data_9JB0
# 
_entry.id   9JB0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JB0         pdb_00009jb0 10.2210/pdb9jb0/pdb 
WWPDB D_1300050441 ?            ?                   
EMDB  EMD-61303    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-26 ? 
2 'Structure model' 1 1 2025-04-02 ? 
3 'Structure model' 1 2 2025-04-09 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' citation        
5 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_last'               
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_citation_author.name'             
5 2 'Structure model' '_em_admin.last_update'             
6 3 'Structure model' '_citation.journal_volume'          
7 3 'Structure model' '_citation.title'                   
8 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JB0 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of the class II amyloid-beta 42 fibril containing a D-Asp at position 23' 
_pdbx_database_related.db_id          EMD-61303 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              sthsu@gate.sinica.edu.tw 
_pdbx_contact_author.name_first         Shang-Te 
_pdbx_contact_author.name_last          Hsu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7231-0185 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hsiao, L.C.' 1 0009-0001-1945-0744 
'Lee, C.H.'   2 0000-0002-7470-3249 
'Hsu, M.F.'   3 0000-0002-5473-5171 
'Hsu, S.T.'   4 0000-0002-7231-0185 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Mol.Biol. 
_citation.journal_id_ASTM           JMOBAK 
_citation.journal_id_CSD            0070 
_citation.journal_id_ISSN           1089-8638 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            437 
_citation.language                  ? 
_citation.page_first                169092 
_citation.page_last                 169092 
_citation.title                     
'Impacts of D-aspartate on the Aggregation Kinetics and Structural Polymorphism of Amyloid beta Peptide 1-42.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jmb.2025.169092 
_citation.pdbx_database_id_PubMed   40090459 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hsiao, L.C.'         1  ? 
primary 'Lee, C.H.'           2  ? 
primary 'Mazmanian, K.'       3  ? 
primary 'Yoshida, M.'         4  ? 
primary 'Ito, G.'             5  ? 
primary 'Murata, T.'          6  ? 
primary 'Utsunomiya-Tate, N.' 7  ? 
primary 'Haino, T.'           8  ? 
primary 'Tate, S.I.'          9  ? 
primary 'Hsu, S.D.'           10 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 syn 
_entity.pdbx_description           'Amyloid-beta precursor protein' 
_entity.formula_weight             4520.087 
_entity.pdbx_number_of_molecules   12 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;APP,ABPP,APPI,Alzheimer disease amyloid A4 protein homolog,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta (A4) precursor protein,Amyloid-beta A4 protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       'DAEFRHDSGYEVHHQKLVFFAE(DAS)VGSNKGAIIGLMVGGVVIA' 
_entity_poly.pdbx_seq_one_letter_code_can   DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 
_entity_poly.pdbx_strand_id                 CC,BB,DD,EE,FF,AA,A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1  ASP n 
1 2  ALA n 
1 3  GLU n 
1 4  PHE n 
1 5  ARG n 
1 6  HIS n 
1 7  ASP n 
1 8  SER n 
1 9  GLY n 
1 10 TYR n 
1 11 GLU n 
1 12 VAL n 
1 13 HIS n 
1 14 HIS n 
1 15 GLN n 
1 16 LYS n 
1 17 LEU n 
1 18 VAL n 
1 19 PHE n 
1 20 PHE n 
1 21 ALA n 
1 22 GLU n 
1 23 DAS n 
1 24 VAL n 
1 25 GLY n 
1 26 SER n 
1 27 ASN n 
1 28 LYS n 
1 29 GLY n 
1 30 ALA n 
1 31 ILE n 
1 32 ILE n 
1 33 GLY n 
1 34 LEU n 
1 35 MET n 
1 36 VAL n 
1 37 GLY n 
1 38 GLY n 
1 39 VAL n 
1 40 VAL n 
1 41 ILE n 
1 42 ALA n 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       42 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   human 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ? 'C4 H7 N O4'     133.103 
DAS 'D-peptide linking' . 'D-ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE         ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE        ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE     ? 'C9 H11 N O2'    165.189 
SER 'L-peptide linking' y SERINE            ? 'C3 H7 N O3'     105.093 
TYR 'L-peptide linking' y TYROSINE          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1  ASP 1  1  ?  ?   ?   CC . n 
A 1 2  ALA 2  2  ?  ?   ?   CC . n 
A 1 3  GLU 3  3  ?  ?   ?   CC . n 
A 1 4  PHE 4  4  ?  ?   ?   CC . n 
A 1 5  ARG 5  5  ?  ?   ?   CC . n 
A 1 6  HIS 6  6  ?  ?   ?   CC . n 
A 1 7  ASP 7  7  ?  ?   ?   CC . n 
A 1 8  SER 8  8  ?  ?   ?   CC . n 
A 1 9  GLY 9  9  9  GLY GLY CC . n 
A 1 10 TYR 10 10 10 TYR TYR CC . n 
A 1 11 GLU 11 11 11 GLU GLU CC . n 
A 1 12 VAL 12 12 12 VAL VAL CC . n 
A 1 13 HIS 13 13 13 HIS HIS CC . n 
A 1 14 HIS 14 14 14 HIS HIS CC . n 
A 1 15 GLN 15 15 15 GLN GLN CC . n 
A 1 16 LYS 16 16 16 LYS LYS CC . n 
A 1 17 LEU 17 17 17 LEU LEU CC . n 
A 1 18 VAL 18 18 18 VAL VAL CC . n 
A 1 19 PHE 19 19 19 PHE PHE CC . n 
A 1 20 PHE 20 20 20 PHE PHE CC . n 
A 1 21 ALA 21 21 21 ALA ALA CC . n 
A 1 22 GLU 22 22 22 GLU GLU CC . n 
A 1 23 DAS 23 23 23 DAS DAS CC . n 
A 1 24 VAL 24 24 24 VAL VAL CC . n 
A 1 25 GLY 25 25 25 GLY GLY CC . n 
A 1 26 SER 26 26 26 SER SER CC . n 
A 1 27 ASN 27 27 27 ASN ASN CC . n 
A 1 28 LYS 28 28 28 LYS LYS CC . n 
A 1 29 GLY 29 29 29 GLY GLY CC . n 
A 1 30 ALA 30 30 30 ALA ALA CC . n 
A 1 31 ILE 31 31 31 ILE ILE CC . n 
A 1 32 ILE 32 32 32 ILE ILE CC . n 
A 1 33 GLY 33 33 33 GLY GLY CC . n 
A 1 34 LEU 34 34 34 LEU LEU CC . n 
A 1 35 MET 35 35 35 MET MET CC . n 
A 1 36 VAL 36 36 36 VAL VAL CC . n 
A 1 37 GLY 37 37 37 GLY GLY CC . n 
A 1 38 GLY 38 38 38 GLY GLY CC . n 
A 1 39 VAL 39 39 39 VAL VAL CC . n 
A 1 40 VAL 40 40 40 VAL VAL CC . n 
A 1 41 ILE 41 41 41 ILE ILE CC . n 
A 1 42 ALA 42 42 42 ALA ALA CC . n 
B 1 1  ASP 1  1  ?  ?   ?   BB . n 
B 1 2  ALA 2  2  ?  ?   ?   BB . n 
B 1 3  GLU 3  3  ?  ?   ?   BB . n 
B 1 4  PHE 4  4  ?  ?   ?   BB . n 
B 1 5  ARG 5  5  ?  ?   ?   BB . n 
B 1 6  HIS 6  6  ?  ?   ?   BB . n 
B 1 7  ASP 7  7  ?  ?   ?   BB . n 
B 1 8  SER 8  8  ?  ?   ?   BB . n 
B 1 9  GLY 9  9  9  GLY GLY BB . n 
B 1 10 TYR 10 10 10 TYR TYR BB . n 
B 1 11 GLU 11 11 11 GLU GLU BB . n 
B 1 12 VAL 12 12 12 VAL VAL BB . n 
B 1 13 HIS 13 13 13 HIS HIS BB . n 
B 1 14 HIS 14 14 14 HIS HIS BB . n 
B 1 15 GLN 15 15 15 GLN GLN BB . n 
B 1 16 LYS 16 16 16 LYS LYS BB . n 
B 1 17 LEU 17 17 17 LEU LEU BB . n 
B 1 18 VAL 18 18 18 VAL VAL BB . n 
B 1 19 PHE 19 19 19 PHE PHE BB . n 
B 1 20 PHE 20 20 20 PHE PHE BB . n 
B 1 21 ALA 21 21 21 ALA ALA BB . n 
B 1 22 GLU 22 22 22 GLU GLU BB . n 
B 1 23 DAS 23 23 23 DAS DAS BB . n 
B 1 24 VAL 24 24 24 VAL VAL BB . n 
B 1 25 GLY 25 25 25 GLY GLY BB . n 
B 1 26 SER 26 26 26 SER SER BB . n 
B 1 27 ASN 27 27 27 ASN ASN BB . n 
B 1 28 LYS 28 28 28 LYS LYS BB . n 
B 1 29 GLY 29 29 29 GLY GLY BB . n 
B 1 30 ALA 30 30 30 ALA ALA BB . n 
B 1 31 ILE 31 31 31 ILE ILE BB . n 
B 1 32 ILE 32 32 32 ILE ILE BB . n 
B 1 33 GLY 33 33 33 GLY GLY BB . n 
B 1 34 LEU 34 34 34 LEU LEU BB . n 
B 1 35 MET 35 35 35 MET MET BB . n 
B 1 36 VAL 36 36 36 VAL VAL BB . n 
B 1 37 GLY 37 37 37 GLY GLY BB . n 
B 1 38 GLY 38 38 38 GLY GLY BB . n 
B 1 39 VAL 39 39 39 VAL VAL BB . n 
B 1 40 VAL 40 40 40 VAL VAL BB . n 
B 1 41 ILE 41 41 41 ILE ILE BB . n 
B 1 42 ALA 42 42 42 ALA ALA BB . n 
C 1 1  ASP 1  1  ?  ?   ?   DD . n 
C 1 2  ALA 2  2  ?  ?   ?   DD . n 
C 1 3  GLU 3  3  ?  ?   ?   DD . n 
C 1 4  PHE 4  4  ?  ?   ?   DD . n 
C 1 5  ARG 5  5  ?  ?   ?   DD . n 
C 1 6  HIS 6  6  ?  ?   ?   DD . n 
C 1 7  ASP 7  7  ?  ?   ?   DD . n 
C 1 8  SER 8  8  ?  ?   ?   DD . n 
C 1 9  GLY 9  9  9  GLY GLY DD . n 
C 1 10 TYR 10 10 10 TYR TYR DD . n 
C 1 11 GLU 11 11 11 GLU GLU DD . n 
C 1 12 VAL 12 12 12 VAL VAL DD . n 
C 1 13 HIS 13 13 13 HIS HIS DD . n 
C 1 14 HIS 14 14 14 HIS HIS DD . n 
C 1 15 GLN 15 15 15 GLN GLN DD . n 
C 1 16 LYS 16 16 16 LYS LYS DD . n 
C 1 17 LEU 17 17 17 LEU LEU DD . n 
C 1 18 VAL 18 18 18 VAL VAL DD . n 
C 1 19 PHE 19 19 19 PHE PHE DD . n 
C 1 20 PHE 20 20 20 PHE PHE DD . n 
C 1 21 ALA 21 21 21 ALA ALA DD . n 
C 1 22 GLU 22 22 22 GLU GLU DD . n 
C 1 23 DAS 23 23 23 DAS DAS DD . n 
C 1 24 VAL 24 24 24 VAL VAL DD . n 
C 1 25 GLY 25 25 25 GLY GLY DD . n 
C 1 26 SER 26 26 26 SER SER DD . n 
C 1 27 ASN 27 27 27 ASN ASN DD . n 
C 1 28 LYS 28 28 28 LYS LYS DD . n 
C 1 29 GLY 29 29 29 GLY GLY DD . n 
C 1 30 ALA 30 30 30 ALA ALA DD . n 
C 1 31 ILE 31 31 31 ILE ILE DD . n 
C 1 32 ILE 32 32 32 ILE ILE DD . n 
C 1 33 GLY 33 33 33 GLY GLY DD . n 
C 1 34 LEU 34 34 34 LEU LEU DD . n 
C 1 35 MET 35 35 35 MET MET DD . n 
C 1 36 VAL 36 36 36 VAL VAL DD . n 
C 1 37 GLY 37 37 37 GLY GLY DD . n 
C 1 38 GLY 38 38 38 GLY GLY DD . n 
C 1 39 VAL 39 39 39 VAL VAL DD . n 
C 1 40 VAL 40 40 40 VAL VAL DD . n 
C 1 41 ILE 41 41 41 ILE ILE DD . n 
C 1 42 ALA 42 42 42 ALA ALA DD . n 
D 1 1  ASP 1  1  ?  ?   ?   EE . n 
D 1 2  ALA 2  2  ?  ?   ?   EE . n 
D 1 3  GLU 3  3  ?  ?   ?   EE . n 
D 1 4  PHE 4  4  ?  ?   ?   EE . n 
D 1 5  ARG 5  5  ?  ?   ?   EE . n 
D 1 6  HIS 6  6  ?  ?   ?   EE . n 
D 1 7  ASP 7  7  ?  ?   ?   EE . n 
D 1 8  SER 8  8  ?  ?   ?   EE . n 
D 1 9  GLY 9  9  9  GLY GLY EE . n 
D 1 10 TYR 10 10 10 TYR TYR EE . n 
D 1 11 GLU 11 11 11 GLU GLU EE . n 
D 1 12 VAL 12 12 12 VAL VAL EE . n 
D 1 13 HIS 13 13 13 HIS HIS EE . n 
D 1 14 HIS 14 14 14 HIS HIS EE . n 
D 1 15 GLN 15 15 15 GLN GLN EE . n 
D 1 16 LYS 16 16 16 LYS LYS EE . n 
D 1 17 LEU 17 17 17 LEU LEU EE . n 
D 1 18 VAL 18 18 18 VAL VAL EE . n 
D 1 19 PHE 19 19 19 PHE PHE EE . n 
D 1 20 PHE 20 20 20 PHE PHE EE . n 
D 1 21 ALA 21 21 21 ALA ALA EE . n 
D 1 22 GLU 22 22 22 GLU GLU EE . n 
D 1 23 DAS 23 23 23 DAS DAS EE . n 
D 1 24 VAL 24 24 24 VAL VAL EE . n 
D 1 25 GLY 25 25 25 GLY GLY EE . n 
D 1 26 SER 26 26 26 SER SER EE . n 
D 1 27 ASN 27 27 27 ASN ASN EE . n 
D 1 28 LYS 28 28 28 LYS LYS EE . n 
D 1 29 GLY 29 29 29 GLY GLY EE . n 
D 1 30 ALA 30 30 30 ALA ALA EE . n 
D 1 31 ILE 31 31 31 ILE ILE EE . n 
D 1 32 ILE 32 32 32 ILE ILE EE . n 
D 1 33 GLY 33 33 33 GLY GLY EE . n 
D 1 34 LEU 34 34 34 LEU LEU EE . n 
D 1 35 MET 35 35 35 MET MET EE . n 
D 1 36 VAL 36 36 36 VAL VAL EE . n 
D 1 37 GLY 37 37 37 GLY GLY EE . n 
D 1 38 GLY 38 38 38 GLY GLY EE . n 
D 1 39 VAL 39 39 39 VAL VAL EE . n 
D 1 40 VAL 40 40 40 VAL VAL EE . n 
D 1 41 ILE 41 41 41 ILE ILE EE . n 
D 1 42 ALA 42 42 42 ALA ALA EE . n 
E 1 1  ASP 1  1  ?  ?   ?   FF . n 
E 1 2  ALA 2  2  ?  ?   ?   FF . n 
E 1 3  GLU 3  3  ?  ?   ?   FF . n 
E 1 4  PHE 4  4  ?  ?   ?   FF . n 
E 1 5  ARG 5  5  ?  ?   ?   FF . n 
E 1 6  HIS 6  6  ?  ?   ?   FF . n 
E 1 7  ASP 7  7  ?  ?   ?   FF . n 
E 1 8  SER 8  8  ?  ?   ?   FF . n 
E 1 9  GLY 9  9  9  GLY GLY FF . n 
E 1 10 TYR 10 10 10 TYR TYR FF . n 
E 1 11 GLU 11 11 11 GLU GLU FF . n 
E 1 12 VAL 12 12 12 VAL VAL FF . n 
E 1 13 HIS 13 13 13 HIS HIS FF . n 
E 1 14 HIS 14 14 14 HIS HIS FF . n 
E 1 15 GLN 15 15 15 GLN GLN FF . n 
E 1 16 LYS 16 16 16 LYS LYS FF . n 
E 1 17 LEU 17 17 17 LEU LEU FF . n 
E 1 18 VAL 18 18 18 VAL VAL FF . n 
E 1 19 PHE 19 19 19 PHE PHE FF . n 
E 1 20 PHE 20 20 20 PHE PHE FF . n 
E 1 21 ALA 21 21 21 ALA ALA FF . n 
E 1 22 GLU 22 22 22 GLU GLU FF . n 
E 1 23 DAS 23 23 23 DAS DAS FF . n 
E 1 24 VAL 24 24 24 VAL VAL FF . n 
E 1 25 GLY 25 25 25 GLY GLY FF . n 
E 1 26 SER 26 26 26 SER SER FF . n 
E 1 27 ASN 27 27 27 ASN ASN FF . n 
E 1 28 LYS 28 28 28 LYS LYS FF . n 
E 1 29 GLY 29 29 29 GLY GLY FF . n 
E 1 30 ALA 30 30 30 ALA ALA FF . n 
E 1 31 ILE 31 31 31 ILE ILE FF . n 
E 1 32 ILE 32 32 32 ILE ILE FF . n 
E 1 33 GLY 33 33 33 GLY GLY FF . n 
E 1 34 LEU 34 34 34 LEU LEU FF . n 
E 1 35 MET 35 35 35 MET MET FF . n 
E 1 36 VAL 36 36 36 VAL VAL FF . n 
E 1 37 GLY 37 37 37 GLY GLY FF . n 
E 1 38 GLY 38 38 38 GLY GLY FF . n 
E 1 39 VAL 39 39 39 VAL VAL FF . n 
E 1 40 VAL 40 40 40 VAL VAL FF . n 
E 1 41 ILE 41 41 41 ILE ILE FF . n 
E 1 42 ALA 42 42 42 ALA ALA FF . n 
F 1 1  ASP 1  1  ?  ?   ?   AA . n 
F 1 2  ALA 2  2  ?  ?   ?   AA . n 
F 1 3  GLU 3  3  ?  ?   ?   AA . n 
F 1 4  PHE 4  4  ?  ?   ?   AA . n 
F 1 5  ARG 5  5  ?  ?   ?   AA . n 
F 1 6  HIS 6  6  ?  ?   ?   AA . n 
F 1 7  ASP 7  7  ?  ?   ?   AA . n 
F 1 8  SER 8  8  ?  ?   ?   AA . n 
F 1 9  GLY 9  9  9  GLY GLY AA . n 
F 1 10 TYR 10 10 10 TYR TYR AA . n 
F 1 11 GLU 11 11 11 GLU GLU AA . n 
F 1 12 VAL 12 12 12 VAL VAL AA . n 
F 1 13 HIS 13 13 13 HIS HIS AA . n 
F 1 14 HIS 14 14 14 HIS HIS AA . n 
F 1 15 GLN 15 15 15 GLN GLN AA . n 
F 1 16 LYS 16 16 16 LYS LYS AA . n 
F 1 17 LEU 17 17 17 LEU LEU AA . n 
F 1 18 VAL 18 18 18 VAL VAL AA . n 
F 1 19 PHE 19 19 19 PHE PHE AA . n 
F 1 20 PHE 20 20 20 PHE PHE AA . n 
F 1 21 ALA 21 21 21 ALA ALA AA . n 
F 1 22 GLU 22 22 22 GLU GLU AA . n 
F 1 23 DAS 23 23 23 DAS DAS AA . n 
F 1 24 VAL 24 24 24 VAL VAL AA . n 
F 1 25 GLY 25 25 25 GLY GLY AA . n 
F 1 26 SER 26 26 26 SER SER AA . n 
F 1 27 ASN 27 27 27 ASN ASN AA . n 
F 1 28 LYS 28 28 28 LYS LYS AA . n 
F 1 29 GLY 29 29 29 GLY GLY AA . n 
F 1 30 ALA 30 30 30 ALA ALA AA . n 
F 1 31 ILE 31 31 31 ILE ILE AA . n 
F 1 32 ILE 32 32 32 ILE ILE AA . n 
F 1 33 GLY 33 33 33 GLY GLY AA . n 
F 1 34 LEU 34 34 34 LEU LEU AA . n 
F 1 35 MET 35 35 35 MET MET AA . n 
F 1 36 VAL 36 36 36 VAL VAL AA . n 
F 1 37 GLY 37 37 37 GLY GLY AA . n 
F 1 38 GLY 38 38 38 GLY GLY AA . n 
F 1 39 VAL 39 39 39 VAL VAL AA . n 
F 1 40 VAL 40 40 40 VAL VAL AA . n 
F 1 41 ILE 41 41 41 ILE ILE AA . n 
F 1 42 ALA 42 42 42 ALA ALA AA . n 
G 1 1  ASP 1  1  ?  ?   ?   A  . n 
G 1 2  ALA 2  2  ?  ?   ?   A  . n 
G 1 3  GLU 3  3  ?  ?   ?   A  . n 
G 1 4  PHE 4  4  ?  ?   ?   A  . n 
G 1 5  ARG 5  5  ?  ?   ?   A  . n 
G 1 6  HIS 6  6  ?  ?   ?   A  . n 
G 1 7  ASP 7  7  ?  ?   ?   A  . n 
G 1 8  SER 8  8  ?  ?   ?   A  . n 
G 1 9  GLY 9  9  9  GLY GLY A  . n 
G 1 10 TYR 10 10 10 TYR TYR A  . n 
G 1 11 GLU 11 11 11 GLU GLU A  . n 
G 1 12 VAL 12 12 12 VAL VAL A  . n 
G 1 13 HIS 13 13 13 HIS HIS A  . n 
G 1 14 HIS 14 14 14 HIS HIS A  . n 
G 1 15 GLN 15 15 15 GLN GLN A  . n 
G 1 16 LYS 16 16 16 LYS LYS A  . n 
G 1 17 LEU 17 17 17 LEU LEU A  . n 
G 1 18 VAL 18 18 18 VAL VAL A  . n 
G 1 19 PHE 19 19 19 PHE PHE A  . n 
G 1 20 PHE 20 20 20 PHE PHE A  . n 
G 1 21 ALA 21 21 21 ALA ALA A  . n 
G 1 22 GLU 22 22 22 GLU GLU A  . n 
G 1 23 DAS 23 23 23 DAS DAS A  . n 
G 1 24 VAL 24 24 24 VAL VAL A  . n 
G 1 25 GLY 25 25 25 GLY GLY A  . n 
G 1 26 SER 26 26 26 SER SER A  . n 
G 1 27 ASN 27 27 27 ASN ASN A  . n 
G 1 28 LYS 28 28 28 LYS LYS A  . n 
G 1 29 GLY 29 29 29 GLY GLY A  . n 
G 1 30 ALA 30 30 30 ALA ALA A  . n 
G 1 31 ILE 31 31 31 ILE ILE A  . n 
G 1 32 ILE 32 32 32 ILE ILE A  . n 
G 1 33 GLY 33 33 33 GLY GLY A  . n 
G 1 34 LEU 34 34 34 LEU LEU A  . n 
G 1 35 MET 35 35 35 MET MET A  . n 
G 1 36 VAL 36 36 36 VAL VAL A  . n 
G 1 37 GLY 37 37 37 GLY GLY A  . n 
G 1 38 GLY 38 38 38 GLY GLY A  . n 
G 1 39 VAL 39 39 39 VAL VAL A  . n 
G 1 40 VAL 40 40 40 VAL VAL A  . n 
G 1 41 ILE 41 41 41 ILE ILE A  . n 
G 1 42 ALA 42 42 42 ALA ALA A  . n 
H 1 1  ASP 1  1  ?  ?   ?   B  . n 
H 1 2  ALA 2  2  ?  ?   ?   B  . n 
H 1 3  GLU 3  3  ?  ?   ?   B  . n 
H 1 4  PHE 4  4  ?  ?   ?   B  . n 
H 1 5  ARG 5  5  ?  ?   ?   B  . n 
H 1 6  HIS 6  6  ?  ?   ?   B  . n 
H 1 7  ASP 7  7  ?  ?   ?   B  . n 
H 1 8  SER 8  8  ?  ?   ?   B  . n 
H 1 9  GLY 9  9  9  GLY GLY B  . n 
H 1 10 TYR 10 10 10 TYR TYR B  . n 
H 1 11 GLU 11 11 11 GLU GLU B  . n 
H 1 12 VAL 12 12 12 VAL VAL B  . n 
H 1 13 HIS 13 13 13 HIS HIS B  . n 
H 1 14 HIS 14 14 14 HIS HIS B  . n 
H 1 15 GLN 15 15 15 GLN GLN B  . n 
H 1 16 LYS 16 16 16 LYS LYS B  . n 
H 1 17 LEU 17 17 17 LEU LEU B  . n 
H 1 18 VAL 18 18 18 VAL VAL B  . n 
H 1 19 PHE 19 19 19 PHE PHE B  . n 
H 1 20 PHE 20 20 20 PHE PHE B  . n 
H 1 21 ALA 21 21 21 ALA ALA B  . n 
H 1 22 GLU 22 22 22 GLU GLU B  . n 
H 1 23 DAS 23 23 23 DAS DAS B  . n 
H 1 24 VAL 24 24 24 VAL VAL B  . n 
H 1 25 GLY 25 25 25 GLY GLY B  . n 
H 1 26 SER 26 26 26 SER SER B  . n 
H 1 27 ASN 27 27 27 ASN ASN B  . n 
H 1 28 LYS 28 28 28 LYS LYS B  . n 
H 1 29 GLY 29 29 29 GLY GLY B  . n 
H 1 30 ALA 30 30 30 ALA ALA B  . n 
H 1 31 ILE 31 31 31 ILE ILE B  . n 
H 1 32 ILE 32 32 32 ILE ILE B  . n 
H 1 33 GLY 33 33 33 GLY GLY B  . n 
H 1 34 LEU 34 34 34 LEU LEU B  . n 
H 1 35 MET 35 35 35 MET MET B  . n 
H 1 36 VAL 36 36 36 VAL VAL B  . n 
H 1 37 GLY 37 37 37 GLY GLY B  . n 
H 1 38 GLY 38 38 38 GLY GLY B  . n 
H 1 39 VAL 39 39 39 VAL VAL B  . n 
H 1 40 VAL 40 40 40 VAL VAL B  . n 
H 1 41 ILE 41 41 41 ILE ILE B  . n 
H 1 42 ALA 42 42 42 ALA ALA B  . n 
I 1 1  ASP 1  1  ?  ?   ?   C  . n 
I 1 2  ALA 2  2  ?  ?   ?   C  . n 
I 1 3  GLU 3  3  ?  ?   ?   C  . n 
I 1 4  PHE 4  4  ?  ?   ?   C  . n 
I 1 5  ARG 5  5  ?  ?   ?   C  . n 
I 1 6  HIS 6  6  ?  ?   ?   C  . n 
I 1 7  ASP 7  7  ?  ?   ?   C  . n 
I 1 8  SER 8  8  ?  ?   ?   C  . n 
I 1 9  GLY 9  9  9  GLY GLY C  . n 
I 1 10 TYR 10 10 10 TYR TYR C  . n 
I 1 11 GLU 11 11 11 GLU GLU C  . n 
I 1 12 VAL 12 12 12 VAL VAL C  . n 
I 1 13 HIS 13 13 13 HIS HIS C  . n 
I 1 14 HIS 14 14 14 HIS HIS C  . n 
I 1 15 GLN 15 15 15 GLN GLN C  . n 
I 1 16 LYS 16 16 16 LYS LYS C  . n 
I 1 17 LEU 17 17 17 LEU LEU C  . n 
I 1 18 VAL 18 18 18 VAL VAL C  . n 
I 1 19 PHE 19 19 19 PHE PHE C  . n 
I 1 20 PHE 20 20 20 PHE PHE C  . n 
I 1 21 ALA 21 21 21 ALA ALA C  . n 
I 1 22 GLU 22 22 22 GLU GLU C  . n 
I 1 23 DAS 23 23 23 DAS DAS C  . n 
I 1 24 VAL 24 24 24 VAL VAL C  . n 
I 1 25 GLY 25 25 25 GLY GLY C  . n 
I 1 26 SER 26 26 26 SER SER C  . n 
I 1 27 ASN 27 27 27 ASN ASN C  . n 
I 1 28 LYS 28 28 28 LYS LYS C  . n 
I 1 29 GLY 29 29 29 GLY GLY C  . n 
I 1 30 ALA 30 30 30 ALA ALA C  . n 
I 1 31 ILE 31 31 31 ILE ILE C  . n 
I 1 32 ILE 32 32 32 ILE ILE C  . n 
I 1 33 GLY 33 33 33 GLY GLY C  . n 
I 1 34 LEU 34 34 34 LEU LEU C  . n 
I 1 35 MET 35 35 35 MET MET C  . n 
I 1 36 VAL 36 36 36 VAL VAL C  . n 
I 1 37 GLY 37 37 37 GLY GLY C  . n 
I 1 38 GLY 38 38 38 GLY GLY C  . n 
I 1 39 VAL 39 39 39 VAL VAL C  . n 
I 1 40 VAL 40 40 40 VAL VAL C  . n 
I 1 41 ILE 41 41 41 ILE ILE C  . n 
I 1 42 ALA 42 42 42 ALA ALA C  . n 
J 1 1  ASP 1  1  ?  ?   ?   D  . n 
J 1 2  ALA 2  2  ?  ?   ?   D  . n 
J 1 3  GLU 3  3  ?  ?   ?   D  . n 
J 1 4  PHE 4  4  ?  ?   ?   D  . n 
J 1 5  ARG 5  5  ?  ?   ?   D  . n 
J 1 6  HIS 6  6  ?  ?   ?   D  . n 
J 1 7  ASP 7  7  ?  ?   ?   D  . n 
J 1 8  SER 8  8  ?  ?   ?   D  . n 
J 1 9  GLY 9  9  9  GLY GLY D  . n 
J 1 10 TYR 10 10 10 TYR TYR D  . n 
J 1 11 GLU 11 11 11 GLU GLU D  . n 
J 1 12 VAL 12 12 12 VAL VAL D  . n 
J 1 13 HIS 13 13 13 HIS HIS D  . n 
J 1 14 HIS 14 14 14 HIS HIS D  . n 
J 1 15 GLN 15 15 15 GLN GLN D  . n 
J 1 16 LYS 16 16 16 LYS LYS D  . n 
J 1 17 LEU 17 17 17 LEU LEU D  . n 
J 1 18 VAL 18 18 18 VAL VAL D  . n 
J 1 19 PHE 19 19 19 PHE PHE D  . n 
J 1 20 PHE 20 20 20 PHE PHE D  . n 
J 1 21 ALA 21 21 21 ALA ALA D  . n 
J 1 22 GLU 22 22 22 GLU GLU D  . n 
J 1 23 DAS 23 23 23 DAS DAS D  . n 
J 1 24 VAL 24 24 24 VAL VAL D  . n 
J 1 25 GLY 25 25 25 GLY GLY D  . n 
J 1 26 SER 26 26 26 SER SER D  . n 
J 1 27 ASN 27 27 27 ASN ASN D  . n 
J 1 28 LYS 28 28 28 LYS LYS D  . n 
J 1 29 GLY 29 29 29 GLY GLY D  . n 
J 1 30 ALA 30 30 30 ALA ALA D  . n 
J 1 31 ILE 31 31 31 ILE ILE D  . n 
J 1 32 ILE 32 32 32 ILE ILE D  . n 
J 1 33 GLY 33 33 33 GLY GLY D  . n 
J 1 34 LEU 34 34 34 LEU LEU D  . n 
J 1 35 MET 35 35 35 MET MET D  . n 
J 1 36 VAL 36 36 36 VAL VAL D  . n 
J 1 37 GLY 37 37 37 GLY GLY D  . n 
J 1 38 GLY 38 38 38 GLY GLY D  . n 
J 1 39 VAL 39 39 39 VAL VAL D  . n 
J 1 40 VAL 40 40 40 VAL VAL D  . n 
J 1 41 ILE 41 41 41 ILE ILE D  . n 
J 1 42 ALA 42 42 42 ALA ALA D  . n 
K 1 1  ASP 1  1  ?  ?   ?   E  . n 
K 1 2  ALA 2  2  ?  ?   ?   E  . n 
K 1 3  GLU 3  3  ?  ?   ?   E  . n 
K 1 4  PHE 4  4  ?  ?   ?   E  . n 
K 1 5  ARG 5  5  ?  ?   ?   E  . n 
K 1 6  HIS 6  6  ?  ?   ?   E  . n 
K 1 7  ASP 7  7  ?  ?   ?   E  . n 
K 1 8  SER 8  8  ?  ?   ?   E  . n 
K 1 9  GLY 9  9  9  GLY GLY E  . n 
K 1 10 TYR 10 10 10 TYR TYR E  . n 
K 1 11 GLU 11 11 11 GLU GLU E  . n 
K 1 12 VAL 12 12 12 VAL VAL E  . n 
K 1 13 HIS 13 13 13 HIS HIS E  . n 
K 1 14 HIS 14 14 14 HIS HIS E  . n 
K 1 15 GLN 15 15 15 GLN GLN E  . n 
K 1 16 LYS 16 16 16 LYS LYS E  . n 
K 1 17 LEU 17 17 17 LEU LEU E  . n 
K 1 18 VAL 18 18 18 VAL VAL E  . n 
K 1 19 PHE 19 19 19 PHE PHE E  . n 
K 1 20 PHE 20 20 20 PHE PHE E  . n 
K 1 21 ALA 21 21 21 ALA ALA E  . n 
K 1 22 GLU 22 22 22 GLU GLU E  . n 
K 1 23 DAS 23 23 23 DAS DAS E  . n 
K 1 24 VAL 24 24 24 VAL VAL E  . n 
K 1 25 GLY 25 25 25 GLY GLY E  . n 
K 1 26 SER 26 26 26 SER SER E  . n 
K 1 27 ASN 27 27 27 ASN ASN E  . n 
K 1 28 LYS 28 28 28 LYS LYS E  . n 
K 1 29 GLY 29 29 29 GLY GLY E  . n 
K 1 30 ALA 30 30 30 ALA ALA E  . n 
K 1 31 ILE 31 31 31 ILE ILE E  . n 
K 1 32 ILE 32 32 32 ILE ILE E  . n 
K 1 33 GLY 33 33 33 GLY GLY E  . n 
K 1 34 LEU 34 34 34 LEU LEU E  . n 
K 1 35 MET 35 35 35 MET MET E  . n 
K 1 36 VAL 36 36 36 VAL VAL E  . n 
K 1 37 GLY 37 37 37 GLY GLY E  . n 
K 1 38 GLY 38 38 38 GLY GLY E  . n 
K 1 39 VAL 39 39 39 VAL VAL E  . n 
K 1 40 VAL 40 40 40 VAL VAL E  . n 
K 1 41 ILE 41 41 41 ILE ILE E  . n 
K 1 42 ALA 42 42 42 ALA ALA E  . n 
L 1 1  ASP 1  1  ?  ?   ?   F  . n 
L 1 2  ALA 2  2  ?  ?   ?   F  . n 
L 1 3  GLU 3  3  ?  ?   ?   F  . n 
L 1 4  PHE 4  4  ?  ?   ?   F  . n 
L 1 5  ARG 5  5  ?  ?   ?   F  . n 
L 1 6  HIS 6  6  ?  ?   ?   F  . n 
L 1 7  ASP 7  7  ?  ?   ?   F  . n 
L 1 8  SER 8  8  ?  ?   ?   F  . n 
L 1 9  GLY 9  9  9  GLY GLY F  . n 
L 1 10 TYR 10 10 10 TYR TYR F  . n 
L 1 11 GLU 11 11 11 GLU GLU F  . n 
L 1 12 VAL 12 12 12 VAL VAL F  . n 
L 1 13 HIS 13 13 13 HIS HIS F  . n 
L 1 14 HIS 14 14 14 HIS HIS F  . n 
L 1 15 GLN 15 15 15 GLN GLN F  . n 
L 1 16 LYS 16 16 16 LYS LYS F  . n 
L 1 17 LEU 17 17 17 LEU LEU F  . n 
L 1 18 VAL 18 18 18 VAL VAL F  . n 
L 1 19 PHE 19 19 19 PHE PHE F  . n 
L 1 20 PHE 20 20 20 PHE PHE F  . n 
L 1 21 ALA 21 21 21 ALA ALA F  . n 
L 1 22 GLU 22 22 22 GLU GLU F  . n 
L 1 23 DAS 23 23 23 DAS DAS F  . n 
L 1 24 VAL 24 24 24 VAL VAL F  . n 
L 1 25 GLY 25 25 25 GLY GLY F  . n 
L 1 26 SER 26 26 26 SER SER F  . n 
L 1 27 ASN 27 27 27 ASN ASN F  . n 
L 1 28 LYS 28 28 28 LYS LYS F  . n 
L 1 29 GLY 29 29 29 GLY GLY F  . n 
L 1 30 ALA 30 30 30 ALA ALA F  . n 
L 1 31 ILE 31 31 31 ILE ILE F  . n 
L 1 32 ILE 32 32 32 ILE ILE F  . n 
L 1 33 GLY 33 33 33 GLY GLY F  . n 
L 1 34 LEU 34 34 34 LEU LEU F  . n 
L 1 35 MET 35 35 35 MET MET F  . n 
L 1 36 VAL 36 36 36 VAL VAL F  . n 
L 1 37 GLY 37 37 37 GLY GLY F  . n 
L 1 38 GLY 38 38 38 GLY GLY F  . n 
L 1 39 VAL 39 39 39 VAL VAL F  . n 
L 1 40 VAL 40 40 40 VAL VAL F  . n 
L 1 41 ILE 41 41 41 ILE ILE F  . n 
L 1 42 ALA 42 42 42 ALA ALA F  . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JB0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JB0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JB0 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JB0 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 3060 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.364 ? 4116 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.428 ? 444  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.055 ? 468  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.002 ? 528  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JB0 
_struct.title                        'Cryo-EM structure of the class II amyloid-beta 42 fibril containing a D-Asp at position 23' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JB0 
_struct_keywords.text            'aggregation, PROTEIN FIBRIL' 
_struct_keywords.pdbx_keywords   'PROTEIN FIBRIL' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 1 ? 
H N N 1 ? 
I N N 1 ? 
J N N 1 ? 
K N N 1 ? 
L N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A4_HUMAN 
_struct_ref.pdbx_db_accession          P05067 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 
_struct_ref.pdbx_align_begin           672 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1  1 9JB0 CC 1 ? 42 ? P05067 672 ? 713 ? 1 42 
2  1 9JB0 BB 1 ? 42 ? P05067 672 ? 713 ? 1 42 
3  1 9JB0 DD 1 ? 42 ? P05067 672 ? 713 ? 1 42 
4  1 9JB0 EE 1 ? 42 ? P05067 672 ? 713 ? 1 42 
5  1 9JB0 FF 1 ? 42 ? P05067 672 ? 713 ? 1 42 
6  1 9JB0 AA 1 ? 42 ? P05067 672 ? 713 ? 1 42 
7  1 9JB0 A  1 ? 42 ? P05067 672 ? 713 ? 1 42 
8  1 9JB0 B  1 ? 42 ? P05067 672 ? 713 ? 1 42 
9  1 9JB0 C  1 ? 42 ? P05067 672 ? 713 ? 1 42 
10 1 9JB0 D  1 ? 42 ? P05067 672 ? 713 ? 1 42 
11 1 9JB0 E  1 ? 42 ? P05067 672 ? 713 ? 1 42 
12 1 9JB0 F  1 ? 42 ? P05067 672 ? 713 ? 1 42 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1  9JB0 DAS CC 23 ? UNP P05067 ASP 694 'modified residue' 23 1  
2  9JB0 DAS BB 23 ? UNP P05067 ASP 694 'modified residue' 23 2  
3  9JB0 DAS DD 23 ? UNP P05067 ASP 694 'modified residue' 23 3  
4  9JB0 DAS EE 23 ? UNP P05067 ASP 694 'modified residue' 23 4  
5  9JB0 DAS FF 23 ? UNP P05067 ASP 694 'modified residue' 23 5  
6  9JB0 DAS AA 23 ? UNP P05067 ASP 694 'modified residue' 23 6  
7  9JB0 DAS A  23 ? UNP P05067 ASP 694 'modified residue' 23 7  
8  9JB0 DAS B  23 ? UNP P05067 ASP 694 'modified residue' 23 8  
9  9JB0 DAS C  23 ? UNP P05067 ASP 694 'modified residue' 23 9  
10 9JB0 DAS D  23 ? UNP P05067 ASP 694 'modified residue' 23 10 
11 9JB0 DAS E  23 ? UNP P05067 ASP 694 'modified residue' 23 11 
12 9JB0 DAS F  23 ? UNP P05067 ASP 694 'modified residue' 23 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dodecameric 
_pdbx_struct_assembly.oligomeric_count     12 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A GLU 22 C ? ? ? 1_555 A DAS 23 N ? ? CC GLU 22 CC DAS 23 1_555 ? ? ? ? ? ? ? 1.326 ? ? 
covale2  covale both ? A DAS 23 C ? ? ? 1_555 A VAL 24 N ? ? CC DAS 23 CC VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale3  covale both ? B GLU 22 C ? ? ? 1_555 B DAS 23 N ? ? BB GLU 22 BB DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale4  covale both ? B DAS 23 C ? ? ? 1_555 B VAL 24 N ? ? BB DAS 23 BB VAL 24 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale5  covale both ? C GLU 22 C ? ? ? 1_555 C DAS 23 N ? ? DD GLU 22 DD DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale6  covale both ? C DAS 23 C ? ? ? 1_555 C VAL 24 N ? ? DD DAS 23 DD VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale7  covale both ? D GLU 22 C ? ? ? 1_555 D DAS 23 N ? ? EE GLU 22 EE DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale8  covale both ? D DAS 23 C ? ? ? 1_555 D VAL 24 N ? ? EE DAS 23 EE VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale9  covale both ? E GLU 22 C ? ? ? 1_555 E DAS 23 N ? ? FF GLU 22 FF DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale10 covale both ? E DAS 23 C ? ? ? 1_555 E VAL 24 N ? ? FF DAS 23 FF VAL 24 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale11 covale both ? F GLU 22 C ? ? ? 1_555 F DAS 23 N ? ? AA GLU 22 AA DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale12 covale both ? F DAS 23 C ? ? ? 1_555 F VAL 24 N ? ? AA DAS 23 AA VAL 24 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale13 covale both ? G GLU 22 C ? ? ? 1_555 G DAS 23 N ? ? A  GLU 22 A  DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale14 covale both ? G DAS 23 C ? ? ? 1_555 G VAL 24 N ? ? A  DAS 23 A  VAL 24 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale15 covale both ? H GLU 22 C ? ? ? 1_555 H DAS 23 N ? ? B  GLU 22 B  DAS 23 1_555 ? ? ? ? ? ? ? 1.326 ? ? 
covale16 covale both ? H DAS 23 C ? ? ? 1_555 H VAL 24 N ? ? B  DAS 23 B  VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale17 covale both ? I GLU 22 C ? ? ? 1_555 I DAS 23 N ? ? C  GLU 22 C  DAS 23 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale18 covale both ? I DAS 23 C ? ? ? 1_555 I VAL 24 N ? ? C  DAS 23 C  VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale19 covale both ? J GLU 22 C ? ? ? 1_555 J DAS 23 N ? ? D  GLU 22 D  DAS 23 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale20 covale both ? J DAS 23 C ? ? ? 1_555 J VAL 24 N ? ? D  DAS 23 D  VAL 24 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale21 covale both ? K GLU 22 C ? ? ? 1_555 K DAS 23 N ? ? E  GLU 22 E  DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale22 covale both ? K DAS 23 C ? ? ? 1_555 K VAL 24 N ? ? E  DAS 23 E  VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale23 covale both ? L GLU 22 C ? ? ? 1_555 L DAS 23 N ? ? F  GLU 22 F  DAS 23 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale24 covale both ? L DAS 23 C ? ? ? 1_555 L VAL 24 N ? ? F  DAS 23 F  VAL 24 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 6 ? 
AA3 ? 6 ? 
AA4 ? 6 ? 
AA5 ? 6 ? 
AA6 ? 6 ? 
AA7 ? 6 ? 
AA8 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA1 4 5 ? parallel 
AA1 5 6 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
AA2 4 5 ? parallel 
AA2 5 6 ? parallel 
AA3 1 2 ? parallel 
AA3 2 3 ? parallel 
AA3 3 4 ? parallel 
AA3 4 5 ? parallel 
AA3 5 6 ? parallel 
AA4 1 2 ? parallel 
AA4 2 3 ? parallel 
AA4 3 4 ? parallel 
AA4 4 5 ? parallel 
AA4 5 6 ? parallel 
AA5 1 2 ? parallel 
AA5 2 3 ? parallel 
AA5 3 4 ? parallel 
AA5 4 5 ? parallel 
AA5 5 6 ? parallel 
AA6 1 2 ? parallel 
AA6 2 3 ? parallel 
AA6 3 4 ? parallel 
AA6 4 5 ? parallel 
AA6 5 6 ? parallel 
AA7 1 2 ? parallel 
AA7 2 3 ? parallel 
AA7 3 4 ? parallel 
AA7 4 5 ? parallel 
AA7 5 6 ? parallel 
AA8 1 2 ? parallel 
AA8 2 3 ? parallel 
AA8 3 4 ? parallel 
AA8 4 5 ? parallel 
AA8 5 6 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR E 10 ? HIS E 13 ? TYR FF 10 HIS FF 13 
AA1 2 TYR D 10 ? HIS D 13 ? TYR EE 10 HIS EE 13 
AA1 3 TYR C 10 ? HIS C 13 ? TYR DD 10 HIS DD 13 
AA1 4 TYR A 10 ? HIS A 13 ? TYR CC 10 HIS CC 13 
AA1 5 TYR B 10 ? HIS B 13 ? TYR BB 10 HIS BB 13 
AA1 6 TYR F 10 ? HIS F 13 ? TYR AA 10 HIS AA 13 
AA2 1 GLN E 15 ? ALA E 21 ? GLN FF 15 ALA FF 21 
AA2 2 GLN D 15 ? ALA D 21 ? GLN EE 15 ALA EE 21 
AA2 3 GLN C 15 ? ALA C 21 ? GLN DD 15 ALA DD 21 
AA2 4 GLN A 15 ? ALA A 21 ? GLN CC 15 ALA CC 21 
AA2 5 GLN B 15 ? ALA B 21 ? GLN BB 15 ALA BB 21 
AA2 6 GLN F 15 ? ALA F 21 ? GLN AA 15 ALA AA 21 
AA3 1 ALA E 30 ? ILE E 32 ? ALA FF 30 ILE FF 32 
AA3 2 ALA D 30 ? ILE D 32 ? ALA EE 30 ILE EE 32 
AA3 3 ALA C 30 ? ILE C 32 ? ALA DD 30 ILE DD 32 
AA3 4 ALA A 30 ? ILE A 32 ? ALA CC 30 ILE CC 32 
AA3 5 ALA B 30 ? ILE B 32 ? ALA BB 30 ILE BB 32 
AA3 6 ALA F 30 ? ILE F 32 ? ALA AA 30 ILE AA 32 
AA4 1 LEU E 34 ? ILE E 41 ? LEU FF 34 ILE FF 41 
AA4 2 LEU D 34 ? ILE D 41 ? LEU EE 34 ILE EE 41 
AA4 3 LEU C 34 ? ILE C 41 ? LEU DD 34 ILE DD 41 
AA4 4 LEU A 34 ? ILE A 41 ? LEU CC 34 ILE CC 41 
AA4 5 LEU B 34 ? ILE B 41 ? LEU BB 34 ILE BB 41 
AA4 6 LEU F 34 ? ILE F 41 ? LEU AA 34 ILE AA 41 
AA5 1 TYR G 10 ? HIS G 13 ? TYR A  10 HIS A  13 
AA5 2 TYR H 10 ? HIS H 13 ? TYR B  10 HIS B  13 
AA5 3 TYR I 10 ? HIS I 13 ? TYR C  10 HIS C  13 
AA5 4 TYR J 10 ? HIS J 13 ? TYR D  10 HIS D  13 
AA5 5 TYR K 10 ? HIS K 13 ? TYR E  10 HIS E  13 
AA5 6 TYR L 10 ? HIS L 13 ? TYR F  10 HIS F  13 
AA6 1 GLN G 15 ? ALA G 21 ? GLN A  15 ALA A  21 
AA6 2 GLN H 15 ? ALA H 21 ? GLN B  15 ALA B  21 
AA6 3 GLN I 15 ? ALA I 21 ? GLN C  15 ALA C  21 
AA6 4 GLN J 15 ? ALA J 21 ? GLN D  15 ALA D  21 
AA6 5 GLN K 15 ? ALA K 21 ? GLN E  15 ALA E  21 
AA6 6 GLN L 15 ? ALA L 21 ? GLN F  15 ALA F  21 
AA7 1 ALA G 30 ? ILE G 32 ? ALA A  30 ILE A  32 
AA7 2 ALA H 30 ? ILE H 32 ? ALA B  30 ILE B  32 
AA7 3 ALA I 30 ? ILE I 32 ? ALA C  30 ILE C  32 
AA7 4 ALA J 30 ? ILE J 32 ? ALA D  30 ILE D  32 
AA7 5 ALA K 30 ? ILE K 32 ? ALA E  30 ILE E  32 
AA7 6 ALA L 30 ? ILE L 32 ? ALA F  30 ILE F  32 
AA8 1 LEU G 34 ? ILE G 41 ? LEU A  34 ILE A  41 
AA8 2 LEU H 34 ? ILE H 41 ? LEU B  34 ILE B  41 
AA8 3 LEU I 34 ? ILE I 41 ? LEU C  34 ILE C  41 
AA8 4 LEU J 34 ? ILE J 41 ? LEU D  34 ILE D  41 
AA8 5 LEU K 34 ? ILE K 41 ? LEU E  34 ILE E  41 
AA8 6 LEU L 34 ? ILE L 41 ? LEU F  34 ILE F  41 
# 
_pdbx_entry_details.entry_id                   9JB0 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JB0 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JB0 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               250544 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Class II amyloid-beta 42 fibril containing a D-Asp at position 23' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JB0 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             1700 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9JB0 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JB0 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 CC ASP 1 ? A ASP 1 
2  1 Y 1 CC ALA 2 ? A ALA 2 
3  1 Y 1 CC GLU 3 ? A GLU 3 
4  1 Y 1 CC PHE 4 ? A PHE 4 
5  1 Y 1 CC ARG 5 ? A ARG 5 
6  1 Y 1 CC HIS 6 ? A HIS 6 
7  1 Y 1 CC ASP 7 ? A ASP 7 
8  1 Y 1 CC SER 8 ? A SER 8 
9  1 Y 1 BB ASP 1 ? B ASP 1 
10 1 Y 1 BB ALA 2 ? B ALA 2 
11 1 Y 1 BB GLU 3 ? B GLU 3 
12 1 Y 1 BB PHE 4 ? B PHE 4 
13 1 Y 1 BB ARG 5 ? B ARG 5 
14 1 Y 1 BB HIS 6 ? B HIS 6 
15 1 Y 1 BB ASP 7 ? B ASP 7 
16 1 Y 1 BB SER 8 ? B SER 8 
17 1 Y 1 DD ASP 1 ? C ASP 1 
18 1 Y 1 DD ALA 2 ? C ALA 2 
19 1 Y 1 DD GLU 3 ? C GLU 3 
20 1 Y 1 DD PHE 4 ? C PHE 4 
21 1 Y 1 DD ARG 5 ? C ARG 5 
22 1 Y 1 DD HIS 6 ? C HIS 6 
23 1 Y 1 DD ASP 7 ? C ASP 7 
24 1 Y 1 DD SER 8 ? C SER 8 
25 1 Y 1 EE ASP 1 ? D ASP 1 
26 1 Y 1 EE ALA 2 ? D ALA 2 
27 1 Y 1 EE GLU 3 ? D GLU 3 
28 1 Y 1 EE PHE 4 ? D PHE 4 
29 1 Y 1 EE ARG 5 ? D ARG 5 
30 1 Y 1 EE HIS 6 ? D HIS 6 
31 1 Y 1 EE ASP 7 ? D ASP 7 
32 1 Y 1 EE SER 8 ? D SER 8 
33 1 Y 1 FF ASP 1 ? E ASP 1 
34 1 Y 1 FF ALA 2 ? E ALA 2 
35 1 Y 1 FF GLU 3 ? E GLU 3 
36 1 Y 1 FF PHE 4 ? E PHE 4 
37 1 Y 1 FF ARG 5 ? E ARG 5 
38 1 Y 1 FF HIS 6 ? E HIS 6 
39 1 Y 1 FF ASP 7 ? E ASP 7 
40 1 Y 1 FF SER 8 ? E SER 8 
41 1 Y 1 AA ASP 1 ? F ASP 1 
42 1 Y 1 AA ALA 2 ? F ALA 2 
43 1 Y 1 AA GLU 3 ? F GLU 3 
44 1 Y 1 AA PHE 4 ? F PHE 4 
45 1 Y 1 AA ARG 5 ? F ARG 5 
46 1 Y 1 AA HIS 6 ? F HIS 6 
47 1 Y 1 AA ASP 7 ? F ASP 7 
48 1 Y 1 AA SER 8 ? F SER 8 
49 1 Y 1 A  ASP 1 ? G ASP 1 
50 1 Y 1 A  ALA 2 ? G ALA 2 
51 1 Y 1 A  GLU 3 ? G GLU 3 
52 1 Y 1 A  PHE 4 ? G PHE 4 
53 1 Y 1 A  ARG 5 ? G ARG 5 
54 1 Y 1 A  HIS 6 ? G HIS 6 
55 1 Y 1 A  ASP 7 ? G ASP 7 
56 1 Y 1 A  SER 8 ? G SER 8 
57 1 Y 1 B  ASP 1 ? H ASP 1 
58 1 Y 1 B  ALA 2 ? H ALA 2 
59 1 Y 1 B  GLU 3 ? H GLU 3 
60 1 Y 1 B  PHE 4 ? H PHE 4 
61 1 Y 1 B  ARG 5 ? H ARG 5 
62 1 Y 1 B  HIS 6 ? H HIS 6 
63 1 Y 1 B  ASP 7 ? H ASP 7 
64 1 Y 1 B  SER 8 ? H SER 8 
65 1 Y 1 C  ASP 1 ? I ASP 1 
66 1 Y 1 C  ALA 2 ? I ALA 2 
67 1 Y 1 C  GLU 3 ? I GLU 3 
68 1 Y 1 C  PHE 4 ? I PHE 4 
69 1 Y 1 C  ARG 5 ? I ARG 5 
70 1 Y 1 C  HIS 6 ? I HIS 6 
71 1 Y 1 C  ASP 7 ? I ASP 7 
72 1 Y 1 C  SER 8 ? I SER 8 
73 1 Y 1 D  ASP 1 ? J ASP 1 
74 1 Y 1 D  ALA 2 ? J ALA 2 
75 1 Y 1 D  GLU 3 ? J GLU 3 
76 1 Y 1 D  PHE 4 ? J PHE 4 
77 1 Y 1 D  ARG 5 ? J ARG 5 
78 1 Y 1 D  HIS 6 ? J HIS 6 
79 1 Y 1 D  ASP 7 ? J ASP 7 
80 1 Y 1 D  SER 8 ? J SER 8 
81 1 Y 1 E  ASP 1 ? K ASP 1 
82 1 Y 1 E  ALA 2 ? K ALA 2 
83 1 Y 1 E  GLU 3 ? K GLU 3 
84 1 Y 1 E  PHE 4 ? K PHE 4 
85 1 Y 1 E  ARG 5 ? K ARG 5 
86 1 Y 1 E  HIS 6 ? K HIS 6 
87 1 Y 1 E  ASP 7 ? K ASP 7 
88 1 Y 1 E  SER 8 ? K SER 8 
89 1 Y 1 F  ASP 1 ? L ASP 1 
90 1 Y 1 F  ALA 2 ? L ALA 2 
91 1 Y 1 F  GLU 3 ? L GLU 3 
92 1 Y 1 F  PHE 4 ? L PHE 4 
93 1 Y 1 F  ARG 5 ? L ARG 5 
94 1 Y 1 F  HIS 6 ? L HIS 6 
95 1 Y 1 F  ASP 7 ? L ASP 7 
96 1 Y 1 F  SER 8 ? L SER 8 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
DAS N    N N N 74  
DAS CA   C N R 75  
DAS C    C N N 76  
DAS O    O N N 77  
DAS CB   C N N 78  
DAS CG   C N N 79  
DAS OD1  O N N 80  
DAS OD2  O N N 81  
DAS OXT  O N N 82  
DAS H    H N N 83  
DAS H2   H N N 84  
DAS HA   H N N 85  
DAS HB2  H N N 86  
DAS HB3  H N N 87  
DAS HD2  H N N 88  
DAS HXT  H N N 89  
GLN N    N N N 90  
GLN CA   C N S 91  
GLN C    C N N 92  
GLN O    O N N 93  
GLN CB   C N N 94  
GLN CG   C N N 95  
GLN CD   C N N 96  
GLN OE1  O N N 97  
GLN NE2  N N N 98  
GLN OXT  O N N 99  
GLN H    H N N 100 
GLN H2   H N N 101 
GLN HA   H N N 102 
GLN HB2  H N N 103 
GLN HB3  H N N 104 
GLN HG2  H N N 105 
GLN HG3  H N N 106 
GLN HE21 H N N 107 
GLN HE22 H N N 108 
GLN HXT  H N N 109 
GLU N    N N N 110 
GLU CA   C N S 111 
GLU C    C N N 112 
GLU O    O N N 113 
GLU CB   C N N 114 
GLU CG   C N N 115 
GLU CD   C N N 116 
GLU OE1  O N N 117 
GLU OE2  O N N 118 
GLU OXT  O N N 119 
GLU H    H N N 120 
GLU H2   H N N 121 
GLU HA   H N N 122 
GLU HB2  H N N 123 
GLU HB3  H N N 124 
GLU HG2  H N N 125 
GLU HG3  H N N 126 
GLU HE2  H N N 127 
GLU HXT  H N N 128 
GLY N    N N N 129 
GLY CA   C N N 130 
GLY C    C N N 131 
GLY O    O N N 132 
GLY OXT  O N N 133 
GLY H    H N N 134 
GLY H2   H N N 135 
GLY HA2  H N N 136 
GLY HA3  H N N 137 
GLY HXT  H N N 138 
HIS N    N N N 139 
HIS CA   C N S 140 
HIS C    C N N 141 
HIS O    O N N 142 
HIS CB   C N N 143 
HIS CG   C Y N 144 
HIS ND1  N Y N 145 
HIS CD2  C Y N 146 
HIS CE1  C Y N 147 
HIS NE2  N Y N 148 
HIS OXT  O N N 149 
HIS H    H N N 150 
HIS H2   H N N 151 
HIS HA   H N N 152 
HIS HB2  H N N 153 
HIS HB3  H N N 154 
HIS HD1  H N N 155 
HIS HD2  H N N 156 
HIS HE1  H N N 157 
HIS HE2  H N N 158 
HIS HXT  H N N 159 
ILE N    N N N 160 
ILE CA   C N S 161 
ILE C    C N N 162 
ILE O    O N N 163 
ILE CB   C N S 164 
ILE CG1  C N N 165 
ILE CG2  C N N 166 
ILE CD1  C N N 167 
ILE OXT  O N N 168 
ILE H    H N N 169 
ILE H2   H N N 170 
ILE HA   H N N 171 
ILE HB   H N N 172 
ILE HG12 H N N 173 
ILE HG13 H N N 174 
ILE HG21 H N N 175 
ILE HG22 H N N 176 
ILE HG23 H N N 177 
ILE HD11 H N N 178 
ILE HD12 H N N 179 
ILE HD13 H N N 180 
ILE HXT  H N N 181 
LEU N    N N N 182 
LEU CA   C N S 183 
LEU C    C N N 184 
LEU O    O N N 185 
LEU CB   C N N 186 
LEU CG   C N N 187 
LEU CD1  C N N 188 
LEU CD2  C N N 189 
LEU OXT  O N N 190 
LEU H    H N N 191 
LEU H2   H N N 192 
LEU HA   H N N 193 
LEU HB2  H N N 194 
LEU HB3  H N N 195 
LEU HG   H N N 196 
LEU HD11 H N N 197 
LEU HD12 H N N 198 
LEU HD13 H N N 199 
LEU HD21 H N N 200 
LEU HD22 H N N 201 
LEU HD23 H N N 202 
LEU HXT  H N N 203 
LYS N    N N N 204 
LYS CA   C N S 205 
LYS C    C N N 206 
LYS O    O N N 207 
LYS CB   C N N 208 
LYS CG   C N N 209 
LYS CD   C N N 210 
LYS CE   C N N 211 
LYS NZ   N N N 212 
LYS OXT  O N N 213 
LYS H    H N N 214 
LYS H2   H N N 215 
LYS HA   H N N 216 
LYS HB2  H N N 217 
LYS HB3  H N N 218 
LYS HG2  H N N 219 
LYS HG3  H N N 220 
LYS HD2  H N N 221 
LYS HD3  H N N 222 
LYS HE2  H N N 223 
LYS HE3  H N N 224 
LYS HZ1  H N N 225 
LYS HZ2  H N N 226 
LYS HZ3  H N N 227 
LYS HXT  H N N 228 
MET N    N N N 229 
MET CA   C N S 230 
MET C    C N N 231 
MET O    O N N 232 
MET CB   C N N 233 
MET CG   C N N 234 
MET SD   S N N 235 
MET CE   C N N 236 
MET OXT  O N N 237 
MET H    H N N 238 
MET H2   H N N 239 
MET HA   H N N 240 
MET HB2  H N N 241 
MET HB3  H N N 242 
MET HG2  H N N 243 
MET HG3  H N N 244 
MET HE1  H N N 245 
MET HE2  H N N 246 
MET HE3  H N N 247 
MET HXT  H N N 248 
PHE N    N N N 249 
PHE CA   C N S 250 
PHE C    C N N 251 
PHE O    O N N 252 
PHE CB   C N N 253 
PHE CG   C Y N 254 
PHE CD1  C Y N 255 
PHE CD2  C Y N 256 
PHE CE1  C Y N 257 
PHE CE2  C Y N 258 
PHE CZ   C Y N 259 
PHE OXT  O N N 260 
PHE H    H N N 261 
PHE H2   H N N 262 
PHE HA   H N N 263 
PHE HB2  H N N 264 
PHE HB3  H N N 265 
PHE HD1  H N N 266 
PHE HD2  H N N 267 
PHE HE1  H N N 268 
PHE HE2  H N N 269 
PHE HZ   H N N 270 
PHE HXT  H N N 271 
SER N    N N N 272 
SER CA   C N S 273 
SER C    C N N 274 
SER O    O N N 275 
SER CB   C N N 276 
SER OG   O N N 277 
SER OXT  O N N 278 
SER H    H N N 279 
SER H2   H N N 280 
SER HA   H N N 281 
SER HB2  H N N 282 
SER HB3  H N N 283 
SER HG   H N N 284 
SER HXT  H N N 285 
TYR N    N N N 286 
TYR CA   C N S 287 
TYR C    C N N 288 
TYR O    O N N 289 
TYR CB   C N N 290 
TYR CG   C Y N 291 
TYR CD1  C Y N 292 
TYR CD2  C Y N 293 
TYR CE1  C Y N 294 
TYR CE2  C Y N 295 
TYR CZ   C Y N 296 
TYR OH   O N N 297 
TYR OXT  O N N 298 
TYR H    H N N 299 
TYR H2   H N N 300 
TYR HA   H N N 301 
TYR HB2  H N N 302 
TYR HB3  H N N 303 
TYR HD1  H N N 304 
TYR HD2  H N N 305 
TYR HE1  H N N 306 
TYR HE2  H N N 307 
TYR HH   H N N 308 
TYR HXT  H N N 309 
VAL N    N N N 310 
VAL CA   C N S 311 
VAL C    C N N 312 
VAL O    O N N 313 
VAL CB   C N N 314 
VAL CG1  C N N 315 
VAL CG2  C N N 316 
VAL OXT  O N N 317 
VAL H    H N N 318 
VAL H2   H N N 319 
VAL HA   H N N 320 
VAL HB   H N N 321 
VAL HG11 H N N 322 
VAL HG12 H N N 323 
VAL HG13 H N N 324 
VAL HG21 H N N 325 
VAL HG22 H N N 326 
VAL HG23 H N N 327 
VAL HXT  H N N 328 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
DAS N   CA   sing N N 70  
DAS N   H    sing N N 71  
DAS N   H2   sing N N 72  
DAS CA  C    sing N N 73  
DAS CA  CB   sing N N 74  
DAS CA  HA   sing N N 75  
DAS C   O    doub N N 76  
DAS C   OXT  sing N N 77  
DAS CB  CG   sing N N 78  
DAS CB  HB2  sing N N 79  
DAS CB  HB3  sing N N 80  
DAS CG  OD1  doub N N 81  
DAS CG  OD2  sing N N 82  
DAS OD2 HD2  sing N N 83  
DAS OXT HXT  sing N N 84  
GLN N   CA   sing N N 85  
GLN N   H    sing N N 86  
GLN N   H2   sing N N 87  
GLN CA  C    sing N N 88  
GLN CA  CB   sing N N 89  
GLN CA  HA   sing N N 90  
GLN C   O    doub N N 91  
GLN C   OXT  sing N N 92  
GLN CB  CG   sing N N 93  
GLN CB  HB2  sing N N 94  
GLN CB  HB3  sing N N 95  
GLN CG  CD   sing N N 96  
GLN CG  HG2  sing N N 97  
GLN CG  HG3  sing N N 98  
GLN CD  OE1  doub N N 99  
GLN CD  NE2  sing N N 100 
GLN NE2 HE21 sing N N 101 
GLN NE2 HE22 sing N N 102 
GLN OXT HXT  sing N N 103 
GLU N   CA   sing N N 104 
GLU N   H    sing N N 105 
GLU N   H2   sing N N 106 
GLU CA  C    sing N N 107 
GLU CA  CB   sing N N 108 
GLU CA  HA   sing N N 109 
GLU C   O    doub N N 110 
GLU C   OXT  sing N N 111 
GLU CB  CG   sing N N 112 
GLU CB  HB2  sing N N 113 
GLU CB  HB3  sing N N 114 
GLU CG  CD   sing N N 115 
GLU CG  HG2  sing N N 116 
GLU CG  HG3  sing N N 117 
GLU CD  OE1  doub N N 118 
GLU CD  OE2  sing N N 119 
GLU OE2 HE2  sing N N 120 
GLU OXT HXT  sing N N 121 
GLY N   CA   sing N N 122 
GLY N   H    sing N N 123 
GLY N   H2   sing N N 124 
GLY CA  C    sing N N 125 
GLY CA  HA2  sing N N 126 
GLY CA  HA3  sing N N 127 
GLY C   O    doub N N 128 
GLY C   OXT  sing N N 129 
GLY OXT HXT  sing N N 130 
HIS N   CA   sing N N 131 
HIS N   H    sing N N 132 
HIS N   H2   sing N N 133 
HIS CA  C    sing N N 134 
HIS CA  CB   sing N N 135 
HIS CA  HA   sing N N 136 
HIS C   O    doub N N 137 
HIS C   OXT  sing N N 138 
HIS CB  CG   sing N N 139 
HIS CB  HB2  sing N N 140 
HIS CB  HB3  sing N N 141 
HIS CG  ND1  sing Y N 142 
HIS CG  CD2  doub Y N 143 
HIS ND1 CE1  doub Y N 144 
HIS ND1 HD1  sing N N 145 
HIS CD2 NE2  sing Y N 146 
HIS CD2 HD2  sing N N 147 
HIS CE1 NE2  sing Y N 148 
HIS CE1 HE1  sing N N 149 
HIS NE2 HE2  sing N N 150 
HIS OXT HXT  sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
SER N   CA   sing N N 260 
SER N   H    sing N N 261 
SER N   H2   sing N N 262 
SER CA  C    sing N N 263 
SER CA  CB   sing N N 264 
SER CA  HA   sing N N 265 
SER C   O    doub N N 266 
SER C   OXT  sing N N 267 
SER CB  OG   sing N N 268 
SER CB  HB2  sing N N 269 
SER CB  HB3  sing N N 270 
SER OG  HG   sing N N 271 
SER OXT HXT  sing N N 272 
TYR N   CA   sing N N 273 
TYR N   H    sing N N 274 
TYR N   H2   sing N N 275 
TYR CA  C    sing N N 276 
TYR CA  CB   sing N N 277 
TYR CA  HA   sing N N 278 
TYR C   O    doub N N 279 
TYR C   OXT  sing N N 280 
TYR CB  CG   sing N N 281 
TYR CB  HB2  sing N N 282 
TYR CB  HB3  sing N N 283 
TYR CG  CD1  doub Y N 284 
TYR CG  CD2  sing Y N 285 
TYR CD1 CE1  sing Y N 286 
TYR CD1 HD1  sing N N 287 
TYR CD2 CE2  doub Y N 288 
TYR CD2 HD2  sing N N 289 
TYR CE1 CZ   doub Y N 290 
TYR CE1 HE1  sing N N 291 
TYR CE2 CZ   sing Y N 292 
TYR CE2 HE2  sing N N 293 
TYR CZ  OH   sing N N 294 
TYR OH  HH   sing N N 295 
TYR OXT HXT  sing N N 296 
VAL N   CA   sing N N 297 
VAL N   H    sing N N 298 
VAL N   H2   sing N N 299 
VAL CA  C    sing N N 300 
VAL CA  CB   sing N N 301 
VAL CA  HA   sing N N 302 
VAL C   O    doub N N 303 
VAL C   OXT  sing N N 304 
VAL CB  CG1  sing N N 305 
VAL CB  CG2  sing N N 306 
VAL CB  HB   sing N N 307 
VAL CG1 HG11 sing N N 308 
VAL CG1 HG12 sing N N 309 
VAL CG1 HG13 sing N N 310 
VAL CG2 HG21 sing N N 311 
VAL CG2 HG22 sing N N 312 
VAL CG2 HG23 sing N N 313 
VAL OXT HXT  sing N N 314 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JB0 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-03-26 
_em_admin.title              'Cryo-EM structure of the class II amyloid-beta 42 fibril containing a D-Asp at position 23' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                brain 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          32630 
_em_entity_assembly_recombinant.organism             'synthetic construct' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_entity_assembly_synthetic.cell                 ? 
