data_9JA6
# 
_entry.id   9JA6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JA6         pdb_00009ja6 10.2210/pdb9ja6/pdb 
WWPDB D_1300030808 ?            ?                   
EMDB  EMD-61291    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JA6 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Tdk1 tetramer complex' 
_pdbx_database_related.db_id          EMD-61291 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yekeqiong@ibp.ac.cn 
_pdbx_contact_author.name_first         Keqiong 
_pdbx_contact_author.name_last          Ye 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6169-7049 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, J.' 1 0000-0002-1864-7510 
'Ye, K.'    2 0000-0001-6169-7049 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            121 
_citation.language                  ? 
_citation.page_first                e2408618121 
_citation.page_last                 e2408618121 
_citation.title                     
'Structural duality enables a single protein to act as a toxin-antidote pair for meiotic drive.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2408618121 
_citation.pdbx_database_id_PubMed   39485800 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hua, Y.'    1 ?                   
primary 'Zhang, J.'  2 0000-0002-1864-7510 
primary 'Yang, M.Y.' 3 ?                   
primary 'Ren, J.Y.'  4 ?                   
primary 'Suo, F.'    5 0000-0001-6526-5489 
primary 'Liang, L.'  6 ?                   
primary 'Dong, M.Q.' 7 0000-0002-6094-1182 
primary 'Ye, K.'     8 0000-0001-6169-7049 
primary 'Du, L.L.'   9 0000-0002-1028-7397 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Meiotically up-regulated gene 135 protein,Immunoglobulin G-binding protein G' 
_entity.formula_weight             38436.680 
_entity.pdbx_number_of_molecules   4 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'IgG-binding protein G' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSEEDNRLNELFANDLGVQPPCERSLKEGRRFLNDFEIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDND
ECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFRREMGEWKKAREEDKEWRKSTDERLENLLNIVREILDVQRDMRNDL
SNLTRKVDRMDMRLSRNNNMIMRSFRQPITEVPFFNGDIPDPNLPRITRIEDIDSLSEENCTRYLKGYGVSYDENDQSLW
KRQLAKAVGLTAAYDASYTFSPFSSSESGGGSSGGGSTYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWT
YDDATKTFTVTE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSEEDNRLNELFANDLGVQPPCERSLKEGRRFLNDFEIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDND
ECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFRREMGEWKKAREEDKEWRKSTDERLENLLNIVREILDVQRDMRNDL
SNLTRKVDRMDMRLSRNNNMIMRSFRQPITEVPFFNGDIPDPNLPRITRIEDIDSLSEENCTRYLKGYGVSYDENDQSLW
KRQLAKAVGLTAAYDASYTFSPFSSSESGGGSSGGGSTYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWT
YDDATKTFTVTE
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   GLU n 
1 4   GLU n 
1 5   ASP n 
1 6   ASN n 
1 7   ARG n 
1 8   LEU n 
1 9   ASN n 
1 10  GLU n 
1 11  LEU n 
1 12  PHE n 
1 13  ALA n 
1 14  ASN n 
1 15  ASP n 
1 16  LEU n 
1 17  GLY n 
1 18  VAL n 
1 19  GLN n 
1 20  PRO n 
1 21  PRO n 
1 22  CYS n 
1 23  GLU n 
1 24  ARG n 
1 25  SER n 
1 26  LEU n 
1 27  LYS n 
1 28  GLU n 
1 29  GLY n 
1 30  ARG n 
1 31  ARG n 
1 32  PHE n 
1 33  LEU n 
1 34  ASN n 
1 35  ASP n 
1 36  PHE n 
1 37  GLU n 
1 38  ILE n 
1 39  ALA n 
1 40  ALA n 
1 41  LYS n 
1 42  LYS n 
1 43  LYS n 
1 44  LEU n 
1 45  LEU n 
1 46  GLU n 
1 47  LEU n 
1 48  GLU n 
1 49  ARG n 
1 50  LYS n 
1 51  ALA n 
1 52  LEU n 
1 53  GLU n 
1 54  ASP n 
1 55  LYS n 
1 56  GLU n 
1 57  LYS n 
1 58  ASN n 
1 59  LEU n 
1 60  ASN n 
1 61  PHE n 
1 62  VAL n 
1 63  VAL n 
1 64  GLU n 
1 65  SER n 
1 66  GLU n 
1 67  ARG n 
1 68  THR n 
1 69  LEU n 
1 70  PHE n 
1 71  ASN n 
1 72  SER n 
1 73  LYS n 
1 74  LYS n 
1 75  ARG n 
1 76  ALA n 
1 77  PHE n 
1 78  ASP n 
1 79  ASN n 
1 80  ASP n 
1 81  GLU n 
1 82  CYS n 
1 83  TYR n 
1 84  ASN n 
1 85  ASP n 
1 86  ARG n 
1 87  CYS n 
1 88  LYS n 
1 89  LEU n 
1 90  PHE n 
1 91  ARG n 
1 92  GLY n 
1 93  ILE n 
1 94  VAL n 
1 95  ASN n 
1 96  GLU n 
1 97  TRP n 
1 98  GLY n 
1 99  ARG n 
1 100 SER n 
1 101 GLU n 
1 102 ARG n 
1 103 THR n 
1 104 LEU n 
1 105 ASP n 
1 106 SER n 
1 107 LEU n 
1 108 ASP n 
1 109 GLU n 
1 110 PRO n 
1 111 PRO n 
1 112 ALA n 
1 113 TRP n 
1 114 PHE n 
1 115 ARG n 
1 116 ARG n 
1 117 GLU n 
1 118 MET n 
1 119 GLY n 
1 120 GLU n 
1 121 TRP n 
1 122 LYS n 
1 123 LYS n 
1 124 ALA n 
1 125 ARG n 
1 126 GLU n 
1 127 GLU n 
1 128 ASP n 
1 129 LYS n 
1 130 GLU n 
1 131 TRP n 
1 132 ARG n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 ASP n 
1 137 GLU n 
1 138 ARG n 
1 139 LEU n 
1 140 GLU n 
1 141 ASN n 
1 142 LEU n 
1 143 LEU n 
1 144 ASN n 
1 145 ILE n 
1 146 VAL n 
1 147 ARG n 
1 148 GLU n 
1 149 ILE n 
1 150 LEU n 
1 151 ASP n 
1 152 VAL n 
1 153 GLN n 
1 154 ARG n 
1 155 ASP n 
1 156 MET n 
1 157 ARG n 
1 158 ASN n 
1 159 ASP n 
1 160 LEU n 
1 161 SER n 
1 162 ASN n 
1 163 LEU n 
1 164 THR n 
1 165 ARG n 
1 166 LYS n 
1 167 VAL n 
1 168 ASP n 
1 169 ARG n 
1 170 MET n 
1 171 ASP n 
1 172 MET n 
1 173 ARG n 
1 174 LEU n 
1 175 SER n 
1 176 ARG n 
1 177 ASN n 
1 178 ASN n 
1 179 ASN n 
1 180 MET n 
1 181 ILE n 
1 182 MET n 
1 183 ARG n 
1 184 SER n 
1 185 PHE n 
1 186 ARG n 
1 187 GLN n 
1 188 PRO n 
1 189 ILE n 
1 190 THR n 
1 191 GLU n 
1 192 VAL n 
1 193 PRO n 
1 194 PHE n 
1 195 PHE n 
1 196 ASN n 
1 197 GLY n 
1 198 ASP n 
1 199 ILE n 
1 200 PRO n 
1 201 ASP n 
1 202 PRO n 
1 203 ASN n 
1 204 LEU n 
1 205 PRO n 
1 206 ARG n 
1 207 ILE n 
1 208 THR n 
1 209 ARG n 
1 210 ILE n 
1 211 GLU n 
1 212 ASP n 
1 213 ILE n 
1 214 ASP n 
1 215 SER n 
1 216 LEU n 
1 217 SER n 
1 218 GLU n 
1 219 GLU n 
1 220 ASN n 
1 221 CYS n 
1 222 THR n 
1 223 ARG n 
1 224 TYR n 
1 225 LEU n 
1 226 LYS n 
1 227 GLY n 
1 228 TYR n 
1 229 GLY n 
1 230 VAL n 
1 231 SER n 
1 232 TYR n 
1 233 ASP n 
1 234 GLU n 
1 235 ASN n 
1 236 ASP n 
1 237 GLN n 
1 238 SER n 
1 239 LEU n 
1 240 TRP n 
1 241 LYS n 
1 242 ARG n 
1 243 GLN n 
1 244 LEU n 
1 245 ALA n 
1 246 LYS n 
1 247 ALA n 
1 248 VAL n 
1 249 GLY n 
1 250 LEU n 
1 251 THR n 
1 252 ALA n 
1 253 ALA n 
1 254 TYR n 
1 255 ASP n 
1 256 ALA n 
1 257 SER n 
1 258 TYR n 
1 259 THR n 
1 260 PHE n 
1 261 SER n 
1 262 PRO n 
1 263 PHE n 
1 264 SER n 
1 265 SER n 
1 266 SER n 
1 267 GLU n 
1 268 SER n 
1 269 GLY n 
1 270 GLY n 
1 271 GLY n 
1 272 SER n 
1 273 SER n 
1 274 GLY n 
1 275 GLY n 
1 276 GLY n 
1 277 SER n 
1 278 THR n 
1 279 TYR n 
1 280 LYS n 
1 281 LEU n 
1 282 ILE n 
1 283 LEU n 
1 284 ASN n 
1 285 GLY n 
1 286 LYS n 
1 287 THR n 
1 288 LEU n 
1 289 LYS n 
1 290 GLY n 
1 291 GLU n 
1 292 THR n 
1 293 THR n 
1 294 THR n 
1 295 GLU n 
1 296 ALA n 
1 297 VAL n 
1 298 ASP n 
1 299 ALA n 
1 300 ALA n 
1 301 THR n 
1 302 ALA n 
1 303 GLU n 
1 304 LYS n 
1 305 VAL n 
1 306 PHE n 
1 307 LYS n 
1 308 GLN n 
1 309 TYR n 
1 310 ALA n 
1 311 ASN n 
1 312 ASP n 
1 313 ASN n 
1 314 GLY n 
1 315 VAL n 
1 316 ASP n 
1 317 GLY n 
1 318 GLU n 
1 319 TRP n 
1 320 THR n 
1 321 TYR n 
1 322 ASP n 
1 323 ASP n 
1 324 ALA n 
1 325 THR n 
1 326 LYS n 
1 327 THR n 
1 328 PHE n 
1 329 THR n 
1 330 VAL n 
1 331 THR n 
1 332 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   129 'Fission yeast' ? 'mug135, SPCC330.04c' ? ? ? ? ? ? 'Schizosaccharomyces pombe 972h-' 
284812 ? ? ? ? ? ? ? ? 'Schizosaccharomyces pombe 972h-' 284812 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 130 267 'Fission yeast' ? 'mug135, SPCC330.04c' ? ? ? ? ? ? 'Schizosaccharomyces pombe 972h-' 
284812 ? ? ? ? ? ? ? ? 'Schizosaccharomyces pombe 972h-' 284812 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 268 332 ?               ? spg                   ? ? ? ? ? ? 'Streptococcus sp. group G'       
1320   ? ? ? ? ? ? ? ? 'Schizosaccharomyces pombe 972h-' 284812 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   91  ?   ?   ?   A . n 
A 1 2   SER 2   92  ?   ?   ?   A . n 
A 1 3   GLU 3   93  ?   ?   ?   A . n 
A 1 4   GLU 4   94  ?   ?   ?   A . n 
A 1 5   ASP 5   95  ?   ?   ?   A . n 
A 1 6   ASN 6   96  ?   ?   ?   A . n 
A 1 7   ARG 7   97  ?   ?   ?   A . n 
A 1 8   LEU 8   98  ?   ?   ?   A . n 
A 1 9   ASN 9   99  ?   ?   ?   A . n 
A 1 10  GLU 10  100 ?   ?   ?   A . n 
A 1 11  LEU 11  101 ?   ?   ?   A . n 
A 1 12  PHE 12  102 ?   ?   ?   A . n 
A 1 13  ALA 13  103 ?   ?   ?   A . n 
A 1 14  ASN 14  104 ?   ?   ?   A . n 
A 1 15  ASP 15  105 ?   ?   ?   A . n 
A 1 16  LEU 16  106 ?   ?   ?   A . n 
A 1 17  GLY 17  107 ?   ?   ?   A . n 
A 1 18  VAL 18  108 ?   ?   ?   A . n 
A 1 19  GLN 19  109 ?   ?   ?   A . n 
A 1 20  PRO 20  110 ?   ?   ?   A . n 
A 1 21  PRO 21  111 ?   ?   ?   A . n 
A 1 22  CYS 22  112 ?   ?   ?   A . n 
A 1 23  GLU 23  113 ?   ?   ?   A . n 
A 1 24  ARG 24  114 ?   ?   ?   A . n 
A 1 25  SER 25  115 ?   ?   ?   A . n 
A 1 26  LEU 26  116 ?   ?   ?   A . n 
A 1 27  LYS 27  117 ?   ?   ?   A . n 
A 1 28  GLU 28  118 ?   ?   ?   A . n 
A 1 29  GLY 29  119 ?   ?   ?   A . n 
A 1 30  ARG 30  120 ?   ?   ?   A . n 
A 1 31  ARG 31  121 ?   ?   ?   A . n 
A 1 32  PHE 32  122 ?   ?   ?   A . n 
A 1 33  LEU 33  123 ?   ?   ?   A . n 
A 1 34  ASN 34  124 ?   ?   ?   A . n 
A 1 35  ASP 35  125 ?   ?   ?   A . n 
A 1 36  PHE 36  126 ?   ?   ?   A . n 
A 1 37  GLU 37  127 ?   ?   ?   A . n 
A 1 38  ILE 38  128 ?   ?   ?   A . n 
A 1 39  ALA 39  129 ?   ?   ?   A . n 
A 1 40  ALA 40  130 ?   ?   ?   A . n 
A 1 41  LYS 41  131 ?   ?   ?   A . n 
A 1 42  LYS 42  132 ?   ?   ?   A . n 
A 1 43  LYS 43  133 ?   ?   ?   A . n 
A 1 44  LEU 44  134 ?   ?   ?   A . n 
A 1 45  LEU 45  135 ?   ?   ?   A . n 
A 1 46  GLU 46  136 ?   ?   ?   A . n 
A 1 47  LEU 47  137 ?   ?   ?   A . n 
A 1 48  GLU 48  138 ?   ?   ?   A . n 
A 1 49  ARG 49  139 ?   ?   ?   A . n 
A 1 50  LYS 50  140 ?   ?   ?   A . n 
A 1 51  ALA 51  141 ?   ?   ?   A . n 
A 1 52  LEU 52  142 ?   ?   ?   A . n 
A 1 53  GLU 53  143 ?   ?   ?   A . n 
A 1 54  ASP 54  144 ?   ?   ?   A . n 
A 1 55  LYS 55  145 ?   ?   ?   A . n 
A 1 56  GLU 56  146 ?   ?   ?   A . n 
A 1 57  LYS 57  147 ?   ?   ?   A . n 
A 1 58  ASN 58  148 ?   ?   ?   A . n 
A 1 59  LEU 59  149 ?   ?   ?   A . n 
A 1 60  ASN 60  150 ?   ?   ?   A . n 
A 1 61  PHE 61  151 ?   ?   ?   A . n 
A 1 62  VAL 62  152 ?   ?   ?   A . n 
A 1 63  VAL 63  153 ?   ?   ?   A . n 
A 1 64  GLU 64  154 ?   ?   ?   A . n 
A 1 65  SER 65  155 ?   ?   ?   A . n 
A 1 66  GLU 66  156 ?   ?   ?   A . n 
A 1 67  ARG 67  157 ?   ?   ?   A . n 
A 1 68  THR 68  158 ?   ?   ?   A . n 
A 1 69  LEU 69  159 ?   ?   ?   A . n 
A 1 70  PHE 70  160 ?   ?   ?   A . n 
A 1 71  ASN 71  161 ?   ?   ?   A . n 
A 1 72  SER 72  162 ?   ?   ?   A . n 
A 1 73  LYS 73  163 ?   ?   ?   A . n 
A 1 74  LYS 74  164 ?   ?   ?   A . n 
A 1 75  ARG 75  165 ?   ?   ?   A . n 
A 1 76  ALA 76  166 ?   ?   ?   A . n 
A 1 77  PHE 77  167 ?   ?   ?   A . n 
A 1 78  ASP 78  168 ?   ?   ?   A . n 
A 1 79  ASN 79  169 ?   ?   ?   A . n 
A 1 80  ASP 80  170 ?   ?   ?   A . n 
A 1 81  GLU 81  171 ?   ?   ?   A . n 
A 1 82  CYS 82  172 ?   ?   ?   A . n 
A 1 83  TYR 83  173 ?   ?   ?   A . n 
A 1 84  ASN 84  174 ?   ?   ?   A . n 
A 1 85  ASP 85  175 ?   ?   ?   A . n 
A 1 86  ARG 86  176 ?   ?   ?   A . n 
A 1 87  CYS 87  177 ?   ?   ?   A . n 
A 1 88  LYS 88  178 ?   ?   ?   A . n 
A 1 89  LEU 89  179 ?   ?   ?   A . n 
A 1 90  PHE 90  180 ?   ?   ?   A . n 
A 1 91  ARG 91  181 ?   ?   ?   A . n 
A 1 92  GLY 92  182 ?   ?   ?   A . n 
A 1 93  ILE 93  183 ?   ?   ?   A . n 
A 1 94  VAL 94  184 ?   ?   ?   A . n 
A 1 95  ASN 95  185 ?   ?   ?   A . n 
A 1 96  GLU 96  186 ?   ?   ?   A . n 
A 1 97  TRP 97  187 ?   ?   ?   A . n 
A 1 98  GLY 98  188 ?   ?   ?   A . n 
A 1 99  ARG 99  189 ?   ?   ?   A . n 
A 1 100 SER 100 190 ?   ?   ?   A . n 
A 1 101 GLU 101 191 ?   ?   ?   A . n 
A 1 102 ARG 102 192 ?   ?   ?   A . n 
A 1 103 THR 103 193 ?   ?   ?   A . n 
A 1 104 LEU 104 194 ?   ?   ?   A . n 
A 1 105 ASP 105 195 ?   ?   ?   A . n 
A 1 106 SER 106 196 ?   ?   ?   A . n 
A 1 107 LEU 107 197 ?   ?   ?   A . n 
A 1 108 ASP 108 198 ?   ?   ?   A . n 
A 1 109 GLU 109 199 ?   ?   ?   A . n 
A 1 110 PRO 110 200 ?   ?   ?   A . n 
A 1 111 PRO 111 201 ?   ?   ?   A . n 
A 1 112 ALA 112 202 ?   ?   ?   A . n 
A 1 113 TRP 113 203 ?   ?   ?   A . n 
A 1 114 PHE 114 204 ?   ?   ?   A . n 
A 1 115 ARG 115 205 ?   ?   ?   A . n 
A 1 116 ARG 116 206 ?   ?   ?   A . n 
A 1 117 GLU 117 207 ?   ?   ?   A . n 
A 1 118 MET 118 208 208 MET MET A . n 
A 1 119 GLY 119 209 209 GLY GLY A . n 
A 1 120 GLU 120 210 210 GLU GLU A . n 
A 1 121 TRP 121 211 211 TRP TRP A . n 
A 1 122 LYS 122 212 212 LYS LYS A . n 
A 1 123 LYS 123 213 213 LYS LYS A . n 
A 1 124 ALA 124 214 214 ALA ALA A . n 
A 1 125 ARG 125 215 215 ARG ARG A . n 
A 1 126 GLU 126 216 216 GLU GLU A . n 
A 1 127 GLU 127 217 217 GLU GLU A . n 
A 1 128 ASP 128 218 218 ASP ASP A . n 
A 1 129 LYS 129 219 219 LYS LYS A . n 
A 1 130 GLU 130 220 220 GLU GLU A . n 
A 1 131 TRP 131 221 221 TRP TRP A . n 
A 1 132 ARG 132 222 222 ARG ARG A . n 
A 1 133 LYS 133 223 223 LYS LYS A . n 
A 1 134 SER 134 224 224 SER SER A . n 
A 1 135 THR 135 225 225 THR THR A . n 
A 1 136 ASP 136 226 226 ASP ASP A . n 
A 1 137 GLU 137 227 227 GLU GLU A . n 
A 1 138 ARG 138 228 228 ARG ARG A . n 
A 1 139 LEU 139 229 229 LEU LEU A . n 
A 1 140 GLU 140 230 230 GLU GLU A . n 
A 1 141 ASN 141 231 231 ASN ASN A . n 
A 1 142 LEU 142 232 232 LEU LEU A . n 
A 1 143 LEU 143 233 233 LEU LEU A . n 
A 1 144 ASN 144 234 234 ASN ASN A . n 
A 1 145 ILE 145 235 235 ILE ILE A . n 
A 1 146 VAL 146 236 236 VAL VAL A . n 
A 1 147 ARG 147 237 237 ARG ARG A . n 
A 1 148 GLU 148 238 238 GLU GLU A . n 
A 1 149 ILE 149 239 239 ILE ILE A . n 
A 1 150 LEU 150 240 240 LEU LEU A . n 
A 1 151 ASP 151 241 241 ASP ASP A . n 
A 1 152 VAL 152 242 242 VAL VAL A . n 
A 1 153 GLN 153 243 243 GLN GLN A . n 
A 1 154 ARG 154 244 244 ARG ARG A . n 
A 1 155 ASP 155 245 245 ASP ASP A . n 
A 1 156 MET 156 246 246 MET MET A . n 
A 1 157 ARG 157 247 247 ARG ARG A . n 
A 1 158 ASN 158 248 248 ASN ASN A . n 
A 1 159 ASP 159 249 249 ASP ASP A . n 
A 1 160 LEU 160 250 250 LEU LEU A . n 
A 1 161 SER 161 251 251 SER SER A . n 
A 1 162 ASN 162 252 252 ASN ASN A . n 
A 1 163 LEU 163 253 253 LEU LEU A . n 
A 1 164 THR 164 254 254 THR THR A . n 
A 1 165 ARG 165 255 255 ARG ARG A . n 
A 1 166 LYS 166 256 256 LYS LYS A . n 
A 1 167 VAL 167 257 257 VAL VAL A . n 
A 1 168 ASP 168 258 258 ASP ASP A . n 
A 1 169 ARG 169 259 259 ARG ARG A . n 
A 1 170 MET 170 260 260 MET MET A . n 
A 1 171 ASP 171 261 261 ASP ASP A . n 
A 1 172 MET 172 262 262 MET MET A . n 
A 1 173 ARG 173 263 263 ARG ARG A . n 
A 1 174 LEU 174 264 264 LEU LEU A . n 
A 1 175 SER 175 265 265 SER SER A . n 
A 1 176 ARG 176 266 266 ARG ARG A . n 
A 1 177 ASN 177 267 267 ASN ASN A . n 
A 1 178 ASN 178 268 268 ASN ASN A . n 
A 1 179 ASN 179 269 269 ASN ASN A . n 
A 1 180 MET 180 270 270 MET MET A . n 
A 1 181 ILE 181 271 271 ILE ILE A . n 
A 1 182 MET 182 272 272 MET MET A . n 
A 1 183 ARG 183 273 273 ARG ARG A . n 
A 1 184 SER 184 274 274 SER SER A . n 
A 1 185 PHE 185 275 275 PHE PHE A . n 
A 1 186 ARG 186 276 276 ARG ARG A . n 
A 1 187 GLN 187 277 277 GLN GLN A . n 
A 1 188 PRO 188 278 278 PRO PRO A . n 
A 1 189 ILE 189 279 279 ILE ILE A . n 
A 1 190 THR 190 280 280 THR THR A . n 
A 1 191 GLU 191 281 281 GLU GLU A . n 
A 1 192 VAL 192 282 282 VAL VAL A . n 
A 1 193 PRO 193 283 283 PRO PRO A . n 
A 1 194 PHE 194 284 284 PHE PHE A . n 
A 1 195 PHE 195 285 285 PHE PHE A . n 
A 1 196 ASN 196 286 286 ASN ASN A . n 
A 1 197 GLY 197 287 287 GLY GLY A . n 
A 1 198 ASP 198 288 288 ASP ASP A . n 
A 1 199 ILE 199 289 289 ILE ILE A . n 
A 1 200 PRO 200 290 290 PRO PRO A . n 
A 1 201 ASP 201 291 291 ASP ASP A . n 
A 1 202 PRO 202 292 292 PRO PRO A . n 
A 1 203 ASN 203 293 293 ASN ASN A . n 
A 1 204 LEU 204 294 294 LEU LEU A . n 
A 1 205 PRO 205 295 295 PRO PRO A . n 
A 1 206 ARG 206 296 296 ARG ARG A . n 
A 1 207 ILE 207 297 297 ILE ILE A . n 
A 1 208 THR 208 298 298 THR THR A . n 
A 1 209 ARG 209 299 299 ARG ARG A . n 
A 1 210 ILE 210 300 300 ILE ILE A . n 
A 1 211 GLU 211 301 301 GLU GLU A . n 
A 1 212 ASP 212 302 302 ASP ASP A . n 
A 1 213 ILE 213 303 303 ILE ILE A . n 
A 1 214 ASP 214 304 304 ASP ASP A . n 
A 1 215 SER 215 305 305 SER SER A . n 
A 1 216 LEU 216 306 306 LEU LEU A . n 
A 1 217 SER 217 307 307 SER SER A . n 
A 1 218 GLU 218 308 308 GLU GLU A . n 
A 1 219 GLU 219 309 309 GLU GLU A . n 
A 1 220 ASN 220 310 310 ASN ASN A . n 
A 1 221 CYS 221 311 311 CYS CYS A . n 
A 1 222 THR 222 312 312 THR THR A . n 
A 1 223 ARG 223 313 313 ARG ARG A . n 
A 1 224 TYR 224 314 314 TYR TYR A . n 
A 1 225 LEU 225 315 315 LEU LEU A . n 
A 1 226 LYS 226 316 316 LYS LYS A . n 
A 1 227 GLY 227 317 317 GLY GLY A . n 
A 1 228 TYR 228 318 318 TYR TYR A . n 
A 1 229 GLY 229 319 319 GLY GLY A . n 
A 1 230 VAL 230 320 320 VAL VAL A . n 
A 1 231 SER 231 321 321 SER SER A . n 
A 1 232 TYR 232 322 322 TYR TYR A . n 
A 1 233 ASP 233 323 323 ASP ASP A . n 
A 1 234 GLU 234 324 324 GLU GLU A . n 
A 1 235 ASN 235 325 325 ASN ASN A . n 
A 1 236 ASP 236 326 326 ASP ASP A . n 
A 1 237 GLN 237 327 327 GLN GLN A . n 
A 1 238 SER 238 328 328 SER SER A . n 
A 1 239 LEU 239 329 329 LEU LEU A . n 
A 1 240 TRP 240 330 330 TRP TRP A . n 
A 1 241 LYS 241 331 331 LYS LYS A . n 
A 1 242 ARG 242 332 332 ARG ARG A . n 
A 1 243 GLN 243 333 333 GLN GLN A . n 
A 1 244 LEU 244 334 334 LEU LEU A . n 
A 1 245 ALA 245 335 335 ALA ALA A . n 
A 1 246 LYS 246 336 336 LYS LYS A . n 
A 1 247 ALA 247 337 337 ALA ALA A . n 
A 1 248 VAL 248 338 338 VAL VAL A . n 
A 1 249 GLY 249 339 339 GLY GLY A . n 
A 1 250 LEU 250 340 340 LEU LEU A . n 
A 1 251 THR 251 341 341 THR THR A . n 
A 1 252 ALA 252 342 342 ALA ALA A . n 
A 1 253 ALA 253 343 343 ALA ALA A . n 
A 1 254 TYR 254 344 344 TYR TYR A . n 
A 1 255 ASP 255 345 345 ASP ASP A . n 
A 1 256 ALA 256 346 346 ALA ALA A . n 
A 1 257 SER 257 347 347 SER SER A . n 
A 1 258 TYR 258 348 348 TYR TYR A . n 
A 1 259 THR 259 349 349 THR THR A . n 
A 1 260 PHE 260 350 350 PHE PHE A . n 
A 1 261 SER 261 351 351 SER SER A . n 
A 1 262 PRO 262 352 352 PRO PRO A . n 
A 1 263 PHE 263 353 353 PHE PHE A . n 
A 1 264 SER 264 354 354 SER SER A . n 
A 1 265 SER 265 355 ?   ?   ?   A . n 
A 1 266 SER 266 356 ?   ?   ?   A . n 
A 1 267 GLU 267 357 ?   ?   ?   A . n 
A 1 268 SER 268 358 ?   ?   ?   A . n 
A 1 269 GLY 269 359 ?   ?   ?   A . n 
A 1 270 GLY 270 360 ?   ?   ?   A . n 
A 1 271 GLY 271 361 ?   ?   ?   A . n 
A 1 272 SER 272 362 ?   ?   ?   A . n 
A 1 273 SER 273 363 ?   ?   ?   A . n 
A 1 274 GLY 274 364 ?   ?   ?   A . n 
A 1 275 GLY 275 365 ?   ?   ?   A . n 
A 1 276 GLY 276 366 ?   ?   ?   A . n 
A 1 277 SER 277 367 ?   ?   ?   A . n 
A 1 278 THR 278 368 ?   ?   ?   A . n 
A 1 279 TYR 279 369 ?   ?   ?   A . n 
A 1 280 LYS 280 370 ?   ?   ?   A . n 
A 1 281 LEU 281 371 ?   ?   ?   A . n 
A 1 282 ILE 282 372 ?   ?   ?   A . n 
A 1 283 LEU 283 373 ?   ?   ?   A . n 
A 1 284 ASN 284 374 ?   ?   ?   A . n 
A 1 285 GLY 285 375 ?   ?   ?   A . n 
A 1 286 LYS 286 376 ?   ?   ?   A . n 
A 1 287 THR 287 377 ?   ?   ?   A . n 
A 1 288 LEU 288 378 ?   ?   ?   A . n 
A 1 289 LYS 289 379 ?   ?   ?   A . n 
A 1 290 GLY 290 380 ?   ?   ?   A . n 
A 1 291 GLU 291 381 ?   ?   ?   A . n 
A 1 292 THR 292 382 ?   ?   ?   A . n 
A 1 293 THR 293 383 ?   ?   ?   A . n 
A 1 294 THR 294 384 ?   ?   ?   A . n 
A 1 295 GLU 295 385 ?   ?   ?   A . n 
A 1 296 ALA 296 386 ?   ?   ?   A . n 
A 1 297 VAL 297 387 ?   ?   ?   A . n 
A 1 298 ASP 298 388 ?   ?   ?   A . n 
A 1 299 ALA 299 389 ?   ?   ?   A . n 
A 1 300 ALA 300 390 ?   ?   ?   A . n 
A 1 301 THR 301 391 ?   ?   ?   A . n 
A 1 302 ALA 302 392 ?   ?   ?   A . n 
A 1 303 GLU 303 393 ?   ?   ?   A . n 
A 1 304 LYS 304 394 ?   ?   ?   A . n 
A 1 305 VAL 305 395 ?   ?   ?   A . n 
A 1 306 PHE 306 396 ?   ?   ?   A . n 
A 1 307 LYS 307 397 ?   ?   ?   A . n 
A 1 308 GLN 308 398 ?   ?   ?   A . n 
A 1 309 TYR 309 399 ?   ?   ?   A . n 
A 1 310 ALA 310 400 ?   ?   ?   A . n 
A 1 311 ASN 311 401 ?   ?   ?   A . n 
A 1 312 ASP 312 402 ?   ?   ?   A . n 
A 1 313 ASN 313 403 ?   ?   ?   A . n 
A 1 314 GLY 314 404 ?   ?   ?   A . n 
A 1 315 VAL 315 405 ?   ?   ?   A . n 
A 1 316 ASP 316 406 ?   ?   ?   A . n 
A 1 317 GLY 317 407 ?   ?   ?   A . n 
A 1 318 GLU 318 408 ?   ?   ?   A . n 
A 1 319 TRP 319 409 ?   ?   ?   A . n 
A 1 320 THR 320 410 ?   ?   ?   A . n 
A 1 321 TYR 321 411 ?   ?   ?   A . n 
A 1 322 ASP 322 412 ?   ?   ?   A . n 
A 1 323 ASP 323 413 ?   ?   ?   A . n 
A 1 324 ALA 324 414 ?   ?   ?   A . n 
A 1 325 THR 325 415 ?   ?   ?   A . n 
A 1 326 LYS 326 416 ?   ?   ?   A . n 
A 1 327 THR 327 417 ?   ?   ?   A . n 
A 1 328 PHE 328 418 ?   ?   ?   A . n 
A 1 329 THR 329 419 ?   ?   ?   A . n 
A 1 330 VAL 330 420 ?   ?   ?   A . n 
A 1 331 THR 331 421 ?   ?   ?   A . n 
A 1 332 GLU 332 422 ?   ?   ?   A . n 
B 1 1   MET 1   91  ?   ?   ?   B . n 
B 1 2   SER 2   92  ?   ?   ?   B . n 
B 1 3   GLU 3   93  ?   ?   ?   B . n 
B 1 4   GLU 4   94  ?   ?   ?   B . n 
B 1 5   ASP 5   95  ?   ?   ?   B . n 
B 1 6   ASN 6   96  ?   ?   ?   B . n 
B 1 7   ARG 7   97  ?   ?   ?   B . n 
B 1 8   LEU 8   98  ?   ?   ?   B . n 
B 1 9   ASN 9   99  ?   ?   ?   B . n 
B 1 10  GLU 10  100 ?   ?   ?   B . n 
B 1 11  LEU 11  101 ?   ?   ?   B . n 
B 1 12  PHE 12  102 ?   ?   ?   B . n 
B 1 13  ALA 13  103 ?   ?   ?   B . n 
B 1 14  ASN 14  104 ?   ?   ?   B . n 
B 1 15  ASP 15  105 ?   ?   ?   B . n 
B 1 16  LEU 16  106 ?   ?   ?   B . n 
B 1 17  GLY 17  107 ?   ?   ?   B . n 
B 1 18  VAL 18  108 ?   ?   ?   B . n 
B 1 19  GLN 19  109 ?   ?   ?   B . n 
B 1 20  PRO 20  110 ?   ?   ?   B . n 
B 1 21  PRO 21  111 ?   ?   ?   B . n 
B 1 22  CYS 22  112 ?   ?   ?   B . n 
B 1 23  GLU 23  113 ?   ?   ?   B . n 
B 1 24  ARG 24  114 ?   ?   ?   B . n 
B 1 25  SER 25  115 ?   ?   ?   B . n 
B 1 26  LEU 26  116 ?   ?   ?   B . n 
B 1 27  LYS 27  117 ?   ?   ?   B . n 
B 1 28  GLU 28  118 ?   ?   ?   B . n 
B 1 29  GLY 29  119 ?   ?   ?   B . n 
B 1 30  ARG 30  120 ?   ?   ?   B . n 
B 1 31  ARG 31  121 ?   ?   ?   B . n 
B 1 32  PHE 32  122 ?   ?   ?   B . n 
B 1 33  LEU 33  123 ?   ?   ?   B . n 
B 1 34  ASN 34  124 ?   ?   ?   B . n 
B 1 35  ASP 35  125 ?   ?   ?   B . n 
B 1 36  PHE 36  126 ?   ?   ?   B . n 
B 1 37  GLU 37  127 ?   ?   ?   B . n 
B 1 38  ILE 38  128 ?   ?   ?   B . n 
B 1 39  ALA 39  129 ?   ?   ?   B . n 
B 1 40  ALA 40  130 ?   ?   ?   B . n 
B 1 41  LYS 41  131 ?   ?   ?   B . n 
B 1 42  LYS 42  132 ?   ?   ?   B . n 
B 1 43  LYS 43  133 ?   ?   ?   B . n 
B 1 44  LEU 44  134 ?   ?   ?   B . n 
B 1 45  LEU 45  135 ?   ?   ?   B . n 
B 1 46  GLU 46  136 ?   ?   ?   B . n 
B 1 47  LEU 47  137 ?   ?   ?   B . n 
B 1 48  GLU 48  138 ?   ?   ?   B . n 
B 1 49  ARG 49  139 ?   ?   ?   B . n 
B 1 50  LYS 50  140 ?   ?   ?   B . n 
B 1 51  ALA 51  141 ?   ?   ?   B . n 
B 1 52  LEU 52  142 ?   ?   ?   B . n 
B 1 53  GLU 53  143 ?   ?   ?   B . n 
B 1 54  ASP 54  144 ?   ?   ?   B . n 
B 1 55  LYS 55  145 ?   ?   ?   B . n 
B 1 56  GLU 56  146 ?   ?   ?   B . n 
B 1 57  LYS 57  147 ?   ?   ?   B . n 
B 1 58  ASN 58  148 ?   ?   ?   B . n 
B 1 59  LEU 59  149 ?   ?   ?   B . n 
B 1 60  ASN 60  150 ?   ?   ?   B . n 
B 1 61  PHE 61  151 ?   ?   ?   B . n 
B 1 62  VAL 62  152 ?   ?   ?   B . n 
B 1 63  VAL 63  153 ?   ?   ?   B . n 
B 1 64  GLU 64  154 ?   ?   ?   B . n 
B 1 65  SER 65  155 ?   ?   ?   B . n 
B 1 66  GLU 66  156 ?   ?   ?   B . n 
B 1 67  ARG 67  157 ?   ?   ?   B . n 
B 1 68  THR 68  158 ?   ?   ?   B . n 
B 1 69  LEU 69  159 ?   ?   ?   B . n 
B 1 70  PHE 70  160 ?   ?   ?   B . n 
B 1 71  ASN 71  161 ?   ?   ?   B . n 
B 1 72  SER 72  162 ?   ?   ?   B . n 
B 1 73  LYS 73  163 ?   ?   ?   B . n 
B 1 74  LYS 74  164 ?   ?   ?   B . n 
B 1 75  ARG 75  165 ?   ?   ?   B . n 
B 1 76  ALA 76  166 ?   ?   ?   B . n 
B 1 77  PHE 77  167 ?   ?   ?   B . n 
B 1 78  ASP 78  168 ?   ?   ?   B . n 
B 1 79  ASN 79  169 ?   ?   ?   B . n 
B 1 80  ASP 80  170 ?   ?   ?   B . n 
B 1 81  GLU 81  171 ?   ?   ?   B . n 
B 1 82  CYS 82  172 ?   ?   ?   B . n 
B 1 83  TYR 83  173 ?   ?   ?   B . n 
B 1 84  ASN 84  174 ?   ?   ?   B . n 
B 1 85  ASP 85  175 ?   ?   ?   B . n 
B 1 86  ARG 86  176 ?   ?   ?   B . n 
B 1 87  CYS 87  177 ?   ?   ?   B . n 
B 1 88  LYS 88  178 ?   ?   ?   B . n 
B 1 89  LEU 89  179 ?   ?   ?   B . n 
B 1 90  PHE 90  180 ?   ?   ?   B . n 
B 1 91  ARG 91  181 ?   ?   ?   B . n 
B 1 92  GLY 92  182 ?   ?   ?   B . n 
B 1 93  ILE 93  183 ?   ?   ?   B . n 
B 1 94  VAL 94  184 ?   ?   ?   B . n 
B 1 95  ASN 95  185 ?   ?   ?   B . n 
B 1 96  GLU 96  186 ?   ?   ?   B . n 
B 1 97  TRP 97  187 ?   ?   ?   B . n 
B 1 98  GLY 98  188 ?   ?   ?   B . n 
B 1 99  ARG 99  189 ?   ?   ?   B . n 
B 1 100 SER 100 190 ?   ?   ?   B . n 
B 1 101 GLU 101 191 ?   ?   ?   B . n 
B 1 102 ARG 102 192 ?   ?   ?   B . n 
B 1 103 THR 103 193 ?   ?   ?   B . n 
B 1 104 LEU 104 194 ?   ?   ?   B . n 
B 1 105 ASP 105 195 ?   ?   ?   B . n 
B 1 106 SER 106 196 ?   ?   ?   B . n 
B 1 107 LEU 107 197 ?   ?   ?   B . n 
B 1 108 ASP 108 198 ?   ?   ?   B . n 
B 1 109 GLU 109 199 ?   ?   ?   B . n 
B 1 110 PRO 110 200 ?   ?   ?   B . n 
B 1 111 PRO 111 201 ?   ?   ?   B . n 
B 1 112 ALA 112 202 ?   ?   ?   B . n 
B 1 113 TRP 113 203 ?   ?   ?   B . n 
B 1 114 PHE 114 204 ?   ?   ?   B . n 
B 1 115 ARG 115 205 ?   ?   ?   B . n 
B 1 116 ARG 116 206 ?   ?   ?   B . n 
B 1 117 GLU 117 207 ?   ?   ?   B . n 
B 1 118 MET 118 208 208 MET MET B . n 
B 1 119 GLY 119 209 209 GLY GLY B . n 
B 1 120 GLU 120 210 210 GLU GLU B . n 
B 1 121 TRP 121 211 211 TRP TRP B . n 
B 1 122 LYS 122 212 212 LYS LYS B . n 
B 1 123 LYS 123 213 213 LYS LYS B . n 
B 1 124 ALA 124 214 214 ALA ALA B . n 
B 1 125 ARG 125 215 215 ARG ARG B . n 
B 1 126 GLU 126 216 216 GLU GLU B . n 
B 1 127 GLU 127 217 217 GLU GLU B . n 
B 1 128 ASP 128 218 218 ASP ASP B . n 
B 1 129 LYS 129 219 219 LYS LYS B . n 
B 1 130 GLU 130 220 220 GLU GLU B . n 
B 1 131 TRP 131 221 221 TRP TRP B . n 
B 1 132 ARG 132 222 222 ARG ARG B . n 
B 1 133 LYS 133 223 223 LYS LYS B . n 
B 1 134 SER 134 224 224 SER SER B . n 
B 1 135 THR 135 225 225 THR THR B . n 
B 1 136 ASP 136 226 226 ASP ASP B . n 
B 1 137 GLU 137 227 227 GLU GLU B . n 
B 1 138 ARG 138 228 228 ARG ARG B . n 
B 1 139 LEU 139 229 229 LEU LEU B . n 
B 1 140 GLU 140 230 230 GLU GLU B . n 
B 1 141 ASN 141 231 231 ASN ASN B . n 
B 1 142 LEU 142 232 232 LEU LEU B . n 
B 1 143 LEU 143 233 233 LEU LEU B . n 
B 1 144 ASN 144 234 234 ASN ASN B . n 
B 1 145 ILE 145 235 235 ILE ILE B . n 
B 1 146 VAL 146 236 236 VAL VAL B . n 
B 1 147 ARG 147 237 237 ARG ARG B . n 
B 1 148 GLU 148 238 238 GLU GLU B . n 
B 1 149 ILE 149 239 239 ILE ILE B . n 
B 1 150 LEU 150 240 240 LEU LEU B . n 
B 1 151 ASP 151 241 241 ASP ASP B . n 
B 1 152 VAL 152 242 242 VAL VAL B . n 
B 1 153 GLN 153 243 243 GLN GLN B . n 
B 1 154 ARG 154 244 244 ARG ARG B . n 
B 1 155 ASP 155 245 245 ASP ASP B . n 
B 1 156 MET 156 246 246 MET MET B . n 
B 1 157 ARG 157 247 247 ARG ARG B . n 
B 1 158 ASN 158 248 248 ASN ASN B . n 
B 1 159 ASP 159 249 249 ASP ASP B . n 
B 1 160 LEU 160 250 250 LEU LEU B . n 
B 1 161 SER 161 251 251 SER SER B . n 
B 1 162 ASN 162 252 252 ASN ASN B . n 
B 1 163 LEU 163 253 253 LEU LEU B . n 
B 1 164 THR 164 254 254 THR THR B . n 
B 1 165 ARG 165 255 255 ARG ARG B . n 
B 1 166 LYS 166 256 256 LYS LYS B . n 
B 1 167 VAL 167 257 257 VAL VAL B . n 
B 1 168 ASP 168 258 258 ASP ASP B . n 
B 1 169 ARG 169 259 259 ARG ARG B . n 
B 1 170 MET 170 260 260 MET MET B . n 
B 1 171 ASP 171 261 261 ASP ASP B . n 
B 1 172 MET 172 262 262 MET MET B . n 
B 1 173 ARG 173 263 263 ARG ARG B . n 
B 1 174 LEU 174 264 264 LEU LEU B . n 
B 1 175 SER 175 265 265 SER SER B . n 
B 1 176 ARG 176 266 266 ARG ARG B . n 
B 1 177 ASN 177 267 267 ASN ASN B . n 
B 1 178 ASN 178 268 268 ASN ASN B . n 
B 1 179 ASN 179 269 269 ASN ASN B . n 
B 1 180 MET 180 270 270 MET MET B . n 
B 1 181 ILE 181 271 271 ILE ILE B . n 
B 1 182 MET 182 272 272 MET MET B . n 
B 1 183 ARG 183 273 273 ARG ARG B . n 
B 1 184 SER 184 274 274 SER SER B . n 
B 1 185 PHE 185 275 275 PHE PHE B . n 
B 1 186 ARG 186 276 276 ARG ARG B . n 
B 1 187 GLN 187 277 277 GLN GLN B . n 
B 1 188 PRO 188 278 278 PRO PRO B . n 
B 1 189 ILE 189 279 279 ILE ILE B . n 
B 1 190 THR 190 280 280 THR THR B . n 
B 1 191 GLU 191 281 281 GLU GLU B . n 
B 1 192 VAL 192 282 282 VAL VAL B . n 
B 1 193 PRO 193 283 283 PRO PRO B . n 
B 1 194 PHE 194 284 284 PHE PHE B . n 
B 1 195 PHE 195 285 285 PHE PHE B . n 
B 1 196 ASN 196 286 286 ASN ASN B . n 
B 1 197 GLY 197 287 287 GLY GLY B . n 
B 1 198 ASP 198 288 288 ASP ASP B . n 
B 1 199 ILE 199 289 289 ILE ILE B . n 
B 1 200 PRO 200 290 290 PRO PRO B . n 
B 1 201 ASP 201 291 291 ASP ASP B . n 
B 1 202 PRO 202 292 292 PRO PRO B . n 
B 1 203 ASN 203 293 293 ASN ASN B . n 
B 1 204 LEU 204 294 294 LEU LEU B . n 
B 1 205 PRO 205 295 295 PRO PRO B . n 
B 1 206 ARG 206 296 296 ARG ARG B . n 
B 1 207 ILE 207 297 297 ILE ILE B . n 
B 1 208 THR 208 298 298 THR THR B . n 
B 1 209 ARG 209 299 299 ARG ARG B . n 
B 1 210 ILE 210 300 300 ILE ILE B . n 
B 1 211 GLU 211 301 301 GLU GLU B . n 
B 1 212 ASP 212 302 302 ASP ASP B . n 
B 1 213 ILE 213 303 303 ILE ILE B . n 
B 1 214 ASP 214 304 304 ASP ASP B . n 
B 1 215 SER 215 305 305 SER SER B . n 
B 1 216 LEU 216 306 306 LEU LEU B . n 
B 1 217 SER 217 307 307 SER SER B . n 
B 1 218 GLU 218 308 308 GLU GLU B . n 
B 1 219 GLU 219 309 309 GLU GLU B . n 
B 1 220 ASN 220 310 310 ASN ASN B . n 
B 1 221 CYS 221 311 311 CYS CYS B . n 
B 1 222 THR 222 312 312 THR THR B . n 
B 1 223 ARG 223 313 313 ARG ARG B . n 
B 1 224 TYR 224 314 314 TYR TYR B . n 
B 1 225 LEU 225 315 315 LEU LEU B . n 
B 1 226 LYS 226 316 316 LYS LYS B . n 
B 1 227 GLY 227 317 317 GLY GLY B . n 
B 1 228 TYR 228 318 318 TYR TYR B . n 
B 1 229 GLY 229 319 319 GLY GLY B . n 
B 1 230 VAL 230 320 320 VAL VAL B . n 
B 1 231 SER 231 321 321 SER SER B . n 
B 1 232 TYR 232 322 322 TYR TYR B . n 
B 1 233 ASP 233 323 323 ASP ASP B . n 
B 1 234 GLU 234 324 324 GLU GLU B . n 
B 1 235 ASN 235 325 325 ASN ASN B . n 
B 1 236 ASP 236 326 326 ASP ASP B . n 
B 1 237 GLN 237 327 327 GLN GLN B . n 
B 1 238 SER 238 328 328 SER SER B . n 
B 1 239 LEU 239 329 329 LEU LEU B . n 
B 1 240 TRP 240 330 330 TRP TRP B . n 
B 1 241 LYS 241 331 331 LYS LYS B . n 
B 1 242 ARG 242 332 332 ARG ARG B . n 
B 1 243 GLN 243 333 333 GLN GLN B . n 
B 1 244 LEU 244 334 334 LEU LEU B . n 
B 1 245 ALA 245 335 335 ALA ALA B . n 
B 1 246 LYS 246 336 336 LYS LYS B . n 
B 1 247 ALA 247 337 337 ALA ALA B . n 
B 1 248 VAL 248 338 338 VAL VAL B . n 
B 1 249 GLY 249 339 339 GLY GLY B . n 
B 1 250 LEU 250 340 340 LEU LEU B . n 
B 1 251 THR 251 341 341 THR THR B . n 
B 1 252 ALA 252 342 342 ALA ALA B . n 
B 1 253 ALA 253 343 343 ALA ALA B . n 
B 1 254 TYR 254 344 344 TYR TYR B . n 
B 1 255 ASP 255 345 345 ASP ASP B . n 
B 1 256 ALA 256 346 346 ALA ALA B . n 
B 1 257 SER 257 347 347 SER SER B . n 
B 1 258 TYR 258 348 348 TYR TYR B . n 
B 1 259 THR 259 349 349 THR THR B . n 
B 1 260 PHE 260 350 350 PHE PHE B . n 
B 1 261 SER 261 351 351 SER SER B . n 
B 1 262 PRO 262 352 352 PRO PRO B . n 
B 1 263 PHE 263 353 353 PHE PHE B . n 
B 1 264 SER 264 354 354 SER SER B . n 
B 1 265 SER 265 355 ?   ?   ?   B . n 
B 1 266 SER 266 356 ?   ?   ?   B . n 
B 1 267 GLU 267 357 ?   ?   ?   B . n 
B 1 268 SER 268 358 ?   ?   ?   B . n 
B 1 269 GLY 269 359 ?   ?   ?   B . n 
B 1 270 GLY 270 360 ?   ?   ?   B . n 
B 1 271 GLY 271 361 ?   ?   ?   B . n 
B 1 272 SER 272 362 ?   ?   ?   B . n 
B 1 273 SER 273 363 ?   ?   ?   B . n 
B 1 274 GLY 274 364 ?   ?   ?   B . n 
B 1 275 GLY 275 365 ?   ?   ?   B . n 
B 1 276 GLY 276 366 ?   ?   ?   B . n 
B 1 277 SER 277 367 ?   ?   ?   B . n 
B 1 278 THR 278 368 ?   ?   ?   B . n 
B 1 279 TYR 279 369 ?   ?   ?   B . n 
B 1 280 LYS 280 370 ?   ?   ?   B . n 
B 1 281 LEU 281 371 ?   ?   ?   B . n 
B 1 282 ILE 282 372 ?   ?   ?   B . n 
B 1 283 LEU 283 373 ?   ?   ?   B . n 
B 1 284 ASN 284 374 ?   ?   ?   B . n 
B 1 285 GLY 285 375 ?   ?   ?   B . n 
B 1 286 LYS 286 376 ?   ?   ?   B . n 
B 1 287 THR 287 377 ?   ?   ?   B . n 
B 1 288 LEU 288 378 ?   ?   ?   B . n 
B 1 289 LYS 289 379 ?   ?   ?   B . n 
B 1 290 GLY 290 380 ?   ?   ?   B . n 
B 1 291 GLU 291 381 ?   ?   ?   B . n 
B 1 292 THR 292 382 ?   ?   ?   B . n 
B 1 293 THR 293 383 ?   ?   ?   B . n 
B 1 294 THR 294 384 ?   ?   ?   B . n 
B 1 295 GLU 295 385 ?   ?   ?   B . n 
B 1 296 ALA 296 386 ?   ?   ?   B . n 
B 1 297 VAL 297 387 ?   ?   ?   B . n 
B 1 298 ASP 298 388 ?   ?   ?   B . n 
B 1 299 ALA 299 389 ?   ?   ?   B . n 
B 1 300 ALA 300 390 ?   ?   ?   B . n 
B 1 301 THR 301 391 ?   ?   ?   B . n 
B 1 302 ALA 302 392 ?   ?   ?   B . n 
B 1 303 GLU 303 393 ?   ?   ?   B . n 
B 1 304 LYS 304 394 ?   ?   ?   B . n 
B 1 305 VAL 305 395 ?   ?   ?   B . n 
B 1 306 PHE 306 396 ?   ?   ?   B . n 
B 1 307 LYS 307 397 ?   ?   ?   B . n 
B 1 308 GLN 308 398 ?   ?   ?   B . n 
B 1 309 TYR 309 399 ?   ?   ?   B . n 
B 1 310 ALA 310 400 ?   ?   ?   B . n 
B 1 311 ASN 311 401 ?   ?   ?   B . n 
B 1 312 ASP 312 402 ?   ?   ?   B . n 
B 1 313 ASN 313 403 ?   ?   ?   B . n 
B 1 314 GLY 314 404 ?   ?   ?   B . n 
B 1 315 VAL 315 405 ?   ?   ?   B . n 
B 1 316 ASP 316 406 ?   ?   ?   B . n 
B 1 317 GLY 317 407 ?   ?   ?   B . n 
B 1 318 GLU 318 408 ?   ?   ?   B . n 
B 1 319 TRP 319 409 ?   ?   ?   B . n 
B 1 320 THR 320 410 ?   ?   ?   B . n 
B 1 321 TYR 321 411 ?   ?   ?   B . n 
B 1 322 ASP 322 412 ?   ?   ?   B . n 
B 1 323 ASP 323 413 ?   ?   ?   B . n 
B 1 324 ALA 324 414 ?   ?   ?   B . n 
B 1 325 THR 325 415 ?   ?   ?   B . n 
B 1 326 LYS 326 416 ?   ?   ?   B . n 
B 1 327 THR 327 417 ?   ?   ?   B . n 
B 1 328 PHE 328 418 ?   ?   ?   B . n 
B 1 329 THR 329 419 ?   ?   ?   B . n 
B 1 330 VAL 330 420 ?   ?   ?   B . n 
B 1 331 THR 331 421 ?   ?   ?   B . n 
B 1 332 GLU 332 422 ?   ?   ?   B . n 
C 1 1   MET 1   91  ?   ?   ?   C . n 
C 1 2   SER 2   92  ?   ?   ?   C . n 
C 1 3   GLU 3   93  ?   ?   ?   C . n 
C 1 4   GLU 4   94  ?   ?   ?   C . n 
C 1 5   ASP 5   95  ?   ?   ?   C . n 
C 1 6   ASN 6   96  ?   ?   ?   C . n 
C 1 7   ARG 7   97  ?   ?   ?   C . n 
C 1 8   LEU 8   98  ?   ?   ?   C . n 
C 1 9   ASN 9   99  ?   ?   ?   C . n 
C 1 10  GLU 10  100 ?   ?   ?   C . n 
C 1 11  LEU 11  101 ?   ?   ?   C . n 
C 1 12  PHE 12  102 ?   ?   ?   C . n 
C 1 13  ALA 13  103 ?   ?   ?   C . n 
C 1 14  ASN 14  104 ?   ?   ?   C . n 
C 1 15  ASP 15  105 ?   ?   ?   C . n 
C 1 16  LEU 16  106 ?   ?   ?   C . n 
C 1 17  GLY 17  107 ?   ?   ?   C . n 
C 1 18  VAL 18  108 ?   ?   ?   C . n 
C 1 19  GLN 19  109 ?   ?   ?   C . n 
C 1 20  PRO 20  110 ?   ?   ?   C . n 
C 1 21  PRO 21  111 ?   ?   ?   C . n 
C 1 22  CYS 22  112 ?   ?   ?   C . n 
C 1 23  GLU 23  113 ?   ?   ?   C . n 
C 1 24  ARG 24  114 ?   ?   ?   C . n 
C 1 25  SER 25  115 ?   ?   ?   C . n 
C 1 26  LEU 26  116 ?   ?   ?   C . n 
C 1 27  LYS 27  117 ?   ?   ?   C . n 
C 1 28  GLU 28  118 ?   ?   ?   C . n 
C 1 29  GLY 29  119 ?   ?   ?   C . n 
C 1 30  ARG 30  120 ?   ?   ?   C . n 
C 1 31  ARG 31  121 ?   ?   ?   C . n 
C 1 32  PHE 32  122 ?   ?   ?   C . n 
C 1 33  LEU 33  123 ?   ?   ?   C . n 
C 1 34  ASN 34  124 ?   ?   ?   C . n 
C 1 35  ASP 35  125 ?   ?   ?   C . n 
C 1 36  PHE 36  126 ?   ?   ?   C . n 
C 1 37  GLU 37  127 ?   ?   ?   C . n 
C 1 38  ILE 38  128 ?   ?   ?   C . n 
C 1 39  ALA 39  129 ?   ?   ?   C . n 
C 1 40  ALA 40  130 ?   ?   ?   C . n 
C 1 41  LYS 41  131 ?   ?   ?   C . n 
C 1 42  LYS 42  132 ?   ?   ?   C . n 
C 1 43  LYS 43  133 ?   ?   ?   C . n 
C 1 44  LEU 44  134 ?   ?   ?   C . n 
C 1 45  LEU 45  135 ?   ?   ?   C . n 
C 1 46  GLU 46  136 ?   ?   ?   C . n 
C 1 47  LEU 47  137 ?   ?   ?   C . n 
C 1 48  GLU 48  138 ?   ?   ?   C . n 
C 1 49  ARG 49  139 ?   ?   ?   C . n 
C 1 50  LYS 50  140 ?   ?   ?   C . n 
C 1 51  ALA 51  141 ?   ?   ?   C . n 
C 1 52  LEU 52  142 ?   ?   ?   C . n 
C 1 53  GLU 53  143 ?   ?   ?   C . n 
C 1 54  ASP 54  144 ?   ?   ?   C . n 
C 1 55  LYS 55  145 ?   ?   ?   C . n 
C 1 56  GLU 56  146 ?   ?   ?   C . n 
C 1 57  LYS 57  147 ?   ?   ?   C . n 
C 1 58  ASN 58  148 ?   ?   ?   C . n 
C 1 59  LEU 59  149 ?   ?   ?   C . n 
C 1 60  ASN 60  150 ?   ?   ?   C . n 
C 1 61  PHE 61  151 ?   ?   ?   C . n 
C 1 62  VAL 62  152 ?   ?   ?   C . n 
C 1 63  VAL 63  153 ?   ?   ?   C . n 
C 1 64  GLU 64  154 ?   ?   ?   C . n 
C 1 65  SER 65  155 ?   ?   ?   C . n 
C 1 66  GLU 66  156 ?   ?   ?   C . n 
C 1 67  ARG 67  157 ?   ?   ?   C . n 
C 1 68  THR 68  158 ?   ?   ?   C . n 
C 1 69  LEU 69  159 ?   ?   ?   C . n 
C 1 70  PHE 70  160 ?   ?   ?   C . n 
C 1 71  ASN 71  161 ?   ?   ?   C . n 
C 1 72  SER 72  162 ?   ?   ?   C . n 
C 1 73  LYS 73  163 ?   ?   ?   C . n 
C 1 74  LYS 74  164 ?   ?   ?   C . n 
C 1 75  ARG 75  165 ?   ?   ?   C . n 
C 1 76  ALA 76  166 ?   ?   ?   C . n 
C 1 77  PHE 77  167 ?   ?   ?   C . n 
C 1 78  ASP 78  168 ?   ?   ?   C . n 
C 1 79  ASN 79  169 ?   ?   ?   C . n 
C 1 80  ASP 80  170 ?   ?   ?   C . n 
C 1 81  GLU 81  171 ?   ?   ?   C . n 
C 1 82  CYS 82  172 ?   ?   ?   C . n 
C 1 83  TYR 83  173 ?   ?   ?   C . n 
C 1 84  ASN 84  174 ?   ?   ?   C . n 
C 1 85  ASP 85  175 ?   ?   ?   C . n 
C 1 86  ARG 86  176 ?   ?   ?   C . n 
C 1 87  CYS 87  177 ?   ?   ?   C . n 
C 1 88  LYS 88  178 ?   ?   ?   C . n 
C 1 89  LEU 89  179 ?   ?   ?   C . n 
C 1 90  PHE 90  180 ?   ?   ?   C . n 
C 1 91  ARG 91  181 ?   ?   ?   C . n 
C 1 92  GLY 92  182 ?   ?   ?   C . n 
C 1 93  ILE 93  183 ?   ?   ?   C . n 
C 1 94  VAL 94  184 ?   ?   ?   C . n 
C 1 95  ASN 95  185 ?   ?   ?   C . n 
C 1 96  GLU 96  186 ?   ?   ?   C . n 
C 1 97  TRP 97  187 ?   ?   ?   C . n 
C 1 98  GLY 98  188 ?   ?   ?   C . n 
C 1 99  ARG 99  189 ?   ?   ?   C . n 
C 1 100 SER 100 190 ?   ?   ?   C . n 
C 1 101 GLU 101 191 ?   ?   ?   C . n 
C 1 102 ARG 102 192 ?   ?   ?   C . n 
C 1 103 THR 103 193 ?   ?   ?   C . n 
C 1 104 LEU 104 194 ?   ?   ?   C . n 
C 1 105 ASP 105 195 ?   ?   ?   C . n 
C 1 106 SER 106 196 ?   ?   ?   C . n 
C 1 107 LEU 107 197 ?   ?   ?   C . n 
C 1 108 ASP 108 198 ?   ?   ?   C . n 
C 1 109 GLU 109 199 ?   ?   ?   C . n 
C 1 110 PRO 110 200 ?   ?   ?   C . n 
C 1 111 PRO 111 201 ?   ?   ?   C . n 
C 1 112 ALA 112 202 ?   ?   ?   C . n 
C 1 113 TRP 113 203 ?   ?   ?   C . n 
C 1 114 PHE 114 204 ?   ?   ?   C . n 
C 1 115 ARG 115 205 ?   ?   ?   C . n 
C 1 116 ARG 116 206 ?   ?   ?   C . n 
C 1 117 GLU 117 207 ?   ?   ?   C . n 
C 1 118 MET 118 208 208 MET MET C . n 
C 1 119 GLY 119 209 209 GLY GLY C . n 
C 1 120 GLU 120 210 210 GLU GLU C . n 
C 1 121 TRP 121 211 211 TRP TRP C . n 
C 1 122 LYS 122 212 212 LYS LYS C . n 
C 1 123 LYS 123 213 213 LYS LYS C . n 
C 1 124 ALA 124 214 214 ALA ALA C . n 
C 1 125 ARG 125 215 215 ARG ARG C . n 
C 1 126 GLU 126 216 216 GLU GLU C . n 
C 1 127 GLU 127 217 217 GLU GLU C . n 
C 1 128 ASP 128 218 218 ASP ASP C . n 
C 1 129 LYS 129 219 219 LYS LYS C . n 
C 1 130 GLU 130 220 220 GLU GLU C . n 
C 1 131 TRP 131 221 221 TRP TRP C . n 
C 1 132 ARG 132 222 222 ARG ARG C . n 
C 1 133 LYS 133 223 223 LYS LYS C . n 
C 1 134 SER 134 224 224 SER SER C . n 
C 1 135 THR 135 225 225 THR THR C . n 
C 1 136 ASP 136 226 226 ASP ASP C . n 
C 1 137 GLU 137 227 227 GLU GLU C . n 
C 1 138 ARG 138 228 228 ARG ARG C . n 
C 1 139 LEU 139 229 229 LEU LEU C . n 
C 1 140 GLU 140 230 230 GLU GLU C . n 
C 1 141 ASN 141 231 231 ASN ASN C . n 
C 1 142 LEU 142 232 232 LEU LEU C . n 
C 1 143 LEU 143 233 233 LEU LEU C . n 
C 1 144 ASN 144 234 234 ASN ASN C . n 
C 1 145 ILE 145 235 235 ILE ILE C . n 
C 1 146 VAL 146 236 236 VAL VAL C . n 
C 1 147 ARG 147 237 237 ARG ARG C . n 
C 1 148 GLU 148 238 238 GLU GLU C . n 
C 1 149 ILE 149 239 239 ILE ILE C . n 
C 1 150 LEU 150 240 240 LEU LEU C . n 
C 1 151 ASP 151 241 241 ASP ASP C . n 
C 1 152 VAL 152 242 242 VAL VAL C . n 
C 1 153 GLN 153 243 243 GLN GLN C . n 
C 1 154 ARG 154 244 244 ARG ARG C . n 
C 1 155 ASP 155 245 245 ASP ASP C . n 
C 1 156 MET 156 246 246 MET MET C . n 
C 1 157 ARG 157 247 247 ARG ARG C . n 
C 1 158 ASN 158 248 248 ASN ASN C . n 
C 1 159 ASP 159 249 249 ASP ASP C . n 
C 1 160 LEU 160 250 250 LEU LEU C . n 
C 1 161 SER 161 251 251 SER SER C . n 
C 1 162 ASN 162 252 252 ASN ASN C . n 
C 1 163 LEU 163 253 253 LEU LEU C . n 
C 1 164 THR 164 254 254 THR THR C . n 
C 1 165 ARG 165 255 255 ARG ARG C . n 
C 1 166 LYS 166 256 256 LYS LYS C . n 
C 1 167 VAL 167 257 257 VAL VAL C . n 
C 1 168 ASP 168 258 258 ASP ASP C . n 
C 1 169 ARG 169 259 259 ARG ARG C . n 
C 1 170 MET 170 260 260 MET MET C . n 
C 1 171 ASP 171 261 261 ASP ASP C . n 
C 1 172 MET 172 262 262 MET MET C . n 
C 1 173 ARG 173 263 263 ARG ARG C . n 
C 1 174 LEU 174 264 264 LEU LEU C . n 
C 1 175 SER 175 265 265 SER SER C . n 
C 1 176 ARG 176 266 266 ARG ARG C . n 
C 1 177 ASN 177 267 267 ASN ASN C . n 
C 1 178 ASN 178 268 268 ASN ASN C . n 
C 1 179 ASN 179 269 269 ASN ASN C . n 
C 1 180 MET 180 270 270 MET MET C . n 
C 1 181 ILE 181 271 271 ILE ILE C . n 
C 1 182 MET 182 272 272 MET MET C . n 
C 1 183 ARG 183 273 273 ARG ARG C . n 
C 1 184 SER 184 274 274 SER SER C . n 
C 1 185 PHE 185 275 275 PHE PHE C . n 
C 1 186 ARG 186 276 276 ARG ARG C . n 
C 1 187 GLN 187 277 277 GLN GLN C . n 
C 1 188 PRO 188 278 278 PRO PRO C . n 
C 1 189 ILE 189 279 279 ILE ILE C . n 
C 1 190 THR 190 280 280 THR THR C . n 
C 1 191 GLU 191 281 281 GLU GLU C . n 
C 1 192 VAL 192 282 282 VAL VAL C . n 
C 1 193 PRO 193 283 283 PRO PRO C . n 
C 1 194 PHE 194 284 284 PHE PHE C . n 
C 1 195 PHE 195 285 285 PHE PHE C . n 
C 1 196 ASN 196 286 286 ASN ASN C . n 
C 1 197 GLY 197 287 287 GLY GLY C . n 
C 1 198 ASP 198 288 288 ASP ASP C . n 
C 1 199 ILE 199 289 289 ILE ILE C . n 
C 1 200 PRO 200 290 290 PRO PRO C . n 
C 1 201 ASP 201 291 291 ASP ASP C . n 
C 1 202 PRO 202 292 292 PRO PRO C . n 
C 1 203 ASN 203 293 293 ASN ASN C . n 
C 1 204 LEU 204 294 294 LEU LEU C . n 
C 1 205 PRO 205 295 295 PRO PRO C . n 
C 1 206 ARG 206 296 296 ARG ARG C . n 
C 1 207 ILE 207 297 297 ILE ILE C . n 
C 1 208 THR 208 298 298 THR THR C . n 
C 1 209 ARG 209 299 299 ARG ARG C . n 
C 1 210 ILE 210 300 300 ILE ILE C . n 
C 1 211 GLU 211 301 301 GLU GLU C . n 
C 1 212 ASP 212 302 302 ASP ASP C . n 
C 1 213 ILE 213 303 303 ILE ILE C . n 
C 1 214 ASP 214 304 304 ASP ASP C . n 
C 1 215 SER 215 305 305 SER SER C . n 
C 1 216 LEU 216 306 306 LEU LEU C . n 
C 1 217 SER 217 307 307 SER SER C . n 
C 1 218 GLU 218 308 308 GLU GLU C . n 
C 1 219 GLU 219 309 309 GLU GLU C . n 
C 1 220 ASN 220 310 310 ASN ASN C . n 
C 1 221 CYS 221 311 311 CYS CYS C . n 
C 1 222 THR 222 312 312 THR THR C . n 
C 1 223 ARG 223 313 313 ARG ARG C . n 
C 1 224 TYR 224 314 314 TYR TYR C . n 
C 1 225 LEU 225 315 315 LEU LEU C . n 
C 1 226 LYS 226 316 316 LYS LYS C . n 
C 1 227 GLY 227 317 317 GLY GLY C . n 
C 1 228 TYR 228 318 318 TYR TYR C . n 
C 1 229 GLY 229 319 319 GLY GLY C . n 
C 1 230 VAL 230 320 320 VAL VAL C . n 
C 1 231 SER 231 321 321 SER SER C . n 
C 1 232 TYR 232 322 322 TYR TYR C . n 
C 1 233 ASP 233 323 323 ASP ASP C . n 
C 1 234 GLU 234 324 324 GLU GLU C . n 
C 1 235 ASN 235 325 325 ASN ASN C . n 
C 1 236 ASP 236 326 326 ASP ASP C . n 
C 1 237 GLN 237 327 327 GLN GLN C . n 
C 1 238 SER 238 328 328 SER SER C . n 
C 1 239 LEU 239 329 329 LEU LEU C . n 
C 1 240 TRP 240 330 330 TRP TRP C . n 
C 1 241 LYS 241 331 331 LYS LYS C . n 
C 1 242 ARG 242 332 332 ARG ARG C . n 
C 1 243 GLN 243 333 333 GLN GLN C . n 
C 1 244 LEU 244 334 334 LEU LEU C . n 
C 1 245 ALA 245 335 335 ALA ALA C . n 
C 1 246 LYS 246 336 336 LYS LYS C . n 
C 1 247 ALA 247 337 337 ALA ALA C . n 
C 1 248 VAL 248 338 338 VAL VAL C . n 
C 1 249 GLY 249 339 339 GLY GLY C . n 
C 1 250 LEU 250 340 340 LEU LEU C . n 
C 1 251 THR 251 341 341 THR THR C . n 
C 1 252 ALA 252 342 342 ALA ALA C . n 
C 1 253 ALA 253 343 343 ALA ALA C . n 
C 1 254 TYR 254 344 344 TYR TYR C . n 
C 1 255 ASP 255 345 345 ASP ASP C . n 
C 1 256 ALA 256 346 346 ALA ALA C . n 
C 1 257 SER 257 347 347 SER SER C . n 
C 1 258 TYR 258 348 348 TYR TYR C . n 
C 1 259 THR 259 349 349 THR THR C . n 
C 1 260 PHE 260 350 350 PHE PHE C . n 
C 1 261 SER 261 351 351 SER SER C . n 
C 1 262 PRO 262 352 352 PRO PRO C . n 
C 1 263 PHE 263 353 353 PHE PHE C . n 
C 1 264 SER 264 354 354 SER SER C . n 
C 1 265 SER 265 355 ?   ?   ?   C . n 
C 1 266 SER 266 356 ?   ?   ?   C . n 
C 1 267 GLU 267 357 ?   ?   ?   C . n 
C 1 268 SER 268 358 ?   ?   ?   C . n 
C 1 269 GLY 269 359 ?   ?   ?   C . n 
C 1 270 GLY 270 360 ?   ?   ?   C . n 
C 1 271 GLY 271 361 ?   ?   ?   C . n 
C 1 272 SER 272 362 ?   ?   ?   C . n 
C 1 273 SER 273 363 ?   ?   ?   C . n 
C 1 274 GLY 274 364 ?   ?   ?   C . n 
C 1 275 GLY 275 365 ?   ?   ?   C . n 
C 1 276 GLY 276 366 ?   ?   ?   C . n 
C 1 277 SER 277 367 ?   ?   ?   C . n 
C 1 278 THR 278 368 ?   ?   ?   C . n 
C 1 279 TYR 279 369 ?   ?   ?   C . n 
C 1 280 LYS 280 370 ?   ?   ?   C . n 
C 1 281 LEU 281 371 ?   ?   ?   C . n 
C 1 282 ILE 282 372 ?   ?   ?   C . n 
C 1 283 LEU 283 373 ?   ?   ?   C . n 
C 1 284 ASN 284 374 ?   ?   ?   C . n 
C 1 285 GLY 285 375 ?   ?   ?   C . n 
C 1 286 LYS 286 376 ?   ?   ?   C . n 
C 1 287 THR 287 377 ?   ?   ?   C . n 
C 1 288 LEU 288 378 ?   ?   ?   C . n 
C 1 289 LYS 289 379 ?   ?   ?   C . n 
C 1 290 GLY 290 380 ?   ?   ?   C . n 
C 1 291 GLU 291 381 ?   ?   ?   C . n 
C 1 292 THR 292 382 ?   ?   ?   C . n 
C 1 293 THR 293 383 ?   ?   ?   C . n 
C 1 294 THR 294 384 ?   ?   ?   C . n 
C 1 295 GLU 295 385 ?   ?   ?   C . n 
C 1 296 ALA 296 386 ?   ?   ?   C . n 
C 1 297 VAL 297 387 ?   ?   ?   C . n 
C 1 298 ASP 298 388 ?   ?   ?   C . n 
C 1 299 ALA 299 389 ?   ?   ?   C . n 
C 1 300 ALA 300 390 ?   ?   ?   C . n 
C 1 301 THR 301 391 ?   ?   ?   C . n 
C 1 302 ALA 302 392 ?   ?   ?   C . n 
C 1 303 GLU 303 393 ?   ?   ?   C . n 
C 1 304 LYS 304 394 ?   ?   ?   C . n 
C 1 305 VAL 305 395 ?   ?   ?   C . n 
C 1 306 PHE 306 396 ?   ?   ?   C . n 
C 1 307 LYS 307 397 ?   ?   ?   C . n 
C 1 308 GLN 308 398 ?   ?   ?   C . n 
C 1 309 TYR 309 399 ?   ?   ?   C . n 
C 1 310 ALA 310 400 ?   ?   ?   C . n 
C 1 311 ASN 311 401 ?   ?   ?   C . n 
C 1 312 ASP 312 402 ?   ?   ?   C . n 
C 1 313 ASN 313 403 ?   ?   ?   C . n 
C 1 314 GLY 314 404 ?   ?   ?   C . n 
C 1 315 VAL 315 405 ?   ?   ?   C . n 
C 1 316 ASP 316 406 ?   ?   ?   C . n 
C 1 317 GLY 317 407 ?   ?   ?   C . n 
C 1 318 GLU 318 408 ?   ?   ?   C . n 
C 1 319 TRP 319 409 ?   ?   ?   C . n 
C 1 320 THR 320 410 ?   ?   ?   C . n 
C 1 321 TYR 321 411 ?   ?   ?   C . n 
C 1 322 ASP 322 412 ?   ?   ?   C . n 
C 1 323 ASP 323 413 ?   ?   ?   C . n 
C 1 324 ALA 324 414 ?   ?   ?   C . n 
C 1 325 THR 325 415 ?   ?   ?   C . n 
C 1 326 LYS 326 416 ?   ?   ?   C . n 
C 1 327 THR 327 417 ?   ?   ?   C . n 
C 1 328 PHE 328 418 ?   ?   ?   C . n 
C 1 329 THR 329 419 ?   ?   ?   C . n 
C 1 330 VAL 330 420 ?   ?   ?   C . n 
C 1 331 THR 331 421 ?   ?   ?   C . n 
C 1 332 GLU 332 422 ?   ?   ?   C . n 
D 1 1   MET 1   91  ?   ?   ?   D . n 
D 1 2   SER 2   92  ?   ?   ?   D . n 
D 1 3   GLU 3   93  ?   ?   ?   D . n 
D 1 4   GLU 4   94  ?   ?   ?   D . n 
D 1 5   ASP 5   95  ?   ?   ?   D . n 
D 1 6   ASN 6   96  ?   ?   ?   D . n 
D 1 7   ARG 7   97  ?   ?   ?   D . n 
D 1 8   LEU 8   98  ?   ?   ?   D . n 
D 1 9   ASN 9   99  ?   ?   ?   D . n 
D 1 10  GLU 10  100 ?   ?   ?   D . n 
D 1 11  LEU 11  101 ?   ?   ?   D . n 
D 1 12  PHE 12  102 ?   ?   ?   D . n 
D 1 13  ALA 13  103 ?   ?   ?   D . n 
D 1 14  ASN 14  104 ?   ?   ?   D . n 
D 1 15  ASP 15  105 ?   ?   ?   D . n 
D 1 16  LEU 16  106 ?   ?   ?   D . n 
D 1 17  GLY 17  107 ?   ?   ?   D . n 
D 1 18  VAL 18  108 ?   ?   ?   D . n 
D 1 19  GLN 19  109 ?   ?   ?   D . n 
D 1 20  PRO 20  110 ?   ?   ?   D . n 
D 1 21  PRO 21  111 ?   ?   ?   D . n 
D 1 22  CYS 22  112 ?   ?   ?   D . n 
D 1 23  GLU 23  113 ?   ?   ?   D . n 
D 1 24  ARG 24  114 ?   ?   ?   D . n 
D 1 25  SER 25  115 ?   ?   ?   D . n 
D 1 26  LEU 26  116 ?   ?   ?   D . n 
D 1 27  LYS 27  117 ?   ?   ?   D . n 
D 1 28  GLU 28  118 ?   ?   ?   D . n 
D 1 29  GLY 29  119 ?   ?   ?   D . n 
D 1 30  ARG 30  120 ?   ?   ?   D . n 
D 1 31  ARG 31  121 ?   ?   ?   D . n 
D 1 32  PHE 32  122 ?   ?   ?   D . n 
D 1 33  LEU 33  123 ?   ?   ?   D . n 
D 1 34  ASN 34  124 ?   ?   ?   D . n 
D 1 35  ASP 35  125 ?   ?   ?   D . n 
D 1 36  PHE 36  126 ?   ?   ?   D . n 
D 1 37  GLU 37  127 ?   ?   ?   D . n 
D 1 38  ILE 38  128 ?   ?   ?   D . n 
D 1 39  ALA 39  129 ?   ?   ?   D . n 
D 1 40  ALA 40  130 ?   ?   ?   D . n 
D 1 41  LYS 41  131 ?   ?   ?   D . n 
D 1 42  LYS 42  132 ?   ?   ?   D . n 
D 1 43  LYS 43  133 ?   ?   ?   D . n 
D 1 44  LEU 44  134 ?   ?   ?   D . n 
D 1 45  LEU 45  135 ?   ?   ?   D . n 
D 1 46  GLU 46  136 ?   ?   ?   D . n 
D 1 47  LEU 47  137 ?   ?   ?   D . n 
D 1 48  GLU 48  138 ?   ?   ?   D . n 
D 1 49  ARG 49  139 ?   ?   ?   D . n 
D 1 50  LYS 50  140 ?   ?   ?   D . n 
D 1 51  ALA 51  141 ?   ?   ?   D . n 
D 1 52  LEU 52  142 ?   ?   ?   D . n 
D 1 53  GLU 53  143 ?   ?   ?   D . n 
D 1 54  ASP 54  144 ?   ?   ?   D . n 
D 1 55  LYS 55  145 ?   ?   ?   D . n 
D 1 56  GLU 56  146 ?   ?   ?   D . n 
D 1 57  LYS 57  147 ?   ?   ?   D . n 
D 1 58  ASN 58  148 ?   ?   ?   D . n 
D 1 59  LEU 59  149 ?   ?   ?   D . n 
D 1 60  ASN 60  150 ?   ?   ?   D . n 
D 1 61  PHE 61  151 ?   ?   ?   D . n 
D 1 62  VAL 62  152 ?   ?   ?   D . n 
D 1 63  VAL 63  153 ?   ?   ?   D . n 
D 1 64  GLU 64  154 ?   ?   ?   D . n 
D 1 65  SER 65  155 ?   ?   ?   D . n 
D 1 66  GLU 66  156 ?   ?   ?   D . n 
D 1 67  ARG 67  157 ?   ?   ?   D . n 
D 1 68  THR 68  158 ?   ?   ?   D . n 
D 1 69  LEU 69  159 ?   ?   ?   D . n 
D 1 70  PHE 70  160 ?   ?   ?   D . n 
D 1 71  ASN 71  161 ?   ?   ?   D . n 
D 1 72  SER 72  162 ?   ?   ?   D . n 
D 1 73  LYS 73  163 ?   ?   ?   D . n 
D 1 74  LYS 74  164 ?   ?   ?   D . n 
D 1 75  ARG 75  165 ?   ?   ?   D . n 
D 1 76  ALA 76  166 ?   ?   ?   D . n 
D 1 77  PHE 77  167 ?   ?   ?   D . n 
D 1 78  ASP 78  168 ?   ?   ?   D . n 
D 1 79  ASN 79  169 ?   ?   ?   D . n 
D 1 80  ASP 80  170 ?   ?   ?   D . n 
D 1 81  GLU 81  171 ?   ?   ?   D . n 
D 1 82  CYS 82  172 ?   ?   ?   D . n 
D 1 83  TYR 83  173 ?   ?   ?   D . n 
D 1 84  ASN 84  174 ?   ?   ?   D . n 
D 1 85  ASP 85  175 ?   ?   ?   D . n 
D 1 86  ARG 86  176 ?   ?   ?   D . n 
D 1 87  CYS 87  177 ?   ?   ?   D . n 
D 1 88  LYS 88  178 ?   ?   ?   D . n 
D 1 89  LEU 89  179 ?   ?   ?   D . n 
D 1 90  PHE 90  180 ?   ?   ?   D . n 
D 1 91  ARG 91  181 ?   ?   ?   D . n 
D 1 92  GLY 92  182 ?   ?   ?   D . n 
D 1 93  ILE 93  183 ?   ?   ?   D . n 
D 1 94  VAL 94  184 ?   ?   ?   D . n 
D 1 95  ASN 95  185 ?   ?   ?   D . n 
D 1 96  GLU 96  186 ?   ?   ?   D . n 
D 1 97  TRP 97  187 ?   ?   ?   D . n 
D 1 98  GLY 98  188 ?   ?   ?   D . n 
D 1 99  ARG 99  189 ?   ?   ?   D . n 
D 1 100 SER 100 190 ?   ?   ?   D . n 
D 1 101 GLU 101 191 ?   ?   ?   D . n 
D 1 102 ARG 102 192 ?   ?   ?   D . n 
D 1 103 THR 103 193 ?   ?   ?   D . n 
D 1 104 LEU 104 194 ?   ?   ?   D . n 
D 1 105 ASP 105 195 ?   ?   ?   D . n 
D 1 106 SER 106 196 ?   ?   ?   D . n 
D 1 107 LEU 107 197 ?   ?   ?   D . n 
D 1 108 ASP 108 198 ?   ?   ?   D . n 
D 1 109 GLU 109 199 ?   ?   ?   D . n 
D 1 110 PRO 110 200 ?   ?   ?   D . n 
D 1 111 PRO 111 201 ?   ?   ?   D . n 
D 1 112 ALA 112 202 ?   ?   ?   D . n 
D 1 113 TRP 113 203 ?   ?   ?   D . n 
D 1 114 PHE 114 204 ?   ?   ?   D . n 
D 1 115 ARG 115 205 ?   ?   ?   D . n 
D 1 116 ARG 116 206 ?   ?   ?   D . n 
D 1 117 GLU 117 207 ?   ?   ?   D . n 
D 1 118 MET 118 208 208 MET MET D . n 
D 1 119 GLY 119 209 209 GLY GLY D . n 
D 1 120 GLU 120 210 210 GLU GLU D . n 
D 1 121 TRP 121 211 211 TRP TRP D . n 
D 1 122 LYS 122 212 212 LYS LYS D . n 
D 1 123 LYS 123 213 213 LYS LYS D . n 
D 1 124 ALA 124 214 214 ALA ALA D . n 
D 1 125 ARG 125 215 215 ARG ARG D . n 
D 1 126 GLU 126 216 216 GLU GLU D . n 
D 1 127 GLU 127 217 217 GLU GLU D . n 
D 1 128 ASP 128 218 218 ASP ASP D . n 
D 1 129 LYS 129 219 219 LYS LYS D . n 
D 1 130 GLU 130 220 220 GLU GLU D . n 
D 1 131 TRP 131 221 221 TRP TRP D . n 
D 1 132 ARG 132 222 222 ARG ARG D . n 
D 1 133 LYS 133 223 223 LYS LYS D . n 
D 1 134 SER 134 224 224 SER SER D . n 
D 1 135 THR 135 225 225 THR THR D . n 
D 1 136 ASP 136 226 226 ASP ASP D . n 
D 1 137 GLU 137 227 227 GLU GLU D . n 
D 1 138 ARG 138 228 228 ARG ARG D . n 
D 1 139 LEU 139 229 229 LEU LEU D . n 
D 1 140 GLU 140 230 230 GLU GLU D . n 
D 1 141 ASN 141 231 231 ASN ASN D . n 
D 1 142 LEU 142 232 232 LEU LEU D . n 
D 1 143 LEU 143 233 233 LEU LEU D . n 
D 1 144 ASN 144 234 234 ASN ASN D . n 
D 1 145 ILE 145 235 235 ILE ILE D . n 
D 1 146 VAL 146 236 236 VAL VAL D . n 
D 1 147 ARG 147 237 237 ARG ARG D . n 
D 1 148 GLU 148 238 238 GLU GLU D . n 
D 1 149 ILE 149 239 239 ILE ILE D . n 
D 1 150 LEU 150 240 240 LEU LEU D . n 
D 1 151 ASP 151 241 241 ASP ASP D . n 
D 1 152 VAL 152 242 242 VAL VAL D . n 
D 1 153 GLN 153 243 243 GLN GLN D . n 
D 1 154 ARG 154 244 244 ARG ARG D . n 
D 1 155 ASP 155 245 245 ASP ASP D . n 
D 1 156 MET 156 246 246 MET MET D . n 
D 1 157 ARG 157 247 247 ARG ARG D . n 
D 1 158 ASN 158 248 248 ASN ASN D . n 
D 1 159 ASP 159 249 249 ASP ASP D . n 
D 1 160 LEU 160 250 250 LEU LEU D . n 
D 1 161 SER 161 251 251 SER SER D . n 
D 1 162 ASN 162 252 252 ASN ASN D . n 
D 1 163 LEU 163 253 253 LEU LEU D . n 
D 1 164 THR 164 254 254 THR THR D . n 
D 1 165 ARG 165 255 255 ARG ARG D . n 
D 1 166 LYS 166 256 256 LYS LYS D . n 
D 1 167 VAL 167 257 257 VAL VAL D . n 
D 1 168 ASP 168 258 258 ASP ASP D . n 
D 1 169 ARG 169 259 259 ARG ARG D . n 
D 1 170 MET 170 260 260 MET MET D . n 
D 1 171 ASP 171 261 261 ASP ASP D . n 
D 1 172 MET 172 262 262 MET MET D . n 
D 1 173 ARG 173 263 263 ARG ARG D . n 
D 1 174 LEU 174 264 264 LEU LEU D . n 
D 1 175 SER 175 265 265 SER SER D . n 
D 1 176 ARG 176 266 266 ARG ARG D . n 
D 1 177 ASN 177 267 267 ASN ASN D . n 
D 1 178 ASN 178 268 268 ASN ASN D . n 
D 1 179 ASN 179 269 269 ASN ASN D . n 
D 1 180 MET 180 270 270 MET MET D . n 
D 1 181 ILE 181 271 271 ILE ILE D . n 
D 1 182 MET 182 272 272 MET MET D . n 
D 1 183 ARG 183 273 273 ARG ARG D . n 
D 1 184 SER 184 274 274 SER SER D . n 
D 1 185 PHE 185 275 275 PHE PHE D . n 
D 1 186 ARG 186 276 276 ARG ARG D . n 
D 1 187 GLN 187 277 277 GLN GLN D . n 
D 1 188 PRO 188 278 278 PRO PRO D . n 
D 1 189 ILE 189 279 279 ILE ILE D . n 
D 1 190 THR 190 280 280 THR THR D . n 
D 1 191 GLU 191 281 281 GLU GLU D . n 
D 1 192 VAL 192 282 282 VAL VAL D . n 
D 1 193 PRO 193 283 283 PRO PRO D . n 
D 1 194 PHE 194 284 284 PHE PHE D . n 
D 1 195 PHE 195 285 285 PHE PHE D . n 
D 1 196 ASN 196 286 286 ASN ASN D . n 
D 1 197 GLY 197 287 287 GLY GLY D . n 
D 1 198 ASP 198 288 288 ASP ASP D . n 
D 1 199 ILE 199 289 289 ILE ILE D . n 
D 1 200 PRO 200 290 290 PRO PRO D . n 
D 1 201 ASP 201 291 291 ASP ASP D . n 
D 1 202 PRO 202 292 292 PRO PRO D . n 
D 1 203 ASN 203 293 293 ASN ASN D . n 
D 1 204 LEU 204 294 294 LEU LEU D . n 
D 1 205 PRO 205 295 295 PRO PRO D . n 
D 1 206 ARG 206 296 296 ARG ARG D . n 
D 1 207 ILE 207 297 297 ILE ILE D . n 
D 1 208 THR 208 298 298 THR THR D . n 
D 1 209 ARG 209 299 299 ARG ARG D . n 
D 1 210 ILE 210 300 300 ILE ILE D . n 
D 1 211 GLU 211 301 301 GLU GLU D . n 
D 1 212 ASP 212 302 302 ASP ASP D . n 
D 1 213 ILE 213 303 303 ILE ILE D . n 
D 1 214 ASP 214 304 304 ASP ASP D . n 
D 1 215 SER 215 305 305 SER SER D . n 
D 1 216 LEU 216 306 306 LEU LEU D . n 
D 1 217 SER 217 307 307 SER SER D . n 
D 1 218 GLU 218 308 308 GLU GLU D . n 
D 1 219 GLU 219 309 309 GLU GLU D . n 
D 1 220 ASN 220 310 310 ASN ASN D . n 
D 1 221 CYS 221 311 311 CYS CYS D . n 
D 1 222 THR 222 312 312 THR THR D . n 
D 1 223 ARG 223 313 313 ARG ARG D . n 
D 1 224 TYR 224 314 314 TYR TYR D . n 
D 1 225 LEU 225 315 315 LEU LEU D . n 
D 1 226 LYS 226 316 316 LYS LYS D . n 
D 1 227 GLY 227 317 317 GLY GLY D . n 
D 1 228 TYR 228 318 318 TYR TYR D . n 
D 1 229 GLY 229 319 319 GLY GLY D . n 
D 1 230 VAL 230 320 320 VAL VAL D . n 
D 1 231 SER 231 321 321 SER SER D . n 
D 1 232 TYR 232 322 322 TYR TYR D . n 
D 1 233 ASP 233 323 323 ASP ASP D . n 
D 1 234 GLU 234 324 324 GLU GLU D . n 
D 1 235 ASN 235 325 325 ASN ASN D . n 
D 1 236 ASP 236 326 326 ASP ASP D . n 
D 1 237 GLN 237 327 327 GLN GLN D . n 
D 1 238 SER 238 328 328 SER SER D . n 
D 1 239 LEU 239 329 329 LEU LEU D . n 
D 1 240 TRP 240 330 330 TRP TRP D . n 
D 1 241 LYS 241 331 331 LYS LYS D . n 
D 1 242 ARG 242 332 332 ARG ARG D . n 
D 1 243 GLN 243 333 333 GLN GLN D . n 
D 1 244 LEU 244 334 334 LEU LEU D . n 
D 1 245 ALA 245 335 335 ALA ALA D . n 
D 1 246 LYS 246 336 336 LYS LYS D . n 
D 1 247 ALA 247 337 337 ALA ALA D . n 
D 1 248 VAL 248 338 338 VAL VAL D . n 
D 1 249 GLY 249 339 339 GLY GLY D . n 
D 1 250 LEU 250 340 340 LEU LEU D . n 
D 1 251 THR 251 341 341 THR THR D . n 
D 1 252 ALA 252 342 342 ALA ALA D . n 
D 1 253 ALA 253 343 343 ALA ALA D . n 
D 1 254 TYR 254 344 344 TYR TYR D . n 
D 1 255 ASP 255 345 345 ASP ASP D . n 
D 1 256 ALA 256 346 346 ALA ALA D . n 
D 1 257 SER 257 347 347 SER SER D . n 
D 1 258 TYR 258 348 348 TYR TYR D . n 
D 1 259 THR 259 349 349 THR THR D . n 
D 1 260 PHE 260 350 350 PHE PHE D . n 
D 1 261 SER 261 351 351 SER SER D . n 
D 1 262 PRO 262 352 352 PRO PRO D . n 
D 1 263 PHE 263 353 353 PHE PHE D . n 
D 1 264 SER 264 354 354 SER SER D . n 
D 1 265 SER 265 355 ?   ?   ?   D . n 
D 1 266 SER 266 356 ?   ?   ?   D . n 
D 1 267 GLU 267 357 ?   ?   ?   D . n 
D 1 268 SER 268 358 ?   ?   ?   D . n 
D 1 269 GLY 269 359 ?   ?   ?   D . n 
D 1 270 GLY 270 360 ?   ?   ?   D . n 
D 1 271 GLY 271 361 ?   ?   ?   D . n 
D 1 272 SER 272 362 ?   ?   ?   D . n 
D 1 273 SER 273 363 ?   ?   ?   D . n 
D 1 274 GLY 274 364 ?   ?   ?   D . n 
D 1 275 GLY 275 365 ?   ?   ?   D . n 
D 1 276 GLY 276 366 ?   ?   ?   D . n 
D 1 277 SER 277 367 ?   ?   ?   D . n 
D 1 278 THR 278 368 ?   ?   ?   D . n 
D 1 279 TYR 279 369 ?   ?   ?   D . n 
D 1 280 LYS 280 370 ?   ?   ?   D . n 
D 1 281 LEU 281 371 ?   ?   ?   D . n 
D 1 282 ILE 282 372 ?   ?   ?   D . n 
D 1 283 LEU 283 373 ?   ?   ?   D . n 
D 1 284 ASN 284 374 ?   ?   ?   D . n 
D 1 285 GLY 285 375 ?   ?   ?   D . n 
D 1 286 LYS 286 376 ?   ?   ?   D . n 
D 1 287 THR 287 377 ?   ?   ?   D . n 
D 1 288 LEU 288 378 ?   ?   ?   D . n 
D 1 289 LYS 289 379 ?   ?   ?   D . n 
D 1 290 GLY 290 380 ?   ?   ?   D . n 
D 1 291 GLU 291 381 ?   ?   ?   D . n 
D 1 292 THR 292 382 ?   ?   ?   D . n 
D 1 293 THR 293 383 ?   ?   ?   D . n 
D 1 294 THR 294 384 ?   ?   ?   D . n 
D 1 295 GLU 295 385 ?   ?   ?   D . n 
D 1 296 ALA 296 386 ?   ?   ?   D . n 
D 1 297 VAL 297 387 ?   ?   ?   D . n 
D 1 298 ASP 298 388 ?   ?   ?   D . n 
D 1 299 ALA 299 389 ?   ?   ?   D . n 
D 1 300 ALA 300 390 ?   ?   ?   D . n 
D 1 301 THR 301 391 ?   ?   ?   D . n 
D 1 302 ALA 302 392 ?   ?   ?   D . n 
D 1 303 GLU 303 393 ?   ?   ?   D . n 
D 1 304 LYS 304 394 ?   ?   ?   D . n 
D 1 305 VAL 305 395 ?   ?   ?   D . n 
D 1 306 PHE 306 396 ?   ?   ?   D . n 
D 1 307 LYS 307 397 ?   ?   ?   D . n 
D 1 308 GLN 308 398 ?   ?   ?   D . n 
D 1 309 TYR 309 399 ?   ?   ?   D . n 
D 1 310 ALA 310 400 ?   ?   ?   D . n 
D 1 311 ASN 311 401 ?   ?   ?   D . n 
D 1 312 ASP 312 402 ?   ?   ?   D . n 
D 1 313 ASN 313 403 ?   ?   ?   D . n 
D 1 314 GLY 314 404 ?   ?   ?   D . n 
D 1 315 VAL 315 405 ?   ?   ?   D . n 
D 1 316 ASP 316 406 ?   ?   ?   D . n 
D 1 317 GLY 317 407 ?   ?   ?   D . n 
D 1 318 GLU 318 408 ?   ?   ?   D . n 
D 1 319 TRP 319 409 ?   ?   ?   D . n 
D 1 320 THR 320 410 ?   ?   ?   D . n 
D 1 321 TYR 321 411 ?   ?   ?   D . n 
D 1 322 ASP 322 412 ?   ?   ?   D . n 
D 1 323 ASP 323 413 ?   ?   ?   D . n 
D 1 324 ALA 324 414 ?   ?   ?   D . n 
D 1 325 THR 325 415 ?   ?   ?   D . n 
D 1 326 LYS 326 416 ?   ?   ?   D . n 
D 1 327 THR 327 417 ?   ?   ?   D . n 
D 1 328 PHE 328 418 ?   ?   ?   D . n 
D 1 329 THR 329 419 ?   ?   ?   D . n 
D 1 330 VAL 330 420 ?   ?   ?   D . n 
D 1 331 THR 331 421 ?   ?   ?   D . n 
D 1 332 GLU 332 422 ?   ?   ?   D . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JA6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JA6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JA6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9JA6 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.007 ? 5332 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.811 ? 7188 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.076 ? 708  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 748  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 948  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JA6 
_struct.title                        'Cryo-EM structure of Tdk1 tetramer complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JA6 
_struct_keywords.text            'signaling protein, meiotic cell cycle, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP MU135_SCHPO O74876 ? 1 
;MSEEDNRLNELFANDLGVQPPCERSLKEGRRFLNDFEIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDND
ECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFRREMGEWKKAREEDK
;
1   
2 UNP MU135_SCHPO O74876 ? 1 
;EWRKSTDERLENLLNIVREILDVQRDMRNDLSNLTRKVDRMDMRLSRNNNMIMRSFAQPITEVPFFNGDIPDPNLPRITR
IEDIDSLSEENCTRYLKGYGVSYDENDQSLWKRQLAKAVGLTAAYDESYTFSPFSSSE
;
220 
3 UNP SPG1_STRSG  P06654 ? 1 TYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTE 228 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1  1 9JA6 A 1   ? 129 ? O74876 1   ? 129 ? 91  219 
2  2 9JA6 A 130 ? 267 ? O74876 220 ? 357 ? 220 357 
3  3 9JA6 A 278 ? 332 ? P06654 228 ? 282 ? 368 422 
4  1 9JA6 B 1   ? 129 ? O74876 1   ? 129 ? 91  219 
5  2 9JA6 B 130 ? 267 ? O74876 220 ? 357 ? 220 357 
6  3 9JA6 B 278 ? 332 ? P06654 228 ? 282 ? 368 422 
7  1 9JA6 C 1   ? 129 ? O74876 1   ? 129 ? 91  219 
8  2 9JA6 C 130 ? 267 ? O74876 220 ? 357 ? 220 357 
9  3 9JA6 C 278 ? 332 ? P06654 228 ? 282 ? 368 422 
10 1 9JA6 D 1   ? 129 ? O74876 1   ? 129 ? 91  219 
11 2 9JA6 D 130 ? 267 ? O74876 220 ? 357 ? 220 357 
12 3 9JA6 D 278 ? 332 ? P06654 228 ? 282 ? 368 422 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2  9JA6 ARG A 186 ? UNP O74876 ALA 276 conflict 276 1  
2  9JA6 ALA A 256 ? UNP O74876 GLU 346 conflict 346 2  
2  9JA6 SER A 268 ? UNP O74876 ?   ?   linker   358 3  
2  9JA6 GLY A 269 ? UNP O74876 ?   ?   linker   359 4  
2  9JA6 GLY A 270 ? UNP O74876 ?   ?   linker   360 5  
2  9JA6 GLY A 271 ? UNP O74876 ?   ?   linker   361 6  
2  9JA6 SER A 272 ? UNP O74876 ?   ?   linker   362 7  
2  9JA6 SER A 273 ? UNP O74876 ?   ?   linker   363 8  
2  9JA6 GLY A 274 ? UNP O74876 ?   ?   linker   364 9  
2  9JA6 GLY A 275 ? UNP O74876 ?   ?   linker   365 10 
2  9JA6 GLY A 276 ? UNP O74876 ?   ?   linker   366 11 
2  9JA6 SER A 277 ? UNP O74876 ?   ?   linker   367 12 
5  9JA6 ARG B 186 ? UNP O74876 ALA 276 conflict 276 13 
5  9JA6 ALA B 256 ? UNP O74876 GLU 346 conflict 346 14 
5  9JA6 SER B 268 ? UNP O74876 ?   ?   linker   358 15 
5  9JA6 GLY B 269 ? UNP O74876 ?   ?   linker   359 16 
5  9JA6 GLY B 270 ? UNP O74876 ?   ?   linker   360 17 
5  9JA6 GLY B 271 ? UNP O74876 ?   ?   linker   361 18 
5  9JA6 SER B 272 ? UNP O74876 ?   ?   linker   362 19 
5  9JA6 SER B 273 ? UNP O74876 ?   ?   linker   363 20 
5  9JA6 GLY B 274 ? UNP O74876 ?   ?   linker   364 21 
5  9JA6 GLY B 275 ? UNP O74876 ?   ?   linker   365 22 
5  9JA6 GLY B 276 ? UNP O74876 ?   ?   linker   366 23 
5  9JA6 SER B 277 ? UNP O74876 ?   ?   linker   367 24 
8  9JA6 ARG C 186 ? UNP O74876 ALA 276 conflict 276 25 
8  9JA6 ALA C 256 ? UNP O74876 GLU 346 conflict 346 26 
8  9JA6 SER C 268 ? UNP O74876 ?   ?   linker   358 27 
8  9JA6 GLY C 269 ? UNP O74876 ?   ?   linker   359 28 
8  9JA6 GLY C 270 ? UNP O74876 ?   ?   linker   360 29 
8  9JA6 GLY C 271 ? UNP O74876 ?   ?   linker   361 30 
8  9JA6 SER C 272 ? UNP O74876 ?   ?   linker   362 31 
8  9JA6 SER C 273 ? UNP O74876 ?   ?   linker   363 32 
8  9JA6 GLY C 274 ? UNP O74876 ?   ?   linker   364 33 
8  9JA6 GLY C 275 ? UNP O74876 ?   ?   linker   365 34 
8  9JA6 GLY C 276 ? UNP O74876 ?   ?   linker   366 35 
8  9JA6 SER C 277 ? UNP O74876 ?   ?   linker   367 36 
11 9JA6 ARG D 186 ? UNP O74876 ALA 276 conflict 276 37 
11 9JA6 ALA D 256 ? UNP O74876 GLU 346 conflict 346 38 
11 9JA6 SER D 268 ? UNP O74876 ?   ?   linker   358 39 
11 9JA6 GLY D 269 ? UNP O74876 ?   ?   linker   359 40 
11 9JA6 GLY D 270 ? UNP O74876 ?   ?   linker   360 41 
11 9JA6 GLY D 271 ? UNP O74876 ?   ?   linker   361 42 
11 9JA6 SER D 272 ? UNP O74876 ?   ?   linker   362 43 
11 9JA6 SER D 273 ? UNP O74876 ?   ?   linker   363 44 
11 9JA6 GLY D 274 ? UNP O74876 ?   ?   linker   364 45 
11 9JA6 GLY D 275 ? UNP O74876 ?   ?   linker   365 46 
11 9JA6 GLY D 276 ? UNP O74876 ?   ?   linker   366 47 
11 9JA6 SER D 277 ? UNP O74876 ?   ?   linker   367 48 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 118 ? SER A 184 ? MET A 208 SER A 274 1 ? 67 
HELX_P HELX_P2  AA2 ARG A 209 ? SER A 215 ? ARG A 299 SER A 305 1 ? 7  
HELX_P HELX_P3  AA3 SER A 217 ? TYR A 228 ? SER A 307 TYR A 318 1 ? 12 
HELX_P HELX_P4  AA4 ASP A 236 ? SER A 238 ? ASP A 326 SER A 328 5 ? 3  
HELX_P HELX_P5  AA5 LEU A 239 ? GLY A 249 ? LEU A 329 GLY A 339 1 ? 11 
HELX_P HELX_P6  AA6 ALA A 252 ? TYR A 258 ? ALA A 342 TYR A 348 1 ? 7  
HELX_P HELX_P7  AA7 GLY B 119 ? SER B 184 ? GLY B 209 SER B 274 1 ? 66 
HELX_P HELX_P8  AA8 ARG B 209 ? SER B 215 ? ARG B 299 SER B 305 1 ? 7  
HELX_P HELX_P9  AA9 SER B 217 ? TYR B 228 ? SER B 307 TYR B 318 1 ? 12 
HELX_P HELX_P10 AB1 ASP B 236 ? SER B 238 ? ASP B 326 SER B 328 5 ? 3  
HELX_P HELX_P11 AB2 LEU B 239 ? GLY B 249 ? LEU B 329 GLY B 339 1 ? 11 
HELX_P HELX_P12 AB3 ALA B 252 ? TYR B 258 ? ALA B 342 TYR B 348 1 ? 7  
HELX_P HELX_P13 AB4 GLY C 119 ? SER C 184 ? GLY C 209 SER C 274 1 ? 66 
HELX_P HELX_P14 AB5 ARG C 209 ? SER C 215 ? ARG C 299 SER C 305 1 ? 7  
HELX_P HELX_P15 AB6 SER C 217 ? TYR C 228 ? SER C 307 TYR C 318 1 ? 12 
HELX_P HELX_P16 AB7 ASP C 236 ? SER C 238 ? ASP C 326 SER C 328 5 ? 3  
HELX_P HELX_P17 AB8 LEU C 239 ? GLY C 249 ? LEU C 329 GLY C 339 1 ? 11 
HELX_P HELX_P18 AB9 ALA C 252 ? TYR C 258 ? ALA C 342 TYR C 348 1 ? 7  
HELX_P HELX_P19 AC1 GLY D 119 ? SER D 184 ? GLY D 209 SER D 274 1 ? 66 
HELX_P HELX_P20 AC2 ARG D 209 ? SER D 215 ? ARG D 299 SER D 305 1 ? 7  
HELX_P HELX_P21 AC3 SER D 217 ? TYR D 228 ? SER D 307 TYR D 318 1 ? 12 
HELX_P HELX_P22 AC4 ASP D 236 ? SER D 238 ? ASP D 326 SER D 328 5 ? 3  
HELX_P HELX_P23 AC5 LEU D 239 ? GLY D 249 ? LEU D 329 GLY D 339 1 ? 11 
HELX_P HELX_P24 AC6 ALA D 252 ? TYR D 258 ? ALA D 342 TYR D 348 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9JA6 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PRO A 290 ? ? -57.35 172.47 
2 1 LEU A 340 ? ? -67.87 98.28  
3 1 PRO B 290 ? ? -57.21 172.40 
4 1 LEU B 340 ? ? -67.86 98.36  
5 1 PRO C 290 ? ? -57.29 172.45 
6 1 LEU C 340 ? ? -67.93 98.36  
7 1 PRO D 290 ? ? -57.28 172.44 
8 1 LEU D 340 ? ? -67.93 98.34  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JA6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'Correlation coefficient' 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'AB INITIO MODEL' 
# 
_em_3d_reconstruction.entry_id                    9JA6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  4.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               37724 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Tdk1 tetramer' 
_em_entity_assembly.details              
;The fusion protein comprises of residues 1-129 and 220-357 of Tdk1, mutations A276R and E346A, a linker sequence(SGGGSSGGGS), and residues 228-282 of Immunoglobulin G-binding protein G(GB1).
