data_9J66
# 
_entry.id   9J66 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9J66         pdb_00009j66 10.2210/pdb9j66/pdb 
WWPDB D_1300047054 ?            ?                   
EMDB  EMD-61167    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9J66 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Cryo-EM structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment CAV-C65 (local refinement)
;
_pdbx_database_related.db_id          EMD-61167 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              gongpeng@wh.iov.cn 
_pdbx_contact_author.name_first         Peng 
_pdbx_contact_author.name_last          Gong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8264-7523 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Jing, X.' 1 0000-0003-4193-2210 
'Chen, Y.' 2 0000-0002-4659-1550 
'Gong, P.' 3 0000-0002-8264-7523 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   NE 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Antiviral Res.' 
_citation.journal_id_ASTM           ARSRDR 
_citation.journal_id_CSD            1136 
_citation.journal_id_ISSN           0166-3542 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            235 
_citation.language                  ? 
_citation.page_first                106082 
_citation.page_last                 106082 
_citation.title                     
'IgA class switching enhances neutralizing potency against SARS-CoV-2 by increased antibody hinge flexibility.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.antiviral.2025.106082 
_citation.pdbx_database_id_PubMed   39828085 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xu, M.'     1  ? 
primary 'Zhang, Z.'  2  ? 
primary 'Sun, Y.'    3  ? 
primary 'Mai, H.'    4  ? 
primary 'Liu, S.'    5  ? 
primary 'Liu, S.'    6  ? 
primary 'Lv, K.'     7  ? 
primary 'Yu, F.'     8  ? 
primary 'Wang, Y.'   9  ? 
primary 'Yue, X.'    10 ? 
primary 'Zhang, J.'  11 ? 
primary 'Cai, X.'    12 ? 
primary 'Zhao, R.'   13 ? 
primary 'Lu, H.'     14 ? 
primary 'Liu, L.'    15 ? 
primary 'Luo, H.'    16 ? 
primary 'Zhao, H.'   17 ? 
primary 'Wang, Y.'   18 ? 
primary 'Gong, P.'   19 ? 
primary 'Chen, S.'   20 ? 
primary 'Jing, X.'   21 ? 
primary 'Zhao, J.'   22 ? 
primary 'Chen, Y.Q.' 23 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'CAV-C65 Heavy chain' 24463.514 1 ? ? ? ? 
2 polymer man 'CAV-C65 Light chain' 23177.666 1 ? ? ? ? 
3 polymer man 'Spike protein S1'    21873.496 2 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPIFGIANYAQKFQGRVTITADKSTSTAY
MELSSLRSEDTAVYYCARTPLEMATEEGYFDYWGQGTLVTVSSASVRSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCSG
;
;QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPIFGIANYAQKFQGRVTITADKSTSTAY
MELSSLRSEDTAVYYCARTPLEMATEEGYFDYWGQGTLVTVSSASVRSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCSG
;
B   ? 
2 'polypeptide(L)' no no 
;DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQTPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP
EDFATYYCQQANSFPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQTPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP
EDFATYYCQQANSFPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
C   ? 
3 'polypeptide(L)' no no 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
;
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
;
A,D ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLN n 
1 7   SER n 
1 8   GLY n 
1 9   ALA n 
1 10  GLU n 
1 11  VAL n 
1 12  LYS n 
1 13  LYS n 
1 14  PRO n 
1 15  GLY n 
1 16  SER n 
1 17  SER n 
1 18  VAL n 
1 19  LYS n 
1 20  VAL n 
1 21  SER n 
1 22  CYS n 
1 23  LYS n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  GLY n 
1 28  THR n 
1 29  PHE n 
1 30  SER n 
1 31  SER n 
1 32  TYR n 
1 33  THR n 
1 34  ILE n 
1 35  SER n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  GLN n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  MET n 
1 49  GLY n 
1 50  ARG n 
1 51  ILE n 
1 52  ILE n 
1 53  PRO n 
1 54  ILE n 
1 55  PHE n 
1 56  GLY n 
1 57  ILE n 
1 58  ALA n 
1 59  ASN n 
1 60  TYR n 
1 61  ALA n 
1 62  GLN n 
1 63  LYS n 
1 64  PHE n 
1 65  GLN n 
1 66  GLY n 
1 67  ARG n 
1 68  VAL n 
1 69  THR n 
1 70  ILE n 
1 71  THR n 
1 72  ALA n 
1 73  ASP n 
1 74  LYS n 
1 75  SER n 
1 76  THR n 
1 77  SER n 
1 78  THR n 
1 79  ALA n 
1 80  TYR n 
1 81  MET n 
1 82  GLU n 
1 83  LEU n 
1 84  SER n 
1 85  SER n 
1 86  LEU n 
1 87  ARG n 
1 88  SER n 
1 89  GLU n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  VAL n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  ARG n 
1 99  THR n 
1 100 PRO n 
1 101 LEU n 
1 102 GLU n 
1 103 MET n 
1 104 ALA n 
1 105 THR n 
1 106 GLU n 
1 107 GLU n 
1 108 GLY n 
1 109 TYR n 
1 110 PHE n 
1 111 ASP n 
1 112 TYR n 
1 113 TRP n 
1 114 GLY n 
1 115 GLN n 
1 116 GLY n 
1 117 THR n 
1 118 LEU n 
1 119 VAL n 
1 120 THR n 
1 121 VAL n 
1 122 SER n 
1 123 SER n 
1 124 ALA n 
1 125 SER n 
1 126 VAL n 
1 127 ARG n 
1 128 SER n 
1 129 THR n 
1 130 LYS n 
1 131 GLY n 
1 132 PRO n 
1 133 SER n 
1 134 VAL n 
1 135 PHE n 
1 136 PRO n 
1 137 LEU n 
1 138 ALA n 
1 139 PRO n 
1 140 SER n 
1 141 SER n 
1 142 LYS n 
1 143 SER n 
1 144 THR n 
1 145 SER n 
1 146 GLY n 
1 147 GLY n 
1 148 THR n 
1 149 ALA n 
1 150 ALA n 
1 151 LEU n 
1 152 GLY n 
1 153 CYS n 
1 154 LEU n 
1 155 VAL n 
1 156 LYS n 
1 157 ASP n 
1 158 TYR n 
1 159 PHE n 
1 160 PRO n 
1 161 GLU n 
1 162 PRO n 
1 163 VAL n 
1 164 THR n 
1 165 VAL n 
1 166 SER n 
1 167 TRP n 
1 168 ASN n 
1 169 SER n 
1 170 GLY n 
1 171 ALA n 
1 172 LEU n 
1 173 THR n 
1 174 SER n 
1 175 GLY n 
1 176 VAL n 
1 177 HIS n 
1 178 THR n 
1 179 PHE n 
1 180 PRO n 
1 181 ALA n 
1 182 VAL n 
1 183 LEU n 
1 184 GLN n 
1 185 SER n 
1 186 SER n 
1 187 GLY n 
1 188 LEU n 
1 189 TYR n 
1 190 SER n 
1 191 LEU n 
1 192 SER n 
1 193 SER n 
1 194 VAL n 
1 195 VAL n 
1 196 THR n 
1 197 VAL n 
1 198 PRO n 
1 199 SER n 
1 200 SER n 
1 201 SER n 
1 202 LEU n 
1 203 GLY n 
1 204 THR n 
1 205 GLN n 
1 206 THR n 
1 207 TYR n 
1 208 ILE n 
1 209 CYS n 
1 210 ASN n 
1 211 VAL n 
1 212 ASN n 
1 213 HIS n 
1 214 LYS n 
1 215 PRO n 
1 216 SER n 
1 217 ASN n 
1 218 THR n 
1 219 LYS n 
1 220 VAL n 
1 221 ASP n 
1 222 LYS n 
1 223 LYS n 
1 224 VAL n 
1 225 GLU n 
1 226 PRO n 
1 227 LYS n 
1 228 SER n 
1 229 CYS n 
1 230 SER n 
1 231 GLY n 
2 1   ASP n 
2 2   ILE n 
2 3   GLN n 
2 4   MET n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   SER n 
2 10  SER n 
2 11  VAL n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  VAL n 
2 16  GLY n 
2 17  ASP n 
2 18  ARG n 
2 19  VAL n 
2 20  THR n 
2 21  ILE n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  GLY n 
2 29  ILE n 
2 30  SER n 
2 31  SER n 
2 32  TRP n 
2 33  LEU n 
2 34  ALA n 
2 35  TRP n 
2 36  TYR n 
2 37  GLN n 
2 38  GLN n 
2 39  THR n 
2 40  PRO n 
2 41  GLY n 
2 42  LYS n 
2 43  ALA n 
2 44  PRO n 
2 45  LYS n 
2 46  LEU n 
2 47  LEU n 
2 48  ILE n 
2 49  TYR n 
2 50  ALA n 
2 51  ALA n 
2 52  SER n 
2 53  SER n 
2 54  LEU n 
2 55  GLN n 
2 56  SER n 
2 57  GLY n 
2 58  VAL n 
2 59  PRO n 
2 60  SER n 
2 61  ARG n 
2 62  PHE n 
2 63  SER n 
2 64  GLY n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  THR n 
2 70  ASP n 
2 71  PHE n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  ILE n 
2 76  SER n 
2 77  SER n 
2 78  LEU n 
2 79  GLN n 
2 80  PRO n 
2 81  GLU n 
2 82  ASP n 
2 83  PHE n 
2 84  ALA n 
2 85  THR n 
2 86  TYR n 
2 87  TYR n 
2 88  CYS n 
2 89  GLN n 
2 90  GLN n 
2 91  ALA n 
2 92  ASN n 
2 93  SER n 
2 94  PHE n 
2 95  PRO n 
2 96  PHE n 
2 97  THR n 
2 98  PHE n 
2 99  GLY n 
2 100 PRO n 
2 101 GLY n 
2 102 THR n 
2 103 LYS n 
2 104 VAL n 
2 105 ASP n 
2 106 ILE n 
2 107 LYS n 
2 108 ARG n 
2 109 THR n 
2 110 VAL n 
2 111 ALA n 
2 112 ALA n 
2 113 PRO n 
2 114 SER n 
2 115 VAL n 
2 116 PHE n 
2 117 ILE n 
2 118 PHE n 
2 119 PRO n 
2 120 PRO n 
2 121 SER n 
2 122 ASP n 
2 123 GLU n 
2 124 GLN n 
2 125 LEU n 
2 126 LYS n 
2 127 SER n 
2 128 GLY n 
2 129 THR n 
2 130 ALA n 
2 131 SER n 
2 132 VAL n 
2 133 VAL n 
2 134 CYS n 
2 135 LEU n 
2 136 LEU n 
2 137 ASN n 
2 138 ASN n 
2 139 PHE n 
2 140 TYR n 
2 141 PRO n 
2 142 ARG n 
2 143 GLU n 
2 144 ALA n 
2 145 LYS n 
2 146 VAL n 
2 147 GLN n 
2 148 TRP n 
2 149 LYS n 
2 150 VAL n 
2 151 ASP n 
2 152 ASN n 
2 153 ALA n 
2 154 LEU n 
2 155 GLN n 
2 156 SER n 
2 157 GLY n 
2 158 ASN n 
2 159 SER n 
2 160 GLN n 
2 161 GLU n 
2 162 SER n 
2 163 VAL n 
2 164 THR n 
2 165 GLU n 
2 166 GLN n 
2 167 ASP n 
2 168 SER n 
2 169 LYS n 
2 170 ASP n 
2 171 SER n 
2 172 THR n 
2 173 TYR n 
2 174 SER n 
2 175 LEU n 
2 176 SER n 
2 177 SER n 
2 178 THR n 
2 179 LEU n 
2 180 THR n 
2 181 LEU n 
2 182 SER n 
2 183 LYS n 
2 184 ALA n 
2 185 ASP n 
2 186 TYR n 
2 187 GLU n 
2 188 LYS n 
2 189 HIS n 
2 190 LYS n 
2 191 VAL n 
2 192 TYR n 
2 193 ALA n 
2 194 CYS n 
2 195 GLU n 
2 196 VAL n 
2 197 THR n 
2 198 HIS n 
2 199 GLN n 
2 200 GLY n 
2 201 LEU n 
2 202 SER n 
2 203 SER n 
2 204 PRO n 
2 205 VAL n 
2 206 THR n 
2 207 LYS n 
2 208 SER n 
2 209 PHE n 
2 210 ASN n 
2 211 ARG n 
2 212 GLY n 
2 213 GLU n 
2 214 CYS n 
3 1   THR n 
3 2   ASN n 
3 3   LEU n 
3 4   CYS n 
3 5   PRO n 
3 6   PHE n 
3 7   GLY n 
3 8   GLU n 
3 9   VAL n 
3 10  PHE n 
3 11  ASN n 
3 12  ALA n 
3 13  THR n 
3 14  ARG n 
3 15  PHE n 
3 16  ALA n 
3 17  SER n 
3 18  VAL n 
3 19  TYR n 
3 20  ALA n 
3 21  TRP n 
3 22  ASN n 
3 23  ARG n 
3 24  LYS n 
3 25  ARG n 
3 26  ILE n 
3 27  SER n 
3 28  ASN n 
3 29  CYS n 
3 30  VAL n 
3 31  ALA n 
3 32  ASP n 
3 33  TYR n 
3 34  SER n 
3 35  VAL n 
3 36  LEU n 
3 37  TYR n 
3 38  ASN n 
3 39  SER n 
3 40  ALA n 
3 41  SER n 
3 42  PHE n 
3 43  SER n 
3 44  THR n 
3 45  PHE n 
3 46  LYS n 
3 47  CYS n 
3 48  TYR n 
3 49  GLY n 
3 50  VAL n 
3 51  SER n 
3 52  PRO n 
3 53  THR n 
3 54  LYS n 
3 55  LEU n 
3 56  ASN n 
3 57  ASP n 
3 58  LEU n 
3 59  CYS n 
3 60  PHE n 
3 61  THR n 
3 62  ASN n 
3 63  VAL n 
3 64  TYR n 
3 65  ALA n 
3 66  ASP n 
3 67  SER n 
3 68  PHE n 
3 69  VAL n 
3 70  ILE n 
3 71  ARG n 
3 72  GLY n 
3 73  ASP n 
3 74  GLU n 
3 75  VAL n 
3 76  ARG n 
3 77  GLN n 
3 78  ILE n 
3 79  ALA n 
3 80  PRO n 
3 81  GLY n 
3 82  GLN n 
3 83  THR n 
3 84  GLY n 
3 85  LYS n 
3 86  ILE n 
3 87  ALA n 
3 88  ASP n 
3 89  TYR n 
3 90  ASN n 
3 91  TYR n 
3 92  LYS n 
3 93  LEU n 
3 94  PRO n 
3 95  ASP n 
3 96  ASP n 
3 97  PHE n 
3 98  THR n 
3 99  GLY n 
3 100 CYS n 
3 101 VAL n 
3 102 ILE n 
3 103 ALA n 
3 104 TRP n 
3 105 ASN n 
3 106 SER n 
3 107 ASN n 
3 108 ASN n 
3 109 LEU n 
3 110 ASP n 
3 111 SER n 
3 112 LYS n 
3 113 VAL n 
3 114 GLY n 
3 115 GLY n 
3 116 ASN n 
3 117 TYR n 
3 118 ASN n 
3 119 TYR n 
3 120 LEU n 
3 121 TYR n 
3 122 ARG n 
3 123 LEU n 
3 124 PHE n 
3 125 ARG n 
3 126 LYS n 
3 127 SER n 
3 128 ASN n 
3 129 LEU n 
3 130 LYS n 
3 131 PRO n 
3 132 PHE n 
3 133 GLU n 
3 134 ARG n 
3 135 ASP n 
3 136 ILE n 
3 137 SER n 
3 138 THR n 
3 139 GLU n 
3 140 ILE n 
3 141 TYR n 
3 142 GLN n 
3 143 ALA n 
3 144 GLY n 
3 145 SER n 
3 146 THR n 
3 147 PRO n 
3 148 CYS n 
3 149 ASN n 
3 150 GLY n 
3 151 VAL n 
3 152 GLU n 
3 153 GLY n 
3 154 PHE n 
3 155 ASN n 
3 156 CYS n 
3 157 TYR n 
3 158 PHE n 
3 159 PRO n 
3 160 LEU n 
3 161 GLN n 
3 162 SER n 
3 163 TYR n 
3 164 GLY n 
3 165 PHE n 
3 166 GLN n 
3 167 PRO n 
3 168 THR n 
3 169 ASN n 
3 170 GLY n 
3 171 VAL n 
3 172 GLY n 
3 173 TYR n 
3 174 GLN n 
3 175 PRO n 
3 176 TYR n 
3 177 ARG n 
3 178 VAL n 
3 179 VAL n 
3 180 VAL n 
3 181 LEU n 
3 182 SER n 
3 183 PHE n 
3 184 GLU n 
3 185 LEU n 
3 186 LEU n 
3 187 HIS n 
3 188 ALA n 
3 189 PRO n 
3 190 ALA n 
3 191 THR n 
3 192 VAL n 
3 193 CYS n 
3 194 GLY n 
3 195 PRO n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 231 ?                       ? ?      ? ?       ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ?      ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 214 ?                       ? ?      ? ?       ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ?      ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 195 '2019-nCoV, SARS-CoV-2' ? 'S, 2' ? 2697049 ? ? ? ? 
'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? 
? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   1   1   GLN GLN B . n 
A 1 2   VAL 2   2   2   VAL VAL B . n 
A 1 3   GLN 3   3   3   GLN GLN B . n 
A 1 4   LEU 4   4   4   LEU LEU B . n 
A 1 5   VAL 5   5   5   VAL VAL B . n 
A 1 6   GLN 6   6   6   GLN GLN B . n 
A 1 7   SER 7   7   7   SER SER B . n 
A 1 8   GLY 8   8   8   GLY GLY B . n 
A 1 9   ALA 9   9   9   ALA ALA B . n 
A 1 10  GLU 10  10  10  GLU GLU B . n 
A 1 11  VAL 11  11  11  VAL VAL B . n 
A 1 12  LYS 12  12  12  LYS LYS B . n 
A 1 13  LYS 13  13  13  LYS LYS B . n 
A 1 14  PRO 14  14  14  PRO PRO B . n 
A 1 15  GLY 15  15  15  GLY GLY B . n 
A 1 16  SER 16  16  16  SER SER B . n 
A 1 17  SER 17  17  17  SER SER B . n 
A 1 18  VAL 18  18  18  VAL VAL B . n 
A 1 19  LYS 19  19  19  LYS LYS B . n 
A 1 20  VAL 20  20  20  VAL VAL B . n 
A 1 21  SER 21  21  21  SER SER B . n 
A 1 22  CYS 22  22  22  CYS CYS B . n 
A 1 23  LYS 23  23  23  LYS LYS B . n 
A 1 24  ALA 24  24  24  ALA ALA B . n 
A 1 25  SER 25  25  25  SER SER B . n 
A 1 26  GLY 26  26  26  GLY GLY B . n 
A 1 27  GLY 27  27  27  GLY GLY B . n 
A 1 28  THR 28  28  28  THR THR B . n 
A 1 29  PHE 29  29  29  PHE PHE B . n 
A 1 30  SER 30  30  30  SER SER B . n 
A 1 31  SER 31  31  31  SER SER B . n 
A 1 32  TYR 32  32  32  TYR TYR B . n 
A 1 33  THR 33  33  33  THR THR B . n 
A 1 34  ILE 34  34  34  ILE ILE B . n 
A 1 35  SER 35  35  35  SER SER B . n 
A 1 36  TRP 36  36  36  TRP TRP B . n 
A 1 37  VAL 37  37  37  VAL VAL B . n 
A 1 38  ARG 38  38  38  ARG ARG B . n 
A 1 39  GLN 39  39  39  GLN GLN B . n 
A 1 40  ALA 40  40  40  ALA ALA B . n 
A 1 41  PRO 41  41  41  PRO PRO B . n 
A 1 42  GLY 42  42  42  GLY GLY B . n 
A 1 43  GLN 43  43  43  GLN GLN B . n 
A 1 44  GLY 44  44  44  GLY GLY B . n 
A 1 45  LEU 45  45  45  LEU LEU B . n 
A 1 46  GLU 46  46  46  GLU GLU B . n 
A 1 47  TRP 47  47  47  TRP TRP B . n 
A 1 48  MET 48  48  48  MET MET B . n 
A 1 49  GLY 49  49  49  GLY GLY B . n 
A 1 50  ARG 50  50  50  ARG ARG B . n 
A 1 51  ILE 51  51  51  ILE ILE B . n 
A 1 52  ILE 52  52  52  ILE ILE B . n 
A 1 53  PRO 53  53  53  PRO PRO B . n 
A 1 54  ILE 54  54  54  ILE ILE B . n 
A 1 55  PHE 55  55  55  PHE PHE B . n 
A 1 56  GLY 56  56  56  GLY GLY B . n 
A 1 57  ILE 57  57  57  ILE ILE B . n 
A 1 58  ALA 58  58  58  ALA ALA B . n 
A 1 59  ASN 59  59  59  ASN ASN B . n 
A 1 60  TYR 60  60  60  TYR TYR B . n 
A 1 61  ALA 61  61  61  ALA ALA B . n 
A 1 62  GLN 62  62  62  GLN GLN B . n 
A 1 63  LYS 63  63  63  LYS LYS B . n 
A 1 64  PHE 64  64  64  PHE PHE B . n 
A 1 65  GLN 65  65  65  GLN GLN B . n 
A 1 66  GLY 66  66  66  GLY GLY B . n 
A 1 67  ARG 67  67  67  ARG ARG B . n 
A 1 68  VAL 68  68  68  VAL VAL B . n 
A 1 69  THR 69  69  69  THR THR B . n 
A 1 70  ILE 70  70  70  ILE ILE B . n 
A 1 71  THR 71  71  71  THR THR B . n 
A 1 72  ALA 72  72  72  ALA ALA B . n 
A 1 73  ASP 73  73  73  ASP ASP B . n 
A 1 74  LYS 74  74  74  LYS LYS B . n 
A 1 75  SER 75  75  75  SER SER B . n 
A 1 76  THR 76  76  76  THR THR B . n 
A 1 77  SER 77  77  77  SER SER B . n 
A 1 78  THR 78  78  78  THR THR B . n 
A 1 79  ALA 79  79  79  ALA ALA B . n 
A 1 80  TYR 80  80  80  TYR TYR B . n 
A 1 81  MET 81  81  81  MET MET B . n 
A 1 82  GLU 82  82  82  GLU GLU B . n 
A 1 83  LEU 83  83  83  LEU LEU B . n 
A 1 84  SER 84  84  84  SER SER B . n 
A 1 85  SER 85  85  85  SER SER B . n 
A 1 86  LEU 86  86  86  LEU LEU B . n 
A 1 87  ARG 87  87  87  ARG ARG B . n 
A 1 88  SER 88  88  88  SER SER B . n 
A 1 89  GLU 89  89  89  GLU GLU B . n 
A 1 90  ASP 90  90  90  ASP ASP B . n 
A 1 91  THR 91  91  91  THR THR B . n 
A 1 92  ALA 92  92  92  ALA ALA B . n 
A 1 93  VAL 93  93  93  VAL VAL B . n 
A 1 94  TYR 94  94  94  TYR TYR B . n 
A 1 95  TYR 95  95  95  TYR TYR B . n 
A 1 96  CYS 96  96  96  CYS CYS B . n 
A 1 97  ALA 97  97  97  ALA ALA B . n 
A 1 98  ARG 98  98  98  ARG ARG B . n 
A 1 99  THR 99  99  99  THR THR B . n 
A 1 100 PRO 100 100 100 PRO PRO B . n 
A 1 101 LEU 101 101 101 LEU LEU B . n 
A 1 102 GLU 102 102 102 GLU GLU B . n 
A 1 103 MET 103 103 103 MET MET B . n 
A 1 104 ALA 104 104 104 ALA ALA B . n 
A 1 105 THR 105 105 105 THR THR B . n 
A 1 106 GLU 106 106 106 GLU GLU B . n 
A 1 107 GLU 107 107 107 GLU GLU B . n 
A 1 108 GLY 108 108 108 GLY GLY B . n 
A 1 109 TYR 109 109 109 TYR TYR B . n 
A 1 110 PHE 110 110 110 PHE PHE B . n 
A 1 111 ASP 111 111 111 ASP ASP B . n 
A 1 112 TYR 112 112 112 TYR TYR B . n 
A 1 113 TRP 113 113 113 TRP TRP B . n 
A 1 114 GLY 114 114 114 GLY GLY B . n 
A 1 115 GLN 115 115 115 GLN GLN B . n 
A 1 116 GLY 116 116 116 GLY GLY B . n 
A 1 117 THR 117 117 117 THR THR B . n 
A 1 118 LEU 118 118 118 LEU LEU B . n 
A 1 119 VAL 119 119 119 VAL VAL B . n 
A 1 120 THR 120 120 120 THR THR B . n 
A 1 121 VAL 121 121 121 VAL VAL B . n 
A 1 122 SER 122 122 122 SER SER B . n 
A 1 123 SER 123 123 123 SER SER B . n 
A 1 124 ALA 124 124 124 ALA ALA B . n 
A 1 125 SER 125 125 ?   ?   ?   B . n 
A 1 126 VAL 126 126 ?   ?   ?   B . n 
A 1 127 ARG 127 127 ?   ?   ?   B . n 
A 1 128 SER 128 128 ?   ?   ?   B . n 
A 1 129 THR 129 129 ?   ?   ?   B . n 
A 1 130 LYS 130 130 ?   ?   ?   B . n 
A 1 131 GLY 131 131 ?   ?   ?   B . n 
A 1 132 PRO 132 132 ?   ?   ?   B . n 
A 1 133 SER 133 133 ?   ?   ?   B . n 
A 1 134 VAL 134 134 ?   ?   ?   B . n 
A 1 135 PHE 135 135 ?   ?   ?   B . n 
A 1 136 PRO 136 136 ?   ?   ?   B . n 
A 1 137 LEU 137 137 ?   ?   ?   B . n 
A 1 138 ALA 138 138 ?   ?   ?   B . n 
A 1 139 PRO 139 139 ?   ?   ?   B . n 
A 1 140 SER 140 140 ?   ?   ?   B . n 
A 1 141 SER 141 141 ?   ?   ?   B . n 
A 1 142 LYS 142 142 ?   ?   ?   B . n 
A 1 143 SER 143 143 ?   ?   ?   B . n 
A 1 144 THR 144 144 ?   ?   ?   B . n 
A 1 145 SER 145 145 ?   ?   ?   B . n 
A 1 146 GLY 146 146 ?   ?   ?   B . n 
A 1 147 GLY 147 147 ?   ?   ?   B . n 
A 1 148 THR 148 148 ?   ?   ?   B . n 
A 1 149 ALA 149 149 ?   ?   ?   B . n 
A 1 150 ALA 150 150 ?   ?   ?   B . n 
A 1 151 LEU 151 151 ?   ?   ?   B . n 
A 1 152 GLY 152 152 ?   ?   ?   B . n 
A 1 153 CYS 153 153 ?   ?   ?   B . n 
A 1 154 LEU 154 154 ?   ?   ?   B . n 
A 1 155 VAL 155 155 ?   ?   ?   B . n 
A 1 156 LYS 156 156 ?   ?   ?   B . n 
A 1 157 ASP 157 157 ?   ?   ?   B . n 
A 1 158 TYR 158 158 ?   ?   ?   B . n 
A 1 159 PHE 159 159 ?   ?   ?   B . n 
A 1 160 PRO 160 160 ?   ?   ?   B . n 
A 1 161 GLU 161 161 ?   ?   ?   B . n 
A 1 162 PRO 162 162 ?   ?   ?   B . n 
A 1 163 VAL 163 163 ?   ?   ?   B . n 
A 1 164 THR 164 164 ?   ?   ?   B . n 
A 1 165 VAL 165 165 ?   ?   ?   B . n 
A 1 166 SER 166 166 ?   ?   ?   B . n 
A 1 167 TRP 167 167 ?   ?   ?   B . n 
A 1 168 ASN 168 168 ?   ?   ?   B . n 
A 1 169 SER 169 169 ?   ?   ?   B . n 
A 1 170 GLY 170 170 ?   ?   ?   B . n 
A 1 171 ALA 171 171 ?   ?   ?   B . n 
A 1 172 LEU 172 172 ?   ?   ?   B . n 
A 1 173 THR 173 173 ?   ?   ?   B . n 
A 1 174 SER 174 174 ?   ?   ?   B . n 
A 1 175 GLY 175 175 ?   ?   ?   B . n 
A 1 176 VAL 176 176 ?   ?   ?   B . n 
A 1 177 HIS 177 177 ?   ?   ?   B . n 
A 1 178 THR 178 178 ?   ?   ?   B . n 
A 1 179 PHE 179 179 ?   ?   ?   B . n 
A 1 180 PRO 180 180 ?   ?   ?   B . n 
A 1 181 ALA 181 181 ?   ?   ?   B . n 
A 1 182 VAL 182 182 ?   ?   ?   B . n 
A 1 183 LEU 183 183 ?   ?   ?   B . n 
A 1 184 GLN 184 184 ?   ?   ?   B . n 
A 1 185 SER 185 185 ?   ?   ?   B . n 
A 1 186 SER 186 186 ?   ?   ?   B . n 
A 1 187 GLY 187 187 ?   ?   ?   B . n 
A 1 188 LEU 188 188 ?   ?   ?   B . n 
A 1 189 TYR 189 189 ?   ?   ?   B . n 
A 1 190 SER 190 190 ?   ?   ?   B . n 
A 1 191 LEU 191 191 ?   ?   ?   B . n 
A 1 192 SER 192 192 ?   ?   ?   B . n 
A 1 193 SER 193 193 ?   ?   ?   B . n 
A 1 194 VAL 194 194 ?   ?   ?   B . n 
A 1 195 VAL 195 195 ?   ?   ?   B . n 
A 1 196 THR 196 196 ?   ?   ?   B . n 
A 1 197 VAL 197 197 ?   ?   ?   B . n 
A 1 198 PRO 198 198 ?   ?   ?   B . n 
A 1 199 SER 199 199 ?   ?   ?   B . n 
A 1 200 SER 200 200 ?   ?   ?   B . n 
A 1 201 SER 201 201 ?   ?   ?   B . n 
A 1 202 LEU 202 202 ?   ?   ?   B . n 
A 1 203 GLY 203 203 ?   ?   ?   B . n 
A 1 204 THR 204 204 ?   ?   ?   B . n 
A 1 205 GLN 205 205 ?   ?   ?   B . n 
A 1 206 THR 206 206 ?   ?   ?   B . n 
A 1 207 TYR 207 207 ?   ?   ?   B . n 
A 1 208 ILE 208 208 ?   ?   ?   B . n 
A 1 209 CYS 209 209 ?   ?   ?   B . n 
A 1 210 ASN 210 210 ?   ?   ?   B . n 
A 1 211 VAL 211 211 ?   ?   ?   B . n 
A 1 212 ASN 212 212 ?   ?   ?   B . n 
A 1 213 HIS 213 213 ?   ?   ?   B . n 
A 1 214 LYS 214 214 ?   ?   ?   B . n 
A 1 215 PRO 215 215 ?   ?   ?   B . n 
A 1 216 SER 216 216 ?   ?   ?   B . n 
A 1 217 ASN 217 217 ?   ?   ?   B . n 
A 1 218 THR 218 218 ?   ?   ?   B . n 
A 1 219 LYS 219 219 ?   ?   ?   B . n 
A 1 220 VAL 220 220 ?   ?   ?   B . n 
A 1 221 ASP 221 221 ?   ?   ?   B . n 
A 1 222 LYS 222 222 ?   ?   ?   B . n 
A 1 223 LYS 223 223 ?   ?   ?   B . n 
A 1 224 VAL 224 224 ?   ?   ?   B . n 
A 1 225 GLU 225 225 ?   ?   ?   B . n 
A 1 226 PRO 226 226 ?   ?   ?   B . n 
A 1 227 LYS 227 227 ?   ?   ?   B . n 
A 1 228 SER 228 228 ?   ?   ?   B . n 
A 1 229 CYS 229 229 ?   ?   ?   B . n 
A 1 230 SER 230 230 ?   ?   ?   B . n 
A 1 231 GLY 231 231 ?   ?   ?   B . n 
B 2 1   ASP 1   1   1   ASP ASP C . n 
B 2 2   ILE 2   2   2   ILE ILE C . n 
B 2 3   GLN 3   3   3   GLN GLN C . n 
B 2 4   MET 4   4   4   MET MET C . n 
B 2 5   THR 5   5   5   THR THR C . n 
B 2 6   GLN 6   6   6   GLN GLN C . n 
B 2 7   SER 7   7   7   SER SER C . n 
B 2 8   PRO 8   8   8   PRO PRO C . n 
B 2 9   SER 9   9   9   SER SER C . n 
B 2 10  SER 10  10  10  SER SER C . n 
B 2 11  VAL 11  11  11  VAL VAL C . n 
B 2 12  SER 12  12  12  SER SER C . n 
B 2 13  ALA 13  13  13  ALA ALA C . n 
B 2 14  SER 14  14  14  SER SER C . n 
B 2 15  VAL 15  15  15  VAL VAL C . n 
B 2 16  GLY 16  16  16  GLY GLY C . n 
B 2 17  ASP 17  17  17  ASP ASP C . n 
B 2 18  ARG 18  18  18  ARG ARG C . n 
B 2 19  VAL 19  19  19  VAL VAL C . n 
B 2 20  THR 20  20  20  THR THR C . n 
B 2 21  ILE 21  21  21  ILE ILE C . n 
B 2 22  THR 22  22  22  THR THR C . n 
B 2 23  CYS 23  23  23  CYS CYS C . n 
B 2 24  ARG 24  24  24  ARG ARG C . n 
B 2 25  ALA 25  25  25  ALA ALA C . n 
B 2 26  SER 26  26  26  SER SER C . n 
B 2 27  GLN 27  27  27  GLN GLN C . n 
B 2 28  GLY 28  28  28  GLY GLY C . n 
B 2 29  ILE 29  29  29  ILE ILE C . n 
B 2 30  SER 30  30  30  SER SER C . n 
B 2 31  SER 31  31  31  SER SER C . n 
B 2 32  TRP 32  32  32  TRP TRP C . n 
B 2 33  LEU 33  33  33  LEU LEU C . n 
B 2 34  ALA 34  34  34  ALA ALA C . n 
B 2 35  TRP 35  35  35  TRP TRP C . n 
B 2 36  TYR 36  36  36  TYR TYR C . n 
B 2 37  GLN 37  37  37  GLN GLN C . n 
B 2 38  GLN 38  38  38  GLN GLN C . n 
B 2 39  THR 39  39  39  THR THR C . n 
B 2 40  PRO 40  40  40  PRO PRO C . n 
B 2 41  GLY 41  41  41  GLY GLY C . n 
B 2 42  LYS 42  42  42  LYS LYS C . n 
B 2 43  ALA 43  43  43  ALA ALA C . n 
B 2 44  PRO 44  44  44  PRO PRO C . n 
B 2 45  LYS 45  45  45  LYS LYS C . n 
B 2 46  LEU 46  46  46  LEU LEU C . n 
B 2 47  LEU 47  47  47  LEU LEU C . n 
B 2 48  ILE 48  48  48  ILE ILE C . n 
B 2 49  TYR 49  49  49  TYR TYR C . n 
B 2 50  ALA 50  50  50  ALA ALA C . n 
B 2 51  ALA 51  51  51  ALA ALA C . n 
B 2 52  SER 52  52  52  SER SER C . n 
B 2 53  SER 53  53  53  SER SER C . n 
B 2 54  LEU 54  54  54  LEU LEU C . n 
B 2 55  GLN 55  55  55  GLN GLN C . n 
B 2 56  SER 56  56  56  SER SER C . n 
B 2 57  GLY 57  57  57  GLY GLY C . n 
B 2 58  VAL 58  58  58  VAL VAL C . n 
B 2 59  PRO 59  59  59  PRO PRO C . n 
B 2 60  SER 60  60  60  SER SER C . n 
B 2 61  ARG 61  61  61  ARG ARG C . n 
B 2 62  PHE 62  62  62  PHE PHE C . n 
B 2 63  SER 63  63  63  SER SER C . n 
B 2 64  GLY 64  64  64  GLY GLY C . n 
B 2 65  SER 65  65  65  SER SER C . n 
B 2 66  GLY 66  66  66  GLY GLY C . n 
B 2 67  SER 67  67  67  SER SER C . n 
B 2 68  GLY 68  68  68  GLY GLY C . n 
B 2 69  THR 69  69  69  THR THR C . n 
B 2 70  ASP 70  70  70  ASP ASP C . n 
B 2 71  PHE 71  71  71  PHE PHE C . n 
B 2 72  THR 72  72  72  THR THR C . n 
B 2 73  LEU 73  73  73  LEU LEU C . n 
B 2 74  THR 74  74  74  THR THR C . n 
B 2 75  ILE 75  75  75  ILE ILE C . n 
B 2 76  SER 76  76  76  SER SER C . n 
B 2 77  SER 77  77  77  SER SER C . n 
B 2 78  LEU 78  78  78  LEU LEU C . n 
B 2 79  GLN 79  79  79  GLN GLN C . n 
B 2 80  PRO 80  80  80  PRO PRO C . n 
B 2 81  GLU 81  81  81  GLU GLU C . n 
B 2 82  ASP 82  82  82  ASP ASP C . n 
B 2 83  PHE 83  83  83  PHE PHE C . n 
B 2 84  ALA 84  84  84  ALA ALA C . n 
B 2 85  THR 85  85  85  THR THR C . n 
B 2 86  TYR 86  86  86  TYR TYR C . n 
B 2 87  TYR 87  87  87  TYR TYR C . n 
B 2 88  CYS 88  88  88  CYS CYS C . n 
B 2 89  GLN 89  89  89  GLN GLN C . n 
B 2 90  GLN 90  90  90  GLN GLN C . n 
B 2 91  ALA 91  91  91  ALA ALA C . n 
B 2 92  ASN 92  92  92  ASN ASN C . n 
B 2 93  SER 93  93  93  SER SER C . n 
B 2 94  PHE 94  94  94  PHE PHE C . n 
B 2 95  PRO 95  95  95  PRO PRO C . n 
B 2 96  PHE 96  96  96  PHE PHE C . n 
B 2 97  THR 97  97  97  THR THR C . n 
B 2 98  PHE 98  98  98  PHE PHE C . n 
B 2 99  GLY 99  99  99  GLY GLY C . n 
B 2 100 PRO 100 100 100 PRO PRO C . n 
B 2 101 GLY 101 101 101 GLY GLY C . n 
B 2 102 THR 102 102 102 THR THR C . n 
B 2 103 LYS 103 103 103 LYS LYS C . n 
B 2 104 VAL 104 104 104 VAL VAL C . n 
B 2 105 ASP 105 105 105 ASP ASP C . n 
B 2 106 ILE 106 106 106 ILE ILE C . n 
B 2 107 LYS 107 107 107 LYS LYS C . n 
B 2 108 ARG 108 108 ?   ?   ?   C . n 
B 2 109 THR 109 109 ?   ?   ?   C . n 
B 2 110 VAL 110 110 ?   ?   ?   C . n 
B 2 111 ALA 111 111 ?   ?   ?   C . n 
B 2 112 ALA 112 112 ?   ?   ?   C . n 
B 2 113 PRO 113 113 ?   ?   ?   C . n 
B 2 114 SER 114 114 ?   ?   ?   C . n 
B 2 115 VAL 115 115 ?   ?   ?   C . n 
B 2 116 PHE 116 116 ?   ?   ?   C . n 
B 2 117 ILE 117 117 ?   ?   ?   C . n 
B 2 118 PHE 118 118 ?   ?   ?   C . n 
B 2 119 PRO 119 119 ?   ?   ?   C . n 
B 2 120 PRO 120 120 ?   ?   ?   C . n 
B 2 121 SER 121 121 ?   ?   ?   C . n 
B 2 122 ASP 122 122 ?   ?   ?   C . n 
B 2 123 GLU 123 123 ?   ?   ?   C . n 
B 2 124 GLN 124 124 ?   ?   ?   C . n 
B 2 125 LEU 125 125 ?   ?   ?   C . n 
B 2 126 LYS 126 126 ?   ?   ?   C . n 
B 2 127 SER 127 127 ?   ?   ?   C . n 
B 2 128 GLY 128 128 ?   ?   ?   C . n 
B 2 129 THR 129 129 ?   ?   ?   C . n 
B 2 130 ALA 130 130 ?   ?   ?   C . n 
B 2 131 SER 131 131 ?   ?   ?   C . n 
B 2 132 VAL 132 132 ?   ?   ?   C . n 
B 2 133 VAL 133 133 ?   ?   ?   C . n 
B 2 134 CYS 134 134 ?   ?   ?   C . n 
B 2 135 LEU 135 135 ?   ?   ?   C . n 
B 2 136 LEU 136 136 ?   ?   ?   C . n 
B 2 137 ASN 137 137 ?   ?   ?   C . n 
B 2 138 ASN 138 138 ?   ?   ?   C . n 
B 2 139 PHE 139 139 ?   ?   ?   C . n 
B 2 140 TYR 140 140 ?   ?   ?   C . n 
B 2 141 PRO 141 141 ?   ?   ?   C . n 
B 2 142 ARG 142 142 ?   ?   ?   C . n 
B 2 143 GLU 143 143 ?   ?   ?   C . n 
B 2 144 ALA 144 144 ?   ?   ?   C . n 
B 2 145 LYS 145 145 ?   ?   ?   C . n 
B 2 146 VAL 146 146 ?   ?   ?   C . n 
B 2 147 GLN 147 147 ?   ?   ?   C . n 
B 2 148 TRP 148 148 ?   ?   ?   C . n 
B 2 149 LYS 149 149 ?   ?   ?   C . n 
B 2 150 VAL 150 150 ?   ?   ?   C . n 
B 2 151 ASP 151 151 ?   ?   ?   C . n 
B 2 152 ASN 152 152 ?   ?   ?   C . n 
B 2 153 ALA 153 153 ?   ?   ?   C . n 
B 2 154 LEU 154 154 ?   ?   ?   C . n 
B 2 155 GLN 155 155 ?   ?   ?   C . n 
B 2 156 SER 156 156 ?   ?   ?   C . n 
B 2 157 GLY 157 157 ?   ?   ?   C . n 
B 2 158 ASN 158 158 ?   ?   ?   C . n 
B 2 159 SER 159 159 ?   ?   ?   C . n 
B 2 160 GLN 160 160 ?   ?   ?   C . n 
B 2 161 GLU 161 161 ?   ?   ?   C . n 
B 2 162 SER 162 162 ?   ?   ?   C . n 
B 2 163 VAL 163 163 ?   ?   ?   C . n 
B 2 164 THR 164 164 ?   ?   ?   C . n 
B 2 165 GLU 165 165 ?   ?   ?   C . n 
B 2 166 GLN 166 166 ?   ?   ?   C . n 
B 2 167 ASP 167 167 ?   ?   ?   C . n 
B 2 168 SER 168 168 ?   ?   ?   C . n 
B 2 169 LYS 169 169 ?   ?   ?   C . n 
B 2 170 ASP 170 170 ?   ?   ?   C . n 
B 2 171 SER 171 171 ?   ?   ?   C . n 
B 2 172 THR 172 172 ?   ?   ?   C . n 
B 2 173 TYR 173 173 ?   ?   ?   C . n 
B 2 174 SER 174 174 ?   ?   ?   C . n 
B 2 175 LEU 175 175 ?   ?   ?   C . n 
B 2 176 SER 176 176 ?   ?   ?   C . n 
B 2 177 SER 177 177 ?   ?   ?   C . n 
B 2 178 THR 178 178 ?   ?   ?   C . n 
B 2 179 LEU 179 179 ?   ?   ?   C . n 
B 2 180 THR 180 180 ?   ?   ?   C . n 
B 2 181 LEU 181 181 ?   ?   ?   C . n 
B 2 182 SER 182 182 ?   ?   ?   C . n 
B 2 183 LYS 183 183 ?   ?   ?   C . n 
B 2 184 ALA 184 184 ?   ?   ?   C . n 
B 2 185 ASP 185 185 ?   ?   ?   C . n 
B 2 186 TYR 186 186 ?   ?   ?   C . n 
B 2 187 GLU 187 187 ?   ?   ?   C . n 
B 2 188 LYS 188 188 ?   ?   ?   C . n 
B 2 189 HIS 189 189 ?   ?   ?   C . n 
B 2 190 LYS 190 190 ?   ?   ?   C . n 
B 2 191 VAL 191 191 ?   ?   ?   C . n 
B 2 192 TYR 192 192 ?   ?   ?   C . n 
B 2 193 ALA 193 193 ?   ?   ?   C . n 
B 2 194 CYS 194 194 ?   ?   ?   C . n 
B 2 195 GLU 195 195 ?   ?   ?   C . n 
B 2 196 VAL 196 196 ?   ?   ?   C . n 
B 2 197 THR 197 197 ?   ?   ?   C . n 
B 2 198 HIS 198 198 ?   ?   ?   C . n 
B 2 199 GLN 199 199 ?   ?   ?   C . n 
B 2 200 GLY 200 200 ?   ?   ?   C . n 
B 2 201 LEU 201 201 ?   ?   ?   C . n 
B 2 202 SER 202 202 ?   ?   ?   C . n 
B 2 203 SER 203 203 ?   ?   ?   C . n 
B 2 204 PRO 204 204 ?   ?   ?   C . n 
B 2 205 VAL 205 205 ?   ?   ?   C . n 
B 2 206 THR 206 206 ?   ?   ?   C . n 
B 2 207 LYS 207 207 ?   ?   ?   C . n 
B 2 208 SER 208 208 ?   ?   ?   C . n 
B 2 209 PHE 209 209 ?   ?   ?   C . n 
B 2 210 ASN 210 210 ?   ?   ?   C . n 
B 2 211 ARG 211 211 ?   ?   ?   C . n 
B 2 212 GLY 212 212 ?   ?   ?   C . n 
B 2 213 GLU 213 213 ?   ?   ?   C . n 
B 2 214 CYS 214 214 ?   ?   ?   C . n 
C 3 1   THR 1   333 333 THR THR A . n 
C 3 2   ASN 2   334 334 ASN ASN A . n 
C 3 3   LEU 3   335 335 LEU LEU A . n 
C 3 4   CYS 4   336 336 CYS CYS A . n 
C 3 5   PRO 5   337 337 PRO PRO A . n 
C 3 6   PHE 6   338 338 PHE PHE A . n 
C 3 7   GLY 7   339 339 GLY GLY A . n 
C 3 8   GLU 8   340 340 GLU GLU A . n 
C 3 9   VAL 9   341 341 VAL VAL A . n 
C 3 10  PHE 10  342 342 PHE PHE A . n 
C 3 11  ASN 11  343 343 ASN ASN A . n 
C 3 12  ALA 12  344 344 ALA ALA A . n 
C 3 13  THR 13  345 345 THR THR A . n 
C 3 14  ARG 14  346 346 ARG ARG A . n 
C 3 15  PHE 15  347 347 PHE PHE A . n 
C 3 16  ALA 16  348 348 ALA ALA A . n 
C 3 17  SER 17  349 349 SER SER A . n 
C 3 18  VAL 18  350 350 VAL VAL A . n 
C 3 19  TYR 19  351 351 TYR TYR A . n 
C 3 20  ALA 20  352 352 ALA ALA A . n 
C 3 21  TRP 21  353 353 TRP TRP A . n 
C 3 22  ASN 22  354 354 ASN ASN A . n 
C 3 23  ARG 23  355 355 ARG ARG A . n 
C 3 24  LYS 24  356 356 LYS LYS A . n 
C 3 25  ARG 25  357 357 ARG ARG A . n 
C 3 26  ILE 26  358 358 ILE ILE A . n 
C 3 27  SER 27  359 359 SER SER A . n 
C 3 28  ASN 28  360 360 ASN ASN A . n 
C 3 29  CYS 29  361 361 CYS CYS A . n 
C 3 30  VAL 30  362 362 VAL VAL A . n 
C 3 31  ALA 31  363 363 ALA ALA A . n 
C 3 32  ASP 32  364 364 ASP ASP A . n 
C 3 33  TYR 33  365 365 TYR TYR A . n 
C 3 34  SER 34  366 366 SER SER A . n 
C 3 35  VAL 35  367 367 VAL VAL A . n 
C 3 36  LEU 36  368 368 LEU LEU A . n 
C 3 37  TYR 37  369 369 TYR TYR A . n 
C 3 38  ASN 38  370 370 ASN ASN A . n 
C 3 39  SER 39  371 371 SER SER A . n 
C 3 40  ALA 40  372 372 ALA ALA A . n 
C 3 41  SER 41  373 373 SER SER A . n 
C 3 42  PHE 42  374 374 PHE PHE A . n 
C 3 43  SER 43  375 375 SER SER A . n 
C 3 44  THR 44  376 376 THR THR A . n 
C 3 45  PHE 45  377 377 PHE PHE A . n 
C 3 46  LYS 46  378 378 LYS LYS A . n 
C 3 47  CYS 47  379 379 CYS CYS A . n 
C 3 48  TYR 48  380 380 TYR TYR A . n 
C 3 49  GLY 49  381 381 GLY GLY A . n 
C 3 50  VAL 50  382 382 VAL VAL A . n 
C 3 51  SER 51  383 383 SER SER A . n 
C 3 52  PRO 52  384 384 PRO PRO A . n 
C 3 53  THR 53  385 385 THR THR A . n 
C 3 54  LYS 54  386 386 LYS LYS A . n 
C 3 55  LEU 55  387 387 LEU LEU A . n 
C 3 56  ASN 56  388 388 ASN ASN A . n 
C 3 57  ASP 57  389 389 ASP ASP A . n 
C 3 58  LEU 58  390 390 LEU LEU A . n 
C 3 59  CYS 59  391 391 CYS CYS A . n 
C 3 60  PHE 60  392 392 PHE PHE A . n 
C 3 61  THR 61  393 393 THR THR A . n 
C 3 62  ASN 62  394 394 ASN ASN A . n 
C 3 63  VAL 63  395 395 VAL VAL A . n 
C 3 64  TYR 64  396 396 TYR TYR A . n 
C 3 65  ALA 65  397 397 ALA ALA A . n 
C 3 66  ASP 66  398 398 ASP ASP A . n 
C 3 67  SER 67  399 399 SER SER A . n 
C 3 68  PHE 68  400 400 PHE PHE A . n 
C 3 69  VAL 69  401 401 VAL VAL A . n 
C 3 70  ILE 70  402 402 ILE ILE A . n 
C 3 71  ARG 71  403 403 ARG ARG A . n 
C 3 72  GLY 72  404 404 GLY GLY A . n 
C 3 73  ASP 73  405 405 ASP ASP A . n 
C 3 74  GLU 74  406 406 GLU GLU A . n 
C 3 75  VAL 75  407 407 VAL VAL A . n 
C 3 76  ARG 76  408 408 ARG ARG A . n 
C 3 77  GLN 77  409 409 GLN GLN A . n 
C 3 78  ILE 78  410 410 ILE ILE A . n 
C 3 79  ALA 79  411 411 ALA ALA A . n 
C 3 80  PRO 80  412 412 PRO PRO A . n 
C 3 81  GLY 81  413 413 GLY GLY A . n 
C 3 82  GLN 82  414 414 GLN GLN A . n 
C 3 83  THR 83  415 415 THR THR A . n 
C 3 84  GLY 84  416 416 GLY GLY A . n 
C 3 85  LYS 85  417 417 LYS LYS A . n 
C 3 86  ILE 86  418 418 ILE ILE A . n 
C 3 87  ALA 87  419 419 ALA ALA A . n 
C 3 88  ASP 88  420 420 ASP ASP A . n 
C 3 89  TYR 89  421 421 TYR TYR A . n 
C 3 90  ASN 90  422 422 ASN ASN A . n 
C 3 91  TYR 91  423 423 TYR TYR A . n 
C 3 92  LYS 92  424 424 LYS LYS A . n 
C 3 93  LEU 93  425 425 LEU LEU A . n 
C 3 94  PRO 94  426 426 PRO PRO A . n 
C 3 95  ASP 95  427 427 ASP ASP A . n 
C 3 96  ASP 96  428 428 ASP ASP A . n 
C 3 97  PHE 97  429 429 PHE PHE A . n 
C 3 98  THR 98  430 430 THR THR A . n 
C 3 99  GLY 99  431 431 GLY GLY A . n 
C 3 100 CYS 100 432 432 CYS CYS A . n 
C 3 101 VAL 101 433 433 VAL VAL A . n 
C 3 102 ILE 102 434 434 ILE ILE A . n 
C 3 103 ALA 103 435 435 ALA ALA A . n 
C 3 104 TRP 104 436 436 TRP TRP A . n 
C 3 105 ASN 105 437 437 ASN ASN A . n 
C 3 106 SER 106 438 438 SER SER A . n 
C 3 107 ASN 107 439 439 ASN ASN A . n 
C 3 108 ASN 108 440 440 ASN ASN A . n 
C 3 109 LEU 109 441 441 LEU LEU A . n 
C 3 110 ASP 110 442 442 ASP ASP A . n 
C 3 111 SER 111 443 443 SER SER A . n 
C 3 112 LYS 112 444 444 LYS LYS A . n 
C 3 113 VAL 113 445 445 VAL VAL A . n 
C 3 114 GLY 114 446 446 GLY GLY A . n 
C 3 115 GLY 115 447 447 GLY GLY A . n 
C 3 116 ASN 116 448 448 ASN ASN A . n 
C 3 117 TYR 117 449 449 TYR TYR A . n 
C 3 118 ASN 118 450 450 ASN ASN A . n 
C 3 119 TYR 119 451 451 TYR TYR A . n 
C 3 120 LEU 120 452 452 LEU LEU A . n 
C 3 121 TYR 121 453 453 TYR TYR A . n 
C 3 122 ARG 122 454 454 ARG ARG A . n 
C 3 123 LEU 123 455 455 LEU LEU A . n 
C 3 124 PHE 124 456 456 PHE PHE A . n 
C 3 125 ARG 125 457 457 ARG ARG A . n 
C 3 126 LYS 126 458 458 LYS LYS A . n 
C 3 127 SER 127 459 459 SER SER A . n 
C 3 128 ASN 128 460 460 ASN ASN A . n 
C 3 129 LEU 129 461 461 LEU LEU A . n 
C 3 130 LYS 130 462 462 LYS LYS A . n 
C 3 131 PRO 131 463 463 PRO PRO A . n 
C 3 132 PHE 132 464 464 PHE PHE A . n 
C 3 133 GLU 133 465 465 GLU GLU A . n 
C 3 134 ARG 134 466 466 ARG ARG A . n 
C 3 135 ASP 135 467 467 ASP ASP A . n 
C 3 136 ILE 136 468 468 ILE ILE A . n 
C 3 137 SER 137 469 469 SER SER A . n 
C 3 138 THR 138 470 470 THR THR A . n 
C 3 139 GLU 139 471 471 GLU GLU A . n 
C 3 140 ILE 140 472 472 ILE ILE A . n 
C 3 141 TYR 141 473 473 TYR TYR A . n 
C 3 142 GLN 142 474 474 GLN GLN A . n 
C 3 143 ALA 143 475 475 ALA ALA A . n 
C 3 144 GLY 144 476 476 GLY GLY A . n 
C 3 145 SER 145 477 477 SER SER A . n 
C 3 146 THR 146 478 478 THR THR A . n 
C 3 147 PRO 147 479 479 PRO PRO A . n 
C 3 148 CYS 148 480 480 CYS CYS A . n 
C 3 149 ASN 149 481 481 ASN ASN A . n 
C 3 150 GLY 150 482 482 GLY GLY A . n 
C 3 151 VAL 151 483 483 VAL VAL A . n 
C 3 152 GLU 152 484 484 GLU GLU A . n 
C 3 153 GLY 153 485 485 GLY GLY A . n 
C 3 154 PHE 154 486 486 PHE PHE A . n 
C 3 155 ASN 155 487 487 ASN ASN A . n 
C 3 156 CYS 156 488 488 CYS CYS A . n 
C 3 157 TYR 157 489 489 TYR TYR A . n 
C 3 158 PHE 158 490 490 PHE PHE A . n 
C 3 159 PRO 159 491 491 PRO PRO A . n 
C 3 160 LEU 160 492 492 LEU LEU A . n 
C 3 161 GLN 161 493 493 GLN GLN A . n 
C 3 162 SER 162 494 494 SER SER A . n 
C 3 163 TYR 163 495 495 TYR TYR A . n 
C 3 164 GLY 164 496 496 GLY GLY A . n 
C 3 165 PHE 165 497 497 PHE PHE A . n 
C 3 166 GLN 166 498 498 GLN GLN A . n 
C 3 167 PRO 167 499 499 PRO PRO A . n 
C 3 168 THR 168 500 500 THR THR A . n 
C 3 169 ASN 169 501 501 ASN ASN A . n 
C 3 170 GLY 170 502 502 GLY GLY A . n 
C 3 171 VAL 171 503 503 VAL VAL A . n 
C 3 172 GLY 172 504 504 GLY GLY A . n 
C 3 173 TYR 173 505 505 TYR TYR A . n 
C 3 174 GLN 174 506 506 GLN GLN A . n 
C 3 175 PRO 175 507 507 PRO PRO A . n 
C 3 176 TYR 176 508 508 TYR TYR A . n 
C 3 177 ARG 177 509 509 ARG ARG A . n 
C 3 178 VAL 178 510 510 VAL VAL A . n 
C 3 179 VAL 179 511 511 VAL VAL A . n 
C 3 180 VAL 180 512 512 VAL VAL A . n 
C 3 181 LEU 181 513 513 LEU LEU A . n 
C 3 182 SER 182 514 514 SER SER A . n 
C 3 183 PHE 183 515 515 PHE PHE A . n 
C 3 184 GLU 184 516 516 GLU GLU A . n 
C 3 185 LEU 185 517 517 LEU LEU A . n 
C 3 186 LEU 186 518 ?   ?   ?   A . n 
C 3 187 HIS 187 519 ?   ?   ?   A . n 
C 3 188 ALA 188 520 520 ALA ALA A . n 
C 3 189 PRO 189 521 521 PRO PRO A . n 
C 3 190 ALA 190 522 522 ALA ALA A . n 
C 3 191 THR 191 523 523 THR THR A . n 
C 3 192 VAL 192 524 524 VAL VAL A . n 
C 3 193 CYS 193 525 525 CYS CYS A . n 
C 3 194 GLY 194 526 526 GLY GLY A . n 
C 3 195 PRO 195 527 527 PRO PRO A . n 
D 3 1   THR 1   333 333 THR THR D . n 
D 3 2   ASN 2   334 334 ASN ASN D . n 
D 3 3   LEU 3   335 335 LEU LEU D . n 
D 3 4   CYS 4   336 336 CYS CYS D . n 
D 3 5   PRO 5   337 337 PRO PRO D . n 
D 3 6   PHE 6   338 338 PHE PHE D . n 
D 3 7   GLY 7   339 339 GLY GLY D . n 
D 3 8   GLU 8   340 340 GLU GLU D . n 
D 3 9   VAL 9   341 341 VAL VAL D . n 
D 3 10  PHE 10  342 342 PHE PHE D . n 
D 3 11  ASN 11  343 343 ASN ASN D . n 
D 3 12  ALA 12  344 344 ALA ALA D . n 
D 3 13  THR 13  345 345 THR THR D . n 
D 3 14  ARG 14  346 346 ARG ARG D . n 
D 3 15  PHE 15  347 347 PHE PHE D . n 
D 3 16  ALA 16  348 348 ALA ALA D . n 
D 3 17  SER 17  349 349 SER SER D . n 
D 3 18  VAL 18  350 350 VAL VAL D . n 
D 3 19  TYR 19  351 351 TYR TYR D . n 
D 3 20  ALA 20  352 352 ALA ALA D . n 
D 3 21  TRP 21  353 353 TRP TRP D . n 
D 3 22  ASN 22  354 354 ASN ASN D . n 
D 3 23  ARG 23  355 355 ARG ARG D . n 
D 3 24  LYS 24  356 ?   ?   ?   D . n 
D 3 25  ARG 25  357 ?   ?   ?   D . n 
D 3 26  ILE 26  358 ?   ?   ?   D . n 
D 3 27  SER 27  359 359 SER SER D . n 
D 3 28  ASN 28  360 360 ASN ASN D . n 
D 3 29  CYS 29  361 361 CYS CYS D . n 
D 3 30  VAL 30  362 362 VAL VAL D . n 
D 3 31  ALA 31  363 363 ALA ALA D . n 
D 3 32  ASP 32  364 364 ASP ASP D . n 
D 3 33  TYR 33  365 365 TYR TYR D . n 
D 3 34  SER 34  366 366 SER SER D . n 
D 3 35  VAL 35  367 367 VAL VAL D . n 
D 3 36  LEU 36  368 ?   ?   ?   D . n 
D 3 37  TYR 37  369 ?   ?   ?   D . n 
D 3 38  ASN 38  370 ?   ?   ?   D . n 
D 3 39  SER 39  371 ?   ?   ?   D . n 
D 3 40  ALA 40  372 ?   ?   ?   D . n 
D 3 41  SER 41  373 ?   ?   ?   D . n 
D 3 42  PHE 42  374 ?   ?   ?   D . n 
D 3 43  SER 43  375 375 SER SER D . n 
D 3 44  THR 44  376 376 THR THR D . n 
D 3 45  PHE 45  377 377 PHE PHE D . n 
D 3 46  LYS 46  378 378 LYS LYS D . n 
D 3 47  CYS 47  379 379 CYS CYS D . n 
D 3 48  TYR 48  380 380 TYR TYR D . n 
D 3 49  GLY 49  381 381 GLY GLY D . n 
D 3 50  VAL 50  382 382 VAL VAL D . n 
D 3 51  SER 51  383 383 SER SER D . n 
D 3 52  PRO 52  384 384 PRO PRO D . n 
D 3 53  THR 53  385 385 THR THR D . n 
D 3 54  LYS 54  386 ?   ?   ?   D . n 
D 3 55  LEU 55  387 ?   ?   ?   D . n 
D 3 56  ASN 56  388 ?   ?   ?   D . n 
D 3 57  ASP 57  389 ?   ?   ?   D . n 
D 3 58  LEU 58  390 390 LEU LEU D . n 
D 3 59  CYS 59  391 391 CYS CYS D . n 
D 3 60  PHE 60  392 392 PHE PHE D . n 
D 3 61  THR 61  393 393 THR THR D . n 
D 3 62  ASN 62  394 394 ASN ASN D . n 
D 3 63  VAL 63  395 395 VAL VAL D . n 
D 3 64  TYR 64  396 396 TYR TYR D . n 
D 3 65  ALA 65  397 397 ALA ALA D . n 
D 3 66  ASP 66  398 398 ASP ASP D . n 
D 3 67  SER 67  399 399 SER SER D . n 
D 3 68  PHE 68  400 400 PHE PHE D . n 
D 3 69  VAL 69  401 401 VAL VAL D . n 
D 3 70  ILE 70  402 402 ILE ILE D . n 
D 3 71  ARG 71  403 403 ARG ARG D . n 
D 3 72  GLY 72  404 404 GLY GLY D . n 
D 3 73  ASP 73  405 405 ASP ASP D . n 
D 3 74  GLU 74  406 406 GLU GLU D . n 
D 3 75  VAL 75  407 407 VAL VAL D . n 
D 3 76  ARG 76  408 408 ARG ARG D . n 
D 3 77  GLN 77  409 409 GLN GLN D . n 
D 3 78  ILE 78  410 410 ILE ILE D . n 
D 3 79  ALA 79  411 411 ALA ALA D . n 
D 3 80  PRO 80  412 412 PRO PRO D . n 
D 3 81  GLY 81  413 413 GLY GLY D . n 
D 3 82  GLN 82  414 414 GLN GLN D . n 
D 3 83  THR 83  415 415 THR THR D . n 
D 3 84  GLY 84  416 416 GLY GLY D . n 
D 3 85  LYS 85  417 417 LYS LYS D . n 
D 3 86  ILE 86  418 418 ILE ILE D . n 
D 3 87  ALA 87  419 419 ALA ALA D . n 
D 3 88  ASP 88  420 420 ASP ASP D . n 
D 3 89  TYR 89  421 421 TYR TYR D . n 
D 3 90  ASN 90  422 422 ASN ASN D . n 
D 3 91  TYR 91  423 423 TYR TYR D . n 
D 3 92  LYS 92  424 424 LYS LYS D . n 
D 3 93  LEU 93  425 425 LEU LEU D . n 
D 3 94  PRO 94  426 426 PRO PRO D . n 
D 3 95  ASP 95  427 427 ASP ASP D . n 
D 3 96  ASP 96  428 428 ASP ASP D . n 
D 3 97  PHE 97  429 429 PHE PHE D . n 
D 3 98  THR 98  430 430 THR THR D . n 
D 3 99  GLY 99  431 431 GLY GLY D . n 
D 3 100 CYS 100 432 432 CYS CYS D . n 
D 3 101 VAL 101 433 433 VAL VAL D . n 
D 3 102 ILE 102 434 434 ILE ILE D . n 
D 3 103 ALA 103 435 435 ALA ALA D . n 
D 3 104 TRP 104 436 436 TRP TRP D . n 
D 3 105 ASN 105 437 437 ASN ASN D . n 
D 3 106 SER 106 438 438 SER SER D . n 
D 3 107 ASN 107 439 439 ASN ASN D . n 
D 3 108 ASN 108 440 440 ASN ASN D . n 
D 3 109 LEU 109 441 441 LEU LEU D . n 
D 3 110 ASP 110 442 442 ASP ASP D . n 
D 3 111 SER 111 443 443 SER SER D . n 
D 3 112 LYS 112 444 444 LYS LYS D . n 
D 3 113 VAL 113 445 ?   ?   ?   D . n 
D 3 114 GLY 114 446 ?   ?   ?   D . n 
D 3 115 GLY 115 447 447 GLY GLY D . n 
D 3 116 ASN 116 448 448 ASN ASN D . n 
D 3 117 TYR 117 449 449 TYR TYR D . n 
D 3 118 ASN 118 450 450 ASN ASN D . n 
D 3 119 TYR 119 451 451 TYR TYR D . n 
D 3 120 LEU 120 452 452 LEU LEU D . n 
D 3 121 TYR 121 453 453 TYR TYR D . n 
D 3 122 ARG 122 454 454 ARG ARG D . n 
D 3 123 LEU 123 455 455 LEU LEU D . n 
D 3 124 PHE 124 456 456 PHE PHE D . n 
D 3 125 ARG 125 457 457 ARG ARG D . n 
D 3 126 LYS 126 458 458 LYS LYS D . n 
D 3 127 SER 127 459 459 SER SER D . n 
D 3 128 ASN 128 460 460 ASN ASN D . n 
D 3 129 LEU 129 461 461 LEU LEU D . n 
D 3 130 LYS 130 462 462 LYS LYS D . n 
D 3 131 PRO 131 463 463 PRO PRO D . n 
D 3 132 PHE 132 464 ?   ?   ?   D . n 
D 3 133 GLU 133 465 ?   ?   ?   D . n 
D 3 134 ARG 134 466 ?   ?   ?   D . n 
D 3 135 ASP 135 467 ?   ?   ?   D . n 
D 3 136 ILE 136 468 ?   ?   ?   D . n 
D 3 137 SER 137 469 ?   ?   ?   D . n 
D 3 138 THR 138 470 ?   ?   ?   D . n 
D 3 139 GLU 139 471 ?   ?   ?   D . n 
D 3 140 ILE 140 472 ?   ?   ?   D . n 
D 3 141 TYR 141 473 ?   ?   ?   D . n 
D 3 142 GLN 142 474 ?   ?   ?   D . n 
D 3 143 ALA 143 475 ?   ?   ?   D . n 
D 3 144 GLY 144 476 ?   ?   ?   D . n 
D 3 145 SER 145 477 ?   ?   ?   D . n 
D 3 146 THR 146 478 ?   ?   ?   D . n 
D 3 147 PRO 147 479 ?   ?   ?   D . n 
D 3 148 CYS 148 480 ?   ?   ?   D . n 
D 3 149 ASN 149 481 ?   ?   ?   D . n 
D 3 150 GLY 150 482 ?   ?   ?   D . n 
D 3 151 VAL 151 483 ?   ?   ?   D . n 
D 3 152 GLU 152 484 ?   ?   ?   D . n 
D 3 153 GLY 153 485 ?   ?   ?   D . n 
D 3 154 PHE 154 486 ?   ?   ?   D . n 
D 3 155 ASN 155 487 ?   ?   ?   D . n 
D 3 156 CYS 156 488 ?   ?   ?   D . n 
D 3 157 TYR 157 489 ?   ?   ?   D . n 
D 3 158 PHE 158 490 ?   ?   ?   D . n 
D 3 159 PRO 159 491 ?   ?   ?   D . n 
D 3 160 LEU 160 492 ?   ?   ?   D . n 
D 3 161 GLN 161 493 ?   ?   ?   D . n 
D 3 162 SER 162 494 ?   ?   ?   D . n 
D 3 163 TYR 163 495 ?   ?   ?   D . n 
D 3 164 GLY 164 496 ?   ?   ?   D . n 
D 3 165 PHE 165 497 ?   ?   ?   D . n 
D 3 166 GLN 166 498 498 GLN GLN D . n 
D 3 167 PRO 167 499 499 PRO PRO D . n 
D 3 168 THR 168 500 500 THR THR D . n 
D 3 169 ASN 169 501 501 ASN ASN D . n 
D 3 170 GLY 170 502 502 GLY GLY D . n 
D 3 171 VAL 171 503 503 VAL VAL D . n 
D 3 172 GLY 172 504 504 GLY GLY D . n 
D 3 173 TYR 173 505 505 TYR TYR D . n 
D 3 174 GLN 174 506 506 GLN GLN D . n 
D 3 175 PRO 175 507 507 PRO PRO D . n 
D 3 176 TYR 176 508 508 TYR TYR D . n 
D 3 177 ARG 177 509 509 ARG ARG D . n 
D 3 178 VAL 178 510 510 VAL VAL D . n 
D 3 179 VAL 179 511 511 VAL VAL D . n 
D 3 180 VAL 180 512 512 VAL VAL D . n 
D 3 181 LEU 181 513 513 LEU LEU D . n 
D 3 182 SER 182 514 514 SER SER D . n 
D 3 183 PHE 183 515 515 PHE PHE D . n 
D 3 184 GLU 184 516 516 GLU GLU D . n 
D 3 185 LEU 185 517 517 LEU LEU D . n 
D 3 186 LEU 186 518 ?   ?   ?   D . n 
D 3 187 HIS 187 519 ?   ?   ?   D . n 
D 3 188 ALA 188 520 ?   ?   ?   D . n 
D 3 189 PRO 189 521 ?   ?   ?   D . n 
D 3 190 ALA 190 522 ?   ?   ?   D . n 
D 3 191 THR 191 523 ?   ?   ?   D . n 
D 3 192 VAL 192 524 ?   ?   ?   D . n 
D 3 193 CYS 193 525 ?   ?   ?   D . n 
D 3 194 GLY 194 526 ?   ?   ?   D . n 
D 3 195 PRO 195 527 ?   ?   ?   D . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 B GLN 1   ? CG  ? A GLN 1   CG  
2   1 Y 1 B GLN 1   ? CD  ? A GLN 1   CD  
3   1 Y 1 B GLN 1   ? OE1 ? A GLN 1   OE1 
4   1 Y 1 B GLN 1   ? NE2 ? A GLN 1   NE2 
5   1 Y 1 B LYS 13  ? CG  ? A LYS 13  CG  
6   1 Y 1 B LYS 13  ? CD  ? A LYS 13  CD  
7   1 Y 1 B LYS 13  ? CE  ? A LYS 13  CE  
8   1 Y 1 B LYS 13  ? NZ  ? A LYS 13  NZ  
9   1 Y 1 B LYS 19  ? CG  ? A LYS 19  CG  
10  1 Y 1 B LYS 19  ? CD  ? A LYS 19  CD  
11  1 Y 1 B LYS 19  ? CE  ? A LYS 19  CE  
12  1 Y 1 B LYS 19  ? NZ  ? A LYS 19  NZ  
13  1 Y 1 B LYS 23  ? CG  ? A LYS 23  CG  
14  1 Y 1 B LYS 23  ? CD  ? A LYS 23  CD  
15  1 Y 1 B LYS 23  ? CE  ? A LYS 23  CE  
16  1 Y 1 B LYS 23  ? NZ  ? A LYS 23  NZ  
17  1 Y 1 B PHE 29  ? CG  ? A PHE 29  CG  
18  1 Y 1 B PHE 29  ? CD1 ? A PHE 29  CD1 
19  1 Y 1 B PHE 29  ? CD2 ? A PHE 29  CD2 
20  1 Y 1 B PHE 29  ? CE1 ? A PHE 29  CE1 
21  1 Y 1 B PHE 29  ? CE2 ? A PHE 29  CE2 
22  1 Y 1 B PHE 29  ? CZ  ? A PHE 29  CZ  
23  1 Y 1 B LYS 74  ? CG  ? A LYS 74  CG  
24  1 Y 1 B LYS 74  ? CD  ? A LYS 74  CD  
25  1 Y 1 B LYS 74  ? CE  ? A LYS 74  CE  
26  1 Y 1 B LYS 74  ? NZ  ? A LYS 74  NZ  
27  1 Y 1 B LEU 86  ? CG  ? A LEU 86  CG  
28  1 Y 1 B LEU 86  ? CD1 ? A LEU 86  CD1 
29  1 Y 1 B LEU 86  ? CD2 ? A LEU 86  CD2 
30  1 Y 1 B ARG 87  ? CG  ? A ARG 87  CG  
31  1 Y 1 B ARG 87  ? CD  ? A ARG 87  CD  
32  1 Y 1 B ARG 87  ? NE  ? A ARG 87  NE  
33  1 Y 1 B ARG 87  ? CZ  ? A ARG 87  CZ  
34  1 Y 1 B ARG 87  ? NH1 ? A ARG 87  NH1 
35  1 Y 1 B ARG 87  ? NH2 ? A ARG 87  NH2 
36  1 Y 1 B GLU 89  ? CG  ? A GLU 89  CG  
37  1 Y 1 B GLU 89  ? CD  ? A GLU 89  CD  
38  1 Y 1 B GLU 89  ? OE1 ? A GLU 89  OE1 
39  1 Y 1 B GLU 89  ? OE2 ? A GLU 89  OE2 
40  1 Y 1 B ASP 90  ? CG  ? A ASP 90  CG  
41  1 Y 1 B ASP 90  ? OD1 ? A ASP 90  OD1 
42  1 Y 1 B ASP 90  ? OD2 ? A ASP 90  OD2 
43  1 Y 1 B THR 91  ? OG1 ? A THR 91  OG1 
44  1 Y 1 B THR 91  ? CG2 ? A THR 91  CG2 
45  1 Y 1 B THR 99  ? OG1 ? A THR 99  OG1 
46  1 Y 1 B THR 99  ? CG2 ? A THR 99  CG2 
47  1 Y 1 B GLU 102 ? CG  ? A GLU 102 CG  
48  1 Y 1 B GLU 102 ? CD  ? A GLU 102 CD  
49  1 Y 1 B GLU 102 ? OE1 ? A GLU 102 OE1 
50  1 Y 1 B GLU 102 ? OE2 ? A GLU 102 OE2 
51  1 Y 1 B MET 103 ? CG  ? A MET 103 CG  
52  1 Y 1 B MET 103 ? SD  ? A MET 103 SD  
53  1 Y 1 B MET 103 ? CE  ? A MET 103 CE  
54  1 Y 1 B GLU 107 ? CG  ? A GLU 107 CG  
55  1 Y 1 B GLU 107 ? CD  ? A GLU 107 CD  
56  1 Y 1 B GLU 107 ? OE1 ? A GLU 107 OE1 
57  1 Y 1 B GLU 107 ? OE2 ? A GLU 107 OE2 
58  1 Y 1 B LEU 118 ? CG  ? A LEU 118 CG  
59  1 Y 1 B LEU 118 ? CD1 ? A LEU 118 CD1 
60  1 Y 1 B LEU 118 ? CD2 ? A LEU 118 CD2 
61  1 Y 1 C ASP 1   ? CG  ? B ASP 1   CG  
62  1 Y 1 C ASP 1   ? OD1 ? B ASP 1   OD1 
63  1 Y 1 C ASP 1   ? OD2 ? B ASP 1   OD2 
64  1 Y 1 C VAL 19  ? CG1 ? B VAL 19  CG1 
65  1 Y 1 C VAL 19  ? CG2 ? B VAL 19  CG2 
66  1 Y 1 C ARG 24  ? CG  ? B ARG 24  CG  
67  1 Y 1 C ARG 24  ? CD  ? B ARG 24  CD  
68  1 Y 1 C ARG 24  ? NE  ? B ARG 24  NE  
69  1 Y 1 C ARG 24  ? CZ  ? B ARG 24  CZ  
70  1 Y 1 C ARG 24  ? NH1 ? B ARG 24  NH1 
71  1 Y 1 C ARG 24  ? NH2 ? B ARG 24  NH2 
72  1 Y 1 C GLN 27  ? CG  ? B GLN 27  CG  
73  1 Y 1 C GLN 27  ? CD  ? B GLN 27  CD  
74  1 Y 1 C GLN 27  ? OE1 ? B GLN 27  OE1 
75  1 Y 1 C GLN 27  ? NE2 ? B GLN 27  NE2 
76  1 Y 1 C SER 30  ? OG  ? B SER 30  OG  
77  1 Y 1 C LYS 42  ? CG  ? B LYS 42  CG  
78  1 Y 1 C LYS 42  ? CD  ? B LYS 42  CD  
79  1 Y 1 C LYS 42  ? CE  ? B LYS 42  CE  
80  1 Y 1 C LYS 42  ? NZ  ? B LYS 42  NZ  
81  1 Y 1 C SER 53  ? OG  ? B SER 53  OG  
82  1 Y 1 C SER 67  ? OG  ? B SER 67  OG  
83  1 Y 1 C THR 69  ? OG1 ? B THR 69  OG1 
84  1 Y 1 C THR 69  ? CG2 ? B THR 69  CG2 
85  1 Y 1 C ASP 70  ? CG  ? B ASP 70  CG  
86  1 Y 1 C ASP 70  ? OD1 ? B ASP 70  OD1 
87  1 Y 1 C ASP 70  ? OD2 ? B ASP 70  OD2 
88  1 Y 1 C GLN 79  ? CG  ? B GLN 79  CG  
89  1 Y 1 C GLN 79  ? CD  ? B GLN 79  CD  
90  1 Y 1 C GLN 79  ? OE1 ? B GLN 79  OE1 
91  1 Y 1 C GLN 79  ? NE2 ? B GLN 79  NE2 
92  1 Y 1 C ASP 82  ? CG  ? B ASP 82  CG  
93  1 Y 1 C ASP 82  ? OD1 ? B ASP 82  OD1 
94  1 Y 1 C ASP 82  ? OD2 ? B ASP 82  OD2 
95  1 Y 1 C SER 93  ? OG  ? B SER 93  OG  
96  1 Y 1 C LYS 103 ? CG  ? B LYS 103 CG  
97  1 Y 1 C LYS 103 ? CD  ? B LYS 103 CD  
98  1 Y 1 C LYS 103 ? CE  ? B LYS 103 CE  
99  1 Y 1 C LYS 103 ? NZ  ? B LYS 103 NZ  
100 1 Y 1 C LYS 107 ? CG  ? B LYS 107 CG  
101 1 Y 1 C LYS 107 ? CD  ? B LYS 107 CD  
102 1 Y 1 C LYS 107 ? CE  ? B LYS 107 CE  
103 1 Y 1 C LYS 107 ? NZ  ? B LYS 107 NZ  
104 1 Y 1 A ASP 389 ? CG  ? C ASP 57  CG  
105 1 Y 1 A ASP 389 ? OD1 ? C ASP 57  OD1 
106 1 Y 1 A ASP 389 ? OD2 ? C ASP 57  OD2 
107 1 Y 1 A GLU 406 ? CG  ? C GLU 74  CG  
108 1 Y 1 A GLU 406 ? CD  ? C GLU 74  CD  
109 1 Y 1 A GLU 406 ? OE1 ? C GLU 74  OE1 
110 1 Y 1 A GLU 406 ? OE2 ? C GLU 74  OE2 
111 1 Y 1 A THR 415 ? OG1 ? C THR 83  OG1 
112 1 Y 1 A THR 415 ? CG2 ? C THR 83  CG2 
113 1 Y 1 A LYS 417 ? CG  ? C LYS 85  CG  
114 1 Y 1 A LYS 417 ? CD  ? C LYS 85  CD  
115 1 Y 1 A LYS 417 ? CE  ? C LYS 85  CE  
116 1 Y 1 A LYS 417 ? NZ  ? C LYS 85  NZ  
117 1 Y 1 A LEU 441 ? CG  ? C LEU 109 CG  
118 1 Y 1 A LEU 441 ? CD1 ? C LEU 109 CD1 
119 1 Y 1 A LEU 441 ? CD2 ? C LEU 109 CD2 
120 1 Y 1 A LYS 444 ? CG  ? C LYS 112 CG  
121 1 Y 1 A LYS 444 ? CD  ? C LYS 112 CD  
122 1 Y 1 A LYS 444 ? CE  ? C LYS 112 CE  
123 1 Y 1 A LYS 444 ? NZ  ? C LYS 112 NZ  
124 1 Y 1 A LYS 462 ? CG  ? C LYS 130 CG  
125 1 Y 1 A LYS 462 ? CD  ? C LYS 130 CD  
126 1 Y 1 A LYS 462 ? CE  ? C LYS 130 CE  
127 1 Y 1 A LYS 462 ? NZ  ? C LYS 130 NZ  
128 1 Y 1 A GLU 465 ? CG  ? C GLU 133 CG  
129 1 Y 1 A GLU 465 ? CD  ? C GLU 133 CD  
130 1 Y 1 A GLU 465 ? OE1 ? C GLU 133 OE1 
131 1 Y 1 A GLU 465 ? OE2 ? C GLU 133 OE2 
132 1 Y 1 A GLN 474 ? CG  ? C GLN 142 CG  
133 1 Y 1 A GLN 474 ? CD  ? C GLN 142 CD  
134 1 Y 1 A GLN 474 ? OE1 ? C GLN 142 OE1 
135 1 Y 1 A GLN 474 ? NE2 ? C GLN 142 NE2 
136 1 Y 1 A ASN 481 ? CG  ? C ASN 149 CG  
137 1 Y 1 A ASN 481 ? OD1 ? C ASN 149 OD1 
138 1 Y 1 A ASN 481 ? ND2 ? C ASN 149 ND2 
139 1 Y 1 A TYR 505 ? CG  ? C TYR 173 CG  
140 1 Y 1 A TYR 505 ? CD1 ? C TYR 173 CD1 
141 1 Y 1 A TYR 505 ? CD2 ? C TYR 173 CD2 
142 1 Y 1 A TYR 505 ? CE1 ? C TYR 173 CE1 
143 1 Y 1 A TYR 505 ? CE2 ? C TYR 173 CE2 
144 1 Y 1 A TYR 505 ? CZ  ? C TYR 173 CZ  
145 1 Y 1 A TYR 505 ? OH  ? C TYR 173 OH  
146 1 Y 1 D ARG 346 ? CG  ? D ARG 14  CG  
147 1 Y 1 D ARG 346 ? CD  ? D ARG 14  CD  
148 1 Y 1 D ARG 346 ? NE  ? D ARG 14  NE  
149 1 Y 1 D ARG 346 ? CZ  ? D ARG 14  CZ  
150 1 Y 1 D ARG 346 ? NH1 ? D ARG 14  NH1 
151 1 Y 1 D ARG 346 ? NH2 ? D ARG 14  NH2 
152 1 Y 1 D TYR 351 ? CG  ? D TYR 19  CG  
153 1 Y 1 D TYR 351 ? CD1 ? D TYR 19  CD1 
154 1 Y 1 D TYR 351 ? CD2 ? D TYR 19  CD2 
155 1 Y 1 D TYR 351 ? CE1 ? D TYR 19  CE1 
156 1 Y 1 D TYR 351 ? CE2 ? D TYR 19  CE2 
157 1 Y 1 D TYR 351 ? CZ  ? D TYR 19  CZ  
158 1 Y 1 D TYR 351 ? OH  ? D TYR 19  OH  
159 1 Y 1 D ASN 354 ? CG  ? D ASN 22  CG  
160 1 Y 1 D ASN 354 ? OD1 ? D ASN 22  OD1 
161 1 Y 1 D ASN 354 ? ND2 ? D ASN 22  ND2 
162 1 Y 1 D ASP 364 ? CG  ? D ASP 32  CG  
163 1 Y 1 D ASP 364 ? OD1 ? D ASP 32  OD1 
164 1 Y 1 D ASP 364 ? OD2 ? D ASP 32  OD2 
165 1 Y 1 D TYR 365 ? CG  ? D TYR 33  CG  
166 1 Y 1 D TYR 365 ? CD1 ? D TYR 33  CD1 
167 1 Y 1 D TYR 365 ? CD2 ? D TYR 33  CD2 
168 1 Y 1 D TYR 365 ? CE1 ? D TYR 33  CE1 
169 1 Y 1 D TYR 365 ? CE2 ? D TYR 33  CE2 
170 1 Y 1 D TYR 365 ? CZ  ? D TYR 33  CZ  
171 1 Y 1 D TYR 365 ? OH  ? D TYR 33  OH  
172 1 Y 1 D VAL 367 ? CG1 ? D VAL 35  CG1 
173 1 Y 1 D VAL 367 ? CG2 ? D VAL 35  CG2 
174 1 Y 1 D LEU 390 ? CG  ? D LEU 58  CG  
175 1 Y 1 D LEU 390 ? CD1 ? D LEU 58  CD1 
176 1 Y 1 D LEU 390 ? CD2 ? D LEU 58  CD2 
177 1 Y 1 D CYS 391 ? SG  ? D CYS 59  SG  
178 1 Y 1 D PHE 392 ? CG  ? D PHE 60  CG  
179 1 Y 1 D PHE 392 ? CD1 ? D PHE 60  CD1 
180 1 Y 1 D PHE 392 ? CD2 ? D PHE 60  CD2 
181 1 Y 1 D PHE 392 ? CE1 ? D PHE 60  CE1 
182 1 Y 1 D PHE 392 ? CE2 ? D PHE 60  CE2 
183 1 Y 1 D PHE 392 ? CZ  ? D PHE 60  CZ  
184 1 Y 1 D ASN 394 ? CG  ? D ASN 62  CG  
185 1 Y 1 D ASN 394 ? OD1 ? D ASN 62  OD1 
186 1 Y 1 D ASN 394 ? ND2 ? D ASN 62  ND2 
187 1 Y 1 D ASP 398 ? CG  ? D ASP 66  CG  
188 1 Y 1 D ASP 398 ? OD1 ? D ASP 66  OD1 
189 1 Y 1 D ASP 398 ? OD2 ? D ASP 66  OD2 
190 1 Y 1 D ARG 403 ? CG  ? D ARG 71  CG  
191 1 Y 1 D ARG 403 ? CD  ? D ARG 71  CD  
192 1 Y 1 D ARG 403 ? NE  ? D ARG 71  NE  
193 1 Y 1 D ARG 403 ? CZ  ? D ARG 71  CZ  
194 1 Y 1 D ARG 403 ? NH1 ? D ARG 71  NH1 
195 1 Y 1 D ARG 403 ? NH2 ? D ARG 71  NH2 
196 1 Y 1 D ASP 405 ? CG  ? D ASP 73  CG  
197 1 Y 1 D ASP 405 ? OD1 ? D ASP 73  OD1 
198 1 Y 1 D ASP 405 ? OD2 ? D ASP 73  OD2 
199 1 Y 1 D GLU 406 ? CG  ? D GLU 74  CG  
200 1 Y 1 D GLU 406 ? CD  ? D GLU 74  CD  
201 1 Y 1 D GLU 406 ? OE1 ? D GLU 74  OE1 
202 1 Y 1 D GLU 406 ? OE2 ? D GLU 74  OE2 
203 1 Y 1 D ARG 408 ? CG  ? D ARG 76  CG  
204 1 Y 1 D ARG 408 ? CD  ? D ARG 76  CD  
205 1 Y 1 D ARG 408 ? NE  ? D ARG 76  NE  
