data_9J52
# 
_entry.id   9J52 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9J52         pdb_00009j52 10.2210/pdb9j52/pdb 
WWPDB D_1300050350 ?            ?                   
EMDB  EMD-61140    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9J52 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'CryoEM structure of human XPR1 in complex with phosphate in state B' 
_pdbx_database_related.db_id          EMD-61140 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              liuzhu@mail.hzau.edu.cn 
_pdbx_contact_author.name_first         Zhu 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4073-7237 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, W.H.' 1 ? 
'Chen, Y.K.'  2 ? 
'Guan, Z.Y.'  3 ? 
'Liu, Z.'     4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                18 
_citation.page_last                 18 
_citation.title                     'Structural insights into the mechanism of phosphate recognition and transport by XPR1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55471-9 
_citation.pdbx_database_id_PubMed   39747008 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, W.' 1  ?                   
primary 'Chen, Y.'  2  0000-0002-0344-880X 
primary 'Guan, Z.'  3  0009-0000-5527-543X 
primary 'Wang, Y.'  4  0000-0001-9156-0377 
primary 'Tang, M.'  5  ?                   
primary 'Du, Z.'    6  ?                   
primary 'Zhang, J.' 7  ?                   
primary 'Cheng, M.' 8  ?                   
primary 'Zuo, J.'   9  ?                   
primary 'Liu, Y.'   10 ?                   
primary 'Wang, Q.'  11 0000-0002-7048-638X 
primary 'Liu, Y.'   12 ?                   
primary 'Zhang, D.' 13 0000-0002-5299-0718 
primary 'Yin, P.'   14 0000-0001-8001-221X 
primary 'Ma, L.'    15 0000-0001-7694-7514 
primary 'Liu, Z.'   16 0000-0003-4073-7237 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Solute carrier family 53 member 1'    84595.844 2 ? ? ? ? 
2 non-polymer syn 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE 790.145   4 ? ? ? ? 
3 non-polymer syn 'PHOSPHATE ION'                        94.971    1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Phosphate exporter SLC53A1,Protein SYG1 homolog,Xenotropic and polytropic murine leukemia virus receptor X3,X-receptor,Xenotropic and polytropic retrovirus receptor 1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTLEDYKDHDGDYKDHDIDYKDDDDK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTLEDYKDHDGDYKDHDIDYKDDDDK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE PC1 
3 'PHOSPHATE ION'                        PO4 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   ALA n 
1 5   GLU n 
1 6   HIS n 
1 7   LEU n 
1 8   SER n 
1 9   ALA n 
1 10  HIS n 
1 11  ILE n 
1 12  THR n 
1 13  PRO n 
1 14  GLU n 
1 15  TRP n 
1 16  ARG n 
1 17  LYS n 
1 18  GLN n 
1 19  TYR n 
1 20  ILE n 
1 21  GLN n 
1 22  TYR n 
1 23  GLU n 
1 24  ALA n 
1 25  PHE n 
1 26  LYS n 
1 27  ASP n 
1 28  MET n 
1 29  LEU n 
1 30  TYR n 
1 31  SER n 
1 32  ALA n 
1 33  GLN n 
1 34  ASP n 
1 35  GLN n 
1 36  ALA n 
1 37  PRO n 
1 38  SER n 
1 39  VAL n 
1 40  GLU n 
1 41  VAL n 
1 42  THR n 
1 43  ASP n 
1 44  GLU n 
1 45  ASP n 
1 46  THR n 
1 47  VAL n 
1 48  LYS n 
1 49  ARG n 
1 50  TYR n 
1 51  PHE n 
1 52  ALA n 
1 53  LYS n 
1 54  PHE n 
1 55  GLU n 
1 56  GLU n 
1 57  LYS n 
1 58  PHE n 
1 59  PHE n 
1 60  GLN n 
1 61  THR n 
1 62  CYS n 
1 63  GLU n 
1 64  LYS n 
1 65  GLU n 
1 66  LEU n 
1 67  ALA n 
1 68  LYS n 
1 69  ILE n 
1 70  ASN n 
1 71  THR n 
1 72  PHE n 
1 73  TYR n 
1 74  SER n 
1 75  GLU n 
1 76  LYS n 
1 77  LEU n 
1 78  ALA n 
1 79  GLU n 
1 80  ALA n 
1 81  GLN n 
1 82  ARG n 
1 83  ARG n 
1 84  PHE n 
1 85  ALA n 
1 86  THR n 
1 87  LEU n 
1 88  GLN n 
1 89  ASN n 
1 90  GLU n 
1 91  LEU n 
1 92  GLN n 
1 93  SER n 
1 94  SER n 
1 95  LEU n 
1 96  ASP n 
1 97  ALA n 
1 98  GLN n 
1 99  LYS n 
1 100 GLU n 
1 101 SER n 
1 102 THR n 
1 103 GLY n 
1 104 VAL n 
1 105 THR n 
1 106 THR n 
1 107 LEU n 
1 108 ARG n 
1 109 GLN n 
1 110 ARG n 
1 111 ARG n 
1 112 LYS n 
1 113 PRO n 
1 114 VAL n 
1 115 PHE n 
1 116 HIS n 
1 117 LEU n 
1 118 SER n 
1 119 HIS n 
1 120 GLU n 
1 121 GLU n 
1 122 ARG n 
1 123 VAL n 
1 124 GLN n 
1 125 HIS n 
1 126 ARG n 
1 127 ASN n 
1 128 ILE n 
1 129 LYS n 
1 130 ASP n 
1 131 LEU n 
1 132 LYS n 
1 133 LEU n 
1 134 ALA n 
1 135 PHE n 
1 136 SER n 
1 137 GLU n 
1 138 PHE n 
1 139 TYR n 
1 140 LEU n 
1 141 SER n 
1 142 LEU n 
1 143 ILE n 
1 144 LEU n 
1 145 LEU n 
1 146 GLN n 
1 147 ASN n 
1 148 TYR n 
1 149 GLN n 
1 150 ASN n 
1 151 LEU n 
1 152 ASN n 
1 153 PHE n 
1 154 THR n 
1 155 GLY n 
1 156 PHE n 
1 157 ARG n 
1 158 LYS n 
1 159 ILE n 
1 160 LEU n 
1 161 LYS n 
1 162 LYS n 
1 163 HIS n 
1 164 ASP n 
1 165 LYS n 
1 166 ILE n 
1 167 LEU n 
1 168 GLU n 
1 169 THR n 
1 170 SER n 
1 171 ARG n 
1 172 GLY n 
1 173 ALA n 
1 174 ASP n 
1 175 TRP n 
1 176 ARG n 
1 177 VAL n 
1 178 ALA n 
1 179 HIS n 
1 180 VAL n 
1 181 GLU n 
1 182 VAL n 
1 183 ALA n 
1 184 PRO n 
1 185 PHE n 
1 186 TYR n 
1 187 THR n 
1 188 CYS n 
1 189 LYS n 
1 190 LYS n 
1 191 ILE n 
1 192 ASN n 
1 193 GLN n 
1 194 LEU n 
1 195 ILE n 
1 196 SER n 
1 197 GLU n 
1 198 THR n 
1 199 GLU n 
1 200 ALA n 
1 201 VAL n 
1 202 VAL n 
1 203 THR n 
1 204 ASN n 
1 205 GLU n 
1 206 LEU n 
1 207 GLU n 
1 208 ASP n 
1 209 GLY n 
1 210 ASP n 
1 211 ARG n 
1 212 GLN n 
1 213 LYS n 
1 214 ALA n 
1 215 MET n 
1 216 LYS n 
1 217 ARG n 
1 218 LEU n 
1 219 ARG n 
1 220 VAL n 
1 221 PRO n 
1 222 PRO n 
1 223 LEU n 
1 224 GLY n 
1 225 ALA n 
1 226 ALA n 
1 227 GLN n 
1 228 PRO n 
1 229 ALA n 
1 230 PRO n 
1 231 ALA n 
1 232 TRP n 
1 233 THR n 
1 234 THR n 
1 235 PHE n 
1 236 ARG n 
1 237 VAL n 
1 238 GLY n 
1 239 LEU n 
1 240 PHE n 
1 241 CYS n 
1 242 GLY n 
1 243 ILE n 
1 244 PHE n 
1 245 ILE n 
1 246 VAL n 
1 247 LEU n 
1 248 ASN n 
1 249 ILE n 
1 250 THR n 
1 251 LEU n 
1 252 VAL n 
1 253 LEU n 
1 254 ALA n 
1 255 ALA n 
1 256 VAL n 
1 257 PHE n 
1 258 LYS n 
1 259 LEU n 
1 260 GLU n 
1 261 THR n 
1 262 ASP n 
1 263 ARG n 
1 264 SER n 
1 265 ILE n 
1 266 TRP n 
1 267 PRO n 
1 268 LEU n 
1 269 ILE n 
1 270 ARG n 
1 271 ILE n 
1 272 TYR n 
1 273 ARG n 
1 274 GLY n 
1 275 GLY n 
1 276 PHE n 
1 277 LEU n 
1 278 LEU n 
1 279 ILE n 
1 280 GLU n 
1 281 PHE n 
1 282 LEU n 
1 283 PHE n 
1 284 LEU n 
1 285 LEU n 
1 286 GLY n 
1 287 ILE n 
1 288 ASN n 
1 289 THR n 
1 290 TYR n 
1 291 GLY n 
1 292 TRP n 
1 293 ARG n 
1 294 GLN n 
1 295 ALA n 
1 296 GLY n 
1 297 VAL n 
1 298 ASN n 
1 299 HIS n 
1 300 VAL n 
1 301 LEU n 
1 302 ILE n 
1 303 PHE n 
1 304 GLU n 
1 305 LEU n 
1 306 ASN n 
1 307 PRO n 
1 308 ARG n 
1 309 SER n 
1 310 ASN n 
1 311 LEU n 
1 312 SER n 
1 313 HIS n 
1 314 GLN n 
1 315 HIS n 
1 316 LEU n 
1 317 PHE n 
1 318 GLU n 
1 319 ILE n 
1 320 ALA n 
1 321 GLY n 
1 322 PHE n 
1 323 LEU n 
1 324 GLY n 
1 325 ILE n 
1 326 LEU n 
1 327 TRP n 
1 328 CYS n 
1 329 LEU n 
1 330 SER n 
1 331 LEU n 
1 332 LEU n 
1 333 ALA n 
1 334 CYS n 
1 335 PHE n 
1 336 PHE n 
1 337 ALA n 
1 338 PRO n 
1 339 ILE n 
1 340 SER n 
1 341 VAL n 
1 342 ILE n 
1 343 PRO n 
1 344 THR n 
1 345 TYR n 
1 346 VAL n 
1 347 TYR n 
1 348 PRO n 
1 349 LEU n 
1 350 ALA n 
1 351 LEU n 
1 352 TYR n 
1 353 GLY n 
1 354 PHE n 
1 355 MET n 
1 356 VAL n 
1 357 PHE n 
1 358 PHE n 
1 359 LEU n 
1 360 ILE n 
1 361 ASN n 
1 362 PRO n 
1 363 THR n 
1 364 LYS n 
1 365 THR n 
1 366 PHE n 
1 367 TYR n 
1 368 TYR n 
1 369 LYS n 
1 370 SER n 
1 371 ARG n 
1 372 PHE n 
1 373 TRP n 
1 374 LEU n 
1 375 LEU n 
1 376 LYS n 
1 377 LEU n 
1 378 LEU n 
1 379 PHE n 
1 380 ARG n 
1 381 VAL n 
1 382 PHE n 
1 383 THR n 
1 384 ALA n 
1 385 PRO n 
1 386 PHE n 
1 387 HIS n 
1 388 LYS n 
1 389 VAL n 
1 390 GLY n 
1 391 PHE n 
1 392 ALA n 
1 393 ASP n 
1 394 PHE n 
1 395 TRP n 
1 396 LEU n 
1 397 ALA n 
1 398 ASP n 
1 399 GLN n 
1 400 LEU n 
1 401 ASN n 
1 402 SER n 
1 403 LEU n 
1 404 SER n 
1 405 VAL n 
1 406 ILE n 
1 407 LEU n 
1 408 MET n 
1 409 ASP n 
1 410 LEU n 
1 411 GLU n 
1 412 TYR n 
1 413 MET n 
1 414 ILE n 
1 415 CYS n 
1 416 PHE n 
1 417 TYR n 
1 418 SER n 
1 419 LEU n 
1 420 GLU n 
1 421 LEU n 
1 422 LYS n 
1 423 TRP n 
1 424 ASP n 
1 425 GLU n 
1 426 SER n 
1 427 LYS n 
1 428 GLY n 
1 429 LEU n 
1 430 LEU n 
1 431 PRO n 
1 432 ASN n 
1 433 ASN n 
1 434 SER n 
1 435 GLU n 
1 436 GLU n 
1 437 SER n 
1 438 GLY n 
1 439 ILE n 
1 440 CYS n 
1 441 HIS n 
1 442 LYS n 
1 443 TYR n 
1 444 THR n 
1 445 TYR n 
1 446 GLY n 
1 447 VAL n 
1 448 ARG n 
1 449 ALA n 
1 450 ILE n 
1 451 VAL n 
1 452 GLN n 
1 453 CYS n 
1 454 ILE n 
1 455 PRO n 
1 456 ALA n 
1 457 TRP n 
1 458 LEU n 
1 459 ARG n 
1 460 PHE n 
1 461 ILE n 
1 462 GLN n 
1 463 CYS n 
1 464 LEU n 
1 465 ARG n 
1 466 ARG n 
1 467 TYR n 
1 468 ARG n 
1 469 ASP n 
1 470 THR n 
1 471 LYS n 
1 472 ARG n 
1 473 ALA n 
1 474 PHE n 
1 475 PRO n 
1 476 HIS n 
1 477 LEU n 
1 478 VAL n 
1 479 ASN n 
1 480 ALA n 
1 481 GLY n 
1 482 LYS n 
1 483 TYR n 
1 484 SER n 
1 485 THR n 
1 486 THR n 
1 487 PHE n 
1 488 PHE n 
1 489 MET n 
1 490 VAL n 
1 491 THR n 
1 492 PHE n 
1 493 ALA n 
1 494 ALA n 
1 495 LEU n 
1 496 TYR n 
1 497 SER n 
1 498 THR n 
1 499 HIS n 
1 500 LYS n 
1 501 GLU n 
1 502 ARG n 
1 503 GLY n 
1 504 HIS n 
1 505 SER n 
1 506 ASP n 
1 507 THR n 
1 508 MET n 
1 509 VAL n 
1 510 PHE n 
1 511 PHE n 
1 512 TYR n 
1 513 LEU n 
1 514 TRP n 
1 515 ILE n 
1 516 VAL n 
1 517 PHE n 
1 518 TYR n 
1 519 ILE n 
1 520 ILE n 
1 521 SER n 
1 522 SER n 
1 523 CYS n 
1 524 TYR n 
1 525 THR n 
1 526 LEU n 
1 527 ILE n 
1 528 TRP n 
1 529 ASP n 
1 530 LEU n 
1 531 LYS n 
1 532 MET n 
1 533 ASP n 
1 534 TRP n 
1 535 GLY n 
1 536 LEU n 
1 537 PHE n 
1 538 ASP n 
1 539 LYS n 
1 540 ASN n 
1 541 ALA n 
1 542 GLY n 
1 543 GLU n 
1 544 ASN n 
1 545 THR n 
1 546 PHE n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLU n 
1 551 ILE n 
1 552 VAL n 
1 553 TYR n 
1 554 PRO n 
1 555 GLN n 
1 556 LYS n 
1 557 ALA n 
1 558 TYR n 
1 559 TYR n 
1 560 TYR n 
1 561 CYS n 
1 562 ALA n 
1 563 ILE n 
1 564 ILE n 
1 565 GLU n 
1 566 ASP n 
1 567 VAL n 
1 568 ILE n 
1 569 LEU n 
1 570 ARG n 
1 571 PHE n 
1 572 ALA n 
1 573 TRP n 
1 574 THR n 
1 575 ILE n 
1 576 GLN n 
1 577 ILE n 
1 578 SER n 
1 579 ILE n 
1 580 THR n 
1 581 SER n 
1 582 THR n 
1 583 THR n 
1 584 LEU n 
1 585 LEU n 
1 586 PRO n 
1 587 HIS n 
1 588 SER n 
1 589 GLY n 
1 590 ASP n 
1 591 ILE n 
1 592 ILE n 
1 593 ALA n 
1 594 THR n 
1 595 VAL n 
1 596 PHE n 
1 597 ALA n 
1 598 PRO n 
1 599 LEU n 
1 600 GLU n 
1 601 VAL n 
1 602 PHE n 
1 603 ARG n 
1 604 ARG n 
1 605 PHE n 
1 606 VAL n 
1 607 TRP n 
1 608 ASN n 
1 609 PHE n 
1 610 PHE n 
1 611 ARG n 
1 612 LEU n 
1 613 GLU n 
1 614 ASN n 
1 615 GLU n 
1 616 HIS n 
1 617 LEU n 
1 618 ASN n 
1 619 ASN n 
1 620 CYS n 
1 621 GLY n 
1 622 GLU n 
1 623 PHE n 
1 624 ARG n 
1 625 ALA n 
1 626 VAL n 
1 627 ARG n 
1 628 ASP n 
1 629 ILE n 
1 630 SER n 
1 631 VAL n 
1 632 ALA n 
1 633 PRO n 
1 634 LEU n 
1 635 ASN n 
1 636 ALA n 
1 637 ASP n 
1 638 ASP n 
1 639 GLN n 
1 640 THR n 
1 641 LEU n 
1 642 LEU n 
1 643 GLU n 
1 644 GLN n 
1 645 MET n 
1 646 MET n 
1 647 ASP n 
1 648 GLN n 
1 649 ASP n 
1 650 ASP n 
1 651 GLY n 
1 652 VAL n 
1 653 ARG n 
1 654 ASN n 
1 655 ARG n 
1 656 GLN n 
1 657 LYS n 
1 658 ASN n 
1 659 ARG n 
1 660 SER n 
1 661 TRP n 
1 662 LYS n 
1 663 TYR n 
1 664 ASN n 
1 665 GLN n 
1 666 SER n 
1 667 ILE n 
1 668 SER n 
1 669 LEU n 
1 670 ARG n 
1 671 ARG n 
1 672 PRO n 
1 673 ARG n 
1 674 LEU n 
1 675 ALA n 
1 676 SER n 
1 677 GLN n 
1 678 SER n 
1 679 LYS n 
1 680 ALA n 
1 681 ARG n 
1 682 ASP n 
1 683 THR n 
1 684 LYS n 
1 685 VAL n 
1 686 LEU n 
1 687 ILE n 
1 688 GLU n 
1 689 ASP n 
1 690 THR n 
1 691 ASP n 
1 692 ASP n 
1 693 GLU n 
1 694 ALA n 
1 695 ASN n 
1 696 THR n 
1 697 LEU n 
1 698 GLU n 
1 699 ASP n 
1 700 TYR n 
1 701 LYS n 
1 702 ASP n 
1 703 HIS n 
1 704 ASP n 
1 705 GLY n 
1 706 ASP n 
1 707 TYR n 
1 708 LYS n 
1 709 ASP n 
1 710 HIS n 
1 711 ASP n 
1 712 ILE n 
1 713 ASP n 
1 714 TYR n 
1 715 LYS n 
1 716 ASP n 
1 717 ASP n 
1 718 ASP n 
1 719 ASP n 
1 720 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   720 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'XPR1, SLC53A1, SYG1, X3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                ?                        'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                               ?                        'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                             ?                        'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                        ?                        'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                               ?                        'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                              ?                        'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                        ?                        'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                ?                        'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                              ?                        'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                             ?                        'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                ?                        'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                 ?                        'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                             ?                        'C5 H11 N O2 S'  149.211 
PC1 non-polymer         . 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE 3-SN-PHOSPHATIDYLCHOLINE 'C44 H88 N O8 P' 790.145 
PHE 'L-peptide linking' y PHENYLALANINE                          ?                        'C9 H11 N O2'    165.189 
PO4 non-polymer         . 'PHOSPHATE ION'                        ?                        'O4 P -3'        94.971  
PRO 'L-peptide linking' y PROLINE                                ?                        'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                 ?                        'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                              ?                        'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                             ?                        'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                               ?                        'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                 ?                        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   ?   ?   ?   A . n 
A 1 3   PHE 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   GLU 5   5   ?   ?   ?   A . n 
A 1 6   HIS 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   SER 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  HIS 10  10  ?   ?   ?   A . n 
A 1 11  ILE 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  PRO 13  13  ?   ?   ?   A . n 
A 1 14  GLU 14  14  ?   ?   ?   A . n 
A 1 15  TRP 15  15  ?   ?   ?   A . n 
A 1 16  ARG 16  16  ?   ?   ?   A . n 
A 1 17  LYS 17  17  ?   ?   ?   A . n 
A 1 18  GLN 18  18  ?   ?   ?   A . n 
A 1 19  TYR 19  19  ?   ?   ?   A . n 
A 1 20  ILE 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  TYR 22  22  ?   ?   ?   A . n 
A 1 23  GLU 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  PHE 25  25  ?   ?   ?   A . n 
A 1 26  LYS 26  26  ?   ?   ?   A . n 
A 1 27  ASP 27  27  ?   ?   ?   A . n 
A 1 28  MET 28  28  ?   ?   ?   A . n 
A 1 29  LEU 29  29  ?   ?   ?   A . n 
A 1 30  TYR 30  30  ?   ?   ?   A . n 
A 1 31  SER 31  31  ?   ?   ?   A . n 
A 1 32  ALA 32  32  ?   ?   ?   A . n 
A 1 33  GLN 33  33  ?   ?   ?   A . n 
A 1 34  ASP 34  34  ?   ?   ?   A . n 
A 1 35  GLN 35  35  ?   ?   ?   A . n 
A 1 36  ALA 36  36  ?   ?   ?   A . n 
A 1 37  PRO 37  37  ?   ?   ?   A . n 
A 1 38  SER 38  38  ?   ?   ?   A . n 
A 1 39  VAL 39  39  ?   ?   ?   A . n 
A 1 40  GLU 40  40  ?   ?   ?   A . n 
A 1 41  VAL 41  41  ?   ?   ?   A . n 
A 1 42  THR 42  42  ?   ?   ?   A . n 
A 1 43  ASP 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  ASP 45  45  ?   ?   ?   A . n 
A 1 46  THR 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  LYS 48  48  ?   ?   ?   A . n 
A 1 49  ARG 49  49  ?   ?   ?   A . n 
A 1 50  TYR 50  50  ?   ?   ?   A . n 
A 1 51  PHE 51  51  ?   ?   ?   A . n 
A 1 52  ALA 52  52  ?   ?   ?   A . n 
A 1 53  LYS 53  53  ?   ?   ?   A . n 
A 1 54  PHE 54  54  ?   ?   ?   A . n 
A 1 55  GLU 55  55  ?   ?   ?   A . n 
A 1 56  GLU 56  56  ?   ?   ?   A . n 
A 1 57  LYS 57  57  ?   ?   ?   A . n 
A 1 58  PHE 58  58  ?   ?   ?   A . n 
A 1 59  PHE 59  59  ?   ?   ?   A . n 
A 1 60  GLN 60  60  ?   ?   ?   A . n 
A 1 61  THR 61  61  ?   ?   ?   A . n 
A 1 62  CYS 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  LYS 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  ALA 67  67  ?   ?   ?   A . n 
A 1 68  LYS 68  68  ?   ?   ?   A . n 
A 1 69  ILE 69  69  ?   ?   ?   A . n 
A 1 70  ASN 70  70  ?   ?   ?   A . n 
A 1 71  THR 71  71  ?   ?   ?   A . n 
A 1 72  PHE 72  72  ?   ?   ?   A . n 
A 1 73  TYR 73  73  ?   ?   ?   A . n 
A 1 74  SER 74  74  ?   ?   ?   A . n 
A 1 75  GLU 75  75  ?   ?   ?   A . n 
A 1 76  LYS 76  76  ?   ?   ?   A . n 
A 1 77  LEU 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  ?   ?   ?   A . n 
A 1 79  GLU 79  79  ?   ?   ?   A . n 
A 1 80  ALA 80  80  ?   ?   ?   A . n 
A 1 81  GLN 81  81  ?   ?   ?   A . n 
A 1 82  ARG 82  82  ?   ?   ?   A . n 
A 1 83  ARG 83  83  ?   ?   ?   A . n 
A 1 84  PHE 84  84  ?   ?   ?   A . n 
A 1 85  ALA 85  85  ?   ?   ?   A . n 
A 1 86  THR 86  86  ?   ?   ?   A . n 
A 1 87  LEU 87  87  ?   ?   ?   A . n 
A 1 88  GLN 88  88  ?   ?   ?   A . n 
A 1 89  ASN 89  89  ?   ?   ?   A . n 
A 1 90  GLU 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  GLN 92  92  ?   ?   ?   A . n 
A 1 93  SER 93  93  ?   ?   ?   A . n 
A 1 94  SER 94  94  ?   ?   ?   A . n 
A 1 95  LEU 95  95  ?   ?   ?   A . n 
A 1 96  ASP 96  96  ?   ?   ?   A . n 
A 1 97  ALA 97  97  ?   ?   ?   A . n 
A 1 98  GLN 98  98  ?   ?   ?   A . n 
A 1 99  LYS 99  99  ?   ?   ?   A . n 
A 1 100 GLU 100 100 ?   ?   ?   A . n 
A 1 101 SER 101 101 ?   ?   ?   A . n 
A 1 102 THR 102 102 ?   ?   ?   A . n 
A 1 103 GLY 103 103 ?   ?   ?   A . n 
A 1 104 VAL 104 104 ?   ?   ?   A . n 
A 1 105 THR 105 105 ?   ?   ?   A . n 
A 1 106 THR 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 ARG 108 108 ?   ?   ?   A . n 
A 1 109 GLN 109 109 ?   ?   ?   A . n 
A 1 110 ARG 110 110 ?   ?   ?   A . n 
A 1 111 ARG 111 111 ?   ?   ?   A . n 
A 1 112 LYS 112 112 ?   ?   ?   A . n 
A 1 113 PRO 113 113 ?   ?   ?   A . n 
A 1 114 VAL 114 114 ?   ?   ?   A . n 
A 1 115 PHE 115 115 ?   ?   ?   A . n 
A 1 116 HIS 116 116 ?   ?   ?   A . n 
A 1 117 LEU 117 117 ?   ?   ?   A . n 
A 1 118 SER 118 118 ?   ?   ?   A . n 
A 1 119 HIS 119 119 ?   ?   ?   A . n 
A 1 120 GLU 120 120 ?   ?   ?   A . n 
A 1 121 GLU 121 121 ?   ?   ?   A . n 
A 1 122 ARG 122 122 ?   ?   ?   A . n 
A 1 123 VAL 123 123 ?   ?   ?   A . n 
A 1 124 GLN 124 124 ?   ?   ?   A . n 
A 1 125 HIS 125 125 ?   ?   ?   A . n 
A 1 126 ARG 126 126 ?   ?   ?   A . n 
A 1 127 ASN 127 127 ?   ?   ?   A . n 
A 1 128 ILE 128 128 ?   ?   ?   A . n 
A 1 129 LYS 129 129 ?   ?   ?   A . n 
A 1 130 ASP 130 130 ?   ?   ?   A . n 
A 1 131 LEU 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 LEU 133 133 ?   ?   ?   A . n 
A 1 134 ALA 134 134 ?   ?   ?   A . n 
A 1 135 PHE 135 135 ?   ?   ?   A . n 
A 1 136 SER 136 136 ?   ?   ?   A . n 
A 1 137 GLU 137 137 ?   ?   ?   A . n 
A 1 138 PHE 138 138 ?   ?   ?   A . n 
A 1 139 TYR 139 139 ?   ?   ?   A . n 
A 1 140 LEU 140 140 ?   ?   ?   A . n 
A 1 141 SER 141 141 ?   ?   ?   A . n 
A 1 142 LEU 142 142 ?   ?   ?   A . n 
A 1 143 ILE 143 143 ?   ?   ?   A . n 
A 1 144 LEU 144 144 ?   ?   ?   A . n 
A 1 145 LEU 145 145 ?   ?   ?   A . n 
A 1 146 GLN 146 146 ?   ?   ?   A . n 
A 1 147 ASN 147 147 ?   ?   ?   A . n 
A 1 148 TYR 148 148 ?   ?   ?   A . n 
A 1 149 GLN 149 149 ?   ?   ?   A . n 
A 1 150 ASN 150 150 ?   ?   ?   A . n 
A 1 151 LEU 151 151 ?   ?   ?   A . n 
A 1 152 ASN 152 152 ?   ?   ?   A . n 
A 1 153 PHE 153 153 ?   ?   ?   A . n 
A 1 154 THR 154 154 ?   ?   ?   A . n 
A 1 155 GLY 155 155 ?   ?   ?   A . n 
A 1 156 PHE 156 156 ?   ?   ?   A . n 
A 1 157 ARG 157 157 ?   ?   ?   A . n 
A 1 158 LYS 158 158 ?   ?   ?   A . n 
A 1 159 ILE 159 159 ?   ?   ?   A . n 
A 1 160 LEU 160 160 ?   ?   ?   A . n 
A 1 161 LYS 161 161 ?   ?   ?   A . n 
A 1 162 LYS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 ASP 164 164 ?   ?   ?   A . n 
A 1 165 LYS 165 165 ?   ?   ?   A . n 
A 1 166 ILE 166 166 ?   ?   ?   A . n 
A 1 167 LEU 167 167 ?   ?   ?   A . n 
A 1 168 GLU 168 168 ?   ?   ?   A . n 
A 1 169 THR 169 169 ?   ?   ?   A . n 
A 1 170 SER 170 170 ?   ?   ?   A . n 
A 1 171 ARG 171 171 ?   ?   ?   A . n 
A 1 172 GLY 172 172 ?   ?   ?   A . n 
A 1 173 ALA 173 173 ?   ?   ?   A . n 
A 1 174 ASP 174 174 ?   ?   ?   A . n 
A 1 175 TRP 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 VAL 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 HIS 179 179 ?   ?   ?   A . n 
A 1 180 VAL 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
A 1 182 VAL 182 182 ?   ?   ?   A . n 
A 1 183 ALA 183 183 ?   ?   ?   A . n 
A 1 184 PRO 184 184 ?   ?   ?   A . n 
A 1 185 PHE 185 185 ?   ?   ?   A . n 
A 1 186 TYR 186 186 ?   ?   ?   A . n 
A 1 187 THR 187 187 ?   ?   ?   A . n 
A 1 188 CYS 188 188 ?   ?   ?   A . n 
A 1 189 LYS 189 189 ?   ?   ?   A . n 
A 1 190 LYS 190 190 ?   ?   ?   A . n 
A 1 191 ILE 191 191 ?   ?   ?   A . n 
A 1 192 ASN 192 192 ?   ?   ?   A . n 