;
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                9JA6 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        32 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9JA6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        Homemade 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9JA6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               'blot for 5 seconds before plunging' 
# 
_em_experiment.entry_id                9JA6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 91  ? A MET 1   
2   1 Y 1 A SER 92  ? A SER 2   
3   1 Y 1 A GLU 93  ? A GLU 3   
4   1 Y 1 A GLU 94  ? A GLU 4   
5   1 Y 1 A ASP 95  ? A ASP 5   
6   1 Y 1 A ASN 96  ? A ASN 6   
7   1 Y 1 A ARG 97  ? A ARG 7   
8   1 Y 1 A LEU 98  ? A LEU 8   
9   1 Y 1 A ASN 99  ? A ASN 9   
10  1 Y 1 A GLU 100 ? A GLU 10  
11  1 Y 1 A LEU 101 ? A LEU 11  
12  1 Y 1 A PHE 102 ? A PHE 12  
13  1 Y 1 A ALA 103 ? A ALA 13  
14  1 Y 1 A ASN 104 ? A ASN 14  
15  1 Y 1 A ASP 105 ? A ASP 15  
16  1 Y 1 A LEU 106 ? A LEU 16  
17  1 Y 1 A GLY 107 ? A GLY 17  
18  1 Y 1 A VAL 108 ? A VAL 18  
19  1 Y 1 A GLN 109 ? A GLN 19  
20  1 Y 1 A PRO 110 ? A PRO 20  
21  1 Y 1 A PRO 111 ? A PRO 21  
22  1 Y 1 A CYS 112 ? A CYS 22  
23  1 Y 1 A GLU 113 ? A GLU 23  
24  1 Y 1 A ARG 114 ? A ARG 24  
25  1 Y 1 A SER 115 ? A SER 25  
26  1 Y 1 A LEU 116 ? A LEU 26  
27  1 Y 1 A LYS 117 ? A LYS 27  
28  1 Y 1 A GLU 118 ? A GLU 28  
29  1 Y 1 A GLY 119 ? A GLY 29  
30  1 Y 1 A ARG 120 ? A ARG 30  
31  1 Y 1 A ARG 121 ? A ARG 31  
32  1 Y 1 A PHE 122 ? A PHE 32  
33  1 Y 1 A LEU 123 ? A LEU 33  
34  1 Y 1 A ASN 124 ? A ASN 34  
35  1 Y 1 A ASP 125 ? A ASP 35  
36  1 Y 1 A PHE 126 ? A PHE 36  
37  1 Y 1 A GLU 127 ? A GLU 37  
38  1 Y 1 A ILE 128 ? A ILE 38  
39  1 Y 1 A ALA 129 ? A ALA 39  
40  1 Y 1 A ALA 130 ? A ALA 40  
41  1 Y 1 A LYS 131 ? A LYS 41  
42  1 Y 1 A LYS 132 ? A LYS 42  
43  1 Y 1 A LYS 133 ? A LYS 43  
44  1 Y 1 A LEU 134 ? A LEU 44  
45  1 Y 1 A LEU 135 ? A LEU 45  
46  1 Y 1 A GLU 136 ? A GLU 46  
47  1 Y 1 A LEU 137 ? A LEU 47  
48  1 Y 1 A GLU 138 ? A GLU 48  
49  1 Y 1 A ARG 139 ? A ARG 49  
50  1 Y 1 A LYS 140 ? A LYS 50  
51  1 Y 1 A ALA 141 ? A ALA 51  
52  1 Y 1 A LEU 142 ? A LEU 52  
53  1 Y 1 A GLU 143 ? A GLU 53  
54  1 Y 1 A ASP 144 ? A ASP 54  
55  1 Y 1 A LYS 145 ? A LYS 55  
56  1 Y 1 A GLU 146 ? A GLU 56  
57  1 Y 1 A LYS 147 ? A LYS 57  
58  1 Y 1 A ASN 148 ? A ASN 58  
59  1 Y 1 A LEU 149 ? A LEU 59  
60  1 Y 1 A ASN 150 ? A ASN 60  
61  1 Y 1 A PHE 151 ? A PHE 61  
62  1 Y 1 A VAL 152 ? A VAL 62  
63  1 Y 1 A VAL 153 ? A VAL 63  
64  1 Y 1 A GLU 154 ? A GLU 64  
65  1 Y 1 A SER 155 ? A SER 65  
66  1 Y 1 A GLU 156 ? A GLU 66  
67  1 Y 1 A ARG 157 ? A ARG 67  
68  1 Y 1 A THR 158 ? A THR 68  
69  1 Y 1 A LEU 159 ? A LEU 69  
70  1 Y 1 A PHE 160 ? A PHE 70  
71  1 Y 1 A ASN 161 ? A ASN 71  
72  1 Y 1 A SER 162 ? A SER 72  
73  1 Y 1 A LYS 163 ? A LYS 73  
74  1 Y 1 A LYS 164 ? A LYS 74  
75  1 Y 1 A ARG 165 ? A ARG 75  
76  1 Y 1 A ALA 166 ? A ALA 76  
77  1 Y 1 A PHE 167 ? A PHE 77  
78  1 Y 1 A ASP 168 ? A ASP 78  
79  1 Y 1 A ASN 169 ? A ASN 79  
80  1 Y 1 A ASP 170 ? A ASP 80  
81  1 Y 1 A GLU 171 ? A GLU 81  
82  1 Y 1 A CYS 172 ? A CYS 82  
83  1 Y 1 A TYR 173 ? A TYR 83  
84  1 Y 1 A ASN 174 ? A ASN 84  
85  1 Y 1 A ASP 175 ? A ASP 85  
86  1 Y 1 A ARG 176 ? A ARG 86  
87  1 Y 1 A CYS 177 ? A CYS 87  
88  1 Y 1 A LYS 178 ? A LYS 88  
89  1 Y 1 A LEU 179 ? A LEU 89  
90  1 Y 1 A PHE 180 ? A PHE 90  
91  1 Y 1 A ARG 181 ? A ARG 91  
92  1 Y 1 A GLY 182 ? A GLY 92  
93  1 Y 1 A ILE 183 ? A ILE 93  
94  1 Y 1 A VAL 184 ? A VAL 94  
95  1 Y 1 A ASN 185 ? A ASN 95  
96  1 Y 1 A GLU 186 ? A GLU 96  
97  1 Y 1 A TRP 187 ? A TRP 97  
98  1 Y 1 A GLY 188 ? A GLY 98  
99  1 Y 1 A ARG 189 ? A ARG 99  
100 1 Y 1 A SER 190 ? A SER 100 
101 1 Y 1 A GLU 191 ? A GLU 101 
102 1 Y 1 A ARG 192 ? A ARG 102 
103 1 Y 1 A THR 193 ? A THR 103 
104 1 Y 1 A LEU 194 ? A LEU 104 
105 1 Y 1 A ASP 195 ? A ASP 105 
106 1 Y 1 A SER 196 ? A SER 106 
107 1 Y 1 A LEU 197 ? A LEU 107 
108 1 Y 1 A ASP 198 ? A ASP 108 
109 1 Y 1 A GLU 199 ? A GLU 109 
110 1 Y 1 A PRO 200 ? A PRO 110 
111 1 Y 1 A PRO 201 ? A PRO 111 
112 1 Y 1 A ALA 202 ? A ALA 112 
113 1 Y 1 A TRP 203 ? A TRP 113 
114 1 Y 1 A PHE 204 ? A PHE 114 
115 1 Y 1 A ARG 205 ? A ARG 115 
116 1 Y 1 A ARG 206 ? A ARG 116 
117 1 Y 1 A GLU 207 ? A GLU 117 
118 1 Y 1 A SER 355 ? A SER 265 
119 1 Y 1 A SER 356 ? A SER 266 
120 1 Y 1 A GLU 357 ? A GLU 267 
121 1 Y 1 A SER 358 ? A SER 268 
122 1 Y 1 A GLY 359 ? A GLY 269 
123 1 Y 1 A GLY 360 ? A GLY 270 
124 1 Y 1 A GLY 361 ? A GLY 271 
125 1 Y 1 A SER 362 ? A SER 272 
126 1 Y 1 A SER 363 ? A SER 273 
127 1 Y 1 A GLY 364 ? A GLY 274 
128 1 Y 1 A GLY 365 ? A GLY 275 
129 1 Y 1 A GLY 366 ? A GLY 276 
130 1 Y 1 A SER 367 ? A SER 277 
131 1 Y 1 A THR 368 ? A THR 278 
132 1 Y 1 A TYR 369 ? A TYR 279 
133 1 Y 1 A LYS 370 ? A LYS 280 
134 1 Y 1 A LEU 371 ? A LEU 281 
135 1 Y 1 A ILE 372 ? A ILE 282 
136 1 Y 1 A LEU 373 ? A LEU 283 
137 1 Y 1 A ASN 374 ? A ASN 284 
138 1 Y 1 A GLY 375 ? A GLY 285 
139 1 Y 1 A LYS 376 ? A LYS 286 
140 1 Y 1 A THR 377 ? A THR 287 
141 1 Y 1 A LEU 378 ? A LEU 288 
142 1 Y 1 A LYS 379 ? A LYS 289 
143 1 Y 1 A GLY 380 ? A GLY 290 
144 1 Y 1 A GLU 381 ? A GLU 291 
145 1 Y 1 A THR 382 ? A THR 292 
146 1 Y 1 A THR 383 ? A THR 293 
147 1 Y 1 A THR 384 ? A THR 294 
148 1 Y 1 A GLU 385 ? A GLU 295 
149 1 Y 1 A ALA 386 ? A ALA 296 
150 1 Y 1 A VAL 387 ? A VAL 297 
151 1 Y 1 A ASP 388 ? A ASP 298 
152 1 Y 1 A ALA 389 ? A ALA 299 
153 1 Y 1 A ALA 390 ? A ALA 300 
154 1 Y 1 A THR 391 ? A THR 301 
155 1 Y 1 A ALA 392 ? A ALA 302 
156 1 Y 1 A GLU 393 ? A GLU 303 
157 1 Y 1 A LYS 394 ? A LYS 304 
158 1 Y 1 A VAL 395 ? A VAL 305 
159 1 Y 1 A PHE 396 ? A PHE 306 
160 1 Y 1 A LYS 397 ? A LYS 307 
161 1 Y 1 A GLN 398 ? A GLN 308 
162 1 Y 1 A TYR 399 ? A TYR 309 
163 1 Y 1 A ALA 400 ? A ALA 310 
164 1 Y 1 A ASN 401 ? A ASN 311 
165 1 Y 1 A ASP 402 ? A ASP 312 
166 1 Y 1 A ASN 403 ? A ASN 313 
167 1 Y 1 A GLY 404 ? A GLY 314 
168 1 Y 1 A VAL 405 ? A VAL 315 
169 1 Y 1 A ASP 406 ? A ASP 316 
170 1 Y 1 A GLY 407 ? A GLY 317 
171 1 Y 1 A GLU 408 ? A GLU 318 
172 1 Y 1 A TRP 409 ? A TRP 319 
173 1 Y 1 A THR 410 ? A THR 320 
174 1 Y 1 A TYR 411 ? A TYR 321 
175 1 Y 1 A ASP 412 ? A ASP 322 
176 1 Y 1 A ASP 413 ? A ASP 323 
177 1 Y 1 A ALA 414 ? A ALA 324 
178 1 Y 1 A THR 415 ? A THR 325 
179 1 Y 1 A LYS 416 ? A LYS 326 
180 1 Y 1 A THR 417 ? A THR 327 
181 1 Y 1 A PHE 418 ? A PHE 328 
182 1 Y 1 A THR 419 ? A THR 329 
183 1 Y 1 A VAL 420 ? A VAL 330 
184 1 Y 1 A THR 421 ? A THR 331 
185 1 Y 1 A GLU 422 ? A GLU 332 
186 1 Y 1 B MET 91  ? B MET 1   
187 1 Y 1 B SER 92  ? B SER 2   
188 1 Y 1 B GLU 93  ? B GLU 3   
189 1 Y 1 B GLU 94  ? B GLU 4   
190 1 Y 1 B ASP 95  ? B ASP 5   
191 1 Y 1 B ASN 96  ? B ASN 6   
192 1 Y 1 B ARG 97  ? B ARG 7   
193 1 Y 1 B LEU 98  ? B LEU 8   
194 1 Y 1 B ASN 99  ? B ASN 9   
195 1 Y 1 B GLU 100 ? B GLU 10  
196 1 Y 1 B LEU 101 ? B LEU 11  
197 1 Y 1 B PHE 102 ? B PHE 12  
198 1 Y 1 B ALA 103 ? B ALA 13  
199 1 Y 1 B ASN 104 ? B ASN 14  
200 1 Y 1 B ASP 105 ? B ASP 15  
201 1 Y 1 B LEU 106 ? B LEU 16  
202 1 Y 1 B GLY 107 ? B GLY 17  
203 1 Y 1 B VAL 108 ? B VAL 18  
204 1 Y 1 B GLN 109 ? B GLN 19  
205 1 Y 1 B PRO 110 ? B PRO 20  
206 1 Y 1 B PRO 111 ? B PRO 21  
207 1 Y 1 B CYS 112 ? B CYS 22  
208 1 Y 1 B GLU 113 ? B GLU 23  
209 1 Y 1 B ARG 114 ? B ARG 24  
210 1 Y 1 B SER 115 ? B SER 25  
211 1 Y 1 B LEU 116 ? B LEU 26  
212 1 Y 1 B LYS 117 ? B LYS 27  
213 1 Y 1 B GLU 118 ? B GLU 28  
214 1 Y 1 B GLY 119 ? B GLY 29  
215 1 Y 1 B ARG 120 ? B ARG 30  
216 1 Y 1 B ARG 121 ? B ARG 31  
217 1 Y 1 B PHE 122 ? B PHE 32  
218 1 Y 1 B LEU 123 ? B LEU 33  
219 1 Y 1 B ASN 124 ? B ASN 34  
220 1 Y 1 B ASP 125 ? B ASP 35  
221 1 Y 1 B PHE 126 ? B PHE 36  
222 1 Y 1 B GLU 127 ? B GLU 37  
223 1 Y 1 B ILE 128 ? B ILE 38  
224 1 Y 1 B ALA 129 ? B ALA 39  
225 1 Y 1 B ALA 130 ? B ALA 40  
226 1 Y 1 B LYS 131 ? B LYS 41  
227 1 Y 1 B LYS 132 ? B LYS 42  
228 1 Y 1 B LYS 133 ? B LYS 43  
229 1 Y 1 B LEU 134 ? B LEU 44  
230 1 Y 1 B LEU 135 ? B LEU 45  
231 1 Y 1 B GLU 136 ? B GLU 46  
232 1 Y 1 B LEU 137 ? B LEU 47  
233 1 Y 1 B GLU 138 ? B GLU 48  
234 1 Y 1 B ARG 139 ? B ARG 49  
235 1 Y 1 B LYS 140 ? B LYS 50  
236 1 Y 1 B ALA 141 ? B ALA 51  
237 1 Y 1 B LEU 142 ? B LEU 52  
238 1 Y 1 B GLU 143 ? B GLU 53  
239 1 Y 1 B ASP 144 ? B ASP 54  
240 1 Y 1 B LYS 145 ? B LYS 55  
241 1 Y 1 B GLU 146 ? B GLU 56  
242 1 Y 1 B LYS 147 ? B LYS 57  
243 1 Y 1 B ASN 148 ? B ASN 58  
244 1 Y 1 B LEU 149 ? B LEU 59  
245 1 Y 1 B ASN 150 ? B ASN 60  
246 1 Y 1 B PHE 151 ? B PHE 61  
247 1 Y 1 B VAL 152 ? B VAL 62  
248 1 Y 1 B VAL 153 ? B VAL 63  
249 1 Y 1 B GLU 154 ? B GLU 64  
250 1 Y 1 B SER 155 ? B SER 65  
251 1 Y 1 B GLU 156 ? B GLU 66  
252 1 Y 1 B ARG 157 ? B ARG 67  
253 1 Y 1 B THR 158 ? B THR 68  
254 1 Y 1 B LEU 159 ? B LEU 69  
255 1 Y 1 B PHE 160 ? B PHE 70  
256 1 Y 1 B ASN 161 ? B ASN 71  
257 1 Y 1 B SER 162 ? B SER 72  
258 1 Y 1 B LYS 163 ? B LYS 73  
259 1 Y 1 B LYS 164 ? B LYS 74  
260 1 Y 1 B ARG 165 ? B ARG 75  
261 1 Y 1 B ALA 166 ? B ALA 76  
262 1 Y 1 B PHE 167 ? B PHE 77  
263 1 Y 1 B ASP 168 ? B ASP 78  
264 1 Y 1 B ASN 169 ? B ASN 79  
265 1 Y 1 B ASP 170 ? B ASP 80  
266 1 Y 1 B GLU 171 ? B GLU 81  
267 1 Y 1 B CYS 172 ? B CYS 82  
268 1 Y 1 B TYR 173 ? B TYR 83  
269 1 Y 1 B ASN 174 ? B ASN 84  
270 1 Y 1 B ASP 175 ? B ASP 85  
271 1 Y 1 B ARG 176 ? B ARG 86  
272 1 Y 1 B CYS 177 ? B CYS 87  
273 1 Y 1 B LYS 178 ? B LYS 88  
274 1 Y 1 B LEU 179 ? B LEU 89  
275 1 Y 1 B PHE 180 ? B PHE 90  
276 1 Y 1 B ARG 181 ? B ARG 91  
277 1 Y 1 B GLY 182 ? B GLY 92  
278 1 Y 1 B ILE 183 ? B ILE 93  
279 1 Y 1 B VAL 184 ? B VAL 94  
280 1 Y 1 B ASN 185 ? B ASN 95  
281 1 Y 1 B GLU 186 ? B GLU 96  
282 1 Y 1 B TRP 187 ? B TRP 97  
283 1 Y 1 B GLY 188 ? B GLY 98  
284 1 Y 1 B ARG 189 ? B ARG 99  
285 1 Y 1 B SER 190 ? B SER 100 
286 1 Y 1 B GLU 191 ? B GLU 101 
287 1 Y 1 B ARG 192 ? B ARG 102 
288 1 Y 1 B THR 193 ? B THR 103 
289 1 Y 1 B LEU 194 ? B LEU 104 
290 1 Y 1 B ASP 195 ? B ASP 105 
291 1 Y 1 B SER 196 ? B SER 106 
292 1 Y 1 B LEU 197 ? B LEU 107 
293 1 Y 1 B ASP 198 ? B ASP 108 
294 1 Y 1 B GLU 199 ? B GLU 109 
295 1 Y 1 B PRO 200 ? B PRO 110 
296 1 Y 1 B PRO 201 ? B PRO 111 
297 1 Y 1 B ALA 202 ? B ALA 112 
298 1 Y 1 B TRP 203 ? B TRP 113 
299 1 Y 1 B PHE 204 ? B PHE 114 
300 1 Y 1 B ARG 205 ? B ARG 115 
301 1 Y 1 B ARG 206 ? B ARG 116 
302 1 Y 1 B GLU 207 ? B GLU 117 
303 1 Y 1 B SER 355 ? B SER 265 
304 1 Y 1 B SER 356 ? B SER 266 
305 1 Y 1 B GLU 357 ? B GLU 267 
306 1 Y 1 B SER 358 ? B SER 268 
307 1 Y 1 B GLY 359 ? B GLY 269 
308 1 Y 1 B GLY 360 ? B GLY 270 
309 1 Y 1 B GLY 361 ? B GLY 271 
310 1 Y 1 B SER 362 ? B SER 272 
311 1 Y 1 B SER 363 ? B SER 273 
312 1 Y 1 B GLY 364 ? B GLY 274 
313 1 Y 1 B GLY 365 ? B GLY 275 
314 1 Y 1 B GLY 366 ? B GLY 276 
315 1 Y 1 B SER 367 ? B SER 277 
316 1 Y 1 B THR 368 ? B THR 278 
317 1 Y 1 B TYR 369 ? B TYR 279 
318 1 Y 1 B LYS 370 ? B LYS 280 
319 1 Y 1 B LEU 371 ? B LEU 281 
320 1 Y 1 B ILE 372 ? B ILE 282 
321 1 Y 1 B LEU 373 ? B LEU 283 
322 1 Y 1 B ASN 374 ? B ASN 284 
323 1 Y 1 B GLY 375 ? B GLY 285 
324 1 Y 1 B LYS 376 ? B LYS 286 
325 1 Y 1 B THR 377 ? B THR 287 
326 1 Y 1 B LEU 378 ? B LEU 288 
327 1 Y 1 B LYS 379 ? B LYS 289 
328 1 Y 1 B GLY 380 ? B GLY 290 
329 1 Y 1 B GLU 381 ? B GLU 291 
330 1 Y 1 B THR 382 ? B THR 292 
331 1 Y 1 B THR 383 ? B THR 293 
332 1 Y 1 B THR 384 ? B THR 294 
333 1 Y 1 B GLU 385 ? B GLU 295 
334 1 Y 1 B ALA 386 ? B ALA 296 
335 1 Y 1 B VAL 387 ? B VAL 297 
336 1 Y 1 B ASP 388 ? B ASP 298 
337 1 Y 1 B ALA 389 ? B ALA 299 
338 1 Y 1 B ALA 390 ? B ALA 300 
339 1 Y 1 B THR 391 ? B THR 301 
340 1 Y 1 B ALA 392 ? B ALA 302 
341 1 Y 1 B GLU 393 ? B GLU 303 
342 1 Y 1 B LYS 394 ? B LYS 304 
343 1 Y 1 B VAL 395 ? B VAL 305 
344 1 Y 1 B PHE 396 ? B PHE 306 
345 1 Y 1 B LYS 397 ? B LYS 307 
346 1 Y 1 B GLN 398 ? B GLN 308 
347 1 Y 1 B TYR 399 ? B TYR 309 
348 1 Y 1 B ALA 400 ? B ALA 310 
349 1 Y 1 B ASN 401 ? B ASN 311 
350 1 Y 1 B ASP 402 ? B ASP 312 
351 1 Y 1 B ASN 403 ? B ASN 313 
352 1 Y 1 B GLY 404 ? B GLY 314 
353 1 Y 1 B VAL 405 ? B VAL 315 
354 1 Y 1 B ASP 406 ? B ASP 316 
355 1 Y 1 B GLY 407 ? B GLY 317 
356 1 Y 1 B GLU 408 ? B GLU 318 
357 1 Y 1 B TRP 409 ? B TRP 319 
358 1 Y 1 B THR 410 ? B THR 320 
359 1 Y 1 B TYR 411 ? B TYR 321 
360 1 Y 1 B ASP 412 ? B ASP 322 
361 1 Y 1 B ASP 413 ? B ASP 323 
362 1 Y 1 B ALA 414 ? B ALA 324 
363 1 Y 1 B THR 415 ? B THR 325 
364 1 Y 1 B LYS 416 ? B LYS 326 
365 1 Y 1 B THR 417 ? B THR 327 
366 1 Y 1 B PHE 418 ? B PHE 328 
367 1 Y 1 B THR 419 ? B THR 329 
368 1 Y 1 B VAL 420 ? B VAL 330 
369 1 Y 1 B THR 421 ? B THR 331 
370 1 Y 1 B GLU 422 ? B GLU 332 
371 1 Y 1 C MET 91  ? C MET 1   
372 1 Y 1 C SER 92  ? C SER 2   
373 1 Y 1 C GLU 93  ? C GLU 3   
374 1 Y 1 C GLU 94  ? C GLU 4   
375 1 Y 1 C ASP 95  ? C ASP 5   
376 1 Y 1 C ASN 96  ? C ASN 6   
377 1 Y 1 C ARG 97  ? C ARG 7   
378 1 Y 1 C LEU 98  ? C LEU 8   
379 1 Y 1 C ASN 99  ? C ASN 9   
380 1 Y 1 C GLU 100 ? C GLU 10  
381 1 Y 1 C LEU 101 ? C LEU 11  
382 1 Y 1 C PHE 102 ? C PHE 12  
383 1 Y 1 C ALA 103 ? C ALA 13  
384 1 Y 1 C ASN 104 ? C ASN 14  
385 1 Y 1 C ASP 105 ? C ASP 15  
386 1 Y 1 C LEU 106 ? C LEU 16  
387 1 Y 1 C GLY 107 ? C GLY 17  
388 1 Y 1 C VAL 108 ? C VAL 18  
389 1 Y 1 C GLN 109 ? C GLN 19  
390 1 Y 1 C PRO 110 ? C PRO 20  
391 1 Y 1 C PRO 111 ? C PRO 21  
392 1 Y 1 C CYS 112 ? C CYS 22  
393 1 Y 1 C GLU 113 ? C GLU 23  
394 1 Y 1 C ARG 114 ? C ARG 24  
395 1 Y 1 C SER 115 ? C SER 25  
396 1 Y 1 C LEU 116 ? C LEU 26  
397 1 Y 1 C LYS 117 ? C LYS 27  
398 1 Y 1 C GLU 118 ? C GLU 28  
399 1 Y 1 C GLY 119 ? C GLY 29  
400 1 Y 1 C ARG 120 ? C ARG 30  
401 1 Y 1 C ARG 121 ? C ARG 31  
402 1 Y 1 C PHE 122 ? C PHE 32  
403 1 Y 1 C LEU 123 ? C LEU 33  
404 1 Y 1 C ASN 124 ? C ASN 34  
405 1 Y 1 C ASP 125 ? C ASP 35  
406 1 Y 1 C PHE 126 ? C PHE 36  
407 1 Y 1 C GLU 127 ? C GLU 37  
408 1 Y 1 C ILE 128 ? C ILE 38  
409 1 Y 1 C ALA 129 ? C ALA 39  
410 1 Y 1 C ALA 130 ? C ALA 40  
411 1 Y 1 C LYS 131 ? C LYS 41  
412 1 Y 1 C LYS 132 ? C LYS 42  
413 1 Y 1 C LYS 133 ? C LYS 43  
414 1 Y 1 C LEU 134 ? C LEU 44  
415 1 Y 1 C LEU 135 ? C LEU 45  
416 1 Y 1 C GLU 136 ? C GLU 46  
417 1 Y 1 C LEU 137 ? C LEU 47  
418 1 Y 1 C GLU 138 ? C GLU 48  
419 1 Y 1 C ARG 139 ? C ARG 49  
420 1 Y 1 C LYS 140 ? C LYS 50  
421 1 Y 1 C ALA 141 ? C ALA 51  
422 1 Y 1 C LEU 142 ? C LEU 52  
423 1 Y 1 C GLU 143 ? C GLU 53  
424 1 Y 1 C ASP 144 ? C ASP 54  
425 1 Y 1 C LYS 145 ? C LYS 55  
426 1 Y 1 C GLU 146 ? C GLU 56  
427 1 Y 1 C LYS 147 ? C LYS 57  
428 1 Y 1 C ASN 148 ? C ASN 58  
429 1 Y 1 C LEU 149 ? C LEU 59  
430 1 Y 1 C ASN 150 ? C ASN 60  
431 1 Y 1 C PHE 151 ? C PHE 61  
432 1 Y 1 C VAL 152 ? C VAL 62  
433 1 Y 1 C VAL 153 ? C VAL 63  
434 1 Y 1 C GLU 154 ? C GLU 64  
435 1 Y 1 C SER 155 ? C SER 65  
436 1 Y 1 C GLU 156 ? C GLU 66  
437 1 Y 1 C ARG 157 ? C ARG 67  
438 1 Y 1 C THR 158 ? C THR 68  
439 1 Y 1 C LEU 159 ? C LEU 69  
440 1 Y 1 C PHE 160 ? C PHE 70  
441 1 Y 1 C ASN 161 ? C ASN 71  
442 1 Y 1 C SER 162 ? C SER 72  
443 1 Y 1 C LYS 163 ? C LYS 73  
444 1 Y 1 C LYS 164 ? C LYS 74  
445 1 Y 1 C ARG 165 ? C ARG 75  
446 1 Y 1 C ALA 166 ? C ALA 76  
447 1 Y 1 C PHE 167 ? C PHE 77  
448 1 Y 1 C ASP 168 ? C ASP 78  
449 1 Y 1 C ASN 169 ? C ASN 79  
450 1 Y 1 C ASP 170 ? C ASP 80  
451 1 Y 1 C GLU 171 ? C GLU 81  
452 1 Y 1 C CYS 172 ? C CYS 82  
453 1 Y 1 C TYR 173 ? C TYR 83  
454 1 Y 1 C ASN 174 ? C ASN 84  
455 1 Y 1 C ASP 175 ? C ASP 85  
456 1 Y 1 C ARG 176 ? C ARG 86  
457 1 Y 1 C CYS 177 ? C CYS 87  
458 1 Y 1 C LYS 178 ? C LYS 88  
459 1 Y 1 C LEU 179 ? C LEU 89  
460 1 Y 1 C PHE 180 ? C PHE 90  
461 1 Y 1 C ARG 181 ? C ARG 91  
462 1 Y 1 C GLY 182 ? C GLY 92  
463 1 Y 1 C ILE 183 ? C ILE 93  
464 1 Y 1 C VAL 184 ? C VAL 94  
465 1 Y 1 C ASN 185 ? C ASN 95  
466 1 Y 1 C GLU 186 ? C GLU 96  
467 1 Y 1 C TRP 187 ? C TRP 97  
468 1 Y 1 C GLY 188 ? C GLY 98  
469 1 Y 1 C ARG 189 ? C ARG 99  
470 1 Y 1 C SER 190 ? C SER 100 
471 1 Y 1 C GLU 191 ? C GLU 101 
472 1 Y 1 C ARG 192 ? C ARG 102 
473 1 Y 1 C THR 193 ? C THR 103 
474 1 Y 1 C LEU 194 ? C LEU 104 
475 1 Y 1 C ASP 195 ? C ASP 105 
476 1 Y 1 C SER 196 ? C SER 106 
477 1 Y 1 C LEU 197 ? C LEU 107 
478 1 Y 1 C ASP 198 ? C ASP 108 
479 1 Y 1 C GLU 199 ? C GLU 109 
480 1 Y 1 C PRO 200 ? C PRO 110 
481 1 Y 1 C PRO 201 ? C PRO 111 
482 1 Y 1 C ALA 202 ? C ALA 112 
483 1 Y 1 C TRP 203 ? C TRP 113 
484 1 Y 1 C PHE 204 ? C PHE 114 
485 1 Y 1 C ARG 205 ? C ARG 115 
486 1 Y 1 C ARG 206 ? C ARG 116 
487 1 Y 1 C GLU 207 ? C GLU 117 
488 1 Y 1 C SER 355 ? C SER 265 
489 1 Y 1 C SER 356 ? C SER 266 
490 1 Y 1 C GLU 357 ? C GLU 267 
491 1 Y 1 C SER 358 ? C SER 268 
492 1 Y 1 C GLY 359 ? C GLY 269 
493 1 Y 1 C GLY 360 ? C GLY 270 
494 1 Y 1 C GLY 361 ? C GLY 271 
495 1 Y 1 C SER 362 ? C SER 272 
496 1 Y 1 C SER 363 ? C SER 273 
497 1 Y 1 C GLY 364 ? C GLY 274 
498 1 Y 1 C GLY 365 ? C GLY 275 
499 1 Y 1 C GLY 366 ? C GLY 276 
500 1 Y 1 C SER 367 ? C SER 277 
501 1 Y 1 C THR 368 ? C THR 278 
502 1 Y 1 C TYR 369 ? C TYR 279 
503 1 Y 1 C LYS 370 ? C LYS 280 
504 1 Y 1 C LEU 371 ? C LEU 281 
505 1 Y 1 C ILE 372 ? C ILE 282 
506 1 Y 1 C LEU 373 ? C LEU 283 
507 1 Y 1 C ASN 374 ? C ASN 284 
508 1 Y 1 C GLY 375 ? C GLY 285 
509 1 Y 1 C LYS 376 ? C LYS 286 
510 1 Y 1 C THR 377 ? C THR 287 
511 1 Y 1 C LEU 378 ? C LEU 288 
512 1 Y 1 C LYS 379 ? C LYS 289 
513 1 Y 1 C GLY 380 ? C GLY 290 
514 1 Y 1 C GLU 381 ? C GLU 291 
515 1 Y 1 C THR 382 ? C THR 292 
516 1 Y 1 C THR 383 ? C THR 293 
517 1 Y 1 C THR 384 ? C THR 294 
518 1 Y 1 C GLU 385 ? C GLU 295 
519 1 Y 1 C ALA 386 ? C ALA 296 
520 1 Y 1 C VAL 387 ? C VAL 297 
521 1 Y 1 C ASP 388 ? C ASP 298 
522 1 Y 1 C ALA 389 ? C ALA 299 
523 1 Y 1 C ALA 390 ? C ALA 300 
524 1 Y 1 C THR 391 ? C THR 301 
525 1 Y 1 C ALA 392 ? C ALA 302 
526 1 Y 1 C GLU 393 ? C GLU 303 
527 1 Y 1 C LYS 394 ? C LYS 304 
528 1 Y 1 C VAL 395 ? C VAL 305 
529 1 Y 1 C PHE 396 ? C PHE 306 
530 1 Y 1 C LYS 397 ? C LYS 307 
531 1 Y 1 C GLN 398 ? C GLN 308 
532 1 Y 1 C TYR 399 ? C TYR 309 
533 1 Y 1 C ALA 400 ? C ALA 310 
534 1 Y 1 C ASN 401 ? C ASN 311 
535 1 Y 1 C ASP 402 ? C ASP 312 
536 1 Y 1 C ASN 403 ? C ASN 313 
537 1 Y 1 C GLY 404 ? C GLY 314 
538 1 Y 1 C VAL 405 ? C VAL 315 
539 1 Y 1 C ASP 406 ? C ASP 316 
540 1 Y 1 C GLY 407 ? C GLY 317 
541 1 Y 1 C GLU 408 ? C GLU 318 
542 1 Y 1 C TRP 409 ? C TRP 319 
543 1 Y 1 C THR 410 ? C THR 320 
544 1 Y 1 C TYR 411 ? C TYR 321 
545 1 Y 1 C ASP 412 ? C ASP 322 
546 1 Y 1 C ASP 413 ? C ASP 323 
547 1 Y 1 C ALA 414 ? C ALA 324 
548 1 Y 1 C THR 415 ? C THR 325 
549 1 Y 1 C LYS 416 ? C LYS 326 
550 1 Y 1 C THR 417 ? C THR 327 
551 1 Y 1 C PHE 418 ? C PHE 328 
552 1 Y 1 C THR 419 ? C THR 329 
553 1 Y 1 C VAL 420 ? C VAL 330 
554 1 Y 1 C THR 421 ? C THR 331 
555 1 Y 1 C GLU 422 ? C GLU 332 
556 1 Y 1 D MET 91  ? D MET 1   
557 1 Y 1 D SER 92  ? D SER 2   
558 1 Y 1 D GLU 93  ? D GLU 3   
559 1 Y 1 D GLU 94  ? D GLU 4   
560 1 Y 1 D ASP 95  ? D ASP 5   
561 1 Y 1 D ASN 96  ? D ASN 6   
562 1 Y 1 D ARG 97  ? D ARG 7   
563 1 Y 1 D LEU 98  ? D LEU 8   
564 1 Y 1 D ASN 99  ? D ASN 9   
565 1 Y 1 D GLU 100 ? D GLU 10  
566 1 Y 1 D LEU 101 ? D LEU 11  
567 1 Y 1 D PHE 102 ? D PHE 12  
568 1 Y 1 D ALA 103 ? D ALA 13  
569 1 Y 1 D ASN 104 ? D ASN 14  
570 1 Y 1 D ASP 105 ? D ASP 15  
571 1 Y 1 D LEU 106 ? D LEU 16  
572 1 Y 1 D GLY 107 ? D GLY 17  
573 1 Y 1 D VAL 108 ? D VAL 18  
574 1 Y 1 D GLN 109 ? D GLN 19  
575 1 Y 1 D PRO 110 ? D PRO 20  
576 1 Y 1 D PRO 111 ? D PRO 21  
577 1 Y 1 D CYS 112 ? D CYS 22  
578 1 Y 1 D GLU 113 ? D GLU 23  
579 1 Y 1 D ARG 114 ? D ARG 24  
580 1 Y 1 D SER 115 ? D SER 25  
581 1 Y 1 D LEU 116 ? D LEU 26  
582 1 Y 1 D LYS 117 ? D LYS 27  
583 1 Y 1 D GLU 118 ? D GLU 28  
584 1 Y 1 D GLY 119 ? D GLY 29  
585 1 Y 1 D ARG 120 ? D ARG 30  
586 1 Y 1 D ARG 121 ? D ARG 31  
587 1 Y 1 D PHE 122 ? D PHE 32  
588 1 Y 1 D LEU 123 ? D LEU 33  
589 1 Y 1 D ASN 124 ? D ASN 34  
590 1 Y 1 D ASP 125 ? D ASP 35  
591 1 Y 1 D PHE 126 ? D PHE 36  
592 1 Y 1 D GLU 127 ? D GLU 37  
593 1 Y 1 D ILE 128 ? D ILE 38  
594 1 Y 1 D ALA 129 ? D ALA 39  
595 1 Y 1 D ALA 130 ? D ALA 40  
596 1 Y 1 D LYS 131 ? D LYS 41  
597 1 Y 1 D LYS 132 ? D LYS 42  
598 1 Y 1 D LYS 133 ? D LYS 43  
599 1 Y 1 D LEU 134 ? D LEU 44  
600 1 Y 1 D LEU 135 ? D LEU 45  
601 1 Y 1 D GLU 136 ? D GLU 46  
602 1 Y 1 D LEU 137 ? D LEU 47  
603 1 Y 1 D GLU 138 ? D GLU 48  
604 1 Y 1 D ARG 139 ? D ARG 49  
605 1 Y 1 D LYS 140 ? D LYS 50  
606 1 Y 1 D ALA 141 ? D ALA 51  
607 1 Y 1 D LEU 142 ? D LEU 52  
608 1 Y 1 D GLU 143 ? D GLU 53  
609 1 Y 1 D ASP 144 ? D ASP 54  
610 1 Y 1 D LYS 145 ? D LYS 55  
611 1 Y 1 D GLU 146 ? D GLU 56  
612 1 Y 1 D LYS 147 ? D LYS 57  
613 1 Y 1 D ASN 148 ? D ASN 58  
614 1 Y 1 D LEU 149 ? D LEU 59  
615 1 Y 1 D ASN 150 ? D ASN 60  
616 1 Y 1 D PHE 151 ? D PHE 61  
617 1 Y 1 D VAL 152 ? D VAL 62  
618 1 Y 1 D VAL 153 ? D VAL 63  
619 1 Y 1 D GLU 154 ? D GLU 64  
620 1 Y 1 D SER 155 ? D SER 65  
621 1 Y 1 D GLU 156 ? D GLU 66  
622 1 Y 1 D ARG 157 ? D ARG 67  
623 1 Y 1 D THR 158 ? D THR 68  
624 1 Y 1 D LEU 159 ? D LEU 69  
625 1 Y 1 D PHE 160 ? D PHE 70  
626 1 Y 1 D ASN 161 ? D ASN 71  
627 1 Y 1 D SER 162 ? D SER 72  
628 1 Y 1 D LYS 163 ? D LYS 73  
629 1 Y 1 D LYS 164 ? D LYS 74  
630 1 Y 1 D ARG 165 ? D ARG 75  
631 1 Y 1 D ALA 166 ? D ALA 76  
632 1 Y 1 D PHE 167 ? D PHE 77  
633 1 Y 1 D ASP 168 ? D ASP 78  
634 1 Y 1 D ASN 169 ? D ASN 79  
635 1 Y 1 D ASP 170 ? D ASP 80  
636 1 Y 1 D GLU 171 ? D GLU 81  
637 1 Y 1 D CYS 172 ? D CYS 82  
638 1 Y 1 D TYR 173 ? D TYR 83  
639 1 Y 1 D ASN 174 ? D ASN 84  
640 1 Y 1 D ASP 175 ? D ASP 85  
641 1 Y 1 D ARG 176 ? D ARG 86  
642 1 Y 1 D CYS 177 ? D CYS 87  
643 1 Y 1 D LYS 178 ? D LYS 88  
644 1 Y 1 D LEU 179 ? D LEU 89  
645 1 Y 1 D PHE 180 ? D PHE 90  
646 1 Y 1 D ARG 181 ? D ARG 91  
647 1 Y 1 D GLY 182 ? D GLY 92  
648 1 Y 1 D ILE 183 ? D ILE 93  
649 1 Y 1 D VAL 184 ? D VAL 94  
650 1 Y 1 D ASN 185 ? D ASN 95  
651 1 Y 1 D GLU 186 ? D GLU 96  
652 1 Y 1 D TRP 187 ? D TRP 97  
653 1 Y 1 D GLY 188 ? D GLY 98  
654 1 Y 1 D ARG 189 ? D ARG 99  
655 1 Y 1 D SER 190 ? D SER 100 
656 1 Y 1 D GLU 191 ? D GLU 101 
657 1 Y 1 D ARG 192 ? D ARG 102 
658 1 Y 1 D THR 193 ? D THR 103 
659 1 Y 1 D LEU 194 ? D LEU 104 
660 1 Y 1 D ASP 195 ? D ASP 105 
661 1 Y 1 D SER 196 ? D SER 106 
662 1 Y 1 D LEU 197 ? D LEU 107 
663 1 Y 1 D ASP 198 ? D ASP 108 
664 1 Y 1 D GLU 199 ? D GLU 109 
665 1 Y 1 D PRO 200 ? D PRO 110 
666 1 Y 1 D PRO 201 ? D PRO 111 
667 1 Y 1 D ALA 202 ? D ALA 112 
668 1 Y 1 D TRP 203 ? D TRP 113 
669 1 Y 1 D PHE 204 ? D PHE 114 
670 1 Y 1 D ARG 205 ? D ARG 115 
671 1 Y 1 D ARG 206 ? D ARG 116 
672 1 Y 1 D GLU 207 ? D GLU 117 
673 1 Y 1 D SER 355 ? D SER 265 
674 1 Y 1 D SER 356 ? D SER 266 
675 1 Y 1 D GLU 357 ? D GLU 267 
676 1 Y 1 D SER 358 ? D SER 268 
677 1 Y 1 D GLY 359 ? D GLY 269 
678 1 Y 1 D GLY 360 ? D GLY 270 
679 1 Y 1 D GLY 361 ? D GLY 271 
680 1 Y 1 D SER 362 ? D SER 272 
681 1 Y 1 D SER 363 ? D SER 273 
682 1 Y 1 D GLY 364 ? D GLY 274 
683 1 Y 1 D GLY 365 ? D GLY 275 
684 1 Y 1 D GLY 366 ? D GLY 276 
685 1 Y 1 D SER 367 ? D SER 277 
686 1 Y 1 D THR 368 ? D THR 278 
687 1 Y 1 D TYR 369 ? D TYR 279 
688 1 Y 1 D LYS 370 ? D LYS 280 
689 1 Y 1 D LEU 371 ? D LEU 281 
690 1 Y 1 D ILE 372 ? D ILE 282 
691 1 Y 1 D LEU 373 ? D LEU 283 
692 1 Y 1 D ASN 374 ? D ASN 284 
693 1 Y 1 D GLY 375 ? D GLY 285 
694 1 Y 1 D LYS 376 ? D LYS 286 
695 1 Y 1 D THR 377 ? D THR 287 
696 1 Y 1 D LEU 378 ? D LEU 288 
697 1 Y 1 D LYS 379 ? D LYS 289 
698 1 Y 1 D GLY 380 ? D GLY 290 
699 1 Y 1 D GLU 381 ? D GLU 291 
700 1 Y 1 D THR 382 ? D THR 292 
701 1 Y 1 D THR 383 ? D THR 293 
702 1 Y 1 D THR 384 ? D THR 294 
703 1 Y 1 D GLU 385 ? D GLU 295 
704 1 Y 1 D ALA 386 ? D ALA 296 
705 1 Y 1 D VAL 387 ? D VAL 297 
706 1 Y 1 D ASP 388 ? D ASP 298 
707 1 Y 1 D ALA 389 ? D ALA 299 
708 1 Y 1 D ALA 390 ? D ALA 300 
709 1 Y 1 D THR 391 ? D THR 301 
710 1 Y 1 D ALA 392 ? D ALA 302 
711 1 Y 1 D GLU 393 ? D GLU 303 
712 1 Y 1 D LYS 394 ? D LYS 304 
713 1 Y 1 D VAL 395 ? D VAL 305 
714 1 Y 1 D PHE 396 ? D PHE 306 
715 1 Y 1 D LYS 397 ? D LYS 307 
716 1 Y 1 D GLN 398 ? D GLN 308 
717 1 Y 1 D TYR 399 ? D TYR 309 
718 1 Y 1 D ALA 400 ? D ALA 310 
719 1 Y 1 D ASN 401 ? D ASN 311 
720 1 Y 1 D ASP 402 ? D ASP 312 
721 1 Y 1 D ASN 403 ? D ASN 313 
722 1 Y 1 D GLY 404 ? D GLY 314 
723 1 Y 1 D VAL 405 ? D VAL 315 
724 1 Y 1 D ASP 406 ? D ASP 316 
725 1 Y 1 D GLY 407 ? D GLY 317 
726 1 Y 1 D GLU 408 ? D GLU 318 
727 1 Y 1 D TRP 409 ? D TRP 319 
728 1 Y 1 D THR 410 ? D THR 320 
729 1 Y 1 D TYR 411 ? D TYR 321 
730 1 Y 1 D ASP 412 ? D ASP 322 
731 1 Y 1 D ASP 413 ? D ASP 323 
732 1 Y 1 D ALA 414 ? D ALA 324 
733 1 Y 1 D THR 415 ? D THR 325 
734 1 Y 1 D LYS 416 ? D LYS 326 
735 1 Y 1 D THR 417 ? D THR 327 
736 1 Y 1 D PHE 418 ? D PHE 328 
737 1 Y 1 D THR 419 ? D THR 329 
738 1 Y 1 D VAL 420 ? D VAL 330 
739 1 Y 1 D THR 421 ? D THR 331 
740 1 Y 1 D GLU 422 ? D GLU 332 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
ILE N    N N N 137 
ILE CA   C N S 138 
ILE C    C N N 139 
ILE O    O N N 140 
ILE CB   C N S 141 
ILE CG1  C N N 142 
ILE CG2  C N N 143 
ILE CD1  C N N 144 
ILE OXT  O N N 145 
ILE H    H N N 146 
ILE H2   H N N 147 
ILE HA   H N N 148 
ILE HB   H N N 149 
ILE HG12 H N N 150 
ILE HG13 H N N 151 
ILE HG21 H N N 152 
ILE HG22 H N N 153 
ILE HG23 H N N 154 
ILE HD11 H N N 155 
ILE HD12 H N N 156 
ILE HD13 H N N 157 
ILE HXT  H N N 158 
LEU N    N N N 159 
LEU CA   C N S 160 
LEU C    C N N 161 
LEU O    O N N 162 
LEU CB   C N N 163 
LEU CG   C N N 164 
LEU CD1  C N N 165 
LEU CD2  C N N 166 
LEU OXT  O N N 167 
LEU H    H N N 168 
LEU H2   H N N 169 
LEU HA   H N N 170 
LEU HB2  H N N 171 
LEU HB3  H N N 172 
LEU HG   H N N 173 
LEU HD11 H N N 174 
LEU HD12 H N N 175 
LEU HD13 H N N 176 
LEU HD21 H N N 177 
LEU HD22 H N N 178 
LEU HD23 H N N 179 
LEU HXT  H N N 180 
LYS N    N N N 181 
LYS CA   C N S 182 
LYS C    C N N 183 
LYS O    O N N 184 
LYS CB   C N N 185 
LYS CG   C N N 186 
LYS CD   C N N 187 
LYS CE   C N N 188 
LYS NZ   N N N 189 
LYS OXT  O N N 190 
LYS H    H N N 191 
LYS H2   H N N 192 
LYS HA   H N N 193 
LYS HB2  H N N 194 
LYS HB3  H N N 195 
LYS HG2  H N N 196 
LYS HG3  H N N 197 
LYS HD2  H N N 198 
LYS HD3  H N N 199 
LYS HE2  H N N 200 
LYS HE3  H N N 201 
LYS HZ1  H N N 202 
LYS HZ2  H N N 203 
LYS HZ3  H N N 204 
LYS HXT  H N N 205 
MET N    N N N 206 
MET CA   C N S 207 
MET C    C N N 208 
MET O    O N N 209 
MET CB   C N N 210 
MET CG   C N N 211 
MET SD   S N N 212 
MET CE   C N N 213 
MET OXT  O N N 214 
MET H    H N N 215 
MET H2   H N N 216 
MET HA   H N N 217 
MET HB2  H N N 218 
MET HB3  H N N 219 
MET HG2  H N N 220 
MET HG3  H N N 221 
MET HE1  H N N 222 
MET HE2  H N N 223 
MET HE3  H N N 224 
MET HXT  H N N 225 
PHE N    N N N 226 
PHE CA   C N S 227 
PHE C    C N N 228 
PHE O    O N N 229 
PHE CB   C N N 230 
PHE CG   C Y N 231 
PHE CD1  C Y N 232 
PHE CD2  C Y N 233 
PHE CE1  C Y N 234 
PHE CE2  C Y N 235 
PHE CZ   C Y N 236 
PHE OXT  O N N 237 
PHE H    H N N 238 
PHE H2   H N N 239 
PHE HA   H N N 240 
PHE HB2  H N N 241 
PHE HB3  H N N 242 
PHE HD1  H N N 243 
PHE HD2  H N N 244 
PHE HE1  H N N 245 
PHE HE2  H N N 246 
PHE HZ   H N N 247 
PHE HXT  H N N 248 
PRO N    N N N 249 
PRO CA   C N S 250 
PRO C    C N N 251 
PRO O    O N N 252 
PRO CB   C N N 253 
PRO CG   C N N 254 
PRO CD   C N N 255 
PRO OXT  O N N 256 
PRO H    H N N 257 
PRO HA   H N N 258 
PRO HB2  H N N 259 
PRO HB3  H N N 260 
PRO HG2  H N N 261 
PRO HG3  H N N 262 
PRO HD2  H N N 263 
PRO HD3  H N N 264 
PRO HXT  H N N 265 
SER N    N N N 266 
SER CA   C N S 267 
SER C    C N N 268 
SER O    O N N 269 
SER CB   C N N 270 
SER OG   O N N 271 
SER OXT  O N N 272 
SER H    H N N 273 
SER H2   H N N 274 
SER HA   H N N 275 
SER HB2  H N N 276 
SER HB3  H N N 277 
SER HG   H N N 278 
SER HXT  H N N 279 
THR N    N N N 280 
THR CA   C N S 281 
THR C    C N N 282 
THR O    O N N 283 
THR CB   C N R 284 
THR OG1  O N N 285 
THR CG2  C N N 286 
THR OXT  O N N 287 
THR H    H N N 288 
THR H2   H N N 289 
THR HA   H N N 290 
THR HB   H N N 291 
THR HG1  H N N 292 
THR HG21 H N N 293 
THR HG22 H N N 294 
THR HG23 H N N 295 
THR HXT  H N N 296 
TRP N    N N N 297 
TRP CA   C N S 298 
TRP C    C N N 299 
TRP O    O N N 300 
TRP CB   C N N 301 
TRP CG   C Y N 302 
TRP CD1  C Y N 303 
TRP CD2  C Y N 304 
TRP NE1  N Y N 305 
TRP CE2  C Y N 306 
TRP CE3  C Y N 307 
TRP CZ2  C Y N 308 
TRP CZ3  C Y N 309 
TRP CH2  C Y N 310 
TRP OXT  O N N 311 
TRP H    H N N 312 
TRP H2   H N N 313 
TRP HA   H N N 314 
TRP HB2  H N N 315 
TRP HB3  H N N 316 
TRP HD1  H N N 317 
TRP HE1  H N N 318 
TRP HE3  H N N 319 
TRP HZ2  H N N 320 
TRP HZ3  H N N 321 
TRP HH2  H N N 322 
TRP HXT  H N N 323 
TYR N    N N N 324 
TYR CA   C N S 325 
TYR C    C N N 326 
TYR O    O N N 327 
TYR CB   C N N 328 
TYR CG   C Y N 329 
TYR CD1  C Y N 330 
TYR CD2  C Y N 331 
TYR CE1  C Y N 332 
TYR CE2  C Y N 333 
TYR CZ   C Y N 334 
TYR OH   O N N 335 
TYR OXT  O N N 336 
TYR H    H N N 337 
TYR H2   H N N 338 
TYR HA   H N N 339 
TYR HB2  H N N 340 
TYR HB3  H N N 341 
TYR HD1  H N N 342 
TYR HD2  H N N 343 
TYR HE1  H N N 344 
TYR HE2  H N N 345 
TYR HH   H N N 346 
TYR HXT  H N N 347 
VAL N    N N N 348 
VAL CA   C N S 349 
VAL C    C N N 350 
VAL O    O N N 351 
VAL CB   C N N 352 
VAL CG1  C N N 353 
VAL CG2  C N N 354 
VAL OXT  O N N 355 
VAL H    H N N 356 
VAL H2   H N N 357 
VAL HA   H N N 358 
VAL HB   H N N 359 
VAL HG11 H N N 360 
VAL HG12 H N N 361 
VAL HG13 H N N 362 
VAL HG21 H N N 363 
VAL HG22 H N N 364 
VAL HG23 H N N 365 
VAL HXT  H N N 366 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
ILE N   CA   sing N N 129 
ILE N   H    sing N N 130 
ILE N   H2   sing N N 131 
ILE CA  C    sing N N 132 
ILE CA  CB   sing N N 133 
ILE CA  HA   sing N N 134 
ILE C   O    doub N N 135 
ILE C   OXT  sing N N 136 
ILE CB  CG1  sing N N 137 
ILE CB  CG2  sing N N 138 
ILE CB  HB   sing N N 139 
ILE CG1 CD1  sing N N 140 
ILE CG1 HG12 sing N N 141 
ILE CG1 HG13 sing N N 142 
ILE CG2 HG21 sing N N 143 
ILE CG2 HG22 sing N N 144 
ILE CG2 HG23 sing N N 145 
ILE CD1 HD11 sing N N 146 
ILE CD1 HD12 sing N N 147 
ILE CD1 HD13 sing N N 148 
ILE OXT HXT  sing N N 149 
LEU N   CA   sing N N 150 
LEU N   H    sing N N 151 
LEU N   H2   sing N N 152 
LEU CA  C    sing N N 153 
LEU CA  CB   sing N N 154 
LEU CA  HA   sing N N 155 
LEU C   O    doub N N 156 
LEU C   OXT  sing N N 157 
LEU CB  CG   sing N N 158 
LEU CB  HB2  sing N N 159 
LEU CB  HB3  sing N N 160 
LEU CG  CD1  sing N N 161 
LEU CG  CD2  sing N N 162 
LEU CG  HG   sing N N 163 
LEU CD1 HD11 sing N N 164 
LEU CD1 HD12 sing N N 165 
LEU CD1 HD13 sing N N 166 
LEU CD2 HD21 sing N N 167 
LEU CD2 HD22 sing N N 168 
LEU CD2 HD23 sing N N 169 
LEU OXT HXT  sing N N 170 
LYS N   CA   sing N N 171 
LYS N   H    sing N N 172 
LYS N   H2   sing N N 173 
LYS CA  C    sing N N 174 
LYS CA  CB   sing N N 175 
LYS CA  HA   sing N N 176 
LYS C   O    doub N N 177 
LYS C   OXT  sing N N 178 
LYS CB  CG   sing N N 179 
LYS CB  HB2  sing N N 180 
LYS CB  HB3  sing N N 181 
LYS CG  CD   sing N N 182 
LYS CG  HG2  sing N N 183 
LYS CG  HG3  sing N N 184 
LYS CD  CE   sing N N 185 
LYS CD  HD2  sing N N 186 
LYS CD  HD3  sing N N 187 
LYS CE  NZ   sing N N 188 
LYS CE  HE2  sing N N 189 
LYS CE  HE3  sing N N 190 
LYS NZ  HZ1  sing N N 191 
LYS NZ  HZ2  sing N N 192 
LYS NZ  HZ3  sing N N 193 
LYS OXT HXT  sing N N 194 
MET N   CA   sing N N 195 
MET N   H    sing N N 196 
MET N   H2   sing N N 197 
MET CA  C    sing N N 198 
MET CA  CB   sing N N 199 
MET CA  HA   sing N N 200 
MET C   O    doub N N 201 
MET C   OXT  sing N N 202 
MET CB  CG   sing N N 203 
MET CB  HB2  sing N N 204 
MET CB  HB3  sing N N 205 
MET CG  SD   sing N N 206 
MET CG  HG2  sing N N 207 
MET CG  HG3  sing N N 208 
MET SD  CE   sing N N 209 
MET CE  HE1  sing N N 210 
MET CE  HE2  sing N N 211 
MET CE  HE3  sing N N 212 
MET OXT HXT  sing N N 213 
PHE N   CA   sing N N 214 
PHE N   H    sing N N 215 
PHE N   H2   sing N N 216 
PHE CA  C    sing N N 217 
PHE CA  CB   sing N N 218 
PHE CA  HA   sing N N 219 
PHE C   O    doub N N 220 
PHE C   OXT  sing N N 221 
PHE CB  CG   sing N N 222 
PHE CB  HB2  sing N N 223 
PHE CB  HB3  sing N N 224 
PHE CG  CD1  doub Y N 225 
PHE CG  CD2  sing Y N 226 
PHE CD1 CE1  sing Y N 227 
PHE CD1 HD1  sing N N 228 
PHE CD2 CE2  doub Y N 229 
PHE CD2 HD2  sing N N 230 
PHE CE1 CZ   doub Y N 231 
PHE CE1 HE1  sing N N 232 
PHE CE2 CZ   sing Y N 233 
PHE CE2 HE2  sing N N 234 
PHE CZ  HZ   sing N N 235 
PHE OXT HXT  sing N N 236 
PRO N   CA   sing N N 237 
PRO N   CD   sing N N 238 
PRO N   H    sing N N 239 
PRO CA  C    sing N N 240 
PRO CA  CB   sing N N 241 
PRO CA  HA   sing N N 242 
PRO C   O    doub N N 243 
PRO C   OXT  sing N N 244 
PRO CB  CG   sing N N 245 
PRO CB  HB2  sing N N 246 
PRO CB  HB3  sing N N 247 
PRO CG  CD   sing N N 248 
PRO CG  HG2  sing N N 249 
PRO CG  HG3  sing N N 250 
PRO CD  HD2  sing N N 251 
PRO CD  HD3  sing N N 252 
PRO OXT HXT  sing N N 253 
SER N   CA   sing N N 254 
SER N   H    sing N N 255 
SER N   H2   sing N N 256 
SER CA  C    sing N N 257 
SER CA  CB   sing N N 258 
SER CA  HA   sing N N 259 
SER C   O    doub N N 260 
SER C   OXT  sing N N 261 
SER CB  OG   sing N N 262 
SER CB  HB2  sing N N 263 
SER CB  HB3  sing N N 264 
SER OG  HG   sing N N 265 
SER OXT HXT  sing N N 266 
THR N   CA   sing N N 267 
THR N   H    sing N N 268 
THR N   H2   sing N N 269 
THR CA  C    sing N N 270 
THR CA  CB   sing N N 271 
THR CA  HA   sing N N 272 
THR C   O    doub N N 273 
THR C   OXT  sing N N 274 
THR CB  OG1  sing N N 275 
THR CB  CG2  sing N N 276 
THR CB  HB   sing N N 277 
THR OG1 HG1  sing N N 278 
THR CG2 HG21 sing N N 279 
THR CG2 HG22 sing N N 280 
THR CG2 HG23 sing N N 281 
THR OXT HXT  sing N N 282 
TRP N   CA   sing N N 283 
TRP N   H    sing N N 284 
TRP N   H2   sing N N 285 
TRP CA  C    sing N N 286 
TRP CA  CB   sing N N 287 
TRP CA  HA   sing N N 288 
TRP C   O    doub N N 289 
TRP C   OXT  sing N N 290 
TRP CB  CG   sing N N 291 
TRP CB  HB2  sing N N 292 
TRP CB  HB3  sing N N 293 
TRP CG  CD1  doub Y N 294 
TRP CG  CD2  sing Y N 295 
TRP CD1 NE1  sing Y N 296 
TRP CD1 HD1  sing N N 297 
TRP CD2 CE2  doub Y N 298 
TRP CD2 CE3  sing Y N 299 
TRP NE1 CE2  sing Y N 300 
TRP NE1 HE1  sing N N 301 
TRP CE2 CZ2  sing Y N 302 
TRP CE3 CZ3  doub Y N 303 
TRP CE3 HE3  sing N N 304 
TRP CZ2 CH2  doub Y N 305 
TRP CZ2 HZ2  sing N N 306 
TRP CZ3 CH2  sing Y N 307 
TRP CZ3 HZ3  sing N N 308 
TRP CH2 HH2  sing N N 309 
TRP OXT HXT  sing N N 310 
TYR N   CA   sing N N 311 
TYR N   H    sing N N 312 
TYR N   H2   sing N N 313 
TYR CA  C    sing N N 314 
TYR CA  CB   sing N N 315 
TYR CA  HA   sing N N 316 
TYR C   O    doub N N 317 
TYR C   OXT  sing N N 318 
TYR CB  CG   sing N N 319 
TYR CB  HB2  sing N N 320 
TYR CB  HB3  sing N N 321 
TYR CG  CD1  doub Y N 322 
TYR CG  CD2  sing Y N 323 
TYR CD1 CE1  sing Y N 324 
TYR CD1 HD1  sing N N 325 
TYR CD2 CE2  doub Y N 326 
TYR CD2 HD2  sing N N 327 
TYR CE1 CZ   doub Y N 328 
TYR CE1 HE1  sing N N 329 
TYR CE2 CZ   sing Y N 330 
TYR CE2 HE2  sing N N 331 
TYR CZ  OH   sing N N 332 
TYR OH  HH   sing N N 333 
TYR OXT HXT  sing N N 334 
VAL N   CA   sing N N 335 
VAL N   H    sing N N 336 
VAL N   H2   sing N N 337 
VAL CA  C    sing N N 338 
VAL CA  CB   sing N N 339 
VAL CA  HA   sing N N 340 
VAL C   O    doub N N 341 
VAL C   OXT  sing N N 342 
VAL CB  CG1  sing N N 343 
VAL CB  CG2  sing N N 344 
VAL CB  HB   sing N N 345 
VAL CG1 HG11 sing N N 346 
VAL CG1 HG12 sing N N 347 
VAL CG1 HG13 sing N N 348 
VAL CG2 HG21 sing N N 349 
VAL CG2 HG22 sing N N 350 
VAL CG2 HG23 sing N N 351 
VAL OXT HXT  sing N N 352 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-24 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JA6 
_em_admin.last_update        2024-11-13 
_em_admin.map_release_date   2024-11-13 
_em_admin.title              'Cryo-EM structure of Tdk1 tetramer complex' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 2   mM KH2PO4  1 'Potassium phosphate monobasic' 
1 4   mM Na2HPO4 2 'Sodium Phosphate Dibasic'      
1 136 mM NaCl    3 'Sodium chloride'               
1 2.6 mM KCl     4 'Potassium chloride'            
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.15 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 1 284812 'Schizosaccharomyces pombe 972h-' ? ? ? ? ? 
? ? 1 2 1320   'Streptococcus sp. group G'       ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   1 
_em_entity_assembly_recombinant.ncbi_tax_id          284812 
_em_entity_assembly_recombinant.organism             'Schizosaccharomyces pombe 972h-' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       SUPER-RESOLUTION 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     787 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Tridiem 4K' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'CRYSTALLOGRAPHY MERGING'       ? 1  1 1 1 ?         ?    
'IMAGE ACQUISITION'             ? 2  ? ? 1 SerialEM  ?    
MASKING                         ? 3  ? ? ? ?         ?    
'CTF CORRECTION'                ? 4  1 ? ? Gctf      1.06 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?    
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?    
'MODEL FITTING'                 ? 7  ? 1 ? Coot      ?    
OTHER                           ? 8  ? ? ? ?         ?    
'MODEL REFINEMENT'              ? 9  ? 1 ? PHENIX    ?    
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? cryoSPARC 3.0  
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? cryoSPARC 3.0  
CLASSIFICATION                  ? 12 1 ? ? cryoSPARC 3.0  
RECONSTRUCTION                  ? 13 1 ? ? cryoSPARC 3.0  
'PARTICLE SELECTION'            ? 14 1 1 1 ?         ?    
'VOLUME SELECTION'              ? 15 1 1 1 ?         ?    
'SERIES ALIGNMENT'              ? 16 1 1 1 ?         ?    
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ?         ?    
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ?         ?    
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ?         ?    
# 
_em_specimen.concentration           0.1 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)'    China '32071199, 91940302' 1 
'Chinese Academy of Sciences'                            China XDB37010201          2 
'National Basic Research Program of China (973 Program)' China 2017YFA0504600       3 
# 
_atom_sites.entry_id                    9JA6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . MET A 1 118 ? 134.417 123.731 70.001  1.00 184.72 ? 208 MET A N   1 
ATOM 2    C CA  . MET A 1 118 ? 133.176 123.234 70.585  1.00 184.72 ? 208 MET A CA  1 
ATOM 3    C C   . MET A 1 118 ? 133.422 121.951 71.370  1.00 184.72 ? 208 MET A C   1 
ATOM 4    O O   . MET A 1 118 ? 132.777 121.701 72.397  1.00 184.72 ? 208 MET A O   1 
ATOM 5    C CB  . MET A 1 118 ? 132.127 122.996 69.498  1.00 50.00  ? 208 MET A CB  1 
ATOM 6    C CG  . MET A 1 118 ? 131.651 124.262 68.804  1.00 50.00  ? 208 MET A CG  1 
ATOM 7    S SD  . MET A 1 118 ? 130.897 125.438 69.942  1.00 50.00  ? 208 MET A SD  1 
ATOM 8    C CE  . MET A 1 118 ? 129.421 124.544 70.423  1.00 50.00  ? 208 MET A CE  1 
ATOM 9    N N   . GLY A 1 119 ? 134.370 121.130 70.907  1.00 183.00 ? 209 GLY A N   1 
ATOM 10   C CA  . GLY A 1 119 ? 134.838 120.019 71.731  1.00 183.00 ? 209 GLY A CA  1 
ATOM 11   C C   . GLY A 1 119 ? 135.234 120.518 73.108  1.00 183.00 ? 209 GLY A C   1 
ATOM 12   O O   . GLY A 1 119 ? 134.631 120.138 74.123  1.00 183.00 ? 209 GLY A O   1 
ATOM 13   N N   . GLU A 1 120 ? 136.228 121.407 73.150  1.00 179.63 ? 210 GLU A N   1 
ATOM 14   C CA  . GLU A 1 120 ? 136.701 121.956 74.412  1.00 179.63 ? 210 GLU A CA  1 
ATOM 15   C C   . GLU A 1 120 ? 135.555 122.508 75.240  1.00 179.63 ? 210 GLU A C   1 
ATOM 16   O O   . GLU A 1 120 ? 135.539 122.343 76.462  1.00 179.63 ? 210 GLU A O   1 
ATOM 17   C CB  . GLU A 1 120 ? 137.742 123.049 74.161  1.00 50.00  ? 210 GLU A CB  1 
ATOM 18   C CG  . GLU A 1 120 ? 139.042 122.542 73.556  1.00 50.00  ? 210 GLU A CG  1 
ATOM 19   C CD  . GLU A 1 120 ? 140.019 123.664 73.256  1.00 50.00  ? 210 GLU A CD  1 
ATOM 20   O OE1 . GLU A 1 120 ? 139.617 124.843 73.340  1.00 50.00  ? 210 GLU A OE1 1 
ATOM 21   O OE2 . GLU A 1 120 ? 141.188 123.365 72.934  1.00 50.00  ? 210 GLU A OE2 1 
ATOM 22   N N   . TRP A 1 121 ? 134.596 123.169 74.592  1.00 174.02 ? 211 TRP A N   1 
ATOM 23   C CA  . TRP A 1 121 ? 133.390 123.596 75.286  1.00 174.02 ? 211 TRP A CA  1 
ATOM 24   C C   . TRP A 1 121 ? 132.737 122.423 76.001  1.00 174.02 ? 211 TRP A C   1 
ATOM 25   O O   . TRP A 1 121 ? 132.372 122.525 77.176  1.00 174.02 ? 211 TRP A O   1 
ATOM 26   C CB  . TRP A 1 121 ? 132.402 124.233 74.307  1.00 50.00  ? 211 TRP A CB  1 
ATOM 27   C CG  . TRP A 1 121 ? 132.858 125.556 73.771  1.00 50.00  ? 211 TRP A CG  1 
ATOM 28   C CD1 . TRP A 1 121 ? 133.522 125.785 72.601  1.00 50.00  ? 211 TRP A CD1 1 
ATOM 29   C CD2 . TRP A 1 121 ? 132.683 126.838 74.388  1.00 50.00  ? 211 TRP A CD2 1 
ATOM 30   N NE1 . TRP A 1 121 ? 133.773 127.127 72.452  1.00 50.00  ? 211 TRP A NE1 1 
ATOM 31   C CE2 . TRP A 1 121 ? 133.267 127.797 73.534  1.00 50.00  ? 211 TRP A CE2 1 
ATOM 32   C CE3 . TRP A 1 121 ? 132.093 127.276 75.578  1.00 50.00  ? 211 TRP A CE3 1 
ATOM 33   C CZ2 . TRP A 1 121 ? 133.277 129.158 73.833  1.00 50.00  ? 211 TRP A CZ2 1 
ATOM 34   C CZ3 . TRP A 1 121 ? 132.104 128.627 75.871  1.00 50.00  ? 211 TRP A CZ3 1 
ATOM 35   C CH2 . TRP A 1 121 ? 132.691 129.552 75.003  1.00 50.00  ? 211 TRP A CH2 1 
ATOM 36   N N   . LYS A 1 122 ? 132.595 121.298 75.306  1.00 170.89 ? 212 LYS A N   1 
ATOM 37   C CA  . LYS A 1 122 ? 131.949 120.138 75.904  1.00 170.89 ? 212 LYS A CA  1 
ATOM 38   C C   . LYS A 1 122 ? 132.737 119.567 77.072  1.00 170.89 ? 212 LYS A C   1 
ATOM 39   O O   . LYS A 1 122 ? 132.156 119.316 78.137  1.00 170.89 ? 212 LYS A O   1 
ATOM 40   C CB  . LYS A 1 122 ? 131.735 119.053 74.847  1.00 50.00  ? 212 LYS A CB  1 
ATOM 41   C CG  . LYS A 1 122 ? 130.743 119.433 73.759  1.00 50.00  ? 212 LYS A CG  1 
ATOM 42   C CD  . LYS A 1 122 ? 130.597 118.323 72.732  1.00 50.00  ? 212 LYS A CD  1 
ATOM 43   C CE  . LYS A 1 122 ? 129.588 118.692 71.657  1.00 50.00  ? 212 LYS A CE  1 
ATOM 44   N NZ  . LYS A 1 122 ? 129.453 117.623 70.631  1.00 50.00  ? 212 LYS A NZ  1 
ATOM 45   N N   . LYS A 1 123 ? 134.040 119.350 76.898  1.00 160.10 ? 213 LYS A N   1 
ATOM 46   C CA  . LYS A 1 123 ? 134.807 118.821 78.021  1.00 160.10 ? 213 LYS A CA  1 
ATOM 47   C C   . LYS A 1 123 ? 134.813 119.803 79.183  1.00 160.10 ? 213 LYS A C   1 
ATOM 48   O O   . LYS A 1 123 ? 134.834 119.395 80.351  1.00 160.10 ? 213 LYS A O   1 
ATOM 49   C CB  . LYS A 1 123 ? 136.240 118.504 77.591  1.00 50.00  ? 213 LYS A CB  1 
ATOM 50   C CG  . LYS A 1 123 ? 136.352 117.355 76.601  1.00 50.00  ? 213 LYS A CG  1 
ATOM 51   C CD  . LYS A 1 123 ? 137.797 117.110 76.199  1.00 50.00  ? 213 LYS A CD  1 
ATOM 52   C CE  . LYS A 1 123 ? 137.912 115.947 75.228  1.00 50.00  ? 213 LYS A CE  1 
ATOM 53   N NZ  . LYS A 1 123 ? 139.320 115.712 74.807  1.00 50.00  ? 213 LYS A NZ  1 
ATOM 54   N N   . ALA A 1 124 ? 134.884 121.078 78.837  1.00 162.44 ? 214 ALA A N   1 
ATOM 55   C CA  . ALA A 1 124 ? 134.899 122.085 79.853  1.00 162.44 ? 214 ALA A CA  1 
ATOM 56   C C   . ALA A 1 124 ? 133.617 121.963 80.587  1.00 162.44 ? 214 ALA A C   1 
ATOM 57   O O   . ALA A 1 124 ? 133.558 122.065 81.830  1.00 162.44 ? 214 ALA A O   1 
ATOM 58   C CB  . ALA A 1 124 ? 135.080 123.475 79.263  1.00 50.00  ? 214 ALA A CB  1 
ATOM 59   N N   . ARG A 1 125 ? 132.543 121.792 79.829  1.00 152.39 ? 215 ARG A N   1 
ATOM 60   C CA  . ARG A 1 125 ? 131.228 121.687 80.431  1.00 152.39 ? 215 ARG A CA  1 
ATOM 61   C C   . ARG A 1 125 ? 131.198 120.559 81.444  1.00 152.39 ? 215 ARG A C   1 
ATOM 62   O O   . ARG A 1 125 ? 130.662 120.713 82.541  1.00 152.39 ? 215 ARG A O   1 
ATOM 63   C CB  . ARG A 1 125 ? 130.183 121.465 79.341  1.00 50.00  ? 215 ARG A CB  1 
ATOM 64   C CG  . ARG A 1 125 ? 128.859 120.899 79.817  1.00 50.00  ? 215 ARG A CG  1 
ATOM 65   C CD  . ARG A 1 125 ? 127.823 121.025 78.714  1.00 50.00  ? 215 ARG A CD  1 
ATOM 66   N NE  . ARG A 1 125 ? 126.701 120.113 78.897  1.00 50.00  ? 215 ARG A NE  1 
ATOM 67   C CZ  . ARG A 1 125 ? 126.640 118.897 78.364  1.00 50.00  ? 215 ARG A CZ  1 
ATOM 68   N NH1 . ARG A 1 125 ? 127.639 118.450 77.617  1.00 50.00  ? 215 ARG A NH1 1 
ATOM 69   N NH2 . ARG A 1 125 ? 125.580 118.130 78.575  1.00 50.00  ? 215 ARG A NH2 1 
ATOM 70   N N   . GLU A 1 126 ? 131.781 119.424 81.084  1.00 142.70 ? 216 GLU A N   1 
ATOM 71   C CA  . GLU A 1 126 ? 131.735 118.290 81.987  1.00 142.70 ? 216 GLU A CA  1 
ATOM 72   C C   . GLU A 1 126 ? 132.509 118.563 83.260  1.00 142.70 ? 216 GLU A C   1 
ATOM 73   O O   . GLU A 1 126 ? 132.006 118.322 84.355  1.00 142.70 ? 216 GLU A O   1 
ATOM 74   C CB  . GLU A 1 126 ? 132.283 117.038 81.298  1.00 50.00  ? 216 GLU A CB  1 
ATOM 75   C CG  . GLU A 1 126 ? 131.423 116.535 80.149  1.00 50.00  ? 216 GLU A CG  1 
ATOM 76   C CD  . GLU A 1 126 ? 132.036 115.338 79.446  1.00 50.00  ? 216 GLU A CD  1 
ATOM 77   O OE1 . GLU A 1 126 ? 133.209 115.018 79.727  1.00 50.00  ? 216 GLU A OE1 1 
ATOM 78   O OE2 . GLU A 1 126 ? 131.343 114.718 78.612  1.00 50.00  ? 216 GLU A OE2 1 
ATOM 79   N N   . GLU A 1 127 ? 133.675 119.179 83.129  1.00 144.58 ? 217 GLU A N   1 
ATOM 80   C CA  . GLU A 1 127 ? 134.507 119.394 84.289  1.00 144.58 ? 217 GLU A CA  1 
ATOM 81   C C   . GLU A 1 127 ? 133.727 120.263 85.198  1.00 144.58 ? 217 GLU A C   1 
ATOM 82   O O   . GLU A 1 127 ? 133.698 120.062 86.404  1.00 144.58 ? 217 GLU A O   1 
ATOM 83   C CB  . GLU A 1 127 ? 135.847 120.033 83.917  1.00 50.00  ? 217 GLU A CB  1 
ATOM 84   C CG  . GLU A 1 127 ? 136.778 119.115 83.140  1.00 50.00  ? 217 GLU A CG  1 
ATOM 85   C CD  . GLU A 1 127 ? 138.064 119.806 82.728  1.00 50.00  ? 217 GLU A CD  1 
ATOM 86   O OE1 . GLU A 1 127 ? 138.150 121.043 82.878  1.00 50.00  ? 217 GLU A OE1 1 
ATOM 87   O OE2 . GLU A 1 127 ? 138.987 119.113 82.251  1.00 50.00  ? 217 GLU A OE2 1 
ATOM 88   N N   . ASP A 1 128 ? 133.058 121.257 84.628  1.00 142.45 ? 218 ASP A N   1 
ATOM 89   C CA  . ASP A 1 128 ? 132.226 122.138 85.430  1.00 142.45 ? 218 ASP A CA  1 
ATOM 90   C C   . ASP A 1 128 ? 131.225 121.322 86.223  1.00 142.45 ? 218 ASP A C   1 
ATOM 91   O O   . ASP A 1 128 ? 131.067 121.520 87.422  1.00 142.45 ? 218 ASP A O   1 
ATOM 92   C CB  . ASP A 1 128 ? 131.495 123.138 84.540  1.00 50.00  ? 218 ASP A CB  1 
ATOM 93   C CG  . ASP A 1 128 ? 132.444 124.003 83.742  1.00 50.00  ? 218 ASP A CG  1 
ATOM 94   O OD1 . ASP A 1 128 ? 133.645 124.041 84.082  1.00 50.00  ? 218 ASP A OD1 1 
ATOM 95   O OD2 . ASP A 1 128 ? 131.991 124.645 82.771  1.00 50.00  ? 218 ASP A OD2 1 
ATOM 96   N N   . LYS A 1 129 ? 130.547 120.401 85.552  1.00 134.55 ? 219 LYS A N   1 
ATOM 97   C CA  . LYS A 1 129 ? 129.564 119.567 86.228  1.00 134.55 ? 219 LYS A CA  1 
ATOM 98   C C   . LYS A 1 129 ? 130.210 118.822 87.382  1.00 134.55 ? 219 LYS A C   1 
ATOM 99   O O   . LYS A 1 129 ? 129.669 118.790 88.484  1.00 134.55 ? 219 LYS A O   1 
ATOM 100  C CB  . LYS A 1 129 ? 128.921 118.607 85.234  1.00 50.00  ? 219 LYS A CB  1 
ATOM 101  C CG  . LYS A 1 129 ? 128.268 119.336 84.073  1.00 50.00  ? 219 LYS A CG  1 
ATOM 102  C CD  . LYS A 1 129 ? 127.461 118.399 83.195  1.00 50.00  ? 219 LYS A CD  1 
ATOM 103  C CE  . LYS A 1 129 ? 126.641 119.185 82.187  1.00 50.00  ? 219 LYS A CE  1 
ATOM 104  N NZ  . LYS A 1 129 ? 125.660 118.317 81.482  1.00 50.00  ? 219 LYS A NZ  1 
ATOM 105  N N   . GLU A 1 130 ? 131.362 118.211 87.143  1.00 137.83 ? 220 GLU A N   1 
ATOM 106  C CA  . GLU A 1 130 ? 132.075 117.570 88.242  1.00 137.83 ? 220 GLU A CA  1 
ATOM 107  C C   . GLU A 1 130 ? 132.381 118.580 89.336  1.00 137.83 ? 220 GLU A C   1 
ATOM 108  O O   . GLU A 1 130 ? 132.189 118.301 90.526  1.00 137.83 ? 220 GLU A O   1 
ATOM 109  C CB  . GLU A 1 130 ? 133.354 116.885 87.756  1.00 137.83 ? 220 GLU A CB  1 
ATOM 110  C CG  . GLU A 1 130 ? 133.117 115.535 87.080  1.00 137.83 ? 220 GLU A CG  1 
ATOM 111  C CD  . GLU A 1 130 ? 133.001 115.621 85.578  1.00 137.83 ? 220 GLU A CD  1 
ATOM 112  O OE1 . GLU A 1 130 ? 133.632 116.515 84.996  1.00 137.83 ? 220 GLU A OE1 1 
ATOM 113  O OE2 . GLU A 1 130 ? 132.279 114.796 84.981  1.00 137.83 ? 220 GLU A OE2 1 
ATOM 114  N N   . TRP A 1 131 ? 132.832 119.771 88.947  1.00 123.03 ? 221 TRP A N   1 
ATOM 115  C CA  . TRP A 1 131 ? 133.032 120.839 89.911  1.00 123.03 ? 221 TRP A CA  1 
ATOM 116  C C   . TRP A 1 131 ? 131.765 121.098 90.703  1.00 123.03 ? 221 TRP A C   1 
ATOM 117  O O   . TRP A 1 131 ? 131.816 121.335 91.919  1.00 123.03 ? 221 TRP A O   1 
ATOM 118  C CB  . TRP A 1 131 ? 133.480 122.102 89.188  1.00 123.03 ? 221 TRP A CB  1 
ATOM 119  C CG  . TRP A 1 131 ? 133.526 123.274 90.069  1.00 123.03 ? 221 TRP A CG  1 
ATOM 120  C CD1 . TRP A 1 131 ? 134.378 123.483 91.104  1.00 123.03 ? 221 TRP A CD1 1 
ATOM 121  C CD2 . TRP A 1 131 ? 132.667 124.409 90.017  1.00 123.03 ? 221 TRP A CD2 1 
ATOM 122  N NE1 . TRP A 1 131 ? 134.113 124.687 91.696  1.00 123.03 ? 221 TRP A NE1 1 
ATOM 123  C CE2 . TRP A 1 131 ? 133.062 125.275 91.046  1.00 123.03 ? 221 TRP A CE2 1 
ATOM 124  C CE3 . TRP A 1 131 ? 131.603 124.778 89.198  1.00 123.03 ? 221 TRP A CE3 1 
ATOM 125  C CZ2 . TRP A 1 131 ? 132.429 126.485 91.279  1.00 123.03 ? 221 TRP A CZ2 1 
ATOM 126  C CZ3 . TRP A 1 131 ? 130.981 125.982 89.428  1.00 123.03 ? 221 TRP A CZ3 1 
ATOM 127  C CH2 . TRP A 1 131 ? 131.395 126.822 90.458  1.00 123.03 ? 221 TRP A CH2 1 
ATOM 128  N N   . ARG A 1 132 ? 130.624 121.041 90.026  1.00 120.82 ? 222 ARG A N   1 
ATOM 129  C CA  . ARG A 1 132 ? 129.350 121.187 90.706  1.00 120.82 ? 222 ARG A CA  1 
ATOM 130  C C   . ARG A 1 132 ? 129.198 120.125 91.780  1.00 120.82 ? 222 ARG A C   1 
ATOM 131  O O   . ARG A 1 132 ? 128.692 120.399 92.869  1.00 120.82 ? 222 ARG A O   1 
ATOM 132  C CB  . ARG A 1 132 ? 128.193 121.094 89.714  1.00 120.82 ? 222 ARG A CB  1 
ATOM 133  C CG  . ARG A 1 132 ? 128.260 122.032 88.540  1.00 120.82 ? 222 ARG A CG  1 
ATOM 134  C CD  . ARG A 1 132 ? 126.913 122.056 87.848  1.00 120.82 ? 222 ARG A CD  1 
ATOM 135  N NE  . ARG A 1 132 ? 127.021 122.149 86.400  1.00 120.82 ? 222 ARG A NE  1 
ATOM 136  C CZ  . ARG A 1 132 ? 127.066 123.294 85.737  1.00 120.82 ? 222 ARG A CZ  1 
ATOM 137  N NH1 . ARG A 1 132 ? 127.031 124.439 86.399  1.00 120.82 ? 222 ARG A NH1 1 
ATOM 138  N NH2 . ARG A 1 132 ? 127.159 123.295 84.417  1.00 120.82 ? 222 ARG A NH2 1 
ATOM 139  N N   . LYS A 1 133 ? 129.619 118.898 91.484  1.00 117.93 ? 223 LYS A N   1 
ATOM 140  C CA  . LYS A 1 133 ? 129.428 117.818 92.442  1.00 117.93 ? 223 LYS A CA  1 
ATOM 141  C C   . LYS A 1 133 ? 130.243 118.057 93.703  1.00 117.93 ? 223 LYS A C   1 
ATOM 142  O O   . LYS A 1 133 ? 129.747 117.877 94.822  1.00 117.93 ? 223 LYS A O   1 
ATOM 143  C CB  . LYS A 1 133 ? 129.784 116.478 91.796  1.00 117.93 ? 223 LYS A CB  1 
ATOM 144  C CG  . LYS A 1 133 ? 128.564 115.725 91.274  1.00 117.93 ? 223 LYS A CG  1 
ATOM 145  C CD  . LYS A 1 133 ? 128.877 114.275 90.942  1.00 117.93 ? 223 LYS A CD  1 
ATOM 146  C CE  . LYS A 1 133 ? 127.661 113.572 90.355  1.00 117.93 ? 223 LYS A CE  1 
ATOM 147  N NZ  . LYS A 1 133 ? 127.121 114.277 89.165  1.00 117.93 ? 223 LYS A NZ  1 
ATOM 148  N N   . SER A 1 134 ? 131.508 118.442 93.539  1.00 109.73 ? 224 SER A N   1 
ATOM 149  C CA  . SER A 1 134 ? 132.314 118.824 94.688  1.00 109.73 ? 224 SER A CA  1 
ATOM 150  C C   . SER A 1 134 ? 131.642 119.923 95.487  1.00 109.73 ? 224 SER A C   1 
ATOM 151  O O   . SER A 1 134 ? 131.531 119.825 96.719  1.00 109.73 ? 224 SER A O   1 
ATOM 152  C CB  . SER A 1 134 ? 133.695 119.296 94.232  1.00 109.73 ? 224 SER A CB  1 
ATOM 153  O OG  . SER A 1 134 ? 133.686 120.688 93.966  1.00 109.73 ? 224 SER A OG  1 
ATOM 154  N N   . THR A 1 135 ? 131.202 120.970 94.798  1.00 109.51 ? 225 THR A N   1 
ATOM 155  C CA  . THR A 1 135 ? 130.493 122.040 95.474  1.00 109.51 ? 225 THR A CA  1 
ATOM 156  C C   . THR A 1 135 ? 129.319 121.488 96.262  1.00 109.51 ? 225 THR A C   1 
ATOM 157  O O   . THR A 1 135 ? 129.123 121.828 97.433  1.00 109.51 ? 225 THR A O   1 
ATOM 158  C CB  . THR A 1 135 ? 130.027 123.060 94.447  1.00 109.51 ? 225 THR A CB  1 
ATOM 159  O OG1 . THR A 1 135 ? 131.060 123.247 93.473  1.00 109.51 ? 225 THR A OG1 1 
ATOM 160  C CG2 . THR A 1 135 ? 129.734 124.377 95.117  1.00 109.51 ? 225 THR A CG2 1 
ATOM 161  N N   . ASP A 1 136 ? 128.554 120.599 95.643  1.00 114.21 ? 226 ASP A N   1 
ATOM 162  C CA  . ASP A 1 136 ? 127.347 120.081 96.266  1.00 114.21 ? 226 ASP A CA  1 
ATOM 163  C C   . ASP A 1 136 ? 127.663 119.301 97.526  1.00 114.21 ? 226 ASP A C   1 
ATOM 164  O O   . ASP A 1 136 ? 126.999 119.474 98.556  1.00 114.21 ? 226 ASP A O   1 
ATOM 165  C CB  . ASP A 1 136 ? 126.600 119.191 95.281  1.00 114.21 ? 226 ASP A CB  1 
ATOM 166  C CG  . ASP A 1 136 ? 125.317 118.654 95.857  1.00 114.21 ? 226 ASP A CG  1 
ATOM 167  O OD1 . ASP A 1 136 ? 125.365 117.577 96.484  1.00 114.21 ? 226 ASP A OD1 1 
ATOM 168  O OD2 . ASP A 1 136 ? 124.262 119.301 95.695  1.00 114.21 ? 226 ASP A OD2 1 
ATOM 169  N N   . GLU A 1 137 ? 128.660 118.424 97.457  1.00 120.85 ? 227 GLU A N   1 
ATOM 170  C CA  . GLU A 1 137 ? 128.965 117.577 98.603  1.00 120.85 ? 227 GLU A CA  1 
ATOM 171  C C   . GLU A 1 137 ? 129.533 118.400 99.751  1.00 120.85 ? 227 GLU A C   1 
ATOM 172  O O   . GLU A 1 137 ? 129.246 118.134 100.922 1.00 120.85 ? 227 GLU A O   1 
ATOM 173  C CB  . GLU A 1 137 ? 129.926 116.461 98.197  1.00 120.85 ? 227 GLU A CB  1 
ATOM 174  C CG  . GLU A 1 137 ? 129.243 115.240 97.583  1.00 120.85 ? 227 GLU A CG  1 
ATOM 175  C CD  . GLU A 1 137 ? 128.540 114.368 98.610  1.00 120.85 ? 227 GLU A CD  1 
ATOM 176  O OE1 . GLU A 1 137 ? 127.858 113.405 98.205  1.00 120.85 ? 227 GLU A OE1 1 
ATOM 177  O OE2 . GLU A 1 137 ? 128.660 114.645 99.821  1.00 120.85 ? 227 GLU A OE2 1 
ATOM 178  N N   . ARG A 1 138 ? 130.335 119.418 99.436  1.00 111.28 ? 228 ARG A N   1 
ATOM 179  C CA  . ARG A 1 138 ? 130.781 120.324 100.490 1.00 111.28 ? 228 ARG A CA  1 
ATOM 180  C C   . ARG A 1 138 ? 129.606 121.072 101.101 1.00 111.28 ? 228 ARG A C   1 
ATOM 181  O O   . ARG A 1 138 ? 129.579 121.328 102.311 1.00 111.28 ? 228 ARG A O   1 
ATOM 182  C CB  . ARG A 1 138 ? 131.814 121.300 99.936  1.00 111.28 ? 228 ARG A CB  1 
ATOM 183  C CG  . ARG A 1 138 ? 133.203 120.716 99.810  1.00 111.28 ? 228 ARG A CG  1 
ATOM 184  C CD  . ARG A 1 138 ? 133.959 121.311 98.639  1.00 111.28 ? 228 ARG A CD  1 
ATOM 185  N NE  . ARG A 1 138 ? 135.396 121.289 98.879  1.00 111.28 ? 228 ARG A NE  1 
ATOM 186  C CZ  . ARG A 1 138 ? 136.125 122.371 99.116  1.00 111.28 ? 228 ARG A CZ  1 
ATOM 187  N NH1 . ARG A 1 138 ? 135.557 123.569 99.125  1.00 111.28 ? 228 ARG A NH1 1 
ATOM 188  N NH2 . ARG A 1 138 ? 137.425 122.256 99.333  1.00 111.28 ? 228 ARG A NH2 1 
ATOM 189  N N   . LEU A 1 139 ? 128.633 121.458 100.277 1.00 106.60 ? 229 LEU A N   1 
ATOM 190  C CA  . LEU A 1 139 ? 127.446 122.098 100.818 1.00 106.60 ? 229 LEU A CA  1 
ATOM 191  C C   . LEU A 1 139 ? 126.722 121.161 101.765 1.00 106.60 ? 229 LEU A C   1 
ATOM 192  O O   . LEU A 1 139 ? 126.250 121.579 102.827 1.00 106.60 ? 229 LEU A O   1 
ATOM 193  C CB  . LEU A 1 139 ? 126.531 122.542 99.688  1.00 106.60 ? 229 LEU A CB  1 
ATOM 194  C CG  . LEU A 1 139 ? 127.171 123.640 98.852  1.00 106.60 ? 229 LEU A CG  1 
ATOM 195  C CD1 . LEU A 1 139 ? 126.489 123.721 97.519  1.00 106.60 ? 229 LEU A CD1 1 
ATOM 196  C CD2 . LEU A 1 139 ? 127.124 124.967 99.565  1.00 106.60 ? 229 LEU A CD2 1 
ATOM 197  N N   . GLU A 1 140 ? 126.642 119.885 101.406 1.00 120.35 ? 230 GLU A N   1 
ATOM 198  C CA  . GLU A 1 140 ? 126.062 118.917 102.327 1.00 120.35 ? 230 GLU A CA  1 
ATOM 199  C C   . GLU A 1 140 ? 126.889 118.807 103.596 1.00 120.35 ? 230 GLU A C   1 
ATOM 200  O O   . GLU A 1 140 ? 126.334 118.601 104.681 1.00 120.35 ? 230 GLU A O   1 
ATOM 201  C CB  . GLU A 1 140 ? 125.943 117.541 101.674 1.00 120.35 ? 230 GLU A CB  1 
ATOM 202  C CG  . GLU A 1 140 ? 125.113 116.565 102.500 1.00 120.35 ? 230 GLU A CG  1 
ATOM 203  C CD  . GLU A 1 140 ? 124.849 115.257 101.787 1.00 120.35 ? 230 GLU A CD  1 
ATOM 204  O OE1 . GLU A 1 140 ? 125.320 115.092 100.645 1.00 120.35 ? 230 GLU A OE1 1 
ATOM 205  O OE2 . GLU A 1 140 ? 124.156 114.397 102.369 1.00 120.35 ? 230 GLU A OE2 1 
ATOM 206  N N   . ASN A 1 141 ? 128.208 118.896 103.461 1.00 119.39 ? 231 ASN A N   1 
ATOM 207  C CA  . ASN A 1 141 ? 129.082 118.937 104.623 1.00 119.39 ? 231 ASN A CA  1 
ATOM 208  C C   . ASN A 1 141 ? 128.679 120.063 105.556 1.00 119.39 ? 231 ASN A C   1 
ATOM 209  O O   . ASN A 1 141 ? 128.552 119.868 106.770 1.00 119.39 ? 231 ASN A O   1 
ATOM 210  C CB  . ASN A 1 141 ? 130.529 119.114 104.175 1.00 119.39 ? 231 ASN A CB  1 
ATOM 211  C CG  . ASN A 1 141 ? 131.322 117.835 104.256 1.00 119.39 ? 231 ASN A CG  1 
ATOM 212  O OD1 . ASN A 1 141 ? 131.736 117.282 103.235 1.00 119.39 ? 231 ASN A OD1 1 
ATOM 213  N ND2 . ASN A 1 141 ? 131.534 117.347 105.476 1.00 119.39 ? 231 ASN A ND2 1 
ATOM 214  N N   . LEU A 1 142 ? 128.470 121.248 104.996 1.00 108.44 ? 232 LEU A N   1 
ATOM 215  C CA  . LEU A 1 142 ? 127.992 122.364 105.799 1.00 108.44 ? 232 LEU A CA  1 
ATOM 216  C C   . LEU A 1 142 ? 126.660 122.023 106.449 1.00 108.44 ? 232 LEU A C   1 
ATOM 217  O O   . LEU A 1 142 ? 126.470 122.228 107.652 1.00 108.44 ? 232 LEU A O   1 
ATOM 218  C CB  . LEU A 1 142 ? 127.881 123.611 104.933 1.00 108.44 ? 232 LEU A CB  1 
ATOM 219  C CG  . LEU A 1 142 ? 129.256 124.180 104.611 1.00 108.44 ? 232 LEU A CG  1 
ATOM 220  C CD1 . LEU A 1 142 ? 129.153 125.080 103.430 1.00 108.44 ? 232 LEU A CD1 1 
ATOM 221  C CD2 . LEU A 1 142 ? 129.807 124.943 105.792 1.00 108.44 ? 232 LEU A CD2 1 
ATOM 222  N N   . LEU A 1 143 ? 125.729 121.486 105.661 1.00 115.09 ? 233 LEU A N   1 
ATOM 223  C CA  . LEU A 1 143 ? 124.408 121.167 106.186 1.00 115.09 ? 233 LEU A CA  1 
ATOM 224  C C   . LEU A 1 143 ? 124.482 120.273 107.409 1.00 115.09 ? 233 LEU A C   1 
ATOM 225  O O   . LEU A 1 143 ? 123.986 120.640 108.481 1.00 115.09 ? 233 LEU A O   1 
ATOM 226  C CB  . LEU A 1 143 ? 123.557 120.499 105.113 1.00 115.09 ? 233 LEU A CB  1 
ATOM 227  C CG  . LEU A 1 143 ? 122.933 121.423 104.067 1.00 115.09 ? 233 LEU A CG  1 
ATOM 228  C CD1 . LEU A 1 143 ? 121.473 121.059 103.912 1.00 115.09 ? 233 LEU A CD1 1 
ATOM 229  C CD2 . LEU A 1 143 ? 123.074 122.883 104.442 1.00 115.09 ? 233 LEU A CD2 1 
ATOM 230  N N   . ASN A 1 144 ? 125.113 119.109 107.284 1.00 122.15 ? 234 ASN A N   1 
ATOM 231  C CA  . ASN A 1 144 ? 125.067 118.193 108.414 1.00 122.15 ? 234 ASN A CA  1 
ATOM 232  C C   . ASN A 1 144 ? 125.913 118.710 109.569 1.00 122.15 ? 234 ASN A C   1 
ATOM 233  O O   . ASN A 1 144 ? 125.537 118.535 110.733 1.00 122.15 ? 234 ASN A O   1 
ATOM 234  C CB  . ASN A 1 144 ? 125.488 116.769 108.027 1.00 122.15 ? 234 ASN A CB  1 
ATOM 235  C CG  . ASN A 1 144 ? 126.777 116.718 107.250 1.00 122.15 ? 234 ASN A CG  1 
ATOM 236  O OD1 . ASN A 1 144 ? 127.360 117.740 106.942 1.00 122.15 ? 234 ASN A OD1 1 
ATOM 237  N ND2 . ASN A 1 144 ? 127.230 115.513 106.932 1.00 122.15 ? 234 ASN A ND2 1 
ATOM 238  N N   . ILE A 1 145 ? 127.043 119.369 109.284 1.00 109.01 ? 235 ILE A N   1 
ATOM 239  C CA  . ILE A 1 145 ? 127.863 119.828 110.395 1.00 109.01 ? 235 ILE A CA  1 
ATOM 240  C C   . ILE A 1 145 ? 127.105 120.860 111.212 1.00 109.01 ? 235 ILE A C   1 
ATOM 241  O O   . ILE A 1 145 ? 127.095 120.805 112.450 1.00 109.01 ? 235 ILE A O   1 
ATOM 242  C CB  . ILE A 1 145 ? 129.225 120.351 109.903 1.00 109.01 ? 235 ILE A CB  1 
ATOM 243  C CG1 . ILE A 1 145 ? 130.200 120.424 111.077 1.00 109.01 ? 235 ILE A CG1 1 
ATOM 244  C CG2 . ILE A 1 145 ? 129.108 121.715 109.251 1.00 109.01 ? 235 ILE A CG2 1 
ATOM 245  C CD1 . ILE A 1 145 ? 131.628 120.642 110.669 1.00 109.01 ? 235 ILE A CD1 1 
ATOM 246  N N   . VAL A 1 146 ? 126.396 121.766 110.548 1.00 106.98 ? 236 VAL A N   1 
ATOM 247  C CA  . VAL A 1 146 ? 125.663 122.763 111.307 1.00 106.98 ? 236 VAL A CA  1 
ATOM 248  C C   . VAL A 1 146 ? 124.448 122.131 111.967 1.00 106.98 ? 236 VAL A C   1 
ATOM 249  O O   . VAL A 1 146 ? 123.992 122.590 113.019 1.00 106.98 ? 236 VAL A O   1 
ATOM 250  C CB  . VAL A 1 146 ? 125.297 123.956 110.412 1.00 106.98 ? 236 VAL A CB  1 
ATOM 251  C CG1 . VAL A 1 146 ? 126.547 124.486 109.756 1.00 106.98 ? 236 VAL A CG1 1 
ATOM 252  C CG2 . VAL A 1 146 ? 124.297 123.544 109.376 1.00 106.98 ? 236 VAL A CG2 1 
ATOM 253  N N   . ARG A 1 147 ? 123.921 121.050 111.388 1.00 115.88 ? 237 ARG A N   1 
ATOM 254  C CA  . ARG A 1 147 ? 122.885 120.315 112.106 1.00 115.88 ? 237 ARG A CA  1 
ATOM 255  C C   . ARG A 1 147 ? 123.405 119.805 113.441 1.00 115.88 ? 237 ARG A C   1 
ATOM 256  O O   . ARG A 1 147 ? 122.771 120.016 114.486 1.00 115.88 ? 237 ARG A O   1 
ATOM 257  C CB  . ARG A 1 147 ? 122.365 119.151 111.270 1.00 115.88 ? 237 ARG A CB  1 
ATOM 258  C CG  . ARG A 1 147 ? 121.173 119.479 110.412 1.00 115.88 ? 237 ARG A CG  1 
ATOM 259  C CD  . ARG A 1 147 ? 120.734 118.241 109.682 1.00 115.88 ? 237 ARG A CD  1 
ATOM 260  N NE  . ARG A 1 147 ? 119.741 118.546 108.669 1.00 115.88 ? 237 ARG A NE  1 
ATOM 261  C CZ  . ARG A 1 147 ? 119.892 118.269 107.381 1.00 115.88 ? 237 ARG A CZ  1 
ATOM 262  N NH1 . ARG A 1 147 ? 120.999 117.677 106.956 1.00 115.88 ? 237 ARG A NH1 1 
ATOM 263  N NH2 . ARG A 1 147 ? 118.936 118.586 106.521 1.00 115.88 ? 237 ARG A NH2 1 
ATOM 264  N N   . GLU A 1 148 ? 124.547 119.116 113.421 1.00 106.91 ? 238 GLU A N   1 
ATOM 265  C CA  . GLU A 1 148 ? 125.104 118.634 114.676 1.00 106.91 ? 238 GLU A CA  1 
ATOM 266  C C   . GLU A 1 148 ? 125.361 119.780 115.631 1.00 106.91 ? 238 GLU A C   1 
ATOM 267  O O   . GLU A 1 148 ? 125.157 119.637 116.839 1.00 106.91 ? 238 GLU A O   1 
ATOM 268  C CB  . GLU A 1 148 ? 126.398 117.847 114.468 1.00 106.91 ? 238 GLU A CB  1 
ATOM 269  C CG  . GLU A 1 148 ? 126.220 116.488 113.828 1.00 106.91 ? 238 GLU A CG  1 
ATOM 270  C CD  . GLU A 1 148 ? 126.660 116.451 112.386 1.00 106.91 ? 238 GLU A CD  1 
ATOM 271  O OE1 . GLU A 1 148 ? 127.432 117.343 111.994 1.00 106.91 ? 238 GLU A OE1 1 
ATOM 272  O OE2 . GLU A 1 148 ? 126.238 115.538 111.645 1.00 106.91 ? 238 GLU A OE2 1 
ATOM 273  N N   . ILE A 1 149 ? 125.818 120.916 115.114 1.00 90.81  ? 239 ILE A N   1 
ATOM 274  C CA  . ILE A 1 149 ? 126.072 122.050 115.992 1.00 90.81  ? 239 ILE A CA  1 
ATOM 275  C C   . ILE A 1 149 ? 124.779 122.505 116.651 1.00 90.81  ? 239 ILE A C   1 
ATOM 276  O O   . ILE A 1 149 ? 124.740 122.781 117.855 1.00 90.81  ? 239 ILE A O   1 
ATOM 277  C CB  . ILE A 1 149 ? 126.745 123.190 115.219 1.00 90.81  ? 239 ILE A CB  1 
ATOM 278  C CG1 . ILE A 1 149 ? 128.181 122.811 114.902 1.00 90.81  ? 239 ILE A CG1 1 
ATOM 279  C CG2 . ILE A 1 149 ? 126.743 124.444 116.047 1.00 90.81  ? 239 ILE A CG2 1 
ATOM 280  C CD1 . ILE A 1 149 ? 128.990 123.950 114.390 1.00 90.81  ? 239 ILE A CD1 1 
ATOM 281  N N   . LEU A 1 150 ? 123.702 122.590 115.873 1.00 89.67  ? 240 LEU A N   1 
ATOM 282  C CA  . LEU A 1 150 ? 122.428 122.992 116.451 1.00 89.67  ? 240 LEU A CA  1 
ATOM 283  C C   . LEU A 1 150 ? 121.996 122.027 117.535 1.00 89.67  ? 240 LEU A C   1 
ATOM 284  O O   . LEU A 1 150 ? 121.525 122.452 118.597 1.00 89.67  ? 240 LEU A O   1 
ATOM 285  C CB  . LEU A 1 150 ? 121.355 123.091 115.369 1.00 89.67  ? 240 LEU A CB  1 
ATOM 286  C CG  . LEU A 1 150 ? 119.987 123.621 115.810 1.00 89.67  ? 240 LEU A CG  1 
ATOM 287  C CD1 . LEU A 1 150 ? 119.371 124.494 114.735 1.00 89.67  ? 240 LEU A CD1 1 
ATOM 288  C CD2 . LEU A 1 150 ? 119.043 122.480 116.138 1.00 89.67  ? 240 LEU A CD2 1 
ATOM 289  N N   . ASP A 1 151 ? 122.159 120.729 117.295 1.00 102.49 ? 241 ASP A N   1 
ATOM 290  C CA  . ASP A 1 151 ? 121.762 119.755 118.305 1.00 102.49 ? 241 ASP A CA  1 
ATOM 291  C C   . ASP A 1 151 ? 122.616 119.892 119.561 1.00 102.49 ? 241 ASP A C   1 
ATOM 292  O O   . ASP A 1 151 ? 122.106 119.828 120.689 1.00 102.49 ? 241 ASP A O   1 
ATOM 293  C CB  . ASP A 1 151 ? 121.858 118.342 117.736 1.00 102.49 ? 241 ASP A CB  1 
ATOM 294  C CG  . ASP A 1 151 ? 121.177 117.318 118.616 1.00 102.49 ? 241 ASP A CG  1 
ATOM 295  O OD1 . ASP A 1 151 ? 120.146 117.658 119.230 1.00 102.49 ? 241 ASP A OD1 1 
ATOM 296  O OD2 . ASP A 1 151 ? 121.670 116.174 118.692 1.00 102.49 ? 241 ASP A OD2 1 
ATOM 297  N N   . VAL A 1 152 ? 123.923 120.076 119.379 1.00 91.85  ? 242 VAL A N   1 
ATOM 298  C CA  . VAL A 1 152 ? 124.825 120.212 120.515 1.00 91.85  ? 242 VAL A CA  1 
ATOM 299  C C   . VAL A 1 152 ? 124.458 121.436 121.333 1.00 91.85  ? 242 VAL A C   1 
ATOM 300  O O   . VAL A 1 152 ? 124.496 121.410 122.567 1.00 91.85  ? 242 VAL A O   1 
ATOM 301  C CB  . VAL A 1 152 ? 126.283 120.261 120.030 1.00 91.85  ? 242 VAL A CB  1 
ATOM 302  C CG1 . VAL A 1 152 ? 127.171 120.867 121.085 1.00 91.85  ? 242 VAL A CG1 1 
ATOM 303  C CG2 . VAL A 1 152 ? 126.762 118.867 119.693 1.00 91.85  ? 242 VAL A CG2 1 
ATOM 304  N N   . GLN A 1 153 ? 124.074 122.519 120.666 1.00 89.67  ? 243 GLN A N   1 
ATOM 305  C CA  . GLN A 1 153 ? 123.692 123.718 121.398 1.00 89.67  ? 243 GLN A CA  1 
ATOM 306  C C   . GLN A 1 153 ? 122.373 123.519 122.125 1.00 89.67  ? 243 GLN A C   1 
ATOM 307  O O   . GLN A 1 153 ? 122.201 123.990 123.255 1.00 89.67  ? 243 GLN A O   1 
ATOM 308  C CB  . GLN A 1 153 ? 123.617 124.908 120.451 1.00 89.67  ? 243 GLN A CB  1 
ATOM 309  C CG  . GLN A 1 153 ? 124.977 125.359 119.974 1.00 89.67  ? 243 GLN A CG  1 
ATOM 310  C CD  . GLN A 1 153 ? 126.048 125.138 121.019 1.00 89.67  ? 243 GLN A CD  1 
ATOM 311  O OE1 . GLN A 1 153 ? 126.736 124.117 121.022 1.00 89.67  ? 243 GLN A OE1 1 
ATOM 312  N NE2 . GLN A 1 153 ? 126.178 126.087 121.929 1.00 89.67  ? 243 GLN A NE2 1 
ATOM 313  N N   . ARG A 1 154 ? 121.426 122.832 121.491 1.00 96.97  ? 244 ARG A N   1 
ATOM 314  C CA  . ARG A 1 154 ? 120.213 122.439 122.195 1.00 96.97  ? 244 ARG A CA  1 
ATOM 315  C C   . ARG A 1 154 ? 120.547 121.730 123.499 1.00 96.97  ? 244 ARG A C   1 
ATOM 316  O O   . ARG A 1 154 ? 120.085 122.130 124.580 1.00 96.97  ? 244 ARG A O   1 
ATOM 317  C CB  . ARG A 1 154 ? 119.372 121.536 121.299 1.00 96.97  ? 244 ARG A CB  1 
ATOM 318  C CG  . ARG A 1 154 ? 118.333 120.727 122.044 1.00 96.97  ? 244 ARG A CG  1 
