data_9JD6
# 
_entry.id   9JD6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JD6         pdb_00009jd6 10.2210/pdb9jd6/pdb 
WWPDB D_1300051027 ?            ?                   
EMDB  EMD-61382    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JD6 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of human TauT in presence of Piperidine-4-sulfonate, determined in an inward-facing occluded conformation' 
_pdbx_database_related.db_id          EMD-61382 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              qqh@fudan.edu.cn 
_pdbx_contact_author.name_first         Qianhui 
_pdbx_contact_author.name_last          Qu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5753-2599 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Qu, Q.'   1 0000-0002-5753-2599 
'Chao, Y.' 2 0009-0005-2230-1167 
'Zhou, Z.' 3 0000-0002-2432-4283 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Res.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1001-0602 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Transport and inhibition mechanism for human TauT-mediated taurine uptake.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41422-025-01076-w 
_citation.pdbx_database_id_PubMed   39837997 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chao, Y.'   1  ?                   
primary 'Zhou, Z.'   2  ?                   
primary 'Xia, H.'    3  ?                   
primary 'Yang, C.'   4  ?                   
primary 'Li, T.'     5  0000-0003-3146-2761 
primary 'Tang, Y.Q.' 6  ?                   
primary 'Shu, Y.'    7  0000-0001-8893-434X 
primary 'Ba, Q.'     8  ?                   
primary 'Hong, J.'   9  0000-0001-9912-633X 
primary 'Li, D.'     10 0000-0003-4729-4678 
primary 'Qu, Q.'     11 0000-0002-5753-2599 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sodium- and chloride-dependent taurine transporter' 68495.992 1 ? ? ? ? 
2 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose             221.208   3 ? ? ? ? 
3 non-polymer syn 'CHLORIDE ION'                                       35.453    1 ? ? ? ? 
4 non-polymer syn 'CHOLESTEROL HEMISUCCINATE'                          486.726   2 ? ? ? ? 
5 non-polymer syn 'SODIUM ION'                                         22.990    1 ? ? ? ? 
6 non-polymer syn 'piperidine-4-sulfonic acid'                         165.211   1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 6 member 6' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL
IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY
NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL
DSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV
IVIRLCQTEGPFLVRVKYLLTPSRLEEELRRRTEPGLRSRLEVLFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL
IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY
NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL
DSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV
IVIRLCQTEGPFLVRVKYLLTPSRLEEELRRRTEPGLRSRLEVLFQ
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 2-acetamido-2-deoxy-beta-D-glucopyranose NAG   
3 'CHLORIDE ION'                           CL    
4 'CHOLESTEROL HEMISUCCINATE'              Y01   
5 'SODIUM ION'                             NA    
6 'piperidine-4-sulfonic acid'             A1EBD 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   THR n 
1 4   LYS n 
1 5   GLU n 
1 6   LYS n 
1 7   LEU n 
1 8   GLN n 
1 9   CYS n 
1 10  LEU n 
1 11  LYS n 
1 12  ASP n 
1 13  PHE n 
1 14  HIS n 
1 15  LYS n 
1 16  ASP n 
1 17  ILE n 
1 18  LEU n 
1 19  LYS n 
1 20  PRO n 
1 21  SER n 
1 22  PRO n 
1 23  GLY n 
1 24  LYS n 
1 25  SER n 
1 26  PRO n 
1 27  GLY n 
1 28  THR n 
1 29  ARG n 
1 30  PRO n 
1 31  GLU n 
1 32  ASP n 
1 33  GLU n 
1 34  ALA n 
1 35  GLU n 
1 36  GLY n 
1 37  LYS n 
1 38  PRO n 
1 39  PRO n 
1 40  GLN n 
1 41  ARG n 
1 42  GLU n 
1 43  LYS n 
1 44  TRP n 
1 45  SER n 
1 46  SER n 
1 47  LYS n 
1 48  ILE n 
1 49  ASP n 
1 50  PHE n 
1 51  VAL n 
1 52  LEU n 
1 53  SER n 
1 54  VAL n 
1 55  ALA n 
1 56  GLY n 
1 57  GLY n 
1 58  PHE n 
1 59  VAL n 
1 60  GLY n 
1 61  LEU n 
1 62  GLY n 
1 63  ASN n 
1 64  VAL n 
1 65  TRP n 
1 66  ARG n 
1 67  PHE n 
1 68  PRO n 
1 69  TYR n 
1 70  LEU n 
1 71  CYS n 
1 72  TYR n 
1 73  LYS n 
1 74  ASN n 
1 75  GLY n 
1 76  GLY n 
1 77  GLY n 
1 78  ALA n 
1 79  PHE n 
1 80  LEU n 
1 81  ILE n 
1 82  PRO n 
1 83  TYR n 
1 84  PHE n 
1 85  ILE n 
1 86  PHE n 
1 87  LEU n 
1 88  PHE n 
1 89  GLY n 
1 90  SER n 
1 91  GLY n 
1 92  LEU n 
1 93  PRO n 
1 94  VAL n 
1 95  PHE n 
1 96  PHE n 
1 97  LEU n 
1 98  GLU n 
1 99  ILE n 
1 100 ILE n 
1 101 ILE n 
1 102 GLY n 
1 103 GLN n 
1 104 TYR n 
1 105 THR n 
1 106 SER n 
1 107 GLU n 
1 108 GLY n 
1 109 GLY n 
1 110 ILE n 
1 111 THR n 
1 112 CYS n 
1 113 TRP n 
1 114 GLU n 
1 115 LYS n 
1 116 ILE n 
1 117 CYS n 
1 118 PRO n 
1 119 LEU n 
1 120 PHE n 
1 121 SER n 
1 122 GLY n 
1 123 ILE n 
1 124 GLY n 
1 125 TYR n 
1 126 ALA n 
1 127 SER n 
1 128 VAL n 
1 129 VAL n 
1 130 ILE n 
1 131 VAL n 
1 132 SER n 
1 133 LEU n 
1 134 LEU n 
1 135 ASN n 
1 136 VAL n 
1 137 TYR n 
1 138 TYR n 
1 139 ILE n 
1 140 VAL n 
1 141 ILE n 
1 142 LEU n 
1 143 ALA n 
1 144 TRP n 
1 145 ALA n 
1 146 THR n 
1 147 TYR n 
1 148 TYR n 
1 149 LEU n 
1 150 PHE n 
1 151 GLN n 
1 152 SER n 
1 153 PHE n 
1 154 GLN n 
1 155 LYS n 
1 156 GLU n 
1 157 LEU n 
1 158 PRO n 
1 159 TRP n 
1 160 ALA n 
1 161 HIS n 
1 162 CYS n 
1 163 ASN n 
1 164 HIS n 
1 165 SER n 
1 166 TRP n 
1 167 ASN n 
1 168 THR n 
1 169 PRO n 
1 170 HIS n 
1 171 CYS n 
1 172 MET n 
1 173 GLU n 
1 174 ASP n 
1 175 THR n 
1 176 MET n 
1 177 ARG n 
1 178 LYS n 
1 179 ASN n 
1 180 LYS n 
1 181 SER n 
1 182 VAL n 
1 183 TRP n 
1 184 ILE n 
1 185 THR n 
1 186 ILE n 
1 187 SER n 
1 188 SER n 
1 189 THR n 
1 190 ASN n 
1 191 PHE n 
1 192 THR n 
1 193 SER n 
1 194 PRO n 
1 195 VAL n 
1 196 ILE n 
1 197 GLU n 
1 198 PHE n 
1 199 TRP n 
1 200 GLU n 
1 201 ARG n 
1 202 ASN n 
1 203 VAL n 
1 204 LEU n 
1 205 SER n 
1 206 LEU n 
1 207 SER n 
1 208 PRO n 
1 209 GLY n 
1 210 ILE n 
1 211 ASP n 
1 212 HIS n 
1 213 PRO n 
1 214 GLY n 
1 215 SER n 
1 216 LEU n 
1 217 LYS n 
1 218 TRP n 
1 219 ASP n 
1 220 LEU n 
1 221 ALA n 
1 222 LEU n 
1 223 CYS n 
1 224 LEU n 
1 225 LEU n 
1 226 LEU n 
1 227 VAL n 
1 228 TRP n 
1 229 LEU n 
1 230 VAL n 
1 231 CYS n 
1 232 PHE n 
1 233 PHE n 
1 234 CYS n 
1 235 ILE n 
1 236 TRP n 
1 237 LYS n 
1 238 GLY n 
1 239 VAL n 
1 240 ARG n 
1 241 SER n 
1 242 THR n 
1 243 GLY n 
1 244 LYS n 
1 245 VAL n 
1 246 VAL n 
1 247 TYR n 
1 248 PHE n 
1 249 THR n 
1 250 ALA n 
1 251 THR n 
1 252 PHE n 
1 253 PRO n 
1 254 PHE n 
1 255 ALA n 
1 256 MET n 
1 257 LEU n 
1 258 LEU n 
1 259 VAL n 
1 260 LEU n 
1 261 LEU n 
1 262 VAL n 
1 263 ARG n 
1 264 GLY n 
1 265 LEU n 
1 266 THR n 
1 267 LEU n 
1 268 PRO n 
1 269 GLY n 
1 270 ALA n 
1 271 GLY n 
1 272 ALA n 
1 273 GLY n 
1 274 ILE n 
1 275 LYS n 
1 276 PHE n 
1 277 TYR n 
1 278 LEU n 
1 279 TYR n 
1 280 PRO n 
1 281 ASP n 
1 282 ILE n 
1 283 THR n 
1 284 ARG n 
1 285 LEU n 
1 286 GLU n 
1 287 ASP n 
1 288 PRO n 
1 289 GLN n 
1 290 VAL n 
1 291 TRP n 
1 292 ILE n 
1 293 ASP n 
1 294 ALA n 
1 295 GLY n 
1 296 THR n 
1 297 GLN n 
1 298 ILE n 
1 299 PHE n 
1 300 PHE n 
1 301 SER n 
1 302 TYR n 
1 303 ALA n 
1 304 ILE n 
1 305 CYS n 
1 306 LEU n 
1 307 GLY n 
1 308 ALA n 
1 309 MET n 
1 310 THR n 
1 311 SER n 
1 312 LEU n 
1 313 GLY n 
1 314 SER n 
1 315 TYR n 
1 316 ASN n 
1 317 LYS n 
1 318 TYR n 
1 319 LYS n 
1 320 TYR n 
1 321 ASN n 
1 322 SER n 
1 323 TYR n 
1 324 ARG n 
1 325 ASP n 
1 326 CYS n 
1 327 MET n 
1 328 LEU n 
1 329 LEU n 
1 330 GLY n 
1 331 CYS n 
1 332 LEU n 
1 333 ASN n 
1 334 SER n 
1 335 GLY n 
1 336 THR n 
1 337 SER n 
1 338 PHE n 
1 339 VAL n 
1 340 SER n 
1 341 GLY n 
1 342 PHE n 
1 343 ALA n 
1 344 ILE n 
1 345 PHE n 
1 346 SER n 
1 347 ILE n 
1 348 LEU n 
1 349 GLY n 
1 350 PHE n 
1 351 MET n 
1 352 ALA n 
1 353 GLN n 
1 354 GLU n 
1 355 GLN n 
1 356 GLY n 
1 357 VAL n 
1 358 ASP n 
1 359 ILE n 
1 360 ALA n 
1 361 ASP n 
1 362 VAL n 
1 363 ALA n 
1 364 GLU n 
1 365 SER n 
1 366 GLY n 
1 367 PRO n 
1 368 GLY n 
1 369 LEU n 
1 370 ALA n 
1 371 PHE n 
1 372 ILE n 
1 373 ALA n 
1 374 TYR n 
1 375 PRO n 
1 376 LYS n 
1 377 ALA n 
1 378 VAL n 
1 379 THR n 
1 380 MET n 
1 381 MET n 
1 382 PRO n 
1 383 LEU n 
1 384 PRO n 
1 385 THR n 
1 386 PHE n 
1 387 TRP n 
1 388 SER n 
1 389 ILE n 
1 390 LEU n 
1 391 PHE n 
1 392 PHE n 
1 393 ILE n 
1 394 MET n 
1 395 LEU n 
1 396 LEU n 
1 397 LEU n 
1 398 LEU n 
1 399 GLY n 
1 400 LEU n 
1 401 ASP n 
1 402 SER n 
1 403 GLN n 
1 404 PHE n 
1 405 VAL n 
1 406 GLU n 
1 407 VAL n 
1 408 GLU n 
1 409 GLY n 
1 410 GLN n 
1 411 ILE n 
1 412 THR n 
1 413 SER n 
1 414 LEU n 
1 415 VAL n 
1 416 ASP n 
1 417 LEU n 
1 418 TYR n 
1 419 PRO n 
1 420 SER n 
1 421 PHE n 
1 422 LEU n 
1 423 ARG n 
1 424 LYS n 
1 425 GLY n 
1 426 TYR n 
1 427 ARG n 
1 428 ARG n 
1 429 GLU n 
1 430 ILE n 
1 431 PHE n 
1 432 ILE n 
1 433 ALA n 
1 434 PHE n 
1 435 VAL n 
1 436 CYS n 
1 437 SER n 
1 438 ILE n 
1 439 SER n 
1 440 TYR n 
1 441 LEU n 
1 442 LEU n 
1 443 GLY n 
1 444 LEU n 
1 445 THR n 
1 446 MET n 
1 447 VAL n 
1 448 THR n 
1 449 GLU n 
1 450 GLY n 
1 451 GLY n 
1 452 MET n 
1 453 TYR n 
1 454 VAL n 
1 455 PHE n 
1 456 GLN n 
1 457 LEU n 
1 458 PHE n 
1 459 ASP n 
1 460 TYR n 
1 461 TYR n 
1 462 ALA n 
1 463 ALA n 
1 464 SER n 
1 465 GLY n 
1 466 VAL n 
1 467 CYS n 
1 468 LEU n 
1 469 LEU n 
1 470 TRP n 
1 471 VAL n 
1 472 ALA n 
1 473 PHE n 
1 474 PHE n 
1 475 GLU n 
1 476 CYS n 
1 477 PHE n 
1 478 VAL n 
1 479 ILE n 
1 480 ALA n 
1 481 TRP n 
1 482 ILE n 
1 483 TYR n 
1 484 GLY n 
1 485 GLY n 
1 486 ASP n 
1 487 ASN n 
1 488 LEU n 
1 489 TYR n 
1 490 ASP n 
1 491 GLY n 
1 492 ILE n 
1 493 GLU n 
1 494 ASP n 
1 495 MET n 
1 496 ILE n 
1 497 GLY n 
1 498 TYR n 
1 499 ARG n 
1 500 PRO n 
1 501 GLY n 
1 502 PRO n 
1 503 TRP n 
1 504 MET n 
1 505 LYS n 
1 506 TYR n 
1 507 SER n 
1 508 TRP n 
1 509 ALA n 
1 510 VAL n 
1 511 ILE n 
1 512 THR n 
1 513 PRO n 
1 514 VAL n 
1 515 LEU n 
1 516 CYS n 
1 517 VAL n 
1 518 GLY n 
1 519 CYS n 
1 520 PHE n 
1 521 ILE n 
1 522 PHE n 
1 523 SER n 
1 524 LEU n 
1 525 VAL n 
1 526 LYS n 
1 527 TYR n 
1 528 VAL n 
1 529 PRO n 
1 530 LEU n 
1 531 THR n 
1 532 TYR n 
1 533 ASN n 
1 534 LYS n 
1 535 THR n 
1 536 TYR n 
1 537 VAL n 
1 538 TYR n 
1 539 PRO n 
1 540 ASN n 
1 541 TRP n 
1 542 ALA n 
1 543 ILE n 
1 544 GLY n 
1 545 LEU n 
1 546 GLY n 
1 547 TRP n 
1 548 SER n 
1 549 LEU n 
1 550 ALA n 
1 551 LEU n 
1 552 SER n 
1 553 SER n 
1 554 MET n 
1 555 LEU n 
1 556 CYS n 
1 557 VAL n 
1 558 PRO n 
1 559 LEU n 
1 560 VAL n 
1 561 ILE n 
1 562 VAL n 
1 563 ILE n 
1 564 ARG n 
1 565 LEU n 
1 566 CYS n 
1 567 GLN n 
1 568 THR n 
1 569 GLU n 
1 570 GLY n 
1 571 PRO n 
1 572 PHE n 
1 573 LEU n 
1 574 VAL n 
1 575 ARG n 
1 576 VAL n 
1 577 LYS n 
1 578 TYR n 
1 579 LEU n 
1 580 LEU n 
1 581 THR n 
1 582 PRO n 
1 583 SER n 
1 584 ARG n 
1 585 LEU n 
1 586 GLU n 
1 587 GLU n 
1 588 GLU n 
1 589 LEU n 
1 590 ARG n 
1 591 ARG n 
1 592 ARG n 
1 593 THR n 
1 594 GLU n 
1 595 PRO n 
1 596 GLY n 
1 597 LEU n 
1 598 ARG n 
1 599 SER n 
1 600 ARG n 
1 601 LEU n 
1 602 GLU n 
1 603 VAL n 
1 604 LEU n 
1 605 PHE n 
1 606 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   606 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC6A6 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               human 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK293F 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1EBD non-polymer                  . 'piperidine-4-sulfonic acid'             ? 'C5 H11 N O3 S'  165.211 
ALA   'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CL    non-polymer                  . 'CHLORIDE ION'                           ? 'Cl -1'          35.453  
CYS   'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NA    non-polymer                  . 'SODIUM ION'                             ? 'Na 1'           22.990  
NAG   'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE   'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
Y01   non-polymer                  . 'CHOLESTEROL HEMISUCCINATE'              ? 'C31 H50 O4'     486.726 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   THR 3   3   ?   ?   ?   A . n 
A 1 4   LYS 4   4   ?   ?   ?   A . n 
A 1 5   GLU 5   5   ?   ?   ?   A . n 
A 1 6   LYS 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   GLN 8   8   ?   ?   ?   A . n 
A 1 9   CYS 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  LYS 11  11  ?   ?   ?   A . n 
A 1 12  ASP 12  12  ?   ?   ?   A . n 
A 1 13  PHE 13  13  ?   ?   ?   A . n 
A 1 14  HIS 14  14  ?   ?   ?   A . n 
A 1 15  LYS 15  15  ?   ?   ?   A . n 
A 1 16  ASP 16  16  ?   ?   ?   A . n 
A 1 17  ILE 17  17  ?   ?   ?   A . n 
A 1 18  LEU 18  18  ?   ?   ?   A . n 
A 1 19  LYS 19  19  ?   ?   ?   A . n 
A 1 20  PRO 20  20  ?   ?   ?   A . n 
A 1 21  SER 21  21  ?   ?   ?   A . n 
A 1 22  PRO 22  22  ?   ?   ?   A . n 
A 1 23  GLY 23  23  ?   ?   ?   A . n 
A 1 24  LYS 24  24  ?   ?   ?   A . n 
A 1 25  SER 25  25  ?   ?   ?   A . n 
A 1 26  PRO 26  26  ?   ?   ?   A . n 
A 1 27  GLY 27  27  ?   ?   ?   A . n 
A 1 28  THR 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  ?   ?   ?   A . n 
A 1 30  PRO 30  30  ?   ?   ?   A . n 
A 1 31  GLU 31  31  ?   ?   ?   A . n 
A 1 32  ASP 32  32  ?   ?   ?   A . n 
A 1 33  GLU 33  33  ?   ?   ?   A . n 
A 1 34  ALA 34  34  ?   ?   ?   A . n 
A 1 35  GLU 35  35  ?   ?   ?   A . n 
A 1 36  GLY 36  36  ?   ?   ?   A . n 
A 1 37  LYS 37  37  ?   ?   ?   A . n 
A 1 38  PRO 38  38  ?   ?   ?   A . n 
A 1 39  PRO 39  39  ?   ?   ?   A . n 
A 1 40  GLN 40  40  ?   ?   ?   A . n 
A 1 41  ARG 41  41  41  ARG ARG A . n 
A 1 42  GLU 42  42  42  GLU GLU A . n 
A 1 43  LYS 43  43  43  LYS LYS A . n 
A 1 44  TRP 44  44  44  TRP TRP A . n 
A 1 45  SER 45  45  45  SER SER A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  LYS 47  47  47  LYS LYS A . n 
A 1 48  ILE 48  48  48  ILE ILE A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  PHE 50  50  50  PHE PHE A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  VAL 54  54  54  VAL VAL A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  GLY 56  56  56  GLY GLY A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  PHE 58  58  58  PHE PHE A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  VAL 64  64  64  VAL VAL A . n 
A 1 65  TRP 65  65  65  TRP TRP A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  PHE 67  67  67  PHE PHE A . n 
A 1 68  PRO 68  68  68  PRO PRO A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  CYS 71  71  71  CYS CYS A . n 
A 1 72  TYR 72  72  72  TYR TYR A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  PHE 79  79  79  PHE PHE A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  TYR 83  83  83  TYR TYR A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  PRO 93  93  93  PRO PRO A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  PHE 95  95  95  PHE PHE A . n 
A 1 96  PHE 96  96  96  PHE PHE A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  ILE 99  99  99  ILE ILE A . n 
A 1 100 ILE 100 100 100 ILE ILE A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 GLN 103 103 103 GLN GLN A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 THR 105 105 105 THR THR A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 GLY 108 108 108 GLY GLY A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ILE 110 110 110 ILE ILE A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 CYS 112 112 112 CYS CYS A . n 
A 1 113 TRP 113 113 113 TRP TRP A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 LYS 115 115 115 LYS LYS A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 CYS 117 117 117 CYS CYS A . n 
A 1 118 PRO 118 118 118 PRO PRO A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 SER 127 127 127 SER SER A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 VAL 129 129 129 VAL VAL A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 TYR 138 138 138 TYR TYR A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 TRP 144 144 144 TRP TRP A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 THR 146 146 146 THR THR A . n 
A 1 147 TYR 147 147 147 TYR TYR A . n 
A 1 148 TYR 148 148 148 TYR TYR A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 GLN 151 151 151 GLN GLN A . n 
A 1 152 SER 152 152 152 SER SER A . n 
A 1 153 PHE 153 153 153 PHE PHE A . n 
A 1 154 GLN 154 154 154 GLN GLN A . n 
A 1 155 LYS 155 155 155 LYS LYS A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 TRP 159 159 159 TRP TRP A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 HIS 161 161 161 HIS HIS A . n 
A 1 162 CYS 162 162 162 CYS CYS A . n 
A 1 163 ASN 163 163 163 ASN ASN A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 TRP 166 166 166 TRP TRP A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 HIS 170 170 170 HIS HIS A . n 
A 1 171 CYS 171 171 171 CYS CYS A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ASP 174 174 174 ASP ASP A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 ARG 177 177 177 ARG ARG A . n 
A 1 178 LYS 178 178 178 LYS LYS A . n 
A 1 179 ASN 179 179 179 ASN ASN A . n 
A 1 180 LYS 180 180 ?   ?   ?   A . n 
A 1 181 SER 181 181 ?   ?   ?   A . n 
A 1 182 VAL 182 182 ?   ?   ?   A . n 
A 1 183 TRP 183 183 ?   ?   ?   A . n 
A 1 184 ILE 184 184 ?   ?   ?   A . n 
A 1 185 THR 185 185 ?   ?   ?   A . n 
A 1 186 ILE 186 186 ?   ?   ?   A . n 
A 1 187 SER 187 187 ?   ?   ?   A . n 
A 1 188 SER 188 188 ?   ?   ?   A . n 
A 1 189 THR 189 189 189 THR THR A . n 
A 1 190 ASN 190 190 190 ASN ASN A . n 
A 1 191 PHE 191 191 191 PHE PHE A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 TRP 199 199 199 TRP TRP A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 ARG 201 201 201 ARG ARG A . n 
A 1 202 ASN 202 202 202 ASN ASN A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 PRO 208 208 208 PRO PRO A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 ILE 210 210 210 ILE ILE A . n 
A 1 211 ASP 211 211 211 ASP ASP A . n 
A 1 212 HIS 212 212 212 HIS HIS A . n 
A 1 213 PRO 213 213 213 PRO PRO A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 SER 215 215 215 SER SER A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 LYS 217 217 217 LYS LYS A . n 
A 1 218 TRP 218 218 218 TRP TRP A . n 
A 1 219 ASP 219 219 219 ASP ASP A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ALA 221 221 221 ALA ALA A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 CYS 223 223 223 CYS CYS A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 LEU 225 225 225 LEU LEU A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 VAL 227 227 227 VAL VAL A . n 
A 1 228 TRP 228 228 228 TRP TRP A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 CYS 231 231 231 CYS CYS A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 PHE 233 233 233 PHE PHE A . n 
A 1 234 CYS 234 234 234 CYS CYS A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 TRP 236 236 236 TRP TRP A . n 
A 1 237 LYS 237 237 237 LYS LYS A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 ARG 240 240 240 ARG ARG A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 LYS 244 244 244 LYS LYS A . n 
A 1 245 VAL 245 245 245 VAL VAL A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 PHE 248 248 248 PHE PHE A . n 
A 1 249 THR 249 249 249 THR THR A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 THR 251 251 251 THR THR A . n 
A 1 252 PHE 252 252 252 PHE PHE A . n 
A 1 253 PRO 253 253 253 PRO PRO A . n 
A 1 254 PHE 254 254 254 PHE PHE A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 MET 256 256 256 MET MET A . n 
A 1 257 LEU 257 257 257 LEU LEU A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 VAL 259 259 259 VAL VAL A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 GLY 264 264 264 GLY GLY A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 PRO 268 268 268 PRO PRO A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 GLY 273 273 273 GLY GLY A . n 
A 1 274 ILE 274 274 274 ILE ILE A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 PHE 276 276 276 PHE PHE A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 TYR 279 279 279 TYR TYR A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 ASP 281 281 281 ASP ASP A . n 
A 1 282 ILE 282 282 282 ILE ILE A . n 
A 1 283 THR 283 283 283 THR THR A . n 
A 1 284 ARG 284 284 284 ARG ARG A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 GLN 289 289 289 GLN GLN A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 TRP 291 291 291 TRP TRP A . n 
A 1 292 ILE 292 292 292 ILE ILE A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 ALA 294 294 294 ALA ALA A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 ILE 298 298 298 ILE ILE A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 PHE 300 300 300 PHE PHE A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 ILE 304 304 304 ILE ILE A . n 
A 1 305 CYS 305 305 305 CYS CYS A . n 
A 1 306 LEU 306 306 306 LEU LEU A . n 
A 1 307 GLY 307 307 307 GLY GLY A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 MET 309 309 309 MET MET A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 GLY 313 313 313 GLY GLY A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 TYR 315 315 315 TYR TYR A . n 
A 1 316 ASN 316 316 316 ASN ASN A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 LYS 319 319 319 LYS LYS A . n 
A 1 320 TYR 320 320 320 TYR TYR A . n 
A 1 321 ASN 321 321 321 ASN ASN A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 CYS 326 326 326 CYS CYS A . n 
A 1 327 MET 327 327 327 MET MET A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 CYS 331 331 331 CYS CYS A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 ASN 333 333 333 ASN ASN A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 GLY 335 335 335 GLY GLY A . n 
A 1 336 THR 336 336 336 THR THR A . n 
A 1 337 SER 337 337 337 SER SER A . n 
A 1 338 PHE 338 338 338 PHE PHE A . n 
A 1 339 VAL 339 339 339 VAL VAL A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 GLY 341 341 341 GLY GLY A . n 
A 1 342 PHE 342 342 342 PHE PHE A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 PHE 345 345 345 PHE PHE A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 ILE 347 347 347 ILE ILE A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 PHE 350 350 350 PHE PHE A . n 
A 1 351 MET 351 351 351 MET MET A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 GLN 353 353 353 GLN GLN A . n 
A 1 354 GLU 354 354 354 GLU GLU A . n 
A 1 355 GLN 355 355 355 GLN GLN A . n 
A 1 356 GLY 356 356 356 GLY GLY A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ASP 358 358 358 ASP ASP A . n 
A 1 359 ILE 359 359 359 ILE ILE A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ASP 361 361 361 ASP ASP A . n 
A 1 362 VAL 362 362 362 VAL VAL A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 GLU 364 364 364 GLU GLU A . n 
A 1 365 SER 365 365 365 SER SER A . n 
A 1 366 GLY 366 366 366 GLY GLY A . n 
A 1 367 PRO 367 367 367 PRO PRO A . n 
A 1 368 GLY 368 368 368 GLY GLY A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 PHE 371 371 371 PHE PHE A . n 
A 1 372 ILE 372 372 372 ILE ILE A . n 
A 1 373 ALA 373 373 373 ALA ALA A . n 
A 1 374 TYR 374 374 374 TYR TYR A . n 
A 1 375 PRO 375 375 375 PRO PRO A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 VAL 378 378 378 VAL VAL A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 MET 380 380 380 MET MET A . n 
A 1 381 MET 381 381 381 MET MET A . n 
A 1 382 PRO 382 382 382 PRO PRO A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 PRO 384 384 384 PRO PRO A . n 
A 1 385 THR 385 385 385 THR THR A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 TRP 387 387 387 TRP TRP A . n 
A 1 388 SER 388 388 388 SER SER A . n 
A 1 389 ILE 389 389 389 ILE ILE A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 ILE 393 393 393 ILE ILE A . n 
A 1 394 MET 394 394 394 MET MET A . n 
A 1 395 LEU 395 395 395 LEU LEU A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 GLY 399 399 399 GLY GLY A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ASP 401 401 401 ASP ASP A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 GLN 403 403 403 GLN GLN A . n 
A 1 404 PHE 404 404 404 PHE PHE A . n 
A 1 405 VAL 405 405 405 VAL VAL A . n 
A 1 406 GLU 406 406 406 GLU GLU A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 GLU 408 408 408 GLU GLU A . n 
A 1 409 GLY 409 409 409 GLY GLY A . n 
A 1 410 GLN 410 410 410 GLN GLN A . n 
A 1 411 ILE 411 411 411 ILE ILE A . n 
A 1 412 THR 412 412 412 THR THR A . n 
A 1 413 SER 413 413 413 SER SER A . n 
A 1 414 LEU 414 414 414 LEU LEU A . n 
A 1 415 VAL 415 415 415 VAL VAL A . n 
A 1 416 ASP 416 416 416 ASP ASP A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 TYR 418 418 418 TYR TYR A . n 
A 1 419 PRO 419 419 419 PRO PRO A . n 
A 1 420 SER 420 420 420 SER SER A . n 
A 1 421 PHE 421 421 421 PHE PHE A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 ARG 423 423 423 ARG ARG A . n 
A 1 424 LYS 424 424 424 LYS LYS A . n 
A 1 425 GLY 425 425 425 GLY GLY A . n 
A 1 426 TYR 426 426 426 TYR TYR A . n 
A 1 427 ARG 427 427 427 ARG ARG A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 GLU 429 429 429 GLU GLU A . n 
A 1 430 ILE 430 430 430 ILE ILE A . n 
A 1 431 PHE 431 431 431 PHE PHE A . n 
A 1 432 ILE 432 432 432 ILE ILE A . n 
A 1 433 ALA 433 433 433 ALA ALA A . n 
A 1 434 PHE 434 434 434 PHE PHE A . n 
A 1 435 VAL 435 435 435 VAL VAL A . n 
A 1 436 CYS 436 436 436 CYS CYS A . n 
A 1 437 SER 437 437 437 SER SER A . n 
A 1 438 ILE 438 438 438 ILE ILE A . n 
A 1 439 SER 439 439 439 SER SER A . n 
A 1 440 TYR 440 440 440 TYR TYR A . n 
A 1 441 LEU 441 441 441 LEU LEU A . n 
A 1 442 LEU 442 442 442 LEU LEU A . n 
A 1 443 GLY 443 443 443 GLY GLY A . n 
A 1 444 LEU 444 444 444 LEU LEU A . n 
A 1 445 THR 445 445 445 THR THR A . n 
A 1 446 MET 446 446 446 MET MET A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 THR 448 448 448 THR THR A . n 
A 1 449 GLU 449 449 449 GLU GLU A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 GLY 451 451 451 GLY GLY A . n 
A 1 452 MET 452 452 452 MET MET A . n 
A 1 453 TYR 453 453 453 TYR TYR A . n 
A 1 454 VAL 454 454 454 VAL VAL A . n 
A 1 455 PHE 455 455 455 PHE PHE A . n 
A 1 456 GLN 456 456 456 GLN GLN A . n 
A 1 457 LEU 457 457 457 LEU LEU A . n 
A 1 458 PHE 458 458 458 PHE PHE A . n 
A 1 459 ASP 459 459 459 ASP ASP A . n 
A 1 460 TYR 460 460 460 TYR TYR A . n 
A 1 461 TYR 461 461 461 TYR TYR A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 ALA 463 463 463 ALA ALA A . n 
A 1 464 SER 464 464 464 SER SER A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 CYS 467 467 467 CYS CYS A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 LEU 469 469 469 LEU LEU A . n 
A 1 470 TRP 470 470 470 TRP TRP A . n 
A 1 471 VAL 471 471 471 VAL VAL A . n 
A 1 472 ALA 472 472 472 ALA ALA A . n 
A 1 473 PHE 473 473 473 PHE PHE A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 GLU 475 475 475 GLU GLU A . n 
A 1 476 CYS 476 476 476 CYS CYS A . n 
A 1 477 PHE 477 477 477 PHE PHE A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 ILE 479 479 479 ILE ILE A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 TRP 481 481 481 TRP TRP A . n 
A 1 482 ILE 482 482 482 ILE ILE A . n 
A 1 483 TYR 483 483 483 TYR TYR A . n 
A 1 484 GLY 484 484 484 GLY GLY A . n 
A 1 485 GLY 485 485 485 GLY GLY A . n 
A 1 486 ASP 486 486 486 ASP ASP A . n 
A 1 487 ASN 487 487 487 ASN ASN A . n 
A 1 488 LEU 488 488 488 LEU LEU A . n 
A 1 489 TYR 489 489 489 TYR TYR A . n 
A 1 490 ASP 490 490 490 ASP ASP A . n 
A 1 491 GLY 491 491 491 GLY GLY A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 GLU 493 493 493 GLU GLU A . n 
A 1 494 ASP 494 494 494 ASP ASP A . n 
A 1 495 MET 495 495 495 MET MET A . n 
A 1 496 ILE 496 496 496 ILE ILE A . n 
A 1 497 GLY 497 497 497 GLY GLY A . n 
A 1 498 TYR 498 498 498 TYR TYR A . n 
A 1 499 ARG 499 499 499 ARG ARG A . n 
A 1 500 PRO 500 500 500 PRO PRO A . n 
A 1 501 GLY 501 501 501 GLY GLY A . n 
A 1 502 PRO 502 502 502 PRO PRO A . n 
A 1 503 TRP 503 503 503 TRP TRP A . n 
A 1 504 MET 504 504 504 MET MET A . n 
A 1 505 LYS 505 505 505 LYS LYS A . n 
A 1 506 TYR 506 506 506 TYR TYR A . n 
A 1 507 SER 507 507 507 SER SER A . n 
A 1 508 TRP 508 508 508 TRP TRP A . n 
A 1 509 ALA 509 509 509 ALA ALA A . n 
A 1 510 VAL 510 510 510 VAL VAL A . n 
A 1 511 ILE 511 511 511 ILE ILE A . n 
A 1 512 THR 512 512 512 THR THR A . n 
A 1 513 PRO 513 513 513 PRO PRO A . n 
A 1 514 VAL 514 514 514 VAL VAL A . n 
A 1 515 LEU 515 515 515 LEU LEU A . n 
A 1 516 CYS 516 516 516 CYS CYS A . n 
A 1 517 VAL 517 517 517 VAL VAL A . n 
A 1 518 GLY 518 518 518 GLY GLY A . n 
A 1 519 CYS 519 519 519 CYS CYS A . n 
A 1 520 PHE 520 520 520 PHE PHE A . n 
A 1 521 ILE 521 521 521 ILE ILE A . n 
A 1 522 PHE 522 522 522 PHE PHE A . n 
A 1 523 SER 523 523 523 SER SER A . n 
A 1 524 LEU 524 524 524 LEU LEU A . n 
A 1 525 VAL 525 525 525 VAL VAL A . n 
A 1 526 LYS 526 526 526 LYS LYS A . n 
A 1 527 TYR 527 527 527 TYR TYR A . n 
A 1 528 VAL 528 528 528 VAL VAL A . n 
A 1 529 PRO 529 529 529 PRO PRO A . n 
A 1 530 LEU 530 530 530 LEU LEU A . n 
A 1 531 THR 531 531 531 THR THR A . n 
A 1 532 TYR 532 532 532 TYR TYR A . n 
A 1 533 ASN 533 533 533 ASN ASN A . n 
A 1 534 LYS 534 534 534 LYS LYS A . n 
A 1 535 THR 535 535 535 THR THR A . n 
A 1 536 TYR 536 536 536 TYR TYR A . n 
A 1 537 VAL 537 537 537 VAL VAL A . n 
A 1 538 TYR 538 538 538 TYR TYR A . n 
A 1 539 PRO 539 539 539 PRO PRO A . n 
A 1 540 ASN 540 540 540 ASN ASN A . n 
A 1 541 TRP 541 541 541 TRP TRP A . n 
A 1 542 ALA 542 542 542 ALA ALA A . n 
A 1 543 ILE 543 543 543 ILE ILE A . n 
A 1 544 GLY 544 544 544 GLY GLY A . n 
A 1 545 LEU 545 545 545 LEU LEU A . n 
A 1 546 GLY 546 546 546 GLY GLY A . n 
A 1 547 TRP 547 547 547 TRP TRP A . n 
A 1 548 SER 548 548 548 SER SER A . n 
A 1 549 LEU 549 549 549 LEU LEU A . n 
A 1 550 ALA 550 550 550 ALA ALA A . n 
A 1 551 LEU 551 551 551 LEU LEU A . n 
A 1 552 SER 552 552 552 SER SER A . n 
A 1 553 SER 553 553 553 SER SER A . n 
A 1 554 MET 554 554 554 MET MET A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 CYS 556 556 556 CYS CYS A . n 
A 1 557 VAL 557 557 557 VAL VAL A . n 
A 1 558 PRO 558 558 558 PRO PRO A . n 
A 1 559 LEU 559 559 559 LEU LEU A . n 
A 1 560 VAL 560 560 560 VAL VAL A . n 
A 1 561 ILE 561 561 561 ILE ILE A . n 
A 1 562 VAL 562 562 562 VAL VAL A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 ARG 564 564 564 ARG ARG A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 CYS 566 566 566 CYS CYS A . n 
A 1 567 GLN 567 567 567 GLN GLN A . n 
A 1 568 THR 568 568 ?   ?   ?   A . n 
A 1 569 GLU 569 569 ?   ?   ?   A . n 
A 1 570 GLY 570 570 ?   ?   ?   A . n 
A 1 571 PRO 571 571 ?   ?   ?   A . n 
A 1 572 PHE 572 572 ?   ?   ?   A . n 
A 1 573 LEU 573 573 ?   ?   ?   A . n 
A 1 574 VAL 574 574 ?   ?   ?   A . n 
A 1 575 ARG 575 575 ?   ?   ?   A . n 
A 1 576 VAL 576 576 ?   ?   ?   A . n 
A 1 577 LYS 577 577 ?   ?   ?   A . n 
A 1 578 TYR 578 578 ?   ?   ?   A . n 
A 1 579 LEU 579 579 ?   ?   ?   A . n 
A 1 580 LEU 580 580 ?   ?   ?   A . n 
A 1 581 THR 581 581 ?   ?   ?   A . n 
A 1 582 PRO 582 582 ?   ?   ?   A . n 
A 1 583 SER 583 583 ?   ?   ?   A . n 
A 1 584 ARG 584 584 ?   ?   ?   A . n 
A 1 585 LEU 585 585 ?   ?   ?   A . n 
A 1 586 GLU 586 586 ?   ?   ?   A . n 
A 1 587 GLU 587 587 ?   ?   ?   A . n 
A 1 588 GLU 588 588 ?   ?   ?   A . n 
A 1 589 LEU 589 589 ?   ?   ?   A . n 
A 1 590 ARG 590 590 ?   ?   ?   A . n 
A 1 591 ARG 591 591 ?   ?   ?   A . n 
A 1 592 ARG 592 592 ?   ?   ?   A . n 
A 1 593 THR 593 593 ?   ?   ?   A . n 
A 1 594 GLU 594 594 ?   ?   ?   A . n 
A 1 595 PRO 595 595 ?   ?   ?   A . n 
A 1 596 GLY 596 596 ?   ?   ?   A . n 
A 1 597 LEU 597 597 ?   ?   ?   A . n 
A 1 598 ARG 598 598 ?   ?   ?   A . n 
A 1 599 SER 599 599 ?   ?   ?   A . n 
A 1 600 ARG 600 600 ?   ?   ?   A . n 
A 1 601 LEU 601 601 ?   ?   ?   A . n 
A 1 602 GLU 602 602 ?   ?   ?   A . n 
A 1 603 VAL 603 603 ?   ?   ?   A . n 
A 1 604 LEU 604 604 ?   ?   ?   A . n 
A 1 605 PHE 605 605 ?   ?   ?   A . n 
A 1 606 GLN 606 606 ?   ?   ?   A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CL    ? ? CL    ? ? 'SUBJECT OF INVESTIGATION' ? 
2 NA    ? ? NA    ? ? 'SUBJECT OF INVESTIGATION' ? 
3 NAG   ? ? NAG   ? ? 'SUBJECT OF INVESTIGATION' ? 
4 A1EBD ? ? A1EBD ? ? 'SUBJECT OF INVESTIGATION' ? 
5 Y01   ? ? Y01   ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 NAG   1 701 568 NAG   NAG A . 
C 2 NAG   1 702 569 NAG   NAG A . 
D 2 NAG   1 703 570 NAG   NAG A . 
E 3 CL    1 704 573 CL    CL  A . 
F 4 Y01   1 705 574 Y01   Y01 A . 
G 4 Y01   1 706 575 Y01   Y01 A . 
H 5 NA    1 707 576 NA    NA  A . 
I 6 A1EBD 1 708 -2  A1EBD P4S A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 41  ? CG  ? A ARG 41  CG  
2  1 Y 1 A ARG 41  ? CD  ? A ARG 41  CD  
3  1 Y 1 A ARG 41  ? NE  ? A ARG 41  NE  
4  1 Y 1 A ARG 41  ? CZ  ? A ARG 41  CZ  
5  1 Y 1 A ARG 41  ? NH1 ? A ARG 41  NH1 
6  1 Y 1 A ARG 41  ? NH2 ? A ARG 41  NH2 
7  1 Y 1 A TRP 44  ? CG  ? A TRP 44  CG  
8  1 Y 1 A TRP 44  ? CD1 ? A TRP 44  CD1 
9  1 Y 1 A TRP 44  ? CD2 ? A TRP 44  CD2 
10 1 Y 1 A TRP 44  ? NE1 ? A TRP 44  NE1 
11 1 Y 1 A TRP 44  ? CE2 ? A TRP 44  CE2 
12 1 Y 1 A TRP 44  ? CE3 ? A TRP 44  CE3 
13 1 Y 1 A TRP 44  ? CZ2 ? A TRP 44  CZ2 
14 1 Y 1 A TRP 44  ? CZ3 ? A TRP 44  CZ3 
15 1 Y 1 A TRP 44  ? CH2 ? A TRP 44  CH2 
16 1 Y 1 A THR 535 ? OG1 ? A THR 535 OG1 
17 1 Y 1 A THR 535 ? CG2 ? A THR 535 CG2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JD6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JD6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JD6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9JD6 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 4367 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.627 ? 5964 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.675 ? 645  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 671  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 715  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JD6 
_struct.title                        
'Cryo-EM structure of human TauT in presence of Piperidine-4-sulfonate, determined in an inward-facing occluded conformation' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JD6 
_struct_keywords.text            
'Human Taurine transporter, Piperidine-4-sulfonate, complex, inward-facing occluded conformation, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 5 ? 
I N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SC6A6_HUMAN 
_struct_ref.pdbx_db_accession          P31641 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL
IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY
NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL
DSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV
IVIRLCQTEGPFLVRVKYLLTP
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9JD6 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 582 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P31641 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  582 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       582 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JD6 SER A 583 ? UNP P31641 ? ? 'expression tag' 583 1  
1 9JD6 ARG A 584 ? UNP P31641 ? ? 'expression tag' 584 2  
1 9JD6 LEU A 585 ? UNP P31641 ? ? 'expression tag' 585 3  
1 9JD6 GLU A 586 ? UNP P31641 ? ? 'expression tag' 586 4  
1 9JD6 GLU A 587 ? UNP P31641 ? ? 'expression tag' 587 5  
1 9JD6 GLU A 588 ? UNP P31641 ? ? 'expression tag' 588 6  
1 9JD6 LEU A 589 ? UNP P31641 ? ? 'expression tag' 589 7  
1 9JD6 ARG A 590 ? UNP P31641 ? ? 'expression tag' 590 8  
1 9JD6 ARG A 591 ? UNP P31641 ? ? 'expression tag' 591 9  
1 9JD6 ARG A 592 ? UNP P31641 ? ? 'expression tag' 592 10 
1 9JD6 THR A 593 ? UNP P31641 ? ? 'expression tag' 593 11 
1 9JD6 GLU A 594 ? UNP P31641 ? ? 'expression tag' 594 12 
1 9JD6 PRO A 595 ? UNP P31641 ? ? 'expression tag' 595 13 
1 9JD6 GLY A 596 ? UNP P31641 ? ? 'expression tag' 596 14 
1 9JD6 LEU A 597 ? UNP P31641 ? ? 'expression tag' 597 15 
1 9JD6 ARG A 598 ? UNP P31641 ? ? 'expression tag' 598 16 
1 9JD6 SER A 599 ? UNP P31641 ? ? 'expression tag' 599 17 
1 9JD6 ARG A 600 ? UNP P31641 ? ? 'expression tag' 600 18 
1 9JD6 LEU A 601 ? UNP P31641 ? ? 'expression tag' 601 19 
1 9JD6 GLU A 602 ? UNP P31641 ? ? 'expression tag' 602 20 
1 9JD6 VAL A 603 ? UNP P31641 ? ? 'expression tag' 603 21 
1 9JD6 LEU A 604 ? UNP P31641 ? ? 'expression tag' 604 22 
1 9JD6 PHE A 605 ? UNP P31641 ? ? 'expression tag' 605 23 
1 9JD6 GLN A 606 ? UNP P31641 ? ? 'expression tag' 606 24 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 46  ? VAL A 59  ? SER A 46  VAL A 59  1 ? 14 
HELX_P HELX_P2  AA2 TRP A 65  ? ASN A 74  ? TRP A 65  ASN A 74  1 ? 10 
HELX_P HELX_P3  AA3 PHE A 79  ? SER A 106 ? PHE A 79  SER A 106 1 ? 28 
HELX_P HELX_P4  AA4 GLY A 108 ? CYS A 117 ? GLY A 108 CYS A 117 1 ? 10 
HELX_P HELX_P5  AA5 SER A 121 ? SER A 152 ? SER A 121 SER A 152 1 ? 32 
HELX_P HELX_P6  AA6 LEU A 157 ? HIS A 161 ? LEU A 157 HIS A 161 5 ? 5  
HELX_P HELX_P7  AA7 SER A 193 ? ASN A 202 ? SER A 193 ASN A 202 1 ? 10 
HELX_P HELX_P8  AA8 LYS A 217 ? LYS A 237 ? LYS A 217 LYS A 237 1 ? 21 
HELX_P HELX_P9  AA9 GLY A 238 ? GLY A 243 ? GLY A 238 GLY A 243 5 ? 6  
HELX_P HELX_P10 AB1 ALA A 250 ? LEU A 267 ? ALA A 250 LEU A 267 1 ? 18 
HELX_P HELX_P11 AB2 ALA A 270 ? TYR A 279 ? ALA A 270 TYR A 279 1 ? 10 
HELX_P HELX_P12 AB3 ASP A 281 ? LEU A 285 ? ASP A 281 LEU A 285 5 ? 5  
HELX_P HELX_P13 AB4 PRO A 288 ? TYR A 302 ? PRO A 288 TYR A 302 1 ? 15 
HELX_P HELX_P14 AB5 ALA A 308 ? TYR A 315 ? ALA A 308 TYR A 315 1 ? 8  
HELX_P HELX_P15 AB6 TYR A 323 ? GLY A 356 ? TYR A 323 GLY A 356 1 ? 34 
HELX_P HELX_P16 AB7 ASP A 358 ? VAL A 362 ? ASP A 358 VAL A 362 5 ? 5  
HELX_P HELX_P17 AB8 GLY A 368 ? MET A 381 ? GLY A 368 MET A 381 1 ? 14 
HELX_P HELX_P18 AB9 LEU A 383 ? TYR A 418 ? LEU A 383 TYR A 418 1 ? 36 
HELX_P HELX_P19 AC1 ARG A 427 ? GLY A 443 ? ARG A 427 GLY A 443 1 ? 17 
HELX_P HELX_P20 AC2 LEU A 444 ? MET A 446 ? LEU A 444 MET A 446 5 ? 3  
HELX_P HELX_P21 AC3 GLY A 450 ? ALA A 462 ? GLY A 450 ALA A 462 1 ? 13 
HELX_P HELX_P22 AC4 GLY A 465 ? ILE A 482 ? GLY A 465 ILE A 482 1 ? 18 
HELX_P HELX_P23 AC5 GLY A 484 ? GLY A 497 ? GLY A 484 GLY A 497 1 ? 14 
HELX_P HELX_P24 AC6 VAL A 510 ? LYS A 526 ? VAL A 510 LYS A 526 1 ? 17 
HELX_P HELX_P25 AC7 PRO A 539 ? LEU A 555 ? PRO A 539 LEU A 555 1 ? 17 
HELX_P HELX_P26 AC8 LEU A 555 ? GLN A 567 ? LEU A 555 GLN A 567 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 162 SG  ? ? ? 1_555 A CYS 171 SG ? ? A CYS 162 A CYS 171 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1 covale one ? A ASN 163 ND2 ? ? ? 1_555 B NAG .   C1 ? ? A ASN 163 A NAG 701 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale2 covale one ? A ASN 179 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 179 A NAG 702 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale3 covale one ? A ASN 190 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 190 A NAG 703 1_555 ? ? ? ? ? ? ? 1.453 ? N-Glycosylation 
metalc1 metalc ?   ? A GLY 56  O   ? ? ? 1_555 H NA  .   NA ? ? A GLY 56  A NA  707 1_555 ? ? ? ? ? ? ? 2.203 ? ?               
metalc2 metalc ?   ? A VAL 59  O   ? ? ? 1_555 H NA  .   NA ? ? A VAL 59  A NA  707 1_555 ? ? ? ? ? ? ? 2.054 ? ?               
metalc3 metalc ?   ? A ASP 401 OD1 ? ? ? 1_555 H NA  .   NA ? ? A ASP 401 A NA  707 1_555 ? ? ? ? ? ? ? 2.398 ? ?               
metalc4 metalc ?   ? A SER 402 OG  ? ? ? 1_555 H NA  .   NA ? ? A SER 402 A NA  707 1_555 ? ? ? ? ? ? ? 2.190 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 O   ? A GLY 56  ? A GLY 56  ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 O   ? A VAL 59  ? A VAL 59  ? 1_555 103.9 ? 
2 O   ? A GLY 56  ? A GLY 56  ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 80.2  ? 
3 O   ? A VAL 59  ? A VAL 59  ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 122.8 ? 
4 O   ? A GLY 56  ? A GLY 56  ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 OG  ? A SER 402 ? A SER 402 ? 1_555 129.5 ? 
5 O   ? A VAL 59  ? A VAL 59  ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 OG  ? A SER 402 ? A SER 402 ? 1_555 120.7 ? 
6 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 NA ? H NA . ? A NA 707 ? 1_555 OG  ? A SER 402 ? A SER 402 ? 1_555 93.2  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG B .   ? ASN A 163 ? NAG A 701 ? 1_555 ASN A 163 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG C .   ? ASN A 179 ? NAG A 702 ? 1_555 ASN A 179 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG D .   ? ASN A 190 ? NAG A 703 ? 1_555 ASN A 190 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 CYS A 162 ? CYS A 171 ? CYS A 162 ? 1_555 CYS A 171 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 531 ? TYR A 532 ? THR A 531 TYR A 532 
AA1 2 TYR A 536 ? VAL A 537 ? TYR A 536 VAL A 537 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    532 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     532 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    536 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     536 
# 
_pdbx_entry_details.entry_id                   9JD6 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 90  ? ? -130.74 -31.05 
2 1 TYR A 323 ? ? -94.35  31.18  
3 1 ILE A 482 ? ? -124.14 -59.06 
4 1 VAL A 510 ? ? -124.18 -51.62 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JD6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_reconstruction.entry_id                    9JD6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.06 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               189468 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of human Taurine Transporter with Piperidine-4-sulfonate' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JD6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9JD6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277.15 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JD6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A THR 3   ? A THR 3   
4  1 Y 1 A LYS 4   ? A LYS 4   
5  1 Y 1 A GLU 5   ? A GLU 5   
6  1 Y 1 A LYS 6   ? A LYS 6   
7  1 Y 1 A LEU 7   ? A LEU 7   
8  1 Y 1 A GLN 8   ? A GLN 8   
9  1 Y 1 A CYS 9   ? A CYS 9   
10 1 Y 1 A LEU 10  ? A LEU 10  
11 1 Y 1 A LYS 11  ? A LYS 11  
12 1 Y 1 A ASP 12  ? A ASP 12  
13 1 Y 1 A PHE 13  ? A PHE 13  
14 1 Y 1 A HIS 14  ? A HIS 14  
15 1 Y 1 A LYS 15  ? A LYS 15  
16 1 Y 1 A ASP 16  ? A ASP 16  
17 1 Y 1 A ILE 17  ? A ILE 17  
18 1 Y 1 A LEU 18  ? A LEU 18  
19 1 Y 1 A LYS 19  ? A LYS 19  
20 1 Y 1 A PRO 20  ? A PRO 20  
21 1 Y 1 A SER 21  ? A SER 21  
22 1 Y 1 A PRO 22  ? A PRO 22  
23 1 Y 1 A GLY 23  ? A GLY 23  
24 1 Y 1 A LYS 24  ? A LYS 24  
25 1 Y 1 A SER 25  ? A SER 25  
26 1 Y 1 A PRO 26  ? A PRO 26  
27 1 Y 1 A GLY 27  ? A GLY 27  
28 1 Y 1 A THR 28  ? A THR 28  
29 1 Y 1 A ARG 29  ? A ARG 29  
30 1 Y 1 A PRO 30  ? A PRO 30  
31 1 Y 1 A GLU 31  ? A GLU 31  
32 1 Y 1 A ASP 32  ? A ASP 32  
33 1 Y 1 A GLU 33  ? A GLU 33  
34 1 Y 1 A ALA 34  ? A ALA 34  
35 1 Y 1 A GLU 35  ? A GLU 35  
36 1 Y 1 A GLY 36  ? A GLY 36  
37 1 Y 1 A LYS 37  ? A LYS 37  
38 1 Y 1 A PRO 38  ? A PRO 38  
39 1 Y 1 A PRO 39  ? A PRO 39  
40 1 Y 1 A GLN 40  ? A GLN 40  
41 1 Y 1 A LYS 180 ? A LYS 180 
42 1 Y 1 A SER 181 ? A SER 181 
43 1 Y 1 A VAL 182 ? A VAL 182 
44 1 Y 1 A TRP 183 ? A TRP 183 
45 1 Y 1 A ILE 184 ? A ILE 184 
46 1 Y 1 A THR 185 ? A THR 185 
47 1 Y 1 A ILE 186 ? A ILE 186 
48 1 Y 1 A SER 187 ? A SER 187 
49 1 Y 1 A SER 188 ? A SER 188 
50 1 Y 1 A THR 568 ? A THR 568 
51 1 Y 1 A GLU 569 ? A GLU 569 
52 1 Y 1 A GLY 570 ? A GLY 570 
53 1 Y 1 A PRO 571 ? A PRO 571 
54 1 Y 1 A PHE 572 ? A PHE 572 
55 1 Y 1 A LEU 573 ? A LEU 573 
56 1 Y 1 A VAL 574 ? A VAL 574 
57 1 Y 1 A ARG 575 ? A ARG 575 
58 1 Y 1 A VAL 576 ? A VAL 576 
59 1 Y 1 A LYS 577 ? A LYS 577 
60 1 Y 1 A TYR 578 ? A TYR 578 
61 1 Y 1 A LEU 579 ? A LEU 579 
62 1 Y 1 A LEU 580 ? A LEU 580 
63 1 Y 1 A THR 581 ? A THR 581 
64 1 Y 1 A PRO 582 ? A PRO 582 
65 1 Y 1 A SER 583 ? A SER 583 
66 1 Y 1 A ARG 584 ? A ARG 584 
67 1 Y 1 A LEU 585 ? A LEU 585 
68 1 Y 1 A GLU 586 ? A GLU 586 
69 1 Y 1 A GLU 587 ? A GLU 587 
70 1 Y 1 A GLU 588 ? A GLU 588 
71 1 Y 1 A LEU 589 ? A LEU 589 
72 1 Y 1 A ARG 590 ? A ARG 590 
73 1 Y 1 A ARG 591 ? A ARG 591 
74 1 Y 1 A ARG 592 ? A ARG 592 
75 1 Y 1 A THR 593 ? A THR 593 
76 1 Y 1 A GLU 594 ? A GLU 594 
77 1 Y 1 A PRO 595 ? A PRO 595 
78 1 Y 1 A GLY 596 ? A GLY 596 
79 1 Y 1 A LEU 597 ? A LEU 597 
80 1 Y 1 A ARG 598 ? A ARG 598 
81 1 Y 1 A SER 599 ? A SER 599 
82 1 Y 1 A ARG 600 ? A ARG 600 
83 1 Y 1 A LEU 601 ? A LEU 601 
84 1 Y 1 A GLU 602 ? A GLU 602 
85 1 Y 1 A VAL 603 ? A VAL 603 
86 1 Y 1 A LEU 604 ? A LEU 604 
87 1 Y 1 A PHE 605 ? A PHE 605 
88 1 Y 1 A GLN 606 ? A GLN 606 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1EBD C01  C  N N 1   
A1EBD C02  C  N N 2   
A1EBD C04  C  N N 3   
A1EBD C05  C  N N 4   
A1EBD C06  C  N N 5   
A1EBD N03  N  N N 6   
A1EBD O08  O  N N 7   
A1EBD O09  O  N N 8   
A1EBD O10  O  N N 9   
A1EBD S07  S  N N 10  
A1EBD H1   H  N N 11  
A1EBD H2   H  N N 12  
A1EBD H3   H  N N 13  
A1EBD H4   H  N N 14  
A1EBD H5   H  N N 15  
A1EBD H6   H  N N 16  
A1EBD H7   H  N N 17  
A1EBD H8   H  N N 18  
A1EBD H9   H  N N 19  
A1EBD H10  H  N N 20  
A1EBD H11  H  N N 21  
ALA   N    N  N N 22  
ALA   CA   C  N S 23  
ALA   C    C  N N 24  
ALA   O    O  N N 25  
ALA   CB   C  N N 26  
ALA   OXT  O  N N 27  
ALA   H    H  N N 28  
ALA   H2   H  N N 29  
ALA   HA   H  N N 30  
ALA   HB1  H  N N 31  
ALA   HB2  H  N N 32  
ALA   HB3  H  N N 33  
ALA   HXT  H  N N 34  
ARG   N    N  N N 35  
ARG   CA   C  N S 36  
ARG   C    C  N N 37  
ARG   O    O  N N 38  
ARG   CB   C  N N 39  
ARG   CG   C  N N 40  
ARG   CD   C  N N 41  
ARG   NE   N  N N 42  
ARG   CZ   C  N N 43  
ARG   NH1  N  N N 44  
ARG   NH2  N  N N 45  
ARG   OXT  O  N N 46  
ARG   H    H  N N 47  
ARG   H2   H  N N 48  
ARG   HA   H  N N 49  
ARG   HB2  H  N N 50  
ARG   HB3  H  N N 51  
ARG   HG2  H  N N 52  
ARG   HG3  H  N N 53  
ARG   HD2  H  N N 54  
ARG   HD3  H  N N 55  
ARG   HE   H  N N 56  
ARG   HH11 H  N N 57  
ARG   HH12 H  N N 58  
ARG   HH21 H  N N 59  
ARG   HH22 H  N N 60  
ARG   HXT  H  N N 61  
ASN   N    N  N N 62  
ASN   CA   C  N S 63  
ASN   C    C  N N 64  
ASN   O    O  N N 65  
ASN   CB   C  N N 66  
ASN   CG   C  N N 67  
ASN   OD1  O  N N 68  
ASN   ND2  N  N N 69  
ASN   OXT  O  N N 70  
ASN   H    H  N N 71  
ASN   H2   H  N N 72  
ASN   HA   H  N N 73  
ASN   HB2  H  N N 74  
ASN   HB3  H  N N 75  
ASN   HD21 H  N N 76  
ASN   HD22 H  N N 77  
ASN   HXT  H  N N 78  
ASP   N    N  N N 79  
ASP   CA   C  N S 80  
ASP   C    C  N N 81  
ASP   O    O  N N 82  
ASP   CB   C  N N 83  
ASP   CG   C  N N 84  
ASP   OD1  O  N N 85  
ASP   OD2  O  N N 86  
ASP   OXT  O  N N 87  
ASP   H    H  N N 88  
ASP   H2   H  N N 89  
ASP   HA   H  N N 90  
ASP   HB2  H  N N 91  
ASP   HB3  H  N N 92  
ASP   HD2  H  N N 93  
ASP   HXT  H  N N 94  
CL    CL   CL N N 95  
CYS   N    N  N N 96  
CYS   CA   C  N R 97  
CYS   C    C  N N 98  
CYS   O    O  N N 99  
CYS   CB   C  N N 100 
CYS   SG   S  N N 101 
CYS   OXT  O  N N 102 
CYS   H    H  N N 103 
CYS   H2   H  N N 104 
CYS   HA   H  N N 105 
CYS   HB2  H  N N 106 
CYS   HB3  H  N N 107 
CYS   HG   H  N N 108 
CYS   HXT  H  N N 109 
GLN   N    N  N N 110 
GLN   CA   C  N S 111 
GLN   C    C  N N 112 
GLN   O    O  N N 113 
GLN   CB   C  N N 114 
GLN   CG   C  N N 115 
GLN   CD   C  N N 116 
GLN   OE1  O  N N 117 
GLN   NE2  N  N N 118 
GLN   OXT  O  N N 119 
GLN   H    H  N N 120 
GLN   H2   H  N N 121 
GLN   HA   H  N N 122 
GLN   HB2  H  N N 123 
GLN   HB3  H  N N 124 
GLN   HG2  H  N N 125 
GLN   HG3  H  N N 126 
GLN   HE21 H  N N 127 
GLN   HE22 H  N N 128 
GLN   HXT  H  N N 129 
GLU   N    N  N N 130 
GLU   CA   C  N S 131 
GLU   C    C  N N 132 
GLU   O    O  N N 133 
GLU   CB   C  N N 134 
GLU   CG   C  N N 135 
GLU   CD   C  N N 136 
GLU   OE1  O  N N 137 
GLU   OE2  O  N N 138 
GLU   OXT  O  N N 139 
GLU   H    H  N N 140 
GLU   H2   H  N N 141 
GLU   HA   H  N N 142 
GLU   HB2  H  N N 143 
GLU   HB3  H  N N 144 
GLU   HG2  H  N N 145 
GLU   HG3  H  N N 146 
GLU   HE2  H  N N 147 
GLU   HXT  H  N N 148 
GLY   N    N  N N 149 
GLY   CA   C  N N 150 
GLY   C    C  N N 151 
GLY   O    O  N N 152 
GLY   OXT  O  N N 153 
GLY   H    H  N N 154 
GLY   H2   H  N N 155 
GLY   HA2  H  N N 156 
GLY   HA3  H  N N 157 
GLY   HXT  H  N N 158 
HIS   N    N  N N 159 
HIS   CA   C  N S 160 
HIS   C    C  N N 161 
HIS   O    O  N N 162 
HIS   CB   C  N N 163 
HIS   CG   C  Y N 164 
HIS   ND1  N  Y N 165 
HIS   CD2  C  Y N 166 
HIS   CE1  C  Y N 167 
HIS   NE2  N  Y N 168 
HIS   OXT  O  N N 169 
HIS   H    H  N N 170 
HIS   H2   H  N N 171 
HIS   HA   H  N N 172 
HIS   HB2  H  N N 173 
HIS   HB3  H  N N 174 
HIS   HD1  H  N N 175 
HIS   HD2  H  N N 176 
HIS   HE1  H  N N 177 
HIS   HE2  H  N N 178 
HIS   HXT  H  N N 179 
ILE   N    N  N N 180 
ILE   CA   C  N S 181 
ILE   C    C  N N 182 
ILE   O    O  N N 183 
ILE   CB   C  N S 184 
ILE   CG1  C  N N 185 
ILE   CG2  C  N N 186 
ILE   CD1  C  N N 187 
ILE   OXT  O  N N 188 
ILE   H    H  N N 189 
ILE   H2   H  N N 190 
ILE   HA   H  N N 191 
ILE   HB   H  N N 192 
ILE   HG12 H  N N 193 
ILE   HG13 H  N N 194 
ILE   HG21 H  N N 195 
ILE   HG22 H  N N 196 
ILE   HG23 H  N N 197 
ILE   HD11 H  N N 198 
ILE   HD12 H  N N 199 
ILE   HD13 H  N N 200 
ILE   HXT  H  N N 201 
LEU   N    N  N N 202 
LEU   CA   C  N S 203 
LEU   C    C  N N 204 
LEU   O    O  N N 205 
LEU   CB   C  N N 206 
LEU   CG   C  N N 207 
LEU   CD1  C  N N 208 
LEU   CD2  C  N N 209 
LEU   OXT  O  N N 210 
LEU   H    H  N N 211 
LEU   H2   H  N N 212 
LEU   HA   H  N N 213 
LEU   HB2  H  N N 214 
LEU   HB3  H  N N 215 
LEU   HG   H  N N 216 
LEU   HD11 H  N N 217 
LEU   HD12 H  N N 218 
LEU   HD13 H  N N 219 
LEU   HD21 H  N N 220 
LEU   HD22 H  N N 221 
LEU   HD23 H  N N 222 
LEU   HXT  H  N N 223 
LYS   N    N  N N 224 
LYS   CA   C  N S 225 
LYS   C    C  N N 226 
LYS   O    O  N N 227 
LYS   CB   C  N N 228 
LYS   CG   C  N N 229 
LYS   CD   C  N N 230 
LYS   CE   C  N N 231 
LYS   NZ   N  N N 232 
LYS   OXT  O  N N 233 
LYS   H    H  N N 234 
LYS   H2   H  N N 235 
LYS   HA   H  N N 236 
LYS   HB2  H  N N 237 
LYS   HB3  H  N N 238 
LYS   HG2  H  N N 239 
LYS   HG3  H  N N 240 
LYS   HD2  H  N N 241 
LYS   HD3  H  N N 242 
LYS   HE2  H  N N 243 
LYS   HE3  H  N N 244 
LYS   HZ1  H  N N 245 
LYS   HZ2  H  N N 246 
LYS   HZ3  H  N N 247 
LYS   HXT  H  N N 248 
MET   N    N  N N 249 
MET   CA   C  N S 250 
MET   C    C  N N 251 
MET   O    O  N N 252 
MET   CB   C  N N 253 
MET   CG   C  N N 254 
MET   SD   S  N N 255 
MET   CE   C  N N 256 
MET   OXT  O  N N 257 
MET   H    H  N N 258 
MET   H2   H  N N 259 
MET   HA   H  N N 260 
MET   HB2  H  N N 261 
MET   HB3  H  N N 262 
MET   HG2  H  N N 263 
MET   HG3  H  N N 264 
MET   HE1  H  N N 265 
MET   HE2  H  N N 266 
MET   HE3  H  N N 267 
MET   HXT  H  N N 268 
NA    NA   NA N N 269 
NAG   C1   C  N R 270 
NAG   C2   C  N R 271 
NAG   C3   C  N R 272 
NAG   C4   C  N S 273 
NAG   C5   C  N R 274 
NAG   C6   C  N N 275 
NAG   C7   C  N N 276 
NAG   C8   C  N N 277 
NAG   N2   N  N N 278 
NAG   O1   O  N N 279 
NAG   O3   O  N N 280 
NAG   O4   O  N N 281 
NAG   O5   O  N N 282 
NAG   O6   O  N N 283 
NAG   O7   O  N N 284 
NAG   H1   H  N N 285 
NAG   H2   H  N N 286 
NAG   H3   H  N N 287 
NAG   H4   H  N N 288 
NAG   H5   H  N N 289 
NAG   H61  H  N N 290 
NAG   H62  H  N N 291 
NAG   H81  H  N N 292 
NAG   H82  H  N N 293 
NAG   H83  H  N N 294 
NAG   HN2  H  N N 295 
NAG   HO1  H  N N 296 
NAG   HO3  H  N N 297 
NAG   HO4  H  N N 298 
NAG   HO6  H  N N 299 
PHE   N    N  N N 300 
PHE   CA   C  N S 301 
PHE   C    C  N N 302 
PHE   O    O  N N 303 
PHE   CB   C  N N 304 
PHE   CG   C  Y N 305 
PHE   CD1  C  Y N 306 
PHE   CD2  C  Y N 307 
PHE   CE1  C  Y N 308 
PHE   CE2  C  Y N 309 
PHE   CZ   C  Y N 310 
PHE   OXT  O  N N 311 
PHE   H    H  N N 312 
PHE   H2   H  N N 313 
PHE   HA   H  N N 314 
PHE   HB2  H  N N 315 
PHE   HB3  H  N N 316 
PHE   HD1  H  N N 317 
PHE   HD2  H  N N 318 
PHE   HE1  H  N N 319 
PHE   HE2  H  N N 320 
PHE   HZ   H  N N 321 
PHE   HXT  H  N N 322 
PRO   N    N  N N 323 
PRO   CA   C  N S 324 
PRO   C    C  N N 325 
PRO   O    O  N N 326 
PRO   CB   C  N N 327 
PRO   CG   C  N N 328 
PRO   CD   C  N N 329 
PRO   OXT  O  N N 330 
PRO   H    H  N N 331 
PRO   HA   H  N N 332 
PRO   HB2  H  N N 333 
PRO   HB3  H  N N 334 
PRO   HG2  H  N N 335 
PRO   HG3  H  N N 336 
PRO   HD2  H  N N 337 
PRO   HD3  H  N N 338 
PRO   HXT  H  N N 339 
SER   N    N  N N 340 
SER   CA   C  N S 341 
SER   C    C  N N 342 
SER   O    O  N N 343 
SER   CB   C  N N 344 
SER   OG   O  N N 345 
SER   OXT  O  N N 346 
SER   H    H  N N 347 
SER   H2   H  N N 348 
SER   HA   H  N N 349 
SER   HB2  H  N N 350 
SER   HB3  H  N N 351 
SER   HG   H  N N 352 
SER   HXT  H  N N 353 
THR   N    N  N N 354 
THR   CA   C  N S 355 
THR   C    C  N N 356 
THR   O    O  N N 357 
THR   CB   C  N R 358 
THR   OG1  O  N N 359 
THR   CG2  C  N N 360 
THR   OXT  O  N N 361 
THR   H    H  N N 362 
THR   H2   H  N N 363 
THR   HA   H  N N 364 
THR   HB   H  N N 365 
THR   HG1  H  N N 366 
THR   HG21 H  N N 367 
THR   HG22 H  N N 368 
THR   HG23 H  N N 369 
THR   HXT  H  N N 370 
TRP   N    N  N N 371 
TRP   CA   C  N S 372 
TRP   C    C  N N 373 
TRP   O    O  N N 374 
TRP   CB   C  N N 375 
TRP   CG   C  Y N 376 
TRP   CD1  C  Y N 377 
TRP   CD2  C  Y N 378 
TRP   NE1  N  Y N 379 
TRP   CE2  C  Y N 380 
TRP   CE3  C  Y N 381 
TRP   CZ2  C  Y N 382 
TRP   CZ3  C  Y N 383 
TRP   CH2  C  Y N 384 
TRP   OXT  O  N N 385 
TRP   H    H  N N 386 
TRP   H2   H  N N 387 
TRP   HA   H  N N 388 
TRP   HB2  H  N N 389 
TRP   HB3  H  N N 390 
TRP   HD1  H  N N 391 
TRP   HE1  H  N N 392 
TRP   HE3  H  N N 393 
TRP   HZ2  H  N N 394 
TRP   HZ3  H  N N 395 
TRP   HH2  H  N N 396 
TRP   HXT  H  N N 397 
TYR   N    N  N N 398 
TYR   CA   C  N S 399 
TYR   C    C  N N 400 
TYR   O    O  N N 401 
TYR   CB   C  N N 402 
TYR   CG   C  Y N 403 
TYR   CD1  C  Y N 404 
TYR   CD2  C  Y N 405 
TYR   CE1  C  Y N 406 
TYR   CE2  C  Y N 407 
TYR   CZ   C  Y N 408 
TYR   OH   O  N N 409 
TYR   OXT  O  N N 410 
TYR   H    H  N N 411 
TYR   H2   H  N N 412 
TYR   HA   H  N N 413 
TYR   HB2  H  N N 414 
TYR   HB3  H  N N 415 
TYR   HD1  H  N N 416 
TYR   HD2  H  N N 417 
TYR   HE1  H  N N 418 
TYR   HE2  H  N N 419 
TYR   HH   H  N N 420 
TYR   HXT  H  N N 421 
VAL   N    N  N N 422 
VAL   CA   C  N S 423 
VAL   C    C  N N 424 
VAL   O    O  N N 425 
VAL   CB   C  N N 426 
VAL   CG1  C  N N 427 
VAL   CG2  C  N N 428 
VAL   OXT  O  N N 429 
VAL   H    H  N N 430 
VAL   H2   H  N N 431 
VAL   HA   H  N N 432 
VAL   HB   H  N N 433 
VAL   HG11 H  N N 434 
VAL   HG12 H  N N 435 
VAL   HG13 H  N N 436 
VAL   HG21 H  N N 437 
VAL   HG22 H  N N 438 
VAL   HG23 H  N N 439 
VAL   HXT  H  N N 440 
Y01   CAA  C  N N 441 
Y01   CBA  C  N N 442 
Y01   CAB  C  N N 443 
Y01   CAN  C  N N 444 
Y01   CAJ  C  N N 445 
Y01   CAO  C  N N 446 
Y01   CBB  C  N R 447 
Y01   CAC  C  N N 448 
Y01   CBE  C  N R 449 
Y01   CAP  C  N N 450 
Y01   CAQ  C  N N 451 
Y01   CBG  C  N S 452 
Y01   CBI  C  N R 453 
Y01   CAE  C  N N 454 
Y01   CAU  C  N N 455 
Y01   CAS  C  N N 456 
Y01   CBF  C  N S 457 
Y01   CBD  C  N S 458 
Y01   CAK  C  N N 459 
Y01   CAI  C  N N 460 
Y01   CAZ  C  N N 461 
Y01   CAV  C  N N 462 
Y01   CBH  C  N R 463 
Y01   CAD  C  N N 464 
Y01   CAT  C  N N 465 
Y01   CAR  C  N N 466 
Y01   CBC  C  N S 467 
Y01   OAW  O  N N 468 
Y01   CAY  C  N N 469 
Y01   OAG  O  N N 470 
Y01   CAM  C  N N 471 
Y01   CAL  C  N N 472 
Y01   CAX  C  N N 473 
Y01   OAH  O  N N 474 
Y01   OAF  O  N N 475 
Y01   HAA1 H  N N 476 
Y01   HAA2 H  N N 477 
Y01   HAA3 H  N N 478 
Y01   HBA  H  N N 479 
Y01   HAB1 H  N N 480 
Y01   HAB2 H  N N 481 
Y01   HAB3 H  N N 482 
Y01   HAN1 H  N N 483 
Y01   HAN2 H  N N 484 
Y01   HAJ1 H  N N 485 
Y01   HAJ2 H  N N 486 
Y01   HAO1 H  N N 487 
Y01   HAO2 H  N N 488 
Y01   HBB  H  N N 489 
Y01   HAC1 H  N N 490 
Y01   HAC2 H  N N 491 
Y01   HAC3 H  N N 492 
Y01   HBE  H  N N 493 
Y01   HAP1 H  N N 494 
Y01   HAP2 H  N N 495 
Y01   HAQ1 H  N N 496 
Y01   HAQ2 H  N N 497 
Y01   HBG  H  N N 498 
Y01   HBD  H  N N 499 
Y01   HAE1 H  N N 500 
Y01   HAE2 H  N N 501 
Y01   HAE3 H  N N 502 
Y01   HAU1 H  N N 503 
Y01   HAU2 H  N N 504 
Y01   HAS1 H  N N 505 
Y01   HAS2 H  N N 506 
Y01   HBF  H  N N 507 
Y01   HAK1 H  N N 508 
Y01   HAK2 H  N N 509 
Y01   HAI  H  N N 510 
Y01   HAV1 H  N N 511 
Y01   HAV2 H  N N 512 
Y01   HBC  H  N N 513 
Y01   HAD1 H  N N 514 
Y01   HAD2 H  N N 515 
Y01   HAD3 H  N N 516 
Y01   HAT1 H  N N 517 
Y01   HAT2 H  N N 518 
Y01   HAR1 H  N N 519 
Y01   HAR2 H  N N 520 
Y01   HAM1 H  N N 521 
Y01   HAM2 H  N N 522 
Y01   HAL1 H  N N 523 
Y01   HAL2 H  N N 524 
Y01   HAH  H  N N 525 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1EBD O09 S07  doub N N 1   
A1EBD O08 S07  doub N N 2   
A1EBD S07 O10  sing N N 3   
A1EBD S07 C06  sing N N 4   
A1EBD C06 C01  sing N N 5   
A1EBD C06 C05  sing N N 6   
A1EBD C01 C02  sing N N 7   
A1EBD C05 C04  sing N N 8   
A1EBD C02 N03  sing N N 9   
A1EBD C04 N03  sing N N 10  
A1EBD C01 H1   sing N N 11  
A1EBD C01 H2   sing N N 12  
A1EBD C02 H3   sing N N 13  
A1EBD C02 H4   sing N N 14  
A1EBD C04 H5   sing N N 15  
A1EBD C04 H6   sing N N 16  
A1EBD C05 H7   sing N N 17  
A1EBD C05 H8   sing N N 18  
A1EBD C06 H9   sing N N 19  
A1EBD N03 H10  sing N N 20  
A1EBD O10 H11  sing N N 21  
ALA   N   CA   sing N N 22  
ALA   N   H    sing N N 23  
ALA   N   H2   sing N N 24  
ALA   CA  C    sing N N 25  
ALA   CA  CB   sing N N 26  
ALA   CA  HA   sing N N 27  
ALA   C   O    doub N N 28  
ALA   C   OXT  sing N N 29  
ALA   CB  HB1  sing N N 30  
ALA   CB  HB2  sing N N 31  
ALA   CB  HB3  sing N N 32  
ALA   OXT HXT  sing N N 33  
ARG   N   CA   sing N N 34  
ARG   N   H    sing N N 35  
ARG   N   H2   sing N N 36  
ARG   CA  C    sing N N 37  
ARG   CA  CB   sing N N 38  
ARG   CA  HA   sing N N 39  
ARG   C   O    doub N N 40  
ARG   C   OXT  sing N N 41  
ARG   CB  CG   sing N N 42  
ARG   CB  HB2  sing N N 43  
ARG   CB  HB3  sing N N 44  
ARG   CG  CD   sing N N 45  
ARG   CG  HG2  sing N N 46  
ARG   CG  HG3  sing N N 47  
ARG   CD  NE   sing N N 48  
ARG   CD  HD2  sing N N 49  
ARG   CD  HD3  sing N N 50  
ARG   NE  CZ   sing N N 51  
ARG   NE  HE   sing N N 52  
ARG   CZ  NH1  sing N N 53  
ARG   CZ  NH2  doub N N 54  
ARG   NH1 HH11 sing N N 55  
ARG   NH1 HH12 sing N N 56  
ARG   NH2 HH21 sing N N 57  
ARG   NH2 HH22 sing N N 58  
ARG   OXT HXT  sing N N 59  
ASN   N   CA   sing N N 60  
ASN   N   H    sing N N 61  
ASN   N   H2   sing N N 62  
ASN   CA  C    sing N N 63  
ASN   CA  CB   sing N N 64  
ASN   CA  HA   sing N N 65  
ASN   C   O    doub N N 66  
ASN   C   OXT  sing N N 67  
ASN   CB  CG   sing N N 68  