A 1 193 GLN 193 193 ?   ?   ?   A . n 
A 1 194 LEU 194 194 ?   ?   ?   A . n 
A 1 195 ILE 195 195 ?   ?   ?   A . n 
A 1 196 SER 196 196 ?   ?   ?   A . n 
A 1 197 GLU 197 197 ?   ?   ?   A . n 
A 1 198 THR 198 198 ?   ?   ?   A . n 
A 1 199 GLU 199 199 ?   ?   ?   A . n 
A 1 200 ALA 200 200 ?   ?   ?   A . n 
A 1 201 VAL 201 201 ?   ?   ?   A . n 
A 1 202 VAL 202 202 ?   ?   ?   A . n 
A 1 203 THR 203 203 ?   ?   ?   A . n 
A 1 204 ASN 204 204 ?   ?   ?   A . n 
A 1 205 GLU 205 205 ?   ?   ?   A . n 
A 1 206 LEU 206 206 ?   ?   ?   A . n 
A 1 207 GLU 207 207 ?   ?   ?   A . n 
A 1 208 ASP 208 208 ?   ?   ?   A . n 
A 1 209 GLY 209 209 ?   ?   ?   A . n 
A 1 210 ASP 210 210 ?   ?   ?   A . n 
A 1 211 ARG 211 211 ?   ?   ?   A . n 
A 1 212 GLN 212 212 ?   ?   ?   A . n 
A 1 213 LYS 213 213 ?   ?   ?   A . n 
A 1 214 ALA 214 214 ?   ?   ?   A . n 
A 1 215 MET 215 215 ?   ?   ?   A . n 
A 1 216 LYS 216 216 ?   ?   ?   A . n 
A 1 217 ARG 217 217 ?   ?   ?   A . n 
A 1 218 LEU 218 218 ?   ?   ?   A . n 
A 1 219 ARG 219 219 ?   ?   ?   A . n 
A 1 220 VAL 220 220 ?   ?   ?   A . n 
A 1 221 PRO 221 221 ?   ?   ?   A . n 
A 1 222 PRO 222 222 ?   ?   ?   A . n 
A 1 223 LEU 223 223 ?   ?   ?   A . n 
A 1 224 GLY 224 224 ?   ?   ?   A . n 
A 1 225 ALA 225 225 ?   ?   ?   A . n 
A 1 226 ALA 226 226 ?   ?   ?   A . n 
A 1 227 GLN 227 227 ?   ?   ?   A . n 
A 1 228 PRO 228 228 ?   ?   ?   A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 THR 233 233 233 THR THR A . n 
A 1 234 THR 234 234 234 THR THR A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 ARG 236 236 236 ARG ARG A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 CYS 241 241 241 CYS CYS A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 LYS 258 258 258 LYS LYS A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 GLU 260 260 260 GLU GLU A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 TRP 266 266 266 TRP TRP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 TYR 272 272 272 TYR TYR A . n 
A 1 273 ARG 273 273 273 ARG ARG A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 PHE 276 276 276 PHE PHE A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 PHE 283 283 283 PHE PHE A . n 
A 1 284 LEU 284 284 284 LEU LEU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLY 286 286 286 GLY GLY A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 THR 289 289 289 THR THR A . n 
A 1 290 TYR 290 290 290 TYR TYR A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 TRP 292 292 292 TRP TRP A . n 
A 1 293 ARG 293 293 293 ARG ARG A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 HIS 299 299 299 HIS HIS A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 HIS 315 315 315 HIS HIS A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 PHE 317 317 317 PHE PHE A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 GLY 324 324 324 GLY GLY A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 CYS 328 328 328 CYS CYS A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 SER 330 330 330 SER SER A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 VAL 341 341 341 VAL VAL A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 THR 344 344 344 THR THR A . n 
A 1 345 TYR 345 345 345 TYR TYR A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 TYR 347 347 347 TYR TYR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 TYR 352 352 352 TYR TYR A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
A 1 355 MET 355 355 355 MET MET A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 ASN 361 361 361 ASN ASN A . n 
A 1 362 PRO 362 362 362 PRO PRO A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 LYS 364 364 364 LYS LYS A . n 
A 1 365 THR 365 365 365 THR THR A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 TYR 367 367 367 TYR TYR A . n 
A 1 368 TYR 368 368 368 TYR TYR A . n 
A 1 369 LYS 369 369 369 LYS LYS A . n 
A 1 370 SER 370 370 370 SER SER A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 TRP 373 373 373 TRP TRP A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ARG 380 380 380 ARG ARG A . n 
A 1 381 VAL 381 381 381 VAL VAL A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 ALA 384 384 384 ALA ALA A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 GLY 390 390 390 GLY GLY A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 ASP 393 393 393 ASP ASP A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 TRP 395 395 395 TRP TRP A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 ASP 398 398 398 ASP ASP A . n 
A 1 399 GLN 399 399 399 GLN GLN A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ASN 401 401 401 ASN ASN A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 VAL 405 405 405 VAL VAL A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 LEU 407 407 407 LEU LEU A . n 
A 1 408 MET 408 408 408 MET MET A . n 
A 1 409 ASP 409 409 409 ASP ASP A . n 
A 1 410 LEU 410 410 410 LEU LEU A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 MET 413 413 413 MET MET A . n 
A 1 414 ILE 414 414 414 ILE ILE A . n 
A 1 415 CYS 415 415 415 CYS CYS A . n 
A 1 416 PHE 416 416 416 PHE PHE A . n 
A 1 417 TYR 417 417 417 TYR TYR A . n 
A 1 418 SER 418 418 418 SER SER A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 LYS 422 422 422 LYS LYS A . n 
A 1 423 TRP 423 423 423 TRP TRP A . n 
A 1 424 ASP 424 424 424 ASP ASP A . n 
A 1 425 GLU 425 425 425 GLU GLU A . n 
A 1 426 SER 426 426 426 SER SER A . n 
A 1 427 LYS 427 427 427 LYS LYS A . n 
A 1 428 GLY 428 428 428 GLY GLY A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 PRO 431 431 431 PRO PRO A . n 
A 1 432 ASN 432 432 ?   ?   ?   A . n 
A 1 433 ASN 433 433 ?   ?   ?   A . n 
A 1 434 SER 434 434 ?   ?   ?   A . n 
A 1 435 GLU 435 435 ?   ?   ?   A . n 
A 1 436 GLU 436 436 ?   ?   ?   A . n 
A 1 437 SER 437 437 ?   ?   ?   A . n 
A 1 438 GLY 438 438 ?   ?   ?   A . n 
A 1 439 ILE 439 439 ?   ?   ?   A . n 
A 1 440 CYS 440 440 ?   ?   ?   A . n 
A 1 441 HIS 441 441 ?   ?   ?   A . n 
A 1 442 LYS 442 442 ?   ?   ?   A . n 
A 1 443 TYR 443 443 ?   ?   ?   A . n 
A 1 444 THR 444 444 ?   ?   ?   A . n 
A 1 445 TYR 445 445 ?   ?   ?   A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 ARG 448 448 448 ARG ARG A . n 
A 1 449 ALA 449 449 449 ALA ALA A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 VAL 451 451 451 VAL VAL A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 CYS 453 453 453 CYS CYS A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 PRO 455 455 455 PRO PRO A . n 
A 1 456 ALA 456 456 456 ALA ALA A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 LEU 458 458 458 LEU LEU A . n 
A 1 459 ARG 459 459 459 ARG ARG A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 ILE 461 461 461 ILE ILE A . n 
A 1 462 GLN 462 462 462 GLN GLN A . n 
A 1 463 CYS 463 463 463 CYS CYS A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 ARG 465 465 465 ARG ARG A . n 
A 1 466 ARG 466 466 466 ARG ARG A . n 
A 1 467 TYR 467 467 467 TYR TYR A . n 
A 1 468 ARG 468 468 468 ARG ARG A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 LYS 471 471 471 LYS LYS A . n 
A 1 472 ARG 472 472 472 ARG ARG A . n 
A 1 473 ALA 473 473 473 ALA ALA A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 PRO 475 475 475 PRO PRO A . n 
A 1 476 HIS 476 476 476 HIS HIS A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 ASN 479 479 479 ASN ASN A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 GLY 481 481 481 GLY GLY A . n 
A 1 482 LYS 482 482 482 LYS LYS A . n 
A 1 483 TYR 483 483 483 TYR TYR A . n 
A 1 484 SER 484 484 484 SER SER A . n 
A 1 485 THR 485 485 485 THR THR A . n 
A 1 486 THR 486 486 486 THR THR A . n 
A 1 487 PHE 487 487 487 PHE PHE A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 MET 489 489 489 MET MET A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
A 1 491 THR 491 491 491 THR THR A . n 
A 1 492 PHE 492 492 492 PHE PHE A . n 
A 1 493 ALA 493 493 493 ALA ALA A . n 
A 1 494 ALA 494 494 494 ALA ALA A . n 
A 1 495 LEU 495 495 495 LEU LEU A . n 
A 1 496 TYR 496 496 496 TYR TYR A . n 
A 1 497 SER 497 497 497 SER SER A . n 
A 1 498 THR 498 498 498 THR THR A . n 
A 1 499 HIS 499 499 499 HIS HIS A . n 
A 1 500 LYS 500 500 500 LYS LYS A . n 
A 1 501 GLU 501 501 501 GLU GLU A . n 
A 1 502 ARG 502 502 502 ARG ARG A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 HIS 504 504 504 HIS HIS A . n 
A 1 505 SER 505 505 505 SER SER A . n 
A 1 506 ASP 506 506 506 ASP ASP A . n 
A 1 507 THR 507 507 507 THR THR A . n 
A 1 508 MET 508 508 508 MET MET A . n 
A 1 509 VAL 509 509 509 VAL VAL A . n 
A 1 510 PHE 510 510 510 PHE PHE A . n 
A 1 511 PHE 511 511 511 PHE PHE A . n 
A 1 512 TYR 512 512 512 TYR TYR A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 VAL 516 516 516 VAL VAL A . n 
A 1 517 PHE 517 517 517 PHE PHE A . n 
A 1 518 TYR 518 518 518 TYR TYR A . n 
A 1 519 ILE 519 519 519 ILE ILE A . n 
A 1 520 ILE 520 520 520 ILE ILE A . n 
A 1 521 SER 521 521 521 SER SER A . n 
A 1 522 SER 522 522 522 SER SER A . n 
A 1 523 CYS 523 523 523 CYS CYS A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 THR 525 525 525 THR THR A . n 
A 1 526 LEU 526 526 526 LEU LEU A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 TRP 528 528 528 TRP TRP A . n 
A 1 529 ASP 529 529 529 ASP ASP A . n 
A 1 530 LEU 530 530 530 LEU LEU A . n 
A 1 531 LYS 531 531 531 LYS LYS A . n 
A 1 532 MET 532 532 532 MET MET A . n 
A 1 533 ASP 533 533 533 ASP ASP A . n 
A 1 534 TRP 534 534 534 TRP TRP A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 LEU 536 536 536 LEU LEU A . n 
A 1 537 PHE 537 537 537 PHE PHE A . n 
A 1 538 ASP 538 538 538 ASP ASP A . n 
A 1 539 LYS 539 539 539 LYS LYS A . n 
A 1 540 ASN 540 540 540 ASN ASN A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 GLY 542 542 542 GLY GLY A . n 
A 1 543 GLU 543 543 543 GLU GLU A . n 
A 1 544 ASN 544 544 544 ASN ASN A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 PHE 546 546 546 PHE PHE A . n 
A 1 547 LEU 547 547 547 LEU LEU A . n 
A 1 548 ARG 548 548 548 ARG ARG A . n 
A 1 549 GLU 549 549 549 GLU GLU A . n 
A 1 550 GLU 550 550 550 GLU GLU A . n 
A 1 551 ILE 551 551 551 ILE ILE A . n 
A 1 552 VAL 552 552 552 VAL VAL A . n 
A 1 553 TYR 553 553 553 TYR TYR A . n 
A 1 554 PRO 554 554 554 PRO PRO A . n 
A 1 555 GLN 555 555 555 GLN GLN A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 TYR 558 558 558 TYR TYR A . n 
A 1 559 TYR 559 559 559 TYR TYR A . n 
A 1 560 TYR 560 560 560 TYR TYR A . n 
A 1 561 CYS 561 561 561 CYS CYS A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 ILE 564 564 564 ILE ILE A . n 
A 1 565 GLU 565 565 565 GLU GLU A . n 
A 1 566 ASP 566 566 566 ASP ASP A . n 
A 1 567 VAL 567 567 567 VAL VAL A . n 
A 1 568 ILE 568 568 568 ILE ILE A . n 
A 1 569 LEU 569 569 569 LEU LEU A . n 
A 1 570 ARG 570 570 570 ARG ARG A . n 
A 1 571 PHE 571 571 571 PHE PHE A . n 
A 1 572 ALA 572 572 572 ALA ALA A . n 
A 1 573 TRP 573 573 573 TRP TRP A . n 
A 1 574 THR 574 574 574 THR THR A . n 
A 1 575 ILE 575 575 575 ILE ILE A . n 
A 1 576 GLN 576 576 576 GLN GLN A . n 
A 1 577 ILE 577 577 577 ILE ILE A . n 
A 1 578 SER 578 578 578 SER SER A . n 
A 1 579 ILE 579 579 579 ILE ILE A . n 
A 1 580 THR 580 580 580 THR THR A . n 
A 1 581 SER 581 581 581 SER SER A . n 
A 1 582 THR 582 582 582 THR THR A . n 
A 1 583 THR 583 583 583 THR THR A . n 
A 1 584 LEU 584 584 584 LEU LEU A . n 
A 1 585 LEU 585 585 585 LEU LEU A . n 
A 1 586 PRO 586 586 586 PRO PRO A . n 
A 1 587 HIS 587 587 587 HIS HIS A . n 
A 1 588 SER 588 588 588 SER SER A . n 
A 1 589 GLY 589 589 589 GLY GLY A . n 
A 1 590 ASP 590 590 590 ASP ASP A . n 
A 1 591 ILE 591 591 591 ILE ILE A . n 
A 1 592 ILE 592 592 592 ILE ILE A . n 
A 1 593 ALA 593 593 593 ALA ALA A . n 
A 1 594 THR 594 594 594 THR THR A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 PHE 596 596 596 PHE PHE A . n 
A 1 597 ALA 597 597 597 ALA ALA A . n 
A 1 598 PRO 598 598 598 PRO PRO A . n 
A 1 599 LEU 599 599 599 LEU LEU A . n 
A 1 600 GLU 600 600 600 GLU GLU A . n 
A 1 601 VAL 601 601 601 VAL VAL A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 ARG 603 603 603 ARG ARG A . n 
A 1 604 ARG 604 604 604 ARG ARG A . n 
A 1 605 PHE 605 605 605 PHE PHE A . n 
A 1 606 VAL 606 606 606 VAL VAL A . n 
A 1 607 TRP 607 607 607 TRP TRP A . n 
A 1 608 ASN 608 608 608 ASN ASN A . n 
A 1 609 PHE 609 609 609 PHE PHE A . n 
A 1 610 PHE 610 610 610 PHE PHE A . n 
A 1 611 ARG 611 611 611 ARG ARG A . n 
A 1 612 LEU 612 612 612 LEU LEU A . n 
A 1 613 GLU 613 613 613 GLU GLU A . n 
A 1 614 ASN 614 614 614 ASN ASN A . n 
A 1 615 GLU 615 615 615 GLU GLU A . n 
A 1 616 HIS 616 616 616 HIS HIS A . n 
A 1 617 LEU 617 617 617 LEU LEU A . n 
A 1 618 ASN 618 618 618 ASN ASN A . n 
A 1 619 ASN 619 619 619 ASN ASN A . n 
A 1 620 CYS 620 620 620 CYS CYS A . n 
A 1 621 GLY 621 621 621 GLY GLY A . n 
A 1 622 GLU 622 622 622 GLU GLU A . n 
A 1 623 PHE 623 623 623 PHE PHE A . n 
A 1 624 ARG 624 624 624 ARG ARG A . n 
A 1 625 ALA 625 625 ?   ?   ?   A . n 
A 1 626 VAL 626 626 ?   ?   ?   A . n 
A 1 627 ARG 627 627 ?   ?   ?   A . n 
A 1 628 ASP 628 628 ?   ?   ?   A . n 
A 1 629 ILE 629 629 ?   ?   ?   A . n 
A 1 630 SER 630 630 ?   ?   ?   A . n 
A 1 631 VAL 631 631 ?   ?   ?   A . n 
A 1 632 ALA 632 632 ?   ?   ?   A . n 
A 1 633 PRO 633 633 ?   ?   ?   A . n 
A 1 634 LEU 634 634 ?   ?   ?   A . n 
A 1 635 ASN 635 635 ?   ?   ?   A . n 
A 1 636 ALA 636 636 ?   ?   ?   A . n 
A 1 637 ASP 637 637 ?   ?   ?   A . n 
A 1 638 ASP 638 638 ?   ?   ?   A . n 
A 1 639 GLN 639 639 ?   ?   ?   A . n 
A 1 640 THR 640 640 ?   ?   ?   A . n 
A 1 641 LEU 641 641 ?   ?   ?   A . n 
A 1 642 LEU 642 642 ?   ?   ?   A . n 
A 1 643 GLU 643 643 ?   ?   ?   A . n 
A 1 644 GLN 644 644 ?   ?   ?   A . n 
A 1 645 MET 645 645 ?   ?   ?   A . n 
A 1 646 MET 646 646 ?   ?   ?   A . n 
A 1 647 ASP 647 647 ?   ?   ?   A . n 
A 1 648 GLN 648 648 ?   ?   ?   A . n 
A 1 649 ASP 649 649 ?   ?   ?   A . n 
A 1 650 ASP 650 650 ?   ?   ?   A . n 
A 1 651 GLY 651 651 ?   ?   ?   A . n 
A 1 652 VAL 652 652 ?   ?   ?   A . n 
A 1 653 ARG 653 653 ?   ?   ?   A . n 
A 1 654 ASN 654 654 ?   ?   ?   A . n 
A 1 655 ARG 655 655 ?   ?   ?   A . n 
A 1 656 GLN 656 656 ?   ?   ?   A . n 
A 1 657 LYS 657 657 ?   ?   ?   A . n 
A 1 658 ASN 658 658 ?   ?   ?   A . n 
A 1 659 ARG 659 659 ?   ?   ?   A . n 
A 1 660 SER 660 660 ?   ?   ?   A . n 
A 1 661 TRP 661 661 ?   ?   ?   A . n 
A 1 662 LYS 662 662 ?   ?   ?   A . n 
A 1 663 TYR 663 663 ?   ?   ?   A . n 
A 1 664 ASN 664 664 ?   ?   ?   A . n 
A 1 665 GLN 665 665 ?   ?   ?   A . n 
A 1 666 SER 666 666 ?   ?   ?   A . n 
A 1 667 ILE 667 667 ?   ?   ?   A . n 
A 1 668 SER 668 668 ?   ?   ?   A . n 
A 1 669 LEU 669 669 ?   ?   ?   A . n 
A 1 670 ARG 670 670 ?   ?   ?   A . n 
A 1 671 ARG 671 671 ?   ?   ?   A . n 
A 1 672 PRO 672 672 ?   ?   ?   A . n 
A 1 673 ARG 673 673 ?   ?   ?   A . n 
A 1 674 LEU 674 674 ?   ?   ?   A . n 
A 1 675 ALA 675 675 ?   ?   ?   A . n 
A 1 676 SER 676 676 ?   ?   ?   A . n 
A 1 677 GLN 677 677 ?   ?   ?   A . n 
A 1 678 SER 678 678 ?   ?   ?   A . n 
A 1 679 LYS 679 679 ?   ?   ?   A . n 
A 1 680 ALA 680 680 ?   ?   ?   A . n 
A 1 681 ARG 681 681 ?   ?   ?   A . n 
A 1 682 ASP 682 682 ?   ?   ?   A . n 
A 1 683 THR 683 683 ?   ?   ?   A . n 
A 1 684 LYS 684 684 ?   ?   ?   A . n 
A 1 685 VAL 685 685 ?   ?   ?   A . n 
A 1 686 LEU 686 686 ?   ?   ?   A . n 
A 1 687 ILE 687 687 ?   ?   ?   A . n 
A 1 688 GLU 688 688 ?   ?   ?   A . n 
A 1 689 ASP 689 689 ?   ?   ?   A . n 
A 1 690 THR 690 690 ?   ?   ?   A . n 
A 1 691 ASP 691 691 ?   ?   ?   A . n 
A 1 692 ASP 692 692 ?   ?   ?   A . n 
A 1 693 GLU 693 693 ?   ?   ?   A . n 
A 1 694 ALA 694 694 ?   ?   ?   A . n 
A 1 695 ASN 695 695 ?   ?   ?   A . n 
A 1 696 THR 696 696 ?   ?   ?   A . n 
A 1 697 LEU 697 697 ?   ?   ?   A . n 
A 1 698 GLU 698 698 ?   ?   ?   A . n 
A 1 699 ASP 699 699 ?   ?   ?   A . n 
A 1 700 TYR 700 700 ?   ?   ?   A . n 
A 1 701 LYS 701 701 ?   ?   ?   A . n 
A 1 702 ASP 702 702 ?   ?   ?   A . n 
A 1 703 HIS 703 703 ?   ?   ?   A . n 
A 1 704 ASP 704 704 ?   ?   ?   A . n 
A 1 705 GLY 705 705 ?   ?   ?   A . n 
A 1 706 ASP 706 706 ?   ?   ?   A . n 
A 1 707 TYR 707 707 ?   ?   ?   A . n 
A 1 708 LYS 708 708 ?   ?   ?   A . n 
A 1 709 ASP 709 709 ?   ?   ?   A . n 
A 1 710 HIS 710 710 ?   ?   ?   A . n 
A 1 711 ASP 711 711 ?   ?   ?   A . n 
A 1 712 ILE 712 712 ?   ?   ?   A . n 
A 1 713 ASP 713 713 ?   ?   ?   A . n 
A 1 714 TYR 714 714 ?   ?   ?   A . n 
A 1 715 LYS 715 715 ?   ?   ?   A . n 
A 1 716 ASP 716 716 ?   ?   ?   A . n 
A 1 717 ASP 717 717 ?   ?   ?   A . n 
A 1 718 ASP 718 718 ?   ?   ?   A . n 
A 1 719 ASP 719 719 ?   ?   ?   A . n 
A 1 720 LYS 720 720 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   LYS 2   2   ?   ?   ?   B . n 
B 1 3   PHE 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   GLU 5   5   ?   ?   ?   B . n 
B 1 6   HIS 6   6   ?   ?   ?   B . n 
B 1 7   LEU 7   7   ?   ?   ?   B . n 
B 1 8   SER 8   8   ?   ?   ?   B . n 
B 1 9   ALA 9   9   ?   ?   ?   B . n 
B 1 10  HIS 10  10  ?   ?   ?   B . n 
B 1 11  ILE 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  PRO 13  13  ?   ?   ?   B . n 
B 1 14  GLU 14  14  ?   ?   ?   B . n 
B 1 15  TRP 15  15  ?   ?   ?   B . n 
B 1 16  ARG 16  16  ?   ?   ?   B . n 
B 1 17  LYS 17  17  ?   ?   ?   B . n 
B 1 18  GLN 18  18  ?   ?   ?   B . n 
B 1 19  TYR 19  19  ?   ?   ?   B . n 
B 1 20  ILE 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  TYR 22  22  ?   ?   ?   B . n 
B 1 23  GLU 23  23  ?   ?   ?   B . n 
B 1 24  ALA 24  24  ?   ?   ?   B . n 
B 1 25  PHE 25  25  ?   ?   ?   B . n 
B 1 26  LYS 26  26  ?   ?   ?   B . n 
B 1 27  ASP 27  27  ?   ?   ?   B . n 
B 1 28  MET 28  28  ?   ?   ?   B . n 
B 1 29  LEU 29  29  ?   ?   ?   B . n 
B 1 30  TYR 30  30  ?   ?   ?   B . n 
B 1 31  SER 31  31  ?   ?   ?   B . n 
B 1 32  ALA 32  32  ?   ?   ?   B . n 
B 1 33  GLN 33  33  ?   ?   ?   B . n 
B 1 34  ASP 34  34  ?   ?   ?   B . n 
B 1 35  GLN 35  35  ?   ?   ?   B . n 
B 1 36  ALA 36  36  ?   ?   ?   B . n 
B 1 37  PRO 37  37  ?   ?   ?   B . n 
B 1 38  SER 38  38  ?   ?   ?   B . n 
B 1 39  VAL 39  39  ?   ?   ?   B . n 
B 1 40  GLU 40  40  ?   ?   ?   B . n 
B 1 41  VAL 41  41  ?   ?   ?   B . n 
B 1 42  THR 42  42  ?   ?   ?   B . n 
B 1 43  ASP 43  43  ?   ?   ?   B . n 
B 1 44  GLU 44  44  ?   ?   ?   B . n 
B 1 45  ASP 45  45  ?   ?   ?   B . n 
B 1 46  THR 46  46  ?   ?   ?   B . n 
B 1 47  VAL 47  47  ?   ?   ?   B . n 
B 1 48  LYS 48  48  ?   ?   ?   B . n 
B 1 49  ARG 49  49  ?   ?   ?   B . n 
B 1 50  TYR 50  50  ?   ?   ?   B . n 
B 1 51  PHE 51  51  ?   ?   ?   B . n 
B 1 52  ALA 52  52  ?   ?   ?   B . n 
B 1 53  LYS 53  53  ?   ?   ?   B . n 
B 1 54  PHE 54  54  ?   ?   ?   B . n 
B 1 55  GLU 55  55  ?   ?   ?   B . n 
B 1 56  GLU 56  56  ?   ?   ?   B . n 
B 1 57  LYS 57  57  ?   ?   ?   B . n 
B 1 58  PHE 58  58  ?   ?   ?   B . n 
B 1 59  PHE 59  59  ?   ?   ?   B . n 
B 1 60  GLN 60  60  ?   ?   ?   B . n 
B 1 61  THR 61  61  ?   ?   ?   B . n 
B 1 62  CYS 62  62  ?   ?   ?   B . n 
B 1 63  GLU 63  63  ?   ?   ?   B . n 
B 1 64  LYS 64  64  ?   ?   ?   B . n 
B 1 65  GLU 65  65  ?   ?   ?   B . n 
B 1 66  LEU 66  66  ?   ?   ?   B . n 
B 1 67  ALA 67  67  ?   ?   ?   B . n 
B 1 68  LYS 68  68  ?   ?   ?   B . n 
B 1 69  ILE 69  69  ?   ?   ?   B . n 
B 1 70  ASN 70  70  ?   ?   ?   B . n 
B 1 71  THR 71  71  ?   ?   ?   B . n 
B 1 72  PHE 72  72  ?   ?   ?   B . n 
B 1 73  TYR 73  73  ?   ?   ?   B . n 
B 1 74  SER 74  74  ?   ?   ?   B . n 
B 1 75  GLU 75  75  ?   ?   ?   B . n 
B 1 76  LYS 76  76  ?   ?   ?   B . n 
B 1 77  LEU 77  77  ?   ?   ?   B . n 
B 1 78  ALA 78  78  ?   ?   ?   B . n 
B 1 79  GLU 79  79  ?   ?   ?   B . n 
B 1 80  ALA 80  80  ?   ?   ?   B . n 
B 1 81  GLN 81  81  ?   ?   ?   B . n 
B 1 82  ARG 82  82  ?   ?   ?   B . n 
B 1 83  ARG 83  83  ?   ?   ?   B . n 
B 1 84  PHE 84  84  ?   ?   ?   B . n 
B 1 85  ALA 85  85  ?   ?   ?   B . n 
B 1 86  THR 86  86  ?   ?   ?   B . n 
B 1 87  LEU 87  87  ?   ?   ?   B . n 
B 1 88  GLN 88  88  ?   ?   ?   B . n 
B 1 89  ASN 89  89  ?   ?   ?   B . n 
B 1 90  GLU 90  90  ?   ?   ?   B . n 
B 1 91  LEU 91  91  ?   ?   ?   B . n 
B 1 92  GLN 92  92  ?   ?   ?   B . n 
B 1 93  SER 93  93  ?   ?   ?   B . n 
B 1 94  SER 94  94  ?   ?   ?   B . n 
B 1 95  LEU 95  95  ?   ?   ?   B . n 
B 1 96  ASP 96  96  ?   ?   ?   B . n 
B 1 97  ALA 97  97  ?   ?   ?   B . n 
B 1 98  GLN 98  98  ?   ?   ?   B . n 
B 1 99  LYS 99  99  ?   ?   ?   B . n 
B 1 100 GLU 100 100 ?   ?   ?   B . n 
B 1 101 SER 101 101 ?   ?   ?   B . n 
B 1 102 THR 102 102 ?   ?   ?   B . n 
B 1 103 GLY 103 103 ?   ?   ?   B . n 
B 1 104 VAL 104 104 ?   ?   ?   B . n 
B 1 105 THR 105 105 ?   ?   ?   B . n 
B 1 106 THR 106 106 ?   ?   ?   B . n 
B 1 107 LEU 107 107 ?   ?   ?   B . n 
B 1 108 ARG 108 108 ?   ?   ?   B . n 
B 1 109 GLN 109 109 ?   ?   ?   B . n 
B 1 110 ARG 110 110 ?   ?   ?   B . n 
B 1 111 ARG 111 111 ?   ?   ?   B . n 
B 1 112 LYS 112 112 ?   ?   ?   B . n 
B 1 113 PRO 113 113 ?   ?   ?   B . n 
B 1 114 VAL 114 114 ?   ?   ?   B . n 
B 1 115 PHE 115 115 ?   ?   ?   B . n 
B 1 116 HIS 116 116 ?   ?   ?   B . n 
B 1 117 LEU 117 117 ?   ?   ?   B . n 
B 1 118 SER 118 118 ?   ?   ?   B . n 
B 1 119 HIS 119 119 ?   ?   ?   B . n 
B 1 120 GLU 120 120 ?   ?   ?   B . n 
B 1 121 GLU 121 121 ?   ?   ?   B . n 
B 1 122 ARG 122 122 ?   ?   ?   B . n 
B 1 123 VAL 123 123 ?   ?   ?   B . n 
B 1 124 GLN 124 124 ?   ?   ?   B . n 
B 1 125 HIS 125 125 ?   ?   ?   B . n 
B 1 126 ARG 126 126 ?   ?   ?   B . n 
B 1 127 ASN 127 127 ?   ?   ?   B . n 
B 1 128 ILE 128 128 ?   ?   ?   B . n 
B 1 129 LYS 129 129 ?   ?   ?   B . n 
B 1 130 ASP 130 130 ?   ?   ?   B . n 
B 1 131 LEU 131 131 ?   ?   ?   B . n 