_em_entity_assembly_synthetic.cellular_location    ? 
_em_entity_assembly_synthetic.entity_assembly_id   1 
_em_entity_assembly_synthetic.id                   1 
_em_entity_assembly_synthetic.ncbi_tax_id          32630 
_em_entity_assembly_synthetic.organ                ? 
_em_entity_assembly_synthetic.organelle            ? 
_em_entity_assembly_synthetic.organism             'synthetic construct' 
_em_entity_assembly_synthetic.strain               ? 
_em_entity_assembly_synthetic.tissue               ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   178.45 
_em_helical_entity.axial_rise_per_subunit         2.37 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21_5207: 
'IMAGE ACQUISITION'             ? 2  1 ? 1 ?      ?          
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?          
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?          
CLASSIFICATION                  ? 5  1 1 1 ?      ?          
MASKING                         ? 6  1 1 1 ?      ?          
RECONSTRUCTION                  ? 7  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?          
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?          
'CTF CORRECTION'                ? 10 1 1 1 ?      ?          
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?          
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?          
'MODEL FITTING'                 ? 13 1 1 1 ?      ?          
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?          
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?          
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?          
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?          
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?          
OTHER                           ? 19 1 1 1 ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Academia Sinica (Taiwan)' 
_pdbx_audit_support.country                Taiwan 
_pdbx_audit_support.grant_number           110-2113-M-001-050-MY3 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JB0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 9  ? 77.593  113.495 110.049 1.00 75.58  ? 9  GLY CC N   1 
ATOM   2    C CA  . GLY A 1 9  ? 78.434  112.796 111.002 1.00 77.59  ? 9  GLY CC CA  1 
ATOM   3    C C   . GLY A 1 9  ? 79.655  112.164 110.367 1.00 77.76  ? 9  GLY CC C   1 
ATOM   4    O O   . GLY A 1 9  ? 79.561  111.534 109.315 1.00 78.65  ? 9  GLY CC O   1 
ATOM   5    N N   . TYR A 1 10 ? 80.807  112.330 111.009 1.00 74.83  ? 10 TYR CC N   1 
ATOM   6    C CA  . TYR A 1 10 ? 82.070  111.798 110.518 1.00 70.87  ? 10 TYR CC CA  1 
ATOM   7    C C   . TYR A 1 10 ? 82.461  110.586 111.349 1.00 65.85  ? 10 TYR CC C   1 
ATOM   8    O O   . TYR A 1 10 ? 82.399  110.628 112.582 1.00 68.66  ? 10 TYR CC O   1 
ATOM   9    C CB  . TYR A 1 10 ? 83.179  112.851 110.580 1.00 71.13  ? 10 TYR CC CB  1 
ATOM   10   C CG  . TYR A 1 10 ? 82.914  114.100 109.767 1.00 81.03  ? 10 TYR CC CG  1 
ATOM   11   C CD1 . TYR A 1 10 ? 81.951  114.117 108.768 1.00 83.11  ? 10 TYR CC CD1 1 
ATOM   12   C CD2 . TYR A 1 10 ? 83.639  115.260 109.995 1.00 80.21  ? 10 TYR CC CD2 1 
ATOM   13   C CE1 . TYR A 1 10 ? 81.710  115.258 108.029 1.00 84.09  ? 10 TYR CC CE1 1 
ATOM   14   C CE2 . TYR A 1 10 ? 83.407  116.404 109.260 1.00 87.12  ? 10 TYR CC CE2 1 
ATOM   15   C CZ  . TYR A 1 10 ? 82.443  116.397 108.277 1.00 91.17  ? 10 TYR CC CZ  1 
ATOM   16   O OH  . TYR A 1 10 ? 82.209  117.535 107.541 1.00 91.09  ? 10 TYR CC OH  1 
ATOM   17   N N   . GLU A 1 11 ? 82.859  109.511 110.677 1.00 61.80  ? 11 GLU CC N   1 
ATOM   18   C CA  . GLU A 1 11 ? 83.330  108.295 111.333 1.00 57.88  ? 11 GLU CC CA  1 
ATOM   19   C C   . GLU A 1 11 ? 84.709  107.971 110.773 1.00 52.72  ? 11 GLU CC C   1 
ATOM   20   O O   . GLU A 1 11 ? 84.827  107.371 109.701 1.00 58.89  ? 11 GLU CC O   1 
ATOM   21   C CB  . GLU A 1 11 ? 82.358  107.141 111.124 1.00 61.88  ? 11 GLU CC CB  1 
ATOM   22   C CG  . GLU A 1 11 ? 82.476  106.047 112.168 1.00 65.71  ? 11 GLU CC CG  1 
ATOM   23   C CD  . GLU A 1 11 ? 81.684  104.809 111.806 1.00 76.41  ? 11 GLU CC CD  1 
ATOM   24   O OE1 . GLU A 1 11 ? 80.473  104.936 111.531 1.00 81.59  ? 11 GLU CC OE1 1 
ATOM   25   O OE2 . GLU A 1 11 ? 82.272  103.708 111.800 1.00 75.54  ? 11 GLU CC OE2 1 
ATOM   26   N N   . VAL A 1 12 ? 85.748  108.367 111.499 1.00 47.56  ? 12 VAL CC N   1 
ATOM   27   C CA  . VAL A 1 12 ? 87.132  108.169 111.089 1.00 41.82  ? 12 VAL CC CA  1 
ATOM   28   C C   . VAL A 1 12 ? 87.751  107.147 112.030 1.00 43.59  ? 12 VAL CC C   1 
ATOM   29   O O   . VAL A 1 12 ? 87.718  107.326 113.252 1.00 54.65  ? 12 VAL CC O   1 
ATOM   30   C CB  . VAL A 1 12 ? 87.917  109.488 111.114 1.00 38.02  ? 12 VAL CC CB  1 
ATOM   31   C CG1 . VAL A 1 12 ? 89.303  109.296 110.543 1.00 36.81  ? 12 VAL CC CG1 1 
ATOM   32   C CG2 . VAL A 1 12 ? 87.165  110.561 110.354 1.00 37.82  ? 12 VAL CC CG2 1 
ATOM   33   N N   . HIS A 1 13 ? 88.310  106.075 111.474 1.00 39.40  ? 13 HIS CC N   1 
ATOM   34   C CA  . HIS A 1 13 ? 88.942  105.072 112.318 1.00 42.52  ? 13 HIS CC CA  1 
ATOM   35   C C   . HIS A 1 13 ? 90.034  104.342 111.551 1.00 39.69  ? 13 HIS CC C   1 
ATOM   36   O O   . HIS A 1 13 ? 90.122  104.424 110.328 1.00 38.87  ? 13 HIS CC O   1 
ATOM   37   C CB  . HIS A 1 13 ? 87.929  104.068 112.885 1.00 45.91  ? 13 HIS CC CB  1 
ATOM   38   C CG  . HIS A 1 13 ? 86.915  103.584 111.896 1.00 46.41  ? 13 HIS CC CG  1 
ATOM   39   N ND1 . HIS A 1 13 ? 86.826  102.264 111.514 1.00 43.92  ? 13 HIS CC ND1 1 
ATOM   40   C CD2 . HIS A 1 13 ? 85.924  104.233 111.242 1.00 49.27  ? 13 HIS CC CD2 1 
ATOM   41   C CE1 . HIS A 1 13 ? 85.837  102.124 110.651 1.00 48.42  ? 13 HIS CC CE1 1 
ATOM   42   N NE2 . HIS A 1 13 ? 85.274  103.304 110.468 1.00 50.84  ? 13 HIS CC NE2 1 
ATOM   43   N N   . HIS A 1 14 ? 90.887  103.650 112.305 1.00 39.43  ? 14 HIS CC N   1 
ATOM   44   C CA  . HIS A 1 14 ? 91.937  102.788 111.763 1.00 36.41  ? 14 HIS CC CA  1 
ATOM   45   C C   . HIS A 1 14 ? 92.881  103.559 110.839 1.00 34.91  ? 14 HIS CC C   1 
ATOM   46   O O   . HIS A 1 14 ? 92.982  103.292 109.646 1.00 41.49  ? 14 HIS CC O   1 
ATOM   47   C CB  . HIS A 1 14 ? 91.332  101.575 111.055 1.00 37.87  ? 14 HIS CC CB  1 
ATOM   48   C CG  . HIS A 1 14 ? 90.636  100.632 111.982 1.00 43.65  ? 14 HIS CC CG  1 
ATOM   49   N ND1 . HIS A 1 14 ? 89.294  100.735 112.278 1.00 45.90  ? 14 HIS CC ND1 1 
ATOM   50   C CD2 . HIS A 1 14 ? 91.100  99.581  112.697 1.00 47.98  ? 14 HIS CC CD2 1 
ATOM   51   C CE1 . HIS A 1 14 ? 88.959  99.780  113.127 1.00 53.85  ? 14 HIS CC CE1 1 
ATOM   52   N NE2 . HIS A 1 14 ? 90.037  99.066  113.397 1.00 57.15  ? 14 HIS CC NE2 1 
ATOM   53   N N   . GLN A 1 15 ? 93.585  104.523 111.421 1.00 31.09  ? 15 GLN CC N   1 
ATOM   54   C CA  . GLN A 1 15 ? 94.569  105.317 110.700 1.00 25.82  ? 15 GLN CC CA  1 
ATOM   55   C C   . GLN A 1 15 ? 95.945  105.085 111.299 1.00 27.11  ? 15 GLN CC C   1 
ATOM   56   O O   . GLN A 1 15 ? 96.113  105.149 112.520 1.00 36.68  ? 15 GLN CC O   1 
ATOM   57   C CB  . GLN A 1 15 ? 94.221  106.803 110.750 1.00 26.86  ? 15 GLN CC CB  1 
ATOM   58   C CG  . GLN A 1 15 ? 93.477  107.294 109.535 1.00 36.02  ? 15 GLN CC CG  1 
ATOM   59   C CD  . GLN A 1 15 ? 91.985  107.181 109.701 1.00 36.75  ? 15 GLN CC CD  1 
ATOM   60   O OE1 . GLN A 1 15 ? 91.490  106.977 110.805 1.00 32.60  ? 15 GLN CC OE1 1 
ATOM   61   N NE2 . GLN A 1 15 ? 91.256  107.308 108.602 1.00 36.88  ? 15 GLN CC NE2 1 
ATOM   62   N N   . LYS A 1 16 ? 96.922  104.813 110.443 1.00 25.46  ? 16 LYS CC N   1 
ATOM   63   C CA  . LYS A 1 16 ? 98.322  104.708 110.842 1.00 23.75  ? 16 LYS CC CA  1 
ATOM   64   C C   . LYS A 1 16 ? 99.066  105.847 110.159 1.00 27.50  ? 16 LYS CC C   1 
ATOM   65   O O   . LYS A 1 16 ? 99.387  105.762 108.971 1.00 37.91  ? 16 LYS CC O   1 
ATOM   66   C CB  . LYS A 1 16 ? 98.908  103.354 110.468 1.00 23.54  ? 16 LYS CC CB  1 
ATOM   67   C CG  . LYS A 1 16 ? 98.154  102.184 111.044 1.00 20.89  ? 16 LYS CC CG  1 
ATOM   68   C CD  . LYS A 1 16 ? 98.888  100.894 110.780 1.00 22.06  ? 16 LYS CC CD  1 
ATOM   69   C CE  . LYS A 1 16 ? 98.170  99.725  111.409 1.00 22.83  ? 16 LYS CC CE  1 
ATOM   70   N NZ  . LYS A 1 16 ? 99.041  98.527  111.436 1.00 28.31  ? 16 LYS CC NZ  1 
ATOM   71   N N   . LEU A 1 17 ? 99.341  106.909 110.906 1.00 23.96  ? 17 LEU CC N   1 
ATOM   72   C CA  . LEU A 1 17 ? 99.922  108.125 110.360 1.00 25.08  ? 17 LEU CC CA  1 
ATOM   73   C C   . LEU A 1 17 ? 101.311 108.336 110.938 1.00 25.06  ? 17 LEU CC C   1 
ATOM   74   O O   . LEU A 1 17 ? 101.498 108.258 112.155 1.00 32.20  ? 17 LEU CC O   1 
ATOM   75   C CB  . LEU A 1 17 ? 99.034  109.332 110.663 1.00 25.85  ? 17 LEU CC CB  1 
ATOM   76   C CG  . LEU A 1 17 ? 99.296  110.600 109.856 1.00 28.96  ? 17 LEU CC CG  1 
ATOM   77   C CD1 . LEU A 1 17 ? 97.983  111.205 109.413 1.00 37.70  ? 17 LEU CC CD1 1 
ATOM   78   C CD2 . LEU A 1 17 ? 100.099 111.600 110.665 1.00 27.85  ? 17 LEU CC CD2 1 
ATOM   79   N N   . VAL A 1 18 ? 102.280 108.594 110.067 1.00 24.89  ? 18 VAL CC N   1 
ATOM   80   C CA  . VAL A 1 18 ? 103.624 108.989 110.467 1.00 26.58  ? 18 VAL CC CA  1 
ATOM   81   C C   . VAL A 1 18 ? 103.918 110.340 109.838 1.00 29.85  ? 18 VAL CC C   1 
ATOM   82   O O   . VAL A 1 18 ? 103.779 110.507 108.622 1.00 35.03  ? 18 VAL CC O   1 
ATOM   83   C CB  . VAL A 1 18 ? 104.679 107.949 110.053 1.00 25.75  ? 18 VAL CC CB  1 
ATOM   84   C CG1 . VAL A 1 18 ? 105.984 108.229 110.760 1.00 24.22  ? 18 VAL CC CG1 1 
ATOM   85   C CG2 . VAL A 1 18 ? 104.198 106.552 110.375 1.00 24.63  ? 18 VAL CC CG2 1 
ATOM   86   N N   . PHE A 1 19 ? 104.320 111.300 110.664 1.00 30.43  ? 19 PHE CC N   1 
ATOM   87   C CA  . PHE A 1 19 ? 104.523 112.677 110.238 1.00 32.79  ? 19 PHE CC CA  1 
ATOM   88   C C   . PHE A 1 19 ? 105.950 113.090 110.559 1.00 36.31  ? 19 PHE CC C   1 
ATOM   89   O O   . PHE A 1 19 ? 106.336 113.131 111.730 1.00 43.04  ? 19 PHE CC O   1 
ATOM   90   C CB  . PHE A 1 19 ? 103.522 113.604 110.929 1.00 36.08  ? 19 PHE CC CB  1 
ATOM   91   C CG  . PHE A 1 19 ? 103.369 114.940 110.268 1.00 38.70  ? 19 PHE CC CG  1 
ATOM   92   C CD1 . PHE A 1 19 ? 104.342 115.913 110.407 1.00 38.82  ? 19 PHE CC CD1 1 
ATOM   93   C CD2 . PHE A 1 19 ? 102.245 115.230 109.522 1.00 41.78  ? 19 PHE CC CD2 1 
ATOM   94   C CE1 . PHE A 1 19 ? 104.200 117.143 109.805 1.00 39.93  ? 19 PHE CC CE1 1 
ATOM   95   C CE2 . PHE A 1 19 ? 102.098 116.459 108.919 1.00 44.10  ? 19 PHE CC CE2 1 
ATOM   96   C CZ  . PHE A 1 19 ? 103.077 117.416 109.061 1.00 44.51  ? 19 PHE CC CZ  1 
ATOM   97   N N   . PHE A 1 20 ? 106.724 113.397 109.526 1.00 35.86  ? 20 PHE CC N   1 
ATOM   98   C CA  . PHE A 1 20 ? 108.074 113.921 109.675 1.00 37.59  ? 20 PHE CC CA  1 
ATOM   99   C C   . PHE A 1 20 ? 108.069 115.399 109.320 1.00 45.25  ? 20 PHE CC C   1 
ATOM   100  O O   . PHE A 1 20 ? 107.526 115.787 108.282 1.00 55.23  ? 20 PHE CC O   1 
ATOM   101  C CB  . PHE A 1 20 ? 109.066 113.181 108.778 1.00 39.09  ? 20 PHE CC CB  1 
ATOM   102  C CG  . PHE A 1 20 ? 109.294 111.753 109.163 1.00 38.58  ? 20 PHE CC CG  1 
ATOM   103  C CD1 . PHE A 1 20 ? 108.507 110.748 108.636 1.00 36.65  ? 20 PHE CC CD1 1 
ATOM   104  C CD2 . PHE A 1 20 ? 110.310 111.411 110.033 1.00 35.18  ? 20 PHE CC CD2 1 
ATOM   105  C CE1 . PHE A 1 20 ? 108.723 109.434 108.979 1.00 33.87  ? 20 PHE CC CE1 1 
ATOM   106  C CE2 . PHE A 1 20 ? 110.528 110.097 110.379 1.00 34.77  ? 20 PHE CC CE2 1 
ATOM   107  C CZ  . PHE A 1 20 ? 109.733 109.108 109.852 1.00 31.87  ? 20 PHE CC CZ  1 
ATOM   108  N N   . ALA A 1 21 ? 108.666 116.216 110.177 1.00 46.71  ? 21 ALA CC N   1 
ATOM   109  C CA  . ALA A 1 21 ? 108.800 117.642 109.925 1.00 51.62  ? 21 ALA CC CA  1 
ATOM   110  C C   . ALA A 1 21 ? 110.230 118.067 110.210 1.00 59.08  ? 21 ALA CC C   1 
ATOM   111  O O   . ALA A 1 21 ? 110.828 117.637 111.199 1.00 64.50  ? 21 ALA CC O   1 
ATOM   112  C CB  . ALA A 1 21 ? 107.825 118.456 110.778 1.00 47.68  ? 21 ALA CC CB  1 
ATOM   113  N N   . GLU A 1 22 ? 110.776 118.904 109.338 1.00 62.23  ? 22 GLU CC N   1 
ATOM   114  C CA  . GLU A 1 22 ? 112.128 119.410 109.519 1.00 69.45  ? 22 GLU CC CA  1 
ATOM   115  C C   . GLU A 1 22 ? 112.173 120.915 109.315 1.00 74.34  ? 22 GLU CC C   1 
ATOM   116  O O   . GLU A 1 22 ? 111.404 121.466 108.531 1.00 78.12  ? 22 GLU CC O   1 
ATOM   117  C CB  . GLU A 1 22 ? 113.097 118.722 108.561 1.00 72.05  ? 22 GLU CC CB  1 
ATOM   118  C CG  . GLU A 1 22 ? 113.569 117.368 109.039 1.00 71.84  ? 22 GLU CC CG  1 
ATOM   119  C CD  . GLU A 1 22 ? 115.020 117.380 109.469 1.00 75.14  ? 22 GLU CC CD  1 
ATOM   120  O OE1 . GLU A 1 22 ? 115.596 118.482 109.586 1.00 75.71  ? 22 GLU CC OE1 1 
ATOM   121  O OE2 . GLU A 1 22 ? 115.587 116.289 109.690 1.00 74.25  ? 22 GLU CC OE2 1 
HETATM 122  N N   . DAS A 1 23 ? 113.080 121.574 110.023 1.00 72.71  ? 23 DAS CC N   1 
HETATM 123  C CA  . DAS A 1 23 ? 113.193 123.021 109.953 1.00 76.75  ? 23 DAS CC CA  1 
HETATM 124  C C   . DAS A 1 23 ? 111.989 123.655 110.635 1.00 76.02  ? 23 DAS CC C   1 
HETATM 125  O O   . DAS A 1 23 ? 111.986 123.842 111.851 1.00 76.84  ? 23 DAS CC O   1 
HETATM 126  C CB  . DAS A 1 23 ? 114.487 123.485 110.622 1.00 83.90  ? 23 DAS CC CB  1 
HETATM 127  C CG  . DAS A 1 23 ? 114.786 124.948 110.364 1.00 88.14  ? 23 DAS CC CG  1 
HETATM 128  O OD1 . DAS A 1 23 ? 114.075 125.571 109.549 1.00 87.21  ? 23 DAS CC OD1 1 
HETATM 129  O OD2 . DAS A 1 23 ? 115.736 125.478 110.979 1.00 86.54  ? 23 DAS CC OD2 1 
ATOM   130  N N   . VAL A 1 24 ? 110.968 123.968 109.841 1.00 73.27  ? 24 VAL CC N   1 
ATOM   131  C CA  . VAL A 1 24 ? 109.735 124.582 110.328 1.00 69.90  ? 24 VAL CC CA  1 
ATOM   132  C C   . VAL A 1 24 ? 110.032 125.815 111.176 1.00 67.77  ? 24 VAL CC C   1 
ATOM   133  O O   . VAL A 1 24 ? 109.834 125.810 112.387 1.00 70.39  ? 24 VAL CC O   1 
ATOM   134  C CB  . VAL A 1 24 ? 108.884 123.572 111.116 1.00 64.79  ? 24 VAL CC CB  1 
ATOM   135  C CG1 . VAL A 1 24 ? 107.483 124.110 111.319 1.00 56.42  ? 24 VAL CC CG1 1 
ATOM   136  C CG2 . VAL A 1 24 ? 108.836 122.241 110.392 1.00 58.59  ? 24 VAL CC CG2 1 
ATOM   137  N N   . GLY A 1 25 ? 110.514 126.875 110.532 1.00 65.16  ? 25 GLY CC N   1 
ATOM   138  C CA  . GLY A 1 25 ? 110.882 128.094 111.226 1.00 63.72  ? 25 GLY CC CA  1 
ATOM   139  C C   . GLY A 1 25 ? 109.804 129.153 111.086 1.00 65.69  ? 25 GLY CC C   1 
ATOM   140  O O   . GLY A 1 25 ? 109.268 129.370 109.998 1.00 67.63  ? 25 GLY CC O   1 
ATOM   141  N N   . SER A 1 26 ? 109.497 129.806 112.207 1.00 66.41  ? 26 SER CC N   1 
ATOM   142  C CA  . SER A 1 26 ? 108.554 130.924 112.246 1.00 66.74  ? 26 SER CC CA  1 
ATOM   143  C C   . SER A 1 26 ? 107.198 130.535 111.662 1.00 62.57  ? 26 SER CC C   1 
ATOM   144  O O   . SER A 1 26 ? 106.598 131.270 110.876 1.00 59.58  ? 26 SER CC O   1 
ATOM   145  C CB  . SER A 1 26 ? 109.131 132.146 111.528 1.00 65.12  ? 26 SER CC CB  1 
ATOM   146  O OG  . SER A 1 26 ? 110.532 132.231 111.716 1.00 62.29  ? 26 SER CC OG  1 
ATOM   147  N N   . ASN A 1 27 ? 106.712 129.362 112.057 1.00 58.74  ? 27 ASN CC N   1 
ATOM   148  C CA  . ASN A 1 27 ? 105.406 128.904 111.607 1.00 53.96  ? 27 ASN CC CA  1 
ATOM   149  C C   . ASN A 1 27 ? 104.311 129.722 112.279 1.00 54.07  ? 27 ASN CC C   1 
ATOM   150  O O   . ASN A 1 27 ? 104.217 129.752 113.510 1.00 61.28  ? 27 ASN CC O   1 
ATOM   151  C CB  . ASN A 1 27 ? 105.229 127.420 111.914 1.00 53.66  ? 27 ASN CC CB  1 
ATOM   152  C CG  . ASN A 1 27 ? 103.773 127.004 111.957 1.00 48.69  ? 27 ASN CC CG  1 
ATOM   153  O OD1 . ASN A 1 27 ? 103.042 127.164 110.983 1.00 46.96  ? 27 ASN CC OD1 1 
ATOM   154  N ND2 . ASN A 1 27 ? 103.345 126.468 113.091 1.00 48.76  ? 27 ASN CC ND2 1 
ATOM   155  N N   . LYS A 1 28 ? 103.489 130.389 111.474 1.00 49.39  ? 28 LYS CC N   1 
ATOM   156  C CA  . LYS A 1 28 ? 102.353 131.146 111.975 1.00 50.70  ? 28 LYS CC CA  1 
ATOM   157  C C   . LYS A 1 28 ? 101.021 130.482 111.668 1.00 50.43  ? 28 LYS CC C   1 
ATOM   158  O O   . LYS A 1 28 ? 99.974  131.027 112.030 1.00 47.12  ? 28 LYS CC O   1 
ATOM   159  C CB  . LYS A 1 28 ? 102.368 132.566 111.401 1.00 51.94  ? 28 LYS CC CB  1 
ATOM   160  C CG  . LYS A 1 28 ? 103.681 133.295 111.605 1.00 54.88  ? 28 LYS CC CG  1 
ATOM   161  C CD  . LYS A 1 28 ? 103.479 134.799 111.619 1.00 56.29  ? 28 LYS CC CD  1 
ATOM   162  C CE  . LYS A 1 28 ? 104.808 135.531 111.672 1.00 61.55  ? 28 LYS CC CE  1 
ATOM   163  N NZ  . LYS A 1 28 ? 105.962 134.591 111.668 1.00 55.99  ? 28 LYS CC NZ  1 
ATOM   164  N N   . GLY A 1 29 ? 101.030 129.323 111.010 1.00 54.52  ? 29 GLY CC N   1 
ATOM   165  C CA  . GLY A 1 29 ? 99.833  128.597 110.689 1.00 50.66  ? 29 GLY CC CA  1 
ATOM   166  C C   . GLY A 1 29 ? 99.688  127.327 111.500 1.00 49.00  ? 29 GLY CC C   1 
ATOM   167  O O   . GLY A 1 29 ? 100.338 127.135 112.535 1.00 48.69  ? 29 GLY CC O   1 
ATOM   168  N N   . ALA A 1 30 ? 98.826  126.440 111.016 1.00 48.30  ? 30 ALA CC N   1 
ATOM   169  C CA  . ALA A 1 30 ? 98.533  125.179 111.682 1.00 41.05  ? 30 ALA CC CA  1 
ATOM   170  C C   . ALA A 1 30 ? 99.229  124.047 110.942 1.00 40.65  ? 30 ALA CC C   1 
ATOM   171  O O   . ALA A 1 30 ? 99.040  123.883 109.733 1.00 43.98  ? 30 ALA CC O   1 
ATOM   172  C CB  . ALA A 1 30 ? 97.026  124.932 111.742 1.00 35.72  ? 30 ALA CC CB  1 
ATOM   173  N N   . ILE A 1 31 ? 100.029 123.272 111.666 1.00 38.51  ? 31 ILE CC N   1 
ATOM   174  C CA  . ILE A 1 31 ? 100.671 122.075 111.138 1.00 37.05  ? 31 ILE CC CA  1 
ATOM   175  C C   . ILE A 1 31 ? 100.092 120.891 111.895 1.00 40.18  ? 31 ILE CC C   1 
ATOM   176  O O   . ILE A 1 31 ? 100.418 120.673 113.068 1.00 49.66  ? 31 ILE CC O   1 
ATOM   177  C CB  . ILE A 1 31 ? 102.196 122.135 111.276 1.00 33.50  ? 31 ILE CC CB  1 
ATOM   178  C CG1 . ILE A 1 31 ? 102.742 123.332 110.504 1.00 38.10  ? 31 ILE CC CG1 1 
ATOM   179  C CG2 . ILE A 1 31 ? 102.823 120.842 110.788 1.00 30.82  ? 31 ILE CC CG2 1 
ATOM   180  C CD1 . ILE A 1 31 ? 104.222 123.285 110.286 1.00 42.08  ? 31 ILE CC CD1 1 
ATOM   181  N N   . ILE A 1 32 ? 99.235  120.123 111.231 1.00 37.80  ? 32 ILE CC N   1 
ATOM   182  C CA  . ILE A 1 32 ? 98.476  119.057 111.869 1.00 42.84  ? 32 ILE CC CA  1 
ATOM   183  C C   . ILE A 1 32 ? 98.775  117.744 111.163 1.00 42.30  ? 32 ILE CC C   1 
ATOM   184  O O   . ILE A 1 32 ? 98.849  117.693 109.932 1.00 45.16  ? 32 ILE CC O   1 
ATOM   185  C CB  . ILE A 1 32 ? 96.962  119.352 111.854 1.00 44.85  ? 32 ILE CC CB  1 
ATOM   186  C CG1 . ILE A 1 32 ? 96.693  120.771 112.354 1.00 42.64  ? 32 ILE CC CG1 1 
ATOM   187  C CG2 . ILE A 1 32 ? 96.220  118.351 112.711 1.00 48.55  ? 32 ILE CC CG2 1 
ATOM   188  C CD1 . ILE A 1 32 ? 95.613  121.492 111.589 1.00 40.67  ? 32 ILE CC CD1 1 
ATOM   189  N N   . GLY A 1 33 ? 98.962  116.686 111.945 1.00 44.70  ? 33 GLY CC N   1 
ATOM   190  C CA  . GLY A 1 33 ? 99.146  115.365 111.381 1.00 40.70  ? 33 GLY CC CA  1 
ATOM   191  C C   . GLY A 1 33 ? 97.847  114.789 110.864 1.00 40.23  ? 33 GLY CC C   1 
ATOM   192  O O   . GLY A 1 33 ? 97.719  114.495 109.674 1.00 43.73  ? 33 GLY CC O   1 
ATOM   193  N N   . LEU A 1 34 ? 96.873  114.618 111.752 1.00 41.37  ? 34 LEU CC N   1 
ATOM   194  C CA  . LEU A 1 34 ? 95.536  114.173 111.382 1.00 41.56  ? 34 LEU CC CA  1 
ATOM   195  C C   . LEU A 1 34 ? 94.537  115.163 111.955 1.00 43.59  ? 34 LEU CC C   1 
ATOM   196  O O   . LEU A 1 34 ? 94.521  115.395 113.167 1.00 52.62  ? 34 LEU CC O   1 
ATOM   197  C CB  . LEU A 1 34 ? 95.252  112.763 111.903 1.00 42.98  ? 34 LEU CC CB  1 
ATOM   198  C CG  . LEU A 1 34 ? 94.056  112.035 111.290 1.00 39.98  ? 34 LEU CC CG  1 
ATOM   199  C CD1 . LEU A 1 34 ? 94.448  110.621 110.907 1.00 33.09  ? 34 LEU CC CD1 1 
ATOM   200  C CD2 . LEU A 1 34 ? 92.868  112.029 112.231 1.00 40.03  ? 34 LEU CC CD2 1 
ATOM   201  N N   . MET A 1 35 ? 93.709  115.743 111.095 1.00 38.84  ? 35 MET CC N   1 
ATOM   202  C CA  . MET A 1 35 ? 92.728  116.735 111.504 1.00 44.10  ? 35 MET CC CA  1 
ATOM   203  C C   . MET A 1 35 ? 91.346  116.292 111.055 1.00 48.26  ? 35 MET CC C   1 
ATOM   204  O O   . MET A 1 35 ? 91.149  115.960 109.883 1.00 57.64  ? 35 MET CC O   1 
ATOM   205  C CB  . MET A 1 35 ? 93.059  118.107 110.918 1.00 46.59  ? 35 MET CC CB  1 
ATOM   206  C CG  . MET A 1 35 ? 91.890  119.066 110.912 1.00 51.67  ? 35 MET CC CG  1 
ATOM   207  S SD  . MET A 1 35 ? 91.853  120.145 112.345 1.00 73.51  ? 35 MET CC SD  1 
ATOM   208  C CE  . MET A 1 35 ? 90.182  120.771 112.251 1.00 71.03  ? 35 MET CC CE  1 
ATOM   209  N N   . VAL A 1 36 ? 90.398  116.281 111.985 1.00 48.97  ? 36 VAL CC N   1 
ATOM   210  C CA  . VAL A 1 36 ? 89.003  115.977 111.692 1.00 50.21  ? 36 VAL CC CA  1 
ATOM   211  C C   . VAL A 1 36 ? 88.168  117.154 112.172 1.00 56.88  ? 36 VAL CC C   1 
ATOM   212  O O   . VAL A 1 36 ? 88.275  117.563 113.333 1.00 64.00  ? 36 VAL CC O   1 
ATOM   213  C CB  . VAL A 1 36 ? 88.545  114.672 112.359 1.00 46.62  ? 36 VAL CC CB  1 
ATOM   214  C CG1 . VAL A 1 36 ? 87.071  114.433 112.088 1.00 48.09  ? 36 VAL CC CG1 1 
ATOM   215  C CG2 . VAL A 1 36 ? 89.378  113.505 111.863 1.00 41.47  ? 36 VAL CC CG2 1 
ATOM   216  N N   . GLY A 1 37 ? 87.341  117.695 111.284 1.00 56.15  ? 37 GLY CC N   1 
ATOM   217  C CA  . GLY A 1 37 ? 86.543  118.854 111.624 1.00 61.50  ? 37 GLY CC CA  1 
ATOM   218  C C   . GLY A 1 37 ? 86.563  119.920 110.552 1.00 74.49  ? 37 GLY CC C   1 
ATOM   219  O O   . GLY A 1 37 ? 86.119  119.683 109.426 1.00 81.43  ? 37 GLY CC O   1 
ATOM   220  N N   . GLY A 1 38 ? 87.065  121.099 110.886 1.00 77.39  ? 38 GLY CC N   1 
ATOM   221  C CA  . GLY A 1 38 ? 87.121  122.189 109.928 1.00 82.98  ? 38 GLY CC CA  1 
ATOM   222  C C   . GLY A 1 38 ? 88.275  123.114 110.226 1.00 87.96  ? 38 GLY CC C   1 
ATOM   223  O O   . GLY A 1 38 ? 88.559  123.431 111.386 1.00 86.27  ? 38 GLY CC O   1 
ATOM   224  N N   . VAL A 1 39 ? 88.942  123.558 109.165 1.00 90.26  ? 39 VAL CC N   1 
ATOM   225  C CA  . VAL A 1 39 ? 90.070  124.475 109.261 1.00 94.48  ? 39 VAL CC CA  1 
ATOM   226  C C   . VAL A 1 39 ? 89.709  125.753 108.522 1.00 97.76  ? 39 VAL CC C   1 
ATOM   227  O O   . VAL A 1 39 ? 89.381  125.716 107.330 1.00 93.80  ? 39 VAL CC O   1 
ATOM   228  C CB  . VAL A 1 39 ? 91.358  123.856 108.687 1.00 91.47  ? 39 VAL CC CB  1 
ATOM   229  C CG1 . VAL A 1 39 ? 92.399  124.932 108.438 1.00 90.96  ? 39 VAL CC CG1 1 
ATOM   230  C CG2 . VAL A 1 39 ? 91.900  122.800 109.631 1.00 86.64  ? 39 VAL CC CG2 1 
ATOM   231  N N   . VAL A 1 40 ? 89.764  126.878 109.228 1.00 101.84 ? 40 VAL CC N   1 
ATOM   232  C CA  . VAL A 1 40 ? 89.502  128.192 108.655 1.00 102.74 ? 40 VAL CC CA  1 
ATOM   233  C C   . VAL A 1 40 ? 90.759  129.030 108.828 1.00 105.52 ? 40 VAL CC C   1 
ATOM   234  O O   . VAL A 1 40 ? 91.247  129.202 109.951 1.00 105.13 ? 40 VAL CC O   1 
ATOM   235  C CB  . VAL A 1 40 ? 88.293  128.875 109.312 1.00 100.19 ? 40 VAL CC CB  1 
ATOM   236  C CG1 . VAL A 1 40 ? 88.017  130.212 108.647 1.00 98.42  ? 40 VAL CC CG1 1 
ATOM   237  C CG2 . VAL A 1 40 ? 87.071  127.976 109.235 1.00 97.85  ? 40 VAL CC CG2 1 
ATOM   238  N N   . ILE A 1 41 ? 91.280  129.549 107.721 1.00 108.51 ? 41 ILE CC N   1 
ATOM   239  C CA  . ILE A 1 41 ? 92.499  130.349 107.722 1.00 112.67 ? 41 ILE CC CA  1 
ATOM   240  C C   . ILE A 1 41 ? 92.138  131.785 107.375 1.00 116.23 ? 41 ILE CC C   1 
ATOM   241  O O   . ILE A 1 41 ? 91.482  132.041 106.358 1.00 115.97 ? 41 ILE CC O   1 
ATOM   242  C CB  . ILE A 1 41 ? 93.534  129.788 106.734 1.00 112.79 ? 41 ILE CC CB  1 
ATOM   243  C CG1 . ILE A 1 41 ? 93.735  128.291 106.969 1.00 107.76 ? 41 ILE CC CG1 1 
ATOM   244  C CG2 . ILE A 1 41 ? 94.853  130.529 106.869 1.00 110.95 ? 41 ILE CC CG2 1 
ATOM   245  C CD1 . ILE A 1 41 ? 94.611  127.631 105.934 1.00 104.16 ? 41 ILE CC CD1 1 
ATOM   246  N N   . ALA A 1 42 ? 92.563  132.720 108.217 1.00 118.92 ? 42 ALA CC N   1 
ATOM   247  C CA  . ALA A 1 42 ? 92.279  134.131 107.999 1.00 121.66 ? 42 ALA CC CA  1 
ATOM   248  C C   . ALA A 1 42 ? 93.446  134.997 108.463 1.00 127.02 ? 42 ALA CC C   1 
ATOM   249  O O   . ALA A 1 42 ? 94.337  134.531 109.173 1.00 129.60 ? 42 ALA CC O   1 
ATOM   250  C CB  . ALA A 1 42 ? 91.002  134.532 108.718 1.00 117.58 ? 42 ALA CC CB  1 
ATOM   251  O OXT . ALA A 1 42 ? 93.528  136.181 108.137 1.00 127.70 ? 42 ALA CC OXT 1 
ATOM   252  N N   . GLY B 1 9  ? 78.042  115.029 114.777 1.00 75.58  ? 9  GLY BB N   1 
ATOM   253  C CA  . GLY B 1 9  ? 78.844  114.286 115.730 1.00 77.59  ? 9  GLY BB CA  1 
ATOM   254  C C   . GLY B 1 9  ? 80.028  113.587 115.095 1.00 77.76  ? 9  GLY BB C   1 
ATOM   255  O O   . GLY B 1 9  ? 79.899  112.964 114.043 1.00 78.65  ? 9  GLY BB O   1 
ATOM   256  N N   . TYR B 1 10 ? 81.187  113.690 115.737 1.00 74.83  ? 10 TYR BB N   1 
ATOM   257  C CA  . TYR B 1 10 ? 82.420  113.090 115.246 1.00 70.87  ? 10 TYR BB CA  1 
ATOM   258  C C   . TYR B 1 10 ? 82.745  111.859 116.077 1.00 65.85  ? 10 TYR BB C   1 
ATOM   259  O O   . TYR B 1 10 ? 82.685  111.904 117.309 1.00 68.66  ? 10 TYR BB O   1 
ATOM   260  C CB  . TYR B 1 10 ? 83.584  114.082 115.306 1.00 71.13  ? 10 TYR BB CB  1 
ATOM   261  C CG  . TYR B 1 10 ? 83.388  115.343 114.495 1.00 81.03  ? 10 TYR BB CG  1 
ATOM   262  C CD1 . TYR B 1 10 ? 82.427  115.413 113.495 1.00 83.11  ? 10 TYR BB CD1 1 
ATOM   263  C CD2 . TYR B 1 10 ? 84.175  116.462 114.722 1.00 80.21  ? 10 TYR BB CD2 1 
ATOM   264  C CE1 . TYR B 1 10 ? 82.249  116.565 112.756 1.00 84.09  ? 10 TYR BB CE1 1 
ATOM   265  C CE2 . TYR B 1 10 ? 84.006  117.617 113.987 1.00 87.12  ? 10 TYR BB CE2 1 
ATOM   266  C CZ  . TYR B 1 10 ? 83.042  117.663 113.004 1.00 91.17  ? 10 TYR BB CZ  1 
ATOM   267  O OH  . TYR B 1 10 ? 82.870  118.811 112.268 1.00 91.09  ? 10 TYR BB OH  1 
ATOM   268  N N   . GLU B 1 11 ? 83.082  110.764 115.404 1.00 61.80  ? 11 GLU BB N   1 
ATOM   269  C CA  . GLU B 1 11 ? 83.487  109.524 116.060 1.00 57.88  ? 11 GLU BB CA  1 
ATOM   270  C C   . GLU B 1 11 ? 84.846  109.125 115.499 1.00 52.72  ? 11 GLU BB C   1 
ATOM   271  O O   . GLU B 1 11 ? 84.931  108.520 114.428 1.00 58.89  ? 11 GLU BB O   1 
ATOM   272  C CB  . GLU B 1 11 ? 82.453  108.424 115.851 1.00 61.88  ? 11 GLU BB CB  1 
ATOM   273  C CG  . GLU B 1 11 ? 82.512  107.326 116.894 1.00 65.71  ? 11 GLU BB CG  1 
ATOM   274  C CD  . GLU B 1 11 ? 81.654  106.133 116.533 1.00 76.41  ? 11 GLU BB CD  1 
ATOM   275  O OE1 . GLU B 1 11 ? 80.451  106.326 116.258 1.00 81.59  ? 11 GLU BB OE1 1 
ATOM   276  O OE2 . GLU B 1 11 ? 82.181  105.001 116.527 1.00 75.54  ? 11 GLU BB OE2 1 
ATOM   277  N N   . VAL B 1 12 ? 85.905  109.464 116.225 1.00 47.56  ? 12 VAL BB N   1 
ATOM   278  C CA  . VAL B 1 12 ? 87.276  109.190 115.815 1.00 41.82  ? 12 VAL BB CA  1 
ATOM   279  C C   . VAL B 1 12 ? 87.838  108.136 116.756 1.00 43.59  ? 12 VAL BB C   1 
ATOM   280  O O   . VAL B 1 12 ? 87.815  108.317 117.978 1.00 54.65  ? 12 VAL BB O   1 
ATOM   281  C CB  . VAL B 1 12 ? 88.132  110.465 115.840 1.00 38.02  ? 12 VAL BB CB  1 
ATOM   282  C CG1 . VAL B 1 12 ? 89.505  110.198 115.268 1.00 36.81  ? 12 VAL BB CG1 1 
ATOM   283  C CG2 . VAL B 1 12 ? 87.439  111.578 115.080 1.00 37.82  ? 12 VAL BB CG2 1 
ATOM   284  N N   . HIS B 1 13 ? 88.339  107.035 116.200 1.00 39.40  ? 13 HIS BB N   1 
ATOM   285  C CA  . HIS B 1 13 ? 88.915  105.999 117.043 1.00 42.52  ? 13 HIS BB CA  1 
ATOM   286  C C   . HIS B 1 13 ? 89.965  105.211 116.276 1.00 39.69  ? 13 HIS BB C   1 
ATOM   287  O O   . HIS B 1 13 ? 90.057  105.288 115.053 1.00 38.87  ? 13 HIS BB O   1 
ATOM   288  C CB  . HIS B 1 13 ? 87.849  105.052 117.611 1.00 45.91  ? 13 HIS BB CB  1 
ATOM   289  C CG  . HIS B 1 13 ? 86.810  104.625 116.622 1.00 46.41  ? 13 HIS BB CG  1 
ATOM   290  N ND1 . HIS B 1 13 ? 86.648  103.311 116.240 1.00 43.92  ? 13 HIS BB ND1 1 
ATOM   291  C CD2 . HIS B 1 13 ? 85.855  105.327 115.968 1.00 49.27  ? 13 HIS BB CD2 1 
ATOM   292  C CE1 . HIS B 1 13 ? 85.653  103.225 115.377 1.00 48.42  ? 13 HIS BB CE1 1 
ATOM   293  N NE2 . HIS B 1 13 ? 85.155  104.434 115.194 1.00 50.84  ? 13 HIS BB NE2 1 
ATOM   294  N N   . HIS B 1 14 ? 90.779  104.473 117.030 1.00 39.43  ? 14 HIS BB N   1 
ATOM   295  C CA  . HIS B 1 14 ? 91.781  103.555 116.488 1.00 36.41  ? 14 HIS BB CA  1 
ATOM   296  C C   . HIS B 1 14 ? 92.765  104.274 115.564 1.00 34.91  ? 14 HIS BB C   1 
ATOM   297  O O   . HIS B 1 14 ? 92.851  104.002 114.370 1.00 41.49  ? 14 HIS BB O   1 
ATOM   298  C CB  . HIS B 1 14 ? 91.110  102.378 115.780 1.00 37.87  ? 14 HIS BB CB  1 
ATOM   299  C CG  . HIS B 1 14 ? 90.364  101.473 116.707 1.00 43.65  ? 14 HIS BB CG  1 
ATOM   300  N ND1 . HIS B 1 14 ? 89.030  101.649 117.003 1.00 45.90  ? 14 HIS BB ND1 1 
ATOM   301  C CD2 . HIS B 1 14 ? 90.770  100.399 117.421 1.00 47.98  ? 14 HIS BB CD2 1 
ATOM   302  C CE1 . HIS B 1 14 ? 88.644  100.714 117.852 1.00 53.85  ? 14 HIS BB CE1 1 
ATOM   303  N NE2 . HIS B 1 14 ? 89.681  99.943  118.122 1.00 57.15  ? 14 HIS BB NE2 1 
ATOM   304  N N   . GLN B 1 15 ? 93.521  105.198 116.145 1.00 31.09  ? 15 GLN BB N   1 
ATOM   305  C CA  . GLN B 1 15 ? 94.546  105.938 115.424 1.00 25.82  ? 15 GLN BB CA  1 
ATOM   306  C C   . GLN B 1 15 ? 95.908  105.630 116.023 1.00 27.11  ? 15 GLN BB C   1 
ATOM   307  O O   . GLN B 1 15 ? 96.079  105.685 117.243 1.00 36.68  ? 15 GLN BB O   1 
ATOM   308  C CB  . GLN B 1 15 ? 94.280  107.440 115.474 1.00 26.86  ? 15 GLN BB CB  1 
ATOM   309  C CG  . GLN B 1 15 ? 93.563  107.971 114.260 1.00 36.02  ? 15 GLN BB CG  1 
ATOM   310  C CD  . GLN B 1 15 ? 92.068  107.940 114.425 1.00 36.75  ? 15 GLN BB CD  1 
ATOM   311  O OE1 . GLN B 1 15 ? 91.562  107.763 115.530 1.00 32.60  ? 15 GLN BB OE1 1 
ATOM   312  N NE2 . GLN B 1 15 ? 91.347  108.106 113.326 1.00 36.88  ? 15 GLN BB NE2 1 
ATOM   313  N N   . LYS B 1 16 ? 96.869  105.306 115.167 1.00 25.46  ? 16 LYS BB N   1 
ATOM   314  C CA  . LYS B 1 16 ? 98.261  105.124 115.565 1.00 23.75  ? 16 LYS BB CA  1 
ATOM   315  C C   . LYS B 1 16 ? 99.065  106.221 114.882 1.00 27.50  ? 16 LYS BB C   1 
ATOM   316  O O   . LYS B 1 16 ? 99.381  106.119 113.694 1.00 37.91  ? 16 LYS BB O   1 
ATOM   317  C CB  . LYS B 1 16 ? 98.772  103.741 115.191 1.00 23.54  ? 16 LYS BB CB  1 
ATOM   318  C CG  . LYS B 1 16 ? 97.956  102.613 115.767 1.00 20.89  ? 16 LYS BB CG  1 
ATOM   319  C CD  . LYS B 1 16 ? 98.618  101.285 115.503 1.00 22.06  ? 16 LYS BB CD  1 
ATOM   320  C CE  . LYS B 1 16 ? 97.837  100.157 116.132 1.00 22.83  ? 16 LYS BB CE  1 
ATOM   321  N NZ  . LYS B 1 16 ? 98.642  98.914  116.159 1.00 28.31  ? 16 LYS BB NZ  1 
ATOM   322  N N   . LEU B 1 17 ? 99.398  107.267 115.629 1.00 23.96  ? 17 LEU BB N   1 
ATOM   323  C CA  . LEU B 1 17 ? 100.044 108.449 115.082 1.00 25.08  ? 17 LEU BB CA  1 
ATOM   324  C C   . LEU B 1 17 ? 101.443 108.583 115.661 1.00 25.06  ? 17 LEU BB C   1 
ATOM   325  O O   . LEU B 1 17 ? 101.626 108.495 116.878 1.00 32.20  ? 17 LEU BB O   1 
ATOM   326  C CB  . LEU B 1 17 ? 99.224  109.702 115.386 1.00 25.85  ? 17 LEU BB CB  1 
ATOM   327  C CG  . LEU B 1 17 ? 99.555  110.955 114.579 1.00 28.96  ? 17 LEU BB CG  1 
ATOM   328  C CD1 . LEU B 1 17 ? 98.276  111.631 114.137 1.00 37.70  ? 17 LEU BB CD1 1 
ATOM   329  C CD2 . LEU B 1 17 ? 100.411 111.909 115.388 1.00 27.85  ? 17 LEU BB CD2 1 
ATOM   330  N N   . VAL B 1 18 ? 102.424 108.789 114.789 1.00 24.89  ? 18 VAL BB N   1 
ATOM   331  C CA  . VAL B 1 18 ? 103.788 109.109 115.189 1.00 26.58  ? 18 VAL BB CA  1 
ATOM   332  C C   . VAL B 1 18 ? 104.155 110.443 114.560 1.00 29.85  ? 18 VAL BB C   1 
ATOM   333  O O   . VAL B 1 18 ? 104.025 110.618 113.344 1.00 35.03  ? 18 VAL BB O   1 
ATOM   334  C CB  . VAL B 1 18 ? 104.785 108.014 114.775 1.00 25.75  ? 18 VAL BB CB  1 
ATOM   335  C CG1 . VAL B 1 18 ? 106.103 108.222 115.481 1.00 24.22  ? 18 VAL BB CG1 1 
ATOM   336  C CG2 . VAL B 1 18 ? 104.228 106.645 115.097 1.00 24.63  ? 18 VAL BB CG2 1 
ATOM   337  N N   . PHE B 1 19 ? 104.609 111.379 115.386 1.00 30.43  ? 19 PHE BB N   1 
ATOM   338  C CA  . PHE B 1 19 ? 104.887 112.743 114.959 1.00 32.79  ? 19 PHE BB CA  1 
ATOM   339  C C   . PHE B 1 19 ? 106.334 113.078 115.281 1.00 36.31  ? 19 PHE BB C   1 
ATOM   340  O O   . PHE B 1 19 ? 106.723 113.098 116.452 1.00 43.04  ? 19 PHE BB O   1 
ATOM   341  C CB  . PHE B 1 19 ? 103.938 113.724 115.651 1.00 36.08  ? 19 PHE BB CB  1 
ATOM   342  C CG  . PHE B 1 19 ? 103.859 115.066 114.991 1.00 38.70  ? 19 PHE BB CG  1 
ATOM   343  C CD1 . PHE B 1 19 ? 104.883 115.985 115.129 1.00 38.82  ? 19 PHE BB CD1 1 
ATOM   344  C CD2 . PHE B 1 19 ? 102.751 115.416 114.244 1.00 41.78  ? 19 PHE BB CD2 1 
ATOM   345  C CE1 . PHE B 1 19 ? 104.808 117.220 114.527 1.00 39.93  ? 19 PHE BB CE1 1 
ATOM   346  C CE2 . PHE B 1 19 ? 102.672 116.652 113.641 1.00 44.10  ? 19 PHE BB CE2 1 
ATOM   347  C CZ  . PHE B 1 19 ? 103.701 117.554 113.783 1.00 44.51  ? 19 PHE BB CZ  1 
ATOM   348  N N   . PHE B 1 20 ? 107.124 113.342 114.247 1.00 35.86  ? 20 PHE BB N   1 
ATOM   349  C CA  . PHE B 1 20 ? 108.500 113.791 114.396 1.00 37.59  ? 20 PHE BB CA  1 
ATOM   350  C C   . PHE B 1 20 ? 108.576 115.267 114.041 1.00 45.25  ? 20 PHE BB C   1 
ATOM   351  O O   . PHE B 1 20 ? 108.055 115.685 113.003 1.00 55.23  ? 20 PHE BB O   1 
ATOM   352  C CB  . PHE B 1 20 ? 109.450 112.999 113.499 1.00 39.09  ? 20 PHE BB CB  1 
ATOM   353  C CG  . PHE B 1 20 ? 109.600 111.560 113.884 1.00 38.58  ? 20 PHE BB CG  1 
ATOM   354  C CD1 . PHE B 1 20 ? 108.759 110.600 113.357 1.00 36.65  ? 20 PHE BB CD1 1 
ATOM   355  C CD2 . PHE B 1 20 ? 110.596 111.163 114.753 1.00 35.18  ? 20 PHE BB CD2 1 
ATOM   356  C CE1 . PHE B 1 20 ? 108.903 109.276 113.700 1.00 33.87  ? 20 PHE BB CE1 1 
ATOM   357  C CE2 . PHE B 1 20 ? 110.742 109.839 115.099 1.00 34.77  ? 20 PHE BB CE2 1 
ATOM   358  C CZ  . PHE B 1 20 ? 109.894 108.895 114.572 1.00 31.87  ? 20 PHE BB CZ  1 
ATOM   359  N N   . ALA B 1 21 ? 109.217 116.051 114.898 1.00 46.71  ? 21 ALA BB N   1 
ATOM   360  C CA  . ALA B 1 21 ? 109.428 117.467 114.646 1.00 51.62  ? 21 ALA BB CA  1 
ATOM   361  C C   . ALA B 1 21 ? 110.879 117.814 114.931 1.00 59.08  ? 21 ALA BB C   1 
ATOM   362  O O   . ALA B 1 21 ? 111.453 117.352 115.920 1.00 64.50  ? 21 ALA BB O   1 
ATOM   363  C CB  . ALA B 1 21 ? 108.500 118.334 115.500 1.00 47.68  ? 21 ALA BB CB  1 
ATOM   364  N N   . GLU B 1 22 ? 111.470 118.619 114.058 1.00 62.23  ? 22 GLU BB N   1 
ATOM   365  C CA  . GLU B 1 22 ? 112.848 119.052 114.239 1.00 69.45  ? 22 GLU BB CA  1 
ATOM   366  C C   . GLU B 1 22 ? 112.974 120.551 114.035 1.00 74.34  ? 22 GLU BB C   1 
ATOM   367  O O   . GLU B 1 22 ? 112.237 121.144 113.251 1.00 78.12  ? 22 GLU BB O   1 
ATOM   368  C CB  . GLU B 1 22 ? 113.777 118.312 113.281 1.00 72.05  ? 22 GLU BB CB  1 
ATOM   369  C CG  . GLU B 1 22 ? 114.175 116.934 113.759 1.00 71.84  ? 22 GLU BB CG  1 
ATOM   370  C CD  . GLU B 1 22 ? 115.625 116.866 114.188 1.00 75.14  ? 22 GLU BB CD  1 
ATOM   371  O OE1 . GLU B 1 22 ? 116.260 117.935 114.305 1.00 75.71  ? 22 GLU BB OE1 1 
ATOM   372  O OE2 . GLU B 1 22 ? 116.131 115.746 114.409 1.00 74.25  ? 22 GLU BB OE2 1 
HETATM 373  N N   . DAS B 1 23 ? 113.917 121.160 114.743 1.00 72.71  ? 23 DAS BB N   1 
HETATM 374  C CA  . DAS B 1 23 ? 114.108 122.599 114.673 1.00 76.75  ? 23 DAS BB CA  1 
HETATM 375  C C   . DAS B 1 23 ? 112.941 123.297 115.356 1.00 76.02  ? 23 DAS BB C   1 
HETATM 376  O O   . DAS B 1 23 ? 112.949 123.484 116.571 1.00 76.84  ? 23 DAS BB O   1 
HETATM 377  C CB  . DAS B 1 23 ? 115.426 122.991 115.342 1.00 83.90  ? 23 DAS BB CB  1 
HETATM 378  C CG  . DAS B 1 23 ? 115.804 124.436 115.084 1.00 88.14  ? 23 DAS BB CG  1 
HETATM 379  O OD1 . DAS B 1 23 ? 115.128 125.096 114.269 1.00 87.21  ? 23 DAS BB OD1 1 
HETATM 380  O OD2 . DAS B 1 23 ? 116.782 124.913 115.698 1.00 86.54  ? 23 DAS BB OD2 1 
ATOM   381  N N   . VAL B 1 24 ? 111.939 123.665 114.562 1.00 73.27  ? 24 VAL BB N   1 
ATOM   382  C CA  . VAL B 1 24 ? 110.741 124.346 115.049 1.00 69.90  ? 24 VAL BB CA  1 
ATOM   383  C C   . VAL B 1 24 ? 111.105 125.561 115.897 1.00 67.77  ? 24 VAL BB C   1 
ATOM   384  O O   . VAL B 1 24 ? 110.907 125.567 117.108 1.00 70.39  ? 24 VAL BB O   1 
ATOM   385  C CB  . VAL B 1 24 ? 109.836 123.384 115.837 1.00 64.79  ? 24 VAL BB CB  1 
ATOM   386  C CG1 . VAL B 1 24 ? 108.467 123.998 116.040 1.00 56.42  ? 24 VAL BB CG1 1 
ATOM   387  C CG2 . VAL B 1 24 ? 109.715 122.057 115.113 1.00 58.59  ? 24 VAL BB CG2 1 
ATOM   388  N N   . GLY B 1 25 ? 111.644 126.593 115.253 1.00 65.16  ? 25 GLY BB N   1 
ATOM   389  C CA  . GLY B 1 25 ? 112.078 127.790 115.947 1.00 63.72  ? 25 GLY BB CA  1 
ATOM   390  C C   . GLY B 1 25 ? 111.059 128.906 115.807 1.00 65.69  ? 25 GLY BB C   1 
ATOM   391  O O   . GLY B 1 25 ? 110.536 129.153 114.719 1.00 67.63  ? 25 GLY BB O   1 
ATOM   392  N N   . SER B 1 26 ? 110.788 129.575 116.928 1.00 66.41  ? 26 SER BB N   1 
ATOM   393  C CA  . SER B 1 26 ? 109.909 130.743 116.968 1.00 66.74  ? 26 SER BB CA  1 
ATOM   394  C C   . SER B 1 26 ? 108.532 130.429 116.384 1.00 62.57  ? 26 SER BB C   1 
ATOM   395  O O   . SER B 1 26 ? 107.973 131.195 115.598 1.00 59.58  ? 26 SER BB O   1 
ATOM   396  C CB  . SER B 1 26 ? 110.550 131.932 116.250 1.00 65.12  ? 26 SER BB CB  1 
ATOM   397  O OG  . SER B 1 26 ? 111.954 131.940 116.437 1.00 62.29  ? 26 SER BB OG  1 
ATOM   398  N N   . ASN B 1 27 ? 107.984 129.284 116.779 1.00 58.74  ? 27 ASN BB N   1 
ATOM   399  C CA  . ASN B 1 27 ? 106.654 128.897 116.329 1.00 53.96  ? 27 ASN BB CA  1 
ATOM   400  C C   . ASN B 1 27 ? 105.606 129.774 117.002 1.00 54.07  ? 27 ASN BB C   1 
ATOM   401  O O   . ASN B 1 27 ? 105.514 129.809 118.232 1.00 61.28  ? 27 ASN BB O   1 
ATOM   402  C CB  . ASN B 1 27 ? 106.397 127.426 116.636 1.00 53.66  ? 27 ASN BB CB  1 
ATOM   403  C CG  . ASN B 1 27 ? 104.921 127.090 116.680 1.00 48.69  ? 27 ASN BB CG  1 
ATOM   404  O OD1 . ASN B 1 27 ? 104.199 127.290 115.706 1.00 46.96  ? 27 ASN BB OD1 1 
ATOM   405  N ND2 . ASN B 1 27 ? 104.464 126.578 117.813 1.00 48.76  ? 27 ASN BB ND2 1 
ATOM   406  N N   . LYS B 1 28 ? 104.821 130.485 116.197 1.00 49.39  ? 28 LYS BB N   1 
ATOM   407  C CA  . LYS B 1 28 ? 103.728 131.303 116.698 1.00 50.70  ? 28 LYS BB CA  1 
ATOM   408  C C   . LYS B 1 28 ? 102.362 130.713 116.392 1.00 50.43  ? 28 LYS BB C   1 
ATOM   409  O O   . LYS B 1 28 ? 101.346 131.314 116.753 1.00 47.12  ? 28 LYS BB O   1 
ATOM   410  C CB  . LYS B 1 28 ? 103.820 132.720 116.124 1.00 51.94  ? 28 LYS BB CB  1 
