801 1.00 118.41 ?  15  LEU G C   1 
ATOM   4344 O O   . LEU C 3 8   ? 139.871 164.384 174.738 1.00 118.41 ?  15  LEU G O   1 
ATOM   4345 C CB  . LEU C 3 8   ? 137.695 165.878 172.722 1.00 118.41 ?  15  LEU G CB  1 
ATOM   4346 C CG  . LEU C 3 8   ? 138.934 165.903 171.825 1.00 118.41 ?  15  LEU G CG  1 
ATOM   4347 C CD1 . LEU C 3 8   ? 139.151 164.548 171.173 1.00 118.41 ?  15  LEU G CD1 1 
ATOM   4348 C CD2 . LEU C 3 8   ? 138.811 166.994 170.773 1.00 118.41 ?  15  LEU G CD2 1 
ATOM   4349 N N   . VAL C 3 9   ? 138.696 166.042 175.705 1.00 117.97 ?  16  VAL G N   1 
ATOM   4350 C CA  . VAL C 3 9   ? 139.783 166.336 176.634 1.00 117.97 ?  16  VAL G CA  1 
ATOM   4351 C C   . VAL C 3 9   ? 139.962 165.196 177.630 1.00 117.97 ?  16  VAL G C   1 
ATOM   4352 O O   . VAL C 3 9   ? 141.089 164.878 178.024 1.00 117.97 ?  16  VAL G O   1 
ATOM   4353 C CB  . VAL C 3 9   ? 139.567 167.691 177.337 1.00 117.97 ?  16  VAL G CB  1 
ATOM   4354 C CG1 . VAL C 3 9   ? 139.477 168.809 176.311 1.00 117.97 ?  16  VAL G CG1 1 
ATOM   4355 C CG2 . VAL C 3 9   ? 138.337 167.672 178.225 1.00 117.97 ?  16  VAL G CG2 1 
ATOM   4356 N N   . GLU C 3 10  ? 138.867 164.552 178.046 1.00 116.42 ?  17  GLU G N   1 
ATOM   4357 C CA  . GLU C 3 10  ? 138.993 163.397 178.930 1.00 116.42 ?  17  GLU G CA  1 
ATOM   4358 C C   . GLU C 3 10  ? 139.705 162.244 178.233 1.00 116.42 ?  17  GLU G C   1 
ATOM   4359 O O   . GLU C 3 10  ? 140.567 161.585 178.830 1.00 116.42 ?  17  GLU G O   1 
ATOM   4360 C CB  . GLU C 3 10  ? 137.614 162.960 179.423 1.00 116.42 ?  17  GLU G CB  1 
ATOM   4361 C CG  . GLU C 3 10  ? 137.647 161.790 180.391 1.00 116.42 ?  17  GLU G CG  1 
ATOM   4362 C CD  . GLU C 3 10  ? 138.352 162.131 181.689 1.00 116.42 ?  17  GLU G CD  1 
ATOM   4363 O OE1 . GLU C 3 10  ? 138.208 163.278 182.162 1.00 116.42 ?  17  GLU G OE1 1 
ATOM   4364 O OE2 . GLU C 3 10  ? 139.051 161.252 182.235 1.00 116.42 -1 17  GLU G OE2 1 
ATOM   4365 N N   . GLN C 3 11  ? 139.363 161.990 176.967 1.00 108.04 ?  18  GLN G N   1 
ATOM   4366 C CA  . GLN C 3 11  ? 140.036 160.936 176.217 1.00 108.04 ?  18  GLN G CA  1 
ATOM   4367 C C   . GLN C 3 11  ? 141.517 161.244 176.045 1.00 108.04 ?  18  GLN G C   1 
ATOM   4368 O O   . GLN C 3 11  ? 142.363 160.354 176.181 1.00 108.04 ?  18  GLN G O   1 
ATOM   4369 C CB  . GLN C 3 11  ? 139.361 160.749 174.857 1.00 108.04 ?  18  GLN G CB  1 
ATOM   4370 C CG  . GLN C 3 11  ? 140.143 159.884 173.883 1.00 108.04 ?  18  GLN G CG  1 
ATOM   4371 C CD  . GLN C 3 11  ? 140.241 158.440 174.332 1.00 108.04 ?  18  GLN G CD  1 
ATOM   4372 O OE1 . GLN C 3 11  ? 139.399 157.953 175.087 1.00 108.04 ?  18  GLN G OE1 1 
ATOM   4373 N NE2 . GLN C 3 11  ? 141.272 157.745 173.868 1.00 108.04 ?  18  GLN G NE2 1 
ATOM   4374 N N   . LEU C 3 12  ? 141.851 162.503 175.754 1.00 110.59 ?  19  LEU G N   1 
ATOM   4375 C CA  . LEU C 3 12  ? 143.254 162.877 175.605 1.00 110.59 ?  19  LEU G CA  1 
ATOM   4376 C C   . LEU C 3 12  ? 144.006 162.747 176.925 1.00 110.59 ?  19  LEU G C   1 
ATOM   4377 O O   . LEU C 3 12  ? 145.162 162.308 176.944 1.00 110.59 ?  19  LEU G O   1 
ATOM   4378 C CB  . LEU C 3 12  ? 143.364 164.298 175.056 1.00 110.59 ?  19  LEU G CB  1 
ATOM   4379 C CG  . LEU C 3 12  ? 143.154 164.442 173.547 1.00 110.59 ?  19  LEU G CG  1 
ATOM   4380 C CD1 . LEU C 3 12  ? 143.168 165.905 173.139 1.00 110.59 ?  19  LEU G CD1 1 
ATOM   4381 C CD2 . LEU C 3 12  ? 144.205 163.659 172.780 1.00 110.59 ?  19  LEU G CD2 1 
ATOM   4382 N N   . LYS C 3 13  ? 143.371 163.129 178.037 1.00 111.12 ?  20  LYS G N   1 
ATOM   4383 C CA  . LYS C 3 13  ? 143.995 162.962 179.345 1.00 111.12 ?  20  LYS G CA  1 
ATOM   4384 C C   . LYS C 3 13  ? 144.257 161.493 179.645 1.00 111.12 ?  20  LYS G C   1 
ATOM   4385 O O   . LYS C 3 13  ? 145.325 161.136 180.155 1.00 111.12 ?  20  LYS G O   1 
ATOM   4386 C CB  . LYS C 3 13  ? 143.111 163.575 180.432 1.00 111.12 ?  20  LYS G CB  1 
ATOM   4387 C CG  . LYS C 3 13  ? 143.439 165.018 180.773 1.00 111.12 ?  20  LYS G CG  1 
ATOM   4388 C CD  . LYS C 3 13  ? 142.700 165.474 182.020 1.00 111.12 ?  20  LYS G CD  1 
ATOM   4389 C CE  . LYS C 3 13  ? 141.260 165.845 181.705 1.00 111.12 ?  20  LYS G CE  1 
ATOM   4390 N NZ  . LYS C 3 13  ? 141.172 166.905 180.663 1.00 111.12 1  20  LYS G NZ  1 
ATOM   4391 N N   . MET C 3 14  ? 143.290 160.627 179.339 1.00 109.27 ?  21  MET G N   1 
ATOM   4392 C CA  . MET C 3 14  ? 143.463 159.205 179.615 1.00 109.27 ?  21  MET G CA  1 
ATOM   4393 C C   . MET C 3 14  ? 144.516 158.589 178.700 1.00 109.27 ?  21  MET G C   1 
ATOM   4394 O O   . MET C 3 14  ? 145.240 157.671 179.103 1.00 109.27 ?  21  MET G O   1 
ATOM   4395 C CB  . MET C 3 14  ? 142.126 158.480 179.469 1.00 109.27 ?  21  MET G CB  1 
ATOM   4396 C CG  . MET C 3 14  ? 142.179 156.998 179.786 1.00 109.27 ?  21  MET G CG  1 
ATOM   4397 S SD  . MET C 3 14  ? 140.568 156.210 179.621 1.00 109.27 ?  21  MET G SD  1 
ATOM   4398 C CE  . MET C 3 14  ? 140.371 156.211 177.841 1.00 109.27 ?  21  MET G CE  1 
ATOM   4399 N N   . GLU C 3 15  ? 144.620 159.085 177.465 1.00 103.32 ?  22  GLU G N   1 
ATOM   4400 C CA  . GLU C 3 15  ? 145.584 158.528 176.522 1.00 103.32 ?  22  GLU G CA  1 
ATOM   4401 C C   . GLU C 3 15  ? 147.004 158.984 176.836 1.00 103.32 ?  22  GLU G C   1 
ATOM   4402 O O   . GLU C 3 15  ? 147.954 158.202 176.713 1.00 103.32 ?  22  GLU G O   1 
ATOM   4403 C CB  . GLU C 3 15  ? 145.199 158.919 175.096 1.00 103.32 ?  22  GLU G CB  1 
ATOM   4404 C CG  . GLU C 3 15  ? 146.178 158.451 174.034 1.00 103.32 ?  22  GLU G CG  1 
ATOM   4405 C CD  . GLU C 3 15  ? 145.594 158.521 172.638 1.00 103.32 ?  22  GLU G CD  1 
ATOM   4406 O OE1 . GLU C 3 15  ? 144.353 158.583 172.515 1.00 103.32 ?  22  GLU G OE1 1 
ATOM   4407 O OE2 . GLU C 3 15  ? 146.377 158.515 171.665 1.00 103.32 -1 22  GLU G OE2 1 
ATOM   4408 N N   . ALA C 3 16  ? 147.172 160.242 177.245 1.00 106.83 ?  23  ALA G N   1 
ATOM   4409 C CA  . ALA C 3 16  ? 148.499 160.801 177.468 1.00 106.83 ?  23  ALA G CA  1 
ATOM   4410 C C   . ALA C 3 16  ? 149.159 160.299 178.745 1.00 106.83 ?  23  ALA G C   1 
ATOM   4411 O O   . ALA C 3 16  ? 150.350 160.560 178.947 1.00 106.83 ?  23  ALA G O   1 
ATOM   4412 C CB  . ALA C 3 16  ? 148.425 162.329 177.501 1.00 106.83 ?  23  ALA G CB  1 
ATOM   4413 N N   . ASN C 3 17  ? 148.429 159.590 179.606 1.00 107.59 ?  24  ASN G N   1 
ATOM   4414 C CA  . ASN C 3 17  ? 148.960 159.107 180.875 1.00 107.59 ?  24  ASN G CA  1 
ATOM   4415 C C   . ASN C 3 17  ? 149.348 157.634 180.821 1.00 107.59 ?  24  ASN G C   1 
ATOM   4416 O O   . ASN C 3 17  ? 149.207 156.918 181.818 1.00 107.59 ?  24  ASN G O   1 
ATOM   4417 C CB  . ASN C 3 17  ? 147.950 159.350 181.996 1.00 107.59 ?  24  ASN G CB  1 
ATOM   4418 C CG  . ASN C 3 17  ? 147.821 160.816 182.357 1.00 107.59 ?  24  ASN G CG  1 
ATOM   4419 O OD1 . ASN C 3 17  ? 148.747 161.601 182.150 1.00 107.59 ?  24  ASN G OD1 1 
ATOM   4420 N ND2 . ASN C 3 17  ? 146.670 161.193 182.901 1.00 107.59 ?  24  ASN G ND2 1 
ATOM   4421 N N   . ILE C 3 18  ? 149.836 157.165 179.677 1.00 102.16 ?  25  ILE G N   1 
ATOM   4422 C CA  . ILE C 3 18  ? 150.255 155.781 179.519 1.00 102.16 ?  25  ILE G CA  1 
ATOM   4423 C C   . ILE C 3 18  ? 151.776 155.723 179.518 1.00 102.16 ?  25  ILE G C   1 
ATOM   4424 O O   . ILE C 3 18  ? 152.467 156.711 179.253 1.00 102.16 ?  25  ILE G O   1 
ATOM   4425 C CB  . ILE C 3 18  ? 149.680 155.141 178.239 1.00 102.16 ?  25  ILE G CB  1 
ATOM   4426 C CG1 . ILE C 3 18  ? 150.224 155.848 176.997 1.00 102.16 ?  25  ILE G CG1 1 
ATOM   4427 C CG2 . ILE C 3 18  ? 148.161 155.184 178.259 1.00 102.16 ?  25  ILE G CG2 1 
ATOM   4428 C CD1 . ILE C 3 18  ? 150.239 154.979 175.761 1.00 102.16 ?  25  ILE G CD1 1 
ATOM   4429 N N   . ASP C 3 19  ? 152.300 154.539 179.823 1.00 104.30 ?  26  ASP G N   1 
ATOM   4430 C CA  . ASP C 3 19  ? 153.738 154.319 179.873 1.00 104.30 ?  26  ASP G CA  1 
ATOM   4431 C C   . ASP C 3 19  ? 154.247 153.919 178.494 1.00 104.30 ?  26  ASP G C   1 
ATOM   4432 O O   . ASP C 3 19  ? 153.735 152.973 177.887 1.00 104.30 ?  26  ASP G O   1 
ATOM   4433 C CB  . ASP C 3 19  ? 154.085 153.240 180.899 1.00 104.30 ?  26  ASP G CB  1 
ATOM   4434 C CG  . ASP C 3 19  ? 153.760 153.661 182.319 1.00 104.30 ?  26  ASP G CG  1 
ATOM   4435 O OD1 . ASP C 3 19  ? 153.366 154.829 182.518 1.00 104.30 ?  26  ASP G OD1 1 
ATOM   4436 O OD2 . ASP C 3 19  ? 153.900 152.824 183.235 1.00 104.30 -1 26  ASP G OD2 1 
ATOM   4437 N N   . ARG C 3 20  ? 155.251 154.640 178.007 1.00 95.96  ?  27  ARG G N   1 
ATOM   4438 C CA  . ARG C 3 20  ? 155.841 154.395 176.699 1.00 95.96  ?  27  ARG G CA  1 
ATOM   4439 C C   . ARG C 3 20  ? 157.282 153.938 176.871 1.00 95.96  ?  27  ARG G C   1 
ATOM   4440 O O   . ARG C 3 20  ? 158.063 154.588 177.573 1.00 95.96  ?  27  ARG G O   1 
ATOM   4441 C CB  . ARG C 3 20  ? 155.788 155.652 175.829 1.00 95.96  ?  27  ARG G CB  1 
ATOM   4442 C CG  . ARG C 3 20  ? 154.424 155.941 175.230 1.00 95.96  ?  27  ARG G CG  1 
ATOM   4443 C CD  . ARG C 3 20  ? 154.418 157.274 174.503 1.00 95.96  ?  27  ARG G CD  1 
ATOM   4444 N NE  . ARG C 3 20  ? 153.067 157.788 174.316 1.00 95.96  ?  27  ARG G NE  1 
ATOM   4445 C CZ  . ARG C 3 20  ? 152.395 158.478 175.227 1.00 95.96  ?  27  ARG G CZ  1 
ATOM   4446 N NH1 . ARG C 3 20  ? 152.922 158.757 176.408 1.00 95.96  1  27  ARG G NH1 1 
ATOM   4447 N NH2 . ARG C 3 20  ? 151.165 158.897 174.947 1.00 95.96  ?  27  ARG G NH2 1 
ATOM   4448 N N   . ILE C 3 21  ? 157.628 152.827 176.232 1.00 92.04  ?  28  ILE G N   1 
ATOM   4449 C CA  . ILE C 3 21  ? 158.995 152.335 176.245 1.00 92.04  ?  28  ILE G CA  1 
ATOM   4450 C C   . ILE C 3 21  ? 159.751 152.952 175.077 1.00 92.04  ?  28  ILE G C   1 
ATOM   4451 O O   . ILE C 3 21  ? 159.162 153.496 174.139 1.00 92.04  ?  28  ILE G O   1 
ATOM   4452 C CB  . ILE C 3 21  ? 159.054 150.796 176.192 1.00 92.04  ?  28  ILE G CB  1 
ATOM   4453 C CG1 . ILE C 3 21  ? 158.521 150.286 174.853 1.00 92.04  ?  28  ILE G CG1 1 
ATOM   4454 C CG2 . ILE C 3 21  ? 158.267 150.194 177.344 1.00 92.04  ?  28  ILE G CG2 1 
ATOM   4455 C CD1 . ILE C 3 21  ? 158.541 148.780 174.726 1.00 92.04  ?  28  ILE G CD1 1 
ATOM   4456 N N   . LYS C 3 22  ? 161.077 152.874 175.139 1.00 93.26  ?  29  LYS G N   1 
ATOM   4457 C CA  . LYS C 3 22  ? 161.907 153.416 174.075 1.00 93.26  ?  29  LYS G CA  1 
ATOM   4458 C C   . LYS C 3 22  ? 161.670 152.660 172.773 1.00 93.26  ?  29  LYS G C   1 
ATOM   4459 O O   . LYS C 3 22  ? 161.401 151.456 172.765 1.00 93.26  ?  29  LYS G O   1 
ATOM   4460 C CB  . LYS C 3 22  ? 163.384 153.348 174.461 1.00 93.26  ?  29  LYS G CB  1 
ATOM   4461 C CG  . LYS C 3 22  ? 163.737 154.158 175.695 1.00 93.26  ?  29  LYS G CG  1 
ATOM   4462 C CD  . LYS C 3 22  ? 163.585 155.647 175.436 1.00 93.26  ?  29  LYS G CD  1 
ATOM   4463 C CE  . LYS C 3 22  ? 164.012 156.466 176.642 1.00 93.26  ?  29  LYS G CE  1 
ATOM   4464 N NZ  . LYS C 3 22  ? 163.827 157.925 176.413 1.00 93.26  1  29  LYS G NZ  1 
ATOM   4465 N N   . VAL C 3 23  ? 161.768 153.389 171.659 1.00 90.52  ?  30  VAL G N   1 
ATOM   4466 C CA  . VAL C 3 23  ? 161.534 152.787 170.350 1.00 90.52  ?  30  VAL G CA  1 
ATOM   4467 C C   . VAL C 3 23  ? 162.584 151.728 170.049 1.00 90.52  ?  30  VAL G C   1 
ATOM   4468 O O   . VAL C 3 23  ? 162.284 150.705 169.423 1.00 90.52  ?  30  VAL G O   1 
ATOM   4469 C CB  . VAL C 3 23  ? 161.494 153.880 169.263 1.00 90.52  ?  30  VAL G CB  1 
ATOM   4470 C CG1 . VAL C 3 23  ? 161.591 153.269 167.873 1.00 90.52  ?  30  VAL G CG1 1 
ATOM   4471 C CG2 . VAL C 3 23  ? 160.225 154.702 169.393 1.00 90.52  ?  30  VAL G CG2 1 
ATOM   4472 N N   . SER C 3 24  ? 163.825 151.945 170.493 1.00 91.37  ?  31  SER G N   1 
ATOM   4473 C CA  . SER C 3 24  ? 164.882 150.970 170.243 1.00 91.37  ?  31  SER G CA  1 
ATOM   4474 C C   . SER C 3 24  ? 164.574 149.629 170.901 1.00 91.37  ?  31  SER G C   1 
ATOM   4475 O O   . SER C 3 24  ? 164.779 148.573 170.293 1.00 91.37  ?  31  SER G O   1 
ATOM   4476 C CB  . SER C 3 24  ? 166.222 151.512 170.738 1.00 91.37  ?  31  SER G CB  1 
ATOM   4477 O OG  . SER C 3 24  ? 166.160 151.842 172.114 1.00 91.37  ?  31  SER G OG  1 
ATOM   4478 N N   . LYS C 3 25  ? 164.082 149.651 172.142 1.00 91.14  ?  32  LYS G N   1 
ATOM   4479 C CA  . LYS C 3 25  ? 163.799 148.402 172.846 1.00 91.14  ?  32  LYS G CA  1 
ATOM   4480 C C   . LYS C 3 25  ? 162.688 147.613 172.163 1.00 91.14  ?  32  LYS G C   1 
ATOM   4481 O O   . LYS C 3 25  ? 162.802 146.395 171.984 1.00 91.14  ?  32  LYS G O   1 
ATOM   4482 C CB  . LYS C 3 25  ? 163.432 148.692 174.301 1.00 91.14  ?  32  LYS G CB  1 
ATOM   4483 C CG  . LYS C 3 25  ? 162.895 147.486 175.052 1.00 91.14  ?  32  LYS G CG  1 
ATOM   4484 C CD  . LYS C 3 25  ? 162.515 147.844 176.477 1.00 91.14  ?  32  LYS G CD  1 
ATOM   4485 C CE  . LYS C 3 25  ? 161.805 146.689 177.164 1.00 91.14  ?  32  LYS G CE  1 
ATOM   4486 N NZ  . LYS C 3 25  ? 162.659 145.470 177.222 1.00 91.14  1  32  LYS G NZ  1 
ATOM   4487 N N   . ALA C 3 26  ? 161.610 148.288 171.765 1.00 86.86  ?  33  ALA G N   1 
ATOM   4488 C CA  . ALA C 3 26  ? 160.516 147.589 171.101 1.00 86.86  ?  33  ALA G CA  1 
ATOM   4489 C C   . ALA C 3 26  ? 160.907 147.132 169.702 1.00 86.86  ?  33  ALA G C   1 
ATOM   4490 O O   . ALA C 3 26  ? 160.455 146.075 169.245 1.00 86.86  ?  33  ALA G O   1 
ATOM   4491 C CB  . ALA C 3 26  ? 159.282 148.484 171.051 1.00 86.86  ?  33  ALA G CB  1 
ATOM   4492 N N   . ALA C 3 27  ? 161.741 147.909 169.009 1.00 85.31  ?  34  ALA G N   1 
ATOM   4493 C CA  . ALA C 3 27  ? 162.276 147.465 167.728 1.00 85.31  ?  34  ALA G CA  1 
ATOM   4494 C C   . ALA C 3 27  ? 163.113 146.204 167.896 1.00 85.31  ?  34  ALA G C   1 
ATOM   4495 O O   . ALA C 3 27  ? 163.018 145.272 167.089 1.00 85.31  ?  34  ALA G O   1 
ATOM   4496 C CB  . ALA C 3 27  ? 163.104 148.581 167.094 1.00 85.31  ?  34  ALA G CB  1 
ATOM   4497 N N   . ALA C 3 28  ? 163.935 146.158 168.946 1.00 85.25  ?  35  ALA G N   1 
ATOM   4498 C CA  . ALA C 3 28  ? 164.708 144.956 169.232 1.00 85.25  ?  35  ALA G CA  1 
ATOM   4499 C C   . ALA C 3 28  ? 163.796 143.784 169.567 1.00 85.25  ?  35  ALA G C   1 
ATOM   4500 O O   . ALA C 3 28  ? 164.082 142.642 169.197 1.00 85.25  ?  35  ALA G O   1 
ATOM   4501 C CB  . ALA C 3 28  ? 165.688 145.220 170.375 1.00 85.25  ?  35  ALA G CB  1 
ATOM   4502 N N   . ASP C 3 29  ? 162.697 144.047 170.278 1.00 86.30  ?  36  ASP G N   1 
ATOM   4503 C CA  . ASP C 3 29  ? 161.745 142.984 170.586 1.00 86.30  ?  36  ASP G CA  1 
ATOM   4504 C C   . ASP C 3 29  ? 161.113 142.420 169.318 1.00 86.30  ?  36  ASP G C   1 
ATOM   4505 O O   . ASP C 3 29  ? 160.993 141.198 169.164 1.00 86.30  ?  36  ASP G O   1 
ATOM   4506 C CB  . ASP C 3 29  ? 160.666 143.505 171.534 1.00 86.30  ?  36  ASP G CB  1 
ATOM   4507 C CG  . ASP C 3 29  ? 161.127 143.544 172.977 1.00 86.30  ?  36  ASP G CG  1 
ATOM   4508 O OD1 . ASP C 3 29  ? 162.354 143.557 173.209 1.00 86.30  ?  36  ASP G OD1 1 
ATOM   4509 O OD2 . ASP C 3 29  ? 160.264 143.563 173.878 1.00 86.30  -1 36  ASP G OD2 1 
ATOM   4510 N N   . LEU C 3 30  ? 160.704 143.297 168.398 1.00 79.69  ?  37  LEU G N   1 
ATOM   4511 C CA  . LEU C 3 30  ? 160.145 142.834 167.130 1.00 79.69  ?  37  LEU G CA  1 
ATOM   4512 C C   . LEU C 3 30  ? 161.177 142.056 166.322 1.00 79.69  ?  37  LEU G C   1 
ATOM   4513 O O   . LEU C 3 30  ? 160.858 141.026 165.714 1.00 79.69  ?  37  LEU G O   1 
ATOM   4514 C CB  . LEU C 3 30  ? 159.618 144.017 166.319 1.00 79.69  ?  37  LEU G CB  1 
ATOM   4515 C CG  . LEU C 3 30  ? 158.121 144.319 166.419 1.00 79.69  ?  37  LEU G CG  1 
ATOM   4516 C CD1 . LEU C 3 30  ? 157.770 144.912 167.773 1.00 79.69  ?  37  LEU G CD1 1 
ATOM   4517 C CD2 . LEU C 3 30  ? 157.693 145.246 165.295 1.00 79.69  ?  37  LEU G CD2 1 
ATOM   4518 N N   . MET C 3 31  ? 162.421 142.539 166.303 1.00 84.02  ?  38  MET G N   1 
ATOM   4519 C CA  . MET C 3 31  ? 163.484 141.838 165.590 1.00 84.02  ?  38  MET G CA  1 
ATOM   4520 C C   . MET C 3 31  ? 163.727 140.456 166.184 1.00 84.02  ?  38  MET G C   1 
ATOM   4521 O O   . MET C 3 31  ? 163.904 139.477 165.449 1.00 84.02  ?  38  MET G O   1 
ATOM   4522 C CB  . MET C 3 31  ? 164.760 142.676 165.624 1.00 84.02  ?  38  MET G CB  1 
ATOM   4523 C CG  . MET C 3 31  ? 165.933 142.085 164.872 1.00 84.02  ?  38  MET G CG  1 
ATOM   4524 S SD  . MET C 3 31  ? 167.372 143.167 164.957 1.00 84.02  ?  38  MET G SD  1 
ATOM   4525 C CE  . MET C 3 31  ? 167.855 142.951 166.668 1.00 84.02  ?  38  MET G CE  1 
ATOM   4526 N N   . ALA C 3 32  ? 163.735 140.357 167.514 1.00 80.71  ?  39  ALA G N   1 
ATOM   4527 C CA  . ALA C 3 32  ? 163.924 139.068 168.169 1.00 80.71  ?  39  ALA G CA  1 
ATOM   4528 C C   . ALA C 3 32  ? 162.767 138.124 167.878 1.00 80.71  ?  39  ALA G C   1 
ATOM   4529 O O   . ALA C 3 32  ? 162.977 136.922 167.680 1.00 80.71  ?  39  ALA G O   1 
ATOM   4530 C CB  . ALA C 3 32  ? 164.093 139.264 169.675 1.00 80.71  ?  39  ALA G CB  1 
ATOM   4531 N N   . TYR C 3 33  ? 161.536 138.643 167.862 1.00 75.28  ?  40  TYR G N   1 
ATOM   4532 C CA  . TYR C 3 33  ? 160.396 137.797 167.526 1.00 75.28  ?  40  TYR G CA  1 
ATOM   4533 C C   . TYR C 3 33  ? 160.493 137.287 166.094 1.00 75.28  ?  40  TYR G C   1 
ATOM   4534 O O   . TYR C 3 33  ? 160.197 136.118 165.823 1.00 75.28  ?  40  TYR G O   1 
ATOM   4535 C CB  . TYR C 3 33  ? 159.085 138.554 167.735 1.00 75.28  ?  40  TYR G CB  1 
ATOM   4536 C CG  . TYR C 3 33  ? 157.858 137.702 167.494 1.00 75.28  ?  40  TYR G CG  1 
ATOM   4537 C CD1 . TYR C 3 33  ? 157.307 136.943 168.517 1.00 75.28  ?  40  TYR G CD1 1 
ATOM   4538 C CD2 . TYR C 3 33  ? 157.253 137.653 166.245 1.00 75.28  ?  40  TYR G CD2 1 
ATOM   4539 C CE1 . TYR C 3 33  ? 156.190 136.161 168.303 1.00 75.28  ?  40  TYR G CE1 1 
ATOM   4540 C CE2 . TYR C 3 33  ? 156.137 136.873 166.023 1.00 75.28  ?  40  TYR G CE2 1 
ATOM   4541 C CZ  . TYR C 3 33  ? 155.609 136.130 167.055 1.00 75.28  ?  40  TYR G CZ  1 
ATOM   4542 O OH  . TYR C 3 33  ? 154.496 135.352 166.838 1.00 75.28  ?  40  TYR G OH  1 
ATOM   4543 N N   . CYS C 3 34  ? 160.899 138.151 165.161 1.00 79.05  ?  41  CYS G N   1 
ATOM   4544 C CA  . CYS C 3 34  ? 161.056 137.713 163.778 1.00 79.05  ?  41  CYS G CA  1 
ATOM   4545 C C   . CYS C 3 34  ? 162.182 136.697 163.633 1.00 79.05  ?  41  CYS G C   1 
ATOM   4546 O O   . CYS C 3 34  ? 162.085 135.780 162.810 1.00 79.05  ?  41  CYS G O   1 
ATOM   4547 C CB  . CYS C 3 34  ? 161.312 138.912 162.866 1.00 79.05  ?  41  CYS G CB  1 
ATOM   4548 S SG  . CYS C 3 34  ? 159.930 140.062 162.731 1.00 79.05  ?  41  CYS G SG  1 
ATOM   4549 N N   . GLU C 3 35  ? 163.253 136.844 164.415 1.00 84.89  ?  42  GLU G N   1 
ATOM   4550 C CA  . GLU C 3 35  ? 164.377 135.918 164.311 1.00 84.89  ?  42  GLU G CA  1 
ATOM   4551 C C   . GLU C 3 35  ? 164.043 134.564 164.925 1.00 84.89  ?  42  GLU G C   1 
ATOM   4552 O O   . GLU C 3 35  ? 164.427 133.520 164.385 1.00 84.89  ?  42  GLU G O   1 
ATOM   4553 C CB  . GLU C 3 35  ? 165.610 136.524 164.979 1.00 84.89  ?  42  GLU G CB  1 
ATOM   4554 C CG  . GLU C 3 35  ? 166.766 135.557 165.160 1.00 84.89  ?  42  GLU G CG  1 
ATOM   4555 C CD  . GLU C 3 35  ? 168.111 136.255 165.156 1.00 84.89  ?  42  GLU G CD  1 
ATOM   4556 O OE1 . GLU C 3 35  ? 168.133 137.504 165.159 1.00 84.89  ?  42  GLU G OE1 1 
ATOM   4557 O OE2 . GLU C 3 35  ? 169.146 135.556 165.150 1.00 84.89  -1 42  GLU G OE2 1 
ATOM   4558 N N   . ALA C 3 36  ? 163.329 134.560 166.053 1.00 80.88  ?  43  ALA G N   1 
ATOM   4559 C CA  . ALA C 3 36  ? 163.027 133.307 166.740 1.00 80.88  ?  43  ALA G CA  1 
ATOM   4560 C C   . ALA C 3 36  ? 162.120 132.414 165.903 1.00 80.88  ?  43  ALA G C   1 
ATOM   4561 O O   . ALA C 3 36  ? 162.297 131.191 165.874 1.00 80.88  ?  43  ALA G O   1 
ATOM   4562 C CB  . ALA C 3 36  ? 162.390 133.595 168.098 1.00 80.88  ?  43  ALA G CB  1 
ATOM   4563 N N   . HIS C 3 37  ? 161.143 133.004 165.215 1.00 81.24  ?  44  HIS G N   1 
ATOM   4564 C CA  . HIS C 3 37  ? 160.174 132.253 164.430 1.00 81.24  ?  44  HIS G CA  1 
ATOM   4565 C C   . HIS C 3 37  ? 160.527 132.212 162.948 1.00 81.24  ?  44  HIS G C   1 
ATOM   4566 O O   . HIS C 3 37  ? 159.668 131.887 162.122 1.00 81.24  ?  44  HIS G O   1 
ATOM   4567 C CB  . HIS C 3 37  ? 158.775 132.839 164.623 1.00 81.24  ?  44  HIS G CB  1 
ATOM   4568 C CG  . HIS C 3 37  ? 158.232 132.663 166.007 1.00 81.24  ?  44  HIS G CG  1 
ATOM   4569 N ND1 . HIS C 3 37  ? 158.834 133.211 167.118 1.00 81.24  ?  44  HIS G ND1 1 
ATOM   4570 C CD2 . HIS C 3 37  ? 157.142 131.999 166.459 1.00 81.24  ?  44  HIS G CD2 1 
ATOM   4571 C CE1 . HIS C 3 37  ? 158.139 132.892 168.195 1.00 81.24  ?  44  HIS G CE1 1 
ATOM   4572 N NE2 . HIS C 3 37  ? 157.107 132.157 167.823 1.00 81.24  ?  44  HIS G NE2 1 
ATOM   4573 N N   . ALA C 3 38  ? 161.773 132.537 162.596 1.00 83.79  ?  45  ALA G N   1 
ATOM   4574 C CA  . ALA C 3 38  ? 162.172 132.533 161.192 1.00 83.79  ?  45  ALA G CA  1 
ATOM   4575 C C   . ALA C 3 38  ? 162.088 131.135 160.593 1.00 83.79  ?  45  ALA G C   1 
ATOM   4576 O O   . ALA C 3 38  ? 161.654 130.968 159.447 1.00 83.79  ?  45  ALA G O   1 
ATOM   4577 C CB  . ALA C 3 38  ? 163.586 133.094 161.048 1.00 83.79  ?  45  ALA G CB  1 
ATOM   4578 N N   . LYS C 3 39  ? 162.499 130.117 161.350 1.00 88.90  ?  46  LYS G N   1 
ATOM   4579 C CA  . LYS C 3 39  ? 162.493 128.748 160.848 1.00 88.90  ?  46  LYS G CA  1 
ATOM   4580 C C   . LYS C 3 39  ? 161.092 128.162 160.731 1.00 88.90  ?  46  LYS G C   1 
ATOM   4581 O O   . LYS C 3 39  ? 160.937 127.102 160.115 1.00 88.90  ?  46  LYS G O   1 
ATOM   4582 C CB  . LYS C 3 39  ? 163.346 127.856 161.753 1.00 88.90  ?  46  LYS G CB  1 
ATOM   4583 C CG  . LYS C 3 39  ? 164.822 128.248 161.868 1.00 88.90  ?  46  LYS G CG  1 
ATOM   4584 C CD  . LYS C 3 39  ? 165.618 127.983 160.589 1.00 88.90  ?  46  LYS G CD  1 
ATOM   4585 C CE  . LYS C 3 39  ? 165.697 129.202 159.678 1.00 88.90  ?  46  LYS G CE  1 
ATOM   4586 N NZ  . LYS C 3 39  ? 166.565 128.953 158.494 1.00 88.90  1  46  LYS G NZ  1 
ATOM   4587 N N   . GLU C 3 40  ? 160.078 128.815 161.297 1.00 85.44  ?  47  GLU G N   1 
ATOM   4588 C CA  . GLU C 3 40  ? 158.711 128.314 161.273 1.00 85.44  ?  47  GLU G CA  1 
ATOM   4589 C C   . GLU C 3 40  ? 157.824 129.076 160.294 1.00 85.44  ?  47  GLU G C   1 
ATOM   4590 O O   . GLU C 3 40  ? 156.596 128.991 160.387 1.00 85.44  ?  47  GLU G O   1 
ATOM   4591 C CB  . GLU C 3 40  ? 158.107 128.362 162.676 1.00 85.44  ?  47  GLU G CB  1 
ATOM   4592 C CG  . GLU C 3 40  ? 159.020 127.820 163.762 1.00 85.44  ?  47  GLU G CG  1 
ATOM   4593 C CD  . GLU C 3 40  ? 158.503 128.113 165.156 1.00 85.44  ?  47  GLU G CD  1 
ATOM   4594 O OE1 . GLU C 3 40  ? 157.386 128.659 165.274 1.00 85.44  ?  47  GLU G OE1 1 
ATOM   4595 O OE2 . GLU C 3 40  ? 159.213 127.800 166.134 1.00 85.44  -1 47  GLU G OE2 1 
ATOM   4596 N N   . ASP C 3 41  ? 158.418 129.817 159.360 1.00 76.57  ?  48  ASP G N   1 
ATOM   4597 C CA  . ASP C 3 41  ? 157.654 130.601 158.394 1.00 76.57  ?  48  ASP G CA  1 
ATOM   4598 C C   . ASP C 3 41  ? 157.801 129.977 157.013 1.00 76.57  ?  48  ASP G C   1 
ATOM   4599 O O   . ASP C 3 41  ? 158.838 130.159 156.357 1.00 76.57  ?  48  ASP G O   1 
ATOM   4600 C CB  . ASP C 3 41  ? 158.134 132.055 158.384 1.00 76.57  ?  48  ASP G CB  1 
ATOM   4601 C CG  . ASP C 3 41  ? 157.161 132.992 157.687 1.00 76.57  ?  48  ASP G CG  1 
ATOM   4602 O OD1 . ASP C 3 41  ? 156.349 132.521 156.864 1.00 76.57  ?  48  ASP G OD1 1 
ATOM   4603 O OD2 . ASP C 3 41  ? 157.212 134.209 157.963 1.00 76.57  -1 48  ASP G OD2 1 
ATOM   4604 N N   . PRO C 3 42  ? 156.807 129.227 156.532 1.00 75.14  ?  49  PRO G N   1 
ATOM   4605 C CA  . PRO C 3 42  ? 156.916 128.640 155.186 1.00 75.14  ?  49  PRO G CA  1 
ATOM   4606 C C   . PRO C 3 42  ? 157.050 129.669 154.078 1.00 75.14  ?  49  PRO G C   1 
ATOM   4607 O O   . PRO C 3 42  ? 157.706 129.393 153.066 1.00 75.14  ?  49  PRO G O   1 
ATOM   4608 C CB  . PRO C 3 42  ? 155.617 127.833 155.051 1.00 75.14  ?  49  PRO G CB  1 
ATOM   4609 C CG  . PRO C 3 42  ? 155.183 127.572 156.455 1.00 75.14  ?  49  PRO G CG  1 
ATOM   4610 C CD  . PRO C 3 42  ? 155.592 128.783 157.233 1.00 75.14  ?  49  PRO G CD  1 
ATOM   4611 N N   . LEU C 3 43  ? 156.436 130.843 154.226 1.00 73.05  ?  50  LEU G N   1 
ATOM   4612 C CA  . LEU C 3 43  ? 156.539 131.861 153.185 1.00 73.05  ?  50  LEU G CA  1 
ATOM   4613 C C   . LEU C 3 43  ? 157.935 132.467 153.138 1.00 73.05  ?  50  LEU G C   1 
ATOM   4614 O O   . LEU C 3 43  ? 158.443 132.788 152.058 1.00 73.05  ?  50  LEU G O   1 
ATOM   4615 C CB  . LEU C 3 43  ? 155.490 132.947 153.408 1.00 73.05  ?  50  LEU G CB  1 
ATOM   4616 C CG  . LEU C 3 43  ? 154.040 132.469 153.413 1.00 73.05  ?  50  LEU G CG  1 
ATOM   4617 C CD1 . LEU C 3 43  ? 153.165 133.446 154.174 1.00 73.05  ?  50  LEU G CD1 1 
ATOM   4618 C CD2 . LEU C 3 43  ? 153.537 132.280 151.994 1.00 73.05  ?  50  LEU G CD2 1 
ATOM   4619 N N   . LEU C 3 44  ? 158.569 132.637 154.299 1.00 77.65  ?  51  LEU G N   1 
ATOM   4620 C CA  . LEU C 3 44  ? 159.906 133.218 154.337 1.00 77.65  ?  51  LEU G CA  1 
ATOM   4621 C C   . LEU C 3 44  ? 160.941 132.241 153.795 1.00 77.65  ?  51  LEU G C   1 
ATOM   4622 O O   . LEU C 3 44  ? 161.609 132.514 152.791 1.00 77.65  ?  51  LEU G O   1 
ATOM   4623 C CB  . LEU C 3 44  ? 160.249 133.637 155.767 1.00 77.65  ?  51  LEU G CB  1 
ATOM   4624 C CG  . LEU C 3 44  ? 161.521 134.463 155.938 1.00 77.65  ?  51  LEU G CG  1 
ATOM   4625 C CD1 . LEU C 3 44  ? 161.322 135.848 155.357 1.00 77.65  ?  51  LEU G CD1 1 
ATOM   4626 C CD2 . LEU C 3 44  ? 161.908 134.543 157.404 1.00 77.65  ?  51  LEU G CD2 1 
ATOM   4627 N N   . THR C 3 45  ? 161.087 131.089 154.450 1.00 85.39  ?  52  THR G N   1 
ATOM   4628 C CA  . THR C 3 45  ? 161.984 130.045 153.982 1.00 85.39  ?  52  THR G CA  1 
ATOM   4629 C C   . THR C 3 45  ? 161.194 129.054 153.145 1.00 85.39  ?  52  THR G C   1 
ATOM   4630 O O   . THR C 3 45  ? 160.237 128.456 153.662 1.00 85.39  ?  52  THR G O   1 
ATOM   4631 C CB  . THR C 3 45  ? 162.645 129.333 155.156 1.00 85.39  ?  52  THR G CB  1 
ATOM   4632 O OG1 . THR C 3 45  ? 161.645 128.669 155.939 1.00 85.39  ?  52  THR G OG1 1 
ATOM   4633 C CG2 . THR C 3 45  ? 163.387 130.330 156.032 1.00 85.39  ?  52  THR G CG2 1 
ATOM   4634 N N   . PRO C 3 46  ? 161.538 128.852 151.873 1.00 91.61  ?  53  PRO G N   1 
ATOM   4635 C CA  . PRO C 3 46  ? 160.736 127.963 151.024 1.00 91.61  ?  53  PRO G CA  1 
ATOM   4636 C C   . PRO C 3 46  ? 160.659 126.556 151.597 1.00 91.61  ?  53  PRO G C   1 
ATOM   4637 O O   . PRO C 3 46  ? 161.634 126.026 152.136 1.00 91.61  ?  53  PRO G O   1 
ATOM   4638 C CB  . PRO C 3 46  ? 161.480 127.986 149.683 1.00 91.61  ?  53  PRO G CB  1 
ATOM   4639 C CG  . PRO C 3 46  ? 162.269 129.255 149.705 1.00 91.61  ?  53  PRO G CG  1 
ATOM   4640 C CD  . PRO C 3 46  ? 162.655 129.467 151.137 1.00 91.61  ?  53  PRO G CD  1 
ATOM   4641 N N   . VAL C 3 47  ? 159.481 125.954 151.476 1.00 92.85  ?  54  VAL G N   1 
ATOM   4642 C CA  . VAL C 3 47  ? 159.206 124.641 152.053 1.00 92.85  ?  54  VAL G CA  1 
ATOM   4643 C C   . VAL C 3 47  ? 159.442 123.578 150.985 1.00 92.85  ?  54  VAL G C   1 
ATOM   4644 O O   . VAL C 3 47  ? 159.178 123.825 149.799 1.00 92.85  ?  54  VAL G O   1 
ATOM   4645 C CB  . VAL C 3 47  ? 157.778 124.584 152.626 1.00 92.85  ?  54  VAL G CB  1 
ATOM   4646 C CG1 . VAL C 3 47  ? 156.737 124.516 151.513 1.00 92.85  ?  54  VAL G CG1 1 
ATOM   4647 C CG2 . VAL C 3 47  ? 157.619 123.422 153.594 1.00 92.85  ?  54  VAL G CG2 1 
ATOM   4648 N N   . PRO C 3 48  ? 159.981 122.412 151.341 1.00 94.50  ?  55  PRO G N   1 
ATOM   4649 C CA  . PRO C 3 48  ? 160.104 121.332 150.355 1.00 94.50  ?  55  PRO G CA  1 
ATOM   4650 C C   . PRO C 3 48  ? 158.742 120.906 149.828 1.00 94.50  ?  55  PRO G C   1 
ATOM   4651 O O   . PRO C 3 48  ? 157.748 120.895 150.557 1.00 94.50  ?  55  PRO G O   1 
ATOM   4652 C CB  . PRO C 3 48  ? 160.781 120.206 151.145 1.00 94.50  ?  55  PRO G CB  1 
ATOM   4653 C CG  . PRO C 3 48  ? 161.521 120.905 152.230 1.00 94.50  ?  55  PRO G CG  1 
ATOM   4654 C CD  . PRO C 3 48  ? 160.694 122.103 152.593 1.00 94.50  ?  55  PRO G CD  1 
ATOM   4655 N N   . ALA C 3 49  ? 158.707 120.552 148.541 1.00 90.91  ?  56  ALA G N   1 
ATOM   4656 C CA  . ALA C 3 49  ? 157.452 120.162 147.907 1.00 90.91  ?  56  ALA G CA  1 
ATOM   4657 C C   . ALA C 3 49  ? 156.885 118.872 148.483 1.00 90.91  ?  56  ALA G C   1 
ATOM   4658 O O   . ALA C 3 49  ? 155.699 118.588 148.284 1.00 90.91  ?  56  ALA G O   1 
ATOM   4659 C CB  . ALA C 3 49  ? 157.650 120.016 146.398 1.00 90.91  ?  56  ALA G CB  1 
ATOM   4660 N N   . SER C 3 50  ? 157.703 118.082 149.183 1.00 94.05  ?  57  SER G N   1 
ATOM   4661 C CA  . SER C 3 50  ? 157.206 116.852 149.789 1.00 94.05  ?  57  SER G CA  1 
ATOM   4662 C C   . SER C 3 50  ? 156.157 117.143 150.855 1.00 94.05  ?  57  SER G C   1 
ATOM   4663 O O   . SER C 3 50  ? 155.146 116.438 150.953 1.00 94.05  ?  57  SER G O   1 
ATOM   4664 C CB  . SER C 3 50  ? 158.367 116.054 150.384 1.00 94.05  ?  57  SER G CB  1 
ATOM   4665 O OG  . SER C 3 50  ? 157.893 114.995 151.197 1.00 94.05  ?  57  SER G OG  1 
ATOM   4666 N N   . GLU C 3 51  ? 156.379 118.179 151.663 1.00 91.66  ?  58  GLU G N   1 
ATOM   4667 C CA  . GLU C 3 51  ? 155.479 118.543 152.750 1.00 91.66  ?  58  GLU G CA  1 
ATOM   4668 C C   . GLU C 3 51  ? 154.691 119.814 152.440 1.00 91.66  ?  58  GLU G C   1 
ATOM   4669 O O   . GLU C 3 51  ? 154.236 120.509 153.352 1.00 91.66  ?  58  GLU G O   1 
ATOM   4670 C CB  . GLU C 3 51  ? 156.260 118.695 154.054 1.00 91.66  ?  58  GLU G CB  1 
ATOM   4671 C CG  . GLU C 3 51  ? 157.255 119.842 154.056 1.00 91.66  ?  58  GLU G CG  1 
ATOM   4672 C CD  . GLU C 3 51  ? 158.055 119.918 155.341 1.00 91.66  ?  58  GLU G CD  1 
ATOM   4673 O OE1 . GLU C 3 51  ? 157.847 119.059 156.224 1.00 91.66  ?  58  GLU G OE1 1 
ATOM   4674 O OE2 . GLU C 3 51  ? 158.892 120.836 155.469 1.00 91.66  -1 58  GLU G OE2 1 
ATOM   4675 N N   . ASN C 3 52  ? 154.515 120.123 151.156 1.00 78.74  ?  59  ASN G N   1 
ATOM   4676 C CA  . ASN C 3 52  ? 153.758 121.295 150.748 1.00 78.74  ?  59  ASN G CA  1 
ATOM   4677 C C   . ASN C 3 52  ? 152.332 120.879 150.426 1.00 78.74  ?  59  ASN G C   1 
ATOM   4678 O O   . ASN C 3 52  ? 152.119 120.141 149.452 1.00 78.74  ?  59  ASN G O   1 
ATOM   4679 C CB  . ASN C 3 52  ? 154.407 121.957 149.534 1.00 78.74  ?  59  ASN G CB  1 
ATOM   4680 C CG  . ASN C 3 52  ? 153.820 123.319 149.228 1.00 78.74  ?  59  ASN G CG  1 
ATOM   4681 O OD1 . ASN C 3 52  ? 152.926 123.795 149.926 1.00 78.74  ?  59  ASN G OD1 1 
ATOM   4682 N ND2 . ASN C 3 52  ? 154.322 123.955 148.177 1.00 78.74  ?  59  ASN G ND2 1 
ATOM   4683 N N   . PRO C 3 53  ? 151.334 121.307 151.203 1.00 70.27  ?  60  PRO G N   1 
ATOM   4684 C CA  . PRO C 3 53  ? 149.949 120.909 150.904 1.00 70.27  ?  60  PRO G CA  1 
ATOM   4685 C C   . PRO C 3 53  ? 149.456 121.379 149.548 1.00 70.27  ?  60  PRO G C   1 
ATOM   4686 O O   . PRO C 3 53  ? 148.578 120.735 148.961 1.00 70.27  ?  60  PRO G O   1 
ATOM   4687 C CB  . PRO C 3 53  ? 149.148 121.552 152.045 1.00 70.27  ?  60  PRO G CB  1 
ATOM   4688 C CG  . PRO C 3 53  ? 150.142 121.784 153.133 1.00 70.27  ?  60  PRO G CG  1 
ATOM   4689 C CD  . PRO C 3 53  ? 151.433 122.089 152.445 1.00 70.27  ?  60  PRO G CD  1 
ATOM   4690 N N   . PHE C 3 54  ? 149.992 122.482 149.030 1.00 65.78  ?  61  PHE G N   1 
ATOM   4691 C CA  . PHE C 3 54  ? 149.571 123.045 147.749 1.00 65.78  ?  61  PHE G CA  1 
ATOM   4692 C C   . PHE C 3 54  ? 150.571 122.746 146.641 1.00 65.78  ?  61  PHE G C   1 
ATOM   4693 O O   . PHE C 3 54  ? 150.825 123.591 145.780 1.00 65.78  ?  61  PHE G O   1 
ATOM   4694 C CB  . PHE C 3 54  ? 149.350 124.549 147.880 1.00 65.78  ?  61  PHE G CB  1 
ATOM   4695 C CG  . PHE C 3 54  ? 148.319 124.924 148.905 1.00 65.78  ?  61  PHE G CG  1 
ATOM   4696 C CD1 . PHE C 3 54  ? 146.979 124.986 148.567 1.00 65.78  ?  61  PHE G CD1 1 
ATOM   4697 C CD2 . PHE C 3 54  ? 148.689 125.216 150.206 1.00 65.78  ?  61  PHE G CD2 1 
ATOM   4698 C CE1 . PHE C 3 54  ? 146.029 125.330 149.506 1.00 65.78  ?  61  PHE G CE1 1 
ATOM   4699 C CE2 . PHE C 3 54  ? 147.743 125.559 151.149 1.00 65.78  ?  61  PHE G CE2 1 
ATOM   4700 C CZ  . PHE C 3 54  ? 146.412 125.617 150.799 1.00 65.78  ?  61  PHE G CZ  1 
ATOM   4701 N N   . ARG C 3 55  ? 151.156 121.552 146.646 1.00 80.64  ?  62  ARG G N   1 
ATOM   4702 C CA  . ARG C 3 55  ? 152.163 121.178 145.658 1.00 80.64  ?  62  ARG G CA  1 
ATOM   4703 C C   . ARG C 3 55  ? 151.607 121.212 144.235 1.00 80.64  ?  62  ARG G C   1 
ATOM   4704 O O   . ARG C 3 55  ? 152.292 121.641 143.306 1.00 80.64  ?  62  ARG G O   1 
ATOM   4705 C CB  . ARG C 3 55  ? 152.724 119.789 145.970 1.00 80.64  ?  62  ARG G CB  1 
ATOM   4706 C CG  . ARG C 3 55  ? 151.666 118.720 146.190 1.00 80.64  ?  62  ARG G CG  1 
ATOM   4707 C CD  . ARG C 3 55  ? 152.285 117.409 146.643 1.00 80.64  ?  62  ARG G CD  1 
ATOM   4708 N NE  . ARG C 3 55  ? 152.838 117.501 147.989 1.00 80.64  ?  62  ARG G NE  1 
ATOM   4709 C CZ  . ARG C 3 55  ? 152.238 117.037 149.076 1.00 80.64  ?  62  ARG G CZ  1 
ATOM   4710 N NH1 . ARG C 3 55  ? 151.058 116.442 149.015 1.00 80.64  1  62  ARG G NH1 1 
ATOM   4711 N NH2 . ARG C 3 55  ? 152.837 117.173 150.256 1.00 80.64  ?  62  ARG G NH2 1 
ATOM   4712 N N   . GLU C 3 56  ? 150.365 120.767 144.073 1.00 84.83  ?  63  GLU G N   1 
ATOM   4713 C CA  . GLU C 3 56  ? 149.712 120.768 142.768 1.00 84.83  ?  63  GLU G CA  1 
ATOM   4714 C CB  . GLU C 3 56  ? 150.272 119.653 141.881 1.00 84.83  ?  63  GLU G CB  1 
ATOM   4715 C CG  . GLU C 3 56  ? 150.233 118.273 142.513 1.00 84.83  ?  63  GLU G CG  1 
ATOM   4716 C CD  . GLU C 3 56  ? 149.567 117.244 141.621 1.00 84.83  ?  63  GLU G CD  1 
ATOM   4717 O OE1 . GLU C 3 56  ? 148.376 117.423 141.290 1.00 84.83  ?  63  GLU G OE1 1 
ATOM   4718 O OE2 . GLU C 3 56  ? 150.236 116.257 141.248 1.00 84.83  -1 63  GLU G OE2 1 
ATOM   4719 N N   . ASP D 4 1   ? 111.810 117.703 163.450 1.00 80.72  ?  1   ASP S N   1 
ATOM   4720 C CA  . ASP D 4 1   ? 112.958 116.853 163.739 1.00 80.72  ?  1   ASP S CA  1 
ATOM   4721 C C   . ASP D 4 1   ? 113.337 116.019 162.522 1.00 80.72  ?  1   ASP S C   1 
ATOM   4722 O O   . ASP D 4 1   ? 112.530 115.830 161.613 1.00 80.72  ?  1   ASP S O   1 
ATOM   4723 C CB  . ASP D 4 1   ? 112.665 115.942 164.930 1.00 80.72  ?  1   ASP S CB  1 
ATOM   4724 C CG  . ASP D 4 1   ? 111.343 115.213 164.793 1.00 80.72  ?  1   ASP S CG  1 
ATOM   4725 O OD1 . ASP D 4 1   ? 110.580 115.535 163.859 1.00 80.72  ?  1   ASP S OD1 1 
ATOM   4726 O OD2 . ASP D 4 1   ? 111.068 114.318 165.619 1.00 80.72  -1 1   ASP S OD2 1 
ATOM   4727 N N   . VAL D 4 2   ? 114.569 115.521 162.512 1.00 71.57  ?  2   VAL S N   1 
ATOM   4728 C CA  . VAL D 4 2   ? 115.060 114.704 161.407 1.00 71.57  ?  2   VAL S CA  1 
ATOM   4729 C C   . VAL D 4 2   ? 114.570 113.276 161.603 1.00 71.57  ?  2   VAL S C   1 
ATOM   4730 O O   . VAL D 4 2   ? 114.814 112.663 162.647 1.00 71.57  ?  2   VAL S O   1 
ATOM   4731 C CB  . VAL D 4 2   ? 116.592 114.753 161.322 1.00 71.57  ?  2   VAL S CB  1 
ATOM   4732 C CG1 . VAL D 4 2   ? 117.094 113.782 160.268 1.00 71.57  ?  2   VAL S CG1 1 
ATOM   4733 C CG2 . VAL D 4 2   ? 117.061 116.166 161.021 1.00 71.57  ?  2   VAL S CG2 1 
ATOM   4734 N N   . GLN D 4 3   ? 113.877 112.743 160.599 1.00 73.22  ?  3   GLN S N   1 
ATOM   4735 C CA  . GLN D 4 3   ? 113.394 111.374 160.668 1.00 73.22  ?  3   GLN S CA  1 
ATOM   4736 C C   . GLN D 4 3   ? 113.206 110.822 159.262 1.00 73.22  ?  3   GLN S C   1 
ATOM   4737 O O   . GLN D 4 3   ? 112.954 111.565 158.306 1.00 73.22  ?  3   GLN S O   1 
ATOM   4738 C CB  . GLN D 4 3   ? 112.089 111.274 161.467 1.00 73.22  ?  3   GLN S CB  1 
ATOM   4739 C CG  . GLN D 4 3   ? 110.849 111.708 160.714 1.00 73.22  ?  3   GLN S CG  1 
ATOM   4740 C CD  . GLN D 4 3   ? 109.571 111.319 161.426 1.00 73.22  ?  3   GLN S CD  1 
ATOM   4741 O OE1 . GLN D 4 3   ? 109.579 111.017 162.620 1.00 73.22  ?  3   GLN S OE1 1 
ATOM   4742 N NE2 . GLN D 4 3   ? 108.461 111.329 160.699 1.00 73.22  ?  3   GLN S NE2 1 
ATOM   4743 N N   . LEU D 4 4   ? 113.350 109.502 159.154 1.00 67.66  ?  4   LEU S N   1 
ATOM   4744 C CA  . LEU D 4 4   ? 113.201 108.764 157.901 1.00 67.66  ?  4   LEU S CA  1 
ATOM   4745 C C   . LEU D 4 4   ? 112.208 107.637 158.163 1.00 67.66  ?  4   LEU S C   1 
ATOM   4746 O O   . LEU D 4 4   ? 112.588 106.576 158.665 1.00 67.66  ?  4   LEU S O   1 
ATOM   4747 C CB  . LEU D 4 4   ? 114.542 108.216 157.421 1.00 67.66  ?  4   LEU S CB  1 
ATOM   4748 C CG  . LEU D 4 4   ? 115.630 109.207 157.010 1.00 67.66  ?  4   LEU S CG  1 
ATOM   4749 C CD1 . LEU D 4 4   ? 116.998 108.663 157.362 1.00 67.66  ?  4   LEU S CD1 1 
ATOM   4750 C CD2 . LEU D 4 4   ? 115.552 109.474 155.526 1.00 67.66  ?  4   LEU S CD2 1 
ATOM   4751 N N   . VAL D 4 5   ? 110.940 107.860 157.829 1.00 74.25  ?  5   VAL S N   1 
ATOM   4752 C CA  . VAL D 4 5   ? 109.890 106.872 158.051 1.00 74.25  ?  5   VAL S CA  1 
ATOM   4753 C C   . VAL D 4 5   ? 109.678 106.110 156.754 1.00 74.25  ?  5   VAL S C   1 
ATOM   4754 O O   . VAL D 4 5   ? 109.431 106.713 155.705 1.00 74.25  ?  5   VAL S O   1 
ATOM   4755 C CB  . VAL D 4 5   ? 108.586 107.535 158.525 1.00 74.25  ?  5   VAL S CB  1 
ATOM   4756 C CG1 . VAL D 4 5   ? 107.441 106.537 158.484 1.00 74.25  ?  5   VAL S CG1 1 
ATOM   4757 C CG2 . VAL D 4 5   ? 108.760 108.093 159.926 1.00 74.25  ?  5   VAL S CG2 1 
ATOM   4758 N N   . GLU D 4 6   ? 109.767 104.788 156.818 1.00 76.62  ?  6   GLU S N   1 
ATOM   4759 C CA  . GLU D 4 6   ? 109.770 103.968 155.619 1.00 76.62  ?  6   GLU S CA  1 
ATOM   4760 C C   . GLU D 4 6   ? 108.811 102.796 155.755 1.00 76.62  ?  6   GLU S C   1 
ATOM   4761 O O   . GLU D 4 6   ? 108.459 102.369 156.858 1.00 76.62  ?  6   GLU S O   1 
ATOM   4762 C CB  . GLU D 4 6   ? 111.183 103.475 155.302 1.00 76.62  ?  6   GLU S CB  1 
ATOM   4763 C CG  . GLU D 4 6   ? 111.754 102.542 156.336 1.00 76.62  ?  6   GLU S CG  1 
ATOM   4764 C CD  . GLU D 4 6   ? 113.165 102.138 156.006 1.00 76.62  ?  6   GLU S CD  1 
ATOM   4765 O OE1 . GLU D 4 6   ? 113.685 102.609 154.978 1.00 76.62  ?  6   GLU S OE1 1 
ATOM   4766 O OE2 . GLU D 4 6   ? 113.767 101.375 156.782 1.00 76.62  -1 6   GLU S OE2 1 
ATOM   4767 N N   . SER D 4 7   ? 108.388 102.289 154.601 1.00 79.50  ?  7   SER S N   1 
ATOM   4768 C CA  . SER D 4 7   ? 107.428 101.196 154.528 1.00 79.50  ?  7   SER S CA  1 
ATOM   4769 C C   . SER D 4 7   ? 107.658 100.427 153.235 1.00 79.50  ?  7   SER S C   1 
ATOM   4770 O O   . SER D 4 7   ? 108.488 100.801 152.401 1.00 79.50  ?  7   SER S O   1 
ATOM   4771 C CB  . SER D 4 7   ? 105.989 101.712 154.612 1.00 79.50  ?  7   SER S CB  1 
ATOM   4772 O OG  . SER D 4 7   ? 105.766 102.753 153.676 1.00 79.50  ?  7   SER S OG  1 
ATOM   4773 N N   . GLY D 4 8   ? 106.909 99.337  153.082 1.00 82.64  ?  8   GLY S N   1 
ATOM   4774 C CA  . GLY D 4 8   ? 107.007 98.507  151.898 1.00 82.64  ?  8   GLY S CA  1 
ATOM   4775 C C   . GLY D 4 8   ? 107.369 97.067  152.197 1.00 82.64  ?  8   GLY S C   1 
ATOM   4776 O O   . GLY D 4 8   ? 107.585 96.272  151.277 1.00 82.64  ?  8   GLY S O   1 
ATOM   4777 N N   . GLY D 4 9   ? 107.435 96.716  153.477 1.00 85.51  ?  9   GLY S N   1 
ATOM   4778 C CA  . GLY D 4 9   ? 107.773 95.370  153.886 1.00 85.51  ?  9   GLY S CA  1 
ATOM   4779 C C   . GLY D 4 9   ? 106.570 94.446  153.875 1.00 85.51  ?  9   GLY S C   1 
ATOM   4780 O O   . GLY D 4 9   ? 105.467 94.801  153.457 1.00 85.51  ?  9   GLY S O   1 
ATOM   4781 N N   . GLY D 4 10  ? 106.802 93.223  154.349 1.00 88.78  ?  10  GLY S N   1 
ATOM   4782 C CA  . GLY D 4 10  ? 105.776 92.211  154.454 1.00 88.78  ?  10  GLY S CA  1 
ATOM   4783 C C   . GLY D 4 10  ? 106.246 90.890  153.890 1.00 88.78  ?  10  GLY S C   1 
ATOM   4784 O O   . GLY D 4 10  ? 107.442 90.662  153.676 1.00 88.78  ?  10  GLY S O   1 
ATOM   4785 N N   . LEU D 4 11  ? 105.284 90.000  153.650 1.00 92.40  ?  11  LEU S N   1 
ATOM   4786 C CA  . LEU D 4 11  ? 105.558 88.674  153.111 1.00 92.40  ?  11  LEU S CA  1 
ATOM   4787 C C   . LEU D 4 11  ? 105.549 88.722  151.589 1.00 92.40  ?  11  LEU S C   1 
ATOM   4788 O O   . LEU D 4 11  ? 104.636 89.293  150.984 1.00 92.40  ?  11  LEU S O   1 
ATOM   4789 C CB  . LEU D 4 11  ? 104.528 87.661  153.614 1.00 92.40  ?  11  LEU S CB  1 
ATOM   4790 C CG  . LEU D 4 11  ? 104.536 87.362  155.113 1.00 92.40  ?  11  LEU S CG  1 
ATOM   4791 C CD1 . LEU D 4 11  ? 103.375 86.451  155.485 1.00 92.40  ?  11  LEU S CD1 1 
ATOM   4792 C CD2 . LEU D 4 11  ? 105.861 86.746  155.528 1.00 92.40  ?  11  LEU S CD2 1 
ATOM   4793 N N   . VAL D 4 12  ? 106.568 88.123  150.977 1.00 93.32  ?  12  VAL S N   1 
ATOM   4794 C CA  . VAL D 4 12  ? 106.744 88.146  149.531 1.00 93.32  ?  12  VAL S CA  1 
ATOM   4795 C C   . VAL D 4 12  ? 106.973 86.720  149.050 1.00 93.32  ?  12  VAL S C   1 
ATOM   4796 O O   . VAL D 4 12  ? 107.787 85.990  149.626 1.00 93.32  ?  12  VAL S O   1 
ATOM   4797 C CB  . VAL D 4 12  ? 107.922 89.046  149.113 1.00 93.32  ?  12  VAL S CB  1 
ATOM   4798 C CG1 . VAL D 4 12  ? 108.066 89.072  147.597 1.00 93.32  ?  12  VAL S CG1 1 
ATOM   4799 C CG2 . VAL D 4 12  ? 107.759 90.446  149.682 1.00 93.32  ?  12  VAL S CG2 1 
ATOM   4800 N N   . GLN D 4 13  ? 106.253 86.324  148.005 1.00 96.78  ?  13  GLN S N   1 
ATOM   4801 C CA  . GLN D 4 13  ? 106.521 85.047  147.371 1.00 96.78  ?  13  GLN S CA  1 
ATOM   4802 C C   . GLN D 4 13  ? 107.830 85.125  146.586 1.00 96.78  ?  13  GLN S C   1 
ATOM   4803 O O   . GLN D 4 13  ? 108.171 86.178  146.040 1.00 96.78  ?  13  GLN S O   1 
ATOM   4804 C CB  . GLN D 4 13  ? 105.376 84.657  146.442 1.00 96.78  ?  13  GLN S CB  1 
ATOM   4805 C CG  . GLN D 4 13  ? 104.064 84.404  147.162 1.00 96.78  ?  13  GLN S CG  1 
ATOM   4806 C CD  . GLN D 4 13  ? 104.149 83.243  148.133 1.00 96.78  ?  13  GLN S CD  1 
ATOM   4807 O OE1 . GLN D 4 13  ? 104.126 83.434  149.349 1.00 96.78  ?  13  GLN S OE1 1 
ATOM   4808 N NE2 . GLN D 4 13  ? 104.252 82.032  147.600 1.00 96.78  ?  13  GLN S NE2 1 
ATOM   4809 N N   . PRO D 4 14  ? 108.588 84.031  146.527 1.00 94.55  ?  14  PRO S N   1 
ATOM   4810 C CA  . PRO D 4 14  ? 109.853 84.057  145.783 1.00 94.55  ?  14  PRO S CA  1 
ATOM   4811 C C   . PRO D 4 14  ? 109.625 84.370  144.312 1.00 94.55  ?  14  PRO S C   1 
ATOM   4812 O O   . PRO D 4 14  ? 108.645 83.931  143.708 1.00 94.55  ?  14  PRO S O   1 
ATOM   4813 C CB  . PRO D 4 14  ? 110.411 82.643  145.979 1.00 94.55  ?  14  PRO S CB  1 
ATOM   4814 C CG  . PRO D 4 14  ? 109.743 82.136  147.210 1.00 94.55  ?  14  PRO S CG  1 
ATOM   4815 C CD  . PRO D 4 14  ? 108.375 82.745  147.210 1.00 94.55  ?  14  PRO S CD  1 
ATOM   4816 N N   . GLY D 4 15  ? 110.547 85.139  143.739 1.00 90.01  ?  15  GLY S N   1 
ATOM   4817 C CA  . GLY D 4 15  ? 110.452 85.546  142.355 1.00 90.01  ?  15  GLY S CA  1 
ATOM   4818 C C   . GLY D 4 15  ? 109.569 86.745  142.093 1.00 90.01  ?  15  GLY S C   1 
ATOM   4819 O O   . GLY D 4 15  ? 109.396 87.120  140.927 1.00 90.01  ?  15  GLY S O   1 
ATOM   4820 N N   . GLY D 4 16  ? 109.009 87.359  143.129 1.00 89.21  ?  16  GLY S N   1 
ATOM   4821 C CA  . GLY D 4 16  ? 108.145 88.510  142.979 1.00 89.21  ?  16  GLY S CA  1 
ATOM   4822 C C   . GLY D 4 16  ? 108.915 89.813  142.945 1.00 89.21  ?  16  GLY S C   1 
ATOM   4823 O O   . GLY D 4 16  ? 110.132 89.846  142.750 1.00 89.21  ?  16  GLY S O   1 
ATOM   4824 N N   . SER D 4 17  ? 108.181 90.908  143.134 1.00 87.48  ?  17  SER S N   1 
ATOM   4825 C CA  . SER D 4 17  ? 108.775 92.236  143.126 1.00 87.48  ?  17  SER S CA  1 
ATOM   4826 C C   . SER D 4 17  ? 108.037 93.119  144.120 1.00 87.48  ?  17  SER S C   1 
ATOM   4827 O O   . SER D 4 17  ? 106.819 93.009  144.283 1.00 87.48  ?  17  SER S O   1 
ATOM   4828 C CB  . SER D 4 17  ? 108.733 92.858  141.727 1.00 87.48  ?  17  SER S CB  1 
ATOM   4829 N N   . ARG D 4 18  ? 108.786 94.006  144.773 1.00 86.35  ?  18  ARG S N   1 
ATOM   4830 C CA  . ARG D 4 18  ? 108.226 94.917  145.763 1.00 86.35  ?  18  ARG S CA  1 
ATOM   4831 C C   . ARG D 4 18  ? 108.940 96.257  145.698 1.00 86.35  ?  18  ARG S C   1 
ATOM   4832 O O   . ARG D 4 18  ? 110.107 96.344  145.307 1.00 86.35  ?  18  ARG S O   1 
ATOM   4833 C CB  . ARG D 4 18  ? 108.319 94.360  147.189 1.00 86.35  ?  18  ARG S CB  1 
ATOM   4834 C CG  . ARG D 4 18  ? 107.520 93.097  147.426 1.00 86.35  ?  18  ARG S CG  1 
ATOM   4835 C CD  . ARG D 4 18  ? 106.026 93.371  147.348 1.00 86.35  ?  18  ARG S CD  1 
ATOM   4836 N NE  . ARG D 4 18  ? 105.591 94.334  148.351 1.00 86.35  ?  18  ARG S NE  1 
ATOM   4837 C CZ  . ARG D 4 18  ? 105.248 94.017  149.592 1.00 86.35  ?  18  ARG S CZ  1 
ATOM   4838 N NH1 . ARG D 4 18  ? 105.265 92.763  150.014 1.00 86.35  1  18  ARG S NH1 1 
ATOM   4839 N NH2 . ARG D 4 18  ? 104.876 94.980  150.430 1.00 86.35  ?  18  ARG S NH2 1 
ATOM   4840 N N   . LYS D 4 19  ? 108.228 97.300  146.107 1.00 80.21  ?  19  LYS S N   1 
ATOM   4841 C CA  . LYS D 4 19  ? 108.737 98.664  146.090 1.00 80.21  ?  19  LYS S CA  1 
ATOM   4842 C C   . LYS D 4 19  ? 108.774 99.179  147.523 1.00 80.21  ?  19  LYS S C   1 
ATOM   4843 O O   . LYS D 4 19  ? 107.739 99.227  148.195 1.00 80.21  ?  19  LYS S O   1 
ATOM   4844 C CB  . LYS D 4 19  ? 107.856 99.548  145.208 1.00 80.21  ?  19  LYS S CB  1 
ATOM   4845 C CG  . LYS D 4 19  ? 108.313 100.985 145.054 1.00 80.21  ?  19  LYS S CG  1 
ATOM   4846 C CD  . LYS D 4 19  ? 107.410 101.707 144.066 1.00 80.21  ?  19  LYS S CD  1 
ATOM   4847 C CE  . LYS D 4 19  ? 107.727 103.186 143.977 1.00 80.21  ?  19  LYS S CE  1 
ATOM   4848 N NZ  . LYS D 4 19  ? 109.078 103.418 143.399 1.00 80.21  1  19  LYS S NZ  1 
ATOM   4849 N N   . LEU D 4 20  ? 109.961 99.559  147.987 1.00 73.55  ?  20  LEU S N   1 
ATOM   4850 C CA  . LEU D 4 20  ? 110.152 100.074 149.336 1.00 73.55  ?  20  LEU S CA  1 
ATOM   4851 C C   . LEU D 4 20  ? 110.295 101.588 149.276 1.00 73.55  ?  20  LEU S C   1 
ATOM   4852 O O   . LEU D 4 20  ? 111.074 102.108 148.470 1.00 73.55  ?  20  LEU S O   1 
ATOM   4853 C CB  . LEU D 4 20  ? 111.386 99.452  149.990 1.00 73.55  ?  20  LEU S CB  1 
ATOM   4854 C CG  . LEU D 4 20  ? 111.161 98.233  150.884 1.00 73.55  ?  20  LEU S CG  1 
ATOM   4855 C CD1 . LEU D 4 20  ? 110.747 97.027  150.059 1.00 73.55  ?  20  LEU S CD1 1 
ATOM   4856 C CD2 . LEU D 4 20  ? 112.413 97.930  151.688 1.00 73.55  ?  20  LEU S CD2 1 
ATOM   4857 N N   . SER D 4 21  ? 109.547 102.288 150.125 1.00 74.69  ?  21  SER S N   1 
ATOM   4858 C CA  . SER D 4 21  ? 109.528 103.743 150.137 1.00 74.69  ?  21  SER S CA  1 
ATOM   4859 C C   . SER D 4 21  ? 110.077 104.257 151.459 1.00 74.69  ?  21  SER S C   1 
ATOM   4860 O O   . SER D 4 21  ? 109.865 103.646 152.509 1.00 74.69  ?  21  SER S O   1 
ATOM   4861 C CB  . SER D 4 21  ? 108.110 104.278 149.916 1.00 74.69  ?  21  SER S CB  1 
ATOM   4862 O OG  . SER D 4 21  ? 107.667 104.014 148.596 1.00 74.69  ?  21  SER S OG  1 
ATOM   4863 N N   . CYS D 4 22  ? 110.788 105.382 151.392 1.00 74.21  ?  22  CYS S N   1 
ATOM   4864 C CA  . CYS D 4 22  ? 111.402 106.026 152.551 1.00 74.21  ?  22  CYS S CA  1 
ATOM   4865 C C   . CYS D 4 22  ? 111.119 107.519 152.470 1.00 74.21  ?  22  CYS S C   1 
ATOM   4866 O O   . CYS D 4 22  ? 111.753 108.227 151.682 1.00 74.21  ?  22  CYS S O   1 
ATOM   4867 C CB  . CYS D 4 22  ? 112.909 105.760 152.589 1.00 74.21  ?  22  CYS S CB  1 
ATOM   4868 S SG  . CYS D 4 22  ? 113.825 106.666 153.864 1.00 74.21  ?  22  CYS S SG  1 
ATOM   4869 N N   . SER D 4 23  ? 110.159 107.995 153.260 1.00 74.49  ?  23  SER S N   1 
ATOM   4870 C CA  . SER D 4 23  ? 109.831 109.410 153.316 1.00 74.49  ?  23  SER S CA  1 
ATOM   4871 C C   . SER D 4 23  ? 110.690 110.090 154.374 1.00 74.49  ?  23  SER S C   1 
ATOM   4872 O O   . SER D 4 23  ? 110.714 109.667 155.536 1.00 74.49  ?  23  SER S O   1 
ATOM   4873 C CB  . SER D 4 23  ? 108.348 109.609 153.628 1.00 74.49  ?  23  SER S CB  1 
ATOM   4874 O OG  . SER D 4 23  ? 107.536 109.068 152.601 1.00 74.49  ?  23  SER S OG  1 
ATOM   4875 N N   . ALA D 4 24  ? 111.386 111.146 153.968 1.00 71.63  ?  24  ALA S N   1 
ATOM   4876 C CA  . ALA D 4 24  ? 112.296 111.878 154.836 1.00 71.63  ?  24  ALA S CA  1 
ATOM   4877 C C   . ALA D 4 24  ? 111.678 113.215 155.215 1.00 71.63  ?  24  ALA S C   1 
ATOM   4878 O O   . ALA D 4 24  ? 111.164 113.931 154.349 1.00 71.63  ?  24  ALA S O   1 
ATOM   4879 C CB  . ALA D 4 24  ? 113.639 112.101 154.143 1.00 71.63  ?  24  ALA S CB  1 
ATOM   4880 N N   . SER D 4 25  ? 111.728 113.551 156.502 1.00 73.33  ?  25  SER S N   1 
ATOM   4881 C CA  . SER D 4 25  ? 111.219 114.836 156.957 1.00 73.33  ?  25  SER S CA  1 
ATOM   4882 C C   . SER D 4 25  ? 112.173 115.430 157.981 1.00 73.33  ?  25  SER S C   1 
ATOM   4883 O O   . SER D 4 25  ? 112.722 114.712 158.820 1.00 73.33  ?  25  SER S O   1 
ATOM   4884 C CB  . SER D 4 25  ? 109.815 114.702 157.559 1.00 73.33  ?  25  SER S CB  1 
ATOM   4885 O OG  . SER D 4 25  ? 109.835 113.923 158.739 1.00 73.33  ?  25  SER S OG  1 
ATOM   4886 N N   . GLY D 4 26  ? 112.365 116.742 157.904 1.00 70.01  ?  26  GLY S N   1 
ATOM   4887 C CA  . GLY D 4 26  ? 113.185 117.454 158.858 1.00 70.01  ?  26  GLY S CA  1 
ATOM   4888 C C   . GLY D 4 26  ? 114.583 117.807 158.406 1.00 70.01  ?  26  GLY S C   1 
ATOM   4889 O O   . GLY D 4 26  ? 115.354 118.339 159.212 1.00 70.01  ?  26  GLY S O   1 
ATOM   4890 N N   . PHE D 4 27  ? 114.940 117.532 157.153 1.00 64.65  ?  27  PHE S N   1 