206 1 Y 1 D ARG 408 ? CZ  ? D ARG 76  CZ  
207 1 Y 1 D ARG 408 ? NH1 ? D ARG 76  NH1 
208 1 Y 1 D ARG 408 ? NH2 ? D ARG 76  NH2 
209 1 Y 1 D GLN 409 ? CG  ? D GLN 77  CG  
210 1 Y 1 D GLN 409 ? CD  ? D GLN 77  CD  
211 1 Y 1 D GLN 409 ? OE1 ? D GLN 77  OE1 
212 1 Y 1 D GLN 409 ? NE2 ? D GLN 77  NE2 
213 1 Y 1 D GLN 414 ? CG  ? D GLN 82  CG  
214 1 Y 1 D GLN 414 ? CD  ? D GLN 82  CD  
215 1 Y 1 D GLN 414 ? OE1 ? D GLN 82  OE1 
216 1 Y 1 D GLN 414 ? NE2 ? D GLN 82  NE2 
217 1 Y 1 D LYS 417 ? CG  ? D LYS 85  CG  
218 1 Y 1 D LYS 417 ? CD  ? D LYS 85  CD  
219 1 Y 1 D LYS 417 ? CE  ? D LYS 85  CE  
220 1 Y 1 D LYS 417 ? NZ  ? D LYS 85  NZ  
221 1 Y 1 D ILE 418 ? CG1 ? D ILE 86  CG1 
222 1 Y 1 D ILE 418 ? CG2 ? D ILE 86  CG2 
223 1 Y 1 D ILE 418 ? CD1 ? D ILE 86  CD1 
224 1 Y 1 D ASP 420 ? CG  ? D ASP 88  CG  
225 1 Y 1 D ASP 420 ? OD1 ? D ASP 88  OD1 
226 1 Y 1 D ASP 420 ? OD2 ? D ASP 88  OD2 
227 1 Y 1 D LYS 424 ? CG  ? D LYS 92  CG  
228 1 Y 1 D LYS 424 ? CD  ? D LYS 92  CD  
229 1 Y 1 D LYS 424 ? CE  ? D LYS 92  CE  
230 1 Y 1 D LYS 424 ? NZ  ? D LYS 92  NZ  
231 1 Y 1 D ASP 427 ? CG  ? D ASP 95  CG  
232 1 Y 1 D ASP 427 ? OD1 ? D ASP 95  OD1 
233 1 Y 1 D ASP 427 ? OD2 ? D ASP 95  OD2 
234 1 Y 1 D ASP 428 ? CG  ? D ASP 96  CG  
235 1 Y 1 D ASP 428 ? OD1 ? D ASP 96  OD1 
236 1 Y 1 D ASP 428 ? OD2 ? D ASP 96  OD2 
237 1 Y 1 D LYS 444 ? CG  ? D LYS 112 CG  
238 1 Y 1 D LYS 444 ? CD  ? D LYS 112 CD  
239 1 Y 1 D LYS 444 ? CE  ? D LYS 112 CE  
240 1 Y 1 D LYS 444 ? NZ  ? D LYS 112 NZ  
241 1 Y 1 D ASN 448 ? CG  ? D ASN 116 CG  
242 1 Y 1 D ASN 448 ? OD1 ? D ASN 116 OD1 
243 1 Y 1 D ASN 448 ? ND2 ? D ASN 116 ND2 
244 1 Y 1 D TYR 449 ? CG  ? D TYR 117 CG  
245 1 Y 1 D TYR 449 ? CD1 ? D TYR 117 CD1 
246 1 Y 1 D TYR 449 ? CD2 ? D TYR 117 CD2 
247 1 Y 1 D TYR 449 ? CE1 ? D TYR 117 CE1 
248 1 Y 1 D TYR 449 ? CE2 ? D TYR 117 CE2 
249 1 Y 1 D TYR 449 ? CZ  ? D TYR 117 CZ  
250 1 Y 1 D TYR 449 ? OH  ? D TYR 117 OH  
251 1 Y 1 D ASN 450 ? CG  ? D ASN 118 CG  
252 1 Y 1 D ASN 450 ? OD1 ? D ASN 118 OD1 
253 1 Y 1 D ASN 450 ? ND2 ? D ASN 118 ND2 
254 1 Y 1 D TYR 451 ? CG  ? D TYR 119 CG  
255 1 Y 1 D TYR 451 ? CD1 ? D TYR 119 CD1 
256 1 Y 1 D TYR 451 ? CD2 ? D TYR 119 CD2 
257 1 Y 1 D TYR 451 ? CE1 ? D TYR 119 CE1 
258 1 Y 1 D TYR 451 ? CE2 ? D TYR 119 CE2 
259 1 Y 1 D TYR 451 ? CZ  ? D TYR 119 CZ  
260 1 Y 1 D TYR 451 ? OH  ? D TYR 119 OH  
261 1 Y 1 D ARG 454 ? CG  ? D ARG 122 CG  
262 1 Y 1 D ARG 454 ? CD  ? D ARG 122 CD  
263 1 Y 1 D ARG 454 ? NE  ? D ARG 122 NE  
264 1 Y 1 D ARG 454 ? CZ  ? D ARG 122 CZ  
265 1 Y 1 D ARG 454 ? NH1 ? D ARG 122 NH1 
266 1 Y 1 D ARG 454 ? NH2 ? D ARG 122 NH2 
267 1 Y 1 D PHE 456 ? CG  ? D PHE 124 CG  
268 1 Y 1 D PHE 456 ? CD1 ? D PHE 124 CD1 
269 1 Y 1 D PHE 456 ? CD2 ? D PHE 124 CD2 
270 1 Y 1 D PHE 456 ? CE1 ? D PHE 124 CE1 
271 1 Y 1 D PHE 456 ? CE2 ? D PHE 124 CE2 
272 1 Y 1 D PHE 456 ? CZ  ? D PHE 124 CZ  
273 1 Y 1 D ARG 457 ? CG  ? D ARG 125 CG  
274 1 Y 1 D ARG 457 ? CD  ? D ARG 125 CD  
275 1 Y 1 D ARG 457 ? NE  ? D ARG 125 NE  
276 1 Y 1 D ARG 457 ? CZ  ? D ARG 125 CZ  
277 1 Y 1 D ARG 457 ? NH1 ? D ARG 125 NH1 
278 1 Y 1 D ARG 457 ? NH2 ? D ARG 125 NH2 
279 1 Y 1 D LYS 458 ? CG  ? D LYS 126 CG  
280 1 Y 1 D LYS 458 ? CD  ? D LYS 126 CD  
281 1 Y 1 D LYS 458 ? CE  ? D LYS 126 CE  
282 1 Y 1 D LYS 458 ? NZ  ? D LYS 126 NZ  
283 1 Y 1 D SER 459 ? OG  ? D SER 127 OG  
284 1 Y 1 D ASN 460 ? CG  ? D ASN 128 CG  
285 1 Y 1 D ASN 460 ? OD1 ? D ASN 128 OD1 
286 1 Y 1 D ASN 460 ? ND2 ? D ASN 128 ND2 
287 1 Y 1 D LYS 462 ? CG  ? D LYS 130 CG  
288 1 Y 1 D LYS 462 ? CD  ? D LYS 130 CD  
289 1 Y 1 D LYS 462 ? CE  ? D LYS 130 CE  
290 1 Y 1 D LYS 462 ? NZ  ? D LYS 130 NZ  
291 1 Y 1 D GLN 498 ? CG  ? D GLN 166 CG  
292 1 Y 1 D GLN 498 ? CD  ? D GLN 166 CD  
293 1 Y 1 D GLN 498 ? OE1 ? D GLN 166 OE1 
294 1 Y 1 D GLN 498 ? NE2 ? D GLN 166 NE2 
295 1 Y 1 D THR 500 ? OG1 ? D THR 168 OG1 
296 1 Y 1 D THR 500 ? CG2 ? D THR 168 CG2 
297 1 Y 1 D TYR 505 ? CG  ? D TYR 173 CG  
298 1 Y 1 D TYR 505 ? CD1 ? D TYR 173 CD1 
299 1 Y 1 D TYR 505 ? CD2 ? D TYR 173 CD2 
300 1 Y 1 D TYR 505 ? CE1 ? D TYR 173 CE1 
301 1 Y 1 D TYR 505 ? CE2 ? D TYR 173 CE2 
302 1 Y 1 D TYR 505 ? CZ  ? D TYR 173 CZ  
303 1 Y 1 D TYR 505 ? OH  ? D TYR 173 OH  
304 1 Y 1 D GLU 516 ? CG  ? D GLU 184 CG  
305 1 Y 1 D GLU 516 ? CD  ? D GLU 184 CD  
306 1 Y 1 D GLU 516 ? OE1 ? D GLU 184 OE1 
307 1 Y 1 D GLU 516 ? OE2 ? D GLU 184 OE2 
308 1 Y 1 D LEU 517 ? CG  ? D LEU 185 CG  
309 1 Y 1 D LEU 517 ? CD1 ? D LEU 185 CD1 
310 1 Y 1 D LEU 517 ? CD2 ? D LEU 185 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9J66 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9J66 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9J66 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9J66 
_struct.title                        
;Cryo-EM structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment CAV-C65 (local refinement)
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9J66 
_struct_keywords.text            
'SARS-COV-2, spike glycoprotein, neutralizing antibody, viral protein-immune system complex (local refinement), VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9J66        9J66   ? 1 ? 1   
2 PDB 9J66        9J66   ? 2 ? 1   
3 UNP SPIKE_SARS2 P0DTC2 ? 3 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9J66 B 1 ? 231 ? 9J66   1   ? 231 ? 1   231 
2 2 9J66 C 1 ? 214 ? 9J66   1   ? 214 ? 1   214 
3 3 9J66 A 1 ? 195 ? P0DTC2 333 ? 527 ? 333 527 
4 3 9J66 D 1 ? 195 ? P0DTC2 333 ? 527 ? 333 527 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO C 5   ? VAL C 9   ? PRO A 337 VAL A 341 5 ? 5 
HELX_P HELX_P2  AA2 SER C 17  ? TRP C 21  ? SER A 349 TRP A 353 5 ? 5 
HELX_P HELX_P3  AA3 TYR C 33  ? ASN C 38  ? TYR A 365 ASN A 370 1 ? 6 
HELX_P HELX_P4  AA4 SER C 51  ? LEU C 58  ? SER A 383 LEU A 390 5 ? 8 
HELX_P HELX_P5  AA5 GLY C 72  ? ARG C 76  ? GLY A 404 ARG A 408 1 ? 5 
HELX_P HELX_P6  AA6 LYS C 85  ? ASN C 90  ? LYS A 417 ASN A 422 1 ? 6 
HELX_P HELX_P7  AA7 GLY C 170 ? TYR C 173 ? GLY A 502 TYR A 505 5 ? 4 
HELX_P HELX_P8  AA8 PRO D 5   ? PHE D 10  ? PRO D 337 PHE D 342 1 ? 6 
HELX_P HELX_P9  AA9 ASP D 73  ? ILE D 78  ? ASP D 405 ILE D 410 5 ? 6 
HELX_P HELX_P10 AB1 GLY D 84  ? TYR D 89  ? GLY D 416 TYR D 421 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22  SG ? ? ? 1_555 A CYS 96  SG ? ? B CYS 22  B CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? B CYS 23  SG ? ? ? 1_555 B CYS 88  SG ? ? C CYS 23  C CYS 88  1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf3 disulf ? ? C CYS 4   SG ? ? ? 1_555 C CYS 29  SG ? ? A CYS 336 A CYS 361 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4 disulf ? ? C CYS 47  SG ? ? ? 1_555 C CYS 100 SG ? ? A CYS 379 A CYS 432 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf5 disulf ? ? C CYS 59  SG ? ? ? 1_555 C CYS 193 SG ? ? A CYS 391 A CYS 525 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf6 disulf ? ? C CYS 148 SG ? ? ? 1_555 C CYS 156 SG ? ? A CYS 480 A CYS 488 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf7 disulf ? ? D CYS 4   SG ? ? ? 1_555 D CYS 29  SG ? ? D CYS 336 D CYS 361 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf8 disulf ? ? D CYS 47  SG ? ? ? 1_555 D CYS 100 SG ? ? D CYS 379 D CYS 432 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 22  ? CYS A 96  ? CYS B 22  ? 1_555 CYS B 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 23  ? CYS B 88  ? CYS C 23  ? 1_555 CYS C 88  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS C 4   ? CYS C 29  ? CYS A 336 ? 1_555 CYS A 361 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS C 47  ? CYS C 100 ? CYS A 379 ? 1_555 CYS A 432 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS C 59  ? CYS C 193 ? CYS A 391 ? 1_555 CYS A 525 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS C 148 ? CYS C 156 ? CYS A 480 ? 1_555 CYS A 488 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7 CYS D 4   ? CYS D 29  ? CYS D 336 ? 1_555 CYS D 361 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8 CYS D 47  ? CYS D 100 ? CYS D 379 ? 1_555 CYS D 432 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 3 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 5 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? GLN A 6   ? GLN B 3   GLN B 6   
AA1 2 SER A 21  ? SER A 25  ? SER B 21  SER B 25  
AA1 3 THR A 78  ? LEU A 86  ? THR B 78  LEU B 86  
AA1 4 SER A 16  ? VAL A 18  ? SER B 16  VAL B 18  
AA2 1 GLN A 3   ? GLN A 6   ? GLN B 3   GLN B 6   
AA2 2 SER A 21  ? SER A 25  ? SER B 21  SER B 25  
AA2 3 THR A 78  ? LEU A 86  ? THR B 78  LEU B 86  
AA2 4 VAL A 68  ? ASP A 73  ? VAL B 68  ASP B 73  
AA3 1 LEU A 45  ? ARG A 50  ? LEU B 45  ARG B 50  
AA3 2 TYR A 32  ? GLN A 39  ? TYR B 32  GLN B 39  
AA3 3 ALA A 92  ? GLU A 102 ? ALA B 92  GLU B 102 
AA3 4 TYR A 112 ? TRP A 113 ? TYR B 112 TRP B 113 
AA4 1 THR A 105 ? GLU A 106 ? THR B 105 GLU B 106 
AA4 2 ALA A 92  ? GLU A 102 ? ALA B 92  GLU B 102 
AA4 3 THR A 117 ? VAL A 119 ? THR B 117 VAL B 119 
AA5 1 VAL B 19  ? ARG B 24  ? VAL C 19  ARG C 24  
AA5 2 ASP B 70  ? ILE B 75  ? ASP C 70  ILE C 75  
AA5 3 PHE B 62  ? SER B 67  ? PHE C 62  SER C 67  
AA6 1 SER B 53  ? LEU B 54  ? SER C 53  LEU C 54  
AA6 2 ILE B 48  ? TYR B 49  ? ILE C 48  TYR C 49  
AA6 3 ALA B 34  ? TRP B 35  ? ALA C 34  TRP C 35  
AA6 4 CYS B 88  ? GLN B 89  ? CYS C 88  GLN C 89  
AA7 1 THR B 85  ? TYR B 86  ? THR C 85  TYR C 86  
AA7 2 THR B 102 ? LYS B 103 ? THR C 102 LYS C 103 
AA8 1 ASN C 22  ? ILE C 26  ? ASN A 354 ILE A 358 
AA8 2 VAL C 63  ? ARG C 71  ? VAL A 395 ARG A 403 
AA8 3 PRO C 175 ? PHE C 183 ? PRO A 507 PHE A 515 
AA8 4 GLY C 99  ? ASN C 105 ? GLY A 431 ASN A 437 
AA8 5 THR C 44  ? CYS C 47  ? THR A 376 CYS A 379 
AA9 1 LEU C 120 ? ARG C 122 ? LEU A 452 ARG A 454 
AA9 2 LEU C 160 ? SER C 162 ? LEU A 492 SER A 494 
AB1 1 TYR C 141 ? GLN C 142 ? TYR A 473 GLN A 474 
AB1 2 CYS C 156 ? TYR C 157 ? CYS A 488 TYR A 489 
AB2 1 VAL D 63  ? ARG D 71  ? VAL D 395 ARG D 403 
AB2 2 PRO D 175 ? PHE D 183 ? PRO D 507 PHE D 515 
AB2 3 CYS D 100 ? ASN D 105 ? CYS D 432 ASN D 437 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 5   ? N VAL B 5   O LYS A 23  ? O LYS B 23  
AA1 2 3 N CYS A 22  ? N CYS B 22  O ALA A 79  ? O ALA B 79  
AA1 3 4 O LEU A 86  ? O LEU B 86  N SER A 16  ? N SER B 16  
AA2 1 2 N VAL A 5   ? N VAL B 5   O LYS A 23  ? O LYS B 23  
AA2 2 3 N CYS A 22  ? N CYS B 22  O ALA A 79  ? O ALA B 79  
AA2 3 4 O TYR A 80  ? O TYR B 80  N THR A 71  ? N THR B 71  
AA3 1 2 O GLU A 46  ? O GLU B 46  N ARG A 38  ? N ARG B 38  
AA3 2 3 N VAL A 37  ? N VAL B 37  O TYR A 95  ? O TYR B 95  
AA3 3 4 N ARG A 98  ? N ARG B 98  O TYR A 112 ? O TYR B 112 
AA4 1 2 O THR A 105 ? O THR B 105 N GLU A 102 ? N GLU B 102 
AA4 2 3 N TYR A 94  ? N TYR B 94  O THR A 117 ? O THR B 117 
AA5 1 2 N ILE B 21  ? N ILE C 21  O LEU B 73  ? O LEU C 73  
AA5 2 3 O THR B 74  ? O THR C 74  N SER B 63  ? N SER C 63  
AA6 1 2 O SER B 53  ? O SER C 53  N TYR B 49  ? N TYR C 49  
AA6 2 3 O ILE B 48  ? O ILE C 48  N TRP B 35  ? N TRP C 35  
AA6 3 4 N ALA B 34  ? N ALA C 34  O GLN B 89  ? O GLN C 89  
AA7 1 2 N TYR B 86  ? N TYR C 86  O THR B 102 ? O THR C 102 
AA8 1 2 N ILE C 26  ? N ILE A 358 O VAL C 63  ? O VAL A 395 
AA8 2 3 N PHE C 68  ? N PHE A 400 O VAL C 178 ? O VAL A 510 
AA8 3 4 O LEU C 181 ? O LEU A 513 N CYS C 100 ? N CYS A 432 
AA8 4 5 O ALA C 103 ? O ALA A 435 N THR C 44  ? N THR A 376 
AA9 1 2 N TYR C 121 ? N TYR A 453 O GLN C 161 ? O GLN A 493 
AB1 1 2 N TYR C 141 ? N TYR A 473 O TYR C 157 ? O TYR A 489 
AB2 1 2 N ILE D 70  ? N ILE D 402 O TYR D 176 ? O TYR D 508 
AB2 2 3 O VAL D 179 ? O VAL D 511 N ILE D 102 ? N ILE D 434 
# 
_pdbx_entry_details.entry_id                   9J66 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER B 88  ? ? 60.24   -126.86 
2  1 MET B 103 ? ? 57.13   -95.41  
3  1 SER C 30  ? ? 56.29   -126.34 
4  1 ALA C 51  ? ? 67.83   -4.08   
5  1 PHE C 83  ? ? -101.77 64.25   
6  1 PRO C 95  ? ? -67.48  79.15   
7  1 VAL A 341 ? ? -108.62 -61.78  
8  1 ASN A 388 ? ? -85.68  47.54   
9  1 THR A 523 ? ? -140.42 18.12   
10 1 ASN D 360 ? ? 38.29   54.39   
11 1 CYS D 361 ? ? -126.29 -169.39 
12 1 SER D 366 ? ? -91.75  53.54   
13 1 TYR D 449 ? ? -163.00 -169.01 
14 1 PHE D 456 ? ? -140.18 14.85   
15 1 LYS D 458 ? ? 50.57   -110.57 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9J66 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9J66 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.55 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               579375 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 
'complex of the SARS-CoV-2 S 6P trimer with the human neutralizing antibody Fab fragment CAV-C65' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9J66 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'JEOL CRYO ARM 300' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9J66 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9J66 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B SER 125 ? A SER 125 
2   1 Y 1 B VAL 126 ? A VAL 126 
3   1 Y 1 B ARG 127 ? A ARG 127 
4   1 Y 1 B SER 128 ? A SER 128 
5   1 Y 1 B THR 129 ? A THR 129 
6   1 Y 1 B LYS 130 ? A LYS 130 
7   1 Y 1 B GLY 131 ? A GLY 131 
8   1 Y 1 B PRO 132 ? A PRO 132 
9   1 Y 1 B SER 133 ? A SER 133 
10  1 Y 1 B VAL 134 ? A VAL 134 
11  1 Y 1 B PHE 135 ? A PHE 135 
12  1 Y 1 B PRO 136 ? A PRO 136 
13  1 Y 1 B LEU 137 ? A LEU 137 
14  1 Y 1 B ALA 138 ? A ALA 138 
15  1 Y 1 B PRO 139 ? A PRO 139 
16  1 Y 1 B SER 140 ? A SER 140 
17  1 Y 1 B SER 141 ? A SER 141 
18  1 Y 1 B LYS 142 ? A LYS 142 
19  1 Y 1 B SER 143 ? A SER 143 
20  1 Y 1 B THR 144 ? A THR 144 
21  1 Y 1 B SER 145 ? A SER 145 
22  1 Y 1 B GLY 146 ? A GLY 146 
23  1 Y 1 B GLY 147 ? A GLY 147 
24  1 Y 1 B THR 148 ? A THR 148 
25  1 Y 1 B ALA 149 ? A ALA 149 
26  1 Y 1 B ALA 150 ? A ALA 150 
27  1 Y 1 B LEU 151 ? A LEU 151 
28  1 Y 1 B GLY 152 ? A GLY 152 
29  1 Y 1 B CYS 153 ? A CYS 153 
30  1 Y 1 B LEU 154 ? A LEU 154 
31  1 Y 1 B VAL 155 ? A VAL 155 
32  1 Y 1 B LYS 156 ? A LYS 156 
33  1 Y 1 B ASP 157 ? A ASP 157 
34  1 Y 1 B TYR 158 ? A TYR 158 
35  1 Y 1 B PHE 159 ? A PHE 159 
36  1 Y 1 B PRO 160 ? A PRO 160 
37  1 Y 1 B GLU 161 ? A GLU 161 
38  1 Y 1 B PRO 162 ? A PRO 162 
39  1 Y 1 B VAL 163 ? A VAL 163 
40  1 Y 1 B THR 164 ? A THR 164 
41  1 Y 1 B VAL 165 ? A VAL 165 
42  1 Y 1 B SER 166 ? A SER 166 
43  1 Y 1 B TRP 167 ? A TRP 167 
44  1 Y 1 B ASN 168 ? A ASN 168 
45  1 Y 1 B SER 169 ? A SER 169 
46  1 Y 1 B GLY 170 ? A GLY 170 
47  1 Y 1 B ALA 171 ? A ALA 171 
48  1 Y 1 B LEU 172 ? A LEU 172 
49  1 Y 1 B THR 173 ? A THR 173 
50  1 Y 1 B SER 174 ? A SER 174 
51  1 Y 1 B GLY 175 ? A GLY 175 
52  1 Y 1 B VAL 176 ? A VAL 176 
53  1 Y 1 B HIS 177 ? A HIS 177 
54  1 Y 1 B THR 178 ? A THR 178 
55  1 Y 1 B PHE 179 ? A PHE 179 
56  1 Y 1 B PRO 180 ? A PRO 180 
57  1 Y 1 B ALA 181 ? A ALA 181 
58  1 Y 1 B VAL 182 ? A VAL 182 
59  1 Y 1 B LEU 183 ? A LEU 183 
60  1 Y 1 B GLN 184 ? A GLN 184 
61  1 Y 1 B SER 185 ? A SER 185 
62  1 Y 1 B SER 186 ? A SER 186 
63  1 Y 1 B GLY 187 ? A GLY 187 
64  1 Y 1 B LEU 188 ? A LEU 188 
65  1 Y 1 B TYR 189 ? A TYR 189 
66  1 Y 1 B SER 190 ? A SER 190 
67  1 Y 1 B LEU 191 ? A LEU 191 
68  1 Y 1 B SER 192 ? A SER 192 
69  1 Y 1 B SER 193 ? A SER 193 
70  1 Y 1 B VAL 194 ? A VAL 194 
71  1 Y 1 B VAL 195 ? A VAL 195 
72  1 Y 1 B THR 196 ? A THR 196 
73  1 Y 1 B VAL 197 ? A VAL 197 
74  1 Y 1 B PRO 198 ? A PRO 198 
75  1 Y 1 B SER 199 ? A SER 199 
76  1 Y 1 B SER 200 ? A SER 200 
77  1 Y 1 B SER 201 ? A SER 201 
78  1 Y 1 B LEU 202 ? A LEU 202 
79  1 Y 1 B GLY 203 ? A GLY 203 
80  1 Y 1 B THR 204 ? A THR 204 
81  1 Y 1 B GLN 205 ? A GLN 205 
82  1 Y 1 B THR 206 ? A THR 206 
83  1 Y 1 B TYR 207 ? A TYR 207 
84  1 Y 1 B ILE 208 ? A ILE 208 
85  1 Y 1 B CYS 209 ? A CYS 209 
86  1 Y 1 B ASN 210 ? A ASN 210 
87  1 Y 1 B VAL 211 ? A VAL 211 
88  1 Y 1 B ASN 212 ? A ASN 212 
89  1 Y 1 B HIS 213 ? A HIS 213 
90  1 Y 1 B LYS 214 ? A LYS 214 
91  1 Y 1 B PRO 215 ? A PRO 215 
92  1 Y 1 B SER 216 ? A SER 216 
93  1 Y 1 B ASN 217 ? A ASN 217 
94  1 Y 1 B THR 218 ? A THR 218 
95  1 Y 1 B LYS 219 ? A LYS 219 
96  1 Y 1 B VAL 220 ? A VAL 220 
97  1 Y 1 B ASP 221 ? A ASP 221 
98  1 Y 1 B LYS 222 ? A LYS 222 
99  1 Y 1 B LYS 223 ? A LYS 223 
100 1 Y 1 B VAL 224 ? A VAL 224 
101 1 Y 1 B GLU 225 ? A GLU 225 
102 1 Y 1 B PRO 226 ? A PRO 226 
103 1 Y 1 B LYS 227 ? A LYS 227 
104 1 Y 1 B SER 228 ? A SER 228 
105 1 Y 1 B CYS 229 ? A CYS 229 
106 1 Y 1 B SER 230 ? A SER 230 
107 1 Y 1 B GLY 231 ? A GLY 231 
108 1 Y 1 C ARG 108 ? B ARG 108 
109 1 Y 1 C THR 109 ? B THR 109 
110 1 Y 1 C VAL 110 ? B VAL 110 
111 1 Y 1 C ALA 111 ? B ALA 111 
112 1 Y 1 C ALA 112 ? B ALA 112 
113 1 Y 1 C PRO 113 ? B PRO 113 
114 1 Y 1 C SER 114 ? B SER 114 
115 1 Y 1 C VAL 115 ? B VAL 115 
116 1 Y 1 C PHE 116 ? B PHE 116 
117 1 Y 1 C ILE 117 ? B ILE 117 
118 1 Y 1 C PHE 118 ? B PHE 118 
119 1 Y 1 C PRO 119 ? B PRO 119 
120 1 Y 1 C PRO 120 ? B PRO 120 
121 1 Y 1 C SER 121 ? B SER 121 
122 1 Y 1 C ASP 122 ? B ASP 122 
123 1 Y 1 C GLU 123 ? B GLU 123 
124 1 Y 1 C GLN 124 ? B GLN 124 
125 1 Y 1 C LEU 125 ? B LEU 125 
126 1 Y 1 C LYS 126 ? B LYS 126 
127 1 Y 1 C SER 127 ? B SER 127 
128 1 Y 1 C GLY 128 ? B GLY 128 
129 1 Y 1 C THR 129 ? B THR 129 
130 1 Y 1 C ALA 130 ? B ALA 130 
131 1 Y 1 C SER 131 ? B SER 131 
132 1 Y 1 C VAL 132 ? B VAL 132 
133 1 Y 1 C VAL 133 ? B VAL 133 
134 1 Y 1 C CYS 134 ? B CYS 134 
135 1 Y 1 C LEU 135 ? B LEU 135 
136 1 Y 1 C LEU 136 ? B LEU 136 
137 1 Y 1 C ASN 137 ? B ASN 137 
138 1 Y 1 C ASN 138 ? B ASN 138 
139 1 Y 1 C PHE 139 ? B PHE 139 
140 1 Y 1 C TYR 140 ? B TYR 140 
141 1 Y 1 C PRO 141 ? B PRO 141 
142 1 Y 1 C ARG 142 ? B ARG 142 
143 1 Y 1 C GLU 143 ? B GLU 143 
144 1 Y 1 C ALA 144 ? B ALA 144 
145 1 Y 1 C LYS 145 ? B LYS 145 
146 1 Y 1 C VAL 146 ? B VAL 146 
147 1 Y 1 C GLN 147 ? B GLN 147 
148 1 Y 1 C TRP 148 ? B TRP 148 
149 1 Y 1 C LYS 149 ? B LYS 149 
150 1 Y 1 C VAL 150 ? B VAL 150 
151 1 Y 1 C ASP 151 ? B ASP 151 
152 1 Y 1 C ASN 152 ? B ASN 152 
153 1 Y 1 C ALA 153 ? B ALA 153 
154 1 Y 1 C LEU 154 ? B LEU 154 
155 1 Y 1 C GLN 155 ? B GLN 155 
156 1 Y 1 C SER 156 ? B SER 156 
157 1 Y 1 C GLY 157 ? B GLY 157 
158 1 Y 1 C ASN 158 ? B ASN 158 
159 1 Y 1 C SER 159 ? B SER 159 
160 1 Y 1 C GLN 160 ? B GLN 160 
161 1 Y 1 C GLU 161 ? B GLU 161 
162 1 Y 1 C SER 162 ? B SER 162 
163 1 Y 1 C VAL 163 ? B VAL 163 
164 1 Y 1 C THR 164 ? B THR 164 
165 1 Y 1 C GLU 165 ? B GLU 165 
166 1 Y 1 C GLN 166 ? B GLN 166 
167 1 Y 1 C ASP 167 ? B ASP 167 
168 1 Y 1 C SER 168 ? B SER 168 
169 1 Y 1 C LYS 169 ? B LYS 169 
170 1 Y 1 C ASP 170 ? B ASP 170 
171 1 Y 1 C SER 171 ? B SER 171 
172 1 Y 1 C THR 172 ? B THR 172 
173 1 Y 1 C TYR 173 ? B TYR 173 
174 1 Y 1 C SER 174 ? B SER 174 
175 1 Y 1 C LEU 175 ? B LEU 175 
176 1 Y 1 C SER 176 ? B SER 176 
177 1 Y 1 C SER 177 ? B SER 177 
178 1 Y 1 C THR 178 ? B THR 178 
179 1 Y 1 C LEU 179 ? B LEU 179 
180 1 Y 1 C THR 180 ? B THR 180 
181 1 Y 1 C LEU 181 ? B LEU 181 
182 1 Y 1 C SER 182 ? B SER 182 
183 1 Y 1 C LYS 183 ? B LYS 183 
184 1 Y 1 C ALA 184 ? B ALA 184 
185 1 Y 1 C ASP 185 ? B ASP 185 
186 1 Y 1 C TYR 186 ? B TYR 186 
187 1 Y 1 C GLU 187 ? B GLU 187 
188 1 Y 1 C LYS 188 ? B LYS 188 
189 1 Y 1 C HIS 189 ? B HIS 189 
190 1 Y 1 C LYS 190 ? B LYS 190 
191 1 Y 1 C VAL 191 ? B VAL 191 
192 1 Y 1 C TYR 192 ? B TYR 192 
193 1 Y 1 C ALA 193 ? B ALA 193 
194 1 Y 1 C CYS 194 ? B CYS 194 
195 1 Y 1 C GLU 195 ? B GLU 195 
196 1 Y 1 C VAL 196 ? B VAL 196 
197 1 Y 1 C THR 197 ? B THR 197 
198 1 Y 1 C HIS 198 ? B HIS 198 
199 1 Y 1 C GLN 199 ? B GLN 199 
200 1 Y 1 C GLY 200 ? B GLY 200 
201 1 Y 1 C LEU 201 ? B LEU 201 
202 1 Y 1 C SER 202 ? B SER 202 
203 1 Y 1 C SER 203 ? B SER 203 
204 1 Y 1 C PRO 204 ? B PRO 204 
205 1 Y 1 C VAL 205 ? B VAL 205 
206 1 Y 1 C THR 206 ? B THR 206 
207 1 Y 1 C LYS 207 ? B LYS 207 
208 1 Y 1 C SER 208 ? B SER 208 
209 1 Y 1 C PHE 209 ? B PHE 209 
210 1 Y 1 C ASN 210 ? B ASN 210 
211 1 Y 1 C ARG 211 ? B ARG 211 
212 1 Y 1 C GLY 212 ? B GLY 212 
213 1 Y 1 C GLU 213 ? B GLU 213 
214 1 Y 1 C CYS 214 ? B CYS 214 
215 1 Y 1 A LEU 518 ? C LEU 186 
216 1 Y 1 A HIS 519 ? C HIS 187 
217 1 Y 1 D LYS 356 ? D LYS 24  
218 1 Y 1 D ARG 357 ? D ARG 25  
219 1 Y 1 D ILE 358 ? D ILE 26  
220 1 Y 1 D LEU 368 ? D LEU 36  
221 1 Y 1 D TYR 369 ? D TYR 37  
222 1 Y 1 D ASN 370 ? D ASN 38  
223 1 Y 1 D SER 371 ? D SER 39  
224 1 Y 1 D ALA 372 ? D ALA 40  
225 1 Y 1 D SER 373 ? D SER 41  
226 1 Y 1 D PHE 374 ? D PHE 42  
227 1 Y 1 D LYS 386 ? D LYS 54  
228 1 Y 1 D LEU 387 ? D LEU 55  
229 1 Y 1 D ASN 388 ? D ASN 56  
230 1 Y 1 D ASP 389 ? D ASP 57  
231 1 Y 1 D VAL 445 ? D VAL 113 
232 1 Y 1 D GLY 446 ? D GLY 114 
233 1 Y 1 D PHE 464 ? D PHE 132 
234 1 Y 1 D GLU 465 ? D GLU 133 
235 1 Y 1 D ARG 466 ? D ARG 134 
236 1 Y 1 D ASP 467 ? D ASP 135 
237 1 Y 1 D ILE 468 ? D ILE 136 
238 1 Y 1 D SER 469 ? D SER 137 
239 1 Y 1 D THR 470 ? D THR 138 
240 1 Y 1 D GLU 471 ? D GLU 139 
241 1 Y 1 D ILE 472 ? D ILE 140 
242 1 Y 1 D TYR 473 ? D TYR 141 
243 1 Y 1 D GLN 474 ? D GLN 142 
244 1 Y 1 D ALA 475 ? D ALA 143 
245 1 Y 1 D GLY 476 ? D GLY 144 
246 1 Y 1 D SER 477 ? D SER 145 
247 1 Y 1 D THR 478 ? D THR 146 
248 1 Y 1 D PRO 479 ? D PRO 147 
249 1 Y 1 D CYS 480 ? D CYS 148 
250 1 Y 1 D ASN 481 ? D ASN 149 
251 1 Y 1 D GLY 482 ? D GLY 150 
252 1 Y 1 D VAL 483 ? D VAL 151 
253 1 Y 1 D GLU 484 ? D GLU 152 
254 1 Y 1 D GLY 485 ? D GLY 153 
255 1 Y 1 D PHE 486 ? D PHE 154 
256 1 Y 1 D ASN 487 ? D ASN 155 
257 1 Y 1 D CYS 488 ? D CYS 156 
258 1 Y 1 D TYR 489 ? D TYR 157 
259 1 Y 1 D PHE 490 ? D PHE 158 
260 1 Y 1 D PRO 491 ? D PRO 159 
261 1 Y 1 D LEU 492 ? D LEU 160 
262 1 Y 1 D GLN 493 ? D GLN 161 
263 1 Y 1 D SER 494 ? D SER 162 
264 1 Y 1 D TYR 495 ? D TYR 163 
265 1 Y 1 D GLY 496 ? D GLY 164 
266 1 Y 1 D PHE 497 ? D PHE 165 
267 1 Y 1 D LEU 518 ? D LEU 186 
268 1 Y 1 D HIS 519 ? D HIS 187 
269 1 Y 1 D ALA 520 ? D ALA 188 
270 1 Y 1 D PRO 521 ? D PRO 189 
271 1 Y 1 D ALA 522 ? D ALA 190 
272 1 Y 1 D THR 523 ? D THR 191 
273 1 Y 1 D VAL 524 ? D VAL 192 
274 1 Y 1 D CYS 525 ? D CYS 193 
275 1 Y 1 D GLY 526 ? D GLY 194 
276 1 Y 1 D PRO 527 ? D PRO 195 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-15 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9J66 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              
;Cryo-EM structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment CAV-C65 (local refinement)
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2697049 
_em_entity_assembly_naturalsource.organism             'Severe acute respiratory syndrome coronavirus 2' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministry of Science and Technology (MoST, China)'    China 2022YFC2303300 1 
'National Natural Science Foundation of China (NSFC)' China U23A20147      2 
# 
_atom_sites.entry_id                    9J66 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLN A 1 1   ? 185.187 215.906 128.830 1.00 64.71  ? 1   GLN B N   1 
ATOM 2    C CA  . GLN A 1 1   ? 185.121 216.181 127.399 1.00 64.71  ? 1   GLN B CA  1 
ATOM 3    C C   . GLN A 1 1   ? 184.740 214.930 126.618 1.00 64.71  ? 1   GLN B C   1 
ATOM 4    O O   . GLN A 1 1   ? 185.480 214.488 125.739 1.00 64.71  ? 1   GLN B O   1 
ATOM 5    C CB  . GLN A 1 1   ? 186.459 216.728 126.896 1.00 64.71  ? 1   GLN B CB  1 
ATOM 6    N N   . VAL A 1 2   ? 183.579 214.361 126.945 1.00 59.57  ? 2   VAL B N   1 
ATOM 7    C CA  . VAL A 1 2   ? 183.125 213.151 126.271 1.00 59.57  ? 2   VAL B CA  1 
ATOM 8    C C   . VAL A 1 2   ? 182.665 213.481 124.857 1.00 59.57  ? 2   VAL B C   1 
ATOM 9    O O   . VAL A 1 2   ? 181.926 214.448 124.625 1.00 59.57  ? 2   VAL B O   1 
ATOM 10   C CB  . VAL A 1 2   ? 182.019 212.460 127.089 1.00 59.57  ? 2   VAL B CB  1 
ATOM 11   C CG1 . VAL A 1 2   ? 180.793 213.337 127.201 1.00 59.57  ? 2   VAL B CG1 1 
ATOM 12   C CG2 . VAL A 1 2   ? 181.650 211.131 126.455 1.00 59.57  ? 2   VAL B CG2 1 
ATOM 13   N N   . GLN A 1 3   ? 183.134 212.693 123.896 1.00 61.44  ? 3   GLN B N   1 
ATOM 14   C CA  . GLN A 1 3   ? 182.773 212.853 122.497 1.00 61.44  ? 3   GLN B CA  1 
ATOM 15   C C   . GLN A 1 3   ? 182.317 211.513 121.945 1.00 61.44  ? 3   GLN B C   1 
ATOM 16   O O   . GLN A 1 3   ? 182.851 210.465 122.318 1.00 61.44  ? 3   GLN B O   1 
ATOM 17   C CB  . GLN A 1 3   ? 183.951 213.394 121.673 1.00 61.44  ? 3   GLN B CB  1 
ATOM 18   C CG  . GLN A 1 3   ? 184.331 214.828 122.006 1.00 61.44  ? 3   GLN B CG  1 
ATOM 19   C CD  . GLN A 1 3   ? 185.553 215.303 121.245 1.00 61.44  ? 3   GLN B CD  1 
ATOM 20   O OE1 . GLN A 1 3   ? 186.168 214.543 120.497 1.00 61.44  ? 3   GLN B OE1 1 
ATOM 21   N NE2 . GLN A 1 3   ? 185.907 216.570 121.427 1.00 61.44  ? 3   GLN B NE2 1 
ATOM 22   N N   . LEU A 1 4   ? 181.325 211.551 121.062 1.00 52.14  ? 4   LEU B N   1 
ATOM 23   C CA  . LEU A 1 4   ? 180.740 210.351 120.482 1.00 52.14  ? 4   LEU B CA  1 
ATOM 24   C C   . LEU A 1 4   ? 181.041 210.319 118.992 1.00 52.14  ? 4   LEU B C   1 
ATOM 25   O O   . LEU A 1 4   ? 180.801 211.303 118.285 1.00 52.14  ? 4   LEU B O   1 
ATOM 26   C CB  . LEU A 1 4   ? 179.229 210.305 120.729 1.00 52.14  ? 4   LEU B CB  1 
ATOM 27   C CG  . LEU A 1 4   ? 178.759 209.679 122.047 1.00 52.14  ? 4   LEU B CG  1 
ATOM 28   C CD1 . LEU A 1 4   ? 179.261 210.450 123.257 1.00 52.14  ? 4   LEU B CD1 1 
ATOM 29   C CD2 . LEU A 1 4   ? 177.246 209.592 122.075 1.00 52.14  ? 4   LEU B CD2 1 
ATOM 30   N N   . VAL A 1 5   ? 181.569 209.193 118.518 1.00 53.14  ? 5   VAL B N   1 
ATOM 31   C CA  . VAL A 1 5   ? 181.976 209.031 117.127 1.00 53.14  ? 5   VAL B CA  1 
ATOM 32   C C   . VAL A 1 5   ? 181.229 207.844 116.538 1.00 53.14  ? 5   VAL B C   1 
ATOM 33   O O   . VAL A 1 5   ? 181.223 206.758 117.127 1.00 53.14  ? 5   VAL B O   1 
ATOM 34   C CB  . VAL A 1 5   ? 183.497 208.823 117.001 1.00 53.14  ? 5   VAL B CB  1 
ATOM 35   C CG1 . VAL A 1 5   ? 183.880 208.598 115.547 1.00 53.14  ? 5   VAL B CG1 1 
ATOM 36   C CG2 . VAL A 1 5   ? 184.245 210.015 117.577 1.00 53.14  ? 5   VAL B CG2 1 
ATOM 37   N N   . GLN A 1 6   ? 180.611 208.045 115.380 1.00 54.59  ? 6   GLN B N   1 
ATOM 38   C CA  . GLN A 1 6   ? 179.871 206.996 114.701 1.00 54.59  ? 6   GLN B CA  1 
ATOM 39   C C   . GLN A 1 6   ? 180.686 206.438 113.538 1.00 54.59  ? 6   GLN B C   1 
ATOM 40   O O   . GLN A 1 6   ? 181.863 206.760 113.356 1.00 54.59  ? 6   GLN B O   1 
ATOM 41   C CB  . GLN A 1 6   ? 178.523 207.524 114.216 1.00 54.59  ? 6   GLN B CB  1 
ATOM 42   C CG  . GLN A 1 6   ? 177.553 207.898 115.313 1.00 54.59  ? 6   GLN B CG  1 
ATOM 43   C CD  . GLN A 1 6   ? 176.250 208.422 114.755 1.00 54.59  ? 6   GLN B CD  1 
ATOM 44   O OE1 . GLN A 1 6   ? 176.094 208.565 113.545 1.00 54.59  ? 6   GLN B OE1 1 
ATOM 45   N NE2 . GLN A 1 6   ? 175.304 208.706 115.633 1.00 54.59  ? 6   GLN B NE2 1 
ATOM 46   N N   . SER A 1 7   ? 180.051 205.589 112.737 1.00 60.43  ? 7   SER B N   1 
ATOM 47   C CA  . SER A 1 7   ? 180.670 205.038 111.541 1.00 60.43  ? 7   SER B CA  1 
ATOM 48   C C   . SER A 1 7   ? 180.546 206.046 110.399 1.00 60.43  ? 7   SER B C   1 
ATOM 49   O O   . SER A 1 7   ? 180.182 207.208 110.598 1.00 60.43  ? 7   SER B O   1 
ATOM 50   C CB  . SER A 1 7   ? 180.039 203.693 111.189 1.00 60.43  ? 7   SER B CB  1 
ATOM 51   O OG  . SER A 1 7   ? 178.711 203.860 110.728 1.00 60.43  ? 7   SER B OG  1 
ATOM 52   N N   . GLY A 1 8   ? 180.849 205.608 109.180 1.00 64.20  ? 8   GLY B N   1 
ATOM 53   C CA  . GLY A 1 8   ? 180.760 206.459 108.015 1.00 64.20  ? 8   GLY B CA  1 
ATOM 54   C C   . GLY A 1 8   ? 179.341 206.562 107.487 1.00 64.20  ? 8   GLY B C   1 
ATOM 55   O O   . GLY A 1 8   ? 178.371 206.131 108.111 1.00 64.20  ? 8   GLY B O   1 
ATOM 56   N N   . ALA A 1 9   ? 179.228 207.156 106.300 1.00 69.08  ? 9   ALA B N   1 
ATOM 57   C CA  . ALA A 1 9   ? 177.935 207.358 105.648 1.00 69.08  ? 9   ALA B CA  1 
ATOM 58   C C   . ALA A 1 9   ? 177.577 206.090 104.885 1.00 69.08  ? 9   ALA B C   1 
ATOM 59   O O   . ALA A 1 9   ? 177.884 205.942 103.701 1.00 69.08  ? 9   ALA B O   1 
ATOM 60   C CB  . ALA A 1 9   ? 177.976 208.573 104.731 1.00 69.08  ? 9   ALA B CB  1 
ATOM 61   N N   . GLU A 1 10  ? 176.919 205.161 105.576 1.00 68.88  ? 10  GLU B N   1 
ATOM 62   C CA  . GLU A 1 10  ? 176.531 203.899 104.959 1.00 68.88  ? 10  GLU B CA  1 
ATOM 63   C C   . GLU A 1 10  ? 175.576 204.139 103.797 1.00 68.88  ? 10  GLU B C   1 
ATOM 64   O O   . GLU A 1 10  ? 174.659 204.961 103.888 1.00 68.88  ? 10  GLU B O   1 
ATOM 65   C CB  . GLU A 1 10  ? 175.881 202.983 105.995 1.00 68.88  ? 10  GLU B CB  1 
ATOM 66   C CG  . GLU A 1 10  ? 176.854 202.080 106.732 1.00 68.88  ? 10  GLU B CG  1 
ATOM 67   C CD  . GLU A 1 10  ? 177.322 202.670 108.043 1.00 68.88  ? 10  GLU B CD  1 
ATOM 68   O OE1 . GLU A 1 10  ? 176.894 203.794 108.375 1.00 68.88  ? 10  GLU B OE1 1 
ATOM 69   O OE2 . GLU A 1 10  ? 178.115 202.009 108.745 1.00 68.88  ? 10  GLU B OE2 1 
ATOM 70   N N   . VAL A 1 11  ? 175.799 203.422 102.699 1.00 78.73  ? 11  VAL B N   1 
ATOM 71   C CA  . VAL A 1 11  ? 174.953 203.493 101.512 1.00 78.73  ? 11  VAL B CA  1 
ATOM 72   C C   . VAL A 1 11  ? 174.519 202.068 101.195 1.00 78.73  ? 11  VAL B C   1 
ATOM 73   O O   . VAL A 1 11  ? 175.289 201.286 100.625 1.00 78.73  ? 11  VAL B O   1 
ATOM 74   C CB  . VAL A 1 11  ? 175.672 204.134 100.321 1.00 78.73  ? 11  VAL B CB  1 
ATOM 75   C CG1 . VAL A 1 11  ? 174.712 204.311 99.154  1.00 78.73  ? 11  VAL B CG1 1 
ATOM 76   C CG2 . VAL A 1 11  ? 176.284 205.468 100.723 1.00 78.73  ? 11  VAL B CG2 1 
ATOM 77   N N   . LYS A 1 12  ? 173.286 201.723 101.560 1.00 80.11  ? 12  LYS B N   1 
ATOM 78   C CA  . LYS A 1 12  ? 172.743 200.393 101.325 1.00 80.11  ? 12  LYS B CA  1 
ATOM 79   C C   . LYS A 1 12  ? 171.431 200.485 100.560 1.00 80.11  ? 12  LYS B C   1 
ATOM 80   O O   . LYS A 1 12  ? 170.694 201.468 100.669 1.00 80.11  ? 12  LYS B O   1 
ATOM 81   C CB  . LYS A 1 12  ? 172.529 199.624 102.640 1.00 80.11  ? 12  LYS B CB  1 
ATOM 82   C CG  . LYS A 1 12  ? 173.746 198.840 103.117 1.00 80.11  ? 12  LYS B CG  1 
ATOM 83   C CD  . LYS A 1 12  ? 174.858 199.727 103.644 1.00 80.11  ? 12  LYS B CD  1 
ATOM 84   C CE  . LYS A 1 12  ? 176.011 198.881 104.163 1.00 80.11  ? 12  LYS B CE  1 
ATOM 85   N NZ  . LYS A 1 12  ? 177.191 199.698 104.550 1.00 80.11  ? 12  LYS B NZ  1 
ATOM 86   N N   . LYS A 1 13  ? 171.155 199.443 99.780  1.00 84.48  ? 13  LYS B N   1 
ATOM 87   C CA  . LYS A 1 13  ? 169.949 199.390 98.975  1.00 84.48  ? 13  LYS B CA  1 
ATOM 88   C C   . LYS A 1 13  ? 168.716 199.238 99.865  1.00 84.48  ? 13  LYS B C   1 
ATOM 89   O O   . LYS A 1 13  ? 168.809 198.746 100.992 1.00 84.48  ? 13  LYS B O   1 
ATOM 90   C CB  . LYS A 1 13  ? 170.029 198.231 97.983  1.00 84.48  ? 13  LYS B CB  1 
ATOM 91   N N   . PRO A 1 14  ? 167.550 199.674 99.384  1.00 84.87  ? 14  PRO B N   1 
ATOM 92   C CA  . PRO A 1 14  ? 166.322 199.502 100.172 1.00 84.87  ? 14  PRO B CA  1 
ATOM 93   C C   . PRO A 1 14  ? 166.034 198.033 100.441 1.00 84.87  ? 14  PRO B C   1 
ATOM 94   O O   . PRO A 1 14  ? 166.296 197.160 99.610  1.00 84.87  ? 14  PRO B O   1 
ATOM 95   C CB  . PRO A 1 14  ? 165.228 200.132 99.299  1.00 84.87  ? 14  PRO B CB  1 
ATOM 96   C CG  . PRO A 1 14  ? 165.897 200.770 98.150  1.00 84.87  ? 14  PRO B CG  1 
ATOM 97   C CD  . PRO A 1 14  ? 167.351 200.463 98.156  1.00 84.87  ? 14  PRO B CD  1 
ATOM 98   N N   . GLY A 1 15  ? 165.485 197.767 101.625 1.00 83.50  ? 15  GLY B N   1 
ATOM 99   C CA  . GLY A 1 15  ? 165.174 196.421 102.049 1.00 83.50  ? 15  GLY B CA  1 
ATOM 100  C C   . GLY A 1 15  ? 166.289 195.706 102.779 1.00 83.50  ? 15  GLY B C   1 
ATOM 101  O O   . GLY A 1 15  ? 166.057 194.615 103.315 1.00 83.50  ? 15  GLY B O   1 
ATOM 102  N N   . SER A 1 16  ? 167.486 196.281 102.821 1.00 84.05  ? 16  SER B N   1 
ATOM 103  C CA  . SER A 1 16  ? 168.616 195.681 103.512 1.00 84.05  ? 16  SER B CA  1 
ATOM 104  C C   . SER A 1 16  ? 168.656 196.183 104.954 1.00 84.05  ? 16  SER B C   1 
ATOM 105  O O   . SER A 1 16  ? 167.708 196.799 105.449 1.00 84.05  ? 16  SER B O   1 
ATOM 106  C CB  . SER A 1 16  ? 169.912 195.983 102.763 1.00 84.05  ? 16  SER B CB  1 
ATOM 107  O OG  . SER A 1 16  ? 170.169 197.376 102.736 1.00 84.05  ? 16  SER B OG  1 
ATOM 108  N N   . SER A 1 17  ? 169.760 195.920 105.648 1.00 79.51  ? 17  SER B N   1 
ATOM 109  C CA  . SER A 1 17  ? 169.926 196.347 107.028 1.00 79.51  ? 17  SER B CA  1 
ATOM 110  C C   . SER A 1 17  ? 171.310 196.951 107.205 1.00 79.51  ? 17  SER B C   1 
ATOM 111  O O   . SER A 1 17  ? 172.244 196.633 106.464 1.00 79.51  ? 17  SER B O   1 
ATOM 112  C CB  . SER A 1 17  ? 169.730 195.183 108.007 1.00 79.51  ? 17  SER B CB  1 
ATOM 113  O OG  . SER A 1 17  ? 169.925 195.604 109.345 1.00 79.51  ? 17  SER B OG  1 
ATOM 114  N N   . VAL A 1 18  ? 171.433 197.830 108.200 1.00 71.98  ? 18  VAL B N   1 
ATOM 115  C CA  . VAL A 1 18  ? 172.691 198.490 108.515 1.00 71.98  ? 18  VAL B CA  1 
ATOM 116  C C   . VAL A 1 18  ? 172.995 198.281 109.992 1.00 71.98  ? 18  VAL B C   1 
ATOM 117  O O   . VAL A 1 18  ? 172.115 197.975 110.798 1.00 71.98  ? 18  VAL B O   1 
ATOM 118  C CB  . VAL A 1 18  ? 172.668 199.996 108.179 1.00 71.98  ? 18  VAL B CB  1 
ATOM 119  C CG1 . VAL A 1 18  ? 172.449 200.206 106.688 1.00 71.98  ? 18  VAL B CG1 1 
ATOM 120  C CG2 . VAL A 1 18  ? 171.597 200.703 108.987 1.00 71.98  ? 18  VAL B CG2 1 
ATOM 121  N N   . LYS A 1 19  ? 174.268 198.452 110.337 1.00 63.74  ? 19  LYS B N   1 
ATOM 122  C CA  . LYS A 1 19  ? 174.774 198.218 111.685 1.00 63.74  ? 19  LYS B CA  1 
ATOM 123  C C   . LYS A 1 19  ? 175.591 199.412 112.157 1.00 63.74  ? 19  LYS B C   1 
ATOM 124  O O   . LYS A 1 19  ? 176.726 199.279 112.619 1.00 63.74  ? 19  LYS B O   1 
ATOM 125  C CB  . LYS A 1 19  ? 175.602 196.938 111.742 1.00 63.74  ? 19  LYS B CB  1 
ATOM 126  N N   . VAL A 1 20  ? 175.015 200.610 112.023 1.00 56.59  ? 20  VAL B N   1 
ATOM 127  C CA  . VAL A 1 20  ? 175.708 201.823 112.435 1.00 56.59  ? 20  VAL B CA  1 
ATOM 128  C C   . VAL A 1 20  ? 176.067 201.751 113.918 1.00 56.59  ? 20  VAL B C   1 
ATOM 129  O O   . VAL A 1 20  ? 175.336 201.179 114.736 1.00 56.59  ? 20  VAL B O   1 
ATOM 130  C CB  . VAL A 1 20  ? 174.853 203.065 112.133 1.00 56.59  ? 20  VAL B CB  1 
ATOM 131  C CG1 . VAL A 1 20  ? 174.608 203.183 110.642 1.00 56.59  ? 20  VAL B CG1 1 
ATOM 132  C CG2 . VAL A 1 20  ? 173.531 202.981 112.865 1.00 56.59  ? 20  VAL B CG2 1 
ATOM 133  N N   . SER A 1 21  ? 177.215 202.325 114.260 1.00 54.25  ? 21  SER B N   1 
ATOM 134  C CA  . SER A 1 21  ? 177.772 202.249 115.601 1.00 54.25  ? 21  SER B CA  1 
ATOM 135  C C   . SER A 1 21  ? 177.860 203.641 116.212 1.00 54.25  ? 21  SER B C   1 
ATOM 136  O O   . SER A 1 21  ? 177.610 204.653 115.555 1.00 54.25  ? 21  SER B O   1 
ATOM 137  C CB  . SER A 1 21  ? 179.157 201.592 115.580 1.00 54.25  ? 21  SER B CB  1 
ATOM 138  O OG  . SER A 1 21  ? 180.069 202.353 114.808 1.00 54.25  ? 21  SER B OG  1 
ATOM 139  N N   . CYS A 1 22  ? 178.224 203.679 117.496 1.00 52.81  ? 22  CYS B N   1 
ATOM 140  C CA  . CYS A 1 22  ? 178.375 204.947 118.206 1.00 52.81  ? 22  CYS B CA  1 
ATOM 141  C C   . CYS A 1 22  ? 179.337 204.708 119.369 1.00 52.81  ? 22  CYS B C   1 
ATOM 142  O O   . CYS A 1 22  ? 178.939 204.153 120.397 1.00 52.81  ? 22  CYS B O   1 
ATOM 143  C CB  . CYS A 1 22  ? 177.031 205.470 118.689 1.00 52.81  ? 22  CYS B CB  1 
ATOM 144  S SG  . CYS A 1 22  ? 177.118 206.894 119.796 1.00 52.81  ? 22  CYS B SG  1 
ATOM 145  N N   . LYS A 1 23  ? 180.586 205.129 119.198 1.00 53.95  ? 23  LYS B N   1 
ATOM 146  C CA  . LYS A 1 23  ? 181.599 204.948 120.230 1.00 53.95  ? 23  LYS B CA  1 
ATOM 147  C C   . LYS A 1 23  ? 181.497 206.074 121.250 1.00 53.95  ? 23  LYS B C   1 
ATOM 148  O O   . LYS A 1 23  ? 181.625 207.251 120.899 1.00 53.95  ? 23  LYS B O   1 
ATOM 149  C CB  . LYS A 1 23  ? 182.993 204.907 119.607 1.00 53.95  ? 23  LYS B CB  1 
ATOM 150  N N   . ALA A 1 24  ? 181.270 205.713 122.513 1.00 53.44  ? 24  ALA B N   1 
ATOM 151  C CA  . ALA A 1 24  ? 181.134 206.693 123.590 1.00 53.44  ? 24  ALA B CA  1 
ATOM 152  C C   . ALA A 1 24  ? 182.509 206.938 124.206 1.00 53.44  ? 24  ALA B C   1 
ATOM 153  O O   . ALA A 1 24  ? 182.831 206.478 125.303 1.00 53.44  ? 24  ALA B O   1 
ATOM 154  C CB  . ALA A 1 24  ? 180.126 206.215 124.626 1.00 53.44  ? 24  ALA B CB  1 
ATOM 155  N N   . SER A 1 25  ? 183.331 207.688 123.476 1.00 57.40  ? 25  SER B N   1 
ATOM 156  C CA  . SER A 1 25  ? 184.686 207.997 123.923 1.00 57.40  ? 25  SER B CA  1 
ATOM 157  C C   . SER A 1 25  ? 184.626 208.927 125.128 1.00 57.40  ? 25  SER B C   1 
ATOM 158  O O   . SER A 1 25  ? 184.337 210.119 124.989 1.00 57.40  ? 25  SER B O   1 
ATOM 159  C CB  . SER A 1 25  ? 185.485 208.629 122.787 1.00 57.40  ? 25  SER B CB  1 
ATOM 160  O OG  . SER A 1 25  ? 186.794 208.967 123.213 1.00 57.40  ? 25  SER B OG  1 
ATOM 161  N N   . GLY A 1 26  ? 184.907 208.391 126.301 1.00 61.22  ? 26  GLY B N   1 
ATOM 162  C CA  . GLY A 1 26  ? 184.855 209.154 127.529 1.00 61.22  ? 26  GLY B CA  1 
ATOM 163  C C   . GLY A 1 26  ? 183.628 208.804 128.353 1.00 61.22  ? 26  GLY B C   1 
ATOM 164  O O   . GLY A 1 26  ? 182.595 208.363 127.831 1.00 61.22  ? 26  GLY B O   1 
ATOM 165  N N   . GLY A 1 27  ? 183.744 208.994 129.665 1.00 66.51  ? 27  GLY B N   1 
ATOM 166  C CA  . GLY A 1 27  ? 182.649 208.702 130.567 1.00 66.51  ? 27  GLY B CA  1 
ATOM 167  C C   . GLY A 1 27  ? 182.516 207.226 130.880 1.00 66.51  ? 27  GLY B C   1 
ATOM 168  O O   . GLY A 1 27  ? 182.712 206.380 130.002 1.00 66.51  ? 27  GLY B O   1 
ATOM 169  N N   . THR A 1 28  ? 182.183 206.903 132.126 1.00 69.97  ? 28  THR B N   1 
ATOM 170  C CA  . THR A 1 28  ? 182.023 205.513 132.518 1.00 69.97  ? 28  THR B CA  1 
ATOM 171  C C   . THR A 1 28  ? 180.766 204.919 131.885 1.00 69.97  ? 28  THR B C   1 
ATOM 172  O O   . THR A 1 28  ? 179.824 205.627 131.519 1.00 69.97  ? 28  THR B O   1 
ATOM 173  C CB  . THR A 1 28  ? 181.958 205.385 134.040 1.00 69.97  ? 28  THR B CB  1 
ATOM 174  O OG1 . THR A 1 28  ? 181.767 204.011 134.400 1.00 69.97  ? 28  THR B OG1 1 
ATOM 175  C CG2 . THR A 1 28  ? 180.814 206.215 134.598 1.00 69.97  ? 28  THR B CG2 1 
ATOM 176  N N   . PHE A 1 29  ? 180.765 203.590 131.757 1.00 68.81  ? 29  PHE B N   1 
ATOM 177  C CA  . PHE A 1 29  ? 179.660 202.887 131.115 1.00 68.81  ? 29  PHE B CA  1 
ATOM 178  C C   . PHE A 1 29  ? 178.389 202.877 131.953 1.00 68.81  ? 29  PHE B C   1 
ATOM 179  O O   . PHE A 1 29  ? 177.338 202.479 131.442 1.00 68.81  ? 29  PHE B O   1 
ATOM 180  C CB  . PHE A 1 29  ? 180.071 201.450 130.791 1.00 68.81  ? 29  PHE B CB  1 
ATOM 181  N N   . SER A 1 30  ? 178.455 203.296 133.217 1.00 68.13  ? 30  SER B N   1 
ATOM 182  C CA  . SER A 1 30  ? 177.302 203.289 134.106 1.00 68.13  ? 30  SER B CA  1 
ATOM 183  C C   . SER A 1 30  ? 176.721 204.680 134.325 1.00 68.13  ? 30  SER B C   1 
ATOM 184  O O   . SER A 1 30  ? 176.088 204.924 135.358 1.00 68.13  ? 30  SER B O   1 
ATOM 185  C CB  . SER A 1 30  ? 177.676 202.659 135.448 1.00 68.13  ? 30  SER B CB  1 
ATOM 186  O OG  . SER A 1 30  ? 176.579 202.682 136.344 1.00 68.13  ? 30  SER B OG  1 
ATOM 187  N N   . SER A 1 31  ? 176.923 205.599 133.380 1.00 63.92  ? 31  SER B N   1 
ATOM 188  C CA  . SER A 1 31  ? 176.406 206.950 133.531 1.00 63.92  ? 31  SER B CA  1 
ATOM 189  C C   . SER A 1 31  ? 175.786 207.527 132.266 1.00 63.92  ? 31  SER B C   1 
ATOM 190  O O   . SER A 1 31  ? 175.433 208.711 132.267 1.00 63.92  ? 31  SER B O   1 
ATOM 191  C CB  . SER A 1 31  ? 177.515 207.894 134.021 1.00 63.92  ? 31  SER B CB  1 
ATOM 192  O OG  . SER A 1 31  ? 177.950 207.533 135.320 1.00 63.92  ? 31  SER B OG  1 
ATOM 193  N N   . TYR A 1 32  ? 175.638 206.751 131.196 1.00 53.13  ? 32  TYR B N   1 
ATOM 194  C CA  . TYR A 1 32  ? 174.998 207.251 129.990 1.00 53.13  ? 32  TYR B CA  1 
ATOM 195  C C   . TYR A 1 32  ? 174.016 206.218 129.463 1.00 53.13  ? 32  TYR B C   1 
ATOM 196  O O   . TYR A 1 32  ? 174.190 205.013 129.659 1.00 53.13  ? 32  TYR B O   1 
ATOM 197  C CB  . TYR A 1 32  ? 176.020 207.609 128.901 1.00 53.13  ? 32  TYR B CB  1 
ATOM 198  C CG  . TYR A 1 32  ? 176.831 206.448 128.372 1.00 53.13  ? 32  TYR B CG  1 
ATOM 199  C CD1 . TYR A 1 32  ? 178.034 206.088 128.962 1.00 53.13  ? 32  TYR B CD1 1 
ATOM 200  C CD2 . TYR A 1 32  ? 176.407 205.728 127.263 1.00 53.13  ? 32  TYR B CD2 1 
ATOM 201  C CE1 . TYR A 1 32  ? 178.781 205.033 128.473 1.00 53.13  ? 32  TYR B CE1 1 
ATOM 202  C CE2 . TYR A 1 32  ? 177.146 204.672 126.768 1.00 53.13  ? 32  TYR B CE2 1 
ATOM 203  C CZ  . TYR A 1 32  ? 178.331 204.329 127.376 1.00 53.13  ? 32  TYR B CZ  1 
ATOM 204  O OH  . TYR A 1 32  ? 179.068 203.278 126.883 1.00 53.13  ? 32  TYR B OH  1 
ATOM 205  N N   . THR A 1 33  ? 172.976 206.710 128.796 1.00 39.97  ? 33  THR B N   1 
ATOM 206  C CA  . THR A 1 33  ? 171.978 205.881 128.126 1.00 39.97  ? 33  THR B CA  1 
ATOM 207  C C   . THR A 1 33  ? 171.958 206.315 126.666 1.00 39.97  ? 33  THR B C   1 
ATOM 208  O O   . THR A 1 33  ? 171.376 207.350 126.331 1.00 39.97  ? 33  THR B O   1 
ATOM 209  C CB  . THR A 1 33  ? 170.599 206.035 128.758 1.00 39.97  ? 33  THR B CB  1 
ATOM 210  O OG1 . THR A 1 33  ? 169.972 207.218 128.249 1.00 39.97  ? 33  THR B OG1 1 
ATOM 211  C CG2 . THR A 1 33  ? 170.711 206.151 130.263 1.00 39.97  ? 33  THR B CG2 1 
ATOM 212  N N   . ILE A 1 34  ? 172.596 205.529 125.800 1.00 36.93  ? 34  ILE B N   1 
ATOM 213  C CA  . ILE A 1 34  ? 172.694 205.898 124.394 1.00 36.93  ? 34  ILE B CA  1 
ATOM 214  C C   . ILE A 1 34  ? 171.300 205.929 123.790 1.00 36.93  ? 34  ILE B C   1 
ATOM 215  O O   . ILE A 1 34  ? 170.558 204.941 123.851 1.00 36.93  ? 34  ILE B O   1 
ATOM 216  C CB  . ILE A 1 34  ? 173.604 204.925 123.644 1.00 36.93  ? 34  ILE B CB  1 
ATOM 217  C CG1 . ILE A 1 34  ? 175.071 205.222 123.951 1.00 36.93  ? 34  ILE B CG1 1 
ATOM 218  C CG2 . ILE A 1 34  ? 173.336 204.998 122.149 1.00 36.93  ? 34  ILE B CG2 1 
ATOM 219  C CD1 . ILE A 1 34  ? 175.636 206.385 123.175 1.00 36.93  ? 34  ILE B CD1 1 
ATOM 220  N N   . SER A 1 35  ? 170.936 207.064 123.204 1.00 35.64  ? 35  SER B N   1 
ATOM 221  C CA  . SER A 1 35  ? 169.658 207.239 122.532 1.00 35.64  ? 35  SER B CA  1 
ATOM 222  C C   . SER A 1 35  ? 169.933 207.647 121.097 1.00 35.64  ? 35  SER B C   1 
ATOM 223  O O   . SER A 1 35  ? 170.703 208.581 120.854 1.00 35.64  ? 35  SER B O   1 
ATOM 224  C CB  . SER A 1 35  ? 168.810 208.308 123.218 1.00 35.64  ? 35  SER B CB  1 
ATOM 225  O OG  . SER A 1 35  ? 168.462 207.938 124.536 1.00 35.64  ? 35  SER B OG  1 
ATOM 226  N N   . TRP A 1 36  ? 169.306 206.962 120.152 1.00 40.54  ? 36  TRP B N   1 
ATOM 227  C CA  . TRP A 1 36  ? 169.513 207.246 118.741 1.00 40.54  ? 36  TRP B CA  1 
ATOM 228  C C   . TRP A 1 36  ? 168.381 208.124 118.234 1.00 40.54  ? 36  TRP B C   1 
ATOM 229  O O   . TRP A 1 36  ? 167.207 207.826 118.465 1.00 40.54  ? 36  TRP B O   1 
ATOM 230  C CB  . TRP A 1 36  ? 169.602 205.956 117.930 1.00 40.54  ? 36  TRP B CB  1 
ATOM 231  C CG  . TRP A 1 36  ? 170.921 205.274 118.085 1.00 40.54  ? 36  TRP B CG  1 
ATOM 232  C CD1 . TRP A 1 36  ? 171.352 204.567 119.166 1.00 40.54  ? 36  TRP B CD1 1 
ATOM 233  C CD2 . TRP A 1 36  ? 171.996 205.255 117.140 1.00 40.54  ? 36  TRP B CD2 1 
ATOM 234  N NE1 . TRP A 1 36  ? 172.622 204.096 118.949 1.00 40.54  ? 36  TRP B NE1 1 
ATOM 235  C CE2 . TRP A 1 36  ? 173.040 204.507 117.711 1.00 40.54  ? 36  TRP B CE2 1 
ATOM 236  C CE3 . TRP A 1 36  ? 172.174 205.796 115.863 1.00 40.54  ? 36  TRP B CE3 1 
ATOM 237  C CZ2 . TRP A 1 36  ? 174.244 204.283 117.050 1.00 40.54  ? 36  TRP B CZ2 1 
ATOM 238  C CZ3 . TRP A 1 36  ? 173.370 205.573 115.210 1.00 40.54  ? 36  TRP B CZ3 1 
ATOM 239  C CH2 . TRP A 1 36  ? 174.389 204.823 115.803 1.00 40.54  ? 36  TRP B CH2 1 
ATOM 240  N N   . VAL A 1 37  ? 168.742 209.211 117.558 1.00 40.79  ? 37  VAL B N   1 
ATOM 241  C CA  . VAL A 1 37  ? 167.790 210.176 117.027 1.00 40.79  ? 37  VAL B CA  1 
ATOM 242  C C   . VAL A 1 37  ? 168.105 210.385 115.553 1.00 40.79  ? 37  VAL B C   1 
ATOM 243  O O   . VAL A 1 37  ? 169.261 210.630 115.192 1.00 40.79  ? 37  VAL B O   1 
ATOM 244  C CB  . VAL A 1 37  ? 167.853 211.507 117.797 1.00 40.79  ? 37  VAL B CB  1 
ATOM 245  C CG1 . VAL A 1 37  ? 166.813 212.462 117.277 1.00 40.79  ? 37  VAL B CG1 1 
ATOM 246  C CG2 . VAL A 1 37  ? 167.669 211.273 119.284 1.00 40.79  ? 37  VAL B CG2 1 
ATOM 247  N N   . ARG A 1 38  ? 167.087 210.288 114.705 1.00 50.11  ? 38  ARG B N   1 
ATOM 248  C CA  . ARG A 1 38  ? 167.253 210.403 113.263 1.00 50.11  ? 38  ARG B CA  1 
ATOM 249  C C   . ARG A 1 38  ? 166.722 211.742 112.773 1.00 50.11  ? 38  ARG B C   1 
ATOM 250  O O   . ARG A 1 38  ? 165.796 212.307 113.362 1.00 50.11  ? 38  ARG B O   1 
ATOM 251  C CB  . ARG A 1 38  ? 166.539 209.264 112.530 1.00 50.11  ? 38  ARG B CB  1 
ATOM 252  C CG  . ARG A 1 38  ? 165.061 209.173 112.834 1.00 50.11  ? 38  ARG B CG  1 
ATOM 253  C CD  . ARG A 1 38  ? 164.379 208.079 112.036 1.00 50.11  ? 38  ARG B CD  1 
ATOM 254  N NE  . ARG A 1 38  ? 164.243 208.440 110.631 1.00 50.11  ? 38  ARG B NE  1 
ATOM 255  C CZ  . ARG A 1 38  ? 163.856 207.605 109.678 1.00 50.11  ? 38  ARG B CZ  1 
ATOM 256  N NH1 . ARG A 1 38  ? 163.561 206.343 109.941 1.00 50.11  ? 38  ARG B NH1 1 
ATOM 257  N NH2 . ARG A 1 38  ? 163.757 208.050 108.429 1.00 50.11  ? 38  ARG B NH2 1 
ATOM 258  N N   . GLN A 1 39  ? 167.316 212.247 111.694 1.00 50.84  ? 39  GLN B N   1 
ATOM 259  C CA  . GLN A 1 39  ? 166.925 213.520 111.097 1.00 50.84  ? 39  GLN B CA  1 
ATOM 260  C C   . GLN A 1 39  ? 166.869 213.365 109.585 1.00 50.84  ? 39  GLN B C   1 
ATOM 261  O O   . GLN A 1 39  ? 167.910 213.274 108.928 1.00 50.84  ? 39  GLN B O   1 
ATOM 262  C CB  . GLN A 1 39  ? 167.896 214.634 111.482 1.00 50.84  ? 39  GLN B CB  1 
ATOM 263  C CG  . GLN A 1 39  ? 167.544 215.985 110.888 1.00 50.84  ? 39  GLN B CG  1 
ATOM 264  C CD  . GLN A 1 39  ? 168.323 217.119 111.517 1.00 50.84  ? 39  GLN B CD  1 
ATOM 265  O OE1 . GLN A 1 39  ? 169.228 216.896 112.319 1.00 50.84  ? 39  GLN B OE1 1 
ATOM 266  N NE2 . GLN A 1 39  ? 167.974 218.348 111.155 1.00 50.84  ? 39  GLN B NE2 1 
ATOM 267  N N   . ALA A 1 40  ? 165.660 213.334 109.036 1.00 57.17  ? 40  ALA B N   1 
ATOM 268  C CA  . ALA A 1 40  ? 165.502 213.371 107.594 1.00 57.17  ? 40  ALA B CA  1 
ATOM 269  C C   . ALA A 1 40  ? 165.923 214.743 107.063 1.00 57.17  ? 40  ALA B C   1 
ATOM 270  O O   . ALA A 1 40  ? 165.826 215.745 107.776 1.00 57.17  ? 40  ALA B O   1 
ATOM 271  C CB  . ALA A 1 40  ? 164.054 213.076 107.211 1.00 57.17  ? 40  ALA B CB  1 
ATOM 272  N N   . PRO A 1 41  ? 166.399 214.818 105.819 1.00 62.06  ? 41  PRO B N   1 
ATOM 273  C CA  . PRO A 1 41  ? 166.830 216.119 105.284 1.00 62.06  ? 41  PRO B CA  1 
ATOM 274  C C   . PRO A 1 41  ? 165.634 217.021 105.023 1.00 62.06  ? 41  PRO B C   1 
ATOM 275  O O   . PRO A 1 41  ? 164.716 216.669 104.278 1.00 62.06  ? 41  PRO B O   1 
ATOM 276  C CB  . PRO A 1 41  ? 167.568 215.749 103.992 1.00 62.06  ? 41  PRO B CB  1 
ATOM 277  C CG  . PRO A 1 41  ? 167.071 214.401 103.610 1.00 62.06  ? 41  PRO B CG  1 
ATOM 278  C CD  . PRO A 1 41  ? 166.397 213.762 104.791 1.00 62.06  ? 41  PRO B CD  1 
ATOM 279  N N   . GLY A 1 42  ? 165.653 218.197 105.646 1.00 60.59  ? 42  GLY B N   1 
ATOM 280  C CA  . GLY A 1 42  ? 164.526 219.102 105.583 1.00 60.59  ? 42  GLY B CA  1 
ATOM 281  C C   . GLY A 1 42  ? 163.416 218.801 106.562 1.00 60.59  ? 42  GLY B C   1 
ATOM 282  O O   . GLY A 1 42  ? 162.353 219.427 106.480 1.00 60.59  ? 42  GLY B O   1 
ATOM 283  N N   . GLN A 1 43  ? 163.625 217.865 107.484 1.00 56.71  ? 43  GLN B N   1 
ATOM 284  C CA  . GLN A 1 43  ? 162.618 217.479 108.459 1.00 56.71  ? 43  GLN B CA  1 
ATOM 285  C C   . GLN A 1 43  ? 163.249 217.463 109.845 1.00 56.71  ? 43  GLN B C   1 
ATOM 286  O O   . GLN A 1 43  ? 164.452 217.240 109.999 1.00 56.71  ? 43  GLN B O   1 
ATOM 287  C CB  . GLN A 1 43  ? 162.015 216.104 108.118 1.00 56.71  ? 43  GLN B CB  1 
ATOM 288  C CG  . GLN A 1 43  ? 160.889 215.622 109.032 1.00 56.71  ? 43  GLN B CG  1 
ATOM 289  C CD  . GLN A 1 43  ? 159.642 216.494 108.983 1.00 56.71  ? 43  GLN B CD  1 
ATOM 290  O OE1 . GLN A 1 43  ? 159.584 217.490 108.262 1.00 56.71  ? 43  GLN B OE1 1 
ATOM 291  N NE2 . GLN A 1 43  ? 158.634 216.114 109.757 1.00 56.71  ? 43  GLN B NE2 1 
ATOM 292  N N   . GLY A 1 44  ? 162.421 217.704 110.856 1.00 53.56  ? 44  GLY B N   1 
ATOM 293  C CA  . GLY A 1 44  ? 162.892 217.754 112.222 1.00 53.56  ? 44  GLY B CA  1 
ATOM 294  C C   . GLY A 1 44  ? 163.351 216.397 112.724 1.00 53.56  ? 44  GLY B C   1 
ATOM 295  O O   . GLY A 1 44  ? 163.200 215.361 112.076 1.00 53.56  ? 44  GLY B O   1 
ATOM 296  N N   . LEU A 1 45  ? 163.937 216.417 113.916 1.00 44.79  ? 45  LEU B N   1 
ATOM 297  C CA  . LEU A 1 45  ? 164.497 215.209 114.501 1.00 44.79  ? 45  LEU B CA  1 
ATOM 298  C C   . LEU A 1 45  ? 163.400 214.214 114.865 1.00 44.79  ? 45  LEU B C   1 
ATOM 299  O O   . LEU A 1 45  ? 162.262 214.585 115.165 1.00 44.79  ? 45  LEU B O   1 
ATOM 300  C CB  . LEU A 1 45  ? 165.333 215.550 115.735 1.00 44.79  ? 45  LEU B CB  1 
ATOM 301  C CG  . LEU A 1 45  ? 166.786 216.000 115.533 1.00 44.79  ? 45  LEU B CG  1 
ATOM 302  C CD1 . LEU A 1 45  ? 167.622 214.897 114.924 1.00 44.79  ? 45  LEU B CD1 1 
ATOM 303  C CD2 . LEU A 1 45  ? 166.875 217.232 114.664 1.00 44.79  ? 45  LEU B CD2 1 
ATOM 304  N N   . GLU A 1 46  ? 163.759 212.933 114.828 1.00 46.02  ? 46  GLU B N   1 
ATOM 305  C CA  . GLU A 1 46  ? 162.852 211.841 115.151 1.00 46.02  ? 46  GLU B CA  1 
ATOM 306  C C   . GLU A 1 46  ? 163.616 210.810 115.966 1.00 46.02  ? 46  GLU B C   1 
ATOM 307  O O   . GLU A 1 46  ? 164.774 210.515 115.661 1.00 46.02  ? 46  GLU B O   1 
ATOM 308  C CB  . GLU A 1 46  ? 162.276 211.213 113.877 1.00 46.02  ? 46  GLU B CB  1 
ATOM 309  C CG  . GLU A 1 46  ? 161.528 209.912 114.091 1.00 46.02  ? 46  GLU B CG  1 
ATOM 310  C CD  . GLU A 1 46  ? 160.697 209.517 112.885 1.00 46.02  ? 46  GLU B CD  1 
ATOM 311  O OE1 . GLU A 1 46  ? 161.051 209.921 111.758 1.00 46.02  ? 46  GLU B OE1 1 
ATOM 312  O OE2 . GLU A 1 46  ? 159.688 208.805 113.065 1.00 46.02  ? 46  GLU B OE2 1 
ATOM 313  N N   . TRP A 1 47  ? 162.973 210.269 116.995 1.00 42.51  ? 47  TRP B N   1 
ATOM 314  C CA  . TRP A 1 47  ? 163.623 209.397 117.962 1.00 42.51  ? 47  TRP B CA  1 
ATOM 315  C C   . TRP A 1 47  ? 163.149 207.960 117.783 1.00 42.51  ? 47  TRP B C   1 
ATOM 316  O O   . TRP A 1 47  ? 161.944 207.699 117.725 1.00 42.51  ? 47  TRP B O   1 
ATOM 317  C CB  . TRP A 1 47  ? 163.323 209.887 119.379 1.00 42.51  ? 47  TRP B CB  1 
ATOM 318  C CG  . TRP A 1 47  ? 163.854 209.033 120.475 1.00 42.51  ? 47  TRP B CG  1 
ATOM 319  C CD1 . TRP A 1 47  ? 165.044 209.180 121.118 1.00 42.51  ? 47  TRP B CD1 1 
ATOM 320  C CD2 . TRP A 1 47  ? 163.204 207.912 121.081 1.00 42.51  ? 47  TRP B CD2 1 
ATOM 321  N NE1 . TRP A 1 47  ? 165.182 208.215 122.082 1.00 42.51  ? 47  TRP B NE1 1 
ATOM 322  C CE2 . TRP A 1 47  ? 164.065 207.422 122.079 1.00 42.51  ? 47  TRP B CE2 1 
ATOM 323  C CE3 . TRP A 1 47  ? 161.979 207.272 120.875 1.00 42.51  ? 47  TRP B CE3 1 
ATOM 324  C CZ2 . TRP A 1 47  ? 163.741 206.325 122.870 1.00 42.51  ? 47  TRP B CZ2 1 
ATOM 325  C CZ3 . TRP A 1 47  ? 161.661 206.181 121.660 1.00 42.51  ? 47  TRP B CZ3 1 
ATOM 326  C CH2 . TRP A 1 47  ? 162.538 205.719 122.643 1.00 42.51  ? 47  TRP B CH2 1 
ATOM 327  N N   . MET A 1 48  ? 164.101 207.025 117.693 1.00 50.80  ? 48  MET B N   1 
ATOM 328  C CA  . MET A 1 48  ? 163.780 205.614 117.498 1.00 50.80  ? 48  MET B CA  1 
ATOM 329  C C   . MET A 1 48  ? 163.834 204.806 118.789 1.00 50.80  ? 48  MET B C   1 
ATOM 330  O O   . MET A 1 48  ? 162.843 204.163 119.147 1.00 50.80  ? 48  MET B O   1 
ATOM 331  C CB  . MET A 1 48  ? 164.692 204.972 116.439 1.00 50.80  ? 48  MET B CB  1 
ATOM 332  C CG  . MET A 1 48  ? 164.629 205.618 115.066 1.00 50.80  ? 48  MET B CG  1 
ATOM 333  S SD  . MET A 1 48  ? 166.224 205.882 114.277 1.00 50.80  ? 48  MET B SD  1 
ATOM 334  C CE  . MET A 1 48  ? 166.992 207.006 115.422 1.00 50.80  ? 48  MET B CE  1 
ATOM 335  N N   . GLY A 1 49  ? 164.959 204.800 119.500 1.00 43.68  ? 49  GLY B N   1 
ATOM 336  C CA  . GLY A 1 49  ? 165.030 203.992 120.703 1.00 43.68  ? 49  GLY B CA  1 
ATOM 337  C C   . GLY A 1 49  ? 166.332 204.055 121.473 1.00 43.68  ? 49  GLY B C   1 
ATOM 338  O O   . GLY A 1 49  ? 167.414 204.006 120.883 1.00 43.68  ? 49  GLY B O   1 
ATOM 339  N N   . ARG A 1 50  ? 166.239 204.145 122.794 1.00 44.23  ? 50  ARG B N   1 
ATOM 340  C CA  . ARG A 1 50  ? 167.416 204.219 123.644 1.00 44.23  ? 50  ARG B CA  1 
ATOM 341  C C   . ARG A 1 50  ? 167.788 202.848 124.191 1.00 44.23  ? 50  ARG B C   1 
ATOM 342  O O   . ARG A 1 50  ? 167.005 201.898 124.151 1.00 44.23  ? 50  ARG B O   1 
ATOM 343  C CB  . ARG A 1 50  ? 167.193 205.195 124.800 1.00 44.23  ? 50  ARG B CB  1 
ATOM 344  C CG  . ARG A 1 50  ? 165.972 204.925 125.658 1.00 44.23  ? 50  ARG B CG  1 
ATOM 345  C CD  . ARG A 1 50  ? 166.267 203.982 126.813 1.00 44.23  ? 50  ARG B CD  1 
ATOM 346  N NE  . ARG A 1 50  ? 165.129 203.855 127.714 1.00 44.23  ? 50  ARG B NE  1 
ATOM 347  C CZ  . ARG A 1 50  ? 165.015 202.922 128.648 1.00 44.23  ? 50  ARG B CZ  1 
ATOM 348  N NH1 . ARG A 1 50  ? 165.945 201.999 128.818 1.00 44.23  ? 50  ARG B NH1 1 
ATOM 349  N NH2 . ARG A 1 50  ? 163.935 202.909 129.424 1.00 44.23  ? 50  ARG B NH2 1 
ATOM 350  N N   . ILE A 1 51  ? 169.009 202.761 124.714 1.00 46.87  ? 51  ILE B N   1 
ATOM 351  C CA  . ILE A 1 51  ? 169.498 201.569 125.392 1.00 46.87  ? 51  ILE B CA  1 
ATOM 352  C C   . ILE A 1 51  ? 170.262 202.009 126.632 1.00 46.87  ? 51  ILE B C   1 
ATOM 353  O O   . ILE A 1 51  ? 170.864 203.086 126.664 1.00 46.87  ? 51  ILE B O   1 
ATOM 354  C CB  . ILE A 1 51  ? 170.388 200.701 124.471 1.00 46.87  ? 51  ILE B CB  1 