ATOM   411  C CG  . LYS B 1 28 ? 105.171 133.377 116.328 1.00 54.88  ? 28 LYS BB CG  1 
ATOM   412  C CD  . LYS B 1 28 ? 105.052 134.889 116.342 1.00 56.29  ? 28 LYS BB CD  1 
ATOM   413  C CE  . LYS B 1 28 ? 106.419 135.548 116.394 1.00 61.55  ? 28 LYS BB CE  1 
ATOM   414  N NZ  . LYS B 1 28 ? 107.520 134.546 116.390 1.00 55.99  ? 28 LYS BB NZ  1 
ATOM   415  N N   . GLY B 1 29 ? 102.308 129.555 115.733 1.00 54.52  ? 29 GLY BB N   1 
ATOM   416  C CA  . GLY B 1 29 ? 101.073 128.895 115.412 1.00 50.66  ? 29 GLY BB CA  1 
ATOM   417  C C   . GLY B 1 29 ? 100.859 127.635 116.223 1.00 49.00  ? 29 GLY BB C   1 
ATOM   418  O O   . GLY B 1 29 ? 101.497 127.408 117.259 1.00 48.69  ? 29 GLY BB O   1 
ATOM   419  N N   . ALA B 1 30 ? 99.949  126.797 115.740 1.00 48.30  ? 30 ALA BB N   1 
ATOM   420  C CA  . ALA B 1 30 ? 99.588  125.553 116.405 1.00 41.05  ? 30 ALA BB CA  1 
ATOM   421  C C   . ALA B 1 30 ? 100.222 124.385 115.665 1.00 40.65  ? 30 ALA BB C   1 
ATOM   422  O O   . ALA B 1 30 ? 100.023 124.231 114.457 1.00 43.98  ? 30 ALA BB O   1 
ATOM   423  C CB  . ALA B 1 30 ? 98.071  125.388 116.467 1.00 35.72  ? 30 ALA BB CB  1 
ATOM   424  N N   . ILE B 1 31 ? 100.978 123.568 116.389 1.00 38.51  ? 31 ILE BB N   1 
ATOM   425  C CA  . ILE B 1 31 ? 101.554 122.337 115.861 1.00 37.05  ? 31 ILE BB CA  1 
ATOM   426  C C   . ILE B 1 31 ? 100.911 121.186 116.618 1.00 40.18  ? 31 ILE BB C   1 
ATOM   427  O O   . ILE B 1 31 ? 101.225 120.951 117.791 1.00 49.66  ? 31 ILE BB O   1 
ATOM   428  C CB  . ILE B 1 31 ? 103.079 122.313 115.999 1.00 33.50  ? 31 ILE BB CB  1 
ATOM   429  C CG1 . ILE B 1 31 ? 103.690 123.480 115.227 1.00 38.10  ? 31 ILE BB CG1 1 
ATOM   430  C CG2 . ILE B 1 31 ? 103.636 120.989 115.510 1.00 30.82  ? 31 ILE BB CG2 1 
ATOM   431  C CD1 . ILE B 1 31 ? 105.165 123.352 115.008 1.00 42.08  ? 31 ILE BB CD1 1 
ATOM   432  N N   . ILE B 1 32 ? 100.013 120.467 115.955 1.00 37.80  ? 32 ILE BB N   1 
ATOM   433  C CA  . ILE B 1 32 ? 99.197  119.443 116.592 1.00 42.84  ? 32 ILE BB CA  1 
ATOM   434  C C   . ILE B 1 32 ? 99.424  118.116 115.886 1.00 42.30  ? 32 ILE BB C   1 
ATOM   435  O O   . ILE B 1 32 ? 99.495  118.062 114.655 1.00 45.16  ? 32 ILE BB O   1 
ATOM   436  C CB  . ILE B 1 32 ? 97.702  119.821 116.578 1.00 44.85  ? 32 ILE BB CB  1 
ATOM   437  C CG1 . ILE B 1 32 ? 97.511  121.252 117.078 1.00 42.64  ? 32 ILE BB CG1 1 
ATOM   438  C CG2 . ILE B 1 32 ? 96.906  118.862 117.435 1.00 48.55  ? 32 ILE BB CG2 1 
ATOM   439  C CD1 . ILE B 1 32 ? 96.471  122.031 116.314 1.00 40.67  ? 32 ILE BB CD1 1 
ATOM   440  N N   . GLY B 1 33 ? 99.554  117.050 116.668 1.00 44.70  ? 33 GLY BB N   1 
ATOM   441  C CA  . GLY B 1 33 ? 99.665  115.721 116.104 1.00 40.70  ? 33 GLY BB CA  1 
ATOM   442  C C   . GLY B 1 33 ? 98.336  115.216 115.587 1.00 40.23  ? 33 GLY BB C   1 
ATOM   443  O O   . GLY B 1 33 ? 98.193  114.930 114.397 1.00 43.73  ? 33 GLY BB O   1 
ATOM   444  N N   . LEU B 1 34 ? 97.354  115.098 116.476 1.00 41.37  ? 34 LEU BB N   1 
ATOM   445  C CA  . LEU B 1 34 ? 95.995  114.727 116.106 1.00 41.56  ? 34 LEU BB CA  1 
ATOM   446  C C   . LEU B 1 34 ? 95.052  115.770 116.680 1.00 43.59  ? 34 LEU BB C   1 
ATOM   447  O O   . LEU B 1 34 ? 95.049  116.002 117.892 1.00 52.62  ? 34 LEU BB O   1 
ATOM   448  C CB  . LEU B 1 34 ? 95.635  113.335 116.627 1.00 42.98  ? 34 LEU BB CB  1 
ATOM   449  C CG  . LEU B 1 34 ? 94.401  112.673 116.014 1.00 39.98  ? 34 LEU BB CG  1 
ATOM   450  C CD1 . LEU B 1 34 ? 94.715  111.239 115.631 1.00 33.09  ? 34 LEU BB CD1 1 
ATOM   451  C CD2 . LEU B 1 34 ? 93.215  112.732 116.956 1.00 40.03  ? 34 LEU BB CD2 1 
ATOM   452  N N   . MET B 1 35 ? 94.257  116.394 115.819 1.00 38.84  ? 35 MET BB N   1 
ATOM   453  C CA  . MET B 1 35 ? 93.332  117.439 116.229 1.00 44.10  ? 35 MET BB CA  1 
ATOM   454  C C   . MET B 1 35 ? 91.928  117.071 115.780 1.00 48.26  ? 35 MET BB C   1 
ATOM   455  O O   . MET B 1 35 ? 91.712  116.751 114.608 1.00 57.64  ? 35 MET BB O   1 
ATOM   456  C CB  . MET B 1 35 ? 93.737  118.791 115.643 1.00 46.59  ? 35 MET BB CB  1 
ATOM   457  C CG  . MET B 1 35 ? 92.622  119.812 115.637 1.00 51.67  ? 35 MET BB CG  1 
ATOM   458  S SD  . MET B 1 35 ? 92.644  120.891 117.070 1.00 73.51  ? 35 MET BB SD  1 
ATOM   459  C CE  . MET B 1 35 ? 91.010  121.608 116.977 1.00 71.03  ? 35 MET BB CE  1 
ATOM   460  N N   . VAL B 1 36 ? 90.980  117.112 116.710 1.00 48.97  ? 36 VAL BB N   1 
ATOM   461  C CA  . VAL B 1 36 ? 89.570  116.885 116.418 1.00 50.21  ? 36 VAL BB CA  1 
ATOM   462  C C   . VAL B 1 36 ? 88.801  118.105 116.897 1.00 56.88  ? 36 VAL BB C   1 
ATOM   463  O O   . VAL B 1 36 ? 88.930  118.508 118.059 1.00 64.00  ? 36 VAL BB O   1 
ATOM   464  C CB  . VAL B 1 36 ? 89.042  115.607 117.084 1.00 46.62  ? 36 VAL BB CB  1 
ATOM   465  C CG1 . VAL B 1 36 ? 87.558  115.449 116.814 1.00 48.09  ? 36 VAL BB CG1 1 
ATOM   466  C CG2 . VAL B 1 36 ? 89.810  114.396 116.589 1.00 41.47  ? 36 VAL BB CG2 1 
ATOM   467  N N   . GLY B 1 37 ? 88.005  118.691 116.010 1.00 56.15  ? 37 GLY BB N   1 
ATOM   468  C CA  . GLY B 1 37 ? 87.271  119.891 116.351 1.00 61.50  ? 37 GLY BB CA  1 
ATOM   469  C C   . GLY B 1 37 ? 87.350  120.956 115.278 1.00 74.49  ? 37 GLY BB C   1 
ATOM   470  O O   . GLY B 1 37 ? 86.892  120.743 114.153 1.00 81.43  ? 37 GLY BB O   1 
ATOM   471  N N   . GLY B 1 38 ? 87.914  122.105 115.612 1.00 77.39  ? 38 GLY BB N   1 
ATOM   472  C CA  . GLY B 1 38 ? 88.029  123.190 114.655 1.00 82.98  ? 38 GLY BB CA  1 
ATOM   473  C C   . GLY B 1 38 ? 89.233  124.051 114.952 1.00 87.96  ? 38 GLY BB C   1 
ATOM   474  O O   . GLY B 1 38 ? 89.533  124.352 116.112 1.00 86.27  ? 38 GLY BB O   1 
ATOM   475  N N   . VAL B 1 39 ? 89.923  124.458 113.891 1.00 90.26  ? 39 VAL BB N   1 
ATOM   476  C CA  . VAL B 1 39 ? 91.099  125.312 113.987 1.00 94.48  ? 39 VAL BB CA  1 
ATOM   477  C C   . VAL B 1 39 ? 90.808  126.608 113.247 1.00 97.76  ? 39 VAL BB C   1 
ATOM   478  O O   . VAL B 1 39 ? 90.478  126.589 112.056 1.00 93.80  ? 39 VAL BB O   1 
ATOM   479  C CB  . VAL B 1 39 ? 92.351  124.624 113.412 1.00 91.47  ? 39 VAL BB CB  1 
ATOM   480  C CG1 . VAL B 1 39 ? 93.449  125.642 113.163 1.00 90.96  ? 39 VAL BB CG1 1 
ATOM   481  C CG2 . VAL B 1 39 ? 92.835  123.540 114.356 1.00 86.64  ? 39 VAL BB CG2 1 
ATOM   482  N N   . VAL B 1 40 ? 90.924  127.728 113.954 1.00 101.84 ? 40 VAL BB N   1 
ATOM   483  C CA  . VAL B 1 40 ? 90.735  129.055 113.381 1.00 102.74 ? 40 VAL BB CA  1 
ATOM   484  C C   . VAL B 1 40 ? 92.036  129.823 113.553 1.00 105.52 ? 40 VAL BB C   1 
ATOM   485  O O   . VAL B 1 40 ? 92.532  129.968 114.677 1.00 105.13 ? 40 VAL BB O   1 
ATOM   486  C CB  . VAL B 1 40 ? 89.565  129.803 114.039 1.00 100.19 ? 40 VAL BB CB  1 
ATOM   487  C CG1 . VAL B 1 40 ? 89.362  131.152 113.374 1.00 98.42  ? 40 VAL BB CG1 1 
ATOM   488  C CG2 . VAL B 1 40 ? 88.296  128.971 113.962 1.00 97.85  ? 40 VAL BB CG2 1 
ATOM   489  N N   . ILE B 1 41 ? 92.584  130.313 112.447 1.00 108.51 ? 41 ILE BB N   1 
ATOM   490  C CA  . ILE B 1 41 ? 93.845  131.045 112.448 1.00 112.67 ? 41 ILE BB CA  1 
ATOM   491  C C   . ILE B 1 41 ? 93.562  132.498 112.101 1.00 116.23 ? 41 ILE BB C   1 
ATOM   492  O O   . ILE B 1 41 ? 92.921  132.790 111.083 1.00 115.97 ? 41 ILE BB O   1 
ATOM   493  C CB  . ILE B 1 41 ? 94.847  130.428 111.459 1.00 112.79 ? 41 ILE BB CB  1 
ATOM   494  C CG1 . ILE B 1 41 ? 94.966  128.923 111.694 1.00 107.76 ? 41 ILE BB CG1 1 
ATOM   495  C CG2 . ILE B 1 41 ? 96.205  131.096 111.594 1.00 110.95 ? 41 ILE BB CG2 1 
ATOM   496  C CD1 . ILE B 1 41 ? 95.805  128.216 110.659 1.00 104.16 ? 41 ILE BB CD1 1 
ATOM   497  N N   . ALA B 1 42 ? 94.037  133.409 112.943 1.00 118.92 ? 42 ALA BB N   1 
ATOM   498  C CA  . ALA B 1 42 ? 93.831  134.834 112.725 1.00 121.66 ? 42 ALA BB CA  1 
ATOM   499  C C   . ALA B 1 42 ? 95.044  135.634 113.188 1.00 127.02 ? 42 ALA BB C   1 
ATOM   500  O O   . ALA B 1 42 ? 95.908  135.120 113.898 1.00 129.60 ? 42 ALA BB O   1 
ATOM   501  C CB  . ALA B 1 42 ? 92.578  135.303 113.444 1.00 117.58 ? 42 ALA BB CB  1 
ATOM   502  O OXT . ALA B 1 42 ? 95.190  136.812 112.862 1.00 127.70 ? 42 ALA BB OXT 1 
ATOM   503  N N   . GLY C 1 9  ? 77.252  111.940 105.300 1.00 75.58  ? 9  GLY DD N   1 
ATOM   504  C CA  . GLY C 1 9  ? 78.130  111.287 106.253 1.00 77.59  ? 9  GLY DD CA  1 
ATOM   505  C C   . GLY C 1 9  ? 79.383  110.720 105.618 1.00 77.76  ? 9  GLY DD C   1 
ATOM   506  O O   . GLY C 1 9  ? 79.322  110.086 104.567 1.00 78.65  ? 9  GLY DD O   1 
ATOM   507  N N   . TYR C 1 10 ? 80.524  110.948 106.260 1.00 74.83  ? 10 TYR DD N   1 
ATOM   508  C CA  . TYR C 1 10 ? 81.814  110.484 105.770 1.00 70.87  ? 10 TYR DD CA  1 
ATOM   509  C C   . TYR C 1 10 ? 82.269  109.295 106.601 1.00 65.85  ? 10 TYR DD C   1 
ATOM   510  O O   . TYR C 1 10 ? 82.204  109.334 107.833 1.00 68.66  ? 10 TYR DD O   1 
ATOM   511  C CB  . TYR C 1 10 ? 82.864  111.595 105.830 1.00 71.13  ? 10 TYR DD CB  1 
ATOM   512  C CG  . TYR C 1 10 ? 82.534  112.827 105.018 1.00 81.03  ? 10 TYR DD CG  1 
ATOM   513  C CD1 . TYR C 1 10 ? 81.571  112.793 104.018 1.00 83.11  ? 10 TYR DD CD1 1 
ATOM   514  C CD2 . TYR C 1 10 ? 83.196  114.025 105.245 1.00 80.21  ? 10 TYR DD CD2 1 
ATOM   515  C CE1 . TYR C 1 10 ? 81.270  113.919 103.278 1.00 84.09  ? 10 TYR DD CE1 1 
ATOM   516  C CE2 . TYR C 1 10 ? 82.903  115.154 104.509 1.00 87.12  ? 10 TYR DD CE2 1 
ATOM   517  C CZ  . TYR C 1 10 ? 81.940  115.096 103.526 1.00 91.17  ? 10 TYR DD CZ  1 
ATOM   518  O OH  . TYR C 1 10 ? 81.646  116.219 102.789 1.00 91.09  ? 10 TYR DD OH  1 
ATOM   519  N N   . GLU C 1 11 ? 82.723  108.243 105.929 1.00 61.80  ? 11 GLU DD N   1 
ATOM   520  C CA  . GLU C 1 11 ? 83.258  107.054 106.586 1.00 57.88  ? 11 GLU DD CA  1 
ATOM   521  C C   . GLU C 1 11 ? 84.653  106.803 106.026 1.00 52.72  ? 11 GLU DD C   1 
ATOM   522  O O   . GLU C 1 11 ? 84.802  106.210 104.954 1.00 58.89  ? 11 GLU DD O   1 
ATOM   523  C CB  . GLU C 1 11 ? 82.350  105.849 106.377 1.00 61.88  ? 11 GLU DD CB  1 
ATOM   524  C CG  . GLU C 1 11 ? 82.526  104.764 107.421 1.00 65.71  ? 11 GLU DD CG  1 
ATOM   525  C CD  . GLU C 1 11 ? 81.801  103.485 107.060 1.00 76.41  ? 11 GLU DD CD  1 
ATOM   526  O OE1 . GLU C 1 11 ? 80.585  103.547 106.786 1.00 81.59  ? 11 GLU DD OE1 1 
ATOM   527  O OE2 . GLU C 1 11 ? 82.447  102.417 107.055 1.00 75.54  ? 11 GLU DD OE2 1 
ATOM   528  N N   . VAL C 1 12 ? 85.669  107.255 106.751 1.00 47.56  ? 12 VAL DD N   1 
ATOM   529  C CA  . VAL C 1 12 ? 87.062  107.130 106.342 1.00 41.82  ? 12 VAL DD CA  1 
ATOM   530  C C   . VAL C 1 12 ? 87.734  106.143 107.283 1.00 43.59  ? 12 VAL DD C   1 
ATOM   531  O O   . VAL C 1 12 ? 87.692  106.321 108.505 1.00 54.65  ? 12 VAL DD O   1 
ATOM   532  C CB  . VAL C 1 12 ? 87.775  108.490 106.366 1.00 38.02  ? 12 VAL DD CB  1 
ATOM   533  C CG1 . VAL C 1 12 ? 89.170  108.372 105.795 1.00 36.81  ? 12 VAL DD CG1 1 
ATOM   534  C CG2 . VAL C 1 12 ? 86.967  109.521 105.605 1.00 37.82  ? 12 VAL DD CG2 1 
ATOM   535  N N   . HIS C 1 13 ? 88.350  105.102 106.728 1.00 39.40  ? 13 HIS DD N   1 
ATOM   536  C CA  . HIS C 1 13 ? 89.035  104.135 107.572 1.00 42.52  ? 13 HIS DD CA  1 
ATOM   537  C C   . HIS C 1 13 ? 90.163  103.464 106.805 1.00 39.69  ? 13 HIS DD C   1 
ATOM   538  O O   . HIS C 1 13 ? 90.247  103.550 105.582 1.00 38.87  ? 13 HIS DD O   1 
ATOM   539  C CB  . HIS C 1 13 ? 88.077  103.078 108.140 1.00 45.91  ? 13 HIS DD CB  1 
ATOM   540  C CG  . HIS C 1 13 ? 87.090  102.541 107.151 1.00 46.41  ? 13 HIS DD CG  1 
ATOM   541  N ND1 . HIS C 1 13 ? 87.071  101.218 106.770 1.00 43.92  ? 13 HIS DD ND1 1 
ATOM   542  C CD2 . HIS C 1 13 ? 86.065  103.136 106.497 1.00 49.27  ? 13 HIS DD CD2 1 
ATOM   543  C CE1 . HIS C 1 13 ? 86.091  101.025 105.906 1.00 48.42  ? 13 HIS DD CE1 1 
ATOM   544  N NE2 . HIS C 1 13 ? 85.466  102.173 105.723 1.00 50.84  ? 13 HIS DD NE2 1 
ATOM   545  N N   . HIS C 1 14 ? 91.052  102.818 107.559 1.00 39.43  ? 14 HIS DD N   1 
ATOM   546  C CA  . HIS C 1 14 ? 92.147  102.014 107.018 1.00 36.41  ? 14 HIS DD CA  1 
ATOM   547  C C   . HIS C 1 14 ? 93.048  102.834 106.094 1.00 34.91  ? 14 HIS DD C   1 
ATOM   548  O O   . HIS C 1 14 ? 93.164  102.572 104.900 1.00 41.49  ? 14 HIS DD O   1 
ATOM   549  C CB  . HIS C 1 14 ? 91.608  100.770 106.311 1.00 37.87  ? 14 HIS DD CB  1 
ATOM   550  C CG  . HIS C 1 14 ? 90.963  99.791  107.238 1.00 43.65  ? 14 HIS DD CG  1 
ATOM   551  N ND1 . HIS C 1 14 ? 89.618  99.823  107.534 1.00 45.90  ? 14 HIS DD ND1 1 
ATOM   552  C CD2 . HIS C 1 14 ? 91.483  98.767  107.953 1.00 47.98  ? 14 HIS DD CD2 1 
ATOM   553  C CE1 . HIS C 1 14 ? 89.334  98.852  108.383 1.00 53.85  ? 14 HIS DD CE1 1 
ATOM   554  N NE2 . HIS C 1 14 ? 90.448  98.196  108.654 1.00 57.15  ? 14 HIS DD NE2 1 
ATOM   555  N N   . GLN C 1 15 ? 93.700  103.834 106.675 1.00 31.09  ? 15 GLN DD N   1 
ATOM   556  C CA  . GLN C 1 15 ? 94.640  104.679 105.954 1.00 25.82  ? 15 GLN DD CA  1 
ATOM   557  C C   . GLN C 1 15 ? 96.027  104.521 106.553 1.00 27.11  ? 15 GLN DD C   1 
ATOM   558  O O   . GLN C 1 15 ? 96.191  104.595 107.773 1.00 36.68  ? 15 GLN DD O   1 
ATOM   559  C CB  . GLN C 1 15 ? 94.214  106.145 106.003 1.00 26.86  ? 15 GLN DD CB  1 
ATOM   560  C CG  . GLN C 1 15 ? 93.444  106.594 104.788 1.00 36.02  ? 15 GLN DD CG  1 
ATOM   561  C CD  . GLN C 1 15 ? 91.961  106.403 104.954 1.00 36.75  ? 15 GLN DD CD  1 
ATOM   562  O OE1 . GLN C 1 15 ? 91.477  106.173 106.058 1.00 32.60  ? 15 GLN DD OE1 1 
ATOM   563  N NE2 . GLN C 1 15 ? 91.226  106.489 103.854 1.00 36.88  ? 15 GLN DD NE2 1 
ATOM   564  N N   . LYS C 1 16 ? 97.017  104.302 105.697 1.00 25.46  ? 16 LYS DD N   1 
ATOM   565  C CA  . LYS C 1 16 ? 98.421  104.271 106.096 1.00 23.75  ? 16 LYS DD CA  1 
ATOM   566  C C   . LYS C 1 16 ? 99.103  105.448 105.412 1.00 27.50  ? 16 LYS DD C   1 
ATOM   567  O O   . LYS C 1 16 ? 99.427  105.380 104.224 1.00 37.91  ? 16 LYS DD O   1 
ATOM   568  C CB  . LYS C 1 16 ? 99.078  102.951 105.722 1.00 23.54  ? 16 LYS DD CB  1 
ATOM   569  C CG  . LYS C 1 16 ? 98.388  101.742 106.299 1.00 20.89  ? 16 LYS DD CG  1 
ATOM   570  C CD  . LYS C 1 16 ? 99.189  100.493 106.036 1.00 22.06  ? 16 LYS DD CD  1 
ATOM   571  C CE  . LYS C 1 16 ? 98.535  99.287  106.665 1.00 22.83  ? 16 LYS DD CE  1 
ATOM   572  N NZ  . LYS C 1 16 ? 99.468  98.138  106.693 1.00 28.31  ? 16 LYS DD NZ  1 
ATOM   573  N N   . LEU C 1 17 ? 99.320  106.523 106.159 1.00 23.96  ? 17 LEU DD N   1 
ATOM   574  C CA  . LEU C 1 17 ? 99.836  107.768 105.612 1.00 25.08  ? 17 LEU DD CA  1 
ATOM   575  C C   . LEU C 1 17 ? 101.211 108.053 106.190 1.00 25.06  ? 17 LEU DD C   1 
ATOM   576  O O   . LEU C 1 17 ? 101.403 107.986 107.407 1.00 32.20  ? 17 LEU DD O   1 
ATOM   577  C CB  . LEU C 1 17 ? 98.885  108.926 105.915 1.00 25.85  ? 17 LEU DD CB  1 
ATOM   578  C CG  . LEU C 1 17 ? 99.079  110.206 105.107 1.00 28.96  ? 17 LEU DD CG  1 
ATOM   579  C CD1 . LEU C 1 17 ? 97.735  110.741 104.664 1.00 37.70  ? 17 LEU DD CD1 1 
ATOM   580  C CD2 . LEU C 1 17 ? 99.828  111.248 105.916 1.00 27.85  ? 17 LEU DD CD2 1 
ATOM   581  N N   . VAL C 1 18 ? 102.165 108.362 105.318 1.00 24.89  ? 18 VAL DD N   1 
ATOM   582  C CA  . VAL C 1 18 ? 103.486 108.828 105.718 1.00 26.58  ? 18 VAL DD CA  1 
ATOM   583  C C   . VAL C 1 18 ? 103.708 110.193 105.089 1.00 29.85  ? 18 VAL DD C   1 
ATOM   584  O O   . VAL C 1 18 ? 103.560 110.352 103.873 1.00 35.03  ? 18 VAL DD O   1 
ATOM   585  C CB  . VAL C 1 18 ? 104.596 107.847 105.305 1.00 25.75  ? 18 VAL DD CB  1 
ATOM   586  C CG1 . VAL C 1 18 ? 105.884 108.196 106.012 1.00 24.22  ? 18 VAL DD CG1 1 
ATOM   587  C CG2 . VAL C 1 18 ? 104.190 106.426 105.628 1.00 24.63  ? 18 VAL DD CG2 1 
ATOM   588  N N   . PHE C 1 19 ? 104.058 111.174 105.914 1.00 30.43  ? 19 PHE DD N   1 
ATOM   589  C CA  . PHE C 1 19 ? 104.187 112.560 105.487 1.00 32.79  ? 19 PHE DD CA  1 
ATOM   590  C C   . PHE C 1 19 ? 105.590 113.048 105.809 1.00 36.31  ? 19 PHE DD C   1 
ATOM   591  O O   . PHE C 1 19 ? 105.974 113.110 106.980 1.00 43.04  ? 19 PHE DD O   1 
ATOM   592  C CB  . PHE C 1 19 ? 103.139 113.432 106.178 1.00 36.08  ? 19 PHE DD CB  1 
ATOM   593  C CG  . PHE C 1 19 ? 102.915 114.758 105.517 1.00 38.70  ? 19 PHE DD CG  1 
ATOM   594  C CD1 . PHE C 1 19 ? 103.834 115.782 105.655 1.00 38.82  ? 19 PHE DD CD1 1 
ATOM   595  C CD2 . PHE C 1 19 ? 101.776 114.987 104.771 1.00 41.78  ? 19 PHE DD CD2 1 
ATOM   596  C CE1 . PHE C 1 19 ? 103.627 117.001 105.052 1.00 39.93  ? 19 PHE DD CE1 1 
ATOM   597  C CE2 . PHE C 1 19 ? 101.564 116.206 104.167 1.00 44.10  ? 19 PHE DD CE2 1 
ATOM   598  C CZ  . PHE C 1 19 ? 102.491 117.214 104.308 1.00 44.51  ? 19 PHE DD CZ  1 
ATOM   599  N N   . PHE C 1 20 ? 106.347 113.395 104.775 1.00 35.86  ? 20 PHE DD N   1 
ATOM   600  C CA  . PHE C 1 20 ? 107.667 113.991 104.924 1.00 37.59  ? 20 PHE DD CA  1 
ATOM   601  C C   . PHE C 1 20 ? 107.583 115.466 104.568 1.00 45.25  ? 20 PHE DD C   1 
ATOM   602  O O   . PHE C 1 20 ? 107.020 115.825 103.530 1.00 55.23  ? 20 PHE DD O   1 
ATOM   603  C CB  . PHE C 1 20 ? 108.697 113.304 104.027 1.00 39.09  ? 20 PHE DD CB  1 
ATOM   604  C CG  . PHE C 1 20 ? 109.001 111.890 104.413 1.00 38.58  ? 20 PHE DD CG  1 
ATOM   605  C CD1 . PHE C 1 20 ? 108.269 110.845 103.887 1.00 36.65  ? 20 PHE DD CD1 1 
ATOM   606  C CD2 . PHE C 1 20 ? 110.034 111.604 105.283 1.00 35.18  ? 20 PHE DD CD2 1 
ATOM   607  C CE1 . PHE C 1 20 ? 108.554 109.545 104.230 1.00 33.87  ? 20 PHE DD CE1 1 
ATOM   608  C CE2 . PHE C 1 20 ? 110.322 110.303 105.630 1.00 34.77  ? 20 PHE DD CE2 1 
ATOM   609  C CZ  . PHE C 1 20 ? 109.581 109.273 105.103 1.00 31.87  ? 20 PHE DD CZ  1 
ATOM   610  N N   . ALA C 1 21 ? 108.136 116.315 105.425 1.00 46.71  ? 21 ALA DD N   1 
ATOM   611  C CA  . ALA C 1 21 ? 108.193 117.745 105.172 1.00 51.62  ? 21 ALA DD CA  1 
ATOM   612  C C   . ALA C 1 21 ? 109.599 118.246 105.457 1.00 59.08  ? 21 ALA DD C   1 
ATOM   613  O O   . ALA C 1 21 ? 110.219 117.849 106.446 1.00 64.50  ? 21 ALA DD O   1 
ATOM   614  C CB  . ALA C 1 21 ? 107.177 118.507 106.025 1.00 47.68  ? 21 ALA DD CB  1 
ATOM   615  N N   . GLU C 1 22 ? 110.100 119.110 104.584 1.00 62.23  ? 22 GLU DD N   1 
ATOM   616  C CA  . GLU C 1 22 ? 111.423 119.688 104.765 1.00 69.45  ? 22 GLU DD CA  1 
ATOM   617  C C   . GLU C 1 22 ? 111.387 121.193 104.560 1.00 74.34  ? 22 GLU DD C   1 
ATOM   618  O O   . GLU C 1 22 ? 110.590 121.702 103.776 1.00 78.12  ? 22 GLU DD O   1 
ATOM   619  C CB  . GLU C 1 22 ? 112.426 119.053 103.808 1.00 72.05  ? 22 GLU DD CB  1 
ATOM   620  C CG  . GLU C 1 22 ? 112.970 117.726 104.286 1.00 71.84  ? 22 GLU DD CG  1 
ATOM   621  C CD  . GLU C 1 22 ? 114.419 117.815 104.716 1.00 75.14  ? 22 GLU DD CD  1 
ATOM   622  O OE1 . GLU C 1 22 ? 114.935 118.946 104.832 1.00 75.71  ? 22 GLU DD OE1 1 
ATOM   623  O OE2 . GLU C 1 22 ? 115.043 116.756 104.937 1.00 74.25  ? 22 GLU DD OE2 1 
HETATM 624  N N   . DAS C 1 23 ? 112.258 121.900 105.268 1.00 72.71  ? 23 DAS DD N   1 
HETATM 625  C CA  . DAS C 1 23 ? 112.293 123.351 105.197 1.00 76.75  ? 23 DAS DD CA  1 
HETATM 626  C C   . DAS C 1 23 ? 111.057 123.920 105.880 1.00 76.02  ? 23 DAS DD C   1 
HETATM 627  O O   . DAS C 1 23 ? 111.045 124.107 107.095 1.00 76.84  ? 23 DAS DD O   1 
HETATM 628  C CB  . DAS C 1 23 ? 113.560 123.884 105.866 1.00 83.90  ? 23 DAS DD CB  1 
HETATM 629  C CG  . DAS C 1 23 ? 113.782 125.361 105.608 1.00 88.14  ? 23 DAS DD CG  1 
HETATM 630  O OD1 . DAS C 1 23 ? 113.038 125.944 104.792 1.00 87.21  ? 23 DAS DD OD1 1 
HETATM 631  O OD2 . DAS C 1 23 ? 114.702 125.940 106.222 1.00 86.54  ? 23 DAS DD OD2 1 
ATOM   632  N N   . VAL C 1 24 ? 110.021 124.178 105.085 1.00 73.27  ? 24 VAL DD N   1 
ATOM   633  C CA  . VAL C 1 24 ? 108.757 124.725 105.572 1.00 69.90  ? 24 VAL DD CA  1 
ATOM   634  C C   . VAL C 1 24 ? 108.988 125.973 106.419 1.00 67.77  ? 24 VAL DD C   1 
ATOM   635  O O   . VAL C 1 24 ? 108.790 125.958 107.630 1.00 70.39  ? 24 VAL DD O   1 
ATOM   636  C CB  . VAL C 1 24 ? 107.961 123.672 106.361 1.00 64.79  ? 24 VAL DD CB  1 
ATOM   637  C CG1 . VAL C 1 24 ? 106.533 124.134 106.563 1.00 56.42  ? 24 VAL DD CG1 1 
ATOM   638  C CG2 . VAL C 1 24 ? 107.984 122.340 105.637 1.00 58.59  ? 24 VAL DD CG2 1 
ATOM   639  N N   . GLY C 1 25 ? 109.413 127.057 105.775 1.00 65.16  ? 25 GLY DD N   1 
ATOM   640  C CA  . GLY C 1 25 ? 109.715 128.294 106.468 1.00 63.72  ? 25 GLY DD CA  1 
ATOM   641  C C   . GLY C 1 25 ? 108.582 129.294 106.328 1.00 65.69  ? 25 GLY DD C   1 
ATOM   642  O O   . GLY C 1 25 ? 108.035 129.482 105.239 1.00 67.63  ? 25 GLY DD O   1 
ATOM   643  N N   . SER C 1 26 ? 108.240 129.930 107.448 1.00 66.41  ? 26 SER DD N   1 
ATOM   644  C CA  . SER C 1 26 ? 107.240 130.997 107.487 1.00 66.74  ? 26 SER DD CA  1 
ATOM   645  C C   . SER C 1 26 ? 105.906 130.536 106.904 1.00 62.57  ? 26 SER DD C   1 
ATOM   646  O O   . SER C 1 26 ? 105.268 131.237 106.117 1.00 59.58  ? 26 SER DD O   1 
ATOM   647  C CB  . SER C 1 26 ? 107.750 132.247 106.768 1.00 65.12  ? 26 SER DD CB  1 
ATOM   648  O OG  . SER C 1 26 ? 109.145 132.407 106.956 1.00 62.29  ? 26 SER DD OG  1 
ATOM   649  N N   . ASN C 1 27 ? 105.484 129.339 107.298 1.00 58.74  ? 27 ASN DD N   1 
ATOM   650  C CA  . ASN C 1 27 ? 104.203 128.811 106.849 1.00 53.96  ? 27 ASN DD CA  1 
ATOM   651  C C   . ASN C 1 27 ? 103.067 129.569 107.521 1.00 54.07  ? 27 ASN DD C   1 
ATOM   652  O O   . ASN C 1 27 ? 102.971 129.595 108.751 1.00 61.28  ? 27 ASN DD O   1 
ATOM   653  C CB  . ASN C 1 27 ? 104.106 127.320 107.157 1.00 53.66  ? 27 ASN DD CB  1 
ATOM   654  C CG  . ASN C 1 27 ? 102.675 126.827 107.200 1.00 48.69  ? 27 ASN DD CG  1 
ATOM   655  O OD1 . ASN C 1 27 ? 101.936 126.947 106.226 1.00 46.96  ? 27 ASN DD OD1 1 
ATOM   656  N ND2 . ASN C 1 27 ? 102.276 126.269 108.334 1.00 48.76  ? 27 ASN DD ND2 1 
ATOM   657  N N   . LYS C 1 28 ? 102.210 130.192 106.715 1.00 49.39  ? 28 LYS DD N   1 
ATOM   658  C CA  . LYS C 1 28 ? 101.036 130.887 107.217 1.00 50.70  ? 28 LYS DD CA  1 
ATOM   659  C C   . LYS C 1 28 ? 99.741  130.153 106.910 1.00 50.43  ? 28 LYS DD C   1 
ATOM   660  O O   . LYS C 1 28 ? 98.666  130.642 107.271 1.00 47.12  ? 28 LYS DD O   1 
ATOM   661  C CB  . LYS C 1 28 ? 100.974 132.306 106.641 1.00 51.94  ? 28 LYS DD CB  1 
ATOM   662  C CG  . LYS C 1 28 ? 102.247 133.104 106.845 1.00 54.88  ? 28 LYS DD CG  1 
ATOM   663  C CD  . LYS C 1 28 ? 101.965 134.595 106.858 1.00 56.29  ? 28 LYS DD CD  1 
ATOM   664  C CE  . LYS C 1 28 ? 103.253 135.397 106.911 1.00 61.55  ? 28 LYS DD CE  1 
ATOM   665  N NZ  . LYS C 1 28 ? 104.456 134.519 106.907 1.00 55.99  ? 28 LYS DD NZ  1 
ATOM   666  N N   . GLY C 1 29 ? 99.812  128.996 106.252 1.00 54.52  ? 29 GLY DD N   1 
ATOM   667  C CA  . GLY C 1 29 ? 98.655  128.207 105.931 1.00 50.66  ? 29 GLY DD CA  1 
ATOM   668  C C   . GLY C 1 29 ? 98.578  126.932 106.743 1.00 49.00  ? 29 GLY DD C   1 
ATOM   669  O O   . GLY C 1 29 ? 99.237  126.774 107.778 1.00 48.69  ? 29 GLY DD O   1 
ATOM   670  N N   . ALA C 1 30 ? 97.764  126.000 106.260 1.00 48.30  ? 30 ALA DD N   1 
ATOM   671  C CA  . ALA C 1 30 ? 97.539  124.725 106.926 1.00 41.05  ? 30 ALA DD CA  1 
ATOM   672  C C   . ALA C 1 30 ? 98.295  123.631 106.186 1.00 40.65  ? 30 ALA DD C   1 
ATOM   673  O O   . ALA C 1 30 ? 98.115  123.456 104.978 1.00 43.98  ? 30 ALA DD O   1 
ATOM   674  C CB  . ALA C 1 30 ? 96.048  124.397 106.987 1.00 35.72  ? 30 ALA DD CB  1 
ATOM   675  N N   . ILE C 1 31 ? 99.135  122.901 106.911 1.00 38.51  ? 31 ILE DD N   1 
ATOM   676  C CA  . ILE C 1 31 ? 99.840  121.739 106.384 1.00 37.05  ? 31 ILE DD CA  1 
ATOM   677  C C   . ILE C 1 31 ? 99.325  120.526 107.141 1.00 40.18  ? 31 ILE DD C   1 
ATOM   678  O O   . ILE C 1 31 ? 99.662  120.326 108.314 1.00 49.66  ? 31 ILE DD O   1 
ATOM   679  C CB  . ILE C 1 31 ? 101.359 121.880 106.521 1.00 33.50  ? 31 ILE DD CB  1 
ATOM   680  C CG1 . ILE C 1 31 ? 101.841 123.105 105.749 1.00 38.10  ? 31 ILE DD CG1 1 
ATOM   681  C CG2 . ILE C 1 31 ? 102.055 120.622 106.034 1.00 30.82  ? 31 ILE DD CG2 1 
ATOM   682  C CD1 . ILE C 1 31 ? 103.321 123.136 105.530 1.00 42.08  ? 31 ILE DD CD1 1 
ATOM   683  N N   . ILE C 1 32 ? 98.509  119.713 106.478 1.00 37.80  ? 32 ILE DD N   1 
ATOM   684  C CA  . ILE C 1 32 ? 97.809  118.608 107.116 1.00 42.84  ? 32 ILE DD CA  1 
ATOM   685  C C   . ILE C 1 32 ? 98.178  117.313 106.410 1.00 42.30  ? 32 ILE DD C   1 
ATOM   686  O O   . ILE C 1 32 ? 98.254  117.266 105.180 1.00 45.16  ? 32 ILE DD O   1 
ATOM   687  C CB  . ILE C 1 32 ? 96.282  118.823 107.101 1.00 44.85  ? 32 ILE DD CB  1 
ATOM   688  C CG1 . ILE C 1 32 ? 95.937  120.225 107.600 1.00 42.64  ? 32 ILE DD CG1 1 
ATOM   689  C CG2 . ILE C 1 32 ? 95.593  117.784 107.958 1.00 48.55  ? 32 ILE DD CG2 1 
ATOM   690  C CD1 . ILE C 1 32 ? 94.820  120.887 106.836 1.00 40.67  ? 32 ILE DD CD1 1 
ATOM   691  N N   . GLY C 1 33 ? 98.421  116.267 107.193 1.00 44.70  ? 33 GLY DD N   1 
ATOM   692  C CA  . GLY C 1 33 ? 98.675  114.958 106.630 1.00 40.70  ? 33 GLY DD CA  1 
ATOM   693  C C   . GLY C 1 33 ? 97.408  114.312 106.113 1.00 40.23  ? 33 GLY DD C   1 
ATOM   694  O O   . GLY C 1 33 ? 97.297  114.012 104.923 1.00 43.73  ? 33 GLY DD O   1 
ATOM   695  N N   . LEU C 1 34 ? 96.445  114.090 107.001 1.00 41.37  ? 34 LEU DD N   1 
ATOM   696  C CA  . LEU C 1 34 ? 95.133  113.574 106.631 1.00 41.56  ? 34 LEU DD CA  1 
ATOM   697  C C   . LEU C 1 34 ? 94.084  114.510 107.204 1.00 43.59  ? 34 LEU DD C   1 
ATOM   698  O O   . LEU C 1 34 ? 94.055  114.741 108.416 1.00 52.62  ? 34 LEU DD O   1 
ATOM   699  C CB  . LEU C 1 34 ? 94.926  112.151 107.153 1.00 42.98  ? 34 LEU DD CB  1 
ATOM   700  C CG  . LEU C 1 34 ? 93.770  111.360 106.540 1.00 39.98  ? 34 LEU DD CG  1 
ATOM   701  C CD1 . LEU C 1 34 ? 94.237  109.969 106.158 1.00 33.09  ? 34 LEU DD CD1 1 
ATOM   702  C CD2 . LEU C 1 34 ? 92.584  111.291 107.481 1.00 40.03  ? 34 LEU DD CD2 1 
ATOM   703  N N   . MET C 1 35 ? 93.226  115.044 106.344 1.00 38.84  ? 35 MET DD N   1 
ATOM   704  C CA  . MET C 1 35 ? 92.193  115.983 106.753 1.00 44.10  ? 35 MET DD CA  1 
ATOM   705  C C   . MET C 1 35 ? 90.837  115.466 106.303 1.00 48.26  ? 35 MET DD C   1 
ATOM   706  O O   . MET C 1 35 ? 90.657  115.124 105.132 1.00 57.64  ? 35 MET DD O   1 
ATOM   707  C CB  . MET C 1 35 ? 92.450  117.371 106.166 1.00 46.59  ? 35 MET DD CB  1 
ATOM   708  C CG  . MET C 1 35 ? 91.232  118.266 106.159 1.00 51.67  ? 35 MET DD CG  1 
ATOM   709  S SD  . MET C 1 35 ? 91.137  119.342 107.591 1.00 73.51  ? 35 MET DD SD  1 
ATOM   710  C CE  . MET C 1 35 ? 89.436  119.878 107.498 1.00 71.03  ? 35 MET DD CE  1 
ATOM   711  N N   . VAL C 1 36 ? 89.890  115.405 107.233 1.00 48.97  ? 36 VAL DD N   1 
ATOM   712  C CA  . VAL C 1 36 ? 88.513  115.028 106.941 1.00 50.21  ? 36 VAL DD CA  1 
ATOM   713  C C   . VAL C 1 36 ? 87.617  116.158 107.420 1.00 56.88  ? 36 VAL DD C   1 
ATOM   714  O O   . VAL C 1 36 ? 87.702  116.573 108.582 1.00 64.00  ? 36 VAL DD O   1 
ATOM   715  C CB  . VAL C 1 36 ? 88.126  113.700 107.608 1.00 46.62  ? 36 VAL DD CB  1 
ATOM   716  C CG1 . VAL C 1 36 ? 86.667  113.383 107.337 1.00 48.09  ? 36 VAL DD CG1 1 
ATOM   717  C CG2 . VAL C 1 36 ? 89.020  112.579 107.113 1.00 41.47  ? 36 VAL DD CG2 1 
ATOM   718  N N   . GLY C 1 37 ? 86.762  116.654 106.532 1.00 56.15  ? 37 GLY DD N   1 
ATOM   719  C CA  . GLY C 1 37 ? 85.904  117.769 106.872 1.00 61.50  ? 37 GLY DD CA  1 
ATOM   720  C C   . GLY C 1 37 ? 85.867  118.835 105.799 1.00 74.49  ? 37 GLY DD C   1 
ATOM   721  O O   . GLY C 1 37 ? 85.436  118.573 104.674 1.00 81.43  ? 37 GLY DD O   1 
ATOM   722  N N   . GLY C 1 38 ? 86.305  120.038 106.133 1.00 77.39  ? 38 GLY DD N   1 
ATOM   723  C CA  . GLY C 1 38 ? 86.303  121.129 105.174 1.00 82.98  ? 38 GLY DD CA  1 
ATOM   724  C C   . GLY C 1 38 ? 87.406  122.115 105.472 1.00 87.96  ? 38 GLY DD C   1 
ATOM   725  O O   . GLY C 1 38 ? 87.672  122.447 106.631 1.00 86.27  ? 38 GLY DD O   1 
ATOM   726  N N   . VAL C 1 39 ? 88.049  122.593 104.411 1.00 90.26  ? 39 VAL DD N   1 
ATOM   727  C CA  . VAL C 1 39 ? 89.126  123.569 104.506 1.00 94.48  ? 39 VAL DD CA  1 
ATOM   728  C C   . VAL C 1 39 ? 88.697  124.826 103.766 1.00 97.76  ? 39 VAL DD C   1 
ATOM   729  O O   . VAL C 1 39 ? 88.372  124.771 102.574 1.00 93.80  ? 39 VAL DD O   1 
ATOM   730  C CB  . VAL C 1 39 ? 90.445  123.020 103.932 1.00 91.47  ? 39 VAL DD CB  1 
ATOM   731  C CG1 . VAL C 1 39 ? 91.427  124.150 103.682 1.00 90.96  ? 39 VAL DD CG1 1 
ATOM   732  C CG2 . VAL C 1 39 ? 91.042  121.994 104.876 1.00 86.64  ? 39 VAL DD CG2 1 
ATOM   733  N N   . VAL C 1 40 ? 88.692  125.953 104.472 1.00 101.84 ? 40 VAL DD N   1 
ATOM   734  C CA  . VAL C 1 40 ? 88.360  127.251 103.898 1.00 102.74 ? 40 VAL DD CA  1 
ATOM   735  C C   . VAL C 1 40 ? 89.571  128.154 104.070 1.00 105.52 ? 40 VAL DD C   1 
ATOM   736  O O   . VAL C 1 40 ? 90.049  128.352 105.194 1.00 105.13 ? 40 VAL DD O   1 
ATOM   737  C CB  . VAL C 1 40 ? 87.117  127.868 104.555 1.00 100.19 ? 40 VAL DD CB  1 
ATOM   738  C CG1 . VAL C 1 40 ? 86.770  129.188 103.890 1.00 98.42  ? 40 VAL DD CG1 1 
ATOM   739  C CG2 . VAL C 1 40 ? 85.945  126.905 104.479 1.00 97.85  ? 40 VAL DD CG2 1 
ATOM   740  N N   . ILE C 1 41 ? 90.064  128.700 102.964 1.00 108.51 ? 41 ILE DD N   1 
ATOM   741  C CA  . ILE C 1 41 ? 91.238  129.563 102.964 1.00 112.67 ? 41 ILE DD CA  1 
ATOM   742  C C   . ILE C 1 41 ? 90.801  130.978 102.617 1.00 116.23 ? 41 ILE DD C   1 
ATOM   743  O O   . ILE C 1 41 ? 90.132  131.198 101.599 1.00 115.97 ? 41 ILE DD O   1 
ATOM   744  C CB  . ILE C 1 41 ? 92.302  129.058 101.976 1.00 112.79 ? 41 ILE DD CB  1 
ATOM   745  C CG1 . ILE C 1 41 ? 92.582  127.574 102.212 1.00 107.76 ? 41 ILE DD CG1 1 
ATOM   746  C CG2 . ILE C 1 41 ? 93.579  129.868 102.111 1.00 110.95 ? 41 ILE DD CG2 1 
ATOM   747  C CD1 . ILE C 1 41 ? 93.492  126.961 101.178 1.00 104.16 ? 41 ILE DD CD1 1 
ATOM   748  N N   . ALA C 1 42 ? 91.175  131.934 103.458 1.00 118.92 ? 42 ALA DD N   1 
ATOM   749  C CA  . ALA C 1 42 ? 90.817  133.329 103.240 1.00 121.66 ? 42 ALA DD CA  1 
ATOM   750  C C   . ALA C 1 42 ? 91.936  134.255 103.703 1.00 127.02 ? 42 ALA DD C   1 
ATOM   751  O O   . ALA C 1 42 ? 92.850  133.838 104.413 1.00 129.60 ? 42 ALA DD O   1 
ATOM   752  C CB  . ALA C 1 42 ? 89.520  133.661 103.958 1.00 117.58 ? 42 ALA DD CB  1 
ATOM   753  O OXT . ALA C 1 42 ? 91.954  135.442 103.376 1.00 127.70 ? 42 ALA DD OXT 1 
ATOM   754  N N   . GLY D 1 9  ? 76.994  110.369 100.578 1.00 75.58  ? 9  GLY EE N   1 
ATOM   755  C CA  . GLY D 1 9  ? 77.906  109.764 101.530 1.00 77.59  ? 9  GLY EE CA  1 
ATOM   756  C C   . GLY D 1 9  ? 79.187  109.266 100.893 1.00 77.76  ? 9  GLY EE C   1 
ATOM   757  O O   . GLY D 1 9  ? 79.160  108.631 99.841  1.00 78.65  ? 9  GLY EE O   1 
ATOM   758  N N   . TYR D 1 10 ? 80.315  109.554 101.535 1.00 74.83  ? 10 TYR EE N   1 
ATOM   759  C CA  . TYR D 1 10 ? 81.628  109.161 101.043 1.00 70.87  ? 10 TYR EE CA  1 
ATOM   760  C C   . TYR D 1 10 ? 82.147  107.997 101.872 1.00 65.85  ? 10 TYR EE C   1 
ATOM   761  O O   . TYR D 1 10 ? 82.081  108.031 103.105 1.00 68.66  ? 10 TYR EE O   1 
ATOM   762  C CB  . TYR D 1 10 ? 82.617  110.327 101.105 1.00 71.13  ? 10 TYR EE CB  1 
ATOM   763  C CG  . TYR D 1 10 ? 82.220  111.541 100.294 1.00 81.03  ? 10 TYR EE CG  1 
ATOM   764  C CD1 . TYR D 1 10 ? 81.260  111.456 99.295  1.00 83.11  ? 10 TYR EE CD1 1 
ATOM   765  C CD2 . TYR D 1 10 ? 82.817  112.772 100.523 1.00 80.21  ? 10 TYR EE CD2 1 
ATOM   766  C CE1 . TYR D 1 10 ? 80.898  112.566 98.557  1.00 84.09  ? 10 TYR EE CE1 1 
ATOM   767  C CE2 . TYR D 1 10 ? 82.463  113.885 99.789  1.00 87.12  ? 10 TYR EE CE2 1 
ATOM   768  C CZ  . TYR D 1 10 ? 81.505  113.776 98.807  1.00 91.17  ? 10 TYR EE CZ  1 
ATOM   769  O OH  . TYR D 1 10 ? 81.150  114.883 98.072  1.00 91.09  ? 10 TYR EE OH  1 
ATOM   770  N N   . GLU D 1 11 ? 82.657  106.972 101.198 1.00 61.80  ? 11 GLU EE N   1 
ATOM   771  C CA  . GLU D 1 11 ? 83.256  105.812 101.853 1.00 57.88  ? 11 GLU EE CA  1 
ATOM   772  C C   . GLU D 1 11 ? 84.662  105.638 101.292 1.00 52.72  ? 11 GLU EE C   1 
ATOM   773  O O   . GLU D 1 11 ? 84.842  105.055 100.219 1.00 58.89  ? 11 GLU EE O   1 
ATOM   774  C CB  . GLU D 1 11 ? 82.413  104.560 101.642 1.00 61.88  ? 11 GLU EE CB  1 
ATOM   775  C CG  . GLU D 1 11 ? 82.648  103.485 102.685 1.00 65.71  ? 11 GLU EE CG  1 
ATOM   776  C CD  . GLU D 1 11 ? 81.993  102.170 102.322 1.00 76.41  ? 11 GLU EE CD  1 
ATOM   777  O OE1 . GLU D 1 11 ? 80.775  102.166 102.048 1.00 81.59  ? 11 GLU EE OE1 1 
ATOM   778  O OE2 . GLU D 1 11 ? 82.696  101.138 102.315 1.00 75.54  ? 11 GLU EE OE2 1 
ATOM   779  N N   . VAL D 1 12 ? 85.653  106.143 102.017 1.00 47.56  ? 12 VAL EE N   1 
ATOM   780  C CA  . VAL D 1 12 ? 87.050  106.094 101.607 1.00 41.82  ? 12 VAL EE CA  1 
ATOM   781  C C   . VAL D 1 12 ? 87.774  105.143 102.546 1.00 43.59  ? 12 VAL EE C   1 
ATOM   782  O O   . VAL D 1 12 ? 87.723  105.316 103.769 1.00 54.65  ? 12 VAL EE O   1 
ATOM   783  C CB  . VAL D 1 12 ? 87.688  107.490 101.633 1.00 38.02  ? 12 VAL EE CB  1 
ATOM   784  C CG1 . VAL D 1 12 ? 89.087  107.448 101.061 1.00 36.81  ? 12 VAL EE CG1 1 
ATOM   785  C CG2 . VAL D 1 12 ? 86.825  108.477 100.874 1.00 37.82  ? 12 VAL EE CG2 1 
ATOM   786  N N   . HIS D 1 13 ? 88.446  104.138 101.989 1.00 39.40  ? 13 HIS EE N   1 
ATOM   787  C CA  . HIS D 1 13 ? 89.182  103.207 102.831 1.00 42.52  ? 13 HIS EE CA  1 
ATOM   788  C C   . HIS D 1 13 ? 90.344  102.600 102.063 1.00 39.69  ? 13 HIS EE C   1 
ATOM   789  O O   . HIS D 1 13 ? 90.423  102.692 100.840 1.00 38.87  ? 13 HIS EE O   1 
ATOM   790  C CB  . HIS D 1 13 ? 88.282  102.100 103.398 1.00 45.91  ? 13 HIS EE CB  1 
ATOM   791  C CG  . HIS D 1 13 ? 87.325  101.512 102.409 1.00 46.41  ? 13 HIS EE CG  1 
ATOM   792  N ND1 . HIS D 1 13 ? 87.378  100.190 102.025 1.00 43.92  ? 13 HIS EE ND1 1 
ATOM   793  C CD2 . HIS D 1 13 ? 86.270  102.051 101.756 1.00 49.27  ? 13 HIS EE CD2 1 
ATOM   794  C CE1 . HIS D 1 13 ? 86.409  99.946  101.162 1.00 48.42  ? 13 HIS EE CE1 1 
ATOM   795  N NE2 . HIS D 1 13 ? 85.722  101.059 100.981 1.00 50.84  ? 13 HIS EE NE2 1 
ATOM   796  N N   . HIS D 1 14 ? 91.267  102.001 102.815 1.00 39.43  ? 14 HIS EE N   1 
ATOM   797  C CA  . HIS D 1 14 ? 92.404  101.258 102.272 1.00 36.41  ? 14 HIS EE CA  1 
ATOM   798  C C   . HIS D 1 14 ? 93.258  102.127 101.349 1.00 34.91  ? 14 HIS EE C   1 
ATOM   799  O O   . HIS D 1 14 ? 93.387  101.873 100.155 1.00 41.49  ? 14 HIS EE O   1 
ATOM   800  C CB  . HIS D 1 14 ? 91.931  99.988  101.563 1.00 37.87  ? 14 HIS EE CB  1 
ATOM   801  C CG  . HIS D 1 14 ? 91.341  98.974  102.489 1.00 43.65  ? 14 HIS EE CG  1 
ATOM   802  N ND1 . HIS D 1 14 ? 89.996  98.933  102.786 1.00 45.90  ? 14 HIS EE ND1 1 
ATOM   803  C CD2 . HIS D 1 14 ? 91.915  97.978  103.202 1.00 47.98  ? 14 HIS EE CD2 1 
ATOM   804  C CE1 . HIS D 1 14 ? 89.766  97.946  103.633 1.00 53.85  ? 14 HIS EE CE1 1 
ATOM   805  N NE2 . HIS D 1 14 ? 90.914  97.352  103.902 1.00 57.15  ? 14 HIS EE NE2 1 
ATOM   806  N N   . GLN D 1 15 ? 93.856  103.160 101.931 1.00 31.09  ? 15 GLN EE N   1 
ATOM   807  C CA  . GLN D 1 15 ? 94.748  104.056 101.211 1.00 25.82  ? 15 GLN EE CA  1 
ATOM   808  C C   . GLN D 1 15 ? 96.142  103.971 101.809 1.00 27.11  ? 15 GLN EE C   1 
ATOM   809  O O   . GLN D 1 15 ? 96.303  104.052 103.030 1.00 36.68  ? 15 GLN EE O   1 
ATOM   810  C CB  . GLN D 1 15 ? 94.244  105.496 101.263 1.00 26.86  ? 15 GLN EE CB  1 
ATOM   811  C CG  . GLN D 1 15 ? 93.450  105.905 100.049 1.00 36.02  ? 15 GLN EE CG  1 
ATOM   812  C CD  . GLN D 1 15 ? 91.980  105.634 100.215 1.00 36.75  ? 15 GLN EE CD  1 
ATOM   813  O OE1 . GLN D 1 15 ? 91.509  105.376 101.319 1.00 32.60  ? 15 GLN EE OE1 1 
ATOM   814  N NE2 . GLN D 1 15 ? 91.241  105.682 99.116  1.00 36.88  ? 15 GLN EE NE2 1 
ATOM   815  N N   . LYS D 1 16 ? 97.142  103.807 100.952 1.00 25.46  ? 16 LYS EE N   1 
ATOM   816  C CA  . LYS D 1 16 ? 98.546  103.852 101.351 1.00 23.75  ? 16 LYS EE CA  1 
ATOM   817  C C   . LYS D 1 16 ? 99.163  105.064 100.668 1.00 27.50  ? 16 LYS EE C   1 
ATOM   818  O O   . LYS D 1 16 ? 99.490  105.016 99.480  1.00 37.91  ? 16 LYS EE O   1 
ATOM   819  C CB  . LYS D 1 16 ? 99.273  102.569 100.975 1.00 23.54  ? 16 LYS EE CB  1 
ATOM   820  C CG  . LYS D 1 16 ? 98.649  101.324 101.550 1.00 20.89  ? 16 LYS EE CG  1 
ATOM   821  C CD  . LYS D 1 16 ? 99.517  100.120 101.284 1.00 22.06  ? 16 LYS EE CD  1 
ATOM   822  C CE  . LYS D 1 16 ? 98.929  98.880  101.912 1.00 22.83  ? 16 LYS EE CE  1 
ATOM   823  N NZ  . LYS D 1 16 ? 99.923  97.783  101.937 1.00 28.31  ? 16 LYS EE NZ  1 
ATOM   824  N N   . LEU D 1 17 ? 99.323  106.149 101.417 1.00 23.96  ? 17 LEU EE N   1 
ATOM   825  C CA  . LEU D 1 17 ? 99.770  107.420 100.871 1.00 25.08  ? 17 LEU EE CA  1 
ATOM   826  C C   . LEU D 1 17 ? 101.129 107.778 101.450 1.00 25.06  ? 17 LEU EE C   1 
ATOM   827  O O   . LEU D 1 17 ? 101.324 107.719 102.666 1.00 32.20  ? 17 LEU EE O   1 
ATOM   828  C CB  . LEU D 1 17 ? 98.758  108.525 101.177 1.00 25.85  ? 17 LEU EE CB  1 
ATOM   829  C CG  . LEU D 1 17 ? 98.883  109.815 100.371 1.00 28.96  ? 17 LEU EE CG  1 
ATOM   830  C CD1 . LEU D 1 17 ? 97.512  110.277 99.930  1.00 37.70  ? 17 LEU EE CD1 1 
ATOM   831  C CD2 . LEU D 1 17 ? 99.574  110.894 101.181 1.00 27.85  ? 17 LEU EE CD2 1 
ATOM   832  N N   . VAL D 1 18 ? 102.064 108.140 100.578 1.00 24.89  ? 18 VAL EE N   1 
ATOM   833  C CA  . VAL D 1 18 ? 103.358 108.676 100.978 1.00 26.58  ? 18 VAL EE CA  1 
ATOM   834  C C   . VAL D 1 18 ? 103.505 110.052 100.351 1.00 29.85  ? 18 VAL EE C   1 
ATOM   835  O O   . VAL D 1 18 ? 103.348 110.205 99.135  1.00 35.03  ? 18 VAL EE O   1 
ATOM   836  C CB  . VAL D 1 18 ? 104.519 107.756 100.562 1.00 25.75  ? 18 VAL EE CB  1 
ATOM   837  C CG1 . VAL D 1 18 ? 105.786 108.173 101.269 1.00 24.22  ? 18 VAL EE CG1 1 
ATOM   838  C CG2 . VAL D 1 18 ? 104.190 106.315 100.883 1.00 24.63  ? 18 VAL EE CG2 1 
ATOM   839  N N   . PHE D 1 19 ? 103.803 111.048 101.177 1.00 30.43  ? 19 PHE EE N   1 
ATOM   840  C CA  . PHE D 1 19 ? 103.857 112.440 100.753 1.00 32.79  ? 19 PHE EE CA  1 
ATOM   841  C C   . PHE D 1 19 ? 105.232 113.002 101.074 1.00 36.31  ? 19 PHE EE C   1 
ATOM   842  O O   . PHE D 1 19 ? 105.613 113.084 102.245 1.00 43.04  ? 19 PHE EE O   1 
ATOM   843  C CB  . PHE D 1 19 ? 102.763 113.254 101.445 1.00 36.08  ? 19 PHE EE CB  1 
ATOM   844  C CG  . PHE D 1 19 ? 102.468 114.566 100.787 1.00 38.70  ? 19 PHE EE CG  1 