ATOM   4891 C CA  . PHE D 4 27  ? 116.260 117.881 156.650 1.00 64.65  ?  27  PHE S CA  1 
ATOM   4892 C C   . PHE D 4 27  ? 116.196 118.026 155.137 1.00 64.65  ?  27  PHE S C   1 
ATOM   4893 O O   . PHE D 4 27  ? 115.227 117.619 154.491 1.00 64.65  ?  27  PHE S O   1 
ATOM   4894 C CB  . PHE D 4 27  ? 117.315 116.846 157.063 1.00 64.65  ?  27  PHE S CB  1 
ATOM   4895 C CG  . PHE D 4 27  ? 117.166 115.513 156.387 1.00 64.65  ?  27  PHE S CG  1 
ATOM   4896 C CD1 . PHE D 4 27  ? 116.299 114.560 156.890 1.00 64.65  ?  27  PHE S CD1 1 
ATOM   4897 C CD2 . PHE D 4 27  ? 117.910 115.205 155.261 1.00 64.65  ?  27  PHE S CD2 1 
ATOM   4898 C CE1 . PHE D 4 27  ? 116.167 113.333 156.276 1.00 64.65  ?  27  PHE S CE1 1 
ATOM   4899 C CE2 . PHE D 4 27  ? 117.780 113.979 154.643 1.00 64.65  ?  27  PHE S CE2 1 
ATOM   4900 C CZ  . PHE D 4 27  ? 116.909 113.042 155.151 1.00 64.65  ?  27  PHE S CZ  1 
ATOM   4901 N N   . ALA D 4 28  ? 117.248 118.620 154.576 1.00 65.86  ?  28  ALA S N   1 
ATOM   4902 C CA  . ALA D 4 28  ? 117.330 118.846 153.139 1.00 65.86  ?  28  ALA S CA  1 
ATOM   4903 C C   . ALA D 4 28  ? 117.616 117.544 152.405 1.00 65.86  ?  28  ALA S C   1 
ATOM   4904 O O   . ALA D 4 28  ? 118.778 117.178 152.205 1.00 65.86  ?  28  ALA S O   1 
ATOM   4905 C CB  . ALA D 4 28  ? 118.406 119.885 152.820 1.00 65.86  ?  28  ALA S CB  1 
ATOM   4906 N N   . PHE D 4 29  ? 116.556 116.842 151.997 1.00 66.28  ?  29  PHE S N   1 
ATOM   4907 C CA  . PHE D 4 29  ? 116.718 115.545 151.347 1.00 66.28  ?  29  PHE S CA  1 
ATOM   4908 C C   . PHE D 4 29  ? 117.481 115.656 150.034 1.00 66.28  ?  29  PHE S C   1 
ATOM   4909 O O   . PHE D 4 29  ? 118.164 114.708 149.633 1.00 66.28  ?  29  PHE S O   1 
ATOM   4910 C CB  . PHE D 4 29  ? 115.345 114.913 151.114 1.00 66.28  ?  29  PHE S CB  1 
ATOM   4911 C CG  . PHE D 4 29  ? 115.396 113.564 150.458 1.00 66.28  ?  29  PHE S CG  1 
ATOM   4912 C CD1 . PHE D 4 29  ? 115.587 112.420 151.212 1.00 66.28  ?  29  PHE S CD1 1 
ATOM   4913 C CD2 . PHE D 4 29  ? 115.240 113.437 149.088 1.00 66.28  ?  29  PHE S CD2 1 
ATOM   4914 C CE1 . PHE D 4 29  ? 115.627 111.179 150.613 1.00 66.28  ?  29  PHE S CE1 1 
ATOM   4915 C CE2 . PHE D 4 29  ? 115.283 112.199 148.485 1.00 66.28  ?  29  PHE S CE2 1 
ATOM   4916 C CZ  . PHE D 4 29  ? 115.477 111.068 149.248 1.00 66.28  ?  29  PHE S CZ  1 
ATOM   4917 N N   . SER D 4 30  ? 117.382 116.799 149.353 1.00 68.26  ?  30  SER S N   1 
ATOM   4918 C CA  . SER D 4 30  ? 118.017 116.935 148.047 1.00 68.26  ?  30  SER S CA  1 
ATOM   4919 C C   . SER D 4 30  ? 119.537 116.965 148.149 1.00 68.26  ?  30  SER S C   1 
ATOM   4920 O O   . SER D 4 30  ? 120.226 116.598 147.191 1.00 68.26  ?  30  SER S O   1 
ATOM   4921 C CB  . SER D 4 30  ? 117.512 118.196 147.348 1.00 68.26  ?  30  SER S CB  1 
ATOM   4922 O OG  . SER D 4 30  ? 116.097 118.210 147.284 1.00 68.26  ?  30  SER S OG  1 
ATOM   4923 N N   . SER D 4 31  ? 120.076 117.393 149.287 1.00 64.39  ?  31  SER S N   1 
ATOM   4924 C CA  . SER D 4 31  ? 121.515 117.544 149.454 1.00 64.39  ?  31  SER S CA  1 
ATOM   4925 C C   . SER D 4 31  ? 122.183 116.322 150.070 1.00 64.39  ?  31  SER S C   1 
ATOM   4926 O O   . SER D 4 31  ? 123.399 116.343 150.282 1.00 64.39  ?  31  SER S O   1 
ATOM   4927 C CB  . SER D 4 31  ? 121.817 118.775 150.313 1.00 64.39  ?  31  SER S CB  1 
ATOM   4928 O OG  . SER D 4 31  ? 121.339 119.956 149.695 1.00 64.39  ?  31  SER S OG  1 
ATOM   4929 N N   . PHE D 4 32  ? 121.432 115.264 150.358 1.00 59.22  ?  32  PHE S N   1 
ATOM   4930 C CA  . PHE D 4 32  ? 121.955 114.086 151.035 1.00 59.22  ?  32  PHE S CA  1 
ATOM   4931 C C   . PHE D 4 32  ? 121.940 112.889 150.096 1.00 59.22  ?  32  PHE S C   1 
ATOM   4932 O O   . PHE D 4 32  ? 120.915 112.597 149.473 1.00 59.22  ?  32  PHE S O   1 
ATOM   4933 C CB  . PHE D 4 32  ? 121.135 113.763 152.285 1.00 59.22  ?  32  PHE S CB  1 
ATOM   4934 C CG  . PHE D 4 32  ? 121.542 114.542 153.499 1.00 59.22  ?  32  PHE S CG  1 
ATOM   4935 C CD1 . PHE D 4 32  ? 121.202 115.875 153.629 1.00 59.22  ?  32  PHE S CD1 1 
ATOM   4936 C CD2 . PHE D 4 32  ? 122.256 113.936 154.516 1.00 59.22  ?  32  PHE S CD2 1 
ATOM   4937 C CE1 . PHE D 4 32  ? 121.572 116.590 154.745 1.00 59.22  ?  32  PHE S CE1 1 
ATOM   4938 C CE2 . PHE D 4 32  ? 122.629 114.648 155.636 1.00 59.22  ?  32  PHE S CE2 1 
ATOM   4939 C CZ  . PHE D 4 32  ? 122.286 115.976 155.750 1.00 59.22  ?  32  PHE S CZ  1 
ATOM   4940 N N   . GLY D 4 33  ? 123.076 112.204 149.995 1.00 56.96  ?  33  GLY S N   1 
ATOM   4941 C CA  . GLY D 4 33  ? 123.075 110.881 149.408 1.00 56.96  ?  33  GLY S CA  1 
ATOM   4942 C C   . GLY D 4 33  ? 122.359 109.894 150.308 1.00 56.96  ?  33  GLY S C   1 
ATOM   4943 O O   . GLY D 4 33  ? 122.339 110.033 151.530 1.00 56.96  ?  33  GLY S O   1 
ATOM   4944 N N   . MET D 4 34  ? 121.741 108.888 149.699 1.00 56.63  ?  34  MET S N   1 
ATOM   4945 C CA  . MET D 4 34  ? 120.892 107.970 150.445 1.00 56.63  ?  34  MET S CA  1 
ATOM   4946 C C   . MET D 4 34  ? 121.314 106.533 150.188 1.00 56.63  ?  34  MET S C   1 
ATOM   4947 O O   . MET D 4 34  ? 121.481 106.124 149.035 1.00 56.63  ?  34  MET S O   1 
ATOM   4948 C CB  . MET D 4 34  ? 119.419 108.171 150.085 1.00 56.63  ?  34  MET S CB  1 
ATOM   4949 C CG  . MET D 4 34  ? 118.965 109.617 150.188 1.00 56.63  ?  34  MET S CG  1 
ATOM   4950 S SD  . MET D 4 34  ? 118.671 110.149 151.885 1.00 56.63  ?  34  MET S SD  1 
ATOM   4951 C CE  . MET D 4 34  ? 117.823 108.722 152.545 1.00 56.63  ?  34  MET S CE  1 
ATOM   4952 N N   . HIS D 4 35  ? 121.470 105.772 151.266 1.00 54.12  ?  35  HIS S N   1 
ATOM   4953 C CA  . HIS D 4 35  ? 121.863 104.374 151.211 1.00 54.12  ?  35  HIS S CA  1 
ATOM   4954 C C   . HIS D 4 35  ? 120.721 103.487 151.685 1.00 54.12  ?  35  HIS S C   1 
ATOM   4955 O O   . HIS D 4 35  ? 120.010 103.822 152.638 1.00 54.12  ?  35  HIS S O   1 
ATOM   4956 C CB  . HIS D 4 35  ? 123.096 104.109 152.079 1.00 54.12  ?  35  HIS S CB  1 
ATOM   4957 C CG  . HIS D 4 35  ? 124.299 104.914 151.698 1.00 54.12  ?  35  HIS S CG  1 
ATOM   4958 N ND1 . HIS D 4 35  ? 125.391 104.362 151.065 1.00 54.12  ?  35  HIS S ND1 1 
ATOM   4959 C CD2 . HIS D 4 35  ? 124.589 106.224 151.874 1.00 54.12  ?  35  HIS S CD2 1 
ATOM   4960 C CE1 . HIS D 4 35  ? 126.299 105.299 150.862 1.00 54.12  ?  35  HIS S CE1 1 
ATOM   4961 N NE2 . HIS D 4 35  ? 125.837 106.439 151.342 1.00 54.12  ?  35  HIS S NE2 1 
ATOM   4962 N N   . TRP D 4 36  ? 120.551 102.359 151.008 1.00 59.69  ?  36  TRP S N   1 
ATOM   4963 C CA  . TRP D 4 36  ? 119.715 101.265 151.477 1.00 59.69  ?  36  TRP S CA  1 
ATOM   4964 C C   . TRP D 4 36  ? 120.641 100.187 152.018 1.00 59.69  ?  36  TRP S C   1 
ATOM   4965 O O   . TRP D 4 36  ? 121.498 99.683  151.280 1.00 59.69  ?  36  TRP S O   1 
ATOM   4966 C CB  . TRP D 4 36  ? 118.848 100.706 150.350 1.00 59.69  ?  36  TRP S CB  1 
ATOM   4967 C CG  . TRP D 4 36  ? 117.558 101.424 150.152 1.00 59.69  ?  36  TRP S CG  1 
ATOM   4968 C CD1 . TRP D 4 36  ? 117.266 102.327 149.176 1.00 59.69  ?  36  TRP S CD1 1 
ATOM   4969 C CD2 . TRP D 4 36  ? 116.375 101.294 150.947 1.00 59.69  ?  36  TRP S CD2 1 
ATOM   4970 N NE1 . TRP D 4 36  ? 115.975 102.770 149.313 1.00 59.69  ?  36  TRP S NE1 1 
ATOM   4971 C CE2 . TRP D 4 36  ? 115.406 102.152 150.394 1.00 59.69  ?  36  TRP S CE2 1 
ATOM   4972 C CE3 . TRP D 4 36  ? 116.041 100.537 152.073 1.00 59.69  ?  36  TRP S CE3 1 
ATOM   4973 C CZ2 . TRP D 4 36  ? 114.128 102.275 150.928 1.00 59.69  ?  36  TRP S CZ2 1 
ATOM   4974 C CZ3 . TRP D 4 36  ? 114.772 100.660 152.601 1.00 59.69  ?  36  TRP S CZ3 1 
ATOM   4975 C CH2 . TRP D 4 36  ? 113.831 101.522 152.029 1.00 59.69  ?  36  TRP S CH2 1 
ATOM   4976 N N   . VAL D 4 37  ? 120.473 99.843  153.295 1.00 57.42  ?  37  VAL S N   1 
ATOM   4977 C CA  . VAL D 4 37  ? 121.337 98.880  153.973 1.00 57.42  ?  37  VAL S CA  1 
ATOM   4978 C C   . VAL D 4 37  ? 120.453 97.860  154.675 1.00 57.42  ?  37  VAL S C   1 
ATOM   4979 O O   . VAL D 4 37  ? 119.635 98.229  155.522 1.00 57.42  ?  37  VAL S O   1 
ATOM   4980 C CB  . VAL D 4 37  ? 122.272 99.565  154.985 1.00 57.42  ?  37  VAL S CB  1 
ATOM   4981 C CG1 . VAL D 4 37  ? 122.917 98.536  155.895 1.00 57.42  ?  37  VAL S CG1 1 
ATOM   4982 C CG2 . VAL D 4 37  ? 123.327 100.388 154.267 1.00 57.42  ?  37  VAL S CG2 1 
ATOM   4983 N N   . ARG D 4 38  ? 120.616 96.585  154.343 1.00 67.61  ?  38  ARG S N   1 
ATOM   4984 C CA  . ARG D 4 38  ? 119.782 95.558  154.947 1.00 67.61  ?  38  ARG S CA  1 
ATOM   4985 C C   . ARG D 4 38  ? 120.546 94.813  156.031 1.00 67.61  ?  38  ARG S C   1 
ATOM   4986 O O   . ARG D 4 38  ? 121.774 94.708  155.998 1.00 67.61  ?  38  ARG S O   1 
ATOM   4987 C CB  . ARG D 4 38  ? 119.275 94.559  153.905 1.00 67.61  ?  38  ARG S CB  1 
ATOM   4988 C CG  . ARG D 4 38  ? 120.352 93.719  153.255 1.00 67.61  ?  38  ARG S CG  1 
ATOM   4989 C CD  . ARG D 4 38  ? 119.751 92.811  152.198 1.00 67.61  ?  38  ARG S CD  1 
ATOM   4990 N NE  . ARG D 4 38  ? 120.755 91.981  151.547 1.00 67.61  ?  38  ARG S NE  1 
ATOM   4991 C CZ  . ARG D 4 38  ? 120.489 91.095  150.598 1.00 67.61  ?  38  ARG S CZ  1 
ATOM   4992 N NH1 . ARG D 4 38  ? 119.256 90.904  150.158 1.00 67.61  1  38  ARG S NH1 1 
ATOM   4993 N NH2 . ARG D 4 38  ? 121.485 90.387  150.073 1.00 67.61  ?  38  ARG S NH2 1 
ATOM   4994 N N   . GLN D 4 39  ? 119.797 94.299  157.002 1.00 72.64  ?  39  GLN S N   1 
ATOM   4995 C CA  . GLN D 4 39  ? 120.333 93.445  158.050 1.00 72.64  ?  39  GLN S CA  1 
ATOM   4996 C C   . GLN D 4 39  ? 119.487 92.186  158.105 1.00 72.64  ?  39  GLN S C   1 
ATOM   4997 O O   . GLN D 4 39  ? 118.281 92.258  158.363 1.00 72.64  ?  39  GLN S O   1 
ATOM   4998 C CB  . GLN D 4 39  ? 120.332 94.155  159.406 1.00 72.64  ?  39  GLN S CB  1 
ATOM   4999 C CG  . GLN D 4 39  ? 120.591 93.233  160.583 1.00 72.64  ?  39  GLN S CG  1 
ATOM   5000 C CD  . GLN D 4 39  ? 120.410 93.927  161.915 1.00 72.64  ?  39  GLN S CD  1 
ATOM   5001 O OE1 . GLN D 4 39  ? 119.357 94.500  162.192 1.00 72.64  ?  39  GLN S OE1 1 
ATOM   5002 N NE2 . GLN D 4 39  ? 121.439 93.878  162.752 1.00 72.64  ?  39  GLN S NE2 1 
ATOM   5003 N N   . ALA D 4 40  ? 120.110 91.042  157.844 1.00 82.16  ?  40  ALA S N   1 
ATOM   5004 C CA  . ALA D 4 40  ? 119.414 89.777  157.944 1.00 82.16  ?  40  ALA S CA  1 
ATOM   5005 C C   . ALA D 4 40  ? 119.078 89.493  159.407 1.00 82.16  ?  40  ALA S C   1 
ATOM   5006 O O   . ALA D 4 40  ? 119.685 90.073  160.310 1.00 82.16  ?  40  ALA S O   1 
ATOM   5007 C CB  . ALA D 4 40  ? 120.266 88.660  157.349 1.00 82.16  ?  40  ALA S CB  1 
ATOM   5008 N N   . PRO D 4 41  ? 118.081 88.618  159.663 1.00 86.50  ?  41  PRO S N   1 
ATOM   5009 C CA  . PRO D 4 41  ? 117.596 88.399  161.036 1.00 86.50  ?  41  PRO S CA  1 
ATOM   5010 C C   . PRO D 4 41  ? 118.657 88.358  162.129 1.00 86.50  ?  41  PRO S C   1 
ATOM   5011 O O   . PRO D 4 41  ? 118.538 89.084  163.121 1.00 86.50  ?  41  PRO S O   1 
ATOM   5012 C CB  . PRO D 4 41  ? 116.883 87.046  160.926 1.00 86.50  ?  41  PRO S CB  1 
ATOM   5013 C CG  . PRO D 4 41  ? 116.415 86.974  159.497 1.00 86.50  ?  41  PRO S CG  1 
ATOM   5014 C CD  . PRO D 4 41  ? 117.198 87.974  158.675 1.00 86.50  ?  41  PRO S CD  1 
ATOM   5015 N N   . GLU D 4 42  ? 119.694 87.530  161.975 1.00 90.38  ?  42  GLU S N   1 
ATOM   5016 C CA  . GLU D 4 42  ? 120.661 87.375  163.057 1.00 90.38  ?  42  GLU S CA  1 
ATOM   5017 C C   . GLU D 4 42  ? 122.099 87.266  162.555 1.00 90.38  ?  42  GLU S C   1 
ATOM   5018 O O   . GLU D 4 42  ? 122.917 86.578  163.176 1.00 90.38  ?  42  GLU S O   1 
ATOM   5019 C CB  . GLU D 4 42  ? 120.324 86.154  163.916 1.00 90.38  ?  42  GLU S CB  1 
ATOM   5020 N N   . LYS D 4 43  ? 122.438 87.925  161.447 1.00 87.91  ?  43  LYS S N   1 
ATOM   5021 C CA  . LYS D 4 43  ? 123.809 87.864  160.944 1.00 87.91  ?  43  LYS S CA  1 
ATOM   5022 C C   . LYS D 4 43  ? 124.290 89.231  160.465 1.00 87.91  ?  43  LYS S C   1 
ATOM   5023 O O   . LYS D 4 43  ? 124.927 89.350  159.413 1.00 87.91  ?  43  LYS S O   1 
ATOM   5024 C CB  . LYS D 4 43  ? 123.950 86.818  159.838 1.00 87.91  ?  43  LYS S CB  1 
ATOM   5025 C CG  . LYS D 4 43  ? 122.926 86.926  158.734 1.00 87.91  ?  43  LYS S CG  1 
ATOM   5026 C CD  . LYS D 4 43  ? 123.138 85.859  157.675 1.00 87.91  ?  43  LYS S CD  1 
ATOM   5027 C CE  . LYS D 4 43  ? 124.356 86.169  156.821 1.00 87.91  ?  43  LYS S CE  1 
ATOM   5028 N NZ  . LYS D 4 43  ? 124.166 87.413  156.025 1.00 87.91  1  43  LYS S NZ  1 
ATOM   5029 N N   . GLY D 4 44  ? 123.999 90.281  161.231 1.00 78.90  ?  44  GLY S N   1 
ATOM   5030 C CA  . GLY D 4 44  ? 124.638 91.566  161.024 1.00 78.90  ?  44  GLY S CA  1 
ATOM   5031 C C   . GLY D 4 44  ? 124.121 92.343  159.827 1.00 78.90  ?  44  GLY S C   1 
ATOM   5032 O O   . GLY D 4 44  ? 123.222 91.927  159.096 1.00 78.90  ?  44  GLY S O   1 
ATOM   5033 N N   . LEU D 4 45  ? 124.728 93.512  159.632 1.00 69.05  ?  45  LEU S N   1 
ATOM   5034 C CA  . LEU D 4 45  ? 124.338 94.443  158.586 1.00 69.05  ?  45  LEU S CA  1 
ATOM   5035 C C   . LEU D 4 45  ? 124.969 94.066  157.248 1.00 69.05  ?  45  LEU S C   1 
ATOM   5036 O O   . LEU D 4 45  ? 125.903 93.265  157.173 1.00 69.05  ?  45  LEU S O   1 
ATOM   5037 C CB  . LEU D 4 45  ? 124.742 95.870  158.960 1.00 69.05  ?  45  LEU S CB  1 
ATOM   5038 C CG  . LEU D 4 45  ? 124.244 96.430  160.293 1.00 69.05  ?  45  LEU S CG  1 
ATOM   5039 C CD1 . LEU D 4 45  ? 125.000 97.700  160.641 1.00 69.05  ?  45  LEU S CD1 1 
ATOM   5040 C CD2 . LEU D 4 45  ? 122.752 96.704  160.236 1.00 69.05  ?  45  LEU S CD2 1 
ATOM   5041 N N   . GLU D 4 46  ? 124.437 94.662  156.182 1.00 65.70  ?  46  GLU S N   1 
ATOM   5042 C CA  . GLU D 4 46  ? 124.957 94.442  154.834 1.00 65.70  ?  46  GLU S CA  1 
ATOM   5043 C C   . GLU D 4 46  ? 124.485 95.578  153.940 1.00 65.70  ?  46  GLU S C   1 
ATOM   5044 O O   . GLU D 4 46  ? 123.278 95.806  153.816 1.00 65.70  ?  46  GLU S O   1 
ATOM   5045 C CB  . GLU D 4 46  ? 124.499 93.092  154.286 1.00 65.70  ?  46  GLU S CB  1 
ATOM   5046 C CG  . GLU D 4 46  ? 124.509 93.001  152.773 1.00 65.70  ?  46  GLU S CG  1 
ATOM   5047 C CD  . GLU D 4 46  ? 124.539 91.571  152.283 1.00 65.70  ?  46  GLU S CD  1 
ATOM   5048 O OE1 . GLU D 4 46  ? 123.728 90.760  152.776 1.00 65.70  ?  46  GLU S OE1 1 
ATOM   5049 O OE2 . GLU D 4 46  ? 125.362 91.262  151.397 1.00 65.70  -1 46  GLU S OE2 1 
ATOM   5050 N N   . TRP D 4 47  ? 125.429 96.291  153.331 1.00 57.89  ?  47  TRP S N   1 
ATOM   5051 C CA  . TRP D 4 47  ? 125.094 97.411  152.460 1.00 57.89  ?  47  TRP S CA  1 
ATOM   5052 C C   . TRP D 4 47  ? 124.493 96.910  151.151 1.00 57.89  ?  47  TRP S C   1 
ATOM   5053 O O   . TRP D 4 47  ? 124.942 95.906  150.590 1.00 57.89  ?  47  TRP S O   1 
ATOM   5054 C CB  . TRP D 4 47  ? 126.344 98.244  152.185 1.00 57.89  ?  47  TRP S CB  1 
ATOM   5055 C CG  . TRP D 4 47  ? 126.161 99.287  151.142 1.00 57.89  ?  47  TRP S CG  1 
ATOM   5056 C CD1 . TRP D 4 47  ? 125.595 100.513 151.305 1.00 57.89  ?  47  TRP S CD1 1 
ATOM   5057 C CD2 . TRP D 4 47  ? 126.538 99.198  149.764 1.00 57.89  ?  47  TRP S CD2 1 
ATOM   5058 N NE1 . TRP D 4 47  ? 125.600 101.199 150.117 1.00 57.89  ?  47  TRP S NE1 1 
ATOM   5059 C CE2 . TRP D 4 47  ? 126.174 100.412 149.154 1.00 57.89  ?  47  TRP S CE2 1 
ATOM   5060 C CE3 . TRP D 4 47  ? 127.151 98.211  148.986 1.00 57.89  ?  47  TRP S CE3 1 
ATOM   5061 C CZ2 . TRP D 4 47  ? 126.395 100.664 147.804 1.00 57.89  ?  47  TRP S CZ2 1 
ATOM   5062 C CZ3 . TRP D 4 47  ? 127.374 98.467  147.647 1.00 57.89  ?  47  TRP S CZ3 1 
ATOM   5063 C CH2 . TRP D 4 47  ? 126.997 99.682  147.070 1.00 57.89  ?  47  TRP S CH2 1 
ATOM   5064 N N   . VAL D 4 48  ? 123.482 97.625  150.650 1.00 58.41  ?  48  VAL S N   1 
ATOM   5065 C CA  . VAL D 4 48  ? 122.772 97.175  149.456 1.00 58.41  ?  48  VAL S CA  1 
ATOM   5066 C C   . VAL D 4 48  ? 122.930 98.158  148.303 1.00 58.41  ?  48  VAL S C   1 
ATOM   5067 O O   . VAL D 4 48  ? 123.474 97.805  147.252 1.00 58.41  ?  48  VAL S O   1 
ATOM   5068 C CB  . VAL D 4 48  ? 121.281 96.931  149.748 1.00 58.41  ?  48  VAL S CB  1 
ATOM   5069 C CG1 . VAL D 4 48  ? 120.483 96.898  148.454 1.00 58.41  ?  48  VAL S CG1 1 
ATOM   5070 C CG2 . VAL D 4 48  ? 121.110 95.632  150.480 1.00 58.41  ?  48  VAL S CG2 1 
ATOM   5071 N N   . ALA D 4 49  ? 122.459 99.391  148.477 1.00 55.91  ?  49  ALA S N   1 
ATOM   5072 C CA  . ALA D 4 49  ? 122.349 100.289 147.333 1.00 55.91  ?  49  ALA S CA  1 
ATOM   5073 C C   . ALA D 4 49  ? 122.602 101.723 147.768 1.00 55.91  ?  49  ALA S C   1 
ATOM   5074 O O   . ALA D 4 49  ? 122.514 102.057 148.950 1.00 55.91  ?  49  ALA S O   1 
ATOM   5075 C CB  . ALA D 4 49  ? 120.977 100.165 146.662 1.00 55.91  ?  49  ALA S CB  1 
ATOM   5076 N N   . TYR D 4 50  ? 122.909 102.579 146.793 1.00 55.51  ?  50  TYR S N   1 
ATOM   5077 C CA  . TYR D 4 50  ? 123.182 103.981 147.087 1.00 55.51  ?  50  TYR S CA  1 
ATOM   5078 C C   . TYR D 4 50  ? 122.821 104.875 145.910 1.00 55.51  ?  50  TYR S C   1 
ATOM   5079 O O   . TYR D 4 50  ? 123.144 104.561 144.759 1.00 55.51  ?  50  TYR S O   1 
ATOM   5080 C CB  . TYR D 4 50  ? 124.651 104.179 147.458 1.00 55.51  ?  50  TYR S CB  1 
ATOM   5081 C CG  . TYR D 4 50  ? 125.156 105.596 147.323 1.00 55.51  ?  50  TYR S CG  1 
ATOM   5082 C CD1 . TYR D 4 50  ? 124.793 106.577 148.235 1.00 55.51  ?  50  TYR S CD1 1 
ATOM   5083 C CD2 . TYR D 4 50  ? 126.007 105.949 146.288 1.00 55.51  ?  50  TYR S CD2 1 
ATOM   5084 C CE1 . TYR D 4 50  ? 125.264 107.871 148.114 1.00 55.51  ?  50  TYR S CE1 1 
ATOM   5085 C CE2 . TYR D 4 50  ? 126.481 107.233 146.161 1.00 55.51  ?  50  TYR S CE2 1 
ATOM   5086 C CZ  . TYR D 4 50  ? 126.107 108.191 147.074 1.00 55.51  ?  50  TYR S CZ  1 
ATOM   5087 O OH  . TYR D 4 50  ? 126.580 109.473 146.939 1.00 55.51  ?  50  TYR S OH  1 
ATOM   5088 N N   . ILE D 4 51  ? 122.167 105.995 146.220 1.00 57.99  ?  51  ILE S N   1 
ATOM   5089 C CA  . ILE D 4 51  ? 121.835 107.048 145.267 1.00 57.99  ?  51  ILE S CA  1 
ATOM   5090 C C   . ILE D 4 51  ? 122.530 108.328 145.716 1.00 57.99  ?  51  ILE S C   1 
ATOM   5091 O O   . ILE D 4 51  ? 122.487 108.683 146.900 1.00 57.99  ?  51  ILE S O   1 
ATOM   5092 C CB  . ILE D 4 51  ? 120.311 107.249 145.154 1.00 57.99  ?  51  ILE S CB  1 
ATOM   5093 C CG1 . ILE D 4 51  ? 119.961 108.297 144.096 1.00 57.99  ?  51  ILE S CG1 1 
ATOM   5094 C CG2 . ILE D 4 51  ? 119.704 107.619 146.490 1.00 57.99  ?  51  ILE S CG2 1 
ATOM   5095 C CD1 . ILE D 4 51  ? 120.273 107.886 142.696 1.00 57.99  ?  51  ILE S CD1 1 
ATOM   5096 N N   . SER D 4 52  ? 123.197 109.002 144.783 1.00 59.83  ?  52  SER S N   1 
ATOM   5097 C CA  . SER D 4 52  ? 123.926 110.211 145.127 1.00 59.83  ?  52  SER S CA  1 
ATOM   5098 C C   . SER D 4 52  ? 122.990 111.418 145.150 1.00 59.83  ?  52  SER S C   1 
ATOM   5099 O O   . SER D 4 52  ? 121.813 111.340 144.787 1.00 59.83  ?  52  SER S O   1 
ATOM   5100 C CB  . SER D 4 52  ? 125.066 110.449 144.141 1.00 59.83  ?  52  SER S CB  1 
ATOM   5101 N N   . SER D 4 53  ? 123.530 112.551 145.593 1.00 67.24  ?  53  SER S N   1 
ATOM   5102 C CA  . SER D 4 53  ? 122.777 113.796 145.554 1.00 67.24  ?  53  SER S CA  1 
ATOM   5103 C C   . SER D 4 53  ? 122.639 114.262 144.111 1.00 67.24  ?  53  SER S C   1 
ATOM   5104 O O   . SER D 4 53  ? 123.628 114.356 143.379 1.00 67.24  ?  53  SER S O   1 
ATOM   5105 C CB  . SER D 4 53  ? 123.468 114.866 146.399 1.00 67.24  ?  53  SER S CB  1 
ATOM   5106 O OG  . SER D 4 53  ? 124.643 115.338 145.763 1.00 67.24  ?  53  SER S OG  1 
ATOM   5107 N N   . GLY D 4 54  ? 121.407 114.550 143.701 1.00 68.03  ?  54  GLY S N   1 
ATOM   5108 C CA  . GLY D 4 54  ? 121.131 114.863 142.317 1.00 68.03  ?  54  GLY S CA  1 
ATOM   5109 C C   . GLY D 4 54  ? 121.011 113.660 141.409 1.00 68.03  ?  54  GLY S C   1 
ATOM   5110 O O   . GLY D 4 54  ? 120.878 113.837 140.191 1.00 68.03  ?  54  GLY S O   1 
ATOM   5111 N N   . SER D 4 55  ? 121.069 112.447 141.961 1.00 65.76  ?  55  SER S N   1 
ATOM   5112 C CA  . SER D 4 55  ? 120.924 111.196 141.219 1.00 65.76  ?  55  SER S CA  1 
ATOM   5113 C C   . SER D 4 55  ? 121.994 111.022 140.148 1.00 65.76  ?  55  SER S C   1 
ATOM   5114 O O   . SER D 4 55  ? 121.791 110.285 139.179 1.00 65.76  ?  55  SER S O   1 
ATOM   5115 C CB  . SER D 4 55  ? 119.529 111.079 140.595 1.00 65.76  ?  55  SER S CB  1 
ATOM   5116 O OG  . SER D 4 55  ? 118.522 111.386 141.543 1.00 65.76  ?  55  SER S OG  1 
ATOM   5117 N N   . GLY D 4 56  ? 123.140 111.684 140.303 1.00 66.45  ?  56  GLY S N   1 
ATOM   5118 C CA  . GLY D 4 56  ? 124.201 111.578 139.322 1.00 66.45  ?  56  GLY S CA  1 
ATOM   5119 C C   . GLY D 4 56  ? 125.097 110.371 139.465 1.00 66.45  ?  56  GLY S C   1 
ATOM   5120 O O   . GLY D 4 56  ? 125.932 110.131 138.588 1.00 66.45  ?  56  GLY S O   1 
ATOM   5121 N N   . THR D 4 57  ? 124.947 109.606 140.544 1.00 63.62  ?  57  THR S N   1 
ATOM   5122 C CA  . THR D 4 57  ? 125.764 108.421 140.777 1.00 63.62  ?  57  THR S CA  1 
ATOM   5123 C C   . THR D 4 57  ? 124.915 107.375 141.480 1.00 63.62  ?  57  THR S C   1 
ATOM   5124 O O   . THR D 4 57  ? 124.319 107.656 142.523 1.00 63.62  ?  57  THR S O   1 
ATOM   5125 C CB  . THR D 4 57  ? 127.001 108.754 141.612 1.00 63.62  ?  57  THR S CB  1 
ATOM   5126 O OG1 . THR D 4 57  ? 127.738 109.806 140.980 1.00 63.62  ?  57  THR S OG1 1 
ATOM   5127 C CG2 . THR D 4 57  ? 127.887 107.538 141.733 1.00 63.62  ?  57  THR S CG2 1 
ATOM   5128 N N   . ILE D 4 58  ? 124.867 106.174 140.913 1.00 62.77  ?  58  ILE S N   1 
ATOM   5129 C CA  . ILE D 4 58  ? 124.049 105.082 141.426 1.00 62.77  ?  58  ILE S CA  1 
ATOM   5130 C C   . ILE D 4 58  ? 124.959 103.878 141.615 1.00 62.77  ?  58  ILE S C   1 
ATOM   5131 O O   . ILE D 4 58  ? 125.758 103.556 140.727 1.00 62.77  ?  58  ILE S O   1 
ATOM   5132 C CB  . ILE D 4 58  ? 122.892 104.745 140.475 1.00 62.77  ?  58  ILE S CB  1 
ATOM   5133 C CG1 . ILE D 4 58  ? 121.948 105.934 140.338 1.00 62.77  ?  58  ILE S CG1 1 
ATOM   5134 C CG2 . ILE D 4 58  ? 122.112 103.563 140.993 1.00 62.77  ?  58  ILE S CG2 1 
ATOM   5135 C CD1 . ILE D 4 58  ? 120.935 105.774 139.231 1.00 62.77  ?  58  ILE S CD1 1 
ATOM   5136 N N   . TYR D 4 59  ? 124.850 103.220 142.766 1.00 64.06  ?  59  TYR S N   1 
ATOM   5137 C CA  . TYR D 4 59  ? 125.668 102.053 143.057 1.00 64.06  ?  59  TYR S CA  1 
ATOM   5138 C C   . TYR D 4 59  ? 124.832 100.950 143.688 1.00 64.06  ?  59  TYR S C   1 
ATOM   5139 O O   . TYR D 4 59  ? 123.870 101.216 144.413 1.00 64.06  ?  59  TYR S O   1 
ATOM   5140 C CB  . TYR D 4 59  ? 126.830 102.401 143.982 1.00 64.06  ?  59  TYR S CB  1 
ATOM   5141 C CG  . TYR D 4 59  ? 127.953 103.170 143.326 1.00 64.06  ?  59  TYR S CG  1 
ATOM   5142 C CD1 . TYR D 4 59  ? 128.508 102.738 142.132 1.00 64.06  ?  59  TYR S CD1 1 
ATOM   5143 C CD2 . TYR D 4 59  ? 128.478 104.310 143.917 1.00 64.06  ?  59  TYR S CD2 1 
ATOM   5144 C CE1 . TYR D 4 59  ? 129.542 103.427 141.536 1.00 64.06  ?  59  TYR S CE1 1 
ATOM   5145 C CE2 . TYR D 4 59  ? 129.515 105.003 143.333 1.00 64.06  ?  59  TYR S CE2 1 
ATOM   5146 C CZ  . TYR D 4 59  ? 130.041 104.561 142.140 1.00 64.06  ?  59  TYR S CZ  1 
ATOM   5147 O OH  . TYR D 4 59  ? 131.074 105.251 141.552 1.00 64.06  ?  59  TYR S OH  1 
ATOM   5148 N N   . TYR D 4 60  ? 125.225 99.705  143.420 1.00 66.97  ?  60  TYR S N   1 
ATOM   5149 C CA  . TYR D 4 60  ? 124.538 98.534  143.944 1.00 66.97  ?  60  TYR S CA  1 
ATOM   5150 C C   . TYR D 4 60  ? 125.558 97.543  144.485 1.00 66.97  ?  60  TYR S C   1 
ATOM   5151 O O   . TYR D 4 60  ? 126.729 97.549  144.098 1.00 66.97  ?  60  TYR S O   1 
ATOM   5152 C CB  . TYR D 4 60  ? 123.688 97.848  142.870 1.00 66.97  ?  60  TYR S CB  1 
ATOM   5153 C CG  . TYR D 4 60  ? 122.621 98.736  142.286 1.00 66.97  ?  60  TYR S CG  1 
ATOM   5154 C CD1 . TYR D 4 60  ? 121.405 98.916  142.926 1.00 66.97  ?  60  TYR S CD1 1 
ATOM   5155 C CD2 . TYR D 4 60  ? 122.833 99.389  141.082 1.00 66.97  ?  60  TYR S CD2 1 
ATOM   5156 C CE1 . TYR D 4 60  ? 120.435 99.733  142.386 1.00 66.97  ?  60  TYR S CE1 1 
ATOM   5157 C CE2 . TYR D 4 60  ? 121.871 100.198 140.534 1.00 66.97  ?  60  TYR S CE2 1 
ATOM   5158 C CZ  . TYR D 4 60  ? 120.675 100.371 141.187 1.00 66.97  ?  60  TYR S CZ  1 
ATOM   5159 O OH  . TYR D 4 60  ? 119.718 101.187 140.632 1.00 66.97  ?  60  TYR S OH  1 
ATOM   5160 N N   . ALA D 4 61  ? 125.097 96.682  145.387 1.00 71.73  ?  61  ALA S N   1 
ATOM   5161 C CA  . ALA D 4 61  ? 125.935 95.607  145.888 1.00 71.73  ?  61  ALA S CA  1 
ATOM   5162 C C   . ALA D 4 61  ? 126.090 94.518  144.828 1.00 71.73  ?  61  ALA S C   1 
ATOM   5163 O O   . ALA D 4 61  ? 125.369 94.476  143.828 1.00 71.73  ?  61  ALA S O   1 
ATOM   5164 C CB  . ALA D 4 61  ? 125.354 95.024  147.174 1.00 71.73  ?  61  ALA S CB  1 
ATOM   5165 N N   . ASP D 4 62  ? 127.056 93.627  145.056 1.00 81.79  ?  62  ASP S N   1 
ATOM   5166 C CA  . ASP D 4 62  ? 127.305 92.553  144.100 1.00 81.79  ?  62  ASP S CA  1 
ATOM   5167 C C   . ASP D 4 62  ? 126.165 91.543  144.071 1.00 81.79  ?  62  ASP S C   1 
ATOM   5168 O O   . ASP D 4 62  ? 125.898 90.945  143.023 1.00 81.79  ?  62  ASP S O   1 
ATOM   5169 C CB  . ASP D 4 62  ? 128.624 91.853  144.425 1.00 81.79  ?  62  ASP S CB  1 
ATOM   5170 C CG  . ASP D 4 62  ? 128.669 91.324  145.845 1.00 81.79  ?  62  ASP S CG  1 
ATOM   5171 O OD1 . ASP D 4 62  ? 128.585 92.139  146.787 1.00 81.79  ?  62  ASP S OD1 1 
ATOM   5172 O OD2 . ASP D 4 62  ? 128.786 90.092  146.019 1.00 81.79  -1 62  ASP S OD2 1 
ATOM   5173 N N   . THR D 4 63  ? 125.484 91.341  145.196 1.00 79.35  ?  63  THR S N   1 
ATOM   5174 C CA  . THR D 4 63  ? 124.413 90.358  145.290 1.00 79.35  ?  63  THR S CA  1 
ATOM   5175 C C   . THR D 4 63  ? 123.064 90.893  144.829 1.00 79.35  ?  63  THR S C   1 
ATOM   5176 O O   . THR D 4 63  ? 122.103 90.121  144.752 1.00 79.35  ?  63  THR S O   1 
ATOM   5177 C CB  . THR D 4 63  ? 124.290 89.846  146.728 1.00 79.35  ?  63  THR S CB  1 
ATOM   5178 O OG1 . THR D 4 63  ? 124.058 90.950  147.612 1.00 79.35  ?  63  THR S OG1 1 
ATOM   5179 C CG2 . THR D 4 63  ? 125.561 89.126  147.148 1.00 79.35  ?  63  THR S CG2 1 
ATOM   5180 N N   . VAL D 4 64  ? 122.961 92.188  144.524 1.00 76.54  ?  64  VAL S N   1 
ATOM   5181 C CA  . VAL D 4 64  ? 121.708 92.786  144.083 1.00 76.54  ?  64  VAL S CA  1 
ATOM   5182 C C   . VAL D 4 64  ? 121.860 93.613  142.817 1.00 76.54  ?  64  VAL S C   1 
ATOM   5183 O O   . VAL D 4 64  ? 120.901 94.261  142.399 1.00 76.54  ?  64  VAL S O   1 
ATOM   5184 C CB  . VAL D 4 64  ? 121.069 93.642  145.197 1.00 76.54  ?  64  VAL S CB  1 
ATOM   5185 C CG1 . VAL D 4 64  ? 120.651 92.770  146.370 1.00 76.54  ?  64  VAL S CG1 1 
ATOM   5186 C CG2 . VAL D 4 64  ? 122.029 94.730  145.643 1.00 76.54  ?  64  VAL S CG2 1 
ATOM   5187 N N   . LYS D 4 65  ? 123.036 93.621  142.194 1.00 78.85  ?  65  LYS S N   1 
ATOM   5188 C CA  . LYS D 4 65  ? 123.238 94.409  140.986 1.00 78.85  ?  65  LYS S CA  1 
ATOM   5189 C C   . LYS D 4 65  ? 122.374 93.869  139.853 1.00 78.85  ?  65  LYS S C   1 
ATOM   5190 O O   . LYS D 4 65  ? 122.340 92.660  139.605 1.00 78.85  ?  65  LYS S O   1 
ATOM   5191 C CB  . LYS D 4 65  ? 124.711 94.395  140.583 1.00 78.85  ?  65  LYS S CB  1 
ATOM   5192 C CG  . LYS D 4 65  ? 125.043 95.306  139.414 1.00 78.85  ?  65  LYS S CG  1 
ATOM   5193 C CD  . LYS D 4 65  ? 126.523 95.246  139.074 1.00 78.85  ?  65  LYS S CD  1 
ATOM   5194 C CE  . LYS D 4 65  ? 127.365 95.927  140.141 1.00 78.85  ?  65  LYS S CE  1 
ATOM   5195 N NZ  . LYS D 4 65  ? 127.127 97.396  140.184 1.00 78.85  1  65  LYS S NZ  1 
ATOM   5196 N N   . GLY D 4 66  ? 121.673 94.769  139.168 1.00 79.66  ?  66  GLY S N   1 
ATOM   5197 C CA  . GLY D 4 66  ? 120.785 94.378  138.091 1.00 79.66  ?  66  GLY S CA  1 
ATOM   5198 C C   . GLY D 4 66  ? 119.429 93.918  138.585 1.00 79.66  ?  66  GLY S C   1 
ATOM   5199 O O   . GLY D 4 66  ? 118.398 94.227  137.979 1.00 79.66  ?  66  GLY S O   1 
ATOM   5200 N N   . ARG D 4 67  ? 119.420 93.173  139.691 1.00 80.09  ?  67  ARG S N   1 
ATOM   5201 C CA  . ARG D 4 67  ? 118.164 92.692  140.254 1.00 80.09  ?  67  ARG S CA  1 
ATOM   5202 C C   . ARG D 4 67  ? 117.399 93.818  140.941 1.00 80.09  ?  67  ARG S C   1 
ATOM   5203 O O   . ARG D 4 67  ? 116.166 93.872  140.869 1.00 80.09  ?  67  ARG S O   1 
ATOM   5204 C CB  . ARG D 4 67  ? 118.440 91.550  141.231 1.00 80.09  ?  67  ARG S CB  1 
ATOM   5205 C CG  . ARG D 4 67  ? 117.329 90.525  141.322 1.00 80.09  ?  67  ARG S CG  1 
ATOM   5206 C CD  . ARG D 4 67  ? 117.838 89.216  141.899 1.00 80.09  ?  67  ARG S CD  1 
ATOM   5207 N NE  . ARG D 4 67  ? 118.778 89.428  142.993 1.00 80.09  ?  67  ARG S NE  1 
ATOM   5208 C CZ  . ARG D 4 67  ? 118.436 89.498  144.271 1.00 80.09  ?  67  ARG S CZ  1 
ATOM   5209 N NH1 . ARG D 4 67  ? 117.177 89.375  144.658 1.00 80.09  1  67  ARG S NH1 1 
ATOM   5210 N NH2 . ARG D 4 67  ? 119.381 89.695  145.186 1.00 80.09  ?  67  ARG S NH2 1 
ATOM   5211 N N   . PHE D 4 68  ? 118.110 94.720  141.608 1.00 76.52  ?  68  PHE S N   1 
ATOM   5212 C CA  . PHE D 4 68  ? 117.510 95.832  142.330 1.00 76.52  ?  68  PHE S CA  1 
ATOM   5213 C C   . PHE D 4 68  ? 117.677 97.124  141.539 1.00 76.52  ?  68  PHE S C   1 
ATOM   5214 O O   . PHE D 4 68  ? 118.466 97.210  140.596 1.00 76.52  ?  68  PHE S O   1 
ATOM   5215 C CB  . PHE D 4 68  ? 118.147 95.985  143.716 1.00 76.52  ?  68  PHE S CB  1 
ATOM   5216 C CG  . PHE D 4 68  ? 117.677 94.976  144.728 1.00 76.52  ?  68  PHE S CG  1 
ATOM   5217 C CD1 . PHE D 4 68  ? 117.150 93.759  144.333 1.00 76.52  ?  68  PHE S CD1 1 
ATOM   5218 C CD2 . PHE D 4 68  ? 117.781 95.244  146.081 1.00 76.52  ?  68  PHE S CD2 1 
ATOM   5219 C CE1 . PHE D 4 68  ? 116.729 92.835  145.266 1.00 76.52  ?  68  PHE S CE1 1 
ATOM   5220 C CE2 . PHE D 4 68  ? 117.361 94.323  147.018 1.00 76.52  ?  68  PHE S CE2 1 
ATOM   5221 C CZ  . PHE D 4 68  ? 116.837 93.117  146.609 1.00 76.52  ?  68  PHE S CZ  1 
ATOM   5222 N N   . THR D 4 69  ? 116.918 98.143  141.937 1.00 72.96  ?  69  THR S N   1 
ATOM   5223 C CA  . THR D 4 69  ? 117.126 99.484  141.413 1.00 72.96  ?  69  THR S CA  1 
ATOM   5224 C C   . THR D 4 69  ? 116.714 100.496 142.472 1.00 72.96  ?  69  THR S C   1 
ATOM   5225 O O   . THR D 4 69  ? 115.786 100.253 143.247 1.00 72.96  ?  69  THR S O   1 
ATOM   5226 C CB  . THR D 4 69  ? 116.356 99.718  140.106 1.00 72.96  ?  69  THR S CB  1 
ATOM   5227 O OG1 . THR D 4 69  ? 116.510 101.082 139.694 1.00 72.96  ?  69  THR S OG1 1 
ATOM   5228 C CG2 . THR D 4 69  ? 114.887 99.406  140.280 1.00 72.96  ?  69  THR S CG2 1 
ATOM   5229 N N   . ILE D 4 70  ? 117.423 101.621 142.511 1.00 66.96  ?  70  ILE S N   1 
ATOM   5230 C CA  . ILE D 4 70  ? 117.213 102.657 143.513 1.00 66.96  ?  70  ILE S CA  1 
ATOM   5231 C C   . ILE D 4 70  ? 116.978 103.984 142.804 1.00 66.96  ?  70  ILE S C   1 
ATOM   5232 O O   . ILE D 4 70  ? 117.603 104.272 141.778 1.00 66.96  ?  70  ILE S O   1 
ATOM   5233 C CB  . ILE D 4 70  ? 118.405 102.750 144.492 1.00 66.96  ?  70  ILE S CB  1 
ATOM   5234 C CG1 . ILE D 4 70  ? 118.111 103.748 145.614 1.00 66.96  ?  70  ILE S CG1 1 
ATOM   5235 C CG2 . ILE D 4 70  ? 119.688 103.115 143.762 1.00 66.96  ?  70  ILE S CG2 1 
ATOM   5236 C CD1 . ILE D 4 70  ? 119.208 103.841 146.647 1.00 66.96  ?  70  ILE S CD1 1 
ATOM   5237 N N   . SER D 4 71  ? 116.056 104.779 143.341 1.00 68.67  ?  71  SER S N   1 
ATOM   5238 C CA  . SER D 4 71  ? 115.732 106.076 142.768 1.00 68.67  ?  71  SER S CA  1 
ATOM   5239 C C   . SER D 4 71  ? 115.288 107.006 143.887 1.00 68.67  ?  71  SER S C   1 
ATOM   5240 O O   . SER D 4 71  ? 115.070 106.583 145.024 1.00 68.67  ?  71  SER S O   1 
ATOM   5241 C CB  . SER D 4 71  ? 114.649 105.958 141.691 1.00 68.67  ?  71  SER S CB  1 
ATOM   5242 O OG  . SER D 4 71  ? 113.511 105.275 142.187 1.00 68.67  ?  71  SER S OG  1 
ATOM   5243 N N   . ARG D 4 72  ? 115.157 108.287 143.557 1.00 66.07  ?  72  ARG S N   1 
ATOM   5244 C CA  . ARG D 4 72  ? 114.712 109.270 144.532 1.00 66.07  ?  72  ARG S CA  1 
ATOM   5245 C C   . ARG D 4 72  ? 113.804 110.290 143.862 1.00 66.07  ?  72  ARG S C   1 
ATOM   5246 O O   . ARG D 4 72  ? 113.981 110.634 142.690 1.00 66.07  ?  72  ARG S O   1 
ATOM   5247 C CB  . ARG D 4 72  ? 115.898 109.975 145.206 1.00 66.07  ?  72  ARG S CB  1 
ATOM   5248 C CG  . ARG D 4 72  ? 116.670 110.914 144.299 1.00 66.07  ?  72  ARG S CG  1 
ATOM   5249 C CD  . ARG D 4 72  ? 118.016 111.265 144.898 1.00 66.07  ?  72  ARG S CD  1 
ATOM   5250 N NE  . ARG D 4 72  ? 117.891 111.762 146.263 1.00 66.07  ?  72  ARG S NE  1 
ATOM   5251 C CZ  . ARG D 4 72  ? 118.917 112.055 147.048 1.00 66.07  ?  72  ARG S CZ  1 
ATOM   5252 N NH1 . ARG D 4 72  ? 120.165 111.913 146.636 1.00 66.07  1  72  ARG S NH1 1 
ATOM   5253 N NH2 . ARG D 4 72  ? 118.685 112.502 148.279 1.00 66.07  ?  72  ARG S NH2 1 
ATOM   5254 N N   . ASP D 4 73  ? 112.818 110.757 144.622 1.00 74.52  ?  73  ASP S N   1 
ATOM   5255 C CA  . ASP D 4 73  ? 111.933 111.847 144.227 1.00 74.52  ?  73  ASP S CA  1 
ATOM   5256 C C   . ASP D 4 73  ? 112.214 113.001 145.182 1.00 74.52  ?  73  ASP S C   1 
ATOM   5257 O O   . ASP D 4 73  ? 111.681 113.040 146.297 1.00 74.52  ?  73  ASP S O   1 
ATOM   5258 C CB  . ASP D 4 73  ? 110.469 111.418 144.270 1.00 74.52  ?  73  ASP S CB  1 
ATOM   5259 N N   . ASP D 4 74  ? 113.083 113.915 144.752 1.00 77.09  ?  74  ASP S N   1 
ATOM   5260 C CA  . ASP D 4 74  ? 113.432 115.066 145.583 1.00 77.09  ?  74  ASP S CA  1 
ATOM   5261 C C   . ASP D 4 74  ? 112.247 115.979 145.870 1.00 77.09  ?  74  ASP S C   1 
ATOM   5262 O O   . ASP D 4 74  ? 112.094 116.400 147.030 1.00 77.09  ?  74  ASP S O   1 
ATOM   5263 C CB  . ASP D 4 74  ? 114.589 115.834 144.934 1.00 77.09  ?  74  ASP S CB  1 
ATOM   5264 C CG  . ASP D 4 74  ? 115.886 115.052 144.951 1.00 77.09  ?  74  ASP S CG  1 
ATOM   5265 O OD1 . ASP D 4 74  ? 116.034 114.165 145.816 1.00 77.09  ?  74  ASP S OD1 1 
ATOM   5266 O OD2 . ASP D 4 74  ? 116.757 115.325 144.099 1.00 77.09  -1 74  ASP S OD2 1 
ATOM   5267 N N   . PRO D 4 75  ? 111.396 116.347 144.899 1.00 80.36  ?  75  PRO S N   1 
ATOM   5268 C CA  . PRO D 4 75  ? 110.248 117.203 145.247 1.00 80.36  ?  75  PRO S CA  1 
ATOM   5269 C C   . PRO D 4 75  ? 109.334 116.596 146.295 1.00 80.36  ?  75  PRO S C   1 
ATOM   5270 O O   . PRO D 4 75  ? 108.777 117.328 147.123 1.00 80.36  ?  75  PRO S O   1 
ATOM   5271 C CB  . PRO D 4 75  ? 109.533 117.384 143.902 1.00 80.36  ?  75  PRO S CB  1 
ATOM   5272 C CG  . PRO D 4 75  ? 110.604 117.232 142.894 1.00 80.36  ?  75  PRO S CG  1 
ATOM   5273 C CD  . PRO D 4 75  ? 111.503 116.164 143.439 1.00 80.36  ?  75  PRO S CD  1 
ATOM   5274 N N   . LYS D 4 76  ? 109.160 115.276 146.286 1.00 78.97  ?  76  LYS S N   1 
ATOM   5275 C CA  . LYS D 4 76  ? 108.346 114.593 147.281 1.00 78.97  ?  76  LYS S CA  1 
ATOM   5276 C C   . LYS D 4 76  ? 109.162 114.103 148.470 1.00 78.97  ?  76  LYS S C   1 
ATOM   5277 O O   . LYS D 4 76  ? 108.589 113.537 149.407 1.00 78.97  ?  76  LYS S O   1 
ATOM   5278 C CB  . LYS D 4 76  ? 107.598 113.423 146.639 1.00 78.97  ?  76  LYS S CB  1 
ATOM   5279 C CG  . LYS D 4 76  ? 106.594 113.842 145.578 1.00 78.97  ?  76  LYS S CG  1 
ATOM   5280 C CD  . LYS D 4 76  ? 105.837 112.644 145.029 1.00 78.97  ?  76  LYS S CD  1 
ATOM   5281 C CE  . LYS D 4 76  ? 106.736 111.767 144.176 1.00 78.97  ?  76  LYS S CE  1 
ATOM   5282 N NZ  . LYS D 4 76  ? 107.177 112.466 142.938 1.00 78.97  1  76  LYS S NZ  1 
ATOM   5283 N N   . ASN D 4 77  ? 110.482 114.312 148.453 1.00 74.80  ?  77  ASN S N   1 
ATOM   5284 C CA  . ASN D 4 77  ? 111.366 113.920 149.552 1.00 74.80  ?  77  ASN S CA  1 
ATOM   5285 C C   . ASN D 4 77  ? 111.230 112.432 149.871 1.00 74.80  ?  77  ASN S C   1 
ATOM   5286 O O   . ASN D 4 77  ? 111.028 112.037 151.020 1.00 74.80  ?  77  ASN S O   1 
ATOM   5287 C CB  . ASN D 4 77  ? 111.101 114.769 150.799 1.00 74.80  ?  77  ASN S CB  1 
ATOM   5288 C CG  . ASN D 4 77  ? 111.903 116.053 150.816 1.00 74.80  ?  77  ASN S CG  1 
ATOM   5289 O OD1 . ASN D 4 77  ? 112.380 116.516 149.781 1.00 74.80  ?  77  ASN S OD1 1 
ATOM   5290 N ND2 . ASN D 4 77  ? 112.055 116.639 151.997 1.00 74.80  ?  77  ASN S ND2 1 
ATOM   5291 N N   . THR D 4 78  ? 111.342 111.598 148.839 1.00 72.33  ?  78  THR S N   1 
ATOM   5292 C CA  . THR D 4 78  ? 111.126 110.169 149.001 1.00 72.33  ?  78  THR S CA  1 
ATOM   5293 C C   . THR D 4 78  ? 112.251 109.388 148.335 1.00 72.33  ?  78  THR S C   1 
ATOM   5294 O O   . THR D 4 78  ? 112.817 109.817 147.329 1.00 72.33  ?  78  THR S O   1 
ATOM   5295 C CB  . THR D 4 78  ? 109.766 109.746 148.419 1.00 72.33  ?  78  THR S CB  1 
ATOM   5296 O OG1 . THR D 4 78  ? 108.739 110.582 148.963 1.00 72.33  ?  78  THR S OG1 1 
ATOM   5297 C CG2 . THR D 4 78  ? 109.449 108.310 148.790 1.00 72.33  ?  78  THR S CG2 1 
ATOM   5298 N N   . LEU D 4 79  ? 112.579 108.239 148.920 1.00 69.12  ?  79  LEU S N   1 
ATOM   5299 C CA  . LEU D 4 79  ? 113.581 107.325 148.390 1.00 69.12  ?  79  LEU S CA  1 
ATOM   5300 C C   . LEU D 4 79  ? 112.913 105.998 148.060 1.00 69.12  ?  79  LEU S C   1 
ATOM   5301 O O   . LEU D 4 79  ? 112.240 105.413 148.912 1.00 69.12  ?  79  LEU S O   1 
ATOM   5302 C CB  . LEU D 4 79  ? 114.713 107.118 149.398 1.00 69.12  ?  79  LEU S CB  1 
ATOM   5303 C CG  . LEU D 4 79  ? 115.801 106.123 149.007 1.00 69.12  ?  79  LEU S CG  1 
ATOM   5304 C CD1 . LEU D 4 79  ? 116.617 106.678 147.869 1.00 69.12  ?  79  LEU S CD1 1 
ATOM   5305 C CD2 . LEU D 4 79  ? 116.688 105.817 150.198 1.00 69.12  ?  79  LEU S CD2 1 
ATOM   5306 N N   . PHE D 4 80  ? 113.097 105.525 146.830 1.00 71.14  ?  80  PHE S N   1 
ATOM   5307 C CA  . PHE D 4 80  ? 112.451 104.316 146.344 1.00 71.14  ?  80  PHE S CA  1 
ATOM   5308 C C   . PHE D 4 80  ? 113.488 103.241 146.065 1.00 71.14  ?  80  PHE S C   1 
ATOM   5309 O O   . PHE D 4 80  ? 114.549 103.518 145.495 1.00 71.14  ?  80  PHE S O   1 
ATOM   5310 C CB  . PHE D 4 80  ? 111.654 104.586 145.066 1.00 71.14  ?  80  PHE S CB  1 
ATOM   5311 C CG  . PHE D 4 80  ? 110.533 105.565 145.240 1.00 71.14  ?  80  PHE S CG  1 
ATOM   5312 C CD1 . PHE D 4 80  ? 109.480 105.288 146.092 1.00 71.14  ?  80  PHE S CD1 1 
ATOM   5313 C CD2 . PHE D 4 80  ? 110.527 106.760 144.541 1.00 71.14  ?  80  PHE S CD2 1 
ATOM   5314 C CE1 . PHE D 4 80  ? 108.443 106.182 146.245 1.00 71.14  ?  80  PHE S CE1 1 
ATOM   5315 C CE2 . PHE D 4 80  ? 109.495 107.661 144.693 1.00 71.14  ?  80  PHE S CE2 1 
ATOM   5316 C CZ  . PHE D 4 80  ? 108.451 107.372 145.546 1.00 71.14  ?  80  PHE S CZ  1 
ATOM   5317 N N   . LEU D 4 81  ? 113.168 102.012 146.459 1.00 70.41  ?  81  LEU S N   1 
ATOM   5318 C CA  . LEU D 4 81  ? 113.962 100.834 146.126 1.00 70.41  ?  81  LEU S CA  1 
ATOM   5319 C C   . LEU D 4 81  ? 113.029 99.803  145.507 1.00 70.41  ?  81  LEU S C   1 
ATOM   5320 O O   . LEU D 4 81  ? 112.217 99.195  146.211 1.00 70.41  ?  81  LEU S O   1 
ATOM   5321 C CB  . LEU D 4 81  ? 114.663 100.267 147.359 1.00 70.41  ?  81  LEU S CB  1 
ATOM   5322 C CG  . LEU D 4 81  ? 115.544 99.040  147.117 1.00 70.41  ?  81  LEU S CG  1 
ATOM   5323 C CD1 . LEU D 4 81  ? 116.902 99.451  146.577 1.00 70.41  ?  81  LEU S CD1 1 
ATOM   5324 C CD2 . LEU D 4 81  ? 115.697 98.223  148.388 1.00 70.41  ?  81  LEU S CD2 1 
ATOM   5325 N N   . GLN D 4 82  ? 113.123 99.629  144.192 1.00 79.79  ?  82  GLN S N   1 
ATOM   5326 C CA  . GLN D 4 82  ? 112.347 98.615  143.492 1.00 79.79  ?  82  GLN S CA  1 
ATOM   5327 C C   . GLN D 4 82  ? 113.186 97.346  143.402 1.00 79.79  ?  82  GLN S C   1 
ATOM   5328 O O   . GLN D 4 82  ? 114.232 97.330  142.742 1.00 79.79  ?  82  GLN S O   1 
ATOM   5329 C CB  . GLN D 4 82  ? 111.935 99.107  142.106 1.00 79.79  ?  82  GLN S CB  1 
ATOM   5330 C CG  . GLN D 4 82  ? 111.077 98.131  141.319 1.00 79.79  ?  82  GLN S CG  1 
ATOM   5331 C CD  . GLN D 4 82  ? 109.732 97.883  141.968 1.00 79.79  ?  82  GLN S CD  1 
ATOM   5332 O OE1 . GLN D 4 82  ? 108.817 98.699  141.859 1.00 79.79  ?  82  GLN S OE1 1 
ATOM   5333 N NE2 . GLN D 4 82  ? 109.603 96.749  142.645 1.00 79.79  ?  82  GLN S NE2 1 
ATOM   5334 N N   . MET D 4 83  ? 112.730 96.291  144.071 1.00 83.54  ?  83  MET S N   1 
ATOM   5335 C CA  . MET D 4 83  ? 113.500 95.068  144.247 1.00 83.54  ?  83  MET S CA  1 
ATOM   5336 C C   . MET D 4 83  ? 112.698 93.902  143.688 1.00 83.54  ?  83  MET S C   1 
ATOM   5337 O O   . MET D 4 83  ? 111.595 93.612  144.163 1.00 83.54  ?  83  MET S O   1 
ATOM   5338 C CB  . MET D 4 83  ? 113.872 94.897  145.730 1.00 83.54  ?  83  MET S CB  1 
ATOM   5339 C CG  . MET D 4 83  ? 112.707 94.697  146.695 1.00 83.54  ?  83  MET S CG  1 
ATOM   5340 S SD  . MET D 4 83  ? 113.195 94.502  148.424 1.00 83.54  ?  83  MET S SD  1 
ATOM   5341 C CE  . MET D 4 83  ? 113.919 92.870  148.442 1.00 83.54  ?  83  MET S CE  1 
ATOM   5342 N N   . THR D 4 84  ? 113.235 93.264  142.651 1.00 85.64  ?  84  THR S N   1 
ATOM   5343 C CA  . THR D 4 84  ? 112.534 92.247  141.882 1.00 85.64  ?  84  THR S CA  1 
ATOM   5344 C C   . THR D 4 84  ? 113.286 90.925  141.954 1.00 85.64  ?  84  THR S C   1 
ATOM   5345 O O   . THR D 4 84  ? 114.411 90.850  142.453 1.00 85.64  ?  84  THR S O   1 
ATOM   5346 C CB  . THR D 4 84  ? 112.375 92.673  140.416 1.00 85.64  ?  84  THR S CB  1 
ATOM   5347 O OG1 . THR D 4 84  ? 113.654 92.652  139.772 1.00 85.64  ?  84  THR S OG1 1 
ATOM   5348 C CG2 . THR D 4 84  ? 111.803 94.078  140.326 1.00 85.64  ?  84  THR S CG2 1 
ATOM   5349 N N   . SER D 4 85  ? 112.642 89.877  141.437 1.00 87.15  ?  85  SER S N   1 
ATOM   5350 C CA  . SER D 4 85  ? 113.219 88.533  141.380 1.00 87.15  ?  85  SER S CA  1 
ATOM   5351 C C   . SER D 4 85  ? 113.712 88.093  142.756 1.00 87.15  ?  85  SER S C   1 
ATOM   5352 O O   . SER D 4 85  ? 114.811 87.557  142.913 1.00 87.15  ?  85  SER S O   1 
ATOM   5353 C CB  . SER D 4 85  ? 114.341 88.463  140.344 1.00 87.15  ?  85  SER S CB  1 
ATOM   5354 O OG  . SER D 4 85  ? 115.102 87.278  140.497 1.00 87.15  ?  85  SER S OG  1 
ATOM   5355 N N   . LEU D 4 86  ? 112.881 88.336  143.764 1.00 86.47  ?  86  LEU S N   1 
ATOM   5356 C CA  . LEU D 4 86  ? 113.289 88.123  145.145 1.00 86.47  ?  86  LEU S CA  1 
ATOM   5357 C C   . LEU D 4 86  ? 113.475 86.641  145.439 1.00 86.47  ?  86  LEU S C   1 
ATOM   5358 O O   . LEU D 4 86  ? 112.687 85.798  145.003 1.00 86.47  ?  86  LEU S O   1 
ATOM   5359 C CB  . LEU D 4 86  ? 112.258 88.723  146.098 1.00 86.47  ?  86  LEU S CB  1 
ATOM   5360 C CG  . LEU D 4 86  ? 111.948 90.205  145.883 1.00 86.47  ?  86  LEU S CG  1 
ATOM   5361 C CD1 . LEU D 4 86  ? 111.247 90.790  147.095 1.00 86.47  ?  86  LEU S CD1 1 
ATOM   5362 C CD2 . LEU D 4 86  ? 113.210 90.987  145.558 1.00 86.47  ?  86  LEU S CD2 1 
ATOM   5363 N N   . ARG D 4 87  ? 114.525 86.330  146.187 1.00 88.68  ?  87  ARG S N   1 
ATOM   5364 C CA  . ARG D 4 87  ? 114.844 84.975  146.606 1.00 88.68  ?  87  ARG S CA  1 
ATOM   5365 C C   . ARG D 4 87  ? 114.853 84.906  148.130 1.00 88.68  ?  87  ARG S C   1 
ATOM   5366 O O   . ARG D 4 87  ? 114.662 85.909  148.821 1.00 88.68  ?  87  ARG S O   1 
ATOM   5367 C CB  . ARG D 4 87  ? 116.187 84.529  146.020 1.00 88.68  ?  87  ARG S CB  1 
ATOM   5368 C CG  . ARG D 4 87  ? 117.383 85.281  146.571 1.00 88.68  ?  87  ARG S CG  1 
ATOM   5369 C CD  . ARG D 4 87  ? 118.662 84.863  145.867 1.00 88.68  ?  87  ARG S CD  1 
ATOM   5370 N NE  . ARG D 4 87  ? 118.680 85.299  144.476 1.00 88.68  ?  87  ARG S NE  1 
ATOM   5371 C CZ  . ARG D 4 87  ? 119.604 84.947  143.593 1.00 88.68  ?  87  ARG S CZ  1 
ATOM   5372 N NH1 . ARG D 4 87  ? 120.604 84.146  143.921 1.00 88.68  1  87  ARG S NH1 1 
ATOM   5373 N NH2 . ARG D 4 87  ? 119.521 85.408  142.348 1.00 88.68  ?  87  ARG S NH2 1 
ATOM   5374 N N   . SER D 4 88  ? 115.082 83.700  148.654 1.00 88.97  ?  88  SER S N   1 
ATOM   5375 C CA  . SER D 4 88  ? 115.047 83.494  150.098 1.00 88.97  ?  88  SER S CA  1 
ATOM   5376 C C   . SER D 4 88  ? 116.149 84.252  150.824 1.00 88.97  ?  88  SER S C   1 
ATOM   5377 O O   . SER D 4 88  ? 116.034 84.481  152.033 1.00 88.97  ?  88  SER S O   1 
ATOM   5378 C CB  . SER D 4 88  ? 115.148 82.002  150.418 1.00 88.97  ?  88  SER S CB  1 
ATOM   5379 O OG  . SER D 4 88  ? 115.329 81.792  151.808 1.00 88.97  ?  88  SER S OG  1 
ATOM   5380 N N   . GLU D 4 89  ? 117.211 84.646  150.123 1.00 86.39  ?  89  GLU S N   1 
ATOM   5381 C CA  . GLU D 4 89  ? 118.316 85.355  150.754 1.00 86.39  ?  89  GLU S CA  1 
ATOM   5382 C C   . GLU D 4 89  ? 118.045 86.841  150.939 1.00 86.39  ?  89  GLU S C   1 
ATOM   5383 O O   . GLU D 4 89  ? 118.869 87.531  151.549 1.00 86.39  ?  89  GLU S O   1 
ATOM   5384 C CB  . GLU D 4 89  ? 119.595 85.167  149.934 1.00 86.39  ?  89  GLU S CB  1 
ATOM   5385 N N   . ASP D 4 90  ? 116.925 87.351  150.432 1.00 82.53  ?  90  ASP S N   1 
ATOM   5386 C CA  . ASP D 4 90  ? 116.613 88.770  150.521 1.00 82.53  ?  90  ASP S CA  1 
ATOM   5387 C C   . ASP D 4 90  ? 115.744 89.123  151.721 1.00 82.53  ?  90  ASP S C   1 
ATOM   5388 O O   . ASP D 4 90  ? 115.413 90.299  151.899 1.00 82.53  ?  90  ASP S O   1 
ATOM   5389 C CB  . ASP D 4 90  ? 115.926 89.238  149.235 1.00 82.53  ?  90  ASP S CB  1 
ATOM   5390 C CG  . ASP D 4 90  ? 116.873 89.280  148.053 1.00 82.53  ?  90  ASP S CG  1 
ATOM   5391 O OD1 . ASP D 4 90  ? 118.051 88.904  148.223 1.00 82.53  ?  90  ASP S OD1 1 
ATOM   5392 O OD2 . ASP D 4 90  ? 116.440 89.687  146.955 1.00 82.53  -1 90  ASP S OD2 1 
ATOM   5393 N N   . THR D 4 91  ? 115.368 88.147  152.545 1.00 82.72  ?  91  THR S N   1 
ATOM   5394 C CA  . THR D 4 91  ? 114.605 88.442  153.752 1.00 82.72  ?  91  THR S CA  1 
ATOM   5395 C C   . THR D 4 91  ? 115.499 89.136  154.775 1.00 82.72  ?  91  THR S C   1 
ATOM   5396 O O   . THR D 4 91  ? 116.557 88.615  155.145 1.00 82.72  ?  91  THR S O   1 
ATOM   5397 C CB  . THR D 4 91  ? 113.989 87.162  154.323 1.00 82.72  ?  91  THR S CB  1 
ATOM   5398 O OG1 . THR D 4 91  ? 113.217 87.473  155.490 1.00 82.72  ?  91  THR S OG1 1 
ATOM   5399 C CG2 . THR D 4 91  ? 115.044 86.110  154.656 1.00 82.72  ?  91  THR S CG2 1 
ATOM   5400 N N   . ALA D 4 92  ? 115.084 90.321  155.217 1.00 78.08  ?  92  ALA S N   1 
ATOM   5401 C CA  . ALA D 4 92  ? 115.905 91.140  156.102 1.00 78.08  ?  92  ALA S CA  1 
ATOM   5402 C C   . ALA D 4 92  ? 115.109 92.373  156.505 1.00 78.08  ?  92  ALA S C   1 
ATOM   5403 O O   . ALA D 4 92  ? 114.041 92.657  155.955 1.00 78.08  ?  92  ALA S O   1 
ATOM   5404 C CB  . ALA D 4 92  ? 117.219 91.561  155.439 1.00 78.08  ?  92  ALA S CB  1 
ATOM   5405 N N   . MET D 4 93  ? 115.648 93.109  157.473 1.00 75.92  ?  93  MET S N   1 
ATOM   5406 C CA  . MET D 4 93  ? 115.147 94.429  157.825 1.00 75.92  ?  93  MET S CA  1 
ATOM   5407 C C   . MET D 4 93  ? 115.980 95.462  157.079 1.00 75.92  ?  93  MET S C   1 
ATOM   5408 O O   . MET D 4 93  ? 117.200 95.523  157.253 1.00 75.92  ?  93  MET S O   1 
ATOM   5409 C CB  . MET D 4 93  ? 115.219 94.665  159.333 1.00 75.92  ?  93  MET S CB  1 
ATOM   5410 C CG  . MET D 4 93  ? 114.600 95.979  159.781 1.00 75.92  ?  93  MET S CG  1 
ATOM   5411 S SD  . MET D 4 93  ? 114.687 96.232  161.564 1.00 75.92  ?  93  MET S SD  1 
ATOM   5412 C CE  . MET D 4 93  ? 113.481 95.044  162.143 1.00 75.92  ?  93  MET S CE  1 
ATOM   5413 N N   . TYR D 4 94  ? 115.326 96.262  156.248 1.00 68.33  ?  94  TYR S N   1 
ATOM   5414 C CA  . TYR D 4 94  ? 116.001 97.266  155.441 1.00 68.33  ?  94  TYR S CA  1 
ATOM   5415 C C   . TYR D 4 94  ? 115.979 98.607  156.158 1.00 68.33  ?  94  TYR S C   1 
ATOM   5416 O O   . TYR D 4 94  ? 114.991 98.958  156.811 1.00 68.33  ?  94  TYR S O   1 
ATOM   5417 C CB  . TYR D 4 94  ? 115.353 97.390  154.061 1.00 68.33  ?  94  TYR S CB  1 
ATOM   5418 C CG  . TYR D 4 94  ? 115.635 96.217  153.147 1.00 68.33  ?  94  TYR S CG  1 
ATOM   5419 C CD1 . TYR D 4 94  ? 115.112 94.959  153.415 1.00 68.33  ?  94  TYR S CD1 1 
ATOM   5420 C CD2 . TYR D 4 94  ? 116.433 96.368  152.022 1.00 68.33  ?  94  TYR S CD2 1 
ATOM   5421 C CE1 . TYR D 4 94  ? 115.372 93.887  152.587 1.00 68.33  ?  94  TYR S CE1 1 
ATOM   5422 C CE2 . TYR D 4 94  ? 116.697 95.301  151.188 1.00 68.33  ?  94  TYR S CE2 1 
ATOM   5423 C CZ  . TYR D 4 94  ? 116.164 94.064  151.475 1.00 68.33  ?  94  TYR S CZ  1 
ATOM   5424 O OH  . TYR D 4 94  ? 116.424 92.997  150.648 1.00 68.33  ?  94  TYR S OH  1 
ATOM   5425 N N   . TYR D 4 95  ? 117.084 99.343  156.045 1.00 63.12  ?  95  TYR S N   1 
ATOM   5426 C CA  . TYR D 4 95  ? 117.276 100.629 156.692 1.00 63.12  ?  95  TYR S CA  1 
ATOM   5427 C C   . TYR D 4 95  ? 117.615 101.682 155.648 1.00 63.12  ?  95  TYR S C   1 
ATOM   5428 O O   . TYR D 4 95  ? 118.355 101.416 154.690 1.00 63.12  ?  95  TYR S O   1 
ATOM   5429 C CB  . TYR D 4 95  ? 118.396 100.570 157.735 1.00 63.12  ?  95  TYR S CB  1 
ATOM   5430 C CG  . TYR D 4 95  ? 118.119 99.659  158.906 1.00 63.12  ?  95  TYR S CG  1 
ATOM   5431 C CD1 . TYR D 4 95  ? 117.306 100.069 159.951 1.00 63.12  ?  95  TYR S CD1 1 
ATOM   5432 C CD2 . TYR D 4 95  ? 118.680 98.393  158.971 1.00 63.12  ?  95  TYR S CD2 1 
ATOM   5433 C CE1 . TYR D 4 95  ? 117.054 99.242  161.025 1.00 63.12  ?  95  TYR S CE1 1 
ATOM   5434 C CE2 . TYR D 4 95  ? 118.434 97.559  160.040 1.00 63.12  ?  95  TYR S CE2 1 
ATOM   5435 C CZ  . TYR D 4 95  ? 117.620 97.988  161.064 1.00 63.12  ?  95  TYR S CZ  1 
ATOM   5436 O OH  . TYR D 4 95  ? 117.372 97.159  162.132 1.00 63.12  ?  95  TYR S OH  1 
ATOM   5437 N N   . CYS D 4 96  ? 117.080 102.877 155.868 1.00 63.69  ?  96  CYS S N   1 
ATOM   5438 C CA  . CYS D 4 96  ? 117.239 104.034 154.999 1.00 63.69  ?  96  CYS S CA  1 