B 1 132 LYS 132 132 ?   ?   ?   B . n 
B 1 133 LEU 133 133 ?   ?   ?   B . n 
B 1 134 ALA 134 134 ?   ?   ?   B . n 
B 1 135 PHE 135 135 ?   ?   ?   B . n 
B 1 136 SER 136 136 ?   ?   ?   B . n 
B 1 137 GLU 137 137 ?   ?   ?   B . n 
B 1 138 PHE 138 138 ?   ?   ?   B . n 
B 1 139 TYR 139 139 ?   ?   ?   B . n 
B 1 140 LEU 140 140 ?   ?   ?   B . n 
B 1 141 SER 141 141 ?   ?   ?   B . n 
B 1 142 LEU 142 142 ?   ?   ?   B . n 
B 1 143 ILE 143 143 ?   ?   ?   B . n 
B 1 144 LEU 144 144 ?   ?   ?   B . n 
B 1 145 LEU 145 145 ?   ?   ?   B . n 
B 1 146 GLN 146 146 ?   ?   ?   B . n 
B 1 147 ASN 147 147 ?   ?   ?   B . n 
B 1 148 TYR 148 148 ?   ?   ?   B . n 
B 1 149 GLN 149 149 ?   ?   ?   B . n 
B 1 150 ASN 150 150 ?   ?   ?   B . n 
B 1 151 LEU 151 151 ?   ?   ?   B . n 
B 1 152 ASN 152 152 ?   ?   ?   B . n 
B 1 153 PHE 153 153 ?   ?   ?   B . n 
B 1 154 THR 154 154 ?   ?   ?   B . n 
B 1 155 GLY 155 155 ?   ?   ?   B . n 
B 1 156 PHE 156 156 ?   ?   ?   B . n 
B 1 157 ARG 157 157 ?   ?   ?   B . n 
B 1 158 LYS 158 158 ?   ?   ?   B . n 
B 1 159 ILE 159 159 ?   ?   ?   B . n 
B 1 160 LEU 160 160 ?   ?   ?   B . n 
B 1 161 LYS 161 161 ?   ?   ?   B . n 
B 1 162 LYS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 ASP 164 164 ?   ?   ?   B . n 
B 1 165 LYS 165 165 ?   ?   ?   B . n 
B 1 166 ILE 166 166 ?   ?   ?   B . n 
B 1 167 LEU 167 167 ?   ?   ?   B . n 
B 1 168 GLU 168 168 ?   ?   ?   B . n 
B 1 169 THR 169 169 ?   ?   ?   B . n 
B 1 170 SER 170 170 ?   ?   ?   B . n 
B 1 171 ARG 171 171 ?   ?   ?   B . n 
B 1 172 GLY 172 172 ?   ?   ?   B . n 
B 1 173 ALA 173 173 ?   ?   ?   B . n 
B 1 174 ASP 174 174 ?   ?   ?   B . n 
B 1 175 TRP 175 175 ?   ?   ?   B . n 
B 1 176 ARG 176 176 ?   ?   ?   B . n 
B 1 177 VAL 177 177 ?   ?   ?   B . n 
B 1 178 ALA 178 178 ?   ?   ?   B . n 
B 1 179 HIS 179 179 ?   ?   ?   B . n 
B 1 180 VAL 180 180 ?   ?   ?   B . n 
B 1 181 GLU 181 181 ?   ?   ?   B . n 
B 1 182 VAL 182 182 ?   ?   ?   B . n 
B 1 183 ALA 183 183 ?   ?   ?   B . n 
B 1 184 PRO 184 184 ?   ?   ?   B . n 
B 1 185 PHE 185 185 ?   ?   ?   B . n 
B 1 186 TYR 186 186 ?   ?   ?   B . n 
B 1 187 THR 187 187 ?   ?   ?   B . n 
B 1 188 CYS 188 188 ?   ?   ?   B . n 
B 1 189 LYS 189 189 ?   ?   ?   B . n 
B 1 190 LYS 190 190 ?   ?   ?   B . n 
B 1 191 ILE 191 191 ?   ?   ?   B . n 
B 1 192 ASN 192 192 ?   ?   ?   B . n 
B 1 193 GLN 193 193 ?   ?   ?   B . n 
B 1 194 LEU 194 194 ?   ?   ?   B . n 
B 1 195 ILE 195 195 ?   ?   ?   B . n 
B 1 196 SER 196 196 ?   ?   ?   B . n 
B 1 197 GLU 197 197 ?   ?   ?   B . n 
B 1 198 THR 198 198 ?   ?   ?   B . n 
B 1 199 GLU 199 199 ?   ?   ?   B . n 
B 1 200 ALA 200 200 ?   ?   ?   B . n 
B 1 201 VAL 201 201 ?   ?   ?   B . n 
B 1 202 VAL 202 202 ?   ?   ?   B . n 
B 1 203 THR 203 203 ?   ?   ?   B . n 
B 1 204 ASN 204 204 ?   ?   ?   B . n 
B 1 205 GLU 205 205 ?   ?   ?   B . n 
B 1 206 LEU 206 206 ?   ?   ?   B . n 
B 1 207 GLU 207 207 ?   ?   ?   B . n 
B 1 208 ASP 208 208 ?   ?   ?   B . n 
B 1 209 GLY 209 209 ?   ?   ?   B . n 
B 1 210 ASP 210 210 ?   ?   ?   B . n 
B 1 211 ARG 211 211 ?   ?   ?   B . n 
B 1 212 GLN 212 212 ?   ?   ?   B . n 
B 1 213 LYS 213 213 ?   ?   ?   B . n 
B 1 214 ALA 214 214 ?   ?   ?   B . n 
B 1 215 MET 215 215 ?   ?   ?   B . n 
B 1 216 LYS 216 216 ?   ?   ?   B . n 
B 1 217 ARG 217 217 ?   ?   ?   B . n 
B 1 218 LEU 218 218 ?   ?   ?   B . n 
B 1 219 ARG 219 219 ?   ?   ?   B . n 
B 1 220 VAL 220 220 ?   ?   ?   B . n 
B 1 221 PRO 221 221 ?   ?   ?   B . n 
B 1 222 PRO 222 222 ?   ?   ?   B . n 
B 1 223 LEU 223 223 ?   ?   ?   B . n 
B 1 224 GLY 224 224 ?   ?   ?   B . n 
B 1 225 ALA 225 225 ?   ?   ?   B . n 
B 1 226 ALA 226 226 ?   ?   ?   B . n 
B 1 227 GLN 227 227 ?   ?   ?   B . n 
B 1 228 PRO 228 228 ?   ?   ?   B . n 
B 1 229 ALA 229 229 229 ALA ALA B . n 
B 1 230 PRO 230 230 230 PRO PRO B . n 
B 1 231 ALA 231 231 231 ALA ALA B . n 
B 1 232 TRP 232 232 232 TRP TRP B . n 
B 1 233 THR 233 233 233 THR THR B . n 
B 1 234 THR 234 234 234 THR THR B . n 
B 1 235 PHE 235 235 235 PHE PHE B . n 
B 1 236 ARG 236 236 236 ARG ARG B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 PHE 240 240 240 PHE PHE B . n 
B 1 241 CYS 241 241 241 CYS CYS B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ILE 243 243 243 ILE ILE B . n 
B 1 244 PHE 244 244 244 PHE PHE B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 LEU 247 247 247 LEU LEU B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 THR 250 250 250 THR THR B . n 
B 1 251 LEU 251 251 251 LEU LEU B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 VAL 256 256 256 VAL VAL B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 LYS 258 258 258 LYS LYS B . n 
B 1 259 LEU 259 259 259 LEU LEU B . n 
B 1 260 GLU 260 260 260 GLU GLU B . n 
B 1 261 THR 261 261 261 THR THR B . n 
B 1 262 ASP 262 262 262 ASP ASP B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ILE 265 265 265 ILE ILE B . n 
B 1 266 TRP 266 266 266 TRP TRP B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 ARG 270 270 270 ARG ARG B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 TYR 272 272 272 TYR TYR B . n 
B 1 273 ARG 273 273 273 ARG ARG B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 PHE 276 276 276 PHE PHE B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 PHE 283 283 283 PHE PHE B . n 
B 1 284 LEU 284 284 284 LEU LEU B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 GLY 286 286 286 GLY GLY B . n 
B 1 287 ILE 287 287 287 ILE ILE B . n 
B 1 288 ASN 288 288 288 ASN ASN B . n 
B 1 289 THR 289 289 289 THR THR B . n 
B 1 290 TYR 290 290 290 TYR TYR B . n 
B 1 291 GLY 291 291 291 GLY GLY B . n 
B 1 292 TRP 292 292 292 TRP TRP B . n 
B 1 293 ARG 293 293 293 ARG ARG B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ASN 298 298 298 ASN ASN B . n 
B 1 299 HIS 299 299 299 HIS HIS B . n 
B 1 300 VAL 300 300 300 VAL VAL B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 LEU 305 305 305 LEU LEU B . n 
B 1 306 ASN 306 306 306 ASN ASN B . n 
B 1 307 PRO 307 307 307 PRO PRO B . n 
B 1 308 ARG 308 308 308 ARG ARG B . n 
B 1 309 SER 309 309 309 SER SER B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 LEU 311 311 311 LEU LEU B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 HIS 313 313 313 HIS HIS B . n 
B 1 314 GLN 314 314 314 GLN GLN B . n 
B 1 315 HIS 315 315 315 HIS HIS B . n 
B 1 316 LEU 316 316 316 LEU LEU B . n 
B 1 317 PHE 317 317 317 PHE PHE B . n 
B 1 318 GLU 318 318 318 GLU GLU B . n 
B 1 319 ILE 319 319 319 ILE ILE B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 PHE 322 322 322 PHE PHE B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 GLY 324 324 324 GLY GLY B . n 
B 1 325 ILE 325 325 325 ILE ILE B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 TRP 327 327 327 TRP TRP B . n 
B 1 328 CYS 328 328 328 CYS CYS B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 SER 330 330 330 SER SER B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 CYS 334 334 334 CYS CYS B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 PRO 338 338 338 PRO PRO B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 SER 340 340 340 SER SER B . n 
B 1 341 VAL 341 341 341 VAL VAL B . n 
B 1 342 ILE 342 342 342 ILE ILE B . n 
B 1 343 PRO 343 343 343 PRO PRO B . n 
B 1 344 THR 344 344 344 THR THR B . n 
B 1 345 TYR 345 345 345 TYR TYR B . n 
B 1 346 VAL 346 346 346 VAL VAL B . n 
B 1 347 TYR 347 347 347 TYR TYR B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 LEU 349 349 349 LEU LEU B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 TYR 352 352 352 TYR TYR B . n 
B 1 353 GLY 353 353 353 GLY GLY B . n 
B 1 354 PHE 354 354 354 PHE PHE B . n 
B 1 355 MET 355 355 355 MET MET B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PHE 357 357 357 PHE PHE B . n 
B 1 358 PHE 358 358 358 PHE PHE B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 ASN 361 361 361 ASN ASN B . n 
B 1 362 PRO 362 362 362 PRO PRO B . n 
B 1 363 THR 363 363 363 THR THR B . n 
B 1 364 LYS 364 364 364 LYS LYS B . n 
B 1 365 THR 365 365 365 THR THR B . n 
B 1 366 PHE 366 366 366 PHE PHE B . n 
B 1 367 TYR 367 367 367 TYR TYR B . n 
B 1 368 TYR 368 368 368 TYR TYR B . n 
B 1 369 LYS 369 369 369 LYS LYS B . n 
B 1 370 SER 370 370 370 SER SER B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 TRP 373 373 373 TRP TRP B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 LYS 376 376 376 LYS LYS B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 PHE 379 379 379 PHE PHE B . n 
B 1 380 ARG 380 380 380 ARG ARG B . n 
B 1 381 VAL 381 381 381 VAL VAL B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 THR 383 383 383 THR THR B . n 
B 1 384 ALA 384 384 384 ALA ALA B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 PHE 386 386 386 PHE PHE B . n 
B 1 387 HIS 387 387 387 HIS HIS B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 VAL 389 389 389 VAL VAL B . n 
B 1 390 GLY 390 390 390 GLY GLY B . n 
B 1 391 PHE 391 391 391 PHE PHE B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 ASP 393 393 393 ASP ASP B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 TRP 395 395 395 TRP TRP B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 ALA 397 397 397 ALA ALA B . n 
B 1 398 ASP 398 398 398 ASP ASP B . n 
B 1 399 GLN 399 399 399 GLN GLN B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 ASN 401 401 401 ASN ASN B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 VAL 405 405 405 VAL VAL B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 LEU 407 407 407 LEU LEU B . n 
B 1 408 MET 408 408 408 MET MET B . n 
B 1 409 ASP 409 409 409 ASP ASP B . n 
B 1 410 LEU 410 410 410 LEU LEU B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 MET 413 413 413 MET MET B . n 
B 1 414 ILE 414 414 414 ILE ILE B . n 
B 1 415 CYS 415 415 415 CYS CYS B . n 
B 1 416 PHE 416 416 416 PHE PHE B . n 
B 1 417 TYR 417 417 417 TYR TYR B . n 
B 1 418 SER 418 418 418 SER SER B . n 
B 1 419 LEU 419 419 419 LEU LEU B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 LYS 422 422 422 LYS LYS B . n 
B 1 423 TRP 423 423 423 TRP TRP B . n 
B 1 424 ASP 424 424 424 ASP ASP B . n 
B 1 425 GLU 425 425 425 GLU GLU B . n 
B 1 426 SER 426 426 426 SER SER B . n 
B 1 427 LYS 427 427 427 LYS LYS B . n 
B 1 428 GLY 428 428 428 GLY GLY B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 PRO 431 431 431 PRO PRO B . n 
B 1 432 ASN 432 432 ?   ?   ?   B . n 
B 1 433 ASN 433 433 ?   ?   ?   B . n 
B 1 434 SER 434 434 ?   ?   ?   B . n 
B 1 435 GLU 435 435 ?   ?   ?   B . n 
B 1 436 GLU 436 436 ?   ?   ?   B . n 
B 1 437 SER 437 437 ?   ?   ?   B . n 
B 1 438 GLY 438 438 ?   ?   ?   B . n 
B 1 439 ILE 439 439 ?   ?   ?   B . n 
B 1 440 CYS 440 440 ?   ?   ?   B . n 
B 1 441 HIS 441 441 ?   ?   ?   B . n 
B 1 442 LYS 442 442 ?   ?   ?   B . n 
B 1 443 TYR 443 443 ?   ?   ?   B . n 
B 1 444 THR 444 444 ?   ?   ?   B . n 
B 1 445 TYR 445 445 ?   ?   ?   B . n 
B 1 446 GLY 446 446 446 GLY GLY B . n 
B 1 447 VAL 447 447 447 VAL VAL B . n 
B 1 448 ARG 448 448 448 ARG ARG B . n 
B 1 449 ALA 449 449 449 ALA ALA B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 VAL 451 451 451 VAL VAL B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 CYS 453 453 453 CYS CYS B . n 
B 1 454 ILE 454 454 454 ILE ILE B . n 
B 1 455 PRO 455 455 455 PRO PRO B . n 
B 1 456 ALA 456 456 456 ALA ALA B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 LEU 458 458 458 LEU LEU B . n 
B 1 459 ARG 459 459 459 ARG ARG B . n 
B 1 460 PHE 460 460 460 PHE PHE B . n 
B 1 461 ILE 461 461 461 ILE ILE B . n 
B 1 462 GLN 462 462 462 GLN GLN B . n 
B 1 463 CYS 463 463 463 CYS CYS B . n 
B 1 464 LEU 464 464 464 LEU LEU B . n 
B 1 465 ARG 465 465 465 ARG ARG B . n 
B 1 466 ARG 466 466 466 ARG ARG B . n 
B 1 467 TYR 467 467 467 TYR TYR B . n 
B 1 468 ARG 468 468 468 ARG ARG B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 LYS 471 471 471 LYS LYS B . n 
B 1 472 ARG 472 472 472 ARG ARG B . n 
B 1 473 ALA 473 473 473 ALA ALA B . n 
B 1 474 PHE 474 474 474 PHE PHE B . n 
B 1 475 PRO 475 475 475 PRO PRO B . n 
B 1 476 HIS 476 476 476 HIS HIS B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 VAL 478 478 478 VAL VAL B . n 
B 1 479 ASN 479 479 479 ASN ASN B . n 
B 1 480 ALA 480 480 480 ALA ALA B . n 
B 1 481 GLY 481 481 481 GLY GLY B . n 
B 1 482 LYS 482 482 482 LYS LYS B . n 
B 1 483 TYR 483 483 483 TYR TYR B . n 
B 1 484 SER 484 484 484 SER SER B . n 
B 1 485 THR 485 485 485 THR THR B . n 
B 1 486 THR 486 486 486 THR THR B . n 
B 1 487 PHE 487 487 487 PHE PHE B . n 
B 1 488 PHE 488 488 488 PHE PHE B . n 
B 1 489 MET 489 489 489 MET MET B . n 
B 1 490 VAL 490 490 490 VAL VAL B . n 
B 1 491 THR 491 491 491 THR THR B . n 
B 1 492 PHE 492 492 492 PHE PHE B . n 
B 1 493 ALA 493 493 493 ALA ALA B . n 
B 1 494 ALA 494 494 494 ALA ALA B . n 
B 1 495 LEU 495 495 495 LEU LEU B . n 
B 1 496 TYR 496 496 496 TYR TYR B . n 
B 1 497 SER 497 497 497 SER SER B . n 
B 1 498 THR 498 498 498 THR THR B . n 
B 1 499 HIS 499 499 499 HIS HIS B . n 
B 1 500 LYS 500 500 500 LYS LYS B . n 
B 1 501 GLU 501 501 501 GLU GLU B . n 
B 1 502 ARG 502 502 502 ARG ARG B . n 
B 1 503 GLY 503 503 503 GLY GLY B . n 
B 1 504 HIS 504 504 504 HIS HIS B . n 
B 1 505 SER 505 505 505 SER SER B . n 
B 1 506 ASP 506 506 506 ASP ASP B . n 
B 1 507 THR 507 507 507 THR THR B . n 
B 1 508 MET 508 508 508 MET MET B . n 
B 1 509 VAL 509 509 509 VAL VAL B . n 
B 1 510 PHE 510 510 510 PHE PHE B . n 
B 1 511 PHE 511 511 511 PHE PHE B . n 
B 1 512 TYR 512 512 512 TYR TYR B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TRP 514 514 514 TRP TRP B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 VAL 516 516 516 VAL VAL B . n 
B 1 517 PHE 517 517 517 PHE PHE B . n 
B 1 518 TYR 518 518 518 TYR TYR B . n 
B 1 519 ILE 519 519 519 ILE ILE B . n 
B 1 520 ILE 520 520 520 ILE ILE B . n 
B 1 521 SER 521 521 521 SER SER B . n 
B 1 522 SER 522 522 522 SER SER B . n 
B 1 523 CYS 523 523 523 CYS CYS B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 THR 525 525 525 THR THR B . n 
B 1 526 LEU 526 526 526 LEU LEU B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 TRP 528 528 528 TRP TRP B . n 
B 1 529 ASP 529 529 529 ASP ASP B . n 
B 1 530 LEU 530 530 530 LEU LEU B . n 
B 1 531 LYS 531 531 531 LYS LYS B . n 
B 1 532 MET 532 532 532 MET MET B . n 
B 1 533 ASP 533 533 533 ASP ASP B . n 
B 1 534 TRP 534 534 534 TRP TRP B . n 
B 1 535 GLY 535 535 535 GLY GLY B . n 
B 1 536 LEU 536 536 536 LEU LEU B . n 
B 1 537 PHE 537 537 537 PHE PHE B . n 
B 1 538 ASP 538 538 538 ASP ASP B . n 
B 1 539 LYS 539 539 539 LYS LYS B . n 
B 1 540 ASN 540 540 540 ASN ASN B . n 
B 1 541 ALA 541 541 541 ALA ALA B . n 
B 1 542 GLY 542 542 542 GLY GLY B . n 
B 1 543 GLU 543 543 543 GLU GLU B . n 
B 1 544 ASN 544 544 544 ASN ASN B . n 
B 1 545 THR 545 545 545 THR THR B . n 
B 1 546 PHE 546 546 546 PHE PHE B . n 
B 1 547 LEU 547 547 547 LEU LEU B . n 
B 1 548 ARG 548 548 548 ARG ARG B . n 
B 1 549 GLU 549 549 549 GLU GLU B . n 
B 1 550 GLU 550 550 550 GLU GLU B . n 
B 1 551 ILE 551 551 551 ILE ILE B . n 
B 1 552 VAL 552 552 552 VAL VAL B . n 
B 1 553 TYR 553 553 553 TYR TYR B . n 
B 1 554 PRO 554 554 554 PRO PRO B . n 
B 1 555 GLN 555 555 555 GLN GLN B . n 
B 1 556 LYS 556 556 556 LYS LYS B . n 
B 1 557 ALA 557 557 557 ALA ALA B . n 
B 1 558 TYR 558 558 558 TYR TYR B . n 
B 1 559 TYR 559 559 559 TYR TYR B . n 
B 1 560 TYR 560 560 560 TYR TYR B . n 
B 1 561 CYS 561 561 561 CYS CYS B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 ILE 563 563 563 ILE ILE B . n 
B 1 564 ILE 564 564 564 ILE ILE B . n 
B 1 565 GLU 565 565 565 GLU GLU B . n 
B 1 566 ASP 566 566 566 ASP ASP B . n 
B 1 567 VAL 567 567 567 VAL VAL B . n 
B 1 568 ILE 568 568 568 ILE ILE B . n 
B 1 569 LEU 569 569 569 LEU LEU B . n 
B 1 570 ARG 570 570 570 ARG ARG B . n 
B 1 571 PHE 571 571 571 PHE PHE B . n 
B 1 572 ALA 572 572 572 ALA ALA B . n 
B 1 573 TRP 573 573 573 TRP TRP B . n 
B 1 574 THR 574 574 574 THR THR B . n 
B 1 575 ILE 575 575 575 ILE ILE B . n 
B 1 576 GLN 576 576 576 GLN GLN B . n 
B 1 577 ILE 577 577 577 ILE ILE B . n 
B 1 578 SER 578 578 578 SER SER B . n 
B 1 579 ILE 579 579 579 ILE ILE B . n 
B 1 580 THR 580 580 580 THR THR B . n 
B 1 581 SER 581 581 581 SER SER B . n 
B 1 582 THR 582 582 582 THR THR B . n 
B 1 583 THR 583 583 583 THR THR B . n 
B 1 584 LEU 584 584 584 LEU LEU B . n 
B 1 585 LEU 585 585 585 LEU LEU B . n 
B 1 586 PRO 586 586 586 PRO PRO B . n 
B 1 587 HIS 587 587 587 HIS HIS B . n 
B 1 588 SER 588 588 588 SER SER B . n 
B 1 589 GLY 589 589 589 GLY GLY B . n 
B 1 590 ASP 590 590 590 ASP ASP B . n 
B 1 591 ILE 591 591 591 ILE ILE B . n 
B 1 592 ILE 592 592 592 ILE ILE B . n 
B 1 593 ALA 593 593 593 ALA ALA B . n 
B 1 594 THR 594 594 594 THR THR B . n 
B 1 595 VAL 595 595 595 VAL VAL B . n 
B 1 596 PHE 596 596 596 PHE PHE B . n 
B 1 597 ALA 597 597 597 ALA ALA B . n 
B 1 598 PRO 598 598 598 PRO PRO B . n 
B 1 599 LEU 599 599 599 LEU LEU B . n 
B 1 600 GLU 600 600 600 GLU GLU B . n 
B 1 601 VAL 601 601 601 VAL VAL B . n 
B 1 602 PHE 602 602 602 PHE PHE B . n 
B 1 603 ARG 603 603 603 ARG ARG B . n 
B 1 604 ARG 604 604 604 ARG ARG B . n 
B 1 605 PHE 605 605 605 PHE PHE B . n 
B 1 606 VAL 606 606 606 VAL VAL B . n 
B 1 607 TRP 607 607 607 TRP TRP B . n 
B 1 608 ASN 608 608 608 ASN ASN B . n 
B 1 609 PHE 609 609 609 PHE PHE B . n 
B 1 610 PHE 610 610 610 PHE PHE B . n 
B 1 611 ARG 611 611 611 ARG ARG B . n 
B 1 612 LEU 612 612 612 LEU LEU B . n 
B 1 613 GLU 613 613 613 GLU GLU B . n 
B 1 614 ASN 614 614 614 ASN ASN B . n 
B 1 615 GLU 615 615 615 GLU GLU B . n 
B 1 616 HIS 616 616 616 HIS HIS B . n 
B 1 617 LEU 617 617 617 LEU LEU B . n 
B 1 618 ASN 618 618 618 ASN ASN B . n 
B 1 619 ASN 619 619 619 ASN ASN B . n 
B 1 620 CYS 620 620 620 CYS CYS B . n 
B 1 621 GLY 621 621 621 GLY GLY B . n 
B 1 622 GLU 622 622 622 GLU GLU B . n 
B 1 623 PHE 623 623 623 PHE PHE B . n 
B 1 624 ARG 624 624 624 ARG ARG B . n 
B 1 625 ALA 625 625 ?   ?   ?   B . n 
B 1 626 VAL 626 626 ?   ?   ?   B . n 
B 1 627 ARG 627 627 ?   ?   ?   B . n 
B 1 628 ASP 628 628 ?   ?   ?   B . n 
B 1 629 ILE 629 629 ?   ?   ?   B . n 
B 1 630 SER 630 630 ?   ?   ?   B . n 
B 1 631 VAL 631 631 ?   ?   ?   B . n 
B 1 632 ALA 632 632 ?   ?   ?   B . n 
B 1 633 PRO 633 633 ?   ?   ?   B . n 
B 1 634 LEU 634 634 ?   ?   ?   B . n 
B 1 635 ASN 635 635 ?   ?   ?   B . n 
B 1 636 ALA 636 636 ?   ?   ?   B . n 
B 1 637 ASP 637 637 ?   ?   ?   B . n 
B 1 638 ASP 638 638 ?   ?   ?   B . n 
B 1 639 GLN 639 639 ?   ?   ?   B . n 
B 1 640 THR 640 640 ?   ?   ?   B . n 
B 1 641 LEU 641 641 ?   ?   ?   B . n 
B 1 642 LEU 642 642 ?   ?   ?   B . n 
B 1 643 GLU 643 643 ?   ?   ?   B . n 
B 1 644 GLN 644 644 ?   ?   ?   B . n 
B 1 645 MET 645 645 ?   ?   ?   B . n 
B 1 646 MET 646 646 ?   ?   ?   B . n 
B 1 647 ASP 647 647 ?   ?   ?   B . n 
B 1 648 GLN 648 648 ?   ?   ?   B . n 
B 1 649 ASP 649 649 ?   ?   ?   B . n 
B 1 650 ASP 650 650 ?   ?   ?   B . n 
B 1 651 GLY 651 651 ?   ?   ?   B . n 
B 1 652 VAL 652 652 ?   ?   ?   B . n 
B 1 653 ARG 653 653 ?   ?   ?   B . n 
B 1 654 ASN 654 654 ?   ?   ?   B . n 
B 1 655 ARG 655 655 ?   ?   ?   B . n 
B 1 656 GLN 656 656 ?   ?   ?   B . n 
B 1 657 LYS 657 657 ?   ?   ?   B . n 
B 1 658 ASN 658 658 ?   ?   ?   B . n 
B 1 659 ARG 659 659 ?   ?   ?   B . n 
B 1 660 SER 660 660 ?   ?   ?   B . n 
B 1 661 TRP 661 661 ?   ?   ?   B . n 
B 1 662 LYS 662 662 ?   ?   ?   B . n 
B 1 663 TYR 663 663 ?   ?   ?   B . n 
B 1 664 ASN 664 664 ?   ?   ?   B . n 
B 1 665 GLN 665 665 ?   ?   ?   B . n 
B 1 666 SER 666 666 ?   ?   ?   B . n 
B 1 667 ILE 667 667 ?   ?   ?   B . n 
B 1 668 SER 668 668 ?   ?   ?   B . n 
B 1 669 LEU 669 669 ?   ?   ?   B . n 
B 1 670 ARG 670 670 ?   ?   ?   B . n 
B 1 671 ARG 671 671 ?   ?   ?   B . n 
B 1 672 PRO 672 672 ?   ?   ?   B . n 
B 1 673 ARG 673 673 ?   ?   ?   B . n 
B 1 674 LEU 674 674 ?   ?   ?   B . n 
B 1 675 ALA 675 675 ?   ?   ?   B . n 
B 1 676 SER 676 676 ?   ?   ?   B . n 
B 1 677 GLN 677 677 ?   ?   ?   B . n 
B 1 678 SER 678 678 ?   ?   ?   B . n 
B 1 679 LYS 679 679 ?   ?   ?   B . n 
B 1 680 ALA 680 680 ?   ?   ?   B . n 
B 1 681 ARG 681 681 ?   ?   ?   B . n 
B 1 682 ASP 682 682 ?   ?   ?   B . n 
B 1 683 THR 683 683 ?   ?   ?   B . n 
B 1 684 LYS 684 684 ?   ?   ?   B . n 
B 1 685 VAL 685 685 ?   ?   ?   B . n 
B 1 686 LEU 686 686 ?   ?   ?   B . n 
B 1 687 ILE 687 687 ?   ?   ?   B . n 
B 1 688 GLU 688 688 ?   ?   ?   B . n 
B 1 689 ASP 689 689 ?   ?   ?   B . n 
B 1 690 THR 690 690 ?   ?   ?   B . n 
B 1 691 ASP 691 691 ?   ?   ?   B . n 
B 1 692 ASP 692 692 ?   ?   ?   B . n 
B 1 693 GLU 693 693 ?   ?   ?   B . n 
B 1 694 ALA 694 694 ?   ?   ?   B . n 
B 1 695 ASN 695 695 ?   ?   ?   B . n 
B 1 696 THR 696 696 ?   ?   ?   B . n 
B 1 697 LEU 697 697 ?   ?   ?   B . n 
B 1 698 GLU 698 698 ?   ?   ?   B . n 
B 1 699 ASP 699 699 ?   ?   ?   B . n 
B 1 700 TYR 700 700 ?   ?   ?   B . n 
B 1 701 LYS 701 701 ?   ?   ?   B . n 
B 1 702 ASP 702 702 ?   ?   ?   B . n 
B 1 703 HIS 703 703 ?   ?   ?   B . n 
B 1 704 ASP 704 704 ?   ?   ?   B . n 
B 1 705 GLY 705 705 ?   ?   ?   B . n 
B 1 706 ASP 706 706 ?   ?   ?   B . n 
B 1 707 TYR 707 707 ?   ?   ?   B . n 
B 1 708 LYS 708 708 ?   ?   ?   B . n 
B 1 709 ASP 709 709 ?   ?   ?   B . n 
B 1 710 HIS 710 710 ?   ?   ?   B . n 
B 1 711 ASP 711 711 ?   ?   ?   B . n 
B 1 712 ILE 712 712 ?   ?   ?   B . n 
B 1 713 ASP 713 713 ?   ?   ?   B . n 
B 1 714 TYR 714 714 ?   ?   ?   B . n 
B 1 715 LYS 715 715 ?   ?   ?   B . n 
B 1 716 ASP 716 716 ?   ?   ?   B . n 
B 1 717 ASP 717 717 ?   ?   ?   B . n 
B 1 718 ASP 718 718 ?   ?   ?   B . n 
B 1 719 ASP 719 719 ?   ?   ?   B . n 
B 1 720 LYS 720 720 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 PC1 1 801 702 PC1 PC1 A . 