ASN   CB  HB2  sing N N 69  
ASN   CB  HB3  sing N N 70  
ASN   CG  OD1  doub N N 71  
ASN   CG  ND2  sing N N 72  
ASN   ND2 HD21 sing N N 73  
ASN   ND2 HD22 sing N N 74  
ASN   OXT HXT  sing N N 75  
ASP   N   CA   sing N N 76  
ASP   N   H    sing N N 77  
ASP   N   H2   sing N N 78  
ASP   CA  C    sing N N 79  
ASP   CA  CB   sing N N 80  
ASP   CA  HA   sing N N 81  
ASP   C   O    doub N N 82  
ASP   C   OXT  sing N N 83  
ASP   CB  CG   sing N N 84  
ASP   CB  HB2  sing N N 85  
ASP   CB  HB3  sing N N 86  
ASP   CG  OD1  doub N N 87  
ASP   CG  OD2  sing N N 88  
ASP   OD2 HD2  sing N N 89  
ASP   OXT HXT  sing N N 90  
CYS   N   CA   sing N N 91  
CYS   N   H    sing N N 92  
CYS   N   H2   sing N N 93  
CYS   CA  C    sing N N 94  
CYS   CA  CB   sing N N 95  
CYS   CA  HA   sing N N 96  
CYS   C   O    doub N N 97  
CYS   C   OXT  sing N N 98  
CYS   CB  SG   sing N N 99  
CYS   CB  HB2  sing N N 100 
CYS   CB  HB3  sing N N 101 
CYS   SG  HG   sing N N 102 
CYS   OXT HXT  sing N N 103 
GLN   N   CA   sing N N 104 
GLN   N   H    sing N N 105 
GLN   N   H2   sing N N 106 
GLN   CA  C    sing N N 107 
GLN   CA  CB   sing N N 108 
GLN   CA  HA   sing N N 109 
GLN   C   O    doub N N 110 
GLN   C   OXT  sing N N 111 
GLN   CB  CG   sing N N 112 
GLN   CB  HB2  sing N N 113 
GLN   CB  HB3  sing N N 114 
GLN   CG  CD   sing N N 115 
GLN   CG  HG2  sing N N 116 
GLN   CG  HG3  sing N N 117 
GLN   CD  OE1  doub N N 118 
GLN   CD  NE2  sing N N 119 
GLN   NE2 HE21 sing N N 120 
GLN   NE2 HE22 sing N N 121 
GLN   OXT HXT  sing N N 122 
GLU   N   CA   sing N N 123 
GLU   N   H    sing N N 124 
GLU   N   H2   sing N N 125 
GLU   CA  C    sing N N 126 
GLU   CA  CB   sing N N 127 
GLU   CA  HA   sing N N 128 
GLU   C   O    doub N N 129 
GLU   C   OXT  sing N N 130 
GLU   CB  CG   sing N N 131 
GLU   CB  HB2  sing N N 132 
GLU   CB  HB3  sing N N 133 
GLU   CG  CD   sing N N 134 
GLU   CG  HG2  sing N N 135 
GLU   CG  HG3  sing N N 136 
GLU   CD  OE1  doub N N 137 
GLU   CD  OE2  sing N N 138 
GLU   OE2 HE2  sing N N 139 
GLU   OXT HXT  sing N N 140 
GLY   N   CA   sing N N 141 
GLY   N   H    sing N N 142 
GLY   N   H2   sing N N 143 
GLY   CA  C    sing N N 144 
GLY   CA  HA2  sing N N 145 
GLY   CA  HA3  sing N N 146 
GLY   C   O    doub N N 147 
GLY   C   OXT  sing N N 148 
GLY   OXT HXT  sing N N 149 
HIS   N   CA   sing N N 150 
HIS   N   H    sing N N 151 
HIS   N   H2   sing N N 152 
HIS   CA  C    sing N N 153 
HIS   CA  CB   sing N N 154 
HIS   CA  HA   sing N N 155 
HIS   C   O    doub N N 156 
HIS   C   OXT  sing N N 157 
HIS   CB  CG   sing N N 158 
HIS   CB  HB2  sing N N 159 
HIS   CB  HB3  sing N N 160 
HIS   CG  ND1  sing Y N 161 
HIS   CG  CD2  doub Y N 162 
HIS   ND1 CE1  doub Y N 163 
HIS   ND1 HD1  sing N N 164 
HIS   CD2 NE2  sing Y N 165 
HIS   CD2 HD2  sing N N 166 
HIS   CE1 NE2  sing Y N 167 
HIS   CE1 HE1  sing N N 168 
HIS   NE2 HE2  sing N N 169 
HIS   OXT HXT  sing N N 170 
ILE   N   CA   sing N N 171 
ILE   N   H    sing N N 172 
ILE   N   H2   sing N N 173 
ILE   CA  C    sing N N 174 
ILE   CA  CB   sing N N 175 
ILE   CA  HA   sing N N 176 
ILE   C   O    doub N N 177 
ILE   C   OXT  sing N N 178 
ILE   CB  CG1  sing N N 179 
ILE   CB  CG2  sing N N 180 
ILE   CB  HB   sing N N 181 
ILE   CG1 CD1  sing N N 182 
ILE   CG1 HG12 sing N N 183 
ILE   CG1 HG13 sing N N 184 
ILE   CG2 HG21 sing N N 185 
ILE   CG2 HG22 sing N N 186 
ILE   CG2 HG23 sing N N 187 
ILE   CD1 HD11 sing N N 188 
ILE   CD1 HD12 sing N N 189 
ILE   CD1 HD13 sing N N 190 
ILE   OXT HXT  sing N N 191 
LEU   N   CA   sing N N 192 
LEU   N   H    sing N N 193 
LEU   N   H2   sing N N 194 
LEU   CA  C    sing N N 195 
LEU   CA  CB   sing N N 196 
LEU   CA  HA   sing N N 197 
LEU   C   O    doub N N 198 
LEU   C   OXT  sing N N 199 
LEU   CB  CG   sing N N 200 
LEU   CB  HB2  sing N N 201 
LEU   CB  HB3  sing N N 202 
LEU   CG  CD1  sing N N 203 
LEU   CG  CD2  sing N N 204 
LEU   CG  HG   sing N N 205 
LEU   CD1 HD11 sing N N 206 
LEU   CD1 HD12 sing N N 207 
LEU   CD1 HD13 sing N N 208 
LEU   CD2 HD21 sing N N 209 
LEU   CD2 HD22 sing N N 210 
LEU   CD2 HD23 sing N N 211 
LEU   OXT HXT  sing N N 212 
LYS   N   CA   sing N N 213 
LYS   N   H    sing N N 214 
LYS   N   H2   sing N N 215 
LYS   CA  C    sing N N 216 
LYS   CA  CB   sing N N 217 
LYS   CA  HA   sing N N 218 
LYS   C   O    doub N N 219 
LYS   C   OXT  sing N N 220 
LYS   CB  CG   sing N N 221 
LYS   CB  HB2  sing N N 222 
LYS   CB  HB3  sing N N 223 
LYS   CG  CD   sing N N 224 
LYS   CG  HG2  sing N N 225 
LYS   CG  HG3  sing N N 226 
LYS   CD  CE   sing N N 227 
LYS   CD  HD2  sing N N 228 
LYS   CD  HD3  sing N N 229 
LYS   CE  NZ   sing N N 230 
LYS   CE  HE2  sing N N 231 
LYS   CE  HE3  sing N N 232 
LYS   NZ  HZ1  sing N N 233 
LYS   NZ  HZ2  sing N N 234 
LYS   NZ  HZ3  sing N N 235 
LYS   OXT HXT  sing N N 236 
MET   N   CA   sing N N 237 
MET   N   H    sing N N 238 
MET   N   H2   sing N N 239 
MET   CA  C    sing N N 240 
MET   CA  CB   sing N N 241 
MET   CA  HA   sing N N 242 
MET   C   O    doub N N 243 
MET   C   OXT  sing N N 244 
MET   CB  CG   sing N N 245 
MET   CB  HB2  sing N N 246 
MET   CB  HB3  sing N N 247 
MET   CG  SD   sing N N 248 
MET   CG  HG2  sing N N 249 
MET   CG  HG3  sing N N 250 
MET   SD  CE   sing N N 251 
MET   CE  HE1  sing N N 252 
MET   CE  HE2  sing N N 253 
MET   CE  HE3  sing N N 254 
MET   OXT HXT  sing N N 255 
NAG   C1  C2   sing N N 256 
NAG   C1  O1   sing N N 257 
NAG   C1  O5   sing N N 258 
NAG   C1  H1   sing N N 259 
NAG   C2  C3   sing N N 260 
NAG   C2  N2   sing N N 261 
NAG   C2  H2   sing N N 262 
NAG   C3  C4   sing N N 263 
NAG   C3  O3   sing N N 264 
NAG   C3  H3   sing N N 265 
NAG   C4  C5   sing N N 266 
NAG   C4  O4   sing N N 267 
NAG   C4  H4   sing N N 268 
NAG   C5  C6   sing N N 269 
NAG   C5  O5   sing N N 270 
NAG   C5  H5   sing N N 271 
NAG   C6  O6   sing N N 272 
NAG   C6  H61  sing N N 273 
NAG   C6  H62  sing N N 274 
NAG   C7  C8   sing N N 275 
NAG   C7  N2   sing N N 276 
NAG   C7  O7   doub N N 277 
NAG   C8  H81  sing N N 278 
NAG   C8  H82  sing N N 279 
NAG   C8  H83  sing N N 280 
NAG   N2  HN2  sing N N 281 
NAG   O1  HO1  sing N N 282 
NAG   O3  HO3  sing N N 283 
NAG   O4  HO4  sing N N 284 
NAG   O6  HO6  sing N N 285 
PHE   N   CA   sing N N 286 
PHE   N   H    sing N N 287 
PHE   N   H2   sing N N 288 
PHE   CA  C    sing N N 289 
PHE   CA  CB   sing N N 290 
PHE   CA  HA   sing N N 291 
PHE   C   O    doub N N 292 
PHE   C   OXT  sing N N 293 
PHE   CB  CG   sing N N 294 
PHE   CB  HB2  sing N N 295 
PHE   CB  HB3  sing N N 296 
PHE   CG  CD1  doub Y N 297 
PHE   CG  CD2  sing Y N 298 
PHE   CD1 CE1  sing Y N 299 
PHE   CD1 HD1  sing N N 300 
PHE   CD2 CE2  doub Y N 301 
PHE   CD2 HD2  sing N N 302 
PHE   CE1 CZ   doub Y N 303 
PHE   CE1 HE1  sing N N 304 
PHE   CE2 CZ   sing Y N 305 
PHE   CE2 HE2  sing N N 306 
PHE   CZ  HZ   sing N N 307 
PHE   OXT HXT  sing N N 308 
PRO   N   CA   sing N N 309 
PRO   N   CD   sing N N 310 
PRO   N   H    sing N N 311 
PRO   CA  C    sing N N 312 
PRO   CA  CB   sing N N 313 
PRO   CA  HA   sing N N 314 
PRO   C   O    doub N N 315 
PRO   C   OXT  sing N N 316 
PRO   CB  CG   sing N N 317 
PRO   CB  HB2  sing N N 318 
PRO   CB  HB3  sing N N 319 
PRO   CG  CD   sing N N 320 
PRO   CG  HG2  sing N N 321 
PRO   CG  HG3  sing N N 322 
PRO   CD  HD2  sing N N 323 
PRO   CD  HD3  sing N N 324 
PRO   OXT HXT  sing N N 325 
SER   N   CA   sing N N 326 
SER   N   H    sing N N 327 
SER   N   H2   sing N N 328 
SER   CA  C    sing N N 329 
SER   CA  CB   sing N N 330 
SER   CA  HA   sing N N 331 
SER   C   O    doub N N 332 
SER   C   OXT  sing N N 333 
SER   CB  OG   sing N N 334 
SER   CB  HB2  sing N N 335 
SER   CB  HB3  sing N N 336 
SER   OG  HG   sing N N 337 
SER   OXT HXT  sing N N 338 
THR   N   CA   sing N N 339 
THR   N   H    sing N N 340 
THR   N   H2   sing N N 341 
THR   CA  C    sing N N 342 
THR   CA  CB   sing N N 343 
THR   CA  HA   sing N N 344 
THR   C   O    doub N N 345 
THR   C   OXT  sing N N 346 
THR   CB  OG1  sing N N 347 
THR   CB  CG2  sing N N 348 
THR   CB  HB   sing N N 349 
THR   OG1 HG1  sing N N 350 
THR   CG2 HG21 sing N N 351 
THR   CG2 HG22 sing N N 352 
THR   CG2 HG23 sing N N 353 
THR   OXT HXT  sing N N 354 
TRP   N   CA   sing N N 355 
TRP   N   H    sing N N 356 
TRP   N   H2   sing N N 357 
TRP   CA  C    sing N N 358 
TRP   CA  CB   sing N N 359 
TRP   CA  HA   sing N N 360 
TRP   C   O    doub N N 361 
TRP   C   OXT  sing N N 362 
TRP   CB  CG   sing N N 363 
TRP   CB  HB2  sing N N 364 
TRP   CB  HB3  sing N N 365 
TRP   CG  CD1  doub Y N 366 
TRP   CG  CD2  sing Y N 367 
TRP   CD1 NE1  sing Y N 368 
TRP   CD1 HD1  sing N N 369 
TRP   CD2 CE2  doub Y N 370 
TRP   CD2 CE3  sing Y N 371 
TRP   NE1 CE2  sing Y N 372 
TRP   NE1 HE1  sing N N 373 
TRP   CE2 CZ2  sing Y N 374 
TRP   CE3 CZ3  doub Y N 375 
TRP   CE3 HE3  sing N N 376 
TRP   CZ2 CH2  doub Y N 377 
TRP   CZ2 HZ2  sing N N 378 
TRP   CZ3 CH2  sing Y N 379 
TRP   CZ3 HZ3  sing N N 380 
TRP   CH2 HH2  sing N N 381 
TRP   OXT HXT  sing N N 382 
TYR   N   CA   sing N N 383 
TYR   N   H    sing N N 384 
TYR   N   H2   sing N N 385 
TYR   CA  C    sing N N 386 
TYR   CA  CB   sing N N 387 
TYR   CA  HA   sing N N 388 
TYR   C   O    doub N N 389 
TYR   C   OXT  sing N N 390 
TYR   CB  CG   sing N N 391 
TYR   CB  HB2  sing N N 392 
TYR   CB  HB3  sing N N 393 
TYR   CG  CD1  doub Y N 394 
TYR   CG  CD2  sing Y N 395 
TYR   CD1 CE1  sing Y N 396 
TYR   CD1 HD1  sing N N 397 
TYR   CD2 CE2  doub Y N 398 
TYR   CD2 HD2  sing N N 399 
TYR   CE1 CZ   doub Y N 400 
TYR   CE1 HE1  sing N N 401 
TYR   CE2 CZ   sing Y N 402 
TYR   CE2 HE2  sing N N 403 
TYR   CZ  OH   sing N N 404 
TYR   OH  HH   sing N N 405 
TYR   OXT HXT  sing N N 406 
VAL   N   CA   sing N N 407 
VAL   N   H    sing N N 408 
VAL   N   H2   sing N N 409 
VAL   CA  C    sing N N 410 
VAL   CA  CB   sing N N 411 
VAL   CA  HA   sing N N 412 
VAL   C   O    doub N N 413 
VAL   C   OXT  sing N N 414 
VAL   CB  CG1  sing N N 415 
VAL   CB  CG2  sing N N 416 
VAL   CB  HB   sing N N 417 
VAL   CG1 HG11 sing N N 418 
VAL   CG1 HG12 sing N N 419 
VAL   CG1 HG13 sing N N 420 
VAL   CG2 HG21 sing N N 421 
VAL   CG2 HG22 sing N N 422 
VAL   CG2 HG23 sing N N 423 
VAL   OXT HXT  sing N N 424 
Y01   CAA CBA  sing N N 425 
Y01   CBA CAB  sing N N 426 
Y01   CBA CAN  sing N N 427 
Y01   CAN CAJ  sing N N 428 
Y01   CAJ CAO  sing N N 429 
Y01   CAO CBB  sing N N 430 
Y01   CBB CAC  sing N N 431 
Y01   CBB CBE  sing N N 432 
Y01   CBE CAP  sing N N 433 
Y01   CBE CBI  sing N N 434 
Y01   CAP CAQ  sing N N 435 
Y01   CAQ CBG  sing N N 436 
Y01   CBG CBI  sing N N 437 
Y01   CBG CBD  sing N N 438 
Y01   CBI CAE  sing N N 439 
Y01   CBI CAU  sing N N 440 
Y01   CAU CAS  sing N N 441 
Y01   CAS CBF  sing N N 442 
Y01   CBF CBD  sing N N 443 
Y01   CBF CBH  sing N N 444 
Y01   CBD CAK  sing N N 445 
Y01   CAK CAI  sing N N 446 
Y01   CAI CAZ  doub N N 447 
Y01   CAZ CAV  sing N N 448 
Y01   CAZ CBH  sing N N 449 
Y01   CAV CBC  sing N N 450 
Y01   CBH CAD  sing N N 451 
Y01   CBH CAT  sing N N 452 
Y01   CAT CAR  sing N N 453 
Y01   CAR CBC  sing N N 454 
Y01   CBC OAW  sing N N 455 
Y01   OAW CAY  sing N N 456 
Y01   CAY OAG  doub N N 457 
Y01   CAY CAM  sing N N 458 
Y01   CAM CAL  sing N N 459 
Y01   CAL CAX  sing N N 460 
Y01   CAX OAH  sing N N 461 
Y01   CAX OAF  doub N N 462 
Y01   CAA HAA1 sing N N 463 
Y01   CAA HAA2 sing N N 464 
Y01   CAA HAA3 sing N N 465 
Y01   CBA HBA  sing N N 466 
Y01   CAB HAB1 sing N N 467 
Y01   CAB HAB2 sing N N 468 
Y01   CAB HAB3 sing N N 469 
Y01   CAN HAN1 sing N N 470 
Y01   CAN HAN2 sing N N 471 
Y01   CAJ HAJ1 sing N N 472 
Y01   CAJ HAJ2 sing N N 473 
Y01   CAO HAO1 sing N N 474 
Y01   CAO HAO2 sing N N 475 
Y01   CBB HBB  sing N N 476 
Y01   CAC HAC1 sing N N 477 
Y01   CAC HAC2 sing N N 478 
Y01   CAC HAC3 sing N N 479 
Y01   CBE HBE  sing N N 480 
Y01   CAP HAP1 sing N N 481 
Y01   CAP HAP2 sing N N 482 
Y01   CAQ HAQ1 sing N N 483 
Y01   CAQ HAQ2 sing N N 484 
Y01   CBG HBG  sing N N 485 
Y01   CBD HBD  sing N N 486 
Y01   CAE HAE1 sing N N 487 
Y01   CAE HAE2 sing N N 488 
Y01   CAE HAE3 sing N N 489 
Y01   CAU HAU1 sing N N 490 
Y01   CAU HAU2 sing N N 491 
Y01   CAS HAS1 sing N N 492 
Y01   CAS HAS2 sing N N 493 
Y01   CBF HBF  sing N N 494 
Y01   CAK HAK1 sing N N 495 
Y01   CAK HAK2 sing N N 496 
Y01   CAI HAI  sing N N 497 
Y01   CAV HAV1 sing N N 498 
Y01   CAV HAV2 sing N N 499 
Y01   CBC HBC  sing N N 500 
Y01   CAD HAD1 sing N N 501 
Y01   CAD HAD2 sing N N 502 
Y01   CAD HAD3 sing N N 503 
Y01   CAT HAT1 sing N N 504 
Y01   CAT HAT2 sing N N 505 
Y01   CAR HAR1 sing N N 506 
Y01   CAR HAR2 sing N N 507 
Y01   CAM HAM1 sing N N 508 
Y01   CAM HAM2 sing N N 509 
Y01   CAL HAL1 sing N N 510 
Y01   CAL HAL2 sing N N 511 
Y01   OAH HAH  sing N N 512 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-30 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JD6 
_em_admin.last_update        2025-03-19 
_em_admin.map_release_date   2025-03-19 
_em_admin.title              
'Cryo-EM structure of human TauT in presence of Piperidine-4-sulfonate, determined in an inward-facing occluded conformation' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.19.2_4158: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32171194 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JD6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
NA 
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ARG   A 1 41  ? 77.627  110.837 108.263 1.00 118.09 ? 41  ARG   A N   1 
ATOM   2    C  CA  . ARG   A 1 41  ? 76.434  111.103 107.468 1.00 118.09 ? 41  ARG   A CA  1 
ATOM   3    C  C   . ARG   A 1 41  ? 76.557  110.492 106.077 1.00 118.09 ? 41  ARG   A C   1 
ATOM   4    O  O   . ARG   A 1 41  ? 76.040  111.037 105.102 1.00 118.09 ? 41  ARG   A O   1 
ATOM   5    C  CB  . ARG   A 1 41  ? 76.185  112.609 107.362 1.00 118.09 ? 41  ARG   A CB  1 
ATOM   6    N  N   . GLU   A 1 42  ? 77.246  109.357 105.993 1.00 114.11 ? 42  GLU   A N   1 
ATOM   7    C  CA  . GLU   A 1 42  ? 77.444  108.676 104.722 1.00 114.11 ? 42  GLU   A CA  1 
ATOM   8    C  C   . GLU   A 1 42  ? 77.708  107.204 104.996 1.00 114.11 ? 42  GLU   A C   1 
ATOM   9    O  O   . GLU   A 1 42  ? 78.268  106.837 106.032 1.00 114.11 ? 42  GLU   A O   1 
ATOM   10   C  CB  . GLU   A 1 42  ? 78.597  109.305 103.927 1.00 114.11 ? 42  GLU   A CB  1 
ATOM   11   C  CG  . GLU   A 1 42  ? 78.852  108.684 102.559 1.00 114.11 ? 42  GLU   A CG  1 
ATOM   12   C  CD  . GLU   A 1 42  ? 77.698  108.887 101.595 1.00 114.11 ? 42  GLU   A CD  1 
ATOM   13   O  OE1 . GLU   A 1 42  ? 76.943  109.868 101.762 1.00 114.11 ? 42  GLU   A OE1 1 
ATOM   14   O  OE2 . GLU   A 1 42  ? 77.547  108.065 100.668 1.00 114.11 ? 42  GLU   A OE2 1 
ATOM   15   N  N   . LYS   A 1 43  ? 77.294  106.364 104.052 1.00 110.23 ? 43  LYS   A N   1 
ATOM   16   C  CA  . LYS   A 1 43  ? 77.501  104.928 104.158 1.00 110.23 ? 43  LYS   A CA  1 
ATOM   17   C  C   . LYS   A 1 43  ? 77.634  104.360 102.752 1.00 110.23 ? 43  LYS   A C   1 
ATOM   18   O  O   . LYS   A 1 43  ? 77.217  104.977 101.770 1.00 110.23 ? 43  LYS   A O   1 
ATOM   19   C  CB  . LYS   A 1 43  ? 76.360  104.252 104.925 1.00 110.23 ? 43  LYS   A CB  1 
ATOM   20   C  CG  . LYS   A 1 43  ? 76.757  102.959 105.620 1.00 110.23 ? 43  LYS   A CG  1 
ATOM   21   C  CD  . LYS   A 1 43  ? 75.742  102.560 106.678 1.00 110.23 ? 43  LYS   A CD  1 
ATOM   22   C  CE  . LYS   A 1 43  ? 74.330  102.543 106.116 1.00 110.23 ? 43  LYS   A CE  1 
ATOM   23   N  NZ  . LYS   A 1 43  ? 73.396  101.784 106.994 1.00 110.23 ? 43  LYS   A NZ  1 
ATOM   24   N  N   . TRP   A 1 44  ? 78.230  103.173 102.671 1.00 115.38 ? 44  TRP   A N   1 
ATOM   25   C  CA  . TRP   A 1 44  ? 78.434  102.527 101.383 1.00 115.38 ? 44  TRP   A CA  1 
ATOM   26   C  C   . TRP   A 1 44  ? 77.098  102.158 100.747 1.00 115.38 ? 44  TRP   A C   1 
ATOM   27   O  O   . TRP   A 1 44  ? 76.135  101.799 101.430 1.00 115.38 ? 44  TRP   A O   1 
ATOM   28   C  CB  . TRP   A 1 44  ? 79.301  101.277 101.545 1.00 115.38 ? 44  TRP   A CB  1 
ATOM   29   N  N   . SER   A 1 45  ? 77.049  102.250 99.420  1.00 117.41 ? 45  SER   A N   1 
ATOM   30   C  CA  . SER   A 1 45  ? 75.850  101.912 98.663  1.00 117.41 ? 45  SER   A CA  1 
ATOM   31   C  C   . SER   A 1 45  ? 75.774  100.440 98.286  1.00 117.41 ? 45  SER   A C   1 
ATOM   32   O  O   . SER   A 1 45  ? 74.673  99.929  98.055  1.00 117.41 ? 45  SER   A O   1 
ATOM   33   C  CB  . SER   A 1 45  ? 75.769  102.762 97.390  1.00 117.41 ? 45  SER   A CB  1 
ATOM   34   O  OG  . SER   A 1 45  ? 76.847  102.478 96.516  1.00 117.41 ? 45  SER   A OG  1 
ATOM   35   N  N   . SER   A 1 46  ? 76.909  99.748  98.216  1.00 113.98 ? 46  SER   A N   1 
ATOM   36   C  CA  . SER   A 1 46  ? 76.945  98.335  97.877  1.00 113.98 ? 46  SER   A CA  1 
ATOM   37   C  C   . SER   A 1 46  ? 77.818  97.589  98.876  1.00 113.98 ? 46  SER   A C   1 
ATOM   38   O  O   . SER   A 1 46  ? 78.782  98.139  99.415  1.00 113.98 ? 46  SER   A O   1 
ATOM   39   C  CB  . SER   A 1 46  ? 77.474  98.111  96.453  1.00 113.98 ? 46  SER   A CB  1 
ATOM   40   O  OG  . SER   A 1 46  ? 77.473  96.734  96.121  1.00 113.98 ? 46  SER   A OG  1 
ATOM   41   N  N   . LYS   A 1 47  ? 77.464  96.325  99.119  1.00 115.88 ? 47  LYS   A N   1 
ATOM   42   C  CA  . LYS   A 1 47  ? 78.233  95.496  100.040 1.00 115.88 ? 47  LYS   A CA  1 
ATOM   43   C  C   . LYS   A 1 47  ? 79.601  95.131  99.480  1.00 115.88 ? 47  LYS   A C   1 
ATOM   44   O  O   . LYS   A 1 47  ? 80.496  94.759  100.247 1.00 115.88 ? 47  LYS   A O   1 
ATOM   45   C  CB  . LYS   A 1 47  ? 77.451  94.224  100.373 1.00 115.88 ? 47  LYS   A CB  1 
ATOM   46   C  CG  . LYS   A 1 47  ? 76.179  94.468  101.167 1.00 115.88 ? 47  LYS   A CG  1 
ATOM   47   C  CD  . LYS   A 1 47  ? 75.401  93.178  101.368 1.00 115.88 ? 47  LYS   A CD  1 
ATOM   48   C  CE  . LYS   A 1 47  ? 73.993  93.453  101.868 1.00 115.88 ? 47  LYS   A CE  1 
ATOM   49   N  NZ  . LYS   A 1 47  ? 73.170  92.214  101.916 1.00 115.88 ? 47  LYS   A NZ  1 
ATOM   50   N  N   . ILE   A 1 48  ? 79.780  95.229  98.163  1.00 110.87 ? 48  ILE   A N   1 
ATOM   51   C  CA  . ILE   A 1 48  ? 81.047  94.880  97.531  1.00 110.87 ? 48  ILE   A CA  1 
ATOM   52   C  C   . ILE   A 1 48  ? 81.977  96.088  97.417  1.00 110.87 ? 48  ILE   A C   1 
ATOM   53   O  O   . ILE   A 1 48  ? 83.199  95.914  97.275  1.00 110.87 ? 48  ILE   A O   1 
ATOM   54   C  CB  . ILE   A 1 48  ? 80.748  94.246  96.157  1.00 110.87 ? 48  ILE   A CB  1 
ATOM   55   C  CG1 . ILE   A 1 48  ? 79.956  92.951  96.339  1.00 110.87 ? 48  ILE   A CG1 1 
ATOM   56   C  CG2 . ILE   A 1 48  ? 82.011  93.923  95.393  1.00 110.87 ? 48  ILE   A CG2 1 
ATOM   57   C  CD1 . ILE   A 1 48  ? 79.395  92.393  95.050  1.00 110.87 ? 48  ILE   A CD1 1 
ATOM   58   N  N   . ASP   A 1 49  ? 81.433  97.305  97.504  1.00 109.86 ? 49  ASP   A N   1 
ATOM   59   C  CA  . ASP   A 1 49  ? 82.253  98.507  97.391  1.00 109.86 ? 49  ASP   A CA  1 
ATOM   60   C  C   . ASP   A 1 49  ? 83.271  98.593  98.521  1.00 109.86 ? 49  ASP   A C   1 
ATOM   61   O  O   . ASP   A 1 49  ? 84.428  98.961  98.294  1.00 109.86 ? 49  ASP   A O   1 
ATOM   62   C  CB  . ASP   A 1 49  ? 81.361  99.748  97.385  1.00 109.86 ? 49  ASP   A CB  1 
ATOM   63   C  CG  . ASP   A 1 49  ? 80.671  99.964  96.054  1.00 109.86 ? 49  ASP   A CG  1 
ATOM   64   O  OD1 . ASP   A 1 49  ? 81.181  99.464  95.031  1.00 109.86 ? 49  ASP   A OD1 1 
ATOM   65   O  OD2 . ASP   A 1 49  ? 79.618  100.634 96.033  1.00 109.86 ? 49  ASP   A OD2 1 
ATOM   66   N  N   . PHE   A 1 50  ? 82.855  98.266  99.747  1.00 100.85 ? 50  PHE   A N   1 
ATOM   67   C  CA  . PHE   A 1 50  ? 83.778  98.287  100.878 1.00 100.85 ? 50  PHE   A CA  1 
ATOM   68   C  C   . PHE   A 1 50  ? 84.912  97.290  100.679 1.00 100.85 ? 50  PHE   A C   1 
ATOM   69   O  O   . PHE   A 1 50  ? 86.081  97.596  100.946 1.00 100.85 ? 50  PHE   A O   1 
ATOM   70   C  CB  . PHE   A 1 50  ? 83.020  97.988  102.172 1.00 100.85 ? 50  PHE   A CB  1 
ATOM   71   C  CG  . PHE   A 1 50  ? 83.907  97.588  103.318 1.00 100.85 ? 50  PHE   A CG  1 
ATOM   72   C  CD1 . PHE   A 1 50  ? 84.584  98.544  104.055 1.00 100.85 ? 50  PHE   A CD1 1 
ATOM   73   C  CD2 . PHE   A 1 50  ? 84.060  96.254  103.659 1.00 100.85 ? 50  PHE   A CD2 1 
ATOM   74   C  CE1 . PHE   A 1 50  ? 85.396  98.177  105.111 1.00 100.85 ? 50  PHE   A CE1 1 
ATOM   75   C  CE2 . PHE   A 1 50  ? 84.873  95.881  104.711 1.00 100.85 ? 50  PHE   A CE2 1 
ATOM   76   C  CZ  . PHE   A 1 50  ? 85.541  96.844  105.437 1.00 100.85 ? 50  PHE   A CZ  1 
ATOM   77   N  N   . VAL   A 1 51  ? 84.580  96.084  100.214 1.00 98.94  ? 51  VAL   A N   1 
ATOM   78   C  CA  . VAL   A 1 51  ? 85.597  95.057  100.008 1.00 98.94  ? 51  VAL   A CA  1 
ATOM   79   C  C   . VAL   A 1 51  ? 86.595  95.506  98.949  1.00 98.94  ? 51  VAL   A C   1 
ATOM   80   O  O   . VAL   A 1 51  ? 87.811  95.364  99.120  1.00 98.94  ? 51  VAL   A O   1 
ATOM   81   C  CB  . VAL   A 1 51  ? 84.938  93.717  99.635  1.00 98.94  ? 51  VAL   A CB  1 
ATOM   82   C  CG1 . VAL   A 1 51  ? 85.994  92.699  99.234  1.00 98.94  ? 51  VAL   A CG1 1 
ATOM   83   C  CG2 . VAL   A 1 51  ? 84.109  93.199  100.798 1.00 98.94  ? 51  VAL   A CG2 1 
ATOM   84   N  N   . LEU   A 1 52  ? 86.097  96.061  97.842  1.00 98.40  ? 52  LEU   A N   1 
ATOM   85   C  CA  . LEU   A 1 52  ? 86.998  96.533  96.791  1.00 98.40  ? 52  LEU   A CA  1 
ATOM   86   C  C   . LEU   A 1 52  ? 87.862  97.693  97.274  1.00 98.40  ? 52  LEU   A C   1 
ATOM   87   O  O   . LEU   A 1 52  ? 89.054  97.766  96.955  1.00 98.40  ? 52  LEU   A O   1 
ATOM   88   C  CB  . LEU   A 1 52  ? 86.208  96.922  95.542  1.00 98.40  ? 52  LEU   A CB  1 
ATOM   89   C  CG  . LEU   A 1 52  ? 86.033  95.819  94.495  1.00 98.40  ? 52  LEU   A CG  1 
ATOM   90   C  CD1 . LEU   A 1 52  ? 87.378  95.481  93.881  1.00 98.40  ? 52  LEU   A CD1 1 
ATOM   91   C  CD2 . LEU   A 1 52  ? 85.422  94.574  95.095  1.00 98.40  ? 52  LEU   A CD2 1 
ATOM   92   N  N   . SER   A 1 53  ? 87.279  98.614  98.046  1.00 94.52  ? 53  SER   A N   1 
ATOM   93   C  CA  . SER   A 1 53  ? 88.048  99.745  98.556  1.00 94.52  ? 53  SER   A CA  1 
ATOM   94   C  C   . SER   A 1 53  ? 89.168  99.276  99.477  1.00 94.52  ? 53  SER   A C   1 
ATOM   95   O  O   . SER   A 1 53  ? 90.316  99.721  99.357  1.00 94.52  ? 53  SER   A O   1 
ATOM   96   C  CB  . SER   A 1 53  ? 87.123  100.720 99.283  1.00 94.52  ? 53  SER   A CB  1 
ATOM   97   O  OG  . SER   A 1 53  ? 87.855  101.794 99.846  1.00 94.52  ? 53  SER   A OG  1 
ATOM   98   N  N   . VAL   A 1 54  ? 88.855  98.360  100.397 1.00 93.39  ? 54  VAL   A N   1 
ATOM   99   C  CA  . VAL   A 1 54  ? 89.884  97.835  101.291 1.00 93.39  ? 54  VAL   A CA  1 
ATOM   100  C  C   . VAL   A 1 54  ? 90.947  97.087  100.498 1.00 93.39  ? 54  VAL   A C   1 
ATOM   101  O  O   . VAL   A 1 54  ? 92.149  97.270  100.724 1.00 93.39  ? 54  VAL   A O   1 
ATOM   102  C  CB  . VAL   A 1 54  ? 89.256  96.947  102.380 1.00 93.39  ? 54  VAL   A CB  1 
ATOM   103  C  CG1 . VAL   A 1 54  ? 90.337  96.343  103.256 1.00 93.39  ? 54  VAL   A CG1 1 
ATOM   104  C  CG2 . VAL   A 1 54  ? 88.298  97.759  103.227 1.00 93.39  ? 54  VAL   A CG2 1 
ATOM   105  N  N   . ALA   A 1 55  ? 90.527  96.252  99.543  1.00 87.12  ? 55  ALA   A N   1 
ATOM   106  C  CA  . ALA   A 1 55  ? 91.482  95.470  98.765  1.00 87.12  ? 55  ALA   A CA  1 
ATOM   107  C  C   . ALA   A 1 55  ? 92.434  96.374  97.994  1.00 87.12  ? 55  ALA   A C   1 
ATOM   108  O  O   . ALA   A 1 55  ? 93.645  96.129  97.956  1.00 87.12  ? 55  ALA   A O   1 
ATOM   109  C  CB  . ALA   A 1 55  ? 90.740  94.531  97.816  1.00 87.12  ? 55  ALA   A CB  1 
ATOM   110  N  N   . GLY   A 1 56  ? 91.890  97.394  97.337  1.00 84.38  ? 56  GLY   A N   1 
ATOM   111  C  CA  . GLY   A 1 56  ? 92.715  98.294  96.549  1.00 84.38  ? 56  GLY   A CA  1 
ATOM   112  C  C   . GLY   A 1 56  ? 93.648  99.076  97.440  1.00 84.38  ? 56  GLY   A C   1 
ATOM   113  O  O   . GLY   A 1 56  ? 94.729  99.482  97.017  1.00 84.38  ? 56  GLY   A O   1 
ATOM   114  N  N   . GLY   A 1 57  ? 93.242  99.277  98.687  1.00 83.71  ? 57  GLY   A N   1 
ATOM   115  C  CA  . GLY   A 1 57  ? 94.062  100.022 99.620  1.00 83.71  ? 57  GLY   A CA  1 
ATOM   116  C  C   . GLY   A 1 57  ? 95.393  99.358  99.898  1.00 83.71  ? 57  GLY   A C   1 
ATOM   117  O  O   . GLY   A 1 57  ? 96.413  100.039 99.995  1.00 83.71  ? 57  GLY   A O   1 
ATOM   118  N  N   . PHE   A 1 58  ? 95.401  98.035  100.027 1.00 82.78  ? 58  PHE   A N   1 
ATOM   119  C  CA  . PHE   A 1 58  ? 96.643  97.355  100.387 1.00 82.78  ? 58  PHE   A CA  1 
ATOM   120  C  C   . PHE   A 1 58  ? 97.436  96.674  99.257  1.00 82.78  ? 58  PHE   A C   1 
ATOM   121  O  O   . PHE   A 1 58  ? 98.522  96.155  99.521  1.00 82.78  ? 58  PHE   A O   1 
ATOM   122  C  CB  . PHE   A 1 58  ? 96.440  96.391  101.573 1.00 82.78  ? 58  PHE   A CB  1 
ATOM   123  C  CG  . PHE   A 1 58  ? 95.363  95.358  101.366 1.00 82.78  ? 58  PHE   A CG  1 
ATOM   124  C  CD1 . PHE   A 1 58  ? 94.283  95.293  102.227 1.00 82.78  ? 58  PHE   A CD1 1 
ATOM   125  C  CD2 . PHE   A 1 58  ? 95.442  94.434  100.339 1.00 82.78  ? 58  PHE   A CD2 1 
ATOM   126  C  CE1 . PHE   A 1 58  ? 93.298  94.342  102.057 1.00 82.78  ? 58  PHE   A CE1 1 
ATOM   127  C  CE2 . PHE   A 1 58  ? 94.461  93.482  100.160 1.00 82.78  ? 58  PHE   A CE2 1 
ATOM   128  C  CZ  . PHE   A 1 58  ? 93.388  93.436  101.022 1.00 82.78  ? 58  PHE   A CZ  1 
ATOM   129  N  N   . VAL   A 1 59  ? 96.911  96.490  98.068  1.00 78.94  ? 59  VAL   A N   1 
ATOM   130  C  CA  . VAL   A 1 59  ? 97.750  95.938  96.982  1.00 78.94  ? 59  VAL   A CA  1 
ATOM   131  C  C   . VAL   A 1 59  ? 98.277  97.105  96.141  1.00 78.94  ? 59  VAL   A C   1 
ATOM   132  O  O   . VAL   A 1 59  ? 97.513  98.007  95.867  1.00 78.94  ? 59  VAL   A O   1 
ATOM   133  C  CB  . VAL   A 1 59  ? 97.071  94.822  96.172  1.00 78.94  ? 59  VAL   A CB  1 
ATOM   134  C  CG1 . VAL   A 1 59  ? 97.071  93.515  96.933  1.00 78.94  ? 59  VAL   A CG1 1 
ATOM   135  C  CG2 . VAL   A 1 59  ? 95.673  95.202  95.727  1.00 78.94  ? 59  VAL   A CG2 1 
ATOM   136  N  N   . GLY   A 1 60  ? 99.560  97.114  95.802  1.00 70.63  ? 60  GLY   A N   1 
ATOM   137  C  CA  . GLY   A 1 60  ? 100.115 98.240  95.072  1.00 70.63  ? 60  GLY   A CA  1 
ATOM   138  C  C   . GLY   A 1 60  ? 101.624 98.255  95.060  1.00 70.63  ? 60  GLY   A C   1 
ATOM   139  O  O   . GLY   A 1 60  ? 102.244 97.203  95.061  1.00 70.63  ? 60  GLY   A O   1 
ATOM   140  N  N   . LEU   A 1 61  ? 102.222 99.439  95.073  1.00 64.55  ? 61  LEU   A N   1 
ATOM   141  C  CA  . LEU   A 1 61  ? 103.678 99.537  94.981  1.00 64.55  ? 61  LEU   A CA  1 
ATOM   142  C  C   . LEU   A 1 61  ? 104.434 99.195  96.268  1.00 64.55  ? 61  LEU   A C   1 
ATOM   143  O  O   . LEU   A 1 61  ? 105.656 99.324  96.313  1.00 64.55  ? 61  LEU   A O   1 
ATOM   144  C  CB  . LEU   A 1 61  ? 104.083 100.924 94.474  1.00 64.55  ? 61  LEU   A CB  1 
ATOM   145  C  CG  . LEU   A 1 61  ? 103.488 101.299 93.115  1.00 64.55  ? 61  LEU   A CG  1 
ATOM   146  C  CD1 . LEU   A 1 61  ? 103.831 102.730 92.738  1.00 64.55  ? 61  LEU   A CD1 1 
ATOM   147  C  CD2 . LEU   A 1 61  ? 103.950 100.331 92.037  1.00 64.55  ? 61  LEU   A CD2 1 
ATOM   148  N  N   . GLY   A 1 62  ? 103.729 98.758  97.309  1.00 65.54  ? 62  GLY   A N   1 
ATOM   149  C  CA  . GLY   A 1 62  ? 104.412 98.354  98.528  1.00 65.54  ? 62  GLY   A CA  1 
ATOM   150  C  C   . GLY   A 1 62  ? 104.885 96.913  98.504  1.00 65.54  ? 62  GLY   A C   1 
ATOM   151  O  O   . GLY   A 1 62  ? 105.973 96.599  98.994  1.00 65.54  ? 62  GLY   A O   1 
ATOM   152  N  N   . ASN   A 1 63  ? 104.079 96.017  97.940  1.00 68.88  ? 63  ASN   A N   1 
ATOM   153  C  CA  . ASN   A 1 63  ? 104.373 94.591  97.955  1.00 68.88  ? 63  ASN   A CA  1 
ATOM   154  C  C   . ASN   A 1 63  ? 104.953 94.079  96.641  1.00 68.88  ? 63  ASN   A C   1 
ATOM   155  O  O   . ASN   A 1 63  ? 105.138 92.867  96.491  1.00 68.88  ? 63  ASN   A O   1 
ATOM   156  C  CB  . ASN   A 1 63  ? 103.114 93.804  98.327  1.00 68.88  ? 63  ASN   A CB  1 
ATOM   157  C  CG  . ASN   A 1 63  ? 101.955 94.071  97.390  1.00 68.88  ? 63  ASN   A CG  1 
ATOM   158  O  OD1 . ASN   A 1 63  ? 102.104 94.742  96.370  1.00 68.88  ? 63  ASN   A OD1 1 
ATOM   159  N  ND2 . ASN   A 1 63  ? 100.784 93.553  97.740  1.00 68.88  ? 63  ASN   A ND2 1 
ATOM   160  N  N   . VAL   A 1 64  ? 105.247 94.966  95.689  1.00 70.30  ? 64  VAL   A N   1 
ATOM   161  C  CA  . VAL   A 1 64  ? 105.858 94.585  94.424  1.00 70.30  ? 64  VAL   A CA  1 
ATOM   162  C  C   . VAL   A 1 64  ? 107.188 95.294  94.204  1.00 70.30  ? 64  VAL   A C   1 
ATOM   163  O  O   . VAL   A 1 64  ? 108.067 94.776  93.505  1.00 70.30  ? 64  VAL   A O   1 
ATOM   164  C  CB  . VAL   A 1 64  ? 104.896 94.846  93.241  1.00 70.30  ? 64  VAL   A CB  1 
ATOM   165  C  CG1 . VAL   A 1 64  ? 104.519 96.313  93.168  1.00 70.30  ? 64  VAL   A CG1 1 
ATOM   166  C  CG2 . VAL   A 1 64  ? 105.488 94.361  91.925  1.00 70.30  ? 64  VAL   A CG2 1 
ATOM   167  N  N   . TRP   A 1 65  ? 107.372 96.464  94.812  1.00 69.71  ? 65  TRP   A N   1 
ATOM   168  C  CA  . TRP   A 1 65  ? 108.590 97.255  94.688  1.00 69.71  ? 65  TRP   A CA  1 
ATOM   169  C  C   . TRP   A 1 65  ? 109.411 97.313  95.964  1.00 69.71  ? 65  TRP   A C   1 
ATOM   170  O  O   . TRP   A 1 65  ? 110.601 96.996  95.940  1.00 69.71  ? 65  TRP   A O   1 
ATOM   171  C  CB  . TRP   A 1 65  ? 108.244 98.683  94.257  1.00 69.71  ? 65  TRP   A CB  1 
ATOM   172  C  CG  . TRP   A 1 65  ? 109.367 99.650  94.447  1.00 69.71  ? 65  TRP   A CG  1 
ATOM   173  C  CD1 . TRP   A 1 65  ? 110.582 99.631  93.829  1.00 69.71  ? 65  TRP   A CD1 1 
ATOM   174  C  CD2 . TRP   A 1 65  ? 109.384 100.774 95.334  1.00 69.71  ? 65  TRP   A CD2 1 
ATOM   175  N  NE1 . TRP   A 1 65  ? 111.351 100.681 94.268  1.00 69.71  ? 65  TRP   A NE1 1 
ATOM   176  C  CE2 . TRP   A 1 65  ? 110.638 101.397 95.194  1.00 69.71  ? 65  TRP   A CE2 1 
ATOM   177  C  CE3 . TRP   A 1 65  ? 108.458 101.316 96.230  1.00 69.71  ? 65  TRP   A CE3 1 
ATOM   178  C  CZ2 . TRP   A 1 65  ? 110.990 102.533 95.917  1.00 69.71  ? 65  TRP   A CZ2 1 
ATOM   179  C  CZ3 . TRP   A 1 65  ? 108.810 102.444 96.946  1.00 69.71  ? 65  TRP   A CZ3 1 
ATOM   180  C  CH2 . TRP   A 1 65  ? 110.065 103.040 96.786  1.00 69.71  ? 65  TRP   A CH2 1 
ATOM   181  N  N   . ARG   A 1 66  ? 108.805 97.716  97.083  1.00 67.51  ? 66  ARG   A N   1 
ATOM   182  C  CA  . ARG   A 1 66  ? 109.562 97.871  98.320  1.00 67.51  ? 66  ARG   A CA  1 
ATOM   183  C  C   . ARG   A 1 66  ? 109.908 96.520  98.932  1.00 67.51  ? 66  ARG   A C   1 
ATOM   184  O  O   . ARG   A 1 66  ? 111.003 96.340  99.478  1.00 67.51  ? 66  ARG   A O   1 
ATOM   185  C  CB  . ARG   A 1 66  ? 108.778 98.730  99.312  1.00 67.51  ? 66  ARG   A CB  1 
ATOM   186  C  CG  . ARG   A 1 66  ? 109.652 99.429  100.338 1.00 67.51  ? 66  ARG   A CG  1 
ATOM   187  C  CD  . ARG   A 1 66  ? 108.861 100.445 101.144 1.00 67.51  ? 66  ARG   A CD  1 
ATOM   188  N  NE  . ARG   A 1 66  ? 109.537 100.800 102.386 1.00 67.51  ? 66  ARG   A NE  1 
ATOM   189  C  CZ  . ARG   A 1 66  ? 109.376 100.160 103.536 1.00 67.51  ? 66  ARG   A CZ  1 
ATOM   190  N  NH1 . ARG   A 1 66  ? 108.559 99.125  103.642 1.00 67.51  ? 66  ARG   A NH1 1 
ATOM   191  N  NH2 . ARG   A 1 66  ? 110.049 100.569 104.607 1.00 67.51  ? 66  ARG   A NH2 1 
ATOM   192  N  N   . PHE   A 1 67  ? 108.983 95.562  98.866  1.00 69.75  ? 67  PHE   A N   1 
ATOM   193  C  CA  . PHE   A 1 67  ? 109.210 94.248  99.458  1.00 69.75  ? 67  PHE   A CA  1 
ATOM   194  C  C   . PHE   A 1 67  ? 110.449 93.579  98.869  1.00 69.75  ? 67  PHE   A C   1 
ATOM   195  O  O   . PHE   A 1 67  ? 111.311 93.124  99.634  1.00 69.75  ? 67  PHE   A O   1 
ATOM   196  C  CB  . PHE   A 1 67  ? 107.981 93.350  99.285  1.00 69.75  ? 67  PHE   A CB  1 
ATOM   197  C  CG  . PHE   A 1 67  ? 108.190 91.938  99.758  1.00 69.75  ? 67  PHE   A CG  1 
ATOM   198  C  CD1 . PHE   A 1 67  ? 108.299 91.657  101.109 1.00 69.75  ? 67  PHE   A CD1 1 
ATOM   199  C  CD2 . PHE   A 1 67  ? 108.281 90.895  98.853  1.00 69.75  ? 67  PHE   A CD2 1 
ATOM   200  C  CE1 . PHE   A 1 67  ? 108.491 90.363  101.547 1.00 69.75  ? 67  PHE   A CE1 1 
ATOM   201  C  CE2 . PHE   A 1 67  ? 108.473 89.598  99.287  1.00 69.75  ? 67  PHE   A CE2 1 
ATOM   202  C  CZ  . PHE   A 1 67  ? 108.578 89.333  100.636 1.00 69.75  ? 67  PHE   A CZ  1 
ATOM   203  N  N   . PRO   A 1 68  ? 110.595 93.489  97.540  1.00 70.15  ? 68  PRO   A N   1 
ATOM   204  C  CA  . PRO   A 1 68  ? 111.867 92.965  97.013  1.00 70.15  ? 68  PRO   A CA  1 
ATOM   205  C  C   . PRO   A 1 68  ? 113.053 93.832  97.389  1.00 70.15  ? 68  PRO   A C   1 
ATOM   206  O  O   . PRO   A 1 68  ? 114.143 93.309  97.635  1.00 70.15  ? 68  PRO   A O   1 
ATOM   207  C  CB  . PRO   A 1 68  ? 111.637 92.915  95.497  1.00 70.15  ? 68  PRO   A CB  1 
ATOM   208  C  CG  . PRO   A 1 68  ? 110.193 93.138  95.284  1.00 70.15  ? 68  PRO   A CG  1 
ATOM   209  C  CD  . PRO   A 1 68  ? 109.686 93.892  96.452  1.00 70.15  ? 68  PRO   A CD  1 
ATOM   210  N  N   . TYR   A 1 69  ? 112.864 95.151  97.462  1.00 73.36  ? 69  TYR   A N   1 
ATOM   211  C  CA  . TYR   A 1 69  ? 113.956 96.031  97.867  1.00 73.36  ? 69  TYR   A CA  1 
ATOM   212  C  C   . TYR   A 1 69  ? 114.416 95.726  99.288  1.00 73.36  ? 69  TYR   A C   1 
ATOM   213  O  O   . TYR   A 1 69  ? 115.619 95.595  99.544  1.00 73.36  ? 69  TYR   A O   1 
ATOM   214  C  CB  . TYR   A 1 69  ? 113.516 97.490  97.736  1.00 73.36  ? 69  TYR   A CB  1 
ATOM   215  C  CG  . TYR   A 1 69  ? 114.307 98.472  98.571  1.00 73.36  ? 69  TYR   A CG  1 
ATOM   216  C  CD1 . TYR   A 1 69  ? 115.687 98.568  98.455  1.00 73.36  ? 69  TYR   A CD1 1 
ATOM   217  C  CD2 . TYR   A 1 69  ? 113.667 99.314  99.470  1.00 73.36  ? 69  TYR   A CD2 1 
ATOM   218  C  CE1 . TYR   A 1 69  ? 116.404 99.462  99.219  1.00 73.36  ? 69  TYR   A CE1 1 
ATOM   219  C  CE2 . TYR   A 1 69  ? 114.376 100.213 100.235 1.00 73.36  ? 69  TYR   A CE2 1 
ATOM   220  C  CZ  . TYR   A 1 69  ? 115.744 100.284 100.105 1.00 73.36  ? 69  TYR   A CZ  1 
ATOM   221  O  OH  . TYR   A 1 69  ? 116.457 101.180 100.865 1.00 73.36  ? 69  TYR   A OH  1 
ATOM   222  N  N   . LEU   A 1 70  ? 113.473 95.595  100.222 1.00 72.06  ? 70  LEU   A N   1 
ATOM   223  C  CA  . LEU   A 1 70  ? 113.840 95.325  101.608 1.00 72.06  ? 70  LEU   A CA  1 
ATOM   224  C  C   . LEU   A 1 70  ? 114.425 93.926  101.760 1.00 72.06  ? 70  LEU   A C   1 
ATOM   225  O  O   . LEU   A 1 70  ? 115.390 93.724  102.505 1.00 72.06  ? 70  LEU   A O   1 
ATOM   226  C  CB  . LEU   A 1 70  ? 112.628 95.518  102.518 1.00 72.06  ? 70  LEU   A CB  1 
ATOM   227  C  CG  . LEU   A 1 70  ? 112.249 96.984  102.736 1.00 72.06  ? 70  LEU   A CG  1 
ATOM   228  C  CD1 . LEU   A 1 70  ? 111.217 97.125  103.838 1.00 72.06  ? 70  LEU   A CD1 1 
ATOM   229  C  CD2 . LEU   A 1 70  ? 113.484 97.814  103.048 1.00 72.06  ? 70  LEU   A CD2 1 
ATOM   230  N  N   . CYS   A 1 71  ? 113.852 92.943  101.062 1.00 76.24  ? 71  CYS   A N   1 
ATOM   231  C  CA  . CYS   A 1 71  ? 114.404 91.594  101.101 1.00 76.24  ? 71  CYS   A CA  1 
ATOM   232  C  C   . CYS   A 1 71  ? 115.760 91.498  100.413 1.00 76.24  ? 71  CYS   A C   1 
ATOM   233  O  O   . CYS   A 1 71  ? 116.514 90.560  100.694 1.00 76.24  ? 71  CYS   A O   1 
ATOM   234  C  CB  . CYS   A 1 71  ? 113.426 90.607  100.461 1.00 76.24  ? 71  CYS   A CB  1 
ATOM   235  S  SG  . CYS   A 1 71  ? 113.888 88.869  100.636 1.00 76.24  ? 71  CYS   A SG  1 
ATOM   236  N  N   . TYR   A 1 72  ? 116.082 92.437  99.527  1.00 79.78  ? 72  TYR   A N   1 
ATOM   237  C  CA  . TYR   A 1 72  ? 117.367 92.469  98.845  1.00 79.78  ? 72  TYR   A CA  1 
ATOM   238  C  C   . TYR   A 1 72  ? 118.422 93.237  99.625  1.00 79.78  ? 72  TYR   A C   1 
ATOM   239  O  O   . TYR   A 1 72  ? 119.618 92.977  99.455  1.00 79.78  ? 72  TYR   A O   1 
ATOM   240  C  CB  . TYR   A 1 72  ? 117.194 93.096  97.459  1.00 79.78  ? 72  TYR   A CB  1 
ATOM   241  C  CG  . TYR   A 1 72  ? 118.433 93.072  96.601  1.00 79.78  ? 72  TYR   A CG  1 
ATOM   242  C  CD1 . TYR   A 1 72  ? 119.024 91.872  96.236  1.00 79.78  ? 72  TYR   A CD1 1 
ATOM   243  C  CD2 . TYR   A 1 72  ? 119.008 94.251  96.150  1.00 79.78  ? 72  TYR   A CD2 1 
ATOM   244  C  CE1 . TYR   A 1 72  ? 120.152 91.847  95.448  1.00 79.78  ? 72  TYR   A CE1 1 
ATOM   245  C  CE2 . TYR   A 1 72  ? 120.138 94.235  95.364  1.00 79.78  ? 72  TYR   A CE2 1 
ATOM   246  C  CZ  . TYR   A 1 72  ? 120.706 93.031  95.016  1.00 79.78  ? 72  TYR   A CZ  1 
ATOM   247  O  OH  . TYR   A 1 72  ? 121.832 93.013  94.229  1.00 79.78  ? 72  TYR   A OH  1 
ATOM   248  N  N   . LYS   A 1 73  ? 118.002 94.182  100.469 1.00 77.65  ? 73  LYS   A N   1 
ATOM   249  C  CA  . LYS   A 1 73  ? 118.961 94.937  101.269 1.00 77.65  ? 73  LYS   A CA  1 
ATOM   250  C  C   . LYS   A 1 73  ? 119.728 94.022  102.215 1.00 77.65  ? 73  LYS   A C   1 
ATOM   251  O  O   . LYS   A 1 73  ? 120.934 94.199  102.422 1.00 77.65  ? 73  LYS   A O   1 
ATOM   252  C  CB  . LYS   A 1 73  ? 118.241 96.038  102.048 1.00 77.65  ? 73  LYS   A CB  1 
ATOM   253  C  CG  . LYS   A 1 73  ? 119.162 97.113  102.595 1.00 77.65  ? 73  LYS   A CG  1 
ATOM   254  C  CD  . LYS   A 1 73  ? 118.380 98.171  103.354 1.00 77.65  ? 73  LYS   A CD  1 
ATOM   255  C  CE  . LYS   A 1 73  ? 119.282 98.956  104.291 1.00 77.65  ? 73  LYS   A CE  1 
ATOM   256  N  NZ  . LYS   A 1 73  ? 119.914 98.080  105.316 1.00 77.65  ? 73  LYS   A NZ  1 
ATOM   257  N  N   . ASN   A 1 74  ? 119.045 93.040  102.798 1.00 76.85  ? 74  ASN   A N   1 
ATOM   258  C  CA  . ASN   A 1 74  ? 119.664 92.052  103.674 1.00 76.85  ? 74  ASN   A CA  1 
ATOM   259  C  C   . ASN   A 1 74  ? 119.792 90.744  102.902 1.00 76.85  ? 74  ASN   A C   1 
ATOM   260  O  O   . ASN   A 1 74  ? 118.803 90.231  102.369 1.00 76.85  ? 74  ASN   A O   1 
ATOM   261  C  CB  . ASN   A 1 74  ? 118.841 91.865  104.945 1.00 76.85  ? 74  ASN   A CB  1 
ATOM   262  C  CG  . ASN   A 1 74  ? 118.528 93.177  105.630 1.00 76.85  ? 74  ASN   A CG  1 
ATOM   263  O  OD1 . ASN   A 1 74  ? 119.401 93.800  106.233 1.00 76.85  ? 74  ASN   A OD1 1 
ATOM   264  N  ND2 . ASN   A 1 74  ? 117.278 93.610  105.534 1.00 76.85  ? 74  ASN   A ND2 1 
ATOM   265  N  N   . GLY   A 1 75  ? 121.004 90.207  102.847 1.00 81.17  ? 75  GLY   A N   1 
ATOM   266  C  CA  . GLY   A 1 75  ? 121.259 89.014  102.063 1.00 81.17  ? 75  GLY   A CA  1 
ATOM   267  C  C   . GLY   A 1 75  ? 120.559 87.790  102.623 1.00 81.17  ? 75  GLY   A C   1 
ATOM   268  O  O   . GLY   A 1 75  ? 120.184 87.711  103.792 1.00 81.17  ? 75  GLY   A O   1 
ATOM   269  N  N   . GLY   A 1 76  ? 120.378 86.808  101.743 1.00 82.63  ? 76  GLY   A N   1 
ATOM   270  C  CA  . GLY   A 1 76  ? 119.748 85.564  102.131 1.00 82.63  ? 76  GLY   A CA  1 
ATOM   271  C  C   . GLY   A 1 76  ? 118.252 85.716  102.365 1.00 82.63  ? 76  GLY   A C   1 
ATOM   272  O  O   . GLY   A 1 76  ? 117.622 86.711  101.994 1.00 82.63  ? 76  GLY   A O   1 
ATOM   273  N  N   . GLY   A 1 77  ? 117.685 84.694  102.999 1.00 84.82  ? 77  GLY   A N   1 
ATOM   274  C  CA  . GLY   A 1 77  ? 116.266 84.674  103.296 1.00 84.82  ? 77  GLY   A CA  1 
ATOM   275  C  C   . GLY   A 1 77  ? 115.954 84.970  104.747 1.00 84.82  ? 77  GLY   A C   1 
ATOM   276  O  O   . GLY   A 1 77  ? 114.887 84.601  105.246 1.00 84.82  ? 77  GLY   A O   1 
ATOM   277  N  N   . ALA   A 1 78  ? 116.883 85.638  105.437 1.00 82.14  ? 78  ALA   A N   1 
ATOM   278  C  CA  . ALA   A 1 78  ? 116.665 85.999  106.833 1.00 82.14  ? 78  ALA   A CA  1 
ATOM   279  C  C   . ALA   A 1 78  ? 115.500 86.963  106.999 1.00 82.14  ? 78  ALA   A C   1 
ATOM   280  O  O   . ALA   A 1 78  ? 115.020 87.152  108.121 1.00 82.14  ? 78  ALA   A O   1 
ATOM   281  C  CB  . ALA   A 1 78  ? 117.934 86.609  107.425 1.00 82.14  ? 78  ALA   A CB  1 
ATOM   282  N  N   . PHE   A 1 79  ? 115.051 87.586  105.908 1.00 79.51  ? 79  PHE   A N   1 
ATOM   283  C  CA  . PHE   A 1 79  ? 113.868 88.439  105.953 1.00 79.51  ? 79  PHE   A CA  1 
ATOM   284  C  C   . PHE   A 1 79  ? 112.623 87.638  106.321 1.00 79.51  ? 79  PHE   A C   1 
ATOM   285  O  O   . PHE   A 1 79  ? 111.716 88.156  106.981 1.00 79.51  ? 79  PHE   A O   1 
ATOM   286  C  CB  . PHE   A 1 79  ? 113.694 89.126  104.595 1.00 79.51  ? 79  PHE   A CB  1 
ATOM   287  C  CG  . PHE   A 1 79  ? 112.641 90.201  104.573 1.00 79.51  ? 79  PHE   A CG  1 
ATOM   288  C  CD1 . PHE   A 1 79  ? 111.298 89.883  104.456 1.00 79.51  ? 79  PHE   A CD1 1 
ATOM   289  C  CD2 . PHE   A 1 79  ? 113.001 91.534  104.643 1.00 79.51  ? 79  PHE   A CD2 1 
ATOM   290  C  CE1 . PHE   A 1 79  ? 110.338 90.873  104.431 1.00 79.51  ? 79  PHE   A CE1 1 
ATOM   291  C  CE2 . PHE   A 1 79  ? 112.044 92.528  104.616 1.00 79.51  ? 79  PHE   A CE2 1 
ATOM   292  C  CZ  . PHE   A 1 79  ? 110.712 92.196  104.510 1.00 79.51  ? 79  PHE   A CZ  1 
ATOM   293  N  N   . LEU   A 1 80  ? 112.569 86.369  105.909 1.00 79.29  ? 80  LEU   A N   1 
ATOM   294  C  CA  . LEU   A 1 80  ? 111.344 85.586  106.022 1.00 79.29  ? 80  LEU   A CA  1 
ATOM   295  C  C   . LEU   A 1 80  ? 111.048 85.126  107.445 1.00 79.29  ? 80  LEU   A C   1 
ATOM   296  O  O   . LEU   A 1 80  ? 109.872 85.000  107.804 1.00 79.29  ? 80  LEU   A O   1 
ATOM   297  C  CB  . LEU   A 1 80  ? 111.416 84.370  105.099 1.00 79.29  ? 80  LEU   A CB  1 
ATOM   298  C  CG  . LEU   A 1 80  ? 111.821 84.626  103.646 1.00 79.29  ? 80  LEU   A CG  1 
ATOM   299  C  CD1 . LEU   A 1 80  ? 111.724 83.340  102.844 1.00 79.29  ? 80  LEU   A CD1 1 
ATOM   300  C  CD2 . LEU   A 1 80  ? 110.962 85.716  103.024 1.00 79.29  ? 80  LEU   A CD2 1 
ATOM   301  N  N   . ILE   A 1 81  ? 112.068 84.850  108.252 1.00 72.94  ? 81  ILE   A N   1 
ATOM   302  C  CA  . ILE   A 1 81  ? 111.862 84.298  109.590 1.00 72.94  ? 81  ILE   A CA  1 
ATOM   303  C  C   . ILE   A 1 81  ? 111.036 85.253  110.450 1.00 72.94  ? 81  ILE   A C   1 
ATOM   304  O  O   . ILE   A 1 81  ? 110.054 84.812  111.065 1.00 72.94  ? 81  ILE   A O   1 
ATOM   305  C  CB  . ILE   A 1 81  ? 113.200 83.948  110.264 1.00 72.94  ? 81  ILE   A CB  1 
ATOM   306  C  CG1 . ILE   A 1 81  ? 114.030 83.038  109.357 1.00 72.94  ? 81  ILE   A CG1 1 
ATOM   307  C  CG2 . ILE   A 1 81  ? 112.962 83.293  111.614 1.00 72.94  ? 81  ILE   A CG2 1 
ATOM   308  C  CD1 . ILE   A 1 81  ? 113.298 81.795  108.901 1.00 72.94  ? 81  ILE   A CD1 1 
ATOM   309  N  N   . PRO   A 1 82  ? 111.362 86.551  110.533 1.00 72.37  ? 82  PRO   A N   1 
ATOM   310  C  CA  . PRO   A 1 82  ? 110.465 87.464  111.258 1.00 72.37  ? 82  PRO   A CA  1 
ATOM   311  C  C   . PRO   A 1 82  ? 109.189 87.775  110.502 1.00 72.37  ? 82  PRO   A C   1 
ATOM   312  O  O   . PRO   A 1 82  ? 108.213 88.202  111.128 1.00 72.37  ? 82  PRO   A O   1 
ATOM   313  C  CB  . PRO   A 1 82  ? 111.317 88.728  111.453 1.00 72.37  ? 82  PRO   A CB  1 
ATOM   314  C  CG  . PRO   A 1 82  ? 112.717 88.334  111.083 1.00 72.37  ? 82  PRO   A CG  1 
ATOM   315  C  CD  . PRO   A 1 82  ? 112.562 87.264  110.066 1.00 72.37  ? 82  PRO   A CD  1 
ATOM   316  N  N   . TYR   A 1 83  ? 109.166 87.565  109.183 1.00 71.68  ? 83  TYR   A N   1 
ATOM   317  C  CA  . TYR   A 1 83  ? 108.010 87.930  108.371 1.00 71.68  ? 83  TYR   A CA  1 
ATOM   318  C  C   . TYR   A 1 83  ? 106.755 87.203  108.843 1.00 71.68  ? 83  TYR   A C   1 
ATOM   319  O  O   . TYR   A 1 83  ? 105.746 87.829  109.184 1.00 71.68  ? 83  TYR   A O   1 
ATOM   320  C  CB  . TYR   A 1 83  ? 108.312 87.610  106.901 1.00 71.68  ? 83  TYR   A CB  1 
ATOM   321  C  CG  . TYR   A 1 83  ? 107.257 88.035  105.901 1.00 71.68  ? 83  TYR   A CG  1 
ATOM   322  C  CD1 . TYR   A 1 83  ? 106.101 87.291  105.717 1.00 71.68  ? 83  TYR   A CD1 1 
ATOM   323  C  CD2 . TYR   A 1 83  ? 107.442 89.158  105.107 1.00 71.68  ? 83  TYR   A CD2 1 
ATOM   324  C  CE1 . TYR   A 1 83  ? 105.145 87.670  104.800 1.00 71.68  ? 83  TYR   A CE1 1 
ATOM   325  C  CE2 . TYR   A 1 83  ? 106.491 89.545  104.184 1.00 71.68  ? 83  TYR   A CE2 1 
ATOM   326  C  CZ  . TYR   A 1 83  ? 105.345 88.797  104.036 1.00 71.68  ? 83  TYR   A CZ  1 
ATOM   327  O  OH  . TYR   A 1 83  ? 104.395 89.176  103.118 1.00 71.68  ? 83  TYR   A OH  1 
ATOM   328  N  N   . PHE   A 1 84  ? 106.823 85.871  108.915 1.00 72.78  ? 84  PHE   A N   1 
ATOM   329  C  CA  . PHE   A 1 84  ? 105.647 85.081  109.268 1.00 72.78  ? 84  PHE   A CA  1 
ATOM   330  C  C   . PHE   A 1 84  ? 105.267 85.278  110.730 1.00 72.78  ? 84  PHE   A C   1 
ATOM   331  O  O   . PHE   A 1 84  ? 104.077 85.336  111.073 1.00 72.78  ? 84  PHE   A O   1 
ATOM   332  C  CB  . PHE   A 1 84  ? 105.916 83.603  108.980 1.00 72.78  ? 84  PHE   A CB  1 
ATOM   333  C  CG  . PHE   A 1 84  ? 106.116 83.296  107.522 1.00 72.78  ? 84  PHE   A CG  1 
ATOM   334  C  CD1 . PHE   A 1 84  ? 105.583 84.120  106.545 1.00 72.78  ? 84  PHE   A CD1 1 
ATOM   335  C  CD2 . PHE   A 1 84  ? 106.860 82.196  107.130 1.00 72.78  ? 84  PHE   A CD2 1 
ATOM   336  C  CE1 . PHE   A 1 84  ? 105.775 83.846  105.205 1.00 72.78  ? 84  PHE   A CE1 1 
ATOM   337  C  CE2 . PHE   A 1 84  ? 107.056 81.916  105.791 1.00 72.78  ? 84  PHE   A CE2 1 
ATOM   338  C  CZ  . PHE   A 1 84  ? 106.512 82.743  104.827 1.00 72.78  ? 84  PHE   A CZ  1 
ATOM   339  N  N   . ILE   A 1 85  ? 106.269 85.366  111.608 1.00 69.57  ? 85  ILE   A N   1 
ATOM   340  C  CA  . ILE   A 1 85  ? 106.003 85.537  113.033 1.00 69.57  ? 85  ILE   A CA  1 
ATOM   341  C  C   . ILE   A 1 85  ? 105.289 86.857  113.280 1.00 69.57  ? 85  ILE   A C   1 
ATOM   342  O  O   . ILE   A 1 85  ? 104.260 86.907  113.964 1.00 69.57  ? 85  ILE   A O   1 
ATOM   343  C  CB  . ILE   A 1 85  ? 107.310 85.447  113.838 1.00 69.57  ? 85  ILE   A CB  1 
ATOM   344  C  CG1 . ILE   A 1 85  ? 107.935 84.060  113.685 1.00 69.57  ? 85  ILE   A CG1 1 
ATOM   345  C  CG2 . ILE   A 1 85  ? 107.052 85.759  115.301 1.00 69.57  ? 85  ILE   A CG2 1 
ATOM   346  C  CD1 . ILE   A 1 85  ? 109.343 83.963  114.227 1.00 69.57  ? 85  ILE   A CD1 1 
ATOM   347  N  N   . PHE   A 1 86  ? 105.814 87.945  112.710 1.00 69.09  ? 86  PHE   A N   1 
ATOM   348  C  CA  . PHE   A 1 86  ? 105.169 89.241  112.864 1.00 69.09  ? 86  PHE   A CA  1 
ATOM   349  C  C   . PHE   A 1 86  ? 103.802 89.258  112.199 1.00 69.09  ? 86  PHE   A C   1 
ATOM   350  O  O   . PHE   A 1 86  ? 102.866 89.870  112.724 1.00 69.09  ? 86  PHE   A O   1 
ATOM   351  C  CB  . PHE   A 1 86  ? 106.063 90.345  112.305 1.00 69.09  ? 86  PHE   A CB  1 
ATOM   352  C  CG  . PHE   A 1 86  ? 106.968 90.960  113.331 1.00 69.09  ? 86  PHE   A CG  1 
ATOM   353  C  CD1 . PHE   A 1 86  ? 106.481 91.899  114.226 1.00 69.09  ? 86  PHE   A CD1 1 
ATOM   354  C  CD2 . PHE   A 1 86  ? 108.302 90.601  113.403 1.00 69.09  ? 86  PHE   A CD2 1 
ATOM   355  C  CE1 . PHE   A 1 86  ? 107.307 92.468  115.174 1.00 69.09  ? 86  PHE   A CE1 1 
ATOM   356  C  CE2 . PHE   A 1 86  ? 109.134 91.168  114.350 1.00 69.09  ? 86  PHE   A CE2 1 
ATOM   357  C  CZ  . PHE   A 1 86  ? 108.635 92.103  115.237 1.00 69.09  ? 86  PHE   A CZ  1 
ATOM   358  N  N   . LEU   A 1 87  ? 103.657 88.576  111.056 1.00 69.22  ? 87  LEU   A N   1 
ATOM   359  C  CA  . LEU   A 1 87  ? 102.342 88.468  110.435 1.00 69.22  ? 87  LEU   A CA  1 
ATOM   360  C  C   . LEU   A 1 87  ? 101.330 87.880  111.407 1.00 69.22  ? 87  LEU   A C   1 
ATOM   361  O  O   . LEU   A 1 87  ? 100.442 88.595  111.883 1.00 69.22  ? 87  LEU   A O   1 
ATOM   362  C  CB  . LEU   A 1 87  ? 102.429 87.623  109.163 1.00 69.22  ? 87  LEU   A CB  1 
ATOM   363  C  CG  . LEU   A 1 87  ? 101.132 87.010  108.627 1.00 69.22  ? 87  LEU   A CG  1 
ATOM   364  C  CD1 . LEU   A 1 87  ? 100.230 88.082  108.052 1.00 69.22  ? 87  LEU   A CD1 1 
ATOM   365  C  CD2 . LEU   A 1 87  ? 101.432 85.947  107.582 1.00 69.22  ? 87  LEU   A CD2 1 
ATOM   366  N  N   . PHE   A 1 88  ? 101.518 86.619  111.796 1.00 67.28  ? 88  PHE   A N   1 
ATOM   367  C  CA  . PHE   A 1 88  ? 100.556 85.938  112.656 1.00 67.28  ? 88  PHE   A CA  1 
ATOM   368  C  C   . PHE   A 1 88  ? 100.485 86.517  114.061 1.00 67.28  ? 88  PHE   A C   1 
ATOM   369  O  O   . PHE   A 1 88  ? 99.552  86.192  114.803 1.00 67.28  ? 88  PHE   A O   1 
ATOM   370  C  CB  . PHE   A 1 88  ? 100.880 84.443  112.737 1.00 67.28  ? 88  PHE   A CB  1 
ATOM   371  C  CG  . PHE   A 1 88  ? 100.504 83.676  111.502 1.00 67.28  ? 88  PHE   A CG  1 
ATOM   372  C  CD1 . PHE   A 1 88  ? 99.194  83.660  111.056 1.00 67.28  ? 88  PHE   A CD1 1 
ATOM   373  C  CD2 . PHE   A 1 88  ? 101.460 82.978  110.784 1.00 67.28  ? 88  PHE   A CD2 1 
ATOM   374  C  CE1 . PHE   A 1 88  ? 98.842  82.960  109.921 1.00 67.28  ? 88  PHE   A CE1 1 
ATOM   375  C  CE2 . PHE   A 1 88  ? 101.113 82.277  109.647 1.00 67.28  ? 88  PHE   A CE2 1 
ATOM   376  C  CZ  . PHE   A 1 88  ? 99.803  82.268  109.215 1.00 67.28  ? 88  PHE   A CZ  1 
ATOM   377  N  N   . GLY   A 1 89  ? 101.438 87.365  114.452 1.00 64.66  ? 89  GLY   A N   1 
ATOM   378  C  CA  . GLY   A 1 89  ? 101.376 87.956  115.774 1.00 64.66  ? 89  GLY   A CA  1 
ATOM   379  C  C   . GLY   A 1 89  ? 100.695 89.305  115.826 1.00 64.66  ? 89  GLY   A C   1 
ATOM   380  O  O   . GLY   A 1 89  ? 99.982  89.597  116.791 1.00 64.66  ? 89  GLY   A O   1 
ATOM   381  N  N   . SER   A 1 90  ? 100.897 90.146  114.812 1.00 68.27  ? 90  SER   A N   1 
ATOM   382  C  CA  . SER   A 1 90  ? 100.391 91.510  114.878 1.00 68.27  ? 90  SER   A CA  1 
ATOM   383  C  C   . SER   A 1 90  ? 99.616  91.930  113.634 1.00 68.27  ? 90  SER   A C   1 
ATOM   384  O  O   . SER   A 1 90  ? 98.695  92.746  113.732 1.00 68.27  ? 90  SER   A O   1 
ATOM   385  C  CB  . SER   A 1 90  ? 101.549 92.478  115.117 1.00 68.27  ? 90  SER   A CB  1 
ATOM   386  O  OG  . SER   A 1 90  ? 102.666 92.133  114.317 1.00 68.27  ? 90  SER   A OG  1 
ATOM   387  N  N   . GLY   A 1 91  ? 99.968  91.399  112.464 1.00 69.13  ? 91  GLY   A N   1 
ATOM   388  C  CA  . GLY   A 1 91  ? 99.375  91.897  111.239 1.00 69.13  ? 91  GLY   A CA  1 
ATOM   389  C  C   . GLY   A 1 91  ? 97.886  91.641  111.162 1.00 69.13  ? 91  GLY   A C   1 
ATOM   390  O  O   . GLY   A 1 91  ? 97.089  92.580  111.228 1.00 69.13  ? 91  GLY   A O   1 
ATOM   391  N  N   . LEU   A 1 92  ? 97.499  90.373  111.036 1.00 69.63  ? 92  LEU   A N   1 
ATOM   392  C  CA  . LEU   A 1 92  ? 96.079  90.033  111.033 1.00 69.63  ? 92  LEU   A CA  1 
ATOM   393  C  C   . LEU   A 1 92  ? 95.354  90.454  112.308 1.00 69.63  ? 92  LEU   A C   1 
ATOM   394  O  O   . LEU   A 1 92  ? 94.226  90.966  112.196 1.00 69.63  ? 92  LEU   A O   1 
ATOM   395  C  CB  . LEU   A 1 92  ? 95.911  88.531  110.770 1.00 69.63  ? 92  LEU   A CB  1 
ATOM   396  C  CG  . LEU   A 1 92  ? 96.322  88.067  109.371 1.00 69.63  ? 92  LEU   A CG  1 
ATOM   397  C  CD1 . LEU   A 1 92  ? 96.484  86.559  109.327 1.00 69.63  ? 92  LEU   A CD1 1 
ATOM   398  C  CD2 . LEU   A 1 92  ? 95.312  88.530  108.336 1.00 69.63  ? 92  LEU   A CD2 1 
ATOM   399  N  N   . PRO   A 1 93  ? 95.901  90.264  113.517 1.00 73.65  ? 93  PRO   A N   1 
ATOM   400  C  CA  . PRO   A 1 93  ? 95.186  90.754  114.711 1.00 73.65  ? 93  PRO   A CA  1 
ATOM   401  C  C   . PRO   A 1 93  ? 94.860  92.236  114.658 1.00 73.65  ? 93  PRO   A C   1 
ATOM   402  O  O   . PRO   A 1 93  ? 93.693  92.613  114.808 1.00 73.65  ? 93  PRO   A O   1 
ATOM   403  C  CB  . PRO   A 1 93  ? 96.155  90.414  115.849 1.00 73.65  ? 93  PRO   A CB  1 
ATOM   404  C  CG  . PRO   A 1 93  ? 96.875  89.223  115.358 1.00 73.65  ? 93  PRO   A CG  1 
ATOM   405  C  CD  . PRO   A 1 93  ? 97.076  89.457  113.893 1.00 73.65  ? 93  PRO   A CD  1 
ATOM   406  N  N   . VAL   A 1 94  ? 95.854  93.096  114.431 1.00 74.49  ? 94  VAL   A N   1 
ATOM   407  C  CA  . VAL   A 1 94  ? 95.563  94.524  114.331 1.00 74.49  ? 94  VAL   A CA  1 
ATOM   408  C  C   . VAL   A 1 94  ? 94.676  94.803  113.121 1.00 74.49  ? 94  VAL   A C   1 
ATOM   409  O  O   . VAL   A 1 94  ? 93.732  95.601  113.193 1.00 74.49  ? 94  VAL   A O   1 
ATOM   410  C  CB  . VAL   A 1 94  ? 96.869  95.338  114.293 1.00 74.49  ? 94  VAL   A CB  1 
ATOM   411  C  CG1 . VAL   A 1 94  ? 96.568  96.818  114.183 1.00 74.49  ? 94  VAL   A CG1 1 
ATOM   412  C  CG2 . VAL   A 1 94  ? 97.681  95.075  115.550 1.00 74.49  ? 94  VAL   A CG2 1 
ATOM   413  N  N   . PHE   A 1 95  ? 94.933  94.120  112.001 1.00 73.20  ? 95  PHE   A N   1 
ATOM   414  C  CA  . PHE   A 1 95  ? 94.119  94.336  110.807 1.00 73.20  ? 95  PHE   A CA  1 
ATOM   415  C  C   . PHE   A 1 95  ? 92.638  94.147  111.112 1.00 73.20  ? 95  PHE   A C   1 
ATOM   416  O  O   . PHE   A 1 95  ? 91.793  94.901  110.618 1.00 73.20  ? 95  PHE   A O   1 
ATOM   417  C  CB  . PHE   A 1 95  ? 94.565  93.395  109.688 1.00 73.20  ? 95  PHE   A CB  1 
ATOM   418  C  CG  . PHE   A 1 95  ? 93.844  93.607  108.390 1.00 73.20  ? 95  PHE   A CG  1 
ATOM   419  C  CD1 . PHE   A 1 95  ? 93.421  94.870  108.013 1.00 73.20  ? 95  PHE   A CD1 1 
ATOM   420  C  CD2 . PHE   A 1 95  ? 93.602  92.544  107.540 1.00 73.20  ? 95  PHE   A CD2 1 
ATOM   421  C  CE1 . PHE   A 1 95  ? 92.760  95.064  106.820 1.00 73.20  ? 95  PHE   A CE1 1 
ATOM   422  C  CE2 . PHE   A 1 95  ? 92.943  92.733  106.344 1.00 73.20  ? 95  PHE   A CE2 1 
ATOM   423  C  CZ  . PHE   A 1 95  ? 92.522  93.994  105.984 1.00 73.20  ? 95  PHE   A CZ  1 
ATOM   424  N  N   . PHE   A 1 96  ? 92.305  93.153  111.936 1.00 75.67  ? 96  PHE   A N   1 
ATOM   425  C  CA  . PHE   A 1 96  ? 90.934  93.035  112.423 1.00 75.67  ? 96  PHE   A CA  1 
ATOM   426  C  C   . PHE   A 1 96  ? 90.628  94.120  113.453 1.00 75.67  ? 96  PHE   A C   1 
ATOM   427  O  O   . PHE   A 1 96  ? 89.484  94.577  113.561 1.00 75.67  ? 96  PHE   A O   1 
ATOM   428  C  CB  . PHE   A 1 96  ? 90.716  91.630  113.001 1.00 75.67  ? 96  PHE   A CB  1 
ATOM   429  C  CG  . PHE   A 1 96  ? 89.301  91.348  113.460 1.00 75.67  ? 96  PHE   A CG  1 
ATOM   430  C  CD1 . PHE   A 1 96  ? 88.508  90.459  112.755 1.00 75.67  ? 96  PHE   A CD1 1 
ATOM   431  C  CD2 . PHE   A 1 96  ? 88.789  91.907  114.622 1.00 75.67  ? 96  PHE   A CD2 1 
ATOM   432  C  CE1 . PHE   A 1 96  ? 87.217  90.178  113.167 1.00 75.67  ? 96  PHE   A CE1 1 
ATOM   433  C  CE2 . PHE   A 1 96  ? 87.499  91.629  115.036 1.00 75.67  ? 96  PHE   A CE2 1 
ATOM   434  C  CZ  . PHE   A 1 96  ? 86.715  90.761  114.309 1.00 75.67  ? 96  PHE   A CZ  1 
ATOM   435  N  N   . LEU   A 1 97  ? 91.640  94.544  114.214 1.00 75.78  ? 97  LEU   A N   1 
ATOM   436  C  CA  . LEU   A 1 97  ? 91.403  95.392  115.380 1.00 75.78  ? 97  LEU   A CA  1 
ATOM   437  C  C   . LEU   A 1 97  ? 90.893  96.776  114.988 1.00 75.78  ? 97  LEU   A C   1 
ATOM   438  O  O   . LEU   A 1 97  ? 89.859  97.228  115.495 1.00 75.78  ? 97  LEU   A O   1 
ATOM   439  C  CB  . LEU   A 1 97  ? 92.686  95.498  116.205 1.00 75.78  ? 97  LEU   A CB  1 
ATOM   440  C  CG  . LEU   A 1 97  ? 92.643  96.146  117.586 1.00 75.78  ? 97  LEU   A CG  1 
ATOM   441  C  CD1 . LEU   A 1 97  ? 93.669  95.475  118.465 1.00 75.78  ? 97  LEU   A CD1 1 
ATOM   442  C  CD2 . LEU   A 1 97  ? 92.928  97.633  117.500 1.00 75.78  ? 97  LEU   A CD2 1 
ATOM   443  N  N   . GLU   A 1 98  ? 91.605  97.478  114.100 1.00 80.33  ? 98  GLU   A N   1 
ATOM   444  C  CA  . GLU   A 1 98  ? 91.080  98.803  113.752 1.00 80.33  ? 98  GLU   A CA  1 
ATOM   445  C  C   . GLU   A 1 98  ? 89.819  98.706  112.901 1.00 80.33  ? 98  GLU   A C   1 
ATOM   446  O  O   . GLU   A 1 98  ? 88.985  99.614  112.947 1.00 80.33  ? 98  GLU   A O   1 
ATOM   447  C  CB  . GLU   A 1 98  ? 92.085  99.746  113.060 1.00 80.33  ? 98  GLU   A CB  1 
ATOM   448  C  CG  . GLU   A 1 98  ? 92.546  99.422  111.647 1.00 80.33  ? 98  GLU   A CG  1 
ATOM   449  C  CD  . GLU   A 1 98  ? 93.715  98.488  111.631 1.00 80.33  ? 98  GLU   A CD  1 
ATOM   450  O  OE1 . GLU   A 1 98  ? 93.970  97.888  112.678 1.00 80.33  ? 98  GLU   A OE1 1 
ATOM   451  O  OE2 . GLU   A 1 98  ? 94.376  98.354  110.580 1.00 80.33  ? 98  GLU   A OE2 1 
ATOM   452  N  N   . ILE   A 1 99  ? 89.636  97.618  112.150 1.00 83.06  ? 99  ILE   A N   1 
ATOM   453  C  CA  . ILE   A 1 99  ? 88.381  97.439  111.420 1.00 83.06  ? 99  ILE   A CA  1 
ATOM   454  C  C   . ILE   A 1 99  ? 87.208  97.359  112.390 1.00 83.06  ? 99  ILE   A C   1 
ATOM   455  O  O   . ILE   A 1 99  ? 86.191  98.048  112.226 1.00 83.06  ? 99  ILE   A O   1 
ATOM   456  C  CB  . ILE   A 1 99  ? 88.448  96.195  110.515 1.00 83.06  ? 99  ILE   A CB  1 
ATOM   457  C  CG1 . ILE   A 1 99  ? 89.306  96.469  109.279 1.00 83.06  ? 99  ILE   A CG1 1 
ATOM   458  C  CG2 . ILE   A 1 99  ? 87.054  95.754  110.109 1.00 83.06  ? 99  ILE   A CG2 1 
ATOM   459  C  CD1 . ILE   A 1 99  ? 89.515  95.254  108.403 1.00 83.06  ? 99  ILE   A CD1 1 
ATOM   460  N  N   . ILE   A 1 100 ? 87.332  96.520  113.421 1.00 86.82  ? 100 ILE   A N   1 
ATOM   461  C  CA  . ILE   A 1 100 ? 86.233  96.356  114.366 1.00 86.82  ? 100 ILE   A CA  1 
ATOM   462  C  C   . ILE   A 1 100 ? 86.042  97.628  115.186 1.00 86.82  ? 100 ILE   A C   1 
ATOM   463  O  O   . ILE   A 1 100 ? 84.909  98.006  115.509 1.00 86.82  ? 100 ILE   A O   1 
ATOM   464  C  CB  . ILE   A 1 100 ? 86.456  95.112  115.252 1.00 86.82  ? 100 ILE   A CB  1 
ATOM   465  C  CG1 . ILE   A 1 100 ? 85.177  94.756  116.012 1.00 86.82  ? 100 ILE   A CG1 1 
ATOM   466  C  CG2 . ILE   A 1 100 ? 87.598  95.308  116.227 1.00 86.82  ? 100 ILE   A CG2 1 
ATOM   467  C  CD1 . ILE   A 1 100 ? 84.042  94.308  115.121 1.00 86.82  ? 100 ILE   A CD1 1 
ATOM   468  N  N   . ILE   A 1 101 ? 87.134  98.328  115.507 1.00 89.32  ? 101 ILE   A N   1 
ATOM   469  C  CA  . ILE   A 1 101 ? 87.006  99.592  116.227 1.00 89.32  ? 101 ILE   A CA  1 
ATOM   470  C  C   . ILE   A 1 101 ? 86.268  100.620 115.380 1.00 89.32  ? 101 ILE   A C   1 
ATOM   471  O  O   . ILE   A 1 101 ? 85.392  101.337 115.877 1.00 89.32  ? 101 ILE   A O   1 
ATOM   472  C  CB  . ILE   A 1 101 ? 88.388  100.106 116.666 1.00 89.32  ? 101 ILE   A CB  1 
ATOM   473  C  CG1 . ILE   A 1 101 ? 88.908  99.288  117.848 1.00 89.32  ? 101 ILE   A CG1 1 
ATOM   474  C  CG2 . ILE   A 1 101 ? 88.323  101.582 117.034 1.00 89.32  ? 101 ILE   A CG2 1 
ATOM   475  C  CD1 . ILE   A 1 101 ? 90.209  99.803  118.412 1.00 89.32  ? 101 ILE   A CD1 1 
ATOM   476  N  N   . GLY   A 1 102 ? 86.603  100.711 114.091 1.00 91.90  ? 102 GLY   A N   1 
ATOM   477  C  CA  . GLY   A 1 102 ? 85.911  101.645 113.221 1.00 91.90  ? 102 GLY   A CA  1 
ATOM   478  C  C   . GLY   A 1 102 ? 84.439  101.318 113.068 1.00 91.90  ? 102 GLY   A C   1 
ATOM   479  O  O   . GLY   A 1 102 ? 83.589  102.210 113.105 1.00 91.90  ? 102 GLY   A O   1 
ATOM   480  N  N   . GLN   A 1 103 ? 84.116  100.032 112.901 1.00 91.41  ? 103 GLN   A N   1 
ATOM   481  C  CA  . GLN   A 1 103 ? 82.711  99.660  112.771 1.00 91.41  ? 103 GLN   A CA  1 