ATOM   5439 C C   . CYS D 4 96  ? 118.182 105.009 155.689 1.00 63.69  ?  96  CYS S C   1 
ATOM   5440 O O   . CYS D 4 96  ? 117.823 105.595 156.716 1.00 63.69  ?  96  CYS S O   1 
ATOM   5441 C CB  . CYS D 4 96  ? 115.873 104.670 154.742 1.00 63.69  ?  96  CYS S CB  1 
ATOM   5442 S SG  . CYS D 4 96  ? 115.759 106.076 153.637 1.00 63.69  ?  96  CYS S SG  1 
ATOM   5443 N N   . VAL D 4 97  ? 119.381 105.178 155.139 1.00 55.09  ?  97  VAL S N   1 
ATOM   5444 C CA  . VAL D 4 97  ? 120.438 105.948 155.782 1.00 55.09  ?  97  VAL S CA  1 
ATOM   5445 C C   . VAL D 4 97  ? 120.739 107.177 154.939 1.00 55.09  ?  97  VAL S C   1 
ATOM   5446 O O   . VAL D 4 97  ? 120.775 107.101 153.707 1.00 55.09  ?  97  VAL S O   1 
ATOM   5447 C CB  . VAL D 4 97  ? 121.712 105.101 155.978 1.00 55.09  ?  97  VAL S CB  1 
ATOM   5448 C CG1 . VAL D 4 97  ? 122.680 105.804 156.910 1.00 55.09  ?  97  VAL S CG1 1 
ATOM   5449 C CG2 . VAL D 4 97  ? 121.356 103.723 156.502 1.00 55.09  ?  97  VAL S CG2 1 
ATOM   5450 N N   . ARG D 4 98  ? 120.946 108.308 155.601 1.00 56.74  ?  98  ARG S N   1 
ATOM   5451 C CA  . ARG D 4 98  ? 121.368 109.529 154.934 1.00 56.74  ?  98  ARG S CA  1 
ATOM   5452 C C   . ARG D 4 98  ? 122.863 109.736 155.137 1.00 56.74  ?  98  ARG S C   1 
ATOM   5453 O O   . ARG D 4 98  ? 123.430 109.335 156.156 1.00 56.74  ?  98  ARG S O   1 
ATOM   5454 C CB  . ARG D 4 98  ? 120.597 110.741 155.461 1.00 56.74  ?  98  ARG S CB  1 
ATOM   5455 C CG  . ARG D 4 98  ? 120.857 111.054 156.921 1.00 56.74  ?  98  ARG S CG  1 
ATOM   5456 C CD  . ARG D 4 98  ? 120.328 112.425 157.293 1.00 56.74  ?  98  ARG S CD  1 
ATOM   5457 N NE  . ARG D 4 98  ? 121.163 113.072 158.297 1.00 56.74  ?  98  ARG S NE  1 
ATOM   5458 C CZ  . ARG D 4 98  ? 120.973 114.303 158.750 1.00 56.74  ?  98  ARG S CZ  1 
ATOM   5459 N NH1 . ARG D 4 98  ? 119.980 115.055 158.309 1.00 56.74  1  98  ARG S NH1 1 
ATOM   5460 N NH2 . ARG D 4 98  ? 121.801 114.791 159.669 1.00 56.74  ?  98  ARG S NH2 1 
ATOM   5461 N N   . SER D 4 99  ? 123.502 110.361 154.152 1.00 52.77  ?  99  SER S N   1 
ATOM   5462 C CA  . SER D 4 99  ? 124.937 110.614 154.224 1.00 52.77  ?  99  SER S CA  1 
ATOM   5463 C C   . SER D 4 99  ? 125.275 111.748 153.273 1.00 52.77  ?  99  SER S C   1 
ATOM   5464 O O   . SER D 4 99  ? 125.028 111.639 152.068 1.00 52.77  ?  99  SER S O   1 
ATOM   5465 C CB  . SER D 4 99  ? 125.731 109.358 153.872 1.00 52.77  ?  99  SER S CB  1 
ATOM   5466 O OG  . SER D 4 99  ? 125.693 109.108 152.479 1.00 52.77  ?  99  SER S OG  1 
ATOM   5467 N N   . ILE D 4 100 ? 125.837 112.828 153.808 1.00 51.47  ?  100 ILE S N   1 
ATOM   5468 C CA  . ILE D 4 100 ? 126.257 113.980 153.021 1.00 51.47  ?  100 ILE S CA  1 
ATOM   5469 C C   . ILE D 4 100 ? 127.779 113.999 152.990 1.00 51.47  ?  100 ILE S C   1 
ATOM   5470 O O   . ILE D 4 100 ? 128.434 113.741 154.007 1.00 51.47  ?  100 ILE S O   1 
ATOM   5471 C CB  . ILE D 4 100 ? 125.682 115.294 153.589 1.00 51.47  ?  100 ILE S CB  1 
ATOM   5472 C CG1 . ILE D 4 100 ? 126.059 116.478 152.700 1.00 51.47  ?  100 ILE S CG1 1 
ATOM   5473 C CG2 . ILE D 4 100 ? 126.134 115.518 155.025 1.00 51.47  ?  100 ILE S CG2 1 
ATOM   5474 C CD1 . ILE D 4 100 ? 125.108 117.643 152.814 1.00 51.47  ?  100 ILE S CD1 1 
ATOM   5475 N N   . TYR D 4 101 ? 128.341 114.275 151.816 1.00 51.49  ?  101 TYR S N   1 
ATOM   5476 C CA  . TYR D 4 101 ? 129.779 114.157 151.593 1.00 51.49  ?  101 TYR S CA  1 
ATOM   5477 C C   . TYR D 4 101 ? 130.363 115.520 151.246 1.00 51.49  ?  101 TYR S C   1 
ATOM   5478 O O   . TYR D 4 101 ? 130.099 116.060 150.168 1.00 51.49  ?  101 TYR S O   1 
ATOM   5479 C CB  . TYR D 4 101 ? 130.075 113.147 150.488 1.00 51.49  ?  101 TYR S CB  1 
ATOM   5480 C CG  . TYR D 4 101 ? 129.635 111.738 150.806 1.00 51.49  ?  101 TYR S CG  1 
ATOM   5481 C CD1 . TYR D 4 101 ? 130.396 110.921 151.628 1.00 51.49  ?  101 TYR S CD1 1 
ATOM   5482 C CD2 . TYR D 4 101 ? 128.459 111.224 150.281 1.00 51.49  ?  101 TYR S CD2 1 
ATOM   5483 C CE1 . TYR D 4 101 ? 129.999 109.634 151.919 1.00 51.49  ?  101 TYR S CE1 1 
ATOM   5484 C CE2 . TYR D 4 101 ? 128.053 109.938 150.567 1.00 51.49  ?  101 TYR S CE2 1 
ATOM   5485 C CZ  . TYR D 4 101 ? 128.826 109.148 151.387 1.00 51.49  ?  101 TYR S CZ  1 
ATOM   5486 O OH  . TYR D 4 101 ? 128.426 107.865 151.676 1.00 51.49  ?  101 TYR S OH  1 
ATOM   5487 N N   . TYR D 4 102 ? 131.156 116.064 152.163 1.00 51.42  ?  102 TYR S N   1 
ATOM   5488 C CA  . TYR D 4 102 ? 132.005 117.219 151.906 1.00 51.42  ?  102 TYR S CA  1 
ATOM   5489 C C   . TYR D 4 102 ? 133.133 117.176 152.928 1.00 51.42  ?  102 TYR S C   1 
ATOM   5490 O O   . TYR D 4 102 ? 133.178 116.291 153.786 1.00 51.42  ?  102 TYR S O   1 
ATOM   5491 C CB  . TYR D 4 102 ? 131.217 118.532 151.961 1.00 51.42  ?  102 TYR S CB  1 
ATOM   5492 C CG  . TYR D 4 102 ? 130.409 118.744 153.221 1.00 51.42  ?  102 TYR S CG  1 
ATOM   5493 C CD1 . TYR D 4 102 ? 130.985 119.301 154.354 1.00 51.42  ?  102 TYR S CD1 1 
ATOM   5494 C CD2 . TYR D 4 102 ? 129.066 118.403 153.272 1.00 51.42  ?  102 TYR S CD2 1 
ATOM   5495 C CE1 . TYR D 4 102 ? 130.249 119.501 155.503 1.00 51.42  ?  102 TYR S CE1 1 
ATOM   5496 C CE2 . TYR D 4 102 ? 128.323 118.600 154.417 1.00 51.42  ?  102 TYR S CE2 1 
ATOM   5497 C CZ  . TYR D 4 102 ? 128.919 119.148 155.529 1.00 51.42  ?  102 TYR S CZ  1 
ATOM   5498 O OH  . TYR D 4 102 ? 128.181 119.346 156.673 1.00 51.42  ?  102 TYR S OH  1 
ATOM   5499 N N   . TYR D 4 103 ? 134.056 118.128 152.826 1.00 52.47  ?  103 TYR S N   1 
ATOM   5500 C CA  . TYR D 4 103 ? 135.190 118.142 153.742 1.00 52.47  ?  103 TYR S CA  1 
ATOM   5501 C C   . TYR D 4 103 ? 134.709 118.364 155.169 1.00 52.47  ?  103 TYR S C   1 
ATOM   5502 O O   . TYR D 4 103 ? 134.036 119.358 155.461 1.00 52.47  ?  103 TYR S O   1 
ATOM   5503 C CB  . TYR D 4 103 ? 136.192 119.224 153.348 1.00 52.47  ?  103 TYR S CB  1 
ATOM   5504 C CG  . TYR D 4 103 ? 137.340 119.335 154.324 1.00 52.47  ?  103 TYR S CG  1 
ATOM   5505 C CD1 . TYR D 4 103 ? 138.319 118.354 154.385 1.00 52.47  ?  103 TYR S CD1 1 
ATOM   5506 C CD2 . TYR D 4 103 ? 137.434 120.408 155.197 1.00 52.47  ?  103 TYR S CD2 1 
ATOM   5507 C CE1 . TYR D 4 103 ? 139.365 118.444 155.280 1.00 52.47  ?  103 TYR S CE1 1 
ATOM   5508 C CE2 . TYR D 4 103 ? 138.477 120.507 156.095 1.00 52.47  ?  103 TYR S CE2 1 
ATOM   5509 C CZ  . TYR D 4 103 ? 139.439 119.523 156.132 1.00 52.47  ?  103 TYR S CZ  1 
ATOM   5510 O OH  . TYR D 4 103 ? 140.480 119.618 157.026 1.00 52.47  ?  103 TYR S OH  1 
ATOM   5511 N N   . GLY D 4 104 ? 135.056 117.437 156.057 1.00 54.96  ?  104 GLY S N   1 
ATOM   5512 C CA  . GLY D 4 104 ? 134.631 117.517 157.437 1.00 54.96  ?  104 GLY S CA  1 
ATOM   5513 C C   . GLY D 4 104 ? 133.225 117.036 157.702 1.00 54.96  ?  104 GLY S C   1 
ATOM   5514 O O   . GLY D 4 104 ? 132.758 117.138 158.842 1.00 54.96  ?  104 GLY S O   1 
ATOM   5515 N N   . SER D 4 105 ? 132.534 116.514 156.692 1.00 54.66  ?  105 SER S N   1 
ATOM   5516 C CA  . SER D 4 105 ? 131.176 116.035 156.882 1.00 54.66  ?  105 SER S CA  1 
ATOM   5517 C C   . SER D 4 105 ? 131.178 114.716 157.649 1.00 54.66  ?  105 SER S C   1 
ATOM   5518 O O   . SER D 4 105 ? 132.217 114.088 157.869 1.00 54.66  ?  105 SER S O   1 
ATOM   5519 C CB  . SER D 4 105 ? 130.474 115.864 155.536 1.00 54.66  ?  105 SER S CB  1 
ATOM   5520 O OG  . SER D 4 105 ? 131.173 114.952 154.710 1.00 54.66  ?  105 SER S OG  1 
ATOM   5521 N N   . SER D 4 106 ? 129.982 114.295 158.060 1.00 55.89  ?  106 SER S N   1 
ATOM   5522 C CA  . SER D 4 106 ? 129.784 113.069 158.830 1.00 55.89  ?  106 SER S CA  1 
ATOM   5523 C C   . SER D 4 106 ? 128.780 112.190 158.098 1.00 55.89  ?  106 SER S C   1 
ATOM   5524 O O   . SER D 4 106 ? 127.564 112.320 158.300 1.00 55.89  ?  106 SER S O   1 
ATOM   5525 C CB  . SER D 4 106 ? 129.311 113.386 160.246 1.00 55.89  ?  106 SER S CB  1 
ATOM   5526 O OG  . SER D 4 106 ? 128.667 112.269 160.828 1.00 55.89  ?  106 SER S OG  1 
ATOM   5527 N N   . PRO D 4 107 ? 129.237 111.298 157.225 1.00 55.06  ?  107 PRO S N   1 
ATOM   5528 C CA  . PRO D 4 107 ? 128.309 110.390 156.544 1.00 55.06  ?  107 PRO S CA  1 
ATOM   5529 C C   . PRO D 4 107 ? 127.670 109.408 157.514 1.00 55.06  ?  107 PRO S C   1 
ATOM   5530 O O   . PRO D 4 107 ? 128.202 109.110 158.585 1.00 55.06  ?  107 PRO S O   1 
ATOM   5531 C CB  . PRO D 4 107 ? 129.199 109.668 155.528 1.00 55.06  ?  107 PRO S CB  1 
ATOM   5532 C CG  . PRO D 4 107 ? 130.369 110.575 155.339 1.00 55.06  ?  107 PRO S CG  1 
ATOM   5533 C CD  . PRO D 4 107 ? 130.599 111.201 156.679 1.00 55.06  ?  107 PRO S CD  1 
ATOM   5534 N N   . PHE D 4 108 ? 126.494 108.916 157.116 1.00 55.39  ?  108 PHE S N   1 
ATOM   5535 C CA  . PHE D 4 108 ? 125.747 107.910 157.874 1.00 55.39  ?  108 PHE S CA  1 
ATOM   5536 C C   . PHE D 4 108 ? 125.301 108.446 159.233 1.00 55.39  ?  108 PHE S C   1 
ATOM   5537 O O   . PHE D 4 108 ? 125.345 107.741 160.241 1.00 55.39  ?  108 PHE S O   1 
ATOM   5538 C CB  . PHE D 4 108 ? 126.558 106.622 158.038 1.00 55.39  ?  108 PHE S CB  1 
ATOM   5539 C CG  . PHE D 4 108 ? 126.708 105.832 156.769 1.00 55.39  ?  108 PHE S CG  1 
ATOM   5540 C CD1 . PHE D 4 108 ? 127.551 106.265 155.761 1.00 55.39  ?  108 PHE S CD1 1 
ATOM   5541 C CD2 . PHE D 4 108 ? 126.007 104.653 156.586 1.00 55.39  ?  108 PHE S CD2 1 
ATOM   5542 C CE1 . PHE D 4 108 ? 127.689 105.542 154.596 1.00 55.39  ?  108 PHE S CE1 1 
ATOM   5543 C CE2 . PHE D 4 108 ? 126.142 103.925 155.422 1.00 55.39  ?  108 PHE S CE2 1 
ATOM   5544 C CZ  . PHE D 4 108 ? 126.982 104.372 154.427 1.00 55.39  ?  108 PHE S CZ  1 
ATOM   5545 N N   . ASP D 4 109 ? 124.863 109.707 159.260 1.00 59.54  ?  109 ASP S N   1 
ATOM   5546 C CA  . ASP D 4 109 ? 124.399 110.311 160.506 1.00 59.54  ?  109 ASP S CA  1 
ATOM   5547 C C   . ASP D 4 109 ? 123.158 109.608 161.040 1.00 59.54  ?  109 ASP S C   1 
ATOM   5548 O O   . ASP D 4 109 ? 123.113 109.193 162.203 1.00 59.54  ?  109 ASP S O   1 
ATOM   5549 C CB  . ASP D 4 109 ? 124.109 111.798 160.298 1.00 59.54  ?  109 ASP S CB  1 
ATOM   5550 C CG  . ASP D 4 109 ? 125.362 112.631 160.221 1.00 59.54  ?  109 ASP S CG  1 
ATOM   5551 O OD1 . ASP D 4 109 ? 126.351 112.277 160.896 1.00 59.54  ?  109 ASP S OD1 1 
ATOM   5552 O OD2 . ASP D 4 109 ? 125.359 113.644 159.491 1.00 59.54  -1 109 ASP S OD2 1 
ATOM   5553 N N   . PHE D 4 110 ? 122.137 109.464 160.201 1.00 59.06  ?  110 PHE S N   1 
ATOM   5554 C CA  . PHE D 4 110 ? 120.819 109.039 160.645 1.00 59.06  ?  110 PHE S CA  1 
ATOM   5555 C C   . PHE D 4 110 ? 120.386 107.785 159.902 1.00 59.06  ?  110 PHE S C   1 
ATOM   5556 O O   . PHE D 4 110 ? 120.586 107.668 158.689 1.00 59.06  ?  110 PHE S O   1 
ATOM   5557 C CB  . PHE D 4 110 ? 119.789 110.152 160.438 1.00 59.06  ?  110 PHE S CB  1 
ATOM   5558 C CG  . PHE D 4 110 ? 118.570 110.014 161.299 1.00 59.06  ?  110 PHE S CG  1 
ATOM   5559 C CD1 . PHE D 4 110 ? 118.612 110.359 162.638 1.00 59.06  ?  110 PHE S CD1 1 
ATOM   5560 C CD2 . PHE D 4 110 ? 117.383 109.539 160.773 1.00 59.06  ?  110 PHE S CD2 1 
ATOM   5561 C CE1 . PHE D 4 110 ? 117.494 110.231 163.434 1.00 59.06  ?  110 PHE S CE1 1 
ATOM   5562 C CE2 . PHE D 4 110 ? 116.262 109.409 161.564 1.00 59.06  ?  110 PHE S CE2 1 
ATOM   5563 C CZ  . PHE D 4 110 ? 116.318 109.756 162.897 1.00 59.06  ?  110 PHE S CZ  1 
ATOM   5564 N N   . TRP D 4 111 ? 119.791 106.853 160.639 1.00 56.51  ?  111 TRP S N   1 
ATOM   5565 C CA  . TRP D 4 111 ? 119.275 105.609 160.091 1.00 56.51  ?  111 TRP S CA  1 
ATOM   5566 C C   . TRP D 4 111 ? 117.768 105.545 160.299 1.00 56.51  ?  111 TRP S C   1 
ATOM   5567 O O   . TRP D 4 111 ? 117.255 106.005 161.323 1.00 56.51  ?  111 TRP S O   1 
ATOM   5568 C CB  . TRP D 4 111 ? 119.937 104.397 160.751 1.00 56.51  ?  111 TRP S CB  1 
ATOM   5569 C CG  . TRP D 4 111 ? 121.384 104.217 160.405 1.00 56.51  ?  111 TRP S CG  1 
ATOM   5570 C CD1 . TRP D 4 111 ? 122.383 105.134 160.549 1.00 56.51  ?  111 TRP S CD1 1 
ATOM   5571 C CD2 . TRP D 4 111 ? 121.996 103.038 159.871 1.00 56.51  ?  111 TRP S CD2 1 
ATOM   5572 N NE1 . TRP D 4 111 ? 123.578 104.602 160.130 1.00 56.51  ?  111 TRP S NE1 1 
ATOM   5573 C CE2 . TRP D 4 111 ? 123.367 103.316 159.709 1.00 56.51  ?  111 TRP S CE2 1 
ATOM   5574 C CE3 . TRP D 4 111 ? 121.517 101.776 159.509 1.00 56.51  ?  111 TRP S CE3 1 
ATOM   5575 C CZ2 . TRP D 4 111 ? 124.263 102.379 159.202 1.00 56.51  ?  111 TRP S CZ2 1 
ATOM   5576 C CZ3 . TRP D 4 111 ? 122.408 100.848 159.007 1.00 56.51  ?  111 TRP S CZ3 1 
ATOM   5577 C CH2 . TRP D 4 111 ? 123.765 101.154 158.858 1.00 56.51  ?  111 TRP S CH2 1 
ATOM   5578 N N   . GLY D 4 112 ? 117.065 104.975 159.329 1.00 64.54  ?  112 GLY S N   1 
ATOM   5579 C CA  . GLY D 4 112 ? 115.637 104.784 159.450 1.00 64.54  ?  112 GLY S CA  1 
ATOM   5580 C C   . GLY D 4 112 ? 115.304 103.694 160.451 1.00 64.54  ?  112 GLY S C   1 
ATOM   5581 O O   . GLY D 4 112 ? 116.169 103.012 161.000 1.00 64.54  ?  112 GLY S O   1 
ATOM   5582 N N   . GLN D 4 113 ? 114.003 103.528 160.690 1.00 72.75  ?  113 GLN S N   1 
ATOM   5583 C CA  . GLN D 4 113 ? 113.550 102.553 161.674 1.00 72.75  ?  113 GLN S CA  1 
ATOM   5584 C C   . GLN D 4 113 ? 113.576 101.124 161.151 1.00 72.75  ?  113 GLN S C   1 
ATOM   5585 O O   . GLN D 4 113 ? 113.528 100.186 161.954 1.00 72.75  ?  113 GLN S O   1 
ATOM   5586 C CB  . GLN D 4 113 ? 112.140 102.903 162.152 1.00 72.75  ?  113 GLN S CB  1 
ATOM   5587 C CG  . GLN D 4 113 ? 112.056 104.230 162.884 1.00 72.75  ?  113 GLN S CG  1 
ATOM   5588 C CD  . GLN D 4 113 ? 112.812 104.214 164.199 1.00 72.75  ?  113 GLN S CD  1 
ATOM   5589 O OE1 . GLN D 4 113 ? 112.802 103.218 164.922 1.00 72.75  ?  113 GLN S OE1 1 
ATOM   5590 N NE2 . GLN D 4 113 ? 113.477 105.320 164.513 1.00 72.75  ?  113 GLN S NE2 1 
ATOM   5591 N N   . GLY D 4 114 ? 113.650 100.933 159.837 1.00 73.38  ?  114 GLY S N   1 
ATOM   5592 C CA  . GLY D 4 114 ? 113.743 99.599  159.279 1.00 73.38  ?  114 GLY S CA  1 
ATOM   5593 C C   . GLY D 4 114 ? 112.403 98.971  158.959 1.00 73.38  ?  114 GLY S C   1 
ATOM   5594 O O   . GLY D 4 114 ? 111.449 99.102  159.731 1.00 73.38  ?  114 GLY S O   1 
ATOM   5595 N N   . THR D 4 115 ? 112.318 98.288  157.819 1.00 76.63  ?  115 THR S N   1 
ATOM   5596 C CA  . THR D 4 115 ? 111.122 97.546  157.437 1.00 76.63  ?  115 THR S CA  1 
ATOM   5597 C C   . THR D 4 115 ? 111.499 96.101  157.165 1.00 76.63  ?  115 THR S C   1 
ATOM   5598 O O   . THR D 4 115 ? 112.487 95.836  156.475 1.00 76.63  ?  115 THR S O   1 
ATOM   5599 C CB  . THR D 4 115 ? 110.449 98.148  156.202 1.00 76.63  ?  115 THR S CB  1 
ATOM   5600 O OG1 . THR D 4 115 ? 111.379 98.181  155.113 1.00 76.63  ?  115 THR S OG1 1 
ATOM   5601 C CG2 . THR D 4 115 ? 109.959 99.543  156.497 1.00 76.63  ?  115 THR S CG2 1 
ATOM   5602 N N   . THR D 4 116 ? 110.717 95.173  157.708 1.00 80.38  ?  116 THR S N   1 
ATOM   5603 C CA  . THR D 4 116 ? 110.985 93.750  157.557 1.00 80.38  ?  116 THR S CA  1 
ATOM   5604 C C   . THR D 4 116 ? 110.371 93.255  156.255 1.00 80.38  ?  116 THR S C   1 
ATOM   5605 O O   . THR D 4 116 ? 109.167 93.421  156.028 1.00 80.38  ?  116 THR S O   1 
ATOM   5606 C CB  . THR D 4 116 ? 110.425 92.961  158.739 1.00 80.38  ?  116 THR S CB  1 
ATOM   5607 O OG1 . THR D 4 116 ? 108.993 92.995  158.700 1.00 80.38  ?  116 THR S OG1 1 
ATOM   5608 C CG2 . THR D 4 116 ? 110.900 93.560  160.050 1.00 80.38  ?  116 THR S CG2 1 
ATOM   5609 N N   . LEU D 4 117 ? 111.195 92.653  155.403 1.00 81.85  ?  117 LEU S N   1 
ATOM   5610 C CA  . LEU D 4 117 ? 110.736 91.989  154.192 1.00 81.85  ?  117 LEU S CA  1 
ATOM   5611 C C   . LEU D 4 117 ? 111.101 90.518  154.308 1.00 81.85  ?  117 LEU S C   1 
ATOM   5612 O O   . LEU D 4 117 ? 112.288 90.172  154.339 1.00 81.85  ?  117 LEU S O   1 
ATOM   5613 C CB  . LEU D 4 117 ? 111.363 92.615  152.946 1.00 81.85  ?  117 LEU S CB  1 
ATOM   5614 C CG  . LEU D 4 117 ? 110.882 92.081  151.597 1.00 81.85  ?  117 LEU S CG  1 
ATOM   5615 C CD1 . LEU D 4 117 ? 110.630 93.227  150.636 1.00 81.85  ?  117 LEU S CD1 1 
ATOM   5616 C CD2 . LEU D 4 117 ? 111.892 91.108  151.015 1.00 81.85  ?  117 LEU S CD2 1 
ATOM   5617 N N   . THR D 4 118 ? 110.087 89.661  154.387 1.00 88.73  ?  118 THR S N   1 
ATOM   5618 C CA  . THR D 4 118 ? 110.280 88.230  154.579 1.00 88.73  ?  118 THR S CA  1 
ATOM   5619 C C   . THR D 4 118 ? 109.836 87.498  153.323 1.00 88.73  ?  118 THR S C   1 
ATOM   5620 O O   . THR D 4 118 ? 108.690 87.644  152.887 1.00 88.73  ?  118 THR S O   1 
ATOM   5621 C CB  . THR D 4 118 ? 109.502 87.728  155.795 1.00 88.73  ?  118 THR S CB  1 
ATOM   5622 O OG1 . THR D 4 118 ? 109.806 88.546  156.931 1.00 88.73  ?  118 THR S OG1 1 
ATOM   5623 C CG2 . THR D 4 118 ? 109.872 86.286  156.103 1.00 88.73  ?  118 THR S CG2 1 
ATOM   5624 N N   . VAL D 4 119 ? 110.738 86.708  152.752 1.00 91.42  ?  119 VAL S N   1 
ATOM   5625 C CA  . VAL D 4 119 ? 110.442 85.920  151.563 1.00 91.42  ?  119 VAL S CA  1 
ATOM   5626 C C   . VAL D 4 119 ? 110.012 84.531  152.011 1.00 91.42  ?  119 VAL S C   1 
ATOM   5627 O O   . VAL D 4 119 ? 110.744 83.845  152.732 1.00 91.42  ?  119 VAL S O   1 
ATOM   5628 C CB  . VAL D 4 119 ? 111.656 85.853  150.626 1.00 91.42  ?  119 VAL S CB  1 
ATOM   5629 C CG1 . VAL D 4 119 ? 111.338 85.006  149.407 1.00 91.42  ?  119 VAL S CG1 1 
ATOM   5630 C CG2 . VAL D 4 119 ? 112.073 87.254  150.213 1.00 91.42  ?  119 VAL S CG2 1 
ATOM   5631 N N   . SER D 4 120 ? 108.822 84.117  151.586 1.00 97.75  ?  120 SER S N   1 
ATOM   5632 C CA  . SER D 4 120 ? 108.236 82.854  152.030 1.00 97.75  ?  120 SER S CA  1 
ATOM   5633 C C   . SER D 4 120 ? 108.976 81.698  151.369 1.00 97.75  ?  120 SER S C   1 
ATOM   5634 O O   . SER D 4 120 ? 108.666 81.310  150.241 1.00 97.75  ?  120 SER S O   1 
ATOM   5635 C CB  . SER D 4 120 ? 106.748 82.815  151.703 1.00 97.75  ?  120 SER S CB  1 
ATOM   5636 O OG  . SER D 4 120 ? 106.534 82.699  150.307 1.00 97.75  ?  120 SER S OG  1 
ATOM   5637 N N   . SER D 4 121 ? 109.957 81.146  152.080 1.00 101.25 ?  121 SER S N   1 
ATOM   5638 C CA  . SER D 4 121 ? 110.751 80.014  151.605 1.00 101.25 ?  121 SER S CA  1 
ATOM   5639 C C   . SER D 4 121 ? 111.406 80.300  150.256 1.00 101.25 ?  121 SER S C   1 
ATOM   5640 O O   . SER D 4 121 ? 111.523 79.412  149.412 1.00 101.25 ?  121 SER S O   1 
ATOM   5641 C CB  . SER D 4 121 ? 109.886 78.753  151.511 1.00 101.25 ?  121 SER S CB  1 
ATOM   5642 N N   . SER D 4 136 ? 139.312 94.547  146.139 1.00 89.41  ?  136 SER S N   1 
ATOM   5643 C CA  . SER D 4 136 ? 137.954 94.128  145.814 1.00 89.41  ?  136 SER S CA  1 
ATOM   5644 C C   . SER D 4 136 ? 137.289 93.449  147.005 1.00 89.41  ?  136 SER S C   1 
ATOM   5645 O O   . SER D 4 136 ? 137.756 92.411  147.475 1.00 89.41  ?  136 SER S O   1 
ATOM   5646 C CB  . SER D 4 136 ? 137.958 93.186  144.608 1.00 89.41  ?  136 SER S CB  1 
ATOM   5647 N N   . ASP D 4 137 ? 136.195 94.046  147.486 1.00 89.81  ?  137 ASP S N   1 
ATOM   5648 C CA  . ASP D 4 137 ? 135.409 93.513  148.599 1.00 89.81  ?  137 ASP S CA  1 
ATOM   5649 C C   . ASP D 4 137 ? 136.278 93.345  149.850 1.00 89.81  ?  137 ASP S C   1 
ATOM   5650 O O   . ASP D 4 137 ? 136.557 92.237  150.313 1.00 89.81  ?  137 ASP S O   1 
ATOM   5651 C CB  . ASP D 4 137 ? 134.728 92.196  148.207 1.00 89.81  ?  137 ASP S CB  1 
ATOM   5652 C CG  . ASP D 4 137 ? 133.633 92.392  147.179 1.00 89.81  ?  137 ASP S CG  1 
ATOM   5653 O OD1 . ASP D 4 137 ? 133.019 93.479  147.165 1.00 89.81  ?  137 ASP S OD1 1 
ATOM   5654 O OD2 . ASP D 4 137 ? 133.384 91.460  146.386 1.00 89.81  -1 137 ASP S OD2 1 
ATOM   5655 N N   . ILE D 4 138 ? 136.727 94.495  150.362 1.00 77.62  ?  138 ILE S N   1 
ATOM   5656 C CA  . ILE D 4 138 ? 137.501 94.526  151.597 1.00 77.62  ?  138 ILE S CA  1 
ATOM   5657 C C   . ILE D 4 138 ? 136.757 93.768  152.683 1.00 77.62  ?  138 ILE S C   1 
ATOM   5658 O O   . ILE D 4 138 ? 135.560 93.980  152.901 1.00 77.62  ?  138 ILE S O   1 
ATOM   5659 C CB  . ILE D 4 138 ? 137.775 95.980  152.020 1.00 77.62  ?  138 ILE S CB  1 
ATOM   5660 C CG1 . ILE D 4 138 ? 138.547 96.724  150.933 1.00 77.62  ?  138 ILE S CG1 1 
ATOM   5661 C CG2 . ILE D 4 138 ? 138.537 96.021  153.334 1.00 77.62  ?  138 ILE S CG2 1 
ATOM   5662 C CD1 . ILE D 4 138 ? 138.773 98.181  151.254 1.00 77.62  ?  138 ILE S CD1 1 
ATOM   5663 N N   . VAL D 4 139 ? 137.466 92.877  153.368 1.00 78.86  ?  139 VAL S N   1 
ATOM   5664 C CA  . VAL D 4 139 ? 136.880 92.022  154.391 1.00 78.86  ?  139 VAL S CA  1 
ATOM   5665 C C   . VAL D 4 139 ? 137.152 92.647  155.751 1.00 78.86  ?  139 VAL S C   1 
ATOM   5666 O O   . VAL D 4 139 ? 138.309 92.893  156.110 1.00 78.86  ?  139 VAL S O   1 
ATOM   5667 C CB  . VAL D 4 139 ? 137.443 90.594  154.318 1.00 78.86  ?  139 VAL S CB  1 
ATOM   5668 C CG1 . VAL D 4 139 ? 136.898 89.751  155.460 1.00 78.86  ?  139 VAL S CG1 1 
ATOM   5669 C CG2 . VAL D 4 139 ? 137.112 89.964  152.976 1.00 78.86  ?  139 VAL S CG2 1 
ATOM   5670 N N   . MET D 4 140 ? 136.089 92.903  156.507 1.00 77.06  ?  140 MET S N   1 
ATOM   5671 C CA  . MET D 4 140 ? 136.186 93.461  157.849 1.00 77.06  ?  140 MET S CA  1 
ATOM   5672 C C   . MET D 4 140 ? 135.965 92.337  158.851 1.00 77.06  ?  140 MET S C   1 
ATOM   5673 O O   . MET D 4 140 ? 134.938 91.653  158.804 1.00 77.06  ?  140 MET S O   1 
ATOM   5674 C CB  . MET D 4 140 ? 135.162 94.577  158.054 1.00 77.06  ?  140 MET S CB  1 
ATOM   5675 C CG  . MET D 4 140 ? 135.197 95.659  156.987 1.00 77.06  ?  140 MET S CG  1 
ATOM   5676 S SD  . MET D 4 140 ? 136.809 96.443  156.829 1.00 77.06  ?  140 MET S SD  1 
ATOM   5677 C CE  . MET D 4 140 ? 136.911 97.311  158.388 1.00 77.06  ?  140 MET S CE  1 
ATOM   5678 N N   . THR D 4 141 ? 136.925 92.149  159.752 1.00 83.42  ?  141 THR S N   1 
ATOM   5679 C CA  . THR D 4 141 ? 136.883 91.075  160.733 1.00 83.42  ?  141 THR S CA  1 
ATOM   5680 C C   . THR D 4 141 ? 136.950 91.657  162.137 1.00 83.42  ?  141 THR S C   1 
ATOM   5681 O O   . THR D 4 141 ? 137.738 92.569  162.404 1.00 83.42  ?  141 THR S O   1 
ATOM   5682 C CB  . THR D 4 141 ? 138.038 90.089  160.524 1.00 83.42  ?  141 THR S CB  1 
ATOM   5683 O OG1 . THR D 4 141 ? 138.102 89.713  159.142 1.00 83.42  ?  141 THR S OG1 1 
ATOM   5684 C CG2 . THR D 4 141 ? 137.836 88.843  161.371 1.00 83.42  ?  141 THR S CG2 1 
ATOM   5685 N N   . GLN D 4 142 ? 136.117 91.127  163.033 1.00 86.81  ?  142 GLN S N   1 
ATOM   5686 C CA  . GLN D 4 142 ? 136.086 91.575  164.417 1.00 86.81  ?  142 GLN S CA  1 
ATOM   5687 C C   . GLN D 4 142 ? 136.411 90.478  165.420 1.00 86.81  ?  142 GLN S C   1 
ATOM   5688 O O   . GLN D 4 142 ? 136.399 90.749  166.627 1.00 86.81  ?  142 GLN S O   1 
ATOM   5689 C CB  . GLN D 4 142 ? 134.717 92.177  164.754 1.00 86.81  ?  142 GLN S CB  1 
ATOM   5690 C CG  . GLN D 4 142 ? 134.415 93.462  164.013 1.00 86.81  ?  142 GLN S CG  1 
ATOM   5691 C CD  . GLN D 4 142 ? 133.062 94.034  164.369 1.00 86.81  ?  142 GLN S CD  1 
ATOM   5692 O OE1 . GLN D 4 142 ? 132.307 93.439  165.135 1.00 86.81  ?  142 GLN S OE1 1 
ATOM   5693 N NE2 . GLN D 4 142 ? 132.746 95.195  163.813 1.00 86.81  ?  142 GLN S NE2 1 
ATOM   5694 N N   . ALA D 4 143 ? 136.615 89.269  164.932 1.00 95.90  ?  143 ALA S N   1 
ATOM   5695 C CA  . ALA D 4 143 ? 136.923 88.173  165.816 1.00 95.90  ?  143 ALA S CA  1 
ATOM   5696 C C   . ALA D 4 143 ? 135.859 88.182  166.879 1.00 95.90  ?  143 ALA S C   1 
ATOM   5697 O O   . ALA D 4 143 ? 134.672 88.127  166.572 1.00 95.90  ?  143 ALA S O   1 
ATOM   5698 C CB  . ALA D 4 143 ? 138.284 88.379  166.446 1.00 95.90  ?  143 ALA S CB  1 
ATOM   5699 N N   . THR D 4 144 ? 136.268 88.278  168.133 1.00 98.87  ?  144 THR S N   1 
ATOM   5700 C CA  . THR D 4 144 ? 135.298 88.177  169.217 1.00 98.87  ?  144 THR S CA  1 
ATOM   5701 C C   . THR D 4 144 ? 133.928 88.817  169.029 1.00 98.87  ?  144 THR S C   1 
ATOM   5702 O O   . THR D 4 144 ? 133.814 90.021  168.789 1.00 98.87  ?  144 THR S O   1 
ATOM   5703 C CB  . THR D 4 144 ? 135.845 88.818  170.495 1.00 98.87  ?  144 THR S CB  1 
ATOM   5704 O OG1 . THR D 4 144 ? 137.214 88.436  170.676 1.00 98.87  ?  144 THR S OG1 1 
ATOM   5705 C CG2 . THR D 4 144 ? 135.037 88.373  171.705 1.00 98.87  ?  144 THR S CG2 1 
ATOM   5706 N N   . SER D 4 145 ? 132.885 87.994  169.129 1.00 98.76  ?  145 SER S N   1 
ATOM   5707 C CA  . SER D 4 145 ? 131.510 88.451  168.978 1.00 98.76  ?  145 SER S CA  1 
ATOM   5708 C C   . SER D 4 145 ? 130.738 88.809  170.238 1.00 98.76  ?  145 SER S C   1 
ATOM   5709 O O   . SER D 4 145 ? 129.807 89.613  170.165 1.00 98.76  ?  145 SER S O   1 
ATOM   5710 C CB  . SER D 4 145 ? 130.743 87.357  168.224 1.00 98.76  ?  145 SER S CB  1 
ATOM   5711 O OG  . SER D 4 145 ? 131.386 87.033  167.004 1.00 98.76  ?  145 SER S OG  1 
ATOM   5712 N N   . SER D 4 146 ? 131.093 88.233  171.385 1.00 104.74 ?  146 SER S N   1 
ATOM   5713 C CA  . SER D 4 146 ? 130.406 88.503  172.641 1.00 104.74 ?  146 SER S CA  1 
ATOM   5714 C C   . SER D 4 146 ? 131.429 88.869  173.705 1.00 104.74 ?  146 SER S C   1 
ATOM   5715 O O   . SER D 4 146 ? 132.411 88.146  173.901 1.00 104.74 ?  146 SER S O   1 
ATOM   5716 C CB  . SER D 4 146 ? 129.579 87.294  173.092 1.00 104.74 ?  146 SER S CB  1 
ATOM   5717 O OG  . SER D 4 146 ? 128.808 87.604  174.239 1.00 104.74 ?  146 SER S OG  1 
ATOM   5718 N N   . VAL D 4 147 ? 131.198 89.987  174.387 1.00 108.34 ?  147 VAL S N   1 
ATOM   5719 C CA  . VAL D 4 147 ? 132.087 90.450  175.451 1.00 108.34 ?  147 VAL S CA  1 
ATOM   5720 C C   . VAL D 4 147 ? 131.251 90.827  176.668 1.00 108.34 ?  147 VAL S C   1 
ATOM   5721 O O   . VAL D 4 147 ? 130.617 91.892  176.677 1.00 108.34 ?  147 VAL S O   1 
ATOM   5722 C CB  . VAL D 4 147 ? 132.948 91.636  174.986 1.00 108.34 ?  147 VAL S CB  1 
ATOM   5723 C CG1 . VAL D 4 147 ? 133.788 92.164  176.138 1.00 108.34 ?  147 VAL S CG1 1 
ATOM   5724 C CG2 . VAL D 4 147 ? 133.838 91.231  173.821 1.00 108.34 ?  147 VAL S CG2 1 
ATOM   5725 N N   . PRO D 4 148 ? 131.209 89.992  177.709 1.00 112.60 ?  148 PRO S N   1 
ATOM   5726 C CA  . PRO D 4 148 ? 130.454 90.356  178.915 1.00 112.60 ?  148 PRO S CA  1 
ATOM   5727 C C   . PRO D 4 148 ? 131.281 91.187  179.883 1.00 112.60 ?  148 PRO S C   1 
ATOM   5728 O O   . PRO D 4 148 ? 132.295 90.713  180.404 1.00 112.60 ?  148 PRO S O   1 
ATOM   5729 C CB  . PRO D 4 148 ? 130.078 88.996  179.518 1.00 112.60 ?  148 PRO S CB  1 
ATOM   5730 C CG  . PRO D 4 148 ? 131.040 87.992  178.897 1.00 112.60 ?  148 PRO S CG  1 
ATOM   5731 C CD  . PRO D 4 148 ? 131.869 88.685  177.848 1.00 112.60 ?  148 PRO S CD  1 
ATOM   5732 N N   . VAL D 4 149 ? 130.861 92.426  180.132 1.00 115.87 ?  149 VAL S N   1 
ATOM   5733 C CA  . VAL D 4 149 ? 131.570 93.331  181.029 1.00 115.87 ?  149 VAL S CA  1 
ATOM   5734 C C   . VAL D 4 149 ? 130.554 94.040  181.914 1.00 115.87 ?  149 VAL S C   1 
ATOM   5735 O O   . VAL D 4 149 ? 129.518 94.512  181.435 1.00 115.87 ?  149 VAL S O   1 
ATOM   5736 C CB  . VAL D 4 149 ? 132.427 94.353  180.251 1.00 115.87 ?  149 VAL S CB  1 
ATOM   5737 C CG1 . VAL D 4 149 ? 132.987 95.408  181.192 1.00 115.87 ?  149 VAL S CG1 1 
ATOM   5738 C CG2 . VAL D 4 149 ? 133.556 93.651  179.513 1.00 115.87 ?  149 VAL S CG2 1 
ATOM   5739 N N   . THR D 4 150 ? 130.853 94.110  183.210 1.00 118.74 ?  150 THR S N   1 
ATOM   5740 C CA  . THR D 4 150 ? 129.999 94.830  184.138 1.00 118.74 ?  150 THR S CA  1 
ATOM   5741 C C   . THR D 4 150 ? 130.058 96.332  183.858 1.00 118.74 ?  150 THR S C   1 
ATOM   5742 O O   . THR D 4 150 ? 131.083 96.848  183.402 1.00 118.74 ?  150 THR S O   1 
ATOM   5743 C CB  . THR D 4 150 ? 130.422 94.547  185.580 1.00 118.74 ?  150 THR S CB  1 
ATOM   5744 O OG1 . THR D 4 150 ? 129.588 95.281  186.486 1.00 118.74 ?  150 THR S OG1 1 
ATOM   5745 C CG2 . THR D 4 150 ? 131.877 94.938  185.803 1.00 118.74 ?  150 THR S CG2 1 
ATOM   5746 N N   . PRO D 4 151 ? 128.962 97.053  184.099 1.00 117.49 ?  151 PRO S N   1 
ATOM   5747 C CA  . PRO D 4 151 ? 128.973 98.503  183.873 1.00 117.49 ?  151 PRO S CA  1 
ATOM   5748 C C   . PRO D 4 151 ? 130.001 99.205  184.748 1.00 117.49 ?  151 PRO S C   1 
ATOM   5749 O O   . PRO D 4 151 ? 130.271 98.799  185.880 1.00 117.49 ?  151 PRO S O   1 
ATOM   5750 C CB  . PRO D 4 151 ? 127.547 98.931  184.237 1.00 117.49 ?  151 PRO S CB  1 
ATOM   5751 C CG  . PRO D 4 151 ? 126.726 97.705  184.043 1.00 117.49 ?  151 PRO S CG  1 
ATOM   5752 C CD  . PRO D 4 151 ? 127.613 96.553  184.415 1.00 117.49 ?  151 PRO S CD  1 
ATOM   5753 N N   . GLY D 4 152 ? 130.577 100.275 184.202 1.00 112.46 ?  152 GLY S N   1 
ATOM   5754 C CA  . GLY D 4 152 ? 131.567 101.068 184.898 1.00 112.46 ?  152 GLY S CA  1 
ATOM   5755 C C   . GLY D 4 152 ? 133.001 100.810 184.486 1.00 112.46 ?  152 GLY S C   1 
ATOM   5756 O O   . GLY D 4 152 ? 133.881 101.601 184.846 1.00 112.46 ?  152 GLY S O   1 
ATOM   5757 N N   . GLU D 4 153 ? 133.263 99.736  183.745 1.00 109.57 ?  153 GLU S N   1 
ATOM   5758 C CA  . GLU D 4 153 ? 134.614 99.409  183.321 1.00 109.57 ?  153 GLU S CA  1 
ATOM   5759 C C   . GLU D 4 153 ? 134.888 99.979  181.929 1.00 109.57 ?  153 GLU S C   1 
ATOM   5760 O O   . GLU D 4 153 ? 134.051 100.655 181.326 1.00 109.57 ?  153 GLU S O   1 
ATOM   5761 C CB  . GLU D 4 153 ? 134.827 97.896  183.348 1.00 109.57 ?  153 GLU S CB  1 
ATOM   5762 N N   . SER D 4 154 ? 136.081 99.700  181.413 1.00 104.80 ?  154 SER S N   1 
ATOM   5763 C CA  . SER D 4 154 ? 136.503 100.144 180.091 1.00 104.80 ?  154 SER S CA  1 
ATOM   5764 C C   . SER D 4 154 ? 136.601 98.939  179.169 1.00 104.80 ?  154 SER S C   1 
ATOM   5765 O O   . SER D 4 154 ? 137.153 97.902  179.553 1.00 104.80 ?  154 SER S O   1 
ATOM   5766 C CB  . SER D 4 154 ? 137.846 100.873 180.160 1.00 104.80 ?  154 SER S CB  1 
ATOM   5767 O OG  . SER D 4 154 ? 138.176 101.453 178.910 1.00 104.80 ?  154 SER S OG  1 
ATOM   5768 N N   . VAL D 4 155 ? 136.068 99.074  177.956 1.00 99.71  ?  155 VAL S N   1 
ATOM   5769 C CA  . VAL D 4 155 ? 135.994 97.974  177.003 1.00 99.71  ?  155 VAL S CA  1 
ATOM   5770 C C   . VAL D 4 155 ? 136.633 98.411  175.693 1.00 99.71  ?  155 VAL S C   1 
ATOM   5771 O O   . VAL D 4 155 ? 136.345 99.503  175.191 1.00 99.71  ?  155 VAL S O   1 
ATOM   5772 C CB  . VAL D 4 155 ? 134.541 97.518  176.768 1.00 99.71  ?  155 VAL S CB  1 
ATOM   5773 C CG1 . VAL D 4 155 ? 134.485 96.444  175.693 1.00 99.71  ?  155 VAL S CG1 1 
ATOM   5774 C CG2 . VAL D 4 155 ? 133.940 97.006  178.059 1.00 99.71  ?  155 VAL S CG2 1 
ATOM   5775 N N   . SER D 4 156 ? 137.494 97.560  175.144 1.00 93.43  ?  156 SER S N   1 
ATOM   5776 C CA  . SER D 4 156 ? 138.122 97.789  173.851 1.00 93.43  ?  156 SER S CA  1 
ATOM   5777 C C   . SER D 4 156 ? 137.563 96.796  172.842 1.00 93.43  ?  156 SER S C   1 
ATOM   5778 O O   . SER D 4 156 ? 137.545 95.587  173.098 1.00 93.43  ?  156 SER S O   1 
ATOM   5779 C CB  . SER D 4 156 ? 139.643 97.651  173.947 1.00 93.43  ?  156 SER S CB  1 
ATOM   5780 O OG  . SER D 4 156 ? 140.252 97.843  172.682 1.00 93.43  ?  156 SER S OG  1 
ATOM   5781 N N   . ILE D 4 157 ? 137.109 97.309  171.702 1.00 87.15  ?  157 ILE S N   1 
ATOM   5782 C CA  . ILE D 4 157 ? 136.518 96.505  170.640 1.00 87.15  ?  157 ILE S CA  1 
ATOM   5783 C C   . ILE D 4 157 ? 137.426 96.605  169.424 1.00 87.15  ?  157 ILE S C   1 
ATOM   5784 O O   . ILE D 4 157 ? 137.764 97.712  168.988 1.00 87.15  ?  157 ILE S O   1 
ATOM   5785 C CB  . ILE D 4 157 ? 135.092 96.978  170.308 1.00 87.15  ?  157 ILE S CB  1 
ATOM   5786 C CG1 . ILE D 4 157 ? 134.132 96.594  171.434 1.00 87.15  ?  157 ILE S CG1 1 
ATOM   5787 C CG2 . ILE D 4 157 ? 134.626 96.386  168.990 1.00 87.15  ?  157 ILE S CG2 1 
ATOM   5788 C CD1 . ILE D 4 157 ? 133.727 95.145  171.428 1.00 87.15  ?  157 ILE S CD1 1 
ATOM   5789 N N   . SER D 4 158 ? 137.819 95.459  168.879 1.00 86.15  ?  158 SER S N   1 
ATOM   5790 C CA  . SER D 4 158 ? 138.817 95.402  167.822 1.00 86.15  ?  158 SER S CA  1 
ATOM   5791 C C   . SER D 4 158 ? 138.172 95.168  166.462 1.00 86.15  ?  158 SER S C   1 
ATOM   5792 O O   . SER D 4 158 ? 137.095 94.576  166.354 1.00 86.15  ?  158 SER S O   1 
ATOM   5793 C CB  . SER D 4 158 ? 139.838 94.297  168.103 1.00 86.15  ?  158 SER S CB  1 
ATOM   5794 O OG  . SER D 4 158 ? 139.247 93.015  167.974 1.00 86.15  ?  158 SER S OG  1 
ATOM   5795 N N   . CYS D 4 159 ? 138.848 95.647  165.419 1.00 83.42  ?  159 CYS S N   1 
ATOM   5796 C CA  . CYS D 4 159 ? 138.422 95.433  164.045 1.00 83.42  ?  159 CYS S CA  1 
ATOM   5797 C C   . CYS D 4 159 ? 139.655 95.401  163.152 1.00 83.42  ?  159 CYS S C   1 
ATOM   5798 O O   . CYS D 4 159 ? 140.661 96.061  163.431 1.00 83.42  ?  159 CYS S O   1 
ATOM   5799 C CB  . CYS D 4 159 ? 137.444 96.520  163.578 1.00 83.42  ?  159 CYS S CB  1 
ATOM   5800 S SG  . CYS D 4 159 ? 136.817 96.309  161.888 1.00 83.42  ?  159 CYS S SG  1 
ATOM   5801 N N   . ARG D 4 160 ? 139.571 94.615  162.082 1.00 85.16  ?  160 ARG S N   1 
ATOM   5802 C CA  . ARG D 4 160 ? 140.655 94.486  161.121 1.00 85.16  ?  160 ARG S CA  1 
ATOM   5803 C C   . ARG D 4 160 ? 140.089 94.507  159.711 1.00 85.16  ?  160 ARG S C   1 
ATOM   5804 O O   . ARG D 4 160 ? 138.927 94.160  159.486 1.00 85.16  ?  160 ARG S O   1 
ATOM   5805 C CB  . ARG D 4 160 ? 141.456 93.195  161.337 1.00 85.16  ?  160 ARG S CB  1 
ATOM   5806 C CG  . ARG D 4 160 ? 142.260 93.168  162.624 1.00 85.16  ?  160 ARG S CG  1 
ATOM   5807 C CD  . ARG D 4 160 ? 143.080 91.894  162.729 1.00 85.16  ?  160 ARG S CD  1 
ATOM   5808 N NE  . ARG D 4 160 ? 142.242 90.718  162.924 1.00 85.16  ?  160 ARG S NE  1 
ATOM   5809 C CZ  . ARG D 4 160 ? 142.098 89.746  162.034 1.00 85.16  ?  160 ARG S CZ  1 
ATOM   5810 N NH1 . ARG D 4 160 ? 142.722 89.779  160.868 1.00 85.16  1  160 ARG S NH1 1 
ATOM   5811 N NH2 . ARG D 4 160 ? 141.307 88.715  162.320 1.00 85.16  ?  160 ARG S NH2 1 
ATOM   5812 N N   . SER D 4 161 ? 140.923 94.915  158.760 1.00 80.56  ?  161 SER S N   1 
ATOM   5813 C CA  . SER D 4 161 ? 140.538 94.975  157.359 1.00 80.56  ?  161 SER S CA  1 
ATOM   5814 C C   . SER D 4 161 ? 141.560 94.229  156.516 1.00 80.56  ?  161 SER S C   1 
ATOM   5815 O O   . SER D 4 161 ? 142.749 94.194  156.840 1.00 80.56  ?  161 SER S O   1 
ATOM   5816 C CB  . SER D 4 161 ? 140.417 96.425  156.871 1.00 80.56  ?  161 SER S CB  1 
ATOM   5817 O OG  . SER D 4 161 ? 141.692 97.025  156.736 1.00 80.56  ?  161 SER S OG  1 
ATOM   5818 N N   . SER D 4 162 ? 141.081 93.625  155.426 1.00 80.35  ?  162 SER S N   1 
ATOM   5819 C CA  . SER D 4 162 ? 141.986 92.932  154.516 1.00 80.35  ?  162 SER S CA  1 
ATOM   5820 C C   . SER D 4 162 ? 142.925 93.904  153.816 1.00 80.35  ?  162 SER S C   1 
ATOM   5821 O O   . SER D 4 162 ? 144.089 93.571  153.569 1.00 80.35  ?  162 SER S O   1 
ATOM   5822 C CB  . SER D 4 162 ? 141.189 92.131  153.488 1.00 80.35  ?  162 SER S CB  1 
ATOM   5823 O OG  . SER D 4 162 ? 140.744 92.961  152.430 1.00 80.35  ?  162 SER S OG  1 
ATOM   5824 N N   . LYS D 4 163 ? 142.443 95.099  153.491 1.00 78.28  ?  163 LYS S N   1 
ATOM   5825 C CA  . LYS D 4 163 ? 143.238 96.125  152.835 1.00 78.28  ?  163 LYS S CA  1 
ATOM   5826 C C   . LYS D 4 163 ? 143.301 97.357  153.726 1.00 78.28  ?  163 LYS S C   1 
ATOM   5827 O O   . LYS D 4 163 ? 142.321 97.701  154.393 1.00 78.28  ?  163 LYS S O   1 
ATOM   5828 C CB  . LYS D 4 163 ? 142.650 96.482  151.464 1.00 78.28  ?  163 LYS S CB  1 
ATOM   5829 C CG  . LYS D 4 163 ? 143.284 97.692  150.802 1.00 78.28  ?  163 LYS S CG  1 
ATOM   5830 C CD  . LYS D 4 163 ? 142.845 97.831  149.356 1.00 78.28  ?  163 LYS S CD  1 
ATOM   5831 C CE  . LYS D 4 163 ? 143.099 99.237  148.843 1.00 78.28  ?  163 LYS S CE  1 
ATOM   5832 N NZ  . LYS D 4 163 ? 142.503 99.453  147.498 1.00 78.28  1  163 LYS S NZ  1 
ATOM   5833 N N   . SER D 4 164 ? 144.463 98.009  153.744 1.00 77.46  ?  164 SER S N   1 
ATOM   5834 C CA  . SER D 4 164 ? 144.645 99.200  154.563 1.00 77.46  ?  164 SER S CA  1 
ATOM   5835 C C   . SER D 4 164 ? 143.670 100.292 154.143 1.00 77.46  ?  164 SER S C   1 
ATOM   5836 O O   . SER D 4 164 ? 143.520 100.585 152.954 1.00 77.46  ?  164 SER S O   1 
ATOM   5837 C CB  . SER D 4 164 ? 146.083 99.703  154.448 1.00 77.46  ?  164 SER S CB  1 
ATOM   5838 O OG  . SER D 4 164 ? 146.240 100.952 155.096 1.00 77.46  ?  164 SER S OG  1 
ATOM   5839 N N   . LEU D 4 165 ? 143.010 100.897 155.127 1.00 71.24  ?  165 LEU S N   1 
ATOM   5840 C CA  . LEU D 4 165 ? 142.002 101.918 154.882 1.00 71.24  ?  165 LEU S CA  1 
ATOM   5841 C C   . LEU D 4 165 ? 142.565 103.333 154.913 1.00 71.24  ?  165 LEU S C   1 
ATOM   5842 O O   . LEU D 4 165 ? 141.798 104.290 154.773 1.00 71.24  ?  165 LEU S O   1 
ATOM   5843 C CB  . LEU D 4 165 ? 140.870 101.795 155.907 1.00 71.24  ?  165 LEU S CB  1 
ATOM   5844 C CG  . LEU D 4 165 ? 140.096 100.476 155.889 1.00 71.24  ?  165 LEU S CG  1 
ATOM   5845 C CD1 . LEU D 4 165 ? 139.012 100.477 156.950 1.00 71.24  ?  165 LEU S CD1 1 
ATOM   5846 C CD2 . LEU D 4 165 ? 139.503 100.227 154.516 1.00 71.24  ?  165 LEU S CD2 1 
ATOM   5847 N N   . LEU D 4 166 ? 143.873 103.490 155.093 1.00 73.19  ?  166 LEU S N   1 
ATOM   5848 C CA  . LEU D 4 166 ? 144.491 104.810 155.139 1.00 73.19  ?  166 LEU S CA  1 
ATOM   5849 C C   . LEU D 4 166 ? 144.764 105.278 153.715 1.00 73.19  ?  166 LEU S C   1 
ATOM   5850 O O   . LEU D 4 166 ? 145.701 104.803 153.066 1.00 73.19  ?  166 LEU S O   1 
ATOM   5851 C CB  . LEU D 4 166 ? 145.774 104.770 155.964 1.00 73.19  ?  166 LEU S CB  1 
ATOM   5852 C CG  . LEU D 4 166 ? 146.342 106.113 156.425 1.00 73.19  ?  166 LEU S CG  1 
ATOM   5853 C CD1 . LEU D 4 166 ? 146.917 105.993 157.826 1.00 73.19  ?  166 LEU S CD1 1 
ATOM   5854 C CD2 . LEU D 4 166 ? 147.400 106.616 155.457 1.00 73.19  ?  166 LEU S CD2 1 
ATOM   5855 N N   . HIS D 4 167 ? 143.947 106.206 153.228 1.00 73.26  ?  167 HIS S N   1 
ATOM   5856 C CA  . HIS D 4 167 ? 144.117 106.748 151.891 1.00 73.26  ?  167 HIS S CA  1 
ATOM   5857 C C   . HIS D 4 167 ? 145.252 107.770 151.870 1.00 73.26  ?  167 HIS S C   1 
ATOM   5858 O O   . HIS D 4 167 ? 145.766 108.195 152.909 1.00 73.26  ?  167 HIS S O   1 
ATOM   5859 C CB  . HIS D 4 167 ? 142.814 107.379 151.403 1.00 73.26  ?  167 HIS S CB  1 
ATOM   5860 C CG  . HIS D 4 167 ? 142.752 107.571 149.920 1.00 73.26  ?  167 HIS S CG  1 
ATOM   5861 N ND1 . HIS D 4 167 ? 142.983 108.789 149.317 1.00 73.26  ?  167 HIS S ND1 1 
ATOM   5862 C CD2 . HIS D 4 167 ? 142.486 106.701 148.918 1.00 73.26  ?  167 HIS S CD2 1 
ATOM   5863 C CE1 . HIS D 4 167 ? 142.861 108.661 148.009 1.00 73.26  ?  167 HIS S CE1 1 
ATOM   5864 N NE2 . HIS D 4 167 ? 142.559 107.404 147.740 1.00 73.26  ?  167 HIS S NE2 1 
ATOM   5865 N N   . SER D 4 168 ? 145.647 108.164 150.657 1.00 76.15  ?  168 SER S N   1 
ATOM   5866 C CA  . SER D 4 168 ? 146.710 109.150 150.500 1.00 76.15  ?  168 SER S CA  1 
ATOM   5867 C C   . SER D 4 168 ? 146.310 110.525 151.019 1.00 76.15  ?  168 SER S C   1 
ATOM   5868 O O   . SER D 4 168 ? 147.189 111.346 151.298 1.00 76.15  ?  168 SER S O   1 
ATOM   5869 C CB  . SER D 4 168 ? 147.119 109.251 149.031 1.00 76.15  ?  168 SER S CB  1 
ATOM   5870 O OG  . SER D 4 168 ? 146.279 110.151 148.330 1.00 76.15  ?  168 SER S OG  1 
ATOM   5871 N N   . ASN D 4 169 ? 145.009 110.796 151.151 1.00 75.66  ?  169 ASN S N   1 
ATOM   5872 C CA  . ASN D 4 169 ? 144.562 112.070 151.699 1.00 75.66  ?  169 ASN S CA  1 
ATOM   5873 C C   . ASN D 4 169 ? 144.905 112.219 153.174 1.00 75.66  ?  169 ASN S C   1 
ATOM   5874 O O   . ASN D 4 169 ? 144.884 113.340 153.693 1.00 75.66  ?  169 ASN S O   1 
ATOM   5875 C CB  . ASN D 4 169 ? 143.052 112.229 151.514 1.00 75.66  ?  169 ASN S CB  1 
ATOM   5876 C CG  . ASN D 4 169 ? 142.603 111.930 150.101 1.00 75.66  ?  169 ASN S CG  1 
ATOM   5877 O OD1 . ASN D 4 169 ? 143.278 112.282 149.135 1.00 75.66  ?  169 ASN S OD1 1 
ATOM   5878 N ND2 . ASN D 4 169 ? 141.450 111.283 149.973 1.00 75.66  ?  169 ASN S ND2 1 
ATOM   5879 N N   . GLY D 4 170 ? 145.218 111.121 153.857 1.00 73.04  ?  170 GLY S N   1 
ATOM   5880 C CA  . GLY D 4 170 ? 145.419 111.115 155.284 1.00 73.04  ?  170 GLY S CA  1 
ATOM   5881 C C   . GLY D 4 170 ? 144.220 110.636 156.075 1.00 73.04  ?  170 GLY S C   1 
ATOM   5882 O O   . GLY D 4 170 ? 144.374 110.263 157.243 1.00 73.04  ?  170 GLY S O   1 
ATOM   5883 N N   . ASN D 4 171 ? 143.037 110.638 155.468 1.00 69.91  ?  171 ASN S N   1 
ATOM   5884 C CA  . ASN D 4 171 ? 141.844 110.120 156.120 1.00 69.91  ?  171 ASN S CA  1 
ATOM   5885 C C   . ASN D 4 171 ? 141.867 108.599 156.131 1.00 69.91  ?  171 ASN S C   1 
ATOM   5886 O O   . ASN D 4 171 ? 142.323 107.962 155.177 1.00 69.91  ?  171 ASN S O   1 
ATOM   5887 C CB  . ASN D 4 171 ? 140.586 110.615 155.407 1.00 69.91  ?  171 ASN S CB  1 
ATOM   5888 C CG  . ASN D 4 171 ? 140.539 112.122 155.288 1.00 69.91  ?  171 ASN S CG  1 
ATOM   5889 O OD1 . ASN D 4 171 ? 140.962 112.841 156.192 1.00 69.91  ?  171 ASN S OD1 1 
ATOM   5890 N ND2 . ASN D 4 171 ? 140.021 112.611 154.168 1.00 69.91  ?  171 ASN S ND2 1 
ATOM   5891 N N   . THR D 4 172 ? 141.373 108.019 157.218 1.00 67.96  ?  172 THR S N   1 
ATOM   5892 C CA  . THR D 4 172 ? 141.249 106.571 157.358 1.00 67.96  ?  172 THR S CA  1 
ATOM   5893 C C   . THR D 4 172 ? 139.760 106.253 157.421 1.00 67.96  ?  172 THR S C   1 
ATOM   5894 O O   . THR D 4 172 ? 139.136 106.360 158.480 1.00 67.96  ?  172 THR S O   1 
ATOM   5895 C CB  . THR D 4 172 ? 141.984 106.071 158.595 1.00 67.96  ?  172 THR S CB  1 
ATOM   5896 O OG1 . THR D 4 172 ? 143.270 106.697 158.672 1.00 67.96  ?  172 THR S OG1 1 
ATOM   5897 C CG2 . THR D 4 172 ? 142.171 104.571 158.517 1.00 67.96  ?  172 THR S CG2 1 
ATOM   5898 N N   . TYR D 4 173 ? 139.197 105.852 156.282 1.00 63.86  ?  173 TYR S N   1 
ATOM   5899 C CA  . TYR D 4 173 ? 137.750 105.719 156.128 1.00 63.86  ?  173 TYR S CA  1 
ATOM   5900 C C   . TYR D 4 173 ? 137.263 104.457 156.833 1.00 63.86  ?  173 TYR S C   1 
ATOM   5901 O O   . TYR D 4 173 ? 137.055 103.403 156.228 1.00 63.86  ?  173 TYR S O   1 
ATOM   5902 C CB  . TYR D 4 173 ? 137.377 105.705 154.651 1.00 63.86  ?  173 TYR S CB  1 
ATOM   5903 C CG  . TYR D 4 173 ? 137.835 106.930 153.897 1.00 63.86  ?  173 TYR S CG  1 
ATOM   5904 C CD1 . TYR D 4 173 ? 137.144 108.128 153.996 1.00 63.86  ?  173 TYR S CD1 1 
ATOM   5905 C CD2 . TYR D 4 173 ? 138.959 106.888 153.086 1.00 63.86  ?  173 TYR S CD2 1 
ATOM   5906 C CE1 . TYR D 4 173 ? 137.559 109.249 153.309 1.00 63.86  ?  173 TYR S CE1 1 
ATOM   5907 C CE2 . TYR D 4 173 ? 139.381 108.004 152.394 1.00 63.86  ?  173 TYR S CE2 1 
ATOM   5908 C CZ  . TYR D 4 173 ? 138.678 109.182 152.509 1.00 63.86  ?  173 TYR S CZ  1 
ATOM   5909 O OH  . TYR D 4 173 ? 139.095 110.297 151.822 1.00 63.86  ?  173 TYR S OH  1 
ATOM   5910 N N   . LEU D 4 174 ? 137.076 104.570 158.145 1.00 64.43  ?  174 LEU S N   1 
ATOM   5911 C CA  . LEU D 4 174 ? 136.419 103.532 158.925 1.00 64.43  ?  174 LEU S CA  1 
ATOM   5912 C C   . LEU D 4 174 ? 135.421 104.168 159.880 1.00 64.43  ?  174 LEU S C   1 
ATOM   5913 O O   . LEU D 4 174 ? 135.693 105.212 160.479 1.00 64.43  ?  174 LEU S O   1 
ATOM   5914 C CB  . LEU D 4 174 ? 137.426 102.666 159.694 1.00 64.43  ?  174 LEU S CB  1 
ATOM   5915 C CG  . LEU D 4 174 ? 136.798 101.514 160.484 1.00 64.43  ?  174 LEU S CG  1 
ATOM   5916 C CD1 . LEU D 4 174 ? 137.650 100.279 160.399 1.00 64.43  ?  174 LEU S CD1 1 
ATOM   5917 C CD2 . LEU D 4 174 ? 136.622 101.900 161.942 1.00 64.43  ?  174 LEU S CD2 1 
ATOM   5918 N N   . TYR D 4 175 ? 134.268 103.521 160.016 1.00 61.41  ?  175 TYR S N   1 
ATOM   5919 C CA  . TYR D 4 175 ? 133.147 104.022 160.794 1.00 61.41  ?  175 TYR S CA  1 
ATOM   5920 C C   . TYR D 4 175 ? 132.771 102.998 161.855 1.00 61.41  ?  175 TYR S C   1 
ATOM   5921 O O   . TYR D 4 175 ? 132.809 101.791 161.606 1.00 61.41  ?  175 TYR S O   1 
ATOM   5922 C CB  . TYR D 4 175 ? 131.937 104.308 159.895 1.00 61.41  ?  175 TYR S CB  1 
ATOM   5923 C CG  . TYR D 4 175 ? 132.131 105.448 158.918 1.00 61.41  ?  175 TYR S CG  1 
ATOM   5924 C CD1 . TYR D 4 175 ? 133.078 105.372 157.907 1.00 61.41  ?  175 TYR S CD1 1 
ATOM   5925 C CD2 . TYR D 4 175 ? 131.358 106.596 159.002 1.00 61.41  ?  175 TYR S CD2 1 
ATOM   5926 C CE1 . TYR D 4 175 ? 133.258 106.407 157.018 1.00 61.41  ?  175 TYR S CE1 1 
ATOM   5927 C CE2 . TYR D 4 175 ? 131.529 107.635 158.112 1.00 61.41  ?  175 TYR S CE2 1 
ATOM   5928 C CZ  . TYR D 4 175 ? 132.482 107.535 157.124 1.00 61.41  ?  175 TYR S CZ  1 
ATOM   5929 O OH  . TYR D 4 175 ? 132.659 108.568 156.237 1.00 61.41  ?  175 TYR S OH  1 
ATOM   5930 N N   . TRP D 4 176 ? 132.408 103.488 163.035 1.00 67.65  ?  176 TRP S N   1 
ATOM   5931 C CA  . TRP D 4 176 ? 131.953 102.658 164.143 1.00 67.65  ?  176 TRP S CA  1 
ATOM   5932 C C   . TRP D 4 176 ? 130.501 102.998 164.435 1.00 67.65  ?  176 TRP S C   1 
ATOM   5933 O O   . TRP D 4 176 ? 130.189 104.149 164.770 1.00 67.65  ?  176 TRP S O   1 
ATOM   5934 C CB  . TRP D 4 176 ? 132.809 102.877 165.392 1.00 67.65  ?  176 TRP S CB  1 
ATOM   5935 C CG  . TRP D 4 176 ? 134.104 102.139 165.378 1.00 67.65  ?  176 TRP S CG  1 
ATOM   5936 C CD1 . TRP D 4 176 ? 135.339 102.658 165.129 1.00 67.65  ?  176 TRP S CD1 1 
ATOM   5937 C CD2 . TRP D 4 176 ? 134.297 100.744 165.629 1.00 67.65  ?  176 TRP S CD2 1 
ATOM   5938 N NE1 . TRP D 4 176 ? 136.290 101.671 165.207 1.00 67.65  ?  176 TRP S NE1 1 
ATOM   5939 C CE2 . TRP D 4 176 ? 135.676 100.486 165.512 1.00 67.65  ?  176 TRP S CE2 1 
ATOM   5940 C CE3 . TRP D 4 176 ? 133.437 99.687  165.939 1.00 67.65  ?  176 TRP S CE3 1 
ATOM   5941 C CZ2 . TRP D 4 176 ? 136.214 99.216  165.695 1.00 67.65  ?  176 TRP S CZ2 1 
ATOM   5942 C CZ3 . TRP D 4 176 ? 133.974 98.428  166.119 1.00 67.65  ?  176 TRP S CZ3 1 
ATOM   5943 C CH2 . TRP D 4 176 ? 135.349 98.203  165.997 1.00 67.65  ?  176 TRP S CH2 1 
ATOM   5944 N N   . PHE D 4 177 ? 129.630 101.993 164.321 1.00 63.48  ?  177 PHE S N   1 
ATOM   5945 C CA  . PHE D 4 177 ? 128.204 102.101 164.589 1.00 63.48  ?  177 PHE S CA  1 
ATOM   5946 C C   . PHE D 4 177 ? 127.818 101.211 165.764 1.00 63.48  ?  177 PHE S C   1 
ATOM   5947 O O   . PHE D 4 177 ? 128.440 100.174 166.007 1.00 63.48  ?  177 PHE S O   1 
ATOM   5948 C CB  . PHE D 4 177 ? 127.366 101.685 163.375 1.00 63.48  ?  177 PHE S CB  1 
ATOM   5949 C CG  . PHE D 4 177 ? 127.670 102.450 162.124 1.00 63.48  ?  177 PHE S CG  1 
ATOM   5950 C CD1 . PHE D 4 177 ? 127.042 103.654 161.867 1.00 63.48  ?  177 PHE S CD1 1 
ATOM   5951 C CD2 . PHE D 4 177 ? 128.557 101.950 161.190 1.00 63.48  ?  177 PHE S CD2 1 
ATOM   5952 C CE1 . PHE D 4 177 ? 127.309 104.354 160.712 1.00 63.48  ?  177 PHE S CE1 1 
ATOM   5953 C CE2 . PHE D 4 177 ? 128.827 102.647 160.033 1.00 63.48  ?  177 PHE S CE2 1 
ATOM   5954 C CZ  . PHE D 4 177 ? 128.203 103.850 159.795 1.00 63.48  ?  177 PHE S CZ  1 
ATOM   5955 N N   . LEU D 4 178 ? 126.768 101.615 166.476 1.00 71.97  ?  178 LEU S N   1 
ATOM   5956 C CA  . LEU D 4 178 ? 126.160 100.809 167.527 1.00 71.97  ?  178 LEU S CA  1 
ATOM   5957 C C   . LEU D 4 178 ? 124.690 100.582 167.222 1.00 71.97  ?  178 LEU S C   1 
ATOM   5958 O O   . LEU D 4 178 ? 123.968 101.525 166.883 1.00 71.97  ?  178 LEU S O   1 
ATOM   5959 C CB  . LEU D 4 178 ? 126.301 101.465 168.901 1.00 71.97  ?  178 LEU S CB  1 
ATOM   5960 C CG  . LEU D 4 178 ? 125.736 100.658 170.071 1.00 71.97  ?  178 LEU S CG  1 
ATOM   5961 C CD1 . LEU D 4 178 ? 126.460 99.343  170.229 1.00 71.97  ?  178 LEU S CD1 1 
ATOM   5962 C CD2 . LEU D 4 178 ? 125.806 101.460 171.358 1.00 71.97  ?  178 LEU S CD2 1 
ATOM   5963 N N   . GLN D 4 179 ? 124.251 99.335  167.354 1.00 75.30  ?  179 GLN S N   1 
ATOM   5964 C CA  . GLN D 4 179 ? 122.844 98.970  167.266 1.00 75.30  ?  179 GLN S CA  1 
ATOM   5965 C C   . GLN D 4 179 ? 122.414 98.465  168.637 1.00 75.30  ?  179 GLN S C   1 
ATOM   5966 O O   . GLN D 4 179 ? 122.877 97.413  169.090 1.00 75.30  ?  179 GLN S O   1 
ATOM   5967 C CB  . GLN D 4 179 ? 122.615 97.913  166.189 1.00 75.30  ?  179 GLN S CB  1 
ATOM   5968 C CG  . GLN D 4 179 ? 121.209 97.345  166.172 1.00 75.30  ?  179 GLN S CG  1 
ATOM   5969 C CD  . GLN D 4 179 ? 120.844 96.744  164.832 1.00 75.30  ?  179 GLN S CD  1 
ATOM   5970 O OE1 . GLN D 4 179 ? 121.557 95.888  164.310 1.00 75.30  ?  179 GLN S OE1 1 
ATOM   5971 N NE2 . GLN D 4 179 ? 119.732 97.193  164.266 1.00 75.30  ?  179 GLN S NE2 1 
ATOM   5972 N N   . ARG D 4 180 ? 121.558 99.232  169.302 1.00 82.10  ?  180 ARG S N   1 
ATOM   5973 C CA  . ARG D 4 180 ? 120.994 98.831  170.577 1.00 82.10  ?  180 ARG S CA  1 
ATOM   5974 C C   . ARG D 4 180 ? 119.891 97.801  170.359 1.00 82.10  ?  180 ARG S C   1 
ATOM   5975 O O   . ARG D 4 180 ? 119.324 97.710  169.267 1.00 82.10  ?  180 ARG S O   1 
ATOM   5976 C CB  . ARG D 4 180 ? 120.452 100.051 171.316 1.00 82.10  ?  180 ARG S CB  1 
ATOM   5977 C CG  . ARG D 4 180 ? 121.528 101.024 171.769 1.00 82.10  ?  180 ARG S CG  1 
ATOM   5978 C CD  . ARG D 4 180 ? 120.927 102.256 172.424 1.00 82.10  ?  180 ARG S CD  1 
ATOM   5979 N NE  . ARG D 4 180 ? 121.951 103.213 172.824 1.00 82.10  ?  180 ARG S NE  1 
ATOM   5980 C CZ  . ARG D 4 180 ? 122.440 104.159 172.034 1.00 82.10  ?  180 ARG S CZ  1 
ATOM   5981 N NH1 . ARG D 4 180 ? 122.021 104.305 170.788 1.00 82.10  1  180 ARG S NH1 1 
ATOM   5982 N NH2 . ARG D 4 180 ? 123.374 104.980 172.507 1.00 82.10  ?  180 ARG S NH2 1 
ATOM   5983 N N   . PRO D 4 181 ? 119.583 96.995  171.376 1.00 84.58  ?  181 PRO S N   1 
ATOM   5984 C CA  . PRO D 4 181 ? 118.517 95.996  171.222 1.00 84.58  ?  181 PRO S CA  1 
ATOM   5985 C C   . PRO D 4 181 ? 117.196 96.644  170.834 1.00 84.58  ?  181 PRO S C   1 
ATOM   5986 O O   . PRO D 4 181 ? 116.727 97.581  171.484 1.00 84.58  ?  181 PRO S O   1 