ATOM   845  C CD1 . PHE D 1 19 ? 103.331 115.638 100.926 1.00 38.82  ? 19 PHE EE CD1 1 
ATOM   846  C CD2 . PHE D 1 19 ? 101.318 114.734 100.041 1.00 41.78  ? 19 PHE EE CD2 1 
ATOM   847  C CE1 . PHE D 1 19 ? 103.058 116.846 100.325 1.00 39.93  ? 19 PHE EE CE1 1 
ATOM   848  C CE2 . PHE D 1 19 ? 101.040 115.942 99.439  1.00 44.10  ? 19 PHE EE CE2 1 
ATOM   849  C CZ  . PHE D 1 19 ? 101.911 116.998 99.582  1.00 44.51  ? 19 PHE EE CZ  1 
ATOM   850  N N   . PHE D 1 20 ? 105.969 113.392 100.040 1.00 35.86  ? 20 PHE EE N   1 
ATOM   851  C CA  . PHE D 1 20 ? 107.254 114.057 100.190 1.00 37.59  ? 20 PHE EE CA  1 
ATOM   852  C C   . PHE D 1 20 ? 107.091 115.526 99.836  1.00 45.25  ? 20 PHE EE C   1 
ATOM   853  O O   . PHE D 1 20 ? 106.509 115.856 98.799  1.00 55.23  ? 20 PHE EE O   1 
ATOM   854  C CB  . PHE D 1 20 ? 108.319 113.429 99.291  1.00 39.09  ? 20 PHE EE CB  1 
ATOM   855  C CG  . PHE D 1 20 ? 108.699 112.032 99.675  1.00 38.58  ? 20 PHE EE CG  1 
ATOM   856  C CD1 . PHE D 1 20 ? 108.024 110.950 99.147  1.00 36.65  ? 20 PHE EE CD1 1 
ATOM   857  C CD2 . PHE D 1 20 ? 109.746 111.801 100.544 1.00 35.18  ? 20 PHE EE CD2 1 
ATOM   858  C CE1 . PHE D 1 20 ? 108.379 109.666 99.488  1.00 33.87  ? 20 PHE EE CE1 1 
ATOM   859  C CE2 . PHE D 1 20 ? 110.104 110.517 100.888 1.00 34.77  ? 20 PHE EE CE2 1 
ATOM   860  C CZ  . PHE D 1 20 ? 109.419 109.449 100.360 1.00 31.87  ? 20 PHE EE CZ  1 
ATOM   861  N N   . ALA D 1 21 ? 107.597 116.402 100.695 1.00 46.71  ? 21 ALA EE N   1 
ATOM   862  C CA  . ALA D 1 21 ? 107.577 117.834 100.444 1.00 51.62  ? 21 ALA EE CA  1 
ATOM   863  C C   . ALA D 1 21 ? 108.954 118.410 100.729 1.00 59.08  ? 21 ALA EE C   1 
ATOM   864  O O   . ALA D 1 21 ? 109.595 118.045 101.717 1.00 64.50  ? 21 ALA EE O   1 
ATOM   865  C CB  . ALA D 1 21 ? 106.522 118.538 101.299 1.00 47.68  ? 21 ALA EE CB  1 
ATOM   866  N N   . GLU D 1 22 ? 109.407 119.301 99.857  1.00 62.23  ? 22 GLU EE N   1 
ATOM   867  C CA  . GLU D 1 22 ? 110.698 119.949 100.039 1.00 69.45  ? 22 GLU EE CA  1 
ATOM   868  C C   . GLU D 1 22 ? 110.580 121.450 99.836  1.00 74.34  ? 22 GLU EE C   1 
ATOM   869  O O   . GLU D 1 22 ? 109.757 121.917 99.053  1.00 78.12  ? 22 GLU EE O   1 
ATOM   870  C CB  . GLU D 1 22 ? 111.733 119.370 99.080  1.00 72.05  ? 22 GLU EE CB  1 
ATOM   871  C CG  . GLU D 1 22 ? 112.348 118.073 99.555  1.00 71.84  ? 22 GLU EE CG  1 
ATOM   872  C CD  . GLU D 1 22 ? 113.790 118.240 99.985  1.00 75.14  ? 22 GLU EE CD  1 
ATOM   873  O OE1 . GLU D 1 22 ? 114.245 119.397 100.103 1.00 75.71  ? 22 GLU EE OE1 1 
ATOM   874  O OE2 . GLU D 1 22 ? 114.470 117.216 100.204 1.00 74.25  ? 22 GLU EE OE2 1 
HETATM 875  N N   . DAS D 1 23 ? 111.413 122.202 100.545 1.00 72.71  ? 23 DAS EE N   1 
HETATM 876  C CA  . DAS D 1 23 ? 111.369 123.653 100.476 1.00 76.75  ? 23 DAS EE CA  1 
HETATM 877  C C   . DAS D 1 23 ? 110.105 124.153 101.160 1.00 76.02  ? 23 DAS EE C   1 
HETATM 878  O O   . DAS D 1 23 ? 110.083 124.338 102.376 1.00 76.84  ? 23 DAS EE O   1 
HETATM 879  C CB  . DAS D 1 23 ? 112.606 124.252 101.145 1.00 83.90  ? 23 DAS EE CB  1 
HETATM 880  C CG  . DAS D 1 23 ? 112.747 125.739 100.889 1.00 88.14  ? 23 DAS EE CG  1 
HETATM 881  O OD1 . DAS D 1 23 ? 111.973 126.283 100.075 1.00 87.21  ? 23 DAS EE OD1 1 
HETATM 882  O OD2 . DAS D 1 23 ? 113.635 126.366 101.504 1.00 86.54  ? 23 DAS EE OD2 1 
ATOM   883  N N   . VAL D 1 24 ? 109.056 124.356 100.367 1.00 73.27  ? 24 VAL EE N   1 
ATOM   884  C CA  . VAL D 1 24 ? 107.765 124.834 100.855 1.00 69.90  ? 24 VAL EE CA  1 
ATOM   885  C C   . VAL D 1 24 ? 107.928 126.091 101.704 1.00 67.77  ? 24 VAL EE C   1 
ATOM   886  O O   . VAL D 1 24 ? 107.732 126.063 102.915 1.00 70.39  ? 24 VAL EE O   1 
ATOM   887  C CB  . VAL D 1 24 ? 107.027 123.737 101.642 1.00 64.79  ? 24 VAL EE CB  1 
ATOM   888  C CG1 . VAL D 1 24 ? 105.576 124.122 101.846 1.00 56.42  ? 24 VAL EE CG1 1 
ATOM   889  C CG2 . VAL D 1 24 ? 107.121 122.410 100.916 1.00 58.59  ? 24 VAL EE CG2 1 
ATOM   890  N N   . GLY D 1 25 ? 108.294 127.197 101.062 1.00 65.16  ? 25 GLY EE N   1 
ATOM   891  C CA  . GLY D 1 25 ? 108.529 128.448 101.756 1.00 63.72  ? 25 GLY EE CA  1 
ATOM   892  C C   . GLY D 1 25 ? 107.344 129.385 101.619 1.00 65.69  ? 25 GLY EE C   1 
ATOM   893  O O   . GLY D 1 25 ? 106.787 129.545 100.531 1.00 67.63  ? 25 GLY EE O   1 
ATOM   894  N N   . SER D 1 26 ? 106.969 130.000 102.740 1.00 66.41  ? 26 SER EE N   1 
ATOM   895  C CA  . SER D 1 26 ? 105.913 131.011 102.781 1.00 66.74  ? 26 SER EE CA  1 
ATOM   896  C C   . SER D 1 26 ? 104.605 130.480 102.198 1.00 62.57  ? 26 SER EE C   1 
ATOM   897  O O   . SER D 1 26 ? 103.930 131.147 101.412 1.00 59.58  ? 26 SER EE O   1 
ATOM   898  C CB  . SER D 1 26 ? 106.354 132.288 102.064 1.00 65.12  ? 26 SER EE CB  1 
ATOM   899  O OG  . SER D 1 26 ? 107.739 132.523 102.252 1.00 62.29  ? 26 SER EE OG  1 
ATOM   900  N N   . ASN D 1 27 ? 104.248 129.261 102.591 1.00 58.74  ? 27 ASN EE N   1 
ATOM   901  C CA  . ASN D 1 27 ? 102.998 128.666 102.141 1.00 53.96  ? 27 ASN EE CA  1 
ATOM   902  C C   . ASN D 1 27 ? 101.823 129.361 102.815 1.00 54.07  ? 27 ASN EE C   1 
ATOM   903  O O   . ASN D 1 27 ? 101.726 129.380 104.045 1.00 61.28  ? 27 ASN EE O   1 
ATOM   904  C CB  . ASN D 1 27 ? 102.982 127.171 102.446 1.00 53.66  ? 27 ASN EE CB  1 
ATOM   905  C CG  . ASN D 1 27 ? 101.579 126.602 102.490 1.00 48.69  ? 27 ASN EE CG  1 
ATOM   906  O OD1 . ASN D 1 27 ? 100.834 126.684 101.517 1.00 46.96  ? 27 ASN EE OD1 1 
ATOM   907  N ND2 . ASN D 1 27 ? 101.211 126.022 103.623 1.00 48.76  ? 27 ASN EE ND2 1 
ATOM   908  N N   . LYS D 1 28 ? 100.933 129.938 102.011 1.00 49.39  ? 28 LYS EE N   1 
ATOM   909  C CA  . LYS D 1 28 ? 99.723  130.568 102.514 1.00 50.70  ? 28 LYS EE CA  1 
ATOM   910  C C   . LYS D 1 28 ? 98.470  129.765 102.206 1.00 50.43  ? 28 LYS EE C   1 
ATOM   911  O O   . LYS D 1 28 ? 97.370  130.195 102.569 1.00 47.12  ? 28 LYS EE O   1 
ATOM   912  C CB  . LYS D 1 28 ? 99.585  131.982 101.941 1.00 51.94  ? 28 LYS EE CB  1 
ATOM   913  C CG  . LYS D 1 28 ? 100.813 132.847 102.145 1.00 54.88  ? 28 LYS EE CG  1 
ATOM   914  C CD  . LYS D 1 28 ? 100.452 134.321 102.161 1.00 56.29  ? 28 LYS EE CD  1 
ATOM   915  C CE  . LYS D 1 28 ? 101.694 135.191 102.214 1.00 61.55  ? 28 LYS EE CE  1 
ATOM   916  N NZ  . LYS D 1 28 ? 102.942 134.380 102.208 1.00 55.99  ? 28 LYS EE NZ  1 
ATOM   917  N N   . GLY D 1 29 ? 98.603  128.615 101.546 1.00 54.52  ? 29 GLY EE N   1 
ATOM   918  C CA  . GLY D 1 29 ? 97.490  127.765 101.225 1.00 50.66  ? 29 GLY EE CA  1 
ATOM   919  C C   . GLY D 1 29 ? 97.482  126.486 102.035 1.00 49.00  ? 29 GLY EE C   1 
ATOM   920  O O   . GLY D 1 29 ? 98.149  126.363 103.070 1.00 48.69  ? 29 GLY EE O   1 
ATOM   921  N N   . ALA D 1 30 ? 96.719  125.513 101.550 1.00 48.30  ? 30 ALA EE N   1 
ATOM   922  C CA  . ALA D 1 30 ? 96.563  124.227 102.215 1.00 41.05  ? 30 ALA EE CA  1 
ATOM   923  C C   . ALA D 1 30 ? 97.377  123.176 101.473 1.00 40.65  ? 30 ALA EE C   1 
ATOM   924  O O   . ALA D 1 30 ? 97.206  122.994 100.264 1.00 43.98  ? 30 ALA EE O   1 
ATOM   925  C CB  . ALA D 1 30 ? 95.092  123.819 102.276 1.00 35.72  ? 30 ALA EE CB  1 
ATOM   926  N N   . ILE D 1 31 ? 98.255  122.491 102.196 1.00 38.51  ? 31 ILE EE N   1 
ATOM   927  C CA  . ILE D 1 31 ? 99.021  121.370 101.666 1.00 37.05  ? 31 ILE EE CA  1 
ATOM   928  C C   . ILE D 1 31 ? 98.573  120.130 102.422 1.00 40.18  ? 31 ILE EE C   1 
ATOM   929  O O   . ILE D 1 31 ? 98.921  119.947 103.594 1.00 49.66  ? 31 ILE EE O   1 
ATOM   930  C CB  . ILE D 1 31 ? 100.531 121.592 101.803 1.00 33.50  ? 31 ILE EE CB  1 
ATOM   931  C CG1 . ILE D 1 31 ? 100.946 122.843 101.033 1.00 38.10  ? 31 ILE EE CG1 1 
ATOM   932  C CG2 . ILE D 1 31 ? 101.293 120.375 101.313 1.00 30.82  ? 31 ILE EE CG2 1 
ATOM   933  C CD1 . ILE D 1 31 ? 102.422 122.954 100.814 1.00 42.08  ? 31 ILE EE CD1 1 
ATOM   934  N N   . ILE D 1 32 ? 97.802  119.275 101.758 1.00 37.80  ? 32 ILE EE N   1 
ATOM   935  C CA  . ILE D 1 32 ? 97.163  118.133 102.394 1.00 42.84  ? 32 ILE EE CA  1 
ATOM   936  C C   . ILE D 1 32 ? 97.600  116.861 101.687 1.00 42.30  ? 32 ILE EE C   1 
ATOM   937  O O   . ILE D 1 32 ? 97.679  116.820 100.456 1.00 45.16  ? 32 ILE EE O   1 
ATOM   938  C CB  . ILE D 1 32 ? 95.626  118.265 102.380 1.00 44.85  ? 32 ILE EE CB  1 
ATOM   939  C CG1 . ILE D 1 32 ? 95.207  119.646 102.883 1.00 42.64  ? 32 ILE EE CG1 1 
ATOM   940  C CG2 . ILE D 1 32 ? 94.995  117.189 103.237 1.00 48.55  ? 32 ILE EE CG2 1 
ATOM   941  C CD1 . ILE D 1 32 ? 94.055  120.248 102.119 1.00 40.67  ? 32 ILE EE CD1 1 
ATOM   942  N N   . GLY D 1 33 ? 97.900  115.828 102.467 1.00 44.70  ? 33 GLY EE N   1 
ATOM   943  C CA  . GLY D 1 33 ? 98.224  114.535 101.902 1.00 40.70  ? 33 GLY EE CA  1 
ATOM   944  C C   . GLY D 1 33 ? 96.994  113.824 101.384 1.00 40.23  ? 33 GLY EE C   1 
ATOM   945  O O   . GLY D 1 33 ? 96.898  113.519 100.194 1.00 43.73  ? 33 GLY EE O   1 
ATOM   946  N N   . LEU D 1 34 ? 96.044  113.548 102.273 1.00 41.37  ? 34 LEU EE N   1 
ATOM   947  C CA  . LEU D 1 34 ? 94.762  112.963 101.903 1.00 41.56  ? 34 LEU EE CA  1 
ATOM   948  C C   . LEU D 1 34 ? 93.664  113.840 102.478 1.00 43.59  ? 34 LEU EE C   1 
ATOM   949  O O   . LEU D 1 34 ? 93.623  114.067 103.690 1.00 52.62  ? 34 LEU EE O   1 
ATOM   950  C CB  . LEU D 1 34 ? 94.632  111.530 102.423 1.00 42.98  ? 34 LEU EE CB  1 
ATOM   951  C CG  . LEU D 1 34 ? 93.520  110.679 101.809 1.00 39.98  ? 34 LEU EE CG  1 
ATOM   952  C CD1 . LEU D 1 34 ? 94.061  109.315 101.424 1.00 33.09  ? 34 LEU EE CD1 1 
ATOM   953  C CD2 . LEU D 1 34 ? 92.340  110.545 102.751 1.00 40.03  ? 34 LEU EE CD2 1 
ATOM   954  N N   . MET D 1 35 ? 92.778  114.329 101.618 1.00 38.84  ? 35 MET EE N   1 
ATOM   955  C CA  . MET D 1 35 ? 91.697  115.210 102.030 1.00 44.10  ? 35 MET EE CA  1 
ATOM   956  C C   . MET D 1 35 ? 90.370  114.622 101.580 1.00 48.26  ? 35 MET EE C   1 
ATOM   957  O O   . MET D 1 35 ? 90.208  114.272 100.408 1.00 57.64  ? 35 MET EE O   1 
ATOM   958  C CB  . MET D 1 35 ? 91.878  116.610 101.445 1.00 46.59  ? 35 MET EE CB  1 
ATOM   959  C CG  . MET D 1 35 ? 90.613  117.438 101.440 1.00 51.67  ? 35 MET EE CG  1 
ATOM   960  S SD  . MET D 1 35 ? 90.462  118.505 102.874 1.00 73.51  ? 35 MET EE SD  1 
ATOM   961  C CE  . MET D 1 35 ? 88.733  118.949 102.783 1.00 71.03  ? 35 MET EE CE  1 
ATOM   962  N N   . VAL D 1 36 ? 89.428  114.508 102.511 1.00 48.97  ? 36 VAL EE N   1 
ATOM   963  C CA  . VAL D 1 36 ? 88.073  114.057 102.219 1.00 50.21  ? 36 VAL EE CA  1 
ATOM   964  C C   . VAL D 1 36 ? 87.118  115.137 102.700 1.00 56.88  ? 36 VAL EE C   1 
ATOM   965  O O   . VAL D 1 36 ? 87.181  115.554 103.862 1.00 64.00  ? 36 VAL EE O   1 
ATOM   966  C CB  . VAL D 1 36 ? 87.758  112.710 102.884 1.00 46.62  ? 36 VAL EE CB  1 
ATOM   967  C CG1 . VAL D 1 36 ? 86.319  112.315 102.613 1.00 48.09  ? 36 VAL EE CG1 1 
ATOM   968  C CG2 . VAL D 1 36 ? 88.712  111.639 102.386 1.00 41.47  ? 36 VAL EE CG2 1 
ATOM   969  N N   . GLY D 1 37 ? 86.237  115.587 101.813 1.00 56.15  ? 37 GLY EE N   1 
ATOM   970  C CA  . GLY D 1 37 ? 85.320  116.654 102.155 1.00 61.50  ? 37 GLY EE CA  1 
ATOM   971  C C   . GLY D 1 37 ? 85.226  117.718 101.084 1.00 74.49  ? 37 GLY EE C   1 
ATOM   972  O O   . GLY D 1 37 ? 84.808  117.436 99.959  1.00 81.43  ? 37 GLY EE O   1 
ATOM   973  N N   . GLY D 1 38 ? 85.598  118.943 101.419 1.00 77.39  ? 38 GLY EE N   1 
ATOM   974  C CA  . GLY D 1 38 ? 85.536  120.034 100.463 1.00 82.98  ? 38 GLY EE CA  1 
ATOM   975  C C   . GLY D 1 38 ? 86.585  121.077 100.762 1.00 87.96  ? 38 GLY EE C   1 
ATOM   976  O O   . GLY D 1 38 ? 86.834  121.421 101.921 1.00 86.27  ? 38 GLY EE O   1 
ATOM   977  N N   . VAL D 1 39 ? 87.201  121.590 99.701  1.00 90.26  ? 39 VAL EE N   1 
ATOM   978  C CA  . VAL D 1 39 ? 88.224  122.623 99.797  1.00 94.48  ? 39 VAL EE CA  1 
ATOM   979  C C   . VAL D 1 39 ? 87.727  123.856 99.059  1.00 97.76  ? 39 VAL EE C   1 
ATOM   980  O O   . VAL D 1 39 ? 87.404  123.785 97.868  1.00 93.80  ? 39 VAL EE O   1 
ATOM   981  C CB  . VAL D 1 39 ? 89.570  122.146 99.222  1.00 91.47  ? 39 VAL EE CB  1 
ATOM   982  C CG1 . VAL D 1 39 ? 90.489  123.328 98.973  1.00 90.96  ? 39 VAL EE CG1 1 
ATOM   983  C CG2 . VAL D 1 39 ? 90.222  121.153 100.164 1.00 86.64  ? 39 VAL EE CG2 1 
ATOM   984  N N   . VAL D 1 40 ? 87.662  124.980 99.767  1.00 101.84 ? 40 VAL EE N   1 
ATOM   985  C CA  . VAL D 1 40 ? 87.260  126.259 99.196  1.00 102.74 ? 40 VAL EE CA  1 
ATOM   986  C C   . VAL D 1 40 ? 88.421  127.226 99.369  1.00 105.52 ? 40 VAL EE C   1 
ATOM   987  O O   . VAL D 1 40 ? 88.888  127.448 100.493 1.00 105.13 ? 40 VAL EE O   1 
ATOM   988  C CB  . VAL D 1 40 ? 85.986  126.807 99.854  1.00 100.19 ? 40 VAL EE CB  1 
ATOM   989  C CG1 . VAL D 1 40 ? 85.568  128.108 99.191  1.00 98.42  ? 40 VAL EE CG1 1 
ATOM   990  C CG2 . VAL D 1 40 ? 84.867  125.783 99.777  1.00 97.85  ? 40 VAL EE CG2 1 
ATOM   991  N N   . ILE D 1 41 ? 88.883  127.800 98.263  1.00 108.51 ? 41 ILE EE N   1 
ATOM   992  C CA  . ILE D 1 41 ? 90.009  128.725 98.264  1.00 112.67 ? 41 ILE EE CA  1 
ATOM   993  C C   . ILE D 1 41 ? 89.495  130.114 97.919  1.00 116.23 ? 41 ILE EE C   1 
ATOM   994  O O   . ILE D 1 41 ? 88.815  130.300 96.902  1.00 115.97 ? 41 ILE EE O   1 
ATOM   995  C CB  . ILE D 1 41 ? 91.097  128.279 97.275  1.00 112.79 ? 41 ILE EE CB  1 
ATOM   996  C CG1 . ILE D 1 41 ? 91.458  126.812 97.508  1.00 107.76 ? 41 ILE EE CG1 1 
ATOM   997  C CG2 . ILE D 1 41 ? 92.329  129.157 97.410  1.00 110.95 ? 41 ILE EE CG2 1 
ATOM   998  C CD1 . ILE D 1 41 ? 92.399  126.251 96.472  1.00 104.16 ? 41 ILE EE CD1 1 
ATOM   999  N N   . ALA D 1 42 ? 89.818  131.088 98.762  1.00 118.92 ? 42 ALA EE N   1 
ATOM   1000 C CA  . ALA D 1 42 ? 89.385  132.462 98.546  1.00 121.66 ? 42 ALA EE CA  1 
ATOM   1001 C C   . ALA D 1 42 ? 90.453  133.447 99.010  1.00 127.02 ? 42 ALA EE C   1 
ATOM   1002 O O   . ALA D 1 42 ? 91.389  133.078 99.719  1.00 129.60 ? 42 ALA EE O   1 
ATOM   1003 C CB  . ALA D 1 42 ? 88.072  132.722 99.266  1.00 117.58 ? 42 ALA EE CB  1 
ATOM   1004 O OXT . ALA D 1 42 ? 90.407  134.633 98.685  1.00 127.70 ? 42 ALA EE OXT 1 
ATOM   1005 N N   . GLY E 1 9  ? 76.809  108.774 95.881  1.00 75.58  ? 9  GLY FF N   1 
ATOM   1006 C CA  . GLY E 1 9  ? 77.753  108.217 96.831  1.00 77.59  ? 9  GLY FF CA  1 
ATOM   1007 C C   . GLY E 1 9  ? 79.059  107.790 96.192  1.00 77.76  ? 9  GLY FF C   1 
ATOM   1008 O O   . GLY E 1 9  ? 79.065  107.156 95.140  1.00 78.65  ? 9  GLY FF O   1 
ATOM   1009 N N   . TYR E 1 10 ? 80.170  108.138 96.833  1.00 74.83  ? 10 TYR FF N   1 
ATOM   1010 C CA  . TYR E 1 10 ? 81.501  107.817 96.339  1.00 70.87  ? 10 TYR FF CA  1 
ATOM   1011 C C   . TYR E 1 10 ? 82.084  106.682 97.166  1.00 65.85  ? 10 TYR FF C   1 
ATOM   1012 O O   . TYR E 1 10 ? 82.018  106.712 98.399  1.00 68.66  ? 10 TYR FF O   1 
ATOM   1013 C CB  . TYR E 1 10 ? 82.426  109.035 96.400  1.00 71.13  ? 10 TYR FF CB  1 
ATOM   1014 C CG  . TYR E 1 10 ? 81.963  110.226 95.592  1.00 81.03  ? 10 TYR FF CG  1 
ATOM   1015 C CD1 . TYR E 1 10 ? 81.007  110.091 94.594  1.00 83.11  ? 10 TYR FF CD1 1 
ATOM   1016 C CD2 . TYR E 1 10 ? 82.493  111.488 95.821  1.00 80.21  ? 10 TYR FF CD2 1 
ATOM   1017 C CE1 . TYR E 1 10 ? 80.585  111.180 93.858  1.00 84.09  ? 10 TYR FF CE1 1 
ATOM   1018 C CE2 . TYR E 1 10 ? 82.078  112.581 95.089  1.00 87.12  ? 10 TYR FF CE2 1 
ATOM   1019 C CZ  . TYR E 1 10 ? 81.126  112.421 94.107  1.00 91.17  ? 10 TYR FF CZ  1 
ATOM   1020 O OH  . TYR E 1 10 ? 80.710  113.508 93.374  1.00 91.09  ? 10 TYR FF OH  1 
ATOM   1021 N N   . GLU E 1 11 ? 82.647  105.687 96.491  1.00 61.80  ? 11 GLU FF N   1 
ATOM   1022 C CA  . GLU E 1 11 ? 83.309  104.561 97.143  1.00 57.88  ? 11 GLU FF CA  1 
ATOM   1023 C C   . GLU E 1 11 ? 84.722  104.464 96.580  1.00 52.72  ? 11 GLU FF C   1 
ATOM   1024 O O   . GLU E 1 11 ? 84.932  103.892 95.506  1.00 58.89  ? 11 GLU FF O   1 
ATOM   1025 C CB  . GLU E 1 11 ? 82.535  103.266 96.933  1.00 61.88  ? 11 GLU FF CB  1 
ATOM   1026 C CG  . GLU E 1 11 ? 82.829  102.203 97.974  1.00 65.71  ? 11 GLU FF CG  1 
ATOM   1027 C CD  . GLU E 1 11 ? 82.246  100.855 97.610  1.00 76.41  ? 11 GLU FF CD  1 
ATOM   1028 O OE1 . GLU E 1 11 ? 81.030  100.786 97.338  1.00 81.59  ? 11 GLU FF OE1 1 
ATOM   1029 O OE2 . GLU E 1 11 ? 83.004  99.862  97.601  1.00 75.54  ? 11 GLU FF OE2 1 
ATOM   1030 N N   . VAL E 1 12 ? 85.685  105.020 97.305  1.00 47.56  ? 12 VAL FF N   1 
ATOM   1031 C CA  . VAL E 1 12 ? 87.082  105.047 96.892  1.00 41.82  ? 12 VAL FF CA  1 
ATOM   1032 C C   . VAL E 1 12 ? 87.858  104.136 97.830  1.00 43.59  ? 12 VAL FF C   1 
ATOM   1033 O O   . VAL E 1 12 ? 87.800  104.305 99.052  1.00 54.65  ? 12 VAL FF O   1 
ATOM   1034 C CB  . VAL E 1 12 ? 87.644  106.476 96.919  1.00 38.02  ? 12 VAL FF CB  1 
ATOM   1035 C CG1 . VAL E 1 12 ? 89.042  106.510 96.345  1.00 36.81  ? 12 VAL FF CG1 1 
ATOM   1036 C CG2 . VAL E 1 12 ? 86.728  107.416 96.162  1.00 37.82  ? 12 VAL FF CG2 1 
ATOM   1037 N N   . HIS E 1 13 ? 88.582  103.169 97.270  1.00 39.40  ? 13 HIS FF N   1 
ATOM   1038 C CA  . HIS E 1 13 ? 89.369  102.279 98.110  1.00 42.52  ? 13 HIS FF CA  1 
ATOM   1039 C C   . HIS E 1 13 ? 90.562  101.736 97.340  1.00 39.69  ? 13 HIS FF C   1 
ATOM   1040 O O   . HIS E 1 13 ? 90.633  101.834 96.117  1.00 38.87  ? 13 HIS FF O   1 
ATOM   1041 C CB  . HIS E 1 13 ? 88.531  101.124 98.677  1.00 45.91  ? 13 HIS FF CB  1 
ATOM   1042 C CG  . HIS E 1 13 ? 87.606  100.486 97.689  1.00 46.41  ? 13 HIS FF CG  1 
ATOM   1043 N ND1 . HIS E 1 13 ? 87.729  99.169  97.304  1.00 43.92  ? 13 HIS FF ND1 1 
ATOM   1044 C CD2 . HIS E 1 13 ? 86.522  100.969 97.038  1.00 49.27  ? 13 HIS FF CD2 1 
ATOM   1045 C CE1 . HIS E 1 13 ? 86.774  98.874  96.442  1.00 48.42  ? 13 HIS FF CE1 1 
ATOM   1046 N NE2 . HIS E 1 13 ? 86.028  99.949  96.263  1.00 50.84  ? 13 HIS FF NE2 1 
ATOM   1047 N N   . HIS E 1 14 ? 91.517  101.188 98.091  1.00 39.43  ? 14 HIS FF N   1 
ATOM   1048 C CA  . HIS E 1 14 ? 92.691  100.507 97.545  1.00 36.41  ? 14 HIS FF CA  1 
ATOM   1049 C C   . HIS E 1 14 ? 93.496  101.422 96.622  1.00 34.91  ? 14 HIS FF C   1 
ATOM   1050 O O   . HIS E 1 14 ? 93.636  101.177 95.427  1.00 41.49  ? 14 HIS FF O   1 
ATOM   1051 C CB  . HIS E 1 14 ? 92.287  99.215  96.836  1.00 37.87  ? 14 HIS FF CB  1 
ATOM   1052 C CG  . HIS E 1 14 ? 91.753  98.170  97.761  1.00 43.65  ? 14 HIS FF CG  1 
ATOM   1053 N ND1 . HIS E 1 14 ? 90.413  98.055  98.060  1.00 45.90  ? 14 HIS FF ND1 1 
ATOM   1054 C CD2 . HIS E 1 14 ? 92.382  97.205  98.473  1.00 47.98  ? 14 HIS FF CD2 1 
ATOM   1055 C CE1 . HIS E 1 14 ? 90.238  97.057  98.907  1.00 53.85  ? 14 HIS FF CE1 1 
ATOM   1056 N NE2 . HIS E 1 14 ? 91.417  96.525  99.174  1.00 57.15  ? 14 HIS FF NE2 1 
ATOM   1057 N N   . GLN E 1 15 ? 94.038  102.485 97.204  1.00 31.09  ? 15 GLN FF N   1 
ATOM   1058 C CA  . GLN E 1 15 ? 94.879  103.429 96.484  1.00 25.82  ? 15 GLN FF CA  1 
ATOM   1059 C C   . GLN E 1 15 ? 96.276  103.420 97.080  1.00 27.11  ? 15 GLN FF C   1 
ATOM   1060 O O   . GLN E 1 15 ? 96.434  103.507 98.300  1.00 36.68  ? 15 GLN FF O   1 
ATOM   1061 C CB  . GLN E 1 15 ? 94.297  104.840 96.538  1.00 26.86  ? 15 GLN FF CB  1 
ATOM   1062 C CG  . GLN E 1 15 ? 93.481  105.207 95.325  1.00 36.02  ? 15 GLN FF CG  1 
ATOM   1063 C CD  . GLN E 1 15 ? 92.028  104.856 95.493  1.00 36.75  ? 15 GLN FF CD  1 
ATOM   1064 O OE1 . GLN E 1 15 ? 91.574  104.572 96.598  1.00 32.60  ? 15 GLN FF OE1 1 
ATOM   1065 N NE2 . GLN E 1 15 ? 91.286  104.865 94.395  1.00 36.88  ? 15 GLN FF NE2 1 
ATOM   1066 N N   . LYS E 1 16 ? 97.283  103.310 96.221  1.00 25.46  ? 16 LYS FF N   1 
ATOM   1067 C CA  . LYS E 1 16 ? 98.682  103.431 96.618  1.00 23.75  ? 16 LYS FF CA  1 
ATOM   1068 C C   . LYS E 1 16 ? 99.232  104.675 95.936  1.00 27.50  ? 16 LYS FF C   1 
ATOM   1069 O O   . LYS E 1 16 ? 99.559  104.646 94.747  1.00 37.91  ? 16 LYS FF O   1 
ATOM   1070 C CB  . LYS E 1 16 ? 99.477  102.189 96.239  1.00 23.54  ? 16 LYS FF CB  1 
ATOM   1071 C CG  . LYS E 1 16 ? 98.923  100.912 96.814  1.00 20.89  ? 16 LYS FF CG  1 
ATOM   1072 C CD  . LYS E 1 16 ? 99.853  99.757  96.546  1.00 22.06  ? 16 LYS FF CD  1 
ATOM   1073 C CE  . LYS E 1 16 ? 99.334  98.487  97.173  1.00 22.83  ? 16 LYS FF CE  1 
ATOM   1074 N NZ  . LYS E 1 16 ? 100.386 97.445  97.196  1.00 28.31  ? 16 LYS FF NZ  1 
ATOM   1075 N N   . LEU E 1 17 ? 99.334  105.766 96.685  1.00 23.96  ? 17 LEU FF N   1 
ATOM   1076 C CA  . LEU E 1 17 ? 99.711  107.061 96.140  1.00 25.08  ? 17 LEU FF CA  1 
ATOM   1077 C C   . LEU E 1 17 ? 101.049 107.491 96.717  1.00 25.06  ? 17 LEU FF C   1 
ATOM   1078 O O   . LEU E 1 17 ? 101.249 107.442 97.933  1.00 32.20  ? 17 LEU FF O   1 
ATOM   1079 C CB  . LEU E 1 17 ? 98.641  108.109 96.448  1.00 25.85  ? 17 LEU FF CB  1 
ATOM   1080 C CG  . LEU E 1 17 ? 98.695  109.405 95.643  1.00 28.96  ? 17 LEU FF CG  1 
ATOM   1081 C CD1 . LEU E 1 17 ? 97.300  109.792 95.205  1.00 37.70  ? 17 LEU FF CD1 1 
ATOM   1082 C CD2 . LEU E 1 17 ? 99.328  110.519 96.454  1.00 27.85  ? 17 LEU FF CD2 1 
ATOM   1083 N N   . VAL E 1 18 ? 101.962 107.903 95.844  1.00 24.89  ? 18 VAL FF N   1 
ATOM   1084 C CA  . VAL E 1 18 ? 103.226 108.508 96.243  1.00 26.58  ? 18 VAL FF CA  1 
ATOM   1085 C C   . VAL E 1 18 ? 103.298 109.891 95.617  1.00 29.85  ? 18 VAL FF C   1 
ATOM   1086 O O   . VAL E 1 18 ? 103.131 110.036 94.402  1.00 35.03  ? 18 VAL FF O   1 
ATOM   1087 C CB  . VAL E 1 18 ? 104.434 107.653 95.825  1.00 25.75  ? 18 VAL FF CB  1 
ATOM   1088 C CG1 . VAL E 1 18 ? 105.678 108.137 96.530  1.00 24.22  ? 18 VAL FF CG1 1 
ATOM   1089 C CG2 . VAL E 1 18 ? 104.184 106.196 96.144  1.00 24.63  ? 18 VAL FF CG2 1 
ATOM   1090 N N   . PHE E 1 19 ? 103.542 110.901 96.444  1.00 30.43  ? 19 PHE FF N   1 
ATOM   1091 C CA  . PHE E 1 19 ? 103.520 112.294 96.021  1.00 32.79  ? 19 PHE FF CA  1 
ATOM   1092 C C   . PHE E 1 19 ? 104.863 112.930 96.341  1.00 36.31  ? 19 PHE FF C   1 
ATOM   1093 O O   . PHE E 1 19 ? 105.241 113.030 97.512  1.00 43.04  ? 19 PHE FF O   1 
ATOM   1094 C CB  . PHE E 1 19 ? 102.385 113.047 96.716  1.00 36.08  ? 19 PHE FF CB  1 
ATOM   1095 C CG  . PHE E 1 19 ? 102.018 114.342 96.059  1.00 38.70  ? 19 PHE FF CG  1 
ATOM   1096 C CD1 . PHE E 1 19 ? 102.822 115.458 96.198  1.00 38.82  ? 19 PHE FF CD1 1 
ATOM   1097 C CD2 . PHE E 1 19 ? 100.860 114.448 95.315  1.00 41.78  ? 19 PHE FF CD2 1 
ATOM   1098 C CE1 . PHE E 1 19 ? 102.484 116.650 95.599  1.00 39.93  ? 19 PHE FF CE1 1 
ATOM   1099 C CE2 . PHE E 1 19 ? 100.517 115.640 94.715  1.00 44.10  ? 19 PHE FF CE2 1 
ATOM   1100 C CZ  . PHE E 1 19 ? 101.329 116.741 94.858  1.00 44.51  ? 19 PHE FF CZ  1 
ATOM   1101 N N   . PHE E 1 20 ? 105.576 113.359 95.307  1.00 35.86  ? 20 PHE FF N   1 
ATOM   1102 C CA  . PHE E 1 20 ? 106.824 114.093 95.455  1.00 37.59  ? 20 PHE FF CA  1 
ATOM   1103 C C   . PHE E 1 20 ? 106.581 115.551 95.103  1.00 45.25  ? 20 PHE FF C   1 
ATOM   1104 O O   . PHE E 1 20 ? 105.980 115.850 94.067  1.00 55.23  ? 20 PHE FF O   1 
ATOM   1105 C CB  . PHE E 1 20 ? 107.920 113.524 94.554  1.00 39.09  ? 20 PHE FF CB  1 
ATOM   1106 C CG  . PHE E 1 20 ? 108.375 112.150 94.936  1.00 38.58  ? 20 PHE FF CG  1 
ATOM   1107 C CD1 . PHE E 1 20 ? 107.759 111.033 94.408  1.00 36.65  ? 20 PHE FF CD1 1 
ATOM   1108 C CD2 . PHE E 1 20 ? 109.435 111.974 95.803  1.00 35.18  ? 20 PHE FF CD2 1 
ATOM   1109 C CE1 . PHE E 1 20 ? 108.184 109.770 94.747  1.00 33.87  ? 20 PHE FF CE1 1 
ATOM   1110 C CE2 . PHE E 1 20 ? 109.863 110.711 96.146  1.00 34.77  ? 20 PHE FF CE2 1 
ATOM   1111 C CZ  . PHE E 1 20 ? 109.236 109.609 95.618  1.00 31.87  ? 20 PHE FF CZ  1 
ATOM   1112 N N   . ALA E 1 21 ? 107.041 116.453 95.962  1.00 46.71  ? 21 ALA FF N   1 
ATOM   1113 C CA  . ALA E 1 21 ? 106.943 117.881 95.713  1.00 51.62  ? 21 ALA FF CA  1 
ATOM   1114 C C   . ALA E 1 21 ? 108.287 118.531 95.996  1.00 59.08  ? 21 ALA FF C   1 
ATOM   1115 O O   . ALA E 1 21 ? 108.949 118.200 96.983  1.00 64.50  ? 21 ALA FF O   1 
ATOM   1116 C CB  . ALA E 1 21 ? 105.852 118.527 96.569  1.00 47.68  ? 21 ALA FF CB  1 
ATOM   1117 N N   . GLU E 1 22 ? 108.690 119.446 95.125  1.00 62.23  ? 22 GLU FF N   1 
ATOM   1118 C CA  . GLU E 1 22 ? 109.944 120.163 95.305  1.00 69.45  ? 22 GLU FF CA  1 
ATOM   1119 C C   . GLU E 1 22 ? 109.745 121.655 95.104  1.00 74.34  ? 22 GLU FF C   1 
ATOM   1120 O O   . GLU E 1 22 ? 108.896 122.077 94.323  1.00 78.12  ? 22 GLU FF O   1 
ATOM   1121 C CB  . GLU E 1 22 ? 111.008 119.641 94.344  1.00 72.05  ? 22 GLU FF CB  1 
ATOM   1122 C CG  . GLU E 1 22 ? 111.692 118.379 94.817  1.00 71.84  ? 22 GLU FF CG  1 
ATOM   1123 C CD  . GLU E 1 22 ? 113.124 118.623 95.245  1.00 75.14  ? 22 GLU FF CD  1 
ATOM   1124 O OE1 . GLU E 1 22 ? 113.516 119.803 95.364  1.00 75.71  ? 22 GLU FF OE1 1 
ATOM   1125 O OE2 . GLU E 1 22 ? 113.859 117.637 95.462  1.00 74.25  ? 22 GLU FF OE2 1 
HETATM 1126 N N   . DAS E 1 23 ? 110.537 122.451 95.812  1.00 72.71  ? 23 DAS FF N   1 
HETATM 1127 C CA  . DAS E 1 23 ? 110.415 123.897 95.745  1.00 76.75  ? 23 DAS FF CA  1 
HETATM 1128 C C   . DAS E 1 23 ? 109.126 124.327 96.431  1.00 76.02  ? 23 DAS FF C   1 
HETATM 1129 O O   . DAS E 1 23 ? 109.096 124.509 97.647  1.00 76.84  ? 23 DAS FF O   1 
HETATM 1130 C CB  . DAS E 1 23 ? 111.619 124.561 96.413  1.00 83.90  ? 23 DAS FF CB  1 
HETATM 1131 C CG  . DAS E 1 23 ? 111.679 126.054 96.159  1.00 88.14  ? 23 DAS FF CG  1 
HETATM 1132 O OD1 . DAS E 1 23 ? 110.875 126.556 95.345  1.00 87.21  ? 23 DAS FF OD1 1 
HETATM 1133 O OD2 . DAS E 1 23 ? 112.532 126.728 96.772  1.00 86.54  ? 23 DAS FF OD2 1 
ATOM   1134 N N   . VAL E 1 24 ? 108.067 124.474 95.640  1.00 73.27  ? 24 VAL FF N   1 
ATOM   1135 C CA  . VAL E 1 24 ? 106.752 124.881 96.130  1.00 69.90  ? 24 VAL FF CA  1 
ATOM   1136 C C   . VAL E 1 24 ? 106.849 126.144 96.980  1.00 67.77  ? 24 VAL FF C   1 
ATOM   1137 O O   . VAL E 1 24 ? 106.656 126.105 98.192  1.00 70.39  ? 24 VAL FF O   1 
ATOM   1138 C CB  . VAL E 1 24 ? 106.076 123.746 96.917  1.00 64.79  ? 24 VAL FF CB  1 
ATOM   1139 C CG1 . VAL E 1 24 ? 104.607 124.051 97.123  1.00 56.42  ? 24 VAL FF CG1 1 
ATOM   1140 C CG2 . VAL E 1 24 ? 106.241 122.426 96.190  1.00 58.59  ? 24 VAL FF CG2 1 
ATOM   1141 N N   . GLY E 1 25 ? 107.153 127.269 96.338  1.00 65.16  ? 25 GLY FF N   1 
ATOM   1142 C CA  . GLY E 1 25 ? 107.321 128.530 97.034  1.00 63.72  ? 25 GLY FF CA  1 
ATOM   1143 C C   . GLY E 1 25 ? 106.087 129.402 96.899  1.00 65.69  ? 25 GLY FF C   1 
ATOM   1144 O O   . GLY E 1 25 ? 105.521 129.533 95.812  1.00 67.63  ? 25 GLY FF O   1 
ATOM   1145 N N   . SER E 1 26 ? 105.681 129.995 98.022  1.00 66.41  ? 26 SER FF N   1 
ATOM   1146 C CA  . SER E 1 26 ? 104.572 130.947 98.065  1.00 66.74  ? 26 SER FF CA  1 
ATOM   1147 C C   . SER E 1 26 ? 103.294 130.347 97.483  1.00 62.57  ? 26 SER FF C   1 
ATOM   1148 O O   . SER E 1 26 ? 102.582 130.977 96.699  1.00 59.58  ? 26 SER FF O   1 
ATOM   1149 C CB  . SER E 1 26 ? 104.943 132.247 97.349  1.00 65.12  ? 26 SER FF CB  1 
ATOM   1150 O OG  . SER E 1 26 ? 106.313 132.556 97.535  1.00 62.29  ? 26 SER FF OG  1 
ATOM   1151 N N   . ASN E 1 27 ? 103.004 129.110 97.875  1.00 58.74  ? 27 ASN FF N   1 
ATOM   1152 C CA  . ASN E 1 27 ? 101.787 128.448 97.426  1.00 53.96  ? 27 ASN FF CA  1 
ATOM   1153 C C   . ASN E 1 27 ? 100.577 129.078 98.103  1.00 54.07  ? 27 ASN FF C   1 
ATOM   1154 O O   . ASN E 1 27 ? 100.482 129.091 99.333  1.00 61.28  ? 27 ASN FF O   1 
ATOM   1155 C CB  . ASN E 1 27 ? 101.852 126.955 97.731  1.00 53.66  ? 27 ASN FF CB  1 
ATOM   1156 C CG  . ASN E 1 27 ? 100.482 126.311 97.775  1.00 48.69  ? 27 ASN FF CG  1 
ATOM   1157 O OD1 . ASN E 1 27 ? 99.732  126.353 96.803  1.00 46.96  ? 27 ASN FF OD1 1 
ATOM   1158 N ND2 . ASN E 1 27 ? 100.148 125.710 98.908  1.00 48.76  ? 27 ASN FF ND2 1 
ATOM   1159 N N   . LYS E 1 28 ? 99.657  129.607 97.301  1.00 49.39  ? 28 LYS FF N   1 
ATOM   1160 C CA  . LYS E 1 28 ? 98.415  130.171 97.806  1.00 50.70  ? 28 LYS FF CA  1 
ATOM   1161 C C   . LYS E 1 28 ? 97.206  129.301 97.499  1.00 50.43  ? 28 LYS FF C   1 
ATOM   1162 O O   . LYS E 1 28 ? 96.086  129.671 97.864  1.00 47.12  ? 28 LYS FF O   1 
ATOM   1163 C CB  . LYS E 1 28 ? 98.200  131.575 97.234  1.00 51.94  ? 28 LYS FF CB  1 
ATOM   1164 C CG  . LYS E 1 28 ? 99.379  132.506 97.438  1.00 54.88  ? 28 LYS FF CG  1 
ATOM   1165 C CD  . LYS E 1 28 ? 98.939  133.957 97.456  1.00 56.29  ? 28 LYS FF CD  1 
ATOM   1166 C CE  . LYS E 1 28 ? 100.133 134.894 97.508  1.00 61.55  ? 28 LYS FF CE  1 
ATOM   1167 N NZ  . LYS E 1 28 ? 101.423 134.151 97.500  1.00 55.99  ? 28 LYS FF NZ  1 
ATOM   1168 N N   . GLY E 1 29 ? 97.400  128.160 96.838  1.00 54.52  ? 29 GLY FF N   1 
ATOM   1169 C CA  . GLY E 1 29 ? 96.334  127.252 96.518  1.00 50.66  ? 29 GLY FF CA  1 
ATOM   1170 C C   . GLY E 1 29 ? 96.397  125.974 97.326  1.00 49.00  ? 29 GLY FF C   1 
ATOM   1171 O O   . GLY E 1 29 ? 97.071  125.886 98.360  1.00 48.69  ? 29 GLY FF O   1 
ATOM   1172 N N   . ALA E 1 30 ? 95.687  124.961 96.841  1.00 48.30  ? 30 ALA FF N   1 
ATOM   1173 C CA  . ALA E 1 30 ? 95.602  123.668 97.505  1.00 41.05  ? 30 ALA FF CA  1 
ATOM   1174 C C   . ALA E 1 30 ? 96.470  122.664 96.761  1.00 40.65  ? 30 ALA FF C   1 
ATOM   1175 O O   . ALA E 1 30 ? 96.307  122.473 95.552  1.00 43.98  ? 30 ALA FF O   1 
ATOM   1176 C CB  . ALA E 1 30 ? 94.155  123.181 97.568  1.00 35.72  ? 30 ALA FF CB  1 
ATOM   1177 N N   . ILE E 1 31 ? 97.385  122.026 97.482  1.00 38.51  ? 31 ILE FF N   1 
ATOM   1178 C CA  . ILE E 1 31 ? 98.210  120.949 96.950  1.00 37.05  ? 31 ILE FF CA  1 
ATOM   1179 C C   . ILE E 1 31 ? 97.831  119.685 97.705  1.00 40.18  ? 31 ILE FF C   1 
ATOM   1180 O O   . ILE E 1 31 ? 98.190  119.520 98.877  1.00 49.66  ? 31 ILE FF O   1 
ATOM   1181 C CB  . ILE E 1 31 ? 99.706  121.252 97.085  1.00 33.50  ? 31 ILE FF CB  1 
ATOM   1182 C CG1 . ILE E 1 31 ? 100.051 122.524 96.316  1.00 38.10  ? 31 ILE FF CG1 1 
ATOM   1183 C CG2 . ILE E 1 31 ? 100.532 120.078 96.593  1.00 30.82  ? 31 ILE FF CG2 1 
ATOM   1184 C CD1 . ILE E 1 31 ? 101.519 122.715 96.094  1.00 42.08  ? 31 ILE FF CD1 1 
ATOM   1185 N N   . ILE E 1 32 ? 97.106  118.791 97.041  1.00 37.80  ? 32 ILE FF N   1 
ATOM   1186 C CA  . ILE E 1 32 ? 96.530  117.615 97.677  1.00 42.84  ? 32 ILE FF CA  1 
ATOM   1187 C C   . ILE E 1 32 ? 97.035  116.369 96.968  1.00 42.30  ? 32 ILE FF C   1 
ATOM   1188 O O   . ILE E 1 32 ? 97.114  116.333 95.737  1.00 45.16  ? 32 ILE FF O   1 
ATOM   1189 C CB  . ILE E 1 32 ? 94.989  117.664 97.666  1.00 44.85  ? 32 ILE FF CB  1 
ATOM   1190 C CG1 . ILE E 1 32 ? 94.496  119.019 98.170  1.00 42.64  ? 32 ILE FF CG1 1 
ATOM   1191 C CG2 . ILE E 1 32 ? 94.418  116.555 98.522  1.00 48.55  ? 32 ILE FF CG2 1 
ATOM   1192 C CD1 . ILE E 1 32 ? 93.313  119.559 97.409  1.00 40.67  ? 32 ILE FF CD1 1 
ATOM   1193 N N   . GLY E 1 33 ? 97.392  115.354 97.747  1.00 44.70  ? 33 GLY FF N   1 
ATOM   1194 C CA  . GLY E 1 33 ? 97.784  114.081 97.180  1.00 40.70  ? 33 GLY FF CA  1 
ATOM   1195 C C   . GLY E 1 33 ? 96.593  113.304 96.664  1.00 40.23  ? 33 GLY FF C   1 
ATOM   1196 O O   . GLY E 1 33 ? 96.512  112.996 95.473  1.00 43.73  ? 33 GLY FF O   1 
ATOM   1197 N N   . LEU E 1 34 ? 95.661  112.977 97.553  1.00 41.37  ? 34 LEU FF N   1 
ATOM   1198 C CA  . LEU E 1 34 ? 94.412  112.324 97.184  1.00 41.56  ? 34 LEU FF CA  1 
ATOM   1199 C C   . LEU E 1 34 ? 93.269  113.139 97.762  1.00 43.59  ? 34 LEU FF C   1 
ATOM   1200 O O   . LEU E 1 34 ? 93.218  113.363 98.974  1.00 52.62  ? 34 LEU FF O   1 
ATOM   1201 C CB  . LEU E 1 34 ? 94.360  110.885 97.703  1.00 42.98  ? 34 LEU FF CB  1 
ATOM   1202 C CG  . LEU E 1 34 ? 93.295  109.975 97.090  1.00 39.98  ? 34 LEU FF CG  1 
ATOM   1203 C CD1 . LEU E 1 34 ? 93.908  108.643 96.703  1.00 33.09  ? 34 LEU FF CD1 1 
ATOM   1204 C CD2 . LEU E 1 34 ? 92.126  109.777 98.033  1.00 40.03  ? 34 LEU FF CD2 1 
ATOM   1205 N N   . MET E 1 35 ? 92.357  113.580 96.904  1.00 38.84  ? 35 MET FF N   1 
ATOM   1206 C CA  . MET E 1 35 ? 91.230  114.401 97.318  1.00 44.10  ? 35 MET FF CA  1 
ATOM   1207 C C   . MET E 1 35 ? 89.936  113.742 96.870  1.00 48.26  ? 35 MET FF C   1 
ATOM   1208 O O   . MET E 1 35 ? 89.792  113.386 95.697  1.00 57.64  ? 35 MET FF O   1 
ATOM   1209 C CB  . MET E 1 35 ? 91.334  115.810 96.734  1.00 46.59  ? 35 MET FF CB  1 
ATOM   1210 C CG  . MET E 1 35 ? 90.027  116.568 96.732  1.00 51.67  ? 35 MET FF CG  1 
ATOM   1211 S SD  . MET E 1 35 ? 89.820  117.624 98.167  1.00 73.51  ? 35 MET FF SD  1 
ATOM   1212 C CE  . MET E 1 35 ? 88.070  117.974 98.079  1.00 71.03  ? 35 MET FF CE  1 
ATOM   1213 N N   . VAL E 1 36 ? 89.003  113.577 97.801  1.00 48.97  ? 36 VAL FF N   1 
ATOM   1214 C CA  . VAL E 1 36 ? 87.675  113.054 97.510  1.00 50.21  ? 36 VAL FF CA  1 
ATOM   1215 C C   . VAL E 1 36 ? 86.663  114.080 97.994  1.00 56.88  ? 36 VAL FF C   1 
ATOM   1216 O O   . VAL E 1 36 ? 86.705  114.499 99.157  1.00 64.00  ? 36 VAL FF O   1 
ATOM   1217 C CB  . VAL E 1 36 ? 87.434  111.691 98.174  1.00 46.62  ? 36 VAL FF CB  1 
ATOM   1218 C CG1 . VAL E 1 36 ? 86.018  111.219 97.906  1.00 48.09  ? 36 VAL FF CG1 1 
ATOM   1219 C CG2 . VAL E 1 36 ? 88.443  110.674 97.675  1.00 41.47  ? 36 VAL FF CG2 1 
ATOM   1220 N N   . GLY E 1 37 ? 85.758  114.483 97.109  1.00 56.15  ? 37 GLY FF N   1 
ATOM   1221 C CA  . GLY E 1 37 ? 84.785  115.498 97.453  1.00 61.50  ? 37 GLY FF CA  1 
ATOM   1222 C C   . GLY E 1 37 ? 84.631  116.556 96.384  1.00 74.49  ? 37 GLY FF C   1 
ATOM   1223 O O   . GLY E 1 37 ? 84.228  116.253 95.258  1.00 81.43  ? 37 GLY FF O   1 
ATOM   1224 N N   . GLY E 1 38 ? 84.937  117.799 96.720  1.00 77.39  ? 38 GLY FF N   1 
ATOM   1225 C CA  . GLY E 1 38 ? 84.815  118.886 95.764  1.00 82.98  ? 38 GLY FF CA  1 
ATOM   1226 C C   . GLY E 1 38 ? 85.807  119.984 96.062  1.00 87.96  ? 38 GLY FF C   1 
ATOM   1227 O O   . GLY E 1 38 ? 86.038  120.340 97.222  1.00 86.27  ? 38 GLY FF O   1 
ATOM   1228 N N   . VAL E 1 39 ? 86.392  120.531 95.001  1.00 90.26  ? 39 VAL FF N   1 
ATOM   1229 C CA  . VAL E 1 39 ? 87.358  121.618 95.097  1.00 94.48  ? 39 VAL FF CA  1 
ATOM   1230 C C   . VAL E 1 39 ? 86.794  122.823 94.361  1.00 97.76  ? 39 VAL FF C   1 
ATOM   1231 O O   . VAL E 1 39 ? 86.474  122.736 93.170  1.00 93.80  ? 39 VAL FF O   1 
ATOM   1232 C CB  . VAL E 1 39 ? 88.727  121.215 94.519  1.00 91.47  ? 39 VAL FF CB  1 
ATOM   1233 C CG1 . VAL E 1 39 ? 89.581  122.445 94.271  1.00 90.96  ? 39 VAL FF CG1 1 
ATOM   1234 C CG2 . VAL E 1 39 ? 89.433  120.258 95.460  1.00 86.64  ? 39 VAL FF CG2 1 
ATOM   1235 N N   . VAL E 1 40 ? 86.669  123.940 95.071  1.00 101.84 ? 40 VAL FF N   1 
ATOM   1236 C CA  . VAL E 1 40 ? 86.199  125.197 94.501  1.00 102.74 ? 40 VAL FF CA  1 
ATOM   1237 C C   . VAL E 1 40 ? 87.305  126.225 94.673  1.00 105.52 ? 40 VAL FF C   1 
ATOM   1238 O O   . VAL E 1 40 ? 87.761  126.471 95.797  1.00 105.13 ? 40 VAL FF O   1 
ATOM   1239 C CB  . VAL E 1 40 ? 84.897  125.675 95.162  1.00 100.19 ? 40 VAL FF CB  1 
ATOM   1240 C CG1 . VAL E 1 40 ? 84.408  126.951 94.500  1.00 98.42  ? 40 VAL FF CG1 1 
ATOM   1241 C CG2 . VAL E 1 40 ? 83.835  124.591 95.085  1.00 97.85  ? 40 VAL FF CG2 1 
ATOM   1242 N N   . ILE E 1 41 ? 87.734  126.824 93.567  1.00 108.51 ? 41 ILE FF N   1 
ATOM   1243 C CA  . ILE E 1 41 ? 88.808  127.809 93.568  1.00 112.67 ? 41 ILE FF CA  1 
ATOM   1244 C C   . ILE E 1 41 ? 88.220  129.168 93.225  1.00 116.23 ? 41 ILE FF C   1 
ATOM   1245 O O   . ILE E 1 41 ? 87.529  129.318 92.209  1.00 115.97 ? 41 ILE FF O   1 
ATOM   1246 C CB  . ILE E 1 41 ? 89.918  127.423 92.577  1.00 112.79 ? 41 ILE FF CB  1 
ATOM   1247 C CG1 . ILE E 1 41 ? 90.357  125.978 92.807  1.00 107.76 ? 41 ILE FF CG1 1 
ATOM   1248 C CG2 . ILE E 1 41 ? 91.101  128.366 92.711  1.00 110.95 ? 41 ILE FF CG2 1 
ATOM   1249 C CD1 . ILE E 1 41 ? 91.326  125.469 91.770  1.00 104.16 ? 41 ILE FF CD1 1 
ATOM   1250 N N   . ALA E 1 42 ? 88.491  130.158 94.069  1.00 118.92 ? 42 ALA FF N   1 
ATOM   1251 C CA  . ALA E 1 42 ? 87.984  131.506 93.854  1.00 121.66 ? 42 ALA FF CA  1 
ATOM   1252 C C   . ALA E 1 42 ? 88.998  132.547 94.318  1.00 127.02 ? 42 ALA FF C   1 
ATOM   1253 O O   . ALA E 1 42 ? 89.953  132.229 95.025  1.00 129.60 ? 42 ALA FF O   1 
ATOM   1254 C CB  . ALA E 1 42 ? 86.660  131.694 94.576  1.00 117.58 ? 42 ALA FF CB  1 
ATOM   1255 O OXT . ALA E 1 42 ? 88.887  133.729 93.995  1.00 127.70 ? 42 ALA FF OXT 1 
ATOM   1256 N N   . GLY F 1 9  ? 78.550  116.530 119.422 1.00 75.58  ? 9  GLY AA N   1 
ATOM   1257 C CA  . GLY F 1 9  ? 79.309  115.746 120.379 1.00 77.59  ? 9  GLY AA CA  1 
ATOM   1258 C C   . GLY F 1 9  ? 80.455  114.983 119.747 1.00 77.76  ? 9  GLY AA C   1 
ATOM   1259 O O   . GLY F 1 9  ? 80.295  114.365 118.696 1.00 78.65  ? 9  GLY AA O   1 
ATOM   1260 N N   . TYR F 1 10 ? 81.617  115.024 120.391 1.00 74.83  ? 10 TYR AA N   1 
ATOM   1261 C CA  . TYR F 1 10 ? 82.815  114.357 119.904 1.00 70.87  ? 10 TYR AA CA  1 
ATOM   1262 C C   . TYR F 1 10 ? 83.071  113.111 120.738 1.00 65.85  ? 10 TYR AA C   1 
ATOM   1263 O O   . TYR F 1 10 ? 83.011  113.162 121.970 1.00 68.66  ? 10 TYR AA O   1 
ATOM   1264 C CB  . TYR F 1 10 ? 84.032  115.284 119.966 1.00 71.13  ? 10 TYR AA CB  1 
ATOM   1265 C CG  . TYR F 1 10 ? 83.906  116.552 119.151 1.00 81.03  ? 10 TYR AA CG  1 
ATOM   1266 C CD1 . TYR F 1 10 ? 82.953  116.672 118.150 1.00 83.11  ? 10 TYR AA CD1 1 
ATOM   1267 C CD2 . TYR F 1 10 ? 84.753  117.627 119.379 1.00 80.21  ? 10 TYR AA CD2 1 
ATOM   1268 C CE1 . TYR F 1 10 ? 82.839  117.831 117.408 1.00 84.09  ? 10 TYR AA CE1 1 
ATOM   1269 C CE2 . TYR F 1 10 ? 84.648  118.788 118.641 1.00 87.12  ? 10 TYR AA CE2 1 
ATOM   1270 C CZ  . TYR F 1 10 ? 83.690  118.884 117.655 1.00 91.17  ? 10 TYR AA CZ  1 
ATOM   1271 O OH  . TYR F 1 10 ? 83.583  120.039 116.917 1.00 91.09  ? 10 TYR AA OH  1 
ATOM   1272 N N   . GLU F 1 11 ? 83.351  111.998 120.069 1.00 61.80  ? 11 GLU AA N   1 
ATOM   1273 C CA  . GLU F 1 11 ? 83.685  110.739 120.728 1.00 57.88  ? 11 GLU AA CA  1 
ATOM   1274 C C   . GLU F 1 11 ? 85.022  110.266 120.171 1.00 52.72  ? 11 GLU AA C   1 
ATOM   1275 O O   . GLU F 1 11 ? 85.076  109.655 119.101 1.00 58.89  ? 11 GLU AA O   1 
ATOM   1276 C CB  . GLU F 1 11 ? 82.594  109.697 120.518 1.00 61.88  ? 11 GLU AA CB  1 
ATOM   1277 C CG  . GLU F 1 11 ? 82.591  108.600 121.564 1.00 65.71  ? 11 GLU AA CG  1 
ATOM   1278 C CD  . GLU F 1 11 ? 81.670  107.454 121.203 1.00 76.41  ? 11 GLU AA CD  1 