ATOM   482  C  C   . GLN   A 1 103 ? 81.947  99.902  114.068 1.00 91.41  ? 103 GLN   A C   1 
ATOM   483  O  O   . GLN   A 1 103 ? 80.745  100.188 114.030 1.00 91.41  ? 103 GLN   A O   1 
ATOM   484  C  CB  . GLN   A 1 103 ? 82.581  98.202  112.320 1.00 91.41  ? 103 GLN   A CB  1 
ATOM   485  C  CG  . GLN   A 1 103 ? 82.648  97.165  113.429 1.00 91.41  ? 103 GLN   A CG  1 
ATOM   486  C  CD  . GLN   A 1 103 ? 81.297  96.897  114.066 1.00 91.41  ? 103 GLN   A CD  1 
ATOM   487  O  OE1 . GLN   A 1 103 ? 80.268  96.914  113.393 1.00 91.41  ? 103 GLN   A OE1 1 
ATOM   488  N  NE2 . GLN   A 1 103 ? 81.296  96.657  115.372 1.00 91.41  ? 103 GLN   A NE2 1 
ATOM   489  N  N   . TYR   A 1 104 ? 82.615  99.791  115.220 1.00 95.28  ? 104 TYR   A N   1 
ATOM   490  C  CA  . TYR   A 1 104 ? 81.947  100.082 116.484 1.00 95.28  ? 104 TYR   A CA  1 
ATOM   491  C  C   . TYR   A 1 104 ? 81.787  101.581 116.704 1.00 95.28  ? 104 TYR   A C   1 
ATOM   492  O  O   . TYR   A 1 104 ? 80.816  102.013 117.336 1.00 95.28  ? 104 TYR   A O   1 
ATOM   493  C  CB  . TYR   A 1 104 ? 82.720  99.454  117.644 1.00 95.28  ? 104 TYR   A CB  1 
ATOM   494  C  CG  . TYR   A 1 104 ? 82.133  99.744  119.008 1.00 95.28  ? 104 TYR   A CG  1 
ATOM   495  C  CD1 . TYR   A 1 104 ? 81.112  98.960  119.528 1.00 95.28  ? 104 TYR   A CD1 1 
ATOM   496  C  CD2 . TYR   A 1 104 ? 82.605  100.799 119.780 1.00 95.28  ? 104 TYR   A CD2 1 
ATOM   497  C  CE1 . TYR   A 1 104 ? 80.574  99.222  120.774 1.00 95.28  ? 104 TYR   A CE1 1 
ATOM   498  C  CE2 . TYR   A 1 104 ? 82.073  101.068 121.025 1.00 95.28  ? 104 TYR   A CE2 1 
ATOM   499  C  CZ  . TYR   A 1 104 ? 81.059  100.277 121.518 1.00 95.28  ? 104 TYR   A CZ  1 
ATOM   500  O  OH  . TYR   A 1 104 ? 80.527  100.542 122.759 1.00 95.28  ? 104 TYR   A OH  1 
ATOM   501  N  N   . THR   A 1 105 ? 82.720  102.384 116.197 1.00 99.22  ? 105 THR   A N   1 
ATOM   502  C  CA  . THR   A 1 105 ? 82.685  103.825 116.411 1.00 99.22  ? 105 THR   A CA  1 
ATOM   503  C  C   . THR   A 1 105 ? 81.901  104.566 115.339 1.00 99.22  ? 105 THR   A C   1 
ATOM   504  O  O   . THR   A 1 105 ? 81.215  105.546 115.656 1.00 99.22  ? 105 THR   A O   1 
ATOM   505  C  CB  . THR   A 1 105 ? 84.109  104.386 116.470 1.00 99.22  ? 105 THR   A CB  1 
ATOM   506  O  OG1 . THR   A 1 105 ? 84.834  103.980 115.302 1.00 99.22  ? 105 THR   A OG1 1 
ATOM   507  C  CG2 . THR   A 1 105 ? 84.831  103.885 117.713 1.00 99.22  ? 105 THR   A CG2 1 
ATOM   508  N  N   . SER   A 1 106 ? 81.985  104.119 114.085 1.00 99.78  ? 106 SER   A N   1 
ATOM   509  C  CA  . SER   A 1 106 ? 81.315  104.778 112.963 1.00 99.78  ? 106 SER   A CA  1 
ATOM   510  C  C   . SER   A 1 106 ? 81.698  106.254 112.887 1.00 99.78  ? 106 SER   A C   1 
ATOM   511  O  O   . SER   A 1 106 ? 80.855  107.129 112.678 1.00 99.78  ? 106 SER   A O   1 
ATOM   512  C  CB  . SER   A 1 106 ? 79.797  104.610 113.049 1.00 99.78  ? 106 SER   A CB  1 
ATOM   513  O  OG  . SER   A 1 106 ? 79.239  105.499 114.000 1.00 99.78  ? 106 SER   A OG  1 
ATOM   514  N  N   . GLU   A 1 107 ? 82.989  106.533 113.062 1.00 101.02 ? 107 GLU   A N   1 
ATOM   515  C  CA  . GLU   A 1 107 ? 83.492  107.897 113.103 1.00 101.02 ? 107 GLU   A CA  1 
ATOM   516  C  C   . GLU   A 1 107 ? 84.951  107.875 112.651 1.00 101.02 ? 107 GLU   A C   1 
ATOM   517  O  O   . GLU   A 1 107 ? 85.521  106.812 112.387 1.00 101.02 ? 107 GLU   A O   1 
ATOM   518  C  CB  . GLU   A 1 107 ? 83.286  108.488 114.507 1.00 101.02 ? 107 GLU   A CB  1 
ATOM   519  C  CG  . GLU   A 1 107 ? 83.531  109.983 114.645 1.00 101.02 ? 107 GLU   A CG  1 
ATOM   520  C  CD  . GLU   A 1 107 ? 83.411  110.459 116.078 1.00 101.02 ? 107 GLU   A CD  1 
ATOM   521  O  OE1 . GLU   A 1 107 ? 84.144  109.939 116.943 1.00 101.02 ? 107 GLU   A OE1 1 
ATOM   522  O  OE2 . GLU   A 1 107 ? 82.582  111.355 116.339 1.00 101.02 ? 107 GLU   A OE2 1 
ATOM   523  N  N   . GLY   A 1 108 ? 85.559  109.058 112.557 1.00 98.34  ? 108 GLY   A N   1 
ATOM   524  C  CA  . GLY   A 1 108 ? 86.860  109.180 111.932 1.00 98.34  ? 108 GLY   A CA  1 
ATOM   525  C  C   . GLY   A 1 108 ? 87.965  108.471 112.693 1.00 98.34  ? 108 GLY   A C   1 
ATOM   526  O  O   . GLY   A 1 108 ? 87.858  108.163 113.881 1.00 98.34  ? 108 GLY   A O   1 
ATOM   527  N  N   . GLY   A 1 109 ? 89.059  108.217 111.970 1.00 92.46  ? 109 GLY   A N   1 
ATOM   528  C  CA  . GLY   A 1 109 ? 90.161  107.456 112.539 1.00 92.46  ? 109 GLY   A CA  1 
ATOM   529  C  C   . GLY   A 1 109 ? 90.853  108.166 113.686 1.00 92.46  ? 109 GLY   A C   1 
ATOM   530  O  O   . GLY   A 1 109 ? 91.393  107.525 114.590 1.00 92.46  ? 109 GLY   A O   1 
ATOM   531  N  N   . ILE   A 1 110 ? 90.875  109.499 113.653 1.00 91.56  ? 110 ILE   A N   1 
ATOM   532  C  CA  . ILE   A 1 110 ? 91.453  110.241 114.769 1.00 91.56  ? 110 ILE   A CA  1 
ATOM   533  C  C   . ILE   A 1 110 ? 90.600  110.078 116.018 1.00 91.56  ? 110 ILE   A C   1 
ATOM   534  O  O   . ILE   A 1 110 ? 91.126  110.007 117.136 1.00 91.56  ? 110 ILE   A O   1 
ATOM   535  C  CB  . ILE   A 1 110 ? 91.634  111.723 114.392 1.00 91.56  ? 110 ILE   A CB  1 
ATOM   536  C  CG1 . ILE   A 1 110 ? 92.496  111.846 113.135 1.00 91.56  ? 110 ILE   A CG1 1 
ATOM   537  C  CG2 . ILE   A 1 110 ? 92.263  112.497 115.540 1.00 91.56  ? 110 ILE   A CG2 1 
ATOM   538  C  CD1 . ILE   A 1 110 ? 92.664  113.264 112.647 1.00 91.56  ? 110 ILE   A CD1 1 
ATOM   539  N  N   . THR   A 1 111 ? 89.279  110.009 115.857 1.00 96.40  ? 111 THR   A N   1 
ATOM   540  C  CA  . THR   A 1 111 ? 88.360  109.934 116.984 1.00 96.40  ? 111 THR   A CA  1 
ATOM   541  C  C   . THR   A 1 111 ? 87.893  108.519 117.306 1.00 96.40  ? 111 THR   A C   1 
ATOM   542  O  O   . THR   A 1 111 ? 87.237  108.322 118.337 1.00 96.40  ? 111 THR   A O   1 
ATOM   543  C  CB  . THR   A 1 111 ? 87.140  110.823 116.723 1.00 96.40  ? 111 THR   A CB  1 
ATOM   544  O  OG1 . THR   A 1 111 ? 86.534  110.447 115.481 1.00 96.40  ? 111 THR   A OG1 1 
ATOM   545  C  CG2 . THR   A 1 111 ? 87.550  112.287 116.660 1.00 96.40  ? 111 THR   A CG2 1 
ATOM   546  N  N   . CYS   A 1 112 ? 88.208  107.530 116.466 1.00 93.00  ? 112 CYS   A N   1 
ATOM   547  C  CA  . CYS   A 1 112 ? 87.842  106.157 116.799 1.00 93.00  ? 112 CYS   A CA  1 
ATOM   548  C  C   . CYS   A 1 112 ? 88.558  105.704 118.065 1.00 93.00  ? 112 CYS   A C   1 
ATOM   549  O  O   . CYS   A 1 112 ? 87.956  105.072 118.939 1.00 93.00  ? 112 CYS   A O   1 
ATOM   550  C  CB  . CYS   A 1 112 ? 88.155  105.215 115.636 1.00 93.00  ? 112 CYS   A CB  1 
ATOM   551  S  SG  . CYS   A 1 112 ? 89.907  104.980 115.288 1.00 93.00  ? 112 CYS   A SG  1 
ATOM   552  N  N   . TRP   A 1 113 ? 89.847  106.033 118.184 1.00 90.77  ? 113 TRP   A N   1 
ATOM   553  C  CA  . TRP   A 1 113 ? 90.576  105.735 119.412 1.00 90.77  ? 113 TRP   A CA  1 
ATOM   554  C  C   . TRP   A 1 113 ? 90.137  106.643 120.552 1.00 90.77  ? 113 TRP   A C   1 
ATOM   555  O  O   . TRP   A 1 113 ? 90.253  106.264 121.723 1.00 90.77  ? 113 TRP   A O   1 
ATOM   556  C  CB  . TRP   A 1 113 ? 92.081  105.863 119.179 1.00 90.77  ? 113 TRP   A CB  1 
ATOM   557  C  CG  . TRP   A 1 113 ? 92.716  104.593 118.714 1.00 90.77  ? 113 TRP   A CG  1 
ATOM   558  C  CD1 . TRP   A 1 113 ? 93.369  104.388 117.535 1.00 90.77  ? 113 TRP   A CD1 1 
ATOM   559  C  CD2 . TRP   A 1 113 ? 92.753  103.345 119.416 1.00 90.77  ? 113 TRP   A CD2 1 
ATOM   560  N  NE1 . TRP   A 1 113 ? 93.813  103.091 117.459 1.00 90.77  ? 113 TRP   A NE1 1 
ATOM   561  C  CE2 . TRP   A 1 113 ? 93.448  102.429 118.602 1.00 90.77  ? 113 TRP   A CE2 1 
ATOM   562  C  CE3 . TRP   A 1 113 ? 92.268  102.912 120.654 1.00 90.77  ? 113 TRP   A CE3 1 
ATOM   563  C  CZ2 . TRP   A 1 113 ? 93.668  101.108 118.985 1.00 90.77  ? 113 TRP   A CZ2 1 
ATOM   564  C  CZ3 . TRP   A 1 113 ? 92.489  101.600 121.032 1.00 90.77  ? 113 TRP   A CZ3 1 
ATOM   565  C  CH2 . TRP   A 1 113 ? 93.184  100.714 120.201 1.00 90.77  ? 113 TRP   A CH2 1 
ATOM   566  N  N   . GLU   A 1 114 ? 89.643  107.841 120.233 1.00 94.79  ? 114 GLU   A N   1 
ATOM   567  C  CA  . GLU   A 1 114 ? 89.108  108.722 121.265 1.00 94.79  ? 114 GLU   A CA  1 
ATOM   568  C  C   . GLU   A 1 114 ? 87.882  108.106 121.926 1.00 94.79  ? 114 GLU   A C   1 
ATOM   569  O  O   . GLU   A 1 114 ? 87.701  108.214 123.145 1.00 94.79  ? 114 GLU   A O   1 
ATOM   570  C  CB  . GLU   A 1 114 ? 88.769  110.086 120.663 1.00 94.79  ? 114 GLU   A CB  1 
ATOM   571  C  CG  . GLU   A 1 114 ? 88.255  111.107 121.665 1.00 94.79  ? 114 GLU   A CG  1 
ATOM   572  C  CD  . GLU   A 1 114 ? 89.324  111.558 122.640 1.00 94.79  ? 114 GLU   A CD  1 
ATOM   573  O  OE1 . GLU   A 1 114 ? 90.521  111.486 122.290 1.00 94.79  ? 114 GLU   A OE1 1 
ATOM   574  O  OE2 . GLU   A 1 114 ? 88.967  111.990 123.755 1.00 94.79  ? 114 GLU   A OE2 1 
ATOM   575  N  N   . LYS   A 1 115 ? 87.020  107.468 121.132 1.00 93.87  ? 115 LYS   A N   1 
ATOM   576  C  CA  . LYS   A 1 115 ? 85.854  106.793 121.697 1.00 93.87  ? 115 LYS   A CA  1 
ATOM   577  C  C   . LYS   A 1 115 ? 86.267  105.650 122.620 1.00 93.87  ? 115 LYS   A C   1 
ATOM   578  O  O   . LYS   A 1 115 ? 85.659  105.441 123.676 1.00 93.87  ? 115 LYS   A O   1 
ATOM   579  C  CB  . LYS   A 1 115 ? 84.935  106.283 120.587 1.00 93.87  ? 115 LYS   A CB  1 
ATOM   580  C  CG  . LYS   A 1 115 ? 84.068  107.358 119.953 1.00 93.87  ? 115 LYS   A CG  1 
ATOM   581  C  CD  . LYS   A 1 115 ? 83.061  106.752 118.989 1.00 93.87  ? 115 LYS   A CD  1 
ATOM   582  C  CE  . LYS   A 1 115 ? 82.169  107.813 118.368 1.00 93.87  ? 115 LYS   A CE  1 
ATOM   583  N  NZ  . LYS   A 1 115 ? 81.239  108.407 119.366 1.00 93.87  ? 115 LYS   A NZ  1 
ATOM   584  N  N   . ILE   A 1 116 ? 87.295  104.889 122.231 1.00 91.77  ? 116 ILE   A N   1 
ATOM   585  C  CA  . ILE   A 1 116 ? 87.754  103.776 123.061 1.00 91.77  ? 116 ILE   A CA  1 
ATOM   586  C  C   . ILE   A 1 116 ? 88.276  104.282 124.401 1.00 91.77  ? 116 ILE   A C   1 
ATOM   587  O  O   . ILE   A 1 116 ? 87.958  103.724 125.458 1.00 91.77  ? 116 ILE   A O   1 
ATOM   588  C  CB  . ILE   A 1 116 ? 88.822  102.952 122.318 1.00 91.77  ? 116 ILE   A CB  1 
ATOM   589  C  CG1 . ILE   A 1 116 ? 88.381  102.671 120.883 1.00 91.77  ? 116 ILE   A CG1 1 
ATOM   590  C  CG2 . ILE   A 1 116 ? 89.103  101.656 123.056 1.00 91.77  ? 116 ILE   A CG2 1 
ATOM   591  C  CD1 . ILE   A 1 116 ? 87.206  101.731 120.782 1.00 91.77  ? 116 ILE   A CD1 1 
ATOM   592  N  N   . CYS   A 1 117 ? 89.087  105.342 124.380 1.00 96.48  ? 117 CYS   A N   1 
ATOM   593  C  CA  . CYS   A 1 117 ? 89.643  105.914 125.593 1.00 96.48  ? 117 CYS   A CA  1 
ATOM   594  C  C   . CYS   A 1 117 ? 89.931  107.385 125.332 1.00 96.48  ? 117 CYS   A C   1 
ATOM   595  O  O   . CYS   A 1 117 ? 90.408  107.723 124.237 1.00 96.48  ? 117 CYS   A O   1 
ATOM   596  C  CB  . CYS   A 1 117 ? 90.921  105.201 126.033 1.00 96.48  ? 117 CYS   A CB  1 
ATOM   597  S  SG  . CYS   A 1 117 ? 92.108  104.923 124.702 1.00 96.48  ? 117 CYS   A SG  1 
ATOM   598  N  N   . PRO   A 1 118 ? 89.647  108.271 126.291 1.00 97.65  ? 118 PRO   A N   1 
ATOM   599  C  CA  . PRO   A 1 118 ? 89.932  109.699 126.067 1.00 97.65  ? 118 PRO   A CA  1 
ATOM   600  C  C   . PRO   A 1 118 ? 91.391  109.978 125.754 1.00 97.65  ? 118 PRO   A C   1 
ATOM   601  O  O   . PRO   A 1 118 ? 91.688  110.853 124.930 1.00 97.65  ? 118 PRO   A O   1 
ATOM   602  C  CB  . PRO   A 1 118 ? 89.496  110.351 127.386 1.00 97.65  ? 118 PRO   A CB  1 
ATOM   603  C  CG  . PRO   A 1 118 ? 88.519  109.391 127.981 1.00 97.65  ? 118 PRO   A CG  1 
ATOM   604  C  CD  . PRO   A 1 118 ? 89.006  108.030 127.594 1.00 97.65  ? 118 PRO   A CD  1 
ATOM   605  N  N   . LEU   A 1 119 ? 92.313  109.256 126.385 1.00 92.96  ? 119 LEU   A N   1 
ATOM   606  C  CA  . LEU   A 1 119 ? 93.731  109.427 126.114 1.00 92.96  ? 119 LEU   A CA  1 
ATOM   607  C  C   . LEU   A 1 119 ? 94.128  108.633 124.871 1.00 92.96  ? 119 LEU   A C   1 
ATOM   608  O  O   . LEU   A 1 119 ? 93.293  108.046 124.179 1.00 92.96  ? 119 LEU   A O   1 
ATOM   609  C  CB  . LEU   A 1 119 ? 94.563  108.999 127.322 1.00 92.96  ? 119 LEU   A CB  1 
ATOM   610  C  CG  . LEU   A 1 119 ? 94.761  110.001 128.463 1.00 92.96  ? 119 LEU   A CG  1 
ATOM   611  C  CD1 . LEU   A 1 119 ? 93.496  110.157 129.294 1.00 92.96  ? 119 LEU   A CD1 1 
ATOM   612  C  CD2 . LEU   A 1 119 ? 95.931  109.580 129.340 1.00 92.96  ? 119 LEU   A CD2 1 
ATOM   613  N  N   . PHE   A 1 120 ? 95.427  108.628 124.583 1.00 84.82  ? 120 PHE   A N   1 
ATOM   614  C  CA  . PHE   A 1 120 ? 96.038  107.855 123.506 1.00 84.82  ? 120 PHE   A CA  1 
ATOM   615  C  C   . PHE   A 1 120 ? 95.538  108.250 122.121 1.00 84.82  ? 120 PHE   A C   1 
ATOM   616  O  O   . PHE   A 1 120 ? 95.651  107.457 121.179 1.00 84.82  ? 120 PHE   A O   1 
ATOM   617  C  CB  . PHE   A 1 120 ? 95.847  106.349 123.724 1.00 84.82  ? 120 PHE   A CB  1 
ATOM   618  C  CG  . PHE   A 1 120 ? 96.538  105.825 124.950 1.00 84.82  ? 120 PHE   A CG  1 
ATOM   619  C  CD1 . PHE   A 1 120 ? 97.877  105.473 124.910 1.00 84.82  ? 120 PHE   A CD1 1 
ATOM   620  C  CD2 . PHE   A 1 120 ? 95.853  105.700 126.147 1.00 84.82  ? 120 PHE   A CD2 1 
ATOM   621  C  CE1 . PHE   A 1 120 ? 98.516  104.995 126.039 1.00 84.82  ? 120 PHE   A CE1 1 
ATOM   622  C  CE2 . PHE   A 1 120 ? 96.488  105.224 127.278 1.00 84.82  ? 120 PHE   A CE2 1 
ATOM   623  C  CZ  . PHE   A 1 120 ? 97.821  104.872 127.224 1.00 84.82  ? 120 PHE   A CZ  1 
ATOM   624  N  N   . SER   A 1 121 ? 94.990  109.458 121.965 1.00 82.74  ? 121 SER   A N   1 
ATOM   625  C  CA  . SER   A 1 121 ? 94.722  109.989 120.633 1.00 82.74  ? 121 SER   A CA  1 
ATOM   626  C  C   . SER   A 1 121 ? 96.005  110.318 119.883 1.00 82.74  ? 121 SER   A C   1 
ATOM   627  O  O   . SER   A 1 121 ? 95.957  110.590 118.673 1.00 82.74  ? 121 SER   A O   1 
ATOM   628  C  CB  . SER   A 1 121 ? 93.837  111.232 120.731 1.00 82.74  ? 121 SER   A CB  1 
ATOM   629  O  OG  . SER   A 1 121 ? 92.644  110.951 121.441 1.00 82.74  ? 121 SER   A OG  1 
ATOM   630  N  N   . GLY   A 1 122 ? 97.143  110.309 120.580 1.00 77.08  ? 122 GLY   A N   1 
ATOM   631  C  CA  . GLY   A 1 122 ? 98.417  110.440 119.907 1.00 77.08  ? 122 GLY   A CA  1 
ATOM   632  C  C   . GLY   A 1 122 ? 98.633  109.366 118.865 1.00 77.08  ? 122 GLY   A C   1 
ATOM   633  O  O   . GLY   A 1 122 ? 99.365  109.577 117.902 1.00 77.08  ? 122 GLY   A O   1 
ATOM   634  N  N   . ILE   A 1 123 ? 97.983  108.212 119.028 1.00 74.81  ? 123 ILE   A N   1 
ATOM   635  C  CA  . ILE   A 1 123 ? 98.025  107.189 117.987 1.00 74.81  ? 123 ILE   A CA  1 
ATOM   636  C  C   . ILE   A 1 123 ? 97.435  107.725 116.690 1.00 74.81  ? 123 ILE   A C   1 
ATOM   637  O  O   . ILE   A 1 123 ? 98.052  107.628 115.621 1.00 74.81  ? 123 ILE   A O   1 
ATOM   638  C  CB  . ILE   A 1 123 ? 97.292  105.921 118.460 1.00 74.81  ? 123 ILE   A CB  1 
ATOM   639  C  CG1 . ILE   A 1 123 ? 98.064  105.251 119.599 1.00 74.81  ? 123 ILE   A CG1 1 
ATOM   640  C  CG2 . ILE   A 1 123 ? 97.078  104.970 117.299 1.00 74.81  ? 123 ILE   A CG2 1 
ATOM   641  C  CD1 . ILE   A 1 123 ? 97.275  104.198 120.336 1.00 74.81  ? 123 ILE   A CD1 1 
ATOM   642  N  N   . GLY   A 1 124 ? 96.241  108.316 116.763 1.00 71.37  ? 124 GLY   A N   1 
ATOM   643  C  CA  . GLY   A 1 124 ? 95.622  108.858 115.564 1.00 71.37  ? 124 GLY   A CA  1 
ATOM   644  C  C   . GLY   A 1 124 ? 96.404  110.018 114.978 1.00 71.37  ? 124 GLY   A C   1 
ATOM   645  O  O   . GLY   A 1 124 ? 96.565  110.126 113.757 1.00 71.37  ? 124 GLY   A O   1 
ATOM   646  N  N   . TYR   A 1 125 ? 96.895  110.908 115.842 1.00 76.89  ? 125 TYR   A N   1 
ATOM   647  C  CA  . TYR   A 1 125 ? 97.674  112.039 115.341 1.00 76.89  ? 125 TYR   A CA  1 
ATOM   648  C  C   . TYR   A 1 125 ? 98.984  111.589 114.701 1.00 76.89  ? 125 TYR   A C   1 
ATOM   649  O  O   . TYR   A 1 125 ? 99.383  112.130 113.663 1.00 76.89  ? 125 TYR   A O   1 
ATOM   650  C  CB  . TYR   A 1 125 ? 97.920  113.051 116.457 1.00 76.89  ? 125 TYR   A CB  1 
ATOM   651  C  CG  . TYR   A 1 125 ? 96.655  113.757 116.882 1.00 76.89  ? 125 TYR   A CG  1 
ATOM   652  C  CD1 . TYR   A 1 125 ? 95.991  114.606 116.010 1.00 76.89  ? 125 TYR   A CD1 1 
ATOM   653  C  CD2 . TYR   A 1 125 ? 96.115  113.563 118.143 1.00 76.89  ? 125 TYR   A CD2 1 
ATOM   654  C  CE1 . TYR   A 1 125 ? 94.830  115.250 116.385 1.00 76.89  ? 125 TYR   A CE1 1 
ATOM   655  C  CE2 . TYR   A 1 125 ? 94.951  114.200 118.527 1.00 76.89  ? 125 TYR   A CE2 1 
ATOM   656  C  CZ  . TYR   A 1 125 ? 94.315  115.044 117.645 1.00 76.89  ? 125 TYR   A CZ  1 
ATOM   657  O  OH  . TYR   A 1 125 ? 93.157  115.683 118.025 1.00 76.89  ? 125 TYR   A OH  1 
ATOM   658  N  N   . ALA   A 1 126 ? 99.656  110.596 115.283 1.00 70.71  ? 126 ALA   A N   1 
ATOM   659  C  CA  . ALA   A 1 126 ? 100.849 110.046 114.658 1.00 70.71  ? 126 ALA   A CA  1 
ATOM   660  C  C   . ALA   A 1 126 ? 100.513 109.382 113.333 1.00 70.71  ? 126 ALA   A C   1 
ATOM   661  O  O   . ALA   A 1 126 ? 101.289 109.472 112.379 1.00 70.71  ? 126 ALA   A O   1 
ATOM   662  C  CB  . ALA   A 1 126 ? 101.530 109.055 115.600 1.00 70.71  ? 126 ALA   A CB  1 
ATOM   663  N  N   . SER   A 1 127 ? 99.359  108.715 113.250 1.00 65.68  ? 127 SER   A N   1 
ATOM   664  C  CA  . SER   A 1 127 ? 98.963  108.100 111.987 1.00 65.68  ? 127 SER   A CA  1 
ATOM   665  C  C   . SER   A 1 127 ? 98.751  109.148 110.902 1.00 65.68  ? 127 SER   A C   1 
ATOM   666  O  O   . SER   A 1 127 ? 99.189  108.963 109.759 1.00 65.68  ? 127 SER   A O   1 
ATOM   667  C  CB  . SER   A 1 127 ? 97.697  107.268 112.180 1.00 65.68  ? 127 SER   A CB  1 
ATOM   668  O  OG  . SER   A 1 127 ? 96.654  108.046 112.733 1.00 65.68  ? 127 SER   A OG  1 
ATOM   669  N  N   . VAL   A 1 128 ? 98.079  110.254 111.233 1.00 65.60  ? 128 VAL   A N   1 
ATOM   670  C  CA  . VAL   A 1 128 ? 97.826  111.271 110.214 1.00 65.60  ? 128 VAL   A CA  1 
ATOM   671  C  C   . VAL   A 1 128 ? 99.123  111.973 109.819 1.00 65.60  ? 128 VAL   A C   1 
ATOM   672  O  O   . VAL   A 1 128 ? 99.336  112.287 108.642 1.00 65.60  ? 128 VAL   A O   1 
ATOM   673  C  CB  . VAL   A 1 128 ? 96.736  112.266 110.664 1.00 65.60  ? 128 VAL   A CB  1 
ATOM   674  C  CG1 . VAL   A 1 128 ? 95.475  111.520 111.069 1.00 65.60  ? 128 VAL   A CG1 1 
ATOM   675  C  CG2 . VAL   A 1 128 ? 97.217  113.175 111.777 1.00 65.60  ? 128 VAL   A CG2 1 
ATOM   676  N  N   . VAL   A 1 129 ? 100.022 112.211 110.779 1.00 62.28  ? 129 VAL   A N   1 
ATOM   677  C  CA  . VAL   A 1 129 ? 101.315 112.795 110.430 1.00 62.28  ? 129 VAL   A CA  1 
ATOM   678  C  C   . VAL   A 1 129 ? 102.109 111.840 109.545 1.00 62.28  ? 129 VAL   A C   1 
ATOM   679  O  O   . VAL   A 1 129 ? 102.759 112.260 108.578 1.00 62.28  ? 129 VAL   A O   1 
ATOM   680  C  CB  . VAL   A 1 129 ? 102.094 113.179 111.701 1.00 62.28  ? 129 VAL   A CB  1 
ATOM   681  C  CG1 . VAL   A 1 129 ? 103.511 113.593 111.352 1.00 62.28  ? 129 VAL   A CG1 1 
ATOM   682  C  CG2 . VAL   A 1 129 ? 101.385 114.305 112.434 1.00 62.28  ? 129 VAL   A CG2 1 
ATOM   683  N  N   . ILE   A 1 130 ? 102.058 110.542 109.849 1.00 61.10  ? 130 ILE   A N   1 
ATOM   684  C  CA  . ILE   A 1 130 ? 102.774 109.551 109.056 1.00 61.10  ? 130 ILE   A CA  1 
ATOM   685  C  C   . ILE   A 1 130 ? 102.241 109.515 107.632 1.00 61.10  ? 130 ILE   A C   1 
ATOM   686  O  O   . ILE   A 1 130 ? 103.015 109.475 106.672 1.00 61.10  ? 130 ILE   A O   1 
ATOM   687  C  CB  . ILE   A 1 130 ? 102.685 108.168 109.727 1.00 61.10  ? 130 ILE   A CB  1 
ATOM   688  C  CG1 . ILE   A 1 130 ? 103.708 108.055 110.855 1.00 61.10  ? 130 ILE   A CG1 1 
ATOM   689  C  CG2 . ILE   A 1 130 ? 102.903 107.063 108.713 1.00 61.10  ? 130 ILE   A CG2 1 
ATOM   690  C  CD1 . ILE   A 1 130 ? 103.452 106.897 111.789 1.00 61.10  ? 130 ILE   A CD1 1 
ATOM   691  N  N   . VAL   A 1 131 ? 100.917 109.528 107.466 1.00 58.66  ? 131 VAL   A N   1 
ATOM   692  C  CA  . VAL   A 1 131 ? 100.361 109.466 106.115 1.00 58.66  ? 131 VAL   A CA  1 
ATOM   693  C  C   . VAL   A 1 131 ? 100.653 110.758 105.353 1.00 58.66  ? 131 VAL   A C   1 
ATOM   694  O  O   . VAL   A 1 131 ? 100.933 110.732 104.145 1.00 58.66  ? 131 VAL   A O   1 
ATOM   695  C  CB  . VAL   A 1 131 ? 98.856  109.131 106.156 1.00 58.66  ? 131 VAL   A CB  1 
ATOM   696  C  CG1 . VAL   A 1 131 ? 98.029  110.291 106.676 1.00 58.66  ? 131 VAL   A CG1 1 
ATOM   697  C  CG2 . VAL   A 1 131 ? 98.371  108.697 104.782 1.00 58.66  ? 131 VAL   A CG2 1 
ATOM   698  N  N   . SER   A 1 132 ? 100.622 111.905 106.045 1.00 57.03  ? 132 SER   A N   1 
ATOM   699  C  CA  . SER   A 1 132 ? 100.936 113.172 105.392 1.00 57.03  ? 132 SER   A CA  1 
ATOM   700  C  C   . SER   A 1 132 ? 102.382 113.205 104.916 1.00 57.03  ? 132 SER   A C   1 
ATOM   701  O  O   . SER   A 1 132 ? 102.668 113.685 103.814 1.00 57.03  ? 132 SER   A O   1 
ATOM   702  C  CB  . SER   A 1 132 ? 100.659 114.337 106.341 1.00 57.03  ? 132 SER   A CB  1 
ATOM   703  O  OG  . SER   A 1 132 ? 99.270  114.512 106.548 1.00 57.03  ? 132 SER   A OG  1 
ATOM   704  N  N   . LEU   A 1 133 ? 103.309 112.705 105.732 1.00 53.79  ? 133 LEU   A N   1 
ATOM   705  C  CA  . LEU   A 1 133 ? 104.706 112.650 105.322 1.00 53.79  ? 133 LEU   A CA  1 
ATOM   706  C  C   . LEU   A 1 133 ? 105.001 111.491 104.380 1.00 53.79  ? 133 LEU   A C   1 
ATOM   707  O  O   . LEU   A 1 133 ? 106.065 111.479 103.754 1.00 53.79  ? 133 LEU   A O   1 
ATOM   708  C  CB  . LEU   A 1 133 ? 105.615 112.556 106.549 1.00 53.79  ? 133 LEU   A CB  1 
ATOM   709  C  CG  . LEU   A 1 133 ? 105.542 113.720 107.540 1.00 53.79  ? 133 LEU   A CG  1 
ATOM   710  C  CD1 . LEU   A 1 133 ? 106.746 113.715 108.467 1.00 53.79  ? 133 LEU   A CD1 1 
ATOM   711  C  CD2 . LEU   A 1 133 ? 105.433 115.051 106.808 1.00 53.79  ? 133 LEU   A CD2 1 
ATOM   712  N  N   . LEU   A 1 134 ? 104.090 110.523 104.271 1.00 53.11  ? 134 LEU   A N   1 
ATOM   713  C  CA  . LEU   A 1 134 ? 104.289 109.390 103.377 1.00 53.11  ? 134 LEU   A CA  1 
ATOM   714  C  C   . LEU   A 1 134 ? 103.848 109.717 101.959 1.00 53.11  ? 134 LEU   A C   1 
ATOM   715  O  O   . LEU   A 1 134 ? 104.497 109.293 100.996 1.00 53.11  ? 134 LEU   A O   1 
ATOM   716  C  CB  . LEU   A 1 134 ? 103.526 108.174 103.905 1.00 53.11  ? 134 LEU   A CB  1 
ATOM   717  C  CG  . LEU   A 1 134 ? 103.200 107.046 102.923 1.00 53.11  ? 134 LEU   A CG  1 
ATOM   718  C  CD1 . LEU   A 1 134 ? 104.461 106.323 102.483 1.00 53.11  ? 134 LEU   A CD1 1 
ATOM   719  C  CD2 . LEU   A 1 134 ? 102.205 106.073 103.533 1.00 53.11  ? 134 LEU   A CD2 1 
ATOM   720  N  N   . ASN   A 1 135 ? 102.750 110.466 101.817 1.00 55.95  ? 135 ASN   A N   1 
ATOM   721  C  CA  . ASN   A 1 135 ? 102.270 110.840 100.489 1.00 55.95  ? 135 ASN   A CA  1 
ATOM   722  C  C   . ASN   A 1 135 ? 103.342 111.573 99.693  1.00 55.95  ? 135 ASN   A C   1 
ATOM   723  O  O   . ASN   A 1 135 ? 103.486 111.363 98.479  1.00 55.95  ? 135 ASN   A O   1 
ATOM   724  C  CB  . ASN   A 1 135 ? 101.022 111.714 100.612 1.00 55.95  ? 135 ASN   A CB  1 
ATOM   725  C  CG  . ASN   A 1 135 ? 99.805  110.934 101.048 1.00 55.95  ? 135 ASN   A CG  1 
ATOM   726  O  OD1 . ASN   A 1 135 ? 98.843  111.503 101.559 1.00 55.95  ? 135 ASN   A OD1 1 
ATOM   727  N  ND2 . ASN   A 1 135 ? 99.832  109.624 100.835 1.00 55.95  ? 135 ASN   A ND2 1 
ATOM   728  N  N   . VAL   A 1 136 ? 104.113 112.427 100.371 1.00 52.86  ? 136 VAL   A N   1 
ATOM   729  C  CA  . VAL   A 1 136 ? 105.048 113.316 99.688  1.00 52.86  ? 136 VAL   A CA  1 
ATOM   730  C  C   . VAL   A 1 136 ? 106.058 112.516 98.876  1.00 52.86  ? 136 VAL   A C   1 
ATOM   731  O  O   . VAL   A 1 136 ? 106.288 112.797 97.695  1.00 52.86  ? 136 VAL   A O   1 
ATOM   732  C  CB  . VAL   A 1 136 ? 105.741 114.243 100.702 1.00 52.86  ? 136 VAL   A CB  1 
ATOM   733  C  CG1 . VAL   A 1 136 ? 106.836 115.040 100.026 1.00 52.86  ? 136 VAL   A CG1 1 
ATOM   734  C  CG2 . VAL   A 1 136 ? 104.724 115.169 101.352 1.00 52.86  ? 136 VAL   A CG2 1 
ATOM   735  N  N   . TYR   A 1 137 ? 106.674 111.504 99.487  1.00 56.37  ? 137 TYR   A N   1 
ATOM   736  C  CA  . TYR   A 1 137 ? 107.624 110.699 98.733  1.00 56.37  ? 137 TYR   A CA  1 
ATOM   737  C  C   . TYR   A 1 137 ? 106.982 109.486 98.078  1.00 56.37  ? 137 TYR   A C   1 
ATOM   738  O  O   . TYR   A 1 137 ? 107.652 108.798 97.302  1.00 56.37  ? 137 TYR   A O   1 
ATOM   739  C  CB  . TYR   A 1 137 ? 108.789 110.226 99.611  1.00 56.37  ? 137 TYR   A CB  1 
ATOM   740  C  CG  . TYR   A 1 137 ? 108.423 109.293 100.741 1.00 56.37  ? 137 TYR   A CG  1 
ATOM   741  C  CD1 . TYR   A 1 137 ? 108.081 109.774 101.996 1.00 56.37  ? 137 TYR   A CD1 1 
ATOM   742  C  CD2 . TYR   A 1 137 ? 108.442 107.918 100.550 1.00 56.37  ? 137 TYR   A CD2 1 
ATOM   743  C  CE1 . TYR   A 1 137 ? 107.758 108.907 103.026 1.00 56.37  ? 137 TYR   A CE1 1 
ATOM   744  C  CE2 . TYR   A 1 137 ? 108.119 107.049 101.566 1.00 56.37  ? 137 TYR   A CE2 1 
ATOM   745  C  CZ  . TYR   A 1 137 ? 107.779 107.545 102.803 1.00 56.37  ? 137 TYR   A CZ  1 
ATOM   746  O  OH  . TYR   A 1 137 ? 107.459 106.673 103.817 1.00 56.37  ? 137 TYR   A OH  1 
ATOM   747  N  N   . TYR   A 1 138 ? 105.711 109.198 98.369  1.00 57.69  ? 138 TYR   A N   1 
ATOM   748  C  CA  . TYR   A 1 138 ? 105.056 108.087 97.697  1.00 57.69  ? 138 TYR   A CA  1 
ATOM   749  C  C   . TYR   A 1 138 ? 104.496 108.499 96.345  1.00 57.69  ? 138 TYR   A C   1 
ATOM   750  O  O   . TYR   A 1 138 ? 104.181 107.635 95.521  1.00 57.69  ? 138 TYR   A O   1 
ATOM   751  C  CB  . TYR   A 1 138 ? 103.942 107.519 98.579  1.00 57.69  ? 138 TYR   A CB  1 
ATOM   752  C  CG  . TYR   A 1 138 ? 103.601 106.083 98.266  1.00 57.69  ? 138 TYR   A CG  1 
ATOM   753  C  CD1 . TYR   A 1 138 ? 104.598 105.123 98.156  1.00 57.69  ? 138 TYR   A CD1 1 
ATOM   754  C  CD2 . TYR   A 1 138 ? 102.287 105.686 98.076  1.00 57.69  ? 138 TYR   A CD2 1 
ATOM   755  C  CE1 . TYR   A 1 138 ? 104.296 103.812 97.868  1.00 57.69  ? 138 TYR   A CE1 1 
ATOM   756  C  CE2 . TYR   A 1 138 ? 101.976 104.375 97.787  1.00 57.69  ? 138 TYR   A CE2 1 
ATOM   757  C  CZ  . TYR   A 1 138 ? 102.985 103.443 97.684  1.00 57.69  ? 138 TYR   A CZ  1 
ATOM   758  O  OH  . TYR   A 1 138 ? 102.684 102.134 97.396  1.00 57.69  ? 138 TYR   A OH  1 
ATOM   759  N  N   . ILE   A 1 139 ? 104.361 109.802 96.101  1.00 59.46  ? 139 ILE   A N   1 
ATOM   760  C  CA  . ILE   A 1 139 ? 103.905 110.250 94.790  1.00 59.46  ? 139 ILE   A CA  1 
ATOM   761  C  C   . ILE   A 1 139 ? 105.064 110.511 93.826  1.00 59.46  ? 139 ILE   A C   1 
ATOM   762  O  O   . ILE   A 1 139 ? 104.858 110.497 92.605  1.00 59.46  ? 139 ILE   A O   1 
ATOM   763  C  CB  . ILE   A 1 139 ? 103.015 111.497 94.938  1.00 59.46  ? 139 ILE   A CB  1 
ATOM   764  C  CG1 . ILE   A 1 139 ? 102.316 111.827 93.619  1.00 59.46  ? 139 ILE   A CG1 1 
ATOM   765  C  CG2 . ILE   A 1 139 ? 103.833 112.685 95.414  1.00 59.46  ? 139 ILE   A CG2 1 
ATOM   766  C  CD1 . ILE   A 1 139 ? 101.195 112.823 93.762  1.00 59.46  ? 139 ILE   A CD1 1 
ATOM   767  N  N   . VAL   A 1 140 ? 106.283 110.717 94.332  1.00 56.30  ? 140 VAL   A N   1 
ATOM   768  C  CA  . VAL   A 1 140 ? 107.422 110.975 93.452  1.00 56.30  ? 140 VAL   A CA  1 
ATOM   769  C  C   . VAL   A 1 140 ? 107.814 109.720 92.675  1.00 56.30  ? 140 VAL   A C   1 
ATOM   770  O  O   . VAL   A 1 140 ? 108.273 109.803 91.522  1.00 56.30  ? 140 VAL   A O   1 
ATOM   771  C  CB  . VAL   A 1 140 ? 108.602 111.530 94.270  1.00 56.30  ? 140 VAL   A CB  1 
ATOM   772  C  CG1 . VAL   A 1 140 ? 109.747 111.917 93.359  1.00 56.30  ? 140 VAL   A CG1 1 
ATOM   773  C  CG2 . VAL   A 1 140 ? 108.154 112.724 95.089  1.00 56.30  ? 140 VAL   A CG2 1 
ATOM   774  N  N   . ILE   A 1 141 ? 107.660 108.544 93.285  1.00 59.67  ? 141 ILE   A N   1 
ATOM   775  C  CA  . ILE   A 1 141 ? 107.901 107.304 92.555  1.00 59.67  ? 141 ILE   A CA  1 
ATOM   776  C  C   . ILE   A 1 141 ? 106.920 107.177 91.395  1.00 59.67  ? 141 ILE   A C   1 
ATOM   777  O  O   . ILE   A 1 141 ? 107.296 106.780 90.287  1.00 59.67  ? 141 ILE   A O   1 
ATOM   778  C  CB  . ILE   A 1 141 ? 107.845 106.093 93.508  1.00 59.67  ? 141 ILE   A CB  1 
ATOM   779  C  CG1 . ILE   A 1 141 ? 106.467 105.951 94.152  1.00 59.67  ? 141 ILE   A CG1 1 
ATOM   780  C  CG2 . ILE   A 1 141 ? 108.907 106.210 94.583  1.00 59.67  ? 141 ILE   A CG2 1 
ATOM   781  C  CD1 . ILE   A 1 141 ? 106.285 104.660 94.910  1.00 59.67  ? 141 ILE   A CD1 1 
ATOM   782  N  N   . LEU   A 1 142 ? 105.656 107.546 91.620  1.00 62.23  ? 142 LEU   A N   1 
ATOM   783  C  CA  . LEU   A 1 142 ? 104.688 107.579 90.528  1.00 62.23  ? 142 LEU   A CA  1 
ATOM   784  C  C   . LEU   A 1 142 ? 105.072 108.621 89.488  1.00 62.23  ? 142 LEU   A C   1 
ATOM   785  O  O   . LEU   A 1 142 ? 104.834 108.433 88.290  1.00 62.23  ? 142 LEU   A O   1 
ATOM   786  C  CB  . LEU   A 1 142 ? 103.290 107.867 91.074  1.00 62.23  ? 142 LEU   A CB  1 
ATOM   787  C  CG  . LEU   A 1 142 ? 102.484 106.686 91.610  1.00 62.23  ? 142 LEU   A CG  1 
ATOM   788  C  CD1 . LEU   A 1 142 ? 101.227 107.189 92.293  1.00 62.23  ? 142 LEU   A CD1 1 
ATOM   789  C  CD2 . LEU   A 1 142 ? 102.143 105.723 90.488  1.00 62.23  ? 142 LEU   A CD2 1 
ATOM   790  N  N   . ALA   A 1 143 ? 105.646 109.739 89.933  1.00 57.40  ? 143 ALA   A N   1 
ATOM   791  C  CA  . ALA   A 1 143 ? 106.066 110.782 89.003  1.00 57.40  ? 143 ALA   A CA  1 
ATOM   792  C  C   . ALA   A 1 143 ? 107.113 110.259 88.028  1.00 57.40  ? 143 ALA   A C   1 
ATOM   793  O  O   . ALA   A 1 143 ? 106.966 110.393 86.806  1.00 57.40  ? 143 ALA   A O   1 
ATOM   794  C  CB  . ALA   A 1 143 ? 106.602 111.987 89.774  1.00 57.40  ? 143 ALA   A CB  1 
ATOM   795  N  N   . TRP   A 1 144 ? 108.174 109.638 88.539  1.00 60.37  ? 144 TRP   A N   1 
ATOM   796  C  CA  . TRP   A 1 144 ? 109.129 109.121 87.563  1.00 60.37  ? 144 TRP   A CA  1 
ATOM   797  C  C   . TRP   A 1 144 ? 108.651 107.837 86.889  1.00 60.37  ? 144 TRP   A C   1 
ATOM   798  O  O   . TRP   A 1 144 ? 109.148 107.509 85.807  1.00 60.37  ? 144 TRP   A O   1 
ATOM   799  C  CB  . TRP   A 1 144 ? 110.537 108.932 88.151  1.00 60.37  ? 144 TRP   A CB  1 
ATOM   800  C  CG  . TRP   A 1 144 ? 110.723 107.985 89.292  1.00 60.37  ? 144 TRP   A CG  1 
ATOM   801  C  CD1 . TRP   A 1 144 ? 110.592 106.629 89.264  1.00 60.37  ? 144 TRP   A CD1 1 
ATOM   802  C  CD2 . TRP   A 1 144 ? 111.220 108.310 90.598  1.00 60.37  ? 144 TRP   A CD2 1 
ATOM   803  N  NE1 . TRP   A 1 144 ? 110.905 106.097 90.492  1.00 60.37  ? 144 TRP   A NE1 1 
ATOM   804  C  CE2 . TRP   A 1 144 ? 111.300 107.108 91.327  1.00 60.37  ? 144 TRP   A CE2 1 
ATOM   805  C  CE3 . TRP   A 1 144 ? 111.576 109.506 91.231  1.00 60.37  ? 144 TRP   A CE3 1 
ATOM   806  C  CZ2 . TRP   A 1 144 ? 111.720 107.065 92.653  1.00 60.37  ? 144 TRP   A CZ2 1 
ATOM   807  C  CZ3 . TRP   A 1 144 ? 111.993 109.461 92.549  1.00 60.37  ? 144 TRP   A CZ3 1 
ATOM   808  C  CH2 . TRP   A 1 144 ? 112.059 108.250 93.246  1.00 60.37  ? 144 TRP   A CH2 1 
ATOM   809  N  N   . ALA   A 1 145 ? 107.656 107.144 87.448  1.00 61.91  ? 145 ALA   A N   1 
ATOM   810  C  CA  . ALA   A 1 145 ? 107.031 106.043 86.721  1.00 61.91  ? 145 ALA   A CA  1 
ATOM   811  C  C   . ALA   A 1 145 ? 106.305 106.548 85.478  1.00 61.91  ? 145 ALA   A C   1 
ATOM   812  O  O   . ALA   A 1 145 ? 106.420 105.964 84.394  1.00 61.91  ? 145 ALA   A O   1 
ATOM   813  C  CB  . ALA   A 1 145 ? 106.070 105.289 87.640  1.00 61.91  ? 145 ALA   A CB  1 
ATOM   814  N  N   . THR   A 1 146 ? 105.554 107.644 85.613  1.00 61.30  ? 146 THR   A N   1 
ATOM   815  C  CA  . THR   A 1 146 ? 104.879 108.204 84.446  1.00 61.30  ? 146 THR   A CA  1 
ATOM   816  C  C   . THR   A 1 146 ? 105.870 108.882 83.508  1.00 61.30  ? 146 THR   A C   1 
ATOM   817  O  O   . THR   A 1 146 ? 105.623 108.956 82.300  1.00 61.30  ? 146 THR   A O   1 
ATOM   818  C  CB  . THR   A 1 146 ? 103.770 109.175 84.865  1.00 61.30  ? 146 THR   A CB  1 
ATOM   819  O  OG1 . THR   A 1 146 ? 102.866 109.363 83.771  1.00 61.30  ? 146 THR   A OG1 1 
ATOM   820  C  CG2 . THR   A 1 146 ? 104.331 110.525 85.253  1.00 61.30  ? 146 THR   A CG2 1 
ATOM   821  N  N   . TYR   A 1 147 ? 107.001 109.359 84.034  1.00 55.17  ? 147 TYR   A N   1 
ATOM   822  C  CA  . TYR   A 1 147 ? 108.075 109.805 83.150  1.00 55.17  ? 147 TYR   A CA  1 
ATOM   823  C  C   . TYR   A 1 147 ? 108.589 108.649 82.298  1.00 55.17  ? 147 TYR   A C   1 
ATOM   824  O  O   . TYR   A 1 147 ? 108.787 108.802 81.086  1.00 55.17  ? 147 TYR   A O   1 
ATOM   825  C  CB  . TYR   A 1 147 ? 109.207 110.426 83.970  1.00 55.17  ? 147 TYR   A CB  1 
ATOM   826  C  CG  . TYR   A 1 147 ? 110.346 110.983 83.143  1.00 55.17  ? 147 TYR   A CG  1 
ATOM   827  C  CD1 . TYR   A 1 147 ? 111.376 110.165 82.699  1.00 55.17  ? 147 TYR   A CD1 1 
ATOM   828  C  CD2 . TYR   A 1 147 ? 110.391 112.328 82.809  1.00 55.17  ? 147 TYR   A CD2 1 
ATOM   829  C  CE1 . TYR   A 1 147 ? 112.414 110.670 81.945  1.00 55.17  ? 147 TYR   A CE1 1 
ATOM   830  C  CE2 . TYR   A 1 147 ? 111.427 112.841 82.056  1.00 55.17  ? 147 TYR   A CE2 1 
ATOM   831  C  CZ  . TYR   A 1 147 ? 112.435 112.006 81.627  1.00 55.17  ? 147 TYR   A CZ  1 
ATOM   832  O  OH  . TYR   A 1 147 ? 113.471 112.509 80.876  1.00 55.17  ? 147 TYR   A OH  1 
ATOM   833  N  N   . TYR   A 1 148 ? 108.796 107.482 82.915  1.00 65.67  ? 148 TYR   A N   1 
ATOM   834  C  CA  . TYR   A 1 148 ? 109.168 106.289 82.159  1.00 65.67  ? 148 TYR   A CA  1 
ATOM   835  C  C   . TYR   A 1 148 ? 108.105 105.935 81.126  1.00 65.67  ? 148 TYR   A C   1 
ATOM   836  O  O   . TYR   A 1 148 ? 108.425 105.578 79.985  1.00 65.67  ? 148 TYR   A O   1 
ATOM   837  C  CB  . TYR   A 1 148 ? 109.383 105.112 83.110  1.00 65.67  ? 148 TYR   A CB  1 
ATOM   838  C  CG  . TYR   A 1 148 ? 110.813 104.890 83.544  1.00 65.67  ? 148 TYR   A CG  1 
ATOM   839  C  CD1 . TYR   A 1 148 ? 111.634 104.011 82.855  1.00 65.67  ? 148 TYR   A CD1 1 
ATOM   840  C  CD2 . TYR   A 1 148 ? 111.331 105.533 84.659  1.00 65.67  ? 148 TYR   A CD2 1 
ATOM   841  C  CE1 . TYR   A 1 148 ? 112.937 103.794 83.247  1.00 65.67  ? 148 TYR   A CE1 1 
ATOM   842  C  CE2 . TYR   A 1 148 ? 112.635 105.320 85.060  1.00 65.67  ? 148 TYR   A CE2 1 
ATOM   843  C  CZ  . TYR   A 1 148 ? 113.432 104.449 84.349  1.00 65.67  ? 148 TYR   A CZ  1 
ATOM   844  O  OH  . TYR   A 1 148 ? 114.732 104.228 84.739  1.00 65.67  ? 148 TYR   A OH  1 
ATOM   845  N  N   . LEU   A 1 149 ? 106.832 106.016 81.517  1.00 65.62  ? 149 LEU   A N   1 
ATOM   846  C  CA  . LEU   A 1 149 ? 105.741 105.714 80.594  1.00 65.62  ? 149 LEU   A CA  1 
ATOM   847  C  C   . LEU   A 1 149 ? 105.782 106.623 79.373  1.00 65.62  ? 149 LEU   A C   1 
ATOM   848  O  O   . LEU   A 1 149 ? 105.703 106.152 78.232  1.00 65.62  ? 149 LEU   A O   1 
ATOM   849  C  CB  . LEU   A 1 149 ? 104.397 105.845 81.313  1.00 65.62  ? 149 LEU   A CB  1 
ATOM   850  C  CG  . LEU   A 1 149 ? 103.144 105.694 80.448  1.00 65.62  ? 149 LEU   A CG  1 
ATOM   851  C  CD1 . LEU   A 1 149 ? 103.046 104.294 79.870  1.00 65.62  ? 149 LEU   A CD1 1 
ATOM   852  C  CD2 . LEU   A 1 149 ? 101.896 106.039 81.244  1.00 65.62  ? 149 LEU   A CD2 1 
ATOM   853  N  N   . PHE   A 1 150 ? 105.913 107.934 79.593  1.00 64.31  ? 150 PHE   A N   1 
ATOM   854  C  CA  . PHE   A 1 150 ? 105.954 108.870 78.475  1.00 64.31  ? 150 PHE   A CA  1 
ATOM   855  C  C   . PHE   A 1 150 ? 107.204 108.681 77.629  1.00 64.31  ? 150 PHE   A C   1 
ATOM   856  O  O   . PHE   A 1 150 ? 107.167 108.896 76.413  1.00 64.31  ? 150 PHE   A O   1 
ATOM   857  C  CB  . PHE   A 1 150 ? 105.870 110.308 78.983  1.00 64.31  ? 150 PHE   A CB  1 
ATOM   858  C  CG  . PHE   A 1 150 ? 104.468 110.775 79.251  1.00 64.31  ? 150 PHE   A CG  1 
ATOM   859  C  CD1 . PHE   A 1 150 ? 103.386 109.961 78.963  1.00 64.31  ? 150 PHE   A CD1 1 
ATOM   860  C  CD2 . PHE   A 1 150 ? 104.233 112.029 79.787  1.00 64.31  ? 150 PHE   A CD2 1 
ATOM   861  C  CE1 . PHE   A 1 150 ? 102.097 110.388 79.207  1.00 64.31  ? 150 PHE   A CE1 1 
ATOM   862  C  CE2 . PHE   A 1 150 ? 102.945 112.461 80.033  1.00 64.31  ? 150 PHE   A CE2 1 
ATOM   863  C  CZ  . PHE   A 1 150 ? 101.876 111.639 79.743  1.00 64.31  ? 150 PHE   A CZ  1 
ATOM   864  N  N   . GLN   A 1 151 ? 108.316 108.280 78.245  1.00 66.47  ? 151 GLN   A N   1 
ATOM   865  C  CA  . GLN   A 1 151 ? 109.550 108.030 77.516  1.00 66.47  ? 151 GLN   A CA  1 
ATOM   866  C  C   . GLN   A 1 151 ? 109.552 106.672 76.821  1.00 66.47  ? 151 GLN   A C   1 
ATOM   867  O  O   . GLN   A 1 151 ? 110.469 106.383 76.043  1.00 66.47  ? 151 GLN   A O   1 
ATOM   868  C  CB  . GLN   A 1 151 ? 110.747 108.146 78.463  1.00 66.47  ? 151 GLN   A CB  1 
ATOM   869  C  CG  . GLN   A 1 151 ? 112.067 108.465 77.780  1.00 66.47  ? 151 GLN   A CG  1 
ATOM   870  C  CD  . GLN   A 1 151 ? 112.365 109.950 77.752  1.00 66.47  ? 151 GLN   A CD  1 
ATOM   871  O  OE1 . GLN   A 1 151 ? 111.805 110.723 78.528  1.00 66.47  ? 151 GLN   A OE1 1 
ATOM   872  N  NE2 . GLN   A 1 151 ? 113.254 110.357 76.854  1.00 66.47  ? 151 GLN   A NE2 1 
ATOM   873  N  N   . SER   A 1 152 ? 108.546 105.835 77.080  1.00 70.10  ? 152 SER   A N   1 
ATOM   874  C  CA  . SER   A 1 152 ? 108.461 104.518 76.462  1.00 70.10  ? 152 SER   A CA  1 
ATOM   875  C  C   . SER   A 1 152 ? 107.742 104.511 75.119  1.00 70.10  ? 152 SER   A C   1 
ATOM   876  O  O   . SER   A 1 152 ? 107.732 103.472 74.450  1.00 70.10  ? 152 SER   A O   1 
ATOM   877  C  CB  . SER   A 1 152 ? 107.756 103.537 77.405  1.00 70.10  ? 152 SER   A CB  1 
ATOM   878  O  OG  . SER   A 1 152 ? 106.365 103.800 77.461  1.00 70.10  ? 152 SER   A OG  1 
ATOM   879  N  N   . PHE   A 1 153 ? 107.143 105.632 74.705  1.00 71.39  ? 153 PHE   A N   1 
ATOM   880  C  CA  . PHE   A 1 153 ? 106.395 105.648 73.450  1.00 71.39  ? 153 PHE   A CA  1 
ATOM   881  C  C   . PHE   A 1 153 ? 107.312 105.628 72.234  1.00 71.39  ? 153 PHE   A C   1 
ATOM   882  O  O   . PHE   A 1 153 ? 106.843 105.411 71.111  1.00 71.39  ? 153 PHE   A O   1 
ATOM   883  C  CB  . PHE   A 1 153 ? 105.479 106.873 73.391  1.00 71.39  ? 153 PHE   A CB  1 
ATOM   884  C  CG  . PHE   A 1 153 ? 104.185 106.705 74.139  1.00 71.39  ? 153 PHE   A CG  1 
ATOM   885  C  CD1 . PHE   A 1 153 ? 103.914 105.542 74.837  1.00 71.39  ? 153 PHE   A CD1 1 
ATOM   886  C  CD2 . PHE   A 1 153 ? 103.235 107.713 74.135  1.00 71.39  ? 153 PHE   A CD2 1 
ATOM   887  C  CE1 . PHE   A 1 153 ? 102.722 105.390 75.522  1.00 71.39  ? 153 PHE   A CE1 1 
ATOM   888  C  CE2 . PHE   A 1 153 ? 102.042 107.566 74.817  1.00 71.39  ? 153 PHE   A CE2 1 
ATOM   889  C  CZ  . PHE   A 1 153 ? 101.786 106.403 75.511  1.00 71.39  ? 153 PHE   A CZ  1 
ATOM   890  N  N   . GLN   A 1 154 ? 108.611 105.852 72.427  1.00 75.92  ? 154 GLN   A N   1 
ATOM   891  C  CA  . GLN   A 1 154 ? 109.529 105.931 71.299  1.00 75.92  ? 154 GLN   A CA  1 
ATOM   892  C  C   . GLN   A 1 154 ? 109.652 104.582 70.605  1.00 75.92  ? 154 GLN   A C   1 
ATOM   893  O  O   . GLN   A 1 154 ? 109.338 103.532 71.174  1.00 75.92  ? 154 GLN   A O   1 
ATOM   894  C  CB  . GLN   A 1 154 ? 110.907 106.407 71.761  1.00 75.92  ? 154 GLN   A CB  1 
ATOM   895  C  CG  . GLN   A 1 154 ? 110.886 107.707 72.539  1.00 75.92  ? 154 GLN   A CG  1 
ATOM   896  C  CD  . GLN   A 1 154 ? 112.132 107.896 73.376  1.00 75.92  ? 154 GLN   A CD  1 
ATOM   897  O  OE1 . GLN   A 1 154 ? 113.163 108.349 72.881  1.00 75.92  ? 154 GLN   A OE1 1 
ATOM   898  N  NE2 . GLN   A 1 154 ? 112.046 107.541 74.651  1.00 75.92  ? 154 GLN   A NE2 1 
ATOM   899  N  N   . LYS   A 1 155 ? 110.106 104.622 69.350  1.00 86.70  ? 155 LYS   A N   1 
ATOM   900  C  CA  . LYS   A 1 155 ? 110.267 103.397 68.572  1.00 86.70  ? 155 LYS   A CA  1 
ATOM   901  C  C   . LYS   A 1 155 ? 111.313 102.483 69.199  1.00 86.70  ? 155 LYS   A C   1 
ATOM   902  O  O   . LYS   A 1 155 ? 111.123 101.264 69.278  1.00 86.70  ? 155 LYS   A O   1 
ATOM   903  C  CB  . LYS   A 1 155 ? 110.639 103.744 67.129  1.00 86.70  ? 155 LYS   A CB  1 
ATOM   904  C  CG  . LYS   A 1 155 ? 110.624 102.565 66.163  1.00 86.70  ? 155 LYS   A CG  1 
ATOM   905  C  CD  . LYS   A 1 155 ? 112.008 101.956 65.987  1.00 86.70  ? 155 LYS   A CD  1 
ATOM   906  C  CE  . LYS   A 1 155 ? 111.988 100.829 64.968  1.00 86.70  ? 155 LYS   A CE  1 
ATOM   907  N  NZ  . LYS   A 1 155 ? 113.326 100.195 64.816  1.00 86.70  ? 155 LYS   A NZ  1 
ATOM   908  N  N   . GLU   A 1 156 ? 112.425 103.054 69.650  1.00 84.37  ? 156 GLU   A N   1 
ATOM   909  C  CA  . GLU   A 1 156 ? 113.503 102.301 70.274  1.00 84.37  ? 156 GLU   A CA  1 
ATOM   910  C  C   . GLU   A 1 156 ? 113.612 102.680 71.744  1.00 84.37  ? 156 GLU   A C   1 
ATOM   911  O  O   . GLU   A 1 156 ? 113.521 103.859 72.099  1.00 84.37  ? 156 GLU   A O   1 
ATOM   912  C  CB  . GLU   A 1 156 ? 114.837 102.556 69.568  1.00 84.37  ? 156 GLU   A CB  1 
ATOM   913  C  CG  . GLU   A 1 156 ? 115.778 101.361 69.566  1.00 84.37  ? 156 GLU   A CG  1 
ATOM   914  C  CD  . GLU   A 1 156 ? 115.423 100.334 68.507  1.00 84.37  ? 156 GLU   A CD  1 
ATOM   915  O  OE1 . GLU   A 1 156 ? 114.461 100.565 67.746  1.00 84.37  ? 156 GLU   A OE1 1 
ATOM   916  O  OE2 . GLU   A 1 156 ? 116.110 99.293  68.435  1.00 84.37  ? 156 GLU   A OE2 1 
ATOM   917  N  N   . LEU   A 1 157 ? 113.801 101.676 72.591  1.00 76.12  ? 157 LEU   A N   1 
ATOM   918  C  CA  . LEU   A 1 157 ? 113.884 101.917 74.023  1.00 76.12  ? 157 LEU   A CA  1 
ATOM   919  C  C   . LEU   A 1 157 ? 115.152 102.702 74.350  1.00 76.12  ? 157 LEU   A C   1 
ATOM   920  O  O   . LEU   A 1 157 ? 116.246 102.311 73.919  1.00 76.12  ? 157 LEU   A O   1 
ATOM   921  C  CB  . LEU   A 1 157 ? 113.866 100.594 74.786  1.00 76.12  ? 157 LEU   A CB  1 
ATOM   922  C  CG  . LEU   A 1 157 ? 112.485 99.965  74.977  1.00 76.12  ? 157 LEU   A CG  1 
ATOM   923  C  CD1 . LEU   A 1 157 ? 112.537 98.861  76.017  1.00 76.12  ? 157 LEU   A CD1 1 
ATOM   924  C  CD2 . LEU   A 1 157 ? 111.460 101.020 75.364  1.00 76.12  ? 157 LEU   A CD2 1 
ATOM   925  N  N   . PRO   A 1 158 ? 115.050 103.810 75.088  1.00 73.98  ? 158 PRO   A N   1 
ATOM   926  C  CA  . PRO   A 1 158 ? 116.253 104.603 75.391  1.00 73.98  ? 158 PRO   A CA  1 
ATOM   927  C  C   . PRO   A 1 158 ? 117.295 103.858 76.207  1.00 73.98  ? 158 PRO   A C   1 
ATOM   928  O  O   . PRO   A 1 158 ? 118.493 104.127 76.054  1.00 73.98  ? 158 PRO   A O   1 
ATOM   929  C  CB  . PRO   A 1 158 ? 115.691 105.807 76.161  1.00 73.98  ? 158 PRO   A CB  1 
ATOM   930  C  CG  . PRO   A 1 158 ? 114.378 105.344 76.695  1.00 73.98  ? 158 PRO   A CG  1 
ATOM   931  C  CD  . PRO   A 1 158 ? 113.834 104.393 75.678  1.00 73.98  ? 158 PRO   A CD  1 
ATOM   932  N  N   . TRP   A 1 159 ? 116.882 102.930 77.066  1.00 74.01  ? 159 TRP   A N   1 
ATOM   933  C  CA  . TRP   A 1 159 ? 117.796 102.249 77.973  1.00 74.01  ? 159 TRP   A CA  1 
ATOM   934  C  C   . TRP   A 1 159 ? 118.381 100.972 77.384  1.00 74.01  ? 159 TRP   A C   1 
ATOM   935  O  O   . TRP   A 1 159 ? 119.098 100.253 78.087  1.00 74.01  ? 159 TRP   A O   1 
ATOM   936  C  CB  . TRP   A 1 159 ? 117.088 101.935 79.294  1.00 74.01  ? 159 TRP   A CB  1 
ATOM   937  C  CG  . TRP   A 1 159 ? 115.833 101.137 79.138  1.00 74.01  ? 159 TRP   A CG  1 
ATOM   938  C  CD1 . TRP   A 1 159 ? 115.735 99.823  78.788  1.00 74.01  ? 159 TRP   A CD1 1 
ATOM   939  C  CD2 . TRP   A 1 159 ? 114.492 101.602 79.328  1.00 74.01  ? 159 TRP   A CD2 1 
ATOM   940  N  NE1 . TRP   A 1 159 ? 114.417 99.441  78.749  1.00 74.01  ? 159 TRP   A NE1 1 
ATOM   941  C  CE2 . TRP   A 1 159 ? 113.634 100.516 79.076  1.00 74.01  ? 159 TRP   A CE2 1 
ATOM   942  C  CE3 . TRP   A 1 159 ? 113.934 102.832 79.686  1.00 74.01  ? 159 TRP   A CE3 1 
ATOM   943  C  CZ2 . TRP   A 1 159 ? 112.249 100.622 79.171  1.00 74.01  ? 159 TRP   A CZ2 1 
ATOM   944  C  CZ3 . TRP   A 1 159 ? 112.559 102.935 79.778  1.00 74.01  ? 159 TRP   A CZ3 1 
ATOM   945  C  CH2 . TRP   A 1 159 ? 111.733 101.838 79.523  1.00 74.01  ? 159 TRP   A CH2 1 
ATOM   946  N  N   . ALA   A 1 160 ? 118.094 100.672 76.121  1.00 90.09  ? 160 ALA   A N   1 
ATOM   947  C  CA  . ALA   A 1 160 ? 118.629 99.490  75.464  1.00 90.09  ? 160 ALA   A CA  1 
ATOM   948  C  C   . ALA   A 1 160 ? 119.887 99.778  74.659  1.00 90.09  ? 160 ALA   A C   1 
ATOM   949  O  O   . ALA   A 1 160 ? 120.460 98.850  74.078  1.00 90.09  ? 160 ALA   A O   1 
ATOM   950  C  CB  . ALA   A 1 160 ? 117.568 98.863  74.553  1.00 90.09  ? 160 ALA   A CB  1 
ATOM   951  N  N   . HIS   A 1 161 ? 120.332 101.028 74.609  1.00 95.88  ? 161 HIS   A N   1 
ATOM   952  C  CA  . HIS   A 1 161 ? 121.515 101.411 73.857  1.00 95.88  ? 161 HIS   A CA  1 
ATOM   953  C  C   . HIS   A 1 161 ? 122.479 102.192 74.741  1.00 95.88  ? 161 HIS   A C   1 
ATOM   954  O  O   . HIS   A 1 161 ? 122.122 102.677 75.818  1.00 95.88  ? 161 HIS   A O   1 
ATOM   955  C  CB  . HIS   A 1 161 ? 121.136 102.236 72.623  1.00 95.88  ? 161 HIS   A CB  1 
ATOM   956  C  CG  . HIS   A 1 161 ? 120.453 101.439 71.556  1.00 95.88  ? 161 HIS   A CG  1 
ATOM   957  N  ND1 . HIS   A 1 161 ? 121.130 100.563 70.735  1.00 95.88  ? 161 HIS   A ND1 1 
ATOM   958  C  CD2 . HIS   A 1 161 ? 119.154 101.380 71.181  1.00 95.88  ? 161 HIS   A CD2 1 
ATOM   959  C  CE1 . HIS   A 1 161 ? 120.277 100.001 69.897  1.00 95.88  ? 161 HIS   A CE1 1 
ATOM   960  N  NE2 . HIS   A 1 161 ? 119.072 100.479 70.146  1.00 95.88  ? 161 HIS   A NE2 1 
ATOM   961  N  N   . CYS   A 1 162 ? 123.718 102.309 74.264  1.00 102.56 ? 162 CYS   A N   1 
ATOM   962  C  CA  . CYS   A 1 162 ? 124.799 102.891 75.047  1.00 102.56 ? 162 CYS   A CA  1 
ATOM   963  C  C   . CYS   A 1 162 ? 125.092 104.347 74.707  1.00 102.56 ? 162 CYS   A C   1 
ATOM   964  O  O   . CYS   A 1 162 ? 125.512 105.098 75.595  1.00 102.56 ? 162 CYS   A O   1 
ATOM   965  C  CB  . CYS   A 1 162 ? 126.077 102.062 74.866  1.00 102.56 ? 162 CYS   A CB  1 
ATOM   966  S  SG  . CYS   A 1 162 ? 127.565 102.760 75.614  1.00 102.56 ? 162 CYS   A SG  1 
ATOM   967  N  N   . ASN   A 1 163 ? 124.874 104.772 73.464  1.00 101.75 ? 163 ASN   A N   1 
ATOM   968  C  CA  . ASN   A 1 163 ? 125.243 106.113 73.021  1.00 101.75 ? 163 ASN   A CA  1 
ATOM   969  C  C   . ASN   A 1 163 ? 124.101 107.079 73.316  1.00 101.75 ? 163 ASN   A C   1 
ATOM   970  O  O   . ASN   A 1 163 ? 123.047 107.024 72.674  1.00 101.75 ? 163 ASN   A O   1 
ATOM   971  C  CB  . ASN   A 1 163 ? 125.591 106.123 71.534  1.00 101.75 ? 163 ASN   A CB  1 
ATOM   972  C  CG  . ASN   A 1 163 ? 127.080 105.987 71.285  1.00 101.75 ? 163 ASN   A CG  1 
ATOM   973  O  OD1 . ASN   A 1 163 ? 127.848 105.705 72.205  1.00 101.75 ? 163 ASN   A OD1 1 
ATOM   974  N  ND2 . ASN   A 1 163 ? 127.500 106.198 70.041  1.00 101.75 ? 163 ASN   A ND2 1 
ATOM   975  N  N   . HIS   A 1 164 ? 124.322 107.968 74.281  1.00 89.09  ? 164 HIS   A N   1 
ATOM   976  C  CA  . HIS   A 1 164 ? 123.381 109.030 74.607  1.00 89.09  ? 164 HIS   A CA  1 
ATOM   977  C  C   . HIS   A 1 164 ? 124.162 110.210 75.165  1.00 89.09  ? 164 HIS   A C   1 
ATOM   978  O  O   . HIS   A 1 164 ? 125.350 110.104 75.482  1.00 89.09  ? 164 HIS   A O   1 
ATOM   979  C  CB  . HIS   A 1 164 ? 122.315 108.565 75.608  1.00 89.09  ? 164 HIS   A CB  1 
ATOM   980  C  CG  . HIS   A 1 164 ? 121.336 107.586 75.041  1.00 89.09  ? 164 HIS   A CG  1 
ATOM   981  N  ND1 . HIS   A 1 164 ? 120.358 107.949 74.141  1.00 89.09  ? 164 HIS   A ND1 1 
ATOM   982  C  CD2 . HIS   A 1 164 ? 121.183 106.256 75.246  1.00 89.09  ? 164 HIS   A CD2 1 
ATOM   983  C  CE1 . HIS   A 1 164 ? 119.645 106.886 73.816  1.00 89.09  ? 164 HIS   A CE1 1 
ATOM   984  N  NE2 . HIS   A 1 164 ? 120.126 105.846 74.473  1.00 89.09  ? 164 HIS   A NE2 1 
ATOM   985  N  N   . SER   A 1 165 ? 123.477 111.348 75.282  1.00 84.80  ? 165 SER   A N   1 
ATOM   986  C  CA  . SER   A 1 165 ? 124.098 112.547 75.831  1.00 84.80  ? 165 SER   A CA  1 
ATOM   987  C  C   . SER   A 1 165 ? 124.342 112.454 77.331  1.00 84.80  ? 165 SER   A C   1 
ATOM   988  O  O   . SER   A 1 165 ? 125.024 113.324 77.883  1.00 84.80  ? 165 SER   A O   1 
ATOM   989  C  CB  . SER   A 1 165 ? 123.234 113.771 75.524  1.00 84.80  ? 165 SER   A CB  1 
ATOM   990  O  OG  . SER   A 1 165 ? 121.865 113.506 75.775  1.00 84.80  ? 165 SER   A OG  1 
ATOM   991  N  N   . TRP   A 1 166 ? 123.804 111.435 78.002  1.00 81.32  ? 166 TRP   A N   1 
ATOM   992  C  CA  . TRP   A 1 166 ? 123.970 111.257 79.439  1.00 81.32  ? 166 TRP   A CA  1 
ATOM   993  C  C   . TRP   A 1 166 ? 124.707 109.963 79.778  1.00 81.32  ? 166 TRP   A C   1 
ATOM   994  O  O   . TRP   A 1 166 ? 124.458 109.357 80.822  1.00 81.32  ? 166 TRP   A O   1 
ATOM   995  C  CB  . TRP   A 1 166 ? 122.614 111.290 80.143  1.00 81.32  ? 166 TRP   A CB  1 
ATOM   996  C  CG  . TRP   A 1 166 ? 121.675 110.217 79.684  1.00 81.32  ? 166 TRP   A CG  1 
ATOM   997  C  CD1 . TRP   A 1 166 ? 121.444 109.018 80.291  1.00 81.32  ? 166 TRP   A CD1 1 
ATOM   998  C  CD2 . TRP   A 1 166 ? 120.824 110.254 78.532  1.00 81.32  ? 166 TRP   A CD2 1 
ATOM   999  N  NE1 . TRP   A 1 166 ? 120.513 108.300 79.582  1.00 81.32  ? 166 TRP   A NE1 1 
ATOM   1000 C  CE2 . TRP   A 1 166 ? 120.114 109.038 78.498  1.00 81.32  ? 166 TRP   A CE2 1 
ATOM   1001 C  CE3 . TRP   A 1 166 ? 120.597 111.195 77.523  1.00 81.32  ? 166 TRP   A CE3 1 
ATOM   1002 C  CZ2 . TRP   A 1 166 ? 119.194 108.738 77.496  1.00 81.32  ? 166 TRP   A CZ2 1 
ATOM   1003 C  CZ3 . TRP   A 1 166 ? 119.683 110.895 76.529  1.00 81.32  ? 166 TRP   A CZ3 1 
ATOM   1004 C  CH2 . TRP   A 1 166 ? 118.993 109.678 76.523  1.00 81.32  ? 166 TRP   A CH2 1 
ATOM   1005 N  N   . ASN   A 1 167 ? 125.616 109.529 78.908  1.00 91.99  ? 167 ASN   A N   1 
ATOM   1006 C  CA  . ASN   A 1 167 ? 126.363 108.293 79.101  1.00 91.99  ? 167 ASN   A CA  1 
ATOM   1007 C  C   . ASN   A 1 167 ? 127.854 108.591 79.128  1.00 91.99  ? 167 ASN   A C   1 
ATOM   1008 O  O   . ASN   A 1 167 ? 128.359 109.339 78.284  1.00 91.99  ? 167 ASN   A O   1 
ATOM   1009 C  CB  . ASN   A 1 167 ? 126.050 107.278 77.997  1.00 91.99  ? 167 ASN   A CB  1 
ATOM   1010 C  CG  . ASN   A 1 167 ? 124.619 106.778 78.050  1.00 91.99  ? 167 ASN   A CG  1 
ATOM   1011 O  OD1 . ASN   A 1 167 ? 123.695 107.528 78.363  1.00 91.99  ? 167 ASN   A OD1 1 
ATOM   1012 N  ND2 . ASN   A 1 167 ? 124.429 105.501 77.740  1.00 91.99  ? 167 ASN   A ND2 1 
ATOM   1013 N  N   . THR   A 1 168 ? 128.551 108.006 80.097  1.00 102.02 ? 168 THR   A N   1 
ATOM   1014 C  CA  . THR   A 1 168 ? 129.993 108.107 80.258  1.00 102.02 ? 168 THR   A CA  1 
ATOM   1015 C  C   . THR   A 1 168 ? 130.713 107.203 79.267  1.00 102.02 ? 168 THR   A C   1 
ATOM   1016 O  O   . THR   A 1 168 ? 130.110 106.298 78.682  1.00 102.02 ? 168 THR   A O   1 
ATOM   1017 C  CB  . THR   A 1 168 ? 130.389 107.724 81.683  1.00 102.02 ? 168 THR   A CB  1 
ATOM   1018 O  OG1 . THR   A 1 168 ? 130.008 106.366 81.939  1.00 102.02 ? 168 THR   A OG1 1 
ATOM   1019 C  CG2 . THR   A 1 168 ? 129.717 108.635 82.686  1.00 102.02 ? 168 THR   A CG2 1 
ATOM   1020 N  N   . PRO   A 1 169 ? 132.014 107.433 79.042  1.00 108.00 ? 169 PRO   A N   1 
ATOM   1021 C  CA  . PRO   A 1 169 ? 132.802 106.474 78.255  1.00 108.00 ? 169 PRO   A CA  1 
ATOM   1022 C  C   . PRO   A 1 169 ? 132.832 105.095 78.895  1.00 108.00 ? 169 PRO   A C   1 
ATOM   1023 O  O   . PRO   A 1 169 ? 133.048 104.089 78.211  1.00 108.00 ? 169 PRO   A O   1 
ATOM   1024 C  CB  . PRO   A 1 169 ? 134.197 107.110 78.220  1.00 108.00 ? 169 PRO   A CB  1 
ATOM   1025 C  CG  . PRO   A 1 169 ? 133.945 108.565 78.390  1.00 108.00 ? 169 PRO   A CG  1 
ATOM   1026 C  CD  . PRO   A 1 169 ? 132.769 108.668 79.318  1.00 108.00 ? 169 PRO   A CD  1 
ATOM   1027 N  N   . HIS   A 1 170 ? 132.618 105.038 80.210  1.00 112.54 ? 170 HIS   A N   1 
ATOM   1028 C  CA  . HIS   A 1 170 ? 132.534 103.772 80.938  1.00 112.54 ? 170 HIS   A CA  1 
ATOM   1029 C  C   . HIS   A 1 170 ? 131.150 103.143 80.750  1.00 112.54 ? 170 HIS   A C   1 
ATOM   1030 O  O   . HIS   A 1 170 ? 130.388 102.933 81.693  1.00 112.54 ? 170 HIS   A O   1 
ATOM   1031 C  CB  . HIS   A 1 170 ? 132.848 103.991 82.412  1.00 112.54 ? 170 HIS   A CB  1 
ATOM   1032 C  CG  . HIS   A 1 170 ? 134.306 103.906 82.740  1.00 112.54 ? 170 HIS   A CG  1 
ATOM   1033 N  ND1 . HIS   A 1 170 ? 134.856 104.511 83.850  1.00 112.54 ? 170 HIS   A ND1 1 
ATOM   1034 C  CD2 . HIS   A 1 170 ? 135.329 103.286 82.104  1.00 112.54 ? 170 HIS   A CD2 1 
ATOM   1035 C  CE1 . HIS   A 1 170 ? 136.154 104.268 83.883  1.00 112.54 ? 170 HIS   A CE1 1 
ATOM   1036 N  NE2 . HIS   A 1 170 ? 136.466 103.527 82.836  1.00 112.54 ? 170 HIS   A NE2 1 
ATOM   1037 N  N   . CYS   A 1 171 ? 130.837 102.840 79.493  1.00 109.30 ? 171 CYS   A N   1 
ATOM   1038 C  CA  . CYS   A 1 171 ? 129.535 102.309 79.094  1.00 109.30 ? 171 CYS   A CA  1 
ATOM   1039 C  C   . CYS   A 1 171 ? 129.755 101.055 78.254  1.00 109.30 ? 171 CYS   A C   1 
ATOM   1040 O  O   . CYS   A 1 171 ? 130.150 101.142 77.087  1.00 109.30 ? 171 CYS   A O   1 
ATOM   1041 C  CB  . CYS   A 1 171 ? 128.736 103.358 78.327  1.00 109.30 ? 171 CYS   A CB  1 
ATOM   1042 S  SG  . CYS   A 1 171 ? 127.192 102.755 77.610  1.00 109.30 ? 171 CYS   A SG  1 
ATOM   1043 N  N   . MET   A 1 172 ? 129.490 99.894  78.846  1.00 112.64 ? 172 MET   A N   1 
ATOM   1044 C  CA  . MET   A 1 172 ? 129.604 98.612  78.168  1.00 112.64 ? 172 MET   A CA  1 
ATOM   1045 C  C   . MET   A 1 172 ? 128.259 97.901  78.187  1.00 112.64 ? 172 MET   A C   1 
ATOM   1046 O  O   . MET   A 1 172 ? 127.549 97.925  79.197  1.00 112.64 ? 172 MET   A O   1 
ATOM   1047 C  CB  . MET   A 1 172 ? 130.669 97.729  78.829  1.00 112.64 ? 172 MET   A CB  1 
ATOM   1048 C  CG  . MET   A 1 172 ? 132.131 98.184  78.679  1.00 112.64 ? 172 MET   A CG  1 
ATOM   1049 S  SD  . MET   A 1 172 ? 132.634 99.222  77.280  1.00 112.64 ? 172 MET   A SD  1 
ATOM   1050 C  CE  . MET   A 1 172 ? 132.038 98.310  75.851  1.00 112.64 ? 172 MET   A CE  1 
ATOM   1051 N  N   . GLU   A 1 173 ? 127.910 97.274  77.066  1.00 118.16 ? 173 GLU   A N   1 
ATOM   1052 C  CA  . GLU   A 1 173 ? 126.662 96.526  76.984  1.00 118.16 ? 173 GLU   A CA  1 
ATOM   1053 C  C   . GLU   A 1 173 ? 126.732 95.291  77.874  1.00 118.16 ? 173 GLU   A C   1 
ATOM   1054 O  O   . GLU   A 1 173 ? 127.750 94.592  77.905  1.00 118.16 ? 173 GLU   A O   1 
ATOM   1055 C  CB  . GLU   A 1 173 ? 126.377 96.122  75.539  1.00 118.16 ? 173 GLU   A CB  1 
ATOM   1056 C  CG  . GLU   A 1 173 ? 125.976 97.276  74.635  1.00 118.16 ? 173 GLU   A CG  1 
ATOM   1057 C  CD  . GLU   A 1 173 ? 127.154 97.864  73.884  1.00 118.16 ? 173 GLU   A CD  1 
ATOM   1058 O  OE1 . GLU   A 1 173 ? 128.287 97.374  74.073  1.00 118.16 ? 173 GLU   A OE1 1 
ATOM   1059 O  OE2 . GLU   A 1 173 ? 126.948 98.815  73.101  1.00 118.16 ? 173 GLU   A OE2 1 
ATOM   1060 N  N   . ASP   A 1 174 ? 125.644 95.022  78.600  1.00 114.32 ? 174 ASP   A N   1 
ATOM   1061 C  CA  . ASP   A 1 174 ? 125.616 93.879  79.505  1.00 114.32 ? 174 ASP   A CA  1 
ATOM   1062 C  C   . ASP   A 1 174 ? 125.659 92.549  78.765  1.00 114.32 ? 174 ASP   A C   1 
ATOM   1063 O  O   . ASP   A 1 174 ? 126.101 91.549  79.341  1.00 114.32 ? 174 ASP   A O   1 
ATOM   1064 C  CB  . ASP   A 1 174 ? 124.376 93.944  80.397  1.00 114.32 ? 174 ASP   A CB  1 
ATOM   1065 C  CG  . ASP   A 1 174 ? 123.125 94.316  79.631  1.00 114.32 ? 174 ASP   A CG  1 
ATOM   1066 O  OD1 . ASP   A 1 174 ? 123.125 94.188  78.388  1.00 114.32 ? 174 ASP   A OD1 1 
ATOM   1067 O  OD2 . ASP   A 1 174 ? 122.144 94.748  80.271  1.00 114.32 ? 174 ASP   A OD2 1 
ATOM   1068 N  N   . THR   A 1 175 ? 125.208 92.512  77.509  1.00 119.41 ? 175 THR   A N   1 
ATOM   1069 C  CA  . THR   A 1 175 ? 125.285 91.278  76.734  1.00 119.41 ? 175 THR   A CA  1 
ATOM   1070 C  C   . THR   A 1 175 ? 126.733 90.871  76.489  1.00 119.41 ? 175 THR   A C   1 
ATOM   1071 O  O   . THR   A 1 175 ? 127.076 89.686  76.577  1.00 119.41 ? 175 THR   A O   1 
ATOM   1072 C  CB  . THR   A 1 175 ? 124.544 91.443  75.408  1.00 119.41 ? 175 THR   A CB  1 
ATOM   1073 O  OG1 . THR   A 1 175 ? 125.257 92.361  74.571  1.00 119.41 ? 175 THR   A OG1 1 
ATOM   1074 C  CG2 . THR   A 1 175 ? 123.140 91.974  75.650  1.00 119.41 ? 175 THR   A CG2 1 
ATOM   1075 N  N   . MET   A 1 176 ? 127.595 91.837  76.180  1.00 121.53 ? 176 MET   A N   1 
ATOM   1076 C  CA  . MET   A 1 176 ? 129.014 91.588  75.977  1.00 121.53 ? 176 MET   A CA  1 
ATOM   1077 C  C   . MET   A 1 176 ? 129.854 91.981  77.185  1.00 121.53 ? 176 MET   A C   1 
ATOM   1078 O  O   . MET   A 1 176 ? 131.084 92.034  77.082  1.00 121.53 ? 176 MET   A O   1 
ATOM   1079 C  CB  . MET   A 1 176 ? 129.508 92.328  74.733  1.00 121.53 ? 176 MET   A CB  1 
ATOM   1080 C  CG  . MET   A 1 176 ? 129.055 93.775  74.650  1.00 121.53 ? 176 MET   A CG  1 
ATOM   1081 S  SD  . MET   A 1 176 ? 129.321 94.494  73.019  1.00 121.53 ? 176 MET   A SD  1 
ATOM   1082 C  CE  . MET   A 1 176 ? 127.658 94.456  72.355  1.00 121.53 ? 176 MET   A CE  1 
ATOM   1083 N  N   . ARG   A 1 177 ? 129.218 92.269  78.324  1.00 117.50 ? 177 ARG   A N   1 
ATOM   1084 C  CA  . ARG   A 1 177 ? 129.969 92.636  79.521  1.00 117.50 ? 177 ARG   A CA  1 
ATOM   1085 C  C   . ARG   A 1 177 ? 130.828 91.478  80.011  1.00 117.50 ? 177 ARG   A C   1 
ATOM   1086 O  O   . ARG   A 1 177 ? 131.973 91.680  80.435  1.00 117.50 ? 177 ARG   A O   1 
ATOM   1087 C  CB  . ARG   A 1 177 ? 129.011 93.097  80.619  1.00 117.50 ? 177 ARG   A CB  1 
ATOM   1088 C  CG  . ARG   A 1 177 ? 129.684 93.832  81.764  1.00 117.50 ? 177 ARG   A CG  1 
ATOM   1089 C  CD  . ARG   A 1 177 ? 128.654 94.456  82.701  1.00 117.50 ? 177 ARG   A CD  1 
ATOM   1090 N  NE  . ARG   A 1 177 ? 129.235 94.992  83.929  1.00 117.50 ? 177 ARG   A NE  1 
ATOM   1091 C  CZ  . ARG   A 1 177 ? 129.933 94.295  84.817  1.00 117.50 ? 177 ARG   A CZ  1 
ATOM   1092 N  NH1 . ARG   A 1 177 ? 130.117 92.990  84.689  1.00 117.50 ? 177 ARG   A NH1 1 
ATOM   1093 N  NH2 . ARG   A 1 177 ? 130.444 94.920  85.874  1.00 117.50 ? 177 ARG   A NH2 1 
ATOM   1094 N  N   . LYS   A 1 178 ? 130.295 90.258  79.962  1.00 121.95 ? 178 LYS   A N   1 
ATOM   1095 C  CA  . LYS   A 1 178 ? 131.028 89.080  80.405  1.00 121.95 ? 178 LYS   A CA  1 
ATOM   1096 C  C   . LYS   A 1 178 ? 132.075 88.621  79.396  1.00 121.95 ? 178 LYS   A C   1 
ATOM   1097 O  O   . LYS   A 1 178 ? 132.867 87.727  79.712  1.00 121.95 ? 178 LYS   A O   1 
ATOM   1098 C  CB  . LYS   A 1 178 ? 130.048 87.939  80.696  1.00 121.95 ? 178 LYS   A CB  1 
ATOM   1099 C  CG  . LYS   A 1 178 ? 130.576 86.878  81.650  1.00 121.95 ? 178 LYS   A CG  1 
ATOM   1100 C  CD  . LYS   A 1 178 ? 129.521 85.824  81.944  1.00 121.95 ? 178 LYS   A CD  1 
ATOM   1101 C  CE  . LYS   A 1 178 ? 128.468 86.351  82.905  1.00 121.95 ? 178 LYS   A CE  1 
ATOM   1102 N  NZ  . LYS   A 1 178 ? 127.533 85.281  83.350  1.00 121.95 ? 178 LYS   A NZ  1 
ATOM   1103 N  N   . ASN   A 1 179 ? 132.099 89.208  78.203  1.00 133.17 ? 179 ASN   A N   1 
ATOM   1104 C  CA  . ASN   A 1 179 ? 133.070 88.842  77.176  1.00 133.17 ? 179 ASN   A CA  1 
ATOM   1105 C  C   . ASN   A 1 179 ? 134.496 89.136  77.631  1.00 133.17 ? 179 ASN   A C   1 
ATOM   1106 O  O   . ASN   A 1 179 ? 134.748 90.129  78.314  1.00 133.17 ? 179 ASN   A O   1 