ATOM   5987 C CB  . PRO D 4 181 ? 118.443 95.344  172.607 1.00 84.58  ?  181 PRO S CB  1 
ATOM   5988 C CG  . PRO D 4 181 ? 119.802 95.535  173.179 1.00 84.58  ?  181 PRO S CG  1 
ATOM   5989 C CD  . PRO D 4 181 ? 120.284 96.860  172.665 1.00 84.58  ?  181 PRO S CD  1 
ATOM   5990 N N   . GLY D 4 182 ? 116.598 96.131  169.764 1.00 84.82  ?  182 GLY S N   1 
ATOM   5991 C CA  . GLY D 4 182 ? 115.345 96.677  169.266 1.00 84.82  ?  182 GLY S CA  1 
ATOM   5992 C C   . GLY D 4 182 ? 115.444 98.113  168.800 1.00 84.82  ?  182 GLY S C   1 
ATOM   5993 O O   . GLY D 4 182 ? 114.510 98.897  169.011 1.00 84.82  ?  182 GLY S O   1 
ATOM   5994 N N   . GLN D 4 183 ? 116.554 98.477  168.162 1.00 80.78  ?  183 GLN S N   1 
ATOM   5995 C CA  . GLN D 4 183 ? 116.756 99.841  167.698 1.00 80.78  ?  183 GLN S CA  1 
ATOM   5996 C C   . GLN D 4 183 ? 117.583 99.823  166.422 1.00 80.78  ?  183 GLN S C   1 
ATOM   5997 O O   . GLN D 4 183 ? 118.248 98.835  166.100 1.00 80.78  ?  183 GLN S O   1 
ATOM   5998 C CB  . GLN D 4 183 ? 117.442 100.707 168.761 1.00 80.78  ?  183 GLN S CB  1 
ATOM   5999 C CG  . GLN D 4 183 ? 116.497 101.302 169.789 1.00 80.78  ?  183 GLN S CG  1 
ATOM   6000 C CD  . GLN D 4 183 ? 117.180 102.314 170.687 1.00 80.78  ?  183 GLN S CD  1 
ATOM   6001 O OE1 . GLN D 4 183 ? 117.844 103.234 170.211 1.00 80.78  ?  183 GLN S OE1 1 
ATOM   6002 N NE2 . GLN D 4 183 ? 117.020 102.147 171.994 1.00 80.78  ?  183 GLN S NE2 1 
ATOM   6003 N N   . SER D 4 184 ? 117.528 100.934 165.695 1.00 69.90  ?  184 SER S N   1 
ATOM   6004 C CA  . SER D 4 184 ? 118.309 101.094 164.481 1.00 69.90  ?  184 SER S CA  1 
ATOM   6005 C C   . SER D 4 184 ? 119.760 101.430 164.820 1.00 69.90  ?  184 SER S C   1 
ATOM   6006 O O   . SER D 4 184 ? 120.045 101.967 165.894 1.00 69.90  ?  184 SER S O   1 
ATOM   6007 C CB  . SER D 4 184 ? 117.717 102.197 163.613 1.00 69.90  ?  184 SER S CB  1 
ATOM   6008 O OG  . SER D 4 184 ? 117.860 103.462 164.233 1.00 69.90  ?  184 SER S OG  1 
ATOM   6009 N N   . PRO D 4 185 ? 120.696 101.110 163.926 1.00 64.46  ?  185 PRO S N   1 
ATOM   6010 C CA  . PRO D 4 185 ? 122.098 101.464 164.175 1.00 64.46  ?  185 PRO S CA  1 
ATOM   6011 C C   . PRO D 4 185 ? 122.286 102.968 164.292 1.00 64.46  ?  185 PRO S C   1 
ATOM   6012 O O   . PRO D 4 185 ? 121.622 103.758 163.618 1.00 64.46  ?  185 PRO S O   1 
ATOM   6013 C CB  . PRO D 4 185 ? 122.828 100.903 162.949 1.00 64.46  ?  185 PRO S CB  1 
ATOM   6014 C CG  . PRO D 4 185 ? 121.942 99.817  162.452 1.00 64.46  ?  185 PRO S CG  1 
ATOM   6015 C CD  . PRO D 4 185 ? 120.544 100.288 162.714 1.00 64.46  ?  185 PRO S CD  1 
ATOM   6016 N N   . GLN D 4 186 ? 123.206 103.358 165.169 1.00 68.35  ?  186 GLN S N   1 
ATOM   6017 C CA  . GLN D 4 186 ? 123.525 104.755 165.422 1.00 68.35  ?  186 GLN S CA  1 
ATOM   6018 C C   . GLN D 4 186 ? 124.999 104.985 165.128 1.00 68.35  ?  186 GLN S C   1 
ATOM   6019 O O   . GLN D 4 186 ? 125.839 104.146 165.467 1.00 68.35  ?  186 GLN S O   1 
ATOM   6020 C CB  . GLN D 4 186 ? 123.203 105.138 166.869 1.00 68.35  ?  186 GLN S CB  1 
ATOM   6021 C CG  . GLN D 4 186 ? 123.657 106.532 167.265 1.00 68.35  ?  186 GLN S CG  1 
ATOM   6022 C CD  . GLN D 4 186 ? 123.669 106.734 168.767 1.00 68.35  ?  186 GLN S CD  1 
ATOM   6023 O OE1 . GLN D 4 186 ? 122.955 106.053 169.502 1.00 68.35  ?  186 GLN S OE1 1 
ATOM   6024 N NE2 . GLN D 4 186 ? 124.487 107.672 169.231 1.00 68.35  ?  186 GLN S NE2 1 
ATOM   6025 N N   . LEU D 4 187 ? 125.309 106.107 164.485 1.00 63.26  ?  187 LEU S N   1 
ATOM   6026 C CA  . LEU D 4 187 ? 126.696 106.438 164.193 1.00 63.26  ?  187 LEU S CA  1 
ATOM   6027 C C   . LEU D 4 187 ? 127.400 106.931 165.449 1.00 63.26  ?  187 LEU S C   1 
ATOM   6028 O O   . LEU D 4 187 ? 126.888 107.798 166.163 1.00 63.26  ?  187 LEU S O   1 
ATOM   6029 C CB  . LEU D 4 187 ? 126.771 107.500 163.099 1.00 63.26  ?  187 LEU S CB  1 
ATOM   6030 C CG  . LEU D 4 187 ? 128.162 108.070 162.815 1.00 63.26  ?  187 LEU S CG  1 
ATOM   6031 C CD1 . LEU D 4 187 ? 129.072 107.009 162.227 1.00 63.26  ?  187 LEU S CD1 1 
ATOM   6032 C CD2 . LEU D 4 187 ? 128.069 109.268 161.891 1.00 63.26  ?  187 LEU S CD2 1 
ATOM   6033 N N   . LEU D 4 188 ? 128.578 106.375 165.719 1.00 68.90  ?  188 LEU S N   1 
ATOM   6034 C CA  . LEU D 4 188 ? 129.424 106.809 166.823 1.00 68.90  ?  188 LEU S CA  1 
ATOM   6035 C C   . LEU D 4 188 ? 130.725 107.437 166.355 1.00 68.90  ?  188 LEU S C   1 
ATOM   6036 O O   . LEU D 4 188 ? 131.069 108.540 166.787 1.00 68.90  ?  188 LEU S O   1 
ATOM   6037 C CB  . LEU D 4 188 ? 129.728 105.637 167.766 1.00 68.90  ?  188 LEU S CB  1 
ATOM   6038 C CG  . LEU D 4 188 ? 128.653 105.252 168.783 1.00 68.90  ?  188 LEU S CG  1 
ATOM   6039 C CD1 . LEU D 4 188 ? 127.462 104.618 168.117 1.00 68.90  ?  188 LEU S CD1 1 
ATOM   6040 C CD2 . LEU D 4 188 ? 129.240 104.309 169.814 1.00 68.90  ?  188 LEU S CD2 1 
ATOM   6041 N N   . ILE D 4 189 ? 131.464 106.764 165.479 1.00 65.97  ?  189 ILE S N   1 
ATOM   6042 C CA  . ILE D 4 189 ? 132.759 107.255 165.024 1.00 65.97  ?  189 ILE S CA  1 
ATOM   6043 C C   . ILE D 4 189 ? 132.768 107.284 163.505 1.00 65.97  ?  189 ILE S C   1 
ATOM   6044 O O   . ILE D 4 189 ? 132.332 106.327 162.860 1.00 65.97  ?  189 ILE S O   1 
ATOM   6045 C CB  . ILE D 4 189 ? 133.916 106.383 165.558 1.00 65.97  ?  189 ILE S CB  1 
ATOM   6046 C CG1 . ILE D 4 189 ? 133.960 106.430 167.086 1.00 65.97  ?  189 ILE S CG1 1 
ATOM   6047 C CG2 . ILE D 4 189 ? 135.244 106.832 164.974 1.00 65.97  ?  189 ILE S CG2 1 
ATOM   6048 C CD1 . ILE D 4 189 ? 134.525 107.714 167.640 1.00 65.97  ?  189 ILE S CD1 1 
ATOM   6049 N N   . TYR D 4 190 ? 133.254 108.380 162.929 1.00 63.36  ?  190 TYR S N   1 
ATOM   6050 C CA  . TYR D 4 190 ? 133.455 108.467 161.489 1.00 63.36  ?  190 TYR S CA  1 
ATOM   6051 C C   . TYR D 4 190 ? 134.906 108.822 161.202 1.00 63.36  ?  190 TYR S C   1 
ATOM   6052 O O   . TYR D 4 190 ? 135.473 109.709 161.848 1.00 63.36  ?  190 TYR S O   1 
ATOM   6053 C CB  . TYR D 4 190 ? 132.501 109.479 160.842 1.00 63.36  ?  190 TYR S CB  1 
ATOM   6054 C CG  . TYR D 4 190 ? 132.600 110.903 161.334 1.00 63.36  ?  190 TYR S CG  1 
ATOM   6055 C CD1 . TYR D 4 190 ? 131.956 111.306 162.494 1.00 63.36  ?  190 TYR S CD1 1 
ATOM   6056 C CD2 . TYR D 4 190 ? 133.300 111.858 160.610 1.00 63.36  ?  190 TYR S CD2 1 
ATOM   6057 C CE1 . TYR D 4 190 ? 132.031 112.611 162.936 1.00 63.36  ?  190 TYR S CE1 1 
ATOM   6058 C CE2 . TYR D 4 190 ? 133.379 113.165 161.042 1.00 63.36  ?  190 TYR S CE2 1 
ATOM   6059 C CZ  . TYR D 4 190 ? 132.742 113.537 162.205 1.00 63.36  ?  190 TYR S CZ  1 
ATOM   6060 O OH  . TYR D 4 190 ? 132.821 114.839 162.641 1.00 63.36  ?  190 TYR S OH  1 
ATOM   6061 N N   . ARG D 4 191 ? 135.501 108.110 160.241 1.00 63.31  ?  191 ARG S N   1 
ATOM   6062 C CA  . ARG D 4 191 ? 136.901 108.285 159.849 1.00 63.31  ?  191 ARG S CA  1 
ATOM   6063 C C   . ARG D 4 191 ? 137.856 107.995 161.008 1.00 63.31  ?  191 ARG S C   1 
ATOM   6064 O O   . ARG D 4 191 ? 138.922 108.602 161.125 1.00 63.31  ?  191 ARG S O   1 
ATOM   6065 C CB  . ARG D 4 191 ? 137.144 109.678 159.264 1.00 63.31  ?  191 ARG S CB  1 
ATOM   6066 C CG  . ARG D 4 191 ? 136.832 109.763 157.778 1.00 63.31  ?  191 ARG S CG  1 
ATOM   6067 C CD  . ARG D 4 191 ? 137.171 111.126 157.209 1.00 63.31  ?  191 ARG S CD  1 
ATOM   6068 N NE  . ARG D 4 191 ? 136.349 112.177 157.795 1.00 63.31  ?  191 ARG S NE  1 
ATOM   6069 C CZ  . ARG D 4 191 ? 135.185 112.575 157.303 1.00 63.31  ?  191 ARG S CZ  1 
ATOM   6070 N NH1 . ARG D 4 191 ? 134.672 112.029 156.213 1.00 63.31  1  191 ARG S NH1 1 
ATOM   6071 N NH2 . ARG D 4 191 ? 134.518 113.546 157.920 1.00 63.31  ?  191 ARG S NH2 1 
ATOM   6072 N N   . MET D 4 192 ? 137.443 107.079 161.887 1.00 72.26  ?  192 MET S N   1 
ATOM   6073 C CA  . MET D 4 192 ? 138.311 106.386 162.838 1.00 72.26  ?  192 MET S CA  1 
ATOM   6074 C C   . MET D 4 192 ? 138.774 107.276 163.991 1.00 72.26  ?  192 MET S C   1 
ATOM   6075 O O   . MET D 4 192 ? 139.269 106.774 165.005 1.00 72.26  ?  192 MET S O   1 
ATOM   6076 C CB  . MET D 4 192 ? 139.518 105.801 162.086 1.00 72.26  ?  192 MET S CB  1 
ATOM   6077 C CG  . MET D 4 192 ? 140.673 105.303 162.945 1.00 72.26  ?  192 MET S CG  1 
ATOM   6078 S SD  . MET D 4 192 ? 142.254 105.295 162.084 1.00 72.26  ?  192 MET S SD  1 
ATOM   6079 C CE  . MET D 4 192 ? 142.968 106.825 162.679 1.00 72.26  ?  192 MET S CE  1 
ATOM   6080 N N   . SER D 4 193 ? 138.551 108.584 163.899 1.00 69.75  ?  193 SER S N   1 
ATOM   6081 C CA  . SER D 4 193 ? 139.062 109.469 164.939 1.00 69.75  ?  193 SER S CA  1 
ATOM   6082 C C   . SER D 4 193 ? 138.007 110.454 165.418 1.00 69.75  ?  193 SER S C   1 
ATOM   6083 O O   . SER D 4 193 ? 138.046 110.905 166.566 1.00 69.75  ?  193 SER S O   1 
ATOM   6084 C CB  . SER D 4 193 ? 140.292 110.226 164.433 1.00 69.75  ?  193 SER S CB  1 
ATOM   6085 O OG  . SER D 4 193 ? 141.368 109.341 164.181 1.00 69.75  ?  193 SER S OG  1 
ATOM   6086 N N   . ASN D 4 194 ? 137.060 110.787 164.550 1.00 67.03  ?  194 ASN S N   1 
ATOM   6087 C CA  . ASN D 4 194 ? 136.082 111.821 164.843 1.00 67.03  ?  194 ASN S CA  1 
ATOM   6088 C C   . ASN D 4 194 ? 134.867 111.228 165.540 1.00 67.03  ?  194 ASN S C   1 
ATOM   6089 O O   . ASN D 4 194 ? 134.402 110.140 165.191 1.00 67.03  ?  194 ASN S O   1 
ATOM   6090 C CB  . ASN D 4 194 ? 135.660 112.532 163.559 1.00 67.03  ?  194 ASN S CB  1 
ATOM   6091 C CG  . ASN D 4 194 ? 136.839 112.886 162.679 1.00 67.03  ?  194 ASN S CG  1 
ATOM   6092 O OD1 . ASN D 4 194 ? 137.235 112.110 161.810 1.00 67.03  ?  194 ASN S OD1 1 
ATOM   6093 N ND2 . ASN D 4 194 ? 137.409 114.064 162.900 1.00 67.03  ?  194 ASN S ND2 1 
ATOM   6094 N N   . LEU D 4 195 ? 134.359 111.954 166.531 1.00 72.53  ?  195 LEU S N   1 
ATOM   6095 C CA  . LEU D 4 195 ? 133.198 111.525 167.297 1.00 72.53  ?  195 LEU S CA  1 
ATOM   6096 C C   . LEU D 4 195 ? 131.940 112.158 166.718 1.00 72.53  ?  195 LEU S C   1 
ATOM   6097 O O   . LEU D 4 195 ? 131.894 113.372 166.496 1.00 72.53  ?  195 LEU S O   1 
ATOM   6098 C CB  . LEU D 4 195 ? 133.359 111.906 168.768 1.00 72.53  ?  195 LEU S CB  1 
ATOM   6099 C CG  . LEU D 4 195 ? 132.405 111.243 169.760 1.00 72.53  ?  195 LEU S CG  1 
ATOM   6100 C CD1 . LEU D 4 195 ? 132.922 109.875 170.160 1.00 72.53  ?  195 LEU S CD1 1 
ATOM   6101 C CD2 . LEU D 4 195 ? 132.224 112.125 170.981 1.00 72.53  ?  195 LEU S CD2 1 
ATOM   6102 N N   . ALA D 4 196 ? 130.927 111.332 166.472 1.00 74.27  ?  196 ALA S N   1 
ATOM   6103 C CA  . ALA D 4 196 ? 129.691 111.815 165.875 1.00 74.27  ?  196 ALA S CA  1 
ATOM   6104 C C   . ALA D 4 196 ? 128.954 112.747 166.830 1.00 74.27  ?  196 ALA S C   1 
ATOM   6105 O O   . ALA D 4 196 ? 129.098 112.665 168.053 1.00 74.27  ?  196 ALA S O   1 
ATOM   6106 C CB  . ALA D 4 196 ? 128.790 110.643 165.491 1.00 74.27  ?  196 ALA S CB  1 
ATOM   6107 N N   . SER D 4 197 ? 128.164 113.650 166.253 1.00 79.37  ?  197 SER S N   1 
ATOM   6108 C CA  . SER D 4 197 ? 127.408 114.608 167.049 1.00 79.37  ?  197 SER S CA  1 
ATOM   6109 C C   . SER D 4 197 ? 126.395 113.891 167.932 1.00 79.37  ?  197 SER S C   1 
ATOM   6110 O O   . SER D 4 197 ? 125.692 112.982 167.482 1.00 79.37  ?  197 SER S O   1 
ATOM   6111 C CB  . SER D 4 197 ? 126.702 115.608 166.135 1.00 79.37  ?  197 SER S CB  1 
ATOM   6112 O OG  . SER D 4 197 ? 125.842 116.456 166.875 1.00 79.37  ?  197 SER S OG  1 
ATOM   6113 N N   . GLY D 4 198 ? 126.322 114.306 169.195 1.00 80.89  ?  198 GLY S N   1 
ATOM   6114 C CA  . GLY D 4 198 ? 125.427 113.703 170.156 1.00 80.89  ?  198 GLY S CA  1 
ATOM   6115 C C   . GLY D 4 198 ? 125.977 112.486 170.867 1.00 80.89  ?  198 GLY S C   1 
ATOM   6116 O O   . GLY D 4 198 ? 125.313 111.965 171.772 1.00 80.89  ?  198 GLY S O   1 
ATOM   6117 N N   . VAL D 4 199 ? 127.158 112.019 170.490 1.00 81.34  ?  199 VAL S N   1 
ATOM   6118 C CA  . VAL D 4 199 ? 127.760 110.851 171.135 1.00 81.34  ?  199 VAL S CA  1 
ATOM   6119 C C   . VAL D 4 199 ? 128.521 111.312 172.375 1.00 81.34  ?  199 VAL S C   1 
ATOM   6120 O O   . VAL D 4 199 ? 129.266 112.302 172.299 1.00 81.34  ?  199 VAL S O   1 
ATOM   6121 C CB  . VAL D 4 199 ? 128.681 110.119 170.164 1.00 81.34  ?  199 VAL S CB  1 
ATOM   6122 C CG1 . VAL D 4 199 ? 129.364 108.949 170.852 1.00 81.34  ?  199 VAL S CG1 1 
ATOM   6123 C CG2 . VAL D 4 199 ? 127.896 109.641 168.955 1.00 81.34  ?  199 VAL S CG2 1 
ATOM   6124 N N   . PRO D 4 200 ? 128.354 110.649 173.519 1.00 88.65  ?  200 PRO S N   1 
ATOM   6125 C CA  . PRO D 4 200 ? 129.136 111.019 174.703 1.00 88.65  ?  200 PRO S CA  1 
ATOM   6126 C C   . PRO D 4 200 ? 130.625 110.812 174.472 1.00 88.65  ?  200 PRO S C   1 
ATOM   6127 O O   . PRO D 4 200 ? 131.044 109.951 173.695 1.00 88.65  ?  200 PRO S O   1 
ATOM   6128 C CB  . PRO D 4 200 ? 128.601 110.083 175.793 1.00 88.65  ?  200 PRO S CB  1 
ATOM   6129 C CG  . PRO D 4 200 ? 127.927 108.971 175.056 1.00 88.65  ?  200 PRO S CG  1 
ATOM   6130 C CD  . PRO D 4 200 ? 127.384 109.581 173.806 1.00 88.65  ?  200 PRO S CD  1 
ATOM   6131 N N   . ASP D 4 201 ? 131.428 111.621 175.164 1.00 94.22  ?  201 ASP S N   1 
ATOM   6132 C CA  . ASP D 4 201 ? 132.872 111.633 174.959 1.00 94.22  ?  201 ASP S CA  1 
ATOM   6133 C C   . ASP D 4 201 ? 133.561 110.359 175.431 1.00 94.22  ?  201 ASP S C   1 
ATOM   6134 O O   . ASP D 4 201 ? 134.745 110.176 175.130 1.00 94.22  ?  201 ASP S O   1 
ATOM   6135 C CB  . ASP D 4 201 ? 133.488 112.840 175.668 1.00 94.22  ?  201 ASP S CB  1 
ATOM   6136 C CG  . ASP D 4 201 ? 132.867 114.151 175.232 1.00 94.22  ?  201 ASP S CG  1 
ATOM   6137 O OD1 . ASP D 4 201 ? 132.726 114.366 174.010 1.00 94.22  ?  201 ASP S OD1 1 
ATOM   6138 O OD2 . ASP D 4 201 ? 132.518 114.968 176.111 1.00 94.22  -1 201 ASP S OD2 1 
ATOM   6139 N N   . ARG D 4 202 ? 132.866 109.484 176.161 1.00 95.42  ?  202 ARG S N   1 
ATOM   6140 C CA  . ARG D 4 202 ? 133.497 108.265 176.655 1.00 95.42  ?  202 ARG S CA  1 
ATOM   6141 C C   . ARG D 4 202 ? 133.910 107.322 175.532 1.00 95.42  ?  202 ARG S C   1 
ATOM   6142 O O   . ARG D 4 202 ? 134.786 106.477 175.742 1.00 95.42  ?  202 ARG S O   1 
ATOM   6143 C CB  . ARG D 4 202 ? 132.565 107.543 177.630 1.00 95.42  ?  202 ARG S CB  1 
ATOM   6144 C CG  . ARG D 4 202 ? 131.185 107.240 177.076 1.00 95.42  ?  202 ARG S CG  1 
ATOM   6145 C CD  . ARG D 4 202 ? 130.459 106.233 177.955 1.00 95.42  ?  202 ARG S CD  1 
ATOM   6146 N NE  . ARG D 4 202 ? 129.055 106.086 177.590 1.00 95.42  ?  202 ARG S NE  1 
ATOM   6147 C CZ  . ARG D 4 202 ? 128.106 106.960 177.894 1.00 95.42  ?  202 ARG S CZ  1 
ATOM   6148 N NH1 . ARG D 4 202 ? 128.372 108.061 178.578 1.00 95.42  1  202 ARG S NH1 1 
ATOM   6149 N NH2 . ARG D 4 202 ? 126.857 106.723 177.503 1.00 95.42  ?  202 ARG S NH2 1 
ATOM   6150 N N   . PHE D 4 203 ? 133.305 107.441 174.353 1.00 88.78  ?  203 PHE S N   1 
ATOM   6151 C CA  . PHE D 4 203 ? 133.718 106.645 173.206 1.00 88.78  ?  203 PHE S CA  1 
ATOM   6152 C C   . PHE D 4 203 ? 134.908 107.297 172.516 1.00 88.78  ?  203 PHE S C   1 
ATOM   6153 O O   . PHE D 4 203 ? 134.953 108.519 172.352 1.00 88.78  ?  203 PHE S O   1 
ATOM   6154 C CB  . PHE D 4 203 ? 132.565 106.491 172.214 1.00 88.78  ?  203 PHE S CB  1 
ATOM   6155 C CG  . PHE D 4 203 ? 131.366 105.788 172.778 1.00 88.78  ?  203 PHE S CG  1 
ATOM   6156 C CD1 . PHE D 4 203 ? 131.261 104.410 172.714 1.00 88.78  ?  203 PHE S CD1 1 
ATOM   6157 C CD2 . PHE D 4 203 ? 130.337 106.506 173.362 1.00 88.78  ?  203 PHE S CD2 1 
ATOM   6158 C CE1 . PHE D 4 203 ? 130.157 103.761 173.228 1.00 88.78  ?  203 PHE S CE1 1 
ATOM   6159 C CE2 . PHE D 4 203 ? 129.230 105.862 173.878 1.00 88.78  ?  203 PHE S CE2 1 
ATOM   6160 C CZ  . PHE D 4 203 ? 129.140 104.488 173.811 1.00 88.78  ?  203 PHE S CZ  1 
ATOM   6161 N N   . SER D 4 204 ? 135.877 106.479 172.113 1.00 86.77  ?  204 SER S N   1 
ATOM   6162 C CA  . SER D 4 204 ? 137.045 107.000 171.408 1.00 86.77  ?  204 SER S CA  1 
ATOM   6163 C C   . SER D 4 204 ? 137.547 105.955 170.426 1.00 86.77  ?  204 SER S C   1 
ATOM   6164 O O   . SER D 4 204 ? 137.884 104.840 170.828 1.00 86.77  ?  204 SER S O   1 
ATOM   6165 C CB  . SER D 4 204 ? 138.151 107.387 172.392 1.00 86.77  ?  204 SER S CB  1 
ATOM   6166 O OG  . SER D 4 204 ? 138.668 106.245 173.051 1.00 86.77  ?  204 SER S OG  1 
ATOM   6167 N N   . GLY D 4 205 ? 137.609 106.314 169.149 1.00 82.02  ?  205 GLY S N   1 
ATOM   6168 C CA  . GLY D 4 205 ? 138.133 105.430 168.121 1.00 82.02  ?  205 GLY S CA  1 
ATOM   6169 C C   . GLY D 4 205 ? 139.582 105.765 167.816 1.00 82.02  ?  205 GLY S C   1 
ATOM   6170 O O   . GLY D 4 205 ? 139.969 106.934 167.799 1.00 82.02  ?  205 GLY S O   1 
ATOM   6171 N N   . SER D 4 206 ? 140.378 104.728 167.575 1.00 82.64  ?  206 SER S N   1 
ATOM   6172 C CA  . SER D 4 206 ? 141.794 104.912 167.284 1.00 82.64  ?  206 SER S CA  1 
ATOM   6173 C C   . SER D 4 206 ? 142.291 103.704 166.501 1.00 82.64  ?  206 SER S C   1 
ATOM   6174 O O   . SER D 4 206 ? 141.536 102.775 166.203 1.00 82.64  ?  206 SER S O   1 
ATOM   6175 C CB  . SER D 4 206 ? 142.600 105.120 168.569 1.00 82.64  ?  206 SER S CB  1 
ATOM   6176 O OG  . SER D 4 206 ? 142.299 104.120 169.526 1.00 82.64  ?  206 SER S OG  1 
ATOM   6177 N N   . GLY D 4 207 ? 143.573 103.726 166.169 1.00 83.35  ?  207 GLY S N   1 
ATOM   6178 C CA  . GLY D 4 207 ? 144.214 102.645 165.454 1.00 83.35  ?  207 GLY S CA  1 
ATOM   6179 C C   . GLY D 4 207 ? 144.866 103.124 164.172 1.00 83.35  ?  207 GLY S C   1 
ATOM   6180 O O   . GLY D 4 207 ? 144.832 104.302 163.821 1.00 83.35  ?  207 GLY S O   1 
ATOM   6181 N N   . SER D 4 208 ? 145.469 102.169 163.472 1.00 85.45  ?  208 SER S N   1 
ATOM   6182 C CA  . SER D 4 208 ? 146.128 102.413 162.199 1.00 85.45  ?  208 SER S CA  1 
ATOM   6183 C C   . SER D 4 208 ? 145.553 101.456 161.165 1.00 85.45  ?  208 SER S C   1 
ATOM   6184 O O   . SER D 4 208 ? 144.730 100.591 161.481 1.00 85.45  ?  208 SER S O   1 
ATOM   6185 C CB  . SER D 4 208 ? 147.648 102.249 162.318 1.00 85.45  ?  208 SER S CB  1 
ATOM   6186 O OG  . SER D 4 208 ? 148.010 100.879 162.347 1.00 85.45  ?  208 SER S OG  1 
ATOM   6187 N N   . GLY D 4 209 ? 145.987 101.614 159.918 1.00 84.49  ?  209 GLY S N   1 
ATOM   6188 C CA  . GLY D 4 209 ? 145.524 100.747 158.853 1.00 84.49  ?  209 GLY S CA  1 
ATOM   6189 C C   . GLY D 4 209 ? 145.699 99.281  159.192 1.00 84.49  ?  209 GLY S C   1 
ATOM   6190 O O   . GLY D 4 209 ? 146.761 98.877  159.674 1.00 84.49  ?  209 GLY S O   1 
ATOM   6191 N N   . THR D 4 210 ? 144.645 98.492  158.977 1.00 84.77  ?  210 THR S N   1 
ATOM   6192 C CA  . THR D 4 210 ? 144.536 97.055  159.201 1.00 84.77  ?  210 THR S CA  1 
ATOM   6193 C C   . THR D 4 210 ? 144.335 96.721  160.688 1.00 84.77  ?  210 THR S C   1 
ATOM   6194 O O   . THR D 4 210 ? 144.137 95.551  161.017 1.00 84.77  ?  210 THR S O   1 
ATOM   6195 C CB  . THR D 4 210 ? 145.745 96.265  158.653 1.00 84.77  ?  210 THR S CB  1 
ATOM   6196 O OG1 . THR D 4 210 ? 146.113 96.797  157.375 1.00 84.77  ?  210 THR S OG1 1 
ATOM   6197 C CG2 . THR D 4 210 ? 145.415 94.789  158.465 1.00 84.77  ?  210 THR S CG2 1 
ATOM   6198 N N   . ALA D 4 211 ? 144.340 97.700  161.593 1.00 83.24  ?  211 ALA S N   1 
ATOM   6199 C CA  . ALA D 4 211 ? 144.152 97.405  163.014 1.00 83.24  ?  211 ALA S CA  1 
ATOM   6200 C C   . ALA D 4 211 ? 143.487 98.599  163.684 1.00 83.24  ?  211 ALA S C   1 
ATOM   6201 O O   . ALA D 4 211 ? 144.135 99.626  163.905 1.00 83.24  ?  211 ALA S O   1 
ATOM   6202 C CB  . ALA D 4 211 ? 145.482 97.073  163.685 1.00 83.24  ?  211 ALA S CB  1 
ATOM   6203 N N   . PHE D 4 212 ? 142.217 98.448  164.055 1.00 79.81  ?  212 PHE S N   1 
ATOM   6204 C CA  . PHE D 4 212 ? 141.411 99.550  164.550 1.00 79.81  ?  212 PHE S CA  1 
ATOM   6205 C C   . PHE D 4 212 ? 140.751 99.139  165.857 1.00 79.81  ?  212 PHE S C   1 
ATOM   6206 O O   . PHE D 4 212 ? 140.451 97.963  166.077 1.00 79.81  ?  212 PHE S O   1 
ATOM   6207 C CB  . PHE D 4 212 ? 140.356 99.935  163.512 1.00 79.81  ?  212 PHE S CB  1 
ATOM   6208 C CG  . PHE D 4 212 ? 140.940 100.419 162.220 1.00 79.81  ?  212 PHE S CG  1 
ATOM   6209 C CD1 . PHE D 4 212 ? 141.573 101.644 162.144 1.00 79.81  ?  212 PHE S CD1 1 
ATOM   6210 C CD2 . PHE D 4 212 ? 140.842 99.649  161.076 1.00 79.81  ?  212 PHE S CD2 1 
ATOM   6211 C CE1 . PHE D 4 212 ? 142.103 102.086 160.952 1.00 79.81  ?  212 PHE S CE1 1 
ATOM   6212 C CE2 . PHE D 4 212 ? 141.371 100.086 159.883 1.00 79.81  ?  212 PHE S CE2 1 
ATOM   6213 C CZ  . PHE D 4 212 ? 142.003 101.305 159.820 1.00 79.81  ?  212 PHE S CZ  1 
ATOM   6214 N N   . THR D 4 213 ? 140.517 100.117 166.730 1.00 82.79  ?  213 THR S N   1 
ATOM   6215 C CA  . THR D 4 213 ? 139.938 99.835  168.033 1.00 82.79  ?  213 THR S CA  1 
ATOM   6216 C C   . THR D 4 213 ? 139.000 100.958 168.451 1.00 82.79  ?  213 THR S C   1 
ATOM   6217 O O   . THR D 4 213 ? 139.160 102.116 168.053 1.00 82.79  ?  213 THR S O   1 
ATOM   6218 C CB  . THR D 4 213 ? 141.023 99.633  169.103 1.00 82.79  ?  213 THR S CB  1 
ATOM   6219 O OG1 . THR D 4 213 ? 140.411 99.258  170.343 1.00 82.79  ?  213 THR S OG1 1 
ATOM   6220 C CG2 . THR D 4 213 ? 141.830 100.905 169.302 1.00 82.79  ?  213 THR S CG2 1 
ATOM   6221 N N   . LEU D 4 214 ? 138.003 100.584 169.249 1.00 83.23  ?  214 LEU S N   1 
ATOM   6222 C CA  . LEU D 4 214 ? 137.054 101.515 169.847 1.00 83.23  ?  214 LEU S CA  1 
ATOM   6223 C C   . LEU D 4 214 ? 137.066 101.292 171.351 1.00 83.23  ?  214 LEU S C   1 
ATOM   6224 O O   . LEU D 4 214 ? 136.832 100.171 171.812 1.00 83.23  ?  214 LEU S O   1 
ATOM   6225 C CB  . LEU D 4 214 ? 135.645 101.312 169.283 1.00 83.23  ?  214 LEU S CB  1 
ATOM   6226 C CG  . LEU D 4 214 ? 134.552 102.236 169.821 1.00 83.23  ?  214 LEU S CG  1 
ATOM   6227 C CD1 . LEU D 4 214 ? 134.817 103.675 169.413 1.00 83.23  ?  214 LEU S CD1 1 
ATOM   6228 C CD2 . LEU D 4 214 ? 133.183 101.783 169.347 1.00 83.23  ?  214 LEU S CD2 1 
ATOM   6229 N N   . THR D 4 215 ? 137.334 102.348 172.110 1.00 91.46  ?  215 THR S N   1 
ATOM   6230 C CA  . THR D 4 215 ? 137.494 102.264 173.553 1.00 91.46  ?  215 THR S CA  1 
ATOM   6231 C C   . THR D 4 215 ? 136.357 103.004 174.241 1.00 91.46  ?  215 THR S C   1 
ATOM   6232 O O   . THR D 4 215 ? 136.064 104.158 173.904 1.00 91.46  ?  215 THR S O   1 
ATOM   6233 C CB  . THR D 4 215 ? 138.841 102.847 173.988 1.00 91.46  ?  215 THR S CB  1 
ATOM   6234 O OG1 . THR D 4 215 ? 139.903 102.126 173.351 1.00 91.46  ?  215 THR S OG1 1 
ATOM   6235 C CG2 . THR D 4 215 ? 139.003 102.747 175.497 1.00 91.46  ?  215 THR S CG2 1 
ATOM   6236 N N   . ILE D 4 216 ? 135.718 102.331 175.194 1.00 98.76  ?  216 ILE S N   1 
ATOM   6237 C CA  . ILE D 4 216 ? 134.701 102.921 176.054 1.00 98.76  ?  216 ILE S CA  1 
ATOM   6238 C C   . ILE D 4 216 ? 135.283 102.989 177.458 1.00 98.76  ?  216 ILE S C   1 
ATOM   6239 O O   . ILE D 4 216 ? 135.602 101.953 178.056 1.00 98.76  ?  216 ILE S O   1 
ATOM   6240 C CB  . ILE D 4 216 ? 133.399 102.107 176.033 1.00 98.76  ?  216 ILE S CB  1 
ATOM   6241 C CG1 . ILE D 4 216 ? 132.937 101.888 174.593 1.00 98.76  ?  216 ILE S CG1 1 
ATOM   6242 C CG2 . ILE D 4 216 ? 132.319 102.812 176.836 1.00 98.76  ?  216 ILE S CG2 1 
ATOM   6243 C CD1 . ILE D 4 216 ? 131.891 100.813 174.450 1.00 98.76  ?  216 ILE S CD1 1 
ATOM   6244 N N   . SER D 4 217 ? 135.424 104.207 177.982 1.00 104.19 ?  217 SER S N   1 
ATOM   6245 C CA  . SER D 4 217 ? 136.112 104.400 179.255 1.00 104.19 ?  217 SER S CA  1 
ATOM   6246 C C   . SER D 4 217 ? 135.224 104.025 180.437 1.00 104.19 ?  217 SER S C   1 
ATOM   6247 O O   . SER D 4 217 ? 135.544 103.109 181.201 1.00 104.19 ?  217 SER S O   1 
ATOM   6248 C CB  . SER D 4 217 ? 136.587 105.849 179.374 1.00 104.19 ?  217 SER S CB  1 
ATOM   6249 O OG  . SER D 4 217 ? 135.494 106.748 179.323 1.00 104.19 ?  217 SER S OG  1 
ATOM   6250 N N   . ARG D 4 218 ? 134.105 104.724 180.603 1.00 108.50 ?  218 ARG S N   1 
ATOM   6251 C CA  . ARG D 4 218 ? 133.158 104.457 181.684 1.00 108.50 ?  218 ARG S CA  1 
ATOM   6252 C C   . ARG D 4 218 ? 131.887 103.893 181.056 1.00 108.50 ?  218 ARG S C   1 
ATOM   6253 O O   . ARG D 4 218 ? 130.962 104.634 180.719 1.00 108.50 ?  218 ARG S O   1 
ATOM   6254 C CB  . ARG D 4 218 ? 132.861 105.717 182.502 1.00 108.50 ?  218 ARG S CB  1 
ATOM   6255 C CG  . ARG D 4 218 ? 133.930 106.091 183.521 1.00 108.50 ?  218 ARG S CG  1 
ATOM   6256 C CD  . ARG D 4 218 ? 135.085 106.853 182.891 1.00 108.50 ?  218 ARG S CD  1 
ATOM   6257 N NE  . ARG D 4 218 ? 134.655 108.150 182.380 1.00 108.50 ?  218 ARG S NE  1 
ATOM   6258 C CZ  . ARG D 4 218 ? 135.375 108.917 181.573 1.00 108.50 ?  218 ARG S CZ  1 
ATOM   6259 N NH1 . ARG D 4 218 ? 136.586 108.561 181.179 1.00 108.50 1  218 ARG S NH1 1 
ATOM   6260 N NH2 . ARG D 4 218 ? 134.868 110.074 181.155 1.00 108.50 ?  218 ARG S NH2 1 
ATOM   6261 N N   . LEU D 4 219 ? 131.844 102.573 180.904 1.00 110.00 ?  219 LEU S N   1 
ATOM   6262 C CA  . LEU D 4 219 ? 130.688 101.907 180.308 1.00 110.00 ?  219 LEU S CA  1 
ATOM   6263 C C   . LEU D 4 219 ? 129.515 102.011 181.273 1.00 110.00 ?  219 LEU S C   1 
ATOM   6264 O O   . LEU D 4 219 ? 129.468 101.322 182.294 1.00 110.00 ?  219 LEU S O   1 
ATOM   6265 C CB  . LEU D 4 219 ? 131.020 100.455 179.980 1.00 110.00 ?  219 LEU S CB  1 
ATOM   6266 C CG  . LEU D 4 219 ? 130.003 99.624  179.188 1.00 110.00 ?  219 LEU S CG  1 
ATOM   6267 C CD1 . LEU D 4 219 ? 130.719 98.532  178.423 1.00 110.00 ?  219 LEU S CD1 1 
ATOM   6268 C CD2 . LEU D 4 219 ? 128.944 99.002  180.087 1.00 110.00 ?  219 LEU S CD2 1 
ATOM   6269 N N   . GLU D 4 220 ? 128.566 102.883 180.955 1.00 108.18 ?  220 GLU S N   1 
ATOM   6270 C CA  . GLU D 4 220 ? 127.348 103.022 181.735 1.00 108.18 ?  220 GLU S CA  1 
ATOM   6271 C C   . GLU D 4 220 ? 126.262 102.131 181.134 1.00 108.18 ?  220 GLU S C   1 
ATOM   6272 O O   . GLU D 4 220 ? 126.527 101.277 180.283 1.00 108.18 ?  220 GLU S O   1 
ATOM   6273 C CB  . GLU D 4 220 ? 126.920 104.486 181.795 1.00 108.18 ?  220 GLU S CB  1 
ATOM   6274 C CG  . GLU D 4 220 ? 126.464 105.056 180.463 1.00 108.18 ?  220 GLU S CG  1 
ATOM   6275 C CD  . GLU D 4 220 ? 125.882 106.448 180.596 1.00 108.18 ?  220 GLU S CD  1 
ATOM   6276 O OE1 . GLU D 4 220 ? 125.888 106.992 181.720 1.00 108.18 ?  220 GLU S OE1 1 
ATOM   6277 O OE2 . GLU D 4 220 ? 125.415 106.998 179.576 1.00 108.18 -1 220 GLU S OE2 1 
ATOM   6278 N N   . ALA D 4 221 ? 125.021 102.322 181.573 1.00 107.34 ?  221 ALA S N   1 
ATOM   6279 C CA  . ALA D 4 221 ? 123.900 101.604 180.990 1.00 107.34 ?  221 ALA S CA  1 
ATOM   6280 C C   . ALA D 4 221 ? 123.627 102.122 179.578 1.00 107.34 ?  221 ALA S C   1 
ATOM   6281 O O   . ALA D 4 221 ? 124.353 102.966 179.044 1.00 107.34 ?  221 ALA S O   1 
ATOM   6282 C CB  . ALA D 4 221 ? 122.664 101.738 181.876 1.00 107.34 ?  221 ALA S CB  1 
ATOM   6283 N N   . GLU D 4 222 ? 122.576 101.576 178.959 1.00 105.06 ?  222 GLU S N   1 
ATOM   6284 C CA  . GLU D 4 222 ? 122.130 101.910 177.598 1.00 105.06 ?  222 GLU S CA  1 
ATOM   6285 C C   . GLU D 4 222 ? 123.286 101.944 176.595 1.00 105.06 ?  222 GLU S C   1 
ATOM   6286 O O   . GLU D 4 222 ? 123.192 102.585 175.545 1.00 105.06 ?  222 GLU S O   1 
ATOM   6287 C CB  . GLU D 4 222 ? 121.318 103.220 177.564 1.00 105.06 ?  222 GLU S CB  1 
ATOM   6288 C CG  . GLU D 4 222 ? 122.014 104.504 178.019 1.00 105.06 ?  222 GLU S CG  1 
ATOM   6289 C CD  . GLU D 4 222 ? 122.681 105.267 176.889 1.00 105.06 ?  222 GLU S CD  1 
ATOM   6290 O OE1 . GLU D 4 222 ? 122.279 105.084 175.721 1.00 105.06 ?  222 GLU S OE1 1 
ATOM   6291 O OE2 . GLU D 4 222 ? 123.611 106.051 177.171 1.00 105.06 -1 222 GLU S OE2 1 
ATOM   6292 N N   . ASP D 4 223 ? 124.372 101.228 176.890 1.00 99.94  ?  223 ASP S N   1 
ATOM   6293 C CA  . ASP D 4 223 ? 125.479 101.063 175.963 1.00 99.94  ?  223 ASP S CA  1 
ATOM   6294 C C   . ASP D 4 223 ? 125.611 99.640  175.446 1.00 99.94  ?  223 ASP S C   1 
ATOM   6295 O O   . ASP D 4 223 ? 126.402 99.403  174.527 1.00 99.94  ?  223 ASP S O   1 
ATOM   6296 C CB  . ASP D 4 223 ? 126.800 101.486 176.623 1.00 99.94  ?  223 ASP S CB  1 
ATOM   6297 C CG  . ASP D 4 223 ? 127.066 102.972 176.495 1.00 99.94  ?  223 ASP S CG  1 
ATOM   6298 O OD1 . ASP D 4 223 ? 126.172 103.697 176.013 1.00 99.94  ?  223 ASP S OD1 1 
ATOM   6299 O OD2 . ASP D 4 223 ? 128.170 103.415 176.876 1.00 99.94  -1 223 ASP S OD2 1 
ATOM   6300 N N   . VAL D 4 224 ? 124.865 98.690  176.013 1.00 96.79  ?  224 VAL S N   1 
ATOM   6301 C CA  . VAL D 4 224 ? 124.899 97.318  175.527 1.00 96.79  ?  224 VAL S CA  1 
ATOM   6302 C C   . VAL D 4 224 ? 124.252 97.249  174.151 1.00 96.79  ?  224 VAL S C   1 
ATOM   6303 O O   . VAL D 4 224 ? 123.240 97.910  173.881 1.00 96.79  ?  224 VAL S O   1 
ATOM   6304 C CB  . VAL D 4 224 ? 124.207 96.375  176.526 1.00 96.79  ?  224 VAL S CB  1 
ATOM   6305 C CG1 . VAL D 4 224 ? 125.014 96.285  177.810 1.00 96.79  ?  224 VAL S CG1 1 
ATOM   6306 C CG2 . VAL D 4 224 ? 122.794 96.852  176.823 1.00 96.79  ?  224 VAL S CG2 1 
ATOM   6307 N N   . GLY D 4 225 ? 124.846 96.458  173.270 1.00 89.11  ?  225 GLY S N   1 
ATOM   6308 C CA  . GLY D 4 225 ? 124.366 96.356  171.905 1.00 89.11  ?  225 GLY S CA  1 
ATOM   6309 C C   . GLY D 4 225 ? 125.408 95.669  171.042 1.00 89.11  ?  225 GLY S C   1 
ATOM   6310 O O   . GLY D 4 225 ? 126.316 95.014  171.549 1.00 89.11  ?  225 GLY S O   1 
ATOM   6311 N N   . VAL D 4 226 ? 125.257 95.841  169.733 1.00 80.41  ?  226 VAL S N   1 
ATOM   6312 C CA  . VAL D 4 226 ? 126.158 95.244  168.755 1.00 80.41  ?  226 VAL S CA  1 
ATOM   6313 C C   . VAL D 4 226 ? 126.931 96.362  168.069 1.00 80.41  ?  226 VAL S C   1 
ATOM   6314 O O   . VAL D 4 226 ? 126.335 97.332  167.584 1.00 80.41  ?  226 VAL S O   1 
ATOM   6315 C CB  . VAL D 4 226 ? 125.394 94.388  167.731 1.00 80.41  ?  226 VAL S CB  1 
ATOM   6316 C CG1 . VAL D 4 226 ? 126.362 93.757  166.748 1.00 80.41  ?  226 VAL S CG1 1 
ATOM   6317 C CG2 . VAL D 4 226 ? 124.574 93.322  168.440 1.00 80.41  ?  226 VAL S CG2 1 
ATOM   6318 N N   . TYR D 4 227 ? 128.253 96.228  168.031 1.00 78.92  ?  227 TYR S N   1 
ATOM   6319 C CA  . TYR D 4 227 ? 129.132 97.230  167.444 1.00 78.92  ?  227 TYR S CA  1 
ATOM   6320 C C   . TYR D 4 227 ? 129.606 96.758  166.076 1.00 78.92  ?  227 TYR S C   1 
ATOM   6321 O O   . TYR D 4 227 ? 130.085 95.628  165.935 1.00 78.92  ?  227 TYR S O   1 
ATOM   6322 C CB  . TYR D 4 227 ? 130.334 97.502  168.351 1.00 78.92  ?  227 TYR S CB  1 
ATOM   6323 C CG  . TYR D 4 227 ? 129.984 98.188  169.651 1.00 78.92  ?  227 TYR S CG  1 
ATOM   6324 C CD1 . TYR D 4 227 ? 129.535 97.461  170.744 1.00 78.92  ?  227 TYR S CD1 1 
ATOM   6325 C CD2 . TYR D 4 227 ? 130.104 99.564  169.784 1.00 78.92  ?  227 TYR S CD2 1 
ATOM   6326 C CE1 . TYR D 4 227 ? 129.215 98.084  171.933 1.00 78.92  ?  227 TYR S CE1 1 
ATOM   6327 C CE2 . TYR D 4 227 ? 129.787 100.197 170.970 1.00 78.92  ?  227 TYR S CE2 1 
ATOM   6328 C CZ  . TYR D 4 227 ? 129.343 99.452  172.041 1.00 78.92  ?  227 TYR S CZ  1 
ATOM   6329 O OH  . TYR D 4 227 ? 129.022 100.076 173.223 1.00 78.92  ?  227 TYR S OH  1 
ATOM   6330 N N   . TYR D 4 228 ? 129.475 97.625  165.076 1.00 71.85  ?  228 TYR S N   1 
ATOM   6331 C CA  . TYR D 4 228 ? 129.868 97.319  163.708 1.00 71.85  ?  228 TYR S CA  1 
ATOM   6332 C C   . TYR D 4 228 ? 130.951 98.283  163.246 1.00 71.85  ?  228 TYR S C   1 
ATOM   6333 O O   . TYR D 4 228 ? 130.870 99.489  163.498 1.00 71.85  ?  228 TYR S O   1 
ATOM   6334 C CB  . TYR D 4 228 ? 128.673 97.401  162.751 1.00 71.85  ?  228 TYR S CB  1 
ATOM   6335 C CG  . TYR D 4 228 ? 127.554 96.433  163.057 1.00 71.85  ?  228 TYR S CG  1 
ATOM   6336 C CD1 . TYR D 4 228 ? 127.603 95.121  162.607 1.00 71.85  ?  228 TYR S CD1 1 
ATOM   6337 C CD2 . TYR D 4 228 ? 126.445 96.833  163.788 1.00 71.85  ?  228 TYR S CD2 1 
ATOM   6338 C CE1 . TYR D 4 228 ? 126.582 94.235  162.881 1.00 71.85  ?  228 TYR S CE1 1 
ATOM   6339 C CE2 . TYR D 4 228 ? 125.419 95.954  164.065 1.00 71.85  ?  228 TYR S CE2 1 
ATOM   6340 C CZ  . TYR D 4 228 ? 125.492 94.657  163.608 1.00 71.85  ?  228 TYR S CZ  1 
ATOM   6341 O OH  . TYR D 4 228 ? 124.472 93.778  163.886 1.00 71.85  ?  228 TYR S OH  1 
ATOM   6342 N N   . CYS D 4 229 ? 131.962 97.745  162.570 1.00 72.88  ?  229 CYS S N   1 
ATOM   6343 C CA  . CYS D 4 229 ? 132.989 98.544  161.918 1.00 72.88  ?  229 CYS S CA  1 
ATOM   6344 C C   . CYS D 4 229 ? 132.806 98.438  160.411 1.00 72.88  ?  229 CYS S C   1 
ATOM   6345 O O   . CYS D 4 229 ? 132.730 97.333  159.865 1.00 72.88  ?  229 CYS S O   1 
ATOM   6346 C CB  . CYS D 4 229 ? 134.398 98.100  162.328 1.00 72.88  ?  229 CYS S CB  1 
ATOM   6347 S SG  . CYS D 4 229 ? 134.791 96.355  162.066 1.00 72.88  ?  229 CYS S SG  1 
ATOM   6348 N N   . MET D 4 230 ? 132.727 99.586  159.750 1.00 64.31  ?  230 MET S N   1 
ATOM   6349 C CA  . MET D 4 230 ? 132.421 99.676  158.332 1.00 64.31  ?  230 MET S CA  1 
ATOM   6350 C C   . MET D 4 230 ? 133.540 100.411 157.607 1.00 64.31  ?  230 MET S C   1 
ATOM   6351 O O   . MET D 4 230 ? 134.135 101.346 158.145 1.00 64.31  ?  230 MET S O   1 
ATOM   6352 C CB  . MET D 4 230 ? 131.087 100.401 158.118 1.00 64.31  ?  230 MET S CB  1 
ATOM   6353 C CG  . MET D 4 230 ? 130.644 100.521 156.676 1.00 64.31  ?  230 MET S CG  1 
ATOM   6354 S SD  . MET D 4 230 ? 129.441 101.846 156.472 1.00 64.31  ?  230 MET S SD  1 
ATOM   6355 C CE  . MET D 4 230 ? 130.521 103.237 156.155 1.00 64.31  ?  230 MET S CE  1 
ATOM   6356 N N   . GLN D 4 231 ? 133.828 99.981  156.383 1.00 66.39  ?  231 GLN S N   1 
ATOM   6357 C CA  . GLN D 4 231 ? 134.844 100.618 155.559 1.00 66.39  ?  231 GLN S CA  1 
ATOM   6358 C C   . GLN D 4 231 ? 134.190 101.472 154.481 1.00 66.39  ?  231 GLN S C   1 
ATOM   6359 O O   . GLN D 4 231 ? 133.088 101.178 154.010 1.00 66.39  ?  231 GLN S O   1 
ATOM   6360 C CB  . GLN D 4 231 ? 135.766 99.577  154.919 1.00 66.39  ?  231 GLN S CB  1 
ATOM   6361 C CG  . GLN D 4 231 ? 135.120 98.741  153.827 1.00 66.39  ?  231 GLN S CG  1 
ATOM   6362 C CD  . GLN D 4 231 ? 135.324 99.323  152.442 1.00 66.39  ?  231 GLN S CD  1 
ATOM   6363 O OE1 . GLN D 4 231 ? 135.999 100.339 152.275 1.00 66.39  ?  231 GLN S OE1 1 
ATOM   6364 N NE2 . GLN D 4 231 ? 134.736 98.683  151.441 1.00 66.39  ?  231 GLN S NE2 1 
ATOM   6365 N N   . HIS D 4 232 ? 134.876 102.550 154.102 1.00 62.21  ?  232 HIS S N   1 
ATOM   6366 C CA  . HIS D 4 232 ? 134.380 103.442 153.064 1.00 62.21  ?  232 HIS S CA  1 
ATOM   6367 C C   . HIS D 4 232 ? 135.446 103.777 152.029 1.00 62.21  ?  232 HIS S C   1 
ATOM   6368 O O   . HIS D 4 232 ? 135.278 104.743 151.277 1.00 62.21  ?  232 HIS S O   1 
ATOM   6369 C CB  . HIS D 4 232 ? 133.841 104.733 153.689 1.00 62.21  ?  232 HIS S CB  1 
ATOM   6370 C CG  . HIS D 4 232 ? 132.665 105.315 152.969 1.00 62.21  ?  232 HIS S CG  1 
ATOM   6371 N ND1 . HIS D 4 232 ? 132.774 105.970 151.761 1.00 62.21  ?  232 HIS S ND1 1 
ATOM   6372 C CD2 . HIS D 4 232 ? 131.352 105.351 153.298 1.00 62.21  ?  232 HIS S CD2 1 
ATOM   6373 C CE1 . HIS D 4 232 ? 131.578 106.377 151.374 1.00 62.21  ?  232 HIS S CE1 1 
ATOM   6374 N NE2 . HIS D 4 232 ? 130.698 106.014 152.289 1.00 62.21  ?  232 HIS S NE2 1 
ATOM   6375 N N   . LEU D 4 233 ? 136.540 103.016 151.971 1.00 68.39  ?  233 LEU S N   1 
ATOM   6376 C CA  . LEU D 4 233 ? 137.634 103.353 151.059 1.00 68.39  ?  233 LEU S CA  1 
ATOM   6377 C C   . LEU D 4 233 ? 137.373 102.808 149.658 1.00 68.39  ?  233 LEU S C   1 
ATOM   6378 O O   . LEU D 4 233 ? 137.153 103.572 148.713 1.00 68.39  ?  233 LEU S O   1 
ATOM   6379 C CB  . LEU D 4 233 ? 138.956 102.819 151.616 1.00 68.39  ?  233 LEU S CB  1 
ATOM   6380 C CG  . LEU D 4 233 ? 140.181 103.019 150.727 1.00 68.39  ?  233 LEU S CG  1 
ATOM   6381 C CD1 . LEU D 4 233 ? 140.604 104.474 150.747 1.00 68.39  ?  233 LEU S CD1 1 
ATOM   6382 C CD2 . LEU D 4 233 ? 141.316 102.115 151.168 1.00 68.39  ?  233 LEU S CD2 1 
ATOM   6383 N N   . GLU D 4 234 ? 136.978 101.554 149.573 1.00 72.71  ?  234 GLU S N   1 
ATOM   6384 C CA  . GLU D 4 234 ? 136.527 101.045 148.282 1.00 72.71  ?  234 GLU S CA  1 
ATOM   6385 C C   . GLU D 4 234 ? 135.013 101.141 148.371 1.00 72.71  ?  234 GLU S C   1 
ATOM   6386 O O   . GLU D 4 234 ? 134.496 101.364 149.451 1.00 72.71  ?  234 GLU S O   1 
ATOM   6387 C CB  . GLU D 4 234 ? 136.990 99.622  148.049 1.00 72.71  ?  234 GLU S CB  1 
ATOM   6388 C CG  . GLU D 4 234 ? 138.497 99.456  148.030 1.00 72.71  ?  234 GLU S CG  1 
ATOM   6389 C CD  . GLU D 4 234 ? 139.190 100.541 147.234 1.00 72.71  ?  234 GLU S CD  1 
ATOM   6390 O OE1 . GLU D 4 234 ? 140.076 101.218 147.795 1.00 72.71  ?  234 GLU S OE1 1 
ATOM   6391 O OE2 . GLU D 4 234 ? 138.848 100.716 146.047 1.00 72.71  -1 234 GLU S OE2 1 
ATOM   6392 N N   . TYR D 4 235 ? 134.268 100.951 147.288 1.00 68.71  ?  235 TYR S N   1 
ATOM   6393 C CA  . TYR D 4 235 ? 132.810 101.161 147.395 1.00 68.71  ?  235 TYR S CA  1 
ATOM   6394 C C   . TYR D 4 235 ? 131.879 100.002 147.712 1.00 68.71  ?  235 TYR S C   1 
ATOM   6395 O O   . TYR D 4 235 ? 130.770 100.227 148.157 1.00 68.71  ?  235 TYR S O   1 
ATOM   6396 C CB  . TYR D 4 235 ? 132.210 101.886 146.189 1.00 68.71  ?  235 TYR S CB  1 
ATOM   6397 C CG  . TYR D 4 235 ? 131.177 102.867 146.685 1.00 68.71  ?  235 TYR S CG  1 
ATOM   6398 C CD1 . TYR D 4 235 ? 131.553 104.115 147.136 1.00 68.71  ?  235 TYR S CD1 1 
ATOM   6399 C CD2 . TYR D 4 235 ? 129.842 102.517 146.779 1.00 68.71  ?  235 TYR S CD2 1 
ATOM   6400 C CE1 . TYR D 4 235 ? 130.628 105.007 147.627 1.00 68.71  ?  235 TYR S CE1 1 
ATOM   6401 C CE2 . TYR D 4 235 ? 128.910 103.400 147.275 1.00 68.71  ?  235 TYR S CE2 1 
ATOM   6402 C CZ  . TYR D 4 235 ? 129.313 104.645 147.693 1.00 68.71  ?  235 TYR S CZ  1 
ATOM   6403 O OH  . TYR D 4 235 ? 128.398 105.539 148.182 1.00 68.71  ?  235 TYR S OH  1 
ATOM   6404 N N   . PRO D 4 236 ? 132.276 98.772  147.442 1.00 69.69  ?  236 PRO S N   1 
ATOM   6405 C CA  . PRO D 4 236 ? 131.325 97.747  147.873 1.00 69.69  ?  236 PRO S CA  1 
ATOM   6406 C C   . PRO D 4 236 ? 131.416 97.729  149.395 1.00 69.69  ?  236 PRO S C   1 
ATOM   6407 O O   . PRO D 4 236 ? 131.970 96.779  149.928 1.00 69.69  ?  236 PRO S O   1 
ATOM   6408 C CB  . PRO D 4 236 ? 131.884 96.481  147.277 1.00 69.69  ?  236 PRO S CB  1 
ATOM   6409 C CG  . PRO D 4 236 ? 132.576 96.928  146.038 1.00 69.69  ?  236 PRO S CG  1 
ATOM   6410 C CD  . PRO D 4 236 ? 133.164 98.265  146.367 1.00 69.69  ?  236 PRO S CD  1 
ATOM   6411 N N   . LEU D 4 237 ? 130.905 98.746  150.085 1.00 62.71  ?  237 LEU S N   1 
ATOM   6412 C CA  . LEU D 4 237 ? 130.997 98.852  151.541 1.00 62.71  ?  237 LEU S CA  1 
ATOM   6413 C C   . LEU D 4 237 ? 130.689 97.564  152.271 1.00 62.71  ?  237 LEU S C   1 
ATOM   6414 O O   . LEU D 4 237 ? 129.695 96.923  151.984 1.00 62.71  ?  237 LEU S O   1 
ATOM   6415 C CB  . LEU D 4 237 ? 130.060 99.952  152.018 1.00 62.71  ?  237 LEU S CB  1 
ATOM   6416 C CG  . LEU D 4 237 ? 130.382 101.443 151.892 1.00 62.71  ?  237 LEU S CG  1 
ATOM   6417 C CD1 . LEU D 4 237 ? 131.513 101.736 150.928 1.00 62.71  ?  237 LEU S CD1 1 
ATOM   6418 C CD2 . LEU D 4 237 ? 129.141 102.222 151.501 1.00 62.71  ?  237 LEU S CD2 1 
ATOM   6419 N N   . THR D 4 238 ? 131.519 97.182  153.223 1.00 66.00  ?  238 THR S N   1 
ATOM   6420 C CA  . THR D 4 238 ? 131.369 95.940  153.962 1.00 66.00  ?  238 THR S CA  1 
ATOM   6421 C C   . THR D 4 238 ? 131.396 96.237  155.452 1.00 66.00  ?  238 THR S C   1 
ATOM   6422 O O   . THR D 4 238 ? 132.182 97.068  155.915 1.00 66.00  ?  238 THR S O   1 
ATOM   6423 C CB  . THR D 4 238 ? 132.475 94.939  153.606 1.00 66.00  ?  238 THR S CB  1 
ATOM   6424 O OG1 . THR D 4 238 ? 133.741 95.609  153.589 1.00 66.00  ?  238 THR S OG1 1 
ATOM   6425 C CG2 . THR D 4 238 ? 132.216 94.320  152.242 1.00 66.00  ?  238 THR S CG2 1 
ATOM   6426 N N   . PHE D 4 239 ? 130.533 95.556  156.196 1.00 64.48  ?  239 PHE S N   1 
ATOM   6427 C CA  . PHE D 4 239 ? 130.448 95.707  157.638 1.00 64.48  ?  239 PHE S CA  1 
ATOM   6428 C C   . PHE D 4 239 ? 131.122 94.526  158.319 1.00 64.48  ?  239 PHE S C   1 
ATOM   6429 O O   . PHE D 4 239 ? 131.325 93.466  157.721 1.00 64.48  ?  239 PHE S O   1 
ATOM   6430 C CB  . PHE D 4 239 ? 128.989 95.806  158.100 1.00 64.48  ?  239 PHE S CB  1 
ATOM   6431 C CG  . PHE D 4 239 ? 128.293 97.062  157.662 1.00 64.48  ?  239 PHE S CG  1 
ATOM   6432 C CD1 . PHE D 4 239 ? 127.729 97.151  156.403 1.00 64.48  ?  239 PHE S CD1 1 
ATOM   6433 C CD2 . PHE D 4 239 ? 128.188 98.146  158.515 1.00 64.48  ?  239 PHE S CD2 1 
ATOM   6434 C CE1 . PHE D 4 239 ? 127.084 98.301  155.998 1.00 64.48  ?  239 PHE S CE1 1 
ATOM   6435 C CE2 . PHE D 4 239 ? 127.543 99.298  158.115 1.00 64.48  ?  239 PHE S CE2 1 
ATOM   6436 C CZ  . PHE D 4 239 ? 126.990 99.375  156.855 1.00 64.48  ?  239 PHE S CZ  1 
ATOM   6437 N N   . GLY D 4 240 ? 131.469 94.720  159.585 1.00 72.58  ?  240 GLY S N   1 
ATOM   6438 C CA  . GLY D 4 240 ? 132.011 93.636  160.369 1.00 72.58  ?  240 GLY S CA  1 
ATOM   6439 C C   . GLY D 4 240 ? 130.945 92.635  160.758 1.00 72.58  ?  240 GLY S C   1 
ATOM   6440 O O   . GLY D 4 240 ? 129.750 92.839  160.547 1.00 72.58  ?  240 GLY S O   1 
ATOM   6441 N N   . ALA D 4 241 ? 131.399 91.520  161.333 1.00 79.49  ?  241 ALA S N   1 
ATOM   6442 C CA  . ALA D 4 241 ? 130.464 90.501  161.794 1.00 79.49  ?  241 ALA S CA  1 
ATOM   6443 C C   . ALA D 4 241 ? 129.558 91.046  162.889 1.00 79.49  ?  241 ALA S C   1 
ATOM   6444 O O   . ALA D 4 241 ? 128.360 90.741  162.926 1.00 79.49  ?  241 ALA S O   1 
ATOM   6445 C CB  . ALA D 4 241 ? 131.226 89.272  162.286 1.00 79.49  ?  241 ALA S CB  1 
ATOM   6446 N N   . GLY D 4 242 ? 130.110 91.857  163.787 1.00 84.10  ?  242 GLY S N   1 
ATOM   6447 C CA  . GLY D 4 242 ? 129.336 92.439  164.863 1.00 84.10  ?  242 GLY S CA  1 
ATOM   6448 C C   . GLY D 4 242 ? 129.706 91.870  166.215 1.00 84.10  ?  242 GLY S C   1 
ATOM   6449 O O   . GLY D 4 242 ? 129.602 90.660  166.435 1.00 84.10  ?  242 GLY S O   1 
ATOM   6450 N N   . THR D 4 243 ? 130.141 92.730  167.130 1.00 89.40  ?  243 THR S N   1 
ATOM   6451 C CA  . THR D 4 243 ? 130.493 92.327  168.485 1.00 89.40  ?  243 THR S CA  1 
ATOM   6452 C C   . THR D 4 243 ? 129.401 92.805  169.430 1.00 89.40  ?  243 THR S C   1 
ATOM   6453 O O   . THR D 4 243 ? 129.068 93.994  169.449 1.00 89.40  ?  243 THR S O   1 
ATOM   6454 C CB  . THR D 4 243 ? 131.849 92.896  168.900 1.00 89.40  ?  243 THR S CB  1 
ATOM   6455 O OG1 . THR D 4 243 ? 132.771 92.779  167.811 1.00 89.40  ?  243 THR S OG1 1 
ATOM   6456 C CG2 . THR D 4 243 ? 132.390 92.130  170.095 1.00 89.40  ?  243 THR S CG2 1 
ATOM   6457 N N   . LYS D 4 244 ? 128.855 91.882  170.215 1.00 96.93  ?  244 LYS S N   1 
ATOM   6458 C CA  . LYS D 4 244 ? 127.735 92.159  171.100 1.00 96.93  ?  244 LYS S CA  1 
ATOM   6459 C C   . LYS D 4 244 ? 128.215 92.242  172.542 1.00 96.93  ?  244 LYS S C   1 
ATOM   6460 O O   . LYS D 4 244 ? 128.993 91.398  172.997 1.00 96.93  ?  244 LYS S O   1 
ATOM   6461 C CB  . LYS D 4 244 ? 126.654 91.084  170.960 1.00 96.93  ?  244 LYS S CB  1 
ATOM   6462 C CG  . LYS D 4 244 ? 125.424 91.310  171.820 1.00 96.93  ?  244 LYS S CG  1 
ATOM   6463 C CD  . LYS D 4 244 ? 124.348 90.282  171.509 1.00 96.93  ?  244 LYS S CD  1 
ATOM   6464 C CE  . LYS D 4 244 ? 124.727 88.905  172.027 1.00 96.93  ?  244 LYS S CE  1 
ATOM   6465 N NZ  . LYS D 4 244 ? 124.732 88.853  173.512 1.00 96.93  1  244 LYS S NZ  1 
ATOM   6466 N N   . LEU D 4 245 ? 127.751 93.264  173.253 1.00 99.25  ?  245 LEU S N   1 
ATOM   6467 C CA  . LEU D 4 245 ? 128.122 93.489  174.643 1.00 99.25  ?  245 LEU S CA  1 
ATOM   6468 C C   . LEU D 4 245 ? 127.012 92.981  175.553 1.00 99.25  ?  245 LEU S C   1 
ATOM   6469 O O   . LEU D 4 245 ? 125.835 93.291  175.339 1.00 99.25  ?  245 LEU S O   1 
ATOM   6470 C CB  . LEU D 4 245 ? 128.386 94.972  174.905 1.00 99.25  ?  245 LEU S CB  1 
ATOM   6471 C CG  . LEU D 4 245 ? 129.854 95.401  174.951 1.00 99.25  ?  245 LEU S CG  1 
ATOM   6472 C CD1 . LEU D 4 245 ? 130.572 95.016  173.667 1.00 99.25  ?  245 LEU S CD1 1 
ATOM   6473 C CD2 . LEU D 4 245 ? 129.967 96.894  175.205 1.00 99.25  ?  245 LEU S CD2 1 
ATOM   6474 N N   . GLU D 4 246 ? 127.390 92.205  176.563 1.00 110.36 ?  246 GLU S N   1 
ATOM   6475 C CA  . GLU D 4 246 ? 126.450 91.588  177.486 1.00 110.36 ?  246 GLU S CA  1 
ATOM   6476 C C   . GLU D 4 246 ? 126.557 92.232  178.862 1.00 110.36 ?  246 GLU S C   1 
ATOM   6477 O O   . GLU D 4 246 ? 127.456 93.032  179.136 1.00 110.36 ?  246 GLU S O   1 
ATOM   6478 C CB  . GLU D 4 246 ? 126.702 90.079  177.586 1.00 110.36 ?  246 GLU S CB  1 
ATOM   6479 C CG  . GLU D 4 246 ? 126.026 89.262  176.501 1.00 110.36 ?  246 GLU S CG  1 
ATOM   6480 C CD  . GLU D 4 246 ? 124.571 88.971  176.811 1.00 110.36 ?  246 GLU S CD  1 
ATOM   6481 O OE1 . GLU D 4 246 ? 124.231 88.837  178.005 1.00 110.36 ?  246 GLU S OE1 1 
ATOM   6482 O OE2 . GLU D 4 246 ? 123.767 88.876  175.859 1.00 110.36 -1 246 GLU S OE2 1 
ATOM   6483 N N   . LEU D 4 247 ? 125.613 91.867  179.727 1.00 112.66 ?  247 LEU S N   1 
ATOM   6484 C CA  . LEU D 4 247 ? 125.573 92.333  181.112 1.00 112.66 ?  247 LEU S CA  1 
ATOM   6485 C C   . LEU D 4 247 ? 125.551 93.856  181.201 1.00 112.66 ?  247 LEU S C   1 
ATOM   6486 O O   . LEU D 4 247 ? 124.523 94.454  181.517 1.00 112.66 ?  247 LEU S O   1 
ATOM   6487 C CB  . LEU D 4 247 ? 126.765 91.777  181.897 1.00 112.66 ?  247 LEU S CB  1 
ATOM   6488 C CG  . LEU D 4 247 ? 126.598 91.668  183.414 1.00 112.66 ?  247 LEU S CG  1 
ATOM   6489 C CD1 . LEU D 4 247 ? 125.819 90.413  183.778 1.00 112.66 ?  247 LEU S CD1 1 
ATOM   6490 C CD2 . LEU D 4 247 ? 127.952 91.680  184.106 1.00 112.66 ?  247 LEU S CD2 1 
ATOM   6491 N N   . ASN E 5 17  ? 134.583 112.952 82.415  1.00 181.48 1  17  ASN A N   1 
ATOM   6492 C CA  . ASN E 5 17  ? 134.874 112.868 80.993  1.00 181.48 ?  17  ASN A CA  1 
ATOM   6493 C C   . ASN E 5 17  ? 134.889 114.269 80.359  1.00 181.48 ?  17  ASN A C   1 
ATOM   6494 O O   . ASN E 5 17  ? 134.152 114.482 79.395  1.00 181.48 ?  17  ASN A O   1 
ATOM   6495 C CB  . ASN E 5 17  ? 133.843 111.985 80.295  1.00 181.48 ?  17  ASN A CB  1 
ATOM   6496 N N   . CYS E 5 18  ? 135.703 115.224 80.852  1.00 181.46 ?  18  CYS A N   1 
ATOM   6497 C CA  . CYS E 5 18  ? 135.613 116.573 80.230  1.00 181.46 ?  18  CYS A CA  1 
ATOM   6498 C C   . CYS E 5 18  ? 136.543 117.772 80.400  1.00 181.46 ?  18  CYS A C   1 
ATOM   6499 O O   . CYS E 5 18  ? 137.178 117.911 81.440  1.00 181.46 ?  18  CYS A O   1 
ATOM   6500 C CB  . CYS E 5 18  ? 134.254 117.162 80.627  1.00 181.46 ?  18  CYS A CB  1 
ATOM   6501 S SG  . CYS E 5 18  ? 134.316 118.143 82.145  1.00 181.46 ?  18  CYS A SG  1 
ATOM   6502 N N   . CYS E 5 19  ? 136.615 118.621 79.379  1.00 179.93 ?  19  CYS A N   1 
ATOM   6503 C CA  . CYS E 5 19  ? 137.299 119.890 79.358  1.00 179.93 ?  19  CYS A CA  1 
ATOM   6504 C C   . CYS E 5 19  ? 137.993 120.070 80.687  1.00 179.93 ?  19  CYS A C   1 
ATOM   6505 O O   . CYS E 5 19  ? 137.458 120.721 81.582  1.00 179.93 ?  19  CYS A O   1 
ATOM   6506 C CB  . CYS E 5 19  ? 136.572 121.105 78.798  1.00 179.93 ?  19  CYS A CB  1 
ATOM   6507 S SG  . CYS E 5 19  ? 135.521 120.681 77.395  1.00 179.93 ?  19  CYS A SG  1 
ATOM   6508 N N   . VAL E 5 20  ? 139.188 119.510 80.830  1.00 176.52 ?  20  VAL A N   1 
ATOM   6509 C CA  . VAL E 5 20  ? 139.948 119.693 82.055  1.00 176.52 ?  20  VAL A CA  1 
ATOM   6510 C C   . VAL E 5 20  ? 140.690 120.961 81.685  1.00 176.52 ?  20  VAL A C   1 
ATOM   6511 O O   . VAL E 5 20  ? 141.138 121.694 82.562  1.00 176.52 ?  20  VAL A O   1 
ATOM   6512 C CB  . VAL E 5 20  ? 140.939 118.554 82.292  1.00 176.52 ?  20  VAL A CB  1 
ATOM   6513 C CG1 . VAL E 5 20  ? 140.307 117.489 83.174  1.00 176.52 ?  20  VAL A CG1 1 
ATOM   6514 C CG2 . VAL E 5 20  ? 141.382 117.959 80.966  1.00 176.52 ?  20  VAL A CG2 1 
ATOM   6515 N N   . PHE E 5 21  ? 140.836 121.220 80.393  1.00 175.35 ?  21  PHE A N   1 
ATOM   6516 C CA  . PHE E 5 21  ? 141.448 122.464 79.945  1.00 175.35 ?  21  PHE A CA  1 
ATOM   6517 C C   . PHE E 5 21  ? 142.665 122.895 80.740  1.00 175.35 ?  21  PHE A C   1 
ATOM   6518 O O   . PHE E 5 21  ? 142.671 123.981 81.311  1.00 175.35 ?  21  PHE A O   1 
ATOM   6519 C CB  . PHE E 5 21  ? 140.402 123.585 79.977  1.00 175.35 ?  21  PHE A CB  1 
ATOM   6520 C CG  . PHE E 5 21  ? 139.831 123.922 78.633  1.00 175.35 ?  21  PHE A CG  1 
ATOM   6521 C CD1 . PHE E 5 21  ? 140.570 124.637 77.710  1.00 175.35 ?  21  PHE A CD1 1 
ATOM   6522 C CD2 . PHE E 5 21  ? 138.553 123.527 78.295  1.00 175.35 ?  21  PHE A CD2 1 
ATOM   6523 C CE1 . PHE E 5 21  ? 140.043 124.947 76.471  1.00 175.35 ?  21  PHE A CE1 1 
ATOM   6524 C CE2 . PHE E 5 21  ? 138.019 123.829 77.058  1.00 175.35 ?  21  PHE A CE2 1 
ATOM   6525 C CZ  . PHE E 5 21  ? 138.764 124.544 76.144  1.00 175.35 ?  21  PHE A CZ  1 
ATOM   6526 N N   . ARG E 5 22  ? 143.692 122.058 80.804  1.00 174.95 ?  22  ARG A N   1 
ATOM   6527 C CA  . ARG E 5 22  ? 144.931 122.485 81.450  1.00 174.95 ?  22  ARG A CA  1 
ATOM   6528 C C   . ARG E 5 22  ? 145.515 123.444 80.417  1.00 174.95 ?  22  ARG A C   1 
ATOM   6529 O O   . ARG E 5 22  ? 146.437 123.083 79.673  1.00 174.95 ?  22  ARG A O   1 
ATOM   6530 C CB  . ARG E 5 22  ? 146.067 121.527 81.091  1.00 174.95 ?  22  ARG A CB  1 
ATOM   6531 N N   . ASP E 5 23  ? 145.023 124.673 80.363  1.00 175.42 ?  23  ASP A N   1 
ATOM   6532 C CA  . ASP E 5 23  ? 145.600 125.713 79.474  1.00 175.42 ?  23  ASP A CA  1 
ATOM   6533 C C   . ASP E 5 23  ? 146.739 126.523 80.104  1.00 175.42 ?  23  ASP A C   1 
ATOM   6534 O O   . ASP E 5 23  ? 146.790 126.713 81.310  1.00 175.42 ?  23  ASP A O   1 