D 2 PC1 1 802 703 PC1 PC1 A . 
E 3 PO4 1 803 7   PO4 PO4 A . 
F 2 PC1 1 801 702 PC1 PC1 B . 
G 2 PC1 1 802 703 PC1 PC1 B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9J52 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9J52 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9J52 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9J52 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 6802 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.516  ? 9212 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 12.891 ? 2468 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.038  ? 986  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 1100 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9J52 
_struct.title                        'CryoEM structure of human XPR1 in complex with phosphate in state B' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9J52 
_struct_keywords.text            'Phosphate, Transport, XPR1, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S53A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9UBH6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9J52 A 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
2 1 9J52 B 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9J52 LEU A 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 1  
1 9J52 GLU A 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 2  
1 9J52 ASP A 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 3  
1 9J52 TYR A 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 4  
1 9J52 LYS A 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 5  
1 9J52 ASP A 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 6  
1 9J52 HIS A 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 7  
1 9J52 ASP A 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 8  
1 9J52 GLY A 705 ? UNP Q9UBH6 ? ? 'expression tag' 705 9  
1 9J52 ASP A 706 ? UNP Q9UBH6 ? ? 'expression tag' 706 10 
1 9J52 TYR A 707 ? UNP Q9UBH6 ? ? 'expression tag' 707 11 
1 9J52 LYS A 708 ? UNP Q9UBH6 ? ? 'expression tag' 708 12 
1 9J52 ASP A 709 ? UNP Q9UBH6 ? ? 'expression tag' 709 13 
1 9J52 HIS A 710 ? UNP Q9UBH6 ? ? 'expression tag' 710 14 
1 9J52 ASP A 711 ? UNP Q9UBH6 ? ? 'expression tag' 711 15 
1 9J52 ILE A 712 ? UNP Q9UBH6 ? ? 'expression tag' 712 16 
1 9J52 ASP A 713 ? UNP Q9UBH6 ? ? 'expression tag' 713 17 
1 9J52 TYR A 714 ? UNP Q9UBH6 ? ? 'expression tag' 714 18 
1 9J52 LYS A 715 ? UNP Q9UBH6 ? ? 'expression tag' 715 19 
1 9J52 ASP A 716 ? UNP Q9UBH6 ? ? 'expression tag' 716 20 
1 9J52 ASP A 717 ? UNP Q9UBH6 ? ? 'expression tag' 717 21 
1 9J52 ASP A 718 ? UNP Q9UBH6 ? ? 'expression tag' 718 22 
1 9J52 ASP A 719 ? UNP Q9UBH6 ? ? 'expression tag' 719 23 
1 9J52 LYS A 720 ? UNP Q9UBH6 ? ? 'expression tag' 720 24 
2 9J52 LEU B 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 25 
2 9J52 GLU B 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 26 
2 9J52 ASP B 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 27 
2 9J52 TYR B 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 28 
2 9J52 LYS B 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 29 
2 9J52 ASP B 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 30 
2 9J52 HIS B 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 31 
2 9J52 ASP B 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 32 
2 9J52 GLY B 705 ? UNP Q9UBH6 ? ? 'expression tag' 705 33 
2 9J52 ASP B 706 ? UNP Q9UBH6 ? ? 'expression tag' 706 34 
2 9J52 TYR B 707 ? UNP Q9UBH6 ? ? 'expression tag' 707 35 
2 9J52 LYS B 708 ? UNP Q9UBH6 ? ? 'expression tag' 708 36 
2 9J52 ASP B 709 ? UNP Q9UBH6 ? ? 'expression tag' 709 37 
2 9J52 HIS B 710 ? UNP Q9UBH6 ? ? 'expression tag' 710 38 
2 9J52 ASP B 711 ? UNP Q9UBH6 ? ? 'expression tag' 711 39 
2 9J52 ILE B 712 ? UNP Q9UBH6 ? ? 'expression tag' 712 40 
2 9J52 ASP B 713 ? UNP Q9UBH6 ? ? 'expression tag' 713 41 
2 9J52 TYR B 714 ? UNP Q9UBH6 ? ? 'expression tag' 714 42 
2 9J52 LYS B 715 ? UNP Q9UBH6 ? ? 'expression tag' 715 43 
2 9J52 ASP B 716 ? UNP Q9UBH6 ? ? 'expression tag' 716 44 
2 9J52 ASP B 717 ? UNP Q9UBH6 ? ? 'expression tag' 717 45 
2 9J52 ASP B 718 ? UNP Q9UBH6 ? ? 'expression tag' 718 46 
2 9J52 ASP B 719 ? UNP Q9UBH6 ? ? 'expression tag' 719 47 
2 9J52 LYS B 720 ? UNP Q9UBH6 ? ? 'expression tag' 720 48 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 230 ? LYS A 258 ? PRO A 230 LYS A 258 1 ? 29 
HELX_P HELX_P2  AA2 ILE A 265 ? ALA A 295 ? ILE A 265 ALA A 295 1 ? 31 
HELX_P HELX_P3  AA3 ASN A 298 ? PHE A 303 ? ASN A 298 PHE A 303 1 ? 6  
HELX_P HELX_P4  AA4 SER A 312 ? PHE A 336 ? SER A 312 PHE A 336 1 ? 25 
HELX_P HELX_P5  AA5 ALA A 337 ? SER A 340 ? ALA A 337 SER A 340 5 ? 4  
HELX_P HELX_P6  AA6 PRO A 343 ? TYR A 345 ? PRO A 343 TYR A 345 5 ? 3  
HELX_P HELX_P7  AA7 VAL A 346 ? ILE A 360 ? VAL A 346 ILE A 360 1 ? 15 
HELX_P HELX_P8  AA8 TYR A 367 ? ALA A 384 ? TYR A 367 ALA A 384 1 ? 18 
HELX_P HELX_P9  AA9 GLY A 390 ? SER A 402 ? GLY A 390 SER A 402 1 ? 13 
HELX_P HELX_P10 AB1 LEU A 403 ? GLU A 420 ? LEU A 403 GLU A 420 1 ? 18 
HELX_P HELX_P11 AB2 VAL A 447 ? CYS A 453 ? VAL A 447 CYS A 453 1 ? 7  
HELX_P HELX_P12 AB3 CYS A 453 ? LYS A 471 ? CYS A 453 LYS A 471 1 ? 19 
HELX_P HELX_P13 AB4 ARG A 472 ? GLY A 503 ? ARG A 472 GLY A 503 1 ? 32 
HELX_P HELX_P14 AB5 SER A 505 ? MET A 532 ? SER A 505 MET A 532 1 ? 28 
HELX_P HELX_P15 AB6 LYS A 556 ? THR A 583 ? LYS A 556 THR A 583 1 ? 28 
HELX_P HELX_P16 AB7 GLY A 589 ? ASN A 618 ? GLY A 589 ASN A 618 1 ? 30 
HELX_P HELX_P17 AB8 PRO B 230 ? LYS B 258 ? PRO B 230 LYS B 258 1 ? 29 
HELX_P HELX_P18 AB9 ILE B 265 ? GLY B 296 ? ILE B 265 GLY B 296 1 ? 32 
HELX_P HELX_P19 AC1 ASN B 298 ? PHE B 303 ? ASN B 298 PHE B 303 1 ? 6  
HELX_P HELX_P20 AC2 SER B 312 ? ALA B 337 ? SER B 312 ALA B 337 1 ? 26 
HELX_P HELX_P21 AC3 TYR B 345 ? ASN B 361 ? TYR B 345 ASN B 361 1 ? 17 
HELX_P HELX_P22 AC4 TYR B 367 ? THR B 383 ? TYR B 367 THR B 383 1 ? 17 
HELX_P HELX_P23 AC5 ALA B 384 ? HIS B 387 ? ALA B 384 HIS B 387 5 ? 4  
HELX_P HELX_P24 AC6 GLY B 390 ? LEU B 419 ? GLY B 390 LEU B 419 1 ? 30 
HELX_P HELX_P25 AC7 VAL B 447 ? CYS B 453 ? VAL B 447 CYS B 453 1 ? 7  
HELX_P HELX_P26 AC8 CYS B 453 ? GLN B 462 ? CYS B 453 GLN B 462 1 ? 10 
HELX_P HELX_P27 AC9 LEU B 464 ? LYS B 471 ? LEU B 464 LYS B 471 1 ? 8  
HELX_P HELX_P28 AD1 ARG B 472 ? GLY B 503 ? ARG B 472 GLY B 503 1 ? 32 
HELX_P HELX_P29 AD2 THR B 507 ? MET B 532 ? THR B 507 MET B 532 1 ? 26 
HELX_P HELX_P30 AD3 GLN B 555 ? THR B 580 ? GLN B 555 THR B 580 1 ? 26 
HELX_P HELX_P31 AD4 GLY B 589 ? ASN B 618 ? GLY B 589 ASN B 618 1 ? 30 
HELX_P HELX_P32 AD5 ASN B 619 ? PHE B 623 ? ASN B 619 PHE B 623 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9J52 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O B ILE 271 ? ? OH  B TYR 352 ? ? 2.10 
2 1 O B LYS 482 ? ? OG1 B THR 485 ? ? 2.15 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 338 ? ? -53.46  -3.91   
2  1 THR A 383 ? ? -64.81  -71.76  
3  1 PRO A 385 ? ? -75.96  45.70   
4  1 GLU A 420 ? ? -118.16 -169.40 
5  1 TRP A 423 ? ? 73.36   -6.74   
6  1 LEU A 430 ? ? 67.41   145.39  
7  1 LEU A 547 ? ? -129.31 -169.61 
8  1 LEU A 617 ? ? -94.02  -60.24  
9  1 LEU B 259 ? ? 61.83   67.67   
10 1 ILE B 265 ? ? 67.89   -59.52  
11 1 SER B 309 ? ? 56.18   -104.78 
12 1 ALA B 337 ? ? 53.09   73.58   
13 1 VAL B 341 ? ? -124.75 -53.46  
14 1 PHE B 366 ? ? 61.61   60.29   
15 1 LEU B 421 ? ? 54.42   -140.57 
16 1 LYS B 427 ? ? 61.35   -174.08 
17 1 LEU B 429 ? ? 63.08   -176.30 
18 1 VAL B 447 ? ? 57.83   -75.30  
19 1 CYS B 463 ? ? 71.35   -10.00  
20 1 SER B 505 ? ? 68.79   -4.03   
21 1 THR B 507 ? ? 42.12   -107.17 
22 1 ARG B 548 ? ? 178.66  176.43  
23 1 LEU B 584 ? ? 52.54   -127.75 
24 1 SER B 588 ? ? 54.18   -98.52  
25 1 ASN B 619 ? ? -68.44  91.74   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9J52 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9J52 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               141213 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human XPR1' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9J52 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9J52 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9J52 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9J52 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A LYS 2   ? A LYS 2   
3   1 Y 1 A PHE 3   ? A PHE 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A GLU 5   ? A GLU 5   
6   1 Y 1 A HIS 6   ? A HIS 6   
7   1 Y 1 A LEU 7   ? A LEU 7   
8   1 Y 1 A SER 8   ? A SER 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A HIS 10  ? A HIS 10  
11  1 Y 1 A ILE 11  ? A ILE 11  
12  1 Y 1 A THR 12  ? A THR 12  
13  1 Y 1 A PRO 13  ? A PRO 13  
14  1 Y 1 A GLU 14  ? A GLU 14  
15  1 Y 1 A TRP 15  ? A TRP 15  
16  1 Y 1 A ARG 16  ? A ARG 16  
17  1 Y 1 A LYS 17  ? A LYS 17  
18  1 Y 1 A GLN 18  ? A GLN 18  
19  1 Y 1 A TYR 19  ? A TYR 19  
20  1 Y 1 A ILE 20  ? A ILE 20  
21  1 Y 1 A GLN 21  ? A GLN 21  
22  1 Y 1 A TYR 22  ? A TYR 22  
23  1 Y 1 A GLU 23  ? A GLU 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A PHE 25  ? A PHE 25  
26  1 Y 1 A LYS 26  ? A LYS 26  
27  1 Y 1 A ASP 27  ? A ASP 27  
28  1 Y 1 A MET 28  ? A MET 28  
29  1 Y 1 A LEU 29  ? A LEU 29  
30  1 Y 1 A TYR 30  ? A TYR 30  
31  1 Y 1 A SER 31  ? A SER 31  
32  1 Y 1 A ALA 32  ? A ALA 32  
33  1 Y 1 A GLN 33  ? A GLN 33  
34  1 Y 1 A ASP 34  ? A ASP 34  
35  1 Y 1 A GLN 35  ? A GLN 35  
36  1 Y 1 A ALA 36  ? A ALA 36  
37  1 Y 1 A PRO 37  ? A PRO 37  
38  1 Y 1 A SER 38  ? A SER 38  
39  1 Y 1 A VAL 39  ? A VAL 39  
40  1 Y 1 A GLU 40  ? A GLU 40  
41  1 Y 1 A VAL 41  ? A VAL 41  
42  1 Y 1 A THR 42  ? A THR 42  
43  1 Y 1 A ASP 43  ? A ASP 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A ASP 45  ? A ASP 45  
46  1 Y 1 A THR 46  ? A THR 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A LYS 48  ? A LYS 48  
49  1 Y 1 A ARG 49  ? A ARG 49  
50  1 Y 1 A TYR 50  ? A TYR 50  
51  1 Y 1 A PHE 51  ? A PHE 51  
52  1 Y 1 A ALA 52  ? A ALA 52  
53  1 Y 1 A LYS 53  ? A LYS 53  
54  1 Y 1 A PHE 54  ? A PHE 54  
55  1 Y 1 A GLU 55  ? A GLU 55  
56  1 Y 1 A GLU 56  ? A GLU 56  
57  1 Y 1 A LYS 57  ? A LYS 57  
58  1 Y 1 A PHE 58  ? A PHE 58  
59  1 Y 1 A PHE 59  ? A PHE 59  
60  1 Y 1 A GLN 60  ? A GLN 60  
61  1 Y 1 A THR 61  ? A THR 61  
62  1 Y 1 A CYS 62  ? A CYS 62  
63  1 Y 1 A GLU 63  ? A GLU 63  
64  1 Y 1 A LYS 64  ? A LYS 64  
65  1 Y 1 A GLU 65  ? A GLU 65  
66  1 Y 1 A LEU 66  ? A LEU 66  
67  1 Y 1 A ALA 67  ? A ALA 67  
68  1 Y 1 A LYS 68  ? A LYS 68  
69  1 Y 1 A ILE 69  ? A ILE 69  
70  1 Y 1 A ASN 70  ? A ASN 70  
71  1 Y 1 A THR 71  ? A THR 71  
72  1 Y 1 A PHE 72  ? A PHE 72  
73  1 Y 1 A TYR 73  ? A TYR 73  
74  1 Y 1 A SER 74  ? A SER 74  
75  1 Y 1 A GLU 75  ? A GLU 75  
76  1 Y 1 A LYS 76  ? A LYS 76  
77  1 Y 1 A LEU 77  ? A LEU 77  
78  1 Y 1 A ALA 78  ? A ALA 78  
79  1 Y 1 A GLU 79  ? A GLU 79  
80  1 Y 1 A ALA 80  ? A ALA 80  
81  1 Y 1 A GLN 81  ? A GLN 81  
82  1 Y 1 A ARG 82  ? A ARG 82  
83  1 Y 1 A ARG 83  ? A ARG 83  
84  1 Y 1 A PHE 84  ? A PHE 84  
85  1 Y 1 A ALA 85  ? A ALA 85  
86  1 Y 1 A THR 86  ? A THR 86  
87  1 Y 1 A LEU 87  ? A LEU 87  
88  1 Y 1 A GLN 88  ? A GLN 88  
89  1 Y 1 A ASN 89  ? A ASN 89  
90  1 Y 1 A GLU 90  ? A GLU 90  
91  1 Y 1 A LEU 91  ? A LEU 91  
92  1 Y 1 A GLN 92  ? A GLN 92  
93  1 Y 1 A SER 93  ? A SER 93  
94  1 Y 1 A SER 94  ? A SER 94  
95  1 Y 1 A LEU 95  ? A LEU 95  
96  1 Y 1 A ASP 96  ? A ASP 96  
97  1 Y 1 A ALA 97  ? A ALA 97  
98  1 Y 1 A GLN 98  ? A GLN 98  
99  1 Y 1 A LYS 99  ? A LYS 99  
100 1 Y 1 A GLU 100 ? A GLU 100 
101 1 Y 1 A SER 101 ? A SER 101 
102 1 Y 1 A THR 102 ? A THR 102 
103 1 Y 1 A GLY 103 ? A GLY 103 
104 1 Y 1 A VAL 104 ? A VAL 104 
105 1 Y 1 A THR 105 ? A THR 105 
106 1 Y 1 A THR 106 ? A THR 106 
107 1 Y 1 A LEU 107 ? A LEU 107 
108 1 Y 1 A ARG 108 ? A ARG 108 
109 1 Y 1 A GLN 109 ? A GLN 109 
110 1 Y 1 A ARG 110 ? A ARG 110 
111 1 Y 1 A ARG 111 ? A ARG 111 
112 1 Y 1 A LYS 112 ? A LYS 112 
113 1 Y 1 A PRO 113 ? A PRO 113 
114 1 Y 1 A VAL 114 ? A VAL 114 
115 1 Y 1 A PHE 115 ? A PHE 115 
116 1 Y 1 A HIS 116 ? A HIS 116 
117 1 Y 1 A LEU 117 ? A LEU 117 
118 1 Y 1 A SER 118 ? A SER 118 
119 1 Y 1 A HIS 119 ? A HIS 119 
120 1 Y 1 A GLU 120 ? A GLU 120 
121 1 Y 1 A GLU 121 ? A GLU 121 
122 1 Y 1 A ARG 122 ? A ARG 122 
123 1 Y 1 A VAL 123 ? A VAL 123 
124 1 Y 1 A GLN 124 ? A GLN 124 
125 1 Y 1 A HIS 125 ? A HIS 125 
126 1 Y 1 A ARG 126 ? A ARG 126 
127 1 Y 1 A ASN 127 ? A ASN 127 
128 1 Y 1 A ILE 128 ? A ILE 128 
129 1 Y 1 A LYS 129 ? A LYS 129 
130 1 Y 1 A ASP 130 ? A ASP 130 
131 1 Y 1 A LEU 131 ? A LEU 131 
132 1 Y 1 A LYS 132 ? A LYS 132 
133 1 Y 1 A LEU 133 ? A LEU 133 
134 1 Y 1 A ALA 134 ? A ALA 134 
135 1 Y 1 A PHE 135 ? A PHE 135 
136 1 Y 1 A SER 136 ? A SER 136 
137 1 Y 1 A GLU 137 ? A GLU 137 
138 1 Y 1 A PHE 138 ? A PHE 138 
139 1 Y 1 A TYR 139 ? A TYR 139 
140 1 Y 1 A LEU 140 ? A LEU 140 
141 1 Y 1 A SER 141 ? A SER 141 
142 1 Y 1 A LEU 142 ? A LEU 142 
143 1 Y 1 A ILE 143 ? A ILE 143 
144 1 Y 1 A LEU 144 ? A LEU 144 
145 1 Y 1 A LEU 145 ? A LEU 145 
146 1 Y 1 A GLN 146 ? A GLN 146 
147 1 Y 1 A ASN 147 ? A ASN 147 
148 1 Y 1 A TYR 148 ? A TYR 148 
149 1 Y 1 A GLN 149 ? A GLN 149 
150 1 Y 1 A ASN 150 ? A ASN 150 
151 1 Y 1 A LEU 151 ? A LEU 151 
152 1 Y 1 A ASN 152 ? A ASN 152 
153 1 Y 1 A PHE 153 ? A PHE 153 
154 1 Y 1 A THR 154 ? A THR 154 
155 1 Y 1 A GLY 155 ? A GLY 155 
156 1 Y 1 A PHE 156 ? A PHE 156 
157 1 Y 1 A ARG 157 ? A ARG 157 
158 1 Y 1 A LYS 158 ? A LYS 158 
159 1 Y 1 A ILE 159 ? A ILE 159 
160 1 Y 1 A LEU 160 ? A LEU 160 
161 1 Y 1 A LYS 161 ? A LYS 161 
162 1 Y 1 A LYS 162 ? A LYS 162 
163 1 Y 1 A HIS 163 ? A HIS 163 
164 1 Y 1 A ASP 164 ? A ASP 164 
165 1 Y 1 A LYS 165 ? A LYS 165 
166 1 Y 1 A ILE 166 ? A ILE 166 
167 1 Y 1 A LEU 167 ? A LEU 167 
168 1 Y 1 A GLU 168 ? A GLU 168 
169 1 Y 1 A THR 169 ? A THR 169 
170 1 Y 1 A SER 170 ? A SER 170 
171 1 Y 1 A ARG 171 ? A ARG 171 
172 1 Y 1 A GLY 172 ? A GLY 172 
173 1 Y 1 A ALA 173 ? A ALA 173 
174 1 Y 1 A ASP 174 ? A ASP 174 
175 1 Y 1 A TRP 175 ? A TRP 175 
176 1 Y 1 A ARG 176 ? A ARG 176 
177 1 Y 1 A VAL 177 ? A VAL 177 
178 1 Y 1 A ALA 178 ? A ALA 178 
179 1 Y 1 A HIS 179 ? A HIS 179 
180 1 Y 1 A VAL 180 ? A VAL 180 
181 1 Y 1 A GLU 181 ? A GLU 181 
182 1 Y 1 A VAL 182 ? A VAL 182 
183 1 Y 1 A ALA 183 ? A ALA 183 
184 1 Y 1 A PRO 184 ? A PRO 184 
185 1 Y 1 A PHE 185 ? A PHE 185 
186 1 Y 1 A TYR 186 ? A TYR 186 
187 1 Y 1 A THR 187 ? A THR 187 
188 1 Y 1 A CYS 188 ? A CYS 188 
189 1 Y 1 A LYS 189 ? A LYS 189 
190 1 Y 1 A LYS 190 ? A LYS 190 
191 1 Y 1 A ILE 191 ? A ILE 191 
192 1 Y 1 A ASN 192 ? A ASN 192 
193 1 Y 1 A GLN 193 ? A GLN 193 
194 1 Y 1 A LEU 194 ? A LEU 194 
195 1 Y 1 A ILE 195 ? A ILE 195 
196 1 Y 1 A SER 196 ? A SER 196 
197 1 Y 1 A GLU 197 ? A GLU 197 
198 1 Y 1 A THR 198 ? A THR 198 
199 1 Y 1 A GLU 199 ? A GLU 199 
200 1 Y 1 A ALA 200 ? A ALA 200 
201 1 Y 1 A VAL 201 ? A VAL 201 
202 1 Y 1 A VAL 202 ? A VAL 202 
203 1 Y 1 A THR 203 ? A THR 203 
204 1 Y 1 A ASN 204 ? A ASN 204 
205 1 Y 1 A GLU 205 ? A GLU 205 
206 1 Y 1 A LEU 206 ? A LEU 206 
207 1 Y 1 A GLU 207 ? A GLU 207 
208 1 Y 1 A ASP 208 ? A ASP 208 
209 1 Y 1 A GLY 209 ? A GLY 209 
210 1 Y 1 A ASP 210 ? A ASP 210 
211 1 Y 1 A ARG 211 ? A ARG 211 
212 1 Y 1 A GLN 212 ? A GLN 212 
213 1 Y 1 A LYS 213 ? A LYS 213 
214 1 Y 1 A ALA 214 ? A ALA 214 
215 1 Y 1 A MET 215 ? A MET 215 
216 1 Y 1 A LYS 216 ? A LYS 216 
217 1 Y 1 A ARG 217 ? A ARG 217 
218 1 Y 1 A LEU 218 ? A LEU 218 
219 1 Y 1 A ARG 219 ? A ARG 219 
220 1 Y 1 A VAL 220 ? A VAL 220 
221 1 Y 1 A PRO 221 ? A PRO 221 
222 1 Y 1 A PRO 222 ? A PRO 222 
223 1 Y 1 A LEU 223 ? A LEU 223 
224 1 Y 1 A GLY 224 ? A GLY 224 
225 1 Y 1 A ALA 225 ? A ALA 225 
226 1 Y 1 A ALA 226 ? A ALA 226 
227 1 Y 1 A GLN 227 ? A GLN 227 
228 1 Y 1 A PRO 228 ? A PRO 228 
229 1 Y 1 A ASN 432 ? A ASN 432 
230 1 Y 1 A ASN 433 ? A ASN 433 
231 1 Y 1 A SER 434 ? A SER 434 
232 1 Y 1 A GLU 435 ? A GLU 435 
233 1 Y 1 A GLU 436 ? A GLU 436 
234 1 Y 1 A SER 437 ? A SER 437 
235 1 Y 1 A GLY 438 ? A GLY 438 
236 1 Y 1 A ILE 439 ? A ILE 439 
237 1 Y 1 A CYS 440 ? A CYS 440 
238 1 Y 1 A HIS 441 ? A HIS 441 
239 1 Y 1 A LYS 442 ? A LYS 442 
240 1 Y 1 A TYR 443 ? A TYR 443 
241 1 Y 1 A THR 444 ? A THR 444 
242 1 Y 1 A TYR 445 ? A TYR 445 
243 1 Y 1 A ALA 625 ? A ALA 625 
244 1 Y 1 A VAL 626 ? A VAL 626 
245 1 Y 1 A ARG 627 ? A ARG 627 
246 1 Y 1 A ASP 628 ? A ASP 628 
247 1 Y 1 A ILE 629 ? A ILE 629 
248 1 Y 1 A SER 630 ? A SER 630 
249 1 Y 1 A VAL 631 ? A VAL 631 
250 1 Y 1 A ALA 632 ? A ALA 632 
251 1 Y 1 A PRO 633 ? A PRO 633 
252 1 Y 1 A LEU 634 ? A LEU 634 
253 1 Y 1 A ASN 635 ? A ASN 635 
254 1 Y 1 A ALA 636 ? A ALA 636 
255 1 Y 1 A ASP 637 ? A ASP 637 
256 1 Y 1 A ASP 638 ? A ASP 638 
257 1 Y 1 A GLN 639 ? A GLN 639 
258 1 Y 1 A THR 640 ? A THR 640 
259 1 Y 1 A LEU 641 ? A LEU 641 
260 1 Y 1 A LEU 642 ? A LEU 642 
261 1 Y 1 A GLU 643 ? A GLU 643 
262 1 Y 1 A GLN 644 ? A GLN 644 
263 1 Y 1 A MET 645 ? A MET 645 
264 1 Y 1 A MET 646 ? A MET 646 
265 1 Y 1 A ASP 647 ? A ASP 647 
266 1 Y 1 A GLN 648 ? A GLN 648 
267 1 Y 1 A ASP 649 ? A ASP 649 
268 1 Y 1 A ASP 650 ? A ASP 650 
269 1 Y 1 A GLY 651 ? A GLY 651 
270 1 Y 1 A VAL 652 ? A VAL 652 
271 1 Y 1 A ARG 653 ? A ARG 653 
272 1 Y 1 A ASN 654 ? A ASN 654 
273 1 Y 1 A ARG 655 ? A ARG 655 
274 1 Y 1 A GLN 656 ? A GLN 656 
275 1 Y 1 A LYS 657 ? A LYS 657 
276 1 Y 1 A ASN 658 ? A ASN 658 
277 1 Y 1 A ARG 659 ? A ARG 659 
278 1 Y 1 A SER 660 ? A SER 660 
279 1 Y 1 A TRP 661 ? A TRP 661 
280 1 Y 1 A LYS 662 ? A LYS 662 
281 1 Y 1 A TYR 663 ? A TYR 663 
282 1 Y 1 A ASN 664 ? A ASN 664 
283 1 Y 1 A GLN 665 ? A GLN 665 
284 1 Y 1 A SER 666 ? A SER 666 
285 1 Y 1 A ILE 667 ? A ILE 667 
286 1 Y 1 A SER 668 ? A SER 668 
287 1 Y 1 A LEU 669 ? A LEU 669 
288 1 Y 1 A ARG 670 ? A ARG 670 
289 1 Y 1 A ARG 671 ? A ARG 671 
290 1 Y 1 A PRO 672 ? A PRO 672 
291 1 Y 1 A ARG 673 ? A ARG 673 
292 1 Y 1 A LEU 674 ? A LEU 674 
293 1 Y 1 A ALA 675 ? A ALA 675 
294 1 Y 1 A SER 676 ? A SER 676 
295 1 Y 1 A GLN 677 ? A GLN 677 
296 1 Y 1 A SER 678 ? A SER 678 
297 1 Y 1 A LYS 679 ? A LYS 679 
298 1 Y 1 A ALA 680 ? A ALA 680 
299 1 Y 1 A ARG 681 ? A ARG 681 
300 1 Y 1 A ASP 682 ? A ASP 682 
301 1 Y 1 A THR 683 ? A THR 683 
302 1 Y 1 A LYS 684 ? A LYS 684 
303 1 Y 1 A VAL 685 ? A VAL 685 
304 1 Y 1 A LEU 686 ? A LEU 686 
305 1 Y 1 A ILE 687 ? A ILE 687 
306 1 Y 1 A GLU 688 ? A GLU 688 
307 1 Y 1 A ASP 689 ? A ASP 689 
308 1 Y 1 A THR 690 ? A THR 690 
309 1 Y 1 A ASP 691 ? A ASP 691 
310 1 Y 1 A ASP 692 ? A ASP 692 
311 1 Y 1 A GLU 693 ? A GLU 693 
312 1 Y 1 A ALA 694 ? A ALA 694 
313 1 Y 1 A ASN 695 ? A ASN 695 
314 1 Y 1 A THR 696 ? A THR 696 
315 1 Y 1 A LEU 697 ? A LEU 697 