ATOM   1107 C  CB  . ASN   A 1 179 ? 132.773 89.586  75.873  1.00 133.17 ? 179 ASN   A CB  1 
ATOM   1108 C  CG  . ASN   A 1 179 ? 132.919 88.705  74.649  1.00 133.17 ? 179 ASN   A CG  1 
ATOM   1109 O  OD1 . ASN   A 1 179 ? 133.759 87.806  74.612  1.00 133.17 ? 179 ASN   A OD1 1 
ATOM   1110 N  ND2 . ASN   A 1 179 ? 132.098 88.962  73.636  1.00 133.17 ? 179 ASN   A ND2 1 
ATOM   1111 N  N   . THR   A 1 189 ? 137.027 96.103  86.735  1.00 124.01 ? 189 THR   A N   1 
ATOM   1112 C  CA  . THR   A 1 189 ? 136.157 96.523  87.827  1.00 124.01 ? 189 THR   A CA  1 
ATOM   1113 C  C   . THR   A 1 189 ? 135.828 98.007  87.723  1.00 124.01 ? 189 THR   A C   1 
ATOM   1114 O  O   . THR   A 1 189 ? 135.640 98.681  88.736  1.00 124.01 ? 189 THR   A O   1 
ATOM   1115 C  CB  . THR   A 1 189 ? 136.796 96.247  89.200  1.00 124.01 ? 189 THR   A CB  1 
ATOM   1116 O  OG1 . THR   A 1 189 ? 137.823 97.213  89.454  1.00 124.01 ? 189 THR   A OG1 1 
ATOM   1117 C  CG2 . THR   A 1 189 ? 137.400 94.851  89.236  1.00 124.01 ? 189 THR   A CG2 1 
ATOM   1118 N  N   . ASN   A 1 190 ? 135.759 98.514  86.494  1.00 122.50 ? 190 ASN   A N   1 
ATOM   1119 C  CA  . ASN   A 1 190 ? 135.490 99.927  86.255  1.00 122.50 ? 190 ASN   A CA  1 
ATOM   1120 C  C   . ASN   A 1 190 ? 134.394 100.095 85.210  1.00 122.50 ? 190 ASN   A C   1 
ATOM   1121 O  O   . ASN   A 1 190 ? 134.340 101.104 84.499  1.00 122.50 ? 190 ASN   A O   1 
ATOM   1122 C  CB  . ASN   A 1 190 ? 136.762 100.667 85.833  1.00 122.50 ? 190 ASN   A CB  1 
ATOM   1123 C  CG  . ASN   A 1 190 ? 137.420 100.064 84.590  1.00 122.50 ? 190 ASN   A CG  1 
ATOM   1124 O  OD1 . ASN   A 1 190 ? 136.728 99.589  83.691  1.00 122.50 ? 190 ASN   A OD1 1 
ATOM   1125 N  ND2 . ASN   A 1 190 ? 138.758 100.094 84.519  1.00 122.50 ? 190 ASN   A ND2 1 
ATOM   1126 N  N   . PHE   A 1 191 ? 133.504 99.111  85.103  1.00 115.54 ? 191 PHE   A N   1 
ATOM   1127 C  CA  . PHE   A 1 191 ? 132.493 99.088  84.055  1.00 115.54 ? 191 PHE   A CA  1 
ATOM   1128 C  C   . PHE   A 1 191 ? 131.105 98.984  84.668  1.00 115.54 ? 191 PHE   A C   1 
ATOM   1129 O  O   . PHE   A 1 191 ? 130.930 98.386  85.734  1.00 115.54 ? 191 PHE   A O   1 
ATOM   1130 C  CB  . PHE   A 1 191 ? 132.724 97.917  83.092  1.00 115.54 ? 191 PHE   A CB  1 
ATOM   1131 C  CG  . PHE   A 1 191 ? 133.828 98.155  82.104  1.00 115.54 ? 191 PHE   A CG  1 
ATOM   1132 C  CD1 . PHE   A 1 191 ? 134.193 99.442  81.748  1.00 115.54 ? 191 PHE   A CD1 1 
ATOM   1133 C  CD2 . PHE   A 1 191 ? 134.505 97.090  81.534  1.00 115.54 ? 191 PHE   A CD2 1 
ATOM   1134 C  CE1 . PHE   A 1 191 ? 135.211 99.664  80.840  1.00 115.54 ? 191 PHE   A CE1 1 
ATOM   1135 C  CE2 . PHE   A 1 191 ? 135.524 97.305  80.625  1.00 115.54 ? 191 PHE   A CE2 1 
ATOM   1136 C  CZ  . PHE   A 1 191 ? 135.877 98.593  80.278  1.00 115.54 ? 191 PHE   A CZ  1 
ATOM   1137 N  N   . THR   A 1 192 ? 130.123 99.572  83.989  1.00 103.30 ? 192 THR   A N   1 
ATOM   1138 C  CA  . THR   A 1 192 ? 128.728 99.517  84.400  1.00 103.30 ? 192 THR   A CA  1 
ATOM   1139 C  C   . THR   A 1 192 ? 127.868 99.112  83.210  1.00 103.30 ? 192 THR   A C   1 
ATOM   1140 O  O   . THR   A 1 192 ? 128.362 98.890  82.101  1.00 103.30 ? 192 THR   A O   1 
ATOM   1141 C  CB  . THR   A 1 192 ? 128.247 100.862 84.964  1.00 103.30 ? 192 THR   A CB  1 
ATOM   1142 O  OG1 . THR   A 1 192 ? 128.436 101.890 83.985  1.00 103.30 ? 192 THR   A OG1 1 
ATOM   1143 C  CG2 . THR   A 1 192 ? 129.012 101.219 86.230  1.00 103.30 ? 192 THR   A CG2 1 
ATOM   1144 N  N   . SER   A 1 193 ? 126.567 99.020  83.451  1.00 98.55  ? 193 SER   A N   1 
ATOM   1145 C  CA  . SER   A 1 193 ? 125.595 98.638  82.440  1.00 98.55  ? 193 SER   A CA  1 
ATOM   1146 C  C   . SER   A 1 193 ? 124.799 99.851  81.979  1.00 98.55  ? 193 SER   A C   1 
ATOM   1147 O  O   . SER   A 1 193 ? 124.637 100.821 82.726  1.00 98.55  ? 193 SER   A O   1 
ATOM   1148 C  CB  . SER   A 1 193 ? 124.636 97.571  82.986  1.00 98.55  ? 193 SER   A CB  1 
ATOM   1149 O  OG  . SER   A 1 193 ? 123.800 98.109  83.994  1.00 98.55  ? 193 SER   A OG  1 
ATOM   1150 N  N   . PRO   A 1 194 ? 124.292 99.835  80.738  1.00 90.88  ? 194 PRO   A N   1 
ATOM   1151 C  CA  . PRO   A 1 194 ? 123.570 101.003 80.213  1.00 90.88  ? 194 PRO   A CA  1 
ATOM   1152 C  C   . PRO   A 1 194 ? 122.381 101.426 81.062  1.00 90.88  ? 194 PRO   A C   1 
ATOM   1153 O  O   . PRO   A 1 194 ? 122.131 102.625 81.229  1.00 90.88  ? 194 PRO   A O   1 
ATOM   1154 C  CB  . PRO   A 1 194 ? 123.120 100.528 78.828  1.00 90.88  ? 194 PRO   A CB  1 
ATOM   1155 C  CG  . PRO   A 1 194 ? 124.167 99.546  78.431  1.00 90.88  ? 194 PRO   A CG  1 
ATOM   1156 C  CD  . PRO   A 1 194 ? 124.496 98.809  79.700  1.00 90.88  ? 194 PRO   A CD  1 
ATOM   1157 N  N   . VAL   A 1 195 ? 121.643 100.456 81.606  1.00 83.40  ? 195 VAL   A N   1 
ATOM   1158 C  CA  . VAL   A 1 195 ? 120.476 100.787 82.420  1.00 83.40  ? 195 VAL   A CA  1 
ATOM   1159 C  C   . VAL   A 1 195 ? 120.893 101.462 83.721  1.00 83.40  ? 195 VAL   A C   1 
ATOM   1160 O  O   . VAL   A 1 195 ? 120.206 102.372 84.205  1.00 83.40  ? 195 VAL   A O   1 
ATOM   1161 C  CB  . VAL   A 1 195 ? 119.621 99.528  82.668  1.00 83.40  ? 195 VAL   A CB  1 
ATOM   1162 C  CG1 . VAL   A 1 195 ? 120.416 98.463  83.410  1.00 83.40  ? 195 VAL   A CG1 1 
ATOM   1163 C  CG2 . VAL   A 1 195 ? 118.355 99.887  83.431  1.00 83.40  ? 195 VAL   A CG2 1 
ATOM   1164 N  N   . ILE   A 1 196 ? 122.020 101.043 84.303  1.00 84.50  ? 196 ILE   A N   1 
ATOM   1165 C  CA  . ILE   A 1 196 ? 122.511 101.680 85.522  1.00 84.50  ? 196 ILE   A CA  1 
ATOM   1166 C  C   . ILE   A 1 196 ? 122.848 103.142 85.261  1.00 84.50  ? 196 ILE   A C   1 
ATOM   1167 O  O   . ILE   A 1 196 ? 122.481 104.029 86.040  1.00 84.50  ? 196 ILE   A O   1 
ATOM   1168 C  CB  . ILE   A 1 196 ? 123.724 100.909 86.077  1.00 84.50  ? 196 ILE   A CB  1 
ATOM   1169 C  CG1 . ILE   A 1 196 ? 123.270 99.617  86.759  1.00 84.50  ? 196 ILE   A CG1 1 
ATOM   1170 C  CG2 . ILE   A 1 196 ? 124.513 101.771 87.047  1.00 84.50  ? 196 ILE   A CG2 1 
ATOM   1171 C  CD1 . ILE   A 1 196 ? 122.395 99.841  87.970  1.00 84.50  ? 196 ILE   A CD1 1 
ATOM   1172 N  N   . GLU   A 1 197 ? 123.544 103.416 84.156  1.00 83.27  ? 197 GLU   A N   1 
ATOM   1173 C  CA  . GLU   A 1 197 ? 123.871 104.794 83.807  1.00 83.27  ? 197 GLU   A CA  1 
ATOM   1174 C  C   . GLU   A 1 197 ? 122.610 105.604 83.537  1.00 83.27  ? 197 GLU   A C   1 
ATOM   1175 O  O   . GLU   A 1 197 ? 122.501 106.762 83.958  1.00 83.27  ? 197 GLU   A O   1 
ATOM   1176 C  CB  . GLU   A 1 197 ? 124.797 104.820 82.592  1.00 83.27  ? 197 GLU   A CB  1 
ATOM   1177 C  CG  . GLU   A 1 197 ? 126.233 104.441 82.901  1.00 83.27  ? 197 GLU   A CG  1 
ATOM   1178 C  CD  . GLU   A 1 197 ? 127.020 104.090 81.656  1.00 83.27  ? 197 GLU   A CD  1 
ATOM   1179 O  OE1 . GLU   A 1 197 ? 126.524 103.281 80.844  1.00 83.27  ? 197 GLU   A OE1 1 
ATOM   1180 O  OE2 . GLU   A 1 197 ? 128.136 104.624 81.488  1.00 83.27  ? 197 GLU   A OE2 1 
ATOM   1181 N  N   . PHE   A 1 198 ? 121.651 105.013 82.821  1.00 74.10  ? 198 PHE   A N   1 
ATOM   1182 C  CA  . PHE   A 1 198 ? 120.414 105.721 82.517  1.00 74.10  ? 198 PHE   A CA  1 
ATOM   1183 C  C   . PHE   A 1 198 ? 119.674 106.111 83.788  1.00 74.10  ? 198 PHE   A C   1 
ATOM   1184 O  O   . PHE   A 1 198 ? 119.309 107.280 83.956  1.00 74.10  ? 198 PHE   A O   1 
ATOM   1185 C  CB  . PHE   A 1 198 ? 119.531 104.853 81.611  1.00 74.10  ? 198 PHE   A CB  1 
ATOM   1186 C  CG  . PHE   A 1 198 ? 118.216 105.489 81.236  1.00 74.10  ? 198 PHE   A CG  1 
ATOM   1187 C  CD1 . PHE   A 1 198 ? 118.076 106.154 80.031  1.00 74.10  ? 198 PHE   A CD1 1 
ATOM   1188 C  CD2 . PHE   A 1 198 ? 117.110 105.388 82.067  1.00 74.10  ? 198 PHE   A CD2 1 
ATOM   1189 C  CE1 . PHE   A 1 198 ? 116.871 106.731 79.676  1.00 74.10  ? 198 PHE   A CE1 1 
ATOM   1190 C  CE2 . PHE   A 1 198 ? 115.903 105.964 81.717  1.00 74.10  ? 198 PHE   A CE2 1 
ATOM   1191 C  CZ  . PHE   A 1 198 ? 115.784 106.633 80.520  1.00 74.10  ? 198 PHE   A CZ  1 
ATOM   1192 N  N   . TRP   A 1 199 ? 119.494 105.163 84.711  1.00 70.83  ? 199 TRP   A N   1 
ATOM   1193 C  CA  . TRP   A 1 199 ? 118.690 105.417 85.903  1.00 70.83  ? 199 TRP   A CA  1 
ATOM   1194 C  C   . TRP   A 1 199 ? 119.240 106.567 86.736  1.00 70.83  ? 199 TRP   A C   1 
ATOM   1195 O  O   . TRP   A 1 199 ? 118.466 107.285 87.379  1.00 70.83  ? 199 TRP   A O   1 
ATOM   1196 C  CB  . TRP   A 1 199 ? 118.602 104.147 86.751  1.00 70.83  ? 199 TRP   A CB  1 
ATOM   1197 C  CG  . TRP   A 1 199 ? 118.047 104.361 88.131  1.00 70.83  ? 199 TRP   A CG  1 
ATOM   1198 C  CD1 . TRP   A 1 199 ? 118.654 104.048 89.311  1.00 70.83  ? 199 TRP   A CD1 1 
ATOM   1199 C  CD2 . TRP   A 1 199 ? 116.769 104.916 88.473  1.00 70.83  ? 199 TRP   A CD2 1 
ATOM   1200 N  NE1 . TRP   A 1 199 ? 117.841 104.383 90.366  1.00 70.83  ? 199 TRP   A NE1 1 
ATOM   1201 C  CE2 . TRP   A 1 199 ? 116.678 104.915 89.879  1.00 70.83  ? 199 TRP   A CE2 1 
ATOM   1202 C  CE3 . TRP   A 1 199 ? 115.697 105.416 87.729  1.00 70.83  ? 199 TRP   A CE3 1 
ATOM   1203 C  CZ2 . TRP   A 1 199 ? 115.558 105.394 90.554  1.00 70.83  ? 199 TRP   A CZ2 1 
ATOM   1204 C  CZ3 . TRP   A 1 199 ? 114.587 105.892 88.403  1.00 70.83  ? 199 TRP   A CZ3 1 
ATOM   1205 C  CH2 . TRP   A 1 199 ? 114.525 105.877 89.800  1.00 70.83  ? 199 TRP   A CH2 1 
ATOM   1206 N  N   . GLU   A 1 200 ? 120.556 106.767 86.737  1.00 77.09  ? 200 GLU   A N   1 
ATOM   1207 C  CA  . GLU   A 1 200 ? 121.173 107.765 87.599  1.00 77.09  ? 200 GLU   A CA  1 
ATOM   1208 C  C   . GLU   A 1 200 ? 121.651 109.005 86.858  1.00 77.09  ? 200 GLU   A C   1 
ATOM   1209 O  O   . GLU   A 1 200 ? 122.138 109.938 87.506  1.00 77.09  ? 200 GLU   A O   1 
ATOM   1210 C  CB  . GLU   A 1 200 ? 122.347 107.148 88.370  1.00 77.09  ? 200 GLU   A CB  1 
ATOM   1211 C  CG  . GLU   A 1 200 ? 123.525 106.750 87.501  1.00 77.09  ? 200 GLU   A CG  1 
ATOM   1212 C  CD  . GLU   A 1 200 ? 124.559 105.948 88.263  1.00 77.09  ? 200 GLU   A CD  1 
ATOM   1213 O  OE1 . GLU   A 1 200 ? 124.322 105.651 89.453  1.00 77.09  ? 200 GLU   A OE1 1 
ATOM   1214 O  OE2 . GLU   A 1 200 ? 125.609 105.616 87.674  1.00 77.09  ? 200 GLU   A OE2 1 
ATOM   1215 N  N   . ARG   A 1 201 ? 121.543 109.053 85.527  1.00 75.45  ? 201 ARG   A N   1 
ATOM   1216 C  CA  . ARG   A 1 201 ? 121.931 110.260 84.810  1.00 75.45  ? 201 ARG   A CA  1 
ATOM   1217 C  C   . ARG   A 1 201 ? 120.900 110.796 83.826  1.00 75.45  ? 201 ARG   A C   1 
ATOM   1218 O  O   . ARG   A 1 201 ? 121.164 111.832 83.207  1.00 75.45  ? 201 ARG   A O   1 
ATOM   1219 C  CB  . ARG   A 1 201 ? 123.257 110.049 84.063  1.00 75.45  ? 201 ARG   A CB  1 
ATOM   1220 C  CG  . ARG   A 1 201 ? 124.268 109.198 84.806  1.00 75.45  ? 201 ARG   A CG  1 
ATOM   1221 C  CD  . ARG   A 1 201 ? 125.340 108.680 83.874  1.00 75.45  ? 201 ARG   A CD  1 
ATOM   1222 N  NE  . ARG   A 1 201 ? 126.203 109.768 83.433  1.00 75.45  ? 201 ARG   A NE  1 
ATOM   1223 C  CZ  . ARG   A 1 201 ? 127.195 110.274 84.153  1.00 75.45  ? 201 ARG   A CZ  1 
ATOM   1224 N  NH1 . ARG   A 1 201 ? 127.489 109.801 85.353  1.00 75.45  ? 201 ARG   A NH1 1 
ATOM   1225 N  NH2 . ARG   A 1 201 ? 127.910 111.279 83.657  1.00 75.45  ? 201 ARG   A NH2 1 
ATOM   1226 N  N   . ASN   A 1 202 ? 119.749 110.142 83.650  1.00 70.43  ? 202 ASN   A N   1 
ATOM   1227 C  CA  . ASN   A 1 202 ? 118.703 110.686 82.787  1.00 70.43  ? 202 ASN   A CA  1 
ATOM   1228 C  C   . ASN   A 1 202 ? 117.457 111.029 83.592  1.00 70.43  ? 202 ASN   A C   1 
ATOM   1229 O  O   . ASN   A 1 202 ? 116.995 112.171 83.534  1.00 70.43  ? 202 ASN   A O   1 
ATOM   1230 C  CB  . ASN   A 1 202 ? 118.380 109.712 81.654  1.00 70.43  ? 202 ASN   A CB  1 
ATOM   1231 C  CG  . ASN   A 1 202 ? 117.293 110.230 80.739  1.00 70.43  ? 202 ASN   A CG  1 
ATOM   1232 O  OD1 . ASN   A 1 202 ? 117.559 111.003 79.820  1.00 70.43  ? 202 ASN   A OD1 1 
ATOM   1233 N  ND2 . ASN   A 1 202 ? 116.058 109.817 80.991  1.00 70.43  ? 202 ASN   A ND2 1 
ATOM   1234 N  N   . VAL   A 1 203 ? 116.893 110.077 84.337  1.00 66.50  ? 203 VAL   A N   1 
ATOM   1235 C  CA  . VAL   A 1 203 ? 115.689 110.355 85.115  1.00 66.50  ? 203 VAL   A CA  1 
ATOM   1236 C  C   . VAL   A 1 203 ? 115.977 111.416 86.167  1.00 66.50  ? 203 VAL   A C   1 
ATOM   1237 O  O   . VAL   A 1 203 ? 115.185 112.341 86.379  1.00 66.50  ? 203 VAL   A O   1 
ATOM   1238 C  CB  . VAL   A 1 203 ? 115.151 109.061 85.752  1.00 66.50  ? 203 VAL   A CB  1 
ATOM   1239 C  CG1 . VAL   A 1 203 ? 113.793 109.307 86.393  1.00 66.50  ? 203 VAL   A CG1 1 
ATOM   1240 C  CG2 . VAL   A 1 203 ? 115.070 107.953 84.716  1.00 66.50  ? 203 VAL   A CG2 1 
ATOM   1241 N  N   . LEU   A 1 204 ? 117.120 111.298 86.839  1.00 73.18  ? 204 LEU   A N   1 
ATOM   1242 C  CA  . LEU   A 1 204 ? 117.555 112.278 87.833  1.00 73.18  ? 204 LEU   A CA  1 
ATOM   1243 C  C   . LEU   A 1 204 ? 119.080 112.247 87.850  1.00 73.18  ? 204 LEU   A C   1 
ATOM   1244 O  O   . LEU   A 1 204 ? 119.684 111.185 88.030  1.00 73.18  ? 204 LEU   A O   1 
ATOM   1245 C  CB  . LEU   A 1 204 ? 116.960 111.990 89.211  1.00 73.18  ? 204 LEU   A CB  1 
ATOM   1246 C  CG  . LEU   A 1 204 ? 117.410 110.802 90.073  1.00 73.18  ? 204 LEU   A CG  1 
ATOM   1247 C  CD1 . LEU   A 1 204 ? 116.764 110.880 91.445  1.00 73.18  ? 204 LEU   A CD1 1 
ATOM   1248 C  CD2 . LEU   A 1 204 ? 117.108 109.459 89.427  1.00 73.18  ? 204 LEU   A CD2 1 
ATOM   1249 N  N   . SER   A 1 205 ? 119.698 113.403 87.626  1.00 74.33  ? 205 SER   A N   1 
ATOM   1250 C  CA  . SER   A 1 205 ? 121.152 113.492 87.641  1.00 74.33  ? 205 SER   A CA  1 
ATOM   1251 C  C   . SER   A 1 205 ? 121.674 113.329 89.061  1.00 74.33  ? 205 SER   A C   1 
ATOM   1252 O  O   . SER   A 1 205 ? 121.156 113.943 89.998  1.00 74.33  ? 205 SER   A O   1 
ATOM   1253 C  CB  . SER   A 1 205 ? 121.599 114.831 87.054  1.00 74.33  ? 205 SER   A CB  1 
ATOM   1254 O  OG  . SER   A 1 205 ? 121.049 115.030 85.765  1.00 74.33  ? 205 SER   A OG  1 
ATOM   1255 N  N   . LEU   A 1 206 ? 122.701 112.499 89.219  1.00 73.34  ? 206 LEU   A N   1 
ATOM   1256 C  CA  . LEU   A 1 206 ? 123.210 112.171 90.544  1.00 73.34  ? 206 LEU   A CA  1 
ATOM   1257 C  C   . LEU   A 1 206 ? 124.231 113.210 90.993  1.00 73.34  ? 206 LEU   A C   1 
ATOM   1258 O  O   . LEU   A 1 206 ? 125.360 113.242 90.491  1.00 73.34  ? 206 LEU   A O   1 
ATOM   1259 C  CB  . LEU   A 1 206 ? 123.825 110.774 90.551  1.00 73.34  ? 206 LEU   A CB  1 
ATOM   1260 C  CG  . LEU   A 1 206 ? 123.708 110.024 91.880  1.00 73.34  ? 206 LEU   A CG  1 
ATOM   1261 C  CD1 . LEU   A 1 206 ? 122.265 109.986 92.358  1.00 73.34  ? 206 LEU   A CD1 1 
ATOM   1262 C  CD2 . LEU   A 1 206 ? 124.275 108.619 91.758  1.00 73.34  ? 206 LEU   A CD2 1 
ATOM   1263 N  N   . SER   A 1 207 ? 123.829 114.055 91.935  1.00 73.58  ? 207 SER   A N   1 
ATOM   1264 C  CA  . SER   A 1 207 ? 124.733 114.976 92.603  1.00 73.58  ? 207 SER   A CA  1 
ATOM   1265 C  C   . SER   A 1 207 ? 125.694 114.187 93.485  1.00 73.58  ? 207 SER   A C   1 
ATOM   1266 O  O   . SER   A 1 207 ? 125.369 113.096 93.957  1.00 73.58  ? 207 SER   A O   1 
ATOM   1267 C  CB  . SER   A 1 207 ? 123.917 115.981 93.415  1.00 73.58  ? 207 SER   A CB  1 
ATOM   1268 O  OG  . SER   A 1 207 ? 124.728 116.942 94.064  1.00 73.58  ? 207 SER   A OG  1 
ATOM   1269 N  N   . PRO   A 1 208 ? 126.902 114.707 93.723  1.00 77.49  ? 208 PRO   A N   1 
ATOM   1270 C  CA  . PRO   A 1 208 ? 127.858 113.955 94.554  1.00 77.49  ? 208 PRO   A CA  1 
ATOM   1271 C  C   . PRO   A 1 208 ? 127.426 113.795 96.002  1.00 77.49  ? 208 PRO   A C   1 
ATOM   1272 O  O   . PRO   A 1 208 ? 128.036 113.001 96.730  1.00 77.49  ? 208 PRO   A O   1 
ATOM   1273 C  CB  . PRO   A 1 208 ? 129.151 114.779 94.425  1.00 77.49  ? 208 PRO   A CB  1 
ATOM   1274 C  CG  . PRO   A 1 208 ? 128.921 115.656 93.216  1.00 77.49  ? 208 PRO   A CG  1 
ATOM   1275 C  CD  . PRO   A 1 208 ? 127.480 115.992 93.304  1.00 77.49  ? 208 PRO   A CD  1 
ATOM   1276 N  N   . GLY   A 1 209 ? 126.406 114.517 96.450  1.00 72.16  ? 209 GLY   A N   1 
ATOM   1277 C  CA  . GLY   A 1 209 ? 125.907 114.322 97.795  1.00 72.16  ? 209 GLY   A CA  1 
ATOM   1278 C  C   . GLY   A 1 209 ? 124.728 115.230 98.080  1.00 72.16  ? 209 GLY   A C   1 
ATOM   1279 O  O   . GLY   A 1 209 ? 124.411 116.134 97.304  1.00 72.16  ? 209 GLY   A O   1 
ATOM   1280 N  N   . ILE   A 1 210 ? 124.083 114.960 99.218  1.00 67.69  ? 210 ILE   A N   1 
ATOM   1281 C  CA  . ILE   A 1 210 ? 122.993 115.804 99.693  1.00 67.69  ? 210 ILE   A CA  1 
ATOM   1282 C  C   . ILE   A 1 210 ? 123.492 117.191 100.072 1.00 67.69  ? 210 ILE   A C   1 
ATOM   1283 O  O   . ILE   A 1 210 ? 122.728 118.161 100.024 1.00 67.69  ? 210 ILE   A O   1 
ATOM   1284 C  CB  . ILE   A 1 210 ? 122.275 115.125 100.880 1.00 67.69  ? 210 ILE   A CB  1 
ATOM   1285 C  CG1 . ILE   A 1 210 ? 121.012 115.896 101.267 1.00 67.69  ? 210 ILE   A CG1 1 
ATOM   1286 C  CG2 . ILE   A 1 210 ? 123.210 114.989 102.072 1.00 67.69  ? 210 ILE   A CG2 1 
ATOM   1287 C  CD1 . ILE   A 1 210 ? 120.139 115.172 102.263 1.00 67.69  ? 210 ILE   A CD1 1 
ATOM   1288 N  N   . ASP   A 1 211 ? 124.770 117.313 100.441 1.00 76.73  ? 211 ASP   A N   1 
ATOM   1289 C  CA  . ASP   A 1 211 ? 125.301 118.605 100.862 1.00 76.73  ? 211 ASP   A CA  1 
ATOM   1290 C  C   . ASP   A 1 211 ? 125.364 119.588 99.700  1.00 76.73  ? 211 ASP   A C   1 
ATOM   1291 O  O   . ASP   A 1 211 ? 125.499 120.799 99.909  1.00 76.73  ? 211 ASP   A O   1 
ATOM   1292 C  CB  . ASP   A 1 211 ? 126.683 118.424 101.489 1.00 76.73  ? 211 ASP   A CB  1 
ATOM   1293 C  CG  . ASP   A 1 211 ? 127.741 118.053 100.469 1.00 76.73  ? 211 ASP   A CG  1 
ATOM   1294 O  OD1 . ASP   A 1 211 ? 127.402 117.378 99.475  1.00 76.73  ? 211 ASP   A OD1 1 
ATOM   1295 O  OD2 . ASP   A 1 211 ? 128.914 118.434 100.664 1.00 76.73  ? 211 ASP   A OD2 1 
ATOM   1296 N  N   . HIS   A 1 212 ? 125.262 119.089 98.467  1.00 78.00  ? 212 HIS   A N   1 
ATOM   1297 C  CA  . HIS   A 1 212 ? 125.370 119.920 97.271  1.00 78.00  ? 212 HIS   A CA  1 
ATOM   1298 C  C   . HIS   A 1 212 ? 124.131 119.751 96.402  1.00 78.00  ? 212 HIS   A C   1 
ATOM   1299 O  O   . HIS   A 1 212 ? 124.179 119.068 95.368  1.00 78.00  ? 212 HIS   A O   1 
ATOM   1300 C  CB  . HIS   A 1 212 ? 126.633 119.562 96.484  1.00 78.00  ? 212 HIS   A CB  1 
ATOM   1301 C  CG  . HIS   A 1 212 ? 127.852 120.310 96.925  1.00 78.00  ? 212 HIS   A CG  1 
ATOM   1302 N  ND1 . HIS   A 1 212 ? 127.838 121.660 97.201  1.00 78.00  ? 212 HIS   A ND1 1 
ATOM   1303 C  CD2 . HIS   A 1 212 ? 129.124 119.896 97.136  1.00 78.00  ? 212 HIS   A CD2 1 
ATOM   1304 C  CE1 . HIS   A 1 212 ? 129.048 122.046 97.564  1.00 78.00  ? 212 HIS   A CE1 1 
ATOM   1305 N  NE2 . HIS   A 1 212 ? 129.847 120.995 97.533  1.00 78.00  ? 212 HIS   A NE2 1 
ATOM   1306 N  N   . PRO   A 1 213 ? 122.999 120.346 96.769  1.00 72.31  ? 213 PRO   A N   1 
ATOM   1307 C  CA  . PRO   A 1 213 ? 121.831 120.325 95.883  1.00 72.31  ? 213 PRO   A CA  1 
ATOM   1308 C  C   . PRO   A 1 213 ? 122.095 121.138 94.626  1.00 72.31  ? 213 PRO   A C   1 
ATOM   1309 O  O   . PRO   A 1 213 ? 122.925 122.049 94.596  1.00 72.31  ? 213 PRO   A O   1 
ATOM   1310 C  CB  . PRO   A 1 213 ? 120.720 120.950 96.733  1.00 72.31  ? 213 PRO   A CB  1 
ATOM   1311 C  CG  . PRO   A 1 213 ? 121.212 120.852 98.146  1.00 72.31  ? 213 PRO   A CG  1 
ATOM   1312 C  CD  . PRO   A 1 213 ? 122.695 121.007 98.048  1.00 72.31  ? 213 PRO   A CD  1 
ATOM   1313 N  N   . GLY   A 1 214 ? 121.369 120.792 93.568  1.00 70.55  ? 214 GLY   A N   1 
ATOM   1314 C  CA  . GLY   A 1 214 ? 121.573 121.442 92.289  1.00 70.55  ? 214 GLY   A CA  1 
ATOM   1315 C  C   . GLY   A 1 214 ? 120.384 122.239 91.793  1.00 70.55  ? 214 GLY   A C   1 
ATOM   1316 O  O   . GLY   A 1 214 ? 119.709 122.917 92.573  1.00 70.55  ? 214 GLY   A O   1 
ATOM   1317 N  N   . SER   A 1 215 ? 120.123 122.162 90.492  1.00 68.86  ? 215 SER   A N   1 
ATOM   1318 C  CA  . SER   A 1 215 ? 119.064 122.928 89.851  1.00 68.86  ? 215 SER   A CA  1 
ATOM   1319 C  C   . SER   A 1 215 ? 117.812 122.071 89.721  1.00 68.86  ? 215 SER   A C   1 
ATOM   1320 O  O   . SER   A 1 215 ? 117.893 120.896 89.349  1.00 68.86  ? 215 SER   A O   1 
ATOM   1321 C  CB  . SER   A 1 215 ? 119.512 123.422 88.475  1.00 68.86  ? 215 SER   A CB  1 
ATOM   1322 O  OG  . SER   A 1 215 ? 120.209 122.407 87.775  1.00 68.86  ? 215 SER   A OG  1 
ATOM   1323 N  N   . LEU   A 1 216 ? 116.662 122.664 90.031  1.00 64.96  ? 216 LEU   A N   1 
ATOM   1324 C  CA  . LEU   A 1 216 ? 115.389 121.961 89.951  1.00 64.96  ? 216 LEU   A CA  1 
ATOM   1325 C  C   . LEU   A 1 216 ? 115.103 121.507 88.528  1.00 64.96  ? 216 LEU   A C   1 
ATOM   1326 O  O   . LEU   A 1 216 ? 115.073 122.320 87.600  1.00 64.96  ? 216 LEU   A O   1 
ATOM   1327 C  CB  . LEU   A 1 216 ? 114.269 122.874 90.452  1.00 64.96  ? 216 LEU   A CB  1 
ATOM   1328 C  CG  . LEU   A 1 216 ? 112.823 122.467 90.164  1.00 64.96  ? 216 LEU   A CG  1 
ATOM   1329 C  CD1 . LEU   A 1 216 ? 112.504 121.104 90.747  1.00 64.96  ? 216 LEU   A CD1 1 
ATOM   1330 C  CD2 . LEU   A 1 216 ? 111.864 123.517 90.702  1.00 64.96  ? 216 LEU   A CD2 1 
ATOM   1331 N  N   . LYS   A 1 217 ? 114.893 120.204 88.360  1.00 65.72  ? 217 LYS   A N   1 
ATOM   1332 C  CA  . LYS   A 1 217 ? 114.519 119.671 87.058  1.00 65.72  ? 217 LYS   A CA  1 
ATOM   1333 C  C   . LYS   A 1 217 ? 113.049 119.953 86.779  1.00 65.72  ? 217 LYS   A C   1 
ATOM   1334 O  O   . LYS   A 1 217 ? 112.211 119.927 87.685  1.00 65.72  ? 217 LYS   A O   1 
ATOM   1335 C  CB  . LYS   A 1 217 ? 114.792 118.170 86.994  1.00 65.72  ? 217 LYS   A CB  1 
ATOM   1336 C  CG  . LYS   A 1 217 ? 116.253 117.819 86.783  1.00 65.72  ? 217 LYS   A CG  1 
ATOM   1337 C  CD  . LYS   A 1 217 ? 116.423 116.354 86.431  1.00 65.72  ? 217 LYS   A CD  1 
ATOM   1338 C  CE  . LYS   A 1 217 ? 115.513 115.956 85.283  1.00 65.72  ? 217 LYS   A CE  1 
ATOM   1339 N  NZ  . LYS   A 1 217 ? 116.169 114.986 84.365  1.00 65.72  ? 217 LYS   A NZ  1 
ATOM   1340 N  N   . TRP   A 1 218 ? 112.735 120.222 85.513  1.00 73.69  ? 218 TRP   A N   1 
ATOM   1341 C  CA  . TRP   A 1 218 ? 111.384 120.605 85.128  1.00 73.69  ? 218 TRP   A CA  1 
ATOM   1342 C  C   . TRP   A 1 218 ? 110.550 119.447 84.599  1.00 73.69  ? 218 TRP   A C   1 
ATOM   1343 O  O   . TRP   A 1 218 ? 109.325 119.465 84.764  1.00 73.69  ? 218 TRP   A O   1 
ATOM   1344 C  CB  . TRP   A 1 218 ? 111.434 121.717 84.074  1.00 73.69  ? 218 TRP   A CB  1 
ATOM   1345 C  CG  . TRP   A 1 218 ? 112.059 122.978 84.585  1.00 73.69  ? 218 TRP   A CG  1 
ATOM   1346 C  CD1 . TRP   A 1 218 ? 113.301 123.455 84.287  1.00 73.69  ? 218 TRP   A CD1 1 
ATOM   1347 C  CD2 . TRP   A 1 218 ? 111.475 123.919 85.493  1.00 73.69  ? 218 TRP   A CD2 1 
ATOM   1348 N  NE1 . TRP   A 1 218 ? 113.526 124.636 84.950  1.00 73.69  ? 218 TRP   A NE1 1 
ATOM   1349 C  CE2 . TRP   A 1 218 ? 112.420 124.944 85.697  1.00 73.69  ? 218 TRP   A CE2 1 
ATOM   1350 C  CE3 . TRP   A 1 218 ? 110.244 123.997 86.151  1.00 73.69  ? 218 TRP   A CE3 1 
ATOM   1351 C  CZ2 . TRP   A 1 218 ? 112.173 126.032 86.531  1.00 73.69  ? 218 TRP   A CZ2 1 
ATOM   1352 C  CZ3 . TRP   A 1 218 ? 110.001 125.079 86.979  1.00 73.69  ? 218 TRP   A CZ3 1 
ATOM   1353 C  CH2 . TRP   A 1 218 ? 110.961 126.081 87.161  1.00 73.69  ? 218 TRP   A CH2 1 
ATOM   1354 N  N   . ASP   A 1 219 ? 111.175 118.443 83.981  1.00 66.39  ? 219 ASP   A N   1 
ATOM   1355 C  CA  . ASP   A 1 219 ? 110.417 117.314 83.451  1.00 66.39  ? 219 ASP   A CA  1 
ATOM   1356 C  C   . ASP   A 1 219 ? 109.700 116.559 84.563  1.00 66.39  ? 219 ASP   A C   1 
ATOM   1357 O  O   . ASP   A 1 219 ? 108.489 116.314 84.484  1.00 66.39  ? 219 ASP   A O   1 
ATOM   1358 C  CB  . ASP   A 1 219 ? 111.348 116.377 82.683  1.00 66.39  ? 219 ASP   A CB  1 
ATOM   1359 C  CG  . ASP   A 1 219 ? 111.862 116.993 81.401  1.00 66.39  ? 219 ASP   A CG  1 
ATOM   1360 O  OD1 . ASP   A 1 219 ? 111.149 117.833 80.816  1.00 66.39  ? 219 ASP   A OD1 1 
ATOM   1361 O  OD2 . ASP   A 1 219 ? 112.980 116.634 80.976  1.00 66.39  ? 219 ASP   A OD2 1 
ATOM   1362 N  N   . LEU   A 1 220 ? 110.435 116.184 85.613  1.00 62.45  ? 220 LEU   A N   1 
ATOM   1363 C  CA  . LEU   A 1 220 ? 109.825 115.451 86.716  1.00 62.45  ? 220 LEU   A CA  1 
ATOM   1364 C  C   . LEU   A 1 220 ? 108.815 116.306 87.466  1.00 62.45  ? 220 LEU   A C   1 
ATOM   1365 O  O   . LEU   A 1 220 ? 107.790 115.790 87.922  1.00 62.45  ? 220 LEU   A O   1 
ATOM   1366 C  CB  . LEU   A 1 220 ? 110.903 114.940 87.669  1.00 62.45  ? 220 LEU   A CB  1 
ATOM   1367 C  CG  . LEU   A 1 220 ? 111.834 113.866 87.107  1.00 62.45  ? 220 LEU   A CG  1 
ATOM   1368 C  CD1 . LEU   A 1 220 ? 112.651 113.240 88.221  1.00 62.45  ? 220 LEU   A CD1 1 
ATOM   1369 C  CD2 . LEU   A 1 220 ? 111.040 112.808 86.364  1.00 62.45  ? 220 LEU   A CD2 1 
ATOM   1370 N  N   . ALA   A 1 221 ? 109.081 117.607 87.602  1.00 64.62  ? 221 ALA   A N   1 
ATOM   1371 C  CA  . ALA   A 1 221 ? 108.116 118.490 88.249  1.00 64.62  ? 221 ALA   A CA  1 
ATOM   1372 C  C   . ALA   A 1 221 ? 106.810 118.544 87.467  1.00 64.62  ? 221 ALA   A C   1 
ATOM   1373 O  O   . ALA   A 1 221 ? 105.723 118.480 88.054  1.00 64.62  ? 221 ALA   A O   1 
ATOM   1374 C  CB  . ALA   A 1 221 ? 108.708 119.889 88.409  1.00 64.62  ? 221 ALA   A CB  1 
ATOM   1375 N  N   . LEU   A 1 222 ? 106.894 118.646 86.138  1.00 66.68  ? 222 LEU   A N   1 
ATOM   1376 C  CA  . LEU   A 1 222 ? 105.681 118.663 85.328  1.00 66.68  ? 222 LEU   A CA  1 
ATOM   1377 C  C   . LEU   A 1 222 ? 104.953 117.326 85.388  1.00 66.68  ? 222 LEU   A C   1 
ATOM   1378 O  O   . LEU   A 1 222 ? 103.719 117.291 85.450  1.00 66.68  ? 222 LEU   A O   1 
ATOM   1379 C  CB  . LEU   A 1 222 ? 106.013 119.038 83.885  1.00 66.68  ? 222 LEU   A CB  1 
ATOM   1380 C  CG  . LEU   A 1 222 ? 106.460 120.487 83.676  1.00 66.68  ? 222 LEU   A CG  1 
ATOM   1381 C  CD1 . LEU   A 1 222 ? 106.860 120.731 82.228  1.00 66.68  ? 222 LEU   A CD1 1 
ATOM   1382 C  CD2 . LEU   A 1 222 ? 105.368 121.454 84.107  1.00 66.68  ? 222 LEU   A CD2 1 
ATOM   1383 N  N   . CYS   A 1 223 ? 105.693 116.214 85.376  1.00 65.18  ? 223 CYS   A N   1 
ATOM   1384 C  CA  . CYS   A 1 223 ? 105.048 114.907 85.482  1.00 65.18  ? 223 CYS   A CA  1 
ATOM   1385 C  C   . CYS   A 1 223 ? 104.334 114.748 86.821  1.00 65.18  ? 223 CYS   A C   1 
ATOM   1386 O  O   . CYS   A 1 223 ? 103.216 114.220 86.883  1.00 65.18  ? 223 CYS   A O   1 
ATOM   1387 C  CB  . CYS   A 1 223 ? 106.075 113.793 85.286  1.00 65.18  ? 223 CYS   A CB  1 
ATOM   1388 S  SG  . CYS   A 1 223 ? 106.790 113.714 83.629  1.00 65.18  ? 223 CYS   A SG  1 
ATOM   1389 N  N   . LEU   A 1 224 ? 104.960 115.208 87.906  1.00 59.18  ? 224 LEU   A N   1 
ATOM   1390 C  CA  . LEU   A 1 224 ? 104.342 115.086 89.221  1.00 59.18  ? 224 LEU   A CA  1 
ATOM   1391 C  C   . LEU   A 1 224 ? 103.140 116.016 89.355  1.00 59.18  ? 224 LEU   A C   1 
ATOM   1392 O  O   . LEU   A 1 224 ? 102.143 115.657 89.995  1.00 59.18  ? 224 LEU   A O   1 
ATOM   1393 C  CB  . LEU   A 1 224 ? 105.393 115.349 90.302  1.00 59.18  ? 224 LEU   A CB  1 
ATOM   1394 C  CG  . LEU   A 1 224 ? 105.083 115.115 91.783  1.00 59.18  ? 224 LEU   A CG  1 
ATOM   1395 C  CD1 . LEU   A 1 224 ? 106.372 114.804 92.518  1.00 59.18  ? 224 LEU   A CD1 1 
ATOM   1396 C  CD2 . LEU   A 1 224 ? 104.413 116.307 92.418  1.00 59.18  ? 224 LEU   A CD2 1 
ATOM   1397 N  N   . LEU   A 1 225 ? 103.204 117.203 88.744  1.00 65.94  ? 225 LEU   A N   1 
ATOM   1398 C  CA  . LEU   A 1 225 ? 102.031 118.070 88.692  1.00 65.94  ? 225 LEU   A CA  1 
ATOM   1399 C  C   . LEU   A 1 225 ? 100.900 117.419 87.904  1.00 65.94  ? 225 LEU   A C   1 
ATOM   1400 O  O   . LEU   A 1 225 ? 99.726  117.548 88.266  1.00 65.94  ? 225 LEU   A O   1 
ATOM   1401 C  CB  . LEU   A 1 225 ? 102.401 119.422 88.082  1.00 65.94  ? 225 LEU   A CB  1 
ATOM   1402 C  CG  . LEU   A 1 225 ? 101.235 120.359 87.762  1.00 65.94  ? 225 LEU   A CG  1 
ATOM   1403 C  CD1 . LEU   A 1 225 ? 100.777 121.092 89.011  1.00 65.94  ? 225 LEU   A CD1 1 
ATOM   1404 C  CD2 . LEU   A 1 225 ? 101.619 121.343 86.673  1.00 65.94  ? 225 LEU   A CD2 1 
ATOM   1405 N  N   . LEU   A 1 226 ? 101.235 116.724 86.816  1.00 67.00  ? 226 LEU   A N   1 
ATOM   1406 C  CA  . LEU   A 1 226 ? 100.219 115.996 86.064  1.00 67.00  ? 226 LEU   A CA  1 
ATOM   1407 C  C   . LEU   A 1 226 ? 99.589  114.901 86.915  1.00 67.00  ? 226 LEU   A C   1 
ATOM   1408 O  O   . LEU   A 1 226 ? 98.375  114.678 86.854  1.00 67.00  ? 226 LEU   A O   1 
ATOM   1409 C  CB  . LEU   A 1 226 ? 100.832 115.413 84.789  1.00 67.00  ? 226 LEU   A CB  1 
ATOM   1410 C  CG  . LEU   A 1 226 ? 99.902  114.806 83.733  1.00 67.00  ? 226 LEU   A CG  1 
ATOM   1411 C  CD1 . LEU   A 1 226 ? 100.487 115.017 82.348  1.00 67.00  ? 226 LEU   A CD1 1 
ATOM   1412 C  CD2 . LEU   A 1 226 ? 99.672  113.322 83.982  1.00 67.00  ? 226 LEU   A CD2 1 
ATOM   1413 N  N   . VAL   A 1 227 ? 100.403 114.199 87.706  1.00 66.44  ? 227 VAL   A N   1 
ATOM   1414 C  CA  . VAL   A 1 227 ? 99.868  113.179 88.607  1.00 66.44  ? 227 VAL   A CA  1 
ATOM   1415 C  C   . VAL   A 1 227 ? 98.913  113.808 89.615  1.00 66.44  ? 227 VAL   A C   1 
ATOM   1416 O  O   . VAL   A 1 227 ? 97.832  113.270 89.894  1.00 66.44  ? 227 VAL   A O   1 
ATOM   1417 C  CB  . VAL   A 1 227 ? 101.013 112.423 89.307  1.00 66.44  ? 227 VAL   A CB  1 
ATOM   1418 C  CG1 . VAL   A 1 227 ? 100.467 111.541 90.414  1.00 66.44  ? 227 VAL   A CG1 1 
ATOM   1419 C  CG2 . VAL   A 1 227 ? 101.794 111.593 88.304  1.00 66.44  ? 227 VAL   A CG2 1 
ATOM   1420 N  N   . TRP   A 1 228 ? 99.290  114.960 90.173  1.00 65.95  ? 228 TRP   A N   1 
ATOM   1421 C  CA  . TRP   A 1 228 ? 98.398  115.652 91.098  1.00 65.95  ? 228 TRP   A CA  1 
ATOM   1422 C  C   . TRP   A 1 228 ? 97.113  116.122 90.428  1.00 65.95  ? 228 TRP   A C   1 
ATOM   1423 O  O   . TRP   A 1 228 ? 96.052  116.084 91.060  1.00 65.95  ? 228 TRP   A O   1 
ATOM   1424 C  CB  . TRP   A 1 228 ? 99.111  116.839 91.746  1.00 65.95  ? 228 TRP   A CB  1 
ATOM   1425 C  CG  . TRP   A 1 228 ? 99.787  116.474 93.028  1.00 65.95  ? 228 TRP   A CG  1 
ATOM   1426 C  CD1 . TRP   A 1 228 ? 101.127 116.375 93.248  1.00 65.95  ? 228 TRP   A CD1 1 
ATOM   1427 C  CD2 . TRP   A 1 228 ? 99.151  116.134 94.264  1.00 65.95  ? 228 TRP   A CD2 1 
ATOM   1428 N  NE1 . TRP   A 1 228 ? 101.368 116.005 94.548  1.00 65.95  ? 228 TRP   A NE1 1 
ATOM   1429 C  CE2 . TRP   A 1 228 ? 100.169 115.849 95.192  1.00 65.95  ? 228 TRP   A CE2 1 
ATOM   1430 C  CE3 . TRP   A 1 228 ? 97.819  116.048 94.678  1.00 65.95  ? 228 TRP   A CE3 1 
ATOM   1431 C  CZ2 . TRP   A 1 228 ? 99.898  115.481 96.506  1.00 65.95  ? 228 TRP   A CZ2 1 
ATOM   1432 C  CZ3 . TRP   A 1 228 ? 97.553  115.683 95.982  1.00 65.95  ? 228 TRP   A CZ3 1 
ATOM   1433 C  CH2 . TRP   A 1 228 ? 98.586  115.407 96.881  1.00 65.95  ? 228 TRP   A CH2 1 
ATOM   1434 N  N   . LEU   A 1 229 ? 97.176  116.562 89.174  1.00 74.26  ? 229 LEU   A N   1 
ATOM   1435 C  CA  . LEU   A 1 229 ? 95.973  116.934 88.441  1.00 74.26  ? 229 LEU   A CA  1 
ATOM   1436 C  C   . LEU   A 1 229 ? 95.074  115.744 88.141  1.00 74.26  ? 229 LEU   A C   1 
ATOM   1437 O  O   . LEU   A 1 229 ? 93.848  115.892 88.171  1.00 74.26  ? 229 LEU   A O   1 
ATOM   1438 C  CB  . LEU   A 1 229 ? 96.336  117.636 87.130  1.00 74.26  ? 229 LEU   A CB  1 
ATOM   1439 C  CG  . LEU   A 1 229 ? 96.927  119.038 87.264  1.00 74.26  ? 229 LEU   A CG  1 
ATOM   1440 C  CD1 . LEU   A 1 229 ? 97.343  119.570 85.904  1.00 74.26  ? 229 LEU   A CD1 1 
ATOM   1441 C  CD2 . LEU   A 1 229 ? 95.928  119.971 87.927  1.00 74.26  ? 229 LEU   A CD2 1 
ATOM   1442 N  N   . VAL   A 1 230 ? 95.647  114.576 87.856  1.00 70.92  ? 230 VAL   A N   1 
ATOM   1443 C  CA  . VAL   A 1 230 ? 94.868  113.353 87.708  1.00 70.92  ? 230 VAL   A CA  1 
ATOM   1444 C  C   . VAL   A 1 230 ? 94.231  112.933 89.027  1.00 70.92  ? 230 VAL   A C   1 
ATOM   1445 O  O   . VAL   A 1 230 ? 93.112  112.412 89.035  1.00 70.92  ? 230 VAL   A O   1 
ATOM   1446 C  CB  . VAL   A 1 230 ? 95.723  112.216 87.123  1.00 70.92  ? 230 VAL   A CB  1 
ATOM   1447 C  CG1 . VAL   A 1 230 ? 94.902  110.945 86.980  1.00 70.92  ? 230 VAL   A CG1 1 
ATOM   1448 C  CG2 . VAL   A 1 230 ? 96.285  112.620 85.773  1.00 70.92  ? 230 VAL   A CG2 1 
ATOM   1449 N  N   . CYS   A 1 231 ? 94.912  113.165 90.150  1.00 73.75  ? 231 CYS   A N   1 
ATOM   1450 C  CA  . CYS   A 1 231 ? 94.367  112.827 91.458  1.00 73.75  ? 231 CYS   A CA  1 
ATOM   1451 C  C   . CYS   A 1 231 ? 93.332  113.814 91.983  1.00 73.75  ? 231 CYS   A C   1 
ATOM   1452 O  O   . CYS   A 1 231 ? 92.461  113.404 92.754  1.00 73.75  ? 231 CYS   A O   1 
ATOM   1453 C  CB  . CYS   A 1 231 ? 95.496  112.704 92.493  1.00 73.75  ? 231 CYS   A CB  1 
ATOM   1454 S  SG  . CYS   A 1 231 ? 94.972  112.112 94.117  1.00 73.75  ? 231 CYS   A SG  1 
ATOM   1455 N  N   . PHE   A 1 232 ? 93.389  115.085 91.589  1.00 85.39  ? 232 PHE   A N   1 
ATOM   1456 C  CA  . PHE   A 1 232 ? 92.495  116.115 92.116  1.00 85.39  ? 232 PHE   A CA  1 
ATOM   1457 C  C   . PHE   A 1 232 ? 91.105  116.028 91.484  1.00 85.39  ? 232 PHE   A C   1 
ATOM   1458 O  O   . PHE   A 1 232 ? 90.086  116.008 92.191  1.00 85.39  ? 232 PHE   A O   1 
ATOM   1459 C  CB  . PHE   A 1 232 ? 93.154  117.484 91.894  1.00 85.39  ? 232 PHE   A CB  1 
ATOM   1460 C  CG  . PHE   A 1 232 ? 92.292  118.665 92.248  1.00 85.39  ? 232 PHE   A CG  1 
ATOM   1461 C  CD1 . PHE   A 1 232 ? 91.460  119.251 91.310  1.00 85.39  ? 232 PHE   A CD1 1 
ATOM   1462 C  CD2 . PHE   A 1 232 ? 92.336  119.205 93.521  1.00 85.39  ? 232 PHE   A CD2 1 
ATOM   1463 C  CE1 . PHE   A 1 232 ? 90.689  120.353 91.643  1.00 85.39  ? 232 PHE   A CE1 1 
ATOM   1464 C  CE2 . PHE   A 1 232 ? 91.560  120.298 93.857  1.00 85.39  ? 232 PHE   A CE2 1 
ATOM   1465 C  CZ  . PHE   A 1 232 ? 90.733  120.868 92.919  1.00 85.39  ? 232 PHE   A CZ  1 
ATOM   1466 N  N   . PHE   A 1 233 ? 91.055  115.968 90.149  1.00 89.69  ? 233 PHE   A N   1 
ATOM   1467 C  CA  . PHE   A 1 233 ? 89.786  115.783 89.454  1.00 89.69  ? 233 PHE   A CA  1 
ATOM   1468 C  C   . PHE   A 1 233 ? 89.143  114.454 89.817  1.00 89.69  ? 233 PHE   A C   1 
ATOM   1469 O  O   . PHE   A 1 233 ? 87.911  114.350 89.861  1.00 89.69  ? 233 PHE   A O   1 
ATOM   1470 C  CB  . PHE   A 1 233 ? 89.996  115.861 87.942  1.00 89.69  ? 233 PHE   A CB  1 
ATOM   1471 C  CG  . PHE   A 1 233 ? 90.294  117.242 87.439  1.00 89.69  ? 233 PHE   A CG  1 
ATOM   1472 C  CD1 . PHE   A 1 233 ? 89.396  118.274 87.637  1.00 89.69  ? 233 PHE   A CD1 1 
ATOM   1473 C  CD2 . PHE   A 1 233 ? 91.470  117.506 86.758  1.00 89.69  ? 233 PHE   A CD2 1 
ATOM   1474 C  CE1 . PHE   A 1 233 ? 89.666  119.547 87.175  1.00 89.69  ? 233 PHE   A CE1 1 
ATOM   1475 C  CE2 . PHE   A 1 233 ? 91.747  118.776 86.291  1.00 89.69  ? 233 PHE   A CE2 1 
ATOM   1476 C  CZ  . PHE   A 1 233 ? 90.843  119.798 86.500  1.00 89.69  ? 233 PHE   A CZ  1 
ATOM   1477 N  N   . CYS   A 1 234 ? 89.952  113.431 90.081  1.00 91.45  ? 234 CYS   A N   1 
ATOM   1478 C  CA  . CYS   A 1 234 ? 89.436  112.134 90.494  1.00 91.45  ? 234 CYS   A CA  1 
ATOM   1479 C  C   . CYS   A 1 234 ? 88.868  112.156 91.907  1.00 91.45  ? 234 CYS   A C   1 
ATOM   1480 O  O   . CYS   A 1 234 ? 88.188  111.201 92.299  1.00 91.45  ? 234 CYS   A O   1 
ATOM   1481 C  CB  . CYS   A 1 234 ? 90.539  111.076 90.385  1.00 91.45  ? 234 CYS   A CB  1 
ATOM   1482 S  SG  . CYS   A 1 234 ? 90.018  109.369 90.689  1.00 91.45  ? 234 CYS   A SG  1 
ATOM   1483 N  N   . ILE   A 1 235 ? 89.112  113.216 92.675  1.00 90.61  ? 235 ILE   A N   1 
ATOM   1484 C  CA  . ILE   A 1 235 ? 88.569  113.350 94.017  1.00 90.61  ? 235 ILE   A CA  1 
ATOM   1485 C  C   . ILE   A 1 235 ? 87.344  114.255 94.048  1.00 90.61  ? 235 ILE   A C   1 
ATOM   1486 O  O   . ILE   A 1 235 ? 86.319  113.878 94.621  1.00 90.61  ? 235 ILE   A O   1 
ATOM   1487 C  CB  . ILE   A 1 235 ? 89.638  113.837 95.021  1.00 90.61  ? 235 ILE   A CB  1 
ATOM   1488 C  CG1 . ILE   A 1 235 ? 90.749  112.797 95.165  1.00 90.61  ? 235 ILE   A CG1 1 
ATOM   1489 C  CG2 . ILE   A 1 235 ? 89.008  114.140 96.372  1.00 90.61  ? 235 ILE   A CG2 1 
ATOM   1490 C  CD1 . ILE   A 1 235 ? 90.267  111.459 95.686  1.00 90.61  ? 235 ILE   A CD1 1 
ATOM   1491 N  N   . TRP   A 1 236 ? 87.408  115.448 93.446  1.00 98.69  ? 236 TRP   A N   1 
ATOM   1492 C  CA  . TRP   A 1 236 ? 86.242  116.313 93.630  1.00 98.69  ? 236 TRP   A CA  1 
ATOM   1493 C  C   . TRP   A 1 236 ? 85.137  115.971 92.636  1.00 98.69  ? 236 TRP   A C   1 
ATOM   1494 O  O   . TRP   A 1 236 ? 84.019  116.483 92.756  1.00 98.69  ? 236 TRP   A O   1 
ATOM   1495 C  CB  . TRP   A 1 236 ? 86.618  117.793 93.538  1.00 98.69  ? 236 TRP   A CB  1 
ATOM   1496 C  CG  . TRP   A 1 236 ? 87.046  118.299 92.210  1.00 98.69  ? 236 TRP   A CG  1 
ATOM   1497 C  CD1 . TRP   A 1 236 ? 88.290  118.248 91.672  1.00 98.69  ? 236 TRP   A CD1 1 
ATOM   1498 C  CD2 . TRP   A 1 236 ? 86.253  119.087 91.311  1.00 98.69  ? 236 TRP   A CD2 1 
ATOM   1499 N  NE1 . TRP   A 1 236 ? 88.306  118.879 90.451  1.00 98.69  ? 236 TRP   A NE1 1 
ATOM   1500 C  CE2 . TRP   A 1 236 ? 87.068  119.413 90.212  1.00 98.69  ? 236 TRP   A CE2 1 
ATOM   1501 C  CE3 . TRP   A 1 236 ? 84.922  119.518 91.316  1.00 98.69  ? 236 TRP   A CE3 1 
ATOM   1502 C  CZ2 . TRP   A 1 236 ? 86.600  120.150 89.126  1.00 98.69  ? 236 TRP   A CZ2 1 
ATOM   1503 C  CZ3 . TRP   A 1 236 ? 84.458  120.250 90.237  1.00 98.69  ? 236 TRP   A CZ3 1 
ATOM   1504 C  CH2 . TRP   A 1 236 ? 85.297  120.563 89.160  1.00 98.69  ? 236 TRP   A CH2 1 
ATOM   1505 N  N   . LYS   A 1 237 ? 85.435  115.123 91.653  1.00 100.84 ? 237 LYS   A N   1 
ATOM   1506 C  CA  . LYS   A 1 237 ? 84.431  114.404 90.880  1.00 100.84 ? 237 LYS   A CA  1 
ATOM   1507 C  C   . LYS   A 1 237 ? 84.546  112.914 91.167  1.00 100.84 ? 237 LYS   A C   1 
ATOM   1508 O  O   . LYS   A 1 237 ? 85.653  112.389 91.328  1.00 100.84 ? 237 LYS   A O   1 
ATOM   1509 C  CB  . LYS   A 1 237 ? 84.572  114.624 89.368  1.00 100.84 ? 237 LYS   A CB  1 
ATOM   1510 C  CG  . LYS   A 1 237 ? 84.976  116.004 88.906  1.00 100.84 ? 237 LYS   A CG  1 
ATOM   1511 C  CD  . LYS   A 1 237 ? 83.775  116.674 88.253  1.00 100.84 ? 237 LYS   A CD  1 
ATOM   1512 C  CE  . LYS   A 1 237 ? 84.158  117.930 87.500  1.00 100.84 ? 237 LYS   A CE  1 
ATOM   1513 N  NZ  . LYS   A 1 237 ? 82.966  118.743 87.135  1.00 100.84 ? 237 LYS   A NZ  1 
ATOM   1514 N  N   . GLY   A 1 238 ? 83.401  112.239 91.223  1.00 107.88 ? 238 GLY   A N   1 
ATOM   1515 C  CA  . GLY   A 1 238 ? 83.381  110.794 91.340  1.00 107.88 ? 238 GLY   A CA  1 
ATOM   1516 C  C   . GLY   A 1 238 ? 84.052  110.254 92.585  1.00 107.88 ? 238 GLY   A C   1 
ATOM   1517 O  O   . GLY   A 1 238 ? 84.993  109.461 92.492  1.00 107.88 ? 238 GLY   A O   1 
ATOM   1518 N  N   . VAL   A 1 239 ? 83.590  110.688 93.758  1.00 108.75 ? 239 VAL   A N   1 
ATOM   1519 C  CA  . VAL   A 1 239 ? 84.139  110.162 95.004  1.00 108.75 ? 239 VAL   A CA  1 
ATOM   1520 C  C   . VAL   A 1 239 ? 83.847  108.670 95.127  1.00 108.75 ? 239 VAL   A C   1 
ATOM   1521 O  O   . VAL   A 1 239 ? 84.647  107.910 95.686  1.00 108.75 ? 239 VAL   A O   1 
ATOM   1522 C  CB  . VAL   A 1 239 ? 83.601  110.962 96.207  1.00 108.75 ? 239 VAL   A CB  1 
ATOM   1523 C  CG1 . VAL   A 1 239 ? 82.089  110.817 96.331  1.00 108.75 ? 239 VAL   A CG1 1 
ATOM   1524 C  CG2 . VAL   A 1 239 ? 84.293  110.531 97.492  1.00 108.75 ? 239 VAL   A CG2 1 
ATOM   1525 N  N   . ARG   A 1 240 ? 82.705  108.223 94.596  1.00 116.17 ? 240 ARG   A N   1 
ATOM   1526 C  CA  . ARG   A 1 240 ? 82.361  106.807 94.643  1.00 116.17 ? 240 ARG   A CA  1 
ATOM   1527 C  C   . ARG   A 1 240 ? 83.148  105.984 93.632  1.00 116.17 ? 240 ARG   A C   1 
ATOM   1528 O  O   . ARG   A 1 240 ? 83.112  104.751 93.695  1.00 116.17 ? 240 ARG   A O   1 
ATOM   1529 C  CB  . ARG   A 1 240 ? 80.858  106.619 94.415  1.00 116.17 ? 240 ARG   A CB  1 
ATOM   1530 C  CG  . ARG   A 1 240 ? 80.430  106.493 92.952  1.00 116.17 ? 240 ARG   A CG  1 
ATOM   1531 C  CD  . ARG   A 1 240 ? 80.665  107.777 92.164  1.00 116.17 ? 240 ARG   A CD  1 
ATOM   1532 N  NE  . ARG   A 1 240 ? 80.106  107.712 90.819  1.00 116.17 ? 240 ARG   A NE  1 
ATOM   1533 C  CZ  . ARG   A 1 240 ? 80.676  107.088 89.797  1.00 116.17 ? 240 ARG   A CZ  1 
ATOM   1534 N  NH1 . ARG   A 1 240 ? 81.832  106.458 89.928  1.00 116.17 ? 240 ARG   A NH1 1 
ATOM   1535 N  NH2 . ARG   A 1 240 ? 80.071  107.096 88.612  1.00 116.17 ? 240 ARG   A NH2 1 
ATOM   1536 N  N   . SER   A 1 241 ? 83.870  106.633 92.715  1.00 116.00 ? 241 SER   A N   1 
ATOM   1537 C  CA  . SER   A 1 241 ? 84.584  105.916 91.663  1.00 116.00 ? 241 SER   A CA  1 
ATOM   1538 C  C   . SER   A 1 241 ? 85.731  105.070 92.196  1.00 116.00 ? 241 SER   A C   1 
ATOM   1539 O  O   . SER   A 1 241 ? 86.284  104.264 91.440  1.00 116.00 ? 241 SER   A O   1 
ATOM   1540 C  CB  . SER   A 1 241 ? 85.116  106.901 90.620  1.00 116.00 ? 241 SER   A CB  1 
ATOM   1541 O  OG  . SER   A 1 241 ? 85.914  106.238 89.655  1.00 116.00 ? 241 SER   A OG  1 
ATOM   1542 N  N   . THR   A 1 242 ? 86.106  105.235 93.467  1.00 111.49 ? 242 THR   A N   1 
ATOM   1543 C  CA  . THR   A 1 242 ? 87.162  104.407 94.040  1.00 111.49 ? 242 THR   A CA  1 
ATOM   1544 C  C   . THR   A 1 242 ? 86.779  102.931 94.056  1.00 111.49 ? 242 THR   A C   1 
ATOM   1545 O  O   . THR   A 1 242 ? 87.658  102.065 94.124  1.00 111.49 ? 242 THR   A O   1 
ATOM   1546 C  CB  . THR   A 1 242 ? 87.497  104.887 95.454  1.00 111.49 ? 242 THR   A CB  1 
ATOM   1547 O  OG1 . THR   A 1 242 ? 88.643  104.181 95.944  1.00 111.49 ? 242 THR   A OG1 1 
ATOM   1548 C  CG2 . THR   A 1 242 ? 86.321  104.665 96.394  1.00 111.49 ? 242 THR   A CG2 1 
ATOM   1549 N  N   . GLY   A 1 243 ? 85.485  102.623 93.999  1.00 119.30 ? 243 GLY   A N   1 
ATOM   1550 C  CA  . GLY   A 1 243 ? 85.047  101.242 93.974  1.00 119.30 ? 243 GLY   A CA  1 
ATOM   1551 C  C   . GLY   A 1 243 ? 83.813  100.986 93.133  1.00 119.30 ? 243 GLY   A C   1 
ATOM   1552 O  O   . GLY   A 1 243 ? 83.243  99.893  93.185  1.00 119.30 ? 243 GLY   A O   1 
ATOM   1553 N  N   . LYS   A 1 244 ? 83.393  101.974 92.345  1.00 122.63 ? 244 LYS   A N   1 
ATOM   1554 C  CA  . LYS   A 1 244 ? 82.149  101.857 91.591  1.00 122.63 ? 244 LYS   A CA  1 
ATOM   1555 C  C   . LYS   A 1 244 ? 82.381  101.309 90.187  1.00 122.63 ? 244 LYS   A C   1 
ATOM   1556 O  O   . LYS   A 1 244 ? 81.793  100.291 89.811  1.00 122.63 ? 244 LYS   A O   1 
ATOM   1557 C  CB  . LYS   A 1 244 ? 81.446  103.214 91.513  1.00 122.63 ? 244 LYS   A CB  1 
ATOM   1558 C  CG  . LYS   A 1 244 ? 80.165  103.207 90.699  1.00 122.63 ? 244 LYS   A CG  1 
ATOM   1559 C  CD  . LYS   A 1 244 ? 79.090  102.361 91.363  1.00 122.63 ? 244 LYS   A CD  1 
ATOM   1560 C  CE  . LYS   A 1 244 ? 77.767  102.480 90.626  1.00 122.63 ? 244 LYS   A CE  1 
ATOM   1561 N  NZ  . LYS   A 1 244 ? 77.848  101.898 89.257  1.00 122.63 ? 244 LYS   A NZ  1 
ATOM   1562 N  N   . VAL   A 1 245 ? 83.229  101.980 89.403  1.00 123.69 ? 245 VAL   A N   1 
ATOM   1563 C  CA  . VAL   A 1 245 ? 83.448  101.573 88.021  1.00 123.69 ? 245 VAL   A CA  1 
ATOM   1564 C  C   . VAL   A 1 245 ? 84.653  100.657 87.878  1.00 123.69 ? 245 VAL   A C   1 
ATOM   1565 O  O   . VAL   A 1 245 ? 84.925  100.161 86.780  1.00 123.69 ? 245 VAL   A O   1 
ATOM   1566 C  CB  . VAL   A 1 245 ? 83.603  102.813 87.118  1.00 123.69 ? 245 VAL   A CB  1 
ATOM   1567 C  CG1 . VAL   A 1 245 ? 82.255  103.473 86.884  1.00 123.69 ? 245 VAL   A CG1 1 
ATOM   1568 C  CG2 . VAL   A 1 245 ? 84.584  103.799 87.735  1.00 123.69 ? 245 VAL   A CG2 1 
ATOM   1569 N  N   . VAL   A 1 246 ? 85.387  100.417 88.962  1.00 121.30 ? 246 VAL   A N   1 
ATOM   1570 C  CA  . VAL   A 1 246 ? 86.674  99.733  88.890  1.00 121.30 ? 246 VAL   A CA  1 
ATOM   1571 C  C   . VAL   A 1 246 ? 86.514  98.216  88.900  1.00 121.30 ? 246 VAL   A C   1 
ATOM   1572 O  O   . VAL   A 1 246 ? 87.506  97.486  89.012  1.00 121.30 ? 246 VAL   A O   1 
ATOM   1573 C  CB  . VAL   A 1 246 ? 87.597  100.187 90.035  1.00 121.30 ? 246 VAL   A CB  1 
ATOM   1574 C  CG1 . VAL   A 1 246 ? 87.777  101.697 90.004  1.00 121.30 ? 246 VAL   A CG1 1 
ATOM   1575 C  CG2 . VAL   A 1 246 ? 87.042  99.736  91.374  1.00 121.30 ? 246 VAL   A CG2 1 
ATOM   1576 N  N   . TYR   A 1 247 ? 85.277  97.724  88.796  1.00 121.29 ? 247 TYR   A N   1 
ATOM   1577 C  CA  . TYR   A 1 247 ? 85.044  96.286  88.917  1.00 121.29 ? 247 TYR   A CA  1 
ATOM   1578 C  C   . TYR   A 1 247 ? 85.767  95.508  87.821  1.00 121.29 ? 247 TYR   A C   1 
ATOM   1579 O  O   . TYR   A 1 247 ? 86.307  94.423  88.065  1.00 121.29 ? 247 TYR   A O   1 
ATOM   1580 C  CB  . TYR   A 1 247 ? 83.540  95.975  88.912  1.00 121.29 ? 247 TYR   A CB  1 
ATOM   1581 C  CG  . TYR   A 1 247 ? 82.704  96.717  87.888  1.00 121.29 ? 247 TYR   A CG  1 
ATOM   1582 C  CD1 . TYR   A 1 247 ? 81.811  97.702  88.281  1.00 121.29 ? 247 TYR   A CD1 1 
ATOM   1583 C  CD2 . TYR   A 1 247 ? 82.779  96.407  86.537  1.00 121.29 ? 247 TYR   A CD2 1 
ATOM   1584 C  CE1 . TYR   A 1 247 ? 81.035  98.377  87.357  1.00 121.29 ? 247 TYR   A CE1 1 
ATOM   1585 C  CE2 . TYR   A 1 247 ? 82.009  97.075  85.604  1.00 121.29 ? 247 TYR   A CE2 1 
ATOM   1586 C  CZ  . TYR   A 1 247 ? 81.138  98.059  86.020  1.00 121.29 ? 247 TYR   A CZ  1 
ATOM   1587 O  OH  . TYR   A 1 247 ? 80.369  98.725  85.094  1.00 121.29 ? 247 TYR   A OH  1 
ATOM   1588 N  N   . PHE   A 1 248 ? 85.791  96.048  86.600  1.00 120.95 ? 248 PHE   A N   1 
ATOM   1589 C  CA  . PHE   A 1 248 ? 86.427  95.327  85.501  1.00 120.95 ? 248 PHE   A CA  1 
ATOM   1590 C  C   . PHE   A 1 248 ? 87.922  95.617  85.434  1.00 120.95 ? 248 PHE   A C   1 
ATOM   1591 O  O   . PHE   A 1 248 ? 88.698  94.784  84.952  1.00 120.95 ? 248 PHE   A O   1 
ATOM   1592 C  CB  . PHE   A 1 248 ? 85.740  95.664  84.175  1.00 120.95 ? 248 PHE   A CB  1 
ATOM   1593 C  CG  . PHE   A 1 248 ? 85.865  97.105  83.764  1.00 120.95 ? 248 PHE   A CG  1 
ATOM   1594 C  CD1 . PHE   A 1 248 ? 84.937  98.041  84.185  1.00 120.95 ? 248 PHE   A CD1 1 
ATOM   1595 C  CD2 . PHE   A 1 248 ? 86.890  97.516  82.928  1.00 120.95 ? 248 PHE   A CD2 1 
ATOM   1596 C  CE1 . PHE   A 1 248 ? 85.041  99.364  83.800  1.00 120.95 ? 248 PHE   A CE1 1 
ATOM   1597 C  CE2 . PHE   A 1 248 ? 86.997  98.838  82.537  1.00 120.95 ? 248 PHE   A CE2 1 
ATOM   1598 C  CZ  . PHE   A 1 248 ? 86.073  99.763  82.976  1.00 120.95 ? 248 PHE   A CZ  1 
ATOM   1599 N  N   . THR   A 1 249 ? 88.349  96.791  85.907  1.00 115.64 ? 249 THR   A N   1 
ATOM   1600 C  CA  . THR   A 1 249 ? 89.775  97.095  85.928  1.00 115.64 ? 249 THR   A CA  1 
ATOM   1601 C  C   . THR   A 1 249 ? 90.494  96.417  87.085  1.00 115.64 ? 249 THR   A C   1 
ATOM   1602 O  O   . THR   A 1 249 ? 91.727  96.365  87.082  1.00 115.64 ? 249 THR   A O   1 
ATOM   1603 C  CB  . THR   A 1 249 ? 90.012  98.605  86.004  1.00 115.64 ? 249 THR   A CB  1 
ATOM   1604 O  OG1 . THR   A 1 249 ? 89.233  99.164  87.068  1.00 115.64 ? 249 THR   A OG1 1 
ATOM   1605 C  CG2 . THR   A 1 249 ? 89.645  99.277  84.692  1.00 115.64 ? 249 THR   A CG2 1 
ATOM   1606 N  N   . ALA   A 1 250 ? 89.759  95.910  88.078  1.00 109.56 ? 250 ALA   A N   1 
ATOM   1607 C  CA  . ALA   A 1 250 ? 90.400  95.240  89.204  1.00 109.56 ? 250 ALA   A CA  1 
ATOM   1608 C  C   . ALA   A 1 250 ? 91.111  93.957  88.795  1.00 109.56 ? 250 ALA   A C   1 
ATOM   1609 O  O   . ALA   A 1 250 ? 92.116  93.594  89.416  1.00 109.56 ? 250 ALA   A O   1 
ATOM   1610 C  CB  . ALA   A 1 250 ? 89.370  94.937  90.292  1.00 109.56 ? 250 ALA   A CB  1 
ATOM   1611 N  N   . THR   A 1 251 ? 90.614  93.259  87.773  1.00 105.45 ? 251 THR   A N   1 
ATOM   1612 C  CA  . THR   A 1 251 ? 91.256  92.024  87.337  1.00 105.45 ? 251 THR   A CA  1 
ATOM   1613 C  C   . THR   A 1 251 ? 92.474  92.285  86.459  1.00 105.45 ? 251 THR   A C   1 
ATOM   1614 O  O   . THR   A 1 251 ? 93.283  91.374  86.246  1.00 105.45 ? 251 THR   A O   1 
ATOM   1615 C  CB  . THR   A 1 251 ? 90.254  91.145  86.588  1.00 105.45 ? 251 THR   A CB  1 
ATOM   1616 O  OG1 . THR   A 1 251 ? 89.778  91.839  85.428  1.00 105.45 ? 251 THR   A OG1 1 
ATOM   1617 C  CG2 . THR   A 1 251 ? 89.076  90.800  87.484  1.00 105.45 ? 251 THR   A CG2 1 
ATOM   1618 N  N   . PHE   A 1 252 ? 92.617  93.503  85.937  1.00 99.65  ? 252 PHE   A N   1 
ATOM   1619 C  CA  . PHE   A 1 252 ? 93.749  93.808  85.064  1.00 99.65  ? 252 PHE   A CA  1 
ATOM   1620 C  C   . PHE   A 1 252 ? 95.096  93.689  85.772  1.00 99.65  ? 252 PHE   A C   1 
ATOM   1621 O  O   . PHE   A 1 252 ? 96.002  93.044  85.213  1.00 99.65  ? 252 PHE   A O   1 
ATOM   1622 C  CB  . PHE   A 1 252 ? 93.558  95.197  84.445  1.00 99.65  ? 252 PHE   A CB  1 
ATOM   1623 C  CG  . PHE   A 1 252 ? 94.283  95.390  83.141  1.00 99.65  ? 252 PHE   A CG  1 
ATOM   1624 C  CD1 . PHE   A 1 252 ? 93.578  95.508  81.956  1.00 99.65  ? 252 PHE   A CD1 1 
ATOM   1625 C  CD2 . PHE   A 1 252 ? 95.667  95.453  83.100  1.00 99.65  ? 252 PHE   A CD2 1 
ATOM   1626 C  CE1 . PHE   A 1 252 ? 94.238  95.685  80.754  1.00 99.65  ? 252 PHE   A CE1 1 
ATOM   1627 C  CE2 . PHE   A 1 252 ? 96.333  95.628  81.902  1.00 99.65  ? 252 PHE   A CE2 1 
ATOM   1628 C  CZ  . PHE   A 1 252 ? 95.617  95.745  80.728  1.00 99.65  ? 252 PHE   A CZ  1 
ATOM   1629 N  N   . PRO   A 1 253 ? 95.316  94.284  86.956  1.00 97.59  ? 253 PRO   A N   1 
ATOM   1630 C  CA  . PRO   A 1 253 ? 96.631  94.122  87.597  1.00 97.59  ? 253 PRO   A CA  1 
ATOM   1631 C  C   . PRO   A 1 253 ? 96.975  92.677  87.895  1.00 97.59  ? 253 PRO   A C   1 
ATOM   1632 O  O   . PRO   A 1 253 ? 98.138  92.286  87.762  1.00 97.59  ? 253 PRO   A O   1 
ATOM   1633 C  CB  . PRO   A 1 253 ? 96.500  94.952  88.882  1.00 97.59  ? 253 PRO   A CB  1 
ATOM   1634 C  CG  . PRO   A 1 253 ? 95.414  95.915  88.603  1.00 97.59  ? 253 PRO   A CG  1 
ATOM   1635 C  CD  . PRO   A 1 253 ? 94.444  95.159  87.757  1.00 97.59  ? 253 PRO   A CD  1 
ATOM   1636 N  N   . PHE   A 1 254 ? 95.990  91.865  88.285  1.00 95.10  ? 254 PHE   A N   1 
ATOM   1637 C  CA  . PHE   A 1 254 ? 96.270  90.462  88.570  1.00 95.10  ? 254 PHE   A CA  1 
ATOM   1638 C  C   . PHE   A 1 254 ? 96.654  89.703  87.306  1.00 95.10  ? 254 PHE   A C   1 
ATOM   1639 O  O   . PHE   A 1 254 ? 97.569  88.874  87.331  1.00 95.10  ? 254 PHE   A O   1 
ATOM   1640 C  CB  . PHE   A 1 254 ? 95.067  89.814  89.252  1.00 95.10  ? 254 PHE   A CB  1 
ATOM   1641 C  CG  . PHE   A 1 254 ? 95.178  89.769  90.748  1.00 95.10  ? 254 PHE   A CG  1 
ATOM   1642 C  CD1 . PHE   A 1 254 ? 94.517  90.698  91.533  1.00 95.10  ? 254 PHE   A CD1 1 
ATOM   1643 C  CD2 . PHE   A 1 254 ? 95.954  88.805  91.368  1.00 95.10  ? 254 PHE   A CD2 1 
ATOM   1644 C  CE1 . PHE   A 1 254 ? 94.620  90.662  92.909  1.00 95.10  ? 254 PHE   A CE1 1 
ATOM   1645 C  CE2 . PHE   A 1 254 ? 96.062  88.763  92.744  1.00 95.10  ? 254 PHE   A CE2 1 
ATOM   1646 C  CZ  . PHE   A 1 254 ? 95.394  89.693  93.516  1.00 95.10  ? 254 PHE   A CZ  1 
ATOM   1647 N  N   . ALA   A 1 255 ? 95.973  89.977  86.191  1.00 90.67  ? 255 ALA   A N   1 
ATOM   1648 C  CA  . ALA   A 1 255 ? 96.331  89.333  84.931  1.00 90.67  ? 255 ALA   A CA  1 
ATOM   1649 C  C   . ALA   A 1 255 ? 97.729  89.743  84.483  1.00 90.67  ? 255 ALA   A C   1 
ATOM   1650 O  O   . ALA   A 1 255 ? 98.527  88.906  84.039  1.00 90.67  ? 255 ALA   A O   1 
ATOM   1651 C  CB  . ALA   A 1 255 ? 95.297  89.672  83.858  1.00 90.67  ? 255 ALA   A CB  1 
ATOM   1652 N  N   . MET   A 1 256 ? 98.047  91.035  84.599  1.00 90.42  ? 256 MET   A N   1 
ATOM   1653 C  CA  . MET   A 1 256 ? 99.379  91.497  84.224  1.00 90.42  ? 256 MET   A CA  1 
ATOM   1654 C  C   . MET   A 1 256 ? 100.448 90.886  85.122  1.00 90.42  ? 256 MET   A C   1 
ATOM   1655 O  O   . MET   A 1 256 ? 101.521 90.498  84.644  1.00 90.42  ? 256 MET   A O   1 
ATOM   1656 C  CB  . MET   A 1 256 ? 99.440  93.023  84.271  1.00 90.42  ? 256 MET   A CB  1 
ATOM   1657 C  CG  . MET   A 1 256 ? 100.618 93.616  83.515  1.00 90.42  ? 256 MET   A CG  1 
ATOM   1658 S  SD  . MET   A 1 256 ? 100.563 93.256  81.750  1.00 90.42  ? 256 MET   A SD  1 
ATOM   1659 C  CE  . MET   A 1 256 ? 102.310 93.246  81.351  1.00 90.42  ? 256 MET   A CE  1 
ATOM   1660 N  N   . LEU   A 1 257 ? 100.172 90.787  86.425  1.00 89.74  ? 257 LEU   A N   1 
ATOM   1661 C  CA  . LEU   A 1 257 ? 101.116 90.159  87.341  1.00 89.74  ? 257 LEU   A CA  1 
ATOM   1662 C  C   . LEU   A 1 257 ? 101.291 88.681  87.033  1.00 89.74  ? 257 LEU   A C   1 
ATOM   1663 O  O   . LEU   A 1 257 ? 102.396 88.151  87.164  1.00 89.74  ? 257 LEU   A O   1 
ATOM   1664 C  CB  . LEU   A 1 257 ? 100.656 90.354  88.785  1.00 89.74  ? 257 LEU   A CB  1 
ATOM   1665 C  CG  . LEU   A 1 257 ? 101.325 91.497  89.552  1.00 89.74  ? 257 LEU   A CG  1 
ATOM   1666 C  CD1 . LEU   A 1 257 ? 100.668 91.697  90.909  1.00 89.74  ? 257 LEU   A CD1 1 
ATOM   1667 C  CD2 . LEU   A 1 257 ? 102.815 91.237  89.706  1.00 89.74  ? 257 LEU   A CD2 1 
ATOM   1668 N  N   . LEU   A 1 258 ? 100.218 87.998  86.630  1.00 86.66  ? 258 LEU   A N   1 
ATOM   1669 C  CA  . LEU   A 1 258 ? 100.338 86.600  86.228  1.00 86.66  ? 258 LEU   A CA  1 
ATOM   1670 C  C   . LEU   A 1 258 ? 101.213 86.459  84.988  1.00 86.66  ? 258 LEU   A C   1 
ATOM   1671 O  O   . LEU   A 1 258 ? 102.053 85.553  84.913  1.00 86.66  ? 258 LEU   A O   1 
ATOM   1672 C  CB  . LEU   A 1 258 ? 98.948  86.008  85.986  1.00 86.66  ? 258 LEU   A CB  1 
ATOM   1673 C  CG  . LEU   A 1 258 ? 98.818  84.491  85.837  1.00 86.66  ? 258 LEU   A CG  1 
ATOM   1674 C  CD1 . LEU   A 1 258 ? 97.499  84.022  86.427  1.00 86.66  ? 258 LEU   A CD1 1 
ATOM   1675 C  CD2 . LEU   A 1 258 ? 98.924  84.066  84.380  1.00 86.66  ? 258 LEU   A CD2 1 
ATOM   1676 N  N   . VAL   A 1 259 ? 101.031 87.346  84.006  1.00 85.90  ? 259 VAL   A N   1 
ATOM   1677 C  CA  . VAL   A 1 259 ? 101.871 87.306  82.810  1.00 85.90  ? 259 VAL   A CA  1 
ATOM   1678 C  C   . VAL   A 1 259 ? 103.330 87.552  83.176  1.00 85.90  ? 259 VAL   A C   1 
ATOM   1679 O  O   . VAL   A 1 259 ? 104.237 86.869  82.680  1.00 85.90  ? 259 VAL   A O   1 
ATOM   1680 C  CB  . VAL   A 1 259 ? 101.370 88.320  81.765  1.00 85.90  ? 259 VAL   A CB  1 
ATOM   1681 C  CG1 . VAL   A 1 259 ? 102.291 88.332  80.557  1.00 85.90  ? 259 VAL   A CG1 1 
ATOM   1682 C  CG2 . VAL   A 1 259 ? 99.951  87.986  81.343  1.00 85.90  ? 259 VAL   A CG2 1 
ATOM   1683 N  N   . LEU   A 1 260 ? 103.576 88.530  84.051  1.00 86.01  ? 260 LEU   A N   1 
ATOM   1684 C  CA  . LEU   A 1 260 ? 104.938 88.810  84.494  1.00 86.01  ? 260 LEU   A CA  1 
ATOM   1685 C  C   . LEU   A 1 260 ? 105.536 87.622  85.235  1.00 86.01  ? 260 LEU   A C   1 
ATOM   1686 O  O   . LEU   A 1 260 ? 106.717 87.305  85.064  1.00 86.01  ? 260 LEU   A O   1 
ATOM   1687 C  CB  . LEU   A 1 260 ? 104.952 90.050  85.383  1.00 86.01  ? 260 LEU   A CB  1 
ATOM   1688 C  CG  . LEU   A 1 260 ? 104.583 91.370  84.714  1.00 86.01  ? 260 LEU   A CG  1 
ATOM   1689 C  CD1 . LEU   A 1 260 ? 104.506 92.460  85.757  1.00 86.01  ? 260 LEU   A CD1 1 
ATOM   1690 C  CD2 . LEU   A 1 260 ? 105.593 91.724  83.636  1.00 86.01  ? 260 LEU   A CD2 1 
ATOM   1691 N  N   . LEU   A 1 261 ? 104.737 86.964  86.077  1.00 85.51  ? 261 LEU   A N   1 
ATOM   1692 C  CA  . LEU   A 1 261 ? 105.215 85.799  86.811  1.00 85.51  ? 261 LEU   A CA  1 
ATOM   1693 C  C   . LEU   A 1 261 ? 105.597 84.677  85.856  1.00 85.51  ? 261 LEU   A C   1 
ATOM   1694 O  O   . LEU   A 1 261 ? 106.647 84.044  86.012  1.00 85.51  ? 261 LEU   A O   1 
ATOM   1695 C  CB  . LEU   A 1 261 ? 104.141 85.334  87.797  1.00 85.51  ? 261 LEU   A CB  1 
ATOM   1696 C  CG  . LEU   A 1 261 ? 104.528 84.370  88.922  1.00 85.51  ? 261 LEU   A CG  1 
ATOM   1697 C  CD1 . LEU   A 1 261 ? 103.647 84.613  90.136  1.00 85.51  ? 261 LEU   A CD1 1 
ATOM   1698 C  CD2 . LEU   A 1 261 ? 104.420 82.920  88.476  1.00 85.51  ? 261 LEU   A CD2 1 
ATOM   1699 N  N   . VAL   A 1 262 ? 104.753 84.420  84.854  1.00 81.99  ? 262 VAL   A N   1 
ATOM   1700 C  CA  . VAL   A 1 262 ? 105.055 83.370  83.886  1.00 81.99  ? 262 VAL   A CA  1 
ATOM   1701 C  C   . VAL   A 1 262 ? 106.325 83.704  83.114  1.00 81.99  ? 262 VAL   A C   1 
ATOM   1702 O  O   . VAL   A 1 262 ? 107.200 82.847  82.929  1.00 81.99  ? 262 VAL   A O   1 
ATOM   1703 C  CB  . VAL   A 1 262 ? 103.859 83.149  82.943  1.00 81.99  ? 262 VAL   A CB  1 
ATOM   1704 C  CG1 . VAL   A 1 262 ? 104.218 82.146  81.860  1.00 81.99  ? 262 VAL   A CG1 1 
ATOM   1705 C  CG2 . VAL   A 1 262 ? 102.651 82.667  83.727  1.00 81.99  ? 262 VAL   A CG2 1 
ATOM   1706 N  N   . ARG   A 1 263 ? 106.457 84.956  82.666  1.00 83.97  ? 263 ARG   A N   1 
ATOM   1707 C  CA  . ARG   A 1 263 ? 107.647 85.356  81.923  1.00 83.97  ? 263 ARG   A CA  1 
ATOM   1708 C  C   . ARG   A 1 263 ? 108.914 85.280  82.766  1.00 83.97  ? 263 ARG   A C   1 
ATOM   1709 O  O   . ARG   A 1 263 ? 109.956 84.856  82.255  1.00 83.97  ? 263 ARG   A O   1 
ATOM   1710 C  CB  . ARG   A 1 263 ? 107.470 86.769  81.368  1.00 83.97  ? 263 ARG   A CB  1 
ATOM   1711 C  CG  . ARG   A 1 263 ? 108.448 87.123  80.261  1.00 83.97  ? 263 ARG   A CG  1 
ATOM   1712 C  CD  . ARG   A 1 263 ? 108.553 86.002  79.238  1.00 83.97  ? 263 ARG   A CD  1 
ATOM   1713 N  NE  . ARG   A 1 263 ? 107.318 85.827  78.483  1.00 83.97  ? 263 ARG   A NE  1 
ATOM   1714 C  CZ  . ARG   A 1 263 ? 107.170 84.978  77.475  1.00 83.97  ? 263 ARG   A CZ  1 
ATOM   1715 N  NH1 . ARG   A 1 263 ? 108.167 84.210  77.065  1.00 83.97  ? 263 ARG   A NH1 1 
ATOM   1716 N  NH2 . ARG   A 1 263 ? 105.992 84.896  76.862  1.00 83.97  ? 263 ARG   A NH2 1 
ATOM   1717 N  N   . GLY   A 1 264 ? 108.853 85.682  84.034  1.00 82.66  ? 264 GLY   A N   1 
ATOM   1718 C  CA  . GLY   A 1 264 ? 109.998 85.594  84.917  1.00 82.66  ? 264 GLY   A CA  1 
ATOM   1719 C  C   . GLY   A 1 264 ? 110.394 84.168  85.236  1.00 82.66  ? 264 GLY   A C   1 
ATOM   1720 O  O   . GLY   A 1 264 ? 111.584 83.840  85.259  1.00 82.66  ? 264 GLY   A O   1 
ATOM   1721 N  N   . LEU   A 1 265 ? 109.403 83.309  85.488  1.00 86.07  ? 265 LEU   A N   1 
ATOM   1722 C  CA  . LEU   A 1 265 ? 109.694 81.902  85.740  1.00 86.07  ? 265 LEU   A CA  1 
ATOM   1723 C  C   . LEU   A 1 265 ? 110.312 81.244  84.514  1.00 86.07  ? 265 LEU   A C   1 
ATOM   1724 O  O   . LEU   A 1 265 ? 111.240 80.436  84.635  1.00 86.07  ? 265 LEU   A O   1 
ATOM   1725 C  CB  . LEU   A 1 265 ? 108.420 81.170  86.162  1.00 86.07  ? 265 LEU   A CB  1 
ATOM   1726 C  CG  . LEU   A 1 265 ? 108.196 80.982  87.665  1.00 86.07  ? 265 LEU   A CG  1 
ATOM   1727 C  CD1 . LEU   A 1 265 ? 108.046 82.321  88.369  1.00 86.07  ? 265 LEU   A CD1 1 
ATOM   1728 C  CD2 . LEU   A 1 265 ? 106.978 80.109  87.912  1.00 86.07  ? 265 LEU   A CD2 1 
ATOM   1729 N  N   . THR   A 1 266 ? 109.810 81.579  83.323  1.00 85.65  ? 266 THR   A N   1 
ATOM   1730 C  CA  . THR   A 1 266 ? 110.413 81.078  82.094  1.00 85.65  ? 266 THR   A CA  1 
ATOM   1731 C  C   . THR   A 1 266 ? 111.817 81.637  81.881  1.00 85.65  ? 266 THR   A C   1 