ATOM   1279 O OE1 . GLU F 1 11 ? 80.480  107.711 120.926 1.00 81.59  ? 11 GLU AA OE1 1 
ATOM   1280 O OE2 . GLU F 1 11 ? 82.135  106.295 121.200 1.00 75.54  ? 11 GLU AA OE2 1 
ATOM   1281 N N   . VAL F 1 12 ? 86.097  110.548 120.899 1.00 47.56  ? 12 VAL AA N   1 
ATOM   1282 C CA  . VAL F 1 12 ? 87.452  110.200 120.492 1.00 41.82  ? 12 VAL AA CA  1 
ATOM   1283 C C   . VAL F 1 12 ? 87.954  109.119 121.436 1.00 43.59  ? 12 VAL AA C   1 
ATOM   1284 O O   . VAL F 1 12 ? 87.938  109.302 122.658 1.00 54.65  ? 12 VAL AA O   1 
ATOM   1285 C CB  . VAL F 1 12 ? 88.375  111.426 120.517 1.00 38.02  ? 12 VAL AA CB  1 
ATOM   1286 C CG1 . VAL F 1 12 ? 89.733  111.084 119.949 1.00 36.81  ? 12 VAL AA CG1 1 
ATOM   1287 C CG2 . VAL F 1 12 ? 87.746  112.573 119.753 1.00 37.82  ? 12 VAL AA CG2 1 
ATOM   1288 N N   . HIS F 1 13 ? 88.395  107.991 120.884 1.00 39.40  ? 13 HIS AA N   1 
ATOM   1289 C CA  . HIS F 1 13 ? 88.912  106.927 121.730 1.00 42.52  ? 13 HIS AA CA  1 
ATOM   1290 C C   . HIS F 1 13 ? 89.919  106.082 120.967 1.00 39.69  ? 13 HIS AA C   1 
ATOM   1291 O O   . HIS F 1 13 ? 90.018  106.151 119.744 1.00 38.87  ? 13 HIS AA O   1 
ATOM   1292 C CB  . HIS F 1 13 ? 87.795  106.040 122.297 1.00 45.91  ? 13 HIS AA CB  1 
ATOM   1293 C CG  . HIS F 1 13 ? 86.736  105.668 121.307 1.00 46.41  ? 13 HIS AA CG  1 
ATOM   1294 N ND1 . HIS F 1 13 ? 86.505  104.364 120.927 1.00 43.92  ? 13 HIS AA ND1 1 
ATOM   1295 C CD2 . HIS F 1 13 ? 85.823  106.419 120.650 1.00 49.27  ? 13 HIS AA CD2 1 
ATOM   1296 C CE1 . HIS F 1 13 ? 85.508  104.331 120.062 1.00 48.42  ? 13 HIS AA CE1 1 
ATOM   1297 N NE2 . HIS F 1 13 ? 85.077  105.565 119.876 1.00 50.84  ? 13 HIS AA NE2 1 
ATOM   1298 N N   . HIS F 1 14 ? 90.691  105.302 121.724 1.00 39.43  ? 14 HIS AA N   1 
ATOM   1299 C CA  . HIS F 1 14 ? 91.642  104.330 121.186 1.00 36.41  ? 14 HIS AA CA  1 
ATOM   1300 C C   . HIS F 1 14 ? 92.666  104.992 120.263 1.00 34.91  ? 14 HIS AA C   1 
ATOM   1301 O O   . HIS F 1 14 ? 92.740  104.713 119.070 1.00 41.49  ? 14 HIS AA O   1 
ATOM   1302 C CB  . HIS F 1 14 ? 90.910  103.189 120.479 1.00 37.87  ? 14 HIS AA CB  1 
ATOM   1303 C CG  . HIS F 1 14 ? 90.114  102.328 121.406 1.00 43.65  ? 14 HIS AA CG  1 
ATOM   1304 N ND1 . HIS F 1 14 ? 88.791  102.577 121.699 1.00 45.90  ? 14 HIS AA ND1 1 
ATOM   1305 C CD2 . HIS F 1 14 ? 90.460  101.235 122.124 1.00 47.98  ? 14 HIS AA CD2 1 
ATOM   1306 C CE1 . HIS F 1 14 ? 88.352  101.666 122.548 1.00 53.85  ? 14 HIS AA CE1 1 
ATOM   1307 N NE2 . HIS F 1 14 ? 89.345  100.840 122.822 1.00 57.15  ? 14 HIS AA NE2 1 
ATOM   1308 N N   . GLN F 1 15 ? 93.470  105.875 120.844 1.00 31.09  ? 15 GLN AA N   1 
ATOM   1309 C CA  . GLN F 1 15 ? 94.535  106.556 120.124 1.00 25.82  ? 15 GLN AA CA  1 
ATOM   1310 C C   . GLN F 1 15 ? 95.877  106.177 120.727 1.00 27.11  ? 15 GLN AA C   1 
ATOM   1311 O O   . GLN F 1 15 ? 96.048  106.225 121.947 1.00 36.68  ? 15 GLN AA O   1 
ATOM   1312 C CB  . GLN F 1 15 ? 94.351  108.071 120.171 1.00 26.86  ? 15 GLN AA CB  1 
ATOM   1313 C CG  . GLN F 1 15 ? 93.666  108.637 118.954 1.00 36.02  ? 15 GLN AA CG  1 
ATOM   1314 C CD  . GLN F 1 15 ? 92.171  108.688 119.116 1.00 36.75  ? 15 GLN AA CD  1 
ATOM   1315 O OE1 . GLN F 1 15 ? 91.654  108.541 120.220 1.00 32.60  ? 15 GLN AA OE1 1 
ATOM   1316 N NE2 . GLN F 1 15 ? 91.463  108.891 118.015 1.00 36.88  ? 15 GLN AA NE2 1 
ATOM   1317 N N   . LYS F 1 16 ? 96.820  105.799 119.873 1.00 25.46  ? 16 LYS AA N   1 
ATOM   1318 C CA  . LYS F 1 16 ? 98.200  105.543 120.275 1.00 23.75  ? 16 LYS AA CA  1 
ATOM   1319 C C   . LYS F 1 16 ? 99.064  106.593 119.592 1.00 27.50  ? 16 LYS AA C   1 
ATOM   1320 O O   . LYS F 1 16 ? 99.376  106.471 118.404 1.00 37.91  ? 16 LYS AA O   1 
ATOM   1321 C CB  . LYS F 1 16 ? 98.636  104.133 119.905 1.00 23.54  ? 16 LYS AA CB  1 
ATOM   1322 C CG  . LYS F 1 16 ? 97.758  103.052 120.481 1.00 20.89  ? 16 LYS AA CG  1 
ATOM   1323 C CD  . LYS F 1 16 ? 98.348  101.690 120.221 1.00 22.06  ? 16 LYS AA CD  1 
ATOM   1324 C CE  . LYS F 1 16 ? 97.506  100.607 120.851 1.00 22.83  ? 16 LYS AA CE  1 
ATOM   1325 N NZ  . LYS F 1 16 ? 98.241  99.322  120.882 1.00 28.31  ? 16 LYS AA NZ  1 
ATOM   1326 N N   . LEU F 1 17 ? 99.451  107.620 120.338 1.00 23.96  ? 17 LEU AA N   1 
ATOM   1327 C CA  . LEU F 1 17 ? 100.162 108.764 119.790 1.00 25.08  ? 17 LEU AA CA  1 
ATOM   1328 C C   . LEU F 1 17 ? 101.565 108.824 120.371 1.00 25.06  ? 17 LEU AA C   1 
ATOM   1329 O O   . LEU F 1 17 ? 101.740 108.729 121.589 1.00 32.20  ? 17 LEU AA O   1 
ATOM   1330 C CB  . LEU F 1 17 ? 99.410  110.061 120.090 1.00 25.85  ? 17 LEU AA CB  1 
ATOM   1331 C CG  . LEU F 1 17 ? 99.811  111.292 119.281 1.00 28.96  ? 17 LEU AA CG  1 
ATOM   1332 C CD1 . LEU F 1 17 ? 98.572  112.036 118.834 1.00 37.70  ? 17 LEU AA CD1 1 
ATOM   1333 C CD2 . LEU F 1 17 ? 100.716 112.200 120.090 1.00 27.85  ? 17 LEU AA CD2 1 
ATOM   1334 N N   . VAL F 1 18 ? 102.558 108.974 119.502 1.00 24.89  ? 18 VAL AA N   1 
ATOM   1335 C CA  . VAL F 1 18 ? 103.936 109.221 119.904 1.00 26.58  ? 18 VAL AA CA  1 
ATOM   1336 C C   . VAL F 1 18 ? 104.376 110.531 119.273 1.00 29.85  ? 18 VAL AA C   1 
ATOM   1337 O O   . VAL F 1 18 ? 104.259 110.710 118.057 1.00 35.03  ? 18 VAL AA O   1 
ATOM   1338 C CB  . VAL F 1 18 ? 104.873 108.072 119.494 1.00 25.75  ? 18 VAL AA CB  1 
ATOM   1339 C CG1 . VAL F 1 18 ? 106.199 108.210 120.203 1.00 24.22  ? 18 VAL AA CG1 1 
ATOM   1340 C CG2 . VAL F 1 18 ? 104.242 106.736 119.818 1.00 24.63  ? 18 VAL AA CG2 1 
ATOM   1341 N N   . PHE F 1 19 ? 104.879 111.443 120.098 1.00 30.43  ? 19 PHE AA N   1 
ATOM   1342 C CA  . PHE F 1 19 ? 105.231 112.789 119.670 1.00 32.79  ? 19 PHE AA CA  1 
ATOM   1343 C C   . PHE F 1 19 ? 106.694 113.045 119.994 1.00 36.31  ? 19 PHE AA C   1 
ATOM   1344 O O   . PHE F 1 19 ? 107.081 113.046 121.166 1.00 43.04  ? 19 PHE AA O   1 
ATOM   1345 C CB  . PHE F 1 19 ? 104.336 113.821 120.357 1.00 36.08  ? 19 PHE AA CB  1 
ATOM   1346 C CG  . PHE F 1 19 ? 104.331 115.164 119.694 1.00 38.70  ? 19 PHE AA CG  1 
ATOM   1347 C CD1 . PHE F 1 19 ? 105.403 116.026 119.833 1.00 38.82  ? 19 PHE AA CD1 1 
ATOM   1348 C CD2 . PHE F 1 19 ? 103.246 115.573 118.945 1.00 41.78  ? 19 PHE AA CD2 1 
ATOM   1349 C CE1 . PHE F 1 19 ? 105.397 117.263 119.228 1.00 39.93  ? 19 PHE AA CE1 1 
ATOM   1350 C CE2 . PHE F 1 19 ? 103.234 116.810 118.339 1.00 44.10  ? 19 PHE AA CE2 1 
ATOM   1351 C CZ  . PHE F 1 19 ? 104.311 117.655 118.482 1.00 44.51  ? 19 PHE AA CZ  1 
ATOM   1352 N N   . PHE F 1 20 ? 107.499 113.264 118.961 1.00 35.86  ? 20 PHE AA N   1 
ATOM   1353 C CA  . PHE F 1 20 ? 108.898 113.638 119.113 1.00 37.59  ? 20 PHE AA CA  1 
ATOM   1354 C C   . PHE F 1 20 ? 109.054 115.107 118.755 1.00 45.25  ? 20 PHE AA C   1 
ATOM   1355 O O   . PHE F 1 20 ? 108.558 115.551 117.715 1.00 55.23  ? 20 PHE AA O   1 
ATOM   1356 C CB  . PHE F 1 20 ? 109.805 112.793 118.219 1.00 39.09  ? 20 PHE AA CB  1 
ATOM   1357 C CG  . PHE F 1 20 ? 109.875 111.349 118.607 1.00 38.58  ? 20 PHE AA CG  1 
ATOM   1358 C CD1 . PHE F 1 20 ? 108.985 110.435 118.080 1.00 36.65  ? 20 PHE AA CD1 1 
ATOM   1359 C CD2 . PHE F 1 20 ? 110.847 110.901 119.480 1.00 35.18  ? 20 PHE AA CD2 1 
ATOM   1360 C CE1 . PHE F 1 20 ? 109.056 109.106 118.426 1.00 33.87  ? 20 PHE AA CE1 1 
ATOM   1361 C CE2 . PHE F 1 20 ? 110.920 109.572 119.829 1.00 34.77  ? 20 PHE AA CE2 1 
ATOM   1362 C CZ  . PHE F 1 20 ? 110.023 108.674 119.302 1.00 31.87  ? 20 PHE AA CZ  1 
ATOM   1363 N N   . ALA F 1 21 ? 109.735 115.857 119.612 1.00 46.71  ? 21 ALA AA N   1 
ATOM   1364 C CA  . ALA F 1 21 ? 110.023 117.259 119.358 1.00 51.62  ? 21 ALA AA CA  1 
ATOM   1365 C C   . ALA F 1 21 ? 111.490 117.527 119.645 1.00 59.08  ? 21 ALA AA C   1 
ATOM   1366 O O   . ALA F 1 21 ? 112.036 117.036 120.636 1.00 64.50  ? 21 ALA AA O   1 
ATOM   1367 C CB  . ALA F 1 21 ? 109.141 118.176 120.208 1.00 47.68  ? 21 ALA AA CB  1 
ATOM   1368 N N   . GLU F 1 22 ? 112.126 118.297 118.772 1.00 62.23  ? 22 GLU AA N   1 
ATOM   1369 C CA  . GLU F 1 22 ? 113.525 118.654 118.956 1.00 69.45  ? 22 GLU AA CA  1 
ATOM   1370 C C   . GLU F 1 22 ? 113.733 120.144 118.749 1.00 74.34  ? 22 GLU AA C   1 
ATOM   1371 O O   . GLU F 1 22 ? 113.030 120.774 117.962 1.00 78.12  ? 22 GLU AA O   1 
ATOM   1372 C CB  . GLU F 1 22 ? 114.415 117.863 118.001 1.00 72.05  ? 22 GLU AA CB  1 
ATOM   1373 C CG  . GLU F 1 22 ? 114.736 116.466 118.482 1.00 71.84  ? 22 GLU AA CG  1 
ATOM   1374 C CD  . GLU F 1 22 ? 116.179 116.321 118.915 1.00 75.14  ? 22 GLU AA CD  1 
ATOM   1375 O OE1 . GLU F 1 22 ? 116.871 117.354 119.032 1.00 75.71  ? 22 GLU AA OE1 1 
ATOM   1376 O OE2 . GLU F 1 22 ? 116.623 115.175 119.139 1.00 74.25  ? 22 GLU AA OE2 1 
HETATM 1377 N N   . DAS F 1 23 ? 114.706 120.703 119.458 1.00 72.71  ? 23 DAS AA N   1 
HETATM 1378 C CA  . DAS F 1 23 ? 114.975 122.129 119.386 1.00 76.75  ? 23 DAS AA CA  1 
HETATM 1379 C C   . DAS F 1 23 ? 113.846 122.891 120.064 1.00 76.02  ? 23 DAS AA C   1 
HETATM 1380 O O   . DAS F 1 23 ? 113.861 123.079 121.279 1.00 76.84  ? 23 DAS AA O   1 
HETATM 1381 C CB  . DAS F 1 23 ? 116.310 122.450 120.057 1.00 83.90  ? 23 DAS AA CB  1 
HETATM 1382 C CG  . DAS F 1 23 ? 116.768 123.872 119.797 1.00 88.14  ? 23 DAS AA CG  1 
HETATM 1383 O OD1 . DAS F 1 23 ? 116.130 124.566 118.979 1.00 87.21  ? 23 DAS AA OD1 1 
HETATM 1384 O OD2 . DAS F 1 23 ? 117.768 124.296 120.412 1.00 86.54  ? 23 DAS AA OD2 1 
ATOM   1385 N N   . VAL F 1 24 ? 112.867 123.311 119.267 1.00 73.27  ? 24 VAL AA N   1 
ATOM   1386 C CA  . VAL F 1 24 ? 111.707 124.057 119.751 1.00 69.90  ? 24 VAL AA CA  1 
ATOM   1387 C C   . VAL F 1 24 ? 112.134 125.252 120.597 1.00 67.77  ? 24 VAL AA C   1 
ATOM   1388 O O   . VAL F 1 24 ? 111.934 125.271 121.808 1.00 70.39  ? 24 VAL AA O   1 
ATOM   1389 C CB  . VAL F 1 24 ? 110.750 123.147 120.539 1.00 64.79  ? 24 VAL AA CB  1 
ATOM   1390 C CG1 . VAL F 1 24 ? 109.415 123.835 120.737 1.00 56.42  ? 24 VAL AA CG1 1 
ATOM   1391 C CG2 . VAL F 1 24 ? 110.558 121.827 119.816 1.00 58.59  ? 24 VAL AA CG2 1 
ATOM   1392 N N   . GLY F 1 25 ? 112.730 126.252 119.952 1.00 65.16  ? 25 GLY AA N   1 
ATOM   1393 C CA  . GLY F 1 25 ? 113.227 127.425 120.645 1.00 63.72  ? 25 GLY AA CA  1 
ATOM   1394 C C   . GLY F 1 25 ? 112.270 128.594 120.501 1.00 65.69  ? 25 GLY AA C   1 
ATOM   1395 O O   . GLY F 1 25 ? 111.764 128.867 119.411 1.00 67.63  ? 25 GLY AA O   1 
ATOM   1396 N N   . SER F 1 26 ? 112.034 129.280 121.619 1.00 66.41  ? 26 SER AA N   1 
ATOM   1397 C CA  . SER F 1 26 ? 111.219 130.494 121.655 1.00 66.74  ? 26 SER AA CA  1 
ATOM   1398 C C   . SER F 1 26 ? 109.829 130.253 121.069 1.00 62.57  ? 26 SER AA C   1 
ATOM   1399 O O   . SER F 1 26 ? 109.314 131.047 120.280 1.00 59.58  ? 26 SER AA O   1 
ATOM   1400 C CB  . SER F 1 26 ? 111.926 131.644 120.936 1.00 65.12  ? 26 SER AA CB  1 
ATOM   1401 O OG  . SER F 1 26 ? 113.328 131.577 121.127 1.00 62.29  ? 26 SER AA OG  1 
ATOM   1402 N N   . ASN F 1 27 ? 109.218 129.141 121.464 1.00 58.74  ? 27 ASN AA N   1 
ATOM   1403 C CA  . ASN F 1 27 ? 107.870 128.826 121.012 1.00 53.96  ? 27 ASN AA CA  1 
ATOM   1404 C C   . ASN F 1 27 ? 106.870 129.760 121.681 1.00 54.07  ? 27 ASN AA C   1 
ATOM   1405 O O   . ASN F 1 27 ? 106.777 129.803 122.911 1.00 61.28  ? 27 ASN AA O   1 
ATOM   1406 C CB  . ASN F 1 27 ? 107.533 127.371 121.322 1.00 53.66  ? 27 ASN AA CB  1 
ATOM   1407 C CG  . ASN F 1 27 ? 106.041 127.116 121.363 1.00 48.69  ? 27 ASN AA CG  1 
ATOM   1408 O OD1 . ASN F 1 27 ? 105.333 127.353 120.387 1.00 46.96  ? 27 ASN AA OD1 1 
ATOM   1409 N ND2 . ASN F 1 27 ? 105.554 126.632 122.496 1.00 48.76  ? 27 ASN AA ND2 1 
ATOM   1410 N N   . LYS F 1 28 ? 106.127 130.511 120.873 1.00 49.39  ? 28 LYS AA N   1 
ATOM   1411 C CA  . LYS F 1 28 ? 105.079 131.388 121.371 1.00 50.70  ? 28 LYS AA CA  1 
ATOM   1412 C C   . LYS F 1 28 ? 103.683 130.872 121.062 1.00 50.43  ? 28 LYS AA C   1 
ATOM   1413 O O   . LYS F 1 28 ? 102.701 131.529 121.420 1.00 47.12  ? 28 LYS AA O   1 
ATOM   1414 C CB  . LYS F 1 28 ? 105.249 132.797 120.793 1.00 51.94  ? 28 LYS AA CB  1 
ATOM   1415 C CG  . LYS F 1 28 ? 106.633 133.379 120.999 1.00 54.88  ? 28 LYS AA CG  1 
ATOM   1416 C CD  . LYS F 1 28 ? 106.596 134.896 121.010 1.00 56.29  ? 28 LYS AA CD  1 
ATOM   1417 C CE  . LYS F 1 28 ? 107.997 135.480 121.064 1.00 61.55  ? 28 LYS AA CE  1 
ATOM   1418 N NZ  . LYS F 1 28 ? 109.042 134.419 121.064 1.00 55.99  ? 28 LYS AA NZ  1 
ATOM   1419 N N   . GLY F 1 29 ? 103.568 129.717 120.405 1.00 54.52  ? 29 GLY AA N   1 
ATOM   1420 C CA  . GLY F 1 29 ? 102.299 129.125 120.083 1.00 50.66  ? 29 GLY AA CA  1 
ATOM   1421 C C   . GLY F 1 29 ? 102.015 127.881 120.896 1.00 49.00  ? 29 GLY AA C   1 
ATOM   1422 O O   . GLY F 1 29 ? 102.638 127.621 121.933 1.00 48.69  ? 29 GLY AA O   1 
ATOM   1423 N N   . ALA F 1 30 ? 101.063 127.092 120.412 1.00 48.30  ? 30 ALA AA N   1 
ATOM   1424 C CA  . ALA F 1 30 ? 100.633 125.871 121.079 1.00 41.05  ? 30 ALA AA CA  1 
ATOM   1425 C C   . ALA F 1 30 ? 101.204 124.668 120.343 1.00 40.65  ? 30 ALA AA C   1 
ATOM   1426 O O   . ALA F 1 30 ? 101.000 124.523 119.134 1.00 43.98  ? 30 ALA AA O   1 
ATOM   1427 C CB  . ALA F 1 30 ? 99.109  125.789 121.137 1.00 35.72  ? 30 ALA AA CB  1 
ATOM   1428 N N   . ILE F 1 31 ? 101.913 123.813 121.070 1.00 38.51  ? 31 ILE AA N   1 
ATOM   1429 C CA  . ILE F 1 31 ? 102.422 122.552 120.546 1.00 37.05  ? 31 ILE AA CA  1 
ATOM   1430 C C   . ILE F 1 31 ? 101.717 121.439 121.303 1.00 40.18  ? 31 ILE AA C   1 
ATOM   1431 O O   . ILE F 1 31 ? 102.014 121.190 122.477 1.00 49.66  ? 31 ILE AA O   1 
ATOM   1432 C CB  . ILE F 1 31 ? 103.944 122.446 120.687 1.00 33.50  ? 31 ILE AA CB  1 
ATOM   1433 C CG1 . ILE F 1 31 ? 104.619 123.575 119.914 1.00 38.10  ? 31 ILE AA CG1 1 
ATOM   1434 C CG2 . ILE F 1 31 ? 104.429 121.091 120.202 1.00 30.82  ? 31 ILE AA CG2 1 
ATOM   1435 C CD1 . ILE F 1 31 ? 106.085 123.367 119.699 1.00 42.08  ? 31 ILE AA CD1 1 
ATOM   1436 N N   . ILE F 1 32 ? 100.782 120.768 120.639 1.00 37.80  ? 32 ILE AA N   1 
ATOM   1437 C CA  . ILE F 1 32 ? 99.910  119.791 121.277 1.00 42.84  ? 32 ILE AA CA  1 
ATOM   1438 C C   . ILE F 1 32 ? 100.067 118.453 120.574 1.00 42.30  ? 32 ILE AA C   1 
ATOM   1439 O O   . ILE F 1 32 ? 100.137 118.392 119.343 1.00 45.16  ? 32 ILE AA O   1 
ATOM   1440 C CB  . ILE F 1 32 ? 98.438  120.250 121.258 1.00 44.85  ? 32 ILE AA CB  1 
ATOM   1441 C CG1 . ILE F 1 32 ? 98.324  121.690 121.756 1.00 42.64  ? 32 ILE AA CG1 1 
ATOM   1442 C CG2 . ILE F 1 32 ? 97.589  119.337 122.115 1.00 48.55  ? 32 ILE AA CG2 1 
ATOM   1443 C CD1 . ILE F 1 32 ? 97.330  122.523 120.987 1.00 40.67  ? 32 ILE AA CD1 1 
ATOM   1444 N N   . GLY F 1 33 ? 100.136 117.383 121.358 1.00 44.70  ? 33 GLY AA N   1 
ATOM   1445 C CA  . GLY F 1 33 ? 100.177 116.048 120.797 1.00 40.70  ? 33 GLY AA CA  1 
ATOM   1446 C C   . GLY F 1 33 ? 98.823  115.615 120.278 1.00 40.23  ? 33 GLY AA C   1 
ATOM   1447 O O   . GLY F 1 33 ? 98.667  115.335 119.088 1.00 43.73  ? 33 GLY AA O   1 
ATOM   1448 N N   . LEU F 1 34 ? 97.834  115.553 121.165 1.00 41.37  ? 34 LEU AA N   1 
ATOM   1449 C CA  . LEU F 1 34 ? 96.458  115.256 120.792 1.00 41.56  ? 34 LEU AA CA  1 
ATOM   1450 C C   . LEU F 1 34 ? 95.572  116.349 121.362 1.00 43.59  ? 34 LEU AA C   1 
ATOM   1451 O O   . LEU F 1 34 ? 95.578  116.584 122.573 1.00 52.62  ? 34 LEU AA O   1 
ATOM   1452 C CB  . LEU F 1 34 ? 96.022  113.886 121.316 1.00 42.98  ? 34 LEU AA CB  1 
ATOM   1453 C CG  . LEU F 1 34 ? 94.755  113.291 120.701 1.00 39.98  ? 34 LEU AA CG  1 
ATOM   1454 C CD1 . LEU F 1 34 ? 94.991  111.841 120.321 1.00 33.09  ? 34 LEU AA CD1 1 
ATOM   1455 C CD2 . LEU F 1 34 ? 93.571  113.416 121.639 1.00 40.03  ? 34 LEU AA CD2 1 
ATOM   1456 N N   . MET F 1 35 ? 94.813  117.014 120.499 1.00 38.84  ? 35 MET AA N   1 
ATOM   1457 C CA  . MET F 1 35 ? 93.946  118.108 120.904 1.00 44.10  ? 35 MET AA CA  1 
ATOM   1458 C C   . MET F 1 35 ? 92.524  117.816 120.453 1.00 48.26  ? 35 MET AA C   1 
ATOM   1459 O O   . MET F 1 35 ? 92.294  117.506 119.281 1.00 57.64  ? 35 MET AA O   1 
ATOM   1460 C CB  . MET F 1 35 ? 94.425  119.435 120.316 1.00 46.59  ? 35 MET AA CB  1 
ATOM   1461 C CG  . MET F 1 35 ? 93.367  120.515 120.306 1.00 51.67  ? 35 MET AA CG  1 
ATOM   1462 S SD  . MET F 1 35 ? 93.444  121.594 121.737 1.00 73.51  ? 35 MET AA SD  1 
ATOM   1463 C CE  . MET F 1 35 ? 91.852  122.399 121.639 1.00 71.03  ? 35 MET AA CE  1 
ATOM   1464 N N   . VAL F 1 36 ? 91.578  117.911 121.380 1.00 48.97  ? 36 VAL AA N   1 
ATOM   1465 C CA  . VAL F 1 36 ? 90.159  117.760 121.086 1.00 50.21  ? 36 VAL AA CA  1 
ATOM   1466 C C   . VAL F 1 36 ? 89.456  119.021 121.561 1.00 56.88  ? 36 VAL AA C   1 
ATOM   1467 O O   . VAL F 1 36 ? 89.605  119.419 122.723 1.00 64.00  ? 36 VAL AA O   1 
ATOM   1468 C CB  . VAL F 1 36 ? 89.561  116.514 121.753 1.00 46.62  ? 36 VAL AA CB  1 
ATOM   1469 C CG1 . VAL F 1 36 ? 88.071  116.436 121.480 1.00 48.09  ? 36 VAL AA CG1 1 
ATOM   1470 C CG2 . VAL F 1 36 ? 90.263  115.262 121.262 1.00 41.47  ? 36 VAL AA CG2 1 
ATOM   1471 N N   . GLY F 1 37 ? 88.695  119.647 120.671 1.00 56.15  ? 37 GLY AA N   1 
ATOM   1472 C CA  . GLY F 1 37 ? 88.027  120.886 121.007 1.00 61.50  ? 37 GLY AA CA  1 
ATOM   1473 C C   . GLY F 1 37 ? 88.165  121.943 119.933 1.00 74.49  ? 37 GLY AA C   1 
ATOM   1474 O O   . GLY F 1 37 ? 87.700  121.753 118.807 1.00 81.43  ? 37 GLY AA O   1 
ATOM   1475 N N   . GLY F 1 38 ? 88.791  123.061 120.266 1.00 77.39  ? 38 GLY AA N   1 
ATOM   1476 C CA  . GLY F 1 38 ? 88.967  124.136 119.307 1.00 82.98  ? 38 GLY AA CA  1 
ATOM   1477 C C   . GLY F 1 38 ? 90.215  124.931 119.606 1.00 87.96  ? 38 GLY AA C   1 
ATOM   1478 O O   . GLY F 1 38 ? 90.529  125.217 120.765 1.00 86.27  ? 38 GLY AA O   1 
ATOM   1479 N N   . VAL F 1 39 ? 90.928  125.297 118.545 1.00 90.26  ? 39 VAL AA N   1 
ATOM   1480 C CA  . VAL F 1 39 ? 92.149  126.086 118.642 1.00 94.48  ? 39 VAL AA CA  1 
ATOM   1481 C C   . VAL F 1 39 ? 91.930  127.395 117.899 1.00 97.76  ? 39 VAL AA C   1 
ATOM   1482 O O   . VAL F 1 39 ? 91.602  127.391 116.707 1.00 93.80  ? 39 VAL AA O   1 
ATOM   1483 C CB  . VAL F 1 39 ? 93.363  125.330 118.071 1.00 91.47  ? 39 VAL AA CB  1 
ATOM   1484 C CG1 . VAL F 1 39 ? 94.515  126.286 117.822 1.00 90.96  ? 39 VAL AA CG1 1 
ATOM   1485 C CG2 . VAL F 1 39 ? 93.785  124.223 119.018 1.00 86.64  ? 39 VAL AA CG2 1 
ATOM   1486 N N   . VAL F 1 40 ? 92.106  128.509 118.604 1.00 101.84 ? 40 VAL AA N   1 
ATOM   1487 C CA  . VAL F 1 40 ? 91.990  129.842 118.028 1.00 102.74 ? 40 VAL AA CA  1 
ATOM   1488 C C   . VAL F 1 40 ? 93.330  130.538 118.202 1.00 105.52 ? 40 VAL AA C   1 
ATOM   1489 O O   . VAL F 1 40 ? 93.831  130.659 119.326 1.00 105.13 ? 40 VAL AA O   1 
ATOM   1490 C CB  . VAL F 1 40 ? 90.861  130.654 118.681 1.00 100.19 ? 40 VAL AA CB  1 
ATOM   1491 C CG1 . VAL F 1 40 ? 90.733  132.011 118.013 1.00 98.42  ? 40 VAL AA CG1 1 
ATOM   1492 C CG2 . VAL F 1 40 ? 89.549  129.892 118.603 1.00 97.85  ? 40 VAL AA CG2 1 
ATOM   1493 N N   . ILE F 1 41 ? 93.907  130.996 117.095 1.00 108.51 ? 41 ILE AA N   1 
ATOM   1494 C CA  . ILE F 1 41 ? 95.205  131.658 117.098 1.00 112.67 ? 41 ILE AA CA  1 
ATOM   1495 C C   . ILE F 1 41 ? 95.003  133.124 116.747 1.00 116.23 ? 41 ILE AA C   1 
ATOM   1496 O O   . ILE F 1 41 ? 94.380  133.448 115.728 1.00 115.97 ? 41 ILE AA O   1 
ATOM   1497 C CB  . ILE F 1 41 ? 96.175  130.986 116.113 1.00 112.79 ? 41 ILE AA CB  1 
ATOM   1498 C CG1 . ILE F 1 41 ? 96.212  129.477 116.350 1.00 107.76 ? 41 ILE AA CG1 1 
ATOM   1499 C CG2 . ILE F 1 41 ? 97.566  131.579 116.249 1.00 110.95 ? 41 ILE AA CG2 1 
ATOM   1500 C CD1 . ILE F 1 41 ? 97.013  128.723 115.319 1.00 104.16 ? 41 ILE AA CD1 1 
ATOM   1501 N N   . ALA F 1 42 ? 95.525  134.009 117.589 1.00 118.92 ? 42 ALA AA N   1 
ATOM   1502 C CA  . ALA F 1 42 ? 95.397  135.443 117.368 1.00 121.66 ? 42 ALA AA CA  1 
ATOM   1503 C C   . ALA F 1 42 ? 96.650  136.177 117.832 1.00 127.02 ? 42 ALA AA C   1 
ATOM   1504 O O   . ALA F 1 42 ? 97.484  135.619 118.545 1.00 129.60 ? 42 ALA AA O   1 
ATOM   1505 C CB  . ALA F 1 42 ? 94.169  135.981 118.083 1.00 117.58 ? 42 ALA AA CB  1 
ATOM   1506 O OXT . ALA F 1 42 ? 96.861  137.345 117.504 1.00 127.70 ? 42 ALA AA OXT 1 
ATOM   1507 N N   . GLY G 1 9  ? 134.196 96.715  117.118 1.00 75.58  ? 9  GLY A  N   1 
ATOM   1508 C CA  . GLY G 1 9  ? 133.415 97.479  118.072 1.00 77.59  ? 9  GLY A  CA  1 
ATOM   1509 C C   . GLY G 1 9  ? 132.249 98.209  117.438 1.00 77.76  ? 9  GLY A  C   1 
ATOM   1510 O O   . GLY G 1 9  ? 132.393 98.829  116.386 1.00 78.65  ? 9  GLY A  O   1 
ATOM   1511 N N   . TYR G 1 10 ? 131.088 98.136  118.081 1.00 74.83  ? 10 TYR A  N   1 
ATOM   1512 C CA  . TYR G 1 10 ? 129.871 98.769  117.591 1.00 70.87  ? 10 TYR A  CA  1 
ATOM   1513 C C   . TYR G 1 10 ? 129.580 100.008 118.423 1.00 65.85  ? 10 TYR A  C   1 
ATOM   1514 O O   . TYR G 1 10 ? 129.640 99.961  119.655 1.00 68.66  ? 10 TYR A  O   1 
ATOM   1515 C CB  . TYR G 1 10 ? 128.681 97.809  117.653 1.00 71.13  ? 10 TYR A  CB  1 
ATOM   1516 C CG  . TYR G 1 10 ? 128.843 96.543  116.841 1.00 81.03  ? 10 TYR A  CG  1 
ATOM   1517 C CD1 . TYR G 1 10 ? 129.801 96.448  115.840 1.00 83.11  ? 10 TYR A  CD1 1 
ATOM   1518 C CD2 . TYR G 1 10 ? 128.027 95.445  117.069 1.00 80.21  ? 10 TYR A  CD2 1 
ATOM   1519 C CE1 . TYR G 1 10 ? 129.948 95.292  115.100 1.00 84.09  ? 10 TYR A  CE1 1 
ATOM   1520 C CE2 . TYR G 1 10 ? 128.165 94.286  116.333 1.00 87.12  ? 10 TYR A  CE2 1 
ATOM   1521 C CZ  . TYR G 1 10 ? 129.126 94.216  115.349 1.00 91.17  ? 10 TYR A  CZ  1 
ATOM   1522 O OH  . TYR G 1 10 ? 129.266 93.063  114.612 1.00 91.09  ? 10 TYR A  OH  1 
ATOM   1523 N N   . GLU G 1 11 ? 129.271 101.112 117.751 1.00 61.80  ? 11 GLU A  N   1 
ATOM   1524 C CA  . GLU G 1 11 ? 128.900 102.362 118.408 1.00 57.88  ? 11 GLU A  CA  1 
ATOM   1525 C C   . GLU G 1 11 ? 127.551 102.797 117.849 1.00 52.72  ? 11 GLU A  C   1 
ATOM   1526 O O   . GLU G 1 11 ? 127.481 103.405 116.777 1.00 58.89  ? 11 GLU A  O   1 
ATOM   1527 C CB  . GLU G 1 11 ? 129.962 103.434 118.198 1.00 61.88  ? 11 GLU A  CB  1 
ATOM   1528 C CG  . GLU G 1 11 ? 129.934 104.533 119.242 1.00 65.71  ? 11 GLU A  CG  1 
ATOM   1529 C CD  . GLU G 1 11 ? 130.823 105.703 118.880 1.00 76.41  ? 11 GLU A  CD  1 
ATOM   1530 O OE1 . GLU G 1 11 ? 132.020 105.479 118.604 1.00 81.59  ? 11 GLU A  OE1 1 
ATOM   1531 O OE2 . GLU G 1 11 ? 130.326 106.848 118.875 1.00 75.54  ? 11 GLU A  OE2 1 
ATOM   1532 N N   . VAL G 1 12 ? 126.484 102.486 118.575 1.00 47.56  ? 12 VAL A  N   1 
ATOM   1533 C CA  . VAL G 1 12 ? 125.120 102.796 118.167 1.00 41.82  ? 12 VAL A  CA  1 
ATOM   1534 C C   . VAL G 1 12 ? 124.587 103.864 119.108 1.00 43.59  ? 12 VAL A  C   1 
ATOM   1535 O O   . VAL G 1 12 ? 124.607 103.683 120.331 1.00 54.65  ? 12 VAL A  O   1 
ATOM   1536 C CB  . VAL G 1 12 ? 124.231 101.544 118.192 1.00 38.02  ? 12 VAL A  CB  1 
ATOM   1537 C CG1 . VAL G 1 12 ? 122.865 101.848 117.622 1.00 36.81  ? 12 VAL A  CG1 1 
ATOM   1538 C CG2 . VAL G 1 12 ? 124.894 100.414 117.431 1.00 37.82  ? 12 VAL A  CG2 1 
ATOM   1539 N N   . HIS G 1 13 ? 124.116 104.979 118.553 1.00 39.40  ? 13 HIS A  N   1 
ATOM   1540 C CA  . HIS G 1 13 ? 123.567 106.029 119.397 1.00 42.52  ? 13 HIS A  CA  1 
ATOM   1541 C C   . HIS G 1 13 ? 122.538 106.845 118.632 1.00 39.69  ? 13 HIS A  C   1 
ATOM   1542 O O   . HIS G 1 13 ? 122.443 106.770 117.409 1.00 38.87  ? 13 HIS A  O   1 
ATOM   1543 C CB  . HIS G 1 13 ? 124.659 106.948 119.964 1.00 45.91  ? 13 HIS A  CB  1 
ATOM   1544 C CG  . HIS G 1 13 ? 125.708 107.348 118.975 1.00 46.41  ? 13 HIS A  CG  1 
ATOM   1545 N ND1 . HIS G 1 13 ? 125.904 108.657 118.593 1.00 43.92  ? 13 HIS A  ND1 1 
ATOM   1546 C CD2 . HIS G 1 13 ? 126.643 106.621 118.320 1.00 49.27  ? 13 HIS A  CD2 1 
ATOM   1547 C CE1 . HIS G 1 13 ? 126.900 108.716 117.729 1.00 48.42  ? 13 HIS A  CE1 1 
ATOM   1548 N NE2 . HIS G 1 13 ? 127.366 107.494 117.545 1.00 50.84  ? 13 HIS A  NE2 1 
ATOM   1549 N N   . HIS G 1 14 ? 121.745 107.604 119.386 1.00 39.43  ? 14 HIS A  N   1 
ATOM   1550 C CA  . HIS G 1 14 ? 120.767 108.548 118.846 1.00 36.41  ? 14 HIS A  CA  1 
ATOM   1551 C C   . HIS G 1 14 ? 119.764 107.856 117.923 1.00 34.91  ? 14 HIS A  C   1 
ATOM   1552 O O   . HIS G 1 14 ? 119.683 108.130 116.729 1.00 41.49  ? 14 HIS A  O   1 
ATOM   1553 C CB  . HIS G 1 14 ? 121.468 109.708 118.138 1.00 37.87  ? 14 HIS A  CB  1 
ATOM   1554 C CG  . HIS G 1 14 ? 122.239 110.592 119.064 1.00 43.65  ? 14 HIS A  CG  1 
ATOM   1555 N ND1 . HIS G 1 14 ? 123.568 110.380 119.359 1.00 45.90  ? 14 HIS A  ND1 1 
ATOM   1556 C CD2 . HIS G 1 14 ? 121.862 111.677 119.779 1.00 47.98  ? 14 HIS A  CD2 1 
ATOM   1557 C CE1 . HIS G 1 14 ? 123.980 111.305 120.207 1.00 53.85  ? 14 HIS A  CE1 1 
ATOM   1558 N NE2 . HIS G 1 14 ? 122.964 112.103 120.479 1.00 57.15  ? 14 HIS A  NE2 1 
ATOM   1559 N N   . GLN G 1 15 ? 118.984 106.952 118.505 1.00 31.09  ? 15 GLN A  N   1 
ATOM   1560 C CA  . GLN G 1 15 ? 117.939 106.240 117.785 1.00 25.82  ? 15 GLN A  CA  1 
ATOM   1561 C C   . GLN G 1 15 ? 116.586 106.583 118.384 1.00 27.11  ? 15 GLN A  C   1 
ATOM   1562 O O   . GLN G 1 15 ? 116.415 106.532 119.605 1.00 36.68  ? 15 GLN A  O   1 
ATOM   1563 C CB  . GLN G 1 15 ? 118.165 104.731 117.834 1.00 26.86  ? 15 GLN A  CB  1 
ATOM   1564 C CG  . GLN G 1 15 ? 118.866 104.182 116.618 1.00 36.02  ? 15 GLN A  CG  1 
ATOM   1565 C CD  . GLN G 1 15 ? 120.362 104.173 116.782 1.00 36.75  ? 15 GLN A  CD  1 
ATOM   1566 O OE1 . GLN G 1 15 ? 120.873 104.337 117.887 1.00 32.60  ? 15 GLN A  OE1 1 
ATOM   1567 N NE2 . GLN G 1 15 ? 121.077 103.989 115.683 1.00 36.88  ? 15 GLN A  NE2 1 
ATOM   1568 N N   . LYS G 1 16 ? 115.633 106.933 117.529 1.00 25.46  ? 16 LYS A  N   1 
ATOM   1569 C CA  . LYS G 1 16 ? 114.247 107.151 117.930 1.00 23.75  ? 16 LYS A  CA  1 
ATOM   1570 C C   . LYS G 1 16 ? 113.413 106.077 117.247 1.00 27.50  ? 16 LYS A  C   1 
ATOM   1571 O O   . LYS G 1 16 ? 113.099 106.187 116.059 1.00 37.91  ? 16 LYS A  O   1 
ATOM   1572 C CB  . LYS G 1 16 ? 113.772 108.548 117.556 1.00 23.54  ? 16 LYS A  CB  1 
ATOM   1573 C CG  . LYS G 1 16 ? 114.619 109.653 118.132 1.00 20.89  ? 16 LYS A  CG  1 
ATOM   1574 C CD  . LYS G 1 16 ? 113.992 110.998 117.869 1.00 22.06  ? 16 LYS A  CD  1 
ATOM   1575 C CE  . LYS G 1 16 ? 114.802 112.105 118.498 1.00 22.83  ? 16 LYS A  CE  1 
ATOM   1576 N NZ  . LYS G 1 16 ? 114.031 113.370 118.525 1.00 28.31  ? 16 LYS A  NZ  1 
ATOM   1577 N N   . LEU G 1 17 ? 113.054 105.040 117.994 1.00 23.96  ? 17 LEU A  N   1 
ATOM   1578 C CA  . LEU G 1 17 ? 112.376 103.876 117.447 1.00 25.08  ? 17 LEU A  CA  1 
ATOM   1579 C C   . LEU G 1 17 ? 110.975 103.778 118.027 1.00 25.06  ? 17 LEU A  C   1 
ATOM   1580 O O   . LEU G 1 17 ? 110.795 103.870 119.244 1.00 32.20  ? 17 LEU A  O   1 
ATOM   1581 C CB  . LEU G 1 17 ? 113.163 102.601 117.750 1.00 25.85  ? 17 LEU A  CB  1 
ATOM   1582 C CG  . LEU G 1 17 ? 112.798 101.358 116.943 1.00 28.96  ? 17 LEU A  CG  1 
ATOM   1583 C CD1 . LEU G 1 17 ? 114.058 100.648 116.499 1.00 37.70  ? 17 LEU A  CD1 1 
ATOM   1584 C CD2 . LEU G 1 17 ? 111.918 100.426 117.752 1.00 27.85  ? 17 LEU A  CD2 1 
ATOM   1585 N N   . VAL G 1 18 ? 109.987 103.599 117.156 1.00 24.89  ? 18 VAL A  N   1 
ATOM   1586 C CA  . VAL G 1 18 ? 108.616 103.314 117.558 1.00 26.58  ? 18 VAL A  CA  1 
ATOM   1587 C C   . VAL G 1 18 ? 108.213 101.991 116.929 1.00 29.85  ? 18 VAL A  C   1 
ATOM   1588 O O   . VAL G 1 18 ? 108.337 101.813 115.713 1.00 35.03  ? 18 VAL A  O   1 
ATOM   1589 C CB  . VAL G 1 18 ? 107.648 104.436 117.145 1.00 25.75  ? 18 VAL A  CB  1 
ATOM   1590 C CG1 . VAL G 1 18 ? 106.325 104.262 117.853 1.00 24.22  ? 18 VAL A  CG1 1 
ATOM   1591 C CG2 . VAL G 1 18 ? 108.241 105.789 117.467 1.00 24.63  ? 18 VAL A  CG2 1 
ATOM   1592 N N   . PHE G 1 19 ? 107.735 101.067 117.755 1.00 30.43  ? 19 PHE A  N   1 
ATOM   1593 C CA  . PHE G 1 19 ? 107.421 99.710  117.328 1.00 32.79  ? 19 PHE A  CA  1 
ATOM   1594 C C   . PHE G 1 19 ? 105.966 99.415  117.651 1.00 36.31  ? 19 PHE A  C   1 
ATOM   1595 O O   . PHE G 1 19 ? 105.578 99.404  118.822 1.00 43.04  ? 19 PHE A  O   1 
ATOM   1596 C CB  . PHE G 1 19 ? 108.344 98.705  118.018 1.00 36.08  ? 19 PHE A  CB  1 
ATOM   1597 C CG  . PHE G 1 19 ? 108.387 97.361  117.358 1.00 38.70  ? 19 PHE A  CG  1 
ATOM   1598 C CD1 . PHE G 1 19 ? 107.340 96.470  117.496 1.00 38.82  ? 19 PHE A  CD1 1 
ATOM   1599 C CD2 . PHE G 1 19 ? 109.484 96.982  116.610 1.00 41.78  ? 19 PHE A  CD2 1 
ATOM   1600 C CE1 . PHE G 1 19 ? 107.381 95.233  116.894 1.00 39.93  ? 19 PHE A  CE1 1 
ATOM   1601 C CE2 . PHE G 1 19 ? 109.531 95.745  116.006 1.00 44.10  ? 19 PHE A  CE2 1 
ATOM   1602 C CZ  . PHE G 1 19 ? 108.478 94.870  116.149 1.00 44.51  ? 19 PHE A  CZ  1 
ATOM   1603 N N   . PHE G 1 20 ? 105.168 99.172  116.618 1.00 35.86  ? 20 PHE A  N   1 
ATOM   1604 C CA  . PHE G 1 20 ? 103.780 98.758  116.768 1.00 37.59  ? 20 PHE A  CA  1 
ATOM   1605 C C   . PHE G 1 20 ? 103.666 97.285  116.412 1.00 45.25  ? 20 PHE A  C   1 
ATOM   1606 O O   . PHE G 1 20 ? 104.175 96.854  115.374 1.00 55.23  ? 20 PHE A  O   1 
ATOM   1607 C CB  . PHE G 1 20 ? 102.851 99.576  115.872 1.00 39.09  ? 20 PHE A  CB  1 
ATOM   1608 C CG  . PHE G 1 20 ? 102.740 101.019 116.258 1.00 38.58  ? 20 PHE A  CG  1 
ATOM   1609 C CD1 . PHE G 1 20 ? 103.605 101.956 115.730 1.00 36.65  ? 20 PHE A  CD1 1 
ATOM   1610 C CD2 . PHE G 1 20 ? 101.755 101.441 117.128 1.00 35.18  ? 20 PHE A  CD2 1 
ATOM   1611 C CE1 . PHE G 1 20 ? 103.497 103.283 116.074 1.00 33.87  ? 20 PHE A  CE1 1 
ATOM   1612 C CE2 . PHE G 1 20 ? 101.644 102.768 117.475 1.00 34.77  ? 20 PHE A  CE2 1 
ATOM   1613 C CZ  . PHE G 1 20 ? 102.517 103.690 116.947 1.00 31.87  ? 20 PHE A  CZ  1 
ATOM   1614 N N   . ALA G 1 21 ? 103.005 96.518  117.270 1.00 46.71  ? 21 ALA A  N   1 
ATOM   1615 C CA  . ALA G 1 21 ? 102.756 95.108  117.018 1.00 51.62  ? 21 ALA A  CA  1 
ATOM   1616 C C   . ALA G 1 21 ? 101.297 94.800  117.304 1.00 59.08  ? 21 ALA A  C   1 
ATOM   1617 O O   . ALA G 1 21 ? 100.736 95.277  118.294 1.00 64.50  ? 21 ALA A  O   1 
ATOM   1618 C CB  . ALA G 1 21 ? 103.662 94.217  117.870 1.00 47.68  ? 21 ALA A  CB  1 
ATOM   1619 N N   . GLU G 1 22 ? 100.683 94.011  116.432 1.00 62.23  ? 22 GLU A  N   1 
ATOM   1620 C CA  . GLU G 1 22 ? 99.295  93.615  116.614 1.00 69.45  ? 22 GLU A  CA  1 
ATOM   1621 C C   . GLU G 1 22 ? 99.129  92.119  116.410 1.00 74.34  ? 22 GLU A  C   1 
ATOM   1622 O O   . GLU G 1 22 ? 99.850  91.508  115.625 1.00 78.12  ? 22 GLU A  O   1 
ATOM   1623 C CB  . GLU G 1 22 ? 98.385  94.380  115.658 1.00 72.05  ? 22 GLU A  CB  1 
ATOM   1624 C CG  . GLU G 1 22 ? 98.024  95.768  116.136 1.00 71.84  ? 22 GLU A  CG  1 
ATOM   1625 C CD  . GLU G 1 22 ? 96.577  95.873  116.567 1.00 75.14  ? 22 GLU A  CD  1 
ATOM   1626 O OE1 . GLU G 1 22 ? 95.914  94.822  116.684 1.00 75.71  ? 22 GLU A  OE1 1 
ATOM   1627 O OE2 . GLU G 1 22 ? 96.101  97.007  116.788 1.00 74.25  ? 22 GLU A  OE2 1 
HETATM 1628 N N   . DAS G 1 23 ? 98.171  91.535  117.119 1.00 72.71  ? 23 DAS A  N   1 
HETATM 1629 C CA  . DAS G 1 23 ? 97.942  90.102  117.048 1.00 76.75  ? 23 DAS A  CA  1 
HETATM 1630 C C   . DAS G 1 23 ? 99.091  89.373  117.730 1.00 76.02  ? 23 DAS A  C   1 
HETATM 1631 O O   . DAS G 1 23 ? 99.079  89.186  118.945 1.00 76.84  ? 23 DAS A  O   1 
HETATM 1632 C CB  . DAS G 1 23 ? 96.615  89.745  117.718 1.00 83.90  ? 23 DAS A  CB  1 
HETATM 1633 C CG  . DAS G 1 23 ? 96.198  88.310  117.461 1.00 88.14  ? 23 DAS A  CG  1 
HETATM 1634 O OD1 . DAS G 1 23 ? 96.856  87.633  116.644 1.00 87.21  ? 23 DAS A  OD1 1 
HETATM 1635 O OD2 . DAS G 1 23 ? 95.209  87.859  118.076 1.00 86.54  ? 23 DAS A  OD2 1 
ATOM   1636 N N   . VAL G 1 24 ? 100.082 88.979  116.935 1.00 73.27  ? 24 VAL A  N   1 
ATOM   1637 C CA  . VAL G 1 24 ? 101.262 88.267  117.420 1.00 69.90  ? 24 VAL A  CA  1 
ATOM   1638 C C   . VAL G 1 24 ? 100.867 87.061  118.268 1.00 67.77  ? 24 VAL A  C   1 
ATOM   1639 O O   . VAL G 1 24 ? 101.066 87.050  119.479 1.00 70.39  ? 24 VAL A  O   1 
ATOM   1640 C CB  . VAL G 1 24 ? 102.193 89.205  118.208 1.00 64.79  ? 24 VAL A  CB  1 
ATOM   1641 C CG1 . VAL G 1 24 ? 103.546 88.555  118.409 1.00 56.42  ? 24 VAL A  CG1 1 
ATOM   1642 C CG2 . VAL G 1 24 ? 102.348 90.527  117.484 1.00 58.59  ? 24 VAL A  CG2 1 
ATOM   1643 N N   . GLY G 1 25 ? 100.300 86.044  117.625 1.00 65.16  ? 25 GLY A  N   1 
ATOM   1644 C CA  . GLY G 1 25 ? 99.836  84.858  118.318 1.00 63.72  ? 25 GLY A  CA  1 
ATOM   1645 C C   . GLY G 1 25 ? 100.824 83.716  118.178 1.00 65.69  ? 25 GLY A  C   1 
ATOM   1646 O O   . GLY G 1 25 ? 101.340 83.456  117.089 1.00 67.63  ? 25 GLY A  O   1 
ATOM   1647 N N   . SER G 1 26 ? 101.078 83.040  119.298 1.00 66.41  ? 26 SER A  N   1 
ATOM   1648 C CA  . SER G 1 26 ? 101.927 81.849  119.336 1.00 66.74  ? 26 SER A  CA  1 
ATOM   1649 C C   . SER G 1 26 ? 103.310 82.127  118.752 1.00 62.57  ? 26 SER A  C   1 
ATOM   1650 O O   . SER G 1 26 ? 103.848 81.347  117.964 1.00 59.58  ? 26 SER A  O   1 
ATOM   1651 C CB  . SER G 1 26 ? 101.253 80.678  118.618 1.00 65.12  ? 26 SER A  CB  1 
ATOM   1652 O OG  . SER G 1 26 ? 99.850  80.707  118.808 1.00 62.29  ? 26 SER A  OG  1 
ATOM   1653 N N   . ASN G 1 27 ? 103.889 83.257  119.146 1.00 58.74  ? 27 ASN A  N   1 
ATOM   1654 C CA  . ASN G 1 27 ? 105.229 83.608  118.695 1.00 53.96  ? 27 ASN A  CA  1 
ATOM   1655 C C   . ASN G 1 27 ? 106.253 82.704  119.366 1.00 54.07  ? 27 ASN A  C   1 
ATOM   1656 O O   . ASN G 1 27 ? 106.346 82.666  120.596 1.00 61.28  ? 27 ASN A  O   1 
ATOM   1657 C CB  . ASN G 1 27 ? 105.525 85.073  119.002 1.00 53.66  ? 27 ASN A  CB  1 
ATOM   1658 C CG  . ASN G 1 27 ? 107.009 85.369  119.044 1.00 48.69  ? 27 ASN A  CG  1 
ATOM   1659 O OD1 . ASN G 1 27 ? 107.725 85.151  118.070 1.00 46.96  ? 27 ASN A  OD1 1 
ATOM   1660 N ND2 . ASN G 1 27 ? 107.481 85.869  120.178 1.00 48.76  ? 27 ASN A  ND2 1 
ATOM   1661 N N   . LYS G 1 28 ? 107.018 81.973  118.560 1.00 49.39  ? 28 LYS A  N   1 
ATOM   1662 C CA  . LYS G 1 28 ? 108.090 81.126  119.061 1.00 50.70  ? 28 LYS A  CA  1 
ATOM   1663 C C   . LYS G 1 28 ? 109.471 81.680  118.752 1.00 50.43  ? 28 LYS A  C   1 
ATOM   1664 O O   . LYS G 1 28 ? 110.471 81.052  119.113 1.00 47.12  ? 28 LYS A  O   1 
ATOM   1665 C CB  . LYS G 1 28 ? 107.960 79.712  118.486 1.00 51.94  ? 28 LYS A  CB  1 
ATOM   1666 C CG  . LYS G 1 28 ? 106.592 79.091  118.691 1.00 54.88  ? 28 LYS A  CG  1 
ATOM   1667 C CD  . LYS G 1 28 ? 106.671 77.576  118.704 1.00 56.29  ? 28 LYS A  CD  1 
ATOM   1668 C CE  . LYS G 1 28 ? 105.287 76.954  118.758 1.00 61.55  ? 28 LYS A  CE  1 
ATOM   1669 N NZ  . LYS G 1 28 ? 104.214 77.985  118.755 1.00 55.99  ? 28 LYS A  NZ  1 
ATOM   1670 N N   . GLY G 1 29 ? 109.555 82.836  118.094 1.00 54.52  ? 29 GLY A  N   1 
ATOM   1671 C CA  . GLY G 1 29 ? 110.807 83.463  117.772 1.00 50.66  ? 29 GLY A  CA  1 
ATOM   1672 C C   . GLY G 1 29 ? 111.055 84.717  118.583 1.00 49.00  ? 29 GLY A  C   1 
ATOM   1673 O O   . GLY G 1 29 ? 110.424 84.961  119.620 1.00 48.69  ? 29 GLY A  O   1 
ATOM   1674 N N   . ALA G 1 30 ? 111.986 85.531  118.099 1.00 48.30  ? 30 ALA A  N   1 
ATOM   1675 C CA  . ALA G 1 30 ? 112.381 86.764  118.765 1.00 41.05  ? 30 ALA A  CA  1 
ATOM   1676 C C   . ALA G 1 30 ? 111.777 87.949  118.026 1.00 40.65  ? 30 ALA A  C   1 
ATOM   1677 O O   . ALA G 1 30 ? 111.978 88.098  116.817 1.00 43.98  ? 30 ALA A  O   1 
ATOM   1678 C CB  . ALA G 1 30 ? 113.902 86.889  118.825 1.00 35.72  ? 30 ALA A  CB  1 
ATOM   1679 N N   . ILE G 1 31 ? 111.043 88.786  118.750 1.00 38.51  ? 31 ILE A  N   1 
ATOM   1680 C CA  . ILE G 1 31 ? 110.500 90.031  118.224 1.00 37.05  ? 31 ILE A  CA  1 
ATOM   1681 C C   . ILE G 1 31 ? 111.174 91.165  118.980 1.00 40.18  ? 31 ILE A  C   1 
ATOM   1682 O O   . ILE G 1 31 ? 110.867 91.408  120.153 1.00 49.66  ? 31 ILE A  O   1 
ATOM   1683 C CB  . ILE G 1 31 ? 108.976 90.095  118.363 1.00 33.50  ? 31 ILE A  CB  1 
ATOM   1684 C CG1 . ILE G 1 31 ? 108.334 88.946  117.591 1.00 38.10  ? 31 ILE A  CG1 1 
ATOM   1685 C CG2 . ILE G 1 31 ? 108.454 91.435  117.875 1.00 30.82  ? 31 ILE A  CG2 1 
ATOM   1686 C CD1 . ILE G 1 31 ? 106.862 89.113  117.374 1.00 42.08  ? 31 ILE A  CD1 1 
ATOM   1687 N N   . ILE G 1 32 ? 112.090 91.861  118.316 1.00 37.80  ? 32 ILE A  N   1 
ATOM   1688 C CA  . ILE G 1 32 ? 112.933 92.862  118.953 1.00 42.84  ? 32 ILE A  CA  1 
ATOM   1689 C C   . ILE G 1 32 ? 112.740 94.195  118.248 1.00 42.30  ? 32 ILE A  C   1 
ATOM   1690 O O   . ILE G 1 32 ? 112.670 94.252  117.017 1.00 45.16  ? 32 ILE A  O   1 
ATOM   1691 C CB  . ILE G 1 32 ? 114.417 92.445  118.937 1.00 44.85  ? 32 ILE A  CB  1 
ATOM   1692 C CG1 . ILE G 1 32 ? 114.572 91.009  119.437 1.00 42.64  ? 32 ILE A  CG1 1 
ATOM   1693 C CG2 . ILE G 1 32 ? 115.240 93.382  119.794 1.00 48.55  ? 32 ILE A  CG2 1 
ATOM   1694 C CD1 . ILE G 1 32 ? 115.589 90.203  118.671 1.00 40.67  ? 32 ILE A  CD1 1 
ATOM   1695 N N   . GLY G 1 33 ? 112.640 95.264  119.030 1.00 44.70  ? 33 GLY A  N   1 
ATOM   1696 C CA  . GLY G 1 33 ? 112.563 96.595  118.467 1.00 40.70  ? 33 GLY A  CA  1 
ATOM   1697 C C   . GLY G 1 33 ? 113.905 97.065  117.949 1.00 40.23  ? 33 GLY A  C   1 
ATOM   1698 O O   . GLY G 1 33 ? 114.054 97.348  116.759 1.00 43.73  ? 33 GLY A  O   1 
ATOM   1699 N N   . LEU G 1 34 ? 114.890 97.156  118.836 1.00 41.37  ? 34 LEU A  N   1 
ATOM   1700 C CA  . LEU G 1 34 ? 116.258 97.492  118.465 1.00 41.56  ? 34 LEU A  CA  1 
ATOM   1701 C C   . LEU G 1 34 ? 117.174 96.424  119.037 1.00 43.59  ? 34 LEU A  C   1 
ATOM   1702 O O   . LEU G 1 34 ? 117.172 96.191  120.249 1.00 52.62  ? 34 LEU A  O   1 
ATOM   1703 C CB  . LEU G 1 34 ? 116.655 98.874  118.986 1.00 42.98  ? 34 LEU A  CB  1 
ATOM   1704 C CG  . LEU G 1 34 ? 117.906 99.503  118.372 1.00 39.98  ? 34 LEU A  CG  1 
ATOM   1705 C CD1 . LEU G 1 34 ? 117.630 100.944 117.990 1.00 33.09  ? 34 LEU A  CD1 1 
ATOM   1706 C CD2 . LEU G 1 34 ? 119.091 99.412  119.312 1.00 40.03  ? 34 LEU A  CD2 1 
ATOM   1707 N N   . MET G 1 35 ? 117.951 95.779  118.176 1.00 38.84  ? 35 MET A  N   1 
ATOM   1708 C CA  . MET G 1 35 ? 118.849 94.710  118.585 1.00 44.10  ? 35 MET A  CA  1 
ATOM   1709 C C   . MET G 1 35 ? 120.262 95.041  118.134 1.00 48.26  ? 35 MET A  C   1 
ATOM   1710 O O   . MET G 1 35 ? 120.485 95.355  116.962 1.00 57.64  ? 35 MET A  O   1 
ATOM   1711 C CB  . MET G 1 35 ? 118.408 93.370  117.998 1.00 46.59  ? 35 MET A  CB  1 