ATOM 355  C CG1 . ILE A 1 51  ? 170.660 199.336 125.106 1.00 46.87  ? 51  ILE B CG1 1 
ATOM 356  C CG2 . ILE A 1 51  ? 171.698 201.401 124.167 1.00 46.87  ? 51  ILE B CG2 1 
ATOM 357  C CD1 . ILE A 1 51  ? 171.032 198.266 124.107 1.00 46.87  ? 51  ILE B CD1 1 
ATOM 358  N N   . ILE A 1 52  ? 170.219 201.177 127.666 1.00 51.24  ? 52  ILE B N   1 
ATOM 359  C CA  . ILE A 1 52  ? 171.009 201.420 128.868 1.00 51.24  ? 52  ILE B CA  1 
ATOM 360  C C   . ILE A 1 52  ? 172.070 200.330 128.954 1.00 51.24  ? 52  ILE B C   1 
ATOM 361  O O   . ILE A 1 52  ? 171.762 199.196 129.349 1.00 51.24  ? 52  ILE B O   1 
ATOM 362  C CB  . ILE A 1 52  ? 170.129 201.452 130.125 1.00 51.24  ? 52  ILE B CB  1 
ATOM 363  C CG1 . ILE A 1 52  ? 169.090 202.563 130.015 1.00 51.24  ? 52  ILE B CG1 1 
ATOM 364  C CG2 . ILE A 1 52  ? 170.973 201.679 131.356 1.00 51.24  ? 52  ILE B CG2 1 
ATOM 365  C CD1 . ILE A 1 52  ? 168.119 202.579 131.163 1.00 51.24  ? 52  ILE B CD1 1 
ATOM 366  N N   . PRO A 1 53  ? 173.321 200.621 128.588 1.00 54.23  ? 53  PRO B N   1 
ATOM 367  C CA  . PRO A 1 53  ? 174.336 199.554 128.546 1.00 54.23  ? 53  PRO B CA  1 
ATOM 368  C C   . PRO A 1 53  ? 174.562 198.863 129.879 1.00 54.23  ? 53  PRO B C   1 
ATOM 369  O O   . PRO A 1 53  ? 174.796 197.649 129.906 1.00 54.23  ? 53  PRO B O   1 
ATOM 370  C CB  . PRO A 1 53  ? 175.595 200.294 128.068 1.00 54.23  ? 53  PRO B CB  1 
ATOM 371  C CG  . PRO A 1 53  ? 175.082 201.519 127.380 1.00 54.23  ? 53  PRO B CG  1 
ATOM 372  C CD  . PRO A 1 53  ? 173.856 201.915 128.135 1.00 54.23  ? 53  PRO B CD  1 
ATOM 373  N N   . ILE A 1 54  ? 174.501 199.599 130.990 1.00 56.35  ? 54  ILE B N   1 
ATOM 374  C CA  . ILE A 1 54  ? 174.762 198.986 132.288 1.00 56.35  ? 54  ILE B CA  1 
ATOM 375  C C   . ILE A 1 54  ? 173.630 198.040 132.674 1.00 56.35  ? 54  ILE B C   1 
ATOM 376  O O   . ILE A 1 54  ? 173.869 196.964 133.236 1.00 56.35  ? 54  ILE B O   1 
ATOM 377  C CB  . ILE A 1 54  ? 175.003 200.068 133.358 1.00 56.35  ? 54  ILE B CB  1 
ATOM 378  C CG1 . ILE A 1 54  ? 175.172 199.434 134.740 1.00 56.35  ? 54  ILE B CG1 1 
ATOM 379  C CG2 . ILE A 1 54  ? 173.885 201.094 133.360 1.00 56.35  ? 54  ILE B CG2 1 
ATOM 380  C CD1 . ILE A 1 54  ? 176.359 198.500 134.844 1.00 56.35  ? 54  ILE B CD1 1 
ATOM 381  N N   . PHE A 1 55  ? 172.387 198.414 132.376 1.00 52.63  ? 55  PHE B N   1 
ATOM 382  C CA  . PHE A 1 55  ? 171.248 197.564 132.699 1.00 52.63  ? 55  PHE B CA  1 
ATOM 383  C C   . PHE A 1 55  ? 170.888 196.606 131.575 1.00 52.63  ? 55  PHE B C   1 
ATOM 384  O O   . PHE A 1 55  ? 170.375 195.515 131.844 1.00 52.63  ? 55  PHE B O   1 
ATOM 385  C CB  . PHE A 1 55  ? 170.027 198.420 133.042 1.00 52.63  ? 55  PHE B CB  1 
ATOM 386  C CG  . PHE A 1 55  ? 170.179 199.212 134.305 1.00 52.63  ? 55  PHE B CG  1 
ATOM 387  C CD1 . PHE A 1 55  ? 169.532 200.424 134.459 1.00 52.63  ? 55  PHE B CD1 1 
ATOM 388  C CD2 . PHE A 1 55  ? 170.970 198.744 135.339 1.00 52.63  ? 55  PHE B CD2 1 
ATOM 389  C CE1 . PHE A 1 55  ? 169.670 201.156 135.620 1.00 52.63  ? 55  PHE B CE1 1 
ATOM 390  C CE2 . PHE A 1 55  ? 171.112 199.471 136.502 1.00 52.63  ? 55  PHE B CE2 1 
ATOM 391  C CZ  . PHE A 1 55  ? 170.461 200.679 136.643 1.00 52.63  ? 55  PHE B CZ  1 
ATOM 392  N N   . GLY A 1 56  ? 171.140 196.985 130.324 1.00 47.23  ? 56  GLY B N   1 
ATOM 393  C CA  . GLY A 1 56  ? 170.766 196.172 129.191 1.00 47.23  ? 56  GLY B CA  1 
ATOM 394  C C   . GLY A 1 56  ? 169.343 196.359 128.718 1.00 47.23  ? 56  GLY B C   1 
ATOM 395  O O   . GLY A 1 56  ? 169.007 195.895 127.621 1.00 47.23  ? 56  GLY B O   1 
ATOM 396  N N   . ILE A 1 57  ? 168.496 197.025 129.503 1.00 47.35  ? 57  ILE B N   1 
ATOM 397  C CA  . ILE A 1 57  ? 167.120 197.264 129.093 1.00 47.35  ? 57  ILE B CA  1 
ATOM 398  C C   . ILE A 1 57  ? 167.096 198.294 127.972 1.00 47.35  ? 57  ILE B C   1 
ATOM 399  O O   . ILE A 1 57  ? 167.817 199.300 128.008 1.00 47.35  ? 57  ILE B O   1 
ATOM 400  C CB  . ILE A 1 57  ? 166.270 197.708 130.298 1.00 47.35  ? 57  ILE B CB  1 
ATOM 401  C CG1 . ILE A 1 57  ? 164.803 197.873 129.896 1.00 47.35  ? 57  ILE B CG1 1 
ATOM 402  C CG2 . ILE A 1 57  ? 166.824 198.980 130.920 1.00 47.35  ? 57  ILE B CG2 1 
ATOM 403  C CD1 . ILE A 1 57  ? 164.061 196.561 129.741 1.00 47.35  ? 57  ILE B CD1 1 
ATOM 404  N N   . ALA A 1 58  ? 166.281 198.034 126.952 1.00 47.43  ? 58  ALA B N   1 
ATOM 405  C CA  . ALA A 1 58  ? 166.232 198.905 125.780 1.00 47.43  ? 58  ALA B CA  1 
ATOM 406  C C   . ALA A 1 58  ? 164.806 198.884 125.240 1.00 47.43  ? 58  ALA B C   1 
ATOM 407  O O   . ALA A 1 58  ? 164.423 197.945 124.536 1.00 47.43  ? 58  ALA B O   1 
ATOM 408  C CB  . ALA A 1 58  ? 167.231 198.458 124.724 1.00 47.43  ? 58  ALA B CB  1 
ATOM 409  N N   . ASN A 1 59  ? 164.035 199.914 125.568 1.00 48.02  ? 59  ASN B N   1 
ATOM 410  C CA  . ASN A 1 59  ? 162.686 200.065 125.047 1.00 48.02  ? 59  ASN B CA  1 
ATOM 411  C C   . ASN A 1 59  ? 162.714 201.067 123.902 1.00 48.02  ? 59  ASN B C   1 
ATOM 412  O O   . ASN A 1 59  ? 163.468 202.043 123.939 1.00 48.02  ? 59  ASN B O   1 
ATOM 413  C CB  . ASN A 1 59  ? 161.719 200.521 126.140 1.00 48.02  ? 59  ASN B CB  1 
ATOM 414  C CG  . ASN A 1 59  ? 160.269 200.410 125.716 1.00 48.02  ? 59  ASN B CG  1 
ATOM 415  O OD1 . ASN A 1 59  ? 159.691 199.325 125.709 1.00 48.02  ? 59  ASN B OD1 1 
ATOM 416  N ND2 . ASN A 1 59  ? 159.673 201.540 125.357 1.00 48.02  ? 59  ASN B ND2 1 
ATOM 417  N N   . TYR A 1 60  ? 161.913 200.810 122.878 1.00 52.46  ? 60  TYR B N   1 
ATOM 418  C CA  . TYR A 1 60  ? 161.962 201.565 121.633 1.00 52.46  ? 60  TYR B CA  1 
ATOM 419  C C   . TYR A 1 60  ? 160.668 202.353 121.459 1.00 52.46  ? 60  TYR B C   1 
ATOM 420  O O   . TYR A 1 60  ? 159.794 202.362 122.329 1.00 52.46  ? 60  TYR B O   1 
ATOM 421  C CB  . TYR A 1 60  ? 162.188 200.634 120.437 1.00 52.46  ? 60  TYR B CB  1 
ATOM 422  C CG  . TYR A 1 60  ? 163.227 199.558 120.664 1.00 52.46  ? 60  TYR B CG  1 
ATOM 423  C CD1 . TYR A 1 60  ? 164.358 199.799 121.431 1.00 52.46  ? 60  TYR B CD1 1 
ATOM 424  C CD2 . TYR A 1 60  ? 163.067 198.292 120.120 1.00 52.46  ? 60  TYR B CD2 1 
ATOM 425  C CE1 . TYR A 1 60  ? 165.296 198.816 121.647 1.00 52.46  ? 60  TYR B CE1 1 
ATOM 426  C CE2 . TYR A 1 60  ? 164.006 197.300 120.328 1.00 52.46  ? 60  TYR B CE2 1 
ATOM 427  C CZ  . TYR A 1 60  ? 165.120 197.570 121.092 1.00 52.46  ? 60  TYR B CZ  1 
ATOM 428  O OH  . TYR A 1 60  ? 166.061 196.589 121.306 1.00 52.46  ? 60  TYR B OH  1 
ATOM 429  N N   . ALA A 1 61  ? 160.554 203.021 120.316 1.00 59.53  ? 61  ALA B N   1 
ATOM 430  C CA  . ALA A 1 61  ? 159.333 203.722 119.951 1.00 59.53  ? 61  ALA B CA  1 
ATOM 431  C C   . ALA A 1 61  ? 158.375 202.760 119.264 1.00 59.53  ? 61  ALA B C   1 
ATOM 432  O O   . ALA A 1 61  ? 158.798 201.886 118.501 1.00 59.53  ? 61  ALA B O   1 
ATOM 433  C CB  . ALA A 1 61  ? 159.636 204.906 119.033 1.00 59.53  ? 61  ALA B CB  1 
ATOM 434  N N   . GLN A 1 62  ? 157.079 202.925 119.541 1.00 68.76  ? 62  GLN B N   1 
ATOM 435  C CA  . GLN A 1 62  ? 156.074 202.042 118.959 1.00 68.76  ? 62  GLN B CA  1 
ATOM 436  C C   . GLN A 1 62  ? 156.074 202.092 117.437 1.00 68.76  ? 62  GLN B C   1 
ATOM 437  O O   . GLN A 1 62  ? 155.660 201.119 116.797 1.00 68.76  ? 62  GLN B O   1 
ATOM 438  C CB  . GLN A 1 62  ? 154.682 202.391 119.496 1.00 68.76  ? 62  GLN B CB  1 
ATOM 439  C CG  . GLN A 1 62  ? 154.075 203.685 118.953 1.00 68.76  ? 62  GLN B CG  1 
ATOM 440  C CD  . GLN A 1 62  ? 154.823 204.935 119.386 1.00 68.76  ? 62  GLN B CD  1 
ATOM 441  O OE1 . GLN A 1 62  ? 155.698 204.885 120.250 1.00 68.76  ? 62  GLN B OE1 1 
ATOM 442  N NE2 . GLN A 1 62  ? 154.477 206.067 118.783 1.00 68.76  ? 62  GLN B NE2 1 
ATOM 443  N N   . LYS A 1 63  ? 156.526 203.199 116.845 1.00 67.84  ? 63  LYS B N   1 
ATOM 444  C CA  . LYS A 1 63  ? 156.644 203.265 115.394 1.00 67.84  ? 63  LYS B CA  1 
ATOM 445  C C   . LYS A 1 63  ? 157.816 202.432 114.891 1.00 67.84  ? 63  LYS B C   1 
ATOM 446  O O   . LYS A 1 63  ? 157.753 201.875 113.790 1.00 67.84  ? 63  LYS B O   1 
ATOM 447  C CB  . LYS A 1 63  ? 156.793 204.720 114.949 1.00 67.84  ? 63  LYS B CB  1 
ATOM 448  C CG  . LYS A 1 63  ? 156.905 204.911 113.446 1.00 67.84  ? 63  LYS B CG  1 
ATOM 449  C CD  . LYS A 1 63  ? 157.518 206.260 113.102 1.00 67.84  ? 63  LYS B CD  1 
ATOM 450  C CE  . LYS A 1 63  ? 156.916 207.373 113.945 1.00 67.84  ? 63  LYS B CE  1 
ATOM 451  N NZ  . LYS A 1 63  ? 155.497 207.639 113.583 1.00 67.84  ? 63  LYS B NZ  1 
ATOM 452  N N   . PHE A 1 64  ? 158.882 202.327 115.682 1.00 68.66  ? 64  PHE B N   1 
ATOM 453  C CA  . PHE A 1 64  ? 160.079 201.597 115.292 1.00 68.66  ? 64  PHE B CA  1 
ATOM 454  C C   . PHE A 1 64  ? 160.248 200.280 116.035 1.00 68.66  ? 64  PHE B C   1 
ATOM 455  O O   . PHE A 1 64  ? 161.234 199.575 115.798 1.00 68.66  ? 64  PHE B O   1 
ATOM 456  C CB  . PHE A 1 64  ? 161.319 202.471 115.514 1.00 68.66  ? 64  PHE B CB  1 
ATOM 457  C CG  . PHE A 1 64  ? 161.404 203.648 114.587 1.00 68.66  ? 64  PHE B CG  1 
ATOM 458  C CD1 . PHE A 1 64  ? 161.678 203.469 113.242 1.00 68.66  ? 64  PHE B CD1 1 
ATOM 459  C CD2 . PHE A 1 64  ? 161.200 204.933 115.060 1.00 68.66  ? 64  PHE B CD2 1 
ATOM 460  C CE1 . PHE A 1 64  ? 161.755 204.551 112.387 1.00 68.66  ? 64  PHE B CE1 1 
ATOM 461  C CE2 . PHE A 1 64  ? 161.273 206.019 114.210 1.00 68.66  ? 64  PHE B CE2 1 
ATOM 462  C CZ  . PHE A 1 64  ? 161.552 205.828 112.872 1.00 68.66  ? 64  PHE B CZ  1 
ATOM 463  N N   . GLN A 1 65  ? 159.322 199.931 116.927 1.00 71.02  ? 65  GLN B N   1 
ATOM 464  C CA  . GLN A 1 65  ? 159.447 198.695 117.689 1.00 71.02  ? 65  GLN B CA  1 
ATOM 465  C C   . GLN A 1 65  ? 159.362 197.491 116.760 1.00 71.02  ? 65  GLN B C   1 
ATOM 466  O O   . GLN A 1 65  ? 158.457 197.396 115.926 1.00 71.02  ? 65  GLN B O   1 
ATOM 467  C CB  . GLN A 1 65  ? 158.358 198.628 118.759 1.00 71.02  ? 65  GLN B CB  1 
ATOM 468  C CG  . GLN A 1 65  ? 158.452 197.420 119.674 1.00 71.02  ? 65  GLN B CG  1 
ATOM 469  C CD  . GLN A 1 65  ? 157.390 197.431 120.755 1.00 71.02  ? 65  GLN B CD  1 
ATOM 470  O OE1 . GLN A 1 65  ? 156.548 198.328 120.805 1.00 71.02  ? 65  GLN B OE1 1 
ATOM 471  N NE2 . GLN A 1 65  ? 157.425 196.432 121.629 1.00 71.02  ? 65  GLN B NE2 1 
ATOM 472  N N   . GLY A 1 66  ? 160.311 196.570 116.906 1.00 72.53  ? 66  GLY B N   1 
ATOM 473  C CA  . GLY A 1 66  ? 160.427 195.454 115.989 1.00 72.53  ? 66  GLY B CA  1 
ATOM 474  C C   . GLY A 1 66  ? 161.168 195.838 114.725 1.00 72.53  ? 66  GLY B C   1 
ATOM 475  O O   . GLY A 1 66  ? 162.015 195.087 114.233 1.00 72.53  ? 66  GLY B O   1 
ATOM 476  N N   . ARG A 1 67  ? 160.845 197.018 114.191 1.00 75.16  ? 67  ARG B N   1 
ATOM 477  C CA  . ARG A 1 67  ? 161.559 197.537 113.031 1.00 75.16  ? 67  ARG B CA  1 
ATOM 478  C C   . ARG A 1 67  ? 163.028 197.784 113.353 1.00 75.16  ? 67  ARG B C   1 
ATOM 479  O O   . ARG A 1 67  ? 163.911 197.477 112.542 1.00 75.16  ? 67  ARG B O   1 
ATOM 480  C CB  . ARG A 1 67  ? 160.889 198.826 112.552 1.00 75.16  ? 67  ARG B CB  1 
ATOM 481  C CG  . ARG A 1 67  ? 161.569 199.518 111.379 1.00 75.16  ? 67  ARG B CG  1 
ATOM 482  C CD  . ARG A 1 67  ? 161.866 198.557 110.241 1.00 75.16  ? 67  ARG B CD  1 
ATOM 483  N NE  . ARG A 1 67  ? 162.571 199.212 109.144 1.00 75.16  ? 67  ARG B NE  1 
ATOM 484  C CZ  . ARG A 1 67  ? 162.025 200.086 108.309 1.00 75.16  ? 67  ARG B CZ  1 
ATOM 485  N NH1 . ARG A 1 67  ? 160.750 200.429 108.402 1.00 75.16  ? 67  ARG B NH1 1 
ATOM 486  N NH2 . ARG A 1 67  ? 162.776 200.628 107.354 1.00 75.16  ? 67  ARG B NH2 1 
ATOM 487  N N   . VAL A 1 68  ? 163.310 198.331 114.534 1.00 69.36  ? 68  VAL B N   1 
ATOM 488  C CA  . VAL A 1 68  ? 164.652 198.753 114.918 1.00 69.36  ? 68  VAL B CA  1 
ATOM 489  C C   . VAL A 1 68  ? 165.033 198.059 116.216 1.00 69.36  ? 68  VAL B C   1 
ATOM 490  O O   . VAL A 1 68  ? 164.246 198.042 117.169 1.00 69.36  ? 68  VAL B O   1 
ATOM 491  C CB  . VAL A 1 68  ? 164.741 200.281 115.085 1.00 69.36  ? 68  VAL B CB  1 
ATOM 492  C CG1 . VAL A 1 68  ? 166.154 200.693 115.460 1.00 69.36  ? 68  VAL B CG1 1 
ATOM 493  C CG2 . VAL A 1 68  ? 164.288 200.983 113.817 1.00 69.36  ? 68  VAL B CG2 1 
ATOM 494  N N   . THR A 1 69  ? 166.237 197.494 116.255 1.00 63.01  ? 69  THR B N   1 
ATOM 495  C CA  . THR A 1 69  ? 166.786 196.907 117.467 1.00 63.01  ? 69  THR B CA  1 
ATOM 496  C C   . THR A 1 69  ? 168.131 197.552 117.769 1.00 63.01  ? 69  THR B C   1 
ATOM 497  O O   . THR A 1 69  ? 168.857 197.971 116.863 1.00 63.01  ? 69  THR B O   1 
ATOM 498  C CB  . THR A 1 69  ? 166.932 195.376 117.352 1.00 63.01  ? 69  THR B CB  1 
ATOM 499  O OG1 . THR A 1 69  ? 167.106 194.811 118.657 1.00 63.01  ? 69  THR B OG1 1 
ATOM 500  C CG2 . THR A 1 69  ? 168.116 194.997 116.476 1.00 63.01  ? 69  THR B CG2 1 
ATOM 501  N N   . ILE A 1 70  ? 168.446 197.651 119.057 1.00 55.39  ? 70  ILE B N   1 
ATOM 502  C CA  . ILE A 1 70  ? 169.640 198.339 119.526 1.00 55.39  ? 70  ILE B CA  1 
ATOM 503  C C   . ILE A 1 70  ? 170.394 197.420 120.478 1.00 55.39  ? 70  ILE B C   1 
ATOM 504  O O   . ILE A 1 70  ? 169.786 196.704 121.282 1.00 55.39  ? 70  ILE B O   1 
ATOM 505  C CB  . ILE A 1 70  ? 169.283 199.684 120.199 1.00 55.39  ? 70  ILE B CB  1 
ATOM 506  C CG1 . ILE A 1 70  ? 170.519 200.562 120.370 1.00 55.39  ? 70  ILE B CG1 1 
ATOM 507  C CG2 . ILE A 1 70  ? 168.618 199.474 121.538 1.00 55.39  ? 70  ILE B CG2 1 
ATOM 508  C CD1 . ILE A 1 70  ? 170.199 201.922 120.935 1.00 55.39  ? 70  ILE B CD1 1 
ATOM 509  N N   . THR A 1 71  ? 171.720 197.403 120.351 1.00 59.93  ? 71  THR B N   1 
ATOM 510  C CA  . THR A 1 71  ? 172.586 196.600 121.205 1.00 59.93  ? 71  THR B CA  1 
ATOM 511  C C   . THR A 1 71  ? 173.721 197.475 121.713 1.00 59.93  ? 71  THR B C   1 
ATOM 512  O O   . THR A 1 71  ? 174.292 198.259 120.949 1.00 59.93  ? 71  THR B O   1 
ATOM 513  C CB  . THR A 1 71  ? 173.159 195.386 120.461 1.00 59.93  ? 71  THR B CB  1 
ATOM 514  O OG1 . THR A 1 71  ? 174.181 195.818 119.554 1.00 59.93  ? 71  THR B OG1 1 
ATOM 515  C CG2 . THR A 1 71  ? 172.072 194.654 119.685 1.00 59.93  ? 71  THR B CG2 1 
ATOM 516  N N   . ALA A 1 72  ? 174.047 197.339 122.994 1.00 63.36  ? 72  ALA B N   1 
ATOM 517  C CA  . ALA A 1 72  ? 175.111 198.112 123.629 1.00 63.36  ? 72  ALA B CA  1 
ATOM 518  C C   . ALA A 1 72  ? 176.225 197.151 124.027 1.00 63.36  ? 72  ALA B C   1 
ATOM 519  O O   . ALA A 1 72  ? 176.133 196.467 125.050 1.00 63.36  ? 72  ALA B O   1 
ATOM 520  C CB  . ALA A 1 72  ? 174.582 198.882 124.834 1.00 63.36  ? 72  ALA B CB  1 
ATOM 521  N N   . ASP A 1 73  ? 177.278 197.102 123.215 1.00 73.91  ? 73  ASP B N   1 
ATOM 522  C CA  . ASP A 1 73  ? 178.424 196.233 123.476 1.00 73.91  ? 73  ASP B CA  1 
ATOM 523  C C   . ASP A 1 73  ? 179.320 196.921 124.498 1.00 73.91  ? 73  ASP B C   1 
ATOM 524  O O   . ASP A 1 73  ? 180.237 197.668 124.155 1.00 73.91  ? 73  ASP B O   1 
ATOM 525  C CB  . ASP A 1 73  ? 179.174 195.928 122.186 1.00 73.91  ? 73  ASP B CB  1 
ATOM 526  C CG  . ASP A 1 73  ? 179.787 194.544 122.184 1.00 73.91  ? 73  ASP B CG  1 
ATOM 527  O OD1 . ASP A 1 73  ? 179.739 193.871 123.235 1.00 73.91  ? 73  ASP B OD1 1 
ATOM 528  O OD2 . ASP A 1 73  ? 180.318 194.128 121.133 1.00 73.91  ? 73  ASP B OD2 1 
ATOM 529  N N   . LYS A 1 74  ? 179.050 196.659 125.779 1.00 74.57  ? 74  LYS B N   1 
ATOM 530  C CA  . LYS A 1 74  ? 179.784 197.309 126.858 1.00 74.57  ? 74  LYS B CA  1 
ATOM 531  C C   . LYS A 1 74  ? 181.246 196.892 126.919 1.00 74.57  ? 74  LYS B C   1 
ATOM 532  O O   . LYS A 1 74  ? 182.032 197.560 127.601 1.00 74.57  ? 74  LYS B O   1 
ATOM 533  C CB  . LYS A 1 74  ? 179.109 197.016 128.199 1.00 74.57  ? 74  LYS B CB  1 
ATOM 534  N N   . SER A 1 75  ? 181.630 195.809 126.239 1.00 78.12  ? 75  SER B N   1 
ATOM 535  C CA  . SER A 1 75  ? 183.026 195.383 126.255 1.00 78.12  ? 75  SER B CA  1 
ATOM 536  C C   . SER A 1 75  ? 183.932 196.435 125.628 1.00 78.12  ? 75  SER B C   1 
ATOM 537  O O   . SER A 1 75  ? 185.017 196.720 126.147 1.00 78.12  ? 75  SER B O   1 
ATOM 538  C CB  . SER A 1 75  ? 183.174 194.045 125.531 1.00 78.12  ? 75  SER B CB  1 
ATOM 539  O OG  . SER A 1 75  ? 182.177 193.127 125.946 1.00 78.12  ? 75  SER B OG  1 
ATOM 540  N N   . THR A 1 76  ? 183.505 197.022 124.511 1.00 72.85  ? 76  THR B N   1 
ATOM 541  C CA  . THR A 1 76  ? 184.265 198.063 123.832 1.00 72.85  ? 76  THR B CA  1 
ATOM 542  C C   . THR A 1 76  ? 183.570 199.419 123.875 1.00 72.85  ? 76  THR B C   1 
ATOM 543  O O   . THR A 1 76  ? 184.036 200.364 123.229 1.00 72.85  ? 76  THR B O   1 
ATOM 544  C CB  . THR A 1 76  ? 184.543 197.654 122.384 1.00 72.85  ? 76  THR B CB  1 
ATOM 545  O OG1 . THR A 1 76  ? 185.325 198.667 121.737 1.00 72.85  ? 76  THR B OG1 1 
ATOM 546  C CG2 . THR A 1 76  ? 183.245 197.445 121.627 1.00 72.85  ? 76  THR B CG2 1 
ATOM 547  N N   . SER A 1 77  ? 182.469 199.534 124.624 1.00 66.00  ? 77  SER B N   1 
ATOM 548  C CA  . SER A 1 77  ? 181.765 200.803 124.828 1.00 66.00  ? 77  SER B CA  1 
ATOM 549  C C   . SER A 1 77  ? 181.344 201.443 123.507 1.00 66.00  ? 77  SER B C   1 
ATOM 550  O O   . SER A 1 77  ? 181.512 202.645 123.299 1.00 66.00  ? 77  SER B O   1 
ATOM 551  C CB  . SER A 1 77  ? 182.612 201.776 125.652 1.00 66.00  ? 77  SER B CB  1 
ATOM 552  O OG  . SER A 1 77  ? 182.822 201.286 126.965 1.00 66.00  ? 77  SER B OG  1 
ATOM 553  N N   . THR A 1 78  ? 180.791 200.635 122.605 1.00 62.51  ? 78  THR B N   1 
ATOM 554  C CA  . THR A 1 78  ? 180.280 201.120 121.322 1.00 62.51  ? 78  THR B CA  1 
ATOM 555  C C   . THR A 1 78  ? 178.854 200.604 121.156 1.00 62.51  ? 78  THR B C   1 
ATOM 556  O O   . THR A 1 78  ? 178.649 199.451 120.765 1.00 62.51  ? 78  THR B O   1 
ATOM 557  C CB  . THR A 1 78  ? 181.159 200.672 120.158 1.00 62.51  ? 78  THR B CB  1 
ATOM 558  O OG1 . THR A 1 78  ? 181.173 199.241 120.093 1.00 62.51  ? 78  THR B OG1 1 
ATOM 559  C CG2 . THR A 1 78  ? 182.583 201.183 120.328 1.00 62.51  ? 78  THR B CG2 1 
ATOM 560  N N   . ALA A 1 79  ? 177.876 201.455 121.452 1.00 59.30  ? 79  ALA B N   1 
ATOM 561  C CA  . ALA A 1 79  ? 176.482 201.083 121.262 1.00 59.30  ? 79  ALA B CA  1 
ATOM 562  C C   . ALA A 1 79  ? 176.172 200.926 119.779 1.00 59.30  ? 79  ALA B C   1 
ATOM 563  O O   . ALA A 1 79  ? 176.594 201.736 118.950 1.00 59.30  ? 79  ALA B O   1 
ATOM 564  C CB  . ALA A 1 79  ? 175.562 202.129 121.886 1.00 59.30  ? 79  ALA B CB  1 
ATOM 565  N N   . TYR A 1 80  ? 175.428 199.875 119.447 1.00 57.74  ? 80  TYR B N   1 
ATOM 566  C CA  . TYR A 1 80  ? 175.113 199.532 118.069 1.00 57.74  ? 80  TYR B CA  1 
ATOM 567  C C   . TYR A 1 80  ? 173.614 199.652 117.837 1.00 57.74  ? 80  TYR B C   1 
ATOM 568  O O   . TYR A 1 80  ? 172.813 199.197 118.658 1.00 57.74  ? 80  TYR B O   1 
ATOM 569  C CB  . TYR A 1 80  ? 175.562 198.105 117.733 1.00 57.74  ? 80  TYR B CB  1 
ATOM 570  C CG  . TYR A 1 80  ? 177.058 197.898 117.703 1.00 57.74  ? 80  TYR B CG  1 
ATOM 571  C CD1 . TYR A 1 80  ? 177.931 198.975 117.662 1.00 57.74  ? 80  TYR B CD1 1 
ATOM 572  C CD2 . TYR A 1 80  ? 177.597 196.619 117.720 1.00 57.74  ? 80  TYR B CD2 1 
ATOM 573  C CE1 . TYR A 1 80  ? 179.298 198.784 117.636 1.00 57.74  ? 80  TYR B CE1 1 
ATOM 574  C CE2 . TYR A 1 80  ? 178.962 196.418 117.694 1.00 57.74  ? 80  TYR B CE2 1 
ATOM 575  C CZ  . TYR A 1 80  ? 179.808 197.504 117.652 1.00 57.74  ? 80  TYR B CZ  1 
ATOM 576  O OH  . TYR A 1 80  ? 181.170 197.309 117.627 1.00 57.74  ? 80  TYR B OH  1 
ATOM 577  N N   . MET A 1 81  ? 173.239 200.258 116.715 1.00 56.14  ? 81  MET B N   1 
ATOM 578  C CA  . MET A 1 81  ? 171.854 200.295 116.270 1.00 56.14  ? 81  MET B CA  1 
ATOM 579  C C   . MET A 1 81  ? 171.733 199.505 114.977 1.00 56.14  ? 81  MET B C   1 
ATOM 580  O O   . MET A 1 81  ? 172.529 199.697 114.052 1.00 56.14  ? 81  MET B O   1 
ATOM 581  C CB  . MET A 1 81  ? 171.367 201.727 116.046 1.00 56.14  ? 81  MET B CB  1 
ATOM 582  C CG  . MET A 1 81  ? 169.906 201.793 115.635 1.00 56.14  ? 81  MET B CG  1 
ATOM 583  S SD  . MET A 1 81  ? 169.278 203.459 115.379 1.00 56.14  ? 81  MET B SD  1 
ATOM 584  C CE  . MET A 1 81  ? 170.103 203.885 113.851 1.00 56.14  ? 81  MET B CE  1 
ATOM 585  N N   . GLU A 1 82  ? 170.744 198.621 114.913 1.00 66.82  ? 82  GLU B N   1 
ATOM 586  C CA  . GLU A 1 82  ? 170.486 197.814 113.727 1.00 66.82  ? 82  GLU B CA  1 
ATOM 587  C C   . GLU A 1 82  ? 169.152 198.246 113.134 1.00 66.82  ? 82  GLU B C   1 
ATOM 588  O O   . GLU A 1 82  ? 168.109 198.126 113.785 1.00 66.82  ? 82  GLU B O   1 
ATOM 589  C CB  . GLU A 1 82  ? 170.484 196.326 114.067 1.00 66.82  ? 82  GLU B CB  1 
ATOM 590  C CG  . GLU A 1 82  ? 170.255 195.419 112.870 1.00 66.82  ? 82  GLU B CG  1 
ATOM 591  C CD  . GLU A 1 82  ? 171.026 194.118 112.970 1.00 66.82  ? 82  GLU B CD  1 
ATOM 592  O OE1 . GLU A 1 82  ? 170.801 193.366 113.942 1.00 66.82  ? 82  GLU B OE1 1 
ATOM 593  O OE2 . GLU A 1 82  ? 171.856 193.848 112.077 1.00 66.82  ? 82  GLU B OE2 1 
ATOM 594  N N   . LEU A 1 83  ? 169.188 198.746 111.903 1.00 74.29  ? 83  LEU B N   1 
ATOM 595  C CA  . LEU A 1 83  ? 167.984 199.153 111.181 1.00 74.29  ? 83  LEU B CA  1 
ATOM 596  C C   . LEU A 1 83  ? 167.579 197.991 110.280 1.00 74.29  ? 83  LEU B C   1 
ATOM 597  O O   . LEU A 1 83  ? 167.949 197.929 109.108 1.00 74.29  ? 83  LEU B O   1 
ATOM 598  C CB  . LEU A 1 83  ? 168.229 200.427 110.383 1.00 74.29  ? 83  LEU B CB  1 
ATOM 599  C CG  . LEU A 1 83  ? 166.992 201.253 110.031 1.00 74.29  ? 83  LEU B CG  1 
ATOM 600  C CD1 . LEU A 1 83  ? 166.548 202.084 111.221 1.00 74.29  ? 83  LEU B CD1 1 
ATOM 601  C CD2 . LEU A 1 83  ? 167.258 202.134 108.822 1.00 74.29  ? 83  LEU B CD2 1 
ATOM 602  N N   . SER A 1 84  ? 166.811 197.062 110.840 1.00 78.14  ? 84  SER B N   1 
ATOM 603  C CA  . SER A 1 84  ? 166.366 195.894 110.093 1.00 78.14  ? 84  SER B CA  1 
ATOM 604  C C   . SER A 1 84  ? 165.372 196.310 109.017 1.00 78.14  ? 84  SER B C   1 
ATOM 605  O O   . SER A 1 84  ? 164.479 197.124 109.268 1.00 78.14  ? 84  SER B O   1 
ATOM 606  C CB  . SER A 1 84  ? 165.731 194.872 111.034 1.00 78.14  ? 84  SER B CB  1 
ATOM 607  O OG  . SER A 1 84  ? 164.592 195.414 111.678 1.00 78.14  ? 84  SER B OG  1 
ATOM 608  N N   . SER A 1 85  ? 165.532 195.745 107.819 1.00 79.00  ? 85  SER B N   1 
ATOM 609  C CA  . SER A 1 85  ? 164.648 196.005 106.682 1.00 79.00  ? 85  SER B CA  1 
ATOM 610  C C   . SER A 1 85  ? 164.551 197.504 106.389 1.00 79.00  ? 85  SER B C   1 
ATOM 611  O O   . SER A 1 85  ? 163.481 198.112 106.446 1.00 79.00  ? 85  SER B O   1 
ATOM 612  C CB  . SER A 1 85  ? 163.261 195.397 106.917 1.00 79.00  ? 85  SER B CB  1 
ATOM 613  O OG  . SER A 1 85  ? 162.550 196.110 107.914 1.00 79.00  ? 85  SER B OG  1 
ATOM 614  N N   . LEU A 1 86  ? 165.702 198.093 106.074 1.00 81.39  ? 86  LEU B N   1 
ATOM 615  C CA  . LEU A 1 86  ? 165.765 199.513 105.742 1.00 81.39  ? 86  LEU B CA  1 
ATOM 616  C C   . LEU A 1 86  ? 165.122 199.740 104.380 1.00 81.39  ? 86  LEU B C   1 
ATOM 617  O O   . LEU A 1 86  ? 165.712 199.414 103.345 1.00 81.39  ? 86  LEU B O   1 
ATOM 618  C CB  . LEU A 1 86  ? 167.212 199.995 105.752 1.00 81.39  ? 86  LEU B CB  1 
ATOM 619  N N   . ARG A 1 87  ? 163.915 200.296 104.375 1.00 78.39  ? 87  ARG B N   1 
ATOM 620  C CA  . ARG A 1 87  ? 163.174 200.529 103.142 1.00 78.39  ? 87  ARG B CA  1 
ATOM 621  C C   . ARG A 1 87  ? 162.303 201.766 103.329 1.00 78.39  ? 87  ARG B C   1 
ATOM 622  O O   . ARG A 1 87  ? 162.492 202.542 104.271 1.00 78.39  ? 87  ARG B O   1 
ATOM 623  C CB  . ARG A 1 87  ? 162.351 199.291 102.762 1.00 78.39  ? 87  ARG B CB  1 
ATOM 624  N N   . SER A 1 88  ? 161.346 201.944 102.421 1.00 76.02  ? 88  SER B N   1 
ATOM 625  C CA  . SER A 1 88  ? 160.402 203.071 102.433 1.00 76.02  ? 88  SER B CA  1 
ATOM 626  C C   . SER A 1 88  ? 161.220 204.357 102.326 1.00 76.02  ? 88  SER B C   1 
ATOM 627  O O   . SER A 1 88  ? 162.038 204.477 101.400 1.00 76.02  ? 88  SER B O   1 
ATOM 628  C CB  . SER A 1 88  ? 159.495 202.963 103.654 1.00 76.02  ? 88  SER B CB  1 
ATOM 629  O OG  . SER A 1 88  ? 158.692 201.797 103.591 1.00 76.02  ? 88  SER B OG  1 
ATOM 630  N N   . GLU A 1 89  ? 161.047 205.323 103.223 1.00 73.13  ? 89  GLU B N   1 
ATOM 631  C CA  . GLU A 1 89  ? 161.776 206.584 103.192 1.00 73.13  ? 89  GLU B CA  1 
ATOM 632  C C   . GLU A 1 89  ? 162.600 206.764 104.460 1.00 73.13  ? 89  GLU B C   1 
ATOM 633  O O   . GLU A 1 89  ? 162.631 207.840 105.060 1.00 73.13  ? 89  GLU B O   1 
ATOM 634  C CB  . GLU A 1 89  ? 160.821 207.760 102.997 1.00 73.13  ? 89  GLU B CB  1 
ATOM 635  N N   . ASP A 1 90  ? 163.284 205.701 104.882 1.00 62.79  ? 90  ASP B N   1 
ATOM 636  C CA  . ASP A 1 90  ? 164.107 205.738 106.083 1.00 62.79  ? 90  ASP B CA  1 
ATOM 637  C C   . ASP A 1 90  ? 165.422 206.478 105.880 1.00 62.79  ? 90  ASP B C   1 
ATOM 638  O O   . ASP A 1 90  ? 166.195 206.601 106.836 1.00 62.79  ? 90  ASP B O   1 
ATOM 639  C CB  . ASP A 1 90  ? 164.388 204.315 106.572 1.00 62.79  ? 90  ASP B CB  1 
ATOM 640  N N   . THR A 1 91  ? 165.697 206.961 104.668 1.00 64.58  ? 91  THR B N   1 
ATOM 641  C CA  . THR A 1 91  ? 166.933 207.684 104.390 1.00 64.58  ? 91  THR B CA  1 
ATOM 642  C C   . THR A 1 91  ? 167.010 208.960 105.217 1.00 64.58  ? 91  THR B C   1 
ATOM 643  O O   . THR A 1 91  ? 166.254 209.908 104.983 1.00 64.58  ? 91  THR B O   1 
ATOM 644  C CB  . THR A 1 91  ? 167.041 208.014 102.900 1.00 64.58  ? 91  THR B CB  1 
ATOM 645  N N   . ALA A 1 92  ? 167.922 208.991 106.182 1.00 57.26  ? 92  ALA B N   1 
ATOM 646  C CA  . ALA A 1 92  ? 168.079 210.136 107.066 1.00 57.26  ? 92  ALA B CA  1 
ATOM 647  C C   . ALA A 1 92  ? 169.525 210.172 107.544 1.00 57.26  ? 92  ALA B C   1 
ATOM 648  O O   . ALA A 1 92  ? 170.384 209.450 107.030 1.00 57.26  ? 92  ALA B O   1 
ATOM 649  C CB  . ALA A 1 92  ? 167.083 210.063 108.229 1.00 57.26  ? 92  ALA B CB  1 
ATOM 650  N N   . VAL A 1 93  ? 169.795 211.015 108.529 1.00 51.42  ? 93  VAL B N   1 
ATOM 651  C CA  . VAL A 1 93  ? 171.130 211.152 109.102 1.00 51.42  ? 93  VAL B CA  1 
ATOM 652  C C   . VAL A 1 93  ? 170.988 210.821 110.584 1.00 51.42  ? 93  VAL B C   1 
ATOM 653  O O   . VAL A 1 93  ? 170.617 211.668 111.401 1.00 51.42  ? 93  VAL B O   1 
ATOM 654  C CB  . VAL A 1 93  ? 171.720 212.546 108.882 1.00 51.42  ? 93  VAL B CB  1 
ATOM 655  C CG1 . VAL A 1 93  ? 173.059 212.669 109.576 1.00 51.42  ? 93  VAL B CG1 1 
ATOM 656  C CG2 . VAL A 1 93  ? 171.854 212.836 107.395 1.00 51.42  ? 93  VAL B CG2 1 
ATOM 657  N N   . TYR A 1 94  ? 171.289 209.575 110.939 1.00 48.65  ? 94  TYR B N   1 
ATOM 658  C CA  . TYR A 1 94  ? 170.975 209.048 112.261 1.00 48.65  ? 94  TYR B CA  1 
ATOM 659  C C   . TYR A 1 94  ? 172.036 209.481 113.266 1.00 48.65  ? 94  TYR B C   1 
ATOM 660  O O   . TYR A 1 94  ? 173.221 209.176 113.097 1.00 48.65  ? 94  TYR B O   1 
ATOM 661  C CB  . TYR A 1 94  ? 170.871 207.524 112.215 1.00 48.65  ? 94  TYR B CB  1 
ATOM 662  C CG  . TYR A 1 94  ? 169.783 206.999 111.301 1.00 48.65  ? 94  TYR B CG  1 
ATOM 663  C CD1 . TYR A 1 94  ? 169.869 207.148 109.923 1.00 48.65  ? 94  TYR B CD1 1 
ATOM 664  C CD2 . TYR A 1 94  ? 168.671 206.354 111.817 1.00 48.65  ? 94  TYR B CD2 1 
ATOM 665  C CE1 . TYR A 1 94  ? 168.881 206.674 109.089 1.00 48.65  ? 94  TYR B CE1 1 
ATOM 666  C CE2 . TYR A 1 94  ? 167.676 205.874 110.988 1.00 48.65  ? 94  TYR B CE2 1 
ATOM 667  C CZ  . TYR A 1 94  ? 167.786 206.037 109.625 1.00 48.65  ? 94  TYR B CZ  1 
ATOM 668  O OH  . TYR A 1 94  ? 166.799 205.561 108.794 1.00 48.65  ? 94  TYR B OH  1 
ATOM 669  N N   . TYR A 1 95  ? 171.610 210.183 114.310 1.00 41.95  ? 95  TYR B N   1 
ATOM 670  C CA  . TYR A 1 95  ? 172.497 210.608 115.380 1.00 41.95  ? 95  TYR B CA  1 
ATOM 671  C C   . TYR A 1 95  ? 172.439 209.617 116.537 1.00 41.95  ? 95  TYR B C   1 
ATOM 672  O O   . TYR A 1 95  ? 171.550 208.770 116.623 1.00 41.95  ? 95  TYR B O   1 
ATOM 673  C CB  . TYR A 1 95  ? 172.126 212.009 115.872 1.00 41.95  ? 95  TYR B CB  1 
ATOM 674  C CG  . TYR A 1 95  ? 172.345 213.118 114.869 1.00 41.95  ? 95  TYR B CG  1 
ATOM 675  C CD1 . TYR A 1 95  ? 172.913 212.864 113.633 1.00 41.95  ? 95  TYR B CD1 1 
ATOM 676  C CD2 . TYR A 1 95  ? 171.982 214.423 115.161 1.00 41.95  ? 95  TYR B CD2 1 
ATOM 677  C CE1 . TYR A 1 95  ? 173.116 213.872 112.721 1.00 41.95  ? 95  TYR B CE1 1 
ATOM 678  C CE2 . TYR A 1 95  ? 172.180 215.438 114.250 1.00 41.95  ? 95  TYR B CE2 1 
ATOM 679  C CZ  . TYR A 1 95  ? 172.747 215.156 113.031 1.00 41.95  ? 95  TYR B CZ  1 
ATOM 680  O OH  . TYR A 1 95  ? 172.950 216.161 112.115 1.00 41.95  ? 95  TYR B OH  1 
ATOM 681  N N   . CYS A 1 96  ? 173.415 209.725 117.432 1.00 36.99  ? 96  CYS B N   1 
ATOM 682  C CA  . CYS A 1 96  ? 173.418 208.988 118.687 1.00 36.99  ? 96  CYS B CA  1 
ATOM 683  C C   . CYS A 1 96  ? 173.687 209.981 119.803 1.00 36.99  ? 96  CYS B C   1 
ATOM 684  O O   . CYS A 1 96  ? 174.592 210.811 119.692 1.00 36.99  ? 96  CYS B O   1 
ATOM 685  C CB  . CYS A 1 96  ? 174.462 207.863 118.689 1.00 36.99  ? 96  CYS B CB  1 
ATOM 686  S SG  . CYS A 1 96  ? 176.191 208.387 118.775 1.00 36.99  ? 96  CYS B SG  1 
ATOM 687  N N   . ALA A 1 97  ? 172.891 209.914 120.864 1.00 32.05  ? 97  ALA B N   1 
ATOM 688  C CA  . ALA A 1 97  ? 172.975 210.895 121.933 1.00 32.05  ? 97  ALA B CA  1 
ATOM 689  C C   . ALA A 1 97  ? 172.815 210.201 123.273 1.00 32.05  ? 97  ALA B C   1 
ATOM 690  O O   . ALA A 1 97  ? 171.944 209.342 123.424 1.00 32.05  ? 97  ALA B O   1 
ATOM 691  C CB  . ALA A 1 97  ? 171.908 211.974 121.759 1.00 32.05  ? 97  ALA B CB  1 
ATOM 692  N N   . ARG A 1 98  ? 173.638 210.579 124.244 1.00 42.47  ? 98  ARG B N   1 
ATOM 693  C CA  . ARG A 1 98  ? 173.654 209.921 125.544 1.00 42.47  ? 98  ARG B CA  1 
ATOM 694  C C   . ARG A 1 98  ? 172.927 210.795 126.563 1.00 42.47  ? 98  ARG B C   1 
ATOM 695  O O   . ARG A 1 98  ? 173.357 211.914 126.859 1.00 42.47  ? 98  ARG B O   1 
ATOM 696  C CB  . ARG A 1 98  ? 175.087 209.613 125.980 1.00 42.47  ? 98  ARG B CB  1 
ATOM 697  C CG  . ARG A 1 98  ? 176.013 210.813 126.085 1.00 42.47  ? 98  ARG B CG  1 
ATOM 698  C CD  . ARG A 1 98  ? 177.422 210.401 126.484 1.00 42.47  ? 98  ARG B CD  1 
ATOM 699  N NE  . ARG A 1 98  ? 177.584 210.241 127.926 1.00 42.47  ? 98  ARG B NE  1 
ATOM 700  C CZ  . ARG A 1 98  ? 177.461 211.210 128.824 1.00 42.47  ? 98  ARG B CZ  1 
ATOM 701  N NH1 . ARG A 1 98  ? 177.189 212.455 128.470 1.00 42.47  ? 98  ARG B NH1 1 
ATOM 702  N NH2 . ARG A 1 98  ? 177.618 210.922 130.113 1.00 42.47  ? 98  ARG B NH2 1 
ATOM 703  N N   . THR A 1 99  ? 171.820 210.293 127.078 1.00 43.95  ? 99  THR B N   1 
ATOM 704  C CA  . THR A 1 99  ? 171.127 210.972 128.162 1.00 43.95  ? 99  THR B CA  1 
ATOM 705  C C   . THR A 1 99  ? 171.779 210.606 129.489 1.00 43.95  ? 99  THR B C   1 
ATOM 706  O O   . THR A 1 99  ? 171.953 209.417 129.776 1.00 43.95  ? 99  THR B O   1 
ATOM 707  C CB  . THR A 1 99  ? 169.651 210.593 128.182 1.00 43.95  ? 99  THR B CB  1 
ATOM 708  N N   . PRO A 1 100 ? 172.168 211.581 130.307 1.00 49.94  ? 100 PRO B N   1 
ATOM 709  C CA  . PRO A 1 100 ? 172.843 211.256 131.567 1.00 49.94  ? 100 PRO B CA  1 
ATOM 710  C C   . PRO A 1 100 ? 171.969 210.396 132.466 1.00 49.94  ? 100 PRO B C   1 
ATOM 711  O O   . PRO A 1 100 ? 170.751 210.569 132.538 1.00 49.94  ? 100 PRO B O   1 
ATOM 712  C CB  . PRO A 1 100 ? 173.107 212.630 132.194 1.00 49.94  ? 100 PRO B CB  1 
ATOM 713  C CG  . PRO A 1 100 ? 173.085 213.580 131.045 1.00 49.94  ? 100 PRO B CG  1 
ATOM 714  C CD  . PRO A 1 100 ? 172.062 213.033 130.096 1.00 49.94  ? 100 PRO B CD  1 
ATOM 715  N N   . LEU A 1 101 ? 172.611 209.455 133.153 1.00 61.45  ? 101 LEU B N   1 
ATOM 716  C CA  . LEU A 1 101 ? 171.943 208.561 134.088 1.00 61.45  ? 101 LEU B CA  1 
ATOM 717  C C   . LEU A 1 101 ? 172.487 208.811 135.486 1.00 61.45  ? 101 LEU B C   1 
ATOM 718  O O   . LEU A 1 101 ? 173.705 208.803 135.694 1.00 61.45  ? 101 LEU B O   1 
ATOM 719  C CB  . LEU A 1 101 ? 172.143 207.094 133.688 1.00 61.45  ? 101 LEU B CB  1 
ATOM 720  C CG  . LEU A 1 101 ? 171.395 206.017 134.482 1.00 61.45  ? 101 LEU B CG  1 
ATOM 721  C CD1 . LEU A 1 101 ? 171.027 204.852 133.583 1.00 61.45  ? 101 LEU B CD1 1 
ATOM 722  C CD2 . LEU A 1 101 ? 172.221 205.519 135.658 1.00 61.45  ? 101 LEU B CD2 1 
ATOM 723  N N   . GLU A 1 102 ? 171.586 209.028 136.438 1.00 70.02  ? 102 GLU B N   1 
ATOM 724  C CA  . GLU A 1 102 ? 171.943 209.219 137.836 1.00 70.02  ? 102 GLU B CA  1 
ATOM 725  C C   . GLU A 1 102 ? 171.424 208.040 138.644 1.00 70.02  ? 102 GLU B C   1 
ATOM 726  O O   . GLU A 1 102 ? 170.234 207.713 138.574 1.00 70.02  ? 102 GLU B O   1 
ATOM 727  C CB  . GLU A 1 102 ? 171.369 210.530 138.377 1.00 70.02  ? 102 GLU B CB  1 
ATOM 728  N N   . MET A 1 103 ? 172.320 207.404 139.403 1.00 73.68  ? 103 MET B N   1 
ATOM 729  C CA  . MET A 1 103 ? 171.985 206.227 140.197 1.00 73.68  ? 103 MET B CA  1 
ATOM 730  C C   . MET A 1 103 ? 171.415 205.128 139.309 1.00 73.68  ? 103 MET B C   1 
ATOM 731  O O   . MET A 1 103 ? 172.167 204.350 138.713 1.00 73.68  ? 103 MET B O   1 
ATOM 732  C CB  . MET A 1 103 ? 171.001 206.584 141.315 1.00 73.68  ? 103 MET B CB  1 
ATOM 733  N N   . ALA A 1 104 ? 170.085 205.053 139.219 1.00 66.41  ? 104 ALA B N   1 
ATOM 734  C CA  . ALA A 1 104 ? 169.440 204.065 138.365 1.00 66.41  ? 104 ALA B CA  1 
ATOM 735  C C   . ALA A 1 104 ? 168.261 204.638 137.587 1.00 66.41  ? 104 ALA B C   1 
ATOM 736  O O   . ALA A 1 104 ? 167.476 203.863 137.028 1.00 66.41  ? 104 ALA B O   1 
ATOM 737  C CB  . ALA A 1 104 ? 168.974 202.862 139.192 1.00 66.41  ? 104 ALA B CB  1 
ATOM 738  N N   . THR A 1 105 ? 168.110 205.959 137.530 1.00 66.73  ? 105 THR B N   1 
ATOM 739  C CA  . THR A 1 105 ? 166.978 206.599 136.871 1.00 66.73  ? 105 THR B CA  1 
ATOM 740  C C   . THR A 1 105 ? 167.471 207.361 135.649 1.00 66.73  ? 105 THR B C   1 
ATOM 741  O O   . THR A 1 105 ? 168.351 208.220 135.762 1.00 66.73  ? 105 THR B O   1 
ATOM 742  C CB  . THR A 1 105 ? 166.253 207.545 137.827 1.00 66.73  ? 105 THR B CB  1 
ATOM 743  O OG1 . THR A 1 105 ? 167.151 208.580 138.247 1.00 66.73  ? 105 THR B OG1 1 
ATOM 744  C CG2 . THR A 1 105 ? 165.762 206.788 139.050 1.00 66.73  ? 105 THR B CG2 1 
ATOM 745  N N   . GLU A 1 106 ? 166.901 207.047 134.489 1.00 57.60  ? 106 GLU B N   1 
ATOM 746  C CA  . GLU A 1 106 ? 167.217 207.782 133.274 1.00 57.60  ? 106 GLU B CA  1 
ATOM 747  C C   . GLU A 1 106 ? 166.640 209.191 133.350 1.00 57.60  ? 106 GLU B C   1 
ATOM 748  O O   . GLU A 1 106 ? 165.586 209.423 133.946 1.00 57.60  ? 106 GLU B O   1 
ATOM 749  C CB  . GLU A 1 106 ? 166.671 207.045 132.051 1.00 57.60  ? 106 GLU B CB  1 
ATOM 750  C CG  . GLU A 1 106 ? 167.171 207.574 130.719 1.00 57.60  ? 106 GLU B CG  1 
ATOM 751  C CD  . GLU A 1 106 ? 166.679 206.748 129.547 1.00 57.60  ? 106 GLU B CD  1 
ATOM 752  O OE1 . GLU A 1 106 ? 165.928 205.777 129.776 1.00 57.60  ? 106 GLU B OE1 1 
ATOM 753  O OE2 . GLU A 1 106 ? 167.044 207.070 128.396 1.00 57.60  ? 106 GLU B OE2 1 
ATOM 754  N N   . GLU A 1 107 ? 167.348 210.143 132.738 1.00 48.72  ? 107 GLU B N   1 
ATOM 755  C CA  . GLU A 1 107 ? 166.999 211.551 132.861 1.00 48.72  ? 107 GLU B CA  1 
ATOM 756  C C   . GLU A 1 107 ? 166.572 212.216 131.561 1.00 48.72  ? 107 GLU B C   1 
ATOM 757  O O   . GLU A 1 107 ? 165.868 213.230 131.619 1.00 48.72  ? 107 GLU B O   1 
ATOM 758  C CB  . GLU A 1 107 ? 168.177 212.342 133.452 1.00 48.72  ? 107 GLU B CB  1 
ATOM 759  N N   . GLY A 1 108 ? 166.961 211.687 130.404 1.00 46.98  ? 108 GLY B N   1 
ATOM 760  C CA  . GLY A 1 108 ? 166.598 212.322 129.150 1.00 46.98  ? 108 GLY B CA  1 
ATOM 761  C C   . GLY A 1 108 ? 167.487 213.514 128.832 1.00 46.98  ? 108 GLY B C   1 
ATOM 762  O O   . GLY A 1 108 ? 168.645 213.585 129.246 1.00 46.98  ? 108 GLY B O   1 
ATOM 763  N N   . TYR A 1 109 ? 166.921 214.466 128.088 1.00 45.10  ? 109 TYR B N   1 
ATOM 764  C CA  . TYR A 1 109 ? 167.608 215.680 127.635 1.00 45.10  ? 109 TYR B CA  1 
ATOM 765  C C   . TYR A 1 109 ? 168.997 215.357 127.071 1.00 45.10  ? 109 TYR B C   1 
ATOM 766  O O   . TYR A 1 109 ? 170.036 215.653 127.655 1.00 45.10  ? 109 TYR B O   1 
ATOM 767  C CB  . TYR A 1 109 ? 167.650 216.755 128.734 1.00 45.10  ? 109 TYR B CB  1 
ATOM 768  C CG  . TYR A 1 109 ? 168.322 216.410 130.051 1.00 45.10  ? 109 TYR B CG  1 
ATOM 769  C CD1 . TYR A 1 109 ? 167.593 215.863 131.098 1.00 45.10  ? 109 TYR B CD1 1 
ATOM 770  C CD2 . TYR A 1 109 ? 169.665 216.690 130.272 1.00 45.10  ? 109 TYR B CD2 1 
ATOM 771  C CE1 . TYR A 1 109 ? 168.191 215.565 132.307 1.00 45.10  ? 109 TYR B CE1 1 
ATOM 772  C CE2 . TYR A 1 109 ? 170.272 216.390 131.475 1.00 45.10  ? 109 TYR B CE2 1 
ATOM 773  C CZ  . TYR A 1 109 ? 169.531 215.830 132.490 1.00 45.10  ? 109 TYR B CZ  1 
ATOM 774  O OH  . TYR A 1 109 ? 170.128 215.534 133.694 1.00 45.10  ? 109 TYR B OH  1 
ATOM 775  N N   . PHE A 1 110 ? 168.969 214.702 125.908 1.00 37.29  ? 110 PHE B N   1 
ATOM 776  C CA  . PHE A 1 110 ? 170.177 214.343 125.171 1.00 37.29  ? 110 PHE B CA  1 
ATOM 777  C C   . PHE A 1 110 ? 171.128 215.527 125.054 1.00 37.29  ? 110 PHE B C   1 
ATOM 778  O O   . PHE A 1 110 ? 170.798 216.524 124.405 1.00 37.29  ? 110 PHE B O   1 
ATOM 779  C CB  . PHE A 1 110 ? 169.823 213.849 123.769 1.00 37.29  ? 110 PHE B CB  1 
ATOM 780  C CG  . PHE A 1 110 ? 168.666 212.895 123.725 1.00 37.29  ? 110 PHE B CG  1 
ATOM 781  C CD1 . PHE A 1 110 ? 168.502 211.927 124.698 1.00 37.29  ? 110 PHE B CD1 1 
ATOM 782  C CD2 . PHE A 1 110 ? 167.752 212.955 122.689 1.00 37.29  ? 110 PHE B CD2 1 
ATOM 783  C CE1 . PHE A 1 110 ? 167.437 211.054 124.648 1.00 37.29  ? 110 PHE B CE1 1 
ATOM 784  C CE2 . PHE A 1 110 ? 166.691 212.082 122.631 1.00 37.29  ? 110 PHE B CE2 1 
ATOM 785  C CZ  . PHE A 1 110 ? 166.534 211.128 123.610 1.00 37.29  ? 110 PHE B CZ  1 
ATOM 786  N N   . ASP A 1 111 ? 172.311 215.429 125.658 1.00 39.76  ? 111 ASP B N   1 
ATOM 787  C CA  . ASP A 1 111 ? 173.246 216.547 125.693 1.00 39.76  ? 111 ASP B CA  1 
ATOM 788  C C   . ASP A 1 111 ? 174.446 216.353 124.772 1.00 39.76  ? 111 ASP B C   1 
ATOM 789  O O   . ASP A 1 111 ? 174.795 217.260 124.011 1.00 39.76  ? 111 ASP B O   1 
ATOM 790  C CB  . ASP A 1 111 ? 173.721 216.791 127.131 1.00 39.76  ? 111 ASP B CB  1 
ATOM 791  C CG  . ASP A 1 111 ? 174.291 215.547 127.779 1.00 39.76  ? 111 ASP B CG  1 
ATOM 792  O OD1 . ASP A 1 111 ? 174.341 214.497 127.108 1.00 39.76  ? 111 ASP B OD1 1 
ATOM 793  O OD2 . ASP A 1 111 ? 174.685 215.617 128.962 1.00 39.76  ? 111 ASP B OD2 1 
ATOM 794  N N   . TYR A 1 112 ? 175.089 215.191 124.826 1.00 40.67  ? 112 TYR B N   1 
ATOM 795  C CA  . TYR A 1 112 ? 176.274 214.912 124.026 1.00 40.67  ? 112 TYR B CA  1 
ATOM 796  C C   . TYR A 1 112 ? 175.881 214.033 122.847 1.00 40.67  ? 112 TYR B C   1 
ATOM 797  O O   . TYR A 1 112 ? 175.309 212.956 123.034 1.00 40.67  ? 112 TYR B O   1 
ATOM 798  C CB  . TYR A 1 112 ? 177.351 214.247 124.879 1.00 40.67  ? 112 TYR B CB  1 
ATOM 799  C CG  . TYR A 1 112 ? 178.092 215.225 125.759 1.00 40.67  ? 112 TYR B CG  1 
ATOM 800  C CD1 . TYR A 1 112 ? 178.909 216.203 125.209 1.00 40.67  ? 112 TYR B CD1 1 
ATOM 801  C CD2 . TYR A 1 112 ? 177.942 215.197 127.137 1.00 40.67  ? 112 TYR B CD2 1 
ATOM 802  C CE1 . TYR A 1 112 ? 179.581 217.105 126.012 1.00 40.67  ? 112 TYR B CE1 1 
ATOM 803  C CE2 . TYR A 1 112 ? 178.608 216.093 127.946 1.00 40.67  ? 112 TYR B CE2 1 
ATOM 804  C CZ  . TYR A 1 112 ? 179.424 217.046 127.380 1.00 40.67  ? 112 TYR B CZ  1 
ATOM 805  O OH  . TYR A 1 112 ? 180.085 217.941 128.189 1.00 40.67  ? 112 TYR B OH  1 
ATOM 806  N N   . TRP A 1 113 ? 176.195 214.492 121.642 1.00 34.64  ? 113 TRP B N   1 
ATOM 807  C CA  . TRP A 1 113 ? 175.692 213.904 120.413 1.00 34.64  ? 113 TRP B CA  1 
ATOM 808  C C   . TRP A 1 113 ? 176.849 213.444 119.537 1.00 34.64  ? 113 TRP B C   1 
ATOM 809  O O   . TRP A 1 113 ? 177.991 213.883 119.690 1.00 34.64  ? 113 TRP B O   1 
ATOM 810  C CB  . TRP A 1 113 ? 174.829 214.913 119.648 1.00 34.64  ? 113 TRP B CB  1 
ATOM 811  C CG  . TRP A 1 113 ? 173.504 215.185 120.284 1.00 34.64  ? 113 TRP B CG  1 
ATOM 812  C CD1 . TRP A 1 113 ? 173.286 215.729 121.515 1.00 34.64  ? 113 TRP B CD1 1 
ATOM 813  C CD2 . TRP A 1 113 ? 172.213 214.952 119.714 1.00 34.64  ? 113 TRP B CD2 1 
ATOM 814  N NE1 . TRP A 1 113 ? 171.939 215.836 121.752 1.00 34.64  ? 113 TRP B NE1 1 
ATOM 815  C CE2 . TRP A 1 113 ? 171.258 215.368 120.661 1.00 34.64  ? 113 TRP B CE2 1 
ATOM 816  C CE3 . TRP A 1 113 ? 171.771 214.426 118.498 1.00 34.64  ? 113 TRP B CE3 1 
ATOM 817  C CZ2 . TRP A 1 113 ? 169.891 215.274 120.429 1.00 34.64  ? 113 TRP B CZ2 1 
ATOM 818  C CZ3 . TRP A 1 113 ? 170.413 214.336 118.270 1.00 34.64  ? 113 TRP B CZ3 1 
ATOM 819  C CH2 . TRP A 1 113 ? 169.489 214.757 119.230 1.00 34.64  ? 113 TRP B CH2 1 
ATOM 820  N N   . GLY A 1 114 ? 176.540 212.542 118.607 1.00 39.04  ? 114 GLY B N   1 
ATOM 821  C CA  . GLY A 1 114 ? 177.480 212.134 117.586 1.00 39.04  ? 114 GLY B CA  1 
ATOM 822  C C   . GLY A 1 114 ? 177.457 213.079 116.402 1.00 39.04  ? 114 GLY B C   1 
ATOM 823  O O   . GLY A 1 114 ? 176.816 214.131 116.418 1.00 39.04  ? 114 GLY B O   1 
ATOM 824  N N   . GLN A 1 115 ? 178.172 212.688 115.349 1.00 49.07  ? 115 GLN B N   1 
ATOM 825  C CA  . GLN A 1 115 ? 178.205 213.495 114.135 1.00 49.07  ? 115 GLN B CA  1 
ATOM 826  C C   . GLN A 1 115 ? 177.183 213.062 113.095 1.00 49.07  ? 115 GLN B C   1 
ATOM 827  O O   . GLN A 1 115 ? 176.770 213.887 112.273 1.00 49.07  ? 115 GLN B O   1 
ATOM 828  C CB  . GLN A 1 115 ? 179.608 213.487 113.514 1.00 49.07  ? 115 GLN B CB  1 
ATOM 829  C CG  . GLN A 1 115 ? 180.046 212.168 112.910 1.00 49.07  ? 115 GLN B CG  1 
ATOM 830  C CD  . GLN A 1 115 ? 180.642 211.223 113.933 1.00 49.07  ? 115 GLN B CD  1 
ATOM 831  O OE1 . GLN A 1 115 ? 180.470 211.400 115.137 1.00 49.07  ? 115 GLN B OE1 1 
ATOM 832  N NE2 . GLN A 1 115 ? 181.357 210.214 113.455 1.00 49.07  ? 115 GLN B NE2 1 
ATOM 833  N N   . GLY A 1 116 ? 176.767 211.798 113.102 1.00 50.71  ? 116 GLY B N   1 
ATOM 834  C CA  . GLY A 1 116 ? 175.679 211.370 112.245 1.00 50.71  ? 116 GLY B CA  1 
ATOM 835  C C   . GLY A 1 116 ? 176.092 210.611 111.003 1.00 50.71  ? 116 GLY B C   1 
ATOM 836  O O   . GLY A 1 116 ? 176.768 211.160 110.129 1.00 50.71  ? 116 GLY B O   1 
ATOM 837  N N   . THR A 1 117 ? 175.685 209.347 110.910 1.00 55.52  ? 117 THR B N   1 
ATOM 838  C CA  . THR A 1 117 ? 175.908 208.546 109.709 1.00 55.52  ? 117 THR B CA  1 
ATOM 839  C C   . THR A 1 117 ? 174.856 208.928 108.678 1.00 55.52  ? 117 THR B C   1 
ATOM 840  O O   . THR A 1 117 ? 173.691 208.544 108.788 1.00 55.52  ? 117 THR B O   1 
ATOM 841  C CB  . THR A 1 117 ? 175.841 207.057 110.027 1.00 55.52  ? 117 THR B CB  1 
ATOM 842  O OG1 . THR A 1 117 ? 174.539 206.733 110.530 1.00 55.52  ? 117 THR B OG1 1 
ATOM 843  C CG2 . THR A 1 117 ? 176.890 206.681 111.055 1.00 55.52  ? 117 THR B CG2 1 
ATOM 844  N N   . LEU A 1 118 ? 175.271 209.674 107.655 1.00 63.06  ? 118 LEU B N   1 
ATOM 845  C CA  . LEU A 1 118 ? 174.343 210.139 106.634 1.00 63.06  ? 118 LEU B CA  1 
ATOM 846  C C   . LEU A 1 118 ? 173.891 208.980 105.757 1.00 63.06  ? 118 LEU B C   1 
ATOM 847  O O   . LEU A 1 118 ? 174.298 208.876 104.595 1.00 63.06  ? 118 LEU B O   1 
ATOM 848  C CB  . LEU A 1 118 ? 174.988 211.233 105.781 1.00 63.06  ? 118 LEU B CB  1 
ATOM 849  N N   . VAL A 1 119 ? 173.044 208.109 106.303 1.00 64.40  ? 119 VAL B N   1 
ATOM 850  C CA  . VAL A 1 119 ? 172.561 206.944 105.573 1.00 64.40  ? 119 VAL B CA  1 
ATOM 851  C C   . VAL A 1 119 ? 171.594 207.414 104.497 1.00 64.40  ? 119 VAL B C   1 
ATOM 852  O O   . VAL A 1 119 ? 170.421 207.687 104.776 1.00 64.40  ? 119 VAL B O   1 
ATOM 853  C CB  . VAL A 1 119 ? 171.892 205.931 106.519 1.00 64.40  ? 119 VAL B CB  1 
ATOM 854  C CG1 . VAL A 1 119 ? 171.410 204.717 105.745 1.00 64.40  ? 119 VAL B CG1 1 
ATOM 855  C CG2 . VAL A 1 119 ? 172.851 205.522 107.625 1.00 64.40  ? 119 VAL B CG2 1 
ATOM 856  N N   . THR A 1 120 ? 172.077 207.511 103.262 1.00 77.35  ? 120 THR B N   1 
ATOM 857  C CA  . THR A 1 120 ? 171.293 208.013 102.142 1.00 77.35  ? 120 THR B CA  1 
ATOM 858  C C   . THR A 1 120 ? 171.435 207.066 100.961 1.00 77.35  ? 120 THR B C   1 
ATOM 859  O O   . THR A 1 120 ? 172.538 206.589 100.673 1.00 77.35  ? 120 THR B O   1 
ATOM 860  C CB  . THR A 1 120 ? 171.737 209.425 101.738 1.00 77.35  ? 120 THR B CB  1 
ATOM 861  O OG1 . THR A 1 120 ? 173.124 209.409 101.381 1.00 77.35  ? 120 THR B OG1 1 
ATOM 862  C CG2 . THR A 1 120 ? 171.522 210.409 102.881 1.00 77.35  ? 120 THR B CG2 1 
ATOM 863  N N   . VAL A 1 121 ? 170.324 206.795 100.285 1.00 89.93  ? 121 VAL B N   1 
ATOM 864  C CA  . VAL A 1 121 ? 170.319 205.961 99.086  1.00 89.93  ? 121 VAL B CA  1 
ATOM 865  C C   . VAL A 1 121 ? 170.356 206.924 97.903  1.00 89.93  ? 121 VAL B C   1 
ATOM 866  O O   . VAL A 1 121 ? 169.323 207.327 97.365  1.00 89.93  ? 121 VAL B O   1 
ATOM 867  C CB  . VAL A 1 121 ? 169.110 205.029 99.041  1.00 89.93  ? 121 VAL B CB  1 
ATOM 868  C CG1 . VAL A 1 121 ? 169.197 204.099 97.837  1.00 89.93  ? 121 VAL B CG1 1 
ATOM 869  C CG2 . VAL A 1 121 ? 169.004 204.235 100.335 1.00 89.93  ? 121 VAL B CG2 1 
ATOM 870  N N   . SER A 1 122 ? 171.565 207.297 97.492  1.00 100.06 ? 122 SER B N   1 
ATOM 871  C CA  . SER A 1 122 ? 171.745 208.223 96.383  1.00 100.06 ? 122 SER B CA  1 
ATOM 872  C C   . SER A 1 122 ? 173.174 208.113 95.873  1.00 100.06 ? 122 SER B C   1 
ATOM 873  O O   . SER A 1 122 ? 174.082 207.727 96.614  1.00 100.06 ? 122 SER B O   1 
ATOM 874  C CB  . SER A 1 122 ? 171.436 209.667 96.798  1.00 100.06 ? 122 SER B CB  1 
ATOM 875  O OG  . SER A 1 122 ? 171.620 210.560 95.713  1.00 100.06 ? 122 SER B OG  1 
ATOM 876  N N   . SER A 1 123 ? 173.357 208.454 94.595  1.00 107.00 ? 123 SER B N   1 
ATOM 877  C CA  . SER A 1 123 ? 174.690 208.413 94.002  1.00 107.00 ? 123 SER B CA  1 
ATOM 878  C C   . SER A 1 123 ? 175.619 209.431 94.653  1.00 107.00 ? 123 SER B C   1 
ATOM 879  O O   . SER A 1 123 ? 176.791 209.130 94.911  1.00 107.00 ? 123 SER B O   1 
ATOM 880  C CB  . SER A 1 123 ? 174.600 208.654 92.495  1.00 107.00 ? 123 SER B CB  1 
ATOM 881  O OG  . SER A 1 123 ? 174.152 209.969 92.215  1.00 107.00 ? 123 SER B OG  1 
ATOM 882  N N   . ALA A 1 124 ? 175.114 210.633 94.923  1.00 106.12 ? 124 ALA B N   1 
ATOM 883  C CA  . ALA A 1 124 ? 175.887 211.710 95.542  1.00 106.12 ? 124 ALA B CA  1 
ATOM 884  C C   . ALA A 1 124 ? 177.167 212.010 94.766  1.00 106.12 ? 124 ALA B C   1 
ATOM 885  O O   . ALA A 1 124 ? 177.687 213.125 94.816  1.00 106.12 ? 124 ALA B O   1 
ATOM 886  C CB  . ALA A 1 124 ? 176.212 211.368 96.992  1.00 106.12 ? 124 ALA B CB  1 
ATOM 887  N N   . ASP B 2 1   ? 153.669 210.027 121.550 1.00 59.74  ? 1   ASP C N   1 
ATOM 888  C CA  . ASP B 2 1   ? 152.355 210.372 121.022 1.00 59.74  ? 1   ASP C CA  1 
ATOM 889  C C   . ASP B 2 1   ? 151.968 211.794 121.409 1.00 59.74  ? 1   ASP C C   1 
ATOM 890  O O   . ASP B 2 1   ? 150.833 212.219 121.194 1.00 59.74  ? 1   ASP C O   1 
ATOM 891  C CB  . ASP B 2 1   ? 151.300 209.384 121.522 1.00 59.74  ? 1   ASP C CB  1 
ATOM 892  N N   . ILE B 2 2   ? 152.919 212.524 121.982 1.00 61.07  ? 2   ILE C N   1 
ATOM 893  C CA  . ILE B 2 2   ? 152.705 213.908 122.399 1.00 61.07  ? 2   ILE C CA  1 
ATOM 894  C C   . ILE B 2 2   ? 153.237 214.781 121.268 1.00 61.07  ? 2   ILE C C   1 
ATOM 895  O O   . ILE B 2 2   ? 154.437 215.031 121.155 1.00 61.07  ? 2   ILE C O   1 
ATOM 896  C CB  . ILE B 2 2   ? 153.380 214.212 123.734 1.00 61.07  ? 2   ILE C CB  1 
ATOM 897  C CG1 . ILE B 2 2   ? 152.803 213.319 124.832 1.00 61.07  ? 2   ILE C CG1 1 
ATOM 898  C CG2 . ILE B 2 2   ? 153.208 215.675 124.098 1.00 61.07  ? 2   ILE C CG2 1 
ATOM 899  C CD1 . ILE B 2 2   ? 153.412 213.554 126.186 1.00 61.07  ? 2   ILE C CD1 1 
ATOM 900  N N   . GLN B 2 3   ? 152.329 215.255 120.420 1.00 62.50  ? 3   GLN C N   1 
ATOM 901  C CA  . GLN B 2 3   ? 152.704 216.039 119.249 1.00 62.50  ? 3   GLN C CA  1 
ATOM 902  C C   . GLN B 2 3   ? 152.931 217.485 119.673 1.00 62.50  ? 3   GLN C C   1 
ATOM 903  O O   . GLN B 2 3   ? 151.980 218.201 120.002 1.00 62.50  ? 3   GLN C O   1 
ATOM 904  C CB  . GLN B 2 3   ? 151.621 215.932 118.178 1.00 62.50  ? 3   GLN C CB  1 
ATOM 905  C CG  . GLN B 2 3   ? 151.996 216.521 116.827 1.00 62.50  ? 3   GLN C CG  1 
ATOM 906  C CD  . GLN B 2 3   ? 151.670 217.995 116.716 1.00 62.50  ? 3   GLN C CD  1 
ATOM 907  O OE1 . GLN B 2 3   ? 150.736 218.486 117.351 1.00 62.50  ? 3   GLN C OE1 1 
ATOM 908  N NE2 . GLN B 2 3   ? 152.437 218.711 115.902 1.00 62.50  ? 3   GLN C NE2 1 
ATOM 909  N N   . MET B 2 4   ? 154.190 217.916 119.668 1.00 61.07  ? 4   MET C N   1 
ATOM 910  C CA  . MET B 2 4   ? 154.551 219.272 120.056 1.00 61.07  ? 4   MET C CA  1 
ATOM 911  C C   . MET B 2 4   ? 154.483 220.208 118.856 1.00 61.07  ? 4   MET C C   1 
ATOM 912  O O   . MET B 2 4   ? 154.605 219.784 117.704 1.00 61.07  ? 4   MET C O   1 
ATOM 913  C CB  . MET B 2 4   ? 155.956 219.311 120.659 1.00 61.07  ? 4   MET C CB  1 
ATOM 914  C CG  . MET B 2 4   ? 156.258 218.172 121.614 1.00 61.07  ? 4   MET C CG  1 
ATOM 915  S SD  . MET B 2 4   ? 155.621 218.463 123.271 1.00 61.07  ? 4   MET C SD  1 
ATOM 916  C CE  . MET B 2 4   ? 157.019 219.270 124.043 1.00 61.07  ? 4   MET C CE  1 
ATOM 917  N N   . THR B 2 5   ? 154.286 221.493 119.139 1.00 60.81  ? 5   THR C N   1 
ATOM 918  C CA  . THR B 2 5   ? 154.243 222.517 118.103 1.00 60.81  ? 5   THR C CA  1 
ATOM 919  C C   . THR B 2 5   ? 154.736 223.832 118.685 1.00 60.81  ? 5   THR C C   1 
ATOM 920  O O   . THR B 2 5   ? 154.241 224.277 119.724 1.00 60.81  ? 5   THR C O   1 
ATOM 921  C CB  . THR B 2 5   ? 152.827 222.681 117.539 1.00 60.81  ? 5   THR C CB  1 
ATOM 922  O OG1 . THR B 2 5   ? 152.392 221.441 116.969 1.00 60.81  ? 5   THR C OG1 1 
ATOM 923  C CG2 . THR B 2 5   ? 152.803 223.755 116.464 1.00 60.81  ? 5   THR C CG2 1 
ATOM 924  N N   . GLN B 2 6   ? 155.706 224.451 118.014 1.00 56.62  ? 6   GLN C N   1 
ATOM 925  C CA  . GLN B 2 6   ? 156.297 225.695 118.480 1.00 56.62  ? 6   GLN C CA  1 
ATOM 926  C C   . GLN B 2 6   ? 155.554 226.894 117.894 1.00 56.62  ? 6   GLN C C   1 
ATOM 927  O O   . GLN B 2 6   ? 154.470 226.772 117.317 1.00 56.62  ? 6   GLN C O   1 
ATOM 928  C CB  . GLN B 2 6   ? 157.778 225.767 118.116 1.00 56.62  ? 6   GLN C CB  1 
ATOM 929  C CG  . GLN B 2 6   ? 158.636 224.638 118.633 1.00 56.62  ? 6   GLN C CG  1 
ATOM 930  C CD  . GLN B 2 6   ? 159.725 224.260 117.658 1.00 56.62  ? 6   GLN C CD  1 
ATOM 931  O OE1 . GLN B 2 6   ? 160.565 225.084 117.300 1.00 56.62  ? 6   GLN C OE1 1 
ATOM 932  N NE2 . GLN B 2 6   ? 159.723 223.009 117.226 1.00 56.62  ? 6   GLN C NE2 1 
ATOM 933  N N   . SER B 2 7   ? 156.148 228.076 118.050 1.00 62.35  ? 7   SER C N   1 
ATOM 934  C CA  . SER B 2 7   ? 155.681 229.279 117.391 1.00 62.35  ? 7   SER C CA  1 
ATOM 935  C C   . SER B 2 7   ? 155.989 229.178 115.900 1.00 62.35  ? 7   SER C C   1 
ATOM 936  O O   . SER B 2 7   ? 156.766 228.319 115.477 1.00 62.35  ? 7   SER C O   1 
ATOM 937  C CB  . SER B 2 7   ? 156.345 230.508 118.009 1.00 62.35  ? 7   SER C CB  1 
ATOM 938  O OG  . SER B 2 7   ? 157.724 230.553 117.688 1.00 62.35  ? 7   SER C OG  1 
ATOM 939  N N   . PRO B 2 8   ? 155.370 230.023 115.073 1.00 65.07  ? 8   PRO C N   1 
ATOM 940  C CA  . PRO B 2 8   ? 155.645 229.974 113.633 1.00 65.07  ? 8   PRO C CA  1 
ATOM 941  C C   . PRO B 2 8   ? 157.135 230.062 113.336 1.00 65.07  ? 8   PRO C C   1 
ATOM 942  O O   . PRO B 2 8   ? 157.873 230.823 113.965 1.00 65.07  ? 8   PRO C O   1 
ATOM 943  C CB  . PRO B 2 8   ? 154.888 231.191 113.095 1.00 65.07  ? 8   PRO C CB  1 
ATOM 944  C CG  . PRO B 2 8   ? 153.720 231.310 114.008 1.00 65.07  ? 8   PRO C CG  1 
ATOM 945  C CD  . PRO B 2 8   ? 154.199 230.869 115.374 1.00 65.07  ? 8   PRO C CD  1 
ATOM 946  N N   . SER B 2 9   ? 157.572 229.251 112.368 1.00 69.20  ? 9   SER C N   1 
ATOM 947  C CA  . SER B 2 9   ? 158.998 229.099 112.097 1.00 69.20  ? 9   SER C CA  1 
ATOM 948  C C   . SER B 2 9   ? 159.621 230.399 111.603 1.00 69.20  ? 9   SER C C   1 
ATOM 949  O O   . SER B 2 9   ? 160.769 230.711 111.941 1.00 69.20  ? 9   SER C O   1 
ATOM 950  C CB  . SER B 2 9   ? 159.216 227.981 111.079 1.00 69.20  ? 9   SER C CB  1 
ATOM 951  O OG  . SER B 2 9   ? 158.896 228.418 109.770 1.00 69.20  ? 9   SER C OG  1 
ATOM 952  N N   . SER B 2 10  ? 158.888 231.167 110.803 1.00 73.71  ? 10  SER C N   1 
ATOM 953  C CA  . SER B 2 10  ? 159.435 232.376 110.202 1.00 73.71  ? 10  SER C CA  1 
ATOM 954  C C   . SER B 2 10  ? 159.678 233.422 111.283 1.00 73.71  ? 10  SER C C   1 
ATOM 955  O O   . SER B 2 10  ? 158.736 234.065 111.758 1.00 73.71  ? 10  SER C O   1 
ATOM 956  C CB  . SER B 2 10  ? 158.486 232.914 109.133 1.00 73.71  ? 10  SER C CB  1 
ATOM 957  O OG  . SER B 2 10  ? 159.089 233.960 108.393 1.00 73.71  ? 10  SER C OG  1 
ATOM 958  N N   . VAL B 2 11  ? 160.941 233.588 111.672 1.00 65.59  ? 11  VAL C N   1 
ATOM 959  C CA  . VAL B 2 11  ? 161.350 234.583 112.656 1.00 65.59  ? 11  VAL C CA  1 
ATOM 960  C C   . VAL B 2 11  ? 162.504 235.382 112.068 1.00 65.59  ? 11  VAL C C   1 
ATOM 961  O O   . VAL B 2 11  ? 163.490 234.801 111.603 1.00 65.59  ? 11  VAL C O   1 
ATOM 962  C CB  . VAL B 2 11  ? 161.764 233.938 113.991 1.00 65.59  ? 11  VAL C CB  1 
ATOM 963  C CG1 . VAL B 2 11  ? 162.092 235.011 115.015 1.00 65.59  ? 11  VAL C CG1 1 
ATOM 964  C CG2 . VAL B 2 11  ? 160.667 233.024 114.506 1.00 65.59  ? 11  VAL C CG2 1 
ATOM 965  N N   . SER B 2 12  ? 162.383 236.707 112.088 1.00 69.09  ? 12  SER C N   1 
ATOM 966  C CA  . SER B 2 12  ? 163.380 237.602 111.509 1.00 69.09  ? 12  SER C CA  1 
ATOM 967  C C   . SER B 2 12  ? 163.903 238.537 112.594 1.00 69.09  ? 12  SER C C   1 
ATOM 968  O O   . SER B 2 12  ? 163.182 239.428 113.055 1.00 69.09  ? 12  SER C O   1 
ATOM 969  C CB  . SER B 2 12  ? 162.790 238.396 110.346 1.00 69.09  ? 12  SER C CB  1 