316 1 Y 1 A GLU 698 ? A GLU 698 
317 1 Y 1 A ASP 699 ? A ASP 699 
318 1 Y 1 A TYR 700 ? A TYR 700 
319 1 Y 1 A LYS 701 ? A LYS 701 
320 1 Y 1 A ASP 702 ? A ASP 702 
321 1 Y 1 A HIS 703 ? A HIS 703 
322 1 Y 1 A ASP 704 ? A ASP 704 
323 1 Y 1 A GLY 705 ? A GLY 705 
324 1 Y 1 A ASP 706 ? A ASP 706 
325 1 Y 1 A TYR 707 ? A TYR 707 
326 1 Y 1 A LYS 708 ? A LYS 708 
327 1 Y 1 A ASP 709 ? A ASP 709 
328 1 Y 1 A HIS 710 ? A HIS 710 
329 1 Y 1 A ASP 711 ? A ASP 711 
330 1 Y 1 A ILE 712 ? A ILE 712 
331 1 Y 1 A ASP 713 ? A ASP 713 
332 1 Y 1 A TYR 714 ? A TYR 714 
333 1 Y 1 A LYS 715 ? A LYS 715 
334 1 Y 1 A ASP 716 ? A ASP 716 
335 1 Y 1 A ASP 717 ? A ASP 717 
336 1 Y 1 A ASP 718 ? A ASP 718 
337 1 Y 1 A ASP 719 ? A ASP 719 
338 1 Y 1 A LYS 720 ? A LYS 720 
339 1 Y 1 B MET 1   ? B MET 1   
340 1 Y 1 B LYS 2   ? B LYS 2   
341 1 Y 1 B PHE 3   ? B PHE 3   
342 1 Y 1 B ALA 4   ? B ALA 4   
343 1 Y 1 B GLU 5   ? B GLU 5   
344 1 Y 1 B HIS 6   ? B HIS 6   
345 1 Y 1 B LEU 7   ? B LEU 7   
346 1 Y 1 B SER 8   ? B SER 8   
347 1 Y 1 B ALA 9   ? B ALA 9   
348 1 Y 1 B HIS 10  ? B HIS 10  
349 1 Y 1 B ILE 11  ? B ILE 11  
350 1 Y 1 B THR 12  ? B THR 12  
351 1 Y 1 B PRO 13  ? B PRO 13  
352 1 Y 1 B GLU 14  ? B GLU 14  
353 1 Y 1 B TRP 15  ? B TRP 15  
354 1 Y 1 B ARG 16  ? B ARG 16  
355 1 Y 1 B LYS 17  ? B LYS 17  
356 1 Y 1 B GLN 18  ? B GLN 18  
357 1 Y 1 B TYR 19  ? B TYR 19  
358 1 Y 1 B ILE 20  ? B ILE 20  
359 1 Y 1 B GLN 21  ? B GLN 21  
360 1 Y 1 B TYR 22  ? B TYR 22  
361 1 Y 1 B GLU 23  ? B GLU 23  
362 1 Y 1 B ALA 24  ? B ALA 24  
363 1 Y 1 B PHE 25  ? B PHE 25  
364 1 Y 1 B LYS 26  ? B LYS 26  
365 1 Y 1 B ASP 27  ? B ASP 27  
366 1 Y 1 B MET 28  ? B MET 28  
367 1 Y 1 B LEU 29  ? B LEU 29  
368 1 Y 1 B TYR 30  ? B TYR 30  
369 1 Y 1 B SER 31  ? B SER 31  
370 1 Y 1 B ALA 32  ? B ALA 32  
371 1 Y 1 B GLN 33  ? B GLN 33  
372 1 Y 1 B ASP 34  ? B ASP 34  
373 1 Y 1 B GLN 35  ? B GLN 35  
374 1 Y 1 B ALA 36  ? B ALA 36  
375 1 Y 1 B PRO 37  ? B PRO 37  
376 1 Y 1 B SER 38  ? B SER 38  
377 1 Y 1 B VAL 39  ? B VAL 39  
378 1 Y 1 B GLU 40  ? B GLU 40  
379 1 Y 1 B VAL 41  ? B VAL 41  
380 1 Y 1 B THR 42  ? B THR 42  
381 1 Y 1 B ASP 43  ? B ASP 43  
382 1 Y 1 B GLU 44  ? B GLU 44  
383 1 Y 1 B ASP 45  ? B ASP 45  
384 1 Y 1 B THR 46  ? B THR 46  
385 1 Y 1 B VAL 47  ? B VAL 47  
386 1 Y 1 B LYS 48  ? B LYS 48  
387 1 Y 1 B ARG 49  ? B ARG 49  
388 1 Y 1 B TYR 50  ? B TYR 50  
389 1 Y 1 B PHE 51  ? B PHE 51  
390 1 Y 1 B ALA 52  ? B ALA 52  
391 1 Y 1 B LYS 53  ? B LYS 53  
392 1 Y 1 B PHE 54  ? B PHE 54  
393 1 Y 1 B GLU 55  ? B GLU 55  
394 1 Y 1 B GLU 56  ? B GLU 56  
395 1 Y 1 B LYS 57  ? B LYS 57  
396 1 Y 1 B PHE 58  ? B PHE 58  
397 1 Y 1 B PHE 59  ? B PHE 59  
398 1 Y 1 B GLN 60  ? B GLN 60  
399 1 Y 1 B THR 61  ? B THR 61  
400 1 Y 1 B CYS 62  ? B CYS 62  
401 1 Y 1 B GLU 63  ? B GLU 63  
402 1 Y 1 B LYS 64  ? B LYS 64  
403 1 Y 1 B GLU 65  ? B GLU 65  
404 1 Y 1 B LEU 66  ? B LEU 66  
405 1 Y 1 B ALA 67  ? B ALA 67  
406 1 Y 1 B LYS 68  ? B LYS 68  
407 1 Y 1 B ILE 69  ? B ILE 69  
408 1 Y 1 B ASN 70  ? B ASN 70  
409 1 Y 1 B THR 71  ? B THR 71  
410 1 Y 1 B PHE 72  ? B PHE 72  
411 1 Y 1 B TYR 73  ? B TYR 73  
412 1 Y 1 B SER 74  ? B SER 74  
413 1 Y 1 B GLU 75  ? B GLU 75  
414 1 Y 1 B LYS 76  ? B LYS 76  
415 1 Y 1 B LEU 77  ? B LEU 77  
416 1 Y 1 B ALA 78  ? B ALA 78  
417 1 Y 1 B GLU 79  ? B GLU 79  
418 1 Y 1 B ALA 80  ? B ALA 80  
419 1 Y 1 B GLN 81  ? B GLN 81  
420 1 Y 1 B ARG 82  ? B ARG 82  
421 1 Y 1 B ARG 83  ? B ARG 83  
422 1 Y 1 B PHE 84  ? B PHE 84  
423 1 Y 1 B ALA 85  ? B ALA 85  
424 1 Y 1 B THR 86  ? B THR 86  
425 1 Y 1 B LEU 87  ? B LEU 87  
426 1 Y 1 B GLN 88  ? B GLN 88  
427 1 Y 1 B ASN 89  ? B ASN 89  
428 1 Y 1 B GLU 90  ? B GLU 90  
429 1 Y 1 B LEU 91  ? B LEU 91  
430 1 Y 1 B GLN 92  ? B GLN 92  
431 1 Y 1 B SER 93  ? B SER 93  
432 1 Y 1 B SER 94  ? B SER 94  
433 1 Y 1 B LEU 95  ? B LEU 95  
434 1 Y 1 B ASP 96  ? B ASP 96  
435 1 Y 1 B ALA 97  ? B ALA 97  
436 1 Y 1 B GLN 98  ? B GLN 98  
437 1 Y 1 B LYS 99  ? B LYS 99  
438 1 Y 1 B GLU 100 ? B GLU 100 
439 1 Y 1 B SER 101 ? B SER 101 
440 1 Y 1 B THR 102 ? B THR 102 
441 1 Y 1 B GLY 103 ? B GLY 103 
442 1 Y 1 B VAL 104 ? B VAL 104 
443 1 Y 1 B THR 105 ? B THR 105 
444 1 Y 1 B THR 106 ? B THR 106 
445 1 Y 1 B LEU 107 ? B LEU 107 
446 1 Y 1 B ARG 108 ? B ARG 108 
447 1 Y 1 B GLN 109 ? B GLN 109 
448 1 Y 1 B ARG 110 ? B ARG 110 
449 1 Y 1 B ARG 111 ? B ARG 111 
450 1 Y 1 B LYS 112 ? B LYS 112 
451 1 Y 1 B PRO 113 ? B PRO 113 
452 1 Y 1 B VAL 114 ? B VAL 114 
453 1 Y 1 B PHE 115 ? B PHE 115 
454 1 Y 1 B HIS 116 ? B HIS 116 
455 1 Y 1 B LEU 117 ? B LEU 117 
456 1 Y 1 B SER 118 ? B SER 118 
457 1 Y 1 B HIS 119 ? B HIS 119 
458 1 Y 1 B GLU 120 ? B GLU 120 
459 1 Y 1 B GLU 121 ? B GLU 121 
460 1 Y 1 B ARG 122 ? B ARG 122 
461 1 Y 1 B VAL 123 ? B VAL 123 
462 1 Y 1 B GLN 124 ? B GLN 124 
463 1 Y 1 B HIS 125 ? B HIS 125 
464 1 Y 1 B ARG 126 ? B ARG 126 
465 1 Y 1 B ASN 127 ? B ASN 127 
466 1 Y 1 B ILE 128 ? B ILE 128 
467 1 Y 1 B LYS 129 ? B LYS 129 
468 1 Y 1 B ASP 130 ? B ASP 130 
469 1 Y 1 B LEU 131 ? B LEU 131 
470 1 Y 1 B LYS 132 ? B LYS 132 
471 1 Y 1 B LEU 133 ? B LEU 133 
472 1 Y 1 B ALA 134 ? B ALA 134 
473 1 Y 1 B PHE 135 ? B PHE 135 
474 1 Y 1 B SER 136 ? B SER 136 
475 1 Y 1 B GLU 137 ? B GLU 137 
476 1 Y 1 B PHE 138 ? B PHE 138 
477 1 Y 1 B TYR 139 ? B TYR 139 
478 1 Y 1 B LEU 140 ? B LEU 140 
479 1 Y 1 B SER 141 ? B SER 141 
480 1 Y 1 B LEU 142 ? B LEU 142 
481 1 Y 1 B ILE 143 ? B ILE 143 
482 1 Y 1 B LEU 144 ? B LEU 144 
483 1 Y 1 B LEU 145 ? B LEU 145 
484 1 Y 1 B GLN 146 ? B GLN 146 
485 1 Y 1 B ASN 147 ? B ASN 147 
486 1 Y 1 B TYR 148 ? B TYR 148 
487 1 Y 1 B GLN 149 ? B GLN 149 
488 1 Y 1 B ASN 150 ? B ASN 150 
489 1 Y 1 B LEU 151 ? B LEU 151 
490 1 Y 1 B ASN 152 ? B ASN 152 
491 1 Y 1 B PHE 153 ? B PHE 153 
492 1 Y 1 B THR 154 ? B THR 154 
493 1 Y 1 B GLY 155 ? B GLY 155 
494 1 Y 1 B PHE 156 ? B PHE 156 
495 1 Y 1 B ARG 157 ? B ARG 157 
496 1 Y 1 B LYS 158 ? B LYS 158 
497 1 Y 1 B ILE 159 ? B ILE 159 
498 1 Y 1 B LEU 160 ? B LEU 160 
499 1 Y 1 B LYS 161 ? B LYS 161 
500 1 Y 1 B LYS 162 ? B LYS 162 
501 1 Y 1 B HIS 163 ? B HIS 163 
502 1 Y 1 B ASP 164 ? B ASP 164 
503 1 Y 1 B LYS 165 ? B LYS 165 
504 1 Y 1 B ILE 166 ? B ILE 166 
505 1 Y 1 B LEU 167 ? B LEU 167 
506 1 Y 1 B GLU 168 ? B GLU 168 
507 1 Y 1 B THR 169 ? B THR 169 
508 1 Y 1 B SER 170 ? B SER 170 
509 1 Y 1 B ARG 171 ? B ARG 171 
510 1 Y 1 B GLY 172 ? B GLY 172 
511 1 Y 1 B ALA 173 ? B ALA 173 
512 1 Y 1 B ASP 174 ? B ASP 174 
513 1 Y 1 B TRP 175 ? B TRP 175 
514 1 Y 1 B ARG 176 ? B ARG 176 
515 1 Y 1 B VAL 177 ? B VAL 177 
516 1 Y 1 B ALA 178 ? B ALA 178 
517 1 Y 1 B HIS 179 ? B HIS 179 
518 1 Y 1 B VAL 180 ? B VAL 180 
519 1 Y 1 B GLU 181 ? B GLU 181 
520 1 Y 1 B VAL 182 ? B VAL 182 
521 1 Y 1 B ALA 183 ? B ALA 183 
522 1 Y 1 B PRO 184 ? B PRO 184 
523 1 Y 1 B PHE 185 ? B PHE 185 
524 1 Y 1 B TYR 186 ? B TYR 186 
525 1 Y 1 B THR 187 ? B THR 187 
526 1 Y 1 B CYS 188 ? B CYS 188 
527 1 Y 1 B LYS 189 ? B LYS 189 
528 1 Y 1 B LYS 190 ? B LYS 190 
529 1 Y 1 B ILE 191 ? B ILE 191 
530 1 Y 1 B ASN 192 ? B ASN 192 
531 1 Y 1 B GLN 193 ? B GLN 193 
532 1 Y 1 B LEU 194 ? B LEU 194 
533 1 Y 1 B ILE 195 ? B ILE 195 
534 1 Y 1 B SER 196 ? B SER 196 
535 1 Y 1 B GLU 197 ? B GLU 197 
536 1 Y 1 B THR 198 ? B THR 198 
537 1 Y 1 B GLU 199 ? B GLU 199 
538 1 Y 1 B ALA 200 ? B ALA 200 
539 1 Y 1 B VAL 201 ? B VAL 201 
540 1 Y 1 B VAL 202 ? B VAL 202 
541 1 Y 1 B THR 203 ? B THR 203 
542 1 Y 1 B ASN 204 ? B ASN 204 
543 1 Y 1 B GLU 205 ? B GLU 205 
544 1 Y 1 B LEU 206 ? B LEU 206 
545 1 Y 1 B GLU 207 ? B GLU 207 
546 1 Y 1 B ASP 208 ? B ASP 208 
547 1 Y 1 B GLY 209 ? B GLY 209 
548 1 Y 1 B ASP 210 ? B ASP 210 
549 1 Y 1 B ARG 211 ? B ARG 211 
550 1 Y 1 B GLN 212 ? B GLN 212 
551 1 Y 1 B LYS 213 ? B LYS 213 
552 1 Y 1 B ALA 214 ? B ALA 214 
553 1 Y 1 B MET 215 ? B MET 215 
554 1 Y 1 B LYS 216 ? B LYS 216 
555 1 Y 1 B ARG 217 ? B ARG 217 
556 1 Y 1 B LEU 218 ? B LEU 218 
557 1 Y 1 B ARG 219 ? B ARG 219 
558 1 Y 1 B VAL 220 ? B VAL 220 
559 1 Y 1 B PRO 221 ? B PRO 221 
560 1 Y 1 B PRO 222 ? B PRO 222 
561 1 Y 1 B LEU 223 ? B LEU 223 
562 1 Y 1 B GLY 224 ? B GLY 224 
563 1 Y 1 B ALA 225 ? B ALA 225 
564 1 Y 1 B ALA 226 ? B ALA 226 
565 1 Y 1 B GLN 227 ? B GLN 227 
566 1 Y 1 B PRO 228 ? B PRO 228 
567 1 Y 1 B ASN 432 ? B ASN 432 
568 1 Y 1 B ASN 433 ? B ASN 433 
569 1 Y 1 B SER 434 ? B SER 434 
570 1 Y 1 B GLU 435 ? B GLU 435 
571 1 Y 1 B GLU 436 ? B GLU 436 
572 1 Y 1 B SER 437 ? B SER 437 
573 1 Y 1 B GLY 438 ? B GLY 438 
574 1 Y 1 B ILE 439 ? B ILE 439 
575 1 Y 1 B CYS 440 ? B CYS 440 
576 1 Y 1 B HIS 441 ? B HIS 441 
577 1 Y 1 B LYS 442 ? B LYS 442 
578 1 Y 1 B TYR 443 ? B TYR 443 
579 1 Y 1 B THR 444 ? B THR 444 
580 1 Y 1 B TYR 445 ? B TYR 445 
581 1 Y 1 B ALA 625 ? B ALA 625 
582 1 Y 1 B VAL 626 ? B VAL 626 
583 1 Y 1 B ARG 627 ? B ARG 627 
584 1 Y 1 B ASP 628 ? B ASP 628 
585 1 Y 1 B ILE 629 ? B ILE 629 
586 1 Y 1 B SER 630 ? B SER 630 
587 1 Y 1 B VAL 631 ? B VAL 631 
588 1 Y 1 B ALA 632 ? B ALA 632 
589 1 Y 1 B PRO 633 ? B PRO 633 
590 1 Y 1 B LEU 634 ? B LEU 634 
591 1 Y 1 B ASN 635 ? B ASN 635 
592 1 Y 1 B ALA 636 ? B ALA 636 
593 1 Y 1 B ASP 637 ? B ASP 637 
594 1 Y 1 B ASP 638 ? B ASP 638 
595 1 Y 1 B GLN 639 ? B GLN 639 
596 1 Y 1 B THR 640 ? B THR 640 
597 1 Y 1 B LEU 641 ? B LEU 641 
598 1 Y 1 B LEU 642 ? B LEU 642 
599 1 Y 1 B GLU 643 ? B GLU 643 
600 1 Y 1 B GLN 644 ? B GLN 644 
601 1 Y 1 B MET 645 ? B MET 645 
602 1 Y 1 B MET 646 ? B MET 646 
603 1 Y 1 B ASP 647 ? B ASP 647 
604 1 Y 1 B GLN 648 ? B GLN 648 
605 1 Y 1 B ASP 649 ? B ASP 649 
606 1 Y 1 B ASP 650 ? B ASP 650 
607 1 Y 1 B GLY 651 ? B GLY 651 
608 1 Y 1 B VAL 652 ? B VAL 652 
609 1 Y 1 B ARG 653 ? B ARG 653 
610 1 Y 1 B ASN 654 ? B ASN 654 
611 1 Y 1 B ARG 655 ? B ARG 655 
612 1 Y 1 B GLN 656 ? B GLN 656 
613 1 Y 1 B LYS 657 ? B LYS 657 
614 1 Y 1 B ASN 658 ? B ASN 658 
615 1 Y 1 B ARG 659 ? B ARG 659 
616 1 Y 1 B SER 660 ? B SER 660 
617 1 Y 1 B TRP 661 ? B TRP 661 
618 1 Y 1 B LYS 662 ? B LYS 662 
619 1 Y 1 B TYR 663 ? B TYR 663 
620 1 Y 1 B ASN 664 ? B ASN 664 
621 1 Y 1 B GLN 665 ? B GLN 665 
622 1 Y 1 B SER 666 ? B SER 666 
623 1 Y 1 B ILE 667 ? B ILE 667 
624 1 Y 1 B SER 668 ? B SER 668 
625 1 Y 1 B LEU 669 ? B LEU 669 
626 1 Y 1 B ARG 670 ? B ARG 670 
627 1 Y 1 B ARG 671 ? B ARG 671 
628 1 Y 1 B PRO 672 ? B PRO 672 
629 1 Y 1 B ARG 673 ? B ARG 673 
630 1 Y 1 B LEU 674 ? B LEU 674 
631 1 Y 1 B ALA 675 ? B ALA 675 
632 1 Y 1 B SER 676 ? B SER 676 
633 1 Y 1 B GLN 677 ? B GLN 677 
634 1 Y 1 B SER 678 ? B SER 678 
635 1 Y 1 B LYS 679 ? B LYS 679 
636 1 Y 1 B ALA 680 ? B ALA 680 
637 1 Y 1 B ARG 681 ? B ARG 681 
638 1 Y 1 B ASP 682 ? B ASP 682 
639 1 Y 1 B THR 683 ? B THR 683 
640 1 Y 1 B LYS 684 ? B LYS 684 
641 1 Y 1 B VAL 685 ? B VAL 685 
642 1 Y 1 B LEU 686 ? B LEU 686 
643 1 Y 1 B ILE 687 ? B ILE 687 
644 1 Y 1 B GLU 688 ? B GLU 688 
645 1 Y 1 B ASP 689 ? B ASP 689 
646 1 Y 1 B THR 690 ? B THR 690 
647 1 Y 1 B ASP 691 ? B ASP 691 
648 1 Y 1 B ASP 692 ? B ASP 692 
649 1 Y 1 B GLU 693 ? B GLU 693 
650 1 Y 1 B ALA 694 ? B ALA 694 
651 1 Y 1 B ASN 695 ? B ASN 695 
652 1 Y 1 B THR 696 ? B THR 696 
653 1 Y 1 B LEU 697 ? B LEU 697 
654 1 Y 1 B GLU 698 ? B GLU 698 
655 1 Y 1 B ASP 699 ? B ASP 699 
656 1 Y 1 B TYR 700 ? B TYR 700 
657 1 Y 1 B LYS 701 ? B LYS 701 
658 1 Y 1 B ASP 702 ? B ASP 702 
659 1 Y 1 B HIS 703 ? B HIS 703 
660 1 Y 1 B ASP 704 ? B ASP 704 
661 1 Y 1 B GLY 705 ? B GLY 705 
662 1 Y 1 B ASP 706 ? B ASP 706 
663 1 Y 1 B TYR 707 ? B TYR 707 
664 1 Y 1 B LYS 708 ? B LYS 708 
665 1 Y 1 B ASP 709 ? B ASP 709 
666 1 Y 1 B HIS 710 ? B HIS 710 
667 1 Y 1 B ASP 711 ? B ASP 711 
668 1 Y 1 B ILE 712 ? B ILE 712 
669 1 Y 1 B ASP 713 ? B ASP 713 
670 1 Y 1 B TYR 714 ? B TYR 714 
671 1 Y 1 B LYS 715 ? B LYS 715 
672 1 Y 1 B ASP 716 ? B ASP 716 
673 1 Y 1 B ASP 717 ? B ASP 717 
674 1 Y 1 B ASP 718 ? B ASP 718 
675 1 Y 1 B ASP 719 ? B ASP 719 
676 1 Y 1 B LYS 720 ? B LYS 720 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PC1 O12  O N N 247 
PC1 P    P N N 248 
PC1 O14  O N N 249 
PC1 O13  O N N 250 
PC1 C11  C N N 251 
PC1 C12  C N N 252 
PC1 N    N N N 253 
PC1 C13  C N N 254 
PC1 C14  C N N 255 
PC1 C15  C N N 256 
PC1 O11  O N N 257 
PC1 C1   C N N 258 
PC1 C2   C N R 259 
PC1 O21  O N N 260 
PC1 C21  C N N 261 
PC1 O22  O N N 262 
PC1 C22  C N N 263 
PC1 C23  C N N 264 
PC1 C24  C N N 265 
PC1 C25  C N N 266 
PC1 C26  C N N 267 
PC1 C27  C N N 268 
PC1 C28  C N N 269 
PC1 C29  C N N 270 
PC1 C2A  C N N 271 
PC1 C2B  C N N 272 
PC1 C2C  C N N 273 
PC1 C2D  C N N 274 
PC1 C2E  C N N 275 
PC1 C2F  C N N 276 
PC1 C2G  C N N 277 
PC1 C2H  C N N 278 
PC1 C2I  C N N 279 
PC1 C3   C N N 280 
PC1 O31  O N N 281 
PC1 C31  C N N 282 
PC1 O32  O N N 283 
PC1 C32  C N N 284 
PC1 C33  C N N 285 
PC1 C34  C N N 286 
PC1 C35  C N N 287 
PC1 C36  C N N 288 
PC1 C37  C N N 289 
PC1 C38  C N N 290 
PC1 C39  C N N 291 
PC1 C3A  C N N 292 
PC1 C3B  C N N 293 
PC1 C3C  C N N 294 
PC1 C3D  C N N 295 
PC1 C3E  C N N 296 
PC1 C3F  C N N 297 
PC1 C3G  C N N 298 
PC1 C3H  C N N 299 
PC1 C3I  C N N 300 
PC1 H111 H N N 301 
PC1 H112 H N N 302 
PC1 H121 H N N 303 
PC1 H122 H N N 304 
PC1 H131 H N N 305 
PC1 H132 H N N 306 
PC1 H133 H N N 307 
PC1 H141 H N N 308 
PC1 H142 H N N 309 
PC1 H143 H N N 310 
PC1 H151 H N N 311 
PC1 H152 H N N 312 
PC1 H153 H N N 313 
PC1 H11  H N N 314 
PC1 H12  H N N 315 
PC1 H2   H N N 316 
PC1 H221 H N N 317 
PC1 H222 H N N 318 
PC1 H231 H N N 319 
PC1 H232 H N N 320 
PC1 H241 H N N 321 
PC1 H242 H N N 322 
PC1 H251 H N N 323 
PC1 H252 H N N 324 
PC1 H261 H N N 325 
PC1 H262 H N N 326 
PC1 H271 H N N 327 
PC1 H272 H N N 328 
PC1 H281 H N N 329 
PC1 H282 H N N 330 
PC1 H291 H N N 331 
PC1 H292 H N N 332 
PC1 H2A1 H N N 333 
PC1 H2A2 H N N 334 
PC1 H2B1 H N N 335 
PC1 H2B2 H N N 336 
PC1 H2C1 H N N 337 
PC1 H2C2 H N N 338 
PC1 H2D1 H N N 339 
PC1 H2D2 H N N 340 
PC1 H2E1 H N N 341 
PC1 H2E2 H N N 342 
PC1 H2F1 H N N 343 
PC1 H2F2 H N N 344 
PC1 H2G1 H N N 345 
PC1 H2G2 H N N 346 
PC1 H2H1 H N N 347 
PC1 H2H2 H N N 348 
PC1 H2I1 H N N 349 
PC1 H2I2 H N N 350 
PC1 H2I3 H N N 351 
PC1 H31  H N N 352 
PC1 H32  H N N 353 
PC1 H321 H N N 354 
PC1 H322 H N N 355 
PC1 H331 H N N 356 
PC1 H332 H N N 357 
PC1 H341 H N N 358 
PC1 H342 H N N 359 
PC1 H351 H N N 360 
PC1 H352 H N N 361 
PC1 H361 H N N 362 
PC1 H362 H N N 363 
PC1 H371 H N N 364 
PC1 H372 H N N 365 
PC1 H381 H N N 366 
PC1 H382 H N N 367 
PC1 H391 H N N 368 
PC1 H392 H N N 369 
PC1 H3A1 H N N 370 
PC1 H3A2 H N N 371 
PC1 H3B1 H N N 372 
PC1 H3B2 H N N 373 
PC1 H3C1 H N N 374 
PC1 H3C2 H N N 375 
PC1 H3D1 H N N 376 
PC1 H3D2 H N N 377 
PC1 H3E1 H N N 378 
PC1 H3E2 H N N 379 
PC1 H3F1 H N N 380 
PC1 H3F2 H N N 381 
PC1 H3G1 H N N 382 
PC1 H3G2 H N N 383 
PC1 H3H1 H N N 384 
PC1 H3H2 H N N 385 
PC1 H3I1 H N N 386 
PC1 H3I2 H N N 387 
PC1 H3I3 H N N 388 
PHE N    N N N 389 
PHE CA   C N S 390 
PHE C    C N N 391 
PHE O    O N N 392 
PHE CB   C N N 393 
PHE CG   C Y N 394 
PHE CD1  C Y N 395 
PHE CD2  C Y N 396 
PHE CE1  C Y N 397 
PHE CE2  C Y N 398 
PHE CZ   C Y N 399 
PHE OXT  O N N 400 
PHE H    H N N 401 
PHE H2   H N N 402 
PHE HA   H N N 403 
PHE HB2  H N N 404 
PHE HB3  H N N 405 
PHE HD1  H N N 406 
PHE HD2  H N N 407 
PHE HE1  H N N 408 
PHE HE2  H N N 409 
PHE HZ   H N N 410 
PHE HXT  H N N 411 
PO4 P    P N N 412 
PO4 O1   O N N 413 
PO4 O2   O N N 414 
PO4 O3   O N N 415 
PO4 O4   O N N 416 
PRO N    N N N 417 
PRO CA   C N S 418 
PRO C    C N N 419 
PRO O    O N N 420 
PRO CB   C N N 421 
PRO CG   C N N 422 
PRO CD   C N N 423 
PRO OXT  O N N 424 
PRO H    H N N 425 
PRO HA   H N N 426 
PRO HB2  H N N 427 
PRO HB3  H N N 428 
PRO HG2  H N N 429 
PRO HG3  H N N 430 
PRO HD2  H N N 431 
PRO HD3  H N N 432 
PRO HXT  H N N 433 
SER N    N N N 434 
SER CA   C N S 435 
SER C    C N N 436 
SER O    O N N 437 
SER CB   C N N 438 
SER OG   O N N 439 
SER OXT  O N N 440 
SER H    H N N 441 
SER H2   H N N 442 
SER HA   H N N 443 
SER HB2  H N N 444 
SER HB3  H N N 445 
SER HG   H N N 446 
SER HXT  H N N 447 
THR N    N N N 448 
THR CA   C N S 449 
THR C    C N N 450 
THR O    O N N 451 
THR CB   C N R 452 
THR OG1  O N N 453 
THR CG2  C N N 454 
THR OXT  O N N 455 
THR H    H N N 456 
THR H2   H N N 457 
THR HA   H N N 458 
THR HB   H N N 459 
THR HG1  H N N 460 
THR HG21 H N N 461 
THR HG22 H N N 462 
THR HG23 H N N 463 
THR HXT  H N N 464 
TRP N    N N N 465 
TRP CA   C N S 466 
TRP C    C N N 467 
TRP O    O N N 468 
TRP CB   C N N 469 
TRP CG   C Y N 470 
TRP CD1  C Y N 471 
TRP CD2  C Y N 472 
TRP NE1  N Y N 473 
TRP CE2  C Y N 474 
TRP CE3  C Y N 475 
TRP CZ2  C Y N 476 
TRP CZ3  C Y N 477 
TRP CH2  C Y N 478 
TRP OXT  O N N 479 
TRP H    H N N 480 
TRP H2   H N N 481 
TRP HA   H N N 482 
TRP HB2  H N N 483 
TRP HB3  H N N 484 
TRP HD1  H N N 485 
TRP HE1  H N N 486 
TRP HE3  H N N 487 
TRP HZ2  H N N 488 
TRP HZ3  H N N 489 
TRP HH2  H N N 490 
TRP HXT  H N N 491 
TYR N    N N N 492 
TYR CA   C N S 493 
TYR C    C N N 494 
TYR O    O N N 495 
TYR CB   C N N 496 
TYR CG   C Y N 497 
TYR CD1  C Y N 498 
TYR CD2  C Y N 499 
TYR CE1  C Y N 500 
TYR CE2  C Y N 501 
TYR CZ   C Y N 502 
TYR OH   O N N 503 
TYR OXT  O N N 504 
TYR H    H N N 505 
TYR H2   H N N 506 
TYR HA   H N N 507 
TYR HB2  H N N 508 
TYR HB3  H N N 509 
TYR HD1  H N N 510 
TYR HD2  H N N 511 
TYR HE1  H N N 512 
TYR HE2  H N N 513 
TYR HH   H N N 514 
TYR HXT  H N N 515 
VAL N    N N N 516 
VAL CA   C N S 517 
VAL C    C N N 518 
VAL O    O N N 519 
VAL CB   C N N 520 
VAL CG1  C N N 521 
VAL CG2  C N N 522 
VAL OXT  O N N 523 
VAL H    H N N 524 
VAL H2   H N N 525 
VAL HA   H N N 526 
VAL HB   H N N 527 
VAL HG11 H N N 528 
VAL HG12 H N N 529 
VAL HG13 H N N 530 
VAL HG21 H N N 531 
VAL HG22 H N N 532 
VAL HG23 H N N 533 
VAL HXT  H N N 534 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PC1 O12 P    sing N N 235 
PC1 P   O14  doub N N 236 
PC1 P   O13  sing N N 237 
PC1 P   O11  sing N N 238 
PC1 O13 C11  sing N N 239 
PC1 C11 C12  sing N N 240 
PC1 C11 H111 sing N N 241 
PC1 C11 H112 sing N N 242 
PC1 C12 N    sing N N 243 
PC1 C12 H121 sing N N 244 
PC1 C12 H122 sing N N 245 
PC1 N   C13  sing N N 246 
PC1 N   C14  sing N N 247 
PC1 N   C15  sing N N 248 
PC1 C13 H131 sing N N 249 
PC1 C13 H132 sing N N 250 
PC1 C13 H133 sing N N 251 
PC1 C14 H141 sing N N 252 
PC1 C14 H142 sing N N 253 
PC1 C14 H143 sing N N 254 
PC1 C15 H151 sing N N 255 
PC1 C15 H152 sing N N 256 
PC1 C15 H153 sing N N 257 
PC1 O11 C1   sing N N 258 
PC1 C1  C2   sing N N 259 
PC1 C1  H11  sing N N 260 
PC1 C1  H12  sing N N 261 
PC1 C2  O21  sing N N 262 
PC1 C2  C3   sing N N 263 
PC1 C2  H2   sing N N 264 
PC1 O21 C21  sing N N 265 
PC1 C21 O22  doub N N 266 
PC1 C21 C22  sing N N 267 