ATOM 319  C CD  . ARG A 1 154 ? 117.551 119.829 121.101 1.00 96.97  ? 244 ARG A CD  1 
ATOM 320  N NE  . ARG A 1 154 ? 116.888 120.578 120.038 1.00 96.97  ? 244 ARG A NE  1 
ATOM 321  C CZ  . ARG A 1 154 ? 117.279 120.586 118.768 1.00 96.97  ? 244 ARG A CZ  1 
ATOM 322  N NH1 . ARG A 1 154 ? 118.338 119.883 118.392 1.00 96.97  ? 244 ARG A NH1 1 
ATOM 323  N NH2 . ARG A 1 154 ? 116.609 121.298 117.873 1.00 96.97  ? 244 ARG A NH2 1 
ATOM 324  N N   . ASP A 1 155 ? 121.368 120.691 123.419 1.00 96.37  ? 245 ASP A N   1 
ATOM 325  C CA  . ASP A 1 155 ? 121.672 119.905 124.603 1.00 96.37  ? 245 ASP A CA  1 
ATOM 326  C C   . ASP A 1 155 ? 122.480 120.680 125.637 1.00 96.37  ? 245 ASP A C   1 
ATOM 327  O O   . ASP A 1 155 ? 122.267 120.491 126.840 1.00 96.37  ? 245 ASP A O   1 
ATOM 328  C CB  . ASP A 1 155 ? 122.417 118.628 124.214 1.00 96.37  ? 245 ASP A CB  1 
ATOM 329  C CG  . ASP A 1 155 ? 122.299 117.557 125.269 1.00 96.37  ? 245 ASP A CG  1 
ATOM 330  O OD1 . ASP A 1 155 ? 121.241 116.901 125.332 1.00 96.37  ? 245 ASP A OD1 1 
ATOM 331  O OD2 . ASP A 1 155 ? 123.256 117.384 126.049 1.00 96.37  ? 245 ASP A OD2 1 
ATOM 332  N N   . MET A 1 156 ? 123.384 121.556 125.206 1.00 80.54  ? 246 MET A N   1 
ATOM 333  C CA  . MET A 1 156 ? 124.054 122.422 126.164 1.00 80.54  ? 246 MET A CA  1 
ATOM 334  C C   . MET A 1 156 ? 123.059 123.316 126.874 1.00 80.54  ? 246 MET A C   1 
ATOM 335  O O   . MET A 1 156 ? 123.172 123.538 128.080 1.00 80.54  ? 246 MET A O   1 
ATOM 336  C CB  . MET A 1 156 ? 125.118 123.274 125.482 1.00 80.54  ? 246 MET A CB  1 
ATOM 337  C CG  . MET A 1 156 ? 126.445 122.590 125.305 1.00 80.54  ? 246 MET A CG  1 
ATOM 338  S SD  . MET A 1 156 ? 127.704 123.778 124.821 1.00 80.54  ? 246 MET A SD  1 
ATOM 339  C CE  . MET A 1 156 ? 127.837 124.740 126.322 1.00 80.54  ? 246 MET A CE  1 
ATOM 340  N N   . ARG A 1 157 ? 122.102 123.875 126.138 1.00 76.59  ? 247 ARG A N   1 
ATOM 341  C CA  . ARG A 1 157 ? 121.099 124.696 126.793 1.00 76.59  ? 247 ARG A CA  1 
ATOM 342  C C   . ARG A 1 157 ? 120.364 123.899 127.852 1.00 76.59  ? 247 ARG A C   1 
ATOM 343  O O   . ARG A 1 157 ? 120.112 124.398 128.957 1.00 76.59  ? 247 ARG A O   1 
ATOM 344  C CB  . ARG A 1 157 ? 120.115 125.253 125.777 1.00 76.59  ? 247 ARG A CB  1 
ATOM 345  C CG  . ARG A 1 157 ? 118.754 125.464 126.379 1.00 76.59  ? 247 ARG A CG  1 
ATOM 346  C CD  . ARG A 1 157 ? 117.879 126.284 125.491 1.00 76.59  ? 247 ARG A CD  1 
ATOM 347  N NE  . ARG A 1 157 ? 118.045 127.703 125.753 1.00 76.59  ? 247 ARG A NE  1 
ATOM 348  C CZ  . ARG A 1 157 ? 117.167 128.628 125.390 1.00 76.59  ? 247 ARG A CZ  1 
ATOM 349  N NH1 . ARG A 1 157 ? 116.060 128.283 124.750 1.00 76.59  ? 247 ARG A NH1 1 
ATOM 350  N NH2 . ARG A 1 157 ? 117.397 129.899 125.664 1.00 76.59  ? 247 ARG A NH2 1 
ATOM 351  N N   . ASN A 1 158 ? 120.016 122.654 127.536 1.00 84.87  ? 248 ASN A N   1 
ATOM 352  C CA  . ASN A 1 158 ? 119.361 121.812 128.533 1.00 84.87  ? 248 ASN A CA  1 
ATOM 353  C C   . ASN A 1 158 ? 120.263 121.606 129.745 1.00 84.87  ? 248 ASN A C   1 
ATOM 354  O O   . ASN A 1 158 ? 119.816 121.684 130.898 1.00 84.87  ? 248 ASN A O   1 
ATOM 355  C CB  . ASN A 1 158 ? 118.966 120.476 127.915 1.00 84.87  ? 248 ASN A CB  1 
ATOM 356  C CG  . ASN A 1 158 ? 117.754 120.593 127.023 1.00 84.87  ? 248 ASN A CG  1 
ATOM 357  O OD1 . ASN A 1 158 ? 116.866 121.406 127.273 1.00 84.87  ? 248 ASN A OD1 1 
ATOM 358  N ND2 . ASN A 1 158 ? 117.709 119.785 125.971 1.00 84.87  ? 248 ASN A ND2 1 
ATOM 359  N N   . ASP A 1 159 ? 121.546 121.358 129.498 1.00 70.67  ? 249 ASP A N   1 
ATOM 360  C CA  . ASP A 1 159 ? 122.489 121.170 130.590 1.00 70.67  ? 249 ASP A CA  1 
ATOM 361  C C   . ASP A 1 159 ? 122.566 122.408 131.475 1.00 70.67  ? 249 ASP A C   1 
ATOM 362  O O   . ASP A 1 159 ? 122.600 122.301 132.706 1.00 70.67  ? 249 ASP A O   1 
ATOM 363  C CB  . ASP A 1 159 ? 123.857 120.830 130.012 1.00 70.67  ? 249 ASP A CB  1 
ATOM 364  C CG  . ASP A 1 159 ? 124.757 120.141 131.007 1.00 70.67  ? 249 ASP A CG  1 
ATOM 365  O OD1 . ASP A 1 159 ? 124.469 118.978 131.349 1.00 70.67  ? 249 ASP A OD1 1 
ATOM 366  O OD2 . ASP A 1 159 ? 125.761 120.745 131.430 1.00 70.67  ? 249 ASP A OD2 1 
ATOM 367  N N   . LEU A 1 160 ? 122.569 123.587 130.864 1.00 60.83  ? 250 LEU A N   1 
ATOM 368  C CA  . LEU A 1 160 ? 122.687 124.816 131.634 1.00 60.83  ? 250 LEU A CA  1 
ATOM 369  C C   . LEU A 1 160 ? 121.435 125.062 132.456 1.00 60.83  ? 250 LEU A C   1 
ATOM 370  O O   . LEU A 1 160 ? 121.518 125.505 133.606 1.00 60.83  ? 250 LEU A O   1 
ATOM 371  C CB  . LEU A 1 160 ? 122.957 125.990 130.706 1.00 60.83  ? 250 LEU A CB  1 
ATOM 372  C CG  . LEU A 1 160 ? 123.762 127.079 131.382 1.00 60.83  ? 250 LEU A CG  1 
ATOM 373  C CD1 . LEU A 1 160 ? 125.055 126.482 131.851 1.00 60.83  ? 250 LEU A CD1 1 
ATOM 374  C CD2 . LEU A 1 160 ? 124.028 128.188 130.415 1.00 60.83  ? 250 LEU A CD2 1 
ATOM 375  N N   . SER A 1 161 ? 120.264 124.807 131.876 1.00 71.88  ? 251 SER A N   1 
ATOM 376  C CA  . SER A 1 161 ? 119.048 124.832 132.676 1.00 71.88  ? 251 SER A CA  1 
ATOM 377  C C   . SER A 1 161 ? 119.170 123.920 133.883 1.00 71.88  ? 251 SER A C   1 
ATOM 378  O O   . SER A 1 161 ? 118.801 124.307 135.005 1.00 71.88  ? 251 SER A O   1 
ATOM 379  C CB  . SER A 1 161 ? 117.850 124.415 131.829 1.00 71.88  ? 251 SER A CB  1 
ATOM 380  O OG  . SER A 1 161 ? 116.678 124.316 132.620 1.00 71.88  ? 251 SER A OG  1 
ATOM 381  N N   . ASN A 1 162 ? 119.678 122.708 133.668 1.00 68.82  ? 252 ASN A N   1 
ATOM 382  C CA  . ASN A 1 162 ? 119.889 121.793 134.777 1.00 68.82  ? 252 ASN A CA  1 
ATOM 383  C C   . ASN A 1 162 ? 120.752 122.446 135.849 1.00 68.82  ? 252 ASN A C   1 
ATOM 384  O O   . ASN A 1 162 ? 120.412 122.432 137.042 1.00 68.82  ? 252 ASN A O   1 
ATOM 385  C CB  . ASN A 1 162 ? 120.538 120.510 134.266 1.00 68.82  ? 252 ASN A CB  1 
ATOM 386  C CG  . ASN A 1 162 ? 120.067 119.282 135.008 1.00 68.82  ? 252 ASN A CG  1 
ATOM 387  O OD1 . ASN A 1 162 ? 119.091 119.334 135.752 1.00 68.82  ? 252 ASN A OD1 1 
ATOM 388  N ND2 . ASN A 1 162 ? 120.766 118.170 134.820 1.00 68.82  ? 252 ASN A ND2 1 
ATOM 389  N N   . LEU A 1 163 ? 121.858 123.053 135.434 1.00 53.09  ? 253 LEU A N   1 
ATOM 390  C CA  . LEU A 1 163 ? 122.781 123.605 136.414 1.00 53.09  ? 253 LEU A CA  1 
ATOM 391  C C   . LEU A 1 163 ? 122.137 124.758 137.172 1.00 53.09  ? 253 LEU A C   1 
ATOM 392  O O   . LEU A 1 163 ? 122.381 124.939 138.371 1.00 53.09  ? 253 LEU A O   1 
ATOM 393  C CB  . LEU A 1 163 ? 124.067 124.063 135.735 1.00 53.09  ? 253 LEU A CB  1 
ATOM 394  C CG  . LEU A 1 163 ? 125.234 124.264 136.698 1.00 53.09  ? 253 LEU A CG  1 
ATOM 395  C CD1 . LEU A 1 163 ? 125.714 122.915 137.182 1.00 53.09  ? 253 LEU A CD1 1 
ATOM 396  C CD2 . LEU A 1 163 ? 126.359 125.010 136.062 1.00 53.09  ? 253 LEU A CD2 1 
ATOM 397  N N   . THR A 1 164 ? 121.307 125.548 136.491 1.00 49.52  ? 254 THR A N   1 
ATOM 398  C CA  . THR A 1 164 ? 120.640 126.660 137.159 1.00 49.52  ? 254 THR A CA  1 
ATOM 399  C C   . THR A 1 164 ? 119.710 126.152 138.243 1.00 49.52  ? 254 THR A C   1 
ATOM 400  O O   . THR A 1 164 ? 119.743 126.630 139.388 1.00 49.52  ? 254 THR A O   1 
ATOM 401  C CB  . THR A 1 164 ? 119.857 127.495 136.159 1.00 49.52  ? 254 THR A CB  1 
ATOM 402  O OG1 . THR A 1 164 ? 120.721 127.887 135.096 1.00 49.52  ? 254 THR A OG1 1 
ATOM 403  C CG2 . THR A 1 164 ? 119.326 128.731 136.829 1.00 49.52  ? 254 THR A CG2 1 
ATOM 404  N N   . ARG A 1 165 ? 118.848 125.202 137.889 1.00 60.46  ? 255 ARG A N   1 
ATOM 405  C CA  . ARG A 1 165 ? 118.018 124.600 138.917 1.00 60.46  ? 255 ARG A CA  1 
ATOM 406  C C   . ARG A 1 165 ? 118.851 124.118 140.085 1.00 60.46  ? 255 ARG A C   1 
ATOM 407  O O   . ARG A 1 165 ? 118.493 124.388 141.236 1.00 60.46  ? 255 ARG A O   1 
ATOM 408  C CB  . ARG A 1 165 ? 117.207 123.434 138.370 1.00 60.46  ? 255 ARG A CB  1 
ATOM 409  C CG  . ARG A 1 165 ? 116.017 123.838 137.540 1.00 60.46  ? 255 ARG A CG  1 
ATOM 410  C CD  . ARG A 1 165 ? 115.157 122.629 137.216 1.00 60.46  ? 255 ARG A CD  1 
ATOM 411  N NE  . ARG A 1 165 ? 115.916 121.596 136.517 1.00 60.46  ? 255 ARG A NE  1 
ATOM 412  C CZ  . ARG A 1 165 ? 116.128 121.579 135.206 1.00 60.46  ? 255 ARG A CZ  1 
ATOM 413  N NH1 . ARG A 1 165 ? 115.642 122.544 134.439 1.00 60.46  ? 255 ARG A NH1 1 
ATOM 414  N NH2 . ARG A 1 165 ? 116.834 120.600 134.664 1.00 60.46  ? 255 ARG A NH2 1 
ATOM 415  N N   . LYS A 1 166 ? 119.968 123.443 139.819 1.00 50.74  ? 256 LYS A N   1 
ATOM 416  C CA  . LYS A 1 166 ? 120.721 122.871 140.928 1.00 50.74  ? 256 LYS A CA  1 
ATOM 417  C C   . LYS A 1 166 ? 121.325 123.944 141.825 1.00 50.74  ? 256 LYS A C   1 
ATOM 418  O O   . LYS A 1 166 ? 121.299 123.816 143.059 1.00 50.74  ? 256 LYS A O   1 
ATOM 419  C CB  . LYS A 1 166 ? 121.804 121.940 140.411 1.00 50.74  ? 256 LYS A CB  1 
ATOM 420  C CG  . LYS A 1 166 ? 121.526 120.518 140.772 1.00 50.74  ? 256 LYS A CG  1 
ATOM 421  C CD  . LYS A 1 166 ? 122.571 119.616 140.201 1.00 50.74  ? 256 LYS A CD  1 
ATOM 422  C CE  . LYS A 1 166 ? 122.118 118.180 140.266 1.00 50.74  ? 256 LYS A CE  1 
ATOM 423  N NZ  . LYS A 1 166 ? 123.068 117.279 139.564 1.00 50.74  ? 256 LYS A NZ  1 
ATOM 424  N N   . VAL A 1 167 ? 121.864 125.010 141.241 1.00 40.93  ? 257 VAL A N   1 
ATOM 425  C CA  . VAL A 1 167 ? 122.452 126.049 142.077 1.00 40.93  ? 257 VAL A CA  1 
ATOM 426  C C   . VAL A 1 167 ? 121.384 126.701 142.936 1.00 40.93  ? 257 VAL A C   1 
ATOM 427  O O   . VAL A 1 167 ? 121.584 126.926 144.137 1.00 40.93  ? 257 VAL A O   1 
ATOM 428  C CB  . VAL A 1 167 ? 123.199 127.078 141.219 1.00 40.93  ? 257 VAL A CB  1 
ATOM 429  C CG1 . VAL A 1 167 ? 123.377 128.350 141.991 1.00 40.93  ? 257 VAL A CG1 1 
ATOM 430  C CG2 . VAL A 1 167 ? 124.540 126.533 140.835 1.00 40.93  ? 257 VAL A CG2 1 
ATOM 431  N N   . ASP A 1 168 ? 120.222 126.991 142.356 1.00 42.24  ? 258 ASP A N   1 
ATOM 432  C CA  . ASP A 1 168 ? 119.181 127.606 143.167 1.00 42.24  ? 258 ASP A CA  1 
ATOM 433  C C   . ASP A 1 168 ? 118.754 126.693 144.303 1.00 42.24  ? 258 ASP A C   1 
ATOM 434  O O   . ASP A 1 168 ? 118.580 127.142 145.446 1.00 42.24  ? 258 ASP A O   1 
ATOM 435  C CB  . ASP A 1 168 ? 117.989 127.973 142.304 1.00 42.24  ? 258 ASP A CB  1 
ATOM 436  C CG  . ASP A 1 168 ? 117.970 129.429 141.968 1.00 42.24  ? 258 ASP A CG  1 
ATOM 437  O OD1 . ASP A 1 168 ? 118.877 130.132 142.445 1.00 42.24  ? 258 ASP A OD1 1 
ATOM 438  O OD2 . ASP A 1 168 ? 117.057 129.875 141.244 1.00 42.24  ? 258 ASP A OD2 1 
ATOM 439  N N   . ARG A 1 169 ? 118.548 125.416 143.997 1.00 47.42  ? 259 ARG A N   1 
ATOM 440  C CA  . ARG A 1 169 ? 118.257 124.444 145.038 1.00 47.42  ? 259 ARG A CA  1 
ATOM 441  C C   . ARG A 1 169 ? 119.232 124.572 146.196 1.00 47.42  ? 259 ARG A C   1 
ATOM 442  O O   . ARG A 1 169 ? 118.826 124.794 147.345 1.00 47.42  ? 259 ARG A O   1 
ATOM 443  C CB  . ARG A 1 169 ? 118.320 123.041 144.454 1.00 47.42  ? 259 ARG A CB  1 
ATOM 444  C CG  . ARG A 1 169 ? 118.360 121.955 145.478 1.00 47.42  ? 259 ARG A CG  1 
ATOM 445  C CD  . ARG A 1 169 ? 116.978 121.698 145.919 1.00 47.42  ? 259 ARG A CD  1 
ATOM 446  N NE  . ARG A 1 169 ? 116.217 121.131 144.825 1.00 47.42  ? 259 ARG A NE  1 
ATOM 447  C CZ  . ARG A 1 169 ? 114.894 121.104 144.790 1.00 47.42  ? 259 ARG A CZ  1 
ATOM 448  N NH1 . ARG A 1 169 ? 114.200 121.627 145.787 1.00 47.42  ? 259 ARG A NH1 1 
ATOM 449  N NH2 . ARG A 1 169 ? 114.267 120.565 143.759 1.00 47.42  ? 259 ARG A NH2 1 
ATOM 450  N N   . MET A 1 170 ? 120.524 124.457 145.906 1.00 41.59  ? 260 MET A N   1 
ATOM 451  C CA  . MET A 1 170 ? 121.506 124.490 146.981 1.00 41.59  ? 260 MET A CA  1 
ATOM 452  C C   . MET A 1 170 ? 121.420 125.797 147.756 1.00 41.59  ? 260 MET A C   1 
ATOM 453  O O   . MET A 1 170 ? 121.629 125.828 148.975 1.00 41.59  ? 260 MET A O   1 
ATOM 454  C CB  . MET A 1 170 ? 122.906 124.283 146.415 1.00 41.59  ? 260 MET A CB  1 
ATOM 455  C CG  . MET A 1 170 ? 123.972 124.190 147.466 1.00 41.59  ? 260 MET A CG  1 
ATOM 456  S SD  . MET A 1 170 ? 125.570 124.027 146.701 1.00 41.59  ? 260 MET A SD  1 
ATOM 457  C CE  . MET A 1 170 ? 125.571 125.543 145.775 1.00 41.59  ? 260 MET A CE  1 
ATOM 458  N N   . ASP A 1 171 ? 121.116 126.892 147.059 1.00 41.76  ? 261 ASP A N   1 
ATOM 459  C CA  . ASP A 1 171 ? 120.979 128.168 147.748 1.00 41.76  ? 261 ASP A CA  1 
ATOM 460  C C   . ASP A 1 171 ? 119.910 128.086 148.818 1.00 41.76  ? 261 ASP A C   1 
ATOM 461  O O   . ASP A 1 171 ? 120.139 128.461 149.979 1.00 41.76  ? 261 ASP A O   1 
ATOM 462  C CB  . ASP A 1 171 ? 120.641 129.265 146.747 1.00 41.76  ? 261 ASP A CB  1 
ATOM 463  C CG  . ASP A 1 171 ? 120.689 130.641 147.360 1.00 41.76  ? 261 ASP A CG  1 
ATOM 464  O OD1 . ASP A 1 171 ? 121.050 130.747 148.544 1.00 41.76  ? 261 ASP A OD1 1 
ATOM 465  O OD2 . ASP A 1 171 ? 120.375 131.622 146.658 1.00 41.76  ? 261 ASP A OD2 1 
ATOM 466  N N   . MET A 1 172 ? 118.728 127.619 148.432 1.00 40.99  ? 262 MET A N   1 
ATOM 467  C CA  . MET A 1 172 ? 117.668 127.445 149.414 1.00 40.99  ? 262 MET A CA  1 
ATOM 468  C C   . MET A 1 172 ? 118.157 126.597 150.573 1.00 40.99  ? 262 MET A C   1 
ATOM 469  O O   . MET A 1 172 ? 117.932 126.931 151.745 1.00 40.99  ? 262 MET A O   1 
ATOM 470  C CB  . MET A 1 172 ? 116.442 126.809 148.769 1.00 40.99  ? 262 MET A CB  1 
ATOM 471  C CG  . MET A 1 172 ? 115.264 126.691 149.695 1.00 40.99  ? 262 MET A CG  1 
ATOM 472  S SD  . MET A 1 172 ? 115.245 125.168 150.649 1.00 40.99  ? 262 MET A SD  1 
ATOM 473  C CE  . MET A 1 172 ? 114.524 124.050 149.468 1.00 40.99  ? 262 MET A CE  1 
ATOM 474  N N   . ARG A 1 173 ? 118.849 125.499 150.260 1.00 48.95  ? 263 ARG A N   1 
ATOM 475  C CA  . ARG A 1 173 ? 119.253 124.565 151.308 1.00 48.95  ? 263 ARG A CA  1 
ATOM 476  C C   . ARG A 1 173 ? 120.137 125.245 152.340 1.00 48.95  ? 263 ARG A C   1 
ATOM 477  O O   . ARG A 1 173 ? 119.906 125.131 153.551 1.00 48.95  ? 263 ARG A O   1 
ATOM 478  C CB  . ARG A 1 173 ? 119.982 123.360 150.718 1.00 48.95  ? 263 ARG A CB  1 
ATOM 479  C CG  . ARG A 1 173 ? 120.346 122.339 151.777 1.00 48.95  ? 263 ARG A CG  1 
ATOM 480  C CD  . ARG A 1 173 ? 121.176 121.207 151.237 1.00 48.95  ? 263 ARG A CD  1 
ATOM 481  N NE  . ARG A 1 173 ? 120.669 120.717 149.967 1.00 48.95  ? 263 ARG A NE  1 
ATOM 482  C CZ  . ARG A 1 173 ? 119.696 119.825 149.855 1.00 48.95  ? 263 ARG A CZ  1 
ATOM 483  N NH1 . ARG A 1 173 ? 119.123 119.336 150.940 1.00 48.95  ? 263 ARG A NH1 1 
ATOM 484  N NH2 . ARG A 1 173 ? 119.297 119.428 148.659 1.00 48.95  ? 263 ARG A NH2 1 
ATOM 485  N N   . LEU A 1 174 ? 121.158 125.956 151.877 1.00 49.18  ? 264 LEU A N   1 
ATOM 486  C CA  . LEU A 1 174 ? 122.085 126.537 152.835 1.00 49.18  ? 264 LEU A CA  1 
ATOM 487  C C   . LEU A 1 174 ? 121.447 127.666 153.618 1.00 49.18  ? 264 LEU A C   1 
ATOM 488  O O   . LEU A 1 174 ? 121.670 127.778 154.829 1.00 49.18  ? 264 LEU A O   1 
ATOM 489  C CB  . LEU A 1 174 ? 123.355 127.013 152.149 1.00 49.18  ? 264 LEU A CB  1 
ATOM 490  C CG  . LEU A 1 174 ? 124.369 125.898 152.383 1.00 49.18  ? 264 LEU A CG  1 
ATOM 491  C CD1 . LEU A 1 174 ? 125.282 125.685 151.196 1.00 49.18  ? 264 LEU A CD1 1 
ATOM 492  C CD2 . LEU A 1 174 ? 125.144 126.163 153.649 1.00 49.18  ? 264 LEU A CD2 1 
ATOM 493  N N   . SER A 1 175 ? 120.657 128.513 152.961 1.00 46.81  ? 265 SER A N   1 
ATOM 494  C CA  . SER A 1 175 ? 119.951 129.533 153.723 1.00 46.81  ? 265 SER A CA  1 
ATOM 495  C C   . SER A 1 175 ? 119.159 128.906 154.860 1.00 46.81  ? 265 SER A C   1 
ATOM 496  O O   . SER A 1 175 ? 119.254 129.344 156.018 1.00 46.81  ? 265 SER A O   1 
ATOM 497  C CB  . SER A 1 175 ? 119.032 130.326 152.812 1.00 46.81  ? 265 SER A CB  1 
ATOM 498  O OG  . SER A 1 175 ? 118.243 131.212 153.577 1.00 46.81  ? 265 SER A OG  1 
ATOM 499  N N   . ARG A 1 176 ? 118.388 127.867 154.554 1.00 53.92  ? 266 ARG A N   1 
ATOM 500  C CA  . ARG A 1 176 ? 117.613 127.229 155.606 1.00 53.92  ? 266 ARG A CA  1 
ATOM 501  C C   . ARG A 1 176 ? 118.517 126.736 156.717 1.00 53.92  ? 266 ARG A C   1 
ATOM 502  O O   . ARG A 1 176 ? 118.365 127.133 157.878 1.00 53.92  ? 266 ARG A O   1 
ATOM 503  C CB  . ARG A 1 176 ? 116.807 126.061 155.058 1.00 53.92  ? 266 ARG A CB  1 
ATOM 504  C CG  . ARG A 1 176 ? 116.181 125.240 156.164 1.00 53.92  ? 266 ARG A CG  1 
ATOM 505  C CD  . ARG A 1 176 ? 115.862 123.849 155.696 1.00 53.92  ? 266 ARG A CD  1 
ATOM 506  N NE  . ARG A 1 176 ? 116.994 123.245 155.021 1.00 53.92  ? 266 ARG A NE  1 
ATOM 507  C CZ  . ARG A 1 176 ? 116.910 122.125 154.319 1.00 53.92  ? 266 ARG A CZ  1 
ATOM 508  N NH1 . ARG A 1 176 ? 115.745 121.510 154.206 1.00 53.92  ? 266 ARG A NH1 1 
ATOM 509  N NH2 . ARG A 1 176 ? 117.981 121.623 153.730 1.00 53.92  ? 266 ARG A NH2 1 
ATOM 510  N N   . ASN A 1 177 ? 119.476 125.878 156.371 1.00 55.69  ? 267 ASN A N   1 
ATOM 511  C CA  . ASN A 1 177 ? 120.261 125.216 157.402 1.00 55.69  ? 267 ASN A CA  1 
ATOM 512  C C   . ASN A 1 177 ? 120.986 126.230 158.268 1.00 55.69  ? 267 ASN A C   1 
ATOM 513  O O   . ASN A 1 177 ? 121.209 125.980 159.455 1.00 55.69  ? 267 ASN A O   1 
ATOM 514  C CB  . ASN A 1 177 ? 121.234 124.214 156.775 1.00 55.69  ? 267 ASN A CB  1 
ATOM 515  C CG  . ASN A 1 177 ? 121.569 123.059 157.716 1.00 55.69  ? 267 ASN A CG  1 
ATOM 516  O OD1 . ASN A 1 177 ? 121.595 123.217 158.929 1.00 55.69  ? 267 ASN A OD1 1 
ATOM 517  N ND2 . ASN A 1 177 ? 121.780 121.884 157.152 1.00 55.69  ? 267 ASN A ND2 1 
ATOM 518  N N   . ASN A 1 178 ? 121.316 127.398 157.719 1.00 55.54  ? 268 ASN A N   1 
ATOM 519  C CA  . ASN A 1 178 ? 121.964 128.399 158.556 1.00 55.54  ? 268 ASN A CA  1 
ATOM 520  C C   . ASN A 1 178 ? 120.969 129.056 159.499 1.00 55.54  ? 268 ASN A C   1 
ATOM 521  O O   . ASN A 1 178 ? 121.289 129.288 160.673 1.00 55.54  ? 268 ASN A O   1 
ATOM 522  C CB  . ASN A 1 178 ? 122.666 129.442 157.699 1.00 55.54  ? 268 ASN A CB  1 
ATOM 523  C CG  . ASN A 1 178 ? 124.156 129.233 157.650 1.00 55.54  ? 268 ASN A CG  1 
ATOM 524  O OD1 . ASN A 1 178 ? 124.920 129.963 158.277 1.00 55.54  ? 268 ASN A OD1 1 
ATOM 525  N ND2 . ASN A 1 178 ? 124.580 128.216 156.910 1.00 55.54  ? 268 ASN A ND2 1 
ATOM 526  N N   . ASN A 1 179 ? 119.762 129.374 159.019 1.00 63.11  ? 269 ASN A N   1 
ATOM 527  C CA  . ASN A 1 179 ? 118.749 129.802 159.978 1.00 63.11  ? 269 ASN A CA  1 
ATOM 528  C C   . ASN A 1 179 ? 118.595 128.778 161.078 1.00 63.11  ? 269 ASN A C   1 
ATOM 529  O O   . ASN A 1 179 ? 118.319 129.127 162.227 1.00 63.11  ? 269 ASN A O   1 
ATOM 530  C CB  . ASN A 1 179 ? 117.394 130.050 159.323 1.00 63.11  ? 269 ASN A CB  1 
ATOM 531  C CG  . ASN A 1 179 ? 117.208 131.490 158.885 1.00 63.11  ? 269 ASN A CG  1 
ATOM 532  O OD1 . ASN A 1 179 ? 117.665 132.407 159.552 1.00 63.11  ? 269 ASN A OD1 1 
ATOM 533  N ND2 . ASN A 1 179 ? 116.488 131.695 157.795 1.00 63.11  ? 269 ASN A ND2 1 
ATOM 534  N N   . MET A 1 180 ? 118.768 127.505 160.739 1.00 67.44  ? 270 MET A N   1 
ATOM 535  C CA  . MET A 1 180 ? 118.600 126.465 161.743 1.00 67.44  ? 270 MET A CA  1 
ATOM 536  C C   . MET A 1 180 ? 119.546 126.665 162.922 1.00 67.44  ? 270 MET A C   1 
ATOM 537  O O   . MET A 1 180 ? 119.087 126.826 164.058 1.00 67.44  ? 270 MET A O   1 
ATOM 538  C CB  . MET A 1 180 ? 118.796 125.090 161.119 1.00 67.44  ? 270 MET A CB  1 
ATOM 539  C CG  . MET A 1 180 ? 117.532 124.477 160.570 1.00 67.44  ? 270 MET A CG  1 
ATOM 540  S SD  . MET A 1 180 ? 117.836 122.834 159.899 1.00 67.44  ? 270 MET A SD  1 
ATOM 541  C CE  . MET A 1 180 ? 117.069 121.795 161.131 1.00 67.44  ? 270 MET A CE  1 
ATOM 542  N N   . ILE A 1 181 ? 120.858 126.669 162.682 1.00 62.78  ? 271 ILE A N   1 
ATOM 543  C CA  . ILE A 1 181 ? 121.788 126.917 163.777 1.00 62.78  ? 271 ILE A CA  1 
ATOM 544  C C   . ILE A 1 181 ? 121.469 128.239 164.441 1.00 62.78  ? 271 ILE A C   1 
ATOM 545  O O   . ILE A 1 181 ? 121.404 128.331 165.671 1.00 62.78  ? 271 ILE A O   1 
ATOM 546  C CB  . ILE A 1 181 ? 123.241 126.907 163.286 1.00 62.78  ? 271 ILE A CB  1 
ATOM 547  C CG1 . ILE A 1 181 ? 123.691 125.504 162.930 1.00 62.78  ? 271 ILE A CG1 1 
ATOM 548  C CG2 . ILE A 1 181 ? 124.138 127.434 164.363 1.00 62.78  ? 271 ILE A CG2 1 
ATOM 549  C CD1 . ILE A 1 181 ? 125.031 125.497 162.251 1.00 62.78  ? 271 ILE A CD1 1 
ATOM 550  N N   . MET A 1 182 ? 121.252 129.278 163.636 1.00 66.15  ? 272 MET A N   1 
ATOM 551  C CA  . MET A 1 182 ? 121.030 130.602 164.194 1.00 66.15  ? 272 MET A CA  1 
ATOM 552  C C   . MET A 1 182 ? 119.884 130.601 165.191 1.00 66.15  ? 272 MET A C   1 
ATOM 553  O O   . MET A 1 182 ? 119.891 131.373 166.156 1.00 66.15  ? 272 MET A O   1 
ATOM 554  C CB  . MET A 1 182 ? 120.769 131.597 163.072 1.00 66.15  ? 272 MET A CB  1 
ATOM 555  C CG  . MET A 1 182 ? 121.944 132.492 162.801 1.00 66.15  ? 272 MET A CG  1 
ATOM 556  S SD  . MET A 1 182 ? 122.210 133.499 164.261 1.00 66.15  ? 272 MET A SD  1 
ATOM 557  C CE  . MET A 1 182 ? 123.613 134.470 163.755 1.00 66.15  ? 272 MET A CE  1 
ATOM 558  N N   . ARG A 1 183 ? 118.896 129.735 164.982 1.00 78.90  ? 273 ARG A N   1 
ATOM 559  C CA  . ARG A 1 183 ? 117.757 129.697 165.886 1.00 78.90  ? 273 ARG A CA  1 
ATOM 560  C C   . ARG A 1 183 ? 118.141 129.269 167.293 1.00 78.90  ? 273 ARG A C   1 
ATOM 561  O O   . ARG A 1 183 ? 117.430 129.608 168.244 1.00 78.90  ? 273 ARG A O   1 
ATOM 562  C CB  . ARG A 1 183 ? 116.695 128.759 165.339 1.00 78.90  ? 273 ARG A CB  1 
ATOM 563  C CG  . ARG A 1 183 ? 115.412 128.768 166.123 1.00 78.90  ? 273 ARG A CG  1 
ATOM 564  C CD  . ARG A 1 183 ? 114.715 130.090 165.992 1.00 78.90  ? 273 ARG A CD  1 
ATOM 565  N NE  . ARG A 1 183 ? 113.778 130.298 167.081 1.00 78.90  ? 273 ARG A NE  1 
ATOM 566  C CZ  . ARG A 1 183 ? 114.142 130.652 168.303 1.00 78.90  ? 273 ARG A CZ  1 
ATOM 567  N NH1 . ARG A 1 183 ? 115.423 130.840 168.578 1.00 78.90  ? 273 ARG A NH1 1 
ATOM 568  N NH2 . ARG A 1 183 ? 113.229 130.823 169.246 1.00 78.90  ? 273 ARG A NH2 1 
ATOM 569  N N   . SER A 1 184 ? 119.254 128.551 167.452 1.00 81.12  ? 274 SER A N   1 
ATOM 570  C CA  . SER A 1 184 ? 119.613 128.032 168.766 1.00 81.12  ? 274 SER A CA  1 
ATOM 571  C C   . SER A 1 184 ? 120.013 129.133 169.734 1.00 81.12  ? 274 SER A C   1 
ATOM 572  O O   . SER A 1 184 ? 120.103 128.887 170.941 1.00 81.12  ? 274 SER A O   1 
ATOM 573  C CB  . SER A 1 184 ? 120.745 127.020 168.641 1.00 81.12  ? 274 SER A CB  1 
ATOM 574  O OG  . SER A 1 184 ? 120.326 125.747 169.094 1.00 81.12  ? 274 SER A OG  1 
ATOM 575  N N   . PHE A 1 185 ? 120.270 130.338 169.243 1.00 88.99  ? 275 PHE A N   1 
ATOM 576  C CA  . PHE A 1 185 ? 120.742 131.416 170.096 1.00 88.99  ? 275 PHE A CA  1 
ATOM 577  C C   . PHE A 1 185 ? 119.741 132.542 170.257 1.00 88.99  ? 275 PHE A C   1 
ATOM 578  O O   . PHE A 1 185 ? 120.151 133.676 170.516 1.00 88.99  ? 275 PHE A O   1 
ATOM 579  C CB  . PHE A 1 185 ? 122.053 131.971 169.550 1.00 88.99  ? 275 PHE A CB  1 
ATOM 580  C CG  . PHE A 1 185 ? 123.198 131.047 169.733 1.00 88.99  ? 275 PHE A CG  1 
ATOM 581  C CD1 . PHE A 1 185 ? 123.836 130.963 170.948 1.00 88.99  ? 275 PHE A CD1 1 
ATOM 582  C CD2 . PHE A 1 185 ? 123.618 130.238 168.702 1.00 88.99  ? 275 PHE A CD2 1 
ATOM 583  C CE1 . PHE A 1 185 ? 124.885 130.104 171.128 1.00 88.99  ? 275 PHE A CE1 1 
ATOM 584  C CE2 . PHE A 1 185 ? 124.668 129.377 168.876 1.00 88.99  ? 275 PHE A CE2 1 
ATOM 585  C CZ  . PHE A 1 185 ? 125.304 129.309 170.091 1.00 88.99  ? 275 PHE A CZ  1 
ATOM 586  N N   . ARG A 1 186 ? 118.446 132.263 170.127 1.00 91.28  ? 276 ARG A N   1 
ATOM 587  C CA  . ARG A 1 186 ? 117.413 133.293 170.207 1.00 91.28  ? 276 ARG A CA  1 
ATOM 588  C C   . ARG A 1 186 ? 117.676 134.431 169.229 1.00 91.28  ? 276 ARG A C   1 
ATOM 589  O O   . ARG A 1 186 ? 117.427 135.599 169.532 1.00 91.28  ? 276 ARG A O   1 
ATOM 590  C CB  . ARG A 1 186 ? 117.317 133.841 171.632 1.00 50.00  ? 276 ARG A CB  1 
ATOM 591  C CG  . ARG A 1 186 ? 116.812 132.833 172.651 1.00 50.00  ? 276 ARG A CG  1 
ATOM 592  C CD  . ARG A 1 186 ? 116.670 133.390 174.059 1.00 50.00  ? 276 ARG A CD  1 
ATOM 593  N NE  . ARG A 1 186 ? 116.249 132.368 175.013 1.00 50.00  ? 276 ARG A NE  1 
ATOM 594  C CZ  . ARG A 1 186 ? 116.163 132.561 176.321 1.00 50.00  ? 276 ARG A CZ  1 
ATOM 595  N NH1 . ARG A 1 186 ? 116.465 133.744 176.841 1.00 50.00  ? 276 ARG A NH1 1 
ATOM 596  N NH2 . ARG A 1 186 ? 115.771 131.573 177.115 1.00 50.00  ? 276 ARG A NH2 1 
ATOM 597  N N   . GLN A 1 187 ? 118.191 134.080 168.056 1.00 81.98  ? 277 GLN A N   1 
ATOM 598  C CA  . GLN A 1 187 ? 118.473 135.084 167.042 1.00 81.98  ? 277 GLN A CA  1 
ATOM 599  C C   . GLN A 1 187 ? 117.430 135.017 165.944 1.00 81.98  ? 277 GLN A C   1 
ATOM 600  O O   . GLN A 1 187 ? 116.993 133.931 165.563 1.00 81.98  ? 277 GLN A O   1 
ATOM 601  C CB  . GLN A 1 187 ? 119.857 134.858 166.445 1.00 81.98  ? 277 GLN A CB  1 
ATOM 602  C CG  . GLN A 1 187 ? 120.939 134.589 167.474 1.00 81.98  ? 277 GLN A CG  1 
ATOM 603  C CD  . GLN A 1 187 ? 121.156 135.753 168.419 1.00 81.98  ? 277 GLN A CD  1 
ATOM 604  O OE1 . GLN A 1 187 ? 120.707 136.872 168.166 1.00 81.98  ? 277 GLN A OE1 1 
ATOM 605  N NE2 . GLN A 1 187 ? 121.860 135.497 169.515 1.00 81.98  ? 277 GLN A NE2 1 
ATOM 606  N N   . PRO A 1 188 ? 117.028 136.182 165.423 1.00 79.09  ? 278 PRO A N   1 
ATOM 607  C CA  . PRO A 1 188 ? 116.001 136.201 164.385 1.00 79.09  ? 278 PRO A CA  1 
ATOM 608  C C   . PRO A 1 188 ? 116.491 135.515 163.122 1.00 79.09  ? 278 PRO A C   1 
ATOM 609  O O   . PRO A 1 188 ? 117.678 135.514 162.803 1.00 79.09  ? 278 PRO A O   1 
ATOM 610  C CB  . PRO A 1 188 ? 115.764 137.696 164.145 1.00 79.09  ? 278 PRO A CB  1 
ATOM 611  C CG  . PRO A 1 188 ? 116.381 138.385 165.323 1.00 79.09  ? 278 PRO A CG  1 
ATOM 612  C CD  . PRO A 1 188 ? 117.516 137.526 165.748 1.00 79.09  ? 278 PRO A CD  1 
ATOM 613  N N   . ILE A 1 189 ? 115.544 134.928 162.400 1.00 64.47  ? 279 ILE A N   1 
ATOM 614  C CA  . ILE A 1 189 ? 115.830 134.254 161.143 1.00 64.47  ? 279 ILE A CA  1 
ATOM 615  C C   . ILE A 1 189 ? 115.834 135.253 160.005 1.00 64.47  ? 279 ILE A C   1 
ATOM 616  O O   . ILE A 1 189 ? 115.411 136.401 160.169 1.00 64.47  ? 279 ILE A O   1 
ATOM 617  C CB  . ILE A 1 189 ? 114.806 133.152 160.868 1.00 64.47  ? 279 ILE A CB  1 
ATOM 618  C CG1 . ILE A 1 189 ? 113.423 133.695 161.193 1.00 64.47  ? 279 ILE A CG1 1 
ATOM 619  C CG2 . ILE A 1 189 ? 115.137 131.931 161.668 1.00 64.47  ? 279 ILE A CG2 1 
ATOM 620  C CD1 . ILE A 1 189 ? 112.321 132.709 161.016 1.00 64.47  ? 279 ILE A CD1 1 
ATOM 621  N N   . THR A 1 190 ? 116.305 134.823 158.845 1.00 55.68  ? 280 THR A N   1 
ATOM 622  C CA  . THR A 1 190 ? 116.343 135.660 157.661 1.00 55.68  ? 280 THR A CA  1 
ATOM 623  C C   . THR A 1 190 ? 115.412 135.096 156.600 1.00 55.68  ? 280 THR A C   1 
ATOM 624  O O   . THR A 1 190 ? 114.982 133.947 156.671 1.00 55.68  ? 280 THR A O   1 
ATOM 625  C CB  . THR A 1 190 ? 117.758 135.745 157.105 1.00 55.68  ? 280 THR A CB  1 
ATOM 626  O OG1 . THR A 1 190 ? 117.996 134.608 156.274 1.00 55.68  ? 280 THR A OG1 1 
ATOM 627  C CG2 . THR A 1 190 ? 118.757 135.735 158.237 1.00 55.68  ? 280 THR A CG2 1 
ATOM 628  N N   . GLU A 1 191 ? 115.119 135.918 155.602 1.00 50.80  ? 281 GLU A N   1 
ATOM 629  C CA  . GLU A 1 191 ? 114.235 135.525 154.510 1.00 50.80  ? 281 GLU A CA  1 
ATOM 630  C C   . GLU A 1 191 ? 114.890 134.387 153.741 1.00 50.80  ? 281 GLU A C   1 
ATOM 631  O O   . GLU A 1 191 ? 116.080 134.118 153.896 1.00 50.80  ? 281 GLU A O   1 
ATOM 632  C CB  . GLU A 1 191 ? 113.951 136.724 153.613 1.00 50.80  ? 281 GLU A CB  1 
ATOM 633  C CG  . GLU A 1 191 ? 112.785 136.554 152.643 1.00 50.80  ? 281 GLU A CG  1 
ATOM 634  C CD  . GLU A 1 191 ? 112.505 137.811 151.824 1.00 50.80  ? 281 GLU A CD  1 
ATOM 635  O OE1 . GLU A 1 191 ? 113.254 138.801 151.965 1.00 50.80  ? 281 GLU A OE1 1 
ATOM 636  O OE2 . GLU A 1 191 ? 111.532 137.810 151.041 1.00 50.80  ? 281 GLU A OE2 1 
ATOM 637  N N   . VAL A 1 192 ? 114.114 133.702 152.921 1.00 36.17  ? 282 VAL A N   1 
ATOM 638  C CA  . VAL A 1 192 ? 114.615 132.511 152.232 1.00 36.17  ? 282 VAL A CA  1 
ATOM 639  C C   . VAL A 1 192 ? 114.180 132.550 150.780 1.00 36.17  ? 282 VAL A C   1 
ATOM 640  O O   . VAL A 1 192 ? 113.029 132.908 150.499 1.00 36.17  ? 282 VAL A O   1 
ATOM 641  C CB  . VAL A 1 192 ? 114.094 131.267 152.925 1.00 36.17  ? 282 VAL A CB  1 
ATOM 642  C CG1 . VAL A 1 192 ? 113.962 130.142 151.948 1.00 36.17  ? 282 VAL A CG1 1 
ATOM 643  C CG2 . VAL A 1 192 ? 115.035 130.894 154.025 1.00 36.17  ? 282 VAL A CG2 1 
ATOM 644  N N   . PRO A 1 193 ? 115.023 132.175 149.832 1.00 42.83  ? 283 PRO A N   1 
ATOM 645  C CA  . PRO A 1 193 ? 114.630 132.272 148.430 1.00 42.83  ? 283 PRO A CA  1 
ATOM 646  C C   . PRO A 1 193 ? 113.661 131.165 148.077 1.00 42.83  ? 283 PRO A C   1 
ATOM 647  O O   . PRO A 1 193 ? 113.468 130.218 148.838 1.00 42.83  ? 283 PRO A O   1 
ATOM 648  C CB  . PRO A 1 193 ? 115.949 132.108 147.671 1.00 42.83  ? 283 PRO A CB  1 
ATOM 649  C CG  . PRO A 1 193 ? 117.008 132.030 148.719 1.00 42.83  ? 283 PRO A CG  1 
ATOM 650  C CD  . PRO A 1 193 ? 116.348 131.576 149.970 1.00 42.83  ? 283 PRO A CD  1 
ATOM 651  N N   . PHE A 1 194 ? 113.056 131.292 146.904 1.00 54.69  ? 284 PHE A N   1 
ATOM 652  C CA  . PHE A 1 194 ? 112.158 130.264 146.419 1.00 54.69  ? 284 PHE A CA  1 
ATOM 653  C C   . PHE A 1 194 ? 112.899 129.295 145.506 1.00 54.69  ? 284 PHE A C   1 
ATOM 654  O O   . PHE A 1 194 ? 113.937 129.607 144.923 1.00 54.69  ? 284 PHE A O   1 
ATOM 655  C CB  . PHE A 1 194 ? 110.981 130.885 145.679 1.00 54.69  ? 284 PHE A CB  1 
ATOM 656  C CG  . PHE A 1 194 ? 109.892 131.355 146.580 1.00 54.69  ? 284 PHE A CG  1 
ATOM 657  C CD1 . PHE A 1 194 ? 109.815 130.900 147.872 1.00 54.69  ? 284 PHE A CD1 1 
ATOM 658  C CD2 . PHE A 1 194 ? 108.943 132.243 146.133 1.00 54.69  ? 284 PHE A CD2 1 
ATOM 659  C CE1 . PHE A 1 194 ? 108.817 131.327 148.700 1.00 54.69  ? 284 PHE A CE1 1 
ATOM 660  C CE2 . PHE A 1 194 ? 107.941 132.665 146.957 1.00 54.69  ? 284 PHE A CE2 1 
ATOM 661  C CZ  . PHE A 1 194 ? 107.879 132.212 148.242 1.00 54.69  ? 284 PHE A CZ  1 
ATOM 662  N N   . PHE A 1 195 ? 112.311 128.115 145.356 1.00 55.45  ? 285 PHE A N   1 
ATOM 663  C CA  . PHE A 1 195 ? 112.879 127.018 144.590 1.00 55.45  ? 285 PHE A CA  1 
ATOM 664  C C   . PHE A 1 195 ? 113.288 127.442 143.183 1.00 55.45  ? 285 PHE A C   1 
ATOM 665  O O   . PHE A 1 195 ? 114.052 126.742 142.520 1.00 55.45  ? 285 PHE A O   1 
ATOM 666  C CB  . PHE A 1 195 ? 111.864 125.880 144.559 1.00 55.45  ? 285 PHE A CB  1 
ATOM 667  C CG  . PHE A 1 195 ? 112.010 124.964 143.398 1.00 55.45  ? 285 PHE A CG  1 
ATOM 668  C CD1 . PHE A 1 195 ? 111.130 125.035 142.337 1.00 55.45  ? 285 PHE A CD1 1 
ATOM 669  C CD2 . PHE A 1 195 ? 113.005 124.014 143.371 1.00 55.45  ? 285 PHE A CD2 1 
ATOM 670  C CE1 . PHE A 1 195 ? 111.251 124.188 141.260 1.00 55.45  ? 285 PHE A CE1 1 
ATOM 671  C CE2 . PHE A 1 195 ? 113.128 123.162 142.297 1.00 55.45  ? 285 PHE A CE2 1 
ATOM 672  C CZ  . PHE A 1 195 ? 112.250 123.250 141.240 1.00 55.45  ? 285 PHE A CZ  1 
ATOM 673  N N   . ASN A 1 196 ? 112.814 128.595 142.723 1.00 51.59  ? 286 ASN A N   1 
ATOM 674  C CA  . ASN A 1 196 ? 113.179 129.111 141.413 1.00 51.59  ? 286 ASN A CA  1 
ATOM 675  C C   . ASN A 1 196 ? 114.076 130.335 141.492 1.00 51.59  ? 286 ASN A C   1 
ATOM 676  O O   . ASN A 1 196 ? 114.509 130.836 140.453 1.00 51.59  ? 286 ASN A O   1 
ATOM 677  C CB  . ASN A 1 196 ? 111.926 129.450 140.618 1.00 51.59  ? 286 ASN A CB  1 
ATOM 678  C CG  . ASN A 1 196 ? 111.221 130.659 141.168 1.00 51.59  ? 286 ASN A CG  1 
ATOM 679  O OD1 . ASN A 1 196 ? 111.216 130.883 142.374 1.00 51.59  ? 286 ASN A OD1 1 
ATOM 680  N ND2 . ASN A 1 196 ? 110.608 131.443 140.293 1.00 51.59  ? 286 ASN A ND2 1 
ATOM 681  N N   . GLY A 1 197 ? 114.353 130.839 142.693 1.00 55.48  ? 287 GLY A N   1 
ATOM 682  C CA  . GLY A 1 197 ? 115.342 131.883 142.879 1.00 55.48  ? 287 GLY A CA  1 
ATOM 683  C C   . GLY A 1 197 ? 114.832 133.240 143.321 1.00 55.48  ? 287 GLY A C   1 
ATOM 684  O O   . GLY A 1 197 ? 115.490 133.885 144.149 1.00 55.48  ? 287 GLY A O   1 
ATOM 685  N N   . ASP A 1 198 ? 113.694 133.696 142.810 1.00 66.52  ? 288 ASP A N   1 
ATOM 686  C CA  . ASP A 1 198 ? 113.169 135.017 143.122 1.00 66.52  ? 288 ASP A CA  1 
ATOM 687  C C   . ASP A 1 198 ? 112.980 135.177 144.620 1.00 66.52  ? 288 ASP A C   1 
ATOM 688  O O   . ASP A 1 198 ? 112.955 134.207 145.376 1.00 66.52  ? 288 ASP A O   1 
ATOM 689  C CB  . ASP A 1 198 ? 111.829 135.247 142.433 1.00 66.52  ? 288 ASP A CB  1 
ATOM 690  C CG  . ASP A 1 198 ? 111.846 134.834 140.988 1.00 66.52  ? 288 ASP A CG  1 
ATOM 691  O OD1 . ASP A 1 198 ? 112.860 135.093 140.315 1.00 66.52  ? 288 ASP A OD1 1 
ATOM 692  O OD2 . ASP A 1 198 ? 110.842 134.252 140.525 1.00 66.52  ? 288 ASP A OD2 1 
ATOM 693  N N   . ILE A 1 199 ? 112.855 136.423 145.048 1.00 65.00  ? 289 ILE A N   1 
ATOM 694  C CA  . ILE A 1 199 ? 112.396 136.687 146.405 1.00 65.00  ? 289 ILE A CA  1 
ATOM 695  C C   . ILE A 1 199 ? 110.891 136.480 146.379 1.00 65.00  ? 289 ILE A C   1 
ATOM 696  O O   . ILE A 1 199 ? 110.270 136.638 145.319 1.00 65.00  ? 289 ILE A O   1 
ATOM 697  C CB  . ILE A 1 199 ? 112.816 138.088 146.876 1.00 65.00  ? 289 ILE A CB  1 
ATOM 698  C CG1 . ILE A 1 199 ? 113.833 137.970 148.018 1.00 65.00  ? 289 ILE A CG1 1 
ATOM 699  C CG2 . ILE A 1 199 ? 111.620 138.905 147.312 1.00 65.00  ? 289 ILE A CG2 1 
ATOM 700  C CD1 . ILE A 1 199 ? 115.204 138.543 147.689 1.00 65.00  ? 289 ILE A CD1 1 
ATOM 701  N N   . PRO A 1 200 ? 110.273 136.081 147.488 1.00 74.19  ? 290 PRO A N   1 
ATOM 702  C CA  . PRO A 1 200 ? 108.834 135.817 147.486 1.00 74.19  ? 290 PRO A CA  1 
ATOM 703  C C   . PRO A 1 200 ? 108.031 137.027 147.040 1.00 74.19  ? 290 PRO A C   1 
ATOM 704  O O   . PRO A 1 200 ? 108.569 138.120 146.853 1.00 74.19  ? 290 PRO A O   1 
ATOM 705  C CB  . PRO A 1 200 ? 108.541 135.471 148.948 1.00 74.19  ? 290 PRO A CB  1 
ATOM 706  C CG  . PRO A 1 200 ? 109.815 134.999 149.479 1.00 74.19  ? 290 PRO A CG  1 
ATOM 707  C CD  . PRO A 1 200 ? 110.884 135.776 148.787 1.00 74.19  ? 290 PRO A CD  1 
ATOM 708  N N   . ASP A 1 201 ? 106.730 136.825 146.861 1.00 96.89  ? 291 ASP A N   1 
ATOM 709  C CA  . ASP A 1 201 ? 105.867 137.939 146.518 1.00 96.89  ? 291 ASP A CA  1 
ATOM 710  C C   . ASP A 1 201 ? 105.959 139.006 147.613 1.00 96.89  ? 291 ASP A C   1 
ATOM 711  O O   . ASP A 1 201 ? 105.564 138.740 148.755 1.00 96.89  ? 291 ASP A O   1 
ATOM 712  C CB  . ASP A 1 201 ? 104.423 137.498 146.344 1.00 96.89  ? 291 ASP A CB  1 
ATOM 713  C CG  . ASP A 1 201 ? 103.538 138.624 145.856 1.00 96.89  ? 291 ASP A CG  1 
ATOM 714  O OD1 . ASP A 1 201 ? 103.118 138.582 144.682 1.00 96.89  ? 291 ASP A OD1 1 
ATOM 715  O OD2 . ASP A 1 201 ? 103.288 139.563 146.636 1.00 96.89  ? 291 ASP A OD2 1 
ATOM 716  N N   . PRO A 1 202 ? 106.457 140.197 147.299 1.00 104.00 ? 292 PRO A N   1 
ATOM 717  C CA  . PRO A 1 202 ? 106.727 141.178 148.362 1.00 104.00 ? 292 PRO A CA  1 
ATOM 718  C C   . PRO A 1 202 ? 105.493 141.609 149.121 1.00 104.00 ? 292 PRO A C   1 
ATOM 719  O O   . PRO A 1 202 ? 105.625 142.248 150.171 1.00 104.00 ? 292 PRO A O   1 
ATOM 720  C CB  . PRO A 1 202 ? 107.357 142.352 147.602 1.00 104.00 ? 292 PRO A CB  1 
ATOM 721  C CG  . PRO A 1 202 ? 107.826 141.762 146.302 1.00 104.00 ? 292 PRO A CG  1 
ATOM 722  C CD  . PRO A 1 202 ? 106.836 140.699 145.973 1.00 104.00 ? 292 PRO A CD  1 
ATOM 723  N N   . ASN A 1 203 ? 104.299 141.288 148.632 1.00 108.36 ? 293 ASN A N   1 
ATOM 724  C CA  . ASN A 1 203 ? 103.106 141.406 149.452 1.00 108.36 ? 293 ASN A CA  1 
ATOM 725  C C   . ASN A 1 203 ? 103.011 140.298 150.488 1.00 108.36 ? 293 ASN A C   1 
ATOM 726  O O   . ASN A 1 203 ? 102.246 140.428 151.449 1.00 108.36 ? 293 ASN A O   1 
ATOM 727  C CB  . ASN A 1 203 ? 101.852 141.381 148.578 1.00 108.36 ? 293 ASN A CB  1 
ATOM 728  C CG  . ASN A 1 203 ? 100.583 141.535 149.381 1.00 108.36 ? 293 ASN A CG  1 
ATOM 729  O OD1 . ASN A 1 203 ? 100.557 142.233 150.393 1.00 108.36 ? 293 ASN A OD1 1 
ATOM 730  N ND2 . ASN A 1 203 ? 99.530  140.848 148.957 1.00 108.36 ? 293 ASN A ND2 1 
ATOM 731  N N   . LEU A 1 204 ? 103.779 139.228 150.334 1.00 97.25  ? 294 LEU A N   1 
ATOM 732  C CA  . LEU A 1 204 ? 103.668 138.130 151.270 1.00 97.25  ? 294 LEU A CA  1 
ATOM 733  C C   . LEU A 1 204 ? 104.576 138.388 152.468 1.00 97.25  ? 294 LEU A C   1 
ATOM 734  O O   . LEU A 1 204 ? 105.774 138.634 152.313 1.00 97.25  ? 294 LEU A O   1 
ATOM 735  C CB  . LEU A 1 204 ? 104.023 136.812 150.604 1.00 97.25  ? 294 LEU A CB  1 
ATOM 736  C CG  . LEU A 1 204 ? 102.915 136.153 149.772 1.00 97.25  ? 294 LEU A CG  1 
ATOM 737  C CD1 . LEU A 1 204 ? 102.197 135.107 150.602 1.00 97.25  ? 294 LEU A CD1 1 
ATOM 738  C CD2 . LEU A 1 204 ? 101.910 137.143 149.193 1.00 97.25  ? 294 LEU A CD2 1 
ATOM 739  N N   . PRO A 1 205 ? 104.027 138.333 153.658 1.00 95.77  ? 295 PRO A N   1 
ATOM 740  C CA  . PRO A 1 205 ? 104.733 138.862 154.830 1.00 95.77  ? 295 PRO A CA  1 
ATOM 741  C C   . PRO A 1 205 ? 106.026 138.128 155.105 1.00 95.77  ? 295 PRO A C   1 
ATOM 742  O O   . PRO A 1 205 ? 106.053 136.897 155.099 1.00 95.77  ? 295 PRO A O   1 
ATOM 743  C CB  . PRO A 1 205 ? 103.727 138.661 155.969 1.00 95.77  ? 295 PRO A CB  1 
ATOM 744  C CG  . PRO A 1 205 ? 102.428 138.311 155.302 1.00 95.77  ? 295 PRO A CG  1 
ATOM 745  C CD  . PRO A 1 205 ? 102.776 137.659 154.017 1.00 95.77  ? 295 PRO A CD  1 
ATOM 746  N N   . ARG A 1 206 ? 107.102 138.868 155.330 1.00 94.93  ? 296 ARG A N   1 
ATOM 747  C CA  . ARG A 1 206 ? 108.374 138.251 155.678 1.00 94.93  ? 296 ARG A CA  1 
ATOM 748  C C   . ARG A 1 206 ? 108.257 137.552 157.028 1.00 94.93  ? 296 ARG A C   1 
ATOM 749  O O   . ARG A 1 206 ? 107.422 137.920 157.858 1.00 94.93  ? 296 ARG A O   1 
ATOM 750  C CB  . ARG A 1 206 ? 109.479 139.298 155.686 1.00 94.93  ? 296 ARG A CB  1 
ATOM 751  C CG  . ARG A 1 206 ? 109.941 139.682 154.297 1.00 94.93  ? 296 ARG A CG  1 
ATOM 752  C CD  . ARG A 1 206 ? 110.470 141.097 154.254 1.00 94.93  ? 296 ARG A CD  1 
ATOM 753  N NE  . ARG A 1 206 ? 111.265 141.326 153.054 1.00 94.93  ? 296 ARG A NE  1 
ATOM 754  C CZ  . ARG A 1 206 ? 112.530 141.730 153.067 1.00 94.93  ? 296 ARG A CZ  1 
ATOM 755  N NH1 . ARG A 1 206 ? 113.136 141.965 154.221 1.00 94.93  ? 296 ARG A NH1 1 
ATOM 756  N NH2 . ARG A 1 206 ? 113.185 141.907 151.930 1.00 94.93  ? 296 ARG A NH2 1 
ATOM 757  N N   . ILE A 1 207 ? 109.092 136.538 157.241 1.00 87.57  ? 297 ILE A N   1 
ATOM 758  C CA  . ILE A 1 207 ? 108.934 135.608 158.353 1.00 87.57  ? 297 ILE A CA  1 
ATOM 759  C C   . ILE A 1 207 ? 110.067 135.848 159.342 1.00 87.57  ? 297 ILE A C   1 
ATOM 760  O O   . ILE A 1 207 ? 111.229 135.955 158.947 1.00 87.57  ? 297 ILE A O   1 
ATOM 761  C CB  . ILE A 1 207 ? 108.936 134.165 157.855 1.00 87.57  ? 297 ILE A CB  1 
ATOM 762  C CG1 . ILE A 1 207 ? 108.125 134.082 156.571 1.00 87.57  ? 297 ILE A CG1 1 
ATOM 763  C CG2 . ILE A 1 207 ? 108.347 133.260 158.896 1.00 87.57  ? 297 ILE A CG2 1 
ATOM 764  C CD1 . ILE A 1 207 ? 108.486 132.911 155.715 1.00 87.57  ? 297 ILE A CD1 1 
ATOM 765  N N   . THR A 1 208 ? 109.743 135.919 160.633 1.00 87.74  ? 298 THR A N   1 
ATOM 766  C CA  . THR A 1 208 ? 110.750 136.196 161.648 1.00 87.74  ? 298 THR A CA  1 
ATOM 767  C C   . THR A 1 208 ? 110.739 135.219 162.803 1.00 87.74  ? 298 THR A C   1 
ATOM 768  O O   . THR A 1 208 ? 111.786 135.005 163.418 1.00 87.74  ? 298 THR A O   1 
ATOM 769  C CB  . THR A 1 208 ? 110.558 137.597 162.236 1.00 87.74  ? 298 THR A CB  1 
ATOM 770  O OG1 . THR A 1 208 ? 109.308 137.643 162.934 1.00 87.74  ? 298 THR A OG1 1 
ATOM 771  C CG2 . THR A 1 208 ? 110.558 138.641 161.140 1.00 87.74  ? 298 THR A CG2 1 
ATOM 772  N N   . ARG A 1 209 ? 109.585 134.660 163.140 1.00 100.17 ? 299 ARG A N   1 
ATOM 773  C CA  . ARG A 1 209 ? 109.484 133.721 164.237 1.00 100.17 ? 299 ARG A CA  1 
ATOM 774  C C   . ARG A 1 209 ? 108.193 132.940 164.091 1.00 100.17 ? 299 ARG A C   1 
ATOM 775  O O   . ARG A 1 209 ? 107.448 133.096 163.121 1.00 100.17 ? 299 ARG A O   1 
ATOM 776  C CB  . ARG A 1 209 ? 109.573 134.438 165.583 1.00 100.17 ? 299 ARG A CB  1 
ATOM 777  C CG  . ARG A 1 209 ? 108.907 135.789 165.605 1.00 100.17 ? 299 ARG A CG  1 
ATOM 778  C CD  . ARG A 1 209 ? 109.308 136.518 166.864 1.00 100.17 ? 299 ARG A CD  1 
ATOM 779  N NE  . ARG A 1 209 ? 110.749 136.438 167.084 1.00 100.17 ? 299 ARG A NE  1 
ATOM 780  C CZ  . ARG A 1 209 ? 111.348 136.759 168.226 1.00 100.17 ? 299 ARG A CZ  1 
ATOM 781  N NH1 . ARG A 1 209 ? 110.629 137.184 169.256 1.00 100.17 ? 299 ARG A NH1 1 
ATOM 782  N NH2 . ARG A 1 209 ? 112.664 136.656 168.340 1.00 100.17 ? 299 ARG A NH2 1 
ATOM 783  N N   . ILE A 1 210 ? 107.919 132.105 165.084 1.00 105.91 ? 300 ILE A N   1 
ATOM 784  C CA  . ILE A 1 210 ? 106.937 131.057 164.875 1.00 105.91 ? 300 ILE A CA  1 
ATOM 785  C C   . ILE A 1 210 ? 105.519 131.608 164.890 1.00 105.91 ? 300 ILE A C   1 
ATOM 786  O O   . ILE A 1 210 ? 104.709 131.264 164.020 1.00 105.91 ? 300 ILE A O   1 
ATOM 787  C CB  . ILE A 1 210 ? 107.147 129.955 165.921 1.00 105.91 ? 300 ILE A CB  1 
ATOM 788  C CG1 . ILE A 1 210 ? 106.074 128.883 165.787 1.00 105.91 ? 300 ILE A CG1 1 
ATOM 789  C CG2 . ILE A 1 210 ? 107.177 130.539 167.320 1.00 105.91 ? 300 ILE A CG2 1 
ATOM 790  C CD1 . ILE A 1 210 ? 106.489 127.569 166.371 1.00 105.91 ? 300 ILE A CD1 1 
ATOM 791  N N   . GLU A 1 211 ? 105.195 132.474 165.848 1.00 109.49 ? 301 GLU A N   1 
ATOM 792  C CA  . GLU A 1 211 ? 103.841 133.009 165.925 1.00 109.49 ? 301 GLU A CA  1 
ATOM 793  C C   . GLU A 1 211 ? 103.472 133.749 164.649 1.00 109.49 ? 301 GLU A C   1 
ATOM 794  O O   . GLU A 1 211 ? 102.295 133.787 164.261 1.00 109.49 ? 301 GLU A O   1 
ATOM 795  C CB  . GLU A 1 211 ? 103.722 133.925 167.140 1.00 109.49 ? 301 GLU A CB  1 
ATOM 796  C CG  . GLU A 1 211 ? 104.487 135.229 167.016 1.00 109.49 ? 301 GLU A CG  1 
ATOM 797  C CD  . GLU A 1 211 ? 105.954 135.080 167.357 1.00 109.49 ? 301 GLU A CD  1 
ATOM 798  O OE1 . GLU A 1 211 ? 106.567 134.056 166.981 1.00 109.49 ? 301 GLU A OE1 1 
ATOM 799  O OE2 . GLU A 1 211 ? 106.487 135.983 168.032 1.00 109.49 ? 301 GLU A OE2 1 
ATOM 800  N N   . ASP A 1 212 ? 104.464 134.344 163.985 1.00 114.86 ? 302 ASP A N   1 
ATOM 801  C CA  . ASP A 1 212 ? 104.228 134.935 162.674 1.00 114.86 ? 302 ASP A CA  1 
ATOM 802  C C   . ASP A 1 212 ? 103.547 133.941 161.753 1.00 114.86 ? 302 ASP A C   1 
ATOM 803  O O   . ASP A 1 212 ? 102.524 134.253 161.133 1.00 114.86 ? 302 ASP A O   1 
ATOM 804  C CB  . ASP A 1 212 ? 105.546 135.411 162.069 1.00 114.86 ? 302 ASP A CB  1 
ATOM 805  C CG  . ASP A 1 212 ? 105.379 135.940 160.659 1.00 114.86 ? 302 ASP A CG  1 
ATOM 806  O OD1 . ASP A 1 212 ? 104.625 136.921 160.471 1.00 114.86 ? 302 ASP A OD1 1 
ATOM 807  O OD2 . ASP A 1 212 ? 106.008 135.375 159.739 1.00 114.86 ? 302 ASP A OD2 1 
ATOM 808  N N   . ILE A 1 213 ? 104.100 132.738 161.655 1.00 103.77 ? 303 ILE A N   1 
ATOM 809  C CA  . ILE A 1 213 ? 103.427 131.691 160.908 1.00 103.77 ? 303 ILE A CA  1 
ATOM 810  C C   . ILE A 1 213 ? 102.075 131.394 161.525 1.00 103.77 ? 303 ILE A C   1 
ATOM 811  O O   . ILE A 1 213 ? 101.048 131.397 160.836 1.00 103.77 ? 303 ILE A O   1 
ATOM 812  C CB  . ILE A 1 213 ? 104.303 130.433 160.857 1.00 103.77 ? 303 ILE A CB  1 
ATOM 813  C CG1 . ILE A 1 213 ? 105.629 130.750 160.182 1.00 103.77 ? 303 ILE A CG1 1 
ATOM 814  C CG2 . ILE A 1 213 ? 103.583 129.341 160.117 1.00 103.77 ? 303 ILE A CG2 1 
ATOM 815  C CD1 . ILE A 1 213 ? 106.283 129.545 159.566 1.00 103.77 ? 303 ILE A CD1 1 
ATOM 816  N N   . ASP A 1 214 ? 102.043 131.160 162.838 1.00 114.18 ? 304 ASP A N   1 
ATOM 817  C CA  . ASP A 1 214 ? 100.822 130.683 163.479 1.00 114.18 ? 304 ASP A CA  1 
ATOM 818  C C   . ASP A 1 214 ? 99.660  131.645 163.304 1.00 114.18 ? 304 ASP A C   1 
ATOM 819  O O   . ASP A 1 214 ? 98.522  131.286 163.620 1.00 114.18 ? 304 ASP A O   1 
ATOM 820  C CB  . ASP A 1 214 ? 101.055 130.434 164.968 1.00 114.18 ? 304 ASP A CB  1 
ATOM 821  C CG  . ASP A 1 214 ? 100.162 129.333 165.518 1.00 114.18 ? 304 ASP A CG  1 
ATOM 822  O OD1 . ASP A 1 214 ? 99.549  128.600 164.717 1.00 114.18 ? 304 ASP A OD1 1 
ATOM 823  O OD2 . ASP A 1 214 ? 100.059 129.201 166.753 1.00 114.18 ? 304 ASP A OD2 1 
ATOM 824  N N   . SER A 1 215 ? 99.920  132.855 162.819 1.00 120.15 ? 305 SER A N   1 
ATOM 825  C CA  . SER A 1 215 ? 98.860  133.816 162.566 1.00 120.15 ? 305 SER A CA  1 
ATOM 826  C C   . SER A 1 215 ? 98.498  133.933 161.094 1.00 120.15 ? 305 SER A C   1 
ATOM 827  O O   . SER A 1 215 ? 97.621  134.731 160.750 1.00 120.15 ? 305 SER A O   1 
ATOM 828  C CB  . SER A 1 215 ? 99.271  135.189 163.096 1.00 120.15 ? 305 SER A CB  1 
ATOM 829  O OG  . SER A 1 215 ? 99.416  136.120 162.041 1.00 120.15 ? 305 SER A OG  1 
ATOM 830  N N   . LEU A 1 216 ? 99.137  133.165 160.223 1.00 114.21 ? 306 LEU A N   1 
ATOM 831  C CA  . LEU A 1 216 ? 98.994  133.394 158.795 1.00 114.21 ? 306 LEU A CA  1 
ATOM 832  C C   . LEU A 1 216 ? 97.671  132.836 158.277 1.00 114.21 ? 306 LEU A C   1 
ATOM 833  O O   . LEU A 1 216 ? 97.047  131.984 158.913 1.00 114.21 ? 306 LEU A O   1 
ATOM 834  C CB  . LEU A 1 216 ? 100.163 132.758 158.051 1.00 114.21 ? 306 LEU A CB  1 
ATOM 835  C CG  . LEU A 1 216 ? 100.285 133.108 156.573 1.00 114.21 ? 306 LEU A CG  1 
ATOM 836  C CD1 . LEU A 1 216 ? 100.111 134.606 156.388 1.00 114.21 ? 306 LEU A CD1 1 
ATOM 837  C CD2 . LEU A 1 216 ? 101.612 132.646 156.014 1.00 114.21 ? 306 LEU A CD2 1 
ATOM 838  N N   . SER A 1 217 ? 97.244  133.335 157.119 1.00 116.35 ? 307 SER A N   1 
ATOM 839  C CA  . SER A 1 217 ? 96.052  132.829 156.455 1.00 116.35 ? 307 SER A CA  1 
ATOM 840  C C   . SER A 1 217 ? 96.360  131.538 155.707 1.00 116.35 ? 307 SER A C   1 
ATOM 841  O O   . SER A 1 217 ? 97.505  131.250 155.348 1.00 116.35 ? 307 SER A O   1 
ATOM 842  C CB  . SER A 1 217 ? 95.501  133.860 155.475 1.00 116.35 ? 307 SER A CB  1 
ATOM 843  O OG  . SER A 1 217 ? 95.649  133.403 154.144 1.00 116.35 ? 307 SER A OG  1 
ATOM 844  N N   . GLU A 1 218 ? 95.304  130.762 155.455 1.00 109.09 ? 308 GLU A N   1 
ATOM 845  C CA  . GLU A 1 218 ? 95.481  129.444 154.859 1.00 109.09 ? 308 GLU A CA  1 
ATOM 846  C C   . GLU A 1 218 ? 96.002  129.552 153.431 1.00 109.09 ? 308 GLU A C   1 
ATOM 847  O O   . GLU A 1 218 ? 96.943  128.845 153.053 1.00 109.09 ? 308 GLU A O   1 
ATOM 848  C CB  . GLU A 1 218 ? 94.160  128.662 154.961 1.00 109.09 ? 308 GLU A CB  1 
ATOM 849  C CG  . GLU A 1 218 ? 93.839  127.504 153.980 1.00 109.09 ? 308 GLU A CG  1 
ATOM 850  C CD  . GLU A 1 218 ? 93.915  127.859 152.505 1.00 109.09 ? 308 GLU A CD  1 
ATOM 851  O OE1 . GLU A 1 218 ? 93.326  128.883 152.118 1.00 109.09 ? 308 GLU A OE1 1 
ATOM 852  O OE2 . GLU A 1 218 ? 94.572  127.122 151.751 1.00 109.09 ? 308 GLU A OE2 1 
ATOM 853  N N   . GLU A 1 219 ? 95.394  130.413 152.618 1.00 113.84 ? 309 GLU A N   1 
ATOM 854  C CA  . GLU A 1 219 ? 95.851  130.537 151.241 1.00 113.84 ? 309 GLU A CA  1 
ATOM 855  C C   . GLU A 1 219 ? 97.312  130.942 151.197 1.00 113.84 ? 309 GLU A C   1 
ATOM 856  O O   . GLU A 1 219 ? 98.074  130.468 150.349 1.00 113.84 ? 309 GLU A O   1 
ATOM 857  C CB  . GLU A 1 219 ? 94.981  131.534 150.482 1.00 113.84 ? 309 GLU A CB  1 
ATOM 858  C CG  . GLU A 1 219 ? 94.715  132.814 151.237 1.00 113.84 ? 309 GLU A CG  1 
ATOM 859  C CD  . GLU A 1 219 ? 95.838  133.815 151.103 1.00 113.84 ? 309 GLU A CD  1 
ATOM 860  O OE1 . GLU A 1 219 ? 96.660  133.668 150.176 1.00 113.84 ? 309 GLU A OE1 1 
ATOM 861  O OE2 . GLU A 1 219 ? 95.911  134.734 151.940 1.00 113.84 ? 309 GLU A OE2 1 
ATOM 862  N N   . ASN A 1 220 ? 97.725  131.809 152.116 1.00 109.26 ? 310 ASN A N   1 
ATOM 863  C CA  . ASN A 1 220 ? 99.127  132.187 152.175 1.00 109.26 ? 310 ASN A CA  1 
ATOM 864  C C   . ASN A 1 220 ? 99.988  130.999 152.558 1.00 109.26 ? 310 ASN A C   1 
ATOM 865  O O   . ASN A 1 220 ? 101.110 130.849 152.061 1.00 109.26 ? 310 ASN A O   1 
ATOM 866  C CB  . ASN A 1 220 ? 99.316  133.326 153.164 1.00 109.26 ? 310 ASN A CB  1 
ATOM 867  C CG  . ASN A 1 220 ? 98.861  134.645 152.609 1.00 109.26 ? 310 ASN A CG  1 
ATOM 868  O OD1 . ASN A 1 220 ? 99.010  134.912 151.418 1.00 109.26 ? 310 ASN A OD1 1 
ATOM 869  N ND2 . ASN A 1 220 ? 98.306  135.488 153.467 1.00 109.26 ? 310 ASN A ND2 1 
ATOM 870  N N   . CYS A 1 221 ? 99.490  130.157 153.459 1.00 102.98 ? 311 CYS A N   1 
ATOM 871  C CA  . CYS A 1 221 ? 100.212 128.940 153.793 1.00 102.98 ? 311 CYS A CA  1 
ATOM 872  C C   . CYS A 1 221 ? 100.443 128.100 152.550 1.00 102.98 ? 311 CYS A C   1 
ATOM 873  O O   . CYS A 1 221 ? 101.553 127.614 152.310 1.00 102.98 ? 311 CYS A O   1 
ATOM 874  C CB  . CYS A 1 221 ? 99.440  128.146 154.841 1.00 102.98 ? 311 CYS A CB  1 
ATOM 875  S SG  . CYS A 1 221 ? 99.962  126.426 154.991 1.00 102.98 ? 311 CYS A SG  1 
ATOM 876  N N   . THR A 1 222 ? 99.397  127.907 151.755 1.00 93.44  ? 312 THR A N   1 
ATOM 877  C CA  . THR A 1 222 ? 99.564  127.150 150.525 1.00 93.44  ? 312 THR A CA  1 
ATOM 878  C C   . THR A 1 222 ? 100.560 127.818 149.600 1.00 93.44  ? 312 THR A C   1 
ATOM 879  O O   . THR A 1 222 ? 101.417 127.143 149.020 1.00 93.44  ? 312 THR A O   1 
ATOM 880  C CB  . THR A 1 222 ? 98.225  126.987 149.824 1.00 93.44  ? 312 THR A CB  1 
ATOM 881  O OG1 . THR A 1 222 ? 97.628  128.277 149.652 1.00 93.44  ? 312 THR A OG1 1 
ATOM 882  C CG2 . THR A 1 222 ? 97.310  126.104 150.644 1.00 93.44  ? 312 THR A CG2 1 
ATOM 883  N N   . ARG A 1 223 ? 100.443 129.131 149.432 1.00 88.47  ? 313 ARG A N   1 
ATOM 884  C CA  . ARG A 1 223 ? 101.410 129.853 148.621 1.00 88.47  ? 313 ARG A CA  1 
ATOM 885  C C   . ARG A 1 223 ? 102.820 129.506 149.053 1.00 88.47  ? 313 ARG A C   1 
ATOM 886  O O   . ARG A 1 223 ? 103.621 129.007 148.259 1.00 88.47  ? 313 ARG A O   1 
ATOM 887  C CB  . ARG A 1 223 ? 101.170 131.357 148.730 1.00 88.47  ? 313 ARG A CB  1 
ATOM 888  C CG  . ARG A 1 223 ? 99.850  131.814 148.159 1.00 88.47  ? 313 ARG A CG  1 
ATOM 889  C CD  . ARG A 1 223 ? 99.773  133.321 148.110 1.00 88.47  ? 313 ARG A CD  1 
ATOM 890  N NE  . ARG A 1 223 ? 100.881 133.874 147.345 1.00 88.47  ? 313 ARG A NE  1 
ATOM 891  C CZ  . ARG A 1 223 ? 100.865 135.073 146.780 1.00 88.47  ? 313 ARG A CZ  1 
ATOM 892  N NH1 . ARG A 1 223 ? 99.794  135.843 146.891 1.00 88.47  ? 313 ARG A NH1 1 
ATOM 893  N NH2 . ARG A 1 223 ? 101.917 135.499 146.103 1.00 88.47  ? 313 ARG A NH2 1 
ATOM 894  N N   . TYR A 1 224 ? 103.125 129.740 150.324 1.00 77.95  ? 314 TYR A N   1 
ATOM 895  C CA  . TYR A 1 224 ? 104.432 129.380 150.849 1.00 77.95  ? 314 TYR A CA  1 
ATOM 896  C C   . TYR A 1 224 ? 104.796 127.956 150.484 1.00 77.95  ? 314 TYR A C   1 
ATOM 897  O O   . TYR A 1 224 ? 105.794 127.722 149.796 1.00 77.95  ? 314 TYR A O   1 
ATOM 898  C CB  . TYR A 1 224 ? 104.461 129.575 152.359 1.00 77.95  ? 314 TYR A CB  1 
ATOM 899  C CG  . TYR A 1 224 ? 105.013 130.905 152.790 1.00 77.95  ? 314 TYR A CG  1 
ATOM 900  C CD1 . TYR A 1 224 ? 105.977 131.549 152.035 1.00 77.95  ? 314 TYR A CD1 1 
ATOM 901  C CD2 . TYR A 1 224 ? 104.582 131.505 153.953 1.00 77.95  ? 314 TYR A CD2 1 
ATOM 902  C CE1 . TYR A 1 224 ? 106.495 132.742 152.427 1.00 77.95  ? 314 TYR A CE1 1 
ATOM 903  C CE2 . TYR A 1 224 ? 105.092 132.701 154.349 1.00 77.95  ? 314 TYR A CE2 1 
ATOM 904  C CZ  . TYR A 1 224 ? 106.046 133.317 153.579 1.00 77.95  ? 314 TYR A CZ  1 
ATOM 905  O OH  . TYR A 1 224 ? 106.555 134.524 153.975 1.00 77.95  ? 314 TYR A OH  1 
ATOM 906  N N   . LEU A 1 225 ? 103.983 126.993 150.910 1.00 79.30  ? 315 LEU A N   1 
ATOM 907  C CA  . LEU A 1 225 ? 104.314 125.596 150.665 1.00 79.30  ? 315 LEU A CA  1 
ATOM 908  C C   . LEU A 1 225 ? 104.668 125.370 149.210 1.00 79.30  ? 315 LEU A C   1 
ATOM 909  O O   . LEU A 1 225 ? 105.531 124.548 148.889 1.00 79.30  ? 315 LEU A O   1 
ATOM 910  C CB  . LEU A 1 225 ? 103.167 124.691 151.087 1.00 79.30  ? 315 LEU A CB  1 
ATOM 911  C CG  . LEU A 1 225 ? 103.138 124.486 152.588 1.00 79.30  ? 315 LEU A CG  1 
ATOM 912  C CD1 . LEU A 1 225 ? 101.913 123.699 152.992 1.00 79.30  ? 315 LEU A CD1 1 
ATOM 913  C CD2 . LEU A 1 225 ? 104.392 123.745 152.966 1.00 79.30  ? 315 LEU A CD2 1 
ATOM 914  N N   . LYS A 1 226 ? 104.029 126.110 148.314 1.00 77.30  ? 316 LYS A N   1 
ATOM 915  C CA  . LYS A 1 226 ? 104.438 126.022 146.923 1.00 77.30  ? 316 LYS A CA  1 
ATOM 916  C C   . LYS A 1 226 ? 105.806 126.650 146.733 1.00 77.30  ? 316 LYS A C   1 
ATOM 917  O O   . LYS A 1 226 ? 106.646 126.121 145.999 1.00 77.30  ? 316 LYS A O   1 
ATOM 918  C CB  . LYS A 1 226 ? 103.406 126.687 146.021 1.00 77.30  ? 316 LYS A CB  1 
ATOM 919  C CG  . LYS A 1 226 ? 103.616 126.379 144.555 1.00 77.30  ? 316 LYS A CG  1 
ATOM 920  C CD  . LYS A 1 226 ? 103.446 124.899 144.279 1.00 77.30  ? 316 LYS A CD  1 
ATOM 921  C CE  . LYS A 1 226 ? 102.041 124.455 144.611 1.00 77.30  ? 316 LYS A CE  1 
ATOM 922  N NZ  . LYS A 1 226 ? 101.037 125.198 143.805 1.00 77.30  ? 316 LYS A NZ  1 
ATOM 923  N N   . GLY A 1 227 ? 106.059 127.766 147.414 1.00 61.04  ? 317 GLY A N   1 
ATOM 924  C CA  . GLY A 1 227 ? 107.314 128.468 147.228 1.00 61.04  ? 317 GLY A CA  1 
ATOM 925  C C   . GLY A 1 227 ? 108.519 127.645 147.620 1.00 61.04  ? 317 GLY A C   1 
ATOM 926  O O   . GLY A 1 227 ? 109.625 127.887 147.133 1.00 61.04  ? 317 GLY A O   1 
ATOM 927  N N   . TYR A 1 228 ? 108.332 126.666 148.490 1.00 54.88  ? 318 TYR A N   1 
ATOM 928  C CA  . TYR A 1 228 ? 109.445 125.841 148.920 1.00 54.88  ? 318 TYR A CA  1 
ATOM 929  C C   . TYR A 1 228 ? 109.425 124.462 148.296 1.00 54.88  ? 318 TYR A C   1 
ATOM 930  O O   . TYR A 1 228 ? 110.163 123.587 148.753 1.00 54.88  ? 318 TYR A O   1 
ATOM 931  C CB  . TYR A 1 228 ? 109.442 125.700 150.431 1.00 54.88  ? 318 TYR A CB  1 
ATOM 932  C CG  . TYR A 1 228 ? 109.848 126.938 151.157 1.00 54.88  ? 318 TYR A CG  1 
ATOM 933  C CD1 . TYR A 1 228 ? 110.863 126.903 152.076 1.00 54.88  ? 318 TYR A CD1 1 
ATOM 934  C CD2 . TYR A 1 228 ? 109.216 128.136 150.932 1.00 54.88  ? 318 TYR A CD2 1 
ATOM 935  C CE1 . TYR A 1 228 ? 111.236 128.017 152.752 1.00 54.88  ? 318 TYR A CE1 1 
ATOM 936  C CE2 . TYR A 1 228 ? 109.586 129.257 151.601 1.00 54.88  ? 318 TYR A CE2 1 
ATOM 937  C CZ  . TYR A 1 228 ? 110.601 129.192 152.512 1.00 54.88  ? 318 TYR A CZ  1 
ATOM 938  O OH  . TYR A 1 228 ? 110.994 130.308 153.199 1.00 54.88  ? 318 TYR A OH  1 
ATOM 939  N N   . GLY A 1 229 ? 108.583 124.241 147.295 1.00 71.39  ? 319 GLY A N   1 
ATOM 940  C CA  . GLY A 1 229 ? 108.584 122.972 146.604 1.00 71.39  ? 319 GLY A CA  1 
ATOM 941  C C   . GLY A 1 229 ? 108.345 121.757 147.465 1.00 71.39  ? 319 GLY A C   1 
ATOM 942  O O   . GLY A 1 229 ? 108.818 120.674 147.125 1.00 71.39  ? 319 GLY A O   1 
ATOM 943  N N   . VAL A 1 230 ? 107.635 121.894 148.577 1.00 67.41  ? 320 VAL A N   1 
ATOM 944  C CA  . VAL A 1 230 ? 107.358 120.746 149.429 1.00 67.41  ? 320 VAL A CA  1 
ATOM 945  C C   . VAL A 1 230 ? 105.868 120.437 149.376 1.00 67.41  ? 320 VAL A C   1 
ATOM 946  O O   . VAL A 1 230 ? 105.030 121.327 149.552 1.00 67.41  ? 320 VAL A O   1 
ATOM 947  C CB  . VAL A 1 230 ? 107.828 120.999 150.862 1.00 67.41  ? 320 VAL A CB  1 
ATOM 948  C CG1 . VAL A 1 230 ? 109.323 121.175 150.867 1.00 67.41  ? 320 VAL A CG1 1 
ATOM 949  C CG2 . VAL A 1 230 ? 107.171 122.230 151.409 1.00 67.41  ? 320 VAL A CG2 1 
ATOM 950  N N   . SER A 1 231 ? 105.535 119.177 149.116 1.00 81.42  ? 321 SER A N   1 
ATOM 951  C CA  . SER A 1 231 ? 104.150 118.810 148.861 1.00 81.42  ? 321 SER A CA  1 
ATOM 952  C C   . SER A 1 231 ? 103.414 118.530 150.161 1.00 81.42  ? 321 SER A C   1 
ATOM 953  O O   . SER A 1 231 ? 103.979 117.963 151.102 1.00 81.42  ? 321 SER A O   1 
ATOM 954  C CB  . SER A 1 231 ? 104.076 117.593 147.952 1.00 81.42  ? 321 SER A CB  1 
ATOM 955  O OG  . SER A 1 231 ? 102.731 117.178 147.815 1.00 81.42  ? 321 SER A OG  1 
ATOM 956  N N   . TYR A 1 232 ? 102.148 118.911 150.196 1.00 93.57  ? 322 TYR A N   1 
ATOM 957  C CA  . TYR A 1 232 ? 101.280 118.742 151.345 1.00 93.57  ? 322 TYR A CA  1 
ATOM 958  C C   . TYR A 1 232 ? 99.986  118.089 150.899 1.00 93.57  ? 322 TYR A C   1 
ATOM 959  O O   . TYR A 1 232 ? 99.784  117.809 149.715 1.00 93.57  ? 322 TYR A O   1 
ATOM 960  C CB  . TYR A 1 232 ? 100.965 120.082 151.996 1.00 93.57  ? 322 TYR A CB  1 
ATOM 961  C CG  . TYR A 1 232 ? 100.127 120.962 151.110 1.00 93.57  ? 322 TYR A CG  1 
ATOM 962  C CD1 . TYR A 1 232 ? 100.666 121.546 149.979 1.00 93.57  ? 322 TYR A CD1 1 
ATOM 963  C CD2 . TYR A 1 232 ? 98.800  121.206 151.398 1.00 93.57  ? 322 TYR A CD2 1 
ATOM 964  C CE1 . TYR A 1 232 ? 99.910  122.347 149.165 1.00 93.57  ? 322 TYR A CE1 1 
ATOM 965  C CE2 . TYR A 1 232 ? 98.037  122.011 150.591 1.00 93.57  ? 322 TYR A CE2 1 
ATOM 966  C CZ  . TYR A 1 232 ? 98.599  122.579 149.475 1.00 93.57  ? 322 TYR A CZ  1 
ATOM 967  O OH  . TYR A 1 232 ? 97.849  123.385 148.659 1.00 93.57  ? 322 TYR A OH  1 
ATOM 968  N N   . ASP A 1 233 ? 99.099  117.862 151.858 1.00 114.10 ? 323 ASP A N   1 
ATOM 969  C CA  . ASP A 1 233 ? 97.789  117.302 151.569 1.00 114.10 ? 323 ASP A CA  1 
ATOM 970  C C   . ASP A 1 233 ? 96.735  118.393 151.673 1.00 114.10 ? 323 ASP A C   1 
ATOM 971  O O   . ASP A 1 233 ? 96.786  119.233 152.574 1.00 114.10 ? 323 ASP A O   1 
ATOM 972  C CB  . ASP A 1 233 ? 97.471  116.154 152.522 1.00 114.10 ? 323 ASP A CB  1 
ATOM 973  C CG  . ASP A 1 233 ? 98.259  114.904 152.199 1.00 114.10 ? 323 ASP A CG  1 
ATOM 974  O OD1 . ASP A 1 233 ? 99.050  114.939 151.235 1.00 114.10 ? 323 ASP A OD1 1 
ATOM 975  O OD2 . ASP A 1 233 ? 98.089  113.890 152.905 1.00 114.10 ? 323 ASP A OD2 1 
ATOM 976  N N   . GLU A 1 234 ? 95.778  118.372 150.749 1.00 122.32 ? 324 GLU A N   1 
ATOM 977  C CA  . GLU A 1 234 ? 94.767  119.415 150.668 1.00 122.32 ? 324 GLU A CA  1 
ATOM 978  C C   . GLU A 1 234 ? 93.784  119.379 151.824 1.00 122.32 ? 324 GLU A C   1 
ATOM 979  O O   . GLU A 1 234 ? 93.074  120.366 152.045 1.00 122.32 ? 324 GLU A O   1 
ATOM 980  C CB  . GLU A 1 234 ? 94.013  119.279 149.351 1.00 122.32 ? 324 GLU A CB  1 
ATOM 981  C CG  . GLU A 1 234 ? 94.863  119.582 148.137 1.00 122.32 ? 324 GLU A CG  1 
ATOM 982  C CD  . GLU A 1 234 ? 95.808  118.451 147.790 1.00 122.32 ? 324 GLU A CD  1 
ATOM 983  O OE1 . GLU A 1 234 ? 95.793  117.419 148.494 1.00 122.32 ? 324 GLU A OE1 1 
ATOM 984  O OE2 . GLU A 1 234 ? 96.569  118.599 146.813 1.00 122.32 ? 324 GLU A OE2 1 
ATOM 985  N N   . ASN A 1 235 ? 93.729  118.278 152.564 1.00 133.57 ? 325 ASN A N   1 
ATOM 986  C CA  . ASN A 1 235 ? 92.761  118.124 153.636 1.00 133.57 ? 325 ASN A CA  1 
ATOM 987  C C   . ASN A 1 235 ? 93.385  118.251 155.016 1.00 133.57 ? 325 ASN A C   1 
ATOM 988  O O   . ASN A 1 235 ? 92.744  118.785 155.927 1.00 133.57 ? 325 ASN A O   1 
ATOM 989  C CB  . ASN A 1 235 ? 92.075  116.761 153.521 1.00 133.57 ? 325 ASN A CB  1 
ATOM 990  C CG  . ASN A 1 235 ? 92.037  116.250 152.096 1.00 133.57 ? 325 ASN A CG  1 
ATOM 991  O OD1 . ASN A 1 235 ? 92.160  117.017 151.145 1.00 133.57 ? 325 ASN A OD1 1 
ATOM 992  N ND2 . ASN A 1 235 ? 91.874  114.944 151.942 1.00 133.57 ? 325 ASN A ND2 1 
ATOM 993  N N   . ASP A 1 236 ? 94.622  117.793 155.184 1.00 123.91 ? 326 ASP A N   1 
ATOM 994  C CA  . ASP A 1 236 ? 95.297  117.767 156.478 1.00 123.91 ? 326 ASP A CA  1 
ATOM 995  C C   . ASP A 1 236 ? 95.939  119.130 156.684 1.00 123.91 ? 326 ASP A C   1 
ATOM 996  O O   . ASP A 1 236 ? 97.118  119.334 156.391 1.00 123.91 ? 326 ASP A O   1 
ATOM 997  C CB  . ASP A 1 236 ? 96.331  116.628 156.535 1.00 123.91 ? 326 ASP A CB  1 
ATOM 998  C CG  . ASP A 1 236 ? 96.996  116.496 157.901 1.00 123.91 ? 326 ASP A CG  1 
ATOM 999  O OD1 . ASP A 1 236 ? 97.346  117.522 158.527 1.00 123.91 ? 326 ASP A OD1 1 
ATOM 1000 O OD2 . ASP A 1 236 ? 97.176  115.346 158.352 1.00 123.91 ? 326 ASP A OD2 1 
ATOM 1001 N N   . GLN A 1 237 ? 95.150  120.071 157.195 1.00 120.88 ? 327 GLN A N   1 
ATOM 1002 C CA  . GLN A 1 237 ? 95.718  121.337 157.623 1.00 120.88 ? 327 GLN A CA  1 
ATOM 1003 C C   . GLN A 1 237 ? 96.719  121.144 158.746 1.00 120.88 ? 327 GLN A C   1 
ATOM 1004 O O   . GLN A 1 237 ? 97.676  121.917 158.854 1.00 120.88 ? 327 GLN A O   1 
ATOM 1005 C CB  . GLN A 1 237 ? 94.601  122.270 158.071 1.00 120.88 ? 327 GLN A CB  1 
ATOM 1006 C CG  . GLN A 1 237 ? 93.324  122.068 157.298 1.00 120.88 ? 327 GLN A CG  1 
ATOM 1007 C CD  . GLN A 1 237 ? 92.445  123.292 157.318 1.00 120.88 ? 327 GLN A CD  1 
ATOM 1008 O OE1 . GLN A 1 237 ? 92.344  123.981 158.331 1.00 120.88 ? 327 GLN A OE1 1 
ATOM 1009 N NE2 . GLN A 1 237 ? 91.802  123.575 156.192 1.00 120.88 ? 327 GLN A NE2 1 
ATOM 1010 N N   . SER A 1 238 ? 96.537  120.098 159.553 1.00 122.25 ? 328 SER A N   1 
ATOM 1011 C CA  . SER A 1 238 ? 97.258  119.957 160.813 1.00 122.25 ? 328 SER A CA  1 
ATOM 1012 C C   . SER A 1 238 ? 98.765  119.917 160.628 1.00 122.25 ? 328 SER A C   1 
ATOM 1013 O O   . SER A 1 238 ? 99.506  120.207 161.571 1.00 122.25 ? 328 SER A O   1 
ATOM 1014 C CB  . SER A 1 238 ? 96.806  118.690 161.526 1.00 122.25 ? 328 SER A CB  1 
ATOM 1015 O OG  . SER A 1 238 ? 97.567  117.583 161.077 1.00 122.25 ? 328 SER A OG  1 
ATOM 1016 N N   . LEU A 1 239 ? 99.245  119.539 159.450 1.00 107.54 ? 329 LEU A N   1 
ATOM 1017 C CA  . LEU A 1 239 ? 100.682 119.373 159.311 1.00 107.54 ? 329 LEU A CA  1 
ATOM 1018 C C   . LEU A 1 239 ? 101.316 120.511 158.529 1.00 107.54 ? 329 LEU A C   1 
ATOM 1019 O O   . LEU A 1 239 ? 102.548 120.593 158.448 1.00 107.54 ? 329 LEU A O   1 
ATOM 1020 C CB  . LEU A 1 239 ? 100.983 118.028 158.664 1.00 107.54 ? 329 LEU A CB  1 
ATOM 1021 C CG  . LEU A 1 239 ? 100.598 116.833 159.535 1.00 107.54 ? 329 LEU A CG  1 
ATOM 1022 C CD1 . LEU A 1 239 ? 101.412 115.616 159.140 1.00 107.54 ? 329 LEU A CD1 1 
ATOM 1023 C CD2 . LEU A 1 239 ? 100.787 117.144 161.015 1.00 107.54 ? 329 LEU A CD2 1 
ATOM 1024 N N   . TRP A 1 240 ? 100.500 121.386 157.942 1.00 105.82 ? 330 TRP A N   1 
ATOM 1025 C CA  . TRP A 1 240 ? 101.044 122.506 157.185 1.00 105.82 ? 330 TRP A CA  1 
ATOM 1026 C C   . TRP A 1 240 ? 102.036 123.294 158.018 1.00 105.82 ? 330 TRP A C   1 
ATOM 1027 O O   . TRP A 1 240 ? 103.189 123.478 157.619 1.00 105.82 ? 330 TRP A O   1 
ATOM 1028 C CB  . TRP A 1 240 ? 99.923  123.425 156.715 1.00 105.82 ? 330 TRP A CB  1 
ATOM 1029 C CG  . TRP A 1 240 ? 98.972  122.786 155.801 1.00 105.82 ? 330 TRP A CG  1 
ATOM 1030 C CD1 . TRP A 1 240 ? 99.188  121.683 155.043 1.00 105.82 ? 330 TRP A CD1 1 
ATOM 1031 C CD2 . TRP A 1 240 ? 97.637  123.205 155.534 1.00 105.82 ? 330 TRP A CD2 1 
ATOM 1032 N NE1 . TRP A 1 240 ? 98.065  121.380 154.320 1.00 105.82 ? 330 TRP A NE1 1 
ATOM 1033 C CE2 . TRP A 1 240 ? 97.096  122.304 154.603 1.00 105.82 ? 330 TRP A CE2 1 
ATOM 1034 C CE3 . TRP A 1 240 ? 96.842  124.254 155.995 1.00 105.82 ? 330 TRP A CE3 1 
ATOM 1035 C CZ2 . TRP A 1 240 ? 95.798  122.419 154.123 1.00 105.82 ? 330 TRP A CZ2 1 
ATOM 1036 C CZ3 . TRP A 1 240 ? 95.555  124.369 155.517 1.00 105.82 ? 330 TRP A CZ3 1 
ATOM 1037 C CH2 . TRP A 1 240 ? 95.044  123.457 154.591 1.00 105.82 ? 330 TRP A CH2 1 
ATOM 1038 N N   . LYS A 1 241 ? 101.591 123.790 159.167 1.00 102.48 ? 331 LYS A N   1 
ATOM 1039 C CA  . LYS A 1 241 ? 102.421 124.695 159.943 1.00 102.48 ? 331 LYS A CA  1 
ATOM 1040 C C   . LYS A 1 241 ? 103.718 124.026 160.351 1.00 102.48 ? 331 LYS A C   1 
ATOM 1041 O O   . LYS A 1 241 ? 104.803 124.600 160.195 1.00 102.48 ? 331 LYS A O   1 
ATOM 1042 C CB  . LYS A 1 241 ? 101.648 125.173 161.165 1.00 102.48 ? 331 LYS A CB  1 
ATOM 1043 C CG  . LYS A 1 241 ? 100.374 125.910 160.828 1.00 102.48 ? 331 LYS A CG  1 
ATOM 1044 C CD  . LYS A 1 241 ? 99.793  126.571 162.059 1.00 102.48 ? 331 LYS A CD  1 
ATOM 1045 C CE  . LYS A 1 241 ? 98.681  127.538 161.710 1.00 102.48 ? 331 LYS A CE  1 
ATOM 1046 N NZ  . LYS A 1 241 ? 98.372  128.443 162.852 1.00 102.48 ? 331 LYS A NZ  1 
ATOM 1047 N N   . ARG A 1 242 ? 103.631 122.807 160.863 1.00 90.18  ? 332 ARG A N   1 
ATOM 1048 C CA  . ARG A 1 242 ? 104.850 122.131 161.259 1.00 90.18  ? 332 ARG A CA  1 
ATOM 1049 C C   . ARG A 1 242 ? 105.779 121.928 160.082 1.00 90.18  ? 332 ARG A C   1 
ATOM 1050 O O   . ARG A 1 242 ? 106.986 122.155 160.208 1.00 90.18  ? 332 ARG A O   1 
ATOM 1051 C CB  . ARG A 1 242 ? 104.530 120.792 161.915 1.00 90.18  ? 332 ARG A CB  1 
ATOM 1052 C CG  . ARG A 1 242 ? 104.381 120.879 163.419 1.00 90.18  ? 332 ARG A CG  1 
ATOM 1053 C CD  . ARG A 1 242 ? 105.727 121.035 164.096 1.00 90.18  ? 332 ARG A CD  1 
ATOM 1054 N NE  . ARG A 1 242 ? 105.587 121.557 165.449 1.00 90.18  ? 332 ARG A NE  1 
ATOM 1055 C CZ  . ARG A 1 242 ? 106.550 121.533 166.363 1.00 90.18  ? 332 ARG A CZ  1 
ATOM 1056 N NH1 . ARG A 1 242 ? 107.731 121.009 166.077 1.00 90.18  ? 332 ARG A NH1 1 
ATOM 1057 N NH2 . ARG A 1 242 ? 106.327 122.035 167.567 1.00 90.18  ? 332 ARG A NH2 1 
ATOM 1058 N N   . GLN A 1 243 ? 105.250 121.527 158.930 1.00 79.62  ? 333 GLN A N   1 
ATOM 1059 C CA  . GLN A 1 243 ? 106.148 121.216 157.832 1.00 79.62  ? 333 GLN A CA  1 
ATOM 1060 C C   . GLN A 1 243 ? 106.760 122.487 157.269 1.00 79.62  ? 333 GLN A C   1 
ATOM 1061 O O   . GLN A 1 243 ? 107.922 122.496 156.853 1.00 79.62  ? 333 GLN A O   1 
ATOM 1062 C CB  . GLN A 1 243 ? 105.411 120.418 156.763 1.00 79.62  ? 333 GLN A CB  1 
ATOM 1063 C CG  . GLN A 1 243 ? 106.349 119.638 155.866 1.00 79.62  ? 333 GLN A CG  1 
ATOM 1064 C CD  . GLN A 1 243 ? 105.691 118.426 155.246 1.00 79.62  ? 333 GLN A CD  1 
ATOM 1065 O OE1 . GLN A 1 243 ? 104.513 118.162 155.474 1.00 79.62  ? 333 GLN A OE1 1 
ATOM 1066 N NE2 . GLN A 1 243 ? 106.455 117.676 154.466 1.00 79.62  ? 333 GLN A NE2 1 
ATOM 1067 N N   . LEU A 1 244 ? 106.018 123.588 157.305 1.00 71.59  ? 334 LEU A N   1 
ATOM 1068 C CA  . LEU A 1 244 ? 106.588 124.856 156.877 1.00 71.59  ? 334 LEU A CA  1 
ATOM 1069 C C   . LEU A 1 244 ? 107.707 125.278 157.806 1.00 71.59  ? 334 LEU A C   1 
ATOM 1070 O O   . LEU A 1 244 ? 108.773 125.718 157.356 1.00 71.59  ? 334 LEU A O   1 
ATOM 1071 C CB  . LEU A 1 244 ? 105.510 125.924 156.838 1.00 71.59  ? 334 LEU A CB  1 
ATOM 1072 C CG  . LEU A 1 244 ? 106.063 127.307 156.569 1.00 71.59  ? 334 LEU A CG  1 
ATOM 1073 C CD1 . LEU A 1 244 ? 106.754 127.275 155.247 1.00 71.59  ? 334 LEU A CD1 1 
ATOM 1074 C CD2 . LEU A 1 244 ? 104.933 128.289 156.539 1.00 71.59  ? 334 LEU A CD2 1 
ATOM 1075 N N   . ALA A 1 245 ? 107.477 125.160 159.109 1.00 71.32  ? 335 ALA A N   1 
ATOM 1076 C CA  . ALA A 1 245 ? 108.545 125.408 160.061 1.00 71.32  ? 335 ALA A CA  1 
ATOM 1077 C C   . ALA A 1 245 ? 109.773 124.595 159.700 1.00 71.32  ? 335 ALA A C   1 
ATOM 1078 O O   . ALA A 1 245 ? 110.859 125.146 159.485 1.00 71.32  ? 335 ALA A O   1 
ATOM 1079 C CB  . ALA A 1 245 ? 108.074 125.074 161.472 1.00 71.32  ? 335 ALA A CB  1 