ATOM   1732 O  O   . THR   A 1 266 ? 112.649 80.976  81.250  1.00 85.65  ? 266 THR   A O   1 
ATOM   1733 C  CB  . THR   A 1 266 ? 109.509 81.420  80.905  1.00 85.65  ? 266 THR   A CB  1 
ATOM   1734 O  OG1 . THR   A 1 266 ? 108.226 80.812  81.093  1.00 85.65  ? 266 THR   A OG1 1 
ATOM   1735 C  CG2 . THR   A 1 266 ? 110.102 80.911  79.599  1.00 85.65  ? 266 THR   A CG2 1 
ATOM   1736 N  N   . LEU   A 1 267 ? 112.102 82.819  82.421  1.00 87.13  ? 267 LEU   A N   1 
ATOM   1737 C  CA  . LEU   A 1 267 ? 113.399 83.449  82.226  1.00 87.13  ? 267 LEU   A CA  1 
ATOM   1738 C  C   . LEU   A 1 267 ? 114.498 82.621  82.892  1.00 87.13  ? 267 LEU   A C   1 
ATOM   1739 O  O   . LEU   A 1 267 ? 114.334 82.174  84.032  1.00 87.13  ? 267 LEU   A O   1 
ATOM   1740 C  CB  . LEU   A 1 267 ? 113.381 84.866  82.800  1.00 87.13  ? 267 LEU   A CB  1 
ATOM   1741 C  CG  . LEU   A 1 267 ? 114.492 85.849  82.434  1.00 87.13  ? 267 LEU   A CG  1 
ATOM   1742 C  CD1 . LEU   A 1 267 ? 114.494 86.129  80.940  1.00 87.13  ? 267 LEU   A CD1 1 
ATOM   1743 C  CD2 . LEU   A 1 267 ? 114.306 87.138  83.214  1.00 87.13  ? 267 LEU   A CD2 1 
ATOM   1744 N  N   . PRO   A 1 268 ? 115.621 82.401  82.213  1.00 87.69  ? 268 PRO   A N   1 
ATOM   1745 C  CA  . PRO   A 1 268 ? 116.676 81.555  82.780  1.00 87.69  ? 268 PRO   A CA  1 
ATOM   1746 C  C   . PRO   A 1 268 ? 117.367 82.217  83.962  1.00 87.69  ? 268 PRO   A C   1 
ATOM   1747 O  O   . PRO   A 1 268 ? 117.211 83.410  84.228  1.00 87.69  ? 268 PRO   A O   1 
ATOM   1748 C  CB  . PRO   A 1 268 ? 117.647 81.366  81.610  1.00 87.69  ? 268 PRO   A CB  1 
ATOM   1749 C  CG  . PRO   A 1 268 ? 117.432 82.568  80.759  1.00 87.69  ? 268 PRO   A CG  1 
ATOM   1750 C  CD  . PRO   A 1 268 ? 115.965 82.876  80.862  1.00 87.69  ? 268 PRO   A CD  1 
ATOM   1751 N  N   . GLY   A 1 269 ? 118.148 81.410  84.672  1.00 82.25  ? 269 GLY   A N   1 
ATOM   1752 C  CA  . GLY   A 1 269 ? 118.861 81.883  85.847  1.00 82.25  ? 269 GLY   A CA  1 
ATOM   1753 C  C   . GLY   A 1 269 ? 117.964 82.268  87.002  1.00 82.25  ? 269 GLY   A C   1 
ATOM   1754 O  O   . GLY   A 1 269 ? 118.198 83.297  87.647  1.00 82.25  ? 269 GLY   A O   1 
ATOM   1755 N  N   . ALA   A 1 270 ? 116.937 81.466  87.281  1.00 81.03  ? 270 ALA   A N   1 
ATOM   1756 C  CA  . ALA   A 1 270 ? 116.010 81.744  88.367  1.00 81.03  ? 270 ALA   A CA  1 
ATOM   1757 C  C   . ALA   A 1 270 ? 116.254 80.895  89.606  1.00 81.03  ? 270 ALA   A C   1 
ATOM   1758 O  O   . ALA   A 1 270 ? 115.728 81.229  90.674  1.00 81.03  ? 270 ALA   A O   1 
ATOM   1759 C  CB  . ALA   A 1 270 ? 114.563 81.542  87.896  1.00 81.03  ? 270 ALA   A CB  1 
ATOM   1760 N  N   . GLY   A 1 271 ? 117.026 79.813  89.496  1.00 80.64  ? 271 GLY   A N   1 
ATOM   1761 C  CA  . GLY   A 1 271 ? 117.284 78.982  90.662  1.00 80.64  ? 271 GLY   A CA  1 
ATOM   1762 C  C   . GLY   A 1 271 ? 118.029 79.728  91.751  1.00 80.64  ? 271 GLY   A C   1 
ATOM   1763 O  O   . GLY   A 1 271 ? 117.709 79.610  92.937  1.00 80.64  ? 271 GLY   A O   1 
ATOM   1764 N  N   . ALA   A 1 272 ? 119.038 80.512  91.359  1.00 80.91  ? 272 ALA   A N   1 
ATOM   1765 C  CA  . ALA   A 1 272 ? 119.770 81.316  92.331  1.00 80.91  ? 272 ALA   A CA  1 
ATOM   1766 C  C   . ALA   A 1 272 ? 118.858 82.342  92.990  1.00 80.91  ? 272 ALA   A C   1 
ATOM   1767 O  O   . ALA   A 1 272 ? 118.949 82.577  94.201  1.00 80.91  ? 272 ALA   A O   1 
ATOM   1768 C  CB  . ALA   A 1 272 ? 120.957 82.003  91.658  1.00 80.91  ? 272 ALA   A CB  1 
ATOM   1769 N  N   . GLY   A 1 273 ? 117.975 82.965  92.208  1.00 80.44  ? 273 GLY   A N   1 
ATOM   1770 C  CA  . GLY   A 1 273 ? 117.036 83.914  92.783  1.00 80.44  ? 273 GLY   A CA  1 
ATOM   1771 C  C   . GLY   A 1 273 ? 116.090 83.269  93.777  1.00 80.44  ? 273 GLY   A C   1 
ATOM   1772 O  O   . GLY   A 1 273 ? 115.818 83.829  94.841  1.00 80.44  ? 273 GLY   A O   1 
ATOM   1773 N  N   . ILE   A 1 274 ? 115.584 82.079  93.448  1.00 79.64  ? 274 ILE   A N   1 
ATOM   1774 C  CA  . ILE   A 1 274 ? 114.691 81.368  94.361  1.00 79.64  ? 274 ILE   A CA  1 
ATOM   1775 C  C   . ILE   A 1 274 ? 115.428 80.991  95.641  1.00 79.64  ? 274 ILE   A C   1 
ATOM   1776 O  O   . ILE   A 1 274 ? 114.896 81.129  96.751  1.00 79.64  ? 274 ILE   A O   1 
ATOM   1777 C  CB  . ILE   A 1 274 ? 114.087 80.133  93.670  1.00 79.64  ? 274 ILE   A CB  1 
ATOM   1778 C  CG1 . ILE   A 1 274 ? 113.253 80.555  92.461  1.00 79.64  ? 274 ILE   A CG1 1 
ATOM   1779 C  CG2 . ILE   A 1 274 ? 113.237 79.337  94.643  1.00 79.64  ? 274 ILE   A CG2 1 
ATOM   1780 C  CD1 . ILE   A 1 274 ? 112.100 81.464  92.809  1.00 79.64  ? 274 ILE   A CD1 1 
ATOM   1781 N  N   . LYS   A 1 275 ? 116.665 80.507  95.507  1.00 84.26  ? 275 LYS   A N   1 
ATOM   1782 C  CA  . LYS   A 1 275 ? 117.449 80.137  96.682  1.00 84.26  ? 275 LYS   A CA  1 
ATOM   1783 C  C   . LYS   A 1 275 ? 117.716 81.348  97.568  1.00 84.26  ? 275 LYS   A C   1 
ATOM   1784 O  O   . LYS   A 1 275 ? 117.610 81.268  98.798  1.00 84.26  ? 275 LYS   A O   1 
ATOM   1785 C  CB  . LYS   A 1 275 ? 118.762 79.483  96.248  1.00 84.26  ? 275 LYS   A CB  1 
ATOM   1786 C  CG  . LYS   A 1 275 ? 119.888 79.614  97.261  1.00 84.26  ? 275 LYS   A CG  1 
ATOM   1787 C  CD  . LYS   A 1 275 ? 121.226 79.222  96.656  1.00 84.26  ? 275 LYS   A CD  1 
ATOM   1788 C  CE  . LYS   A 1 275 ? 122.308 79.139  97.718  1.00 84.26  ? 275 LYS   A CE  1 
ATOM   1789 N  NZ  . LYS   A 1 275 ? 123.387 78.187  97.338  1.00 84.26  ? 275 LYS   A NZ  1 
ATOM   1790 N  N   . PHE   A 1 276 ? 118.063 82.483  96.958  1.00 76.95  ? 276 PHE   A N   1 
ATOM   1791 C  CA  . PHE   A 1 276 ? 118.294 83.704  97.725  1.00 76.95  ? 276 PHE   A CA  1 
ATOM   1792 C  C   . PHE   A 1 276 ? 117.017 84.159  98.420  1.00 76.95  ? 276 PHE   A C   1 
ATOM   1793 O  O   . PHE   A 1 276 ? 117.046 84.606  99.572  1.00 76.95  ? 276 PHE   A O   1 
ATOM   1794 C  CB  . PHE   A 1 276 ? 118.838 84.796  96.800  1.00 76.95  ? 276 PHE   A CB  1 
ATOM   1795 C  CG  . PHE   A 1 276 ? 119.261 86.056  97.511  1.00 76.95  ? 276 PHE   A CG  1 
ATOM   1796 C  CD1 . PHE   A 1 276 ? 118.325 86.992  97.922  1.00 76.95  ? 276 PHE   A CD1 1 
ATOM   1797 C  CD2 . PHE   A 1 276 ? 120.600 86.307  97.757  1.00 76.95  ? 276 PHE   A CD2 1 
ATOM   1798 C  CE1 . PHE   A 1 276 ? 118.716 88.146  98.572  1.00 76.95  ? 276 PHE   A CE1 1 
ATOM   1799 C  CE2 . PHE   A 1 276 ? 120.997 87.460  98.405  1.00 76.95  ? 276 PHE   A CE2 1 
ATOM   1800 C  CZ  . PHE   A 1 276 ? 120.053 88.380  98.812  1.00 76.95  ? 276 PHE   A CZ  1 
ATOM   1801 N  N   . TYR   A 1 277 ? 115.882 84.058  97.727  1.00 76.50  ? 277 TYR   A N   1 
ATOM   1802 C  CA  . TYR   A 1 277 ? 114.621 84.524  98.291  1.00 76.50  ? 277 TYR   A CA  1 
ATOM   1803 C  C   . TYR   A 1 277 ? 114.171 83.651  99.456  1.00 76.50  ? 277 TYR   A C   1 
ATOM   1804 O  O   . TYR   A 1 277 ? 113.663 84.162  100.460 1.00 76.50  ? 277 TYR   A O   1 
ATOM   1805 C  CB  . TYR   A 1 277 ? 113.554 84.561  97.195  1.00 76.50  ? 277 TYR   A CB  1 
ATOM   1806 C  CG  . TYR   A 1 277 ? 112.188 85.030  97.645  1.00 76.50  ? 277 TYR   A CG  1 
ATOM   1807 C  CD1 . TYR   A 1 277 ? 112.050 86.063  98.560  1.00 76.50  ? 277 TYR   A CD1 1 
ATOM   1808 C  CD2 . TYR   A 1 277 ? 111.036 84.444  97.141  1.00 76.50  ? 277 TYR   A CD2 1 
ATOM   1809 C  CE1 . TYR   A 1 277 ? 110.801 86.492  98.966  1.00 76.50  ? 277 TYR   A CE1 1 
ATOM   1810 C  CE2 . TYR   A 1 277 ? 109.786 84.867  97.541  1.00 76.50  ? 277 TYR   A CE2 1 
ATOM   1811 C  CZ  . TYR   A 1 277 ? 109.673 85.890  98.453  1.00 76.50  ? 277 TYR   A CZ  1 
ATOM   1812 O  OH  . TYR   A 1 277 ? 108.427 86.314  98.853  1.00 76.50  ? 277 TYR   A OH  1 
ATOM   1813 N  N   . LEU   A 1 278 ? 114.358 82.334  99.350  1.00 82.65  ? 278 LEU   A N   1 
ATOM   1814 C  CA  . LEU   A 1 278 ? 113.748 81.397  100.305 1.00 82.65  ? 278 LEU   A CA  1 
ATOM   1815 C  C   . LEU   A 1 278 ? 114.682 81.038  101.459 1.00 82.65  ? 278 LEU   A C   1 
ATOM   1816 O  O   . LEU   A 1 278 ? 114.350 81.261  102.626 1.00 82.65  ? 278 LEU   A O   1 
ATOM   1817 C  CB  . LEU   A 1 278 ? 113.281 80.140  99.568  1.00 82.65  ? 278 LEU   A CB  1 
ATOM   1818 C  CG  . LEU   A 1 278 ? 112.111 80.329  98.602  1.00 82.65  ? 278 LEU   A CG  1 
ATOM   1819 C  CD1 . LEU   A 1 278 ? 111.697 78.999  97.995  1.00 82.65  ? 278 LEU   A CD1 1 
ATOM   1820 C  CD2 . LEU   A 1 278 ? 110.934 80.991  99.302  1.00 82.65  ? 278 LEU   A CD2 1 
ATOM   1821 N  N   . TYR   A 1 279 ? 115.845 80.475  101.145 1.00 91.79  ? 279 TYR   A N   1 
ATOM   1822 C  CA  . TYR   A 1 279 ? 116.704 79.908  102.175 1.00 91.79  ? 279 TYR   A CA  1 
ATOM   1823 C  C   . TYR   A 1 279 ? 117.220 81.004  103.107 1.00 91.79  ? 279 TYR   A C   1 
ATOM   1824 O  O   . TYR   A 1 279 ? 117.776 82.004  102.633 1.00 91.79  ? 279 TYR   A O   1 
ATOM   1825 C  CB  . TYR   A 1 279 ? 117.876 79.157  101.542 1.00 91.79  ? 279 TYR   A CB  1 
ATOM   1826 C  CG  . TYR   A 1 279 ? 117.493 77.810  100.972 1.00 91.79  ? 279 TYR   A CG  1 
ATOM   1827 C  CD1 . TYR   A 1 279 ? 116.270 77.228  101.280 1.00 91.79  ? 279 TYR   A CD1 1 
ATOM   1828 C  CD2 . TYR   A 1 279 ? 118.354 77.119  100.131 1.00 91.79  ? 279 TYR   A CD2 1 
ATOM   1829 C  CE1 . TYR   A 1 279 ? 115.914 75.998  100.764 1.00 91.79  ? 279 TYR   A CE1 1 
ATOM   1830 C  CE2 . TYR   A 1 279 ? 118.007 75.886  99.610  1.00 91.79  ? 279 TYR   A CE2 1 
ATOM   1831 C  CZ  . TYR   A 1 279 ? 116.786 75.331  99.930  1.00 91.79  ? 279 TYR   A CZ  1 
ATOM   1832 O  OH  . TYR   A 1 279 ? 116.434 74.105  99.415  1.00 91.79  ? 279 TYR   A OH  1 
ATOM   1833 N  N   . PRO   A 1 280 ? 117.075 80.847  104.419 1.00 92.56  ? 280 PRO   A N   1 
ATOM   1834 C  CA  . PRO   A 1 280 ? 117.446 81.907  105.356 1.00 92.56  ? 280 PRO   A CA  1 
ATOM   1835 C  C   . PRO   A 1 280 ? 118.936 81.910  105.683 1.00 92.56  ? 280 PRO   A C   1 
ATOM   1836 O  O   . PRO   A 1 280 ? 119.688 81.005  105.317 1.00 92.56  ? 280 PRO   A O   1 
ATOM   1837 C  CB  . PRO   A 1 280 ? 116.618 81.560  106.598 1.00 92.56  ? 280 PRO   A CB  1 
ATOM   1838 C  CG  . PRO   A 1 280 ? 116.549 80.070  106.569 1.00 92.56  ? 280 PRO   A CG  1 
ATOM   1839 C  CD  . PRO   A 1 280 ? 116.520 79.669  105.109 1.00 92.56  ? 280 PRO   A CD  1 
ATOM   1840 N  N   . ASP   A 1 281 ? 119.347 82.966  106.394 1.00 93.03  ? 281 ASP   A N   1 
ATOM   1841 C  CA  . ASP   A 1 281 ? 120.729 83.156  106.846 1.00 93.03  ? 281 ASP   A CA  1 
ATOM   1842 C  C   . ASP   A 1 281 ? 120.687 83.469  108.341 1.00 93.03  ? 281 ASP   A C   1 
ATOM   1843 O  O   . ASP   A 1 281 ? 120.563 84.628  108.745 1.00 93.03  ? 281 ASP   A O   1 
ATOM   1844 C  CB  . ASP   A 1 281 ? 121.423 84.262  106.048 1.00 93.03  ? 281 ASP   A CB  1 
ATOM   1845 C  CG  . ASP   A 1 281 ? 122.930 84.247  106.217 1.00 93.03  ? 281 ASP   A CG  1 
ATOM   1846 O  OD1 . ASP   A 1 281 ? 123.436 83.411  106.995 1.00 93.03  ? 281 ASP   A OD1 1 
ATOM   1847 O  OD2 . ASP   A 1 281 ? 123.610 85.072  105.572 1.00 93.03  ? 281 ASP   A OD2 1 
ATOM   1848 N  N   . ILE   A 1 282 ? 120.791 82.422  109.164 1.00 93.04  ? 282 ILE   A N   1 
ATOM   1849 C  CA  . ILE   A 1 282 ? 120.746 82.598  110.610 1.00 93.04  ? 282 ILE   A CA  1 
ATOM   1850 C  C   . ILE   A 1 282 ? 122.020 83.233  111.150 1.00 93.04  ? 282 ILE   A C   1 
ATOM   1851 O  O   . ILE   A 1 282 ? 122.067 83.611  112.326 1.00 93.04  ? 282 ILE   A O   1 
ATOM   1852 C  CB  . ILE   A 1 282 ? 120.488 81.251  111.307 1.00 93.04  ? 282 ILE   A CB  1 
ATOM   1853 C  CG1 . ILE   A 1 282 ? 121.690 80.322  111.125 1.00 93.04  ? 282 ILE   A CG1 1 
ATOM   1854 C  CG2 . ILE   A 1 282 ? 119.223 80.607  110.765 1.00 93.04  ? 282 ILE   A CG2 1 
ATOM   1855 C  CD1 . ILE   A 1 282 ? 121.835 79.287  112.218 1.00 93.04  ? 282 ILE   A CD1 1 
ATOM   1856 N  N   . THR   A 1 283 ? 123.060 83.355  110.322 1.00 91.84  ? 283 THR   A N   1 
ATOM   1857 C  CA  . THR   A 1 283 ? 124.341 83.864  110.801 1.00 91.84  ? 283 THR   A CA  1 
ATOM   1858 C  C   . THR   A 1 283 ? 124.248 85.318  111.249 1.00 91.84  ? 283 THR   A C   1 
ATOM   1859 O  O   . THR   A 1 283 ? 124.866 85.697  112.250 1.00 91.84  ? 283 THR   A O   1 
ATOM   1860 C  CB  . THR   A 1 283 ? 125.402 83.713  109.708 1.00 91.84  ? 283 THR   A CB  1 
ATOM   1861 O  OG1 . THR   A 1 283 ? 125.504 82.336  109.328 1.00 91.84  ? 283 THR   A OG1 1 
ATOM   1862 C  CG2 . THR   A 1 283 ? 126.757 84.197  110.203 1.00 91.84  ? 283 THR   A CG2 1 
ATOM   1863 N  N   . ARG   A 1 284 ? 123.481 86.142  110.535 1.00 87.93  ? 284 ARG   A N   1 
ATOM   1864 C  CA  . ARG   A 1 284 ? 123.445 87.580  110.777 1.00 87.93  ? 284 ARG   A CA  1 
ATOM   1865 C  C   . ARG   A 1 284 ? 122.091 88.038  111.310 1.00 87.93  ? 284 ARG   A C   1 
ATOM   1866 O  O   . ARG   A 1 284 ? 121.589 89.094  110.924 1.00 87.93  ? 284 ARG   A O   1 
ATOM   1867 C  CB  . ARG   A 1 284 ? 123.809 88.340  109.502 1.00 87.93  ? 284 ARG   A CB  1 
ATOM   1868 C  CG  . ARG   A 1 284 ? 122.962 87.980  108.293 1.00 87.93  ? 284 ARG   A CG  1 
ATOM   1869 C  CD  . ARG   A 1 284 ? 122.461 89.229  107.589 1.00 87.93  ? 284 ARG   A CD  1 
ATOM   1870 N  NE  . ARG   A 1 284 ? 121.668 90.081  108.468 1.00 87.93  ? 284 ARG   A NE  1 
ATOM   1871 C  CZ  . ARG   A 1 284 ? 121.268 91.306  108.156 1.00 87.93  ? 284 ARG   A CZ  1 
ATOM   1872 N  NH1 . ARG   A 1 284 ? 121.555 91.850  106.986 1.00 87.93  ? 284 ARG   A NH1 1 
ATOM   1873 N  NH2 . ARG   A 1 284 ? 120.567 92.005  109.044 1.00 87.93  ? 284 ARG   A NH2 1 
ATOM   1874 N  N   . LEU   A 1 285 ? 121.482 87.250  112.196 1.00 88.87  ? 285 LEU   A N   1 
ATOM   1875 C  CA  . LEU   A 1 285 ? 120.219 87.640  112.809 1.00 88.87  ? 285 LEU   A CA  1 
ATOM   1876 C  C   . LEU   A 1 285 ? 120.393 88.466  114.078 1.00 88.87  ? 285 LEU   A C   1 
ATOM   1877 O  O   . LEU   A 1 285 ? 119.399 89.002  114.582 1.00 88.87  ? 285 LEU   A O   1 
ATOM   1878 C  CB  . LEU   A 1 285 ? 119.378 86.403  113.135 1.00 88.87  ? 285 LEU   A CB  1 
ATOM   1879 C  CG  . LEU   A 1 285 ? 118.868 85.571  111.960 1.00 88.87  ? 285 LEU   A CG  1 
ATOM   1880 C  CD1 . LEU   A 1 285 ? 118.177 84.319  112.472 1.00 88.87  ? 285 LEU   A CD1 1 
ATOM   1881 C  CD2 . LEU   A 1 285 ? 117.926 86.391  111.096 1.00 88.87  ? 285 LEU   A CD2 1 
ATOM   1882 N  N   . GLU   A 1 286 ? 121.614 88.587  114.603 1.00 93.34  ? 286 GLU   A N   1 
ATOM   1883 C  CA  . GLU   A 1 286 ? 121.800 89.249  115.892 1.00 93.34  ? 286 GLU   A CA  1 
ATOM   1884 C  C   . GLU   A 1 286 ? 121.551 90.751  115.793 1.00 93.34  ? 286 GLU   A C   1 
ATOM   1885 O  O   . GLU   A 1 286 ? 120.915 91.340  116.675 1.00 93.34  ? 286 GLU   A O   1 
ATOM   1886 C  CB  . GLU   A 1 286 ? 123.198 88.953  116.442 1.00 93.34  ? 286 GLU   A CB  1 
ATOM   1887 C  CG  . GLU   A 1 286 ? 124.351 89.420  115.571 1.00 93.34  ? 286 GLU   A CG  1 
ATOM   1888 C  CD  . GLU   A 1 286 ? 124.783 88.374  114.557 1.00 93.34  ? 286 GLU   A CD  1 
ATOM   1889 O  OE1 . GLU   A 1 286 ? 124.011 87.424  114.310 1.00 93.34  ? 286 GLU   A OE1 1 
ATOM   1890 O  OE2 . GLU   A 1 286 ? 125.896 88.503  114.011 1.00 93.34  ? 286 GLU   A OE2 1 
ATOM   1891 N  N   . ASP   A 1 287 ? 122.043 91.389  114.735 1.00 90.48  ? 287 ASP   A N   1 
ATOM   1892 C  CA  . ASP   A 1 287 ? 121.801 92.814  114.566 1.00 90.48  ? 287 ASP   A CA  1 
ATOM   1893 C  C   . ASP   A 1 287 ? 120.324 93.049  114.247 1.00 90.48  ? 287 ASP   A C   1 
ATOM   1894 O  O   . ASP   A 1 287 ? 119.686 92.209  113.598 1.00 90.48  ? 287 ASP   A O   1 
ATOM   1895 C  CB  . ASP   A 1 287 ? 122.693 93.394  113.464 1.00 90.48  ? 287 ASP   A CB  1 
ATOM   1896 C  CG  . ASP   A 1 287 ? 122.580 92.634  112.157 1.00 90.48  ? 287 ASP   A CG  1 
ATOM   1897 O  OD1 . ASP   A 1 287 ? 121.929 91.570  112.134 1.00 90.48  ? 287 ASP   A OD1 1 
ATOM   1898 O  OD2 . ASP   A 1 287 ? 123.146 93.102  111.146 1.00 90.48  ? 287 ASP   A OD2 1 
ATOM   1899 N  N   . PRO   A 1 288 ? 119.746 94.171  114.683 1.00 82.40  ? 288 PRO   A N   1 
ATOM   1900 C  CA  . PRO   A 1 288 ? 118.300 94.346  114.538 1.00 82.40  ? 288 PRO   A CA  1 
ATOM   1901 C  C   . PRO   A 1 288 ? 117.864 94.909  113.198 1.00 82.40  ? 288 PRO   A C   1 
ATOM   1902 O  O   . PRO   A 1 288 ? 116.670 95.184  113.035 1.00 82.40  ? 288 PRO   A O   1 
ATOM   1903 C  CB  . PRO   A 1 288 ? 117.976 95.298  115.689 1.00 82.40  ? 288 PRO   A CB  1 
ATOM   1904 C  CG  . PRO   A 1 288 ? 119.177 96.262  115.671 1.00 82.40  ? 288 PRO   A CG  1 
ATOM   1905 C  CD  . PRO   A 1 288 ? 120.353 95.481  114.994 1.00 82.40  ? 288 PRO   A CD  1 
ATOM   1906 N  N   . GLN   A 1 289 ? 118.778 95.094  112.244 1.00 78.60  ? 289 GLN   A N   1 
ATOM   1907 C  CA  . GLN   A 1 289 ? 118.403 95.644  110.946 1.00 78.60  ? 289 GLN   A CA  1 
ATOM   1908 C  C   . GLN   A 1 289 ? 117.367 94.766  110.251 1.00 78.60  ? 289 GLN   A C   1 
ATOM   1909 O  O   . GLN   A 1 289 ? 116.329 95.254  109.785 1.00 78.60  ? 289 GLN   A O   1 
ATOM   1910 C  CB  . GLN   A 1 289 ? 119.648 95.803  110.070 1.00 78.60  ? 289 GLN   A CB  1 
ATOM   1911 C  CG  . GLN   A 1 289 ? 120.496 97.025  110.385 1.00 78.60  ? 289 GLN   A CG  1 
ATOM   1912 C  CD  . GLN   A 1 289 ? 119.663 98.252  110.699 1.00 78.60  ? 289 GLN   A CD  1 
ATOM   1913 O  OE1 . GLN   A 1 289 ? 119.457 98.594  111.863 1.00 78.60  ? 289 GLN   A OE1 1 
ATOM   1914 N  NE2 . GLN   A 1 289 ? 119.184 98.925  109.659 1.00 78.60  ? 289 GLN   A NE2 1 
ATOM   1915 N  N   . VAL   A 1 290 ? 117.639 93.460  110.175 1.00 76.07  ? 290 VAL   A N   1 
ATOM   1916 C  CA  . VAL   A 1 290 ? 116.759 92.555  109.438 1.00 76.07  ? 290 VAL   A CA  1 
ATOM   1917 C  C   . VAL   A 1 290 ? 115.393 92.463  110.111 1.00 76.07  ? 290 VAL   A C   1 
ATOM   1918 O  O   . VAL   A 1 290 ? 114.352 92.509  109.445 1.00 76.07  ? 290 VAL   A O   1 
ATOM   1919 C  CB  . VAL   A 1 290 ? 117.422 91.174  109.265 1.00 76.07  ? 290 VAL   A CB  1 
ATOM   1920 C  CG1 . VAL   A 1 290 ? 117.632 90.473  110.599 1.00 76.07  ? 290 VAL   A CG1 1 
ATOM   1921 C  CG2 . VAL   A 1 290 ? 116.598 90.306  108.328 1.00 76.07  ? 290 VAL   A CG2 1 
ATOM   1922 N  N   . TRP   A 1 291 ? 115.374 92.353  111.442 1.00 71.03  ? 291 TRP   A N   1 
ATOM   1923 C  CA  . TRP   A 1 291 ? 114.102 92.284  112.152 1.00 71.03  ? 291 TRP   A CA  1 
ATOM   1924 C  C   . TRP   A 1 291 ? 113.310 93.573  111.982 1.00 71.03  ? 291 TRP   A C   1 
ATOM   1925 O  O   . TRP   A 1 291 ? 112.092 93.538  111.768 1.00 71.03  ? 291 TRP   A O   1 
ATOM   1926 C  CB  . TRP   A 1 291 ? 114.337 91.985  113.633 1.00 71.03  ? 291 TRP   A CB  1 
ATOM   1927 C  CG  . TRP   A 1 291 ? 114.768 90.574  113.897 1.00 71.03  ? 291 TRP   A CG  1 
ATOM   1928 C  CD1 . TRP   A 1 291 ? 115.965 90.007  113.569 1.00 71.03  ? 291 TRP   A CD1 1 
ATOM   1929 C  CD2 . TRP   A 1 291 ? 113.999 89.545  114.531 1.00 71.03  ? 291 TRP   A CD2 1 
ATOM   1930 N  NE1 . TRP   A 1 291 ? 115.992 88.693  113.966 1.00 71.03  ? 291 TRP   A NE1 1 
ATOM   1931 C  CE2 . TRP   A 1 291 ? 114.796 88.384  114.558 1.00 71.03  ? 291 TRP   A CE2 1 
ATOM   1932 C  CE3 . TRP   A 1 291 ? 112.714 89.494  115.080 1.00 71.03  ? 291 TRP   A CE3 1 
ATOM   1933 C  CZ2 . TRP   A 1 291 ? 114.351 87.187  115.112 1.00 71.03  ? 291 TRP   A CZ2 1 
ATOM   1934 C  CZ3 . TRP   A 1 291 ? 112.275 88.305  115.629 1.00 71.03  ? 291 TRP   A CZ3 1 
ATOM   1935 C  CH2 . TRP   A 1 291 ? 113.091 87.168  115.641 1.00 71.03  ? 291 TRP   A CH2 1 
ATOM   1936 N  N   . ILE   A 1 292 ? 113.987 94.721  112.064 1.00 74.57  ? 292 ILE   A N   1 
ATOM   1937 C  CA  . ILE   A 1 292 ? 113.302 96.002  111.915 1.00 74.57  ? 292 ILE   A CA  1 
ATOM   1938 C  C   . ILE   A 1 292 ? 112.679 96.114  110.530 1.00 74.57  ? 292 ILE   A C   1 
ATOM   1939 O  O   . ILE   A 1 292 ? 111.501 96.462  110.391 1.00 74.57  ? 292 ILE   A O   1 
ATOM   1940 C  CB  . ILE   A 1 292 ? 114.265 97.169  112.200 1.00 74.57  ? 292 ILE   A CB  1 
ATOM   1941 C  CG1 . ILE   A 1 292 ? 114.519 97.299  113.702 1.00 74.57  ? 292 ILE   A CG1 1 
ATOM   1942 C  CG2 . ILE   A 1 292 ? 113.710 98.471  111.645 1.00 74.57  ? 292 ILE   A CG2 1 
ATOM   1943 C  CD1 . ILE   A 1 292 ? 113.285 97.646  114.500 1.00 74.57  ? 292 ILE   A CD1 1 
ATOM   1944 N  N   . ASP   A 1 293 ? 113.450 95.806  109.482 1.00 74.23  ? 293 ASP   A N   1 
ATOM   1945 C  CA  . ASP   A 1 293 ? 112.908 95.973  108.136 1.00 74.23  ? 293 ASP   A CA  1 
ATOM   1946 C  C   . ASP   A 1 293 ? 111.802 94.960  107.854 1.00 74.23  ? 293 ASP   A C   1 
ATOM   1947 O  O   . ASP   A 1 293 ? 110.810 95.290  107.197 1.00 74.23  ? 293 ASP   A O   1 
ATOM   1948 C  CB  . ASP   A 1 293 ? 114.010 95.909  107.071 1.00 74.23  ? 293 ASP   A CB  1 
ATOM   1949 C  CG  . ASP   A 1 293 ? 114.706 94.568  107.001 1.00 74.23  ? 293 ASP   A CG  1 
ATOM   1950 O  OD1 . ASP   A 1 293 ? 115.929 94.537  107.234 1.00 74.23  ? 293 ASP   A OD1 1 
ATOM   1951 O  OD2 . ASP   A 1 293 ? 114.048 93.550  106.706 1.00 74.23  ? 293 ASP   A OD2 1 
ATOM   1952 N  N   . ALA   A 1 294 ? 111.930 93.733  108.368 1.00 72.63  ? 294 ALA   A N   1 
ATOM   1953 C  CA  . ALA   A 1 294 ? 110.885 92.735  108.149 1.00 72.63  ? 294 ALA   A CA  1 
ATOM   1954 C  C   . ALA   A 1 294 ? 109.587 93.125  108.851 1.00 72.63  ? 294 ALA   A C   1 
ATOM   1955 O  O   . ALA   A 1 294 ? 108.502 93.071  108.255 1.00 72.63  ? 294 ALA   A O   1 
ATOM   1956 C  CB  . ALA   A 1 294 ? 111.364 91.363  108.622 1.00 72.63  ? 294 ALA   A CB  1 
ATOM   1957 N  N   . GLY   A 1 295 ? 109.676 93.512  110.126 1.00 67.92  ? 295 GLY   A N   1 
ATOM   1958 C  CA  . GLY   A 1 295 ? 108.483 93.945  110.833 1.00 67.92  ? 295 GLY   A CA  1 
ATOM   1959 C  C   . GLY   A 1 295 ? 107.848 95.166  110.199 1.00 67.92  ? 295 GLY   A C   1 
ATOM   1960 O  O   . GLY   A 1 295 ? 106.623 95.240  110.059 1.00 67.92  ? 295 GLY   A O   1 
ATOM   1961 N  N   . THR   A 1 296 ? 108.670 96.133  109.785 1.00 66.15  ? 296 THR   A N   1 
ATOM   1962 C  CA  . THR   A 1 296 ? 108.125 97.323  109.151 1.00 66.15  ? 296 THR   A CA  1 
ATOM   1963 C  C   . THR   A 1 296 ? 107.508 97.003  107.797 1.00 66.15  ? 296 THR   A C   1 
ATOM   1964 O  O   . THR   A 1 296 ? 106.537 97.646  107.402 1.00 66.15  ? 296 THR   A O   1 
ATOM   1965 C  CB  . THR   A 1 296 ? 109.207 98.388  109.008 1.00 66.15  ? 296 THR   A CB  1 
ATOM   1966 O  OG1 . THR   A 1 296 ? 110.390 97.795  108.466 1.00 66.15  ? 296 THR   A OG1 1 
ATOM   1967 C  CG2 . THR   A 1 296 ? 109.529 98.978  110.365 1.00 66.15  ? 296 THR   A CG2 1 
ATOM   1968 N  N   . GLN   A 1 297 ? 108.041 96.014  107.077 1.00 68.36  ? 297 GLN   A N   1 
ATOM   1969 C  CA  . GLN   A 1 297 ? 107.408 95.598  105.830 1.00 68.36  ? 297 GLN   A CA  1 
ATOM   1970 C  C   . GLN   A 1 297 ? 106.051 94.957  106.086 1.00 68.36  ? 297 GLN   A C   1 
ATOM   1971 O  O   . GLN   A 1 297 ? 105.082 95.216  105.362 1.00 68.36  ? 297 GLN   A O   1 
ATOM   1972 C  CB  . GLN   A 1 297 ? 108.316 94.641  105.064 1.00 68.36  ? 297 GLN   A CB  1 
ATOM   1973 C  CG  . GLN   A 1 297 ? 107.640 94.047  103.853 1.00 68.36  ? 297 GLN   A CG  1 
ATOM   1974 C  CD  . GLN   A 1 297 ? 107.919 94.846  102.605 1.00 68.36  ? 297 GLN   A CD  1 
ATOM   1975 O  OE1 . GLN   A 1 297 ? 109.035 95.318  102.394 1.00 68.36  ? 297 GLN   A OE1 1 
ATOM   1976 N  NE2 . GLN   A 1 297 ? 106.897 95.026  101.777 1.00 68.36  ? 297 GLN   A NE2 1 
ATOM   1977 N  N   . ILE   A 1 298 ? 105.963 94.109  107.114 1.00 67.93  ? 298 ILE   A N   1 
ATOM   1978 C  CA  . ILE   A 1 298 ? 104.660 93.562  107.491 1.00 67.93  ? 298 ILE   A CA  1 
ATOM   1979 C  C   . ILE   A 1 298 ? 103.686 94.686  107.805 1.00 67.93  ? 298 ILE   A C   1 
ATOM   1980 O  O   . ILE   A 1 298 ? 102.524 94.659  107.382 1.00 67.93  ? 298 ILE   A O   1 
ATOM   1981 C  CB  . ILE   A 1 298 ? 104.789 92.590  108.678 1.00 67.93  ? 298 ILE   A CB  1 
ATOM   1982 C  CG1 . ILE   A 1 298 ? 105.712 91.434  108.322 1.00 67.93  ? 298 ILE   A CG1 1 
ATOM   1983 C  CG2 . ILE   A 1 298 ? 103.426 92.051  109.064 1.00 67.93  ? 298 ILE   A CG2 1 
ATOM   1984 C  CD1 . ILE   A 1 298 ? 105.192 90.634  107.167 1.00 67.93  ? 298 ILE   A CD1 1 
ATOM   1985 N  N   . PHE   A 1 299 ? 104.143 95.695  108.544 1.00 64.65  ? 299 PHE   A N   1 
ATOM   1986 C  CA  . PHE   A 1 299 ? 103.258 96.781  108.945 1.00 64.65  ? 299 PHE   A CA  1 
ATOM   1987 C  C   . PHE   A 1 299 ? 103.013 97.784  107.823 1.00 64.65  ? 299 PHE   A C   1 
ATOM   1988 O  O   . PHE   A 1 299 ? 102.104 98.613  107.939 1.00 64.65  ? 299 PHE   A O   1 
ATOM   1989 C  CB  . PHE   A 1 299 ? 103.835 97.478  110.177 1.00 64.65  ? 299 PHE   A CB  1 
ATOM   1990 C  CG  . PHE   A 1 299 ? 103.667 96.691  111.449 1.00 64.65  ? 299 PHE   A CG  1 
ATOM   1991 C  CD1 . PHE   A 1 299 ? 104.039 95.358  111.512 1.00 64.65  ? 299 PHE   A CD1 1 
ATOM   1992 C  CD2 . PHE   A 1 299 ? 103.143 97.280  112.581 1.00 64.65  ? 299 PHE   A CD2 1 
ATOM   1993 C  CE1 . PHE   A 1 299 ? 103.890 94.632  112.670 1.00 64.65  ? 299 PHE   A CE1 1 
ATOM   1994 C  CE2 . PHE   A 1 299 ? 102.993 96.552  113.744 1.00 64.65  ? 299 PHE   A CE2 1 
ATOM   1995 C  CZ  . PHE   A 1 299 ? 103.367 95.230  113.788 1.00 64.65  ? 299 PHE   A CZ  1 
ATOM   1996 N  N   . PHE   A 1 300 ? 103.800 97.723  106.752 1.00 63.61  ? 300 PHE   A N   1 
ATOM   1997 C  CA  . PHE   A 1 300 ? 103.718 98.621  105.610 1.00 63.61  ? 300 PHE   A CA  1 
ATOM   1998 C  C   . PHE   A 1 300 ? 102.785 98.084  104.531 1.00 63.61  ? 300 PHE   A C   1 
ATOM   1999 O  O   . PHE   A 1 300 ? 101.940 98.821  104.015 1.00 63.61  ? 300 PHE   A O   1 
ATOM   2000 C  CB  . PHE   A 1 300 ? 105.127 98.829  105.043 1.00 63.61  ? 300 PHE   A CB  1 
ATOM   2001 C  CG  . PHE   A 1 300 ? 105.299 100.096 104.258 1.00 63.61  ? 300 PHE   A CG  1 
ATOM   2002 C  CD1 . PHE   A 1 300 ? 105.381 101.320 104.900 1.00 63.61  ? 300 PHE   A CD1 1 
ATOM   2003 C  CD2 . PHE   A 1 300 ? 105.410 100.058 102.879 1.00 63.61  ? 300 PHE   A CD2 1 
ATOM   2004 C  CE1 . PHE   A 1 300 ? 105.552 102.483 104.179 1.00 63.61  ? 300 PHE   A CE1 1 
ATOM   2005 C  CE2 . PHE   A 1 300 ? 105.582 101.217 102.153 1.00 63.61  ? 300 PHE   A CE2 1 
ATOM   2006 C  CZ  . PHE   A 1 300 ? 105.653 102.431 102.803 1.00 63.61  ? 300 PHE   A CZ  1 
ATOM   2007 N  N   . SER   A 1 301 ? 102.927 96.801  104.187 1.00 61.94  ? 301 SER   A N   1 
ATOM   2008 C  CA  . SER   A 1 301 ? 102.127 96.228  103.108 1.00 61.94  ? 301 SER   A CA  1 
ATOM   2009 C  C   . SER   A 1 301 ? 100.642 96.236  103.446 1.00 61.94  ? 301 SER   A C   1 
ATOM   2010 O  O   . SER   A 1 301 ? 99.806  96.537  102.588 1.00 61.94  ? 301 SER   A O   1 
ATOM   2011 C  CB  . SER   A 1 301 ? 102.598 94.808  102.799 1.00 61.94  ? 301 SER   A CB  1 
ATOM   2012 O  OG  . SER   A 1 301 ? 103.940 94.801  102.348 1.00 61.94  ? 301 SER   A OG  1 
ATOM   2013 N  N   . TYR   A 1 302 ? 100.292 95.907  104.686 1.00 65.46  ? 302 TYR   A N   1 
ATOM   2014 C  CA  . TYR   A 1 302 ? 98.897  95.880  105.103 1.00 65.46  ? 302 TYR   A CA  1 
ATOM   2015 C  C   . TYR   A 1 302 ? 98.416  97.232  105.610 1.00 65.46  ? 302 TYR   A C   1 
ATOM   2016 O  O   . TYR   A 1 302 ? 97.273  97.332  106.068 1.00 65.46  ? 302 TYR   A O   1 
ATOM   2017 C  CB  . TYR   A 1 302 ? 98.667  94.824  106.193 1.00 65.46  ? 302 TYR   A CB  1 
ATOM   2018 C  CG  . TYR   A 1 302 ? 99.043  93.398  105.843 1.00 65.46  ? 302 TYR   A CG  1 
ATOM   2019 C  CD1 . TYR   A 1 302 ? 99.470  93.051  104.571 1.00 65.46  ? 302 TYR   A CD1 1 
ATOM   2020 C  CD2 . TYR   A 1 302 ? 98.965  92.395  106.798 1.00 65.46  ? 302 TYR   A CD2 1 
ATOM   2021 C  CE1 . TYR   A 1 302 ? 99.812  91.753  104.259 1.00 65.46  ? 302 TYR   A CE1 1 
ATOM   2022 C  CE2 . TYR   A 1 302 ? 99.303  91.095  106.495 1.00 65.46  ? 302 TYR   A CE2 1 
ATOM   2023 C  CZ  . TYR   A 1 302 ? 99.726  90.779  105.225 1.00 65.46  ? 302 TYR   A CZ  1 
ATOM   2024 O  OH  . TYR   A 1 302 ? 100.065 89.484  104.920 1.00 65.46  ? 302 TYR   A OH  1 
ATOM   2025 N  N   . ALA   A 1 303 ? 99.267  98.259  105.561 1.00 61.77  ? 303 ALA   A N   1 
ATOM   2026 C  CA  . ALA   A 1 303 ? 98.894  99.630  105.914 1.00 61.77  ? 303 ALA   A CA  1 
ATOM   2027 C  C   . ALA   A 1 303 ? 98.396  99.739  107.354 1.00 61.77  ? 303 ALA   A C   1 
ATOM   2028 O  O   . ALA   A 1 303 ? 97.393  100.398 107.633 1.00 61.77  ? 303 ALA   A O   1 
ATOM   2029 C  CB  . ALA   A 1 303 ? 97.854  100.188 104.940 1.00 61.77  ? 303 ALA   A CB  1 
ATOM   2030 N  N   . ILE   A 1 304 ? 99.099  99.087  108.282 1.00 60.01  ? 304 ILE   A N   1 
ATOM   2031 C  CA  . ILE   A 1 304 ? 98.788  99.262  109.695 1.00 60.01  ? 304 ILE   A CA  1 
ATOM   2032 C  C   . ILE   A 1 304 ? 99.221  100.659 110.128 1.00 60.01  ? 304 ILE   A C   1 
ATOM   2033 O  O   . ILE   A 1 304 ? 100.208 101.213 109.627 1.00 60.01  ? 304 ILE   A O   1 
ATOM   2034 C  CB  . ILE   A 1 304 ? 99.460  98.180  110.565 1.00 60.01  ? 304 ILE   A CB  1 
ATOM   2035 C  CG1 . ILE   A 1 304 ? 98.952  96.782  110.218 1.00 60.01  ? 304 ILE   A CG1 1 
ATOM   2036 C  CG2 . ILE   A 1 304 ? 99.224  98.426  112.045 1.00 60.01  ? 304 ILE   A CG2 1 
ATOM   2037 C  CD1 . ILE   A 1 304 ? 99.728  96.107  109.139 1.00 60.01  ? 304 ILE   A CD1 1 
ATOM   2038 N  N   . CYS   A 1 305 ? 98.458  101.245 111.051 1.00 62.05  ? 305 CYS   A N   1 
ATOM   2039 C  CA  . CYS   A 1 305 ? 98.751  102.508 111.721 1.00 62.05  ? 305 CYS   A CA  1 
ATOM   2040 C  C   . CYS   A 1 305 ? 98.675  103.711 110.791 1.00 62.05  ? 305 CYS   A C   1 
ATOM   2041 O  O   . CYS   A 1 305 ? 99.218  104.767 111.131 1.00 62.05  ? 305 CYS   A O   1 
ATOM   2042 C  CB  . CYS   A 1 305 ? 100.130 102.503 112.398 1.00 62.05  ? 305 CYS   A CB  1 
ATOM   2043 S  SG  . CYS   A 1 305 ? 100.290 101.335 113.765 1.00 62.05  ? 305 CYS   A SG  1 
ATOM   2044 N  N   . LEU   A 1 306 ? 98.038  103.590 109.629 1.00 62.06  ? 306 LEU   A N   1 
ATOM   2045 C  CA  . LEU   A 1 306 ? 97.882  104.714 108.716 1.00 62.06  ? 306 LEU   A CA  1 
ATOM   2046 C  C   . LEU   A 1 306 ? 96.519  105.383 108.821 1.00 62.06  ? 306 LEU   A C   1 
ATOM   2047 O  O   . LEU   A 1 306 ? 96.271  106.362 108.110 1.00 62.06  ? 306 LEU   A O   1 
ATOM   2048 C  CB  . LEU   A 1 306 ? 98.116  104.261 107.273 1.00 62.06  ? 306 LEU   A CB  1 
ATOM   2049 C  CG  . LEU   A 1 306 ? 99.491  103.673 106.966 1.00 62.06  ? 306 LEU   A CG  1 
ATOM   2050 C  CD1 . LEU   A 1 306 ? 99.633  103.425 105.480 1.00 62.06  ? 306 LEU   A CD1 1 
ATOM   2051 C  CD2 . LEU   A 1 306 ? 100.585 104.593 107.459 1.00 62.06  ? 306 LEU   A CD2 1 
ATOM   2052 N  N   . GLY   A 1 307 ? 95.632  104.884 109.679 1.00 73.42  ? 307 GLY   A N   1 
ATOM   2053 C  CA  . GLY   A 1 307 ? 94.323  105.484 109.827 1.00 73.42  ? 307 GLY   A CA  1 
ATOM   2054 C  C   . GLY   A 1 307 ? 93.406  105.329 108.638 1.00 73.42  ? 307 GLY   A C   1 
ATOM   2055 O  O   . GLY   A 1 307 ? 92.403  106.043 108.553 1.00 73.42  ? 307 GLY   A O   1 
ATOM   2056 N  N   . ALA   A 1 308 ? 93.716  104.420 107.715 1.00 80.29  ? 308 ALA   A N   1 
ATOM   2057 C  CA  . ALA   A 1 308 ? 92.900  104.210 106.526 1.00 80.29  ? 308 ALA   A CA  1 
ATOM   2058 C  C   . ALA   A 1 308 ? 91.900  103.074 106.712 1.00 80.29  ? 308 ALA   A C   1 
ATOM   2059 O  O   . ALA   A 1 308 ? 90.713  103.231 106.407 1.00 80.29  ? 308 ALA   A O   1 
ATOM   2060 C  CB  . ALA   A 1 308 ? 93.797  103.931 105.317 1.00 80.29  ? 308 ALA   A CB  1 
ATOM   2061 N  N   . MET   A 1 309 ? 92.367  101.924 107.205 1.00 84.26  ? 309 MET   A N   1 
ATOM   2062 C  CA  . MET   A 1 309 ? 91.474  100.789 107.414 1.00 84.26  ? 309 MET   A CA  1 
ATOM   2063 C  C   . MET   A 1 309 ? 90.416  101.103 108.462 1.00 84.26  ? 309 MET   A C   1 
ATOM   2064 O  O   . MET   A 1 309 ? 89.265  100.664 108.345 1.00 84.26  ? 309 MET   A O   1 
ATOM   2065 C  CB  . MET   A 1 309 ? 92.279  99.554  107.813 1.00 84.26  ? 309 MET   A CB  1 
ATOM   2066 C  CG  . MET   A 1 309 ? 93.466  99.291  106.912 1.00 84.26  ? 309 MET   A CG  1 
ATOM   2067 S  SD  . MET   A 1 309 ? 92.949  98.622  105.323 1.00 84.26  ? 309 MET   A SD  1 
ATOM   2068 C  CE  . MET   A 1 309 ? 94.397  97.678  104.871 1.00 84.26  ? 309 MET   A CE  1 
ATOM   2069 N  N   . THR   A 1 310 ? 90.787  101.860 109.497 1.00 85.16  ? 310 THR   A N   1 
ATOM   2070 C  CA  . THR   A 1 310 ? 89.817  102.230 110.521 1.00 85.16  ? 310 THR   A CA  1 
ATOM   2071 C  C   . THR   A 1 310 ? 88.675  103.048 109.925 1.00 85.16  ? 310 THR   A C   1 
ATOM   2072 O  O   . THR   A 1 310 ? 87.503  102.788 110.209 1.00 85.16  ? 310 THR   A O   1 
ATOM   2073 C  CB  . THR   A 1 310 ? 90.511  102.977 111.666 1.00 85.16  ? 310 THR   A CB  1 
ATOM   2074 O  OG1 . THR   A 1 310 ? 89.563  103.263 112.703 1.00 85.16  ? 310 THR   A OG1 1 
ATOM   2075 C  CG2 . THR   A 1 310 ? 91.170  104.265 111.189 1.00 85.16  ? 310 THR   A CG2 1 
ATOM   2076 N  N   . SER   A 1 311 ? 88.990  104.009 109.052 1.00 87.02  ? 311 SER   A N   1 
ATOM   2077 C  CA  . SER   A 1 311 ? 87.937  104.793 108.412 1.00 87.02  ? 311 SER   A CA  1 
ATOM   2078 C  C   . SER   A 1 311 ? 87.135  103.948 107.431 1.00 87.02  ? 311 SER   A C   1 
ATOM   2079 O  O   . SER   A 1 311 ? 85.903  104.070 107.355 1.00 87.02  ? 311 SER   A O   1 
ATOM   2080 C  CB  . SER   A 1 311 ? 88.542  106.003 107.703 1.00 87.02  ? 311 SER   A CB  1 
ATOM   2081 O  OG  . SER   A 1 311 ? 89.010  105.651 106.413 1.00 87.02  ? 311 SER   A OG  1 
ATOM   2082 N  N   . LEU   A 1 312 ? 87.817  103.085 106.672 1.00 89.44  ? 312 LEU   A N   1 
ATOM   2083 C  CA  . LEU   A 1 312 ? 87.130  102.258 105.685 1.00 89.44  ? 312 LEU   A CA  1 
ATOM   2084 C  C   . LEU   A 1 312 ? 86.108  101.346 106.350 1.00 89.44  ? 312 LEU   A C   1 
ATOM   2085 O  O   . LEU   A 1 312 ? 84.998  101.165 105.836 1.00 89.44  ? 312 LEU   A O   1 
ATOM   2086 C  CB  . LEU   A 1 312 ? 88.145  101.443 104.884 1.00 89.44  ? 312 LEU   A CB  1 
ATOM   2087 C  CG  . LEU   A 1 312 ? 88.877  102.189 103.765 1.00 89.44  ? 312 LEU   A CG  1 
ATOM   2088 C  CD1 . LEU   A 1 312 ? 89.562  101.211 102.826 1.00 89.44  ? 312 LEU   A CD1 1 
ATOM   2089 C  CD2 . LEU   A 1 312 ? 87.925  103.091 102.997 1.00 89.44  ? 312 LEU   A CD2 1 
ATOM   2090 N  N   . GLY   A 1 313 ? 86.461  100.761 107.493 1.00 89.29  ? 313 GLY   A N   1 
ATOM   2091 C  CA  . GLY   A 1 313 ? 85.484  100.040 108.282 1.00 89.29  ? 313 GLY   A CA  1 
ATOM   2092 C  C   . GLY   A 1 313 ? 84.515  100.914 109.043 1.00 89.29  ? 313 GLY   A C   1 
ATOM   2093 O  O   . GLY   A 1 313 ? 83.433  100.451 109.414 1.00 89.29  ? 313 GLY   A O   1 
ATOM   2094 N  N   . SER   A 1 314 ? 84.878  102.177 109.281 1.00 94.26  ? 314 SER   A N   1 
ATOM   2095 C  CA  . SER   A 1 314 ? 84.018  103.077 110.039 1.00 94.26  ? 314 SER   A CA  1 
ATOM   2096 C  C   . SER   A 1 314 ? 82.889  103.630 109.182 1.00 94.26  ? 314 SER   A C   1 
ATOM   2097 O  O   . SER   A 1 314 ? 81.892  104.134 109.714 1.00 94.26  ? 314 SER   A O   1 
ATOM   2098 C  CB  . SER   A 1 314 ? 84.856  104.213 110.624 1.00 94.26  ? 314 SER   A CB  1 
ATOM   2099 O  OG  . SER   A 1 314 ? 84.054  105.129 111.347 1.00 94.26  ? 314 SER   A OG  1 
ATOM   2100 N  N   . TYR   A 1 315 ? 83.030  103.565 107.857 1.00 95.16  ? 315 TYR   A N   1 
ATOM   2101 C  CA  . TYR   A 1 315 ? 81.935  103.977 106.983 1.00 95.16  ? 315 TYR   A CA  1 
ATOM   2102 C  C   . TYR   A 1 315 ? 80.678  103.158 107.260 1.00 95.16  ? 315 TYR   A C   1 
ATOM   2103 O  O   . TYR   A 1 315 ? 79.568  103.696 107.328 1.00 95.16  ? 315 TYR   A O   1 
ATOM   2104 C  CB  . TYR   A 1 315 ? 82.345  103.852 105.514 1.00 95.16  ? 315 TYR   A CB  1 
ATOM   2105 C  CG  . TYR   A 1 315 ? 83.145  105.024 105.003 1.00 95.16  ? 315 TYR   A CG  1 
ATOM   2106 C  CD1 . TYR   A 1 315 ? 82.811  106.323 105.362 1.00 95.16  ? 315 TYR   A CD1 1 
ATOM   2107 C  CD2 . TYR   A 1 315 ? 84.222  104.836 104.149 1.00 95.16  ? 315 TYR   A CD2 1 
ATOM   2108 C  CE1 . TYR   A 1 315 ? 83.535  107.400 104.897 1.00 95.16  ? 315 TYR   A CE1 1 
ATOM   2109 C  CE2 . TYR   A 1 315 ? 84.952  105.908 103.677 1.00 95.16  ? 315 TYR   A CE2 1 
ATOM   2110 C  CZ  . TYR   A 1 315 ? 84.604  107.188 104.054 1.00 95.16  ? 315 TYR   A CZ  1 
ATOM   2111 O  OH  . TYR   A 1 315 ? 85.328  108.260 103.586 1.00 95.16  ? 315 TYR   A OH  1 
ATOM   2112 N  N   . ASN   A 1 316 ? 80.840  101.847 107.426 1.00 100.31 ? 316 ASN   A N   1 
ATOM   2113 C  CA  . ASN   A 1 316 ? 79.704  100.974 107.689 1.00 100.31 ? 316 ASN   A CA  1 
ATOM   2114 C  C   . ASN   A 1 316 ? 79.149  101.217 109.087 1.00 100.31 ? 316 ASN   A C   1 
ATOM   2115 O  O   . ASN   A 1 316 ? 79.870  101.633 109.997 1.00 100.31 ? 316 ASN   A O   1 
ATOM   2116 C  CB  . ASN   A 1 316 ? 80.122  99.512  107.535 1.00 100.31 ? 316 ASN   A CB  1 
ATOM   2117 C  CG  . ASN   A 1 316 ? 80.476  99.157  106.106 1.00 100.31 ? 316 ASN   A CG  1 
ATOM   2118 O  OD1 . ASN   A 1 316 ? 79.791  99.560  105.167 1.00 100.31 ? 316 ASN   A OD1 1 
ATOM   2119 N  ND2 . ASN   A 1 316 ? 81.553  98.402  105.934 1.00 100.31 ? 316 ASN   A ND2 1 
ATOM   2120 N  N   . LYS   A 1 317 ? 77.853  100.959 109.249 1.00 105.44 ? 317 LYS   A N   1 
ATOM   2121 C  CA  . LYS   A 1 317 ? 77.197  101.096 110.540 1.00 105.44 ? 317 LYS   A CA  1 
ATOM   2122 C  C   . LYS   A 1 317 ? 77.269  99.765  111.294 1.00 105.44 ? 317 LYS   A C   1 
ATOM   2123 O  O   . LYS   A 1 317 ? 77.928  98.813  110.866 1.00 105.44 ? 317 LYS   A O   1 
ATOM   2124 C  CB  . LYS   A 1 317 ? 75.757  101.572 110.348 1.00 105.44 ? 317 LYS   A CB  1 
ATOM   2125 C  CG  . LYS   A 1 317 ? 75.146  102.275 111.556 1.00 105.44 ? 317 LYS   A CG  1 
ATOM   2126 C  CD  . LYS   A 1 317 ? 73.679  102.601 111.333 1.00 105.44 ? 317 LYS   A CD  1 
ATOM   2127 C  CE  . LYS   A 1 317 ? 73.511  103.781 110.390 1.00 105.44 ? 317 LYS   A CE  1 
ATOM   2128 N  NZ  . LYS   A 1 317 ? 72.084  104.190 110.264 1.00 105.44 ? 317 LYS   A NZ  1 
ATOM   2129 N  N   . TYR   A 1 318 ? 76.581  99.695  112.433 1.00 101.78 ? 318 TYR   A N   1 
ATOM   2130 C  CA  . TYR   A 1 318 ? 76.587  98.500  113.263 1.00 101.78 ? 318 TYR   A CA  1 
ATOM   2131 C  C   . TYR   A 1 318 ? 75.994  97.309  112.510 1.00 101.78 ? 318 TYR   A C   1 
ATOM   2132 O  O   . TYR   A 1 318 ? 75.379  97.445  111.449 1.00 101.78 ? 318 TYR   A O   1 
ATOM   2133 C  CB  . TYR   A 1 318 ? 75.796  98.731  114.552 1.00 101.78 ? 318 TYR   A CB  1 
ATOM   2134 C  CG  . TYR   A 1 318 ? 76.430  99.685  115.542 1.00 101.78 ? 318 TYR   A CG  1 
ATOM   2135 C  CD1 . TYR   A 1 318 ? 76.665  101.014 115.212 1.00 101.78 ? 318 TYR   A CD1 1 
ATOM   2136 C  CD2 . TYR   A 1 318 ? 76.781  99.256  116.815 1.00 101.78 ? 318 TYR   A CD2 1 
ATOM   2137 C  CE1 . TYR   A 1 318 ? 77.239  101.886 116.119 1.00 101.78 ? 318 TYR   A CE1 1 
ATOM   2138 C  CE2 . TYR   A 1 318 ? 77.356  100.120 117.729 1.00 101.78 ? 318 TYR   A CE2 1 
ATOM   2139 C  CZ  . TYR   A 1 318 ? 77.583  101.433 117.376 1.00 101.78 ? 318 TYR   A CZ  1 
ATOM   2140 O  OH  . TYR   A 1 318 ? 78.155  102.295 118.282 1.00 101.78 ? 318 TYR   A OH  1 
ATOM   2141 N  N   . LYS   A 1 319 ? 76.188  96.123  113.090 1.00 101.44 ? 319 LYS   A N   1 
ATOM   2142 C  CA  . LYS   A 1 319 ? 75.606  94.880  112.582 1.00 101.44 ? 319 LYS   A CA  1 
ATOM   2143 C  C   . LYS   A 1 319 ? 76.005  94.624  111.130 1.00 101.44 ? 319 LYS   A C   1 
ATOM   2144 O  O   . LYS   A 1 319 ? 75.173  94.312  110.276 1.00 101.44 ? 319 LYS   A O   1 
ATOM   2145 C  CB  . LYS   A 1 319 ? 74.084  94.885  112.740 1.00 101.44 ? 319 LYS   A CB  1 
ATOM   2146 C  CG  . LYS   A 1 319 ? 73.613  95.092  114.170 1.00 101.44 ? 319 LYS   A CG  1 
ATOM   2147 C  CD  . LYS   A 1 319 ? 72.386  95.985  114.226 1.00 101.44 ? 319 LYS   A CD  1 
ATOM   2148 C  CE  . LYS   A 1 319 ? 71.786  96.006  115.621 1.00 101.44 ? 319 LYS   A CE  1 
ATOM   2149 N  NZ  . LYS   A 1 319 ? 72.836  96.098  116.671 1.00 101.44 ? 319 LYS   A NZ  1 
ATOM   2150 N  N   . TYR   A 1 320 ? 77.298  94.762  110.852 1.00 99.69  ? 320 TYR   A N   1 
ATOM   2151 C  CA  . TYR   A 1 320 ? 77.840  94.439  109.544 1.00 99.69  ? 320 TYR   A CA  1 
ATOM   2152 C  C   . TYR   A 1 320 ? 78.049  92.926  109.446 1.00 99.69  ? 320 TYR   A C   1 
ATOM   2153 O  O   . TYR   A 1 320 ? 77.970  92.198  110.439 1.00 99.69  ? 320 TYR   A O   1 
ATOM   2154 C  CB  . TYR   A 1 320 ? 79.130  95.225  109.302 1.00 99.69  ? 320 TYR   A CB  1 
ATOM   2155 C  CG  . TYR   A 1 320 ? 79.723  95.059  107.921 1.00 99.69  ? 320 TYR   A CG  1 
ATOM   2156 C  CD1 . TYR   A 1 320 ? 78.937  95.197  106.786 1.00 99.69  ? 320 TYR   A CD1 1 
ATOM   2157 C  CD2 . TYR   A 1 320 ? 81.071  94.774  107.752 1.00 99.69  ? 320 TYR   A CD2 1 
ATOM   2158 C  CE1 . TYR   A 1 320 ? 79.474  95.046  105.522 1.00 99.69  ? 320 TYR   A CE1 1 
ATOM   2159 C  CE2 . TYR   A 1 320 ? 81.618  94.623  106.494 1.00 99.69  ? 320 TYR   A CE2 1 
ATOM   2160 C  CZ  . TYR   A 1 320 ? 80.814  94.759  105.382 1.00 99.69  ? 320 TYR   A CZ  1 
ATOM   2161 O  OH  . TYR   A 1 320 ? 81.353  94.610  104.125 1.00 99.69  ? 320 TYR   A OH  1 
ATOM   2162 N  N   . ASN   A 1 321 ? 78.310  92.441  108.234 1.00 97.90  ? 321 ASN   A N   1 
ATOM   2163 C  CA  . ASN   A 1 321 ? 78.460  91.010  108.005 1.00 97.90  ? 321 ASN   A CA  1 
ATOM   2164 C  C   . ASN   A 1 321 ? 79.660  90.453  108.768 1.00 97.90  ? 321 ASN   A C   1 
ATOM   2165 O  O   . ASN   A 1 321 ? 80.469  91.189  109.339 1.00 97.90  ? 321 ASN   A O   1 
ATOM   2166 C  CB  . ASN   A 1 321 ? 78.615  90.721  106.512 1.00 97.90  ? 321 ASN   A CB  1 
ATOM   2167 C  CG  . ASN   A 1 321 ? 77.451  91.243  105.693 1.00 97.90  ? 321 ASN   A CG  1 
ATOM   2168 O  OD1 . ASN   A 1 321 ? 77.636  92.012  104.749 1.00 97.90  ? 321 ASN   A OD1 1 
ATOM   2169 N  ND2 . ASN   A 1 321 ? 76.242  90.824  106.048 1.00 97.90  ? 321 ASN   A ND2 1 
ATOM   2170 N  N   . SER   A 1 322 ? 79.761  89.125  108.778 1.00 92.48  ? 322 SER   A N   1 
ATOM   2171 C  CA  . SER   A 1 322 ? 80.867  88.455  109.449 1.00 92.48  ? 322 SER   A CA  1 
ATOM   2172 C  C   . SER   A 1 322 ? 82.192  88.862  108.823 1.00 92.48  ? 322 SER   A C   1 
ATOM   2173 O  O   . SER   A 1 322 ? 82.298  89.013  107.603 1.00 92.48  ? 322 SER   A O   1 
ATOM   2174 C  CB  . SER   A 1 322 ? 80.691  86.938  109.374 1.00 92.48  ? 322 SER   A CB  1 
ATOM   2175 O  OG  . SER   A 1 322 ? 81.288  86.415  108.201 1.00 92.48  ? 322 SER   A OG  1 
ATOM   2176 N  N   . TYR   A 1 323 ? 83.206  89.034  109.665 1.00 90.04  ? 323 TYR   A N   1 
ATOM   2177 C  CA  . TYR   A 1 323 ? 84.496  89.559  109.224 1.00 90.04  ? 323 TYR   A CA  1 
ATOM   2178 C  C   . TYR   A 1 323 ? 85.502  88.472  108.879 1.00 90.04  ? 323 TYR   A C   1 
ATOM   2179 O  O   . TYR   A 1 323 ? 86.708  88.660  109.053 1.00 90.04  ? 323 TYR   A O   1 
ATOM   2180 C  CB  . TYR   A 1 323 ? 85.052  90.499  110.290 1.00 90.04  ? 323 TYR   A CB  1 
ATOM   2181 C  CG  . TYR   A 1 323 ? 84.291  91.798  110.394 1.00 90.04  ? 323 TYR   A CG  1 
ATOM   2182 C  CD1 . TYR   A 1 323 ? 83.235  91.938  111.282 1.00 90.04  ? 323 TYR   A CD1 1 
ATOM   2183 C  CD2 . TYR   A 1 323 ? 84.622  92.882  109.594 1.00 90.04  ? 323 TYR   A CD2 1 
ATOM   2184 C  CE1 . TYR   A 1 323 ? 82.534  93.124  111.377 1.00 90.04  ? 323 TYR   A CE1 1 
ATOM   2185 C  CE2 . TYR   A 1 323 ? 83.927  94.071  109.681 1.00 90.04  ? 323 TYR   A CE2 1 
ATOM   2186 C  CZ  . TYR   A 1 323 ? 82.885  94.187  110.574 1.00 90.04  ? 323 TYR   A CZ  1 
ATOM   2187 O  OH  . TYR   A 1 323 ? 82.190  95.371  110.665 1.00 90.04  ? 323 TYR   A OH  1 
ATOM   2188 N  N   . ARG   A 1 324 ? 85.031  87.322  108.393 1.00 90.20  ? 324 ARG   A N   1 
ATOM   2189 C  CA  . ARG   A 1 324 ? 85.931  86.377  107.745 1.00 90.20  ? 324 ARG   A CA  1 
ATOM   2190 C  C   . ARG   A 1 324 ? 86.598  87.001  106.526 1.00 90.20  ? 324 ARG   A C   1 
ATOM   2191 O  O   . ARG   A 1 324 ? 87.659  86.530  106.095 1.00 90.20  ? 324 ARG   A O   1 
ATOM   2192 C  CB  . ARG   A 1 324 ? 85.164  85.115  107.347 1.00 90.20  ? 324 ARG   A CB  1 
ATOM   2193 C  CG  . ARG   A 1 324 ? 86.040  83.918  107.007 1.00 90.20  ? 324 ARG   A CG  1 
ATOM   2194 C  CD  . ARG   A 1 324 ? 86.492  83.184  108.264 1.00 90.20  ? 324 ARG   A CD  1 
ATOM   2195 N  NE  . ARG   A 1 324 ? 87.285  81.995  107.970 1.00 90.20  ? 324 ARG   A NE  1 
ATOM   2196 C  CZ  . ARG   A 1 324 ? 88.478  81.999  107.390 1.00 90.20  ? 324 ARG   A CZ  1 
ATOM   2197 N  NH1 . ARG   A 1 324 ? 89.079  83.126  107.045 1.00 90.20  ? 324 ARG   A NH1 1 
ATOM   2198 N  NH2 . ARG   A 1 324 ? 89.090  80.841  107.158 1.00 90.20  ? 324 ARG   A NH2 1 
ATOM   2199 N  N   . ASP   A 1 325 ? 85.997  88.056  105.970 1.00 87.26  ? 325 ASP   A N   1 
ATOM   2200 C  CA  . ASP   A 1 325 ? 86.626  88.788  104.879 1.00 87.26  ? 325 ASP   A CA  1 
ATOM   2201 C  C   . ASP   A 1 325 ? 87.957  89.393  105.301 1.00 87.26  ? 325 ASP   A C   1 
ATOM   2202 O  O   . ASP   A 1 325 ? 88.840  89.576  104.462 1.00 87.26  ? 325 ASP   A O   1 
ATOM   2203 C  CB  . ASP   A 1 325 ? 85.690  89.883  104.368 1.00 87.26  ? 325 ASP   A CB  1 
ATOM   2204 C  CG  . ASP   A 1 325 ? 84.283  89.379  104.122 1.00 87.26  ? 325 ASP   A CG  1 
ATOM   2205 O  OD1 . ASP   A 1 325 ? 83.410  89.603  104.987 1.00 87.26  ? 325 ASP   A OD1 1 
ATOM   2206 O  OD2 . ASP   A 1 325 ? 84.048  88.761  103.064 1.00 87.26  ? 325 ASP   A OD2 1 
ATOM   2207 N  N   . CYS   A 1 326 ? 88.124  89.712  106.587 1.00 87.73  ? 326 CYS   A N   1 
ATOM   2208 C  CA  . CYS   A 1 326 ? 89.408  90.233  107.048 1.00 87.73  ? 326 CYS   A CA  1 
ATOM   2209 C  C   . CYS   A 1 326 ? 90.516  89.201  106.878 1.00 87.73  ? 326 CYS   A C   1 
ATOM   2210 O  O   . CYS   A 1 326 ? 91.568  89.496  106.298 1.00 87.73  ? 326 CYS   A O   1 
ATOM   2211 C  CB  . CYS   A 1 326 ? 89.307  90.675  108.507 1.00 87.73  ? 326 CYS   A CB  1 
ATOM   2212 S  SG  . CYS   A 1 326 ? 88.052  91.936  108.817 1.00 87.73  ? 326 CYS   A SG  1 
ATOM   2213 N  N   . MET   A 1 327 ? 90.295  87.982  107.373 1.00 86.82  ? 327 MET   A N   1 
ATOM   2214 C  CA  . MET   A 1 327 ? 91.265  86.912  107.184 1.00 86.82  ? 327 MET   A CA  1 
ATOM   2215 C  C   . MET   A 1 327 ? 91.390  86.491  105.728 1.00 86.82  ? 327 MET   A C   1 
ATOM   2216 O  O   . MET   A 1 327 ? 92.450  85.994  105.335 1.00 86.82  ? 327 MET   A O   1 
ATOM   2217 C  CB  . MET   A 1 327 ? 90.895  85.704  108.047 1.00 86.82  ? 327 MET   A CB  1 
ATOM   2218 C  CG  . MET   A 1 327 ? 90.470  86.059  109.464 1.00 86.82  ? 327 MET   A CG  1 
ATOM   2219 S  SD  . MET   A 1 327 ? 89.583  84.723  110.288 1.00 86.82  ? 327 MET   A SD  1 
ATOM   2220 C  CE  . MET   A 1 327 ? 88.625  85.637  111.494 1.00 86.82  ? 327 MET   A CE  1 
ATOM   2221 N  N   . LEU   A 1 328 ? 90.342  86.670  104.925 1.00 85.62  ? 328 LEU   A N   1 
ATOM   2222 C  CA  . LEU   A 1 328 ? 90.441  86.416  103.493 1.00 85.62  ? 328 LEU   A CA  1 
ATOM   2223 C  C   . LEU   A 1 328 ? 91.353  87.425  102.801 1.00 85.62  ? 328 LEU   A C   1 
ATOM   2224 O  O   . LEU   A 1 328 ? 92.234  87.044  102.025 1.00 85.62  ? 328 LEU   A O   1 
ATOM   2225 C  CB  . LEU   A 1 328 ? 89.046  86.438  102.859 1.00 85.62  ? 328 LEU   A CB  1 
ATOM   2226 C  CG  . LEU   A 1 328 ? 88.230  85.145  102.936 1.00 85.62  ? 328 LEU   A CG  1 
ATOM   2227 C  CD1 . LEU   A 1 328 ? 86.828  85.363  102.388 1.00 85.62  ? 328 LEU   A CD1 1 
ATOM   2228 C  CD2 . LEU   A 1 328 ? 88.928  84.018  102.191 1.00 85.62  ? 328 LEU   A CD2 1 
ATOM   2229 N  N   . LEU   A 1 329 ? 91.157  88.716  103.082 1.00 83.45  ? 329 LEU   A N   1 
ATOM   2230 C  CA  . LEU   A 1 329 ? 91.959  89.758  102.452 1.00 83.45  ? 329 LEU   A CA  1 
ATOM   2231 C  C   . LEU   A 1 329 ? 93.404  89.714  102.928 1.00 83.45  ? 329 LEU   A C   1 
ATOM   2232 O  O   . LEU   A 1 329 ? 94.327  89.980  102.148 1.00 83.45  ? 329 LEU   A O   1 
ATOM   2233 C  CB  . LEU   A 1 329 ? 91.348  91.131  102.731 1.00 83.45  ? 329 LEU   A CB  1 
ATOM   2234 C  CG  . LEU   A 1 329 ? 89.976  91.416  102.121 1.00 83.45  ? 329 LEU   A CG  1 
ATOM   2235 C  CD1 . LEU   A 1 329 ? 89.448  92.758  102.604 1.00 83.45  ? 329 LEU   A CD1 1 
ATOM   2236 C  CD2 . LEU   A 1 329 ? 90.045  91.373  100.604 1.00 83.45  ? 329 LEU   A CD2 1 
ATOM   2237 N  N   . GLY   A 1 330 ? 93.624  89.398  104.206 1.00 80.73  ? 330 GLY   A N   1 
ATOM   2238 C  CA  . GLY   A 1 330 ? 94.988  89.247  104.684 1.00 80.73  ? 330 GLY   A CA  1 
ATOM   2239 C  C   . GLY   A 1 330 ? 95.725  88.144  103.952 1.00 80.73  ? 330 GLY   A C   1 
ATOM   2240 O  O   . GLY   A 1 330 ? 96.873  88.316  103.530 1.00 80.73  ? 330 GLY   A O   1 
ATOM   2241 N  N   . CYS   A 1 331 ? 95.063  86.999  103.774 1.00 81.22  ? 331 CYS   A N   1 
ATOM   2242 C  CA  . CYS   A 1 331 ? 95.662  85.905  103.021 1.00 81.22  ? 331 CYS   A CA  1 
ATOM   2243 C  C   . CYS   A 1 331 ? 95.880  86.292  101.564 1.00 81.22  ? 331 CYS   A C   1 
ATOM   2244 O  O   . CYS   A 1 331 ? 96.898  85.930  100.967 1.00 81.22  ? 331 CYS   A O   1 
ATOM   2245 C  CB  . CYS   A 1 331 ? 94.787  84.656  103.125 1.00 81.22  ? 331 CYS   A CB  1 
ATOM   2246 S  SG  . CYS   A 1 331 ? 94.763  83.905  104.770 1.00 81.22  ? 331 CYS   A SG  1 
ATOM   2247 N  N   . LEU   A 1 332 ? 94.934  87.030  100.976 1.00 81.65  ? 332 LEU   A N   1 
ATOM   2248 C  CA  . LEU   A 1 332 ? 95.090  87.474  99.594  1.00 81.65  ? 332 LEU   A CA  1 
ATOM   2249 C  C   . LEU   A 1 332 ? 96.323  88.355  99.431  1.00 81.65  ? 332 LEU   A C   1 
ATOM   2250 O  O   . LEU   A 1 332 ? 97.123  88.162  98.507  1.00 81.65  ? 332 LEU   A O   1 
ATOM   2251 C  CB  . LEU   A 1 332 ? 93.838  88.222  99.138  1.00 81.65  ? 332 LEU   A CB  1 
ATOM   2252 C  CG  . LEU   A 1 332 ? 93.879  88.786  97.714  1.00 81.65  ? 332 LEU   A CG  1 
ATOM   2253 C  CD1 . LEU   A 1 332 ? 94.004  87.672  96.687  1.00 81.65  ? 332 LEU   A CD1 1 
ATOM   2254 C  CD2 . LEU   A 1 332 ? 92.656  89.647  97.433  1.00 81.65  ? 332 LEU   A CD2 1 
ATOM   2255 N  N   . ASN   A 1 333 ? 96.493  89.332  100.324 1.00 75.53  ? 333 ASN   A N   1 
ATOM   2256 C  CA  . ASN   A 1 333 ? 97.638  90.230  100.215 1.00 75.53  ? 333 ASN   A CA  1 
ATOM   2257 C  C   . ASN   A 1 333 ? 98.944  89.499  100.498 1.00 75.53  ? 333 ASN   A C   1 
ATOM   2258 O  O   . ASN   A 1 333 ? 99.955  89.743  99.826  1.00 75.53  ? 333 ASN   A O   1 
ATOM   2259 C  CB  . ASN   A 1 333 ? 97.476  91.420  101.156 1.00 75.53  ? 333 ASN   A CB  1 
ATOM   2260 C  CG  . ASN   A 1 333 ? 98.454  92.535  100.850 1.00 75.53  ? 333 ASN   A CG  1 
ATOM   2261 O  OD1 . ASN   A 1 333 ? 99.145  92.507  99.833  1.00 75.53  ? 333 ASN   A OD1 1 
ATOM   2262 N  ND2 . ASN   A 1 333 ? 98.504  93.533  101.720 1.00 75.53  ? 333 ASN   A ND2 1 
ATOM   2263 N  N   . SER   A 1 334 ? 98.946  88.601  101.487 1.00 74.88  ? 334 SER   A N   1 
ATOM   2264 C  CA  . SER   A 1 334 ? 100.146 87.820  101.759 1.00 74.88  ? 334 SER   A CA  1 
ATOM   2265 C  C   . SER   A 1 334 ? 100.528 86.977  100.552 1.00 74.88  ? 334 SER   A C   1 
ATOM   2266 O  O   . SER   A 1 334 ? 101.706 86.901  100.188 1.00 74.88  ? 334 SER   A O   1 
ATOM   2267 C  CB  . SER   A 1 334 ? 99.934  86.936  102.986 1.00 74.88  ? 334 SER   A CB  1 
ATOM   2268 O  OG  . SER   A 1 334 ? 98.948  85.949  102.741 1.00 74.88  ? 334 SER   A OG  1 
ATOM   2269 N  N   . GLY   A 1 335 ? 99.543  86.350  99.907  1.00 77.56  ? 335 GLY   A N   1 
ATOM   2270 C  CA  . GLY   A 1 335 ? 99.830  85.565  98.720  1.00 77.56  ? 335 GLY   A CA  1 
ATOM   2271 C  C   . GLY   A 1 335 ? 100.337 86.407  97.567  1.00 77.56  ? 335 GLY   A C   1 
ATOM   2272 O  O   . GLY   A 1 335 ? 101.264 86.007  96.860  1.00 77.56  ? 335 GLY   A O   1 
ATOM   2273 N  N   . THR   A 1 336 ? 99.737  87.582  97.357  1.00 77.60  ? 336 THR   A N   1 
ATOM   2274 C  CA  . THR   A 1 336 ? 100.195 88.466  96.288  1.00 77.60  ? 336 THR   A CA  1 
ATOM   2275 C  C   . THR   A 1 336 ? 101.641 88.891  96.515  1.00 77.60  ? 336 THR   A C   1 
ATOM   2276 O  O   . THR   A 1 336 ? 102.465 88.861  95.591  1.00 77.60  ? 336 THR   A O   1 
ATOM   2277 C  CB  . THR   A 1 336 ? 99.286  89.692  96.192  1.00 77.60  ? 336 THR   A CB  1 
ATOM   2278 O  OG1 . THR   A 1 336 ? 97.934  89.273  95.968  1.00 77.60  ? 336 THR   A OG1 1 
ATOM   2279 C  CG2 . THR   A 1 336 ? 99.728  90.595  95.052  1.00 77.60  ? 336 THR   A CG2 1 
ATOM   2280 N  N   . SER   A 1 337 ? 101.968 89.282  97.750  1.00 77.51  ? 337 SER   A N   1 
ATOM   2281 C  CA  . SER   A 1 337 ? 103.336 89.674  98.070  1.00 77.51  ? 337 SER   A CA  1 
ATOM   2282 C  C   . SER   A 1 337 ? 104.293 88.496  97.939  1.00 77.51  ? 337 SER   A C   1 
ATOM   2283 O  O   . SER   A 1 337 ? 105.441 88.666  97.512  1.00 77.51  ? 337 SER   A O   1 
ATOM   2284 C  CB  . SER   A 1 337 ? 103.393 90.260  99.479  1.00 77.51  ? 337 SER   A CB  1 
ATOM   2285 O  OG  . SER   A 1 337 ? 104.644 90.875  99.726  1.00 77.51  ? 337 SER   A OG  1 
ATOM   2286 N  N   . PHE   A 1 338 ? 103.839 87.295  98.302  1.00 82.29  ? 338 PHE   A N   1 
ATOM   2287 C  CA  . PHE   A 1 338 ? 104.701 86.121  98.247  1.00 82.29  ? 338 PHE   A CA  1 
ATOM   2288 C  C   . PHE   A 1 338 ? 104.966 85.691  96.809  1.00 82.29  ? 338 PHE   A C   1 
ATOM   2289 O  O   . PHE   A 1 338 ? 106.049 85.182  96.500  1.00 82.29  ? 338 PHE   A O   1 
ATOM   2290 C  CB  . PHE   A 1 338 ? 104.066 84.986  99.052  1.00 82.29  ? 338 PHE   A CB  1 
ATOM   2291 C  CG  . PHE   A 1 338 ? 104.951 83.786  99.223  1.00 82.29  ? 338 PHE   A CG  1 
ATOM   2292 C  CD1 . PHE   A 1 338 ? 106.019 83.818  100.103 1.00 82.29  ? 338 PHE   A CD1 1 
ATOM   2293 C  CD2 . PHE   A 1 338 ? 104.705 82.620  98.518  1.00 82.29  ? 338 PHE   A CD2 1 
ATOM   2294 C  CE1 . PHE   A 1 338 ? 106.833 82.714  100.267 1.00 82.29  ? 338 PHE   A CE1 1 
ATOM   2295 C  CE2 . PHE   A 1 338 ? 105.515 81.512  98.680  1.00 82.29  ? 338 PHE   A CE2 1 
ATOM   2296 C  CZ  . PHE   A 1 338 ? 106.581 81.560  99.555  1.00 82.29  ? 338 PHE   A CZ  1 
ATOM   2297 N  N   . VAL   A 1 339 ? 103.996 85.884  95.916  1.00 81.88  ? 339 VAL   A N   1 
ATOM   2298 C  CA  . VAL   A 1 339 ? 104.163 85.450  94.530  1.00 81.88  ? 339 VAL   A CA  1 
ATOM   2299 C  C   . VAL   A 1 339 ? 104.871 86.506  93.687  1.00 81.88  ? 339 VAL   A C   1 
ATOM   2300 O  O   . VAL   A 1 339 ? 105.595 86.166  92.748  1.00 81.88  ? 339 VAL   A O   1 
ATOM   2301 C  CB  . VAL   A 1 339 ? 102.805 85.053  93.911  1.00 81.88  ? 339 VAL   A CB  1 
ATOM   2302 C  CG1 . VAL   A 1 339 ? 102.169 83.915  94.699  1.00 81.88  ? 339 VAL   A CG1 1 
ATOM   2303 C  CG2 . VAL   A 1 339 ? 101.871 86.250  93.815  1.00 81.88  ? 339 VAL   A CG2 1 
ATOM   2304 N  N   . SER   A 1 340 ? 104.682 87.796  93.984  1.00 78.48  ? 340 SER   A N   1 
ATOM   2305 C  CA  . SER   A 1 340 ? 105.394 88.826  93.231  1.00 78.48  ? 340 SER   A CA  1 
ATOM   2306 C  C   . SER   A 1 340 ? 106.899 88.703  93.427  1.00 78.48  ? 340 SER   A C   1 
ATOM   2307 O  O   . SER   A 1 340 ? 107.681 88.892  92.481  1.00 78.48  ? 340 SER   A O   1 
ATOM   2308 C  CB  . SER   A 1 340 ? 104.907 90.213  93.651  1.00 78.48  ? 340 SER   A CB  1 
ATOM   2309 O  OG  . SER   A 1 340 ? 105.752 91.226  93.137  1.00 78.48  ? 340 SER   A OG  1 
ATOM   2310 N  N   . GLY   A 1 341 ? 107.320 88.382  94.652  1.00 77.82  ? 341 GLY   A N   1 
ATOM   2311 C  CA  . GLY   A 1 341 ? 108.730 88.185  94.920  1.00 77.82  ? 341 GLY   A CA  1 
ATOM   2312 C  C   . GLY   A 1 341 ? 109.342 87.081  94.085  1.00 77.82  ? 341 GLY   A C   1 
ATOM   2313 O  O   . GLY   A 1 341 ? 110.527 87.138  93.759  1.00 77.82  ? 341 GLY   A O   1 
ATOM   2314 N  N   . PHE   A 1 342 ? 108.547 86.073  93.714  1.00 84.70  ? 342 PHE   A N   1 
ATOM   2315 C  CA  . PHE   A 1 342 ? 109.057 85.013  92.849  1.00 84.70  ? 342 PHE   A CA  1 
ATOM   2316 C  C   . PHE   A 1 342 ? 109.542 85.581  91.522  1.00 84.70  ? 342 PHE   A C   1 
ATOM   2317 O  O   . PHE   A 1 342 ? 110.693 85.364  91.120  1.00 84.70  ? 342 PHE   A O   1 
ATOM   2318 C  CB  . PHE   A 1 342 ? 107.971 83.963  92.609  1.00 84.70  ? 342 PHE   A CB  1 
ATOM   2319 C  CG  . PHE   A 1 342 ? 107.828 82.968  93.720  1.00 84.70  ? 342 PHE   A CG  1 
ATOM   2320 C  CD1 . PHE   A 1 342 ? 108.867 82.113  94.041  1.00 84.70  ? 342 PHE   A CD1 1 
ATOM   2321 C  CD2 . PHE   A 1 342 ? 106.648 82.879  94.435  1.00 84.70  ? 342 PHE   A CD2 1 
ATOM   2322 C  CE1 . PHE   A 1 342 ? 108.733 81.194  95.062  1.00 84.70  ? 342 PHE   A CE1 1 
ATOM   2323 C  CE2 . PHE   A 1 342 ? 106.508 81.963  95.455  1.00 84.70  ? 342 PHE   A CE2 1 
ATOM   2324 C  CZ  . PHE   A 1 342 ? 107.552 81.119  95.769  1.00 84.70  ? 342 PHE   A CZ  1 
ATOM   2325 N  N   . ALA   A 1 343 ? 108.679 86.337  90.839  1.00 78.41  ? 343 ALA   A N   1 
ATOM   2326 C  CA  . ALA   A 1 343 ? 109.058 86.927  89.561  1.00 78.41  ? 343 ALA   A CA  1 
ATOM   2327 C  C   . ALA   A 1 343 ? 110.204 87.912  89.730  1.00 78.41  ? 343 ALA   A C   1 
ATOM   2328 O  O   . ALA   A 1 343 ? 111.150 87.924  88.928  1.00 78.41  ? 343 ALA   A O   1 
ATOM   2329 C  CB  . ALA   A 1 343 ? 107.851 87.611  88.921  1.00 78.41  ? 343 ALA   A CB  1 
ATOM   2330 N  N   . ILE   A 1 344 ? 110.144 88.741  90.777  1.00 78.59  ? 344 ILE   A N   1 
ATOM   2331 C  CA  . ILE   A 1 344 ? 111.174 89.759  90.957  1.00 78.59  ? 344 ILE   A CA  1 
ATOM   2332 C  C   . ILE   A 1 344 ? 112.534 89.109  91.178  1.00 78.59  ? 344 ILE   A C   1 
ATOM   2333 O  O   . ILE   A 1 344 ? 113.528 89.474  90.543  1.00 78.59  ? 344 ILE   A O   1 
ATOM   2334 C  CB  . ILE   A 1 344 ? 110.810 90.707  92.111  1.00 78.59  ? 344 ILE   A CB  1 
ATOM   2335 C  CG1 . ILE   A 1 344 ? 109.474 91.386  91.832  1.00 78.59  ? 344 ILE   A CG1 1 
ATOM   2336 C  CG2 . ILE   A 1 344 ? 111.883 91.759  92.261  1.00 78.59  ? 344 ILE   A CG2 1 
ATOM   2337 C  CD1 . ILE   A 1 344 ? 109.485 92.221  90.586  1.00 78.59  ? 344 ILE   A CD1 1 
ATOM   2338 N  N   . PHE   A 1 345 ? 112.601 88.124  92.067  1.00 77.50  ? 345 PHE   A N   1 
ATOM   2339 C  CA  . PHE   A 1 345 ? 113.886 87.511  92.346  1.00 77.50  ? 345 PHE   A CA  1 
ATOM   2340 C  C   . PHE   A 1 345 ? 114.362 86.621  91.210  1.00 77.50  ? 345 PHE   A C   1 
ATOM   2341 O  O   . PHE   A 1 345 ? 115.573 86.482  91.029  1.00 77.50  ? 345 PHE   A O   1 
ATOM   2342 C  CB  . PHE   A 1 345 ? 113.824 86.739  93.662  1.00 77.50  ? 345 PHE   A CB  1 
ATOM   2343 C  CG  . PHE   A 1 345 ? 114.139 87.589  94.858  1.00 77.50  ? 345 PHE   A CG  1 
ATOM   2344 C  CD1 . PHE   A 1 345 ? 115.451 87.864  95.201  1.00 77.50  ? 345 PHE   A CD1 1 
ATOM   2345 C  CD2 . PHE   A 1 345 ? 113.123 88.141  95.619  1.00 77.50  ? 345 PHE   A CD2 1 
ATOM   2346 C  CE1 . PHE   A 1 345 ? 115.744 88.656  96.292  1.00 77.50  ? 345 PHE   A CE1 1 
ATOM   2347 C  CE2 . PHE   A 1 345 ? 113.410 88.934  96.713  1.00 77.50  ? 345 PHE   A CE2 1 
ATOM   2348 C  CZ  . PHE   A 1 345 ? 114.722 89.191  97.049  1.00 77.50  ? 345 PHE   A CZ  1 
ATOM   2349 N  N   . SER   A 1 346 ? 113.455 86.063  90.404  1.00 79.75  ? 346 SER   A N   1 
ATOM   2350 C  CA  . SER   A 1 346 ? 113.897 85.354  89.208  1.00 79.75  ? 346 SER   A CA  1 
ATOM   2351 C  C   . SER   A 1 346 ? 114.546 86.309  88.209  1.00 79.75  ? 346 SER   A C   1 
ATOM   2352 O  O   . SER   A 1 346 ? 115.588 85.992  87.619  1.00 79.75  ? 346 SER   A O   1 
ATOM   2353 C  CB  . SER   A 1 346 ? 112.725 84.611  88.569  1.00 79.75  ? 346 SER   A CB  1 
ATOM   2354 O  OG  . SER   A 1 346 ? 111.568 85.420  88.540  1.00 79.75  ? 346 SER   A OG  1 
ATOM   2355 N  N   . ILE   A 1 347 ? 113.952 87.490  88.003  1.00 81.32  ? 347 ILE   A N   1 
ATOM   2356 C  CA  . ILE   A 1 347 ? 114.562 88.408  87.041  1.00 81.32  ? 347 ILE   A CA  1 