ATOM 970  O OG  . SER B 2 12  ? 163.666 239.437 109.947 1.00 69.09  ? 12  SER C OG  1 
ATOM 971  N N   . ALA B 2 13  ? 165.155 238.333 112.995 1.00 67.60  ? 13  ALA C N   1 
ATOM 972  C CA  . ALA B 2 13  ? 165.841 239.214 113.930 1.00 67.60  ? 13  ALA C CA  1 
ATOM 973  C C   . ALA B 2 13  ? 167.263 239.424 113.436 1.00 67.60  ? 13  ALA C C   1 
ATOM 974  O O   . ALA B 2 13  ? 167.989 238.453 113.202 1.00 67.60  ? 13  ALA C O   1 
ATOM 975  C CB  . ALA B 2 13  ? 165.841 238.633 115.347 1.00 67.60  ? 13  ALA C CB  1 
ATOM 976  N N   . SER B 2 14  ? 167.659 240.686 113.282 1.00 65.24  ? 14  SER C N   1 
ATOM 977  C CA  . SER B 2 14  ? 168.942 240.994 112.661 1.00 65.24  ? 14  SER C CA  1 
ATOM 978  C C   . SER B 2 14  ? 170.110 240.630 113.569 1.00 65.24  ? 14  SER C C   1 
ATOM 979  O O   . SER B 2 14  ? 170.903 239.743 113.238 1.00 65.24  ? 14  SER C O   1 
ATOM 980  C CB  . SER B 2 14  ? 169.008 242.477 112.289 1.00 65.24  ? 14  SER C CB  1 
ATOM 981  O OG  . SER B 2 14  ? 167.970 242.823 111.390 1.00 65.24  ? 14  SER C OG  1 
ATOM 982  N N   . VAL B 2 15  ? 170.219 241.296 114.716 1.00 66.53  ? 15  VAL C N   1 
ATOM 983  C CA  . VAL B 2 15  ? 171.308 241.044 115.654 1.00 66.53  ? 15  VAL C CA  1 
ATOM 984  C C   . VAL B 2 15  ? 170.932 241.655 116.995 1.00 66.53  ? 15  VAL C C   1 
ATOM 985  O O   . VAL B 2 15  ? 170.360 242.746 117.058 1.00 66.53  ? 15  VAL C O   1 
ATOM 986  C CB  . VAL B 2 15  ? 172.650 241.605 115.122 1.00 66.53  ? 15  VAL C CB  1 
ATOM 987  C CG1 . VAL B 2 15  ? 172.533 243.093 114.824 1.00 66.53  ? 15  VAL C CG1 1 
ATOM 988  C CG2 . VAL B 2 15  ? 173.775 241.334 116.108 1.00 66.53  ? 15  VAL C CG2 1 
ATOM 989  N N   . GLY B 2 16  ? 171.246 240.934 118.070 1.00 67.73  ? 16  GLY C N   1 
ATOM 990  C CA  . GLY B 2 16  ? 171.013 241.441 119.409 1.00 67.73  ? 16  GLY C CA  1 
ATOM 991  C C   . GLY B 2 16  ? 169.563 241.686 119.751 1.00 67.73  ? 16  GLY C C   1 
ATOM 992  O O   . GLY B 2 16  ? 169.276 242.391 120.722 1.00 67.73  ? 16  GLY C O   1 
ATOM 993  N N   . ASP B 2 17  ? 168.637 241.124 118.982 1.00 71.44  ? 17  ASP C N   1 
ATOM 994  C CA  . ASP B 2 17  ? 167.218 241.327 119.216 1.00 71.44  ? 17  ASP C CA  1 
ATOM 995  C C   . ASP B 2 17  ? 166.695 240.296 120.213 1.00 71.44  ? 17  ASP C C   1 
ATOM 996  O O   . ASP B 2 17  ? 167.434 239.452 120.726 1.00 71.44  ? 17  ASP C O   1 
ATOM 997  C CB  . ASP B 2 17  ? 166.451 241.259 117.897 1.00 71.44  ? 17  ASP C CB  1 
ATOM 998  C CG  . ASP B 2 17  ? 167.026 242.180 116.842 1.00 71.44  ? 17  ASP C CG  1 
ATOM 999  O OD1 . ASP B 2 17  ? 167.560 243.247 117.211 1.00 71.44  ? 17  ASP C OD1 1 
ATOM 1000 O OD2 . ASP B 2 17  ? 166.946 241.838 115.644 1.00 71.44  ? 17  ASP C OD2 1 
ATOM 1001 N N   . ARG B 2 18  ? 165.398 240.368 120.498 1.00 75.67  ? 18  ARG C N   1 
ATOM 1002 C CA  . ARG B 2 18  ? 164.723 239.420 121.376 1.00 75.67  ? 18  ARG C CA  1 
ATOM 1003 C C   . ARG B 2 18  ? 163.852 238.518 120.511 1.00 75.67  ? 18  ARG C C   1 
ATOM 1004 O O   . ARG B 2 18  ? 162.857 238.972 119.935 1.00 75.67  ? 18  ARG C O   1 
ATOM 1005 C CB  . ARG B 2 18  ? 163.893 240.145 122.434 1.00 75.67  ? 18  ARG C CB  1 
ATOM 1006 C CG  . ARG B 2 18  ? 162.804 239.292 123.066 1.00 75.67  ? 18  ARG C CG  1 
ATOM 1007 C CD  . ARG B 2 18  ? 163.284 238.654 124.357 1.00 75.67  ? 18  ARG C CD  1 
ATOM 1008 N NE  . ARG B 2 18  ? 163.735 239.652 125.320 1.00 75.67  ? 18  ARG C NE  1 
ATOM 1009 C CZ  . ARG B 2 18  ? 164.140 239.375 126.551 1.00 75.67  ? 18  ARG C CZ  1 
ATOM 1010 N NH1 . ARG B 2 18  ? 164.164 238.133 127.008 1.00 75.67  ? 18  ARG C NH1 1 
ATOM 1011 N NH2 . ARG B 2 18  ? 164.532 240.368 127.344 1.00 75.67  ? 18  ARG C NH2 1 
ATOM 1012 N N   . VAL B 2 19  ? 164.232 237.247 120.412 1.00 68.66  ? 19  VAL C N   1 
ATOM 1013 C CA  . VAL B 2 19  ? 163.488 236.252 119.649 1.00 68.66  ? 19  VAL C CA  1 
ATOM 1014 C C   . VAL B 2 19  ? 162.967 235.224 120.641 1.00 68.66  ? 19  VAL C C   1 
ATOM 1015 O O   . VAL B 2 19  ? 163.753 234.521 121.289 1.00 68.66  ? 19  VAL C O   1 
ATOM 1016 C CB  . VAL B 2 19  ? 164.349 235.590 118.566 1.00 68.66  ? 19  VAL C CB  1 
ATOM 1017 N N   . THR B 2 20  ? 161.646 235.133 120.761 1.00 67.25  ? 20  THR C N   1 
ATOM 1018 C CA  . THR B 2 20  ? 160.996 234.234 121.704 1.00 67.25  ? 20  THR C CA  1 
ATOM 1019 C C   . THR B 2 20  ? 160.313 233.109 120.941 1.00 67.25  ? 20  THR C C   1 
ATOM 1020 O O   . THR B 2 20  ? 159.525 233.363 120.024 1.00 67.25  ? 20  THR C O   1 
ATOM 1021 C CB  . THR B 2 20  ? 159.977 234.985 122.565 1.00 67.25  ? 20  THR C CB  1 
ATOM 1022 O OG1 . THR B 2 20  ? 160.642 236.017 123.305 1.00 67.25  ? 20  THR C OG1 1 
ATOM 1023 C CG2 . THR B 2 20  ? 159.295 234.036 123.536 1.00 67.25  ? 20  THR C CG2 1 
ATOM 1024 N N   . ILE B 2 21  ? 160.618 231.870 121.320 1.00 61.28  ? 21  ILE C N   1 
ATOM 1025 C CA  . ILE B 2 21  ? 160.040 230.684 120.702 1.00 61.28  ? 21  ILE C CA  1 
ATOM 1026 C C   . ILE B 2 21  ? 159.329 229.889 121.787 1.00 61.28  ? 21  ILE C C   1 
ATOM 1027 O O   . ILE B 2 21  ? 159.930 229.557 122.815 1.00 61.28  ? 21  ILE C O   1 
ATOM 1028 C CB  . ILE B 2 21  ? 161.111 229.826 120.006 1.00 61.28  ? 21  ILE C CB  1 
ATOM 1029 C CG1 . ILE B 2 21  ? 161.760 230.608 118.864 1.00 61.28  ? 21  ILE C CG1 1 
ATOM 1030 C CG2 . ILE B 2 21  ? 160.497 228.547 119.470 1.00 61.28  ? 21  ILE C CG2 1 
ATOM 1031 C CD1 . ILE B 2 21  ? 162.991 229.943 118.298 1.00 61.28  ? 21  ILE C CD1 1 
ATOM 1032 N N   . THR B 2 22  ? 158.051 229.591 121.562 1.00 63.76  ? 22  THR C N   1 
ATOM 1033 C CA  . THR B 2 22  ? 157.207 228.927 122.545 1.00 63.76  ? 22  THR C CA  1 
ATOM 1034 C C   . THR B 2 22  ? 156.592 227.681 121.927 1.00 63.76  ? 22  THR C C   1 
ATOM 1035 O O   . THR B 2 22  ? 155.977 227.760 120.859 1.00 63.76  ? 22  THR C O   1 
ATOM 1036 C CB  . THR B 2 22  ? 156.094 229.857 123.033 1.00 63.76  ? 22  THR C CB  1 
ATOM 1037 O OG1 . THR B 2 22  ? 155.151 230.063 121.974 1.00 63.76  ? 22  THR C OG1 1 
ATOM 1038 C CG2 . THR B 2 22  ? 156.667 231.203 123.440 1.00 63.76  ? 22  THR C CG2 1 
ATOM 1039 N N   . CYS B 2 23  ? 156.743 226.540 122.599 1.00 59.74  ? 23  CYS C N   1 
ATOM 1040 C CA  . CYS B 2 23  ? 156.123 225.297 122.159 1.00 59.74  ? 23  CYS C CA  1 
ATOM 1041 C C   . CYS B 2 23  ? 155.227 224.746 123.259 1.00 59.74  ? 23  CYS C C   1 
ATOM 1042 O O   . CYS B 2 23  ? 155.592 224.761 124.439 1.00 59.74  ? 23  CYS C O   1 
ATOM 1043 C CB  . CYS B 2 23  ? 157.165 224.243 121.747 1.00 59.74  ? 23  CYS C CB  1 
ATOM 1044 S SG  . CYS B 2 23  ? 158.274 223.602 123.025 1.00 59.74  ? 23  CYS C SG  1 
ATOM 1045 N N   . ARG B 2 24  ? 154.052 224.265 122.859 1.00 63.36  ? 24  ARG C N   1 
ATOM 1046 C CA  . ARG B 2 24  ? 153.050 223.738 123.773 1.00 63.36  ? 24  ARG C CA  1 
ATOM 1047 C C   . ARG B 2 24  ? 152.880 222.243 123.550 1.00 63.36  ? 24  ARG C C   1 
ATOM 1048 O O   . ARG B 2 24  ? 152.811 221.779 122.407 1.00 63.36  ? 24  ARG C O   1 
ATOM 1049 C CB  . ARG B 2 24  ? 151.704 224.447 123.588 1.00 63.36  ? 24  ARG C CB  1 
ATOM 1050 N N   . ALA B 2 25  ? 152.809 221.496 124.647 1.00 67.57  ? 25  ALA C N   1 
ATOM 1051 C CA  . ALA B 2 25  ? 152.657 220.050 124.595 1.00 67.57  ? 25  ALA C CA  1 
ATOM 1052 C C   . ALA B 2 25  ? 151.186 219.673 124.487 1.00 67.57  ? 25  ALA C C   1 
ATOM 1053 O O   . ALA B 2 25  ? 150.330 220.268 125.149 1.00 67.57  ? 25  ALA C O   1 
ATOM 1054 C CB  . ALA B 2 25  ? 153.273 219.401 125.834 1.00 67.57  ? 25  ALA C CB  1 
ATOM 1055 N N   . SER B 2 26  ? 150.899 218.678 123.645 1.00 65.65  ? 26  SER C N   1 
ATOM 1056 C CA  . SER B 2 26  ? 149.521 218.225 123.481 1.00 65.65  ? 26  SER C CA  1 
ATOM 1057 C C   . SER B 2 26  ? 148.968 217.659 124.783 1.00 65.65  ? 26  SER C C   1 
ATOM 1058 O O   . SER B 2 26  ? 147.819 217.933 125.149 1.00 65.65  ? 26  SER C O   1 
ATOM 1059 C CB  . SER B 2 26  ? 149.440 217.184 122.365 1.00 65.65  ? 26  SER C CB  1 
ATOM 1060 O OG  . SER B 2 26  ? 149.560 217.794 121.092 1.00 65.65  ? 26  SER C OG  1 
ATOM 1061 N N   . GLN B 2 27  ? 149.767 216.870 125.493 1.00 67.41  ? 27  GLN C N   1 
ATOM 1062 C CA  . GLN B 2 27  ? 149.385 216.327 126.784 1.00 67.41  ? 27  GLN C CA  1 
ATOM 1063 C C   . GLN B 2 27  ? 150.140 217.056 127.893 1.00 67.41  ? 27  GLN C C   1 
ATOM 1064 O O   . GLN B 2 27  ? 150.898 217.998 127.654 1.00 67.41  ? 27  GLN C O   1 
ATOM 1065 C CB  . GLN B 2 27  ? 149.649 214.821 126.831 1.00 67.41  ? 27  GLN C CB  1 
ATOM 1066 N N   . GLY B 2 28  ? 149.925 216.611 129.127 1.00 74.17  ? 28  GLY C N   1 
ATOM 1067 C CA  . GLY B 2 28  ? 150.605 217.200 130.262 1.00 74.17  ? 28  GLY C CA  1 
ATOM 1068 C C   . GLY B 2 28  ? 151.961 216.574 130.510 1.00 74.17  ? 28  GLY C C   1 
ATOM 1069 O O   . GLY B 2 28  ? 152.061 215.359 130.706 1.00 74.17  ? 28  GLY C O   1 
ATOM 1070 N N   . ILE B 2 29  ? 153.013 217.391 130.502 1.00 73.41  ? 29  ILE C N   1 
ATOM 1071 C CA  . ILE B 2 29  ? 154.373 216.894 130.683 1.00 73.41  ? 29  ILE C CA  1 
ATOM 1072 C C   . ILE B 2 29  ? 155.042 217.601 131.854 1.00 73.41  ? 29  ILE C C   1 
ATOM 1073 O O   . ILE B 2 29  ? 156.274 217.682 131.919 1.00 73.41  ? 29  ILE C O   1 
ATOM 1074 C CB  . ILE B 2 29  ? 155.196 217.049 129.391 1.00 73.41  ? 29  ILE C CB  1 
ATOM 1075 C CG1 . ILE B 2 29  ? 155.324 218.519 128.999 1.00 73.41  ? 29  ILE C CG1 1 
ATOM 1076 C CG2 . ILE B 2 29  ? 154.575 216.253 128.260 1.00 73.41  ? 29  ILE C CG2 1 
ATOM 1077 C CD1 . ILE B 2 29  ? 156.308 218.750 127.877 1.00 73.41  ? 29  ILE C CD1 1 
ATOM 1078 N N   . SER B 2 30  ? 154.235 218.101 132.788 1.00 77.29  ? 30  SER C N   1 
ATOM 1079 C CA  . SER B 2 30  ? 154.713 218.754 134.017 1.00 77.29  ? 30  SER C CA  1 
ATOM 1080 C C   . SER B 2 30  ? 155.631 219.903 133.604 1.00 77.29  ? 30  SER C C   1 
ATOM 1081 O O   . SER B 2 30  ? 155.207 220.757 132.809 1.00 77.29  ? 30  SER C O   1 
ATOM 1082 C CB  . SER B 2 30  ? 155.335 217.707 134.933 1.00 77.29  ? 30  SER C CB  1 
ATOM 1083 N N   . SER B 2 31  ? 156.862 219.977 134.108 1.00 74.42  ? 31  SER C N   1 
ATOM 1084 C CA  . SER B 2 31  ? 157.815 221.004 133.709 1.00 74.42  ? 31  SER C CA  1 
ATOM 1085 C C   . SER B 2 31  ? 158.991 220.436 132.926 1.00 74.42  ? 31  SER C C   1 
ATOM 1086 O O   . SER B 2 31  ? 159.986 221.139 132.725 1.00 74.42  ? 31  SER C O   1 
ATOM 1087 C CB  . SER B 2 31  ? 158.323 221.765 134.934 1.00 74.42  ? 31  SER C CB  1 
ATOM 1088 O OG  . SER B 2 31  ? 159.441 222.571 134.602 1.00 74.42  ? 31  SER C OG  1 
ATOM 1089 N N   . TRP B 2 32  ? 158.906 219.183 132.491 1.00 70.07  ? 32  TRP C N   1 
ATOM 1090 C CA  . TRP B 2 32  ? 159.993 218.574 131.737 1.00 70.07  ? 32  TRP C CA  1 
ATOM 1091 C C   . TRP B 2 32  ? 160.106 219.197 130.352 1.00 70.07  ? 32  TRP C C   1 
ATOM 1092 O O   . TRP B 2 32  ? 159.101 219.438 129.678 1.00 70.07  ? 32  TRP C O   1 
ATOM 1093 C CB  . TRP B 2 32  ? 159.773 217.067 131.617 1.00 70.07  ? 32  TRP C CB  1 
ATOM 1094 C CG  . TRP B 2 32  ? 159.607 216.341 132.927 1.00 70.07  ? 32  TRP C CG  1 
ATOM 1095 C CD1 . TRP B 2 32  ? 158.725 215.335 133.191 1.00 70.07  ? 32  TRP C CD1 1 
ATOM 1096 C CD2 . TRP B 2 32  ? 160.368 216.531 134.132 1.00 70.07  ? 32  TRP C CD2 1 
ATOM 1097 N NE1 . TRP B 2 32  ? 158.869 214.904 134.486 1.00 70.07  ? 32  TRP C NE1 1 
ATOM 1098 C CE2 . TRP B 2 32  ? 159.872 215.619 135.085 1.00 70.07  ? 32  TRP C CE2 1 
ATOM 1099 C CE3 . TRP B 2 32  ? 161.412 217.387 134.501 1.00 70.07  ? 32  TRP C CE3 1 
ATOM 1100 C CZ2 . TRP B 2 32  ? 160.382 215.540 136.379 1.00 70.07  ? 32  TRP C CZ2 1 
ATOM 1101 C CZ3 . TRP B 2 32  ? 161.915 217.307 135.785 1.00 70.07  ? 32  TRP C CZ3 1 
ATOM 1102 C CH2 . TRP B 2 32  ? 161.400 216.390 136.708 1.00 70.07  ? 32  TRP C CH2 1 
ATOM 1103 N N   . LEU B 2 33  ? 161.342 219.450 129.928 1.00 56.04  ? 33  LEU C N   1 
ATOM 1104 C CA  . LEU B 2 33  ? 161.618 220.048 128.628 1.00 56.04  ? 33  LEU C CA  1 
ATOM 1105 C C   . LEU B 2 33  ? 163.111 219.978 128.349 1.00 56.04  ? 33  LEU C C   1 
ATOM 1106 O O   . LEU B 2 33  ? 163.925 219.894 129.273 1.00 56.04  ? 33  LEU C O   1 
ATOM 1107 C CB  . LEU B 2 33  ? 161.142 221.502 128.566 1.00 56.04  ? 33  LEU C CB  1 
ATOM 1108 C CG  . LEU B 2 33  ? 160.906 222.088 127.175 1.00 56.04  ? 33  LEU C CG  1 
ATOM 1109 C CD1 . LEU B 2 33  ? 159.798 221.358 126.434 1.00 56.04  ? 33  LEU C CD1 1 
ATOM 1110 C CD2 . LEU B 2 33  ? 160.588 223.560 127.305 1.00 56.04  ? 33  LEU C CD2 1 
ATOM 1111 N N   . ALA B 2 34  ? 163.455 220.018 127.062 1.00 46.77  ? 34  ALA C N   1 
ATOM 1112 C CA  . ALA B 2 34  ? 164.853 220.046 126.637 1.00 46.77  ? 34  ALA C CA  1 
ATOM 1113 C C   . ALA B 2 34  ? 164.919 220.815 125.320 1.00 46.77  ? 34  ALA C C   1 
ATOM 1114 O O   . ALA B 2 34  ? 164.675 220.243 124.255 1.00 46.77  ? 34  ALA C O   1 
ATOM 1115 C CB  . ALA B 2 34  ? 165.416 218.640 126.494 1.00 46.77  ? 34  ALA C CB  1 
ATOM 1116 N N   . TRP B 2 35  ? 165.242 222.102 125.401 1.00 42.13  ? 35  TRP C N   1 
ATOM 1117 C CA  . TRP B 2 35  ? 165.388 222.934 124.217 1.00 42.13  ? 35  TRP C CA  1 
ATOM 1118 C C   . TRP B 2 35  ? 166.747 222.682 123.579 1.00 42.13  ? 35  TRP C C   1 
ATOM 1119 O O   . TRP B 2 35  ? 167.760 222.593 124.276 1.00 42.13  ? 35  TRP C O   1 
ATOM 1120 C CB  . TRP B 2 35  ? 165.252 224.414 124.573 1.00 42.13  ? 35  TRP C CB  1 
ATOM 1121 C CG  . TRP B 2 35  ? 163.847 224.924 124.594 1.00 42.13  ? 35  TRP C CG  1 
ATOM 1122 C CD1 . TRP B 2 35  ? 163.117 225.254 125.695 1.00 42.13  ? 35  TRP C CD1 1 
ATOM 1123 C CD2 . TRP B 2 35  ? 163.004 225.174 123.464 1.00 42.13  ? 35  TRP C CD2 1 
ATOM 1124 N NE1 . TRP B 2 35  ? 161.872 225.694 125.322 1.00 42.13  ? 35  TRP C NE1 1 
ATOM 1125 C CE2 . TRP B 2 35  ? 161.778 225.652 123.956 1.00 42.13  ? 35  TRP C CE2 1 
ATOM 1126 C CE3 . TRP B 2 35  ? 163.168 225.042 122.084 1.00 42.13  ? 35  TRP C CE3 1 
ATOM 1127 C CZ2 . TRP B 2 35  ? 160.722 225.996 123.120 1.00 42.13  ? 35  TRP C CZ2 1 
ATOM 1128 C CZ3 . TRP B 2 35  ? 162.118 225.381 121.256 1.00 42.13  ? 35  TRP C CZ3 1 
ATOM 1129 C CH2 . TRP B 2 35  ? 160.911 225.852 121.776 1.00 42.13  ? 35  TRP C CH2 1 
ATOM 1130 N N   . TYR B 2 36  ? 166.768 222.577 122.255 1.00 33.88  ? 36  TYR C N   1 
ATOM 1131 C CA  . TYR B 2 36  ? 167.993 222.304 121.511 1.00 33.88  ? 36  TYR C CA  1 
ATOM 1132 C C   . TYR B 2 36  ? 168.278 223.434 120.526 1.00 33.88  ? 36  TYR C C   1 
ATOM 1133 O O   . TYR B 2 36  ? 167.582 224.449 120.487 1.00 33.88  ? 36  TYR C O   1 
ATOM 1134 C CB  . TYR B 2 36  ? 167.907 220.958 120.785 1.00 33.88  ? 36  TYR C CB  1 
ATOM 1135 C CG  . TYR B 2 36  ? 167.898 219.756 121.700 1.00 33.88  ? 36  TYR C CG  1 
ATOM 1136 C CD1 . TYR B 2 36  ? 168.262 219.871 123.030 1.00 33.88  ? 36  TYR C CD1 1 
ATOM 1137 C CD2 . TYR B 2 36  ? 167.533 218.507 121.233 1.00 33.88  ? 36  TYR C CD2 1 
ATOM 1138 C CE1 . TYR B 2 36  ? 168.257 218.786 123.868 1.00 33.88  ? 36  TYR C CE1 1 
ATOM 1139 C CE2 . TYR B 2 36  ? 167.527 217.414 122.067 1.00 33.88  ? 36  TYR C CE2 1 
ATOM 1140 C CZ  . TYR B 2 36  ? 167.889 217.561 123.383 1.00 33.88  ? 36  TYR C CZ  1 
ATOM 1141 O OH  . TYR B 2 36  ? 167.885 216.477 124.225 1.00 33.88  ? 36  TYR C OH  1 
ATOM 1142 N N   . GLN B 2 37  ? 169.323 223.239 119.723 1.00 40.54  ? 37  GLN C N   1 
ATOM 1143 C CA  . GLN B 2 37  ? 169.769 224.238 118.755 1.00 40.54  ? 37  GLN C CA  1 
ATOM 1144 C C   . GLN B 2 37  ? 170.425 223.521 117.588 1.00 40.54  ? 37  GLN C C   1 
ATOM 1145 O O   . GLN B 2 37  ? 171.501 222.939 117.746 1.00 40.54  ? 37  GLN C O   1 
ATOM 1146 C CB  . GLN B 2 37  ? 170.749 225.223 119.393 1.00 40.54  ? 37  GLN C CB  1 
ATOM 1147 C CG  . GLN B 2 37  ? 171.000 226.478 118.578 1.00 40.54  ? 37  GLN C CG  1 
ATOM 1148 C CD  . GLN B 2 37  ? 172.410 227.006 118.744 1.00 40.54  ? 37  GLN C CD  1 
ATOM 1149 O OE1 . GLN B 2 37  ? 173.069 226.743 119.749 1.00 40.54  ? 37  GLN C OE1 1 
ATOM 1150 N NE2 . GLN B 2 37  ? 172.880 227.758 117.757 1.00 40.54  ? 37  GLN C NE2 1 
ATOM 1151 N N   . GLN B 2 38  ? 169.790 223.572 116.421 1.00 42.86  ? 38  GLN C N   1 
ATOM 1152 C CA  . GLN B 2 38  ? 170.279 222.880 115.229 1.00 42.86  ? 38  GLN C CA  1 
ATOM 1153 C C   . GLN B 2 38  ? 171.078 223.871 114.390 1.00 42.86  ? 38  GLN C C   1 
ATOM 1154 O O   . GLN B 2 38  ? 170.537 224.572 113.534 1.00 42.86  ? 38  GLN C O   1 
ATOM 1155 C CB  . GLN B 2 38  ? 169.122 222.281 114.437 1.00 42.86  ? 38  GLN C CB  1 
ATOM 1156 C CG  . GLN B 2 38  ? 169.511 221.672 113.092 1.00 42.86  ? 38  GLN C CG  1 
ATOM 1157 C CD  . GLN B 2 38  ? 170.216 220.340 113.226 1.00 42.86  ? 38  GLN C CD  1 
ATOM 1158 O OE1 . GLN B 2 38  ? 169.798 219.479 113.997 1.00 42.86  ? 38  GLN C OE1 1 
ATOM 1159 N NE2 . GLN B 2 38  ? 171.292 220.161 112.470 1.00 42.86  ? 38  GLN C NE2 1 
ATOM 1160 N N   . THR B 2 39  ? 172.380 223.932 114.644 1.00 46.10  ? 39  THR C N   1 
ATOM 1161 C CA  . THR B 2 39  ? 173.262 224.678 113.766 1.00 46.10  ? 39  THR C CA  1 
ATOM 1162 C C   . THR B 2 39  ? 173.346 223.975 112.413 1.00 46.10  ? 39  THR C C   1 
ATOM 1163 O O   . THR B 2 39  ? 173.260 222.747 112.339 1.00 46.10  ? 39  THR C O   1 
ATOM 1164 C CB  . THR B 2 39  ? 174.653 224.802 114.379 1.00 46.10  ? 39  THR C CB  1 
ATOM 1165 O OG1 . THR B 2 39  ? 175.063 223.530 114.894 1.00 46.10  ? 39  THR C OG1 1 
ATOM 1166 C CG2 . THR B 2 39  ? 174.649 225.824 115.505 1.00 46.10  ? 39  THR C CG2 1 
ATOM 1167 N N   . PRO B 2 40  ? 173.496 224.730 111.326 1.00 49.71  ? 40  PRO C N   1 
ATOM 1168 C CA  . PRO B 2 40  ? 173.518 224.106 109.996 1.00 49.71  ? 40  PRO C CA  1 
ATOM 1169 C C   . PRO B 2 40  ? 174.679 223.131 109.855 1.00 49.71  ? 40  PRO C C   1 
ATOM 1170 O O   . PRO B 2 40  ? 175.831 223.463 110.141 1.00 49.71  ? 40  PRO C O   1 
ATOM 1171 C CB  . PRO B 2 40  ? 173.659 225.300 109.045 1.00 49.71  ? 40  PRO C CB  1 
ATOM 1172 C CG  . PRO B 2 40  ? 174.214 226.403 109.888 1.00 49.71  ? 40  PRO C CG  1 
ATOM 1173 C CD  . PRO B 2 40  ? 173.638 226.193 111.252 1.00 49.71  ? 40  PRO C CD  1 
ATOM 1174 N N   . GLY B 2 41  ? 174.362 221.921 109.405 1.00 49.36  ? 41  GLY C N   1 
ATOM 1175 C CA  . GLY B 2 41  ? 175.375 220.893 109.226 1.00 49.36  ? 41  GLY C CA  1 
ATOM 1176 C C   . GLY B 2 41  ? 176.063 220.468 110.505 1.00 49.36  ? 41  GLY C C   1 
ATOM 1177 O O   . GLY B 2 41  ? 177.283 220.265 110.513 1.00 49.36  ? 41  GLY C O   1 
ATOM 1178 N N   . LYS B 2 42  ? 175.307 220.326 111.591 1.00 43.18  ? 42  LYS C N   1 
ATOM 1179 C CA  . LYS B 2 42  ? 175.882 219.911 112.863 1.00 43.18  ? 42  LYS C CA  1 
ATOM 1180 C C   . LYS B 2 42  ? 174.781 219.336 113.741 1.00 43.18  ? 42  LYS C C   1 
ATOM 1181 O O   . LYS B 2 42  ? 173.590 219.538 113.490 1.00 43.18  ? 42  LYS C O   1 
ATOM 1182 C CB  . LYS B 2 42  ? 176.586 221.074 113.568 1.00 43.18  ? 42  LYS C CB  1 
ATOM 1183 N N   . ALA B 2 43  ? 175.200 218.609 114.773 1.00 38.90  ? 43  ALA C N   1 
ATOM 1184 C CA  . ALA B 2 43  ? 174.269 217.998 115.706 1.00 38.90  ? 43  ALA C CA  1 
ATOM 1185 C C   . ALA B 2 43  ? 173.677 219.046 116.643 1.00 38.90  ? 43  ALA C C   1 
ATOM 1186 O O   . ALA B 2 43  ? 174.344 220.023 116.994 1.00 38.90  ? 43  ALA C O   1 
ATOM 1187 C CB  . ALA B 2 43  ? 174.967 216.919 116.524 1.00 38.90  ? 43  ALA C CB  1 
ATOM 1188 N N   . PRO B 2 44  ? 172.420 218.873 117.050 1.00 39.03  ? 44  PRO C N   1 
ATOM 1189 C CA  . PRO B 2 44  ? 171.838 219.785 118.040 1.00 39.03  ? 44  PRO C CA  1 
ATOM 1190 C C   . PRO B 2 44  ? 172.600 219.734 119.353 1.00 39.03  ? 44  PRO C C   1 
ATOM 1191 O O   . PRO B 2 44  ? 173.038 218.671 119.798 1.00 39.03  ? 44  PRO C O   1 
ATOM 1192 C CB  . PRO B 2 44  ? 170.406 219.264 118.205 1.00 39.03  ? 44  PRO C CB  1 
ATOM 1193 C CG  . PRO B 2 44  ? 170.127 218.516 116.957 1.00 39.03  ? 44  PRO C CG  1 
ATOM 1194 C CD  . PRO B 2 44  ? 171.430 217.919 116.528 1.00 39.03  ? 44  PRO C CD  1 
ATOM 1195 N N   . LYS B 2 45  ? 172.749 220.895 119.978 1.00 37.81  ? 45  LYS C N   1 
ATOM 1196 C CA  . LYS B 2 45  ? 173.401 221.012 121.273 1.00 37.81  ? 45  LYS C CA  1 
ATOM 1197 C C   . LYS B 2 45  ? 172.376 221.451 122.308 1.00 37.81  ? 45  LYS C C   1 
ATOM 1198 O O   . LYS B 2 45  ? 171.673 222.447 122.106 1.00 37.81  ? 45  LYS C O   1 
ATOM 1199 C CB  . LYS B 2 45  ? 174.567 222.000 121.217 1.00 37.81  ? 45  LYS C CB  1 
ATOM 1200 C CG  . LYS B 2 45  ? 174.329 223.201 120.324 1.00 37.81  ? 45  LYS C CG  1 
ATOM 1201 C CD  . LYS B 2 45  ? 175.579 224.056 120.214 1.00 37.81  ? 45  LYS C CD  1 
ATOM 1202 C CE  . LYS B 2 45  ? 175.820 224.841 121.491 1.00 37.81  ? 45  LYS C CE  1 
ATOM 1203 N NZ  . LYS B 2 45  ? 174.777 225.879 121.705 1.00 37.81  ? 45  LYS C NZ  1 
ATOM 1204 N N   . LEU B 2 46  ? 172.291 220.704 123.404 1.00 39.01  ? 46  LEU C N   1 
ATOM 1205 C CA  . LEU B 2 46  ? 171.316 220.998 124.444 1.00 39.01  ? 46  LEU C CA  1 
ATOM 1206 C C   . LEU B 2 46  ? 171.523 222.405 124.986 1.00 39.01  ? 46  LEU C C   1 
ATOM 1207 O O   . LEU B 2 46  ? 172.651 222.817 125.268 1.00 39.01  ? 46  LEU C O   1 
ATOM 1208 C CB  . LEU B 2 46  ? 171.431 219.968 125.566 1.00 39.01  ? 46  LEU C CB  1 
ATOM 1209 C CG  . LEU B 2 46  ? 170.814 220.304 126.922 1.00 39.01  ? 46  LEU C CG  1 
ATOM 1210 C CD1 . LEU B 2 46  ? 169.315 220.485 126.810 1.00 39.01  ? 46  LEU C CD1 1 
ATOM 1211 C CD2 . LEU B 2 46  ? 171.144 219.219 127.927 1.00 39.01  ? 46  LEU C CD2 1 
ATOM 1212 N N   . LEU B 2 47  ? 170.426 223.147 125.123 1.00 42.50  ? 47  LEU C N   1 
ATOM 1213 C CA  . LEU B 2 47  ? 170.453 224.511 125.634 1.00 42.50  ? 47  LEU C CA  1 
ATOM 1214 C C   . LEU B 2 47  ? 169.817 224.633 127.009 1.00 42.50  ? 47  LEU C C   1 
ATOM 1215 O O   . LEU B 2 47  ? 170.441 225.152 127.938 1.00 42.50  ? 47  LEU C O   1 
ATOM 1216 C CB  . LEU B 2 47  ? 169.742 225.455 124.658 1.00 42.50  ? 47  LEU C CB  1 
ATOM 1217 C CG  . LEU B 2 47  ? 170.196 225.438 123.203 1.00 42.50  ? 47  LEU C CG  1 
ATOM 1218 C CD1 . LEU B 2 47  ? 169.431 226.487 122.429 1.00 42.50  ? 47  LEU C CD1 1 
ATOM 1219 C CD2 . LEU B 2 47  ? 171.687 225.684 123.111 1.00 42.50  ? 47  LEU C CD2 1 
ATOM 1220 N N   . ILE B 2 48  ? 168.579 224.176 127.160 1.00 48.21  ? 48  ILE C N   1 
ATOM 1221 C CA  . ILE B 2 48  ? 167.874 224.209 128.434 1.00 48.21  ? 48  ILE C CA  1 
ATOM 1222 C C   . ILE B 2 48  ? 167.317 222.819 128.693 1.00 48.21  ? 48  ILE C C   1 
ATOM 1223 O O   . ILE B 2 48  ? 166.717 222.213 127.799 1.00 48.21  ? 48  ILE C O   1 
ATOM 1224 C CB  . ILE B 2 48  ? 166.736 225.250 128.447 1.00 48.21  ? 48  ILE C CB  1 
ATOM 1225 C CG1 . ILE B 2 48  ? 167.274 226.670 128.259 1.00 48.21  ? 48  ILE C CG1 1 
ATOM 1226 C CG2 . ILE B 2 48  ? 165.944 225.161 129.742 1.00 48.21  ? 48  ILE C CG2 1 
ATOM 1227 C CD1 . ILE B 2 48  ? 167.382 227.108 126.814 1.00 48.21  ? 48  ILE C CD1 1 
ATOM 1228 N N   . TYR B 2 49  ? 167.521 222.310 129.904 1.00 56.05  ? 49  TYR C N   1 
ATOM 1229 C CA  . TYR B 2 49  ? 166.912 221.063 130.334 1.00 56.05  ? 49  TYR C CA  1 
ATOM 1230 C C   . TYR B 2 49  ? 166.053 221.325 131.562 1.00 56.05  ? 49  TYR C C   1 
ATOM 1231 O O   . TYR B 2 49  ? 166.387 222.164 132.404 1.00 56.05  ? 49  TYR C O   1 
ATOM 1232 C CB  . TYR B 2 49  ? 167.968 219.989 130.632 1.00 56.05  ? 49  TYR C CB  1 
ATOM 1233 C CG  . TYR B 2 49  ? 168.802 220.242 131.868 1.00 56.05  ? 49  TYR C CG  1 
ATOM 1234 C CD1 . TYR B 2 49  ? 169.851 221.148 131.849 1.00 56.05  ? 49  TYR C CD1 1 
ATOM 1235 C CD2 . TYR B 2 49  ? 168.546 219.562 133.050 1.00 56.05  ? 49  TYR C CD2 1 
ATOM 1236 C CE1 . TYR B 2 49  ? 170.617 221.376 132.975 1.00 56.05  ? 49  TYR C CE1 1 
ATOM 1237 C CE2 . TYR B 2 49  ? 169.304 219.783 134.180 1.00 56.05  ? 49  TYR C CE2 1 
ATOM 1238 C CZ  . TYR B 2 49  ? 170.340 220.690 134.138 1.00 56.05  ? 49  TYR C CZ  1 
ATOM 1239 O OH  . TYR B 2 49  ? 171.098 220.914 135.263 1.00 56.05  ? 49  TYR C OH  1 
ATOM 1240 N N   . ALA B 2 50  ? 164.929 220.611 131.642 1.00 62.48  ? 50  ALA C N   1 
ATOM 1241 C CA  . ALA B 2 50  ? 163.909 220.768 132.676 1.00 62.48  ? 50  ALA C CA  1 
ATOM 1242 C C   . ALA B 2 50  ? 163.228 222.131 132.632 1.00 62.48  ? 50  ALA C C   1 
ATOM 1243 O O   . ALA B 2 50  ? 162.553 222.511 133.597 1.00 62.48  ? 50  ALA C O   1 
ATOM 1244 C CB  . ALA B 2 50  ? 164.474 220.512 134.080 1.00 62.48  ? 50  ALA C CB  1 
ATOM 1245 N N   . ALA B 2 51  ? 163.419 222.888 131.548 1.00 64.81  ? 51  ALA C N   1 
ATOM 1246 C CA  . ALA B 2 51  ? 162.715 224.139 131.275 1.00 64.81  ? 51  ALA C CA  1 
ATOM 1247 C C   . ALA B 2 51  ? 163.088 225.259 132.241 1.00 64.81  ? 51  ALA C C   1 
ATOM 1248 O O   . ALA B 2 51  ? 162.625 226.392 132.082 1.00 64.81  ? 51  ALA C O   1 
ATOM 1249 C CB  . ALA B 2 51  ? 161.200 223.922 131.294 1.00 64.81  ? 51  ALA C CB  1 
ATOM 1250 N N   . SER B 2 52  ? 163.916 224.966 133.242 1.00 64.49  ? 52  SER C N   1 
ATOM 1251 C CA  . SER B 2 52  ? 164.344 225.997 134.178 1.00 64.49  ? 52  SER C CA  1 
ATOM 1252 C C   . SER B 2 52  ? 165.848 225.940 134.402 1.00 64.49  ? 52  SER C C   1 
ATOM 1253 O O   . SER B 2 52  ? 166.475 226.957 134.714 1.00 64.49  ? 52  SER C O   1 
ATOM 1254 C CB  . SER B 2 52  ? 163.603 225.853 135.509 1.00 64.49  ? 52  SER C CB  1 
ATOM 1255 O OG  . SER B 2 52  ? 162.229 226.166 135.364 1.00 64.49  ? 52  SER C OG  1 
ATOM 1256 N N   . SER B 2 53  ? 166.435 224.758 134.239 1.00 62.27  ? 53  SER C N   1 
ATOM 1257 C CA  . SER B 2 53  ? 167.859 224.556 134.477 1.00 62.27  ? 53  SER C CA  1 
ATOM 1258 C C   . SER B 2 53  ? 168.611 224.804 133.175 1.00 62.27  ? 53  SER C C   1 
ATOM 1259 O O   . SER B 2 53  ? 168.456 224.054 132.206 1.00 62.27  ? 53  SER C O   1 
ATOM 1260 C CB  . SER B 2 53  ? 168.122 223.150 135.009 1.00 62.27  ? 53  SER C CB  1 
ATOM 1261 N N   . LEU B 2 54  ? 169.423 225.855 133.154 1.00 63.81  ? 54  LEU C N   1 
ATOM 1262 C CA  . LEU B 2 54  ? 170.188 226.200 131.966 1.00 63.81  ? 54  LEU C CA  1 
ATOM 1263 C C   . LEU B 2 54  ? 171.392 225.273 131.856 1.00 63.81  ? 54  LEU C C   1 
ATOM 1264 O O   . LEU B 2 54  ? 172.127 225.078 132.829 1.00 63.81  ? 54  LEU C O   1 
ATOM 1265 C CB  . LEU B 2 54  ? 170.629 227.662 132.034 1.00 63.81  ? 54  LEU C CB  1 
ATOM 1266 C CG  . LEU B 2 54  ? 171.771 228.162 131.149 1.00 63.81  ? 54  LEU C CG  1 
ATOM 1267 C CD1 . LEU B 2 54  ? 171.514 227.827 129.691 1.00 63.81  ? 54  LEU C CD1 1 
ATOM 1268 C CD2 . LEU B 2 54  ? 171.965 229.658 131.331 1.00 63.81  ? 54  LEU C CD2 1 
ATOM 1269 N N   . GLN B 2 55  ? 171.587 224.697 130.673 1.00 64.87  ? 55  GLN C N   1 
ATOM 1270 C CA  . GLN B 2 55  ? 172.676 223.752 130.470 1.00 64.87  ? 55  GLN C CA  1 
ATOM 1271 C C   . GLN B 2 55  ? 174.025 224.447 130.595 1.00 64.87  ? 55  GLN C C   1 
ATOM 1272 O O   . GLN B 2 55  ? 174.205 225.581 130.143 1.00 64.87  ? 55  GLN C O   1 
ATOM 1273 C CB  . GLN B 2 55  ? 172.549 223.085 129.100 1.00 64.87  ? 55  GLN C CB  1 
ATOM 1274 C CG  . GLN B 2 55  ? 173.722 222.201 128.707 1.00 64.87  ? 55  GLN C CG  1 
ATOM 1275 C CD  . GLN B 2 55  ? 173.870 220.989 129.603 1.00 64.87  ? 55  GLN C CD  1 
ATOM 1276 O OE1 . GLN B 2 55  ? 172.930 220.587 130.288 1.00 64.87  ? 55  GLN C OE1 1 
ATOM 1277 N NE2 . GLN B 2 55  ? 175.057 220.395 129.600 1.00 64.87  ? 55  GLN C NE2 1 
ATOM 1278 N N   . SER B 2 56  ? 174.973 223.764 131.230 1.00 76.63  ? 56  SER C N   1 
ATOM 1279 C CA  . SER B 2 56  ? 176.324 224.291 131.349 1.00 76.63  ? 56  SER C CA  1 
ATOM 1280 C C   . SER B 2 56  ? 177.022 224.284 129.995 1.00 76.63  ? 56  SER C C   1 
ATOM 1281 O O   . SER B 2 56  ? 176.931 223.316 129.235 1.00 76.63  ? 56  SER C O   1 
ATOM 1282 C CB  . SER B 2 56  ? 177.124 223.469 132.356 1.00 76.63  ? 56  SER C CB  1 
ATOM 1283 O OG  . SER B 2 56  ? 176.974 222.082 132.114 1.00 76.63  ? 56  SER C OG  1 
ATOM 1284 N N   . GLY B 2 57  ? 177.728 225.372 129.696 1.00 75.46  ? 57  GLY C N   1 
ATOM 1285 C CA  . GLY B 2 57  ? 178.485 225.484 128.468 1.00 75.46  ? 57  GLY C CA  1 
ATOM 1286 C C   . GLY B 2 57  ? 177.838 226.303 127.373 1.00 75.46  ? 57  GLY C C   1 
ATOM 1287 O O   . GLY B 2 57  ? 178.383 226.358 126.264 1.00 75.46  ? 57  GLY C O   1 
ATOM 1288 N N   . VAL B 2 58  ? 176.701 226.936 127.641 1.00 69.10  ? 58  VAL C N   1 
ATOM 1289 C CA  . VAL B 2 58  ? 176.039 227.794 126.661 1.00 69.10  ? 58  VAL C CA  1 
ATOM 1290 C C   . VAL B 2 58  ? 175.733 229.130 127.330 1.00 69.10  ? 58  VAL C C   1 
ATOM 1291 O O   . VAL B 2 58  ? 175.630 229.188 128.564 1.00 69.10  ? 58  VAL C O   1 
ATOM 1292 C CB  . VAL B 2 58  ? 174.771 227.131 126.098 1.00 69.10  ? 58  VAL C CB  1 
ATOM 1293 C CG1 . VAL B 2 58  ? 175.134 225.928 125.239 1.00 69.10  ? 58  VAL C CG1 1 
ATOM 1294 C CG2 . VAL B 2 58  ? 173.842 226.723 127.217 1.00 69.10  ? 58  VAL C CG2 1 
ATOM 1295 N N   . PRO B 2 59  ? 175.594 230.219 126.574 1.00 68.85  ? 59  PRO C N   1 
ATOM 1296 C CA  . PRO B 2 59  ? 175.402 231.532 127.200 1.00 68.85  ? 59  PRO C CA  1 
ATOM 1297 C C   . PRO B 2 59  ? 174.119 231.598 128.013 1.00 68.85  ? 59  PRO C C   1 
ATOM 1298 O O   . PRO B 2 59  ? 173.192 230.805 127.839 1.00 68.85  ? 59  PRO C O   1 
ATOM 1299 C CB  . PRO B 2 59  ? 175.345 232.492 126.005 1.00 68.85  ? 59  PRO C CB  1 
ATOM 1300 C CG  . PRO B 2 59  ? 176.043 231.780 124.907 1.00 68.85  ? 59  PRO C CG  1 
ATOM 1301 C CD  . PRO B 2 59  ? 175.767 230.324 125.115 1.00 68.85  ? 59  PRO C CD  1 
ATOM 1302 N N   . SER B 2 60  ? 174.082 232.568 128.927 1.00 71.74  ? 60  SER C N   1 
ATOM 1303 C CA  . SER B 2 60  ? 172.883 232.819 129.716 1.00 71.74  ? 60  SER C CA  1 
ATOM 1304 C C   . SER B 2 60  ? 171.778 233.473 128.902 1.00 71.74  ? 60  SER C C   1 
ATOM 1305 O O   . SER B 2 60  ? 170.670 233.647 129.421 1.00 71.74  ? 60  SER C O   1 
ATOM 1306 C CB  . SER B 2 60  ? 173.218 233.692 130.925 1.00 71.74  ? 60  SER C CB  1 
ATOM 1307 O OG  . SER B 2 60  ? 172.153 233.691 131.860 1.00 71.74  ? 60  SER C OG  1 
ATOM 1308 N N   . ARG B 2 61  ? 172.059 233.854 127.655 1.00 68.70  ? 61  ARG C N   1 
ATOM 1309 C CA  . ARG B 2 61  ? 171.026 234.425 126.798 1.00 68.70  ? 61  ARG C CA  1 
ATOM 1310 C C   . ARG B 2 61  ? 169.912 233.420 126.538 1.00 68.70  ? 61  ARG C C   1 
ATOM 1311 O O   . ARG B 2 61  ? 168.729 233.782 126.525 1.00 68.70  ? 61  ARG C O   1 
ATOM 1312 C CB  . ARG B 2 61  ? 171.648 234.891 125.484 1.00 68.70  ? 61  ARG C CB  1 
ATOM 1313 C CG  . ARG B 2 61  ? 172.854 235.795 125.666 1.00 68.70  ? 61  ARG C CG  1 
ATOM 1314 C CD  . ARG B 2 61  ? 173.526 236.096 124.338 1.00 68.70  ? 61  ARG C CD  1 
ATOM 1315 N NE  . ARG B 2 61  ? 174.106 234.903 123.732 1.00 68.70  ? 61  ARG C NE  1 
ATOM 1316 C CZ  . ARG B 2 61  ? 173.657 234.333 122.622 1.00 68.70  ? 61  ARG C CZ  1 
ATOM 1317 N NH1 . ARG B 2 61  ? 172.613 234.817 121.969 1.00 68.70  ? 61  ARG C NH1 1 
ATOM 1318 N NH2 . ARG B 2 61  ? 174.273 233.252 122.155 1.00 68.70  ? 61  ARG C NH2 1 
ATOM 1319 N N   . PHE B 2 62  ? 170.269 232.155 126.327 1.00 56.78  ? 62  PHE C N   1 
ATOM 1320 C CA  . PHE B 2 62  ? 169.298 231.098 126.051 1.00 56.78  ? 62  PHE C CA  1 
ATOM 1321 C C   . PHE B 2 62  ? 168.622 230.710 127.358 1.00 56.78  ? 62  PHE C C   1 
ATOM 1322 O O   . PHE B 2 62  ? 169.120 229.883 128.122 1.00 56.78  ? 62  PHE C O   1 
ATOM 1323 C CB  . PHE B 2 62  ? 169.977 229.899 125.406 1.00 56.78  ? 62  PHE C CB  1 
ATOM 1324 C CG  . PHE B 2 62  ? 170.719 230.231 124.152 1.00 56.78  ? 62  PHE C CG  1 
ATOM 1325 C CD1 . PHE B 2 62  ? 170.114 230.964 123.151 1.00 56.78  ? 62  PHE C CD1 1 
ATOM 1326 C CD2 . PHE B 2 62  ? 172.019 229.797 123.967 1.00 56.78  ? 62  PHE C CD2 1 
ATOM 1327 C CE1 . PHE B 2 62  ? 170.795 231.273 121.995 1.00 56.78  ? 62  PHE C CE1 1 
ATOM 1328 C CE2 . PHE B 2 62  ? 172.705 230.098 122.809 1.00 56.78  ? 62  PHE C CE2 1 
ATOM 1329 C CZ  . PHE B 2 62  ? 172.091 230.836 121.821 1.00 56.78  ? 62  PHE C CZ  1 
ATOM 1330 N N   . SER B 2 63  ? 167.466 231.312 127.616 1.00 63.10  ? 63  SER C N   1 
ATOM 1331 C CA  . SER B 2 63  ? 166.712 231.055 128.832 1.00 63.10  ? 63  SER C CA  1 
ATOM 1332 C C   . SER B 2 63  ? 165.276 230.699 128.479 1.00 63.10  ? 63  SER C C   1 
ATOM 1333 O O   . SER B 2 63  ? 164.743 231.133 127.454 1.00 63.10  ? 63  SER C O   1 
ATOM 1334 C CB  . SER B 2 63  ? 166.733 232.265 129.774 1.00 63.10  ? 63  SER C CB  1 
ATOM 1335 O OG  . SER B 2 63  ? 168.030 232.472 130.306 1.00 63.10  ? 63  SER C OG  1 
ATOM 1336 N N   . GLY B 2 64  ? 164.658 229.890 129.338 1.00 68.59  ? 64  GLY C N   1 
ATOM 1337 C CA  . GLY B 2 64  ? 163.275 229.503 129.153 1.00 68.59  ? 64  GLY C CA  1 
ATOM 1338 C C   . GLY B 2 64  ? 162.630 229.201 130.487 1.00 68.59  ? 64  GLY C C   1 
ATOM 1339 O O   . GLY B 2 64  ? 163.302 229.068 131.512 1.00 68.59  ? 64  GLY C O   1 
ATOM 1340 N N   . SER B 2 65  ? 161.306 229.095 130.459 1.00 71.17  ? 65  SER C N   1 
ATOM 1341 C CA  . SER B 2 65  ? 160.530 228.806 131.658 1.00 71.17  ? 65  SER C CA  1 
ATOM 1342 C C   . SER B 2 65  ? 159.140 228.349 131.233 1.00 71.17  ? 65  SER C C   1 
ATOM 1343 O O   . SER B 2 65  ? 158.847 228.206 130.043 1.00 71.17  ? 65  SER C O   1 
ATOM 1344 C CB  . SER B 2 65  ? 160.462 230.026 132.582 1.00 71.17  ? 65  SER C CB  1 
ATOM 1345 O OG  . SER B 2 65  ? 160.123 229.645 133.904 1.00 71.17  ? 65  SER C OG  1 
ATOM 1346 N N   . GLY B 2 66  ? 158.285 228.120 132.222 1.00 75.85  ? 66  GLY C N   1 
ATOM 1347 C CA  . GLY B 2 66  ? 156.916 227.713 131.997 1.00 75.85  ? 66  GLY C CA  1 
ATOM 1348 C C   . GLY B 2 66  ? 156.528 226.546 132.876 1.00 75.85  ? 66  GLY C C   1 
ATOM 1349 O O   . GLY B 2 66  ? 157.320 226.025 133.659 1.00 75.85  ? 66  GLY C O   1 
ATOM 1350 N N   . SER B 2 67  ? 155.272 226.135 132.730 1.00 76.22  ? 67  SER C N   1 
ATOM 1351 C CA  . SER B 2 67  ? 154.731 225.014 133.485 1.00 76.22  ? 67  SER C CA  1 
ATOM 1352 C C   . SER B 2 67  ? 153.571 224.424 132.696 1.00 76.22  ? 67  SER C C   1 
ATOM 1353 O O   . SER B 2 67  ? 153.018 225.061 131.797 1.00 76.22  ? 67  SER C O   1 
ATOM 1354 C CB  . SER B 2 67  ? 154.285 225.443 134.886 1.00 76.22  ? 67  SER C CB  1 
ATOM 1355 N N   . GLY B 2 68  ? 153.211 223.193 133.046 1.00 78.14  ? 68  GLY C N   1 
ATOM 1356 C CA  . GLY B 2 68  ? 152.109 222.519 132.389 1.00 78.14  ? 68  GLY C CA  1 
ATOM 1357 C C   . GLY B 2 68  ? 152.371 222.217 130.929 1.00 78.14  ? 68  GLY C C   1 
ATOM 1358 O O   . GLY B 2 68  ? 153.209 221.371 130.606 1.00 78.14  ? 68  GLY C O   1 
ATOM 1359 N N   . THR B 2 69  ? 151.659 222.902 130.037 1.00 74.61  ? 69  THR C N   1 
ATOM 1360 C CA  . THR B 2 69  ? 151.770 222.676 128.601 1.00 74.61  ? 69  THR C CA  1 
ATOM 1361 C C   . THR B 2 69  ? 152.475 223.809 127.871 1.00 74.61  ? 69  THR C C   1 
ATOM 1362 O O   . THR B 2 69  ? 153.286 223.555 126.975 1.00 74.61  ? 69  THR C O   1 
ATOM 1363 C CB  . THR B 2 69  ? 150.377 222.460 127.992 1.00 74.61  ? 69  THR C CB  1 
ATOM 1364 N N   . ASP B 2 70  ? 152.186 225.060 128.225 1.00 73.46  ? 70  ASP C N   1 
ATOM 1365 C CA  . ASP B 2 70  ? 152.774 226.202 127.535 1.00 73.46  ? 70  ASP C CA  1 
ATOM 1366 C C   . ASP B 2 70  ? 154.194 226.435 128.038 1.00 73.46  ? 70  ASP C C   1 
ATOM 1367 O O   . ASP B 2 70  ? 154.394 226.813 129.198 1.00 73.46  ? 70  ASP C O   1 
ATOM 1368 C CB  . ASP B 2 70  ? 151.916 227.448 127.742 1.00 73.46  ? 70  ASP C CB  1 
ATOM 1369 N N   . PHE B 2 71  ? 155.174 226.228 127.161 1.00 69.63  ? 71  PHE C N   1 
ATOM 1370 C CA  . PHE B 2 71  ? 156.588 226.406 127.467 1.00 69.63  ? 71  PHE C CA  1 
ATOM 1371 C C   . PHE B 2 71  ? 157.199 227.419 126.512 1.00 69.63  ? 71  PHE C C   1 
ATOM 1372 O O   . PHE B 2 71  ? 156.828 227.479 125.336 1.00 69.63  ? 71  PHE C O   1 
ATOM 1373 C CB  . PHE B 2 71  ? 157.354 225.082 127.377 1.00 69.63  ? 71  PHE C CB  1 
ATOM 1374 C CG  . PHE B 2 71  ? 156.999 224.094 128.450 1.00 69.63  ? 71  PHE C CG  1 
ATOM 1375 C CD1 . PHE B 2 71  ? 156.304 224.489 129.576 1.00 69.63  ? 71  PHE C CD1 1 
ATOM 1376 C CD2 . PHE B 2 71  ? 157.358 222.766 128.328 1.00 69.63  ? 71  PHE C CD2 1 
ATOM 1377 C CE1 . PHE B 2 71  ? 155.983 223.582 130.558 1.00 69.63  ? 71  PHE C CE1 1 
ATOM 1378 C CE2 . PHE B 2 71  ? 157.041 221.857 129.308 1.00 69.63  ? 71  PHE C CE2 1 
ATOM 1379 C CZ  . PHE B 2 71  ? 156.351 222.264 130.423 1.00 69.63  ? 71  PHE C CZ  1 
ATOM 1380 N N   . THR B 2 72  ? 158.142 228.209 127.023 1.00 63.63  ? 72  THR C N   1 
ATOM 1381 C CA  . THR B 2 72  ? 158.700 229.336 126.293 1.00 63.63  ? 72  THR C CA  1 
ATOM 1382 C C   . THR B 2 72  ? 160.219 229.250 126.266 1.00 63.63  ? 72  THR C C   1 
ATOM 1383 O O   . THR B 2 72  ? 160.842 228.674 127.161 1.00 63.63  ? 72  THR C O   1 
ATOM 1384 C CB  . THR B 2 72  ? 158.286 230.674 126.926 1.00 63.63  ? 72  THR C CB  1 
ATOM 1385 O OG1 . THR B 2 72  ? 158.790 230.743 128.265 1.00 63.63  ? 72  THR C OG1 1 
ATOM 1386 C CG2 . THR B 2 72  ? 156.771 230.805 126.970 1.00 63.63  ? 72  THR C CG2 1 
ATOM 1387 N N   . LEU B 2 73  ? 160.806 229.832 125.223 1.00 58.25  ? 73  LEU C N   1 
ATOM 1388 C CA  . LEU B 2 73  ? 162.241 230.078 125.147 1.00 58.25  ? 73  LEU C CA  1 
ATOM 1389 C C   . LEU B 2 73  ? 162.450 231.544 124.806 1.00 58.25  ? 73  LEU C C   1 
ATOM 1390 O O   . LEU B 2 73  ? 161.845 232.052 123.857 1.00 58.25  ? 73  LEU C O   1 
ATOM 1391 C CB  . LEU B 2 73  ? 162.916 229.183 124.099 1.00 58.25  ? 73  LEU C CB  1 
ATOM 1392 C CG  . LEU B 2 73  ? 164.434 229.304 123.920 1.00 58.25  ? 73  LEU C CG  1 
ATOM 1393 C CD1 . LEU B 2 73  ? 165.047 227.964 123.569 1.00 58.25  ? 73  LEU C CD1 1 
ATOM 1394 C CD2 . LEU B 2 73  ? 164.771 230.315 122.838 1.00 58.25  ? 73  LEU C CD2 1 
ATOM 1395 N N   . THR B 2 74  ? 163.306 232.219 125.570 1.00 64.09  ? 74  THR C N   1 
ATOM 1396 C CA  . THR B 2 74  ? 163.593 233.632 125.361 1.00 64.09  ? 74  THR C CA  1 
ATOM 1397 C C   . THR B 2 74  ? 165.089 233.828 125.158 1.00 64.09  ? 74  THR C C   1 
ATOM 1398 O O   . THR B 2 74  ? 165.904 233.192 125.835 1.00 64.09  ? 74  THR C O   1 
ATOM 1399 C CB  . THR B 2 74  ? 163.082 234.483 126.533 1.00 64.09  ? 74  THR C CB  1 
ATOM 1400 O OG1 . THR B 2 74  ? 163.230 235.874 126.218 1.00 64.09  ? 74  THR C OG1 1 
ATOM 1401 C CG2 . THR B 2 74  ? 163.831 234.167 127.821 1.00 64.09  ? 74  THR C CG2 1 
ATOM 1402 N N   . ILE B 2 75  ? 165.442 234.680 124.200 1.00 66.11  ? 75  ILE C N   1 
ATOM 1403 C CA  . ILE B 2 75  ? 166.826 235.029 123.906 1.00 66.11  ? 75  ILE C CA  1 
ATOM 1404 C C   . ILE B 2 75  ? 167.012 236.505 124.230 1.00 66.11  ? 75  ILE C C   1 
ATOM 1405 O O   . ILE B 2 75  ? 166.366 237.366 123.620 1.00 66.11  ? 75  ILE C O   1 
ATOM 1406 C CB  . ILE B 2 75  ? 167.186 234.737 122.442 1.00 66.11  ? 75  ILE C CB  1 
ATOM 1407 C CG1 . ILE B 2 75  ? 167.079 233.240 122.156 1.00 66.11  ? 75  ILE C CG1 1 
ATOM 1408 C CG2 . ILE B 2 75  ? 168.580 235.250 122.126 1.00 66.11  ? 75  ILE C CG2 1 
ATOM 1409 C CD1 . ILE B 2 75  ? 167.720 232.822 120.853 1.00 66.11  ? 75  ILE C CD1 1 
ATOM 1410 N N   . SER B 2 76  ? 167.890 236.796 125.192 1.00 72.82  ? 76  SER C N   1 
ATOM 1411 C CA  . SER B 2 76  ? 168.113 238.182 125.593 1.00 72.82  ? 76  SER C CA  1 
ATOM 1412 C C   . SER B 2 76  ? 168.694 238.998 124.445 1.00 72.82  ? 76  SER C C   1 
ATOM 1413 O O   . SER B 2 76  ? 168.184 240.073 124.110 1.00 72.82  ? 76  SER C O   1 
ATOM 1414 C CB  . SER B 2 76  ? 169.034 238.230 126.812 1.00 72.82  ? 76  SER C CB  1 
ATOM 1415 O OG  . SER B 2 76  ? 170.325 237.740 126.494 1.00 72.82  ? 76  SER C OG  1 
ATOM 1416 N N   . SER B 2 77  ? 169.761 238.499 123.827 1.00 70.74  ? 77  SER C N   1 
ATOM 1417 C CA  . SER B 2 77  ? 170.396 239.174 122.704 1.00 70.74  ? 77  SER C CA  1 
ATOM 1418 C C   . SER B 2 77  ? 170.815 238.135 121.678 1.00 70.74  ? 77  SER C C   1 
ATOM 1419 O O   . SER B 2 77  ? 171.544 237.194 122.007 1.00 70.74  ? 77  SER C O   1 
ATOM 1420 C CB  . SER B 2 77  ? 171.609 239.993 123.161 1.00 70.74  ? 77  SER C CB  1 
ATOM 1421 O OG  . SER B 2 77  ? 172.596 239.162 123.747 1.00 70.74  ? 77  SER C OG  1 
ATOM 1422 N N   . LEU B 2 78  ? 170.355 238.307 120.440 1.00 68.12  ? 78  LEU C N   1 
ATOM 1423 C CA  . LEU B 2 78  ? 170.644 237.356 119.369 1.00 68.12  ? 78  LEU C CA  1 
ATOM 1424 C C   . LEU B 2 78  ? 172.034 237.647 118.825 1.00 68.12  ? 78  LEU C C   1 
ATOM 1425 O O   . LEU B 2 78  ? 172.221 238.496 117.954 1.00 68.12  ? 78  LEU C O   1 
ATOM 1426 C CB  . LEU B 2 78  ? 169.589 237.439 118.274 1.00 68.12  ? 78  LEU C CB  1 
ATOM 1427 C CG  . LEU B 2 78  ? 169.674 236.349 117.202 1.00 68.12  ? 78  LEU C CG  1 
ATOM 1428 C CD1 . LEU B 2 78  ? 169.144 235.033 117.740 1.00 68.12  ? 78  LEU C CD1 1 
ATOM 1429 C CD2 . LEU B 2 78  ? 168.924 236.761 115.949 1.00 68.12  ? 78  LEU C CD2 1 
ATOM 1430 N N   . GLN B 2 79  ? 173.025 236.933 119.347 1.00 70.40  ? 79  GLN C N   1 
ATOM 1431 C CA  . GLN B 2 79  ? 174.365 237.034 118.802 1.00 70.40  ? 79  GLN C CA  1 
ATOM 1432 C C   . GLN B 2 79  ? 174.394 236.442 117.394 1.00 70.40  ? 79  GLN C C   1 
ATOM 1433 O O   . GLN B 2 79  ? 173.584 235.574 117.062 1.00 70.40  ? 79  GLN C O   1 
ATOM 1434 C CB  . GLN B 2 79  ? 175.367 236.309 119.695 1.00 70.40  ? 79  GLN C CB  1 
ATOM 1435 N N   . PRO B 2 80  ? 175.307 236.914 116.541 1.00 69.67  ? 80  PRO C N   1 
ATOM 1436 C CA  . PRO B 2 80  ? 175.370 236.382 115.171 1.00 69.67  ? 80  PRO C CA  1 
ATOM 1437 C C   . PRO B 2 80  ? 175.559 234.876 115.104 1.00 69.67  ? 80  PRO C C   1 
ATOM 1438 O O   . PRO B 2 80  ? 175.187 234.266 114.094 1.00 69.67  ? 80  PRO C O   1 
ATOM 1439 C CB  . PRO B 2 80  ? 176.578 237.112 114.572 1.00 69.67  ? 80  PRO C CB  1 
ATOM 1440 C CG  . PRO B 2 80  ? 176.741 238.365 115.398 1.00 69.67  ? 80  PRO C CG  1 
ATOM 1441 C CD  . PRO B 2 80  ? 175.872 238.268 116.624 1.00 69.67  ? 80  PRO C CD  1 
ATOM 1442 N N   . GLU B 2 81  ? 176.127 234.258 116.142 1.00 71.89  ? 81  GLU C N   1 
ATOM 1443 C CA  . GLU B 2 81  ? 176.329 232.814 116.127 1.00 71.89  ? 81  GLU C CA  1 
ATOM 1444 C C   . GLU B 2 81  ? 175.012 232.052 116.224 1.00 71.89  ? 81  GLU C C   1 
ATOM 1445 O O   . GLU B 2 81  ? 174.896 230.952 115.673 1.00 71.89  ? 81  GLU C O   1 
ATOM 1446 C CB  . GLU B 2 81  ? 177.262 232.406 117.267 1.00 71.89  ? 81  GLU C CB  1 
ATOM 1447 C CG  . GLU B 2 81  ? 176.882 232.994 118.617 1.00 71.89  ? 81  GLU C CG  1 
ATOM 1448 C CD  . GLU B 2 81  ? 177.797 232.533 119.733 1.00 71.89  ? 81  GLU C CD  1 
ATOM 1449 O OE1 . GLU B 2 81  ? 178.449 231.480 119.570 1.00 71.89  ? 81  GLU C OE1 1 
ATOM 1450 O OE2 . GLU B 2 81  ? 177.866 233.223 120.771 1.00 71.89  ? 81  GLU C OE2 1 
ATOM 1451 N N   . ASP B 2 82  ? 174.018 232.608 116.910 1.00 62.17  ? 82  ASP C N   1 
ATOM 1452 C CA  . ASP B 2 82  ? 172.759 231.905 117.163 1.00 62.17  ? 82  ASP C CA  1 
ATOM 1453 C C   . ASP B 2 82  ? 171.775 232.057 116.006 1.00 62.17  ? 82  ASP C C   1 
ATOM 1454 O O   . ASP B 2 82  ? 170.630 232.467 116.188 1.00 62.17  ? 82  ASP C O   1 
ATOM 1455 C CB  . ASP B 2 82  ? 172.148 232.400 118.468 1.00 62.17  ? 82  ASP C CB  1 
ATOM 1456 N N   . PHE B 2 83  ? 172.223 231.727 114.800 1.00 64.37  ? 83  PHE C N   1 
ATOM 1457 C CA  . PHE B 2 83  ? 171.355 231.690 113.622 1.00 64.37  ? 83  PHE C CA  1 
ATOM 1458 C C   . PHE B 2 83  ? 170.973 230.248 113.289 1.00 64.37  ? 83  PHE C C   1 
ATOM 1459 O O   . PHE B 2 83  ? 171.317 229.714 112.235 1.00 64.37  ? 83  PHE C O   1 
ATOM 1460 C CB  . PHE B 2 83  ? 172.046 232.363 112.440 1.00 64.37  ? 83  PHE C CB  1 
ATOM 1461 C CG  . PHE B 2 83  ? 171.962 233.861 112.458 1.00 64.37  ? 83  PHE C CG  1 
ATOM 1462 C CD1 . PHE B 2 83  ? 170.944 234.504 113.141 1.00 64.37  ? 83  PHE C CD1 1 
ATOM 1463 C CD2 . PHE B 2 83  ? 172.903 234.627 111.792 1.00 64.37  ? 83  PHE C CD2 1 
ATOM 1464 C CE1 . PHE B 2 83  ? 170.867 235.883 113.157 1.00 64.37  ? 83  PHE C CE1 1 
ATOM 1465 C CE2 . PHE B 2 83  ? 172.831 236.005 111.805 1.00 64.37  ? 83  PHE C CE2 1 
ATOM 1466 C CZ  . PHE B 2 83  ? 171.812 236.634 112.488 1.00 64.37  ? 83  PHE C CZ  1 
ATOM 1467 N N   . ALA B 2 84  ? 170.242 229.614 114.202 1.00 51.10  ? 84  ALA C N   1 
ATOM 1468 C CA  . ALA B 2 84  ? 169.995 228.183 114.117 1.00 51.10  ? 84  ALA C CA  1 
ATOM 1469 C C   . ALA B 2 84  ? 168.540 227.860 114.427 1.00 51.10  ? 84  ALA C C   1 
ATOM 1470 O O   . ALA B 2 84  ? 167.790 228.689 114.944 1.00 51.10  ? 84  ALA C O   1 
ATOM 1471 C CB  . ALA B 2 84  ? 170.912 227.408 115.069 1.00 51.10  ? 84  ALA C CB  1 
ATOM 1472 N N   . THR B 2 85  ? 168.153 226.632 114.087 1.00 45.26  ? 85  THR C N   1 
ATOM 1473 C CA  . THR B 2 85  ? 166.820 226.131 114.388 1.00 45.26  ? 85  THR C CA  1 
ATOM 1474 C C   . THR B 2 85  ? 166.776 225.599 115.814 1.00 45.26  ? 85  THR C C   1 
ATOM 1475 O O   . THR B 2 85  ? 167.733 224.980 116.287 1.00 45.26  ? 85  THR C O   1 
ATOM 1476 C CB  . THR B 2 85  ? 166.434 225.026 113.404 1.00 45.26  ? 85  THR C CB  1 
ATOM 1477 O OG1 . THR B 2 85  ? 166.746 225.443 112.069 1.00 45.26  ? 85  THR C OG1 1 
ATOM 1478 C CG2 . THR B 2 85  ? 164.949 224.732 113.489 1.00 45.26  ? 85  THR C CG2 1 
ATOM 1479 N N   . TYR B 2 86  ? 165.661 225.840 116.501 1.00 42.91  ? 86  TYR C N   1 
ATOM 1480 C CA  . TYR B 2 86  ? 165.515 225.489 117.910 1.00 42.91  ? 86  TYR C CA  1 
ATOM 1481 C C   . TYR B 2 86  ? 164.425 224.438 118.059 1.00 42.91  ? 86  TYR C C   1 
ATOM 1482 O O   . TYR B 2 86  ? 163.306 224.629 117.573 1.00 42.91  ? 86  TYR C O   1 
ATOM 1483 C CB  . TYR B 2 86  ? 165.192 226.724 118.750 1.00 42.91  ? 86  TYR C CB  1 
ATOM 1484 C CG  . TYR B 2 86  ? 166.367 227.657 118.946 1.00 42.91  ? 86  TYR C CG  1 
ATOM 1485 C CD1 . TYR B 2 86  ? 166.813 227.991 120.216 1.00 42.91  ? 86  TYR C CD1 1 
ATOM 1486 C CD2 . TYR B 2 86  ? 167.031 228.204 117.857 1.00 42.91  ? 86  TYR C CD2 1 
ATOM 1487 C CE1 . TYR B 2 86  ? 167.885 228.844 120.392 1.00 42.91  ? 86  TYR C CE1 1 
ATOM 1488 C CE2 . TYR B 2 86  ? 168.101 229.051 118.024 1.00 42.91  ? 86  TYR C CE2 1 
ATOM 1489 C CZ  . TYR B 2 86  ? 168.524 229.368 119.290 1.00 42.91  ? 86  TYR C CZ  1 
ATOM 1490 O OH  . TYR B 2 86  ? 169.592 230.217 119.447 1.00 42.91  ? 86  TYR C OH  1 
ATOM 1491 N N   . TYR B 2 87  ? 164.752 223.339 118.733 1.00 38.58  ? 87  TYR C N   1 
ATOM 1492 C CA  . TYR B 2 87  ? 163.832 222.238 118.972 1.00 38.58  ? 87  TYR C CA  1 
ATOM 1493 C C   . TYR B 2 87  ? 163.581 222.076 120.464 1.00 38.58  ? 87  TYR C C   1 
ATOM 1494 O O   . TYR B 2 87  ? 164.458 222.344 121.288 1.00 38.58  ? 87  TYR C O   1 
ATOM 1495 C CB  . TYR B 2 87  ? 164.383 220.921 118.423 1.00 38.58  ? 87  TYR C CB  1 
ATOM 1496 C CG  . TYR B 2 87  ? 164.757 220.960 116.970 1.00 38.58  ? 87  TYR C CG  1 
ATOM 1497 C CD1 . TYR B 2 87  ? 163.895 221.491 116.029 1.00 38.58  ? 87  TYR C CD1 1 
ATOM 1498 C CD2 . TYR B 2 87  ? 165.974 220.470 116.538 1.00 38.58  ? 87  TYR C CD2 1 
ATOM 1499 C CE1 . TYR B 2 87  ? 164.234 221.528 114.697 1.00 38.58  ? 87  TYR C CE1 1 
ATOM 1500 C CE2 . TYR B 2 87  ? 166.323 220.513 115.211 1.00 38.58  ? 87  TYR C CE2 1 
ATOM 1501 C CZ  . TYR B 2 87  ? 165.448 221.037 114.293 1.00 38.58  ? 87  TYR C CZ  1 
ATOM 1502 O OH  . TYR B 2 87  ? 165.790 221.076 112.962 1.00 38.58  ? 87  TYR C OH  1 
ATOM 1503 N N   . CYS B 2 88  ? 162.381 221.616 120.802 1.00 45.32  ? 88  CYS C N   1 
ATOM 1504 C CA  . CYS B 2 88  ? 162.037 221.264 122.172 1.00 45.32  ? 88  CYS C CA  1 
ATOM 1505 C C   . CYS B 2 88  ? 161.496 219.845 122.179 1.00 45.32  ? 88  CYS C C   1 
ATOM 1506 O O   . CYS B 2 88  ? 160.756 219.459 121.270 1.00 45.32  ? 88  CYS C O   1 
ATOM 1507 C CB  . CYS B 2 88  ? 161.006 222.237 122.768 1.00 45.32  ? 88  CYS C CB  1 
ATOM 1508 S SG  . CYS B 2 88  ? 159.339 222.166 122.048 1.00 45.32  ? 88  CYS C SG  1 
ATOM 1509 N N   . GLN B 2 89  ? 161.876 219.066 123.186 1.00 47.61  ? 89  GLN C N   1 
ATOM 1510 C CA  . GLN B 2 89  ? 161.306 217.744 123.387 1.00 47.61  ? 89  GLN C CA  1 
ATOM 1511 C C   . GLN B 2 89  ? 160.717 217.652 124.787 1.00 47.61  ? 89  GLN C C   1 
ATOM 1512 O O   . GLN B 2 89  ? 160.911 218.528 125.631 1.00 47.61  ? 89  GLN C O   1 
ATOM 1513 C CB  . GLN B 2 89  ? 162.342 216.629 123.202 1.00 47.61  ? 89  GLN C CB  1 
ATOM 1514 C CG  . GLN B 2 89  ? 163.449 216.642 124.233 1.00 47.61  ? 89  GLN C CG  1 
ATOM 1515 C CD  . GLN B 2 89  ? 164.482 215.565 123.994 1.00 47.61  ? 89  GLN C CD  1 
ATOM 1516 O OE1 . GLN B 2 89  ? 165.475 215.471 124.711 1.00 47.61  ? 89  GLN C OE1 1 
ATOM 1517 N NE2 . GLN B 2 89  ? 164.260 214.752 122.969 1.00 47.61  ? 89  GLN C NE2 1 
ATOM 1518 N N   . GLN B 2 90  ? 159.997 216.563 125.024 1.00 55.37  ? 90  GLN C N   1 
ATOM 1519 C CA  . GLN B 2 90  ? 159.414 216.273 126.321 1.00 55.37  ? 90  GLN C CA  1 
ATOM 1520 C C   . GLN B 2 90  ? 160.297 215.286 127.078 1.00 55.37  ? 90  GLN C C   1 
ATOM 1521 O O   . GLN B 2 90  ? 161.209 214.671 126.523 1.00 55.37  ? 90  GLN C O   1 
ATOM 1522 C CB  . GLN B 2 90  ? 157.998 215.724 126.151 1.00 55.37  ? 90  GLN C CB  1 
ATOM 1523 C CG  . GLN B 2 90  ? 157.952 214.223 125.925 1.00 55.37  ? 90  GLN C CG  1 
ATOM 1524 C CD  . GLN B 2 90  ? 157.762 213.858 124.468 1.00 55.37  ? 90  GLN C CD  1 
ATOM 1525 O OE1 . GLN B 2 90  ? 158.291 214.521 123.575 1.00 55.37  ? 90  GLN C OE1 1 
ATOM 1526 N NE2 . GLN B 2 90  ? 157.006 212.798 124.220 1.00 55.37  ? 90  GLN C NE2 1 
ATOM 1527 N N   . ALA B 2 91  ? 160.027 215.143 128.372 1.00 63.11  ? 91  ALA C N   1 
ATOM 1528 C CA  . ALA B 2 91  ? 160.665 214.120 129.190 1.00 63.11  ? 91  ALA C CA  1 
ATOM 1529 C C   . ALA B 2 91  ? 159.637 213.462 130.098 1.00 63.11  ? 91  ALA C C   1 
ATOM 1530 O O   . ALA B 2 91  ? 159.934 213.080 131.235 1.00 63.11  ? 91  ALA C O   1 
ATOM 1531 C CB  . ALA B 2 91  ? 161.825 214.696 130.001 1.00 63.11  ? 91  ALA C CB  1 
ATOM 1532 N N   . ASN B 2 92  ? 158.407 213.325 129.604 1.00 67.39  ? 92  ASN C N   1 
ATOM 1533 C CA  . ASN B 2 92  ? 157.346 212.661 130.349 1.00 67.39  ? 92  ASN C CA  1 
ATOM 1534 C C   . ASN B 2 92  ? 156.997 211.337 129.686 1.00 67.39  ? 92  ASN C C   1 
ATOM 1535 O O   . ASN B 2 92  ? 157.136 210.272 130.295 1.00 67.39  ? 92  ASN C O   1 
ATOM 1536 C CB  . ASN B 2 92  ? 156.107 213.554 130.435 1.00 67.39  ? 92  ASN C CB  1 
ATOM 1537 C CG  . ASN B 2 92  ? 155.037 212.984 131.348 1.00 67.39  ? 92  ASN C CG  1 
ATOM 1538 O OD1 . ASN B 2 92  ? 155.203 211.914 131.933 1.00 67.39  ? 92  ASN C OD1 1 
ATOM 1539 N ND2 . ASN B 2 92  ? 153.922 213.694 131.463 1.00 67.39  ? 92  ASN C ND2 1 
ATOM 1540 N N   . SER B 2 93  ? 156.546 211.397 128.436 1.00 58.30  ? 93  SER C N   1 
ATOM 1541 C CA  . SER B 2 93  ? 156.274 210.184 127.687 1.00 58.30  ? 93  SER C CA  1 
ATOM 1542 C C   . SER B 2 93  ? 157.569 209.639 127.097 1.00 58.30  ? 93  SER C C   1 
ATOM 1543 O O   . SER B 2 93  ? 158.529 210.371 126.842 1.00 58.30  ? 93  SER C O   1 
ATOM 1544 C CB  . SER B 2 93  ? 155.252 210.450 126.583 1.00 58.30  ? 93  SER C CB  1 
ATOM 1545 N N   . PHE B 2 94  ? 157.593 208.333 126.882 1.00 51.34  ? 94  PHE C N   1 
ATOM 1546 C CA  . PHE B 2 94  ? 158.808 207.705 126.387 1.00 51.34  ? 94  PHE C CA  1 
ATOM 1547 C C   . PHE B 2 94  ? 159.017 207.902 124.886 1.00 51.34  ? 94  PHE C C   1 
ATOM 1548 O O   . PHE B 2 94  ? 160.151 208.164 124.469 1.00 51.34  ? 94  PHE C O   1 
ATOM 1549 C CB  . PHE B 2 94  ? 158.827 206.217 126.723 1.00 51.34  ? 94  PHE C CB  1 
ATOM 1550 C CG  . PHE B 2 94  ? 160.133 205.565 126.416 1.00 51.34  ? 94  PHE C CG  1 
ATOM 1551 C CD1 . PHE B 2 94  ? 161.302 206.043 126.977 1.00 51.34  ? 94  PHE C CD1 1 
ATOM 1552 C CD2 . PHE B 2 94  ? 160.200 204.494 125.550 1.00 51.34  ? 94  PHE C CD2 1 
ATOM 1553 C CE1 . PHE B 2 94  ? 162.508 205.457 126.693 1.00 51.34  ? 94  PHE C CE1 1 
ATOM 1554 C CE2 . PHE B 2 94  ? 161.405 203.903 125.263 1.00 51.34  ? 94  PHE C CE2 1 
ATOM 1555 C CZ  . PHE B 2 94  ? 162.561 204.384 125.836 1.00 51.34  ? 94  PHE C CZ  1 
ATOM 1556 N N   . PRO B 2 95  ? 157.980 207.789 124.030 1.00 48.41  ? 95  PRO C N   1 
ATOM 1557 C CA  . PRO B 2 95  ? 158.211 208.050 122.602 1.00 48.41  ? 95  PRO C CA  1 
ATOM 1558 C C   . PRO B 2 95  ? 158.530 209.513 122.353 1.00 48.41  ? 95  PRO C C   1 
ATOM 1559 O O   . PRO B 2 95  ? 157.661 210.284 121.938 1.00 48.41  ? 95  PRO C O   1 
ATOM 1560 C CB  . PRO B 2 95  ? 156.889 207.637 121.944 1.00 48.41  ? 95  PRO C CB  1 
ATOM 1561 C CG  . PRO B 2 95  ? 155.887 207.708 123.031 1.00 48.41  ? 95  PRO C CG  1 
ATOM 1562 C CD  . PRO B 2 95  ? 156.620 207.268 124.256 1.00 48.41  ? 95  PRO C CD  1 
ATOM 1563 N N   . PHE B 2 96  ? 159.781 209.891 122.623 1.00 46.33  ? 96  PHE C N   1 
ATOM 1564 C CA  . PHE B 2 96  ? 160.201 211.287 122.593 1.00 46.33  ? 96  PHE C CA  1 
ATOM 1565 C C   . PHE B 2 96  ? 159.871 211.934 121.256 1.00 46.33  ? 96  PHE C C   1 
ATOM 1566 O O   . PHE B 2 96  ? 160.158 211.379 120.193 1.00 46.33  ? 96  PHE C O   1 
ATOM 1567 C CB  . PHE B 2 96  ? 161.703 211.379 122.856 1.00 46.33  ? 96  PHE C CB  1 
ATOM 1568 C CG  . PHE B 2 96  ? 162.091 211.089 124.274 1.00 46.33  ? 96  PHE C CG  1 
ATOM 1569 C CD1 . PHE B 2 96  ? 161.539 211.804 125.316 1.00 46.33  ? 96  PHE C CD1 1 
ATOM 1570 C CD2 . PHE B 2 96  ? 163.018 210.104 124.562 1.00 46.33  ? 96  PHE C CD2 1 
ATOM 1571 C CE1 . PHE B 2 96  ? 161.900 211.541 126.619 1.00 46.33  ? 96  PHE C CE1 1 
ATOM 1572 C CE2 . PHE B 2 96  ? 163.382 209.837 125.863 1.00 46.33  ? 96  PHE C CE2 1 
ATOM 1573 C CZ  . PHE B 2 96  ? 162.823 210.556 126.893 1.00 46.33  ? 96  PHE C CZ  1 
ATOM 1574 N N   . THR B 2 97  ? 159.268 213.117 121.318 1.00 51.49  ? 97  THR C N   1 
ATOM 1575 C CA  . THR B 2 97  ? 158.840 213.850 120.136 1.00 51.49  ? 97  THR C CA  1 
ATOM 1576 C C   . THR B 2 97  ? 159.559 215.188 120.076 1.00 51.49  ? 97  THR C C   1 
ATOM 1577 O O   . THR B 2 97  ? 159.601 215.922 121.069 1.00 51.49  ? 97  THR C O   1 
ATOM 1578 C CB  . THR B 2 97  ? 157.327 214.072 120.142 1.00 51.49  ? 97  THR C CB  1 
ATOM 1579 O OG1 . THR B 2 97  ? 156.965 214.851 121.289 1.00 51.49  ? 97  THR C OG1 1 
ATOM 1580 C CG2 . THR B 2 97  ? 156.590 212.745 120.176 1.00 51.49  ? 97  THR C CG2 1 
ATOM 1581 N N   . PHE B 2 98  ? 160.114 215.501 118.911 1.00 43.12  ? 98  PHE C N   1 
ATOM 1582 C CA  . PHE B 2 98  ? 160.765 216.777 118.662 1.00 43.12  ? 98  PHE C CA  1 
ATOM 1583 C C   . PHE B 2 98  ? 159.824 217.682 117.882 1.00 43.12  ? 98  PHE C C   1 
ATOM 1584 O O   . PHE B 2 98  ? 159.095 217.222 116.999 1.00 43.12  ? 98  PHE C O   1 