ATOM   6535 C CB  . ASP E 5 23  ? 144.301 126.522 79.623  1.00 175.42 ?  23  ASP A CB  1 
ATOM   6536 C CG  . ASP E 5 23  ? 144.500 127.993 79.305  1.00 175.42 ?  23  ASP A CG  1 
ATOM   6537 O OD1 . ASP E 5 23  ? 144.376 128.364 78.120  1.00 175.42 ?  23  ASP A OD1 1 
ATOM   6538 O OD2 . ASP E 5 23  ? 144.792 128.777 80.236  1.00 175.42 -1 23  ASP A OD2 1 
ATOM   6539 N N   . ASP E 5 24  ? 147.632 127.040 79.280  1.00 175.19 ?  24  ASP A N   1 
ATOM   6540 C CA  . ASP E 5 24  ? 148.678 127.944 79.746  1.00 175.19 ?  24  ASP A CA  1 
ATOM   6541 C C   . ASP E 5 24  ? 148.521 129.386 80.218  1.00 175.19 ?  24  ASP A C   1 
ATOM   6542 O O   . ASP E 5 24  ? 149.386 129.910 80.928  1.00 175.19 ?  24  ASP A O   1 
ATOM   6543 C CB  . ASP E 5 24  ? 149.627 127.885 78.547  1.00 175.19 ?  24  ASP A CB  1 
ATOM   6544 N N   . PHE E 5 25  ? 147.424 130.035 79.819  1.00 174.17 ?  25  PHE A N   1 
ATOM   6545 C CA  . PHE E 5 25  ? 147.157 131.403 80.258  1.00 174.17 ?  25  PHE A CA  1 
ATOM   6546 C C   . PHE E 5 25  ? 147.001 131.463 81.772  1.00 174.17 ?  25  PHE A C   1 
ATOM   6547 O O   . PHE E 5 25  ? 147.516 132.380 82.429  1.00 174.17 ?  25  PHE A O   1 
ATOM   6548 C CB  . PHE E 5 25  ? 145.906 131.925 79.540  1.00 174.17 ?  25  PHE A CB  1 
ATOM   6549 N N   . ILE E 5 26  ? 146.305 130.479 82.345  1.00 171.80 ?  26  ILE A N   1 
ATOM   6550 C CA  . ILE E 5 26  ? 146.156 130.419 83.796  1.00 171.80 ?  26  ILE A CA  1 
ATOM   6551 C C   . ILE E 5 26  ? 147.523 130.257 84.452  1.00 171.80 ?  26  ILE A C   1 
ATOM   6552 O O   . ILE E 5 26  ? 147.843 130.929 85.438  1.00 171.80 ?  26  ILE A O   1 
ATOM   6553 C CB  . ILE E 5 26  ? 145.179 129.295 84.196  1.00 171.80 ?  26  ILE A CB  1 
ATOM   6554 C CG1 . ILE E 5 26  ? 144.773 129.432 85.664  1.00 171.80 ?  26  ILE A CG1 1 
ATOM   6555 C CG2 . ILE E 5 26  ? 145.734 127.904 83.885  1.00 171.80 ?  26  ILE A CG2 1 
ATOM   6556 C CD1 . ILE E 5 26  ? 143.955 130.674 85.944  1.00 171.80 ?  26  ILE A CD1 1 
ATOM   6557 N N   . ALA E 5 27  ? 148.375 129.408 83.869  1.00 173.40 ?  27  ALA A N   1 
ATOM   6558 C CA  . ALA E 5 27  ? 149.685 129.146 84.455  1.00 173.40 ?  27  ALA A CA  1 
ATOM   6559 C C   . ALA E 5 27  ? 150.569 130.385 84.455  1.00 173.40 ?  27  ALA A C   1 
ATOM   6560 O O   . ALA E 5 27  ? 151.525 130.465 85.235  1.00 173.40 ?  27  ALA A O   1 
ATOM   6561 C CB  . ALA E 5 27  ? 150.375 128.006 83.705  1.00 173.40 ?  27  ALA A CB  1 
ATOM   6562 N N   . LYS E 5 28  ? 150.276 131.359 83.593  1.00 173.71 ?  28  LYS A N   1 
ATOM   6563 C CA  . LYS E 5 28  ? 151.086 132.566 83.525  1.00 173.71 ?  28  LYS A CA  1 
ATOM   6564 C C   . LYS E 5 28  ? 150.449 133.773 84.200  1.00 173.71 ?  28  LYS A C   1 
ATOM   6565 O O   . LYS E 5 28  ? 151.149 134.765 84.430  1.00 173.71 ?  28  LYS A O   1 
ATOM   6566 C CB  . LYS E 5 28  ? 151.407 132.921 82.066  1.00 173.71 ?  28  LYS A CB  1 
ATOM   6567 C CG  . LYS E 5 28  ? 150.213 133.364 81.241  1.00 173.71 ?  28  LYS A CG  1 
ATOM   6568 C CD  . LYS E 5 28  ? 150.639 133.848 79.864  1.00 173.71 ?  28  LYS A CD  1 
ATOM   6569 C CE  . LYS E 5 28  ? 151.236 132.721 79.036  1.00 173.71 ?  28  LYS A CE  1 
ATOM   6570 N NZ  . LYS E 5 28  ? 150.248 131.641 78.770  1.00 173.71 1  28  LYS A NZ  1 
ATOM   6571 N N   . VAL E 5 29  ? 149.155 133.729 84.527  1.00 172.41 ?  29  VAL A N   1 
ATOM   6572 C CA  . VAL E 5 29  ? 148.539 134.901 85.147  1.00 172.41 ?  29  VAL A CA  1 
ATOM   6573 C C   . VAL E 5 29  ? 148.105 134.639 86.587  1.00 172.41 ?  29  VAL A C   1 
ATOM   6574 O O   . VAL E 5 29  ? 147.989 135.577 87.383  1.00 172.41 ?  29  VAL A O   1 
ATOM   6575 C CB  . VAL E 5 29  ? 147.352 135.412 84.308  1.00 172.41 ?  29  VAL A CB  1 
ATOM   6576 C CG1 . VAL E 5 29  ? 147.784 135.623 82.867  1.00 172.41 ?  29  VAL A CG1 1 
ATOM   6577 C CG2 . VAL E 5 29  ? 146.170 134.456 84.397  1.00 172.41 ?  29  VAL A CG2 1 
ATOM   6578 N N   . LEU E 5 30  ? 147.862 133.378 86.940  1.00 168.77 ?  30  LEU A N   1 
ATOM   6579 C CA  . LEU E 5 30  ? 147.326 133.019 88.247  1.00 168.77 ?  30  LEU A CA  1 
ATOM   6580 C C   . LEU E 5 30  ? 148.381 132.964 89.354  1.00 168.77 ?  30  LEU A C   1 
ATOM   6581 O O   . LEU E 5 30  ? 148.099 133.408 90.478  1.00 168.77 ?  30  LEU A O   1 
ATOM   6582 C CB  . LEU E 5 30  ? 146.602 131.675 88.146  1.00 168.77 ?  30  LEU A CB  1 
ATOM   6583 N N   . PRO E 5 31  ? 149.575 132.413 89.110  1.00 168.31 ?  31  PRO A N   1 
ATOM   6584 C CA  . PRO E 5 31  ? 150.584 132.339 90.177  1.00 168.31 ?  31  PRO A CA  1 
ATOM   6585 C C   . PRO E 5 31  ? 150.896 133.694 90.791  1.00 168.31 ?  31  PRO A C   1 
ATOM   6586 O O   . PRO E 5 31  ? 151.113 133.765 92.007  1.00 168.31 ?  31  PRO A O   1 
ATOM   6587 C CB  . PRO E 5 31  ? 151.809 131.746 89.465  1.00 168.31 ?  31  PRO A CB  1 
ATOM   6588 C CG  . PRO E 5 31  ? 151.225 130.890 88.426  1.00 168.31 ?  31  PRO A CG  1 
ATOM   6589 C CD  . PRO E 5 31  ? 150.000 131.618 87.939  1.00 168.31 ?  31  PRO A CD  1 
ATOM   6590 N N   . PRO E 5 32  ? 150.956 134.791 90.016  1.00 167.78 ?  32  PRO A N   1 
ATOM   6591 C CA  . PRO E 5 32  ? 151.118 136.098 90.683  1.00 167.78 ?  32  PRO A CA  1 
ATOM   6592 C C   . PRO E 5 32  ? 150.007 136.416 91.671  1.00 167.78 ?  32  PRO A C   1 
ATOM   6593 O O   . PRO E 5 32  ? 150.283 136.913 92.771  1.00 167.78 ?  32  PRO A O   1 
ATOM   6594 C CB  . PRO E 5 32  ? 151.137 137.086 89.509  1.00 167.78 ?  32  PRO A CB  1 
ATOM   6595 C CG  . PRO E 5 32  ? 151.682 136.303 88.389  1.00 167.78 ?  32  PRO A CG  1 
ATOM   6596 C CD  . PRO E 5 32  ? 151.106 134.928 88.553  1.00 167.78 ?  32  PRO A CD  1 
ATOM   6597 N N   . VAL E 5 33  ? 148.755 136.115 91.319  1.00 164.83 ?  33  VAL A N   1 
ATOM   6598 C CA  . VAL E 5 33  ? 147.639 136.411 92.213  1.00 164.83 ?  33  VAL A CA  1 
ATOM   6599 C C   . VAL E 5 33  ? 147.719 135.551 93.468  1.00 164.83 ?  33  VAL A C   1 
ATOM   6600 O O   . VAL E 5 33  ? 147.533 136.039 94.590  1.00 164.83 ?  33  VAL A O   1 
ATOM   6601 C CB  . VAL E 5 33  ? 146.299 136.217 91.480  1.00 164.83 ?  33  VAL A CB  1 
ATOM   6602 C CG1 . VAL E 5 33  ? 145.136 136.526 92.409  1.00 164.83 ?  33  VAL A CG1 1 
ATOM   6603 C CG2 . VAL E 5 33  ? 146.244 137.091 90.237  1.00 164.83 ?  33  VAL A CG2 1 
ATOM   6604 N N   . LEU E 5 34  ? 147.998 134.257 93.299  1.00 162.08 ?  34  LEU A N   1 
ATOM   6605 C CA  . LEU E 5 34  ? 148.089 133.373 94.458  1.00 162.08 ?  34  LEU A CA  1 
ATOM   6606 C C   . LEU E 5 34  ? 149.280 133.736 95.338  1.00 162.08 ?  34  LEU A C   1 
ATOM   6607 O O   . LEU E 5 34  ? 149.206 133.637 96.569  1.00 162.08 ?  34  LEU A O   1 
ATOM   6608 C CB  . LEU E 5 34  ? 148.165 131.915 94.006  1.00 162.08 ?  34  LEU A CB  1 
ATOM   6609 C CG  . LEU E 5 34  ? 146.845 131.127 93.947  1.00 162.08 ?  34  LEU A CG  1 
ATOM   6610 C CD1 . LEU E 5 34  ? 146.293 130.787 95.328  1.00 162.08 ?  34  LEU A CD1 1 
ATOM   6611 C CD2 . LEU E 5 34  ? 145.786 131.898 93.175  1.00 162.08 ?  34  LEU A CD2 1 
ATOM   6612 N N   . GLY E 5 35  ? 150.385 134.169 94.729  1.00 162.43 ?  35  GLY A N   1 
ATOM   6613 C CA  . GLY E 5 35  ? 151.522 134.618 95.512  1.00 162.43 ?  35  GLY A CA  1 
ATOM   6614 C C   . GLY E 5 35  ? 151.226 135.882 96.291  1.00 162.43 ?  35  GLY A C   1 
ATOM   6615 O O   . GLY E 5 35  ? 151.653 136.029 97.437  1.00 162.43 ?  35  GLY A O   1 
ATOM   6616 N N   . LEU E 5 36  ? 150.487 136.814 95.682  1.00 161.78 ?  36  LEU A N   1 
ATOM   6617 C CA  . LEU E 5 36  ? 150.057 138.000 96.416  1.00 161.78 ?  36  LEU A CA  1 
ATOM   6618 C C   . LEU E 5 36  ? 149.149 137.621 97.579  1.00 161.78 ?  36  LEU A C   1 
ATOM   6619 O O   . LEU E 5 36  ? 149.262 138.181 98.677  1.00 161.78 ?  36  LEU A O   1 
ATOM   6620 C CB  . LEU E 5 36  ? 149.348 138.973 95.474  1.00 161.78 ?  36  LEU A CB  1 
ATOM   6621 C CG  . LEU E 5 36  ? 149.292 140.433 95.929  1.00 161.78 ?  36  LEU A CG  1 
ATOM   6622 C CD1 . LEU E 5 36  ? 150.614 141.133 95.651  1.00 161.78 ?  36  LEU A CD1 1 
ATOM   6623 C CD2 . LEU E 5 36  ? 148.141 141.164 95.255  1.00 161.78 ?  36  LEU A CD2 1 
ATOM   6624 N N   . GLU E 5 37  ? 148.243 136.665 97.354  1.00 158.33 ?  37  GLU A N   1 
ATOM   6625 C CA  . GLU E 5 37  ? 147.373 136.194 98.429  1.00 158.33 ?  37  GLU A CA  1 
ATOM   6626 C C   . GLU E 5 37  ? 148.190 135.606 99.573  1.00 158.33 ?  37  GLU A C   1 
ATOM   6627 O O   . GLU E 5 37  ? 147.950 135.912 100.746 1.00 158.33 ?  37  GLU A O   1 
ATOM   6628 C CB  . GLU E 5 37  ? 146.387 135.157 97.889  1.00 158.33 ?  37  GLU A CB  1 
ATOM   6629 C CG  . GLU E 5 37  ? 145.354 135.702 96.916  1.00 158.33 ?  37  GLU A CG  1 
ATOM   6630 C CD  . GLU E 5 37  ? 144.601 136.895 97.465  1.00 158.33 ?  37  GLU A CD  1 
ATOM   6631 O OE1 . GLU E 5 37  ? 143.762 136.704 98.370  1.00 158.33 ?  37  GLU A OE1 1 
ATOM   6632 O OE2 . GLU E 5 37  ? 144.843 138.023 96.987  1.00 158.33 -1 37  GLU A OE2 1 
ATOM   6633 N N   . PHE E 5 38  ? 149.172 134.762 99.246  1.00 159.81 ?  38  PHE A N   1 
ATOM   6634 C CA  . PHE E 5 38  ? 149.977 134.129 100.286 1.00 159.81 ?  38  PHE A CA  1 
ATOM   6635 C C   . PHE E 5 38  ? 150.898 135.129 100.974 1.00 159.81 ?  38  PHE A C   1 
ATOM   6636 O O   . PHE E 5 38  ? 151.268 134.934 102.136 1.00 159.81 ?  38  PHE A O   1 
ATOM   6637 C CB  . PHE E 5 38  ? 150.789 132.976 99.696  1.00 159.81 ?  38  PHE A CB  1 
ATOM   6638 C CG  . PHE E 5 38  ? 151.617 132.237 100.709 1.00 159.81 ?  38  PHE A CG  1 
ATOM   6639 C CD1 . PHE E 5 38  ? 151.023 131.348 101.589 1.00 159.81 ?  38  PHE A CD1 1 
ATOM   6640 C CD2 . PHE E 5 38  ? 152.986 132.432 100.782 1.00 159.81 ?  38  PHE A CD2 1 
ATOM   6641 C CE1 . PHE E 5 38  ? 151.779 130.666 102.524 1.00 159.81 ?  38  PHE A CE1 1 
ATOM   6642 C CE2 . PHE E 5 38  ? 153.747 131.752 101.715 1.00 159.81 ?  38  PHE A CE2 1 
ATOM   6643 C CZ  . PHE E 5 38  ? 153.142 130.869 102.587 1.00 159.81 ?  38  PHE A CZ  1 
ATOM   6644 N N   . ILE E 5 39  ? 151.298 136.189 100.273 1.00 161.51 ?  39  ILE A N   1 
ATOM   6645 C CA  . ILE E 5 39  ? 152.109 137.225 100.901 1.00 161.51 ?  39  ILE A CA  1 
ATOM   6646 C C   . ILE E 5 39  ? 151.273 138.035 101.883 1.00 161.51 ?  39  ILE A C   1 
ATOM   6647 O O   . ILE E 5 39  ? 151.712 138.321 103.004 1.00 161.51 ?  39  ILE A O   1 
ATOM   6648 C CB  . ILE E 5 39  ? 152.755 138.118 99.826  1.00 161.51 ?  39  ILE A CB  1 
ATOM   6649 C CG1 . ILE E 5 39  ? 153.980 137.425 99.226  1.00 161.51 ?  39  ILE A CG1 1 
ATOM   6650 C CG2 . ILE E 5 39  ? 153.138 139.472 100.405 1.00 161.51 ?  39  ILE A CG2 1 
ATOM   6651 C CD1 . ILE E 5 39  ? 154.593 138.169 98.060  1.00 161.51 ?  39  ILE A CD1 1 
ATOM   6652 N N   . PHE E 5 40  ? 150.053 138.403 101.491 1.00 158.34 ?  40  PHE A N   1 
ATOM   6653 C CA  . PHE E 5 40  ? 149.258 139.333 102.288 1.00 158.34 ?  40  PHE A CA  1 
ATOM   6654 C C   . PHE E 5 40  ? 148.444 138.630 103.374 1.00 158.34 ?  40  PHE A C   1 
ATOM   6655 O O   . PHE E 5 40  ? 148.611 138.918 104.563 1.00 158.34 ?  40  PHE A O   1 
ATOM   6656 C CB  . PHE E 5 40  ? 148.342 140.150 101.372 1.00 158.34 ?  40  PHE A CB  1 
ATOM   6657 C CG  . PHE E 5 40  ? 148.987 141.393 100.828 1.00 158.34 ?  40  PHE A CG  1 
ATOM   6658 C CD1 . PHE E 5 40  ? 149.207 142.488 101.646 1.00 158.34 ?  40  PHE A CD1 1 
ATOM   6659 C CD2 . PHE E 5 40  ? 149.376 141.463 99.501  1.00 158.34 ?  40  PHE A CD2 1 
ATOM   6660 C CE1 . PHE E 5 40  ? 149.802 143.632 101.150 1.00 158.34 ?  40  PHE A CE1 1 
ATOM   6661 C CE2 . PHE E 5 40  ? 149.971 142.605 98.999  1.00 158.34 ?  40  PHE A CE2 1 
ATOM   6662 C CZ  . PHE E 5 40  ? 150.185 143.691 99.825  1.00 158.34 ?  40  PHE A CZ  1 
ATOM   6663 N N   . GLY E 5 41  ? 147.564 137.709 102.986 1.00 153.74 ?  41  GLY A N   1 
ATOM   6664 C CA  . GLY E 5 41  ? 146.632 137.134 103.936 1.00 153.74 ?  41  GLY A CA  1 
ATOM   6665 C C   . GLY E 5 41  ? 147.200 136.040 104.816 1.00 153.74 ?  41  GLY A C   1 
ATOM   6666 O O   . GLY E 5 41  ? 146.541 135.025 105.049 1.00 153.74 ?  41  GLY A O   1 
ATOM   6667 N N   . LEU E 5 42  ? 148.425 136.231 105.302 1.00 152.02 ?  42  LEU A N   1 
ATOM   6668 C CA  . LEU E 5 42  ? 149.059 135.350 106.277 1.00 152.02 ?  42  LEU A CA  1 
ATOM   6669 C C   . LEU E 5 42  ? 149.430 136.074 107.561 1.00 152.02 ?  42  LEU A C   1 
ATOM   6670 O O   . LEU E 5 42  ? 149.135 135.576 108.656 1.00 152.02 ?  42  LEU A O   1 
ATOM   6671 C CB  . LEU E 5 42  ? 150.306 134.686 105.664 1.00 152.02 ?  42  LEU A CB  1 
ATOM   6672 C CG  . LEU E 5 42  ? 150.195 133.373 104.880 1.00 152.02 ?  42  LEU A CG  1 
ATOM   6673 C CD1 . LEU E 5 42  ? 149.804 132.249 105.813 1.00 152.02 ?  42  LEU A CD1 1 
ATOM   6674 C CD2 . LEU E 5 42  ? 149.166 133.469 103.769 1.00 152.02 ?  42  LEU A CD2 1 
ATOM   6675 N N   . LEU E 5 43  ? 150.071 137.240 107.455 1.00 152.21 ?  43  LEU A N   1 
ATOM   6676 C CA  . LEU E 5 43  ? 150.482 137.972 108.648 1.00 152.21 ?  43  LEU A CA  1 
ATOM   6677 C C   . LEU E 5 43  ? 149.278 138.438 109.456 1.00 152.21 ?  43  LEU A C   1 
ATOM   6678 O O   . LEU E 5 43  ? 149.308 138.412 110.692 1.00 152.21 ?  43  LEU A O   1 
ATOM   6679 C CB  . LEU E 5 43  ? 151.385 139.147 108.256 1.00 152.21 ?  43  LEU A CB  1 
ATOM   6680 C CG  . LEU E 5 43  ? 150.890 140.279 107.344 1.00 152.21 ?  43  LEU A CG  1 
ATOM   6681 C CD1 . LEU E 5 43  ? 150.137 141.363 108.109 1.00 152.21 ?  43  LEU A CD1 1 
ATOM   6682 C CD2 . LEU E 5 43  ? 152.054 140.880 106.569 1.00 152.21 ?  43  LEU A CD2 1 
ATOM   6683 N N   . GLY E 5 44  ? 148.207 138.862 108.781 1.00 147.29 ?  44  GLY A N   1 
ATOM   6684 C CA  . GLY E 5 44  ? 147.023 139.302 109.500 1.00 147.29 ?  44  GLY A CA  1 
ATOM   6685 C C   . GLY E 5 44  ? 146.378 138.183 110.295 1.00 147.29 ?  44  GLY A C   1 
ATOM   6686 O O   . GLY E 5 44  ? 146.029 138.355 111.466 1.00 147.29 ?  44  GLY A O   1 
ATOM   6687 N N   . ASN E 5 45  ? 146.218 137.016 109.668 1.00 145.55 ?  45  ASN A N   1 
ATOM   6688 C CA  . ASN E 5 45  ? 145.653 135.870 110.372 1.00 145.55 ?  45  ASN A CA  1 
ATOM   6689 C C   . ASN E 5 45  ? 146.558 135.414 111.508 1.00 145.55 ?  45  ASN A C   1 
ATOM   6690 O O   . ASN E 5 45  ? 146.071 135.057 112.587 1.00 145.55 ?  45  ASN A O   1 
ATOM   6691 C CB  . ASN E 5 45  ? 145.395 134.725 109.394 1.00 145.55 ?  45  ASN A CB  1 
ATOM   6692 C CG  . ASN E 5 45  ? 144.357 135.076 108.348 1.00 145.55 ?  45  ASN A CG  1 
ATOM   6693 O OD1 . ASN E 5 45  ? 143.120 135.266 108.787 1.00 145.55 ?  45  ASN A OD1 1 
ATOM   6694 N ND2 . ASN E 5 45  ? 144.659 135.160 107.158 1.00 145.55 ?  45  ASN A ND2 1 
ATOM   6695 N N   . GLY E 5 46  ? 147.875 135.414 111.290 1.00 147.22 ?  46  GLY A N   1 
ATOM   6696 C CA  . GLY E 5 46  ? 148.783 135.047 112.364 1.00 147.22 ?  46  GLY A CA  1 
ATOM   6697 C C   . GLY E 5 46  ? 148.698 135.994 113.545 1.00 147.22 ?  46  GLY A C   1 
ATOM   6698 O O   . GLY E 5 46  ? 148.667 135.562 114.701 1.00 147.22 ?  46  GLY A O   1 
ATOM   6699 N N   . LEU E 5 47  ? 148.647 137.300 113.270 1.00 146.00 ?  47  LEU A N   1 
ATOM   6700 C CA  . LEU E 5 47  ? 148.516 138.281 114.341 1.00 146.00 ?  47  LEU A CA  1 
ATOM   6701 C C   . LEU E 5 47  ? 147.193 138.120 115.076 1.00 146.00 ?  47  LEU A C   1 
ATOM   6702 O O   . LEU E 5 47  ? 147.142 138.222 116.307 1.00 146.00 ?  47  LEU A O   1 
ATOM   6703 C CB  . LEU E 5 47  ? 148.649 139.694 113.772 1.00 146.00 ?  47  LEU A CB  1 
ATOM   6704 C CG  . LEU E 5 47  ? 148.343 140.856 114.719 1.00 146.00 ?  47  LEU A CG  1 
ATOM   6705 C CD1 . LEU E 5 47  ? 149.276 140.830 115.919 1.00 146.00 ?  47  LEU A CD1 1 
ATOM   6706 C CD2 . LEU E 5 47  ? 148.443 142.185 113.987 1.00 146.00 ?  47  LEU A CD2 1 
ATOM   6707 N N   . ALA E 5 48  ? 146.108 137.869 114.337 1.00 144.30 ?  48  ALA A N   1 
ATOM   6708 C CA  . ALA E 5 48  ? 144.811 137.668 114.976 1.00 144.30 ?  48  ALA A CA  1 
ATOM   6709 C C   . ALA E 5 48  ? 144.821 136.437 115.873 1.00 144.30 ?  48  ALA A C   1 
ATOM   6710 O O   . ALA E 5 48  ? 144.303 136.475 116.996 1.00 144.30 ?  48  ALA A O   1 
ATOM   6711 C CB  . ALA E 5 48  ? 143.716 137.553 113.916 1.00 144.30 ?  48  ALA A CB  1 
ATOM   6712 N N   . LEU E 5 49  ? 145.409 135.337 115.397 1.00 144.71 ?  49  LEU A N   1 
ATOM   6713 C CA  . LEU E 5 49  ? 145.498 134.131 116.214 1.00 144.71 ?  49  LEU A CA  1 
ATOM   6714 C C   . LEU E 5 49  ? 146.341 134.369 117.461 1.00 144.71 ?  49  LEU A C   1 
ATOM   6715 O O   . LEU E 5 49  ? 145.979 133.926 118.557 1.00 144.71 ?  49  LEU A O   1 
ATOM   6716 C CB  . LEU E 5 49  ? 146.073 132.977 115.392 1.00 144.71 ?  49  LEU A CB  1 
ATOM   6717 C CG  . LEU E 5 49  ? 145.089 132.019 114.715 1.00 144.71 ?  49  LEU A CG  1 
ATOM   6718 C CD1 . LEU E 5 49  ? 144.266 131.278 115.756 1.00 144.71 ?  49  LEU A CD1 1 
ATOM   6719 C CD2 . LEU E 5 49  ? 144.187 132.746 113.734 1.00 144.71 ?  49  LEU A CD2 1 
ATOM   6720 N N   . TRP E 5 50  ? 147.471 135.066 117.312 1.00 148.19 ?  50  TRP A N   1 
ATOM   6721 C CA  . TRP E 5 50  ? 148.322 135.344 118.464 1.00 148.19 ?  50  TRP A CA  1 
ATOM   6722 C C   . TRP E 5 50  ? 147.607 136.224 119.482 1.00 148.19 ?  50  TRP A C   1 
ATOM   6723 O O   . TRP E 5 50  ? 147.719 136.001 120.693 1.00 148.19 ?  50  TRP A O   1 
ATOM   6724 C CB  . TRP E 5 50  ? 149.626 135.998 118.006 1.00 148.19 ?  50  TRP A CB  1 
ATOM   6725 C CG  . TRP E 5 50  ? 150.464 135.110 117.135 1.00 148.19 ?  50  TRP A CG  1 
ATOM   6726 C CD1 . TRP E 5 50  ? 150.457 133.745 117.110 1.00 148.19 ?  50  TRP A CD1 1 
ATOM   6727 C CD2 . TRP E 5 50  ? 151.427 135.524 116.159 1.00 148.19 ?  50  TRP A CD2 1 
ATOM   6728 N NE1 . TRP E 5 50  ? 151.358 133.284 116.181 1.00 148.19 ?  50  TRP A NE1 1 
ATOM   6729 C CE2 . TRP E 5 50  ? 151.967 134.356 115.583 1.00 148.19 ?  50  TRP A CE2 1 
ATOM   6730 C CE3 . TRP E 5 50  ? 151.887 136.768 115.716 1.00 148.19 ?  50  TRP A CE3 1 
ATOM   6731 C CZ2 . TRP E 5 50  ? 152.942 134.395 114.588 1.00 148.19 ?  50  TRP A CZ2 1 
ATOM   6732 C CZ3 . TRP E 5 50  ? 152.855 136.805 114.728 1.00 148.19 ?  50  TRP A CZ3 1 
ATOM   6733 C CH2 . TRP E 5 50  ? 153.372 135.626 114.176 1.00 148.19 ?  50  TRP A CH2 1 
ATOM   6734 N N   . ILE E 5 51  ? 146.870 137.233 119.010 1.00 143.75 ?  51  ILE A N   1 
ATOM   6735 C CA  . ILE E 5 51  ? 146.139 138.109 119.921 1.00 143.75 ?  51  ILE A CA  1 
ATOM   6736 C C   . ILE E 5 51  ? 145.039 137.338 120.639 1.00 143.75 ?  51  ILE A C   1 
ATOM   6737 O O   . ILE E 5 51  ? 144.843 137.489 121.851 1.00 143.75 ?  51  ILE A O   1 
ATOM   6738 C CB  . ILE E 5 51  ? 145.581 139.327 119.160 1.00 143.75 ?  51  ILE A CB  1 
ATOM   6739 C CG1 . ILE E 5 51  ? 146.717 140.274 118.770 1.00 143.75 ?  51  ILE A CG1 1 
ATOM   6740 C CG2 . ILE E 5 51  ? 144.552 140.061 120.003 1.00 143.75 ?  51  ILE A CG2 1 
ATOM   6741 C CD1 . ILE E 5 51  ? 146.266 141.466 117.959 1.00 143.75 ?  51  ILE A CD1 1 
ATOM   6742 N N   . PHE E 5 52  ? 144.304 136.497 119.905 1.00 140.79 ?  52  PHE A N   1 
ATOM   6743 C CA  . PHE E 5 52  ? 143.237 135.716 120.523 1.00 140.79 ?  52  PHE A CA  1 
ATOM   6744 C C   . PHE E 5 52  ? 143.786 134.747 121.562 1.00 140.79 ?  52  PHE A C   1 
ATOM   6745 O O   . PHE E 5 52  ? 143.208 134.592 122.644 1.00 140.79 ?  52  PHE A O   1 
ATOM   6746 C CB  . PHE E 5 52  ? 142.452 134.960 119.451 1.00 140.79 ?  52  PHE A CB  1 
ATOM   6747 C CG  . PHE E 5 52  ? 141.403 135.788 118.767 1.00 140.79 ?  52  PHE A CG  1 
ATOM   6748 C CD1 . PHE E 5 52  ? 140.867 136.903 119.388 1.00 140.79 ?  52  PHE A CD1 1 
ATOM   6749 C CD2 . PHE E 5 52  ? 140.953 135.451 117.502 1.00 140.79 ?  52  PHE A CD2 1 
ATOM   6750 C CE1 . PHE E 5 52  ? 139.902 137.666 118.761 1.00 140.79 ?  52  PHE A CE1 1 
ATOM   6751 C CE2 . PHE E 5 52  ? 139.988 136.211 116.870 1.00 140.79 ?  52  PHE A CE2 1 
ATOM   6752 C CZ  . PHE E 5 52  ? 139.462 137.320 117.501 1.00 140.79 ?  52  PHE A CZ  1 
ATOM   6753 N N   . CYS E 5 53  ? 144.904 134.086 121.254 1.00 144.91 ?  53  CYS A N   1 
ATOM   6754 C CA  . CYS E 5 53  ? 145.415 133.043 122.136 1.00 144.91 ?  53  CYS A CA  1 
ATOM   6755 C C   . CYS E 5 53  ? 145.935 133.620 123.449 1.00 144.91 ?  53  CYS A C   1 
ATOM   6756 O O   . CYS E 5 53  ? 145.630 133.100 124.529 1.00 144.91 ?  53  CYS A O   1 
ATOM   6757 C CB  . CYS E 5 53  ? 146.512 132.249 121.425 1.00 144.91 ?  53  CYS A CB  1 
ATOM   6758 S SG  . CYS E 5 53  ? 145.906 131.110 120.158 1.00 144.91 ?  53  CYS A SG  1 
ATOM   6759 N N   . PHE E 5 54  ? 146.720 134.694 123.380 1.00 146.45 ?  54  PHE A N   1 
ATOM   6760 C CA  . PHE E 5 54  ? 147.415 135.207 124.555 1.00 146.45 ?  54  PHE A CA  1 
ATOM   6761 C C   . PHE E 5 54  ? 147.021 136.631 124.915 1.00 146.45 ?  54  PHE A C   1 
ATOM   6762 O O   . PHE E 5 54  ? 146.746 136.912 126.088 1.00 146.45 ?  54  PHE A O   1 
ATOM   6763 C CB  . PHE E 5 54  ? 148.935 135.128 124.336 1.00 146.45 ?  54  PHE A CB  1 
ATOM   6764 C CG  . PHE E 5 54  ? 149.404 133.794 123.831 1.00 146.45 ?  54  PHE A CG  1 
ATOM   6765 C CD1 . PHE E 5 54  ? 149.365 132.676 124.647 1.00 146.45 ?  54  PHE A CD1 1 
ATOM   6766 C CD2 . PHE E 5 54  ? 149.885 133.658 122.539 1.00 146.45 ?  54  PHE A CD2 1 
ATOM   6767 C CE1 . PHE E 5 54  ? 149.796 131.447 124.185 1.00 146.45 ?  54  PHE A CE1 1 
ATOM   6768 C CE2 . PHE E 5 54  ? 150.318 132.432 122.071 1.00 146.45 ?  54  PHE A CE2 1 
ATOM   6769 C CZ  . PHE E 5 54  ? 150.273 131.325 122.895 1.00 146.45 ?  54  PHE A CZ  1 
ATOM   6770 N N   . HIS E 5 55  ? 146.995 137.544 123.940 1.00 145.48 ?  55  HIS A N   1 
ATOM   6771 C CA  . HIS E 5 55  ? 146.777 138.954 124.250 1.00 145.48 ?  55  HIS A CA  1 
ATOM   6772 C C   . HIS E 5 55  ? 145.397 139.194 124.853 1.00 145.48 ?  55  HIS A C   1 
ATOM   6773 O O   . HIS E 5 55  ? 145.258 139.959 125.815 1.00 145.48 ?  55  HIS A O   1 
ATOM   6774 C CB  . HIS E 5 55  ? 146.965 139.803 122.993 1.00 145.48 ?  55  HIS A CB  1 
ATOM   6775 C CG  . HIS E 5 55  ? 148.392 139.939 122.563 1.00 145.48 ?  55  HIS A CG  1 
ATOM   6776 N ND1 . HIS E 5 55  ? 148.956 139.142 121.590 1.00 145.48 ?  55  HIS A ND1 1 
ATOM   6777 C CD2 . HIS E 5 55  ? 149.370 140.781 122.971 1.00 145.48 ?  55  HIS A CD2 1 
ATOM   6778 C CE1 . HIS E 5 55  ? 150.220 139.486 121.419 1.00 145.48 ?  55  HIS A CE1 1 
ATOM   6779 N NE2 . HIS E 5 55  ? 150.496 140.479 122.245 1.00 145.48 ?  55  HIS A NE2 1 
ATOM   6780 N N   . LEU E 5 56  ? 144.368 138.553 124.307 1.00 142.60 ?  56  LEU A N   1 
ATOM   6781 C CA  . LEU E 5 56  ? 143.002 138.762 124.767 1.00 142.60 ?  56  LEU A CA  1 
ATOM   6782 C C   . LEU E 5 56  ? 142.636 137.725 125.820 1.00 142.60 ?  56  LEU A C   1 
ATOM   6783 O O   . LEU E 5 56  ? 142.788 136.519 125.595 1.00 142.60 ?  56  LEU A O   1 
ATOM   6784 C CB  . LEU E 5 56  ? 142.021 138.696 123.596 1.00 142.60 ?  56  LEU A CB  1 
ATOM   6785 C CG  . LEU E 5 56  ? 141.957 139.943 122.713 1.00 142.60 ?  56  LEU A CG  1 
ATOM   6786 C CD1 . LEU E 5 56  ? 140.975 139.747 121.570 1.00 142.60 ?  56  LEU A CD1 1 
ATOM   6787 C CD2 . LEU E 5 56  ? 141.587 141.165 123.539 1.00 142.60 ?  56  LEU A CD2 1 
ATOM   6788 N N   . LYS E 5 57  ? 142.155 138.200 126.968 1.00 138.10 ?  57  LYS A N   1 
ATOM   6789 C CA  . LYS E 5 57  ? 141.725 137.339 128.063 1.00 138.10 ?  57  LYS A CA  1 
ATOM   6790 C C   . LYS E 5 57  ? 140.213 137.182 128.133 1.00 138.10 ?  57  LYS A C   1 
ATOM   6791 O O   . LYS E 5 57  ? 139.721 136.081 128.395 1.00 138.10 ?  57  LYS A O   1 
ATOM   6792 C CB  . LYS E 5 57  ? 142.244 137.888 129.397 1.00 138.10 ?  57  LYS A CB  1 
ATOM   6793 N N   . SER E 5 58  ? 139.464 138.257 127.895 1.00 136.94 ?  58  SER A N   1 
ATOM   6794 C CA  . SER E 5 58  ? 138.008 138.199 127.932 1.00 136.94 ?  58  SER A CA  1 
ATOM   6795 C C   . SER E 5 58  ? 137.493 137.517 126.671 1.00 136.94 ?  58  SER A C   1 
ATOM   6796 O O   . SER E 5 58  ? 137.702 138.014 125.559 1.00 136.94 ?  58  SER A O   1 
ATOM   6797 C CB  . SER E 5 58  ? 137.423 139.603 128.066 1.00 136.94 ?  58  SER A CB  1 
ATOM   6798 O OG  . SER E 5 58  ? 136.006 139.566 128.075 1.00 136.94 ?  58  SER A OG  1 
ATOM   6799 N N   . TRP E 5 59  ? 136.822 136.382 126.843 1.00 131.10 ?  59  TRP A N   1 
ATOM   6800 C CA  . TRP E 5 59  ? 136.292 135.598 125.736 1.00 131.10 ?  59  TRP A CA  1 
ATOM   6801 C C   . TRP E 5 59  ? 134.773 135.578 125.815 1.00 131.10 ?  59  TRP A C   1 
ATOM   6802 O O   . TRP E 5 59  ? 134.206 135.291 126.875 1.00 131.10 ?  59  TRP A O   1 
ATOM   6803 C CB  . TRP E 5 59  ? 136.847 134.172 125.759 1.00 131.10 ?  59  TRP A CB  1 
ATOM   6804 C CG  . TRP E 5 59  ? 138.183 134.041 125.099 1.00 131.10 ?  59  TRP A CG  1 
ATOM   6805 C CD1 . TRP E 5 59  ? 139.391 134.416 125.610 1.00 131.10 ?  59  TRP A CD1 1 
ATOM   6806 C CD2 . TRP E 5 59  ? 138.450 133.492 123.803 1.00 131.10 ?  59  TRP A CD2 1 
ATOM   6807 N NE1 . TRP E 5 59  ? 140.393 134.137 124.713 1.00 131.10 ?  59  TRP A NE1 1 
ATOM   6808 C CE2 . TRP E 5 59  ? 139.841 133.569 123.595 1.00 131.10 ?  59  TRP A CE2 1 
ATOM   6809 C CE3 . TRP E 5 59  ? 137.648 132.943 122.798 1.00 131.10 ?  59  TRP A CE3 1 
ATOM   6810 C CZ2 . TRP E 5 59  ? 140.447 133.118 122.424 1.00 131.10 ?  59  TRP A CZ2 1 
ATOM   6811 C CZ3 . TRP E 5 59  ? 138.251 132.496 121.637 1.00 131.10 ?  59  TRP A CZ3 1 
ATOM   6812 C CH2 . TRP E 5 59  ? 139.637 132.587 121.460 1.00 131.10 ?  59  TRP A CH2 1 
ATOM   6813 N N   . LYS E 5 60  ? 134.133 135.885 124.686 1.00 122.28 ?  60  LYS A N   1 
ATOM   6814 C CA  . LYS E 5 60  ? 132.678 135.869 124.620 1.00 122.28 ?  60  LYS A CA  1 
ATOM   6815 C C   . LYS E 5 60  ? 132.215 135.105 123.391 1.00 122.28 ?  60  LYS A C   1 
ATOM   6816 O O   . LYS E 5 60  ? 133.017 134.797 122.515 1.00 122.28 ?  60  LYS A O   1 
ATOM   6817 C CB  . LYS E 5 60  ? 132.126 137.287 124.625 1.00 122.28 ?  60  LYS A CB  1 
ATOM   6818 C CG  . LYS E 5 60  ? 131.810 137.810 126.013 1.00 122.28 ?  60  LYS A CG  1 
ATOM   6819 C CD  . LYS E 5 60  ? 132.928 138.697 126.529 1.00 122.28 ?  60  LYS A CD  1 
ATOM   6820 C CE  . LYS E 5 60  ? 132.370 139.943 127.195 1.00 122.28 ?  60  LYS A CE  1 
ATOM   6821 N NZ  . LYS E 5 60  ? 131.156 139.636 128.000 1.00 122.28 1  60  LYS A NZ  1 
ATOM   6822 N N   . SER E 5 61  ? 130.928 134.829 123.296 1.00 117.84 ?  61  SER A N   1 
ATOM   6823 C CA  . SER E 5 61  ? 130.396 133.993 122.223 1.00 117.84 ?  61  SER A CA  1 
ATOM   6824 C C   . SER E 5 61  ? 130.746 134.566 120.855 1.00 117.84 ?  61  SER A C   1 
ATOM   6825 O O   . SER E 5 61  ? 131.168 133.835 119.950 1.00 117.84 ?  61  SER A O   1 
ATOM   6826 C CB  . SER E 5 61  ? 128.883 133.847 122.380 1.00 117.84 ?  61  SER A CB  1 
ATOM   6827 O OG  . SER E 5 61  ? 128.295 133.320 121.205 1.00 117.84 ?  61  SER A OG  1 
ATOM   6828 N N   . SER E 5 62  ? 130.578 135.880 120.686 1.00 116.26 ?  62  SER A N   1 
ATOM   6829 C CA  . SER E 5 62  ? 130.973 136.517 119.435 1.00 116.26 ?  62  SER A CA  1 
ATOM   6830 C C   . SER E 5 62  ? 132.474 136.390 119.211 1.00 116.26 ?  62  SER A C   1 
ATOM   6831 O O   . SER E 5 62  ? 132.923 136.122 118.090 1.00 116.26 ?  62  SER A O   1 
ATOM   6832 C CB  . SER E 5 62  ? 130.550 137.985 119.436 1.00 116.26 ?  62  SER A CB  1 
ATOM   6833 O OG  . SER E 5 62  ? 131.259 138.717 120.421 1.00 116.26 ?  62  SER A OG  1 
ATOM   6834 N N   . ARG E 5 63  ? 133.263 136.572 120.272 1.00 120.70 ?  63  ARG A N   1 
ATOM   6835 C CA  . ARG E 5 63  ? 134.706 136.387 120.162 1.00 120.70 ?  63  ARG A CA  1 
ATOM   6836 C C   . ARG E 5 63  ? 135.048 134.947 119.804 1.00 120.70 ?  63  ARG A C   1 
ATOM   6837 O O   . ARG E 5 63  ? 135.980 134.698 119.032 1.00 120.70 ?  63  ARG A O   1 
ATOM   6838 C CB  . ARG E 5 63  ? 135.388 136.793 121.468 1.00 120.70 ?  63  ARG A CB  1 
ATOM   6839 C CG  . ARG E 5 63  ? 135.416 138.292 121.715 1.00 120.70 ?  63  ARG A CG  1 
ATOM   6840 C CD  . ARG E 5 63  ? 136.311 138.999 120.710 1.00 120.70 ?  63  ARG A CD  1 
ATOM   6841 N NE  . ARG E 5 63  ? 136.149 140.447 120.758 1.00 120.70 ?  63  ARG A NE  1 
ATOM   6842 C CZ  . ARG E 5 63  ? 136.482 141.271 119.773 1.00 120.70 ?  63  ARG A CZ  1 
ATOM   6843 N NH1 . ARG E 5 63  ? 137.001 140.822 118.642 1.00 120.70 1  63  ARG A NH1 1 
ATOM   6844 N NH2 . ARG E 5 63  ? 136.290 142.578 119.928 1.00 120.70 1  63  ARG A NH2 1 
ATOM   6845 N N   . ILE E 5 64  ? 134.303 133.985 120.352 1.00 119.16 ?  64  ILE A N   1 
ATOM   6846 C CA  . ILE E 5 64  ? 134.550 132.580 120.037 1.00 119.16 ?  64  ILE A CA  1 
ATOM   6847 C C   . ILE E 5 64  ? 134.271 132.307 118.562 1.00 119.16 ?  64  ILE A C   1 
ATOM   6848 O O   . ILE E 5 64  ? 135.055 131.638 117.878 1.00 119.16 ?  64  ILE A O   1 
ATOM   6849 C CB  . ILE E 5 64  ? 133.713 131.670 120.954 1.00 119.16 ?  64  ILE A CB  1 
ATOM   6850 C CG1 . ILE E 5 64  ? 134.379 131.550 122.325 1.00 119.16 ?  64  ILE A CG1 1 
ATOM   6851 C CG2 . ILE E 5 64  ? 133.528 130.297 120.329 1.00 119.16 ?  64  ILE A CG2 1 
ATOM   6852 C CD1 . ILE E 5 64  ? 133.602 130.718 123.315 1.00 119.16 ?  64  ILE A CD1 1 
ATOM   6853 N N   . PHE E 5 65  ? 133.151 132.824 118.050 1.00 116.27 ?  65  PHE A N   1 
ATOM   6854 C CA  . PHE E 5 65  ? 132.833 132.633 116.637 1.00 116.27 ?  65  PHE A CA  1 
ATOM   6855 C C   . PHE E 5 65  ? 133.874 133.297 115.743 1.00 116.27 ?  65  PHE A C   1 
ATOM   6856 O O   . PHE E 5 65  ? 134.263 132.742 114.706 1.00 116.27 ?  65  PHE A O   1 
ATOM   6857 C CB  . PHE E 5 65  ? 131.438 133.177 116.332 1.00 116.27 ?  65  PHE A CB  1 
ATOM   6858 C CG  . PHE E 5 65  ? 130.334 132.433 117.025 1.00 116.27 ?  65  PHE A CG  1 
ATOM   6859 C CD1 . PHE E 5 65  ? 130.380 131.055 117.145 1.00 116.27 ?  65  PHE A CD1 1 
ATOM   6860 C CD2 . PHE E 5 65  ? 129.248 133.110 117.552 1.00 116.27 ?  65  PHE A CD2 1 
ATOM   6861 C CE1 . PHE E 5 65  ? 129.365 130.368 117.781 1.00 116.27 ?  65  PHE A CE1 1 
ATOM   6862 C CE2 . PHE E 5 65  ? 128.231 132.428 118.188 1.00 116.27 ?  65  PHE A CE2 1 
ATOM   6863 C CZ  . PHE E 5 65  ? 128.290 131.055 118.303 1.00 116.27 ?  65  PHE A CZ  1 
ATOM   6864 N N   . LEU E 5 66  ? 134.335 134.488 116.129 1.00 121.98 ?  66  LEU A N   1 
ATOM   6865 C CA  . LEU E 5 66  ? 135.392 135.152 115.374 1.00 121.98 ?  66  LEU A CA  1 
ATOM   6866 C C   . LEU E 5 66  ? 136.673 134.327 115.381 1.00 121.98 ?  66  LEU A C   1 
ATOM   6867 O O   . LEU E 5 66  ? 137.359 134.218 114.358 1.00 121.98 ?  66  LEU A O   1 
ATOM   6868 C CB  . LEU E 5 66  ? 135.641 136.545 115.951 1.00 121.98 ?  66  LEU A CB  1 
ATOM   6869 C CG  . LEU E 5 66  ? 134.541 137.577 115.700 1.00 121.98 ?  66  LEU A CG  1 
ATOM   6870 C CD1 . LEU E 5 66  ? 134.578 138.674 116.752 1.00 121.98 ?  66  LEU A CD1 1 
ATOM   6871 C CD2 . LEU E 5 66  ? 134.674 138.163 114.309 1.00 121.98 ?  66  LEU A CD2 1 
ATOM   6872 N N   . PHE E 5 67  ? 137.008 133.733 116.529 1.00 126.59 ?  67  PHE A N   1 
ATOM   6873 C CA  . PHE E 5 67  ? 138.195 132.889 116.616 1.00 126.59 ?  67  PHE A CA  1 
ATOM   6874 C C   . PHE E 5 67  ? 138.063 131.656 115.731 1.00 126.59 ?  67  PHE A C   1 
ATOM   6875 O O   . PHE E 5 67  ? 139.037 131.227 115.105 1.00 126.59 ?  67  PHE A O   1 
ATOM   6876 C CB  . PHE E 5 67  ? 138.442 132.485 118.069 1.00 126.59 ?  67  PHE A CB  1 
ATOM   6877 C CG  . PHE E 5 67  ? 139.420 131.358 118.228 1.00 126.59 ?  67  PHE A CG  1 
ATOM   6878 C CD1 . PHE E 5 67  ? 140.759 131.535 117.920 1.00 126.59 ?  67  PHE A CD1 1 
ATOM   6879 C CD2 . PHE E 5 67  ? 139.001 130.120 118.686 1.00 126.59 ?  67  PHE A CD2 1 
ATOM   6880 C CE1 . PHE E 5 67  ? 141.660 130.499 118.066 1.00 126.59 ?  67  PHE A CE1 1 
ATOM   6881 C CE2 . PHE E 5 67  ? 139.898 129.080 118.834 1.00 126.59 ?  67  PHE A CE2 1 
ATOM   6882 C CZ  . PHE E 5 67  ? 141.229 129.270 118.523 1.00 126.59 ?  67  PHE A CZ  1 
ATOM   6883 N N   . ASN E 5 68  ? 136.869 131.062 115.678 1.00 121.25 ?  68  ASN A N   1 
ATOM   6884 C CA  . ASN E 5 68  ? 136.662 129.923 114.787 1.00 121.25 ?  68  ASN A CA  1 
ATOM   6885 C C   . ASN E 5 68  ? 136.784 130.318 113.320 1.00 121.25 ?  68  ASN A C   1 
ATOM   6886 O O   . ASN E 5 68  ? 137.350 129.561 112.521 1.00 121.25 ?  68  ASN A O   1 
ATOM   6887 C CB  . ASN E 5 68  ? 135.304 129.273 115.051 1.00 121.25 ?  68  ASN A CB  1 
ATOM   6888 C CG  . ASN E 5 68  ? 135.201 128.681 116.440 1.00 121.25 ?  68  ASN A CG  1 
ATOM   6889 O OD1 . ASN E 5 68  ? 134.412 129.136 117.265 1.00 121.25 ?  68  ASN A OD1 1 
ATOM   6890 N ND2 . ASN E 5 68  ? 136.001 127.657 116.706 1.00 121.25 ?  68  ASN A ND2 1 
ATOM   6891 N N   . LEU E 5 69  ? 136.262 131.487 112.944 1.00 123.19 ?  69  LEU A N   1 
ATOM   6892 C CA  . LEU E 5 69  ? 136.442 131.959 111.572 1.00 123.19 ?  69  LEU A CA  1 
ATOM   6893 C C   . LEU E 5 69  ? 137.918 132.188 111.262 1.00 123.19 ?  69  LEU A C   1 
ATOM   6894 O O   . LEU E 5 69  ? 138.389 131.888 110.154 1.00 123.19 ?  69  LEU A O   1 
ATOM   6895 C CB  . LEU E 5 69  ? 135.635 133.238 111.348 1.00 123.19 ?  69  LEU A CB  1 
ATOM   6896 C CG  . LEU E 5 69  ? 135.979 134.070 110.111 1.00 123.19 ?  69  LEU A CG  1 
ATOM   6897 C CD1 . LEU E 5 69  ? 135.533 133.360 108.845 1.00 123.19 ?  69  LEU A CD1 1 
ATOM   6898 C CD2 . LEU E 5 69  ? 135.349 135.449 110.203 1.00 123.19 ?  69  LEU A CD2 1 
ATOM   6899 N N   . ALA E 5 70  ? 138.661 132.728 112.231 1.00 129.56 ?  70  ALA A N   1 
ATOM   6900 C CA  . ALA E 5 70  ? 140.099 132.902 112.063 1.00 129.56 ?  70  ALA A CA  1 
ATOM   6901 C C   . ALA E 5 70  ? 140.800 131.559 111.901 1.00 129.56 ?  70  ALA A C   1 
ATOM   6902 O O   . ALA E 5 70  ? 141.716 131.424 111.088 1.00 129.56 ?  70  ALA A O   1 
ATOM   6903 C CB  . ALA E 5 70  ? 140.677 133.671 113.250 1.00 129.56 ?  70  ALA A CB  1 
ATOM   6904 N N   . VAL E 5 71  ? 140.382 130.554 112.668 1.00 129.89 ?  71  VAL A N   1 
ATOM   6905 C CA  . VAL E 5 71  ? 140.954 129.219 112.517 1.00 129.89 ?  71  VAL A CA  1 
ATOM   6906 C C   . VAL E 5 71  ? 140.681 128.682 111.117 1.00 129.89 ?  71  VAL A C   1 
ATOM   6907 O O   . VAL E 5 71  ? 141.570 128.119 110.466 1.00 129.89 ?  71  VAL A O   1 
ATOM   6908 C CB  . VAL E 5 71  ? 140.403 128.278 113.605 1.00 129.89 ?  71  VAL A CB  1 
ATOM   6909 C CG1 . VAL E 5 71  ? 140.615 126.823 113.216 1.00 129.89 ?  71  VAL A CG1 1 
ATOM   6910 C CG2 . VAL E 5 71  ? 141.056 128.579 114.945 1.00 129.89 ?  71  VAL A CG2 1 
ATOM   6911 N N   . ALA E 5 72  ? 139.454 128.866 110.628 1.00 130.62 ?  72  ALA A N   1 
ATOM   6912 C CA  . ALA E 5 72  ? 139.089 128.355 109.309 1.00 130.62 ?  72  ALA A CA  1 
ATOM   6913 C C   . ALA E 5 72  ? 139.925 129.001 108.209 1.00 130.62 ?  72  ALA A C   1 
ATOM   6914 O O   . ALA E 5 72  ? 140.533 128.306 107.381 1.00 130.62 ?  72  ALA A O   1 
ATOM   6915 C CB  . ALA E 5 72  ? 137.600 128.584 109.054 1.00 130.62 ?  72  ALA A CB  1 
ATOM   6916 N N   . ASP E 5 73  ? 139.956 130.317 108.195 1.00 136.62 ?  73  ASP A N   1 
ATOM   6917 C CA  . ASP E 5 73  ? 140.742 131.010 107.204 1.00 136.62 ?  73  ASP A CA  1 
ATOM   6918 C C   . ASP E 5 73  ? 142.176 130.589 107.305 1.00 136.62 ?  73  ASP A C   1 
ATOM   6919 O O   . ASP E 5 73  ? 142.808 130.239 106.313 1.00 136.62 ?  73  ASP A O   1 
ATOM   6920 C CB  . ASP E 5 73  ? 140.688 132.486 107.494 1.00 136.62 ?  73  ASP A CB  1 
ATOM   6921 C CG  . ASP E 5 73  ? 139.735 133.212 106.611 1.00 136.62 ?  73  ASP A CG  1 
ATOM   6922 O OD1 . ASP E 5 73  ? 138.890 132.563 105.963 1.00 136.62 ?  73  ASP A OD1 1 
ATOM   6923 O OD2 . ASP E 5 73  ? 139.841 134.448 106.569 1.00 136.62 -1 73  ASP A OD2 1 
ATOM   6924 N N   . PHE E 5 74  ? 142.708 130.636 108.515 1.00 140.66 ?  74  PHE A N   1 
ATOM   6925 C CA  . PHE E 5 74  ? 144.113 130.301 108.719 1.00 140.66 ?  74  PHE A CA  1 
ATOM   6926 C C   . PHE E 5 74  ? 144.440 128.930 108.143 1.00 140.66 ?  74  PHE A C   1 
ATOM   6927 O O   . PHE E 5 74  ? 145.492 128.743 107.522 1.00 140.66 ?  74  PHE A O   1 
ATOM   6928 C CB  . PHE E 5 74  ? 144.455 130.355 110.207 1.00 140.66 ?  74  PHE A CB  1 
ATOM   6929 C CG  . PHE E 5 74  ? 145.897 130.061 110.507 1.00 140.66 ?  74  PHE A CG  1 
ATOM   6930 C CD1 . PHE E 5 74  ? 146.876 131.011 110.265 1.00 140.66 ?  74  PHE A CD1 1 
ATOM   6931 C CD2 . PHE E 5 74  ? 146.274 128.837 111.033 1.00 140.66 ?  74  PHE A CD2 1 
ATOM   6932 C CE1 . PHE E 5 74  ? 148.203 130.743 110.540 1.00 140.66 ?  74  PHE A CE1 1 
ATOM   6933 C CE2 . PHE E 5 74  ? 147.599 128.564 111.310 1.00 140.66 ?  74  PHE A CE2 1 
ATOM   6934 C CZ  . PHE E 5 74  ? 148.565 129.518 111.063 1.00 140.66 ?  74  PHE A CZ  1 
ATOM   6935 N N   . LEU E 5 75  ? 143.551 127.956 108.340 1.00 137.98 ?  75  LEU A N   1 
ATOM   6936 C CA  . LEU E 5 75  ? 143.756 126.650 107.723 1.00 137.98 ?  75  LEU A CA  1 
ATOM   6937 C C   . LEU E 5 75  ? 143.769 126.766 106.204 1.00 137.98 ?  75  LEU A C   1 
ATOM   6938 O O   . LEU E 5 75  ? 144.618 126.165 105.532 1.00 137.98 ?  75  LEU A O   1 
ATOM   6939 C CB  . LEU E 5 75  ? 142.674 125.676 108.187 1.00 137.98 ?  75  LEU A CB  1 
ATOM   6940 C CG  . LEU E 5 75  ? 143.064 124.695 109.293 1.00 137.98 ?  75  LEU A CG  1 
ATOM   6941 C CD1 . LEU E 5 75  ? 143.454 125.438 110.560 1.00 137.98 ?  75  LEU A CD1 1 
ATOM   6942 C CD2 . LEU E 5 75  ? 141.925 123.729 109.572 1.00 137.98 ?  75  LEU A CD2 1 
ATOM   6943 N N   . LEU E 5 76  ? 142.848 127.555 105.648 1.00 140.86 ?  76  LEU A N   1 
ATOM   6944 C CA  . LEU E 5 76  ? 142.810 127.727 104.198 1.00 140.86 ?  76  LEU A CA  1 
ATOM   6945 C C   . LEU E 5 76  ? 144.107 128.350 103.683 1.00 140.86 ?  76  LEU A C   1 
ATOM   6946 O O   . LEU E 5 76  ? 144.686 127.849 102.719 1.00 140.86 ?  76  LEU A O   1 
ATOM   6947 C CB  . LEU E 5 76  ? 141.604 128.582 103.801 1.00 140.86 ?  76  LEU A CB  1 
ATOM   6948 C CG  . LEU E 5 76  ? 141.318 128.643 102.285 1.00 140.86 ?  76  LEU A CG  1 
ATOM   6949 C CD1 . LEU E 5 76  ? 139.824 128.864 102.036 1.00 140.86 ?  76  LEU A CD1 1 
ATOM   6950 C CD2 . LEU E 5 76  ? 142.066 129.776 101.573 1.00 140.86 ?  76  LEU A CD2 1 
ATOM   6951 N N   . ILE E 5 77  ? 144.592 129.395 104.357 1.00 144.72 ?  77  ILE A N   1 
ATOM   6952 C CA  . ILE E 5 77  ? 145.794 130.074 103.880 1.00 144.72 ?  77  ILE A CA  1 
ATOM   6953 C C   . ILE E 5 77  ? 147.036 129.204 104.055 1.00 144.72 ?  77  ILE A C   1 
ATOM   6954 O O   . ILE E 5 77  ? 147.962 129.277 103.239 1.00 144.72 ?  77  ILE A O   1 
ATOM   6955 C CB  . ILE E 5 77  ? 145.952 131.446 104.563 1.00 144.72 ?  77  ILE A CB  1 
ATOM   6956 C CG1 . ILE E 5 77  ? 146.112 131.276 106.071 1.00 144.72 ?  77  ILE A CG1 1 
ATOM   6957 C CG2 . ILE E 5 77  ? 144.782 132.357 104.218 1.00 144.72 ?  77  ILE A CG2 1 
ATOM   6958 C CD1 . ILE E 5 77  ? 146.495 132.516 106.817 1.00 144.72 ?  77  ILE A CD1 1 
ATOM   6959 N N   . ILE E 5 78  ? 147.102 128.381 105.108 1.00 144.52 ?  78  ILE A N   1 
ATOM   6960 C CA  . ILE E 5 78  ? 148.281 127.532 105.266 1.00 144.52 ?  78  ILE A CA  1 
ATOM   6961 C C   . ILE E 5 78  ? 148.232 126.360 104.292 1.00 144.52 ?  78  ILE A C   1 
ATOM   6962 O O   . ILE E 5 78  ? 149.269 125.777 103.954 1.00 144.52 ?  78  ILE A O   1 
ATOM   6963 C CB  . ILE E 5 78  ? 148.442 127.051 106.721 1.00 144.52 ?  78  ILE A CB  1 
ATOM   6964 C CG1 . ILE E 5 78  ? 147.255 126.193 107.155 1.00 144.52 ?  78  ILE A CG1 1 
ATOM   6965 C CG2 . ILE E 5 78  ? 148.637 128.236 107.657 1.00 144.52 ?  78  ILE A CG2 1 
ATOM   6966 C CD1 . ILE E 5 78  ? 147.458 125.502 108.484 1.00 144.52 ?  78  ILE A CD1 1 
ATOM   6967 N N   . CYS E 5 79  ? 147.034 125.980 103.838 1.00 148.27 ?  79  CYS A N   1 
ATOM   6968 C CA  . CYS E 5 79  ? 146.949 124.999 102.761 1.00 148.27 ?  79  CYS A CA  1 
ATOM   6969 C C   . CYS E 5 79  ? 147.167 125.619 101.375 1.00 148.27 ?  79  CYS A C   1 
ATOM   6970 O O   . CYS E 5 79  ? 147.490 124.901 100.425 1.00 148.27 ?  79  CYS A O   1 
ATOM   6971 C CB  . CYS E 5 79  ? 145.597 124.283 102.799 1.00 148.27 ?  79  CYS A CB  1 
ATOM   6972 S SG  . CYS E 5 79  ? 145.286 123.362 104.323 1.00 148.27 ?  79  CYS A SG  1 
ATOM   6973 N N   . LEU E 5 80  ? 147.050 126.946 101.255 1.00 153.24 ?  80  LEU A N   1 
ATOM   6974 C CA  . LEU E 5 80  ? 147.283 127.651 99.997  1.00 153.24 ?  80  LEU A CA  1 
ATOM   6975 C C   . LEU E 5 80  ? 148.637 127.349 99.341  1.00 153.24 ?  80  LEU A C   1 
ATOM   6976 O O   . LEU E 5 80  ? 148.637 127.137 98.127  1.00 153.24 ?  80  LEU A O   1 
ATOM   6977 C CB  . LEU E 5 80  ? 147.088 129.153 100.206 1.00 153.24 ?  80  LEU A CB  1 
ATOM   6978 C CG  . LEU E 5 80  ? 146.956 129.984 98.916  1.00 153.24 ?  80  LEU A CG  1 
ATOM   6979 C CD1 . LEU E 5 80  ? 146.017 131.166 99.147  1.00 153.24 ?  80  LEU A CD1 1 
ATOM   6980 C CD2 . LEU E 5 80  ? 148.318 130.541 98.488  1.00 153.24 ?  80  LEU A CD2 1 
ATOM   6981 N N   . PRO E 5 81  ? 149.781 127.272 100.054 1.00 156.67 ?  81  PRO A N   1 
ATOM   6982 C CA  . PRO E 5 81  ? 151.063 127.059 99.356  1.00 156.67 ?  81  PRO A CA  1 
ATOM   6983 C C   . PRO E 5 81  ? 151.151 125.753 98.546  1.00 156.67 ?  81  PRO A C   1 
ATOM   6984 O O   . PRO E 5 81  ? 151.880 125.735 97.556  1.00 156.67 ?  81  PRO A O   1 
ATOM   6985 C CB  . PRO E 5 81  ? 152.094 127.039 100.496 1.00 156.67 ?  81  PRO A CB  1 
ATOM   6986 C CG  . PRO E 5 81  ? 151.304 126.956 101.761 1.00 156.67 ?  81  PRO A CG  1 
ATOM   6987 C CD  . PRO E 5 81  ? 150.004 127.616 101.467 1.00 156.67 ?  81  PRO A CD  1 
ATOM   6988 N N   . PHE E 5 82  ? 150.356 124.717 98.849  1.00 159.01 ?  82  PHE A N   1 
ATOM   6989 C CA  . PHE E 5 82  ? 150.286 123.506 98.016  1.00 159.01 ?  82  PHE A CA  1 
ATOM   6990 C C   . PHE E 5 82  ? 149.609 123.760 96.663  1.00 159.01 ?  82  PHE A C   1 
ATOM   6991 O O   . PHE E 5 82  ? 150.065 123.253 95.636  1.00 159.01 ?  82  PHE A O   1 
ATOM   6992 C CB  . PHE E 5 82  ? 149.531 122.403 98.763  1.00 159.01 ?  82  PHE A CB  1 
ATOM   6993 C CG  . PHE E 5 82  ? 150.231 121.895 100.004 1.00 159.01 ?  82  PHE A CG  1 
ATOM   6994 C CD1 . PHE E 5 82  ? 151.265 120.967 99.911  1.00 159.01 ?  82  PHE A CD1 1 
ATOM   6995 C CD2 . PHE E 5 82  ? 149.858 122.320 101.276 1.00 159.01 ?  82  PHE A CD2 1 
ATOM   6996 C CE1 . PHE E 5 82  ? 151.889 120.471 101.039 1.00 159.01 ?  82  PHE A CE1 1 
ATOM   6997 C CE2 . PHE E 5 82  ? 150.478 121.828 102.408 1.00 159.01 ?  82  PHE A CE2 1 
ATOM   6998 C CZ  . PHE E 5 82  ? 151.495 120.902 102.289 1.00 159.01 ?  82  PHE A CZ  1 
ATOM   6999 N N   . VAL E 5 83  ? 148.561 124.591 96.640  1.00 162.78 ?  83  VAL A N   1 
ATOM   7000 C CA  . VAL E 5 83  ? 147.904 125.017 95.395  1.00 162.78 ?  83  VAL A CA  1 
ATOM   7001 C C   . VAL E 5 83  ? 148.762 126.025 94.632  1.00 162.78 ?  83  VAL A C   1 
ATOM   7002 O O   . VAL E 5 83  ? 148.771 126.028 93.407  1.00 162.78 ?  83  VAL A O   1 
ATOM   7003 C CB  . VAL E 5 83  ? 146.477 125.532 95.675  1.00 162.78 ?  83  VAL A CB  1 
ATOM   7004 C CG1 . VAL E 5 83  ? 146.285 127.056 95.651  1.00 162.78 ?  83  VAL A CG1 1 
ATOM   7005 C CG2 . VAL E 5 83  ? 145.511 124.921 94.669  1.00 162.78 ?  83  VAL A CG2 1 
ATOM   7006 N N   . MET E 5 84  ? 149.575 126.800 95.348  1.00 165.25 ?  84  MET A N   1 
ATOM   7007 C CA  . MET E 5 84  ? 150.611 127.636 94.761  1.00 165.25 ?  84  MET A CA  1 
ATOM   7008 C C   . MET E 5 84  ? 151.631 126.785 94.004  1.00 165.25 ?  84  MET A C   1 
ATOM   7009 O O   . MET E 5 84  ? 151.734 126.922 92.789  1.00 165.25 ?  84  MET A O   1 
ATOM   7010 C CB  . MET E 5 84  ? 151.259 128.461 95.873  1.00 165.25 ?  84  MET A CB  1 
ATOM   7011 C CG  . MET E 5 84  ? 152.202 129.534 95.353  1.00 165.25 ?  84  MET A CG  1 
ATOM   7012 S SD  . MET E 5 84  ? 151.411 130.814 94.368  1.00 165.25 ?  84  MET A SD  1 
ATOM   7013 C CE  . MET E 5 84  ? 152.803 131.392 93.401  1.00 165.25 ?  84  MET A CE  1 
ATOM   7014 N N   . ASP E 5 85  ? 152.286 125.829 94.671  1.00 167.73 ?  85  ASP A N   1 
ATOM   7015 C CA  . ASP E 5 85  ? 153.314 124.991 94.042  1.00 167.73 ?  85  ASP A CA  1 
ATOM   7016 C C   . ASP E 5 85  ? 152.738 124.181 92.853  1.00 167.73 ?  85  ASP A C   1 
ATOM   7017 O O   . ASP E 5 85  ? 153.358 124.022 91.799  1.00 167.73 ?  85  ASP A O   1 
ATOM   7018 C CB  . ASP E 5 85  ? 153.935 124.043 95.089  1.00 167.73 ?  85  ASP A CB  1 
ATOM   7019 C CG  . ASP E 5 85  ? 155.277 123.498 94.645  1.00 167.73 ?  85  ASP A CG  1 
ATOM   7020 O OD1 . ASP E 5 85  ? 155.784 123.943 93.594  1.00 167.73 ?  85  ASP A OD1 1 
ATOM   7021 O OD2 . ASP E 5 85  ? 155.827 122.625 95.349  1.00 167.73 -1 85  ASP A OD2 1 
ATOM   7022 N N   . TYR E 5 86  ? 151.487 123.713 92.970  1.00 167.78 ?  86  TYR A N   1 
ATOM   7023 C CA  . TYR E 5 86  ? 150.725 123.144 91.851  1.00 167.78 ?  86  TYR A CA  1 
ATOM   7024 C C   . TYR E 5 86  ? 150.727 124.057 90.622  1.00 167.78 ?  86  TYR A C   1 
ATOM   7025 O O   . TYR E 5 86  ? 151.215 123.660 89.559  1.00 167.78 ?  86  TYR A O   1 
ATOM   7026 C CB  . TYR E 5 86  ? 149.278 122.887 92.279  1.00 167.78 ?  86  TYR A CB  1 
ATOM   7027 C CG  . TYR E 5 86  ? 148.350 122.536 91.129  1.00 167.78 ?  86  TYR A CG  1 
ATOM   7028 C CD1 . TYR E 5 86  ? 148.635 121.423 90.323  1.00 167.78 ?  86  TYR A CD1 1 
ATOM   7029 C CD2 . TYR E 5 86  ? 147.258 123.366 90.804  1.00 167.78 ?  86  TYR A CD2 1 
ATOM   7030 C CE1 . TYR E 5 86  ? 147.778 121.075 89.264  1.00 167.78 ?  86  TYR A CE1 1 
ATOM   7031 C CE2 . TYR E 5 86  ? 146.423 123.038 89.715  1.00 167.78 ?  86  TYR A CE2 1 
ATOM   7032 C CZ  . TYR E 5 86  ? 146.654 121.866 88.969  1.00 167.78 ?  86  TYR A CZ  1 
ATOM   7033 O OH  . TYR E 5 86  ? 145.822 121.519 87.950  1.00 167.78 ?  86  TYR A OH  1 
ATOM   7034 N N   . TYR E 5 87  ? 150.227 125.285 90.782  1.00 167.80 ?  87  TYR A N   1 
ATOM   7035 C CA  . TYR E 5 87  ? 150.142 126.240 89.690  1.00 167.80 ?  87  TYR A CA  1 
ATOM   7036 C C   . TYR E 5 87  ? 151.520 126.690 89.194  1.00 167.80 ?  87  TYR A C   1 
ATOM   7037 O O   . TYR E 5 87  ? 151.602 127.011 88.010  1.00 167.80 ?  87  TYR A O   1 
ATOM   7038 C CB  . TYR E 5 87  ? 149.281 127.451 90.090  1.00 167.80 ?  87  TYR A CB  1 
ATOM   7039 C CG  . TYR E 5 87  ? 147.810 127.173 90.366  1.00 167.80 ?  87  TYR A CG  1 
ATOM   7040 C CD1 . TYR E 5 87  ? 147.009 126.506 89.415  1.00 167.80 ?  87  TYR A CD1 1 
ATOM   7041 C CD2 . TYR E 5 87  ? 147.219 127.652 91.552  1.00 167.80 ?  87  TYR A CD2 1 
ATOM   7042 C CE1 . TYR E 5 87  ? 145.637 126.295 89.664  1.00 167.80 ?  87  TYR A CE1 1 
ATOM   7043 C CE2 . TYR E 5 87  ? 145.856 127.417 91.817  1.00 167.80 ?  87  TYR A CE2 1 
ATOM   7044 C CZ  . TYR E 5 87  ? 145.064 126.731 90.878  1.00 167.80 ?  87  TYR A CZ  1 
ATOM   7045 O OH  . TYR E 5 87  ? 143.750 126.520 91.146  1.00 167.80 ?  87  TYR A OH  1 
ATOM   7046 N N   . VAL E 5 88  ? 152.561 126.727 90.015  1.00 169.95 ?  88  VAL A N   1 
ATOM   7047 C CA  . VAL E 5 88  ? 153.834 127.275 89.548  1.00 169.95 ?  88  VAL A CA  1 
ATOM   7048 C C   . VAL E 5 88  ? 154.356 126.486 88.351  1.00 169.95 ?  88  VAL A C   1 
ATOM   7049 O O   . VAL E 5 88  ? 154.736 127.061 87.324  1.00 169.95 ?  88  VAL A O   1 
ATOM   7050 C CB  . VAL E 5 88  ? 154.864 127.306 90.692  1.00 169.95 ?  88  VAL A CB  1 
ATOM   7051 C CG1 . VAL E 5 88  ? 156.265 127.504 90.137  1.00 169.95 ?  88  VAL A CG1 1 
ATOM   7052 C CG2 . VAL E 5 88  ? 154.535 128.422 91.668  1.00 169.95 ?  88  VAL A CG2 1 
ATOM   7053 N N   . ARG E 5 89  ? 154.373 125.159 88.458  1.00 171.59 ?  89  ARG A N   1 
ATOM   7054 C CA  . ARG E 5 89  ? 155.035 124.319 87.459  1.00 171.59 ?  89  ARG A CA  1 
ATOM   7055 C C   . ARG E 5 89  ? 154.022 123.794 86.442  1.00 171.59 ?  89  ARG A C   1 
ATOM   7056 O O   . ARG E 5 89  ? 153.784 122.593 86.318  1.00 171.59 ?  89  ARG A O   1 
ATOM   7057 C CB  . ARG E 5 89  ? 155.783 123.176 88.140  1.00 171.59 ?  89  ARG A CB  1 
ATOM   7058 C CG  . ARG E 5 89  ? 156.542 123.576 89.392  1.00 171.59 ?  89  ARG A CG  1 
ATOM   7059 C CD  . ARG E 5 89  ? 156.594 122.426 90.384  1.00 171.59 ?  89  ARG A CD  1 
ATOM   7060 N NE  . ARG E 5 89  ? 155.274 122.098 90.910  1.00 171.59 ?  89  ARG A NE  1 
ATOM   7061 C CZ  . ARG E 5 89  ? 155.062 121.378 92.003  1.00 171.59 ?  89  ARG A CZ  1 
ATOM   7062 N NH1 . ARG E 5 89  ? 156.065 120.886 92.712  1.00 171.59 1  89  ARG A NH1 1 
ATOM   7063 N NH2 . ARG E 5 89  ? 153.856 121.209 92.453  1.00 171.59 1  89  ARG A NH2 1 
ATOM   7064 N N   . ARG E 5 90  ? 153.427 124.733 85.702  1.00 173.82 ?  90  ARG A N   1 
ATOM   7065 C CA  . ARG E 5 90  ? 152.598 124.412 84.535  1.00 173.82 ?  90  ARG A CA  1 
ATOM   7066 C C   . ARG E 5 90  ? 151.458 123.457 84.893  1.00 173.82 ?  90  ARG A C   1 
ATOM   7067 O O   . ARG E 5 90  ? 151.001 122.669 84.060  1.00 173.82 ?  90  ARG A O   1 
ATOM   7068 C CB  . ARG E 5 90  ? 153.461 123.836 83.405  1.00 173.82 ?  90  ARG A CB  1 
ATOM   7069 N N   . SER E 5 91  ? 150.988 123.527 86.137  1.00 173.68 ?  91  SER A N   1 
ATOM   7070 C CA  . SER E 5 91  ? 149.904 122.653 86.675  1.00 173.68 ?  91  SER A CA  1 
ATOM   7071 C C   . SER E 5 91  ? 150.202 121.136 86.736  1.00 173.68 ?  91  SER A C   1 
ATOM   7072 O O   . SER E 5 91  ? 149.331 120.294 86.544  1.00 173.68 ?  91  SER A O   1 
ATOM   7073 C CB  . SER E 5 91  ? 148.551 122.957 86.018  1.00 173.68 ?  91  SER A CB  1 
ATOM   7074 O OG  . SER E 5 91  ? 148.485 122.437 84.710  1.00 173.68 ?  91  SER A OG  1 
ATOM   7075 N N   . ASP E 5 92  ? 151.442 120.788 87.052  1.00 173.75 ?  92  ASP A N   1 
ATOM   7076 C CA  . ASP E 5 92  ? 152.030 119.457 86.921  1.00 173.75 ?  92  ASP A CA  1 
ATOM   7077 C C   . ASP E 5 92  ? 152.282 118.999 88.351  1.00 173.75 ?  92  ASP A C   1 
ATOM   7078 O O   . ASP E 5 92  ? 153.425 118.889 88.801  1.00 173.75 ?  92  ASP A O   1 
ATOM   7079 C CB  . ASP E 5 92  ? 153.329 119.502 86.121  1.00 173.75 ?  92  ASP A CB  1 
ATOM   7080 N N   . TRP E 5 93  ? 151.191 118.840 89.123  1.00 169.37 ?  93  TRP A N   1 
ATOM   7081 C CA  . TRP E 5 93  ? 151.157 118.287 90.489  1.00 169.37 ?  93  TRP A CA  1 
ATOM   7082 C C   . TRP E 5 93  ? 151.945 116.974 90.570  1.00 169.37 ?  93  TRP A C   1 