ATOM   2357 C  C   . ILE   A 1 347 ? 115.864 88.992  87.592  1.00 81.32  ? 347 ILE   A C   1 
ATOM   2358 O  O   . ILE   A 1 347 ? 116.813 89.222  86.831  1.00 81.32  ? 347 ILE   A O   1 
ATOM   2359 C  CB  . ILE   A 1 347 ? 113.576 89.507  86.590  1.00 81.32  ? 347 ILE   A CB  1 
ATOM   2360 C  CG1 . ILE   A 1 347 ? 113.100 90.367  87.756  1.00 81.32  ? 347 ILE   A CG1 1 
ATOM   2361 C  CG2 . ILE   A 1 347 ? 112.386 88.890  85.871  1.00 81.32  ? 347 ILE   A CG2 1 
ATOM   2362 C  CD1 . ILE   A 1 347 ? 112.011 91.350  87.381  1.00 81.32  ? 347 ILE   A CD1 1 
ATOM   2363 N  N   . LEU   A 1 348 ? 115.951 89.230  88.907  1.00 79.23  ? 348 LEU   A N   1 
ATOM   2364 C  CA  . LEU   A 1 348 ? 117.240 89.612  89.486  1.00 79.23  ? 348 LEU   A CA  1 
ATOM   2365 C  C   . LEU   A 1 348 ? 118.273 88.496  89.365  1.00 79.23  ? 348 LEU   A C   1 
ATOM   2366 O  O   . LEU   A 1 348 ? 119.463 88.768  89.176  1.00 79.23  ? 348 LEU   A O   1 
ATOM   2367 C  CB  . LEU   A 1 348 ? 117.092 90.048  90.945  1.00 79.23  ? 348 LEU   A CB  1 
ATOM   2368 C  CG  . LEU   A 1 348 ? 116.673 91.488  91.267  1.00 79.23  ? 348 LEU   A CG  1 
ATOM   2369 C  CD1 . LEU   A 1 348 ? 115.243 91.826  90.934  1.00 79.23  ? 348 LEU   A CD1 1 
ATOM   2370 C  CD2 . LEU   A 1 348 ? 116.949 91.760  92.737  1.00 79.23  ? 348 LEU   A CD2 1 
ATOM   2371 N  N   . GLY   A 1 349 ? 117.849 87.237  89.477  1.00 85.44  ? 349 GLY   A N   1 
ATOM   2372 C  CA  . GLY   A 1 349 ? 118.774 86.141  89.241  1.00 85.44  ? 349 GLY   A CA  1 
ATOM   2373 C  C   . GLY   A 1 349 ? 119.281 86.118  87.812  1.00 85.44  ? 349 GLY   A C   1 
ATOM   2374 O  O   . GLY   A 1 349 ? 120.463 85.860  87.564  1.00 85.44  ? 349 GLY   A O   1 
ATOM   2375 N  N   . PHE   A 1 350 ? 118.391 86.382  86.853  1.00 89.81  ? 350 PHE   A N   1 
ATOM   2376 C  CA  . PHE   A 1 350 ? 118.819 86.480  85.460  1.00 89.81  ? 350 PHE   A CA  1 
ATOM   2377 C  C   . PHE   A 1 350 ? 119.800 87.630  85.266  1.00 89.81  ? 350 PHE   A C   1 
ATOM   2378 O  O   . PHE   A 1 350 ? 120.799 87.491  84.551  1.00 89.81  ? 350 PHE   A O   1 
ATOM   2379 C  CB  . PHE   A 1 350 ? 117.612 86.656  84.542  1.00 89.81  ? 350 PHE   A CB  1 
ATOM   2380 C  CG  . PHE   A 1 350 ? 117.974 87.088  83.148  1.00 89.81  ? 350 PHE   A CG  1 
ATOM   2381 C  CD1 . PHE   A 1 350 ? 118.737 86.270  82.331  1.00 89.81  ? 350 PHE   A CD1 1 
ATOM   2382 C  CD2 . PHE   A 1 350 ? 117.563 88.317  82.659  1.00 89.81  ? 350 PHE   A CD2 1 
ATOM   2383 C  CE1 . PHE   A 1 350 ? 119.076 86.666  81.052  1.00 89.81  ? 350 PHE   A CE1 1 
ATOM   2384 C  CE2 . PHE   A 1 350 ? 117.898 88.718  81.380  1.00 89.81  ? 350 PHE   A CE2 1 
ATOM   2385 C  CZ  . PHE   A 1 350 ? 118.656 87.891  80.576  1.00 89.81  ? 350 PHE   A CZ  1 
ATOM   2386 N  N   . MET   A 1 351 ? 119.529 88.776  85.893  1.00 87.05  ? 351 MET   A N   1 
ATOM   2387 C  CA  . MET   A 1 351 ? 120.456 89.900  85.804  1.00 87.05  ? 351 MET   A CA  1 
ATOM   2388 C  C   . MET   A 1 351 ? 121.814 89.539  86.394  1.00 87.05  ? 351 MET   A C   1 
ATOM   2389 O  O   . MET   A 1 351 ? 122.858 89.906  85.842  1.00 87.05  ? 351 MET   A O   1 
ATOM   2390 C  CB  . MET   A 1 351 ? 119.873 91.119  86.516  1.00 87.05  ? 351 MET   A CB  1 
ATOM   2391 C  CG  . MET   A 1 351 ? 118.786 91.832  85.741  1.00 87.05  ? 351 MET   A CG  1 
ATOM   2392 S  SD  . MET   A 1 351 ? 118.092 93.202  86.678  1.00 87.05  ? 351 MET   A SD  1 
ATOM   2393 C  CE  . MET   A 1 351 ? 119.471 94.342  86.676  1.00 87.05  ? 351 MET   A CE  1 
ATOM   2394 N  N   . ALA   A 1 352 ? 121.816 88.827  87.524  1.00 94.98  ? 352 ALA   A N   1 
ATOM   2395 C  CA  . ALA   A 1 352 ? 123.070 88.422  88.150  1.00 94.98  ? 352 ALA   A CA  1 
ATOM   2396 C  C   . ALA   A 1 352 ? 123.849 87.460  87.264  1.00 94.98  ? 352 ALA   A C   1 
ATOM   2397 O  O   . ALA   A 1 352 ? 125.072 87.582  87.129  1.00 94.98  ? 352 ALA   A O   1 
ATOM   2398 C  CB  . ALA   A 1 352 ? 122.793 87.791  89.514  1.00 94.98  ? 352 ALA   A CB  1 
ATOM   2399 N  N   . GLN   A 1 353 ? 123.160 86.494  86.653  1.00 101.34 ? 353 GLN   A N   1 
ATOM   2400 C  CA  . GLN   A 1 353 ? 123.844 85.560  85.766  1.00 101.34 ? 353 GLN   A CA  1 
ATOM   2401 C  C   . GLN   A 1 353 ? 124.291 86.224  84.471  1.00 101.34 ? 353 GLN   A C   1 
ATOM   2402 O  O   . GLN   A 1 353 ? 125.219 85.728  83.824  1.00 101.34 ? 353 GLN   A O   1 
ATOM   2403 C  CB  . GLN   A 1 353 ? 122.946 84.356  85.465  1.00 101.34 ? 353 GLN   A CB  1 
ATOM   2404 C  CG  . GLN   A 1 353 ? 121.883 84.595  84.404  1.00 101.34 ? 353 GLN   A CG  1 
ATOM   2405 C  CD  . GLN   A 1 353 ? 122.328 84.171  83.017  1.00 101.34 ? 353 GLN   A CD  1 
ATOM   2406 O  OE1 . GLN   A 1 353 ? 123.123 83.245  82.864  1.00 101.34 ? 353 GLN   A OE1 1 
ATOM   2407 N  NE2 . GLN   A 1 353 ? 121.816 84.852  81.998  1.00 101.34 ? 353 GLN   A NE2 1 
ATOM   2408 N  N   . GLU   A 1 354 ? 123.657 87.331  84.080  1.00 103.55 ? 354 GLU   A N   1 
ATOM   2409 C  CA  . GLU   A 1 354 ? 124.061 88.028  82.864  1.00 103.55 ? 354 GLU   A CA  1 
ATOM   2410 C  C   . GLU   A 1 354 ? 125.270 88.922  83.109  1.00 103.55 ? 354 GLU   A C   1 
ATOM   2411 O  O   . GLU   A 1 354 ? 126.271 88.835  82.389  1.00 103.55 ? 354 GLU   A O   1 
ATOM   2412 C  CB  . GLU   A 1 354 ? 122.892 88.849  82.317  1.00 103.55 ? 354 GLU   A CB  1 
ATOM   2413 C  CG  . GLU   A 1 354 ? 123.149 89.452  80.948  1.00 103.55 ? 354 GLU   A CG  1 
ATOM   2414 C  CD  . GLU   A 1 354 ? 123.747 88.454  79.978  1.00 103.55 ? 354 GLU   A CD  1 
ATOM   2415 O  OE1 . GLU   A 1 354 ? 123.000 87.584  79.483  1.00 103.55 ? 354 GLU   A OE1 1 
ATOM   2416 O  OE2 . GLU   A 1 354 ? 124.964 88.538  79.712  1.00 103.55 ? 354 GLU   A OE2 1 
ATOM   2417 N  N   . GLN   A 1 355 ? 125.194 89.791  84.120  1.00 103.60 ? 355 GLN   A N   1 
ATOM   2418 C  CA  . GLN   A 1 355 ? 126.288 90.722  84.377  1.00 103.60 ? 355 GLN   A CA  1 
ATOM   2419 C  C   . GLN   A 1 355 ? 127.543 90.006  84.860  1.00 103.60 ? 355 GLN   A C   1 
ATOM   2420 O  O   . GLN   A 1 355 ? 128.659 90.454  84.570  1.00 103.60 ? 355 GLN   A O   1 
ATOM   2421 C  CB  . GLN   A 1 355 ? 125.852 91.779  85.392  1.00 103.60 ? 355 GLN   A CB  1 
ATOM   2422 C  CG  . GLN   A 1 355 ? 124.579 92.516  85.009  1.00 103.60 ? 355 GLN   A CG  1 
ATOM   2423 C  CD  . GLN   A 1 355 ? 124.619 93.985  85.381  1.00 103.60 ? 355 GLN   A CD  1 
ATOM   2424 O  OE1 . GLN   A 1 355 ? 125.691 94.584  85.473  1.00 103.60 ? 355 GLN   A OE1 1 
ATOM   2425 N  NE2 . GLN   A 1 355 ? 123.449 94.573  85.597  1.00 103.60 ? 355 GLN   A NE2 1 
ATOM   2426 N  N   . GLY   A 1 356 ? 127.389 88.904  85.587  1.00 107.25 ? 356 GLY   A N   1 
ATOM   2427 C  CA  . GLY   A 1 356 ? 128.524 88.149  86.073  1.00 107.25 ? 356 GLY   A CA  1 
ATOM   2428 C  C   . GLY   A 1 356 ? 129.040 88.549  87.436  1.00 107.25 ? 356 GLY   A C   1 
ATOM   2429 O  O   . GLY   A 1 356 ? 130.091 88.047  87.852  1.00 107.25 ? 356 GLY   A O   1 
ATOM   2430 N  N   . VAL   A 1 357 ? 128.342 89.431  88.144  1.00 102.48 ? 357 VAL   A N   1 
ATOM   2431 C  CA  . VAL   A 1 357 ? 128.751 89.866  89.470  1.00 102.48 ? 357 VAL   A CA  1 
ATOM   2432 C  C   . VAL   A 1 357 ? 127.838 89.215  90.505  1.00 102.48 ? 357 VAL   A C   1 
ATOM   2433 O  O   . VAL   A 1 357 ? 126.851 88.558  90.175  1.00 102.48 ? 357 VAL   A O   1 
ATOM   2434 C  CB  . VAL   A 1 357 ? 128.746 91.401  89.605  1.00 102.48 ? 357 VAL   A CB  1 
ATOM   2435 C  CG1 . VAL   A 1 357 ? 129.844 92.010  88.748  1.00 102.48 ? 357 VAL   A CG1 1 
ATOM   2436 C  CG2 . VAL   A 1 357 ? 127.391 91.963  89.217  1.00 102.48 ? 357 VAL   A CG2 1 
ATOM   2437 N  N   . ASP   A 1 358 ? 128.186 89.402  91.777  1.00 96.28  ? 358 ASP   A N   1 
ATOM   2438 C  CA  . ASP   A 1 358 ? 127.435 88.786  92.861  1.00 96.28  ? 358 ASP   A CA  1 
ATOM   2439 C  C   . ASP   A 1 358 ? 126.003 89.309  92.891  1.00 96.28  ? 358 ASP   A C   1 
ATOM   2440 O  O   . ASP   A 1 358 ? 125.721 90.440  92.487  1.00 96.28  ? 358 ASP   A O   1 
ATOM   2441 C  CB  . ASP   A 1 358 ? 128.118 89.054  94.202  1.00 96.28  ? 358 ASP   A CB  1 
ATOM   2442 C  CG  . ASP   A 1 358 ? 129.529 88.505  94.257  1.00 96.28  ? 358 ASP   A CG  1 
ATOM   2443 O  OD1 . ASP   A 1 358 ? 129.828 87.557  93.501  1.00 96.28  ? 358 ASP   A OD1 1 
ATOM   2444 O  OD2 . ASP   A 1 358 ? 130.338 89.020  95.057  1.00 96.28  ? 358 ASP   A OD2 1 
ATOM   2445 N  N   . ILE   A 1 359 ? 125.094 88.463  93.379  1.00 86.87  ? 359 ILE   A N   1 
ATOM   2446 C  CA  . ILE   A 1 359 ? 123.672 88.795  93.367  1.00 86.87  ? 359 ILE   A CA  1 
ATOM   2447 C  C   . ILE   A 1 359 ? 123.403 90.035  94.209  1.00 86.87  ? 359 ILE   A C   1 
ATOM   2448 O  O   . ILE   A 1 359 ? 122.590 90.890  93.840  1.00 86.87  ? 359 ILE   A O   1 
ATOM   2449 C  CB  . ILE   A 1 359 ? 122.835 87.591  93.845  1.00 86.87  ? 359 ILE   A CB  1 
ATOM   2450 C  CG1 . ILE   A 1 359 ? 122.992 86.401  92.892  1.00 86.87  ? 359 ILE   A CG1 1 
ATOM   2451 C  CG2 . ILE   A 1 359 ? 121.367 87.970  93.972  1.00 86.87  ? 359 ILE   A CG2 1 
ATOM   2452 C  CD1 . ILE   A 1 359 ? 124.138 85.464  93.231  1.00 86.87  ? 359 ILE   A CD1 1 
ATOM   2453 N  N   . ALA   A 1 360 ? 124.092 90.164  95.343  1.00 86.60  ? 360 ALA   A N   1 
ATOM   2454 C  CA  . ALA   A 1 360 ? 123.873 91.299  96.231  1.00 86.60  ? 360 ALA   A CA  1 
ATOM   2455 C  C   . ALA   A 1 360 ? 124.401 92.612  95.667  1.00 86.60  ? 360 ALA   A C   1 
ATOM   2456 O  O   . ALA   A 1 360 ? 124.126 93.666  96.250  1.00 86.60  ? 360 ALA   A O   1 
ATOM   2457 C  CB  . ALA   A 1 360 ? 124.514 91.030  97.593  1.00 86.60  ? 360 ALA   A CB  1 
ATOM   2458 N  N   . ASP   A 1 361 ? 125.143 92.581  94.560  1.00 90.77  ? 361 ASP   A N   1 
ATOM   2459 C  CA  . ASP   A 1 361 ? 125.762 93.780  94.012  1.00 90.77  ? 361 ASP   A CA  1 
ATOM   2460 C  C   . ASP   A 1 361 ? 125.273 94.152  92.618  1.00 90.77  ? 361 ASP   A C   1 
ATOM   2461 O  O   . ASP   A 1 361 ? 125.779 95.124  92.046  1.00 90.77  ? 361 ASP   A O   1 
ATOM   2462 C  CB  . ASP   A 1 361 ? 127.288 93.617  93.982  1.00 90.77  ? 361 ASP   A CB  1 
ATOM   2463 C  CG  . ASP   A 1 361 ? 127.852 93.176  95.317  1.00 90.77  ? 361 ASP   A CG  1 
ATOM   2464 O  OD1 . ASP   A 1 361 ? 127.363 93.659  96.359  1.00 90.77  ? 361 ASP   A OD1 1 
ATOM   2465 O  OD2 . ASP   A 1 361 ? 128.784 92.345  95.325  1.00 90.77  ? 361 ASP   A OD2 1 
ATOM   2466 N  N   . VAL   A 1 362 ? 124.314 93.417  92.050  1.00 86.34  ? 362 VAL   A N   1 
ATOM   2467 C  CA  . VAL   A 1 362 ? 123.882 93.709  90.685  1.00 86.34  ? 362 VAL   A CA  1 
ATOM   2468 C  C   . VAL   A 1 362 ? 123.113 95.024  90.628  1.00 86.34  ? 362 VAL   A C   1 
ATOM   2469 O  O   . VAL   A 1 362 ? 123.318 95.838  89.720  1.00 86.34  ? 362 VAL   A O   1 
ATOM   2470 C  CB  . VAL   A 1 362 ? 123.062 92.537  90.114  1.00 86.34  ? 362 VAL   A CB  1 
ATOM   2471 C  CG1 . VAL   A 1 362 ? 123.934 91.311  89.991  1.00 86.34  ? 362 VAL   A CG1 1 
ATOM   2472 C  CG2 . VAL   A 1 362 ? 121.849 92.234  90.983  1.00 86.34  ? 362 VAL   A CG2 1 
ATOM   2473 N  N   . ALA   A 1 363 ? 122.225 95.258  91.588  1.00 86.02  ? 363 ALA   A N   1 
ATOM   2474 C  CA  . ALA   A 1 363 ? 121.433 96.477  91.623  1.00 86.02  ? 363 ALA   A CA  1 
ATOM   2475 C  C   . ALA   A 1 363 ? 122.148 97.510  92.496  1.00 86.02  ? 363 ALA   A C   1 
ATOM   2476 O  O   . ALA   A 1 363 ? 123.306 97.323  92.877  1.00 86.02  ? 363 ALA   A O   1 
ATOM   2477 C  CB  . ALA   A 1 363 ? 120.016 96.164  92.110  1.00 86.02  ? 363 ALA   A CB  1 
ATOM   2478 N  N   . GLU   A 1 364 ? 121.470 98.608  92.821  1.00 85.28  ? 364 GLU   A N   1 
ATOM   2479 C  CA  . GLU   A 1 364 ? 122.032 99.650  93.667  1.00 85.28  ? 364 GLU   A CA  1 
ATOM   2480 C  C   . GLU   A 1 364 ? 121.699 99.453  95.139  1.00 85.28  ? 364 GLU   A C   1 
ATOM   2481 O  O   . GLU   A 1 364 ? 122.081 100.288 95.965  1.00 85.28  ? 364 GLU   A O   1 
ATOM   2482 C  CB  . GLU   A 1 364 ? 121.543 101.025 93.208  1.00 85.28  ? 364 GLU   A CB  1 
ATOM   2483 C  CG  . GLU   A 1 364 ? 122.333 101.618 92.058  1.00 85.28  ? 364 GLU   A CG  1 
ATOM   2484 C  CD  . GLU   A 1 364 ? 121.740 102.920 91.562  1.00 85.28  ? 364 GLU   A CD  1 
ATOM   2485 O  OE1 . GLU   A 1 364 ? 120.822 103.446 92.227  1.00 85.28  ? 364 GLU   A OE1 1 
ATOM   2486 O  OE2 . GLU   A 1 364 ? 122.191 103.420 90.510  1.00 85.28  ? 364 GLU   A OE2 1 
ATOM   2487 N  N   . SER   A 1 365 ? 120.993 98.375  95.483  1.00 78.72  ? 365 SER   A N   1 
ATOM   2488 C  CA  . SER   A 1 365 ? 120.537 98.104  96.846  1.00 78.72  ? 365 SER   A CA  1 
ATOM   2489 C  C   . SER   A 1 365 ? 119.668 99.229  97.396  1.00 78.72  ? 365 SER   A C   1 
ATOM   2490 O  O   . SER   A 1 365 ? 119.507 99.355  98.614  1.00 78.72  ? 365 SER   A O   1 
ATOM   2491 C  CB  . SER   A 1 365 ? 121.718 97.838  97.788  1.00 78.72  ? 365 SER   A CB  1 
ATOM   2492 O  OG  . SER   A 1 365 ? 121.268 97.402  99.058  1.00 78.72  ? 365 SER   A OG  1 
ATOM   2493 N  N   . GLY   A 1 366 ? 119.100 100.049 96.516  1.00 77.87  ? 366 GLY   A N   1 
ATOM   2494 C  CA  . GLY   A 1 366 ? 118.297 101.175 96.922  1.00 77.87  ? 366 GLY   A CA  1 
ATOM   2495 C  C   . GLY   A 1 366 ? 116.892 101.105 96.359  1.00 77.87  ? 366 GLY   A C   1 
ATOM   2496 O  O   . GLY   A 1 366 ? 116.447 100.065 95.865  1.00 77.87  ? 366 GLY   A O   1 
ATOM   2497 N  N   . PRO   A 1 367 ? 116.167 102.223 96.413  1.00 70.83  ? 367 PRO   A N   1 
ATOM   2498 C  CA  . PRO   A 1 367 ? 114.773 102.240 95.957  1.00 70.83  ? 367 PRO   A CA  1 
ATOM   2499 C  C   . PRO   A 1 367 ? 114.597 102.160 94.449  1.00 70.83  ? 367 PRO   A C   1 
ATOM   2500 O  O   . PRO   A 1 367 ? 113.458 102.222 93.977  1.00 70.83  ? 367 PRO   A O   1 
ATOM   2501 C  CB  . PRO   A 1 367 ? 114.266 103.586 96.493  1.00 70.83  ? 367 PRO   A CB  1 
ATOM   2502 C  CG  . PRO   A 1 367 ? 115.470 104.447 96.523  1.00 70.83  ? 367 PRO   A CG  1 
ATOM   2503 C  CD  . PRO   A 1 367 ? 116.624 103.548 96.863  1.00 70.83  ? 367 PRO   A CD  1 
ATOM   2504 N  N   . GLY   A 1 368 ? 115.675 102.022 93.687  1.00 73.11  ? 368 GLY   A N   1 
ATOM   2505 C  CA  . GLY   A 1 368 ? 115.608 101.881 92.249  1.00 73.11  ? 368 GLY   A CA  1 
ATOM   2506 C  C   . GLY   A 1 368 ? 115.619 100.455 91.747  1.00 73.11  ? 368 GLY   A C   1 
ATOM   2507 O  O   . GLY   A 1 368 ? 115.942 100.233 90.574  1.00 73.11  ? 368 GLY   A O   1 
ATOM   2508 N  N   . LEU   A 1 369 ? 115.286 99.480  92.595  1.00 73.96  ? 369 LEU   A N   1 
ATOM   2509 C  CA  . LEU   A 1 369 ? 115.367 98.077  92.206  1.00 73.96  ? 369 LEU   A CA  1 
ATOM   2510 C  C   . LEU   A 1 369 ? 114.421 97.758  91.052  1.00 73.96  ? 369 LEU   A C   1 
ATOM   2511 O  O   . LEU   A 1 369 ? 114.795 97.075  90.093  1.00 73.96  ? 369 LEU   A O   1 
ATOM   2512 C  CB  . LEU   A 1 369 ? 115.059 97.190  93.412  1.00 73.96  ? 369 LEU   A CB  1 
ATOM   2513 C  CG  . LEU   A 1 369 ? 115.172 95.690  93.156  1.00 73.96  ? 369 LEU   A CG  1 
ATOM   2514 C  CD1 . LEU   A 1 369 ? 116.595 95.336  92.783  1.00 73.96  ? 369 LEU   A CD1 1 
ATOM   2515 C  CD2 . LEU   A 1 369 ? 114.725 94.903  94.373  1.00 73.96  ? 369 LEU   A CD2 1 
ATOM   2516 N  N   . ALA   A 1 370 ? 113.181 98.243  91.138  1.00 75.84  ? 370 ALA   A N   1 
ATOM   2517 C  CA  . ALA   A 1 370 ? 112.190 97.938  90.110  1.00 75.84  ? 370 ALA   A CA  1 
ATOM   2518 C  C   . ALA   A 1 370 ? 112.585 98.518  88.759  1.00 75.84  ? 370 ALA   A C   1 
ATOM   2519 O  O   . ALA   A 1 370 ? 112.536 97.827  87.734  1.00 75.84  ? 370 ALA   A O   1 
ATOM   2520 C  CB  . ALA   A 1 370 ? 110.821 98.469  90.537  1.00 75.84  ? 370 ALA   A CB  1 
ATOM   2521 N  N   . PHE   A 1 371 ? 112.989 99.786  88.738  1.00 74.45  ? 371 PHE   A N   1 
ATOM   2522 C  CA  . PHE   A 1 371 ? 113.299 100.478 87.495  1.00 74.45  ? 371 PHE   A CA  1 
ATOM   2523 C  C   . PHE   A 1 371 ? 114.624 100.044 86.888  1.00 74.45  ? 371 PHE   A C   1 
ATOM   2524 O  O   . PHE   A 1 371 ? 114.944 100.466 85.771  1.00 74.45  ? 371 PHE   A O   1 
ATOM   2525 C  CB  . PHE   A 1 371 ? 113.286 101.988 87.734  1.00 74.45  ? 371 PHE   A CB  1 
ATOM   2526 C  CG  . PHE   A 1 371 ? 111.998 102.488 88.323  1.00 74.45  ? 371 PHE   A CG  1 
ATOM   2527 C  CD1 . PHE   A 1 371 ? 110.966 102.909 87.504  1.00 74.45  ? 371 PHE   A CD1 1 
ATOM   2528 C  CD2 . PHE   A 1 371 ? 111.810 102.515 89.693  1.00 74.45  ? 371 PHE   A CD2 1 
ATOM   2529 C  CE1 . PHE   A 1 371 ? 109.778 103.360 88.040  1.00 74.45  ? 371 PHE   A CE1 1 
ATOM   2530 C  CE2 . PHE   A 1 371 ? 110.622 102.962 90.234  1.00 74.45  ? 371 PHE   A CE2 1 
ATOM   2531 C  CZ  . PHE   A 1 371 ? 109.605 103.385 89.407  1.00 74.45  ? 371 PHE   A CZ  1 
ATOM   2532 N  N   . ILE   A 1 372 ? 115.400 99.223  87.593  1.00 78.29  ? 372 ILE   A N   1 
ATOM   2533 C  CA  . ILE   A 1 372 ? 116.593 98.599  87.031  1.00 78.29  ? 372 ILE   A CA  1 
ATOM   2534 C  C   . ILE   A 1 372 ? 116.366 97.135  86.684  1.00 78.29  ? 372 ILE   A C   1 
ATOM   2535 O  O   . ILE   A 1 372 ? 117.041 96.614  85.780  1.00 78.29  ? 372 ILE   A O   1 
ATOM   2536 C  CB  . ILE   A 1 372 ? 117.801 98.749  87.982  1.00 78.29  ? 372 ILE   A CB  1 
ATOM   2537 C  CG1 . ILE   A 1 372 ? 118.081 100.229 88.242  1.00 78.29  ? 372 ILE   A CG1 1 
ATOM   2538 C  CG2 . ILE   A 1 372 ? 119.053 98.108  87.405  1.00 78.29  ? 372 ILE   A CG2 1 
ATOM   2539 C  CD1 . ILE   A 1 372 ? 119.052 100.476 89.369  1.00 78.29  ? 372 ILE   A CD1 1 
ATOM   2540 N  N   . ALA   A 1 373 ? 115.409 96.469  87.331  1.00 79.67  ? 373 ALA   A N   1 
ATOM   2541 C  CA  . ALA   A 1 373 ? 115.128 95.061  87.068  1.00 79.67  ? 373 ALA   A CA  1 
ATOM   2542 C  C   . ALA   A 1 373 ? 114.161 94.877  85.899  1.00 79.67  ? 373 ALA   A C   1 
ATOM   2543 O  O   . ALA   A 1 373 ? 114.431 94.094  84.983  1.00 79.67  ? 373 ALA   A O   1 
ATOM   2544 C  CB  . ALA   A 1 373 ? 114.572 94.394  88.331  1.00 79.67  ? 373 ALA   A CB  1 
ATOM   2545 N  N   . TYR   A 1 374 ? 113.031 95.586  85.924  1.00 82.59  ? 374 TYR   A N   1 
ATOM   2546 C  CA  . TYR   A 1 374 ? 112.017 95.409  84.885  1.00 82.59  ? 374 TYR   A CA  1 
ATOM   2547 C  C   . TYR   A 1 374 ? 112.527 95.698  83.477  1.00 82.59  ? 374 TYR   A C   1 
ATOM   2548 O  O   . TYR   A 1 374 ? 112.249 94.890  82.571  1.00 82.59  ? 374 TYR   A O   1 
ATOM   2549 C  CB  . TYR   A 1 374 ? 110.795 96.276  85.205  1.00 82.59  ? 374 TYR   A CB  1 
ATOM   2550 C  CG  . TYR   A 1 374 ? 110.011 95.844  86.420  1.00 82.59  ? 374 TYR   A CG  1 
ATOM   2551 C  CD1 . TYR   A 1 374 ? 109.561 94.539  86.556  1.00 82.59  ? 374 TYR   A CD1 1 
ATOM   2552 C  CD2 . TYR   A 1 374 ? 109.696 96.753  87.421  1.00 82.59  ? 374 TYR   A CD2 1 
ATOM   2553 C  CE1 . TYR   A 1 374 ? 108.831 94.149  87.664  1.00 82.59  ? 374 TYR   A CE1 1 
ATOM   2554 C  CE2 . TYR   A 1 374 ? 108.968 96.374  88.527  1.00 82.59  ? 374 TYR   A CE2 1 
ATOM   2555 C  CZ  . TYR   A 1 374 ? 108.539 95.074  88.645  1.00 82.59  ? 374 TYR   A CZ  1 
ATOM   2556 O  OH  . TYR   A 1 374 ? 107.813 94.706  89.752  1.00 82.59  ? 374 TYR   A OH  1 
ATOM   2557 N  N   . PRO   A 1 375 ? 113.225 96.811  83.203  1.00 82.89  ? 375 PRO   A N   1 
ATOM   2558 C  CA  . PRO   A 1 375 ? 113.670 97.052  81.819  1.00 82.89  ? 375 PRO   A CA  1 
ATOM   2559 C  C   . PRO   A 1 375 ? 114.549 95.949  81.262  1.00 82.89  ? 375 PRO   A C   1 
ATOM   2560 O  O   . PRO   A 1 375 ? 114.418 95.594  80.084  1.00 82.89  ? 375 PRO   A O   1 
ATOM   2561 C  CB  . PRO   A 1 375 ? 114.427 98.382  81.926  1.00 82.89  ? 375 PRO   A CB  1 
ATOM   2562 C  CG  . PRO   A 1 375 ? 113.823 99.057  83.093  1.00 82.89  ? 375 PRO   A CG  1 
ATOM   2563 C  CD  . PRO   A 1 375 ? 113.539 97.962  84.070  1.00 82.89  ? 375 PRO   A CD  1 
ATOM   2564 N  N   . LYS   A 1 376 ? 115.439 95.385  82.081  1.00 81.66  ? 376 LYS   A N   1 
ATOM   2565 C  CA  . LYS   A 1 376 ? 116.286 94.301  81.604  1.00 81.66  ? 376 LYS   A CA  1 
ATOM   2566 C  C   . LYS   A 1 376 ? 115.486 93.048  81.281  1.00 81.66  ? 376 LYS   A C   1 
ATOM   2567 O  O   . LYS   A 1 376 ? 115.885 92.282  80.398  1.00 81.66  ? 376 LYS   A O   1 
ATOM   2568 C  CB  . LYS   A 1 376 ? 117.367 93.983  82.636  1.00 81.66  ? 376 LYS   A CB  1 
ATOM   2569 C  CG  . LYS   A 1 376 ? 118.462 93.075  82.112  1.00 81.66  ? 376 LYS   A CG  1 
ATOM   2570 C  CD  . LYS   A 1 376 ? 119.034 93.600  80.809  1.00 81.66  ? 376 LYS   A CD  1 
ATOM   2571 C  CE  . LYS   A 1 376 ? 119.869 92.539  80.116  1.00 81.66  ? 376 LYS   A CE  1 
ATOM   2572 N  NZ  . LYS   A 1 376 ? 121.084 92.195  80.901  1.00 81.66  ? 376 LYS   A NZ  1 
ATOM   2573 N  N   . ALA   A 1 377 ? 114.368 92.824  81.971  1.00 87.19  ? 377 ALA   A N   1 
ATOM   2574 C  CA  . ALA   A 1 377 ? 113.519 91.680  81.660  1.00 87.19  ? 377 ALA   A CA  1 
ATOM   2575 C  C   . ALA   A 1 377 ? 112.704 91.920  80.394  1.00 87.19  ? 377 ALA   A C   1 
ATOM   2576 O  O   . ALA   A 1 377 ? 112.537 91.011  79.574  1.00 87.19  ? 377 ALA   A O   1 
ATOM   2577 C  CB  . ALA   A 1 377 ? 112.598 91.371  82.841  1.00 87.19  ? 377 ALA   A CB  1 
ATOM   2578 N  N   . VAL   A 1 378 ? 112.188 93.140  80.217  1.00 86.02  ? 378 VAL   A N   1 
ATOM   2579 C  CA  . VAL   A 1 378 ? 111.332 93.422  79.069  1.00 86.02  ? 378 VAL   A CA  1 
ATOM   2580 C  C   . VAL   A 1 378 ? 112.111 93.692  77.793  1.00 86.02  ? 378 VAL   A C   1 
ATOM   2581 O  O   . VAL   A 1 378 ? 111.521 93.661  76.707  1.00 86.02  ? 378 VAL   A O   1 
ATOM   2582 C  CB  . VAL   A 1 378 ? 110.397 94.618  79.344  1.00 86.02  ? 378 VAL   A CB  1 
ATOM   2583 C  CG1 . VAL   A 1 378 ? 109.595 94.388  80.616  1.00 86.02  ? 378 VAL   A CG1 1 
ATOM   2584 C  CG2 . VAL   A 1 378 ? 111.190 95.911  79.417  1.00 86.02  ? 378 VAL   A CG2 1 
ATOM   2585 N  N   . THR   A 1 379 ? 113.415 93.965  77.885  1.00 88.37  ? 379 THR   A N   1 
ATOM   2586 C  CA  . THR   A 1 379 ? 114.191 94.204  76.674  1.00 88.37  ? 379 THR   A CA  1 
ATOM   2587 C  C   . THR   A 1 379 ? 114.345 92.949  75.820  1.00 88.37  ? 379 THR   A C   1 
ATOM   2588 O  O   . THR   A 1 379 ? 114.278 93.043  74.590  1.00 88.37  ? 379 THR   A O   1 
ATOM   2589 C  CB  . THR   A 1 379 ? 115.567 94.766  77.034  1.00 88.37  ? 379 THR   A CB  1 
ATOM   2590 O  OG1 . THR   A 1 379 ? 115.426 95.734  78.081  1.00 88.37  ? 379 THR   A OG1 1 
ATOM   2591 C  CG2 . THR   A 1 379 ? 116.200 95.437  75.827  1.00 88.37  ? 379 THR   A CG2 1 
ATOM   2592 N  N   . MET   A 1 380 ? 114.548 91.784  76.436  1.00 93.66  ? 380 MET   A N   1 
ATOM   2593 C  CA  . MET   A 1 380 ? 114.630 90.519  75.713  1.00 93.66  ? 380 MET   A CA  1 
ATOM   2594 C  C   . MET   A 1 380 ? 113.275 89.965  75.293  1.00 93.66  ? 380 MET   A C   1 
ATOM   2595 O  O   . MET   A 1 380 ? 113.171 89.370  74.215  1.00 93.66  ? 380 MET   A O   1 
ATOM   2596 C  CB  . MET   A 1 380 ? 115.351 89.463  76.562  1.00 93.66  ? 380 MET   A CB  1 
ATOM   2597 C  CG  . MET   A 1 380 ? 116.856 89.660  76.810  1.00 93.66  ? 380 MET   A CG  1 
ATOM   2598 S  SD  . MET   A 1 380 ? 117.848 90.389  75.482  1.00 93.66  ? 380 MET   A SD  1 
ATOM   2599 C  CE  . MET   A 1 380 ? 117.712 92.147  75.792  1.00 93.66  ? 380 MET   A CE  1 
ATOM   2600 N  N   . MET   A 1 381 ? 112.246 90.138  76.114  1.00 89.95  ? 381 MET   A N   1 
ATOM   2601 C  CA  . MET   A 1 381 ? 110.947 89.556  75.814  1.00 89.95  ? 381 MET   A CA  1 
ATOM   2602 C  C   . MET   A 1 381 ? 110.304 90.290  74.636  1.00 89.95  ? 381 MET   A C   1 
ATOM   2603 O  O   . MET   A 1 381 ? 110.307 91.526  74.597  1.00 89.95  ? 381 MET   A O   1 
ATOM   2604 C  CB  . MET   A 1 381 ? 110.067 89.599  77.068  1.00 89.95  ? 381 MET   A CB  1 
ATOM   2605 C  CG  . MET   A 1 381 ? 108.606 89.225  76.903  1.00 89.95  ? 381 MET   A CG  1 
ATOM   2606 S  SD  . MET   A 1 381 ? 107.575 90.600  76.380  1.00 89.95  ? 381 MET   A SD  1 
ATOM   2607 C  CE  . MET   A 1 381 ? 106.797 91.031  77.935  1.00 89.95  ? 381 MET   A CE  1 
ATOM   2608 N  N   . PRO   A 1 382 ? 109.745 89.563  73.664  1.00 96.51  ? 382 PRO   A N   1 
ATOM   2609 C  CA  . PRO   A 1 382 ? 109.390 90.179  72.377  1.00 96.51  ? 382 PRO   A CA  1 
ATOM   2610 C  C   . PRO   A 1 382 ? 108.303 91.238  72.498  1.00 96.51  ? 382 PRO   A C   1 
ATOM   2611 O  O   . PRO   A 1 382 ? 107.474 91.214  73.409  1.00 96.51  ? 382 PRO   A O   1 
ATOM   2612 C  CB  . PRO   A 1 382 ? 108.908 88.988  71.539  1.00 96.51  ? 382 PRO   A CB  1 
ATOM   2613 C  CG  . PRO   A 1 382 ? 109.554 87.798  72.171  1.00 96.51  ? 382 PRO   A CG  1 
ATOM   2614 C  CD  . PRO   A 1 382 ? 109.564 88.102  73.639  1.00 96.51  ? 382 PRO   A CD  1 
ATOM   2615 N  N   . LEU   A 1 383 ? 108.320 92.175  71.540  1.00 93.97  ? 383 LEU   A N   1 
ATOM   2616 C  CA  . LEU   A 1 383 ? 107.425 93.327  71.463  1.00 93.97  ? 383 LEU   A CA  1 
ATOM   2617 C  C   . LEU   A 1 383 ? 107.582 94.188  72.712  1.00 93.97  ? 383 LEU   A C   1 
ATOM   2618 O  O   . LEU   A 1 383 ? 106.648 94.299  73.517  1.00 93.97  ? 383 LEU   A O   1 
ATOM   2619 C  CB  . LEU   A 1 383 ? 105.973 92.879  71.284  1.00 93.97  ? 383 LEU   A CB  1 
ATOM   2620 C  CG  . LEU   A 1 383 ? 104.947 93.953  70.913  1.00 93.97  ? 383 LEU   A CG  1 
ATOM   2621 C  CD1 . LEU   A 1 383 ? 105.050 94.308  69.439  1.00 93.97  ? 383 LEU   A CD1 1 
ATOM   2622 C  CD2 . LEU   A 1 383 ? 103.545 93.485  71.258  1.00 93.97  ? 383 LEU   A CD2 1 
ATOM   2623 N  N   . PRO   A 1 384 ? 108.753 94.800  72.914  1.00 89.58  ? 384 PRO   A N   1 
ATOM   2624 C  CA  . PRO   A 1 384 ? 108.985 95.536  74.169  1.00 89.58  ? 384 PRO   A CA  1 
ATOM   2625 C  C   . PRO   A 1 384 ? 108.045 96.710  74.396  1.00 89.58  ? 384 PRO   A C   1 
ATOM   2626 O  O   . PRO   A 1 384 ? 107.670 96.980  75.542  1.00 89.58  ? 384 PRO   A O   1 
ATOM   2627 C  CB  . PRO   A 1 384 ? 110.445 95.994  74.026  1.00 89.58  ? 384 PRO   A CB  1 
ATOM   2628 C  CG  . PRO   A 1 384 ? 111.043 95.068  73.010  1.00 89.58  ? 384 PRO   A CG  1 
ATOM   2629 C  CD  . PRO   A 1 384 ? 109.937 94.826  72.041  1.00 89.58  ? 384 PRO   A CD  1 
ATOM   2630 N  N   . THR   A 1 385 ? 107.649 97.416  73.334  1.00 88.22  ? 385 THR   A N   1 
ATOM   2631 C  CA  . THR   A 1 385 ? 106.964 98.693  73.514  1.00 88.22  ? 385 THR   A CA  1 
ATOM   2632 C  C   . THR   A 1 385 ? 105.568 98.516  74.102  1.00 88.22  ? 385 THR   A C   1 
ATOM   2633 O  O   . THR   A 1 385 ? 105.209 99.189  75.076  1.00 88.22  ? 385 THR   A O   1 
ATOM   2634 C  CB  . THR   A 1 385 ? 106.889 99.438  72.181  1.00 88.22  ? 385 THR   A CB  1 
ATOM   2635 O  OG1 . THR   A 1 385 ? 108.210 99.612  71.655  1.00 88.22  ? 385 THR   A OG1 1 
ATOM   2636 C  CG2 . THR   A 1 385 ? 106.243 100.802 72.371  1.00 88.22  ? 385 THR   A CG2 1 
ATOM   2637 N  N   . PHE   A 1 386 ? 104.764 97.620  73.523  1.00 86.60  ? 386 PHE   A N   1 
ATOM   2638 C  CA  . PHE   A 1 386 ? 103.388 97.457  73.986  1.00 86.60  ? 386 PHE   A CA  1 
ATOM   2639 C  C   . PHE   A 1 386 ? 103.348 96.928  75.413  1.00 86.60  ? 386 PHE   A C   1 
ATOM   2640 O  O   . PHE   A 1 386 ? 102.571 97.412  76.248  1.00 86.60  ? 386 PHE   A O   1 
ATOM   2641 C  CB  . PHE   A 1 386 ? 102.631 96.522  73.041  1.00 86.60  ? 386 PHE   A CB  1 
ATOM   2642 C  CG  . PHE   A 1 386 ? 101.175 96.365  73.375  1.00 86.60  ? 386 PHE   A CG  1 
ATOM   2643 C  CD1 . PHE   A 1 386 ? 100.387 97.473  73.640  1.00 86.60  ? 386 PHE   A CD1 1 
ATOM   2644 C  CD2 . PHE   A 1 386 ? 100.593 95.110  73.415  1.00 86.60  ? 386 PHE   A CD2 1 
ATOM   2645 C  CE1 . PHE   A 1 386 ? 99.047  97.331  73.943  1.00 86.60  ? 386 PHE   A CE1 1 
ATOM   2646 C  CE2 . PHE   A 1 386 ? 99.254  94.961  73.718  1.00 86.60  ? 386 PHE   A CE2 1 
ATOM   2647 C  CZ  . PHE   A 1 386 ? 98.479  96.073  73.982  1.00 86.60  ? 386 PHE   A CZ  1 
ATOM   2648 N  N   . TRP   A 1 387 ? 104.189 95.938  75.711  1.00 87.27  ? 387 TRP   A N   1 
ATOM   2649 C  CA  . TRP   A 1 387 ? 104.226 95.382  77.057  1.00 87.27  ? 387 TRP   A CA  1 
ATOM   2650 C  C   . TRP   A 1 387 ? 104.764 96.394  78.059  1.00 87.27  ? 387 TRP   A C   1 
ATOM   2651 O  O   . TRP   A 1 387 ? 104.307 96.435  79.204  1.00 87.27  ? 387 TRP   A O   1 
ATOM   2652 C  CB  . TRP   A 1 387 ? 105.051 94.097  77.063  1.00 87.27  ? 387 TRP   A CB  1 
ATOM   2653 C  CG  . TRP   A 1 387 ? 104.394 92.970  76.308  1.00 87.27  ? 387 TRP   A CG  1 
ATOM   2654 C  CD1 . TRP   A 1 387 ? 104.937 92.238  75.294  1.00 87.27  ? 387 TRP   A CD1 1 
ATOM   2655 C  CD2 . TRP   A 1 387 ? 103.080 92.435  76.528  1.00 87.27  ? 387 TRP   A CD2 1 
ATOM   2656 N  NE1 . TRP   A 1 387 ? 104.042 91.291  74.859  1.00 87.27  ? 387 TRP   A NE1 1 
ATOM   2657 C  CE2 . TRP   A 1 387 ? 102.895 91.390  75.602  1.00 87.27  ? 387 TRP   A CE2 1 
ATOM   2658 C  CE3 . TRP   A 1 387 ? 102.042 92.742  77.414  1.00 87.27  ? 387 TRP   A CE3 1 
ATOM   2659 C  CZ2 . TRP   A 1 387 ? 101.716 90.652  75.536  1.00 87.27  ? 387 TRP   A CZ2 1 
ATOM   2660 C  CZ3 . TRP   A 1 387 ? 100.874 92.009  77.346  1.00 87.27  ? 387 TRP   A CZ3 1 
ATOM   2661 C  CH2 . TRP   A 1 387 ? 100.720 90.976  76.415  1.00 87.27  ? 387 TRP   A CH2 1 
ATOM   2662 N  N   . SER   A 1 388 ? 105.721 97.229  77.647  1.00 81.17  ? 388 SER   A N   1 
ATOM   2663 C  CA  . SER   A 1 388 ? 106.208 98.289  78.525  1.00 81.17  ? 388 SER   A CA  1 
ATOM   2664 C  C   . SER   A 1 388 ? 105.104 99.291  78.840  1.00 81.17  ? 388 SER   A C   1 
ATOM   2665 O  O   . SER   A 1 388 ? 104.937 99.713  79.990  1.00 81.17  ? 388 SER   A O   1 
ATOM   2666 C  CB  . SER   A 1 388 ? 107.405 98.991  77.880  1.00 81.17  ? 388 SER   A CB  1 
ATOM   2667 O  OG  . SER   A 1 388 ? 108.490 98.098  77.706  1.00 81.17  ? 388 SER   A OG  1 
ATOM   2668 N  N   . ILE   A 1 389 ? 104.335 99.681  77.821  1.00 80.13  ? 389 ILE   A N   1 
ATOM   2669 C  CA  . ILE   A 1 389 ? 103.235 100.621 78.031  1.00 80.13  ? 389 ILE   A CA  1 
ATOM   2670 C  C   . ILE   A 1 389 ? 102.215 100.031 78.996  1.00 80.13  ? 389 ILE   A C   1 
ATOM   2671 O  O   . ILE   A 1 389 ? 101.768 100.693 79.942  1.00 80.13  ? 389 ILE   A O   1 
ATOM   2672 C  CB  . ILE   A 1 389 ? 102.580 100.996 76.689  1.00 80.13  ? 389 ILE   A CB  1 
ATOM   2673 C  CG1 . ILE   A 1 389 ? 103.577 101.717 75.783  1.00 80.13  ? 389 ILE   A CG1 1 
ATOM   2674 C  CG2 . ILE   A 1 389 ? 101.350 101.860 76.918  1.00 80.13  ? 389 ILE   A CG2 1 
ATOM   2675 C  CD1 . ILE   A 1 389 ? 103.092 101.886 74.360  1.00 80.13  ? 389 ILE   A CD1 1 
ATOM   2676 N  N   . LEU   A 1 390 ? 101.835 98.770  78.769  1.00 83.99  ? 390 LEU   A N   1 
ATOM   2677 C  CA  . LEU   A 1 390 ? 100.860 98.123  79.644  1.00 83.99  ? 390 LEU   A CA  1 
ATOM   2678 C  C   . LEU   A 1 390 ? 101.396 97.989  81.065  1.00 83.99  ? 390 LEU   A C   1 
ATOM   2679 O  O   . LEU   A 1 390 ? 100.670 98.220  82.039  1.00 83.99  ? 390 LEU   A O   1 
ATOM   2680 C  CB  . LEU   A 1 390 ? 100.482 96.753  79.083  1.00 83.99  ? 390 LEU   A CB  1 
ATOM   2681 C  CG  . LEU   A 1 390 ? 99.506  96.747  77.906  1.00 83.99  ? 390 LEU   A CG  1 
ATOM   2682 C  CD1 . LEU   A 1 390 ? 99.225  95.322  77.461  1.00 83.99  ? 390 LEU   A CD1 1 
ATOM   2683 C  CD2 . LEU   A 1 390 ? 98.216  97.462  78.272  1.00 83.99  ? 390 LEU   A CD2 1 
ATOM   2684 N  N   . PHE   A 1 391 ? 102.671 97.629  81.200  1.00 79.37  ? 391 PHE   A N   1 
ATOM   2685 C  CA  . PHE   A 1 391 ? 103.280 97.472  82.513  1.00 79.37  ? 391 PHE   A CA  1 
ATOM   2686 C  C   . PHE   A 1 391 ? 103.274 98.785  83.284  1.00 79.37  ? 391 PHE   A C   1 
ATOM   2687 O  O   . PHE   A 1 391 ? 102.901 98.830  84.462  1.00 79.37  ? 391 PHE   A O   1 
ATOM   2688 C  CB  . PHE   A 1 391 ? 104.705 96.952  82.340  1.00 79.37  ? 391 PHE   A CB  1 
ATOM   2689 C  CG  . PHE   A 1 391 ? 105.416 96.705  83.623  1.00 79.37  ? 391 PHE   A CG  1 
ATOM   2690 C  CD1 . PHE   A 1 391 ? 104.833 95.938  84.613  1.00 79.37  ? 391 PHE   A CD1 1 
ATOM   2691 C  CD2 . PHE   A 1 391 ? 106.664 97.248  83.847  1.00 79.37  ? 391 PHE   A CD2 1 
ATOM   2692 C  CE1 . PHE   A 1 391 ? 105.489 95.707  85.796  1.00 79.37  ? 391 PHE   A CE1 1 
ATOM   2693 C  CE2 . PHE   A 1 391 ? 107.319 97.025  85.030  1.00 79.37  ? 391 PHE   A CE2 1 
ATOM   2694 C  CZ  . PHE   A 1 391 ? 106.729 96.254  86.007  1.00 79.37  ? 391 PHE   A CZ  1 
ATOM   2695 N  N   . PHE   A 1 392 ? 103.678 99.874  82.627  1.00 74.42  ? 392 PHE   A N   1 
ATOM   2696 C  CA  . PHE   A 1 392 ? 103.745 101.150 83.326  1.00 74.42  ? 392 PHE   A CA  1 
ATOM   2697 C  C   . PHE   A 1 392 ? 102.358 101.711 83.611  1.00 74.42  ? 392 PHE   A C   1 
ATOM   2698 O  O   . PHE   A 1 392 ? 102.158 102.347 84.650  1.00 74.42  ? 392 PHE   A O   1 
ATOM   2699 C  CB  . PHE   A 1 392 ? 104.589 102.145 82.534  1.00 74.42  ? 392 PHE   A CB  1 
ATOM   2700 C  CG  . PHE   A 1 392 ? 106.066 101.899 82.648  1.00 74.42  ? 392 PHE   A CG  1 
ATOM   2701 C  CD1 . PHE   A 1 392 ? 106.700 101.990 83.874  1.00 74.42  ? 392 PHE   A CD1 1 
ATOM   2702 C  CD2 . PHE   A 1 392 ? 106.818 101.573 81.535  1.00 74.42  ? 392 PHE   A CD2 1 
ATOM   2703 C  CE1 . PHE   A 1 392 ? 108.056 101.760 83.987  1.00 74.42  ? 392 PHE   A CE1 1 
ATOM   2704 C  CE2 . PHE   A 1 392 ? 108.174 101.342 81.641  1.00 74.42  ? 392 PHE   A CE2 1 
ATOM   2705 C  CZ  . PHE   A 1 392 ? 108.794 101.436 82.868  1.00 74.42  ? 392 PHE   A CZ  1 
ATOM   2706 N  N   . ILE   A 1 393 ? 101.381 101.469 82.733  1.00 80.07  ? 393 ILE   A N   1 
ATOM   2707 C  CA  . ILE   A 1 393 ? 100.029 101.908 83.061  1.00 80.07  ? 393 ILE   A CA  1 
ATOM   2708 C  C   . ILE   A 1 393 ? 99.475  101.090 84.223  1.00 80.07  ? 393 ILE   A C   1 
ATOM   2709 O  O   . ILE   A 1 393 ? 98.703  101.604 85.035  1.00 80.07  ? 393 ILE   A O   1 
ATOM   2710 C  CB  . ILE   A 1 393 ? 99.111  101.861 81.822  1.00 80.07  ? 393 ILE   A CB  1 
ATOM   2711 C  CG1 . ILE   A 1 393 ? 97.897  102.768 82.026  1.00 80.07  ? 393 ILE   A CG1 1 
ATOM   2712 C  CG2 . ILE   A 1 393 ? 98.639  100.454 81.523  1.00 80.07  ? 393 ILE   A CG2 1 
ATOM   2713 C  CD1 . ILE   A 1 393 ? 97.070  102.968 80.777  1.00 80.07  ? 393 ILE   A CD1 1 
ATOM   2714 N  N   . MET   A 1 394 ? 99.878  99.822  84.344  1.00 81.24  ? 394 MET   A N   1 
ATOM   2715 C  CA  . MET   A 1 394 ? 99.470  99.015  85.493  1.00 81.24  ? 394 MET   A CA  1 
ATOM   2716 C  C   . MET   A 1 394 ? 100.098 99.532  86.786  1.00 81.24  ? 394 MET   A C   1 
ATOM   2717 O  O   . MET   A 1 394 ? 99.431  99.596  87.832  1.00 81.24  ? 394 MET   A O   1 
ATOM   2718 C  CB  . MET   A 1 394 ? 99.824  97.550  85.216  1.00 81.24  ? 394 MET   A CB  1 
ATOM   2719 C  CG  . MET   A 1 394 ? 99.424  96.529  86.268  1.00 81.24  ? 394 MET   A CG  1 
ATOM   2720 S  SD  . MET   A 1 394 ? 100.577 96.404  87.641  1.00 81.24  ? 394 MET   A SD  1 
ATOM   2721 C  CE  . MET   A 1 394 ? 101.954 95.574  86.848  1.00 81.24  ? 394 MET   A CE  1 
ATOM   2722 N  N   . LEU   A 1 395 ? 101.377 99.912  86.733  1.00 79.15  ? 395 LEU   A N   1 
ATOM   2723 C  CA  . LEU   A 1 395 ? 102.011 100.540 87.891  1.00 79.15  ? 395 LEU   A CA  1 
ATOM   2724 C  C   . LEU   A 1 395 ? 101.303 101.834 88.268  1.00 79.15  ? 395 LEU   A C   1 
ATOM   2725 O  O   . LEU   A 1 395 ? 101.084 102.115 89.453  1.00 79.15  ? 395 LEU   A O   1 
ATOM   2726 C  CB  . LEU   A 1 395 ? 103.490 100.809 87.614  1.00 79.15  ? 395 LEU   A CB  1 
ATOM   2727 C  CG  . LEU   A 1 395 ? 104.493 99.743  88.049  1.00 79.15  ? 395 LEU   A CG  1 
ATOM   2728 C  CD1 . LEU   A 1 395 ? 104.354 98.512  87.203  1.00 79.15  ? 395 LEU   A CD1 1 
ATOM   2729 C  CD2 . LEU   A 1 395 ? 105.907 100.290 87.970  1.00 79.15  ? 395 LEU   A CD2 1 
ATOM   2730 N  N   . LEU   A 1 396 ? 100.953 102.647 87.268  1.00 79.58  ? 396 LEU   A N   1 
ATOM   2731 C  CA  . LEU   A 1 396 ? 100.207 103.870 87.540  1.00 79.58  ? 396 LEU   A CA  1 
ATOM   2732 C  C   . LEU   A 1 396 ? 98.851  103.565 88.160  1.00 79.58  ? 396 LEU   A C   1 
ATOM   2733 O  O   . LEU   A 1 396 ? 98.404  104.281 89.059  1.00 79.58  ? 396 LEU   A O   1 
ATOM   2734 C  CB  . LEU   A 1 396 ? 100.048 104.702 86.267  1.00 79.58  ? 396 LEU   A CB  1 
ATOM   2735 C  CG  . LEU   A 1 396 ? 101.121 105.760 85.975  1.00 79.58  ? 396 LEU   A CG  1 
ATOM   2736 C  CD1 . LEU   A 1 396 ? 101.076 106.853 87.035  1.00 79.58  ? 396 LEU   A CD1 1 
ATOM   2737 C  CD2 . LEU   A 1 396 ? 102.517 105.168 85.894  1.00 79.58  ? 396 LEU   A CD2 1 
ATOM   2738 N  N   . LEU   A 1 397 ? 98.183  102.505 87.701  1.00 78.20  ? 397 LEU   A N   1 
ATOM   2739 C  CA  . LEU   A 1 397 ? 96.902  102.128 88.291  1.00 78.20  ? 397 LEU   A CA  1 
ATOM   2740 C  C   . LEU   A 1 397 ? 97.056  101.802 89.771  1.00 78.20  ? 397 LEU   A C   1 
ATOM   2741 O  O   . LEU   A 1 397 ? 96.307  102.316 90.613  1.00 78.20  ? 397 LEU   A O   1 
ATOM   2742 C  CB  . LEU   A 1 397 ? 96.305  100.937 87.541  1.00 78.20  ? 397 LEU   A CB  1 
ATOM   2743 C  CG  . LEU   A 1 397 ? 95.750  101.190 86.139  1.00 78.20  ? 397 LEU   A CG  1 
ATOM   2744 C  CD1 . LEU   A 1 397 ? 95.451  99.872  85.446  1.00 78.20  ? 397 LEU   A CD1 1 
ATOM   2745 C  CD2 . LEU   A 1 397 ? 94.512  102.068 86.193  1.00 78.20  ? 397 LEU   A CD2 1 
ATOM   2746 N  N   . LEU   A 1 398 ? 98.031  100.949 90.107  1.00 81.46  ? 398 LEU   A N   1 
ATOM   2747 C  CA  . LEU   A 1 398 ? 98.235  100.588 91.511  1.00 81.46  ? 398 LEU   A CA  1 
ATOM   2748 C  C   . LEU   A 1 398 ? 98.565  101.815 92.349  1.00 81.46  ? 398 LEU   A C   1 
ATOM   2749 O  O   . LEU   A 1 398 ? 97.937  102.069 93.391  1.00 81.46  ? 398 LEU   A O   1 
ATOM   2750 C  CB  . LEU   A 1 398 ? 99.352  99.555  91.657  1.00 81.46  ? 398 LEU   A CB  1 
ATOM   2751 C  CG  . LEU   A 1 398 ? 99.300  98.194  90.970  1.00 81.46  ? 398 LEU   A CG  1 
ATOM   2752 C  CD1 . LEU   A 1 398 ? 100.719 97.699  90.760  1.00 81.46  ? 398 LEU   A CD1 1 
ATOM   2753 C  CD2 . LEU   A 1 398 ? 98.498  97.204  91.792  1.00 81.46  ? 398 LEU   A CD2 1 
ATOM   2754 N  N   . GLY   A 1 399 ? 99.565  102.583 91.911  1.00 80.48  ? 399 GLY   A N   1 
ATOM   2755 C  CA  . GLY   A 1 399 ? 99.964  103.755 92.660  1.00 80.48  ? 399 GLY   A CA  1 
ATOM   2756 C  C   . GLY   A 1 399 ? 98.836  104.747 92.829  1.00 80.48  ? 399 GLY   A C   1 
ATOM   2757 O  O   . GLY   A 1 399 ? 98.664  105.311 93.908  1.00 80.48  ? 399 GLY   A O   1 
ATOM   2758 N  N   . LEU   A 1 400 ? 98.066  104.961 91.765  1.00 81.04  ? 400 LEU   A N   1 
ATOM   2759 C  CA  . LEU   A 1 400 ? 96.961  105.911 91.822  1.00 81.04  ? 400 LEU   A CA  1 
ATOM   2760 C  C   . LEU   A 1 400 ? 95.904  105.443 92.804  1.00 81.04  ? 400 LEU   A C   1 
ATOM   2761 O  O   . LEU   A 1 400 ? 95.450  106.225 93.631  1.00 81.04  ? 400 LEU   A O   1 
ATOM   2762 C  CB  . LEU   A 1 400 ? 96.335  106.131 90.444  1.00 81.04  ? 400 LEU   A CB  1 
ATOM   2763 C  CG  . LEU   A 1 400 ? 95.347  107.291 90.321  1.00 81.04  ? 400 LEU   A CG  1 
ATOM   2764 C  CD1 . LEU   A 1 400 ? 96.014  108.613 90.672  1.00 81.04  ? 400 LEU   A CD1 1 
ATOM   2765 C  CD2 . LEU   A 1 400 ? 94.749  107.340 88.924  1.00 81.04  ? 400 LEU   A CD2 1 
ATOM   2766 N  N   . ASP   A 1 401 ? 95.500  104.178 92.723  1.00 82.33  ? 401 ASP   A N   1 
ATOM   2767 C  CA  . ASP   A 1 401 ? 94.432  103.744 93.610  1.00 82.33  ? 401 ASP   A CA  1 
ATOM   2768 C  C   . ASP   A 1 401 ? 94.887  103.863 95.055  1.00 82.33  ? 401 ASP   A C   1 
ATOM   2769 O  O   . ASP   A 1 401 ? 94.152  104.369 95.891  1.00 82.33  ? 401 ASP   A O   1 
ATOM   2770 C  CB  . ASP   A 1 401 ? 93.835  102.360 93.252  1.00 82.33  ? 401 ASP   A CB  1 
ATOM   2771 C  CG  . ASP   A 1 401 ? 94.815  101.200 93.415  1.00 82.33  ? 401 ASP   A CG  1 
ATOM   2772 O  OD1 . ASP   A 1 401 ? 95.338  100.971 94.525  1.00 82.33  ? 401 ASP   A OD1 1 
ATOM   2773 O  OD2 . ASP   A 1 401 ? 95.014  100.465 92.428  1.00 82.33  ? 401 ASP   A OD2 1 
ATOM   2774 N  N   . SER   A 1 402 ? 96.124  103.470 95.334  1.00 78.03  ? 402 SER   A N   1 
ATOM   2775 C  CA  . SER   A 1 402 ? 96.645  103.606 96.681  1.00 78.03  ? 402 SER   A CA  1 
ATOM   2776 C  C   . SER   A 1 402 ? 96.699  105.076 97.055  1.00 78.03  ? 402 SER   A C   1 
ATOM   2777 O  O   . SER   A 1 402 ? 96.320  105.447 98.160  1.00 78.03  ? 402 SER   A O   1 
ATOM   2778 C  CB  . SER   A 1 402 ? 98.039  102.985 96.785  1.00 78.03  ? 402 SER   A CB  1 
ATOM   2779 O  OG  . SER   A 1 402 ? 98.020  101.622 96.400  1.00 78.03  ? 402 SER   A OG  1 
ATOM   2780 N  N   . GLN   A 1 403 ? 97.137  105.921 96.127  1.00 77.42  ? 403 GLN   A N   1 
ATOM   2781 C  CA  . GLN   A 1 403 ? 97.270  107.340 96.429  1.00 77.42  ? 403 GLN   A CA  1 
ATOM   2782 C  C   . GLN   A 1 403 ? 95.932  107.992 96.760  1.00 77.42  ? 403 GLN   A C   1 
ATOM   2783 O  O   . GLN   A 1 403 ? 95.847  108.724 97.737  1.00 77.42  ? 403 GLN   A O   1 
ATOM   2784 C  CB  . GLN   A 1 403 ? 97.941  108.090 95.273  1.00 77.42  ? 403 GLN   A CB  1 
ATOM   2785 C  CG  . GLN   A 1 403 ? 98.567  109.421 95.662  1.00 77.42  ? 403 GLN   A CG  1 
ATOM   2786 C  CD  . GLN   A 1 403 ? 99.920  109.263 96.333  1.00 77.42  ? 403 GLN   A CD  1 
ATOM   2787 O  OE1 . GLN   A 1 403 ? 100.316 110.087 97.159  1.00 77.42  ? 403 GLN   A OE1 1 
ATOM   2788 N  NE2 . GLN   A 1 403 ? 100.638 108.201 95.982  1.00 77.42  ? 403 GLN   A NE2 1 
ATOM   2789 N  N   . PHE   A 1 404 ? 94.876  107.712 95.998  1.00 84.08  ? 404 PHE   A N   1 
ATOM   2790 C  CA  . PHE   A 1 404 ? 93.628  108.409 96.301  1.00 84.08  ? 404 PHE   A CA  1 
ATOM   2791 C  C   . PHE   A 1 404 ? 92.920  107.808 97.503  1.00 84.08  ? 404 PHE   A C   1 
ATOM   2792 O  O   . PHE   A 1 404 ? 92.182  108.508 98.189  1.00 84.08  ? 404 PHE   A O   1 
ATOM   2793 C  CB  . PHE   A 1 404 ? 92.714  108.691 95.084  1.00 84.08  ? 404 PHE   A CB  1 
ATOM   2794 C  CG  . PHE   A 1 404 ? 92.261  107.477 94.318  1.00 84.08  ? 404 PHE   A CG  1 
ATOM   2795 C  CD1 . PHE   A 1 404 ? 92.556  107.362 92.971  1.00 84.08  ? 404 PHE   A CD1 1 
ATOM   2796 C  CD2 . PHE   A 1 404 ? 91.483  106.496 94.909  1.00 84.08  ? 404 PHE   A CD2 1 
ATOM   2797 C  CE1 . PHE   A 1 404 ? 92.128  106.272 92.240  1.00 84.08  ? 404 PHE   A CE1 1 
ATOM   2798 C  CE2 . PHE   A 1 404 ? 91.057  105.401 94.185  1.00 84.08  ? 404 PHE   A CE2 1 
ATOM   2799 C  CZ  . PHE   A 1 404 ? 91.373  105.291 92.847  1.00 84.08  ? 404 PHE   A CZ  1 
ATOM   2800 N  N   . VAL   A 1 405 ? 93.129  106.520 97.765  1.00 82.73  ? 405 VAL   A N   1 
ATOM   2801 C  CA  . VAL   A 1 405 ? 92.578  105.943 98.992  1.00 82.73  ? 405 VAL   A CA  1 
ATOM   2802 C  C   . VAL   A 1 405 ? 93.183  106.623 100.216 1.00 82.73  ? 405 VAL   A C   1 
ATOM   2803 O  O   . VAL   A 1 405 ? 92.468  107.025 101.145 1.00 82.73  ? 405 VAL   A O   1 
ATOM   2804 C  CB  . VAL   A 1 405 ? 92.791  104.419 99.026  1.00 82.73  ? 405 VAL   A CB  1 
ATOM   2805 C  CG1 . VAL   A 1 405 ? 92.403  103.868 100.385 1.00 82.73  ? 405 VAL   A CG1 1 
ATOM   2806 C  CG2 . VAL   A 1 405 ? 91.943  103.751 97.962  1.00 82.73  ? 405 VAL   A CG2 1 
ATOM   2807 N  N   . GLU   A 1 406 ? 94.511  106.779 100.228 1.00 80.86  ? 406 GLU   A N   1 
ATOM   2808 C  CA  . GLU   A 1 406 ? 95.153  107.451 101.356 1.00 80.86  ? 406 GLU   A CA  1 
ATOM   2809 C  C   . GLU   A 1 406 ? 94.727  108.912 101.449 1.00 80.86  ? 406 GLU   A C   1 
ATOM   2810 O  O   . GLU   A 1 406 ? 94.521  109.436 102.551 1.00 80.86  ? 406 GLU   A O   1 
ATOM   2811 C  CB  . GLU   A 1 406 ? 96.673  107.337 101.246 1.00 80.86  ? 406 GLU   A CB  1 
ATOM   2812 C  CG  . GLU   A 1 406 ? 97.185  105.909 101.145 1.00 80.86  ? 406 GLU   A CG  1 
ATOM   2813 C  CD  . GLU   A 1 406 ? 97.022  105.136 102.439 1.00 80.86  ? 406 GLU   A CD  1 
ATOM   2814 O  OE1 . GLU   A 1 406 ? 96.977  105.772 103.512 1.00 80.86  ? 406 GLU   A OE1 1 
ATOM   2815 O  OE2 . GLU   A 1 406 ? 96.938  103.892 102.382 1.00 80.86  ? 406 GLU   A OE2 1 
ATOM   2816 N  N   . VAL   A 1 407 ? 94.595  109.585 100.303 1.00 85.21  ? 407 VAL   A N   1 
ATOM   2817 C  CA  . VAL   A 1 407 ? 94.164  110.979 100.302 1.00 85.21  ? 407 VAL   A CA  1 
ATOM   2818 C  C   . VAL   A 1 407 ? 92.744  111.102 100.839 1.00 85.21  ? 407 VAL   A C   1 
ATOM   2819 O  O   . VAL   A 1 407 ? 92.443  112.004 101.628 1.00 85.21  ? 407 VAL   A O   1 
ATOM   2820 C  CB  . VAL   A 1 407 ? 94.297  111.577 98.890  1.00 85.21  ? 407 VAL   A CB  1 
ATOM   2821 C  CG1 . VAL   A 1 407 ? 93.530  112.883 98.791  1.00 85.21  ? 407 VAL   A CG1 1 
ATOM   2822 C  CG2 . VAL   A 1 407 ? 95.760  111.797 98.549  1.00 85.21  ? 407 VAL   A CG2 1 
ATOM   2823 N  N   . GLU   A 1 408 ? 91.850  110.200 100.428 1.00 90.25  ? 408 GLU   A N   1 
ATOM   2824 C  CA  . GLU   A 1 408 ? 90.488  110.214 100.947 1.00 90.25  ? 408 GLU   A CA  1 
ATOM   2825 C  C   . GLU   A 1 408 ? 90.483  110.007 102.454 1.00 90.25  ? 408 GLU   A C   1 
ATOM   2826 O  O   . GLU   A 1 408 ? 89.771  110.705 103.183 1.00 90.25  ? 408 GLU   A O   1 
ATOM   2827 C  CB  . GLU   A 1 408 ? 89.651  109.139 100.253 1.00 90.25  ? 408 GLU   A CB  1 
ATOM   2828 C  CG  . GLU   A 1 408 ? 88.777  109.656 99.122  1.00 90.25  ? 408 GLU   A CG  1 
ATOM   2829 C  CD  . GLU   A 1 408 ? 88.041  108.542 98.402  1.00 90.25  ? 408 GLU   A CD  1 
ATOM   2830 O  OE1 . GLU   A 1 408 ? 87.145  108.849 97.589  1.00 90.25  ? 408 GLU   A OE1 1 
ATOM   2831 O  OE2 . GLU   A 1 408 ? 88.358  107.360 98.652  1.00 90.25  ? 408 GLU   A OE2 1 
ATOM   2832 N  N   . GLY   A 1 409 ? 91.283  109.055 102.940 1.00 89.80  ? 409 GLY   A N   1 
ATOM   2833 C  CA  . GLY   A 1 409 ? 91.332  108.816 104.375 1.00 89.80  ? 409 GLY   A CA  1 
ATOM   2834 C  C   . GLY   A 1 409 ? 91.819  110.025 105.152 1.00 89.80  ? 409 GLY   A C   1 
ATOM   2835 O  O   . GLY   A 1 409 ? 91.215  110.426 106.153 1.00 89.80  ? 409 GLY   A O   1 
ATOM   2836 N  N   . GLN   A 1 410 ? 92.913  110.636 104.690 1.00 85.57  ? 410 GLN   A N   1 
ATOM   2837 C  CA  . GLN   A 1 410 ? 93.464  111.779 105.412 1.00 85.57  ? 410 GLN   A CA  1 
ATOM   2838 C  C   . GLN   A 1 410 ? 92.532  112.985 105.344 1.00 85.57  ? 410 GLN   A C   1 
ATOM   2839 O  O   . GLN   A 1 410 ? 92.366  113.701 106.339 1.00 85.57  ? 410 GLN   A O   1 
ATOM   2840 C  CB  . GLN   A 1 410 ? 94.859  112.123 104.882 1.00 85.57  ? 410 GLN   A CB  1 
ATOM   2841 C  CG  . GLN   A 1 410 ? 94.905  112.714 103.487 1.00 85.57  ? 410 GLN   A CG  1 
ATOM   2842 C  CD  . GLN   A 1 410 ? 96.317  112.822 102.954 1.00 85.57  ? 410 GLN   A CD  1 
ATOM   2843 O  OE1 . GLN   A 1 410 ? 96.887  113.910 102.888 1.00 85.57  ? 410 GLN   A OE1 1 
ATOM   2844 N  NE2 . GLN   A 1 410 ? 96.890  111.690 102.574 1.00 85.57  ? 410 GLN   A NE2 1 
ATOM   2845 N  N   . ILE   A 1 411 ? 91.896  113.218 104.194 1.00 94.85  ? 411 ILE   A N   1 
ATOM   2846 C  CA  . ILE   A 1 411 ? 90.978  114.345 104.079 1.00 94.85  ? 411 ILE   A CA  1 
ATOM   2847 C  C   . ILE   A 1 411 ? 89.743  114.114 104.938 1.00 94.85  ? 411 ILE   A C   1 
ATOM   2848 O  O   . ILE   A 1 411 ? 89.214  115.050 105.547 1.00 94.85  ? 411 ILE   A O   1 
ATOM   2849 C  CB  . ILE   A 1 411 ? 90.616  114.594 102.603 1.00 94.85  ? 411 ILE   A CB  1 
ATOM   2850 C  CG1 . ILE   A 1 411 ? 91.829  115.140 101.847 1.00 94.85  ? 411 ILE   A CG1 1 
ATOM   2851 C  CG2 . ILE   A 1 411 ? 89.450  115.563 102.486 1.00 94.85  ? 411 ILE   A CG2 1 
ATOM   2852 C  CD1 . ILE   A 1 411 ? 92.278  116.502 102.321 1.00 94.85  ? 411 ILE   A CD1 1 
ATOM   2853 N  N   . THR   A 1 412 ? 89.269  112.868 105.011 1.00 98.01  ? 412 THR   A N   1 
ATOM   2854 C  CA  . THR   A 1 412 ? 88.158  112.552 105.900 1.00 98.01  ? 412 THR   A CA  1 
ATOM   2855 C  C   . THR   A 1 412 ? 88.530  112.821 107.351 1.00 98.01  ? 412 THR   A C   1 
ATOM   2856 O  O   . THR   A 1 412 ? 87.735  113.388 108.109 1.00 98.01  ? 412 THR   A O   1 
ATOM   2857 C  CB  . THR   A 1 412 ? 87.737  111.094 105.720 1.00 98.01  ? 412 THR   A CB  1 
ATOM   2858 O  OG1 . THR   A 1 412 ? 87.586  110.807 104.324 1.00 98.01  ? 412 THR   A OG1 1 
ATOM   2859 C  CG2 . THR   A 1 412 ? 86.421  110.827 106.434 1.00 98.01  ? 412 THR   A CG2 1 
ATOM   2860 N  N   . SER   A 1 413 ? 89.740  112.428 107.753 1.00 99.73  ? 413 SER   A N   1 
ATOM   2861 C  CA  . SER   A 1 413 ? 90.181  112.707 109.117 1.00 99.73  ? 413 SER   A CA  1 
ATOM   2862 C  C   . SER   A 1 413 ? 90.239  114.208 109.384 1.00 99.73  ? 413 SER   A C   1 
ATOM   2863 O  O   . SER   A 1 413 ? 89.770  114.681 110.428 1.00 99.73  ? 413 SER   A O   1 
ATOM   2864 C  CB  . SER   A 1 413 ? 91.543  112.061 109.364 1.00 99.73  ? 413 SER   A CB  1 
ATOM   2865 O  OG  . SER   A 1 413 ? 91.552  110.714 108.924 1.00 99.73  ? 413 SER   A OG  1 
ATOM   2866 N  N   . LEU   A 1 414 ? 90.796  114.974 108.443 1.00 101.91 ? 414 LEU   A N   1 
ATOM   2867 C  CA  . LEU   A 1 414 ? 90.909  116.418 108.635 1.00 101.91 ? 414 LEU   A CA  1 
ATOM   2868 C  C   . LEU   A 1 414 ? 89.540  117.090 108.704 1.00 101.91 ? 414 LEU   A C   1 
ATOM   2869 O  O   . LEU   A 1 414 ? 89.327  117.987 109.527 1.00 101.91 ? 414 LEU   A O   1 
ATOM   2870 C  CB  . LEU   A 1 414 ? 91.759  117.039 107.526 1.00 101.91 ? 414 LEU   A CB  1 
ATOM   2871 C  CG  . LEU   A 1 414 ? 93.260  117.194 107.800 1.00 101.91 ? 414 LEU   A CG  1 
ATOM   2872 C  CD1 . LEU   A 1 414 ? 93.985  115.861 107.839 1.00 101.91 ? 414 LEU   A CD1 1 
ATOM   2873 C  CD2 . LEU   A 1 414 ? 93.892  118.110 106.765 1.00 101.91 ? 414 LEU   A CD2 1 
ATOM   2874 N  N   . VAL   A 1 415 ? 88.601  116.682 107.846 1.00 108.52 ? 415 VAL   A N   1 
ATOM   2875 C  CA  . VAL   A 1 415 ? 87.284  117.312 107.875 1.00 108.52 ? 415 VAL   A CA  1 
ATOM   2876 C  C   . VAL   A 1 415 ? 86.518  116.892 109.123 1.00 108.52 ? 415 VAL   A C   1 
ATOM   2877 O  O   . VAL   A 1 415 ? 85.726  117.675 109.662 1.00 108.52 ? 415 VAL   A O   1 
ATOM   2878 C  CB  . VAL   A 1 415 ? 86.486  117.009 106.590 1.00 108.52 ? 415 VAL   A CB  1 
ATOM   2879 C  CG1 . VAL   A 1 415 ? 87.206  117.566 105.367 1.00 108.52 ? 415 VAL   A CG1 1 
ATOM   2880 C  CG2 . VAL   A 1 415 ? 86.206  115.526 106.440 1.00 108.52 ? 415 VAL   A CG2 1 
ATOM   2881 N  N   . ASP   A 1 416 ? 86.732  115.665 109.607 1.00 110.39 ? 416 ASP   A N   1 
ATOM   2882 C  CA  . ASP   A 1 416 ? 86.112  115.241 110.855 1.00 110.39 ? 416 ASP   A CA  1 
ATOM   2883 C  C   . ASP   A 1 416 ? 86.724  115.948 112.057 1.00 110.39 ? 416 ASP   A C   1 
ATOM   2884 O  O   . ASP   A 1 416 ? 86.068  116.055 113.099 1.00 110.39 ? 416 ASP   A O   1 
ATOM   2885 C  CB  . ASP   A 1 416 ? 86.239  113.723 111.008 1.00 110.39 ? 416 ASP   A CB  1 
ATOM   2886 C  CG  . ASP   A 1 416 ? 85.613  113.207 112.291 1.00 110.39 ? 416 ASP   A CG  1 
ATOM   2887 O  OD1 . ASP   A 1 416 ? 84.599  113.783 112.738 1.00 110.39 ? 416 ASP   A OD1 1 
ATOM   2888 O  OD2 . ASP   A 1 416 ? 86.138  112.224 112.854 1.00 110.39 ? 416 ASP   A OD2 1 
ATOM   2889 N  N   . LEU   A 1 417 ? 87.960  116.439 111.932 1.00 109.27 ? 417 LEU   A N   1 
ATOM   2890 C  CA  . LEU   A 1 417 ? 88.571  117.188 113.026 1.00 109.27 ? 417 LEU   A CA  1 
ATOM   2891 C  C   . LEU   A 1 417 ? 87.763  118.436 113.364 1.00 109.27 ? 417 LEU   A C   1 
ATOM   2892 O  O   . LEU   A 1 417 ? 87.557  118.750 114.542 1.00 109.27 ? 417 LEU   A O   1 
ATOM   2893 C  CB  . LEU   A 1 417 ? 90.007  117.563 112.666 1.00 109.27 ? 417 LEU   A CB  1 
ATOM   2894 C  CG  . LEU   A 1 417 ? 91.076  116.517 112.978 1.00 109.27 ? 417 LEU   A CG  1 
ATOM   2895 C  CD1 . LEU   A 1 417 ? 92.462  117.068 112.691 1.00 109.27 ? 417 LEU   A CD1 1 
ATOM   2896 C  CD2 . LEU   A 1 417 ? 90.967  116.063 114.423 1.00 109.27 ? 417 LEU   A CD2 1 
ATOM   2897 N  N   . TYR   A 1 418 ? 87.299  119.159 112.348 1.00 120.04 ? 418 TYR   A N   1 
ATOM   2898 C  CA  . TYR   A 1 418 ? 86.485  120.358 112.539 1.00 120.04 ? 418 TYR   A CA  1 
ATOM   2899 C  C   . TYR   A 1 418 ? 85.301  120.308 111.581 1.00 120.04 ? 418 TYR   A C   1 
ATOM   2900 O  O   . TYR   A 1 418 ? 85.441  120.665 110.398 1.00 120.04 ? 418 TYR   A O   1 
ATOM   2901 C  CB  . TYR   A 1 418 ? 87.305  121.623 112.323 1.00 120.04 ? 418 TYR   A CB  1 
ATOM   2902 C  CG  . TYR   A 1 418 ? 86.830  122.805 113.137 1.00 120.04 ? 418 TYR   A CG  1 
ATOM   2903 C  CD1 . TYR   A 1 418 ? 87.272  122.999 114.438 1.00 120.04 ? 418 TYR   A CD1 1 
ATOM   2904 C  CD2 . TYR   A 1 418 ? 85.933  123.722 112.606 1.00 120.04 ? 418 TYR   A CD2 1 
ATOM   2905 C  CE1 . TYR   A 1 418 ? 86.839  124.077 115.187 1.00 120.04 ? 418 TYR   A CE1 1 
ATOM   2906 C  CE2 . TYR   A 1 418 ? 85.493  124.802 113.347 1.00 120.04 ? 418 TYR   A CE2 1 
ATOM   2907 C  CZ  . TYR   A 1 418 ? 85.950  124.974 114.636 1.00 120.04 ? 418 TYR   A CZ  1 
ATOM   2908 O  OH  . TYR   A 1 418 ? 85.514  126.049 115.377 1.00 120.04 ? 418 TYR   A OH  1 
ATOM   2909 N  N   . PRO   A 1 419 ? 84.127  119.874 112.044 1.00 123.65 ? 419 PRO   A N   1 
ATOM   2910 C  CA  . PRO   A 1 419 ? 82.974  119.764 111.142 1.00 123.65 ? 419 PRO   A CA  1 
ATOM   2911 C  C   . PRO   A 1 419 ? 82.142  121.035 111.069 1.00 123.65 ? 419 PRO   A C   1 
ATOM   2912 O  O   . PRO   A 1 419 ? 81.301  121.178 110.176 1.00 123.65 ? 419 PRO   A O   1 
ATOM   2913 C  CB  . PRO   A 1 419 ? 82.175  118.609 111.753 1.00 123.65 ? 419 PRO   A CB  1 
ATOM   2914 C  CG  . PRO   A 1 419 ? 82.466  118.705 113.224 1.00 123.65 ? 419 PRO   A CG  1 
ATOM   2915 C  CD  . PRO   A 1 419 ? 83.828  119.353 113.390 1.00 123.65 ? 419 PRO   A CD  1 
ATOM   2916 N  N   . SER   A 1 420 ? 82.360  121.961 112.005 1.00 125.80 ? 420 SER   A N   1 
ATOM   2917 C  CA  . SER   A 1 420 ? 81.573  123.191 112.024 1.00 125.80 ? 420 SER   A CA  1 
ATOM   2918 C  C   . SER   A 1 420 ? 81.899  124.081 110.830 1.00 125.80 ? 420 SER   A C   1 
ATOM   2919 O  O   . SER   A 1 420 ? 81.002  124.699 110.247 1.00 125.80 ? 420 SER   A O   1 
ATOM   2920 C  CB  . SER   A 1 420 ? 81.807  123.943 113.333 1.00 125.80 ? 420 SER   A CB  1 
ATOM   2921 O  OG  . SER   A 1 420 ? 81.283  123.225 114.436 1.00 125.80 ? 420 SER   A OG  1 
ATOM   2922 N  N   . PHE   A 1 421 ? 83.174  124.157 110.454 1.00 124.20 ? 421 PHE   A N   1 
ATOM   2923 C  CA  . PHE   A 1 421 ? 83.609  125.032 109.373 1.00 124.20 ? 421 PHE   A CA  1 
ATOM   2924 C  C   . PHE   A 1 421 ? 83.421  124.417 107.992 1.00 124.20 ? 421 PHE   A C   1 
ATOM   2925 O  O   . PHE   A 1 421 ? 83.635  125.109 106.990 1.00 124.20 ? 421 PHE   A O   1 
ATOM   2926 C  CB  . PHE   A 1 421 ? 85.081  125.408 109.576 1.00 124.20 ? 421 PHE   A CB  1 
ATOM   2927 C  CG  . PHE   A 1 421 ? 85.574  126.475 108.640 1.00 124.20 ? 421 PHE   A CG  1 
ATOM   2928 C  CD1 . PHE   A 1 421 ? 84.922  127.693 108.550 1.00 124.20 ? 421 PHE   A CD1 1 
ATOM   2929 C  CD2 . PHE   A 1 421 ? 86.687  126.255 107.846 1.00 124.20 ? 421 PHE   A CD2 1 
ATOM   2930 C  CE1 . PHE   A 1 421 ? 85.375  128.674 107.688 1.00 124.20 ? 421 PHE   A CE1 1 
ATOM   2931 C  CE2 . PHE   A 1 421 ? 87.144  127.231 106.983 1.00 124.20 ? 421 PHE   A CE2 1 
ATOM   2932 C  CZ  . PHE   A 1 421 ? 86.487  128.443 106.903 1.00 124.20 ? 421 PHE   A CZ  1 
ATOM   2933 N  N   . LEU   A 1 422 ? 83.015  123.154 107.906 1.00 123.99 ? 422 LEU   A N   1 
ATOM   2934 C  CA  . LEU   A 1 422 ? 82.978  122.446 106.637 1.00 123.99 ? 422 LEU   A CA  1 
ATOM   2935 C  C   . LEU   A 1 422 ? 81.629  121.775 106.429 1.00 123.99 ? 422 LEU   A C   1 
ATOM   2936 O  O   . LEU   A 1 422 ? 80.969  121.349 107.381 1.00 123.99 ? 422 LEU   A O   1 
ATOM   2937 C  CB  . LEU   A 1 422 ? 84.091  121.399 106.560 1.00 123.99 ? 422 LEU   A CB  1 
ATOM   2938 C  CG  . LEU   A 1 422 ? 85.490  121.976 106.362 1.00 123.99 ? 422 LEU   A CG  1 
ATOM   2939 C  CD1 . LEU   A 1 422 ? 86.538  120.905 106.597 1.00 123.99 ? 422 LEU   A CD1 1 
ATOM   2940 C  CD2 . LEU   A 1 422 ? 85.617  122.571 104.969 1.00 123.99 ? 422 LEU   A CD2 1 
ATOM   2941 N  N   . ARG   A 1 423 ? 81.232  121.686 105.162 1.00 127.06 ? 423 ARG   A N   1 
ATOM   2942 C  CA  . ARG   A 1 423 ? 80.010  121.008 104.762 1.00 127.06 ? 423 ARG   A CA  1 
ATOM   2943 C  C   . ARG   A 1 423 ? 80.222  120.433 103.370 1.00 127.06 ? 423 ARG   A C   1 
ATOM   2944 O  O   . ARG   A 1 423 ? 81.000  120.969 102.576 1.00 127.06 ? 423 ARG   A O   1 
ATOM   2945 C  CB  . ARG   A 1 423 ? 78.806  121.961 104.788 1.00 127.06 ? 423 ARG   A CB  1 
ATOM   2946 C  CG  . ARG   A 1 423 ? 77.463  121.296 104.524 1.00 127.06 ? 423 ARG   A CG  1 
ATOM   2947 C  CD  . ARG   A 1 423 ? 77.043  120.407 105.685 1.00 127.06 ? 423 ARG   A CD  1 
ATOM   2948 N  NE  . ARG   A 1 423 ? 76.403  121.163 106.755 1.00 127.06 ? 423 ARG   A NE  1 
ATOM   2949 C  CZ  . ARG   A 1 423 ? 76.076  120.656 107.936 1.00 127.06 ? 423 ARG   A CZ  1 
ATOM   2950 N  NH1 . ARG   A 1 423 ? 76.313  119.389 108.234 1.00 127.06 ? 423 ARG   A NH1 1 
ATOM   2951 N  NH2 . ARG   A 1 423 ? 75.494  121.439 108.839 1.00 127.06 ? 423 ARG   A NH2 1 
ATOM   2952 N  N   . LYS   A 1 424 ? 79.529  119.334 103.082 1.00 126.26 ? 424 LYS   A N   1 
ATOM   2953 C  CA  . LYS   A 1 424 ? 79.669  118.674 101.789 1.00 126.26 ? 424 LYS   A CA  1 
ATOM   2954 C  C   . LYS   A 1 424 ? 79.133  119.576 100.684 1.00 126.26 ? 424 LYS   A C   1 
ATOM   2955 O  O   . LYS   A 1 424 ? 77.930  119.856 100.628 1.00 126.26 ? 424 LYS   A O   1 
ATOM   2956 C  CB  . LYS   A 1 424 ? 78.934  117.336 101.796 1.00 126.26 ? 424 LYS   A CB  1 
ATOM   2957 C  CG  . LYS   A 1 424 ? 78.973  116.603 100.466 1.00 126.26 ? 424 LYS   A CG  1 
ATOM   2958 C  CD  . LYS   A 1 424 ? 80.403  116.338 100.027 1.00 126.26 ? 424 LYS   A CD  1 
ATOM   2959 C  CE  . LYS   A 1 424 ? 80.526  116.344 98.513  1.00 126.26 ? 424 LYS   A CE  1 
ATOM   2960 N  NZ  . LYS   A 1 424 ? 79.987  117.596 97.916  1.00 126.26 ? 424 LYS   A NZ  1 
ATOM   2961 N  N   . GLY   A 1 425 ? 80.020  120.026 99.809  1.00 127.92 ? 425 GLY   A N   1 
ATOM   2962 C  CA  . GLY   A 1 425 ? 79.636  120.921 98.729  1.00 127.92 ? 425 GLY   A CA  1 
ATOM   2963 C  C   . GLY   A 1 425 ? 80.861  121.601 98.136  1.00 127.92 ? 425 GLY   A C   1 
ATOM   2964 O  O   . GLY   A 1 425 ? 81.937  121.008 98.055  1.00 127.92 ? 425 GLY   A O   1 
ATOM   2965 N  N   . TYR   A 1 426 ? 80.663  122.857 97.726  1.00 125.59 ? 426 TYR   A N   1 
ATOM   2966 C  CA  . TYR   A 1 426 ? 81.740  123.618 97.101  1.00 125.59 ? 426 TYR   A CA  1 
ATOM   2967 C  C   . TYR   A 1 426 ? 82.881  123.915 98.066  1.00 125.59 ? 426 TYR   A C   1 
ATOM   2968 O  O   . TYR   A 1 426 ? 83.998  124.191 97.616  1.00 125.59 ? 426 TYR   A O   1 
ATOM   2969 C  CB  . TYR   A 1 426 ? 81.201  124.932 96.529  1.00 125.59 ? 426 TYR   A CB  1 
ATOM   2970 C  CG  . TYR   A 1 426 ? 79.931  124.801 95.714  1.00 125.59 ? 426 TYR   A CG  1 
ATOM   2971 C  CD1 . TYR   A 1 426 ? 79.690  123.678 94.931  1.00 125.59 ? 426 TYR   A CD1 1 
ATOM   2972 C  CD2 . TYR   A 1 426 ? 78.971  125.805 95.729  1.00 125.59 ? 426 TYR   A CD2 1 
ATOM   2973 C  CE1 . TYR   A 1 426 ? 78.530  123.561 94.188  1.00 125.59 ? 426 TYR   A CE1 1 
ATOM   2974 C  CE2 . TYR   A 1 426 ? 77.808  125.696 94.990  1.00 125.59 ? 426 TYR   A CE2 1 
ATOM   2975 C  CZ  . TYR   A 1 426 ? 77.593  124.573 94.221  1.00 125.59 ? 426 TYR   A CZ  1 
ATOM   2976 O  OH  . TYR   A 1 426 ? 76.436  124.462 93.484  1.00 125.59 ? 426 TYR   A OH  1 
ATOM   2977 N  N   . ARG   A 1 427 ? 82.629  123.866 99.376  1.00 121.06 ? 427 ARG   A N   1 
ATOM   2978 C  CA  . ARG   A 1 427 ? 83.644  124.235 100.356 1.00 121.06 ? 427 ARG   A CA  1 
ATOM   2979 C  C   . ARG   A 1 427 ? 84.805  123.249 100.417 1.00 121.06 ? 427 ARG   A C   1 
ATOM   2980 O  O   . ARG   A 1 427 ? 85.867  123.608 100.936 1.00 121.06 ? 427 ARG   A O   1 
ATOM   2981 C  CB  . ARG   A 1 427 ? 83.007  124.372 101.741 1.00 121.06 ? 427 ARG   A CB  1 