ATOM 1080 N N   . LYS A 1 246 ? 109.607 123.279 159.584 1.00 74.46  ? 336 LYS A N   1 
ATOM 1081 C CA  . LYS A 1 246 ? 110.732 122.419 159.251 1.00 74.46  ? 336 LYS A CA  1 
ATOM 1082 C C   . LYS A 1 246 ? 111.336 122.768 157.905 1.00 74.46  ? 336 LYS A C   1 
ATOM 1083 O O   . LYS A 1 246 ? 112.475 122.384 157.628 1.00 74.46  ? 336 LYS A O   1 
ATOM 1084 C CB  . LYS A 1 246 ? 110.308 120.957 159.261 1.00 74.46  ? 336 LYS A CB  1 
ATOM 1085 C CG  . LYS A 1 246 ? 110.107 120.392 160.645 1.00 74.46  ? 336 LYS A CG  1 
ATOM 1086 C CD  . LYS A 1 246 ? 110.296 118.894 160.647 1.00 74.46  ? 336 LYS A CD  1 
ATOM 1087 C CE  . LYS A 1 246 ? 109.905 118.301 161.983 1.00 74.46  ? 336 LYS A CE  1 
ATOM 1088 N NZ  . LYS A 1 246 ? 110.427 116.919 162.147 1.00 74.46  ? 336 LYS A NZ  1 
ATOM 1089 N N   . ALA A 1 247 ? 110.601 123.476 157.061 1.00 62.90  ? 337 ALA A N   1 
ATOM 1090 C CA  . ALA A 1 247 ? 111.182 123.886 155.796 1.00 62.90  ? 337 ALA A CA  1 
ATOM 1091 C C   . ALA A 1 247 ? 112.077 125.101 155.969 1.00 62.90  ? 337 ALA A C   1 
ATOM 1092 O O   . ALA A 1 247 ? 113.187 125.131 155.438 1.00 62.90  ? 337 ALA A O   1 
ATOM 1093 C CB  . ALA A 1 247 ? 110.081 124.162 154.783 1.00 62.90  ? 337 ALA A CB  1 
ATOM 1094 N N   . VAL A 1 248 ? 111.618 126.123 156.689 1.00 64.65  ? 338 VAL A N   1 
ATOM 1095 C CA  . VAL A 1 248 ? 112.467 127.300 156.849 1.00 64.65  ? 338 VAL A CA  1 
ATOM 1096 C C   . VAL A 1 248 ? 113.578 127.082 157.853 1.00 64.65  ? 338 VAL A C   1 
ATOM 1097 O O   . VAL A 1 248 ? 114.671 127.632 157.673 1.00 64.65  ? 338 VAL A O   1 
ATOM 1098 C CB  . VAL A 1 248 ? 111.698 128.557 157.273 1.00 64.65  ? 338 VAL A CB  1 
ATOM 1099 C CG1 . VAL A 1 248 ? 110.796 129.005 156.161 1.00 64.65  ? 338 VAL A CG1 1 
ATOM 1100 C CG2 . VAL A 1 248 ? 110.919 128.293 158.543 1.00 64.65  ? 338 VAL A CG2 1 
ATOM 1101 N N   . GLY A 1 249 ? 113.341 126.309 158.897 1.00 72.91  ? 339 GLY A N   1 
ATOM 1102 C CA  . GLY A 1 249 ? 114.358 126.004 159.869 1.00 72.91  ? 339 GLY A CA  1 
ATOM 1103 C C   . GLY A 1 249 ? 114.002 126.236 161.315 1.00 72.91  ? 339 GLY A C   1 
ATOM 1104 O O   . GLY A 1 249 ? 114.880 126.098 162.173 1.00 72.91  ? 339 GLY A O   1 
ATOM 1105 N N   . LEU A 1 250 ? 112.750 126.543 161.621 1.00 85.86  ? 340 LEU A N   1 
ATOM 1106 C CA  . LEU A 1 250 ? 112.358 126.775 163.004 1.00 85.86  ? 340 LEU A CA  1 
ATOM 1107 C C   . LEU A 1 250 ? 112.465 125.443 163.727 1.00 85.86  ? 340 LEU A C   1 
ATOM 1108 O O   . LEU A 1 250 ? 111.576 124.597 163.659 1.00 85.86  ? 340 LEU A O   1 
ATOM 1109 C CB  . LEU A 1 250 ? 110.955 127.347 163.074 1.00 85.86  ? 340 LEU A CB  1 
ATOM 1110 C CG  . LEU A 1 250 ? 110.942 128.853 162.872 1.00 85.86  ? 340 LEU A CG  1 
ATOM 1111 C CD1 . LEU A 1 250 ? 109.562 129.399 163.128 1.00 85.86  ? 340 LEU A CD1 1 
ATOM 1112 C CD2 . LEU A 1 250 ? 111.944 129.490 163.792 1.00 85.86  ? 340 LEU A CD2 1 
ATOM 1113 N N   . THR A 1 251 ? 113.579 125.252 164.427 1.00 88.09  ? 341 THR A N   1 
ATOM 1114 C CA  . THR A 1 251 ? 113.960 123.926 164.879 1.00 88.09  ? 341 THR A CA  1 
ATOM 1115 C C   . THR A 1 251 ? 114.230 123.840 166.377 1.00 88.09  ? 341 THR A C   1 
ATOM 1116 O O   . THR A 1 251 ? 114.359 122.730 166.901 1.00 88.09  ? 341 THR A O   1 
ATOM 1117 C CB  . THR A 1 251 ? 115.203 123.470 164.101 1.00 88.09  ? 341 THR A CB  1 
ATOM 1118 O OG1 . THR A 1 251 ? 114.970 123.671 162.705 1.00 88.09  ? 341 THR A OG1 1 
ATOM 1119 C CG2 . THR A 1 251 ? 115.464 121.993 164.307 1.00 88.09  ? 341 THR A CG2 1 
ATOM 1120 N N   . ALA A 1 252 ? 114.298 124.961 167.088 1.00 99.43  ? 342 ALA A N   1 
ATOM 1121 C CA  . ALA A 1 252 ? 114.742 124.949 168.473 1.00 99.43  ? 342 ALA A CA  1 
ATOM 1122 C C   . ALA A 1 252 ? 113.807 124.125 169.352 1.00 99.43  ? 342 ALA A C   1 
ATOM 1123 O O   . ALA A 1 252 ? 112.709 123.729 168.954 1.00 99.43  ? 342 ALA A O   1 
ATOM 1124 C CB  . ALA A 1 252 ? 114.837 126.370 169.020 1.00 99.43  ? 342 ALA A CB  1 
ATOM 1125 N N   . ALA A 1 253 ? 114.268 123.867 170.575 1.00 106.29 ? 343 ALA A N   1 
ATOM 1126 C CA  . ALA A 1 253 ? 113.456 123.126 171.530 1.00 106.29 ? 343 ALA A CA  1 
ATOM 1127 C C   . ALA A 1 253 ? 112.126 123.816 171.782 1.00 106.29 ? 343 ALA A C   1 
ATOM 1128 O O   . ALA A 1 253 ? 111.076 123.161 171.808 1.00 106.29 ? 343 ALA A O   1 
ATOM 1129 C CB  . ALA A 1 253 ? 114.221 122.947 172.841 1.00 106.29 ? 343 ALA A CB  1 
ATOM 1130 N N   . TYR A 1 254 ? 112.146 125.135 171.968 1.00 110.43 ? 344 TYR A N   1 
ATOM 1131 C CA  . TYR A 1 254 ? 110.888 125.857 172.076 1.00 110.43 ? 344 TYR A CA  1 
ATOM 1132 C C   . TYR A 1 254 ? 110.088 125.727 170.791 1.00 110.43 ? 344 TYR A C   1 
ATOM 1133 O O   . TYR A 1 254 ? 108.854 125.662 170.819 1.00 110.43 ? 344 TYR A O   1 
ATOM 1134 C CB  . TYR A 1 254 ? 111.130 127.327 172.403 1.00 110.43 ? 344 TYR A CB  1 
ATOM 1135 C CG  . TYR A 1 254 ? 109.911 128.164 172.117 1.00 110.43 ? 344 TYR A CG  1 
ATOM 1136 C CD1 . TYR A 1 254 ? 109.868 129.015 171.024 1.00 110.43 ? 344 TYR A CD1 1 
ATOM 1137 C CD2 . TYR A 1 254 ? 108.785 128.071 172.918 1.00 110.43 ? 344 TYR A CD2 1 
ATOM 1138 C CE1 . TYR A 1 254 ? 108.746 129.769 170.753 1.00 110.43 ? 344 TYR A CE1 1 
ATOM 1139 C CE2 . TYR A 1 254 ? 107.659 128.820 172.655 1.00 110.43 ? 344 TYR A CE2 1 
ATOM 1140 C CZ  . TYR A 1 254 ? 107.645 129.668 171.572 1.00 110.43 ? 344 TYR A CZ  1 
ATOM 1141 O OH  . TYR A 1 254 ? 106.524 130.416 171.308 1.00 110.43 ? 344 TYR A OH  1 
ATOM 1142 N N   . ASP A 1 255 ? 110.778 125.684 169.651 1.00 104.70 ? 345 ASP A N   1 
ATOM 1143 C CA  . ASP A 1 255 ? 110.086 125.513 168.380 1.00 104.70 ? 345 ASP A CA  1 
ATOM 1144 C C   . ASP A 1 255 ? 109.342 124.187 168.343 1.00 104.70 ? 345 ASP A C   1 
ATOM 1145 O O   . ASP A 1 255 ? 108.334 124.049 167.642 1.00 104.70 ? 345 ASP A O   1 
ATOM 1146 C CB  . ASP A 1 255 ? 111.077 125.595 167.226 1.00 104.70 ? 345 ASP A CB  1 
ATOM 1147 C CG  . ASP A 1 255 ? 111.790 126.920 167.174 1.00 104.70 ? 345 ASP A CG  1 
ATOM 1148 O OD1 . ASP A 1 255 ? 111.236 127.913 167.689 1.00 104.70 ? 345 ASP A OD1 1 
ATOM 1149 O OD2 . ASP A 1 255 ? 112.899 126.969 166.605 1.00 104.70 ? 345 ASP A OD2 1 
ATOM 1150 N N   . ALA A 1 256 ? 109.828 123.196 169.088 1.00 108.88 ? 346 ALA A N   1 
ATOM 1151 C CA  . ALA A 1 256 ? 109.092 121.947 169.202 1.00 108.88 ? 346 ALA A CA  1 
ATOM 1152 C C   . ALA A 1 256 ? 107.974 122.037 170.227 1.00 108.88 ? 346 ALA A C   1 
ATOM 1153 O O   . ALA A 1 256 ? 106.873 121.540 169.969 1.00 108.88 ? 346 ALA A O   1 
ATOM 1154 C CB  . ALA A 1 256 ? 110.039 120.810 169.554 1.00 50.00  ? 346 ALA A CB  1 
ATOM 1155 N N   . SER A 1 257 ? 108.220 122.678 171.367 1.00 113.34 ? 347 SER A N   1 
ATOM 1156 C CA  . SER A 1 257 ? 107.241 122.689 172.445 1.00 113.34 ? 347 SER A CA  1 
ATOM 1157 C C   . SER A 1 257 ? 106.044 123.586 172.166 1.00 113.34 ? 347 SER A C   1 
ATOM 1158 O O   . SER A 1 257 ? 104.998 123.404 172.795 1.00 113.34 ? 347 SER A O   1 
ATOM 1159 C CB  . SER A 1 257 ? 107.904 123.127 173.750 1.00 113.34 ? 347 SER A CB  1 
ATOM 1160 O OG  . SER A 1 257 ? 108.713 124.267 173.541 1.00 113.34 ? 347 SER A OG  1 
ATOM 1161 N N   . TYR A 1 258 ? 106.164 124.541 171.253 1.00 116.08 ? 348 TYR A N   1 
ATOM 1162 C CA  . TYR A 1 258 ? 105.056 125.436 170.958 1.00 116.08 ? 348 TYR A CA  1 
ATOM 1163 C C   . TYR A 1 258 ? 103.960 124.673 170.229 1.00 116.08 ? 348 TYR A C   1 
ATOM 1164 O O   . TYR A 1 258 ? 104.242 123.738 169.475 1.00 116.08 ? 348 TYR A O   1 
ATOM 1165 C CB  . TYR A 1 258 ? 105.541 126.611 170.120 1.00 116.08 ? 348 TYR A CB  1 
ATOM 1166 C CG  . TYR A 1 258 ? 104.446 127.527 169.634 1.00 116.08 ? 348 TYR A CG  1 
ATOM 1167 C CD1 . TYR A 1 258 ? 103.814 127.304 168.419 1.00 116.08 ? 348 TYR A CD1 1 
ATOM 1168 C CD2 . TYR A 1 258 ? 104.050 128.618 170.388 1.00 116.08 ? 348 TYR A CD2 1 
ATOM 1169 C CE1 . TYR A 1 258 ? 102.827 128.142 167.969 1.00 116.08 ? 348 TYR A CE1 1 
ATOM 1170 C CE2 . TYR A 1 258 ? 103.056 129.460 169.947 1.00 116.08 ? 348 TYR A CE2 1 
ATOM 1171 C CZ  . TYR A 1 258 ? 102.447 129.216 168.739 1.00 116.08 ? 348 TYR A CZ  1 
ATOM 1172 O OH  . TYR A 1 258 ? 101.455 130.057 168.296 1.00 116.08 ? 348 TYR A OH  1 
ATOM 1173 N N   . THR A 1 259 ? 102.711 125.068 170.456 1.00 118.88 ? 349 THR A N   1 
ATOM 1174 C CA  . THR A 1 259 ? 101.569 124.430 169.806 1.00 118.88 ? 349 THR A CA  1 
ATOM 1175 C C   . THR A 1 259 ? 100.955 125.405 168.811 1.00 118.88 ? 349 THR A C   1 
ATOM 1176 O O   . THR A 1 259 ? 100.640 126.550 169.133 1.00 118.88 ? 349 THR A O   1 
ATOM 1177 C CB  . THR A 1 259 ? 100.553 123.956 170.839 1.00 118.88 ? 349 THR A CB  1 
ATOM 1178 O OG1 . THR A 1 259 ? 99.430  123.372 170.168 1.00 118.88 ? 349 THR A OG1 1 
ATOM 1179 C CG2 . THR A 1 259 ? 100.088 125.105 171.728 1.00 118.88 ? 349 THR A CG2 1 
ATOM 1180 N N   . PHE A 1 260 ? 100.790 124.939 167.578 1.00 117.62 ? 350 PHE A N   1 
ATOM 1181 C CA  . PHE A 1 260 ? 100.181 125.761 166.544 1.00 117.62 ? 350 PHE A CA  1 
ATOM 1182 C C   . PHE A 1 260 ? 98.708  125.996 166.841 1.00 117.62 ? 350 PHE A C   1 
ATOM 1183 O O   . PHE A 1 260 ? 98.050  125.183 167.495 1.00 117.62 ? 350 PHE A O   1 
ATOM 1184 C CB  . PHE A 1 260 ? 100.334 125.093 165.181 1.00 117.62 ? 350 PHE A CB  1 
ATOM 1185 C CG  . PHE A 1 260 ? 101.714 125.200 164.606 1.00 117.62 ? 350 PHE A CG  1 
ATOM 1186 C CD1 . PHE A 1 260 ? 102.295 126.435 164.393 1.00 117.62 ? 350 PHE A CD1 1 
ATOM 1187 C CD2 . PHE A 1 260 ? 102.431 124.064 164.276 1.00 117.62 ? 350 PHE A CD2 1 
ATOM 1188 C CE1 . PHE A 1 260 ? 103.561 126.532 163.860 1.00 117.62 ? 350 PHE A CE1 1 
ATOM 1189 C CE2 . PHE A 1 260 ? 103.695 124.159 163.745 1.00 117.62 ? 350 PHE A CE2 1 
ATOM 1190 C CZ  . PHE A 1 260 ? 104.261 125.392 163.535 1.00 117.62 ? 350 PHE A CZ  1 
ATOM 1191 N N   . SER A 1 261 ? 98.193  127.118 166.358 1.00 121.52 ? 351 SER A N   1 
ATOM 1192 C CA  . SER A 1 261 ? 96.780  127.406 166.518 1.00 121.52 ? 351 SER A CA  1 
ATOM 1193 C C   . SER A 1 261 ? 96.017  126.976 165.270 1.00 121.52 ? 351 SER A C   1 
ATOM 1194 O O   . SER A 1 261 ? 96.607  126.863 164.190 1.00 121.52 ? 351 SER A O   1 
ATOM 1195 C CB  . SER A 1 261 ? 96.565  128.895 166.776 1.00 121.52 ? 351 SER A CB  1 
ATOM 1196 O OG  . SER A 1 261 ? 97.309  129.679 165.861 1.00 121.52 ? 351 SER A OG  1 
ATOM 1197 N N   . PRO A 1 262 ? 94.717  126.715 165.377 1.00 123.43 ? 352 PRO A N   1 
ATOM 1198 C CA  . PRO A 1 262 ? 93.925  126.398 164.185 1.00 123.43 ? 352 PRO A CA  1 
ATOM 1199 C C   . PRO A 1 262 ? 93.542  127.658 163.426 1.00 123.43 ? 352 PRO A C   1 
ATOM 1200 O O   . PRO A 1 262 ? 93.650  128.782 163.922 1.00 123.43 ? 352 PRO A O   1 
ATOM 1201 C CB  . PRO A 1 262 ? 92.696  125.693 164.757 1.00 123.43 ? 352 PRO A CB  1 
ATOM 1202 C CG  . PRO A 1 262 ? 92.536  126.303 166.105 1.00 123.43 ? 352 PRO A CG  1 
ATOM 1203 C CD  . PRO A 1 262 ? 93.927  126.578 166.614 1.00 123.43 ? 352 PRO A CD  1 
ATOM 1204 N N   . PHE A 1 263 ? 93.077  127.458 162.198 1.00 127.08 ? 353 PHE A N   1 
ATOM 1205 C CA  . PHE A 1 263 ? 92.686  128.580 161.363 1.00 127.08 ? 353 PHE A CA  1 
ATOM 1206 C C   . PHE A 1 263 ? 91.314  129.108 161.763 1.00 127.08 ? 353 PHE A C   1 
ATOM 1207 O O   . PHE A 1 263 ? 90.629  128.557 162.627 1.00 127.08 ? 353 PHE A O   1 
ATOM 1208 C CB  . PHE A 1 263 ? 92.670  128.178 159.893 1.00 127.08 ? 353 PHE A CB  1 
ATOM 1209 C CG  . PHE A 1 263 ? 94.027  127.938 159.329 1.00 127.08 ? 353 PHE A CG  1 
ATOM 1210 C CD1 . PHE A 1 263 ? 94.992  128.924 159.391 1.00 127.08 ? 353 PHE A CD1 1 
ATOM 1211 C CD2 . PHE A 1 263 ? 94.343  126.729 158.743 1.00 127.08 ? 353 PHE A CD2 1 
ATOM 1212 C CE1 . PHE A 1 263 ? 96.246  128.710 158.877 1.00 127.08 ? 353 PHE A CE1 1 
ATOM 1213 C CE2 . PHE A 1 263 ? 95.595  126.509 158.226 1.00 127.08 ? 353 PHE A CE2 1 
ATOM 1214 C CZ  . PHE A 1 263 ? 96.550  127.500 158.293 1.00 127.08 ? 353 PHE A CZ  1 
ATOM 1215 N N   . SER A 1 264 ? 90.917  130.195 161.110 1.00 144.33 ? 354 SER A N   1 
ATOM 1216 C CA  . SER A 1 264 ? 89.626  130.821 161.368 1.00 144.33 ? 354 SER A CA  1 
ATOM 1217 C C   . SER A 1 264 ? 88.495  130.055 160.692 1.00 144.33 ? 354 SER A C   1 
ATOM 1218 O O   . SER A 1 264 ? 87.523  130.651 160.227 1.00 144.33 ? 354 SER A O   1 
ATOM 1219 C CB  . SER A 1 264 ? 89.633  132.273 160.888 1.00 144.33 ? 354 SER A CB  1 
ATOM 1220 O OG  . SER A 1 264 ? 89.251  132.359 159.527 1.00 144.33 ? 354 SER A OG  1 
ATOM 1221 N N   . MET B 1 118 ? 123.598 121.552 69.899  1.00 179.57 ? 208 MET B N   1 
ATOM 1222 C CA  . MET B 1 118 ? 123.047 122.762 70.497  1.00 179.57 ? 208 MET B CA  1 
ATOM 1223 C C   . MET B 1 118 ? 121.791 122.446 71.302  1.00 179.57 ? 208 MET B C   1 
ATOM 1224 O O   . MET B 1 118 ? 121.524 123.074 72.336  1.00 179.57 ? 208 MET B O   1 
ATOM 1225 C CB  . MET B 1 118 ? 122.737 123.802 69.420  1.00 50.00  ? 208 MET B CB  1 
ATOM 1226 C CG  . MET B 1 118 ? 123.964 124.346 68.707  1.00 50.00  ? 208 MET B CG  1 
ATOM 1227 S SD  . MET B 1 118 ? 125.118 125.156 69.830  1.00 50.00  ? 208 MET B SD  1 
ATOM 1228 C CE  . MET B 1 118 ? 124.157 126.581 70.333  1.00 50.00  ? 208 MET B CE  1 
ATOM 1229 N N   . GLY B 1 119 ? 121.013 121.460 70.848  1.00 177.64 ? 209 GLY B N   1 
ATOM 1230 C CA  . GLY B 1 119 ? 119.942 120.931 71.686  1.00 177.64 ? 209 GLY B CA  1 
ATOM 1231 C C   . GLY B 1 119 ? 120.483 120.556 73.054  1.00 177.64 ? 209 GLY B C   1 
ATOM 1232 O O   . GLY B 1 119 ? 120.088 121.133 74.077  1.00 177.64 ? 209 GLY B O   1 
ATOM 1233 N N   . GLU B 1 120 ? 121.423 119.608 73.076  1.00 171.52 ? 210 GLU B N   1 
ATOM 1234 C CA  . GLU B 1 120 ? 122.017 119.160 74.326  1.00 171.52 ? 210 GLU B CA  1 
ATOM 1235 C C   . GLU B 1 120 ? 122.522 120.330 75.151  1.00 171.52 ? 210 GLU B C   1 
ATOM 1236 O O   . GLU B 1 120 ? 122.376 120.331 76.376  1.00 171.52 ? 210 GLU B O   1 
ATOM 1237 C CB  . GLU B 1 120 ? 123.159 118.179 74.052  1.00 50.00  ? 210 GLU B CB  1 
ATOM 1238 C CG  . GLU B 1 120 ? 122.711 116.857 73.449  1.00 50.00  ? 210 GLU B CG  1 
ATOM 1239 C CD  . GLU B 1 120 ? 123.877 115.942 73.126  1.00 50.00  ? 210 GLU B CD  1 
ATOM 1240 O OE1 . GLU B 1 120 ? 125.035 116.405 73.192  1.00 50.00  ? 210 GLU B OE1 1 
ATOM 1241 O OE2 . GLU B 1 120 ? 123.635 114.760 72.802  1.00 50.00  ? 210 GLU B OE2 1 
ATOM 1242 N N   . TRP B 1 121 ? 123.121 121.324 74.497  1.00 167.89 ? 211 TRP B N   1 
ATOM 1243 C CA  . TRP B 1 121 ? 123.496 122.548 75.191  1.00 167.89 ? 211 TRP B CA  1 
ATOM 1244 C C   . TRP B 1 121 ? 122.304 123.136 75.928  1.00 167.89 ? 211 TRP B C   1 
ATOM 1245 O O   . TRP B 1 121 ? 122.406 123.501 77.103  1.00 167.89 ? 211 TRP B O   1 
ATOM 1246 C CB  . TRP B 1 121 ? 124.065 123.572 74.207  1.00 50.00  ? 211 TRP B CB  1 
ATOM 1247 C CG  . TRP B 1 121 ? 125.401 123.188 73.648  1.00 50.00  ? 211 TRP B CG  1 
ATOM 1248 C CD1 . TRP B 1 121 ? 125.644 122.542 72.470  1.00 50.00  ? 211 TRP B CD1 1 
ATOM 1249 C CD2 . TRP B 1 121 ? 126.682 123.426 74.244  1.00 50.00  ? 211 TRP B CD2 1 
ATOM 1250 N NE1 . TRP B 1 121 ? 126.995 122.362 72.298  1.00 50.00  ? 211 TRP B NE1 1 
ATOM 1251 C CE2 . TRP B 1 121 ? 127.655 122.897 73.372  1.00 50.00  ? 211 TRP B CE2 1 
ATOM 1252 C CE3 . TRP B 1 121 ? 127.108 124.033 75.431  1.00 50.00  ? 211 TRP B CE3 1 
ATOM 1253 C CZ2 . TRP B 1 121 ? 129.020 122.956 73.648  1.00 50.00  ? 211 TRP B CZ2 1 
ATOM 1254 C CZ3 . TRP B 1 121 ? 128.463 124.091 75.701  1.00 50.00  ? 211 TRP B CZ3 1 
ATOM 1255 C CH2 . TRP B 1 121 ? 129.402 123.556 74.815  1.00 50.00  ? 211 TRP B CH2 1 
ATOM 1256 N N   . LYS B 1 122 ? 121.161 123.222 75.252  1.00 164.91 ? 212 LYS B N   1 
ATOM 1257 C CA  . LYS B 1 122 ? 119.980 123.805 75.871  1.00 164.91 ? 212 LYS B CA  1 
ATOM 1258 C C   . LYS B 1 122 ? 119.469 122.983 77.045  1.00 164.91 ? 212 LYS B C   1 
ATOM 1259 O O   . LYS B 1 122 ? 119.206 123.546 78.117  1.00 164.91 ? 212 LYS B O   1 
ATOM 1260 C CB  . LYS B 1 122 ? 118.869 123.967 74.833  1.00 50.00  ? 212 LYS B CB  1 
ATOM 1261 C CG  . LYS B 1 122 ? 119.179 124.982 73.743  1.00 50.00  ? 212 LYS B CG  1 
ATOM 1262 C CD  . LYS B 1 122 ? 118.046 125.075 72.735  1.00 50.00  ? 212 LYS B CD  1 
ATOM 1263 C CE  . LYS B 1 122 ? 118.346 126.106 71.660  1.00 50.00  ? 212 LYS B CE  1 
ATOM 1264 N NZ  . LYS B 1 122 ? 117.255 126.190 70.651  1.00 50.00  ? 212 LYS B NZ  1 
ATOM 1265 N N   . LYS B 1 123 ? 119.317 121.671 76.867  1.00 155.98 ? 213 LYS B N   1 
ATOM 1266 C CA  . LYS B 1 123 ? 118.848 120.872 77.995  1.00 155.98 ? 213 LYS B CA  1 
ATOM 1267 C C   . LYS B 1 123 ? 119.847 120.913 79.140  1.00 155.98 ? 213 LYS B C   1 
ATOM 1268 O O   . LYS B 1 123 ? 119.460 120.865 80.315  1.00 155.98 ? 213 LYS B O   1 
ATOM 1269 C CB  . LYS B 1 123 ? 118.600 119.426 77.563  1.00 50.00  ? 213 LYS B CB  1 
ATOM 1270 C CG  . LYS B 1 123 ? 117.443 119.257 76.591  1.00 50.00  ? 213 LYS B CG  1 
ATOM 1271 C CD  . LYS B 1 123 ? 117.268 117.803 76.186  1.00 50.00  ? 213 LYS B CD  1 
ATOM 1272 C CE  . LYS B 1 123 ? 116.097 117.631 75.233  1.00 50.00  ? 213 LYS B CE  1 
ATOM 1273 N NZ  . LYS B 1 123 ? 115.930 116.214 74.809  1.00 50.00  ? 213 LYS B NZ  1 
ATOM 1274 N N   . ALA B 1 124 ? 121.118 120.888 78.775  1.00 154.06 ? 214 ALA B N   1 
ATOM 1275 C CA  . ALA B 1 124 ? 122.137 120.905 79.780  1.00 154.06 ? 214 ALA B CA  1 
ATOM 1276 C C   . ALA B 1 124 ? 121.991 122.189 80.506  1.00 154.06 ? 214 ALA B C   1 
ATOM 1277 O O   . ALA B 1 124 ? 122.119 122.264 81.745  1.00 154.06 ? 214 ALA B O   1 
ATOM 1278 C CB  . ALA B 1 124 ? 123.524 120.755 79.175  1.00 50.00  ? 214 ALA B CB  1 
ATOM 1279 N N   . ARG B 1 125 ? 121.769 123.252 79.742  1.00 144.30 ? 215 ARG B N   1 
ATOM 1280 C CA  . ARG B 1 125 ? 121.606 124.561 80.338  1.00 144.30 ? 215 ARG B CA  1 
ATOM 1281 C C   . ARG B 1 125 ? 120.501 124.507 81.354  1.00 144.30 ? 215 ARG B C   1 
ATOM 1282 O O   . ARG B 1 125 ? 120.632 125.033 82.459  1.00 144.30 ? 215 ARG B O   1 
ATOM 1283 C CB  . ARG B 1 125 ? 121.237 125.586 79.271  1.00 50.00  ? 215 ARG B CB  1 
ATOM 1284 C CG  . ARG B 1 125 ? 122.253 126.690 79.055  1.00 50.00  ? 215 ARG B CG  1 
ATOM 1285 C CD  . ARG B 1 125 ? 121.548 127.964 78.616  1.00 50.00  ? 215 ARG B CD  1 
ATOM 1286 N NE  . ARG B 1 125 ? 122.464 128.933 78.027  1.00 50.00  ? 215 ARG B NE  1 
ATOM 1287 C CZ  . ARG B 1 125 ? 123.180 129.810 78.720  1.00 50.00  ? 215 ARG B CZ  1 
ATOM 1288 N NH1 . ARG B 1 125 ? 123.093 129.845 80.043  1.00 50.00  ? 215 ARG B NH1 1 
ATOM 1289 N NH2 . ARG B 1 125 ? 123.986 130.653 78.090  1.00 50.00  ? 215 ARG B NH2 1 
ATOM 1290 N N   . GLU B 1 126 ? 119.397 123.870 80.988  1.00 138.50 ? 216 GLU B N   1 
ATOM 1291 C CA  . GLU B 1 126 ? 118.261 123.865 81.890  1.00 138.50 ? 216 GLU B CA  1 
ATOM 1292 C C   . GLU B 1 126 ? 118.573 123.125 83.172  1.00 138.50 ? 216 GLU B C   1 
ATOM 1293 O O   . GLU B 1 126 ? 118.297 123.623 84.262  1.00 138.50 ? 216 GLU B O   1 
ATOM 1294 C CB  . GLU B 1 126 ? 117.042 123.240 81.208  1.00 50.00  ? 216 GLU B CB  1 
ATOM 1295 C CG  . GLU B 1 126 ? 116.494 124.055 80.047  1.00 50.00  ? 216 GLU B CG  1 
ATOM 1296 C CD  . GLU B 1 126 ? 115.333 123.369 79.352  1.00 50.00  ? 216 GLU B CD  1 
ATOM 1297 O OE1 . GLU B 1 126 ? 115.079 122.183 79.648  1.00 50.00  ? 216 GLU B OE1 1 
ATOM 1298 O OE2 . GLU B 1 126 ? 114.678 124.015 78.508  1.00 50.00  ? 216 GLU B OE2 1 
ATOM 1299 N N   . GLU B 1 127 ? 119.168 121.944 83.040  1.00 137.74 ? 217 GLU B N   1 
ATOM 1300 C CA  . GLU B 1 127 ? 119.548 121.168 84.209  1.00 137.74 ? 217 GLU B CA  1 
ATOM 1301 C C   . GLU B 1 127 ? 120.331 122.025 85.170  1.00 137.74 ? 217 GLU B C   1 
ATOM 1302 O O   . GLU B 1 127 ? 120.090 121.999 86.375  1.00 137.74 ? 217 GLU B O   1 
ATOM 1303 C CB  . GLU B 1 127 ? 120.407 119.983 83.789  1.00 50.00  ? 217 GLU B CB  1 
ATOM 1304 C CG  . GLU B 1 127 ? 119.770 119.101 82.733  1.00 50.00  ? 217 GLU B CG  1 
ATOM 1305 C CD  . GLU B 1 127 ? 120.791 118.505 81.786  1.00 50.00  ? 217 GLU B CD  1 
ATOM 1306 O OE1 . GLU B 1 127 ? 122.001 118.587 82.085  1.00 50.00  ? 217 GLU B OE1 1 
ATOM 1307 O OE2 . GLU B 1 127 ? 120.385 117.961 80.738  1.00 50.00  ? 217 GLU B OE2 1 
ATOM 1308 N N   . ASP B 1 128 ? 121.270 122.797 84.639  1.00 133.47 ? 218 ASP B N   1 
ATOM 1309 C CA  . ASP B 1 128 ? 122.112 123.606 85.500  1.00 133.47 ? 218 ASP B CA  1 
ATOM 1310 C C   . ASP B 1 128 ? 121.257 124.606 86.240  1.00 133.47 ? 218 ASP B C   1 
ATOM 1311 O O   . ASP B 1 128 ? 121.449 124.825 87.428  1.00 133.47 ? 218 ASP B O   1 
ATOM 1312 C CB  . ASP B 1 128 ? 123.169 124.330 84.675  1.00 50.00  ? 218 ASP B CB  1 
ATOM 1313 C CG  . ASP B 1 128 ? 124.003 123.380 83.843  1.00 50.00  ? 218 ASP B CG  1 
ATOM 1314 O OD1 . ASP B 1 128 ? 123.966 122.161 84.113  1.00 50.00  ? 218 ASP B OD1 1 
ATOM 1315 O OD2 . ASP B 1 128 ? 124.698 123.850 82.919  1.00 50.00  ? 218 ASP B OD2 1 
ATOM 1316 N N   . LYS B 1 129 ? 120.289 125.191 85.546  1.00 129.14 ? 219 LYS B N   1 
ATOM 1317 C CA  . LYS B 1 129 ? 119.389 126.133 86.190  1.00 129.14 ? 219 LYS B CA  1 
ATOM 1318 C C   . LYS B 1 129 ? 118.713 125.450 87.361  1.00 129.14 ? 219 LYS B C   1 
ATOM 1319 O O   . LYS B 1 129 ? 118.644 126.005 88.455  1.00 129.14 ? 219 LYS B O   1 
ATOM 1320 C CB  . LYS B 1 129 ? 118.367 126.647 85.185  1.00 50.00  ? 219 LYS B CB  1 
ATOM 1321 C CG  . LYS B 1 129 ? 119.013 127.314 83.983  1.00 50.00  ? 219 LYS B CG  1 
ATOM 1322 C CD  . LYS B 1 129 ? 118.146 127.191 82.743  1.00 50.00  ? 219 LYS B CD  1 
ATOM 1323 C CE  . LYS B 1 129 ? 118.912 127.618 81.502  1.00 50.00  ? 219 LYS B CE  1 
ATOM 1324 N NZ  . LYS B 1 129 ? 118.234 127.173 80.254  1.00 50.00  ? 219 LYS B NZ  1 
ATOM 1325 N N   . GLU B 1 130 ? 118.209 124.242 87.143  1.00 135.55 ? 220 GLU B N   1 
ATOM 1326 C CA  . GLU B 1 130 ? 117.624 123.493 88.249  1.00 135.55 ? 220 GLU B CA  1 
ATOM 1327 C C   . GLU B 1 130 ? 118.667 123.235 89.326  1.00 135.55 ? 220 GLU B C   1 
ATOM 1328 O O   . GLU B 1 130 ? 118.399 123.407 90.521  1.00 135.55 ? 220 GLU B O   1 
ATOM 1329 C CB  . GLU B 1 130 ? 116.998 122.183 87.768  1.00 135.55 ? 220 GLU B CB  1 
ATOM 1330 C CG  . GLU B 1 130 ? 115.627 122.352 87.116  1.00 135.55 ? 220 GLU B CG  1 
ATOM 1331 C CD  . GLU B 1 130 ? 115.683 122.479 85.613  1.00 135.55 ? 220 GLU B CD  1 
ATOM 1332 O OE1 . GLU B 1 130 ? 116.599 121.897 85.012  1.00 135.55 ? 220 GLU B OE1 1 
ATOM 1333 O OE2 . GLU B 1 130 ? 114.813 123.158 85.032  1.00 135.55 ? 220 GLU B OE2 1 
ATOM 1334 N N   . TRP B 1 131 ? 119.873 122.849 88.914  1.00 116.35 ? 221 TRP B N   1 
ATOM 1335 C CA  . TRP B 1 131 ? 120.966 122.700 89.861  1.00 116.35 ? 221 TRP B CA  1 
ATOM 1336 C C   . TRP B 1 131 ? 121.173 123.976 90.654  1.00 116.35 ? 221 TRP B C   1 
ATOM 1337 O O   . TRP B 1 131 ? 121.431 123.933 91.865  1.00 116.35 ? 221 TRP B O   1 
ATOM 1338 C CB  . TRP B 1 131 ? 122.239 122.322 89.114  1.00 116.35 ? 221 TRP B CB  1 
ATOM 1339 C CG  . TRP B 1 131 ? 123.426 122.333 89.975  1.00 116.35 ? 221 TRP B CG  1 
ATOM 1340 C CD1 . TRP B 1 131 ? 123.696 121.488 91.003  1.00 116.35 ? 221 TRP B CD1 1 
ATOM 1341 C CD2 . TRP B 1 131 ? 124.513 123.251 89.911  1.00 116.35 ? 221 TRP B CD2 1 
ATOM 1342 N NE1 . TRP B 1 131 ? 124.894 121.814 91.576  1.00 116.35 ? 221 TRP B NE1 1 
ATOM 1343 C CE2 . TRP B 1 131 ? 125.416 122.898 90.923  1.00 116.35 ? 221 TRP B CE2 1 
ATOM 1344 C CE3 . TRP B 1 131 ? 124.813 124.336 89.090  1.00 116.35 ? 221 TRP B CE3 1 
ATOM 1345 C CZ2 . TRP B 1 131 ? 126.594 123.591 91.139  1.00 116.35 ? 221 TRP B CZ2 1 
ATOM 1346 C CZ3 . TRP B 1 131 ? 125.988 125.018 89.304  1.00 116.35 ? 221 TRP B CZ3 1 
ATOM 1347 C CH2 . TRP B 1 131 ? 126.864 124.644 90.318  1.00 116.35 ? 221 TRP B CH2 1 
ATOM 1348 N N   . ARG B 1 132 ? 121.045 125.115 89.984  1.00 117.19 ? 222 ARG B N   1 
ATOM 1349 C CA  . ARG B 1 132 ? 121.136 126.392 90.668  1.00 117.19 ? 222 ARG B CA  1 
ATOM 1350 C C   . ARG B 1 132 ? 120.086 126.485 91.759  1.00 117.19 ? 222 ARG B C   1 
ATOM 1351 O O   . ARG B 1 132 ? 120.349 126.999 92.846  1.00 117.19 ? 222 ARG B O   1 
ATOM 1352 C CB  . ARG B 1 132 ? 120.966 127.546 89.684  1.00 117.19 ? 222 ARG B CB  1 
ATOM 1353 C CG  . ARG B 1 132 ? 121.886 127.534 88.494  1.00 117.19 ? 222 ARG B CG  1 
ATOM 1354 C CD  . ARG B 1 132 ? 121.828 128.883 87.809  1.00 117.19 ? 222 ARG B CD  1 
ATOM 1355 N NE  . ARG B 1 132 ? 121.903 128.786 86.359  1.00 117.19 ? 222 ARG B NE  1 
ATOM 1356 C CZ  . ARG B 1 132 ? 123.038 128.804 85.677  1.00 117.19 ? 222 ARG B CZ  1 
ATOM 1357 N NH1 . ARG B 1 132 ? 124.191 128.895 86.321  1.00 117.19 ? 222 ARG B NH1 1 
ATOM 1358 N NH2 . ARG B 1 132 ? 123.022 128.716 84.357  1.00 117.19 ? 222 ARG B NH2 1 
ATOM 1359 N N   . LYS B 1 133 ? 118.877 126.001 91.482  1.00 117.93 ? 223 LYS B N   1 
ATOM 1360 C CA  . LYS B 1 133 ? 117.804 126.132 92.458  1.00 117.93 ? 223 LYS B CA  1 
ATOM 1361 C C   . LYS B 1 133 ? 118.106 125.325 93.711  1.00 117.93 ? 223 LYS B C   1 
ATOM 1362 O O   . LYS B 1 133 ? 117.918 125.807 94.835  1.00 117.93 ? 223 LYS B O   1 
ATOM 1363 C CB  . LYS B 1 133 ? 116.475 125.709 91.832  1.00 117.93 ? 223 LYS B CB  1 
ATOM 1364 C CG  . LYS B 1 133 ? 115.650 126.891 91.328  1.00 117.93 ? 223 LYS B CG  1 
ATOM 1365 C CD  . LYS B 1 133 ? 114.212 126.503 91.018  1.00 117.93 ? 223 LYS B CD  1 
ATOM 1366 C CE  . LYS B 1 133 ? 113.438 127.684 90.449  1.00 117.93 ? 223 LYS B CE  1 
ATOM 1367 N NZ  . LYS B 1 133 ? 114.095 128.264 89.250  1.00 117.93 ? 223 LYS B NZ  1 
ATOM 1368 N N   . SER B 1 134 ? 118.553 124.083 93.534  1.00 110.25 ? 224 SER B N   1 
ATOM 1369 C CA  . SER B 1 134 ? 118.996 123.292 94.673  1.00 110.25 ? 224 SER B CA  1 
ATOM 1370 C C   . SER B 1 134 ? 120.071 124.017 95.456  1.00 110.25 ? 224 SER B C   1 
ATOM 1371 O O   . SER B 1 134 ? 119.988 124.118 96.690  1.00 110.25 ? 224 SER B O   1 
ATOM 1372 C CB  . SER B 1 134 ? 119.531 121.940 94.202  1.00 110.25 ? 224 SER B CB  1 
ATOM 1373 O OG  . SER B 1 134 ? 120.917 122.023 93.914  1.00 110.25 ? 224 SER B OG  1 
ATOM 1374 N N   . THR B 1 135 ? 121.083 124.514 94.753  1.00 107.23 ? 225 THR B N   1 
ATOM 1375 C CA  . THR B 1 135 ? 122.126 125.274 95.415  1.00 107.23 ? 225 THR B CA  1 
ATOM 1376 C C   . THR B 1 135 ? 121.526 126.415 96.218  1.00 107.23 ? 225 THR B C   1 
ATOM 1377 O O   . THR B 1 135 ? 121.874 126.624 97.384  1.00 107.23 ? 225 THR B O   1 
ATOM 1378 C CB  . THR B 1 135 ? 123.102 125.799 94.374  1.00 107.23 ? 225 THR B CB  1 
ATOM 1379 O OG1 . THR B 1 135 ? 123.327 124.781 93.392  1.00 107.23 ? 225 THR B OG1 1 
ATOM 1380 C CG2 . THR B 1 135 ? 124.413 126.157 95.025  1.00 107.23 ? 225 THR B CG2 1 
ATOM 1381 N N   . ASP B 1 136 ? 120.588 127.136 95.617  1.00 114.17 ? 226 ASP B N   1 
ATOM 1382 C CA  . ASP B 1 136 ? 120.018 128.311 96.255  1.00 114.17 ? 226 ASP B CA  1 
ATOM 1383 C C   . ASP B 1 136 ? 119.277 127.950 97.526  1.00 114.17 ? 226 ASP B C   1 
ATOM 1384 O O   . ASP B 1 136 ? 119.431 128.618 98.557  1.00 114.17 ? 226 ASP B O   1 
ATOM 1385 C CB  . ASP B 1 136 ? 119.075 129.016 95.289  1.00 114.17 ? 226 ASP B CB  1 
ATOM 1386 C CG  . ASP B 1 136 ? 118.481 130.267 95.880  1.00 114.17 ? 226 ASP B CG  1 
ATOM 1387 O OD1 . ASP B 1 136 ? 117.419 130.159 96.523  1.00 114.17 ? 226 ASP B OD1 1 
ATOM 1388 O OD2 . ASP B 1 136 ? 119.070 131.355 95.713  1.00 114.17 ? 226 ASP B OD2 1 
ATOM 1389 N N   . GLU B 1 137 ? 118.452 126.908 97.466  1.00 122.52 ? 227 GLU B N   1 
ATOM 1390 C CA  . GLU B 1 137 ? 117.641 126.555 98.624  1.00 122.52 ? 227 GLU B CA  1 
ATOM 1391 C C   . GLU B 1 137 ? 118.511 126.027 99.756  1.00 122.52 ? 227 GLU B C   1 
ATOM 1392 O O   . GLU B 1 137 ? 118.250 126.294 100.933 1.00 122.52 ? 227 GLU B O   1 
ATOM 1393 C CB  . GLU B 1 137 ? 116.568 125.539 98.231  1.00 122.52 ? 227 GLU B CB  1 
ATOM 1394 C CG  . GLU B 1 137 ? 115.306 126.161 97.641  1.00 122.52 ? 227 GLU B CG  1 
ATOM 1395 C CD  . GLU B 1 137 ? 114.415 126.814 98.685  1.00 122.52 ? 227 GLU B CD  1 
ATOM 1396 O OE1 . GLU B 1 137 ? 113.410 127.445 98.299  1.00 122.52 ? 227 GLU B OE1 1 
ATOM 1397 O OE2 . GLU B 1 137 ? 114.717 126.702 99.891  1.00 122.52 ? 227 GLU B OE2 1 
ATOM 1398 N N   . ARG B 1 138 ? 119.564 125.280 99.421  1.00 108.00 ? 228 ARG B N   1 
ATOM 1399 C CA  . ARG B 1 138 ? 120.509 124.877 100.457 1.00 108.00 ? 228 ARG B CA  1 
ATOM 1400 C C   . ARG B 1 138 ? 121.206 126.088 101.063 1.00 108.00 ? 228 ARG B C   1 
ATOM 1401 O O   . ARG B 1 138 ? 121.479 126.123 102.269 1.00 108.00 ? 228 ARG B O   1 
ATOM 1402 C CB  . ARG B 1 138 ? 121.528 123.898 99.881  1.00 108.00 ? 228 ARG B CB  1 
ATOM 1403 C CG  . ARG B 1 138 ? 121.015 122.482 99.759  1.00 108.00 ? 228 ARG B CG  1 
ATOM 1404 C CD  . ARG B 1 138 ? 121.630 121.763 98.574  1.00 108.00 ? 228 ARG B CD  1 
ATOM 1405 N NE  . ARG B 1 138 ? 121.686 120.326 98.808  1.00 108.00 ? 228 ARG B NE  1 
ATOM 1406 C CZ  . ARG B 1 138 ? 122.809 119.653 99.023  1.00 108.00 ? 228 ARG B CZ  1 
ATOM 1407 N NH1 . ARG B 1 138 ? 123.976 120.282 99.016  1.00 108.00 ? 228 ARG B NH1 1 
ATOM 1408 N NH2 . ARG B 1 138 ? 122.765 118.347 99.235  1.00 108.00 ? 228 ARG B NH2 1 
ATOM 1409 N N   . LEU B 1 139 ? 121.525 127.082 100.236 1.00 104.87 ? 229 LEU B N   1 
ATOM 1410 C CA  . LEU B 1 139 ? 122.113 128.299 100.774 1.00 104.87 ? 229 LEU B CA  1 
ATOM 1411 C C   . LEU B 1 139 ? 121.155 128.969 101.740 1.00 104.87 ? 229 LEU B C   1 
ATOM 1412 O O   . LEU B 1 139 ? 121.564 129.458 102.796 1.00 104.87 ? 229 LEU B O   1 
ATOM 1413 C CB  . LEU B 1 139 ? 122.490 129.241 99.640  1.00 104.87 ? 229 LEU B CB  1 
ATOM 1414 C CG  . LEU B 1 139 ? 123.605 128.662 98.785  1.00 104.87 ? 229 LEU B CG  1 
ATOM 1415 C CD1 . LEU B 1 139 ? 123.629 129.352 97.453  1.00 104.87 ? 229 LEU B CD1 1 
ATOM 1416 C CD2 . LEU B 1 139 ? 124.941 128.774 99.475  1.00 104.87 ? 229 LEU B CD2 1 
ATOM 1417 N N   . GLU B 1 140 ? 119.871 128.984 101.401 1.00 117.12 ? 230 GLU B N   1 
ATOM 1418 C CA  . GLU B 1 140 ? 118.890 129.508 102.340 1.00 117.12 ? 230 GLU B CA  1 
ATOM 1419 C C   . GLU B 1 140 ? 118.843 128.672 103.607 1.00 117.12 ? 230 GLU B C   1 
ATOM 1420 O O   . GLU B 1 140 ? 118.626 129.211 104.698 1.00 117.12 ? 230 GLU B O   1 
ATOM 1421 C CB  . GLU B 1 140 ? 117.498 129.558 101.710 1.00 117.12 ? 230 GLU B CB  1 
ATOM 1422 C CG  . GLU B 1 140 ? 116.494 130.333 102.556 1.00 117.12 ? 230 GLU B CG  1 
ATOM 1423 C CD  . GLU B 1 140 ? 115.163 130.533 101.866 1.00 117.12 ? 230 GLU B CD  1 
ATOM 1424 O OE1 . GLU B 1 140 ? 115.004 130.058 100.724 1.00 117.12 ? 230 GLU B OE1 1 
ATOM 1425 O OE2 . GLU B 1 140 ? 114.278 131.177 102.465 1.00 117.12 ? 230 GLU B OE2 1 
ATOM 1426 N N   . ASN B 1 141 ? 118.999 127.360 103.464 1.00 120.57 ? 231 ASN B N   1 
ATOM 1427 C CA  . ASN B 1 141 ? 119.104 126.483 104.621 1.00 120.57 ? 231 ASN B CA  1 
ATOM 1428 C C   . ASN B 1 141 ? 120.222 126.941 105.537 1.00 120.57 ? 231 ASN B C   1 
ATOM 1429 O O   . ASN B 1 141 ? 120.042 127.053 106.755 1.00 120.57 ? 231 ASN B O   1 
ATOM 1430 C CB  . ASN B 1 141 ? 119.349 125.050 104.163 1.00 120.57 ? 231 ASN B CB  1 
ATOM 1431 C CG  . ASN B 1 141 ? 118.114 124.192 104.260 1.00 120.57 ? 231 ASN B CG  1 
ATOM 1432 O OD1 . ASN B 1 141 ? 117.568 123.753 103.245 1.00 120.57 ? 231 ASN B OD1 1 
ATOM 1433 N ND2 . ASN B 1 141 ? 117.658 123.949 105.486 1.00 120.57 ? 231 ASN B ND2 1 
ATOM 1434 N N   . LEU B 1 142 ? 121.386 127.214 104.959 1.00 109.31 ? 232 LEU B N   1 
ATOM 1435 C CA  . LEU B 1 142 ? 122.488 127.747 105.746 1.00 109.31 ? 232 LEU B CA  1 
ATOM 1436 C C   . LEU B 1 142 ? 122.089 129.056 106.408 1.00 109.31 ? 232 LEU B C   1 
ATOM 1437 O O   . LEU B 1 142 ? 122.304 129.251 107.608 1.00 109.31 ? 232 LEU B O   1 
ATOM 1438 C CB  . LEU B 1 142 ? 123.713 127.927 104.861 1.00 109.31 ? 232 LEU B CB  1 
ATOM 1439 C CG  . LEU B 1 142 ? 124.349 126.583 104.523 1.00 109.31 ? 232 LEU B CG  1 
ATOM 1440 C CD1 . LEU B 1 142 ? 125.222 126.739 103.327 1.00 109.31 ? 232 LEU B CD1 1 
ATOM 1441 C CD2 . LEU B 1 142 ? 125.159 126.068 105.688 1.00 109.31 ? 232 LEU B CD2 1 
ATOM 1442 N N   . LEU B 1 143 ? 121.492 129.961 105.634 1.00 113.78 ? 233 LEU B N   1 
ATOM 1443 C CA  . LEU B 1 143 ? 121.113 131.262 106.172 1.00 113.78 ? 233 LEU B CA  1 
ATOM 1444 C C   . LEU B 1 143 ? 120.245 131.135 107.407 1.00 113.78 ? 233 LEU B C   1 
ATOM 1445 O O   . LEU B 1 143 ? 120.603 131.646 108.477 1.00 113.78 ? 233 LEU B O   1 
ATOM 1446 C CB  . LEU B 1 143 ? 120.385 132.081 105.113 1.00 113.78 ? 233 LEU B CB  1 
ATOM 1447 C CG  . LEU B 1 143 ? 121.258 132.756 104.056 1.00 113.78 ? 233 LEU B CG  1 
ATOM 1448 C CD1 . LEU B 1 143 ? 120.816 134.197 103.914 1.00 113.78 ? 233 LEU B CD1 1 
ATOM 1449 C CD2 . LEU B 1 143 ? 122.730 132.691 104.406 1.00 113.78 ? 233 LEU B CD2 1 
ATOM 1450 N N   . ASN B 1 144 ? 119.114 130.445 107.299 1.00 121.84 ? 234 ASN B N   1 
ATOM 1451 C CA  . ASN B 1 144 ? 118.215 130.439 108.444 1.00 121.84 ? 234 ASN B CA  1 
ATOM 1452 C C   . ASN B 1 144 ? 118.795 129.616 109.585 1.00 121.84 ? 234 ASN B C   1 
ATOM 1453 O O   . ASN B 1 144 ? 118.619 129.977 110.755 1.00 121.84 ? 234 ASN B O   1 
ATOM 1454 C CB  . ASN B 1 144 ? 116.809 129.947 108.077 1.00 121.84 ? 234 ASN B CB  1 
ATOM 1455 C CG  . ASN B 1 144 ? 116.813 128.660 107.295 1.00 121.84 ? 234 ASN B CG  1 
ATOM 1456 O OD1 . ASN B 1 144 ? 117.858 128.132 106.967 1.00 121.84 ? 234 ASN B OD1 1 
ATOM 1457 N ND2 . ASN B 1 144 ? 115.628 128.146 106.995 1.00 121.84 ? 234 ASN B ND2 1 
ATOM 1458 N N   . ILE B 1 145 ? 119.506 128.523 109.284 1.00 110.97 ? 235 ILE B N   1 
ATOM 1459 C CA  . ILE B 1 145 ? 120.026 127.723 110.384 1.00 110.97 ? 235 ILE B CA  1 
ATOM 1460 C C   . ILE B 1 145 ? 121.029 128.531 111.188 1.00 110.97 ? 235 ILE B C   1 
ATOM 1461 O O   . ILE B 1 145 ? 120.996 128.534 112.427 1.00 110.97 ? 235 ILE B O   1 
ATOM 1462 C CB  . ILE B 1 145 ? 120.611 126.393 109.876 1.00 110.97 ? 235 ILE B CB  1 
ATOM 1463 C CG1 . ILE B 1 145 ? 120.754 125.419 111.043 1.00 110.97 ? 235 ILE B CG1 1 
ATOM 1464 C CG2 . ILE B 1 145 ? 121.955 126.583 109.203 1.00 110.97 ? 235 ILE B CG2 1 
ATOM 1465 C CD1 . ILE B 1 145 ? 121.039 124.005 110.625 1.00 110.97 ? 235 ILE B CD1 1 
ATOM 1466 N N   . VAL B 1 146 ? 121.888 129.289 110.512 1.00 104.84 ? 236 VAL B N   1 
ATOM 1467 C CA  . VAL B 1 146 ? 122.857 130.071 111.258 1.00 104.84 ? 236 VAL B CA  1 
ATOM 1468 C C   . VAL B 1 146 ? 122.173 131.248 111.935 1.00 104.84 ? 236 VAL B C   1 
ATOM 1469 O O   . VAL B 1 146 ? 122.625 131.722 112.983 1.00 104.84 ? 236 VAL B O   1 
ATOM 1470 C CB  . VAL B 1 146 ? 124.014 130.502 110.347 1.00 104.84 ? 236 VAL B CB  1 
ATOM 1471 C CG1 . VAL B 1 146 ? 124.597 129.283 109.675 1.00 104.84 ? 236 VAL B CG1 1 
ATOM 1472 C CG2 . VAL B 1 146 ? 123.534 131.483 109.323 1.00 104.84 ? 236 VAL B CG2 1 
ATOM 1473 N N   . ARG B 1 147 ? 121.057 131.720 111.377 1.00 113.00 ? 237 ARG B N   1 
ATOM 1474 C CA  . ARG B 1 147 ? 120.282 132.714 112.111 1.00 113.00 ? 237 ARG B CA  1 
ATOM 1475 C C   . ARG B 1 147 ? 119.822 132.162 113.451 1.00 113.00 ? 237 ARG B C   1 
ATOM 1476 O O   . ARG B 1 147 ? 120.016 132.802 114.497 1.00 113.00 ? 237 ARG B O   1 
ATOM 1477 C CB  . ARG B 1 147 ? 119.078 133.176 111.297 1.00 113.00 ? 237 ARG B CB  1 
ATOM 1478 C CG  . ARG B 1 147 ? 119.330 134.386 110.440 1.00 113.00 ? 237 ARG B CG  1 
ATOM 1479 C CD  . ARG B 1 147 ? 118.058 134.763 109.732 1.00 113.00 ? 237 ARG B CD  1 
ATOM 1480 N NE  . ARG B 1 147 ? 118.295 135.776 108.720 1.00 113.00 ? 237 ARG B NE  1 
ATOM 1481 C CZ  . ARG B 1 147 ? 118.004 135.616 107.436 1.00 113.00 ? 237 ARG B CZ  1 
ATOM 1482 N NH1 . ARG B 1 147 ? 117.464 134.481 107.015 1.00 113.00 ? 237 ARG B NH1 1 
ATOM 1483 N NH2 . ARG B 1 147 ? 118.257 136.591 106.576 1.00 113.00 ? 237 ARG B NH2 1 
ATOM 1484 N N   . GLU B 1 148 ? 119.193 130.986 113.438 1.00 110.59 ? 238 GLU B N   1 
ATOM 1485 C CA  . GLU B 1 148 ? 118.761 130.398 114.697 1.00 110.59 ? 238 GLU B CA  1 
ATOM 1486 C C   . GLU B 1 148 ? 119.934 130.198 115.632 1.00 110.59 ? 238 GLU B C   1 
ATOM 1487 O O   . GLU B 1 148 ? 119.800 130.389 116.843 1.00 110.59 ? 238 GLU B O   1 
ATOM 1488 C CB  . GLU B 1 148 ? 118.039 129.067 114.495 1.00 110.59 ? 238 GLU B CB  1 
ATOM 1489 C CG  . GLU B 1 148 ? 116.661 129.176 113.878 1.00 110.59 ? 238 GLU B CG  1 
ATOM 1490 C CD  . GLU B 1 148 ? 116.625 128.741 112.436 1.00 110.59 ? 238 GLU B CD  1 
ATOM 1491 O OE1 . GLU B 1 148 ? 117.549 128.019 112.025 1.00 110.59 ? 238 GLU B OE1 1 
ATOM 1492 O OE2 . GLU B 1 148 ? 115.677 129.117 111.712 1.00 110.59 ? 238 GLU B OE2 1 
ATOM 1493 N N   . ILE B 1 149 ? 121.083 129.802 115.095 1.00 95.82  ? 239 ILE B N   1 
ATOM 1494 C CA  . ILE B 1 149 ? 122.244 129.605 115.953 1.00 95.82  ? 239 ILE B CA  1 
ATOM 1495 C C   . ILE B 1 149 ? 122.641 130.917 116.611 1.00 95.82  ? 239 ILE B C   1 
ATOM 1496 O O   . ILE B 1 149 ? 122.936 130.965 117.811 1.00 95.82  ? 239 ILE B O   1 
ATOM 1497 C CB  . ILE B 1 149 ? 123.405 128.995 115.157 1.00 95.82  ? 239 ILE B CB  1 
ATOM 1498 C CG1 . ILE B 1 149 ? 123.095 127.542 114.840 1.00 95.82  ? 239 ILE B CG1 1 
ATOM 1499 C CG2 . ILE B 1 149 ? 124.670 129.059 115.965 1.00 95.82  ? 239 ILE B CG2 1 
ATOM 1500 C CD1 . ILE B 1 149 ? 124.266 126.797 114.305 1.00 95.82  ? 239 ILE B CD1 1 
ATOM 1501 N N   . LEU B 1 150 ? 122.658 132.000 115.836 1.00 94.54  ? 240 LEU B N   1 
ATOM 1502 C CA  . LEU B 1 150 ? 123.003 133.290 116.414 1.00 94.54  ? 240 LEU B CA  1 
ATOM 1503 C C   . LEU B 1 150 ? 122.034 133.667 117.516 1.00 94.54  ? 240 LEU B C   1 
ATOM 1504 O O   . LEU B 1 150 ? 122.451 134.155 118.574 1.00 94.54  ? 240 LEU B O   1 
ATOM 1505 C CB  . LEU B 1 150 ? 123.027 134.372 115.337 1.00 94.54  ? 240 LEU B CB  1 
ATOM 1506 C CG  . LEU B 1 150 ? 123.493 135.764 115.777 1.00 94.54  ? 240 LEU B CG  1 
ATOM 1507 C CD1 . LEU B 1 150 ? 124.315 136.429 114.690 1.00 94.54  ? 240 LEU B CD1 1 
ATOM 1508 C CD2 . LEU B 1 150 ? 122.310 136.646 116.127 1.00 94.54  ? 240 LEU B CD2 1 
ATOM 1509 N N   . ASP B 1 151 ? 120.743 133.438 117.296 1.00 105.33 ? 241 ASP B N   1 
ATOM 1510 C CA  . ASP B 1 151 ? 119.766 133.780 118.324 1.00 105.33 ? 241 ASP B CA  1 
ATOM 1511 C C   . ASP B 1 151 ? 119.968 132.929 119.573 1.00 105.33 ? 241 ASP B C   1 
ATOM 1512 O O   . ASP B 1 151 ? 119.896 133.430 120.705 1.00 105.33 ? 241 ASP B O   1 
ATOM 1513 C CB  . ASP B 1 151 ? 118.350 133.613 117.778 1.00 105.33 ? 241 ASP B CB  1 
ATOM 1514 C CG  . ASP B 1 151 ? 117.307 134.236 118.678 1.00 105.33 ? 241 ASP B CG  1 
ATOM 1515 O OD1 . ASP B 1 151 ? 117.604 135.281 119.291 1.00 105.33 ? 241 ASP B OD1 1 
ATOM 1516 O OD2 . ASP B 1 151 ? 116.191 133.684 118.771 1.00 105.33 ? 241 ASP B OD2 1 
ATOM 1517 N N   . VAL B 1 152 ? 120.217 131.633 119.382 1.00 94.64  ? 242 VAL B N   1 
ATOM 1518 C CA  . VAL B 1 152 ? 120.418 130.735 120.511 1.00 94.64  ? 242 VAL B CA  1 
ATOM 1519 C C   . VAL B 1 152 ? 121.634 131.161 121.311 1.00 94.64  ? 242 VAL B C   1 
ATOM 1520 O O   . VAL B 1 152 ? 121.631 131.118 122.545 1.00 94.64  ? 242 VAL B O   1 
ATOM 1521 C CB  . VAL B 1 152 ? 120.535 129.283 120.017 1.00 94.64  ? 242 VAL B CB  1 
ATOM 1522 C CG1 . VAL B 1 152 ? 121.202 128.424 121.059 1.00 94.64  ? 242 VAL B CG1 1 
ATOM 1523 C CG2 . VAL B 1 152 ? 119.163 128.734 119.701 1.00 94.64  ? 242 VAL B CG2 1 
ATOM 1524 N N   . GLN B 1 153 ? 122.686 131.606 120.629 1.00 92.20  ? 243 GLN B N   1 
ATOM 1525 C CA  . GLN B 1 153 ? 123.874 132.046 121.343 1.00 92.20  ? 243 GLN B CA  1 
ATOM 1526 C C   . GLN B 1 153 ? 123.619 133.349 122.080 1.00 92.20  ? 243 GLN B C   1 
ATOM 1527 O O   . GLN B 1 153 ? 124.099 133.540 123.203 1.00 92.20  ? 243 GLN B O   1 
ATOM 1528 C CB  . GLN B 1 153 ? 125.043 132.186 120.376 1.00 92.20  ? 243 GLN B CB  1 
ATOM 1529 C CG  . GLN B 1 153 ? 125.556 130.854 119.886 1.00 92.20  ? 243 GLN B CG  1 
ATOM 1530 C CD  . GLN B 1 153 ? 125.409 129.768 120.929 1.00 92.20  ? 243 GLN B CD  1 
ATOM 1531 O OE1 . GLN B 1 153 ? 124.425 129.028 120.944 1.00 92.20  ? 243 GLN B OE1 1 
ATOM 1532 N NE2 . GLN B 1 153 ? 126.379 129.684 121.822 1.00 92.20  ? 243 GLN B NE2 1 
ATOM 1533 N N   . ARG B 1 154 ? 122.875 134.262 121.461 1.00 98.88  ? 244 ARG B N   1 
ATOM 1534 C CA  . ARG B 1 154 ? 122.431 135.449 122.177 1.00 98.88  ? 244 ARG B CA  1 
ATOM 1535 C C   . ARG B 1 154 ? 121.762 135.074 123.491 1.00 98.88  ? 244 ARG B C   1 
ATOM 1536 O O   . ARG B 1 154 ? 122.153 135.552 124.569 1.00 98.88  ? 244 ARG B O   1 
ATOM 1537 C CB  . ARG B 1 154 ? 121.470 136.247 121.301 1.00 98.88  ? 244 ARG B CB  1 
ATOM 1538 C CG  . ARG B 1 154 ? 120.621 137.238 122.064 1.00 98.88  ? 244 ARG B CG  1 
ATOM 1539 C CD  . ARG B 1 154 ? 119.667 137.977 121.139 1.00 98.88  ? 244 ARG B CD  1 
ATOM 1540 N NE  . ARG B 1 154 ? 120.364 138.683 120.068 1.00 98.88  ? 244 ARG B NE  1 
ATOM 1541 C CZ  . ARG B 1 154 ? 120.370 138.298 118.796 1.00 98.88  ? 244 ARG B CZ  1 
ATOM 1542 N NH1 . ARG B 1 154 ? 119.717 137.204 118.427 1.00 98.88  ? 244 ARG B NH1 1 
ATOM 1543 N NH2 . ARG B 1 154 ? 121.032 139.008 117.893 1.00 98.88  ? 244 ARG B NH2 1 
ATOM 1544 N N   . ASP B 1 155 ? 120.764 134.200 123.424 1.00 96.40  ? 245 ASP B N   1 
ATOM 1545 C CA  . ASP B 1 155 ? 120.015 133.850 124.619 1.00 96.40  ? 245 ASP B CA  1 
ATOM 1546 C C   . ASP B 1 155 ? 120.848 133.080 125.636 1.00 96.40  ? 245 ASP B C   1 
ATOM 1547 O O   . ASP B 1 155 ? 120.668 133.278 126.843 1.00 96.40  ? 245 ASP B O   1 
ATOM 1548 C CB  . ASP B 1 155 ? 118.773 133.043 124.248 1.00 96.40  ? 245 ASP B CB  1 
ATOM 1549 C CG  . ASP B 1 155 ? 117.714 133.099 125.320 1.00 96.40  ? 245 ASP B CG  1 
ATOM 1550 O OD1 . ASP B 1 155 ? 117.004 134.123 125.399 1.00 96.40  ? 245 ASP B OD1 1 
ATOM 1551 O OD2 . ASP B 1 155 ? 117.603 132.132 126.097 1.00 96.40  ? 245 ASP B OD2 1 
ATOM 1552 N N   . MET B 1 156 ? 121.762 132.225 125.187 1.00 85.18  ? 246 MET B N   1 
ATOM 1553 C CA  . MET B 1 156 ? 122.678 131.597 126.127 1.00 85.18  ? 246 MET B CA  1 
ATOM 1554 C C   . MET B 1 156 ? 123.530 132.634 126.827 1.00 85.18  ? 246 MET B C   1 
ATOM 1555 O O   . MET B 1 156 ? 123.778 132.527 128.030 1.00 85.18  ? 246 MET B O   1 
ATOM 1556 C CB  . MET B 1 156 ? 123.573 130.582 125.425 1.00 85.18  ? 246 MET B CB  1 
ATOM 1557 C CG  . MET B 1 156 ? 122.955 129.221 125.253 1.00 85.18  ? 246 MET B CG  1 
ATOM 1558 S SD  . MET B 1 156 ? 124.199 128.028 124.744 1.00 85.18  ? 246 MET B SD  1 
ATOM 1559 C CE  . MET B 1 156 ? 125.192 127.939 126.229 1.00 85.18  ? 246 MET B CE  1 
ATOM 1560 N N   . ARG B 1 157 ? 124.027 133.622 126.088 1.00 81.53  ? 247 ARG B N   1 
ATOM 1561 C CA  . ARG B 1 157 ? 124.806 134.663 126.733 1.00 81.53  ? 247 ARG B CA  1 
ATOM 1562 C C   . ARG B 1 157 ? 123.988 135.351 127.810 1.00 81.53  ? 247 ARG B C   1 
ATOM 1563 O O   . ARG B 1 157 ? 124.492 135.624 128.908 1.00 81.53  ? 247 ARG B O   1 
ATOM 1564 C CB  . ARG B 1 157 ? 125.294 135.679 125.714 1.00 81.53  ? 247 ARG B CB  1 
ATOM 1565 C CG  . ARG B 1 157 ? 125.443 137.046 126.320 1.00 81.53  ? 247 ARG B CG  1 
ATOM 1566 C CD  . ARG B 1 157 ? 126.202 137.968 125.422 1.00 81.53  ? 247 ARG B CD  1 
ATOM 1567 N NE  . ARG B 1 157 ? 127.632 137.873 125.660 1.00 81.53  ? 247 ARG B NE  1 
ATOM 1568 C CZ  . ARG B 1 157 ? 128.505 138.800 125.287 1.00 81.53  ? 247 ARG B CZ  1 
ATOM 1569 N NH1 . ARG B 1 157 ? 128.091 139.891 124.657 1.00 81.53  ? 247 ARG B NH1 1 
ATOM 1570 N NH2 . ARG B 1 157 ? 129.789 138.636 125.540 1.00 81.53  ? 247 ARG B NH2 1 
ATOM 1571 N N   . ASN B 1 158 ? 122.722 135.636 127.515 1.00 85.29  ? 248 ASN B N   1 
ATOM 1572 C CA  . ASN B 1 158 ? 121.864 136.241 128.530 1.00 85.29  ? 248 ASN B CA  1 
ATOM 1573 C C   . ASN B 1 158 ? 121.725 135.324 129.740 1.00 85.29  ? 248 ASN B C   1 
ATOM 1574 O O   . ASN B 1 158 ? 121.799 135.770 130.894 1.00 85.29  ? 248 ASN B O   1 
ATOM 1575 C CB  . ASN B 1 158 ? 120.499 136.569 127.935 1.00 85.29  ? 248 ASN B CB  1 
ATOM 1576 C CG  . ASN B 1 158 ? 120.539 137.789 127.047 1.00 85.29  ? 248 ASN B CG  1 
ATOM 1577 O OD1 . ASN B 1 158 ? 121.308 138.717 127.290 1.00 85.29  ? 248 ASN B OD1 1 
ATOM 1578 N ND2 . ASN B 1 158 ? 119.712 137.796 126.009 1.00 85.29  ? 248 ASN B ND2 1 
ATOM 1579 N N   . ASP B 1 159 ? 121.540 134.032 129.491 1.00 73.95  ? 249 ASP B N   1 
ATOM 1580 C CA  . ASP B 1 159 ? 121.420 133.076 130.581 1.00 73.95  ? 249 ASP B CA  1 
ATOM 1581 C C   . ASP B 1 159 ? 122.674 133.059 131.445 1.00 73.95  ? 249 ASP B C   1 
ATOM 1582 O O   . ASP B 1 159 ? 122.589 133.015 132.677 1.00 73.95  ? 249 ASP B O   1 
ATOM 1583 C CB  . ASP B 1 159 ? 121.141 131.693 130.002 1.00 73.95  ? 249 ASP B CB  1 
ATOM 1584 C CG  . ASP B 1 159 ? 120.517 130.756 131.003 1.00 73.95  ? 249 ASP B CG  1 
ATOM 1585 O OD1 . ASP B 1 159 ? 119.346 130.981 131.365 1.00 73.95  ? 249 ASP B OD1 1 
ATOM 1586 O OD2 . ASP B 1 159 ? 121.179 129.782 131.411 1.00 73.95  ? 249 ASP B OD2 1 
ATOM 1587 N N   . LEU B 1 160 ? 123.841 133.119 130.815 1.00 64.12  ? 250 LEU B N   1 
ATOM 1588 C CA  . LEU B 1 160 ? 125.087 133.063 131.565 1.00 64.12  ? 250 LEU B CA  1 
ATOM 1589 C C   . LEU B 1 160 ? 125.282 134.323 132.389 1.00 64.12  ? 250 LEU B C   1 
ATOM 1590 O O   . LEU B 1 160 ? 125.747 134.258 133.531 1.00 64.12  ? 250 LEU B O   1 
ATOM 1591 C CB  . LEU B 1 160 ? 126.258 132.859 130.616 1.00 64.12  ? 250 LEU B CB  1 
ATOM 1592 C CG  . LEU B 1 160 ? 127.399 132.108 131.270 1.00 64.12  ? 250 LEU B CG  1 
ATOM 1593 C CD1 . LEU B 1 160 ? 126.878 130.783 131.743 1.00 64.12  ? 250 LEU B CD1 1 
ATOM 1594 C CD2 . LEU B 1 160 ? 128.505 131.904 130.283 1.00 64.12  ? 250 LEU B CD2 1 
ATOM 1595 N N   . SER B 1 161 ? 124.956 135.481 131.819 1.00 73.69  ? 251 SER B N   1 
ATOM 1596 C CA  . SER B 1 161 ? 124.932 136.694 132.625 1.00 73.69  ? 251 SER B CA  1 
ATOM 1597 C C   . SER B 1 161 ? 124.046 136.520 133.846 1.00 73.69  ? 251 SER B C   1 
ATOM 1598 O O   . SER B 1 161 ? 124.434 136.903 134.963 1.00 73.69  ? 251 SER B O   1 
ATOM 1599 C CB  . SER B 1 161 ? 124.438 137.873 131.791 1.00 73.69  ? 251 SER B CB  1 
ATOM 1600 O OG  . SER B 1 161 ? 124.292 139.034 132.589 1.00 73.69  ? 251 SER B OG  1 
ATOM 1601 N N   . ASN B 1 162 ? 122.860 135.951 133.647 1.00 65.35  ? 252 ASN B N   1 
ATOM 1602 C CA  . ASN B 1 162 ? 121.975 135.687 134.771 1.00 65.35  ? 252 ASN B CA  1 
ATOM 1603 C C   . ASN B 1 162 ? 122.690 134.856 135.827 1.00 65.35  ? 252 ASN B C   1 
ATOM 1604 O O   . ASN B 1 162 ? 122.677 135.188 137.022 1.00 65.35  ? 252 ASN B O   1 
ATOM 1605 C CB  . ASN B 1 162 ? 120.719 134.975 134.276 1.00 65.35  ? 252 ASN B CB  1 
ATOM 1606 C CG  . ASN B 1 162 ? 119.481 135.378 135.041 1.00 65.35  ? 252 ASN B CG  1 
ATOM 1607 O OD1 . ASN B 1 162 ? 119.494 136.351 135.789 1.00 65.35  ? 252 ASN B OD1 1 
ATOM 1608 N ND2 . ASN B 1 162 ? 118.404 134.622 134.868 1.00 65.35  ? 252 ASN B ND2 1 
ATOM 1609 N N   . LEU B 1 163 ? 123.347 133.783 135.397 1.00 55.15  ? 253 LEU B N   1 
ATOM 1610 C CA  . LEU B 1 163 ? 123.962 132.885 136.363 1.00 55.15  ? 253 LEU B CA  1 
ATOM 1611 C C   . LEU B 1 163 ? 125.092 133.586 137.106 1.00 55.15  ? 253 LEU B C   1 
ATOM 1612 O O   . LEU B 1 163 ? 125.305 133.347 138.300 1.00 55.15  ? 253 LEU B O   1 
ATOM 1613 C CB  . LEU B 1 163 ? 124.475 131.629 135.671 1.00 55.15  ? 253 LEU B CB  1 
ATOM 1614 C CG  . LEU B 1 163 ? 124.752 130.470 136.624 1.00 55.15  ? 253 LEU B CG  1 
ATOM 1615 C CD1 . LEU B 1 163 ? 123.438 129.918 137.126 1.00 55.15  ? 253 LEU B CD1 1 
ATOM 1616 C CD2 . LEU B 1 163 ? 125.545 129.388 135.970 1.00 55.15  ? 253 LEU B CD2 1 
ATOM 1617 N N   . THR B 1 164 ? 125.826 134.459 136.415 1.00 53.35  ? 254 THR B N   1 
ATOM 1618 C CA  . THR B 1 164 ? 126.913 135.180 137.069 1.00 53.35  ? 254 THR B CA  1 
ATOM 1619 C C   . THR B 1 164 ? 126.376 136.077 138.166 1.00 53.35  ? 254 THR B C   1 
ATOM 1620 O O   . THR B 1 164 ? 126.874 136.065 139.303 1.00 53.35  ? 254 THR B O   1 
ATOM 1621 C CB  . THR B 1 164 ? 127.690 136.010 136.059 1.00 53.35  ? 254 THR B CB  1 
ATOM 1622 O OG1 . THR B 1 164 ? 128.109 135.171 134.986 1.00 53.35  ? 254 THR B OG1 1 
ATOM 1623 C CG2 . THR B 1 164 ? 128.907 136.602 136.712 1.00 53.35  ? 254 THR B CG2 1 
ATOM 1624 N N   . ARG B 1 165 ? 125.376 136.890 137.831 1.00 60.77  ? 255 ARG B N   1 
ATOM 1625 C CA  . ARG B 1 165 ? 124.749 137.684 138.874 1.00 60.77  ? 255 ARG B CA  1 
ATOM 1626 C C   . ARG B 1 165 ? 124.330 136.822 140.045 1.00 60.77  ? 255 ARG B C   1 
ATOM 1627 O O   . ARG B 1 165 ? 124.600 137.190 141.194 1.00 60.77  ? 255 ARG B O   1 
ATOM 1628 C CB  . ARG B 1 165 ? 123.533 138.435 138.349 1.00 60.77  ? 255 ARG B CB  1 
ATOM 1629 C CG  . ARG B 1 165 ? 123.862 139.649 137.520 1.00 60.77  ? 255 ARG B CG  1 
ATOM 1630 C CD  . ARG B 1 165 ? 122.604 140.446 137.219 1.00 60.77  ? 255 ARG B CD  1 
ATOM 1631 N NE  . ARG B 1 165 ? 121.600 139.638 136.534 1.00 60.77  ? 255 ARG B NE  1 
ATOM 1632 C CZ  . ARG B 1 165 ? 121.574 139.430 135.222 1.00 60.77  ? 255 ARG B CZ  1 
ATOM 1633 N NH1 . ARG B 1 165 ? 122.499 139.969 134.442 1.00 60.77  ? 255 ARG B NH1 1 
ATOM 1634 N NH2 . ARG B 1 165 ? 120.623 138.676 134.692 1.00 60.77  ? 255 ARG B NH2 1 
ATOM 1635 N N   . LYS B 1 166 ? 123.710 135.672 139.784 1.00 50.51  ? 256 LYS B N   1 
ATOM 1636 C CA  . LYS B 1 166 ? 123.196 134.886 140.898 1.00 50.51  ? 256 LYS B CA  1 
ATOM 1637 C C   . LYS B 1 166 ? 124.313 134.335 141.776 1.00 50.51  ? 256 LYS B C   1 
ATOM 1638 O O   . LYS B 1 166 ? 124.205 134.350 143.011 1.00 50.51  ? 256 LYS B O   1 
ATOM 1639 C CB  . LYS B 1 166 ? 122.314 133.759 140.392 1.00 50.51  ? 256 LYS B CB  1 
ATOM 1640 C CG  . LYS B 1 166 ? 120.886 133.960 140.777 1.00 50.51  ? 256 LYS B CG  1 
ATOM 1641 C CD  . LYS B 1 166 ? 120.031 132.873 140.215 1.00 50.51  ? 256 LYS B CD  1 
ATOM 1642 C CE  . LYS B 1 166 ? 118.574 133.250 140.306 1.00 50.51  ? 256 LYS B CE  1 
ATOM 1643 N NZ  . LYS B 1 166 ? 117.712 132.258 139.613 1.00 50.51  ? 256 LYS B NZ  1 
ATOM 1644 N N   . VAL B 1 167 ? 125.397 133.856 141.171 1.00 41.17  ? 257 VAL B N   1 
ATOM 1645 C CA  . VAL B 1 167 ? 126.478 133.318 141.986 1.00 41.17  ? 257 VAL B CA  1 
ATOM 1646 C C   . VAL B 1 167 ? 127.087 134.416 142.841 1.00 41.17  ? 257 VAL B C   1 
ATOM 1647 O O   . VAL B 1 167 ? 127.342 134.222 144.038 1.00 41.17  ? 257 VAL B O   1 
ATOM 1648 C CB  . VAL B 1 167 ? 127.530 132.629 141.109 1.00 41.17  ? 257 VAL B CB  1 
ATOM 1649 C CG1 . VAL B 1 167 ? 128.823 132.516 141.859 1.00 41.17  ? 257 VAL B CG1 1 
ATOM 1650 C CG2 . VAL B 1 167 ? 127.050 131.264 140.728 1.00 41.17  ? 257 VAL B CG2 1 
ATOM 1651 N N   . ASP B 1 168 ? 127.308 135.594 142.262 1.00 45.84  ? 258 ASP B N   1 
ATOM 1652 C CA  . ASP B 1 168 ? 127.881 136.662 143.069 1.00 45.84  ? 258 ASP B CA  1 
ATOM 1653 C C   . ASP B 1 168 ? 126.966 137.035 144.221 1.00 45.84  ? 258 ASP B C   1 
ATOM 1654 O O   . ASP B 1 168 ? 127.424 137.229 145.357 1.00 45.84  ? 258 ASP B O   1 
ATOM 1655 C CB  . ASP B 1 168 ? 128.171 137.875 142.205 1.00 45.84  ? 258 ASP B CB  1 
ATOM 1656 C CG  . ASP B 1 168 ? 129.619 137.971 141.846 1.00 45.84  ? 258 ASP B CG  1 
ATOM 1657 O OD1 . ASP B 1 168 ? 130.376 137.099 142.307 1.00 45.84  ? 258 ASP B OD1 1 
ATOM 1658 O OD2 . ASP B 1 168 ? 130.004 138.909 141.120 1.00 45.84  ? 258 ASP B OD2 1 
ATOM 1659 N N   . ARG B 1 169 ? 125.675 137.176 143.937 1.00 48.37  ? 259 ARG B N   1 
ATOM 1660 C CA  . ARG B 1 169 ? 124.706 137.413 144.995 1.00 48.37  ? 259 ARG B CA  1 
ATOM 1661 C C   . ARG B 1 169 ? 124.905 136.440 146.146 1.00 48.37  ? 259 ARG B C   1 
ATOM 1662 O O   . ARG B 1 169 ? 125.123 136.852 147.294 1.00 48.37  ? 259 ARG B O   1 
ATOM 1663 C CB  . ARG B 1 169 ? 123.298 137.278 144.433 1.00 48.37  ? 259 ARG B CB  1 
ATOM 1664 C CG  . ARG B 1 169 ? 122.235 137.177 145.475 1.00 48.37  ? 259 ARG B CG  1 
ATOM 1665 C CD  . ARG B 1 169 ? 121.912 138.542 145.927 1.00 48.37  ? 259 ARG B CD  1 
ATOM 1666 N NE  . ARG B 1 169 ? 121.289 139.278 144.847 1.00 48.37  ? 259 ARG B NE  1 
ATOM 1667 C CZ  . ARG B 1 169 ? 121.193 140.597 144.818 1.00 48.37  ? 259 ARG B CZ  1 
ATOM 1668 N NH1 . ARG B 1 169 ? 121.695 141.312 145.810 1.00 48.37  ? 259 ARG B NH1 1 
ATOM 1669 N NH2 . ARG B 1 169 ? 120.605 141.199 143.799 1.00 48.37  ? 259 ARG B NH2 1 
ATOM 1670 N N   . MET B 1 170 ? 124.852 135.145 145.851 1.00 42.73  ? 260 MET B N   1 
ATOM 1671 C CA  . MET B 1 170 ? 124.954 134.162 146.922 1.00 42.73  ? 260 MET B CA  1 
ATOM 1672 C C   . MET B 1 170 ? 126.267 134.313 147.674 1.00 42.73  ? 260 MET B C   1 
ATOM 1673 O O   . MET B 1 170 ? 126.328 134.100 148.892 1.00 42.73  ? 260 MET B O   1 
ATOM 1674 C CB  . MET B 1 170 ? 124.810 132.755 146.351 1.00 42.73  ? 260 MET B CB  1 
ATOM 1675 C CG  . MET B 1 170 ? 124.790 131.682 147.399 1.00 42.73  ? 260 MET B CG  1 
ATOM 1676 S SD  . MET B 1 170 ? 124.697 130.079 146.628 1.00 42.73  ? 260 MET B SD  1 
ATOM 1677 C CE  . MET B 1 170 ? 126.197 130.162 145.677 1.00 42.73  ? 260 MET B CE  1 
ATOM 1678 N N   . ASP B 1 171 ? 127.332 134.676 146.962 1.00 44.24  ? 261 ASP B N   1 
ATOM 1679 C CA  . ASP B 1 171 ? 128.611 134.875 147.630 1.00 44.24  ? 261 ASP B CA  1 
ATOM 1680 C C   . ASP B 1 171 ? 128.491 135.935 148.707 1.00 44.24  ? 261 ASP B C   1 
ATOM 1681 O O   . ASP B 1 171 ? 128.896 135.721 149.860 1.00 44.24  ? 261 ASP B O   1 
ATOM 1682 C CB  . ASP B 1 171 ? 129.673 135.275 146.613 1.00 44.24  ? 261 ASP B CB  1 
ATOM 1683 C CG  . ASP B 1 171 ? 131.060 135.295 147.203 1.00 44.24  ? 261 ASP B CG  1 
ATOM 1684 O OD1 . ASP B 1 171 ? 131.204 134.937 148.384 1.00 44.24  ? 261 ASP B OD1 1 
ATOM 1685 O OD2 . ASP B 1 171 ? 132.011 135.663 146.487 1.00 44.24  ? 261 ASP B OD2 1 
ATOM 1686 N N   . MET B 1 172 ? 127.957 137.092 148.335 1.00 43.58  ? 262 MET B N   1 
ATOM 1687 C CA  . MET B 1 172 ? 127.745 138.138 149.324 1.00 43.58  ? 262 MET B CA  1 
ATOM 1688 C C   . MET B 1 172 ? 126.943 137.601 150.495 1.00 43.58  ? 262 MET B C   1 
ATOM 1689 O O   . MET B 1 172 ? 127.283 137.838 151.662 1.00 43.58  ? 262 MET B O   1 
ATOM 1690 C CB  . MET B 1 172 ? 127.035 139.331 148.697 1.00 43.58  ? 262 MET B CB  1 
ATOM 1691 C CG  . MET B 1 172 ? 126.872 140.499 149.630 1.00 43.58  ? 262 MET B CG  1 
ATOM 1692 S SD  . MET B 1 172 ? 125.365 140.433 150.608 1.00 43.58  ? 262 MET B SD  1 
ATOM 1693 C CE  . MET B 1 172 ? 124.193 141.101 149.450 1.00 43.58  ? 262 MET B CE  1 
ATOM 1694 N N   . ARG B 1 173 ? 125.876 136.854 150.196 1.00 47.14  ? 263 ARG B N   1 
ATOM 1695 C CA  . ARG B 1 173 ? 124.982 136.397 151.257 1.00 47.14  ? 263 ARG B CA  1 
ATOM 1696 C C   . ARG B 1 173 ? 125.725 135.545 152.273 1.00 47.14  ? 263 ARG B C   1 
ATOM 1697 O O   . ARG B 1 173 ? 125.619 135.765 153.487 1.00 47.14  ? 263 ARG B O   1 
ATOM 1698 C CB  . ARG B 1 173 ? 123.807 135.609 150.682 1.00 47.14  ? 263 ARG B CB  1 
ATOM 1699 C CG  . ARG B 1 173 ? 122.823 135.188 151.757 1.00 47.14  ? 263 ARG B CG  1 
ATOM 1700 C CD  . ARG B 1 173 ? 121.728 134.302 151.231 1.00 47.14  ? 263 ARG B CD  1 
ATOM 1701 N NE  . ARG B 1 173 ? 121.191 134.788 149.971 1.00 47.14  ? 263 ARG B NE  1 
ATOM 1702 C CZ  . ARG B 1 173 ? 120.249 135.714 149.879 1.00 47.14  ? 263 ARG B CZ  1 
ATOM 1703 N NH1 . ARG B 1 173 ? 119.748 136.256 150.975 1.00 47.14  ? 263 ARG B NH1 1 
ATOM 1704 N NH2 . ARG B 1 173 ? 119.811 136.097 148.692 1.00 47.14  ? 263 ARG B NH2 1 
ATOM 1705 N N   . LEU B 1 174 ? 126.480 134.565 151.793 1.00 46.99  ? 264 LEU B N   1 
ATOM 1706 C CA  . LEU B 1 174 ? 127.124 133.664 152.738 1.00 46.99  ? 264 LEU B CA  1 
ATOM 1707 C C   . LEU B 1 174 ? 128.232 134.358 153.506 1.00 46.99  ? 264 LEU B C   1 
ATOM 1708 O O   . LEU B 1 174 ? 128.375 134.136 154.714 1.00 46.99  ? 264 LEU B O   1 
ATOM 1709 C CB  . LEU B 1 174 ? 127.654 132.424 152.037 1.00 46.99  ? 264 LEU B CB  1 
ATOM 1710 C CG  . LEU B 1 174 ? 126.597 131.354 152.284 1.00 46.99  ? 264 LEU B CG  1 
ATOM 1711 C CD1 . LEU B 1 174 ? 126.412 130.434 151.096 1.00 46.99  ? 264 LEU B CD1 1 
ATOM 1712 C CD2 . LEU B 1 174 ? 126.923 130.587 153.542 1.00 46.99  ? 264 LEU B CD2 1 
ATOM 1713 N N   . SER B 1 175 ? 129.025 135.195 152.838 1.00 46.01  ? 265 SER B N   1 
ATOM 1714 C CA  . SER B 1 175 ? 130.018 135.948 153.588 1.00 46.01  ? 265 SER B CA  1 
ATOM 1715 C C   . SER B 1 175 ? 129.372 136.703 154.739 1.00 46.01  ? 265 SER B C   1 
ATOM 1716 O O   . SER B 1 175 ? 129.832 136.625 155.890 1.00 46.01  ? 265 SER B O   1 
ATOM 1717 C CB  . SER B 1 175 ? 130.748 136.911 152.669 1.00 46.01  ? 265 SER B CB  1 
ATOM 1718 O OG  . SER B 1 175 ? 131.605 137.742 153.422 1.00 46.01  ? 265 SER B OG  1 
ATOM 1719 N N   . ARG B 1 176 ? 128.287 137.419 154.453 1.00 51.92  ? 266 ARG B N   1 
ATOM 1720 C CA  . ARG B 1 176 ? 127.628 138.156 155.519 1.00 51.92  ? 266 ARG B CA  1 
ATOM 1721 C C   . ARG B 1 176 ? 127.201 137.223 156.634 1.00 51.92  ? 266 ARG B C   1 
ATOM 1722 O O   . ARG B 1 176 ? 127.609 137.390 157.789 1.00 51.92  ? 266 ARG B O   1 
ATOM 1723 C CB  . ARG B 1 176 ? 126.411 138.901 154.994 1.00 51.92  ? 266 ARG B CB  1 
ATOM 1724 C CG  . ARG B 1 176 ? 125.576 139.480 156.117 1.00 51.92  ? 266 ARG B CG  1 
ATOM 1725 C CD  . ARG B 1 176 ? 124.163 139.727 155.674 1.00 51.92  ? 266 ARG B CD  1 
ATOM 1726 N NE  . ARG B 1 176 ? 123.608 138.568 155.002 1.00 51.92  ? 266 ARG B NE  1 
ATOM 1727 C CZ  . ARG B 1 176 ? 122.475 138.598 154.319 1.00 51.92  ? 266 ARG B CZ  1 
ATOM 1728 N NH1 . ARG B 1 176 ? 121.797 139.729 154.223 1.00 51.92  ? 266 ARG B NH1 1 
ATOM 1729 N NH2 . ARG B 1 176 ? 122.019 137.504 153.733 1.00 51.92  ? 266 ARG B NH2 1 
ATOM 1730 N N   . ASN B 1 177 ? 126.389 136.221 156.297 1.00 55.74  ? 267 ASN B N   1 
ATOM 1731 C CA  . ASN B 1 177 ? 125.786 135.398 157.334 1.00 55.74  ? 267 ASN B CA  1 
ATOM 1732 C C   . ASN B 1 177 ? 126.849 134.723 158.179 1.00 55.74  ? 267 ASN B C   1 
ATOM 1733 O O   . ASN B 1 177 ? 126.631 134.484 159.369 1.00 55.74  ? 267 ASN B O   1 
ATOM 1734 C CB  . ASN B 1 177 ? 124.825 134.378 156.720 1.00 55.74  ? 267 ASN B CB  1 
ATOM 1735 C CG  . ASN B 1 177 ? 123.705 133.978 157.677 1.00 55.74  ? 267 ASN B CG  1 
ATOM 1736 O OD1 . ASN B 1 177 ? 123.884 133.956 158.887 1.00 55.74  ? 267 ASN B OD1 1 
ATOM 1737 N ND2 . ASN B 1 177 ? 122.533 133.710 157.132 1.00 55.74  ? 267 ASN B ND2 1 
ATOM 1738 N N   . ASN B 1 178 ? 128.024 134.458 157.611 1.00 57.05  ? 268 ASN B N   1 
ATOM 1739 C CA  . ASN B 1 178 ? 129.071 133.860 158.428 1.00 57.05  ? 268 ASN B CA  1 
ATOM 1740 C C   . ASN B 1 178 ? 129.690 134.882 159.365 1.00 57.05  ? 268 ASN B C   1 
ATOM 1741 O O   . ASN B 1 178 ? 129.958 134.570 160.533 1.00 57.05  ? 268 ASN B O   1 
ATOM 1742 C CB  . ASN B 1 178 ? 130.135 133.215 157.551 1.00 57.05  ? 268 ASN B CB  1 
ATOM 1743 C CG  . ASN B 1 178 ? 130.003 131.718 157.498 1.00 57.05  ? 268 ASN B CG  1 
ATOM 1744 O OD1 . ASN B 1 178 ? 130.782 130.989 158.109 1.00 57.05  ? 268 ASN B OD1 1 
ATOM 1745 N ND2 . ASN B 1 178 ? 128.997 131.244 156.773 1.00 57.05  ? 268 ASN B ND2 1 
ATOM 1746 N N   . ASN B 1 179 ? 129.938 136.106 158.886 1.00 58.89  ? 269 ASN B N   1 
ATOM 1747 C CA  . ASN B 1 179 ? 130.328 137.137 159.843 1.00 58.89  ? 269 ASN B CA  1 
ATOM 1748 C C   . ASN B 1 179 ? 129.316 137.232 160.959 1.00 58.89  ? 269 ASN B C   1 
ATOM 1749 O O   . ASN B 1 179 ? 129.670 137.521 162.105 1.00 58.89  ? 269 ASN B O   1 
ATOM 1750 C CB  . ASN B 1 179 ? 130.494 138.505 159.192 1.00 58.89  ? 269 ASN B CB  1 
ATOM 1751 C CG  . ASN B 1 179 ? 131.915 138.769 158.731 1.00 58.89  ? 269 ASN B CG  1 
ATOM 1752 O OD1 . ASN B 1 179 ? 132.866 138.357 159.381 1.00 58.89  ? 269 ASN B OD1 1 
ATOM 1753 N ND2 . ASN B 1 179 ? 132.065 139.503 157.641 1.00 58.89  ? 269 ASN B ND2 1 
ATOM 1754 N N   . MET B 1 180 ? 128.048 136.996 160.642 1.00 61.70  ? 270 MET B N   1 
ATOM 1755 C CA  . MET B 1 180 ? 127.018 137.105 161.664 1.00 61.70  ? 270 MET B CA  1 
ATOM 1756 C C   . MET B 1 180 ? 127.286 136.165 162.834 1.00 61.70  ? 270 MET B C   1 
ATOM 1757 O O   . MET B 1 180 ? 127.442 136.627 163.970 1.00 61.70  ? 270 MET B O   1 
ATOM 1758 C CB  . MET B 1 180 ? 125.646 136.840 161.060 1.00 61.70  ? 270 MET B CB  1 
ATOM 1759 C CG  . MET B 1 180 ? 124.957 138.072 160.528 1.00 61.70  ? 270 MET B CG  1 
ATOM 1760 S SD  . MET B 1 180 ? 123.321 137.686 159.882 1.00 61.70  ? 270 MET B SD  1 
ATOM 1761 C CE  . MET B 1 180 ? 122.265 138.392 161.134 1.00 61.70  ? 270 MET B CE  1 
ATOM 1762 N N   . ILE B 1 181 ? 127.354 134.855 162.587 1.00 56.49  ? 271 ILE B N   1 
ATOM 1763 C CA  . ILE B 1 181 ? 127.668 133.935 163.674 1.00 56.49  ? 271 ILE B CA  1 
ATOM 1764 C C   . ILE B 1 181 ? 128.983 134.320 164.317 1.00 56.49  ? 271 ILE B C   1 
ATOM 1765 O O   . ILE B 1 181 ? 129.091 134.384 165.546 1.00 56.49  ? 271 ILE B O   1 
ATOM 1766 C CB  . ILE B 1 181 ? 127.726 132.486 163.175 1.00 56.49  ? 271 ILE B CB  1 
ATOM 1767 C CG1 . ILE B 1 181 ? 126.342 131.966 162.839 1.00 56.49  ? 271 ILE B CG1 1 
ATOM 1768 C CG2 . ILE B 1 181 ? 128.317 131.613 164.240 1.00 56.49  ? 271 ILE B CG2 1 
ATOM 1769 C CD1 . ILE B 1 181 ? 126.394 130.630 162.154 1.00 56.49  ? 271 ILE B CD1 1 
ATOM 1770 N N   . MET B 1 182 ? 129.996 134.594 163.496 1.00 64.60  ? 272 MET B N   1 
ATOM 1771 C CA  . MET B 1 182 ? 131.316 134.883 164.034 1.00 64.60  ? 272 MET B CA  1 
ATOM 1772 C C   . MET B 1 182 ? 131.271 136.023 165.037 1.00 64.60  ? 272 MET B C   1 
ATOM 1773 O O   . MET B 1 182 ? 132.059 136.052 165.989 1.00 64.60  ? 272 MET B O   1 
ATOM 1774 C CB  . MET B 1 182 ? 132.276 135.199 162.897 1.00 64.60  ? 272 MET B CB  1 
ATOM 1775 C CG  . MET B 1 182 ? 133.227 134.075 162.607 1.00 64.60  ? 272 MET B CG  1 
ATOM 1776 S SD  . MET B 1 182 ? 134.271 133.854 164.049 1.00 64.60  ? 272 MET B SD  1 
ATOM 1777 C CE  . MET B 1 182 ? 135.305 132.506 163.519 1.00 64.60  ? 272 MET B CE  1 
ATOM 1778 N N   . ARG B 1 183 ? 130.352 136.965 164.847 1.00 71.97  ? 273 ARG B N   1 
ATOM 1779 C CA  . ARG B 1 183 ? 130.270 138.096 165.758 1.00 71.97  ? 273 ARG B CA  1 
ATOM 1780 C C   . ARG B 1 183 ? 129.885 137.685 167.169 1.00 71.97  ? 273 ARG B C   1 
ATOM 1781 O O   . ARG B 1 183 ? 130.203 138.409 168.118 1.00 71.97  ? 273 ARG B O   1 
ATOM 1782 C CB  . ARG B 1 183 ? 129.270 139.111 165.231 1.00 71.97  ? 273 ARG B CB  1 
ATOM 1783 C CG  . ARG B 1 183 ? 129.224 140.390 166.020 1.00 71.97  ? 273 ARG B CG  1 
ATOM 1784 C CD  . ARG B 1 183 ? 130.506 141.155 165.872 1.00 71.97  ? 273 ARG B CD  1 
ATOM 1785 N NE  . ARG B 1 183 ? 130.682 142.096 166.962 1.00 71.97  ? 273 ARG B NE  1 
ATOM 1786 C CZ  . ARG B 1 183 ? 131.075 141.747 168.176 1.00 71.97  ? 273 ARG B CZ  1 
ATOM 1787 N NH1 . ARG B 1 183 ? 131.333 140.475 168.441 1.00 71.97  ? 273 ARG B NH1 1 
ATOM 1788 N NH2 . ARG B 1 183 ? 131.214 142.663 169.121 1.00 71.97  ? 273 ARG B NH2 1 
ATOM 1789 N N   . SER B 1 184 ? 129.229 136.536 167.334 1.00 71.08  ? 274 SER B N   1 
ATOM 1790 C CA  . SER B 1 184 ? 128.751 136.145 168.654 1.00 71.08  ? 274 SER B CA  1 
ATOM 1791 C C   . SER B 1 184 ? 129.887 135.798 169.603 1.00 71.08  ? 274 SER B C   1 
ATOM 1792 O O   . SER B 1 184 ? 129.666 135.691 170.812 1.00 71.08  ? 274 SER B O   1 
ATOM 1793 C CB  . SER B 1 184 ? 127.797 134.963 168.540 1.00 71.08  ? 274 SER B CB  1 
ATOM 1794 O OG  . SER B 1 184 ? 126.512 135.312 169.016 1.00 71.08  ? 274 SER B OG  1 
ATOM 1795 N N   . PHE B 1 185 ? 131.095 135.607 169.091 1.00 77.51  ? 275 PHE B N   1 
ATOM 1796 C CA  . PHE B 1 185 ? 132.210 135.187 169.923 1.00 77.51  ? 275 PHE B CA  1 
ATOM 1797 C C   . PHE B 1 185 ? 133.286 136.246 170.072 1.00 77.51  ? 275 PHE B C   1 
ATOM 1798 O O   . PHE B 1 185 ? 134.443 135.893 170.309 1.00 77.51  ? 275 PHE B O   1 
ATOM 1799 C CB  . PHE B 1 185 ? 132.824 133.910 169.363 1.00 77.51  ? 275 PHE B CB  1 
ATOM 1800 C CG  . PHE B 1 185 ? 131.964 132.718 169.553 1.00 77.51  ? 275 PHE B CG  1 
ATOM 1801 C CD1 . PHE B 1 185 ? 131.933 132.071 170.767 1.00 77.51  ? 275 PHE B CD1 1 
ATOM 1802 C CD2 . PHE B 1 185 ? 131.162 132.261 168.535 1.00 77.51  ? 275 PHE B CD2 1 
ATOM 1803 C CE1 . PHE B 1 185 ? 131.133 130.978 170.956 1.00 77.51  ? 275 PHE B CE1 1 
ATOM 1804 C CE2 . PHE B 1 185 ? 130.359 131.165 168.718 1.00 77.51  ? 275 PHE B CE2 1 
ATOM 1805 C CZ  . PHE B 1 185 ? 130.344 130.523 169.930 1.00 77.51  ? 275 PHE B CZ  1 
ATOM 1806 N N   . ARG B 1 186 ? 132.938 137.524 169.952 1.00 80.62  ? 276 ARG B N   1 
ATOM 1807 C CA  . ARG B 1 186 ? 133.914 138.610 170.021 1.00 80.62  ? 276 ARG B CA  1 
ATOM 1808 C C   . ARG B 1 186 ? 135.047 138.410 169.022 1.00 80.62  ? 276 ARG B C   1 
ATOM 1809 O O   . ARG B 1 186 ? 136.206 138.718 169.309 1.00 80.62  ? 276 ARG B O   1 
ATOM 1810 C CB  . ARG B 1 186 ? 134.481 138.728 171.437 1.00 50.00  ? 276 ARG B CB  1 
ATOM 1811 C CG  . ARG B 1 186 ? 133.465 139.176 172.476 1.00 50.00  ? 276 ARG B CG  1 
ATOM 1812 C CD  . ARG B 1 186 ? 134.038 139.339 173.875 1.00 50.00  ? 276 ARG B CD  1 
ATOM 1813 N NE  . ARG B 1 186 ? 133.012 139.702 174.848 1.00 50.00  ? 276 ARG B NE  1 
ATOM 1814 C CZ  . ARG B 1 186 ? 133.223 139.793 176.153 1.00 50.00  ? 276 ARG B CZ  1 
ATOM 1815 N NH1 . ARG B 1 186 ? 134.429 139.551 176.652 1.00 50.00  ? 276 ARG B NH1 1 
ATOM 1816 N NH2 . ARG B 1 186 ? 132.229 140.129 176.966 1.00 50.00  ? 276 ARG B NH2 1 
ATOM 1817 N N   . GLN B 1 187 ? 134.705 137.880 167.853 1.00 74.18  ? 277 GLN B N   1 
ATOM 1818 C CA  . GLN B 1 187 ? 135.705 137.655 166.821 1.00 74.18  ? 277 GLN B CA  1 
ATOM 1819 C C   . GLN B 1 187 ? 135.565 138.702 165.733 1.00 74.18  ? 277 GLN B C   1 
ATOM 1820 O O   . GLN B 1 187 ? 134.452 139.087 165.376 1.00 74.18  ? 277 GLN B O   1 
ATOM 1821 C CB  . GLN B 1 187 ? 135.538 136.267 166.215 1.00 74.18  ? 277 GLN B CB  1 
ATOM 1822 C CG  . GLN B 1 187 ? 135.301 135.168 167.234 1.00 74.18  ? 277 GLN B CG  1 
ATOM 1823 C CD  . GLN B 1 187 ? 136.477 134.963 168.167 1.00 74.18  ? 277 GLN B CD  1 
ATOM 1824 O OE1 . GLN B 1 187 ? 137.574 135.470 167.930 1.00 74.18  ? 277 GLN B OE1 1 
ATOM 1825 N NE2 . GLN B 1 187 ? 136.255 134.205 169.234 1.00 74.18  ? 277 GLN B NE2 1 
ATOM 1826 N N   . PRO B 1 188 ? 136.699 139.164 165.193 1.00 75.36  ? 278 PRO B N   1 
ATOM 1827 C CA  . PRO B 1 188 ? 136.648 140.195 164.159 1.00 75.36  ? 278 PRO B CA  1 
ATOM 1828 C C   . PRO B 1 188 ? 135.968 139.677 162.906 1.00 75.36  ? 278 PRO B C   1 
ATOM 1829 O O   . PRO B 1 188 ? 136.023 138.492 162.580 1.00 75.36  ? 278 PRO B O   1 
ATOM 1830 C CB  . PRO B 1 188 ? 138.123 140.511 163.896 1.00 75.36  ? 278 PRO B CB  1 
ATOM 1831 C CG  . PRO B 1 188 ? 138.864 139.925 165.059 1.00 75.36  ? 278 PRO B CG  1 
ATOM 1832 C CD  . PRO B 1 188 ? 138.072 138.747 165.494 1.00 75.36  ? 278 PRO B CD  1 
ATOM 1833 N N   . ILE B 1 189 ? 135.320 140.594 162.198 1.00 60.78  ? 279 ILE B N   1 
ATOM 1834 C CA  . ILE B 1 189 ? 134.641 140.278 160.950 1.00 60.78  ? 279 ILE B CA  1 
ATOM 1835 C C   . ILE B 1 189 ? 135.621 140.331 159.796 1.00 60.78  ? 279 ILE B C   1 
ATOM 1836 O O   . ILE B 1 189 ? 136.747 140.812 159.944 1.00 60.78  ? 279 ILE B O   1 
ATOM 1837 C CB  . ILE B 1 189 ? 133.483 141.244 160.699 1.00 60.78  ? 279 ILE B CB  1 
ATOM 1838 C CG1 . ILE B 1 189 ? 133.959 142.653 161.021 1.00 60.78  ? 279 ILE B CG1 1 
ATOM 1839 C CG2 . ILE B 1 189 ? 132.295 140.847 161.517 1.00 60.78  ? 279 ILE B CG2 1 