ATOM   7083 O O   . TRP E 5 93  ? 151.573 116.034 89.876  1.00 169.37 ?  93  TRP A O   1 
ATOM   7084 C CB  . TRP E 5 93  ? 149.692 117.930 90.804  1.00 169.37 ?  93  TRP A CB  1 
ATOM   7085 C CG  . TRP E 5 93  ? 149.480 117.377 92.174  1.00 169.37 ?  93  TRP A CG  1 
ATOM   7086 C CD1 . TRP E 5 93  ? 149.590 116.078 92.526  1.00 169.37 ?  93  TRP A CD1 1 
ATOM   7087 C CD2 . TRP E 5 93  ? 149.158 118.096 93.398  1.00 169.37 ?  93  TRP A CD2 1 
ATOM   7088 N NE1 . TRP E 5 93  ? 149.387 115.951 93.884  1.00 169.37 ?  93  TRP A NE1 1 
ATOM   7089 C CE2 . TRP E 5 93  ? 149.183 117.179 94.485  1.00 169.37 ?  93  TRP A CE2 1 
ATOM   7090 C CE3 . TRP E 5 93  ? 148.852 119.437 93.691  1.00 169.37 ?  93  TRP A CE3 1 
ATOM   7091 C CZ2 . TRP E 5 93  ? 148.995 117.602 95.810  1.00 169.37 ?  93  TRP A CZ2 1 
ATOM   7092 C CZ3 . TRP E 5 93  ? 148.654 119.872 95.015  1.00 169.37 ?  93  TRP A CZ3 1 
ATOM   7093 C CH2 . TRP E 5 93  ? 148.741 118.956 96.077  1.00 169.37 ?  93  TRP A CH2 1 
ATOM   7094 N N   . LYS E 5 94  ? 152.973 116.878 91.434  1.00 170.20 ?  94  LYS A N   1 
ATOM   7095 C CA  . LYS E 5 94  ? 153.816 115.692 91.524  1.00 170.20 ?  94  LYS A CA  1 
ATOM   7096 C C   . LYS E 5 94  ? 153.449 114.744 92.655  1.00 170.20 ?  94  LYS A C   1 
ATOM   7097 O O   . LYS E 5 94  ? 153.782 113.556 92.580  1.00 170.20 ?  94  LYS A O   1 
ATOM   7098 C CB  . LYS E 5 94  ? 155.282 116.110 91.693  1.00 170.20 ?  94  LYS A CB  1 
ATOM   7099 N N   . PHE E 5 95  ? 152.778 115.228 93.698  1.00 169.09 ?  95  PHE A N   1 
ATOM   7100 C CA  . PHE E 5 95  ? 152.475 114.389 94.848  1.00 169.09 ?  95  PHE A CA  1 
ATOM   7101 C C   . PHE E 5 95  ? 151.421 113.344 94.477  1.00 169.09 ?  95  PHE A C   1 
ATOM   7102 O O   . PHE E 5 95  ? 150.921 113.289 93.350  1.00 169.09 ?  95  PHE A O   1 
ATOM   7103 C CB  . PHE E 5 95  ? 152.011 115.246 96.025  1.00 169.09 ?  95  PHE A CB  1 
ATOM   7104 N N   . GLY E 5 96  ? 151.077 112.503 95.450  1.00 165.55 ?  96  GLY A N   1 
ATOM   7105 C CA  . GLY E 5 96  ? 150.206 111.376 95.206  1.00 165.55 ?  96  GLY A CA  1 
ATOM   7106 C C   . GLY E 5 96  ? 148.729 111.716 95.287  1.00 165.55 ?  96  GLY A C   1 
ATOM   7107 O O   . GLY E 5 96  ? 148.316 112.874 95.355  1.00 165.55 ?  96  GLY A O   1 
ATOM   7108 N N   . ASP E 5 97  ? 147.919 110.655 95.271  1.00 164.24 ?  97  ASP A N   1 
ATOM   7109 C CA  . ASP E 5 97  ? 146.469 110.800 95.369  1.00 164.24 ?  97  ASP A CA  1 
ATOM   7110 C C   . ASP E 5 97  ? 146.059 111.417 96.702  1.00 164.24 ?  97  ASP A C   1 
ATOM   7111 O O   . ASP E 5 97  ? 145.315 112.408 96.734  1.00 164.24 ?  97  ASP A O   1 
ATOM   7112 C CB  . ASP E 5 97  ? 145.814 109.429 95.182  1.00 164.24 ?  97  ASP A CB  1 
ATOM   7113 C CG  . ASP E 5 97  ? 144.320 109.511 94.941  1.00 164.24 ?  97  ASP A CG  1 
ATOM   7114 O OD1 . ASP E 5 97  ? 143.745 110.609 95.065  1.00 164.24 ?  97  ASP A OD1 1 
ATOM   7115 O OD2 . ASP E 5 97  ? 143.715 108.465 94.625  1.00 164.24 -1 97  ASP A OD2 1 
ATOM   7116 N N   . ILE E 5 98  ? 146.538 110.842 97.808  1.00 161.74 ?  98  ILE A N   1 
ATOM   7117 C CA  . ILE E 5 98  ? 146.148 111.329 99.133  1.00 161.74 ?  98  ILE A CA  1 
ATOM   7118 C C   . ILE E 5 98  ? 146.525 112.791 99.347  1.00 161.74 ?  98  ILE A C   1 
ATOM   7119 O O   . ILE E 5 98  ? 145.698 113.542 99.891  1.00 161.74 ?  98  ILE A O   1 
ATOM   7120 C CB  . ILE E 5 98  ? 146.720 110.407 100.223 1.00 161.74 ?  98  ILE A CB  1 
ATOM   7121 C CG1 . ILE E 5 98  ? 146.494 108.938 99.856  1.00 161.74 ?  98  ILE A CG1 1 
ATOM   7122 C CG2 . ILE E 5 98  ? 146.095 110.727 101.573 1.00 161.74 ?  98  ILE A CG2 1 
ATOM   7123 C CD1 . ILE E 5 98  ? 145.062 108.479 100.015 1.00 161.74 ?  98  ILE A CD1 1 
ATOM   7124 N N   . PRO E 5 99  ? 147.731 113.257 98.988  1.00 163.25 ?  99  PRO A N   1 
ATOM   7125 C CA  . PRO E 5 99  ? 148.035 114.684 99.201  1.00 163.25 ?  99  PRO A CA  1 
ATOM   7126 C C   . PRO E 5 99  ? 147.100 115.613 98.425  1.00 163.25 ?  99  PRO A C   1 
ATOM   7127 O O   . PRO E 5 99  ? 146.612 116.590 98.989  1.00 163.25 ?  99  PRO A O   1 
ATOM   7128 C CB  . PRO E 5 99  ? 149.457 114.822 98.641  1.00 163.25 ?  99  PRO A CB  1 
ATOM   7129 C CG  . PRO E 5 99  ? 150.049 113.483 98.815  1.00 163.25 ?  99  PRO A CG  1 
ATOM   7130 C CD  . PRO E 5 99  ? 148.934 112.513 98.565  1.00 163.25 ?  99  PRO A CD  1 
ATOM   7131 N N   . CYS E 5 100 ? 146.814 115.310 97.153  1.00 162.15 ?  100 CYS A N   1 
ATOM   7132 C CA  . CYS E 5 100 ? 145.989 116.195 96.333  1.00 162.15 ?  100 CYS A CA  1 
ATOM   7133 C C   . CYS E 5 100 ? 144.545 116.184 96.829  1.00 162.15 ?  100 CYS A C   1 
ATOM   7134 O O   . CYS E 5 100 ? 143.961 117.244 97.062  1.00 162.15 ?  100 CYS A O   1 
ATOM   7135 C CB  . CYS E 5 100 ? 146.149 115.824 94.855  1.00 162.15 ?  100 CYS A CB  1 
ATOM   7136 S SG  . CYS E 5 100 ? 144.974 114.666 94.121  1.00 162.15 ?  100 CYS A SG  1 
ATOM   7137 N N   . ARG E 5 101 ? 144.038 115.005 97.206  1.00 159.42 ?  101 ARG A N   1 
ATOM   7138 C CA  . ARG E 5 101 ? 142.735 114.875 97.843  1.00 159.42 ?  101 ARG A CA  1 
ATOM   7139 C C   . ARG E 5 101 ? 142.622 115.683 99.114  1.00 159.42 ?  101 ARG A C   1 
ATOM   7140 O O   . ARG E 5 101 ? 141.672 116.451 99.269  1.00 159.42 ?  101 ARG A O   1 
ATOM   7141 C CB  . ARG E 5 101 ? 142.462 113.414 98.193  1.00 159.42 ?  101 ARG A CB  1 
ATOM   7142 C CG  . ARG E 5 101 ? 141.998 112.580 97.015  1.00 159.42 ?  101 ARG A CG  1 
ATOM   7143 C CD  . ARG E 5 101 ? 140.487 112.617 96.891  1.00 159.42 ?  101 ARG A CD  1 
ATOM   7144 N NE  . ARG E 5 101 ? 140.022 113.892 96.354  1.00 159.42 ?  101 ARG A NE  1 
ATOM   7145 C CZ  . ARG E 5 101 ? 139.590 114.879 97.105  1.00 159.42 ?  101 ARG A CZ  1 
ATOM   7146 N NH1 . ARG E 5 101 ? 139.584 114.811 98.418  1.00 159.42 1  101 ARG A NH1 1 
ATOM   7147 N NH2 . ARG E 5 101 ? 139.202 115.980 96.536  1.00 159.42 1  101 ARG A NH2 1 
ATOM   7148 N N   . LEU E 5 102 ? 143.544 115.469 100.043 1.00 154.85 ?  102 LEU A N   1 
ATOM   7149 C CA  . LEU E 5 102 ? 143.500 116.184 101.312 1.00 154.85 ?  102 LEU A CA  1 
ATOM   7150 C C   . LEU E 5 102 ? 143.575 117.712 101.126 1.00 154.85 ?  102 LEU A C   1 
ATOM   7151 O O   . LEU E 5 102 ? 142.845 118.437 101.794 1.00 154.85 ?  102 LEU A O   1 
ATOM   7152 C CB  . LEU E 5 102 ? 144.658 115.741 102.206 1.00 154.85 ?  102 LEU A CB  1 
ATOM   7153 C CG  . LEU E 5 102 ? 144.577 116.174 103.671 1.00 154.85 ?  102 LEU A CG  1 
ATOM   7154 C CD1 . LEU E 5 102 ? 143.641 115.260 104.447 1.00 154.85 ?  102 LEU A CD1 1 
ATOM   7155 C CD2 . LEU E 5 102 ? 145.959 116.194 104.302 1.00 154.85 ?  102 LEU A CD2 1 
ATOM   7156 N N   . VAL E 5 103 ? 144.375 118.215 100.180 1.00 152.77 ?  103 VAL A N   1 
ATOM   7157 C CA  . VAL E 5 103 ? 144.428 119.657 99.879  1.00 152.77 ?  103 VAL A CA  1 
ATOM   7158 C C   . VAL E 5 103 ? 143.079 120.147 99.340  1.00 152.77 ?  103 VAL A C   1 
ATOM   7159 O O   . VAL E 5 103 ? 142.512 121.081 99.905  1.00 152.77 ?  103 VAL A O   1 
ATOM   7160 C CB  . VAL E 5 103 ? 145.617 119.979 98.949  1.00 152.77 ?  103 VAL A CB  1 
ATOM   7161 C CG1 . VAL E 5 103 ? 145.581 121.402 98.375  1.00 152.77 ?  103 VAL A CG1 1 
ATOM   7162 C CG2 . VAL E 5 103 ? 146.926 119.848 99.742  1.00 152.77 ?  103 VAL A CG2 1 
ATOM   7163 N N   . LEU E 5 104 ? 142.473 119.441 98.379  1.00 149.50 ?  104 LEU A N   1 
ATOM   7164 C CA  . LEU E 5 104 ? 141.134 119.758 97.855  1.00 149.50 ?  104 LEU A CA  1 
ATOM   7165 C C   . LEU E 5 104 ? 140.025 119.690 98.925  1.00 149.50 ?  104 LEU A C   1 
ATOM   7166 O O   . LEU E 5 104 ? 139.088 120.486 98.881  1.00 149.50 ?  104 LEU A O   1 
ATOM   7167 C CB  . LEU E 5 104 ? 140.801 118.792 96.701  1.00 149.50 ?  104 LEU A CB  1 
ATOM   7168 C CG  . LEU E 5 104 ? 141.179 119.275 95.292  1.00 149.50 ?  104 LEU A CG  1 
ATOM   7169 C CD1 . LEU E 5 104 ? 142.653 119.616 95.117  1.00 149.50 ?  104 LEU A CD1 1 
ATOM   7170 C CD2 . LEU E 5 104 ? 140.826 118.180 94.281  1.00 149.50 ?  104 LEU A CD2 1 
ATOM   7171 N N   . PHE E 5 105 ? 140.091 118.737 99.862  1.00 145.66 ?  105 PHE A N   1 
ATOM   7172 C CA  . PHE E 5 105 ? 139.161 118.669 100.997 1.00 145.66 ?  105 PHE A CA  1 
ATOM   7173 C C   . PHE E 5 105 ? 139.354 119.860 101.934 1.00 145.66 ?  105 PHE A C   1 
ATOM   7174 O O   . PHE E 5 105 ? 138.371 120.509 102.280 1.00 145.66 ?  105 PHE A O   1 
ATOM   7175 C CB  . PHE E 5 105 ? 139.321 117.342 101.757 1.00 145.66 ?  105 PHE A CB  1 
ATOM   7176 C CG  . PHE E 5 105 ? 138.963 117.407 103.215 1.00 145.66 ?  105 PHE A CG  1 
ATOM   7177 C CD1 . PHE E 5 105 ? 137.638 117.408 103.615 1.00 145.66 ?  105 PHE A CD1 1 
ATOM   7178 C CD2 . PHE E 5 105 ? 139.950 117.465 104.185 1.00 145.66 ?  105 PHE A CD2 1 
ATOM   7179 C CE1 . PHE E 5 105 ? 137.303 117.469 104.953 1.00 145.66 ?  105 PHE A CE1 1 
ATOM   7180 C CE2 . PHE E 5 105 ? 139.621 117.527 105.525 1.00 145.66 ?  105 PHE A CE2 1 
ATOM   7181 C CZ  . PHE E 5 105 ? 138.296 117.528 105.909 1.00 145.66 ?  105 PHE A CZ  1 
ATOM   7182 N N   . MET E 5 106 ? 140.600 120.186 102.288 1.00 145.26 ?  106 MET A N   1 
ATOM   7183 C CA  . MET E 5 106 ? 140.881 121.300 103.184 1.00 145.26 ?  106 MET A CA  1 
ATOM   7184 C C   . MET E 5 106 ? 140.398 122.622 102.568 1.00 145.26 ?  106 MET A C   1 
ATOM   7185 O O   . MET E 5 106 ? 139.741 123.403 103.246 1.00 145.26 ?  106 MET A O   1 
ATOM   7186 C CB  . MET E 5 106 ? 142.378 121.386 103.507 1.00 145.26 ?  106 MET A CB  1 
ATOM   7187 C CG  . MET E 5 106 ? 142.920 120.218 104.309 1.00 145.26 ?  106 MET A CG  1 
ATOM   7188 S SD  . MET E 5 106 ? 142.123 120.059 105.918 1.00 145.26 ?  106 MET A SD  1 
ATOM   7189 C CE  . MET E 5 106 ? 142.759 121.509 106.751 1.00 145.26 ?  106 MET A CE  1 
ATOM   7190 N N   . PHE E 5 107 ? 140.628 122.861 101.274 1.00 145.50 ?  107 PHE A N   1 
ATOM   7191 C CA  . PHE E 5 107 ? 140.125 124.049 100.574 1.00 145.50 ?  107 PHE A CA  1 
ATOM   7192 C C   . PHE E 5 107 ? 138.595 124.165 100.615 1.00 145.50 ?  107 PHE A C   1 
ATOM   7193 O O   . PHE E 5 107 ? 138.065 125.184 101.067 1.00 145.50 ?  107 PHE A O   1 
ATOM   7194 C CB  . PHE E 5 107 ? 140.625 124.037 99.125  1.00 145.50 ?  107 PHE A CB  1 
ATOM   7195 C CG  . PHE E 5 107 ? 141.872 124.863 98.915  1.00 145.50 ?  107 PHE A CG  1 
ATOM   7196 C CD1 . PHE E 5 107 ? 141.746 126.246 98.696  1.00 145.50 ?  107 PHE A CD1 1 
ATOM   7197 C CD2 . PHE E 5 107 ? 143.146 124.268 98.928  1.00 145.50 ?  107 PHE A CD2 1 
ATOM   7198 C CE1 . PHE E 5 107 ? 142.885 127.023 98.443  1.00 145.50 ?  107 PHE A CE1 1 
ATOM   7199 C CE2 . PHE E 5 107 ? 144.289 125.045 98.686  1.00 145.50 ?  107 PHE A CE2 1 
ATOM   7200 C CZ  . PHE E 5 107 ? 144.147 126.415 98.411  1.00 145.50 ?  107 PHE A CZ  1 
ATOM   7201 N N   . ALA E 5 108 ? 137.885 123.098 100.236 1.00 136.70 ?  108 ALA A N   1 
ATOM   7202 C CA  . ALA E 5 108 ? 136.426 123.078 100.257 1.00 136.70 ?  108 ALA A CA  1 
ATOM   7203 C C   . ALA E 5 108 ? 135.868 123.242 101.681 1.00 136.70 ?  108 ALA A C   1 
ATOM   7204 O O   . ALA E 5 108 ? 134.999 124.085 101.906 1.00 136.70 ?  108 ALA A O   1 
ATOM   7205 C CB  . ALA E 5 108 ? 135.953 121.774 99.606  1.00 136.70 ?  108 ALA A CB  1 
ATOM   7206 N N   . MET E 5 109 ? 136.412 122.505 102.655 1.00 135.28 ?  109 MET A N   1 
ATOM   7207 C CA  . MET E 5 109 ? 135.938 122.529 104.040 1.00 135.28 ?  109 MET A CA  1 
ATOM   7208 C C   . MET E 5 109 ? 136.198 123.870 104.709 1.00 135.28 ?  109 MET A C   1 
ATOM   7209 O O   . MET E 5 109 ? 135.334 124.380 105.427 1.00 135.28 ?  109 MET A O   1 
ATOM   7210 C CB  . MET E 5 109 ? 136.575 121.382 104.836 1.00 135.28 ?  109 MET A CB  1 
ATOM   7211 C CG  . MET E 5 109 ? 136.084 121.223 106.270 1.00 135.28 ?  109 MET A CG  1 
ATOM   7212 S SD  . MET E 5 109 ? 136.870 122.320 107.463 1.00 135.28 ?  109 MET A SD  1 
ATOM   7213 C CE  . MET E 5 109 ? 138.501 121.588 107.574 1.00 135.28 ?  109 MET A CE  1 
ATOM   7214 N N   . ASN E 5 110 ? 137.364 124.472 104.480 1.00 133.90 ?  110 ASN A N   1 
ATOM   7215 C CA  . ASN E 5 110 ? 137.663 125.752 105.098 1.00 133.90 ?  110 ASN A CA  1 
ATOM   7216 C C   . ASN E 5 110 ? 136.851 126.874 104.472 1.00 133.90 ?  110 ASN A C   1 
ATOM   7217 O O   . ASN E 5 110 ? 136.418 127.784 105.184 1.00 133.90 ?  110 ASN A O   1 
ATOM   7218 C CB  . ASN E 5 110 ? 139.158 126.053 105.013 1.00 133.90 ?  110 ASN A CB  1 
ATOM   7219 C CG  . ASN E 5 110 ? 139.977 125.177 105.939 1.00 133.90 ?  110 ASN A CG  1 
ATOM   7220 O OD1 . ASN E 5 110 ? 139.611 125.168 107.216 1.00 133.90 ?  110 ASN A OD1 1 
ATOM   7221 N ND2 . ASN E 5 110 ? 140.913 124.502 105.513 1.00 133.90 ?  110 ASN A ND2 1 
ATOM   7222 N N   . ARG E 5 111 ? 136.617 126.860 103.144 1.00 128.00 ?  111 ARG A N   1 
ATOM   7223 C CA  . ARG E 5 111 ? 135.712 127.836 102.504 1.00 128.00 ?  111 ARG A CA  1 
ATOM   7224 C C   . ARG E 5 111 ? 134.323 127.712 103.110 1.00 128.00 ?  111 ARG A C   1 
ATOM   7225 O O   . ARG E 5 111 ? 133.697 128.721 103.466 1.00 128.00 ?  111 ARG A O   1 
ATOM   7226 C CB  . ARG E 5 111 ? 135.654 127.652 100.974 1.00 128.00 ?  111 ARG A CB  1 
ATOM   7227 C CG  . ARG E 5 111 ? 134.444 128.396 100.354 1.00 128.00 ?  111 ARG A CG  1 
ATOM   7228 C CD  . ARG E 5 111 ? 134.462 128.505 98.828  1.00 128.00 ?  111 ARG A CD  1 
ATOM   7229 N NE  . ARG E 5 111 ? 134.644 127.210 98.173  1.00 128.00 ?  111 ARG A NE  1 
ATOM   7230 C CZ  . ARG E 5 111 ? 135.768 126.723 97.681  1.00 128.00 ?  111 ARG A CZ  1 
ATOM   7231 N NH1 . ARG E 5 111 ? 136.883 127.400 97.640  1.00 128.00 1  111 ARG A NH1 1 
ATOM   7232 N NH2 . ARG E 5 111 ? 135.780 125.512 97.229  1.00 128.00 1  111 ARG A NH2 1 
ATOM   7233 N N   . GLN E 5 112 ? 133.811 126.481 103.218 1.00 123.60 ?  112 GLN A N   1 
ATOM   7234 C CA  . GLN E 5 112 ? 132.475 126.283 103.767 1.00 123.60 ?  112 GLN A CA  1 
ATOM   7235 C C   . GLN E 5 112 ? 132.401 126.737 105.219 1.00 123.60 ?  112 GLN A C   1 
ATOM   7236 O O   . GLN E 5 112 ? 131.418 127.361 105.632 1.00 123.60 ?  112 GLN A O   1 
ATOM   7237 C CB  . GLN E 5 112 ? 132.068 124.816 103.640 1.00 123.60 ?  112 GLN A CB  1 
ATOM   7238 C CG  . GLN E 5 112 ? 130.623 124.538 104.013 1.00 123.60 ?  112 GLN A CG  1 
ATOM   7239 C CD  . GLN E 5 112 ? 129.687 124.643 102.827 1.00 123.60 ?  112 GLN A CD  1 
ATOM   7240 O OE1 . GLN E 5 112 ? 129.963 124.106 101.755 1.00 123.60 ?  112 GLN A OE1 1 
ATOM   7241 N NE2 . GLN E 5 112 ? 128.571 125.338 103.013 1.00 123.60 ?  112 GLN A NE2 1 
ATOM   7242 N N   . GLY E 5 113 ? 133.432 126.434 106.009 1.00 117.99 ?  113 GLY A N   1 
ATOM   7243 C CA  . GLY E 5 113 ? 133.438 126.859 107.398 1.00 117.99 ?  113 GLY A CA  1 
ATOM   7244 C C   . GLY E 5 113 ? 133.519 128.364 107.549 1.00 117.99 ?  113 GLY A C   1 
ATOM   7245 O O   . GLY E 5 113 ? 132.866 128.944 108.420 1.00 117.99 ?  113 GLY A O   1 
ATOM   7246 N N   . SER E 5 114 ? 134.319 129.020 106.705 1.00 115.78 ?  114 SER A N   1 
ATOM   7247 C CA  . SER E 5 114 ? 134.389 130.475 106.739 1.00 115.78 ?  114 SER A CA  1 
ATOM   7248 C C   . SER E 5 114 ? 133.040 131.092 106.398 1.00 115.78 ?  114 SER A C   1 
ATOM   7249 O O   . SER E 5 114 ? 132.598 132.035 107.062 1.00 115.78 ?  114 SER A O   1 
ATOM   7250 C CB  . SER E 5 114 ? 135.468 130.972 105.779 1.00 115.78 ?  114 SER A CB  1 
ATOM   7251 O OG  . SER E 5 114 ? 135.140 130.660 104.437 1.00 115.78 ?  114 SER A OG  1 
ATOM   7252 N N   . ILE E 5 115 ? 132.361 130.559 105.379 1.00 110.41 ?  115 ILE A N   1 
ATOM   7253 C CA  . ILE E 5 115 ? 131.037 131.069 105.027 1.00 110.41 ?  115 ILE A CA  1 
ATOM   7254 C C   . ILE E 5 115 ? 130.052 130.844 106.171 1.00 110.41 ?  115 ILE A C   1 
ATOM   7255 O O   . ILE E 5 115 ? 129.266 131.736 106.525 1.00 110.41 ?  115 ILE A O   1 
ATOM   7256 C CB  . ILE E 5 115 ? 130.549 130.418 103.720 1.00 110.41 ?  115 ILE A CB  1 
ATOM   7257 C CG1 . ILE E 5 115 ? 131.232 131.065 102.516 1.00 110.41 ?  115 ILE A CG1 1 
ATOM   7258 C CG2 . ILE E 5 115 ? 129.040 130.523 103.597 1.00 110.41 ?  115 ILE A CG2 1 
ATOM   7259 C CD1 . ILE E 5 115 ? 130.733 130.550 101.188 1.00 110.41 ?  115 ILE A CD1 1 
ATOM   7260 N N   . ILE E 5 116 ? 130.087 129.652 106.771 1.00 107.90 ?  116 ILE A N   1 
ATOM   7261 C CA  . ILE E 5 116 ? 129.160 129.323 107.850 1.00 107.90 ?  116 ILE A CA  1 
ATOM   7262 C C   . ILE E 5 116 ? 129.379 130.242 109.044 1.00 107.90 ?  116 ILE A C   1 
ATOM   7263 O O   . ILE E 5 116 ? 128.422 130.731 109.652 1.00 107.90 ?  116 ILE A O   1 
ATOM   7264 C CB  . ILE E 5 116 ? 129.305 127.839 108.239 1.00 107.90 ?  116 ILE A CB  1 
ATOM   7265 C CG1 . ILE E 5 116 ? 128.598 126.949 107.216 1.00 107.90 ?  116 ILE A CG1 1 
ATOM   7266 C CG2 . ILE E 5 116 ? 128.754 127.590 109.632 1.00 107.90 ?  116 ILE A CG2 1 
ATOM   7267 C CD1 . ILE E 5 116 ? 127.105 127.177 107.137 1.00 107.90 ?  116 ILE A CD1 1 
ATOM   7268 N N   . PHE E 5 117 ? 130.640 130.500 109.394 1.00 108.92 ?  117 PHE A N   1 
ATOM   7269 C CA  . PHE E 5 117 ? 130.911 131.355 110.543 1.00 108.92 ?  117 PHE A CA  1 
ATOM   7270 C C   . PHE E 5 117 ? 130.635 132.821 110.233 1.00 108.92 ?  117 PHE A C   1 
ATOM   7271 O O   . PHE E 5 117 ? 130.249 133.575 111.132 1.00 108.92 ?  117 PHE A O   1 
ATOM   7272 C CB  . PHE E 5 117 ? 132.346 131.149 111.020 1.00 108.92 ?  117 PHE A CB  1 
ATOM   7273 C CG  . PHE E 5 117 ? 132.529 129.899 111.831 1.00 108.92 ?  117 PHE A CG  1 
ATOM   7274 C CD1 . PHE E 5 117 ? 131.819 129.712 113.004 1.00 108.92 ?  117 PHE A CD1 1 
ATOM   7275 C CD2 . PHE E 5 117 ? 133.396 128.904 111.414 1.00 108.92 ?  117 PHE A CD2 1 
ATOM   7276 C CE1 . PHE E 5 117 ? 131.976 128.562 113.749 1.00 108.92 ?  117 PHE A CE1 1 
ATOM   7277 C CE2 . PHE E 5 117 ? 133.556 127.752 112.155 1.00 108.92 ?  117 PHE A CE2 1 
ATOM   7278 C CZ  . PHE E 5 117 ? 132.844 127.580 113.324 1.00 108.92 ?  117 PHE A CZ  1 
ATOM   7279 N N   . LEU E 5 118 ? 130.797 133.239 108.975 1.00 105.05 ?  118 LEU A N   1 
ATOM   7280 C CA  . LEU E 5 118 ? 130.341 134.565 108.572 1.00 105.05 ?  118 LEU A CA  1 
ATOM   7281 C C   . LEU E 5 118 ? 128.844 134.712 108.813 1.00 105.05 ?  118 LEU A C   1 
ATOM   7282 O O   . LEU E 5 118 ? 128.383 135.701 109.398 1.00 105.05 ?  118 LEU A O   1 
ATOM   7283 C CB  . LEU E 5 118 ? 130.664 134.799 107.096 1.00 105.05 ?  118 LEU A CB  1 
ATOM   7284 C CG  . LEU E 5 118 ? 132.086 135.195 106.704 1.00 105.05 ?  118 LEU A CG  1 
ATOM   7285 C CD1 . LEU E 5 118 ? 132.249 135.121 105.196 1.00 105.05 ?  118 LEU A CD1 1 
ATOM   7286 C CD2 . LEU E 5 118 ? 132.416 136.579 107.204 1.00 105.05 ?  118 LEU A CD2 1 
ATOM   7287 N N   . THR E 5 119 ? 128.071 133.717 108.373 1.00 97.17  ?  119 THR A N   1 
ATOM   7288 C CA  . THR E 5 119 ? 126.625 133.752 108.571 1.00 97.17  ?  119 THR A CA  1 
ATOM   7289 C C   . THR E 5 119 ? 126.268 133.722 110.053 1.00 97.17  ?  119 THR A C   1 
ATOM   7290 O O   . THR E 5 119 ? 125.339 134.412 110.489 1.00 97.17  ?  119 THR A O   1 
ATOM   7291 C CB  . THR E 5 119 ? 125.974 132.584 107.831 1.00 97.17  ?  119 THR A CB  1 
ATOM   7292 O OG1 . THR E 5 119 ? 126.142 132.762 106.420 1.00 97.17  ?  119 THR A OG1 1 
ATOM   7293 C CG2 . THR E 5 119 ? 124.492 132.503 108.149 1.00 97.17  ?  119 THR A CG2 1 
ATOM   7294 N N   . VAL E 5 120 ? 126.997 132.931 110.841 1.00 97.18  ?  120 VAL A N   1 
ATOM   7295 C CA  . VAL E 5 120 ? 126.727 132.849 112.273 1.00 97.18  ?  120 VAL A CA  1 
ATOM   7296 C C   . VAL E 5 120 ? 127.008 134.184 112.952 1.00 97.18  ?  120 VAL A C   1 
ATOM   7297 O O   . VAL E 5 120 ? 126.247 134.622 113.821 1.00 97.18  ?  120 VAL A O   1 
ATOM   7298 C CB  . VAL E 5 120 ? 127.541 131.704 112.901 1.00 97.18  ?  120 VAL A CB  1 
ATOM   7299 C CG1 . VAL E 5 120 ? 127.621 131.867 114.411 1.00 97.18  ?  120 VAL A CG1 1 
ATOM   7300 C CG2 . VAL E 5 120 ? 126.918 130.371 112.542 1.00 97.18  ?  120 VAL A CG2 1 
ATOM   7301 N N   . VAL E 5 121 ? 128.101 134.850 112.574 1.00 95.75  ?  121 VAL A N   1 
ATOM   7302 C CA  . VAL E 5 121 ? 128.402 136.165 113.135 1.00 95.75  ?  121 VAL A CA  1 
ATOM   7303 C C   . VAL E 5 121 ? 127.322 137.168 112.749 1.00 95.75  ?  121 VAL A C   1 
ATOM   7304 O O   . VAL E 5 121 ? 126.896 137.992 113.570 1.00 95.75  ?  121 VAL A O   1 
ATOM   7305 C CB  . VAL E 5 121 ? 129.801 136.629 112.685 1.00 95.75  ?  121 VAL A CB  1 
ATOM   7306 C CG1 . VAL E 5 121 ? 129.978 138.113 112.941 1.00 95.75  ?  121 VAL A CG1 1 
ATOM   7307 C CG2 . VAL E 5 121 ? 130.876 135.834 113.405 1.00 95.75  ?  121 VAL A CG2 1 
ATOM   7308 N N   . ALA E 5 122 ? 126.862 137.116 111.496 1.00 90.32  ?  122 ALA A N   1 
ATOM   7309 C CA  . ALA E 5 122 ? 125.791 138.013 111.070 1.00 90.32  ?  122 ALA A CA  1 
ATOM   7310 C C   . ALA E 5 122 ? 124.517 137.778 111.875 1.00 90.32  ?  122 ALA A C   1 
ATOM   7311 O O   . ALA E 5 122 ? 123.854 138.732 112.297 1.00 90.32  ?  122 ALA A O   1 
ATOM   7312 C CB  . ALA E 5 122 ? 125.522 137.840 109.576 1.00 90.32  ?  122 ALA A CB  1 
ATOM   7313 N N   . VAL E 5 123 ? 124.165 136.512 112.103 1.00 87.61  ?  123 VAL A N   1 
ATOM   7314 C CA  . VAL E 5 123 ? 122.967 136.196 112.877 1.00 87.61  ?  123 VAL A CA  1 
ATOM   7315 C C   . VAL E 5 123 ? 123.132 136.638 114.326 1.00 87.61  ?  123 VAL A C   1 
ATOM   7316 O O   . VAL E 5 123 ? 122.183 137.125 114.955 1.00 87.61  ?  123 VAL A O   1 
ATOM   7317 C CB  . VAL E 5 123 ? 122.649 134.694 112.768 1.00 87.61  ?  123 VAL A CB  1 
ATOM   7318 C CG1 . VAL E 5 123 ? 121.654 134.271 113.836 1.00 87.61  ?  123 VAL A CG1 1 
ATOM   7319 C CG2 . VAL E 5 123 ? 122.111 134.371 111.386 1.00 87.61  ?  123 VAL A CG2 1 
ATOM   7320 N N   . ASP E 5 124 ? 124.334 136.474 114.881 1.00 90.29  ?  124 ASP A N   1 
ATOM   7321 C CA  . ASP E 5 124 ? 124.593 136.923 116.244 1.00 90.29  ?  124 ASP A CA  1 
ATOM   7322 C C   . ASP E 5 124 ? 124.414 138.429 116.363 1.00 90.29  ?  124 ASP A C   1 
ATOM   7323 O O   . ASP E 5 124 ? 123.795 138.920 117.314 1.00 90.29  ?  124 ASP A O   1 
ATOM   7324 C CB  . ASP E 5 124 ? 126.002 136.510 116.671 1.00 90.29  ?  124 ASP A CB  1 
ATOM   7325 C CG  . ASP E 5 124 ? 126.326 136.930 118.089 1.00 90.29  ?  124 ASP A CG  1 
ATOM   7326 O OD1 . ASP E 5 124 ? 125.403 136.949 118.930 1.00 90.29  ?  124 ASP A OD1 1 
ATOM   7327 O OD2 . ASP E 5 124 ? 127.504 137.239 118.365 1.00 90.29  -1 124 ASP A OD2 1 
ATOM   7328 N N   . ARG E 5 125 ? 124.969 139.153 115.377 1.00 88.48  ?  125 ARG A N   1 
ATOM   7329 C CA  . ARG E 5 125 ? 124.860 140.611 115.322 1.00 88.48  ?  125 ARG A CA  1 
ATOM   7330 C C   . ARG E 5 125 ? 123.384 141.037 115.134 1.00 88.48  ?  125 ARG A C   1 
ATOM   7331 O O   . ARG E 5 125 ? 122.986 142.043 115.680 1.00 88.48  ?  125 ARG A O   1 
ATOM   7332 C CB  . ARG E 5 125 ? 125.812 141.206 114.218 1.00 88.48  ?  125 ARG A CB  1 
ATOM   7333 C CG  . ARG E 5 125 ? 127.356 140.931 114.288 1.00 88.48  ?  125 ARG A CG  1 
ATOM   7334 C CD  . ARG E 5 125 ? 128.273 141.287 113.048 1.00 88.48  ?  125 ARG A CD  1 
ATOM   7335 N NE  . ARG E 5 125 ? 129.680 141.587 113.450 1.00 88.48  ?  125 ARG A NE  1 
ATOM   7336 C CZ  . ARG E 5 125 ? 130.825 141.704 112.723 1.00 88.48  ?  125 ARG A CZ  1 
ATOM   7337 N NH1 . ARG E 5 125 ? 130.983 141.564 111.379 1.00 88.48  1  125 ARG A NH1 1 
ATOM   7338 N NH2 . ARG E 5 125 ? 131.921 141.981 113.411 1.00 88.48  1  125 ARG A NH2 1 
ATOM   7339 N N   . TYR E 5 126 ? 122.567 140.292 114.390 1.00 85.39  ?  126 TYR A N   1 
ATOM   7340 C CA  . TYR E 5 126 ? 121.150 140.585 114.196 1.00 85.39  ?  126 TYR A CA  1 
ATOM   7341 C C   . TYR E 5 126 ? 120.356 140.355 115.476 1.00 85.39  ?  126 TYR A C   1 
ATOM   7342 O O   . TYR E 5 126 ? 119.489 141.161 115.829 1.00 85.39  ?  126 TYR A O   1 
ATOM   7343 C CB  . TYR E 5 126 ? 120.594 139.748 113.044 1.00 85.39  ?  126 TYR A CB  1 
ATOM   7344 C CG  . TYR E 5 126 ? 119.085 139.646 113.013 1.00 85.39  ?  126 TYR A CG  1 
ATOM   7345 C CD1 . TYR E 5 126 ? 118.314 140.652 112.456 1.00 85.39  ?  126 TYR A CD1 1 
ATOM   7346 C CD2 . TYR E 5 126 ? 118.437 138.526 113.505 1.00 85.39  ?  126 TYR A CD2 1 
ATOM   7347 C CE1 . TYR E 5 126 ? 116.937 140.557 112.420 1.00 85.39  ?  126 TYR A CE1 1 
ATOM   7348 C CE2 . TYR E 5 126 ? 117.061 138.422 113.473 1.00 85.39  ?  126 TYR A CE2 1 
ATOM   7349 C CZ  . TYR E 5 126 ? 116.317 139.440 112.927 1.00 85.39  ?  126 TYR A CZ  1 
ATOM   7350 O OH  . TYR E 5 126 ? 114.945 139.344 112.887 1.00 85.39  ?  126 TYR A OH  1 
ATOM   7351 N N   . PHE E 5 127 ? 120.638 139.262 116.189 1.00 86.12  ?  127 PHE A N   1 
ATOM   7352 C CA  . PHE E 5 127 ? 119.985 139.046 117.478 1.00 86.12  ?  127 PHE A CA  1 
ATOM   7353 C C   . PHE E 5 127 ? 120.425 140.064 118.521 1.00 86.12  ?  127 PHE A C   1 
ATOM   7354 O O   . PHE E 5 127 ? 119.624 140.447 119.379 1.00 86.12  ?  127 PHE A O   1 
ATOM   7355 C CB  . PHE E 5 127 ? 120.246 137.628 117.986 1.00 86.12  ?  127 PHE A CB  1 
ATOM   7356 C CG  . PHE E 5 127 ? 119.566 136.556 117.185 1.00 86.12  ?  127 PHE A CG  1 
ATOM   7357 C CD1 . PHE E 5 127 ? 118.552 136.868 116.301 1.00 86.12  ?  127 PHE A CD1 1 
ATOM   7358 C CD2 . PHE E 5 127 ? 119.945 135.235 117.315 1.00 86.12  ?  127 PHE A CD2 1 
ATOM   7359 C CE1 . PHE E 5 127 ? 117.922 135.880 115.568 1.00 86.12  ?  127 PHE A CE1 1 
ATOM   7360 C CE2 . PHE E 5 127 ? 119.323 134.244 116.582 1.00 86.12  ?  127 PHE A CE2 1 
ATOM   7361 C CZ  . PHE E 5 127 ? 118.311 134.568 115.707 1.00 86.12  ?  127 PHE A CZ  1 
ATOM   7362 N N   . ARG E 5 128 ? 121.650 140.555 118.447 1.00 85.10  ?  128 ARG A N   1 
ATOM   7363 C CA  . ARG E 5 128 ? 122.166 141.498 119.433 1.00 85.10  ?  128 ARG A CA  1 
ATOM   7364 C C   . ARG E 5 128 ? 121.630 142.885 119.231 1.00 85.10  ?  128 ARG A C   1 
ATOM   7365 O O   . ARG E 5 128 ? 121.580 143.667 120.161 1.00 85.10  ?  128 ARG A O   1 
ATOM   7366 C CB  . ARG E 5 128 ? 123.678 141.559 119.339 1.00 85.10  ?  128 ARG A CB  1 
ATOM   7367 C CG  . ARG E 5 128 ? 124.397 140.934 120.511 1.00 85.10  ?  128 ARG A CG  1 
ATOM   7368 C CD  . ARG E 5 128 ? 125.397 139.903 120.035 1.00 85.10  ?  128 ARG A CD  1 
ATOM   7369 N NE  . ARG E 5 128 ? 125.767 138.987 121.103 1.00 85.10  ?  128 ARG A NE  1 
ATOM   7370 C CZ  . ARG E 5 128 ? 126.574 139.307 122.105 1.00 85.10  ?  128 ARG A CZ  1 
ATOM   7371 N NH1 . ARG E 5 128 ? 127.098 140.520 122.169 1.00 85.10  1  128 ARG A NH1 1 
ATOM   7372 N NH2 . ARG E 5 128 ? 126.859 138.414 123.040 1.00 85.10  1  128 ARG A NH2 1 
ATOM   7373 N N   . VAL E 5 129 ? 121.236 143.201 118.015 1.00 80.87  ?  129 VAL A N   1 
ATOM   7374 C CA  . VAL E 5 129 ? 120.725 144.530 117.688 1.00 80.87  ?  129 VAL A CA  1 
ATOM   7375 C C   . VAL E 5 129 ? 119.201 144.571 117.689 1.00 80.87  ?  129 VAL A C   1 
ATOM   7376 O O   . VAL E 5 129 ? 118.598 145.442 118.315 1.00 80.87  ?  129 VAL A O   1 
ATOM   7377 C CB  . VAL E 5 129 ? 121.295 145.006 116.334 1.00 80.87  ?  129 VAL A CB  1 
ATOM   7378 C CG1 . VAL E 5 129 ? 120.590 146.270 115.881 1.00 80.87  ?  129 VAL A CG1 1 
ATOM   7379 C CG2 . VAL E 5 129 ? 122.787 145.246 116.449 1.00 80.87  ?  129 VAL A CG2 1 
ATOM   7380 N N   . VAL E 5 130 ? 118.556 143.636 116.990 1.00 83.18  ?  130 VAL A N   1 
ATOM   7381 C CA  . VAL E 5 130 ? 117.106 143.703 116.833 1.00 83.18  ?  130 VAL A CA  1 
ATOM   7382 C C   . VAL E 5 130 ? 116.382 143.176 118.068 1.00 83.18  ?  130 VAL A C   1 
ATOM   7383 O O   . VAL E 5 130 ? 115.314 143.685 118.428 1.00 83.18  ?  130 VAL A O   1 
ATOM   7384 C CB  . VAL E 5 130 ? 116.682 142.946 115.564 1.00 83.18  ?  130 VAL A CB  1 
ATOM   7385 C CG1 . VAL E 5 130 ? 115.174 143.015 115.374 1.00 83.18  ?  130 VAL A CG1 1 
ATOM   7386 C CG2 . VAL E 5 130 ? 117.397 143.518 114.354 1.00 83.18  ?  130 VAL A CG2 1 
ATOM   7387 N N   . HIS E 5 131 ? 116.940 142.176 118.745 1.00 85.96  ?  131 HIS A N   1 
ATOM   7388 C CA  . HIS E 5 131 ? 116.333 141.588 119.938 1.00 85.96  ?  131 HIS A CA  1 
ATOM   7389 C C   . HIS E 5 131 ? 117.354 141.604 121.068 1.00 85.96  ?  131 HIS A C   1 
ATOM   7390 O O   . HIS E 5 131 ? 117.874 140.557 121.471 1.00 85.96  ?  131 HIS A O   1 
ATOM   7391 C CB  . HIS E 5 131 ? 115.843 140.166 119.662 1.00 85.96  ?  131 HIS A CB  1 
ATOM   7392 C CG  . HIS E 5 131 ? 115.055 140.032 118.397 1.00 85.96  ?  131 HIS A CG  1 
ATOM   7393 N ND1 . HIS E 5 131 ? 113.934 140.662 117.973 1.00 85.96  ?  131 HIS A ND1 1 
ATOM   7394 C CD2 . HIS E 5 131 ? 115.406 139.158 117.391 1.00 85.96  ?  131 HIS A CD2 1 
ATOM   7395 C CE1 . HIS E 5 131 ? 113.632 140.160 116.730 1.00 85.96  ?  131 HIS A CE1 1 
ATOM   7396 N NE2 . HIS E 5 131 ? 114.536 139.255 116.402 1.00 85.96  ?  131 HIS A NE2 1 
ATOM   7397 N N   . PRO E 5 132 ? 117.657 142.787 121.610 1.00 80.84  ?  132 PRO A N   1 
ATOM   7398 C CA  . PRO E 5 132 ? 118.727 142.877 122.616 1.00 80.84  ?  132 PRO A CA  1 
ATOM   7399 C C   . PRO E 5 132 ? 118.453 142.081 123.879 1.00 80.84  ?  132 PRO A C   1 
ATOM   7400 O O   . PRO E 5 132 ? 119.403 141.676 124.560 1.00 80.84  ?  132 PRO A O   1 
ATOM   7401 C CB  . PRO E 5 132 ? 118.808 144.383 122.903 1.00 80.84  ?  132 PRO A CB  1 
ATOM   7402 C CG  . PRO E 5 132 ? 117.470 144.914 122.529 1.00 80.84  ?  132 PRO A CG  1 
ATOM   7403 C CD  . PRO E 5 132 ? 116.998 144.083 121.379 1.00 80.84  ?  132 PRO A CD  1 
ATOM   7404 N N   . HIS E 5 133 ? 117.189 141.844 124.217 1.00 81.98  ?  133 HIS A N   1 
ATOM   7405 C CA  . HIS E 5 133 ? 116.838 141.119 125.430 1.00 81.98  ?  133 HIS A CA  1 
ATOM   7406 C C   . HIS E 5 133 ? 116.707 139.618 125.214 1.00 81.98  ?  133 HIS A C   1 
ATOM   7407 O O   . HIS E 5 133 ? 116.365 138.901 126.159 1.00 81.98  ?  133 HIS A O   1 
ATOM   7408 C CB  . HIS E 5 133 ? 115.533 141.665 126.012 1.00 81.98  ?  133 HIS A CB  1 
ATOM   7409 C CG  . HIS E 5 133 ? 115.512 143.154 126.145 1.00 81.98  ?  133 HIS A CG  1 
ATOM   7410 N ND1 . HIS E 5 133 ? 116.499 143.856 126.803 1.00 81.98  ?  133 HIS A ND1 1 
ATOM   7411 C CD2 . HIS E 5 133 ? 114.624 144.076 125.705 1.00 81.98  ?  133 HIS A CD2 1 
ATOM   7412 C CE1 . HIS E 5 133 ? 116.220 145.146 126.761 1.00 81.98  ?  133 HIS A CE1 1 
ATOM   7413 N NE2 . HIS E 5 133 ? 115.087 145.306 126.102 1.00 81.98  ?  133 HIS A NE2 1 
ATOM   7414 N N   . HIS E 5 134 ? 116.959 139.130 124.002 1.00 91.17  ?  134 HIS A N   1 
ATOM   7415 C CA  . HIS E 5 134 ? 116.901 137.697 123.753 1.00 91.17  ?  134 HIS A CA  1 
ATOM   7416 C C   . HIS E 5 134 ? 117.983 136.981 124.551 1.00 91.17  ?  134 HIS A C   1 
ATOM   7417 O O   . HIS E 5 134 ? 119.122 137.446 124.641 1.00 91.17  ?  134 HIS A O   1 
ATOM   7418 C CB  . HIS E 5 134 ? 117.065 137.415 122.260 1.00 91.17  ?  134 HIS A CB  1 
ATOM   7419 C CG  . HIS E 5 134 ? 116.455 136.121 121.819 1.00 91.17  ?  134 HIS A CG  1 
ATOM   7420 N ND1 . HIS E 5 134 ? 116.981 134.895 122.163 1.00 91.17  ?  134 HIS A ND1 1 
ATOM   7421 C CD2 . HIS E 5 134 ? 115.363 135.863 121.062 1.00 91.17  ?  134 HIS A CD2 1 
ATOM   7422 C CE1 . HIS E 5 134 ? 116.240 133.937 121.636 1.00 91.17  ?  134 HIS A CE1 1 
ATOM   7423 N NE2 . HIS E 5 134 ? 115.251 134.498 120.963 1.00 91.17  ?  134 HIS A NE2 1 
ATOM   7424 N N   . ALA E 5 135 ? 117.616 135.840 125.138 1.00 94.74  ?  135 ALA A N   1 
ATOM   7425 C CA  . ALA E 5 135 ? 118.553 135.102 125.977 1.00 94.74  ?  135 ALA A CA  1 
ATOM   7426 C C   . ALA E 5 135 ? 119.735 134.559 125.189 1.00 94.74  ?  135 ALA A C   1 
ATOM   7427 O O   . ALA E 5 135 ? 120.808 134.349 125.767 1.00 94.74  ?  135 ALA A O   1 
ATOM   7428 C CB  . ALA E 5 135 ? 117.832 133.956 126.688 1.00 94.74  ?  135 ALA A CB  1 
ATOM   7429 N N   . LEU E 5 136 ? 119.571 134.339 123.882 1.00 94.57  ?  136 LEU A N   1 
ATOM   7430 C CA  . LEU E 5 136 ? 120.665 133.797 123.083 1.00 94.57  ?  136 LEU A CA  1 
ATOM   7431 C C   . LEU E 5 136 ? 121.830 134.776 122.999 1.00 94.57  ?  136 LEU A C   1 
ATOM   7432 O O   . LEU E 5 136 ? 122.959 134.375 122.692 1.00 94.57  ?  136 LEU A O   1 
ATOM   7433 C CB  . LEU E 5 136 ? 120.154 133.428 121.688 1.00 94.57  ?  136 LEU A CB  1 
ATOM   7434 C CG  . LEU E 5 136 ? 121.129 132.778 120.707 1.00 94.57  ?  136 LEU A CG  1 
ATOM   7435 C CD1 . LEU E 5 136 ? 121.606 131.445 121.243 1.00 94.57  ?  136 LEU A CD1 1 
ATOM   7436 C CD2 . LEU E 5 136 ? 120.459 132.573 119.372 1.00 94.57  ?  136 LEU A CD2 1 
ATOM   7437 N N   . ASN E 5 137 ? 121.583 136.056 123.285 1.00 91.61  ?  137 ASN A N   1 
ATOM   7438 C CA  . ASN E 5 137 ? 122.655 137.041 123.340 1.00 91.61  ?  137 ASN A CA  1 
ATOM   7439 C C   . ASN E 5 137 ? 123.553 136.871 124.558 1.00 91.61  ?  137 ASN A C   1 
ATOM   7440 O O   . ASN E 5 137 ? 124.603 137.518 124.622 1.00 91.61  ?  137 ASN A O   1 
ATOM   7441 C CB  . ASN E 5 137 ? 122.071 138.455 123.332 1.00 91.61  ?  137 ASN A CB  1 
ATOM   7442 C CG  . ASN E 5 137 ? 121.206 138.722 122.118 1.00 91.61  ?  137 ASN A CG  1 
ATOM   7443 O OD1 . ASN E 5 137 ? 121.582 138.402 120.992 1.00 91.61  ?  137 ASN A OD1 1 
ATOM   7444 N ND2 . ASN E 5 137 ? 120.040 139.314 122.342 1.00 91.61  ?  137 ASN A ND2 1 
ATOM   7445 N N   . LYS E 5 138 ? 123.175 136.029 125.517 1.00 98.16  ?  138 LYS A N   1 
ATOM   7446 C CA  . LYS E 5 138 ? 123.942 135.840 126.743 1.00 98.16  ?  138 LYS A CA  1 
ATOM   7447 C C   . LYS E 5 138 ? 124.256 134.368 126.967 1.00 98.16  ?  138 LYS A C   1 
ATOM   7448 O O   . LYS E 5 138 ? 124.140 133.850 128.081 1.00 98.16  ?  138 LYS A O   1 
ATOM   7449 C CB  . LYS E 5 138 ? 123.201 136.419 127.946 1.00 98.16  ?  138 LYS A CB  1 
ATOM   7450 C CG  . LYS E 5 138 ? 123.046 137.929 127.911 1.00 98.16  ?  138 LYS A CG  1 
ATOM   7451 C CD  . LYS E 5 138 ? 122.320 138.435 129.144 1.00 98.16  ?  138 LYS A CD  1 
ATOM   7452 C CE  . LYS E 5 138 ? 122.052 139.928 129.051 1.00 98.16  ?  138 LYS A CE  1 
ATOM   7453 N NZ  . LYS E 5 138 ? 123.314 140.717 129.026 1.00 98.16  1  138 LYS A NZ  1 
ATOM   7454 N N   . ILE E 5 139 ? 124.660 133.671 125.911 1.00 107.35 ?  139 ILE A N   1 
ATOM   7455 C CA  . ILE E 5 139 ? 125.023 132.264 126.026 1.00 107.35 ?  139 ILE A CA  1 
ATOM   7456 C C   . ILE E 5 139 ? 126.440 132.143 126.567 1.00 107.35 ?  139 ILE A C   1 
ATOM   7457 O O   . ILE E 5 139 ? 127.304 132.991 126.314 1.00 107.35 ?  139 ILE A O   1 
ATOM   7458 C CB  . ILE E 5 139 ? 124.872 131.547 124.671 1.00 107.35 ?  139 ILE A CB  1 
ATOM   7459 C CG1 . ILE E 5 139 ? 125.633 132.300 123.578 1.00 107.35 ?  139 ILE A CG1 1 
ATOM   7460 C CG2 . ILE E 5 139 ? 123.407 131.401 124.314 1.00 107.35 ?  139 ILE A CG2 1 
ATOM   7461 C CD1 . ILE E 5 139 ? 125.604 131.612 122.232 1.00 107.35 ?  139 ILE A CD1 1 
ATOM   7462 N N   . SER E 5 140 ? 126.681 131.075 127.322 1.00 120.52 ?  140 SER A N   1 
ATOM   7463 C CA  . SER E 5 140 ? 127.985 130.856 127.927 1.00 120.52 ?  140 SER A CA  1 
ATOM   7464 C C   . SER E 5 140 ? 129.018 130.481 126.868 1.00 120.52 ?  140 SER A C   1 
ATOM   7465 O O   . SER E 5 140 ? 128.688 130.112 125.737 1.00 120.52 ?  140 SER A O   1 
ATOM   7466 C CB  . SER E 5 140 ? 127.906 129.761 128.990 1.00 120.52 ?  140 SER A CB  1 
ATOM   7467 O OG  . SER E 5 140 ? 129.201 129.371 129.415 1.00 120.52 ?  140 SER A OG  1 
ATOM   7468 N N   . ASN E 5 141 ? 130.292 130.587 127.254 1.00 123.00 ?  141 ASN A N   1 
ATOM   7469 C CA  . ASN E 5 141 ? 131.375 130.238 126.340 1.00 123.00 ?  141 ASN A CA  1 
ATOM   7470 C C   . ASN E 5 141 ? 131.326 128.763 125.964 1.00 123.00 ?  141 ASN A C   1 
ATOM   7471 O O   . ASN E 5 141 ? 131.687 128.389 124.842 1.00 123.00 ?  141 ASN A O   1 
ATOM   7472 C CB  . ASN E 5 141 ? 132.723 130.588 126.968 1.00 123.00 ?  141 ASN A CB  1 
ATOM   7473 C CG  . ASN E 5 141 ? 133.000 132.077 126.960 1.00 123.00 ?  141 ASN A CG  1 
ATOM   7474 O OD1 . ASN E 5 141 ? 133.737 132.578 126.111 1.00 123.00 ?  141 ASN A OD1 1 
ATOM   7475 N ND2 . ASN E 5 141 ? 132.408 132.795 127.907 1.00 123.00 ?  141 ASN A ND2 1 
ATOM   7476 N N   . TRP E 5 142 ? 130.890 127.909 126.892 1.00 129.48 ?  142 TRP A N   1 
ATOM   7477 C CA  . TRP E 5 142 ? 130.744 126.491 126.579 1.00 129.48 ?  142 TRP A CA  1 
ATOM   7478 C C   . TRP E 5 142 ? 129.699 126.272 125.493 1.00 129.48 ?  142 TRP A C   1 
ATOM   7479 O O   . TRP E 5 142 ? 129.890 125.443 124.596 1.00 129.48 ?  142 TRP A O   1 
ATOM   7480 C CB  . TRP E 5 142 ? 130.382 125.708 127.840 1.00 129.48 ?  142 TRP A CB  1 
ATOM   7481 C CG  . TRP E 5 142 ? 130.550 124.228 127.692 1.00 129.48 ?  142 TRP A CG  1 
ATOM   7482 C CD1 . TRP E 5 142 ? 131.692 123.562 127.354 1.00 129.48 ?  142 TRP A CD1 1 
ATOM   7483 C CD2 . TRP E 5 142 ? 129.542 123.227 127.878 1.00 129.48 ?  142 TRP A CD2 1 
ATOM   7484 N NE1 . TRP E 5 142 ? 131.458 122.209 127.317 1.00 129.48 ?  142 TRP A NE1 1 
ATOM   7485 C CE2 . TRP E 5 142 ? 130.146 121.977 127.635 1.00 129.48 ?  142 TRP A CE2 1 
ATOM   7486 C CE3 . TRP E 5 142 ? 128.189 123.266 128.226 1.00 129.48 ?  142 TRP A CE3 1 
ATOM   7487 C CZ2 . TRP E 5 142 ? 129.442 120.778 127.729 1.00 129.48 ?  142 TRP A CZ2 1 
ATOM   7488 C CZ3 . TRP E 5 142 ? 127.492 122.075 128.318 1.00 129.48 ?  142 TRP A CZ3 1 
ATOM   7489 C CH2 . TRP E 5 142 ? 128.120 120.848 128.071 1.00 129.48 ?  142 TRP A CH2 1 
ATOM   7490 N N   . THR E 5 143 ? 128.585 127.005 125.560 1.00 124.90 ?  143 THR A N   1 
ATOM   7491 C CA  . THR E 5 143 ? 127.566 126.894 124.521 1.00 124.90 ?  143 THR A CA  1 
ATOM   7492 C C   . THR E 5 143 ? 128.113 127.334 123.169 1.00 124.90 ?  143 THR A C   1 
ATOM   7493 O O   . THR E 5 143 ? 127.837 126.702 122.143 1.00 124.90 ?  143 THR A O   1 
ATOM   7494 C CB  . THR E 5 143 ? 126.337 127.721 124.896 1.00 124.90 ?  143 THR A CB  1 
ATOM   7495 O OG1 . THR E 5 143 ? 125.982 127.462 126.260 1.00 124.90 ?  143 THR A OG1 1 
ATOM   7496 C CG2 . THR E 5 143 ? 125.163 127.365 123.997 1.00 124.90 ?  143 THR A CG2 1 
ATOM   7497 N N   . ALA E 5 144 ? 128.893 128.417 123.150 1.00 123.68 ?  144 ALA A N   1 
ATOM   7498 C CA  . ALA E 5 144 ? 129.500 128.870 121.904 1.00 123.68 ?  144 ALA A CA  1 
ATOM   7499 C C   . ALA E 5 144 ? 130.473 127.835 121.355 1.00 123.68 ?  144 ALA A C   1 
ATOM   7500 O O   . ALA E 5 144 ? 130.529 127.608 120.142 1.00 123.68 ?  144 ALA A O   1 
ATOM   7501 C CB  . ALA E 5 144 ? 130.201 130.211 122.117 1.00 123.68 ?  144 ALA A CB  1 
ATOM   7502 N N   . ALA E 5 145 ? 131.254 127.201 122.233 1.00 125.15 ?  145 ALA A N   1 
ATOM   7503 C CA  . ALA E 5 145 ? 132.175 126.159 121.786 1.00 125.15 ?  145 ALA A CA  1 
ATOM   7504 C C   . ALA E 5 145 ? 131.423 124.963 121.215 1.00 125.15 ?  145 ALA A C   1 
ATOM   7505 O O   . ALA E 5 145 ? 131.834 124.386 120.201 1.00 125.15 ?  145 ALA A O   1 
ATOM   7506 C CB  . ALA E 5 145 ? 133.078 125.726 122.940 1.00 125.15 ?  145 ALA A CB  1 
ATOM   7507 N N   . ILE E 5 146 ? 130.319 124.571 121.858 1.00 125.46 ?  146 ILE A N   1 
ATOM   7508 C CA  . ILE E 5 146 ? 129.508 123.472 121.341 1.00 125.46 ?  146 ILE A CA  1 
ATOM   7509 C C   . ILE E 5 146 ? 128.936 123.828 119.975 1.00 125.46 ?  146 ILE A C   1 
ATOM   7510 O O   . ILE E 5 146 ? 128.929 123.003 119.055 1.00 125.46 ?  146 ILE A O   1 
ATOM   7511 C CB  . ILE E 5 146 ? 128.395 123.103 122.340 1.00 125.46 ?  146 ILE A CB  1 
ATOM   7512 C CG1 . ILE E 5 146 ? 128.996 122.595 123.650 1.00 125.46 ?  146 ILE A CG1 1 
ATOM   7513 C CG2 . ILE E 5 146 ? 127.460 122.062 121.742 1.00 125.46 ?  146 ILE A CG2 1 
ATOM   7514 C CD1 . ILE E 5 146 ? 127.986 122.458 124.765 1.00 125.46 ?  146 ILE A CD1 1 
ATOM   7515 N N   . ILE E 5 147 ? 128.447 125.061 119.823 1.00 123.88 ?  147 ILE A N   1 
ATOM   7516 C CA  . ILE E 5 147 ? 127.907 125.494 118.537 1.00 123.88 ?  147 ILE A CA  1 
ATOM   7517 C C   . ILE E 5 147 ? 128.994 125.482 117.470 1.00 123.88 ?  147 ILE A C   1 
ATOM   7518 O O   . ILE E 5 147 ? 128.760 125.065 116.330 1.00 123.88 ?  147 ILE A O   1 
ATOM   7519 C CB  . ILE E 5 147 ? 127.254 126.883 118.669 1.00 123.88 ?  147 ILE A CB  1 
ATOM   7520 C CG1 . ILE E 5 147 ? 126.014 126.805 119.562 1.00 123.88 ?  147 ILE A CG1 1 
ATOM   7521 C CG2 . ILE E 5 147 ? 126.888 127.439 117.302 1.00 123.88 ?  147 ILE A CG2 1 
ATOM   7522 C CD1 . ILE E 5 147 ? 125.485 128.155 119.988 1.00 123.88 ?  147 ILE A CD1 1 
ATOM   7523 N N   . SER E 5 148 ? 130.197 125.942 117.820 1.00 123.69 ?  148 SER A N   1 
ATOM   7524 C CA  . SER E 5 148 ? 131.300 125.945 116.864 1.00 123.69 ?  148 SER A CA  1 
ATOM   7525 C C   . SER E 5 148 ? 131.666 124.531 116.435 1.00 123.69 ?  148 SER A C   1 
ATOM   7526 O O   . SER E 5 148 ? 131.865 124.268 115.242 1.00 123.69 ?  148 SER A O   1 
ATOM   7527 C CB  . SER E 5 148 ? 132.512 126.649 117.469 1.00 123.69 ?  148 SER A CB  1 
ATOM   7528 O OG  . SER E 5 148 ? 132.208 127.989 117.811 1.00 123.69 ?  148 SER A OG  1 
ATOM   7529 N N   . CYS E 5 149 ? 131.761 123.606 117.393 1.00 127.13 ?  149 CYS A N   1 
ATOM   7530 C CA  . CYS E 5 149 ? 132.070 122.221 117.056 1.00 127.13 ?  149 CYS A CA  1 
ATOM   7531 C C   . CYS E 5 149 ? 130.977 121.612 116.187 1.00 127.13 ?  149 CYS A C   1 
ATOM   7532 O O   . CYS E 5 149 ? 131.264 120.878 115.236 1.00 127.13 ?  149 CYS A O   1 
ATOM   7533 C CB  . CYS E 5 149 ? 132.267 121.399 118.330 1.00 127.13 ?  149 CYS A CB  1 
ATOM   7534 S SG  . CYS E 5 149 ? 133.699 121.888 119.317 1.00 127.13 ?  149 CYS A SG  1 
ATOM   7535 N N   . LEU E 5 150 ? 129.716 121.917 116.494 1.00 126.54 ?  150 LEU A N   1 
ATOM   7536 C CA  . LEU E 5 150 ? 128.609 121.417 115.687 1.00 126.54 ?  150 LEU A CA  1 
ATOM   7537 C C   . LEU E 5 150 ? 128.680 121.946 114.257 1.00 126.54 ?  150 LEU A C   1 
ATOM   7538 O O   . LEU E 5 150 ? 128.527 121.179 113.297 1.00 126.54 ?  150 LEU A O   1 
ATOM   7539 C CB  . LEU E 5 150 ? 127.291 121.787 116.374 1.00 126.54 ?  150 LEU A CB  1 
ATOM   7540 C CG  . LEU E 5 150 ? 125.921 121.297 115.907 1.00 126.54 ?  150 LEU A CG  1 
ATOM   7541 C CD1 . LEU E 5 150 ? 124.989 121.221 117.097 1.00 126.54 ?  150 LEU A CD1 1 
ATOM   7542 C CD2 . LEU E 5 150 ? 125.346 122.269 114.907 1.00 126.54 ?  150 LEU A CD2 1 
ATOM   7543 N N   . LEU E 5 151 ? 128.947 123.244 114.093 1.00 124.08 ?  151 LEU A N   1 
ATOM   7544 C CA  . LEU E 5 151 ? 129.065 123.816 112.754 1.00 124.08 ?  151 LEU A CA  1 
ATOM   7545 C C   . LEU E 5 151 ? 130.233 123.201 111.994 1.00 124.08 ?  151 LEU A C   1 
ATOM   7546 O O   . LEU E 5 151 ? 130.120 122.917 110.794 1.00 124.08 ?  151 LEU A O   1 
ATOM   7547 C CB  . LEU E 5 151 ? 129.223 125.332 112.841 1.00 124.08 ?  151 LEU A CB  1 
ATOM   7548 C CG  . LEU E 5 151 ? 128.045 126.096 113.445 1.00 124.08 ?  151 LEU A CG  1 
ATOM   7549 C CD1 . LEU E 5 151 ? 128.497 127.468 113.907 1.00 124.08 ?  151 LEU A CD1 1 
ATOM   7550 C CD2 . LEU E 5 151 ? 126.898 126.204 112.454 1.00 124.08 ?  151 LEU A CD2 1 
ATOM   7551 N N   . TRP E 5 152 ? 131.364 122.996 112.675 1.00 123.68 ?  152 TRP A N   1 
ATOM   7552 C CA  . TRP E 5 152 ? 132.462 122.248 112.074 1.00 123.68 ?  152 TRP A CA  1 
ATOM   7553 C C   . TRP E 5 152 ? 131.995 120.864 111.646 1.00 123.68 ?  152 TRP A C   1 
ATOM   7554 O O   . TRP E 5 152 ? 132.439 120.337 110.620 1.00 123.68 ?  152 TRP A O   1 
ATOM   7555 C CB  . TRP E 5 152 ? 133.626 122.135 113.058 1.00 123.68 ?  152 TRP A CB  1 
ATOM   7556 C CG  . TRP E 5 152 ? 134.482 123.363 113.161 1.00 123.68 ?  152 TRP A CG  1 
ATOM   7557 C CD1 . TRP E 5 152 ? 134.660 124.144 114.265 1.00 123.68 ?  152 TRP A CD1 1 
ATOM   7558 C CD2 . TRP E 5 152 ? 135.284 123.945 112.127 1.00 123.68 ?  152 TRP A CD2 1 
ATOM   7559 N NE1 . TRP E 5 152 ? 135.517 125.177 113.983 1.00 123.68 ?  152 TRP A NE1 1 
ATOM   7560 C CE2 . TRP E 5 152 ? 135.915 125.078 112.676 1.00 123.68 ?  152 TRP A CE2 1 
ATOM   7561 C CE3 . TRP E 5 152 ? 135.527 123.621 110.790 1.00 123.68 ?  152 TRP A CE3 1 
ATOM   7562 C CZ2 . TRP E 5 152 ? 136.772 125.887 111.937 1.00 123.68 ?  152 TRP A CZ2 1 
ATOM   7563 C CZ3 . TRP E 5 152 ? 136.378 124.426 110.058 1.00 123.68 ?  152 TRP A CZ3 1 
ATOM   7564 C CH2 . TRP E 5 152 ? 136.991 125.544 110.633 1.00 123.68 ?  152 TRP A CH2 1 
ATOM   7565 N N   . GLY E 5 153 ? 131.096 120.263 112.428 1.00 129.21 ?  153 GLY A N   1 
ATOM   7566 C CA  . GLY E 5 153 ? 130.554 118.964 112.066 1.00 129.21 ?  153 GLY A CA  1 
ATOM   7567 C C   . GLY E 5 153 ? 129.773 118.990 110.767 1.00 129.21 ?  153 GLY A C   1 
ATOM   7568 O O   . GLY E 5 153 ? 129.953 118.122 109.911 1.00 129.21 ?  153 GLY A O   1 
ATOM   7569 N N   . ILE E 5 154 ? 128.889 119.978 110.601 1.00 129.71 ?  154 ILE A N   1 
ATOM   7570 C CA  . ILE E 5 154 ? 128.179 120.098 109.322 1.00 129.71 ?  154 ILE A CA  1 
ATOM   7571 C C   . ILE E 5 154 ? 129.159 120.345 108.180 1.00 129.71 ?  154 ILE A C   1 
ATOM   7572 O O   . ILE E 5 154 ? 129.027 119.765 107.096 1.00 129.71 ?  154 ILE A O   1 
ATOM   7573 C CB  . ILE E 5 154 ? 127.072 121.174 109.354 1.00 129.71 ?  154 ILE A CB  1 
ATOM   7574 C CG1 . ILE E 5 154 ? 125.950 120.840 110.341 1.00 129.71 ?  154 ILE A CG1 1 
ATOM   7575 C CG2 . ILE E 5 154 ? 126.481 121.382 107.969 1.00 129.71 ?  154 ILE A CG2 1 
ATOM   7576 C CD1 . ILE E 5 154 ? 126.135 121.321 111.702 1.00 129.71 ?  154 ILE A CD1 1 
ATOM   7577 N N   . THR E 5 155 ? 130.154 121.208 108.397 1.00 131.64 ?  155 THR A N   1 
ATOM   7578 C CA  . THR E 5 155 ? 131.104 121.498 107.323 1.00 131.64 ?  155 THR A CA  1 
ATOM   7579 C C   . THR E 5 155 ? 131.854 120.241 106.889 1.00 131.64 ?  155 THR A C   1 
ATOM   7580 O O   . THR E 5 155 ? 131.969 119.953 105.690 1.00 131.64 ?  155 THR A O   1 
ATOM   7581 C CB  . THR E 5 155 ? 132.088 122.587 107.756 1.00 131.64 ?  155 THR A CB  1 
ATOM   7582 O OG1 . THR E 5 155 ? 132.835 122.138 108.893 1.00 131.64 ?  155 THR A OG1 1 
ATOM   7583 C CG2 . THR E 5 155 ? 131.353 123.874 108.092 1.00 131.64 ?  155 THR A CG2 1 
ATOM   7584 N N   . VAL E 5 156 ? 132.358 119.466 107.853 1.00 135.55 ?  156 VAL A N   1 
ATOM   7585 C CA  . VAL E 5 156 ? 133.108 118.266 107.497 1.00 135.55 ?  156 VAL A CA  1 
ATOM   7586 C C   . VAL E 5 156 ? 132.183 117.215 106.894 1.00 135.55 ?  156 VAL A C   1 
ATOM   7587 O O   . VAL E 5 156 ? 132.554 116.527 105.938 1.00 135.55 ?  156 VAL A O   1 
ATOM   7588 C CB  . VAL E 5 156 ? 133.895 117.722 108.706 1.00 135.55 ?  156 VAL A CB  1 
ATOM   7589 C CG1 . VAL E 5 156 ? 134.915 118.748 109.179 1.00 135.55 ?  156 VAL A CG1 1 
ATOM   7590 C CG2 . VAL E 5 156 ? 132.972 117.315 109.840 1.00 135.55 ?  156 VAL A CG2 1 
ATOM   7591 N N   . GLY E 5 157 ? 130.961 117.081 107.415 1.00 137.30 ?  157 GLY A N   1 
ATOM   7592 C CA  . GLY E 5 157 ? 130.025 116.143 106.823 1.00 137.30 ?  157 GLY A CA  1 
ATOM   7593 C C   . GLY E 5 157 ? 129.677 116.494 105.393 1.00 137.30 ?  157 GLY A C   1 
ATOM   7594 O O   . GLY E 5 157 ? 129.421 115.607 104.574 1.00 137.30 ?  157 GLY A O   1 
ATOM   7595 N N   . LEU E 5 158 ? 129.660 117.788 105.072 1.00 138.75 ?  158 LEU A N   1 
ATOM   7596 C CA  . LEU E 5 158 ? 129.417 118.206 103.698 1.00 138.75 ?  158 LEU A CA  1 
ATOM   7597 C C   . LEU E 5 158 ? 130.632 117.964 102.810 1.00 138.75 ?  158 LEU A C   1 
ATOM   7598 O O   . LEU E 5 158 ? 130.476 117.598 101.640 1.00 138.75 ?  158 LEU A O   1 
ATOM   7599 C CB  . LEU E 5 158 ? 129.031 119.685 103.659 1.00 138.75 ?  158 LEU A CB  1 
ATOM   7600 C CG  . LEU E 5 158 ? 127.650 120.092 104.179 1.00 138.75 ?  158 LEU A CG  1 
ATOM   7601 C CD1 . LEU E 5 158 ? 127.663 121.552 104.596 1.00 138.75 ?  158 LEU A CD1 1 
ATOM   7602 C CD2 . LEU E 5 158 ? 126.569 119.844 103.148 1.00 138.75 ?  158 LEU A CD2 1 
ATOM   7603 N N   . THR E 5 159 ? 131.841 118.164 103.337 1.00 141.48 ?  159 THR A N   1 
ATOM   7604 C CA  . THR E 5 159 ? 133.029 118.244 102.496 1.00 141.48 ?  159 THR A CA  1 
ATOM   7605 C C   . THR E 5 159 ? 133.923 117.005 102.511 1.00 141.48 ?  159 THR A C   1 
ATOM   7606 O O   . THR E 5 159 ? 134.912 116.978 101.771 1.00 141.48 ?  159 THR A O   1 
ATOM   7607 C CB  . THR E 5 159 ? 133.859 119.470 102.891 1.00 141.48 ?  159 THR A CB  1 
ATOM   7608 O OG1 . THR E 5 159 ? 134.096 119.451 104.304 1.00 141.48 ?  159 THR A OG1 1 
ATOM   7609 C CG2 . THR E 5 159 ? 133.122 120.747 102.521 1.00 141.48 ?  159 THR A CG2 1 
ATOM   7610 N N   . VAL E 5 160 ? 133.621 115.981 103.315 1.00 145.38 ?  160 VAL A N   1 
ATOM   7611 C CA  . VAL E 5 160 ? 134.480 114.797 103.309 1.00 145.38 ?  160 VAL A CA  1 
ATOM   7612 C C   . VAL E 5 160 ? 134.254 113.920 102.087 1.00 145.38 ?  160 VAL A C   1 
ATOM   7613 O O   . VAL E 5 160 ? 135.061 113.022 101.821 1.00 145.38 ?  160 VAL A O   1 
ATOM   7614 C CB  . VAL E 5 160 ? 134.303 113.943 104.580 1.00 145.38 ?  160 VAL A CB  1 
ATOM   7615 C CG1 . VAL E 5 160 ? 134.919 114.634 105.788 1.00 145.38 ?  160 VAL A CG1 1 
ATOM   7616 C CG2 . VAL E 5 160 ? 132.833 113.619 104.809 1.00 145.38 ?  160 VAL A CG2 1 
ATOM   7617 N N   . HIS E 5 161 ? 133.155 114.157 101.383 1.00 150.49 ?  161 HIS A N   1 
ATOM   7618 C CA  . HIS E 5 161 ? 132.858 113.376 100.195 1.00 150.49 ?  161 HIS A CA  1 
ATOM   7619 C C   . HIS E 5 161 ? 133.981 113.533 99.198  1.00 150.49 ?  161 HIS A C   1 
ATOM   7620 O O   . HIS E 5 161 ? 134.303 112.604 98.466  1.00 150.49 ?  161 HIS A O   1 
ATOM   7621 C CB  . HIS E 5 161 ? 131.533 113.808 99.572  1.00 150.49 ?  161 HIS A CB  1 
ATOM   7622 C CG  . HIS E 5 161 ? 131.553 115.188 98.996  1.00 150.49 ?  161 HIS A CG  1 
ATOM   7623 N ND1 . HIS E 5 161 ? 131.931 116.294 99.726  1.00 150.49 ?  161 HIS A ND1 1 
ATOM   7624 C CD2 . HIS E 5 161 ? 131.236 115.642 97.761  1.00 150.49 ?  161 HIS A CD2 1 
ATOM   7625 C CE1 . HIS E 5 161 ? 131.848 117.369 98.965  1.00 150.49 ?  161 HIS A CE1 1 
ATOM   7626 N NE2 . HIS E 5 161 ? 131.428 117.002 97.768  1.00 150.49 ?  161 HIS A NE2 1 
ATOM   7627 N N   . LEU E 5 162 ? 134.587 114.710 99.172  1.00 152.73 ?  162 LEU A N   1 
ATOM   7628 C CA  . LEU E 5 162 ? 135.695 114.934 98.271  1.00 152.73 ?  162 LEU A CA  1 
ATOM   7629 C C   . LEU E 5 162 ? 136.724 113.869 98.542  1.00 152.73 ?  162 LEU A C   1 