PC1 C22 C23  sing N N 268 
PC1 C22 H221 sing N N 269 
PC1 C22 H222 sing N N 270 
PC1 C23 C24  sing N N 271 
PC1 C23 H231 sing N N 272 
PC1 C23 H232 sing N N 273 
PC1 C24 C25  sing N N 274 
PC1 C24 H241 sing N N 275 
PC1 C24 H242 sing N N 276 
PC1 C25 C26  sing N N 277 
PC1 C25 H251 sing N N 278 
PC1 C25 H252 sing N N 279 
PC1 C26 C27  sing N N 280 
PC1 C26 H261 sing N N 281 
PC1 C26 H262 sing N N 282 
PC1 C27 C28  sing N N 283 
PC1 C27 H271 sing N N 284 
PC1 C27 H272 sing N N 285 
PC1 C28 C29  sing N N 286 
PC1 C28 H281 sing N N 287 
PC1 C28 H282 sing N N 288 
PC1 C29 C2A  sing N N 289 
PC1 C29 H291 sing N N 290 
PC1 C29 H292 sing N N 291 
PC1 C2A C2B  sing N N 292 
PC1 C2A H2A1 sing N N 293 
PC1 C2A H2A2 sing N N 294 
PC1 C2B C2C  sing N N 295 
PC1 C2B H2B1 sing N N 296 
PC1 C2B H2B2 sing N N 297 
PC1 C2C C2D  sing N N 298 
PC1 C2C H2C1 sing N N 299 
PC1 C2C H2C2 sing N N 300 
PC1 C2D C2E  sing N N 301 
PC1 C2D H2D1 sing N N 302 
PC1 C2D H2D2 sing N N 303 
PC1 C2E C2F  sing N N 304 
PC1 C2E H2E1 sing N N 305 
PC1 C2E H2E2 sing N N 306 
PC1 C2F C2G  sing N N 307 
PC1 C2F H2F1 sing N N 308 
PC1 C2F H2F2 sing N N 309 
PC1 C2G C2H  sing N N 310 
PC1 C2G H2G1 sing N N 311 
PC1 C2G H2G2 sing N N 312 
PC1 C2H C2I  sing N N 313 
PC1 C2H H2H1 sing N N 314 
PC1 C2H H2H2 sing N N 315 
PC1 C2I H2I1 sing N N 316 
PC1 C2I H2I2 sing N N 317 
PC1 C2I H2I3 sing N N 318 
PC1 C3  O31  sing N N 319 
PC1 C3  H31  sing N N 320 
PC1 C3  H32  sing N N 321 
PC1 O31 C31  sing N N 322 
PC1 C31 O32  doub N N 323 
PC1 C31 C32  sing N N 324 
PC1 C32 C33  sing N N 325 
PC1 C32 H321 sing N N 326 
PC1 C32 H322 sing N N 327 
PC1 C33 C34  sing N N 328 
PC1 C33 H331 sing N N 329 
PC1 C33 H332 sing N N 330 
PC1 C34 C35  sing N N 331 
PC1 C34 H341 sing N N 332 
PC1 C34 H342 sing N N 333 
PC1 C35 C36  sing N N 334 
PC1 C35 H351 sing N N 335 
PC1 C35 H352 sing N N 336 
PC1 C36 C37  sing N N 337 
PC1 C36 H361 sing N N 338 
PC1 C36 H362 sing N N 339 
PC1 C37 C38  sing N N 340 
PC1 C37 H371 sing N N 341 
PC1 C37 H372 sing N N 342 
PC1 C38 C39  sing N N 343 
PC1 C38 H381 sing N N 344 
PC1 C38 H382 sing N N 345 
PC1 C39 C3A  sing N N 346 
PC1 C39 H391 sing N N 347 
PC1 C39 H392 sing N N 348 
PC1 C3A C3B  sing N N 349 
PC1 C3A H3A1 sing N N 350 
PC1 C3A H3A2 sing N N 351 
PC1 C3B C3C  sing N N 352 
PC1 C3B H3B1 sing N N 353 
PC1 C3B H3B2 sing N N 354 
PC1 C3C C3D  sing N N 355 
PC1 C3C H3C1 sing N N 356 
PC1 C3C H3C2 sing N N 357 
PC1 C3D C3E  sing N N 358 
PC1 C3D H3D1 sing N N 359 
PC1 C3D H3D2 sing N N 360 
PC1 C3E C3F  sing N N 361 
PC1 C3E H3E1 sing N N 362 
PC1 C3E H3E2 sing N N 363 
PC1 C3F C3G  sing N N 364 
PC1 C3F H3F1 sing N N 365 
PC1 C3F H3F2 sing N N 366 
PC1 C3G C3H  sing N N 367 
PC1 C3G H3G1 sing N N 368 
PC1 C3G H3G2 sing N N 369 
PC1 C3H C3I  sing N N 370 
PC1 C3H H3H1 sing N N 371 
PC1 C3H H3H2 sing N N 372 
PC1 C3I H3I1 sing N N 373 
PC1 C3I H3I2 sing N N 374 
PC1 C3I H3I3 sing N N 375 
PHE N   CA   sing N N 376 
PHE N   H    sing N N 377 
PHE N   H2   sing N N 378 
PHE CA  C    sing N N 379 
PHE CA  CB   sing N N 380 
PHE CA  HA   sing N N 381 
PHE C   O    doub N N 382 
PHE C   OXT  sing N N 383 
PHE CB  CG   sing N N 384 
PHE CB  HB2  sing N N 385 
PHE CB  HB3  sing N N 386 
PHE CG  CD1  doub Y N 387 
PHE CG  CD2  sing Y N 388 
PHE CD1 CE1  sing Y N 389 
PHE CD1 HD1  sing N N 390 
PHE CD2 CE2  doub Y N 391 
PHE CD2 HD2  sing N N 392 
PHE CE1 CZ   doub Y N 393 
PHE CE1 HE1  sing N N 394 
PHE CE2 CZ   sing Y N 395 
PHE CE2 HE2  sing N N 396 
PHE CZ  HZ   sing N N 397 
PHE OXT HXT  sing N N 398 
PO4 P   O1   doub N N 399 
PO4 P   O2   sing N N 400 
PO4 P   O3   sing N N 401 
PO4 P   O4   sing N N 402 
PRO N   CA   sing N N 403 
PRO N   CD   sing N N 404 
PRO N   H    sing N N 405 
PRO CA  C    sing N N 406 
PRO CA  CB   sing N N 407 
PRO CA  HA   sing N N 408 
PRO C   O    doub N N 409 
PRO C   OXT  sing N N 410 
PRO CB  CG   sing N N 411 
PRO CB  HB2  sing N N 412 
PRO CB  HB3  sing N N 413 
PRO CG  CD   sing N N 414 
PRO CG  HG2  sing N N 415 
PRO CG  HG3  sing N N 416 
PRO CD  HD2  sing N N 417 
PRO CD  HD3  sing N N 418 
PRO OXT HXT  sing N N 419 
SER N   CA   sing N N 420 
SER N   H    sing N N 421 
SER N   H2   sing N N 422 
SER CA  C    sing N N 423 
SER CA  CB   sing N N 424 
SER CA  HA   sing N N 425 
SER C   O    doub N N 426 
SER C   OXT  sing N N 427 
SER CB  OG   sing N N 428 
SER CB  HB2  sing N N 429 
SER CB  HB3  sing N N 430 
SER OG  HG   sing N N 431 
SER OXT HXT  sing N N 432 
THR N   CA   sing N N 433 
THR N   H    sing N N 434 
THR N   H2   sing N N 435 
THR CA  C    sing N N 436 
THR CA  CB   sing N N 437 
THR CA  HA   sing N N 438 
THR C   O    doub N N 439 
THR C   OXT  sing N N 440 
THR CB  OG1  sing N N 441 
THR CB  CG2  sing N N 442 
THR CB  HB   sing N N 443 
THR OG1 HG1  sing N N 444 
THR CG2 HG21 sing N N 445 
THR CG2 HG22 sing N N 446 
THR CG2 HG23 sing N N 447 
THR OXT HXT  sing N N 448 
TRP N   CA   sing N N 449 
TRP N   H    sing N N 450 
TRP N   H2   sing N N 451 
TRP CA  C    sing N N 452 
TRP CA  CB   sing N N 453 
TRP CA  HA   sing N N 454 
TRP C   O    doub N N 455 
TRP C   OXT  sing N N 456 
TRP CB  CG   sing N N 457 
TRP CB  HB2  sing N N 458 
TRP CB  HB3  sing N N 459 
TRP CG  CD1  doub Y N 460 
TRP CG  CD2  sing Y N 461 
TRP CD1 NE1  sing Y N 462 
TRP CD1 HD1  sing N N 463 
TRP CD2 CE2  doub Y N 464 
TRP CD2 CE3  sing Y N 465 
TRP NE1 CE2  sing Y N 466 
TRP NE1 HE1  sing N N 467 
TRP CE2 CZ2  sing Y N 468 
TRP CE3 CZ3  doub Y N 469 
TRP CE3 HE3  sing N N 470 
TRP CZ2 CH2  doub Y N 471 
TRP CZ2 HZ2  sing N N 472 
TRP CZ3 CH2  sing Y N 473 
TRP CZ3 HZ3  sing N N 474 
TRP CH2 HH2  sing N N 475 
TRP OXT HXT  sing N N 476 
TYR N   CA   sing N N 477 
TYR N   H    sing N N 478 
TYR N   H2   sing N N 479 
TYR CA  C    sing N N 480 
TYR CA  CB   sing N N 481 
TYR CA  HA   sing N N 482 
TYR C   O    doub N N 483 
TYR C   OXT  sing N N 484 
TYR CB  CG   sing N N 485 
TYR CB  HB2  sing N N 486 
TYR CB  HB3  sing N N 487 
TYR CG  CD1  doub Y N 488 
TYR CG  CD2  sing Y N 489 
TYR CD1 CE1  sing Y N 490 
TYR CD1 HD1  sing N N 491 
TYR CD2 CE2  doub Y N 492 
TYR CD2 HD2  sing N N 493 
TYR CE1 CZ   doub Y N 494 
TYR CE1 HE1  sing N N 495 
TYR CE2 CZ   sing Y N 496 
TYR CE2 HE2  sing N N 497 
TYR CZ  OH   sing N N 498 
TYR OH  HH   sing N N 499 
TYR OXT HXT  sing N N 500 
VAL N   CA   sing N N 501 
VAL N   H    sing N N 502 
VAL N   H2   sing N N 503 
VAL CA  C    sing N N 504 
VAL CA  CB   sing N N 505 
VAL CA  HA   sing N N 506 
VAL C   O    doub N N 507 
VAL C   OXT  sing N N 508 
VAL CB  CG1  sing N N 509 
VAL CB  CG2  sing N N 510 
VAL CB  HB   sing N N 511 
VAL CG1 HG11 sing N N 512 
VAL CG1 HG12 sing N N 513 
VAL CG1 HG13 sing N N 514 
VAL CG2 HG21 sing N N 515 
VAL CG2 HG22 sing N N 516 
VAL CG2 HG23 sing N N 517 
VAL OXT HXT  sing N N 518 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-11 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9J52 
_em_admin.last_update        2025-01-15 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'CryoEM structure of human XPR1 in complex with phosphate in state B' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           4.7 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9J52 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA A 1 229 ? 154.996 145.550 124.178 1.00 81.01  ? 229 ALA A N   1 
ATOM   2    C CA  . ALA A 1 229 ? 154.616 145.833 125.556 1.00 75.66  ? 229 ALA A CA  1 
ATOM   3    C C   . ALA A 1 229 ? 153.113 145.672 125.746 1.00 79.56  ? 229 ALA A C   1 
ATOM   4    O O   . ALA A 1 229 ? 152.346 146.580 125.428 1.00 83.90  ? 229 ALA A O   1 
ATOM   5    C CB  . ALA A 1 229 ? 155.054 147.234 125.953 1.00 61.97  ? 229 ALA A CB  1 
ATOM   6    N N   . PRO A 1 230 ? 152.692 144.513 126.252 1.00 75.38  ? 230 PRO A N   1 
ATOM   7    C CA  . PRO A 1 230 ? 151.263 144.297 126.503 1.00 70.25  ? 230 PRO A CA  1 
ATOM   8    C C   . PRO A 1 230 ? 150.739 145.262 127.555 1.00 67.15  ? 230 PRO A C   1 
ATOM   9    O O   . PRO A 1 230 ? 151.462 145.681 128.461 1.00 63.13  ? 230 PRO A O   1 
ATOM   10   C CB  . PRO A 1 230 ? 151.202 142.845 126.994 1.00 64.89  ? 230 PRO A CB  1 
ATOM   11   C CG  . PRO A 1 230 ? 152.482 142.224 126.535 1.00 66.25  ? 230 PRO A CG  1 
ATOM   12   C CD  . PRO A 1 230 ? 153.494 143.323 126.574 1.00 67.44  ? 230 PRO A CD  1 
ATOM   13   N N   . ALA A 1 231 ? 149.460 145.619 127.419 1.00 64.78  ? 231 ALA A N   1 
ATOM   14   C CA  . ALA A 1 231 ? 148.852 146.550 128.363 1.00 62.06  ? 231 ALA A CA  1 
ATOM   15   C C   . ALA A 1 231 ? 148.795 145.958 129.764 1.00 53.87  ? 231 ALA A C   1 
ATOM   16   O O   . ALA A 1 231 ? 149.017 146.665 130.755 1.00 50.54  ? 231 ALA A O   1 
ATOM   17   C CB  . ALA A 1 231 ? 147.456 146.943 127.886 1.00 61.53  ? 231 ALA A CB  1 
ATOM   18   N N   . TRP A 1 232 ? 148.493 144.662 129.868 1.00 49.71  ? 232 TRP A N   1 
ATOM   19   C CA  . TRP A 1 232 ? 148.472 144.023 131.177 1.00 43.54  ? 232 TRP A CA  1 
ATOM   20   C C   . TRP A 1 232 ? 149.843 144.044 131.830 1.00 44.51  ? 232 TRP A C   1 
ATOM   21   O O   . TRP A 1 232 ? 149.940 144.140 133.055 1.00 43.78  ? 232 TRP A O   1 
ATOM   22   C CB  . TRP A 1 232 ? 147.963 142.588 131.061 1.00 45.68  ? 232 TRP A CB  1 
ATOM   23   C CG  . TRP A 1 232 ? 146.481 142.471 131.193 1.00 37.79  ? 232 TRP A CG  1 
ATOM   24   C CD1 . TRP A 1 232 ? 145.586 142.266 130.190 1.00 33.25  ? 232 TRP A CD1 1 
ATOM   25   C CD2 . TRP A 1 232 ? 145.718 142.559 132.400 1.00 36.89  ? 232 TRP A CD2 1 
ATOM   26   N NE1 . TRP A 1 232 ? 144.312 142.218 130.696 1.00 33.83  ? 232 TRP A NE1 1 
ATOM   27   C CE2 . TRP A 1 232 ? 144.368 142.396 132.052 1.00 36.25  ? 232 TRP A CE2 1 
ATOM   28   C CE3 . TRP A 1 232 ? 146.048 142.763 133.742 1.00 39.65  ? 232 TRP A CE3 1 
ATOM   29   C CZ2 . TRP A 1 232 ? 143.346 142.429 132.994 1.00 41.07  ? 232 TRP A CZ2 1 
ATOM   30   C CZ3 . TRP A 1 232 ? 145.032 142.795 134.675 1.00 37.83  ? 232 TRP A CZ3 1 
ATOM   31   C CH2 . TRP A 1 232 ? 143.698 142.631 134.298 1.00 37.40  ? 232 TRP A CH2 1 
ATOM   32   N N   . THR A 1 233 ? 150.912 143.955 131.038 1.00 50.91  ? 233 THR A N   1 
ATOM   33   C CA  . THR A 1 233 ? 152.252 144.036 131.608 1.00 47.96  ? 233 THR A CA  1 
ATOM   34   C C   . THR A 1 233 ? 152.500 145.399 132.236 1.00 48.16  ? 233 THR A C   1 
ATOM   35   O O   . THR A 1 233 ? 153.041 145.488 133.343 1.00 49.06  ? 233 THR A O   1 
ATOM   36   C CB  . THR A 1 233 ? 153.301 143.746 130.539 1.00 49.85  ? 233 THR A CB  1 
ATOM   37   O OG1 . THR A 1 233 ? 153.063 142.450 129.979 1.00 58.06  ? 233 THR A OG1 1 
ATOM   38   C CG2 . THR A 1 233 ? 154.686 143.777 131.144 1.00 48.36  ? 233 THR A CG2 1 
ATOM   39   N N   . THR A 1 234 ? 152.109 146.475 131.548 1.00 48.96  ? 234 THR A N   1 
ATOM   40   C CA  . THR A 1 234 ? 152.275 147.810 132.115 1.00 43.76  ? 234 THR A CA  1 
ATOM   41   C C   . THR A 1 234 ? 151.411 147.988 133.354 1.00 39.72  ? 234 THR A C   1 
ATOM   42   O O   . THR A 1 234 ? 151.842 148.591 134.346 1.00 36.68  ? 234 THR A O   1 
ATOM   43   C CB  . THR A 1 234 ? 151.939 148.870 131.069 1.00 40.86  ? 234 THR A CB  1 
ATOM   44   O OG1 . THR A 1 234 ? 152.815 148.730 129.945 1.00 44.39  ? 234 THR A OG1 1 
ATOM   45   C CG2 . THR A 1 234 ? 152.098 150.255 131.651 1.00 38.57  ? 234 THR A CG2 1 
ATOM   46   N N   . PHE A 1 235 ? 150.186 147.459 133.317 1.00 42.17  ? 235 PHE A N   1 
ATOM   47   C CA  . PHE A 1 235 ? 149.327 147.508 134.493 1.00 40.95  ? 235 PHE A CA  1 
ATOM   48   C C   . PHE A 1 235 ? 149.969 146.787 135.667 1.00 40.16  ? 235 PHE A C   1 
ATOM   49   O O   . PHE A 1 235 ? 149.918 147.271 136.798 1.00 38.98  ? 235 PHE A O   1 
ATOM   50   C CB  . PHE A 1 235 ? 147.958 146.902 134.179 1.00 38.65  ? 235 PHE A CB  1 
ATOM   51   C CG  . PHE A 1 235 ? 147.114 146.658 135.397 1.00 32.95  ? 235 PHE A CG  1 
ATOM   52   C CD1 . PHE A 1 235 ? 146.382 147.680 135.959 1.00 36.12  ? 235 PHE A CD1 1 
ATOM   53   C CD2 . PHE A 1 235 ? 147.055 145.409 135.982 1.00 33.79  ? 235 PHE A CD2 1 
ATOM   54   C CE1 . PHE A 1 235 ? 145.615 147.461 137.082 1.00 39.57  ? 235 PHE A CE1 1 
ATOM   55   C CE2 . PHE A 1 235 ? 146.290 145.189 137.106 1.00 34.37  ? 235 PHE A CE2 1 
ATOM   56   C CZ  . PHE A 1 235 ? 145.569 146.217 137.653 1.00 34.74  ? 235 PHE A CZ  1 
ATOM   57   N N   . ARG A 1 236 ? 150.571 145.623 135.421 1.00 38.10  ? 236 ARG A N   1 
ATOM   58   C CA  . ARG A 1 236 ? 151.213 144.879 136.498 1.00 32.02  ? 236 ARG A CA  1 
ATOM   59   C C   . ARG A 1 236 ? 152.433 145.614 137.028 1.00 36.77  ? 236 ARG A C   1 
ATOM   60   O O   . ARG A 1 236 ? 152.680 145.621 138.238 1.00 41.32  ? 236 ARG A O   1 
ATOM   61   C CB  . ARG A 1 236 ? 151.596 143.481 136.022 1.00 37.51  ? 236 ARG A CB  1 
ATOM   62   C CG  . ARG A 1 236 ? 150.423 142.536 135.891 1.00 41.10  ? 236 ARG A CG  1 
ATOM   63   C CD  . ARG A 1 236 ? 150.878 141.094 135.770 1.00 40.22  ? 236 ARG A CD  1 
ATOM   64   N NE  . ARG A 1 236 ? 151.620 140.854 134.540 1.00 45.23  ? 236 ARG A NE  1 
ATOM   65   C CZ  . ARG A 1 236 ? 151.076 140.411 133.416 1.00 48.71  ? 236 ARG A CZ  1 
ATOM   66   N NH1 . ARG A 1 236 ? 149.787 140.139 133.336 1.00 51.24  ? 236 ARG A NH1 1 
ATOM   67   N NH2 . ARG A 1 236 ? 151.846 140.239 132.347 1.00 50.04  ? 236 ARG A NH2 1 
ATOM   68   N N   . VAL A 1 237 ? 153.210 146.234 136.140 1.00 39.94  ? 237 VAL A N   1 
ATOM   69   C CA  . VAL A 1 237 ? 154.368 147.008 136.578 1.00 36.16  ? 237 VAL A CA  1 
ATOM   70   C C   . VAL A 1 237 ? 153.927 148.139 137.493 1.00 35.88  ? 237 VAL A C   1 
ATOM   71   O O   . VAL A 1 237 ? 154.493 148.346 138.572 1.00 36.06  ? 237 VAL A O   1 
ATOM   72   C CB  . VAL A 1 237 ? 155.145 147.548 135.368 1.00 40.00  ? 237 VAL A CB  1 
ATOM   73   C CG1 . VAL A 1 237 ? 156.176 148.557 135.826 1.00 40.00  ? 237 VAL A CG1 1 
ATOM   74   C CG2 . VAL A 1 237 ? 155.804 146.416 134.614 1.00 44.31  ? 237 VAL A CG2 1 
ATOM   75   N N   . GLY A 1 238 ? 152.892 148.874 137.083 1.00 37.58  ? 238 GLY A N   1 
ATOM   76   C CA  . GLY A 1 238 ? 152.386 149.952 137.917 1.00 40.35  ? 238 GLY A CA  1 
ATOM   77   C C   . GLY A 1 238 ? 151.779 149.463 139.218 1.00 36.51  ? 238 GLY A C   1 
ATOM   78   O O   . GLY A 1 238 ? 151.951 150.087 140.267 1.00 35.63  ? 238 GLY A O   1 
ATOM   79   N N   . LEU A 1 239 ? 151.046 148.353 139.165 1.00 32.21  ? 239 LEU A N   1 
ATOM   80   C CA  . LEU A 1 239 ? 150.450 147.787 140.365 1.00 29.30  ? 239 LEU A CA  1 
ATOM   81   C C   . LEU A 1 239 ? 151.522 147.433 141.381 1.00 29.60  ? 239 LEU A C   1 
ATOM   82   O O   . LEU A 1 239 ? 151.431 147.807 142.556 1.00 32.73  ? 239 LEU A O   1 
ATOM   83   C CB  . LEU A 1 239 ? 149.632 146.550 139.991 1.00 30.14  ? 239 LEU A CB  1 
ATOM   84   C CG  . LEU A 1 239 ? 148.818 145.797 141.040 1.00 25.78  ? 239 LEU A CG  1 
ATOM   85   C CD1 . LEU A 1 239 ? 147.523 146.520 141.326 1.00 31.72  ? 239 LEU A CD1 1 
ATOM   86   C CD2 . LEU A 1 239 ? 148.542 144.387 140.565 1.00 24.59  ? 239 LEU A CD2 1 
ATOM   87   N N   . PHE A 1 240 ? 152.552 146.712 140.940 1.00 33.22  ? 240 PHE A N   1 
ATOM   88   C CA  . PHE A 1 240 ? 153.621 146.323 141.848 1.00 29.42  ? 240 PHE A CA  1 
ATOM   89   C C   . PHE A 1 240 ? 154.399 147.535 142.337 1.00 35.97  ? 240 PHE A C   1 
ATOM   90   O O   . PHE A 1 240 ? 154.807 147.580 143.500 1.00 40.71  ? 240 PHE A O   1 
ATOM   91   C CB  . PHE A 1 240 ? 154.537 145.315 141.167 1.00 28.44  ? 240 PHE A CB  1 
ATOM   92   C CG  . PHE A 1 240 ? 153.870 144.011 140.870 1.00 30.42  ? 240 PHE A CG  1 
ATOM   93   C CD1 . PHE A 1 240 ? 152.857 143.543 141.678 1.00 29.32  ? 240 PHE A CD1 1 
ATOM   94   C CD2 . PHE A 1 240 ? 154.248 143.256 139.783 1.00 37.48  ? 240 PHE A CD2 1 
ATOM   95   C CE1 . PHE A 1 240 ? 152.236 142.344 141.410 1.00 25.91  ? 240 PHE A CE1 1 
ATOM   96   C CE2 . PHE A 1 240 ? 153.628 142.058 139.511 1.00 37.45  ? 240 PHE A CE2 1 
ATOM   97   C CZ  . PHE A 1 240 ? 152.622 141.604 140.326 1.00 28.73  ? 240 PHE A CZ  1 
ATOM   98   N N   . CYS A 1 241 ? 154.592 148.538 141.478 1.00 38.89  ? 241 CYS A N   1 
ATOM   99   C CA  . CYS A 1 241 ? 155.261 149.761 141.908 1.00 39.93  ? 241 CYS A CA  1 
ATOM   100  C C   . CYS A 1 241 ? 154.481 150.458 143.016 1.00 37.65  ? 241 CYS A C   1 
ATOM   101  O O   . CYS A 1 241 ? 155.056 150.874 144.026 1.00 37.87  ? 241 CYS A O   1 
ATOM   102  C CB  . CYS A 1 241 ? 155.449 150.694 140.712 1.00 43.70  ? 241 CYS A CB  1 
ATOM   103  S SG  . CYS A 1 241 ? 156.204 152.285 141.097 1.00 58.60  ? 241 CYS A SG  1 
ATOM   104  N N   . GLY A 1 242 ? 153.165 150.592 142.846 1.00 35.25  ? 242 GLY A N   1 
ATOM   105  C CA  . GLY A 1 242 ? 152.361 151.256 143.860 1.00 36.86  ? 242 GLY A CA  1 
ATOM   106  C C   . GLY A 1 242 ? 152.287 150.476 145.158 1.00 37.44  ? 242 GLY A C   1 
ATOM   107  O O   . GLY A 1 242 ? 152.397 151.051 146.249 1.00 36.47  ? 242 GLY A O   1 
ATOM   108  N N   . ILE A 1 243 ? 152.101 149.158 145.060 1.00 39.08  ? 243 ILE A N   1 
ATOM   109  C CA  . ILE A 1 243 ? 152.080 148.327 146.258 1.00 36.47  ? 243 ILE A CA  1 
ATOM   110  C C   . ILE A 1 243 ? 153.417 148.415 146.978 1.00 37.68  ? 243 ILE A C   1 
ATOM   111  O O   . ILE A 1 243 ? 153.467 148.518 148.206 1.00 42.53  ? 243 ILE A O   1 
ATOM   112  C CB  . ILE A 1 243 ? 151.710 146.875 145.905 1.00 26.78  ? 243 ILE A CB  1 
ATOM   113  C CG1 . ILE A 1 243 ? 150.316 146.807 145.295 1.00 24.88  ? 243 ILE A CG1 1 
ATOM   114  C CG2 . ILE A 1 243 ? 151.711 146.013 147.138 1.00 32.24  ? 243 ILE A CG2 1 
ATOM   115  C CD1 . ILE A 1 243 ? 149.860 145.404 145.001 1.00 19.13  ? 243 ILE A CD1 1 
ATOM   116  N N   . PHE A 1 244 ? 154.520 148.408 146.228 1.00 34.68  ? 244 PHE A N   1 
ATOM   117  C CA  . PHE A 1 244 ? 155.838 148.501 146.841 1.00 34.86  ? 244 PHE A CA  1 
ATOM   118  C C   . PHE A 1 244 ? 156.055 149.856 147.498 1.00 40.27  ? 244 PHE A C   1 
ATOM   119  O O   . PHE A 1 244 ? 156.644 149.938 148.578 1.00 46.78  ? 244 PHE A O   1 
ATOM   120  C CB  . PHE A 1 244 ? 156.910 148.228 145.791 1.00 39.68  ? 244 PHE A CB  1 
ATOM   121  C CG  . PHE A 1 244 ? 158.289 148.135 146.349 1.00 38.92  ? 244 PHE A CG  1 
ATOM   122  C CD1 . PHE A 1 244 ? 158.674 147.034 147.083 1.00 35.98  ? 244 PHE A CD1 1 
ATOM   123  C CD2 . PHE A 1 244 ? 159.207 149.141 146.126 1.00 39.82  ? 244 PHE A CD2 1 
ATOM   124  C CE1 . PHE A 1 244 ? 159.943 146.946 147.592 1.00 40.91  ? 244 PHE A CE1 1 
ATOM   125  C CE2 . PHE A 1 244 ? 160.476 149.057 146.635 1.00 39.93  ? 244 PHE A CE2 1 
ATOM   126  C CZ  . PHE A 1 244 ? 160.846 147.957 147.368 1.00 43.64  ? 244 PHE A CZ  1 
ATOM   127  N N   . ILE A 1 245 ? 155.582 150.933 146.868 1.00 38.82  ? 245 ILE A N   1 
ATOM   128  C CA  . ILE A 1 245 ? 155.728 152.261 147.459 1.00 40.42  ? 245 ILE A CA  1 
ATOM   129  C C   . ILE A 1 245 ? 154.988 152.337 148.788 1.00 43.71  ? 245 ILE A C   1 