ATOM 1840 C CD1 . ILE B 1 189 ? 132.914 143.703 160.866 1.00 60.78  ? 279 ILE B CD1 1 
ATOM 1841 N N   . THR B 1 190 ? 135.196 139.843 158.641 1.00 52.32  ? 280 THR B N   1 
ATOM 1842 C CA  . THR B 1 190 ? 136.014 139.855 157.443 1.00 52.32  ? 280 THR B CA  1 
ATOM 1843 C C   . THR B 1 190 ? 135.386 140.758 156.396 1.00 52.32  ? 280 THR B C   1 
ATOM 1844 O O   . THR B 1 190 ? 134.217 141.128 156.488 1.00 52.32  ? 280 THR B O   1 
ATOM 1845 C CB  . THR B 1 190 ? 136.164 138.447 156.879 1.00 52.32  ? 280 THR B CB  1 
ATOM 1846 O OG1 . THR B 1 190 ? 135.028 138.154 156.066 1.00 52.32  ? 280 THR B OG1 1 
ATOM 1847 C CG2 . THR B 1 190 ? 136.225 137.445 158.006 1.00 52.32  ? 280 THR B CG2 1 
ATOM 1848 N N   . GLU B 1 191 ? 136.174 141.098 155.387 1.00 54.42  ? 281 GLU B N   1 
ATOM 1849 C CA  . GLU B 1 191 ? 135.718 141.966 154.306 1.00 54.42  ? 281 GLU B CA  1 
ATOM 1850 C C   . GLU B 1 191 ? 134.604 141.255 153.552 1.00 54.42  ? 281 GLU B C   1 
ATOM 1851 O O   . GLU B 1 191 ? 134.400 140.052 153.705 1.00 54.42  ? 281 GLU B O   1 
ATOM 1852 C CB  . GLU B 1 191 ? 136.885 142.316 153.391 1.00 54.42  ? 281 GLU B CB  1 
ATOM 1853 C CG  . GLU B 1 191 ? 136.639 143.475 152.429 1.00 54.42  ? 281 GLU B CG  1 
ATOM 1854 C CD  . GLU B 1 191 ? 137.867 143.823 151.592 1.00 54.42  ? 281 GLU B CD  1 
ATOM 1855 O OE1 . GLU B 1 191 ? 138.896 143.126 151.713 1.00 54.42  ? 281 GLU B OE1 1 
ATOM 1856 O OE2 . GLU B 1 191 ? 137.802 144.798 150.814 1.00 54.42  ? 281 GLU B OE2 1 
ATOM 1857 N N   . VAL B 1 192 ? 133.865 141.998 152.748 1.00 41.78  ? 282 VAL B N   1 
ATOM 1858 C CA  . VAL B 1 192 ? 132.690 141.438 152.076 1.00 41.78  ? 282 VAL B CA  1 
ATOM 1859 C C   . VAL B 1 192 ? 132.683 141.882 150.626 1.00 41.78  ? 282 VAL B C   1 
ATOM 1860 O O   . VAL B 1 192 ? 132.976 143.049 150.344 1.00 41.78  ? 282 VAL B O   1 
ATOM 1861 C CB  . VAL B 1 192 ? 131.433 141.891 152.791 1.00 41.78  ? 282 VAL B CB  1 
ATOM 1862 C CG1 . VAL B 1 192 ? 130.286 141.968 151.833 1.00 41.78  ? 282 VAL B CG1 1 
ATOM 1863 C CG2 . VAL B 1 192 ? 131.127 140.928 153.892 1.00 41.78  ? 282 VAL B CG2 1 
ATOM 1864 N N   . PRO B 1 193 ? 132.338 141.024 149.680 1.00 52.47  ? 283 PRO B N   1 
ATOM 1865 C CA  . PRO B 1 193 ? 132.391 141.427 148.278 1.00 52.47  ? 283 PRO B CA  1 
ATOM 1866 C C   . PRO B 1 193 ? 131.228 142.339 147.948 1.00 52.47  ? 283 PRO B C   1 
ATOM 1867 O O   . PRO B 1 193 ? 130.286 142.478 148.726 1.00 52.47  ? 283 PRO B O   1 
ATOM 1868 C CB  . PRO B 1 193 ? 132.283 140.105 147.515 1.00 52.47  ? 283 PRO B CB  1 
ATOM 1869 C CG  . PRO B 1 193 ? 132.277 139.038 148.559 1.00 52.47  ? 283 PRO B CG  1 
ATOM 1870 C CD  . PRO B 1 193 ? 131.810 139.668 149.820 1.00 52.47  ? 283 PRO B CD  1 
ATOM 1871 N N   . PHE B 1 194 ? 131.305 142.954 146.775 1.00 58.86  ? 284 PHE B N   1 
ATOM 1872 C CA  . PHE B 1 194 ? 130.224 143.799 146.312 1.00 58.86  ? 284 PHE B CA  1 
ATOM 1873 C C   . PHE B 1 194 ? 129.279 143.014 145.411 1.00 58.86  ? 284 PHE B C   1 
ATOM 1874 O O   . PHE B 1 194 ? 129.635 141.994 144.818 1.00 58.86  ? 284 PHE B O   1 
ATOM 1875 C CB  . PHE B 1 194 ? 130.770 145.011 145.569 1.00 58.86  ? 284 PHE B CB  1 
ATOM 1876 C CG  . PHE B 1 194 ? 131.197 146.119 146.467 1.00 58.86  ? 284 PHE B CG  1 
ATOM 1877 C CD1 . PHE B 1 194 ? 130.761 146.167 147.766 1.00 58.86  ? 284 PHE B CD1 1 
ATOM 1878 C CD2 . PHE B 1 194 ? 132.028 147.115 146.011 1.00 58.86  ? 284 PHE B CD2 1 
ATOM 1879 C CE1 . PHE B 1 194 ? 131.149 147.182 148.592 1.00 58.86  ? 284 PHE B CE1 1 
ATOM 1880 C CE2 . PHE B 1 194 ? 132.410 148.134 146.832 1.00 58.86  ? 284 PHE B CE2 1 
ATOM 1881 C CZ  . PHE B 1 194 ? 131.976 148.166 148.125 1.00 58.86  ? 284 PHE B CZ  1 
ATOM 1882 N N   . PHE B 1 195 ? 128.067 143.538 145.283 1.00 62.11  ? 285 PHE B N   1 
ATOM 1883 C CA  . PHE B 1 195 ? 126.989 142.918 144.532 1.00 62.11  ? 285 PHE B CA  1 
ATOM 1884 C C   . PHE B 1 195 ? 127.412 142.538 143.118 1.00 62.11  ? 285 PHE B C   1 
ATOM 1885 O O   . PHE B 1 195 ? 126.741 141.741 142.461 1.00 62.11  ? 285 PHE B O   1 
ATOM 1886 C CB  . PHE B 1 195 ? 125.800 143.874 144.524 1.00 62.11  ? 285 PHE B CB  1 
ATOM 1887 C CG  . PHE B 1 195 ? 124.874 143.685 143.378 1.00 62.11  ? 285 PHE B CG  1 
ATOM 1888 C CD1 . PHE B 1 195 ? 124.881 144.571 142.321 1.00 62.11  ? 285 PHE B CD1 1 
ATOM 1889 C CD2 . PHE B 1 195 ? 123.976 142.641 143.363 1.00 62.11  ? 285 PHE B CD2 1 
ATOM 1890 C CE1 . PHE B 1 195 ? 124.025 144.411 141.258 1.00 62.11  ? 285 PHE B CE1 1 
ATOM 1891 C CE2 . PHE B 1 195 ? 123.115 142.478 142.301 1.00 62.11  ? 285 PHE B CE2 1 
ATOM 1892 C CZ  . PHE B 1 195 ? 123.139 143.365 141.247 1.00 62.11  ? 285 PHE B CZ  1 
ATOM 1893 N N   . ASN B 1 196 ? 128.531 143.073 142.640 1.00 56.12  ? 286 ASN B N   1 
ATOM 1894 C CA  . ASN B 1 196 ? 129.043 142.741 141.319 1.00 56.12  ? 286 ASN B CA  1 
ATOM 1895 C C   . ASN B 1 196 ? 130.313 141.909 141.375 1.00 56.12  ? 286 ASN B C   1 
ATOM 1896 O O   . ASN B 1 196 ? 130.819 141.507 140.326 1.00 56.12  ? 286 ASN B O   1 
ATOM 1897 C CB  . ASN B 1 196 ? 129.303 144.013 140.527 1.00 56.12  ? 286 ASN B CB  1 
ATOM 1898 C CG  . ASN B 1 196 ? 130.483 144.778 141.060 1.00 56.12  ? 286 ASN B CG  1 
ATOM 1899 O OD1 . ASN B 1 196 ? 130.726 144.789 142.263 1.00 56.12  ? 286 ASN B OD1 1 
ATOM 1900 N ND2 . ASN B 1 196 ? 131.219 145.434 140.175 1.00 56.12  ? 286 ASN B ND2 1 
ATOM 1901 N N   . GLY B 1 197 ? 130.851 141.653 142.566 1.00 61.27  ? 287 GLY B N   1 
ATOM 1902 C CA  . GLY B 1 197 ? 131.948 140.719 142.730 1.00 61.27  ? 287 GLY B CA  1 
ATOM 1903 C C   . GLY B 1 197 ? 133.283 141.297 143.153 1.00 61.27  ? 287 GLY B C   1 
ATOM 1904 O O   . GLY B 1 197 ? 133.975 140.670 143.967 1.00 61.27  ? 287 GLY B O   1 
ATOM 1905 N N   . ASP B 1 198 ? 133.671 142.459 142.640 1.00 68.47  ? 288 ASP B N   1 
ATOM 1906 C CA  . ASP B 1 198 ? 134.967 143.050 142.933 1.00 68.47  ? 288 ASP B CA  1 
ATOM 1907 C C   . ASP B 1 198 ? 135.143 143.242 144.429 1.00 68.47  ? 288 ASP B C   1 
ATOM 1908 O O   . ASP B 1 198 ? 134.185 143.214 145.201 1.00 68.47  ? 288 ASP B O   1 
ATOM 1909 C CB  . ASP B 1 198 ? 135.116 144.404 142.247 1.00 68.47  ? 288 ASP B CB  1 
ATOM 1910 C CG  . ASP B 1 198 ? 134.680 144.373 140.810 1.00 68.47  ? 288 ASP B CG  1 
ATOM 1911 O OD1 . ASP B 1 198 ? 134.981 143.375 140.127 1.00 68.47  ? 288 ASP B OD1 1 
ATOM 1912 O OD2 . ASP B 1 198 ? 134.040 145.345 140.360 1.00 68.47  ? 288 ASP B OD2 1 
ATOM 1913 N N   . ILE B 1 199 ? 136.387 143.431 144.838 1.00 67.75  ? 289 ILE B N   1 
ATOM 1914 C CA  . ILE B 1 199 ? 136.650 143.896 146.192 1.00 67.75  ? 289 ILE B CA  1 
ATOM 1915 C C   . ILE B 1 199 ? 136.365 145.388 146.177 1.00 67.75  ? 289 ILE B C   1 
ATOM 1916 O O   . ILE B 1 199 ? 136.471 146.021 145.118 1.00 67.75  ? 289 ILE B O   1 
ATOM 1917 C CB  . ILE B 1 199 ? 138.078 143.548 146.639 1.00 67.75  ? 289 ILE B CB  1 
ATOM 1918 C CG1 . ILE B 1 199 ? 138.031 142.521 147.777 1.00 67.75  ? 289 ILE B CG1 1 
ATOM 1919 C CG2 . ILE B 1 199 ? 138.838 144.784 147.068 1.00 67.75  ? 289 ILE B CG2 1 
ATOM 1920 C CD1 . ILE B 1 199 ? 138.669 141.184 147.432 1.00 67.75  ? 289 ILE B CD1 1 
ATOM 1921 N N   . PRO B 1 200 ? 135.951 145.980 147.295 1.00 73.88  ? 290 PRO B N   1 
ATOM 1922 C CA  . PRO B 1 200 ? 135.613 147.404 147.306 1.00 73.88  ? 290 PRO B CA  1 
ATOM 1923 C C   . PRO B 1 200 ? 136.773 148.270 146.844 1.00 73.88  ? 290 PRO B C   1 
ATOM 1924 O O   . PRO B 1 200 ? 137.888 147.791 146.637 1.00 73.88  ? 290 PRO B O   1 
ATOM 1925 C CB  . PRO B 1 200 ? 135.277 147.673 148.775 1.00 73.88  ? 290 PRO B CB  1 
ATOM 1926 C CG  . PRO B 1 200 ? 134.880 146.373 149.306 1.00 73.88  ? 290 PRO B CG  1 
ATOM 1927 C CD  . PRO B 1 200 ? 135.699 145.350 148.596 1.00 73.88  ? 290 PRO B CD  1 
ATOM 1928 N N   . ASP B 1 201 ? 136.500 149.559 146.675 1.00 98.89  ? 291 ASP B N   1 
ATOM 1929 C CA  . ASP B 1 201 ? 137.562 150.480 146.319 1.00 98.89  ? 291 ASP B CA  1 
ATOM 1930 C C   . ASP B 1 201 ? 138.650 150.440 147.395 1.00 98.89  ? 291 ASP B C   1 
ATOM 1931 O O   . ASP B 1 201 ? 138.382 150.817 148.543 1.00 98.89  ? 291 ASP B O   1 
ATOM 1932 C CB  . ASP B 1 201 ? 137.043 151.901 146.158 1.00 98.89  ? 291 ASP B CB  1 
ATOM 1933 C CG  . ASP B 1 201 ? 138.114 152.845 145.658 1.00 98.89  ? 291 ASP B CG  1 
ATOM 1934 O OD1 . ASP B 1 201 ? 138.030 153.267 144.487 1.00 98.89  ? 291 ASP B OD1 1 
ATOM 1935 O OD2 . ASP B 1 201 ? 139.050 153.141 146.423 1.00 98.89  ? 291 ASP B OD2 1 
ATOM 1936 N N   . PRO B 1 202 ? 139.859 150.006 147.059 1.00 100.93 ? 292 PRO B N   1 
ATOM 1937 C CA  . PRO B 1 202 ? 140.872 149.783 148.105 1.00 100.93 ? 292 PRO B CA  1 
ATOM 1938 C C   . PRO B 1 202 ? 141.249 151.035 148.863 1.00 100.93 ? 292 PRO B C   1 
ATOM 1939 O O   . PRO B 1 202 ? 141.912 150.932 149.901 1.00 100.93 ? 292 PRO B O   1 
ATOM 1940 C CB  . PRO B 1 202 ? 142.064 149.218 147.322 1.00 100.93 ? 292 PRO B CB  1 
ATOM 1941 C CG  . PRO B 1 202 ? 141.477 148.724 146.030 1.00 100.93 ? 292 PRO B CG  1 
ATOM 1942 C CD  . PRO B 1 202 ? 140.359 149.659 145.723 1.00 100.93 ? 292 PRO B CD  1 
ATOM 1943 N N   . ASN B 1 203 ? 140.859 152.212 148.385 1.00 108.35 ? 293 ASN B N   1 
ATOM 1944 C CA  . ASN B 1 203 ? 140.928 153.406 149.209 1.00 108.35 ? 293 ASN B CA  1 
ATOM 1945 C C   . ASN B 1 203 ? 139.835 153.439 150.263 1.00 108.35 ? 293 ASN B C   1 
ATOM 1946 O O   . ASN B 1 203 ? 139.939 154.206 151.226 1.00 108.35 ? 293 ASN B O   1 
ATOM 1947 C CB  . ASN B 1 203 ? 140.824 154.661 148.343 1.00 108.35 ? 293 ASN B CB  1 
ATOM 1948 C CG  . ASN B 1 203 ? 140.924 155.933 149.150 1.00 108.35 ? 293 ASN B CG  1 
ATOM 1949 O OD1 . ASN B 1 203 ? 141.637 155.991 150.150 1.00 108.35 ? 293 ASN B OD1 1 
ATOM 1950 N ND2 . ASN B 1 203 ? 140.179 156.950 148.741 1.00 108.35 ? 293 ASN B ND2 1 
ATOM 1951 N N   . LEU B 1 204 ? 138.804 152.617 150.123 1.00 98.94  ? 294 LEU B N   1 
ATOM 1952 C CA  . LEU B 1 204 ? 137.718 152.667 151.078 1.00 98.94  ? 294 LEU B CA  1 
ATOM 1953 C C   . LEU B 1 204 ? 138.041 151.769 152.266 1.00 98.94  ? 294 LEU B C   1 
ATOM 1954 O O   . LEU B 1 204 ? 138.346 150.586 152.102 1.00 98.94  ? 294 LEU B O   1 
ATOM 1955 C CB  . LEU B 1 204 ? 136.407 152.247 150.431 1.00 98.94  ? 294 LEU B CB  1 
ATOM 1956 C CG  . LEU B 1 204 ? 135.678 153.323 149.616 1.00 98.94  ? 294 LEU B CG  1 
ATOM 1957 C CD1 . LEU B 1 204 ? 134.611 153.981 150.466 1.00 98.94  ? 294 LEU B CD1 1 
ATOM 1958 C CD2 . LEU B 1 204 ? 136.605 154.380 149.025 1.00 98.94  ? 294 LEU B CD2 1 
ATOM 1959 N N   . PRO B 1 205 ? 137.978 152.309 153.460 1.00 95.49  ? 295 PRO B N   1 
ATOM 1960 C CA  . PRO B 1 205 ? 138.562 151.626 154.619 1.00 95.49  ? 295 PRO B CA  1 
ATOM 1961 C C   . PRO B 1 205 ? 137.900 150.297 154.901 1.00 95.49  ? 295 PRO B C   1 
ATOM 1962 O O   . PRO B 1 205 ? 136.672 150.205 154.914 1.00 95.49  ? 295 PRO B O   1 
ATOM 1963 C CB  . PRO B 1 205 ? 138.328 152.616 155.767 1.00 95.49  ? 295 PRO B CB  1 
ATOM 1964 C CG  . PRO B 1 205 ? 137.899 153.898 155.112 1.00 95.49  ? 295 PRO B CG  1 
ATOM 1965 C CD  . PRO B 1 205 ? 137.245 153.522 153.836 1.00 95.49  ? 295 PRO B CD  1 
ATOM 1966 N N   . ARG B 1 206 ? 138.698 149.259 155.108 1.00 92.73  ? 296 ARG B N   1 
ATOM 1967 C CA  . ARG B 1 206 ? 138.155 147.954 155.459 1.00 92.73  ? 296 ARG B CA  1 
ATOM 1968 C C   . ARG B 1 206 ? 137.473 148.030 156.820 1.00 92.73  ? 296 ARG B C   1 
ATOM 1969 O O   . ARG B 1 206 ? 137.811 148.880 157.649 1.00 92.73  ? 296 ARG B O   1 
ATOM 1970 C CB  . ARG B 1 206 ? 139.259 146.906 155.444 1.00 92.73  ? 296 ARG B CB  1 
ATOM 1971 C CG  . ARG B 1 206 ? 139.642 146.471 154.047 1.00 92.73  ? 296 ARG B CG  1 
ATOM 1972 C CD  . ARG B 1 206 ? 141.082 146.017 153.978 1.00 92.73  ? 296 ARG B CD  1 
ATOM 1973 N NE  . ARG B 1 206 ? 141.332 145.240 152.770 1.00 92.73  ? 296 ARG B NE  1 
ATOM 1974 C CZ  . ARG B 1 206 ? 141.801 143.997 152.771 1.00 92.73  ? 296 ARG B CZ  1 
ATOM 1975 N NH1 . ARG B 1 206 ? 142.087 143.400 153.918 1.00 92.73  ? 296 ARG B NH1 1 
ATOM 1976 N NH2 . ARG B 1 206 ? 141.994 143.357 151.627 1.00 92.73  ? 296 ARG B NH2 1 
ATOM 1977 N N   . ILE B 1 207 ? 136.508 147.142 157.046 1.00 85.83  ? 297 ILE B N   1 
ATOM 1978 C CA  . ILE B 1 207 ? 135.588 147.247 158.174 1.00 85.83  ? 297 ILE B CA  1 
ATOM 1979 C C   . ILE B 1 207 ? 135.903 146.124 159.153 1.00 85.83  ? 297 ILE B C   1 
ATOM 1980 O O   . ILE B 1 207 ? 136.064 144.970 158.750 1.00 85.83  ? 297 ILE B O   1 
ATOM 1981 C CB  . ILE B 1 207 ? 134.140 147.172 157.699 1.00 85.83  ? 297 ILE B CB  1 
ATOM 1982 C CG1 . ILE B 1 207 ? 133.993 147.983 156.421 1.00 85.83  ? 297 ILE B CG1 1 
ATOM 1983 C CG2 . ILE B 1 207 ? 133.222 147.709 158.758 1.00 85.83  ? 297 ILE B CG2 1 
ATOM 1984 C CD1 . ILE B 1 207 ? 132.829 147.564 155.582 1.00 85.83  ? 297 ILE B CD1 1 
ATOM 1985 N N   . THR B 1 208 ? 135.979 146.446 160.444 1.00 90.26  ? 298 THR B N   1 
ATOM 1986 C CA  . THR B 1 208 ? 136.324 145.451 161.449 1.00 90.26  ? 298 THR B CA  1 
ATOM 1987 C C   . THR B 1 208 ? 135.367 145.406 162.620 1.00 90.26  ? 298 THR B C   1 
ATOM 1988 O O   . THR B 1 208 ? 135.218 144.346 163.234 1.00 90.26  ? 298 THR B O   1 
ATOM 1989 C CB  . THR B 1 208 ? 137.723 145.712 162.016 1.00 90.26  ? 298 THR B CB  1 
ATOM 1990 O OG1 . THR B 1 208 ? 137.715 146.960 162.720 1.00 90.26  ? 298 THR B OG1 1 
ATOM 1991 C CG2 . THR B 1 208 ? 138.748 145.771 160.903 1.00 90.26  ? 298 THR B CG2 1 
ATOM 1992 N N   . ARG B 1 209 ? 134.756 146.527 162.972 1.00 106.47 ? 299 ARG B N   1 
ATOM 1993 C CA  . ARG B 1 209 ? 133.830 146.575 164.084 1.00 106.47 ? 299 ARG B CA  1 
ATOM 1994 C C   . ARG B 1 209 ? 132.980 147.824 163.959 1.00 106.47 ? 299 ARG B C   1 
ATOM 1995 O O   . ARG B 1 209 ? 133.082 148.580 162.989 1.00 106.47 ? 299 ARG B O   1 
ATOM 1996 C CB  . ARG B 1 209 ? 134.573 146.519 165.418 1.00 106.47 ? 299 ARG B CB  1 
ATOM 1997 C CG  . ARG B 1 209 ? 135.887 147.253 165.422 1.00 106.47 ? 299 ARG B CG  1 
ATOM 1998 C CD  . ARG B 1 209 ? 136.657 146.886 166.667 1.00 106.47 ? 299 ARG B CD  1 
ATOM 1999 N NE  . ARG B 1 209 ? 136.655 145.442 166.881 1.00 106.47 ? 299 ARG B NE  1 
ATOM 2000 C CZ  . ARG B 1 209 ? 137.026 144.855 168.015 1.00 106.47 ? 299 ARG B CZ  1 
ATOM 2001 N NH1 . ARG B 1 209 ? 137.430 145.591 169.040 1.00 106.47 ? 299 ARG B NH1 1 
ATOM 2002 N NH2 . ARG B 1 209 ? 136.993 143.535 168.123 1.00 106.47 ? 299 ARG B NH2 1 
ATOM 2003 N N   . ILE B 1 210 ? 132.149 148.051 164.966 1.00 111.20 ? 300 ILE B N   1 
ATOM 2004 C CA  . ILE B 1 210 ? 131.048 148.977 164.779 1.00 111.20 ? 300 ILE B CA  1 
ATOM 2005 C C   . ILE B 1 210 ? 131.524 150.422 164.792 1.00 111.20 ? 300 ILE B C   1 
ATOM 2006 O O   . ILE B 1 210 ? 131.125 151.216 163.932 1.00 111.20 ? 300 ILE B O   1 
ATOM 2007 C CB  . ILE B 1 210 ? 129.976 148.705 165.841 1.00 111.20 ? 300 ILE B CB  1 
ATOM 2008 C CG1 . ILE B 1 210 ? 128.849 149.722 165.730 1.00 111.20 ? 300 ILE B CG1 1 
ATOM 2009 C CG2 . ILE B 1 210 ? 130.583 148.701 167.231 1.00 111.20 ? 300 ILE B CG2 1 
ATOM 2010 C CD1 . ILE B 1 210 ? 127.567 149.236 166.333 1.00 111.20 ? 300 ILE B CD1 1 
ATOM 2011 N N   . GLU B 1 211 ? 132.388 150.787 165.737 1.00 116.30 ? 301 GLU B N   1 
ATOM 2012 C CA  . GLU B 1 211 ? 132.854 152.166 165.812 1.00 116.30 ? 301 GLU B CA  1 
ATOM 2013 C C   . GLU B 1 211 ? 133.552 152.580 164.526 1.00 116.30 ? 301 GLU B C   1 
ATOM 2014 O O   . GLU B 1 211 ? 133.523 153.758 164.143 1.00 116.30 ? 301 GLU B O   1 
ATOM 2015 C CB  . GLU B 1 211 ? 133.781 152.328 167.013 1.00 116.30 ? 301 GLU B CB  1 
ATOM 2016 C CG  . GLU B 1 211 ? 135.121 151.633 166.864 1.00 116.30 ? 301 GLU B CG  1 
ATOM 2017 C CD  . GLU B 1 211 ? 135.055 150.157 167.200 1.00 116.30 ? 301 GLU B CD  1 
ATOM 2018 O OE1 . GLU B 1 211 ? 134.059 149.494 166.838 1.00 116.30 ? 301 GLU B OE1 1 
ATOM 2019 O OE2 . GLU B 1 211 ? 135.996 149.670 167.858 1.00 116.30 ? 301 GLU B OE2 1 
ATOM 2020 N N   . ASP B 1 212 ? 134.187 151.622 163.847 1.00 116.58 ? 302 ASP B N   1 
ATOM 2021 C CA  . ASP B 1 212 ? 134.742 151.893 162.529 1.00 116.58 ? 302 ASP B CA  1 
ATOM 2022 C C   . ASP B 1 212 ? 133.701 152.525 161.627 1.00 116.58 ? 302 ASP B C   1 
ATOM 2023 O O   . ASP B 1 212 ? 133.948 153.567 161.007 1.00 116.58 ? 302 ASP B O   1 
ATOM 2024 C CB  . ASP B 1 212 ? 135.276 150.606 161.910 1.00 116.58 ? 302 ASP B CB  1 
ATOM 2025 C CG  . ASP B 1 212 ? 135.774 150.805 160.492 1.00 116.58 ? 302 ASP B CG  1 
ATOM 2026 O OD1 . ASP B 1 212 ? 136.710 151.609 160.291 1.00 116.58 ? 302 ASP B OD1 1 
ATOM 2027 O OD2 . ASP B 1 212 ? 135.227 150.151 159.579 1.00 116.58 ? 302 ASP B OD2 1 
ATOM 2028 N N   . ILE B 1 213 ? 132.527 151.911 161.547 1.00 107.63 ? 303 ILE B N   1 
ATOM 2029 C CA  . ILE B 1 213 ? 131.433 152.531 160.820 1.00 107.63 ? 303 ILE B CA  1 
ATOM 2030 C C   . ILE B 1 213 ? 131.077 153.865 161.448 1.00 107.63 ? 303 ILE B C   1 
ATOM 2031 O O   . ILE B 1 213 ? 131.015 154.892 160.764 1.00 107.63 ? 303 ILE B O   1 
ATOM 2032 C CB  . ILE B 1 213 ? 130.222 151.592 160.785 1.00 107.63 ? 303 ILE B CB  1 
ATOM 2033 C CG1 . ILE B 1 213 ? 130.596 150.287 160.099 1.00 107.63 ? 303 ILE B CG1 1 
ATOM 2034 C CG2 . ILE B 1 213 ? 129.081 152.257 160.066 1.00 107.63 ? 303 ILE B CG2 1 
ATOM 2035 C CD1 . ILE B 1 213 ? 129.416 149.574 159.499 1.00 107.63 ? 303 ILE B CD1 1 
ATOM 2036 N N   . ASP B 1 214 ? 130.862 153.878 162.765 1.00 116.01 ? 304 ASP B N   1 
ATOM 2037 C CA  . ASP B 1 214 ? 130.335 155.071 163.420 1.00 116.01 ? 304 ASP B CA  1 
ATOM 2038 C C   . ASP B 1 214 ? 131.231 156.283 163.235 1.00 116.01 ? 304 ASP B C   1 
ATOM 2039 O O   . ASP B 1 214 ? 130.819 157.398 163.563 1.00 116.01 ? 304 ASP B O   1 
ATOM 2040 C CB  . ASP B 1 214 ? 130.121 154.819 164.911 1.00 116.01 ? 304 ASP B CB  1 
ATOM 2041 C CG  . ASP B 1 214 ? 128.985 155.651 165.484 1.00 116.01 ? 304 ASP B CG  1 
ATOM 2042 O OD1 . ASP B 1 214 ? 128.208 156.228 164.698 1.00 116.01 ? 304 ASP B OD1 1 
ATOM 2043 O OD2 . ASP B 1 214 ? 128.869 155.742 166.722 1.00 116.01 ? 304 ASP B OD2 1 
ATOM 2044 N N   . SER B 1 215 ? 132.446 156.086 162.730 1.00 119.19 ? 305 SER B N   1 
ATOM 2045 C CA  . SER B 1 215 ? 133.346 157.196 162.466 1.00 119.19 ? 305 SER B CA  1 
ATOM 2046 C C   . SER B 1 215 ? 133.419 157.570 160.994 1.00 119.19 ? 305 SER B C   1 
ATOM 2047 O O   . SER B 1 215 ? 134.165 158.488 160.642 1.00 119.19 ? 305 SER B O   1 
ATOM 2048 C CB  . SER B 1 215 ? 134.746 156.855 162.972 1.00 119.19 ? 305 SER B CB  1 
ATOM 2049 O OG  . SER B 1 215 ? 135.667 156.763 161.900 1.00 119.19 ? 305 SER B OG  1 
ATOM 2050 N N   . LEU B 1 216 ? 132.671 156.895 160.132 1.00 113.49 ? 306 LEU B N   1 
ATOM 2051 C CA  . LEU B 1 216 ? 132.868 157.057 158.701 1.00 113.49 ? 306 LEU B CA  1 
ATOM 2052 C C   . LEU B 1 216 ? 132.235 158.350 158.201 1.00 113.49 ? 306 LEU B C   1 
ATOM 2053 O O   . LEU B 1 216 ? 131.361 158.928 158.853 1.00 113.49 ? 306 LEU B O   1 
ATOM 2054 C CB  . LEU B 1 216 ? 132.282 155.859 157.963 1.00 113.49 ? 306 LEU B CB  1 
ATOM 2055 C CG  . LEU B 1 216 ? 132.614 155.761 156.478 1.00 113.49 ? 306 LEU B CG  1 
ATOM 2056 C CD1 . LEU B 1 216 ? 134.097 156.015 156.270 1.00 113.49 ? 306 LEU B CD1 1 
ATOM 2057 C CD2 . LEU B 1 216 ? 132.211 154.415 155.920 1.00 113.49 ? 306 LEU B CD2 1 
ATOM 2058 N N   . SER B 1 217 ? 132.691 158.808 157.036 1.00 113.06 ? 307 SER B N   1 
ATOM 2059 C CA  . SER B 1 217 ? 132.114 159.975 156.386 1.00 113.06 ? 307 SER B CA  1 
ATOM 2060 C C   . SER B 1 217 ? 130.828 159.604 155.657 1.00 113.06 ? 307 SER B C   1 
ATOM 2061 O O   . SER B 1 217 ? 130.593 158.447 155.297 1.00 113.06 ? 307 SER B O   1 
ATOM 2062 C CB  . SER B 1 217 ? 133.098 160.583 155.393 1.00 113.06 ? 307 SER B CB  1 
ATOM 2063 O OG  . SER B 1 217 ? 132.627 160.416 154.068 1.00 113.06 ? 307 SER B OG  1 
ATOM 2064 N N   . GLU B 1 218 ? 129.995 160.618 155.424 1.00 111.54 ? 308 GLU B N   1 
ATOM 2065 C CA  . GLU B 1 218 ? 128.676 160.376 154.848 1.00 111.54 ? 308 GLU B CA  1 
ATOM 2066 C C   . GLU B 1 218 ? 128.789 159.867 153.416 1.00 111.54 ? 308 GLU B C   1 
ATOM 2067 O O   . GLU B 1 218 ? 128.126 158.892 153.045 1.00 111.54 ? 308 GLU B O   1 
ATOM 2068 C CB  . GLU B 1 218 ? 127.829 161.654 154.970 1.00 111.54 ? 308 GLU B CB  1 
ATOM 2069 C CG  . GLU B 1 218 ? 126.641 161.918 154.009 1.00 111.54 ? 308 GLU B CG  1 
ATOM 2070 C CD  . GLU B 1 218 ? 126.974 161.866 152.528 1.00 111.54 ? 308 GLU B CD  1 
ATOM 2071 O OE1 . GLU B 1 218 ? 127.960 162.510 152.128 1.00 111.54 ? 308 GLU B OE1 1 
ATOM 2072 O OE2 . GLU B 1 218 ? 126.260 161.175 151.784 1.00 111.54 ? 308 GLU B OE2 1 
ATOM 2073 N N   . GLU B 1 219 ? 129.604 160.522 152.593 1.00 110.92 ? 309 GLU B N   1 
ATOM 2074 C CA  . GLU B 1 219 ? 129.727 160.078 151.211 1.00 110.92 ? 309 GLU B CA  1 
ATOM 2075 C C   . GLU B 1 219 ? 130.208 158.640 151.153 1.00 110.92 ? 309 GLU B C   1 
ATOM 2076 O O   . GLU B 1 219 ? 129.760 157.857 150.309 1.00 110.92 ? 309 GLU B O   1 
ATOM 2077 C CB  . GLU B 1 219 ? 130.665 161.002 150.440 1.00 110.92 ? 309 GLU B CB  1 
ATOM 2078 C CG  . GLU B 1 219 ? 131.942 161.331 151.176 1.00 110.92 ? 309 GLU B CG  1 
ATOM 2079 C CD  . GLU B 1 219 ? 132.997 160.263 151.020 1.00 110.92 ? 309 GLU B CD  1 
ATOM 2080 O OE1 . GLU B 1 219 ? 132.878 159.438 150.091 1.00 110.92 ? 309 GLU B OE1 1 
ATOM 2081 O OE2 . GLU B 1 219 ? 133.934 160.235 151.842 1.00 110.92 ? 309 GLU B OE2 1 
ATOM 2082 N N   . ASN B 1 220 ? 131.110 158.269 152.056 1.00 103.62 ? 310 ASN B N   1 
ATOM 2083 C CA  . ASN B 1 220 ? 131.561 156.889 152.101 1.00 103.62 ? 310 ASN B CA  1 
ATOM 2084 C C   . ASN B 1 220 ? 130.426 155.965 152.500 1.00 103.62 ? 310 ASN B C   1 
ATOM 2085 O O   . ASN B 1 220 ? 130.326 154.839 151.999 1.00 103.62 ? 310 ASN B O   1 
ATOM 2086 C CB  . ASN B 1 220 ? 132.725 156.755 153.070 1.00 103.62 ? 310 ASN B CB  1 
ATOM 2087 C CG  . ASN B 1 220 ? 134.009 157.281 152.497 1.00 103.62 ? 310 ASN B CG  1 
ATOM 2088 O OD1 . ASN B 1 220 ? 134.263 157.150 151.301 1.00 103.62 ? 310 ASN B OD1 1 
ATOM 2089 N ND2 . ASN B 1 220 ? 134.836 157.875 153.344 1.00 103.62 ? 310 ASN B ND2 1 
ATOM 2090 N N   . CYS B 1 221 ? 129.575 156.416 153.416 1.00 104.71 ? 311 CYS B N   1 
ATOM 2091 C CA  . CYS B 1 221 ? 128.402 155.630 153.767 1.00 104.71 ? 311 CYS B CA  1 
ATOM 2092 C C   . CYS B 1 221 ? 127.554 155.360 152.537 1.00 104.71 ? 311 CYS B C   1 
ATOM 2093 O O   . CYS B 1 221 ? 127.123 154.227 152.298 1.00 104.71 ? 311 CYS B O   1 
ATOM 2094 C CB  . CYS B 1 221 ? 127.585 156.355 154.832 1.00 104.71 ? 311 CYS B CB  1 
ATOM 2095 S SG  . CYS B 1 221 ? 125.898 155.744 155.006 1.00 104.71 ? 311 CYS B SG  1 
ATOM 2096 N N   . THR B 1 222 ? 127.295 156.398 151.750 1.00 93.32  ? 312 THR B N   1 
ATOM 2097 C CA  . THR B 1 222 ? 126.527 156.197 150.533 1.00 93.32  ? 312 THR B CA  1 
ATOM 2098 C C   . THR B 1 222 ? 127.230 155.241 149.591 1.00 93.32  ? 312 THR B C   1 
ATOM 2099 O O   . THR B 1 222 ? 126.592 154.352 149.018 1.00 93.32  ? 312 THR B O   1 
ATOM 2100 C CB  . THR B 1 222 ? 126.283 157.529 149.841 1.00 93.32  ? 312 THR B CB  1 
ATOM 2101 O OG1 . THR B 1 222 ? 127.538 158.192 149.650 1.00 93.32  ? 312 THR B OG1 1 
ATOM 2102 C CG2 . THR B 1 222 ? 125.367 158.392 150.679 1.00 93.32  ? 312 THR B CG2 1 
ATOM 2103 N N   . ARG B 1 223 ? 128.533 155.428 149.401 1.00 84.07  ? 313 ARG B N   1 
ATOM 2104 C CA  . ARG B 1 223 ? 129.290 154.503 148.574 1.00 84.07  ? 313 ARG B CA  1 
ATOM 2105 C C   . ARG B 1 223 ? 129.024 153.074 149.006 1.00 84.07  ? 313 ARG B C   1 
ATOM 2106 O O   . ARG B 1 223 ? 128.554 152.251 148.215 1.00 84.07  ? 313 ARG B O   1 
ATOM 2107 C CB  . ARG B 1 223 ? 130.781 154.820 148.660 1.00 84.07  ? 313 ARG B CB  1 
ATOM 2108 C CG  . ARG B 1 223 ? 131.159 156.164 148.088 1.00 84.07  ? 313 ARG B CG  1 
ATOM 2109 C CD  . ARG B 1 223 ? 132.660 156.319 148.016 1.00 84.07  ? 313 ARG B CD  1 
ATOM 2110 N NE  . ARG B 1 223 ? 133.258 155.245 147.237 1.00 84.07  ? 313 ARG B NE  1 
ATOM 2111 C CZ  . ARG B 1 223 ? 134.443 155.326 146.652 1.00 84.07  ? 313 ARG B CZ  1 
ATOM 2112 N NH1 . ARG B 1 223 ? 135.160 156.435 146.756 1.00 84.07  ? 313 ARG B NH1 1 
ATOM 2113 N NH2 . ARG B 1 223 ? 134.913 154.300 145.963 1.00 84.07  ? 313 ARG B NH2 1 
ATOM 2114 N N   . TYR B 1 224 ? 129.296 152.776 150.272 1.00 76.27  ? 314 TYR B N   1 
ATOM 2115 C CA  . TYR B 1 224 ? 129.013 151.450 150.795 1.00 76.27  ? 314 TYR B CA  1 
ATOM 2116 C C   . TYR B 1 224 ? 127.602 151.014 150.450 1.00 76.27  ? 314 TYR B C   1 
ATOM 2117 O O   . TYR B 1 224 ? 127.409 150.008 149.762 1.00 76.27  ? 314 TYR B O   1 
ATOM 2118 C CB  . TYR B 1 224 ? 129.233 151.425 152.301 1.00 76.27  ? 314 TYR B CB  1 
ATOM 2119 C CG  . TYR B 1 224 ? 130.597 150.940 152.707 1.00 76.27  ? 314 TYR B CG  1 
ATOM 2120 C CD1 . TYR B 1 224 ? 131.277 150.016 151.938 1.00 76.27  ? 314 TYR B CD1 1 
ATOM 2121 C CD2 . TYR B 1 224 ? 131.194 151.398 153.863 1.00 76.27  ? 314 TYR B CD2 1 
ATOM 2122 C CE1 . TYR B 1 224 ? 132.502 149.558 152.307 1.00 76.27  ? 314 TYR B CE1 1 
ATOM 2123 C CE2 . TYR B 1 224 ? 132.421 150.949 154.237 1.00 76.27  ? 314 TYR B CE2 1 
ATOM 2124 C CZ  . TYR B 1 224 ? 133.073 150.032 153.452 1.00 76.27  ? 314 TYR B CZ  1 
ATOM 2125 O OH  . TYR B 1 224 ? 134.311 149.585 153.825 1.00 76.27  ? 314 TYR B OH  1 
ATOM 2126 N N   . LEU B 1 225 ? 126.606 151.774 150.897 1.00 80.97  ? 315 LEU B N   1 
ATOM 2127 C CA  . LEU B 1 225 ? 125.225 151.372 150.673 1.00 80.97  ? 315 LEU B CA  1 
ATOM 2128 C C   . LEU B 1 225 ? 124.993 151.013 149.220 1.00 80.97  ? 315 LEU B C   1 
ATOM 2129 O O   . LEU B 1 225 ? 124.212 150.109 148.908 1.00 80.97  ? 315 LEU B O   1 
ATOM 2130 C CB  . LEU B 1 225 ? 124.269 152.468 151.115 1.00 80.97  ? 315 LEU B CB  1 
ATOM 2131 C CG  . LEU B 1 225 ? 124.087 152.479 152.620 1.00 80.97  ? 315 LEU B CG  1 
ATOM 2132 C CD1 . LEU B 1 225 ? 123.245 153.661 153.042 1.00 80.97  ? 315 LEU B CD1 1 
ATOM 2133 C CD2 . LEU B 1 225 ? 123.417 151.187 153.002 1.00 80.97  ? 315 LEU B CD2 1 
ATOM 2134 N N   . LYS B 1 226 ? 125.683 151.693 148.315 1.00 77.91  ? 316 LYS B N   1 
ATOM 2135 C CA  . LYS B 1 226 ? 125.595 151.286 146.923 1.00 77.91  ? 316 LYS B CA  1 
ATOM 2136 C C   . LYS B 1 226 ? 126.291 149.953 146.718 1.00 77.91  ? 316 LYS B C   1 
ATOM 2137 O O   . LYS B 1 226 ? 125.794 149.089 145.987 1.00 77.91  ? 316 LYS B O   1 
ATOM 2138 C CB  . LYS B 1 226 ? 126.191 152.354 146.017 1.00 77.91  ? 316 LYS B CB  1 
ATOM 2139 C CG  . LYS B 1 226 ? 125.869 152.135 144.554 1.00 77.91  ? 316 LYS B CG  1 
ATOM 2140 C CD  . LYS B 1 226 ? 124.378 152.229 144.304 1.00 77.91  ? 316 LYS B CD  1 
ATOM 2141 C CE  . LYS B 1 226 ? 123.867 153.608 144.651 1.00 77.91  ? 316 LYS B CE  1 
ATOM 2142 N NZ  . LYS B 1 226 ? 124.544 154.653 143.836 1.00 77.91  ? 316 LYS B NZ  1 
ATOM 2143 N N   . GLY B 1 227 ? 127.428 149.757 147.379 1.00 63.65  ? 317 GLY B N   1 
ATOM 2144 C CA  . GLY B 1 227 ? 128.191 148.540 147.174 1.00 63.65  ? 317 GLY B CA  1 
ATOM 2145 C C   . GLY B 1 227 ? 127.439 147.292 147.574 1.00 63.65  ? 317 GLY B C   1 
ATOM 2146 O O   . GLY B 1 227 ? 127.730 146.203 147.077 1.00 63.65  ? 317 GLY B O   1 
ATOM 2147 N N   . TYR B 1 228 ? 126.466 147.425 148.461 1.00 58.15  ? 318 TYR B N   1 
ATOM 2148 C CA  . TYR B 1 228 ? 125.707 146.268 148.898 1.00 58.15  ? 318 TYR B CA  1 
ATOM 2149 C C   . TYR B 1 228 ? 124.320 146.219 148.297 1.00 58.15  ? 318 TYR B C   1 
ATOM 2150 O O   . TYR B 1 228 ? 123.491 145.434 148.764 1.00 58.15  ? 318 TYR B O   1 
ATOM 2151 C CB  . TYR B 1 228 ? 125.591 146.257 150.411 1.00 58.15  ? 318 TYR B CB  1 
ATOM 2152 C CG  . TYR B 1 228 ? 126.861 145.913 151.115 1.00 58.15  ? 318 TYR B CG  1 
ATOM 2153 C CD1 . TYR B 1 228 ? 126.894 144.894 152.030 1.00 58.15  ? 318 TYR B CD1 1 
ATOM 2154 C CD2 . TYR B 1 228 ? 128.021 146.607 150.873 1.00 58.15  ? 318 TYR B CD2 1 
ATOM 2155 C CE1 . TYR B 1 228 ? 128.036 144.576 152.686 1.00 58.15  ? 318 TYR B CE1 1 
ATOM 2156 C CE2 . TYR B 1 228 ? 129.170 146.293 151.522 1.00 58.15  ? 318 TYR B CE2 1 
ATOM 2157 C CZ  . TYR B 1 228 ? 129.173 145.272 152.430 1.00 58.15  ? 318 TYR B CZ  1 
ATOM 2158 O OH  . TYR B 1 228 ? 130.318 144.935 153.097 1.00 58.15  ? 318 TYR B OH  1 
ATOM 2159 N N   . GLY B 1 229 ? 124.038 147.051 147.304 1.00 71.63  ? 319 GLY B N   1 
ATOM 2160 C CA  . GLY B 1 229 ? 122.759 146.988 146.633 1.00 71.63  ? 319 GLY B CA  1 
ATOM 2161 C C   . GLY B 1 229 ? 121.548 147.160 147.516 1.00 71.63  ? 319 GLY B C   1 
ATOM 2162 O O   . GLY B 1 229 ? 120.485 146.633 147.190 1.00 71.63  ? 319 GLY B O   1 
ATOM 2163 N N   . VAL B 1 230 ? 121.666 147.871 148.629 1.00 67.74  ? 320 VAL B N   1 
ATOM 2164 C CA  . VAL B 1 230 ? 120.518 148.085 149.501 1.00 67.74  ? 320 VAL B CA  1 
ATOM 2165 C C   . VAL B 1 230 ? 120.133 149.557 149.460 1.00 67.74  ? 320 VAL B C   1 
ATOM 2166 O O   . VAL B 1 230 ? 120.981 150.439 149.627 1.00 67.74  ? 320 VAL B O   1 
ATOM 2167 C CB  . VAL B 1 230 ? 120.821 147.622 150.927 1.00 67.74  ? 320 VAL B CB  1 
ATOM 2168 C CG1 . VAL B 1 230 ? 121.074 146.138 150.922 1.00 67.74  ? 320 VAL B CG1 1 
ATOM 2169 C CG2 . VAL B 1 230 ? 122.024 148.341 151.457 1.00 67.74  ? 320 VAL B CG2 1 
ATOM 2170 N N   . SER B 1 231 ? 118.854 149.825 149.223 1.00 86.58  ? 321 SER B N   1 
ATOM 2171 C CA  . SER B 1 231 ? 118.410 151.190 148.980 1.00 86.58  ? 321 SER B CA  1 
ATOM 2172 C C   . SER B 1 231 ? 118.114 151.905 150.289 1.00 86.58  ? 321 SER B C   1 
ATOM 2173 O O   . SER B 1 231 ? 117.592 151.308 151.234 1.00 86.58  ? 321 SER B O   1 
ATOM 2174 C CB  . SER B 1 231 ? 117.177 151.204 148.090 1.00 86.58  ? 321 SER B CB  1 
ATOM 2175 O OG  . SER B 1 231 ? 116.690 152.527 147.968 1.00 86.58  ? 321 SER B OG  1 
ATOM 2176 N N   . TYR B 1 232 ? 118.429 153.190 150.324 1.00 96.33  ? 322 TYR B N   1 
ATOM 2177 C CA  . TYR B 1 232 ? 118.234 154.042 151.479 1.00 96.33  ? 322 TYR B CA  1 
ATOM 2178 C C   . TYR B 1 232 ? 117.507 155.302 151.050 1.00 96.33  ? 322 TYR B C   1 
ATOM 2179 O O   . TYR B 1 232 ? 117.198 155.495 149.873 1.00 96.33  ? 322 TYR B O   1 
ATOM 2180 C CB  . TYR B 1 232 ? 119.567 154.424 152.110 1.00 96.33  ? 322 TYR B CB  1 
ATOM 2181 C CG  . TYR B 1 232 ? 120.388 155.310 151.214 1.00 96.33  ? 322 TYR B CG  1 
ATOM 2182 C CD1 . TYR B 1 232 ? 120.980 154.808 150.072 1.00 96.33  ? 322 TYR B CD1 1 
ATOM 2183 C CD2 . TYR B 1 232 ? 120.567 156.646 151.504 1.00 96.33  ? 322 TYR B CD2 1 
ATOM 2184 C CE1 . TYR B 1 232 ? 121.727 155.606 149.248 1.00 96.33  ? 322 TYR B CE1 1 
ATOM 2185 C CE2 . TYR B 1 232 ? 121.317 157.454 150.689 1.00 96.33  ? 322 TYR B CE2 1 
ATOM 2186 C CZ  . TYR B 1 232 ? 121.896 156.927 149.561 1.00 96.33  ? 322 TYR B CZ  1 
ATOM 2187 O OH  . TYR B 1 232 ? 122.647 157.722 148.735 1.00 96.33  ? 322 TYR B OH  1 
ATOM 2188 N N   . ASP B 1 233 ? 117.251 156.172 152.018 1.00 119.09 ? 323 ASP B N   1 
ATOM 2189 C CA  . ASP B 1 233 ? 116.618 157.452 151.744 1.00 119.09 ? 323 ASP B CA  1 
ATOM 2190 C C   . ASP B 1 233 ? 117.655 158.562 151.835 1.00 119.09 ? 323 ASP B C   1 
ATOM 2191 O O   . ASP B 1 233 ? 118.511 158.551 152.723 1.00 119.09 ? 323 ASP B O   1 
ATOM 2192 C CB  . ASP B 1 233 ? 115.472 157.706 152.718 1.00 119.09 ? 323 ASP B CB  1 
ATOM 2193 C CG  . ASP B 1 233 ? 114.260 156.856 152.411 1.00 119.09 ? 323 ASP B CG  1 
ATOM 2194 O OD1 . ASP B 1 233 ? 114.319 156.071 151.442 1.00 119.09 ? 323 ASP B OD1 1 
ATOM 2195 O OD2 . ASP B 1 233 ? 113.250 156.970 153.134 1.00 119.09 ? 323 ASP B OD2 1 
ATOM 2196 N N   . GLU B 1 234 ? 117.569 159.519 150.917 1.00 127.12 ? 324 GLU B N   1 
ATOM 2197 C CA  . GLU B 1 234 ? 118.557 160.584 150.825 1.00 127.12 ? 324 GLU B CA  1 
ATOM 2198 C C   . GLU B 1 234 ? 118.489 161.559 151.987 1.00 127.12 ? 324 GLU B C   1 
ATOM 2199 O O   . GLU B 1 234 ? 119.441 162.318 152.194 1.00 127.12 ? 324 GLU B O   1 
ATOM 2200 C CB  . GLU B 1 234 ? 118.360 161.336 149.514 1.00 127.12 ? 324 GLU B CB  1 
ATOM 2201 C CG  . GLU B 1 234 ? 118.686 160.508 148.291 1.00 127.12 ? 324 GLU B CG  1 
ATOM 2202 C CD  . GLU B 1 234 ? 117.601 159.506 147.957 1.00 127.12 ? 324 GLU B CD  1 
ATOM 2203 O OE1 . GLU B 1 234 ? 116.581 159.465 148.677 1.00 127.12 ? 324 GLU B OE1 1 
ATOM 2204 O OE2 . GLU B 1 234 ? 117.771 158.758 146.975 1.00 127.12 ? 324 GLU B OE2 1 
ATOM 2205 N N   . ASN B 1 235 ? 117.398 161.553 152.744 1.00 132.82 ? 325 ASN B N   1 
ATOM 2206 C CA  . ASN B 1 235 ? 117.212 162.507 153.823 1.00 132.82 ? 325 ASN B CA  1 
ATOM 2207 C C   . ASN B 1 235 ? 117.394 161.885 155.198 1.00 132.82 ? 325 ASN B C   1 
ATOM 2208 O O   . ASN B 1 235 ? 117.909 162.550 156.103 1.00 132.82 ? 325 ASN B O   1 
ATOM 2209 C CB  . ASN B 1 235 ? 115.814 163.123 153.734 1.00 132.82 ? 325 ASN B CB  1 
ATOM 2210 C CG  . ASN B 1 235 ? 115.278 163.140 152.317 1.00 132.82 ? 325 ASN B CG  1 
ATOM 2211 O OD1 . ASN B 1 235 ? 116.035 163.061 151.353 1.00 132.82 ? 325 ASN B OD1 1 
ATOM 2212 N ND2 . ASN B 1 235 ? 113.963 163.235 152.186 1.00 132.82 ? 325 ASN B ND2 1 
ATOM 2213 N N   . ASP B 1 236 ? 117.004 160.626 155.367 1.00 119.80 ? 326 ASP B N   1 
ATOM 2214 C CA  . ASP B 1 236 ? 117.034 159.945 156.658 1.00 119.80 ? 326 ASP B CA  1 
ATOM 2215 C C   . ASP B 1 236 ? 118.432 159.373 156.838 1.00 119.80 ? 326 ASP B C   1 
ATOM 2216 O O   . ASP B 1 236 ? 118.693 158.208 156.537 1.00 119.80 ? 326 ASP B O   1 
ATOM 2217 C CB  . ASP B 1 236 ? 115.952 158.853 156.729 1.00 119.80 ? 326 ASP B CB  1 
ATOM 2218 C CG  . ASP B 1 236 ? 115.877 158.175 158.093 1.00 119.80 ? 326 ASP B CG  1 
ATOM 2219 O OD1 . ASP B 1 236 ? 116.930 157.877 158.700 1.00 119.80 ? 326 ASP B OD1 1 
ATOM 2220 O OD2 . ASP B 1 236 ? 114.745 157.935 158.561 1.00 119.80 ? 326 ASP B OD2 1 
ATOM 2221 N N   . GLN B 1 237 ? 119.339 160.209 157.338 1.00 114.65 ? 327 GLN B N   1 
ATOM 2222 C CA  . GLN B 1 237 ? 120.639 159.706 157.742 1.00 114.65 ? 327 GLN B CA  1 
ATOM 2223 C C   . GLN B 1 237 ? 120.518 158.691 158.864 1.00 114.65 ? 327 GLN B C   1 
ATOM 2224 O O   . GLN B 1 237 ? 121.341 157.775 158.954 1.00 114.65 ? 327 GLN B O   1 
ATOM 2225 C CB  . GLN B 1 237 ? 121.521 160.867 158.182 1.00 114.65 ? 327 GLN B CB  1 
ATOM 2226 C CG  . GLN B 1 237 ? 121.240 162.135 157.417 1.00 114.65 ? 327 GLN B CG  1 
ATOM 2227 C CD  . GLN B 1 237 ? 122.417 163.077 157.422 1.00 114.65 ? 327 GLN B CD  1 
ATOM 2228 O OE1 . GLN B 1 237 ? 123.116 163.208 158.424 1.00 114.65 ? 327 GLN B OE1 1 
ATOM 2229 N NE2 . GLN B 1 237 ? 122.648 163.738 156.295 1.00 114.65 ? 327 GLN B NE2 1 
ATOM 2230 N N   . SER B 1 238 ? 119.476 158.814 159.689 1.00 115.58 ? 328 SER B N   1 
ATOM 2231 C CA  . SER B 1 238 ? 119.395 158.082 160.946 1.00 115.58 ? 328 SER B CA  1 
ATOM 2232 C C   . SER B 1 238 ? 119.430 156.576 160.754 1.00 115.58 ? 328 SER B C   1 
ATOM 2233 O O   . SER B 1 238 ? 119.773 155.848 161.690 1.00 115.58 ? 328 SER B O   1 
ATOM 2234 C CB  . SER B 1 238 ? 118.117 158.464 161.683 1.00 115.58 ? 328 SER B CB  1 
ATOM 2235 O OG  . SER B 1 238 ? 117.044 157.649 161.248 1.00 115.58 ? 328 SER B OG  1 
ATOM 2236 N N   . LEU B 1 239 ? 119.058 156.082 159.581 1.00 106.50 ? 329 LEU B N   1 
ATOM 2237 C CA  . LEU B 1 239 ? 118.965 154.638 159.437 1.00 106.50 ? 329 LEU B CA  1 
ATOM 2238 C C   . LEU B 1 239 ? 120.121 154.068 158.632 1.00 106.50 ? 329 LEU B C   1 
ATOM 2239 O O   . LEU B 1 239 ? 120.266 152.843 158.545 1.00 106.50 ? 329 LEU B O   1 
ATOM 2240 C CB  . LEU B 1 239 ? 117.627 154.271 158.809 1.00 106.50 ? 329 LEU B CB  1 
ATOM 2241 C CG  . LEU B 1 239 ? 116.427 154.589 159.703 1.00 106.50 ? 329 LEU B CG  1 
ATOM 2242 C CD1 . LEU B 1 239 ? 115.248 153.715 159.324 1.00 106.50 ? 329 LEU B CD1 1 
ATOM 2243 C CD2 . LEU B 1 239 ? 116.773 154.412 161.176 1.00 106.50 ? 329 LEU B CD2 1 
ATOM 2244 N N   . TRP B 1 240 ? 120.943 154.931 158.036 1.00 102.60 ? 330 TRP B N   1 
ATOM 2245 C CA  . TRP B 1 240 ? 122.076 154.449 157.258 1.00 102.60 ? 330 TRP B CA  1 
ATOM 2246 C C   . TRP B 1 240 ? 122.928 153.495 158.074 1.00 102.60 ? 330 TRP B C   1 
ATOM 2247 O O   . TRP B 1 240 ? 123.166 152.355 157.666 1.00 102.60 ? 330 TRP B O   1 
ATOM 2248 C CB  . TRP B 1 240 ? 122.928 155.618 156.779 1.00 102.60 ? 330 TRP B CB  1 
ATOM 2249 C CG  . TRP B 1 240 ? 122.225 156.538 155.880 1.00 102.60 ? 330 TRP B CG  1 
ATOM 2250 C CD1 . TRP B 1 240 ? 121.122 156.269 155.140 1.00 102.60 ? 330 TRP B CD1 1 
ATOM 2251 C CD2 . TRP B 1 240 ? 122.571 157.896 155.614 1.00 102.60 ? 330 TRP B CD2 1 
ATOM 2252 N NE1 . TRP B 1 240 ? 120.751 157.378 154.428 1.00 102.60 ? 330 TRP B NE1 1 
ATOM 2253 C CE2 . TRP B 1 240 ? 121.628 158.392 154.701 1.00 102.60 ? 330 TRP B CE2 1 
ATOM 2254 C CE3 . TRP B 1 240 ? 123.585 158.741 156.063 1.00 102.60 ? 330 TRP B CE3 1 
ATOM 2255 C CZ2 . TRP B 1 240 ? 121.667 159.697 154.224 1.00 102.60 ? 330 TRP B CZ2 1 
ATOM 2256 C CZ3 . TRP B 1 240 ? 123.624 160.035 155.588 1.00 102.60 ? 330 TRP B CZ3 1 
ATOM 2257 C CH2 . TRP B 1 240 ? 122.672 160.501 154.679 1.00 102.60 ? 330 TRP B CH2 1 
ATOM 2258 N N   . LYS B 1 241 ? 123.420 153.961 159.216 1.00 98.74  ? 331 LYS B N   1 
ATOM 2259 C CA  . LYS B 1 241 ? 124.379 153.177 159.974 1.00 98.74  ? 331 LYS B CA  1 
ATOM 2260 C C   . LYS B 1 241 ? 123.786 151.845 160.386 1.00 98.74  ? 331 LYS B C   1 
ATOM 2261 O O   . LYS B 1 241 ? 124.413 150.792 160.215 1.00 98.74  ? 331 LYS B O   1 
ATOM 2262 C CB  . LYS B 1 241 ? 124.837 153.967 161.191 1.00 98.74  ? 331 LYS B CB  1 
ATOM 2263 C CG  . LYS B 1 241 ? 125.501 155.281 160.849 1.00 98.74  ? 331 LYS B CG  1 
ATOM 2264 C CD  . LYS B 1 241 ? 126.151 155.890 162.072 1.00 98.74  ? 331 LYS B CD  1 
ATOM 2265 C CE  . LYS B 1 241 ? 127.052 157.052 161.713 1.00 98.74  ? 331 LYS B CE  1 
ATOM 2266 N NZ  . LYS B 1 241 ? 127.959 157.403 162.842 1.00 98.74  ? 331 LYS B NZ  1 
ATOM 2267 N N   . ARG B 1 242 ? 122.572 151.866 160.917 1.00 90.71  ? 332 ARG B N   1 
ATOM 2268 C CA  . ARG B 1 242 ? 121.968 150.612 161.320 1.00 90.71  ? 332 ARG B CA  1 
ATOM 2269 C C   . ARG B 1 242 ? 121.794 149.679 160.141 1.00 90.71  ? 332 ARG B C   1 
ATOM 2270 O O   . ARG B 1 242 ? 122.085 148.483 160.257 1.00 90.71  ? 332 ARG B O   1 
ATOM 2271 C CB  . ARG B 1 242 ? 120.625 150.859 161.998 1.00 90.71  ? 332 ARG B CB  1 
ATOM 2272 C CG  . ARG B 1 242 ? 120.728 151.005 163.501 1.00 90.71  ? 332 ARG B CG  1 
ATOM 2273 C CD  . ARG B 1 242 ? 120.965 149.667 164.169 1.00 90.71  ? 332 ARG B CD  1 
ATOM 2274 N NE  . ARG B 1 242 ? 121.501 149.828 165.514 1.00 90.71  ? 332 ARG B NE  1 
ATOM 2275 C CZ  . ARG B 1 242 ? 121.543 148.862 166.423 1.00 90.71  ? 332 ARG B CZ  1 
ATOM 2276 N NH1 . ARG B 1 242 ? 121.077 147.656 166.139 1.00 90.71  ? 332 ARG B NH1 1 
ATOM 2277 N NH2 . ARG B 1 242 ? 122.052 149.104 167.620 1.00 90.71  ? 332 ARG B NH2 1 
ATOM 2278 N N   . GLN B 1 243 ? 121.347 150.190 158.998 1.00 81.90  ? 333 GLN B N   1 
ATOM 2279 C CA  . GLN B 1 243 ? 121.066 149.283 157.901 1.00 81.90  ? 333 GLN B CA  1 
ATOM 2280 C C   . GLN B 1 243 ? 122.356 148.739 157.314 1.00 81.90  ? 333 GLN B C   1 
ATOM 2281 O O   . GLN B 1 243 ? 122.419 147.582 156.893 1.00 81.90  ? 333 GLN B O   1 
ATOM 2282 C CB  . GLN B 1 243 ? 120.212 149.981 156.848 1.00 81.90  ? 333 GLN B CB  1 
ATOM 2283 C CG  . GLN B 1 243 ? 119.467 149.009 155.959 1.00 81.90  ? 333 GLN B CG  1 
ATOM 2284 C CD  . GLN B 1 243 ? 118.213 149.605 155.363 1.00 81.90  ? 333 GLN B CD  1 
ATOM 2285 O OE1 . GLN B 1 243 ? 117.890 150.766 155.601 1.00 81.90  ? 333 GLN B OE1 1 
ATOM 2286 N NE2 . GLN B 1 243 ? 117.490 148.806 154.590 1.00 81.90  ? 333 GLN B NE2 1 
ATOM 2287 N N   . LEU B 1 244 ? 123.418 149.537 157.336 1.00 70.40  ? 334 LEU B N   1 
ATOM 2288 C CA  . LEU B 1 244 ? 124.706 149.036 156.884 1.00 70.40  ? 334 LEU B CA  1 
ATOM 2289 C C   . LEU B 1 244 ? 125.202 147.936 157.801 1.00 70.40  ? 334 LEU B C   1 
ATOM 2290 O O   . LEU B 1 244 ? 125.689 146.898 157.338 1.00 70.40  ? 334 LEU B O   1 
ATOM 2291 C CB  . LEU B 1 244 ? 125.716 150.169 156.833 1.00 70.40  ? 334 LEU B CB  1 
ATOM 2292 C CG  . LEU B 1 244 ? 127.121 149.690 156.540 1.00 70.40  ? 334 LEU B CG  1 
ATOM 2293 C CD1 . LEU B 1 244 ? 127.104 149.004 155.215 1.00 70.40  ? 334 LEU B CD1 1 
ATOM 2294 C CD2 . LEU B 1 244 ? 128.043 150.869 156.499 1.00 70.40  ? 334 LEU B CD2 1 
ATOM 2295 N N   . ALA B 1 245 ? 125.093 148.155 159.107 1.00 70.81  ? 335 ALA B N   1 
ATOM 2296 C CA  . ALA B 1 245 ? 125.412 147.097 160.049 1.00 70.81  ? 335 ALA B CA  1 
ATOM 2297 C C   . ALA B 1 245 ? 124.658 145.830 159.695 1.00 70.81  ? 335 ALA B C   1 
ATOM 2298 O O   . ALA B 1 245 ? 125.261 144.776 159.466 1.00 70.81  ? 335 ALA B O   1 
ATOM 2299 C CB  . ALA B 1 245 ? 125.077 147.545 161.468 1.00 70.81  ? 335 ALA B CB  1 
ATOM 2300 N N   . LYS B 1 246 ? 123.334 145.928 159.601 1.00 72.83  ? 336 LYS B N   1 
ATOM 2301 C CA  . LYS B 1 246 ? 122.529 144.761 159.277 1.00 72.83  ? 336 LYS B CA  1 
ATOM 2302 C C   . LYS B 1 246 ? 122.885 144.182 157.922 1.00 72.83  ? 336 LYS B C   1 
ATOM 2303 O O   . LYS B 1 246 ? 122.556 143.026 157.645 1.00 72.83  ? 336 LYS B O   1 
ATOM 2304 C CB  . LYS B 1 246 ? 121.046 145.109 159.313 1.00 72.83  ? 336 LYS B CB  1 
ATOM 2305 C CG  . LYS B 1 246 ? 120.494 145.273 160.707 1.00 72.83  ? 336 LYS B CG  1 
ATOM 2306 C CD  . LYS B 1 246 ? 119.007 145.007 160.732 1.00 72.83  ? 336 LYS B CD  1 
ATOM 2307 C CE  . LYS B 1 246 ? 118.418 145.362 162.080 1.00 72.83  ? 336 LYS B CE  1 
ATOM 2308 N NZ  . LYS B 1 246 ? 117.068 144.767 162.263 1.00 72.83  ? 336 LYS B NZ  1 
ATOM 2309 N N   . ALA B 1 247 ? 123.540 144.956 157.071 1.00 65.53  ? 337 ALA B N   1 
ATOM 2310 C CA  . ALA B 1 247 ? 123.958 144.403 155.797 1.00 65.53  ? 337 ALA B CA  1 
ATOM 2311 C C   . ALA B 1 247 ? 125.221 143.572 155.945 1.00 65.53  ? 337 ALA B C   1 
ATOM 2312 O O   . ALA B 1 247 ? 125.300 142.466 155.409 1.00 65.53  ? 337 ALA B O   1 
ATOM 2313 C CB  . ALA B 1 247 ? 124.160 145.520 154.784 1.00 65.53  ? 337 ALA B CB  1 
ATOM 2314 N N   . VAL B 1 248 ? 126.230 144.079 156.650 1.00 65.28  ? 338 VAL B N   1 
ATOM 2315 C CA  . VAL B 1 248 ? 127.452 143.293 156.787 1.00 65.28  ? 338 VAL B CA  1 
ATOM 2316 C C   . VAL B 1 248 ? 127.308 142.167 157.789 1.00 65.28  ? 338 VAL B C   1 
ATOM 2317 O O   . VAL B 1 248 ? 127.912 141.106 157.595 1.00 65.28  ? 338 VAL B O   1 
ATOM 2318 C CB  . VAL B 1 248 ? 128.674 144.125 157.194 1.00 65.28  ? 338 VAL B CB  1 
ATOM 2319 C CG1 . VAL B 1 248 ? 129.056 145.053 156.080 1.00 65.28  ? 338 VAL B CG1 1 
ATOM 2320 C CG2 . VAL B 1 248 ? 128.391 144.884 158.473 1.00 65.28  ? 338 VAL B CG2 1 
ATOM 2321 N N   . GLY B 1 249 ? 126.542 142.360 158.847 1.00 71.75  ? 339 GLY B N   1 
ATOM 2322 C CA  . GLY B 1 249 ? 126.307 141.324 159.818 1.00 71.75  ? 339 GLY B CA  1 
ATOM 2323 C C   . GLY B 1 249 ? 126.543 141.686 161.262 1.00 71.75  ? 339 GLY B C   1 
ATOM 2324 O O   . GLY B 1 249 ? 126.465 140.799 162.117 1.00 71.75  ? 339 GLY B O   1 
ATOM 2325 N N   . LEU B 1 250 ? 126.790 142.950 161.569 1.00 84.24  ? 340 LEU B N   1 
ATOM 2326 C CA  . LEU B 1 250 ? 127.024 143.348 162.951 1.00 84.24  ? 340 LEU B CA  1 
ATOM 2327 C C   . LEU B 1 250 ? 125.711 143.169 163.694 1.00 84.24  ? 340 LEU B C   1 
ATOM 2328 O O   . LEU B 1 250 ? 124.819 144.013 163.644 1.00 84.24  ? 340 LEU B O   1 
ATOM 2329 C CB  . LEU B 1 250 ? 127.523 144.779 163.019 1.00 84.24  ? 340 LEU B CB  1 
ATOM 2330 C CG  . LEU B 1 250 ? 129.022 144.871 162.792 1.00 84.24  ? 340 LEU B CG  1 
ATOM 2331 C CD1 . LEU B 1 250 ? 129.501 146.277 163.046 1.00 84.24  ? 340 LEU B CD1 1 
ATOM 2332 C CD2 . LEU B 1 250 ? 129.726 143.900 163.697 1.00 84.24  ? 340 LEU B CD2 1 
ATOM 2333 N N   . THR B 1 251 ? 125.590 142.045 164.392 1.00 86.69  ? 341 THR B N   1 
ATOM 2334 C CA  . THR B 1 251 ? 124.292 141.593 164.864 1.00 86.69  ? 341 THR B CA  1 
ATOM 2335 C C   . THR B 1 251 ? 124.246 141.313 166.362 1.00 86.69  ? 341 THR B C   1 
ATOM 2336 O O   . THR B 1 251 ? 123.153 141.123 166.902 1.00 86.69  ? 341 THR B O   1 
ATOM 2337 C CB  . THR B 1 251 ? 123.889 140.332 164.086 1.00 86.69  ? 341 THR B CB  1 
ATOM 2338 O OG1 . THR B 1 251 ? 124.055 140.579 162.687 1.00 86.69  ? 341 THR B OG1 1 
ATOM 2339 C CG2 . THR B 1 251 ? 122.432 139.992 164.316 1.00 86.69  ? 341 THR B CG2 1 
ATOM 2340 N N   . ALA B 1 252 ? 125.381 141.299 167.054 1.00 101.63 ? 342 ALA B N   1 
ATOM 2341 C CA  . ALA B 1 252 ? 125.415 140.850 168.436 1.00 101.63 ? 342 ALA B CA  1 
ATOM 2342 C C   . ALA B 1 252 ? 124.558 141.737 169.333 1.00 101.63 ? 342 ALA B C   1 
ATOM 2343 O O   . ALA B 1 252 ? 124.099 142.814 168.947 1.00 101.63 ? 342 ALA B O   1 
ATOM 2344 C CB  . ALA B 1 252 ? 126.847 140.827 168.959 1.00 101.63 ? 342 ALA B CB  1 
ATOM 2345 N N   . ALA B 1 253 ? 124.345 141.258 170.558 1.00 111.47 ? 343 ALA B N   1 
ATOM 2346 C CA  . ALA B 1 253 ? 123.577 142.025 171.529 1.00 111.47 ? 343 ALA B CA  1 
ATOM 2347 C C   . ALA B 1 253 ? 124.203 143.388 171.776 1.00 111.47 ? 343 ALA B C   1 
ATOM 2348 O O   . ALA B 1 253 ? 123.494 144.403 171.818 1.00 111.47 ? 343 ALA B O   1 
ATOM 2349 C CB  . ALA B 1 253 ? 123.461 141.247 172.838 1.00 111.47 ? 343 ALA B CB  1 
ATOM 2350 N N   . TYR B 1 254 ? 125.523 143.437 171.941 1.00 115.66 ? 344 TYR B N   1 
ATOM 2351 C CA  . TYR B 1 254 ? 126.181 144.731 172.044 1.00 115.66 ? 344 TYR B CA  1 
ATOM 2352 C C   . TYR B 1 254 ? 125.988 145.529 170.764 1.00 115.66 ? 344 TYR B C   1 
ATOM 2353 O O   . TYR B 1 254 ? 125.859 146.757 170.800 1.00 115.66 ? 344 TYR B O   1 
ATOM 2354 C CB  . TYR B 1 254 ? 127.666 144.564 172.346 1.00 115.66 ? 344 TYR B CB  1 
ATOM 2355 C CG  . TYR B 1 254 ? 128.433 145.826 172.051 1.00 115.66 ? 344 TYR B CG  1 
ATOM 2356 C CD1 . TYR B 1 254 ? 129.263 145.917 170.945 1.00 115.66 ? 344 TYR B CD1 1 
ATOM 2357 C CD2 . TYR B 1 254 ? 128.296 146.943 172.860 1.00 115.66 ? 344 TYR B CD2 1 
ATOM 2358 C CE1 . TYR B 1 254 ? 129.953 147.079 170.668 1.00 115.66 ? 344 TYR B CE1 1 
ATOM 2359 C CE2 . TYR B 1 254 ? 128.980 148.107 172.590 1.00 115.66 ? 344 TYR B CE2 1 
ATOM 2360 C CZ  . TYR B 1 254 ? 129.808 148.169 171.494 1.00 115.66 ? 344 TYR B CZ  1 
ATOM 2361 O OH  . TYR B 1 254 ? 130.493 149.329 171.223 1.00 115.66 ? 344 TYR B OH  1 
ATOM 2362 N N   . ASP B 1 255 ? 125.962 144.841 169.622 1.00 106.91 ? 345 ASP B N   1 
ATOM 2363 C CA  . ASP B 1 255 ? 125.734 145.529 168.357 1.00 106.91 ? 345 ASP B CA  1 
ATOM 2364 C C   . ASP B 1 255 ? 124.371 146.203 168.345 1.00 106.91 ? 345 ASP B C   1 
ATOM 2365 O O   . ASP B 1 255 ? 124.169 147.206 167.652 1.00 106.91 ? 345 ASP B O   1 
ATOM 2366 C CB  . ASP B 1 255 ? 125.849 144.548 167.198 1.00 106.91 ? 345 ASP B CB  1 
ATOM 2367 C CG  . ASP B 1 255 ? 127.208 143.906 167.120 1.00 106.91 ? 345 ASP B CG  1 
ATOM 2368 O OD1 . ASP B 1 255 ? 128.178 144.508 167.622 1.00 106.91 ? 345 ASP B OD1 1 
ATOM 2369 O OD2 . ASP B 1 255 ? 127.305 142.803 166.544 1.00 106.91 ? 345 ASP B OD2 1 
ATOM 2370 N N   . ALA B 1 256 ? 123.419 145.663 169.104 1.00 113.53 ? 346 ALA B N   1 
ATOM 2371 C CA  . ALA B 1 256 ? 122.135 146.332 169.242 1.00 113.53 ? 346 ALA B CA  1 
ATOM 2372 C C   . ALA B 1 256 ? 122.183 147.450 170.271 1.00 113.53 ? 346 ALA B C   1 
ATOM 2373 O O   . ALA B 1 256 ? 121.625 148.524 170.027 1.00 113.53 ? 346 ALA B O   1 
ATOM 2374 C CB  . ALA B 1 256 ? 121.055 145.325 169.609 1.00 50.00  ? 346 ALA B CB  1 
ATOM 2375 N N   . SER B 1 257 ? 122.856 147.233 171.400 1.00 118.33 ? 347 SER B N   1 
ATOM 2376 C CA  . SER B 1 257 ? 122.833 148.207 172.483 1.00 118.33 ? 347 SER B CA  1 
ATOM 2377 C C   . SER B 1 257 ? 123.662 149.449 172.195 1.00 118.33 ? 347 SER B C   1 
ATOM 2378 O O   . SER B 1 257 ? 123.436 150.483 172.831 1.00 118.33 ? 347 SER B O   1 
ATOM 2379 C CB  . SER B 1 257 ? 123.327 147.561 173.776 1.00 118.33 ? 347 SER B CB  1 
ATOM 2380 O OG  . SER B 1 257 ? 124.505 146.814 173.545 1.00 118.33 ? 347 SER B OG  1 
ATOM 2381 N N   . TYR B 1 258 ? 124.606 149.383 171.266 1.00 121.67 ? 348 TYR B N   1 
ATOM 2382 C CA  . TYR B 1 258 ? 125.437 150.538 170.962 1.00 121.67 ? 348 TYR B CA  1 
ATOM 2383 C C   . TYR B 1 258 ? 124.607 151.595 170.250 1.00 121.67 ? 348 TYR B C   1 
ATOM 2384 O O   . TYR B 1 258 ? 123.675 151.268 169.510 1.00 121.67 ? 348 TYR B O   1 
ATOM 2385 C CB  . TYR B 1 258 ? 126.624 150.117 170.103 1.00 121.67 ? 348 TYR B CB  1 
ATOM 2386 C CG  . TYR B 1 258 ? 127.472 151.261 169.607 1.00 121.67 ? 348 TYR B CG  1 
ATOM 2387 C CD1 . TYR B 1 258 ? 127.196 151.885 168.400 1.00 121.67 ? 348 TYR B CD1 1 
ATOM 2388 C CD2 . TYR B 1 258 ? 128.554 151.711 170.344 1.00 121.67 ? 348 TYR B CD2 1 
ATOM 2389 C CE1 . TYR B 1 258 ? 127.975 152.916 167.941 1.00 121.67 ? 348 TYR B CE1 1 
ATOM 2390 C CE2 . TYR B 1 258 ? 129.335 152.748 169.896 1.00 121.67 ? 348 TYR B CE2 1 
ATOM 2391 C CZ  . TYR B 1 258 ? 129.040 153.349 168.695 1.00 121.67 ? 348 TYR B CZ  1 
ATOM 2392 O OH  . TYR B 1 258 ? 129.820 154.386 168.243 1.00 121.67 ? 348 TYR B OH  1 
ATOM 2393 N N   . THR B 1 259 ? 124.940 152.863 170.478 1.00 121.90 ? 349 THR B N   1 
ATOM 2394 C CA  . THR B 1 259 ? 124.233 153.973 169.844 1.00 121.90 ? 349 THR B CA  1 
ATOM 2395 C C   . THR B 1 259 ? 125.158 154.641 168.836 1.00 121.90 ? 349 THR B C   1 
ATOM 2396 O O   . THR B 1 259 ? 126.291 155.013 169.141 1.00 121.90 ? 349 THR B O   1 
ATOM 2397 C CB  . THR B 1 259 ? 123.725 154.957 170.889 1.00 121.90 ? 349 THR B CB  1 
ATOM 2398 O OG1 . THR B 1 259 ? 123.071 156.051 170.234 1.00 121.90 ? 349 THR B OG1 1 
ATOM 2399 C CG2 . THR B 1 259 ? 124.862 155.478 171.762 1.00 121.90 ? 349 THR B CG2 1 
ATOM 2400 N N   . PHE B 1 260 ? 124.664 154.786 167.611 1.00 117.79 ? 350 PHE B N   1 
ATOM 2401 C CA  . PHE B 1 260 ? 125.437 155.441 166.568 1.00 117.79 ? 350 PHE B CA  1 
ATOM 2402 C C   . PHE B 1 260 ? 125.599 156.924 166.868 1.00 117.79 ? 350 PHE B C   1 
ATOM 2403 O O   . PHE B 1 260 ? 124.765 157.535 167.539 1.00 117.79 ? 350 PHE B O   1 
ATOM 2404 C CB  . PHE B 1 260 ? 124.755 155.259 165.216 1.00 117.79 ? 350 PHE B CB  1 
ATOM 2405 C CG  . PHE B 1 260 ? 124.924 153.889 164.631 1.00 117.79 ? 350 PHE B CG  1 
ATOM 2406 C CD1 . PHE B 1 260 ? 126.184 153.374 164.395 1.00 117.79 ? 350 PHE B CD1 1 
ATOM 2407 C CD2 . PHE B 1 260 ? 123.821 153.116 164.317 1.00 117.79 ? 350 PHE B CD2 1 
ATOM 2408 C CE1 . PHE B 1 260 ? 126.338 152.116 163.854 1.00 117.79 ? 350 PHE B CE1 1 
ATOM 2409 C CE2 . PHE B 1 260 ? 123.974 151.859 163.778 1.00 117.79 ? 350 PHE B CE2 1 
ATOM 2410 C CZ  . PHE B 1 260 ? 125.230 151.360 163.544 1.00 117.79 ? 350 PHE B CZ  1 
ATOM 2411 N N   . SER B 1 261 ? 126.684 157.498 166.370 1.00 123.60 ? 351 SER B N   1 
ATOM 2412 C CA  . SER B 1 261 ? 126.902 158.924 166.533 1.00 123.60 ? 351 SER B CA  1 
ATOM 2413 C C   . SER B 1 261 ? 126.412 159.668 165.295 1.00 123.60 ? 351 SER B C   1 
ATOM 2414 O O   . SER B 1 261 ? 126.311 159.077 164.215 1.00 123.60 ? 351 SER B O   1 
ATOM 2415 C CB  . SER B 1 261 ? 128.382 159.215 166.766 1.00 123.60 ? 351 SER B CB  1 
ATOM 2416 O OG  . SER B 1 261 ? 129.188 158.517 165.836 1.00 123.60 ? 351 SER B OG  1 
ATOM 2417 N N   . PRO B 1 262 ? 126.086 160.953 165.412 1.00 128.78 ? 352 PRO B N   1 
ATOM 2418 C CA  . PRO B 1 262 ? 125.709 161.732 164.231 1.00 128.78 ? 352 PRO B CA  1 
ATOM 2419 C C   . PRO B 1 262 ? 126.935 162.183 163.453 1.00 128.78 ? 352 PRO B C   1 
ATOM 2420 O O   . PRO B 1 262 ? 128.070 162.132 163.929 1.00 128.78 ? 352 PRO B O   1 
ATOM 2421 C CB  . PRO B 1 262 ? 124.951 162.920 164.820 1.00 128.78 ? 352 PRO B CB  1 
ATOM 2422 C CG  . PRO B 1 262 ? 125.573 163.107 166.158 1.00 128.78 ? 352 PRO B CG  1 
ATOM 2423 C CD  . PRO B 1 262 ? 125.928 161.728 166.656 1.00 128.78 ? 352 PRO B CD  1 
ATOM 2424 N N   . PHE B 1 263 ? 126.690 162.642 162.231 1.00 130.23 ? 353 PHE B N   1 
ATOM 2425 C CA  . PHE B 1 263 ? 127.776 163.095 161.379 1.00 130.23 ? 353 PHE B CA  1 
ATOM 2426 C C   . PHE B 1 263 ? 128.239 164.490 161.778 1.00 130.23 ? 353 PHE B C   1 
ATOM 2427 O O   . PHE B 1 263 ? 127.667 165.142 162.654 1.00 130.23 ? 353 PHE B O   1 
ATOM 2428 C CB  . PHE B 1 263 ? 127.348 163.096 159.917 1.00 130.23 ? 353 PHE B CB  1 
ATOM 2429 C CG  . PHE B 1 263 ? 127.171 161.730 159.350 1.00 130.23 ? 353 PHE B CG  1 
ATOM 2430 C CD1 . PHE B 1 263 ? 128.207 160.818 159.391 1.00 130.23 ? 353 PHE B CD1 1 
ATOM 2431 C CD2 . PHE B 1 263 ? 125.971 161.355 158.782 1.00 130.23 ? 353 PHE B CD2 1 
ATOM 2432 C CE1 . PHE B 1 263 ? 128.050 159.556 158.873 1.00 130.23 ? 353 PHE B CE1 1 
ATOM 2433 C CE2 . PHE B 1 263 ? 125.807 160.094 158.262 1.00 130.23 ? 353 PHE B CE2 1 
ATOM 2434 C CZ  . PHE B 1 263 ? 126.848 159.193 158.308 1.00 130.23 ? 353 PHE B CZ  1 
ATOM 2435 N N   . SER B 1 264 ? 129.292 164.947 161.109 1.00 142.62 ? 354 SER B N   1 
ATOM 2436 C CA  . SER B 1 264 ? 129.855 166.267 161.363 1.00 142.62 ? 354 SER B CA  1 
ATOM 2437 C C   . SER B 1 264 ? 129.021 167.360 160.706 1.00 142.62 ? 354 SER B C   1 
ATOM 2438 O O   . SER B 1 264 ? 129.557 168.363 160.237 1.00 142.62 ? 354 SER B O   1 
ATOM 2439 C CB  . SER B 1 264 ? 131.298 166.337 160.860 1.00 142.62 ? 354 SER B CB  1 
ATOM 2440 O OG  . SER B 1 264 ? 131.340 166.730 159.499 1.00 142.62 ? 354 SER B OG  1 
ATOM 2441 N N   . MET C 1 118 ? 121.354 131.972 69.984  1.00 181.04 ? 208 MET C N   1 
ATOM 2442 C CA  . MET C 1 118 ? 122.549 132.554 70.582  1.00 181.04 ? 208 MET C CA  1 
ATOM 2443 C C   . MET C 1 118 ? 122.199 133.797 71.394  1.00 181.04 ? 208 MET C C   1 
ATOM 2444 O O   . MET C 1 118 ? 122.820 134.076 72.428  1.00 181.04 ? 208 MET C O   1 
ATOM 2445 C CB  . MET C 1 118 ? 123.577 132.899 69.504  1.00 50.00  ? 208 MET C CB  1 
ATOM 2446 C CG  . MET C 1 118 ? 124.154 131.691 68.785  1.00 50.00  ? 208 MET C CG  1 
ATOM 2447 S SD  . MET C 1 118 ? 124.999 130.555 69.900  1.00 50.00  ? 208 MET C SD  1 
ATOM 2448 C CE  . MET C 1 118 ? 126.398 131.554 70.404  1.00 50.00  ? 208 MET C CE  1 
ATOM 2449 N N   . GLY C 1 119 ? 121.189 134.548 70.944  1.00 178.31 ? 209 GLY C N   1 
ATOM 2450 C CA  . GLY C 1 119 ? 120.632 135.600 71.789  1.00 178.31 ? 209 GLY C CA  1 
ATOM 2451 C C   . GLY C 1 119 ? 120.275 135.042 73.155  1.00 178.31 ? 209 GLY C C   1 
ATOM 2452 O O   . GLY C 1 119 ? 120.843 135.448 74.179  1.00 178.31 ? 209 GLY C O   1 
ATOM 2453 N N   . GLU C 1 120 ? 119.355 134.075 73.175  1.00 176.35 ? 210 GLU C N   1 
ATOM 2454 C CA  . GLU C 1 120 ? 118.925 133.463 74.423  1.00 176.35 ? 210 GLU C CA  1 
ATOM 2455 C C   . GLU C 1 120 ? 120.111 132.988 75.243  1.00 176.35 ? 210 GLU C C   1 
ATOM 2456 O O   . GLU C 1 120 ? 120.110 133.128 76.468  1.00 176.35 ? 210 GLU C O   1 
ATOM 2457 C CB  . GLU C 1 120 ? 117.977 132.295 74.146  1.00 50.00  ? 210 GLU C CB  1 
ATOM 2458 C CG  . GLU C 1 120 ? 116.641 132.708 73.547  1.00 50.00  ? 210 GLU C CG  1 
ATOM 2459 C CD  . GLU C 1 120 ? 115.759 131.518 73.219  1.00 50.00  ? 210 GLU C CD  1 
ATOM 2460 O OE1 . GLU C 1 120 ? 116.254 130.374 73.280  1.00 50.00  ? 210 GLU C OE1 1 
ATOM 2461 O OE2 . GLU C 1 120 ? 114.570 131.728 72.899  1.00 50.00  ? 210 GLU C OE2 1 
ATOM 2462 N N   . TRP C 1 121 ? 121.120 132.419 74.584  1.00 166.64 ? 211 TRP C N   1 
ATOM 2463 C CA  . TRP C 1 121 ? 122.356 132.077 75.274  1.00 166.64 ? 211 TRP C CA  1 
ATOM 2464 C C   . TRP C 1 121 ? 122.912 133.284 76.015  1.00 166.64 ? 211 TRP C C   1 
ATOM 2465 O O   . TRP C 1 121 ? 123.281 133.186 77.190  1.00 166.64 ? 211 TRP C O   1 
ATOM 2466 C CB  . TRP C 1 121 ? 123.394 131.541 74.286  1.00 50.00  ? 211 TRP C CB  1 
ATOM 2467 C CG  . TRP C 1 121 ? 123.047 130.197 73.722  1.00 50.00  ? 211 TRP C CG  1 
ATOM 2468 C CD1 . TRP C 1 121 ? 122.405 129.939 72.545  1.00 50.00  ? 211 TRP C CD1 1 
ATOM 2469 C CD2 . TRP C 1 121 ? 123.323 128.921 74.314  1.00 50.00  ? 211 TRP C CD2 1 
ATOM 2470 N NE1 . TRP C 1 121 ? 122.264 128.584 72.369  1.00 50.00  ? 211 TRP C NE1 1 
ATOM 2471 C CE2 . TRP C 1 121 ? 122.820 127.936 73.439  1.00 50.00  ? 211 TRP C CE2 1 
ATOM 2472 C CE3 . TRP C 1 121 ? 123.945 128.508 75.497  1.00 50.00  ? 211 TRP C CE3 1 
ATOM 2473 C CZ2 . TRP C 1 121 ? 122.919 126.572 73.710  1.00 50.00  ? 211 TRP C CZ2 1 
ATOM 2474 C CZ3 . TRP C 1 121 ? 124.042 127.155 75.762  1.00 50.00  ? 211 TRP C CZ3 1 
ATOM 2475 C CH2 . TRP C 1 121 ? 123.533 126.204 74.874  1.00 50.00  ? 211 TRP C CH2 1 
ATOM 2476 N N   . LYS C 1 122 ? 122.963 134.431 75.346  1.00 160.82 ? 212 LYS C N   1 
ATOM 2477 C CA  . LYS C 1 122 ? 123.513 135.626 75.969  1.00 160.82 ? 212 LYS C CA  1 
ATOM 2478 C C   . LYS C 1 122 ? 122.678 136.107 77.147  1.00 160.82 ? 212 LYS C C   1 
ATOM 2479 O O   . LYS C 1 122 ? 123.236 136.381 78.219  1.00 160.82 ? 212 LYS C O   1 
ATOM 2480 C CB  . LYS C 1 122 ? 123.641 136.746 74.936  1.00 50.00  ? 212 LYS C CB  1 
ATOM 2481 C CG  . LYS C 1 122 ? 124.662 136.471 73.843  1.00 50.00  ? 212 LYS C CG  1 
ATOM 2482 C CD  . LYS C 1 122 ? 124.720 137.610 72.840  1.00 50.00  ? 212 LYS C CD  1 
ATOM 2483 C CE  . LYS C 1 122 ? 125.757 137.345 71.761  1.00 50.00  ? 212 LYS C CE  1 
ATOM 2484 N NZ  . LYS C 1 122 ? 125.807 138.443 70.757  1.00 50.00  ? 212 LYS C NZ  1 
ATOM 2485 N N   . LYS C 1 123 ? 121.363 136.221 76.972  1.00 159.47 ? 213 LYS C N   1 
ATOM 2486 C CA  . LYS C 1 123 ? 120.553 136.663 78.104  1.00 159.47 ? 213 LYS C CA  1 
ATOM 2487 C C   . LYS C 1 123 ? 120.624 135.659 79.244  1.00 159.47 ? 213 LYS C C   1 
ATOM 2488 O O   . LYS C 1 123 ? 120.568 136.040 80.421  1.00 159.47 ? 213 LYS C O   1 
ATOM 2489 C CB  . LYS C 1 123 ? 119.100 136.873 77.676  1.00 50.00  ? 213 LYS C CB  1 
ATOM 2490 C CG  . LYS C 1 123 ? 118.897 138.030 76.710  1.00 50.00  ? 213 LYS C CG  1 
ATOM 2491 C CD  . LYS C 1 123 ? 117.439 138.167 76.308  1.00 50.00  ? 213 LYS C CD  1 
ATOM 2492 C CE  . LYS C 1 123 ? 117.233 139.338 75.362  1.00 50.00  ? 213 LYS C CE  1 
ATOM 2493 N NZ  . LYS C 1 123 ? 115.811 139.468 74.940  1.00 50.00  ? 213 LYS C NZ  1 
ATOM 2494 N N   . ALA C 1 124 ? 120.663 134.394 78.866  1.00 159.46 ? 214 ALA C N   1 
ATOM 2495 C CA  . ALA C 1 124 ? 120.737 133.369 79.859  1.00 159.46 ? 214 ALA C CA  1 
ATOM 2496 C C   . ALA C 1 124 ? 122.012 133.591 80.578  1.00 159.46 ? 214 ALA C C   1 
ATOM 2497 O O   . ALA C 1 124 ? 122.099 133.460 81.813  1.00 159.46 ? 214 ALA C O   1 
ATOM 2498 C CB  . ALA C 1 124 ? 120.668 131.980 79.244  1.00 50.00  ? 214 ALA C CB  1 
ATOM 2499 N N   . ARG C 1 125 ? 123.063 133.870 79.816  1.00 144.07 ? 215 ARG C N   1 
ATOM 2500 C CA  . ARG C 1 125 ? 124.350 134.125 80.424  1.00 144.07 ? 215 ARG C CA  1 
ATOM 2501 C C   . ARG C 1 125 ? 124.194 135.198 81.439  1.00 144.07 ? 215 ARG C C   1 
ATOM 2502 O O   . ARG C 1 125 ? 124.686 135.088 82.561  1.00 144.07 ? 215 ARG C O   1 
ATOM 2503 C CB  . ARG C 1 125 ? 125.345 134.671 79.416  1.00 50.00  ? 215 ARG C CB  1 
ATOM 2504 C CG  . ARG C 1 125 ? 125.919 133.706 78.412  1.00 50.00  ? 215 ARG C CG  1 
ATOM 2505 C CD  . ARG C 1 125 ? 126.508 134.528 77.283  1.00 50.00  ? 215 ARG C CD  1 
ATOM 2506 N NE  . ARG C 1 125 ? 127.357 135.608 77.770  1.00 50.00  ? 215 ARG C NE  1 
ATOM 2507 C CZ  . ARG C 1 125 ? 128.663 135.494 77.986  1.00 50.00  ? 215 ARG C CZ  1 
ATOM 2508 N NH1 . ARG C 1 125 ? 129.354 136.534 78.431  1.00 50.00  ? 215 ARG C NH1 1 
ATOM 2509 N NH2 . ARG C 1 125 ? 129.279 134.343 77.761  1.00 50.00  ? 215 ARG C NH2 1 
ATOM 2510 N N   . GLU C 1 126 ? 123.503 136.262 81.055  1.00 134.65 ? 216 GLU C N   1 
ATOM 2511 C CA  . GLU C 1 126 ? 123.455 137.386 81.963  1.00 134.65 ? 216 GLU C CA  1 
ATOM 2512 C C   . GLU C 1 126 ? 122.765 137.023 83.253  1.00 134.65 ? 216 GLU C C   1 
ATOM 2513 O O   . GLU C 1 126 ? 123.288 137.283 84.336  1.00 134.65 ? 216 GLU C O   1 
ATOM 2514 C CB  . GLU C 1 126 ? 122.748 138.573 81.306  1.00 50.00  ? 216 GLU C CB  1 
ATOM 2515 C CG  . GLU C 1 126 ? 123.506 139.175 80.133  1.00 50.00  ? 216 GLU C CG  1 
ATOM 2516 C CD  . GLU C 1 126 ? 122.740 140.301 79.464  1.00 50.00  ? 216 GLU C CD  1 
ATOM 2517 O OE1 . GLU C 1 126 ? 121.549 140.487 79.788  1.00 50.00  ? 216 GLU C OE1 1 
ATOM 2518 O OE2 . GLU C 1 126 ? 123.330 140.999 78.612  1.00 50.00  ? 216 GLU C OE2 1 
ATOM 2519 N N   . GLU C 1 127 ? 121.664 136.299 83.148  1.00 140.20 ? 217 GLU C N   1 
ATOM 2520 C CA  . GLU C 1 127 ? 120.905 135.999 84.335  1.00 140.20 ? 217 GLU C CA  1 
ATOM 2521 C C   . GLU C 1 127 ? 121.780 135.188 85.224  1.00 140.20 ? 217 GLU C C   1 
ATOM 2522 O O   . GLU C 1 127 ? 121.844 135.402 86.426  1.00 140.20 ? 217 GLU C O   1 
ATOM 2523 C CB  . GLU C 1 127 ? 119.612 135.252 84.001  1.00 50.00  ? 217 GLU C CB  1 
ATOM 2524 C CG  . GLU C 1 127 ? 118.581 136.094 83.264  1.00 50.00  ? 217 GLU C CG  1 
ATOM 2525 C CD  . GLU C 1 127 ? 117.345 135.299 82.887  1.00 50.00  ? 217 GLU C CD  1 
ATOM 2526 O OE1 . GLU C 1 127 ? 117.368 134.059 83.027  1.00 50.00  ? 217 GLU C OE1 1 
ATOM 2527 O OE2 . GLU C 1 127 ? 116.351 135.916 82.448  1.00 50.00  ? 217 GLU C OE2 1 
ATOM 2528 N N   . ASP C 1 128 ? 122.506 134.258 84.611  1.00 133.10 ? 218 ASP C N   1 
ATOM 2529 C CA  . ASP C 1 128 ? 123.435 133.441 85.367  1.00 133.10 ? 218 ASP C CA  1 
ATOM 2530 C C   . ASP C 1 128 ? 124.338 134.337 86.208  1.00 133.10 ? 218 ASP C C   1 
ATOM 2531 O O   . ASP C 1 128 ? 124.451 134.147 87.414  1.00 133.10 ? 218 ASP C O   1 
ATOM 2532 C CB  . ASP C 1 128 ? 124.277 132.577 84.434  1.00 50.00  ? 218 ASP C CB  1 
ATOM 2533 C CG  . ASP C 1 128 ? 123.436 131.651 83.586  1.00 50.00  ? 218 ASP C CG  1 
ATOM 2534 O OD1 . ASP C 1 128 ? 122.248 131.455 83.920  1.00 50.00  ? 218 ASP C OD1 1 
ATOM 2535 O OD2 . ASP C 1 128 ? 123.957 131.119 82.585  1.00 50.00  ? 218 ASP C OD2 1 
ATOM 2536 N N   . LYS C 1 129 ? 124.983 135.313 85.575  1.00 129.40 ? 219 LYS C N   1 
ATOM 2537 C CA  . LYS C 1 129 ? 125.856 136.166 86.359  1.00 129.40 ? 219 LYS C CA  1 
ATOM 2538 C C   . LYS C 1 129 ? 125.122 136.843 87.498  1.00 129.40 ? 219 LYS C C   1 
ATOM 2539 O O   . LYS C 1 129 ? 125.650 136.895 88.612  1.00 129.40 ? 219 LYS C O   1 
ATOM 2540 C CB  . LYS C 1 129 ? 126.508 137.220 85.463  1.00 50.00  ? 219 LYS C CB  1 
ATOM 2541 C CG  . LYS C 1 129 ? 127.478 136.652 84.439  1.00 50.00  ? 219 LYS C CG  1 
ATOM 2542 C CD  . LYS C 1 129 ? 128.069 137.748 83.569  1.00 50.00  ? 219 LYS C CD  1 
ATOM 2543 C CE  . LYS C 1 129 ? 129.057 137.184 82.562  1.00 50.00  ? 219 LYS C CE  1 
ATOM 2544 N NZ  . LYS C 1 129 ? 129.626 138.244 81.686  1.00 50.00  ? 219 LYS C NZ  1 
ATOM 2545 N N   . GLU C 1 130 ? 123.921 137.354 87.248  1.00 135.00 ? 220 GLU C N   1 
ATOM 2546 C CA  . GLU C 1 130 ? 123.157 137.913 88.358  1.00 135.00 ? 220 GLU C CA  1 
ATOM 2547 C C   . GLU C 1 130 ? 122.932 136.859 89.431  1.00 135.00 ? 220 GLU C C   1 
ATOM 2548 O O   . GLU C 1 130 ? 123.097 137.126 90.627  1.00 135.00 ? 220 GLU C O   1 
ATOM 2549 C CB  . GLU C 1 130 ? 121.829 138.504 87.882  1.00 135.00 ? 220 GLU C CB  1 
ATOM 2550 C CG  . GLU C 1 130 ? 121.957 139.882 87.237  1.00 135.00 ? 220 GLU C CG  1 
ATOM 2551 C CD  . GLU C 1 130 ? 122.082 139.837 85.734  1.00 135.00 ? 220 GLU C CD  1 
ATOM 2552 O OE1 . GLU C 1 130 ? 121.526 138.907 85.129  1.00 135.00 ? 220 GLU C OE1 1 
ATOM 2553 O OE2 . GLU C 1 130 ? 122.735 140.729 85.155  1.00 135.00 ? 220 GLU C OE2 1 
ATOM 2554 N N   . TRP C 1 131 ? 122.578 135.644 89.014  1.00 118.52 ? 221 TRP C N   1 
ATOM 2555 C CA  . TRP C 1 131 ? 122.463 134.543 89.955  1.00 118.52 ? 221 TRP C CA  1 
ATOM 2556 C C   . TRP C 1 131 ? 123.746 134.369 90.746  1.00 118.52 ? 221 TRP C C   1 
ATOM 2557 O O   . TRP C 1 131 ? 123.713 134.104 91.957  1.00 118.52 ? 221 TRP C O   1 
ATOM 2558 C CB  . TRP C 1 131 ? 122.120 133.263 89.203  1.00 118.52 ? 221 TRP C CB  1 
ATOM 2559 C CG  . TRP C 1 131 ? 122.167 132.073 90.059  1.00 118.52 ? 221 TRP C CG  1 
ATOM 2560 C CD1 . TRP C 1 131 ? 121.332 131.774 91.087  1.00 118.52 ? 221 TRP C CD1 1 
ATOM 2561 C CD2 . TRP C 1 131 ? 123.115 131.013 89.988  1.00 118.52 ? 221 TRP C CD2 1 
ATOM 2562 N NE1 . TRP C 1 131 ? 121.693 130.583 91.655  1.00 118.52 ? 221 TRP C NE1 1 
ATOM 2563 C CE2 . TRP C 1 131 ? 122.790 130.096 90.996  1.00 118.52 ? 221 TRP C CE2 1 
ATOM 2564 C CE3 . TRP C 1 131 ? 124.207 130.748 89.165  1.00 118.52 ? 221 TRP C CE3 1 
ATOM 2565 C CZ2 . TRP C 1 131 ? 123.518 128.937 91.207  1.00 118.52 ? 221 TRP C CZ2 1 
ATOM 2566 C CZ3 . TRP C 1 131 ? 124.923 129.593 89.371  1.00 118.52 ? 221 TRP C CZ3 1 
ATOM 2567 C CH2 . TRP C 1 131 ? 124.576 128.701 90.382  1.00 118.52 ? 221 TRP C CH2 1 
ATOM 2568 N N   . ARG C 1 132 ? 124.879 134.532 90.074  1.00 118.59 ? 222 ARG C N   1 
ATOM 2569 C CA  . ARG C 1 132 ? 126.160 134.476 90.756  1.00 118.59 ? 222 ARG C CA  1 
ATOM 2570 C C   . ARG C 1 132 ? 126.224 135.523 91.852  1.00 118.59 ? 222 ARG C C   1 
ATOM 2571 O O   . ARG C 1 132 ? 126.748 135.269 92.936  1.00 118.59 ? 222 ARG C O   1 
ATOM 2572 C CB  . ARG C 1 132 ? 127.308 134.683 89.770  1.00 118.59 ? 222 ARG C CB  1 
ATOM 2573 C CG  . ARG C 1 132 ? 127.318 133.768 88.576  1.00 118.59 ? 222 ARG C CG  1 
ATOM 2574 C CD  . ARG C 1 132 ? 128.664 133.867 87.889  1.00 118.59 ? 222 ARG C CD  1 
ATOM 2575 N NE  . ARG C 1 132 ? 128.567 133.797 86.439  1.00 118.59 ? 222 ARG C NE  1 
ATOM 2576 C CZ  . ARG C 1 132 ? 128.616 132.666 85.751  1.00 118.59 ? 222 ARG C CZ  1 
ATOM 2577 N NH1 . ARG C 1 132 ? 128.741 131.514 86.390  1.00 118.59 ? 222 ARG C NH1 1 
ATOM 2578 N NH2 . ARG C 1 132 ? 128.526 132.686 84.431  1.00 118.59 ? 222 ARG C NH2 1 
ATOM 2579 N N   . LYS C 1 133 ? 125.705 136.718 91.581  1.00 118.75 ? 223 LYS C N   1 
ATOM 2580 C CA  . LYS C 1 133 ? 125.808 137.790 92.561  1.00 118.75 ? 223 LYS C CA  1 
ATOM 2581 C C   . LYS C 1 133 ? 125.012 137.459 93.814  1.00 118.75 ? 223 LYS C C   1 
ATOM 2582 O O   . LYS C 1 133 ? 125.490 137.655 94.939  1.00 118.75 ? 223 LYS C O   1 
ATOM 2583 C CB  . LYS C 1 133 ? 125.346 139.111 91.943  1.00 118.75 ? 223 LYS C CB  1 
ATOM 2584 C CG  . LYS C 1 133 ? 126.502 139.970 91.440  1.00 118.75 ? 223 LYS C CG  1 
ATOM 2585 C CD  . LYS C 1 133 ? 126.073 141.397 91.138  1.00 118.75 ? 223 LYS C CD  1 
ATOM 2586 C CE  . LYS C 1 133 ? 127.230 142.208 90.571  1.00 118.75 ? 223 LYS C CE  1 
ATOM 2587 N NZ  . LYS C 1 133 ? 127.827 141.573 89.368  1.00 118.75 ? 223 LYS C NZ  1 
ATOM 2588 N N   . SER C 1 134 ? 123.783 136.977 93.638  1.00 111.41 ? 224 SER C N   1 
ATOM 2589 C CA  . SER C 1 134 ? 123.008 136.507 94.776  1.00 111.41 ? 224 SER C CA  1 
ATOM 2590 C C   . SER C 1 134 ? 123.764 135.449 95.553  1.00 111.41 ? 224 SER C C   1 
ATOM 2591 O O   . SER C 1 134 ? 123.865 135.530 96.788  1.00 111.41 ? 224 SER C O   1 
ATOM 2592 C CB  . SER C 1 134 ? 121.670 135.935 94.305  1.00 111.41 ? 224 SER C CB  1 
ATOM 2593 O OG  . SER C 1 134 ? 121.792 134.554 94.010  1.00 111.41 ? 224 SER C OG  1 
ATOM 2594 N N   . THR C 1 135 ? 124.289 134.456 94.844  1.00 110.71 ? 225 THR C N   1 
ATOM 2595 C CA  . THR C 1 135 ? 125.080 133.432 95.500  1.00 110.71 ? 225 THR C CA  1 
ATOM 2596 C C   . THR C 1 135 ? 126.204 134.060 96.305  1.00 110.71 ? 225 THR C C   1 
ATOM 2597 O O   . THR C 1 135 ? 126.426 133.712 97.468  1.00 110.71 ? 225 THR C O   1 
ATOM 2598 C CB  . THR C 1 135 ? 125.630 132.475 94.453  1.00 110.71 ? 225 THR C CB  1 
ATOM 2599 O OG1 . THR C 1 135 ? 124.616 132.227 93.472  1.00 110.71 ? 225 THR C OG1 1 