ATOM 1585 C CB  . PHE B 2 98  ? 162.065 216.585 117.881 1.00 43.12  ? 98  PHE C CB  1 
ATOM 1586 C CG  . PHE B 2 98  ? 163.186 216.021 118.700 1.00 43.12  ? 98  PHE C CG  1 
ATOM 1587 C CD1 . PHE B 2 98  ? 163.931 216.834 119.532 1.00 43.12  ? 98  PHE C CD1 1 
ATOM 1588 C CD2 . PHE B 2 98  ? 163.499 214.677 118.632 1.00 43.12  ? 98  PHE C CD2 1 
ATOM 1589 C CE1 . PHE B 2 98  ? 164.960 216.316 120.280 1.00 43.12  ? 98  PHE C CE1 1 
ATOM 1590 C CE2 . PHE B 2 98  ? 164.530 214.156 119.380 1.00 43.12  ? 98  PHE C CE2 1 
ATOM 1591 C CZ  . PHE B 2 98  ? 165.264 214.977 120.203 1.00 43.12  ? 98  PHE C CZ  1 
ATOM 1592 N N   . GLY B 2 99  ? 159.844 218.969 118.211 1.00 46.47  ? 99  GLY C N   1 
ATOM 1593 C CA  . GLY B 2 99  ? 159.001 219.931 117.545 1.00 46.47  ? 99  GLY C CA  1 
ATOM 1594 C C   . GLY B 2 99  ? 159.373 220.100 116.087 1.00 46.47  ? 99  GLY C C   1 
ATOM 1595 O O   . GLY B 2 99  ? 160.465 219.719 115.654 1.00 46.47  ? 99  GLY C O   1 
ATOM 1596 N N   . PRO B 2 100 ? 158.461 220.669 115.295 1.00 50.09  ? 100 PRO C N   1 
ATOM 1597 C CA  . PRO B 2 100 ? 158.744 220.838 113.860 1.00 50.09  ? 100 PRO C CA  1 
ATOM 1598 C C   . PRO B 2 100 ? 159.971 221.689 113.581 1.00 50.09  ? 100 PRO C C   1 
ATOM 1599 O O   . PRO B 2 100 ? 160.672 221.443 112.592 1.00 50.09  ? 100 PRO C O   1 
ATOM 1600 C CB  . PRO B 2 100 ? 157.463 221.493 113.323 1.00 50.09  ? 100 PRO C CB  1 
ATOM 1601 C CG  . PRO B 2 100 ? 156.800 222.091 114.523 1.00 50.09  ? 100 PRO C CG  1 
ATOM 1602 C CD  . PRO B 2 100 ? 157.141 221.199 115.671 1.00 50.09  ? 100 PRO C CD  1 
ATOM 1603 N N   . GLY B 2 101 ? 160.251 222.683 114.419 1.00 47.62  ? 101 GLY C N   1 
ATOM 1604 C CA  . GLY B 2 101 ? 161.464 223.464 114.282 1.00 47.62  ? 101 GLY C CA  1 
ATOM 1605 C C   . GLY B 2 101 ? 161.249 224.922 113.939 1.00 47.62  ? 101 GLY C C   1 
ATOM 1606 O O   . GLY B 2 101 ? 160.717 225.246 112.874 1.00 47.62  ? 101 GLY C O   1 
ATOM 1607 N N   . THR B 2 102 ? 161.667 225.811 114.836 1.00 54.57  ? 102 THR C N   1 
ATOM 1608 C CA  . THR B 2 102 ? 161.634 227.251 114.607 1.00 54.57  ? 102 THR C CA  1 
ATOM 1609 C C   . THR B 2 102 ? 163.049 227.702 114.276 1.00 54.57  ? 102 THR C C   1 
ATOM 1610 O O   . THR B 2 102 ? 163.953 227.583 115.109 1.00 54.57  ? 102 THR C O   1 
ATOM 1611 C CB  . THR B 2 102 ? 161.100 227.994 115.828 1.00 54.57  ? 102 THR C CB  1 
ATOM 1612 O OG1 . THR B 2 102 ? 159.944 227.316 116.332 1.00 54.57  ? 102 THR C OG1 1 
ATOM 1613 C CG2 . THR B 2 102 ? 160.722 229.416 115.455 1.00 54.57  ? 102 THR C CG2 1 
ATOM 1614 N N   . LYS B 2 103 ? 163.239 228.221 113.068 1.00 56.21  ? 103 LYS C N   1 
ATOM 1615 C CA  . LYS B 2 103 ? 164.554 228.612 112.578 1.00 56.21  ? 103 LYS C CA  1 
ATOM 1616 C C   . LYS B 2 103 ? 164.620 230.128 112.474 1.00 56.21  ? 103 LYS C C   1 
ATOM 1617 O O   . LYS B 2 103 ? 163.806 230.740 111.774 1.00 56.21  ? 103 LYS C O   1 
ATOM 1618 C CB  . LYS B 2 103 ? 164.843 227.970 111.221 1.00 56.21  ? 103 LYS C CB  1 
ATOM 1619 N N   . VAL B 2 104 ? 165.585 230.726 113.163 1.00 59.88  ? 104 VAL C N   1 
ATOM 1620 C CA  . VAL B 2 104 ? 165.862 232.153 113.057 1.00 59.88  ? 104 VAL C CA  1 
ATOM 1621 C C   . VAL B 2 104 ? 166.941 232.340 111.997 1.00 59.88  ? 104 VAL C C   1 
ATOM 1622 O O   . VAL B 2 104 ? 168.088 231.913 112.179 1.00 59.88  ? 104 VAL C O   1 
ATOM 1623 C CB  . VAL B 2 104 ? 166.274 232.750 114.412 1.00 59.88  ? 104 VAL C CB  1 
ATOM 1624 C CG1 . VAL B 2 104 ? 165.065 232.868 115.316 1.00 59.88  ? 104 VAL C CG1 1 
ATOM 1625 C CG2 . VAL B 2 104 ? 167.317 231.882 115.092 1.00 59.88  ? 104 VAL C CG2 1 
ATOM 1626 N N   . ASP B 2 105 ? 166.574 232.959 110.879 1.00 69.12  ? 105 ASP C N   1 
ATOM 1627 C CA  . ASP B 2 105 ? 167.450 233.048 109.722 1.00 69.12  ? 105 ASP C CA  1 
ATOM 1628 C C   . ASP B 2 105 ? 167.142 234.309 108.928 1.00 69.12  ? 105 ASP C C   1 
ATOM 1629 O O   . ASP B 2 105 ? 166.123 234.971 109.138 1.00 69.12  ? 105 ASP C O   1 
ATOM 1630 C CB  . ASP B 2 105 ? 167.309 231.813 108.821 1.00 69.12  ? 105 ASP C CB  1 
ATOM 1631 C CG  . ASP B 2 105 ? 168.567 231.524 108.029 1.00 69.12  ? 105 ASP C CG  1 
ATOM 1632 O OD1 . ASP B 2 105 ? 169.671 231.655 108.598 1.00 69.12  ? 105 ASP C OD1 1 
ATOM 1633 O OD2 . ASP B 2 105 ? 168.453 231.164 106.838 1.00 69.12  ? 105 ASP C OD2 1 
ATOM 1634 N N   . ILE B 2 106 ? 168.047 234.631 108.006 1.00 76.29  ? 106 ILE C N   1 
ATOM 1635 C CA  . ILE B 2 106 ? 167.915 235.809 107.157 1.00 76.29  ? 106 ILE C CA  1 
ATOM 1636 C C   . ILE B 2 106 ? 166.872 235.547 106.079 1.00 76.29  ? 106 ILE C C   1 
ATOM 1637 O O   . ILE B 2 106 ? 166.490 234.397 105.834 1.00 76.29  ? 106 ILE C O   1 
ATOM 1638 C CB  . ILE B 2 106 ? 169.268 236.196 106.534 1.00 76.29  ? 106 ILE C CB  1 
ATOM 1639 C CG1 . ILE B 2 106 ? 169.738 235.109 105.564 1.00 76.29  ? 106 ILE C CG1 1 
ATOM 1640 C CG2 . ILE B 2 106 ? 170.306 236.430 107.620 1.00 76.29  ? 106 ILE C CG2 1 
ATOM 1641 C CD1 . ILE B 2 106 ? 170.933 235.510 104.730 1.00 76.29  ? 106 ILE C CD1 1 
ATOM 1642 N N   . LYS B 2 107 ? 166.407 236.610 105.430 1.00 80.44  ? 107 LYS C N   1 
ATOM 1643 C CA  . LYS B 2 107 ? 165.407 236.493 104.374 1.00 80.44  ? 107 LYS C CA  1 
ATOM 1644 C C   . LYS B 2 107 ? 166.004 236.835 103.012 1.00 80.44  ? 107 LYS C C   1 
ATOM 1645 O O   . LYS B 2 107 ? 165.338 237.429 102.164 1.00 80.44  ? 107 LYS C O   1 
ATOM 1646 C CB  . LYS B 2 107 ? 164.210 237.400 104.667 1.00 80.44  ? 107 LYS C CB  1 
ATOM 1647 N N   . THR C 3 1   ? 164.630 156.101 156.932 1.00 54.76  ? 333 THR A N   1 
ATOM 1648 C CA  . THR C 3 1   ? 165.182 154.769 156.722 1.00 54.76  ? 333 THR A CA  1 
ATOM 1649 C C   . THR C 3 1   ? 165.630 154.581 155.275 1.00 54.76  ? 333 THR A C   1 
ATOM 1650 O O   . THR C 3 1   ? 166.670 153.979 155.013 1.00 54.76  ? 333 THR A O   1 
ATOM 1651 C CB  . THR C 3 1   ? 164.162 153.677 157.085 1.00 54.76  ? 333 THR A CB  1 
ATOM 1652 O OG1 . THR C 3 1   ? 163.581 153.971 158.361 1.00 54.76  ? 333 THR A OG1 1 
ATOM 1653 C CG2 . THR C 3 1   ? 164.837 152.317 157.144 1.00 54.76  ? 333 THR A CG2 1 
ATOM 1654 N N   . ASN C 3 2   ? 164.838 155.098 154.339 1.00 56.70  ? 334 ASN A N   1 
ATOM 1655 C CA  . ASN C 3 2   ? 165.183 155.020 152.929 1.00 56.70  ? 334 ASN A CA  1 
ATOM 1656 C C   . ASN C 3 2   ? 166.136 156.152 152.548 1.00 56.70  ? 334 ASN A C   1 
ATOM 1657 O O   . ASN C 3 2   ? 166.321 157.124 153.284 1.00 56.70  ? 334 ASN A O   1 
ATOM 1658 C CB  . ASN C 3 2   ? 163.924 155.066 152.066 1.00 56.70  ? 334 ASN A CB  1 
ATOM 1659 C CG  . ASN C 3 2   ? 163.098 156.310 152.308 1.00 56.70  ? 334 ASN A CG  1 
ATOM 1660 O OD1 . ASN C 3 2   ? 163.266 156.992 153.318 1.00 56.70  ? 334 ASN A OD1 1 
ATOM 1661 N ND2 . ASN C 3 2   ? 162.201 156.614 151.379 1.00 56.70  ? 334 ASN A ND2 1 
ATOM 1662 N N   . LEU C 3 3   ? 166.745 156.015 151.373 1.00 56.45  ? 335 LEU A N   1 
ATOM 1663 C CA  . LEU C 3 3   ? 167.735 156.980 150.915 1.00 56.45  ? 335 LEU A CA  1 
ATOM 1664 C C   . LEU C 3 3   ? 167.063 158.247 150.402 1.00 56.45  ? 335 LEU A C   1 
ATOM 1665 O O   . LEU C 3 3   ? 166.054 158.191 149.694 1.00 56.45  ? 335 LEU A O   1 
ATOM 1666 C CB  . LEU C 3 3   ? 168.613 156.375 149.818 1.00 56.45  ? 335 LEU A CB  1 
ATOM 1667 C CG  . LEU C 3 3   ? 169.802 155.506 150.246 1.00 56.45  ? 335 LEU A CG  1 
ATOM 1668 C CD1 . LEU C 3 3   ? 170.814 156.335 151.026 1.00 56.45  ? 335 LEU A CD1 1 
ATOM 1669 C CD2 . LEU C 3 3   ? 169.376 154.276 151.041 1.00 56.45  ? 335 LEU A CD2 1 
ATOM 1670 N N   . CYS C 3 4   ? 167.635 159.393 150.763 1.00 53.87  ? 336 CYS A N   1 
ATOM 1671 C CA  . CYS C 3 4   ? 167.068 160.671 150.372 1.00 53.87  ? 336 CYS A CA  1 
ATOM 1672 C C   . CYS C 3 4   ? 167.251 160.905 148.874 1.00 53.87  ? 336 CYS A C   1 
ATOM 1673 O O   . CYS C 3 4   ? 168.245 160.472 148.285 1.00 53.87  ? 336 CYS A O   1 
ATOM 1674 C CB  . CYS C 3 4   ? 167.719 161.805 151.156 1.00 53.87  ? 336 CYS A CB  1 
ATOM 1675 S SG  . CYS C 3 4   ? 167.247 161.852 152.892 1.00 53.87  ? 336 CYS A SG  1 
ATOM 1676 N N   . PRO C 3 5   ? 166.306 161.593 148.235 1.00 48.33  ? 337 PRO A N   1 
ATOM 1677 C CA  . PRO C 3 5   ? 166.402 161.840 146.783 1.00 48.33  ? 337 PRO A CA  1 
ATOM 1678 C C   . PRO C 3 5   ? 167.188 163.105 146.452 1.00 48.33  ? 337 PRO A C   1 
ATOM 1679 O O   . PRO C 3 5   ? 166.653 164.111 145.968 1.00 48.33  ? 337 PRO A O   1 
ATOM 1680 C CB  . PRO C 3 5   ? 164.931 161.938 146.376 1.00 48.33  ? 337 PRO A CB  1 
ATOM 1681 C CG  . PRO C 3 5   ? 164.267 162.549 147.572 1.00 48.33  ? 337 PRO A CG  1 
ATOM 1682 C CD  . PRO C 3 5   ? 165.053 162.127 148.798 1.00 48.33  ? 337 PRO A CD  1 
ATOM 1683 N N   . PHE C 3 6   ? 168.495 163.070 146.723 1.00 41.25  ? 338 PHE A N   1 
ATOM 1684 C CA  . PHE C 3 6   ? 169.361 164.159 146.289 1.00 41.25  ? 338 PHE A CA  1 
ATOM 1685 C C   . PHE C 3 6   ? 169.563 164.155 144.781 1.00 41.25  ? 338 PHE A C   1 
ATOM 1686 O O   . PHE C 3 6   ? 169.945 165.186 144.217 1.00 41.25  ? 338 PHE A O   1 
ATOM 1687 C CB  . PHE C 3 6   ? 170.713 164.083 146.997 1.00 41.25  ? 338 PHE A CB  1 
ATOM 1688 C CG  . PHE C 3 6   ? 170.718 164.710 148.359 1.00 41.25  ? 338 PHE A CG  1 
ATOM 1689 C CD1 . PHE C 3 6   ? 170.361 166.035 148.526 1.00 41.25  ? 338 PHE A CD1 1 
ATOM 1690 C CD2 . PHE C 3 6   ? 171.085 163.977 149.473 1.00 41.25  ? 338 PHE A CD2 1 
ATOM 1691 C CE1 . PHE C 3 6   ? 170.367 166.615 149.777 1.00 41.25  ? 338 PHE A CE1 1 
ATOM 1692 C CE2 . PHE C 3 6   ? 171.091 164.552 150.725 1.00 41.25  ? 338 PHE A CE2 1 
ATOM 1693 C CZ  . PHE C 3 6   ? 170.733 165.873 150.877 1.00 41.25  ? 338 PHE A CZ  1 
ATOM 1694 N N   . GLY C 3 7   ? 169.329 163.019 144.123 1.00 41.95  ? 339 GLY A N   1 
ATOM 1695 C CA  . GLY C 3 7   ? 169.347 162.981 142.673 1.00 41.95  ? 339 GLY A CA  1 
ATOM 1696 C C   . GLY C 3 7   ? 168.164 163.672 142.036 1.00 41.95  ? 339 GLY A C   1 
ATOM 1697 O O   . GLY C 3 7   ? 168.249 164.081 140.874 1.00 41.95  ? 339 GLY A O   1 
ATOM 1698 N N   . GLU C 3 8   ? 167.058 163.811 142.770 1.00 42.28  ? 340 GLU A N   1 
ATOM 1699 C CA  . GLU C 3 8   ? 165.927 164.585 142.277 1.00 42.28  ? 340 GLU A CA  1 
ATOM 1700 C C   . GLU C 3 8   ? 166.221 166.078 142.268 1.00 42.28  ? 340 GLU A C   1 
ATOM 1701 O O   . GLU C 3 8   ? 165.461 166.843 141.667 1.00 42.28  ? 340 GLU A O   1 
ATOM 1702 C CB  . GLU C 3 8   ? 164.685 164.307 143.126 1.00 42.28  ? 340 GLU A CB  1 
ATOM 1703 C CG  . GLU C 3 8   ? 164.064 162.938 142.901 1.00 42.28  ? 340 GLU A CG  1 
ATOM 1704 C CD  . GLU C 3 8   ? 164.066 162.526 141.443 1.00 42.28  ? 340 GLU A CD  1 
ATOM 1705 O OE1 . GLU C 3 8   ? 163.244 163.062 140.672 1.00 42.28  ? 340 GLU A OE1 1 
ATOM 1706 O OE2 . GLU C 3 8   ? 164.887 161.662 141.069 1.00 42.28  ? 340 GLU A OE2 1 
ATOM 1707 N N   . VAL C 3 9   ? 167.299 166.505 142.921 1.00 36.12  ? 341 VAL A N   1 
ATOM 1708 C CA  . VAL C 3 9   ? 167.693 167.910 142.975 1.00 36.12  ? 341 VAL A CA  1 
ATOM 1709 C C   . VAL C 3 9   ? 168.941 168.164 142.136 1.00 36.12  ? 341 VAL A C   1 
ATOM 1710 O O   . VAL C 3 9   ? 168.905 168.929 141.172 1.00 36.12  ? 341 VAL A O   1 
ATOM 1711 C CB  . VAL C 3 9   ? 167.897 168.373 144.435 1.00 36.12  ? 341 VAL A CB  1 
ATOM 1712 C CG1 . VAL C 3 9   ? 167.986 169.886 144.504 1.00 36.12  ? 341 VAL A CG1 1 
ATOM 1713 C CG2 . VAL C 3 9   ? 166.773 167.858 145.315 1.00 36.12  ? 341 VAL A CG2 1 
ATOM 1714 N N   . PHE C 3 10  ? 170.058 167.525 142.487 1.00 32.42  ? 342 PHE A N   1 
ATOM 1715 C CA  . PHE C 3 10  ? 171.312 167.793 141.791 1.00 32.42  ? 342 PHE A CA  1 
ATOM 1716 C C   . PHE C 3 10  ? 171.265 167.309 140.348 1.00 32.42  ? 342 PHE A C   1 
ATOM 1717 O O   . PHE C 3 10  ? 171.737 168.001 139.441 1.00 32.42  ? 342 PHE A O   1 
ATOM 1718 C CB  . PHE C 3 10  ? 172.478 167.148 142.538 1.00 32.42  ? 342 PHE A CB  1 
ATOM 1719 C CG  . PHE C 3 10  ? 172.755 167.770 143.875 1.00 32.42  ? 342 PHE A CG  1 
ATOM 1720 C CD1 . PHE C 3 10  ? 171.895 167.573 144.939 1.00 32.42  ? 342 PHE A CD1 1 
ATOM 1721 C CD2 . PHE C 3 10  ? 173.870 168.560 144.064 1.00 32.42  ? 342 PHE A CD2 1 
ATOM 1722 C CE1 . PHE C 3 10  ? 172.145 168.146 146.163 1.00 32.42  ? 342 PHE A CE1 1 
ATOM 1723 C CE2 . PHE C 3 10  ? 174.123 169.134 145.288 1.00 32.42  ? 342 PHE A CE2 1 
ATOM 1724 C CZ  . PHE C 3 10  ? 173.258 168.927 146.336 1.00 32.42  ? 342 PHE A CZ  1 
ATOM 1725 N N   . ASN C 3 11  ? 170.700 166.127 140.114 1.00 40.10  ? 343 ASN A N   1 
ATOM 1726 C CA  . ASN C 3 11  ? 170.594 165.570 138.774 1.00 40.10  ? 343 ASN A CA  1 
ATOM 1727 C C   . ASN C 3 11  ? 169.303 165.974 138.072 1.00 40.10  ? 343 ASN A C   1 
ATOM 1728 O O   . ASN C 3 11  ? 168.876 165.287 137.137 1.00 40.10  ? 343 ASN A O   1 
ATOM 1729 C CB  . ASN C 3 11  ? 170.715 164.046 138.824 1.00 40.10  ? 343 ASN A CB  1 
ATOM 1730 C CG  . ASN C 3 11  ? 172.152 163.579 138.945 1.00 40.10  ? 343 ASN A CG  1 
ATOM 1731 O OD1 . ASN C 3 11  ? 173.080 164.289 138.560 1.00 40.10  ? 343 ASN A OD1 1 
ATOM 1732 N ND2 . ASN C 3 11  ? 172.343 162.380 139.483 1.00 40.10  ? 343 ASN A ND2 1 
ATOM 1733 N N   . ALA C 3 12  ? 168.675 167.066 138.502 1.00 42.03  ? 344 ALA A N   1 
ATOM 1734 C CA  . ALA C 3 12  ? 167.462 167.539 137.850 1.00 42.03  ? 344 ALA A CA  1 
ATOM 1735 C C   . ALA C 3 12  ? 167.769 168.018 136.438 1.00 42.03  ? 344 ALA A C   1 
ATOM 1736 O O   . ALA C 3 12  ? 168.862 168.518 136.157 1.00 42.03  ? 344 ALA A O   1 
ATOM 1737 C CB  . ALA C 3 12  ? 166.824 168.666 138.661 1.00 42.03  ? 344 ALA A CB  1 
ATOM 1738 N N   . THR C 3 13  ? 166.793 167.859 135.542 1.00 48.36  ? 345 THR A N   1 
ATOM 1739 C CA  . THR C 3 13  ? 166.998 168.229 134.148 1.00 48.36  ? 345 THR A CA  1 
ATOM 1740 C C   . THR C 3 13  ? 167.168 169.731 133.959 1.00 48.36  ? 345 THR A C   1 
ATOM 1741 O O   . THR C 3 13  ? 167.818 170.148 132.995 1.00 48.36  ? 345 THR A O   1 
ATOM 1742 C CB  . THR C 3 13  ? 165.838 167.722 133.288 1.00 48.36  ? 345 THR A CB  1 
ATOM 1743 O OG1 . THR C 3 13  ? 166.064 168.079 131.919 1.00 48.36  ? 345 THR A OG1 1 
ATOM 1744 C CG2 . THR C 3 13  ? 164.517 168.315 133.756 1.00 48.36  ? 345 THR A CG2 1 
ATOM 1745 N N   . ARG C 3 14  ? 166.605 170.550 134.847 1.00 46.11  ? 346 ARG A N   1 
ATOM 1746 C CA  . ARG C 3 14  ? 166.759 171.993 134.752 1.00 46.11  ? 346 ARG A CA  1 
ATOM 1747 C C   . ARG C 3 14  ? 166.416 172.629 136.091 1.00 46.11  ? 346 ARG A C   1 
ATOM 1748 O O   . ARG C 3 14  ? 165.695 172.048 136.906 1.00 46.11  ? 346 ARG A O   1 
ATOM 1749 C CB  . ARG C 3 14  ? 165.879 172.583 133.643 1.00 46.11  ? 346 ARG A CB  1 
ATOM 1750 C CG  . ARG C 3 14  ? 164.465 172.031 133.603 1.00 46.11  ? 346 ARG A CG  1 
ATOM 1751 C CD  . ARG C 3 14  ? 163.495 173.058 133.044 1.00 46.11  ? 346 ARG A CD  1 
ATOM 1752 N NE  . ARG C 3 14  ? 162.126 172.559 133.006 1.00 46.11  ? 346 ARG A NE  1 
ATOM 1753 C CZ  . ARG C 3 14  ? 161.048 173.323 133.113 1.00 46.11  ? 346 ARG A CZ  1 
ATOM 1754 N NH1 . ARG C 3 14  ? 161.142 174.633 133.272 1.00 46.11  ? 346 ARG A NH1 1 
ATOM 1755 N NH2 . ARG C 3 14  ? 159.845 172.758 133.059 1.00 46.11  ? 346 ARG A NH2 1 
ATOM 1756 N N   . PHE C 3 15  ? 166.940 173.833 136.304 1.00 31.00  ? 347 PHE A N   1 
ATOM 1757 C CA  . PHE C 3 15  ? 166.704 174.602 137.518 1.00 31.00  ? 347 PHE A CA  1 
ATOM 1758 C C   . PHE C 3 15  ? 165.920 175.859 137.182 1.00 31.00  ? 347 PHE A C   1 
ATOM 1759 O O   . PHE C 3 15  ? 166.152 176.481 136.140 1.00 31.00  ? 347 PHE A O   1 
ATOM 1760 C CB  . PHE C 3 15  ? 168.014 174.984 138.206 1.00 31.00  ? 347 PHE A CB  1 
ATOM 1761 C CG  . PHE C 3 15  ? 168.686 173.847 138.905 1.00 31.00  ? 347 PHE A CG  1 
ATOM 1762 C CD1 . PHE C 3 15  ? 168.006 172.670 139.146 1.00 31.00  ? 347 PHE A CD1 1 
ATOM 1763 C CD2 . PHE C 3 15  ? 169.991 173.961 139.337 1.00 31.00  ? 347 PHE A CD2 1 
ATOM 1764 C CE1 . PHE C 3 15  ? 168.620 171.626 139.796 1.00 31.00  ? 347 PHE A CE1 1 
ATOM 1765 C CE2 . PHE C 3 15  ? 170.611 172.920 139.985 1.00 31.00  ? 347 PHE A CE2 1 
ATOM 1766 C CZ  . PHE C 3 15  ? 169.925 171.750 140.215 1.00 31.00  ? 347 PHE A CZ  1 
ATOM 1767 N N   . ALA C 3 16  ? 164.998 176.225 138.065 1.00 30.21  ? 348 ALA A N   1 
ATOM 1768 C CA  . ALA C 3 16  ? 164.270 177.473 137.907 1.00 30.21  ? 348 ALA A CA  1 
ATOM 1769 C C   . ALA C 3 16  ? 165.218 178.653 138.060 1.00 30.21  ? 348 ALA A C   1 
ATOM 1770 O O   . ALA C 3 16  ? 166.232 178.568 138.758 1.00 30.21  ? 348 ALA A O   1 
ATOM 1771 C CB  . ALA C 3 16  ? 163.140 177.565 138.931 1.00 30.21  ? 348 ALA A CB  1 
ATOM 1772 N N   . SER C 3 17  ? 164.884 179.756 137.397 1.00 33.02  ? 349 SER A N   1 
ATOM 1773 C CA  . SER C 3 17  ? 165.705 180.954 137.461 1.00 33.02  ? 349 SER A CA  1 
ATOM 1774 C C   . SER C 3 17  ? 165.822 181.449 138.900 1.00 33.02  ? 349 SER A C   1 
ATOM 1775 O O   . SER C 3 17  ? 165.070 181.047 139.790 1.00 33.02  ? 349 SER A O   1 
ATOM 1776 C CB  . SER C 3 17  ? 165.121 182.041 136.563 1.00 33.02  ? 349 SER A CB  1 
ATOM 1777 O OG  . SER C 3 17  ? 163.735 182.198 136.799 1.00 33.02  ? 349 SER A OG  1 
ATOM 1778 N N   . VAL C 3 18  ? 166.789 182.340 139.121 1.00 31.30  ? 350 VAL A N   1 
ATOM 1779 C CA  . VAL C 3 18  ? 167.154 182.713 140.483 1.00 31.30  ? 350 VAL A CA  1 
ATOM 1780 C C   . VAL C 3 18  ? 166.023 183.471 141.171 1.00 31.30  ? 350 VAL A C   1 
ATOM 1781 O O   . VAL C 3 18  ? 165.820 183.332 142.381 1.00 31.30  ? 350 VAL A O   1 
ATOM 1782 C CB  . VAL C 3 18  ? 168.468 183.514 140.483 1.00 31.30  ? 350 VAL A CB  1 
ATOM 1783 C CG1 . VAL C 3 18  ? 168.326 184.772 139.663 1.00 31.30  ? 350 VAL A CG1 1 
ATOM 1784 C CG2 . VAL C 3 18  ? 168.885 183.845 141.906 1.00 31.30  ? 350 VAL A CG2 1 
ATOM 1785 N N   . TYR C 3 19  ? 165.267 184.280 140.425 1.00 38.02  ? 351 TYR A N   1 
ATOM 1786 C CA  . TYR C 3 19  ? 164.218 185.074 141.059 1.00 38.02  ? 351 TYR A CA  1 
ATOM 1787 C C   . TYR C 3 19  ? 163.059 184.218 141.554 1.00 38.02  ? 351 TYR A C   1 
ATOM 1788 O O   . TYR C 3 19  ? 162.226 184.710 142.321 1.00 38.02  ? 351 TYR A O   1 
ATOM 1789 C CB  . TYR C 3 19  ? 163.704 186.146 140.096 1.00 38.02  ? 351 TYR A CB  1 
ATOM 1790 C CG  . TYR C 3 19  ? 162.576 185.700 139.196 1.00 38.02  ? 351 TYR A CG  1 
ATOM 1791 C CD1 . TYR C 3 19  ? 162.818 184.906 138.087 1.00 38.02  ? 351 TYR A CD1 1 
ATOM 1792 C CD2 . TYR C 3 19  ? 161.268 186.087 139.450 1.00 38.02  ? 351 TYR A CD2 1 
ATOM 1793 C CE1 . TYR C 3 19  ? 161.788 184.503 137.260 1.00 38.02  ? 351 TYR A CE1 1 
ATOM 1794 C CE2 . TYR C 3 19  ? 160.233 185.688 138.630 1.00 38.02  ? 351 TYR A CE2 1 
ATOM 1795 C CZ  . TYR C 3 19  ? 160.499 184.897 137.537 1.00 38.02  ? 351 TYR A CZ  1 
ATOM 1796 O OH  . TYR C 3 19  ? 159.470 184.497 136.717 1.00 38.02  ? 351 TYR A OH  1 
ATOM 1797 N N   . ALA C 3 20  ? 162.990 182.956 141.140 1.00 34.57  ? 352 ALA A N   1 
ATOM 1798 C CA  . ALA C 3 20  ? 161.948 182.019 141.546 1.00 34.57  ? 352 ALA A CA  1 
ATOM 1799 C C   . ALA C 3 20  ? 162.566 180.681 141.924 1.00 34.57  ? 352 ALA A C   1 
ATOM 1800 O O   . ALA C 3 20  ? 162.163 179.623 141.436 1.00 34.57  ? 352 ALA A O   1 
ATOM 1801 C CB  . ALA C 3 20  ? 160.911 181.841 140.442 1.00 34.57  ? 352 ALA A CB  1 
ATOM 1802 N N   . TRP C 3 21  ? 163.577 180.722 142.793 1.00 33.64  ? 353 TRP A N   1 
ATOM 1803 C CA  . TRP C 3 21  ? 164.354 179.530 143.114 1.00 33.64  ? 353 TRP A CA  1 
ATOM 1804 C C   . TRP C 3 21  ? 163.465 178.411 143.639 1.00 33.64  ? 353 TRP A C   1 
ATOM 1805 O O   . TRP C 3 21  ? 162.593 178.635 144.482 1.00 33.64  ? 353 TRP A O   1 
ATOM 1806 C CB  . TRP C 3 21  ? 165.433 179.862 144.144 1.00 33.64  ? 353 TRP A CB  1 
ATOM 1807 C CG  . TRP C 3 21  ? 165.048 180.914 145.133 1.00 33.64  ? 353 TRP A CG  1 
ATOM 1808 C CD1 . TRP C 3 21  ? 165.252 182.254 145.019 1.00 33.64  ? 353 TRP A CD1 1 
ATOM 1809 C CD2 . TRP C 3 21  ? 164.404 180.714 146.395 1.00 33.64  ? 353 TRP A CD2 1 
ATOM 1810 N NE1 . TRP C 3 21  ? 164.771 182.905 146.126 1.00 33.64  ? 353 TRP A NE1 1 
ATOM 1811 C CE2 . TRP C 3 21  ? 164.245 181.980 146.988 1.00 33.64  ? 353 TRP A CE2 1 
ATOM 1812 C CE3 . TRP C 3 21  ? 163.944 179.587 147.081 1.00 33.64  ? 353 TRP A CE3 1 
ATOM 1813 C CZ2 . TRP C 3 21  ? 163.645 182.152 148.232 1.00 33.64  ? 353 TRP A CZ2 1 
ATOM 1814 C CZ3 . TRP C 3 21  ? 163.346 179.761 148.315 1.00 33.64  ? 353 TRP A CZ3 1 
ATOM 1815 C CH2 . TRP C 3 21  ? 163.204 181.032 148.878 1.00 33.64  ? 353 TRP A CH2 1 
ATOM 1816 N N   . ASN C 3 22  ? 163.689 177.203 143.130 1.00 34.55  ? 354 ASN A N   1 
ATOM 1817 C CA  . ASN C 3 22  ? 162.920 176.051 143.574 1.00 34.55  ? 354 ASN A CA  1 
ATOM 1818 C C   . ASN C 3 22  ? 163.292 175.686 145.005 1.00 34.55  ? 354 ASN A C   1 
ATOM 1819 O O   . ASN C 3 22  ? 164.457 175.750 145.401 1.00 34.55  ? 354 ASN A O   1 
ATOM 1820 C CB  . ASN C 3 22  ? 163.161 174.862 142.647 1.00 34.55  ? 354 ASN A CB  1 
ATOM 1821 C CG  . ASN C 3 22  ? 162.121 173.775 142.813 1.00 34.55  ? 354 ASN A CG  1 
ATOM 1822 O OD1 . ASN C 3 22  ? 161.091 173.979 143.455 1.00 34.55  ? 354 ASN A OD1 1 
ATOM 1823 N ND2 . ASN C 3 22  ? 162.383 172.611 142.231 1.00 34.55  ? 354 ASN A ND2 1 
ATOM 1824 N N   . ARG C 3 23  ? 162.287 175.287 145.782 1.00 35.88  ? 355 ARG A N   1 
ATOM 1825 C CA  . ARG C 3 23  ? 162.458 174.959 147.198 1.00 35.88  ? 355 ARG A CA  1 
ATOM 1826 C C   . ARG C 3 23  ? 161.974 173.529 147.411 1.00 35.88  ? 355 ARG A C   1 
ATOM 1827 O O   . ARG C 3 23  ? 160.813 173.302 147.760 1.00 35.88  ? 355 ARG A O   1 
ATOM 1828 C CB  . ARG C 3 23  ? 161.700 175.945 148.078 1.00 35.88  ? 355 ARG A CB  1 
ATOM 1829 C CG  . ARG C 3 23  ? 161.883 175.729 149.569 1.00 35.88  ? 355 ARG A CG  1 
ATOM 1830 C CD  . ARG C 3 23  ? 163.266 176.153 150.008 1.00 35.88  ? 355 ARG A CD  1 
ATOM 1831 N NE  . ARG C 3 23  ? 163.355 176.328 151.451 1.00 35.88  ? 355 ARG A NE  1 
ATOM 1832 C CZ  . ARG C 3 23  ? 163.091 177.462 152.085 1.00 35.88  ? 355 ARG A CZ  1 
ATOM 1833 N NH1 . ARG C 3 23  ? 162.699 178.542 151.432 1.00 35.88  ? 355 ARG A NH1 1 
ATOM 1834 N NH2 . ARG C 3 23  ? 163.222 177.512 153.407 1.00 35.88  ? 355 ARG A NH2 1 
ATOM 1835 N N   . LYS C 3 24  ? 162.867 172.566 147.208 1.00 40.80  ? 356 LYS A N   1 
ATOM 1836 C CA  . LYS C 3 24  ? 162.524 171.166 147.406 1.00 40.80  ? 356 LYS A CA  1 
ATOM 1837 C C   . LYS C 3 24  ? 162.703 170.793 148.870 1.00 40.80  ? 356 LYS A C   1 
ATOM 1838 O O   . LYS C 3 24  ? 163.757 171.046 149.460 1.00 40.80  ? 356 LYS A O   1 
ATOM 1839 C CB  . LYS C 3 24  ? 163.389 170.272 146.520 1.00 40.80  ? 356 LYS A CB  1 
ATOM 1840 C CG  . LYS C 3 24  ? 163.114 168.787 146.687 1.00 40.80  ? 356 LYS A CG  1 
ATOM 1841 C CD  . LYS C 3 24  ? 161.727 168.424 146.187 1.00 40.80  ? 356 LYS A CD  1 
ATOM 1842 C CE  . LYS C 3 24  ? 161.468 166.931 146.308 1.00 40.80  ? 356 LYS A CE  1 
ATOM 1843 N NZ  . LYS C 3 24  ? 161.343 166.501 147.728 1.00 40.80  ? 356 LYS A NZ  1 
ATOM 1844 N N   . ARG C 3 25  ? 161.671 170.196 149.455 1.00 49.47  ? 357 ARG A N   1 
ATOM 1845 C CA  . ARG C 3 25  ? 161.698 169.770 150.847 1.00 49.47  ? 357 ARG A CA  1 
ATOM 1846 C C   . ARG C 3 25  ? 162.094 168.303 150.917 1.00 49.47  ? 357 ARG A C   1 
ATOM 1847 O O   . ARG C 3 25  ? 161.512 167.464 150.222 1.00 49.47  ? 357 ARG A O   1 
ATOM 1848 C CB  . ARG C 3 25  ? 160.339 169.984 151.513 1.00 49.47  ? 357 ARG A CB  1 
ATOM 1849 C CG  . ARG C 3 25  ? 160.247 169.407 152.914 1.00 49.47  ? 357 ARG A CG  1 
ATOM 1850 C CD  . ARG C 3 25  ? 158.908 169.723 153.554 1.00 49.47  ? 357 ARG A CD  1 
ATOM 1851 N NE  . ARG C 3 25  ? 158.855 169.282 154.943 1.00 49.47  ? 357 ARG A NE  1 
ATOM 1852 C CZ  . ARG C 3 25  ? 158.549 168.050 155.325 1.00 49.47  ? 357 ARG A CZ  1 
ATOM 1853 N NH1 . ARG C 3 25  ? 158.258 167.106 154.446 1.00 49.47  ? 357 ARG A NH1 1 
ATOM 1854 N NH2 . ARG C 3 25  ? 158.535 167.758 156.623 1.00 49.47  ? 357 ARG A NH2 1 
ATOM 1855 N N   . ILE C 3 26  ? 163.083 168.000 151.752 1.00 48.78  ? 358 ILE A N   1 
ATOM 1856 C CA  . ILE C 3 26  ? 163.604 166.651 151.920 1.00 48.78  ? 358 ILE A CA  1 
ATOM 1857 C C   . ILE C 3 26  ? 163.436 166.265 153.382 1.00 48.78  ? 358 ILE A C   1 
ATOM 1858 O O   . ILE C 3 26  ? 163.934 166.963 154.277 1.00 48.78  ? 358 ILE A O   1 
ATOM 1859 C CB  . ILE C 3 26  ? 165.075 166.551 151.486 1.00 48.78  ? 358 ILE A CB  1 
ATOM 1860 C CG1 . ILE C 3 26  ? 165.265 167.183 150.107 1.00 48.78  ? 358 ILE A CG1 1 
ATOM 1861 C CG2 . ILE C 3 26  ? 165.524 165.107 151.459 1.00 48.78  ? 358 ILE A CG2 1 
ATOM 1862 C CD1 . ILE C 3 26  ? 166.697 167.185 149.633 1.00 48.78  ? 358 ILE A CD1 1 
ATOM 1863 N N   . SER C 3 27  ? 162.731 165.160 153.617 1.00 56.83  ? 359 SER A N   1 
ATOM 1864 C CA  . SER C 3 27  ? 162.489 164.638 154.954 1.00 56.83  ? 359 SER A CA  1 
ATOM 1865 C C   . SER C 3 27  ? 162.024 163.195 154.821 1.00 56.83  ? 359 SER A C   1 
ATOM 1866 O O   . SER C 3 27  ? 161.815 162.690 153.715 1.00 56.83  ? 359 SER A O   1 
ATOM 1867 C CB  . SER C 3 27  ? 161.460 165.483 155.712 1.00 56.83  ? 359 SER A CB  1 
ATOM 1868 O OG  . SER C 3 27  ? 162.038 166.686 156.186 1.00 56.83  ? 359 SER A OG  1 
ATOM 1869 N N   . ASN C 3 28  ? 161.862 162.536 155.971 1.00 58.40  ? 360 ASN A N   1 
ATOM 1870 C CA  . ASN C 3 28  ? 161.429 161.137 156.033 1.00 58.40  ? 360 ASN A CA  1 
ATOM 1871 C C   . ASN C 3 28  ? 162.339 160.235 155.201 1.00 58.40  ? 360 ASN A C   1 
ATOM 1872 O O   . ASN C 3 28  ? 161.877 159.347 154.483 1.00 58.40  ? 360 ASN A O   1 
ATOM 1873 C CB  . ASN C 3 28  ? 159.970 160.988 155.596 1.00 58.40  ? 360 ASN A CB  1 
ATOM 1874 C CG  . ASN C 3 28  ? 159.006 161.657 156.554 1.00 58.40  ? 360 ASN A CG  1 
ATOM 1875 O OD1 . ASN C 3 28  ? 159.417 162.344 157.488 1.00 58.40  ? 360 ASN A OD1 1 
ATOM 1876 N ND2 . ASN C 3 28  ? 157.713 161.459 156.325 1.00 58.40  ? 360 ASN A ND2 1 
ATOM 1877 N N   . CYS C 3 29  ? 163.643 160.468 155.301 1.00 55.21  ? 361 CYS A N   1 
ATOM 1878 C CA  . CYS C 3 29  ? 164.629 159.715 154.539 1.00 55.21  ? 361 CYS A CA  1 
ATOM 1879 C C   . CYS C 3 29  ? 165.982 159.845 155.223 1.00 55.21  ? 361 CYS A C   1 
ATOM 1880 O O   . CYS C 3 29  ? 166.187 160.708 156.078 1.00 55.21  ? 361 CYS A O   1 
ATOM 1881 C CB  . CYS C 3 29  ? 164.677 160.191 153.084 1.00 55.21  ? 361 CYS A CB  1 
ATOM 1882 S SG  . CYS C 3 29  ? 165.220 161.903 152.861 1.00 55.21  ? 361 CYS A SG  1 
ATOM 1883 N N   . VAL C 3 30  ? 166.905 158.967 154.841 1.00 51.80  ? 362 VAL A N   1 
ATOM 1884 C CA  . VAL C 3 30  ? 168.258 158.960 155.383 1.00 51.80  ? 362 VAL A CA  1 
ATOM 1885 C C   . VAL C 3 30  ? 169.180 159.591 154.351 1.00 51.80  ? 362 VAL A C   1 
ATOM 1886 O O   . VAL C 3 30  ? 169.245 159.135 153.203 1.00 51.80  ? 362 VAL A O   1 
ATOM 1887 C CB  . VAL C 3 30  ? 168.715 157.537 155.741 1.00 51.80  ? 362 VAL A CB  1 
ATOM 1888 C CG1 . VAL C 3 30  ? 170.227 157.482 155.868 1.00 51.80  ? 362 VAL A CG1 1 
ATOM 1889 C CG2 . VAL C 3 30  ? 168.059 157.084 157.032 1.00 51.80  ? 362 VAL A CG2 1 
ATOM 1890 N N   . ALA C 3 31  ? 169.889 160.640 154.755 1.00 47.61  ? 363 ALA A N   1 
ATOM 1891 C CA  . ALA C 3 31  ? 170.705 161.431 153.848 1.00 47.61  ? 363 ALA A CA  1 
ATOM 1892 C C   . ALA C 3 31  ? 172.165 161.009 153.933 1.00 47.61  ? 363 ALA A C   1 
ATOM 1893 O O   . ALA C 3 31  ? 172.694 160.777 155.023 1.00 47.61  ? 363 ALA A O   1 
ATOM 1894 C CB  . ALA C 3 31  ? 170.576 162.922 154.162 1.00 47.61  ? 363 ALA A CB  1 
ATOM 1895 N N   . ASP C 3 32  ? 172.809 160.911 152.772 1.00 47.91  ? 364 ASP A N   1 
ATOM 1896 C CA  . ASP C 3 32  ? 174.223 160.557 152.658 1.00 47.91  ? 364 ASP A CA  1 
ATOM 1897 C C   . ASP C 3 32  ? 174.974 161.657 151.904 1.00 47.91  ? 364 ASP A C   1 
ATOM 1898 O O   . ASP C 3 32  ? 175.225 161.572 150.701 1.00 47.91  ? 364 ASP A O   1 
ATOM 1899 C CB  . ASP C 3 32  ? 174.372 159.129 151.995 1.00 47.91  ? 364 ASP A CB  1 
ATOM 1900 C CG  . ASP C 3 32  ? 173.815 159.057 150.575 1.00 47.91  ? 364 ASP A CG  1 
ATOM 1901 O OD1 . ASP C 3 32  ? 173.264 160.060 150.073 1.00 47.91  ? 364 ASP A OD1 1 
ATOM 1902 O OD2 . ASP C 3 32  ? 173.932 157.979 149.955 1.00 47.91  ? 364 ASP A OD2 1 
ATOM 1903 N N   . TYR C 3 33  ? 175.377 162.690 152.644 1.00 44.60  ? 365 TYR A N   1 
ATOM 1904 C CA  . TYR C 3 33  ? 176.042 163.838 152.040 1.00 44.60  ? 365 TYR A CA  1 
ATOM 1905 C C   . TYR C 3 33  ? 177.454 163.527 151.563 1.00 44.60  ? 365 TYR A C   1 
ATOM 1906 O O   . TYR C 3 33  ? 178.043 164.356 150.861 1.00 44.60  ? 365 TYR A O   1 
ATOM 1907 C CB  . TYR C 3 33  ? 176.091 165.006 153.026 1.00 44.60  ? 365 TYR A CB  1 
ATOM 1908 C CG  . TYR C 3 33  ? 174.786 165.285 153.733 1.00 44.60  ? 365 TYR A CG  1 
ATOM 1909 C CD1 . TYR C 3 33  ? 173.915 166.258 153.264 1.00 44.60  ? 365 TYR A CD1 1 
ATOM 1910 C CD2 . TYR C 3 33  ? 174.436 164.595 154.885 1.00 44.60  ? 365 TYR A CD2 1 
ATOM 1911 C CE1 . TYR C 3 33  ? 172.726 166.521 153.911 1.00 44.60  ? 365 TYR A CE1 1 
ATOM 1912 C CE2 . TYR C 3 33  ? 173.250 164.852 155.538 1.00 44.60  ? 365 TYR A CE2 1 
ATOM 1913 C CZ  . TYR C 3 33  ? 172.400 165.815 155.047 1.00 44.60  ? 365 TYR A CZ  1 
ATOM 1914 O OH  . TYR C 3 33  ? 171.218 166.070 155.700 1.00 44.60  ? 365 TYR A OH  1 
ATOM 1915 N N   . SER C 3 34  ? 178.005 162.365 151.920 1.00 50.57  ? 366 SER A N   1 
ATOM 1916 C CA  . SER C 3 34  ? 179.378 162.051 151.538 1.00 50.57  ? 366 SER A CA  1 
ATOM 1917 C C   . SER C 3 34  ? 179.540 162.032 150.024 1.00 50.57  ? 366 SER A C   1 
ATOM 1918 O O   . SER C 3 34  ? 180.518 162.571 149.492 1.00 50.57  ? 366 SER A O   1 
ATOM 1919 C CB  . SER C 3 34  ? 179.797 160.710 152.137 1.00 50.57  ? 366 SER A CB  1 
ATOM 1920 O OG  . SER C 3 34  ? 181.044 160.289 151.613 1.00 50.57  ? 366 SER A OG  1 
ATOM 1921 N N   . VAL C 3 35  ? 178.582 161.431 149.312 1.00 49.66  ? 367 VAL A N   1 
ATOM 1922 C CA  . VAL C 3 35  ? 178.658 161.385 147.855 1.00 49.66  ? 367 VAL A CA  1 
ATOM 1923 C C   . VAL C 3 35  ? 178.629 162.788 147.267 1.00 49.66  ? 367 VAL A C   1 
ATOM 1924 O O   . VAL C 3 35  ? 179.073 163.004 146.133 1.00 49.66  ? 367 VAL A O   1 
ATOM 1925 C CB  . VAL C 3 35  ? 177.524 160.510 147.286 1.00 49.66  ? 367 VAL A CB  1 
ATOM 1926 C CG1 . VAL C 3 35  ? 177.617 159.100 147.844 1.00 49.66  ? 367 VAL A CG1 1 
ATOM 1927 C CG2 . VAL C 3 35  ? 176.170 161.124 147.596 1.00 49.66  ? 367 VAL A CG2 1 
ATOM 1928 N N   . LEU C 3 36  ? 178.103 163.758 148.014 1.00 44.74  ? 368 LEU A N   1 
ATOM 1929 C CA  . LEU C 3 36  ? 178.185 165.156 147.613 1.00 44.74  ? 368 LEU A CA  1 
ATOM 1930 C C   . LEU C 3 36  ? 179.609 165.672 147.776 1.00 44.74  ? 368 LEU A C   1 
ATOM 1931 O O   . LEU C 3 36  ? 180.159 166.294 146.862 1.00 44.74  ? 368 LEU A O   1 
ATOM 1932 C CB  . LEU C 3 36  ? 177.215 166.009 148.431 1.00 44.74  ? 368 LEU A CB  1 
ATOM 1933 C CG  . LEU C 3 36  ? 175.743 166.028 148.023 1.00 44.74  ? 368 LEU A CG  1 
ATOM 1934 C CD1 . LEU C 3 36  ? 175.063 164.701 148.301 1.00 44.74  ? 368 LEU A CD1 1 
ATOM 1935 C CD2 . LEU C 3 36  ? 175.037 167.146 148.762 1.00 44.74  ? 368 LEU A CD2 1 
ATOM 1936 N N   . TYR C 3 37  ? 180.211 165.419 148.939 1.00 48.08  ? 369 TYR A N   1 
ATOM 1937 C CA  . TYR C 3 37  ? 181.570 165.889 149.189 1.00 48.08  ? 369 TYR A CA  1 
ATOM 1938 C C   . TYR C 3 37  ? 182.574 165.177 148.292 1.00 48.08  ? 369 TYR A C   1 
ATOM 1939 O O   . TYR C 3 37  ? 183.451 165.809 147.694 1.00 48.08  ? 369 TYR A O   1 
ATOM 1940 C CB  . TYR C 3 37  ? 181.928 165.690 150.662 1.00 48.08  ? 369 TYR A CB  1 
ATOM 1941 C CG  . TYR C 3 37  ? 183.072 166.557 151.140 1.00 48.08  ? 369 TYR A CG  1 
ATOM 1942 C CD1 . TYR C 3 37  ? 183.022 167.936 151.014 1.00 48.08  ? 369 TYR A CD1 1 
ATOM 1943 C CD2 . TYR C 3 37  ? 184.201 165.993 151.718 1.00 48.08  ? 369 TYR A CD2 1 
ATOM 1944 C CE1 . TYR C 3 37  ? 184.061 168.734 151.449 1.00 48.08  ? 369 TYR A CE1 1 
ATOM 1945 C CE2 . TYR C 3 37  ? 185.248 166.782 152.156 1.00 48.08  ? 369 TYR A CE2 1 
ATOM 1946 C CZ  . TYR C 3 37  ? 185.172 168.152 152.019 1.00 48.08  ? 369 TYR A CZ  1 
ATOM 1947 O OH  . TYR C 3 37  ? 186.210 168.943 152.453 1.00 48.08  ? 369 TYR A OH  1 
ATOM 1948 N N   . ASN C 3 38  ? 182.452 163.852 148.182 1.00 52.61  ? 370 ASN A N   1 
ATOM 1949 C CA  . ASN C 3 38  ? 183.427 163.079 147.422 1.00 52.61  ? 370 ASN A CA  1 
ATOM 1950 C C   . ASN C 3 38  ? 183.274 163.287 145.922 1.00 52.61  ? 370 ASN A C   1 
ATOM 1951 O O   . ASN C 3 38  ? 184.153 162.884 145.151 1.00 52.61  ? 370 ASN A O   1 
ATOM 1952 C CB  . ASN C 3 38  ? 183.298 161.596 147.767 1.00 52.61  ? 370 ASN A CB  1 
ATOM 1953 C CG  . ASN C 3 38  ? 183.621 161.309 149.219 1.00 52.61  ? 370 ASN A CG  1 
ATOM 1954 O OD1 . ASN C 3 38  ? 182.756 160.895 149.989 1.00 52.61  ? 370 ASN A OD1 1 
ATOM 1955 N ND2 . ASN C 3 38  ? 184.872 161.533 149.602 1.00 52.61  ? 370 ASN A ND2 1 
ATOM 1956 N N   . SER C 3 39  ? 182.175 163.901 145.489 1.00 49.72  ? 371 SER A N   1 
ATOM 1957 C CA  . SER C 3 39  ? 181.969 164.151 144.070 1.00 49.72  ? 371 SER A CA  1 
ATOM 1958 C C   . SER C 3 39  ? 183.003 165.139 143.546 1.00 49.72  ? 371 SER A C   1 
ATOM 1959 O O   . SER C 3 39  ? 183.283 166.163 144.175 1.00 49.72  ? 371 SER A O   1 
ATOM 1960 C CB  . SER C 3 39  ? 180.557 164.685 143.825 1.00 49.72  ? 371 SER A CB  1 
ATOM 1961 O OG  . SER C 3 39  ? 179.603 163.637 143.868 1.00 49.72  ? 371 SER A OG  1 
ATOM 1962 N N   . ALA C 3 40  ? 183.569 164.822 142.385 1.00 47.91  ? 372 ALA A N   1 
ATOM 1963 C CA  . ALA C 3 40  ? 184.570 165.662 141.745 1.00 47.91  ? 372 ALA A CA  1 
ATOM 1964 C C   . ALA C 3 40  ? 183.961 166.645 140.754 1.00 47.91  ? 372 ALA A C   1 
ATOM 1965 O O   . ALA C 3 40  ? 184.699 167.380 140.092 1.00 47.91  ? 372 ALA A O   1 
ATOM 1966 C CB  . ALA C 3 40  ? 185.617 164.794 141.043 1.00 47.91  ? 372 ALA A CB  1 
ATOM 1967 N N   . SER C 3 41  ? 182.635 166.670 140.635 1.00 42.05  ? 373 SER A N   1 
ATOM 1968 C CA  . SER C 3 41  ? 181.965 167.552 139.691 1.00 42.05  ? 373 SER A CA  1 
ATOM 1969 C C   . SER C 3 41  ? 181.597 168.905 140.285 1.00 42.05  ? 373 SER A C   1 
ATOM 1970 O O   . SER C 3 41  ? 181.138 169.780 139.545 1.00 42.05  ? 373 SER A O   1 
ATOM 1971 C CB  . SER C 3 41  ? 180.700 166.879 139.148 1.00 42.05  ? 373 SER A CB  1 
ATOM 1972 O OG  . SER C 3 41  ? 179.796 166.575 140.196 1.00 42.05  ? 373 SER A OG  1 
ATOM 1973 N N   . PHE C 3 42  ? 181.792 169.103 141.586 1.00 34.72  ? 374 PHE A N   1 
ATOM 1974 C CA  . PHE C 3 42  ? 181.390 170.345 142.235 1.00 34.72  ? 374 PHE A CA  1 
ATOM 1975 C C   . PHE C 3 42  ? 182.499 171.379 142.101 1.00 34.72  ? 374 PHE A C   1 
ATOM 1976 O O   . PHE C 3 42  ? 183.635 171.138 142.523 1.00 34.72  ? 374 PHE A O   1 
ATOM 1977 C CB  . PHE C 3 42  ? 181.067 170.107 143.709 1.00 34.72  ? 374 PHE A CB  1 
ATOM 1978 C CG  . PHE C 3 42  ? 179.776 169.379 143.945 1.00 34.72  ? 374 PHE A CG  1 
ATOM 1979 C CD1 . PHE C 3 42  ? 179.089 168.788 142.901 1.00 34.72  ? 374 PHE A CD1 1 
ATOM 1980 C CD2 . PHE C 3 42  ? 179.254 169.282 145.219 1.00 34.72  ? 374 PHE A CD2 1 
ATOM 1981 C CE1 . PHE C 3 42  ? 177.907 168.119 143.123 1.00 34.72  ? 374 PHE A CE1 1 
ATOM 1982 C CE2 . PHE C 3 42  ? 178.075 168.613 145.446 1.00 34.72  ? 374 PHE A CE2 1 
ATOM 1983 C CZ  . PHE C 3 42  ? 177.399 168.031 144.397 1.00 34.72  ? 374 PHE A CZ  1 
ATOM 1984 N N   . SER C 3 43  ? 182.172 172.528 141.510 1.00 30.72  ? 375 SER A N   1 
ATOM 1985 C CA  . SER C 3 43  ? 183.137 173.619 141.449 1.00 30.72  ? 375 SER A CA  1 
ATOM 1986 C C   . SER C 3 43  ? 183.360 174.233 142.824 1.00 30.72  ? 375 SER A C   1 
ATOM 1987 O O   . SER C 3 43  ? 184.492 174.584 143.177 1.00 30.72  ? 375 SER A O   1 
ATOM 1988 C CB  . SER C 3 43  ? 182.671 174.681 140.456 1.00 30.72  ? 375 SER A CB  1 
ATOM 1989 O OG  . SER C 3 43  ? 183.350 175.905 140.673 1.00 30.72  ? 375 SER A OG  1 
ATOM 1990 N N   . THR C 3 44  ? 182.296 174.376 143.611 1.00 27.88  ? 376 THR A N   1 
ATOM 1991 C CA  . THR C 3 44  ? 182.384 174.953 144.944 1.00 27.88  ? 376 THR A CA  1 
ATOM 1992 C C   . THR C 3 44  ? 181.529 174.138 145.901 1.00 27.88  ? 376 THR A C   1 
ATOM 1993 O O   . THR C 3 44  ? 180.542 173.518 145.501 1.00 27.88  ? 376 THR A O   1 
ATOM 1994 C CB  . THR C 3 44  ? 181.918 176.416 144.977 1.00 27.88  ? 376 THR A CB  1 
ATOM 1995 O OG1 . THR C 3 44  ? 180.544 176.491 144.582 1.00 27.88  ? 376 THR A OG1 1 
ATOM 1996 C CG2 . THR C 3 44  ? 182.759 177.279 144.047 1.00 27.88  ? 376 THR A CG2 1 
ATOM 1997 N N   . PHE C 3 45  ? 181.925 174.143 147.175 1.00 28.35  ? 377 PHE A N   1 
ATOM 1998 C CA  . PHE C 3 45  ? 181.164 173.453 148.215 1.00 28.35  ? 377 PHE A CA  1 
ATOM 1999 C C   . PHE C 3 45  ? 181.577 174.076 149.548 1.00 28.35  ? 377 PHE A C   1 
ATOM 2000 O O   . PHE C 3 45  ? 182.614 173.708 150.104 1.00 28.35  ? 377 PHE A O   1 
ATOM 2001 C CB  . PHE C 3 45  ? 181.436 171.959 148.195 1.00 28.35  ? 377 PHE A CB  1 
ATOM 2002 C CG  . PHE C 3 45  ? 180.635 171.182 149.197 1.00 28.35  ? 377 PHE A CG  1 
ATOM 2003 C CD1 . PHE C 3 45  ? 179.305 170.911 148.970 1.00 28.35  ? 377 PHE A CD1 1 
ATOM 2004 C CD2 . PHE C 3 45  ? 181.204 170.739 150.372 1.00 28.35  ? 377 PHE A CD2 1 
ATOM 2005 C CE1 . PHE C 3 45  ? 178.555 170.200 149.883 1.00 28.35  ? 377 PHE A CE1 1 
ATOM 2006 C CE2 . PHE C 3 45  ? 180.455 170.029 151.290 1.00 28.35  ? 377 PHE A CE2 1 
ATOM 2007 C CZ  . PHE C 3 45  ? 179.131 169.760 151.044 1.00 28.35  ? 377 PHE A CZ  1 
ATOM 2008 N N   . LYS C 3 46  ? 180.769 175.007 150.049 1.00 30.06  ? 378 LYS A N   1 
ATOM 2009 C CA  . LYS C 3 46  ? 181.091 175.714 151.286 1.00 30.06  ? 378 LYS A CA  1 
ATOM 2010 C C   . LYS C 3 46  ? 179.878 175.664 152.200 1.00 30.06  ? 378 LYS A C   1 
ATOM 2011 O O   . LYS C 3 46  ? 178.836 176.245 151.884 1.00 30.06  ? 378 LYS A O   1 
ATOM 2012 C CB  . LYS C 3 46  ? 181.507 177.159 151.014 1.00 30.06  ? 378 LYS A CB  1 
ATOM 2013 C CG  . LYS C 3 46  ? 180.789 177.812 149.849 1.00 30.06  ? 378 LYS A CG  1 
ATOM 2014 C CD  . LYS C 3 46  ? 181.590 178.980 149.294 1.00 30.06  ? 378 LYS A CD  1 
ATOM 2015 C CE  . LYS C 3 46  ? 180.862 179.658 148.142 1.00 30.06  ? 378 LYS A CE  1 
ATOM 2016 N NZ  . LYS C 3 46  ? 180.757 178.781 146.947 1.00 30.06  ? 378 LYS A NZ  1 
ATOM 2017 N N   . CYS C 3 47  ? 180.018 174.983 153.332 1.00 35.09  ? 379 CYS A N   1 
ATOM 2018 C CA  . CYS C 3 47  ? 178.947 174.851 154.309 1.00 35.09  ? 379 CYS A CA  1 
ATOM 2019 C C   . CYS C 3 47  ? 179.178 175.823 155.456 1.00 35.09  ? 379 CYS A C   1 
ATOM 2020 O O   . CYS C 3 47  ? 180.282 175.894 156.005 1.00 35.09  ? 379 CYS A O   1 
ATOM 2021 C CB  . CYS C 3 47  ? 178.867 173.420 154.840 1.00 35.09  ? 379 CYS A CB  1 
ATOM 2022 S SG  . CYS C 3 47  ? 178.496 172.182 153.586 1.00 35.09  ? 379 CYS A SG  1 
ATOM 2023 N N   . TYR C 3 48  ? 178.137 176.566 155.812 1.00 42.70  ? 380 TYR A N   1 
ATOM 2024 C CA  . TYR C 3 48  ? 178.188 177.537 156.896 1.00 42.70  ? 380 TYR A CA  1 
ATOM 2025 C C   . TYR C 3 48  ? 177.439 176.969 158.093 1.00 42.70  ? 380 TYR A C   1 
ATOM 2026 O O   . TYR C 3 48  ? 176.274 176.578 157.971 1.00 42.70  ? 380 TYR A O   1 
ATOM 2027 C CB  . TYR C 3 48  ? 177.587 178.877 156.470 1.00 42.70  ? 380 TYR A CB  1 
ATOM 2028 C CG  . TYR C 3 48  ? 178.065 179.382 155.125 1.00 42.70  ? 380 TYR A CG  1 
ATOM 2029 C CD1 . TYR C 3 48  ? 177.519 178.902 153.943 1.00 42.70  ? 380 TYR A CD1 1 
ATOM 2030 C CD2 . TYR C 3 48  ? 179.063 180.342 155.041 1.00 42.70  ? 380 TYR A CD2 1 
ATOM 2031 C CE1 . TYR C 3 48  ? 177.955 179.361 152.717 1.00 42.70  ? 380 TYR A CE1 1 
ATOM 2032 C CE2 . TYR C 3 48  ? 179.506 180.807 153.819 1.00 42.70  ? 380 TYR A CE2 1 
ATOM 2033 C CZ  . TYR C 3 48  ? 178.948 180.313 152.660 1.00 42.70  ? 380 TYR A CZ  1 
ATOM 2034 O OH  . TYR C 3 48  ? 179.384 180.773 151.439 1.00 42.70  ? 380 TYR A OH  1 
ATOM 2035 N N   . GLY C 3 49  ? 178.109 176.923 159.243 1.00 43.37  ? 381 GLY A N   1 
ATOM 2036 C CA  . GLY C 3 49  ? 177.514 176.426 160.462 1.00 43.37  ? 381 GLY A CA  1 
ATOM 2037 C C   . GLY C 3 49  ? 177.692 174.945 160.713 1.00 43.37  ? 381 GLY A C   1 
ATOM 2038 O O   . GLY C 3 49  ? 177.333 174.473 161.798 1.00 43.37  ? 381 GLY A O   1 
ATOM 2039 N N   . VAL C 3 50  ? 178.233 174.197 159.755 1.00 39.70  ? 382 VAL A N   1 
ATOM 2040 C CA  . VAL C 3 50  ? 178.463 172.766 159.926 1.00 39.70  ? 382 VAL A CA  1 
ATOM 2041 C C   . VAL C 3 50  ? 179.632 172.356 159.042 1.00 39.70  ? 382 VAL A C   1 
ATOM 2042 O O   . VAL C 3 50  ? 179.745 172.798 157.896 1.00 39.70  ? 382 VAL A O   1 
ATOM 2043 C CB  . VAL C 3 50  ? 177.193 171.948 159.605 1.00 39.70  ? 382 VAL A CB  1 
ATOM 2044 C CG1 . VAL C 3 50  ? 176.669 172.290 158.225 1.00 39.70  ? 382 VAL A CG1 1 
ATOM 2045 C CG2 . VAL C 3 50  ? 177.472 170.462 159.719 1.00 39.70  ? 382 VAL A CG2 1 
ATOM 2046 N N   . SER C 3 51  ? 180.508 171.520 159.583 1.00 40.43  ? 383 SER A N   1 
ATOM 2047 C CA  . SER C 3 51  ? 181.653 171.049 158.816 1.00 40.43  ? 383 SER A CA  1 
ATOM 2048 C C   . SER C 3 51  ? 181.190 170.075 157.740 1.00 40.43  ? 383 SER A C   1 
ATOM 2049 O O   . SER C 3 51  ? 180.330 169.227 158.007 1.00 40.43  ? 383 SER A O   1 
ATOM 2050 C CB  . SER C 3 51  ? 182.675 170.378 159.728 1.00 40.43  ? 383 SER A CB  1 
ATOM 2051 O OG  . SER C 3 51  ? 183.918 170.219 159.066 1.00 40.43  ? 383 SER A OG  1 
ATOM 2052 N N   . PRO C 3 52  ? 181.722 170.165 156.519 1.00 39.77  ? 384 PRO A N   1 
ATOM 2053 C CA  . PRO C 3 52  ? 181.288 169.246 155.455 1.00 39.77  ? 384 PRO A CA  1 
ATOM 2054 C C   . PRO C 3 52  ? 181.571 167.783 155.743 1.00 39.77  ? 384 PRO A C   1 
ATOM 2055 O O   . PRO C 3 52  ? 180.837 166.922 155.244 1.00 39.77  ? 384 PRO A O   1 
ATOM 2056 C CB  . PRO C 3 52  ? 182.075 169.729 154.230 1.00 39.77  ? 384 PRO A CB  1 
ATOM 2057 C CG  . PRO C 3 52  ? 182.537 171.110 154.572 1.00 39.77  ? 384 PRO A CG  1 
ATOM 2058 C CD  . PRO C 3 52  ? 182.737 171.119 156.050 1.00 39.77  ? 384 PRO A CD  1 
ATOM 2059 N N   . THR C 3 53  ? 182.607 167.470 156.522 1.00 40.32  ? 385 THR A N   1 
ATOM 2060 C CA  . THR C 3 53  ? 182.985 166.082 156.755 1.00 40.32  ? 385 THR A CA  1 
ATOM 2061 C C   . THR C 3 53  ? 182.162 165.408 157.845 1.00 40.32  ? 385 THR A C   1 
ATOM 2062 O O   . THR C 3 53  ? 182.206 164.179 157.955 1.00 40.32  ? 385 THR A O   1 
ATOM 2063 C CB  . THR C 3 53  ? 184.469 165.993 157.118 1.00 40.32  ? 385 THR A CB  1 
ATOM 2064 O OG1 . THR C 3 53  ? 184.710 166.727 158.325 1.00 40.32  ? 385 THR A OG1 1 
ATOM 2065 C CG2 . THR C 3 53  ? 185.325 166.568 156.003 1.00 40.32  ? 385 THR A CG2 1 
ATOM 2066 N N   . LYS C 3 54  ? 181.421 166.170 158.647 1.00 41.94  ? 386 LYS A N   1 
ATOM 2067 C CA  . LYS C 3 54  ? 180.592 165.611 159.706 1.00 41.94  ? 386 LYS A CA  1 
ATOM 2068 C C   . LYS C 3 54  ? 179.108 165.645 159.365 1.00 41.94  ? 386 LYS A C   1 
ATOM 2069 O O   . LYS C 3 54  ? 178.276 165.358 160.234 1.00 41.94  ? 386 LYS A O   1 
ATOM 2070 C CB  . LYS C 3 54  ? 180.850 166.347 161.022 1.00 41.94  ? 386 LYS A CB  1 
ATOM 2071 C CG  . LYS C 3 54  ? 180.341 167.779 161.054 1.00 41.94  ? 386 LYS A CG  1 
ATOM 2072 C CD  . LYS C 3 54  ? 180.540 168.401 162.432 1.00 41.94  ? 386 LYS A CD  1 
ATOM 2073 C CE  . LYS C 3 54  ? 179.523 169.500 162.705 1.00 41.94  ? 386 LYS A CE  1 
ATOM 2074 N NZ  . LYS C 3 54  ? 179.557 169.958 164.121 1.00 41.94  ? 386 LYS A NZ  1 
ATOM 2075 N N   . LEU C 3 55  ? 178.760 165.966 158.117 1.00 41.40  ? 387 LEU A N   1 
ATOM 2076 C CA  . LEU C 3 55  ? 177.356 166.105 157.742 1.00 41.40  ? 387 LEU A CA  1 
ATOM 2077 C C   . LEU C 3 55  ? 176.587 164.815 157.991 1.00 41.40  ? 387 LEU A C   1 
ATOM 2078 O O   . LEU C 3 55  ? 175.502 164.831 158.582 1.00 41.40  ? 387 LEU A O   1 
ATOM 2079 C CB  . LEU C 3 55  ? 177.244 166.522 156.276 1.00 41.40  ? 387 LEU A CB  1 
ATOM 2080 C CG  . LEU C 3 55  ? 177.605 167.972 155.961 1.00 41.40  ? 387 LEU A CG  1 
ATOM 2081 C CD1 . LEU C 3 55  ? 177.781 168.159 154.465 1.00 41.40  ? 387 LEU A CD1 1 
ATOM 2082 C CD2 . LEU C 3 55  ? 176.539 168.907 156.502 1.00 41.40  ? 387 LEU A CD2 1 
ATOM 2083 N N   . ASN C 3 56  ? 177.135 163.682 157.557 1.00 40.62  ? 388 ASN A N   1 
ATOM 2084 C CA  . ASN C 3 56  ? 176.480 162.415 157.848 1.00 40.62  ? 388 ASN A CA  1 
ATOM 2085 C C   . ASN C 3 56  ? 176.908 161.905 159.218 1.00 40.62  ? 388 ASN A C   1 
ATOM 2086 O O   . ASN C 3 56  ? 177.266 160.733 159.373 1.00 40.62  ? 388 ASN A O   1 
ATOM 2087 C CB  . ASN C 3 56  ? 176.789 161.383 156.762 1.00 40.62  ? 388 ASN A CB  1 
ATOM 2088 C CG  . ASN C 3 56  ? 178.262 161.322 156.418 1.00 40.62  ? 388 ASN A CG  1 
ATOM 2089 O OD1 . ASN C 3 56  ? 179.081 162.021 157.012 1.00 40.62  ? 388 ASN A OD1 1 
ATOM 2090 N ND2 . ASN C 3 56  ? 178.608 160.480 155.452 1.00 40.62  ? 388 ASN A ND2 1 
ATOM 2091 N N   . ASP C 3 57  ? 176.872 162.787 160.215 1.00 39.37  ? 389 ASP A N   1 
ATOM 2092 C CA  . ASP C 3 57  ? 176.999 162.391 161.614 1.00 39.37  ? 389 ASP A CA  1 
ATOM 2093 C C   . ASP C 3 57  ? 175.994 163.070 162.528 1.00 39.37  ? 389 ASP A C   1 
ATOM 2094 O O   . ASP C 3 57  ? 175.713 162.533 163.605 1.00 39.37  ? 389 ASP A O   1 
ATOM 2095 C CB  . ASP C 3 57  ? 178.413 162.676 162.133 1.00 39.37  ? 389 ASP A CB  1 
ATOM 2096 N N   . LEU C 3 58  ? 175.442 164.220 162.149 1.00 41.41  ? 390 LEU A N   1 
ATOM 2097 C CA  . LEU C 3 58  ? 174.426 164.905 162.926 1.00 41.41  ? 390 LEU A CA  1 
ATOM 2098 C C   . LEU C 3 58  ? 173.043 164.481 162.444 1.00 41.41  ? 390 LEU A C   1 
ATOM 2099 O O   . LEU C 3 58  ? 172.897 163.644 161.550 1.00 41.41  ? 390 LEU A O   1 
ATOM 2100 C CB  . LEU C 3 58  ? 174.598 166.419 162.818 1.00 41.41  ? 390 LEU A CB  1 
ATOM 2101 C CG  . LEU C 3 58  ? 176.025 166.958 162.809 1.00 41.41  ? 390 LEU A CG  1 
ATOM 2102 C CD1 . LEU C 3 58  ? 176.016 168.449 162.527 1.00 41.41  ? 390 LEU A CD1 1 
ATOM 2103 C CD2 . LEU C 3 58  ? 176.718 166.665 164.128 1.00 41.41  ? 390 LEU A CD2 1 
ATOM 2104 N N   . CYS C 3 59  ? 172.008 165.071 163.036 1.00 48.25  ? 391 CYS A N   1 
ATOM 2105 C CA  . CYS C 3 59  ? 170.643 164.754 162.651 1.00 48.25  ? 391 CYS A CA  1 
ATOM 2106 C C   . CYS C 3 59  ? 169.852 166.045 162.528 1.00 48.25  ? 391 CYS A C   1 
ATOM 2107 O O   . CYS C 3 59  ? 169.872 166.876 163.440 1.00 48.25  ? 391 CYS A O   1 
ATOM 2108 C CB  . CYS C 3 59  ? 169.993 163.806 163.662 1.00 48.25  ? 391 CYS A CB  1 
ATOM 2109 S SG  . CYS C 3 59  ? 168.324 163.292 163.233 1.00 48.25  ? 391 CYS A SG  1 
ATOM 2110 N N   . PHE C 3 60  ? 169.158 166.206 161.406 1.00 47.58  ? 392 PHE A N   1 
ATOM 2111 C CA  . PHE C 3 60  ? 168.505 167.458 161.053 1.00 47.58  ? 392 PHE A CA  1 
ATOM 2112 C C   . PHE C 3 60  ? 166.991 167.298 161.066 1.00 47.58  ? 392 PHE A C   1 
ATOM 2113 O O   . PHE C 3 60  ? 166.459 166.230 160.751 1.00 47.58  ? 392 PHE A O   1 
ATOM 2114 C CB  . PHE C 3 60  ? 168.952 167.938 159.669 1.00 47.58  ? 392 PHE A CB  1 
ATOM 2115 C CG  . PHE C 3 60  ? 170.438 168.057 159.525 1.00 47.58  ? 392 PHE A CG  1 
ATOM 2116 C CD1 . PHE C 3 60  ? 171.131 167.211 158.677 1.00 47.58  ? 392 PHE A CD1 1 
ATOM 2117 C CD2 . PHE C 3 60  ? 171.143 169.005 160.243 1.00 47.58  ? 392 PHE A CD2 1 
ATOM 2118 C CE1 . PHE C 3 60  ? 172.497 167.316 158.541 1.00 47.58  ? 392 PHE A CE1 1 
ATOM 2119 C CE2 . PHE C 3 60  ? 172.511 169.115 160.113 1.00 47.58  ? 392 PHE A CE2 1 
ATOM 2120 C CZ  . PHE C 3 60  ? 173.189 168.268 159.260 1.00 47.58  ? 392 PHE A CZ  1 
ATOM 2121 N N   . THR C 3 61  ? 166.301 168.377 161.440 1.00 53.43  ? 393 THR A N   1 
ATOM 2122 C CA  . THR C 3 61  ? 164.842 168.359 161.449 1.00 53.43  ? 393 THR A CA  1 
ATOM 2123 C C   . THR C 3 61  ? 164.287 168.206 160.039 1.00 53.43  ? 393 THR A C   1 
ATOM 2124 O O   . THR C 3 61  ? 163.430 167.351 159.784 1.00 53.43  ? 393 THR A O   1 
ATOM 2125 C CB  . THR C 3 61  ? 164.308 169.634 162.101 1.00 53.43  ? 393 THR A CB  1 
ATOM 2126 O OG1 . THR C 3 61  ? 164.783 169.718 163.450 1.00 53.43  ? 393 THR A OG1 1 
ATOM 2127 C CG2 . THR C 3 61  ? 162.787 169.635 162.101 1.00 53.43  ? 393 THR A CG2 1 
ATOM 2128 N N   . ASN C 3 62  ? 164.768 169.025 159.107 1.00 49.54  ? 394 ASN A N   1 
ATOM 2129 C CA  . ASN C 3 62  ? 164.314 168.969 157.725 1.00 49.54  ? 394 ASN A CA  1 
ATOM 2130 C C   . ASN C 3 62  ? 165.378 169.588 156.832 1.00 49.54  ? 394 ASN A C   1 
ATOM 2131 O O   . ASN C 3 62  ? 166.214 170.368 157.293 1.00 49.54  ? 394 ASN A O   1 
ATOM 2132 C CB  . ASN C 3 62  ? 162.972 169.687 157.545 1.00 49.54  ? 394 ASN A CB  1 
ATOM 2133 C CG  . ASN C 3 62  ? 162.971 171.083 158.140 1.00 49.54  ? 394 ASN A CG  1 
ATOM 2134 O OD1 . ASN C 3 62  ? 164.002 171.584 158.588 1.00 49.54  ? 394 ASN A OD1 1 
ATOM 2135 N ND2 . ASN C 3 62  ? 161.805 171.720 158.148 1.00 49.54  ? 394 ASN A ND2 1 
ATOM 2136 N N   . VAL C 3 63  ? 165.334 169.234 155.552 1.00 44.03  ? 395 VAL A N   1 
ATOM 2137 C CA  . VAL C 3 63  ? 166.301 169.724 154.578 1.00 44.03  ? 395 VAL A CA  1 
ATOM 2138 C C   . VAL C 3 63  ? 165.560 170.515 153.510 1.00 44.03  ? 395 VAL A C   1 
ATOM 2139 O O   . VAL C 3 63  ? 164.480 170.122 153.061 1.00 44.03  ? 395 VAL A O   1 
ATOM 2140 C CB  . VAL C 3 63  ? 167.107 168.560 153.963 1.00 44.03  ? 395 VAL A CB  1 
ATOM 2141 C CG1 . VAL C 3 63  ? 167.764 168.977 152.666 1.00 44.03  ? 395 VAL A CG1 1 
ATOM 2142 C CG2 . VAL C 3 63  ? 168.150 168.067 154.948 1.00 44.03  ? 395 VAL A CG2 1 
ATOM 2143 N N   . TYR C 3 64  ? 166.130 171.651 153.116 1.00 37.99  ? 396 TYR A N   1 
ATOM 2144 C CA  . TYR C 3 64  ? 165.544 172.478 152.067 1.00 37.99  ? 396 TYR A CA  1 
ATOM 2145 C C   . TYR C 3 64  ? 166.597 172.761 151.007 1.00 37.99  ? 396 TYR A C   1 
ATOM 2146 O O   . TYR C 3 64  ? 167.630 173.364 151.306 1.00 37.99  ? 396 TYR A O   1 
ATOM 2147 C CB  . TYR C 3 64  ? 164.989 173.777 152.650 1.00 37.99  ? 396 TYR A CB  1 
ATOM 2148 C CG  . TYR C 3 64  ? 163.704 173.581 153.419 1.00 37.99  ? 396 TYR A CG  1 
ATOM 2149 C CD1 . TYR C 3 64  ? 162.651 172.862 152.873 1.00 37.99  ? 396 TYR A CD1 1 
ATOM 2150 C CD2 . TYR C 3 64  ? 163.547 174.108 154.693 1.00 37.99  ? 396 TYR A CD2 1 
ATOM 2151 C CE1 . TYR C 3 64  ? 161.475 172.678 153.570 1.00 37.99  ? 396 TYR A CE1 1 
ATOM 2152 C CE2 . TYR C 3 64  ? 162.373 173.929 155.398 1.00 37.99  ? 396 TYR A CE2 1 
ATOM 2153 C CZ  . TYR C 3 64  ? 161.341 173.212 154.832 1.00 37.99  ? 396 TYR A CZ  1 
ATOM 2154 O OH  . TYR C 3 64  ? 160.170 173.029 155.529 1.00 37.99  ? 396 TYR A OH  1 
ATOM 2155 N N   . ALA C 3 65  ? 166.337 172.334 149.772 1.00 28.73  ? 397 ALA A N   1 
ATOM 2156 C CA  . ALA C 3 65  ? 167.318 172.445 148.693 1.00 28.73  ? 397 ALA A CA  1 
ATOM 2157 C C   . ALA C 3 65  ? 166.897 173.561 147.740 1.00 28.73  ? 397 ALA A C   1 
ATOM 2158 O O   . ALA C 3 65  ? 166.213 173.344 146.742 1.00 28.73  ? 397 ALA A O   1 
ATOM 2159 C CB  . ALA C 3 65  ? 167.468 171.111 147.971 1.00 28.73  ? 397 ALA A CB  1 
ATOM 2160 N N   . ASP C 3 66  ? 167.336 174.777 148.054 1.00 28.01  ? 398 ASP A N   1 
ATOM 2161 C CA  . ASP C 3 66  ? 167.067 175.942 147.214 1.00 28.01  ? 398 ASP A CA  1 
ATOM 2162 C C   . ASP C 3 66  ? 167.897 175.833 145.944 1.00 28.01  ? 398 ASP A C   1 
ATOM 2163 O O   . ASP C 3 66  ? 169.092 176.121 145.945 1.00 28.01  ? 398 ASP A O   1 
ATOM 2164 C CB  . ASP C 3 66  ? 167.400 177.224 147.966 1.00 28.01  ? 398 ASP A CB  1 
ATOM 2165 C CG  . ASP C 3 66  ? 166.680 177.329 149.289 1.00 28.01  ? 398 ASP A CG  1 
ATOM 2166 O OD1 . ASP C 3 66  ? 167.141 176.710 150.270 1.00 28.01  ? 398 ASP A OD1 1 
ATOM 2167 O OD2 . ASP C 3 66  ? 165.663 178.045 149.356 1.00 28.01  ? 398 ASP A OD2 1 
ATOM 2168 N N   . SER C 3 67  ? 167.274 175.419 144.852 1.00 26.64  ? 399 SER A N   1 
ATOM 2169 C CA  . SER C 3 67  ? 167.987 175.251 143.596 1.00 26.64  ? 399 SER A CA  1 
ATOM 2170 C C   . SER C 3 67  ? 167.660 176.383 142.632 1.00 26.64  ? 399 SER A C   1 
ATOM 2171 O O   . SER C 3 67  ? 166.496 176.747 142.439 1.00 26.64  ? 399 SER A O   1 
ATOM 2172 C CB  . SER C 3 67  ? 167.647 173.905 142.957 1.00 26.64  ? 399 SER A CB  1 
ATOM 2173 O OG  . SER C 3 67  ? 166.261 173.633 143.039 1.00 26.64  ? 399 SER A OG  1 
ATOM 2174 N N   . PHE C 3 68  ? 168.707 176.942 142.027 1.00 25.77  ? 400 PHE A N   1 
ATOM 2175 C CA  . PHE C 3 68  ? 168.556 178.028 141.066 1.00 25.77  ? 400 PHE A CA  1 
ATOM 2176 C C   . PHE C 3 68  ? 169.826 178.104 140.229 1.00 25.77  ? 400 PHE A C   1 
ATOM 2177 O O   . PHE C 3 68  ? 170.729 177.277 140.363 1.00 25.77  ? 400 PHE A O   1 
ATOM 2178 C CB  . PHE C 3 68  ? 168.257 179.352 141.770 1.00 25.77  ? 400 PHE A CB  1 
ATOM 2179 C CG  . PHE C 3 68  ? 169.246 179.706 142.835 1.00 25.77  ? 400 PHE A CG  1 
ATOM 2180 C CD1 . PHE C 3 68  ? 169.099 179.225 144.121 1.00 25.77  ? 400 PHE A CD1 1 
ATOM 2181 C CD2 . PHE C 3 68  ? 170.310 180.539 142.556 1.00 25.77  ? 400 PHE A CD2 1 
ATOM 2182 C CE1 . PHE C 3 68  ? 170.008 179.548 145.099 1.00 25.77  ? 400 PHE A CE1 1 
ATOM 2183 C CE2 . PHE C 3 68  ? 171.217 180.873 143.536 1.00 25.77  ? 400 PHE A CE2 1 
ATOM 2184 C CZ  . PHE C 3 68  ? 171.065 180.378 144.810 1.00 25.77  ? 400 PHE A CZ  1 
ATOM 2185 N N   . VAL C 3 69  ? 169.886 179.101 139.351 1.00 26.74  ? 401 VAL A N   1 
ATOM 2186 C CA  . VAL C 3 69  ? 171.005 179.272 138.432 1.00 26.74  ? 401 VAL A CA  1 
ATOM 2187 C C   . VAL C 3 69  ? 171.399 180.741 138.413 1.00 26.74  ? 401 VAL A C   1 
ATOM 2188 O O   . VAL C 3 69  ? 170.540 181.615 138.245 1.00 26.74  ? 401 VAL A O   1 
ATOM 2189 C CB  . VAL C 3 69  ? 170.661 178.791 137.014 1.00 26.74  ? 401 VAL A CB  1 
ATOM 2190 C CG1 . VAL C 3 69  ? 171.651 179.341 136.009 1.00 26.74  ? 401 VAL A CG1 1 
ATOM 2191 C CG2 . VAL C 3 69  ? 170.641 177.283 136.963 1.00 26.74  ? 401 VAL A CG2 1 
ATOM 2192 N N   . ILE C 3 70  ? 172.691 181.012 138.573 1.00 34.25  ? 402 ILE A N   1 
ATOM 2193 C CA  . ILE C 3 70  ? 173.244 182.350 138.478 1.00 34.25  ? 402 ILE A CA  1 
ATOM 2194 C C   . ILE C 3 70  ? 174.514 182.287 137.635 1.00 34.25  ? 402 ILE A C   1 
ATOM 2195 O O   . ILE C 3 70  ? 174.894 181.234 137.129 1.00 34.25  ? 402 ILE A O   1 
ATOM 2196 C CB  . ILE C 3 70  ? 173.530 182.963 139.862 1.00 34.25  ? 402 ILE A CB  1 
ATOM 2197 C CG1 . ILE C 3 70  ? 174.255 181.955 140.745 1.00 34.25  ? 402 ILE A CG1 1 
ATOM 2198 C CG2 . ILE C 3 70  ? 172.244 183.403 140.525 1.00 34.25  ? 402 ILE A CG2 1 
ATOM 2199 C CD1 . ILE C 3 70  ? 174.556 182.478 142.116 1.00 34.25  ? 402 ILE A CD1 1 