ATOM   1712 C CG  . MET G 1 35 ? 119.495 92.320  117.991 1.00 51.67  ? 35 MET A  CG  1 
ATOM   1713 S SD  . MET G 1 35 ? 119.446 91.241  119.424 1.00 73.51  ? 35 MET A  SD  1 
ATOM   1714 C CE  . MET G 1 35 ? 121.061 90.481  119.329 1.00 71.03  ? 35 MET A  CE  1 
ATOM   1715 N N   . VAL G 1 36 ? 121.209 94.975  119.063 1.00 48.97  ? 36 VAL A  N   1 
ATOM   1716 C CA  . VAL G 1 36 ? 122.624 95.164  118.770 1.00 50.21  ? 36 VAL A  CA  1 
ATOM   1717 C C   . VAL G 1 36 ? 123.361 93.924  119.248 1.00 56.88  ? 36 VAL A  C   1 
ATOM   1718 O O   . VAL G 1 36 ? 123.223 93.524  120.410 1.00 64.00  ? 36 VAL A  O   1 
ATOM   1719 C CB  . VAL G 1 36 ? 123.187 96.428  119.436 1.00 46.62  ? 36 VAL A  CB  1 
ATOM   1720 C CG1 . VAL G 1 36 ? 124.674 96.547  119.164 1.00 48.09  ? 36 VAL A  CG1 1 
ATOM   1721 C CG2 . VAL G 1 36 ? 122.450 97.659  118.942 1.00 41.47  ? 36 VAL A  CG2 1 
ATOM   1722 N N   . GLY G 1 37 ? 124.141 93.318  118.360 1.00 56.15  ? 37 GLY A  N   1 
ATOM   1723 C CA  . GLY G 1 37 ? 124.843 92.098  118.699 1.00 61.50  ? 37 GLY A  CA  1 
ATOM   1724 C C   . GLY G 1 37 ? 124.735 91.037  117.627 1.00 74.49  ? 37 GLY A  C   1 
ATOM   1725 O O   . GLY G 1 37 ? 125.197 91.238  116.501 1.00 81.43  ? 37 GLY A  O   1 
ATOM   1726 N N   . GLY G 1 38 ? 124.140 89.903  117.961 1.00 77.39  ? 38 GLY A  N   1 
ATOM   1727 C CA  . GLY G 1 38 ? 123.996 88.821  117.003 1.00 82.98  ? 38 GLY A  CA  1 
ATOM   1728 C C   . GLY G 1 38 ? 122.770 87.992  117.302 1.00 87.96  ? 38 GLY A  C   1 
ATOM   1729 O O   . GLY G 1 38 ? 122.463 87.699  118.461 1.00 86.27  ? 38 GLY A  O   1 
ATOM   1730 N N   . VAL G 1 39 ? 122.068 87.605  116.241 1.00 90.26  ? 39 VAL A  N   1 
ATOM   1731 C CA  . VAL G 1 39 ? 120.870 86.782  116.338 1.00 94.48  ? 39 VAL A  CA  1 
ATOM   1732 C C   . VAL G 1 39 ? 121.127 85.478  115.598 1.00 97.76  ? 39 VAL A  C   1 
ATOM   1733 O O   . VAL G 1 39 ? 121.455 85.489  114.406 1.00 93.80  ? 39 VAL A  O   1 
ATOM   1734 C CB  . VAL G 1 39 ? 119.637 87.503  115.765 1.00 91.47  ? 39 VAL A  CB  1 
ATOM   1735 C CG1 . VAL G 1 39 ? 118.512 86.515  115.516 1.00 90.96  ? 39 VAL A  CG1 1 
ATOM   1736 C CG2 . VAL G 1 39 ? 119.183 88.599  116.709 1.00 86.64  ? 39 VAL A  CG2 1 
ATOM   1737 N N   . VAL G 1 40 ? 120.981 84.361  116.304 1.00 101.84 ? 40 VAL A  N   1 
ATOM   1738 C CA  . VAL G 1 40 ? 121.135 83.031  115.731 1.00 102.74 ? 40 VAL A  CA  1 
ATOM   1739 C C   . VAL G 1 40 ? 119.814 82.298  115.904 1.00 105.52 ? 40 VAL A  C   1 
ATOM   1740 O O   . VAL G 1 40 ? 119.315 82.165  117.028 1.00 105.13 ? 40 VAL A  O   1 
ATOM   1741 C CB  . VAL G 1 40 ? 122.285 82.252  116.387 1.00 100.19 ? 40 VAL A  CB  1 
ATOM   1742 C CG1 . VAL G 1 40 ? 122.452 80.898  115.721 1.00 98.42  ? 40 VAL A  CG1 1 
ATOM   1743 C CG2 . VAL G 1 40 ? 123.576 83.050  116.309 1.00 97.85  ? 40 VAL A  CG2 1 
ATOM   1744 N N   . ILE G 1 41 ? 119.252 81.822  114.798 1.00 108.51 ? 41 ILE A  N   1 
ATOM   1745 C CA  . ILE G 1 41 ? 117.973 81.124  114.800 1.00 112.67 ? 41 ILE A  CA  1 
ATOM   1746 C C   . ILE G 1 41 ? 118.216 79.664  114.452 1.00 116.23 ? 41 ILE A  C   1 
ATOM   1747 O O   . ILE G 1 41 ? 118.849 79.356  113.434 1.00 115.97 ? 41 ILE A  O   1 
ATOM   1748 C CB  . ILE G 1 41 ? 116.986 81.767  113.812 1.00 112.79 ? 41 ILE A  CB  1 
ATOM   1749 C CG1 . ILE G 1 41 ? 116.907 83.275  114.048 1.00 107.76 ? 41 ILE A  CG1 1 
ATOM   1750 C CG2 . ILE G 1 41 ? 115.611 81.136  113.948 1.00 110.95 ? 41 ILE A  CG2 1 
ATOM   1751 C CD1 . ILE G 1 41 ? 116.086 84.005  113.014 1.00 104.16 ? 41 ILE A  CD1 1 
ATOM   1752 N N   . ALA G 1 42 ? 117.718 78.766  115.295 1.00 118.92 ? 42 ALA A  N   1 
ATOM   1753 C CA  . ALA G 1 42 ? 117.886 77.336  115.076 1.00 121.66 ? 42 ALA A  CA  1 
ATOM   1754 C C   . ALA G 1 42 ? 116.653 76.568  115.540 1.00 127.02 ? 42 ALA A  C   1 
ATOM   1755 O O   . ALA G 1 42 ? 115.803 77.104  116.251 1.00 129.60 ? 42 ALA A  O   1 
ATOM   1756 C CB  . ALA G 1 42 ? 119.127 76.833  115.793 1.00 117.58 ? 42 ALA A  CB  1 
ATOM   1757 O OXT . ALA G 1 42 ? 116.476 75.395  115.214 1.00 127.70 ? 42 ALA A  OXT 1 
ATOM   1758 N N   . GLY H 1 9  ? 134.673 98.219  112.439 1.00 75.58  ? 9  GLY B  N   1 
ATOM   1759 C CA  . GLY H 1 9  ? 133.850 98.941  113.391 1.00 77.59  ? 9  GLY B  CA  1 
ATOM   1760 C C   . GLY H 1 9  ? 132.647 99.607  112.754 1.00 77.76  ? 9  GLY B  C   1 
ATOM   1761 O O   . GLY H 1 9  ? 132.760 100.234 111.703 1.00 78.65  ? 9  GLY B  O   1 
ATOM   1762 N N   . TYR H 1 10 ? 131.491 99.473  113.395 1.00 74.83  ? 10 TYR B  N   1 
ATOM   1763 C CA  . TYR H 1 10 ? 130.243 100.039 112.903 1.00 70.87  ? 10 TYR B  CA  1 
ATOM   1764 C C   . TYR H 1 10 ? 129.885 101.262 113.734 1.00 65.85  ? 10 TYR B  C   1 
ATOM   1765 O O   . TYR H 1 10 ? 129.944 101.218 114.966 1.00 68.66  ? 10 TYR B  O   1 
ATOM   1766 C CB  . TYR H 1 10 ? 129.106 99.017  112.963 1.00 71.13  ? 10 TYR B  CB  1 
ATOM   1767 C CG  . TYR H 1 10 ? 129.337 97.762  112.151 1.00 81.03  ? 10 TYR B  CG  1 
ATOM   1768 C CD1 . TYR H 1 10 ? 130.300 97.717  111.153 1.00 83.11  ? 10 TYR B  CD1 1 
ATOM   1769 C CD2 . TYR H 1 10 ? 128.580 96.622  112.378 1.00 80.21  ? 10 TYR B  CD2 1 
ATOM   1770 C CE1 . TYR H 1 10 ? 130.510 96.570  110.414 1.00 84.09  ? 10 TYR B  CE1 1 
ATOM   1771 C CE2 . TYR H 1 10 ? 128.781 95.472  111.643 1.00 87.12  ? 10 TYR B  CE2 1 
ATOM   1772 C CZ  . TYR H 1 10 ? 129.746 95.452  110.661 1.00 91.17  ? 10 TYR B  CZ  1 
ATOM   1773 O OH  . TYR H 1 10 ? 129.950 94.308  109.925 1.00 91.09  ? 10 TYR B  OH  1 
ATOM   1774 N N   . GLU H 1 11 ? 129.518 102.347 113.061 1.00 61.80  ? 11 GLU B  N   1 
ATOM   1775 C CA  . GLU H 1 11 ? 129.080 103.576 113.716 1.00 57.88  ? 11 GLU B  CA  1 
ATOM   1776 C C   . GLU H 1 11 ? 127.710 103.938 113.154 1.00 52.72  ? 11 GLU B  C   1 
ATOM   1777 O O   . GLU H 1 11 ? 127.611 104.541 112.082 1.00 58.89  ? 11 GLU B  O   1 
ATOM   1778 C CB  . GLU H 1 11 ? 130.083 104.703 113.508 1.00 61.88  ? 11 GLU B  CB  1 
ATOM   1779 C CG  . GLU H 1 11 ? 129.994 105.799 114.552 1.00 65.71  ? 11 GLU B  CG  1 
ATOM   1780 C CD  . GLU H 1 11 ? 130.820 107.015 114.190 1.00 76.41  ? 11 GLU B  CD  1 
ATOM   1781 O OE1 . GLU H 1 11 ? 132.028 106.855 113.917 1.00 81.59  ? 11 GLU B  OE1 1 
ATOM   1782 O OE2 . GLU H 1 11 ? 130.263 108.132 114.184 1.00 75.54  ? 11 GLU B  OE2 1 
ATOM   1783 N N   . VAL H 1 12 ? 126.660 103.570 113.879 1.00 47.56  ? 12 VAL B  N   1 
ATOM   1784 C CA  . VAL H 1 12 ? 125.282 103.807 113.468 1.00 41.82  ? 12 VAL B  CA  1 
ATOM   1785 C C   . VAL H 1 12 ? 124.692 104.846 114.408 1.00 43.59  ? 12 VAL B  C   1 
ATOM   1786 O O   . VAL H 1 12 ? 124.718 104.666 115.630 1.00 54.65  ? 12 VAL B  O   1 
ATOM   1787 C CB  . VAL H 1 12 ? 124.462 102.510 113.492 1.00 38.02  ? 12 VAL B  CB  1 
ATOM   1788 C CG1 . VAL H 1 12 ? 123.082 102.739 112.919 1.00 36.81  ? 12 VAL B  CG1 1 
ATOM   1789 C CG2 . VAL H 1 12 ? 125.185 101.416 112.732 1.00 37.82  ? 12 VAL B  CG2 1 
ATOM   1790 N N   . HIS H 1 13 ? 124.162 105.933 113.852 1.00 39.40  ? 13 HIS B  N   1 
ATOM   1791 C CA  . HIS H 1 13 ? 123.557 106.953 114.694 1.00 42.52  ? 13 HIS B  CA  1 
ATOM   1792 C C   . HIS H 1 13 ? 122.487 107.712 113.926 1.00 39.69  ? 13 HIS B  C   1 
ATOM   1793 O O   . HIS H 1 13 ? 122.398 107.632 112.703 1.00 38.87  ? 13 HIS B  O   1 
ATOM   1794 C CB  . HIS H 1 13 ? 124.597 107.928 115.263 1.00 45.91  ? 13 HIS B  CB  1 
ATOM   1795 C CG  . HIS H 1 13 ? 125.625 108.384 114.275 1.00 46.41  ? 13 HIS B  CG  1 
ATOM   1796 N ND1 . HIS H 1 13 ? 125.751 109.701 113.893 1.00 43.92  ? 13 HIS B  ND1 1 
ATOM   1797 C CD2 . HIS H 1 13 ? 126.599 107.708 113.622 1.00 49.27  ? 13 HIS B  CD2 1 
ATOM   1798 C CE1 . HIS H 1 13 ? 126.745 109.813 113.031 1.00 48.42  ? 13 HIS B  CE1 1 
ATOM   1799 N NE2 . HIS H 1 13 ? 127.275 108.618 112.849 1.00 50.84  ? 13 HIS B  NE2 1 
ATOM   1800 N N   . HIS H 1 14 ? 121.653 108.428 114.679 1.00 39.43  ? 14 HIS B  N   1 
ATOM   1801 C CA  . HIS H 1 14 ? 120.627 109.318 114.136 1.00 36.41  ? 14 HIS B  CA  1 
ATOM   1802 C C   . HIS H 1 14 ? 119.664 108.573 113.211 1.00 34.91  ? 14 HIS B  C   1 
ATOM   1803 O O   . HIS H 1 14 ? 119.571 108.843 112.017 1.00 41.49  ? 14 HIS B  O   1 
ATOM   1804 C CB  . HIS H 1 14 ? 121.266 110.513 113.429 1.00 37.87  ? 14 HIS B  CB  1 
ATOM   1805 C CG  . HIS H 1 14 ? 121.987 111.438 114.356 1.00 43.65  ? 14 HIS B  CG  1 
ATOM   1806 N ND1 . HIS H 1 14 ? 123.325 111.298 114.654 1.00 45.90  ? 14 HIS B  ND1 1 
ATOM   1807 C CD2 . HIS H 1 14 ? 121.551 112.501 115.071 1.00 47.98  ? 14 HIS B  CD2 1 
ATOM   1808 C CE1 . HIS H 1 14 ? 123.685 112.243 115.503 1.00 53.85  ? 14 HIS B  CE1 1 
ATOM   1809 N NE2 . HIS H 1 14 ? 122.627 112.986 115.772 1.00 57.15  ? 14 HIS B  NE2 1 
ATOM   1810 N N   . GLN H 1 15 ? 118.932 107.629 113.792 1.00 31.09  ? 15 GLN B  N   1 
ATOM   1811 C CA  . GLN H 1 15 ? 117.928 106.862 113.070 1.00 25.82  ? 15 GLN B  CA  1 
ATOM   1812 C C   . GLN H 1 15 ? 116.558 107.132 113.667 1.00 27.11  ? 15 GLN B  C   1 
ATOM   1813 O O   . GLN H 1 15 ? 116.387 107.073 114.888 1.00 36.68  ? 15 GLN B  O   1 
ATOM   1814 C CB  . GLN H 1 15 ? 118.234 105.367 113.121 1.00 26.86  ? 15 GLN B  CB  1 
ATOM   1815 C CG  . GLN H 1 15 ? 118.967 104.856 111.907 1.00 36.02  ? 15 GLN B  CG  1 
ATOM   1816 C CD  . GLN H 1 15 ? 120.460 104.927 112.074 1.00 36.75  ? 15 GLN B  CD  1 
ATOM   1817 O OE1 . GLN H 1 15 ? 120.960 105.118 113.179 1.00 32.60  ? 15 GLN B  OE1 1 
ATOM   1818 N NE2 . GLN H 1 15 ? 121.187 104.781 110.975 1.00 36.88  ? 15 GLN B  NE2 1 
ATOM   1819 N N   . LYS H 1 16 ? 115.590 107.431 112.810 1.00 25.46  ? 16 LYS B  N   1 
ATOM   1820 C CA  . LYS H 1 16 ? 114.192 107.575 113.208 1.00 23.75  ? 16 LYS B  CA  1 
ATOM   1821 C C   . LYS H 1 16 ? 113.418 106.457 112.524 1.00 27.50  ? 16 LYS B  C   1 
ATOM   1822 O O   . LYS H 1 16 ? 113.102 106.550 111.335 1.00 37.91  ? 16 LYS B  O   1 
ATOM   1823 C CB  . LYS H 1 16 ? 113.645 108.944 112.833 1.00 23.54  ? 16 LYS B  CB  1 
ATOM   1824 C CG  . LYS H 1 16 ? 114.430 110.093 113.410 1.00 20.89  ? 16 LYS B  CG  1 
ATOM   1825 C CD  . LYS H 1 16 ? 113.732 111.403 113.145 1.00 22.06  ? 16 LYS B  CD  1 
ATOM   1826 C CE  . LYS H 1 16 ? 114.481 112.552 113.775 1.00 22.83  ? 16 LYS B  CE  1 
ATOM   1827 N NZ  . LYS H 1 16 ? 113.644 113.773 113.801 1.00 28.31  ? 16 LYS B  NZ  1 
ATOM   1828 N N   . LEU H 1 17 ? 113.114 105.403 113.271 1.00 23.96  ? 17 LEU B  N   1 
ATOM   1829 C CA  . LEU H 1 17 ? 112.500 104.204 112.723 1.00 25.08  ? 17 LEU B  CA  1 
ATOM   1830 C C   . LEU H 1 17 ? 111.105 104.031 113.300 1.00 25.06  ? 17 LEU B  C   1 
ATOM   1831 O O   . LEU H 1 17 ? 110.919 104.114 114.517 1.00 32.20  ? 17 LEU B  O   1 
ATOM   1832 C CB  . LEU H 1 17 ? 113.354 102.973 113.028 1.00 25.85  ? 17 LEU B  CB  1 
ATOM   1833 C CG  . LEU H 1 17 ? 113.057 101.712 112.220 1.00 28.96  ? 17 LEU B  CG  1 
ATOM   1834 C CD1 . LEU H 1 17 ? 114.354 101.070 111.780 1.00 37.70  ? 17 LEU B  CD1 1 
ATOM   1835 C CD2 . LEU H 1 17 ? 112.226 100.735 113.029 1.00 27.85  ? 17 LEU B  CD2 1 
ATOM   1836 N N   . VAL H 1 18 ? 110.130 103.799 112.428 1.00 24.89  ? 18 VAL B  N   1 
ATOM   1837 C CA  . VAL H 1 18 ? 108.776 103.442 112.826 1.00 26.58  ? 18 VAL B  CA  1 
ATOM   1838 C C   . VAL H 1 18 ? 108.445 102.099 112.197 1.00 29.85  ? 18 VAL B  C   1 
ATOM   1839 O O   . VAL H 1 18 ? 108.581 101.928 110.982 1.00 35.03  ? 18 VAL B  O   1 
ATOM   1840 C CB  . VAL H 1 18 ? 107.749 104.510 112.411 1.00 25.75  ? 18 VAL B  CB  1 
ATOM   1841 C CG1 . VAL H 1 18 ? 106.437 104.266 113.117 1.00 24.22  ? 18 VAL B  CG1 1 
ATOM   1842 C CG2 . VAL H 1 18 ? 108.269 105.894 112.734 1.00 24.63  ? 18 VAL B  CG2 1 
ATOM   1843 N N   . PHE H 1 19 ? 108.016 101.151 113.023 1.00 30.43  ? 19 PHE B  N   1 
ATOM   1844 C CA  . PHE H 1 19 ? 107.775 99.780  112.596 1.00 32.79  ? 19 PHE B  CA  1 
ATOM   1845 C C   . PHE H 1 19 ? 106.337 99.407  112.916 1.00 36.31  ? 19 PHE B  C   1 
ATOM   1846 O O   . PHE H 1 19 ? 105.948 99.376  114.087 1.00 43.04  ? 19 PHE B  O   1 
ATOM   1847 C CB  . PHE H 1 19 ? 108.749 98.825  113.288 1.00 36.08  ? 19 PHE B  CB  1 
ATOM   1848 C CG  . PHE H 1 19 ? 108.866 97.485  112.628 1.00 38.70  ? 19 PHE B  CG  1 
ATOM   1849 C CD1 . PHE H 1 19 ? 107.867 96.540  112.765 1.00 38.82  ? 19 PHE B  CD1 1 
ATOM   1850 C CD2 . PHE H 1 19 ? 109.983 97.165  111.883 1.00 41.78  ? 19 PHE B  CD2 1 
ATOM   1851 C CE1 . PHE H 1 19 ? 107.975 95.307  112.164 1.00 39.93  ? 19 PHE B  CE1 1 
ATOM   1852 C CE2 . PHE H 1 19 ? 110.096 95.932  111.280 1.00 44.10  ? 19 PHE B  CE2 1 
ATOM   1853 C CZ  . PHE H 1 19 ? 109.091 95.003  111.421 1.00 44.51  ? 19 PHE B  CZ  1 
ATOM   1854 N N   . PHE H 1 20 ? 105.555 99.121  111.881 1.00 35.86  ? 20 PHE B  N   1 
ATOM   1855 C CA  . PHE H 1 20 ? 104.192 98.634  112.029 1.00 37.59  ? 20 PHE B  CA  1 
ATOM   1856 C C   . PHE H 1 20 ? 104.157 97.157  111.674 1.00 45.25  ? 20 PHE B  C   1 
ATOM   1857 O O   . PHE H 1 20 ? 104.690 96.753  110.637 1.00 55.23  ? 20 PHE B  O   1 
ATOM   1858 C CB  . PHE H 1 20 ? 103.222 99.401  111.131 1.00 39.09  ? 20 PHE B  CB  1 
ATOM   1859 C CG  . PHE H 1 20 ? 103.033 100.835 111.516 1.00 38.58  ? 20 PHE B  CG  1 
ATOM   1860 C CD1 . PHE H 1 20 ? 103.848 101.818 110.990 1.00 36.65  ? 20 PHE B  CD1 1 
ATOM   1861 C CD2 . PHE H 1 20 ? 102.026 101.205 112.385 1.00 35.18  ? 20 PHE B  CD2 1 
ATOM   1862 C CE1 . PHE H 1 20 ? 103.668 103.137 111.332 1.00 33.87  ? 20 PHE B  CE1 1 
ATOM   1863 C CE2 . PHE H 1 20 ? 101.843 102.525 112.730 1.00 34.77  ? 20 PHE B  CE2 1 
ATOM   1864 C CZ  . PHE H 1 20 ? 102.666 103.491 112.204 1.00 31.87  ? 20 PHE B  CZ  1 
ATOM   1865 N N   . ALA H 1 21 ? 103.536 96.356  112.531 1.00 46.71  ? 21 ALA B  N   1 
ATOM   1866 C CA  . ALA H 1 21 ? 103.363 94.935  112.279 1.00 51.62  ? 21 ALA B  CA  1 
ATOM   1867 C C   . ALA H 1 21 ? 101.922 94.549  112.562 1.00 59.08  ? 21 ALA B  C   1 
ATOM   1868 O O   . ALA H 1 21 ? 101.335 94.995  113.551 1.00 64.50  ? 21 ALA B  O   1 
ATOM   1869 C CB  . ALA H 1 21 ? 104.314 94.094  113.133 1.00 47.68  ? 21 ALA B  CB  1 
ATOM   1870 N N   . GLU H 1 22 ? 101.353 93.728  111.689 1.00 62.23  ? 22 GLU B  N   1 
ATOM   1871 C CA  . GLU H 1 22 ? 99.988  93.259  111.869 1.00 69.45  ? 22 GLU B  CA  1 
ATOM   1872 C C   . GLU H 1 22 ? 99.902  91.756  111.665 1.00 74.34  ? 22 GLU B  C   1 
ATOM   1873 O O   . GLU H 1 22 ? 100.656 91.184  110.881 1.00 78.12  ? 22 GLU B  O   1 
ATOM   1874 C CB  . GLU H 1 22 ? 99.040  93.973  110.910 1.00 72.05  ? 22 GLU B  CB  1 
ATOM   1875 C CG  . GLU H 1 22 ? 98.605  95.340  111.387 1.00 71.84  ? 22 GLU B  CG  1 
ATOM   1876 C CD  . GLU H 1 22 ? 97.153  95.368  111.815 1.00 75.14  ? 22 GLU B  CD  1 
ATOM   1877 O OE1 . GLU H 1 22 ? 96.547  94.283  111.932 1.00 75.71  ? 22 GLU B  OE1 1 
ATOM   1878 O OE2 . GLU H 1 22 ? 96.617  96.475  112.035 1.00 74.25  ? 22 GLU B  OE2 1 
HETATM 1879 N N   . DAS H 1 23 ? 98.976  91.122  112.372 1.00 72.71  ? 23 DAS B  N   1 
HETATM 1880 C CA  . DAS H 1 23 ? 98.823  89.679  112.302 1.00 76.75  ? 23 DAS B  CA  1 
HETATM 1881 C C   . DAS H 1 23 ? 100.009 89.012  112.986 1.00 76.02  ? 23 DAS B  C   1 
HETATM 1882 O O   . DAS H 1 23 ? 100.005 88.825  114.201 1.00 76.84  ? 23 DAS B  O   1 
HETATM 1883 C CB  . DAS H 1 23 ? 97.517  89.251  112.969 1.00 83.90  ? 23 DAS B  CB  1 
HETATM 1884 C CG  . DAS H 1 23 ? 97.177  87.796  112.711 1.00 88.14  ? 23 DAS B  CG  1 
HETATM 1885 O OD1 . DAS H 1 23 ? 97.872  87.155  111.896 1.00 87.21  ? 23 DAS B  OD1 1 
HETATM 1886 O OD2 . DAS H 1 23 ? 96.212  87.293  113.325 1.00 86.54  ? 23 DAS B  OD2 1 
ATOM   1887 N N   . VAL H 1 24 ? 101.021 88.671  112.192 1.00 73.27  ? 24 VAL B  N   1 
ATOM   1888 C CA  . VAL H 1 24 ? 102.236 88.023  112.681 1.00 69.90  ? 24 VAL B  CA  1 
ATOM   1889 C C   . VAL H 1 24 ? 101.905 86.799  113.528 1.00 67.77  ? 24 VAL B  C   1 
ATOM   1890 O O   . VAL H 1 24 ? 102.102 86.798  114.740 1.00 70.39  ? 24 VAL B  O   1 
ATOM   1891 C CB  . VAL H 1 24 ? 103.114 89.010  113.470 1.00 64.79  ? 24 VAL B  CB  1 
ATOM   1892 C CG1 . VAL H 1 24 ? 104.500 88.433  113.674 1.00 56.42  ? 24 VAL B  CG1 1 
ATOM   1893 C CG2 . VAL H 1 24 ? 103.200 90.339  112.745 1.00 58.59  ? 24 VAL B  CG2 1 
ATOM   1894 N N   . GLY H 1 25 ? 101.394 85.753  112.884 1.00 65.16  ? 25 GLY B  N   1 
ATOM   1895 C CA  . GLY H 1 25 ? 100.992 84.544  113.577 1.00 63.72  ? 25 GLY B  CA  1 
ATOM   1896 C C   . GLY H 1 25 ? 102.041 83.456  113.439 1.00 65.69  ? 25 GLY B  C   1 
ATOM   1897 O O   . GLY H 1 25 ? 102.572 83.224  112.351 1.00 67.63  ? 25 GLY B  O   1 
ATOM   1898 N N   . SER H 1 26 ? 102.329 82.795  114.560 1.00 66.41  ? 26 SER B  N   1 
ATOM   1899 C CA  . SER H 1 26 ? 103.239 81.651  114.601 1.00 66.74  ? 26 SER B  CA  1 
ATOM   1900 C C   . SER H 1 26 ? 104.607 82.002  114.018 1.00 62.57  ? 26 SER B  C   1 
ATOM   1901 O O   . SER H 1 26 ? 105.187 81.251  113.232 1.00 59.58  ? 26 SER B  O   1 
ATOM   1902 C CB  . SER H 1 26 ? 102.631 80.445  113.882 1.00 65.12  ? 26 SER B  CB  1 
ATOM   1903 O OG  . SER H 1 26 ? 101.227 80.399  114.068 1.00 62.29  ? 26 SER B  OG  1 
ATOM   1904 N N   . ASN H 1 27 ? 105.124 83.161  114.413 1.00 58.74  ? 27 ASN B  N   1 
ATOM   1905 C CA  . ASN H 1 27 ? 106.444 83.584  113.964 1.00 53.96  ? 27 ASN B  CA  1 
ATOM   1906 C C   . ASN H 1 27 ? 107.514 82.736  114.638 1.00 54.07  ? 27 ASN B  C   1 
ATOM   1907 O O   . ASN H 1 27 ? 107.606 82.703  115.869 1.00 61.28  ? 27 ASN B  O   1 
ATOM   1908 C CB  . ASN H 1 27 ? 106.660 85.062  114.272 1.00 53.66  ? 27 ASN B  CB  1 
ATOM   1909 C CG  . ASN H 1 27 ? 108.127 85.438  114.317 1.00 48.69  ? 27 ASN B  CG  1 
ATOM   1910 O OD1 . ASN H 1 27 ? 108.855 85.257  113.344 1.00 46.96  ? 27 ASN B  OD1 1 
ATOM   1911 N ND2 . ASN H 1 27 ? 108.569 85.962  115.451 1.00 48.76  ? 27 ASN B  ND2 1 
ATOM   1912 N N   . LYS H 1 28 ? 108.319 82.046  113.834 1.00 49.39  ? 28 LYS B  N   1 
ATOM   1913 C CA  . LYS H 1 28 ? 109.433 81.258  114.337 1.00 50.70  ? 28 LYS B  CA  1 
ATOM   1914 C C   . LYS H 1 28 ? 110.783 81.885  114.031 1.00 50.43  ? 28 LYS B  C   1 
ATOM   1915 O O   . LYS H 1 28 ? 111.814 81.311  114.394 1.00 47.12  ? 28 LYS B  O   1 
ATOM   1916 C CB  . LYS H 1 28 ? 109.380 79.839  113.762 1.00 51.94  ? 28 LYS B  CB  1 
ATOM   1917 C CG  . LYS H 1 28 ? 108.047 79.146  113.965 1.00 54.88  ? 28 LYS B  CG  1 
ATOM   1918 C CD  . LYS H 1 28 ? 108.207 77.638  113.979 1.00 56.29  ? 28 LYS B  CD  1 
ATOM   1919 C CE  . LYS H 1 28 ? 106.858 76.942  114.031 1.00 61.55  ? 28 LYS B  CE  1 
ATOM   1920 N NZ  . LYS H 1 28 ? 105.731 77.914  114.025 1.00 55.99  ? 28 LYS B  NZ  1 
ATOM   1921 N N   . GLY H 1 29 ? 110.806 83.044  113.373 1.00 54.52  ? 29 GLY B  N   1 
ATOM   1922 C CA  . GLY H 1 29 ? 112.024 83.737  113.053 1.00 50.66  ? 29 GLY B  CA  1 
ATOM   1923 C C   . GLY H 1 29 ? 112.203 85.002  113.864 1.00 49.00  ? 29 GLY B  C   1 
ATOM   1924 O O   . GLY H 1 29 ? 111.557 85.212  114.899 1.00 48.69  ? 29 GLY B  O   1 
ATOM   1925 N N   . ALA H 1 30 ? 113.090 85.865  113.382 1.00 48.30  ? 30 ALA B  N   1 
ATOM   1926 C CA  . ALA H 1 30 ? 113.417 87.117  114.048 1.00 41.05  ? 30 ALA B  CA  1 
ATOM   1927 C C   . ALA H 1 30 ? 112.752 88.268  113.307 1.00 40.65  ? 30 ALA B  C   1 
ATOM   1928 O O   . ALA H 1 30 ? 112.947 88.427  112.099 1.00 43.98  ? 30 ALA B  O   1 
ATOM   1929 C CB  . ALA H 1 30 ? 114.929 87.323  114.110 1.00 35.72  ? 30 ALA B  CB  1 
ATOM   1930 N N   . ILE H 1 31 ? 111.973 89.065  114.030 1.00 38.51  ? 31 ILE B  N   1 
ATOM   1931 C CA  . ILE H 1 31 ? 111.366 90.279  113.501 1.00 37.05  ? 31 ILE B  CA  1 
ATOM   1932 C C   . ILE H 1 31 ? 111.976 91.447  114.259 1.00 40.18  ? 31 ILE B  C   1 
ATOM   1933 O O   . ILE H 1 31 ? 111.655 91.674  115.431 1.00 49.66  ? 31 ILE B  O   1 
ATOM   1934 C CB  . ILE H 1 31 ? 109.839 90.262  113.637 1.00 33.50  ? 31 ILE B  CB  1 
ATOM   1935 C CG1 . ILE H 1 31 ? 109.261 89.079  112.865 1.00 38.10  ? 31 ILE B  CG1 1 
ATOM   1936 C CG2 . ILE H 1 31 ? 109.248 91.571  113.148 1.00 30.82  ? 31 ILE B  CG2 1 
ATOM   1937 C CD1 . ILE H 1 31 ? 107.784 89.168  112.645 1.00 42.08  ? 31 ILE B  CD1 1 
ATOM   1938 N N   . ILE H 1 32 ? 112.855 92.191  113.596 1.00 37.80  ? 32 ILE B  N   1 
ATOM   1939 C CA  . ILE H 1 32 ? 113.642 93.236  114.234 1.00 42.84  ? 32 ILE B  CA  1 
ATOM   1940 C C   . ILE H 1 32 ? 113.380 94.556  113.528 1.00 42.30  ? 32 ILE B  C   1 
ATOM   1941 O O   . ILE H 1 32 ? 113.309 94.609  112.297 1.00 45.16  ? 32 ILE B  O   1 
ATOM   1942 C CB  . ILE H 1 32 ? 115.147 92.899  114.221 1.00 44.85  ? 32 ILE B  CB  1 
ATOM   1943 C CG1 . ILE H 1 32 ? 115.377 91.473  114.722 1.00 42.64  ? 32 ILE B  CG1 1 
ATOM   1944 C CG2 . ILE H 1 32 ? 115.916 93.879  115.079 1.00 48.55  ? 32 ILE B  CG2 1 
ATOM   1945 C CD1 . ILE H 1 32 ? 116.437 90.723  113.959 1.00 40.67  ? 32 ILE B  CD1 1 
ATOM   1946 N N   . GLY H 1 33 ? 113.221 95.619  114.310 1.00 44.70  ? 33 GLY B  N   1 
ATOM   1947 C CA  . GLY H 1 33 ? 113.074 96.944  113.746 1.00 40.70  ? 33 GLY B  CA  1 
ATOM   1948 C C   . GLY H 1 33 ? 114.390 97.485  113.230 1.00 40.23  ? 33 GLY B  C   1 
ATOM   1949 O O   . GLY H 1 33 ? 114.526 97.775  112.040 1.00 43.73  ? 33 GLY B  O   1 
ATOM   1950 N N   . LEU H 1 34 ? 115.367 97.629  114.120 1.00 41.37  ? 34 LEU B  N   1 
ATOM   1951 C CA  . LEU H 1 34 ? 116.716 98.037  113.751 1.00 41.56  ? 34 LEU B  CA  1 
ATOM   1952 C C   . LEU H 1 34 ? 117.686 97.020  114.325 1.00 43.59  ? 34 LEU B  C   1 
ATOM   1953 O O   . LEU H 1 34 ? 117.695 96.787  115.537 1.00 52.62  ? 34 LEU B  O   1 
ATOM   1954 C CB  . LEU H 1 34 ? 117.038 99.438  114.273 1.00 42.98  ? 34 LEU B  CB  1 
ATOM   1955 C CG  . LEU H 1 34 ? 118.254 100.133 113.661 1.00 39.98  ? 34 LEU B  CG  1 
ATOM   1956 C CD1 . LEU H 1 34 ? 117.902 101.558 113.277 1.00 33.09  ? 34 LEU B  CD1 1 
ATOM   1957 C CD2 . LEU H 1 34 ? 119.441 100.106 114.603 1.00 40.03  ? 34 LEU B  CD2 1 
ATOM   1958 N N   . MET H 1 35 ? 118.499 96.417  113.466 1.00 38.84  ? 35 MET B  N   1 
ATOM   1959 C CA  . MET H 1 35 ? 119.452 95.398  113.877 1.00 44.10  ? 35 MET B  CA  1 
ATOM   1960 C C   . MET H 1 35 ? 120.846 95.803  113.429 1.00 48.26  ? 35 MET B  C   1 
ATOM   1961 O O   . MET H 1 35 ? 121.054 96.129  112.257 1.00 57.64  ? 35 MET B  O   1 
ATOM   1962 C CB  . MET H 1 35 ? 119.084 94.035  113.290 1.00 46.59  ? 35 MET B  CB  1 
ATOM   1963 C CG  . MET H 1 35 ? 120.226 93.045  113.285 1.00 51.67  ? 35 MET B  CG  1 
ATOM   1964 S SD  . MET H 1 35 ? 120.232 91.965  114.718 1.00 73.51  ? 35 MET B  SD  1 
ATOM   1965 C CE  . MET H 1 35 ? 121.885 91.293  114.627 1.00 71.03  ? 35 MET B  CE  1 
ATOM   1966 N N   . VAL H 1 36 ? 121.794 95.788  114.360 1.00 48.97  ? 36 VAL B  N   1 
ATOM   1967 C CA  . VAL H 1 36 ? 123.197 96.053  114.069 1.00 50.21  ? 36 VAL B  CA  1 
ATOM   1968 C C   . VAL H 1 36 ? 123.998 94.854  114.549 1.00 56.88  ? 36 VAL B  C   1 
ATOM   1969 O O   . VAL H 1 36 ? 123.879 94.448  115.711 1.00 64.00  ? 36 VAL B  O   1 
ATOM   1970 C CB  . VAL H 1 36 ? 123.690 97.345  114.736 1.00 46.62  ? 36 VAL B  CB  1 
ATOM   1971 C CG1 . VAL H 1 36 ? 125.169 97.543  114.467 1.00 48.09  ? 36 VAL B  CG1 1 
ATOM   1972 C CG2 . VAL H 1 36 ? 122.889 98.535  114.239 1.00 41.47  ? 36 VAL B  CG2 1 
ATOM   1973 N N   . GLY H 1 37 ? 124.811 94.290  113.663 1.00 56.15  ? 37 GLY B  N   1 
ATOM   1974 C CA  . GLY H 1 37 ? 125.576 93.110  114.004 1.00 61.50  ? 37 GLY B  CA  1 
ATOM   1975 C C   . GLY H 1 37 ? 125.528 92.044  112.932 1.00 74.49  ? 37 GLY B  C   1 
ATOM   1976 O O   . GLY H 1 37 ? 125.980 92.269  111.807 1.00 81.43  ? 37 GLY B  O   1 
ATOM   1977 N N   . GLY H 1 38 ? 124.994 90.879  113.265 1.00 77.39  ? 38 GLY B  N   1 
ATOM   1978 C CA  . GLY H 1 38 ? 124.909 89.792  112.307 1.00 82.98  ? 38 GLY B  CA  1 
ATOM   1979 C C   . GLY H 1 38 ? 123.729 88.898  112.604 1.00 87.96  ? 38 GLY B  C   1 
ATOM   1980 O O   . GLY H 1 38 ? 123.435 88.590  113.763 1.00 86.27  ? 38 GLY B  O   1 
ATOM   1981 N N   . VAL H 1 39 ? 123.051 88.473  111.542 1.00 90.26  ? 39 VAL B  N   1 
ATOM   1982 C CA  . VAL H 1 39 ? 121.898 87.588  111.637 1.00 94.48  ? 39 VAL B  CA  1 
ATOM   1983 C C   . VAL H 1 39 ? 122.225 86.300  110.898 1.00 97.76  ? 39 VAL B  C   1 
ATOM   1984 O O   . VAL H 1 39 ? 122.555 86.328  109.707 1.00 93.80  ? 39 VAL B  O   1 
ATOM   1985 C CB  . VAL H 1 39 ? 120.629 88.242  111.061 1.00 91.47  ? 39 VAL B  CB  1 
ATOM   1986 C CG1 . VAL H 1 39 ? 119.559 87.195  110.811 1.00 90.96  ? 39 VAL B  CG1 1 
ATOM   1987 C CG2 . VAL H 1 39 ? 120.115 89.312  112.004 1.00 86.64  ? 39 VAL B  CG2 1 
ATOM   1988 N N   . VAL H 1 40 ? 122.138 85.177  111.604 1.00 101.84 ? 40 VAL B  N   1 
ATOM   1989 C CA  . VAL H 1 40 ? 122.364 83.856  111.032 1.00 102.74 ? 40 VAL B  CA  1 
ATOM   1990 C C   . VAL H 1 40 ? 121.084 83.054  111.203 1.00 105.52 ? 40 VAL B  C   1 
ATOM   1991 O O   . VAL H 1 40 ? 120.591 82.895  112.326 1.00 105.13 ? 40 VAL B  O   1 
ATOM   1992 C CB  . VAL H 1 40 ? 123.553 83.140  111.690 1.00 100.19 ? 40 VAL B  CB  1 
ATOM   1993 C CG1 . VAL H 1 40 ? 123.793 81.797  111.026 1.00 98.42  ? 40 VAL B  CG1 1 
ATOM   1994 C CG2 . VAL H 1 40 ? 124.799 84.006  111.615 1.00 97.85  ? 40 VAL B  CG2 1 
ATOM   1995 N N   . ILE H 1 41 ? 120.550 82.549  110.096 1.00 108.51 ? 41 ILE B  N   1 
ATOM   1996 C CA  . ILE H 1 41 ? 119.310 81.783  110.095 1.00 112.67 ? 41 ILE B  CA  1 
ATOM   1997 C C   . ILE H 1 41 ? 119.632 80.338  109.749 1.00 116.23 ? 41 ILE B  C   1 
ATOM   1998 O O   . ILE H 1 41 ? 120.282 80.064  108.732 1.00 115.97 ? 41 ILE B  O   1 
ATOM   1999 C CB  . ILE H 1 41 ? 118.292 82.372  109.106 1.00 112.79 ? 41 ILE B  CB  1 
ATOM   2000 C CG1 . ILE H 1 41 ? 118.132 83.874  109.340 1.00 107.76 ? 41 ILE B  CG1 1 
ATOM   2001 C CG2 . ILE H 1 41 ? 116.953 81.668  109.239 1.00 110.95 ? 41 ILE B  CG2 1 
ATOM   2002 C CD1 . ILE H 1 41 ? 117.275 84.558  108.305 1.00 104.16 ? 41 ILE B  CD1 1 
ATOM   2003 N N   . ALA H 1 42 ? 119.180 79.415  110.591 1.00 118.92 ? 42 ALA B  N   1 
ATOM   2004 C CA  . ALA H 1 42 ? 119.425 77.996  110.373 1.00 121.66 ? 42 ALA B  CA  1 
ATOM   2005 C C   . ALA H 1 42 ? 118.234 77.163  110.835 1.00 127.02 ? 42 ALA B  C   1 
ATOM   2006 O O   . ALA H 1 42 ? 117.356 77.653  111.544 1.00 129.60 ? 42 ALA B  O   1 
ATOM   2007 C CB  . ALA H 1 42 ? 120.690 77.561  111.093 1.00 117.58 ? 42 ALA B  CB  1 
ATOM   2008 O OXT . ALA H 1 42 ? 118.121 75.982  110.509 1.00 127.70 ? 42 ALA B  OXT 1 
ATOM   2009 N N   . GLY I 1 9  ? 135.069 99.751  107.685 1.00 75.58  ? 9  GLY C  N   1 
ATOM   2010 C CA  . GLY I 1 9  ? 134.209 100.427 108.638 1.00 77.59  ? 9  GLY C  CA  1 
ATOM   2011 C C   . GLY I 1 9  ? 132.973 101.028 108.003 1.00 77.76  ? 9  GLY C  C   1 
ATOM   2012 O O   . GLY I 1 9  ? 133.051 101.661 106.952 1.00 78.65  ? 9  GLY C  O   1 
ATOM   2013 N N   . TYR I 1 10 ? 131.826 100.832 108.645 1.00 74.83  ? 10 TYR C  N   1 
ATOM   2014 C CA  . TYR I 1 10 ? 130.549 101.332 108.154 1.00 70.87  ? 10 TYR C  CA  1 
ATOM   2015 C C   . TYR I 1 10 ? 130.126 102.533 108.986 1.00 65.85  ? 10 TYR C  C   1 
ATOM   2016 O O   . TYR I 1 10 ? 130.190 102.492 110.218 1.00 68.66  ? 10 TYR C  O   1 
ATOM   2017 C CB  . TYR I 1 10 ? 129.468 100.250 108.215 1.00 71.13  ? 10 TYR C  CB  1 
ATOM   2018 C CG  . TYR I 1 10 ? 129.765 99.009  107.402 1.00 81.03  ? 10 TYR C  CG  1 
ATOM   2019 C CD1 . TYR I 1 10 ? 130.728 99.017  106.403 1.00 83.11  ? 10 TYR C  CD1 1 
ATOM   2020 C CD2 . TYR I 1 10 ? 129.070 97.830  107.630 1.00 80.21  ? 10 TYR C  CD2 1 
ATOM   2021 C CE1 . TYR I 1 10 ? 130.998 97.883  105.663 1.00 84.09  ? 10 TYR C  CE1 1 
ATOM   2022 C CE2 . TYR I 1 10 ? 129.331 96.693  106.894 1.00 87.12  ? 10 TYR C  CE2 1 
ATOM   2023 C CZ  . TYR I 1 10 ? 130.295 96.725  105.911 1.00 91.17  ? 10 TYR C  CZ  1 
ATOM   2024 O OH  . TYR I 1 10 ? 130.559 95.594  105.174 1.00 91.09  ? 10 TYR C  OH  1 
ATOM   2025 N N   . GLU I 1 11 ? 129.702 103.597 108.313 1.00 61.80  ? 11 GLU C  N   1 
ATOM   2026 C CA  . GLU I 1 11 ? 129.199 104.801 108.970 1.00 57.88  ? 11 GLU C  CA  1 
ATOM   2027 C C   . GLU I 1 11 ? 127.812 105.089 108.410 1.00 52.72  ? 11 GLU C  C   1 
ATOM   2028 O O   . GLU I 1 11 ? 127.679 105.686 107.338 1.00 58.89  ? 11 GLU C  O   1 
ATOM   2029 C CB  . GLU I 1 11 ? 130.141 105.980 108.761 1.00 61.88  ? 11 GLU C  CB  1 
ATOM   2030 C CG  . GLU I 1 11 ? 129.994 107.069 109.806 1.00 65.71  ? 11 GLU C  CG  1 
ATOM   2031 C CD  . GLU I 1 11 ? 130.754 108.327 109.444 1.00 76.41  ? 11 GLU C  CD  1 
ATOM   2032 O OE1 . GLU I 1 11 ? 131.968 108.232 109.170 1.00 81.59  ? 11 GLU C  OE1 1 
ATOM   2033 O OE2 . GLU I 1 11 ? 130.138 109.413 109.439 1.00 75.54  ? 11 GLU C  OE2 1 
ATOM   2034 N N   . VAL I 1 12 ? 126.783 104.666 109.135 1.00 47.56  ? 12 VAL C  N   1 
ATOM   2035 C CA  . VAL I 1 12 ? 125.395 104.829 108.725 1.00 41.82  ? 12 VAL C  CA  1 
ATOM   2036 C C   . VAL I 1 12 ? 124.750 105.834 109.666 1.00 43.59  ? 12 VAL C  C   1 
ATOM   2037 O O   . VAL I 1 12 ? 124.787 105.656 110.889 1.00 54.65  ? 12 VAL C  O   1 
ATOM   2038 C CB  . VAL I 1 12 ? 124.645 103.490 108.750 1.00 38.02  ? 12 VAL C  CB  1 
ATOM   2039 C CG1 . VAL I 1 12 ? 123.254 103.646 108.178 1.00 36.81  ? 12 VAL C  CG1 1 
ATOM   2040 C CG2 . VAL I 1 12 ? 125.424 102.437 107.989 1.00 37.82  ? 12 VAL C  CG2 1 
ATOM   2041 N N   . HIS I 1 13 ? 124.163 106.892 109.111 1.00 39.40  ? 13 HIS C  N   1 
ATOM   2042 C CA  . HIS I 1 13 ? 123.505 107.877 109.955 1.00 42.52  ? 13 HIS C  CA  1 
ATOM   2043 C C   . HIS I 1 13 ? 122.396 108.579 109.188 1.00 39.69  ? 13 HIS C  C   1 
ATOM   2044 O O   . HIS I 1 13 ? 122.309 108.495 107.965 1.00 38.87  ? 13 HIS C  O   1 
ATOM   2045 C CB  . HIS I 1 13 ? 124.492 108.907 110.523 1.00 45.91  ? 13 HIS C  CB  1 
ATOM   2046 C CG  . HIS I 1 13 ? 125.493 109.417 109.534 1.00 46.41  ? 13 HIS C  CG  1 
ATOM   2047 N ND1 . HIS I 1 13 ? 125.549 110.739 109.153 1.00 43.92  ? 13 HIS C  ND1 1 
ATOM   2048 C CD2 . HIS I 1 13 ? 126.501 108.794 108.880 1.00 49.27  ? 13 HIS C  CD2 1 
ATOM   2049 C CE1 . HIS I 1 13 ? 126.534 110.905 108.290 1.00 48.42  ? 13 HIS C  CE1 1 
ATOM   2050 N NE2 . HIS I 1 13 ? 127.127 109.740 108.107 1.00 50.84  ? 13 HIS C  NE2 1 
ATOM   2051 N N   . HIS I 1 14 ? 121.525 109.249 109.942 1.00 39.43  ? 14 HIS C  N   1 
ATOM   2052 C CA  . HIS I 1 14 ? 120.452 110.084 109.401 1.00 36.41  ? 14 HIS C  CA  1 
ATOM   2053 C C   . HIS I 1 14 ? 119.529 109.289 108.476 1.00 34.91  ? 14 HIS C  C   1 
ATOM   2054 O O   . HIS I 1 14 ? 119.421 109.553 107.283 1.00 41.49  ? 14 HIS C  O   1 
ATOM   2055 C CB  . HIS I 1 14 ? 121.026 111.312 108.693 1.00 37.87  ? 14 HIS C  CB  1 
ATOM   2056 C CG  . HIS I 1 14 ? 121.698 112.273 109.620 1.00 43.65  ? 14 HIS C  CG  1 
ATOM   2057 N ND1 . HIS I 1 14 ? 123.041 112.204 109.917 1.00 45.90  ? 14 HIS C  ND1 1 
ATOM   2058 C CD2 . HIS I 1 14 ? 121.206 113.311 110.336 1.00 47.98  ? 14 HIS C  CD2 1 
ATOM   2059 C CE1 . HIS I 1 14 ? 123.351 113.167 110.766 1.00 53.85  ? 14 HIS C  CE1 1 
ATOM   2060 N NE2 . HIS I 1 14 ? 122.256 113.853 111.036 1.00 57.15  ? 14 HIS C  NE2 1 
ATOM   2061 N N   . GLN I 1 15 ? 118.850 108.307 109.057 1.00 31.09  ? 15 GLN C  N   1 
ATOM   2062 C CA  . GLN I 1 15 ? 117.887 107.487 108.336 1.00 25.82  ? 15 GLN C  CA  1 
ATOM   2063 C C   . GLN I 1 15 ? 116.505 107.684 108.935 1.00 27.11  ? 15 GLN C  C   1 
ATOM   2064 O O   . GLN I 1 15 ? 116.339 107.615 110.155 1.00 36.68  ? 15 GLN C  O   1 
ATOM   2065 C CB  . GLN I 1 15 ? 118.273 106.011 108.386 1.00 26.86  ? 15 GLN C  CB  1 
ATOM   2066 C CG  . GLN I 1 15 ? 119.030 105.540 107.171 1.00 36.02  ? 15 GLN C  CG  1 
ATOM   2067 C CD  . GLN I 1 15 ? 120.518 105.691 107.336 1.00 36.75  ? 15 GLN C  CD  1 
ATOM   2068 O OE1 . GLN I 1 15 ? 121.008 105.908 108.441 1.00 32.60  ? 15 GLN C  OE1 1 
ATOM   2069 N NE2 . GLN I 1 15 ? 121.250 105.584 106.237 1.00 36.88  ? 15 GLN C  NE2 1 
ATOM   2070 N N   . LYS I 1 16 ? 115.522 107.931 108.079 1.00 25.46  ? 16 LYS C  N   1 
ATOM   2071 C CA  . LYS I 1 16 ? 114.119 108.000 108.478 1.00 23.75  ? 16 LYS C  CA  1 
ATOM   2072 C C   . LYS I 1 16 ? 113.405 106.842 107.794 1.00 27.50  ? 16 LYS C  C   1 
ATOM   2073 O O   . LYS I 1 16 ? 113.083 106.919 106.605 1.00 37.91  ? 16 LYS C  O   1 
ATOM   2074 C CB  . LYS I 1 16 ? 113.499 109.338 108.104 1.00 23.54  ? 16 LYS C  CB  1 
ATOM   2075 C CG  . LYS I 1 16 ? 114.222 110.527 108.681 1.00 20.89  ? 16 LYS C  CG  1 
ATOM   2076 C CD  . LYS I 1 16 ? 113.455 111.798 108.417 1.00 22.06  ? 16 LYS C  CD  1 
ATOM   2077 C CE  . LYS I 1 16 ? 114.143 112.985 109.047 1.00 22.83  ? 16 LYS C  CE  1 
ATOM   2078 N NZ  . LYS I 1 16 ? 113.241 114.159 109.074 1.00 28.31  ? 16 LYS C  NZ  1 
ATOM   2079 N N   . LEU I 1 17 ? 113.158 105.773 108.541 1.00 23.96  ? 17 LEU C  N   1 
ATOM   2080 C CA  . LEU I 1 17 ? 112.609 104.543 107.993 1.00 25.08  ? 17 LEU C  CA  1 
ATOM   2081 C C   . LEU I 1 17 ? 111.225 104.296 108.572 1.00 25.06  ? 17 LEU C  C   1 
ATOM   2082 O O   . LEU I 1 17 ? 111.036 104.369 109.788 1.00 32.20  ? 17 LEU C  O   1 
ATOM   2083 C CB  . LEU I 1 17 ? 113.527 103.359 108.296 1.00 25.85  ? 17 LEU C  CB  1 
ATOM   2084 C CG  . LEU I 1 17 ? 113.298 102.085 107.489 1.00 28.96  ? 17 LEU C  CG  1 
ATOM   2085 C CD1 . LEU I 1 17 ? 114.627 101.514 107.046 1.00 37.70  ? 17 LEU C  CD1 1 
ATOM   2086 C CD2 . LEU I 1 17 ? 112.521 101.064 108.297 1.00 27.85  ? 17 LEU C  CD2 1 
ATOM   2087 N N   . VAL I 1 18 ? 110.263 104.013 107.700 1.00 24.89  ? 18 VAL C  N   1 
ATOM   2088 C CA  . VAL I 1 18 ? 108.930 103.584 108.099 1.00 26.58  ? 18 VAL C  CA  1 
ATOM   2089 C C   . VAL I 1 18 ? 108.671 102.225 107.470 1.00 29.85  ? 18 VAL C  C   1 
ATOM   2090 O O   . VAL I 1 18 ? 108.815 102.062 106.254 1.00 35.03  ? 18 VAL C  O   1 
ATOM   2091 C CB  . VAL I 1 18 ? 107.848 104.596 107.686 1.00 25.75  ? 18 VAL C  CB  1 
ATOM   2092 C CG1 . VAL I 1 18 ? 106.551 104.282 108.392 1.00 24.22  ? 18 VAL C  CG1 1 
ATOM   2093 C CG2 . VAL I 1 18 ? 108.293 106.005 108.008 1.00 24.63  ? 18 VAL C  CG2 1 
ATOM   2094 N N   . PHE I 1 19 ? 108.294 101.255 108.295 1.00 30.43  ? 19 PHE C  N   1 
ATOM   2095 C CA  . PHE I 1 19 ? 108.127 99.873  107.868 1.00 32.79  ? 19 PHE C  CA  1 
ATOM   2096 C C   . PHE I 1 19 ? 106.711 99.424  108.190 1.00 36.31  ? 19 PHE C  C   1 
ATOM   2097 O O   . PHE I 1 19 ? 106.325 99.372  109.361 1.00 43.04  ? 19 PHE C  O   1 
ATOM   2098 C CB  . PHE I 1 19 ? 109.151 98.972  108.559 1.00 36.08  ? 19 PHE C  CB  1 
ATOM   2099 C CG  . PHE I 1 19 ? 109.338 97.641  107.898 1.00 38.70  ? 19 PHE C  CG  1 
ATOM   2100 C CD1 . PHE I 1 19 ? 108.391 96.643  108.036 1.00 38.82  ? 19 PHE C  CD1 1 
ATOM   2101 C CD2 . PHE I 1 19 ? 110.470 97.381  107.152 1.00 41.78  ? 19 PHE C  CD2 1 
ATOM   2102 C CE1 . PHE I 1 19 ? 108.564 95.418  107.434 1.00 39.93  ? 19 PHE C  CE1 1 
ATOM   2103 C CE2 . PHE I 1 19 ? 110.648 96.156  106.548 1.00 44.10  ? 19 PHE C  CE2 1 
ATOM   2104 C CZ  . PHE I 1 19 ? 109.695 95.174  106.690 1.00 44.51  ? 19 PHE C  CZ  1 
ATOM   2105 N N   . PHE I 1 20 ? 105.944 99.098  107.156 1.00 35.86  ? 20 PHE C  N   1 
ATOM   2106 C CA  . PHE I 1 20 ? 104.609 98.539  107.305 1.00 37.59  ? 20 PHE C  CA  1 
ATOM   2107 C C   . PHE I 1 20 ? 104.652 97.062  106.949 1.00 45.25  ? 20 PHE C  C   1 
ATOM   2108 O O   . PHE I 1 20 ? 105.205 96.688  105.911 1.00 55.23  ? 20 PHE C  O   1 
ATOM   2109 C CB  . PHE I 1 20 ? 103.598 99.253  106.407 1.00 39.09  ? 20 PHE C  CB  1 
ATOM   2110 C CG  . PHE I 1 20 ? 103.334 100.675 106.793 1.00 38.58  ? 20 PHE C  CG  1 
ATOM   2111 C CD1 . PHE I 1 20 ? 104.094 101.700 106.267 1.00 36.65  ? 20 PHE C  CD1 1 
ATOM   2112 C CD2 . PHE I 1 20 ? 102.309 100.990 107.663 1.00 35.18  ? 20 PHE C  CD2 1 
ATOM   2113 C CE1 . PHE I 1 20 ? 103.845 103.008 106.610 1.00 33.87  ? 20 PHE C  CE1 1 
ATOM   2114 C CE2 . PHE I 1 20 ? 102.057 102.298 108.010 1.00 34.77  ? 20 PHE C  CE2 1 
ATOM   2115 C CZ  . PHE I 1 20 ? 102.826 103.307 107.483 1.00 31.87  ? 20 PHE C  CZ  1 
ATOM   2116 N N   . ALA I 1 21 ? 104.076 96.229  107.806 1.00 46.71  ? 21 ALA C  N   1 
ATOM   2117 C CA  . ALA I 1 21 ? 103.979 94.800  107.553 1.00 51.62  ? 21 ALA C  CA  1 
ATOM   2118 C C   . ALA I 1 21 ? 102.561 94.338  107.838 1.00 59.08  ? 21 ALA C  C   1 
ATOM   2119 O O   . ALA I 1 21 ? 101.951 94.752  108.827 1.00 64.50  ? 21 ALA C  O   1 
ATOM   2120 C CB  . ALA I 1 21 ? 104.974 94.011  108.406 1.00 47.68  ? 21 ALA C  CB  1 
ATOM   2121 N N   . GLU I 1 22 ? 102.036 93.488  106.965 1.00 62.23  ? 22 GLU C  N   1 
ATOM   2122 C CA  . GLU I 1 22 ? 100.697 92.947  107.146 1.00 69.45  ? 22 GLU C  CA  1 
ATOM   2123 C C   . GLU I 1 22 ? 100.692 91.442  106.941 1.00 74.34  ? 22 GLU C  C   1 
ATOM   2124 O O   . GLU I 1 22 ? 101.475 90.911  106.157 1.00 78.12  ? 22 GLU C  O   1 
ATOM   2125 C CB  . GLU I 1 22 ? 99.712  93.610  106.188 1.00 72.05  ? 22 GLU C  CB  1 
ATOM   2126 C CG  . GLU I 1 22 ? 99.205  94.951  106.666 1.00 71.84  ? 22 GLU C  CG  1 
ATOM   2127 C CD  . GLU I 1 22 ? 97.754  94.902  107.096 1.00 75.14  ? 22 GLU C  CD  1 
ATOM   2128 O OE1 . GLU I 1 22 ? 97.207  93.785  107.212 1.00 75.71  ? 22 GLU C  OE1 1 
ATOM   2129 O OE2 . GLU I 1 22 ? 97.160  95.978  107.317 1.00 74.25  ? 22 GLU C  OE2 1 
HETATM 2130 N N   . DAS I 1 23 ? 99.801  90.758  107.649 1.00 72.71  ? 23 DAS C  N   1 
HETATM 2131 C CA  . DAS I 1 23 ? 99.726  89.309  107.578 1.00 76.75  ? 23 DAS C  CA  1 
HETATM 2132 C C   . DAS I 1 23 ? 100.946 88.707  108.260 1.00 76.02  ? 23 DAS C  C   1 
HETATM 2133 O O   . DAS I 1 23 ? 100.953 88.519  109.476 1.00 76.84  ? 23 DAS C  O   1 
HETATM 2134 C CB  . DAS I 1 23 ? 98.445  88.812  108.247 1.00 83.90  ? 23 DAS C  CB  1 
HETATM 2135 C CG  . DAS I 1 23 ? 98.183  87.342  107.988 1.00 88.14  ? 23 DAS C  CG  1 
HETATM 2136 O OD1 . DAS I 1 23 ? 98.911  86.738  107.172 1.00 87.21  ? 23 DAS C  OD1 1 
HETATM 2137 O OD2 . DAS I 1 23 ? 97.247  86.788  108.602 1.00 86.54  ? 23 DAS C  OD2 1 
ATOM   2138 N N   . VAL I 1 24 ? 101.975 88.421  107.466 1.00 73.27  ? 24 VAL C  N   1 
ATOM   2139 C CA  . VAL I 1 24 ? 103.223 87.838  107.953 1.00 69.90  ? 24 VAL C  CA  1 
ATOM   2140 C C   . VAL I 1 24 ? 102.958 86.598  108.800 1.00 67.77  ? 24 VAL C  C   1 
ATOM   2141 O O   . VAL I 1 24 ? 103.156 86.607  110.012 1.00 70.39  ? 24 VAL C  O   1 
ATOM   2142 C CB  . VAL I 1 24 ? 104.047 88.870  108.742 1.00 64.79  ? 24 VAL C  CB  1 
ATOM   2143 C CG1 . VAL I 1 24 ? 105.462 88.368  108.944 1.00 56.42  ? 24 VAL C  CG1 1 
ATOM   2144 C CG2 . VAL I 1 24 ? 104.061 90.202  108.018 1.00 58.59  ? 24 VAL C  CG2 1 
ATOM   2145 N N   . GLY I 1 25 ? 102.504 85.526  108.156 1.00 65.16  ? 25 GLY C  N   1 