ATOM 2600 C CG2 . THR C 1 135 ? 126.026 131.172 95.097  1.00 110.71 ? 225 THR C CG2 1 
ATOM 2601 N N   . ASP C 1 136 ? 126.897 135.021 95.706  1.00 118.44 ? 226 ASP C N   1 
ATOM 2602 C CA  . ASP C 1 136 ? 128.057 135.622 96.344  1.00 118.44 ? 226 ASP C CA  1 
ATOM 2603 C C   . ASP C 1 136 ? 127.678 136.346 97.620  1.00 118.44 ? 226 ASP C C   1 
ATOM 2604 O O   . ASP C 1 136 ? 128.351 136.206 98.649  1.00 118.44 ? 226 ASP C O   1 
ATOM 2605 C CB  . ASP C 1 136 ? 128.731 136.589 95.382  1.00 118.44 ? 226 ASP C CB  1 
ATOM 2606 C CG  . ASP C 1 136 ? 129.967 137.216 95.973  1.00 118.44 ? 226 ASP C CG  1 
ATOM 2607 O OD1 . ASP C 1 136 ? 129.829 138.272 96.622  1.00 118.44 ? 226 ASP C OD1 1 
ATOM 2608 O OD2 . ASP C 1 136 ? 131.071 136.659 95.802  1.00 118.44 ? 226 ASP C OD2 1 
ATOM 2609 N N   . GLU C 1 137 ? 126.611 137.141 97.567  1.00 123.59 ? 227 GLU C N   1 
ATOM 2610 C CA  . GLU C 1 137 ? 126.237 137.937 98.728  1.00 123.59 ? 227 GLU C CA  1 
ATOM 2611 C C   . GLU C 1 137 ? 125.735 137.046 99.857  1.00 123.59 ? 227 GLU C C   1 
ATOM 2612 O O   . GLU C 1 137 ? 125.997 137.310 101.034 1.00 123.59 ? 227 GLU C O   1 
ATOM 2613 C CB  . GLU C 1 137 ? 125.191 138.981 98.342  1.00 123.59 ? 227 GLU C CB  1 
ATOM 2614 C CG  . GLU C 1 137 ? 125.774 140.264 97.756  1.00 123.59 ? 227 GLU C CG  1 
ATOM 2615 C CD  . GLU C 1 137 ? 126.403 141.169 98.804  1.00 123.59 ? 227 GLU C CD  1 
ATOM 2616 O OE1 . GLU C 1 137 ? 127.006 142.192 98.422  1.00 123.59 ? 227 GLU C OE1 1 
ATOM 2617 O OE2 . GLU C 1 137 ? 126.303 140.857 100.008 1.00 123.59 ? 227 GLU C OE2 1 
ATOM 2618 N N   . ARG C 1 138 ? 125.020 135.974 99.518  1.00 111.49 ? 228 ARG C N   1 
ATOM 2619 C CA  . ARG C 1 138 ? 124.646 135.013 100.550 1.00 111.49 ? 228 ARG C CA  1 
ATOM 2620 C C   . ARG C 1 138 ? 125.877 134.348 101.151 1.00 111.49 ? 228 ARG C C   1 
ATOM 2621 O O   . ARG C 1 138 ? 125.922 134.071 102.355 1.00 111.49 ? 228 ARG C O   1 
ATOM 2622 C CB  . ARG C 1 138 ? 123.696 133.969 99.972  1.00 111.49 ? 228 ARG C CB  1 
ATOM 2623 C CG  . ARG C 1 138 ? 122.264 134.442 99.854  1.00 111.49 ? 228 ARG C CG  1 
ATOM 2624 C CD  . ARG C 1 138 ? 121.561 133.812 98.668  1.00 111.49 ? 228 ARG C CD  1 
ATOM 2625 N NE  . ARG C 1 138 ? 120.127 133.714 98.903  1.00 111.49 ? 228 ARG C NE  1 
ATOM 2626 C CZ  . ARG C 1 138 ? 119.487 132.571 99.115  1.00 111.49 ? 228 ARG C CZ  1 
ATOM 2627 N NH1 . ARG C 1 138 ? 120.150 131.422 99.101  1.00 111.49 ? 228 ARG C NH1 1 
ATOM 2628 N NH2 . ARG C 1 138 ? 118.180 132.577 99.329  1.00 111.49 ? 228 ARG C NH2 1 
ATOM 2629 N N   . LEU C 1 139 ? 126.879 134.061 100.321 1.00 104.94 ? 229 LEU C N   1 
ATOM 2630 C CA  . LEU C 1 139 ? 128.113 133.507 100.854 1.00 104.94 ? 229 LEU C CA  1 
ATOM 2631 C C   . LEU C 1 139 ? 128.756 134.478 101.822 1.00 104.94 ? 229 LEU C C   1 
ATOM 2632 O O   . LEU C 1 139 ? 129.259 134.079 102.878 1.00 104.94 ? 229 LEU C O   1 
ATOM 2633 C CB  . LEU C 1 139 ? 129.063 133.162 99.717  1.00 104.94 ? 229 LEU C CB  1 
ATOM 2634 C CG  . LEU C 1 139 ? 128.514 132.035 98.856  1.00 104.94 ? 229 LEU C CG  1 
ATOM 2635 C CD1 . LEU C 1 139 ? 129.203 132.036 97.524  1.00 104.94 ? 229 LEU C CD1 1 
ATOM 2636 C CD2 . LEU C 1 139 ? 128.667 130.700 99.541  1.00 104.94 ? 229 LEU C CD2 1 
ATOM 2637 N N   . GLU C 1 140 ? 128.735 135.764 101.490 1.00 119.88 ? 230 GLU C N   1 
ATOM 2638 C CA  . GLU C 1 140 ? 129.232 136.756 102.434 1.00 119.88 ? 230 GLU C CA  1 
ATOM 2639 C C   . GLU C 1 140 ? 128.397 136.773 103.702 1.00 119.88 ? 230 GLU C C   1 
ATOM 2640 O O   . GLU C 1 140 ? 128.931 136.999 104.793 1.00 119.88 ? 230 GLU C O   1 
ATOM 2641 C CB  . GLU C 1 140 ? 129.240 138.151 101.810 1.00 119.88 ? 230 GLU C CB  1 
ATOM 2642 C CG  . GLU C 1 140 ? 129.987 139.173 102.659 1.00 119.88 ? 230 GLU C CG  1 
ATOM 2643 C CD  . GLU C 1 140 ? 130.148 140.513 101.975 1.00 119.88 ? 230 GLU C CD  1 
ATOM 2644 O OE1 . GLU C 1 140 ? 129.666 140.664 100.834 1.00 119.88 ? 230 GLU C OE1 1 
ATOM 2645 O OE2 . GLU C 1 140 ? 130.768 141.414 102.577 1.00 119.88 ? 230 GLU C OE2 1 
ATOM 2646 N N   . ASN C 1 141 ? 127.089 136.580 103.560 1.00 119.82 ? 231 ASN C N   1 
ATOM 2647 C CA  . ASN C 1 141 ? 126.220 136.444 104.718 1.00 119.82 ? 231 ASN C CA  1 
ATOM 2648 C C   . ASN C 1 141 ? 126.709 135.335 105.628 1.00 119.82 ? 231 ASN C C   1 
ATOM 2649 O O   . ASN C 1 141 ? 126.818 135.514 106.847 1.00 119.82 ? 231 ASN C O   1 
ATOM 2650 C CB  . ASN C 1 141 ? 124.792 136.160 104.261 1.00 119.82 ? 231 ASN C CB  1 
ATOM 2651 C CG  . ASN C 1 141 ? 123.899 137.370 104.365 1.00 119.82 ? 231 ASN C CG  1 
ATOM 2652 O OD1 . ASN C 1 141 ? 123.443 137.908 103.354 1.00 119.82 ? 231 ASN C OD1 1 
ATOM 2653 N ND2 . ASN C 1 141 ? 123.645 137.813 105.594 1.00 119.82 ? 231 ASN C ND2 1 
ATOM 2654 N N   . LEU C 1 142 ? 127.014 134.182 105.045 1.00 108.68 ? 232 LEU C N   1 
ATOM 2655 C CA  . LEU C 1 142 ? 127.580 133.092 105.825 1.00 108.68 ? 232 LEU C CA  1 
ATOM 2656 C C   . LEU C 1 142 ? 128.879 133.526 106.487 1.00 108.68 ? 232 LEU C C   1 
ATOM 2657 O O   . LEU C 1 142 ? 129.082 133.311 107.686 1.00 108.68 ? 232 LEU C O   1 
ATOM 2658 C CB  . LEU C 1 142 ? 127.794 131.877 104.933 1.00 108.68 ? 232 LEU C CB  1 
ATOM 2659 C CG  . LEU C 1 142 ? 126.469 131.205 104.596 1.00 108.68 ? 232 LEU C CG  1 
ATOM 2660 C CD1 . LEU C 1 142 ? 126.646 130.342 103.395 1.00 108.68 ? 232 LEU C CD1 1 
ATOM 2661 C CD2 . LEU C 1 142 ? 125.979 130.375 105.757 1.00 108.68 ? 232 LEU C CD2 1 
ATOM 2662 N N   . LEU C 1 143 ? 129.766 134.152 105.715 1.00 112.82 ? 233 LEU C N   1 
ATOM 2663 C CA  . LEU C 1 143 ? 131.056 134.565 106.250 1.00 112.82 ? 233 LEU C CA  1 
ATOM 2664 C C   . LEU C 1 143 ? 130.907 135.424 107.491 1.00 112.82 ? 233 LEU C C   1 
ATOM 2665 O O   . LEU C 1 143 ? 131.430 135.076 108.557 1.00 112.82 ? 233 LEU C O   1 
ATOM 2666 C CB  . LEU C 1 143 ? 131.851 135.323 105.194 1.00 112.82 ? 233 LEU C CB  1 
ATOM 2667 C CG  . LEU C 1 143 ? 132.550 134.474 104.132 1.00 112.82 ? 233 LEU C CG  1 
ATOM 2668 C CD1 . LEU C 1 143 ? 133.976 134.957 103.989 1.00 112.82 ? 233 LEU C CD1 1 
ATOM 2669 C CD2 . LEU C 1 143 ? 132.526 132.999 104.475 1.00 112.82 ? 233 LEU C CD2 1 
ATOM 2670 N N   . ASN C 1 144 ? 130.184 136.536 107.389 1.00 119.96 ? 234 ASN C N   1 
ATOM 2671 C CA  . ASN C 1 144 ? 130.153 137.429 108.538 1.00 119.96 ? 234 ASN C CA  1 
ATOM 2672 C C   . ASN C 1 144 ? 129.350 136.821 109.679 1.00 119.96 ? 234 ASN C C   1 
ATOM 2673 O O   . ASN C 1 144 ? 129.709 137.001 110.849 1.00 119.96 ? 234 ASN C O   1 
ATOM 2674 C CB  . ASN C 1 144 ? 129.621 138.822 108.179 1.00 119.96 ? 234 ASN C CB  1 
ATOM 2675 C CG  . ASN C 1 144 ? 128.334 138.785 107.399 1.00 119.96 ? 234 ASN C CG  1 
ATOM 2676 O OD1 . ASN C 1 144 ? 127.835 137.727 107.067 1.00 119.96 ? 234 ASN C OD1 1 
ATOM 2677 N ND2 . ASN C 1 144 ? 127.785 139.957 107.105 1.00 119.96 ? 234 ASN C ND2 1 
ATOM 2678 N N   . ILE C 1 145 ? 128.278 136.079 109.376 1.00 112.54 ? 235 ILE C N   1 
ATOM 2679 C CA  . ILE C 1 145 ? 127.496 135.532 110.474 1.00 112.54 ? 235 ILE C CA  1 
ATOM 2680 C C   . ILE C 1 145 ? 128.333 134.548 111.272 1.00 112.54 ? 235 ILE C C   1 
ATOM 2681 O O   . ILE C 1 145 ? 128.337 134.576 112.511 1.00 112.54 ? 235 ILE C O   1 
ATOM 2682 C CB  . ILE C 1 145 ? 126.181 134.910 109.966 1.00 112.54 ? 235 ILE C CB  1 
ATOM 2683 C CG1 . ILE C 1 145 ? 125.213 134.735 111.134 1.00 112.54 ? 235 ILE C CG1 1 
ATOM 2684 C CG2 . ILE C 1 145 ? 126.409 133.576 109.287 1.00 112.54 ? 235 ILE C CG2 1 
ATOM 2685 C CD1 . ILE C 1 145 ? 123.808 134.411 110.718 1.00 112.54 ? 235 ILE C CD1 1 
ATOM 2686 N N   . VAL C 1 146 ? 129.114 133.715 110.592 1.00 109.09 ? 236 VAL C N   1 
ATOM 2687 C CA  . VAL C 1 146 ? 129.924 132.765 111.331 1.00 109.09 ? 236 VAL C CA  1 
ATOM 2688 C C   . VAL C 1 146 ? 131.083 133.479 112.010 1.00 109.09 ? 236 VAL C C   1 
ATOM 2689 O O   . VAL C 1 146 ? 131.572 133.036 113.054 1.00 109.09 ? 236 VAL C O   1 
ATOM 2690 C CB  . VAL C 1 146 ? 130.387 131.625 110.413 1.00 109.09 ? 236 VAL C CB  1 
ATOM 2691 C CG1 . VAL C 1 146 ? 129.184 131.010 109.742 1.00 109.09 ? 236 VAL C CG1 1 
ATOM 2692 C CG2 . VAL C 1 146 ? 131.351 132.138 109.390 1.00 109.09 ? 236 VAL C CG2 1 
ATOM 2693 N N   . ARG C 1 147 ? 131.522 134.611 111.455 1.00 113.06 ? 237 ARG C N   1 
ATOM 2694 C CA  . ARG C 1 147 ? 132.494 135.411 112.192 1.00 113.06 ? 237 ARG C CA  1 
ATOM 2695 C C   . ARG C 1 147 ? 131.932 135.850 113.536 1.00 113.06 ? 237 ARG C C   1 
ATOM 2696 O O   . ARG C 1 147 ? 132.579 135.669 114.579 1.00 113.06 ? 237 ARG C O   1 
ATOM 2697 C CB  . ARG C 1 147 ? 132.921 136.630 111.383 1.00 113.06 ? 237 ARG C CB  1 
ATOM 2698 C CG  . ARG C 1 147 ? 134.135 136.419 110.523 1.00 113.06 ? 237 ARG C CG  1 
ATOM 2699 C CD  . ARG C 1 147 ? 134.474 137.704 109.820 1.00 113.06 ? 237 ARG C CD  1 
ATOM 2700 N NE  . ARG C 1 147 ? 135.491 137.501 108.804 1.00 113.06 ? 237 ARG C NE  1 
ATOM 2701 C CZ  . ARG C 1 147 ? 135.321 137.792 107.523 1.00 113.06 ? 237 ARG C CZ  1 
ATOM 2702 N NH1 . ARG C 1 147 ? 134.171 138.302 107.105 1.00 113.06 ? 237 ARG C NH1 1 
ATOM 2703 N NH2 . ARG C 1 147 ? 136.301 137.572 106.659 1.00 113.06 ? 237 ARG C NH2 1 
ATOM 2704 N N   . GLU C 1 148 ? 130.738 136.444 113.527 1.00 109.59 ? 238 GLU C N   1 
ATOM 2705 C CA  . GLU C 1 148 ? 130.140 136.854 114.789 1.00 109.59 ? 238 GLU C CA  1 
ATOM 2706 C C   . GLU C 1 148 ? 129.976 135.671 115.718 1.00 109.59 ? 238 GLU C C   1 
ATOM 2707 O O   . GLU C 1 148 ? 130.165 135.804 116.930 1.00 109.59 ? 238 GLU C O   1 
ATOM 2708 C CB  . GLU C 1 148 ? 128.788 137.538 114.592 1.00 109.59 ? 238 GLU C CB  1 
ATOM 2709 C CG  . GLU C 1 148 ? 128.857 138.920 113.982 1.00 109.59 ? 238 GLU C CG  1 
ATOM 2710 C CD  . GLU C 1 148 ? 128.419 138.952 112.540 1.00 109.59 ? 238 GLU C CD  1 
ATOM 2711 O OE1 . GLU C 1 148 ? 127.722 138.009 112.126 1.00 109.59 ? 238 GLU C OE1 1 
ATOM 2712 O OE2 . GLU C 1 148 ? 128.766 139.912 111.820 1.00 109.59 ? 238 GLU C OE2 1 
ATOM 2713 N N   . ILE C 1 149 ? 129.613 134.512 115.176 1.00 100.53 ? 239 ILE C N   1 
ATOM 2714 C CA  . ILE C 1 149 ? 129.450 133.344 116.030 1.00 100.53 ? 239 ILE C CA  1 
ATOM 2715 C C   . ILE C 1 149 ? 130.773 132.981 116.684 1.00 100.53 ? 239 ILE C C   1 
ATOM 2716 O O   . ILE C 1 149 ? 130.833 132.682 117.881 1.00 100.53 ? 239 ILE C O   1 
ATOM 2717 C CB  . ILE C 1 149 ? 128.873 132.169 115.230 1.00 100.53 ? 239 ILE C CB  1 
ATOM 2718 C CG1 . ILE C 1 149 ? 127.411 132.438 114.916 1.00 100.53 ? 239 ILE C CG1 1 
ATOM 2719 C CG2 . ILE C 1 149 ? 128.974 130.903 116.033 1.00 100.53 ? 239 ILE C CG2 1 
ATOM 2720 C CD1 . ILE C 1 149 ? 126.698 131.248 114.378 1.00 100.53 ? 239 ILE C CD1 1 
ATOM 2721 N N   . LEU C 1 150 ? 131.856 132.999 115.908 1.00 96.85  ? 240 LEU C N   1 
ATOM 2722 C CA  . LEU C 1 150 ? 133.156 132.687 116.481 1.00 96.85  ? 240 LEU C CA  1 
ATOM 2723 C C   . LEU C 1 150 ? 133.508 133.662 117.587 1.00 96.85  ? 240 LEU C C   1 
ATOM 2724 O O   . LEU C 1 150 ? 134.009 133.254 118.641 1.00 96.85  ? 240 LEU C O   1 
ATOM 2725 C CB  . LEU C 1 150 ? 134.236 132.699 115.401 1.00 96.85  ? 240 LEU C CB  1 
ATOM 2726 C CG  . LEU C 1 150 ? 135.642 132.271 115.837 1.00 96.85  ? 240 LEU C CG  1 
ATOM 2727 C CD1 . LEU C 1 150 ? 136.329 131.474 114.745 1.00 96.85  ? 240 LEU C CD1 1 
ATOM 2728 C CD2 . LEU C 1 150 ? 136.491 133.478 116.191 1.00 96.85  ? 240 LEU C CD2 1 
ATOM 2729 N N   . ASP C 1 151 ? 133.241 134.947 117.373 1.00 105.93 ? 241 ASP C N   1 
ATOM 2730 C CA  . ASP C 1 151 ? 133.556 135.929 118.405 1.00 105.93 ? 241 ASP C CA  1 
ATOM 2731 C C   . ASP C 1 151 ? 132.713 135.697 119.655 1.00 105.93 ? 241 ASP C C   1 
ATOM 2732 O O   . ASP C 1 151 ? 133.215 135.778 120.786 1.00 105.93 ? 241 ASP C O   1 
ATOM 2733 C CB  . ASP C 1 151 ? 133.347 137.341 117.866 1.00 105.93 ? 241 ASP C CB  1 
ATOM 2734 C CG  . ASP C 1 151 ? 133.942 138.398 118.770 1.00 105.93 ? 241 ASP C CG  1 
ATOM 2735 O OD1 . ASP C 1 151 ? 134.996 138.128 119.380 1.00 105.93 ? 241 ASP C OD1 1 
ATOM 2736 O OD2 . ASP C 1 151 ? 133.358 139.497 118.869 1.00 105.93 ? 241 ASP C OD2 1 
ATOM 2737 N N   . VAL C 1 152 ? 131.426 135.411 119.464 1.00 94.27  ? 242 VAL C N   1 
ATOM 2738 C CA  . VAL C 1 152 ? 130.535 135.180 120.594 1.00 94.27  ? 242 VAL C CA  1 
ATOM 2739 C C   . VAL C 1 152 ? 130.998 133.972 121.388 1.00 94.27  ? 242 VAL C C   1 
ATOM 2740 O O   . VAL C 1 152 ? 130.956 133.968 122.622 1.00 94.27  ? 242 VAL C O   1 
ATOM 2741 C CB  . VAL C 1 152 ? 129.086 135.023 120.103 1.00 94.27  ? 242 VAL C CB  1 
ATOM 2742 C CG1 . VAL C 1 152 ? 128.250 134.326 121.143 1.00 94.27  ? 242 VAL C CG1 1 
ATOM 2743 C CG2 . VAL C 1 152 ? 128.498 136.381 119.794 1.00 94.27  ? 242 VAL C CG2 1 
ATOM 2744 N N   . GLN C 1 153 ? 131.470 132.937 120.699 1.00 91.00  ? 243 GLN C N   1 
ATOM 2745 C CA  . GLN C 1 153 ? 131.946 131.758 121.408 1.00 91.00  ? 243 GLN C CA  1 
ATOM 2746 C C   . GLN C 1 153 ? 133.244 132.047 122.144 1.00 91.00  ? 243 GLN C C   1 
ATOM 2747 O O   . GLN C 1 153 ? 133.450 131.568 123.263 1.00 91.00  ? 243 GLN C O   1 
ATOM 2748 C CB  . GLN C 1 153 ? 132.119 130.599 120.436 1.00 91.00  ? 243 GLN C CB  1 
ATOM 2749 C CG  . GLN C 1 153 ? 130.800 130.050 119.945 1.00 91.00  ? 243 GLN C CG  1 
ATOM 2750 C CD  . GLN C 1 153 ? 129.713 130.161 120.990 1.00 91.00  ? 243 GLN C CD  1 
ATOM 2751 O OE1 . GLN C 1 153 ? 128.944 131.122 121.013 1.00 91.00  ? 243 GLN C OE1 1 
ATOM 2752 N NE2 . GLN C 1 153 ? 129.658 129.185 121.879 1.00 91.00  ? 243 GLN C NE2 1 
ATOM 2753 N N   . ARG C 1 154 ? 134.133 132.821 121.527 1.00 96.03  ? 244 ARG C N   1 
ATOM 2754 C CA  . ARG C 1 154 ? 135.308 133.295 122.244 1.00 96.03  ? 244 ARG C CA  1 
ATOM 2755 C C   . ARG C 1 154 ? 134.916 133.947 123.561 1.00 96.03  ? 244 ARG C C   1 
ATOM 2756 O O   . ARG C 1 154 ? 135.407 133.565 124.636 1.00 96.03  ? 244 ARG C O   1 
ATOM 2757 C CB  . ARG C 1 154 ? 136.076 134.282 121.370 1.00 96.03  ? 244 ARG C CB  1 
ATOM 2758 C CG  . ARG C 1 154 ? 137.045 135.157 122.135 1.00 96.03  ? 244 ARG C CG  1 
ATOM 2759 C CD  . ARG C 1 154 ? 137.754 136.135 121.214 1.00 96.03  ? 244 ARG C CD  1 
ATOM 2760 N NE  . ARG C 1 154 ? 138.477 135.463 120.138 1.00 96.03  ? 244 ARG C NE  1 
ATOM 2761 C CZ  . ARG C 1 154 ? 138.091 135.451 118.867 1.00 96.03  ? 244 ARG C CZ  1 
ATOM 2762 N NH1 . ARG C 1 154 ? 136.978 136.076 118.503 1.00 96.03  ? 244 ARG C NH1 1 
ATOM 2763 N NH2 . ARG C 1 154 ? 138.818 134.815 117.959 1.00 96.03  ? 244 ARG C NH2 1 
ATOM 2764 N N   . ASP C 1 155 ? 134.014 134.919 123.499 1.00 92.61  ? 245 ASP C N   1 
ATOM 2765 C CA  . ASP C 1 155 ? 133.646 135.653 124.699 1.00 92.61  ? 245 ASP C CA  1 
ATOM 2766 C C   . ASP C 1 155 ? 132.902 134.794 125.713 1.00 92.61  ? 245 ASP C C   1 
ATOM 2767 O O   . ASP C 1 155 ? 133.095 134.973 126.921 1.00 92.61  ? 245 ASP C O   1 
ATOM 2768 C CB  . ASP C 1 155 ? 132.802 136.873 124.335 1.00 92.61  ? 245 ASP C CB  1 
ATOM 2769 C CG  . ASP C 1 155 ? 132.830 137.927 125.412 1.00 92.61  ? 245 ASP C CG  1 
ATOM 2770 O OD1 . ASP C 1 155 ? 133.832 138.666 125.493 1.00 92.61  ? 245 ASP C OD1 1 
ATOM 2771 O OD2 . ASP C 1 155 ? 131.862 138.006 126.192 1.00 92.61  ? 245 ASP C OD2 1 
ATOM 2772 N N   . MET C 1 156 ? 132.071 133.857 125.262 1.00 82.05  ? 246 MET C N   1 
ATOM 2773 C CA  . MET C 1 156 ? 131.472 132.920 126.198 1.00 82.05  ? 246 MET C CA  1 
ATOM 2774 C C   . MET C 1 156 ? 132.535 132.093 126.893 1.00 82.05  ? 246 MET C C   1 
ATOM 2775 O O   . MET C 1 156 ? 132.437 131.836 128.094 1.00 82.05  ? 246 MET C O   1 
ATOM 2776 C CB  . MET C 1 156 ? 130.482 131.999 125.494 1.00 82.05  ? 246 MET C CB  1 
ATOM 2777 C CG  . MET C 1 156 ? 129.104 132.577 125.327 1.00 82.05  ? 246 MET C CG  1 
ATOM 2778 S SD  . MET C 1 156 ? 127.945 131.302 124.815 1.00 82.05  ? 246 MET C SD  1 
ATOM 2779 C CE  . MET C 1 156 ? 127.889 130.301 126.294 1.00 82.05  ? 246 MET C CE  1 
ATOM 2780 N N   . ARG C 1 157 ? 133.535 131.630 126.149 1.00 78.99  ? 247 ARG C N   1 
ATOM 2781 C CA  . ARG C 1 157 ? 134.599 130.877 126.790 1.00 78.99  ? 247 ARG C CA  1 
ATOM 2782 C C   . ARG C 1 157 ? 135.265 131.710 127.869 1.00 78.99  ? 247 ARG C C   1 
ATOM 2783 O O   . ARG C 1 157 ? 135.555 131.208 128.964 1.00 78.99  ? 247 ARG C O   1 
ATOM 2784 C CB  . ARG C 1 157 ? 135.626 130.424 125.767 1.00 78.99  ? 247 ARG C CB  1 
ATOM 2785 C CG  . ARG C 1 157 ? 137.000 130.310 126.369 1.00 78.99  ? 247 ARG C CG  1 
ATOM 2786 C CD  . ARG C 1 157 ? 137.940 129.583 125.466 1.00 78.99  ? 247 ARG C CD  1 
ATOM 2787 N NE  . ARG C 1 157 ? 137.888 128.149 125.698 1.00 78.99  ? 247 ARG C NE  1 
ATOM 2788 C CZ  . ARG C 1 157 ? 138.838 127.305 125.318 1.00 78.99  ? 247 ARG C CZ  1 
ATOM 2789 N NH1 . ARG C 1 157 ? 139.915 127.752 124.690 1.00 78.99  ? 247 ARG C NH1 1 
ATOM 2790 N NH2 . ARG C 1 157 ? 138.711 126.015 125.566 1.00 78.99  ? 247 ARG C NH2 1 
ATOM 2791 N N   . ASN C 1 158 ? 135.513 132.984 127.580 1.00 80.19  ? 248 ASN C N   1 
ATOM 2792 C CA  . ASN C 1 158 ? 136.095 133.855 128.597 1.00 80.19  ? 248 ASN C CA  1 
ATOM 2793 C C   . ASN C 1 158 ? 135.178 133.962 129.810 1.00 80.19  ? 248 ASN C C   1 
ATOM 2794 O O   . ASN C 1 158 ? 135.628 133.896 130.962 1.00 80.19  ? 248 ASN C O   1 
ATOM 2795 C CB  . ASN C 1 158 ? 136.384 135.232 128.008 1.00 80.19  ? 248 ASN C CB  1 
ATOM 2796 C CG  . ASN C 1 158 ? 137.602 135.231 127.118 1.00 80.19  ? 248 ASN C CG  1 
ATOM 2797 O OD1 . ASN C 1 158 ? 138.552 134.487 127.355 1.00 80.19  ? 248 ASN C OD1 1 
ATOM 2798 N ND2 . ASN C 1 158 ? 137.583 136.062 126.084 1.00 80.19  ? 248 ASN C ND2 1 
ATOM 2799 N N   . ASP C 1 159 ? 133.880 134.111 129.564 1.00 70.53  ? 249 ASP C N   1 
ATOM 2800 C CA  . ASP C 1 159 ? 132.923 134.199 130.656 1.00 70.53  ? 249 ASP C CA  1 
ATOM 2801 C C   . ASP C 1 159 ? 132.943 132.941 131.513 1.00 70.53  ? 249 ASP C C   1 
ATOM 2802 O O   . ASP C 1 159 ? 132.899 133.018 132.746 1.00 70.53  ? 249 ASP C O   1 
ATOM 2803 C CB  . ASP C 1 159 ? 131.532 134.441 130.080 1.00 70.53  ? 249 ASP C CB  1 
ATOM 2804 C CG  . ASP C 1 159 ? 130.579 135.032 131.086 1.00 70.53  ? 249 ASP C CG  1 
ATOM 2805 O OD1 . ASP C 1 159 ? 130.771 136.207 131.453 1.00 70.53  ? 249 ASP C OD1 1 
ATOM 2806 O OD2 . ASP C 1 159 ? 129.625 134.341 131.493 1.00 70.53  ? 249 ASP C OD2 1 
ATOM 2807 N N   . LEU C 1 160 ? 133.036 131.778 130.878 1.00 60.37  ? 250 LEU C N   1 
ATOM 2808 C CA  . LEU C 1 160 ? 133.017 130.528 131.622 1.00 60.37  ? 250 LEU C CA  1 
ATOM 2809 C C   . LEU C 1 160 ? 134.283 130.365 132.443 1.00 60.37  ? 250 LEU C C   1 
ATOM 2810 O O   . LEU C 1 160 ? 134.234 129.894 133.583 1.00 60.37  ? 250 LEU C O   1 
ATOM 2811 C CB  . LEU C 1 160 ? 132.845 129.356 130.668 1.00 60.37  ? 250 LEU C CB  1 
ATOM 2812 C CG  . LEU C 1 160 ? 132.128 128.190 131.319 1.00 60.37  ? 250 LEU C CG  1 
ATOM 2813 C CD1 . LEU C 1 160 ? 130.790 128.671 131.796 1.00 60.37  ? 250 LEU C CD1 1 
ATOM 2814 C CD2 . LEU C 1 160 ? 131.954 127.085 130.327 1.00 60.37  ? 250 LEU C CD2 1 
ATOM 2815 N N   . SER C 1 161 ? 135.431 130.727 131.873 1.00 69.88  ? 251 SER C N   1 
ATOM 2816 C CA  . SER C 1 161 ? 136.645 130.783 132.677 1.00 69.88  ? 251 SER C CA  1 
ATOM 2817 C C   . SER C 1 161 ? 136.447 131.657 133.902 1.00 69.88  ? 251 SER C C   1 
ATOM 2818 O O   . SER C 1 161 ? 136.843 131.275 135.017 1.00 69.88  ? 251 SER C O   1 
ATOM 2819 C CB  . SER C 1 161 ? 137.806 131.313 131.844 1.00 69.88  ? 251 SER C CB  1 
ATOM 2820 O OG  . SER C 1 161 ? 138.963 131.489 132.639 1.00 69.88  ? 251 SER C OG  1 
ATOM 2821 N N   . ASN C 1 162 ? 135.843 132.827 133.710 1.00 62.55  ? 252 ASN C N   1 
ATOM 2822 C CA  . ASN C 1 162 ? 135.556 133.699 134.838 1.00 62.55  ? 252 ASN C CA  1 
ATOM 2823 C C   . ASN C 1 162 ? 134.748 132.956 135.893 1.00 62.55  ? 252 ASN C C   1 
ATOM 2824 O O   . ASN C 1 162 ? 135.082 132.973 137.087 1.00 62.55  ? 252 ASN C O   1 
ATOM 2825 C CB  . ASN C 1 162 ? 134.806 134.936 134.350 1.00 62.55  ? 252 ASN C CB  1 
ATOM 2826 C CG  . ASN C 1 162 ? 135.176 136.181 135.121 1.00 62.55  ? 252 ASN C CG  1 
ATOM 2827 O OD1 . ASN C 1 162 ? 136.151 136.192 135.867 1.00 62.55  ? 252 ASN C OD1 1 
ATOM 2828 N ND2 . ASN C 1 162 ? 134.389 137.237 134.954 1.00 62.55  ? 252 ASN C ND2 1 
ATOM 2829 N N   . LEU C 1 163 ? 133.694 132.271 135.461 1.00 54.02  ? 253 LEU C N   1 
ATOM 2830 C CA  . LEU C 1 163 ? 132.816 131.626 136.426 1.00 54.02  ? 253 LEU C CA  1 
ATOM 2831 C C   . LEU C 1 163 ? 133.550 130.513 137.162 1.00 54.02  ? 253 LEU C C   1 
ATOM 2832 O O   . LEU C 1 163 ? 133.320 130.288 138.356 1.00 54.02  ? 253 LEU C O   1 
ATOM 2833 C CB  . LEU C 1 163 ? 131.573 131.079 135.733 1.00 54.02  ? 253 LEU C CB  1 
ATOM 2834 C CG  . LEU C 1 163 ? 130.425 130.765 136.688 1.00 54.02  ? 253 LEU C CG  1 
ATOM 2835 C CD1 . LEU C 1 163 ? 129.836 132.060 137.197 1.00 54.02  ? 253 LEU C CD1 1 
ATOM 2836 C CD2 . LEU C 1 163 ? 129.365 129.945 136.032 1.00 54.02  ? 253 LEU C CD2 1 
ATOM 2837 N N   . THR C 1 164 ? 134.442 129.807 136.467 1.00 48.72  ? 254 THR C N   1 
ATOM 2838 C CA  . THR C 1 164 ? 135.195 128.738 137.115 1.00 48.72  ? 254 THR C CA  1 
ATOM 2839 C C   . THR C 1 164 ? 136.079 129.295 138.211 1.00 48.72  ? 254 THR C C   1 
ATOM 2840 O O   . THR C 1 164 ? 136.083 128.793 139.346 1.00 48.72  ? 254 THR C O   1 
ATOM 2841 C CB  . THR C 1 164 ? 136.046 127.990 136.100 1.00 48.72  ? 254 THR C CB  1 
ATOM 2842 O OG1 . THR C 1 164 ? 135.218 127.552 135.026 1.00 48.72  ? 254 THR C OG1 1 
ATOM 2843 C CG2 . THR C 1 164 ? 136.674 126.787 136.745 1.00 48.72  ? 254 THR C CG2 1 
ATOM 2844 N N   . ARG C 1 165 ? 136.863 130.321 137.881 1.00 57.92  ? 255 ARG C N   1 
ATOM 2845 C CA  . ARG C 1 165 ? 137.639 130.966 138.925 1.00 57.92  ? 255 ARG C CA  1 
ATOM 2846 C C   . ARG C 1 165 ? 136.769 131.353 140.100 1.00 57.92  ? 255 ARG C C   1 
ATOM 2847 O O   . ARG C 1 165 ? 137.146 131.088 141.247 1.00 57.92  ? 255 ARG C O   1 
ATOM 2848 C CB  . ARG C 1 165 ? 138.355 132.203 138.404 1.00 57.92  ? 255 ARG C CB  1 
ATOM 2849 C CG  . ARG C 1 165 ? 139.575 131.914 137.571 1.00 57.92  ? 255 ARG C CG  1 
ATOM 2850 C CD  . ARG C 1 165 ? 140.337 133.195 137.275 1.00 57.92  ? 255 ARG C CD  1 
ATOM 2851 N NE  . ARG C 1 165 ? 139.498 134.180 136.596 1.00 57.92  ? 255 ARG C NE  1 
ATOM 2852 C CZ  . ARG C 1 165 ? 139.286 134.206 135.285 1.00 57.92  ? 255 ARG C CZ  1 
ATOM 2853 N NH1 . ARG C 1 165 ? 139.851 133.299 134.499 1.00 57.92  ? 255 ARG C NH1 1 
ATOM 2854 N NH2 . ARG C 1 165 ? 138.506 135.138 134.760 1.00 57.92  ? 255 ARG C NH2 1 
ATOM 2855 N N   . LYS C 1 166 ? 135.601 131.942 139.843 1.00 49.59  ? 256 LYS C N   1 
ATOM 2856 C CA  . LYS C 1 166 ? 134.802 132.427 140.962 1.00 49.59  ? 256 LYS C CA  1 
ATOM 2857 C C   . LYS C 1 166 ? 134.285 131.290 141.835 1.00 49.59  ? 256 LYS C C   1 
ATOM 2858 O O   . LYS C 1 166 ? 134.299 131.394 143.071 1.00 49.59  ? 256 LYS C O   1 
ATOM 2859 C CB  . LYS C 1 166 ? 133.650 133.279 140.461 1.00 49.59  ? 256 LYS C CB  1 
ATOM 2860 C CG  . LYS C 1 166 ? 133.810 134.710 140.852 1.00 49.59  ? 256 LYS C CG  1 
ATOM 2861 C CD  . LYS C 1 166 ? 132.698 135.536 140.296 1.00 49.59  ? 256 LYS C CD  1 
ATOM 2862 C CE  . LYS C 1 166 ? 133.033 137.003 140.394 1.00 49.59  ? 256 LYS C CE  1 
ATOM 2863 N NZ  . LYS C 1 166 ? 132.015 137.839 139.706 1.00 49.59  ? 256 LYS C NZ  1 
ATOM 2864 N N   . VAL C 1 167 ? 133.835 130.197 141.226 1.00 40.60  ? 257 VAL C N   1 
ATOM 2865 C CA  . VAL C 1 167 ? 133.331 129.097 142.036 1.00 40.60  ? 257 VAL C CA  1 
ATOM 2866 C C   . VAL C 1 167 ? 134.447 128.515 142.887 1.00 40.60  ? 257 VAL C C   1 
ATOM 2867 O O   . VAL C 1 167 ? 134.264 128.249 144.082 1.00 40.60  ? 257 VAL C O   1 
ATOM 2868 C CB  . VAL C 1 167 ? 132.671 128.028 141.156 1.00 40.60  ? 257 VAL C CB  1 
ATOM 2869 C CG1 . VAL C 1 167 ? 132.596 126.730 141.900 1.00 40.60  ? 257 VAL C CG1 1 
ATOM 2870 C CG2 . VAL C 1 167 ? 131.292 128.473 140.779 1.00 40.60  ? 257 VAL C CG2 1 
ATOM 2871 N N   . ASP C 1 168 ? 135.629 128.331 142.305 1.00 43.28  ? 258 ASP C N   1 
ATOM 2872 C CA  . ASP C 1 168 ? 136.715 127.785 143.107 1.00 43.28  ? 258 ASP C CA  1 
ATOM 2873 C C   . ASP C 1 168 ? 137.065 128.705 144.263 1.00 43.28  ? 258 ASP C C   1 
ATOM 2874 O O   . ASP C 1 168 ? 137.273 128.248 145.397 1.00 43.28  ? 258 ASP C O   1 
ATOM 2875 C CB  . ASP C 1 168 ? 137.934 127.534 142.240 1.00 43.28  ? 258 ASP C CB  1 
ATOM 2876 C CG  . ASP C 1 168 ? 138.073 126.091 141.874 1.00 43.28  ? 258 ASP C CG  1 
ATOM 2877 O OD1 . ASP C 1 168 ? 137.223 125.307 142.333 1.00 43.28  ? 258 ASP C OD1 1 
ATOM 2878 O OD2 . ASP C 1 168 ? 139.019 125.736 141.145 1.00 43.28  ? 258 ASP C OD2 1 
ATOM 2879 N N   . ARG C 1 169 ? 137.167 130.001 143.984 1.00 46.67  ? 259 ARG C N   1 
ATOM 2880 C CA  . ARG C 1 169 ? 137.378 130.972 145.048 1.00 46.67  ? 259 ARG C CA  1 
ATOM 2881 C C   . ARG C 1 169 ? 136.414 130.739 146.198 1.00 46.67  ? 259 ARG C C   1 
ATOM 2882 O O   . ARG C 1 169 ? 136.835 130.528 147.344 1.00 46.67  ? 259 ARG C O   1 
ATOM 2883 C CB  . ARG C 1 169 ? 137.202 132.377 144.492 1.00 46.67  ? 259 ARG C CB  1 
ATOM 2884 C CG  . ARG C 1 169 ? 137.074 133.433 145.539 1.00 46.67  ? 259 ARG C CG  1 
ATOM 2885 C CD  . ARG C 1 169 ? 138.429 133.793 145.991 1.00 46.67  ? 259 ARG C CD  1 
ATOM 2886 N NE  . ARG C 1 169 ? 139.145 134.441 144.910 1.00 46.67  ? 259 ARG C NE  1 
ATOM 2887 C CZ  . ARG C 1 169 ? 140.460 134.575 144.881 1.00 46.67  ? 259 ARG C CZ  1 
ATOM 2888 N NH1 . ARG C 1 169 ? 141.192 134.090 145.870 1.00 46.67  ? 259 ARG C NH1 1 
ATOM 2889 N NH2 . ARG C 1 169 ? 141.044 135.185 143.863 1.00 46.67  ? 259 ARG C NH2 1 
ATOM 2890 N N   . MET C 1 170 ? 135.118 130.757 145.907 1.00 39.67  ? 260 MET C N   1 
ATOM 2891 C CA  . MET C 1 170 ? 134.140 130.622 146.977 1.00 39.67  ? 260 MET C CA  1 
ATOM 2892 C C   . MET C 1 170 ? 134.329 129.310 147.723 1.00 39.67  ? 260 MET C C   1 
ATOM 2893 O O   . MET C 1 170 ? 134.121 129.236 148.941 1.00 39.67  ? 260 MET C O   1 
ATOM 2894 C CB  . MET C 1 170 ? 132.728 130.727 146.411 1.00 39.67  ? 260 MET C CB  1 
ATOM 2895 C CG  . MET C 1 170 ? 131.656 130.712 147.459 1.00 39.67  ? 260 MET C CG  1 
ATOM 2896 S SD  . MET C 1 170 ? 130.051 130.761 146.692 1.00 39.67  ? 260 MET C SD  1 
ATOM 2897 C CE  . MET C 1 170 ? 130.175 129.270 145.734 1.00 39.67  ? 260 MET C CE  1 
ATOM 2898 N N   . ASP C 1 171 ? 134.722 128.259 147.006 1.00 41.96  ? 261 ASP C N   1 
ATOM 2899 C CA  . ASP C 1 171 ? 134.959 126.984 147.668 1.00 41.96  ? 261 ASP C CA  1 
ATOM 2900 C C   . ASP C 1 171 ? 136.017 127.128 148.743 1.00 41.96  ? 261 ASP C C   1 
ATOM 2901 O O   . ASP C 1 171 ? 135.816 126.711 149.895 1.00 41.96  ? 261 ASP C O   1 
ATOM 2902 C CB  . ASP C 1 171 ? 135.387 125.938 146.646 1.00 41.96  ? 261 ASP C CB  1 
ATOM 2903 C CG  . ASP C 1 171 ? 135.449 124.550 147.229 1.00 41.96  ? 261 ASP C CG  1 
ATOM 2904 O OD1 . ASP C 1 171 ? 135.096 124.390 148.409 1.00 41.96  ? 261 ASP C OD1 1 
ATOM 2905 O OD2 . ASP C 1 171 ? 135.842 123.613 146.507 1.00 41.96  ? 261 ASP C OD2 1 
ATOM 2906 N N   . MET C 1 172 ? 137.157 127.698 148.372 1.00 38.38  ? 262 MET C N   1 
ATOM 2907 C CA  . MET C 1 172 ? 138.199 127.935 149.361 1.00 38.38  ? 262 MET C CA  1 
ATOM 2908 C C   . MET C 1 172 ? 137.641 128.716 150.535 1.00 38.38  ? 262 MET C C   1 
ATOM 2909 O O   . MET C 1 172 ? 137.890 128.377 151.702 1.00 38.38  ? 262 MET C O   1 
ATOM 2910 C CB  . MET C 1 172 ? 139.370 128.682 148.733 1.00 38.38  ? 262 MET C CB  1 
ATOM 2911 C CG  . MET C 1 172 ? 140.533 128.873 149.666 1.00 38.38  ? 262 MET C CG  1 
ATOM 2912 S SD  . MET C 1 172 ? 140.427 130.373 150.652 1.00 38.38  ? 262 MET C SD  1 
ATOM 2913 C CE  . MET C 1 172 ? 141.059 131.570 149.497 1.00 38.38  ? 262 MET C CE  1 
ATOM 2914 N N   . ARG C 1 173 ? 136.864 129.761 150.243 1.00 40.98  ? 263 ARG C N   1 
ATOM 2915 C CA  . ARG C 1 173 ? 136.383 130.637 151.309 1.00 40.98  ? 263 ARG C CA  1 
ATOM 2916 C C   . ARG C 1 173 ? 135.555 129.866 152.323 1.00 40.98  ? 263 ARG C C   1 
ATOM 2917 O O   . ARG C 1 173 ? 135.773 129.972 153.537 1.00 40.98  ? 263 ARG C O   1 
ATOM 2918 C CB  . ARG C 1 173 ? 135.561 131.792 150.741 1.00 40.98  ? 263 ARG C CB  1 
ATOM 2919 C CG  . ARG C 1 173 ? 135.113 132.757 151.821 1.00 40.98  ? 263 ARG C CG  1 
ATOM 2920 C CD  . ARG C 1 173 ? 134.194 133.829 151.302 1.00 40.98  ? 263 ARG C CD  1 
ATOM 2921 N NE  . ARG C 1 173 ? 134.664 134.386 150.043 1.00 40.98  ? 263 ARG C NE  1 
ATOM 2922 C CZ  . ARG C 1 173 ? 135.561 135.355 149.954 1.00 40.98  ? 263 ARG C CZ  1 
ATOM 2923 N NH1 . ARG C 1 173 ? 136.092 135.866 151.052 1.00 40.98  ? 263 ARG C NH1 1 
ATOM 2924 N NH2 . ARG C 1 173 ? 135.930 135.809 148.769 1.00 40.98  ? 263 ARG C NH2 1 
ATOM 2925 N N   . LEU C 1 174 ? 134.595 129.085 151.841 1.00 41.50  ? 264 LEU C N   1 
ATOM 2926 C CA  . LEU C 1 174 ? 133.716 128.411 152.785 1.00 41.50  ? 264 LEU C CA  1 
ATOM 2927 C C   . LEU C 1 174 ? 134.442 127.320 153.546 1.00 41.50  ? 264 LEU C C   1 
ATOM 2928 O O   . LEU C 1 174 ? 134.226 127.164 154.753 1.00 41.50  ? 264 LEU C O   1 
ATOM 2929 C CB  . LEU C 1 174 ? 132.489 127.849 152.084 1.00 41.50  ? 264 LEU C CB  1 
ATOM 2930 C CG  . LEU C 1 174 ? 131.390 128.873 152.337 1.00 41.50  ? 264 LEU C CG  1 
ATOM 2931 C CD1 . LEU C 1 174 ? 130.464 129.038 151.151 1.00 41.50  ? 264 LEU C CD1 1 
ATOM 2932 C CD2 . LEU C 1 174 ? 130.636 128.520 153.595 1.00 41.50  ? 264 LEU C CD2 1 
ATOM 2933 N N   . SER C 1 175 ? 135.299 126.554 152.873 1.00 43.65  ? 265 SER C N   1 
ATOM 2934 C CA  . SER C 1 175 ? 136.083 125.579 153.618 1.00 43.65  ? 265 SER C CA  1 
ATOM 2935 C C   . SER C 1 175 ? 136.820 126.242 154.769 1.00 43.65  ? 265 SER C C   1 
ATOM 2936 O O   . SER C 1 175 ? 136.758 125.775 155.919 1.00 43.65  ? 265 SER C O   1 
ATOM 2937 C CB  . SER C 1 175 ? 137.065 124.882 152.693 1.00 43.65  ? 265 SER C CB  1 
ATOM 2938 O OG  . SER C 1 175 ? 137.920 124.046 153.441 1.00 43.65  ? 265 SER C OG  1 
ATOM 2939 N N   . ARG C 1 176 ? 137.506 127.348 154.488 1.00 48.82  ? 266 ARG C N   1 
ATOM 2940 C CA  . ARG C 1 176 ? 138.224 128.023 155.556 1.00 48.82  ? 266 ARG C CA  1 
ATOM 2941 C C   . ARG C 1 176 ? 137.282 128.418 156.675 1.00 48.82  ? 266 ARG C C   1 
ATOM 2942 O O   . ARG C 1 176 ? 137.462 128.010 157.827 1.00 48.82  ? 266 ARG C O   1 
ATOM 2943 C CB  . ARG C 1 176 ? 138.934 129.263 155.035 1.00 48.82  ? 266 ARG C CB  1 
ATOM 2944 C CG  . ARG C 1 176 ? 139.490 130.109 156.161 1.00 48.82  ? 266 ARG C CG  1 
ATOM 2945 C CD  . ARG C 1 176 ? 139.697 131.531 155.723 1.00 48.82  ? 266 ARG C CD  1 
ATOM 2946 N NE  . ARG C 1 176 ? 138.521 132.056 155.056 1.00 48.82  ? 266 ARG C NE  1 
ATOM 2947 C CZ  . ARG C 1 176 ? 138.516 133.193 154.379 1.00 48.82  ? 266 ARG C CZ  1 
ATOM 2948 N NH1 . ARG C 1 176 ? 139.627 133.903 154.284 1.00 48.82  ? 266 ARG C NH1 1 
ATOM 2949 N NH2 . ARG C 1 176 ? 137.409 133.619 153.798 1.00 48.82  ? 266 ARG C NH2 1 
ATOM 2950 N N   . ASN C 1 177 ? 136.257 129.203 156.342 1.00 51.42  ? 267 ASN C N   1 
ATOM 2951 C CA  . ASN C 1 177 ? 135.419 129.778 157.384 1.00 51.42  ? 267 ASN C CA  1 
ATOM 2952 C C   . ASN C 1 177 ? 134.776 128.691 158.226 1.00 51.42  ? 267 ASN C C   1 
ATOM 2953 O O   . ASN C 1 177 ? 134.532 128.896 159.416 1.00 51.42  ? 267 ASN C O   1 
ATOM 2954 C CB  . ASN C 1 177 ? 134.370 130.712 156.776 1.00 51.42  ? 267 ASN C CB  1 
ATOM 2955 C CG  . ASN C 1 177 ? 133.940 131.815 157.738 1.00 51.42  ? 267 ASN C CG  1 
ATOM 2956 O OD1 . ASN C 1 177 ? 133.925 131.629 158.947 1.00 51.42  ? 267 ASN C OD1 1 
ATOM 2957 N ND2 . ASN C 1 177 ? 133.637 132.981 157.199 1.00 51.42  ? 267 ASN C ND2 1 
ATOM 2958 N N   . ASN C 1 178 ? 134.544 127.512 157.652 1.00 56.04  ? 268 ASN C N   1 
ATOM 2959 C CA  . ASN C 1 178 ? 133.977 126.444 158.464 1.00 56.04  ? 268 ASN C CA  1 
ATOM 2960 C C   . ASN C 1 178 ? 135.019 125.850 159.398 1.00 56.04  ? 268 ASN C C   1 
ATOM 2961 O O   . ASN C 1 178 ? 134.716 125.569 160.566 1.00 56.04  ? 268 ASN C O   1 
ATOM 2962 C CB  . ASN C 1 178 ? 133.362 125.366 157.584 1.00 56.04  ? 268 ASN C CB  1 
ATOM 2963 C CG  . ASN C 1 178 ? 131.861 125.455 157.535 1.00 56.04  ? 268 ASN C CG  1 
ATOM 2964 O OD1 . ASN C 1 178 ? 131.157 124.653 158.142 1.00 56.04  ? 268 ASN C OD1 1 
ATOM 2965 N ND2 . ASN C 1 178 ? 131.357 126.451 156.814 1.00 56.04  ? 268 ASN C ND2 1 
ATOM 2966 N N   . ASN C 1 179 ? 136.249 125.640 158.916 1.00 62.29  ? 269 ASN C N   1 
ATOM 2967 C CA  . ASN C 1 179 ? 137.292 125.275 159.869 1.00 62.29  ? 269 ASN C CA  1 
ATOM 2968 C C   . ASN C 1 179 ? 137.359 126.284 160.989 1.00 62.29  ? 269 ASN C C   1 
ATOM 2969 O O   . ASN C 1 179 ? 137.661 125.934 162.134 1.00 62.29  ? 269 ASN C O   1 
ATOM 2970 C CB  . ASN C 1 179 ? 138.663 125.151 159.214 1.00 62.29  ? 269 ASN C CB  1 
ATOM 2971 C CG  . ASN C 1 179 ? 138.966 123.741 158.746 1.00 62.29  ? 269 ASN C CG  1 
ATOM 2972 O OD1 . ASN C 1 179 ? 138.583 122.775 159.393 1.00 62.29  ? 269 ASN C OD1 1 
ATOM 2973 N ND2 . ASN C 1 179 ? 139.702 123.617 157.654 1.00 62.29  ? 269 ASN C ND2 1 
ATOM 2974 N N   . MET C 1 180 ? 137.087 127.547 160.678 1.00 65.68  ? 270 MET C N   1 
ATOM 2975 C CA  . MET C 1 180 ? 137.168 128.574 161.705 1.00 65.68  ? 270 MET C CA  1 
ATOM 2976 C C   . MET C 1 180 ? 136.239 128.275 162.876 1.00 65.68  ? 270 MET C C   1 
ATOM 2977 O O   . MET C 1 180 ? 136.707 128.127 164.010 1.00 65.68  ? 270 MET C O   1 
ATOM 2978 C CB  . MET C 1 180 ? 136.862 129.942 161.108 1.00 65.68  ? 270 MET C CB  1 
ATOM 2979 C CG  . MET C 1 180 ? 138.073 130.667 160.577 1.00 65.68  ? 270 MET C CG  1 
ATOM 2980 S SD  . MET C 1 180 ? 137.640 132.295 159.939 1.00 65.68  ? 270 MET C SD  1 
ATOM 2981 C CE  . MET C 1 180 ? 138.318 133.365 161.196 1.00 65.68  ? 270 MET C CE  1 
ATOM 2982 N N   . ILE C 1 181 ? 134.930 128.170 162.631 1.00 59.43  ? 271 ILE C N   1 
ATOM 2983 C CA  . ILE C 1 181 ? 134.022 127.824 163.717 1.00 59.43  ? 271 ILE C CA  1 
ATOM 2984 C C   . ILE C 1 181 ? 134.446 126.519 164.353 1.00 59.43  ? 271 ILE C C   1 
ATOM 2985 O O   . ILE C 1 181 ? 134.516 126.406 165.582 1.00 59.43  ? 271 ILE C O   1 
ATOM 2986 C CB  . ILE C 1 181 ? 132.574 127.727 163.221 1.00 59.43  ? 271 ILE C CB  1 
ATOM 2987 C CG1 . ILE C 1 181 ? 132.014 129.097 162.892 1.00 59.43  ? 271 ILE C CG1 1 
ATOM 2988 C CG2 . ILE C 1 181 ? 131.721 127.107 164.284 1.00 59.43  ? 271 ILE C CG2 1 
ATOM 2989 C CD1 . ILE C 1 181 ? 130.678 129.011 162.209 1.00 59.43  ? 271 ILE C CD1 1 
ATOM 2990 N N   . MET C 1 182 ? 134.747 125.517 163.528 1.00 71.75  ? 272 MET C N   1 
ATOM 2991 C CA  . MET C 1 182 ? 135.074 124.204 164.059 1.00 71.75  ? 272 MET C CA  1 
ATOM 2992 C C   . MET C 1 182 ? 136.215 124.276 165.059 1.00 71.75  ? 272 MET C C   1 
ATOM 2993 O O   . MET C 1 182 ? 136.269 123.485 166.007 1.00 71.75  ? 272 MET C O   1 
ATOM 2994 C CB  . MET C 1 182 ? 135.416 123.258 162.917 1.00 71.75  ? 272 MET C CB  1 
ATOM 2995 C CG  . MET C 1 182 ? 134.318 122.276 162.624 1.00 71.75  ? 272 MET C CG  1 
ATOM 2996 S SD  . MET C 1 182 ? 134.132 121.221 164.061 1.00 71.75  ? 272 MET C SD  1 
ATOM 2997 C CE  . MET C 1 182 ? 132.813 120.151 163.530 1.00 71.75  ? 272 MET C CE  1 
ATOM 2998 N N   . ARG C 1 183 ? 137.131 125.223 164.873 1.00 78.27  ? 273 ARG C N   1 
ATOM 2999 C CA  . ARG C 1 183 ? 138.261 125.334 165.782 1.00 78.27  ? 273 ARG C CA  1 
ATOM 3000 C C   . ARG C 1 183 ? 137.840 125.700 167.196 1.00 78.27  ? 273 ARG C C   1 
ATOM 3001 O O   . ARG C 1 183 ? 138.574 125.398 168.142 1.00 78.27  ? 273 ARG C O   1 
ATOM 3002 C CB  . ARG C 1 183 ? 139.245 126.365 165.257 1.00 78.27  ? 273 ARG C CB  1 
ATOM 3003 C CG  . ARG C 1 183 ? 140.523 126.444 166.046 1.00 78.27  ? 273 ARG C CG  1 
ATOM 3004 C CD  . ARG C 1 183 ? 141.324 125.185 165.890 1.00 78.27  ? 273 ARG C CD  1 
ATOM 3005 N NE  . ARG C 1 183 ? 142.272 125.031 166.978 1.00 78.27  ? 273 ARG C NE  1 
ATOM 3006 C CZ  . ARG C 1 183 ? 141.936 124.622 168.190 1.00 78.27  ? 273 ARG C CZ  1 
ATOM 3007 N NH1 . ARG C 1 183 ? 140.674 124.326 168.456 1.00 78.27  ? 273 ARG C NH1 1 
ATOM 3008 N NH2 . ARG C 1 183 ? 142.858 124.504 169.133 1.00 78.27  ? 273 ARG C NH2 1 
ATOM 3009 N N   . SER C 1 184 ? 136.673 126.322 167.365 1.00 74.18  ? 274 SER C N   1 
ATOM 3010 C CA  . SER C 1 184 ? 136.270 126.782 168.688 1.00 74.18  ? 274 SER C CA  1 
ATOM 3011 C C   . SER C 1 184 ? 135.958 125.632 169.633 1.00 74.18  ? 274 SER C C   1 
ATOM 3012 O O   . SER C 1 184 ? 135.848 125.845 170.844 1.00 74.18  ? 274 SER C O   1 
ATOM 3013 C CB  . SER C 1 184 ? 135.062 127.703 168.582 1.00 74.18  ? 274 SER C CB  1 
ATOM 3014 O OG  . SER C 1 184 ? 135.375 128.995 169.062 1.00 74.18  ? 274 SER C OG  1 
ATOM 3015 N N   . PHE C 1 185 ? 135.801 124.422 169.115 1.00 83.34  ? 275 PHE C N   1 
ATOM 3016 C CA  . PHE C 1 185 ? 135.415 123.291 169.943 1.00 83.34  ? 275 PHE C CA  1 
ATOM 3017 C C   . PHE C 1 185 ? 136.505 122.245 170.085 1.00 83.34  ? 275 PHE C C   1 
ATOM 3018 O O   . PHE C 1 185 ? 136.186 121.078 170.317 1.00 83.34  ? 275 PHE C O   1 
ATOM 3019 C CB  . PHE C 1 185 ? 134.155 122.645 169.382 1.00 83.34  ? 275 PHE C CB  1 
ATOM 3020 C CG  . PHE C 1 185 ? 132.939 123.468 169.578 1.00 83.34  ? 275 PHE C CG  1 
ATOM 3021 C CD1 . PHE C 1 185 ? 132.294 123.476 170.793 1.00 83.34  ? 275 PHE C CD1 1 
ATOM 3022 C CD2 . PHE C 1 185 ? 132.457 124.262 168.565 1.00 83.34  ? 275 PHE C CD2 1 
ATOM 3023 C CE1 . PHE C 1 185 ? 131.179 124.242 170.988 1.00 83.34  ? 275 PHE C CE1 1 
ATOM 3024 C CE2 . PHE C 1 185 ? 131.339 125.032 168.753 1.00 83.34  ? 275 PHE C CE2 1 
ATOM 3025 C CZ  . PHE C 1 185 ? 130.700 125.023 169.967 1.00 83.34  ? 275 PHE C CZ  1 
ATOM 3026 N N   . ARG C 1 186 ? 137.772 122.631 169.965 1.00 88.18  ? 276 ARG C N   1 
ATOM 3027 C CA  . ARG C 1 186 ? 138.886 121.687 170.027 1.00 88.18  ? 276 ARG C CA  1 
ATOM 3028 C C   . ARG C 1 186 ? 138.716 120.553 169.023 1.00 88.18  ? 276 ARG C C   1 
ATOM 3029 O O   . ARG C 1 186 ? 139.058 119.401 169.304 1.00 88.18  ? 276 ARG C O   1 
ATOM 3030 C CB  . ARG C 1 186 ? 139.024 121.118 171.440 1.00 50.00  ? 276 ARG C CB  1 
ATOM 3031 C CG  . ARG C 1 186 ? 139.445 122.141 172.483 1.00 50.00  ? 276 ARG C CG  1 
ATOM 3032 C CD  . ARG C 1 186 ? 139.629 121.567 173.878 1.00 50.00  ? 276 ARG C CD  1 
ATOM 3033 N NE  . ARG C 1 186 ? 139.965 122.598 174.855 1.00 50.00  ? 276 ARG C NE  1 
ATOM 3034 C CZ  . ARG C 1 186 ? 140.065 122.385 176.159 1.00 50.00  ? 276 ARG C CZ  1 
ATOM 3035 N NH1 . ARG C 1 186 ? 139.859 121.170 176.653 1.00 50.00  ? 276 ARG C NH1 1 
ATOM 3036 N NH2 . ARG C 1 186 ? 140.374 123.384 176.976 1.00 50.00  ? 276 ARG C NH2 1 
ATOM 3037 N N   . GLN C 1 187 ? 138.174 120.885 167.856 1.00 79.73  ? 277 GLN C N   1 
ATOM 3038 C CA  . GLN C 1 187 ? 137.975 119.883 166.821 1.00 79.73  ? 277 GLN C CA  1 
ATOM 3039 C C   . GLN C 1 187 ? 139.013 120.058 165.729 1.00 79.73  ? 277 GLN C C   1 
ATOM 3040 O O   . GLN C 1 187 ? 139.361 121.183 165.372 1.00 79.73  ? 277 GLN C O   1 
ATOM 3041 C CB  . GLN C 1 187 ? 136.579 120.010 166.221 1.00 79.73  ? 277 GLN C CB  1 
ATOM 3042 C CG  . GLN C 1 187 ? 135.475 120.184 167.246 1.00 79.73  ? 277 GLN C CG  1 
ATOM 3043 C CD  . GLN C 1 187 ? 135.319 118.982 168.156 1.00 79.73  ? 277 GLN C CD  1 
ATOM 3044 O OE1 . GLN C 1 187 ? 135.845 117.903 167.881 1.00 79.73  ? 277 GLN C OE1 1 
ATOM 3045 N NE2 . GLN C 1 187 ? 134.583 119.162 169.246 1.00 79.73  ? 277 GLN C NE2 1 
ATOM 3046 N N   . PRO C 1 188 ? 139.510 118.940 165.185 1.00 78.54  ? 278 PRO C N   1 
ATOM 3047 C CA  . PRO C 1 188 ? 140.538 119.025 164.150 1.00 78.54  ? 278 PRO C CA  1 
ATOM 3048 C C   . PRO C 1 188 ? 139.997 119.696 162.901 1.00 78.54  ? 278 PRO C C   1 
ATOM 3049 O O   . PRO C 1 188 ? 138.814 119.609 162.577 1.00 78.54  ? 278 PRO C O   1 
ATOM 3050 C CB  . PRO C 1 188 ? 140.896 117.561 163.880 1.00 78.54  ? 278 PRO C CB  1 
ATOM 3051 C CG  . PRO C 1 188 ? 140.333 116.799 165.041 1.00 78.54  ? 278 PRO C CG  1 
ATOM 3052 C CD  . PRO C 1 188 ? 139.133 117.554 165.480 1.00 78.54  ? 278 PRO C CD  1 
ATOM 3053 N N   . ILE C 1 189 ? 140.895 120.373 162.195 1.00 67.43  ? 279 ILE C N   1 
ATOM 3054 C CA  . ILE C 1 189 ? 140.557 121.049 160.950 1.00 67.43  ? 279 ILE C CA  1 
ATOM 3055 C C   . ILE C 1 189 ? 140.636 120.076 159.792 1.00 67.43  ? 279 ILE C C   1 
ATOM 3056 O O   . ILE C 1 189 ? 141.150 118.964 159.933 1.00 67.43  ? 279 ILE C O   1 
ATOM 3057 C CB  . ILE C 1 189 ? 141.489 122.234 160.703 1.00 67.43  ? 279 ILE C CB  1 
ATOM 3058 C CG1 . ILE C 1 189 ? 142.912 121.798 161.020 1.00 67.43  ? 279 ILE C CG1 1 
ATOM 3059 C CG2 . ILE C 1 189 ? 141.059 123.408 161.526 1.00 67.43  ? 279 ILE C CG2 1 
ATOM 3060 C CD1 . ILE C 1 189 ? 143.931 122.873 160.869 1.00 67.43  ? 279 ILE C CD1 1 
ATOM 3061 N N   . THR C 1 190 ? 140.135 120.492 158.639 1.00 60.06  ? 280 THR C N   1 
ATOM 3062 C CA  . THR C 1 190 ? 140.167 119.680 157.439 1.00 60.06  ? 280 THR C CA  1 
ATOM 3063 C C   . THR C 1 190 ? 141.050 120.339 156.393 1.00 60.06  ? 280 THR C C   1 
ATOM 3064 O O   . THR C 1 190 ? 141.387 121.518 156.489 1.00 60.06  ? 280 THR C O   1 
ATOM 3065 C CB  . THR C 1 190 ? 138.764 119.492 156.876 1.00 60.06  ? 280 THR C CB  1 
ATOM 3066 O OG1 . THR C 1 190 ? 138.436 120.625 156.067 1.00 60.06  ? 280 THR C OG1 1 
ATOM 3067 C CG2 . THR C 1 190 ? 137.765 119.399 158.004 1.00 60.06  ? 280 THR C CG2 1 
ATOM 3068 N N   . GLU C 1 191 ? 141.410 119.565 155.378 1.00 59.61  ? 281 GLU C N   1 
ATOM 3069 C CA  . GLU C 1 191 ? 142.262 120.051 154.298 1.00 59.61  ? 281 GLU C CA  1 
ATOM 3070 C C   . GLU C 1 191 ? 141.519 121.149 153.550 1.00 59.61  ? 281 GLU C C   1 
ATOM 3071 O O   . GLU C 1 191 ? 140.311 121.318 153.707 1.00 59.61  ? 281 GLU C O   1 
ATOM 3072 C CB  . GLU C 1 191 ? 142.644 118.899 153.377 1.00 59.61  ? 281 GLU C CB  1 
ATOM 3073 C CG  . GLU C 1 191 ? 143.794 119.182 152.415 1.00 59.61  ? 281 GLU C CG  1 
ATOM 3074 C CD  . GLU C 1 191 ? 144.176 117.970 151.571 1.00 59.61  ? 281 GLU C CD  1 
ATOM 3075 O OE1 . GLU C 1 191 ? 143.509 116.920 151.689 1.00 59.61  ? 281 GLU C OE1 1 
ATOM 3076 O OE2 . GLU C 1 191 ? 145.147 118.066 150.791 1.00 59.61  ? 281 GLU C OE2 1 
ATOM 3077 N N   . VAL C 1 192 ? 142.239 121.912 152.748 1.00 44.78  ? 282 VAL C N   1 
ATOM 3078 C CA  . VAL C 1 192 ? 141.644 123.073 152.083 1.00 44.78  ? 282 VAL C CA  1 
ATOM 3079 C C   . VAL C 1 192 ? 142.084 123.100 150.633 1.00 44.78  ? 282 VAL C C   1 
ATOM 3080 O O   . VAL C 1 192 ? 143.260 122.842 150.348 1.00 44.78  ? 282 VAL C O   1 
ATOM 3081 C CB  . VAL C 1 192 ? 142.062 124.340 152.803 1.00 44.78  ? 282 VAL C CB  1 
ATOM 3082 C CG1 . VAL C 1 192 ? 142.105 125.493 151.851 1.00 44.78  ? 282 VAL C CG1 1 
ATOM 3083 C CG2 . VAL C 1 192 ? 141.093 124.612 153.908 1.00 44.78  ? 282 VAL C CG2 1 
ATOM 3084 N N   . PRO C 1 193 ? 141.216 123.425 149.689 1.00 54.83  ? 283 PRO C N   1 
ATOM 3085 C CA  . PRO C 1 193 ? 141.618 123.390 148.287 1.00 54.83  ? 283 PRO C CA  1 
ATOM 3086 C C   . PRO C 1 193 ? 142.495 124.579 147.960 1.00 54.83  ? 283 PRO C C   1 
ATOM 3087 O O   . PRO C 1 193 ? 142.609 125.522 148.742 1.00 54.83  ? 283 PRO C O   1 
ATOM 3088 C CB  . PRO C 1 193 ? 140.291 123.463 147.527 1.00 54.83  ? 283 PRO C CB  1 
ATOM 3089 C CG  . PRO C 1 193 ? 139.227 123.433 148.572 1.00 54.83  ? 283 PRO C CG  1 
ATOM 3090 C CD  . PRO C 1 193 ? 139.846 123.913 149.834 1.00 54.83  ? 283 PRO C CD  1 
ATOM 3091 N N   . PHE C 1 194 ? 143.110 124.526 146.787 1.00 59.26  ? 284 PHE C N   1 
ATOM 3092 C CA  . PHE C 1 194 ? 143.923 125.633 146.327 1.00 59.26  ? 284 PHE C CA  1 
ATOM 3093 C C   . PHE C 1 194 ? 143.109 126.558 145.432 1.00 59.26  ? 284 PHE C C   1 
ATOM 3094 O O   . PHE C 1 194 ? 142.099 126.176 144.838 1.00 59.26  ? 284 PHE C O   1 
ATOM 3095 C CB  . PHE C 1 194 ? 145.149 125.126 145.579 1.00 59.26  ? 284 PHE C CB  1 
ATOM 3096 C CG  . PHE C 1 194 ? 146.269 124.726 146.473 1.00 59.26  ? 284 PHE C CG  1 
ATOM 3097 C CD1 . PHE C 1 194 ? 146.307 125.158 147.775 1.00 59.26  ? 284 PHE C CD1 1 
ATOM 3098 C CD2 . PHE C 1 194 ? 147.289 123.926 146.011 1.00 59.26  ? 284 PHE C CD2 1 
ATOM 3099 C CE1 . PHE C 1 194 ? 147.336 124.795 148.597 1.00 59.26  ? 284 PHE C CE1 1 
ATOM 3100 C CE2 . PHE C 1 194 ? 148.319 123.569 146.830 1.00 59.26  ? 284 PHE C CE2 1 
ATOM 3101 C CZ  . PHE C 1 194 ? 148.341 123.999 148.124 1.00 59.26  ? 284 PHE C CZ  1 
ATOM 3102 N N   . PHE C 1 195 ? 143.599 127.786 145.309 1.00 55.70  ? 285 PHE C N   1 
ATOM 3103 C CA  . PHE C 1 195 ? 142.946 128.849 144.564 1.00 55.70  ? 285 PHE C CA  1 
ATOM 3104 C C   . PHE C 1 195 ? 142.576 128.423 143.148 1.00 55.70  ? 285 PHE C C   1 
ATOM 3105 O O   . PHE C 1 195 ? 141.758 129.073 142.496 1.00 55.70  ? 285 PHE C O   1 
ATOM 3106 C CB  . PHE C 1 195 ? 143.867 130.065 144.560 1.00 55.70  ? 285 PHE C CB  1 
ATOM 3107 C CG  . PHE C 1 195 ? 143.650 130.991 143.418 1.00 55.70  ? 285 PHE C CG  1 
ATOM 3108 C CD1 . PHE C 1 195 ? 144.535 131.014 142.359 1.00 55.70  ? 285 PHE C CD1 1 
ATOM 3109 C CD2 . PHE C 1 195 ? 142.581 131.859 143.408 1.00 55.70  ? 285 PHE C CD2 1 
ATOM 3110 C CE1 . PHE C 1 195 ? 144.348 131.871 141.300 1.00 55.70  ? 285 PHE C CE1 1 
ATOM 3111 C CE2 . PHE C 1 195 ? 142.391 132.720 142.351 1.00 55.70  ? 285 PHE C CE2 1 
ATOM 3112 C CZ  . PHE C 1 195 ? 143.276 132.725 141.296 1.00 55.70  ? 285 PHE C CZ  1 
ATOM 3113 N N   . ASN C 1 196 ? 143.142 127.322 142.664 1.00 52.37  ? 286 ASN C N   1 
ATOM 3114 C CA  . ASN C 1 196 ? 142.822 126.806 141.342 1.00 52.37  ? 286 ASN C CA  1 
ATOM 3115 C C   . ASN C 1 196 ? 142.028 125.512 141.393 1.00 52.37  ? 286 ASN C C   1 
ATOM 3116 O O   . ASN C 1 196 ? 141.638 125.000 140.342 1.00 52.37  ? 286 ASN C O   1 
ATOM 3117 C CB  . ASN C 1 196 ? 144.099 126.586 140.546 1.00 52.37  ? 286 ASN C CB  1 
ATOM 3118 C CG  . ASN C 1 196 ? 144.900 125.427 141.072 1.00 52.37  ? 286 ASN C CG  1 
ATOM 3119 O OD1 . ASN C 1 196 ? 144.920 125.179 142.273 1.00 52.37  ? 286 ASN C OD1 1 
ATOM 3120 N ND2 . ASN C 1 196 ? 145.574 124.713 140.183 1.00 52.37  ? 286 ASN C ND2 1 
ATOM 3121 N N   . GLY C 1 197 ? 141.789 124.962 142.582 1.00 58.46  ? 287 GLY C N   1 
ATOM 3122 C CA  . GLY C 1 197 ? 140.887 123.838 142.742 1.00 58.46  ? 287 GLY C CA  1 
ATOM 3123 C C   . GLY C 1 197 ? 141.504 122.517 143.158 1.00 58.46  ? 287 GLY C C   1 
ATOM 3124 O O   . GLY C 1 197 ? 140.899 121.805 143.970 1.00 58.46  ? 287 GLY C O   1 
ATOM 3125 N N   . ASP C 1 198 ? 142.676 122.165 142.641 1.00 67.17  ? 288 ASP C N   1 
ATOM 3126 C CA  . ASP C 1 198 ? 143.304 120.886 142.927 1.00 67.17  ? 288 ASP C CA  1 
ATOM 3127 C C   . ASP C 1 198 ? 143.504 120.709 144.422 1.00 67.17  ? 288 ASP C C   1 
ATOM 3128 O O   . ASP C 1 198 ? 143.449 121.662 145.198 1.00 67.17  ? 288 ASP C O   1 
ATOM 3129 C CB  . ASP C 1 198 ? 144.660 120.779 142.238 1.00 67.17  ? 288 ASP C CB  1 
ATOM 3130 C CG  . ASP C 1 198 ? 144.614 121.220 140.802 1.00 67.17  ? 288 ASP C CG  1 
ATOM 3131 O OD1 . ASP C 1 198 ? 143.624 120.895 140.120 1.00 67.17  ? 288 ASP C OD1 1 
ATOM 3132 O OD2 . ASP C 1 198 ? 145.568 121.890 140.355 1.00 67.17  ? 288 ASP C OD2 1 
ATOM 3133 N N   . ILE C 1 199 ? 143.729 119.469 144.825 1.00 66.78  ? 289 ILE C N   1 
ATOM 3134 C CA  . ILE C 1 199 ? 144.205 119.213 146.177 1.00 66.78  ? 289 ILE C CA  1 
ATOM 3135 C C   . ILE C 1 199 ? 145.688 119.541 146.161 1.00 66.78  ? 289 ILE C C   1 
ATOM 3136 O O   . ILE C 1 199 ? 146.321 119.457 145.100 1.00 66.78  ? 289 ILE C O   1 
ATOM 3137 C CB  . ILE C 1 199 ? 143.897 117.774 146.617 1.00 66.78  ? 289 ILE C CB  1 
ATOM 3138 C CG1 . ILE C 1 199 ? 142.872 117.785 147.758 1.00 66.78  ? 289 ILE C CG1 1 
ATOM 3139 C CG2 . ILE C 1 199 ? 145.155 117.047 147.040 1.00 66.78  ? 289 ILE C CG2 1 
ATOM 3140 C CD1 . ILE C 1 199 ? 141.553 117.111 147.412 1.00 66.78  ? 289 ILE C CD1 1 
ATOM 3141 N N   . PRO C 1 200 ? 146.269 119.966 147.280 1.00 77.77  ? 290 PRO C N   1 
ATOM 3142 C CA  . PRO C 1 200 ? 147.683 120.345 147.289 1.00 77.77  ? 290 PRO C CA  1 
ATOM 3143 C C   . PRO C 1 200 ? 148.581 119.213 146.821 1.00 77.77  ? 290 PRO C C   1 
ATOM 3144 O O   . PRO C 1 200 ? 148.134 118.085 146.608 1.00 77.77  ? 290 PRO C O   1 
ATOM 3145 C CB  . PRO C 1 200 ? 147.944 120.683 148.758 1.00 77.77  ? 290 PRO C CB  1 
ATOM 3146 C CG  . PRO C 1 200 ? 146.635 121.040 149.295 1.00 77.77  ? 290 PRO C CG  1 
ATOM 3147 C CD  . PRO C 1 200 ? 145.634 120.194 148.583 1.00 77.77  ? 290 PRO C CD  1 
ATOM 3148 N N   . ASP C 1 201 ? 149.861 119.523 146.651 1.00 101.26 ? 291 ASP C N   1 
ATOM 3149 C CA  . ASP C 1 201 ? 150.812 118.490 146.288 1.00 101.26 ? 291 ASP C CA  1 
ATOM 3150 C C   . ASP C 1 201 ? 150.805 117.397 147.359 1.00 101.26 ? 291 ASP C C   1 
ATOM 3151 O O   . ASP C 1 201 ? 151.176 117.669 148.507 1.00 101.26 ? 291 ASP C O   1 
ATOM 3152 C CB  . ASP C 1 201 ? 152.217 119.049 146.127 1.00 101.26 ? 291 ASP C CB  1 
ATOM 3153 C CG  . ASP C 1 201 ? 153.190 118.010 145.620 1.00 101.26 ? 291 ASP C CG  1 
ATOM 3154 O OD1 . ASP C 1 201 ? 153.608 118.110 144.448 1.00 101.26 ? 291 ASP C OD1 1 
ATOM 3155 O OD2 . ASP C 1 201 ? 153.514 117.077 146.380 1.00 101.26 ? 291 ASP C OD2 1 
ATOM 3156 N N   . PRO C 1 202 ? 150.405 116.177 147.018 1.00 102.46 ? 292 PRO C N   1 
ATOM 3157 C CA  . PRO C 1 202 ? 150.213 115.153 148.059 1.00 102.46 ? 292 PRO C CA  1 
ATOM 3158 C C   . PRO C 1 202 ? 151.477 114.809 148.813 1.00 102.46 ? 292 PRO C C   1 
ATOM 3159 O O   . PRO C 1 202 ? 151.395 114.138 149.850 1.00 102.46 ? 292 PRO C O   1 
ATOM 3160 C CB  . PRO C 1 202 ? 149.682 113.949 147.273 1.00 102.46 ? 292 PRO C CB  1 
ATOM 3161 C CG  . PRO C 1 202 ? 149.168 114.526 145.984 1.00 102.46 ? 292 PRO C CG  1 
ATOM 3162 C CD  . PRO C 1 202 ? 150.070 115.673 145.681 1.00 102.46 ? 292 PRO C CD  1 
ATOM 3163 N N   . ASN C 1 203 ? 152.641 115.233 148.336 1.00 112.50 ? 293 ASN C N   1 
ATOM 3164 C CA  . ASN C 1 203 ? 153.839 115.196 149.157 1.00 112.50 ? 293 ASN C CA  1 
ATOM 3165 C C   . ASN C 1 203 ? 153.843 116.285 150.217 1.00 112.50 ? 293 ASN C C   1 
ATOM 3166 O O   . ASN C 1 203 ? 154.613 116.197 151.178 1.00 112.50 ? 293 ASN C O   1 
ATOM 3167 C CB  . ASN C 1 203 ? 155.089 115.339 148.289 1.00 112.50 ? 293 ASN C CB  1 
ATOM 3168 C CG  . ASN C 1 203 ? 156.364 115.271 149.093 1.00 112.50 ? 293 ASN C CG  1 
ATOM 3169 O OD1 . ASN C 1 203 ? 156.445 114.557 150.091 1.00 112.50 ? 293 ASN C OD1 1 
ATOM 3170 N ND2 . ASN C 1 203 ? 157.359 116.049 148.687 1.00 112.50 ? 293 ASN C ND2 1 
ATOM 3171 N N   . LEU C 1 204 ? 152.991 117.292 150.083 1.00 102.56 ? 294 LEU C N   1 
ATOM 3172 C CA  . LEU C 1 204 ? 153.010 118.375 151.042 1.00 102.56 ? 294 LEU C CA  1 
ATOM 3173 C C   . LEU C 1 204 ? 152.124 118.021 152.231 1.00 102.56 ? 294 LEU C C   1 
ATOM 3174 O O   . LEU C 1 204 ? 150.951 117.682 152.066 1.00 102.56 ? 294 LEU C O   1 
ATOM 3175 C CB  . LEU C 1 204 ? 152.553 119.675 150.402 1.00 102.56 ? 294 LEU C CB  1 
ATOM 3176 C CG  . LEU C 1 204 ? 153.606 120.439 149.588 1.00 102.56 ? 294 LEU C CG  1 
ATOM 3177 C CD1 . LEU C 1 204 ? 154.235 121.520 150.443 1.00 102.56 ? 294 LEU C CD1 1 
ATOM 3178 C CD2 . LEU C 1 204 ? 154.687 119.545 148.993 1.00 102.56 ? 294 LEU C CD2 1 
ATOM 3179 N N   . PRO C 1 205 ? 152.665 118.094 153.424 1.00 96.81  ? 295 PRO C N   1 
ATOM 3180 C CA  . PRO C 1 205 ? 152.002 117.486 154.581 1.00 96.81  ? 295 PRO C CA  1 
ATOM 3181 C C   . PRO C 1 205 ? 150.654 118.107 154.868 1.00 96.81  ? 295 PRO C C   1 
ATOM 3182 O O   . PRO C 1 205 ? 150.528 119.331 154.887 1.00 96.81  ? 295 PRO C O   1 
ATOM 3183 C CB  . PRO C 1 205 ? 152.986 117.742 155.729 1.00 96.81  ? 295 PRO C CB  1 
ATOM 3184 C CG  . PRO C 1 205 ? 154.254 118.211 155.074 1.00 96.81  ? 295 PRO C CG  1 
ATOM 3185 C CD  . PRO C 1 205 ? 153.857 118.858 153.802 1.00 96.81  ? 295 PRO C CD  1 
ATOM 3186 N N   . ARG C 1 206 ? 149.641 117.278 155.074 1.00 87.82  ? 296 ARG C N   1 
ATOM 3187 C CA  . ARG C 1 206 ? 148.321 117.782 155.430 1.00 87.82  ? 296 ARG C CA  1 
ATOM 3188 C C   . ARG C 1 206 ? 148.380 118.460 156.794 1.00 87.82  ? 296 ARG C C   1 
ATOM 3189 O O   . ARG C 1 206 ? 149.241 118.143 157.619 1.00 87.82  ? 296 ARG C O   1 
ATOM 3190 C CB  . ARG C 1 206 ? 147.305 116.650 155.411 1.00 87.82  ? 296 ARG C CB  1 
ATOM 3191 C CG  . ARG C 1 206 ? 146.878 116.260 154.013 1.00 87.82  ? 296 ARG C CG  1 
ATOM 3192 C CD  . ARG C 1 206 ? 146.465 114.807 153.938 1.00 87.82  ? 296 ARG C CD  1 
ATOM 3193 N NE  . ARG C 1 206 ? 145.694 114.541 152.731 1.00 87.82  ? 296 ARG C NE  1 
ATOM 3194 C CZ  . ARG C 1 206 ? 144.465 114.037 152.732 1.00 87.82  ? 296 ARG C CZ  1 
ATOM 3195 N NH1 . ARG C 1 206 ? 143.878 113.729 153.878 1.00 87.82  ? 296 ARG C NH1 1 
ATOM 3196 N NH2 . ARG C 1 206 ? 143.829 113.831 151.588 1.00 87.82  ? 296 ARG C NH2 1 
ATOM 3197 N N   . ILE C 1 207 ? 147.465 119.398 157.026 1.00 85.03  ? 297 ILE C N   1 
ATOM 3198 C CA  . ILE C 1 207 ? 147.546 120.315 158.157 1.00 85.03  ? 297 ILE C CA  1 
ATOM 3199 C C   . ILE C 1 207 ? 146.434 119.964 159.138 1.00 85.03  ? 297 ILE C C   1 
ATOM 3200 O O   . ILE C 1 207 ? 145.285 119.772 158.736 1.00 85.03  ? 297 ILE C O   1 
ATOM 3201 C CB  . ILE C 1 207 ? 147.428 121.763 157.689 1.00 85.03  ? 297 ILE C CB  1 
ATOM 3202 C CG1 . ILE C 1 207 ? 148.232 121.938 156.411 1.00 85.03  ? 297 ILE C CG1 1 
ATOM 3203 C CG2 . ILE C 1 207 ? 147.940 122.691 158.752 1.00 85.03  ? 297 ILE C CG2 1 
ATOM 3204 C CD1 . ILE C 1 207 ? 147.779 123.094 155.578 1.00 85.03  ? 297 ILE C CD1 1 
ATOM 3205 N N   . THR C 1 208 ? 146.759 119.890 160.427 1.00 94.00  ? 298 THR C N   1 
ATOM 3206 C CA  . THR C 1 208 ? 145.777 119.513 161.433 1.00 94.00  ? 298 THR C CA  1 
ATOM 3207 C C   . THR C 1 208 ? 145.707 120.463 162.608 1.00 94.00  ? 298 THR C C   1 
ATOM 3208 O O   . THR C 1 208 ? 144.645 120.579 163.224 1.00 94.00  ? 298 THR C O   1 
ATOM 3209 C CB  . THR C 1 208 ? 146.080 118.119 161.992 1.00 94.00  ? 298 THR C CB  1 
ATOM 3210 O OG1 . THR C 1 208 ? 147.328 118.159 162.693 1.00 94.00  ? 298 THR C OG1 1 
ATOM 3211 C CG2 . THR C 1 208 ? 146.166 117.103 160.875 1.00 94.00  ? 298 THR C CG2 1 
ATOM 3212 N N   . ARG C 1 209 ? 146.811 121.105 162.961 1.00 109.26 ? 299 ARG C N   1 
ATOM 3213 C CA  . ARG C 1 209 ? 146.834 122.026 164.078 1.00 109.26 ? 299 ARG C CA  1 
ATOM 3214 C C   . ARG C 1 209 ? 148.058 122.912 163.954 1.00 109.26 ? 299 ARG C C   1 
ATOM 3215 O O   . ARG C 1 209 ? 148.815 122.835 162.983 1.00 109.26 ? 299 ARG C O   1 
ATOM 3216 C CB  . ARG C 1 209 ? 146.802 121.275 165.407 1.00 109.26 ? 299 ARG C CB  1 
ATOM 3217 C CG  . ARG C 1 209 ? 147.573 119.983 165.404 1.00 109.26 ? 299 ARG C CG  1 
ATOM 3218 C CD  . ARG C 1 209 ? 147.231 119.197 166.646 1.00 109.26 ? 299 ARG C CD  1 
ATOM 3219 N NE  . ARG C 1 209 ? 145.787 119.156 166.863 1.00 109.26 ? 299 ARG C NE  1 
ATOM 3220 C CZ  . ARG C 1 209 ? 145.215 118.764 167.995 1.00 109.26 ? 299 ARG C CZ  1 
ATOM 3221 N NH1 . ARG C 1 209 ? 145.963 118.375 169.018 1.00 109.26 ? 299 ARG C NH1 1 
ATOM 3222 N NH2 . ARG C 1 209 ? 143.894 118.758 168.106 1.00 109.26 ? 299 ARG C NH2 1 
ATOM 3223 N N   . ILE C 1 210 ? 148.263 123.744 164.964 1.00 116.05 ? 300 ILE C N   1 
ATOM 3224 C CA  . ILE C 1 210 ? 149.156 124.872 164.781 1.00 116.05 ? 300 ILE C CA  1 
ATOM 3225 C C   . ILE C 1 210 ? 150.614 124.438 164.789 1.00 116.05 ? 300 ILE C C   1 
ATOM 3226 O O   . ILE C 1 210 ? 151.396 124.864 163.930 1.00 116.05 ? 300 ILE C O   1 
ATOM 3227 C CB  . ILE C 1 210 ? 148.856 125.932 165.848 1.00 116.05 ? 300 ILE C CB  1 
ATOM 3228 C CG1 . ILE C 1 210 ? 149.840 127.088 165.741 1.00 116.05 ? 300 ILE C CG1 1 
ATOM 3229 C CG2 . ILE C 1 210 ? 148.872 125.317 167.236 1.00 116.05 ? 300 ILE C CG2 1 
ATOM 3230 C CD1 . ILE C 1 210 ? 149.319 128.352 166.352 1.00 116.05 ? 300 ILE C CD1 1 
ATOM 3231 N N   . GLU C 1 211 ? 151.005 123.580 165.730 1.00 119.34 ? 301 GLU C N   1 
ATOM 3232 C CA  . GLU C 1 211 ? 152.398 123.154 165.800 1.00 119.34 ? 301 GLU C CA  1 
ATOM 3233 C C   . GLU C 1 211 ? 152.829 122.474 164.510 1.00 119.34 ? 301 GLU C C   1 
ATOM 3234 O O   . GLU C 1 211 ? 154.004 122.538 164.126 1.00 119.34 ? 301 GLU C O   1 
ATOM 3235 C CB  . GLU C 1 211 ? 152.589 122.226 166.996 1.00 119.34 ? 301 GLU C CB  1 
ATOM 3236 C CG  . GLU C 1 211 ? 151.931 120.867 166.842 1.00 119.34 ? 301 GLU C CG  1 
ATOM 3237 C CD  . GLU C 1 211 ? 150.455 120.889 167.181 1.00 119.34 ? 301 GLU C CD  1 
ATOM 3238 O OE1 . GLU C 1 211 ? 149.763 121.868 166.825 1.00 119.34 ? 301 GLU C OE1 1 
ATOM 3239 O OE2 . GLU C 1 211 ? 149.997 119.932 167.835 1.00 119.34 ? 301 GLU C OE2 1 
ATOM 3240 N N   . ASP C 1 212 ? 151.888 121.815 163.830 1.00 117.07 ? 302 ASP C N   1 
ATOM 3241 C CA  . ASP C 1 212 ? 152.173 121.273 162.509 1.00 117.07 ? 302 ASP C CA  1 
ATOM 3242 C C   . ASP C 1 212 ? 152.774 122.337 161.611 1.00 117.07 ? 302 ASP C C   1 
ATOM 3243 O O   . ASP C 1 212 ? 153.820 122.123 160.988 1.00 117.07 ? 302 ASP C O   1 
ATOM 3244 C CB  . ASP C 1 212 ? 150.900 120.706 161.889 1.00 117.07 ? 302 ASP C CB  1 
ATOM 3245 C CG  . ASP C 1 212 ? 151.111 120.221 160.469 1.00 117.07 ? 302 ASP C CG  1 
ATOM 3246 O OD1 . ASP C 1 212 ? 151.943 119.310 160.263 1.00 117.07 ? 302 ASP C OD1 1 
ATOM 3247 O OD2 . ASP C 1 212 ? 150.441 120.752 159.558 1.00 117.07 ? 302 ASP C OD2 1 
ATOM 3248 N N   . ILE C 1 213 ? 152.126 123.493 161.537 1.00 109.46 ? 303 ILE C N   1 
ATOM 3249 C CA  . ILE C 1 213 ? 152.714 124.607 160.814 1.00 109.46 ? 303 ILE C CA  1 
ATOM 3250 C C   . ILE C 1 213 ? 154.037 124.999 161.442 1.00 109.46 ? 303 ILE C C   1 
ATOM 3251 O O   . ILE C 1 213 ? 155.061 125.094 160.757 1.00 109.46 ? 303 ILE C O   1 
ATOM 3252 C CB  . ILE C 1 213 ? 151.739 125.792 160.786 1.00 109.46 ? 303 ILE C CB  1 
ATOM 3253 C CG1 . ILE C 1 213 ? 150.445 125.383 160.101 1.00 109.46 ? 303 ILE C CG1 1 
ATOM 3254 C CG2 . ILE C 1 213 ? 152.370 126.954 160.072 1.00 109.46 ? 303 ILE C CG2 1 
ATOM 3255 C CD1 . ILE C 1 213 ? 149.696 126.544 159.508 1.00 109.46 ? 303 ILE C CD1 1 
ATOM 3256 N N   . ASP C 1 214 ? 154.047 125.208 162.760 1.00 117.46 ? 304 ASP C N   1 
ATOM 3257 C CA  . ASP C 1 214 ? 155.225 125.766 163.414 1.00 117.46 ? 304 ASP C CA  1 
ATOM 3258 C C   . ASP C 1 214 ? 156.461 124.905 163.223 1.00 117.46 ? 304 ASP C C   1 
ATOM 3259 O O   . ASP C 1 214 ? 157.565 125.348 163.552 1.00 117.46 ? 304 ASP C O   1 
ATOM 3260 C CB  . ASP C 1 214 ? 154.970 125.966 164.907 1.00 117.46 ? 304 ASP C CB  1 
ATOM 3261 C CG  . ASP C 1 214 ? 155.770 127.123 165.484 1.00 117.46 ? 304 ASP C CG  1 
ATOM 3262 O OD1 . ASP C 1 214 ? 156.323 127.920 164.701 1.00 117.46 ? 304 ASP C OD1 1 
ATOM 3263 O OD2 . ASP C 1 214 ? 155.859 127.236 166.722 1.00 117.46 ? 304 ASP C OD2 1 
ATOM 3264 N N   . SER C 1 215 ? 156.299 123.689 162.713 1.00 118.62 ? 305 SER C N   1 
ATOM 3265 C CA  . SER C 1 215 ? 157.435 122.822 162.443 1.00 118.62 ? 305 SER C CA  1 
ATOM 3266 C C   . SER C 1 215 ? 157.807 122.767 160.971 1.00 118.62 ? 305 SER C C   1 
ATOM 3267 O O   . SER C 1 215 ? 158.746 122.049 160.613 1.00 118.62 ? 305 SER C O   1 
ATOM 3268 C CB  . SER C 1 215 ? 157.135 121.410 162.943 1.00 118.62 ? 305 SER C CB  1 
ATOM 3269 O OG  . SER C 1 215 ? 157.067 120.493 161.867 1.00 118.62 ? 305 SER C OG  1 
ATOM 3270 N N   . LEU C 1 216 ? 157.110 123.499 160.113 1.00 110.26 ? 306 LEU C N   1 
ATOM 3271 C CA  . LEU C 1 216 ? 157.274 123.312 158.681 1.00 110.26 ? 306 LEU C CA  1 
ATOM 3272 C C   . LEU C 1 216 ? 158.547 123.986 158.181 1.00 110.26 ? 306 LEU C C   1 
ATOM 3273 O O   . LEU C 1 216 ? 159.101 124.872 158.836 1.00 110.26 ? 306 LEU C O   1 
ATOM 3274 C CB  . LEU C 1 216 ? 156.059 123.868 157.947 1.00 110.26 ? 306 LEU C CB  1 
ATOM 3275 C CG  . LEU C 1 216 ? 155.968 123.540 156.461 1.00 110.26 ? 306 LEU C CG  1 
ATOM 3276 C CD1 . LEU C 1 216 ? 156.263 122.066 156.245 1.00 110.26 ? 306 LEU C CD1 1 
ATOM 3277 C CD2 . LEU C 1 216 ? 154.610 123.906 155.907 1.00 110.26 ? 306 LEU C CD2 1 
ATOM 3278 N N   . SER C 1 217 ? 159.017 123.548 157.013 1.00 110.86 ? 307 SER C N   1 
ATOM 3279 C CA  . SER C 1 217 ? 160.165 124.162 156.365 1.00 110.86 ? 307 SER C CA  1 
ATOM 3280 C C   . SER C 1 217 ? 159.755 125.439 155.642 1.00 110.86 ? 307 SER C C   1 
ATOM 3281 O O   . SER C 1 217 ? 158.592 125.643 155.285 1.00 110.86 ? 307 SER C O   1 
ATOM 3282 C CB  . SER C 1 217 ? 160.799 123.200 155.365 1.00 110.86 ? 307 SER C CB  1 
ATOM 3283 O OG  . SER C 1 217 ? 160.616 123.671 154.043 1.00 110.86 ? 307 SER C OG  1 
ATOM 3284 N N   . GLU C 1 218 ? 160.745 126.303 155.411 1.00 114.14 ? 308 GLU C N   1 
ATOM 3285 C CA  . GLU C 1 218 ? 160.464 127.615 154.842 1.00 114.14 ? 308 GLU C CA  1 
ATOM 3286 C C   . GLU C 1 218 ? 159.957 127.496 153.411 1.00 114.14 ? 308 GLU C C   1 
ATOM 3287 O O   . GLU C 1 218 ? 158.961 128.132 153.044 1.00 114.14 ? 308 GLU C O   1 
ATOM 3288 C CB  . GLU C 1 218 ? 161.718 128.499 154.965 1.00 114.14 ? 308 GLU C CB  1 
ATOM 3289 C CG  . GLU C 1 218 ? 161.946 129.699 154.010 1.00 114.14 ? 308 GLU C CG  1 
ATOM 3290 C CD  . GLU C 1 218 ? 161.901 129.371 152.528 1.00 114.14 ? 308 GLU C CD  1 
ATOM 3291 O OE1 . GLU C 1 218 ? 162.573 128.406 152.121 1.00 114.14 ? 308 GLU C OE1 1 
ATOM 3292 O OE2 . GLU C 1 218 ? 161.189 130.069 151.787 1.00 114.14 ? 308 GLU C OE2 1 
ATOM 3293 N N   . GLU C 1 219 ? 160.633 126.704 152.582 1.00 113.63 ? 309 GLU C N   1 
ATOM 3294 C CA  . GLU C 1 219 ? 160.191 126.573 151.200 1.00 113.63 ? 309 GLU C CA  1 
ATOM 3295 C C   . GLU C 1 219 ? 158.766 126.052 151.142 1.00 113.63 ? 309 GLU C C   1 
ATOM 3296 O O   . GLU C 1 219 ? 157.970 126.481 150.302 1.00 113.63 ? 309 GLU C O   1 
ATOM 3297 C CB  . GLU C 1 219 ? 161.139 125.666 150.423 1.00 113.63 ? 309 GLU C CB  1 
ATOM 3298 C CG  . GLU C 1 219 ? 161.506 124.396 151.153 1.00 113.63 ? 309 GLU C CG  1 
ATOM 3299 C CD  . GLU C 1 219 ? 160.468 123.311 150.993 1.00 113.63 ? 309 GLU C CD  1 
ATOM 3300 O OE1 . GLU C 1 219 ? 159.639 123.410 150.067 1.00 113.63 ? 309 GLU C OE1 1 
ATOM 3301 O OE2 . GLU C 1 219 ? 160.468 122.371 151.811 1.00 113.63 ? 309 GLU C OE2 1 
ATOM 3302 N N   . ASN C 1 220 ? 158.422 125.136 152.042 1.00 104.58 ? 310 ASN C N   1 
ATOM 3303 C CA  . ASN C 1 220 ? 157.056 124.646 152.088 1.00 104.58 ? 310 ASN C CA  1 
ATOM 3304 C C   . ASN C 1 220 ? 156.101 125.751 152.492 1.00 104.58 ? 310 ASN C C   1 
ATOM 3305 O O   . ASN C 1 220 ? 154.972 125.821 151.994 1.00 104.58 ? 310 ASN C O   1 
ATOM 3306 C CB  . ASN C 1 220 ? 156.958 123.473 153.051 1.00 104.58 ? 310 ASN C CB  1 
ATOM 3307 C CG  . ASN C 1 220 ? 157.519 122.207 152.471 1.00 104.58 ? 310 ASN C CG  1 
ATOM 3308 O OD1 . ASN C 1 220 ? 157.394 121.956 151.274 1.00 104.58 ? 310 ASN C OD1 1 
ATOM 3309 N ND2 . ASN C 1 220 ? 158.138 121.394 153.313 1.00 104.58 ? 310 ASN C ND2 1 
ATOM 3310 N N   . CYS C 1 221 ? 156.529 126.611 153.413 1.00 101.63 ? 311 CYS C N   1 
ATOM 3311 C CA  . CYS C 1 221 ? 155.710 127.759 153.770 1.00 101.63 ? 311 CYS C CA  1 
ATOM 3312 C C   . CYS C 1 221 ? 155.414 128.604 152.544 1.00 101.63 ? 311 CYS C C   1 
ATOM 3313 O O   . CYS C 1 221 ? 154.269 129.003 152.310 1.00 101.63 ? 311 CYS C O   1 
ATOM 3314 C CB  . CYS C 1 221 ? 156.414 128.591 154.837 1.00 101.63 ? 311 CYS C CB  1 
ATOM 3315 S SG  . CYS C 1 221 ? 155.755 130.259 155.021 1.00 101.63 ? 311 CYS C SG  1 
ATOM 3316 N N   . THR C 1 222 ? 156.443 128.897 151.757 1.00 94.43  ? 312 THR C N   1 
ATOM 3317 C CA  . THR C 1 222 ? 156.218 129.664 150.543 1.00 94.43  ? 312 THR C CA  1 
ATOM 3318 C C   . THR C 1 222 ? 155.281 128.939 149.600 1.00 94.43  ? 312 THR C C   1 
ATOM 3319 O O   . THR C 1 222 ? 154.372 129.554 149.032 1.00 94.43  ? 312 THR C O   1 
ATOM 3320 C CB  . THR C 1 222 ? 157.540 129.950 149.851 1.00 94.43  ? 312 THR C CB  1 
ATOM 3321 O OG1 . THR C 1 222 ? 158.239 128.716 149.652 1.00 94.43  ? 312 THR C OG1 1 
ATOM 3322 C CG2 . THR C 1 222 ? 158.379 130.886 150.691 1.00 94.43  ? 312 THR C CG2 1 
ATOM 3323 N N   . ARG C 1 223 ? 155.504 127.643 149.404 1.00 88.72  ? 313 ARG C N   1 
ATOM 3324 C CA  . ARG C 1 223 ? 154.600 126.862 148.575 1.00 88.72  ? 313 ARG C CA  1 
ATOM 3325 C C   . ARG C 1 223 ? 153.165 127.086 149.010 1.00 88.72  ? 313 ARG C C   1 
ATOM 3326 O O   . ARG C 1 223 ? 152.327 127.536 148.223 1.00 88.72  ? 313 ARG C O   1 
ATOM 3327 C CB  . ARG C 1 223 ? 154.960 125.381 148.654 1.00 88.72  ? 313 ARG C CB  1 
ATOM 3328 C CG  . ARG C 1 223 ? 156.313 125.044 148.077 1.00 88.72  ? 313 ARG C CG  1 
ATOM 3329 C CD  . ARG C 1 223 ? 156.510 123.550 147.998 1.00 88.72  ? 313 ARG C CD  1 
ATOM 3330 N NE  . ARG C 1 223 ? 155.453 122.925 147.217 1.00 88.72  ? 313 ARG C NE  1 
ATOM 3331 C CZ  . ARG C 1 223 ? 155.568 121.744 146.627 1.00 88.72  ? 313 ARG C CZ  1 
ATOM 3332 N NH1 . ARG C 1 223 ? 156.697 121.060 146.726 1.00 88.72  ? 313 ARG C NH1 1 
ATOM 3333 N NH2 . ARG C 1 223 ? 154.554 121.249 145.938 1.00 88.72  ? 313 ARG C NH2 1 
ATOM 3334 N N   . TYR C 1 224 ? 152.876 126.800 150.275 1.00 81.28  ? 314 TYR C N   1 
ATOM 3335 C CA  . TYR C 1 224 ? 151.545 127.042 150.802 1.00 81.28  ? 314 TYR C CA  1 
ATOM 3336 C C   . TYR C 1 224 ? 151.068 128.441 150.465 1.00 81.28  ? 314 TYR C C   1 
ATOM 3337 O O   . TYR C 1 224 ? 150.056 128.608 149.779 1.00 81.28  ? 314 TYR C O   1 
ATOM 3338 C CB  . TYR C 1 224 ? 151.528 126.815 152.307 1.00 81.28  ? 314 TYR C CB  1 
ATOM 3339 C CG  . TYR C 1 224 ? 151.084 125.436 152.709 1.00 81.28  ? 314 TYR C CG  1 
ATOM 3340 C CD1 . TYR C 1 224 ? 150.178 124.733 151.937 1.00 81.28  ? 314 TYR C CD1 1 
ATOM 3341 C CD2 . TYR C 1 224 ? 151.560 124.846 153.860 1.00 81.28  ? 314 TYR C CD2 1 
ATOM 3342 C CE1 . TYR C 1 224 ? 149.756 123.493 152.301 1.00 81.28  ? 314 TYR C CE1 1 
ATOM 3343 C CE2 . TYR C 1 224 ? 151.148 123.605 154.230 1.00 81.28  ? 314 TYR C CE2 1 
ATOM 3344 C CZ  . TYR C 1 224 ? 150.249 122.931 153.444 1.00 81.28  ? 314 TYR C CZ  1 
ATOM 3345 O OH  . TYR C 1 224 ? 149.837 121.679 153.811 1.00 81.28  ? 314 TYR C OH  1 
ATOM 3346 N N   . LEU C 1 225 ? 151.799 129.457 150.916 1.00 79.79  ? 315 LEU C N   1 
ATOM 3347 C CA  . LEU C 1 225 ? 151.357 130.827 150.699 1.00 79.79  ? 315 LEU C CA  1 
ATOM 3348 C C   . LEU C 1 225 ? 150.990 131.055 149.248 1.00 79.79  ? 315 LEU C C   1 
ATOM 3349 O O   . LEU C 1 225 ? 150.063 131.811 148.940 1.00 79.79  ? 315 LEU C O   1 
ATOM 3350 C CB  . LEU C 1 225 ? 152.427 131.812 151.143 1.00 79.79  ? 315 LEU C CB  1 
ATOM 3351 C CG  . LEU C 1 225 ? 152.436 131.987 152.648 1.00 79.79  ? 315 LEU C CG  1 
ATOM 3352 C CD1 . LEU C 1 225 ? 153.593 132.861 153.073 1.00 79.79  ? 315 LEU C CD1 1 
ATOM 3353 C CD2 . LEU C 1 225 ? 151.126 132.617 153.037 1.00 79.79  ? 315 LEU C CD2 1 
ATOM 3354 N N   . LYS C 1 226 ? 151.687 130.389 148.338 1.00 78.97  ? 316 LYS C N   1 
ATOM 3355 C CA  . LYS C 1 226 ? 151.275 130.471 146.948 1.00 78.97  ? 316 LYS C CA  1 
ATOM 3356 C C   . LYS C 1 226 ? 149.963 129.739 146.740 1.00 78.97  ? 316 LYS C C   1 
ATOM 3357 O O   . LYS C 1 226 ? 149.083 130.214 146.014 1.00 78.97  ? 316 LYS C O   1 
ATOM 3358 C CB  . LYS C 1 226 ? 152.359 129.911 146.036 1.00 78.97  ? 316 LYS C CB  1 
ATOM 3359 C CG  . LYS C 1 226 ? 152.128 130.233 144.575 1.00 78.97  ? 316 LYS C CG  1 