ATOM 2200 N N   . ARG C 3 71  ? 175.163 183.435 137.481 1.00 44.10  ? 403 ARG A N   1 
ATOM 2201 C CA  . ARG C 3 71  ? 176.411 183.508 136.739 1.00 44.10  ? 403 ARG A CA  1 
ATOM 2202 C C   . ARG C 3 71  ? 177.599 183.364 137.683 1.00 44.10  ? 403 ARG A C   1 
ATOM 2203 O O   . ARG C 3 71  ? 177.474 183.486 138.903 1.00 44.10  ? 403 ARG A O   1 
ATOM 2204 C CB  . ARG C 3 71  ? 176.506 184.822 135.964 1.00 44.10  ? 403 ARG A CB  1 
ATOM 2205 C CG  . ARG C 3 71  ? 176.542 186.064 136.836 1.00 44.10  ? 403 ARG A CG  1 
ATOM 2206 C CD  . ARG C 3 71  ? 177.165 187.242 136.100 1.00 44.10  ? 403 ARG A CD  1 
ATOM 2207 N NE  . ARG C 3 71  ? 176.274 187.802 135.091 1.00 44.10  ? 403 ARG A NE  1 
ATOM 2208 C CZ  . ARG C 3 71  ? 176.339 187.526 133.796 1.00 44.10  ? 403 ARG A CZ  1 
ATOM 2209 N NH1 . ARG C 3 71  ? 177.241 186.690 133.311 1.00 44.10  ? 403 ARG A NH1 1 
ATOM 2210 N NH2 . ARG C 3 71  ? 175.476 188.105 132.965 1.00 44.10  ? 403 ARG A NH2 1 
ATOM 2211 N N   . GLY C 3 72  ? 178.768 183.102 137.093 1.00 44.47  ? 404 GLY A N   1 
ATOM 2212 C CA  . GLY C 3 72  ? 179.952 182.842 137.897 1.00 44.47  ? 404 GLY A CA  1 
ATOM 2213 C C   . GLY C 3 72  ? 180.316 183.995 138.811 1.00 44.47  ? 404 GLY A C   1 
ATOM 2214 O O   . GLY C 3 72  ? 180.722 183.787 139.957 1.00 44.47  ? 404 GLY A O   1 
ATOM 2215 N N   . ASP C 3 73  ? 180.178 185.227 138.319 1.00 49.23  ? 405 ASP A N   1 
ATOM 2216 C CA  . ASP C 3 73  ? 180.422 186.391 139.162 1.00 49.23  ? 405 ASP A CA  1 
ATOM 2217 C C   . ASP C 3 73  ? 179.411 186.502 140.294 1.00 49.23  ? 405 ASP A C   1 
ATOM 2218 O O   . ASP C 3 73  ? 179.673 187.202 141.277 1.00 49.23  ? 405 ASP A O   1 
ATOM 2219 C CB  . ASP C 3 73  ? 180.395 187.668 138.322 1.00 49.23  ? 405 ASP A CB  1 
ATOM 2220 C CG  . ASP C 3 73  ? 181.521 187.727 137.313 1.00 49.23  ? 405 ASP A CG  1 
ATOM 2221 O OD1 . ASP C 3 73  ? 182.607 187.183 137.599 1.00 49.23  ? 405 ASP A OD1 1 
ATOM 2222 O OD2 . ASP C 3 73  ? 181.318 188.314 136.229 1.00 49.23  ? 405 ASP A OD2 1 
ATOM 2223 N N   . GLU C 3 74  ? 178.263 185.835 140.177 1.00 48.08  ? 406 GLU A N   1 
ATOM 2224 C CA  . GLU C 3 74  ? 177.202 185.942 141.166 1.00 48.08  ? 406 GLU A CA  1 
ATOM 2225 C C   . GLU C 3 74  ? 177.236 184.843 142.219 1.00 48.08  ? 406 GLU A C   1 
ATOM 2226 O O   . GLU C 3 74  ? 176.502 184.937 143.207 1.00 48.08  ? 406 GLU A O   1 
ATOM 2227 C CB  . GLU C 3 74  ? 175.835 185.934 140.471 1.00 48.08  ? 406 GLU A CB  1 
ATOM 2228 N N   . VAL C 3 75  ? 178.059 183.808 142.040 1.00 43.42  ? 407 VAL A N   1 
ATOM 2229 C CA  . VAL C 3 75  ? 178.121 182.745 143.037 1.00 43.42  ? 407 VAL A CA  1 
ATOM 2230 C C   . VAL C 3 75  ? 178.773 183.242 144.318 1.00 43.42  ? 407 VAL A C   1 
ATOM 2231 O O   . VAL C 3 75  ? 178.450 182.764 145.413 1.00 43.42  ? 407 VAL A O   1 
ATOM 2232 C CB  . VAL C 3 75  ? 178.857 181.519 142.471 1.00 43.42  ? 407 VAL A CB  1 
ATOM 2233 C CG1 . VAL C 3 75  ? 178.675 180.324 143.385 1.00 43.42  ? 407 VAL A CG1 1 
ATOM 2234 C CG2 . VAL C 3 75  ? 178.345 181.203 141.088 1.00 43.42  ? 407 VAL A CG2 1 
ATOM 2235 N N   . ARG C 3 76  ? 179.692 184.203 144.212 1.00 53.13  ? 408 ARG A N   1 
ATOM 2236 C CA  . ARG C 3 76  ? 180.413 184.668 145.390 1.00 53.13  ? 408 ARG A CA  1 
ATOM 2237 C C   . ARG C 3 76  ? 179.484 185.314 146.408 1.00 53.13  ? 408 ARG A C   1 
ATOM 2238 O O   . ARG C 3 76  ? 179.777 185.295 147.608 1.00 53.13  ? 408 ARG A O   1 
ATOM 2239 C CB  . ARG C 3 76  ? 181.507 185.654 144.982 1.00 53.13  ? 408 ARG A CB  1 
ATOM 2240 C CG  . ARG C 3 76  ? 180.990 186.834 144.186 1.00 53.13  ? 408 ARG A CG  1 
ATOM 2241 C CD  . ARG C 3 76  ? 182.057 187.893 143.986 1.00 53.13  ? 408 ARG A CD  1 
ATOM 2242 N NE  . ARG C 3 76  ? 181.579 188.977 143.136 1.00 53.13  ? 408 ARG A NE  1 
ATOM 2243 C CZ  . ARG C 3 76  ? 180.760 189.938 143.540 1.00 53.13  ? 408 ARG A CZ  1 
ATOM 2244 N NH1 . ARG C 3 76  ? 180.309 189.986 144.783 1.00 53.13  ? 408 ARG A NH1 1 
ATOM 2245 N NH2 . ARG C 3 76  ? 180.384 190.876 142.675 1.00 53.13  ? 408 ARG A NH2 1 
ATOM 2246 N N   . GLN C 3 77  ? 178.364 185.881 145.963 1.00 53.36  ? 409 GLN A N   1 
ATOM 2247 C CA  . GLN C 3 77  ? 177.446 186.566 146.862 1.00 53.36  ? 409 GLN A CA  1 
ATOM 2248 C C   . GLN C 3 77  ? 176.336 185.663 147.381 1.00 53.36  ? 409 GLN A C   1 
ATOM 2249 O O   . GLN C 3 77  ? 175.402 186.158 148.021 1.00 53.36  ? 409 GLN A O   1 
ATOM 2250 C CB  . GLN C 3 77  ? 176.846 187.800 146.182 1.00 53.36  ? 409 GLN A CB  1 
ATOM 2251 C CG  . GLN C 3 77  ? 176.049 187.524 144.926 1.00 53.36  ? 409 GLN A CG  1 
ATOM 2252 C CD  . GLN C 3 77  ? 175.994 188.729 144.009 1.00 53.36  ? 409 GLN A CD  1 
ATOM 2253 O OE1 . GLN C 3 77  ? 175.313 189.712 144.298 1.00 53.36  ? 409 GLN A OE1 1 
ATOM 2254 N NE2 . GLN C 3 77  ? 176.721 188.664 142.902 1.00 53.36  ? 409 GLN A NE2 1 
ATOM 2255 N N   . ILE C 3 78  ? 176.408 184.362 147.122 1.00 45.35  ? 410 ILE A N   1 
ATOM 2256 C CA  . ILE C 3 78  ? 175.513 183.397 147.781 1.00 45.35  ? 410 ILE A CA  1 
ATOM 2257 C C   . ILE C 3 78  ? 176.212 183.013 149.079 1.00 45.35  ? 410 ILE A C   1 
ATOM 2258 O O   . ILE C 3 78  ? 176.923 182.010 149.183 1.00 45.35  ? 410 ILE A O   1 
ATOM 2259 C CB  . ILE C 3 78  ? 175.193 182.196 146.888 1.00 45.35  ? 410 ILE A CB  1 
ATOM 2260 C CG1 . ILE C 3 78  ? 174.397 182.649 145.668 1.00 45.35  ? 410 ILE A CG1 1 
ATOM 2261 C CG2 . ILE C 3 78  ? 174.382 181.162 147.645 1.00 45.35  ? 410 ILE A CG2 1 
ATOM 2262 C CD1 . ILE C 3 78  ? 173.145 183.410 146.016 1.00 45.35  ? 410 ILE A CD1 1 
ATOM 2263 N N   . ALA C 3 79  ? 176.017 183.850 150.095 1.00 51.67  ? 411 ALA A N   1 
ATOM 2264 C CA  . ALA C 3 79  ? 176.663 183.699 151.391 1.00 51.67  ? 411 ALA A CA  1 
ATOM 2265 C C   . ALA C 3 79  ? 175.988 184.622 152.397 1.00 51.67  ? 411 ALA A C   1 
ATOM 2266 O O   . ALA C 3 79  ? 175.449 185.667 152.013 1.00 51.67  ? 411 ALA A O   1 
ATOM 2267 C CB  . ALA C 3 79  ? 178.158 184.010 151.294 1.00 51.67  ? 411 ALA A CB  1 
ATOM 2268 N N   . PRO C 3 80  ? 175.984 184.270 153.681 1.00 55.48  ? 412 PRO A N   1 
ATOM 2269 C CA  . PRO C 3 80  ? 175.350 185.139 154.679 1.00 55.48  ? 412 PRO A CA  1 
ATOM 2270 C C   . PRO C 3 80  ? 176.016 186.506 154.744 1.00 55.48  ? 412 PRO A C   1 
ATOM 2271 O O   . PRO C 3 80  ? 177.238 186.631 154.638 1.00 55.48  ? 412 PRO A O   1 
ATOM 2272 C CB  . PRO C 3 80  ? 175.533 184.366 155.990 1.00 55.48  ? 412 PRO A CB  1 
ATOM 2273 C CG  . PRO C 3 80  ? 175.774 182.956 155.578 1.00 55.48  ? 412 PRO A CG  1 
ATOM 2274 C CD  . PRO C 3 80  ? 176.488 183.020 154.270 1.00 55.48  ? 412 PRO A CD  1 
ATOM 2275 N N   . GLY C 3 81  ? 175.194 187.538 154.920 1.00 60.62  ? 413 GLY A N   1 
ATOM 2276 C CA  . GLY C 3 81  ? 175.693 188.881 155.136 1.00 60.62  ? 413 GLY A CA  1 
ATOM 2277 C C   . GLY C 3 81  ? 176.110 189.622 153.883 1.00 60.62  ? 413 GLY A C   1 
ATOM 2278 O O   . GLY C 3 81  ? 175.890 190.832 153.772 1.00 60.62  ? 413 GLY A O   1 
ATOM 2279 N N   . GLN C 3 82  ? 176.714 188.913 152.934 1.00 59.83  ? 414 GLN A N   1 
ATOM 2280 C CA  . GLN C 3 82  ? 177.216 189.555 151.728 1.00 59.83  ? 414 GLN A CA  1 
ATOM 2281 C C   . GLN C 3 82  ? 176.064 190.073 150.876 1.00 59.83  ? 414 GLN A C   1 
ATOM 2282 O O   . GLN C 3 82  ? 175.033 189.411 150.726 1.00 59.83  ? 414 GLN A O   1 
ATOM 2283 C CB  . GLN C 3 82  ? 178.077 188.575 150.931 1.00 59.83  ? 414 GLN A CB  1 
ATOM 2284 C CG  . GLN C 3 82  ? 178.517 189.083 149.571 1.00 59.83  ? 414 GLN A CG  1 
ATOM 2285 C CD  . GLN C 3 82  ? 179.662 188.275 149.001 1.00 59.83  ? 414 GLN A CD  1 
ATOM 2286 O OE1 . GLN C 3 82  ? 180.019 187.225 149.534 1.00 59.83  ? 414 GLN A OE1 1 
ATOM 2287 N NE2 . GLN C 3 82  ? 180.247 188.761 147.912 1.00 59.83  ? 414 GLN A NE2 1 
ATOM 2288 N N   . THR C 3 83  ? 176.245 191.266 150.317 1.00 60.33  ? 415 THR A N   1 
ATOM 2289 C CA  . THR C 3 83  ? 175.223 191.943 149.535 1.00 60.33  ? 415 THR A CA  1 
ATOM 2290 C C   . THR C 3 83  ? 175.703 192.141 148.102 1.00 60.33  ? 415 THR A C   1 
ATOM 2291 O O   . THR C 3 83  ? 176.883 191.975 147.784 1.00 60.33  ? 415 THR A O   1 
ATOM 2292 C CB  . THR C 3 83  ? 174.853 193.296 150.159 1.00 60.33  ? 415 THR A CB  1 
ATOM 2293 N N   . GLY C 3 84  ? 174.760 192.501 147.237 1.00 53.33  ? 416 GLY A N   1 
ATOM 2294 C CA  . GLY C 3 84  ? 175.038 192.694 145.828 1.00 53.33  ? 416 GLY A CA  1 
ATOM 2295 C C   . GLY C 3 84  ? 173.768 192.816 145.014 1.00 53.33  ? 416 GLY A C   1 
ATOM 2296 O O   . GLY C 3 84  ? 172.876 193.595 145.361 1.00 53.33  ? 416 GLY A O   1 
ATOM 2297 N N   . LYS C 3 85  ? 173.672 192.058 143.925 1.00 49.40  ? 417 LYS A N   1 
ATOM 2298 C CA  . LYS C 3 85  ? 172.455 192.008 143.125 1.00 49.40  ? 417 LYS A CA  1 
ATOM 2299 C C   . LYS C 3 85  ? 171.625 190.766 143.421 1.00 49.40  ? 417 LYS A C   1 
ATOM 2300 O O   . LYS C 3 85  ? 170.437 190.873 143.738 1.00 49.40  ? 417 LYS A O   1 
ATOM 2301 C CB  . LYS C 3 85  ? 172.800 192.063 141.632 1.00 49.40  ? 417 LYS A CB  1 
ATOM 2302 N N   . ILE C 3 86  ? 172.237 189.584 143.325 1.00 48.09  ? 418 ILE A N   1 
ATOM 2303 C CA  . ILE C 3 86  ? 171.529 188.346 143.639 1.00 48.09  ? 418 ILE A CA  1 
ATOM 2304 C C   . ILE C 3 86  ? 171.151 188.310 145.113 1.00 48.09  ? 418 ILE A C   1 
ATOM 2305 O O   . ILE C 3 86  ? 170.037 187.916 145.477 1.00 48.09  ? 418 ILE A O   1 
ATOM 2306 C CB  . ILE C 3 86  ? 172.385 187.129 143.244 1.00 48.09  ? 418 ILE A CB  1 
ATOM 2307 C CG1 . ILE C 3 86  ? 172.708 187.159 141.750 1.00 48.09  ? 418 ILE A CG1 1 
ATOM 2308 C CG2 . ILE C 3 86  ? 171.672 185.840 143.597 1.00 48.09  ? 418 ILE A CG2 1 
ATOM 2309 C CD1 . ILE C 3 86  ? 171.525 187.465 140.870 1.00 48.09  ? 418 ILE A CD1 1 
ATOM 2310 N N   . ALA C 3 87  ? 172.066 188.727 145.983 1.00 51.45  ? 419 ALA A N   1 
ATOM 2311 C CA  . ALA C 3 87  ? 171.851 188.687 147.422 1.00 51.45  ? 419 ALA A CA  1 
ATOM 2312 C C   . ALA C 3 87  ? 170.978 189.826 147.929 1.00 51.45  ? 419 ALA A C   1 
ATOM 2313 O O   . ALA C 3 87  ? 170.809 189.956 149.145 1.00 51.45  ? 419 ALA A O   1 
ATOM 2314 C CB  . ALA C 3 87  ? 173.194 188.702 148.155 1.00 51.45  ? 419 ALA A CB  1 
ATOM 2315 N N   . ASP C 3 88  ? 170.430 190.654 147.043 1.00 52.49  ? 420 ASP A N   1 
ATOM 2316 C CA  . ASP C 3 88  ? 169.550 191.741 147.454 1.00 52.49  ? 420 ASP A CA  1 
ATOM 2317 C C   . ASP C 3 88  ? 168.227 191.797 146.711 1.00 52.49  ? 420 ASP A C   1 
ATOM 2318 O O   . ASP C 3 88  ? 167.257 192.317 147.273 1.00 52.49  ? 420 ASP A O   1 
ATOM 2319 C CB  . ASP C 3 88  ? 170.254 193.097 147.299 1.00 52.49  ? 420 ASP A CB  1 
ATOM 2320 C CG  . ASP C 3 88  ? 171.336 193.314 148.338 1.00 52.49  ? 420 ASP A CG  1 
ATOM 2321 O OD1 . ASP C 3 88  ? 171.205 192.770 149.454 1.00 52.49  ? 420 ASP A OD1 1 
ATOM 2322 O OD2 . ASP C 3 88  ? 172.313 194.033 148.044 1.00 52.49  ? 420 ASP A OD2 1 
ATOM 2323 N N   . TYR C 3 89  ? 168.141 191.289 145.483 1.00 53.07  ? 421 TYR A N   1 
ATOM 2324 C CA  . TYR C 3 89  ? 166.891 191.355 144.743 1.00 53.07  ? 421 TYR A CA  1 
ATOM 2325 C C   . TYR C 3 89  ? 166.376 190.002 144.276 1.00 53.07  ? 421 TYR A C   1 
ATOM 2326 O O   . TYR C 3 89  ? 165.246 189.936 143.782 1.00 53.07  ? 421 TYR A O   1 
ATOM 2327 C CB  . TYR C 3 89  ? 167.035 192.286 143.528 1.00 53.07  ? 421 TYR A CB  1 
ATOM 2328 C CG  . TYR C 3 89  ? 167.517 193.677 143.874 1.00 53.07  ? 421 TYR A CG  1 
ATOM 2329 C CD1 . TYR C 3 89  ? 166.952 194.387 144.924 1.00 53.07  ? 421 TYR A CD1 1 
ATOM 2330 C CD2 . TYR C 3 89  ? 168.532 194.282 143.146 1.00 53.07  ? 421 TYR A CD2 1 
ATOM 2331 C CE1 . TYR C 3 89  ? 167.388 195.657 145.243 1.00 53.07  ? 421 TYR A CE1 1 
ATOM 2332 C CE2 . TYR C 3 89  ? 168.974 195.552 143.457 1.00 53.07  ? 421 TYR A CE2 1 
ATOM 2333 C CZ  . TYR C 3 89  ? 168.398 196.235 144.506 1.00 53.07  ? 421 TYR A CZ  1 
ATOM 2334 O OH  . TYR C 3 89  ? 168.835 197.501 144.821 1.00 53.07  ? 421 TYR A OH  1 
ATOM 2335 N N   . ASN C 3 90  ? 167.151 188.928 144.410 1.00 45.20  ? 422 ASN A N   1 
ATOM 2336 C CA  . ASN C 3 90  ? 166.682 187.620 143.971 1.00 45.20  ? 422 ASN A CA  1 
ATOM 2337 C C   . ASN C 3 90  ? 166.658 186.603 145.106 1.00 45.20  ? 422 ASN A C   1 
ATOM 2338 O O   . ASN C 3 90  ? 165.661 185.897 145.290 1.00 45.20  ? 422 ASN A O   1 
ATOM 2339 C CB  . ASN C 3 90  ? 167.553 187.115 142.823 1.00 45.20  ? 422 ASN A CB  1 
ATOM 2340 C CG  . ASN C 3 90  ? 167.553 188.060 141.643 1.00 45.20  ? 422 ASN A CG  1 
ATOM 2341 O OD1 . ASN C 3 90  ? 166.599 188.105 140.869 1.00 45.20  ? 422 ASN A OD1 1 
ATOM 2342 N ND2 . ASN C 3 90  ? 168.620 188.835 141.508 1.00 45.20  ? 422 ASN A ND2 1 
ATOM 2343 N N   . TYR C 3 91  ? 167.747 186.516 145.874 1.00 43.43  ? 423 TYR A N   1 
ATOM 2344 C CA  . TYR C 3 91  ? 167.848 185.508 146.929 1.00 43.43  ? 423 TYR A CA  1 
ATOM 2345 C C   . TYR C 3 91  ? 168.855 186.010 147.961 1.00 43.43  ? 423 TYR A C   1 
ATOM 2346 O O   . TYR C 3 91  ? 170.063 185.965 147.716 1.00 43.43  ? 423 TYR A O   1 
ATOM 2347 C CB  . TYR C 3 91  ? 168.270 184.166 146.359 1.00 43.43  ? 423 TYR A CB  1 
ATOM 2348 C CG  . TYR C 3 91  ? 168.312 183.044 147.372 1.00 43.43  ? 423 TYR A CG  1 
ATOM 2349 C CD1 . TYR C 3 91  ? 169.057 181.903 147.131 1.00 43.43  ? 423 TYR A CD1 1 
ATOM 2350 C CD2 . TYR C 3 91  ? 167.578 183.108 148.548 1.00 43.43  ? 423 TYR A CD2 1 
ATOM 2351 C CE1 . TYR C 3 91  ? 169.096 180.869 148.040 1.00 43.43  ? 423 TYR A CE1 1 
ATOM 2352 C CE2 . TYR C 3 91  ? 167.609 182.075 149.465 1.00 43.43  ? 423 TYR A CE2 1 
ATOM 2353 C CZ  . TYR C 3 91  ? 168.370 180.958 149.202 1.00 43.43  ? 423 TYR A CZ  1 
ATOM 2354 O OH  . TYR C 3 91  ? 168.409 179.922 150.104 1.00 43.43  ? 423 TYR A OH  1 
ATOM 2355 N N   . LYS C 3 92  ? 168.356 186.467 149.105 1.00 49.12  ? 424 LYS A N   1 
ATOM 2356 C CA  . LYS C 3 92  ? 169.210 186.914 150.196 1.00 49.12  ? 424 LYS A CA  1 
ATOM 2357 C C   . LYS C 3 92  ? 169.297 185.811 151.242 1.00 49.12  ? 424 LYS A C   1 
ATOM 2358 O O   . LYS C 3 92  ? 168.277 185.405 151.809 1.00 49.12  ? 424 LYS A O   1 
ATOM 2359 C CB  . LYS C 3 92  ? 168.683 188.205 150.820 1.00 49.12  ? 424 LYS A CB  1 
ATOM 2360 C CG  . LYS C 3 92  ? 169.573 188.746 151.926 1.00 49.12  ? 424 LYS A CG  1 
ATOM 2361 C CD  . LYS C 3 92  ? 169.080 190.083 152.442 1.00 49.12  ? 424 LYS A CD  1 
ATOM 2362 C CE  . LYS C 3 92  ? 169.893 190.533 153.642 1.00 49.12  ? 424 LYS A CE  1 
ATOM 2363 N NZ  . LYS C 3 92  ? 171.307 190.821 153.274 1.00 49.12  ? 424 LYS A NZ  1 
ATOM 2364 N N   . LEU C 3 93  ? 170.507 185.327 151.487 1.00 49.77  ? 425 LEU A N   1 
ATOM 2365 C CA  . LEU C 3 93  ? 170.721 184.302 152.501 1.00 49.77  ? 425 LEU A CA  1 
ATOM 2366 C C   . LEU C 3 93  ? 170.728 184.940 153.886 1.00 49.77  ? 425 LEU A C   1 
ATOM 2367 O O   . LEU C 3 93  ? 171.270 186.037 154.052 1.00 49.77  ? 425 LEU A O   1 
ATOM 2368 C CB  . LEU C 3 93  ? 172.032 183.568 152.250 1.00 49.77  ? 425 LEU A CB  1 
ATOM 2369 C CG  . LEU C 3 93  ? 171.967 182.429 151.232 1.00 49.77  ? 425 LEU A CG  1 
ATOM 2370 C CD1 . LEU C 3 93  ? 173.291 181.696 151.157 1.00 49.77  ? 425 LEU A CD1 1 
ATOM 2371 C CD2 . LEU C 3 93  ? 170.850 181.471 151.589 1.00 49.77  ? 425 LEU A CD2 1 
ATOM 2372 N N   . PRO C 3 94  ? 170.141 184.296 154.893 1.00 51.62  ? 426 PRO A N   1 
ATOM 2373 C CA  . PRO C 3 94  ? 170.093 184.899 156.228 1.00 51.62  ? 426 PRO A CA  1 
ATOM 2374 C C   . PRO C 3 94  ? 171.477 185.001 156.849 1.00 51.62  ? 426 PRO A C   1 
ATOM 2375 O O   . PRO C 3 94  ? 172.398 184.255 156.511 1.00 51.62  ? 426 PRO A O   1 
ATOM 2376 C CB  . PRO C 3 94  ? 169.196 183.942 157.020 1.00 51.62  ? 426 PRO A CB  1 
ATOM 2377 C CG  . PRO C 3 94  ? 169.319 182.644 156.310 1.00 51.62  ? 426 PRO A CG  1 
ATOM 2378 C CD  . PRO C 3 94  ? 169.492 182.975 154.858 1.00 51.62  ? 426 PRO A CD  1 
ATOM 2379 N N   . ASP C 3 95  ? 171.613 185.956 157.772 1.00 57.97  ? 427 ASP A N   1 
ATOM 2380 C CA  . ASP C 3 95  ? 172.890 186.155 158.453 1.00 57.97  ? 427 ASP A CA  1 
ATOM 2381 C C   . ASP C 3 95  ? 173.300 184.915 159.237 1.00 57.97  ? 427 ASP A C   1 
ATOM 2382 O O   . ASP C 3 95  ? 174.461 184.492 159.183 1.00 57.97  ? 427 ASP A O   1 
ATOM 2383 C CB  . ASP C 3 95  ? 172.804 187.368 159.379 1.00 57.97  ? 427 ASP A CB  1 
ATOM 2384 C CG  . ASP C 3 95  ? 173.298 188.639 158.722 1.00 57.97  ? 427 ASP A CG  1 
ATOM 2385 O OD1 . ASP C 3 95  ? 174.292 188.571 157.971 1.00 57.97  ? 427 ASP A OD1 1 
ATOM 2386 O OD2 . ASP C 3 95  ? 172.694 189.707 158.957 1.00 57.97  ? 427 ASP A OD2 1 
ATOM 2387 N N   . ASP C 3 96  ? 172.363 184.317 159.969 1.00 56.38  ? 428 ASP A N   1 
ATOM 2388 C CA  . ASP C 3 96  ? 172.637 183.109 160.742 1.00 56.38  ? 428 ASP A CA  1 
ATOM 2389 C C   . ASP C 3 96  ? 172.198 181.882 159.941 1.00 56.38  ? 428 ASP A C   1 
ATOM 2390 O O   . ASP C 3 96  ? 171.117 181.322 160.124 1.00 56.38  ? 428 ASP A O   1 
ATOM 2391 C CB  . ASP C 3 96  ? 171.943 183.179 162.100 1.00 56.38  ? 428 ASP A CB  1 
ATOM 2392 C CG  . ASP C 3 96  ? 170.516 183.679 162.001 1.00 56.38  ? 428 ASP A CG  1 
ATOM 2393 O OD1 . ASP C 3 96  ? 170.072 183.995 160.878 1.00 56.38  ? 428 ASP A OD1 1 
ATOM 2394 O OD2 . ASP C 3 96  ? 169.838 183.755 163.047 1.00 56.38  ? 428 ASP A OD2 1 
ATOM 2395 N N   . PHE C 3 97  ? 173.079 181.474 159.034 1.00 46.15  ? 429 PHE A N   1 
ATOM 2396 C CA  . PHE C 3 97  ? 172.810 180.359 158.140 1.00 46.15  ? 429 PHE A CA  1 
ATOM 2397 C C   . PHE C 3 97  ? 173.500 179.099 158.644 1.00 46.15  ? 429 PHE A C   1 
ATOM 2398 O O   . PHE C 3 97  ? 174.666 179.134 159.048 1.00 46.15  ? 429 PHE A O   1 
ATOM 2399 C CB  . PHE C 3 97  ? 173.281 180.688 156.724 1.00 46.15  ? 429 PHE A CB  1 
ATOM 2400 C CG  . PHE C 3 97  ? 172.789 179.730 155.686 1.00 46.15  ? 429 PHE A CG  1 
ATOM 2401 C CD1 . PHE C 3 97  ? 171.445 179.418 155.600 1.00 46.15  ? 429 PHE A CD1 1 
ATOM 2402 C CD2 . PHE C 3 97  ? 173.666 179.149 154.789 1.00 46.15  ? 429 PHE A CD2 1 
ATOM 2403 C CE1 . PHE C 3 97  ? 170.987 178.540 154.644 1.00 46.15  ? 429 PHE A CE1 1 
ATOM 2404 C CE2 . PHE C 3 97  ? 173.213 178.269 153.831 1.00 46.15  ? 429 PHE A CE2 1 
ATOM 2405 C CZ  . PHE C 3 97  ? 171.871 177.965 153.759 1.00 46.15  ? 429 PHE A CZ  1 
ATOM 2406 N N   . THR C 3 98  ? 172.771 177.987 158.619 1.00 43.34  ? 430 THR A N   1 
ATOM 2407 C CA  . THR C 3 98  ? 173.245 176.704 159.130 1.00 43.34  ? 430 THR A CA  1 
ATOM 2408 C C   . THR C 3 98  ? 173.114 175.622 158.066 1.00 43.34  ? 430 THR A C   1 
ATOM 2409 O O   . THR C 3 98  ? 172.623 174.521 158.319 1.00 43.34  ? 430 THR A O   1 
ATOM 2410 C CB  . THR C 3 98  ? 172.485 176.297 160.388 1.00 43.34  ? 430 THR A CB  1 
ATOM 2411 O OG1 . THR C 3 98  ? 171.094 176.150 160.079 1.00 43.34  ? 430 THR A OG1 1 
ATOM 2412 C CG2 . THR C 3 98  ? 172.649 177.346 161.477 1.00 43.34  ? 430 THR A CG2 1 
ATOM 2413 N N   . GLY C 3 99  ? 173.559 175.925 156.851 1.00 36.41  ? 431 GLY A N   1 
ATOM 2414 C CA  . GLY C 3 99  ? 173.443 174.971 155.767 1.00 36.41  ? 431 GLY A CA  1 
ATOM 2415 C C   . GLY C 3 99  ? 174.670 174.869 154.887 1.00 36.41  ? 431 GLY A C   1 
ATOM 2416 O O   . GLY C 3 99  ? 175.792 175.110 155.339 1.00 36.41  ? 431 GLY A O   1 
ATOM 2417 N N   . CYS C 3 100 ? 174.463 174.512 153.622 1.00 32.05  ? 432 CYS A N   1 
ATOM 2418 C CA  . CYS C 3 100 ? 175.542 174.356 152.661 1.00 32.05  ? 432 CYS A CA  1 
ATOM 2419 C C   . CYS C 3 100 ? 175.183 175.085 151.376 1.00 32.05  ? 432 CYS A C   1 
ATOM 2420 O O   . CYS C 3 100 ? 174.011 175.326 151.081 1.00 32.05  ? 432 CYS A O   1 
ATOM 2421 C CB  . CYS C 3 100 ? 175.821 172.879 152.355 1.00 32.05  ? 432 CYS A CB  1 
ATOM 2422 S SG  . CYS C 3 100 ? 176.487 171.933 153.737 1.00 32.05  ? 432 CYS A SG  1 
ATOM 2423 N N   . VAL C 3 101 ? 176.212 175.445 150.615 1.00 26.96  ? 433 VAL A N   1 
ATOM 2424 C CA  . VAL C 3 101 ? 176.055 176.072 149.310 1.00 26.96  ? 433 VAL A CA  1 
ATOM 2425 C C   . VAL C 3 101 ? 176.852 175.261 148.302 1.00 26.96  ? 433 VAL A C   1 
ATOM 2426 O O   . VAL C 3 101 ? 178.040 174.997 148.513 1.00 26.96  ? 433 VAL A O   1 
ATOM 2427 C CB  . VAL C 3 101 ? 176.520 177.539 149.313 1.00 26.96  ? 433 VAL A CB  1 
ATOM 2428 C CG1 . VAL C 3 101 ? 176.491 178.101 147.904 1.00 26.96  ? 433 VAL A CG1 1 
ATOM 2429 C CG2 . VAL C 3 101 ? 175.648 178.367 150.237 1.00 26.96  ? 433 VAL A CG2 1 
ATOM 2430 N N   . ILE C 3 102 ? 176.203 174.865 147.213 1.00 24.14  ? 434 ILE A N   1 
ATOM 2431 C CA  . ILE C 3 102 ? 176.806 174.000 146.210 1.00 24.14  ? 434 ILE A CA  1 
ATOM 2432 C C   . ILE C 3 102 ? 176.613 174.640 144.847 1.00 24.14  ? 434 ILE A C   1 
ATOM 2433 O O   . ILE C 3 102 ? 175.509 175.083 144.521 1.00 24.14  ? 434 ILE A O   1 
ATOM 2434 C CB  . ILE C 3 102 ? 176.187 172.593 146.237 1.00 24.14  ? 434 ILE A CB  1 
ATOM 2435 C CG1 . ILE C 3 102 ? 176.547 171.902 147.543 1.00 24.14  ? 434 ILE A CG1 1 
ATOM 2436 C CG2 . ILE C 3 102 ? 176.681 171.775 145.065 1.00 24.14  ? 434 ILE A CG2 1 
ATOM 2437 C CD1 . ILE C 3 102 ? 175.551 170.892 148.005 1.00 24.14  ? 434 ILE A CD1 1 
ATOM 2438 N N   . ALA C 3 103 ? 177.679 174.694 144.056 1.00 24.61  ? 435 ALA A N   1 
ATOM 2439 C CA  . ALA C 3 103 ? 177.594 175.231 142.708 1.00 24.61  ? 435 ALA A CA  1 
ATOM 2440 C C   . ALA C 3 103 ? 178.614 174.525 141.834 1.00 24.61  ? 435 ALA A C   1 
ATOM 2441 O O   . ALA C 3 103 ? 179.734 174.259 142.274 1.00 24.61  ? 435 ALA A O   1 
ATOM 2442 C CB  . ALA C 3 103 ? 177.835 176.742 142.691 1.00 24.61  ? 435 ALA A CB  1 
ATOM 2443 N N   . TRP C 3 104 ? 178.227 174.226 140.598 1.00 28.45  ? 436 TRP A N   1 
ATOM 2444 C CA  . TRP C 3 104 ? 179.125 173.566 139.667 1.00 28.45  ? 436 TRP A CA  1 
ATOM 2445 C C   . TRP C 3 104 ? 178.895 174.107 138.265 1.00 28.45  ? 436 TRP A C   1 
ATOM 2446 O O   . TRP C 3 104 ? 177.858 174.701 137.966 1.00 28.45  ? 436 TRP A O   1 
ATOM 2447 C CB  . TRP C 3 104 ? 178.950 172.043 139.683 1.00 28.45  ? 436 TRP A CB  1 
ATOM 2448 C CG  . TRP C 3 104 ? 177.582 171.563 139.322 1.00 28.45  ? 436 TRP A CG  1 
ATOM 2449 C CD1 . TRP C 3 104 ? 177.193 171.037 138.127 1.00 28.45  ? 436 TRP A CD1 1 
ATOM 2450 C CD2 . TRP C 3 104 ? 176.428 171.532 140.169 1.00 28.45  ? 436 TRP A CD2 1 
ATOM 2451 N NE1 . TRP C 3 104 ? 175.865 170.693 138.171 1.00 28.45  ? 436 TRP A NE1 1 
ATOM 2452 C CE2 . TRP C 3 104 ? 175.373 170.987 139.415 1.00 28.45  ? 436 TRP A CE2 1 
ATOM 2453 C CE3 . TRP C 3 104 ? 176.183 171.918 141.488 1.00 28.45  ? 436 TRP A CE3 1 
ATOM 2454 C CZ2 . TRP C 3 104 ? 174.097 170.819 139.935 1.00 28.45  ? 436 TRP A CZ2 1 
ATOM 2455 C CZ3 . TRP C 3 104 ? 174.914 171.749 142.001 1.00 28.45  ? 436 TRP A CZ3 1 
ATOM 2456 C CH2 . TRP C 3 104 ? 173.889 171.205 141.227 1.00 28.45  ? 436 TRP A CH2 1 
ATOM 2457 N N   . ASN C 3 105 ? 179.891 173.897 137.408 1.00 38.74  ? 437 ASN A N   1 
ATOM 2458 C CA  . ASN C 3 105 ? 179.813 174.382 136.038 1.00 38.74  ? 437 ASN A CA  1 
ATOM 2459 C C   . ASN C 3 105 ? 178.671 173.707 135.293 1.00 38.74  ? 437 ASN A C   1 
ATOM 2460 O O   . ASN C 3 105 ? 178.440 172.503 135.431 1.00 38.74  ? 437 ASN A O   1 
ATOM 2461 C CB  . ASN C 3 105 ? 181.135 174.131 135.313 1.00 38.74  ? 437 ASN A CB  1 
ATOM 2462 C CG  . ASN C 3 105 ? 181.544 175.293 134.435 1.00 38.74  ? 437 ASN A CG  1 
ATOM 2463 O OD1 . ASN C 3 105 ? 180.712 176.105 134.034 1.00 38.74  ? 437 ASN A OD1 1 
ATOM 2464 N ND2 . ASN C 3 105 ? 182.833 175.379 134.129 1.00 38.74  ? 437 ASN A ND2 1 
ATOM 2465 N N   . SER C 3 106 ? 177.953 174.496 134.498 1.00 43.25  ? 438 SER A N   1 
ATOM 2466 C CA  . SER C 3 106 ? 176.838 174.001 133.702 1.00 43.25  ? 438 SER A CA  1 
ATOM 2467 C C   . SER C 3 106 ? 176.903 174.541 132.281 1.00 43.25  ? 438 SER A C   1 
ATOM 2468 O O   . SER C 3 106 ? 175.869 174.789 131.657 1.00 43.25  ? 438 SER A O   1 
ATOM 2469 C CB  . SER C 3 106 ? 175.506 174.367 134.350 1.00 43.25  ? 438 SER A CB  1 
ATOM 2470 O OG  . SER C 3 106 ? 175.318 175.770 134.344 1.00 43.25  ? 438 SER A OG  1 
ATOM 2471 N N   . ASN C 3 107 ? 178.117 174.725 131.760 1.00 49.22  ? 439 ASN A N   1 
ATOM 2472 C CA  . ASN C 3 107 ? 178.276 175.323 130.440 1.00 49.22  ? 439 ASN A CA  1 
ATOM 2473 C C   . ASN C 3 107 ? 177.661 174.449 129.355 1.00 49.22  ? 439 ASN A C   1 
ATOM 2474 O O   . ASN C 3 107 ? 177.052 174.960 128.407 1.00 49.22  ? 439 ASN A O   1 
ATOM 2475 C CB  . ASN C 3 107 ? 179.757 175.568 130.157 1.00 49.22  ? 439 ASN A CB  1 
ATOM 2476 C CG  . ASN C 3 107 ? 179.980 176.643 129.117 1.00 49.22  ? 439 ASN A CG  1 
ATOM 2477 O OD1 . ASN C 3 107 ? 179.040 177.313 128.692 1.00 49.22  ? 439 ASN A OD1 1 
ATOM 2478 N ND2 . ASN C 3 107 ? 181.229 176.813 128.700 1.00 49.22  ? 439 ASN A ND2 1 
ATOM 2479 N N   . ASN C 3 108 ? 177.808 173.133 129.472 1.00 54.93  ? 440 ASN A N   1 
ATOM 2480 C CA  . ASN C 3 108 ? 177.307 172.206 128.467 1.00 54.93  ? 440 ASN A CA  1 
ATOM 2481 C C   . ASN C 3 108 ? 175.889 171.726 128.747 1.00 54.93  ? 440 ASN A C   1 
ATOM 2482 O O   . ASN C 3 108 ? 175.378 170.886 127.999 1.00 54.93  ? 440 ASN A O   1 
ATOM 2483 C CB  . ASN C 3 108 ? 178.242 170.997 128.351 1.00 54.93  ? 440 ASN A CB  1 
ATOM 2484 C CG  . ASN C 3 108 ? 178.267 170.153 129.612 1.00 54.93  ? 440 ASN A CG  1 
ATOM 2485 O OD1 . ASN C 3 108 ? 177.858 170.600 130.683 1.00 54.93  ? 440 ASN A OD1 1 
ATOM 2486 N ND2 . ASN C 3 108 ? 178.746 168.921 129.488 1.00 54.93  ? 440 ASN A ND2 1 
ATOM 2487 N N   . LEU C 3 109 ? 175.241 172.233 129.794 1.00 52.74  ? 441 LEU A N   1 
ATOM 2488 C CA  . LEU C 3 109 ? 173.928 171.749 130.200 1.00 52.74  ? 441 LEU A CA  1 
ATOM 2489 C C   . LEU C 3 109 ? 172.823 172.759 129.915 1.00 52.74  ? 441 LEU A C   1 
ATOM 2490 O O   . LEU C 3 109 ? 171.842 172.427 129.244 1.00 52.74  ? 441 LEU A O   1 
ATOM 2491 C CB  . LEU C 3 109 ? 173.944 171.384 131.691 1.00 52.74  ? 441 LEU A CB  1 
ATOM 2492 N N   . ASP C 3 110 ? 172.955 173.988 130.405 1.00 47.72  ? 442 ASP A N   1 
ATOM 2493 C CA  . ASP C 3 110 ? 171.907 174.995 130.297 1.00 47.72  ? 442 ASP A CA  1 
ATOM 2494 C C   . ASP C 3 110 ? 172.408 176.281 129.645 1.00 47.72  ? 442 ASP A C   1 
ATOM 2495 O O   . ASP C 3 110 ? 171.941 177.379 129.952 1.00 47.72  ? 442 ASP A O   1 
ATOM 2496 C CB  . ASP C 3 110 ? 171.271 175.250 131.667 1.00 47.72  ? 442 ASP A CB  1 
ATOM 2497 C CG  . ASP C 3 110 ? 172.205 175.948 132.656 1.00 47.72  ? 442 ASP A CG  1 
ATOM 2498 O OD1 . ASP C 3 110 ? 172.010 175.739 133.870 1.00 47.72  ? 442 ASP A OD1 1 
ATOM 2499 O OD2 . ASP C 3 110 ? 173.132 176.681 132.258 1.00 47.72  ? 442 ASP A OD2 1 
ATOM 2500 N N   . SER C 3 111 ? 173.350 176.155 128.712 1.00 52.73  ? 443 SER A N   1 
ATOM 2501 C CA  . SER C 3 111 ? 173.867 177.302 127.966 1.00 52.73  ? 443 SER A CA  1 
ATOM 2502 C C   . SER C 3 111 ? 173.922 176.909 126.494 1.00 52.73  ? 443 SER A C   1 
ATOM 2503 O O   . SER C 3 111 ? 174.919 176.348 126.031 1.00 52.73  ? 443 SER A O   1 
ATOM 2504 C CB  . SER C 3 111 ? 175.237 177.729 128.479 1.00 52.73  ? 443 SER A CB  1 
ATOM 2505 O OG  . SER C 3 111 ? 175.866 178.611 127.567 1.00 52.73  ? 443 SER A OG  1 
ATOM 2506 N N   . LYS C 3 112 ? 172.851 177.207 125.765 1.00 58.11  ? 444 LYS A N   1 
ATOM 2507 C CA  . LYS C 3 112 ? 172.750 176.863 124.357 1.00 58.11  ? 444 LYS A CA  1 
ATOM 2508 C C   . LYS C 3 112 ? 173.531 177.855 123.500 1.00 58.11  ? 444 LYS A C   1 
ATOM 2509 O O   . LYS C 3 112 ? 173.856 178.965 123.927 1.00 58.11  ? 444 LYS A O   1 
ATOM 2510 C CB  . LYS C 3 112 ? 171.286 176.827 123.915 1.00 58.11  ? 444 LYS A CB  1 
ATOM 2511 N N   . VAL C 3 113 ? 173.829 177.433 122.271 1.00 60.74  ? 445 VAL A N   1 
ATOM 2512 C CA  . VAL C 3 113 ? 174.585 178.271 121.350 1.00 60.74  ? 445 VAL A CA  1 
ATOM 2513 C C   . VAL C 3 113 ? 173.724 179.442 120.894 1.00 60.74  ? 445 VAL A C   1 
ATOM 2514 O O   . VAL C 3 113 ? 172.531 179.287 120.598 1.00 60.74  ? 445 VAL A O   1 
ATOM 2515 C CB  . VAL C 3 113 ? 175.086 177.436 120.157 1.00 60.74  ? 445 VAL A CB  1 
ATOM 2516 C CG1 . VAL C 3 113 ? 173.931 176.706 119.485 1.00 60.74  ? 445 VAL A CG1 1 
ATOM 2517 C CG2 . VAL C 3 113 ? 175.827 178.313 119.157 1.00 60.74  ? 445 VAL A CG2 1 
ATOM 2518 N N   . GLY C 3 114 ? 174.326 180.630 120.851 1.00 59.87  ? 446 GLY A N   1 
ATOM 2519 C CA  . GLY C 3 114 ? 173.638 181.829 120.429 1.00 59.87  ? 446 GLY A CA  1 
ATOM 2520 C C   . GLY C 3 114 ? 172.979 182.621 121.538 1.00 59.87  ? 446 GLY A C   1 
ATOM 2521 O O   . GLY C 3 114 ? 172.483 183.724 121.277 1.00 59.87  ? 446 GLY A O   1 
ATOM 2522 N N   . GLY C 3 115 ? 172.957 182.101 122.762 1.00 57.43  ? 447 GLY A N   1 
ATOM 2523 C CA  . GLY C 3 115 ? 172.372 182.822 123.874 1.00 57.43  ? 447 GLY A CA  1 
ATOM 2524 C C   . GLY C 3 115 ? 171.084 182.212 124.385 1.00 57.43  ? 447 GLY A C   1 
ATOM 2525 O O   . GLY C 3 115 ? 170.047 182.289 123.720 1.00 57.43  ? 447 GLY A O   1 
ATOM 2526 N N   . ASN C 3 116 ? 171.136 181.604 125.568 1.00 56.05  ? 448 ASN A N   1 
ATOM 2527 C CA  . ASN C 3 116 ? 169.957 181.014 126.194 1.00 56.05  ? 448 ASN A CA  1 
ATOM 2528 C C   . ASN C 3 116 ? 169.321 182.055 127.107 1.00 56.05  ? 448 ASN A C   1 
ATOM 2529 O O   . ASN C 3 116 ? 169.871 182.386 128.162 1.00 56.05  ? 448 ASN A O   1 
ATOM 2530 C CB  . ASN C 3 116 ? 170.330 179.754 126.970 1.00 56.05  ? 448 ASN A CB  1 
ATOM 2531 C CG  . ASN C 3 116 ? 169.115 178.956 127.400 1.00 56.05  ? 448 ASN A CG  1 
ATOM 2532 O OD1 . ASN C 3 116 ? 168.012 179.164 126.895 1.00 56.05  ? 448 ASN A OD1 1 
ATOM 2533 N ND2 . ASN C 3 116 ? 169.311 178.038 128.339 1.00 56.05  ? 448 ASN A ND2 1 
ATOM 2534 N N   . TYR C 3 117 ? 168.161 182.567 126.702 1.00 57.45  ? 449 TYR A N   1 
ATOM 2535 C CA  . TYR C 3 117 ? 167.468 183.623 127.426 1.00 57.45  ? 449 TYR A CA  1 
ATOM 2536 C C   . TYR C 3 117 ? 166.376 183.086 128.341 1.00 57.45  ? 449 TYR A C   1 
ATOM 2537 O O   . TYR C 3 117 ? 165.451 183.827 128.688 1.00 57.45  ? 449 TYR A O   1 
ATOM 2538 C CB  . TYR C 3 117 ? 166.876 184.630 126.438 1.00 57.45  ? 449 TYR A CB  1 
ATOM 2539 C CG  . TYR C 3 117 ? 167.892 185.204 125.477 1.00 57.45  ? 449 TYR A CG  1 
ATOM 2540 C CD1 . TYR C 3 117 ? 169.144 185.609 125.920 1.00 57.45  ? 449 TYR A CD1 1 
ATOM 2541 C CD2 . TYR C 3 117 ? 167.604 185.331 124.125 1.00 57.45  ? 449 TYR A CD2 1 
ATOM 2542 C CE1 . TYR C 3 117 ? 170.078 186.130 125.047 1.00 57.45  ? 449 TYR A CE1 1 
ATOM 2543 C CE2 . TYR C 3 117 ? 168.532 185.852 123.243 1.00 57.45  ? 449 TYR A CE2 1 
ATOM 2544 C CZ  . TYR C 3 117 ? 169.767 186.249 123.710 1.00 57.45  ? 449 TYR A CZ  1 
ATOM 2545 O OH  . TYR C 3 117 ? 170.694 186.768 122.836 1.00 57.45  ? 449 TYR A OH  1 
ATOM 2546 N N   . ASN C 3 118 ? 166.463 181.818 128.740 1.00 50.34  ? 450 ASN A N   1 
ATOM 2547 C CA  . ASN C 3 118 ? 165.427 181.190 129.548 1.00 50.34  ? 450 ASN A CA  1 
ATOM 2548 C C   . ASN C 3 118 ? 165.546 181.548 131.027 1.00 50.34  ? 450 ASN A C   1 
ATOM 2549 O O   . ASN C 3 118 ? 164.590 181.341 131.780 1.00 50.34  ? 450 ASN A O   1 
ATOM 2550 C CB  . ASN C 3 118 ? 165.502 179.668 129.358 1.00 50.34  ? 450 ASN A CB  1 
ATOM 2551 C CG  . ASN C 3 118 ? 164.295 178.929 129.921 1.00 50.34  ? 450 ASN A CG  1 
ATOM 2552 O OD1 . ASN C 3 118 ? 163.369 179.528 130.464 1.00 50.34  ? 450 ASN A OD1 1 
ATOM 2553 N ND2 . ASN C 3 118 ? 164.308 177.608 129.788 1.00 50.34  ? 450 ASN A ND2 1 
ATOM 2554 N N   . TYR C 3 119 ? 166.672 182.109 131.457 1.00 42.72  ? 451 TYR A N   1 
ATOM 2555 C CA  . TYR C 3 119 ? 166.922 182.378 132.866 1.00 42.72  ? 451 TYR A CA  1 
ATOM 2556 C C   . TYR C 3 119 ? 166.816 183.873 133.122 1.00 42.72  ? 451 TYR A C   1 
ATOM 2557 O O   . TYR C 3 119 ? 167.366 184.677 132.363 1.00 42.72  ? 451 TYR A O   1 
ATOM 2558 C CB  . TYR C 3 119 ? 168.295 181.854 133.288 1.00 42.72  ? 451 TYR A CB  1 
ATOM 2559 C CG  . TYR C 3 119 ? 168.360 180.345 133.320 1.00 42.72  ? 451 TYR A CG  1 
ATOM 2560 C CD1 . TYR C 3 119 ? 168.482 179.614 132.146 1.00 42.72  ? 451 TYR A CD1 1 
ATOM 2561 C CD2 . TYR C 3 119 ? 168.259 179.651 134.514 1.00 42.72  ? 451 TYR A CD2 1 
ATOM 2562 C CE1 . TYR C 3 119 ? 168.529 178.236 132.165 1.00 42.72  ? 451 TYR A CE1 1 
ATOM 2563 C CE2 . TYR C 3 119 ? 168.301 178.272 134.541 1.00 42.72  ? 451 TYR A CE2 1 
ATOM 2564 C CZ  . TYR C 3 119 ? 168.437 177.571 133.365 1.00 42.72  ? 451 TYR A CZ  1 
ATOM 2565 O OH  . TYR C 3 119 ? 168.481 176.198 133.391 1.00 42.72  ? 451 TYR A OH  1 
ATOM 2566 N N   . LEU C 3 120 ? 166.114 184.239 134.192 1.00 42.76  ? 452 LEU A N   1 
ATOM 2567 C CA  . LEU C 3 120 ? 165.767 185.623 134.470 1.00 42.76  ? 452 LEU A CA  1 
ATOM 2568 C C   . LEU C 3 120 ? 166.211 185.996 135.877 1.00 42.76  ? 452 LEU A C   1 
ATOM 2569 O O   . LEU C 3 120 ? 166.384 185.137 136.743 1.00 42.76  ? 452 LEU A O   1 
ATOM 2570 C CB  . LEU C 3 120 ? 164.258 185.852 134.319 1.00 42.76  ? 452 LEU A CB  1 
ATOM 2571 C CG  . LEU C 3 120 ? 163.683 185.692 132.910 1.00 42.76  ? 452 LEU A CG  1 
ATOM 2572 C CD1 . LEU C 3 120 ? 162.170 185.807 132.932 1.00 42.76  ? 452 LEU A CD1 1 
ATOM 2573 C CD2 . LEU C 3 120 ? 164.283 186.714 131.961 1.00 42.76  ? 452 LEU A CD2 1 
ATOM 2574 N N   . TYR C 3 121 ? 166.397 187.295 136.096 1.00 46.32  ? 453 TYR A N   1 
ATOM 2575 C CA  . TYR C 3 121 ? 166.764 187.792 137.413 1.00 46.32  ? 453 TYR A CA  1 
ATOM 2576 C C   . TYR C 3 121 ? 166.258 189.219 137.561 1.00 46.32  ? 453 TYR A C   1 
ATOM 2577 O O   . TYR C 3 121 ? 165.993 189.910 136.574 1.00 46.32  ? 453 TYR A O   1 
ATOM 2578 C CB  . TYR C 3 121 ? 168.277 187.720 137.634 1.00 46.32  ? 453 TYR A CB  1 
ATOM 2579 C CG  . TYR C 3 121 ? 169.077 188.721 136.839 1.00 46.32  ? 453 TYR A CG  1 
ATOM 2580 C CD1 . TYR C 3 121 ? 169.390 188.489 135.510 1.00 46.32  ? 453 TYR A CD1 1 
ATOM 2581 C CD2 . TYR C 3 121 ? 169.570 189.871 137.434 1.00 46.32  ? 453 TYR A CD2 1 
ATOM 2582 C CE1 . TYR C 3 121 ? 170.134 189.392 134.782 1.00 46.32  ? 453 TYR A CE1 1 
ATOM 2583 C CE2 . TYR C 3 121 ? 170.322 190.774 136.718 1.00 46.32  ? 453 TYR A CE2 1 
ATOM 2584 C CZ  . TYR C 3 121 ? 170.599 190.532 135.392 1.00 46.32  ? 453 TYR A CZ  1 
ATOM 2585 O OH  . TYR C 3 121 ? 171.345 191.433 134.670 1.00 46.32  ? 453 TYR A OH  1 
ATOM 2586 N N   . ARG C 3 122 ? 166.136 189.657 138.811 1.00 49.68  ? 454 ARG A N   1 
ATOM 2587 C CA  . ARG C 3 122 ? 165.533 190.947 139.129 1.00 49.68  ? 454 ARG A CA  1 
ATOM 2588 C C   . ARG C 3 122 ? 166.622 192.011 139.218 1.00 49.68  ? 454 ARG A C   1 
ATOM 2589 O O   . ARG C 3 122 ? 167.403 192.032 140.174 1.00 49.68  ? 454 ARG A O   1 
ATOM 2590 C CB  . ARG C 3 122 ? 164.749 190.866 140.436 1.00 49.68  ? 454 ARG A CB  1 
ATOM 2591 C CG  . ARG C 3 122 ? 163.473 190.054 140.345 1.00 49.68  ? 454 ARG A CG  1 
ATOM 2592 C CD  . ARG C 3 122 ? 162.733 190.046 141.669 1.00 49.68  ? 454 ARG A CD  1 
ATOM 2593 N NE  . ARG C 3 122 ? 161.862 191.206 141.812 1.00 49.68  ? 454 ARG A NE  1 
ATOM 2594 C CZ  . ARG C 3 122 ? 160.658 191.307 141.267 1.00 49.68  ? 454 ARG A CZ  1 
ATOM 2595 N NH1 . ARG C 3 122 ? 160.148 190.333 140.532 1.00 49.68  ? 454 ARG A NH1 1 
ATOM 2596 N NH2 . ARG C 3 122 ? 159.947 192.414 141.466 1.00 49.68  ? 454 ARG A NH2 1 
ATOM 2597 N N   . LEU C 3 123 ? 166.674 192.893 138.217 1.00 53.30  ? 455 LEU A N   1 
ATOM 2598 C CA  . LEU C 3 123 ? 167.566 194.045 138.295 1.00 53.30  ? 455 LEU A CA  1 
ATOM 2599 C C   . LEU C 3 123 ? 167.163 194.985 139.421 1.00 53.30  ? 455 LEU A C   1 
ATOM 2600 O O   . LEU C 3 123 ? 168.016 195.459 140.180 1.00 53.30  ? 455 LEU A O   1 
ATOM 2601 C CB  . LEU C 3 123 ? 167.572 194.804 136.968 1.00 53.30  ? 455 LEU A CB  1 
ATOM 2602 C CG  . LEU C 3 123 ? 168.141 194.160 135.709 1.00 53.30  ? 455 LEU A CG  1 
ATOM 2603 C CD1 . LEU C 3 123 ? 167.887 195.067 134.531 1.00 53.30  ? 455 LEU A CD1 1 
ATOM 2604 C CD2 . LEU C 3 123 ? 169.626 193.966 135.883 1.00 53.30  ? 455 LEU A CD2 1 
ATOM 2605 N N   . PHE C 3 124 ? 165.869 195.267 139.546 1.00 54.56  ? 456 PHE A N   1 
ATOM 2606 C CA  . PHE C 3 124 ? 165.387 196.328 140.415 1.00 54.56  ? 456 PHE A CA  1 
ATOM 2607 C C   . PHE C 3 124 ? 164.292 195.814 141.334 1.00 54.56  ? 456 PHE A C   1 
ATOM 2608 O O   . PHE C 3 124 ? 163.492 194.957 140.949 1.00 54.56  ? 456 PHE A O   1 
ATOM 2609 C CB  . PHE C 3 124 ? 164.849 197.503 139.596 1.00 54.56  ? 456 PHE A CB  1 
ATOM 2610 C CG  . PHE C 3 124 ? 165.621 197.768 138.336 1.00 54.56  ? 456 PHE A CG  1 
ATOM 2611 C CD1 . PHE C 3 124 ? 165.059 197.507 137.100 1.00 54.56  ? 456 PHE A CD1 1 
ATOM 2612 C CD2 . PHE C 3 124 ? 166.900 198.291 138.388 1.00 54.56  ? 456 PHE A CD2 1 
ATOM 2613 C CE1 . PHE C 3 124 ? 165.762 197.749 135.940 1.00 54.56  ? 456 PHE A CE1 1 
ATOM 2614 C CE2 . PHE C 3 124 ? 167.607 198.539 137.228 1.00 54.56  ? 456 PHE A CE2 1 
ATOM 2615 C CZ  . PHE C 3 124 ? 167.036 198.268 136.003 1.00 54.56  ? 456 PHE A CZ  1 
ATOM 2616 N N   . ARG C 3 125 ? 164.265 196.348 142.552 1.00 59.95  ? 457 ARG A N   1 
ATOM 2617 C CA  . ARG C 3 125 ? 163.175 196.104 143.481 1.00 59.95  ? 457 ARG A CA  1 
ATOM 2618 C C   . ARG C 3 125 ? 163.096 197.300 144.419 1.00 59.95  ? 457 ARG A C   1 
ATOM 2619 O O   . ARG C 3 125 ? 164.053 198.068 144.553 1.00 59.95  ? 457 ARG A O   1 
ATOM 2620 C CB  . ARG C 3 125 ? 163.373 194.786 144.246 1.00 59.95  ? 457 ARG A CB  1 
ATOM 2621 C CG  . ARG C 3 125 ? 162.229 194.416 145.179 1.00 59.95  ? 457 ARG A CG  1 
ATOM 2622 C CD  . ARG C 3 125 ? 162.456 193.085 145.864 1.00 59.95  ? 457 ARG A CD  1 
ATOM 2623 N NE  . ARG C 3 125 ? 161.328 192.735 146.717 1.00 59.95  ? 457 ARG A NE  1 
ATOM 2624 C CZ  . ARG C 3 125 ? 161.224 193.077 147.994 1.00 59.95  ? 457 ARG A CZ  1 
ATOM 2625 N NH1 . ARG C 3 125 ? 162.164 193.785 148.598 1.00 59.95  ? 457 ARG A NH1 1 
ATOM 2626 N NH2 . ARG C 3 125 ? 160.148 192.703 148.680 1.00 59.95  ? 457 ARG A NH2 1 
ATOM 2627 N N   . LYS C 3 126 ? 161.937 197.459 145.064 1.00 62.16  ? 458 LYS A N   1 
ATOM 2628 C CA  . LYS C 3 126 ? 161.725 198.616 145.928 1.00 62.16  ? 458 LYS A CA  1 
ATOM 2629 C C   . LYS C 3 126 ? 162.732 198.644 147.072 1.00 62.16  ? 458 LYS A C   1 
ATOM 2630 O O   . LYS C 3 126 ? 163.276 199.703 147.404 1.00 62.16  ? 458 LYS A O   1 
ATOM 2631 C CB  . LYS C 3 126 ? 160.297 198.612 146.475 1.00 62.16  ? 458 LYS A CB  1 
ATOM 2632 C CG  . LYS C 3 126 ? 159.199 198.473 145.423 1.00 62.16  ? 458 LYS A CG  1 
ATOM 2633 C CD  . LYS C 3 126 ? 159.511 199.250 144.152 1.00 62.16  ? 458 LYS A CD  1 
ATOM 2634 C CE  . LYS C 3 126 ? 158.427 199.053 143.106 1.00 62.16  ? 458 LYS A CE  1 
ATOM 2635 N NZ  . LYS C 3 126 ? 157.177 199.780 143.458 1.00 62.16  ? 458 LYS A NZ  1 
ATOM 2636 N N   . SER C 3 127 ? 162.997 197.491 147.681 1.00 62.48  ? 459 SER A N   1 
ATOM 2637 C CA  . SER C 3 127 ? 163.968 197.399 148.761 1.00 62.48  ? 459 SER A CA  1 
ATOM 2638 C C   . SER C 3 127 ? 164.555 195.993 148.774 1.00 62.48  ? 459 SER A C   1 
ATOM 2639 O O   . SER C 3 127 ? 164.170 195.128 147.983 1.00 62.48  ? 459 SER A O   1 
ATOM 2640 C CB  . SER C 3 127 ? 163.332 197.758 150.108 1.00 62.48  ? 459 SER A CB  1 
ATOM 2641 O OG  . SER C 3 127 ? 162.393 196.776 150.508 1.00 62.48  ? 459 SER A OG  1 
ATOM 2642 N N   . ASN C 3 128 ? 165.501 195.775 149.682 1.00 55.79  ? 460 ASN A N   1 
ATOM 2643 C CA  . ASN C 3 128 ? 166.145 194.475 149.796 1.00 55.79  ? 460 ASN A CA  1 
ATOM 2644 C C   . ASN C 3 128 ? 165.167 193.440 150.335 1.00 55.79  ? 460 ASN A C   1 
ATOM 2645 O O   . ASN C 3 128 ? 164.357 193.730 151.221 1.00 55.79  ? 460 ASN A O   1 
ATOM 2646 C CB  . ASN C 3 128 ? 167.364 194.569 150.711 1.00 55.79  ? 460 ASN A CB  1 
ATOM 2647 C CG  . ASN C 3 128 ? 168.446 195.466 150.149 1.00 55.79  ? 460 ASN A CG  1 
ATOM 2648 O OD1 . ASN C 3 128 ? 168.722 195.448 148.950 1.00 55.79  ? 460 ASN A OD1 1 
ATOM 2649 N ND2 . ASN C 3 128 ? 169.066 196.260 151.014 1.00 55.79  ? 460 ASN A ND2 1 
ATOM 2650 N N   . LEU C 3 129 ? 165.244 192.227 149.795 1.00 50.46  ? 461 LEU A N   1 
ATOM 2651 C CA  . LEU C 3 129 ? 164.393 191.148 150.273 1.00 50.46  ? 461 LEU A CA  1 
ATOM 2652 C C   . LEU C 3 129 ? 164.774 190.750 151.691 1.00 50.46  ? 461 LEU A C   1 
ATOM 2653 O O   . LEU C 3 129 ? 165.947 190.780 152.070 1.00 50.46  ? 461 LEU A O   1 
ATOM 2654 C CB  . LEU C 3 129 ? 164.502 189.923 149.367 1.00 50.46  ? 461 LEU A CB  1 
ATOM 2655 C CG  . LEU C 3 129 ? 164.157 190.029 147.887 1.00 50.46  ? 461 LEU A CG  1 
ATOM 2656 C CD1 . LEU C 3 129 ? 164.931 188.982 147.117 1.00 50.46  ? 461 LEU A CD1 1 
ATOM 2657 C CD2 . LEU C 3 129 ? 162.667 189.846 147.685 1.00 50.46  ? 461 LEU A CD2 1 
ATOM 2658 N N   . LYS C 3 130 ? 163.770 190.379 152.478 1.00 49.02  ? 462 LYS A N   1 
ATOM 2659 C CA  . LYS C 3 130 ? 164.040 189.687 153.722 1.00 49.02  ? 462 LYS A CA  1 
ATOM 2660 C C   . LYS C 3 130 ? 164.614 188.306 153.410 1.00 49.02  ? 462 LYS A C   1 
ATOM 2661 O O   . LYS C 3 130 ? 164.352 187.749 152.340 1.00 49.02  ? 462 LYS A O   1 
ATOM 2662 C CB  . LYS C 3 130 ? 162.766 189.555 154.550 1.00 49.02  ? 462 LYS A CB  1 
ATOM 2663 N N   . PRO C 3 131 ? 165.417 187.743 154.312 1.00 47.27  ? 463 PRO A N   1 
ATOM 2664 C CA  . PRO C 3 131 ? 166.018 186.432 154.039 1.00 47.27  ? 463 PRO A CA  1 
ATOM 2665 C C   . PRO C 3 131 ? 164.959 185.378 153.752 1.00 47.27  ? 463 PRO A C   1 
ATOM 2666 O O   . PRO C 3 131 ? 163.904 185.342 154.389 1.00 47.27  ? 463 PRO A O   1 
ATOM 2667 C CB  . PRO C 3 131 ? 166.787 186.123 155.326 1.00 47.27  ? 463 PRO A CB  1 
ATOM 2668 C CG  . PRO C 3 131 ? 167.095 187.458 155.902 1.00 47.27  ? 463 PRO A CG  1 
ATOM 2669 C CD  . PRO C 3 131 ? 165.921 188.330 155.565 1.00 47.27  ? 463 PRO A CD  1 
ATOM 2670 N N   . PHE C 3 132 ? 165.254 184.521 152.774 1.00 43.37  ? 464 PHE A N   1 
ATOM 2671 C CA  . PHE C 3 132 ? 164.344 183.464 152.332 1.00 43.37  ? 464 PHE A CA  1 
ATOM 2672 C C   . PHE C 3 132 ? 163.005 184.047 151.875 1.00 43.37  ? 464 PHE A C   1 
ATOM 2673 O O   . PHE C 3 132 ? 161.945 183.764 152.435 1.00 43.37  ? 464 PHE A O   1 
ATOM 2674 C CB  . PHE C 3 132 ? 164.140 182.417 153.432 1.00 43.37  ? 464 PHE A CB  1 
ATOM 2675 C CG  . PHE C 3 132 ? 165.301 181.483 153.605 1.00 43.37  ? 464 PHE A CG  1 
ATOM 2676 C CD1 . PHE C 3 132 ? 165.796 180.766 152.532 1.00 43.37  ? 464 PHE A CD1 1 
ATOM 2677 C CD2 . PHE C 3 132 ? 165.891 181.314 154.845 1.00 43.37  ? 464 PHE A CD2 1 
ATOM 2678 C CE1 . PHE C 3 132 ? 166.859 179.904 152.691 1.00 43.37  ? 464 PHE A CE1 1 
ATOM 2679 C CE2 . PHE C 3 132 ? 166.954 180.453 155.008 1.00 43.37  ? 464 PHE A CE2 1 
ATOM 2680 C CZ  . PHE C 3 132 ? 167.439 179.748 153.929 1.00 43.37  ? 464 PHE A CZ  1 
ATOM 2681 N N   . GLU C 3 133 ? 163.073 184.877 150.838 1.00 39.52  ? 465 GLU A N   1 
ATOM 2682 C CA  . GLU C 3 133 ? 161.891 185.483 150.244 1.00 39.52  ? 465 GLU A CA  1 
ATOM 2683 C C   . GLU C 3 133 ? 161.915 185.269 148.739 1.00 39.52  ? 465 GLU A C   1 
ATOM 2684 O O   . GLU C 3 133 ? 162.967 185.376 148.104 1.00 39.52  ? 465 GLU A O   1 
ATOM 2685 C CB  . GLU C 3 133 ? 161.811 186.980 150.558 1.00 39.52  ? 465 GLU A CB  1 
ATOM 2686 N N   . ARG C 3 134 ? 160.750 184.966 148.174 1.00 40.18  ? 466 ARG A N   1 
ATOM 2687 C CA  . ARG C 3 134 ? 160.601 184.720 146.742 1.00 40.18  ? 466 ARG A CA  1 
ATOM 2688 C C   . ARG C 3 134 ? 159.689 185.799 146.169 1.00 40.18  ? 466 ARG A C   1 
ATOM 2689 O O   . ARG C 3 134 ? 158.473 185.769 146.380 1.00 40.18  ? 466 ARG A O   1 
ATOM 2690 C CB  . ARG C 3 134 ? 160.043 183.326 146.481 1.00 40.18  ? 466 ARG A CB  1 
ATOM 2691 C CG  . ARG C 3 134 ? 160.213 182.849 145.053 1.00 40.18  ? 466 ARG A CG  1 
ATOM 2692 C CD  . ARG C 3 134 ? 159.734 181.420 144.903 1.00 40.18  ? 466 ARG A CD  1 
ATOM 2693 N NE  . ARG C 3 134 ? 159.971 180.650 146.117 1.00 40.18  ? 466 ARG A NE  1 
ATOM 2694 C CZ  . ARG C 3 134 ? 159.770 179.345 146.227 1.00 40.18  ? 466 ARG A CZ  1 
ATOM 2695 N NH1 . ARG C 3 134 ? 159.350 178.623 145.202 1.00 40.18  ? 466 ARG A NH1 1 
ATOM 2696 N NH2 . ARG C 3 134 ? 159.999 178.750 147.393 1.00 40.18  ? 466 ARG A NH2 1 
ATOM 2697 N N   . ASP C 3 135 ? 160.274 186.749 145.445 1.00 49.59  ? 467 ASP A N   1 
ATOM 2698 C CA  . ASP C 3 135 ? 159.510 187.825 144.821 1.00 49.59  ? 467 ASP A CA  1 
ATOM 2699 C C   . ASP C 3 135 ? 159.241 187.470 143.359 1.00 49.59  ? 467 ASP A C   1 
ATOM 2700 O O   . ASP C 3 135 ? 159.769 188.071 142.424 1.00 49.59  ? 467 ASP A O   1 
ATOM 2701 C CB  . ASP C 3 135 ? 160.255 189.150 144.959 1.00 49.59  ? 467 ASP A CB  1 
ATOM 2702 C CG  . ASP C 3 135 ? 159.422 190.341 144.519 1.00 49.59  ? 467 ASP A CG  1 
ATOM 2703 O OD1 . ASP C 3 135 ? 158.272 190.144 144.075 1.00 49.59  ? 467 ASP A OD1 1 
ATOM 2704 O OD2 . ASP C 3 135 ? 159.922 191.480 144.621 1.00 49.59  ? 467 ASP A OD2 1 
ATOM 2705 N N   . ILE C 3 136 ? 158.391 186.455 143.181 1.00 49.17  ? 468 ILE A N   1 
ATOM 2706 C CA  . ILE C 3 136 ? 158.044 186.000 141.841 1.00 49.17  ? 468 ILE A CA  1 
ATOM 2707 C C   . ILE C 3 136 ? 157.209 187.032 141.093 1.00 49.17  ? 468 ILE A C   1 
ATOM 2708 O O   . ILE C 3 136 ? 157.164 187.011 139.858 1.00 49.17  ? 468 ILE A O   1 
ATOM 2709 C CB  . ILE C 3 136 ? 157.317 184.643 141.919 1.00 49.17  ? 468 ILE A CB  1 
ATOM 2710 C CG1 . ILE C 3 136 ? 157.170 184.018 140.529 1.00 49.17  ? 468 ILE A CG1 1 
ATOM 2711 C CG2 . ILE C 3 136 ? 155.959 184.798 142.588 1.00 49.17  ? 468 ILE A CG2 1 
ATOM 2712 C CD1 . ILE C 3 136 ? 156.762 182.564 140.554 1.00 49.17  ? 468 ILE A CD1 1 
ATOM 2713 N N   . SER C 3 137 ? 156.554 187.944 141.810 1.00 54.87  ? 469 SER A N   1 
ATOM 2714 C CA  . SER C 3 137 ? 155.724 188.955 141.168 1.00 54.87  ? 469 SER A CA  1 
ATOM 2715 C C   . SER C 3 137 ? 156.569 189.854 140.274 1.00 54.87  ? 469 SER A C   1 
ATOM 2716 O O   . SER C 3 137 ? 157.637 190.324 140.674 1.00 54.87  ? 469 SER A O   1 
ATOM 2717 C CB  . SER C 3 137 ? 155.003 189.792 142.223 1.00 54.87  ? 469 SER A CB  1 
ATOM 2718 O OG  . SER C 3 137 ? 155.840 190.826 142.711 1.00 54.87  ? 469 SER A OG  1 
ATOM 2719 N N   . THR C 3 138 ? 156.083 190.093 139.061 1.00 56.18  ? 470 THR A N   1 
ATOM 2720 C CA  . THR C 3 138 ? 156.773 190.918 138.072 1.00 56.18  ? 470 THR A CA  1 
ATOM 2721 C C   . THR C 3 138 ? 155.964 192.199 137.841 1.00 56.18  ? 470 THR A C   1 
ATOM 2722 O O   . THR C 3 138 ? 155.094 192.272 136.971 1.00 56.18  ? 470 THR A O   1 
ATOM 2723 C CB  . THR C 3 138 ? 157.036 190.105 136.779 1.00 56.18  ? 470 THR A CB  1 
ATOM 2724 O OG1 . THR C 3 138 ? 157.848 190.864 135.874 1.00 56.18  ? 470 THR A OG1 1 
ATOM 2725 C CG2 . THR C 3 138 ? 155.751 189.600 136.105 1.00 56.18  ? 470 THR A CG2 1 
ATOM 2726 N N   . GLU C 3 139 ? 156.261 193.218 138.639 1.00 60.90  ? 471 GLU A N   1 
ATOM 2727 C CA  . GLU C 3 139 ? 155.604 194.512 138.544 1.00 60.90  ? 471 GLU A CA  1 
ATOM 2728 C C   . GLU C 3 139 ? 156.591 195.550 138.029 1.00 60.90  ? 471 GLU A C   1 
ATOM 2729 O O   . GLU C 3 139 ? 157.779 195.510 138.363 1.00 60.90  ? 471 GLU A O   1 
ATOM 2730 C CB  . GLU C 3 139 ? 155.039 194.949 139.901 1.00 60.90  ? 471 GLU A CB  1 
ATOM 2731 C CG  . GLU C 3 139 ? 153.844 194.136 140.439 1.00 60.90  ? 471 GLU A CG  1 
ATOM 2732 C CD  . GLU C 3 139 ? 152.740 193.824 139.423 1.00 60.90  ? 471 GLU A CD  1 
ATOM 2733 O OE1 . GLU C 3 139 ? 151.862 193.002 139.760 1.00 60.90  ? 471 GLU A OE1 1 
ATOM 2734 O OE2 . GLU C 3 139 ? 152.692 194.428 138.330 1.00 60.90  ? 471 GLU A OE2 1 
ATOM 2735 N N   . ILE C 3 140 ? 156.086 196.482 137.218 1.00 59.15  ? 472 ILE A N   1 
ATOM 2736 C CA  . ILE C 3 140 ? 156.948 197.467 136.579 1.00 59.15  ? 472 ILE A CA  1 
ATOM 2737 C C   . ILE C 3 140 ? 157.566 198.371 137.633 1.00 59.15  ? 472 ILE A C   1 
ATOM 2738 O O   . ILE C 3 140 ? 156.863 198.959 138.464 1.00 59.15  ? 472 ILE A O   1 
ATOM 2739 C CB  . ILE C 3 140 ? 156.153 198.276 135.546 1.00 59.15  ? 472 ILE A CB  1 
ATOM 2740 C CG1 . ILE C 3 140 ? 155.567 197.345 134.486 1.00 59.15  ? 472 ILE A CG1 1 
ATOM 2741 C CG2 . ILE C 3 140 ? 157.035 199.330 134.902 1.00 59.15  ? 472 ILE A CG2 1 
ATOM 2742 C CD1 . ILE C 3 140 ? 156.610 196.584 133.711 1.00 59.15  ? 472 ILE A CD1 1 
ATOM 2743 N N   . TYR C 3 141 ? 158.890 198.484 137.604 1.00 62.71  ? 473 TYR A N   1 
ATOM 2744 C CA  . TYR C 3 141 ? 159.591 199.352 138.538 1.00 62.71  ? 473 TYR A CA  1 
ATOM 2745 C C   . TYR C 3 141 ? 159.375 200.810 138.159 1.00 62.71  ? 473 TYR A C   1 
ATOM 2746 O O   . TYR C 3 141 ? 159.591 201.202 137.009 1.00 62.71  ? 473 TYR A O   1 
ATOM 2747 C CB  . TYR C 3 141 ? 161.082 199.024 138.542 1.00 62.71  ? 473 TYR A CB  1 
ATOM 2748 C CG  . TYR C 3 141 ? 161.868 199.750 139.608 1.00 62.71  ? 473 TYR A CG  1 
ATOM 2749 C CD1 . TYR C 3 141 ? 161.413 199.805 140.916 1.00 62.71  ? 473 TYR A CD1 1 
ATOM 2750 C CD2 . TYR C 3 141 ? 163.059 200.391 139.301 1.00 62.71  ? 473 TYR A CD2 1 
ATOM 2751 C CE1 . TYR C 3 141 ? 162.129 200.469 141.892 1.00 62.71  ? 473 TYR A CE1 1 
ATOM 2752 C CE2 . TYR C 3 141 ? 163.782 201.057 140.270 1.00 62.71  ? 473 TYR A CE2 1 
ATOM 2753 C CZ  . TYR C 3 141 ? 163.312 201.094 141.563 1.00 62.71  ? 473 TYR A CZ  1 
ATOM 2754 O OH  . TYR C 3 141 ? 164.027 201.758 142.531 1.00 62.71  ? 473 TYR A OH  1 
ATOM 2755 N N   . GLN C 3 142 ? 158.951 201.617 139.131 1.00 67.46  ? 474 GLN A N   1 
ATOM 2756 C CA  . GLN C 3 142 ? 158.724 203.045 138.918 1.00 67.46  ? 474 GLN A CA  1 
ATOM 2757 C C   . GLN C 3 142 ? 159.967 203.795 139.389 1.00 67.46  ? 474 GLN A C   1 
ATOM 2758 O O   . GLN C 3 142 ? 160.004 204.388 140.467 1.00 67.46  ? 474 GLN A O   1 
ATOM 2759 C CB  . GLN C 3 142 ? 157.467 203.505 139.648 1.00 67.46  ? 474 GLN A CB  1 
ATOM 2760 N N   . ALA C 3 143 ? 161.008 203.753 138.553 1.00 65.63  ? 475 ALA A N   1 
ATOM 2761 C CA  . ALA C 3 143 ? 162.268 204.399 138.906 1.00 65.63  ? 475 ALA A CA  1 
ATOM 2762 C C   . ALA C 3 143 ? 162.108 205.909 139.011 1.00 65.63  ? 475 ALA A C   1 
ATOM 2763 O O   . ALA C 3 143 ? 162.647 206.536 139.930 1.00 65.63  ? 475 ALA A O   1 
ATOM 2764 C CB  . ALA C 3 143 ? 163.344 204.043 137.882 1.00 65.63  ? 475 ALA A CB  1 
ATOM 2765 N N   . GLY C 3 144 ? 161.369 206.511 138.082 1.00 70.40  ? 476 GLY A N   1 
ATOM 2766 C CA  . GLY C 3 144 ? 161.177 207.945 138.057 1.00 70.40  ? 476 GLY A CA  1 
ATOM 2767 C C   . GLY C 3 144 ? 160.039 208.392 138.954 1.00 70.40  ? 476 GLY A C   1 
ATOM 2768 O O   . GLY C 3 144 ? 159.488 207.629 139.749 1.00 70.40  ? 476 GLY A O   1 
ATOM 2769 N N   . SER C 3 145 ? 159.687 209.668 138.813 1.00 78.13  ? 477 SER A N   1 
ATOM 2770 C CA  . SER C 3 145 ? 158.626 210.278 139.600 1.00 78.13  ? 477 SER A CA  1 
ATOM 2771 C C   . SER C 3 145 ? 157.269 210.206 138.912 1.00 78.13  ? 477 SER A C   1 
ATOM 2772 O O   . SER C 3 145 ? 156.281 210.702 139.462 1.00 78.13  ? 477 SER A O   1 
ATOM 2773 C CB  . SER C 3 145 ? 158.975 211.734 139.915 1.00 78.13  ? 477 SER A CB  1 
ATOM 2774 O OG  . SER C 3 145 ? 160.241 211.830 140.542 1.00 78.13  ? 477 SER A OG  1 
ATOM 2775 N N   . THR C 3 146 ? 157.196 209.601 137.727 1.00 84.53  ? 478 THR A N   1 
ATOM 2776 C CA  . THR C 3 146 ? 155.932 209.479 137.018 1.00 84.53  ? 478 THR A CA  1 
ATOM 2777 C C   . THR C 3 146 ? 155.307 208.119 137.296 1.00 84.53  ? 478 THR A C   1 
ATOM 2778 O O   . THR C 3 146 ? 155.913 207.087 136.968 1.00 84.53  ? 478 THR A O   1 
ATOM 2779 C CB  . THR C 3 146 ? 156.126 209.695 135.513 1.00 84.53  ? 478 THR A CB  1 
ATOM 2780 O OG1 . THR C 3 146 ? 154.887 209.473 134.825 1.00 84.53  ? 478 THR A OG1 1 
ATOM 2781 C CG2 . THR C 3 146 ? 157.230 208.803 134.934 1.00 84.53  ? 478 THR A CG2 1 
ATOM 2782 N N   . PRO C 3 147 ? 154.134 208.059 137.923 1.00 88.45  ? 479 PRO A N   1 
ATOM 2783 C CA  . PRO C 3 147 ? 153.486 206.761 138.149 1.00 88.45  ? 479 PRO A CA  1 
ATOM 2784 C C   . PRO C 3 147 ? 152.817 206.232 136.892 1.00 88.45  ? 479 PRO A C   1 
ATOM 2785 O O   . PRO C 3 147 ? 151.604 206.385 136.721 1.00 88.45  ? 479 PRO A O   1 
ATOM 2786 C CB  . PRO C 3 147 ? 152.453 207.066 139.246 1.00 88.45  ? 479 PRO A CB  1 
ATOM 2787 C CG  . PRO C 3 147 ? 152.816 208.432 139.778 1.00 88.45  ? 479 PRO A CG  1 
ATOM 2788 C CD  . PRO C 3 147 ? 153.448 209.148 138.633 1.00 88.45  ? 479 PRO A CD  1 
ATOM 2789 N N   . CYS C 3 148 ? 153.599 205.618 136.001 1.00 86.25  ? 480 CYS A N   1 
ATOM 2790 C CA  . CYS C 3 148 ? 153.032 205.087 134.766 1.00 86.25  ? 480 CYS A CA  1 
ATOM 2791 C C   . CYS C 3 148 ? 152.025 203.980 135.056 1.00 86.25  ? 480 CYS A C   1 
ATOM 2792 O O   . CYS C 3 148 ? 150.883 204.028 134.585 1.00 86.25  ? 480 CYS A O   1 
ATOM 2793 C CB  . CYS C 3 148 ? 154.148 204.580 133.850 1.00 86.25  ? 480 CYS A CB  1 
ATOM 2794 S SG  . CYS C 3 148 ? 155.257 203.361 134.596 1.00 86.25  ? 480 CYS A SG  1 
ATOM 2795 N N   . ASN C 3 149 ? 152.429 202.985 135.843 1.00 86.16  ? 481 ASN A N   1 
ATOM 2796 C CA  . ASN C 3 149 ? 151.571 201.866 136.231 1.00 86.16  ? 481 ASN A CA  1 
ATOM 2797 C C   . ASN C 3 149 ? 150.948 201.201 135.003 1.00 86.16  ? 481 ASN A C   1 
ATOM 2798 O O   . ASN C 3 149 ? 149.730 201.167 134.824 1.00 86.16  ? 481 ASN A O   1 
ATOM 2799 C CB  . ASN C 3 149 ? 150.493 202.323 137.218 1.00 86.16  ? 481 ASN A CB  1 
ATOM 2800 N N   . GLY C 3 150 ? 151.818 200.671 134.149 1.00 78.20  ? 482 GLY A N   1 
ATOM 2801 C CA  . GLY C 3 150 ? 151.371 200.052 132.918 1.00 78.20  ? 482 GLY A CA  1 
ATOM 2802 C C   . GLY C 3 150 ? 152.512 199.593 132.035 1.00 78.20  ? 482 GLY A C   1 
ATOM 2803 O O   . GLY C 3 150 ? 153.444 198.935 132.506 1.00 78.20  ? 482 GLY A O   1 
ATOM 2804 N N   . VAL C 3 151 ? 152.440 199.929 130.745 1.00 73.44  ? 483 VAL A N   1 
ATOM 2805 C CA  . VAL C 3 151 ? 153.486 199.533 129.812 1.00 73.44  ? 483 VAL A CA  1 
ATOM 2806 C C   . VAL C 3 151 ? 154.805 200.179 130.211 1.00 73.44  ? 483 VAL A C   1 
ATOM 2807 O O   . VAL C 3 151 ? 154.858 201.362 130.573 1.00 73.44  ? 483 VAL A O   1 
ATOM 2808 C CB  . VAL C 3 151 ? 153.091 199.911 128.375 1.00 73.44  ? 483 VAL A CB  1 
ATOM 2809 C CG1 . VAL C 3 151 ? 154.100 199.358 127.380 1.00 73.44  ? 483 VAL A CG1 1 
ATOM 2810 C CG2 . VAL C 3 151 ? 151.692 199.406 128.061 1.00 73.44  ? 483 VAL A CG2 1 
ATOM 2811 N N   . GLU C 3 152 ? 155.878 199.394 130.157 1.00 68.01  ? 484 GLU A N   1 
ATOM 2812 C CA  . GLU C 3 152 ? 157.193 199.896 130.528 1.00 68.01  ? 484 GLU A CA  1 
ATOM 2813 C C   . GLU C 3 152 ? 157.647 200.979 129.556 1.00 68.01  ? 484 GLU A C   1 
ATOM 2814 O O   . GLU C 3 152 ? 157.306 200.958 128.370 1.00 68.01  ? 484 GLU A O   1 