ATOM   130  O O   . ILE A 1 245 ? 155.546 152.760 149.811 1.00 45.36  ? 245 ILE A O   1 
ATOM   131  C CB  . ILE A 1 245 ? 155.229 153.338 146.482 1.00 40.82  ? 245 ILE A CB  1 
ATOM   132  C CG1 . ILE A 1 245 ? 156.188 153.481 145.304 1.00 39.90  ? 245 ILE A CG1 1 
ATOM   133  C CG2 . ILE A 1 245 ? 155.058 154.665 147.195 1.00 40.62  ? 245 ILE A CG2 1 
ATOM   134  C CD1 . ILE A 1 245 ? 155.636 154.321 144.190 1.00 38.66  ? 245 ILE A CD1 1 
ATOM   135  N N   . VAL A 1 246 ? 153.719 151.920 148.797 1.00 44.90  ? 246 VAL A N   1 
ATOM   136  C CA  . VAL A 1 246 ? 152.934 152.030 150.024 1.00 45.85  ? 246 VAL A CA  1 
ATOM   137  C C   . VAL A 1 246 ? 153.465 151.077 151.090 1.00 42.55  ? 246 VAL A C   1 
ATOM   138  O O   . VAL A 1 246 ? 153.499 151.414 152.279 1.00 42.89  ? 246 VAL A O   1 
ATOM   139  C CB  . VAL A 1 246 ? 151.441 151.798 149.740 1.00 39.86  ? 246 VAL A CB  1 
ATOM   140  C CG1 . VAL A 1 246 ? 150.633 152.045 150.994 1.00 35.39  ? 246 VAL A CG1 1 
ATOM   141  C CG2 . VAL A 1 246 ? 150.974 152.721 148.637 1.00 42.01  ? 246 VAL A CG2 1 
ATOM   142  N N   . LEU A 1 247 ? 153.905 149.883 150.688 1.00 41.11  ? 247 LEU A N   1 
ATOM   143  C CA  . LEU A 1 247 ? 154.452 148.941 151.654 1.00 43.51  ? 247 LEU A CA  1 
ATOM   144  C C   . LEU A 1 247 ? 155.768 149.439 152.233 1.00 50.93  ? 247 LEU A C   1 
ATOM   145  O O   . LEU A 1 247 ? 156.046 149.223 153.413 1.00 60.57  ? 247 LEU A O   1 
ATOM   146  C CB  . LEU A 1 247 ? 154.631 147.567 151.011 1.00 39.30  ? 247 LEU A CB  1 
ATOM   147  C CG  . LEU A 1 247 ? 153.363 146.743 150.793 1.00 29.82  ? 247 LEU A CG  1 
ATOM   148  C CD1 . LEU A 1 247 ? 153.705 145.384 150.225 1.00 36.23  ? 247 LEU A CD1 1 
ATOM   149  C CD2 . LEU A 1 247 ? 152.592 146.599 152.080 1.00 37.07  ? 247 LEU A CD2 1 
ATOM   150  N N   . ASN A 1 248 ? 156.595 150.107 151.428 1.00 47.25  ? 248 ASN A N   1 
ATOM   151  C CA  . ASN A 1 248 ? 157.843 150.646 151.957 1.00 48.96  ? 248 ASN A CA  1 
ATOM   152  C C   . ASN A 1 248 ? 157.585 151.808 152.906 1.00 55.92  ? 248 ASN A C   1 
ATOM   153  O O   . ASN A 1 248 ? 158.276 151.949 153.923 1.00 57.81  ? 248 ASN A O   1 
ATOM   154  C CB  . ASN A 1 248 ? 158.760 151.074 150.816 1.00 46.55  ? 248 ASN A CB  1 
ATOM   155  C CG  . ASN A 1 248 ? 160.054 150.294 150.794 1.00 54.37  ? 248 ASN A CG  1 
ATOM   156  O OD1 . ASN A 1 248 ? 160.076 149.103 151.096 1.00 53.18  ? 248 ASN A OD1 1 
ATOM   157  N ND2 . ASN A 1 248 ? 161.145 150.963 150.450 1.00 66.74  ? 248 ASN A ND2 1 
ATOM   158  N N   . ILE A 1 249 ? 156.603 152.656 152.593 1.00 53.40  ? 249 ILE A N   1 
ATOM   159  C CA  . ILE A 1 249 ? 156.238 153.713 153.533 1.00 53.73  ? 249 ILE A CA  1 
ATOM   160  C C   . ILE A 1 249 ? 155.733 153.104 154.834 1.00 58.00  ? 249 ILE A C   1 
ATOM   161  O O   . ILE A 1 249 ? 156.096 153.547 155.930 1.00 58.65  ? 249 ILE A O   1 
ATOM   162  C CB  . ILE A 1 249 ? 155.200 154.662 152.910 1.00 48.71  ? 249 ILE A CB  1 
ATOM   163  C CG1 . ILE A 1 249 ? 155.774 155.330 151.665 1.00 45.91  ? 249 ILE A CG1 1 
ATOM   164  C CG2 . ILE A 1 249 ? 154.780 155.717 153.912 1.00 49.72  ? 249 ILE A CG2 1 
ATOM   165  C CD1 . ILE A 1 249 ? 154.873 156.377 151.066 1.00 43.78  ? 249 ILE A CD1 1 
ATOM   166  N N   . THR A 1 250 ? 154.901 152.065 154.733 1.00 56.71  ? 250 THR A N   1 
ATOM   167  C CA  . THR A 1 250 ? 154.428 151.376 155.927 1.00 58.44  ? 250 THR A CA  1 
ATOM   168  C C   . THR A 1 250 ? 155.590 150.770 156.701 1.00 62.04  ? 250 THR A C   1 
ATOM   169  O O   . THR A 1 250 ? 155.594 150.771 157.935 1.00 68.50  ? 250 THR A O   1 
ATOM   170  C CB  . THR A 1 250 ? 153.421 150.295 155.535 1.00 55.45  ? 250 THR A CB  1 
ATOM   171  O OG1 . THR A 1 250 ? 152.475 150.839 154.609 1.00 55.79  ? 250 THR A OG1 1 
ATOM   172  C CG2 . THR A 1 250 ? 152.681 149.784 156.756 1.00 58.79  ? 250 THR A CG2 1 
ATOM   173  N N   . LEU A 1 251 ? 156.590 150.252 155.988 1.00 60.34  ? 251 LEU A N   1 
ATOM   174  C CA  . LEU A 1 251 ? 157.739 149.639 156.640 1.00 63.26  ? 251 LEU A CA  1 
ATOM   175  C C   . LEU A 1 251 ? 158.559 150.667 157.402 1.00 67.69  ? 251 LEU A C   1 
ATOM   176  O O   . LEU A 1 251 ? 158.987 150.412 158.531 1.00 77.45  ? 251 LEU A O   1 
ATOM   177  C CB  . LEU A 1 251 ? 158.603 148.927 155.603 1.00 60.33  ? 251 LEU A CB  1 
ATOM   178  C CG  . LEU A 1 251 ? 159.816 148.174 156.139 1.00 58.38  ? 251 LEU A CG  1 
ATOM   179  C CD1 . LEU A 1 251 ? 159.379 147.056 157.056 1.00 61.82  ? 251 LEU A CD1 1 
ATOM   180  C CD2 . LEU A 1 251 ? 160.632 147.633 154.989 1.00 63.83  ? 251 LEU A CD2 1 
ATOM   181  N N   . VAL A 1 252 ? 158.793 151.837 156.805 1.00 65.43  ? 252 VAL A N   1 
ATOM   182  C CA  . VAL A 1 252 ? 159.566 152.854 157.514 1.00 70.80  ? 252 VAL A CA  1 
ATOM   183  C C   . VAL A 1 252 ? 158.775 153.389 158.705 1.00 77.15  ? 252 VAL A C   1 
ATOM   184  O O   . VAL A 1 252 ? 159.343 153.655 159.771 1.00 79.71  ? 252 VAL A O   1 
ATOM   185  C CB  . VAL A 1 252 ? 160.025 153.980 156.566 1.00 65.77  ? 252 VAL A CB  1 
ATOM   186  C CG1 . VAL A 1 252 ? 160.729 153.403 155.356 1.00 64.84  ? 252 VAL A CG1 1 
ATOM   187  C CG2 . VAL A 1 252 ? 158.880 154.874 156.149 1.00 69.13  ? 252 VAL A CG2 1 
ATOM   188  N N   . LEU A 1 253 ? 157.453 153.526 158.561 1.00 76.07  ? 253 LEU A N   1 
ATOM   189  C CA  . LEU A 1 253 ? 156.639 153.957 159.696 1.00 77.64  ? 253 LEU A CA  1 
ATOM   190  C C   . LEU A 1 253 ? 156.667 152.929 160.822 1.00 78.81  ? 253 LEU A C   1 
ATOM   191  O O   . LEU A 1 253 ? 156.768 153.291 162.000 1.00 81.13  ? 253 LEU A O   1 
ATOM   192  C CB  . LEU A 1 253 ? 155.205 154.224 159.243 1.00 73.54  ? 253 LEU A CB  1 
ATOM   193  C CG  . LEU A 1 253 ? 155.059 155.358 158.228 1.00 70.81  ? 253 LEU A CG  1 
ATOM   194  C CD1 . LEU A 1 253 ? 153.625 155.484 157.755 1.00 70.42  ? 253 LEU A CD1 1 
ATOM   195  C CD2 . LEU A 1 253 ? 155.550 156.669 158.812 1.00 77.45  ? 253 LEU A CD2 1 
ATOM   196  N N   . ALA A 1 254 ? 156.579 151.642 160.481 1.00 76.17  ? 254 ALA A N   1 
ATOM   197  C CA  . ALA A 1 254 ? 156.642 150.595 161.494 1.00 80.61  ? 254 ALA A CA  1 
ATOM   198  C C   . ALA A 1 254 ? 158.004 150.566 162.174 1.00 86.89  ? 254 ALA A C   1 
ATOM   199  O O   . ALA A 1 254 ? 158.095 150.381 163.393 1.00 92.54  ? 254 ALA A O   1 
ATOM   200  C CB  . ALA A 1 254 ? 156.326 149.237 160.868 1.00 72.35  ? 254 ALA A CB  1 
ATOM   201  N N   . ALA A 1 255 ? 159.077 150.742 161.400 1.00 84.25  ? 255 ALA A N   1 
ATOM   202  C CA  . ALA A 1 255 ? 160.410 150.779 161.988 1.00 85.57  ? 255 ALA A CA  1 
ATOM   203  C C   . ALA A 1 255 ? 160.556 151.959 162.936 1.00 92.98  ? 255 ALA A C   1 
ATOM   204  O O   . ALA A 1 255 ? 161.180 151.839 163.996 1.00 104.06 ? 255 ALA A O   1 
ATOM   205  C CB  . ALA A 1 255 ? 161.470 150.837 160.890 1.00 81.96  ? 255 ALA A CB  1 
ATOM   206  N N   . VAL A 1 256 ? 159.992 153.112 162.572 1.00 85.89  ? 256 VAL A N   1 
ATOM   207  C CA  . VAL A 1 256 ? 160.057 154.267 163.461 1.00 87.18  ? 256 VAL A CA  1 
ATOM   208  C C   . VAL A 1 256 ? 159.252 154.018 164.731 1.00 91.40  ? 256 VAL A C   1 
ATOM   209  O O   . VAL A 1 256 ? 159.708 154.325 165.839 1.00 94.65  ? 256 VAL A O   1 
ATOM   210  C CB  . VAL A 1 256 ? 159.582 155.534 162.729 1.00 87.21  ? 256 VAL A CB  1 
ATOM   211  C CG1 . VAL A 1 256 ? 159.433 156.685 163.708 1.00 87.44  ? 256 VAL A CG1 1 
ATOM   212  C CG2 . VAL A 1 256 ? 160.561 155.902 161.632 1.00 85.80  ? 256 VAL A CG2 1 
ATOM   213  N N   . PHE A 1 257 ? 158.054 153.447 164.601 1.00 89.03  ? 257 PHE A N   1 
ATOM   214  C CA  . PHE A 1 257 ? 157.133 153.323 165.727 1.00 90.42  ? 257 PHE A CA  1 
ATOM   215  C C   . PHE A 1 257 ? 157.156 151.937 166.364 1.00 94.28  ? 257 PHE A C   1 
ATOM   216  O O   . PHE A 1 257 ? 157.438 151.803 167.558 1.00 100.77 ? 257 PHE A O   1 
ATOM   217  C CB  . PHE A 1 257 ? 155.709 153.672 165.276 1.00 88.68  ? 257 PHE A CB  1 
ATOM   218  C CG  . PHE A 1 257 ? 155.502 155.132 165.000 1.00 92.66  ? 257 PHE A CG  1 
ATOM   219  C CD1 . PHE A 1 257 ? 155.139 155.996 166.019 1.00 91.56  ? 257 PHE A CD1 1 
ATOM   220  C CD2 . PHE A 1 257 ? 155.669 155.643 163.725 1.00 92.95  ? 257 PHE A CD2 1 
ATOM   221  C CE1 . PHE A 1 257 ? 154.948 157.339 165.771 1.00 90.61  ? 257 PHE A CE1 1 
ATOM   222  C CE2 . PHE A 1 257 ? 155.480 156.986 163.470 1.00 88.61  ? 257 PHE A CE2 1 
ATOM   223  C CZ  . PHE A 1 257 ? 155.119 157.835 164.495 1.00 88.50  ? 257 PHE A CZ  1 
ATOM   224  N N   . LYS A 1 258 ? 156.865 150.897 165.587 1.00 90.77  ? 258 LYS A N   1 
ATOM   225  C CA  . LYS A 1 258 ? 156.633 149.578 166.161 1.00 93.41  ? 258 LYS A CA  1 
ATOM   226  C C   . LYS A 1 258 ? 157.913 148.841 166.532 1.00 99.74  ? 258 LYS A C   1 
ATOM   227  O O   . LYS A 1 258 ? 157.838 147.824 167.229 1.00 104.57 ? 258 LYS A O   1 
ATOM   228  C CB  . LYS A 1 258 ? 155.818 148.724 165.188 1.00 93.93  ? 258 LYS A CB  1 
ATOM   229  C CG  . LYS A 1 258 ? 154.453 149.302 164.857 1.00 97.50  ? 258 LYS A CG  1 
ATOM   230  C CD  . LYS A 1 258 ? 153.568 149.382 166.091 1.00 97.23  ? 258 LYS A CD  1 
ATOM   231  C CE  . LYS A 1 258 ? 152.182 149.898 165.744 1.00 92.40  ? 258 LYS A CE  1 
ATOM   232  N NZ  . LYS A 1 258 ? 151.240 149.758 166.887 1.00 91.90  ? 258 LYS A NZ  1 
ATOM   233  N N   . LEU A 1 259 ? 159.074 149.317 166.094 1.00 102.31 ? 259 LEU A N   1 
ATOM   234  C CA  . LEU A 1 259 ? 160.331 148.628 166.347 1.00 109.88 ? 259 LEU A CA  1 
ATOM   235  C C   . LEU A 1 259 ? 160.901 149.064 167.690 1.00 117.73 ? 259 LEU A C   1 
ATOM   236  O O   . LEU A 1 259 ? 161.015 150.263 167.966 1.00 117.70 ? 259 LEU A O   1 
ATOM   237  C CB  . LEU A 1 259 ? 161.333 148.906 165.226 1.00 104.61 ? 259 LEU A CB  1 
ATOM   238  C CG  . LEU A 1 259 ? 162.600 148.048 165.211 1.00 112.29 ? 259 LEU A CG  1 
ATOM   239  C CD1 . LEU A 1 259 ? 162.252 146.576 165.054 1.00 111.24 ? 259 LEU A CD1 1 
ATOM   240  C CD2 . LEU A 1 259 ? 163.539 148.501 164.106 1.00 110.44 ? 259 LEU A CD2 1 
ATOM   241  N N   . GLU A 1 260 ? 161.246 148.084 168.529 1.00 122.44 ? 260 GLU A N   1 
ATOM   242  C CA  . GLU A 1 260 ? 161.803 148.387 169.843 1.00 126.38 ? 260 GLU A CA  1 
ATOM   243  C C   . GLU A 1 260 ? 163.265 148.808 169.768 1.00 129.17 ? 260 GLU A C   1 
ATOM   244  O O   . GLU A 1 260 ? 163.729 149.564 170.628 1.00 129.63 ? 260 GLU A O   1 
ATOM   245  C CB  . GLU A 1 260 ? 161.648 147.180 170.769 1.00 130.14 ? 260 GLU A CB  1 
ATOM   246  C CG  . GLU A 1 260 ? 160.214 146.695 170.919 1.00 128.84 ? 260 GLU A CG  1 
ATOM   247  C CD  . GLU A 1 260 ? 159.295 147.744 171.516 1.00 129.00 ? 260 GLU A CD  1 
ATOM   248  O OE1 . GLU A 1 260 ? 159.787 148.623 172.255 1.00 127.91 ? 260 GLU A OE1 1 
ATOM   249  O OE2 . GLU A 1 260 ? 158.077 147.691 171.245 1.00 129.88 ? 260 GLU A OE2 1 
ATOM   250  N N   . THR A 1 261 ? 163.999 148.326 168.766 1.00 129.31 ? 261 THR A N   1 
ATOM   251  C CA  . THR A 1 261 ? 165.396 148.670 168.504 1.00 131.87 ? 261 THR A CA  1 
ATOM   252  C C   . THR A 1 261 ? 166.329 148.308 169.654 1.00 134.94 ? 261 THR A C   1 
ATOM   253  O O   . THR A 1 261 ? 167.438 148.849 169.736 1.00 135.34 ? 261 THR A O   1 
ATOM   254  C CB  . THR A 1 261 ? 165.564 150.159 168.162 1.00 131.29 ? 261 THR A CB  1 
ATOM   255  O OG1 . THR A 1 261 ? 165.255 150.959 169.310 1.00 135.23 ? 261 THR A OG1 1 
ATOM   256  C CG2 . THR A 1 261 ? 164.652 150.555 167.011 1.00 123.34 ? 261 THR A CG2 1 
ATOM   257  N N   . ASP A 1 262 ? 165.917 147.407 170.547 1.00 136.70 ? 262 ASP A N   1 
ATOM   258  C CA  . ASP A 1 262 ? 166.737 147.005 171.683 1.00 137.62 ? 262 ASP A CA  1 
ATOM   259  C C   . ASP A 1 262 ? 167.091 145.522 171.649 1.00 138.04 ? 262 ASP A C   1 
ATOM   260  O O   . ASP A 1 262 ? 167.430 144.946 172.688 1.00 137.36 ? 262 ASP A O   1 
ATOM   261  C CB  . ASP A 1 262 ? 166.036 147.353 172.997 1.00 137.09 ? 262 ASP A CB  1 
ATOM   262  C CG  . ASP A 1 262 ? 164.686 146.672 173.142 1.00 135.89 ? 262 ASP A CG  1 
ATOM   263  O OD1 . ASP A 1 262 ? 164.253 145.982 172.197 1.00 134.73 ? 262 ASP A OD1 1 
ATOM   264  O OD2 . ASP A 1 262 ? 164.056 146.829 174.208 1.00 135.15 ? 262 ASP A OD2 1 
ATOM   265  N N   . ARG A 1 263 ? 167.014 144.890 170.480 1.00 135.46 ? 263 ARG A N   1 
ATOM   266  C CA  . ARG A 1 263 ? 167.284 143.461 170.358 1.00 132.78 ? 263 ARG A CA  1 
ATOM   267  C C   . ARG A 1 263 ? 168.169 143.179 169.153 1.00 127.66 ? 263 ARG A C   1 
ATOM   268  O O   . ARG A 1 263 ? 168.000 142.167 168.466 1.00 127.19 ? 263 ARG A O   1 
ATOM   269  C CB  . ARG A 1 263 ? 165.987 142.658 170.270 1.00 134.15 ? 263 ARG A CB  1 
ATOM   270  C CG  . ARG A 1 263 ? 165.181 142.645 171.557 1.00 135.67 ? 263 ARG A CG  1 
ATOM   271  C CD  . ARG A 1 263 ? 163.889 141.863 171.397 1.00 135.46 ? 263 ARG A CD  1 
ATOM   272  N NE  . ARG A 1 263 ? 163.021 142.446 170.382 1.00 138.66 ? 263 ARG A NE  1 
ATOM   273  C CZ  . ARG A 1 263 ? 162.204 143.469 170.594 1.00 139.46 ? 263 ARG A CZ  1 
ATOM   274  N NH1 . ARG A 1 263 ? 162.129 144.060 171.775 1.00 135.73 ? 263 ARG A NH1 1 
ATOM   275  N NH2 . ARG A 1 263 ? 161.444 143.910 169.595 1.00 140.69 ? 263 ARG A NH2 1 
ATOM   276  N N   . SER A 1 264 ? 169.126 144.070 168.883 1.00 125.89 ? 264 SER A N   1 
ATOM   277  C CA  . SER A 1 264 ? 170.140 143.866 167.847 1.00 120.54 ? 264 SER A CA  1 
ATOM   278  C C   . SER A 1 264 ? 169.487 143.631 166.481 1.00 113.43 ? 264 SER A C   1 
ATOM   279  O O   . SER A 1 264 ? 169.493 142.531 165.931 1.00 114.02 ? 264 SER A O   1 
ATOM   280  C CB  . SER A 1 264 ? 171.082 142.715 168.220 1.00 120.43 ? 264 SER A CB  1 
ATOM   281  O OG  . SER A 1 264 ? 171.853 143.037 169.364 1.00 124.02 ? 264 SER A OG  1 
ATOM   282  N N   . ILE A 1 265 ? 168.874 144.700 165.968 1.00 109.60 ? 265 ILE A N   1 
ATOM   283  C CA  . ILE A 1 265 ? 168.245 144.641 164.654 1.00 106.81 ? 265 ILE A CA  1 
ATOM   284  C C   . ILE A 1 265 ? 169.243 144.434 163.526 1.00 102.81 ? 265 ILE A C   1 
ATOM   285  O O   . ILE A 1 265 ? 168.829 144.155 162.396 1.00 99.01  ? 265 ILE A O   1 
ATOM   286  C CB  . ILE A 1 265 ? 167.443 145.926 164.371 1.00 108.13 ? 265 ILE A CB  1 
ATOM   287  C CG1 . ILE A 1 265 ? 168.394 147.091 164.098 1.00 102.81 ? 265 ILE A CG1 1 
ATOM   288  C CG2 . ILE A 1 265 ? 166.528 146.251 165.539 1.00 113.87 ? 265 ILE A CG2 1 
ATOM   289  C CD1 . ILE A 1 265 ? 167.696 148.365 163.691 1.00 97.86  ? 265 ILE A CD1 1 
ATOM   290  N N   . TRP A 1 266 ? 170.541 144.570 163.797 1.00 103.28 ? 266 TRP A N   1 
ATOM   291  C CA  . TRP A 1 266 ? 171.535 144.466 162.731 1.00 101.23 ? 266 TRP A CA  1 
ATOM   292  C C   . TRP A 1 266 ? 171.527 143.124 162.006 1.00 95.01  ? 266 TRP A C   1 
ATOM   293  O O   . TRP A 1 266 ? 171.681 143.129 160.773 1.00 92.97  ? 266 TRP A O   1 
ATOM   294  C CB  . TRP A 1 266 ? 172.931 144.780 163.286 1.00 103.43 ? 266 TRP A CB  1 
ATOM   295  C CG  . TRP A 1 266 ? 173.156 146.236 163.526 1.00 105.82 ? 266 TRP A CG  1 
ATOM   296  C CD1 . TRP A 1 266 ? 172.205 147.208 163.610 1.00 104.95 ? 266 TRP A CD1 1 
ATOM   297  C CD2 . TRP A 1 266 ? 174.417 146.891 163.697 1.00 111.22 ? 266 TRP A CD2 1 
ATOM   298  N NE1 . TRP A 1 266 ? 172.793 148.428 163.832 1.00 109.44 ? 266 TRP A NE1 1 
ATOM   299  C CE2 . TRP A 1 266 ? 174.152 148.261 163.888 1.00 114.76 ? 266 TRP A CE2 1 
ATOM   300  C CE3 . TRP A 1 266 ? 175.744 146.452 163.710 1.00 109.93 ? 266 TRP A CE3 1 
ATOM   301  C CZ2 . TRP A 1 266 ? 175.164 149.196 164.090 1.00 115.90 ? 266 TRP A CZ2 1 
ATOM   302  C CZ3 . TRP A 1 266 ? 176.748 147.382 163.910 1.00 111.81 ? 266 TRP A CZ3 1 
ATOM   303  C CH2 . TRP A 1 266 ? 176.452 148.738 164.098 1.00 114.85 ? 266 TRP A CH2 1 
ATOM   304  N N   . PRO A 1 267 ? 171.401 141.968 162.667 1.00 95.61  ? 267 PRO A N   1 
ATOM   305  C CA  . PRO A 1 267 ? 171.240 140.723 161.900 1.00 93.04  ? 267 PRO A CA  1 
ATOM   306  C C   . PRO A 1 267 ? 170.056 140.739 160.954 1.00 88.11  ? 267 PRO A C   1 
ATOM   307  O O   . PRO A 1 267 ? 170.144 140.159 159.866 1.00 84.60  ? 267 PRO A O   1 
ATOM   308  C CB  . PRO A 1 267 ? 171.076 139.665 162.995 1.00 95.03  ? 267 PRO A CB  1 
ATOM   309  C CG  . PRO A 1 267 ? 171.884 140.186 164.107 1.00 101.35 ? 267 PRO A CG  1 
ATOM   310  C CD  . PRO A 1 267 ? 171.716 141.683 164.078 1.00 101.75 ? 267 PRO A CD  1 
ATOM   311  N N   . LEU A 1 268 ? 168.950 141.387 161.323 1.00 87.90  ? 268 LEU A N   1 
ATOM   312  C CA  . LEU A 1 268 ? 167.817 141.476 160.407 1.00 84.61  ? 268 LEU A CA  1 
ATOM   313  C C   . LEU A 1 268 ? 168.197 142.226 159.136 1.00 82.33  ? 268 LEU A C   1 
ATOM   314  O O   . LEU A 1 268 ? 167.860 141.799 158.022 1.00 75.22  ? 268 LEU A O   1 
ATOM   315  C CB  . LEU A 1 268 ? 166.640 142.161 161.101 1.00 77.22  ? 268 LEU A CB  1 
ATOM   316  C CG  . LEU A 1 268 ? 165.275 141.902 160.472 1.00 72.57  ? 268 LEU A CG  1 
ATOM   317  C CD1 . LEU A 1 268 ? 164.996 140.416 160.514 1.00 68.25  ? 268 LEU A CD1 1 
ATOM   318  C CD2 . LEU A 1 268 ? 164.190 142.676 161.194 1.00 75.75  ? 268 LEU A CD2 1 
ATOM   319  N N   . ILE A 1 269 ? 168.908 143.344 159.289 1.00 83.81  ? 269 ILE A N   1 
ATOM   320  C CA  . ILE A 1 269 ? 169.359 144.107 158.132 1.00 77.67  ? 269 ILE A CA  1 
ATOM   321  C C   . ILE A 1 269 ? 170.339 143.286 157.307 1.00 79.28  ? 269 ILE A C   1 
ATOM   322  O O   . ILE A 1 269 ? 170.280 143.277 156.074 1.00 77.21  ? 269 ILE A O   1 
ATOM   323  C CB  . ILE A 1 269 ? 169.977 145.441 158.582 1.00 76.38  ? 269 ILE A CB  1 
ATOM   324  C CG1 . ILE A 1 269 ? 169.005 146.189 159.494 1.00 80.76  ? 269 ILE A CG1 1 
ATOM   325  C CG2 . ILE A 1 269 ? 170.337 146.289 157.379 1.00 80.44  ? 269 ILE A CG2 1 
ATOM   326  C CD1 . ILE A 1 269 ? 167.691 146.523 158.835 1.00 83.03  ? 269 ILE A CD1 1 
ATOM   327  N N   . ARG A 1 270 ? 171.260 142.590 157.973 1.00 84.13  ? 270 ARG A N   1 
ATOM   328  C CA  . ARG A 1 270 ? 172.242 141.775 157.270 1.00 82.30  ? 270 ARG A CA  1 
ATOM   329  C C   . ARG A 1 270 ? 171.621 140.578 156.569 1.00 79.37  ? 270 ARG A C   1 
ATOM   330  O O   . ARG A 1 270 ? 172.232 140.045 155.640 1.00 81.63  ? 270 ARG A O   1 
ATOM   331  C CB  . ARG A 1 270 ? 173.327 141.307 158.240 1.00 85.93  ? 270 ARG A CB  1 
ATOM   332  C CG  . ARG A 1 270 ? 174.353 142.381 158.558 1.00 87.85  ? 270 ARG A CG  1 
ATOM   333  C CD  . ARG A 1 270 ? 175.407 141.890 159.532 1.00 96.71  ? 270 ARG A CD  1 
ATOM   334  N NE  . ARG A 1 270 ? 174.895 141.814 160.894 1.00 99.85  ? 270 ARG A NE  1 
ATOM   335  C CZ  . ARG A 1 270 ? 175.624 141.479 161.950 1.00 98.59  ? 270 ARG A CZ  1 
ATOM   336  N NH1 . ARG A 1 270 ? 176.907 141.181 161.838 1.00 99.78  ? 270 ARG A NH1 1 
ATOM   337  N NH2 . ARG A 1 270 ? 175.049 141.440 163.149 1.00 95.36  ? 270 ARG A NH2 1 
ATOM   338  N N   . ILE A 1 271 ? 170.441 140.140 156.992 1.00 73.68  ? 271 ILE A N   1 