ATOM   7630 O O   . LEU E 5 162 ? 137.187 113.193 97.626  1.00 152.73 ?  162 LEU A O   1 
ATOM   7631 C CB  . LEU E 5 162 ? 136.297 116.314 98.486  1.00 152.73 ?  162 LEU A CB  1 
ATOM   7632 C CG  . LEU E 5 162 ? 135.630 117.470 97.705  1.00 152.73 ?  162 LEU A CG  1 
ATOM   7633 C CD1 . LEU E 5 162 ? 134.592 117.004 96.684  1.00 152.73 ?  162 LEU A CD1 1 
ATOM   7634 C CD2 . LEU E 5 162 ? 134.933 118.417 98.674  1.00 152.73 ?  162 LEU A CD2 1 
ATOM   7635 N N   . LEU E 5 163 ? 137.075 113.704 99.810  1.00 155.52 ?  163 LEU A N   1 
ATOM   7636 C CA  . LEU E 5 163 ? 138.079 112.720 100.171 1.00 155.52 ?  163 LEU A CA  1 
ATOM   7637 C C   . LEU E 5 163 ? 137.685 111.369 99.620  1.00 155.52 ?  163 LEU A C   1 
ATOM   7638 O O   . LEU E 5 163 ? 138.495 110.687 98.992  1.00 155.52 ?  163 LEU A O   1 
ATOM   7639 C CB  . LEU E 5 163 ? 138.242 112.667 101.685 1.00 155.52 ?  163 LEU A CB  1 
ATOM   7640 C CG  . LEU E 5 163 ? 139.030 113.854 102.234 1.00 155.52 ?  163 LEU A CG  1 
ATOM   7641 C CD1 . LEU E 5 163 ? 139.173 113.766 103.744 1.00 155.52 ?  163 LEU A CD1 1 
ATOM   7642 C CD2 . LEU E 5 163 ? 140.390 113.954 101.559 1.00 155.52 ?  163 LEU A CD2 1 
ATOM   7643 N N   . LYS E 5 164 ? 136.434 110.989 99.835  1.00 158.23 ?  164 LYS A N   1 
ATOM   7644 C CA  . LYS E 5 164 ? 135.953 109.703 99.349  1.00 158.23 ?  164 LYS A CA  1 
ATOM   7645 C C   . LYS E 5 164 ? 136.412 109.438 97.922  1.00 158.23 ?  164 LYS A C   1 
ATOM   7646 O O   . LYS E 5 164 ? 136.830 108.331 97.599  1.00 158.23 ?  164 LYS A O   1 
ATOM   7647 C CB  . LYS E 5 164 ? 134.427 109.645 99.437  1.00 158.23 ?  164 LYS A CB  1 
ATOM   7648 N N   . LYS E 5 165 ? 136.336 110.447 97.068  1.00 161.69 ?  165 LYS A N   1 
ATOM   7649 C CA  . LYS E 5 165 ? 136.733 110.270 95.680  1.00 161.69 ?  165 LYS A CA  1 
ATOM   7650 C C   . LYS E 5 165 ? 138.236 110.429 95.695  1.00 161.69 ?  165 LYS A C   1 
ATOM   7651 O O   . LYS E 5 165 ? 138.749 111.489 95.349  1.00 161.69 ?  165 LYS A O   1 
ATOM   7652 C CB  . LYS E 5 165 ? 136.081 111.326 94.793  1.00 161.69 ?  165 LYS A CB  1 
ATOM   7653 N N   . LYS E 5 166 ? 138.945 109.384 96.098  1.00 164.80 ?  166 LYS A N   1 
ATOM   7654 C CA  . LYS E 5 166 ? 140.397 109.429 96.091  1.00 164.80 ?  166 LYS A CA  1 
ATOM   7655 C C   . LYS E 5 166 ? 140.766 109.153 94.652  1.00 164.80 ?  166 LYS A C   1 
ATOM   7656 O O   . LYS E 5 166 ? 140.911 107.995 94.266  1.00 164.80 ?  166 LYS A O   1 
ATOM   7657 C CB  . LYS E 5 166 ? 140.982 108.355 96.997  1.00 164.80 ?  166 LYS A CB  1 
ATOM   7658 N N   . LEU E 5 167 ? 140.922 110.204 93.856  1.00 167.47 ?  167 LEU A N   1 
ATOM   7659 C CA  . LEU E 5 167 ? 141.220 110.031 92.440  1.00 167.47 ?  167 LEU A CA  1 
ATOM   7660 C C   . LEU E 5 167 ? 141.456 111.361 91.746  1.00 167.47 ?  167 LEU A C   1 
ATOM   7661 O O   . LEU E 5 167 ? 141.187 112.423 92.310  1.00 167.47 ?  167 LEU A O   1 
ATOM   7662 C CB  . LEU E 5 167 ? 140.071 109.311 91.742  1.00 167.47 ?  167 LEU A CB  1 
ATOM   7663 N N   . LEU E 5 168 ? 141.948 111.302 90.515  1.00 171.59 ?  168 LEU A N   1 
ATOM   7664 C CA  . LEU E 5 168 ? 142.187 112.526 89.767  1.00 171.59 ?  168 LEU A CA  1 
ATOM   7665 C C   . LEU E 5 168 ? 142.449 112.168 88.316  1.00 171.59 ?  168 LEU A C   1 
ATOM   7666 O O   . LEU E 5 168 ? 142.474 110.991 87.968  1.00 171.59 ?  168 LEU A O   1 
ATOM   7667 C CB  . LEU E 5 168 ? 143.563 113.101 90.106  1.00 171.59 ?  168 LEU A CB  1 
ATOM   7668 C CG  . LEU E 5 168 ? 144.750 112.145 90.126  1.00 171.59 ?  168 LEU A CG  1 
ATOM   7669 C CD1 . LEU E 5 168 ? 145.871 112.727 89.280  1.00 171.59 ?  168 LEU A CD1 1 
ATOM   7670 C CD2 . LEU E 5 168 ? 145.211 111.919 91.557  1.00 171.59 ?  168 LEU A CD2 1 
ATOM   7671 N N   . ILE E 5 169 ? 142.671 113.164 87.472  1.00 175.04 ?  169 ILE A N   1 
ATOM   7672 C CA  . ILE E 5 169 ? 142.820 112.935 86.042  1.00 175.04 ?  169 ILE A CA  1 
ATOM   7673 C C   . ILE E 5 169 ? 144.192 112.649 85.448  1.00 175.04 ?  169 ILE A C   1 
ATOM   7674 O O   . ILE E 5 169 ? 145.164 113.369 85.711  1.00 175.04 ?  169 ILE A O   1 
ATOM   7675 C CB  . ILE E 5 169 ? 142.248 114.259 85.516  1.00 175.04 ?  169 ILE A CB  1 
ATOM   7676 N N   . GLN E 5 170 ? 144.276 111.594 84.640  1.00 178.70 ?  170 GLN A N   1 
ATOM   7677 C CA  . GLN E 5 170 ? 145.535 111.153 84.057  1.00 178.70 ?  170 GLN A CA  1 
ATOM   7678 C C   . GLN E 5 170 ? 145.792 111.755 82.682  1.00 178.70 ?  170 GLN A C   1 
ATOM   7679 O O   . GLN E 5 170 ? 146.765 111.373 82.023  1.00 178.70 ?  170 GLN A O   1 
ATOM   7680 C CB  . GLN E 5 170 ? 145.569 109.625 83.976  1.00 178.70 ?  170 GLN A CB  1 
ATOM   7681 N N   . ASN E 5 171 ? 144.939 112.678 82.230  1.00 180.21 ?  171 ASN A N   1 
ATOM   7682 C CA  . ASN E 5 171 ? 145.151 113.311 80.932  1.00 180.21 ?  171 ASN A CA  1 
ATOM   7683 C C   . ASN E 5 171 ? 146.465 114.083 80.907  1.00 180.21 ?  171 ASN A C   1 
ATOM   7684 O O   . ASN E 5 171 ? 147.237 113.990 79.946  1.00 180.21 ?  171 ASN A O   1 
ATOM   7685 C CB  . ASN E 5 171 ? 143.975 114.232 80.603  1.00 180.21 ?  171 ASN A CB  1 
ATOM   7686 N N   . GLY E 5 172 ? 146.734 114.852 81.959  1.00 179.19 ?  172 GLY A N   1 
ATOM   7687 C CA  . GLY E 5 172 ? 147.986 115.574 82.067  1.00 179.19 ?  172 GLY A CA  1 
ATOM   7688 C C   . GLY E 5 172 ? 149.035 114.822 82.858  1.00 179.19 ?  172 GLY A C   1 
ATOM   7689 O O   . GLY E 5 172 ? 149.593 115.358 83.821  1.00 179.19 ?  172 GLY A O   1 
ATOM   7690 N N   . THR E 5 173 ? 149.313 113.581 82.452  1.00 178.95 ?  173 THR A N   1 
ATOM   7691 C CA  . THR E 5 173 ? 150.287 112.720 83.128  1.00 178.95 ?  173 THR A CA  1 
ATOM   7692 C C   . THR E 5 173 ? 149.978 112.592 84.618  1.00 178.95 ?  173 THR A C   1 
ATOM   7693 O O   . THR E 5 173 ? 150.870 112.658 85.467  1.00 178.95 ?  173 THR A O   1 
ATOM   7694 C CB  . THR E 5 173 ? 151.718 113.221 82.908  1.00 178.95 ?  173 THR A CB  1 
ATOM   7695 N N   . ALA E 5 174 ? 148.693 112.405 84.933  1.00 178.77 ?  174 ALA A N   1 
ATOM   7696 C CA  . ALA E 5 174 ? 148.221 112.245 86.311  1.00 178.77 ?  174 ALA A CA  1 
ATOM   7697 C C   . ALA E 5 174 ? 148.622 113.432 87.184  1.00 178.77 ?  174 ALA A C   1 
ATOM   7698 O O   . ALA E 5 174 ? 149.081 113.268 88.316  1.00 178.77 ?  174 ALA A O   1 
ATOM   7699 C CB  . ALA E 5 174 ? 148.716 110.930 86.918  1.00 178.77 ?  174 ALA A CB  1 
ATOM   7700 N N   . ASN E 5 175 ? 148.447 114.643 86.650  1.00 175.81 ?  175 ASN A N   1 
ATOM   7701 C CA  . ASN E 5 175 ? 148.775 115.863 87.378  1.00 175.81 ?  175 ASN A CA  1 
ATOM   7702 C C   . ASN E 5 175 ? 147.634 116.866 87.529  1.00 175.81 ?  175 ASN A C   1 
ATOM   7703 O O   . ASN E 5 175 ? 147.803 117.930 88.106  1.00 175.81 ?  175 ASN A O   1 
ATOM   7704 C CB  . ASN E 5 175 ? 150.092 116.463 86.883  1.00 175.81 ?  175 ASN A CB  1 
ATOM   7705 C CG  . ASN E 5 175 ? 151.213 115.443 86.820  1.00 175.81 ?  175 ASN A CG  1 
ATOM   7706 O OD1 . ASN E 5 175 ? 151.919 115.342 85.817  1.00 175.81 ?  175 ASN A OD1 1 
ATOM   7707 N ND2 . ASN E 5 175 ? 151.386 114.686 87.896  1.00 175.81 ?  175 ASN A ND2 1 
ATOM   7708 N N   . VAL E 5 176 ? 146.426 116.478 87.136  1.00 172.60 ?  176 VAL A N   1 
ATOM   7709 C CA  . VAL E 5 176 ? 145.279 117.379 86.974  1.00 172.60 ?  176 VAL A CA  1 
ATOM   7710 C C   . VAL E 5 176 ? 144.360 116.875 88.088  1.00 172.60 ?  176 VAL A C   1 
ATOM   7711 O O   . VAL E 5 176 ? 143.507 116.013 87.883  1.00 172.60 ?  176 VAL A O   1 
ATOM   7712 C CB  . VAL E 5 176 ? 144.687 117.214 85.566  1.00 172.60 ?  176 VAL A CB  1 
ATOM   7713 C CG1 . VAL E 5 176 ? 143.697 118.299 85.139  1.00 172.60 ?  176 VAL A CG1 1 
ATOM   7714 C CG2 . VAL E 5 176 ? 145.690 116.944 84.474  1.00 172.60 ?  176 VAL A CG2 1 
ATOM   7715 N N   . CYS E 5 177 ? 144.643 117.275 89.327  1.00 167.83 ?  177 CYS A N   1 
ATOM   7716 C CA  . CYS E 5 177 ? 143.855 116.842 90.479  1.00 167.83 ?  177 CYS A CA  1 
ATOM   7717 C C   . CYS E 5 177 ? 142.959 118.052 90.750  1.00 167.83 ?  177 CYS A C   1 
ATOM   7718 O O   . CYS E 5 177 ? 143.394 119.026 91.360  1.00 167.83 ?  177 CYS A O   1 
ATOM   7719 C CB  . CYS E 5 177 ? 144.696 116.411 91.682  1.00 167.83 ?  177 CYS A CB  1 
ATOM   7720 S SG  . CYS E 5 177 ? 143.705 115.883 93.106  1.00 167.83 ?  177 CYS A SG  1 
ATOM   7721 N N   . ILE E 5 178 ? 141.738 118.022 90.209  1.00 163.06 ?  178 ILE A N   1 
ATOM   7722 C CA  . ILE E 5 178 ? 140.744 119.095 90.312  1.00 163.06 ?  178 ILE A CA  1 
ATOM   7723 C C   . ILE E 5 178 ? 139.352 118.525 90.611  1.00 163.06 ?  178 ILE A C   1 
ATOM   7724 O O   . ILE E 5 178 ? 138.999 117.447 90.142  1.00 163.06 ?  178 ILE A O   1 
ATOM   7725 C CB  . ILE E 5 178 ? 140.735 120.006 89.058  1.00 163.06 ?  178 ILE A CB  1 
ATOM   7726 C CG1 . ILE E 5 178 ? 140.377 119.245 87.759  1.00 163.06 ?  178 ILE A CG1 1 
ATOM   7727 C CG2 . ILE E 5 178 ? 142.077 120.752 88.933  1.00 163.06 ?  178 ILE A CG2 1 
ATOM   7728 C CD1 . ILE E 5 178 ? 140.264 120.141 86.518  1.00 163.06 ?  178 ILE A CD1 1 
ATOM   7729 N N   . SER E 5 179 ? 138.544 119.256 91.380  1.00 156.81 ?  179 SER A N   1 
ATOM   7730 C CA  . SER E 5 179 ? 137.191 118.858 91.774  1.00 156.81 ?  179 SER A CA  1 
ATOM   7731 C C   . SER E 5 179 ? 136.099 119.489 90.910  1.00 156.81 ?  179 SER A C   1 
ATOM   7732 O O   . SER E 5 179 ? 135.081 118.852 90.666  1.00 156.81 ?  179 SER A O   1 
ATOM   7733 C CB  . SER E 5 179 ? 136.953 119.191 93.252  1.00 156.81 ?  179 SER A CB  1 
ATOM   7734 O OG  . SER E 5 179 ? 136.998 120.588 93.479  1.00 156.81 ?  179 SER A OG  1 
ATOM   7735 N N   . PHE E 5 180 ? 136.257 120.725 90.432  1.00 154.63 ?  180 PHE A N   1 
ATOM   7736 C CA  . PHE E 5 180 ? 135.157 121.524 89.866  1.00 154.63 ?  180 PHE A CA  1 
ATOM   7737 C C   . PHE E 5 180 ? 134.905 121.311 88.360  1.00 154.63 ?  180 PHE A C   1 
ATOM   7738 O O   . PHE E 5 180 ? 134.626 122.239 87.606  1.00 154.63 ?  180 PHE A O   1 
ATOM   7739 C CB  . PHE E 5 180 ? 135.346 122.988 90.263  1.00 154.63 ?  180 PHE A CB  1 
ATOM   7740 C CG  . PHE E 5 180 ? 134.976 123.286 91.701  1.00 154.63 ?  180 PHE A CG  1 
ATOM   7741 C CD1 . PHE E 5 180 ? 133.618 123.370 92.059  1.00 154.63 ?  180 PHE A CD1 1 
ATOM   7742 C CD2 . PHE E 5 180 ? 135.968 123.556 92.662  1.00 154.63 ?  180 PHE A CD2 1 
ATOM   7743 C CE1 . PHE E 5 180 ? 133.255 123.727 93.366  1.00 154.63 ?  180 PHE A CE1 1 
ATOM   7744 C CE2 . PHE E 5 180 ? 135.602 123.908 93.974  1.00 154.63 ?  180 PHE A CE2 1 
ATOM   7745 C CZ  . PHE E 5 180 ? 134.244 124.000 94.324  1.00 154.63 ?  180 PHE A CZ  1 
ATOM   7746 N N   . SER E 5 181 ? 134.950 120.054 87.932  1.00 164.84 ?  181 SER A N   1 
ATOM   7747 C CA  . SER E 5 181 ? 134.763 119.731 86.509  1.00 164.84 ?  181 SER A CA  1 
ATOM   7748 C C   . SER E 5 181 ? 133.505 120.281 85.859  1.00 164.84 ?  181 SER A C   1 
ATOM   7749 O O   . SER E 5 181 ? 132.545 120.623 86.538  1.00 164.84 ?  181 SER A O   1 
ATOM   7750 C CB  . SER E 5 181 ? 134.706 118.217 86.342  1.00 164.84 ?  181 SER A CB  1 
ATOM   7751 O OG  . SER E 5 181 ? 133.366 117.758 86.348  1.00 164.84 ?  181 SER A OG  1 
ATOM   7752 N N   . ILE E 5 182 ? 133.494 120.329 84.533  1.00 173.24 ?  182 ILE A N   1 
ATOM   7753 C CA  . ILE E 5 182 ? 132.338 120.859 83.819  1.00 173.24 ?  182 ILE A CA  1 
ATOM   7754 C C   . ILE E 5 182 ? 131.718 119.824 82.886  1.00 173.24 ?  182 ILE A C   1 
ATOM   7755 O O   . ILE E 5 182 ? 131.743 119.972 81.664  1.00 173.24 ?  182 ILE A O   1 
ATOM   7756 C CB  . ILE E 5 182 ? 132.756 122.149 83.063  1.00 173.24 ?  182 ILE A CB  1 
ATOM   7757 C CG1 . ILE E 5 182 ? 131.593 122.730 82.238  1.00 173.24 ?  182 ILE A CG1 1 
ATOM   7758 C CG2 . ILE E 5 182 ? 133.986 121.898 82.198  1.00 173.24 ?  182 ILE A CG2 1 
ATOM   7759 C CD1 . ILE E 5 182 ? 130.250 122.709 82.936  1.00 173.24 ?  182 ILE A CD1 1 
ATOM   7760 N N   . CYS E 5 183 ? 131.144 118.771 83.441  1.00 180.09 ?  183 CYS A N   1 
ATOM   7761 C CA  . CYS E 5 183 ? 130.656 117.715 82.565  1.00 180.09 ?  183 CYS A CA  1 
ATOM   7762 C C   . CYS E 5 183 ? 129.352 117.109 83.037  1.00 180.09 ?  183 CYS A C   1 
ATOM   7763 O O   . CYS E 5 183 ? 129.354 116.149 83.809  1.00 180.09 ?  183 CYS A O   1 
ATOM   7764 C CB  . CYS E 5 183 ? 131.732 116.653 82.444  1.00 180.09 ?  183 CYS A CB  1 
ATOM   7765 S SG  . CYS E 5 183 ? 133.168 117.088 83.442  1.00 180.09 ?  183 CYS A SG  1 
ATOM   7766 N N   . HIS E 5 184 ? 128.241 117.664 82.566  1.00 177.66 ?  184 HIS A N   1 
ATOM   7767 C CA  . HIS E 5 184 ? 126.930 117.174 82.970  1.00 177.66 ?  184 HIS A CA  1 
ATOM   7768 C C   . HIS E 5 184 ? 126.667 117.152 84.460  1.00 177.66 ?  184 HIS A C   1 
ATOM   7769 O O   . HIS E 5 184 ? 126.991 118.109 85.165  1.00 177.66 ?  184 HIS A O   1 
ATOM   7770 C CB  . HIS E 5 184 ? 126.611 115.845 82.284  1.00 177.66 ?  184 HIS A CB  1 
ATOM   7771 N N   . THR E 5 185 ? 126.053 116.080 84.940  1.00 172.69 ?  185 THR A N   1 
ATOM   7772 C CA  . THR E 5 185 ? 125.802 115.930 86.377  1.00 172.69 ?  185 THR A CA  1 
ATOM   7773 C C   . THR E 5 185 ? 125.483 117.160 87.223  1.00 172.69 ?  185 THR A C   1 
ATOM   7774 O O   . THR E 5 185 ? 125.500 118.289 86.736  1.00 172.69 ?  185 THR A O   1 
ATOM   7775 C CB  . THR E 5 185 ? 127.069 115.225 86.918  1.00 172.69 ?  185 THR A CB  1 
ATOM   7776 O OG1 . THR E 5 185 ? 127.797 114.628 85.836  1.00 172.69 ?  185 THR A OG1 1 
ATOM   7777 C CG2 . THR E 5 185 ? 126.695 114.147 87.924  1.00 172.69 ?  185 THR A CG2 1 
ATOM   7778 N N   . PHE E 5 186 ? 124.890 117.104 88.295  1.00 165.11 ?  186 PHE A N   1 
ATOM   7779 C CA  . PHE E 5 186 ? 124.938 117.933 89.489  1.00 165.11 ?  186 PHE A CA  1 
ATOM   7780 C C   . PHE E 5 186 ? 124.961 117.210 90.804  1.00 165.11 ?  186 PHE A C   1 
ATOM   7781 O O   . PHE E 5 186 ? 123.926 117.044 91.446  1.00 165.11 ?  186 PHE A O   1 
ATOM   7782 C CB  . PHE E 5 186 ? 123.596 118.604 89.252  1.00 165.11 ?  186 PHE A CB  1 
ATOM   7783 N N   . ARG E 5 187 ? 126.139 116.766 91.215  1.00 157.84 ?  187 ARG A N   1 
ATOM   7784 C CA  . ARG E 5 187 ? 126.254 115.964 92.419  1.00 157.84 ?  187 ARG A CA  1 
ATOM   7785 C C   . ARG E 5 187 ? 126.323 116.863 93.654  1.00 157.84 ?  187 ARG A C   1 
ATOM   7786 O O   . ARG E 5 187 ? 126.171 118.085 93.574  1.00 157.84 ?  187 ARG A O   1 
ATOM   7787 C CB  . ARG E 5 187 ? 127.472 115.038 92.330  1.00 157.84 ?  187 ARG A CB  1 
ATOM   7788 N N   . TRP E 5 188 ? 126.549 116.227 94.805  1.00 152.52 ?  188 TRP A N   1 
ATOM   7789 C CA  . TRP E 5 188 ? 126.666 116.920 96.086  1.00 152.52 ?  188 TRP A CA  1 
ATOM   7790 C C   . TRP E 5 188 ? 127.742 118.004 96.030  1.00 152.52 ?  188 TRP A C   1 
ATOM   7791 O O   . TRP E 5 188 ? 127.548 119.131 96.519  1.00 152.52 ?  188 TRP A O   1 
ATOM   7792 C CB  . TRP E 5 188 ? 126.961 115.853 97.146  1.00 152.52 ?  188 TRP A CB  1 
ATOM   7793 C CG  . TRP E 5 188 ? 126.971 116.237 98.582  1.00 152.52 ?  188 TRP A CG  1 
ATOM   7794 C CD1 . TRP E 5 188 ? 128.063 116.490 99.347  1.00 152.52 ?  188 TRP A CD1 1 
ATOM   7795 C CD2 . TRP E 5 188 ? 125.841 116.328 99.457  1.00 152.52 ?  188 TRP A CD2 1 
ATOM   7796 N NE1 . TRP E 5 188 ? 127.691 116.771 100.636 1.00 152.52 ?  188 TRP A NE1 1 
ATOM   7797 C CE2 . TRP E 5 188 ? 126.330 116.678 100.731 1.00 152.52 ?  188 TRP A CE2 1 
ATOM   7798 C CE3 . TRP E 5 188 ? 124.464 116.164 99.285  1.00 152.52 ?  188 TRP A CE3 1 
ATOM   7799 C CZ2 . TRP E 5 188 ? 125.492 116.867 101.826 1.00 152.52 ?  188 TRP A CZ2 1 
ATOM   7800 C CZ3 . TRP E 5 188 ? 123.635 116.353 100.371 1.00 152.52 ?  188 TRP A CZ3 1 
ATOM   7801 C CH2 . TRP E 5 188 ? 124.150 116.702 101.626 1.00 152.52 ?  188 TRP A CH2 1 
ATOM   7802 N N   . HIS E 5 189 ? 128.880 117.679 95.422  1.00 154.43 ?  189 HIS A N   1 
ATOM   7803 C CA  . HIS E 5 189 ? 129.877 118.685 95.091  1.00 154.43 ?  189 HIS A CA  1 
ATOM   7804 C C   . HIS E 5 189 ? 129.322 119.653 94.057  1.00 154.43 ?  189 HIS A C   1 
ATOM   7805 O O   . HIS E 5 189 ? 128.629 119.255 93.116  1.00 154.43 ?  189 HIS A O   1 
ATOM   7806 C CB  . HIS E 5 189 ? 131.152 118.033 94.555  1.00 154.43 ?  189 HIS A CB  1 
ATOM   7807 C CG  . HIS E 5 189 ? 132.273 119.052 94.656  1.00 154.43 ?  189 HIS A CG  1 
ATOM   7808 N ND1 . HIS E 5 189 ? 132.570 119.754 95.826  1.00 154.43 ?  189 HIS A ND1 1 
ATOM   7809 C CD2 . HIS E 5 189 ? 132.989 119.612 93.635  1.00 154.43 ?  189 HIS A CD2 1 
ATOM   7810 C CE1 . HIS E 5 189 ? 133.491 120.673 95.496  1.00 154.43 ?  189 HIS A CE1 1 
ATOM   7811 N NE2 . HIS E 5 189 ? 133.764 120.609 94.184  1.00 154.43 ?  189 HIS A NE2 1 
ATOM   7812 N N   . GLU E 5 190 ? 129.619 120.937 94.264  1.00 150.94 ?  190 GLU A N   1 
ATOM   7813 C CA  . GLU E 5 190 ? 129.113 122.077 93.503  1.00 150.94 ?  190 GLU A CA  1 
ATOM   7814 C C   . GLU E 5 190 ? 127.646 122.318 93.836  1.00 150.94 ?  190 GLU A C   1 
ATOM   7815 O O   . GLU E 5 190 ? 127.138 123.432 93.668  1.00 150.94 ?  190 GLU A O   1 
ATOM   7816 C CB  . GLU E 5 190 ? 129.309 121.871 91.995  1.00 150.94 ?  190 GLU A CB  1 
ATOM   7817 C CG  . GLU E 5 190 ? 128.761 122.993 91.134  1.00 150.94 ?  190 GLU A CG  1 
ATOM   7818 C CD  . GLU E 5 190 ? 129.301 124.352 91.536  1.00 150.94 ?  190 GLU A CD  1 
ATOM   7819 O OE1 . GLU E 5 190 ? 130.529 124.472 91.729  1.00 150.94 ?  190 GLU A OE1 1 
ATOM   7820 O OE2 . GLU E 5 190 ? 128.498 125.301 91.658  1.00 150.94 -1 190 GLU A OE2 1 
ATOM   7821 N N   . ALA E 5 191 ? 126.998 121.333 94.457  1.00 147.54 ?  191 ALA A N   1 
ATOM   7822 C CA  . ALA E 5 191 ? 125.703 121.602 95.063  1.00 147.54 ?  191 ALA A CA  1 
ATOM   7823 C C   . ALA E 5 191 ? 125.886 122.435 96.319  1.00 147.54 ?  191 ALA A C   1 
ATOM   7824 O O   . ALA E 5 191 ? 125.179 123.431 96.522  1.00 147.54 ?  191 ALA A O   1 
ATOM   7825 C CB  . ALA E 5 191 ? 124.965 120.301 95.372  1.00 147.54 ?  191 ALA A CB  1 
ATOM   7826 N N   . MET E 5 192 ? 126.875 122.081 97.153  1.00 143.72 ?  192 MET A N   1 
ATOM   7827 C CA  . MET E 5 192 ? 127.205 123.013 98.232  1.00 143.72 ?  192 MET A CA  1 
ATOM   7828 C C   . MET E 5 192 ? 127.728 124.338 97.690  1.00 143.72 ?  192 MET A C   1 
ATOM   7829 O O   . MET E 5 192 ? 127.502 125.383 98.306  1.00 143.72 ?  192 MET A O   1 
ATOM   7830 C CB  . MET E 5 192 ? 128.251 122.461 99.202  1.00 143.72 ?  192 MET A CB  1 
ATOM   7831 C CG  . MET E 5 192 ? 127.803 121.436 100.219 1.00 143.72 ?  192 MET A CG  1 
ATOM   7832 S SD  . MET E 5 192 ? 127.530 119.871 99.429  1.00 143.72 ?  192 MET A SD  1 
ATOM   7833 C CE  . MET E 5 192 ? 129.260 119.480 99.191  1.00 143.72 ?  192 MET A CE  1 
ATOM   7834 N N   . PHE E 5 193 ? 128.436 124.323 96.557  1.00 140.15 ?  193 PHE A N   1 
ATOM   7835 C CA  . PHE E 5 193 ? 129.008 125.564 96.038  1.00 140.15 ?  193 PHE A CA  1 
ATOM   7836 C C   . PHE E 5 193 ? 127.917 126.539 95.604  1.00 140.15 ?  193 PHE A C   1 
ATOM   7837 O O   . PHE E 5 193 ? 128.025 127.746 95.848  1.00 140.15 ?  193 PHE A O   1 
ATOM   7838 C CB  . PHE E 5 193 ? 129.964 125.263 94.884  1.00 140.15 ?  193 PHE A CB  1 
ATOM   7839 C CG  . PHE E 5 193 ? 130.787 126.443 94.446  1.00 140.15 ?  193 PHE A CG  1 
ATOM   7840 C CD1 . PHE E 5 193 ? 131.906 126.818 95.210  1.00 140.15 ?  193 PHE A CD1 1 
ATOM   7841 C CD2 . PHE E 5 193 ? 130.440 127.175 93.324  1.00 140.15 ?  193 PHE A CD2 1 
ATOM   7842 C CE1 . PHE E 5 193 ? 132.690 127.905 94.800  1.00 140.15 ?  193 PHE A CE1 1 
ATOM   7843 C CE2 . PHE E 5 193 ? 131.203 128.254 92.922  1.00 140.15 ?  193 PHE A CE2 1 
ATOM   7844 C CZ  . PHE E 5 193 ? 132.326 128.609 93.642  1.00 140.15 ?  193 PHE A CZ  1 
ATOM   7845 N N   . LEU E 5 194 ? 126.861 126.035 94.956  1.00 139.78 ?  194 LEU A N   1 
ATOM   7846 C CA  . LEU E 5 194 ? 125.724 126.891 94.625  1.00 139.78 ?  194 LEU A CA  1 
ATOM   7847 C C   . LEU E 5 194 ? 124.914 127.254 95.865  1.00 139.78 ?  194 LEU A C   1 
ATOM   7848 O O   . LEU E 5 194 ? 124.394 128.372 95.964  1.00 139.78 ?  194 LEU A O   1 
ATOM   7849 C CB  . LEU E 5 194 ? 124.827 126.216 93.588  1.00 139.78 ?  194 LEU A CB  1 
ATOM   7850 C CG  . LEU E 5 194 ? 125.430 125.999 92.201  1.00 139.78 ?  194 LEU A CG  1 
ATOM   7851 C CD1 . LEU E 5 194 ? 124.482 125.199 91.325  1.00 139.78 ?  194 LEU A CD1 1 
ATOM   7852 C CD2 . LEU E 5 194 ? 125.783 127.326 91.538  1.00 139.78 ?  194 LEU A CD2 1 
ATOM   7853 N N   . LEU E 5 195 ? 124.783 126.325 96.818  1.00 132.36 ?  195 LEU A N   1 
ATOM   7854 C CA  . LEU E 5 195 ? 123.960 126.591 97.993  1.00 132.36 ?  195 LEU A CA  1 
ATOM   7855 C C   . LEU E 5 195 ? 124.581 127.662 98.882  1.00 132.36 ?  195 LEU A C   1 
ATOM   7856 O O   . LEU E 5 195 ? 123.867 128.499 99.445  1.00 132.36 ?  195 LEU A O   1 
ATOM   7857 C CB  . LEU E 5 195 ? 123.748 125.293 98.775  1.00 132.36 ?  195 LEU A CB  1 
ATOM   7858 C CG  . LEU E 5 195 ? 122.754 125.250 99.940  1.00 132.36 ?  195 LEU A CG  1 
ATOM   7859 C CD1 . LEU E 5 195 ? 122.196 123.842 100.071 1.00 132.36 ?  195 LEU A CD1 1 
ATOM   7860 C CD2 . LEU E 5 195 ? 123.388 125.692 101.252 1.00 132.36 ?  195 LEU A CD2 1 
ATOM   7861 N N   . GLU E 5 196 ? 125.906 127.650 99.025  1.00 129.42 ?  196 GLU A N   1 
ATOM   7862 C CA  . GLU E 5 196 ? 126.578 128.526 99.975  1.00 129.42 ?  196 GLU A CA  1 
ATOM   7863 C C   . GLU E 5 196 ? 126.522 129.996 99.583  1.00 129.42 ?  196 GLU A C   1 
ATOM   7864 O O   . GLU E 5 196 ? 126.825 130.849 100.423 1.00 129.42 ?  196 GLU A O   1 
ATOM   7865 C CB  . GLU E 5 196 ? 128.032 128.088 100.140 1.00 129.42 ?  196 GLU A CB  1 
ATOM   7866 C CG  . GLU E 5 196 ? 128.891 128.341 98.919  1.00 129.42 ?  196 GLU A CG  1 
ATOM   7867 C CD  . GLU E 5 196 ? 130.248 127.682 99.025  1.00 129.42 ?  196 GLU A CD  1 
ATOM   7868 O OE1 . GLU E 5 196 ? 130.491 126.985 100.032 1.00 129.42 ?  196 GLU A OE1 1 
ATOM   7869 O OE2 . GLU E 5 196 ? 131.070 127.861 98.104  1.00 129.42 -1 196 GLU A OE2 1 
ATOM   7870 N N   . PHE E 5 197 ? 126.157 130.316 98.345  1.00 125.53 ?  197 PHE A N   1 
ATOM   7871 C CA  . PHE E 5 197 ? 126.006 131.702 97.929  1.00 125.53 ?  197 PHE A CA  1 
ATOM   7872 C C   . PHE E 5 197 ? 124.545 132.112 97.792  1.00 125.53 ?  197 PHE A C   1 
ATOM   7873 O O   . PHE E 5 197 ? 124.263 133.234 97.362  1.00 125.53 ?  197 PHE A O   1 
ATOM   7874 C CB  . PHE E 5 197 ? 126.750 131.942 96.610  1.00 125.53 ?  197 PHE A CB  1 
ATOM   7875 C CG  . PHE E 5 197 ? 126.794 133.383 96.194  1.00 125.53 ?  197 PHE A CG  1 
ATOM   7876 C CD1 . PHE E 5 197 ? 127.316 134.340 97.044  1.00 125.53 ?  197 PHE A CD1 1 
ATOM   7877 C CD2 . PHE E 5 197 ? 126.299 133.784 94.965  1.00 125.53 ?  197 PHE A CD2 1 
ATOM   7878 C CE1 . PHE E 5 197 ? 127.359 135.667 96.675  1.00 125.53 ?  197 PHE A CE1 1 
ATOM   7879 C CE2 . PHE E 5 197 ? 126.337 135.112 94.591  1.00 125.53 ?  197 PHE A CE2 1 
ATOM   7880 C CZ  . PHE E 5 197 ? 126.867 136.054 95.450  1.00 125.53 ?  197 PHE A CZ  1 
ATOM   7881 N N   . PHE E 5 198 ? 123.608 131.236 98.148  1.00 121.79 ?  198 PHE A N   1 
ATOM   7882 C CA  . PHE E 5 198 ? 122.189 131.559 98.105  1.00 121.79 ?  198 PHE A CA  1 
ATOM   7883 C C   . PHE E 5 198 ? 121.579 131.606 99.500  1.00 121.79 ?  198 PHE A C   1 
ATOM   7884 O O   . PHE E 5 198 ? 120.990 132.620 99.885  1.00 121.79 ?  198 PHE A O   1 
ATOM   7885 C CB  . PHE E 5 198 ? 121.445 130.546 97.222  1.00 121.79 ?  198 PHE A CB  1 
ATOM   7886 C CG  . PHE E 5 198 ? 121.580 130.811 95.748  1.00 121.79 ?  198 PHE A CG  1 
ATOM   7887 C CD1 . PHE E 5 198 ? 122.367 131.853 95.285  1.00 121.79 ?  198 PHE A CD1 1 
ATOM   7888 C CD2 . PHE E 5 198 ? 120.913 130.023 94.825  1.00 121.79 ?  198 PHE A CD2 1 
ATOM   7889 C CE1 . PHE E 5 198 ? 122.494 132.100 93.932  1.00 121.79 ?  198 PHE A CE1 1 
ATOM   7890 C CE2 . PHE E 5 198 ? 121.036 130.265 93.469  1.00 121.79 ?  198 PHE A CE2 1 
ATOM   7891 C CZ  . PHE E 5 198 ? 121.827 131.305 93.023  1.00 121.79 ?  198 PHE A CZ  1 
ATOM   7892 N N   . LEU E 5 199 ? 121.713 130.528 100.279 1.00 113.96 ?  199 LEU A N   1 
ATOM   7893 C CA  . LEU E 5 199 ? 121.170 130.545 101.636 1.00 113.96 ?  199 LEU A CA  1 
ATOM   7894 C C   . LEU E 5 199 ? 122.006 131.416 102.568 1.00 113.96 ?  199 LEU A C   1 
ATOM   7895 O O   . LEU E 5 199 ? 121.434 132.308 103.220 1.00 113.96 ?  199 LEU A O   1 
ATOM   7896 C CB  . LEU E 5 199 ? 121.010 129.108 102.149 1.00 113.96 ?  199 LEU A CB  1 
ATOM   7897 C CG  . LEU E 5 199 ? 120.303 128.829 103.478 1.00 113.96 ?  199 LEU A CG  1 
ATOM   7898 C CD1 . LEU E 5 199 ? 119.697 127.438 103.454 1.00 113.96 ?  199 LEU A CD1 1 
ATOM   7899 C CD2 . LEU E 5 199 ? 121.261 128.949 104.652 1.00 113.96 ?  199 LEU A CD2 1 
ATOM   7900 N N   . PRO E 5 200 ? 123.328 131.223 102.702 1.00 111.83 ?  200 PRO A N   1 
ATOM   7901 C CA  . PRO E 5 200 ? 124.097 132.146 103.553 1.00 111.83 ?  200 PRO A CA  1 
ATOM   7902 C C   . PRO E 5 200 ? 124.040 133.588 103.084 1.00 111.83 ?  200 PRO A C   1 
ATOM   7903 O O   . PRO E 5 200 ? 123.963 134.497 103.918 1.00 111.83 ?  200 PRO A O   1 
ATOM   7904 C CB  . PRO E 5 200 ? 125.522 131.579 103.480 1.00 111.83 ?  200 PRO A CB  1 
ATOM   7905 C CG  . PRO E 5 200 ? 125.333 130.146 103.152 1.00 111.83 ?  200 PRO A CG  1 
ATOM   7906 C CD  . PRO E 5 200 ? 124.183 130.135 102.196 1.00 111.83 ?  200 PRO A CD  1 
ATOM   7907 N N   . LEU E 5 201 ? 124.067 133.827 101.770 1.00 109.99 ?  201 LEU A N   1 
ATOM   7908 C CA  . LEU E 5 201 ? 123.972 135.198 101.277 1.00 109.99 ?  201 LEU A CA  1 
ATOM   7909 C C   . LEU E 5 201 ? 122.626 135.811 101.628 1.00 109.99 ?  201 LEU A C   1 
ATOM   7910 O O   . LEU E 5 201 ? 122.555 136.971 102.050 1.00 109.99 ?  201 LEU A O   1 
ATOM   7911 C CB  . LEU E 5 201 ? 124.194 135.240 99.767  1.00 109.99 ?  201 LEU A CB  1 
ATOM   7912 C CG  . LEU E 5 201 ? 123.816 136.565 99.099  1.00 109.99 ?  201 LEU A CG  1 
ATOM   7913 C CD1 . LEU E 5 201 ? 124.830 137.646 99.436  1.00 109.99 ?  201 LEU A CD1 1 
ATOM   7914 C CD2 . LEU E 5 201 ? 123.675 136.407 97.594  1.00 109.99 ?  201 LEU A CD2 1 
ATOM   7915 N N   . GLY E 5 202 ? 121.546 135.047 101.461 1.00 105.62 ?  202 GLY A N   1 
ATOM   7916 C CA  . GLY E 5 202 ? 120.236 135.548 101.836 1.00 105.62 ?  202 GLY A CA  1 
ATOM   7917 C C   . GLY E 5 202 ? 120.136 135.858 103.316 1.00 105.62 ?  202 GLY A C   1 
ATOM   7918 O O   . GLY E 5 202 ? 119.585 136.890 103.707 1.00 105.62 ?  202 GLY A O   1 
ATOM   7919 N N   . ILE E 5 203 ? 120.678 134.975 104.159 1.00 99.71  ?  203 ILE A N   1 
ATOM   7920 C CA  . ILE E 5 203 ? 120.629 135.207 105.600 1.00 99.71  ?  203 ILE A CA  1 
ATOM   7921 C C   . ILE E 5 203 ? 121.429 136.449 105.972 1.00 99.71  ?  203 ILE A C   1 
ATOM   7922 O O   . ILE E 5 203 ? 120.974 137.280 106.767 1.00 99.71  ?  203 ILE A O   1 
ATOM   7923 C CB  . ILE E 5 203 ? 121.125 133.966 106.364 1.00 99.71  ?  203 ILE A CB  1 
ATOM   7924 C CG1 . ILE E 5 203 ? 120.115 132.826 106.238 1.00 99.71  ?  203 ILE A CG1 1 
ATOM   7925 C CG2 . ILE E 5 203 ? 121.351 134.300 107.825 1.00 99.71  ?  203 ILE A CG2 1 
ATOM   7926 C CD1 . ILE E 5 203 ? 120.487 131.597 107.035 1.00 99.71  ?  203 ILE A CD1 1 
ATOM   7927 N N   . ILE E 5 204 ? 122.630 136.598 105.406 1.00 100.26 ?  204 ILE A N   1 
ATOM   7928 C CA  . ILE E 5 204 ? 123.455 137.764 105.715 1.00 100.26 ?  204 ILE A CA  1 
ATOM   7929 C C   . ILE E 5 204 ? 122.774 139.043 105.249 1.00 100.26 ?  204 ILE A C   1 
ATOM   7930 O O   . ILE E 5 204 ? 122.768 140.052 105.964 1.00 100.26 ?  204 ILE A O   1 
ATOM   7931 C CB  . ILE E 5 204 ? 124.860 137.612 105.102 1.00 100.26 ?  204 ILE A CB  1 
ATOM   7932 C CG1 . ILE E 5 204 ? 125.594 136.429 105.735 1.00 100.26 ?  204 ILE A CG1 1 
ATOM   7933 C CG2 . ILE E 5 204 ? 125.665 138.889 105.276 1.00 100.26 ?  204 ILE A CG2 1 
ATOM   7934 C CD1 . ILE E 5 204 ? 126.872 136.053 105.021 1.00 100.26 ?  204 ILE A CD1 1 
ATOM   7935 N N   . LEU E 5 205 ? 122.193 139.029 104.047 1.00 100.41 ?  205 LEU A N   1 
ATOM   7936 C CA  . LEU E 5 205 ? 121.518 140.222 103.544 1.00 100.41 ?  205 LEU A CA  1 
ATOM   7937 C C   . LEU E 5 205 ? 120.312 140.580 104.403 1.00 100.41 ?  205 LEU A C   1 
ATOM   7938 O O   . LEU E 5 205 ? 120.098 141.754 104.723 1.00 100.41 ?  205 LEU A O   1 
ATOM   7939 C CB  . LEU E 5 205 ? 121.098 140.015 102.090 1.00 100.41 ?  205 LEU A CB  1 
ATOM   7940 C CG  . LEU E 5 205 ? 122.108 140.454 101.028 1.00 100.41 ?  205 LEU A CG  1 
ATOM   7941 C CD1 . LEU E 5 205 ? 121.445 140.535 99.662  1.00 100.41 ?  205 LEU A CD1 1 
ATOM   7942 C CD2 . LEU E 5 205 ? 122.738 141.787 101.402 1.00 100.41 ?  205 LEU A CD2 1 
ATOM   7943 N N   . PHE E 5 206 ? 119.515 139.580 104.788 1.00 97.13  ?  206 PHE A N   1 
ATOM   7944 C CA  . PHE E 5 206 ? 118.356 139.839 105.636 1.00 97.13  ?  206 PHE A CA  1 
ATOM   7945 C C   . PHE E 5 206 ? 118.782 140.399 106.986 1.00 97.13  ?  206 PHE A C   1 
ATOM   7946 O O   . PHE E 5 206 ? 118.201 141.373 107.481 1.00 97.13  ?  206 PHE A O   1 
ATOM   7947 C CB  . PHE E 5 206 ? 117.548 138.552 105.810 1.00 97.13  ?  206 PHE A CB  1 
ATOM   7948 C CG  . PHE E 5 206 ? 116.543 138.606 106.926 1.00 97.13  ?  206 PHE A CG  1 
ATOM   7949 C CD1 . PHE E 5 206 ? 115.349 139.289 106.768 1.00 97.13  ?  206 PHE A CD1 1 
ATOM   7950 C CD2 . PHE E 5 206 ? 116.789 137.966 108.129 1.00 97.13  ?  206 PHE A CD2 1 
ATOM   7951 C CE1 . PHE E 5 206 ? 114.421 139.335 107.790 1.00 97.13  ?  206 PHE A CE1 1 
ATOM   7952 C CE2 . PHE E 5 206 ? 115.866 138.010 109.155 1.00 97.13  ?  206 PHE A CE2 1 
ATOM   7953 C CZ  . PHE E 5 206 ? 114.681 138.696 108.986 1.00 97.13  ?  206 PHE A CZ  1 
ATOM   7954 N N   . CYS E 5 207 ? 119.810 139.799 107.593 1.00 94.69  ?  207 CYS A N   1 
ATOM   7955 C CA  . CYS E 5 207 ? 120.286 140.271 108.887 1.00 94.69  ?  207 CYS A CA  1 
ATOM   7956 C C   . CYS E 5 207 ? 120.827 141.690 108.793 1.00 94.69  ?  207 CYS A C   1 
ATOM   7957 O O   . CYS E 5 207 ? 120.545 142.524 109.658 1.00 94.69  ?  207 CYS A O   1 
ATOM   7958 C CB  . CYS E 5 207 ? 121.355 139.324 109.431 1.00 94.69  ?  207 CYS A CB  1 
ATOM   7959 S SG  . CYS E 5 207 ? 120.725 137.720 109.974 1.00 94.69  ?  207 CYS A SG  1 
ATOM   7960 N N   . SER E 5 208 ? 121.598 141.987 107.745 1.00 97.15  ?  208 SER A N   1 
ATOM   7961 C CA  . SER E 5 208 ? 122.148 143.328 107.587 1.00 97.15  ?  208 SER A CA  1 
ATOM   7962 C C   . SER E 5 208 ? 121.048 144.357 107.366 1.00 97.15  ?  208 SER A C   1 
ATOM   7963 O O   . SER E 5 208 ? 121.073 145.439 107.966 1.00 97.15  ?  208 SER A O   1 
ATOM   7964 C CB  . SER E 5 208 ? 123.143 143.350 106.428 1.00 97.15  ?  208 SER A CB  1 
ATOM   7965 O OG  . SER E 5 208 ? 124.302 142.597 106.739 1.00 97.15  ?  208 SER A OG  1 
ATOM   7966 N N   . ALA E 5 209 ? 120.072 144.039 106.511 1.00 97.72  ?  209 ALA A N   1 
ATOM   7967 C CA  . ALA E 5 209 ? 118.982 144.974 106.258 1.00 97.72  ?  209 ALA A CA  1 
ATOM   7968 C C   . ALA E 5 209 ? 118.171 145.227 107.521 1.00 97.72  ?  209 ALA A C   1 
ATOM   7969 O O   . ALA E 5 209 ? 117.835 146.376 107.831 1.00 97.72  ?  209 ALA A O   1 
ATOM   7970 C CB  . ALA E 5 209 ? 118.085 144.445 105.140 1.00 97.72  ?  209 ALA A CB  1 
ATOM   7971 N N   . ARG E 5 210 ? 117.855 144.167 108.269 1.00 96.23  ?  210 ARG A N   1 
ATOM   7972 C CA  . ARG E 5 210 ? 117.105 144.341 109.508 1.00 96.23  ?  210 ARG A CA  1 
ATOM   7973 C C   . ARG E 5 210 ? 117.906 145.130 110.534 1.00 96.23  ?  210 ARG A C   1 
ATOM   7974 O O   . ARG E 5 210 ? 117.352 145.982 111.236 1.00 96.23  ?  210 ARG A O   1 
ATOM   7975 C CB  . ARG E 5 210 ? 116.699 142.983 110.072 1.00 96.23  ?  210 ARG A CB  1 
ATOM   7976 C CG  . ARG E 5 210 ? 115.605 142.286 109.287 1.00 96.23  ?  210 ARG A CG  1 
ATOM   7977 C CD  . ARG E 5 210 ? 114.354 143.144 109.207 1.00 96.23  ?  210 ARG A CD  1 
ATOM   7978 N NE  . ARG E 5 210 ? 113.939 143.624 110.519 1.00 96.23  ?  210 ARG A NE  1 
ATOM   7979 C CZ  . ARG E 5 210 ? 113.229 142.916 111.387 1.00 96.23  ?  210 ARG A CZ  1 
ATOM   7980 N NH1 . ARG E 5 210 ? 112.837 141.682 111.116 1.00 96.23  1  210 ARG A NH1 1 
ATOM   7981 N NH2 . ARG E 5 210 ? 112.906 143.459 112.557 1.00 96.23  1  210 ARG A NH2 1 
ATOM   7982 N N   . ILE E 5 211 ? 119.211 144.865 110.635 1.00 93.60  ?  211 ILE A N   1 
ATOM   7983 C CA  . ILE E 5 211 ? 120.050 145.601 111.575 1.00 93.60  ?  211 ILE A CA  1 
ATOM   7984 C C   . ILE E 5 211 ? 120.040 147.083 111.235 1.00 93.60  ?  211 ILE A C   1 
ATOM   7985 O O   . ILE E 5 211 ? 119.849 147.935 112.109 1.00 93.60  ?  211 ILE A O   1 
ATOM   7986 C CB  . ILE E 5 211 ? 121.483 145.038 111.574 1.00 93.60  ?  211 ILE A CB  1 
ATOM   7987 C CG1 . ILE E 5 211 ? 121.576 143.790 112.448 1.00 93.60  ?  211 ILE A CG1 1 
ATOM   7988 C CG2 . ILE E 5 211 ? 122.473 146.087 112.056 1.00 93.60  ?  211 ILE A CG2 1 
ATOM   7989 C CD1 . ILE E 5 211 ? 122.957 143.177 112.464 1.00 93.60  ?  211 ILE A CD1 1 
ATOM   7990 N N   . ILE E 5 212 ? 120.229 147.412 109.956 1.00 100.14 ?  212 ILE A N   1 
ATOM   7991 C CA  . ILE E 5 212 ? 120.268 148.815 109.551 1.00 100.14 ?  212 ILE A CA  1 
ATOM   7992 C C   . ILE E 5 212 ? 118.923 149.480 109.816 1.00 100.14 ?  212 ILE A C   1 
ATOM   7993 O O   . ILE E 5 212 ? 118.853 150.578 110.384 1.00 100.14 ?  212 ILE A O   1 
ATOM   7994 C CB  . ILE E 5 212 ? 120.676 148.938 108.072 1.00 100.14 ?  212 ILE A CB  1 
ATOM   7995 C CG1 . ILE E 5 212 ? 122.088 148.389 107.852 1.00 100.14 ?  212 ILE A CG1 1 
ATOM   7996 C CG2 . ILE E 5 212 ? 120.593 150.384 107.615 1.00 100.14 ?  212 ILE A CG2 1 
ATOM   7997 C CD1 . ILE E 5 212 ? 123.065 148.734 108.949 1.00 100.14 ?  212 ILE A CD1 1 
ATOM   7998 N N   . TRP E 5 213 ? 117.832 148.815 109.424 1.00 105.34 ?  213 TRP A N   1 
ATOM   7999 C CA  . TRP E 5 213 ? 116.508 149.408 109.575 1.00 105.34 ?  213 TRP A CA  1 
ATOM   8000 C C   . TRP E 5 213 ? 116.165 149.629 111.043 1.00 105.34 ?  213 TRP A C   1 
ATOM   8001 O O   . TRP E 5 213 ? 115.649 150.687 111.416 1.00 105.34 ?  213 TRP A O   1 
ATOM   8002 C CB  . TRP E 5 213 ? 115.459 148.523 108.903 1.00 105.34 ?  213 TRP A CB  1 
ATOM   8003 C CG  . TRP E 5 213 ? 114.059 149.017 109.089 1.00 105.34 ?  213 TRP A CG  1 
ATOM   8004 C CD1 . TRP E 5 213 ? 113.535 150.189 108.626 1.00 105.34 ?  213 TRP A CD1 1 
ATOM   8005 C CD2 . TRP E 5 213 ? 113.001 148.354 109.791 1.00 105.34 ?  213 TRP A CD2 1 
ATOM   8006 N NE1 . TRP E 5 213 ? 112.217 150.296 108.996 1.00 105.34 ?  213 TRP A NE1 1 
ATOM   8007 C CE2 . TRP E 5 213 ? 111.864 149.183 109.712 1.00 105.34 ?  213 TRP A CE2 1 
ATOM   8008 C CE3 . TRP E 5 213 ? 112.904 147.140 110.478 1.00 105.34 ?  213 TRP A CE3 1 
ATOM   8009 C CZ2 . TRP E 5 213 ? 110.647 148.837 110.293 1.00 105.34 ?  213 TRP A CZ2 1 
ATOM   8010 C CZ3 . TRP E 5 213 ? 111.695 146.799 111.054 1.00 105.34 ?  213 TRP A CZ3 1 
ATOM   8011 C CH2 . TRP E 5 213 ? 110.582 147.644 110.958 1.00 105.34 ?  213 TRP A CH2 1 
ATOM   8012 N N   . SER E 5 214 ? 116.455 148.643 111.896 1.00 101.41 ?  214 SER A N   1 
ATOM   8013 C CA  . SER E 5 214 ? 116.144 148.781 113.313 1.00 101.41 ?  214 SER A CA  1 
ATOM   8014 C C   . SER E 5 214 ? 117.052 149.794 113.995 1.00 101.41 ?  214 SER A C   1 
ATOM   8015 O O   . SER E 5 214 ? 116.609 150.507 114.902 1.00 101.41 ?  214 SER A O   1 
ATOM   8016 C CB  . SER E 5 214 ? 116.249 147.425 114.009 1.00 101.41 ?  214 SER A CB  1 
ATOM   8017 O OG  . SER E 5 214 ? 116.041 147.553 115.404 1.00 101.41 ?  214 SER A OG  1 
ATOM   8018 N N   . LEU E 5 215 ? 118.315 149.879 113.579 1.00 101.07 ?  215 LEU A N   1 
ATOM   8019 C CA  . LEU E 5 215 ? 119.255 150.792 114.207 1.00 101.07 ?  215 LEU A CA  1 
ATOM   8020 C C   . LEU E 5 215 ? 119.075 152.228 113.739 1.00 101.07 ?  215 LEU A C   1 
ATOM   8021 O O   . LEU E 5 215 ? 119.556 153.147 114.410 1.00 101.07 ?  215 LEU A O   1 
ATOM   8022 C CB  . LEU E 5 215 ? 120.684 150.319 113.932 1.00 101.07 ?  215 LEU A CB  1 
ATOM   8023 C CG  . LEU E 5 215 ? 121.811 150.825 114.828 1.00 101.07 ?  215 LEU A CG  1 
ATOM   8024 C CD1 . LEU E 5 215 ? 121.559 150.416 116.266 1.00 101.07 ?  215 LEU A CD1 1 
ATOM   8025 C CD2 . LEU E 5 215 ? 123.136 150.267 114.346 1.00 101.07 ?  215 LEU A CD2 1 
ATOM   8026 N N   . ARG E 5 216 ? 118.398 152.448 112.610 1.00 108.37 ?  216 ARG A N   1 
ATOM   8027 C CA  . ARG E 5 216 ? 118.112 153.809 112.174 1.00 108.37 ?  216 ARG A CA  1 
ATOM   8028 C C   . ARG E 5 216 ? 116.677 154.244 112.441 1.00 108.37 ?  216 ARG A C   1 
ATOM   8029 O O   . ARG E 5 216 ? 116.413 155.451 112.474 1.00 108.37 ?  216 ARG A O   1 
ATOM   8030 C CB  . ARG E 5 216 ? 118.413 153.973 110.679 1.00 108.37 ?  216 ARG A CB  1 
ATOM   8031 C CG  . ARG E 5 216 ? 117.434 153.273 109.751 1.00 108.37 ?  216 ARG A CG  1 
ATOM   8032 C CD  . ARG E 5 216 ? 117.633 153.699 108.301 1.00 108.37 ?  216 ARG A CD  1 
ATOM   8033 N NE  . ARG E 5 216 ? 118.956 153.354 107.794 1.00 108.37 ?  216 ARG A NE  1 
ATOM   8034 C CZ  . ARG E 5 216 ? 119.968 154.206 107.692 1.00 108.37 ?  216 ARG A CZ  1 
ATOM   8035 N NH1 . ARG E 5 216 ? 119.846 155.472 108.055 1.00 108.37 1  216 ARG A NH1 1 
ATOM   8036 N NH2 . ARG E 5 216 ? 121.133 153.776 107.214 1.00 108.37 1  216 ARG A NH2 1 
ATOM   8037 N N   . GLN E 5 217 ? 115.746 153.305 112.631 1.00 108.83 ?  217 GLN A N   1 
ATOM   8038 C CA  . GLN E 5 217 ? 114.359 153.680 112.878 1.00 108.83 ?  217 GLN A CA  1 
ATOM   8039 C C   . GLN E 5 217 ? 114.135 154.173 114.300 1.00 108.83 ?  217 GLN A C   1 
ATOM   8040 O O   . GLN E 5 217 ? 113.158 154.886 114.548 1.00 108.83 ?  217 GLN A O   1 
ATOM   8041 C CB  . GLN E 5 217 ? 113.430 152.500 112.579 1.00 108.83 ?  217 GLN A CB  1 
ATOM   8042 C CG  . GLN E 5 217 ? 113.456 151.385 113.616 1.00 108.83 ?  217 GLN A CG  1 
ATOM   8043 C CD  . GLN E 5 217 ? 112.355 151.520 114.650 1.00 108.83 ?  217 GLN A CD  1 
ATOM   8044 O OE1 . GLN E 5 217 ? 112.604 151.007 115.850 1.00 108.83 ?  217 GLN A OE1 1 
ATOM   8045 N NE2 . GLN E 5 217 ? 111.293 152.076 114.374 1.00 108.83 ?  217 GLN A NE2 1 
ATOM   8046 N N   . ARG E 5 218 ? 115.073 153.834 115.194 1.00 106.61 ?  218 ARG A N   1 
ATOM   8047 C CA  . ARG E 5 218 ? 115.000 154.237 116.601 1.00 106.61 ?  218 ARG A CA  1 
ATOM   8048 C C   . ARG E 5 218 ? 115.987 155.346 116.900 1.00 106.61 ?  218 ARG A C   1 
ATOM   8049 O O   . ARG E 5 218 ? 116.293 155.601 118.059 1.00 106.61 ?  218 ARG A O   1 
ATOM   8050 C CB  . ARG E 5 218 ? 115.284 153.041 117.497 1.00 106.61 ?  218 ARG A CB  1 
ATOM   8051 C CG  . ARG E 5 218 ? 116.679 152.473 117.341 1.00 106.61 ?  218 ARG A CG  1 
ATOM   8052 C CD  . ARG E 5 218 ? 117.021 151.541 118.489 1.00 106.61 ?  218 ARG A CD  1 
ATOM   8053 N NE  . ARG E 5 218 ? 116.044 150.471 118.638 1.00 106.61 ?  218 ARG A NE  1 
ATOM   8054 C CZ  . ARG E 5 218 ? 115.477 150.140 119.790 1.00 106.61 ?  218 ARG A CZ  1 
ATOM   8055 N NH1 . ARG E 5 218 ? 115.788 150.801 120.897 1.00 106.61 1  218 ARG A NH1 1 
ATOM   8056 N NH2 . ARG E 5 218 ? 114.597 149.151 119.836 1.00 106.61 1  218 ARG A NH2 1 
ATOM   8057 N N   . GLN E 5 219 ? 116.515 155.984 115.876 1.00 111.14 ?  219 GLN A N   1 
ATOM   8058 C CA  . GLN E 5 219 ? 117.407 157.138 116.011 1.00 111.14 ?  219 GLN A CA  1 
ATOM   8059 C C   . GLN E 5 219 ? 118.643 156.813 116.848 1.00 111.14 ?  219 GLN A C   1 
ATOM   8060 O O   . GLN E 5 219 ? 119.109 157.631 117.643 1.00 111.14 ?  219 GLN A O   1 
ATOM   8061 C CB  . GLN E 5 219 ? 116.660 158.343 116.589 1.00 111.14 ?  219 GLN A CB  1 
ATOM   8062 C CG  . GLN E 5 219 ? 115.794 159.074 115.576 1.00 111.14 ?  219 GLN A CG  1 
ATOM   8063 C CD  . GLN E 5 219 ? 114.430 158.434 115.405 1.00 111.14 ?  219 GLN A CD  1 
ATOM   8064 O OE1 . GLN E 5 219 ? 113.939 157.741 116.296 1.00 111.14 ?  219 GLN A OE1 1 
ATOM   8065 N NE2 . GLN E 5 219 ? 113.810 158.663 114.253 1.00 111.14 ?  219 GLN A NE2 1 
ATOM   8066 N N   . MET E 5 220 ? 119.178 155.608 116.670 1.00 107.41 ?  220 MET A N   1 
ATOM   8067 C CA  . MET E 5 220 ? 120.463 155.253 117.255 1.00 107.41 ?  220 MET A CA  1 
ATOM   8068 C C   . MET E 5 220 ? 121.643 155.685 116.396 1.00 107.41 ?  220 MET A C   1 
ATOM   8069 O O   . MET E 5 220 ? 122.778 155.676 116.881 1.00 107.41 ?  220 MET A O   1 
ATOM   8070 C CB  . MET E 5 220 ? 120.538 153.743 117.499 1.00 107.41 ?  220 MET A CB  1 
ATOM   8071 C CG  . MET E 5 220 ? 119.689 153.260 118.655 1.00 107.41 ?  220 MET A CG  1 
ATOM   8072 S SD  . MET E 5 220 ? 120.423 151.860 119.519 1.00 107.41 ?  220 MET A SD  1 
ATOM   8073 C CE  . MET E 5 220 ? 122.014 152.539 119.976 1.00 107.41 ?  220 MET A CE  1 
ATOM   8074 N N   . ASP E 5 221 ? 121.401 156.068 115.143 1.00 116.30 ?  221 ASP A N   1 
ATOM   8075 C CA  . ASP E 5 221 ? 122.470 156.481 114.232 1.00 116.30 ?  221 ASP A CA  1 
ATOM   8076 C C   . ASP E 5 221 ? 122.754 157.976 114.396 1.00 116.30 ?  221 ASP A C   1 
ATOM   8077 O O   . ASP E 5 221 ? 122.555 158.798 113.499 1.00 116.30 ?  221 ASP A O   1 
ATOM   8078 C CB  . ASP E 5 221 ? 122.115 156.103 112.798 1.00 116.30 ?  221 ASP A CB  1 
ATOM   8079 C CG  . ASP E 5 221 ? 120.835 156.763 112.307 1.00 116.30 ?  221 ASP A CG  1 
ATOM   8080 O OD1 . ASP E 5 221 ? 120.179 157.480 113.091 1.00 116.30 ?  221 ASP A OD1 1 
ATOM   8081 O OD2 . ASP E 5 221 ? 120.484 156.561 111.125 1.00 116.30 -1 221 ASP A OD2 1 
ATOM   8082 N N   . ARG E 5 222 ? 123.254 158.316 115.582 1.00 118.36 ?  222 ARG A N   1 
ATOM   8083 C CA  . ARG E 5 222 ? 123.588 159.691 115.928 1.00 118.36 ?  222 ARG A CA  1 
ATOM   8084 C C   . ARG E 5 222 ? 125.086 159.918 116.068 1.00 118.36 ?  222 ARG A C   1 
ATOM   8085 O O   . ARG E 5 222 ? 125.634 160.826 115.437 1.00 118.36 ?  222 ARG A O   1 
ATOM   8086 C CB  . ARG E 5 222 ? 122.876 160.095 117.227 1.00 118.36 ?  222 ARG A CB  1 
ATOM   8087 C CG  . ARG E 5 222 ? 121.680 161.008 117.014 1.00 118.36 ?  222 ARG A CG  1 
ATOM   8088 C CD  . ARG E 5 222 ? 120.539 160.270 116.334 1.00 118.36 ?  222 ARG A CD  1 
ATOM   8089 N NE  . ARG E 5 222 ? 119.391 161.137 116.094 1.00 118.36 ?  222 ARG A NE  1 
ATOM   8090 C CZ  . ARG E 5 222 ? 118.426 161.364 116.974 1.00 118.36 ?  222 ARG A CZ  1 
ATOM   8091 N NH1 . ARG E 5 222 ? 118.438 160.804 118.173 1.00 118.36 1  222 ARG A NH1 1 
ATOM   8092 N NH2 . ARG E 5 222 ? 117.423 162.172 116.643 1.00 118.36 1  222 ARG A NH2 1 
ATOM   8093 N N   . HIS E 5 223 ? 125.766 159.115 116.880 1.00 117.48 ?  223 HIS A N   1 
ATOM   8094 C CA  . HIS E 5 223 ? 127.194 159.287 117.089 1.00 117.48 ?  223 HIS A CA  1 
ATOM   8095 C C   . HIS E 5 223 ? 127.993 158.480 116.067 1.00 117.48 ?  223 HIS A C   1 
ATOM   8096 O O   . HIS E 5 223 ? 127.448 157.718 115.266 1.00 117.48 ?  223 HIS A O   1 
ATOM   8097 C CB  . HIS E 5 223 ? 127.584 158.896 118.516 1.00 117.48 ?  223 HIS A CB  1 
ATOM   8098 C CG  . HIS E 5 223 ? 126.963 157.620 118.991 1.00 117.48 ?  223 HIS A CG  1 
ATOM   8099 N ND1 . HIS E 5 223 ? 127.498 156.394 119.203 1.00 117.48 ?  223 HIS A ND1 1 
ATOM   8100 C CD2 . HIS E 5 223 ? 125.630 157.519 119.327 1.00 117.48 ?  223 HIS A CD2 1 
ATOM   8101 C CE1 . HIS E 5 223 ? 126.485 155.582 119.651 1.00 117.48 ?  223 HIS A CE1 1 
ATOM   8102 N NE2 . HIS E 5 223 ? 125.368 156.284 119.716 1.00 117.48 ?  223 HIS A NE2 1 
ATOM   8103 N N   . ALA E 5 224 ? 129.315 158.663 116.106 1.00 119.44 ?  224 ALA A N   1 
ATOM   8104 C CA  . ALA E 5 224 ? 130.180 158.080 115.086 1.00 119.44 ?  224 ALA A CA  1 
ATOM   8105 C C   . ALA E 5 224 ? 130.295 156.568 115.221 1.00 119.44 ?  224 ALA A C   1 
ATOM   8106 O O   . ALA E 5 224 ? 130.520 155.878 114.221 1.00 119.44 ?  224 ALA A O   1 
ATOM   8107 C CB  . ALA E 5 224 ? 131.566 158.722 115.145 1.00 119.44 ?  224 ALA A CB  1 
ATOM   8108 N N   . LYS E 5 225 ? 130.163 156.035 116.438 1.00 115.06 ?  225 LYS A N   1 
ATOM   8109 C CA  . LYS E 5 225 ? 130.323 154.597 116.634 1.00 115.06 ?  225 LYS A CA  1 
ATOM   8110 C C   . LYS E 5 225 ? 129.236 153.809 115.913 1.00 115.06 ?  225 LYS A C   1 
ATOM   8111 O O   . LYS E 5 225 ? 129.516 152.773 115.296 1.00 115.06 ?  225 LYS A O   1 
ATOM   8112 C CB  . LYS E 5 225 ? 130.328 154.269 118.126 1.00 115.06 ?  225 LYS A CB  1 
ATOM   8113 C CG  . LYS E 5 225 ? 131.546 154.796 118.865 1.00 115.06 ?  225 LYS A CG  1 
ATOM   8114 C CD  . LYS E 5 225 ? 131.511 154.416 120.335 1.00 115.06 ?  225 LYS A CD  1 
ATOM   8115 C CE  . LYS E 5 225 ? 132.721 154.964 121.073 1.00 115.06 ?  225 LYS A CE  1 
ATOM   8116 N NZ  . LYS E 5 225 ? 132.697 154.611 122.519 1.00 115.06 1  225 LYS A NZ  1 
ATOM   8117 N N   . ILE E 5 226 ? 127.991 154.284 115.970 1.00 115.84 ?  226 ILE A N   1 
ATOM   8118 C CA  . ILE E 5 226 ? 126.901 153.571 115.312 1.00 115.84 ?  226 ILE A CA  1 
ATOM   8119 C C   . ILE E 5 226 ? 127.042 153.654 113.796 1.00 115.84 ?  226 ILE A C   1 
ATOM   8120 O O   . ILE E 5 226 ? 126.782 152.678 113.082 1.00 115.84 ?  226 ILE A O   1 
ATOM   8121 C CB  . ILE E 5 226 ? 125.543 154.112 115.792 1.00 115.84 ?  226 ILE A CB  1 
ATOM   8122 C CG1 . ILE E 5 226 ? 125.301 153.709 117.247 1.00 115.84 ?  226 ILE A CG1 1 
ATOM   8123 C CG2 . ILE E 5 226 ? 124.421 153.583 114.923 1.00 115.84 ?  226 ILE A CG2 1 
ATOM   8124 C CD1 . ILE E 5 226 ? 125.420 152.225 117.496 1.00 115.84 ?  226 ILE A CD1 1 
ATOM   8125 N N   . LYS E 5 227 ? 127.456 154.814 113.278 1.00 119.06 ?  227 LYS A N   1 
ATOM   8126 C CA  . LYS E 5 227 ? 127.706 154.930 111.844 1.00 119.06 ?  227 LYS A CA  1 
ATOM   8127 C C   . LYS E 5 227 ? 128.833 154.003 111.408 1.00 119.06 ?  227 LYS A C   1 
ATOM   8128 O O   . LYS E 5 227 ? 128.763 153.386 110.338 1.00 119.06 ?  227 LYS A O   1 
ATOM   8129 C CB  . LYS E 5 227 ? 128.034 156.377 111.479 1.00 119.06 ?  227 LYS A CB  1 
ATOM   8130 C CG  . LYS E 5 227 ? 126.914 157.362 111.755 1.00 119.06 ?  227 LYS A CG  1 
ATOM   8131 C CD  . LYS E 5 227 ? 125.745 157.135 110.812 1.00 119.06 ?  227 LYS A CD  1 
ATOM   8132 C CE  . LYS E 5 227 ? 124.620 158.119 111.079 1.00 119.06 ?  227 LYS A CE  1 
ATOM   8133 N NZ  . LYS E 5 227 ? 125.003 159.513 110.721 1.00 119.06 1  227 LYS A NZ  1 
ATOM   8134 N N   . ARG E 5 228 ? 129.884 153.899 112.223 1.00 120.07 ?  228 ARG A N   1 
ATOM   8135 C CA  . ARG E 5 228 ? 130.976 152.985 111.912 1.00 120.07 ?  228 ARG A CA  1 
ATOM   8136 C C   . ARG E 5 228 ? 130.497 151.540 111.907 1.00 120.07 ?  228 ARG A C   1 
ATOM   8137 O O   . ARG E 5 228 ? 130.875 150.759 111.030 1.00 120.07 ?  228 ARG A O   1 
ATOM   8138 C CB  . ARG E 5 228 ? 132.118 153.176 112.909 1.00 120.07 ?  228 ARG A CB  1 
ATOM   8139 C CG  . ARG E 5 228 ? 133.238 152.157 112.784 1.00 120.07 ?  228 ARG A CG  1 
ATOM   8140 C CD  . ARG E 5 228 ? 134.508 152.665 113.444 1.00 120.07 ?  228 ARG A CD  1 
ATOM   8141 N NE  . ARG E 5 228 ? 134.371 152.761 114.892 1.00 120.07 ?  228 ARG A NE  1 
ATOM   8142 C CZ  . ARG E 5 228 ? 135.188 152.184 115.763 1.00 120.07 ?  228 ARG A CZ  1 
ATOM   8143 N NH1 . ARG E 5 228 ? 136.212 151.447 115.366 1.00 120.07 1  228 ARG A NH1 1 
ATOM   8144 N NH2 . ARG E 5 228 ? 134.973 152.354 117.064 1.00 120.07 1  228 ARG A NH2 1 
ATOM   8145 N N   . ALA E 5 229 ? 129.654 151.167 112.872 1.00 115.05 ?  229 ALA A N   1 
ATOM   8146 C CA  . ALA E 5 229 ? 129.109 149.813 112.889 1.00 115.05 ?  229 ALA A CA  1 
ATOM   8147 C C   . ALA E 5 229 ? 128.245 149.547 111.661 1.00 115.05 ?  229 ALA A C   1 
ATOM   8148 O O   . ALA E 5 229 ? 128.314 148.466 111.062 1.00 115.05 ?  229 ALA A O   1 
ATOM   8149 C CB  . ALA E 5 229 ? 128.304 149.587 114.168 1.00 115.05 ?  229 ALA A CB  1 
ATOM   8150 N N   . ILE E 5 230 ? 127.424 150.524 111.274 1.00 114.85 ?  230 ILE A N   1 
ATOM   8151 C CA  . ILE E 5 230 ? 126.551 150.358 110.116 1.00 114.85 ?  230 ILE A CA  1 
ATOM   8152 C C   . ILE E 5 230 ? 127.374 150.182 108.847 1.00 114.85 ?  230 ILE A C   1 
ATOM   8153 O O   . ILE E 5 230 ? 127.129 149.267 108.048 1.00 114.85 ?  230 ILE A O   1 
ATOM   8154 C CB  . ILE E 5 230 ? 125.588 151.554 110.006 1.00 114.85 ?  230 ILE A CB  1 
ATOM   8155 C CG1 . ILE E 5 230 ? 124.435 151.402 110.998 1.00 114.85 ?  230 ILE A CG1 1 
ATOM   8156 C CG2 . ILE E 5 230 ? 125.071 151.704 108.583 1.00 114.85 ?  230 ILE A CG2 1 
ATOM   8157 C CD1 . ILE E 5 230 ? 123.473 152.564 110.992 1.00 114.85 ?  230 ILE A CD1 1 
ATOM   8158 N N   . THR E 5 231 ? 128.376 151.042 108.649 1.00 117.86 ?  231 THR A N   1 
ATOM   8159 C CA  . THR E 5 231 ? 129.195 150.925 107.449 1.00 117.86 ?  231 THR A CA  1 
ATOM   8160 C C   . THR E 5 231 ? 130.063 149.674 107.493 1.00 117.86 ?  231 THR A C   1 
ATOM   8161 O O   . THR E 5 231 ? 130.400 149.122 106.443 1.00 117.86 ?  231 THR A O   1 
ATOM   8162 C CB  . THR E 5 231 ? 130.048 152.183 107.253 1.00 117.86 ?  231 THR A CB  1 
ATOM   8163 O OG1 . THR E 5 231 ? 130.568 152.203 105.918 1.00 117.86 ?  231 THR A OG1 1 
ATOM   8164 C CG2 . THR E 5 231 ? 131.207 152.229 108.238 1.00 117.86 ?  231 THR A CG2 1 
ATOM   8165 N N   . PHE E 5 232 ? 130.400 149.189 108.691 1.00 117.08 ?  232 PHE A N   1 
ATOM   8166 C CA  . PHE E 5 232 ? 131.152 147.946 108.809 1.00 117.08 ?  232 PHE A CA  1 
ATOM   8167 C C   . PHE E 5 232 ? 130.301 146.754 108.392 1.00 117.08 ?  232 PHE A C   1 
ATOM   8168 O O   . PHE E 5 232 ? 130.772 145.865 107.676 1.00 117.08 ?  232 PHE A O   1 
ATOM   8169 C CB  . PHE E 5 232 ? 131.646 147.791 110.245 1.00 117.08 ?  232 PHE A CB  1 
ATOM   8170 C CG  . PHE E 5 232 ? 132.955 148.477 110.512 1.00 117.08 ?  232 PHE A CG  1 
ATOM   8171 C CD1 . PHE E 5 232 ? 133.459 149.411 109.619 1.00 117.08 ?  232 PHE A CD1 1 
ATOM   8172 C CD2 . PHE E 5 232 ? 133.686 148.184 111.648 1.00 117.08 ?  232 PHE A CD2 1 
ATOM   8173 C CE1 . PHE E 5 232 ? 134.664 150.046 109.858 1.00 117.08 ?  232 PHE A CE1 1 
ATOM   8174 C CE2 . PHE E 5 232 ? 134.886 148.823 111.898 1.00 117.08 ?  232 PHE A CE2 1 
ATOM   8175 C CZ  . PHE E 5 232 ? 135.379 149.750 110.999 1.00 117.08 ?  232 PHE A CZ  1 
ATOM   8176 N N   . ILE E 5 233 ? 129.036 146.733 108.813 1.00 110.87 ?  233 ILE A N   1 
ATOM   8177 C CA  . ILE E 5 233 ? 128.116 145.695 108.353 1.00 110.87 ?  233 ILE A CA  1 