ATOM 2815 C CB  . GLU C 3 152 ? 158.206 198.750 130.563 1.00 68.01  ? 484 GLU A CB  1 
ATOM 2816 C CG  . GLU C 3 152 ? 158.620 198.231 129.197 1.00 68.01  ? 484 GLU A CG  1 
ATOM 2817 C CD  . GLU C 3 152 ? 157.764 197.071 128.730 1.00 68.01  ? 484 GLU A CD  1 
ATOM 2818 O OE1 . GLU C 3 152 ? 156.523 197.168 128.827 1.00 68.01  ? 484 GLU A OE1 1 
ATOM 2819 O OE2 . GLU C 3 152 ? 158.333 196.062 128.264 1.00 68.01  ? 484 GLU A OE2 1 
ATOM 2820 N N   . GLY C 3 153 ? 158.410 201.939 130.071 1.00 62.81  ? 485 GLY A N   1 
ATOM 2821 C CA  . GLY C 3 153 ? 158.881 203.044 129.261 1.00 62.81  ? 485 GLY A CA  1 
ATOM 2822 C C   . GLY C 3 153 ? 159.937 203.882 129.950 1.00 62.81  ? 485 GLY A C   1 
ATOM 2823 O O   . GLY C 3 153 ? 160.836 203.345 130.604 1.00 62.81  ? 485 GLY A O   1 
ATOM 2824 N N   . PHE C 3 154 ? 159.840 205.201 129.804 1.00 60.59  ? 486 PHE A N   1 
ATOM 2825 C CA  . PHE C 3 154 ? 160.790 206.105 130.438 1.00 60.59  ? 486 PHE A CA  1 
ATOM 2826 C C   . PHE C 3 154 ? 160.726 205.964 131.952 1.00 60.59  ? 486 PHE A C   1 
ATOM 2827 O O   . PHE C 3 154 ? 159.695 206.253 132.568 1.00 60.59  ? 486 PHE A O   1 
ATOM 2828 C CB  . PHE C 3 154 ? 160.497 207.545 130.024 1.00 60.59  ? 486 PHE A CB  1 
ATOM 2829 C CG  . PHE C 3 154 ? 161.590 208.509 130.375 1.00 60.59  ? 486 PHE A CG  1 
ATOM 2830 C CD1 . PHE C 3 154 ? 162.828 208.422 129.765 1.00 60.59  ? 486 PHE A CD1 1 
ATOM 2831 C CD2 . PHE C 3 154 ? 161.380 209.502 131.316 1.00 60.59  ? 486 PHE A CD2 1 
ATOM 2832 C CE1 . PHE C 3 154 ? 163.835 209.306 130.085 1.00 60.59  ? 486 PHE A CE1 1 
ATOM 2833 C CE2 . PHE C 3 154 ? 162.383 210.389 131.641 1.00 60.59  ? 486 PHE A CE2 1 
ATOM 2834 C CZ  . PHE C 3 154 ? 163.613 210.291 131.024 1.00 60.59  ? 486 PHE A CZ  1 
ATOM 2835 N N   . ASN C 3 155 ? 161.826 205.506 132.545 1.00 63.45  ? 487 ASN A N   1 
ATOM 2836 C CA  . ASN C 3 155 ? 161.963 205.283 133.982 1.00 63.45  ? 487 ASN A CA  1 
ATOM 2837 C C   . ASN C 3 155 ? 160.975 204.255 134.519 1.00 63.45  ? 487 ASN A C   1 
ATOM 2838 O O   . ASN C 3 155 ? 160.846 204.106 135.740 1.00 63.45  ? 487 ASN A O   1 
ATOM 2839 C CB  . ASN C 3 155 ? 161.832 206.593 134.769 1.00 63.45  ? 487 ASN A CB  1 
ATOM 2840 C CG  . ASN C 3 155 ? 163.080 207.447 134.691 1.00 63.45  ? 487 ASN A CG  1 
ATOM 2841 O OD1 . ASN C 3 155 ? 164.189 206.933 134.546 1.00 63.45  ? 487 ASN A OD1 1 
ATOM 2842 N ND2 . ASN C 3 155 ? 162.907 208.759 134.787 1.00 63.45  ? 487 ASN A ND2 1 
ATOM 2843 N N   . CYS C 3 156 ? 160.273 203.542 133.644 1.00 67.30  ? 488 CYS A N   1 
ATOM 2844 C CA  . CYS C 3 156 ? 159.396 202.439 134.025 1.00 67.30  ? 488 CYS A CA  1 
ATOM 2845 C C   . CYS C 3 156 ? 160.059 201.168 133.503 1.00 67.30  ? 488 CYS A C   1 
ATOM 2846 O O   . CYS C 3 156 ? 159.889 200.791 132.343 1.00 67.30  ? 488 CYS A O   1 
ATOM 2847 C CB  . CYS C 3 156 ? 157.989 202.627 133.466 1.00 67.30  ? 488 CYS A CB  1 
ATOM 2848 S SG  . CYS C 3 156 ? 157.114 204.055 134.152 1.00 67.30  ? 488 CYS A SG  1 
ATOM 2849 N N   . TYR C 3 157 ? 160.823 200.514 134.370 1.00 56.99  ? 489 TYR A N   1 
ATOM 2850 C CA  . TYR C 3 157 ? 161.685 199.409 133.982 1.00 56.99  ? 489 TYR A CA  1 
ATOM 2851 C C   . TYR C 3 157 ? 161.027 198.075 134.300 1.00 56.99  ? 489 TYR A C   1 
ATOM 2852 O O   . TYR C 3 157 ? 160.418 197.907 135.360 1.00 56.99  ? 489 TYR A O   1 
ATOM 2853 C CB  . TYR C 3 157 ? 163.028 199.494 134.707 1.00 56.99  ? 489 TYR A CB  1 
ATOM 2854 C CG  . TYR C 3 157 ? 163.869 200.688 134.328 1.00 56.99  ? 489 TYR A CG  1 
ATOM 2855 C CD1 . TYR C 3 157 ? 164.108 201.003 133.000 1.00 56.99  ? 489 TYR A CD1 1 
ATOM 2856 C CD2 . TYR C 3 157 ? 164.427 201.500 135.305 1.00 56.99  ? 489 TYR A CD2 1 
ATOM 2857 C CE1 . TYR C 3 157 ? 164.878 202.095 132.657 1.00 56.99  ? 489 TYR A CE1 1 
ATOM 2858 C CE2 . TYR C 3 157 ? 165.197 202.591 134.972 1.00 56.99  ? 489 TYR A CE2 1 
ATOM 2859 C CZ  . TYR C 3 157 ? 165.420 202.885 133.647 1.00 56.99  ? 489 TYR A CZ  1 
ATOM 2860 O OH  . TYR C 3 157 ? 166.188 203.976 133.316 1.00 56.99  ? 489 TYR A OH  1 
ATOM 2861 N N   . PHE C 3 158 ? 161.153 197.132 133.379 1.00 51.42  ? 490 PHE A N   1 
ATOM 2862 C CA  . PHE C 3 158 ? 160.773 195.758 133.670 1.00 51.42  ? 490 PHE A CA  1 
ATOM 2863 C C   . PHE C 3 158 ? 161.830 195.134 134.574 1.00 51.42  ? 490 PHE A C   1 
ATOM 2864 O O   . PHE C 3 158 ? 163.015 195.133 134.222 1.00 51.42  ? 490 PHE A O   1 
ATOM 2865 C CB  . PHE C 3 158 ? 160.635 194.960 132.377 1.00 51.42  ? 490 PHE A CB  1 
ATOM 2866 C CG  . PHE C 3 158 ? 159.882 193.672 132.534 1.00 51.42  ? 490 PHE A CG  1 
ATOM 2867 C CD1 . PHE C 3 158 ? 158.595 193.665 133.038 1.00 51.42  ? 490 PHE A CD1 1 
ATOM 2868 C CD2 . PHE C 3 158 ? 160.459 192.470 132.166 1.00 51.42  ? 490 PHE A CD2 1 
ATOM 2869 C CE1 . PHE C 3 158 ? 157.899 192.482 133.178 1.00 51.42  ? 490 PHE A CE1 1 
ATOM 2870 C CE2 . PHE C 3 158 ? 159.769 191.284 132.304 1.00 51.42  ? 490 PHE A CE2 1 
ATOM 2871 C CZ  . PHE C 3 158 ? 158.487 191.290 132.811 1.00 51.42  ? 490 PHE A CZ  1 
ATOM 2872 N N   . PRO C 3 159 ? 161.454 194.601 135.738 1.00 49.94  ? 491 PRO A N   1 
ATOM 2873 C CA  . PRO C 3 159 ? 162.479 194.147 136.688 1.00 49.94  ? 491 PRO A CA  1 
ATOM 2874 C C   . PRO C 3 159 ? 163.178 192.867 136.266 1.00 49.94  ? 491 PRO A C   1 
ATOM 2875 O O   . PRO C 3 159 ? 164.331 192.652 136.658 1.00 49.94  ? 491 PRO A O   1 
ATOM 2876 C CB  . PRO C 3 159 ? 161.689 193.958 137.987 1.00 49.94  ? 491 PRO A CB  1 
ATOM 2877 C CG  . PRO C 3 159 ? 160.313 193.632 137.537 1.00 49.94  ? 491 PRO A CG  1 
ATOM 2878 C CD  . PRO C 3 159 ? 160.090 194.321 136.215 1.00 49.94  ? 491 PRO A CD  1 
ATOM 2879 N N   . LEU C 3 160 ? 162.528 192.015 135.480 1.00 50.77  ? 492 LEU A N   1 
ATOM 2880 C CA  . LEU C 3 160 ? 163.099 190.732 135.090 1.00 50.77  ? 492 LEU A CA  1 
ATOM 2881 C C   . LEU C 3 160 ? 163.895 190.896 133.802 1.00 50.77  ? 492 LEU A C   1 
ATOM 2882 O O   . LEU C 3 160 ? 163.342 191.285 132.768 1.00 50.77  ? 492 LEU A O   1 
ATOM 2883 C CB  . LEU C 3 160 ? 162.004 189.682 134.909 1.00 50.77  ? 492 LEU A CB  1 
ATOM 2884 C CG  . LEU C 3 160 ? 161.607 188.823 136.113 1.00 50.77  ? 492 LEU A CG  1 
ATOM 2885 C CD1 . LEU C 3 160 ? 161.486 189.648 137.380 1.00 50.77  ? 492 LEU A CD1 1 
ATOM 2886 C CD2 . LEU C 3 160 ? 160.309 188.087 135.829 1.00 50.77  ? 492 LEU A CD2 1 
ATOM 2887 N N   . GLN C 3 161 ? 165.189 190.594 133.864 1.00 49.12  ? 493 GLN A N   1 
ATOM 2888 C CA  . GLN C 3 161 ? 166.056 190.622 132.696 1.00 49.12  ? 493 GLN A CA  1 
ATOM 2889 C C   . GLN C 3 161 ? 166.815 189.309 132.597 1.00 49.12  ? 493 GLN A C   1 
ATOM 2890 O O   . GLN C 3 161 ? 167.034 188.623 133.597 1.00 49.12  ? 493 GLN A O   1 
ATOM 2891 C CB  . GLN C 3 161 ? 167.036 191.799 132.744 1.00 49.12  ? 493 GLN A CB  1 
ATOM 2892 C CG  . GLN C 3 161 ? 166.571 193.015 131.960 1.00 49.12  ? 493 GLN A CG  1 
ATOM 2893 C CD  . GLN C 3 161 ? 166.778 192.857 130.467 1.00 49.12  ? 493 GLN A CD  1 
ATOM 2894 O OE1 . GLN C 3 161 ? 167.906 192.694 130.000 1.00 49.12  ? 493 GLN A OE1 1 
ATOM 2895 N NE2 . GLN C 3 161 ? 165.689 192.902 129.709 1.00 49.12  ? 493 GLN A NE2 1 
ATOM 2896 N N   . SER C 3 162 ? 167.218 188.968 131.378 1.00 44.76  ? 494 SER A N   1 
ATOM 2897 C CA  . SER C 3 162 ? 167.820 187.674 131.098 1.00 44.76  ? 494 SER A CA  1 
ATOM 2898 C C   . SER C 3 162 ? 169.336 187.733 131.221 1.00 44.76  ? 494 SER A C   1 
ATOM 2899 O O   . SER C 3 162 ? 169.965 188.730 130.857 1.00 44.76  ? 494 SER A O   1 
ATOM 2900 C CB  . SER C 3 162 ? 167.433 187.199 129.697 1.00 44.76  ? 494 SER A CB  1 
ATOM 2901 O OG  . SER C 3 162 ? 168.261 186.127 129.282 1.00 44.76  ? 494 SER A OG  1 
ATOM 2902 N N   . TYR C 3 163 ? 169.916 186.652 131.748 1.00 42.93  ? 495 TYR A N   1 
ATOM 2903 C CA  . TYR C 3 163 ? 171.369 186.515 131.772 1.00 42.93  ? 495 TYR A CA  1 
ATOM 2904 C C   . TYR C 3 163 ? 171.949 186.482 130.364 1.00 42.93  ? 495 TYR A C   1 
ATOM 2905 O O   . TYR C 3 163 ? 172.951 187.146 130.077 1.00 42.93  ? 495 TYR A O   1 
ATOM 2906 C CB  . TYR C 3 163 ? 171.760 185.253 132.540 1.00 42.93  ? 495 TYR A CB  1 
ATOM 2907 C CG  . TYR C 3 163 ? 171.672 185.373 134.042 1.00 42.93  ? 495 TYR A CG  1 
ATOM 2908 C CD1 . TYR C 3 163 ? 172.078 186.530 134.687 1.00 42.93  ? 495 TYR A CD1 1 
ATOM 2909 C CD2 . TYR C 3 163 ? 171.172 184.336 134.813 1.00 42.93  ? 495 TYR A CD2 1 
ATOM 2910 C CE1 . TYR C 3 163 ? 172.012 186.641 136.059 1.00 42.93  ? 495 TYR A CE1 1 
ATOM 2911 C CE2 . TYR C 3 163 ? 171.094 184.442 136.185 1.00 42.93  ? 495 TYR A CE2 1 
ATOM 2912 C CZ  . TYR C 3 163 ? 171.513 185.598 136.802 1.00 42.93  ? 495 TYR A CZ  1 
ATOM 2913 O OH  . TYR C 3 163 ? 171.435 185.709 138.168 1.00 42.93  ? 495 TYR A OH  1 
ATOM 2914 N N   . GLY C 3 164 ? 171.334 185.712 129.471 1.00 49.03  ? 496 GLY A N   1 
ATOM 2915 C CA  . GLY C 3 164 ? 171.875 185.541 128.138 1.00 49.03  ? 496 GLY A CA  1 
ATOM 2916 C C   . GLY C 3 164 ? 173.192 184.792 128.140 1.00 49.03  ? 496 GLY A C   1 
ATOM 2917 O O   . GLY C 3 164 ? 174.234 185.349 127.783 1.00 49.03  ? 496 GLY A O   1 
ATOM 2918 N N   . PHE C 3 165 ? 173.155 183.525 128.544 1.00 47.72  ? 497 PHE A N   1 
ATOM 2919 C CA  . PHE C 3 165 ? 174.359 182.713 128.625 1.00 47.72  ? 497 PHE A CA  1 
ATOM 2920 C C   . PHE C 3 165 ? 174.749 182.185 127.251 1.00 47.72  ? 497 PHE A C   1 
ATOM 2921 O O   . PHE C 3 165 ? 173.895 181.763 126.466 1.00 47.72  ? 497 PHE A O   1 
ATOM 2922 C CB  . PHE C 3 165 ? 174.143 181.543 129.583 1.00 47.72  ? 497 PHE A CB  1 
ATOM 2923 C CG  . PHE C 3 165 ? 174.027 181.950 131.021 1.00 47.72  ? 497 PHE A CG  1 
ATOM 2924 C CD1 . PHE C 3 165 ? 174.885 182.890 131.558 1.00 47.72  ? 497 PHE A CD1 1 
ATOM 2925 C CD2 . PHE C 3 165 ? 173.059 181.391 131.835 1.00 47.72  ? 497 PHE A CD2 1 
ATOM 2926 C CE1 . PHE C 3 165 ? 174.781 183.263 132.880 1.00 47.72  ? 497 PHE A CE1 1 
ATOM 2927 C CE2 . PHE C 3 165 ? 172.951 181.762 133.156 1.00 47.72  ? 497 PHE A CE2 1 
ATOM 2928 C CZ  . PHE C 3 165 ? 173.816 182.696 133.680 1.00 47.72  ? 497 PHE A CZ  1 
ATOM 2929 N N   . GLN C 3 166 ? 176.047 182.201 126.968 1.00 56.58  ? 498 GLN A N   1 
ATOM 2930 C CA  . GLN C 3 166 ? 176.580 181.685 125.718 1.00 56.58  ? 498 GLN A CA  1 
ATOM 2931 C C   . GLN C 3 166 ? 177.729 180.729 125.997 1.00 56.58  ? 498 GLN A C   1 
ATOM 2932 O O   . GLN C 3 166 ? 178.439 180.879 126.997 1.00 56.58  ? 498 GLN A O   1 
ATOM 2933 C CB  . GLN C 3 166 ? 177.070 182.821 124.807 1.00 56.58  ? 498 GLN A CB  1 
ATOM 2934 C CG  . GLN C 3 166 ? 176.013 183.863 124.481 1.00 56.58  ? 498 GLN A CG  1 
ATOM 2935 C CD  . GLN C 3 166 ? 176.583 185.264 124.397 1.00 56.58  ? 498 GLN A CD  1 
ATOM 2936 O OE1 . GLN C 3 166 ? 177.787 185.447 124.221 1.00 56.58  ? 498 GLN A OE1 1 
ATOM 2937 N NE2 . GLN C 3 166 ? 175.718 186.263 124.523 1.00 56.58  ? 498 GLN A NE2 1 
ATOM 2938 N N   . PRO C 3 167 ? 177.928 179.730 125.134 1.00 57.99  ? 499 PRO A N   1 
ATOM 2939 C CA  . PRO C 3 167 ? 179.063 178.813 125.329 1.00 57.99  ? 499 PRO A CA  1 
ATOM 2940 C C   . PRO C 3 167 ? 180.412 179.506 125.291 1.00 57.99  ? 499 PRO A C   1 
ATOM 2941 O O   . PRO C 3 167 ? 181.341 179.075 125.985 1.00 57.99  ? 499 PRO A O   1 
ATOM 2942 C CB  . PRO C 3 167 ? 178.910 177.814 124.174 1.00 57.99  ? 499 PRO A CB  1 
ATOM 2943 C CG  . PRO C 3 167 ? 177.479 177.914 123.762 1.00 57.99  ? 499 PRO A CG  1 
ATOM 2944 C CD  . PRO C 3 167 ? 177.095 179.343 123.985 1.00 57.99  ? 499 PRO A CD  1 
ATOM 2945 N N   . THR C 3 168 ? 180.549 180.570 124.503 1.00 64.14  ? 500 THR A N   1 
ATOM 2946 C CA  . THR C 3 168 ? 181.813 181.284 124.381 1.00 64.14  ? 500 THR A CA  1 
ATOM 2947 C C   . THR C 3 168 ? 182.023 182.310 125.485 1.00 64.14  ? 500 THR A C   1 
ATOM 2948 O O   . THR C 3 168 ? 183.044 183.007 125.473 1.00 64.14  ? 500 THR A O   1 
ATOM 2949 C CB  . THR C 3 168 ? 181.900 181.974 123.017 1.00 64.14  ? 500 THR A CB  1 
ATOM 2950 O OG1 . THR C 3 168 ? 180.840 182.930 122.895 1.00 64.14  ? 500 THR A OG1 1 
ATOM 2951 C CG2 . THR C 3 168 ? 181.786 180.952 121.896 1.00 64.14  ? 500 THR A CG2 1 
ATOM 2952 N N   . ASN C 3 169 ? 181.091 182.424 126.425 1.00 56.26  ? 501 ASN A N   1 
ATOM 2953 C CA  . ASN C 3 169 ? 181.231 183.370 127.519 1.00 56.26  ? 501 ASN A CA  1 
ATOM 2954 C C   . ASN C 3 169 ? 182.389 182.968 128.429 1.00 56.26  ? 501 ASN A C   1 
ATOM 2955 O O   . ASN C 3 169 ? 182.805 181.807 128.478 1.00 56.26  ? 501 ASN A O   1 
ATOM 2956 C CB  . ASN C 3 169 ? 179.933 183.452 128.323 1.00 56.26  ? 501 ASN A CB  1 
ATOM 2957 C CG  . ASN C 3 169 ? 179.879 184.669 129.222 1.00 56.26  ? 501 ASN A CG  1 
ATOM 2958 O OD1 . ASN C 3 169 ? 180.836 185.440 129.303 1.00 56.26  ? 501 ASN A OD1 1 
ATOM 2959 N ND2 . ASN C 3 169 ? 178.756 184.849 129.907 1.00 56.26  ? 501 ASN A ND2 1 
ATOM 2960 N N   . GLY C 3 170 ? 182.913 183.954 129.153 1.00 52.80  ? 502 GLY A N   1 
ATOM 2961 C CA  . GLY C 3 170 ? 184.020 183.701 130.049 1.00 52.80  ? 502 GLY A CA  1 
ATOM 2962 C C   . GLY C 3 170 ? 183.631 182.810 131.212 1.00 52.80  ? 502 GLY A C   1 
ATOM 2963 O O   . GLY C 3 170 ? 182.459 182.655 131.557 1.00 52.80  ? 502 GLY A O   1 
ATOM 2964 N N   . VAL C 3 171 ? 184.651 182.204 131.822 1.00 48.76  ? 503 VAL A N   1 
ATOM 2965 C CA  . VAL C 3 171 ? 184.418 181.294 132.941 1.00 48.76  ? 503 VAL A CA  1 
ATOM 2966 C C   . VAL C 3 171 ? 183.762 182.033 134.100 1.00 48.76  ? 503 VAL A C   1 
ATOM 2967 O O   . VAL C 3 171 ? 182.828 181.525 134.732 1.00 48.76  ? 503 VAL A O   1 
ATOM 2968 C CB  . VAL C 3 171 ? 185.737 180.624 133.368 1.00 48.76  ? 503 VAL A CB  1 
ATOM 2969 C CG1 . VAL C 3 171 ? 185.585 179.955 134.725 1.00 48.76  ? 503 VAL A CG1 1 
ATOM 2970 C CG2 . VAL C 3 171 ? 186.183 179.618 132.319 1.00 48.76  ? 503 VAL A CG2 1 
ATOM 2971 N N   . GLY C 3 172 ? 184.228 183.249 134.388 1.00 50.78  ? 504 GLY A N   1 
ATOM 2972 C CA  . GLY C 3 172 ? 183.661 184.022 135.477 1.00 50.78  ? 504 GLY A CA  1 
ATOM 2973 C C   . GLY C 3 172 ? 182.244 184.495 135.233 1.00 50.78  ? 504 GLY A C   1 
ATOM 2974 O O   . GLY C 3 172 ? 181.585 184.950 136.172 1.00 50.78  ? 504 GLY A O   1 
ATOM 2975 N N   . TYR C 3 173 ? 181.761 184.403 133.997 1.00 48.75  ? 505 TYR A N   1 
ATOM 2976 C CA  . TYR C 3 173 ? 180.407 184.808 133.641 1.00 48.75  ? 505 TYR A CA  1 
ATOM 2977 C C   . TYR C 3 173 ? 179.636 183.649 133.023 1.00 48.75  ? 505 TYR A C   1 
ATOM 2978 O O   . TYR C 3 173 ? 178.919 183.811 132.034 1.00 48.75  ? 505 TYR A O   1 
ATOM 2979 C CB  . TYR C 3 173 ? 180.431 186.005 132.693 1.00 48.75  ? 505 TYR A CB  1 
ATOM 2980 N N   . GLN C 3 174 ? 179.771 182.464 133.604 1.00 44.15  ? 506 GLN A N   1 
ATOM 2981 C CA  . GLN C 3 174 ? 179.133 181.258 133.109 1.00 44.15  ? 506 GLN A CA  1 
ATOM 2982 C C   . GLN C 3 174 ? 178.094 180.748 134.101 1.00 44.15  ? 506 GLN A C   1 
ATOM 2983 O O   . GLN C 3 174 ? 178.171 181.034 135.300 1.00 44.15  ? 506 GLN A O   1 
ATOM 2984 C CB  . GLN C 3 174 ? 180.179 180.166 132.843 1.00 44.15  ? 506 GLN A CB  1 
ATOM 2985 C CG  . GLN C 3 174 ? 180.519 179.992 131.373 1.00 44.15  ? 506 GLN A CG  1 
ATOM 2986 C CD  . GLN C 3 174 ? 181.541 178.901 131.133 1.00 44.15  ? 506 GLN A CD  1 
ATOM 2987 O OE1 . GLN C 3 174 ? 181.507 177.852 131.775 1.00 44.15  ? 506 GLN A OE1 1 
ATOM 2988 N NE2 . GLN C 3 174 ? 182.457 179.142 130.205 1.00 44.15  ? 506 GLN A NE2 1 
ATOM 2989 N N   . PRO C 3 175 ? 177.097 179.995 133.633 1.00 39.08  ? 507 PRO A N   1 
ATOM 2990 C CA  . PRO C 3 175 ? 176.026 179.536 134.533 1.00 39.08  ? 507 PRO A CA  1 
ATOM 2991 C C   . PRO C 3 175 ? 176.535 178.490 135.513 1.00 39.08  ? 507 PRO A C   1 
ATOM 2992 O O   . PRO C 3 175 ? 177.038 177.438 135.113 1.00 39.08  ? 507 PRO A O   1 
ATOM 2993 C CB  . PRO C 3 175 ? 174.986 178.949 133.573 1.00 39.08  ? 507 PRO A CB  1 
ATOM 2994 C CG  . PRO C 3 175 ? 175.769 178.564 132.369 1.00 39.08  ? 507 PRO A CG  1 
ATOM 2995 C CD  . PRO C 3 175 ? 176.849 179.592 132.238 1.00 39.08  ? 507 PRO A CD  1 
ATOM 2996 N N   . TYR C 3 176 ? 176.387 178.779 136.802 1.00 34.63  ? 508 TYR A N   1 
ATOM 2997 C CA  . TYR C 3 176 ? 176.751 177.853 137.872 1.00 34.63  ? 508 TYR A CA  1 
ATOM 2998 C C   . TYR C 3 176 ? 175.472 177.481 138.615 1.00 34.63  ? 508 TYR A C   1 
ATOM 2999 O O   . TYR C 3 176 ? 174.924 178.292 139.366 1.00 34.63  ? 508 TYR A O   1 
ATOM 3000 C CB  . TYR C 3 176 ? 177.784 178.468 138.811 1.00 34.63  ? 508 TYR A CB  1 
ATOM 3001 C CG  . TYR C 3 176 ? 179.181 178.514 138.236 1.00 34.63  ? 508 TYR A CG  1 
ATOM 3002 C CD1 . TYR C 3 176 ? 180.092 179.474 138.649 1.00 34.63  ? 508 TYR A CD1 1 
ATOM 3003 C CD2 . TYR C 3 176 ? 179.583 177.607 137.269 1.00 34.63  ? 508 TYR A CD2 1 
ATOM 3004 C CE1 . TYR C 3 176 ? 181.366 179.522 138.123 1.00 34.63  ? 508 TYR A CE1 1 
ATOM 3005 C CE2 . TYR C 3 176 ? 180.855 177.648 136.736 1.00 34.63  ? 508 TYR A CE2 1 
ATOM 3006 C CZ  . TYR C 3 176 ? 181.741 178.607 137.166 1.00 34.63  ? 508 TYR A CZ  1 
ATOM 3007 O OH  . TYR C 3 176 ? 183.009 178.649 136.637 1.00 34.63  ? 508 TYR A OH  1 
ATOM 3008 N N   . ARG C 3 177 ? 175.004 176.254 138.408 1.00 30.39  ? 509 ARG A N   1 
ATOM 3009 C CA  . ARG C 3 177 ? 173.751 175.795 138.996 1.00 30.39  ? 509 ARG A CA  1 
ATOM 3010 C C   . ARG C 3 177 ? 173.923 175.631 140.500 1.00 30.39  ? 509 ARG A C   1 
ATOM 3011 O O   . ARG C 3 177 ? 174.540 174.667 140.959 1.00 30.39  ? 509 ARG A O   1 
ATOM 3012 C CB  . ARG C 3 177 ? 173.329 174.484 138.342 1.00 30.39  ? 509 ARG A CB  1 
ATOM 3013 C CG  . ARG C 3 177 ? 172.990 174.630 136.872 1.00 30.39  ? 509 ARG A CG  1 
ATOM 3014 C CD  . ARG C 3 177 ? 172.658 173.301 136.218 1.00 30.39  ? 509 ARG A CD  1 
ATOM 3015 N NE  . ARG C 3 177 ? 171.424 172.714 136.720 1.00 30.39  ? 509 ARG A NE  1 
ATOM 3016 C CZ  . ARG C 3 177 ? 171.002 171.496 136.413 1.00 30.39  ? 509 ARG A CZ  1 
ATOM 3017 N NH1 . ARG C 3 177 ? 171.693 170.710 135.604 1.00 30.39  ? 509 ARG A NH1 1 
ATOM 3018 N NH2 . ARG C 3 177 ? 169.858 171.056 136.926 1.00 30.39  ? 509 ARG A NH2 1 
ATOM 3019 N N   . VAL C 3 178 ? 173.373 176.563 141.270 1.00 23.61  ? 510 VAL A N   1 
ATOM 3020 C CA  . VAL C 3 178 ? 173.548 176.583 142.717 1.00 23.61  ? 510 VAL A CA  1 
ATOM 3021 C C   . VAL C 3 178 ? 172.436 175.778 143.375 1.00 23.61  ? 510 VAL A C   1 
ATOM 3022 O O   . VAL C 3 178 ? 171.265 175.883 142.988 1.00 23.61  ? 510 VAL A O   1 
ATOM 3023 C CB  . VAL C 3 178 ? 173.572 178.024 143.245 1.00 23.61  ? 510 VAL A CB  1 
ATOM 3024 C CG1 . VAL C 3 178 ? 173.853 178.036 144.731 1.00 23.61  ? 510 VAL A CG1 1 
ATOM 3025 C CG2 . VAL C 3 178 ? 174.620 178.825 142.511 1.00 23.61  ? 510 VAL A CG2 1 
ATOM 3026 N N   . VAL C 3 179 ? 172.804 174.958 144.358 1.00 21.70  ? 511 VAL A N   1 
ATOM 3027 C CA  . VAL C 3 179 ? 171.858 174.175 145.150 1.00 21.70  ? 511 VAL A CA  1 
ATOM 3028 C C   . VAL C 3 179 ? 172.203 174.417 146.614 1.00 21.70  ? 511 VAL A C   1 
ATOM 3029 O O   . VAL C 3 179 ? 173.046 173.720 147.184 1.00 21.70  ? 511 VAL A O   1 
ATOM 3030 C CB  . VAL C 3 179 ? 171.905 172.683 144.813 1.00 21.70  ? 511 VAL A CB  1 
ATOM 3031 C CG1 . VAL C 3 179 ? 170.989 171.902 145.735 1.00 21.70  ? 511 VAL A CG1 1 
ATOM 3032 C CG2 . VAL C 3 179 ? 171.509 172.461 143.373 1.00 21.70  ? 511 VAL A CG2 1 
ATOM 3033 N N   . VAL C 3 180 ? 171.554 175.400 147.225 1.00 25.93  ? 512 VAL A N   1 
ATOM 3034 C CA  . VAL C 3 180 ? 171.808 175.763 148.613 1.00 25.93  ? 512 VAL A CA  1 
ATOM 3035 C C   . VAL C 3 180 ? 171.048 174.789 149.505 1.00 25.93  ? 512 VAL A C   1 
ATOM 3036 O O   . VAL C 3 180 ? 169.816 174.794 149.534 1.00 25.93  ? 512 VAL A O   1 
ATOM 3037 C CB  . VAL C 3 180 ? 171.388 177.208 148.895 1.00 25.93  ? 512 VAL A CB  1 
ATOM 3038 C CG1 . VAL C 3 180 ? 171.793 177.611 150.296 1.00 25.93  ? 512 VAL A CG1 1 
ATOM 3039 C CG2 . VAL C 3 180 ? 171.996 178.142 147.871 1.00 25.93  ? 512 VAL A CG2 1 
ATOM 3040 N N   . LEU C 3 181 ? 171.780 173.949 150.229 1.00 32.35  ? 513 LEU A N   1 
ATOM 3041 C CA  . LEU C 3 181 ? 171.169 173.080 151.225 1.00 32.35  ? 513 LEU A CA  1 
ATOM 3042 C C   . LEU C 3 181 ? 170.997 173.849 152.527 1.00 32.35  ? 513 LEU A C   1 
ATOM 3043 O O   . LEU C 3 181 ? 171.923 174.524 152.985 1.00 32.35  ? 513 LEU A O   1 
ATOM 3044 C CB  . LEU C 3 181 ? 172.022 171.833 151.456 1.00 32.35  ? 513 LEU A CB  1 
ATOM 3045 C CG  . LEU C 3 181 ? 171.863 170.638 150.513 1.00 32.35  ? 513 LEU A CG  1 
ATOM 3046 C CD1 . LEU C 3 181 ? 170.466 170.077 150.613 1.00 32.35  ? 513 LEU A CD1 1 
ATOM 3047 C CD2 . LEU C 3 181 ? 172.174 171.005 149.080 1.00 32.35  ? 513 LEU A CD2 1 
ATOM 3048 N N   . SER C 3 182 ? 169.811 173.755 153.117 1.00 37.27  ? 514 SER A N   1 
ATOM 3049 C CA  . SER C 3 182 ? 169.490 174.441 154.358 1.00 37.27  ? 514 SER A CA  1 
ATOM 3050 C C   . SER C 3 182 ? 168.992 173.427 155.375 1.00 37.27  ? 514 SER A C   1 
ATOM 3051 O O   . SER C 3 182 ? 168.058 172.667 155.093 1.00 37.27  ? 514 SER A O   1 
ATOM 3052 C CB  . SER C 3 182 ? 168.437 175.526 154.131 1.00 37.27  ? 514 SER A CB  1 
ATOM 3053 O OG  . SER C 3 182 ? 167.999 176.071 155.361 1.00 37.27  ? 514 SER A OG  1 
ATOM 3054 N N   . PHE C 3 183 ? 169.621 173.421 156.549 1.00 40.91  ? 515 PHE A N   1 
ATOM 3055 C CA  . PHE C 3 183 ? 169.255 172.551 157.653 1.00 40.91  ? 515 PHE A CA  1 
ATOM 3056 C C   . PHE C 3 183 ? 168.897 173.396 158.866 1.00 40.91  ? 515 PHE A C   1 
ATOM 3057 O O   . PHE C 3 183 ? 169.307 174.555 158.978 1.00 40.91  ? 515 PHE A O   1 
ATOM 3058 C CB  . PHE C 3 183 ? 170.397 171.598 158.033 1.00 40.91  ? 515 PHE A CB  1 
ATOM 3059 C CG  . PHE C 3 183 ? 171.223 171.128 156.870 1.00 40.91  ? 515 PHE A CG  1 
ATOM 3060 C CD1 . PHE C 3 183 ? 170.638 170.478 155.799 1.00 40.91  ? 515 PHE A CD1 1 
ATOM 3061 C CD2 . PHE C 3 183 ? 172.593 171.326 156.858 1.00 40.91  ? 515 PHE A CD2 1 
ATOM 3062 C CE1 . PHE C 3 183 ? 171.403 170.042 154.735 1.00 40.91  ? 515 PHE A CE1 1 
ATOM 3063 C CE2 . PHE C 3 183 ? 173.361 170.892 155.797 1.00 40.91  ? 515 PHE A CE2 1 
ATOM 3064 C CZ  . PHE C 3 183 ? 172.766 170.249 154.736 1.00 40.91  ? 515 PHE A CZ  1 
ATOM 3065 N N   . GLU C 3 184 ? 168.127 172.807 159.777 1.00 56.67  ? 516 GLU A N   1 
ATOM 3066 C CA  . GLU C 3 184 ? 167.812 173.441 161.049 1.00 56.67  ? 516 GLU A CA  1 
ATOM 3067 C C   . GLU C 3 184 ? 168.035 172.445 162.175 1.00 56.67  ? 516 GLU A C   1 
ATOM 3068 O O   . GLU C 3 184 ? 167.721 171.259 162.038 1.00 56.67  ? 516 GLU A O   1 
ATOM 3069 C CB  . GLU C 3 184 ? 166.371 173.965 161.083 1.00 56.67  ? 516 GLU A CB  1 
ATOM 3070 C CG  . GLU C 3 184 ? 166.111 175.121 160.130 1.00 56.67  ? 516 GLU A CG  1 
ATOM 3071 C CD  . GLU C 3 184 ? 164.675 175.603 160.174 1.00 56.67  ? 516 GLU A CD  1 
ATOM 3072 O OE1 . GLU C 3 184 ? 163.849 174.957 160.852 1.00 56.67  ? 516 GLU A OE1 1 
ATOM 3073 O OE2 . GLU C 3 184 ? 164.372 176.631 159.532 1.00 56.67  ? 516 GLU A OE2 1 
ATOM 3074 N N   . LEU C 3 185 ? 168.573 172.935 163.287 1.00 66.18  ? 517 LEU A N   1 
ATOM 3075 C CA  . LEU C 3 185 ? 168.880 172.088 164.433 1.00 66.18  ? 517 LEU A CA  1 
ATOM 3076 C C   . LEU C 3 185 ? 167.610 171.578 165.107 1.00 66.18  ? 517 LEU A C   1 
ATOM 3077 O O   . LEU C 3 185 ? 167.669 170.924 166.148 1.00 66.18  ? 517 LEU A O   1 
ATOM 3078 C CB  . LEU C 3 185 ? 169.752 172.853 165.436 1.00 66.18  ? 517 LEU A CB  1 
ATOM 3079 C CG  . LEU C 3 185 ? 169.231 174.179 166.006 1.00 66.18  ? 517 LEU A CG  1 
ATOM 3080 C CD1 . LEU C 3 185 ? 168.395 173.978 167.268 1.00 66.18  ? 517 LEU A CD1 1 
ATOM 3081 C CD2 . LEU C 3 185 ? 170.385 175.137 166.272 1.00 66.18  ? 517 LEU A CD2 1 
ATOM 3082 N N   . ALA C 3 188 ? 163.419 169.101 169.257 1.00 61.12  ? 520 ALA A N   1 
ATOM 3083 C CA  . ALA C 3 188 ? 162.714 169.132 167.983 1.00 61.12  ? 520 ALA A CA  1 
ATOM 3084 C C   . ALA C 3 188 ? 162.854 167.802 167.253 1.00 61.12  ? 520 ALA A C   1 
ATOM 3085 O O   . ALA C 3 188 ? 163.968 167.327 167.036 1.00 61.12  ? 520 ALA A O   1 
ATOM 3086 C CB  . ALA C 3 188 ? 163.232 170.269 167.118 1.00 61.12  ? 520 ALA A CB  1 
ATOM 3087 N N   . PRO C 3 189 ? 161.724 167.195 166.890 1.00 57.45  ? 521 PRO A N   1 
ATOM 3088 C CA  . PRO C 3 189 ? 161.776 165.935 166.137 1.00 57.45  ? 521 PRO A CA  1 
ATOM 3089 C C   . PRO C 3 189 ? 162.523 166.115 164.824 1.00 57.45  ? 521 PRO A C   1 
ATOM 3090 O O   . PRO C 3 189 ? 162.397 167.140 164.151 1.00 57.45  ? 521 PRO A O   1 
ATOM 3091 C CB  . PRO C 3 189 ? 160.302 165.588 165.899 1.00 57.45  ? 521 PRO A CB  1 
ATOM 3092 C CG  . PRO C 3 189 ? 159.506 166.471 166.783 1.00 57.45  ? 521 PRO A CG  1 
ATOM 3093 C CD  . PRO C 3 189 ? 160.364 167.564 167.318 1.00 57.45  ? 521 PRO A CD  1 
ATOM 3094 N N   . ALA C 3 190 ? 163.306 165.102 164.462 1.00 57.05  ? 522 ALA A N   1 
ATOM 3095 C CA  . ALA C 3 190 ? 164.148 165.147 163.276 1.00 57.05  ? 522 ALA A CA  1 
ATOM 3096 C C   . ALA C 3 190 ? 163.986 163.859 162.485 1.00 57.05  ? 522 ALA A C   1 
ATOM 3097 O O   . ALA C 3 190 ? 163.952 162.769 163.063 1.00 57.05  ? 522 ALA A O   1 
ATOM 3098 C CB  . ALA C 3 190 ? 165.612 165.358 163.658 1.00 57.05  ? 522 ALA A CB  1 
ATOM 3099 N N   . THR C 3 191 ? 163.890 163.986 161.155 1.00 58.51  ? 523 THR A N   1 
ATOM 3100 C CA  . THR C 3 191 ? 163.542 162.831 160.334 1.00 58.51  ? 523 THR A CA  1 
ATOM 3101 C C   . THR C 3 191 ? 164.314 162.745 159.018 1.00 58.51  ? 523 THR A C   1 
ATOM 3102 O O   . THR C 3 191 ? 163.886 162.018 158.113 1.00 58.51  ? 523 THR A O   1 
ATOM 3103 C CB  . THR C 3 191 ? 162.039 162.833 160.033 1.00 58.51  ? 523 THR A CB  1 
ATOM 3104 O OG1 . THR C 3 191 ? 161.678 161.614 159.373 1.00 58.51  ? 523 THR A OG1 1 
ATOM 3105 C CG2 . THR C 3 191 ? 161.670 164.021 159.153 1.00 58.51  ? 523 THR A CG2 1 
ATOM 3106 N N   . VAL C 3 192 ? 165.438 163.444 158.876 1.00 54.45  ? 524 VAL A N   1 
ATOM 3107 C CA  . VAL C 3 192 ? 166.174 163.403 157.617 1.00 54.45  ? 524 VAL A CA  1 
ATOM 3108 C C   . VAL C 3 192 ? 167.609 162.964 157.899 1.00 54.45  ? 524 VAL A C   1 
ATOM 3109 O O   . VAL C 3 192 ? 168.554 163.372 157.215 1.00 54.45  ? 524 VAL A O   1 
ATOM 3110 C CB  . VAL C 3 192 ? 166.101 164.762 156.888 1.00 54.45  ? 524 VAL A CB  1 
ATOM 3111 C CG1 . VAL C 3 192 ? 166.808 165.857 157.674 1.00 54.45  ? 524 VAL A CG1 1 
ATOM 3112 C CG2 . VAL C 3 192 ? 166.589 164.666 155.436 1.00 54.45  ? 524 VAL A CG2 1 
ATOM 3113 N N   . CYS C 3 193 ? 167.783 162.113 158.907 1.00 61.42  ? 525 CYS A N   1 
ATOM 3114 C CA  . CYS C 3 193 ? 169.102 161.650 159.309 1.00 61.42  ? 525 CYS A CA  1 
ATOM 3115 C C   . CYS C 3 193 ? 169.126 160.133 159.409 1.00 61.42  ? 525 CYS A C   1 
ATOM 3116 O O   . CYS C 3 193 ? 168.088 159.466 159.432 1.00 61.42  ? 525 CYS A O   1 
ATOM 3117 C CB  . CYS C 3 193 ? 169.522 162.260 160.647 1.00 61.42  ? 525 CYS A CB  1 
ATOM 3118 S SG  . CYS C 3 193 ? 168.595 161.648 162.071 1.00 61.42  ? 525 CYS A SG  1 
ATOM 3119 N N   . GLY C 3 194 ? 170.341 159.595 159.479 1.00 63.46  ? 526 GLY A N   1 
ATOM 3120 C CA  . GLY C 3 194 ? 170.549 158.178 159.653 1.00 63.46  ? 526 GLY A CA  1 
ATOM 3121 C C   . GLY C 3 194 ? 170.682 157.807 161.116 1.00 63.46  ? 526 GLY A C   1 
ATOM 3122 O O   . GLY C 3 194 ? 169.726 157.899 161.893 1.00 63.46  ? 526 GLY A O   1 
ATOM 3123 N N   . PRO C 3 195 ? 171.881 157.361 161.520 1.00 62.73  ? 527 PRO A N   1 
ATOM 3124 C CA  . PRO C 3 195 ? 172.176 157.031 162.919 1.00 62.73  ? 527 PRO A CA  1 
ATOM 3125 C C   . PRO C 3 195 ? 171.905 158.193 163.874 1.00 62.73  ? 527 PRO A C   1 
ATOM 3126 O O   . PRO C 3 195 ? 172.629 159.186 163.897 1.00 62.73  ? 527 PRO A O   1 
ATOM 3127 C CB  . PRO C 3 195 ? 173.670 156.691 162.888 1.00 62.73  ? 527 PRO A CB  1 
ATOM 3128 C CG  . PRO C 3 195 ? 173.919 156.227 161.496 1.00 62.73  ? 527 PRO A CG  1 
ATOM 3129 C CD  . PRO C 3 195 ? 173.016 157.058 160.630 1.00 62.73  ? 527 PRO A CD  1 
ATOM 3130 O OXT . PRO C 3 195 ? 170.951 158.162 164.650 1.00 62.73  ? 527 PRO A OXT 1 
ATOM 3131 N N   . THR D 3 1   ? 179.356 236.045 157.492 1.00 119.77 ? 333 THR D N   1 
ATOM 3132 C CA  . THR D 3 1   ? 180.323 236.464 158.499 1.00 119.77 ? 333 THR D CA  1 
ATOM 3133 C C   . THR D 3 1   ? 181.604 236.965 157.837 1.00 119.77 ? 333 THR D C   1 
ATOM 3134 O O   . THR D 3 1   ? 182.207 237.941 158.284 1.00 119.77 ? 333 THR D O   1 
ATOM 3135 C CB  . THR D 3 1   ? 180.662 235.314 159.470 1.00 119.77 ? 333 THR D CB  1 
ATOM 3136 O OG1 . THR D 3 1   ? 179.452 234.771 160.013 1.00 119.77 ? 333 THR D OG1 1 
ATOM 3137 C CG2 . THR D 3 1   ? 181.537 235.813 160.607 1.00 119.77 ? 333 THR D CG2 1 
ATOM 3138 N N   . ASN D 3 2   ? 182.008 236.293 156.761 1.00 121.11 ? 334 ASN D N   1 
ATOM 3139 C CA  . ASN D 3 2   ? 183.224 236.628 156.037 1.00 121.11 ? 334 ASN D CA  1 
ATOM 3140 C C   . ASN D 3 2   ? 182.901 236.857 154.569 1.00 121.11 ? 334 ASN D C   1 
ATOM 3141 O O   . ASN D 3 2   ? 181.964 236.270 154.022 1.00 121.11 ? 334 ASN D O   1 
ATOM 3142 C CB  . ASN D 3 2   ? 184.281 235.521 156.171 1.00 121.11 ? 334 ASN D CB  1 
ATOM 3143 C CG  . ASN D 3 2   ? 185.619 235.915 155.574 1.00 121.11 ? 334 ASN D CG  1 
ATOM 3144 O OD1 . ASN D 3 2   ? 185.883 237.092 155.331 1.00 121.11 ? 334 ASN D OD1 1 
ATOM 3145 N ND2 . ASN D 3 2   ? 186.471 234.927 155.332 1.00 121.11 ? 334 ASN D ND2 1 
ATOM 3146 N N   . LEU D 3 3   ? 183.691 237.723 153.937 1.00 118.52 ? 335 LEU D N   1 
ATOM 3147 C CA  . LEU D 3 3   ? 183.565 238.017 152.516 1.00 118.52 ? 335 LEU D CA  1 
ATOM 3148 C C   . LEU D 3 3   ? 184.874 237.666 151.828 1.00 118.52 ? 335 LEU D C   1 
ATOM 3149 O O   . LEU D 3 3   ? 185.949 238.041 152.308 1.00 118.52 ? 335 LEU D O   1 
ATOM 3150 C CB  . LEU D 3 3   ? 183.222 239.492 152.277 1.00 118.52 ? 335 LEU D CB  1 
ATOM 3151 C CG  . LEU D 3 3   ? 181.952 240.035 152.932 1.00 118.52 ? 335 LEU D CG  1 
ATOM 3152 C CD1 . LEU D 3 3   ? 182.275 240.701 154.261 1.00 118.52 ? 335 LEU D CD1 1 
ATOM 3153 C CD2 . LEU D 3 3   ? 181.248 241.007 152.000 1.00 118.52 ? 335 LEU D CD2 1 
ATOM 3154 N N   . CYS D 3 4   ? 184.784 236.945 150.714 1.00 117.38 ? 336 CYS D N   1 
ATOM 3155 C CA  . CYS D 3 4   ? 185.977 236.595 149.964 1.00 117.38 ? 336 CYS D CA  1 
ATOM 3156 C C   . CYS D 3 4   ? 186.567 237.838 149.299 1.00 117.38 ? 336 CYS D C   1 
ATOM 3157 O O   . CYS D 3 4   ? 185.853 238.810 149.037 1.00 117.38 ? 336 CYS D O   1 
ATOM 3158 C CB  . CYS D 3 4   ? 185.659 235.531 148.918 1.00 117.38 ? 336 CYS D CB  1 
ATOM 3159 S SG  . CYS D 3 4   ? 185.572 233.869 149.613 1.00 117.38 ? 336 CYS D SG  1 
ATOM 3160 N N   . PRO D 3 5   ? 187.875 237.835 149.017 1.00 108.67 ? 337 PRO D N   1 
ATOM 3161 C CA  . PRO D 3 5   ? 188.519 239.053 148.510 1.00 108.67 ? 337 PRO D CA  1 
ATOM 3162 C C   . PRO D 3 5   ? 188.113 239.417 147.090 1.00 108.67 ? 337 PRO D C   1 
ATOM 3163 O O   . PRO D 3 5   ? 188.964 239.495 146.199 1.00 108.67 ? 337 PRO D O   1 
ATOM 3164 C CB  . PRO D 3 5   ? 190.013 238.714 148.588 1.00 108.67 ? 337 PRO D CB  1 
ATOM 3165 C CG  . PRO D 3 5   ? 190.058 237.230 148.500 1.00 108.67 ? 337 PRO D CG  1 
ATOM 3166 C CD  . PRO D 3 5   ? 188.852 236.758 149.253 1.00 108.67 ? 337 PRO D CD  1 
ATOM 3167 N N   . PHE D 3 6   ? 186.816 239.641 146.867 1.00 105.55 ? 338 PHE D N   1 
ATOM 3168 C CA  . PHE D 3 6   ? 186.378 240.213 145.601 1.00 105.55 ? 338 PHE D CA  1 
ATOM 3169 C C   . PHE D 3 6   ? 186.849 241.651 145.440 1.00 105.55 ? 338 PHE D C   1 
ATOM 3170 O O   . PHE D 3 6   ? 186.978 242.126 144.308 1.00 105.55 ? 338 PHE D O   1 
ATOM 3171 C CB  . PHE D 3 6   ? 184.856 240.144 145.485 1.00 105.55 ? 338 PHE D CB  1 
ATOM 3172 C CG  . PHE D 3 6   ? 184.314 238.745 145.453 1.00 105.55 ? 338 PHE D CG  1 
ATOM 3173 C CD1 . PHE D 3 6   ? 184.712 237.857 144.467 1.00 105.55 ? 338 PHE D CD1 1 
ATOM 3174 C CD2 . PHE D 3 6   ? 183.406 238.316 146.406 1.00 105.55 ? 338 PHE D CD2 1 
ATOM 3175 C CE1 . PHE D 3 6   ? 184.216 236.569 144.433 1.00 105.55 ? 338 PHE D CE1 1 
ATOM 3176 C CE2 . PHE D 3 6   ? 182.906 237.029 146.378 1.00 105.55 ? 338 PHE D CE2 1 
ATOM 3177 C CZ  . PHE D 3 6   ? 183.311 236.154 145.390 1.00 105.55 ? 338 PHE D CZ  1 
ATOM 3178 N N   . GLY D 3 7   ? 187.102 242.350 146.544 1.00 102.30 ? 339 GLY D N   1 
ATOM 3179 C CA  . GLY D 3 7   ? 187.693 243.669 146.513 1.00 102.30 ? 339 GLY D CA  1 
ATOM 3180 C C   . GLY D 3 7   ? 189.199 243.688 146.428 1.00 102.30 ? 339 GLY D C   1 
ATOM 3181 O O   . GLY D 3 7   ? 189.798 244.766 146.403 1.00 102.30 ? 339 GLY D O   1 
ATOM 3182 N N   . GLU D 3 8   ? 189.831 242.517 146.387 1.00 100.62 ? 340 GLU D N   1 
ATOM 3183 C CA  . GLU D 3 8   ? 191.278 242.390 146.247 1.00 100.62 ? 340 GLU D CA  1 
ATOM 3184 C C   . GLU D 3 8   ? 191.692 241.702 144.958 1.00 100.62 ? 340 GLU D C   1 
ATOM 3185 O O   . GLU D 3 8   ? 192.703 242.079 144.364 1.00 100.62 ? 340 GLU D O   1 
ATOM 3186 C CB  . GLU D 3 8   ? 191.863 241.624 147.444 1.00 100.62 ? 340 GLU D CB  1 
ATOM 3187 C CG  . GLU D 3 8   ? 192.046 242.466 148.698 1.00 100.62 ? 340 GLU D CG  1 
ATOM 3188 C CD  . GLU D 3 8   ? 192.668 243.819 148.410 1.00 100.62 ? 340 GLU D CD  1 
ATOM 3189 O OE1 . GLU D 3 8   ? 193.878 243.865 148.106 1.00 100.62 ? 340 GLU D OE1 1 
ATOM 3190 O OE2 . GLU D 3 8   ? 191.948 244.836 148.492 1.00 100.62 ? 340 GLU D OE2 1 
ATOM 3191 N N   . VAL D 3 9   ? 190.940 240.694 144.512 1.00 96.85  ? 341 VAL D N   1 
ATOM 3192 C CA  . VAL D 3 9   ? 191.230 240.065 143.228 1.00 96.85  ? 341 VAL D CA  1 
ATOM 3193 C C   . VAL D 3 9   ? 191.003 241.054 142.092 1.00 96.85  ? 341 VAL D C   1 
ATOM 3194 O O   . VAL D 3 9   ? 191.751 241.073 141.106 1.00 96.85  ? 341 VAL D O   1 
ATOM 3195 C CB  . VAL D 3 9   ? 190.384 238.791 143.055 1.00 96.85  ? 341 VAL D CB  1 
ATOM 3196 C CG1 . VAL D 3 9   ? 190.488 238.262 141.632 1.00 96.85  ? 341 VAL D CG1 1 
ATOM 3197 C CG2 . VAL D 3 9   ? 190.821 237.730 144.052 1.00 96.85  ? 341 VAL D CG2 1 
ATOM 3198 N N   . PHE D 3 10  ? 189.980 241.894 142.212 1.00 97.98  ? 342 PHE D N   1 
ATOM 3199 C CA  . PHE D 3 10  ? 189.704 242.930 141.227 1.00 97.98  ? 342 PHE D CA  1 
ATOM 3200 C C   . PHE D 3 10  ? 190.398 244.248 141.546 1.00 97.98  ? 342 PHE D C   1 
ATOM 3201 O O   . PHE D 3 10  ? 190.227 245.218 140.800 1.00 97.98  ? 342 PHE D O   1 
ATOM 3202 C CB  . PHE D 3 10  ? 188.192 243.153 141.109 1.00 97.98  ? 342 PHE D CB  1 
ATOM 3203 C CG  . PHE D 3 10  ? 187.445 241.966 140.568 1.00 97.98  ? 342 PHE D CG  1 
ATOM 3204 C CD1 . PHE D 3 10  ? 186.985 240.972 141.415 1.00 97.98  ? 342 PHE D CD1 1 
ATOM 3205 C CD2 . PHE D 3 10  ? 187.200 241.847 139.213 1.00 97.98  ? 342 PHE D CD2 1 
ATOM 3206 C CE1 . PHE D 3 10  ? 186.298 239.882 140.919 1.00 97.98  ? 342 PHE D CE1 1 
ATOM 3207 C CE2 . PHE D 3 10  ? 186.513 240.759 138.711 1.00 97.98  ? 342 PHE D CE2 1 
ATOM 3208 C CZ  . PHE D 3 10  ? 186.063 239.775 139.566 1.00 97.98  ? 342 PHE D CZ  1 
ATOM 3209 N N   . ASN D 3 11  ? 191.172 244.307 142.628 1.00 98.63  ? 343 ASN D N   1 
ATOM 3210 C CA  . ASN D 3 11  ? 191.900 245.520 142.991 1.00 98.63  ? 343 ASN D CA  1 
ATOM 3211 C C   . ASN D 3 11  ? 193.114 245.111 143.814 1.00 98.63  ? 343 ASN D C   1 
ATOM 3212 O O   . ASN D 3 11  ? 192.980 244.804 145.002 1.00 98.63  ? 343 ASN D O   1 
ATOM 3213 C CB  . ASN D 3 11  ? 191.008 246.485 143.768 1.00 98.63  ? 343 ASN D CB  1 
ATOM 3214 C CG  . ASN D 3 11  ? 191.624 247.862 143.914 1.00 98.63  ? 343 ASN D CG  1 
ATOM 3215 O OD1 . ASN D 3 11  ? 192.688 248.141 143.363 1.00 98.63  ? 343 ASN D OD1 1 
ATOM 3216 N ND2 . ASN D 3 11  ? 190.958 248.731 144.662 1.00 98.63  ? 343 ASN D ND2 1 
ATOM 3217 N N   . ALA D 3 12  ? 194.289 245.114 143.193 1.00 105.67 ? 344 ALA D N   1 
ATOM 3218 C CA  . ALA D 3 12  ? 195.521 244.728 143.873 1.00 105.67 ? 344 ALA D CA  1 
ATOM 3219 C C   . ALA D 3 12  ? 196.691 245.425 143.181 1.00 105.67 ? 344 ALA D C   1 
ATOM 3220 O O   . ALA D 3 12  ? 196.494 246.363 142.403 1.00 105.67 ? 344 ALA D O   1 
ATOM 3221 C CB  . ALA D 3 12  ? 195.668 243.198 143.896 1.00 105.67 ? 344 ALA D CB  1 
ATOM 3222 N N   . THR D 3 13  ? 197.912 244.967 143.473 1.00 108.05 ? 345 THR D N   1 
ATOM 3223 C CA  . THR D 3 13  ? 199.103 245.576 142.887 1.00 108.05 ? 345 THR D CA  1 
ATOM 3224 C C   . THR D 3 13  ? 199.137 245.379 141.376 1.00 108.05 ? 345 THR D C   1 
ATOM 3225 O O   . THR D 3 13  ? 199.356 246.331 140.618 1.00 108.05 ? 345 THR D O   1 
ATOM 3226 C CB  . THR D 3 13  ? 200.363 244.995 143.535 1.00 108.05 ? 345 THR D CB  1 
ATOM 3227 O OG1 . THR D 3 13  ? 200.360 243.569 143.395 1.00 108.05 ? 345 THR D OG1 1 
ATOM 3228 C CG2 . THR D 3 13  ? 200.424 245.354 145.013 1.00 108.05 ? 345 THR D CG2 1 
ATOM 3229 N N   . ARG D 3 14  ? 198.916 244.148 140.921 1.00 112.96 ? 346 ARG D N   1 
ATOM 3230 C CA  . ARG D 3 14  ? 198.956 243.828 139.502 1.00 112.96 ? 346 ARG D CA  1 
ATOM 3231 C C   . ARG D 3 14  ? 198.371 242.440 139.290 1.00 112.96 ? 346 ARG D C   1 
ATOM 3232 O O   . ARG D 3 14  ? 197.936 241.773 140.232 1.00 112.96 ? 346 ARG D O   1 
ATOM 3233 C CB  . ARG D 3 14  ? 200.384 243.900 138.947 1.00 112.96 ? 346 ARG D CB  1 
ATOM 3234 N N   . PHE D 3 15  ? 198.363 242.012 138.031 1.00 116.20 ? 347 PHE D N   1 
ATOM 3235 C CA  . PHE D 3 15  ? 197.903 240.685 137.651 1.00 116.20 ? 347 PHE D CA  1 
ATOM 3236 C C   . PHE D 3 15  ? 199.089 239.790 137.310 1.00 116.20 ? 347 PHE D C   1 
ATOM 3237 O O   . PHE D 3 15  ? 200.029 240.205 136.628 1.00 116.20 ? 347 PHE D O   1 
ATOM 3238 C CB  . PHE D 3 15  ? 196.940 240.755 136.464 1.00 116.20 ? 347 PHE D CB  1 
ATOM 3239 C CG  . PHE D 3 15  ? 195.514 241.019 136.857 1.00 116.20 ? 347 PHE D CG  1 
ATOM 3240 C CD1 . PHE D 3 15  ? 195.191 241.340 138.165 1.00 116.20 ? 347 PHE D CD1 1 
ATOM 3241 C CD2 . PHE D 3 15  ? 194.497 240.934 135.923 1.00 116.20 ? 347 PHE D CD2 1 
ATOM 3242 C CE1 . PHE D 3 15  ? 193.882 241.579 138.532 1.00 116.20 ? 347 PHE D CE1 1 
ATOM 3243 C CE2 . PHE D 3 15  ? 193.186 241.170 136.285 1.00 116.20 ? 347 PHE D CE2 1 
ATOM 3244 C CZ  . PHE D 3 15  ? 192.879 241.493 137.592 1.00 116.20 ? 347 PHE D CZ  1 
ATOM 3245 N N   . ALA D 3 16  ? 199.030 238.551 137.792 1.00 126.13 ? 348 ALA D N   1 
ATOM 3246 C CA  . ALA D 3 16  ? 200.142 237.624 137.648 1.00 126.13 ? 348 ALA D CA  1 
ATOM 3247 C C   . ALA D 3 16  ? 200.198 237.070 136.225 1.00 126.13 ? 348 ALA D C   1 
ATOM 3248 O O   . ALA D 3 16  ? 199.408 237.433 135.348 1.00 126.13 ? 348 ALA D O   1 
ATOM 3249 C CB  . ALA D 3 16  ? 200.025 236.495 138.669 1.00 126.13 ? 348 ALA D CB  1 
ATOM 3250 N N   . SER D 3 17  ? 201.154 236.172 136.001 1.00 129.76 ? 349 SER D N   1 
ATOM 3251 C CA  . SER D 3 17  ? 201.354 235.589 134.682 1.00 129.76 ? 349 SER D CA  1 
ATOM 3252 C C   . SER D 3 17  ? 200.191 234.680 134.304 1.00 129.76 ? 349 SER D C   1 
ATOM 3253 O O   . SER D 3 17  ? 199.490 234.136 135.162 1.00 129.76 ? 349 SER D O   1 
ATOM 3254 C CB  . SER D 3 17  ? 202.665 234.805 134.640 1.00 129.76 ? 349 SER D CB  1 
ATOM 3255 O OG  . SER D 3 17  ? 203.752 235.606 135.071 1.00 129.76 ? 349 SER D OG  1 
ATOM 3256 N N   . VAL D 3 18  ? 199.991 234.523 132.994 1.00 132.92 ? 350 VAL D N   1 
ATOM 3257 C CA  . VAL D 3 18  ? 198.898 233.693 132.496 1.00 132.92 ? 350 VAL D CA  1 
ATOM 3258 C C   . VAL D 3 18  ? 199.095 232.239 132.907 1.00 132.92 ? 350 VAL D C   1 
ATOM 3259 O O   . VAL D 3 18  ? 198.138 231.553 133.287 1.00 132.92 ? 350 VAL D O   1 
ATOM 3260 C CB  . VAL D 3 18  ? 198.775 233.839 130.969 1.00 132.92 ? 350 VAL D CB  1 
ATOM 3261 C CG1 . VAL D 3 18  ? 197.654 232.960 130.438 1.00 132.92 ? 350 VAL D CG1 1 
ATOM 3262 C CG2 . VAL D 3 18  ? 198.543 235.294 130.594 1.00 132.92 ? 350 VAL D CG2 1 
ATOM 3263 N N   . TYR D 3 19  ? 200.334 231.745 132.840 1.00 134.59 ? 351 TYR D N   1 
ATOM 3264 C CA  . TYR D 3 19  ? 200.600 230.344 133.148 1.00 134.59 ? 351 TYR D CA  1 
ATOM 3265 C C   . TYR D 3 19  ? 200.260 229.986 134.589 1.00 134.59 ? 351 TYR D C   1 
ATOM 3266 O O   . TYR D 3 19  ? 199.700 228.911 134.832 1.00 134.59 ? 351 TYR D O   1 
ATOM 3267 C CB  . TYR D 3 19  ? 202.068 230.016 132.866 1.00 134.59 ? 351 TYR D CB  1 
ATOM 3268 N N   . ALA D 3 20  ? 200.578 230.854 135.546 1.00 135.99 ? 352 ALA D N   1 
ATOM 3269 C CA  . ALA D 3 20  ? 200.322 230.600 136.961 1.00 135.99 ? 352 ALA D CA  1 
ATOM 3270 C C   . ALA D 3 20  ? 199.372 231.679 137.473 1.00 135.99 ? 352 ALA D C   1 
ATOM 3271 O O   . ALA D 3 20  ? 199.786 232.774 137.859 1.00 135.99 ? 352 ALA D O   1 
ATOM 3272 C CB  . ALA D 3 20  ? 201.631 230.569 137.754 1.00 135.99 ? 352 ALA D CB  1 
ATOM 3273 N N   . TRP D 3 21  ? 198.080 231.358 137.474 1.00 132.93 ? 353 TRP D N   1 
ATOM 3274 C CA  . TRP D 3 21  ? 197.073 232.293 137.959 1.00 132.93 ? 353 TRP D CA  1 
ATOM 3275 C C   . TRP D 3 21  ? 197.176 232.438 139.471 1.00 132.93 ? 353 TRP D C   1 
ATOM 3276 O O   . TRP D 3 21  ? 197.555 231.493 140.170 1.00 132.93 ? 353 TRP D O   1 
ATOM 3277 C CB  . TRP D 3 21  ? 195.677 231.815 137.564 1.00 132.93 ? 353 TRP D CB  1 
ATOM 3278 C CG  . TRP D 3 21  ? 195.493 231.646 136.090 1.00 132.93 ? 353 TRP D CG  1 
ATOM 3279 C CD1 . TRP D 3 21  ? 195.199 232.622 135.183 1.00 132.93 ? 353 TRP D CD1 1 
ATOM 3280 C CD2 . TRP D 3 21  ? 195.572 230.422 135.350 1.00 132.93 ? 353 TRP D CD2 1 
ATOM 3281 N NE1 . TRP D 3 21  ? 195.101 232.083 133.924 1.00 132.93 ? 353 TRP D NE1 1 
ATOM 3282 C CE2 . TRP D 3 21  ? 195.323 230.733 133.999 1.00 132.93 ? 353 TRP D CE2 1 
ATOM 3283 C CE3 . TRP D 3 21  ? 195.832 229.093 135.699 1.00 132.93 ? 353 TRP D CE3 1 
ATOM 3284 C CZ2 . TRP D 3 21  ? 195.328 229.766 132.996 1.00 132.93 ? 353 TRP D CZ2 1 
ATOM 3285 C CZ3 . TRP D 3 21  ? 195.836 228.134 134.701 1.00 132.93 ? 353 TRP D CZ3 1 
ATOM 3286 C CH2 . TRP D 3 21  ? 195.586 228.475 133.367 1.00 132.93 ? 353 TRP D CH2 1 
ATOM 3287 N N   . ASN D 3 22  ? 196.839 233.620 139.975 1.00 130.79 ? 354 ASN D N   1 
ATOM 3288 C CA  . ASN D 3 22  ? 196.882 233.878 141.408 1.00 130.79 ? 354 ASN D CA  1 
ATOM 3289 C C   . ASN D 3 22  ? 195.692 233.193 142.081 1.00 130.79 ? 354 ASN D C   1 
ATOM 3290 O O   . ASN D 3 22  ? 194.809 232.629 141.429 1.00 130.79 ? 354 ASN D O   1 
ATOM 3291 C CB  . ASN D 3 22  ? 196.904 235.380 141.675 1.00 130.79 ? 354 ASN D CB  1 
ATOM 3292 N N   . ARG D 3 23  ? 195.661 233.241 143.408 1.00 129.83 ? 355 ARG D N   1 
ATOM 3293 C CA  . ARG D 3 23  ? 194.575 232.630 144.165 1.00 129.83 ? 355 ARG D CA  1 
ATOM 3294 C C   . ARG D 3 23  ? 193.297 233.442 143.960 1.00 129.83 ? 355 ARG D C   1 
ATOM 3295 O O   . ARG D 3 23  ? 192.325 232.953 143.385 1.00 129.83 ? 355 ARG D O   1 
ATOM 3296 C CB  . ARG D 3 23  ? 194.935 232.545 145.654 1.00 129.83 ? 355 ARG D CB  1 
ATOM 3297 C CG  . ARG D 3 23  ? 193.779 232.180 146.584 1.00 129.83 ? 355 ARG D CG  1 
ATOM 3298 C CD  . ARG D 3 23  ? 192.956 231.003 146.053 1.00 129.83 ? 355 ARG D CD  1 
ATOM 3299 N NE  . ARG D 3 23  ? 191.685 230.838 146.749 1.00 129.83 ? 355 ARG D NE  1 
ATOM 3300 C CZ  . ARG D 3 23  ? 190.695 231.722 146.744 1.00 129.83 ? 355 ARG D CZ  1 
ATOM 3301 N NH1 . ARG D 3 23  ? 190.773 232.848 146.053 1.00 129.83 ? 355 ARG D NH1 1 
ATOM 3302 N NH2 . ARG D 3 23  ? 189.592 231.464 147.441 1.00 129.83 ? 355 ARG D NH2 1 
ATOM 3303 N N   . SER D 3 27  ? 186.539 230.747 149.093 1.00 122.80 ? 359 SER D N   1 
ATOM 3304 C CA  . SER D 3 27  ? 185.673 229.695 149.610 1.00 122.80 ? 359 SER D CA  1 
ATOM 3305 C C   . SER D 3 27  ? 184.838 230.202 150.780 1.00 122.80 ? 359 SER D C   1 
ATOM 3306 O O   . SER D 3 27  ? 185.190 231.199 151.399 1.00 122.80 ? 359 SER D O   1 
ATOM 3307 C CB  . SER D 3 27  ? 186.501 228.482 150.040 1.00 122.80 ? 359 SER D CB  1 
ATOM 3308 O OG  . SER D 3 27  ? 187.031 227.803 148.915 1.00 122.80 ? 359 SER D OG  1 
ATOM 3309 N N   . ASN D 3 28  ? 183.734 229.505 151.041 1.00 122.98 ? 360 ASN D N   1 
ATOM 3310 C CA  . ASN D 3 28  ? 182.795 229.760 152.141 1.00 122.98 ? 360 ASN D CA  1 
ATOM 3311 C C   . ASN D 3 28  ? 182.577 231.257 152.401 1.00 122.98 ? 360 ASN D C   1 
ATOM 3312 O O   . ASN D 3 28  ? 182.707 231.759 153.517 1.00 122.98 ? 360 ASN D O   1 
ATOM 3313 C CB  . ASN D 3 28  ? 183.210 229.001 153.413 1.00 122.98 ? 360 ASN D CB  1 
ATOM 3314 C CG  . ASN D 3 28  ? 184.578 229.408 153.967 1.00 122.98 ? 360 ASN D CG  1 
ATOM 3315 O OD1 . ASN D 3 28  ? 185.022 230.545 153.843 1.00 122.98 ? 360 ASN D OD1 1 
ATOM 3316 N ND2 . ASN D 3 28  ? 185.253 228.449 154.591 1.00 122.98 ? 360 ASN D ND2 1 
ATOM 3317 N N   . CYS D 3 29  ? 182.196 231.960 151.334 1.00 121.16 ? 361 CYS D N   1 
ATOM 3318 C CA  . CYS D 3 29  ? 181.814 233.364 151.438 1.00 121.16 ? 361 CYS D CA  1 
ATOM 3319 C C   . CYS D 3 29  ? 180.437 233.601 150.833 1.00 121.16 ? 361 CYS D C   1 
ATOM 3320 O O   . CYS D 3 29  ? 179.717 232.650 150.514 1.00 121.16 ? 361 CYS D O   1 
ATOM 3321 C CB  . CYS D 3 29  ? 182.831 234.268 150.742 1.00 121.16 ? 361 CYS D CB  1 
ATOM 3322 S SG  . CYS D 3 29  ? 184.521 234.134 151.329 1.00 121.16 ? 361 CYS D SG  1 
ATOM 3323 N N   . VAL D 3 30  ? 180.070 234.868 150.670 1.00 120.06 ? 362 VAL D N   1 
ATOM 3324 C CA  . VAL D 3 30  ? 178.825 235.258 150.019 1.00 120.06 ? 362 VAL D CA  1 
ATOM 3325 C C   . VAL D 3 30  ? 179.163 235.918 148.689 1.00 120.06 ? 362 VAL D C   1 
ATOM 3326 O O   . VAL D 3 30  ? 180.020 236.809 148.626 1.00 120.06 ? 362 VAL D O   1 
ATOM 3327 C CB  . VAL D 3 30  ? 177.994 236.193 150.915 1.00 120.06 ? 362 VAL D CB  1 
ATOM 3328 C CG1 . VAL D 3 30  ? 177.406 235.415 152.081 1.00 120.06 ? 362 VAL D CG1 1 
ATOM 3329 C CG2 . VAL D 3 30  ? 178.846 237.342 151.434 1.00 120.06 ? 362 VAL D CG2 1 
ATOM 3330 N N   . ALA D 3 31  ? 178.505 235.471 147.625 1.00 116.28 ? 363 ALA D N   1 
ATOM 3331 C CA  . ALA D 3 31  ? 178.759 235.961 146.280 1.00 116.28 ? 363 ALA D CA  1 
ATOM 3332 C C   . ALA D 3 31  ? 177.559 236.746 145.768 1.00 116.28 ? 363 ALA D C   1 
ATOM 3333 O O   . ALA D 3 31  ? 176.406 236.411 146.053 1.00 116.28 ? 363 ALA D O   1 
ATOM 3334 C CB  . ALA D 3 31  ? 179.073 234.808 145.322 1.00 116.28 ? 363 ALA D CB  1 
ATOM 3335 N N   . ASP D 3 32  ? 177.843 237.797 145.005 1.00 105.67 ? 364 ASP D N   1 
ATOM 3336 C CA  . ASP D 3 32  ? 176.807 238.652 144.444 1.00 105.67 ? 364 ASP D CA  1 
ATOM 3337 C C   . ASP D 3 32  ? 177.232 239.059 143.038 1.00 105.67 ? 364 ASP D C   1 
ATOM 3338 O O   . ASP D 3 32  ? 178.191 238.519 142.479 1.00 105.67 ? 364 ASP D O   1 
ATOM 3339 C CB  . ASP D 3 32  ? 176.558 239.865 145.349 1.00 105.67 ? 364 ASP D CB  1 
ATOM 3340 N N   . TYR D 3 33  ? 176.508 240.017 142.462 1.00 106.16 ? 365 TYR D N   1 
ATOM 3341 C CA  . TYR D 3 33  ? 176.813 240.522 141.130 1.00 106.16 ? 365 TYR D CA  1 
ATOM 3342 C C   . TYR D 3 33  ? 176.904 242.037 141.046 1.00 106.16 ? 365 TYR D C   1 
ATOM 3343 O O   . TYR D 3 33  ? 177.588 242.541 140.147 1.00 106.16 ? 365 TYR D O   1 
ATOM 3344 C CB  . TYR D 3 33  ? 175.765 240.037 140.117 1.00 106.16 ? 365 TYR D CB  1 
ATOM 3345 N N   . SER D 3 34  ? 176.247 242.776 141.934 1.00 107.07 ? 366 SER D N   1 
ATOM 3346 C CA  . SER D 3 34  ? 176.297 244.238 141.924 1.00 107.07 ? 366 SER D CA  1 
ATOM 3347 C C   . SER D 3 34  ? 177.417 244.763 142.816 1.00 107.07 ? 366 SER D C   1 
ATOM 3348 O O   . SER D 3 34  ? 177.204 245.594 143.697 1.00 107.07 ? 366 SER D O   1 
ATOM 3349 C CB  . SER D 3 34  ? 174.947 244.804 142.347 1.00 107.07 ? 366 SER D CB  1 
ATOM 3350 O OG  . SER D 3 34  ? 174.654 244.467 143.692 1.00 107.07 ? 366 SER D OG  1 
ATOM 3351 N N   . VAL D 3 35  ? 178.631 244.275 142.584 1.00 101.70 ? 367 VAL D N   1 
ATOM 3352 C CA  . VAL D 3 35  ? 179.784 244.689 143.372 1.00 101.70 ? 367 VAL D CA  1 
ATOM 3353 C C   . VAL D 3 35  ? 180.376 245.976 142.809 1.00 101.70 ? 367 VAL D C   1 
ATOM 3354 O O   . VAL D 3 35  ? 181.142 246.664 143.483 1.00 101.70 ? 367 VAL D O   1 
ATOM 3355 C CB  . VAL D 3 35  ? 180.847 243.580 143.427 1.00 101.70 ? 367 VAL D CB  1 
ATOM 3356 N N   . SER D 3 43  ? 182.514 246.283 131.916 1.00 96.09  ? 375 SER D N   1 
ATOM 3357 C CA  . SER D 3 43  ? 182.214 245.866 130.553 1.00 96.09  ? 375 SER D CA  1 
ATOM 3358 C C   . SER D 3 43  ? 182.115 244.349 130.455 1.00 96.09  ? 375 SER D C   1 
ATOM 3359 O O   . SER D 3 43  ? 182.669 243.630 131.285 1.00 96.09  ? 375 SER D O   1 
ATOM 3360 C CB  . SER D 3 43  ? 183.278 246.385 129.585 1.00 96.09  ? 375 SER D CB  1 
ATOM 3361 O OG  . SER D 3 43  ? 183.303 247.801 129.567 1.00 96.09  ? 375 SER D OG  1 
ATOM 3362 N N   . THR D 3 44  ? 181.397 243.876 129.434 1.00 97.07  ? 376 THR D N   1 
ATOM 3363 C CA  . THR D 3 44  ? 181.231 242.451 129.145 1.00 97.07  ? 376 THR D CA  1 
ATOM 3364 C C   . THR D 3 44  ? 180.645 241.740 130.374 1.00 97.07  ? 376 THR D C   1 
ATOM 3365 O O   . THR D 3 44  ? 181.294 240.971 131.087 1.00 97.07  ? 376 THR D O   1 
ATOM 3366 C CB  . THR D 3 44  ? 182.558 241.847 128.653 1.00 97.07  ? 376 THR D CB  1 
ATOM 3367 O OG1 . THR D 3 44  ? 182.777 242.263 127.301 1.00 97.07  ? 376 THR D OG1 1 
ATOM 3368 C CG2 . THR D 3 44  ? 182.510 240.322 128.610 1.00 97.07  ? 376 THR D CG2 1 
ATOM 3369 N N   . PHE D 3 45  ? 179.396 242.110 130.659 1.00 100.15 ? 377 PHE D N   1 
ATOM 3370 C CA  . PHE D 3 45  ? 178.655 241.516 131.765 1.00 100.15 ? 377 PHE D CA  1 
ATOM 3371 C C   . PHE D 3 45  ? 178.224 240.084 131.481 1.00 100.15 ? 377 PHE D C   1 
ATOM 3372 O O   . PHE D 3 45  ? 177.744 239.409 132.398 1.00 100.15 ? 377 PHE D O   1 
ATOM 3373 C CB  . PHE D 3 45  ? 177.425 242.371 132.086 1.00 100.15 ? 377 PHE D CB  1 
ATOM 3374 C CG  . PHE D 3 45  ? 176.864 242.146 133.464 1.00 100.15 ? 377 PHE D CG  1 
ATOM 3375 C CD1 . PHE D 3 45  ? 177.544 242.590 134.587 1.00 100.15 ? 377 PHE D CD1 1 
ATOM 3376 C CD2 . PHE D 3 45  ? 175.653 241.495 133.635 1.00 100.15 ? 377 PHE D CD2 1 
ATOM 3377 C CE1 . PHE D 3 45  ? 177.027 242.387 135.854 1.00 100.15 ? 377 PHE D CE1 1 
ATOM 3378 C CE2 . PHE D 3 45  ? 175.133 241.288 134.898 1.00 100.15 ? 377 PHE D CE2 1 
ATOM 3379 C CZ  . PHE D 3 45  ? 175.821 241.734 136.009 1.00 100.15 ? 377 PHE D CZ  1 
ATOM 3380 N N   . LYS D 3 46  ? 178.384 239.612 130.245 1.00 97.09  ? 378 LYS D N   1 
ATOM 3381 C CA  . LYS D 3 46  ? 177.883 238.299 129.860 1.00 97.09  ? 378 LYS D CA  1 
ATOM 3382 C C   . LYS D 3 46  ? 178.530 237.195 130.686 1.00 97.09  ? 378 LYS D C   1 
ATOM 3383 O O   . LYS D 3 46  ? 179.742 237.200 130.921 1.00 97.09  ? 378 LYS D O   1 
ATOM 3384 C CB  . LYS D 3 46  ? 178.127 238.066 128.368 1.00 97.09  ? 378 LYS D CB  1 
ATOM 3385 C CG  . LYS D 3 46  ? 179.574 238.229 127.932 1.00 97.09  ? 378 LYS D CG  1 
ATOM 3386 C CD  . LYS D 3 46  ? 179.697 238.215 126.417 1.00 97.09  ? 378 LYS D CD  1 
ATOM 3387 C CE  . LYS D 3 46  ? 179.578 236.807 125.862 1.00 97.09  ? 378 LYS D CE  1 
ATOM 3388 N NZ  . LYS D 3 46  ? 180.777 235.994 126.195 1.00 97.09  ? 378 LYS D NZ  1 
ATOM 3389 N N   . CYS D 3 47  ? 177.706 236.250 131.134 1.00 93.85  ? 379 CYS D N   1 
ATOM 3390 C CA  . CYS D 3 47  ? 178.144 235.125 131.945 1.00 93.85  ? 379 CYS D CA  1 
ATOM 3391 C C   . CYS D 3 47  ? 177.623 233.838 131.325 1.00 93.85  ? 379 CYS D C   1 
ATOM 3392 O O   . CYS D 3 47  ? 176.532 233.816 130.748 1.00 93.85  ? 379 CYS D O   1 
ATOM 3393 C CB  . CYS D 3 47  ? 177.645 235.255 133.388 1.00 93.85  ? 379 CYS D CB  1 
ATOM 3394 S SG  . CYS D 3 47  ? 178.337 236.659 134.296 1.00 93.85  ? 379 CYS D SG  1 
ATOM 3395 N N   . TYR D 3 48  ? 178.401 232.769 131.446 1.00 87.08  ? 380 TYR D N   1 
ATOM 3396 C CA  . TYR D 3 48  ? 178.062 231.486 130.851 1.00 87.08  ? 380 TYR D CA  1 
ATOM 3397 C C   . TYR D 3 48  ? 177.577 230.510 131.918 1.00 87.08  ? 380 TYR D C   1 
ATOM 3398 O O   . TYR D 3 48  ? 177.659 230.766 133.121 1.00 87.08  ? 380 TYR D O   1 
ATOM 3399 C CB  . TYR D 3 48  ? 179.267 230.899 130.108 1.00 87.08  ? 380 TYR D CB  1 
ATOM 3400 C CG  . TYR D 3 48  ? 179.516 231.493 128.740 1.00 87.08  ? 380 TYR D CG  1 
ATOM 3401 C CD1 . TYR D 3 48  ? 179.178 232.809 128.457 1.00 87.08  ? 380 TYR D CD1 1 
ATOM 3402 C CD2 . TYR D 3 48  ? 180.095 230.736 127.732 1.00 87.08  ? 380 TYR D CD2 1 
ATOM 3403 C CE1 . TYR D 3 48  ? 179.406 233.351 127.210 1.00 87.08  ? 380 TYR D CE1 1 
ATOM 3404 C CE2 . TYR D 3 48  ? 180.327 231.271 126.480 1.00 87.08  ? 380 TYR D CE2 1 
ATOM 3405 C CZ  . TYR D 3 48  ? 179.982 232.579 126.225 1.00 87.08  ? 380 TYR D CZ  1 
ATOM 3406 O OH  . TYR D 3 48  ? 180.211 233.115 124.980 1.00 87.08  ? 380 TYR D OH  1 
ATOM 3407 N N   . GLY D 3 49  ? 177.050 229.381 131.455 1.00 83.19  ? 381 GLY D N   1 
ATOM 3408 C CA  . GLY D 3 49  ? 176.689 228.290 132.339 1.00 83.19  ? 381 GLY D CA  1 
ATOM 3409 C C   . GLY D 3 49  ? 175.463 228.535 133.194 1.00 83.19  ? 381 GLY D C   1 
ATOM 3410 O O   . GLY D 3 49  ? 174.492 227.776 133.127 1.00 83.19  ? 381 GLY D O   1 
ATOM 3411 N N   . VAL D 3 50  ? 175.495 229.589 134.010 1.00 85.48  ? 382 VAL D N   1 
ATOM 3412 C CA  . VAL D 3 50  ? 174.421 229.888 134.945 1.00 85.48  ? 382 VAL D CA  1 
ATOM 3413 C C   . VAL D 3 50  ? 173.987 231.335 134.757 1.00 85.48  ? 382 VAL D C   1 
ATOM 3414 O O   . VAL D 3 50  ? 174.722 232.168 134.224 1.00 85.48  ? 382 VAL D O   1 
ATOM 3415 C CB  . VAL D 3 50  ? 174.835 229.642 136.413 1.00 85.48  ? 382 VAL D CB  1 
ATOM 3416 C CG1 . VAL D 3 50  ? 175.334 228.217 136.597 1.00 85.48  ? 382 VAL D CG1 1 
ATOM 3417 C CG2 . VAL D 3 50  ? 175.894 230.645 136.845 1.00 85.48  ? 382 VAL D CG2 1 
ATOM 3418 N N   . SER D 3 51  ? 172.767 231.621 135.202 1.00 87.50  ? 383 SER D N   1 
ATOM 3419 C CA  . SER D 3 51  ? 172.232 232.966 135.098 1.00 87.50  ? 383 SER D CA  1 
ATOM 3420 C C   . SER D 3 51  ? 172.952 233.902 136.067 1.00 87.50  ? 383 SER D C   1 
ATOM 3421 O O   . SER D 3 51  ? 173.363 233.488 137.154 1.00 87.50  ? 383 SER D O   1 
ATOM 3422 C CB  . SER D 3 51  ? 170.735 232.970 135.393 1.00 87.50  ? 383 SER D CB  1 
ATOM 3423 O OG  . SER D 3 51  ? 170.484 232.665 136.754 1.00 87.50  ? 383 SER D OG  1 
ATOM 3424 N N   . PRO D 3 52  ? 173.125 235.172 135.691 1.00 91.74  ? 384 PRO D N   1 
ATOM 3425 C CA  . PRO D 3 52  ? 173.752 236.130 136.617 1.00 91.74  ? 384 PRO D CA  1 
ATOM 3426 C C   . PRO D 3 52  ? 172.955 236.354 137.888 1.00 91.74  ? 384 PRO D C   1 
ATOM 3427 O O   . PRO D 3 52  ? 173.537 236.754 138.903 1.00 91.74  ? 384 PRO D O   1 
ATOM 3428 C CB  . PRO D 3 52  ? 173.850 237.417 135.784 1.00 91.74  ? 384 PRO D CB  1 
ATOM 3429 C CG  . PRO D 3 52  ? 173.699 236.979 134.361 1.00 91.74  ? 384 PRO D CG  1 