ATOM 3360 C CD  . LYS C 1 226 ? 152.178 131.728 144.331 1.00 78.97  ? 316 LYS C CD  1 
ATOM 3361 C CE  . LYS C 1 226 ? 153.543 132.276 144.678 1.00 78.97  ? 316 LYS C CE  1 
ATOM 3362 N NZ  . LYS C 1 226 ? 154.605 131.634 143.859 1.00 78.97  ? 316 LYS C NZ  1 
ATOM 3363 N N   . GLY C 1 227 ? 149.800 128.593 147.396 1.00 68.83  ? 317 GLY C N   1 
ATOM 3364 C CA  . GLY C 1 227 ? 148.606 127.796 147.191 1.00 68.83  ? 317 GLY C CA  1 
ATOM 3365 C C   . GLY C 1 227 ? 147.337 128.511 147.596 1.00 68.83  ? 317 GLY C C   1 
ATOM 3366 O O   . GLY C 1 227 ? 146.256 128.192 147.100 1.00 68.83  ? 317 GLY C O   1 
ATOM 3367 N N   . TYR C 1 228 ? 147.444 129.483 148.487 1.00 60.92  ? 318 TYR C N   1 
ATOM 3368 C CA  . TYR C 1 228 ? 146.266 130.207 148.930 1.00 60.92  ? 318 TYR C CA  1 
ATOM 3369 C C   . TYR C 1 228 ? 146.176 131.595 148.335 1.00 60.92  ? 318 TYR C C   1 
ATOM 3370 O O   . TYR C 1 228 ? 145.368 132.398 148.807 1.00 60.92  ? 318 TYR C O   1 
ATOM 3371 C CB  . TYR C 1 228 ? 146.255 130.315 150.443 1.00 60.92  ? 318 TYR C CB  1 
ATOM 3372 C CG  . TYR C 1 228 ? 145.949 129.033 151.142 1.00 60.92  ? 318 TYR C CG  1 
ATOM 3373 C CD1 . TYR C 1 228 ? 144.933 128.967 152.058 1.00 60.92  ? 318 TYR C CD1 1 
ATOM 3374 C CD2 . TYR C 1 228 ? 146.676 127.894 150.894 1.00 60.92  ? 318 TYR C CD2 1 
ATOM 3375 C CE1 . TYR C 1 228 ? 144.649 127.812 152.709 1.00 60.92  ? 318 TYR C CE1 1 
ATOM 3376 C CE2 . TYR C 1 228 ? 146.396 126.734 151.537 1.00 60.92  ? 318 TYR C CE2 1 
ATOM 3377 C CZ  . TYR C 1 228 ? 145.377 126.698 152.446 1.00 60.92  ? 318 TYR C CZ  1 
ATOM 3378 O OH  . TYR C 1 228 ? 145.073 125.540 153.109 1.00 60.92  ? 318 TYR C OH  1 
ATOM 3379 N N   . GLY C 1 229 ? 146.999 131.905 147.342 1.00 72.25  ? 319 GLY C N   1 
ATOM 3380 C CA  . GLY C 1 229 ? 146.897 133.185 146.677 1.00 72.25  ? 319 GLY C CA  1 
ATOM 3381 C C   . GLY C 1 229 ? 147.036 134.397 147.565 1.00 72.25  ? 319 GLY C C   1 
ATOM 3382 O O   . GLY C 1 229 ? 146.478 135.444 147.245 1.00 72.25  ? 319 GLY C O   1 
ATOM 3383 N N   . VAL C 1 230 ? 147.752 134.293 148.677 1.00 70.70  ? 320 VAL C N   1 
ATOM 3384 C CA  . VAL C 1 230 ? 147.935 135.442 149.553 1.00 70.70  ? 320 VAL C CA  1 
ATOM 3385 C C   . VAL C 1 230 ? 149.395 135.870 149.512 1.00 70.70  ? 320 VAL C C   1 
ATOM 3386 O O   . VAL C 1 230 ? 150.301 135.047 149.673 1.00 70.70  ? 320 VAL C O   1 
ATOM 3387 C CB  . VAL C 1 230 ? 147.483 135.121 150.979 1.00 70.70  ? 320 VAL C CB  1 
ATOM 3388 C CG1 . VAL C 1 230 ? 146.007 134.825 150.976 1.00 70.70  ? 320 VAL C CG1 1 
ATOM 3389 C CG2 . VAL C 1 230 ? 148.238 133.935 151.503 1.00 70.70  ? 320 VAL C CG2 1 
ATOM 3390 N N   . SER C 1 231 ? 149.626 137.158 149.280 1.00 88.08  ? 321 SER C N   1 
ATOM 3391 C CA  . SER C 1 231 ? 150.978 137.642 149.038 1.00 88.08  ? 321 SER C CA  1 
ATOM 3392 C C   . SER C 1 231 ? 151.685 137.952 150.346 1.00 88.08  ? 321 SER C C   1 
ATOM 3393 O O   . SER C 1 231 ? 151.076 138.452 151.296 1.00 88.08  ? 321 SER C O   1 
ATOM 3394 C CB  . SER C 1 231 ? 150.954 138.879 148.154 1.00 88.08  ? 321 SER C CB  1 
ATOM 3395 O OG  . SER C 1 231 ? 152.262 139.403 148.031 1.00 88.08  ? 321 SER C OG  1 
ATOM 3396 N N   . TYR C 1 232 ? 152.979 137.674 150.377 1.00 95.22  ? 322 TYR C N   1 
ATOM 3397 C CA  . TYR C 1 232 ? 153.827 137.887 151.533 1.00 95.22  ? 322 TYR C CA  1 
ATOM 3398 C C   . TYR C 1 232 ? 155.065 138.652 151.105 1.00 95.22  ? 322 TYR C C   1 
ATOM 3399 O O   . TYR C 1 232 ? 155.246 138.972 149.929 1.00 95.22  ? 322 TYR C O   1 
ATOM 3400 C CB  . TYR C 1 232 ? 154.249 136.564 152.157 1.00 95.22  ? 322 TYR C CB  1 
ATOM 3401 C CG  . TYR C 1 232 ? 155.156 135.773 151.255 1.00 95.22  ? 322 TYR C CG  1 
ATOM 3402 C CD1 . TYR C 1 232 ? 154.668 135.171 150.111 1.00 95.22  ? 322 TYR C CD1 1 
ATOM 3403 C CD2 . TYR C 1 232 ? 156.498 135.631 151.542 1.00 95.22  ? 322 TYR C CD2 1 
ATOM 3404 C CE1 . TYR C 1 232 ? 155.487 134.452 149.282 1.00 95.22  ? 322 TYR C CE1 1 
ATOM 3405 C CE2 . TYR C 1 232 ? 157.325 134.908 150.722 1.00 95.22  ? 322 TYR C CE2 1 
ATOM 3406 C CZ  . TYR C 1 232 ? 156.812 134.319 149.592 1.00 95.22  ? 322 TYR C CZ  1 
ATOM 3407 O OH  . TYR C 1 232 ? 157.627 133.594 148.762 1.00 95.22  ? 322 TYR C OH  1 
ATOM 3408 N N   . ASP C 1 233 ? 155.929 138.929 152.072 1.00 120.70 ? 323 ASP C N   1 
ATOM 3409 C CA  . ASP C 1 233 ? 157.191 139.599 151.799 1.00 120.70 ? 323 ASP C CA  1 
ATOM 3410 C C   . ASP C 1 233 ? 158.329 138.594 151.884 1.00 120.70 ? 323 ASP C C   1 
ATOM 3411 O O   . ASP C 1 233 ? 158.344 137.734 152.767 1.00 120.70 ? 323 ASP C O   1 
ATOM 3412 C CB  . ASP C 1 233 ? 157.413 140.749 152.778 1.00 120.70 ? 323 ASP C CB  1 
ATOM 3413 C CG  . ASP C 1 233 ? 156.527 141.937 152.479 1.00 120.70 ? 323 ASP C CG  1 
ATOM 3414 O OD1 . ASP C 1 233 ? 155.743 141.861 151.511 1.00 120.70 ? 323 ASP C OD1 1 
ATOM 3415 O OD2 . ASP C 1 233 ? 156.614 142.946 153.206 1.00 120.70 ? 323 ASP C OD2 1 
ATOM 3416 N N   . GLU C 1 234 ? 159.282 138.713 150.964 1.00 128.15 ? 324 GLU C N   1 
ATOM 3417 C CA  . GLU C 1 234 ? 160.375 137.755 150.866 1.00 128.15 ? 324 GLU C CA  1 
ATOM 3418 C C   . GLU C 1 234 ? 161.349 137.847 152.026 1.00 128.15 ? 324 GLU C C   1 
ATOM 3419 O O   . GLU C 1 234 ? 162.136 136.916 152.227 1.00 128.15 ? 324 GLU C O   1 
ATOM 3420 C CB  . GLU C 1 234 ? 161.118 137.980 149.554 1.00 128.15 ? 324 GLU C CB  1 
ATOM 3421 C CG  . GLU C 1 234 ? 160.298 137.636 148.331 1.00 128.15 ? 324 GLU C CG  1 
ATOM 3422 C CD  . GLU C 1 234 ? 159.265 138.693 148.004 1.00 128.15 ? 324 GLU C CD  1 
ATOM 3423 O OE1 . GLU C 1 234 ? 159.196 139.708 148.729 1.00 128.15 ? 324 GLU C OE1 1 
ATOM 3424 O OE2 . GLU C 1 234 ? 158.520 138.506 147.022 1.00 128.15 ? 324 GLU C OE2 1 
ATOM 3425 N N   . ASN C 1 235 ? 161.314 138.934 152.788 1.00 133.83 ? 325 ASN C N   1 
ATOM 3426 C CA  . ASN C 1 235 ? 162.264 139.141 153.867 1.00 133.83 ? 325 ASN C CA  1 
ATOM 3427 C C   . ASN C 1 235 ? 161.650 138.935 155.241 1.00 133.83 ? 325 ASN C C   1 
ATOM 3428 O O   . ASN C 1 235 ? 162.331 138.435 156.144 1.00 133.83 ? 325 ASN C O   1 
ATOM 3429 C CB  . ASN C 1 235 ? 162.839 140.556 153.783 1.00 133.83 ? 325 ASN C CB  1 
ATOM 3430 C CG  . ASN C 1 235 ? 162.838 141.100 152.369 1.00 133.83 ? 325 ASN C CG  1 
ATOM 3431 O OD1 . ASN C 1 235 ? 162.778 140.345 151.402 1.00 133.83 ? 325 ASN C OD1 1 
ATOM 3432 N ND2 . ASN C 1 235 ? 162.895 142.417 152.243 1.00 133.83 ? 325 ASN C ND2 1 
ATOM 3433 N N   . ASP C 1 236 ? 160.380 139.288 155.414 1.00 123.46 ? 326 ASP C N   1 
ATOM 3434 C CA  . ASP C 1 236 ? 159.703 139.232 156.707 1.00 123.46 ? 326 ASP C CA  1 
ATOM 3435 C C   . ASP C 1 236 ? 159.173 137.818 156.882 1.00 123.46 ? 326 ASP C C   1 
ATOM 3436 O O   . ASP C 1 236 ? 158.015 137.526 156.581 1.00 123.46 ? 326 ASP C O   1 
ATOM 3437 C CB  . ASP C 1 236 ? 158.580 140.283 156.784 1.00 123.46 ? 326 ASP C CB  1 
ATOM 3438 C CG  . ASP C 1 236 ? 157.904 140.332 158.150 1.00 123.46 ? 326 ASP C CG  1 
ATOM 3439 O OD1 . ASP C 1 236 ? 157.636 139.268 158.754 1.00 123.46 ? 326 ASP C OD1 1 
ATOM 3440 O OD2 . ASP C 1 236 ? 157.632 141.453 158.624 1.00 123.46 ? 326 ASP C OD2 1 
ATOM 3441 N N   . GLN C 1 237 ? 160.034 136.933 157.375 1.00 120.76 ? 327 GLN C N   1 
ATOM 3442 C CA  . GLN C 1 237 ? 159.569 135.616 157.775 1.00 120.76 ? 327 GLN C CA  1 
ATOM 3443 C C   . GLN C 1 237 ? 158.553 135.704 158.898 1.00 120.76 ? 327 GLN C C   1 
ATOM 3444 O O   . GLN C 1 237 ? 157.662 134.855 158.986 1.00 120.76 ? 327 GLN C O   1 
ATOM 3445 C CB  . GLN C 1 237 ? 160.756 134.767 158.208 1.00 120.76 ? 327 GLN C CB  1 
ATOM 3446 C CG  . GLN C 1 237 ? 162.015 135.088 157.443 1.00 120.76 ? 327 GLN C CG  1 
ATOM 3447 C CD  . GLN C 1 237 ? 162.990 133.938 157.440 1.00 120.76 ? 327 GLN C CD  1 
ATOM 3448 O OE1 . GLN C 1 237 ? 163.143 133.238 158.439 1.00 120.76 ? 327 GLN C OE1 1 
ATOM 3449 N NE2 . GLN C 1 237 ? 163.656 133.732 156.310 1.00 120.76 ? 327 GLN C NE2 1 
ATOM 3450 N N   . SER C 1 238 ? 158.648 136.745 159.727 1.00 119.21 ? 328 SER C N   1 
ATOM 3451 C CA  . SER C 1 238 ? 157.917 136.799 160.987 1.00 119.21 ? 328 SER C CA  1 
ATOM 3452 C C   . SER C 1 238 ? 156.412 136.723 160.798 1.00 119.21 ? 328 SER C C   1 
ATOM 3453 O O   . SER C 1 238 ? 155.695 136.354 161.733 1.00 119.21 ? 328 SER C O   1 
ATOM 3454 C CB  . SER C 1 238 ? 158.263 138.084 161.729 1.00 119.21 ? 328 SER C CB  1 
ATOM 3455 O OG  . SER C 1 238 ? 157.417 139.136 161.301 1.00 119.21 ? 328 SER C OG  1 
ATOM 3456 N N   . LEU C 1 239 ? 155.905 137.085 159.626 1.00 111.58 ? 329 LEU C N   1 
ATOM 3457 C CA  . LEU C 1 239 ? 154.459 137.139 159.486 1.00 111.58 ? 329 LEU C CA  1 
ATOM 3458 C C   . LEU C 1 239 ? 153.920 135.969 158.677 1.00 111.58 ? 329 LEU C C   1 
ATOM 3459 O O   . LEU C 1 239 ? 152.699 135.790 158.591 1.00 111.58 ? 329 LEU C O   1 
ATOM 3460 C CB  . LEU C 1 239 ? 154.052 138.468 158.866 1.00 111.58 ? 329 LEU C CB  1 
ATOM 3461 C CG  . LEU C 1 239 ? 154.338 139.671 159.764 1.00 111.58 ? 329 LEU C CG  1 
ATOM 3462 C CD1 . LEU C 1 239 ? 153.429 140.827 159.391 1.00 111.58 ? 329 LEU C CD1 1 
ATOM 3463 C CD2 . LEU C 1 239 ? 154.172 139.314 161.236 1.00 111.58 ? 329 LEU C CD2 1 
ATOM 3464 N N   . TRP C 1 240 ? 154.806 135.175 158.076 1.00 105.68 ? 330 TRP C N   1 
ATOM 3465 C CA  . TRP C 1 240 ? 154.355 134.032 157.293 1.00 105.68 ? 330 TRP C CA  1 
ATOM 3466 C C   . TRP C 1 240 ? 153.428 133.148 158.106 1.00 105.68 ? 330 TRP C C   1 
ATOM 3467 O O   . TRP C 1 240 ? 152.294 132.881 157.699 1.00 105.68 ? 330 TRP C O   1 
ATOM 3468 C CB  . TRP C 1 240 ? 155.548 133.216 156.808 1.00 105.68 ? 330 TRP C CB  1 
ATOM 3469 C CG  . TRP C 1 240 ? 156.445 133.949 155.910 1.00 105.68 ? 330 TRP C CG  1 
ATOM 3470 C CD1 . TRP C 1 240 ? 156.143 135.047 155.176 1.00 105.68 ? 330 TRP C CD1 1 
ATOM 3471 C CD2 . TRP C 1 240 ? 157.811 133.644 155.641 1.00 105.68 ? 330 TRP C CD2 1 
ATOM 3472 N NE1 . TRP C 1 240 ? 157.239 135.454 154.464 1.00 105.68 ? 330 TRP C NE1 1 
ATOM 3473 C CE2 . TRP C 1 240 ? 158.279 134.605 154.730 1.00 105.68 ? 330 TRP C CE2 1 
ATOM 3474 C CE3 . TRP C 1 240 ? 158.687 132.653 156.082 1.00 105.68 ? 330 TRP C CE3 1 
ATOM 3475 C CZ2 . TRP C 1 240 ? 159.583 134.606 154.252 1.00 105.68 ? 330 TRP C CZ2 1 
ATOM 3476 C CZ3 . TRP C 1 240 ? 159.980 132.652 155.606 1.00 105.68 ? 330 TRP C CZ3 1 
ATOM 3477 C CH2 . TRP C 1 240 ? 160.417 133.622 154.701 1.00 105.68 ? 330 TRP C CH2 1 
ATOM 3478 N N   . LYS C 1 241 ? 153.909 132.666 159.246 1.00 103.66 ? 331 LYS C N   1 
ATOM 3479 C CA  . LYS C 1 241 ? 153.154 131.681 160.000 1.00 103.66 ? 331 LYS C CA  1 
ATOM 3480 C C   . LYS C 1 241 ? 151.807 132.234 160.417 1.00 103.66 ? 331 LYS C C   1 
ATOM 3481 O O   . LYS C 1 241 ? 150.772 131.578 160.244 1.00 103.66 ? 331 LYS C O   1 
ATOM 3482 C CB  . LYS C 1 241 ? 153.961 131.241 161.214 1.00 103.66 ? 331 LYS C CB  1 
ATOM 3483 C CG  . LYS C 1 241 ? 155.292 130.616 160.867 1.00 103.66 ? 331 LYS C CG  1 
ATOM 3484 C CD  . LYS C 1 241 ? 155.922 129.979 162.085 1.00 103.66 ? 331 LYS C CD  1 
ATOM 3485 C CE  . LYS C 1 241 ? 157.107 129.112 161.719 1.00 103.66 ? 331 LYS C CE  1 
ATOM 3486 N NZ  . LYS C 1 241 ? 157.487 128.210 162.844 1.00 103.66 ? 331 LYS C NZ  1 
ATOM 3487 N N   . ARG C 1 242 ? 151.793 133.444 160.955 1.00 94.16  ? 332 ARG C N   1 
ATOM 3488 C CA  . ARG C 1 242 ? 150.524 134.012 161.361 1.00 94.16  ? 332 ARG C CA  1 
ATOM 3489 C C   . ARG C 1 242 ? 149.585 134.165 160.184 1.00 94.16  ? 332 ARG C C   1 
ATOM 3490 O O   . ARG C 1 242 ? 148.398 133.838 160.302 1.00 94.16  ? 332 ARG C O   1 
ATOM 3491 C CB  . ARG C 1 242 ? 150.733 135.358 162.046 1.00 94.16  ? 332 ARG C CB  1 
ATOM 3492 C CG  . ARG C 1 242 ? 150.886 135.252 163.548 1.00 94.16  ? 332 ARG C CG  1 
ATOM 3493 C CD  . ARG C 1 242 ? 149.556 134.973 164.217 1.00 94.16  ? 332 ARG C CD  1 
ATOM 3494 N NE  . ARG C 1 242 ? 149.734 134.436 165.559 1.00 94.16  ? 332 ARG C NE  1 
ATOM 3495 C CZ  . ARG C 1 242 ? 148.771 134.363 166.470 1.00 94.16  ? 332 ARG C CZ  1 
ATOM 3496 N NH1 . ARG C 1 242 ? 147.553 134.795 166.190 1.00 94.16  ? 332 ARG C NH1 1 
ATOM 3497 N NH2 . ARG C 1 242 ? 149.031 133.855 167.665 1.00 94.16  ? 332 ARG C NH2 1 
ATOM 3498 N N   . GLN C 1 243 ? 150.081 134.630 159.043 1.00 79.75  ? 333 GLN C N   1 
ATOM 3499 C CA  . GLN C 1 243 ? 149.164 134.891 157.949 1.00 79.75  ? 333 GLN C CA  1 
ATOM 3500 C C   . GLN C 1 243 ? 148.656 133.588 157.358 1.00 79.75  ? 333 GLN C C   1 
ATOM 3501 O O   . GLN C 1 243 ? 147.499 133.494 156.938 1.00 79.75  ? 333 GLN C O   1 
ATOM 3502 C CB  . GLN C 1 243 ? 149.835 135.769 156.899 1.00 79.75  ? 333 GLN C CB  1 
ATOM 3503 C CG  . GLN C 1 243 ? 148.839 136.490 156.016 1.00 79.75  ? 333 GLN C CG  1 
ATOM 3504 C CD  . GLN C 1 243 ? 149.398 137.763 155.424 1.00 79.75  ? 333 GLN C CD  1 
ATOM 3505 O OE1 . GLN C 1 243 ? 150.550 138.118 155.661 1.00 79.75  ? 333 GLN C OE1 1 
ATOM 3506 N NE2 . GLN C 1 243 ? 148.577 138.468 154.656 1.00 79.75  ? 333 GLN C NE2 1 
ATOM 3507 N N   . LEU C 1 244 ? 149.484 132.550 157.372 1.00 73.23  ? 334 LEU C N   1 
ATOM 3508 C CA  . LEU C 1 244 ? 149.020 131.249 156.916 1.00 73.23  ? 334 LEU C CA  1 
ATOM 3509 C C   . LEU C 1 244 ? 147.936 130.719 157.832 1.00 73.23  ? 334 LEU C C   1 
ATOM 3510 O O   . LEU C 1 244 ? 146.910 130.204 157.369 1.00 73.23  ? 334 LEU C O   1 
ATOM 3511 C CB  . LEU C 1 244 ? 150.181 130.273 156.858 1.00 73.23  ? 334 LEU C CB  1 
ATOM 3512 C CG  . LEU C 1 244 ? 149.741 128.857 156.558 1.00 73.23  ? 334 LEU C CG  1 
ATOM 3513 C CD1 . LEU C 1 244 ? 149.053 128.861 155.235 1.00 73.23  ? 334 LEU C CD1 1 
ATOM 3514 C CD2 . LEU C 1 244 ? 150.946 127.969 156.512 1.00 73.23  ? 334 LEU C CD2 1 
ATOM 3515 N N   . ALA C 1 245 ? 148.154 130.827 159.138 1.00 72.81  ? 335 ALA C N   1 
ATOM 3516 C CA  . ALA C 1 245 ? 147.107 130.474 160.081 1.00 72.81  ? 335 ALA C CA  1 
ATOM 3517 C C   . ALA C 1 245 ? 145.818 131.193 159.733 1.00 72.81  ? 335 ALA C C   1 
ATOM 3518 O O   . ALA C 1 245 ? 144.782 130.561 159.502 1.00 72.81  ? 335 ALA C O   1 
ATOM 3519 C CB  . ALA C 1 245 ? 147.548 130.815 161.500 1.00 72.81  ? 335 ALA C CB  1 
ATOM 3520 N N   . LYS C 1 246 ? 145.879 132.520 159.644 1.00 71.21  ? 336 LYS C N   1 
ATOM 3521 C CA  . LYS C 1 246 ? 144.688 133.293 159.326 1.00 71.21  ? 336 LYS C CA  1 
ATOM 3522 C C   . LYS C 1 246 ? 144.117 132.926 157.971 1.00 71.21  ? 336 LYS C C   1 
ATOM 3523 O O   . LYS C 1 246 ? 142.951 133.223 157.698 1.00 71.21  ? 336 LYS C O   1 
ATOM 3524 C CB  . LYS C 1 246 ? 144.993 134.784 159.367 1.00 71.21  ? 336 LYS C CB  1 
ATOM 3525 C CG  . LYS C 1 246 ? 145.145 135.334 160.764 1.00 71.21  ? 336 LYS C CG  1 
ATOM 3526 C CD  . LYS C 1 246 ? 144.835 136.812 160.796 1.00 71.21  ? 336 LYS C CD  1 
ATOM 3527 C CE  . LYS C 1 246 ? 145.176 137.406 162.147 1.00 71.21  ? 336 LYS C CE  1 
ATOM 3528 N NZ  . LYS C 1 246 ? 144.543 138.738 162.338 1.00 71.21  ? 336 LYS C NZ  1 
ATOM 3529 N N   . ALA C 1 247 ? 144.908 132.298 157.114 1.00 62.43  ? 337 ALA C N   1 
ATOM 3530 C CA  . ALA C 1 247 ? 144.365 131.869 155.840 1.00 62.43  ? 337 ALA C CA  1 
ATOM 3531 C C   . ALA C 1 247 ? 143.570 130.583 155.984 1.00 62.43  ? 337 ALA C C   1 
ATOM 3532 O O   . ALA C 1 247 ? 142.466 130.474 155.449 1.00 62.43  ? 337 ALA C O   1 
ATOM 3533 C CB  . ALA C 1 247 ? 145.485 131.704 154.825 1.00 62.43  ? 337 ALA C CB  1 
ATOM 3534 N N   . VAL C 1 248 ? 144.108 129.585 156.683 1.00 67.41  ? 338 VAL C N   1 
ATOM 3535 C CA  . VAL C 1 248 ? 143.357 128.341 156.816 1.00 67.41  ? 338 VAL C CA  1 
ATOM 3536 C C   . VAL C 1 248 ? 142.230 128.447 157.821 1.00 67.41  ? 338 VAL C C   1 
ATOM 3537 O O   . VAL C 1 248 ? 141.186 127.814 157.625 1.00 67.41  ? 338 VAL C O   1 
ATOM 3538 C CB  . VAL C 1 248 ? 144.224 127.141 157.216 1.00 67.41  ? 338 VAL C CB  1 
ATOM 3539 C CG1 . VAL C 1 248 ? 145.160 126.791 156.097 1.00 67.41  ? 338 VAL C CG1 1 
ATOM 3540 C CG2 . VAL C 1 248 ? 144.977 127.439 158.494 1.00 67.41  ? 338 VAL C CG2 1 
ATOM 3541 N N   . GLY C 1 249 ? 142.402 129.214 158.880 1.00 71.80  ? 339 GLY C N   1 
ATOM 3542 C CA  . GLY C 1 249 ? 141.362 129.415 159.855 1.00 71.80  ? 339 GLY C CA  1 
ATOM 3543 C C   . GLY C 1 249 ? 141.733 129.182 161.297 1.00 71.80  ? 339 GLY C C   1 
ATOM 3544 O O   . GLY C 1 249 ? 140.845 129.232 162.154 1.00 71.80  ? 339 GLY C O   1 
ATOM 3545 N N   . LEU C 1 250 ? 143.005 128.971 161.601 1.00 86.36  ? 340 LEU C N   1 
ATOM 3546 C CA  . LEU C 1 250 ? 143.411 128.742 162.981 1.00 86.36  ? 340 LEU C CA  1 
ATOM 3547 C C   . LEU C 1 250 ? 143.196 130.045 163.731 1.00 86.36  ? 340 LEU C C   1 
ATOM 3548 O O   . LEU C 1 250 ? 144.013 130.961 163.684 1.00 86.36  ? 340 LEU C O   1 
ATOM 3549 C CB  . LEU C 1 250 ? 144.856 128.284 163.044 1.00 86.36  ? 340 LEU C CB  1 
ATOM 3550 C CG  . LEU C 1 250 ? 144.991 126.789 162.810 1.00 86.36  ? 340 LEU C CG  1 
ATOM 3551 C CD1 . LEU C 1 250 ? 146.410 126.350 163.060 1.00 86.36  ? 340 LEU C CD1 1 
ATOM 3552 C CD2 . LEU C 1 250 ? 144.042 126.053 163.713 1.00 86.36  ? 340 LEU C CD2 1 
ATOM 3553 N N   . THR C 1 251 ? 142.070 130.130 164.431 1.00 92.27  ? 341 THR C N   1 
ATOM 3554 C CA  . THR C 1 251 ? 141.581 131.413 164.909 1.00 92.27  ? 341 THR C CA  1 
ATOM 3555 C C   . THR C 1 251 ? 141.303 131.444 166.408 1.00 92.27  ? 341 THR C C   1 
ATOM 3556 O O   . THR C 1 251 ? 141.084 132.529 166.954 1.00 92.27  ? 341 THR C O   1 
ATOM 3557 C CB  . THR C 1 251 ? 140.307 131.784 164.136 1.00 92.27  ? 341 THR C CB  1 
ATOM 3558 O OG1 . THR C 1 251 ? 140.558 131.631 162.736 1.00 92.27  ? 341 THR C OG1 1 
ATOM 3559 C CG2 . THR C 1 251 ? 139.927 133.229 164.373 1.00 92.27  ? 341 THR C CG2 1 
ATOM 3560 N N   . ALA C 1 252 ? 141.324 130.306 167.095 1.00 110.50 ? 342 ALA C N   1 
ATOM 3561 C CA  . ALA C 1 252 ? 140.878 130.254 168.479 1.00 110.50 ? 342 ALA C CA  1 
ATOM 3562 C C   . ALA C 1 252 ? 141.743 131.131 169.378 1.00 110.50 ? 342 ALA C C   1 
ATOM 3563 O O   . ALA C 1 252 ? 142.805 131.623 168.992 1.00 110.50 ? 342 ALA C O   1 
ATOM 3564 C CB  . ALA C 1 252 ? 140.898 128.818 168.994 1.00 110.50 ? 342 ALA C CB  1 
ATOM 3565 N N   . ALA C 1 253 ? 141.258 131.325 170.605 1.00 115.50 ? 343 ALA C N   1 
ATOM 3566 C CA  . ALA C 1 253 ? 142.006 132.110 171.577 1.00 115.50 ? 343 ALA C CA  1 
ATOM 3567 C C   . ALA C 1 253 ? 143.387 131.523 171.819 1.00 115.50 ? 343 ALA C C   1 
ATOM 3568 O O   . ALA C 1 253 ? 144.382 132.260 171.862 1.00 115.50 ? 343 ALA C O   1 
ATOM 3569 C CB  . ALA C 1 253 ? 141.227 132.197 172.888 1.00 115.50 ? 343 ALA C CB  1 
ATOM 3570 N N   . TYR C 1 254 ? 143.475 130.203 171.978 1.00 118.19 ? 344 TYR C N   1 
ATOM 3571 C CA  . TYR C 1 254 ? 144.785 129.582 172.075 1.00 118.19 ? 344 TYR C CA  1 
ATOM 3572 C C   . TYR C 1 254 ? 145.575 129.804 170.796 1.00 118.19 ? 344 TYR C C   1 
ATOM 3573 O O   . TYR C 1 254 ? 146.799 129.967 170.830 1.00 118.19 ? 344 TYR C O   1 
ATOM 3574 C CB  . TYR C 1 254 ? 144.663 128.092 172.371 1.00 118.19 ? 344 TYR C CB  1 
ATOM 3575 C CG  . TYR C 1 254 ? 145.945 127.361 172.071 1.00 118.19 ? 344 TYR C CG  1 
ATOM 3576 C CD1 . TYR C 1 254 ? 146.058 126.540 170.960 1.00 118.19 ? 344 TYR C CD1 1 
ATOM 3577 C CD2 . TYR C 1 254 ? 147.059 127.528 172.878 1.00 118.19 ? 344 TYR C CD2 1 
ATOM 3578 C CE1 . TYR C 1 254 ? 147.238 125.885 170.678 1.00 118.19 ? 344 TYR C CE1 1 
ATOM 3579 C CE2 . TYR C 1 254 ? 148.242 126.878 172.603 1.00 118.19 ? 344 TYR C CE2 1 
ATOM 3580 C CZ  . TYR C 1 254 ? 148.326 126.058 171.503 1.00 118.19 ? 344 TYR C CZ  1 
ATOM 3581 O OH  . TYR C 1 254 ? 149.504 125.407 171.227 1.00 118.19 ? 344 TYR C OH  1 
ATOM 3582 N N   . ASP C 1 255 ? 144.885 129.816 169.654 1.00 110.34 ? 345 ASP C N   1 
ATOM 3583 C CA  . ASP C 1 255 ? 145.564 130.069 168.390 1.00 110.34 ? 345 ASP C CA  1 
ATOM 3584 C C   . ASP C 1 255 ? 146.199 131.451 168.383 1.00 110.34 ? 345 ASP C C   1 
ATOM 3585 O O   . ASP C 1 255 ? 147.194 131.684 167.689 1.00 110.34 ? 345 ASP C O   1 
ATOM 3586 C CB  . ASP C 1 255 ? 144.585 129.931 167.231 1.00 110.34 ? 345 ASP C CB  1 
ATOM 3587 C CG  . ASP C 1 255 ? 143.982 128.555 167.149 1.00 110.34 ? 345 ASP C CG  1 
ATOM 3588 O OD1 . ASP C 1 255 ? 144.613 127.600 167.645 1.00 110.34 ? 345 ASP C OD1 1 
ATOM 3589 O OD2 . ASP C 1 255 ? 142.881 128.428 166.575 1.00 110.34 ? 345 ASP C OD2 1 
ATOM 3590 N N   . ALA C 1 256 ? 145.633 132.383 169.147 1.00 117.72 ? 346 ALA C N   1 
ATOM 3591 C CA  . ALA C 1 256 ? 146.266 133.685 169.291 1.00 117.72 ? 346 ALA C CA  1 
ATOM 3592 C C   . ALA C 1 256 ? 147.386 133.664 170.318 1.00 117.72 ? 346 ALA C C   1 
ATOM 3593 O O   . ALA C 1 256 ? 148.443 134.254 170.074 1.00 117.72 ? 346 ALA C O   1 
ATOM 3594 C CB  . ALA C 1 256 ? 145.229 134.734 169.664 1.00 50.00  ? 346 ALA C CB  1 
ATOM 3595 N N   . SER C 1 257 ? 147.190 132.980 171.443 1.00 122.17 ? 347 SER C N   1 
ATOM 3596 C CA  . SER C 1 257 ? 148.165 133.026 172.524 1.00 122.17 ? 347 SER C CA  1 
ATOM 3597 C C   . SER C 1 257 ? 149.431 132.234 172.230 1.00 122.17 ? 347 SER C C   1 
ATOM 3598 O O   . SER C 1 257 ? 150.458 132.487 172.866 1.00 122.17 ? 347 SER C O   1 
ATOM 3599 C CB  . SER C 1 257 ? 147.537 132.508 173.816 1.00 122.17 ? 347 SER C CB  1 
ATOM 3600 O OG  . SER C 1 257 ? 146.823 131.310 173.581 1.00 122.17 ? 347 SER C OG  1 
ATOM 3601 N N   . TYR C 1 258 ? 149.389 131.293 171.297 1.00 128.12 ? 348 TYR C N   1 
ATOM 3602 C CA  . TYR C 1 258 ? 150.567 130.496 170.987 1.00 128.12 ? 348 TYR C CA  1 
ATOM 3603 C C   . TYR C 1 258 ? 151.599 131.360 170.278 1.00 128.12 ? 348 TYR C C   1 
ATOM 3604 O O   . TYR C 1 258 ? 151.244 132.286 169.543 1.00 128.12 ? 348 TYR C O   1 
ATOM 3605 C CB  . TYR C 1 258 ? 150.179 129.303 170.123 1.00 128.12 ? 348 TYR C CB  1 
ATOM 3606 C CG  . TYR C 1 258 ? 151.345 128.490 169.622 1.00 128.12 ? 348 TYR C CG  1 
ATOM 3607 C CD1 . TYR C 1 258 ? 151.960 128.789 168.414 1.00 128.12 ? 348 TYR C CD1 1 
ATOM 3608 C CD2 . TYR C 1 258 ? 151.828 127.418 170.353 1.00 128.12 ? 348 TYR C CD2 1 
ATOM 3609 C CE1 . TYR C 1 258 ? 153.012 128.043 167.950 1.00 128.12 ? 348 TYR C CE1 1 
ATOM 3610 C CE2 . TYR C 1 258 ? 152.887 126.669 169.899 1.00 128.12 ? 348 TYR C CE2 1 
ATOM 3611 C CZ  . TYR C 1 258 ? 153.477 126.987 168.698 1.00 128.12 ? 348 TYR C CZ  1 
ATOM 3612 O OH  . TYR C 1 258 ? 154.533 126.238 168.241 1.00 128.12 ? 348 TYR C OH  1 
ATOM 3613 N N   . THR C 1 259 ? 152.876 131.063 170.502 1.00 129.58 ? 349 THR C N   1 
ATOM 3614 C CA  . THR C 1 259 ? 153.964 131.804 169.869 1.00 129.58 ? 349 THR C CA  1 
ATOM 3615 C C   . THR C 1 259 ? 154.656 130.904 168.856 1.00 129.58 ? 349 THR C C   1 
ATOM 3616 O O   . THR C 1 259 ? 155.061 129.781 169.154 1.00 129.58 ? 349 THR C O   1 
ATOM 3617 C CB  . THR C 1 259 ? 154.936 132.336 170.914 1.00 129.58 ? 349 THR C CB  1 
ATOM 3618 O OG1 . THR C 1 259 ? 156.009 133.024 170.260 1.00 129.58 ? 349 THR C OG1 1 
ATOM 3619 C CG2 . THR C 1 259 ? 155.490 131.211 171.781 1.00 129.58 ? 349 THR C CG2 1 
ATOM 3620 N N   . PHE C 1 260 ? 154.786 131.407 167.633 1.00 122.99 ? 350 PHE C N   1 
ATOM 3621 C CA  . PHE C 1 260 ? 155.460 130.658 166.585 1.00 122.99 ? 350 PHE C CA  1 
ATOM 3622 C C   . PHE C 1 260 ? 156.948 130.537 166.882 1.00 122.99 ? 350 PHE C C   1 
ATOM 3623 O O   . PHE C 1 260 ? 157.536 131.386 167.555 1.00 122.99 ? 350 PHE C O   1 
ATOM 3624 C CB  . PHE C 1 260 ? 155.256 131.341 165.236 1.00 122.99 ? 350 PHE C CB  1 
ATOM 3625 C CG  . PHE C 1 260 ? 153.891 131.135 164.653 1.00 122.99 ? 350 PHE C CG  1 
ATOM 3626 C CD1 . PHE C 1 260 ? 153.411 129.862 164.412 1.00 122.99 ? 350 PHE C CD1 1 
ATOM 3627 C CD2 . PHE C 1 260 ? 153.086 132.218 164.345 1.00 122.99 ? 350 PHE C CD2 1 
ATOM 3628 C CE1 . PHE C 1 260 ? 152.158 129.674 163.873 1.00 122.99 ? 350 PHE C CE1 1 
ATOM 3629 C CE2 . PHE C 1 260 ? 151.833 132.030 163.808 1.00 122.99 ? 350 PHE C CE2 1 
ATOM 3630 C CZ  . PHE C 1 260 ? 151.369 130.763 163.570 1.00 122.99 ? 350 PHE C CZ  1 
ATOM 3631 N N   . SER C 1 261 ? 157.552 129.471 166.378 1.00 123.84 ? 351 SER C N   1 
ATOM 3632 C CA  . SER C 1 261 ? 158.983 129.294 166.537 1.00 123.84 ? 351 SER C CA  1 
ATOM 3633 C C   . SER C 1 261 ? 159.710 129.810 165.301 1.00 123.84 ? 351 SER C C   1 
ATOM 3634 O O   . SER C 1 261 ? 159.115 129.899 164.221 1.00 123.84 ? 351 SER C O   1 
ATOM 3635 C CB  . SER C 1 261 ? 159.317 127.822 166.763 1.00 123.84 ? 351 SER C CB  1 
ATOM 3636 O OG  . SER C 1 261 ? 158.641 127.000 165.830 1.00 123.84 ? 351 SER C OG  1 
ATOM 3637 N N   . PRO C 1 262 ? 160.986 130.173 165.417 1.00 126.05 ? 352 PRO C N   1 
ATOM 3638 C CA  . PRO C 1 262 ? 161.751 130.578 164.236 1.00 126.05 ? 352 PRO C CA  1 
ATOM 3639 C C   . PRO C 1 262 ? 162.236 129.369 163.452 1.00 126.05 ? 352 PRO C C   1 
ATOM 3640 O O   . PRO C 1 262 ? 162.218 128.230 163.922 1.00 126.05 ? 352 PRO C O   1 
ATOM 3641 C CB  . PRO C 1 262 ? 162.919 131.367 164.826 1.00 126.05 ? 352 PRO C CB  1 
ATOM 3642 C CG  . PRO C 1 262 ? 163.125 130.744 166.162 1.00 126.05 ? 352 PRO C CG  1 
ATOM 3643 C CD  . PRO C 1 262 ? 161.759 130.347 166.660 1.00 126.05 ? 352 PRO C CD  1 
ATOM 3644 N N   . PHE C 1 263 ? 162.686 129.632 162.230 1.00 131.52 ? 353 PHE C N   1 
ATOM 3645 C CA  . PHE C 1 263 ? 163.168 128.564 161.372 1.00 131.52 ? 353 PHE C CA  1 
ATOM 3646 C C   . PHE C 1 263 ? 164.577 128.140 161.766 1.00 131.52 ? 353 PHE C C   1 
ATOM 3647 O O   . PHE C 1 263 ? 165.214 128.726 162.644 1.00 131.52 ? 353 PHE C O   1 
ATOM 3648 C CB  . PHE C 1 263 ? 163.154 128.997 159.912 1.00 131.52 ? 353 PHE C CB  1 
ATOM 3649 C CG  . PHE C 1 263 ? 161.784 129.138 159.348 1.00 131.52 ? 353 PHE C CG  1 
ATOM 3650 C CD1 . PHE C 1 263 ? 160.901 128.076 159.386 1.00 131.52 ? 353 PHE C CD1 1 
ATOM 3651 C CD2 . PHE C 1 263 ? 161.373 130.331 158.786 1.00 131.52 ? 353 PHE C CD2 1 
ATOM 3652 C CE1 . PHE C 1 263 ? 159.634 128.200 158.872 1.00 131.52 ? 353 PHE C CE1 1 
ATOM 3653 C CE2 . PHE C 1 263 ? 160.107 130.460 158.270 1.00 131.52 ? 353 PHE C CE2 1 
ATOM 3654 C CZ  . PHE C 1 263 ? 159.236 129.394 158.312 1.00 131.52 ? 353 PHE C CZ  1 
ATOM 3655 N N   . SER C 1 264 ? 165.062 127.103 161.093 1.00 145.47 ? 354 SER C N   1 
ATOM 3656 C CA  . SER C 1 264 ? 166.398 126.577 161.341 1.00 145.47 ? 354 SER C CA  1 
ATOM 3657 C C   . SER C 1 264 ? 167.465 127.446 160.686 1.00 145.47 ? 354 SER C C   1 
ATOM 3658 O O   . SER C 1 264 ? 168.483 126.940 160.213 1.00 145.47 ? 354 SER C O   1 
ATOM 3659 C CB  . SER C 1 264 ? 166.509 125.139 160.831 1.00 145.47 ? 354 SER C CB  1 
ATOM 3660 O OG  . SER C 1 264 ? 166.900 125.114 159.469 1.00 145.47 ? 354 SER C OG  1 
ATOM 3661 N N   . MET D 1 118 ? 132.956 134.720 70.027  1.00 190.88 ? 208 MET D N   1 
ATOM 3662 C CA  . MET D 1 118 ? 133.519 133.517 70.630  1.00 190.88 ? 208 MET D CA  1 
ATOM 3663 C C   . MET D 1 118 ? 134.762 133.849 71.446  1.00 190.88 ? 208 MET D C   1 
ATOM 3664 O O   . MET D 1 118 ? 135.028 133.225 72.482  1.00 190.88 ? 208 MET D O   1 
ATOM 3665 C CB  . MET D 1 118 ? 133.854 132.482 69.555  1.00 50.00  ? 208 MET D CB  1 
ATOM 3666 C CG  . MET D 1 118 ? 132.640 131.922 68.831  1.00 50.00  ? 208 MET D CG  1 
ATOM 3667 S SD  . MET D 1 118 ? 131.488 131.095 69.943  1.00 50.00  ? 208 MET D SD  1 
ATOM 3668 C CE  . MET D 1 118 ? 132.464 129.683 70.454  1.00 50.00  ? 208 MET D CE  1 
ATOM 3669 N N   . GLY D 1 119 ? 135.532 134.848 71.000  1.00 193.24 ? 209 GLY D N   1 
ATOM 3670 C CA  . GLY D 1 119 ? 136.587 135.392 71.848  1.00 193.24 ? 209 GLY D CA  1 
ATOM 3671 C C   . GLY D 1 119 ? 136.028 135.758 73.211  1.00 193.24 ? 209 GLY D C   1 
ATOM 3672 O O   . GLY D 1 119 ? 136.421 135.185 74.238  1.00 193.24 ? 209 GLY D O   1 
ATOM 3673 N N   . GLU D 1 120 ? 135.075 136.691 73.226  1.00 188.49 ? 210 GLU D N   1 
ATOM 3674 C CA  . GLU D 1 120 ? 134.464 137.130 74.470  1.00 188.49 ? 210 GLU D CA  1 
ATOM 3675 C C   . GLU D 1 120 ? 133.967 135.953 75.290  1.00 188.49 ? 210 GLU D C   1 
ATOM 3676 O O   . GLU D 1 120 ? 134.102 135.953 76.516  1.00 188.49 ? 210 GLU D O   1 
ATOM 3677 C CB  . GLU D 1 120 ? 133.312 138.096 74.186  1.00 50.00  ? 210 GLU D CB  1 
ATOM 3678 C CG  . GLU D 1 120 ? 133.747 139.424 73.588  1.00 50.00  ? 210 GLU D CG  1 
ATOM 3679 C CD  . GLU D 1 120 ? 132.572 140.324 73.254  1.00 50.00  ? 210 GLU D CD  1 
ATOM 3680 O OE1 . GLU D 1 120 ? 131.421 139.845 73.310  1.00 50.00  ? 210 GLU D OE1 1 
ATOM 3681 O OE2 . GLU D 1 120 ? 132.802 141.509 72.934  1.00 50.00  ? 210 GLU D OE2 1 
ATOM 3682 N N   . TRP D 1 121 ? 133.388 134.951 74.630  1.00 179.80 ? 211 TRP D N   1 
ATOM 3683 C CA  . TRP D 1 121 ? 133.024 133.721 75.320  1.00 179.80 ? 211 TRP D CA  1 
ATOM 3684 C C   . TRP D 1 121 ? 134.219 133.150 76.066  1.00 179.80 ? 211 TRP D C   1 
ATOM 3685 O O   . TRP D 1 121 ? 134.112 132.782 77.240  1.00 179.80 ? 211 TRP D O   1 
ATOM 3686 C CB  . TRP D 1 121 ? 132.477 132.689 74.331  1.00 50.00  ? 211 TRP D CB  1 
ATOM 3687 C CG  . TRP D 1 121 ? 131.141 133.055 73.761  1.00 50.00  ? 211 TRP D CG  1 
ATOM 3688 C CD1 . TRP D 1 121 ? 130.898 133.699 72.582  1.00 50.00  ? 211 TRP D CD1 1 
ATOM 3689 C CD2 . TRP D 1 121 ? 129.859 132.799 74.347  1.00 50.00  ? 211 TRP D CD2 1 
ATOM 3690 N NE1 . TRP D 1 121 ? 129.546 133.860 72.399  1.00 50.00  ? 211 TRP D NE1 1 
ATOM 3691 C CE2 . TRP D 1 121 ? 128.885 133.315 73.468  1.00 50.00  ? 211 TRP D CE2 1 
ATOM 3692 C CE3 . TRP D 1 121 ? 129.431 132.185 75.530  1.00 50.00  ? 211 TRP D CE3 1 
ATOM 3693 C CZ2 . TRP D 1 121 ? 127.519 133.235 73.733  1.00 50.00  ? 211 TRP D CZ2 1 
ATOM 3694 C CZ3 . TRP D 1 121 ? 128.076 132.107 75.789  1.00 50.00  ? 211 TRP D CZ3 1 
ATOM 3695 C CH2 . TRP D 1 121 ? 127.136 132.629 74.896  1.00 50.00  ? 211 TRP D CH2 1 
ATOM 3696 N N   . LYS D 1 122 ? 135.368 133.081 75.401  1.00 178.07 ? 212 LYS D N   1 
ATOM 3697 C CA  . LYS D 1 122 ? 136.553 132.514 76.031  1.00 178.07 ? 212 LYS D CA  1 
ATOM 3698 C C   . LYS D 1 122 ? 137.040 133.343 77.210  1.00 178.07 ? 212 LYS D C   1 
ATOM 3699 O O   . LYS D 1 122 ? 137.301 132.782 78.283  1.00 178.07 ? 212 LYS D O   1 
ATOM 3700 C CB  . LYS D 1 122 ? 137.676 132.369 75.003  1.00 50.00  ? 212 LYS D CB  1 
ATOM 3701 C CG  . LYS D 1 122 ? 137.391 131.351 73.910  1.00 50.00  ? 212 LYS D CG  1 
ATOM 3702 C CD  . LYS D 1 122 ? 138.535 131.275 72.913  1.00 50.00  ? 212 LYS D CD  1 
ATOM 3703 C CE  . LYS D 1 122 ? 138.260 130.241 71.834  1.00 50.00  ? 212 LYS D CE  1 
ATOM 3704 N NZ  . LYS D 1 122 ? 139.362 130.174 70.835  1.00 50.00  ? 212 LYS D NZ  1 
ATOM 3705 N N   . LYS D 1 123 ? 137.175 134.656 77.034  1.00 175.62 ? 213 LYS D N   1 
ATOM 3706 C CA  . LYS D 1 123 ? 137.623 135.461 78.167  1.00 175.62 ? 213 LYS D CA  1 
ATOM 3707 C C   . LYS D 1 123 ? 136.613 135.405 79.303  1.00 175.62 ? 213 LYS D C   1 
ATOM 3708 O O   . LYS D 1 123 ? 136.989 135.457 80.482  1.00 175.62 ? 213 LYS D O   1 
ATOM 3709 C CB  . LYS D 1 123 ? 137.855 136.911 77.738  1.00 50.00  ? 213 LYS D CB  1 
ATOM 3710 C CG  . LYS D 1 123 ? 139.019 137.096 76.777  1.00 50.00  ? 213 LYS D CG  1 
ATOM 3711 C CD  . LYS D 1 123 ? 139.177 138.552 76.374  1.00 50.00  ? 213 LYS D CD  1 
ATOM 3712 C CE  . LYS D 1 123 ? 140.355 138.741 75.433  1.00 50.00  ? 213 LYS D CE  1 
ATOM 3713 N NZ  . LYS D 1 123 ? 140.507 140.161 75.011  1.00 50.00  ? 213 LYS D NZ  1 
ATOM 3714 N N   . ALA D 1 124 ? 135.340 135.339 78.925  1.00 173.31 ? 214 ALA D N   1 
ATOM 3715 C CA  . ALA D 1 124 ? 134.288 135.268 79.906  1.00 173.31 ? 214 ALA D CA  1 
ATOM 3716 C C   . ALA D 1 124 ? 134.439 133.991 80.645  1.00 173.31 ? 214 ALA D C   1 
ATOM 3717 O O   . ALA D 1 124 ? 134.277 133.920 81.879  1.00 173.31 ? 214 ALA D O   1 
ATOM 3718 C CB  . ALA D 1 124 ? 132.918 135.373 79.254  1.00 50.00  ? 214 ALA D CB  1 
ATOM 3719 N N   . ARG D 1 125 ? 134.700 132.923 79.900  1.00 157.23 ? 215 ARG D N   1 
ATOM 3720 C CA  . ARG D 1 125 ? 134.877 131.625 80.520  1.00 157.23 ? 215 ARG D CA  1 
ATOM 3721 C C   . ARG D 1 125 ? 135.951 131.714 81.560  1.00 157.23 ? 215 ARG D C   1 
ATOM 3722 O O   . ARG D 1 125 ? 135.791 131.232 82.680  1.00 157.23 ? 215 ARG D O   1 
ATOM 3723 C CB  . ARG D 1 125 ? 135.323 130.591 79.496  1.00 50.00  ? 215 ARG D CB  1 
ATOM 3724 C CG  . ARG D 1 125 ? 134.255 130.084 78.552  1.00 50.00  ? 215 ARG D CG  1 
ATOM 3725 C CD  . ARG D 1 125 ? 134.832 129.012 77.641  1.00 50.00  ? 215 ARG D CD  1 
ATOM 3726 N NE  . ARG D 1 125 ? 135.215 127.810 78.378  1.00 50.00  ? 215 ARG D NE  1 
ATOM 3727 C CZ  . ARG D 1 125 ? 136.452 127.539 78.783  1.00 50.00  ? 215 ARG D CZ  1 
ATOM 3728 N NH1 . ARG D 1 125 ? 136.703 126.421 79.450  1.00 50.00  ? 215 ARG D NH1 1 
ATOM 3729 N NH2 . ARG D 1 125 ? 137.442 128.379 78.515  1.00 50.00  ? 215 ARG D NH2 1 
ATOM 3730 N N   . GLU D 1 126 ? 137.063 132.330 81.193  1.00 151.95 ? 216 GLU D N   1 
ATOM 3731 C CA  . GLU D 1 126 ? 138.185 132.362 82.112  1.00 151.95 ? 216 GLU D CA  1 
ATOM 3732 C C   . GLU D 1 126 ? 137.828 133.098 83.387  1.00 151.95 ? 216 GLU D C   1 
ATOM 3733 O O   . GLU D 1 126 ? 138.134 132.635 84.484  1.00 151.95 ? 216 GLU D O   1 
ATOM 3734 C CB  . GLU D 1 126 ? 139.400 133.015 81.450  1.00 50.00  ? 216 GLU D CB  1 
ATOM 3735 C CG  . GLU D 1 126 ? 139.989 132.211 80.301  1.00 50.00  ? 216 GLU D CG  1 
ATOM 3736 C CD  . GLU D 1 126 ? 141.145 132.924 79.625  1.00 50.00  ? 216 GLU D CD  1 
ATOM 3737 O OE1 . GLU D 1 126 ? 141.365 134.116 79.923  1.00 50.00  ? 216 GLU D OE1 1 
ATOM 3738 O OE2 . GLU D 1 126 ? 141.831 132.293 78.794  1.00 50.00  ? 216 GLU D OE2 1 
ATOM 3739 N N   . GLU D 1 127 ? 137.117 134.207 83.250  1.00 155.02 ? 217 GLU D N   1 
ATOM 3740 C CA  . GLU D 1 127 ? 136.790 135.002 84.410  1.00 155.02 ? 217 GLU D CA  1 
ATOM 3741 C C   . GLU D 1 127 ? 135.950 134.157 85.295  1.00 155.02 ? 217 GLU D C   1 
ATOM 3742 O O   . GLU D 1 127 ? 136.112 134.139 86.507  1.00 155.02 ? 217 GLU D O   1 
ATOM 3743 C CB  . GLU D 1 127 ? 136.062 136.291 84.021  1.00 50.00  ? 217 GLU D CB  1 
ATOM 3744 C CG  . GLU D 1 127 ? 136.932 137.297 83.283  1.00 50.00  ? 217 GLU D CG  1 
ATOM 3745 C CD  . GLU D 1 127 ? 136.157 138.528 82.852  1.00 50.00  ? 217 GLU D CD  1 
ATOM 3746 O OE1 . GLU D 1 127 ? 134.914 138.517 82.958  1.00 50.00  ? 217 GLU D OE1 1 
ATOM 3747 O OE2 . GLU D 1 127 ? 136.794 139.505 82.405  1.00 50.00  ? 217 GLU D OE2 1 
ATOM 3748 N N   . ASP D 1 128 ? 135.044 133.411 84.673  1.00 143.29 ? 218 ASP D N   1 
ATOM 3749 C CA  . ASP D 1 128 ? 134.228 132.496 85.437  1.00 143.29 ? 218 ASP D CA  1 
ATOM 3750 C C   . ASP D 1 128 ? 135.158 131.644 86.264  1.00 143.29 ? 218 ASP D C   1 
ATOM 3751 O O   . ASP D 1 128 ? 134.969 131.520 87.470  1.00 143.29 ? 218 ASP D O   1 
ATOM 3752 C CB  . ASP D 1 128 ? 133.384 131.617 84.521  1.00 50.00  ? 218 ASP D CB  1 
ATOM 3753 C CG  . ASP D 1 128 ? 132.474 132.421 83.622  1.00 50.00  ? 218 ASP D CG  1 
ATOM 3754 O OD1 . ASP D 1 128 ? 132.215 133.601 83.939  1.00 50.00  ? 218 ASP D OD1 1 
ATOM 3755 O OD2 . ASP D 1 128 ? 132.019 131.876 82.595  1.00 50.00  ? 218 ASP D OD2 1 
ATOM 3756 N N   . LYS D 1 129 ? 136.176 131.058 85.637  1.00 143.56 ? 219 LYS D N   1 
ATOM 3757 C CA  . LYS D 1 129 ? 137.013 130.174 86.425  1.00 143.56 ? 219 LYS D CA  1 
ATOM 3758 C C   . LYS D 1 129 ? 137.695 130.899 87.566  1.00 143.56 ? 219 LYS D C   1 
ATOM 3759 O O   . LYS D 1 129 ? 137.736 130.372 88.681  1.00 143.56 ? 219 LYS D O   1 
ATOM 3760 C CB  . LYS D 1 129 ? 138.062 129.507 85.534  1.00 50.00  ? 219 LYS D CB  1 
ATOM 3761 C CG  . LYS D 1 129 ? 137.485 128.544 84.508  1.00 50.00  ? 219 LYS D CG  1 
ATOM 3762 C CD  . LYS D 1 129 ? 138.576 127.937 83.644  1.00 50.00  ? 219 LYS D CD  1 
ATOM 3763 C CE  . LYS D 1 129 ? 138.002 126.957 82.634  1.00 50.00  ? 219 LYS D CE  1 
ATOM 3764 N NZ  . LYS D 1 129 ? 139.059 126.372 81.764  1.00 50.00  ? 219 LYS D NZ  1 
ATOM 3765 N N   . GLU D 1 130 ? 138.226 132.094 87.318  1.00 148.48 ? 220 GLU D N   1 
ATOM 3766 C CA  . GLU D 1 130 ? 138.790 132.850 88.429  1.00 148.48 ? 220 GLU D CA  1 
ATOM 3767 C C   . GLU D 1 130 ? 137.734 133.092 89.497  1.00 148.48 ? 220 GLU D C   1 
ATOM 3768 O O   . GLU D 1 130 ? 137.994 132.923 90.694  1.00 148.48 ? 220 GLU D O   1 
ATOM 3769 C CB  . GLU D 1 130 ? 139.401 134.170 87.955  1.00 148.48 ? 220 GLU D CB  1 
ATOM 3770 C CG  . GLU D 1 130 ? 140.781 134.021 87.316  1.00 148.48 ? 220 GLU D CG  1 
ATOM 3771 C CD  . GLU D 1 130 ? 140.740 133.894 85.812  1.00 148.48 ? 220 GLU D CD  1 
ATOM 3772 O OE1 . GLU D 1 130 ? 139.822 134.463 85.203  1.00 148.48 ? 220 GLU D OE1 1 
ATOM 3773 O OE2 . GLU D 1 130 ? 141.626 133.228 85.239  1.00 148.48 ? 220 GLU D OE2 1 
ATOM 3774 N N   . TRP D 1 131 ? 136.527 133.462 89.075  1.00 131.37 ? 221 TRP D N   1 
ATOM 3775 C CA  . TRP D 1 131 ? 135.424 133.594 90.012  1.00 131.37 ? 221 TRP D CA  1 
ATOM 3776 C C   . TRP D 1 131 ? 135.227 132.315 90.802  1.00 131.37 ? 221 TRP D C   1 
ATOM 3777 O O   . TRP D 1 131 ? 134.957 132.353 92.011  1.00 131.37 ? 221 TRP D O   1 
ATOM 3778 C CB  . TRP D 1 131 ? 134.152 133.955 89.254  1.00 131.37 ? 221 TRP D CB  1 
ATOM 3779 C CG  . TRP D 1 131 ? 132.957 133.926 90.104  1.00 131.37 ? 221 TRP D CG  1 
ATOM 3780 C CD1 . TRP D 1 131 ? 132.667 134.766 91.129  1.00 131.37 ? 221 TRP D CD1 1 
ATOM 3781 C CD2 . TRP D 1 131 ? 131.884 132.994 90.029  1.00 131.37 ? 221 TRP D CD2 1 
ATOM 3782 N NE1 . TRP D 1 131 ? 131.468 134.423 91.692  1.00 131.37 ? 221 TRP D NE1 1 
ATOM 3783 C CE2 . TRP D 1 131 ? 130.967 133.333 91.033  1.00 131.37 ? 221 TRP D CE2 1 
ATOM 3784 C CE3 . TRP D 1 131 ? 131.607 131.904 89.205  1.00 131.37 ? 221 TRP D CE3 1 
ATOM 3785 C CZ2 . TRP D 1 131 ? 129.797 132.622 91.239  1.00 131.37 ? 221 TRP D CZ2 1 
ATOM 3786 C CZ3 . TRP D 1 131 ? 130.441 131.205 89.408  1.00 131.37 ? 221 TRP D CZ3 1 
ATOM 3787 C CH2 . TRP D 1 131 ? 129.549 131.567 90.414  1.00 131.37 ? 221 TRP D CH2 1 
ATOM 3788 N N   . ARG D 1 132 ? 135.378 131.178 90.133  1.00 128.74 ? 222 ARG D N   1 
ATOM 3789 C CA  . ARG D 1 132 ? 135.299 129.899 90.815  1.00 128.74 ? 222 ARG D CA  1 
ATOM 3790 C C   . ARG D 1 132 ? 136.340 129.821 91.916  1.00 128.74 ? 222 ARG D C   1 
ATOM 3791 O O   . ARG D 1 132 ? 136.074 129.302 92.999  1.00 128.74 ? 222 ARG D O   1 
ATOM 3792 C CB  . ARG D 1 132 ? 135.495 128.749 89.831  1.00 128.74 ? 222 ARG D CB  1 
ATOM 3793 C CG  . ARG D 1 132 ? 134.585 128.749 88.634  1.00 128.74 ? 222 ARG D CG  1 
ATOM 3794 C CD  . ARG D 1 132 ? 134.667 127.401 87.948  1.00 128.74 ? 222 ARG D CD  1 
ATOM 3795 N NE  . ARG D 1 132 ? 134.605 127.498 86.497  1.00 128.74 ? 222 ARG D NE  1 
ATOM 3796 C CZ  . ARG D 1 132 ? 133.476 127.464 85.805  1.00 128.74 ? 222 ARG D CZ  1 
ATOM 3797 N NH1 . ARG D 1 132 ? 132.320 127.357 86.438  1.00 128.74 ? 222 ARG D NH1 1 
ATOM 3798 N NH2 . ARG D 1 132 ? 133.503 127.553 84.485  1.00 128.74 ? 222 ARG D NH2 1 
ATOM 3799 N N   . LYS D 1 133 ? 137.544 130.322 91.649  1.00 127.54 ? 223 LYS D N   1 
ATOM 3800 C CA  . LYS D 1 133 ? 138.610 130.206 92.635  1.00 127.54 ? 223 LYS D CA  1 
ATOM 3801 C C   . LYS D 1 133 ? 138.286 131.007 93.886  1.00 127.54 ? 223 LYS D C   1 
ATOM 3802 O O   . LYS D 1 133 ? 138.469 130.527 95.012  1.00 127.54 ? 223 LYS D O   1 
ATOM 3803 C CB  . LYS D 1 133 ? 139.939 130.647 92.022  1.00 127.54 ? 223 LYS D CB  1 
ATOM 3804 C CG  . LYS D 1 133 ? 140.786 129.478 91.524  1.00 127.54 ? 223 LYS D CG  1 
ATOM 3805 C CD  . LYS D 1 133 ? 142.220 129.887 91.228  1.00 127.54 ? 223 LYS D CD  1 
ATOM 3806 C CE  . LYS D 1 133 ? 143.015 128.718 90.664  1.00 127.54 ? 223 LYS D CE  1 
ATOM 3807 N NZ  . LYS D 1 133 ? 142.378 128.129 89.460  1.00 127.54 ? 223 LYS D NZ  1 
ATOM 3808 N N   . SER D 1 134 ? 137.822 132.244 93.706  1.00 121.61 ? 224 SER D N   1 
ATOM 3809 C CA  . SER D 1 134 ? 137.358 133.026 94.841  1.00 121.61 ? 224 SER D CA  1 
ATOM 3810 C C   . SER D 1 134 ? 136.286 132.285 95.614  1.00 121.61 ? 224 SER D C   1 
ATOM 3811 O O   . SER D 1 134 ? 136.359 132.185 96.849  1.00 121.61 ? 224 SER D O   1 
ATOM 3812 C CB  . SER D 1 134 ? 136.807 134.371 94.366  1.00 121.61 ? 224 SER D CB  1 
ATOM 3813 O OG  . SER D 1 134 ? 135.426 134.269 94.065  1.00 121.61 ? 224 SER D OG  1 
ATOM 3814 N N   . THR D 1 135 ? 135.289 131.775 94.901  1.00 116.28 ? 225 THR D N   1 
ATOM 3815 C CA  . THR D 1 135 ? 134.250 130.999 95.554  1.00 116.28 ? 225 THR D CA  1 
ATOM 3816 C C   . THR D 1 135 ? 134.859 129.867 96.362  1.00 116.28 ? 225 THR D C   1 
ATOM 3817 O O   . THR D 1 135 ? 134.503 129.652 97.524  1.00 116.28 ? 225 THR D O   1 
ATOM 3818 C CB  . THR D 1 135 ? 133.290 130.462 94.503  1.00 116.28 ? 225 THR D CB  1 
ATOM 3819 O OG1 . THR D 1 135 ? 133.061 131.477 93.520  1.00 116.28 ? 225 THR D OG1 1 
ATOM 3820 C CG2 . THR D 1 135 ? 131.979 130.086 95.141  1.00 116.28 ? 225 THR D CG2 1 
ATOM 3821 N N   . ASP D 1 136 ? 135.812 129.160 95.768  1.00 121.42 ? 226 ASP D N   1 
ATOM 3822 C CA  . ASP D 1 136 ? 136.393 127.992 96.410  1.00 121.42 ? 226 ASP D CA  1 
ATOM 3823 C C   . ASP D 1 136 ? 137.118 128.363 97.689  1.00 121.42 ? 226 ASP D C   1 
ATOM 3824 O O   . ASP D 1 136 ? 136.963 127.692 98.717  1.00 121.42 ? 226 ASP D O   1 
ATOM 3825 C CB  . ASP D 1 136 ? 137.354 127.303 95.453  1.00 121.42 ? 226 ASP D CB  1 
ATOM 3826 C CG  . ASP D 1 136 ? 137.961 126.059 96.048  1.00 121.42 ? 226 ASP D CG  1 
ATOM 3827 O OD1 . ASP D 1 136 ? 139.016 126.181 96.701  1.00 121.42 ? 226 ASP D OD1 1 
ATOM 3828 O OD2 . ASP D 1 136 ? 137.389 124.963 95.875  1.00 121.42 ? 226 ASP D OD2 1 
ATOM 3829 N N   . GLU D 1 137 ? 137.927 129.416 97.637  1.00 123.04 ? 227 GLU D N   1 
ATOM 3830 C CA  . GLU D 1 137 ? 138.724 129.780 98.802  1.00 123.04 ? 227 GLU D CA  1 
ATOM 3831 C C   . GLU D 1 137 ? 137.835 130.296 99.927  1.00 123.04 ? 227 GLU D C   1 
ATOM 3832 O O   . GLU D 1 137 ? 138.089 130.031 101.105 1.00 123.04 ? 227 GLU D O   1 
ATOM 3833 C CB  . GLU D 1 137 ? 139.784 130.811 98.420  1.00 123.04 ? 227 GLU D CB  1 
ATOM 3834 C CG  . GLU D 1 137 ? 141.062 130.209 97.841  1.00 123.04 ? 227 GLU D CG  1 
ATOM 3835 C CD  . GLU D 1 137 ? 141.953 129.568 98.893  1.00 123.04 ? 227 GLU D CD  1 
ATOM 3836 O OE1 . GLU D 1 137 ? 142.968 128.950 98.515  1.00 123.04 ? 227 GLU D OE1 1 
ATOM 3837 O OE2 . GLU D 1 137 ? 141.637 129.674 100.096 1.00 123.04 ? 227 GLU D OE2 1 
ATOM 3838 N N   . ARG D 1 138 ? 136.774 131.027 99.582  1.00 113.72 ? 228 ARG D N   1 
ATOM 3839 C CA  . ARG D 1 138 ? 135.814 131.416 100.610 1.00 113.72 ? 228 ARG D CA  1 
ATOM 3840 C C   . ARG D 1 138 ? 135.130 130.195 101.208 1.00 113.72 ? 228 ARG D C   1 
ATOM 3841 O O   . ARG D 1 138 ? 134.845 130.156 102.412 1.00 113.72 ? 228 ARG D O   1 
ATOM 3842 C CB  . ARG D 1 138 ? 134.787 132.380 100.026 1.00 113.72 ? 228 ARG D CB  1 
ATOM 3843 C CG  . ARG D 1 138 ? 135.281 133.804 99.909  1.00 113.72 ? 228 ARG D CG  1 
ATOM 3844 C CD  . ARG D 1 138 ? 134.668 134.516 98.719  1.00 113.72 ? 228 ARG D CD  1 
ATOM 3845 N NE  . ARG D 1 138 ? 134.588 135.951 98.953  1.00 113.72 ? 228 ARG D NE  1 
ATOM 3846 C CZ  . ARG D 1 138 ? 133.455 136.609 99.159  1.00 113.72 ? 228 ARG D CZ  1 
ATOM 3847 N NH1 . ARG D 1 138 ? 132.297 135.962 99.140  1.00 113.72 ? 228 ARG D NH1 1 
ATOM 3848 N NH2 . ARG D 1 138 ? 133.478 137.914 99.372  1.00 113.72 ? 228 ARG D NH2 1 
ATOM 3849 N N   . LEU D 1 139 ? 134.832 129.197 100.379 1.00 106.77 ? 229 LEU D N   1 
ATOM 3850 C CA  . LEU D 1 139 ? 134.257 127.972 100.910 1.00 106.77 ? 229 LEU D CA  1 
ATOM 3851 C C   . LEU D 1 139 ? 135.216 127.314 101.884 1.00 106.77 ? 229 LEU D C   1 
ATOM 3852 O O   . LEU D 1 139 ? 134.803 126.819 102.937 1.00 106.77 ? 229 LEU D O   1 
ATOM 3853 C CB  . LEU D 1 139 ? 133.904 127.025 99.772  1.00 106.77 ? 229 LEU D CB  1 
ATOM 3854 C CG  . LEU D 1 139 ? 132.788 127.588 98.907  1.00 106.77 ? 229 LEU D CG  1 
ATOM 3855 C CD1 . LEU D 1 139 ? 132.786 126.899 97.575  1.00 106.77 ? 229 LEU D CD1 1 
ATOM 3856 C CD2 . LEU D 1 139 ? 131.448 127.456 99.586  1.00 106.77 ? 229 LEU D CD2 1 
ATOM 3857 N N   . GLU D 1 140 ? 136.503 127.318 101.557 1.00 118.23 ? 230 GLU D N   1 
ATOM 3858 C CA  . GLU D 1 140 ? 137.483 126.807 102.506 1.00 118.23 ? 230 GLU D CA  1 
ATOM 3859 C C   . GLU D 1 140 ? 137.506 127.642 103.773 1.00 118.23 ? 230 GLU D C   1 
ATOM 3860 O O   . GLU D 1 140 ? 137.720 127.107 104.865 1.00 118.23 ? 230 GLU D O   1 
ATOM 3861 C CB  . GLU D 1 140 ? 138.880 126.778 101.888 1.00 118.23 ? 230 GLU D CB  1 
ATOM 3862 C CG  . GLU D 1 140 ? 139.888 126.017 102.742 1.00 118.23 ? 230 GLU D CG  1 
ATOM 3863 C CD  . GLU D 1 140 ? 141.229 125.836 102.065 1.00 118.23 ? 230 GLU D CD  1 
ATOM 3864 O OE1 . GLU D 1 140 ? 141.391 126.314 100.923 1.00 118.23 ? 230 GLU D OE1 1 
ATOM 3865 O OE2 . GLU D 1 140 ? 142.117 125.204 102.671 1.00 118.23 ? 230 GLU D OE2 1 
ATOM 3866 N N   . ASN D 1 141 ? 137.333 128.953 103.629 1.00 121.25 ? 231 ASN D N   1 
ATOM 3867 C CA  . ASN D 1 141 ? 137.205 129.827 104.786 1.00 121.25 ? 231 ASN D CA  1 
ATOM 3868 C C   . ASN D 1 141 ? 136.085 129.352 105.691 1.00 121.25 ? 231 ASN D C   1 
ATOM 3869 O O   . ASN D 1 141 ? 136.256 129.243 106.911 1.00 121.25 ? 231 ASN D O   1 
ATOM 3870 C CB  . ASN D 1 141 ? 136.944 131.257 104.326 1.00 121.25 ? 231 ASN D CB  1 
ATOM 3871 C CG  . ASN D 1 141 ? 138.165 132.132 104.435 1.00 121.25 ? 231 ASN D CG  1 
ATOM 3872 O OD1 . ASN D 1 141 ? 138.715 132.580 103.426 1.00 121.25 ? 231 ASN D OD1 1 
ATOM 3873 N ND2 . ASN D 1 141 ? 138.607 132.381 105.666 1.00 121.25 ? 231 ASN D ND2 1 
ATOM 3874 N N   . LEU D 1 142 ? 134.931 129.064 105.102 1.00 111.56 ? 232 LEU D N   1 
ATOM 3875 C CA  . LEU D 1 142 ? 133.829 128.515 105.879 1.00 111.56 ? 232 LEU D CA  1 
ATOM 3876 C C   . LEU D 1 142 ? 134.241 127.211 106.544 1.00 111.56 ? 232 LEU D C   1 
ATOM 3877 O O   . LEU D 1 142 ? 134.017 127.011 107.743 1.00 111.56 ? 232 LEU D O   1 
ATOM 3878 C CB  . LEU D 1 142 ? 132.615 128.318 104.983 1.00 111.56 ? 232 LEU D CB  1 
ATOM 3879 C CG  . LEU D 1 142 ? 131.963 129.652 104.640 1.00 111.56 ? 232 LEU D CG  1 
ATOM 3880 C CD1 . LEU D 1 142 ? 131.103 129.486 103.436 1.00 111.56 ? 232 LEU D CD1 1 
ATOM 3881 C CD2 . LEU D 1 142 ? 131.135 130.156 105.798 1.00 111.56 ? 232 LEU D CD2 1 
ATOM 3882 N N   . LEU D 1 143 ? 134.857 126.313 105.775 1.00 112.53 ? 233 LEU D N   1 
ATOM 3883 C CA  . LEU D 1 143 ? 135.250 125.019 106.315 1.00 112.53 ? 233 LEU D CA  1 
ATOM 3884 C C   . LEU D 1 143 ? 136.106 125.157 107.559 1.00 112.53 ? 233 LEU D C   1 
ATOM 3885 O O   . LEU D 1 143 ? 135.745 124.640 108.624 1.00 112.53 ? 233 LEU D O   1 
ATOM 3886 C CB  . LEU D 1 143 ? 136.000 124.211 105.263 1.00 112.53 ? 233 LEU D CB  1 
ATOM 3887 C CG  . LEU D 1 143 ? 135.145 123.524 104.197 1.00 112.53 ? 233 LEU D CG  1 
ATOM 3888 C CD1 . LEU D 1 143 ? 135.609 122.090 104.058 1.00 112.53 ? 233 LEU D CD1 1 
ATOM 3889 C CD2 . LEU D 1 143 ? 133.670 123.569 104.533 1.00 112.53 ? 233 LEU D CD2 1 
ATOM 3890 N N   . ASN D 1 144 ? 137.227 125.863 107.461 1.00 120.46 ? 234 ASN D N   1 
ATOM 3891 C CA  . ASN D 1 144 ? 138.115 125.882 108.615 1.00 120.46 ? 234 ASN D CA  1 
ATOM 3892 C C   . ASN D 1 144 ? 137.514 126.695 109.751 1.00 120.46 ? 234 ASN D C   1 
ATOM 3893 O O   . ASN D 1 144 ? 137.684 126.335 110.921 1.00 120.46 ? 234 ASN D O   1 
ATOM 3894 C CB  . ASN D 1 144 ? 139.518 126.394 108.260 1.00 120.46 ? 234 ASN D CB  1 
ATOM 3895 C CG  . ASN D 1 144 ? 139.503 127.680 107.479 1.00 120.46 ? 234 ASN D CG  1 
ATOM 3896 O OD1 . ASN D 1 144 ? 138.453 128.194 107.143 1.00 120.46 ? 234 ASN D OD1 1 
ATOM 3897 N ND2 . ASN D 1 144 ? 140.683 128.212 107.190 1.00 120.46 ? 234 ASN D ND2 1 
ATOM 3898 N N   . ILE D 1 145 ? 136.789 127.778 109.444 1.00 113.46 ? 235 ILE D N   1 
ATOM 3899 C CA  . ILE D 1 145 ? 136.248 128.568 110.539 1.00 113.46 ? 235 ILE D CA  1 
ATOM 3900 C C   . ILE D 1 145 ? 135.249 127.747 111.334 1.00 113.46 ? 235 ILE D C   1 
ATOM 3901 O O   . ILE D 1 145 ? 135.272 127.743 112.573 1.00 113.46 ? 235 ILE D O   1 
ATOM 3902 C CB  . ILE D 1 145 ? 135.649 129.892 110.027 1.00 113.46 ? 235 ILE D CB  1 
ATOM 3903 C CG1 . ILE D 1 145 ? 135.482 130.864 111.194 1.00 113.46 ? 235 ILE D CG1 1 
ATOM 3904 C CG2 . ILE D 1 145 ? 134.314 129.684 109.341 1.00 113.46 ? 235 ILE D CG2 1 
ATOM 3905 C CD1 . ILE D 1 145 ? 135.181 132.273 110.774 1.00 113.46 ? 235 ILE D CD1 1 
ATOM 3906 N N   . VAL D 1 146 ? 134.409 126.977 110.650 1.00 103.97 ? 236 VAL D N   1 
ATOM 3907 C CA  . VAL D 1 146 ? 133.444 126.182 111.386 1.00 103.97 ? 236 VAL D CA  1 
ATOM 3908 C C   . VAL D 1 146 ? 134.138 125.013 112.069 1.00 103.97 ? 236 VAL D C   1 
ATOM 3909 O O   . VAL D 1 146 ? 133.683 124.532 113.111 1.00 103.97 ? 236 VAL D O   1 
ATOM 3910 C CB  . VAL D 1 146 ? 132.301 125.735 110.464 1.00 103.97 ? 236 VAL D CB  1 
ATOM 3911 C CG1 . VAL D 1 146 ? 131.705 126.945 109.788 1.00 103.97 ? 236 VAL D CG1 1 
ATOM 3912 C CG2 . VAL D 1 146 ? 132.805 124.761 109.444 1.00 103.97 ? 236 VAL D CG2 1 
ATOM 3913 N N   . ARG D 1 147 ? 135.265 124.557 111.520 1.00 110.85 ? 237 ARG D N   1 
ATOM 3914 C CA  . ARG D 1 147 ? 136.049 123.575 112.261 1.00 110.85 ? 237 ARG D CA  1 
ATOM 3915 C C   . ARG D 1 147 ? 136.489 124.131 113.606 1.00 110.85 ? 237 ARG D C   1 
ATOM 3916 O O   . ARG D 1 147 ? 136.294 123.489 114.649 1.00 110.85 ? 237 ARG D O   1 
ATOM 3917 C CB  . ARG D 1 147 ? 137.266 123.130 111.458 1.00 110.85 ? 237 ARG D CB  1 
ATOM 3918 C CG  . ARG D 1 147 ? 137.039 121.917 110.598 1.00 110.85 ? 237 ARG D CG  1 
ATOM 3919 C CD  . ARG D 1 147 ? 138.322 121.559 109.901 1.00 110.85 ? 237 ARG D CD  1 
ATOM 3920 N NE  . ARG D 1 147 ? 138.109 120.544 108.886 1.00 110.85 ? 237 ARG D NE  1 
ATOM 3921 C CZ  . ARG D 1 147 ? 138.408 120.708 107.605 1.00 110.85 ? 237 ARG D CZ  1 
ATOM 3922 N NH1 . ARG D 1 147 ? 138.937 121.851 107.189 1.00 110.85 ? 237 ARG D NH1 1 
ATOM 3923 N NH2 . ARG D 1 147 ? 138.178 119.731 106.742 1.00 110.85 ? 237 ARG D NH2 1 
ATOM 3924 N N   . GLU D 1 148 ? 137.100 125.317 113.599 1.00 109.85 ? 238 GLU D N   1 
ATOM 3925 C CA  . GLU D 1 148 ? 137.512 125.910 114.863 1.00 109.85 ? 238 GLU D CA  1 
ATOM 3926 C C   . GLU D 1 148 ? 136.328 126.093 115.786 1.00 109.85 ? 238 GLU D C   1 
ATOM 3927 O O   . GLU D 1 148 ? 136.454 125.902 116.999 1.00 109.85 ? 238 GLU D O   1 
ATOM 3928 C CB  . GLU D 1 148 ? 138.218 127.251 114.667 1.00 109.85 ? 238 GLU D CB  1 
ATOM 3929 C CG  . GLU D 1 148 ? 139.602 127.162 114.063 1.00 109.85 ? 238 GLU D CG  1 
ATOM 3930 C CD  . GLU D 1 148 ? 139.645 127.599 112.621 1.00 109.85 ? 238 GLU D CD  1 
ATOM 3931 O OE1 . GLU D 1 148 ? 138.715 128.308 112.203 1.00 109.85 ? 238 GLU D OE1 1 
ATOM 3932 O OE2 . GLU D 1 148 ? 140.604 127.237 111.906 1.00 109.85 ? 238 GLU D OE2 1 
ATOM 3933 N N   . ILE D 1 149 ? 135.178 126.471 115.239 1.00 95.17  ? 239 ILE D N   1 
ATOM 3934 C CA  . ILE D 1 149 ? 134.008 126.652 116.086 1.00 95.17  ? 239 ILE D CA  1 
ATOM 3935 C C   . ILE D 1 149 ? 133.623 125.335 116.740 1.00 95.17  ? 239 ILE D C   1 
ATOM 3936 O O   . ILE D 1 149 ? 133.318 125.281 117.937 1.00 95.17  ? 239 ILE D O   1 
ATOM 3937 C CB  . ILE D 1 149 ? 132.846 127.246 115.281 1.00 95.17  ? 239 ILE D CB  1 
ATOM 3938 C CG1 . ILE D 1 149 ? 133.137 128.703 114.967 1.00 95.17  ? 239 ILE D CG1 1 
ATOM 3939 C CG2 . ILE D 1 149 ? 131.574 127.164 116.078 1.00 95.17  ? 239 ILE D CG2 1 
ATOM 3940 C CD1 . ILE D 1 149 ? 131.960 129.433 114.422 1.00 95.17  ? 239 ILE D CD1 1 
ATOM 3941 N N   . LEU D 1 150 ? 133.629 124.252 115.965 1.00 90.70  ? 240 LEU D N   1 
ATOM 3942 C CA  . LEU D 1 150 ? 133.297 122.956 116.539 1.00 90.70  ? 240 LEU D CA  1 
ATOM 3943 C C   . LEU D 1 150 ? 134.260 122.592 117.650 1.00 90.70  ? 240 LEU D C   1 
ATOM 3944 O O   . LEU D 1 150 ? 133.841 122.098 118.702 1.00 90.70  ? 240 LEU D O   1 
ATOM 3945 C CB  . LEU D 1 150 ? 133.298 121.876 115.460 1.00 90.70  ? 240 LEU D CB  1 
ATOM 3946 C CG  . LEU D 1 150 ? 132.848 120.476 115.896 1.00 90.70  ? 240 LEU D CG  1 
ATOM 3947 C CD1 . LEU D 1 150 ? 132.045 119.801 114.801 1.00 90.70  ? 240 LEU D CD1 1 
ATOM 3948 C CD2 . LEU D 1 150 ? 134.040 119.611 116.256 1.00 90.70  ? 240 LEU D CD2 1 
ATOM 3949 N N   . ASP D 1 151 ? 135.550 122.840 117.442 1.00 105.61 ? 241 ASP D N   1 
ATOM 3950 C CA  . ASP D 1 151 ? 136.522 122.512 118.478 1.00 105.61 ? 241 ASP D CA  1 
ATOM 3951 C C   . ASP D 1 151 ? 136.297 123.358 119.725 1.00 105.61 ? 241 ASP D C   1 
ATOM 3952 O O   . ASP D 1 151 ? 136.366 122.857 120.858 1.00 105.61 ? 241 ASP D O   1 
ATOM 3953 C CB  . ASP D 1 151 ? 137.940 122.700 117.945 1.00 105.61 ? 241 ASP D CB  1 
ATOM 3954 C CG  . ASP D 1 151 ? 138.984 122.091 118.854 1.00 105.61 ? 241 ASP D CG  1 
ATOM 3955 O OD1 . ASP D 1 151 ? 138.697 121.040 119.463 1.00 105.61 ? 241 ASP D OD1 1 
ATOM 3956 O OD2 . ASP D 1 151 ? 140.092 122.658 118.957 1.00 105.61 ? 241 ASP D OD2 1 
ATOM 3957 N N   . VAL D 1 152 ? 136.032 124.651 119.532 1.00 90.31  ? 242 VAL D N   1 
ATOM 3958 C CA  . VAL D 1 152 ? 135.808 125.544 120.661 1.00 90.31  ? 242 VAL D CA  1 
ATOM 3959 C C   . VAL D 1 152 ? 134.590 125.101 121.449 1.00 90.31  ? 242 VAL D C   1 
ATOM 3960 O O   . VAL D 1 152 ? 134.581 125.143 122.683 1.00 90.31  ? 242 VAL D O   1 
ATOM 3961 C CB  . VAL D 1 152 ? 135.674 126.995 120.167 1.00 90.31  ? 242 VAL D CB  1 
ATOM 3962 C CG1 . VAL D 1 152 ? 134.985 127.843 121.203 1.00 90.31  ? 242 VAL D CG1 1 
ATOM 3963 C CG2 . VAL D 1 152 ? 137.042 127.564 119.863 1.00 90.31  ? 242 VAL D CG2 1 
ATOM 3964 N N   . GLN D 1 153 ? 133.552 124.642 120.757 1.00 87.75  ? 243 GLN D N   1 
ATOM 3965 C CA  . GLN D 1 153 ? 132.362 124.184 121.460 1.00 87.75  ? 243 GLN D CA  1 
ATOM 3966 C C   . GLN D 1 153 ? 132.629 122.885 122.199 1.00 87.75  ? 243 GLN D C   1 
ATOM 3967 O O   . GLN D 1 153 ? 132.143 122.685 123.317 1.00 87.75  ? 243 GLN D O   1 
ATOM 3968 C CB  . GLN D 1 153 ? 131.205 124.028 120.483 1.00 87.75  ? 243 GLN D CB  1 
ATOM 3969 C CG  . GLN D 1 153 ? 130.678 125.353 119.989 1.00 87.75  ? 243 GLN D CG  1 
ATOM 3970 C CD  . GLN D 1 153 ? 130.800 126.441 121.033 1.00 87.75  ? 243 GLN D CD  1 
ATOM 3971 O OE1 . GLN D 1 153 ? 131.773 127.195 121.059 1.00 87.75  ? 243 GLN D OE1 1 
ATOM 3972 N NE2 . GLN D 1 153 ? 129.821 126.510 121.918 1.00 87.75  ? 243 GLN D NE2 1 
ATOM 3973 N N   . ARG D 1 154 ? 133.393 121.983 121.586 1.00 92.27  ? 244 ARG D N   1 
ATOM 3974 C CA  . ARG D 1 154 ? 133.848 120.801 122.305 1.00 92.27  ? 244 ARG D CA  1 
ATOM 3975 C C   . ARG D 1 154 ? 134.500 121.186 123.626 1.00 92.27  ? 244 ARG D C   1 
ATOM 3976 O O   . ARG D 1 154 ? 134.105 120.702 124.699 1.00 92.27  ? 244 ARG D O   1 
ATOM 3977 C CB  . ARG D 1 154 ? 134.827 120.019 121.438 1.00 92.27  ? 244 ARG D CB  1 
ATOM 3978 C CG  . ARG D 1 154 ? 135.684 119.038 122.207 1.00 92.27  ? 244 ARG D CG  1 
ATOM 3979 C CD  . ARG D 1 154 ? 136.656 118.314 121.291 1.00 92.27  ? 244 ARG D CD  1 
ATOM 3980 N NE  . ARG D 1 154 ? 135.979 117.599 120.214 1.00 92.27  ? 244 ARG D NE  1 
ATOM 3981 C CZ  . ARG D 1 154 ? 135.978 117.985 118.941 1.00 92.27  ? 244 ARG D CZ  1 
ATOM 3982 N NH1 . ARG D 1 154 ? 136.619 119.088 118.579 1.00 92.27  ? 244 ARG D NH1 1 
ATOM 3983 N NH2 . ARG D 1 154 ? 135.335 117.266 118.033 1.00 92.27  ? 244 ARG D NH2 1 
ATOM 3984 N N   . ASP D 1 155 ? 135.497 122.057 123.537 1.00 89.18  ? 245 ASP D N   1 
ATOM 3985 C CA  . ASP D 1 155 ? 136.202 122.493 124.728 1.00 89.18  ? 245 ASP D CA  1 
ATOM 3986 C C   . ASP D 1 155 ? 135.230 123.049 125.741 1.00 89.18  ? 245 ASP D C   1 
ATOM 3987 O O   . ASP D 1 155 ? 135.193 122.608 126.887 1.00 89.18  ? 245 ASP D O   1 
ATOM 3988 C CB  . ASP D 1 155 ? 137.221 123.562 124.356 1.00 89.18  ? 245 ASP D CB  1 
ATOM 3989 C CG  . ASP D 1 155 ? 138.090 123.154 123.185 1.00 89.18  ? 245 ASP D CG  1 
ATOM 3990 O OD1 . ASP D 1 155 ? 138.162 121.943 122.885 1.00 89.18  ? 245 ASP D OD1 1 
ATOM 3991 O OD2 . ASP D 1 155 ? 138.702 124.046 122.562 1.00 89.18  ? 245 ASP D OD2 1 
ATOM 3992 N N   . MET D 1 156 ? 134.443 124.033 125.323 1.00 76.73  ? 246 MET D N   1 
ATOM 3993 C CA  . MET D 1 156 ? 133.509 124.647 126.255 1.00 76.73  ? 246 MET D CA  1 
ATOM 3994 C C   . MET D 1 156 ? 132.665 123.597 126.947 1.00 76.73  ? 246 MET D C   1 
ATOM 3995 O O   . MET D 1 156 ? 132.405 123.700 128.147 1.00 76.73  ? 246 MET D O   1 
ATOM 3996 C CB  . MET D 1 156 ? 132.607 125.650 125.546 1.00 76.73  ? 246 MET D CB  1 
ATOM 3997 C CG  . MET D 1 156 ? 133.206 127.019 125.380 1.00 76.73  ? 246 MET D CG  1 
ATOM 3998 S SD  . MET D 1 156 ? 131.950 128.195 124.861 1.00 76.73  ? 246 MET D SD  1 
ATOM 3999 C CE  . MET D 1 156 ? 130.942 128.268 126.336 1.00 76.73  ? 246 MET D CE  1 
ATOM 4000 N N   . ARG D 1 157 ? 132.190 122.603 126.203 1.00 71.77  ? 247 ARG D N   1 
ATOM 4001 C CA  . ARG D 1 157 ? 131.420 121.550 126.841 1.00 71.77  ? 247 ARG D CA  1 
ATOM 4002 C C   . ARG D 1 157 ? 132.237 120.872 127.924 1.00 71.77  ? 247 ARG D C   1 
ATOM 4003 O O   . ARG D 1 157 ? 131.727 120.592 129.017 1.00 71.77  ? 247 ARG D O   1 
ATOM 4004 C CB  . ARG D 1 157 ? 130.956 120.529 125.817 1.00 71.77  ? 247 ARG D CB  1 
ATOM 4005 C CG  . ARG D 1 157 ? 130.820 119.158 126.420 1.00 71.77  ? 247 ARG D CG  1 
ATOM 4006 C CD  . ARG D 1 157 ? 130.083 118.227 125.514 1.00 71.77  ? 247 ARG D CD  1 
ATOM 4007 N NE  . ARG D 1 157 ? 128.649 118.301 125.740 1.00 71.77  ? 247 ARG D NE  1 
ATOM 4008 C CZ  . ARG D 1 157 ? 127.793 117.362 125.358 1.00 71.77  ? 247 ARG D CZ  1 
ATOM 4009 N NH1 . ARG D 1 157 ? 128.228 116.278 124.732 1.00 71.77  ? 247 ARG D NH1 1 
ATOM 4010 N NH2 . ARG D 1 157 ? 126.504 117.508 125.600 1.00 71.77  ? 247 ARG D NH2 1 
ATOM 4011 N N   . ASN D 1 158 ? 133.510 120.607 127.640 1.00 76.41  ? 248 ASN D N   1 
ATOM 4012 C CA  . ASN D 1 158 ? 134.367 120.013 128.663 1.00 76.41  ? 248 ASN D CA  1 
ATOM 4013 C C   . ASN D 1 158 ? 134.483 120.931 129.874 1.00 76.41  ? 248 ASN D C   1 
ATOM 4014 O O   . ASN D 1 158 ? 134.404 120.482 131.028 1.00 76.41  ? 248 ASN D O   1 
ATOM 4015 C CB  . ASN D 1 158 ? 135.742 119.704 128.080 1.00 76.41  ? 248 ASN D CB  1 
ATOM 4016 C CG  . ASN D 1 158 ? 135.728 118.485 127.191 1.00 76.41  ? 248 ASN D CG  1 
ATOM 4017 O OD1 . ASN D 1 158 ? 134.970 117.546 127.426 1.00 76.41  ? 248 ASN D OD1 1 
ATOM 4018 N ND2 . ASN D 1 158 ? 136.564 118.490 126.160 1.00 76.41  ? 248 ASN D ND2 1 
ATOM 4019 N N   . ASP D 1 159 ? 134.652 122.226 129.628 1.00 65.32  ? 249 ASP D N   1 
ATOM 4020 C CA  . ASP D 1 159 ? 134.748 123.182 130.720 1.00 65.32  ? 249 ASP D CA  1 
ATOM 4021 C C   . ASP D 1 159 ? 133.486 123.180 131.572 1.00 65.32  ? 249 ASP D C   1 
ATOM 4022 O O   . ASP D 1 159 ? 133.560 123.225 132.806 1.00 65.32  ? 249 ASP D O   1 
ATOM 4023 C CB  . ASP D 1 159 ? 135.012 124.569 130.144 1.00 65.32  ? 249 ASP D CB  1 
ATOM 4024 C CG  . ASP D 1 159 ? 135.614 125.514 131.152 1.00 65.32  ? 249 ASP D CG  1 
ATOM 4025 O OD1 . ASP D 1 159 ? 136.784 125.306 131.524 1.00 65.32  ? 249 ASP D OD1 1 
ATOM 4026 O OD2 . ASP D 1 159 ? 134.935 126.479 131.554 1.00 65.32  ? 249 ASP D OD2 1 
ATOM 4027 N N   . LEU D 1 160 ? 132.325 123.104 130.932 1.00 54.73  ? 250 LEU D N   1 
ATOM 4028 C CA  . LEU D 1 160 ? 131.072 123.142 131.671 1.00 54.73  ? 250 LEU D CA  1 
ATOM 4029 C C   . LEU D 1 160 ? 130.888 121.879 132.491 1.00 54.73  ? 250 LEU D C   1 
ATOM 4030 O O   . LEU D 1 160 ? 130.412 121.937 133.629 1.00 54.73  ? 250 LEU D O   1 
ATOM 4031 C CB  . LEU D 1 160 ? 129.907 123.330 130.711 1.00 54.73  ? 250 LEU D CB  1 
ATOM 4032 C CG  . LEU D 1 160 ? 128.749 124.064 131.355 1.00 54.73  ? 250 LEU D CG  1 
ATOM 4033 C CD1 . LEU D 1 160 ? 129.247 125.395 131.833 1.00 54.73  ? 250 LEU D CD1 1 
ATOM 4034 C CD2 . LEU D 1 160 ? 127.650 124.254 130.359 1.00 54.73  ? 250 LEU D CD2 1 
ATOM 4035 N N   . SER D 1 161 ? 131.235 120.726 131.924 1.00 59.98  ? 251 SER D N   1 
ATOM 4036 C CA  . SER D 1 161 ? 131.269 119.513 132.729 1.00 59.98  ? 251 SER D CA  1 
ATOM 4037 C C   . SER D 1 161 ? 132.141 119.699 133.959 1.00 59.98  ? 251 SER D C   1 
ATOM 4038 O O   . SER D 1 161 ? 131.749 119.309 135.072 1.00 59.98  ? 251 SER D O   1 
ATOM 4039 C CB  . SER D 1 161 ? 131.787 118.342 131.899 1.00 59.98  ? 251 SER D CB  1 
ATOM 4040 O OG  . SER D 1 161 ? 131.942 117.183 132.698 1.00 59.98  ? 251 SER D OG  1 
ATOM 4041 N N   . ASN D 1 162 ? 133.321 120.285 133.771 1.00 52.33  ? 252 ASN D N   1 
ATOM 4042 C CA  . ASN D 1 162 ? 134.191 120.561 134.902 1.00 52.33  ? 252 ASN D CA  1 
ATOM 4043 C C   . ASN D 1 162 ? 133.456 121.381 135.953 1.00 52.33  ? 252 ASN D C   1 
ATOM 4044 O O   . ASN D 1 162 ? 133.463 121.047 137.148 1.00 52.33  ? 252 ASN D O   1 
ATOM 4045 C CB  . ASN D 1 162 ? 135.442 121.291 134.420 1.00 52.33  ? 252 ASN D CB  1 
ATOM 4046 C CG  . ASN D 1 162 ? 136.678 120.906 135.195 1.00 52.33  ? 252 ASN D CG  1 
ATOM 4047 O OD1 . ASN D 1 162 ? 136.672 119.931 135.943 1.00 52.33  ? 252 ASN D OD1 1 
ATOM 4048 N ND2 . ASN D 1 162 ? 137.746 121.677 135.033 1.00 52.33  ? 252 ASN D ND2 1 
ATOM 4049 N N   . LEU D 1 163 ? 132.788 122.444 135.517 1.00 44.99  ? 253 LEU D N   1 
ATOM 4050 C CA  . LEU D 1 163 ? 132.152 123.332 136.478 1.00 44.99  ? 253 LEU D CA  1 
ATOM 4051 C C   . LEU D 1 163 ? 131.024 122.615 137.210 1.00 44.99  ? 253 LEU D C   1 
ATOM 4052 O O   . LEU D 1 163 ? 130.798 122.850 138.403 1.00 44.99  ? 253 LEU D O   1 
ATOM 4053 C CB  . LEU D 1 163 ? 131.626 124.582 135.782 1.00 44.99  ? 253 LEU D CB  1 
ATOM 4054 C CG  . LEU D 1 163 ? 131.325 125.737 136.734 1.00 44.99  ? 253 LEU D CG  1 
ATOM 4055 C CD1 . LEU D 1 163 ? 132.626 126.306 137.248 1.00 44.99  ? 253 LEU D CD1 1 
ATOM 4056 C CD2 . LEU D 1 163 ? 130.522 126.807 136.073 1.00 44.99  ? 253 LEU D CD2 1 
ATOM 4057 N N   . THR D 1 164 ? 130.308 121.732 136.513 1.00 44.92  ? 254 THR D N   1 
ATOM 4058 C CA  . THR D 1 164 ? 129.226 120.996 137.156 1.00 44.92  ? 254 THR D CA  1 
ATOM 4059 C C   . THR D 1 164 ? 129.766 120.105 138.257 1.00 44.92  ? 254 THR D C   1 
ATOM 4060 O O   . THR D 1 164 ? 129.258 120.109 139.390 1.00 44.92  ? 254 THR D O   1 
ATOM 4061 C CB  . THR D 1 164 ? 128.471 120.155 136.139 1.00 44.92  ? 254 THR D CB  1 
ATOM 4062 O OG1 . THR D 1 164 ? 128.049 120.989 135.062 1.00 44.92  ? 254 THR D OG1 1 
ATOM 4063 C CG2 . THR D 1 164 ? 127.256 119.546 136.780 1.00 44.92  ? 254 THR D CG2 1 
ATOM 4064 N N   . ARG D 1 165 ? 130.781 119.306 137.931 1.00 54.30  ? 255 ARG D N   1 
ATOM 4065 C CA  . ARG D 1 165 ? 131.410 118.521 138.979 1.00 54.30  ? 255 ARG D CA  1 
ATOM 4066 C C   . ARG D 1 165 ? 131.805 119.388 140.155 1.00 54.30  ? 255 ARG D C   1 
ATOM 4067 O O   . ARG D 1 165 ? 131.530 119.016 141.300 1.00 54.30  ? 255 ARG D O   1 
ATOM 4068 C CB  . ARG D 1 165 ? 132.641 117.787 138.465 1.00 54.30  ? 255 ARG D CB  1 
ATOM 4069 C CG  . ARG D 1 165 ? 132.337 116.570 137.632 1.00 54.30  ? 255 ARG D CG  1 
ATOM 4070 C CD  . ARG D 1 165 ? 133.608 115.791 137.342 1.00 54.30  ? 255 ARG D CD  1 
ATOM 4071 N NE  . ARG D 1 165 ? 134.607 116.615 136.667 1.00 54.30  ? 255 ARG D NE  1 
ATOM 4072 C CZ  . ARG D 1 165 ? 134.643 116.824 135.355 1.00 54.30  ? 255 ARG D CZ  1 
ATOM 4073 N NH1 . ARG D 1 165 ? 133.732 116.272 134.566 1.00 54.30  ? 255 ARG D NH1 1 
ATOM 4074 N NH2 . ARG D 1 165 ? 135.588 117.591 134.834 1.00 54.30  ? 255 ARG D NH2 1 
ATOM 4075 N N   . LYS D 1 166 ? 132.412 120.546 139.900 1.00 44.34  ? 256 LYS D N   1 
ATOM 4076 C CA  . LYS D 1 166 ? 132.904 121.339 141.019 1.00 44.34  ? 256 LYS D CA  1 
ATOM 4077 C C   . LYS D 1 166 ? 131.771 121.874 141.886 1.00 44.34  ? 256 LYS D C   1 
ATOM 4078 O O   . LYS D 1 166 ? 131.869 121.860 143.123 1.00 44.34  ? 256 LYS D O   1 
ATOM 4079 C CB  . LYS D 1 166 ? 133.774 122.479 140.521 1.00 44.34  ? 256 LYS D CB  1 
ATOM 4080 C CG  . LYS D 1 166 ? 135.202 122.298 140.919 1.00 44.34  ? 256 LYS D CG  1 
ATOM 4081 C CD  . LYS D 1 166 ? 136.047 123.398 140.365 1.00 44.34  ? 256 LYS D CD  1 
ATOM 4082 C CE  . LYS D 1 166 ? 137.508 123.042 140.470 1.00 44.34  ? 256 LYS D CE  1 
ATOM 4083 N NZ  . LYS D 1 166 ? 138.361 124.046 139.786 1.00 44.34  ? 256 LYS D NZ  1 
ATOM 4084 N N   . VAL D 1 167 ? 130.687 122.339 141.273 1.00 34.75  ? 257 VAL D N   1 
ATOM 4085 C CA  . VAL D 1 167 ? 129.590 122.860 142.079 1.00 34.75  ? 257 VAL D CA  1 
ATOM 4086 C C   . VAL D 1 167 ? 128.989 121.753 142.927 1.00 34.75  ? 257 VAL D C   1 
ATOM 4087 O O   . VAL D 1 167 ? 128.720 121.942 144.121 1.00 34.75  ? 257 VAL D O   1 
ATOM 4088 C CB  . VAL D 1 167 ? 128.536 123.534 141.191 1.00 34.75  ? 257 VAL D CB  1 
ATOM 4089 C CG1 . VAL D 1 167 ? 127.236 123.629 141.930 1.00 34.75  ? 257 VAL D CG1 1 
ATOM 4090 C CG2 . VAL D 1 167 ? 129.001 124.906 140.816 1.00 34.75  ? 257 VAL D CG2 1 
ATOM 4091 N N   . ASP D 1 168 ? 128.790 120.573 142.346 1.00 36.36  ? 258 ASP D N   1 
ATOM 4092 C CA  . ASP D 1 168 ? 128.224 119.496 143.146 1.00 36.36  ? 258 ASP D CA  1 
ATOM 4093 C C   . ASP D 1 168 ? 129.135 119.135 144.306 1.00 36.36  ? 258 ASP D C   1 
ATOM 4094 O O   . ASP D 1 168 ? 128.669 118.934 145.439 1.00 36.36  ? 258 ASP D O   1 
ATOM 4095 C CB  . ASP D 1 168 ? 127.960 118.279 142.278 1.00 36.36  ? 258 ASP D CB  1 
ATOM 4096 C CG  . ASP D 1 168 ? 126.518 118.162 141.907 1.00 36.36  ? 258 ASP D CG  1 
ATOM 4097 O OD1 . ASP D 1 168 ? 125.744 119.023 142.361 1.00 36.36  ? 258 ASP D OD1 1 
ATOM 4098 O OD2 . ASP D 1 168 ? 126.152 117.221 141.177 1.00 36.36  ? 258 ASP D OD2 1 
ATOM 4099 N N   . ARG D 1 169 ? 130.431 119.013 144.034 1.00 43.13  ? 259 ARG D N   1 
ATOM 4100 C CA  . ARG D 1 169 ? 131.393 118.789 145.101 1.00 43.13  ? 259 ARG D CA  1 
ATOM 4101 C C   . ARG D 1 169 ? 131.170 119.757 146.250 1.00 43.13  ? 259 ARG D C   1 
ATOM 4102 O O   . ARG D 1 169 ? 130.947 119.342 147.396 1.00 43.13  ? 259 ARG D O   1 
ATOM 4103 C CB  . ARG D 1 169 ? 132.804 118.944 144.552 1.00 43.13  ? 259 ARG D CB  1 
ATOM 4104 C CG  . ARG D 1 169 ? 133.856 119.058 145.603 1.00 43.13  ? 259 ARG D CG  1 
ATOM 4105 C CD  . ARG D 1 169 ? 134.194 117.698 146.058 1.00 43.13  ? 259 ARG D CD  1 
ATOM 4106 N NE  . ARG D 1 169 ? 134.838 116.972 144.982 1.00 43.13  ? 259 ARG D NE  1 
ATOM 4107 C CZ  . ARG D 1 169 ? 134.953 115.655 144.954 1.00 43.13  ? 259 ARG D CZ  1 
ATOM 4108 N NH1 . ARG D 1 169 ? 134.452 114.931 145.941 1.00 43.13  ? 259 ARG D NH1 1 
ATOM 4109 N NH2 . ARG D 1 169 ? 135.558 115.062 143.939 1.00 43.13  ? 259 ARG D NH2 1 
ATOM 4110 N N   . MET D 1 170 ? 131.207 121.053 145.957 1.00 37.32  ? 260 MET D N   1 
ATOM 4111 C CA  . MET D 1 170 ? 131.082 122.035 147.026 1.00 37.32  ? 260 MET D CA  1 
ATOM 4112 C C   . MET D 1 170 ? 129.764 121.864 147.767 1.00 37.32  ? 260 MET D C   1 
ATOM 4113 O O   . MET D 1 170 ? 129.688 122.076 148.984 1.00 37.32  ? 260 MET D O   1 
ATOM 4114 C CB  . MET D 1 170 ? 131.211 123.444 146.458 1.00 37.32  ? 260 MET D CB  1 
ATOM 4115 C CG  . MET D 1 170 ? 131.205 124.517 147.506 1.00 37.32  ? 260 MET D CG  1 
ATOM 4116 S SD  . MET D 1 170 ? 131.282 126.120 146.737 1.00 37.32  ? 260 MET D SD  1 
ATOM 4117 C CE  . MET D 1 170 ? 129.794 126.017 145.774 1.00 37.32  ? 260 MET D CE  1 
ATOM 4118 N N   . ASP D 1 171 ? 128.711 121.486 147.045 1.00 40.36  ? 261 ASP D N   1 
ATOM 4119 C CA  . ASP D 1 171 ? 127.429 121.268 147.701 1.00 40.36  ? 261 ASP D CA  1 
ATOM 4120 C C   . ASP D 1 171 ? 127.553 120.211 148.779 1.00 40.36  ? 261 ASP D C   1 