ATOM   8178 C C   . ILE E 5 233 ? 127.958 145.767 106.838 1.00 110.87 ?  233 ILE A C   1 
ATOM   8179 O O   . ILE E 5 233 ? 127.983 144.744 106.135 1.00 110.87 ?  233 ILE A O   1 
ATOM   8180 C CB  . ILE E 5 233 ? 126.761 145.828 109.070 1.00 110.87 ?  233 ILE A CB  1 
ATOM   8181 C CG1 . ILE E 5 233 ? 126.893 145.436 110.542 1.00 110.87 ?  233 ILE A CG1 1 
ATOM   8182 C CG2 . ILE E 5 233 ? 125.714 144.976 108.389 1.00 110.87 ?  233 ILE A CG2 1 
ATOM   8183 C CD1 . ILE E 5 233 ? 127.172 143.968 110.756 1.00 110.87 ?  233 ILE A CD1 1 
ATOM   8184 N N   . MET E 5 234 ? 127.801 146.985 106.314 1.00 115.79 ?  234 MET A N   1 
ATOM   8185 C CA  . MET E 5 234 ? 127.617 147.158 104.877 1.00 115.79 ?  234 MET A CA  1 
ATOM   8186 C C   . MET E 5 234 ? 128.831 146.662 104.099 1.00 115.79 ?  234 MET A C   1 
ATOM   8187 O O   . MET E 5 234 ? 128.687 145.976 103.080 1.00 115.79 ?  234 MET A O   1 
ATOM   8188 C CB  . MET E 5 234 ? 127.341 148.628 104.563 1.00 115.79 ?  234 MET A CB  1 
ATOM   8189 C CG  . MET E 5 234 ? 126.975 148.906 103.117 1.00 115.79 ?  234 MET A CG  1 
ATOM   8190 S SD  . MET E 5 234 ? 125.396 148.156 102.673 1.00 115.79 ?  234 MET A SD  1 
ATOM   8191 C CE  . MET E 5 234 ? 125.571 148.009 100.898 1.00 115.79 ?  234 MET A CE  1 
ATOM   8192 N N   . VAL E 5 235 ? 130.039 146.990 104.568 1.00 115.75 ?  235 VAL A N   1 
ATOM   8193 C CA  . VAL E 5 235 ? 131.239 146.564 103.859 1.00 115.75 ?  235 VAL A CA  1 
ATOM   8194 C C   . VAL E 5 235 ? 131.450 145.062 104.009 1.00 115.75 ?  235 VAL A C   1 
ATOM   8195 O O   . VAL E 5 235 ? 131.996 144.422 103.109 1.00 115.75 ?  235 VAL A O   1 
ATOM   8196 C CB  . VAL E 5 235 ? 132.471 147.369 104.321 1.00 115.75 ?  235 VAL A CB  1 
ATOM   8197 C CG1 . VAL E 5 235 ? 132.874 147.001 105.734 1.00 115.75 ?  235 VAL A CG1 1 
ATOM   8198 C CG2 . VAL E 5 235 ? 133.635 147.173 103.357 1.00 115.75 ?  235 VAL A CG2 1 
ATOM   8199 N N   . VAL E 5 236 ? 131.018 144.468 105.125 1.00 113.27 ?  236 VAL A N   1 
ATOM   8200 C CA  . VAL E 5 236 ? 131.048 143.011 105.239 1.00 113.27 ?  236 VAL A CA  1 
ATOM   8201 C C   . VAL E 5 236 ? 130.177 142.382 104.159 1.00 113.27 ?  236 VAL A C   1 
ATOM   8202 O O   . VAL E 5 236 ? 130.586 141.436 103.469 1.00 113.27 ?  236 VAL A O   1 
ATOM   8203 C CB  . VAL E 5 236 ? 130.600 142.569 106.644 1.00 113.27 ?  236 VAL A CB  1 
ATOM   8204 C CG1 . VAL E 5 236 ? 130.199 141.106 106.632 1.00 113.27 ?  236 VAL A CG1 1 
ATOM   8205 C CG2 . VAL E 5 236 ? 131.703 142.805 107.655 1.00 113.27 ?  236 VAL A CG2 1 
ATOM   8206 N N   . ALA E 5 237 ? 128.961 142.909 103.994 1.00 114.14 ?  237 ALA A N   1 
ATOM   8207 C CA  . ALA E 5 237 ? 128.070 142.385 102.962 1.00 114.14 ?  237 ALA A CA  1 
ATOM   8208 C C   . ALA E 5 237 ? 128.670 142.560 101.571 1.00 114.14 ?  237 ALA A C   1 
ATOM   8209 O O   . ALA E 5 237 ? 128.623 141.639 100.744 1.00 114.14 ?  237 ALA A O   1 
ATOM   8210 C CB  . ALA E 5 237 ? 126.706 143.068 103.050 1.00 114.14 ?  237 ALA A CB  1 
ATOM   8211 N N   . ILE E 5 238 ? 129.251 143.731 101.301 1.00 117.29 ?  238 ILE A N   1 
ATOM   8212 C CA  . ILE E 5 238 ? 129.849 143.985 99.992  1.00 117.29 ?  238 ILE A CA  1 
ATOM   8213 C C   . ILE E 5 238 ? 131.032 143.057 99.743  1.00 117.29 ?  238 ILE A C   1 
ATOM   8214 O O   . ILE E 5 238 ? 131.213 142.554 98.630  1.00 117.29 ?  238 ILE A O   1 
ATOM   8215 C CB  . ILE E 5 238 ? 130.247 145.465 99.854  1.00 117.29 ?  238 ILE A CB  1 
ATOM   8216 N N   . VAL E 5 239 ? 131.864 142.827 100.762 1.00 116.86 ?  239 VAL A N   1 
ATOM   8217 C CA  . VAL E 5 239 ? 133.006 141.931 100.605 1.00 116.86 ?  239 VAL A CA  1 
ATOM   8218 C C   . VAL E 5 239 ? 132.534 140.518 100.297 1.00 116.86 ?  239 VAL A C   1 
ATOM   8219 O O   . VAL E 5 239 ? 133.059 139.858 99.392  1.00 116.86 ?  239 VAL A O   1 
ATOM   8220 C CB  . VAL E 5 239 ? 133.896 141.971 101.861 1.00 116.86 ?  239 VAL A CB  1 
ATOM   8221 C CG1 . VAL E 5 239 ? 134.832 140.774 101.889 1.00 116.86 ?  239 VAL A CG1 1 
ATOM   8222 C CG2 . VAL E 5 239 ? 134.693 143.263 101.900 1.00 116.86 ?  239 VAL A CG2 1 
ATOM   8223 N N   . PHE E 5 240 ? 131.529 140.035 101.032 1.00 114.68 ?  240 PHE A N   1 
ATOM   8224 C CA  . PHE E 5 240 ? 131.001 138.702 100.760 1.00 114.68 ?  240 PHE A CA  1 
ATOM   8225 C C   . PHE E 5 240 ? 130.477 138.606 99.332  1.00 114.68 ?  240 PHE A C   1 
ATOM   8226 O O   . PHE E 5 240 ? 130.773 137.645 98.608  1.00 114.68 ?  240 PHE A O   1 
ATOM   8227 C CB  . PHE E 5 240 ? 129.902 138.361 101.768 1.00 114.68 ?  240 PHE A CB  1 
ATOM   8228 C CG  . PHE E 5 240 ? 129.380 136.955 101.653 1.00 114.68 ?  240 PHE A CG  1 
ATOM   8229 C CD1 . PHE E 5 240 ? 128.355 136.649 100.774 1.00 114.68 ?  240 PHE A CD1 1 
ATOM   8230 C CD2 . PHE E 5 240 ? 129.911 135.942 102.432 1.00 114.68 ?  240 PHE A CD2 1 
ATOM   8231 C CE1 . PHE E 5 240 ? 127.874 135.359 100.670 1.00 114.68 ?  240 PHE A CE1 1 
ATOM   8232 C CE2 . PHE E 5 240 ? 129.433 134.651 102.332 1.00 114.68 ?  240 PHE A CE2 1 
ATOM   8233 C CZ  . PHE E 5 240 ? 128.414 134.359 101.450 1.00 114.68 ?  240 PHE A CZ  1 
ATOM   8234 N N   . VAL E 5 241 ? 129.706 139.610 98.905  1.00 120.60 ?  241 VAL A N   1 
ATOM   8235 C CA  . VAL E 5 241 ? 129.115 139.579 97.570  1.00 120.60 ?  241 VAL A CA  1 
ATOM   8236 C C   . VAL E 5 241 ? 130.202 139.599 96.502  1.00 120.60 ?  241 VAL A C   1 
ATOM   8237 O O   . VAL E 5 241 ? 130.170 138.816 95.548  1.00 120.60 ?  241 VAL A O   1 
ATOM   8238 C CB  . VAL E 5 241 ? 128.125 140.744 97.393  1.00 120.60 ?  241 VAL A CB  1 
ATOM   8239 C CG1 . VAL E 5 241 ? 127.746 140.902 95.929  1.00 120.60 ?  241 VAL A CG1 1 
ATOM   8240 C CG2 . VAL E 5 241 ? 126.887 140.518 98.243  1.00 120.60 ?  241 VAL A CG2 1 
ATOM   8241 N N   . ILE E 5 242 ? 131.189 140.486 96.650  1.00 123.05 ?  242 ILE A N   1 
ATOM   8242 C CA  . ILE E 5 242 ? 132.210 140.616 95.615  1.00 123.05 ?  242 ILE A CA  1 
ATOM   8243 C C   . ILE E 5 242 ? 133.105 139.384 95.577  1.00 123.05 ?  242 ILE A C   1 
ATOM   8244 O O   . ILE E 5 242 ? 133.612 139.013 94.511  1.00 123.05 ?  242 ILE A O   1 
ATOM   8245 C CB  . ILE E 5 242 ? 133.024 141.911 95.810  1.00 123.05 ?  242 ILE A CB  1 
ATOM   8246 C CG1 . ILE E 5 242 ? 133.866 142.204 94.567  1.00 123.05 ?  242 ILE A CG1 1 
ATOM   8247 C CG2 . ILE E 5 242 ? 133.921 141.822 97.033  1.00 123.05 ?  242 ILE A CG2 1 
ATOM   8248 C CD1 . ILE E 5 242 ? 133.047 142.523 93.336  1.00 123.05 ?  242 ILE A CD1 1 
ATOM   8249 N N   . CYS E 5 243 ? 133.314 138.722 96.719  1.00 126.54 ?  243 CYS A N   1 
ATOM   8250 C CA  . CYS E 5 243 ? 134.148 137.526 96.717  1.00 126.54 ?  243 CYS A CA  1 
ATOM   8251 C C   . CYS E 5 243 ? 133.421 136.334 96.109  1.00 126.54 ?  243 CYS A C   1 
ATOM   8252 O O   . CYS E 5 243 ? 134.025 135.555 95.362  1.00 126.54 ?  243 CYS A O   1 
ATOM   8253 C CB  . CYS E 5 243 ? 134.618 137.203 98.135  1.00 126.54 ?  243 CYS A CB  1 
ATOM   8254 S SG  . CYS E 5 243 ? 135.744 138.424 98.847  1.00 126.54 ?  243 CYS A SG  1 
ATOM   8255 N N   . PHE E 5 244 ? 132.132 136.165 96.407  1.00 124.92 ?  244 PHE A N   1 
ATOM   8256 C CA  . PHE E 5 244 ? 131.439 134.944 96.019  1.00 124.92 ?  244 PHE A CA  1 
ATOM   8257 C C   . PHE E 5 244 ? 130.442 135.115 94.879  1.00 124.92 ?  244 PHE A C   1 
ATOM   8258 O O   . PHE E 5 244 ? 129.713 134.165 94.573  1.00 124.92 ?  244 PHE A O   1 
ATOM   8259 C CB  . PHE E 5 244 ? 130.739 134.335 97.236  1.00 124.92 ?  244 PHE A CB  1 
ATOM   8260 C CG  . PHE E 5 244 ? 131.682 133.707 98.217  1.00 124.92 ?  244 PHE A CG  1 
ATOM   8261 C CD1 . PHE E 5 244 ? 132.253 132.475 97.956  1.00 124.92 ?  244 PHE A CD1 1 
ATOM   8262 C CD2 . PHE E 5 244 ? 132.005 134.352 99.397  1.00 124.92 ?  244 PHE A CD2 1 
ATOM   8263 C CE1 . PHE E 5 244 ? 133.124 131.896 98.854  1.00 124.92 ?  244 PHE A CE1 1 
ATOM   8264 C CE2 . PHE E 5 244 ? 132.874 133.777 100.298 1.00 124.92 ?  244 PHE A CE2 1 
ATOM   8265 C CZ  . PHE E 5 244 ? 133.436 132.549 100.027 1.00 124.92 ?  244 PHE A CZ  1 
ATOM   8266 N N   . LEU E 5 245 ? 130.382 136.281 94.240  1.00 134.12 ?  245 LEU A N   1 
ATOM   8267 C CA  . LEU E 5 245 ? 129.514 136.449 93.079  1.00 134.12 ?  245 LEU A CA  1 
ATOM   8268 C C   . LEU E 5 245 ? 130.106 135.867 91.797  1.00 134.12 ?  245 LEU A C   1 
ATOM   8269 O O   . LEU E 5 245 ? 129.455 135.030 91.159  1.00 134.12 ?  245 LEU A O   1 
ATOM   8270 C CB  . LEU E 5 245 ? 129.183 137.931 92.874  1.00 134.12 ?  245 LEU A CB  1 
ATOM   8271 C CG  . LEU E 5 245 ? 128.016 138.264 91.941  1.00 134.12 ?  245 LEU A CG  1 
ATOM   8272 C CD1 . LEU E 5 245 ? 126.677 138.058 92.626  1.00 134.12 ?  245 LEU A CD1 1 
ATOM   8273 C CD2 . LEU E 5 245 ? 128.140 139.688 91.417  1.00 134.12 ?  245 LEU A CD2 1 
ATOM   8274 N N   . PRO E 5 246 ? 131.313 136.278 91.374  1.00 139.79 ?  246 PRO A N   1 
ATOM   8275 C CA  . PRO E 5 246 ? 131.762 135.900 90.021  1.00 139.79 ?  246 PRO A CA  1 
ATOM   8276 C C   . PRO E 5 246 ? 131.891 134.402 89.803  1.00 139.79 ?  246 PRO A C   1 
ATOM   8277 O O   . PRO E 5 246 ? 131.618 133.920 88.696  1.00 139.79 ?  246 PRO A O   1 
ATOM   8278 C CB  . PRO E 5 246 ? 133.113 136.617 89.896  1.00 139.79 ?  246 PRO A CB  1 
ATOM   8279 C CG  . PRO E 5 246 ? 133.588 136.754 91.288  1.00 139.79 ?  246 PRO A CG  1 
ATOM   8280 C CD  . PRO E 5 246 ? 132.359 137.036 92.088  1.00 139.79 ?  246 PRO A CD  1 
ATOM   8281 N N   . SER E 5 247 ? 132.299 133.646 90.824  1.00 143.65 ?  247 SER A N   1 
ATOM   8282 C CA  . SER E 5 247 ? 132.431 132.201 90.663  1.00 143.65 ?  247 SER A CA  1 
ATOM   8283 C C   . SER E 5 247 ? 131.076 131.552 90.412  1.00 143.65 ?  247 SER A C   1 
ATOM   8284 O O   . SER E 5 247 ? 130.926 130.721 89.508  1.00 143.65 ?  247 SER A O   1 
ATOM   8285 C CB  . SER E 5 247 ? 133.103 131.596 91.897  1.00 143.65 ?  247 SER A CB  1 
ATOM   8286 O OG  . SER E 5 247 ? 132.577 132.152 93.088  1.00 143.65 ?  247 SER A OG  1 
ATOM   8287 N N   . VAL E 5 248 ? 130.068 131.933 91.196  1.00 142.83 ?  248 VAL A N   1 
ATOM   8288 C CA  . VAL E 5 248 ? 128.730 131.389 90.990  1.00 142.83 ?  248 VAL A CA  1 
ATOM   8289 C C   . VAL E 5 248 ? 128.176 131.843 89.647  1.00 142.83 ?  248 VAL A C   1 
ATOM   8290 O O   . VAL E 5 248 ? 127.472 131.091 88.963  1.00 142.83 ?  248 VAL A O   1 
ATOM   8291 C CB  . VAL E 5 248 ? 127.807 131.787 92.156  1.00 142.83 ?  248 VAL A CB  1 
ATOM   8292 C CG1 . VAL E 5 248 ? 126.411 131.222 91.951  1.00 142.83 ?  248 VAL A CG1 1 
ATOM   8293 C CG2 . VAL E 5 248 ? 128.393 131.303 93.470  1.00 142.83 ?  248 VAL A CG2 1 
ATOM   8294 N N   . VAL E 5 249 ? 128.495 133.074 89.241  1.00 147.87 ?  249 VAL A N   1 
ATOM   8295 C CA  . VAL E 5 249 ? 128.006 133.589 87.964  1.00 147.87 ?  249 VAL A CA  1 
ATOM   8296 C C   . VAL E 5 249 ? 128.576 132.775 86.808  1.00 147.87 ?  249 VAL A C   1 
ATOM   8297 O O   . VAL E 5 249 ? 127.847 132.349 85.904  1.00 147.87 ?  249 VAL A O   1 
ATOM   8298 C CB  . VAL E 5 249 ? 128.344 135.084 87.825  1.00 147.87 ?  249 VAL A CB  1 
ATOM   8299 C CG1 . VAL E 5 249 ? 128.221 135.526 86.375  1.00 147.87 ?  249 VAL A CG1 1 
ATOM   8300 C CG2 . VAL E 5 249 ? 127.440 135.916 88.719  1.00 147.87 ?  249 VAL A CG2 1 
ATOM   8301 N N   . VAL E 5 250 ? 129.888 132.530 86.825  1.00 152.19 ?  250 VAL A N   1 
ATOM   8302 C CA  . VAL E 5 250 ? 130.483 131.761 85.737  1.00 152.19 ?  250 VAL A CA  1 
ATOM   8303 C C   . VAL E 5 250 ? 130.021 130.308 85.787  1.00 152.19 ?  250 VAL A C   1 
ATOM   8304 O O   . VAL E 5 250 ? 129.857 129.669 84.740  1.00 152.19 ?  250 VAL A O   1 
ATOM   8305 C CB  . VAL E 5 250 ? 132.020 131.879 85.746  1.00 152.19 ?  250 VAL A CB  1 
ATOM   8306 C CG1 . VAL E 5 250 ? 132.442 133.330 85.557  1.00 152.19 ?  250 VAL A CG1 1 
ATOM   8307 C CG2 . VAL E 5 250 ? 132.612 131.309 87.018  1.00 152.19 ?  250 VAL A CG2 1 
ATOM   8308 N N   . ARG E 5 251 ? 129.781 129.762 86.985  1.00 156.01 ?  251 ARG A N   1 
ATOM   8309 C CA  . ARG E 5 251 ? 129.315 128.381 87.060  1.00 156.01 ?  251 ARG A CA  1 
ATOM   8310 C C   . ARG E 5 251 ? 127.893 128.238 86.527  1.00 156.01 ?  251 ARG A C   1 
ATOM   8311 O O   . ARG E 5 251 ? 127.583 127.266 85.830  1.00 156.01 ?  251 ARG A O   1 
ATOM   8312 C CB  . ARG E 5 251 ? 129.413 127.859 88.492  1.00 156.01 ?  251 ARG A CB  1 
ATOM   8313 C CG  . ARG E 5 251 ? 129.339 126.342 88.571  1.00 156.01 ?  251 ARG A CG  1 
ATOM   8314 C CD  . ARG E 5 251 ? 130.727 125.720 88.600  1.00 156.01 ?  251 ARG A CD  1 
ATOM   8315 N NE  . ARG E 5 251 ? 130.688 124.277 88.808  1.00 156.01 ?  251 ARG A NE  1 
ATOM   8316 C CZ  . ARG E 5 251 ? 131.334 123.391 88.061  1.00 156.01 ?  251 ARG A CZ  1 
ATOM   8317 N NH1 . ARG E 5 251 ? 132.110 123.767 87.058  1.00 156.01 1  251 ARG A NH1 1 
ATOM   8318 N NH2 . ARG E 5 251 ? 131.206 122.096 88.335  1.00 156.01 1  251 ARG A NH2 1 
ATOM   8319 N N   . ILE E 5 252 ? 127.008 129.187 86.835  1.00 156.64 ?  252 ILE A N   1 
ATOM   8320 C CA  . ILE E 5 252 ? 125.661 129.106 86.277  1.00 156.64 ?  252 ILE A CA  1 
ATOM   8321 C C   . ILE E 5 252 ? 125.693 129.381 84.777  1.00 156.64 ?  252 ILE A C   1 
ATOM   8322 O O   . ILE E 5 252 ? 124.889 128.830 84.017  1.00 156.64 ?  252 ILE A O   1 
ATOM   8323 C CB  . ILE E 5 252 ? 124.689 130.045 87.019  1.00 156.64 ?  252 ILE A CB  1 
ATOM   8324 C CG1 . ILE E 5 252 ? 125.107 131.508 86.881  1.00 156.64 ?  252 ILE A CG1 1 
ATOM   8325 C CG2 . ILE E 5 252 ? 124.586 129.652 88.486  1.00 156.64 ?  252 ILE A CG2 1 
ATOM   8326 C CD1 . ILE E 5 252 ? 124.072 132.488 87.388  1.00 156.64 ?  252 ILE A CD1 1 
ATOM   8327 N N   . HIS E 5 253 ? 126.633 130.214 84.322  1.00 160.85 ?  253 HIS A N   1 
ATOM   8328 C CA  . HIS E 5 253 ? 126.796 130.429 82.887  1.00 160.85 ?  253 HIS A CA  1 
ATOM   8329 C C   . HIS E 5 253 ? 127.195 129.139 82.177  1.00 160.85 ?  253 HIS A C   1 
ATOM   8330 O O   . HIS E 5 253 ? 126.640 128.794 81.125  1.00 160.85 ?  253 HIS A O   1 
ATOM   8331 C CB  . HIS E 5 253 ? 127.834 131.525 82.641  1.00 160.85 ?  253 HIS A CB  1 
ATOM   8332 C CG  . HIS E 5 253 ? 127.962 131.928 81.205  1.00 160.85 ?  253 HIS A CG  1 
ATOM   8333 N ND1 . HIS E 5 253 ? 127.363 132.917 80.500  1.00 160.85 ?  253 HIS A ND1 1 
ATOM   8334 C CD2 . HIS E 5 253 ? 128.795 131.279 80.321  1.00 160.85 ?  253 HIS A CD2 1 
ATOM   8335 C CE1 . HIS E 5 253 ? 127.841 132.846 79.215  1.00 160.85 ?  253 HIS A CE1 1 
ATOM   8336 N NE2 . HIS E 5 253 ? 128.704 131.849 79.133  1.00 160.85 ?  253 HIS A NE2 1 
ATOM   8337 N N   . ILE E 5 254 ? 128.159 128.406 82.740  1.00 162.74 ?  254 ILE A N   1 
ATOM   8338 C CA  . ILE E 5 254 ? 128.582 127.167 82.095  1.00 162.74 ?  254 ILE A CA  1 
ATOM   8339 C C   . ILE E 5 254 ? 127.507 126.093 82.228  1.00 162.74 ?  254 ILE A C   1 
ATOM   8340 O O   . ILE E 5 254 ? 127.379 125.231 81.354  1.00 162.74 ?  254 ILE A O   1 
ATOM   8341 C CB  . ILE E 5 254 ? 129.943 126.687 82.635  1.00 162.74 ?  254 ILE A CB  1 
ATOM   8342 C CG1 . ILE E 5 254 ? 129.876 126.372 84.124  1.00 162.74 ?  254 ILE A CG1 1 
ATOM   8343 C CG2 . ILE E 5 254 ? 131.009 127.733 82.382  1.00 162.74 ?  254 ILE A CG2 1 
ATOM   8344 C CD1 . ILE E 5 254 ? 131.108 125.686 84.647  1.00 162.74 ?  254 ILE A CD1 1 
ATOM   8345 N N   . PHE E 5 255 ? 126.715 126.119 83.305  1.00 162.96 ?  255 PHE A N   1 
ATOM   8346 C CA  . PHE E 5 255 ? 125.563 125.222 83.384  1.00 162.96 ?  255 PHE A CA  1 
ATOM   8347 C C   . PHE E 5 255 ? 124.540 125.532 82.297  1.00 162.96 ?  255 PHE A C   1 
ATOM   8348 O O   . PHE E 5 255 ? 123.956 124.617 81.706  1.00 162.96 ?  255 PHE A O   1 
ATOM   8349 C CB  . PHE E 5 255 ? 124.916 125.295 84.767  1.00 162.96 ?  255 PHE A CB  1 
ATOM   8350 N N   . TRP E 5 256 ? 124.298 126.817 82.029  1.00 168.99 ?  256 TRP A N   1 
ATOM   8351 C CA  . TRP E 5 256 ? 123.398 127.184 80.940  1.00 168.99 ?  256 TRP A CA  1 
ATOM   8352 C C   . TRP E 5 256 ? 123.950 126.722 79.596  1.00 168.99 ?  256 TRP A C   1 
ATOM   8353 O O   . TRP E 5 256 ? 123.202 126.231 78.742  1.00 168.99 ?  256 TRP A O   1 
ATOM   8354 C CB  . TRP E 5 256 ? 123.164 128.695 80.939  1.00 168.99 ?  256 TRP A CB  1 
ATOM   8355 C CG  . TRP E 5 256 ? 122.492 129.204 79.700  1.00 168.99 ?  256 TRP A CG  1 
ATOM   8356 C CD1 . TRP E 5 256 ? 121.331 128.745 79.150  1.00 168.99 ?  256 TRP A CD1 1 
ATOM   8357 C CD2 . TRP E 5 256 ? 122.935 130.279 78.861  1.00 168.99 ?  256 TRP A CD2 1 
ATOM   8358 N NE1 . TRP E 5 256 ? 121.026 129.462 78.019  1.00 168.99 ?  256 TRP A NE1 1 
ATOM   8359 C CE2 . TRP E 5 256 ? 121.995 130.411 77.820  1.00 168.99 ?  256 TRP A CE2 1 
ATOM   8360 C CE3 . TRP E 5 256 ? 124.035 131.142 78.889  1.00 168.99 ?  256 TRP A CE3 1 
ATOM   8361 C CZ2 . TRP E 5 256 ? 122.122 131.368 76.816  1.00 168.99 ?  256 TRP A CZ2 1 
ATOM   8362 C CZ3 . TRP E 5 256 ? 124.159 132.092 77.891  1.00 168.99 ?  256 TRP A CZ3 1 
ATOM   8363 C CH2 . TRP E 5 256 ? 123.208 132.197 76.869  1.00 168.99 ?  256 TRP A CH2 1 
ATOM   8364 N N   . LEU E 5 257 ? 125.262 126.869 79.395  1.00 170.34 ?  257 LEU A N   1 
ATOM   8365 C CA  . LEU E 5 257 ? 125.885 126.368 78.171  1.00 170.34 ?  257 LEU A CA  1 
ATOM   8366 C C   . LEU E 5 257 ? 125.734 124.855 78.055  1.00 170.34 ?  257 LEU A C   1 
ATOM   8367 O O   . LEU E 5 257 ? 125.471 124.329 76.967  1.00 170.34 ?  257 LEU A O   1 
ATOM   8368 C CB  . LEU E 5 257 ? 127.360 126.766 78.132  1.00 170.34 ?  257 LEU A CB  1 
ATOM   8369 C CG  . LEU E 5 257 ? 127.657 128.258 77.974  1.00 170.34 ?  257 LEU A CG  1 
ATOM   8370 C CD1 . LEU E 5 257 ? 129.151 128.521 78.082  1.00 170.34 ?  257 LEU A CD1 1 
ATOM   8371 C CD2 . LEU E 5 257 ? 127.107 128.779 76.654  1.00 170.34 ?  257 LEU A CD2 1 
ATOM   8372 N N   . LEU E 5 258 ? 125.906 124.141 79.170  1.00 173.13 ?  258 LEU A N   1 
ATOM   8373 C CA  . LEU E 5 258 ? 125.712 122.695 79.185  1.00 173.13 ?  258 LEU A CA  1 
ATOM   8374 C C   . LEU E 5 258 ? 124.283 122.323 78.817  1.00 173.13 ?  258 LEU A C   1 
ATOM   8375 O O   . LEU E 5 258 ? 124.054 121.383 78.047  1.00 173.13 ?  258 LEU A O   1 
ATOM   8376 C CB  . LEU E 5 258 ? 126.060 122.148 80.569  1.00 173.13 ?  258 LEU A CB  1 
ATOM   8377 C CG  . LEU E 5 258 ? 125.984 120.640 80.801  1.00 173.13 ?  258 LEU A CG  1 
ATOM   8378 C CD1 . LEU E 5 258 ? 126.970 119.899 79.923  1.00 173.13 ?  258 LEU A CD1 1 
ATOM   8379 C CD2 . LEU E 5 258 ? 126.222 120.337 82.272  1.00 173.13 ?  258 LEU A CD2 1 
ATOM   8380 N N   . HIS E 5 259 ? 123.308 123.048 79.365  1.00 174.15 ?  259 HIS A N   1 
ATOM   8381 C CA  . HIS E 5 259 ? 121.912 122.775 79.042  1.00 174.15 ?  259 HIS A CA  1 
ATOM   8382 C C   . HIS E 5 259 ? 121.630 123.043 77.570  1.00 174.15 ?  259 HIS A C   1 
ATOM   8383 O O   . HIS E 5 259 ? 120.857 122.317 76.935  1.00 174.15 ?  259 HIS A O   1 
ATOM   8384 C CB  . HIS E 5 259 ? 120.993 123.613 79.930  1.00 174.15 ?  259 HIS A CB  1 
ATOM   8385 C CG  . HIS E 5 259 ? 119.565 123.164 79.913  1.00 174.15 ?  259 HIS A CG  1 
ATOM   8386 N ND1 . HIS E 5 259 ? 119.159 121.957 80.440  1.00 174.15 ?  259 HIS A ND1 1 
ATOM   8387 C CD2 . HIS E 5 259 ? 118.448 123.760 79.433  1.00 174.15 ?  259 HIS A CD2 1 
ATOM   8388 C CE1 . HIS E 5 259 ? 117.853 121.829 80.285  1.00 174.15 ?  259 HIS A CE1 1 
ATOM   8389 N NE2 . HIS E 5 259 ? 117.398 122.909 79.677  1.00 174.15 ?  259 HIS A NE2 1 
ATOM   8390 N N   . THR E 5 260 ? 122.250 124.083 77.008  1.00 175.06 ?  260 THR A N   1 
ATOM   8391 C CA  . THR E 5 260 ? 122.052 124.391 75.596  1.00 175.06 ?  260 THR A CA  1 
ATOM   8392 C C   . THR E 5 260 ? 122.935 123.521 74.705  1.00 175.06 ?  260 THR A C   1 
ATOM   8393 O O   . THR E 5 260 ? 122.434 122.768 73.862  1.00 175.06 ?  260 THR A O   1 
ATOM   8394 C CB  . THR E 5 260 ? 122.325 125.875 75.335  1.00 175.06 ?  260 THR A CB  1 
ATOM   8395 O OG1 . THR E 5 260 ? 123.654 126.201 75.761  1.00 175.06 ?  260 THR A OG1 1 
ATOM   8396 C CG2 . THR E 5 260 ? 121.323 126.740 76.084  1.00 175.06 ?  260 THR A CG2 1 
ATOM   8397 N N   . SER E 5 261 ? 124.254 123.606 74.881  1.00 176.74 ?  261 SER A N   1 
ATOM   8398 C CA  . SER E 5 261 ? 125.184 122.902 74.002  1.00 176.74 ?  261 SER A CA  1 
ATOM   8399 C C   . SER E 5 261 ? 125.566 121.529 74.552  1.00 176.74 ?  261 SER A C   1 
ATOM   8400 O O   . SER E 5 261 ? 125.282 120.503 73.927  1.00 176.74 ?  261 SER A O   1 
ATOM   8401 C CB  . SER E 5 261 ? 126.437 123.756 73.778  1.00 176.74 ?  261 SER A CB  1 
ATOM   8402 O OG  . SER E 5 261 ? 126.928 124.273 75.003  1.00 176.74 ?  261 SER A OG  1 
ATOM   8403 N N   . GLY E 5 262 ? 126.200 121.496 75.717  1.00 179.26 ?  262 GLY A N   1 
ATOM   8404 C CA  . GLY E 5 262 ? 126.613 120.255 76.342  1.00 179.26 ?  262 GLY A CA  1 
ATOM   8405 C C   . GLY E 5 262 ? 128.126 120.121 76.407  1.00 179.26 ?  262 GLY A C   1 
ATOM   8406 O O   . GLY E 5 262 ? 128.884 120.997 75.985  1.00 179.26 ?  262 GLY A O   1 
ATOM   8407 N N   . THR E 5 263 ? 128.551 118.982 76.959  1.00 180.98 ?  263 THR A N   1 
ATOM   8408 C CA  . THR E 5 263 ? 129.969 118.678 77.111  1.00 180.98 ?  263 THR A CA  1 
ATOM   8409 C C   . THR E 5 263 ? 130.608 118.206 75.809  1.00 180.98 ?  263 THR A C   1 
ATOM   8410 O O   . THR E 5 263 ? 131.838 118.247 75.684  1.00 180.98 ?  263 THR A O   1 
ATOM   8411 C CB  . THR E 5 263 ? 130.151 117.614 78.204  1.00 180.98 ?  263 THR A CB  1 
ATOM   8412 N N   . GLN E 5 264 ? 129.803 117.801 74.828  1.00 182.44 ?  264 GLN A N   1 
ATOM   8413 C CA  . GLN E 5 264 ? 130.335 117.165 73.630  1.00 182.44 ?  264 GLN A CA  1 
ATOM   8414 C C   . GLN E 5 264 ? 131.271 118.102 72.872  1.00 182.44 ?  264 GLN A C   1 
ATOM   8415 O O   . GLN E 5 264 ? 131.137 119.326 72.925  1.00 182.44 ?  264 GLN A O   1 
ATOM   8416 C CB  . GLN E 5 264 ? 129.194 116.706 72.719  1.00 182.44 ?  264 GLN A CB  1 
ATOM   8417 N N   . ASN E 5 265 ? 132.279 117.490 72.240  1.00 182.70 ?  265 ASN A N   1 
ATOM   8418 C CA  . ASN E 5 265 ? 133.295 118.046 71.340  1.00 182.70 ?  265 ASN A CA  1 
ATOM   8419 C C   . ASN E 5 265 ? 134.317 118.918 72.066  1.00 182.70 ?  265 ASN A C   1 
ATOM   8420 O O   . ASN E 5 265 ? 135.369 119.234 71.501  1.00 182.70 ?  265 ASN A O   1 
ATOM   8421 C CB  . ASN E 5 265 ? 132.651 118.789 70.146  1.00 182.70 ?  265 ASN A CB  1 
ATOM   8422 N N   . CYS E 5 266 ? 134.037 119.251 73.323  1.00 183.33 ?  266 CYS A N   1 
ATOM   8423 C CA  . CYS E 5 266 ? 134.989 119.810 74.289  1.00 183.33 ?  266 CYS A CA  1 
ATOM   8424 C C   . CYS E 5 266 ? 136.020 120.754 73.657  1.00 183.33 ?  266 CYS A C   1 
ATOM   8425 O O   . CYS E 5 266 ? 137.229 120.533 73.730  1.00 183.33 ?  266 CYS A O   1 
ATOM   8426 C CB  . CYS E 5 266 ? 135.691 118.684 75.047  1.00 183.33 ?  266 CYS A CB  1 
ATOM   8427 S SG  . CYS E 5 266 ? 136.608 119.214 76.512  1.00 183.33 ?  266 CYS A SG  1 
ATOM   8428 N N   . GLU E 5 267 ? 135.528 121.820 73.021  1.00 181.82 ?  267 GLU A N   1 
ATOM   8429 C CA  . GLU E 5 267 ? 136.443 122.886 72.615  1.00 181.82 ?  267 GLU A CA  1 
ATOM   8430 C C   . GLU E 5 267 ? 135.937 124.294 72.896  1.00 181.82 ?  267 GLU A C   1 
ATOM   8431 O O   . GLU E 5 267 ? 136.713 125.239 72.722  1.00 181.82 ?  267 GLU A O   1 
ATOM   8432 C CB  . GLU E 5 267 ? 136.795 122.797 71.119  1.00 181.82 ?  267 GLU A CB  1 
ATOM   8433 N N   . VAL E 5 268 ? 134.688 124.478 73.323  1.00 177.47 ?  268 VAL A N   1 
ATOM   8434 C CA  . VAL E 5 268 ? 134.102 125.808 73.446  1.00 177.47 ?  268 VAL A CA  1 
ATOM   8435 C C   . VAL E 5 268 ? 134.162 126.328 74.882  1.00 177.47 ?  268 VAL A C   1 
ATOM   8436 O O   . VAL E 5 268 ? 133.640 127.410 75.170  1.00 177.47 ?  268 VAL A O   1 
ATOM   8437 C CB  . VAL E 5 268 ? 132.660 125.811 72.907  1.00 177.47 ?  268 VAL A CB  1 
ATOM   8438 C CG1 . VAL E 5 268 ? 131.710 125.135 73.889  1.00 177.47 ?  268 VAL A CG1 1 
ATOM   8439 C CG2 . VAL E 5 268 ? 132.199 127.223 72.534  1.00 177.47 ?  268 VAL A CG2 1 
ATOM   8440 N N   . TYR E 5 269 ? 134.810 125.595 75.788  1.00 174.21 ?  269 TYR A N   1 
ATOM   8441 C CA  . TYR E 5 269 ? 134.876 125.970 77.195  1.00 174.21 ?  269 TYR A CA  1 
ATOM   8442 C C   . TYR E 5 269 ? 136.231 126.556 77.583  1.00 174.21 ?  269 TYR A C   1 
ATOM   8443 O O   . TYR E 5 269 ? 136.743 126.262 78.666  1.00 174.21 ?  269 TYR A O   1 
ATOM   8444 C CB  . TYR E 5 269 ? 134.553 124.767 78.081  1.00 174.21 ?  269 TYR A CB  1 
ATOM   8445 C CG  . TYR E 5 269 ? 133.120 124.293 78.005  1.00 174.21 ?  269 TYR A CG  1 
ATOM   8446 C CD1 . TYR E 5 269 ? 132.132 125.084 77.435  1.00 174.21 ?  269 TYR A CD1 1 
ATOM   8447 C CD2 . TYR E 5 269 ? 132.756 123.050 78.505  1.00 174.21 ?  269 TYR A CD2 1 
ATOM   8448 C CE1 . TYR E 5 269 ? 130.821 124.650 77.365  1.00 174.21 ?  269 TYR A CE1 1 
ATOM   8449 C CE2 . TYR E 5 269 ? 131.449 122.607 78.440  1.00 174.21 ?  269 TYR A CE2 1 
ATOM   8450 C CZ  . TYR E 5 269 ? 130.486 123.411 77.869  1.00 174.21 ?  269 TYR A CZ  1 
ATOM   8451 O OH  . TYR E 5 269 ? 129.183 122.974 77.803  1.00 174.21 ?  269 TYR A OH  1 
ATOM   8452 N N   . ARG E 5 270 ? 136.831 127.368 76.713  1.00 172.37 ?  270 ARG A N   1 
ATOM   8453 C CA  . ARG E 5 270 ? 138.139 127.951 77.015  1.00 172.37 ?  270 ARG A CA  1 
ATOM   8454 C C   . ARG E 5 270 ? 138.007 129.149 77.953  1.00 172.37 ?  270 ARG A C   1 
ATOM   8455 O O   . ARG E 5 270 ? 138.480 129.123 79.097  1.00 172.37 ?  270 ARG A O   1 
ATOM   8456 C CB  . ARG E 5 270 ? 138.829 128.363 75.710  1.00 172.37 ?  270 ARG A CB  1 
ATOM   8457 N N   . SER E 5 271 ? 137.338 130.203 77.478  1.00 170.48 ?  271 SER A N   1 
ATOM   8458 C CA  . SER E 5 271 ? 137.243 131.440 78.243  1.00 170.48 ?  271 SER A CA  1 
ATOM   8459 C C   . SER E 5 271 ? 136.429 131.258 79.514  1.00 170.48 ?  271 SER A C   1 
ATOM   8460 O O   . SER E 5 271 ? 136.777 131.827 80.553  1.00 170.48 ?  271 SER A O   1 
ATOM   8461 C CB  . SER E 5 271 ? 136.636 132.547 77.381  1.00 170.48 ?  271 SER A CB  1 
ATOM   8462 O OG  . SER E 5 271 ? 135.434 132.114 76.769  1.00 170.48 ?  271 SER A OG  1 
ATOM   8463 N N   . VAL E 5 272 ? 135.350 130.475 79.457  1.00 167.58 ?  272 VAL A N   1 
ATOM   8464 C CA  . VAL E 5 272 ? 134.512 130.288 80.636  1.00 167.58 ?  272 VAL A CA  1 
ATOM   8465 C C   . VAL E 5 272 ? 135.269 129.528 81.722  1.00 167.58 ?  272 VAL A C   1 
ATOM   8466 O O   . VAL E 5 272 ? 135.140 129.833 82.912  1.00 167.58 ?  272 VAL A O   1 
ATOM   8467 C CB  . VAL E 5 272 ? 133.192 129.593 80.251  1.00 167.58 ?  272 VAL A CB  1 
ATOM   8468 C CG1 . VAL E 5 272 ? 132.405 130.459 79.280  1.00 167.58 ?  272 VAL A CG1 1 
ATOM   8469 C CG2 . VAL E 5 272 ? 133.454 128.228 79.642  1.00 167.58 ?  272 VAL A CG2 1 
ATOM   8470 N N   . ASP E 5 273 ? 136.090 128.549 81.335  1.00 166.22 ?  273 ASP A N   1 
ATOM   8471 C CA  . ASP E 5 273 ? 136.854 127.792 82.323  1.00 166.22 ?  273 ASP A CA  1 
ATOM   8472 C C   . ASP E 5 273 ? 137.983 128.645 82.898  1.00 166.22 ?  273 ASP A C   1 
ATOM   8473 O O   . ASP E 5 273 ? 138.253 128.595 84.108  1.00 166.22 ?  273 ASP A O   1 
ATOM   8474 C CB  . ASP E 5 273 ? 137.377 126.502 81.675  1.00 166.22 ?  273 ASP A CB  1 
ATOM   8475 C CG  . ASP E 5 273 ? 138.168 125.608 82.629  1.00 166.22 ?  273 ASP A CG  1 
ATOM   8476 O OD1 . ASP E 5 273 ? 138.926 126.102 83.484  1.00 166.22 ?  273 ASP A OD1 1 
ATOM   8477 O OD2 . ASP E 5 273 ? 138.040 124.372 82.497  1.00 166.22 -1 273 ASP A OD2 1 
ATOM   8478 N N   . LEU E 5 274 ? 138.636 129.451 82.055  1.00 165.54 ?  274 LEU A N   1 
ATOM   8479 C CA  . LEU E 5 274 ? 139.637 130.384 82.568  1.00 165.54 ?  274 LEU A CA  1 
ATOM   8480 C C   . LEU E 5 274 ? 139.010 131.370 83.547  1.00 165.54 ?  274 LEU A C   1 
ATOM   8481 O O   . LEU E 5 274 ? 139.594 131.686 84.594  1.00 165.54 ?  274 LEU A O   1 
ATOM   8482 C CB  . LEU E 5 274 ? 140.308 131.124 81.410  1.00 165.54 ?  274 LEU A CB  1 
ATOM   8483 C CG  . LEU E 5 274 ? 141.616 130.537 80.874  1.00 165.54 ?  274 LEU A CG  1 
ATOM   8484 C CD1 . LEU E 5 274 ? 142.704 130.639 81.927  1.00 165.54 ?  274 LEU A CD1 1 
ATOM   8485 C CD2 . LEU E 5 274 ? 141.437 129.094 80.428  1.00 165.54 ?  274 LEU A CD2 1 
ATOM   8486 N N   . ALA E 5 275 ? 137.811 131.861 83.222  1.00 159.71 ?  275 ALA A N   1 
ATOM   8487 C CA  . ALA E 5 275 ? 137.088 132.740 84.131  1.00 159.71 ?  275 ALA A CA  1 
ATOM   8488 C C   . ALA E 5 275 ? 136.752 132.026 85.432  1.00 159.71 ?  275 ALA A C   1 
ATOM   8489 O O   . ALA E 5 275 ? 136.836 132.618 86.510  1.00 159.71 ?  275 ALA A O   1 
ATOM   8490 C CB  . ALA E 5 275 ? 135.819 133.262 83.458  1.00 159.71 ?  275 ALA A CB  1 
ATOM   8491 N N   . PHE E 5 276 ? 136.361 130.754 85.352  1.00 156.58 ?  276 PHE A N   1 
ATOM   8492 C CA  . PHE E 5 276 ? 136.071 129.997 86.564  1.00 156.58 ?  276 PHE A CA  1 
ATOM   8493 C C   . PHE E 5 276 ? 137.296 129.910 87.463  1.00 156.58 ?  276 PHE A C   1 
ATOM   8494 O O   . PHE E 5 276 ? 137.205 130.110 88.681  1.00 156.58 ?  276 PHE A O   1 
ATOM   8495 C CB  . PHE E 5 276 ? 135.567 128.601 86.203  1.00 156.58 ?  276 PHE A CB  1 
ATOM   8496 C CG  . PHE E 5 276 ? 135.239 127.763 87.407  1.00 156.58 ?  276 PHE A CG  1 
ATOM   8497 C CD1 . PHE E 5 276 ? 134.040 127.991 88.093  1.00 156.58 ?  276 PHE A CD1 1 
ATOM   8498 C CD2 . PHE E 5 276 ? 136.160 126.814 87.886  1.00 156.58 ?  276 PHE A CD2 1 
ATOM   8499 C CE1 . PHE E 5 276 ? 133.737 127.246 89.236  1.00 156.58 ?  276 PHE A CE1 1 
ATOM   8500 C CE2 . PHE E 5 276 ? 135.883 126.115 89.072  1.00 156.58 ?  276 PHE A CE2 1 
ATOM   8501 C CZ  . PHE E 5 276 ? 134.664 126.324 89.744  1.00 156.58 ?  276 PHE A CZ  1 
ATOM   8502 N N   . PHE E 5 277 ? 138.459 129.618 86.877  1.00 157.92 ?  277 PHE A N   1 
ATOM   8503 C CA  . PHE E 5 277 ? 139.680 129.544 87.682  1.00 157.92 ?  277 PHE A CA  1 
ATOM   8504 C C   . PHE E 5 277 ? 140.035 130.900 88.293  1.00 157.92 ?  277 PHE A C   1 
ATOM   8505 O O   . PHE E 5 277 ? 140.404 130.959 89.469  1.00 157.92 ?  277 PHE A O   1 
ATOM   8506 C CB  . PHE E 5 277 ? 140.850 128.996 86.855  1.00 157.92 ?  277 PHE A CB  1 
ATOM   8507 C CG  . PHE E 5 277 ? 140.824 127.510 86.516  1.00 157.92 ?  277 PHE A CG  1 
ATOM   8508 C CD1 . PHE E 5 277 ? 140.180 126.561 87.345  1.00 157.92 ?  277 PHE A CD1 1 
ATOM   8509 C CD2 . PHE E 5 277 ? 141.500 127.064 85.364  1.00 157.92 ?  277 PHE A CD2 1 
ATOM   8510 C CE1 . PHE E 5 277 ? 140.172 125.198 86.995  1.00 157.92 ?  277 PHE A CE1 1 
ATOM   8511 C CE2 . PHE E 5 277 ? 141.512 125.699 85.029  1.00 157.92 ?  277 PHE A CE2 1 
ATOM   8512 C CZ  . PHE E 5 277 ? 140.834 124.769 85.832  1.00 157.92 ?  277 PHE A CZ  1 
ATOM   8513 N N   . ILE E 5 278 ? 139.923 131.985 87.522  1.00 154.66 ?  278 ILE A N   1 
ATOM   8514 C CA  . ILE E 5 278 ? 140.295 133.277 88.098  1.00 154.66 ?  278 ILE A CA  1 
ATOM   8515 C C   . ILE E 5 278 ? 139.305 133.691 89.187  1.00 154.66 ?  278 ILE A C   1 
ATOM   8516 O O   . ILE E 5 278 ? 139.698 134.299 90.189  1.00 154.66 ?  278 ILE A O   1 
ATOM   8517 C CB  . ILE E 5 278 ? 140.446 134.363 87.014  1.00 154.66 ?  278 ILE A CB  1 
ATOM   8518 C CG1 . ILE E 5 278 ? 139.134 134.612 86.277  1.00 154.66 ?  278 ILE A CG1 1 
ATOM   8519 C CG2 . ILE E 5 278 ? 141.543 133.980 86.030  1.00 154.66 ?  278 ILE A CG2 1 
ATOM   8520 C CD1 . ILE E 5 278 ? 139.167 135.822 85.367  1.00 154.66 ?  278 ILE A CD1 1 
ATOM   8521 N N   . THR E 5 279 ? 138.020 133.362 89.034  1.00 150.17 ?  279 THR A N   1 
ATOM   8522 C CA  . THR E 5 279 ? 137.060 133.666 90.093  1.00 150.17 ?  279 THR A CA  1 
ATOM   8523 C C   . THR E 5 279 ? 137.316 132.822 91.336  1.00 150.17 ?  279 THR A C   1 
ATOM   8524 O O   . THR E 5 279 ? 137.149 133.302 92.464  1.00 150.17 ?  279 THR A O   1 
ATOM   8525 C CB  . THR E 5 279 ? 135.631 133.466 89.591  1.00 150.17 ?  279 THR A CB  1 
ATOM   8526 O OG1 . THR E 5 279 ? 135.441 132.100 89.204  1.00 150.17 ?  279 THR A OG1 1 
ATOM   8527 C CG2 . THR E 5 279 ? 135.339 134.387 88.418  1.00 150.17 ?  279 THR A CG2 1 
ATOM   8528 N N   . LEU E 5 280 ? 137.729 131.558 91.173  1.00 148.47 ?  280 LEU A N   1 
ATOM   8529 C CA  . LEU E 5 280 ? 138.155 130.729 92.311  1.00 148.47 ?  280 LEU A CA  1 
ATOM   8530 C C   . LEU E 5 280 ? 139.394 131.327 92.995  1.00 148.47 ?  280 LEU A C   1 
ATOM   8531 O O   . LEU E 5 280 ? 139.405 131.433 94.215  1.00 148.47 ?  280 LEU A O   1 
ATOM   8532 C CB  . LEU E 5 280 ? 138.342 129.258 91.885  1.00 148.47 ?  280 LEU A CB  1 
ATOM   8533 C CG  . LEU E 5 280 ? 137.155 128.329 92.225  1.00 148.47 ?  280 LEU A CG  1 
ATOM   8534 C CD1 . LEU E 5 280 ? 137.041 128.069 93.731  1.00 148.47 ?  280 LEU A CD1 1 
ATOM   8535 C CD2 . LEU E 5 280 ? 135.805 128.853 91.728  1.00 148.47 ?  280 LEU A CD2 1 
ATOM   8536 N N   . SER E 5 281 ? 140.289 131.967 92.238  1.00 149.16 ?  281 SER A N   1 
ATOM   8537 C CA  . SER E 5 281 ? 141.327 132.835 92.811  1.00 149.16 ?  281 SER A CA  1 
ATOM   8538 C C   . SER E 5 281 ? 140.764 134.013 93.616  1.00 149.16 ?  281 SER A C   1 
ATOM   8539 O O   . SER E 5 281 ? 141.229 134.266 94.734  1.00 149.16 ?  281 SER A O   1 
ATOM   8540 C CB  . SER E 5 281 ? 142.257 133.353 91.718  1.00 149.16 ?  281 SER A CB  1 
ATOM   8541 O OG  . SER E 5 281 ? 141.731 134.498 91.071  1.00 149.16 ?  281 SER A OG  1 
ATOM   8542 N N   . PHE E 5 282 ? 139.784 134.742 93.070  1.00 146.85 ?  282 PHE A N   1 
ATOM   8543 C CA  . PHE E 5 282 ? 139.162 135.826 93.832  1.00 146.85 ?  282 PHE A CA  1 
ATOM   8544 C C   . PHE E 5 282 ? 138.492 135.311 95.100  1.00 146.85 ?  282 PHE A C   1 
ATOM   8545 O O   . PHE E 5 282 ? 138.310 136.071 96.057  1.00 146.85 ?  282 PHE A O   1 
ATOM   8546 C CB  . PHE E 5 282 ? 138.129 136.593 92.998  1.00 146.85 ?  282 PHE A CB  1 
ATOM   8547 C CG  . PHE E 5 282 ? 138.710 137.379 91.856  1.00 146.85 ?  282 PHE A CG  1 
ATOM   8548 C CD1 . PHE E 5 282 ? 139.289 138.617 92.079  1.00 146.85 ?  282 PHE A CD1 1 
ATOM   8549 C CD2 . PHE E 5 282 ? 138.604 136.926 90.555  1.00 146.85 ?  282 PHE A CD2 1 
ATOM   8550 C CE1 . PHE E 5 282 ? 139.808 139.356 91.033  1.00 146.85 ?  282 PHE A CE1 1 
ATOM   8551 C CE2 . PHE E 5 282 ? 139.120 137.659 89.503  1.00 146.85 ?  282 PHE A CE2 1 
ATOM   8552 C CZ  . PHE E 5 282 ? 139.720 138.878 89.742  1.00 146.85 ?  282 PHE A CZ  1 
ATOM   8553 N N   . THR E 5 283 ? 138.099 134.036 95.114  1.00 141.46 ?  283 THR A N   1 
ATOM   8554 C CA  . THR E 5 283 ? 137.384 133.463 96.268  1.00 141.46 ?  283 THR A CA  1 
ATOM   8555 C C   . THR E 5 283 ? 138.230 133.520 97.550  1.00 141.46 ?  283 THR A C   1 
ATOM   8556 O O   . THR E 5 283 ? 137.744 133.878 98.625  1.00 141.46 ?  283 THR A O   1 
ATOM   8557 C CB  . THR E 5 283 ? 136.875 132.046 95.971  1.00 141.46 ?  283 THR A CB  1 
ATOM   8558 O OG1 . THR E 5 283 ? 136.042 132.049 94.827  1.00 141.46 ?  283 THR A OG1 1 
ATOM   8559 C CG2 . THR E 5 283 ? 136.010 131.495 97.095  1.00 141.46 ?  283 THR A CG2 1 
ATOM   8560 N N   . TYR E 5 284 ? 139.546 133.339 97.448  1.00 144.48 ?  284 TYR A N   1 
ATOM   8561 C CA  . TYR E 5 284 ? 140.415 133.455 98.623  1.00 144.48 ?  284 TYR A CA  1 
ATOM   8562 C C   . TYR E 5 284 ? 140.482 134.884 99.165  1.00 144.48 ?  284 TYR A C   1 
ATOM   8563 O O   . TYR E 5 284 ? 140.806 135.049 100.337 1.00 144.48 ?  284 TYR A O   1 
ATOM   8564 C CB  . TYR E 5 284 ? 141.803 132.879 98.307  1.00 144.48 ?  284 TYR A CB  1 
ATOM   8565 C CG  . TYR E 5 284 ? 141.707 131.554 97.576  1.00 144.48 ?  284 TYR A CG  1 
ATOM   8566 C CD1 . TYR E 5 284 ? 140.845 130.552 98.071  1.00 144.48 ?  284 TYR A CD1 1 
ATOM   8567 C CD2 . TYR E 5 284 ? 142.317 131.405 96.316  1.00 144.48 ?  284 TYR A CD2 1 
ATOM   8568 C CE1 . TYR E 5 284 ? 140.529 129.442 97.273  1.00 144.48 ?  284 TYR A CE1 1 
ATOM   8569 C CE2 . TYR E 5 284 ? 142.019 130.281 95.525  1.00 144.48 ?  284 TYR A CE2 1 
ATOM   8570 C CZ  . TYR E 5 284 ? 141.089 129.327 95.985  1.00 144.48 ?  284 TYR A CZ  1 
ATOM   8571 O OH  . TYR E 5 284 ? 140.705 128.316 95.175  1.00 144.48 ?  284 TYR A OH  1 
ATOM   8572 N N   . MET E 5 285 ? 140.174 135.887 98.354  1.00 143.70 ?  285 MET A N   1 
ATOM   8573 C CA  . MET E 5 285 ? 140.263 137.256 98.848  1.00 143.70 ?  285 MET A CA  1 
ATOM   8574 C C   . MET E 5 285 ? 139.446 137.444 100.118 1.00 143.70 ?  285 MET A C   1 
ATOM   8575 O O   . MET E 5 285 ? 139.787 138.291 100.949 1.00 143.70 ?  285 MET A O   1 
ATOM   8576 C CB  . MET E 5 285 ? 139.808 138.245 97.776  1.00 143.70 ?  285 MET A CB  1 
ATOM   8577 C CG  . MET E 5 285 ? 140.718 138.310 96.564  1.00 143.70 ?  285 MET A CG  1 
ATOM   8578 S SD  . MET E 5 285 ? 140.085 139.430 95.304  1.00 143.70 ?  285 MET A SD  1 
ATOM   8579 C CE  . MET E 5 285 ? 140.337 141.014 96.102  1.00 143.70 ?  285 MET A CE  1 
ATOM   8580 N N   . ASN E 5 286 ? 138.371 136.672 100.291 1.00 137.56 ?  286 ASN A N   1 
ATOM   8581 C CA  . ASN E 5 286 ? 137.610 136.742 101.534 1.00 137.56 ?  286 ASN A CA  1 
ATOM   8582 C C   . ASN E 5 286 ? 138.467 136.314 102.719 1.00 137.56 ?  286 ASN A C   1 
ATOM   8583 O O   . ASN E 5 286 ? 138.493 136.984 103.757 1.00 137.56 ?  286 ASN A O   1 
ATOM   8584 C CB  . ASN E 5 286 ? 136.356 135.872 101.432 1.00 137.56 ?  286 ASN A CB  1 
ATOM   8585 C CG  . ASN E 5 286 ? 135.413 136.061 102.609 1.00 137.56 ?  286 ASN A CG  1 
ATOM   8586 O OD1 . ASN E 5 286 ? 134.343 135.456 102.672 1.00 137.56 ?  286 ASN A OD1 1 
ATOM   8587 N ND2 . ASN E 5 286 ? 135.806 136.913 103.545 1.00 137.56 ?  286 ASN A ND2 1 
ATOM   8588 N N   . SER E 5 287 ? 139.185 135.197 102.575 1.00 139.30 ?  287 SER A N   1 
ATOM   8589 C CA  . SER E 5 287 ? 140.074 134.750 103.642 1.00 139.30 ?  287 SER A CA  1 
ATOM   8590 C C   . SER E 5 287 ? 141.212 135.738 103.855 1.00 139.30 ?  287 SER A C   1 
ATOM   8591 O O   . SER E 5 287 ? 141.660 135.948 104.988 1.00 139.30 ?  287 SER A O   1 
ATOM   8592 C CB  . SER E 5 287 ? 140.620 133.359 103.323 1.00 139.30 ?  287 SER A CB  1 
ATOM   8593 O OG  . SER E 5 287 ? 139.580 132.398 103.290 1.00 139.30 ?  287 SER A OG  1 
ATOM   8594 N N   . MET E 5 288 ? 141.701 136.347 102.772 1.00 143.63 ?  288 MET A N   1 
ATOM   8595 C CA  . MET E 5 288 ? 142.761 137.343 102.905 1.00 143.63 ?  288 MET A CA  1 
ATOM   8596 C C   . MET E 5 288 ? 142.287 138.566 103.683 1.00 143.63 ?  288 MET A C   1 
ATOM   8597 O O   . MET E 5 288 ? 143.001 139.069 104.559 1.00 143.63 ?  288 MET A O   1 
ATOM   8598 C CB  . MET E 5 288 ? 143.270 137.759 101.525 1.00 143.63 ?  288 MET A CB  1 
ATOM   8599 C CG  . MET E 5 288 ? 144.415 138.760 101.576 1.00 143.63 ?  288 MET A CG  1 
ATOM   8600 S SD  . MET E 5 288 ? 145.029 139.230 99.949  1.00 143.63 ?  288 MET A SD  1 
ATOM   8601 C CE  . MET E 5 288 ? 143.678 140.245 99.357  1.00 143.63 ?  288 MET A CE  1 
ATOM   8602 N N   . LEU E 5 289 ? 141.086 139.056 103.381 1.00 136.78 ?  289 LEU A N   1 
ATOM   8603 C CA  . LEU E 5 289 ? 140.581 140.303 103.937 1.00 136.78 ?  289 LEU A CA  1 
ATOM   8604 C C   . LEU E 5 289 ? 139.823 140.125 105.245 1.00 136.78 ?  289 LEU A C   1 
ATOM   8605 O O   . LEU E 5 289 ? 139.456 141.128 105.865 1.00 136.78 ?  289 LEU A O   1 
ATOM   8606 C CB  . LEU E 5 289 ? 139.668 140.998 102.921 1.00 136.78 ?  289 LEU A CB  1 
ATOM   8607 C CG  . LEU E 5 289 ? 140.330 141.496 101.636 1.00 136.78 ?  289 LEU A CG  1 
ATOM   8608 C CD1 . LEU E 5 289 ? 139.286 142.033 100.670 1.00 136.78 ?  289 LEU A CD1 1 
ATOM   8609 C CD2 . LEU E 5 289 ? 141.377 142.555 101.943 1.00 136.78 ?  289 LEU A CD2 1 
ATOM   8610 N N   . ASP E 5 290 ? 139.569 138.889 105.672 1.00 134.14 ?  290 ASP A N   1 
ATOM   8611 C CA  . ASP E 5 290 ? 138.853 138.680 106.928 1.00 134.14 ?  290 ASP A CA  1 
ATOM   8612 C C   . ASP E 5 290 ? 139.500 139.369 108.127 1.00 134.14 ?  290 ASP A C   1 
ATOM   8613 O O   . ASP E 5 290 ? 138.756 139.953 108.934 1.00 134.14 ?  290 ASP A O   1 
ATOM   8614 C CB  . ASP E 5 290 ? 138.691 137.176 107.188 1.00 134.14 ?  290 ASP A CB  1 
ATOM   8615 C CG  . ASP E 5 290 ? 137.418 136.615 106.584 1.00 134.14 ?  290 ASP A CG  1 
ATOM   8616 O OD1 . ASP E 5 290 ? 136.434 137.373 106.457 1.00 134.14 ?  290 ASP A OD1 1 
ATOM   8617 O OD2 . ASP E 5 290 ? 137.401 135.416 106.237 1.00 134.14 -1 290 ASP A OD2 1 
ATOM   8618 N N   . PRO E 5 291 ? 140.826 139.336 108.325 1.00 135.62 ?  291 PRO A N   1 
ATOM   8619 C CA  . PRO E 5 291 ? 141.392 140.053 109.483 1.00 135.62 ?  291 PRO A CA  1 
ATOM   8620 C C   . PRO E 5 291 ? 141.104 141.545 109.492 1.00 135.62 ?  291 PRO A C   1 
ATOM   8621 O O   . PRO E 5 291 ? 140.842 142.110 110.561 1.00 135.62 ?  291 PRO A O   1 
ATOM   8622 C CB  . PRO E 5 291 ? 142.895 139.769 109.365 1.00 135.62 ?  291 PRO A CB  1 
ATOM   8623 C CG  . PRO E 5 291 ? 142.978 138.501 108.618 1.00 135.62 ?  291 PRO A CG  1 
ATOM   8624 C CD  . PRO E 5 291 ? 141.860 138.550 107.626 1.00 135.62 ?  291 PRO A CD  1 
ATOM   8625 N N   . VAL E 5 292 ? 141.135 142.202 108.331 1.00 132.64 ?  292 VAL A N   1 
ATOM   8626 C CA  . VAL E 5 292 ? 140.996 143.655 108.311 1.00 132.64 ?  292 VAL A CA  1 
ATOM   8627 C C   . VAL E 5 292 ? 139.539 144.098 108.368 1.00 132.64 ?  292 VAL A C   1 
ATOM   8628 O O   . VAL E 5 292 ? 139.260 145.227 108.788 1.00 132.64 ?  292 VAL A O   1 
ATOM   8629 C CB  . VAL E 5 292 ? 141.695 144.247 107.073 1.00 132.64 ?  292 VAL A CB  1 
ATOM   8630 C CG1 . VAL E 5 292 ? 140.887 143.986 105.811 1.00 132.64 ?  292 VAL A CG1 1 
ATOM   8631 C CG2 . VAL E 5 292 ? 141.956 145.737 107.259 1.00 132.64 ?  292 VAL A CG2 1 
ATOM   8632 N N   . VAL E 5 293 ? 138.599 143.241 107.975 1.00 126.37 ?  293 VAL A N   1 
ATOM   8633 C CA  . VAL E 5 293 ? 137.192 143.625 107.994 1.00 126.37 ?  293 VAL A CA  1 
ATOM   8634 C C   . VAL E 5 293 ? 136.503 143.207 109.292 1.00 126.37 ?  293 VAL A C   1 
ATOM   8635 O O   . VAL E 5 293 ? 135.524 143.839 109.703 1.00 126.37 ?  293 VAL A O   1 
ATOM   8636 C CB  . VAL E 5 293 ? 136.469 143.040 106.768 1.00 126.37 ?  293 VAL A CB  1 
ATOM   8637 C CG1 . VAL E 5 293 ? 135.056 143.581 106.669 1.00 126.37 ?  293 VAL A CG1 1 
ATOM   8638 C CG2 . VAL E 5 293 ? 137.235 143.365 105.499 1.00 126.37 ?  293 VAL A CG2 1 
ATOM   8639 N N   . TYR E 5 294 ? 137.054 142.216 109.965 1.00 122.19 ?  294 TYR A N   1 
ATOM   8640 C CA  . TYR E 5 294 ? 136.424 141.716 111.165 1.00 122.19 ?  294 TYR A CA  1 
ATOM   8641 C C   . TYR E 5 294 ? 137.214 141.963 112.410 1.00 122.19 ?  294 TYR A C   1 
ATOM   8642 O O   . TYR E 5 294 ? 136.727 142.595 113.340 1.00 122.19 ?  294 TYR A O   1 
ATOM   8643 C CB  . TYR E 5 294 ? 136.248 140.218 111.027 1.00 122.19 ?  294 TYR A CB  1 
ATOM   8644 C CG  . TYR E 5 294 ? 134.898 139.886 110.524 1.00 122.19 ?  294 TYR A CG  1 
ATOM   8645 C CD1 . TYR E 5 294 ? 134.558 140.131 109.208 1.00 122.19 ?  294 TYR A CD1 1 
ATOM   8646 C CD2 . TYR E 5 294 ? 133.943 139.380 111.373 1.00 122.19 ?  294 TYR A CD2 1 
ATOM   8647 C CE1 . TYR E 5 294 ? 133.300 139.847 108.746 1.00 122.19 ?  294 TYR A CE1 1 
ATOM   8648 C CE2 . TYR E 5 294 ? 132.688 139.091 110.925 1.00 122.19 ?  294 TYR A CE2 1 
ATOM   8649 C CZ  . TYR E 5 294 ? 132.379 139.331 109.615 1.00 122.19 ?  294 TYR A CZ  1 
ATOM   8650 O OH  . TYR E 5 294 ? 131.130 139.053 109.190 1.00 122.19 ?  294 TYR A OH  1 
ATOM   8651 N N   . TYR E 5 295 ? 138.433 141.459 112.449 1.00 131.03 ?  295 TYR A N   1 
ATOM   8652 C CA  . TYR E 5 295 ? 139.224 141.561 113.669 1.00 131.03 ?  295 TYR A CA  1 
ATOM   8653 C C   . TYR E 5 295 ? 139.922 142.910 113.798 1.00 131.03 ?  295 TYR A C   1 
ATOM   8654 O O   . TYR E 5 295 ? 139.759 143.597 114.810 1.00 131.03 ?  295 TYR A O   1 
ATOM   8655 C CB  . TYR E 5 295 ? 140.245 140.421 113.727 1.00 131.03 ?  295 TYR A CB  1 
ATOM   8656 C CG  . TYR E 5 295 ? 139.665 139.076 113.363 1.00 131.03 ?  295 TYR A CG  1 
ATOM   8657 C CD1 . TYR E 5 295 ? 138.845 138.394 114.248 1.00 131.03 ?  295 TYR A CD1 1 
ATOM   8658 C CD2 . TYR E 5 295 ? 139.926 138.494 112.133 1.00 131.03 ?  295 TYR A CD2 1 
ATOM   8659 C CE1 . TYR E 5 295 ? 138.310 137.168 113.922 1.00 131.03 ?  295 TYR A CE1 1 
ATOM   8660 C CE2 . TYR E 5 295 ? 139.393 137.268 111.796 1.00 131.03 ?  295 TYR A CE2 1 
ATOM   8661 C CZ  . TYR E 5 295 ? 138.585 136.609 112.695 1.00 131.03 ?  295 TYR A CZ  1 
ATOM   8662 O OH  . TYR E 5 295 ? 138.049 135.387 112.367 1.00 131.03 ?  295 TYR A OH  1 
ATOM   8663 N N   . PHE E 5 296 ? 140.700 143.305 112.788 1.00 134.04 ?  296 PHE A N   1 
ATOM   8664 C CA  . PHE E 5 296 ? 141.445 144.556 112.885 1.00 134.04 ?  296 PHE A CA  1 
ATOM   8665 C C   . PHE E 5 296 ? 140.516 145.763 112.910 1.00 134.04 ?  296 PHE A C   1 
ATOM   8666 O O   . PHE E 5 296 ? 140.866 146.802 113.480 1.00 134.04 ?  296 PHE A O   1 
ATOM   8667 C CB  . PHE E 5 296 ? 142.444 144.664 111.731 1.00 134.04 ?  296 PHE A CB  1 
ATOM   8668 C CG  . PHE E 5 296 ? 143.483 143.574 111.725 1.00 134.04 ?  296 PHE A CG  1 
ATOM   8669 C CD1 . PHE E 5 296 ? 143.744 142.841 112.872 1.00 134.04 ?  296 PHE A CD1 1 
ATOM   8670 C CD2 . PHE E 5 296 ? 144.198 143.282 110.574 1.00 134.04 ?  296 PHE A CD2 1 
ATOM   8671 C CE1 . PHE E 5 296 ? 144.694 141.838 112.874 1.00 134.04 ?  296 PHE A CE1 1 
ATOM   8672 C CE2 . PHE E 5 296 ? 145.154 142.279 110.570 1.00 134.04 ?  296 PHE A CE2 1 
ATOM   8673 C CZ  . PHE E 5 296 ? 145.400 141.556 111.724 1.00 134.04 ?  296 PHE A CZ  1 
ATOM   8674 N N   . SER E 5 297 ? 139.330 145.642 112.312 1.00 127.70 ?  297 SER A N   1 
ATOM   8675 C CA  . SER E 5 297 ? 138.375 146.741 112.310 1.00 127.70 ?  297 SER A CA  1 
ATOM   8676 C C   . SER E 5 297 ? 137.715 146.948 113.668 1.00 127.70 ?  297 SER A C   1 
ATOM   8677 O O   . SER E 5 297 ? 137.148 148.018 113.909 1.00 127.70 ?  297 SER A O   1 
ATOM   8678 C CB  . SER E 5 297 ? 137.310 146.496 111.240 1.00 127.70 ?  297 SER A CB  1 
ATOM   8679 O OG  . SER E 5 297 ? 137.868 146.557 109.939 1.00 127.70 ?  297 SER A OG  1 
ATOM   8680 N N   . SER E 5 298 ? 137.777 145.961 114.556 1.00 127.36 ?  298 SER A N   1 
ATOM   8681 C CA  . SER E 5 298 ? 137.145 146.096 115.865 1.00 127.36 ?  298 SER A CA  1 
ATOM   8682 C C   . SER E 5 298 ? 137.945 147.058 116.736 1.00 127.36 ?  298 SER A C   1 
ATOM   8683 O O   . SER E 5 298 ? 139.154 146.867 116.909 1.00 127.36 ?  298 SER A O   1 
ATOM   8684 C CB  . SER E 5 298 ? 137.032 144.735 116.548 1.00 127.36 ?  298 SER A CB  1 
ATOM   8685 O OG  . SER E 5 298 ? 136.525 144.864 117.866 1.00 127.36 ?  298 SER A OG  1 
ATOM   8686 N N   . PRO E 5 299 ? 137.319 148.104 117.284 1.00 127.97 ?  299 PRO A N   1 
ATOM   8687 C CA  . PRO E 5 299 ? 138.066 149.020 118.164 1.00 127.97 ?  299 PRO A CA  1 
ATOM   8688 C C   . PRO E 5 299 ? 138.661 148.339 119.384 1.00 127.97 ?  299 PRO A C   1 
ATOM   8689 O O   . PRO E 5 299 ? 139.770 148.690 119.806 1.00 127.97 ?  299 PRO A O   1 
ATOM   8690 C CB  . PRO E 5 299 ? 137.010 150.067 118.552 1.00 127.97 ?  299 PRO A CB  1 
ATOM   8691 C CG  . PRO E 5 299 ? 135.692 149.404 118.293 1.00 127.97 ?  299 PRO A CG  1 
ATOM   8692 C CD  . PRO E 5 299 ? 135.920 148.522 117.110 1.00 127.97 ?  299 PRO A CD  1 
ATOM   8693 N N   . SER E 5 300 ? 137.951 147.374 119.968 1.00 131.26 ?  300 SER A N   1 
ATOM   8694 C CA  . SER E 5 300 ? 138.461 146.640 121.120 1.00 131.26 ?  300 SER A CA  1 
ATOM   8695 C C   . SER E 5 300 ? 139.685 145.818 120.736 1.00 131.26 ?  300 SER A C   1 
ATOM   8696 O O   . SER E 5 300 ? 140.668 145.765 121.482 1.00 131.26 ?  300 SER A O   1 
ATOM   8697 C CB  . SER E 5 300 ? 137.373 145.736 121.704 1.00 131.26 ?  300 SER A CB  1 
ATOM   8698 O OG  . SER E 5 300 ? 137.880 144.958 122.774 1.00 131.26 ?  300 SER A OG  1 
ATOM   8699 N N   . PHE E 5 301 ? 139.629 145.179 119.574 1.00 135.55 ?  301 PHE A N   1 
ATOM   8700 C CA  . PHE E 5 301 ? 140.729 144.360 119.080 1.00 135.55 ?  301 PHE A CA  1 
ATOM   8701 C C   . PHE E 5 301 ? 141.909 145.234 118.667 1.00 135.55 ?  301 PHE A C   1 
ATOM   8702 O O   . PHE E 5 301 ? 141.728 146.335 118.147 1.00 135.55 ?  301 PHE A O   1 
ATOM   8703 C CB  . PHE E 5 301 ? 140.253 143.501 117.906 1.00 135.55 ?  301 PHE A CB  1 
ATOM   8704 C CG  . PHE E 5 301 ? 141.235 142.447 117.475 1.00 135.55 ?  301 PHE A CG  1 
ATOM   8705 C CD1 . PHE E 5 301 ? 142.279 142.758 116.618 1.00 135.55 ?  301 PHE A CD1 1 
ATOM   8706 C CD2 . PHE E 5 301 ? 141.092 141.138 117.900 1.00 135.55 ?  301 PHE A CD2 1 
ATOM   8707 C CE1 . PHE E 5 301 ? 143.174 141.788 116.214 1.00 135.55 ?  301 PHE A CE1 1 
ATOM   8708 C CE2 . PHE E 5 301 ? 141.983 140.163 117.500 1.00 135.55 ?  301 PHE A CE2 1 
ATOM   8709 C CZ  . PHE E 5 301 ? 143.026 140.488 116.655 1.00 135.55 ?  301 PHE A CZ  1 
HETATM 8710 C C01 . CW3 F 6 .   ? 145.282 121.449 92.940  1.00 152.87 ?  401 CW3 A C01 1 
HETATM 8711 C C02 . CW3 F 6 .   ? 143.870 122.045 92.844  1.00 152.87 ?  401 CW3 A C02 1 
HETATM 8712 C C03 . CW3 F 6 .   ? 143.781 123.221 91.872  1.00 152.87 ?  401 CW3 A C03 1 
HETATM 8713 N N04 . CW3 F 6 .   ? 142.350 123.504 91.687  1.00 152.87 ?  401 CW3 A N04 1 
HETATM 8714 C C05 . CW3 F 6 .   ? 141.578 123.953 92.777  1.00 152.87 ?  401 CW3 A C05 1 
HETATM 8715 C C06 . CW3 F 6 .   ? 142.055 124.961 93.619  1.00 152.87 ?  401 CW3 A C06 1 
HETATM 8716 C C07 . CW3 F 6 .   ? 141.298 125.378 94.711  1.00 152.87 ?  401 CW3 A C07 1 
HETATM 8717 C C08 . CW3 F 6 .   ? 140.006 124.866 94.960  1.00 152.87 ?  401 CW3 A C08 1 
HETATM 8718 C C09 . CW3 F 6 .   ? 139.536 123.844 94.130  1.00 152.87 ?  401 CW3 A C09 1 
HETATM 8719 C C10 . CW3 F 6 .   ? 140.323 123.408 93.073  1.00 152.87 ?  401 CW3 A C10 1 
HETATM 8720 N N11 . CW3 F 6 .   ? 139.856 122.308 92.324  1.00 152.87 1  401 CW3 A N11 1 
HETATM 8721 O O12 . CW3 F 6 .   ? 140.024 121.184 92.761  1.00 152.87 -1 401 CW3 A O12 1 
HETATM 8722 O O13 . CW3 F 6 .   ? 139.263 122.439 91.264  1.00 152.87 ?  401 CW3 A O13 1 
HETATM 8723 C C14 . CW3 F 6 .   ? 139.143 125.380 96.024  1.00 152.87 ?  401 CW3 A C14 1 
HETATM 8724 O O15 . CW3 F 6 .   ? 139.228 126.568 96.447  1.00 152.87 -1 401 CW3 A O15 1 
HETATM 8725 O O16 . CW3 F 6 .   ? 138.212 124.665 96.481  1.00 152.87 ?  401 CW3 A O16 1 
# 