ATOM   2982 C  CG  . ARG   A 1 427 ? 83.780  125.275 102.690 1.00 121.06 ? 427 ARG   A CG  1 
ATOM   2983 C  CD  . ARG   A 1 427 ? 82.899  125.791 103.817 1.00 121.06 ? 427 ARG   A CD  1 
ATOM   2984 N  NE  . ARG   A 1 427 ? 82.320  127.093 103.509 1.00 121.06 ? 427 ARG   A NE  1 
ATOM   2985 C  CZ  . ARG   A 1 427 ? 81.646  127.837 104.375 1.00 121.06 ? 427 ARG   A CZ  1 
ATOM   2986 N  NH1 . ARG   A 1 427 ? 81.446  127.438 105.620 1.00 121.06 ? 427 ARG   A NH1 1 
ATOM   2987 N  NH2 . ARG   A 1 427 ? 81.161  129.012 103.982 1.00 121.06 ? 427 ARG   A NH2 1 
ATOM   2988 N  N   . ARG   A 1 428 ? 84.637  122.028 99.905  1.00 112.44 ? 428 ARG   A N   1 
ATOM   2989 C  CA  . ARG   A 1 428 ? 85.738  121.071 99.895  1.00 112.44 ? 428 ARG   A CA  1 
ATOM   2990 C  C   . ARG   A 1 428 ? 86.861  121.494 98.958  1.00 112.44 ? 428 ARG   A C   1 
ATOM   2991 O  O   . ARG   A 1 428 ? 87.998  121.033 99.124  1.00 112.44 ? 428 ARG   A O   1 
ATOM   2992 C  CB  . ARG   A 1 428 ? 85.229  119.685 99.497  1.00 112.44 ? 428 ARG   A CB  1 
ATOM   2993 C  CG  . ARG   A 1 428 ? 84.247  119.078 100.483 1.00 112.44 ? 428 ARG   A CG  1 
ATOM   2994 C  CD  . ARG   A 1 428 ? 84.925  118.067 101.391 1.00 112.44 ? 428 ARG   A CD  1 
ATOM   2995 N  NE  . ARG   A 1 428 ? 84.054  117.652 102.484 1.00 112.44 ? 428 ARG   A NE  1 
ATOM   2996 C  CZ  . ARG   A 1 428 ? 83.924  118.310 103.628 1.00 112.44 ? 428 ARG   A CZ  1 
ATOM   2997 N  NH1 . ARG   A 1 428 ? 84.597  119.424 103.865 1.00 112.44 ? 428 ARG   A NH1 1 
ATOM   2998 N  NH2 . ARG   A 1 428 ? 83.096  117.840 104.557 1.00 112.44 ? 428 ARG   A NH2 1 
ATOM   2999 N  N   . GLU   A 1 429 ? 86.566  122.357 97.982  1.00 106.96 ? 429 GLU   A N   1 
ATOM   3000 C  CA  . GLU   A 1 429 ? 87.583  122.787 97.032  1.00 106.96 ? 429 GLU   A CA  1 
ATOM   3001 C  C   . GLU   A 1 429 ? 88.738  123.489 97.727  1.00 106.96 ? 429 GLU   A C   1 
ATOM   3002 O  O   . GLU   A 1 429 ? 89.899  123.276 97.364  1.00 106.96 ? 429 GLU   A O   1 
ATOM   3003 C  CB  . GLU   A 1 429 ? 86.965  123.709 95.980  1.00 106.96 ? 429 GLU   A CB  1 
ATOM   3004 C  CG  . GLU   A 1 429 ? 85.981  123.023 95.048  1.00 106.96 ? 429 GLU   A CG  1 
ATOM   3005 C  CD  . GLU   A 1 429 ? 86.650  122.021 94.130  1.00 106.96 ? 429 GLU   A CD  1 
ATOM   3006 O  OE1 . GLU   A 1 429 ? 87.814  122.251 93.743  1.00 106.96 ? 429 GLU   A OE1 1 
ATOM   3007 O  OE2 . GLU   A 1 429 ? 86.011  121.001 93.798  1.00 106.96 ? 429 GLU   A OE2 1 
ATOM   3008 N  N   . ILE   A 1 430 ? 88.443  124.323 98.725  1.00 100.87 ? 430 ILE   A N   1 
ATOM   3009 C  CA  . ILE   A 1 430 ? 89.493  125.082 99.401  1.00 100.87 ? 430 ILE   A CA  1 
ATOM   3010 C  C   . ILE   A 1 430 ? 90.489  124.136 100.062 1.00 100.87 ? 430 ILE   A C   1 
ATOM   3011 O  O   . ILE   A 1 430 ? 91.700  124.215 99.823  1.00 100.87 ? 430 ILE   A O   1 
ATOM   3012 C  CB  . ILE   A 1 430 ? 88.881  126.054 100.425 1.00 100.87 ? 430 ILE   A CB  1 
ATOM   3013 C  CG1 . ILE   A 1 430 ? 88.042  127.126 99.723  1.00 100.87 ? 430 ILE   A CG1 1 
ATOM   3014 C  CG2 . ILE   A 1 430 ? 89.970  126.691 101.275 1.00 100.87 ? 430 ILE   A CG2 1 
ATOM   3015 C  CD1 . ILE   A 1 430 ? 86.563  126.803 99.646  1.00 100.87 ? 430 ILE   A CD1 1 
ATOM   3016 N  N   . PHE   A 1 431 ? 89.988  123.204 100.876 1.00 101.53 ? 431 PHE   A N   1 
ATOM   3017 C  CA  . PHE   A 1 431 ? 90.877  122.317 101.618 1.00 101.53 ? 431 PHE   A CA  1 
ATOM   3018 C  C   . PHE   A 1 431 ? 91.393  121.147 100.795 1.00 101.53 ? 431 PHE   A C   1 
ATOM   3019 O  O   . PHE   A 1 431 ? 92.242  120.402 101.294 1.00 101.53 ? 431 PHE   A O   1 
ATOM   3020 C  CB  . PHE   A 1 431 ? 90.196  121.789 102.882 1.00 101.53 ? 431 PHE   A CB  1 
ATOM   3021 C  CG  . PHE   A 1 431 ? 89.961  122.839 103.928 1.00 101.53 ? 431 PHE   A CG  1 
ATOM   3022 C  CD1 . PHE   A 1 431 ? 90.601  124.065 103.854 1.00 101.53 ? 431 PHE   A CD1 1 
ATOM   3023 C  CD2 . PHE   A 1 431 ? 89.126  122.590 105.001 1.00 101.53 ? 431 PHE   A CD2 1 
ATOM   3024 C  CE1 . PHE   A 1 431 ? 90.394  125.031 104.820 1.00 101.53 ? 431 PHE   A CE1 1 
ATOM   3025 C  CE2 . PHE   A 1 431 ? 88.914  123.551 105.971 1.00 101.53 ? 431 PHE   A CE2 1 
ATOM   3026 C  CZ  . PHE   A 1 431 ? 89.550  124.773 105.881 1.00 101.53 ? 431 PHE   A CZ  1 
ATOM   3027 N  N   . ILE   A 1 432 ? 90.914  120.950 99.572  1.00 87.47  ? 432 ILE   A N   1 
ATOM   3028 C  CA  . ILE   A 1 432 ? 91.587  120.007 98.684  1.00 87.47  ? 432 ILE   A CA  1 
ATOM   3029 C  C   . ILE   A 1 432 ? 92.699  120.691 97.899  1.00 87.47  ? 432 ILE   A C   1 
ATOM   3030 O  O   . ILE   A 1 432 ? 93.818  120.178 97.815  1.00 87.47  ? 432 ILE   A O   1 
ATOM   3031 C  CB  . ILE   A 1 432 ? 90.573  119.317 97.750  1.00 87.47  ? 432 ILE   A CB  1 
ATOM   3032 C  CG1 . ILE   A 1 432 ? 89.603  118.466 98.566  1.00 87.47  ? 432 ILE   A CG1 1 
ATOM   3033 C  CG2 . ILE   A 1 432 ? 91.295  118.426 96.762  1.00 87.47  ? 432 ILE   A CG2 1 
ATOM   3034 C  CD1 . ILE   A 1 432 ? 90.278  117.371 99.353  1.00 87.47  ? 432 ILE   A CD1 1 
ATOM   3035 N  N   . ALA   A 1 433 ? 92.416  121.866 97.328  1.00 81.45  ? 433 ALA   A N   1 
ATOM   3036 C  CA  . ALA   A 1 433 ? 93.434  122.596 96.582  1.00 81.45  ? 433 ALA   A CA  1 
ATOM   3037 C  C   . ALA   A 1 433 ? 94.588  123.017 97.482  1.00 81.45  ? 433 ALA   A C   1 
ATOM   3038 O  O   . ALA   A 1 433 ? 95.753  122.953 97.075  1.00 81.45  ? 433 ALA   A O   1 
ATOM   3039 C  CB  . ALA   A 1 433 ? 92.813  123.816 95.903  1.00 81.45  ? 433 ALA   A CB  1 
ATOM   3040 N  N   . PHE   A 1 434 ? 94.286  123.450 98.709  1.00 77.27  ? 434 PHE   A N   1 
ATOM   3041 C  CA  . PHE   A 1 434 ? 95.335  123.876 99.629  1.00 77.27  ? 434 PHE   A CA  1 
ATOM   3042 C  C   . PHE   A 1 434 ? 96.297  122.732 99.928  1.00 77.27  ? 434 PHE   A C   1 
ATOM   3043 O  O   . PHE   A 1 434 ? 97.520  122.889 99.827  1.00 77.27  ? 434 PHE   A O   1 
ATOM   3044 C  CB  . PHE   A 1 434 ? 94.690  124.404 100.912 1.00 77.27  ? 434 PHE   A CB  1 
ATOM   3045 C  CG  . PHE   A 1 434 ? 95.583  125.287 101.734 1.00 77.27  ? 434 PHE   A CG  1 
ATOM   3046 C  CD1 . PHE   A 1 434 ? 95.985  126.522 101.258 1.00 77.27  ? 434 PHE   A CD1 1 
ATOM   3047 C  CD2 . PHE   A 1 434 ? 95.987  124.898 102.999 1.00 77.27  ? 434 PHE   A CD2 1 
ATOM   3048 C  CE1 . PHE   A 1 434 ? 96.796  127.341 102.017 1.00 77.27  ? 434 PHE   A CE1 1 
ATOM   3049 C  CE2 . PHE   A 1 434 ? 96.794  125.714 103.764 1.00 77.27  ? 434 PHE   A CE2 1 
ATOM   3050 C  CZ  . PHE   A 1 434 ? 97.202  126.936 103.272 1.00 77.27  ? 434 PHE   A CZ  1 
ATOM   3051 N  N   . VAL   A 1 435 ? 95.755  121.562 100.273 1.00 70.83  ? 435 VAL   A N   1 
ATOM   3052 C  CA  . VAL   A 1 435 ? 96.597  120.418 100.605 1.00 70.83  ? 435 VAL   A CA  1 
ATOM   3053 C  C   . VAL   A 1 435 ? 97.360  119.938 99.378  1.00 70.83  ? 435 VAL   A C   1 
ATOM   3054 O  O   . VAL   A 1 435 ? 98.547  119.597 99.466  1.00 70.83  ? 435 VAL   A O   1 
ATOM   3055 C  CB  . VAL   A 1 435 ? 95.751  119.294 101.225 1.00 70.83  ? 435 VAL   A CB  1 
ATOM   3056 C  CG1 . VAL   A 1 435 ? 96.599  118.056 101.450 1.00 70.83  ? 435 VAL   A CG1 1 
ATOM   3057 C  CG2 . VAL   A 1 435 ? 95.136  119.761 102.533 1.00 70.83  ? 435 VAL   A CG2 1 
ATOM   3058 N  N   . CYS   A 1 436 ? 96.700  119.902 98.217  1.00 73.46  ? 436 CYS   A N   1 
ATOM   3059 C  CA  . CYS   A 1 436 ? 97.378  119.468 96.999  1.00 73.46  ? 436 CYS   A CA  1 
ATOM   3060 C  C   . CYS   A 1 436 ? 98.545  120.388 96.663  1.00 73.46  ? 436 CYS   A C   1 
ATOM   3061 O  O   . CYS   A 1 436 ? 99.639  119.923 96.325  1.00 73.46  ? 436 CYS   A O   1 
ATOM   3062 C  CB  . CYS   A 1 436 ? 96.384  119.409 95.838  1.00 73.46  ? 436 CYS   A CB  1 
ATOM   3063 S  SG  . CYS   A 1 436 ? 95.155  118.088 95.957  1.00 73.46  ? 436 CYS   A SG  1 
ATOM   3064 N  N   . SER   A 1 437 ? 98.334  121.703 96.761  1.00 70.80  ? 437 SER   A N   1 
ATOM   3065 C  CA  . SER   A 1 437 ? 99.400  122.649 96.452  1.00 70.80  ? 437 SER   A CA  1 
ATOM   3066 C  C   . SER   A 1 437 ? 100.536 122.559 97.462  1.00 70.80  ? 437 SER   A C   1 
ATOM   3067 O  O   . SER   A 1 437 ? 101.713 122.617 97.083  1.00 70.80  ? 437 SER   A O   1 
ATOM   3068 C  CB  . SER   A 1 437 ? 98.839  124.068 96.398  1.00 70.80  ? 437 SER   A CB  1 
ATOM   3069 O  OG  . SER   A 1 437 ? 97.905  124.201 95.341  1.00 70.80  ? 437 SER   A OG  1 
ATOM   3070 N  N   . ILE   A 1 438 ? 100.212 122.417 98.750  1.00 67.20  ? 438 ILE   A N   1 
ATOM   3071 C  CA  . ILE   A 1 438 ? 101.260 122.304 99.762  1.00 67.20  ? 438 ILE   A CA  1 
ATOM   3072 C  C   . ILE   A 1 438 ? 102.099 121.058 99.517  1.00 67.20  ? 438 ILE   A C   1 
ATOM   3073 O  O   . ILE   A 1 438 ? 103.333 121.100 99.573  1.00 67.20  ? 438 ILE   A O   1 
ATOM   3074 C  CB  . ILE   A 1 438 ? 100.654 122.304 101.176 1.00 67.20  ? 438 ILE   A CB  1 
ATOM   3075 C  CG1 . ILE   A 1 438 ? 100.125 123.690 101.534 1.00 67.20  ? 438 ILE   A CG1 1 
ATOM   3076 C  CG2 . ILE   A 1 438 ? 101.684 121.853 102.199 1.00 67.20  ? 438 ILE   A CG2 1 
ATOM   3077 C  CD1 . ILE   A 1 438 ? 99.433  123.732 102.869 1.00 67.20  ? 438 ILE   A CD1 1 
ATOM   3078 N  N   . SER   A 1 439 ? 101.442 119.929 99.241  1.00 59.78  ? 439 SER   A N   1 
ATOM   3079 C  CA  . SER   A 1 439 ? 102.179 118.697 98.988  1.00 59.78  ? 439 SER   A CA  1 
ATOM   3080 C  C   . SER   A 1 439 ? 103.014 118.802 97.720  1.00 59.78  ? 439 SER   A C   1 
ATOM   3081 O  O   . SER   A 1 439 ? 104.159 118.337 97.687  1.00 59.78  ? 439 SER   A O   1 
ATOM   3082 C  CB  . SER   A 1 439 ? 101.213 117.519 98.906  1.00 59.78  ? 439 SER   A CB  1 
ATOM   3083 O  OG  . SER   A 1 439 ? 100.379 117.468 100.050 1.00 59.78  ? 439 SER   A OG  1 
ATOM   3084 N  N   . TYR   A 1 440 ? 102.464 119.420 96.671  1.00 65.90  ? 440 TYR   A N   1 
ATOM   3085 C  CA  . TYR   A 1 440 ? 103.215 119.594 95.432  1.00 65.90  ? 440 TYR   A CA  1 
ATOM   3086 C  C   . TYR   A 1 440 ? 104.460 120.443 95.653  1.00 65.90  ? 440 TYR   A C   1 
ATOM   3087 O  O   . TYR   A 1 440 ? 105.540 120.119 95.144  1.00 65.90  ? 440 TYR   A O   1 
ATOM   3088 C  CB  . TYR   A 1 440 ? 102.322 120.232 94.367  1.00 65.90  ? 440 TYR   A CB  1 
ATOM   3089 C  CG  . TYR   A 1 440 ? 103.044 120.551 93.078  1.00 65.90  ? 440 TYR   A CG  1 
ATOM   3090 C  CD1 . TYR   A 1 440 ? 103.578 119.543 92.296  1.00 65.90  ? 440 TYR   A CD1 1 
ATOM   3091 C  CD2 . TYR   A 1 440 ? 103.196 121.861 92.648  1.00 65.90  ? 440 TYR   A CD2 1 
ATOM   3092 C  CE1 . TYR   A 1 440 ? 104.242 119.821 91.122  1.00 65.90  ? 440 TYR   A CE1 1 
ATOM   3093 C  CE2 . TYR   A 1 440 ? 103.859 122.153 91.471  1.00 65.90  ? 440 TYR   A CE2 1 
ATOM   3094 C  CZ  . TYR   A 1 440 ? 104.380 121.126 90.713  1.00 65.90  ? 440 TYR   A CZ  1 
ATOM   3095 O  OH  . TYR   A 1 440 ? 105.043 121.399 89.540  1.00 65.90  ? 440 TYR   A OH  1 
ATOM   3096 N  N   . LEU   A 1 441 ? 104.329 121.533 96.409  1.00 63.46  ? 441 LEU   A N   1 
ATOM   3097 C  CA  . LEU   A 1 441 ? 105.470 122.408 96.653  1.00 63.46  ? 441 LEU   A CA  1 
ATOM   3098 C  C   . LEU   A 1 441 ? 106.504 121.726 97.542  1.00 63.46  ? 441 LEU   A C   1 
ATOM   3099 O  O   . LEU   A 1 441 ? 107.713 121.841 97.311  1.00 63.46  ? 441 LEU   A O   1 
ATOM   3100 C  CB  . LEU   A 1 441 ? 104.994 123.721 97.274  1.00 63.46  ? 441 LEU   A CB  1 
ATOM   3101 C  CG  . LEU   A 1 441 ? 104.432 124.746 96.285  1.00 63.46  ? 441 LEU   A CG  1 
ATOM   3102 C  CD1 . LEU   A 1 441 ? 104.200 126.085 96.969  1.00 63.46  ? 441 LEU   A CD1 1 
ATOM   3103 C  CD2 . LEU   A 1 441 ? 105.353 124.903 95.084  1.00 63.46  ? 441 LEU   A CD2 1 
ATOM   3104 N  N   . LEU   A 1 442 ? 106.045 121.007 98.569  1.00 58.91  ? 442 LEU   A N   1 
ATOM   3105 C  CA  . LEU   A 1 442 ? 106.971 120.373 99.501  1.00 58.91  ? 442 LEU   A CA  1 
ATOM   3106 C  C   . LEU   A 1 442 ? 107.711 119.211 98.850  1.00 58.91  ? 442 LEU   A C   1 
ATOM   3107 O  O   . LEU   A 1 442 ? 108.894 118.994 99.134  1.00 58.91  ? 442 LEU   A O   1 
ATOM   3108 C  CB  . LEU   A 1 442 ? 106.208 119.918 100.749 1.00 58.91  ? 442 LEU   A CB  1 
ATOM   3109 C  CG  . LEU   A 1 442 ? 106.901 119.668 102.095 1.00 58.91  ? 442 LEU   A CG  1 
ATOM   3110 C  CD1 . LEU   A 1 442 ? 105.846 119.402 103.155 1.00 58.91  ? 442 LEU   A CD1 1 
ATOM   3111 C  CD2 . LEU   A 1 442 ? 107.889 118.514 102.059 1.00 58.91  ? 442 LEU   A CD2 1 
ATOM   3112 N  N   . GLY   A 1 443 ? 107.050 118.470 97.959  1.00 58.24  ? 443 GLY   A N   1 
ATOM   3113 C  CA  . GLY   A 1 443 ? 107.688 117.363 97.283  1.00 58.24  ? 443 GLY   A CA  1 
ATOM   3114 C  C   . GLY   A 1 443 ? 108.550 117.748 96.108  1.00 58.24  ? 443 GLY   A C   1 
ATOM   3115 O  O   . GLY   A 1 443 ? 109.013 116.872 95.373  1.00 58.24  ? 443 GLY   A O   1 
ATOM   3116 N  N   . LEU   A 1 444 ? 108.779 119.042 95.906  1.00 59.08  ? 444 LEU   A N   1 
ATOM   3117 C  CA  . LEU   A 1 444 ? 109.629 119.543 94.837  1.00 59.08  ? 444 LEU   A CA  1 
ATOM   3118 C  C   . LEU   A 1 444 ? 111.112 119.438 95.168  1.00 59.08  ? 444 LEU   A C   1 
ATOM   3119 O  O   . LEU   A 1 444 ? 111.948 119.694 94.296  1.00 59.08  ? 444 LEU   A O   1 
ATOM   3120 C  CB  . LEU   A 1 444 ? 109.265 120.999 94.529  1.00 59.08  ? 444 LEU   A CB  1 
ATOM   3121 C  CG  . LEU   A 1 444 ? 109.590 121.550 93.141  1.00 59.08  ? 444 LEU   A CG  1 
ATOM   3122 C  CD1 . LEU   A 1 444 ? 109.007 120.653 92.063  1.00 59.08  ? 444 LEU   A CD1 1 
ATOM   3123 C  CD2 . LEU   A 1 444 ? 109.064 122.969 92.999  1.00 59.08  ? 444 LEU   A CD2 1 
ATOM   3124 N  N   . THR   A 1 445 ? 111.455 119.063 96.398  1.00 50.80  ? 445 THR   A N   1 
ATOM   3125 C  CA  . THR   A 1 445 ? 112.839 118.955 96.837  1.00 50.80  ? 445 THR   A CA  1 
ATOM   3126 C  C   . THR   A 1 445 ? 113.437 117.574 96.604  1.00 50.80  ? 445 THR   A C   1 
ATOM   3127 O  O   . THR   A 1 445 ? 114.598 117.351 96.960  1.00 50.80  ? 445 THR   A O   1 
ATOM   3128 C  CB  . THR   A 1 445 ? 112.947 119.311 98.323  1.00 50.80  ? 445 THR   A CB  1 
ATOM   3129 O  OG1 . THR   A 1 445 ? 112.147 118.404 99.089  1.00 50.80  ? 445 THR   A OG1 1 
ATOM   3130 C  CG2 . THR   A 1 445 ? 112.461 120.729 98.565  1.00 50.80  ? 445 THR   A CG2 1 
ATOM   3131 N  N   . MET   A 1 446 ? 112.677 116.645 96.025  1.00 51.16  ? 446 MET   A N   1 
ATOM   3132 C  CA  . MET   A 1 446 ? 113.172 115.312 95.719  1.00 51.16  ? 446 MET   A CA  1 
ATOM   3133 C  C   . MET   A 1 446 ? 113.270 115.039 94.227  1.00 51.16  ? 446 MET   A C   1 
ATOM   3134 O  O   . MET   A 1 446 ? 113.801 113.992 93.838  1.00 51.16  ? 446 MET   A O   1 
ATOM   3135 C  CB  . MET   A 1 446 ? 112.286 114.249 96.379  1.00 51.16  ? 446 MET   A CB  1 
ATOM   3136 C  CG  . MET   A 1 446 ? 112.351 114.262 97.889  1.00 51.16  ? 446 MET   A CG  1 
ATOM   3137 S  SD  . MET   A 1 446 ? 111.355 112.972 98.643  1.00 51.16  ? 446 MET   A SD  1 
ATOM   3138 C  CE  . MET   A 1 446 ? 109.724 113.650 98.385  1.00 51.16  ? 446 MET   A CE  1 
ATOM   3139 N  N   . VAL   A 1 447 ? 112.770 115.942 93.382  1.00 59.19  ? 447 VAL   A N   1 
ATOM   3140 C  CA  . VAL   A 1 447 ? 112.906 115.799 91.936  1.00 59.19  ? 447 VAL   A CA  1 
ATOM   3141 C  C   . VAL   A 1 447 ? 114.094 116.576 91.390  1.00 59.19  ? 447 VAL   A C   1 
ATOM   3142 O  O   . VAL   A 1 447 ? 114.461 116.382 90.220  1.00 59.19  ? 447 VAL   A O   1 
ATOM   3143 C  CB  . VAL   A 1 447 ? 111.616 116.235 91.209  1.00 59.19  ? 447 VAL   A CB  1 
ATOM   3144 C  CG1 . VAL   A 1 447 ? 110.477 115.288 91.544  1.00 59.19  ? 447 VAL   A CG1 1 
ATOM   3145 C  CG2 . VAL   A 1 447 ? 111.253 117.660 91.583  1.00 59.19  ? 447 VAL   A CG2 1 
ATOM   3146 N  N   . THR   A 1 448 ? 114.704 117.445 92.191  1.00 60.82  ? 448 THR   A N   1 
ATOM   3147 C  CA  . THR   A 1 448 ? 115.927 118.126 91.807  1.00 60.82  ? 448 THR   A CA  1 
ATOM   3148 C  C   . THR   A 1 448 ? 117.087 117.140 91.771  1.00 60.82  ? 448 THR   A C   1 
ATOM   3149 O  O   . THR   A 1 448 ? 117.043 116.068 92.379  1.00 60.82  ? 448 THR   A O   1 
ATOM   3150 C  CB  . THR   A 1 448 ? 116.250 119.248 92.791  1.00 60.82  ? 448 THR   A CB  1 
ATOM   3151 O  OG1 . THR   A 1 448 ? 116.704 118.676 94.023  1.00 60.82  ? 448 THR   A OG1 1 
ATOM   3152 C  CG2 . THR   A 1 448 ? 115.015 120.072 93.073  1.00 60.82  ? 448 THR   A CG2 1 
ATOM   3153 N  N   . GLU   A 1 449 ? 118.137 117.510 91.042  1.00 65.39  ? 449 GLU   A N   1 
ATOM   3154 C  CA  . GLU   A 1 449 ? 119.356 116.716 91.068  1.00 65.39  ? 449 GLU   A CA  1 
ATOM   3155 C  C   . GLU   A 1 449 ? 119.942 116.722 92.474  1.00 65.39  ? 449 GLU   A C   1 
ATOM   3156 O  O   . GLU   A 1 449 ? 120.098 117.778 93.093  1.00 65.39  ? 449 GLU   A O   1 
ATOM   3157 C  CB  . GLU   A 1 449 ? 120.364 117.249 90.046  1.00 65.39  ? 449 GLU   A CB  1 
ATOM   3158 C  CG  . GLU   A 1 449 ? 120.764 118.698 90.237  1.00 65.39  ? 449 GLU   A CG  1 
ATOM   3159 C  CD  . GLU   A 1 449 ? 121.690 119.196 89.148  1.00 65.39  ? 449 GLU   A CD  1 
ATOM   3160 O  OE1 . GLU   A 1 449 ? 122.013 118.409 88.234  1.00 65.39  ? 449 GLU   A OE1 1 
ATOM   3161 O  OE2 . GLU   A 1 449 ? 122.094 120.376 89.205  1.00 65.39  ? 449 GLU   A OE2 1 
ATOM   3162 N  N   . GLY   A 1 450 ? 120.246 115.531 92.984  1.00 61.63  ? 450 GLY   A N   1 
ATOM   3163 C  CA  . GLY   A 1 450 ? 120.573 115.361 94.381  1.00 61.63  ? 450 GLY   A CA  1 
ATOM   3164 C  C   . GLY   A 1 450 ? 119.377 115.181 95.289  1.00 61.63  ? 450 GLY   A C   1 
ATOM   3165 O  O   . GLY   A 1 450 ? 119.550 115.144 96.513  1.00 61.63  ? 450 GLY   A O   1 
ATOM   3166 N  N   . GLY   A 1 451 ? 118.168 115.086 94.731  1.00 57.95  ? 451 GLY   A N   1 
ATOM   3167 C  CA  . GLY   A 1 451 ? 116.994 114.866 95.560  1.00 57.95  ? 451 GLY   A CA  1 
ATOM   3168 C  C   . GLY   A 1 451 ? 116.782 113.404 95.903  1.00 57.95  ? 451 GLY   A C   1 
ATOM   3169 O  O   . GLY   A 1 451 ? 115.890 113.064 96.685  1.00 57.95  ? 451 GLY   A O   1 
ATOM   3170 N  N   . MET   A 1 452 ? 117.584 112.519 95.313  1.00 59.07  ? 452 MET   A N   1 
ATOM   3171 C  CA  . MET   A 1 452 ? 117.513 111.095 95.610  1.00 59.07  ? 452 MET   A CA  1 
ATOM   3172 C  C   . MET   A 1 452 ? 117.841 110.837 97.076  1.00 59.07  ? 452 MET   A C   1 
ATOM   3173 O  O   . MET   A 1 452 ? 117.209 109.996 97.722  1.00 59.07  ? 452 MET   A O   1 
ATOM   3174 C  CB  . MET   A 1 452 ? 118.467 110.317 94.701  1.00 59.07  ? 452 MET   A CB  1 
ATOM   3175 C  CG  . MET   A 1 452 ? 118.623 108.842 95.045  1.00 59.07  ? 452 MET   A CG  1 
ATOM   3176 S  SD  . MET   A 1 452 ? 117.063 107.983 95.331  1.00 59.07  ? 452 MET   A SD  1 
ATOM   3177 C  CE  . MET   A 1 452 ? 116.961 106.973 93.856  1.00 59.07  ? 452 MET   A CE  1 
ATOM   3178 N  N   . TYR   A 1 453 ? 118.834 111.555 97.604  1.00 55.52  ? 453 TYR   A N   1 
ATOM   3179 C  CA  . TYR   A 1 453 ? 119.268 111.336 98.980  1.00 55.52  ? 453 TYR   A CA  1 
ATOM   3180 C  C   . TYR   A 1 453 ? 118.171 111.702 99.973  1.00 55.52  ? 453 TYR   A C   1 
ATOM   3181 O  O   . TYR   A 1 453 ? 117.954 110.996 100.966 1.00 55.52  ? 453 TYR   A O   1 
ATOM   3182 C  CB  . TYR   A 1 453 ? 120.537 112.137 99.255  1.00 55.52  ? 453 TYR   A CB  1 
ATOM   3183 C  CG  . TYR   A 1 453 ? 121.714 111.704 98.415  1.00 55.52  ? 453 TYR   A CG  1 
ATOM   3184 C  CD1 . TYR   A 1 453 ? 122.327 110.479 98.625  1.00 55.52  ? 453 TYR   A CD1 1 
ATOM   3185 C  CD2 . TYR   A 1 453 ? 122.211 112.520 97.411  1.00 55.52  ? 453 TYR   A CD2 1 
ATOM   3186 C  CE1 . TYR   A 1 453 ? 123.402 110.079 97.860  1.00 55.52  ? 453 TYR   A CE1 1 
ATOM   3187 C  CE2 . TYR   A 1 453 ? 123.284 112.130 96.640  1.00 55.52  ? 453 TYR   A CE2 1 
ATOM   3188 C  CZ  . TYR   A 1 453 ? 123.876 110.908 96.869  1.00 55.52  ? 453 TYR   A CZ  1 
ATOM   3189 O  OH  . TYR   A 1 453 ? 124.948 110.513 96.102  1.00 55.52  ? 453 TYR   A OH  1 
ATOM   3190 N  N   . VAL   A 1 454 ? 117.471 112.812 99.727  1.00 49.64  ? 454 VAL   A N   1 
ATOM   3191 C  CA  . VAL   A 1 454 ? 116.359 113.186 100.596 1.00 49.64  ? 454 VAL   A CA  1 
ATOM   3192 C  C   . VAL   A 1 454 ? 115.258 112.139 100.521 1.00 49.64  ? 454 VAL   A C   1 
ATOM   3193 O  O   . VAL   A 1 454 ? 114.622 111.816 101.533 1.00 49.64  ? 454 VAL   A O   1 
ATOM   3194 C  CB  . VAL   A 1 454 ? 115.841 114.589 100.226 1.00 49.64  ? 454 VAL   A CB  1 
ATOM   3195 C  CG1 . VAL   A 1 454 ? 114.439 114.806 100.765 1.00 49.64  ? 454 VAL   A CG1 1 
ATOM   3196 C  CG2 . VAL   A 1 454 ? 116.786 115.659 100.744 1.00 49.64  ? 454 VAL   A CG2 1 
ATOM   3197 N  N   . PHE   A 1 455 ? 115.026 111.581 99.331  1.00 54.43  ? 455 PHE   A N   1 
ATOM   3198 C  CA  . PHE   A 1 455 ? 114.036 110.520 99.181  1.00 54.43  ? 455 PHE   A CA  1 
ATOM   3199 C  C   . PHE   A 1 455 ? 114.421 109.285 99.986  1.00 54.43  ? 455 PHE   A C   1 
ATOM   3200 O  O   . PHE   A 1 455 ? 113.571 108.660 100.628 1.00 54.43  ? 455 PHE   A O   1 
ATOM   3201 C  CB  . PHE   A 1 455 ? 113.870 110.163 97.705  1.00 54.43  ? 455 PHE   A CB  1 
ATOM   3202 C  CG  . PHE   A 1 455 ? 112.996 108.969 97.472  1.00 54.43  ? 455 PHE   A CG  1 
ATOM   3203 C  CD1 . PHE   A 1 455 ? 111.668 108.980 97.861  1.00 54.43  ? 455 PHE   A CD1 1 
ATOM   3204 C  CD2 . PHE   A 1 455 ? 113.506 107.829 96.878  1.00 54.43  ? 455 PHE   A CD2 1 
ATOM   3205 C  CE1 . PHE   A 1 455 ? 110.863 107.880 97.653  1.00 54.43  ? 455 PHE   A CE1 1 
ATOM   3206 C  CE2 . PHE   A 1 455 ? 112.707 106.728 96.668  1.00 54.43  ? 455 PHE   A CE2 1 
ATOM   3207 C  CZ  . PHE   A 1 455 ? 111.384 106.752 97.056  1.00 54.43  ? 455 PHE   A CZ  1 
ATOM   3208 N  N   . GLN   A 1 456 ? 115.701 108.907 99.950  1.00 55.88  ? 456 GLN   A N   1 
ATOM   3209 C  CA  . GLN   A 1 456 ? 116.148 107.751 100.722 1.00 55.88  ? 456 GLN   A CA  1 
ATOM   3210 C  C   . GLN   A 1 456 ? 116.029 108.008 102.218 1.00 55.88  ? 456 GLN   A C   1 
ATOM   3211 O  O   . GLN   A 1 456 ? 115.659 107.108 102.982 1.00 55.88  ? 456 GLN   A O   1 
ATOM   3212 C  CB  . GLN   A 1 456 ? 117.585 107.388 100.349 1.00 55.88  ? 456 GLN   A CB  1 
ATOM   3213 C  CG  . GLN   A 1 456 ? 118.221 106.341 101.254 1.00 55.88  ? 456 GLN   A CG  1 
ATOM   3214 C  CD  . GLN   A 1 456 ? 117.643 104.950 101.056 1.00 55.88  ? 456 GLN   A CD  1 
ATOM   3215 O  OE1 . GLN   A 1 456 ? 116.490 104.687 101.395 1.00 55.88  ? 456 GLN   A OE1 1 
ATOM   3216 N  NE2 . GLN   A 1 456 ? 118.450 104.049 100.508 1.00 55.88  ? 456 GLN   A NE2 1 
ATOM   3217 N  N   . LEU   A 1 457 ? 116.340 109.230 102.655 1.00 55.79  ? 457 LEU   A N   1 
ATOM   3218 C  CA  . LEU   A 1 457 ? 116.148 109.587 104.058 1.00 55.79  ? 457 LEU   A CA  1 
ATOM   3219 C  C   . LEU   A 1 457 ? 114.682 109.462 104.459 1.00 55.79  ? 457 LEU   A C   1 
ATOM   3220 O  O   . LEU   A 1 457 ? 114.361 108.910 105.522 1.00 55.79  ? 457 LEU   A O   1 
ATOM   3221 C  CB  . LEU   A 1 457 ? 116.653 111.010 104.302 1.00 55.79  ? 457 LEU   A CB  1 
ATOM   3222 C  CG  . LEU   A 1 457 ? 116.614 111.554 105.730 1.00 55.79  ? 457 LEU   A CG  1 
ATOM   3223 C  CD1 . LEU   A 1 457 ? 117.536 110.754 106.632 1.00 55.79  ? 457 LEU   A CD1 1 
ATOM   3224 C  CD2 . LEU   A 1 457 ? 116.981 113.026 105.750 1.00 55.79  ? 457 LEU   A CD2 1 
ATOM   3225 N  N   . PHE   A 1 458 ? 113.778 109.965 103.613 1.00 58.09  ? 458 PHE   A N   1 
ATOM   3226 C  CA  . PHE   A 1 458 ? 112.348 109.826 103.872 1.00 58.09  ? 458 PHE   A CA  1 
ATOM   3227 C  C   . PHE   A 1 458 ? 111.944 108.360 103.952 1.00 58.09  ? 458 PHE   A C   1 
ATOM   3228 O  O   . PHE   A 1 458 ? 111.207 107.962 104.860 1.00 58.09  ? 458 PHE   A O   1 
ATOM   3229 C  CB  . PHE   A 1 458 ? 111.542 110.532 102.780 1.00 58.09  ? 458 PHE   A CB  1 
ATOM   3230 C  CG  . PHE   A 1 458 ? 111.174 111.955 103.107 1.00 58.09  ? 458 PHE   A CG  1 
ATOM   3231 C  CD1 . PHE   A 1 458 ? 110.044 112.236 103.856 1.00 58.09  ? 458 PHE   A CD1 1 
ATOM   3232 C  CD2 . PHE   A 1 458 ? 111.945 113.009 102.649 1.00 58.09  ? 458 PHE   A CD2 1 
ATOM   3233 C  CE1 . PHE   A 1 458 ? 109.697 113.540 104.151 1.00 58.09  ? 458 PHE   A CE1 1 
ATOM   3234 C  CE2 . PHE   A 1 458 ? 111.602 114.314 102.942 1.00 58.09  ? 458 PHE   A CE2 1 
ATOM   3235 C  CZ  . PHE   A 1 458 ? 110.477 114.580 103.694 1.00 58.09  ? 458 PHE   A CZ  1 
ATOM   3236 N  N   . ASP   A 1 459 ? 112.432 107.543 103.018 1.00 60.13  ? 459 ASP   A N   1 
ATOM   3237 C  CA  . ASP   A 1 459 ? 112.073 106.129 102.998 1.00 60.13  ? 459 ASP   A CA  1 
ATOM   3238 C  C   . ASP   A 1 459 ? 112.541 105.423 104.262 1.00 60.13  ? 459 ASP   A C   1 
ATOM   3239 O  O   . ASP   A 1 459 ? 111.812 104.610 104.840 1.00 60.13  ? 459 ASP   A O   1 
ATOM   3240 C  CB  . ASP   A 1 459 ? 112.667 105.457 101.761 1.00 60.13  ? 459 ASP   A CB  1 
ATOM   3241 C  CG  . ASP   A 1 459 ? 111.869 104.249 101.315 1.00 60.13  ? 459 ASP   A CG  1 
ATOM   3242 O  OD1 . ASP   A 1 459 ? 110.717 104.096 101.772 1.00 60.13  ? 459 ASP   A OD1 1 
ATOM   3243 O  OD2 . ASP   A 1 459 ? 112.396 103.450 100.513 1.00 60.13  ? 459 ASP   A OD2 1 
ATOM   3244 N  N   . TYR   A 1 460 ? 113.764 105.720 104.706 1.00 61.06  ? 460 TYR   A N   1 
ATOM   3245 C  CA  . TYR   A 1 460 ? 114.300 105.026 105.871 1.00 61.06  ? 460 TYR   A CA  1 
ATOM   3246 C  C   . TYR   A 1 460 ? 113.616 105.469 107.157 1.00 61.06  ? 460 TYR   A C   1 
ATOM   3247 O  O   . TYR   A 1 460 ? 113.287 104.633 108.006 1.00 61.06  ? 460 TYR   A O   1 
ATOM   3248 C  CB  . TYR   A 1 460 ? 115.809 105.238 105.976 1.00 61.06  ? 460 TYR   A CB  1 
ATOM   3249 C  CG  . TYR   A 1 460 ? 116.482 104.226 106.874 1.00 61.06  ? 460 TYR   A CG  1 
ATOM   3250 C  CD1 . TYR   A 1 460 ? 116.865 102.984 106.386 1.00 61.06  ? 460 TYR   A CD1 1 
ATOM   3251 C  CD2 . TYR   A 1 460 ? 116.716 104.503 108.213 1.00 61.06  ? 460 TYR   A CD2 1 
ATOM   3252 C  CE1 . TYR   A 1 460 ? 117.472 102.052 107.204 1.00 61.06  ? 460 TYR   A CE1 1 
ATOM   3253 C  CE2 . TYR   A 1 460 ? 117.323 103.576 109.039 1.00 61.06  ? 460 TYR   A CE2 1 
ATOM   3254 C  CZ  . TYR   A 1 460 ? 117.699 102.353 108.528 1.00 61.06  ? 460 TYR   A CZ  1 
ATOM   3255 O  OH  . TYR   A 1 460 ? 118.304 101.425 109.345 1.00 61.06  ? 460 TYR   A OH  1 
ATOM   3256 N  N   . TYR   A 1 461 ? 113.392 106.773 107.330 1.00 57.06  ? 461 TYR   A N   1 
ATOM   3257 C  CA  . TYR   A 1 461 ? 112.922 107.283 108.614 1.00 57.06  ? 461 TYR   A CA  1 
ATOM   3258 C  C   . TYR   A 1 461 ? 111.421 107.555 108.632 1.00 57.06  ? 461 TYR   A C   1 
ATOM   3259 O  O   . TYR   A 1 461 ? 110.709 107.040 109.498 1.00 57.06  ? 461 TYR   A O   1 
ATOM   3260 C  CB  . TYR   A 1 461 ? 113.711 108.545 108.986 1.00 57.06  ? 461 TYR   A CB  1 
ATOM   3261 C  CG  . TYR   A 1 461 ? 115.083 108.238 109.538 1.00 57.06  ? 461 TYR   A CG  1 
ATOM   3262 C  CD1 . TYR   A 1 461 ? 116.154 107.997 108.691 1.00 57.06  ? 461 TYR   A CD1 1 
ATOM   3263 C  CD2 . TYR   A 1 461 ? 115.302 108.171 110.906 1.00 57.06  ? 461 TYR   A CD2 1 
ATOM   3264 C  CE1 . TYR   A 1 461 ? 117.407 107.709 109.190 1.00 57.06  ? 461 TYR   A CE1 1 
ATOM   3265 C  CE2 . TYR   A 1 461 ? 116.551 107.883 111.414 1.00 57.06  ? 461 TYR   A CE2 1 
ATOM   3266 C  CZ  . TYR   A 1 461 ? 117.599 107.652 110.552 1.00 57.06  ? 461 TYR   A CZ  1 
ATOM   3267 O  OH  . TYR   A 1 461 ? 118.846 107.365 111.055 1.00 57.06  ? 461 TYR   A OH  1 
ATOM   3268 N  N   . ALA   A 1 462 ? 110.927 108.361 107.697 1.00 59.44  ? 462 ALA   A N   1 
ATOM   3269 C  CA  . ALA   A 1 462 ? 109.526 108.761 107.717 1.00 59.44  ? 462 ALA   A CA  1 
ATOM   3270 C  C   . ALA   A 1 462 ? 108.620 107.591 107.351 1.00 59.44  ? 462 ALA   A C   1 
ATOM   3271 O  O   . ALA   A 1 462 ? 108.893 106.854 106.398 1.00 59.44  ? 462 ALA   A O   1 
ATOM   3272 C  CB  . ALA   A 1 462 ? 109.298 109.924 106.754 1.00 59.44  ? 462 ALA   A CB  1 
ATOM   3273 N  N   . ALA   A 1 463 ? 107.540 107.430 108.116 1.00 58.91  ? 463 ALA   A N   1 
ATOM   3274 C  CA  . ALA   A 1 463 ? 106.500 106.437 107.844 1.00 58.91  ? 463 ALA   A CA  1 
ATOM   3275 C  C   . ALA   A 1 463 ? 107.069 105.021 107.788 1.00 58.91  ? 463 ALA   A C   1 
ATOM   3276 O  O   . ALA   A 1 463 ? 106.635 104.181 106.997 1.00 58.91  ? 463 ALA   A O   1 
ATOM   3277 C  CB  . ALA   A 1 463 ? 105.749 106.773 106.556 1.00 58.91  ? 463 ALA   A CB  1 
ATOM   3278 N  N   . SER   A 1 464 ? 108.050 104.759 108.648 1.00 61.77  ? 464 SER   A N   1 
ATOM   3279 C  CA  . SER   A 1 464 ? 108.656 103.439 108.765 1.00 61.77  ? 464 SER   A CA  1 
ATOM   3280 C  C   . SER   A 1 464 ? 109.571 103.435 109.979 1.00 61.77  ? 464 SER   A C   1 
ATOM   3281 O  O   . SER   A 1 464 ? 109.902 104.487 110.532 1.00 61.77  ? 464 SER   A O   1 
ATOM   3282 C  CB  . SER   A 1 464 ? 109.442 103.054 107.507 1.00 61.77  ? 464 SER   A CB  1 
ATOM   3283 O  OG  . SER   A 1 464 ? 109.926 101.726 107.596 1.00 61.77  ? 464 SER   A OG  1 
ATOM   3284 N  N   . GLY   A 1 465 ? 109.978 102.236 110.382 1.00 64.74  ? 465 GLY   A N   1 
ATOM   3285 C  CA  . GLY   A 1 465 ? 110.925 102.092 111.468 1.00 64.74  ? 465 GLY   A CA  1 
ATOM   3286 C  C   . GLY   A 1 465 ? 110.324 102.196 112.853 1.00 64.74  ? 465 GLY   A C   1 
ATOM   3287 O  O   . GLY   A 1 465 ? 109.389 101.467 113.194 1.00 64.74  ? 465 GLY   A O   1 
ATOM   3288 N  N   . VAL   A 1 466 ? 110.862 103.110 113.661 1.00 66.79  ? 466 VAL   A N   1 
ATOM   3289 C  CA  . VAL   A 1 466 ? 110.513 103.160 115.079 1.00 66.79  ? 466 VAL   A CA  1 
ATOM   3290 C  C   . VAL   A 1 466 ? 109.101 103.702 115.277 1.00 66.79  ? 466 VAL   A C   1 
ATOM   3291 O  O   . VAL   A 1 466 ? 108.411 103.333 116.233 1.00 66.79  ? 466 VAL   A O   1 
ATOM   3292 C  CB  . VAL   A 1 466 ? 111.553 103.984 115.857 1.00 66.79  ? 466 VAL   A CB  1 
ATOM   3293 C  CG1 . VAL   A 1 466 ? 112.873 103.239 115.911 1.00 66.79  ? 466 VAL   A CG1 1 
ATOM   3294 C  CG2 . VAL   A 1 466 ? 111.746 105.334 115.198 1.00 66.79  ? 466 VAL   A CG2 1 
ATOM   3295 N  N   . CYS   A 1 467 ? 108.657 104.604 114.397 1.00 65.59  ? 467 CYS   A N   1 
ATOM   3296 C  CA  . CYS   A 1 467 ? 107.344 105.218 114.582 1.00 65.59  ? 467 CYS   A CA  1 
ATOM   3297 C  C   . CYS   A 1 467 ? 106.213 104.204 114.456 1.00 65.59  ? 467 CYS   A C   1 
ATOM   3298 O  O   . CYS   A 1 467 ? 105.277 104.210 115.268 1.00 65.59  ? 467 CYS   A O   1 
ATOM   3299 C  CB  . CYS   A 1 467 ? 107.147 106.356 113.579 1.00 65.59  ? 467 CYS   A CB  1 
ATOM   3300 S  SG  . CYS   A 1 467 ? 107.425 105.901 111.855 1.00 65.59  ? 467 CYS   A SG  1 
ATOM   3301 N  N   . LEU   A 1 468 ? 106.278 103.328 113.451 1.00 64.19  ? 468 LEU   A N   1 
ATOM   3302 C  CA  . LEU   A 1 468 ? 105.241 102.318 113.271 1.00 64.19  ? 468 LEU   A CA  1 
ATOM   3303 C  C   . LEU   A 1 468 ? 105.189 101.361 114.455 1.00 64.19  ? 468 LEU   A C   1 
ATOM   3304 O  O   . LEU   A 1 468 ? 104.105 101.040 114.956 1.00 64.19  ? 468 LEU   A O   1 
ATOM   3305 C  CB  . LEU   A 1 468 ? 105.477 101.546 111.970 1.00 64.19  ? 468 LEU   A CB  1 
ATOM   3306 C  CG  . LEU   A 1 468 ? 105.184 102.262 110.650 1.00 64.19  ? 468 LEU   A CG  1 
ATOM   3307 C  CD1 . LEU   A 1 468 ? 105.156 101.269 109.502 1.00 64.19  ? 468 LEU   A CD1 1 
ATOM   3308 C  CD2 . LEU   A 1 468 ? 103.876 103.031 110.726 1.00 64.19  ? 468 LEU   A CD2 1 
ATOM   3309 N  N   . LEU   A 1 469 ? 106.355 100.896 114.913 1.00 60.52  ? 469 LEU   A N   1 
ATOM   3310 C  CA  . LEU   A 1 469 ? 106.394 100.008 116.068 1.00 60.52  ? 469 LEU   A CA  1 
ATOM   3311 C  C   . LEU   A 1 469 ? 105.856 100.703 117.309 1.00 60.52  ? 469 LEU   A C   1 
ATOM   3312 O  O   . LEU   A 1 469 ? 105.106 100.105 118.086 1.00 60.52  ? 469 LEU   A O   1 
ATOM   3313 C  CB  . LEU   A 1 469 ? 107.820 99.518  116.307 1.00 60.52  ? 469 LEU   A CB  1 
ATOM   3314 C  CG  . LEU   A 1 469 ? 108.447 98.711  115.172 1.00 60.52  ? 469 LEU   A CG  1 
ATOM   3315 C  CD1 . LEU   A 1 469 ? 109.826 98.218  115.569 1.00 60.52  ? 469 LEU   A CD1 1 
ATOM   3316 C  CD2 . LEU   A 1 469 ? 107.549 97.549  114.788 1.00 60.52  ? 469 LEU   A CD2 1 
ATOM   3317 N  N   . TRP   A 1 470 ? 106.222 101.970 117.503 1.00 64.39  ? 470 TRP   A N   1 
ATOM   3318 C  CA  . TRP   A 1 470 ? 105.709 102.750 118.624 1.00 64.39  ? 470 TRP   A CA  1 
ATOM   3319 C  C   . TRP   A 1 470 ? 104.186 102.790 118.614 1.00 64.39  ? 470 TRP   A C   1 
ATOM   3320 O  O   . TRP   A 1 470 ? 103.528 102.447 119.609 1.00 64.39  ? 470 TRP   A O   1 
ATOM   3321 C  CB  . TRP   A 1 470 ? 106.289 104.165 118.546 1.00 64.39  ? 470 TRP   A CB  1 
ATOM   3322 C  CG  . TRP   A 1 470 ? 106.100 105.007 119.764 1.00 64.39  ? 470 TRP   A CG  1 
ATOM   3323 C  CD1 . TRP   A 1 470 ? 105.001 105.747 120.084 1.00 64.39  ? 470 TRP   A CD1 1 
ATOM   3324 C  CD2 . TRP   A 1 470 ? 107.053 105.230 120.809 1.00 64.39  ? 470 TRP   A CD2 1 
ATOM   3325 N  NE1 . TRP   A 1 470 ? 105.202 106.403 121.274 1.00 64.39  ? 470 TRP   A NE1 1 
ATOM   3326 C  CE2 . TRP   A 1 470 ? 106.455 106.103 121.738 1.00 64.39  ? 470 TRP   A CE2 1 
ATOM   3327 C  CE3 . TRP   A 1 470 ? 108.349 104.770 121.053 1.00 64.39  ? 470 TRP   A CE3 1 
ATOM   3328 C  CZ2 . TRP   A 1 470 ? 107.109 106.523 122.893 1.00 64.39  ? 470 TRP   A CZ2 1 
ATOM   3329 C  CZ3 . TRP   A 1 470 ? 108.996 105.189 122.199 1.00 64.39  ? 470 TRP   A CZ3 1 
ATOM   3330 C  CH2 . TRP   A 1 470 ? 108.376 106.056 123.104 1.00 64.39  ? 470 TRP   A CH2 1 
ATOM   3331 N  N   . VAL   A 1 471 ? 103.609 103.184 117.476 1.00 65.13  ? 471 VAL   A N   1 
ATOM   3332 C  CA  . VAL   A 1 471 ? 102.161 103.353 117.396 1.00 65.13  ? 471 VAL   A CA  1 
ATOM   3333 C  C   . VAL   A 1 471 ? 101.452 102.017 117.580 1.00 65.13  ? 471 VAL   A C   1 
ATOM   3334 O  O   . VAL   A 1 471 ? 100.459 101.922 118.311 1.00 65.13  ? 471 VAL   A O   1 
ATOM   3335 C  CB  . VAL   A 1 471 ? 101.777 104.027 116.065 1.00 65.13  ? 471 VAL   A CB  1 
ATOM   3336 C  CG1 . VAL   A 1 471 ? 100.270 104.076 115.912 1.00 65.13  ? 471 VAL   A CG1 1 
ATOM   3337 C  CG2 . VAL   A 1 471 ? 102.363 105.427 115.995 1.00 65.13  ? 471 VAL   A CG2 1 
ATOM   3338 N  N   . ALA   A 1 472 ? 101.949 100.964 116.927 1.00 62.29  ? 472 ALA   A N   1 
ATOM   3339 C  CA  . ALA   A 1 472 ? 101.299 99.660  117.021 1.00 62.29  ? 472 ALA   A CA  1 
ATOM   3340 C  C   . ALA   A 1 472 ? 101.392 99.088  118.430 1.00 62.29  ? 472 ALA   A C   1 
ATOM   3341 O  O   . ALA   A 1 472 ? 100.424 98.504  118.939 1.00 62.29  ? 472 ALA   A O   1 
ATOM   3342 C  CB  . ALA   A 1 472 ? 101.914 98.699  116.012 1.00 62.29  ? 472 ALA   A CB  1 
ATOM   3343 N  N   . PHE   A 1 473 ? 102.558 99.222  119.069 1.00 64.41  ? 473 PHE   A N   1 
ATOM   3344 C  CA  . PHE   A 1 473 ? 102.704 98.748  120.438 1.00 64.41  ? 473 PHE   A CA  1 
ATOM   3345 C  C   . PHE   A 1 473 ? 101.739 99.467  121.362 1.00 64.41  ? 473 PHE   A C   1 
ATOM   3346 O  O   . PHE   A 1 473 ? 101.096 98.837  122.207 1.00 64.41  ? 473 PHE   A O   1 
ATOM   3347 C  CB  . PHE   A 1 473 ? 104.144 98.937  120.917 1.00 64.41  ? 473 PHE   A CB  1 
ATOM   3348 C  CG  . PHE   A 1 473 ? 104.300 98.882  122.415 1.00 64.41  ? 473 PHE   A CG  1 
ATOM   3349 C  CD1 . PHE   A 1 473 ? 104.459 97.670  123.063 1.00 64.41  ? 473 PHE   A CD1 1 
ATOM   3350 C  CD2 . PHE   A 1 473 ? 104.300 100.042 123.173 1.00 64.41  ? 473 PHE   A CD2 1 
ATOM   3351 C  CE1 . PHE   A 1 473 ? 104.604 97.615  124.435 1.00 64.41  ? 473 PHE   A CE1 1 
ATOM   3352 C  CE2 . PHE   A 1 473 ? 104.442 99.990  124.546 1.00 64.41  ? 473 PHE   A CE2 1 
ATOM   3353 C  CZ  . PHE   A 1 473 ? 104.595 98.775  125.176 1.00 64.41  ? 473 PHE   A CZ  1 
ATOM   3354 N  N   . PHE   A 1 474 ? 101.619 100.789 121.217 1.00 66.79  ? 474 PHE   A N   1 
ATOM   3355 C  CA  . PHE   A 1 474 ? 100.677 101.504 122.070 1.00 66.79  ? 474 PHE   A CA  1 
ATOM   3356 C  C   . PHE   A 1 474 ? 99.237  101.088 121.793 1.00 66.79  ? 474 PHE   A C   1 
ATOM   3357 O  O   . PHE   A 1 474 ? 98.448  100.948 122.735 1.00 66.79  ? 474 PHE   A O   1 
ATOM   3358 C  CB  . PHE   A 1 474 ? 100.857 103.011 121.909 1.00 66.79  ? 474 PHE   A CB  1 
ATOM   3359 C  CG  . PHE   A 1 474 ? 101.722 103.622 122.969 1.00 66.79  ? 474 PHE   A CG  1 
ATOM   3360 C  CD1 . PHE   A 1 474 ? 103.090 103.411 122.969 1.00 66.79  ? 474 PHE   A CD1 1 
ATOM   3361 C  CD2 . PHE   A 1 474 ? 101.167 104.385 123.978 1.00 66.79  ? 474 PHE   A CD2 1 
ATOM   3362 C  CE1 . PHE   A 1 474 ? 103.889 103.962 123.947 1.00 66.79  ? 474 PHE   A CE1 1 
ATOM   3363 C  CE2 . PHE   A 1 474 ? 101.962 104.939 124.960 1.00 66.79  ? 474 PHE   A CE2 1 
ATOM   3364 C  CZ  . PHE   A 1 474 ? 103.325 104.727 124.944 1.00 66.79  ? 474 PHE   A CZ  1 
ATOM   3365 N  N   . GLU   A 1 475 ? 98.884  100.871 120.523 1.00 73.07  ? 475 GLU   A N   1 
ATOM   3366 C  CA  . GLU   A 1 475 ? 97.535  100.417 120.188 1.00 73.07  ? 475 GLU   A CA  1 
ATOM   3367 C  C   . GLU   A 1 475 ? 97.214  99.096  120.872 1.00 73.07  ? 475 GLU   A C   1 
ATOM   3368 O  O   . GLU   A 1 475 ? 96.189  98.963  121.556 1.00 73.07  ? 475 GLU   A O   1 
ATOM   3369 C  CB  . GLU   A 1 475 ? 97.397  100.265 118.672 1.00 73.07  ? 475 GLU   A CB  1 
ATOM   3370 C  CG  . GLU   A 1 475 ? 96.934  101.506 117.947 1.00 73.07  ? 475 GLU   A CG  1 
ATOM   3371 C  CD  . GLU   A 1 475 ? 96.535  101.222 116.513 1.00 73.07  ? 475 GLU   A CD  1 
ATOM   3372 O  OE1 . GLU   A 1 475 ? 96.718  100.072 116.062 1.00 73.07  ? 475 GLU   A OE1 1 
ATOM   3373 O  OE2 . GLU   A 1 475 ? 96.040  102.147 115.836 1.00 73.07  ? 475 GLU   A OE2 1 
ATOM   3374 N  N   . CYS   A 1 476 ? 98.085  98.101  120.692 1.00 68.56  ? 476 CYS   A N   1 
ATOM   3375 C  CA  . CYS   A 1 476 ? 97.840  96.796  121.294 1.00 68.56  ? 476 CYS   A CA  1 
ATOM   3376 C  C   . CYS   A 1 476 ? 97.820  96.891  122.813 1.00 68.56  ? 476 CYS   A C   1 
ATOM   3377 O  O   . CYS   A 1 476 ? 96.957  96.292  123.467 1.00 68.56  ? 476 CYS   A O   1 
ATOM   3378 C  CB  . CYS   A 1 476 ? 98.891  95.791  120.827 1.00 68.56  ? 476 CYS   A CB  1 
ATOM   3379 S  SG  . CYS   A 1 476 ? 98.621  95.170  119.155 1.00 68.56  ? 476 CYS   A SG  1 
ATOM   3380 N  N   . PHE   A 1 477 ? 98.743  97.664  123.390 1.00 69.99  ? 477 PHE   A N   1 
ATOM   3381 C  CA  . PHE   A 1 477 ? 98.802  97.801  124.839 1.00 69.99  ? 477 PHE   A CA  1 
ATOM   3382 C  C   . PHE   A 1 477 ? 97.502  98.367  125.390 1.00 69.99  ? 477 PHE   A C   1 
ATOM   3383 O  O   . PHE   A 1 477 ? 96.926  97.814  126.334 1.00 69.99  ? 477 PHE   A O   1 
ATOM   3384 C  CB  . PHE   A 1 477 ? 99.988  98.684  125.231 1.00 69.99  ? 477 PHE   A CB  1 
ATOM   3385 C  CG  . PHE   A 1 477 ? 100.021 99.048  126.688 1.00 69.99  ? 477 PHE   A CG  1 
ATOM   3386 C  CD1 . PHE   A 1 477 ? 100.606 98.202  127.612 1.00 69.99  ? 477 PHE   A CD1 1 
ATOM   3387 C  CD2 . PHE   A 1 477 ? 99.478  100.243 127.132 1.00 69.99  ? 477 PHE   A CD2 1 
ATOM   3388 C  CE1 . PHE   A 1 477 ? 100.640 98.533  128.951 1.00 69.99  ? 477 PHE   A CE1 1 
ATOM   3389 C  CE2 . PHE   A 1 477 ? 99.509  100.578 128.469 1.00 69.99  ? 477 PHE   A CE2 1 
ATOM   3390 C  CZ  . PHE   A 1 477 ? 100.091 99.723  129.380 1.00 69.99  ? 477 PHE   A CZ  1 
ATOM   3391 N  N   . VAL   A 1 478 ? 97.020  99.473  124.817 1.00 73.65  ? 478 VAL   A N   1 
ATOM   3392 C  CA  . VAL   A 1 478 ? 95.809  100.089 125.354 1.00 73.65  ? 478 VAL   A CA  1 
ATOM   3393 C  C   . VAL   A 1 478 ? 94.617  99.157  125.171 1.00 73.65  ? 478 VAL   A C   1 
ATOM   3394 O  O   . VAL   A 1 478 ? 93.882  98.877  126.128 1.00 73.65  ? 478 VAL   A O   1 
ATOM   3395 C  CB  . VAL   A 1 478 ? 95.564  101.479 124.731 1.00 73.65  ? 478 VAL   A CB  1 
ATOM   3396 C  CG1 . VAL   A 1 478 ? 95.448  101.421 123.221 1.00 73.65  ? 478 VAL   A CG1 1 
ATOM   3397 C  CG2 . VAL   A 1 478 ? 94.313  102.104 125.323 1.00 73.65  ? 478 VAL   A CG2 1 
ATOM   3398 N  N   . ILE   A 1 479 ? 94.448  98.602  123.965 1.00 74.44  ? 479 ILE   A N   1 
ATOM   3399 C  CA  . ILE   A 1 479 ? 93.258  97.801  123.687 1.00 74.44  ? 479 ILE   A CA  1 
ATOM   3400 C  C   . ILE   A 1 479 ? 93.247  96.543  124.548 1.00 74.44  ? 479 ILE   A C   1 
ATOM   3401 O  O   . ILE   A 1 479 ? 92.183  96.011  124.884 1.00 74.44  ? 479 ILE   A O   1 
ATOM   3402 C  CB  . ILE   A 1 479 ? 93.167  97.463  122.188 1.00 74.44  ? 479 ILE   A CB  1 
ATOM   3403 C  CG1 . ILE   A 1 479 ? 91.776  96.926  121.850 1.00 74.44  ? 479 ILE   A CG1 1 
ATOM   3404 C  CG2 . ILE   A 1 479 ? 94.214  96.440  121.804 1.00 74.44  ? 479 ILE   A CG2 1 
ATOM   3405 C  CD1 . ILE   A 1 479 ? 90.672  97.937  122.038 1.00 74.44  ? 479 ILE   A CD1 1 
ATOM   3406 N  N   . ALA   A 1 480 ? 94.430  96.053  124.929 1.00 75.03  ? 480 ALA   A N   1 
ATOM   3407 C  CA  . ALA   A 1 480 ? 94.482  94.812  125.691 1.00 75.03  ? 480 ALA   A CA  1 
ATOM   3408 C  C   . ALA   A 1 480 ? 94.360  95.063  127.188 1.00 75.03  ? 480 ALA   A C   1 
ATOM   3409 O  O   . ALA   A 1 480 ? 93.691  94.299  127.893 1.00 75.03  ? 480 ALA   A O   1 
ATOM   3410 C  CB  . ALA   A 1 480 ? 95.774  94.061  125.377 1.00 75.03  ? 480 ALA   A CB  1 
ATOM   3411 N  N   . TRP   A 1 481 ? 94.992  96.119  127.699 1.00 74.67  ? 481 TRP   A N   1 
ATOM   3412 C  CA  . TRP   A 1 481 ? 95.142  96.286  129.136 1.00 74.67  ? 481 TRP   A CA  1 
ATOM   3413 C  C   . TRP   A 1 481 ? 94.329  97.441  129.710 1.00 74.67  ? 481 TRP   A C   1 
ATOM   3414 O  O   . TRP   A 1 481 ? 94.495  97.762  130.891 1.00 74.67  ? 481 TRP   A O   1 
ATOM   3415 C  CB  . TRP   A 1 481 ? 96.620  96.469  129.488 1.00 74.67  ? 481 TRP   A CB  1 
ATOM   3416 C  CG  . TRP   A 1 481 ? 97.474  95.296  129.112 1.00 74.67  ? 481 TRP   A CG  1 
ATOM   3417 C  CD1 . TRP   A 1 481 ? 98.253  95.174  128.000 1.00 74.67  ? 481 TRP   A CD1 1 
ATOM   3418 C  CD2 . TRP   A 1 481 ? 97.632  94.077  129.847 1.00 74.67  ? 481 TRP   A CD2 1 
ATOM   3419 N  NE1 . TRP   A 1 481 ? 98.888  93.957  127.996 1.00 74.67  ? 481 TRP   A NE1 1 
ATOM   3420 C  CE2 . TRP   A 1 481 ? 98.524  93.264  129.120 1.00 74.67  ? 481 TRP   A CE2 1 
ATOM   3421 C  CE3 . TRP   A 1 481 ? 97.107  93.594  131.050 1.00 74.67  ? 481 TRP   A CE3 1 
ATOM   3422 C  CZ2 . TRP   A 1 481 ? 98.902  91.996  129.555 1.00 74.67  ? 481 TRP   A CZ2 1 
ATOM   3423 C  CZ3 . TRP   A 1 481 ? 97.484  92.335  131.480 1.00 74.67  ? 481 TRP   A CZ3 1 
ATOM   3424 C  CH2 . TRP   A 1 481 ? 98.372  91.551  130.735 1.00 74.67  ? 481 TRP   A CH2 1 
ATOM   3425 N  N   . ILE   A 1 482 ? 93.459  98.076  128.925 1.00 79.18  ? 482 ILE   A N   1 
ATOM   3426 C  CA  . ILE   A 1 482 ? 92.573  99.078  129.507 1.00 79.18  ? 482 ILE   A CA  1 
ATOM   3427 C  C   . ILE   A 1 482 ? 91.124  98.721  129.206 1.00 79.18  ? 482 ILE   A C   1 
ATOM   3428 O  O   . ILE   A 1 482 ? 90.317  98.536  130.124 1.00 79.18  ? 482 ILE   A O   1 
ATOM   3429 C  CB  . ILE   A 1 482 ? 92.915  100.493 129.006 1.00 79.18  ? 482 ILE   A CB  1 
ATOM   3430 C  CG1 . ILE   A 1 482 ? 94.302  100.905 129.501 1.00 79.18  ? 482 ILE   A CG1 1 
ATOM   3431 C  CG2 . ILE   A 1 482 ? 91.868  101.488 129.474 1.00 79.18  ? 482 ILE   A CG2 1 
ATOM   3432 C  CD1 . ILE   A 1 482 ? 94.811  102.195 128.903 1.00 79.18  ? 482 ILE   A CD1 1 
ATOM   3433 N  N   . TYR   A 1 483 ? 90.783  98.624  127.920 1.00 83.19  ? 483 TYR   A N   1 
ATOM   3434 C  CA  . TYR   A 1 483 ? 89.415  98.276  127.548 1.00 83.19  ? 483 TYR   A CA  1 
ATOM   3435 C  C   . TYR   A 1 483 ? 89.118  96.814  127.862 1.00 83.19  ? 483 TYR   A C   1 
ATOM   3436 O  O   . TYR   A 1 483 ? 88.048  96.486  128.388 1.00 83.19  ? 483 TYR   A O   1 
ATOM   3437 C  CB  . TYR   A 1 483 ? 89.182  98.569  126.066 1.00 83.19  ? 483 TYR   A CB  1 
ATOM   3438 C  CG  . TYR   A 1 483 ? 87.754  98.348  125.625 1.00 83.19  ? 483 TYR   A CG  1 
ATOM   3439 C  CD1 . TYR   A 1 483 ? 86.731  99.156  126.102 1.00 83.19  ? 483 TYR   A CD1 1 
ATOM   3440 C  CD2 . TYR   A 1 483 ? 87.428  97.332  124.738 1.00 83.19  ? 483 TYR   A CD2 1 
ATOM   3441 C  CE1 . TYR   A 1 483 ? 85.423  98.960  125.706 1.00 83.19  ? 483 TYR   A CE1 1 
ATOM   3442 C  CE2 . TYR   A 1 483 ? 86.121  97.129  124.337 1.00 83.19  ? 483 TYR   A CE2 1 
ATOM   3443 C  CZ  . TYR   A 1 483 ? 85.124  97.946  124.824 1.00 83.19  ? 483 TYR   A CZ  1 
ATOM   3444 O  OH  . TYR   A 1 483 ? 83.821  97.749  124.429 1.00 83.19  ? 483 TYR   A OH  1 
ATOM   3445 N  N   . GLY   A 1 484 ? 90.055  95.923  127.550 1.00 85.15  ? 484 GLY   A N   1 
ATOM   3446 C  CA  . GLY   A 1 484 ? 89.883  94.512  127.831 1.00 85.15  ? 484 GLY   A CA  1 
ATOM   3447 C  C   . GLY   A 1 484 ? 89.416  93.711  126.634 1.00 85.15  ? 484 GLY   A C   1 
ATOM   3448 O  O   . GLY   A 1 484 ? 88.468  94.106  125.949 1.00 85.15  ? 484 GLY   A O   1 
ATOM   3449 N  N   . GLY   A 1 485 ? 90.077  92.584  126.368 1.00 88.32  ? 485 GLY   A N   1 
ATOM   3450 C  CA  . GLY   A 1 485 ? 89.665  91.743  125.255 1.00 88.32  ? 485 GLY   A CA  1 
ATOM   3451 C  C   . GLY   A 1 485 ? 88.312  91.095  125.480 1.00 88.32  ? 485 GLY   A C   1 
ATOM   3452 O  O   . GLY   A 1 485 ? 87.574  90.828  124.527 1.00 88.32  ? 485 GLY   A O   1 
ATOM   3453 N  N   . ASP   A 1 486 ? 87.971  90.827  126.742 1.00 91.54  ? 486 ASP   A N   1 
ATOM   3454 C  CA  . ASP   A 1 486 ? 86.688  90.222  127.074 1.00 91.54  ? 486 ASP   A CA  1 
ATOM   3455 C  C   . ASP   A 1 486 ? 85.531  91.118  126.650 1.00 91.54  ? 486 ASP   A C   1 
ATOM   3456 O  O   . ASP   A 1 486 ? 84.509  90.645  126.137 1.00 91.54  ? 486 ASP   A O   1 
ATOM   3457 C  CB  . ASP   A 1 486 ? 86.626  89.931  128.576 1.00 91.54  ? 486 ASP   A CB  1 
ATOM   3458 C  CG  . ASP   A 1 486 ? 85.371  89.183  128.973 1.00 91.54  ? 486 ASP   A CG  1 
ATOM   3459 O  OD1 . ASP   A 1 486 ? 85.296  87.964  128.710 1.00 91.54  ? 486 ASP   A OD1 1 
ATOM   3460 O  OD2 . ASP   A 1 486 ? 84.457  89.813  129.545 1.00 91.54  ? 486 ASP   A OD2 1 
ATOM   3461 N  N   . ASN   A 1 487 ? 85.684  92.426  126.865 1.00 90.44  ? 487 ASN   A N   1 
ATOM   3462 C  CA  . ASN   A 1 487 ? 84.658  93.373  126.443 1.00 90.44  ? 487 ASN   A CA  1 
ATOM   3463 C  C   . ASN   A 1 487 ? 84.462  93.326  124.934 1.00 90.44  ? 487 ASN   A C   1 
ATOM   3464 O  O   . ASN   A 1 487 ? 83.329  93.348  124.441 1.00 90.44  ? 487 ASN   A O   1 
ATOM   3465 C  CB  . ASN   A 1 487 ? 85.031  94.786  126.896 1.00 90.44  ? 487 ASN   A CB  1 
ATOM   3466 C  CG  . ASN   A 1 487 ? 84.769  95.013  128.372 1.00 90.44  ? 487 ASN   A CG  1 
ATOM   3467 O  OD1 . ASN   A 1 487 ? 83.848  95.738  128.747 1.00 90.44  ? 487 ASN   A OD1 1 
ATOM   3468 N  ND2 . ASN   A 1 487 ? 85.584  94.395  129.219 1.00 90.44  ? 487 ASN   A ND2 1 
ATOM   3469 N  N   . LEU   A 1 488 ? 85.561  93.255  124.180 1.00 90.29  ? 488 LEU   A N   1 
ATOM   3470 C  CA  . LEU   A 1 488 ? 85.448  93.178  122.727 1.00 90.29  ? 488 LEU   A CA  1 
ATOM   3471 C  C   . LEU   A 1 488 ? 84.802  91.871  122.283 1.00 90.29  ? 488 LEU   A C   1 
ATOM   3472 O  O   . LEU   A 1 488 ? 84.001  91.866  121.342 1.00 90.29  ? 488 LEU   A O   1 
ATOM   3473 C  CB  . LEU   A 1 488 ? 86.815  93.358  122.072 1.00 90.29  ? 488 LEU   A CB  1 
ATOM   3474 C  CG  . LEU   A 1 488 ? 87.228  94.820  121.892 1.00 90.29  ? 488 LEU   A CG  1 
ATOM   3475 C  CD1 . LEU   A 1 488 ? 88.579  94.929  121.213 1.00 90.29  ? 488 LEU   A CD1 1 
ATOM   3476 C  CD2 . LEU   A 1 488 ? 86.171  95.575  121.101 1.00 90.29  ? 488 LEU   A CD2 1 
ATOM   3477 N  N   . TYR   A 1 489 ? 85.137  90.752  122.931 1.00 86.56  ? 489 TYR   A N   1 
ATOM   3478 C  CA  . TYR   A 1 489 ? 84.473  89.495  122.595 1.00 86.56  ? 489 TYR   A CA  1 
ATOM   3479 C  C   . TYR   A 1 489 ? 82.973  89.578  122.844 1.00 86.56  ? 489 TYR   A C   1 
ATOM   3480 O  O   . TYR   A 1 489 ? 82.169  89.130  122.017 1.00 86.56  ? 489 TYR   A O   1 
ATOM   3481 C  CB  . TYR   A 1 489 ? 85.073  88.330  123.382 1.00 86.56  ? 489 TYR   A CB  1 
ATOM   3482 C  CG  . TYR   A 1 489 ? 86.385  87.810  122.853 1.00 86.56  ? 489 TYR   A CG  1 
ATOM   3483 C  CD1 . TYR   A 1 489 ? 86.847  88.169  121.596 1.00 86.56  ? 489 TYR   A CD1 1 
ATOM   3484 C  CD2 . TYR   A 1 489 ? 87.136  86.912  123.593 1.00 86.56  ? 489 TYR   A CD2 1 
ATOM   3485 C  CE1 . TYR   A 1 489 ? 88.041  87.675  121.109 1.00 86.56  ? 489 TYR   A CE1 1 
ATOM   3486 C  CE2 . TYR   A 1 489 ? 88.322  86.412  123.115 1.00 86.56  ? 489 TYR   A CE2 1 
ATOM   3487 C  CZ  . TYR   A 1 489 ? 88.773  86.795  121.875 1.00 86.56  ? 489 TYR   A CZ  1 
ATOM   3488 O  OH  . TYR   A 1 489 ? 89.962  86.286  121.411 1.00 86.56  ? 489 TYR   A OH  1 
ATOM   3489 N  N   . ASP   A 1 490 ? 82.576  90.143  123.985 1.00 94.25  ? 490 ASP   A N   1 
ATOM   3490 C  CA  . ASP   A 1 490 ? 81.151  90.287  124.269 1.00 94.25  ? 490 ASP   A CA  1 
ATOM   3491 C  C   . ASP   A 1 490 ? 80.480  91.203  123.253 1.00 94.25  ? 490 ASP   A C   1 
ATOM   3492 O  O   . ASP   A 1 490 ? 79.346  90.949  122.828 1.00 94.25  ? 490 ASP   A O   1 
ATOM   3493 C  CB  . ASP   A 1 490 ? 80.946  90.811  125.689 1.00 94.25  ? 490 ASP   A CB  1 
ATOM   3494 C  CG  . ASP   A 1 490 ? 81.649  89.963  126.729 1.00 94.25  ? 490 ASP   A CG  1 
ATOM   3495 O  OD1 . ASP   A 1 490 ? 81.972  88.795  126.425 1.00 94.25  ? 490 ASP   A OD1 1 
ATOM   3496 O  OD2 . ASP   A 1 490 ? 81.882  90.463  127.850 1.00 94.25  ? 490 ASP   A OD2 1 
ATOM   3497 N  N   . GLY   A 1 491 ? 81.165  92.275  122.853 1.00 95.45  ? 491 GLY   A N   1 
ATOM   3498 C  CA  . GLY   A 1 491 ? 80.594  93.189  121.877 1.00 95.45  ? 491 GLY   A CA  1 
ATOM   3499 C  C   . GLY   A 1 491 ? 80.446  92.569  120.499 1.00 95.45  ? 491 GLY   A C   1 
ATOM   3500 O  O   . GLY   A 1 491 ? 79.502  92.876  119.767 1.00 95.45  ? 491 GLY   A O   1 
ATOM   3501 N  N   . ILE   A 1 492 ? 81.391  91.708  120.114 1.00 95.39  ? 492 ILE   A N   1 
ATOM   3502 C  CA  . ILE   A 1 492 ? 81.361  91.150  118.765 1.00 95.39  ? 492 ILE   A CA  1 
ATOM   3503 C  C   . ILE   A 1 492 ? 80.621  89.821  118.685 1.00 95.39  ? 492 ILE   A C   1 
ATOM   3504 O  O   . ILE   A 1 492 ? 80.391  89.324  117.576 1.00 95.39  ? 492 ILE   A O   1 
ATOM   3505 C  CB  . ILE   A 1 492 ? 82.778  90.967  118.195 1.00 95.39  ? 492 ILE   A CB  1 
ATOM   3506 C  CG1 . ILE   A 1 492 ? 83.528  89.869  118.951 1.00 95.39  ? 492 ILE   A CG1 1 
ATOM   3507 C  CG2 . ILE   A 1 492 ? 83.542  92.281  118.229 1.00 95.39  ? 492 ILE   A CG2 1 
ATOM   3508 C  CD1 . ILE   A 1 492 ? 84.878  89.535  118.354 1.00 95.39  ? 492 ILE   A CD1 1 
ATOM   3509 N  N   . GLU   A 1 493 ? 80.255  89.218  119.820 1.00 99.56  ? 493 GLU   A N   1 
ATOM   3510 C  CA  . GLU   A 1 493 ? 79.519  87.958  119.762 1.00 99.56  ? 493 GLU   A CA  1 
ATOM   3511 C  C   . GLU   A 1 493 ? 78.188  88.119  119.039 1.00 99.56  ? 493 GLU   A C   1 
ATOM   3512 O  O   . GLU   A 1 493 ? 77.873  87.348  118.126 1.00 99.56  ? 493 GLU   A O   1 
ATOM   3513 C  CB  . GLU   A 1 493 ? 79.288  87.410  121.170 1.00 99.56  ? 493 GLU   A CB  1 
ATOM   3514 C  CG  . GLU   A 1 493 ? 78.437  86.148  121.194 1.00 99.56  ? 493 GLU   A CG  1 
ATOM   3515 C  CD  . GLU   A 1 493 ? 78.188  85.629  122.596 1.00 99.56  ? 493 GLU   A CD  1 
ATOM   3516 O  OE1 . GLU   A 1 493 ? 78.674  86.256  123.561 1.00 99.56  ? 493 GLU   A OE1 1 
ATOM   3517 O  OE2 . GLU   A 1 493 ? 77.505  84.592  122.733 1.00 99.56  ? 493 GLU   A OE2 1 
ATOM   3518 N  N   . ASP   A 1 494 ? 77.396  89.119  119.428 1.00 99.53  ? 494 ASP   A N   1 
ATOM   3519 C  CA  . ASP   A 1 494 ? 76.091  89.316  118.804 1.00 99.53  ? 494 ASP   A CA  1 
ATOM   3520 C  C   . ASP   A 1 494 ? 76.238  89.780  117.359 1.00 99.53  ? 494 ASP   A C   1 
ATOM   3521 O  O   . ASP   A 1 494 ? 75.471  89.371  116.480 1.00 99.53  ? 494 ASP   A O   1 
ATOM   3522 C  CB  . ASP   A 1 494 ? 75.265  90.312  119.619 1.00 99.53  ? 494 ASP   A CB  1 
ATOM   3523 C  CG  . ASP   A 1 494 ? 76.007  91.602  119.885 1.00 99.53  ? 494 ASP   A CG  1 
ATOM   3524 O  OD1 . ASP   A 1 494 ? 75.392  92.683  119.770 1.00 99.53  ? 494 ASP   A OD1 1 
ATOM   3525 O  OD2 . ASP   A 1 494 ? 77.206  91.531  120.220 1.00 99.53  ? 494 ASP   A OD2 1 
ATOM   3526 N  N   . MET   A 1 495 ? 77.218  90.648  117.096 1.00 96.81  ? 495 MET   A N   1 
ATOM   3527 C  CA  . MET   A 1 495 ? 77.426  91.134  115.735 1.00 96.81  ? 495 MET   A CA  1 
ATOM   3528 C  C   . MET   A 1 495 ? 77.839  90.001  114.804 1.00 96.81  ? 495 MET   A C   1 
ATOM   3529 O  O   . MET   A 1 495 ? 77.236  89.799  113.744 1.00 96.81  ? 495 MET   A O   1 
ATOM   3530 C  CB  . MET   A 1 495 ? 78.478  92.244  115.730 1.00 96.81  ? 495 MET   A CB  1 
ATOM   3531 C  CG  . MET   A 1 495 ? 78.161  93.413  116.645 1.00 96.81  ? 495 MET   A CG  1 
ATOM   3532 S  SD  . MET   A 1 495 ? 76.483  94.033  116.435 1.00 96.81  ? 495 MET   A SD  1 
ATOM   3533 C  CE  . MET   A 1 495 ? 76.543  95.511  117.442 1.00 96.81  ? 495 MET   A CE  1 
ATOM   3534 N  N   . ILE   A 1 496 ? 78.871  89.248  115.188 1.00 96.45  ? 496 ILE   A N   1 
ATOM   3535 C  CA  . ILE   A 1 496 ? 79.347  88.155  114.347 1.00 96.45  ? 496 ILE   A CA  1 
ATOM   3536 C  C   . ILE   A 1 496 ? 78.351  87.001  114.351 1.00 96.45  ? 496 ILE   A C   1 
ATOM   3537 O  O   . ILE   A 1 496 ? 78.046  86.420  113.302 1.00 96.45  ? 496 ILE   A O   1 
ATOM   3538 C  CB  . ILE   A 1 496 ? 80.744  87.701  114.809 1.00 96.45  ? 496 ILE   A CB  1 
ATOM   3539 C  CG1 . ILE   A 1 496 ? 81.810  88.690  114.336 1.00 96.45  ? 496 ILE   A CG1 1 
ATOM   3540 C  CG2 . ILE   A 1 496 ? 81.061  86.306  114.291 1.00 96.45  ? 496 ILE   A CG2 1 
ATOM   3541 C  CD1 . ILE   A 1 496 ? 82.151  88.565  112.874 1.00 96.45  ? 496 ILE   A CD1 1 
ATOM   3542 N  N   . GLY   A 1 497 ? 77.813  86.664  115.521 1.00 97.88  ? 497 GLY   A N   1 
ATOM   3543 C  CA  . GLY   A 1 497 ? 77.034  85.457  115.690 1.00 97.88  ? 497 GLY   A CA  1 
ATOM   3544 C  C   . GLY   A 1 497 ? 77.841  84.247  116.104 1.00 97.88  ? 497 GLY   A C   1 
ATOM   3545 O  O   . GLY   A 1 497 ? 77.256  83.183  116.344 1.00 97.88  ? 497 GLY   A O   1 
ATOM   3546 N  N   . TYR   A 1 498 ? 79.162  84.378  116.196 1.00 99.91  ? 498 TYR   A N   1 
ATOM   3547 C  CA  . TYR   A 1 498 ? 80.050  83.294  116.583 1.00 99.91  ? 498 TYR   A CA  1 
ATOM   3548 C  C   . TYR   A 1 498 ? 81.113  83.841  117.525 1.00 99.91  ? 498 TYR   A C   1 
ATOM   3549 O  O   . TYR   A 1 498 ? 81.485  85.015  117.449 1.00 99.91  ? 498 TYR   A O   1 
ATOM   3550 C  CB  . TYR   A 1 498 ? 80.695  82.642  115.350 1.00 99.91  ? 498 TYR   A CB  1 
ATOM   3551 C  CG  . TYR   A 1 498 ? 81.738  81.595  115.665 1.00 99.91  ? 498 TYR   A CG  1 
ATOM   3552 C  CD1 . TYR   A 1 498 ? 81.383  80.378  116.230 1.00 99.91  ? 498 TYR   A CD1 1 
ATOM   3553 C  CD2 . TYR   A 1 498 ? 83.079  81.819  115.383 1.00 99.91  ? 498 TYR   A CD2 1 
ATOM   3554 C  CE1 . TYR   A 1 498 ? 82.336  79.418  116.516 1.00 99.91  ? 498 TYR   A CE1 1 
ATOM   3555 C  CE2 . TYR   A 1 498 ? 84.039  80.866  115.663 1.00 99.91  ? 498 TYR   A CE2 1 
ATOM   3556 C  CZ  . TYR   A 1 498 ? 83.662  79.668  116.230 1.00 99.91  ? 498 TYR   A CZ  1 
ATOM   3557 O  OH  . TYR   A 1 498 ? 84.616  78.717  116.510 1.00 99.91  ? 498 TYR   A OH  1 
ATOM   3558 N  N   . ARG   A 1 499 ? 81.597  82.980  118.421 1.00 99.06  ? 499 ARG   A N   1 
ATOM   3559 C  CA  . ARG   A 1 499 ? 82.629  83.370  119.372 1.00 99.06  ? 499 ARG   A CA  1 
ATOM   3560 C  C   . ARG   A 1 499 ? 83.993  82.997  118.809 1.00 99.06  ? 499 ARG   A C   1 
ATOM   3561 O  O   . ARG   A 1 499 ? 84.275  81.800  118.643 1.00 99.06  ? 499 ARG   A O   1 
ATOM   3562 C  CB  . ARG   A 1 499 ? 82.407  82.691  120.716 1.00 99.06  ? 499 ARG   A CB  1 
ATOM   3563 C  CG  . ARG   A 1 499 ? 81.125  83.103  121.415 1.00 99.06  ? 499 ARG   A CG  1 
ATOM   3564 C  CD  . ARG   A 1 499 ? 81.362  84.277  122.350 1.00 99.06  ? 499 ARG   A CD  1 
ATOM   3565 N  NE  . ARG   A 1 499 ? 81.898  83.852  123.638 1.00 99.06  ? 499 ARG   A NE  1 
ATOM   3566 C  CZ  . ARG   A 1 499 ? 82.732  84.571  124.377 1.00 99.06  ? 499 ARG   A CZ  1 
ATOM   3567 N  NH1 . ARG   A 1 499 ? 83.139  85.769  123.993 1.00 99.06  ? 499 ARG   A NH1 1 
ATOM   3568 N  NH2 . ARG   A 1 499 ? 83.164  84.077  125.534 1.00 99.06  ? 499 ARG   A NH2 1 
ATOM   3569 N  N   . PRO   A 1 500 ? 84.861  83.961  118.504 1.00 90.90  ? 500 PRO   A N   1 
ATOM   3570 C  CA  . PRO   A 1 500 ? 86.177  83.625  117.952 1.00 90.90  ? 500 PRO   A CA  1 
ATOM   3571 C  C   . PRO   A 1 500 ? 87.009  82.830  118.947 1.00 90.90  ? 500 PRO   A C   1 
ATOM   3572 O  O   . PRO   A 1 500 ? 86.820  82.923  120.162 1.00 90.90  ? 500 PRO   A O   1 
ATOM   3573 C  CB  . PRO   A 1 500 ? 86.801  84.995  117.666 1.00 90.90  ? 500 PRO   A CB  1 
ATOM   3574 C  CG  . PRO   A 1 500 ? 85.634  85.916  117.521 1.00 90.90  ? 500 PRO   A CG  1 
ATOM   3575 C  CD  . PRO   A 1 500 ? 84.621  85.414  118.506 1.00 90.90  ? 500 PRO   A CD  1 
ATOM   3576 N  N   . GLY   A 1 501 ? 87.935  82.036  118.417 1.00 90.64  ? 501 GLY   A N   1 
ATOM   3577 C  CA  . GLY   A 1 501 ? 88.807  81.229  119.236 1.00 90.64  ? 501 GLY   A CA  1 
ATOM   3578 C  C   . GLY   A 1 501 ? 89.743  82.071  120.079 1.00 90.64  ? 501 GLY   A C   1 
ATOM   3579 O  O   . GLY   A 1 501 ? 89.928  83.268  119.838 1.00 90.64  ? 501 GLY   A O   1 
ATOM   3580 N  N   . PRO   A 1 502 ? 90.355  81.457  121.091 1.00 86.99  ? 502 PRO   A N   1 
ATOM   3581 C  CA  . PRO   A 1 502 ? 91.231  82.217  121.992 1.00 86.99  ? 502 PRO   A CA  1 
ATOM   3582 C  C   . PRO   A 1 502 ? 92.536  82.614  121.323 1.00 86.99  ? 502 PRO   A C   1 
ATOM   3583 O  O   . PRO   A 1 502 ? 93.600  82.075  121.647 1.00 86.99  ? 502 PRO   A O   1 
ATOM   3584 C  CB  . PRO   A 1 502 ? 91.469  81.243  123.151 1.00 86.99  ? 502 PRO   A CB  1 
ATOM   3585 C  CG  . PRO   A 1 502 ? 91.330  79.897  122.527 1.00 86.99  ? 502 PRO   A CG  1 
ATOM   3586 C  CD  . PRO   A 1 502 ? 90.275  80.034  121.463 1.00 86.99  ? 502 PRO   A CD  1 
ATOM   3587 N  N   . TRP   A 1 503 ? 92.463  83.557  120.385 1.00 82.91  ? 503 TRP   A N   1 
ATOM   3588 C  CA  . TRP   A 1 503 ? 93.633  84.001  119.647 1.00 82.91  ? 503 TRP   A CA  1 
ATOM   3589 C  C   . TRP   A 1 503 ? 93.669  85.513  119.463 1.00 82.91  ? 503 TRP   A C   1 
ATOM   3590 O  O   . TRP   A 1 503 ? 94.617  86.028  118.861 1.00 82.91  ? 503 TRP   A O   1 
ATOM   3591 C  CB  . TRP   A 1 503 ? 93.699  83.271  118.293 1.00 82.91  ? 503 TRP   A CB  1 
ATOM   3592 C  CG  . TRP   A 1 503 ? 94.873  83.605  117.431 1.00 82.91  ? 503 TRP   A CG  1 
ATOM   3593 C  CD1 . TRP   A 1 503 ? 96.186  83.364  117.708 1.00 82.91  ? 503 TRP   A CD1 1 
ATOM   3594 C  CD2 . TRP   A 1 503 ? 94.837  84.142  116.104 1.00 82.91  ? 503 TRP   A CD2 1 
ATOM   3595 N  NE1 . TRP   A 1 503 ? 96.974  83.773  116.662 1.00 82.91  ? 503 TRP   A NE1 1 
ATOM   3596 C  CE2 . TRP   A 1 503 ? 96.169  84.248  115.660 1.00 82.91  ? 503 TRP   A CE2 1 
ATOM   3597 C  CE3 . TRP   A 1 503 ? 93.809  84.563  115.257 1.00 82.91  ? 503 TRP   A CE3 1 
ATOM   3598 C  CZ2 . TRP   A 1 503 ? 96.500  84.759  114.408 1.00 82.91  ? 503 TRP   A CZ2 1 
ATOM   3599 C  CZ3 . TRP   A 1 503 ? 94.140  85.072  114.014 1.00 82.91  ? 503 TRP   A CZ3 1 
ATOM   3600 C  CH2 . TRP   A 1 503 ? 95.473  85.165  113.602 1.00 82.91  ? 503 TRP   A CH2 1 
ATOM   3601 N  N   . MET   A 1 504 ? 92.683  86.239  119.988 1.00 79.50  ? 504 MET   A N   1 
ATOM   3602 C  CA  . MET   A 1 504 ? 92.724  87.691  120.026 1.00 79.50  ? 504 MET   A CA  1 
ATOM   3603 C  C   . MET   A 1 504 ? 93.046  88.240  121.410 1.00 79.50  ? 504 MET   A C   1 
ATOM   3604 O  O   . MET   A 1 504 ? 93.229  89.453  121.548 1.00 79.50  ? 504 MET   A O   1 
ATOM   3605 C  CB  . MET   A 1 504 ? 91.391  88.283  119.545 1.00 79.50  ? 504 MET   A CB  1 
ATOM   3606 C  CG  . MET   A 1 504 ? 91.187  88.312  118.035 1.00 79.50  ? 504 MET   A CG  1 