ATOM 3430 C CD  . PRO D 3 52  ? 172.805 235.783 134.392 1.00 91.74  ? 384 PRO D CD  1 
ATOM 3431 N N   . THR D 3 53  ? 171.648 236.111 137.870 1.00 91.79  ? 385 THR D N   1 
ATOM 3432 C CA  . THR D 3 53  ? 170.819 236.299 139.053 1.00 91.79  ? 385 THR D CA  1 
ATOM 3433 C C   . THR D 3 53  ? 170.693 235.000 139.842 1.00 91.79  ? 385 THR D C   1 
ATOM 3434 O O   . THR D 3 53  ? 169.791 234.199 139.597 1.00 91.79  ? 385 THR D O   1 
ATOM 3435 C CB  . THR D 3 53  ? 169.414 236.805 138.682 1.00 91.79  ? 385 THR D CB  1 
ATOM 3436 O OG1 . THR D 3 53  ? 168.759 235.838 137.853 1.00 91.79  ? 385 THR D OG1 1 
ATOM 3437 C CG2 . THR D 3 53  ? 169.505 238.127 137.936 1.00 91.79  ? 385 THR D CG2 1 
ATOM 3438 N N   . LEU D 3 58  ? 171.366 229.034 144.357 1.00 117.24 ? 390 LEU D N   1 
ATOM 3439 C CA  . LEU D 3 58  ? 172.654 229.432 143.803 1.00 117.24 ? 390 LEU D CA  1 
ATOM 3440 C C   . LEU D 3 58  ? 173.801 228.943 144.680 1.00 117.24 ? 390 LEU D C   1 
ATOM 3441 O O   . LEU D 3 58  ? 174.787 229.651 144.878 1.00 117.24 ? 390 LEU D O   1 
ATOM 3442 C CB  . LEU D 3 58  ? 172.723 230.952 143.645 1.00 117.24 ? 390 LEU D CB  1 
ATOM 3443 N N   . CYS D 3 59  ? 173.660 227.729 145.206 1.00 118.61 ? 391 CYS D N   1 
ATOM 3444 C CA  . CYS D 3 59  ? 174.688 227.161 146.067 1.00 118.61 ? 391 CYS D CA  1 
ATOM 3445 C C   . CYS D 3 59  ? 175.960 226.883 145.275 1.00 118.61 ? 391 CYS D C   1 
ATOM 3446 O O   . CYS D 3 59  ? 175.911 226.473 144.112 1.00 118.61 ? 391 CYS D O   1 
ATOM 3447 C CB  . CYS D 3 59  ? 174.184 225.875 146.719 1.00 118.61 ? 391 CYS D CB  1 
ATOM 3448 N N   . PHE D 3 60  ? 177.105 227.111 145.915 1.00 116.86 ? 392 PHE D N   1 
ATOM 3449 C CA  . PHE D 3 60  ? 178.400 226.904 145.286 1.00 116.86 ? 392 PHE D CA  1 
ATOM 3450 C C   . PHE D 3 60  ? 179.319 226.172 146.253 1.00 116.86 ? 392 PHE D C   1 
ATOM 3451 O O   . PHE D 3 60  ? 179.155 226.240 147.473 1.00 116.86 ? 392 PHE D O   1 
ATOM 3452 C CB  . PHE D 3 60  ? 179.036 228.231 144.851 1.00 116.86 ? 392 PHE D CB  1 
ATOM 3453 N N   . THR D 3 61  ? 180.296 225.465 145.687 1.00 119.08 ? 393 THR D N   1 
ATOM 3454 C CA  . THR D 3 61  ? 181.282 224.721 146.460 1.00 119.08 ? 393 THR D CA  1 
ATOM 3455 C C   . THR D 3 61  ? 182.655 225.374 146.442 1.00 119.08 ? 393 THR D C   1 
ATOM 3456 O O   . THR D 3 61  ? 183.241 225.614 147.503 1.00 119.08 ? 393 THR D O   1 
ATOM 3457 C CB  . THR D 3 61  ? 181.387 223.281 145.934 1.00 119.08 ? 393 THR D CB  1 
ATOM 3458 O OG1 . THR D 3 61  ? 180.185 222.566 146.246 1.00 119.08 ? 393 THR D OG1 1 
ATOM 3459 C CG2 . THR D 3 61  ? 182.574 222.566 146.564 1.00 119.08 ? 393 THR D CG2 1 
ATOM 3460 N N   . ASN D 3 62  ? 183.185 225.675 145.259 1.00 118.97 ? 394 ASN D N   1 
ATOM 3461 C CA  . ASN D 3 62  ? 184.484 226.317 145.140 1.00 118.97 ? 394 ASN D CA  1 
ATOM 3462 C C   . ASN D 3 62  ? 184.435 227.324 144.001 1.00 118.97 ? 394 ASN D C   1 
ATOM 3463 O O   . ASN D 3 62  ? 183.654 227.186 143.056 1.00 118.97 ? 394 ASN D O   1 
ATOM 3464 C CB  . ASN D 3 62  ? 185.601 225.292 144.904 1.00 118.97 ? 394 ASN D CB  1 
ATOM 3465 N N   . VAL D 3 63  ? 185.284 228.344 144.101 1.00 116.70 ? 395 VAL D N   1 
ATOM 3466 C CA  . VAL D 3 63  ? 185.379 229.399 143.100 1.00 116.70 ? 395 VAL D CA  1 
ATOM 3467 C C   . VAL D 3 63  ? 186.800 229.421 142.552 1.00 116.70 ? 395 VAL D C   1 
ATOM 3468 O O   . VAL D 3 63  ? 187.768 229.259 143.305 1.00 116.70 ? 395 VAL D O   1 
ATOM 3469 C CB  . VAL D 3 63  ? 184.976 230.772 143.673 1.00 116.70 ? 395 VAL D CB  1 
ATOM 3470 C CG1 . VAL D 3 63  ? 183.560 230.715 144.220 1.00 116.70 ? 395 VAL D CG1 1 
ATOM 3471 C CG2 . VAL D 3 63  ? 185.940 231.217 144.762 1.00 116.70 ? 395 VAL D CG2 1 
ATOM 3472 N N   . TYR D 3 64  ? 186.919 229.586 141.237 1.00 114.68 ? 396 TYR D N   1 
ATOM 3473 C CA  . TYR D 3 64  ? 188.205 229.643 140.547 1.00 114.68 ? 396 TYR D CA  1 
ATOM 3474 C C   . TYR D 3 64  ? 188.233 230.943 139.750 1.00 114.68 ? 396 TYR D C   1 
ATOM 3475 O O   . TYR D 3 64  ? 187.660 231.017 138.661 1.00 114.68 ? 396 TYR D O   1 
ATOM 3476 C CB  . TYR D 3 64  ? 188.392 228.421 139.647 1.00 114.68 ? 396 TYR D CB  1 
ATOM 3477 C CG  . TYR D 3 64  ? 189.804 228.210 139.140 1.00 114.68 ? 396 TYR D CG  1 
ATOM 3478 C CD1 . TYR D 3 64  ? 190.365 229.068 138.202 1.00 114.68 ? 396 TYR D CD1 1 
ATOM 3479 C CD2 . TYR D 3 64  ? 190.572 227.146 139.594 1.00 114.68 ? 396 TYR D CD2 1 
ATOM 3480 C CE1 . TYR D 3 64  ? 191.651 228.876 137.736 1.00 114.68 ? 396 TYR D CE1 1 
ATOM 3481 C CE2 . TYR D 3 64  ? 191.859 226.946 139.133 1.00 114.68 ? 396 TYR D CE2 1 
ATOM 3482 C CZ  . TYR D 3 64  ? 192.393 227.814 138.204 1.00 114.68 ? 396 TYR D CZ  1 
ATOM 3483 O OH  . TYR D 3 64  ? 193.674 227.619 137.742 1.00 114.68 ? 396 TYR D OH  1 
ATOM 3484 N N   . ALA D 3 65  ? 188.882 231.967 140.295 1.00 112.96 ? 397 ALA D N   1 
ATOM 3485 C CA  . ALA D 3 65  ? 188.955 233.285 139.667 1.00 112.96 ? 397 ALA D CA  1 
ATOM 3486 C C   . ALA D 3 65  ? 190.313 233.414 138.980 1.00 112.96 ? 397 ALA D C   1 
ATOM 3487 O O   . ALA D 3 65  ? 191.308 233.788 139.602 1.00 112.96 ? 397 ALA D O   1 
ATOM 3488 C CB  . ALA D 3 65  ? 188.739 234.394 140.692 1.00 112.96 ? 397 ALA D CB  1 
ATOM 3489 N N   . ASP D 3 66  ? 190.345 233.102 137.687 1.00 113.73 ? 398 ASP D N   1 
ATOM 3490 C CA  . ASP D 3 66  ? 191.559 233.223 136.890 1.00 113.73 ? 398 ASP D CA  1 
ATOM 3491 C C   . ASP D 3 66  ? 191.607 234.612 136.266 1.00 113.73 ? 398 ASP D C   1 
ATOM 3492 O O   . ASP D 3 66  ? 190.722 234.977 135.485 1.00 113.73 ? 398 ASP D O   1 
ATOM 3493 C CB  . ASP D 3 66  ? 191.609 232.142 135.812 1.00 113.73 ? 398 ASP D CB  1 
ATOM 3494 N N   . SER D 3 67  ? 192.636 235.380 136.611 1.00 116.08 ? 399 SER D N   1 
ATOM 3495 C CA  . SER D 3 67  ? 192.782 236.759 136.171 1.00 116.08 ? 399 SER D CA  1 
ATOM 3496 C C   . SER D 3 67  ? 193.981 236.889 135.241 1.00 116.08 ? 399 SER D C   1 
ATOM 3497 O O   . SER D 3 67  ? 195.032 236.287 135.479 1.00 116.08 ? 399 SER D O   1 
ATOM 3498 C CB  . SER D 3 67  ? 192.950 237.699 137.368 1.00 116.08 ? 399 SER D CB  1 
ATOM 3499 O OG  . SER D 3 67  ? 194.081 237.338 138.142 1.00 116.08 ? 399 SER D OG  1 
ATOM 3500 N N   . PHE D 3 68  ? 193.817 237.680 134.185 1.00 112.91 ? 400 PHE D N   1 
ATOM 3501 C CA  . PHE D 3 68  ? 194.884 237.914 133.219 1.00 112.91 ? 400 PHE D CA  1 
ATOM 3502 C C   . PHE D 3 68  ? 194.550 239.176 132.435 1.00 112.91 ? 400 PHE D C   1 
ATOM 3503 O O   . PHE D 3 68  ? 193.540 239.837 132.688 1.00 112.91 ? 400 PHE D O   1 
ATOM 3504 C CB  . PHE D 3 68  ? 195.078 236.698 132.307 1.00 112.91 ? 400 PHE D CB  1 
ATOM 3505 C CG  . PHE D 3 68  ? 193.798 236.152 131.744 1.00 112.91 ? 400 PHE D CG  1 
ATOM 3506 C CD1 . PHE D 3 68  ? 193.113 235.146 132.405 1.00 112.91 ? 400 PHE D CD1 1 
ATOM 3507 C CD2 . PHE D 3 68  ? 193.278 236.641 130.559 1.00 112.91 ? 400 PHE D CD2 1 
ATOM 3508 C CE1 . PHE D 3 68  ? 191.937 234.638 131.895 1.00 112.91 ? 400 PHE D CE1 1 
ATOM 3509 C CE2 . PHE D 3 68  ? 192.099 236.135 130.046 1.00 112.91 ? 400 PHE D CE2 1 
ATOM 3510 C CZ  . PHE D 3 68  ? 191.430 235.134 130.714 1.00 112.91 ? 400 PHE D CZ  1 
ATOM 3511 N N   . VAL D 3 69  ? 195.418 239.521 131.488 1.00 113.42 ? 401 VAL D N   1 
ATOM 3512 C CA  . VAL D 3 69  ? 195.228 240.695 130.645 1.00 113.42 ? 401 VAL D CA  1 
ATOM 3513 C C   . VAL D 3 69  ? 195.414 240.292 129.188 1.00 113.42 ? 401 VAL D C   1 
ATOM 3514 O O   . VAL D 3 69  ? 196.399 239.632 128.839 1.00 113.42 ? 401 VAL D O   1 
ATOM 3515 C CB  . VAL D 3 69  ? 196.180 241.845 131.036 1.00 113.42 ? 401 VAL D CB  1 
ATOM 3516 C CG1 . VAL D 3 69  ? 197.640 241.449 130.861 1.00 113.42 ? 401 VAL D CG1 1 
ATOM 3517 C CG2 . VAL D 3 69  ? 195.864 243.092 130.227 1.00 113.42 ? 401 VAL D CG2 1 
ATOM 3518 N N   . ILE D 3 70  ? 194.444 240.655 128.348 1.00 114.58 ? 402 ILE D N   1 
ATOM 3519 C CA  . ILE D 3 70  ? 194.496 240.399 126.914 1.00 114.58 ? 402 ILE D CA  1 
ATOM 3520 C C   . ILE D 3 70  ? 193.902 241.608 126.207 1.00 114.58 ? 402 ILE D C   1 
ATOM 3521 O O   . ILE D 3 70  ? 192.961 242.236 126.700 1.00 114.58 ? 402 ILE D O   1 
ATOM 3522 C CB  . ILE D 3 70  ? 193.743 239.105 126.513 1.00 114.58 ? 402 ILE D CB  1 
ATOM 3523 C CG1 . ILE D 3 70  ? 194.330 237.880 127.214 1.00 114.58 ? 402 ILE D CG1 1 
ATOM 3524 C CG2 . ILE D 3 70  ? 193.799 238.883 125.015 1.00 114.58 ? 402 ILE D CG2 1 
ATOM 3525 C CD1 . ILE D 3 70  ? 193.581 236.604 126.918 1.00 114.58 ? 402 ILE D CD1 1 
ATOM 3526 N N   . ARG D 3 71  ? 194.462 241.940 125.046 1.00 118.80 ? 403 ARG D N   1 
ATOM 3527 C CA  . ARG D 3 71  ? 193.978 243.073 124.275 1.00 118.80 ? 403 ARG D CA  1 
ATOM 3528 C C   . ARG D 3 71  ? 192.515 242.873 123.879 1.00 118.80 ? 403 ARG D C   1 
ATOM 3529 O O   . ARG D 3 71  ? 191.953 241.779 123.975 1.00 118.80 ? 403 ARG D O   1 
ATOM 3530 C CB  . ARG D 3 71  ? 194.841 243.280 123.032 1.00 118.80 ? 403 ARG D CB  1 
ATOM 3531 N N   . GLY D 3 72  ? 191.897 243.960 123.416 1.00 124.96 ? 404 GLY D N   1 
ATOM 3532 C CA  . GLY D 3 72  ? 190.484 243.943 123.077 1.00 124.96 ? 404 GLY D CA  1 
ATOM 3533 C C   . GLY D 3 72  ? 190.152 243.229 121.783 1.00 124.96 ? 404 GLY D C   1 
ATOM 3534 O O   . GLY D 3 72  ? 188.966 243.045 121.487 1.00 124.96 ? 404 GLY D O   1 
ATOM 3535 N N   . ASP D 3 73  ? 191.160 242.832 121.009 1.00 126.19 ? 405 ASP D N   1 
ATOM 3536 C CA  . ASP D 3 73  ? 190.956 242.072 119.782 1.00 126.19 ? 405 ASP D CA  1 
ATOM 3537 C C   . ASP D 3 73  ? 190.986 240.568 120.023 1.00 126.19 ? 405 ASP D C   1 
ATOM 3538 O O   . ASP D 3 73  ? 190.119 239.842 119.527 1.00 126.19 ? 405 ASP D O   1 
ATOM 3539 C CB  . ASP D 3 73  ? 192.015 242.456 118.742 1.00 126.19 ? 405 ASP D CB  1 
ATOM 3540 N N   . GLU D 3 74  ? 191.970 240.083 120.782 1.00 121.83 ? 406 GLU D N   1 
ATOM 3541 C CA  . GLU D 3 74  ? 192.071 238.658 121.066 1.00 121.83 ? 406 GLU D CA  1 
ATOM 3542 C C   . GLU D 3 74  ? 191.098 238.197 122.142 1.00 121.83 ? 406 GLU D C   1 
ATOM 3543 O O   . GLU D 3 74  ? 190.951 236.986 122.337 1.00 121.83 ? 406 GLU D O   1 
ATOM 3544 C CB  . GLU D 3 74  ? 193.501 238.305 121.477 1.00 121.83 ? 406 GLU D CB  1 
ATOM 3545 N N   . VAL D 3 75  ? 190.439 239.122 122.845 1.00 120.48 ? 407 VAL D N   1 
ATOM 3546 C CA  . VAL D 3 75  ? 189.465 238.736 123.860 1.00 120.48 ? 407 VAL D CA  1 
ATOM 3547 C C   . VAL D 3 75  ? 188.248 238.064 123.237 1.00 120.48 ? 407 VAL D C   1 
ATOM 3548 O O   . VAL D 3 75  ? 187.544 237.307 123.916 1.00 120.48 ? 407 VAL D O   1 
ATOM 3549 C CB  . VAL D 3 75  ? 189.057 239.961 124.702 1.00 120.48 ? 407 VAL D CB  1 
ATOM 3550 C CG1 . VAL D 3 75  ? 188.224 240.930 123.878 1.00 120.48 ? 407 VAL D CG1 1 
ATOM 3551 C CG2 . VAL D 3 75  ? 188.313 239.532 125.959 1.00 120.48 ? 407 VAL D CG2 1 
ATOM 3552 N N   . ARG D 3 76  ? 187.987 238.310 121.950 1.00 122.74 ? 408 ARG D N   1 
ATOM 3553 C CA  . ARG D 3 76  ? 186.871 237.659 121.273 1.00 122.74 ? 408 ARG D CA  1 
ATOM 3554 C C   . ARG D 3 76  ? 187.067 236.154 121.158 1.00 122.74 ? 408 ARG D C   1 
ATOM 3555 O O   . ARG D 3 76  ? 186.092 235.429 120.932 1.00 122.74 ? 408 ARG D O   1 
ATOM 3556 C CB  . ARG D 3 76  ? 186.674 238.265 119.883 1.00 122.74 ? 408 ARG D CB  1 
ATOM 3557 N N   . GLN D 3 77  ? 188.299 235.670 121.307 1.00 123.68 ? 409 GLN D N   1 
ATOM 3558 C CA  . GLN D 3 77  ? 188.574 234.242 121.230 1.00 123.68 ? 409 GLN D CA  1 
ATOM 3559 C C   . GLN D 3 77  ? 188.355 233.522 122.554 1.00 123.68 ? 409 GLN D C   1 
ATOM 3560 O O   . GLN D 3 77  ? 188.511 232.298 122.605 1.00 123.68 ? 409 GLN D O   1 
ATOM 3561 C CB  . GLN D 3 77  ? 190.009 234.008 120.752 1.00 123.68 ? 409 GLN D CB  1 
ATOM 3562 N N   . ILE D 3 78  ? 187.996 234.240 123.617 1.00 120.86 ? 410 ILE D N   1 
ATOM 3563 C CA  . ILE D 3 78  ? 187.769 233.615 124.915 1.00 120.86 ? 410 ILE D CA  1 
ATOM 3564 C C   . ILE D 3 78  ? 186.330 233.123 124.978 1.00 120.86 ? 410 ILE D C   1 
ATOM 3565 O O   . ILE D 3 78  ? 185.453 233.800 125.525 1.00 120.86 ? 410 ILE D O   1 
ATOM 3566 C CB  . ILE D 3 78  ? 188.070 234.587 126.070 1.00 120.86 ? 410 ILE D CB  1 
ATOM 3567 C CG1 . ILE D 3 78  ? 189.356 235.367 125.796 1.00 120.86 ? 410 ILE D CG1 1 
ATOM 3568 C CG2 . ILE D 3 78  ? 188.179 233.831 127.383 1.00 120.86 ? 410 ILE D CG2 1 
ATOM 3569 C CD1 . ILE D 3 78  ? 190.609 234.534 125.907 1.00 120.86 ? 410 ILE D CD1 1 
ATOM 3570 N N   . ALA D 3 79  ? 186.083 231.935 124.424 1.00 119.65 ? 411 ALA D N   1 
ATOM 3571 C CA  . ALA D 3 79  ? 184.751 231.346 124.383 1.00 119.65 ? 411 ALA D CA  1 
ATOM 3572 C C   . ALA D 3 79  ? 184.845 229.877 123.990 1.00 119.65 ? 411 ALA D C   1 
ATOM 3573 O O   . ALA D 3 79  ? 185.685 229.510 123.159 1.00 119.65 ? 411 ALA D O   1 
ATOM 3574 C CB  . ALA D 3 79  ? 183.852 232.100 123.401 1.00 119.65 ? 411 ALA D CB  1 
ATOM 3575 N N   . PRO D 3 80  ? 184.017 229.007 124.574 1.00 115.47 ? 412 PRO D N   1 
ATOM 3576 C CA  . PRO D 3 80  ? 184.030 227.597 124.147 1.00 115.47 ? 412 PRO D CA  1 
ATOM 3577 C C   . PRO D 3 80  ? 183.718 227.413 122.672 1.00 115.47 ? 412 PRO D C   1 
ATOM 3578 O O   . PRO D 3 80  ? 184.293 226.528 122.026 1.00 115.47 ? 412 PRO D O   1 
ATOM 3579 C CB  . PRO D 3 80  ? 182.962 226.950 125.039 1.00 115.47 ? 412 PRO D CB  1 
ATOM 3580 C CG  . PRO D 3 80  ? 182.834 227.853 126.217 1.00 115.47 ? 412 PRO D CG  1 
ATOM 3581 C CD  . PRO D 3 80  ? 183.154 229.237 125.745 1.00 115.47 ? 412 PRO D CD  1 
ATOM 3582 N N   . GLY D 3 81  ? 182.818 228.230 122.115 1.00 122.09 ? 413 GLY D N   1 
ATOM 3583 C CA  . GLY D 3 81  ? 182.470 228.106 120.711 1.00 122.09 ? 413 GLY D CA  1 
ATOM 3584 C C   . GLY D 3 81  ? 183.448 228.754 119.755 1.00 122.09 ? 413 GLY D C   1 
ATOM 3585 O O   . GLY D 3 81  ? 183.535 228.332 118.597 1.00 122.09 ? 413 GLY D O   1 
ATOM 3586 N N   . GLN D 3 82  ? 184.184 229.767 120.207 1.00 125.07 ? 414 GLN D N   1 
ATOM 3587 C CA  . GLN D 3 82  ? 185.163 230.463 119.380 1.00 125.07 ? 414 GLN D CA  1 
ATOM 3588 C C   . GLN D 3 82  ? 186.558 230.067 119.849 1.00 125.07 ? 414 GLN D C   1 
ATOM 3589 O O   . GLN D 3 82  ? 186.989 230.460 120.938 1.00 125.07 ? 414 GLN D O   1 
ATOM 3590 C CB  . GLN D 3 82  ? 184.965 231.975 119.457 1.00 125.07 ? 414 GLN D CB  1 
ATOM 3591 N N   . THR D 3 83  ? 187.265 229.301 119.023 1.00 129.88 ? 415 THR D N   1 
ATOM 3592 C CA  . THR D 3 83  ? 188.589 228.794 119.354 1.00 129.88 ? 415 THR D CA  1 
ATOM 3593 C C   . THR D 3 83  ? 189.622 229.450 118.451 1.00 129.88 ? 415 THR D C   1 
ATOM 3594 O O   . THR D 3 83  ? 189.412 229.560 117.238 1.00 129.88 ? 415 THR D O   1 
ATOM 3595 C CB  . THR D 3 83  ? 188.653 227.272 119.209 1.00 129.88 ? 415 THR D CB  1 
ATOM 3596 O OG1 . THR D 3 83  ? 187.989 226.877 118.003 1.00 129.88 ? 415 THR D OG1 1 
ATOM 3597 C CG2 . THR D 3 83  ? 187.982 226.597 120.396 1.00 129.88 ? 415 THR D CG2 1 
ATOM 3598 N N   . GLY D 3 84  ? 190.731 229.881 119.045 1.00 136.37 ? 416 GLY D N   1 
ATOM 3599 C CA  . GLY D 3 84  ? 191.810 230.504 118.309 1.00 136.37 ? 416 GLY D CA  1 
ATOM 3600 C C   . GLY D 3 84  ? 193.129 230.226 118.994 1.00 136.37 ? 416 GLY D C   1 
ATOM 3601 O O   . GLY D 3 84  ? 193.184 229.573 120.037 1.00 136.37 ? 416 GLY D O   1 
ATOM 3602 N N   . LYS D 3 85  ? 194.206 230.732 118.388 1.00 140.88 ? 417 LYS D N   1 
ATOM 3603 C CA  . LYS D 3 85  ? 195.538 230.517 118.944 1.00 140.88 ? 417 LYS D CA  1 
ATOM 3604 C C   . LYS D 3 85  ? 195.655 231.121 120.337 1.00 140.88 ? 417 LYS D C   1 
ATOM 3605 O O   . LYS D 3 85  ? 196.177 230.486 121.261 1.00 140.88 ? 417 LYS D O   1 
ATOM 3606 C CB  . LYS D 3 85  ? 196.596 231.105 118.008 1.00 140.88 ? 417 LYS D CB  1 
ATOM 3607 N N   . ILE D 3 86  ? 195.148 232.345 120.512 1.00 136.63 ? 418 ILE D N   1 
ATOM 3608 C CA  . ILE D 3 86  ? 195.218 233.020 121.802 1.00 136.63 ? 418 ILE D CA  1 
ATOM 3609 C C   . ILE D 3 86  ? 194.446 232.270 122.876 1.00 136.63 ? 418 ILE D C   1 
ATOM 3610 O O   . ILE D 3 86  ? 194.706 232.457 124.069 1.00 136.63 ? 418 ILE D O   1 
ATOM 3611 C CB  . ILE D 3 86  ? 194.707 234.469 121.672 1.00 136.63 ? 418 ILE D CB  1 
ATOM 3612 N N   . ALA D 3 87  ? 193.493 231.427 122.483 1.00 136.37 ? 419 ALA D N   1 
ATOM 3613 C CA  . ALA D 3 87  ? 192.746 230.600 123.421 1.00 136.37 ? 419 ALA D CA  1 
ATOM 3614 C C   . ALA D 3 87  ? 193.243 229.162 123.471 1.00 136.37 ? 419 ALA D C   1 
ATOM 3615 O O   . ALA D 3 87  ? 193.264 228.557 124.546 1.00 136.37 ? 419 ALA D O   1 
ATOM 3616 C CB  . ALA D 3 87  ? 191.256 230.610 123.067 1.00 136.37 ? 419 ALA D CB  1 
ATOM 3617 N N   . ASP D 3 88  ? 193.649 228.597 122.332 1.00 141.76 ? 420 ASP D N   1 
ATOM 3618 C CA  . ASP D 3 88  ? 194.120 227.218 122.320 1.00 141.76 ? 420 ASP D CA  1 
ATOM 3619 C C   . ASP D 3 88  ? 195.520 227.072 122.900 1.00 141.76 ? 420 ASP D C   1 
ATOM 3620 O O   . ASP D 3 88  ? 195.922 225.952 123.233 1.00 141.76 ? 420 ASP D O   1 
ATOM 3621 C CB  . ASP D 3 88  ? 194.091 226.660 120.896 1.00 141.76 ? 420 ASP D CB  1 
ATOM 3622 N N   . TYR D 3 89  ? 196.271 228.168 123.031 1.00 145.48 ? 421 TYR D N   1 
ATOM 3623 C CA  . TYR D 3 89  ? 197.643 228.094 123.509 1.00 145.48 ? 421 TYR D CA  1 
ATOM 3624 C C   . TYR D 3 89  ? 197.849 228.664 124.905 1.00 145.48 ? 421 TYR D C   1 
ATOM 3625 O O   . TYR D 3 89  ? 198.818 228.281 125.568 1.00 145.48 ? 421 TYR D O   1 
ATOM 3626 C CB  . TYR D 3 89  ? 198.582 228.818 122.533 1.00 145.48 ? 421 TYR D CB  1 
ATOM 3627 C CG  . TYR D 3 89  ? 198.709 228.124 121.196 1.00 145.48 ? 421 TYR D CG  1 
ATOM 3628 C CD1 . TYR D 3 89  ? 198.968 226.762 121.122 1.00 145.48 ? 421 TYR D CD1 1 
ATOM 3629 C CD2 . TYR D 3 89  ? 198.557 228.828 120.010 1.00 145.48 ? 421 TYR D CD2 1 
ATOM 3630 C CE1 . TYR D 3 89  ? 199.080 226.121 119.903 1.00 145.48 ? 421 TYR D CE1 1 
ATOM 3631 C CE2 . TYR D 3 89  ? 198.665 228.195 118.786 1.00 145.48 ? 421 TYR D CE2 1 
ATOM 3632 C CZ  . TYR D 3 89  ? 198.928 226.843 118.737 1.00 145.48 ? 421 TYR D CZ  1 
ATOM 3633 O OH  . TYR D 3 89  ? 199.039 226.209 117.520 1.00 145.48 ? 421 TYR D OH  1 
ATOM 3634 N N   . ASN D 3 90  ? 196.977 229.557 125.368 1.00 136.40 ? 422 ASN D N   1 
ATOM 3635 C CA  . ASN D 3 90  ? 197.127 230.175 126.679 1.00 136.40 ? 422 ASN D CA  1 
ATOM 3636 C C   . ASN D 3 90  ? 196.017 229.768 127.641 1.00 136.40 ? 422 ASN D C   1 
ATOM 3637 O O   . ASN D 3 90  ? 196.299 229.254 128.727 1.00 136.40 ? 422 ASN D O   1 
ATOM 3638 C CB  . ASN D 3 90  ? 197.176 231.702 126.538 1.00 136.40 ? 422 ASN D CB  1 
ATOM 3639 C CG  . ASN D 3 90  ? 198.582 232.218 126.310 1.00 136.40 ? 422 ASN D CG  1 
ATOM 3640 O OD1 . ASN D 3 90  ? 199.519 231.441 126.131 1.00 136.40 ? 422 ASN D OD1 1 
ATOM 3641 N ND2 . ASN D 3 90  ? 198.736 233.537 126.317 1.00 136.40 ? 422 ASN D ND2 1 
ATOM 3642 N N   . TYR D 3 91  ? 194.757 229.980 127.270 1.00 124.87 ? 423 TYR D N   1 
ATOM 3643 C CA  . TYR D 3 91  ? 193.639 229.668 128.158 1.00 124.87 ? 423 TYR D CA  1 
ATOM 3644 C C   . TYR D 3 91  ? 192.441 229.278 127.306 1.00 124.87 ? 423 TYR D C   1 
ATOM 3645 O O   . TYR D 3 91  ? 191.837 230.135 126.656 1.00 124.87 ? 423 TYR D O   1 
ATOM 3646 C CB  . TYR D 3 91  ? 193.306 230.854 129.059 1.00 124.87 ? 423 TYR D CB  1 
ATOM 3647 C CG  . TYR D 3 91  ? 192.172 230.581 130.019 1.00 124.87 ? 423 TYR D CG  1 
ATOM 3648 C CD1 . TYR D 3 91  ? 192.268 229.569 130.963 1.00 124.87 ? 423 TYR D CD1 1 
ATOM 3649 C CD2 . TYR D 3 91  ? 191.008 231.335 129.982 1.00 124.87 ? 423 TYR D CD2 1 
ATOM 3650 C CE1 . TYR D 3 91  ? 191.237 229.313 131.843 1.00 124.87 ? 423 TYR D CE1 1 
ATOM 3651 C CE2 . TYR D 3 91  ? 189.970 231.085 130.858 1.00 124.87 ? 423 TYR D CE2 1 
ATOM 3652 C CZ  . TYR D 3 91  ? 190.091 230.073 131.786 1.00 124.87 ? 423 TYR D CZ  1 
ATOM 3653 O OH  . TYR D 3 91  ? 189.064 229.816 132.663 1.00 124.87 ? 423 TYR D OH  1 
ATOM 3654 N N   . LYS D 3 92  ? 192.102 227.992 127.309 1.00 120.15 ? 424 LYS D N   1 
ATOM 3655 C CA  . LYS D 3 92  ? 190.949 227.480 126.580 1.00 120.15 ? 424 LYS D CA  1 
ATOM 3656 C C   . LYS D 3 92  ? 189.837 227.177 127.575 1.00 120.15 ? 424 LYS D C   1 
ATOM 3657 O O   . LYS D 3 92  ? 190.051 226.444 128.547 1.00 120.15 ? 424 LYS D O   1 
ATOM 3658 C CB  . LYS D 3 92  ? 191.316 226.229 125.783 1.00 120.15 ? 424 LYS D CB  1 
ATOM 3659 N N   . LEU D 3 93  ? 188.661 227.739 127.333 1.00 112.70 ? 425 LEU D N   1 
ATOM 3660 C CA  . LEU D 3 93  ? 187.540 227.536 128.241 1.00 112.70 ? 425 LEU D CA  1 
ATOM 3661 C C   . LEU D 3 93  ? 187.017 226.110 128.108 1.00 112.70 ? 425 LEU D C   1 
ATOM 3662 O O   . LEU D 3 93  ? 186.717 225.666 126.993 1.00 112.70 ? 425 LEU D O   1 
ATOM 3663 C CB  . LEU D 3 93  ? 186.430 228.542 127.951 1.00 112.70 ? 425 LEU D CB  1 
ATOM 3664 C CG  . LEU D 3 93  ? 186.487 229.826 128.782 1.00 112.70 ? 425 LEU D CG  1 
ATOM 3665 C CD1 . LEU D 3 93  ? 185.326 230.746 128.436 1.00 112.70 ? 425 LEU D CD1 1 
ATOM 3666 C CD2 . LEU D 3 93  ? 186.504 229.506 130.269 1.00 112.70 ? 425 LEU D CD2 1 
ATOM 3667 N N   . PRO D 3 94  ? 186.900 225.365 129.204 1.00 109.13 ? 426 PRO D N   1 
ATOM 3668 C CA  . PRO D 3 94  ? 186.464 223.969 129.104 1.00 109.13 ? 426 PRO D CA  1 
ATOM 3669 C C   . PRO D 3 94  ? 185.018 223.856 128.653 1.00 109.13 ? 426 PRO D C   1 
ATOM 3670 O O   . PRO D 3 94  ? 184.196 224.747 128.878 1.00 109.13 ? 426 PRO D O   1 
ATOM 3671 C CB  . PRO D 3 94  ? 186.641 223.440 130.532 1.00 109.13 ? 426 PRO D CB  1 
ATOM 3672 C CG  . PRO D 3 94  ? 186.530 224.653 131.391 1.00 109.13 ? 426 PRO D CG  1 
ATOM 3673 C CD  . PRO D 3 94  ? 187.137 225.775 130.598 1.00 109.13 ? 426 PRO D CD  1 
ATOM 3674 N N   . ASP D 3 95  ? 184.715 222.734 128.004 1.00 103.40 ? 427 ASP D N   1 
ATOM 3675 C CA  . ASP D 3 95  ? 183.351 222.451 127.592 1.00 103.40 ? 427 ASP D CA  1 
ATOM 3676 C C   . ASP D 3 95  ? 182.466 222.227 128.814 1.00 103.40 ? 427 ASP D C   1 
ATOM 3677 O O   . ASP D 3 95  ? 182.938 221.880 129.901 1.00 103.40 ? 427 ASP D O   1 
ATOM 3678 C CB  . ASP D 3 95  ? 183.307 221.228 126.676 1.00 103.40 ? 427 ASP D CB  1 
ATOM 3679 N N   . ASP D 3 96  ? 181.162 222.432 128.620 1.00 94.23  ? 428 ASP D N   1 
ATOM 3680 C CA  . ASP D 3 96  ? 180.189 222.388 129.712 1.00 94.23  ? 428 ASP D CA  1 
ATOM 3681 C C   . ASP D 3 96  ? 180.589 223.351 130.828 1.00 94.23  ? 428 ASP D C   1 
ATOM 3682 O O   . ASP D 3 96  ? 180.523 223.026 132.016 1.00 94.23  ? 428 ASP D O   1 
ATOM 3683 C CB  . ASP D 3 96  ? 180.017 220.965 130.247 1.00 94.23  ? 428 ASP D CB  1 
ATOM 3684 N N   . PHE D 3 97  ? 181.019 224.546 130.433 1.00 95.37  ? 429 PHE D N   1 
ATOM 3685 C CA  . PHE D 3 97  ? 181.458 225.552 131.389 1.00 95.37  ? 429 PHE D CA  1 
ATOM 3686 C C   . PHE D 3 97  ? 180.295 226.005 132.263 1.00 95.37  ? 429 PHE D C   1 
ATOM 3687 O O   . PHE D 3 97  ? 179.184 226.236 131.778 1.00 95.37  ? 429 PHE D O   1 
ATOM 3688 C CB  . PHE D 3 97  ? 182.062 226.746 130.652 1.00 95.37  ? 429 PHE D CB  1 
ATOM 3689 C CG  . PHE D 3 97  ? 182.786 227.709 131.545 1.00 95.37  ? 429 PHE D CG  1 
ATOM 3690 C CD1 . PHE D 3 97  ? 183.463 227.260 132.665 1.00 95.37  ? 429 PHE D CD1 1 
ATOM 3691 C CD2 . PHE D 3 97  ? 182.797 229.063 131.259 1.00 95.37  ? 429 PHE D CD2 1 
ATOM 3692 C CE1 . PHE D 3 97  ? 184.132 228.144 133.486 1.00 95.37  ? 429 PHE D CE1 1 
ATOM 3693 C CE2 . PHE D 3 97  ? 183.464 229.952 132.077 1.00 95.37  ? 429 PHE D CE2 1 
ATOM 3694 C CZ  . PHE D 3 97  ? 184.133 229.492 133.191 1.00 95.37  ? 429 PHE D CZ  1 
ATOM 3695 N N   . THR D 3 98  ? 180.557 226.131 133.563 1.00 95.46  ? 430 THR D N   1 
ATOM 3696 C CA  . THR D 3 98  ? 179.548 226.529 134.537 1.00 95.46  ? 430 THR D CA  1 
ATOM 3697 C C   . THR D 3 98  ? 179.896 227.863 135.187 1.00 95.46  ? 430 THR D C   1 
ATOM 3698 O O   . THR D 3 98  ? 179.449 228.153 136.298 1.00 95.46  ? 430 THR D O   1 
ATOM 3699 C CB  . THR D 3 98  ? 179.374 225.455 135.611 1.00 95.46  ? 430 THR D CB  1 
ATOM 3700 O OG1 . THR D 3 98  ? 180.403 225.596 136.598 1.00 95.46  ? 430 THR D OG1 1 
ATOM 3701 C CG2 . THR D 3 98  ? 179.462 224.066 135.002 1.00 95.46  ? 430 THR D CG2 1 
ATOM 3702 N N   . GLY D 3 99  ? 180.691 228.688 134.505 1.00 97.94  ? 431 GLY D N   1 
ATOM 3703 C CA  . GLY D 3 99  ? 181.204 229.911 135.084 1.00 97.94  ? 431 GLY D CA  1 
ATOM 3704 C C   . GLY D 3 99  ? 180.950 231.118 134.199 1.00 97.94  ? 431 GLY D C   1 
ATOM 3705 O O   . GLY D 3 99  ? 180.422 231.009 133.092 1.00 97.94  ? 431 GLY D O   1 
ATOM 3706 N N   . CYS D 3 100 ? 181.361 232.270 134.717 1.00 101.66 ? 432 CYS D N   1 
ATOM 3707 C CA  . CYS D 3 100 ? 181.159 233.563 134.081 1.00 101.66 ? 432 CYS D CA  1 
ATOM 3708 C C   . CYS D 3 100 ? 182.506 234.205 133.773 1.00 101.66 ? 432 CYS D C   1 
ATOM 3709 O O   . CYS D 3 100 ? 183.563 233.695 134.147 1.00 101.66 ? 432 CYS D O   1 
ATOM 3710 C CB  . CYS D 3 100 ? 180.317 234.481 134.976 1.00 101.66 ? 432 CYS D CB  1 
ATOM 3711 S SG  . CYS D 3 100 ? 180.309 236.215 134.487 1.00 101.66 ? 432 CYS D SG  1 
ATOM 3712 N N   . VAL D 3 101 ? 182.461 235.343 133.086 1.00 100.29 ? 433 VAL D N   1 
ATOM 3713 C CA  . VAL D 3 101 ? 183.675 236.056 132.698 1.00 100.29 ? 433 VAL D CA  1 
ATOM 3714 C C   . VAL D 3 101 ? 183.373 237.548 132.649 1.00 100.29 ? 433 VAL D C   1 
ATOM 3715 O O   . VAL D 3 101 ? 182.296 237.965 132.214 1.00 100.29 ? 433 VAL D O   1 
ATOM 3716 C CB  . VAL D 3 101 ? 184.223 235.532 131.351 1.00 100.29 ? 433 VAL D CB  1 
ATOM 3717 C CG1 . VAL D 3 101 ? 183.246 235.810 130.217 1.00 100.29 ? 433 VAL D CG1 1 
ATOM 3718 C CG2 . VAL D 3 101 ? 185.583 236.140 131.053 1.00 100.29 ? 433 VAL D CG2 1 
ATOM 3719 N N   . ILE D 3 102 ? 184.325 238.353 133.118 1.00 102.02 ? 434 ILE D N   1 
ATOM 3720 C CA  . ILE D 3 102 ? 184.197 239.806 133.155 1.00 102.02 ? 434 ILE D CA  1 
ATOM 3721 C C   . ILE D 3 102 ? 185.473 240.405 132.580 1.00 102.02 ? 434 ILE D C   1 
ATOM 3722 O O   . ILE D 3 102 ? 186.569 240.146 133.091 1.00 102.02 ? 434 ILE D O   1 
ATOM 3723 C CB  . ILE D 3 102 ? 183.954 240.326 134.583 1.00 102.02 ? 434 ILE D CB  1 
ATOM 3724 C CG1 . ILE D 3 102 ? 182.561 239.923 135.075 1.00 102.02 ? 434 ILE D CG1 1 
ATOM 3725 C CG2 . ILE D 3 102 ? 184.134 241.837 134.642 1.00 102.02 ? 434 ILE D CG2 1 
ATOM 3726 C CD1 . ILE D 3 102 ? 181.424 240.529 134.281 1.00 102.02 ? 434 ILE D CD1 1 
ATOM 3727 N N   . ALA D 3 103 ? 185.334 241.213 131.531 1.00 102.19 ? 435 ALA D N   1 
ATOM 3728 C CA  . ALA D 3 103 ? 186.465 241.873 130.885 1.00 102.19 ? 435 ALA D CA  1 
ATOM 3729 C C   . ALA D 3 103 ? 186.264 243.379 130.984 1.00 102.19 ? 435 ALA D C   1 
ATOM 3730 O O   . ALA D 3 103 ? 185.342 243.926 130.370 1.00 102.19 ? 435 ALA D O   1 
ATOM 3731 C CB  . ALA D 3 103 ? 186.598 241.432 129.429 1.00 102.19 ? 435 ALA D CB  1 
ATOM 3732 N N   . TRP D 3 104 ? 187.126 244.051 131.744 1.00 108.83 ? 436 TRP D N   1 
ATOM 3733 C CA  . TRP D 3 104 ? 186.998 245.484 131.965 1.00 108.83 ? 436 TRP D CA  1 
ATOM 3734 C C   . TRP D 3 104 ? 188.188 246.230 131.378 1.00 108.83 ? 436 TRP D C   1 
ATOM 3735 O O   . TRP D 3 104 ? 189.294 245.689 131.260 1.00 108.83 ? 436 TRP D O   1 
ATOM 3736 C CB  . TRP D 3 104 ? 186.859 245.815 133.458 1.00 108.83 ? 436 TRP D CB  1 
ATOM 3737 C CG  . TRP D 3 104 ? 188.120 245.673 134.248 1.00 108.83 ? 436 TRP D CG  1 
ATOM 3738 C CD1 . TRP D 3 104 ? 189.132 246.581 134.354 1.00 108.83 ? 436 TRP D CD1 1 
ATOM 3739 C CD2 . TRP D 3 104 ? 188.498 244.555 135.057 1.00 108.83 ? 436 TRP D CD2 1 
ATOM 3740 N NE1 . TRP D 3 104 ? 190.120 246.095 135.174 1.00 108.83 ? 436 TRP D NE1 1 
ATOM 3741 C CE2 . TRP D 3 104 ? 189.754 244.853 135.619 1.00 108.83 ? 436 TRP D CE2 1 
ATOM 3742 C CE3 . TRP D 3 104 ? 187.898 243.331 135.358 1.00 108.83 ? 436 TRP D CE3 1 
ATOM 3743 C CZ2 . TRP D 3 104 ? 190.418 243.972 136.464 1.00 108.83 ? 436 TRP D CZ2 1 
ATOM 3744 C CZ3 . TRP D 3 104 ? 188.558 242.460 136.194 1.00 108.83 ? 436 TRP D CZ3 1 
ATOM 3745 C CH2 . TRP D 3 104 ? 189.804 242.783 136.739 1.00 108.83 ? 436 TRP D CH2 1 
ATOM 3746 N N   . ASN D 3 105 ? 187.944 247.488 131.016 1.00 109.02 ? 437 ASN D N   1 
ATOM 3747 C CA  . ASN D 3 105 ? 188.975 248.319 130.411 1.00 109.02 ? 437 ASN D CA  1 
ATOM 3748 C C   . ASN D 3 105 ? 190.130 248.539 131.380 1.00 109.02 ? 437 ASN D C   1 
ATOM 3749 O O   . ASN D 3 105 ? 189.922 248.848 132.556 1.00 109.02 ? 437 ASN D O   1 
ATOM 3750 C CB  . ASN D 3 105 ? 188.378 249.661 129.989 1.00 109.02 ? 437 ASN D CB  1 
ATOM 3751 C CG  . ASN D 3 105 ? 189.122 250.292 128.833 1.00 109.02 ? 437 ASN D CG  1 
ATOM 3752 O OD1 . ASN D 3 105 ? 189.755 249.601 128.037 1.00 109.02 ? 437 ASN D OD1 1 
ATOM 3753 N ND2 . ASN D 3 105 ? 189.050 251.614 128.734 1.00 109.02 ? 437 ASN D ND2 1 
ATOM 3754 N N   . SER D 3 106 ? 191.356 248.383 130.875 1.00 113.96 ? 438 SER D N   1 
ATOM 3755 C CA  . SER D 3 106 ? 192.559 248.619 131.663 1.00 113.96 ? 438 SER D CA  1 
ATOM 3756 C C   . SER D 3 106 ? 193.555 249.517 130.939 1.00 113.96 ? 438 SER D C   1 
ATOM 3757 O O   . SER D 3 106 ? 194.666 249.719 131.441 1.00 113.96 ? 438 SER D O   1 
ATOM 3758 C CB  . SER D 3 106 ? 193.228 247.290 132.035 1.00 113.96 ? 438 SER D CB  1 
ATOM 3759 O OG  . SER D 3 106 ? 194.015 246.799 130.965 1.00 113.96 ? 438 SER D OG  1 
ATOM 3760 N N   . ASN D 3 107 ? 193.188 250.056 129.774 1.00 116.06 ? 439 ASN D N   1 
ATOM 3761 C CA  . ASN D 3 107 ? 194.097 250.922 129.032 1.00 116.06 ? 439 ASN D CA  1 
ATOM 3762 C C   . ASN D 3 107 ? 194.395 252.188 129.826 1.00 116.06 ? 439 ASN D C   1 
ATOM 3763 O O   . ASN D 3 107 ? 195.548 252.628 129.899 1.00 116.06 ? 439 ASN D O   1 
ATOM 3764 C CB  . ASN D 3 107 ? 193.478 251.242 127.663 1.00 116.06 ? 439 ASN D CB  1 
ATOM 3765 C CG  . ASN D 3 107 ? 194.265 252.275 126.847 1.00 116.06 ? 439 ASN D CG  1 
ATOM 3766 O OD1 . ASN D 3 107 ? 195.214 252.902 127.314 1.00 116.06 ? 439 ASN D OD1 1 
ATOM 3767 N ND2 . ASN D 3 107 ? 193.847 252.453 125.600 1.00 116.06 ? 439 ASN D ND2 1 
ATOM 3768 N N   . ASN D 3 108 ? 193.371 252.763 130.463 1.00 117.99 ? 440 ASN D N   1 
ATOM 3769 C CA  . ASN D 3 108 ? 193.530 254.056 131.123 1.00 117.99 ? 440 ASN D CA  1 
ATOM 3770 C C   . ASN D 3 108 ? 194.583 254.003 132.224 1.00 117.99 ? 440 ASN D C   1 
ATOM 3771 O O   . ASN D 3 108 ? 195.391 254.929 132.363 1.00 117.99 ? 440 ASN D O   1 
ATOM 3772 C CB  . ASN D 3 108 ? 192.189 254.520 131.690 1.00 117.99 ? 440 ASN D CB  1 
ATOM 3773 C CG  . ASN D 3 108 ? 192.137 256.018 131.910 1.00 117.99 ? 440 ASN D CG  1 
ATOM 3774 O OD1 . ASN D 3 108 ? 193.086 256.736 131.597 1.00 117.99 ? 440 ASN D OD1 1 
ATOM 3775 N ND2 . ASN D 3 108 ? 191.026 256.498 132.455 1.00 117.99 ? 440 ASN D ND2 1 
ATOM 3776 N N   . LEU D 3 109 ? 194.594 252.932 133.016 1.00 117.28 ? 441 LEU D N   1 
ATOM 3777 C CA  . LEU D 3 109 ? 195.519 252.810 134.135 1.00 117.28 ? 441 LEU D CA  1 
ATOM 3778 C C   . LEU D 3 109 ? 196.706 251.902 133.846 1.00 117.28 ? 441 LEU D C   1 
ATOM 3779 O O   . LEU D 3 109 ? 197.553 251.721 134.727 1.00 117.28 ? 441 LEU D O   1 
ATOM 3780 C CB  . LEU D 3 109 ? 194.783 252.308 135.383 1.00 117.28 ? 441 LEU D CB  1 
ATOM 3781 C CG  . LEU D 3 109 ? 194.043 253.339 136.244 1.00 117.28 ? 441 LEU D CG  1 
ATOM 3782 C CD1 . LEU D 3 109 ? 195.025 254.341 136.841 1.00 117.28 ? 441 LEU D CD1 1 
ATOM 3783 C CD2 . LEU D 3 109 ? 192.931 254.052 135.483 1.00 117.28 ? 441 LEU D CD2 1 
ATOM 3784 N N   . ASP D 3 110 ? 196.797 251.326 132.649 1.00 112.96 ? 442 ASP D N   1 
ATOM 3785 C CA  . ASP D 3 110 ? 197.935 250.488 132.281 1.00 112.96 ? 442 ASP D CA  1 
ATOM 3786 C C   . ASP D 3 110 ? 198.390 250.803 130.864 1.00 112.96 ? 442 ASP D C   1 
ATOM 3787 O O   . ASP D 3 110 ? 198.763 249.908 130.099 1.00 112.96 ? 442 ASP D O   1 
ATOM 3788 C CB  . ASP D 3 110 ? 197.601 249.004 132.425 1.00 112.96 ? 442 ASP D CB  1 
ATOM 3789 C CG  . ASP D 3 110 ? 197.361 248.598 133.866 1.00 112.96 ? 442 ASP D CG  1 
ATOM 3790 O OD1 . ASP D 3 110 ? 198.349 248.365 134.593 1.00 112.96 ? 442 ASP D OD1 1 
ATOM 3791 O OD2 . ASP D 3 110 ? 196.184 248.510 134.272 1.00 112.96 ? 442 ASP D OD2 1 
ATOM 3792 N N   . SER D 3 111 ? 198.367 252.086 130.495 1.00 115.07 ? 443 SER D N   1 
ATOM 3793 C CA  . SER D 3 111 ? 198.768 252.478 129.148 1.00 115.07 ? 443 SER D CA  1 
ATOM 3794 C C   . SER D 3 111 ? 200.270 252.317 128.949 1.00 115.07 ? 443 SER D C   1 
ATOM 3795 O O   . SER D 3 111 ? 200.722 251.863 127.891 1.00 115.07 ? 443 SER D O   1 
ATOM 3796 C CB  . SER D 3 111 ? 198.338 253.920 128.872 1.00 115.07 ? 443 SER D CB  1 
ATOM 3797 O OG  . SER D 3 111 ? 198.751 254.340 127.584 1.00 115.07 ? 443 SER D OG  1 
ATOM 3798 N N   . LYS D 3 112 ? 201.060 252.684 129.953 1.00 113.32 ? 444 LYS D N   1 
ATOM 3799 C CA  . LYS D 3 112 ? 202.512 252.596 129.855 1.00 113.32 ? 444 LYS D CA  1 
ATOM 3800 C C   . LYS D 3 112 ? 202.983 251.148 129.939 1.00 113.32 ? 444 LYS D C   1 
ATOM 3801 O O   . LYS D 3 112 ? 202.339 250.311 130.570 1.00 113.32 ? 444 LYS D O   1 
ATOM 3802 C CB  . LYS D 3 112 ? 203.174 253.429 130.953 1.00 113.32 ? 444 LYS D CB  1 
ATOM 3803 N N   . GLY D 3 115 ? 204.781 249.284 126.161 1.00 126.45 ? 447 GLY D N   1 
ATOM 3804 C CA  . GLY D 3 115 ? 205.048 247.940 125.685 1.00 126.45 ? 447 GLY D CA  1 
ATOM 3805 C C   . GLY D 3 115 ? 205.463 246.990 126.790 1.00 126.45 ? 447 GLY D C   1 
ATOM 3806 O O   . GLY D 3 115 ? 205.331 245.773 126.658 1.00 126.45 ? 447 GLY D O   1 
ATOM 3807 N N   . ASN D 3 116 ? 205.967 247.550 127.887 1.00 128.45 ? 448 ASN D N   1 
ATOM 3808 C CA  . ASN D 3 116 ? 206.418 246.746 129.014 1.00 128.45 ? 448 ASN D CA  1 
ATOM 3809 C C   . ASN D 3 116 ? 205.222 246.213 129.792 1.00 128.45 ? 448 ASN D C   1 
ATOM 3810 O O   . ASN D 3 116 ? 204.332 246.976 130.179 1.00 128.45 ? 448 ASN D O   1 
ATOM 3811 C CB  . ASN D 3 116 ? 207.321 247.572 129.930 1.00 128.45 ? 448 ASN D CB  1 
ATOM 3812 N N   . TYR D 3 117 ? 205.207 244.905 130.019 1.00 125.74 ? 449 TYR D N   1 
ATOM 3813 C CA  . TYR D 3 117 ? 204.131 244.247 130.749 1.00 125.74 ? 449 TYR D CA  1 
ATOM 3814 C C   . TYR D 3 117 ? 204.624 242.873 131.188 1.00 125.74 ? 449 TYR D C   1 
ATOM 3815 O O   . TYR D 3 117 ? 205.817 242.565 131.097 1.00 125.74 ? 449 TYR D O   1 
ATOM 3816 C CB  . TYR D 3 117 ? 202.864 244.156 129.892 1.00 125.74 ? 449 TYR D CB  1 
ATOM 3817 N N   . ASN D 3 118 ? 203.697 242.040 131.672 1.00 128.44 ? 450 ASN D N   1 
ATOM 3818 C CA  . ASN D 3 118 ? 204.038 240.684 132.084 1.00 128.44 ? 450 ASN D CA  1 
ATOM 3819 C C   . ASN D 3 118 ? 203.057 239.654 131.532 1.00 128.44 ? 450 ASN D C   1 
ATOM 3820 O O   . ASN D 3 118 ? 202.860 238.604 132.156 1.00 128.44 ? 450 ASN D O   1 
ATOM 3821 C CB  . ASN D 3 118 ? 204.096 240.576 133.612 1.00 128.44 ? 450 ASN D CB  1 
ATOM 3822 N N   . TYR D 3 119 ? 202.439 239.925 130.389 1.00 133.09 ? 451 TYR D N   1 
ATOM 3823 C CA  . TYR D 3 119 ? 201.480 239.020 129.776 1.00 133.09 ? 451 TYR D CA  1 
ATOM 3824 C C   . TYR D 3 119 ? 202.177 238.085 128.796 1.00 133.09 ? 451 TYR D C   1 
ATOM 3825 O O   . TYR D 3 119 ? 203.217 238.411 128.218 1.00 133.09 ? 451 TYR D O   1 
ATOM 3826 C CB  . TYR D 3 119 ? 200.380 239.804 129.057 1.00 133.09 ? 451 TYR D CB  1 
ATOM 3827 N N   . LEU D 3 120 ? 201.584 236.909 128.612 1.00 135.71 ? 452 LEU D N   1 
ATOM 3828 C CA  . LEU D 3 120 ? 202.096 235.912 127.681 1.00 135.71 ? 452 LEU D CA  1 
ATOM 3829 C C   . LEU D 3 120 ? 201.327 235.999 126.371 1.00 135.71 ? 452 LEU D C   1 
ATOM 3830 O O   . LEU D 3 120 ? 200.110 235.788 126.343 1.00 135.71 ? 452 LEU D O   1 
ATOM 3831 C CB  . LEU D 3 120 ? 201.986 234.502 128.263 1.00 135.71 ? 452 LEU D CB  1 
ATOM 3832 C CG  . LEU D 3 120 ? 202.754 234.214 129.554 1.00 135.71 ? 452 LEU D CG  1 
ATOM 3833 C CD1 . LEU D 3 120 ? 202.262 232.924 130.192 1.00 135.71 ? 452 LEU D CD1 1 
ATOM 3834 C CD2 . LEU D 3 120 ? 204.250 234.149 129.289 1.00 135.71 ? 452 LEU D CD2 1 
ATOM 3835 N N   . TYR D 3 121 ? 202.041 236.312 125.291 1.00 143.47 ? 453 TYR D N   1 
ATOM 3836 C CA  . TYR D 3 121 ? 201.471 236.365 123.954 1.00 143.47 ? 453 TYR D CA  1 
ATOM 3837 C C   . TYR D 3 121 ? 201.938 235.205 123.082 1.00 143.47 ? 453 TYR D C   1 
ATOM 3838 O O   . TYR D 3 121 ? 201.882 235.301 121.851 1.00 143.47 ? 453 TYR D O   1 
ATOM 3839 C CB  . TYR D 3 121 ? 201.806 237.702 123.289 1.00 143.47 ? 453 TYR D CB  1 
ATOM 3840 C CG  . TYR D 3 121 ? 203.285 238.018 123.235 1.00 143.47 ? 453 TYR D CG  1 
ATOM 3841 C CD1 . TYR D 3 121 ? 203.903 238.719 124.262 1.00 143.47 ? 453 TYR D CD1 1 
ATOM 3842 C CD2 . TYR D 3 121 ? 204.061 237.622 122.155 1.00 143.47 ? 453 TYR D CD2 1 
ATOM 3843 C CE1 . TYR D 3 121 ? 205.251 239.012 124.216 1.00 143.47 ? 453 TYR D CE1 1 
ATOM 3844 C CE2 . TYR D 3 121 ? 205.410 237.910 122.100 1.00 143.47 ? 453 TYR D CE2 1 
ATOM 3845 C CZ  . TYR D 3 121 ? 206.000 238.605 123.133 1.00 143.47 ? 453 TYR D CZ  1 
ATOM 3846 O OH  . TYR D 3 121 ? 207.344 238.895 123.082 1.00 143.47 ? 453 TYR D OH  1 
ATOM 3847 N N   . ARG D 3 122 ? 202.401 234.117 123.698 1.00 148.59 ? 454 ARG D N   1 
ATOM 3848 C CA  . ARG D 3 122 ? 202.932 232.973 122.967 1.00 148.59 ? 454 ARG D CA  1 
ATOM 3849 C C   . ARG D 3 122 ? 201.884 232.363 122.045 1.00 148.59 ? 454 ARG D C   1 
ATOM 3850 O O   . ARG D 3 122 ? 200.746 232.118 122.459 1.00 148.59 ? 454 ARG D O   1 
ATOM 3851 C CB  . ARG D 3 122 ? 203.455 231.915 123.942 1.00 148.59 ? 454 ARG D CB  1 
ATOM 3852 N N   . LEU D 3 123 ? 202.262 232.118 120.791 1.00 150.21 ? 455 LEU D N   1 
ATOM 3853 C CA  . LEU D 3 123 ? 201.389 231.493 119.806 1.00 150.21 ? 455 LEU D CA  1 
ATOM 3854 C C   . LEU D 3 123 ? 201.909 230.123 119.381 1.00 150.21 ? 455 LEU D C   1 
ATOM 3855 O O   . LEU D 3 123 ? 201.409 229.532 118.422 1.00 150.21 ? 455 LEU D O   1 
ATOM 3856 C CB  . LEU D 3 123 ? 201.220 232.403 118.591 1.00 150.21 ? 455 LEU D CB  1 
ATOM 3857 C CG  . LEU D 3 123 ? 200.561 233.758 118.858 1.00 150.21 ? 455 LEU D CG  1 
ATOM 3858 C CD1 . LEU D 3 123 ? 200.571 234.619 117.604 1.00 150.21 ? 455 LEU D CD1 1 
ATOM 3859 C CD2 . LEU D 3 123 ? 199.143 233.577 119.378 1.00 150.21 ? 455 LEU D CD2 1 
ATOM 3860 N N   . PHE D 3 124 ? 202.924 229.616 120.080 1.00 150.83 ? 456 PHE D N   1 
ATOM 3861 C CA  . PHE D 3 124 ? 203.491 228.309 119.773 1.00 150.83 ? 456 PHE D CA  1 
ATOM 3862 C C   . PHE D 3 124 ? 203.826 227.554 121.052 1.00 150.83 ? 456 PHE D C   1 
ATOM 3863 O O   . PHE D 3 124 ? 204.561 226.562 121.019 1.00 150.83 ? 456 PHE D O   1 
ATOM 3864 C CB  . PHE D 3 124 ? 204.738 228.457 118.898 1.00 150.83 ? 456 PHE D CB  1 
ATOM 3865 N N   . ARG D 3 125 ? 203.296 228.021 122.183 1.00 151.19 ? 457 ARG D N   1 
ATOM 3866 C CA  . ARG D 3 125 ? 203.585 227.411 123.476 1.00 151.19 ? 457 ARG D CA  1 
ATOM 3867 C C   . ARG D 3 125 ? 203.078 225.976 123.532 1.00 151.19 ? 457 ARG D C   1 
ATOM 3868 O O   . ARG D 3 125 ? 201.866 225.743 123.587 1.00 151.19 ? 457 ARG D O   1 
ATOM 3869 C CB  . ARG D 3 125 ? 202.966 228.236 124.606 1.00 151.19 ? 457 ARG D CB  1 
ATOM 3870 N N   . LYS D 3 126 ? 204.007 225.016 123.539 1.00 153.67 ? 458 LYS D N   1 
ATOM 3871 C CA  . LYS D 3 126 ? 203.689 223.592 123.552 1.00 153.67 ? 458 LYS D CA  1 
ATOM 3872 C C   . LYS D 3 126 ? 202.687 223.233 122.462 1.00 153.67 ? 458 LYS D C   1 
ATOM 3873 O O   . LYS D 3 126 ? 203.013 223.269 121.271 1.00 153.67 ? 458 LYS D O   1 
ATOM 3874 C CB  . LYS D 3 126 ? 203.152 223.176 124.924 1.00 153.67 ? 458 LYS D CB  1 
ATOM 3875 N N   . SER D 3 127 ? 201.465 222.886 122.863 1.00 152.76 ? 459 SER D N   1 
ATOM 3876 C CA  . SER D 3 127 ? 200.411 222.546 121.916 1.00 152.76 ? 459 SER D CA  1 
ATOM 3877 C C   . SER D 3 127 ? 199.049 222.914 122.490 1.00 152.76 ? 459 SER D C   1 
ATOM 3878 O O   . SER D 3 127 ? 198.966 223.654 123.476 1.00 152.76 ? 459 SER D O   1 
ATOM 3879 C CB  . SER D 3 127 ? 200.462 221.057 121.567 1.00 152.76 ? 459 SER D CB  1 
ATOM 3880 N N   . ASN D 3 128 ? 197.978 222.409 121.880 1.00 154.14 ? 460 ASN D N   1 
ATOM 3881 C CA  . ASN D 3 128 ? 196.634 222.655 122.385 1.00 154.14 ? 460 ASN D CA  1 
ATOM 3882 C C   . ASN D 3 128 ? 196.435 221.956 123.723 1.00 154.14 ? 460 ASN D C   1 
ATOM 3883 O O   . ASN D 3 128 ? 196.633 220.741 123.831 1.00 154.14 ? 460 ASN D O   1 
ATOM 3884 C CB  . ASN D 3 128 ? 195.585 222.186 121.375 1.00 154.14 ? 460 ASN D CB  1 
ATOM 3885 N N   . LEU D 3 129 ? 196.048 222.712 124.746 1.00 156.07 ? 461 LEU D N   1 
ATOM 3886 C CA  . LEU D 3 129 ? 195.869 222.153 126.075 1.00 156.07 ? 461 LEU D CA  1 
ATOM 3887 C C   . LEU D 3 129 ? 194.607 221.297 126.136 1.00 156.07 ? 461 LEU D C   1 
ATOM 3888 O O   . LEU D 3 129 ? 193.681 221.438 125.333 1.00 156.07 ? 461 LEU D O   1 
ATOM 3889 C CB  . LEU D 3 129 ? 195.807 223.266 127.121 1.00 156.07 ? 461 LEU D CB  1 
ATOM 3890 C CG  . LEU D 3 129 ? 197.074 224.104 127.295 1.00 156.07 ? 461 LEU D CG  1 
ATOM 3891 C CD1 . LEU D 3 129 ? 196.818 225.275 128.231 1.00 156.07 ? 461 LEU D CD1 1 
ATOM 3892 C CD2 . LEU D 3 129 ? 198.222 223.245 127.805 1.00 156.07 ? 461 LEU D CD2 1 
ATOM 3893 N N   . LYS D 3 130 ? 194.580 220.392 127.111 1.00 157.25 ? 462 LYS D N   1 
ATOM 3894 C CA  . LYS D 3 130 ? 193.432 219.517 127.354 1.00 157.25 ? 462 LYS D CA  1 
ATOM 3895 C C   . LYS D 3 130 ? 193.066 219.548 128.834 1.00 157.25 ? 462 LYS D C   1 
ATOM 3896 O O   . LYS D 3 130 ? 193.307 218.586 129.570 1.00 157.25 ? 462 LYS D O   1 
ATOM 3897 C CB  . LYS D 3 130 ? 193.730 218.093 126.890 1.00 157.25 ? 462 LYS D CB  1 
ATOM 3898 N N   . PRO D 3 131 ? 192.477 220.656 129.311 1.00 155.84 ? 463 PRO D N   1 
ATOM 3899 C CA  . PRO D 3 131 ? 192.105 220.786 130.724 1.00 155.84 ? 463 PRO D CA  1 
ATOM 3900 C C   . PRO D 3 131 ? 190.968 219.849 131.122 1.00 155.84 ? 463 PRO D C   1 
ATOM 3901 O O   . PRO D 3 131 ? 189.810 220.268 131.129 1.00 155.84 ? 463 PRO D O   1 
ATOM 3902 C CB  . PRO D 3 131 ? 191.671 222.250 130.838 1.00 155.84 ? 463 PRO D CB  1 
ATOM 3903 C CG  . PRO D 3 131 ? 191.212 222.610 129.469 1.00 155.84 ? 463 PRO D CG  1 
ATOM 3904 C CD  . PRO D 3 131 ? 192.099 221.847 128.529 1.00 155.84 ? 463 PRO D CD  1 
ATOM 3905 N N   . GLN D 3 166 ? 192.261 258.357 119.778 1.00 162.02 ? 498 GLN D N   1 
ATOM 3906 C CA  . GLN D 3 166 ? 193.715 258.249 119.806 1.00 162.02 ? 498 GLN D CA  1 
ATOM 3907 C C   . GLN D 3 166 ? 194.226 257.437 118.621 1.00 162.02 ? 498 GLN D C   1 
ATOM 3908 O O   . GLN D 3 166 ? 194.329 256.213 118.703 1.00 162.02 ? 498 GLN D O   1 
ATOM 3909 C CB  . GLN D 3 166 ? 194.181 257.616 121.119 1.00 162.02 ? 498 GLN D CB  1 
ATOM 3910 N N   . PRO D 3 167 ? 194.534 258.121 117.516 1.00 161.25 ? 499 PRO D N   1 
ATOM 3911 C CA  . PRO D 3 167 ? 195.058 257.407 116.339 1.00 161.25 ? 499 PRO D CA  1 
ATOM 3912 C C   . PRO D 3 167 ? 196.356 256.667 116.607 1.00 161.25 ? 499 PRO D C   1 
ATOM 3913 O O   . PRO D 3 167 ? 196.590 255.611 116.006 1.00 161.25 ? 499 PRO D O   1 
ATOM 3914 C CB  . PRO D 3 167 ? 195.250 258.527 115.305 1.00 161.25 ? 499 PRO D CB  1 
ATOM 3915 C CG  . PRO D 3 167 ? 194.382 259.649 115.772 1.00 161.25 ? 499 PRO D CG  1 
ATOM 3916 C CD  . PRO D 3 167 ? 194.348 259.559 117.265 1.00 161.25 ? 499 PRO D CD  1 
ATOM 3917 N N   . THR D 3 168 ? 197.212 257.194 117.486 1.00 158.35 ? 500 THR D N   1 
ATOM 3918 C CA  . THR D 3 168 ? 198.481 256.530 117.773 1.00 158.35 ? 500 THR D CA  1 
ATOM 3919 C C   . THR D 3 168 ? 198.262 255.174 118.434 1.00 158.35 ? 500 THR D C   1 
ATOM 3920 O O   . THR D 3 168 ? 198.926 254.191 118.084 1.00 158.35 ? 500 THR D O   1 
ATOM 3921 C CB  . THR D 3 168 ? 199.352 257.421 118.659 1.00 158.35 ? 500 THR D CB  1 
ATOM 3922 N N   . ASN D 3 169 ? 197.341 255.102 119.391 1.00 151.09 ? 501 ASN D N   1 
ATOM 3923 C CA  . ASN D 3 169 ? 197.062 253.841 120.062 1.00 151.09 ? 501 ASN D CA  1 
ATOM 3924 C C   . ASN D 3 169 ? 196.381 252.866 119.109 1.00 151.09 ? 501 ASN D C   1 
ATOM 3925 O O   . ASN D 3 169 ? 195.504 253.238 118.323 1.00 151.09 ? 501 ASN D O   1 
ATOM 3926 C CB  . ASN D 3 169 ? 196.184 254.074 121.293 1.00 151.09 ? 501 ASN D CB  1 
ATOM 3927 C CG  . ASN D 3 169 ? 196.899 254.854 122.380 1.00 151.09 ? 501 ASN D CG  1 
ATOM 3928 O OD1 . ASN D 3 169 ? 197.830 255.611 122.108 1.00 151.09 ? 501 ASN D OD1 1 
ATOM 3929 N ND2 . ASN D 3 169 ? 196.464 254.672 123.622 1.00 151.09 ? 501 ASN D ND2 1 
ATOM 3930 N N   . GLY D 3 170 ? 196.795 251.603 119.181 1.00 138.72 ? 502 GLY D N   1 
ATOM 3931 C CA  . GLY D 3 170 ? 196.193 250.586 118.349 1.00 138.72 ? 502 GLY D CA  1 
ATOM 3932 C C   . GLY D 3 170 ? 194.768 250.274 118.761 1.00 138.72 ? 502 GLY D C   1 
ATOM 3933 O O   . GLY D 3 170 ? 194.414 250.260 119.941 1.00 138.72 ? 502 GLY D O   1 
ATOM 3934 N N   . VAL D 3 171 ? 193.930 250.019 117.755 1.00 132.72 ? 503 VAL D N   1 
ATOM 3935 C CA  . VAL D 3 171 ? 192.525 249.730 118.022 1.00 132.72 ? 503 VAL D CA  1 
ATOM 3936 C C   . VAL D 3 171 ? 192.372 248.367 118.686 1.00 132.72 ? 503 VAL D C   1 
ATOM 3937 O O   . VAL D 3 171 ? 191.625 248.216 119.661 1.00 132.72 ? 503 VAL D O   1 
ATOM 3938 C CB  . VAL D 3 171 ? 191.702 249.835 116.725 1.00 132.72 ? 503 VAL D CB  1 
ATOM 3939 C CG1 . VAL D 3 171 ? 191.503 251.292 116.345 1.00 132.72 ? 503 VAL D CG1 1 
ATOM 3940 C CG2 . VAL D 3 171 ? 192.389 249.088 115.590 1.00 132.72 ? 503 VAL D CG2 1 
ATOM 3941 N N   . GLY D 3 172 ? 193.072 247.357 118.178 1.00 128.73 ? 504 GLY D N   1 
ATOM 3942 C CA  . GLY D 3 172 ? 193.032 246.025 118.738 1.00 128.73 ? 504 GLY D CA  1 
ATOM 3943 C C   . GLY D 3 172 ? 194.089 245.725 119.772 1.00 128.73 ? 504 GLY D C   1 
ATOM 3944 O O   . GLY D 3 172 ? 194.176 244.588 120.243 1.00 128.73 ? 504 GLY D O   1 
ATOM 3945 N N   . TYR D 3 173 ? 194.904 246.711 120.141 1.00 127.67 ? 505 TYR D N   1 
ATOM 3946 C CA  . TYR D 3 173 ? 195.964 246.523 121.121 1.00 127.67 ? 505 TYR D CA  1 
ATOM 3947 C C   . TYR D 3 173 ? 195.628 247.114 122.483 1.00 127.67 ? 505 TYR D C   1 
ATOM 3948 O O   . TYR D 3 173 ? 196.479 247.088 123.379 1.00 127.67 ? 505 TYR D O   1 
ATOM 3949 C CB  . TYR D 3 173 ? 197.273 247.131 120.603 1.00 127.67 ? 505 TYR D CB  1 
ATOM 3950 N N   . GLN D 3 174 ? 194.425 247.647 122.662 1.00 126.43 ? 506 GLN D N   1 
ATOM 3951 C CA  . GLN D 3 174 ? 194.055 248.209 123.952 1.00 126.43 ? 506 GLN D CA  1 
ATOM 3952 C C   . GLN D 3 174 ? 193.950 247.095 124.988 1.00 126.43 ? 506 GLN D C   1 
ATOM 3953 O O   . GLN D 3 174 ? 193.256 246.098 124.761 1.00 126.43 ? 506 GLN D O   1 
ATOM 3954 C CB  . GLN D 3 174 ? 192.728 248.962 123.849 1.00 126.43 ? 506 GLN D CB  1 
ATOM 3955 C CG  . GLN D 3 174 ? 192.622 249.858 122.630 1.00 126.43 ? 506 GLN D CG  1 
ATOM 3956 C CD  . GLN D 3 174 ? 193.378 251.159 122.798 1.00 126.43 ? 506 GLN D CD  1 
ATOM 3957 O OE1 . GLN D 3 174 ? 192.819 252.163 123.238 1.00 126.43 ? 506 GLN D OE1 1 
ATOM 3958 N NE2 . GLN D 3 174 ? 194.658 251.149 122.446 1.00 126.43 ? 506 GLN D NE2 1 
ATOM 3959 N N   . PRO D 3 175 ? 194.621 247.225 126.136 1.00 119.69 ? 507 PRO D N   1 
ATOM 3960 C CA  . PRO D 3 175 ? 194.642 246.135 127.122 1.00 119.69 ? 507 PRO D CA  1 
ATOM 3961 C C   . PRO D 3 175 ? 193.327 246.054 127.885 1.00 119.69 ? 507 PRO D C   1 
ATOM 3962 O O   . PRO D 3 175 ? 192.852 247.047 128.440 1.00 119.69 ? 507 PRO D O   1 
ATOM 3963 C CB  . PRO D 3 175 ? 195.806 246.515 128.044 1.00 119.69 ? 507 PRO D CB  1 
ATOM 3964 C CG  . PRO D 3 175 ? 195.913 247.991 127.928 1.00 119.69 ? 507 PRO D CG  1 
ATOM 3965 C CD  . PRO D 3 175 ? 195.446 248.372 126.550 1.00 119.69 ? 507 PRO D CD  1 
ATOM 3966 N N   . TYR D 3 176 ? 192.741 244.861 127.907 1.00 111.97 ? 508 TYR D N   1 
ATOM 3967 C CA  . TYR D 3 176 ? 191.529 244.575 128.662 1.00 111.97 ? 508 TYR D CA  1 
ATOM 3968 C C   . TYR D 3 176 ? 191.847 243.522 129.715 1.00 111.97 ? 508 TYR D C   1 
ATOM 3969 O O   . TYR D 3 176 ? 192.386 242.458 129.391 1.00 111.97 ? 508 TYR D O   1 
ATOM 3970 C CB  . TYR D 3 176 ? 190.411 244.081 127.741 1.00 111.97 ? 508 TYR D CB  1 
ATOM 3971 C CG  . TYR D 3 176 ? 189.534 245.177 127.178 1.00 111.97 ? 508 TYR D CG  1 
ATOM 3972 C CD1 . TYR D 3 176 ? 189.963 245.957 126.113 1.00 111.97 ? 508 TYR D CD1 1 
ATOM 3973 C CD2 . TYR D 3 176 ? 188.275 245.424 127.705 1.00 111.97 ? 508 TYR D CD2 1 
ATOM 3974 C CE1 . TYR D 3 176 ? 189.165 246.957 125.595 1.00 111.97 ? 508 TYR D CE1 1 
ATOM 3975 C CE2 . TYR D 3 176 ? 187.470 246.422 127.192 1.00 111.97 ? 508 TYR D CE2 1 
ATOM 3976 C CZ  . TYR D 3 176 ? 187.920 247.185 126.138 1.00 111.97 ? 508 TYR D CZ  1 
ATOM 3977 O OH  . TYR D 3 176 ? 187.121 248.181 125.624 1.00 111.97 ? 508 TYR D OH  1 
ATOM 3978 N N   . ARG D 3 177 ? 191.517 243.817 130.968 1.00 110.56 ? 509 ARG D N   1 
ATOM 3979 C CA  . ARG D 3 177 ? 191.781 242.894 132.063 1.00 110.56 ? 509 ARG D CA  1 
ATOM 3980 C C   . ARG D 3 177 ? 190.586 241.961 132.213 1.00 110.56 ? 509 ARG D C   1 
ATOM 3981 O O   . ARG D 3 177 ? 189.454 242.419 132.412 1.00 110.56 ? 509 ARG D O   1 
ATOM 3982 C CB  . ARG D 3 177 ? 192.065 243.651 133.359 1.00 110.56 ? 509 ARG D CB  1 
ATOM 3983 C CG  . ARG D 3 177 ? 193.551 243.804 133.663 1.00 110.56 ? 509 ARG D CG  1 
ATOM 3984 C CD  . ARG D 3 177 ? 193.778 244.385 135.047 1.00 110.56 ? 509 ARG D CD  1 
ATOM 3985 N NE  . ARG D 3 177 ? 195.117 244.108 135.553 1.00 110.56 ? 509 ARG D NE  1 
ATOM 3986 C CZ  . ARG D 3 177 ? 195.966 245.035 135.975 1.00 110.56 ? 509 ARG D CZ  1 
ATOM 3987 N NH1 . ARG D 3 177 ? 195.659 246.321 135.936 1.00 110.56 ? 509 ARG D NH1 1 
ATOM 3988 N NH2 . ARG D 3 177 ? 197.151 244.663 136.449 1.00 110.56 ? 509 ARG D NH2 1 
ATOM 3989 N N   . VAL D 3 178 ? 190.841 240.660 132.108 1.00 110.57 ? 510 VAL D N   1 
ATOM 3990 C CA  . VAL D 3 178 ? 189.803 239.639 132.044 1.00 110.57 ? 510 VAL D CA  1 
ATOM 3991 C C   . VAL D 3 178 ? 189.931 238.734 133.261 1.00 110.57 ? 510 VAL D C   1 
ATOM 3992 O O   . VAL D 3 178 ? 191.008 238.182 133.526 1.00 110.57 ? 510 VAL D O   1 
ATOM 3993 C CB  . VAL D 3 178 ? 189.906 238.824 130.743 1.00 110.57 ? 510 VAL D CB  1 
ATOM 3994 C CG1 . VAL D 3 178 ? 188.738 237.866 130.619 1.00 110.57 ? 510 VAL D CG1 1 
ATOM 3995 C CG2 . VAL D 3 178 ? 189.976 239.751 129.541 1.00 110.57 ? 510 VAL D CG2 1 
ATOM 3996 N N   . VAL D 3 179 ? 188.832 238.579 133.994 1.00 106.50 ? 511 VAL D N   1 
ATOM 3997 C CA  . VAL D 3 179 ? 188.742 237.652 135.114 1.00 106.50 ? 511 VAL D CA  1 
ATOM 3998 C C   . VAL D 3 179 ? 187.612 236.679 134.826 1.00 106.50 ? 511 VAL D C   1 
ATOM 3999 O O   . VAL D 3 179 ? 186.469 237.095 134.601 1.00 106.50 ? 511 VAL D O   1 
ATOM 4000 C CB  . VAL D 3 179 ? 188.509 238.382 136.444 1.00 106.50 ? 511 VAL D CB  1 
ATOM 4001 C CG1 . VAL D 3 179 ? 188.301 237.378 137.562 1.00 106.50 ? 511 VAL D CG1 1 
ATOM 4002 C CG2 . VAL D 3 179 ? 189.692 239.270 136.755 1.00 106.50 ? 511 VAL D CG2 1 
ATOM 4003 N N   . VAL D 3 180 ? 187.925 235.388 134.841 1.00 106.12 ? 512 VAL D N   1 
ATOM 4004 C CA  . VAL D 3 180 ? 186.951 234.337 134.578 1.00 106.12 ? 512 VAL D CA  1 
ATOM 4005 C C   . VAL D 3 180 ? 186.750 233.533 135.855 1.00 106.12 ? 512 VAL D C   1 
ATOM 4006 O O   . VAL D 3 180 ? 187.718 233.072 136.470 1.00 106.12 ? 512 VAL D O   1 
ATOM 4007 C CB  . VAL D 3 180 ? 187.388 233.440 133.404 1.00 106.12 ? 512 VAL D CB  1 
ATOM 4008 C CG1 . VAL D 3 180 ? 188.769 232.856 133.651 1.00 106.12 ? 512 VAL D CG1 1 
ATOM 4009 C CG2 . VAL D 3 180 ? 186.372 232.335 133.178 1.00 106.12 ? 512 VAL D CG2 1 
ATOM 4010 N N   . LEU D 3 181 ? 185.494 233.389 136.264 1.00 103.55 ? 513 LEU D N   1 
ATOM 4011 C CA  . LEU D 3 181 ? 185.133 232.682 137.482 1.00 103.55 ? 513 LEU D CA  1 
ATOM 4012 C C   . LEU D 3 181 ? 184.503 231.348 137.116 1.00 103.55 ? 513 LEU D C   1 
ATOM 4013 O O   . LEU D 3 181 ? 183.487 231.309 136.416 1.00 103.55 ? 513 LEU D O   1 
ATOM 4014 C CB  . LEU D 3 181 ? 184.161 233.508 138.328 1.00 103.55 ? 513 LEU D CB  1 
ATOM 4015 C CG  . LEU D 3 181 ? 184.738 234.675 139.129 1.00 103.55 ? 513 LEU D CG  1 
ATOM 4016 C CD1 . LEU D 3 181 ? 184.786 235.938 138.288 1.00 103.55 ? 513 LEU D CD1 1 
ATOM 4017 C CD2 . LEU D 3 181 ? 183.918 234.899 140.386 1.00 103.55 ? 513 LEU D CD2 1 
ATOM 4018 N N   . SER D 3 182 ? 185.105 230.265 137.590 1.00 108.65 ? 514 SER D N   1 
ATOM 4019 C CA  . SER D 3 182 ? 184.610 228.910 137.368 1.00 108.65 ? 514 SER D CA  1 
ATOM 4020 C C   . SER D 3 182 ? 184.090 228.384 138.702 1.00 108.65 ? 514 SER D C   1 
ATOM 4021 O O   . SER D 3 182 ? 184.844 228.272 139.672 1.00 108.65 ? 514 SER D O   1 
ATOM 4022 C CB  . SER D 3 182 ? 185.705 228.012 136.801 1.00 108.65 ? 514 SER D CB  1 
ATOM 4023 O OG  . SER D 3 182 ? 186.334 228.613 135.684 1.00 108.65 ? 514 SER D OG  1 
ATOM 4024 N N   . PHE D 3 183 ? 182.797 228.073 138.747 1.00 108.88 ? 515 PHE D N   1 
ATOM 4025 C CA  . PHE D 3 183 ? 182.185 227.541 139.955 1.00 108.88 ? 515 PHE D CA  1 
ATOM 4026 C C   . PHE D 3 183 ? 182.187 226.019 139.911 1.00 108.88 ? 515 PHE D C   1 
ATOM 4027 O O   . PHE D 3 183 ? 181.749 225.417 138.926 1.00 108.88 ? 515 PHE D O   1 
ATOM 4028 C CB  . PHE D 3 183 ? 180.756 228.063 140.112 1.00 108.88 ? 515 PHE D CB  1 
ATOM 4029 C CG  . PHE D 3 183 ? 180.619 229.543 139.883 1.00 108.88 ? 515 PHE D CG  1 
ATOM 4030 C CD1 . PHE D 3 183 ? 180.708 230.430 140.942 1.00 108.88 ? 515 PHE D CD1 1 
ATOM 4031 C CD2 . PHE D 3 183 ? 180.381 230.045 138.615 1.00 108.88 ? 515 PHE D CD2 1 
ATOM 4032 C CE1 . PHE D 3 183 ? 180.578 231.790 140.738 1.00 108.88 ? 515 PHE D CE1 1 
ATOM 4033 C CE2 . PHE D 3 183 ? 180.249 231.403 138.404 1.00 108.88 ? 515 PHE D CE2 1 
ATOM 4034 C CZ  . PHE D 3 183 ? 180.348 232.276 139.467 1.00 108.88 ? 515 PHE D CZ  1 
ATOM 4035 N N   . GLU D 3 184 ? 182.690 225.398 140.981 1.00 117.80 ? 516 GLU D N   1 
ATOM 4036 C CA  . GLU D 3 184 ? 182.721 223.940 141.042 1.00 117.80 ? 516 GLU D CA  1 
ATOM 4037 C C   . GLU D 3 184 ? 181.313 223.356 141.065 1.00 117.80 ? 516 GLU D C   1 
ATOM 4038 O O   . GLU D 3 184 ? 181.043 222.348 140.402 1.00 117.80 ? 516 GLU D O   1 
ATOM 4039 C CB  . GLU D 3 184 ? 183.512 223.483 142.268 1.00 117.80 ? 516 GLU D CB  1 
ATOM 4040 N N   . LEU D 3 185 ? 180.407 223.973 141.815 1.00 118.19 ? 517 LEU D N   1 
ATOM 4041 C CA  . LEU D 3 185 ? 179.033 223.495 141.905 1.00 118.19 ? 517 LEU D CA  1 
ATOM 4042 C C   . LEU D 3 185 ? 178.043 224.616 141.609 1.00 118.19 ? 517 LEU D C   1 
ATOM 4043 O O   . LEU D 3 185 ? 178.100 225.244 140.552 1.00 118.19 ? 517 LEU D O   1 
ATOM 4044 C CB  . LEU D 3 185 ? 178.760 222.904 143.289 1.00 118.19 ? 517 LEU D CB  1 
# 