ATOM 4121 O O   . ASP D 1 171 ? 127.135 120.418 149.929 1.00 40.36  ? 261 ASP D O   1 
ATOM 4122 C CB  . ASP D 1 171 ? 126.381 120.854 146.675 1.00 40.36  ? 261 ASP D CB  1 
ATOM 4123 C CG  . ASP D 1 171 ? 124.990 120.814 147.252 1.00 40.36  ? 261 ASP D CG  1 
ATOM 4124 O OD1 . ASP D 1 171 ? 124.831 121.170 148.432 1.00 40.36  ? 261 ASP D OD1 1 
ATOM 4125 O OD2 . ASP D 1 171 ? 124.051 120.433 146.528 1.00 40.36  ? 261 ASP D OD2 1 
ATOM 4126 N N   . MET D 1 172 ? 128.108 119.060 148.411 1.00 35.93  ? 262 MET D N   1 
ATOM 4127 C CA  . MET D 1 172 ? 128.326 118.017 149.401 1.00 35.93  ? 262 MET D CA  1 
ATOM 4128 C C   . MET D 1 172 ? 129.110 118.565 150.580 1.00 35.93  ? 262 MET D C   1 
ATOM 4129 O O   . MET D 1 172 ? 128.762 118.322 151.744 1.00 35.93  ? 262 MET D O   1 
ATOM 4130 C CB  . MET D 1 172 ? 129.058 116.834 148.780 1.00 35.93  ? 262 MET D CB  1 
ATOM 4131 C CG  . MET D 1 172 ? 129.229 115.669 149.714 1.00 35.93  ? 262 MET D CG  1 
ATOM 4132 S SD  . MET D 1 172 ? 130.726 115.755 150.706 1.00 35.93  ? 262 MET D SD  1 
ATOM 4133 C CE  . MET D 1 172 ? 131.918 115.105 149.557 1.00 35.93  ? 262 MET D CE  1 
ATOM 4134 N N   . ARG D 1 173 ? 130.168 119.327 150.291 1.00 40.37  ? 263 ARG D N   1 
ATOM 4135 C CA  . ARG D 1 173 ? 131.046 119.796 151.361 1.00 40.37  ? 263 ARG D CA  1 
ATOM 4136 C C   . ARG D 1 173 ? 130.283 120.636 152.369 1.00 40.37  ? 263 ARG D C   1 
ATOM 4137 O O   . ARG D 1 173 ? 130.380 120.416 153.586 1.00 40.37  ? 263 ARG D O   1 
ATOM 4138 C CB  . ARG D 1 173 ? 132.215 120.601 150.796 1.00 40.37  ? 263 ARG D CB  1 
ATOM 4139 C CG  . ARG D 1 173 ? 133.183 121.035 151.880 1.00 40.37  ? 263 ARG D CG  1 
ATOM 4140 C CD  . ARG D 1 173 ? 134.270 121.937 151.365 1.00 40.37  ? 263 ARG D CD  1 
ATOM 4141 N NE  . ARG D 1 173 ? 134.824 121.459 150.110 1.00 40.37  ? 263 ARG D NE  1 
ATOM 4142 C CZ  . ARG D 1 173 ? 135.781 120.548 150.026 1.00 40.37  ? 263 ARG D CZ  1 
ATOM 4143 N NH1 . ARG D 1 173 ? 136.279 120.011 151.126 1.00 40.37  ? 263 ARG D NH1 1 
ATOM 4144 N NH2 . ARG D 1 173 ? 136.234 120.171 148.843 1.00 40.37  ? 263 ARG D NH2 1 
ATOM 4145 N N   . LEU D 1 174 ? 129.518 121.606 151.884 1.00 43.00  ? 264 LEU D N   1 
ATOM 4146 C CA  . LEU D 1 174 ? 128.852 122.496 152.823 1.00 43.00  ? 264 LEU D CA  1 
ATOM 4147 C C   . LEU D 1 174 ? 127.747 121.786 153.580 1.00 43.00  ? 264 LEU D C   1 
ATOM 4148 O O   . LEU D 1 174 ? 127.590 122.006 154.787 1.00 43.00  ? 264 LEU D O   1 
ATOM 4149 C CB  . LEU D 1 174 ? 128.310 123.729 152.118 1.00 43.00  ? 264 LEU D CB  1 
ATOM 4150 C CG  . LEU D 1 174 ? 129.349 124.815 152.376 1.00 43.00  ? 264 LEU D CG  1 
ATOM 4151 C CD1 . LEU D 1 174 ? 129.533 125.738 151.191 1.00 43.00  ? 264 LEU D CD1 1 
ATOM 4152 C CD2 . LEU D 1 174 ? 129.002 125.575 153.631 1.00 43.00  ? 264 LEU D CD2 1 
ATOM 4153 N N   . SER D 1 175 ? 126.971 120.939 152.905 1.00 41.28  ? 265 SER D N   1 
ATOM 4154 C CA  . SER D 1 175 ? 125.982 120.171 153.646 1.00 41.28  ? 265 SER D CA  1 
ATOM 4155 C C   . SER D 1 175 ? 126.630 119.426 154.801 1.00 41.28  ? 265 SER D C   1 
ATOM 4156 O O   . SER D 1 175 ? 126.158 119.496 155.949 1.00 41.28  ? 265 SER D O   1 
ATOM 4157 C CB  . SER D 1 175 ? 125.275 119.198 152.719 1.00 41.28  ? 265 SER D CB  1 
ATOM 4158 O OG  . SER D 1 175 ? 124.424 118.356 153.464 1.00 41.28  ? 265 SER D OG  1 
ATOM 4159 N N   . ARG D 1 176 ? 127.726 118.724 154.526 1.00 45.49  ? 266 ARG D N   1 
ATOM 4160 C CA  . ARG D 1 176 ? 128.386 117.996 155.597 1.00 45.49  ? 266 ARG D CA  1 
ATOM 4161 C C   . ARG D 1 176 ? 128.790 118.934 156.717 1.00 45.49  ? 266 ARG D C   1 
ATOM 4162 O O   . ARG D 1 176 ? 128.375 118.760 157.867 1.00 45.49  ? 266 ARG D O   1 
ATOM 4163 C CB  . ARG D 1 176 ? 129.619 117.269 155.083 1.00 45.49  ? 266 ARG D CB  1 
ATOM 4164 C CG  . ARG D 1 176 ? 130.451 116.701 156.213 1.00 45.49  ? 266 ARG D CG  1 
ATOM 4165 C CD  . ARG D 1 176 ? 131.872 116.475 155.782 1.00 45.49  ? 266 ARG D CD  1 
ATOM 4166 N NE  . ARG D 1 176 ? 132.417 117.642 155.116 1.00 45.49  ? 266 ARG D NE  1 
ATOM 4167 C CZ  . ARG D 1 176 ? 133.557 117.628 154.444 1.00 45.49  ? 266 ARG D CZ  1 
ATOM 4168 N NH1 . ARG D 1 176 ? 134.250 116.507 154.352 1.00 45.49  ? 266 ARG D NH1 1 
ATOM 4169 N NH2 . ARG D 1 176 ? 134.001 118.729 153.863 1.00 45.49  ? 266 ARG D NH2 1 
ATOM 4170 N N   . ASN D 1 177 ? 129.590 119.948 156.387 1.00 49.54  ? 267 ASN D N   1 
ATOM 4171 C CA  . ASN D 1 177 ? 130.174 120.778 157.430 1.00 49.54  ? 267 ASN D CA  1 
ATOM 4172 C C   . ASN D 1 177 ? 129.092 121.437 158.266 1.00 49.54  ? 267 ASN D C   1 
ATOM 4173 O O   . ASN D 1 177 ? 129.295 121.679 159.458 1.00 49.54  ? 267 ASN D O   1 
ATOM 4174 C CB  . ASN D 1 177 ? 131.125 121.813 156.825 1.00 49.54  ? 267 ASN D CB  1 
ATOM 4175 C CG  . ASN D 1 177 ? 132.230 122.227 157.793 1.00 49.54  ? 267 ASN D CG  1 
ATOM 4176 O OD1 . ASN D 1 177 ? 132.040 122.247 159.001 1.00 49.54  ? 267 ASN D OD1 1 
ATOM 4177 N ND2 . ASN D 1 177 ? 133.403 122.513 157.259 1.00 49.54  ? 267 ASN D ND2 1 
ATOM 4178 N N   . ASN D 1 178 ? 127.919 121.687 157.688 1.00 51.69  ? 268 ASN D N   1 
ATOM 4179 C CA  . ASN D 1 178 ? 126.856 122.269 158.495 1.00 51.69  ? 268 ASN D CA  1 
ATOM 4180 C C   . ASN D 1 178 ? 126.243 121.237 159.426 1.00 51.69  ? 268 ASN D C   1 
ATOM 4181 O O   . ASN D 1 178 ? 125.960 121.545 160.592 1.00 51.69  ? 268 ASN D O   1 
ATOM 4182 C CB  . ASN D 1 178 ? 125.792 122.899 157.610 1.00 51.69  ? 268 ASN D CB  1 
ATOM 4183 C CG  . ASN D 1 178 ? 125.903 124.399 157.558 1.00 51.69  ? 268 ASN D CG  1 
ATOM 4184 O OD1 . ASN D 1 178 ? 125.108 125.115 158.162 1.00 51.69  ? 268 ASN D OD1 1 
ATOM 4185 N ND2 . ASN D 1 178 ? 126.908 124.887 156.842 1.00 51.69  ? 268 ASN D ND2 1 
ATOM 4186 N N   . ASN D 1 179 ? 126.017 120.010 158.945 1.00 57.80  ? 269 ASN D N   1 
ATOM 4187 C CA  . ASN D 1 179 ? 125.633 118.974 159.897 1.00 57.80  ? 269 ASN D CA  1 
ATOM 4188 C C   . ASN D 1 179 ? 126.637 118.892 161.023 1.00 57.80  ? 269 ASN D C   1 
ATOM 4189 O O   . ASN D 1 179 ? 126.277 118.597 162.165 1.00 57.80  ? 269 ASN D O   1 
ATOM 4190 C CB  . ASN D 1 179 ? 125.492 117.603 159.244 1.00 57.80  ? 269 ASN D CB  1 
ATOM 4191 C CG  . ASN D 1 179 ? 124.080 117.320 158.770 1.00 57.80  ? 269 ASN D CG  1 
ATOM 4192 O OD1 . ASN D 1 179 ? 123.117 117.717 159.412 1.00 57.80  ? 269 ASN D OD1 1 
ATOM 4193 N ND2 . ASN D 1 179 ? 123.950 116.585 157.677 1.00 57.80  ? 269 ASN D ND2 1 
ATOM 4194 N N   . MET D 1 180 ? 127.904 119.147 160.716 1.00 60.97  ? 270 MET D N   1 
ATOM 4195 C CA  . MET D 1 180 ? 128.926 119.051 161.748 1.00 60.97  ? 270 MET D CA  1 
ATOM 4196 C C   . MET D 1 180 ? 128.634 119.986 162.916 1.00 60.97  ? 270 MET D C   1 
ATOM 4197 O O   . MET D 1 180 ? 128.474 119.521 164.050 1.00 60.97  ? 270 MET D O   1 
ATOM 4198 C CB  . MET D 1 180 ? 130.300 119.337 161.157 1.00 60.97  ? 270 MET D CB  1 
ATOM 4199 C CG  . MET D 1 180 ? 131.010 118.114 160.630 1.00 60.97  ? 270 MET D CG  1 
ATOM 4200 S SD  . MET D 1 180 ? 132.646 118.525 159.999 1.00 60.97  ? 270 MET D SD  1 
ATOM 4201 C CE  . MET D 1 180 ? 133.702 117.831 161.260 1.00 60.97  ? 270 MET D CE  1 
ATOM 4202 N N   . ILE D 1 181 ? 128.550 121.295 162.669 1.00 54.81  ? 271 ILE D N   1 
ATOM 4203 C CA  . ILE D 1 181 ? 128.212 122.210 163.754 1.00 54.81  ? 271 ILE D CA  1 
ATOM 4204 C C   . ILE D 1 181 ? 126.898 121.806 164.385 1.00 54.81  ? 271 ILE D C   1 
ATOM 4205 O O   . ILE D 1 181 ? 126.779 121.738 165.613 1.00 54.81  ? 271 ILE D O   1 
ATOM 4206 C CB  . ILE D 1 181 ? 128.139 123.659 163.255 1.00 54.81  ? 271 ILE D CB  1 
ATOM 4207 C CG1 . ILE D 1 181 ? 129.518 124.199 162.933 1.00 54.81  ? 271 ILE D CG1 1 
ATOM 4208 C CG2 . ILE D 1 181 ? 127.526 124.522 164.315 1.00 54.81  ? 271 ILE D CG2 1 
ATOM 4209 C CD1 . ILE D 1 181 ? 129.453 125.534 162.248 1.00 54.81  ? 271 ILE D CD1 1 
ATOM 4210 N N   . MET D 1 182 ? 125.896 121.518 163.555 1.00 62.09  ? 272 MET D N   1 
ATOM 4211 C CA  . MET D 1 182 ? 124.575 121.210 164.080 1.00 62.09  ? 272 MET D CA  1 
ATOM 4212 C C   . MET D 1 182 ? 124.627 120.070 165.083 1.00 62.09  ? 272 MET D C   1 
ATOM 4213 O O   . MET D 1 182 ? 123.832 120.028 166.027 1.00 62.09  ? 272 MET D O   1 
ATOM 4214 C CB  . MET D 1 182 ? 123.630 120.881 162.934 1.00 62.09  ? 272 MET D CB  1 
ATOM 4215 C CG  . MET D 1 182 ? 122.666 121.992 162.636 1.00 62.09  ? 272 MET D CG  1 
ATOM 4216 S SD  . MET D 1 182 ? 121.607 122.196 164.068 1.00 62.09  ? 272 MET D SD  1 
ATOM 4217 C CE  . MET D 1 182 ? 120.558 123.530 163.531 1.00 62.09  ? 272 MET D CE  1 
ATOM 4218 N N   . ARG D 1 183 ? 125.561 119.141 164.900 1.00 72.12  ? 273 ARG D N   1 
ATOM 4219 C CA  . ARG D 1 183 ? 125.651 118.010 165.811 1.00 72.12  ? 273 ARG D CA  1 
ATOM 4220 C C   . ARG D 1 183 ? 126.017 118.426 167.226 1.00 72.12  ? 273 ARG D C   1 
ATOM 4221 O O   . ARG D 1 183 ? 125.701 117.698 168.172 1.00 72.12  ? 273 ARG D O   1 
ATOM 4222 C CB  . ARG D 1 183 ? 126.671 117.011 165.293 1.00 72.12  ? 273 ARG D CB  1 
ATOM 4223 C CG  . ARG D 1 183 ? 126.728 115.732 166.082 1.00 72.12  ? 273 ARG D CG  1 
ATOM 4224 C CD  . ARG D 1 183 ? 125.458 114.949 165.922 1.00 72.12  ? 273 ARG D CD  1 
ATOM 4225 N NE  . ARG D 1 183 ? 125.285 114.004 167.010 1.00 72.12  ? 273 ARG D NE  1 
ATOM 4226 C CZ  . ARG D 1 183 ? 124.876 114.348 168.220 1.00 72.12  ? 273 ARG D CZ  1 
ATOM 4227 N NH1 . ARG D 1 183 ? 124.598 115.614 168.483 1.00 72.12  ? 273 ARG D NH1 1 
ATOM 4228 N NH2 . ARG D 1 183 ? 124.741 113.428 169.163 1.00 72.12  ? 273 ARG D NH2 1 
ATOM 4229 N N   . SER D 1 184 ? 126.655 119.585 167.397 1.00 68.83  ? 274 SER D N   1 
ATOM 4230 C CA  . SER D 1 184 ? 127.116 119.981 168.723 1.00 68.83  ? 274 SER D CA  1 
ATOM 4231 C C   . SER D 1 184 ? 125.967 120.311 169.662 1.00 68.83  ? 274 SER D C   1 
ATOM 4232 O O   . SER D 1 184 ? 126.175 120.420 170.873 1.00 68.83  ? 274 SER D O   1 
ATOM 4233 C CB  . SER D 1 184 ? 128.054 121.177 168.618 1.00 68.83  ? 274 SER D CB  1 
ATOM 4234 O OG  . SER D 1 184 ? 129.340 120.845 169.105 1.00 68.83  ? 274 SER D OG  1 
ATOM 4235 N N   . PHE D 1 185 ? 124.760 120.485 169.139 1.00 77.42  ? 275 PHE D N   1 
ATOM 4236 C CA  . PHE D 1 185 ? 123.632 120.889 169.960 1.00 77.42  ? 275 PHE D CA  1 
ATOM 4237 C C   . PHE D 1 185 ? 122.570 119.815 170.099 1.00 77.42  ? 275 PHE D C   1 
ATOM 4238 O O   . PHE D 1 185 ? 121.407 120.150 170.326 1.00 77.42  ? 275 PHE D O   1 
ATOM 4239 C CB  . PHE D 1 185 ? 123.006 122.157 169.396 1.00 77.42  ? 275 PHE D CB  1 
ATOM 4240 C CG  . PHE D 1 185 ? 123.847 123.361 169.595 1.00 77.42  ? 275 PHE D CG  1 
ATOM 4241 C CD1 . PHE D 1 185 ? 123.858 124.007 170.809 1.00 77.42  ? 275 PHE D CD1 1 
ATOM 4242 C CD2 . PHE D 1 185 ? 124.652 123.830 168.584 1.00 77.42  ? 275 PHE D CD2 1 
ATOM 4243 C CE1 . PHE D 1 185 ? 124.640 125.112 171.006 1.00 77.42  ? 275 PHE D CE1 1 
ATOM 4244 C CE2 . PHE D 1 185 ? 125.437 124.937 168.775 1.00 77.42  ? 275 PHE D CE2 1 
ATOM 4245 C CZ  . PHE D 1 185 ? 125.432 125.579 169.988 1.00 77.42  ? 275 PHE D CZ  1 
ATOM 4246 N N   . ARG D 1 186 ? 122.937 118.542 169.982 1.00 85.95  ? 276 ARG D N   1 
ATOM 4247 C CA  . ARG D 1 186 ? 121.976 117.442 170.041 1.00 85.95  ? 276 ARG D CA  1 
ATOM 4248 C C   . ARG D 1 186 ? 120.850 117.626 169.033 1.00 85.95  ? 276 ARG D C   1 
ATOM 4249 O O   . ARG D 1 186 ? 119.693 117.302 169.308 1.00 85.95  ? 276 ARG D O   1 
ATOM 4250 C CB  . ARG D 1 186 ? 121.399 117.314 171.452 1.00 50.00  ? 276 ARG D CB  1 
ATOM 4251 C CG  . ARG D 1 186 ? 122.411 116.880 172.499 1.00 50.00  ? 276 ARG D CG  1 
ATOM 4252 C CD  . ARG D 1 186 ? 121.828 116.707 173.893 1.00 50.00  ? 276 ARG D CD  1 
ATOM 4253 N NE  . ARG D 1 186 ? 122.850 116.358 174.875 1.00 50.00  ? 276 ARG D NE  1 
ATOM 4254 C CZ  . ARG D 1 186 ? 122.629 116.263 176.178 1.00 50.00  ? 276 ARG D CZ  1 
ATOM 4255 N NH1 . ARG D 1 186 ? 121.416 116.487 176.666 1.00 50.00  ? 276 ARG D NH1 1 
ATOM 4256 N NH2 . ARG D 1 186 ? 123.620 115.940 177.000 1.00 50.00  ? 276 ARG D NH2 1 
ATOM 4257 N N   . GLN D 1 187 ? 121.196 118.161 167.867 1.00 74.23  ? 277 GLN D N   1 
ATOM 4258 C CA  . GLN D 1 187 ? 120.202 118.372 166.827 1.00 74.23  ? 277 GLN D CA  1 
ATOM 4259 C C   . GLN D 1 187 ? 120.366 117.330 165.738 1.00 74.23  ? 277 GLN D C   1 
ATOM 4260 O O   . GLN D 1 187 ? 121.487 116.960 165.390 1.00 74.23  ? 277 GLN D O   1 
ATOM 4261 C CB  . GLN D 1 187 ? 120.351 119.764 166.225 1.00 74.23  ? 277 GLN D CB  1 
ATOM 4262 C CG  . GLN D 1 187 ? 120.537 120.866 167.250 1.00 74.23  ? 277 GLN D CG  1 
ATOM 4263 C CD  . GLN D 1 187 ? 119.340 121.027 168.167 1.00 74.23  ? 277 GLN D CD  1 
ATOM 4264 O OE1 . GLN D 1 187 ? 118.256 120.509 167.896 1.00 74.23  ? 277 GLN D OE1 1 
ATOM 4265 N NE2 . GLN D 1 187 ? 119.529 121.759 169.258 1.00 74.23  ? 277 GLN D NE2 1 
ATOM 4266 N N   . PRO D 1 188 ? 119.243 116.852 165.187 1.00 74.40  ? 278 PRO D N   1 
ATOM 4267 C CA  . PRO D 1 188 ? 119.318 115.822 164.153 1.00 74.40  ? 278 PRO D CA  1 
ATOM 4268 C C   . PRO D 1 188 ? 120.002 116.352 162.907 1.00 74.40  ? 278 PRO D C   1 
ATOM 4269 O O   . PRO D 1 188 ? 119.933 117.536 162.582 1.00 74.40  ? 278 PRO D O   1 
ATOM 4270 C CB  . PRO D 1 188 ? 117.851 115.485 163.877 1.00 74.40  ? 278 PRO D CB  1 
ATOM 4271 C CG  . PRO D 1 188 ? 117.091 116.060 165.034 1.00 74.40  ? 278 PRO D CG  1 
ATOM 4272 C CD  . PRO D 1 188 ? 117.862 117.250 165.476 1.00 74.40  ? 278 PRO D CD  1 
ATOM 4273 N N   . ILE D 1 189 ? 120.670 115.445 162.204 1.00 59.93  ? 279 ILE D N   1 
ATOM 4274 C CA  . ILE D 1 189 ? 121.356 115.771 160.963 1.00 59.93  ? 279 ILE D CA  1 
ATOM 4275 C C   . ILE D 1 189 ? 120.387 115.704 159.800 1.00 59.93  ? 279 ILE D C   1 
ATOM 4276 O O   . ILE D 1 189 ? 119.266 115.208 159.938 1.00 59.93  ? 279 ILE D O   1 
ATOM 4277 C CB  . ILE D 1 189 ? 122.529 114.820 160.722 1.00 59.93  ? 279 ILE D CB  1 
ATOM 4278 C CG1 . ILE D 1 189 ? 122.070 113.405 161.039 1.00 59.93  ? 279 ILE D CG1 1 
ATOM 4279 C CG2 . ILE D 1 189 ? 123.704 115.234 161.551 1.00 59.93  ? 279 ILE D CG2 1 
ATOM 4280 C CD1 . ILE D 1 189 ? 123.131 112.371 160.893 1.00 59.93  ? 279 ILE D CD1 1 
ATOM 4281 N N   . THR D 1 190 ? 120.815 116.199 158.649 1.00 55.36  ? 280 THR D N   1 
ATOM 4282 C CA  . THR D 1 190 ? 120.008 116.177 157.445 1.00 55.36  ? 280 THR D CA  1 
ATOM 4283 C C   . THR D 1 190 ? 120.659 115.283 156.403 1.00 55.36  ? 280 THR D C   1 
ATOM 4284 O O   . THR D 1 190 ? 121.833 114.929 156.505 1.00 55.36  ? 280 THR D O   1 
ATOM 4285 C CB  . THR D 1 190 ? 119.843 117.582 156.880 1.00 55.36  ? 280 THR D CB  1 
ATOM 4286 O OG1 . THR D 1 190 ? 120.984 117.892 156.077 1.00 55.36  ? 280 THR D OG1 1 
ATOM 4287 C CG2 . THR D 1 190 ? 119.758 118.583 158.006 1.00 55.36  ? 280 THR D CG2 1 
ATOM 4288 N N   . GLU D 1 191 ? 119.884 114.933 155.386 1.00 52.76  ? 281 GLU D N   1 
ATOM 4289 C CA  . GLU D 1 191 ? 120.362 114.073 154.308 1.00 52.76  ? 281 GLU D CA  1 
ATOM 4290 C C   . GLU D 1 191 ? 121.474 114.800 153.565 1.00 52.76  ? 281 GLU D C   1 
ATOM 4291 O O   . GLU D 1 191 ? 121.660 116.005 153.720 1.00 52.76  ? 281 GLU D O   1 
ATOM 4292 C CB  . GLU D 1 191 ? 119.209 113.707 153.382 1.00 52.76  ? 281 GLU D CB  1 
ATOM 4293 C CG  . GLU D 1 191 ? 119.479 112.552 152.423 1.00 52.76  ? 281 GLU D CG  1 
ATOM 4294 C CD  . GLU D 1 191 ? 118.266 112.186 151.574 1.00 52.76  ? 281 GLU D CD  1 
ATOM 4295 O OE1 . GLU D 1 191 ? 117.226 112.869 151.685 1.00 52.76  ? 281 GLU D OE1 1 
ATOM 4296 O OE2 . GLU D 1 191 ? 118.352 111.213 150.796 1.00 52.76  ? 281 GLU D OE2 1 
ATOM 4297 N N   . VAL D 1 192 ? 122.230 114.068 152.767 1.00 38.19  ? 282 VAL D N   1 
ATOM 4298 C CA  . VAL D 1 192 ? 123.402 114.645 152.106 1.00 38.19  ? 282 VAL D CA  1 
ATOM 4299 C C   . VAL D 1 192 ? 123.430 114.203 150.656 1.00 38.19  ? 282 VAL D C   1 
ATOM 4300 O O   . VAL D 1 192 ? 123.156 113.031 150.371 1.00 38.19  ? 282 VAL D O   1 
ATOM 4301 C CB  . VAL D 1 192 ? 124.660 114.210 152.832 1.00 38.19  ? 282 VAL D CB  1 
ATOM 4302 C CG1 . VAL D 1 192 ? 125.817 114.149 151.885 1.00 38.19  ? 282 VAL D CG1 1 
ATOM 4303 C CG2 . VAL D 1 192 ? 124.943 115.176 153.938 1.00 38.19  ? 282 VAL D CG2 1 
ATOM 4304 N N   . PRO D 1 193 ? 123.771 115.066 149.714 1.00 48.66  ? 283 PRO D N   1 
ATOM 4305 C CA  . PRO D 1 193 ? 123.737 114.664 148.312 1.00 48.66  ? 283 PRO D CA  1 
ATOM 4306 C C   . PRO D 1 193 ? 124.915 113.769 147.991 1.00 48.66  ? 283 PRO D C   1 
ATOM 4307 O O   . PRO D 1 193 ? 125.852 113.641 148.777 1.00 48.66  ? 283 PRO D O   1 
ATOM 4308 C CB  . PRO D 1 193 ? 123.833 115.988 147.550 1.00 48.66  ? 283 PRO D CB  1 
ATOM 4309 C CG  . PRO D 1 193 ? 123.814 117.053 148.594 1.00 48.66  ? 283 PRO D CG  1 
ATOM 4310 C CD  . PRO D 1 193 ? 124.279 116.429 149.859 1.00 48.66  ? 283 PRO D CD  1 
ATOM 4311 N N   . PHE D 1 194 ? 124.858 113.152 146.818 1.00 55.37  ? 284 PHE D N   1 
ATOM 4312 C CA  . PHE D 1 194 ? 125.955 112.323 146.364 1.00 55.37  ? 284 PHE D CA  1 
ATOM 4313 C C   . PHE D 1 194 ? 126.896 113.123 145.471 1.00 55.37  ? 284 PHE D C   1 
ATOM 4314 O O   . PHE D 1 194 ? 126.532 114.138 144.876 1.00 55.37  ? 284 PHE D O   1 
ATOM 4315 C CB  . PHE D 1 194 ? 125.433 111.104 145.614 1.00 55.37  ? 284 PHE D CB  1 
ATOM 4316 C CG  . PHE D 1 194 ? 125.013 109.990 146.507 1.00 55.37  ? 284 PHE D CG  1 
ATOM 4317 C CD1 . PHE D 1 194 ? 125.439 109.947 147.811 1.00 55.37  ? 284 PHE D CD1 1 
ATOM 4318 C CD2 . PHE D 1 194 ? 124.201 108.982 146.044 1.00 55.37  ? 284 PHE D CD2 1 
ATOM 4319 C CE1 . PHE D 1 194 ? 125.057 108.926 148.633 1.00 55.37  ? 284 PHE D CE1 1 
ATOM 4320 C CE2 . PHE D 1 194 ? 123.826 107.958 146.862 1.00 55.37  ? 284 PHE D CE2 1 
ATOM 4321 C CZ  . PHE D 1 194 ? 124.249 107.931 148.158 1.00 55.37  ? 284 PHE D CZ  1 
ATOM 4322 N N   . PHE D 1 195 ? 128.116 112.615 145.354 1.00 53.40  ? 285 PHE D N   1 
ATOM 4323 C CA  . PHE D 1 195 ? 129.192 113.252 144.614 1.00 53.40  ? 285 PHE D CA  1 
ATOM 4324 C C   . PHE D 1 195 ? 128.778 113.627 143.195 1.00 53.40  ? 285 PHE D C   1 
ATOM 4325 O O   . PHE D 1 195 ? 129.443 114.434 142.546 1.00 53.40  ? 285 PHE D O   1 
ATOM 4326 C CB  . PHE D 1 195 ? 130.395 112.313 144.617 1.00 53.40  ? 285 PHE D CB  1 
ATOM 4327 C CG  . PHE D 1 195 ? 131.329 112.516 143.478 1.00 53.40  ? 285 PHE D CG  1 
ATOM 4328 C CD1 . PHE D 1 195 ? 131.344 111.630 142.420 1.00 53.40  ? 285 PHE D CD1 1 
ATOM 4329 C CD2 . PHE D 1 195 ? 132.212 113.572 143.471 1.00 53.40  ? 285 PHE D CD2 1 
ATOM 4330 C CE1 . PHE D 1 195 ? 132.208 111.804 141.365 1.00 53.40  ? 285 PHE D CE1 1 
ATOM 4331 C CE2 . PHE D 1 195 ? 133.080 113.749 142.418 1.00 53.40  ? 285 PHE D CE2 1 
ATOM 4332 C CZ  . PHE D 1 195 ? 133.078 112.863 141.363 1.00 53.40  ? 285 PHE D CZ  1 
ATOM 4333 N N   . ASN D 1 196 ? 127.671 113.076 142.707 1.00 49.58  ? 286 ASN D N   1 
ATOM 4334 C CA  . ASN D 1 196 ? 127.165 113.403 141.383 1.00 49.58  ? 286 ASN D CA  1 
ATOM 4335 C C   . ASN D 1 196 ? 125.884 114.216 141.427 1.00 49.58  ? 286 ASN D C   1 
ATOM 4336 O O   . ASN D 1 196 ? 125.381 114.612 140.373 1.00 49.58  ? 286 ASN D O   1 
ATOM 4337 C CB  . ASN D 1 196 ? 126.931 112.128 140.587 1.00 49.58  ? 286 ASN D CB  1 
ATOM 4338 C CG  . ASN D 1 196 ? 125.757 111.344 141.108 1.00 49.58  ? 286 ASN D CG  1 
ATOM 4339 O OD1 . ASN D 1 196 ? 125.504 111.329 142.309 1.00 49.58  ? 286 ASN D OD1 1 
ATOM 4340 N ND2 . ASN D 1 196 ? 125.039 110.679 140.217 1.00 49.58  ? 286 ASN D ND2 1 
ATOM 4341 N N   . GLY D 1 197 ? 125.331 114.463 142.613 1.00 55.15  ? 287 GLY D N   1 
ATOM 4342 C CA  . GLY D 1 197 ? 124.220 115.381 142.767 1.00 55.15  ? 287 GLY D CA  1 
ATOM 4343 C C   . GLY D 1 197 ? 122.889 114.785 143.178 1.00 55.15  ? 287 GLY D C   1 
ATOM 4344 O O   . GLY D 1 197 ? 122.181 115.400 143.986 1.00 55.15  ? 287 GLY D O   1 
ATOM 4345 N N   . ASP D 1 198 ? 122.522 113.617 142.661 1.00 62.87  ? 288 ASP D N   1 
ATOM 4346 C CA  . ASP D 1 198 ? 121.232 113.007 142.942 1.00 62.87  ? 288 ASP D CA  1 
ATOM 4347 C C   . ASP D 1 198 ? 121.046 112.812 144.436 1.00 62.87  ? 288 ASP D C   1 
ATOM 4348 O O   . ASP D 1 198 ? 121.996 112.853 145.216 1.00 62.87  ? 288 ASP D O   1 
ATOM 4349 C CB  . ASP D 1 198 ? 121.108 111.652 142.254 1.00 62.87  ? 288 ASP D CB  1 
ATOM 4350 C CG  . ASP D 1 198 ? 121.557 111.690 140.821 1.00 62.87  ? 288 ASP D CG  1 
ATOM 4351 O OD1 . ASP D 1 198 ? 121.249 112.685 140.135 1.00 62.87  ? 288 ASP D OD1 1 
ATOM 4352 O OD2 . ASP D 1 198 ? 122.215 110.727 140.376 1.00 62.87  ? 288 ASP D OD2 1 
ATOM 4353 N N   . ILE D 1 199 ? 119.801 112.605 144.833 1.00 61.63  ? 289 ILE D N   1 
ATOM 4354 C CA  . ILE D 1 199 ? 119.532 112.135 146.185 1.00 61.63  ? 289 ILE D CA  1 
ATOM 4355 C C   . ILE D 1 199 ? 119.839 110.647 146.172 1.00 61.63  ? 289 ILE D C   1 
ATOM 4356 O O   . ILE D 1 199 ? 119.750 110.014 145.111 1.00 61.63  ? 289 ILE D O   1 
ATOM 4357 C CB  . ILE D 1 199 ? 118.096 112.462 146.620 1.00 61.63  ? 289 ILE D CB  1 
ATOM 4358 C CG1 . ILE D 1 199 ? 118.117 113.490 147.759 1.00 61.63  ? 289 ILE D CG1 1 
ATOM 4359 C CG2 . ILE D 1 199 ? 117.349 111.216 147.040 1.00 61.63  ? 289 ILE D CG2 1 
ATOM 4360 C CD1 . ILE D 1 199 ? 117.463 114.818 147.409 1.00 61.63  ? 289 ILE D CD1 1 
ATOM 4361 N N   . PRO D 1 200 ? 120.250 110.061 147.293 1.00 72.56  ? 290 PRO D N   1 
ATOM 4362 C CA  . PRO D 1 200 ? 120.609 108.641 147.306 1.00 72.56  ? 290 PRO D CA  1 
ATOM 4363 C C   . PRO D 1 200 ? 119.466 107.759 146.833 1.00 72.56  ? 290 PRO D C   1 
ATOM 4364 O O   . PRO D 1 200 ? 118.346 108.222 146.616 1.00 72.56  ? 290 PRO D O   1 
ATOM 4365 C CB  . PRO D 1 200 ? 120.936 108.376 148.777 1.00 72.56  ? 290 PRO D CB  1 
ATOM 4366 C CG  . PRO D 1 200 ? 121.309 109.681 149.314 1.00 72.56  ? 290 PRO D CG  1 
ATOM 4367 C CD  . PRO D 1 200 ? 120.482 110.694 148.597 1.00 72.56  ? 290 PRO D CD  1 
ATOM 4368 N N   . ASP D 1 201 ? 119.758 106.474 146.666 1.00 100.01 ? 291 ASP D N   1 
ATOM 4369 C CA  . ASP D 1 201 ? 118.714 105.539 146.299 1.00 100.01 ? 291 ASP D CA  1 
ATOM 4370 C C   . ASP D 1 201 ? 117.615 105.562 147.365 1.00 100.01 ? 291 ASP D C   1 
ATOM 4371 O O   . ASP D 1 201 ? 117.877 105.189 148.516 1.00 100.01 ? 291 ASP D O   1 
ATOM 4372 C CB  . ASP D 1 201 ? 119.253 104.126 146.143 1.00 100.01 ? 291 ASP D CB  1 
ATOM 4373 C CG  . ASP D 1 201 ? 118.201 103.167 145.632 1.00 100.01 ? 291 ASP D CG  1 
ATOM 4374 O OD1 . ASP D 1 201 ? 118.301 102.746 144.461 1.00 100.01 ? 291 ASP D OD1 1 
ATOM 4375 O OD2 . ASP D 1 201 ? 117.262 102.857 146.388 1.00 100.01 ? 291 ASP D OD2 1 
ATOM 4376 N N   . PRO D 1 202 ? 116.402 105.980 147.019 1.00 101.77 ? 292 PRO D N   1 
ATOM 4377 C CA  . PRO D 1 202 ? 115.378 106.188 148.056 1.00 101.77 ? 292 PRO D CA  1 
ATOM 4378 C C   . PRO D 1 202 ? 115.012 104.930 148.809 1.00 101.77 ? 292 PRO D C   1 
ATOM 4379 O O   . PRO D 1 202 ? 114.338 105.022 149.842 1.00 101.77 ? 292 PRO D O   1 
ATOM 4380 C CB  . PRO D 1 202 ? 114.185 106.735 147.263 1.00 101.77 ? 292 PRO D CB  1 
ATOM 4381 C CG  . PRO D 1 202 ? 114.775 107.239 145.976 1.00 101.77 ? 292 PRO D CG  1 
ATOM 4382 C CD  . PRO D 1 202 ? 115.909 106.321 145.679 1.00 101.77 ? 292 PRO D CD  1 
ATOM 4383 N N   . ASN D 1 203 ? 115.422 103.759 148.335 1.00 114.73 ? 293 ASN D N   1 
ATOM 4384 C CA  . ASN D 1 203 ? 115.363 102.563 149.157 1.00 114.73 ? 293 ASN D CA  1 
ATOM 4385 C C   . ASN D 1 203 ? 116.448 102.544 150.221 1.00 114.73 ? 293 ASN D C   1 
ATOM 4386 O O   . ASN D 1 203 ? 116.344 101.776 151.182 1.00 114.73 ? 293 ASN D O   1 
ATOM 4387 C CB  . ASN D 1 203 ? 115.493 101.310 148.291 1.00 114.73 ? 293 ASN D CB  1 
ATOM 4388 C CG  . ASN D 1 203 ? 115.403 100.037 149.096 1.00 114.73 ? 293 ASN D CG  1 
ATOM 4389 O OD1 . ASN D 1 203 ? 114.682 99.967  150.090 1.00 114.73 ? 293 ASN D OD1 1 
ATOM 4390 N ND2 . ASN D 1 203 ? 116.168 99.030  148.694 1.00 114.73 ? 293 ASN D ND2 1 
ATOM 4391 N N   . LEU D 1 204 ? 117.467 103.381 150.091 1.00 99.90  ? 294 LEU D N   1 
ATOM 4392 C CA  . LEU D 1 204 ? 118.545 103.346 151.056 1.00 99.90  ? 294 LEU D CA  1 
ATOM 4393 C C   . LEU D 1 204 ? 118.199 104.239 152.242 1.00 99.90  ? 294 LEU D C   1 
ATOM 4394 O O   . LEU D 1 204 ? 117.877 105.417 152.074 1.00 99.90  ? 294 LEU D O   1 
ATOM 4395 C CB  . LEU D 1 204 ? 119.856 103.785 150.421 1.00 99.90  ? 294 LEU D CB  1 
ATOM 4396 C CG  . LEU D 1 204 ? 120.608 102.720 149.611 1.00 99.90  ? 294 LEU D CG  1 
ATOM 4397 C CD1 . LEU D 1 204 ? 121.676 102.077 150.471 1.00 99.90  ? 294 LEU D CD1 1 
ATOM 4398 C CD2 . LEU D 1 204 ? 119.700 101.650 149.012 1.00 99.90  ? 294 LEU D CD2 1 
ATOM 4399 N N   . PRO D 1 205 ? 118.259 103.699 153.436 1.00 97.15  ? 295 PRO D N   1 
ATOM 4400 C CA  . PRO D 1 205 ? 117.654 104.372 154.590 1.00 97.15  ? 295 PRO D CA  1 
ATOM 4401 C C   . PRO D 1 205 ? 118.295 105.710 154.878 1.00 97.15  ? 295 PRO D C   1 
ATOM 4402 O O   . PRO D 1 205 ? 119.521 105.820 154.902 1.00 97.15  ? 295 PRO D O   1 
ATOM 4403 C CB  . PRO D 1 205 ? 117.893 103.385 155.739 1.00 97.15  ? 295 PRO D CB  1 
ATOM 4404 C CG  . PRO D 1 205 ? 118.346 102.110 155.087 1.00 97.15  ? 295 PRO D CG  1 
ATOM 4405 C CD  . PRO D 1 205 ? 119.004 102.496 153.818 1.00 97.15  ? 295 PRO D CD  1 
ATOM 4406 N N   . ARG D 1 206 ? 117.479 106.736 155.079 1.00 89.40  ? 296 ARG D N   1 
ATOM 4407 C CA  . ARG D 1 206 ? 118.001 108.049 155.436 1.00 89.40  ? 296 ARG D CA  1 
ATOM 4408 C C   . ARG D 1 206 ? 118.672 107.981 156.803 1.00 89.40  ? 296 ARG D C   1 
ATOM 4409 O O   . ARG D 1 206 ? 118.339 107.127 157.629 1.00 89.40  ? 296 ARG D O   1 
ATOM 4410 C CB  . ARG D 1 206 ? 116.883 109.081 155.411 1.00 89.40  ? 296 ARG D CB  1 
ATOM 4411 C CG  . ARG D 1 206 ? 116.506 109.512 154.011 1.00 89.40  ? 296 ARG D CG  1 
ATOM 4412 C CD  . ARG D 1 206 ? 115.061 109.946 153.929 1.00 89.40  ? 296 ARG D CD  1 
ATOM 4413 N NE  . ARG D 1 206 ? 114.810 110.720 152.720 1.00 89.40  ? 296 ARG D NE  1 
ATOM 4414 C CZ  . ARG D 1 206 ? 114.324 111.956 152.717 1.00 89.40  ? 296 ARG D CZ  1 
ATOM 4415 N NH1 . ARG D 1 206 ? 114.019 112.548 153.862 1.00 89.40  ? 296 ARG D NH1 1 
ATOM 4416 N NH2 . ARG D 1 206 ? 114.133 112.594 151.573 1.00 89.40  ? 296 ARG D NH2 1 
ATOM 4417 N N   . ILE D 1 207 ? 119.622 108.883 157.038 1.00 85.68  ? 297 ILE D N   1 
ATOM 4418 C CA  . ILE D 1 207 ? 120.533 108.790 158.174 1.00 85.68  ? 297 ILE D CA  1 
ATOM 4419 C C   . ILE D 1 207 ? 120.193 109.908 159.151 1.00 85.68  ? 297 ILE D C   1 
ATOM 4420 O O   . ILE D 1 207 ? 120.020 111.060 158.747 1.00 85.68  ? 297 ILE D O   1 
ATOM 4421 C CB  . ILE D 1 207 ? 121.984 108.887 157.712 1.00 85.68  ? 297 ILE D CB  1 
ATOM 4422 C CG1 . ILE D 1 207 ? 122.154 108.079 156.435 1.00 85.68  ? 297 ILE D CG1 1 
ATOM 4423 C CG2 . ILE D 1 207 ? 122.899 108.362 158.779 1.00 85.68  ? 297 ILE D CG2 1 
ATOM 4424 C CD1 . ILE D 1 207 ? 123.320 108.514 155.607 1.00 85.68  ? 297 ILE D CD1 1 
ATOM 4425 N N   . THR D 1 208 ? 120.110 109.584 160.441 1.00 91.30  ? 298 THR D N   1 
ATOM 4426 C CA  . THR D 1 208 ? 119.741 110.573 161.443 1.00 91.30  ? 298 THR D CA  1 
ATOM 4427 C C   . THR D 1 208 ? 120.687 110.631 162.624 1.00 91.30  ? 298 THR D C   1 
ATOM 4428 O O   . THR D 1 208 ? 120.816 111.692 163.239 1.00 91.30  ? 298 THR D O   1 
ATOM 4429 C CB  . THR D 1 208 ? 118.342 110.292 161.998 1.00 91.30  ? 298 THR D CB  1 
ATOM 4430 O OG1 . THR D 1 208 ? 118.361 109.044 162.700 1.00 91.30  ? 298 THR D OG1 1 
ATOM 4431 C CG2 . THR D 1 208 ? 117.328 110.220 160.875 1.00 91.30  ? 298 THR D CG2 1 
ATOM 4432 N N   . ARG D 1 209 ? 121.313 109.519 162.980 1.00 104.97 ? 299 ARG D N   1 
ATOM 4433 C CA  . ARG D 1 209 ? 122.228 109.484 164.101 1.00 104.97 ? 299 ARG D CA  1 
ATOM 4434 C C   . ARG D 1 209 ? 123.097 108.246 163.981 1.00 104.97 ? 299 ARG D C   1 
ATOM 4435 O O   . ARG D 1 209 ? 123.013 107.489 163.011 1.00 104.97 ? 299 ARG D O   1 
ATOM 4436 C CB  . ARG D 1 209 ? 121.472 109.528 165.428 1.00 104.97 ? 299 ARG D CB  1 
ATOM 4437 C CG  . ARG D 1 209 ? 120.168 108.775 165.419 1.00 104.97 ? 299 ARG D CG  1 
ATOM 4438 C CD  . ARG D 1 209 ? 119.382 109.130 166.657 1.00 104.97 ? 299 ARG D CD  1 
ATOM 4439 N NE  . ARG D 1 209 ? 119.361 110.574 166.872 1.00 104.97 ? 299 ARG D NE  1 
ATOM 4440 C CZ  . ARG D 1 209 ? 118.972 111.154 168.002 1.00 104.97 ? 299 ARG D CZ  1 
ATOM 4441 N NH1 . ARG D 1 209 ? 118.568 110.412 169.024 1.00 104.97 ? 299 ARG D NH1 1 
ATOM 4442 N NH2 . ARG D 1 209 ? 118.985 112.475 168.113 1.00 104.97 ? 299 ARG D NH2 1 
ATOM 4443 N N   . ILE D 1 210 ? 123.922 108.030 164.997 1.00 111.10 ? 300 ILE D N   1 
ATOM 4444 C CA  . ILE D 1 210 ? 125.037 107.120 164.819 1.00 111.10 ? 300 ILE D CA  1 
ATOM 4445 C C   . ILE D 1 210 ? 124.581 105.669 164.827 1.00 111.10 ? 300 ILE D C   1 
ATOM 4446 O O   . ILE D 1 210 ? 125.000 104.881 163.970 1.00 111.10 ? 300 ILE D O   1 
ATOM 4447 C CB  . ILE D 1 210 ? 126.096 107.407 165.891 1.00 111.10 ? 300 ILE D CB  1 
ATOM 4448 C CG1 . ILE D 1 210 ? 127.239 106.406 165.789 1.00 111.10 ? 300 ILE D CG1 1 
ATOM 4449 C CG2 . ILE D 1 210 ? 125.476 107.401 167.275 1.00 111.10 ? 300 ILE D CG2 1 
ATOM 4450 C CD1 . ILE D 1 210 ? 128.507 106.909 166.405 1.00 111.10 ? 300 ILE D CD1 1 
ATOM 4451 N N   . GLU D 1 211 ? 123.715 105.291 165.764 1.00 113.05 ? 301 GLU D N   1 
ATOM 4452 C CA  . GLU D 1 211 ? 123.268 103.906 165.834 1.00 113.05 ? 301 GLU D CA  1 
ATOM 4453 C C   . GLU D 1 211 ? 122.587 103.483 164.541 1.00 113.05 ? 301 GLU D C   1 
ATOM 4454 O O   . GLU D 1 211 ? 122.637 102.306 164.158 1.00 113.05 ? 301 GLU D O   1 
ATOM 4455 C CB  . GLU D 1 211 ? 122.331 103.730 167.026 1.00 113.05 ? 301 GLU D CB  1 
ATOM 4456 C CG  . GLU D 1 211 ? 120.983 104.406 166.865 1.00 113.05 ? 301 GLU D CG  1 
ATOM 4457 C CD  . GLU D 1 211 ? 121.025 105.881 167.203 1.00 113.05 ? 301 GLU D CD  1 
ATOM 4458 O OE1 . GLU D 1 211 ? 122.015 106.559 166.850 1.00 113.05 ? 301 GLU D OE1 1 
ATOM 4459 O OE2 . GLU D 1 211 ? 120.072 106.355 167.852 1.00 113.05 ? 301 GLU D OE2 1 
ATOM 4460 N N   . ASP D 1 212 ? 121.944 104.432 163.857 1.00 117.00 ? 302 ASP D N   1 
ATOM 4461 C CA  . ASP D 1 212 ? 121.404 104.153 162.534 1.00 117.00 ? 302 ASP D CA  1 
ATOM 4462 C C   . ASP D 1 212 ? 122.463 103.537 161.641 1.00 117.00 ? 302 ASP D C   1 
ATOM 4463 O O   . ASP D 1 212 ? 122.237 102.493 161.018 1.00 117.00 ? 302 ASP D O   1 
ATOM 4464 C CB  . ASP D 1 212 ? 120.859 105.434 161.910 1.00 117.00 ? 302 ASP D CB  1 
ATOM 4465 C CG  . ASP D 1 212 ? 120.376 105.229 160.488 1.00 117.00 ? 302 ASP D CG  1 
ATOM 4466 O OD1 . ASP D 1 212 ? 119.454 104.411 160.278 1.00 117.00 ? 302 ASP D OD1 1 
ATOM 4467 O OD2 . ASP D 1 212 ? 120.922 105.891 159.580 1.00 117.00 ? 302 ASP D OD2 1 
ATOM 4468 N N   . ILE D 1 213 ? 123.630 104.168 161.572 1.00 109.52 ? 303 ILE D N   1 
ATOM 4469 C CA  . ILE D 1 213 ? 124.739 103.564 160.855 1.00 109.52 ? 303 ILE D CA  1 
ATOM 4470 C C   . ILE D 1 213 ? 125.108 102.235 161.485 1.00 109.52 ? 303 ILE D C   1 
ATOM 4471 O O   . ILE D 1 213 ? 125.191 101.209 160.802 1.00 109.52 ? 303 ILE D O   1 
ATOM 4472 C CB  . ILE D 1 213 ? 125.937 104.520 160.830 1.00 109.52 ? 303 ILE D CB  1 
ATOM 4473 C CG1 . ILE D 1 213 ? 125.550 105.820 160.142 1.00 109.52 ? 303 ILE D CG1 1 
ATOM 4474 C CG2 . ILE D 1 213 ? 127.092 103.872 160.123 1.00 109.52 ? 303 ILE D CG2 1 
ATOM 4475 C CD1 . ILE D 1 213 ? 126.724 106.551 159.554 1.00 109.52 ? 303 ILE D CD1 1 
ATOM 4476 N N   . ASP D 1 214 ? 125.311 102.224 162.804 1.00 117.42 ? 304 ASP D N   1 
ATOM 4477 C CA  . ASP D 1 214 ? 125.849 101.039 163.463 1.00 117.42 ? 304 ASP D CA  1 
ATOM 4478 C C   . ASP D 1 214 ? 124.971 99.815  163.268 1.00 117.42 ? 304 ASP D C   1 
ATOM 4479 O O   . ASP D 1 214 ? 125.396 98.705  163.600 1.00 117.42 ? 304 ASP D O   1 
ATOM 4480 C CB  . ASP D 1 214 ? 126.045 101.292 164.957 1.00 117.42 ? 304 ASP D CB  1 
ATOM 4481 C CG  . ASP D 1 214 ? 127.188 100.476 165.539 1.00 117.42 ? 304 ASP D CG  1 
ATOM 4482 O OD1 . ASP D 1 214 ? 127.980 99.910  164.759 1.00 117.42 ? 304 ASP D OD1 1 
ATOM 4483 O OD2 . ASP D 1 214 ? 127.295 100.386 166.777 1.00 117.42 ? 304 ASP D OD2 1 
ATOM 4484 N N   . SER D 1 215 ? 123.760 99.994  162.753 1.00 118.85 ? 305 SER D N   1 
ATOM 4485 C CA  . SER D 1 215 ? 122.878 98.870  162.480 1.00 118.85 ? 305 SER D CA  1 
ATOM 4486 C C   . SER D 1 215 ? 122.823 98.497  161.008 1.00 118.85 ? 305 SER D C   1 
ATOM 4487 O O   . SER D 1 215 ? 122.093 97.569  160.648 1.00 118.85 ? 305 SER D O   1 
ATOM 4488 C CB  . SER D 1 215 ? 121.469 99.191  162.973 1.00 118.85 ? 305 SER D CB  1 
ATOM 4489 O OG  . SER D 1 215 ? 120.556 99.271  161.894 1.00 118.85 ? 305 SER D OG  1 
ATOM 4490 N N   . LEU D 1 216 ? 123.569 99.183  160.153 1.00 112.35 ? 306 LEU D N   1 
ATOM 4491 C CA  . LEU D 1 216 ? 123.387 99.020  158.720 1.00 112.35 ? 306 LEU D CA  1 
ATOM 4492 C C   . LEU D 1 216 ? 124.044 97.737  158.224 1.00 112.35 ? 306 LEU D C   1 
ATOM 4493 O O   . LEU D 1 216 ? 124.919 97.171  158.883 1.00 112.35 ? 306 LEU D O   1 
ATOM 4494 C CB  . LEU D 1 216 ? 123.963 100.226 157.988 1.00 112.35 ? 306 LEU D CB  1 
ATOM 4495 C CG  . LEU D 1 216 ? 123.644 100.321 156.500 1.00 112.35 ? 306 LEU D CG  1 
ATOM 4496 C CD1 . LEU D 1 216 ? 122.166 100.047 156.278 1.00 112.35 ? 306 LEU D CD1 1 
ATOM 4497 C CD2 . LEU D 1 216 ? 124.032 101.673 155.946 1.00 112.35 ? 306 LEU D CD2 1 
ATOM 4498 N N   . SER D 1 217 ? 123.604 97.272  157.055 1.00 112.99 ? 307 SER D N   1 
ATOM 4499 C CA  . SER D 1 217 ? 124.205 96.115  156.410 1.00 112.99 ? 307 SER D CA  1 
ATOM 4500 C C   . SER D 1 217 ? 125.491 96.505  155.693 1.00 112.99 ? 307 SER D C   1 
ATOM 4501 O O   . SER D 1 217 ? 125.713 97.665  155.336 1.00 112.99 ? 307 SER D O   1 
ATOM 4502 C CB  . SER D 1 217 ? 123.238 95.493  155.407 1.00 112.99 ? 307 SER D CB  1 
ATOM 4503 O OG  . SER D 1 217 ? 123.718 95.668  154.088 1.00 112.99 ? 307 SER D OG  1 
ATOM 4504 N N   . GLU D 1 218 ? 126.341 95.502  155.467 1.00 114.64 ? 308 GLU D N   1 
ATOM 4505 C CA  . GLU D 1 218 ? 127.660 95.764  154.903 1.00 114.64 ? 308 GLU D CA  1 
ATOM 4506 C C   . GLU D 1 218 ? 127.555 96.272  153.470 1.00 114.64 ? 308 GLU D C   1 
ATOM 4507 O O   . GLU D 1 218 ? 128.207 97.258  153.105 1.00 114.64 ? 308 GLU D O   1 
ATOM 4508 C CB  . GLU D 1 218 ? 128.525 94.498  155.031 1.00 114.64 ? 308 GLU D CB  1 
ATOM 4509 C CG  . GLU D 1 218 ? 129.725 94.252  154.082 1.00 114.64 ? 308 GLU D CG  1 
ATOM 4510 C CD  . GLU D 1 218 ? 129.406 94.300  152.598 1.00 114.64 ? 308 GLU D CD  1 
ATOM 4511 O OE1 . GLU D 1 218 ? 128.432 93.642  152.188 1.00 114.64 ? 308 GLU D OE1 1 
ATOM 4512 O OE2 . GLU D 1 218 ? 130.116 95.001  151.860 1.00 114.64 ? 308 GLU D OE2 1 
ATOM 4513 N N   . GLU D 1 219 ? 126.756 95.606  152.640 1.00 112.61 ? 309 GLU D N   1 
ATOM 4514 C CA  . GLU D 1 219 ? 126.638 96.049  151.256 1.00 112.61 ? 309 GLU D CA  1 
ATOM 4515 C C   . GLU D 1 219 ? 126.138 97.481  151.195 1.00 112.61 ? 309 GLU D C   1 
ATOM 4516 O O   . GLU D 1 219 ? 126.582 98.270  150.356 1.00 112.61 ? 309 GLU D O   1 
ATOM 4517 C CB  . GLU D 1 219 ? 125.721 95.113  150.477 1.00 112.61 ? 309 GLU D CB  1 
ATOM 4518 C CG  . GLU D 1 219 ? 124.442 94.765  151.201 1.00 112.61 ? 309 GLU D CG  1 
ATOM 4519 C CD  . GLU D 1 219 ? 123.373 95.819  151.036 1.00 112.61 ? 309 GLU D CD  1 
ATOM 4520 O OE1 . GLU D 1 219 ? 123.489 96.645  150.109 1.00 112.61 ? 309 GLU D OE1 1 
ATOM 4521 O OE2 . GLU D 1 219 ? 122.429 95.833  151.849 1.00 112.61 ? 309 GLU D OE2 1 
ATOM 4522 N N   . ASN D 1 220 ? 125.222 97.838  152.090 1.00 102.91 ? 310 ASN D N   1 
ATOM 4523 C CA  . ASN D 1 220 ? 124.752 99.212  152.132 1.00 102.91 ? 310 ASN D CA  1 
ATOM 4524 C C   . ASN D 1 220 ? 125.870 100.151 152.541 1.00 102.91 ? 310 ASN D C   1 
ATOM 4525 O O   . ASN D 1 220 ? 125.958 101.279 152.043 1.00 102.91 ? 310 ASN D O   1 
ATOM 4526 C CB  . ASN D 1 220 ? 123.577 99.328  153.091 1.00 102.91 ? 310 ASN D CB  1 
ATOM 4527 C CG  . ASN D 1 220 ? 122.306 98.785  152.506 1.00 102.91 ? 310 ASN D CG  1 
ATOM 4528 O OD1 . ASN D 1 220 ? 122.062 98.912  151.307 1.00 102.91 ? 310 ASN D OD1 1 
ATOM 4529 N ND2 . ASN D 1 220 ? 121.480 98.178  153.345 1.00 102.91 ? 310 ASN D ND2 1 
ATOM 4530 N N   . CYS D 1 221 ? 126.719 99.712  153.466 1.00 101.89 ? 311 CYS D N   1 
ATOM 4531 C CA  . CYS D 1 221 ? 127.877 100.514 153.827 1.00 101.89 ? 311 CYS D CA  1 
ATOM 4532 C C   . CYS D 1 221 ? 128.732 100.797 152.605 1.00 101.89 ? 311 CYS D C   1 
ATOM 4533 O O   . CYS D 1 221 ? 129.149 101.936 152.371 1.00 101.89 ? 311 CYS D O   1 
ATOM 4534 C CB  . CYS D 1 221 ? 128.694 99.800  154.899 1.00 101.89 ? 311 CYS D CB  1 
ATOM 4535 S SG  . CYS D 1 221 ? 130.371 100.435 155.089 1.00 101.89 ? 311 CYS D SG  1 
ATOM 4536 N N   . THR D 1 222 ? 129.013 99.764  151.820 1.00 93.48  ? 312 THR D N   1 
ATOM 4537 C CA  . THR D 1 222 ? 129.789 99.976  150.609 1.00 93.48  ? 312 THR D CA  1 
ATOM 4538 C C   . THR D 1 222 ? 129.081 100.922 149.663 1.00 93.48  ? 312 THR D C   1 
ATOM 4539 O O   . THR D 1 222 ? 129.712 101.821 149.096 1.00 93.48  ? 312 THR D O   1 
ATOM 4540 C CB  . THR D 1 222 ? 130.058 98.648  149.920 1.00 93.48  ? 312 THR D CB  1 
ATOM 4541 O OG1 . THR D 1 222 ? 128.816 97.968  149.717 1.00 93.48  ? 312 THR D OG1 1 
ATOM 4542 C CG2 . THR D 1 222 ? 130.979 97.797  150.765 1.00 93.48  ? 312 THR D CG2 1 
ATOM 4543 N N   . ARG D 1 223 ? 127.784 100.718 149.461 1.00 85.73  ? 313 ARG D N   1 
ATOM 4544 C CA  . ARG D 1 223 ? 127.020 101.632 148.627 1.00 85.73  ? 313 ARG D CA  1 
ATOM 4545 C C   . ARG D 1 223 ? 127.262 103.065 149.062 1.00 85.73  ? 313 ARG D C   1 
ATOM 4546 O O   . ARG D 1 223 ? 127.727 103.895 148.277 1.00 85.73  ? 313 ARG D O   1 
ATOM 4547 C CB  . ARG D 1 223 ? 125.533 101.294 148.700 1.00 85.73  ? 313 ARG D CB  1 
ATOM 4548 C CG  . ARG D 1 223 ? 125.180 99.945  148.123 1.00 85.73  ? 313 ARG D CG  1 
ATOM 4549 C CD  . ARG D 1 223 ? 123.682 99.769  148.037 1.00 85.73  ? 313 ARG D CD  1 
ATOM 4550 N NE  . ARG D 1 223 ? 123.077 100.835 147.253 1.00 85.73  ? 313 ARG D NE  1 
ATOM 4551 C CZ  . ARG D 1 223 ? 121.897 100.737 146.658 1.00 85.73  ? 313 ARG D CZ  1 
ATOM 4552 N NH1 . ARG D 1 223 ? 121.196 99.618  146.755 1.00 85.73  ? 313 ARG D NH1 1 
ATOM 4553 N NH2 . ARG D 1 223 ? 121.419 101.757 145.965 1.00 85.73  ? 313 ARG D NH2 1 
ATOM 4554 N N   . TYR D 1 224 ? 126.974 103.358 150.326 1.00 77.25  ? 314 TYR D N   1 
ATOM 4555 C CA  . TYR D 1 224 ? 127.234 104.686 150.852 1.00 77.25  ? 314 TYR D CA  1 
ATOM 4556 C C   . TYR D 1 224 ? 128.641 105.143 150.521 1.00 77.25  ? 314 TYR D C   1 
ATOM 4557 O O   . TYR D 1 224 ? 128.826 106.152 149.835 1.00 77.25  ? 314 TYR D O   1 
ATOM 4558 C CB  . TYR D 1 224 ? 127.000 104.708 152.356 1.00 77.25  ? 314 TYR D CB  1 
ATOM 4559 C CG  . TYR D 1 224 ? 125.626 105.172 152.751 1.00 77.25  ? 314 TYR D CG  1 
ATOM 4560 C CD1 . TYR D 1 224 ? 124.939 106.088 151.975 1.00 77.25  ? 314 TYR D CD1 1 
ATOM 4561 C CD2 . TYR D 1 224 ? 125.024 104.707 153.900 1.00 77.25  ? 314 TYR D CD2 1 
ATOM 4562 C CE1 . TYR D 1 224 ? 123.704 106.529 152.335 1.00 77.25  ? 314 TYR D CE1 1 
ATOM 4563 C CE2 . TYR D 1 224 ? 123.788 105.137 154.264 1.00 77.25  ? 314 TYR D CE2 1 
ATOM 4564 C CZ  . TYR D 1 224 ? 123.131 106.045 153.474 1.00 77.25  ? 314 TYR D CZ  1 
ATOM 4565 O OH  . TYR D 1 224 ? 121.882 106.475 153.836 1.00 77.25  ? 314 TYR D OH  1 
ATOM 4566 N N   . LEU D 1 225 ? 129.644 104.397 150.976 1.00 78.59  ? 315 LEU D N   1 
ATOM 4567 C CA  . LEU D 1 225 ? 131.021 104.819 150.765 1.00 78.59  ? 315 LEU D CA  1 
ATOM 4568 C C   . LEU D 1 225 ? 131.261 105.182 149.315 1.00 78.59  ? 315 LEU D C   1 
ATOM 4569 O O   . LEU D 1 225 ? 132.032 106.097 149.010 1.00 78.59  ? 315 LEU D O   1 
ATOM 4570 C CB  . LEU D 1 225 ? 131.989 103.737 151.216 1.00 78.59  ? 315 LEU D CB  1 
ATOM 4571 C CG  . LEU D 1 225 ? 132.157 103.727 152.721 1.00 78.59  ? 315 LEU D CG  1 
ATOM 4572 C CD1 . LEU D 1 225 ? 133.013 102.557 153.150 1.00 78.59  ? 315 LEU D CD1 1 
ATOM 4573 C CD2 . LEU D 1 225 ? 132.805 105.027 153.111 1.00 78.59  ? 315 LEU D CD2 1 
ATOM 4574 N N   . LYS D 1 226 ? 130.589 104.493 148.402 1.00 75.30  ? 316 LYS D N   1 
ATOM 4575 C CA  . LYS D 1 226 ? 130.684 104.902 147.012 1.00 75.30  ? 316 LYS D CA  1 
ATOM 4576 C C   . LYS D 1 226 ? 129.972 106.226 146.801 1.00 75.30  ? 316 LYS D C   1 
ATOM 4577 O O   . LYS D 1 226 ? 130.462 107.097 146.075 1.00 75.30  ? 316 LYS D O   1 
ATOM 4578 C CB  . LYS D 1 226 ? 130.112 103.826 146.100 1.00 75.30  ? 316 LYS D CB  1 
ATOM 4579 C CG  . LYS D 1 226 ? 130.444 104.052 144.641 1.00 75.30  ? 316 LYS D CG  1 
ATOM 4580 C CD  . LYS D 1 226 ? 131.938 103.979 144.404 1.00 75.30  ? 316 LYS D CD  1 
ATOM 4581 C CE  . LYS D 1 226 ? 132.466 102.607 144.753 1.00 75.30  ? 316 LYS D CE  1 
ATOM 4582 N NZ  . LYS D 1 226 ? 131.811 101.553 143.932 1.00 75.30  ? 316 LYS D NZ  1 
ATOM 4583 N N   . GLY D 1 227 ? 128.825 106.406 147.452 1.00 61.12  ? 317 GLY D N   1 
ATOM 4584 C CA  . GLY D 1 227 ? 128.047 107.611 147.241 1.00 61.12  ? 317 GLY D CA  1 
ATOM 4585 C C   . GLY D 1 227 ? 128.777 108.869 147.649 1.00 61.12  ? 317 GLY D C   1 
ATOM 4586 O O   . GLY D 1 227 ? 128.475 109.955 147.149 1.00 61.12  ? 317 GLY D O   1 
ATOM 4587 N N   . TYR D 1 228 ? 129.744 108.750 148.544 1.00 54.05  ? 318 TYR D N   1 
ATOM 4588 C CA  . TYR D 1 228 ? 130.483 109.917 148.988 1.00 54.05  ? 318 TYR D CA  1 
ATOM 4589 C C   . TYR D 1 228 ? 131.874 109.987 148.400 1.00 54.05  ? 318 TYR D C   1 
ATOM 4590 O O   . TYR D 1 228 ? 132.687 110.783 148.875 1.00 54.05  ? 318 TYR D O   1 
ATOM 4591 C CB  . TYR D 1 228 ? 130.584 109.928 150.502 1.00 54.05  ? 318 TYR D CB  1 
ATOM 4592 C CG  . TYR D 1 228 ? 129.304 110.254 151.195 1.00 54.05  ? 318 TYR D CG  1 
ATOM 4593 C CD1 . TYR D 1 228 ? 129.249 111.272 152.111 1.00 54.05  ? 318 TYR D CD1 1 
ATOM 4594 C CD2 . TYR D 1 228 ? 128.156 109.543 150.943 1.00 54.05  ? 318 TYR D CD2 1 
ATOM 4595 C CE1 . TYR D 1 228 ? 128.095 111.572 152.756 1.00 54.05  ? 318 TYR D CE1 1 
ATOM 4596 C CE2 . TYR D 1 228 ? 126.997 109.841 151.581 1.00 54.05  ? 318 TYR D CE2 1 
ATOM 4597 C CZ  . TYR D 1 228 ? 126.972 110.860 152.489 1.00 54.05  ? 318 TYR D CZ  1 
ATOM 4598 O OH  . TYR D 1 228 ? 125.815 111.181 153.146 1.00 54.05  ? 318 TYR D OH  1 
ATOM 4599 N N   . GLY D 1 229 ? 132.177 109.158 147.410 1.00 68.64  ? 319 GLY D N   1 
ATOM 4600 C CA  . GLY D 1 229 ? 133.461 109.241 146.750 1.00 68.64  ? 319 GLY D CA  1 
ATOM 4601 C C   . GLY D 1 229 ? 134.667 109.085 147.644 1.00 68.64  ? 319 GLY D C   1 
ATOM 4602 O O   . GLY D 1 229 ? 135.724 109.628 147.327 1.00 68.64  ? 319 GLY D O   1 
ATOM 4603 N N   . VAL D 1 230 ? 134.548 108.372 148.756 1.00 67.71  ? 320 VAL D N   1 
ATOM 4604 C CA  . VAL D 1 230 ? 135.690 108.173 149.637 1.00 67.71  ? 320 VAL D CA  1 
ATOM 4605 C C   . VAL D 1 230 ? 136.097 106.707 149.599 1.00 67.71  ? 320 VAL D C   1 
ATOM 4606 O O   . VAL D 1 230 ? 135.261 105.813 149.758 1.00 67.71  ? 320 VAL D O   1 
ATOM 4607 C CB  . VAL D 1 230 ? 135.369 108.631 151.061 1.00 67.71  ? 320 VAL D CB  1 
ATOM 4608 C CG1 . VAL D 1 230 ? 135.095 110.111 151.055 1.00 67.71  ? 320 VAL D CG1 1 
ATOM 4609 C CG2 . VAL D 1 230 ? 134.171 107.895 151.580 1.00 67.71  ? 320 VAL D CG2 1 
ATOM 4610 N N   . SER D 1 231 ? 137.383 106.458 149.374 1.00 84.16  ? 321 SER D N   1 
ATOM 4611 C CA  . SER D 1 231 ? 137.848 105.099 149.135 1.00 84.16  ? 321 SER D CA  1 
ATOM 4612 C C   . SER D 1 231 ? 138.142 104.387 150.445 1.00 84.16  ? 321 SER D C   1 
ATOM 4613 O O   . SER D 1 231 ? 138.646 104.991 151.396 1.00 84.16  ? 321 SER D O   1 
ATOM 4614 C CB  . SER D 1 231 ? 139.089 105.103 148.256 1.00 84.16  ? 321 SER D CB  1 
ATOM 4615 O OG  . SER D 1 231 ? 139.596 103.788 148.137 1.00 84.16  ? 321 SER D OG  1 
ATOM 4616 N N   . TYR D 1 232 ? 137.845 103.098 150.476 1.00 92.37  ? 322 TYR D N   1 
ATOM 4617 C CA  . TYR D 1 232 ? 138.041 102.248 151.633 1.00 92.37  ? 322 TYR D CA  1 
ATOM 4618 C C   . TYR D 1 232 ? 138.791 100.999 151.210 1.00 92.37  ? 322 TYR D C   1 
ATOM 4619 O O   . TYR D 1 232 ? 139.113 100.812 150.035 1.00 92.37  ? 322 TYR D O   1 
ATOM 4620 C CB  . TYR D 1 232 ? 136.709 101.847 152.251 1.00 92.37  ? 322 TYR D CB  1 
ATOM 4621 C CG  . TYR D 1 232 ? 135.909 100.950 151.348 1.00 92.37  ? 322 TYR D CG  1 
ATOM 4622 C CD1 . TYR D 1 232 ? 135.321 101.445 150.200 1.00 92.37  ? 322 TYR D CD1 1 
ATOM 4623 C CD2 . TYR D 1 232 ? 135.746 99.610  151.635 1.00 92.37  ? 322 TYR D CD2 1 
ATOM 4624 C CE1 . TYR D 1 232 ? 134.592 100.636 149.370 1.00 92.37  ? 322 TYR D CE1 1 
ATOM 4625 C CE2 . TYR D 1 232 ? 135.015 98.793  150.812 1.00 92.37  ? 322 TYR D CE2 1 
ATOM 4626 C CZ  . TYR D 1 232 ? 134.440 99.313  149.679 1.00 92.37  ? 322 TYR D CZ  1 
ATOM 4627 O OH  . TYR D 1 232 ? 133.706 98.508  148.847 1.00 92.37  ? 322 TYR D OH  1 
ATOM 4628 N N   . ASP D 1 233 ? 139.050 100.131 152.179 1.00 118.76 ? 323 ASP D N   1 
ATOM 4629 C CA  . ASP D 1 233 ? 139.703 98.861  151.910 1.00 118.76 ? 323 ASP D CA  1 
ATOM 4630 C C   . ASP D 1 233 ? 138.681 97.737  151.991 1.00 118.76 ? 323 ASP D C   1 
ATOM 4631 O O   . ASP D 1 233 ? 137.817 97.735  152.872 1.00 118.76 ? 323 ASP D O   1 
ATOM 4632 C CB  . ASP D 1 233 ? 140.845 98.623  152.894 1.00 118.76 ? 323 ASP D CB  1 
ATOM 4633 C CG  . ASP D 1 233 ? 142.047 99.490  152.599 1.00 118.76 ? 323 ASP D CG  1 
ATOM 4634 O OD1 . ASP D 1 233 ? 141.986 100.275 151.630 1.00 118.76 ? 323 ASP D OD1 1 
ATOM 4635 O OD2 . ASP D 1 233 ? 143.052 99.390  153.331 1.00 118.76 ? 323 ASP D OD2 1 
ATOM 4636 N N   . GLU D 1 234 ? 138.790 96.781  151.073 1.00 122.51 ? 324 GLU D N   1 
ATOM 4637 C CA  . GLU D 1 234 ? 137.818 95.703  150.972 1.00 122.51 ? 324 GLU D CA  1 
ATOM 4638 C C   . GLU D 1 234 ? 137.890 94.728  152.133 1.00 122.51 ? 324 GLU D C   1 
ATOM 4639 O O   . GLU D 1 234 ? 136.947 93.955  152.331 1.00 122.51 ? 324 GLU D O   1 
ATOM 4640 C CB  . GLU D 1 234 ? 138.037 94.955  149.662 1.00 122.51 ? 324 GLU D CB  1 
ATOM 4641 C CG  . GLU D 1 234 ? 137.711 95.779  148.436 1.00 122.51 ? 324 GLU D CG  1 
ATOM 4642 C CD  . GLU D 1 234 ? 138.785 96.796  148.113 1.00 122.51 ? 324 GLU D CD  1 
ATOM 4643 O OE1 . GLU D 1 234 ? 139.797 96.851  148.843 1.00 122.51 ? 324 GLU D OE1 1 
ATOM 4644 O OE2 . GLU D 1 234 ? 138.613 97.543  147.130 1.00 122.51 ? 324 GLU D OE2 1 
ATOM 4645 N N   . ASN D 1 235 ? 138.974 94.749  152.900 1.00 130.81 ? 325 ASN D N   1 
ATOM 4646 C CA  . ASN D 1 235 ? 139.162 93.796  153.980 1.00 130.81 ? 325 ASN D CA  1 
ATOM 4647 C C   . ASN D 1 235 ? 138.960 94.415  155.354 1.00 130.81 ? 325 ASN D C   1 
ATOM 4648 O O   . ASN D 1 235 ? 138.446 93.743  156.254 1.00 130.81 ? 325 ASN D O   1 
ATOM 4649 C CB  . ASN D 1 235 ? 140.571 93.201  153.903 1.00 130.81 ? 325 ASN D CB  1 
ATOM 4650 C CG  . ASN D 1 235 ? 141.119 93.192  152.492 1.00 130.81 ? 325 ASN D CG  1 
ATOM 4651 O OD1 . ASN D 1 235 ? 140.371 93.262  151.521 1.00 130.81 ? 325 ASN D OD1 1 
ATOM 4652 N ND2 . ASN D 1 235 ? 142.436 93.117  152.372 1.00 130.81 ? 325 ASN D ND2 1 
ATOM 4653 N N   . ASP D 1 236 ? 139.330 95.681  155.528 1.00 121.77 ? 326 ASP D N   1 
ATOM 4654 C CA  . ASP D 1 236 ? 139.278 96.360  156.818 1.00 121.77 ? 326 ASP D CA  1 
ATOM 4655 C C   . ASP D 1 236 ? 137.871 96.910  156.987 1.00 121.77 ? 326 ASP D C   1 
ATOM 4656 O O   . ASP D 1 236 ? 137.598 98.073  156.684 1.00 121.77 ? 326 ASP D O   1 
ATOM 4657 C CB  . ASP D 1 236 ? 140.344 97.467  156.900 1.00 121.77 ? 326 ASP D CB  1 
ATOM 4658 C CG  . ASP D 1 236 ? 140.397 98.144  158.266 1.00 121.77 ? 326 ASP D CG  1 
ATOM 4659 O OD1 . ASP D 1 236 ? 139.334 98.427  158.864 1.00 121.77 ? 326 ASP D OD1 1 
ATOM 4660 O OD2 . ASP D 1 236 ? 141.521 98.400  158.744 1.00 121.77 ? 326 ASP D OD2 1 
ATOM 4661 N N   . GLN D 1 237 ? 136.972 96.062  157.477 1.00 116.96 ? 327 GLN D N   1 
ATOM 4662 C CA  . GLN D 1 237 ? 135.660 96.546  157.870 1.00 116.96 ? 327 GLN D CA  1 
ATOM 4663 C C   . GLN D 1 237 ? 135.757 97.562  158.993 1.00 116.96 ? 327 GLN D C   1 
ATOM 4664 O O   . GLN D 1 237 ? 134.920 98.466  159.077 1.00 116.96 ? 327 GLN D O   1 
ATOM 4665 C CB  . GLN D 1 237 ? 134.792 95.372  158.301 1.00 116.96 ? 327 GLN D CB  1 
ATOM 4666 C CG  . GLN D 1 237 ? 135.097 94.108  157.539 1.00 116.96 ? 327 GLN D CG  1 
ATOM 4667 C CD  . GLN D 1 237 ? 133.935 93.149  157.531 1.00 116.96 ? 327 GLN D CD  1 
ATOM 4668 O OE1 . GLN D 1 237 ? 133.228 93.008  158.528 1.00 116.96 ? 327 GLN D OE1 1 
ATOM 4669 N NE2 . GLN D 1 237 ? 133.723 92.486  156.403 1.00 116.96 ? 327 GLN D NE2 1 
ATOM 4670 N N   . SER D 1 238 ? 136.793 97.453  159.827 1.00 121.07 ? 328 SER D N   1 
ATOM 4671 C CA  . SER D 1 238 ? 136.852 98.185  161.087 1.00 121.07 ? 328 SER D CA  1 
ATOM 4672 C C   . SER D 1 238 ? 136.799 99.691  160.896 1.00 121.07 ? 328 SER D C   1 
ATOM 4673 O O   . SER D 1 238 ? 136.436 100.413 161.828 1.00 121.07 ? 328 SER D O   1 
ATOM 4674 C CB  . SER D 1 238 ? 138.129 97.821  161.835 1.00 121.07 ? 328 SER D CB  1 
ATOM 4675 O OG  . SER D 1 238 ? 139.194 98.651  161.409 1.00 121.07 ? 328 SER D OG  1 
ATOM 4676 N N   . LEU D 1 239 ? 137.173 100.191 159.725 1.00 113.76 ? 329 LEU D N   1 
ATOM 4677 C CA  . LEU D 1 239 ? 137.249 101.637 159.583 1.00 113.76 ? 329 LEU D CA  1 
ATOM 4678 C C   . LEU D 1 239 ? 136.091 102.190 158.769 1.00 113.76 ? 329 LEU D C   1 
ATOM 4679 O O   . LEU D 1 239 ? 135.930 103.414 158.681 1.00 113.76 ? 329 LEU D O   1 
ATOM 4680 C CB  . LEU D 1 239 ? 138.586 102.023 158.968 1.00 113.76 ? 329 LEU D CB  1 
ATOM 4681 C CG  . LEU D 1 239 ? 139.782 101.720 159.872 1.00 113.76 ? 329 LEU D CG  1 
ATOM 4682 C CD1 . LEU D 1 239 ? 140.952 102.612 159.504 1.00 113.76 ? 329 LEU D CD1 1 
ATOM 4683 C CD2 . LEU D 1 239 ? 139.420 101.893 161.342 1.00 113.76 ? 329 LEU D CD2 1 
ATOM 4684 N N   . TRP D 1 240 ? 135.286 101.316 158.164 1.00 104.42 ? 330 TRP D N   1 
ATOM 4685 C CA  . TRP D 1 240 ? 134.154 101.783 157.377 1.00 104.42 ? 330 TRP D CA  1 
ATOM 4686 C C   . TRP D 1 240 ? 133.280 102.723 158.184 1.00 104.42 ? 330 TRP D C   1 
ATOM 4687 O O   . TRP D 1 240 ? 133.031 103.860 157.776 1.00 104.42 ? 330 TRP D O   1 
ATOM 4688 C CB  . TRP D 1 240 ? 133.322 100.601 156.889 1.00 104.42 ? 330 TRP D CB  1 
ATOM 4689 C CG  . TRP D 1 240 ? 134.047 99.692  155.996 1.00 104.42 ? 330 TRP D CG  1 
ATOM 4690 C CD1 . TRP D 1 240 ? 135.152 99.979  155.266 1.00 104.42 ? 330 TRP D CD1 1 
ATOM 4691 C CD2 . TRP D 1 240 ? 133.723 98.330  155.726 1.00 104.42 ? 330 TRP D CD2 1 
ATOM 4692 N NE1 . TRP D 1 240 ? 135.546 98.875  154.557 1.00 104.42 ? 330 TRP D NE1 1 
ATOM 4693 C CE2 . TRP D 1 240 ? 134.681 97.848  154.821 1.00 104.42 ? 330 TRP D CE2 1 
ATOM 4694 C CE3 . TRP D 1 240 ? 132.718 97.470  156.164 1.00 104.42 ? 330 TRP D CE3 1 
ATOM 4695 C CZ2 . TRP D 1 240 ? 134.665 96.544  154.343 1.00 104.42 ? 330 TRP D CZ2 1 
ATOM 4696 C CZ3 . TRP D 1 240 ? 132.700 96.176  155.689 1.00 104.42 ? 330 TRP D CZ3 1 
ATOM 4697 C CH2 . TRP D 1 240 ? 133.667 95.725  154.789 1.00 104.42 ? 330 TRP D CH2 1 
ATOM 4698 N N   . LYS D 1 241 ? 132.786 102.250 159.323 1.00 101.99 ? 331 LYS D N   1 
ATOM 4699 C CA  . LYS D 1 241 ? 131.807 103.020 160.072 1.00 101.99 ? 331 LYS D CA  1 
ATOM 4700 C C   . LYS D 1 241 ? 132.379 104.360 160.490 1.00 101.99 ? 331 LYS D C   1 
ATOM 4701 O O   . LYS D 1 241 ? 131.738 105.403 160.314 1.00 101.99 ? 331 LYS D O   1 
ATOM 4702 C CB  . LYS D 1 241 ? 131.351 102.222 161.285 1.00 101.99 ? 331 LYS D CB  1 
ATOM 4703 C CG  . LYS D 1 241 ? 130.708 100.899 160.936 1.00 101.99 ? 331 LYS D CG  1 
ATOM 4704 C CD  . LYS D 1 241 ? 130.057 100.279 162.152 1.00 101.99 ? 331 LYS D CD  1 
ATOM 4705 C CE  . LYS D 1 241 ? 129.175 99.106  161.784 1.00 101.99 ? 331 LYS D CE  1 
ATOM 4706 N NZ  . LYS D 1 241 ? 128.262 98.741  162.904 1.00 101.99 ? 331 LYS D NZ  1 
ATOM 4707 N N   . ARG D 1 242 ? 133.587 104.356 161.033 1.00 99.35  ? 332 ARG D N   1 
ATOM 4708 C CA  . ARG D 1 242 ? 134.171 105.617 161.441 1.00 99.35  ? 332 ARG D CA  1 
ATOM 4709 C C   . ARG D 1 242 ? 134.342 106.553 160.265 1.00 99.35  ? 332 ARG D C   1 
ATOM 4710 O O   . ARG D 1 242 ? 134.033 107.744 160.379 1.00 99.35  ? 332 ARG D O   1 
ATOM 4711 C CB  . ARG D 1 242 ? 135.512 105.389 162.132 1.00 99.35  ? 332 ARG D CB  1 
ATOM 4712 C CG  . ARG D 1 242 ? 135.396 105.240 163.633 1.00 99.35  ? 332 ARG D CG  1 
ATOM 4713 C CD  . ARG D 1 242 ? 135.133 106.575 164.300 1.00 99.35  ? 332 ARG D CD  1 
ATOM 4714 N NE  . ARG D 1 242 ? 134.588 106.405 165.641 1.00 99.35  ? 332 ARG D NE  1 
ATOM 4715 C CZ  . ARG D 1 242 ? 134.524 107.370 166.550 1.00 99.35  ? 332 ARG D CZ  1 
ATOM 4716 N NH1 . ARG D 1 242 ? 134.976 108.582 166.270 1.00 99.35  ? 332 ARG D NH1 1 
ATOM 4717 N NH2 . ARG D 1 242 ? 134.008 107.119 167.742 1.00 99.35  ? 332 ARG D NH2 1 
ATOM 4718 N N   . GLN D 1 243 ? 134.806 106.050 159.126 1.00 87.27  ? 333 GLN D N   1 
ATOM 4719 C CA  . GLN D 1 243 ? 135.085 106.962 158.031 1.00 87.27  ? 333 GLN D CA  1 
ATOM 4720 C C   . GLN D 1 243 ? 133.791 107.487 157.433 1.00 87.27  ? 333 GLN D C   1 
ATOM 4721 O O   . GLN D 1 243 ? 133.717 108.644 157.012 1.00 87.27  ? 333 GLN D O   1 
ATOM 4722 C CB  . GLN D 1 243 ? 135.958 106.277 156.987 1.00 87.27  ? 333 GLN D CB  1 
ATOM 4723 C CG  . GLN D 1 243 ? 136.697 107.260 156.105 1.00 87.27  ? 333 GLN D CG  1 
ATOM 4724 C CD  . GLN D 1 243 ? 137.965 106.683 155.520 1.00 87.27  ? 333 GLN D CD  1 
ATOM 4725 O OE1 . GLN D 1 243 ? 138.302 105.526 155.759 1.00 87.27  ? 333 GLN D OE1 1 
ATOM 4726 N NE2 . GLN D 1 243 ? 138.683 107.492 154.754 1.00 87.27  ? 333 GLN D NE2 1 
ATOM 4727 N N   . LEU D 1 244 ? 132.742 106.674 157.445 1.00 72.63  ? 334 LEU D N   1 
ATOM 4728 C CA  . LEU D 1 244 ? 131.450 107.157 156.982 1.00 72.63  ? 334 LEU D CA  1 
ATOM 4729 C C   . LEU D 1 244 ? 130.931 108.249 157.894 1.00 72.63  ? 334 LEU D C   1 
ATOM 4730 O O   . LEU D 1 244 ? 130.434 109.282 157.429 1.00 72.63  ? 334 LEU D O   1 
ATOM 4731 C CB  . LEU D 1 244 ? 130.457 106.010 156.921 1.00 72.63  ? 334 LEU D CB  1 
ATOM 4732 C CG  . LEU D 1 244 ? 129.049 106.470 156.615 1.00 72.63  ? 334 LEU D CG  1 
ATOM 4733 C CD1 . LEU D 1 244 ? 129.068 107.157 155.290 1.00 72.63  ? 334 LEU D CD1 1 
ATOM 4734 C CD2 . LEU D 1 244 ? 128.144 105.277 156.565 1.00 72.63  ? 334 LEU D CD2 1 
ATOM 4735 N N   . ALA D 1 245 ? 131.030 108.031 159.201 1.00 73.83  ? 335 ALA D N   1 
ATOM 4736 C CA  . ALA D 1 245 ? 130.688 109.083 160.142 1.00 73.83  ? 335 ALA D CA  1 
ATOM 4737 C C   . ALA D 1 245 ? 131.427 110.362 159.795 1.00 73.83  ? 335 ALA D C   1 
ATOM 4738 O O   . ALA D 1 245 ? 130.811 111.407 159.561 1.00 73.83  ? 335 ALA D O   1 
ATOM 4739 C CB  . ALA D 1 245 ? 131.018 108.639 161.563 1.00 73.83  ? 335 ALA D CB  1 
ATOM 4740 N N   . LYS D 1 246 ? 132.754 110.282 159.713 1.00 77.80  ? 336 LYS D N   1 
ATOM 4741 C CA  . LYS D 1 246 ? 133.545 111.461 159.397 1.00 77.80  ? 336 LYS D CA  1 
ATOM 4742 C C   . LYS D 1 246 ? 133.193 112.036 158.040 1.00 77.80  ? 336 LYS D C   1 
ATOM 4743 O O   . LYS D 1 246 ? 133.508 113.197 157.766 1.00 77.80  ? 336 LYS D O   1 
ATOM 4744 C CB  . LYS D 1 246 ? 135.032 111.134 159.446 1.00 77.80  ? 336 LYS D CB  1 
ATOM 4745 C CG  . LYS D 1 246 ? 135.574 110.977 160.845 1.00 77.80  ? 336 LYS D CG  1 
ATOM 4746 C CD  . LYS D 1 246 ? 137.056 111.265 160.884 1.00 77.80  ? 336 LYS D CD  1 
ATOM 4747 C CE  . LYS D 1 246 ? 137.638 110.917 162.237 1.00 77.80  ? 336 LYS D CE  1 
ATOM 4748 N NZ  . LYS D 1 246 ? 138.978 111.530 162.433 1.00 77.80  ? 336 LYS D NZ  1 
ATOM 4749 N N   . ALA D 1 247 ? 132.557 111.253 157.182 1.00 61.96  ? 337 ALA D N   1 
ATOM 4750 C CA  . ALA D 1 247 ? 132.142 111.802 155.905 1.00 61.96  ? 337 ALA D CA  1 
ATOM 4751 C C   . ALA D 1 247 ? 130.866 112.615 156.041 1.00 61.96  ? 337 ALA D C   1 
ATOM 4752 O O   . ALA D 1 247 ? 130.776 113.719 155.505 1.00 61.96  ? 337 ALA D O   1 
ATOM 4753 C CB  . ALA D 1 247 ? 131.965 110.682 154.890 1.00 61.96  ? 337 ALA D CB  1 
ATOM 4754 N N   . VAL D 1 248 ? 129.858 112.092 156.738 1.00 63.87  ? 338 VAL D N   1 
ATOM 4755 C CA  . VAL D 1 248 ? 128.624 112.861 156.863 1.00 63.87  ? 338 VAL D CA  1 
ATOM 4756 C C   . VAL D 1 248 ? 128.743 113.988 157.868 1.00 63.87  ? 338 VAL D C   1 
ATOM 4757 O O   . VAL D 1 248 ? 128.125 115.041 157.669 1.00 63.87  ? 338 VAL D O   1 
ATOM 4758 C CB  . VAL D 1 248 ? 127.410 112.012 157.259 1.00 63.87  ? 338 VAL D CB  1 
ATOM 4759 C CG1 . VAL D 1 248 ? 127.052 111.079 156.140 1.00 63.87  ? 338 VAL D CG1 1 
ATOM 4760 C CG2 . VAL D 1 248 ? 127.693 111.255 158.539 1.00 63.87  ? 338 VAL D CG2 1 
ATOM 4761 N N   . GLY D 1 249 ? 129.502 113.805 158.931 1.00 71.84  ? 339 GLY D N   1 
ATOM 4762 C CA  . GLY D 1 249 ? 129.714 114.843 159.906 1.00 71.84  ? 339 GLY D CA  1 
ATOM 4763 C C   . GLY D 1 249 ? 129.470 114.477 161.347 1.00 71.84  ? 339 GLY D C   1 
ATOM 4764 O O   . GLY D 1 249 ? 129.528 115.366 162.203 1.00 71.84  ? 339 GLY D O   1 
ATOM 4765 N N   . LEU D 1 250 ? 129.239 113.210 161.652 1.00 86.26  ? 340 LEU D N   1 
ATOM 4766 C CA  . LEU D 1 250 ? 128.997 112.808 163.031 1.00 86.26  ? 340 LEU D CA  1 
ATOM 4767 C C   . LEU D 1 250 ? 130.300 113.005 163.786 1.00 86.26  ? 340 LEU D C   1 
ATOM 4768 O O   . LEU D 1 250 ? 131.205 112.174 163.744 1.00 86.26  ? 340 LEU D O   1 
ATOM 4769 C CB  . LEU D 1 250 ? 128.518 111.370 163.093 1.00 86.26  ? 340 LEU D CB  1 
ATOM 4770 C CG  . LEU D 1 250 ? 127.022 111.256 162.852 1.00 86.26  ? 340 LEU D CG  1 
ATOM 4771 C CD1 . LEU D 1 250 ? 126.561 109.844 163.101 1.00 86.26  ? 340 LEU D CD1 1 
ATOM 4772 C CD2 . LEU D 1 250 ? 126.296 112.217 163.752 1.00 86.26  ? 340 LEU D CD2 1 
ATOM 4773 N N   . THR D 1 251 ? 130.399 114.130 164.485 1.00 89.43  ? 341 THR D N   1 
ATOM 4774 C CA  . THR D 1 251 ? 131.686 114.600 164.970 1.00 89.43  ? 341 THR D CA  1 
ATOM 4775 C C   . THR D 1 251 ? 131.715 114.880 166.468 1.00 89.43  ? 341 THR D C   1 
ATOM 4776 O O   . THR D 1 251 ? 132.800 115.084 167.018 1.00 89.43  ? 341 THR D O   1 
ATOM 4777 C CB  . THR D 1 251 ? 132.078 115.867 164.196 1.00 89.43  ? 341 THR D CB  1 
ATOM 4778 O OG1 . THR D 1 251 ? 131.929 115.618 162.796 1.00 89.43  ? 341 THR D OG1 1 
ATOM 4779 C CG2 . THR D 1 251 ? 133.529 116.227 164.439 1.00 89.43  ? 341 THR D CG2 1 
ATOM 4780 N N   . ALA D 1 252 ? 130.574 114.877 167.150 1.00 105.88 ? 342 ALA D N   1 
ATOM 4781 C CA  . ALA D 1 252 ? 130.521 115.325 168.532 1.00 105.88 ? 342 ALA D CA  1 
ATOM 4782 C C   . ALA D 1 252 ? 131.382 114.448 169.437 1.00 105.88 ? 342 ALA D C   1 
ATOM 4783 O O   . ALA D 1 252 ? 131.860 113.378 169.054 1.00 105.88 ? 342 ALA D O   1 
ATOM 4784 C CB  . ALA D 1 252 ? 129.084 115.326 169.042 1.00 105.88 ? 342 ALA D CB  1 
ATOM 4785 N N   . ALA D 1 253 ? 131.577 114.930 170.664 1.00 114.30 ? 343 ALA D N   1 
ATOM 4786 C CA  . ALA D 1 253 ? 132.347 114.172 171.641 1.00 114.30 ? 343 ALA D CA  1 
ATOM 4787 C C   . ALA D 1 253 ? 131.739 112.800 171.881 1.00 114.30 ? 343 ALA D C   1 
ATOM 4788 O O   . ALA D 1 253 ? 132.461 111.796 171.929 1.00 114.30 ? 343 ALA D O   1 
ATOM 4789 C CB  . ALA D 1 253 ? 132.439 114.952 172.952 1.00 114.30 ? 343 ALA D CB  1 
ATOM 4790 N N   . TYR D 1 254 ? 130.418 112.732 172.034 1.00 120.14 ? 344 TYR D N   1 
ATOM 4791 C CA  . TYR D 1 254 ? 129.777 111.431 172.130 1.00 120.14 ? 344 TYR D CA  1 
ATOM 4792 C C   . TYR D 1 254 ? 129.994 110.636 170.852 1.00 120.14 ? 344 TYR D C   1 
ATOM 4793 O O   . TYR D 1 254 ? 130.138 109.410 170.888 1.00 120.14 ? 344 TYR D O   1 
ATOM 4794 C CB  . TYR D 1 254 ? 128.287 111.575 172.419 1.00 120.14 ? 344 TYR D CB  1 
ATOM 4795 C CG  . TYR D 1 254 ? 127.540 110.303 172.117 1.00 120.14 ? 344 TYR D CG  1 
ATOM 4796 C CD1 . TYR D 1 254 ? 126.723 110.200 171.003 1.00 120.14 ? 344 TYR D CD1 1 
ATOM 4797 C CD2 . TYR D 1 254 ? 127.687 109.188 172.926 1.00 120.14 ? 344 TYR D CD2 1 
ATOM 4798 C CE1 . TYR D 1 254 ? 126.051 109.030 170.719 1.00 120.14 ? 344 TYR D CE1 1 
ATOM 4799 C CE2 . TYR D 1 254 ? 127.021 108.015 172.649 1.00 120.14 ? 344 TYR D CE2 1 
ATOM 4800 C CZ  . TYR D 1 254 ? 126.205 107.941 171.545 1.00 120.14 ? 344 TYR D CZ  1 
ATOM 4801 O OH  . TYR D 1 254 ? 125.538 106.772 171.268 1.00 120.14 ? 344 TYR D OH  1 
ATOM 4802 N N   . ASP D 1 255 ? 130.021 111.325 169.710 1.00 109.46 ? 345 ASP D N   1 
ATOM 4803 C CA  . ASP D 1 255 ? 130.269 110.641 168.448 1.00 109.46 ? 345 ASP D CA  1 
ATOM 4804 C C   . ASP D 1 255 ? 131.641 109.987 168.447 1.00 109.46 ? 345 ASP D C   1 
ATOM 4805 O O   . ASP D 1 255 ? 131.864 108.987 167.756 1.00 109.46 ? 345 ASP D O   1 
ATOM 4806 C CB  . ASP D 1 255 ? 130.151 111.621 167.287 1.00 109.46 ? 345 ASP D CB  1 
ATOM 4807 C CG  . ASP D 1 255 ? 128.784 112.245 167.198 1.00 109.46 ? 345 ASP D CG  1 
ATOM 4808 O OD1 . ASP D 1 255 ? 127.817 111.628 167.691 1.00 109.46 ? 345 ASP D OD1 1 
ATOM 4809 O OD2 . ASP D 1 255 ? 128.675 113.346 166.622 1.00 109.46 ? 345 ASP D OD2 1 
ATOM 4810 N N   . ALA D 1 256 ? 132.579 110.539 169.215 1.00 117.23 ? 346 ALA D N   1 
ATOM 4811 C CA  . ALA D 1 256 ? 133.871 109.889 169.365 1.00 117.23 ? 346 ALA D CA  1 
ATOM 4812 C C   . ALA D 1 256 ? 133.829 108.769 170.393 1.00 117.23 ? 346 ALA D C   1 
ATOM 4813 O O   . ALA D 1 256 ? 134.405 107.704 170.153 1.00 117.23 ? 346 ALA D O   1 
ATOM 4814 C CB  . ALA D 1 256 ? 134.932 110.911 169.743 1.00 50.00  ? 346 ALA D CB  1 
ATOM 4815 N N   . SER D 1 257 ? 133.144 108.977 171.515 1.00 122.35 ? 347 SER D N   1 
ATOM 4816 C CA  . SER D 1 257 ? 133.170 108.003 172.597 1.00 122.35 ? 347 SER D CA  1 
ATOM 4817 C C   . SER D 1 257 ? 132.362 106.747 172.301 1.00 122.35 ? 347 SER D C   1 
ATOM 4818 O O   . SER D 1 257 ? 132.597 105.717 172.939 1.00 122.35 ? 347 SER D O   1 
ATOM 4819 C CB  . SER D 1 257 ? 132.655 108.639 173.886 1.00 122.35 ? 347 SER D CB  1 
ATOM 4820 O OG  . SER D 1 257 ? 131.470 109.370 173.646 1.00 122.35 ? 347 SER D OG  1 
ATOM 4821 N N   . TYR D 1 258 ? 131.425 106.802 171.364 1.00 126.75 ? 348 TYR D N   1 
ATOM 4822 C CA  . TYR D 1 258 ? 130.613 105.635 171.051 1.00 126.75 ? 348 TYR D CA  1 
ATOM 4823 C C   . TYR D 1 258 ? 131.464 104.590 170.347 1.00 126.75 ? 348 TYR D C   1 
ATOM 4824 O O   . TYR D 1 258 ? 132.399 104.931 169.615 1.00 126.75 ? 348 TYR D O   1 
ATOM 4825 C CB  . TYR D 1 258 ? 129.430 106.039 170.182 1.00 126.75 ? 348 TYR D CB  1 
ATOM 4826 C CG  . TYR D 1 258 ? 128.601 104.884 169.678 1.00 126.75 ? 348 TYR D CG  1 
ATOM 4827 C CD1 . TYR D 1 258 ? 128.897 104.265 168.472 1.00 126.75 ? 348 TYR D CD1 1 
ATOM 4828 C CD2 . TYR D 1 258 ? 127.519 104.418 170.405 1.00 126.75 ? 348 TYR D CD2 1 
ATOM 4829 C CE1 . TYR D 1 258 ? 128.137 103.223 168.006 1.00 126.75 ? 348 TYR D CE1 1 
ATOM 4830 C CE2 . TYR D 1 258 ? 126.757 103.370 169.949 1.00 126.75 ? 348 TYR D CE2 1 
ATOM 4831 C CZ  . TYR D 1 258 ? 127.071 102.775 168.750 1.00 126.75 ? 348 TYR D CZ  1 
ATOM 4832 O OH  . TYR D 1 258 ? 126.310 101.728 168.290 1.00 126.75 ? 348 TYR D OH  1 
ATOM 4833 N N   . THR D 1 259 ? 131.147 103.318 170.570 1.00 127.14 ? 349 THR D N   1 
ATOM 4834 C CA  . THR D 1 259 ? 131.876 102.219 169.942 1.00 127.14 ? 349 THR D CA  1 
ATOM 4835 C C   . THR D 1 259 ? 130.970 101.539 168.925 1.00 127.14 ? 349 THR D C   1 
ATOM 4836 O O   . THR D 1 259 ? 129.840 101.150 169.220 1.00 127.14 ? 349 THR D O   1 
ATOM 4837 C CB  . THR D 1 259 ? 132.389 101.240 170.992 1.00 127.14 ? 349 THR D CB  1 
ATOM 4838 O OG1 . THR D 1 259 ? 133.064 100.156 170.341 1.00 127.14 ? 349 THR D OG1 1 
ATOM 4839 C CG2 . THR D 1 259 ? 131.252 100.703 171.854 1.00 127.14 ? 349 THR D CG2 1 
ATOM 4840 N N   . PHE D 1 260 ? 131.477 101.401 167.705 1.00 123.73 ? 350 PHE D N   1 
ATOM 4841 C CA  . PHE D 1 260 ? 130.723 100.736 166.654 1.00 123.73 ? 350 PHE D CA  1 
ATOM 4842 C C   . PHE D 1 260 ? 130.580 99.251  166.952 1.00 123.73 ? 350 PHE D C   1 
ATOM 4843 O O   . PHE D 1 260 ? 131.417 98.651  167.630 1.00 123.73 ? 350 PHE D O   1 
ATOM 4844 C CB  . PHE D 1 260 ? 131.415 100.929 165.309 1.00 123.73 ? 350 PHE D CB  1 
ATOM 4845 C CG  . PHE D 1 260 ? 131.231 102.296 164.723 1.00 123.73 ? 350 PHE D CG  1 
ATOM 4846 C CD1 . PHE D 1 260 ? 129.966 102.793 164.476 1.00 123.73 ? 350 PHE D CD1 1 
ATOM 4847 C CD2 . PHE D 1 260 ? 132.326 103.085 164.419 1.00 123.73 ? 350 PHE D CD2 1 
ATOM 4848 C CE1 . PHE D 1 260 ? 129.800 104.049 163.935 1.00 123.73 ? 350 PHE D CE1 1 
ATOM 4849 C CE2 . PHE D 1 260 ? 132.160 104.340 163.880 1.00 123.73 ? 350 PHE D CE2 1 
ATOM 4850 C CZ  . PHE D 1 260 ? 130.900 104.821 163.636 1.00 123.73 ? 350 PHE D CZ  1 
ATOM 4851 N N   . SER D 1 261 ? 129.507 98.661  166.445 1.00 123.63 ? 351 SER D N   1 
ATOM 4852 C CA  . SER D 1 261 ? 129.308 97.232  166.604 1.00 123.63 ? 351 SER D CA  1 
ATOM 4853 C C   . SER D 1 261 ? 129.820 96.497  165.370 1.00 123.63 ? 351 SER D C   1 
ATOM 4854 O O   . SER D 1 261 ? 129.921 97.089  164.291 1.00 123.63 ? 351 SER D O   1 
ATOM 4855 C CB  . SER D 1 261 ? 127.830 96.920  166.824 1.00 123.63 ? 351 SER D CB  1 
ATOM 4856 O OG  . SER D 1 261 ? 127.022 97.608  165.887 1.00 123.63 ? 351 SER D OG  1 
ATOM 4857 N N   . PRO D 1 262 ? 130.163 95.216  165.490 1.00 128.78 ? 352 PRO D N   1 
ATOM 4858 C CA  . PRO D 1 262 ? 130.563 94.444  164.311 1.00 128.78 ? 352 PRO D CA  1 
ATOM 4859 C C   . PRO D 1 262 ? 129.350 93.975  163.523 1.00 128.78 ? 352 PRO D C   1 
ATOM 4860 O O   . PRO D 1 262 ? 128.210 94.011  163.988 1.00 128.78 ? 352 PRO D O   1 
ATOM 4861 C CB  . PRO D 1 262 ? 131.332 93.266  164.906 1.00 128.78 ? 352 PRO D CB  1 
ATOM 4862 C CG  . PRO D 1 262 ? 130.700 93.069  166.240 1.00 128.78 ? 352 PRO D CG  1 
ATOM 4863 C CD  . PRO D 1 262 ? 130.320 94.441  166.734 1.00 128.78 ? 352 PRO D CD  1 
ATOM 4864 N N   . PHE D 1 263 ? 129.612 93.520  162.302 1.00 134.59 ? 353 PHE D N   1 
ATOM 4865 C CA  . PHE D 1 263 ? 128.540 93.053  161.441 1.00 134.59 ? 353 PHE D CA  1 
ATOM 4866 C C   . PHE D 1 263 ? 128.094 91.651  161.833 1.00 134.59 ? 353 PHE D C   1 
ATOM 4867 O O   . PHE D 1 263 ? 128.668 91.007  162.714 1.00 134.59 ? 353 PHE D O   1 
ATOM 4868 C CB  . PHE D 1 263 ? 128.980 93.059  159.982 1.00 134.59 ? 353 PHE D CB  1 
ATOM 4869 C CG  . PHE D 1 263 ? 129.143 94.427  159.417 1.00 134.59 ? 353 PHE D CG  1 
ATOM 4870 C CD1 . PHE D 1 263 ? 128.094 95.325  159.449 1.00 134.59 ? 353 PHE D CD1 1 
ATOM 4871 C CD2 . PHE D 1 263 ? 130.345 94.821  158.860 1.00 134.59 ? 353 PHE D CD2 1 
ATOM 4872 C CE1 . PHE D 1 263 ? 128.239 96.589  158.934 1.00 134.59 ? 353 PHE D CE1 1 
ATOM 4873 C CE2 . PHE D 1 263 ? 130.494 96.084  158.342 1.00 134.59 ? 353 PHE D CE2 1 
ATOM 4874 C CZ  . PHE D 1 263 ? 129.441 96.971  158.380 1.00 134.59 ? 353 PHE D CZ  1 
ATOM 4875 N N   . SER D 1 264 ? 127.053 91.181  161.156 1.00 150.60 ? 354 SER D N   1 
ATOM 4876 C CA  . SER D 1 264 ? 126.507 89.853  161.404 1.00 150.60 ? 354 SER D CA  1 
ATOM 4877 C C   . SER D 1 264 ? 127.363 88.772  160.753 1.00 150.60 ? 354 SER D C   1 
ATOM 4878 O O   . SER D 1 264 ? 126.844 87.761  160.278 1.00 150.60 ? 354 SER D O   1 
ATOM 4879 C CB  . SER D 1 264 ? 125.071 89.762  160.887 1.00 150.60 ? 354 SER D CB  1 
ATOM 4880 O OG  . SER D 1 264 ? 125.046 89.370  159.525 1.00 150.60 ? 354 SER D OG  1 
# 