ATOM   3607 S  SD  . MET   A 1 504 ? 92.623  88.892  117.110 1.00 79.50  ? 504 MET   A SD  1 
ATOM   3608 C  CE  . MET   A 1 504 ? 92.642  87.739  115.744 1.00 79.50  ? 504 MET   A CE  1 
ATOM   3609 N  N   . LYS   A 1 505 ? 93.123  87.391  122.437 1.00 77.03  ? 505 LYS   A N   1 
ATOM   3610 C  CA  . LYS   A 1 505 ? 93.535  87.836  123.761 1.00 77.03  ? 505 LYS   A CA  1 
ATOM   3611 C  C   . LYS   A 1 505 ? 95.002  87.569  124.054 1.00 77.03  ? 505 LYS   A C   1 
ATOM   3612 O  O   . LYS   A 1 505 ? 95.649  88.406  124.691 1.00 77.03  ? 505 LYS   A O   1 
ATOM   3613 C  CB  . LYS   A 1 505 ? 92.691  87.160  124.850 1.00 77.03  ? 505 LYS   A CB  1 
ATOM   3614 C  CG  . LYS   A 1 505 ? 91.202  87.401  124.737 1.00 77.03  ? 505 LYS   A CG  1 
ATOM   3615 C  CD  . LYS   A 1 505 ? 90.483  86.921  125.985 1.00 77.03  ? 505 LYS   A CD  1 
ATOM   3616 C  CE  . LYS   A 1 505 ? 90.662  85.424  126.180 1.00 77.03  ? 505 LYS   A CE  1 
ATOM   3617 N  NZ  . LYS   A 1 505 ? 90.025  84.622  125.101 1.00 77.03  ? 505 LYS   A NZ  1 
ATOM   3618 N  N   . TYR   A 1 506 ? 95.540  86.439  123.603 1.00 72.12  ? 506 TYR   A N   1 
ATOM   3619 C  CA  . TYR   A 1 506 ? 96.944  86.112  123.787 1.00 72.12  ? 506 TYR   A CA  1 
ATOM   3620 C  C   . TYR   A 1 506 ? 97.816  86.634  122.656 1.00 72.12  ? 506 TYR   A C   1 
ATOM   3621 O  O   . TYR   A 1 506 ? 99.023  86.378  122.650 1.00 72.12  ? 506 TYR   A O   1 
ATOM   3622 C  CB  . TYR   A 1 506 ? 97.118  84.598  123.929 1.00 72.12  ? 506 TYR   A CB  1 
ATOM   3623 C  CG  . TYR   A 1 506 ? 96.159  83.975  124.917 1.00 72.12  ? 506 TYR   A CG  1 
ATOM   3624 C  CD1 . TYR   A 1 506 ? 96.025  84.490  126.199 1.00 72.12  ? 506 TYR   A CD1 1 
ATOM   3625 C  CD2 . TYR   A 1 506 ? 95.389  82.873  124.570 1.00 72.12  ? 506 TYR   A CD2 1 
ATOM   3626 C  CE1 . TYR   A 1 506 ? 95.151  83.927  127.107 1.00 72.12  ? 506 TYR   A CE1 1 
ATOM   3627 C  CE2 . TYR   A 1 506 ? 94.512  82.303  125.473 1.00 72.12  ? 506 TYR   A CE2 1 
ATOM   3628 C  CZ  . TYR   A 1 506 ? 94.398  82.834  126.740 1.00 72.12  ? 506 TYR   A CZ  1 
ATOM   3629 O  OH  . TYR   A 1 506 ? 93.527  82.272  127.644 1.00 72.12  ? 506 TYR   A OH  1 
ATOM   3630 N  N   . SER   A 1 507 ? 97.230  87.353  121.697 1.00 69.99  ? 507 SER   A N   1 
ATOM   3631 C  CA  . SER   A 1 507 ? 97.982  88.020  120.646 1.00 69.99  ? 507 SER   A CA  1 
ATOM   3632 C  C   . SER   A 1 507 ? 97.923  89.536  120.723 1.00 69.99  ? 507 SER   A C   1 
ATOM   3633 O  O   . SER   A 1 507 ? 98.780  90.198  120.129 1.00 69.99  ? 507 SER   A O   1 
ATOM   3634 C  CB  . SER   A 1 507 ? 97.480  87.582  119.261 1.00 69.99  ? 507 SER   A CB  1 
ATOM   3635 O  OG  . SER   A 1 507 ? 97.936  88.471  118.259 1.00 69.99  ? 507 SER   A OG  1 
ATOM   3636 N  N   . TRP   A 1 508 ? 96.942  90.101  121.423 1.00 71.58  ? 508 TRP   A N   1 
ATOM   3637 C  CA  . TRP   A 1 508 ? 96.858  91.541  121.611 1.00 71.58  ? 508 TRP   A CA  1 
ATOM   3638 C  C   . TRP   A 1 508 ? 97.576  92.021  122.864 1.00 71.58  ? 508 TRP   A C   1 
ATOM   3639 O  O   . TRP   A 1 508 ? 97.820  93.225  122.997 1.00 71.58  ? 508 TRP   A O   1 
ATOM   3640 C  CB  . TRP   A 1 508 ? 95.391  91.979  121.685 1.00 71.58  ? 508 TRP   A CB  1 
ATOM   3641 C  CG  . TRP   A 1 508 ? 94.642  91.885  120.388 1.00 71.58  ? 508 TRP   A CG  1 
ATOM   3642 C  CD1 . TRP   A 1 508 ? 95.159  91.613  119.155 1.00 71.58  ? 508 TRP   A CD1 1 
ATOM   3643 C  CD2 . TRP   A 1 508 ? 93.231  92.051  120.203 1.00 71.58  ? 508 TRP   A CD2 1 
ATOM   3644 N  NE1 . TRP   A 1 508 ? 94.158  91.607  118.213 1.00 71.58  ? 508 TRP   A NE1 1 
ATOM   3645 C  CE2 . TRP   A 1 508 ? 92.965  91.870  118.832 1.00 71.58  ? 508 TRP   A CE2 1 
ATOM   3646 C  CE3 . TRP   A 1 508 ? 92.167  92.332  121.065 1.00 71.58  ? 508 TRP   A CE3 1 
ATOM   3647 C  CZ2 . TRP   A 1 508 ? 91.680  91.968  118.304 1.00 71.58  ? 508 TRP   A CZ2 1 
ATOM   3648 C  CZ3 . TRP   A 1 508 ? 90.895  92.425  120.539 1.00 71.58  ? 508 TRP   A CZ3 1 
ATOM   3649 C  CH2 . TRP   A 1 508 ? 90.661  92.245  119.172 1.00 71.58  ? 508 TRP   A CH2 1 
ATOM   3650 N  N   . ALA   A 1 509 ? 97.923  91.114  123.781 1.00 69.50  ? 509 ALA   A N   1 
ATOM   3651 C  CA  . ALA   A 1 509 ? 98.469  91.496  125.074 1.00 69.50  ? 509 ALA   A CA  1 
ATOM   3652 C  C   . ALA   A 1 509 ? 99.868  90.967  125.350 1.00 69.50  ? 509 ALA   A C   1 
ATOM   3653 O  O   . ALA   A 1 509 ? 100.553 91.521  126.215 1.00 69.50  ? 509 ALA   A O   1 
ATOM   3654 C  CB  . ALA   A 1 509 ? 97.540  91.025  126.204 1.00 69.50  ? 509 ALA   A CB  1 
ATOM   3655 N  N   . VAL   A 1 510 ? 100.308 89.920  124.656 1.00 63.14  ? 510 VAL   A N   1 
ATOM   3656 C  CA  . VAL   A 1 510 ? 101.592 89.301  124.967 1.00 63.14  ? 510 VAL   A CA  1 
ATOM   3657 C  C   . VAL   A 1 510 ? 102.488 89.268  123.737 1.00 63.14  ? 510 VAL   A C   1 
ATOM   3658 O  O   . VAL   A 1 510 ? 103.644 89.702  123.788 1.00 63.14  ? 510 VAL   A O   1 
ATOM   3659 C  CB  . VAL   A 1 510 ? 101.397 87.884  125.535 1.00 63.14  ? 510 VAL   A CB  1 
ATOM   3660 C  CG1 . VAL   A 1 510 ? 102.733 87.169  125.651 1.00 63.14  ? 510 VAL   A CG1 1 
ATOM   3661 C  CG2 . VAL   A 1 510 ? 100.703 87.943  126.886 1.00 63.14  ? 510 VAL   A CG2 1 
ATOM   3662 N  N   . ILE   A 1 511 ? 101.964 88.749  122.626 1.00 63.29  ? 511 ILE   A N   1 
ATOM   3663 C  CA  . ILE   A 1 511 ? 102.808 88.465  121.469 1.00 63.29  ? 511 ILE   A CA  1 
ATOM   3664 C  C   . ILE   A 1 511 ? 103.315 89.751  120.826 1.00 63.29  ? 511 ILE   A C   1 
ATOM   3665 O  O   . ILE   A 1 511 ? 104.502 89.870  120.505 1.00 63.29  ? 511 ILE   A O   1 
ATOM   3666 C  CB  . ILE   A 1 511 ? 102.049 87.585  120.461 1.00 63.29  ? 511 ILE   A CB  1 
ATOM   3667 C  CG1 . ILE   A 1 511 ? 101.798 86.198  121.055 1.00 63.29  ? 511 ILE   A CG1 1 
ATOM   3668 C  CG2 . ILE   A 1 511 ? 102.827 87.467  119.164 1.00 63.29  ? 511 ILE   A CG2 1 
ATOM   3669 C  CD1 . ILE   A 1 511 ? 101.094 85.251  120.115 1.00 63.29  ? 511 ILE   A CD1 1 
ATOM   3670 N  N   . THR   A 1 512 ? 102.441 90.731  120.630 1.00 62.69  ? 512 THR   A N   1 
ATOM   3671 C  CA  . THR   A 1 512 ? 102.841 91.935  119.906 1.00 62.69  ? 512 THR   A CA  1 
ATOM   3672 C  C   . THR   A 1 512 ? 103.692 92.887  120.750 1.00 62.69  ? 512 THR   A C   1 
ATOM   3673 O  O   . THR   A 1 512 ? 104.726 93.365  120.260 1.00 62.69  ? 512 THR   A O   1 
ATOM   3674 C  CB  . THR   A 1 512 ? 101.608 92.660  119.357 1.00 62.69  ? 512 THR   A CB  1 
ATOM   3675 O  OG1 . THR   A 1 512 ? 101.025 91.881  118.306 1.00 62.69  ? 512 THR   A OG1 1 
ATOM   3676 C  CG2 . THR   A 1 512 ? 101.991 94.023  118.808 1.00 62.69  ? 512 THR   A CG2 1 
ATOM   3677 N  N   . PRO   A 1 513 ? 103.310 93.207  121.998 1.00 63.74  ? 513 PRO   A N   1 
ATOM   3678 C  CA  . PRO   A 1 513 ? 104.140 94.144  122.775 1.00 63.74  ? 513 PRO   A CA  1 
ATOM   3679 C  C   . PRO   A 1 513 ? 105.579 93.694  122.949 1.00 63.74  ? 513 PRO   A C   1 
ATOM   3680 O  O   . PRO   A 1 513 ? 106.491 94.530  122.907 1.00 63.74  ? 513 PRO   A O   1 
ATOM   3681 C  CB  . PRO   A 1 513 ? 103.406 94.220  124.120 1.00 63.74  ? 513 PRO   A CB  1 
ATOM   3682 C  CG  . PRO   A 1 513 ? 102.003 93.929  123.785 1.00 63.74  ? 513 PRO   A CG  1 
ATOM   3683 C  CD  . PRO   A 1 513 ? 102.075 92.868  122.730 1.00 63.74  ? 513 PRO   A CD  1 
ATOM   3684 N  N   . VAL   A 1 514 ? 105.813 92.396  123.147 1.00 59.97  ? 514 VAL   A N   1 
ATOM   3685 C  CA  . VAL   A 1 514 ? 107.179 91.911  123.321 1.00 59.97  ? 514 VAL   A CA  1 
ATOM   3686 C  C   . VAL   A 1 514 ? 107.981 92.100  122.040 1.00 59.97  ? 514 VAL   A C   1 
ATOM   3687 O  O   . VAL   A 1 514 ? 109.107 92.610  122.066 1.00 59.97  ? 514 VAL   A O   1 
ATOM   3688 C  CB  . VAL   A 1 514 ? 107.171 90.440  123.775 1.00 59.97  ? 514 VAL   A CB  1 
ATOM   3689 C  CG1 . VAL   A 1 514 ? 108.579 89.872  123.754 1.00 59.97  ? 514 VAL   A CG1 1 
ATOM   3690 C  CG2 . VAL   A 1 514 ? 106.567 90.321  125.163 1.00 59.97  ? 514 VAL   A CG2 1 
ATOM   3691 N  N   . LEU   A 1 515 ? 107.414 91.699  120.899 1.00 61.88  ? 515 LEU   A N   1 
ATOM   3692 C  CA  . LEU   A 1 515 ? 108.119 91.843  119.630 1.00 61.88  ? 515 LEU   A CA  1 
ATOM   3693 C  C   . LEU   A 1 515 ? 108.269 93.295  119.201 1.00 61.88  ? 515 LEU   A C   1 
ATOM   3694 O  O   . LEU   A 1 515 ? 109.090 93.583  118.324 1.00 61.88  ? 515 LEU   A O   1 
ATOM   3695 C  CB  . LEU   A 1 515 ? 107.419 91.043  118.530 1.00 61.88  ? 515 LEU   A CB  1 
ATOM   3696 C  CG  . LEU   A 1 515 ? 107.766 89.555  118.415 1.00 61.88  ? 515 LEU   A CG  1 
ATOM   3697 C  CD1 . LEU   A 1 515 ? 107.211 88.728  119.561 1.00 61.88  ? 515 LEU   A CD1 1 
ATOM   3698 C  CD2 . LEU   A 1 515 ? 107.283 89.013  117.080 1.00 61.88  ? 515 LEU   A CD2 1 
ATOM   3699 N  N   . CYS   A 1 516 ? 107.500 94.215  119.783 1.00 62.54  ? 516 CYS   A N   1 
ATOM   3700 C  CA  . CYS   A 1 516 ? 107.742 95.628  119.510 1.00 62.54  ? 516 CYS   A CA  1 
ATOM   3701 C  C   . CYS   A 1 516 ? 108.848 96.182  120.402 1.00 62.54  ? 516 CYS   A C   1 
ATOM   3702 O  O   . CYS   A 1 516 ? 109.817 96.780  119.911 1.00 62.54  ? 516 CYS   A O   1 
ATOM   3703 C  CB  . CYS   A 1 516 ? 106.453 96.430  119.696 1.00 62.54  ? 516 CYS   A CB  1 
ATOM   3704 S  SG  . CYS   A 1 516 ? 105.152 96.050  118.503 1.00 62.54  ? 516 CYS   A SG  1 
ATOM   3705 N  N   . VAL   A 1 517 ? 108.721 95.980  121.716 1.00 62.36  ? 517 VAL   A N   1 
ATOM   3706 C  CA  . VAL   A 1 517 ? 109.663 96.581  122.652 1.00 62.36  ? 517 VAL   A CA  1 
ATOM   3707 C  C   . VAL   A 1 517 ? 111.053 95.976  122.499 1.00 62.36  ? 517 VAL   A C   1 
ATOM   3708 O  O   . VAL   A 1 517 ? 112.056 96.690  122.617 1.00 62.36  ? 517 VAL   A O   1 
ATOM   3709 C  CB  . VAL   A 1 517 ? 109.136 96.468  124.097 1.00 62.36  ? 517 VAL   A CB  1 
ATOM   3710 C  CG1 . VAL   A 1 517 ? 109.188 95.033  124.597 1.00 62.36  ? 517 VAL   A CG1 1 
ATOM   3711 C  CG2 . VAL   A 1 517 ? 109.920 97.386  125.019 1.00 62.36  ? 517 VAL   A CG2 1 
ATOM   3712 N  N   . GLY   A 1 518 ? 111.152 94.674  122.220 1.00 66.28  ? 518 GLY   A N   1 
ATOM   3713 C  CA  . GLY   A 1 518 ? 112.463 94.073  122.048 1.00 66.28  ? 518 GLY   A CA  1 
ATOM   3714 C  C   . GLY   A 1 518 ? 113.195 94.629  120.843 1.00 66.28  ? 518 GLY   A C   1 
ATOM   3715 O  O   . GLY   A 1 518 ? 114.379 94.963  120.920 1.00 66.28  ? 518 GLY   A O   1 
ATOM   3716 N  N   . CYS   A 1 519 ? 112.493 94.743  119.713 1.00 71.27  ? 519 CYS   A N   1 
ATOM   3717 C  CA  . CYS   A 1 519 ? 113.109 95.310  118.518 1.00 71.27  ? 519 CYS   A CA  1 
ATOM   3718 C  C   . CYS   A 1 519 ? 113.514 96.760  118.741 1.00 71.27  ? 519 CYS   A C   1 
ATOM   3719 O  O   . CYS   A 1 519 ? 114.599 97.177  118.323 1.00 71.27  ? 519 CYS   A O   1 
ATOM   3720 C  CB  . CYS   A 1 519 ? 112.162 95.191  117.325 1.00 71.27  ? 519 CYS   A CB  1 
ATOM   3721 S  SG  . CYS   A 1 519 ? 111.839 93.492  116.805 1.00 71.27  ? 519 CYS   A SG  1 
ATOM   3722 N  N   . PHE   A 1 520 ? 112.661 97.543  119.407 1.00 68.89  ? 520 PHE   A N   1 
ATOM   3723 C  CA  . PHE   A 1 520 ? 112.996 98.944  119.652 1.00 68.89  ? 520 PHE   A CA  1 
ATOM   3724 C  C   . PHE   A 1 520 ? 114.225 99.070  120.551 1.00 68.89  ? 520 PHE   A C   1 
ATOM   3725 O  O   . PHE   A 1 520 ? 115.140 99.859  120.272 1.00 68.89  ? 520 PHE   A O   1 
ATOM   3726 C  CB  . PHE   A 1 520 ? 111.784 99.659  120.252 1.00 68.89  ? 520 PHE   A CB  1 
ATOM   3727 C  CG  . PHE   A 1 520 ? 111.981 101.131 120.459 1.00 68.89  ? 520 PHE   A CG  1 
ATOM   3728 C  CD1 . PHE   A 1 520 ? 112.434 101.626 121.669 1.00 68.89  ? 520 PHE   A CD1 1 
ATOM   3729 C  CD2 . PHE   A 1 520 ? 111.721 102.022 119.433 1.00 68.89  ? 520 PHE   A CD2 1 
ATOM   3730 C  CE1 . PHE   A 1 520 ? 112.606 102.984 121.854 1.00 68.89  ? 520 PHE   A CE1 1 
ATOM   3731 C  CE2 . PHE   A 1 520 ? 111.900 103.379 119.610 1.00 68.89  ? 520 PHE   A CE2 1 
ATOM   3732 C  CZ  . PHE   A 1 520 ? 112.344 103.860 120.822 1.00 68.89  ? 520 PHE   A CZ  1 
ATOM   3733 N  N   . ILE   A 1 521 ? 114.276 98.277  121.625 1.00 69.64  ? 521 ILE   A N   1 
ATOM   3734 C  CA  . ILE   A 1 521 ? 115.413 98.330  122.541 1.00 69.64  ? 521 ILE   A CA  1 
ATOM   3735 C  C   . ILE   A 1 521 ? 116.689 97.879  121.842 1.00 69.64  ? 521 ILE   A C   1 
ATOM   3736 O  O   . ILE   A 1 521 ? 117.751 98.493  122.004 1.00 69.64  ? 521 ILE   A O   1 
ATOM   3737 C  CB  . ILE   A 1 521 ? 115.127 97.493  123.801 1.00 69.64  ? 521 ILE   A CB  1 
ATOM   3738 C  CG1 . ILE   A 1 521 ? 114.079 98.185  124.674 1.00 69.64  ? 521 ILE   A CG1 1 
ATOM   3739 C  CG2 . ILE   A 1 521 ? 116.404 97.256  124.592 1.00 69.64  ? 521 ILE   A CG2 1 
ATOM   3740 C  CD1 . ILE   A 1 521 ? 114.507 99.545  125.179 1.00 69.64  ? 521 ILE   A CD1 1 
ATOM   3741 N  N   . PHE   A 1 522 ? 116.614 96.800  121.058 1.00 71.67  ? 522 PHE   A N   1 
ATOM   3742 C  CA  . PHE   A 1 522 ? 117.798 96.332  120.346 1.00 71.67  ? 522 PHE   A CA  1 
ATOM   3743 C  C   . PHE   A 1 522 ? 118.269 97.343  119.309 1.00 71.67  ? 522 PHE   A C   1 
ATOM   3744 O  O   . PHE   A 1 522 ? 119.478 97.493  119.100 1.00 71.67  ? 522 PHE   A O   1 
ATOM   3745 C  CB  . PHE   A 1 522 ? 117.525 94.976  119.697 1.00 71.67  ? 522 PHE   A CB  1 
ATOM   3746 C  CG  . PHE   A 1 522 ? 117.819 93.809  120.596 1.00 71.67  ? 522 PHE   A CG  1 
ATOM   3747 C  CD1 . PHE   A 1 522 ? 119.120 93.371  120.775 1.00 71.67  ? 522 PHE   A CD1 1 
ATOM   3748 C  CD2 . PHE   A 1 522 ? 116.801 93.154  121.266 1.00 71.67  ? 522 PHE   A CD2 1 
ATOM   3749 C  CE1 . PHE   A 1 522 ? 119.399 92.300  121.604 1.00 71.67  ? 522 PHE   A CE1 1 
ATOM   3750 C  CE2 . PHE   A 1 522 ? 117.074 92.082  122.096 1.00 71.67  ? 522 PHE   A CE2 1 
ATOM   3751 C  CZ  . PHE   A 1 522 ? 118.375 91.655  122.265 1.00 71.67  ? 522 PHE   A CZ  1 
ATOM   3752 N  N   . SER   A 1 523 ? 117.340 98.041  118.651 1.00 71.92  ? 523 SER   A N   1 
ATOM   3753 C  CA  . SER   A 1 523 ? 117.734 99.101  117.730 1.00 71.92  ? 523 SER   A CA  1 
ATOM   3754 C  C   . SER   A 1 523 ? 118.447 100.230 118.461 1.00 71.92  ? 523 SER   A C   1 
ATOM   3755 O  O   . SER   A 1 523 ? 119.431 100.779 117.953 1.00 71.92  ? 523 SER   A O   1 
ATOM   3756 C  CB  . SER   A 1 523 ? 116.511 99.632  116.984 1.00 71.92  ? 523 SER   A CB  1 
ATOM   3757 O  OG  . SER   A 1 523 ? 116.870 100.686 116.108 1.00 71.92  ? 523 SER   A OG  1 
ATOM   3758 N  N   . LEU   A 1 524 ? 117.963 100.598 119.650 1.00 73.93  ? 524 LEU   A N   1 
ATOM   3759 C  CA  . LEU   A 1 524 ? 118.637 101.648 120.413 1.00 73.93  ? 524 LEU   A CA  1 
ATOM   3760 C  C   . LEU   A 1 524 ? 120.033 101.214 120.844 1.00 73.93  ? 524 LEU   A C   1 
ATOM   3761 O  O   . LEU   A 1 524 ? 121.004 101.963 120.692 1.00 73.93  ? 524 LEU   A O   1 
ATOM   3762 C  CB  . LEU   A 1 524 ? 117.816 102.038 121.640 1.00 73.93  ? 524 LEU   A CB  1 
ATOM   3763 C  CG  . LEU   A 1 524 ? 116.460 102.708 121.458 1.00 73.93  ? 524 LEU   A CG  1 
ATOM   3764 C  CD1 . LEU   A 1 524 ? 115.806 102.861 122.820 1.00 73.93  ? 524 LEU   A CD1 1 
ATOM   3765 C  CD2 . LEU   A 1 524 ? 116.612 104.049 120.764 1.00 73.93  ? 524 LEU   A CD2 1 
ATOM   3766 N  N   . VAL   A 1 525 ? 120.150 100.005 121.398 1.00 76.46  ? 525 VAL   A N   1 
ATOM   3767 C  CA  . VAL   A 1 525 ? 121.426 99.564  121.955 1.00 76.46  ? 525 VAL   A CA  1 
ATOM   3768 C  C   . VAL   A 1 525 ? 122.449 99.333  120.850 1.00 76.46  ? 525 VAL   A C   1 
ATOM   3769 O  O   . VAL   A 1 525 ? 123.592 99.796  120.939 1.00 76.46  ? 525 VAL   A O   1 
ATOM   3770 C  CB  . VAL   A 1 525 ? 121.226 98.305  122.817 1.00 76.46  ? 525 VAL   A CB  1 
ATOM   3771 C  CG1 . VAL   A 1 525 ? 122.563 97.794  123.326 1.00 76.46  ? 525 VAL   A CG1 1 
ATOM   3772 C  CG2 . VAL   A 1 525 ? 120.293 98.602  123.980 1.00 76.46  ? 525 VAL   A CG2 1 
ATOM   3773 N  N   . LYS   A 1 526 ? 122.061 98.623  119.794 1.00 77.60  ? 526 LYS   A N   1 
ATOM   3774 C  CA  . LYS   A 1 526 ? 122.947 98.336  118.668 1.00 77.60  ? 526 LYS   A CA  1 
ATOM   3775 C  C   . LYS   A 1 526 ? 122.610 99.313  117.548 1.00 77.60  ? 526 LYS   A C   1 
ATOM   3776 O  O   . LYS   A 1 526 ? 121.577 99.184  116.888 1.00 77.60  ? 526 LYS   A O   1 
ATOM   3777 C  CB  . LYS   A 1 526 ? 122.803 96.885  118.216 1.00 77.60  ? 526 LYS   A CB  1 
ATOM   3778 C  CG  . LYS   A 1 526 ? 123.026 95.799  119.291 1.00 77.60  ? 526 LYS   A CG  1 
ATOM   3779 C  CD  . LYS   A 1 526 ? 124.187 96.010  120.289 1.00 77.60  ? 526 LYS   A CD  1 
ATOM   3780 C  CE  . LYS   A 1 526 ? 125.488 96.530  119.665 1.00 77.60  ? 526 LYS   A CE  1 
ATOM   3781 N  NZ  . LYS   A 1 526 ? 126.500 96.875  120.701 1.00 77.60  ? 526 LYS   A NZ  1 
ATOM   3782 N  N   . TYR   A 1 527 ? 123.488 100.287 117.332 1.00 75.64  ? 527 TYR   A N   1 
ATOM   3783 C  CA  . TYR   A 1 527 ? 123.256 101.359 116.376 1.00 75.64  ? 527 TYR   A CA  1 
ATOM   3784 C  C   . TYR   A 1 527 ? 124.237 101.265 115.216 1.00 75.64  ? 527 TYR   A C   1 
ATOM   3785 O  O   . TYR   A 1 527 ? 125.435 101.042 115.417 1.00 75.64  ? 527 TYR   A O   1 
ATOM   3786 C  CB  . TYR   A 1 527 ? 123.379 102.729 117.049 1.00 75.64  ? 527 TYR   A CB  1 
ATOM   3787 C  CG  . TYR   A 1 527 ? 122.676 103.840 116.304 1.00 75.64  ? 527 TYR   A CG  1 
ATOM   3788 C  CD1 . TYR   A 1 527 ? 123.266 104.446 115.204 1.00 75.64  ? 527 TYR   A CD1 1 
ATOM   3789 C  CD2 . TYR   A 1 527 ? 121.421 104.281 116.699 1.00 75.64  ? 527 TYR   A CD2 1 
ATOM   3790 C  CE1 . TYR   A 1 527 ? 122.629 105.460 114.518 1.00 75.64  ? 527 TYR   A CE1 1 
ATOM   3791 C  CE2 . TYR   A 1 527 ? 120.775 105.295 116.020 1.00 75.64  ? 527 TYR   A CE2 1 
ATOM   3792 C  CZ  . TYR   A 1 527 ? 121.384 105.881 114.931 1.00 75.64  ? 527 TYR   A CZ  1 
ATOM   3793 O  OH  . TYR   A 1 527 ? 120.747 106.891 114.249 1.00 75.64  ? 527 TYR   A OH  1 
ATOM   3794 N  N   . VAL   A 1 528 ? 123.716 101.435 114.005 1.00 76.19  ? 528 VAL   A N   1 
ATOM   3795 C  CA  . VAL   A 1 528 ? 124.526 101.495 112.791 1.00 76.19  ? 528 VAL   A CA  1 
ATOM   3796 C  C   . VAL   A 1 528 ? 124.067 102.699 111.976 1.00 76.19  ? 528 VAL   A C   1 
ATOM   3797 O  O   . VAL   A 1 528 ? 122.867 102.829 111.696 1.00 76.19  ? 528 VAL   A O   1 
ATOM   3798 C  CB  . VAL   A 1 528 ? 124.418 100.197 111.974 1.00 76.19  ? 528 VAL   A CB  1 
ATOM   3799 C  CG1 . VAL   A 1 528 ? 125.185 100.328 110.667 1.00 76.19  ? 528 VAL   A CG1 1 
ATOM   3800 C  CG2 . VAL   A 1 528 ? 124.930 99.013  112.778 1.00 76.19  ? 528 VAL   A CG2 1 
ATOM   3801 N  N   . PRO   A 1 529 ? 124.966 103.600 111.587 1.00 74.16  ? 529 PRO   A N   1 
ATOM   3802 C  CA  . PRO   A 1 529 ? 124.546 104.762 110.797 1.00 74.16  ? 529 PRO   A CA  1 
ATOM   3803 C  C   . PRO   A 1 529 ? 124.017 104.353 109.432 1.00 74.16  ? 529 PRO   A C   1 
ATOM   3804 O  O   . PRO   A 1 529 ? 124.478 103.384 108.823 1.00 74.16  ? 529 PRO   A O   1 
ATOM   3805 C  CB  . PRO   A 1 529 ? 125.831 105.588 110.673 1.00 74.16  ? 529 PRO   A CB  1 
ATOM   3806 C  CG  . PRO   A 1 529 ? 126.928 104.587 110.815 1.00 74.16  ? 529 PRO   A CG  1 
ATOM   3807 C  CD  . PRO   A 1 529 ? 126.421 103.583 111.813 1.00 74.16  ? 529 PRO   A CD  1 
ATOM   3808 N  N   . LEU   A 1 530 ? 123.035 105.113 108.954 1.00 70.29  ? 530 LEU   A N   1 
ATOM   3809 C  CA  . LEU   A 1 530 ? 122.415 104.817 107.669 1.00 70.29  ? 530 LEU   A CA  1 
ATOM   3810 C  C   . LEU   A 1 530 ? 123.360 105.182 106.531 1.00 70.29  ? 530 LEU   A C   1 
ATOM   3811 O  O   . LEU   A 1 530 ? 123.956 106.263 106.526 1.00 70.29  ? 530 LEU   A O   1 
ATOM   3812 C  CB  . LEU   A 1 530 ? 121.095 105.575 107.534 1.00 70.29  ? 530 LEU   A CB  1 
ATOM   3813 C  CG  . LEU   A 1 530 ? 120.502 105.705 106.130 1.00 70.29  ? 530 LEU   A CG  1 
ATOM   3814 C  CD1 . LEU   A 1 530 ? 120.111 104.342 105.586 1.00 70.29  ? 530 LEU   A CD1 1 
ATOM   3815 C  CD2 . LEU   A 1 530 ? 119.304 106.638 106.144 1.00 70.29  ? 530 LEU   A CD2 1 
ATOM   3816 N  N   . THR   A 1 531 ? 123.496 104.276 105.564 1.00 78.04  ? 531 THR   A N   1 
ATOM   3817 C  CA  . THR   A 1 531 ? 124.380 104.467 104.424 1.00 78.04  ? 531 THR   A CA  1 
ATOM   3818 C  C   . THR   A 1 531 ? 123.609 104.250 103.131 1.00 78.04  ? 531 THR   A C   1 
ATOM   3819 O  O   . THR   A 1 531 ? 122.650 103.473 103.092 1.00 78.04  ? 531 THR   A O   1 
ATOM   3820 C  CB  . THR   A 1 531 ? 125.583 103.515 104.480 1.00 78.04  ? 531 THR   A CB  1 
ATOM   3821 O  OG1 . THR   A 1 531 ? 126.372 103.667 103.293 1.00 78.04  ? 531 THR   A OG1 1 
ATOM   3822 C  CG2 . THR   A 1 531 ? 125.120 102.073 104.597 1.00 78.04  ? 531 THR   A CG2 1 
ATOM   3823 N  N   . TYR   A 1 532 ? 124.030 104.944 102.077 1.00 74.07  ? 532 TYR   A N   1 
ATOM   3824 C  CA  . TYR   A 1 532 ? 123.399 104.832 100.769 1.00 74.07  ? 532 TYR   A CA  1 
ATOM   3825 C  C   . TYR   A 1 532 ? 124.321 104.079 99.820  1.00 74.07  ? 532 TYR   A C   1 
ATOM   3826 O  O   . TYR   A 1 532 ? 125.458 104.501 99.586  1.00 74.07  ? 532 TYR   A O   1 
ATOM   3827 C  CB  . TYR   A 1 532 ? 123.073 106.219 100.210 1.00 74.07  ? 532 TYR   A CB  1 
ATOM   3828 C  CG  . TYR   A 1 532 ? 122.611 106.230 98.767  1.00 74.07  ? 532 TYR   A CG  1 
ATOM   3829 C  CD1 . TYR   A 1 532 ? 121.267 106.094 98.448  1.00 74.07  ? 532 TYR   A CD1 1 
ATOM   3830 C  CD2 . TYR   A 1 532 ? 123.517 106.394 97.725  1.00 74.07  ? 532 TYR   A CD2 1 
ATOM   3831 C  CE1 . TYR   A 1 532 ? 120.839 106.108 97.133  1.00 74.07  ? 532 TYR   A CE1 1 
ATOM   3832 C  CE2 . TYR   A 1 532 ? 123.098 106.408 96.408  1.00 74.07  ? 532 TYR   A CE2 1 
ATOM   3833 C  CZ  . TYR   A 1 532 ? 121.759 106.266 96.119  1.00 74.07  ? 532 TYR   A CZ  1 
ATOM   3834 O  OH  . TYR   A 1 532 ? 121.338 106.281 94.809  1.00 74.07  ? 532 TYR   A OH  1 
ATOM   3835 N  N   . ASN   A 1 533 ? 123.827 102.960 99.285  1.00 81.47  ? 533 ASN   A N   1 
ATOM   3836 C  CA  . ASN   A 1 533 ? 124.570 102.141 98.323  1.00 81.47  ? 533 ASN   A CA  1 
ATOM   3837 C  C   . ASN   A 1 533 ? 125.895 101.650 98.903  1.00 81.47  ? 533 ASN   A C   1 
ATOM   3838 O  O   . ASN   A 1 533 ? 126.846 101.370 98.168  1.00 81.47  ? 533 ASN   A O   1 
ATOM   3839 C  CB  . ASN   A 1 533 ? 124.799 102.899 97.012  1.00 81.47  ? 533 ASN   A CB  1 
ATOM   3840 C  CG  . ASN   A 1 533 ? 125.034 101.972 95.835  1.00 81.47  ? 533 ASN   A CG  1 
ATOM   3841 O  OD1 . ASN   A 1 533 ? 124.945 100.752 95.964  1.00 81.47  ? 533 ASN   A OD1 1 
ATOM   3842 N  ND2 . ASN   A 1 533 ? 125.339 102.550 94.680  1.00 81.47  ? 533 ASN   A ND2 1 
ATOM   3843 N  N   . LYS   A 1 534 ? 125.967 101.561 100.235 1.00 82.54  ? 534 LYS   A N   1 
ATOM   3844 C  CA  . LYS   A 1 534 ? 127.124 101.032 100.953 1.00 82.54  ? 534 LYS   A CA  1 
ATOM   3845 C  C   . LYS   A 1 534 ? 128.394 101.840 100.704 1.00 82.54  ? 534 LYS   A C   1 
ATOM   3846 O  O   . LYS   A 1 534 ? 129.482 101.430 101.121 1.00 82.54  ? 534 LYS   A O   1 
ATOM   3847 C  CB  . LYS   A 1 534 ? 127.364 99.562  100.587 1.00 82.54  ? 534 LYS   A CB  1 
ATOM   3848 C  CG  . LYS   A 1 534 ? 126.105 98.714  100.506 1.00 82.54  ? 534 LYS   A CG  1 
ATOM   3849 C  CD  . LYS   A 1 534 ? 126.437 97.277  100.140 1.00 82.54  ? 534 LYS   A CD  1 
ATOM   3850 C  CE  . LYS   A 1 534 ? 125.347 96.659  99.282  1.00 82.54  ? 534 LYS   A CE  1 
ATOM   3851 N  NZ  . LYS   A 1 534 ? 125.361 97.206  97.897  1.00 82.54  ? 534 LYS   A NZ  1 
ATOM   3852 N  N   . THR   A 1 535 ? 128.277 102.983 100.026 1.00 78.96  ? 535 THR   A N   1 
ATOM   3853 C  CA  . THR   A 1 535 ? 129.462 103.774 99.711  1.00 78.96  ? 535 THR   A CA  1 
ATOM   3854 C  C   . THR   A 1 535 ? 129.394 105.153 100.357 1.00 78.96  ? 535 THR   A C   1 
ATOM   3855 O  O   . THR   A 1 535 ? 130.327 105.574 101.051 1.00 78.96  ? 535 THR   A O   1 
ATOM   3856 C  CB  . THR   A 1 535 ? 129.622 103.899 98.196  1.00 78.96  ? 535 THR   A CB  1 
ATOM   3857 N  N   . TYR   A 1 536 ? 128.297 105.870 100.136 1.00 74.79  ? 536 TYR   A N   1 
ATOM   3858 C  CA  . TYR   A 1 536 ? 128.178 107.232 100.637 1.00 74.79  ? 536 TYR   A CA  1 
ATOM   3859 C  C   . TYR   A 1 536 ? 128.017 107.244 102.152 1.00 74.79  ? 536 TYR   A C   1 
ATOM   3860 O  O   . TYR   A 1 536 ? 127.358 106.377 102.732 1.00 74.79  ? 536 TYR   A O   1 
ATOM   3861 C  CB  . TYR   A 1 536 ? 126.991 107.934 99.979  1.00 74.79  ? 536 TYR   A CB  1 
ATOM   3862 C  CG  . TYR   A 1 536 ? 126.835 109.383 100.379 1.00 74.79  ? 536 TYR   A CG  1 
ATOM   3863 C  CD1 . TYR   A 1 536 ? 127.756 110.337 99.974  1.00 74.79  ? 536 TYR   A CD1 1 
ATOM   3864 C  CD2 . TYR   A 1 536 ? 125.767 109.794 101.164 1.00 74.79  ? 536 TYR   A CD2 1 
ATOM   3865 C  CE1 . TYR   A 1 536 ? 127.618 111.661 100.338 1.00 74.79  ? 536 TYR   A CE1 1 
ATOM   3866 C  CE2 . TYR   A 1 536 ? 125.621 111.115 101.533 1.00 74.79  ? 536 TYR   A CE2 1 
ATOM   3867 C  CZ  . TYR   A 1 536 ? 126.549 112.045 101.117 1.00 74.79  ? 536 TYR   A CZ  1 
ATOM   3868 O  OH  . TYR   A 1 536 ? 126.408 113.363 101.483 1.00 74.79  ? 536 TYR   A OH  1 
ATOM   3869 N  N   . VAL   A 1 537 ? 128.628 108.238 102.792 1.00 76.33  ? 537 VAL   A N   1 
ATOM   3870 C  CA  . VAL   A 1 537 ? 128.506 108.460 104.228 1.00 76.33  ? 537 VAL   A CA  1 
ATOM   3871 C  C   . VAL   A 1 537 ? 127.787 109.784 104.436 1.00 76.33  ? 537 VAL   A C   1 
ATOM   3872 O  O   . VAL   A 1 537 ? 128.268 110.833 103.992 1.00 76.33  ? 537 VAL   A O   1 
ATOM   3873 C  CB  . VAL   A 1 537 ? 129.878 108.466 104.925 1.00 76.33  ? 537 VAL   A CB  1 
ATOM   3874 C  CG1 . VAL   A 1 537 ? 129.703 108.525 106.434 1.00 76.33  ? 537 VAL   A CG1 1 
ATOM   3875 C  CG2 . VAL   A 1 537 ? 130.681 107.240 104.524 1.00 76.33  ? 537 VAL   A CG2 1 
ATOM   3876 N  N   . TYR   A 1 538 ? 126.647 109.735 105.108 1.00 73.78  ? 538 TYR   A N   1 
ATOM   3877 C  CA  . TYR   A 1 538 ? 125.824 110.922 105.253 1.00 73.78  ? 538 TYR   A CA  1 
ATOM   3878 C  C   . TYR   A 1 538 ? 126.424 111.889 106.271 1.00 73.78  ? 538 TYR   A C   1 
ATOM   3879 O  O   . TYR   A 1 538 ? 127.051 111.468 107.247 1.00 73.78  ? 538 TYR   A O   1 
ATOM   3880 C  CB  . TYR   A 1 538 ? 124.412 110.537 105.679 1.00 73.78  ? 538 TYR   A CB  1 
ATOM   3881 C  CG  . TYR   A 1 538 ? 123.549 110.063 104.535 1.00 73.78  ? 538 TYR   A CG  1 
ATOM   3882 C  CD1 . TYR   A 1 538 ? 123.595 108.743 104.109 1.00 73.78  ? 538 TYR   A CD1 1 
ATOM   3883 C  CD2 . TYR   A 1 538 ? 122.694 110.935 103.876 1.00 73.78  ? 538 TYR   A CD2 1 
ATOM   3884 C  CE1 . TYR   A 1 538 ? 122.812 108.305 103.063 1.00 73.78  ? 538 TYR   A CE1 1 
ATOM   3885 C  CE2 . TYR   A 1 538 ? 121.907 110.505 102.829 1.00 73.78  ? 538 TYR   A CE2 1 
ATOM   3886 C  CZ  . TYR   A 1 538 ? 121.970 109.189 102.428 1.00 73.78  ? 538 TYR   A CZ  1 
ATOM   3887 O  OH  . TYR   A 1 538 ? 121.189 108.754 101.385 1.00 73.78  ? 538 TYR   A OH  1 
ATOM   3888 N  N   . PRO   A 1 539 ? 126.252 113.192 106.058 1.00 76.37  ? 539 PRO   A N   1 
ATOM   3889 C  CA  . PRO   A 1 539 ? 126.666 114.167 107.070 1.00 76.37  ? 539 PRO   A CA  1 
ATOM   3890 C  C   . PRO   A 1 539 ? 125.845 114.019 108.341 1.00 76.37  ? 539 PRO   A C   1 
ATOM   3891 O  O   . PRO   A 1 539 ? 124.704 113.551 108.329 1.00 76.37  ? 539 PRO   A O   1 
ATOM   3892 C  CB  . PRO   A 1 539 ? 126.407 115.518 106.392 1.00 76.37  ? 539 PRO   A CB  1 
ATOM   3893 C  CG  . PRO   A 1 539 ? 126.411 115.215 104.930 1.00 76.37  ? 539 PRO   A CG  1 
ATOM   3894 C  CD  . PRO   A 1 539 ? 125.824 113.842 104.808 1.00 76.37  ? 539 PRO   A CD  1 
ATOM   3895 N  N   . ASN   A 1 540 ? 126.453 114.427 109.457 1.00 76.68  ? 540 ASN   A N   1 
ATOM   3896 C  CA  . ASN   A 1 540 ? 125.812 114.263 110.759 1.00 76.68  ? 540 ASN   A CA  1 
ATOM   3897 C  C   . ASN   A 1 540 ? 124.501 115.037 110.840 1.00 76.68  ? 540 ASN   A C   1 
ATOM   3898 O  O   . ASN   A 1 540 ? 123.525 114.556 111.430 1.00 76.68  ? 540 ASN   A O   1 
ATOM   3899 C  CB  . ASN   A 1 540 ? 126.768 114.701 111.867 1.00 76.68  ? 540 ASN   A CB  1 
ATOM   3900 C  CG  . ASN   A 1 540 ? 128.192 114.244 111.620 1.00 76.68  ? 540 ASN   A CG  1 
ATOM   3901 O  OD1 . ASN   A 1 540 ? 129.091 115.060 111.416 1.00 76.68  ? 540 ASN   A OD1 1 
ATOM   3902 N  ND2 . ASN   A 1 540 ? 128.404 112.934 111.632 1.00 76.68  ? 540 ASN   A ND2 1 
ATOM   3903 N  N   . TRP   A 1 541 ? 124.458 116.241 110.263 1.00 74.67  ? 541 TRP   A N   1 
ATOM   3904 C  CA  . TRP   A 1 541 ? 123.225 117.019 110.293 1.00 74.67  ? 541 TRP   A CA  1 
ATOM   3905 C  C   . TRP   A 1 541 ? 122.117 116.345 109.490 1.00 74.67  ? 541 TRP   A C   1 
ATOM   3906 O  O   . TRP   A 1 541 ? 120.938 116.490 109.825 1.00 74.67  ? 541 TRP   A O   1 
ATOM   3907 C  CB  . TRP   A 1 541 ? 123.480 118.441 109.785 1.00 74.67  ? 541 TRP   A CB  1 
ATOM   3908 C  CG  . TRP   A 1 541 ? 123.757 118.536 108.317 1.00 74.67  ? 541 TRP   A CG  1 
ATOM   3909 C  CD1 . TRP   A 1 541 ? 124.964 118.386 107.700 1.00 74.67  ? 541 TRP   A CD1 1 
ATOM   3910 C  CD2 . TRP   A 1 541 ? 122.809 118.817 107.282 1.00 74.67  ? 541 TRP   A CD2 1 
ATOM   3911 N  NE1 . TRP   A 1 541 ? 124.825 118.548 106.343 1.00 74.67  ? 541 TRP   A NE1 1 
ATOM   3912 C  CE2 . TRP   A 1 541 ? 123.511 118.814 106.061 1.00 74.67  ? 541 TRP   A CE2 1 
ATOM   3913 C  CE3 . TRP   A 1 541 ? 121.434 119.067 107.268 1.00 74.67  ? 541 TRP   A CE3 1 
ATOM   3914 C  CZ2 . TRP   A 1 541 ? 122.885 119.052 104.840 1.00 74.67  ? 541 TRP   A CZ2 1 
ATOM   3915 C  CZ3 . TRP   A 1 541 ? 120.815 119.302 106.056 1.00 74.67  ? 541 TRP   A CZ3 1 
ATOM   3916 C  CH2 . TRP   A 1 541 ? 121.540 119.294 104.859 1.00 74.67  ? 541 TRP   A CH2 1 
ATOM   3917 N  N   . ALA   A 1 542 ? 122.470 115.593 108.445 1.00 69.98  ? 542 ALA   A N   1 
ATOM   3918 C  CA  . ALA   A 1 542 ? 121.459 114.836 107.712 1.00 69.98  ? 542 ALA   A CA  1 
ATOM   3919 C  C   . ALA   A 1 542 ? 120.837 113.753 108.587 1.00 69.98  ? 542 ALA   A C   1 
ATOM   3920 O  O   . ALA   A 1 542 ? 119.614 113.556 108.577 1.00 69.98  ? 542 ALA   A O   1 
ATOM   3921 C  CB  . ALA   A 1 542 ? 122.072 114.225 106.453 1.00 69.98  ? 542 ALA   A CB  1 
ATOM   3922 N  N   . ILE   A 1 543 ? 121.666 113.039 109.351 1.00 68.75  ? 543 ILE   A N   1 
ATOM   3923 C  CA  . ILE   A 1 543 ? 121.148 112.024 110.262 1.00 68.75  ? 543 ILE   A CA  1 
ATOM   3924 C  C   . ILE   A 1 543 ? 120.302 112.673 111.349 1.00 68.75  ? 543 ILE   A C   1 
ATOM   3925 O  O   . ILE   A 1 543 ? 119.274 112.126 111.765 1.00 68.75  ? 543 ILE   A O   1 
ATOM   3926 C  CB  . ILE   A 1 543 ? 122.303 111.196 110.853 1.00 68.75  ? 543 ILE   A CB  1 
ATOM   3927 C  CG1 . ILE   A 1 543 ? 123.062 110.466 109.742 1.00 68.75  ? 543 ILE   A CG1 1 
ATOM   3928 C  CG2 . ILE   A 1 543 ? 121.784 110.201 111.877 1.00 68.75  ? 543 ILE   A CG2 1 
ATOM   3929 C  CD1 . ILE   A 1 543 ? 122.168 109.823 108.703 1.00 68.75  ? 543 ILE   A CD1 1 
ATOM   3930 N  N   . GLY   A 1 544 ? 120.718 113.849 111.824 1.00 67.53  ? 544 GLY   A N   1 
ATOM   3931 C  CA  . GLY   A 1 544 ? 119.895 114.580 112.773 1.00 67.53  ? 544 GLY   A CA  1 
ATOM   3932 C  C   . GLY   A 1 544 ? 118.546 114.963 112.195 1.00 67.53  ? 544 GLY   A C   1 
ATOM   3933 O  O   . GLY   A 1 544 ? 117.520 114.872 112.872 1.00 67.53  ? 544 GLY   A O   1 
ATOM   3934 N  N   . LEU   A 1 545 ? 118.530 115.391 110.931 1.00 65.76  ? 545 LEU   A N   1 
ATOM   3935 C  CA  . LEU   A 1 545 ? 117.276 115.734 110.268 1.00 65.76  ? 545 LEU   A CA  1 
ATOM   3936 C  C   . LEU   A 1 545 ? 116.367 114.517 110.146 1.00 65.76  ? 545 LEU   A C   1 
ATOM   3937 O  O   . LEU   A 1 545 ? 115.159 114.602 110.391 1.00 65.76  ? 545 LEU   A O   1 
ATOM   3938 C  CB  . LEU   A 1 545 ? 117.563 116.331 108.891 1.00 65.76  ? 545 LEU   A CB  1 
ATOM   3939 C  CG  . LEU   A 1 545 ? 116.351 116.567 107.989 1.00 65.76  ? 545 LEU   A CG  1 
ATOM   3940 C  CD1 . LEU   A 1 545 ? 115.471 117.673 108.549 1.00 65.76  ? 545 LEU   A CD1 1 
ATOM   3941 C  CD2 . LEU   A 1 545 ? 116.794 116.890 106.570 1.00 65.76  ? 545 LEU   A CD2 1 
ATOM   3942 N  N   . GLY   A 1 546 ? 116.934 113.371 109.767 1.00 64.39  ? 546 GLY   A N   1 
ATOM   3943 C  CA  . GLY   A 1 546 ? 116.130 112.159 109.671 1.00 64.39  ? 546 GLY   A CA  1 
ATOM   3944 C  C   . GLY   A 1 546 ? 115.586 111.711 111.015 1.00 64.39  ? 546 GLY   A C   1 
ATOM   3945 O  O   . GLY   A 1 546 ? 114.426 111.293 111.127 1.00 64.39  ? 546 GLY   A O   1 
ATOM   3946 N  N   . TRP   A 1 547 ? 116.416 111.790 112.057 1.00 63.21  ? 547 TRP   A N   1 
ATOM   3947 C  CA  . TRP   A 1 547 ? 115.954 111.427 113.390 1.00 63.21  ? 547 TRP   A CA  1 
ATOM   3948 C  C   . TRP   A 1 547 ? 114.872 112.382 113.871 1.00 63.21  ? 547 TRP   A C   1 
ATOM   3949 O  O   . TRP   A 1 547 ? 113.936 111.965 114.557 1.00 63.21  ? 547 TRP   A O   1 
ATOM   3950 C  CB  . TRP   A 1 547 ? 117.129 111.394 114.364 1.00 63.21  ? 547 TRP   A CB  1 
ATOM   3951 C  CG  . TRP   A 1 547 ? 117.620 110.007 114.627 1.00 63.21  ? 547 TRP   A CG  1 
ATOM   3952 C  CD1 . TRP   A 1 547 ? 118.814 109.474 114.241 1.00 63.21  ? 547 TRP   A CD1 1 
ATOM   3953 C  CD2 . TRP   A 1 547 ? 116.922 108.967 115.322 1.00 63.21  ? 547 TRP   A CD2 1 
ATOM   3954 N  NE1 . TRP   A 1 547 ? 118.905 108.168 114.658 1.00 63.21  ? 547 TRP   A NE1 1 
ATOM   3955 C  CE2 . TRP   A 1 547 ? 117.756 107.833 115.324 1.00 63.21  ? 547 TRP   A CE2 1 
ATOM   3956 C  CE3 . TRP   A 1 547 ? 115.673 108.887 115.947 1.00 63.21  ? 547 TRP   A CE3 1 
ATOM   3957 C  CZ2 . TRP   A 1 547 ? 117.384 106.634 115.926 1.00 63.21  ? 547 TRP   A CZ2 1 
ATOM   3958 C  CZ3 . TRP   A 1 547 ? 115.305 107.695 116.543 1.00 63.21  ? 547 TRP   A CZ3 1 
ATOM   3959 C  CH2 . TRP   A 1 547 ? 116.157 106.585 116.528 1.00 63.21  ? 547 TRP   A CH2 1 
ATOM   3960 N  N   . SER   A 1 548 ? 114.977 113.664 113.516 1.00 64.56  ? 548 SER   A N   1 
ATOM   3961 C  CA  . SER   A 1 548 ? 113.905 114.601 113.832 1.00 64.56  ? 548 SER   A CA  1 
ATOM   3962 C  C   . SER   A 1 548 ? 112.636 114.262 113.060 1.00 64.56  ? 548 SER   A C   1 
ATOM   3963 O  O   . SER   A 1 548 ? 111.527 114.407 113.585 1.00 64.56  ? 548 SER   A O   1 
ATOM   3964 C  CB  . SER   A 1 548 ? 114.350 116.032 113.536 1.00 64.56  ? 548 SER   A CB  1 
ATOM   3965 O  OG  . SER   A 1 548 ? 113.470 116.968 114.132 1.00 64.56  ? 548 SER   A OG  1 
ATOM   3966 N  N   . LEU   A 1 549 ? 112.782 113.810 111.813 1.00 64.43  ? 549 LEU   A N   1 
ATOM   3967 C  CA  . LEU   A 1 549 ? 111.622 113.399 111.026 1.00 64.43  ? 549 LEU   A CA  1 
ATOM   3968 C  C   . LEU   A 1 549 ? 110.889 112.247 111.701 1.00 64.43  ? 549 LEU   A C   1 
ATOM   3969 O  O   . LEU   A 1 549 ? 109.655 112.232 111.768 1.00 64.43  ? 549 LEU   A O   1 
ATOM   3970 C  CB  . LEU   A 1 549 ? 112.060 113.000 109.616 1.00 64.43  ? 549 LEU   A CB  1 
ATOM   3971 C  CG  . LEU   A 1 549 ? 111.860 113.997 108.473 1.00 64.43  ? 549 LEU   A CG  1 
ATOM   3972 C  CD1 . LEU   A 1 549 ? 112.350 113.401 107.165 1.00 64.43  ? 549 LEU   A CD1 1 
ATOM   3973 C  CD2 . LEU   A 1 549 ? 110.404 114.411 108.362 1.00 64.43  ? 549 LEU   A CD2 1 
ATOM   3974 N  N   . ALA   A 1 550 ? 111.641 111.266 112.203 1.00 65.13  ? 550 ALA   A N   1 
ATOM   3975 C  CA  . ALA   A 1 550 ? 111.012 110.147 112.907 1.00 65.13  ? 550 ALA   A CA  1 
ATOM   3976 C  C   . ALA   A 1 550 ? 110.443 110.581 114.257 1.00 65.13  ? 550 ALA   A C   1 
ATOM   3977 O  O   . ALA   A 1 550 ? 109.344 110.160 114.644 1.00 65.13  ? 550 ALA   A O   1 
ATOM   3978 C  CB  . ALA   A 1 550 ? 112.013 109.008 113.085 1.00 65.13  ? 550 ALA   A CB  1 
ATOM   3979 N  N   . LEU   A 1 551 ? 111.171 111.429 114.986 1.00 67.20  ? 551 LEU   A N   1 
ATOM   3980 C  CA  . LEU   A 1 551 ? 110.754 111.851 116.316 1.00 67.20  ? 551 LEU   A CA  1 
ATOM   3981 C  C   . LEU   A 1 551 ? 109.529 112.753 116.278 1.00 67.20  ? 551 LEU   A C   1 
ATOM   3982 O  O   . LEU   A 1 551 ? 108.764 112.769 117.245 1.00 67.20  ? 551 LEU   A O   1 
ATOM   3983 C  CB  . LEU   A 1 551 ? 111.922 112.553 117.021 1.00 67.20  ? 551 LEU   A CB  1 
ATOM   3984 C  CG  . LEU   A 1 551 ? 111.989 112.678 118.550 1.00 67.20  ? 551 LEU   A CG  1 
ATOM   3985 C  CD1 . LEU   A 1 551 ? 113.409 113.018 118.969 1.00 67.20  ? 551 LEU   A CD1 1 
ATOM   3986 C  CD2 . LEU   A 1 551 ? 111.036 113.726 119.105 1.00 67.20  ? 551 LEU   A CD2 1 
ATOM   3987 N  N   . SER   A 1 552 ? 109.310 113.477 115.180 1.00 68.63  ? 552 SER   A N   1 
ATOM   3988 C  CA  . SER   A 1 552 ? 108.092 114.270 115.056 1.00 68.63  ? 552 SER   A CA  1 
ATOM   3989 C  C   . SER   A 1 552 ? 106.857 113.383 115.129 1.00 68.63  ? 552 SER   A C   1 
ATOM   3990 O  O   . SER   A 1 552 ? 105.859 113.743 115.763 1.00 68.63  ? 552 SER   A O   1 
ATOM   3991 C  CB  . SER   A 1 552 ? 108.110 115.058 113.748 1.00 68.63  ? 552 SER   A CB  1 
ATOM   3992 O  OG  . SER   A 1 552 ? 108.568 114.253 112.677 1.00 68.63  ? 552 SER   A OG  1 
ATOM   3993 N  N   . SER   A 1 553 ? 106.906 112.216 114.483 1.00 68.57  ? 553 SER   A N   1 
ATOM   3994 C  CA  . SER   A 1 553 ? 105.805 111.266 114.587 1.00 68.57  ? 553 SER   A CA  1 
ATOM   3995 C  C   . SER   A 1 553 ? 105.807 110.557 115.937 1.00 68.57  ? 553 SER   A C   1 
ATOM   3996 O  O   . SER   A 1 553 ? 104.741 110.310 116.512 1.00 68.57  ? 553 SER   A O   1 
ATOM   3997 C  CB  . SER   A 1 553 ? 105.882 110.248 113.451 1.00 68.57  ? 553 SER   A CB  1 
ATOM   3998 O  OG  . SER   A 1 553 ? 104.817 109.320 113.539 1.00 68.57  ? 553 SER   A OG  1 
ATOM   3999 N  N   . MET   A 1 554 ? 106.992 110.217 116.454 1.00 68.13  ? 554 MET   A N   1 
ATOM   4000 C  CA  . MET   A 1 554 ? 107.059 109.481 117.716 1.00 68.13  ? 554 MET   A CA  1 
ATOM   4001 C  C   . MET   A 1 554 ? 106.475 110.283 118.874 1.00 68.13  ? 554 MET   A C   1 
ATOM   4002 O  O   . MET   A 1 554 ? 105.755 109.735 119.716 1.00 68.13  ? 554 MET   A O   1 
ATOM   4003 C  CB  . MET   A 1 554 ? 108.502 109.092 118.034 1.00 68.13  ? 554 MET   A CB  1 
ATOM   4004 C  CG  . MET   A 1 554 ? 109.102 108.044 117.123 1.00 68.13  ? 554 MET   A CG  1 
ATOM   4005 S  SD  . MET   A 1 554 ? 110.417 107.145 117.964 1.00 68.13  ? 554 MET   A SD  1 
ATOM   4006 C  CE  . MET   A 1 554 ? 111.846 108.117 117.497 1.00 68.13  ? 554 MET   A CE  1 
ATOM   4007 N  N   . LEU   A 1 555 ? 106.770 111.581 118.932 1.00 73.38  ? 555 LEU   A N   1 
ATOM   4008 C  CA  . LEU   A 1 555 ? 106.466 112.414 120.090 1.00 73.38  ? 555 LEU   A CA  1 
ATOM   4009 C  C   . LEU   A 1 555 ? 104.991 112.795 120.183 1.00 73.38  ? 555 LEU   A C   1 
ATOM   4010 O  O   . LEU   A 1 555 ? 104.597 113.452 121.154 1.00 73.38  ? 555 LEU   A O   1 
ATOM   4011 C  CB  . LEU   A 1 555 ? 107.354 113.663 120.044 1.00 73.38  ? 555 LEU   A CB  1 
ATOM   4012 C  CG  . LEU   A 1 555 ? 107.306 114.736 121.132 1.00 73.38  ? 555 LEU   A CG  1 
ATOM   4013 C  CD1 . LEU   A 1 555 ? 108.018 114.257 122.386 1.00 73.38  ? 555 LEU   A CD1 1 
ATOM   4014 C  CD2 . LEU   A 1 555 ? 107.921 116.030 120.626 1.00 73.38  ? 555 LEU   A CD2 1 
ATOM   4015 N  N   . CYS   A 1 556 ? 104.165 112.386 119.219 1.00 75.66  ? 556 CYS   A N   1 
ATOM   4016 C  CA  . CYS   A 1 556 ? 102.752 112.753 119.247 1.00 75.66  ? 556 CYS   A CA  1 
ATOM   4017 C  C   . CYS   A 1 556 ? 102.048 112.181 120.473 1.00 75.66  ? 556 CYS   A C   1 
ATOM   4018 O  O   . CYS   A 1 556 ? 101.198 112.849 121.074 1.00 75.66  ? 556 CYS   A O   1 
ATOM   4019 C  CB  . CYS   A 1 556 ? 102.064 112.280 117.967 1.00 75.66  ? 556 CYS   A CB  1 
ATOM   4020 S  SG  . CYS   A 1 556 ? 102.650 113.088 116.463 1.00 75.66  ? 556 CYS   A SG  1 
ATOM   4021 N  N   . VAL   A 1 557 ? 102.383 110.953 120.858 1.00 77.55  ? 557 VAL   A N   1 
ATOM   4022 C  CA  . VAL   A 1 557 ? 101.705 110.265 121.956 1.00 77.55  ? 557 VAL   A CA  1 
ATOM   4023 C  C   . VAL   A 1 557 ? 102.052 110.907 123.300 1.00 77.55  ? 557 VAL   A C   1 
ATOM   4024 O  O   . VAL   A 1 557 ? 101.132 111.312 124.029 1.00 77.55  ? 557 VAL   A O   1 
ATOM   4025 C  CB  . VAL   A 1 557 ? 102.028 108.761 121.948 1.00 77.55  ? 557 VAL   A CB  1 
ATOM   4026 C  CG1 . VAL   A 1 557 ? 101.337 108.060 123.102 1.00 77.55  ? 557 VAL   A CG1 1 
ATOM   4027 C  CG2 . VAL   A 1 557 ? 101.636 108.137 120.618 1.00 77.55  ? 557 VAL   A CG2 1 
ATOM   4028 N  N   . PRO   A 1 558 ? 103.330 111.022 123.690 1.00 77.66  ? 558 PRO   A N   1 
ATOM   4029 C  CA  . PRO   A 1 558 ? 103.617 111.637 124.996 1.00 77.66  ? 558 PRO   A CA  1 
ATOM   4030 C  C   . PRO   A 1 558 ? 103.130 113.069 125.105 1.00 77.66  ? 558 PRO   A C   1 
ATOM   4031 O  O   . PRO   A 1 558 ? 102.729 113.495 126.195 1.00 77.66  ? 558 PRO   A O   1 
ATOM   4032 C  CB  . PRO   A 1 558 ? 105.147 111.550 125.103 1.00 77.66  ? 558 PRO   A CB  1 
ATOM   4033 C  CG  . PRO   A 1 558 ? 105.553 110.533 124.095 1.00 77.66  ? 558 PRO   A CG  1 
ATOM   4034 C  CD  . PRO   A 1 558 ? 104.580 110.690 122.983 1.00 77.66  ? 558 PRO   A CD  1 
ATOM   4035 N  N   . LEU   A 1 559 ? 103.144 113.823 124.004 1.00 83.17  ? 559 LEU   A N   1 
ATOM   4036 C  CA  . LEU   A 1 559 ? 102.661 115.199 124.042 1.00 83.17  ? 559 LEU   A CA  1 
ATOM   4037 C  C   . LEU   A 1 559 ? 101.180 115.254 124.396 1.00 83.17  ? 559 LEU   A C   1 
ATOM   4038 O  O   . LEU   A 1 559 ? 100.773 116.013 125.282 1.00 83.17  ? 559 LEU   A O   1 
ATOM   4039 C  CB  . LEU   A 1 559 ? 102.918 115.884 122.700 1.00 83.17  ? 559 LEU   A CB  1 
ATOM   4040 C  CG  . LEU   A 1 559 ? 104.319 116.454 122.486 1.00 83.17  ? 559 LEU   A CG  1 
ATOM   4041 C  CD1 . LEU   A 1 559 ? 104.430 117.073 121.106 1.00 83.17  ? 559 LEU   A CD1 1 
ATOM   4042 C  CD2 . LEU   A 1 559 ? 104.649 117.473 123.562 1.00 83.17  ? 559 LEU   A CD2 1 
ATOM   4043 N  N   . VAL   A 1 560 ? 100.355 114.454 123.717 1.00 84.65  ? 560 VAL   A N   1 
ATOM   4044 C  CA  . VAL   A 1 560 ? 98.933  114.477 124.036 1.00 84.65  ? 560 VAL   A CA  1 
ATOM   4045 C  C   . VAL   A 1 560 ? 98.696  113.932 125.438 1.00 84.65  ? 560 VAL   A C   1 
ATOM   4046 O  O   . VAL   A 1 560 ? 97.806  114.413 126.149 1.00 84.65  ? 560 VAL   A O   1 
ATOM   4047 C  CB  . VAL   A 1 560 ? 98.107  113.722 122.974 1.00 84.65  ? 560 VAL   A CB  1 
ATOM   4048 C  CG1 . VAL   A 1 560 ? 98.351  114.312 121.592 1.00 84.65  ? 560 VAL   A CG1 1 
ATOM   4049 C  CG2 . VAL   A 1 560 ? 98.407  112.240 122.988 1.00 84.65  ? 560 VAL   A CG2 1 
ATOM   4050 N  N   . ILE   A 1 561 ? 99.489  112.947 125.874 1.00 86.34  ? 561 ILE   A N   1 
ATOM   4051 C  CA  . ILE   A 1 561 ? 99.325  112.429 127.231 1.00 86.34  ? 561 ILE   A CA  1 
ATOM   4052 C  C   . ILE   A 1 561 ? 99.577  113.526 128.258 1.00 86.34  ? 561 ILE   A C   1 
ATOM   4053 O  O   . ILE   A 1 561 ? 98.789  113.715 129.192 1.00 86.34  ? 561 ILE   A O   1 
ATOM   4054 C  CB  . ILE   A 1 561 ? 100.240 111.215 127.471 1.00 86.34  ? 561 ILE   A CB  1 
ATOM   4055 C  CG1 . ILE   A 1 561 ? 99.860  110.060 126.546 1.00 86.34  ? 561 ILE   A CG1 1 
ATOM   4056 C  CG2 . ILE   A 1 561 ? 100.165 110.772 128.923 1.00 86.34  ? 561 ILE   A CG2 1 
ATOM   4057 C  CD1 . ILE   A 1 561 ? 100.868 108.937 126.544 1.00 86.34  ? 561 ILE   A CD1 1 
ATOM   4058 N  N   . VAL   A 1 562 ? 100.671 114.275 128.098 1.00 91.67  ? 562 VAL   A N   1 
ATOM   4059 C  CA  . VAL   A 1 562 ? 100.982 115.307 129.084 1.00 91.67  ? 562 VAL   A CA  1 
ATOM   4060 C  C   . VAL   A 1 562 ? 99.986  116.460 129.000 1.00 91.67  ? 562 VAL   A C   1 
ATOM   4061 O  O   . VAL   A 1 562 ? 99.656  117.073 130.023 1.00 91.67  ? 562 VAL   A O   1 
ATOM   4062 C  CB  . VAL   A 1 562 ? 102.440 115.794 128.948 1.00 91.67  ? 562 VAL   A CB  1 
ATOM   4063 C  CG1 . VAL   A 1 562 ? 103.408 114.633 129.133 1.00 91.67  ? 562 VAL   A CG1 1 
ATOM   4064 C  CG2 . VAL   A 1 562 ? 102.676 116.485 127.620 1.00 91.67  ? 562 VAL   A CG2 1 
ATOM   4065 N  N   . ILE   A 1 563 ? 99.484  116.776 127.802 1.00 93.31  ? 563 ILE   A N   1 
ATOM   4066 C  CA  . ILE   A 1 563 ? 98.480  117.833 127.684 1.00 93.31  ? 563 ILE   A CA  1 
ATOM   4067 C  C   . ILE   A 1 563 ? 97.198  117.436 128.406 1.00 93.31  ? 563 ILE   A C   1 
ATOM   4068 O  O   . ILE   A 1 563 ? 96.623  118.226 129.164 1.00 93.31  ? 563 ILE   A O   1 
ATOM   4069 C  CB  . ILE   A 1 563 ? 98.216  118.173 126.207 1.00 93.31  ? 563 ILE   A CB  1 
ATOM   4070 C  CG1 . ILE   A 1 563 ? 99.481  118.729 125.555 1.00 93.31  ? 563 ILE   A CG1 1 
ATOM   4071 C  CG2 . ILE   A 1 563 ? 97.073  119.167 126.083 1.00 93.31  ? 563 ILE   A CG2 1 
ATOM   4072 C  CD1 . ILE   A 1 563 ? 99.387  118.844 124.058 1.00 93.31  ? 563 ILE   A CD1 1 
ATOM   4073 N  N   . ARG   A 1 564 ? 96.729  116.204 128.186 1.00 96.11  ? 564 ARG   A N   1 
ATOM   4074 C  CA  . ARG   A 1 564 ? 95.520  115.757 128.870 1.00 96.11  ? 564 ARG   A CA  1 
ATOM   4075 C  C   . ARG   A 1 564 ? 95.742  115.622 130.371 1.00 96.11  ? 564 ARG   A C   1 
ATOM   4076 O  O   . ARG   A 1 564 ? 94.807  115.829 131.153 1.00 96.11  ? 564 ARG   A O   1 
ATOM   4077 C  CB  . ARG   A 1 564 ? 95.029  114.436 128.277 1.00 96.11  ? 564 ARG   A CB  1 
ATOM   4078 C  CG  . ARG   A 1 564 ? 94.795  114.484 126.776 1.00 96.11  ? 564 ARG   A CG  1 
ATOM   4079 C  CD  . ARG   A 1 564 ? 94.094  113.233 126.275 1.00 96.11  ? 564 ARG   A CD  1 
ATOM   4080 N  NE  . ARG   A 1 564 ? 93.131  113.532 125.222 1.00 96.11  ? 564 ARG   A NE  1 
ATOM   4081 C  CZ  . ARG   A 1 564 ? 93.448  113.731 123.949 1.00 96.11  ? 564 ARG   A CZ  1 
ATOM   4082 N  NH1 . ARG   A 1 564 ? 94.702  113.672 123.532 1.00 96.11  ? 564 ARG   A NH1 1 
ATOM   4083 N  NH2 . ARG   A 1 564 ? 92.483  113.996 123.073 1.00 96.11  ? 564 ARG   A NH2 1 
ATOM   4084 N  N   . LEU   A 1 565 ? 96.961  115.277 130.793 1.00 101.47 ? 565 LEU   A N   1 
ATOM   4085 C  CA  . LEU   A 1 565 ? 97.261  115.229 132.220 1.00 101.47 ? 565 LEU   A CA  1 
ATOM   4086 C  C   . LEU   A 1 565 ? 97.221  116.619 132.839 1.00 101.47 ? 565 LEU   A C   1 
ATOM   4087 O  O   . LEU   A 1 565 ? 96.752  116.787 133.971 1.00 101.47 ? 565 LEU   A O   1 
ATOM   4088 C  CB  . LEU   A 1 565 ? 98.624  114.577 132.448 1.00 101.47 ? 565 LEU   A CB  1 
ATOM   4089 C  CG  . LEU   A 1 565 ? 98.647  113.048 132.422 1.00 101.47 ? 565 LEU   A CG  1 
ATOM   4090 C  CD1 . LEU   A 1 565 ? 100.077 112.531 132.434 1.00 101.47 ? 565 LEU   A CD1 1 
ATOM   4091 C  CD2 . LEU   A 1 565 ? 97.859  112.483 133.592 1.00 101.47 ? 565 LEU   A CD2 1 
ATOM   4092 N  N   . CYS   A 1 566 ? 97.717  117.627 132.116 1.00 104.98 ? 566 CYS   A N   1 
ATOM   4093 C  CA  . CYS   A 1 566 ? 97.683  118.992 132.632 1.00 104.98 ? 566 CYS   A CA  1 
ATOM   4094 C  C   . CYS   A 1 566 ? 96.251  119.471 132.832 1.00 104.98 ? 566 CYS   A C   1 
ATOM   4095 O  O   . CYS   A 1 566 ? 95.933  120.092 133.854 1.00 104.98 ? 566 CYS   A O   1 
ATOM   4096 C  CB  . CYS   A 1 566 ? 98.436  119.928 131.686 1.00 104.98 ? 566 CYS   A CB  1 
ATOM   4097 S  SG  . CYS   A 1 566 ? 98.731  121.584 132.348 1.00 104.98 ? 566 CYS   A SG  1 
ATOM   4098 N  N   . GLN   A 1 567 ? 95.373  119.185 131.876 1.00 104.36 ? 567 GLN   A N   1 
ATOM   4099 C  CA  . GLN   A 1 567 ? 93.972  119.577 131.975 1.00 104.36 ? 567 GLN   A CA  1 
ATOM   4100 C  C   . GLN   A 1 567 ? 93.108  118.764 131.017 1.00 104.36 ? 567 GLN   A C   1 
ATOM   4101 O  O   . GLN   A 1 567 ? 93.594  118.254 130.008 1.00 104.36 ? 567 GLN   A O   1 
ATOM   4102 C  CB  . GLN   A 1 567 ? 93.808  121.072 131.692 1.00 104.36 ? 567 GLN   A CB  1 
ATOM   4103 C  CG  . GLN   A 1 567 ? 92.502  121.662 132.202 1.00 104.36 ? 567 GLN   A CG  1 
ATOM   4104 C  CD  . GLN   A 1 567 ? 92.521  121.926 133.696 1.00 104.36 ? 567 GLN   A CD  1 
ATOM   4105 O  OE1 . GLN   A 1 567 ? 93.545  121.754 134.357 1.00 104.36 ? 567 GLN   A OE1 1 
ATOM   4106 N  NE2 . GLN   A 1 567 ? 91.382  122.345 134.236 1.00 104.36 ? 567 GLN   A NE2 1 
HETATM 4107 C  C1  . NAG   B 2 .   ? 126.601 106.536 68.966  1.00 111.30 ? 701 NAG   A C1  1 
HETATM 4108 C  C2  . NAG   B 2 .   ? 126.945 107.901 68.363  1.00 111.30 ? 701 NAG   A C2  1 
HETATM 4109 C  C3  . NAG   B 2 .   ? 126.004 108.226 67.204  1.00 111.30 ? 701 NAG   A C3  1 
HETATM 4110 C  C4  . NAG   B 2 .   ? 125.996 107.090 66.190  1.00 111.30 ? 701 NAG   A C4  1 
HETATM 4111 C  C5  . NAG   B 2 .   ? 125.689 105.765 66.881  1.00 111.30 ? 701 NAG   A C5  1 
HETATM 4112 C  C6  . NAG   B 2 .   ? 125.784 104.577 65.952  1.00 111.30 ? 701 NAG   A C6  1 
HETATM 4113 C  C7  . NAG   B 2 .   ? 125.830 109.320 70.058  1.00 111.30 ? 701 NAG   A C7  1 
HETATM 4114 C  C8  . NAG   B 2 .   ? 126.025 110.433 71.043  1.00 111.30 ? 701 NAG   A C8  1 
HETATM 4115 N  N2  . NAG   B 2 .   ? 126.918 108.956 69.366  1.00 111.30 ? 701 NAG   A N2  1 
HETATM 4116 O  O3  . NAG   B 2 .   ? 126.422 109.434 66.580  1.00 111.30 ? 701 NAG   A O3  1 
HETATM 4117 O  O4  . NAG   B 2 .   ? 125.012 107.337 65.192  1.00 111.30 ? 701 NAG   A O4  1 
HETATM 4118 O  O5  . NAG   B 2 .   ? 126.629 105.536 67.941  1.00 111.30 ? 701 NAG   A O5  1 
HETATM 4119 O  O6  . NAG   B 2 .   ? 127.091 104.018 65.957  1.00 111.30 ? 701 NAG   A O6  1 
HETATM 4120 O  O7  . NAG   B 2 .   ? 124.739 108.777 69.902  1.00 111.30 ? 701 NAG   A O7  1 
HETATM 4121 C  C1  . NAG   C 2 .   ? 132.138 88.196  72.412  1.00 150.20 ? 702 NAG   A C1  1 
HETATM 4122 C  C2  . NAG   C 2 .   ? 131.373 86.853  72.496  1.00 150.20 ? 702 NAG   A C2  1 
HETATM 4123 C  C3  . NAG   C 2 .   ? 129.857 87.071  72.568  1.00 150.20 ? 702 NAG   A C3  1 
HETATM 4124 C  C4  . NAG   C 2 .   ? 129.462 88.428  72.004  1.00 150.20 ? 702 NAG   A C4  1 
HETATM 4125 C  C5  . NAG   C 2 .   ? 130.336 88.748  70.801  1.00 150.20 ? 702 NAG   A C5  1 
HETATM 4126 C  C6  . NAG   C 2 .   ? 129.907 90.001  70.074  1.00 150.20 ? 702 NAG   A C6  1 
HETATM 4127 C  C7  . NAG   C 2 .   ? 132.409 84.841  71.534  1.00 150.20 ? 702 NAG   A C7  1 
HETATM 4128 C  C8  . NAG   C 2 .   ? 132.826 84.499  72.933  1.00 150.20 ? 702 NAG   A C8  1 
HETATM 4129 N  N2  . NAG   C 2 .   ? 131.717 85.976  71.387  1.00 150.20 ? 702 NAG   A N2  1 
HETATM 4130 O  O3  . NAG   C 2 .   ? 129.427 86.965  73.921  1.00 150.20 ? 702 NAG   A O3  1 
HETATM 4131 O  O4  . NAG   C 2 .   ? 128.097 88.411  71.602  1.00 150.20 ? 702 NAG   A O4  1 
HETATM 4132 O  O5  . NAG   C 2 .   ? 131.687 88.963  71.234  1.00 150.20 ? 702 NAG   A O5  1 
HETATM 4133 O  O6  . NAG   C 2 .   ? 128.496 90.169  70.119  1.00 150.20 ? 702 NAG   A O6  1 
HETATM 4134 O  O7  . NAG   C 2 .   ? 132.685 84.121  70.579  1.00 150.20 ? 702 NAG   A O7  1 
HETATM 4135 C  C1  . NAG   D 2 .   ? 139.756 100.597 85.447  1.00 132.49 ? 703 NAG   A C1  1 
HETATM 4136 C  C2  . NAG   D 2 .   ? 139.781 102.115 85.687  1.00 132.49 ? 703 NAG   A C2  1 
HETATM 4137 C  C3  . NAG   D 2 .   ? 141.004 102.502 86.518  1.00 132.49 ? 703 NAG   A C3  1 
HETATM 4138 C  C4  . NAG   D 2 .   ? 141.078 101.658 87.784  1.00 132.49 ? 703 NAG   A C4  1 
HETATM 4139 C  C5  . NAG   D 2 .   ? 140.987 100.172 87.445  1.00 132.49 ? 703 NAG   A C5  1 
HETATM 4140 C  C6  . NAG   D 2 .   ? 140.953 99.283  88.666  1.00 132.49 ? 703 NAG   A C6  1 
HETATM 4141 C  C7  . NAG   D 2 .   ? 140.671 102.788 83.477  1.00 132.49 ? 703 NAG   A C7  1 
HETATM 4142 C  C8  . NAG   D 2 .   ? 140.433 103.645 82.270  1.00 132.49 ? 703 NAG   A C8  1 
HETATM 4143 N  N2  . NAG   D 2 .   ? 139.740 102.863 84.437  1.00 132.49 ? 703 NAG   A N2  1 
HETATM 4144 O  O3  . NAG   D 2 .   ? 140.929 103.882 86.857  1.00 132.49 ? 703 NAG   A O3  1 
HETATM 4145 O  O4  . NAG   D 2 .   ? 142.306 101.907 88.461  1.00 132.49 ? 703 NAG   A O4  1 
HETATM 4146 O  O5  . NAG   D 2 .   ? 139.785 99.912  86.705  1.00 132.49 ? 703 NAG   A O5  1 
HETATM 4147 O  O6  . NAG   D 2 .   ? 142.238 98.747  88.951  1.00 132.49 ? 703 NAG   A O6  1 
HETATM 4148 O  O7  . NAG   D 2 .   ? 141.660 102.066 83.573  1.00 132.49 ? 703 NAG   A O7  1 
HETATM 4149 CL CL  . CL    E 3 .   ? 103.799 92.133  102.447 1.00 73.16  ? 704 CL    A CL  1 
HETATM 4150 C  CAA . Y01   F 4 .   ? 107.302 120.407 116.490 1.00 84.23  ? 705 Y01   A CAA 1 
HETATM 4151 C  CBA . Y01   F 4 .   ? 108.101 119.274 115.867 1.00 84.23  ? 705 Y01   A CBA 1 
HETATM 4152 C  CAB . Y01   F 4 .   ? 109.174 118.797 116.830 1.00 84.23  ? 705 Y01   A CAB 1 
HETATM 4153 C  CAN . Y01   F 4 .   ? 107.228 118.109 115.407 1.00 84.23  ? 705 Y01   A CAN 1 
HETATM 4154 C  CAJ . Y01   F 4 .   ? 106.368 118.334 114.162 1.00 84.23  ? 705 Y01   A CAJ 1 
HETATM 4155 C  CAO . Y01   F 4 .   ? 104.950 118.829 114.451 1.00 84.23  ? 705 Y01   A CAO 1 
HETATM 4156 C  CBB . Y01   F 4 .   ? 103.869 117.743 114.627 1.00 84.23  ? 705 Y01   A CBB 1 
HETATM 4157 C  CAC . Y01   F 4 .   ? 104.413 116.371 114.234 1.00 84.23  ? 705 Y01   A CAC 1 
HETATM 4158 C  CBE . Y01   F 4 .   ? 103.277 117.771 116.050 1.00 84.23  ? 705 Y01   A CBE 1 
HETATM 4159 C  CAP . Y01   F 4 .   ? 104.170 118.544 117.044 1.00 84.23  ? 705 Y01   A CAP 1 
HETATM 4160 C  CAQ . Y01   F 4 .   ? 103.229 119.063 118.149 1.00 84.23  ? 705 Y01   A CAQ 1 
HETATM 4161 C  CBG . Y01   F 4 .   ? 101.866 118.439 117.817 1.00 84.23  ? 705 Y01   A CBG 1 
HETATM 4162 C  CBI . Y01   F 4 .   ? 101.867 118.359 116.278 1.00 84.23  ? 705 Y01   A CBI 1 
HETATM 4163 C  CAE . Y01   F 4 .   ? 101.727 119.754 115.645 1.00 84.23  ? 705 Y01   A CAE 1 
HETATM 4164 C  CAU . Y01   F 4 .   ? 100.678 117.473 115.885 1.00 84.23  ? 705 Y01   A CAU 1 
HETATM 4165 C  CAS . Y01   F 4 .   ? 99.359  118.003 116.447 1.00 84.23  ? 705 Y01   A CAS 1 
HETATM 4166 C  CBF . Y01   F 4 .   ? 99.379  118.216 117.966 1.00 84.23  ? 705 Y01   A CBF 1 
HETATM 4167 C  CBD . Y01   F 4 .   ? 100.593 119.043 118.417 1.00 84.23  ? 705 Y01   A CBD 1 
HETATM 4168 C  CAK . Y01   F 4 .   ? 100.680 119.057 119.941 1.00 84.23  ? 705 Y01   A CAK 1 
HETATM 4169 C  CAI . Y01   F 4 .   ? 99.347  119.192 120.609 1.00 84.23  ? 705 Y01   A CAI 1 
HETATM 4170 C  CAZ . Y01   F 4 .   ? 98.176  119.078 120.001 1.00 84.23  ? 705 Y01   A CAZ 1 
HETATM 4171 C  CAV . Y01   F 4 .   ? 96.888  119.224 120.776 1.00 84.23  ? 705 Y01   A CAV 1 
HETATM 4172 C  CBH . Y01   F 4 .   ? 98.039  118.786 118.514 1.00 84.23  ? 705 Y01   A CBH 1 
HETATM 4173 C  CAD . Y01   F 4 .   ? 97.640  120.090 117.798 1.00 84.23  ? 705 Y01   A CAD 1 
HETATM 4174 C  CAT . Y01   F 4 .   ? 96.934  117.737 118.322 1.00 84.23  ? 705 Y01   A CAT 1 
HETATM 4175 C  CAR . Y01   F 4 .   ? 96.595  117.020 119.630 1.00 84.23  ? 705 Y01   A CAR 1 
HETATM 4176 C  CBC . Y01   F 4 .   ? 96.015  117.989 120.638 1.00 84.23  ? 705 Y01   A CBC 1 
HETATM 4177 O  OAW . Y01   F 4 .   ? 94.693  118.413 120.183 1.00 84.23  ? 705 Y01   A OAW 1 
HETATM 4178 C  CAY . Y01   F 4 .   ? 93.737  118.549 121.113 1.00 84.23  ? 705 Y01   A CAY 1 
HETATM 4179 O  OAG . Y01   F 4 .   ? 93.543  117.753 121.992 1.00 84.23  ? 705 Y01   A OAG 1 
HETATM 4180 C  CAM . Y01   F 4 .   ? 92.957  119.814 120.907 1.00 84.23  ? 705 Y01   A CAM 1 
HETATM 4181 C  CAL . Y01   F 4 .   ? 92.428  120.409 122.200 1.00 84.23  ? 705 Y01   A CAL 1 
HETATM 4182 C  CAX . Y01   F 4 .   ? 91.320  119.608 122.820 1.00 84.23  ? 705 Y01   A CAX 1 
HETATM 4183 O  OAH . Y01   F 4 .   ? 90.411  119.125 122.178 1.00 84.23  ? 705 Y01   A OAH 1 
HETATM 4184 O  OAF . Y01   F 4 .   ? 91.432  119.485 124.118 1.00 84.23  ? 705 Y01   A OAF 1 
HETATM 4185 C  CAA . Y01   G 4 .   ? 101.617 118.363 104.728 1.00 97.74  ? 706 Y01   A CAA 1 
HETATM 4186 C  CBA . Y01   G 4 .   ? 102.040 118.912 106.080 1.00 97.74  ? 706 Y01   A CBA 1 
HETATM 4187 C  CAB . Y01   G 4 .   ? 101.597 120.357 106.232 1.00 97.74  ? 706 Y01   A CAB 1 
HETATM 4188 C  CAN . Y01   G 4 .   ? 101.539 118.050 107.231 1.00 97.74  ? 706 Y01   A CAN 1 
HETATM 4189 C  CAJ . Y01   G 4 .   ? 102.074 118.422 108.609 1.00 97.74  ? 706 Y01   A CAJ 1 
HETATM 4190 C  CAO . Y01   G 4 .   ? 101.458 117.613 109.747 1.00 97.74  ? 706 Y01   A CAO 1 
HETATM 4191 C  CBB . Y01   G 4 .   ? 99.939  117.778 109.930 1.00 97.74  ? 706 Y01   A CBB 1 
HETATM 4192 C  CAC . Y01   G 4 .   ? 99.244  116.425 109.813 1.00 97.74  ? 706 Y01   A CAC 1 
HETATM 4193 C  CBE . Y01   G 4 .   ? 99.634  118.513 111.251 1.00 97.74  ? 706 Y01   A CBE 1 
HETATM 4194 C  CAP . Y01   G 4 .   ? 100.493 119.788 111.410 1.00 97.74  ? 706 Y01   A CAP 1 
HETATM 4195 C  CAQ . Y01   G 4 .   ? 99.637  120.814 112.168 1.00 97.74  ? 706 Y01   A CAQ 1 
HETATM 4196 C  CBG . Y01   G 4 .   ? 98.459  119.986 112.690 1.00 97.74  ? 706 Y01   A CBG 1 
HETATM 4197 C  CBI . Y01   G 4 .   ? 98.188  118.983 111.551 1.00 97.74  ? 706 Y01   A CBI 1 
HETATM 4198 C  CAE . Y01   G 4 .   ? 97.562  119.677 110.330 1.00 97.74  ? 706 Y01   A CAE 1 
HETATM 4199 C  CAU . Y01   G 4 .   ? 97.224  117.933 112.123 1.00 97.74  ? 706 Y01   A CAU 1 
HETATM 4200 C  CAS . Y01   G 4 .   ? 95.945  118.562 112.678 1.00 97.74  ? 706 Y01   A CAS 1 
HETATM 4201 C  CBF . Y01   G 4 .   ? 96.202  119.661 113.719 1.00 97.74  ? 706 Y01   A CBF 1 
HETATM 4202 C  CBD . Y01   G 4 .   ? 97.210  120.702 113.213 1.00 97.74  ? 706 Y01   A CBD 1 
HETATM 4203 C  CAK . Y01   G 4 .   ? 97.579  121.655 114.344 1.00 97.74  ? 706 Y01   A CAK 1 
HETATM 4204 C  CAI . Y01   G 4 .   ? 96.380  122.125 115.103 1.00 97.74  ? 706 Y01   A CAI 1 
HETATM 4205 C  CAZ . Y01   G 4 .   ? 95.189  121.545 115.082 1.00 97.74  ? 706 Y01   A CAZ 1 
HETATM 4206 C  CAV . Y01   G 4 .   ? 94.045  122.111 115.886 1.00 97.74  ? 706 Y01   A CAV 1 
HETATM 4207 C  CBH . Y01   G 4 .   ? 94.886  120.296 114.259 1.00 97.74  ? 706 Y01   A CBH 1 
HETATM 4208 C  CAD . Y01   G 4 .   ? 93.936  120.695 113.113 1.00 97.74  ? 706 Y01   A CAD 1 
HETATM 4209 C  CAT . Y01   G 4 .   ? 94.182  119.273 115.166 1.00 97.74  ? 706 Y01   A CAT 1 
HETATM 4210 C  CAR . Y01   G 4 .   ? 92.968  119.860 115.887 1.00 97.74  ? 706 Y01   A CAR 1 
HETATM 4211 C  CBC . Y01   G 4 .   ? 93.379  121.043 116.735 1.00 97.74  ? 706 Y01   A CBC 1 
HETATM 4212 O  OAW . Y01   G 4 .   ? 92.177  121.608 117.353 1.00 97.74  ? 706 Y01   A OAW 1 
HETATM 4213 C  CAY . Y01   G 4 .   ? 92.210  122.888 117.762 1.00 97.74  ? 706 Y01   A CAY 1 
HETATM 4214 O  OAG . Y01   G 4 .   ? 91.790  123.809 117.112 1.00 97.74  ? 706 Y01   A OAG 1 
HETATM 4215 C  CAM . Y01   G 4 .   ? 92.796  123.008 119.139 1.00 97.74  ? 706 Y01   A CAM 1 
HETATM 4216 C  CAL . Y01   G 4 .   ? 94.210  123.564 119.147 1.00 97.74  ? 706 Y01   A CAL 1 
HETATM 4217 C  CAX . Y01   G 4 .   ? 94.359  124.835 118.362 1.00 97.74  ? 706 Y01   A CAX 1 
HETATM 4218 O  OAH . Y01   G 4 .   ? 95.292  124.770 117.447 1.00 97.74  ? 706 Y01   A OAH 1 
HETATM 4219 O  OAF . Y01   G 4 .   ? 93.679  125.821 118.556 1.00 97.74  ? 706 Y01   A OAF 1 
HETATM 4220 NA NA  . NA    H 5 .   ? 96.717  99.879  96.155  1.00 20.00  ? 707 NA    A NA  1 
HETATM 4221 C  C01 . A1EBD I 6 .   ? 99.708  101.036 101.009 1.00 68.07  ? 708 A1EBD A C01 1 
HETATM 4222 C  C02 . A1EBD I 6 .   ? 99.776  102.205 101.987 1.00 68.07  ? 708 A1EBD A C02 1 
HETATM 4223 C  C04 . A1EBD I 6 .   ? 102.221 102.030 102.021 1.00 68.07  ? 708 A1EBD A C04 1 
HETATM 4224 C  C05 . A1EBD I 6 .   ? 102.154 100.859 101.044 1.00 68.07  ? 708 A1EBD A C05 1 
HETATM 4225 C  C06 . A1EBD I 6 .   ? 100.942 100.928 100.196 1.00 68.07  ? 708 A1EBD A C06 1 
HETATM 4226 N  N03 . A1EBD I 6 .   ? 100.990 102.145 102.831 1.00 68.07  ? 708 A1EBD A N03 1 
HETATM 4227 O  O08 . A1EBD I 6 .   ? 99.410  99.138  98.802  1.00 68.07  ? 708 A1EBD A O08 1 
HETATM 4228 O  O09 . A1EBD I 6 .   ? 101.470 99.636  97.827  1.00 68.07  ? 708 A1EBD A O09 1 
HETATM 4229 O  O10 . A1EBD I 6 .   ? 101.465 98.260  99.905  1.00 68.07  ? 708 A1EBD A O10 1 
HETATM 4230 S  S07 . A1EBD I 6 .   ? 100.840 99.428  99.183  1.00 68.07  ? 708 A1EBD A S07 1 
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