ATOM   2146 C CA  . GLY I 1 25 ? 102.167 84.297  108.849 1.00 63.72  ? 25 GLY C  CA  1 
ATOM   2147 C C   . GLY I 1 25 ? 103.272 83.267  108.709 1.00 65.69  ? 25 GLY C  C   1 
ATOM   2148 O O   . GLY I 1 25 ? 103.814 83.063  107.621 1.00 67.63  ? 25 GLY C  O   1 
ATOM   2149 N N   . SER I 1 26 ? 103.596 82.621  109.830 1.00 66.41  ? 26 SER C  N   1 
ATOM   2150 C CA  . SER I 1 26 ? 104.567 81.528  109.869 1.00 66.74  ? 26 SER C  CA  1 
ATOM   2151 C C   . SER I 1 26 ? 105.913 81.952  109.286 1.00 62.57  ? 26 SER C  C   1 
ATOM   2152 O O   . SER I 1 26 ? 106.532 81.233  108.499 1.00 59.58  ? 26 SER C  O   1 
ATOM   2153 C CB  . SER I 1 26 ? 104.022 80.292  109.150 1.00 65.12  ? 26 SER C  CB  1 
ATOM   2154 O OG  . SER I 1 26 ? 102.623 80.170  109.338 1.00 62.29  ? 26 SER C  OG  1 
ATOM   2155 N N   . ASN I 1 27 ? 106.368 83.137  109.680 1.00 58.74  ? 27 ASN C  N   1 
ATOM   2156 C CA  . ASN I 1 27 ? 107.662 83.629  109.231 1.00 53.96  ? 27 ASN C  CA  1 
ATOM   2157 C C   . ASN I 1 27 ? 108.777 82.839  109.903 1.00 54.07  ? 27 ASN C  C   1 
ATOM   2158 O O   . ASN I 1 27 ? 108.872 82.811  111.134 1.00 61.28  ? 27 ASN C  O   1 
ATOM   2159 C CB  . ASN I 1 27 ? 107.800 85.117  109.539 1.00 53.66  ? 27 ASN C  CB  1 
ATOM   2160 C CG  . ASN I 1 27 ? 109.245 85.570  109.582 1.00 48.69  ? 27 ASN C  CG  1 
ATOM   2161 O OD1 . ASN I 1 27 ? 109.981 85.429  108.609 1.00 46.96  ? 27 ASN C  OD1 1 
ATOM   2162 N ND2 . ASN I 1 27 ? 109.659 86.117  110.716 1.00 48.76  ? 27 ASN C  ND2 1 
ATOM   2163 N N   . LYS I 1 28 ? 109.617 82.194  109.098 1.00 49.39  ? 28 LYS C  N   1 
ATOM   2164 C CA  . LYS I 1 28 ? 110.772 81.466  109.599 1.00 50.70  ? 28 LYS C  CA  1 
ATOM   2165 C C   . LYS I 1 28 ? 112.086 82.164  109.293 1.00 50.43  ? 28 LYS C  C   1 
ATOM   2166 O O   . LYS I 1 28 ? 113.147 81.646  109.654 1.00 47.12  ? 28 LYS C  O   1 
ATOM   2167 C CB  . LYS I 1 28 ? 110.794 80.046  109.024 1.00 51.94  ? 28 LYS C  CB  1 
ATOM   2168 C CG  . LYS I 1 28 ? 109.500 79.283  109.228 1.00 54.88  ? 28 LYS C  CG  1 
ATOM   2169 C CD  . LYS I 1 28 ? 109.740 77.785  109.241 1.00 56.29  ? 28 LYS C  CD  1 
ATOM   2170 C CE  . LYS I 1 28 ? 108.431 77.019  109.293 1.00 61.55  ? 28 LYS C  CE  1 
ATOM   2171 N NZ  . LYS I 1 28 ? 107.253 77.929  109.289 1.00 55.99  ? 28 LYS C  NZ  1 
ATOM   2172 N N   . GLY I 1 29 ? 112.047 83.323  108.635 1.00 54.52  ? 29 GLY C  N   1 
ATOM   2173 C CA  . GLY I 1 29 ? 113.225 84.080  108.314 1.00 50.66  ? 29 GLY C  CA  1 
ATOM   2174 C C   . GLY I 1 29 ? 113.338 85.352  109.126 1.00 49.00  ? 29 GLY C  C   1 
ATOM   2175 O O   . GLY I 1 29 ? 112.683 85.528  110.161 1.00 48.69  ? 29 GLY C  O   1 
ATOM   2176 N N   . ALA I 1 30 ? 114.177 86.261  108.642 1.00 48.30  ? 30 ALA C  N   1 
ATOM   2177 C CA  . ALA I 1 30 ? 114.437 87.530  109.309 1.00 41.05  ? 30 ALA C  CA  1 
ATOM   2178 C C   . ALA I 1 30 ? 113.711 88.644  108.569 1.00 40.65  ? 30 ALA C  C   1 
ATOM   2179 O O   . ALA I 1 30 ? 113.897 88.814  107.361 1.00 43.98  ? 30 ALA C  O   1 
ATOM   2180 C CB  . ALA I 1 30 ? 115.936 87.816  109.370 1.00 35.72  ? 30 ALA C  CB  1 
ATOM   2181 N N   . ILE I 1 31 ? 112.892 89.397  109.293 1.00 38.51  ? 31 ILE C  N   1 
ATOM   2182 C CA  . ILE I 1 31 ? 112.220 90.578  108.766 1.00 37.05  ? 31 ILE C  CA  1 
ATOM   2183 C C   . ILE I 1 31 ? 112.767 91.776  109.523 1.00 40.18  ? 31 ILE C  C   1 
ATOM   2184 O O   . ILE I 1 31 ? 112.436 91.985  110.696 1.00 49.66  ? 31 ILE C  O   1 
ATOM   2185 C CB  . ILE I 1 31 ? 110.697 90.479  108.903 1.00 33.50  ? 31 ILE C  CB  1 
ATOM   2186 C CG1 . ILE I 1 31 ? 110.182 89.268  108.131 1.00 38.10  ? 31 ILE C  CG1 1 
ATOM   2187 C CG2 . ILE I 1 31 ? 110.036 91.755  108.416 1.00 30.82  ? 31 ILE C  CG2 1 
ATOM   2188 C CD1 . ILE I 1 31 ? 108.701 89.277  107.912 1.00 42.08  ? 31 ILE C  CD1 1 
ATOM   2189 N N   . ILE I 1 32 ? 113.605 92.566  108.860 1.00 37.80  ? 32 ILE C  N   1 
ATOM   2190 C CA  . ILE I 1 32 ? 114.336 93.652  109.498 1.00 42.84  ? 32 ILE C  CA  1 
ATOM   2191 C C   . ILE I 1 32 ? 114.003 94.956  108.793 1.00 42.30  ? 32 ILE C  C   1 
ATOM   2192 O O   . ILE I 1 32 ? 113.928 95.006  107.562 1.00 45.16  ? 32 ILE C  O   1 
ATOM   2193 C CB  . ILE I 1 32 ? 115.856 93.395  109.484 1.00 44.85  ? 32 ILE C  CB  1 
ATOM   2194 C CG1 . ILE I 1 32 ? 116.162 91.984  109.983 1.00 42.64  ? 32 ILE C  CG1 1 
ATOM   2195 C CG2 . ILE I 1 32 ? 116.573 94.414  110.341 1.00 48.55  ? 32 ILE C  CG2 1 
ATOM   2196 C CD1 . ILE I 1 32 ? 117.261 91.291  109.219 1.00 40.67  ? 32 ILE C  CD1 1 
ATOM   2197 N N   . GLY I 1 33 ? 113.788 96.008  109.575 1.00 44.70  ? 33 GLY C  N   1 
ATOM   2198 C CA  . GLY I 1 33 ? 113.570 97.324  109.012 1.00 40.70  ? 33 GLY C  CA  1 
ATOM   2199 C C   . GLY I 1 33 ? 114.855 97.934  108.495 1.00 40.23  ? 33 GLY C  C   1 
ATOM   2200 O O   . GLY I 1 33 ? 114.975 98.232  107.305 1.00 43.73  ? 33 GLY C  O   1 
ATOM   2201 N N   . LEU I 1 34 ? 115.824 98.130  109.384 1.00 41.37  ? 34 LEU C  N   1 
ATOM   2202 C CA  . LEU I 1 34 ? 117.149 98.610  109.014 1.00 41.56  ? 34 LEU C  CA  1 
ATOM   2203 C C   . LEU I 1 34 ? 118.172 97.645  109.587 1.00 43.59  ? 34 LEU C  C   1 
ATOM   2204 O O   . LEU I 1 34 ? 118.195 97.414  110.799 1.00 52.62  ? 34 LEU C  O   1 
ATOM   2205 C CB  . LEU I 1 34 ? 117.396 100.026 109.536 1.00 42.98  ? 34 LEU C  CB  1 
ATOM   2206 C CG  . LEU I 1 34 ? 118.573 100.785 108.923 1.00 39.98  ? 34 LEU C  CG  1 
ATOM   2207 C CD1 . LEU I 1 34 ? 118.145 102.189 108.540 1.00 33.09  ? 34 LEU C  CD1 1 
ATOM   2208 C CD2 . LEU I 1 34 ? 119.760 100.821 109.864 1.00 40.03  ? 34 LEU C  CD2 1 
ATOM   2209 N N   . MET I 1 35 ? 119.015 97.088  108.727 1.00 38.84  ? 35 MET C  N   1 
ATOM   2210 C CA  . MET I 1 35 ? 120.021 96.120  109.136 1.00 44.10  ? 35 MET C  CA  1 
ATOM   2211 C C   . MET I 1 35 ? 121.392 96.600  108.687 1.00 48.26  ? 35 MET C  C   1 
ATOM   2212 O O   . MET I 1 35 ? 121.581 96.937  107.515 1.00 57.64  ? 35 MET C  O   1 
ATOM   2213 C CB  . MET I 1 35 ? 119.726 94.741  108.549 1.00 46.59  ? 35 MET C  CB  1 
ATOM   2214 C CG  . MET I 1 35 ? 120.920 93.813  108.543 1.00 51.67  ? 35 MET C  CG  1 
ATOM   2215 S SD  . MET I 1 35 ? 120.984 92.734  109.975 1.00 73.51  ? 35 MET C  SD  1 
ATOM   2216 C CE  . MET I 1 35 ? 122.671 92.151  109.882 1.00 71.03  ? 35 MET C  CE  1 
ATOM   2217 N N   . VAL I 1 36 ? 122.340 96.635  109.617 1.00 48.97  ? 36 VAL C  N   1 
ATOM   2218 C CA  . VAL I 1 36 ? 123.726 96.974  109.325 1.00 50.21  ? 36 VAL C  CA  1 
ATOM   2219 C C   . VAL I 1 36 ? 124.591 95.820  109.804 1.00 56.88  ? 36 VAL C  C   1 
ATOM   2220 O O   . VAL I 1 36 ? 124.495 95.407  110.966 1.00 64.00  ? 36 VAL C  O   1 
ATOM   2221 C CB  . VAL I 1 36 ? 124.150 98.291  109.992 1.00 46.62  ? 36 VAL C  CB  1 
ATOM   2222 C CG1 . VAL I 1 36 ? 125.617 98.568  109.721 1.00 48.09  ? 36 VAL C  CG1 1 
ATOM   2223 C CG2 . VAL I 1 36 ? 123.287 99.436  109.497 1.00 41.47  ? 36 VAL C  CG2 1 
ATOM   2224 N N   . GLY I 1 37 ? 125.432 95.301  108.917 1.00 56.15  ? 37 GLY C  N   1 
ATOM   2225 C CA  . GLY I 1 37 ? 126.259 94.162  109.256 1.00 61.50  ? 37 GLY C  CA  1 
ATOM   2226 C C   . GLY I 1 37 ? 126.267 93.096  108.184 1.00 74.49  ? 37 GLY C  C   1 
ATOM   2227 O O   . GLY I 1 37 ? 126.705 93.345  107.058 1.00 81.43  ? 37 GLY C  O   1 
ATOM   2228 N N   . GLY I 1 38 ? 125.796 91.904  108.517 1.00 77.39  ? 38 GLY C  N   1 
ATOM   2229 C CA  . GLY I 1 38 ? 125.768 90.814  107.559 1.00 82.98  ? 38 GLY C  CA  1 
ATOM   2230 C C   . GLY I 1 38 ? 124.638 89.859  107.856 1.00 87.96  ? 38 GLY C  C   1 
ATOM   2231 O O   . GLY I 1 38 ? 124.363 89.535  109.015 1.00 86.27  ? 38 GLY C  O   1 
ATOM   2232 N N   . VAL I 1 39 ? 123.983 89.399  106.795 1.00 90.26  ? 39 VAL C  N   1 
ATOM   2233 C CA  . VAL I 1 39 ? 122.879 88.453  106.890 1.00 94.48  ? 39 VAL C  CA  1 
ATOM   2234 C C   . VAL I 1 39 ? 123.273 87.184  106.150 1.00 97.76  ? 39 VAL C  C   1 
ATOM   2235 O O   . VAL I 1 39 ? 123.600 87.231  104.959 1.00 93.80  ? 39 VAL C  O   1 
ATOM   2236 C CB  . VAL I 1 39 ? 121.576 89.039  106.316 1.00 91.47  ? 39 VAL C  CB  1 
ATOM   2237 C CG1 . VAL I 1 39 ? 120.563 87.936  106.066 1.00 90.96  ? 39 VAL C  CG1 1 
ATOM   2238 C CG2 . VAL I 1 39 ? 121.007 90.080  107.260 1.00 86.64  ? 39 VAL C  CG2 1 
ATOM   2239 N N   . VAL I 1 40 ? 123.247 86.058  106.856 1.00 101.84 ? 40 VAL C  N   1 
ATOM   2240 C CA  . VAL I 1 40 ? 123.543 84.752  106.283 1.00 102.74 ? 40 VAL C  CA  1 
ATOM   2241 C C   . VAL I 1 40 ? 122.308 83.882  106.455 1.00 105.52 ? 40 VAL C  C   1 
ATOM   2242 O O   . VAL I 1 40 ? 121.824 83.697  107.578 1.00 105.13 ? 40 VAL C  O   1 
ATOM   2243 C CB  . VAL I 1 40 ? 124.769 84.100  106.940 1.00 100.19 ? 40 VAL C  CB  1 
ATOM   2244 C CG1 . VAL I 1 40 ? 125.079 82.771  106.274 1.00 98.42  ? 40 VAL C  CG1 1 
ATOM   2245 C CG2 . VAL I 1 40 ? 125.967 85.031  106.863 1.00 97.85  ? 40 VAL C  CG2 1 
ATOM   2246 N N   . ILE I 1 41 ? 121.800 83.350  105.348 1.00 108.51 ? 41 ILE C  N   1 
ATOM   2247 C CA  . ILE I 1 41 ? 120.603 82.519  105.349 1.00 112.67 ? 41 ILE C  CA  1 
ATOM   2248 C C   . ILE I 1 41 ? 121.001 81.093  105.001 1.00 116.23 ? 41 ILE C  C   1 
ATOM   2249 O O   . ILE I 1 41 ? 121.664 80.855  103.983 1.00 115.97 ? 41 ILE C  O   1 
ATOM   2250 C CB  . ILE I 1 41 ? 119.554 83.054  104.360 1.00 112.79 ? 41 ILE C  CB  1 
ATOM   2251 C CG1 . ILE I 1 41 ? 119.314 84.544  104.596 1.00 107.76 ? 41 ILE C  CG1 1 
ATOM   2252 C CG2 . ILE I 1 41 ? 118.254 82.279  104.494 1.00 110.95 ? 41 ILE C  CG2 1 
ATOM   2253 C CD1 . ILE I 1 41 ? 118.421 85.182  103.561 1.00 104.16 ? 41 ILE C  CD1 1 
ATOM   2254 N N   . ALA I 1 42 ? 120.600 80.147  105.843 1.00 118.92 ? 42 ALA C  N   1 
ATOM   2255 C CA  . ALA I 1 42 ? 120.920 78.743  105.624 1.00 121.66 ? 42 ALA C  CA  1 
ATOM   2256 C C   . ALA I 1 42 ? 119.776 77.848  106.087 1.00 127.02 ? 42 ALA C  C   1 
ATOM   2257 O O   . ALA I 1 42 ? 118.873 78.290  106.797 1.00 129.60 ? 42 ALA C  O   1 
ATOM   2258 C CB  . ALA I 1 42 ? 122.207 78.376  106.343 1.00 117.58 ? 42 ALA C  CB  1 
ATOM   2259 O OXT . ALA I 1 42 ? 119.725 76.662  105.761 1.00 127.70 ? 42 ALA C  OXT 1 
ATOM   2260 N N   . GLY J 1 9  ? 135.369 101.337 102.926 1.00 75.58  ? 9  GLY D  N   1 
ATOM   2261 C CA  . GLY J 1 9  ? 134.474 101.966 103.879 1.00 77.59  ? 9  GLY D  CA  1 
ATOM   2262 C C   . GLY J 1 9  ? 133.206 102.498 103.243 1.00 77.76  ? 9  GLY D  C   1 
ATOM   2263 O O   . GLY J 1 9  ? 133.249 103.132 102.191 1.00 78.65  ? 9  GLY D  O   1 
ATOM   2264 N N   . TYR J 1 10 ? 132.072 102.239 103.886 1.00 74.83  ? 10 TYR D  N   1 
ATOM   2265 C CA  . TYR J 1 10 ? 130.769 102.667 103.395 1.00 70.87  ? 10 TYR D  CA  1 
ATOM   2266 C C   . TYR J 1 10 ? 130.282 103.844 104.226 1.00 65.85  ? 10 TYR D  C   1 
ATOM   2267 O O   . TYR J 1 10 ? 130.348 103.808 105.458 1.00 68.66  ? 10 TYR D  O   1 
ATOM   2268 C CB  . TYR J 1 10 ? 129.750 101.528 103.458 1.00 71.13  ? 10 TYR D  CB  1 
ATOM   2269 C CG  . TYR J 1 10 ? 130.114 100.304 102.647 1.00 81.03  ? 10 TYR D  CG  1 
ATOM   2270 C CD1 . TYR J 1 10 ? 131.075 100.363 101.647 1.00 83.11  ? 10 TYR D  CD1 1 
ATOM   2271 C CD2 . TYR J 1 10 ? 129.485 99.089  102.877 1.00 80.21  ? 10 TYR D  CD2 1 
ATOM   2272 C CE1 . TYR J 1 10 ? 131.407 99.245  100.909 1.00 84.09  ? 10 TYR D  CE1 1 
ATOM   2273 C CE2 . TYR J 1 10 ? 129.809 97.967  102.142 1.00 87.12  ? 10 TYR D  CE2 1 
ATOM   2274 C CZ  . TYR J 1 10 ? 130.769 98.050  101.159 1.00 91.17  ? 10 TYR D  CZ  1 
ATOM   2275 O OH  . TYR J 1 10 ? 131.094 96.935  100.423 1.00 91.09  ? 10 TYR D  OH  1 
ATOM   2276 N N   . GLU J 1 11 ? 129.799 104.883 103.552 1.00 61.80  ? 11 GLU D  N   1 
ATOM   2277 C CA  . GLU J 1 11 ? 129.231 106.058 104.207 1.00 57.88  ? 11 GLU D  CA  1 
ATOM   2278 C C   . GLU J 1 11 ? 127.830 106.268 103.647 1.00 52.72  ? 11 GLU D  C   1 
ATOM   2279 O O   . GLU J 1 11 ? 127.664 106.856 102.575 1.00 58.89  ? 11 GLU D  O   1 
ATOM   2280 C CB  . GLU J 1 11 ? 130.106 107.287 103.996 1.00 61.88  ? 11 GLU D  CB  1 
ATOM   2281 C CG  . GLU J 1 11 ? 129.901 108.368 105.039 1.00 65.71  ? 11 GLU D  CG  1 
ATOM   2282 C CD  . GLU J 1 11 ? 130.589 109.665 104.676 1.00 76.41  ? 11 GLU D  CD  1 
ATOM   2283 O OE1 . GLU J 1 11 ? 131.807 109.637 104.401 1.00 81.59  ? 11 GLU D  OE1 1 
ATOM   2284 O OE2 . GLU J 1 11 ? 129.914 110.716 104.669 1.00 75.54  ? 11 GLU D  OE2 1 
ATOM   2285 N N   . VAL J 1 12 ? 126.826 105.790 104.374 1.00 47.56  ? 12 VAL D  N   1 
ATOM   2286 C CA  . VAL J 1 12 ? 125.431 105.876 103.965 1.00 41.82  ? 12 VAL D  CA  1 
ATOM   2287 C C   . VAL J 1 12 ? 124.732 106.845 104.905 1.00 43.59  ? 12 VAL D  C   1 
ATOM   2288 O O   . VAL J 1 12 ? 124.780 106.671 106.127 1.00 54.65  ? 12 VAL D  O   1 
ATOM   2289 C CB  . VAL J 1 12 ? 124.755 104.497 103.991 1.00 38.02  ? 12 VAL D  CB  1 
ATOM   2290 C CG1 . VAL J 1 12 ? 123.358 104.576 103.421 1.00 36.81  ? 12 VAL D  CG1 1 
ATOM   2291 C CG2 . VAL J 1 12 ? 125.592 103.488 103.232 1.00 37.82  ? 12 VAL D  CG2 1 
ATOM   2292 N N   . HIS J 1 13 ? 124.087 107.868 104.349 1.00 39.40  ? 13 HIS D  N   1 
ATOM   2293 C CA  . HIS J 1 13 ? 123.376 108.818 105.191 1.00 42.52  ? 13 HIS D  CA  1 
ATOM   2294 C C   . HIS J 1 13 ? 122.230 109.456 104.424 1.00 39.69  ? 13 HIS D  C   1 
ATOM   2295 O O   . HIS J 1 13 ? 122.148 109.366 103.201 1.00 38.87  ? 13 HIS D  O   1 
ATOM   2296 C CB  . HIS J 1 13 ? 124.306 109.901 105.757 1.00 45.91  ? 13 HIS D  CB  1 
ATOM   2297 C CG  . HIS J 1 13 ? 125.277 110.464 104.768 1.00 46.41  ? 13 HIS D  CG  1 
ATOM   2298 N ND1 . HIS J 1 13 ? 125.259 111.787 104.384 1.00 43.92  ? 13 HIS D  ND1 1 
ATOM   2299 C CD2 . HIS J 1 13 ? 126.317 109.896 104.114 1.00 49.27  ? 13 HIS D  CD2 1 
ATOM   2300 C CE1 . HIS J 1 13 ? 126.233 112.005 103.520 1.00 48.42  ? 13 HIS D  CE1 1 
ATOM   2301 N NE2 . HIS J 1 13 ? 126.890 110.874 103.338 1.00 50.84  ? 13 HIS D  NE2 1 
ATOM   2302 N N   . HIS J 1 14 ? 121.324 110.078 105.178 1.00 39.43  ? 14 HIS D  N   1 
ATOM   2303 C CA  . HIS J 1 14 ? 120.207 110.851 104.636 1.00 36.41  ? 14 HIS D  CA  1 
ATOM   2304 C C   . HIS J 1 14 ? 119.329 110.005 103.713 1.00 34.91  ? 14 HIS D  C   1 
ATOM   2305 O O   . HIS J 1 14 ? 119.205 110.262 102.519 1.00 41.49  ? 14 HIS D  O   1 
ATOM   2306 C CB  . HIS J 1 14 ? 120.712 112.108 103.927 1.00 37.87  ? 14 HIS D  CB  1 
ATOM   2307 C CG  . HIS J 1 14 ? 121.330 113.106 104.852 1.00 43.65  ? 14 HIS D  CG  1 
ATOM   2308 N ND1 . HIS J 1 14 ? 122.675 113.112 105.148 1.00 45.90  ? 14 HIS D  ND1 1 
ATOM   2309 C CD2 . HIS J 1 14 ? 120.782 114.117 105.566 1.00 47.98  ? 14 HIS D  CD2 1 
ATOM   2310 C CE1 . HIS J 1 14 ? 122.932 114.092 105.995 1.00 53.85  ? 14 HIS D  CE1 1 
ATOM   2311 N NE2 . HIS J 1 14 ? 121.800 114.716 106.265 1.00 57.15  ? 14 HIS D  NE2 1 
ATOM   2312 N N   . GLN J 1 15 ? 118.704 108.988 104.296 1.00 31.09  ? 15 GLN D  N   1 
ATOM   2313 C CA  . GLN J 1 15 ? 117.788 108.116 103.576 1.00 25.82  ? 15 GLN D  CA  1 
ATOM   2314 C C   . GLN J 1 15 ? 116.398 108.237 104.176 1.00 27.11  ? 15 GLN D  C   1 
ATOM   2315 O O   . GLN J 1 15 ? 116.236 108.161 105.396 1.00 36.68  ? 15 GLN D  O   1 
ATOM   2316 C CB  . GLN J 1 15 ? 118.255 106.664 103.628 1.00 26.86  ? 15 GLN D  CB  1 
ATOM   2317 C CG  . GLN J 1 15 ? 119.036 106.234 102.413 1.00 36.02  ? 15 GLN D  CG  1 
ATOM   2318 C CD  . GLN J 1 15 ? 120.513 106.466 102.578 1.00 36.75  ? 15 GLN D  CD  1 
ATOM   2319 O OE1 . GLN J 1 15 ? 120.991 106.711 103.682 1.00 32.60  ? 15 GLN D  OE1 1 
ATOM   2320 N NE2 . GLN J 1 15 ? 121.250 106.398 101.478 1.00 36.88  ? 15 GLN D  NE2 1 
ATOM   2321 N N   . LYS J 1 16 ? 115.401 108.428 103.320 1.00 25.46  ? 16 LYS D  N   1 
ATOM   2322 C CA  . LYS J 1 16 ? 113.997 108.420 103.719 1.00 23.75  ? 16 LYS D  CA  1 
ATOM   2323 C C   . LYS J 1 16 ? 113.348 107.225 103.037 1.00 27.50  ? 16 LYS D  C   1 
ATOM   2324 O O   . LYS J 1 16 ? 113.021 107.282 101.849 1.00 37.91  ? 16 LYS D  O   1 
ATOM   2325 C CB  . LYS J 1 16 ? 113.304 109.722 103.344 1.00 23.54  ? 16 LYS D  CB  1 
ATOM   2326 C CG  . LYS J 1 16 ? 113.961 110.950 103.919 1.00 20.89  ? 16 LYS D  CG  1 
ATOM   2327 C CD  . LYS J 1 16 ? 113.125 112.176 103.654 1.00 22.06  ? 16 LYS D  CD  1 
ATOM   2328 C CE  . LYS J 1 16 ? 113.746 113.400 104.282 1.00 22.83  ? 16 LYS D  CE  1 
ATOM   2329 N NZ  . LYS J 1 16 ? 112.782 114.523 104.308 1.00 28.31  ? 16 LYS D  NZ  1 
ATOM   2330 N N   . LEU J 1 17 ? 113.160 106.145 103.786 1.00 23.96  ? 17 LEU D  N   1 
ATOM   2331 C CA  . LEU J 1 17 ? 112.679 104.885 103.241 1.00 25.08  ? 17 LEU D  CA  1 
ATOM   2332 C C   . LEU J 1 17 ? 111.312 104.564 103.820 1.00 25.06  ? 17 LEU D  C   1 
ATOM   2333 O O   . LEU J 1 17 ? 111.120 104.627 105.037 1.00 32.20  ? 17 LEU D  O   1 
ATOM   2334 C CB  . LEU J 1 17 ? 113.662 103.754 103.545 1.00 25.85  ? 17 LEU D  CB  1 
ATOM   2335 C CG  . LEU J 1 17 ? 113.503 102.468 102.739 1.00 28.96  ? 17 LEU D  CG  1 
ATOM   2336 C CD1 . LEU J 1 17 ? 114.860 101.970 102.297 1.00 37.70  ? 17 LEU D  CD1 1 
ATOM   2337 C CD2 . LEU J 1 17 ? 112.783 101.408 103.550 1.00 27.85  ? 17 LEU D  CD2 1 
ATOM   2338 N N   . VAL J 1 18 ? 110.367 104.227 102.949 1.00 24.89  ? 18 VAL D  N   1 
ATOM   2339 C CA  . VAL J 1 18 ? 109.059 103.725 103.350 1.00 26.58  ? 18 VAL D  CA  1 
ATOM   2340 C C   . VAL J 1 18 ? 108.875 102.354 102.723 1.00 29.85  ? 18 VAL D  C   1 
ATOM   2341 O O   . VAL J 1 18 ? 109.027 102.197 101.507 1.00 35.03  ? 18 VAL D  O   1 
ATOM   2342 C CB  . VAL J 1 18 ? 107.923 104.675 102.936 1.00 25.75  ? 18 VAL D  CB  1 
ATOM   2343 C CG1 . VAL J 1 18 ? 106.646 104.292 103.644 1.00 24.22  ? 18 VAL D  CG1 1 
ATOM   2344 C CG2 . VAL J 1 18 ? 108.290 106.107 103.256 1.00 24.63  ? 18 VAL D  CG2 1 
ATOM   2345 N N   . PHE J 1 19 ? 108.552 101.365 103.550 1.00 30.43  ? 19 PHE D  N   1 
ATOM   2346 C CA  . PHE J 1 19 ? 108.461 99.976  103.125 1.00 32.79  ? 19 PHE D  CA  1 
ATOM   2347 C C   . PHE J 1 19 ? 107.072 99.449  103.447 1.00 36.31  ? 19 PHE D  C   1 
ATOM   2348 O O   . PHE J 1 19 ? 106.691 99.378  104.619 1.00 43.04  ? 19 PHE D  O   1 
ATOM   2349 C CB  . PHE J 1 19 ? 109.534 99.133  103.817 1.00 36.08  ? 19 PHE D  CB  1 
ATOM   2350 C CG  . PHE J 1 19 ? 109.794 97.813  103.157 1.00 38.70  ? 19 PHE D  CG  1 
ATOM   2351 C CD1 . PHE J 1 19 ? 108.903 96.765  103.297 1.00 38.82  ? 19 PHE D  CD1 1 
ATOM   2352 C CD2 . PHE J 1 19 ? 110.938 97.615  102.411 1.00 41.78  ? 19 PHE D  CD2 1 
ATOM   2353 C CE1 . PHE J 1 19 ? 109.143 95.550  102.696 1.00 39.93  ? 19 PHE D  CE1 1 
ATOM   2354 C CE2 . PHE J 1 19 ? 111.183 96.401  101.808 1.00 44.10  ? 19 PHE D  CE2 1 
ATOM   2355 C CZ  . PHE J 1 19 ? 110.285 95.368  101.952 1.00 44.51  ? 19 PHE D  CZ  1 
ATOM   2356 N N   . PHE J 1 20 ? 106.325 99.080  102.414 1.00 35.86  ? 20 PHE D  N   1 
ATOM   2357 C CA  . PHE J 1 20 ? 105.022 98.449  102.565 1.00 37.59  ? 20 PHE D  CA  1 
ATOM   2358 C C   . PHE J 1 20 ? 105.146 96.976  102.211 1.00 45.25  ? 20 PHE D  C   1 
ATOM   2359 O O   . PHE J 1 20 ? 105.719 96.631  101.173 1.00 55.23  ? 20 PHE D  O   1 
ATOM   2360 C CB  . PHE J 1 20 ? 103.973 99.105  101.667 1.00 39.09  ? 20 PHE D  CB  1 
ATOM   2361 C CG  . PHE J 1 20 ? 103.631 100.511 102.051 1.00 38.58  ? 20 PHE D  CG  1 
ATOM   2362 C CD1 . PHE J 1 20 ? 104.333 101.575 101.523 1.00 36.65  ? 20 PHE D  CD1 1 
ATOM   2363 C CD2 . PHE J 1 20 ? 102.591 100.770 102.922 1.00 35.18  ? 20 PHE D  CD2 1 
ATOM   2364 C CE1 . PHE J 1 20 ? 104.013 102.868 101.865 1.00 33.87  ? 20 PHE D  CE1 1 
ATOM   2365 C CE2 . PHE J 1 20 ? 102.267 102.062 103.266 1.00 34.77  ? 20 PHE D  CE2 1 
ATOM   2366 C CZ  . PHE J 1 20 ? 102.979 103.112 102.738 1.00 31.87  ? 20 PHE D  CZ  1 
ATOM   2367 N N   . ALA J 1 21 ? 104.618 96.113  103.070 1.00 46.71  ? 21 ALA D  N   1 
ATOM   2368 C CA  . ALA J 1 21 ? 104.599 94.682  102.819 1.00 51.62  ? 21 ALA D  CA  1 
ATOM   2369 C C   . ALA J 1 21 ? 103.209 94.142  103.105 1.00 59.08  ? 21 ALA D  C   1 
ATOM   2370 O O   . ALA J 1 21 ? 102.578 94.523  104.094 1.00 64.50  ? 21 ALA D  O   1 
ATOM   2371 C CB  . ALA J 1 21 ? 105.637 93.949  103.673 1.00 47.68  ? 21 ALA D  CB  1 
ATOM   2372 N N   . GLU J 1 22 ? 102.731 93.263  102.234 1.00 62.23  ? 22 GLU D  N   1 
ATOM   2373 C CA  . GLU J 1 22 ? 101.424 92.649  102.416 1.00 69.45  ? 22 GLU D  CA  1 
ATOM   2374 C C   . GLU J 1 22 ? 101.502 91.146  102.213 1.00 74.34  ? 22 GLU D  C   1 
ATOM   2375 O O   . GLU J 1 22 ? 102.312 90.658  101.429 1.00 78.12  ? 22 GLU D  O   1 
ATOM   2376 C CB  . GLU J 1 22 ? 100.403 93.256  101.458 1.00 72.05  ? 22 GLU D  CB  1 
ATOM   2377 C CG  . GLU J 1 22 ? 99.823  94.568  101.935 1.00 71.84  ? 22 GLU D  CG  1 
ATOM   2378 C CD  . GLU J 1 22 ? 98.378  94.439  102.365 1.00 75.14  ? 22 GLU D  CD  1 
ATOM   2379 O OE1 . GLU J 1 22 ? 97.893  93.295  102.483 1.00 75.71  ? 22 GLU D  OE1 1 
ATOM   2380 O OE2 . GLU J 1 22 ? 97.725  95.482  102.585 1.00 74.25  ? 22 GLU D  OE2 1 
HETATM 2381 N N   . DAS J 1 23 ? 100.650 90.416  102.923 1.00 72.71  ? 23 DAS D  N   1 
HETATM 2382 C CA  . DAS J 1 23 ? 100.655 88.965  102.854 1.00 76.75  ? 23 DAS D  CA  1 
HETATM 2383 C C   . DAS J 1 23 ? 101.907 88.431  103.536 1.00 76.02  ? 23 DAS D  C   1 
HETATM 2384 O O   . DAS J 1 23 ? 101.925 88.246  104.752 1.00 76.84  ? 23 DAS D  O   1 
HETATM 2385 C CB  . DAS J 1 23 ? 99.404  88.398  103.524 1.00 83.90  ? 23 DAS D  CB  1 
HETATM 2386 C CG  . DAS J 1 23 ? 99.223  86.915  103.268 1.00 88.14  ? 23 DAS D  CG  1 
HETATM 2387 O OD1 . DAS J 1 23 ? 99.982  86.352  102.452 1.00 87.21  ? 23 DAS D  OD1 1 
HETATM 2388 O OD2 . DAS J 1 23 ? 98.319  86.312  103.883 1.00 86.54  ? 23 DAS D  OD2 1 
ATOM   2389 N N   . VAL J 1 24 ? 102.949 88.201  102.742 1.00 73.27  ? 24 VAL D  N   1 
ATOM   2390 C CA  . VAL J 1 24 ? 104.228 87.689  103.229 1.00 69.90  ? 24 VAL D  CA  1 
ATOM   2391 C C   . VAL J 1 24 ? 104.032 86.437  104.078 1.00 67.77  ? 24 VAL D  C   1 
ATOM   2392 O O   . VAL J 1 24 ? 104.230 86.459  105.289 1.00 70.39  ? 24 VAL D  O   1 
ATOM   2393 C CB  . VAL J 1 24 ? 104.995 88.765  104.016 1.00 64.79  ? 24 VAL D  CB  1 
ATOM   2394 C CG1 . VAL J 1 24 ? 106.435 88.342  104.218 1.00 56.42  ? 24 VAL D  CG1 1 
ATOM   2395 C CG2 . VAL J 1 24 ? 104.935 90.095  103.290 1.00 58.59  ? 24 VAL D  CG2 1 
ATOM   2396 N N   . GLY J 1 25 ? 103.637 85.341  103.436 1.00 65.16  ? 25 GLY D  N   1 
ATOM   2397 C CA  . GLY J 1 25 ? 103.369 84.096  104.131 1.00 63.72  ? 25 GLY D  CA  1 
ATOM   2398 C C   . GLY J 1 25 ? 104.529 83.128  103.992 1.00 65.69  ? 25 GLY D  C   1 
ATOM   2399 O O   . GLY J 1 25 ? 105.081 82.953  102.903 1.00 67.63  ? 25 GLY D  O   1 
ATOM   2400 N N   . SER J 1 26 ? 104.889 82.503  105.113 1.00 66.41  ? 26 SER D  N   1 
ATOM   2401 C CA  . SER J 1 26 ? 105.918 81.465  105.153 1.00 66.74  ? 26 SER D  CA  1 
ATOM   2402 C C   . SER J 1 26 ? 107.239 81.961  104.568 1.00 62.57  ? 26 SER D  C   1 
ATOM   2403 O O   . SER J 1 26 ? 107.896 81.277  103.782 1.00 59.58  ? 26 SER D  O   1 
ATOM   2404 C CB  . SER J 1 26 ? 105.442 80.200  104.436 1.00 65.12  ? 26 SER D  CB  1 
ATOM   2405 O OG  . SER J 1 26 ? 104.052 80.002  104.625 1.00 62.29  ? 26 SER D  OG  1 
ATOM   2406 N N   . ASN J 1 27 ? 107.628 83.170  104.961 1.00 58.74  ? 27 ASN D  N   1 
ATOM   2407 C CA  . ASN J 1 27 ? 108.893 83.732  104.510 1.00 53.96  ? 27 ASN D  CA  1 
ATOM   2408 C C   . ASN J 1 27 ? 110.050 83.006  105.183 1.00 54.07  ? 27 ASN D  C   1 
ATOM   2409 O O   . ASN J 1 27 ? 110.147 82.985  106.413 1.00 61.28  ? 27 ASN D  O   1 
ATOM   2410 C CB  . ASN J 1 27 ? 108.949 85.226  104.816 1.00 53.66  ? 27 ASN D  CB  1 
ATOM   2411 C CG  . ASN J 1 27 ? 110.367 85.758  104.858 1.00 48.69  ? 27 ASN D  CG  1 
ATOM   2412 O OD1 . ASN J 1 27 ? 111.108 85.656  103.884 1.00 46.96  ? 27 ASN D  OD1 1 
ATOM   2413 N ND2 . ASN J 1 27 ? 110.750 86.328  105.991 1.00 48.76  ? 27 ASN D  ND2 1 
ATOM   2414 N N   . LYS J 1 28 ? 110.923 82.407  104.378 1.00 49.39  ? 28 LYS D  N   1 
ATOM   2415 C CA  . LYS J 1 28 ? 112.117 81.744  104.880 1.00 50.70  ? 28 LYS D  CA  1 
ATOM   2416 C C   . LYS J 1 28 ? 113.391 82.514  104.571 1.00 50.43  ? 28 LYS D  C   1 
ATOM   2417 O O   . LYS J 1 28 ? 114.479 82.055  104.933 1.00 47.12  ? 28 LYS D  O   1 
ATOM   2418 C CB  . LYS J 1 28 ? 112.217 80.327  104.306 1.00 51.94  ? 28 LYS D  CB  1 
ATOM   2419 C CG  . LYS J 1 28 ? 110.967 79.495  104.512 1.00 54.88  ? 28 LYS D  CG  1 
ATOM   2420 C CD  . LYS J 1 28 ? 111.290 78.012  104.527 1.00 56.29  ? 28 LYS D  CD  1 
ATOM   2421 C CE  . LYS J 1 28 ? 110.024 77.175  104.581 1.00 61.55  ? 28 LYS D  CE  1 
ATOM   2422 N NZ  . LYS J 1 28 ? 108.798 78.019  104.577 1.00 55.99  ? 28 LYS D  NZ  1 
ATOM   2423 N N   . GLY J 1 29 ? 113.288 83.668  103.912 1.00 54.52  ? 29 GLY D  N   1 
ATOM   2424 C CA  . GLY J 1 29 ? 114.422 84.487  103.589 1.00 50.66  ? 29 GLY D  CA  1 
ATOM   2425 C C   . GLY J 1 29 ? 114.465 85.766  104.399 1.00 49.00  ? 29 GLY D  C   1 
ATOM   2426 O O   . GLY J 1 29 ? 113.802 85.906  105.435 1.00 48.69  ? 29 GLY D  O   1 
ATOM   2427 N N   . ALA J 1 30 ? 115.252 86.719  103.914 1.00 48.30  ? 30 ALA D  N   1 
ATOM   2428 C CA  . ALA J 1 30 ? 115.443 88.000  104.578 1.00 41.05  ? 30 ALA D  CA  1 
ATOM   2429 C C   . ALA J 1 30 ? 114.656 89.072  103.838 1.00 40.65  ? 30 ALA D  C   1 
ATOM   2430 O O   . ALA J 1 30 ? 114.831 89.250  102.629 1.00 43.98  ? 30 ALA D  O   1 
ATOM   2431 C CB  . ALA J 1 30 ? 116.924 88.369  104.638 1.00 35.72  ? 30 ALA D  CB  1 
ATOM   2432 N N   . ILE J 1 31 ? 113.797 89.780  104.561 1.00 38.51  ? 31 ILE D  N   1 
ATOM   2433 C CA  . ILE J 1 31 ? 113.060 90.921  104.033 1.00 37.05  ? 31 ILE D  CA  1 
ATOM   2434 C C   . ILE J 1 31 ? 113.542 92.149  104.788 1.00 40.18  ? 31 ILE D  C   1 
ATOM   2435 O O   . ILE J 1 31 ? 113.200 92.341  105.961 1.00 49.66  ? 31 ILE D  O   1 
ATOM   2436 C CB  . ILE J 1 31 ? 111.545 90.739  104.171 1.00 33.50  ? 31 ILE D  CB  1 
ATOM   2437 C CG1 . ILE J 1 31 ? 111.097 89.500  103.401 1.00 38.10  ? 31 ILE D  CG1 1 
ATOM   2438 C CG2 . ILE J 1 31 ? 110.815 91.976  103.682 1.00 30.82  ? 31 ILE D  CG2 1 
ATOM   2439 C CD1 . ILE J 1 31 ? 109.619 89.427  103.183 1.00 42.08  ? 31 ILE D  CD1 1 
ATOM   2440 N N   . ILE J 1 32 ? 114.334 92.983  104.124 1.00 37.80  ? 32 ILE D  N   1 
ATOM   2441 C CA  . ILE J 1 32 ? 115.005 94.108  104.759 1.00 42.84  ? 32 ILE D  CA  1 
ATOM   2442 C C   . ILE J 1 32 ? 114.600 95.391  104.053 1.00 42.30  ? 32 ILE D  C   1 
ATOM   2443 O O   . ILE J 1 32 ? 114.522 95.434  102.822 1.00 45.16  ? 32 ILE D  O   1 
ATOM   2444 C CB  . ILE J 1 32 ? 116.537 93.935  104.744 1.00 44.85  ? 32 ILE D  CB  1 
ATOM   2445 C CG1 . ILE J 1 32 ? 116.920 92.544  105.246 1.00 42.64  ? 32 ILE D  CG1 1 
ATOM   2446 C CG2 . ILE J 1 32 ? 117.197 94.994  105.600 1.00 48.55  ? 32 ILE D  CG2 1 
ATOM   2447 C CD1 . ILE J 1 32 ? 118.055 91.911  104.482 1.00 40.67  ? 32 ILE D  CD1 1 
ATOM   2448 N N   . GLY J 1 33 ? 114.328 96.431  104.833 1.00 44.70  ? 33 GLY D  N   1 
ATOM   2449 C CA  . GLY J 1 33 ? 114.038 97.732  104.269 1.00 40.70  ? 33 GLY D  CA  1 
ATOM   2450 C C   . GLY J 1 33 ? 115.286 98.411  103.750 1.00 40.23  ? 33 GLY D  C   1 
ATOM   2451 O O   . GLY J 1 33 ? 115.389 98.713  102.560 1.00 43.73  ? 33 GLY D  O   1 
ATOM   2452 N N   . LEU J 1 34 ? 116.244 98.661  104.638 1.00 41.37  ? 34 LEU D  N   1 
ATOM   2453 C CA  . LEU J 1 34 ? 117.540 99.212  104.267 1.00 41.56  ? 34 LEU D  CA  1 
ATOM   2454 C C   . LEU J 1 34 ? 118.615 98.307  104.841 1.00 43.59  ? 34 LEU D  C   1 
ATOM   2455 O O   . LEU J 1 34 ? 118.651 98.078  106.053 1.00 52.62  ? 34 LEU D  O   1 
ATOM   2456 C CB  . LEU J 1 34 ? 117.709 100.641 104.787 1.00 42.98  ? 34 LEU D  CB  1 
ATOM   2457 C CG  . LEU J 1 34 ? 118.842 101.463 104.172 1.00 39.98  ? 34 LEU D  CG  1 
ATOM   2458 C CD1 . LEU J 1 34 ? 118.337 102.841 103.788 1.00 33.09  ? 34 LEU D  CD1 1 
ATOM   2459 C CD2 . LEU J 1 34 ? 120.026 101.566 105.113 1.00 40.03  ? 34 LEU D  CD2 1 
ATOM   2460 N N   . MET J 1 35 ? 119.487 97.795  103.980 1.00 38.84  ? 35 MET D  N   1 
ATOM   2461 C CA  . MET J 1 35 ? 120.545 96.885  104.391 1.00 44.10  ? 35 MET D  CA  1 
ATOM   2462 C C   . MET J 1 35 ? 121.887 97.439  103.940 1.00 48.26  ? 35 MET D  C   1 
ATOM   2463 O O   . MET J 1 35 ? 122.056 97.784  102.768 1.00 57.64  ? 35 MET D  O   1 
ATOM   2464 C CB  . MET J 1 35 ? 120.326 95.491  103.806 1.00 46.59  ? 35 MET D  CB  1 
ATOM   2465 C CG  . MET J 1 35 ? 121.569 94.630  103.800 1.00 51.67  ? 35 MET D  CG  1 
ATOM   2466 S SD  . MET J 1 35 ? 121.694 93.559  105.234 1.00 73.51  ? 35 MET D  SD  1 
ATOM   2467 C CE  . MET J 1 35 ? 123.410 93.069  105.141 1.00 71.03  ? 35 MET D  CE  1 
ATOM   2468 N N   . VAL J 1 36 ? 122.832 97.527  104.869 1.00 48.97  ? 36 VAL D  N   1 
ATOM   2469 C CA  . VAL J 1 36 ? 124.198 97.942  104.576 1.00 50.21  ? 36 VAL D  CA  1 
ATOM   2470 C C   . VAL J 1 36 ? 125.125 96.838  105.056 1.00 56.88  ? 36 VAL D  C   1 
ATOM   2471 O O   . VAL J 1 36 ? 125.052 96.422  106.219 1.00 64.00  ? 36 VAL D  O   1 
ATOM   2472 C CB  . VAL J 1 36 ? 124.549 99.281  105.241 1.00 46.62  ? 36 VAL D  CB  1 
ATOM   2473 C CG1 . VAL J 1 36 ? 125.998 99.638  104.969 1.00 48.09  ? 36 VAL D  CG1 1 
ATOM   2474 C CG2 . VAL J 1 36 ? 123.624 100.376 104.745 1.00 41.47  ? 36 VAL D  CG2 1 
ATOM   2475 N N   . GLY J 1 37 ? 125.993 96.364  104.169 1.00 56.15  ? 37 GLY D  N   1 
ATOM   2476 C CA  . GLY J 1 37 ? 126.881 95.274  104.510 1.00 61.50  ? 37 GLY D  CA  1 
ATOM   2477 C C   . GLY J 1 37 ? 126.947 94.208  103.439 1.00 74.49  ? 37 GLY D  C   1 
ATOM   2478 O O   . GLY J 1 37 ? 127.371 94.479  102.313 1.00 81.43  ? 37 GLY D  O   1 
ATOM   2479 N N   . GLY J 1 38 ? 126.543 92.993  103.774 1.00 77.39  ? 38 GLY D  N   1 
ATOM   2480 C CA  . GLY J 1 38 ? 126.575 91.901  102.817 1.00 82.98  ? 38 GLY D  CA  1 
ATOM   2481 C C   . GLY J 1 38 ? 125.499 90.886  103.117 1.00 87.96  ? 38 GLY D  C   1 
ATOM   2482 O O   . GLY J 1 38 ? 125.243 90.549  104.277 1.00 86.27  ? 38 GLY D  O   1 
ATOM   2483 N N   . VAL J 1 39 ? 124.869 90.389  102.057 1.00 90.26  ? 39 VAL D  N   1 
ATOM   2484 C CA  . VAL J 1 39 ? 123.820 89.384  102.154 1.00 94.48  ? 39 VAL D  CA  1 
ATOM   2485 C C   . VAL J 1 39 ? 124.283 88.138  101.415 1.00 97.76  ? 39 VAL D  C   1 
ATOM   2486 O O   . VAL J 1 39 ? 124.606 88.200  100.224 1.00 93.80  ? 39 VAL D  O   1 
ATOM   2487 C CB  . VAL J 1 39 ? 122.486 89.896  101.580 1.00 91.47  ? 39 VAL D  CB  1 
ATOM   2488 C CG1 . VAL J 1 39 ? 121.535 88.739  101.332 1.00 90.96  ? 39 VAL D  CG1 1 
ATOM   2489 C CG2 . VAL J 1 39 ? 121.861 90.906  102.522 1.00 86.64  ? 39 VAL D  CG2 1 
ATOM   2490 N N   . VAL J 1 40 ? 124.319 87.013  102.123 1.00 101.84 ? 40 VAL D  N   1 
ATOM   2491 C CA  . VAL J 1 40 ? 124.686 85.724  101.551 1.00 102.74 ? 40 VAL D  CA  1 
ATOM   2492 C C   . VAL J 1 40 ? 123.501 84.788  101.725 1.00 105.52 ? 40 VAL D  C   1 
ATOM   2493 O O   . VAL J 1 40 ? 123.029 84.578  102.849 1.00 105.13 ? 40 VAL D  O   1 
ATOM   2494 C CB  . VAL J 1 40 ? 125.947 85.142  102.208 1.00 100.19 ? 40 VAL D  CB  1 
ATOM   2495 C CG1 . VAL J 1 40 ? 126.329 83.831  101.545 1.00 98.42  ? 40 VAL D  CG1 1 
ATOM   2496 C CG2 . VAL J 1 40 ? 127.091 86.137  102.130 1.00 97.85  ? 40 VAL D  CG2 1 
ATOM   2497 N N   . ILE J 1 41 ? 123.023 84.227  100.619 1.00 108.51 ? 41 ILE D  N   1 
ATOM   2498 C CA  . ILE J 1 41 ? 121.873 83.331  100.622 1.00 112.67 ? 41 ILE D  CA  1 
ATOM   2499 C C   . ILE J 1 41 ? 122.349 81.929  100.276 1.00 116.23 ? 41 ILE D  C   1 
ATOM   2500 O O   . ILE J 1 41 ? 123.023 81.726  99.258  1.00 115.97 ? 41 ILE D  O   1 
ATOM   2501 C CB  . ILE J 1 41 ? 120.796 83.806  99.633  1.00 112.79 ? 41 ILE D  CB  1 
ATOM   2502 C CG1 . ILE J 1 41 ? 120.474 85.282  99.867  1.00 107.76 ? 41 ILE D  CG1 1 
ATOM   2503 C CG2 . ILE J 1 41 ? 119.541 82.961  99.769  1.00 110.95 ? 41 ILE D  CG2 1 
ATOM   2504 C CD1 . ILE J 1 41 ? 119.547 85.868  98.832  1.00 104.16 ? 41 ILE D  CD1 1 
ATOM   2505 N N   . ALA J 1 42 ? 122.001 80.964  101.119 1.00 118.92 ? 42 ALA D  N   1 
ATOM   2506 C CA  . ALA J 1 42 ? 122.398 79.579  100.902 1.00 121.66 ? 42 ALA D  CA  1 
ATOM   2507 C C   . ALA J 1 42 ? 121.305 78.623  101.367 1.00 127.02 ? 42 ALA D  C   1 
ATOM   2508 O O   . ALA J 1 42 ? 120.379 79.016  102.077 1.00 129.60 ? 42 ALA D  O   1 
ATOM   2509 C CB  . ALA J 1 42 ? 123.704 79.284  101.621 1.00 117.58 ? 42 ALA D  CB  1 
ATOM   2510 O OXT . ALA J 1 42 ? 121.319 77.436  101.042 1.00 127.70 ? 42 ALA D  OXT 1 
ATOM   2511 N N   . GLY K 1 9  ? 135.588 102.915 98.244  1.00 75.58  ? 9  GLY E  N   1 
ATOM   2512 C CA  . GLY K 1 9  ? 134.658 103.497 99.194  1.00 77.59  ? 9  GLY E  CA  1 
ATOM   2513 C C   . GLY K 1 9  ? 133.365 103.958 98.555  1.00 77.76  ? 9  GLY E  C   1 
ATOM   2514 O O   . GLY K 1 9  ? 133.376 104.593 97.502  1.00 78.65  ? 9  GLY E  O   1 
ATOM   2515 N N   . TYR K 1 10 ? 132.245 103.641 99.195  1.00 74.83  ? 10 TYR E  N   1 
ATOM   2516 C CA  . TYR K 1 10 ? 130.922 103.997 98.701  1.00 70.87  ? 10 TYR E  CA  1 
ATOM   2517 C C   . TYR K 1 10 ? 130.370 105.147 99.528  1.00 65.85  ? 10 TYR E  C   1 
ATOM   2518 O O   . TYR K 1 10 ? 130.435 105.117 100.761 1.00 68.66  ? 10 TYR E  O   1 
ATOM   2519 C CB  . TYR K 1 10 ? 129.965 102.804 98.763  1.00 71.13  ? 10 TYR E  CB  1 
ATOM   2520 C CG  . TYR K 1 10 ? 130.397 101.601 97.955  1.00 81.03  ? 10 TYR E  CG  1 
ATOM   2521 C CD1 . TYR K 1 10 ? 131.355 101.710 96.957  1.00 83.11  ? 10 TYR E  CD1 1 
ATOM   2522 C CD2 . TYR K 1 10 ? 129.833 100.354 98.185  1.00 80.21  ? 10 TYR E  CD2 1 
ATOM   2523 C CE1 . TYR K 1 10 ? 131.749 100.610 96.221  1.00 84.09  ? 10 TYR E  CE1 1 
ATOM   2524 C CE2 . TYR K 1 10 ? 130.219 99.250  97.453  1.00 87.12  ? 10 TYR E  CE2 1 
ATOM   2525 C CZ  . TYR K 1 10 ? 131.175 99.384  96.471  1.00 91.17  ? 10 TYR E  CZ  1 
ATOM   2526 O OH  . TYR K 1 10 ? 131.561 98.286  95.738  1.00 91.09  ? 10 TYR E  OH  1 
ATOM   2527 N N   . GLU K 1 11 ? 129.833 106.157 98.852  1.00 61.80  ? 11 GLU E  N   1 
ATOM   2528 C CA  . GLU K 1 11 ? 129.202 107.301 99.504  1.00 57.88  ? 11 GLU E  CA  1 
ATOM   2529 C C   . GLU K 1 11 ? 127.793 107.435 98.941  1.00 52.72  ? 11 GLU E  C   1 
ATOM   2530 O O   . GLU K 1 11 ? 127.598 108.011 97.868  1.00 58.89  ? 11 GLU E  O   1 
ATOM   2531 C CB  . GLU K 1 11 ? 130.010 108.575 99.294  1.00 61.88  ? 11 GLU E  CB  1 
ATOM   2532 C CG  . GLU K 1 11 ? 129.744 109.645 100.334 1.00 65.71  ? 11 GLU E  CG  1 
ATOM   2533 C CD  . GLU K 1 11 ? 130.363 110.977 99.970  1.00 76.41  ? 11 GLU E  CD  1 
ATOM   2534 O OE1 . GLU K 1 11 ? 131.581 111.014 99.698  1.00 81.59  ? 11 GLU E  OE1 1 
ATOM   2535 O OE2 . GLU K 1 11 ? 129.633 111.989 99.961  1.00 75.54  ? 11 GLU E  OE2 1 
ATOM   2536 N N   . VAL K 1 12 ? 126.815 106.905 99.666  1.00 47.56  ? 12 VAL E  N   1 
ATOM   2537 C CA  . VAL K 1 12 ? 125.417 106.915 99.254  1.00 41.82  ? 12 VAL E  CA  1 
ATOM   2538 C C   . VAL K 1 12 ? 124.666 107.846 100.191 1.00 43.59  ? 12 VAL E  C   1 
ATOM   2539 O O   . VAL K 1 12 ? 124.720 107.677 101.414 1.00 54.65  ? 12 VAL E  O   1 
ATOM   2540 C CB  . VAL K 1 12 ? 124.817 105.502 99.281  1.00 38.02  ? 12 VAL E  CB  1 
ATOM   2541 C CG1 . VAL K 1 12 ? 123.419 105.504 98.707  1.00 36.81  ? 12 VAL E  CG1 1 
ATOM   2542 C CG2 . VAL K 1 12 ? 125.708 104.538 98.525  1.00 37.82  ? 12 VAL E  CG2 1 
ATOM   2543 N N   . HIS K 1 13 ? 123.968 108.832 99.632  1.00 39.40  ? 13 HIS E  N   1 
ATOM   2544 C CA  . HIS K 1 13 ? 123.205 109.743 100.471 1.00 42.52  ? 13 HIS E  CA  1 
ATOM   2545 C C   . HIS K 1 13 ? 122.028 110.318 99.701  1.00 39.69  ? 13 HIS E  C   1 
ATOM   2546 O O   . HIS K 1 13 ? 121.953 110.222 98.478  1.00 38.87  ? 13 HIS E  O   1 
ATOM   2547 C CB  . HIS K 1 13 ? 124.074 110.876 101.038 1.00 45.91  ? 13 HIS E  CB  1 
ATOM   2548 C CG  . HIS K 1 13 ? 125.015 111.488 100.049 1.00 46.41  ? 13 HIS E  CG  1 
ATOM   2549 N ND1 . HIS K 1 13 ? 124.927 112.808 99.664  1.00 43.92  ? 13 HIS E  ND1 1 
ATOM   2550 C CD2 . HIS K 1 13 ? 126.086 110.977 99.398  1.00 49.27  ? 13 HIS E  CD2 1 
ATOM   2551 C CE1 . HIS K 1 13 ? 125.890 113.077 98.802  1.00 48.42  ? 13 HIS E  CE1 1 
ATOM   2552 N NE2 . HIS K 1 13 ? 126.607 111.983 98.623  1.00 50.84  ? 13 HIS E  NE2 1 
ATOM   2553 N N   . HIS K 1 14 ? 121.088 110.891 100.451 1.00 39.43  ? 14 HIS E  N   1 
ATOM   2554 C CA  . HIS K 1 14 ? 119.932 111.603 99.906  1.00 36.41  ? 14 HIS E  CA  1 
ATOM   2555 C C   . HIS K 1 14 ? 119.103 110.710 98.982  1.00 34.91  ? 14 HIS E  C   1 
ATOM   2556 O O   . HIS K 1 14 ? 118.969 110.958 97.788  1.00 41.49  ? 14 HIS E  O   1 
ATOM   2557 C CB  . HIS K 1 14 ? 120.370 112.884 99.196  1.00 37.87  ? 14 HIS E  CB  1 
ATOM   2558 C CG  . HIS K 1 14 ? 120.932 113.915 100.121 1.00 43.65  ? 14 HIS E  CG  1 
ATOM   2559 N ND1 . HIS K 1 14 ? 122.274 113.994 100.420 1.00 45.90  ? 14 HIS E  ND1 1 
ATOM   2560 C CD2 . HIS K 1 14 ? 120.329 114.896 100.832 1.00 47.98  ? 14 HIS E  CD2 1 
ATOM   2561 C CE1 . HIS K 1 14 ? 122.476 114.987 101.266 1.00 53.85  ? 14 HIS E  CE1 1 
ATOM   2562 N NE2 . HIS K 1 14 ? 121.312 115.550 101.533 1.00 57.15  ? 14 HIS E  NE2 1 
ATOM   2563 N N   . GLN K 1 15 ? 118.533 109.661 99.565  1.00 31.09  ? 15 GLN E  N   1 
ATOM   2564 C CA  . GLN K 1 15 ? 117.666 108.740 98.845  1.00 25.82  ? 15 GLN E  CA  1 
ATOM   2565 C C   . GLN K 1 15 ? 116.270 108.787 99.441  1.00 27.11  ? 15 GLN E  C   1 
ATOM   2566 O O   . GLN K 1 15 ? 116.110 108.704 100.661 1.00 36.68  ? 15 GLN E  O   1 
ATOM   2567 C CB  . GLN K 1 15 ? 118.210 107.315 98.899  1.00 26.86  ? 15 GLN E  CB  1 
ATOM   2568 C CG  . GLN K 1 15 ? 119.016 106.926 97.687  1.00 36.02  ? 15 GLN E  CG  1 
ATOM   2569 C CD  . GLN K 1 15 ? 120.479 107.238 97.855  1.00 36.75  ? 15 GLN E  CD  1 
ATOM   2570 O OE1 . GLN K 1 15 ? 120.940 107.509 98.959  1.00 32.60  ? 15 GLN E  OE1 1 
ATOM   2571 N NE2 . GLN K 1 15 ? 121.220 107.208 96.757  1.00 36.88  ? 15 GLN E  NE2 1 
ATOM   2572 N N   . LYS K 1 16 ? 115.267 108.923 98.583  1.00 25.46  ? 16 LYS E  N   1 
ATOM   2573 C CA  . LYS K 1 16 ? 113.864 108.840 98.979  1.00 23.75  ? 16 LYS E  CA  1 
ATOM   2574 C C   . LYS K 1 16 ? 113.282 107.610 98.298  1.00 27.50  ? 16 LYS E  C   1 
ATOM   2575 O O   . LYS K 1 16 ? 112.955 107.648 97.109  1.00 37.91  ? 16 LYS E  O   1 
ATOM   2576 C CB  . LYS K 1 16 ? 113.103 110.102 98.600  1.00 23.54  ? 16 LYS E  CB  1 
ATOM   2577 C CG  . LYS K 1 16 ? 113.691 111.364 99.175  1.00 20.89  ? 16 LYS E  CG  1 
ATOM   2578 C CD  . LYS K 1 16 ? 112.792 112.543 98.906  1.00 22.06  ? 16 LYS E  CD  1 
ATOM   2579 C CE  . LYS K 1 16 ? 113.345 113.800 99.533  1.00 22.83  ? 16 LYS E  CE  1 
ATOM   2580 N NZ  . LYS K 1 16 ? 112.321 114.870 99.555  1.00 28.31  ? 16 LYS E  NZ  1 
ATOM   2581 N N   . LEU K 1 17 ? 113.151 106.523 99.047  1.00 23.96  ? 17 LEU E  N   1 
ATOM   2582 C CA  . LEU K 1 17 ? 112.740 105.239 98.503  1.00 25.08  ? 17 LEU E  CA  1 
ATOM   2583 C C   . LEU K 1 17 ? 111.390 104.845 99.080  1.00 25.06  ? 17 LEU E  C   1 
ATOM   2584 O O   . LEU K 1 17 ? 111.192 104.899 100.296 1.00 32.20  ? 17 LEU E  O   1 
ATOM   2585 C CB  . LEU K 1 17 ? 113.781 104.163 98.811  1.00 25.85  ? 17 LEU E  CB  1 
ATOM   2586 C CG  . LEU K 1 17 ? 113.693 102.868 98.007  1.00 28.96  ? 17 LEU E  CG  1 
ATOM   2587 C CD1 . LEU K 1 17 ? 115.077 102.444 97.568  1.00 37.70  ? 17 LEU E  CD1 1 
ATOM   2588 C CD2 . LEU K 1 17 ? 113.030 101.772 98.817  1.00 27.85  ? 17 LEU E  CD2 1 
ATOM   2589 N N   . VAL K 1 18 ? 110.466 104.456 98.207  1.00 24.89  ? 18 VAL E  N   1 
ATOM   2590 C CA  . VAL K 1 18 ? 109.187 103.886 98.606  1.00 26.58  ? 18 VAL E  CA  1 
ATOM   2591 C C   . VAL K 1 18 ? 109.078 102.505 97.981  1.00 29.85  ? 18 VAL E  C   1 
ATOM   2592 O O   . VAL K 1 18 ? 109.241 102.355 96.765  1.00 35.03  ? 18 VAL E  O   1 
ATOM   2593 C CB  . VAL K 1 18 ? 108.002 104.773 98.188  1.00 25.75  ? 18 VAL E  CB  1 
ATOM   2594 C CG1 . VAL K 1 18 ? 106.746 104.322 98.893  1.00 24.22  ? 18 VAL E  CG1 1 
ATOM   2595 C CG2 . VAL K 1 18 ? 108.291 106.223 98.507  1.00 24.63  ? 18 VAL E  CG2 1 
ATOM   2596 N N   . PHE K 1 19 ? 108.807 101.502 98.808  1.00 30.43  ? 19 PHE E  N   1 
ATOM   2597 C CA  . PHE K 1 19 ? 108.792 100.109 98.385  1.00 32.79  ? 19 PHE E  CA  1 
ATOM   2598 C C   . PHE K 1 19 ? 107.433 99.509  98.705  1.00 36.31  ? 19 PHE E  C   1 
ATOM   2599 O O   . PHE K 1 19 ? 107.053 99.419  99.876  1.00 43.04  ? 19 PHE E  O   1 
ATOM   2600 C CB  . PHE K 1 19 ? 109.906 99.326  99.080  1.00 36.08  ? 19 PHE E  CB  1 
ATOM   2601 C CG  . PHE K 1 19 ? 110.239 98.021  98.424  1.00 38.70  ? 19 PHE E  CG  1 
ATOM   2602 C CD1 . PHE K 1 19 ? 109.406 96.927  98.563  1.00 38.82  ? 19 PHE E  CD1 1 
ATOM   2603 C CD2 . PHE K 1 19 ? 111.394 97.884  97.680  1.00 41.78  ? 19 PHE E  CD2 1 
ATOM   2604 C CE1 . PHE K 1 19 ? 109.712 95.726  97.964  1.00 39.93  ? 19 PHE E  CE1 1 
ATOM   2605 C CE2 . PHE K 1 19 ? 111.705 96.684  97.080  1.00 44.10  ? 19 PHE E  CE2 1 
ATOM   2606 C CZ  . PHE K 1 19 ? 110.864 95.605  97.223  1.00 44.51  ? 19 PHE E  CZ  1 
ATOM   2607 N N   . PHE K 1 20 ? 106.708 99.099  97.671  1.00 35.86  ? 20 PHE E  N   1 
ATOM   2608 C CA  . PHE K 1 20 ? 105.441 98.398  97.820  1.00 37.59  ? 20 PHE E  CA  1 
ATOM   2609 C C   . PHE K 1 20 ? 105.645 96.934  97.468  1.00 45.25  ? 20 PHE E  C   1 
ATOM   2610 O O   . PHE K 1 20 ? 106.238 96.619  96.432  1.00 55.23  ? 20 PHE E  O   1 
ATOM   2611 C CB  . PHE K 1 20 ? 104.360 98.996  96.919  1.00 39.09  ? 20 PHE E  CB  1 
ATOM   2612 C CG  . PHE K 1 20 ? 103.942 100.382 97.300  1.00 38.58  ? 20 PHE E  CG  1 
ATOM   2613 C CD1 . PHE K 1 20 ? 104.588 101.482 96.772  1.00 36.65  ? 20 PHE E  CD1 1 
ATOM   2614 C CD2 . PHE K 1 20 ? 102.888 100.586 98.168  1.00 35.18  ? 20 PHE E  CD2 1 
ATOM   2615 C CE1 . PHE K 1 20 ? 104.197 102.756 97.111  1.00 33.87  ? 20 PHE E  CE1 1 
ATOM   2616 C CE2 . PHE K 1 20 ? 102.494 101.860 98.510  1.00 34.77  ? 20 PHE E  CE2 1 
ATOM   2617 C CZ  . PHE K 1 20 ? 103.150 102.945 97.981  1.00 31.87  ? 20 PHE E  CZ  1 
ATOM   2618 N N   . ALA K 1 21 ? 105.162 96.045  98.327  1.00 46.71  ? 21 ALA E  N   1 
ATOM   2619 C CA  . ALA K 1 21 ? 105.221 94.614  98.079  1.00 51.62  ? 21 ALA E  CA  1 
ATOM   2620 C C   . ALA K 1 21 ? 103.861 94.001  98.363  1.00 59.08  ? 21 ALA E  C   1 
ATOM   2621 O O   . ALA K 1 21 ? 103.208 94.349  99.349  1.00 64.50  ? 21 ALA E  O   1 
ATOM   2622 C CB  . ALA K 1 21 ? 106.295 93.940  98.936  1.00 47.68  ? 21 ALA E  CB  1 
ATOM   2623 N N   . GLU K 1 22 ? 103.433 93.097  97.491  1.00 62.23  ? 22 GLU E  N   1 
ATOM   2624 C CA  . GLU K 1 22 ? 102.161 92.414  97.672  1.00 69.45  ? 22 GLU E  CA  1 
ATOM   2625 C C   . GLU K 1 22 ? 102.320 90.916  97.471  1.00 74.34  ? 22 GLU E  C   1 
ATOM   2626 O O   . GLU K 1 22 ? 103.157 90.472  96.690  1.00 78.12  ? 22 GLU E  O   1 
ATOM   2627 C CB  . GLU K 1 22 ? 101.111 92.963  96.711  1.00 72.05  ? 22 GLU E  CB  1 
ATOM   2628 C CG  . GLU K 1 22 ? 100.460 94.243  97.184  1.00 71.84  ? 22 GLU E  CG  1 
ATOM   2629 C CD  . GLU K 1 22 ? 99.023  94.037  97.611  1.00 75.14  ? 22 GLU E  CD  1 
ATOM   2630 O OE1 . GLU K 1 22 ? 98.600  92.868  97.730  1.00 75.71  ? 22 GLU E  OE1 1 
ATOM   2631 O OE2 . GLU K 1 22 ? 98.314  95.043  97.828  1.00 74.25  ? 22 GLU E  OE2 1 
HETATM 2632 N N   . DAS K 1 23 ? 101.507 90.143  98.180  1.00 72.71  ? 23 DAS E  N   1 
HETATM 2633 C CA  . DAS K 1 23 ? 101.590 88.694  98.113  1.00 76.75  ? 23 DAS E  CA  1 
HETATM 2634 C C   . DAS K 1 23 ? 102.867 88.229  98.800  1.00 76.02  ? 23 DAS E  C   1 
HETATM 2635 O O   . DAS K 1 23 ? 102.892 88.047  100.015 1.00 76.84  ? 23 DAS E  O   1 
HETATM 2636 C CB  . DAS K 1 23 ? 100.369 88.062  98.782  1.00 83.90  ? 23 DAS E  CB  1 
HETATM 2637 C CG  . DAS K 1 23 ? 100.269 86.571  98.527  1.00 88.14  ? 23 DAS E  CG  1 
HETATM 2638 O OD1 . DAS K 1 23 ? 101.060 86.048  97.714  1.00 87.21  ? 23 DAS E  OD1 1 
HETATM 2639 O OD2 . DAS K 1 23 ? 99.398  85.920  99.142  1.00 86.54  ? 23 DAS E  OD2 1 
ATOM   2640 N N   . VAL K 1 24 ? 103.922 88.054  98.008  1.00 73.27  ? 24 VAL E  N   1 
ATOM   2641 C CA  . VAL K 1 24 ? 105.226 87.612  98.499  1.00 69.90  ? 24 VAL E  CA  1 
ATOM   2642 C C   . VAL K 1 24 ? 105.095 86.353  99.349  1.00 67.77  ? 24 VAL E  C   1 
ATOM   2643 O O   . VAL K 1 24 ? 105.289 86.387  100.561 1.00 70.39  ? 24 VAL E  O   1 
ATOM   2644 C CB  . VAL K 1 24 ? 105.931 88.730  99.285  1.00 64.79  ? 24 VAL E  CB  1 
ATOM   2645 C CG1 . VAL K 1 24 ? 107.392 88.385  99.492  1.00 56.42  ? 24 VAL E  CG1 1 
ATOM   2646 C CG2 . VAL K 1 24 ? 105.802 90.053  98.557  1.00 58.59  ? 24 VAL E  CG2 1 
ATOM   2647 N N   . GLY K 1 25 ? 104.761 85.236  98.707  1.00 65.16  ? 25 GLY E  N   1 
ATOM   2648 C CA  . GLY K 1 25 ? 104.559 83.980  99.404  1.00 63.72  ? 25 GLY E  CA  1 
ATOM   2649 C C   . GLY K 1 25 ? 105.770 83.076  99.269  1.00 65.69  ? 25 GLY E  C   1 
ATOM   2650 O O   . GLY K 1 25 ? 106.332 82.929  98.182  1.00 67.63  ? 25 GLY E  O   1 
ATOM   2651 N N   . SER K 1 26 ? 106.160 82.472  100.391 1.00 66.41  ? 26 SER E  N   1 
ATOM   2652 C CA  . SER K 1 26 ? 107.243 81.491  100.435 1.00 66.74  ? 26 SER E  CA  1 
ATOM   2653 C C   . SER K 1 26 ? 108.537 82.057  99.853  1.00 62.57  ? 26 SER E  C   1 
ATOM   2654 O O   . SER K 1 26 ? 109.231 81.408  99.069  1.00 59.58  ? 26 SER E  O   1 
ATOM   2655 C CB  . SER K 1 26 ? 106.838 80.201  99.720  1.00 65.12  ? 26 SER E  CB  1 
ATOM   2656 O OG  . SER K 1 26 ? 105.460 79.929  99.905  1.00 62.29  ? 26 SER E  OG  1 
ATOM   2657 N N   . ASN K 1 27 ? 108.859 83.285  100.245 1.00 58.74  ? 27 ASN E  N   1 
ATOM   2658 C CA  . ASN K 1 27 ? 110.094 83.914  99.796  1.00 53.96  ? 27 ASN E  CA  1 
ATOM   2659 C C   . ASN K 1 27 ? 111.286 83.253  100.472 1.00 54.07  ? 27 ASN E  C   1 
ATOM   2660 O O   . ASN K 1 27 ? 111.382 83.238  101.703 1.00 61.28  ? 27 ASN E  O   1 
ATOM   2661 C CB  . ASN K 1 27 ? 110.068 85.409  100.099 1.00 53.66  ? 27 ASN E  CB  1 
ATOM   2662 C CG  . ASN K 1 27 ? 111.455 86.017  100.144 1.00 48.69  ? 27 ASN E  CG  1 
ATOM   2663 O OD1 . ASN K 1 27 ? 112.204 85.954  99.172  1.00 46.96  ? 27 ASN E  OD1 1 
ATOM   2664 N ND2 . ASN K 1 27 ? 111.805 86.609  101.277 1.00 48.76  ? 27 ASN E  ND2 1 
ATOM   2665 N N   . LYS K 1 28 ? 112.193 82.700  99.670  1.00 49.39  ? 28 LYS E  N   1 
ATOM   2666 C CA  . LYS K 1 28 ? 113.419 82.103  100.176 1.00 50.70  ? 28 LYS E  CA  1 
ATOM   2667 C C   . LYS K 1 28 ? 114.651 82.940  99.869  1.00 50.43  ? 28 LYS E  C   1 
ATOM   2668 O O   . LYS K 1 28 ? 115.761 82.541  100.233 1.00 47.12  ? 28 LYS E  O   1 
ATOM   2669 C CB  . LYS K 1 28 ? 113.596 80.693  99.605  1.00 51.94  ? 28 LYS E  CB  1 
ATOM   2670 C CG  . LYS K 1 28 ? 112.393 79.794  99.809  1.00 54.88  ? 28 LYS E  CG  1 
ATOM   2671 C CD  . LYS K 1 28 ? 112.794 78.331  99.827  1.00 56.29  ? 28 LYS E  CD  1 
ATOM   2672 C CE  . LYS K 1 28 ? 111.576 77.427  99.879  1.00 61.55  ? 28 LYS E  CE  1 
ATOM   2673 N NZ  . LYS K 1 28 ? 110.306 78.204  99.871  1.00 55.99  ? 28 LYS E  NZ  1 
ATOM   2674 N N   . GLY K 1 29 ? 114.487 84.085  99.207  1.00 54.52  ? 29 GLY E  N   1 
ATOM   2675 C CA  . GLY K 1 29 ? 115.576 84.965  98.886  1.00 50.66  ? 29 GLY E  CA  1 
ATOM   2676 C C   . GLY K 1 29 ? 115.548 86.244  99.694  1.00 49.00  ? 29 GLY E  C   1 
ATOM   2677 O O   . GLY K 1 29 ? 114.876 86.350  100.728 1.00 48.69  ? 29 GLY E  O   1 
ATOM   2678 N N   . ALA K 1 30 ? 116.284 87.238  99.210  1.00 48.30  ? 30 ALA E  N   1 
ATOM   2679 C CA  . ALA K 1 30 ? 116.404 88.529  99.872  1.00 41.05  ? 30 ALA E  CA  1 
ATOM   2680 C C   . ALA K 1 30 ? 115.563 89.555  99.128  1.00 40.65  ? 30 ALA E  C   1 
ATOM   2681 O O   . ALA K 1 30 ? 115.731 89.741  97.920  1.00 43.98  ? 30 ALA E  O   1 
ATOM   2682 C CB  . ALA K 1 30 ? 117.863 88.976  99.935  1.00 35.72  ? 30 ALA E  CB  1 
ATOM   2683 N N   . ILE K 1 31 ? 114.665 90.217  99.849  1.00 38.51  ? 31 ILE E  N   1 
ATOM   2684 C CA  . ILE K 1 31 ? 113.869 91.316  99.317  1.00 37.05  ? 31 ILE E  CA  1 
ATOM   2685 C C   . ILE K 1 31 ? 114.282 92.569  100.072 1.00 40.18  ? 31 ILE E  C   1 
ATOM   2686 O O   . ILE K 1 31 ? 113.928 92.744  101.243 1.00 49.66  ? 31 ILE E  O   1 
ATOM   2687 C CB  . ILE K 1 31 ? 112.366 91.053  99.452  1.00 33.50  ? 31 ILE E  CB  1 
ATOM   2688 C CG1 . ILE K 1 31 ? 111.987 89.790  98.683  1.00 38.10  ? 31 ILE E  CG1 1 
ATOM   2689 C CG2 . ILE K 1 31 ? 111.571 92.248  98.960  1.00 30.82  ? 31 ILE E  CG2 1 
ATOM   2690 C CD1 . ILE K 1 31 ? 110.515 89.638  98.462  1.00 42.08  ? 31 ILE E  CD1 1 
ATOM   2691 N N   . ILE K 1 32 ? 115.030 93.443  99.407  1.00 37.80  ? 32 ILE E  N   1 
ATOM   2692 C CA  . ILE K 1 32 ? 115.638 94.604  100.043 1.00 42.84  ? 32 ILE E  CA  1 
ATOM   2693 C C   . ILE K 1 32 ? 115.166 95.863  99.333  1.00 42.30  ? 32 ILE E  C   1 
ATOM   2694 O O   . ILE K 1 32 ? 115.088 95.900  98.102  1.00 45.16  ? 32 ILE E  O   1 
ATOM   2695 C CB  . ILE K 1 32 ? 117.177 94.514  100.032 1.00 44.85  ? 32 ILE E  CB  1 
ATOM   2696 C CG1 . ILE K 1 32 ? 117.634 93.146  100.536 1.00 42.64  ? 32 ILE E  CG1 1 
ATOM   2697 C CG2 . ILE K 1 32 ? 117.777 95.608  100.887 1.00 48.55  ? 32 ILE E  CG2 1 
ATOM   2698 C CD1 . ILE K 1 32 ? 118.802 92.574  99.775  1.00 40.67  ? 32 ILE E  CD1 1 
ATOM   2699 N N   . GLY K 1 33 ? 114.837 96.887  100.112 1.00 44.70  ? 33 GLY E  N   1 
ATOM   2700 C CA  . GLY K 1 33 ? 114.478 98.170  99.545  1.00 40.70  ? 33 GLY E  CA  1 
ATOM   2701 C C   . GLY K 1 33 ? 115.690 98.915  99.028  1.00 40.23  ? 33 GLY E  C   1 
ATOM   2702 O O   . GLY K 1 33 ? 115.779 99.220  97.838  1.00 43.73  ? 33 GLY E  O   1 
ATOM   2703 N N   . LEU K 1 34 ? 116.630 99.217  99.918  1.00 41.37  ? 34 LEU E  N   1 
ATOM   2704 C CA  . LEU K 1 34 ? 117.896 99.837  99.548  1.00 41.56  ? 34 LEU E  CA  1 
ATOM   2705 C C   . LEU K 1 34 ? 119.017 98.991  100.126 1.00 43.59  ? 34 LEU E  C   1 
ATOM   2706 O O   . LEU K 1 34 ? 119.062 98.767  101.339 1.00 52.62  ? 34 LEU E  O   1 
ATOM   2707 C CB  . LEU K 1 34 ? 117.986 101.273 100.067 1.00 42.98  ? 34 LEU E  CB  1 
ATOM   2708 C CG  . LEU K 1 34 ? 119.075 102.154 99.453  1.00 39.98  ? 34 LEU E  CG  1 
ATOM   2709 C CD1 . LEU K 1 34 ? 118.498 103.502 99.066  1.00 33.09  ? 34 LEU E  CD1 1 
ATOM   2710 C CD2 . LEU K 1 34 ? 120.250 102.322 100.396 1.00 40.03  ? 34 LEU E  CD2 1 
ATOM   2711 N N   . MET K 1 35 ? 119.917 98.526  99.268  1.00 38.84  ? 35 MET E  N   1 
ATOM   2712 C CA  . MET K 1 35 ? 121.022 97.675  99.682  1.00 44.10  ? 35 MET E  CA  1 
ATOM   2713 C C   . MET K 1 35 ? 122.333 98.299  99.234  1.00 48.26  ? 35 MET E  C   1 
ATOM   2714 O O   . MET K 1 35 ? 122.486 98.651  98.062  1.00 57.64  ? 35 MET E  O   1 
ATOM   2715 C CB  . MET K 1 35 ? 120.880 96.270  99.099  1.00 46.59  ? 35 MET E  CB  1 
ATOM   2716 C CG  . MET K 1 35 ? 122.167 95.477  99.097  1.00 51.67  ? 35 MET E  CG  1 
ATOM   2717 S SD  . MET K 1 35 ? 122.346 94.416  100.533 1.00 73.51  ? 35 MET E  SD  1 
ATOM   2718 C CE  . MET K 1 35 ? 124.085 94.019  100.444 1.00 71.03  ? 35 MET E  CE  1 
ATOM   2719 N N   . VAL K 1 36 ? 123.270 98.440  100.165 1.00 48.97  ? 36 VAL E  N   1 
ATOM   2720 C CA  . VAL K 1 36 ? 124.612 98.927  99.874  1.00 50.21  ? 36 VAL E  CA  1 
ATOM   2721 C C   . VAL K 1 36 ? 125.596 97.874  100.358 1.00 56.88  ? 36 VAL E  C   1 
ATOM   2722 O O   . VAL K 1 36 ? 125.543 97.457  101.521 1.00 64.00  ? 36 VAL E  O   1 
ATOM   2723 C CB  . VAL K 1 36 ? 124.889 100.284 100.538 1.00 46.62  ? 36 VAL E  CB  1 
ATOM   2724 C CG1 . VAL K 1 36 ? 126.317 100.717 100.269 1.00 48.09  ? 36 VAL E  CG1 1 
ATOM   2725 C CG2 . VAL K 1 36 ? 123.907 101.327 100.038 1.00 41.47  ? 36 VAL E  CG2 1 
ATOM   2726 N N   . GLY K 1 37 ? 126.490 97.447  99.474  1.00 56.15  ? 37 GLY E  N   1 
ATOM   2727 C CA  . GLY K 1 37 ? 127.435 96.407  99.818  1.00 61.50  ? 37 GLY E  CA  1 
ATOM   2728 C C   . GLY K 1 37 ? 127.561 95.345  98.749  1.00 74.49  ? 37 GLY E  C   1 
ATOM   2729 O O   . GLY K 1 37 ? 127.972 95.637  97.623  1.00 81.43  ? 37 GLY E  O   1 
ATOM   2730 N N   . GLY K 1 38 ? 127.221 94.110  99.085  1.00 77.39  ? 38 GLY E  N   1 
ATOM   2731 C CA  . GLY K 1 38 ? 127.314 93.020  98.130  1.00 82.98  ? 38 GLY E  CA  1 
ATOM   2732 C C   . GLY K 1 38 ? 126.294 91.949  98.429  1.00 87.96  ? 38 GLY E  C   1 
ATOM   2733 O O   . GLY K 1 38 ? 126.053 91.600  99.588  1.00 86.27  ? 38 GLY E  O   1 
ATOM   2734 N N   . VAL K 1 39 ? 125.694 91.417  97.368  1.00 90.26  ? 39 VAL E  N   1 
ATOM   2735 C CA  . VAL K 1 39 ? 124.700 90.357  97.464  1.00 94.48  ? 39 VAL E  CA  1 
ATOM   2736 C C   . VAL K 1 39 ? 125.231 89.137  96.729  1.00 97.76  ? 39 VAL E  C   1 
ATOM   2737 O O   . VAL K 1 39 ? 125.553 89.215  95.538  1.00 93.80  ? 39 VAL E  O   1 
ATOM   2738 C CB  . VAL K 1 39 ? 123.342 90.796  96.886  1.00 91.47  ? 39 VAL E  CB  1 
ATOM   2739 C CG1 . VAL K 1 39 ? 122.455 89.589  96.638  1.00 90.96  ? 39 VAL E  CG1 1 
ATOM   2740 C CG2 . VAL K 1 39 ? 122.662 91.772  97.826  1.00 86.64  ? 39 VAL E  CG2 1 
ATOM   2741 N N   . VAL K 1 40 ? 125.326 88.017  97.438  1.00 101.84 ? 40 VAL E  N   1 
ATOM   2742 C CA  . VAL K 1 40 ? 125.763 86.748  96.869  1.00 102.74 ? 40 VAL E  CA  1 
ATOM   2743 C C   . VAL K 1 40 ? 124.630 85.750  97.042  1.00 105.52 ? 40 VAL E  C   1 
ATOM   2744 O O   . VAL K 1 40 ? 124.167 85.517  98.165  1.00 105.13 ? 40 VAL E  O   1 
ATOM   2745 C CB  . VAL K 1 40 ? 127.052 86.236  97.530  1.00 100.19 ? 40 VAL E  CB  1 
ATOM   2746 C CG1 . VAL K 1 40 ? 127.506 84.947  96.869  1.00 98.42  ? 40 VAL E  CG1 1 
ATOM   2747 C CG2 . VAL K 1 40 ? 128.142 87.291  97.452  1.00 97.85  ? 40 VAL E  CG2 1 
ATOM   2748 N N   . ILE K 1 41 ? 124.185 85.162  95.936  1.00 108.51 ? 41 ILE E  N   1 
ATOM   2749 C CA  . ILE K 1 41 ? 123.085 84.207  95.937  1.00 112.67 ? 41 ILE E  CA  1 
ATOM   2750 C C   . ILE K 1 41 ? 123.637 82.832  95.594  1.00 116.23 ? 41 ILE E  C   1 
ATOM   2751 O O   . ILE K 1 41 ? 124.323 82.664  94.578  1.00 115.97 ? 41 ILE E  O   1 
ATOM   2752 C CB  . ILE K 1 41 ? 121.986 84.621  94.945  1.00 112.79 ? 41 ILE E  CB  1 
ATOM   2753 C CG1 . ILE K 1 41 ? 121.585 86.078  95.176  1.00 107.76 ? 41 ILE E  CG1 1 
ATOM   2754 C CG2 . ILE K 1 41 ? 120.778 83.710  95.080  1.00 110.95 ? 41 ILE E  CG2 1 
ATOM   2755 C CD1 . ILE K 1 41 ? 120.631 86.612  94.138  1.00 104.16 ? 41 ILE E  CD1 1 
ATOM   2756 N N   . ALA K 1 42 ? 123.340 81.850  96.438  1.00 118.92 ? 42 ALA E  N   1 
ATOM   2757 C CA  . ALA K 1 42 ? 123.811 80.489  96.224  1.00 121.66 ? 42 ALA E  CA  1 
ATOM   2758 C C   . ALA K 1 42 ? 122.769 79.476  96.688  1.00 127.02 ? 42 ALA E  C   1 
ATOM   2759 O O   . ALA K 1 42 ? 121.823 79.819  97.396  1.00 129.60 ? 42 ALA E  O   1 
ATOM   2760 C CB  . ALA K 1 42 ? 125.129 80.265  96.946  1.00 117.58 ? 42 ALA E  CB  1 
ATOM   2761 O OXT . ALA K 1 42 ? 122.848 78.291  96.365  1.00 127.70 ? 42 ALA E  OXT 1 
ATOM   2762 N N   . GLY L 1 9  ? 135.739 104.490 93.532  1.00 75.58  ? 9  GLY F  N   1 
ATOM   2763 C CA  . GLY L 1 9  ? 134.779 105.022 94.481  1.00 77.59  ? 9  GLY F  CA  1 
ATOM   2764 C C   . GLY L 1 9  ? 133.464 105.415 93.841  1.00 77.76  ? 9  GLY F  C   1 
ATOM   2765 O O   . GLY L 1 9  ? 133.442 106.049 92.788  1.00 78.65  ? 9  GLY F  O   1 
ATOM   2766 N N   . TYR L 1 10 ? 132.361 105.038 94.481  1.00 74.83  ? 10 TYR F  N   1 
ATOM   2767 C CA  . TYR L 1 10 ? 131.022 105.324 93.985  1.00 70.87  ? 10 TYR F  CA  1 
ATOM   2768 C C   . TYR L 1 10 ? 130.410 106.443 94.813  1.00 65.85  ? 10 TYR F  C   1 
ATOM   2769 O O   . TYR L 1 10 ? 130.475 106.416 96.045  1.00 68.66  ? 10 TYR F  O   1 
ATOM   2770 C CB  . TYR L 1 10 ? 130.130 104.083 94.046  1.00 71.13  ? 10 TYR F  CB  1 
ATOM   2771 C CG  . TYR L 1 10 ? 130.624 102.904 93.238  1.00 81.03  ? 10 TYR F  CG  1 
ATOM   2772 C CD1 . TYR L 1 10 ? 131.577 103.064 92.241  1.00 83.11  ? 10 TYR F  CD1 1 
ATOM   2773 C CD2 . TYR L 1 10 ? 130.127 101.629 93.467  1.00 80.21  ? 10 TYR F  CD2 1 
ATOM   2774 C CE1 . TYR L 1 10 ? 132.028 101.987 91.505  1.00 84.09  ? 10 TYR F  CE1 1 
ATOM   2775 C CE2 . TYR L 1 10 ? 130.571 100.547 92.734  1.00 87.12  ? 10 TYR F  CE2 1 
ATOM   2776 C CZ  . TYR L 1 10 ? 131.520 100.732 91.754  1.00 91.17  ? 10 TYR F  CZ  1 
ATOM   2777 O OH  . TYR L 1 10 ? 131.964 99.656  91.021  1.00 91.09  ? 10 TYR F  OH  1 
ATOM   2778 N N   . GLU L 1 11 ? 129.821 107.424 94.137  1.00 61.80  ? 11 GLU F  N   1 
ATOM   2779 C CA  . GLU L 1 11 ? 129.129 108.532 94.789  1.00 57.88  ? 11 GLU F  CA  1 
ATOM   2780 C C   . GLU L 1 11 ? 127.716 108.592 94.224  1.00 52.72  ? 11 GLU F  C   1 
ATOM   2781 O O   . GLU L 1 11 ? 127.491 109.158 93.151  1.00 58.89  ? 11 GLU F  O   1 
ATOM   2782 C CB  . GLU L 1 11 ? 129.870 109.847 94.579  1.00 61.88  ? 11 GLU F  CB  1 
ATOM   2783 C CG  . GLU L 1 11 ? 129.547 110.901 95.620  1.00 65.71  ? 11 GLU F  CG  1 
ATOM   2784 C CD  . GLU L 1 11 ? 130.095 112.264 95.257  1.00 76.41  ? 11 GLU F  CD  1 
ATOM   2785 O OE1 . GLU L 1 11 ? 131.310 112.365 94.986  1.00 81.59  ? 11 GLU F  OE1 1 
ATOM   2786 O OE2 . GLU L 1 11 ? 129.312 113.237 95.248  1.00 75.54  ? 11 GLU F  OE2 1 
ATOM   2787 N N   . VAL L 1 12 ? 126.766 108.011 94.948  1.00 47.56  ? 12 VAL F  N   1 
ATOM   2788 C CA  . VAL L 1 12 ? 125.371 107.947 94.535  1.00 41.82  ? 12 VAL F  CA  1 
ATOM   2789 C C   . VAL L 1 12 ? 124.570 108.838 95.471  1.00 43.59  ? 12 VAL F  C   1 
ATOM   2790 O O   . VAL L 1 12 ? 124.632 108.670 96.694  1.00 54.65  ? 12 VAL F  O   1 
ATOM   2791 C CB  . VAL L 1 12 ? 124.846 106.505 94.561  1.00 38.02  ? 12 VAL F  CB  1 
ATOM   2792 C CG1 . VAL L 1 12 ? 123.450 106.434 93.985  1.00 36.81  ? 12 VAL F  CG1 1 
ATOM   2793 C CG2 . VAL L 1 12 ? 125.787 105.589 93.805  1.00 37.82  ? 12 VAL F  CG2 1 
ATOM   2794 N N   . HIS L 1 13 ? 123.822 109.786 94.912  1.00 39.40  ? 13 HIS F  N   1 
ATOM   2795 C CA  . HIS L 1 13 ? 123.012 110.655 95.751  1.00 42.52  ? 13 HIS F  CA  1 
ATOM   2796 C C   . HIS L 1 13 ? 121.806 111.167 94.980  1.00 39.69  ? 13 HIS F  C   1 
ATOM   2797 O O   . HIS L 1 13 ? 121.738 111.067 93.757  1.00 38.87  ? 13 HIS F  O   1 
ATOM   2798 C CB  . HIS L 1 13 ? 123.818 111.831 96.319  1.00 45.91  ? 13 HIS F  CB  1 
ATOM   2799 C CG  . HIS L 1 13 ? 124.727 112.493 95.332  1.00 46.41  ? 13 HIS F  CG  1 
ATOM   2800 N ND1 . HIS L 1 13 ? 124.570 113.806 94.947  1.00 43.92  ? 13 HIS F  ND1 1 
ATOM   2801 C CD2 . HIS L 1 13 ? 125.824 112.039 94.682  1.00 49.27  ? 13 HIS F  CD2 1 
ATOM   2802 C CE1 . HIS L 1 13 ? 125.518 114.127 94.086  1.00 48.42  ? 13 HIS F  CE1 1 
ATOM   2803 N NE2 . HIS L 1 13 ? 126.292 113.072 93.907  1.00 50.84  ? 13 HIS F  NE2 1 
ATOM   2804 N N   . HIS L 1 14 ? 120.836 111.690 95.730  1.00 39.43  ? 14 HIS F  N   1 
ATOM   2805 C CA  . HIS L 1 14 ? 119.645 112.339 95.184  1.00 36.41  ? 14 HIS F  CA  1 
ATOM   2806 C C   . HIS L 1 14 ? 118.865 111.404 94.259  1.00 34.91  ? 14 HIS F  C   1 
ATOM   2807 O O   . HIS L 1 14 ? 118.719 111.645 93.065  1.00 41.49  ? 14 HIS F  O   1 
ATOM   2808 C CB  . HIS L 1 14 ? 120.016 113.642 94.475  1.00 37.87  ? 14 HIS F  CB  1 
ATOM   2809 C CG  . HIS L 1 14 ? 120.521 114.701 95.401  1.00 43.65  ? 14 HIS F  CG  1 
ATOM   2810 N ND1 . HIS L 1 14 ? 121.858 114.850 95.701  1.00 45.90  ? 14 HIS F  ND1 1 
ATOM   2811 C CD2 . HIS L 1 14 ? 119.867 115.648 96.112  1.00 47.98  ? 14 HIS F  CD2 1 
ATOM   2812 C CE1 . HIS L 1 14 ? 122.006 115.852 96.548  1.00 53.85  ? 14 HIS F  CE1 1 
ATOM   2813 N NE2 . HIS L 1 14 ? 120.814 116.353 96.814  1.00 57.15  ? 14 HIS F  NE2 1 
ATOM   2814 N N   . GLN L 1 15 ? 118.351 110.327 94.841  1.00 31.09  ? 15 GLN F  N   1 
ATOM   2815 C CA  . GLN L 1 15 ? 117.535 109.362 94.120  1.00 25.82  ? 15 GLN F  CA  1 
ATOM   2816 C C   . GLN L 1 15 ? 116.137 109.335 94.715  1.00 27.11  ? 15 GLN F  C   1 
ATOM   2817 O O   . GLN L 1 15 ? 115.981 109.243 95.935  1.00 36.68  ? 15 GLN F  O   1 
ATOM   2818 C CB  . GLN L 1 15 ? 118.153 107.967 94.174  1.00 26.86  ? 15 GLN F  CB  1 
ATOM   2819 C CG  . GLN L 1 15 ? 118.979 107.622 92.962  1.00 36.02  ? 15 GLN F  CG  1 
ATOM   2820 C CD  . GLN L 1 15 ? 120.423 108.010 93.131  1.00 36.75  ? 15 GLN F  CD  1 
ATOM   2821 O OE1 . GLN L 1 15 ? 120.869 108.305 94.237  1.00 32.60  ? 15 GLN F  OE1 1 
ATOM   2822 N NE2 . GLN L 1 15 ? 121.166 108.020 92.034  1.00 36.88  ? 15 GLN F  NE2 1 
ATOM   2823 N N   . LYS L 1 16 ? 115.129 109.418 93.855  1.00 25.46  ? 16 LYS F  N   1 
ATOM   2824 C CA  . LYS L 1 16 ? 113.733 109.261 94.251  1.00 23.75  ? 16 LYS F  CA  1 
ATOM   2825 C C   . LYS L 1 16 ? 113.216 108.003 93.568  1.00 27.50  ? 16 LYS F  C   1 
ATOM   2826 O O   . LYS L 1 16 ? 112.889 108.024 92.379  1.00 37.91  ? 16 LYS F  O   1 
ATOM   2827 C CB  . LYS L 1 16 ? 112.906 110.481 93.872  1.00 23.54  ? 16 LYS F  CB  1 
ATOM   2828 C CG  . LYS L 1 16 ? 113.427 111.772 94.447  1.00 20.89  ? 16 LYS F  CG  1 
ATOM   2829 C CD  . LYS L 1 16 ? 112.466 112.903 94.178  1.00 22.06  ? 16 LYS F  CD  1 
ATOM   2830 C CE  . LYS L 1 16 ? 112.952 114.186 94.806  1.00 22.83  ? 16 LYS F  CE  1 
ATOM   2831 N NZ  . LYS L 1 16 ? 111.873 115.201 94.828  1.00 28.31  ? 16 LYS F  NZ  1 
ATOM   2832 N N   . LEU L 1 17 ? 113.142 106.909 94.317  1.00 23.96  ? 17 LEU F  N   1 
ATOM   2833 C CA  . LEU L 1 17 ? 112.800 105.606 93.772  1.00 25.08  ? 17 LEU F  CA  1 
ATOM   2834 C C   . LEU L 1 17 ? 111.473 105.141 94.347  1.00 25.06  ? 17 LEU F  C   1 
ATOM   2835 O O   . LEU L 1 17 ? 111.270 105.184 95.563  1.00 32.20  ? 17 LEU F  O   1 
ATOM   2836 C CB  . LEU L 1 17 ? 113.896 104.586 94.080  1.00 25.85  ? 17 LEU F  CB  1 
ATOM   2837 C CG  . LEU L 1 17 ? 113.877 103.289 93.275  1.00 28.96  ? 17 LEU F  CG  1 
ATOM   2838 C CD1 . LEU L 1 17 ? 115.282 102.938 92.838  1.00 37.70  ? 17 LEU F  CD1 1 
ATOM   2839 C CD2 . LEU L 1 17 ? 113.272 102.159 94.085  1.00 27.85  ? 17 LEU F  CD2 1 
ATOM   2840 N N   . VAL L 1 18 ? 110.571 104.705 93.474  1.00 24.89  ? 18 VAL F  N   1 
ATOM   2841 C CA  . VAL L 1 18 ? 109.323 104.067 93.871  1.00 26.58  ? 18 VAL F  CA  1 
ATOM   2842 C C   . VAL L 1 18 ? 109.288 102.683 93.245  1.00 29.85  ? 18 VAL F  C   1 
ATOM   2843 O O   . VAL L 1 18 ? 109.460 102.543 92.030  1.00 35.03  ? 18 VAL F  O   1 
ATOM   2844 C CB  . VAL L 1 18 ? 108.094 104.891 93.452  1.00 25.75  ? 18 VAL F  CB  1 
ATOM   2845 C CG1 . VAL L 1 18 ? 106.862 104.374 94.157  1.00 24.22  ? 18 VAL F  CG1 1 
ATOM   2846 C CG2 . VAL L 1 18 ? 108.305 106.354 93.772  1.00 24.63  ? 18 VAL F  CG2 1 
ATOM   2847 N N   . PHE L 1 19 ? 109.069 101.667 94.072  1.00 30.43  ? 19 PHE F  N   1 
ATOM   2848 C CA  . PHE L 1 19 ? 109.128 100.275 93.648  1.00 32.79  ? 19 PHE F  CA  1 
ATOM   2849 C C   . PHE L 1 19 ? 107.802 99.604  93.967  1.00 36.31  ? 19 PHE F  C   1 
ATOM   2850 O O   . PHE L 1 19 ? 107.426 99.494  95.137  1.00 43.04  ? 19 PHE F  O   1 
ATOM   2851 C CB  . PHE L 1 19 ? 110.282 99.552  94.344  1.00 36.08  ? 19 PHE F  CB  1 
ATOM   2852 C CG  . PHE L 1 19 ? 110.683 98.267  93.687  1.00 38.70  ? 19 PHE F  CG  1 
ATOM   2853 C CD1 . PHE L 1 19 ? 109.908 97.130  93.825  1.00 38.82  ? 19 PHE F  CD1 1 
ATOM   2854 C CD2 . PHE L 1 19 ? 111.844 98.190  92.945  1.00 41.78  ? 19 PHE F  CD2 1 
ATOM   2855 C CE1 . PHE L 1 19 ? 110.278 95.947  93.226  1.00 39.93  ? 19 PHE F  CE1 1 
ATOM   2856 C CE2 . PHE L 1 19 ? 112.219 97.009  92.344  1.00 44.10  ? 19 PHE F  CE2 1 
ATOM   2857 C CZ  . PHE L 1 19 ? 111.435 95.887  92.486  1.00 44.51  ? 19 PHE F  CZ  1 
ATOM   2858 N N   . PHE L 1 20 ? 107.101 99.157  92.932  1.00 35.86  ? 20 PHE F  N   1 
ATOM   2859 C CA  . PHE L 1 20 ? 105.872 98.390  93.079  1.00 37.59  ? 20 PHE F  CA  1 
ATOM   2860 C C   . PHE L 1 20 ? 106.154 96.939  92.727  1.00 45.25  ? 20 PHE F  C   1 
ATOM   2861 O O   . PHE L 1 20 ? 106.763 96.656  91.692  1.00 55.23  ? 20 PHE F  O   1 
ATOM   2862 C CB  . PHE L 1 20 ? 104.763 98.931  92.178  1.00 39.09  ? 20 PHE F  CB  1 
ATOM   2863 C CG  . PHE L 1 20 ? 104.272 100.292 92.559  1.00 38.58  ? 20 PHE F  CG  1 
ATOM   2864 C CD1 . PHE L 1 20 ? 104.859 101.425 92.032  1.00 36.65  ? 20 PHE F  CD1 1 
ATOM   2865 C CD2 . PHE L 1 20 ? 103.207 100.440 93.426  1.00 35.18  ? 20 PHE F  CD2 1 
ATOM   2866 C CE1 . PHE L 1 20 ? 104.401 102.676 92.371  1.00 33.87  ? 20 PHE F  CE1 1 
ATOM   2867 C CE2 . PHE L 1 20 ? 102.747 101.691 93.768  1.00 34.77  ? 20 PHE F  CE2 1 
ATOM   2868 C CZ  . PHE L 1 20 ? 103.345 102.810 93.241  1.00 31.87  ? 20 PHE F  CZ  1 
ATOM   2869 N N   . ALA L 1 21 ? 105.717 96.026  93.585  1.00 46.71  ? 21 ALA F  N   1 
ATOM   2870 C CA  . ALA L 1 21 ? 105.852 94.600  93.336  1.00 51.62  ? 21 ALA F  CA  1 
ATOM   2871 C C   . ALA L 1 21 ? 104.526 93.916  93.619  1.00 59.08  ? 21 ALA F  C   1 
ATOM   2872 O O   . ALA L 1 21 ? 103.855 94.229  94.605  1.00 64.50  ? 21 ALA F  O   1 
ATOM   2873 C CB  . ALA L 1 21 ? 106.959 93.983  94.194  1.00 47.68  ? 21 ALA F  CB  1 
ATOM   2874 N N   . GLU L 1 22 ? 104.147 92.991  92.747  1.00 62.23  ? 22 GLU F  N   1 
ATOM   2875 C CA  . GLU L 1 22 ? 102.912 92.241  92.926  1.00 69.45  ? 22 GLU F  CA  1 
ATOM   2876 C C   . GLU L 1 22 ? 103.150 90.754  92.725  1.00 74.34  ? 22 GLU F  C   1 
ATOM   2877 O O   . GLU L 1 22 ? 104.010 90.355  91.944  1.00 78.12  ? 22 GLU F  O   1 
ATOM   2878 C CB  . GLU L 1 22 ? 101.836 92.735  91.964  1.00 72.05  ? 22 GLU F  CB  1 
ATOM   2879 C CG  . GLU L 1 22 ? 101.118 93.978  92.437  1.00 71.84  ? 22 GLU F  CG  1 
ATOM   2880 C CD  . GLU L 1 22 ? 99.693  93.697  92.863  1.00 75.14  ? 22 GLU F  CD  1 
ATOM   2881 O OE1 . GLU L 1 22 ? 99.332  92.507  92.981  1.00 75.71  ? 22 GLU F  OE1 1 
ATOM   2882 O OE2 . GLU L 1 22 ? 98.933  94.664  93.080  1.00 74.25  ? 22 GLU F  OE2 1 
HETATM 2883 N N   . DAS L 1 23 ? 102.379 89.938  93.432  1.00 72.71  ? 23 DAS F  N   1 
HETATM 2884 C CA  . DAS L 1 23 ? 102.538 88.496  93.365  1.00 76.75  ? 23 DAS F  CA  1 
HETATM 2885 C C   . DAS L 1 23 ? 103.837 88.099  94.052  1.00 76.02  ? 23 DAS F  C   1 
HETATM 2886 O O   . DAS L 1 23 ? 103.871 87.918  95.268  1.00 76.84  ? 23 DAS F  O   1 
HETATM 2887 C CB  . DAS L 1 23 ? 101.352 87.800  94.032  1.00 83.90  ? 23 DAS F  CB  1 
HETATM 2888 C CG  . DAS L 1 23 ? 101.331 86.306  93.777  1.00 88.14  ? 23 DAS F  CG  1 
HETATM 2889 O OD1 . DAS L 1 23 ? 102.149 85.826  92.964  1.00 87.21  ? 23 DAS F  OD1 1 
HETATM 2890 O OD2 . DAS L 1 23 ? 100.495 85.610  94.390  1.00 86.54  ? 23 DAS F  OD2 1 
ATOM   2891 N N   . VAL L 1 24 ? 104.901 87.980  93.261  1.00 73.27  ? 24 VAL F  N   1 
ATOM   2892 C CA  . VAL L 1 24 ? 106.225 87.608  93.753  1.00 69.90  ? 24 VAL F  CA  1 
ATOM   2893 C C   . VAL L 1 24 ? 106.161 86.342  94.603  1.00 67.77  ? 24 VAL F  C   1 
ATOM   2894 O O   . VAL L 1 24 ? 106.351 86.386  95.815  1.00 70.39  ? 24 VAL F  O   1 
ATOM   2895 C CB  . VAL L 1 24 ? 106.871 88.760  94.541  1.00 64.79  ? 24 VAL F  CB  1 
ATOM   2896 C CG1 . VAL L 1 24 ? 108.347 88.493  94.748  1.00 56.42  ? 24 VAL F  CG1 1 
ATOM   2897 C CG2 . VAL L 1 24 ? 106.672 90.076  93.813  1.00 58.59  ? 24 VAL F  CG2 1 
ATOM   2898 N N   . GLY L 1 25 ? 105.887 85.210  93.960  1.00 65.16  ? 25 GLY F  N   1 
ATOM   2899 C CA  . GLY L 1 25 ? 105.751 83.945  94.656  1.00 63.72  ? 25 GLY F  CA  1 
ATOM   2900 C C   . GLY L 1 25 ? 107.008 83.106  94.522  1.00 65.69  ? 25 GLY F  C   1 
ATOM   2901 O O   . GLY L 1 25 ? 107.578 82.990  93.435  1.00 67.63  ? 25 GLY F  O   1 
ATOM   2902 N N   . SER L 1 26 ? 107.428 82.523  95.644  1.00 66.41  ? 26 SER F  N   1 
ATOM   2903 C CA  . SER L 1 26 ? 108.562 81.600  95.689  1.00 66.74  ? 26 SER F  CA  1 
ATOM   2904 C C   . SER L 1 26 ? 109.824 82.234  95.108  1.00 62.57  ? 26 SER F  C   1 
ATOM   2905 O O   . SER L 1 26 ? 110.552 81.623  94.324  1.00 59.58  ? 26 SER F  O   1 
ATOM   2906 C CB  . SER L 1 26 ? 108.225 80.291  94.972  1.00 65.12  ? 26 SER F  CB  1 
ATOM   2907 O OG  . SER L 1 26 ? 106.864 79.946  95.157  1.00 62.29  ? 26 SER F  OG  1 
ATOM   2908 N N   . ASN L 1 27 ? 110.081 83.477  95.501  1.00 58.74  ? 27 ASN F  N   1 
ATOM   2909 C CA  . ASN L 1 27 ? 111.281 84.171  95.053  1.00 53.96  ? 27 ASN F  CA  1 
ATOM   2910 C C   . ASN L 1 27 ? 112.506 83.572  95.730  1.00 54.07  ? 27 ASN F  C   1 
ATOM   2911 O O   . ASN L 1 27 ? 112.601 83.562  96.961  1.00 61.28  ? 27 ASN F  O   1 
ATOM   2912 C CB  . ASN L 1 27 ? 111.176 85.662  95.357  1.00 53.66  ? 27 ASN F  CB  1 
ATOM   2913 C CG  . ASN L 1 27 ? 112.529 86.342  95.403  1.00 48.69  ? 27 ASN F  CG  1 
ATOM   2914 O OD1 . ASN L 1 27 ? 113.281 86.319  94.432  1.00 46.96  ? 27 ASN F  OD1 1 
ATOM   2915 N ND2 . ASN L 1 27 ? 112.847 86.951  96.537  1.00 48.76  ? 27 ASN F  ND2 1 
ATOM   2916 N N   . LYS L 1 28 ? 113.441 83.068  94.929  1.00 49.39  ? 28 LYS F  N   1 
ATOM   2917 C CA  . LYS L 1 28 ? 114.696 82.537  95.435  1.00 50.70  ? 28 LYS F  CA  1 
ATOM   2918 C C   . LYS L 1 28 ? 115.882 83.438  95.130  1.00 50.43  ? 28 LYS F  C   1 
ATOM   2919 O O   . LYS L 1 28 ? 117.012 83.098  95.495  1.00 47.12  ? 28 LYS F  O   1 
ATOM   2920 C CB  . LYS L 1 28 ? 114.949 81.138  94.863  1.00 51.94  ? 28 LYS F  CB  1 
ATOM   2921 C CG  . LYS L 1 28 ? 113.794 80.178  95.066  1.00 54.88  ? 28 LYS F  CG  1 
ATOM   2922 C CD  . LYS L 1 28 ? 114.272 78.738  95.084  1.00 56.29  ? 28 LYS F  CD  1 
ATOM   2923 C CE  . LYS L 1 28 ? 113.102 77.771  95.135  1.00 61.55  ? 28 LYS F  CE  1 
ATOM   2924 N NZ  . LYS L 1 28 ? 111.794 78.480  95.126  1.00 55.99  ? 28 LYS F  NZ  1 
ATOM   2925 N N   . GLY L 1 29 ? 115.659 84.573  94.468  1.00 54.52  ? 29 GLY F  N   1 
ATOM   2926 C CA  . GLY L 1 29 ? 116.701 85.509  94.149  1.00 50.66  ? 29 GLY F  CA  1 
ATOM   2927 C C   . GLY L 1 29 ? 116.605 86.785  94.957  1.00 49.00  ? 29 GLY F  C   1 
ATOM   2928 O O   . GLY L 1 29 ? 115.927 86.855  95.991  1.00 48.69  ? 29 GLY F  O   1 
ATOM   2929 N N   . ALA L 1 30 ? 117.288 87.816  94.474  1.00 48.30  ? 30 ALA F  N   1 
ATOM   2930 C CA  . ALA L 1 30 ? 117.339 89.111  95.137  1.00 41.05  ? 30 ALA F  CA  1 
ATOM   2931 C C   . ALA L 1 30 ? 116.445 90.092  94.393  1.00 40.65  ? 30 ALA F  C   1 
ATOM   2932 O O   . ALA L 1 30 ? 116.604 90.287  93.184  1.00 43.98  ? 30 ALA F  O   1 
ATOM   2933 C CB  . ALA L 1 30 ? 118.772 89.635  95.201  1.00 35.72  ? 30 ALA F  CB  1 
ATOM   2934 N N   . ILE L 1 31 ? 115.513 90.706  95.113  1.00 38.51  ? 31 ILE F  N   1 
ATOM   2935 C CA  . ILE L 1 31 ? 114.661 91.761  94.581  1.00 37.05  ? 31 ILE F  CA  1 
ATOM   2936 C C   . ILE L 1 31 ? 115.007 93.034  95.336  1.00 40.18  ? 31 ILE F  C   1 
ATOM   2937 O O   . ILE L 1 31 ? 114.643 93.189  96.508  1.00 49.66  ? 31 ILE F  O   1 
ATOM   2938 C CB  . ILE L 1 31 ? 113.174 91.419  94.715  1.00 33.50  ? 31 ILE F  CB  1 
ATOM   2939 C CG1 . ILE L 1 31 ? 112.863 90.139  93.944  1.00 38.10  ? 31 ILE F  CG1 1 
ATOM   2940 C CG2 . ILE L 1 31 ? 112.318 92.571  94.222  1.00 30.82  ? 31 ILE F  CG2 1 
ATOM   2941 C CD1 . ILE L 1 31 ? 111.401 89.909  93.722  1.00 42.08  ? 31 ILE F  CD1 1 
ATOM   2942 N N   . ILE L 1 32 ? 115.708 93.947  94.673  1.00 37.80  ? 32 ILE F  N   1 
ATOM   2943 C CA  . ILE L 1 32 ? 116.253 95.138  95.310  1.00 42.84  ? 32 ILE F  CA  1 
ATOM   2944 C C   . ILE L 1 32 ? 115.716 96.370  94.600  1.00 42.30  ? 32 ILE F  C   1 
ATOM   2945 O O   . ILE L 1 32 ? 115.638 96.404  93.369  1.00 45.16  ? 32 ILE F  O   1 
ATOM   2946 C CB  . ILE L 1 32 ? 117.795 95.129  95.300  1.00 44.85  ? 32 ILE F  CB  1 
ATOM   2947 C CG1 . ILE L 1 32 ? 118.323 93.787  95.804  1.00 42.64  ? 32 ILE F  CG1 1 
ATOM   2948 C CG2 . ILE L 1 32 ? 118.336 96.252  96.156  1.00 48.55  ? 32 ILE F  CG2 1 
ATOM   2949 C CD1 . ILE L 1 32 ? 119.521 93.278  95.044  1.00 40.67  ? 32 ILE F  CD1 1 
ATOM   2950 N N   . GLY L 1 33 ? 115.333 97.376  95.379  1.00 44.70  ? 33 GLY F  N   1 
ATOM   2951 C CA  . GLY L 1 33 ? 114.908 98.638  94.812  1.00 40.70  ? 33 GLY F  CA  1 
ATOM   2952 C C   . GLY L 1 33 ? 116.079 99.446  94.297  1.00 40.23  ? 33 GLY F  C   1 
ATOM   2953 O O   . GLY L 1 33 ? 116.153 99.756  93.106  1.00 43.73  ? 33 GLY F  O   1 
ATOM   2954 N N   . LEU L 1 34 ? 117.001 99.797  95.187  1.00 41.37  ? 34 LEU F  N   1 
ATOM   2955 C CA  . LEU L 1 34 ? 118.233 100.482 94.819  1.00 41.56  ? 34 LEU F  CA  1 
ATOM   2956 C C   . LEU L 1 34 ? 119.396 99.697  95.398  1.00 43.59  ? 34 LEU F  C   1 
ATOM   2957 O O   . LEU L 1 34 ? 119.452 99.475  96.610  1.00 52.62  ? 34 LEU F  O   1 
ATOM   2958 C CB  . LEU L 1 34 ? 118.247 101.922 95.338  1.00 42.98  ? 34 LEU F  CB  1 
ATOM   2959 C CG  . LEU L 1 34 ? 119.288 102.859 94.726  1.00 39.98  ? 34 LEU F  CG  1 
ATOM   2960 C CD1 . LEU L 1 34 ? 118.641 104.174 94.339  1.00 33.09  ? 34 LEU F  CD1 1 
ATOM   2961 C CD2 . LEU L 1 34 ? 120.452 103.088 95.670  1.00 40.03  ? 34 LEU F  CD2 1 
ATOM   2962 N N   . MET L 1 35 ? 120.321 99.280  94.541  1.00 38.84  ? 35 MET F  N   1 
ATOM   2963 C CA  . MET L 1 35 ? 121.468 98.488  94.955  1.00 44.10  ? 35 MET F  CA  1 
ATOM   2964 C C   . MET L 1 35 ? 122.745 99.181  94.508  1.00 48.26  ? 35 MET F  C   1 
ATOM   2965 O O   . MET L 1 35 ? 122.880 99.541  93.336  1.00 57.64  ? 35 MET F  O   1 
ATOM   2966 C CB  . MET L 1 35 ? 121.401 97.078  94.371  1.00 46.59  ? 35 MET F  CB  1 
ATOM   2967 C CG  . MET L 1 35 ? 122.728 96.354  94.370  1.00 51.67  ? 35 MET F  CG  1 
ATOM   2968 S SD  . MET L 1 35 ? 122.961 95.303  95.806  1.00 73.51  ? 35 MET F  SD  1 
ATOM   2969 C CE  . MET L 1 35 ? 124.720 94.999  95.718  1.00 71.03  ? 35 MET F  CE  1 
ATOM   2970 N N   . VAL L 1 36 ? 123.672 99.370  95.440  1.00 48.97  ? 36 VAL F  N   1 
ATOM   2971 C CA  . VAL L 1 36 ? 124.987 99.928  95.151  1.00 50.21  ? 36 VAL F  CA  1 
ATOM   2972 C C   . VAL L 1 36 ? 126.025 98.929  95.635  1.00 56.88  ? 36 VAL F  C   1 
ATOM   2973 O O   . VAL L 1 36 ? 125.993 98.509  96.798  1.00 64.00  ? 36 VAL F  O   1 
ATOM   2974 C CB  . VAL L 1 36 ? 125.192 101.297 95.816  1.00 46.62  ? 36 VAL F  CB  1 
ATOM   2975 C CG1 . VAL L 1 36 ? 126.595 101.806 95.548  1.00 48.09  ? 36 VAL F  CG1 1 
ATOM   2976 C CG2 . VAL L 1 36 ? 124.157 102.287 95.315  1.00 41.47  ? 36 VAL F  CG2 1 
ATOM   2977 N N   . GLY L 1 37 ? 126.941 98.550  94.751  1.00 56.15  ? 37 GLY F  N   1 
ATOM   2978 C CA  . GLY L 1 37 ? 127.939 97.560  95.096  1.00 61.50  ? 37 GLY F  CA  1 
ATOM   2979 C C   . GLY L 1 37 ? 128.121 96.506  94.026  1.00 74.49  ? 37 GLY F  C   1 
ATOM   2980 O O   . GLY L 1 37 ? 128.518 96.820  92.901  1.00 81.43  ? 37 GLY F  O   1 
ATOM   2981 N N   . GLY L 1 38 ? 127.848 95.256  94.362  1.00 77.39  ? 38 GLY F  N   1 
ATOM   2982 C CA  . GLY L 1 38 ? 127.999 94.173  93.406  1.00 82.98  ? 38 GLY F  CA  1 
ATOM   2983 C C   . GLY L 1 38 ? 127.036 93.049  93.704  1.00 87.96  ? 38 GLY F  C   1 
ATOM   2984 O O   . GLY L 1 38 ? 126.813 92.687  94.863  1.00 86.27  ? 38 GLY F  O   1 
ATOM   2985 N N   . VAL L 1 39 ? 126.466 92.487  92.642  1.00 90.26  ? 39 VAL F  N   1 
ATOM   2986 C CA  . VAL L 1 39 ? 125.529 91.376  92.737  1.00 94.48  ? 39 VAL F  CA  1 
ATOM   2987 C C   . VAL L 1 39 ? 126.125 90.186  92.001  1.00 97.76  ? 39 VAL F  C   1 
ATOM   2988 O O   . VAL L 1 39 ? 126.443 90.281  90.811  1.00 93.80  ? 39 VAL F  O   1 
ATOM   2989 C CB  . VAL L 1 39 ? 124.150 91.743  92.158  1.00 91.47  ? 39 VAL F  CB  1 
ATOM   2990 C CG1 . VAL L 1 39 ? 123.329 90.491  91.908  1.00 90.96  ? 39 VAL F  CG1 1 
ATOM   2991 C CG2 . VAL L 1 39 ? 123.418 92.681  93.098  1.00 86.64  ? 39 VAL F  CG2 1 
ATOM   2992 N N   . VAL L 1 40 ? 126.278 89.072  92.710  1.00 101.84 ? 40 VAL F  N   1 
ATOM   2993 C CA  . VAL L 1 40 ? 126.782 87.828  92.141  1.00 102.74 ? 40 VAL F  CA  1 
ATOM   2994 C C   . VAL L 1 40 ? 125.702 86.772  92.312  1.00 105.52 ? 40 VAL F  C   1 
ATOM   2995 O O   . VAL L 1 40 ? 125.252 86.514  93.435  1.00 105.13 ? 40 VAL F  O   1 
ATOM   2996 C CB  . VAL L 1 40 ? 128.095 87.384  92.803  1.00 100.19 ? 40 VAL F  CB  1 
ATOM   2997 C CG1 . VAL L 1 40 ? 128.617 86.121  92.142  1.00 98.42  ? 40 VAL F  CG1 1 
ATOM   2998 C CG2 . VAL L 1 40 ? 129.128 88.495  92.727  1.00 97.85  ? 40 VAL F  CG2 1 
ATOM   2999 N N   . ILE L 1 41 ? 125.290 86.162  91.206  1.00 108.51 ? 41 ILE F  N   1 
ATOM   3000 C CA  . ILE L 1 41 ? 124.242 85.149  91.205  1.00 112.67 ? 41 ILE F  CA  1 
ATOM   3001 C C   . ILE L 1 41 ? 124.865 83.806  90.863  1.00 116.23 ? 41 ILE F  C   1 
ATOM   3002 O O   . ILE L 1 41 ? 125.561 83.674  89.847  1.00 115.97 ? 41 ILE F  O   1 
ATOM   3003 C CB  . ILE L 1 41 ? 123.123 85.506  90.213  1.00 112.79 ? 41 ILE F  CB  1 
ATOM   3004 C CG1 . ILE L 1 41 ? 122.646 86.939  90.444  1.00 107.76 ? 41 ILE F  CG1 1 
ATOM   3005 C CG2 . ILE L 1 41 ? 121.965 84.533  90.346  1.00 110.95 ? 41 ILE F  CG2 1 
ATOM   3006 C CD1 . ILE L 1 41 ? 121.665 87.423  89.406  1.00 104.16 ? 41 ILE F  CD1 1 
ATOM   3007 N N   . ALA L 1 42 ? 124.620 82.809  91.706  1.00 118.92 ? 42 ALA F  N   1 
ATOM   3008 C CA  . ALA L 1 42 ? 125.162 81.475  91.492  1.00 121.66 ? 42 ALA F  CA  1 
ATOM   3009 C C   . ALA L 1 42 ? 124.175 80.408  91.954  1.00 127.02 ? 42 ALA F  C   1 
ATOM   3010 O O   . ALA L 1 42 ? 123.211 80.701  92.661  1.00 129.60 ? 42 ALA F  O   1 
ATOM   3011 C CB  . ALA L 1 42 ? 126.490 81.321  92.215  1.00 117.58 ? 42 ALA F  CB  1 
ATOM   3012 O OXT . ALA L 1 42 ? 124.317 79.229  91.631  1.00 127.70 ? 42 ALA F  OXT 1 
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