ATOM   339  C CA  . ILE A 1 271 ? 169.757 139.055 156.298 1.00 72.89  ? 271 ILE A CA  1 
ATOM   340  C C   . ILE A 1 271 ? 168.936 139.574 155.125 1.00 71.31  ? 271 ILE A C   1 
ATOM   341  O O   . ILE A 1 271 ? 168.916 138.959 154.057 1.00 70.57  ? 271 ILE A O   1 
ATOM   342  C CB  . ILE A 1 271 ? 168.888 138.261 157.289 1.00 76.39  ? 271 ILE A CB  1 
ATOM   343  C CG1 . ILE A 1 271 ? 169.771 137.517 158.288 1.00 82.57  ? 271 ILE A CG1 1 
ATOM   344  C CG2 . ILE A 1 271 ? 168.006 137.275 156.552 1.00 76.44  ? 271 ILE A CG2 1 
ATOM   345  C CD1 . ILE A 1 271 ? 168.997 136.849 159.397 1.00 89.19  ? 271 ILE A CD1 1 
ATOM   346  N N   . TYR A 1 272 ? 168.245 140.704 155.289 1.00 68.34  ? 272 TYR A N   1 
ATOM   347  C CA  . TYR A 1 272 ? 167.424 141.220 154.197 1.00 64.73  ? 272 TYR A CA  1 
ATOM   348  C C   . TYR A 1 272 ? 168.210 142.050 153.188 1.00 61.52  ? 272 TYR A C   1 
ATOM   349  O O   . TYR A 1 272 ? 167.659 142.408 152.136 1.00 62.82  ? 272 TYR A O   1 
ATOM   350  C CB  . TYR A 1 272 ? 166.264 142.042 154.757 1.00 63.03  ? 272 TYR A CB  1 
ATOM   351  C CG  . TYR A 1 272 ? 165.147 141.191 155.314 1.00 57.00  ? 272 TYR A CG  1 
ATOM   352  C CD1 . TYR A 1 272 ? 164.203 140.624 154.475 1.00 53.42  ? 272 TYR A CD1 1 
ATOM   353  C CD2 . TYR A 1 272 ? 165.042 140.948 156.673 1.00 59.82  ? 272 TYR A CD2 1 
ATOM   354  C CE1 . TYR A 1 272 ? 163.190 139.847 154.970 1.00 58.28  ? 272 TYR A CE1 1 
ATOM   355  C CE2 . TYR A 1 272 ? 164.027 140.172 157.177 1.00 57.77  ? 272 TYR A CE2 1 
ATOM   356  C CZ  . TYR A 1 272 ? 163.105 139.623 156.320 1.00 60.14  ? 272 TYR A CZ  1 
ATOM   357  O OH  . TYR A 1 272 ? 162.085 138.846 156.813 1.00 65.60  ? 272 TYR A OH  1 
ATOM   358  N N   . ARG A 1 273 ? 169.478 142.349 153.473 1.00 58.89  ? 273 ARG A N   1 
ATOM   359  C CA  . ARG A 1 273 ? 170.266 143.176 152.572 1.00 57.58  ? 273 ARG A CA  1 
ATOM   360  C C   . ARG A 1 273 ? 170.482 142.492 151.231 1.00 60.38  ? 273 ARG A C   1 
ATOM   361  O O   . ARG A 1 273 ? 170.472 143.151 150.187 1.00 59.08  ? 273 ARG A O   1 
ATOM   362  C CB  . ARG A 1 273 ? 171.601 143.519 153.228 1.00 66.16  ? 273 ARG A CB  1 
ATOM   363  C CG  . ARG A 1 273 ? 172.481 144.454 152.427 1.00 67.82  ? 273 ARG A CG  1 
ATOM   364  C CD  . ARG A 1 273 ? 173.655 144.921 153.268 1.00 72.59  ? 273 ARG A CD  1 
ATOM   365  N NE  . ARG A 1 273 ? 174.391 143.799 153.837 1.00 74.38  ? 273 ARG A NE  1 
ATOM   366  C CZ  . ARG A 1 273 ? 175.358 143.912 154.735 1.00 79.44  ? 273 ARG A CZ  1 
ATOM   367  N NH1 . ARG A 1 273 ? 175.724 145.090 155.212 1.00 80.27  ? 273 ARG A NH1 1 
ATOM   368  N NH2 . ARG A 1 273 ? 175.972 142.816 155.168 1.00 83.14  ? 273 ARG A NH2 1 
ATOM   369  N N   . GLY A 1 274 ? 170.696 141.176 151.237 1.00 64.68  ? 274 GLY A N   1 
ATOM   370  C CA  . GLY A 1 274 ? 170.887 140.470 149.979 1.00 61.71  ? 274 GLY A CA  1 
ATOM   371  C C   . GLY A 1 274 ? 169.684 140.586 149.065 1.00 57.95  ? 274 GLY A C   1 
ATOM   372  O O   . GLY A 1 274 ? 169.816 140.880 147.873 1.00 55.78  ? 274 GLY A O   1 
ATOM   373  N N   . GLY A 1 275 ? 168.490 140.377 149.619 1.00 58.86  ? 275 GLY A N   1 
ATOM   374  C CA  . GLY A 1 275 ? 167.285 140.521 148.822 1.00 58.77  ? 275 GLY A CA  1 
ATOM   375  C C   . GLY A 1 275 ? 167.071 141.941 148.338 1.00 54.03  ? 275 GLY A C   1 
ATOM   376  O O   . GLY A 1 275 ? 166.679 142.160 147.188 1.00 52.88  ? 275 GLY A O   1 
ATOM   377  N N   . PHE A 1 276 ? 167.320 142.927 149.207 1.00 53.54  ? 276 PHE A N   1 
ATOM   378  C CA  . PHE A 1 276 ? 167.159 144.313 148.779 1.00 48.66  ? 276 PHE A CA  1 
ATOM   379  C C   . PHE A 1 276 ? 168.111 144.650 147.644 1.00 49.98  ? 276 PHE A C   1 
ATOM   380  O O   . PHE A 1 276 ? 167.723 145.312 146.674 1.00 55.08  ? 276 PHE A O   1 
ATOM   381  C CB  . PHE A 1 276 ? 167.374 145.273 149.945 1.00 48.96  ? 276 PHE A CB  1 
ATOM   382  C CG  . PHE A 1 276 ? 167.512 146.709 149.521 1.00 49.90  ? 276 PHE A CG  1 
ATOM   383  C CD1 . PHE A 1 276 ? 166.461 147.367 148.909 1.00 53.80  ? 276 PHE A CD1 1 
ATOM   384  C CD2 . PHE A 1 276 ? 168.692 147.398 149.728 1.00 50.34  ? 276 PHE A CD2 1 
ATOM   385  C CE1 . PHE A 1 276 ? 166.586 148.686 148.514 1.00 53.53  ? 276 PHE A CE1 1 
ATOM   386  C CE2 . PHE A 1 276 ? 168.820 148.717 149.335 1.00 49.94  ? 276 PHE A CE2 1 
ATOM   387  C CZ  . PHE A 1 276 ? 167.767 149.360 148.729 1.00 49.18  ? 276 PHE A CZ  1 
ATOM   388  N N   . LEU A 1 277 ? 169.362 144.199 147.742 1.00 49.86  ? 277 LEU A N   1 
ATOM   389  C CA  . LEU A 1 277 ? 170.325 144.464 146.682 1.00 50.61  ? 277 LEU A CA  1 
ATOM   390  C C   . LEU A 1 277 ? 169.938 143.755 145.392 1.00 52.44  ? 277 LEU A C   1 
ATOM   391  O O   . LEU A 1 277 ? 170.121 144.302 144.303 1.00 45.02  ? 277 LEU A O   1 
ATOM   392  C CB  . LEU A 1 277 ? 171.724 144.052 147.125 1.00 47.13  ? 277 LEU A CB  1 
ATOM   393  C CG  . LEU A 1 277 ? 172.323 144.875 148.260 1.00 46.64  ? 277 LEU A CG  1 
ATOM   394  C CD1 . LEU A 1 277 ? 173.748 144.450 148.500 1.00 48.88  ? 277 LEU A CD1 1 
ATOM   395  C CD2 . LEU A 1 277 ? 172.254 146.349 147.940 1.00 55.42  ? 277 LEU A CD2 1 
ATOM   396  N N   . LEU A 1 278 ? 169.396 142.538 145.492 1.00 55.41  ? 278 LEU A N   1 
ATOM   397  C CA  . LEU A 1 278 ? 168.961 141.829 144.293 1.00 47.96  ? 278 LEU A CA  1 
ATOM   398  C C   . LEU A 1 278 ? 167.816 142.556 143.596 1.00 45.57  ? 278 LEU A C   1 
ATOM   399  O O   . LEU A 1 278 ? 167.808 142.688 142.365 1.00 49.12  ? 278 LEU A O   1 
ATOM   400  C CB  . LEU A 1 278 ? 168.542 140.409 144.654 1.00 44.13  ? 278 LEU A CB  1 
ATOM   401  C CG  . LEU A 1 278 ? 168.053 139.565 143.483 1.00 45.69  ? 278 LEU A CG  1 
ATOM   402  C CD1 . LEU A 1 278 ? 169.217 139.200 142.584 1.00 52.06  ? 278 LEU A CD1 1 
ATOM   403  C CD2 . LEU A 1 278 ? 167.345 138.329 143.989 1.00 54.00  ? 278 LEU A CD2 1 
ATOM   404  N N   . ILE A 1 279 ? 166.834 143.027 144.366 1.00 45.10  ? 279 ILE A N   1 
ATOM   405  C CA  . ILE A 1 279 ? 165.702 143.736 143.772 1.00 38.67  ? 279 ILE A CA  1 
ATOM   406  C C   . ILE A 1 279 ? 166.157 145.052 143.160 1.00 39.60  ? 279 ILE A C   1 
ATOM   407  O O   . ILE A 1 279 ? 165.730 145.425 142.057 1.00 41.09  ? 279 ILE A O   1 
ATOM   408  C CB  . ILE A 1 279 ? 164.600 143.947 144.821 1.00 38.04  ? 279 ILE A CB  1 
ATOM   409  C CG1 . ILE A 1 279 ? 164.121 142.598 145.345 1.00 42.81  ? 279 ILE A CG1 1 
ATOM   410  C CG2 . ILE A 1 279 ? 163.446 144.712 144.222 1.00 35.68  ? 279 ILE A CG2 1 
ATOM   411  C CD1 . ILE A 1 279 ? 163.450 142.684 146.671 1.00 45.31  ? 279 ILE A CD1 1 
ATOM   412  N N   . GLU A 1 280 ? 167.026 145.780 143.865 1.00 40.99  ? 280 GLU A N   1 
ATOM   413  C CA  . GLU A 1 280 ? 167.593 146.999 143.304 1.00 40.44  ? 280 GLU A CA  1 
ATOM   414  C C   . GLU A 1 280 ? 168.344 146.705 142.015 1.00 45.53  ? 280 GLU A C   1 
ATOM   415  O O   . GLU A 1 280 ? 168.243 147.459 141.040 1.00 46.13  ? 280 GLU A O   1 
ATOM   416  C CB  . GLU A 1 280 ? 168.517 147.654 144.326 1.00 39.90  ? 280 GLU A CB  1 
ATOM   417  C CG  . GLU A 1 280 ? 169.409 148.727 143.749 1.00 45.36  ? 280 GLU A CG  1 
ATOM   418  C CD  . GLU A 1 280 ? 170.444 149.205 144.737 1.00 57.00  ? 280 GLU A CD  1 
ATOM   419  O OE1 . GLU A 1 280 ? 170.445 148.704 145.878 1.00 61.72  ? 280 GLU A OE1 1 
ATOM   420  O OE2 . GLU A 1 280 ? 171.257 150.080 144.379 1.00 58.72  ? 280 GLU A OE2 1 
ATOM   421  N N   . PHE A 1 281 ? 169.092 145.603 141.992 1.00 46.99  ? 281 PHE A N   1 
ATOM   422  C CA  . PHE A 1 281 ? 169.847 145.220 140.807 1.00 44.22  ? 281 PHE A CA  1 
ATOM   423  C C   . PHE A 1 281 ? 168.924 144.950 139.627 1.00 40.29  ? 281 PHE A C   1 
ATOM   424  O O   . PHE A 1 281 ? 169.199 145.387 138.507 1.00 38.98  ? 281 PHE A O   1 
ATOM   425  C CB  . PHE A 1 281 ? 170.699 143.995 141.136 1.00 42.70  ? 281 PHE A CB  1 
ATOM   426  C CG  . PHE A 1 281 ? 171.397 143.403 139.956 1.00 43.60  ? 281 PHE A CG  1 
ATOM   427  C CD1 . PHE A 1 281 ? 172.412 144.086 139.322 1.00 46.91  ? 281 PHE A CD1 1 
ATOM   428  C CD2 . PHE A 1 281 ? 171.056 142.148 139.497 1.00 45.67  ? 281 PHE A CD2 1 
ATOM   429  C CE1 . PHE A 1 281 ? 173.057 143.536 138.240 1.00 49.92  ? 281 PHE A CE1 1 
ATOM   430  C CE2 . PHE A 1 281 ? 171.704 141.596 138.419 1.00 48.15  ? 281 PHE A CE2 1 
ATOM   431  C CZ  . PHE A 1 281 ? 172.703 142.291 137.789 1.00 46.31  ? 281 PHE A CZ  1 
ATOM   432  N N   . LEU A 1 282 ? 167.817 144.243 139.860 1.00 41.03  ? 282 LEU A N   1 
ATOM   433  C CA  . LEU A 1 282 ? 166.888 143.956 138.769 1.00 37.21  ? 282 LEU A CA  1 
ATOM   434  C C   . LEU A 1 282 ? 166.211 145.224 138.258 1.00 37.21  ? 282 LEU A C   1 
ATOM   435  O O   . LEU A 1 282 ? 166.031 145.399 137.044 1.00 40.15  ? 282 LEU A O   1 
ATOM   436  C CB  . LEU A 1 282 ? 165.850 142.935 139.220 1.00 33.90  ? 282 LEU A CB  1 
ATOM   437  C CG  . LEU A 1 282 ? 166.422 141.553 139.525 1.00 31.69  ? 282 LEU A CG  1 
ATOM   438  C CD1 . LEU A 1 282 ? 165.340 140.630 140.034 1.00 35.76  ? 282 LEU A CD1 1 
ATOM   439  C CD2 . LEU A 1 282 ? 167.068 140.977 138.289 1.00 34.70  ? 282 LEU A CD2 1 
ATOM   440  N N   . PHE A 1 283 ? 165.829 146.124 139.163 1.00 36.49  ? 283 PHE A N   1 
ATOM   441  C CA  . PHE A 1 283 ? 165.229 147.380 138.721 1.00 35.97  ? 283 PHE A CA  1 
ATOM   442  C C   . PHE A 1 283 ? 166.212 148.201 137.892 1.00 38.83  ? 283 PHE A C   1 
ATOM   443  O O   . PHE A 1 283 ? 165.863 148.729 136.824 1.00 41.20  ? 283 PHE A O   1 
ATOM   444  C CB  . PHE A 1 283 ? 164.744 148.174 139.932 1.00 35.13  ? 283 PHE A CB  1 
ATOM   445  C CG  . PHE A 1 283 ? 164.249 149.542 139.595 1.00 38.53  ? 283 PHE A CG  1 
ATOM   446  C CD1 . PHE A 1 283 ? 163.044 149.715 138.943 1.00 39.00  ? 283 PHE A CD1 1 
ATOM   447  C CD2 . PHE A 1 283 ? 164.986 150.661 139.935 1.00 39.20  ? 283 PHE A CD2 1 
ATOM   448  C CE1 . PHE A 1 283 ? 162.588 150.981 138.633 1.00 41.71  ? 283 PHE A CE1 1 
ATOM   449  C CE2 . PHE A 1 283 ? 164.533 151.928 139.629 1.00 35.78  ? 283 PHE A CE2 1 
ATOM   450  C CZ  . PHE A 1 283 ? 163.334 152.087 138.978 1.00 39.52  ? 283 PHE A CZ  1 
ATOM   451  N N   . LEU A 1 284 ? 167.458 148.300 138.352 1.00 38.39  ? 284 LEU A N   1 
ATOM   452  C CA  . LEU A 1 284 ? 168.457 149.039 137.597 1.00 35.28  ? 284 LEU A CA  1 
ATOM   453  C C   . LEU A 1 284 ? 168.790 148.346 136.282 1.00 37.52  ? 284 LEU A C   1 
ATOM   454  O O   . LEU A 1 284 ? 169.156 149.013 135.315 1.00 37.87  ? 284 LEU A O   1 
ATOM   455  C CB  . LEU A 1 284 ? 169.708 149.237 138.448 1.00 37.21  ? 284 LEU A CB  1 
ATOM   456  C CG  . LEU A 1 284 ? 169.466 150.042 139.728 1.00 33.52  ? 284 LEU A CG  1 
ATOM   457  C CD1 . LEU A 1 284 ? 170.709 150.110 140.587 1.00 34.83  ? 284 LEU A CD1 1 
ATOM   458  C CD2 . LEU A 1 284 ? 168.978 151.432 139.392 1.00 37.62  ? 284 LEU A CD2 1 
ATOM   459  N N   . LEU A 1 285 ? 168.662 147.020 136.216 1.00 40.02  ? 285 LEU A N   1 
ATOM   460  C CA  . LEU A 1 285 ? 168.816 146.325 134.941 1.00 36.10  ? 285 LEU A CA  1 
ATOM   461  C C   . LEU A 1 285 ? 167.710 146.706 133.970 1.00 35.08  ? 285 LEU A C   1 
ATOM   462  O O   . LEU A 1 285 ? 167.952 146.846 132.767 1.00 38.09  ? 285 LEU A O   1 
ATOM   463  C CB  . LEU A 1 285 ? 168.822 144.816 135.151 1.00 33.65  ? 285 LEU A CB  1 
ATOM   464  C CG  . LEU A 1 285 ? 170.128 144.202 135.618 1.00 35.56  ? 285 LEU A CG  1 
ATOM   465  C CD1 . LEU A 1 285 ? 169.979 142.707 135.625 1.00 39.84  ? 285 LEU A CD1 1 
ATOM   466  C CD2 . LEU A 1 285 ? 171.238 144.627 134.694 1.00 40.75  ? 285 LEU A CD2 1 
ATOM   467  N N   . GLY A 1 286 ? 166.482 146.835 134.467 1.00 34.88  ? 286 GLY A N   1 
ATOM   468  C CA  . GLY A 1 286 ? 165.415 147.331 133.612 1.00 40.36  ? 286 GLY A CA  1 
ATOM   469  C C   . GLY A 1 286 ? 165.714 148.719 133.082 1.00 44.38  ? 286 GLY A C   1 
ATOM   470  O O   . GLY A 1 286 ? 165.503 149.007 131.898 1.00 47.61  ? 286 GLY A O   1 
ATOM   471  N N   . ILE A 1 287 ? 166.231 149.592 133.948 1.00 44.12  ? 287 ILE A N   1 
ATOM   472  C CA  . ILE A 1 287 ? 166.612 150.931 133.501 1.00 35.37  ? 287 ILE A CA  1 
ATOM   473  C C   . ILE A 1 287 ? 167.724 150.852 132.461 1.00 41.96  ? 287 ILE A C   1 
ATOM   474  O O   . ILE A 1 287 ? 167.718 151.592 131.471 1.00 46.02  ? 287 ILE A O   1 
ATOM   475  C CB  . ILE A 1 287 ? 167.016 151.811 134.696 1.00 30.34  ? 287 ILE A CB  1 
ATOM   476  C CG1 . ILE A 1 287 ? 165.813 152.071 135.588 1.00 34.38  ? 287 ILE A CG1 1 
ATOM   477  C CG2 . ILE A 1 287 ? 167.570 153.127 134.217 1.00 32.29  ? 287 ILE A CG2 1 
ATOM   478  C CD1 . ILE A 1 287 ? 166.107 153.003 136.726 1.00 33.79  ? 287 ILE A CD1 1 
ATOM   479  N N   . ASN A 1 288 ? 168.695 149.958 132.666 1.00 42.81  ? 288 ASN A N   1 
ATOM   480  C CA  . ASN A 1 288 ? 169.776 149.802 131.698 1.00 43.35  ? 288 ASN A CA  1 
ATOM   481  C C   . ASN A 1 288 ? 169.245 149.345 130.347 1.00 49.48  ? 288 ASN A C   1 
ATOM   482  O O   . ASN A 1 288 ? 169.699 149.820 129.302 1.00 48.87  ? 288 ASN A O   1 
ATOM   483  C CB  . ASN A 1 288 ? 170.816 148.806 132.209 1.00 38.42  ? 288 ASN A CB  1 
ATOM   484  C CG  . ASN A 1 288 ? 171.587 149.321 133.396 1.00 40.82  ? 288 ASN A CG  1 
ATOM   485  O OD1 . ASN A 1 288 ? 172.427 150.203 133.267 1.00 46.23  ? 288 ASN A OD1 1 
ATOM   486  N ND2 . ASN A 1 288 ? 171.323 148.753 134.561 1.00 41.58  ? 288 ASN A ND2 1 
ATOM   487  N N   . THR A 1 289 ? 168.303 148.403 130.351 1.00 52.48  ? 289 THR A N   1 
ATOM   488  C CA  . THR A 1 289 ? 167.727 147.930 129.097 1.00 47.80  ? 289 THR A CA  1 
ATOM   489  C C   . THR A 1 289 ? 166.992 149.050 128.380 1.00 51.03  ? 289 THR A C   1 
ATOM   490  O O   . THR A 1 289 ? 167.108 149.199 127.156 1.00 58.71  ? 289 THR A O   1 
ATOM   491  C CB  . THR A 1 289 ? 166.782 146.762 129.356 1.00 45.42  ? 289 THR A CB  1 
ATOM   492  O OG1 . THR A 1 289 ? 167.445 145.774 130.154 1.00 46.94  ? 289 THR A OG1 1 
ATOM   493  C CG2 . THR A 1 289 ? 166.348 146.145 128.043 1.00 54.51  ? 289 THR A CG2 1 
ATOM   494  N N   . TYR A 1 290 ? 166.231 149.855 129.127 1.00 48.34  ? 290 TYR A N   1 
ATOM   495  C CA  . TYR A 1 290 ? 165.574 151.005 128.515 1.00 48.89  ? 290 TYR A CA  1 
ATOM   496  C C   . TYR A 1 290 ? 166.593 151.964 127.917 1.00 49.33  ? 290 TYR A C   1 
ATOM   497  O O   . TYR A 1 290 ? 166.412 152.459 126.798 1.00 55.87  ? 290 TYR A O   1 
ATOM   498  C CB  . TYR A 1 290 ? 164.708 151.733 129.539 1.00 54.64  ? 290 TYR A CB  1 
ATOM   499  C CG  . TYR A 1 290 ? 164.098 153.011 129.013 1.00 54.51  ? 290 TYR A CG  1 
ATOM   500  C CD1 . TYR A 1 290 ? 162.926 152.987 128.275 1.00 57.39  ? 290 TYR A CD1 1 
ATOM   501  C CD2 . TYR A 1 290 ? 164.693 154.241 129.254 1.00 56.11  ? 290 TYR A CD2 1 
ATOM   502  C CE1 . TYR A 1 290 ? 162.367 154.147 127.788 1.00 60.07  ? 290 TYR A CE1 1 
ATOM   503  C CE2 . TYR A 1 290 ? 164.141 155.407 128.770 1.00 57.86  ? 290 TYR A CE2 1 
ATOM   504  C CZ  . TYR A 1 290 ? 162.976 155.354 128.041 1.00 61.32  ? 290 TYR A CZ  1 
ATOM   505  O OH  . TYR A 1 290 ? 162.416 156.512 127.556 1.00 69.32  ? 290 TYR A OH  1 
ATOM   506  N N   . GLY A 1 291 ? 167.670 152.240 128.654 1.00 44.95  ? 291 GLY A N   1 
ATOM   507  C CA  . GLY A 1 291 ? 168.682 153.152 128.153 1.00 48.71  ? 291 GLY A CA  1 
ATOM   508  C C   . GLY A 1 291 ? 169.352 152.644 126.893 1.00 55.75  ? 291 GLY A C   1 
ATOM   509  O O   . GLY A 1 291 ? 169.585 153.405 125.953 1.00 60.54  ? 291 GLY A O   1 
ATOM   510  N N   . TRP A 1 292 ? 169.671 151.349 126.857 1.00 55.78  ? 292 TRP A N   1 
ATOM   511  C CA  . TRP A 1 292 ? 170.288 150.775 125.666 1.00 59.89  ? 292 TRP A CA  1 
ATOM   512  C C   . TRP A 1 292 ? 169.344 150.835 124.474 1.00 61.77  ? 292 TRP A C   1 
ATOM   513  O O   . TRP A 1 292 ? 169.764 151.163 123.358 1.00 62.92  ? 292 TRP A O   1 
ATOM   514  C CB  . TRP A 1 292 ? 170.713 149.331 125.926 1.00 60.15  ? 292 TRP A CB  1 
ATOM   515  C CG  . TRP A 1 292 ? 171.608 149.154 127.100 1.00 58.44  ? 292 TRP A CG  1 
ATOM   516  C CD1 . TRP A 1 292 ? 172.457 150.075 127.627 1.00 56.87  ? 292 TRP A CD1 1 
ATOM   517  C CD2 . TRP A 1 292 ? 171.729 147.983 127.912 1.00 58.64  ? 292 TRP A CD2 1 
ATOM   518  N NE1 . TRP A 1 292 ? 173.106 149.550 128.716 1.00 56.05  ? 292 TRP A NE1 1 
ATOM   519  C CE2 . TRP A 1 292 ? 172.673 148.266 128.913 1.00 58.20  ? 292 TRP A CE2 1 
ATOM   520  C CE3 . TRP A 1 292 ? 171.130 146.721 127.889 1.00 56.79  ? 292 TRP A CE3 1 
ATOM   521  C CZ2 . TRP A 1 292 ? 173.034 147.336 129.878 1.00 60.08  ? 292 TRP A CZ2 1 
ATOM   522  C CZ3 . TRP A 1 292 ? 171.489 145.799 128.850 1.00 55.77  ? 292 TRP A CZ3 1 
ATOM   523  C CH2 . TRP A 1 292 ? 172.430 146.111 129.831 1.00 55.51  ? 292 TRP A CH2 1 
ATOM   524  N N   . ARG A 1 293 ? 168.066 150.508 124.683 1.00 59.63  ? 293 ARG A N   1 
ATOM   525  C CA  . ARG A 1 293 ? 167.124 150.534 123.570 1.00 57.41  ? 293 ARG A CA  1 
ATOM   526  C C   . ARG A 1 293 ? 166.925 151.949 123.045 1.00 59.58  ? 293 ARG A C   1 
ATOM   527  O O   . ARG A 1 293 ? 166.847 152.160 121.830 1.00 66.00  ? 293 ARG A O   1 
ATOM   528  C CB  . ARG A 1 293 ? 165.785 149.931 123.988 1.00 59.73  ? 293 ARG A CB  1 
ATOM   529  C CG  . ARG A 1 293 ? 164.874 149.619 122.814 1.00 71.42  ? 293 ARG A CG  1 
ATOM   530  C CD  . ARG A 1 293 ? 163.460 149.296 123.265 1.00 72.99  ? 293 ARG A CD  1 
ATOM   531  N NE  . ARG A 1 293 ? 162.696 150.497 123.578 1.00 79.66  ? 293 ARG A NE  1 
ATOM   532  C CZ  . ARG A 1 293 ? 161.395 150.511 123.831 1.00 87.34  ? 293 ARG A CZ  1 
ATOM   533  N NH1 . ARG A 1 293 ? 160.677 149.400 123.824 1.00 89.95  ? 293 ARG A NH1 1 
ATOM   534  N NH2 . ARG A 1 293 ? 160.797 151.669 124.095 1.00 93.12  ? 293 ARG A NH2 1 
ATOM   535  N N   . GLN A 1 294 ? 166.837 152.932 123.943 1.00 58.51  ? 294 GLN A N   1 
ATOM   536  C CA  . GLN A 1 294 ? 166.612 154.306 123.505 1.00 60.96  ? 294 GLN A CA  1 
ATOM   537  C C   . GLN A 1 294 ? 167.856 154.898 122.857 1.00 66.25  ? 294 GLN A C   1 
ATOM   538  O O   . GLN A 1 294 ? 167.753 155.692 121.915 1.00 67.89  ? 294 GLN A O   1 
ATOM   539  C CB  . GLN A 1 294 ? 166.164 155.167 124.685 1.00 57.98  ? 294 GLN A CB  1 
ATOM   540  C CG  . GLN A 1 294 ? 164.771 154.854 125.177 1.00 60.11  ? 294 GLN A CG  1 
ATOM   541  C CD  . GLN A 1 294 ? 163.725 155.050 124.103 1.00 70.54  ? 294 GLN A CD  1 
ATOM   542  O OE1 . GLN A 1 294 ? 163.081 154.097 123.667 1.00 71.68  ? 294 GLN A OE1 1 
ATOM   543  N NE2 . GLN A 1 294 ? 163.549 156.292 123.668 1.00 72.47  ? 294 GLN A NE2 1 
ATOM   544  N N   . ALA A 1 295 ? 169.036 154.528 123.343 1.00 62.63  ? 295 ALA A N   1 
ATOM   545  C CA  . ALA A 1 295 ? 170.289 155.085 122.857 1.00 60.74  ? 295 ALA A CA  1 
ATOM   546  C C   . ALA A 1 295 ? 170.860 154.320 121.673 1.00 65.22  ? 295 ALA A C   1 
ATOM   547  O O   . ALA A 1 295 ? 171.958 154.647 121.214 1.00 69.76  ? 295 ALA A O   1 
ATOM   548  C CB  . ALA A 1 295 ? 171.320 155.126 123.987 1.00 62.29  ? 295 ALA A CB  1 
ATOM   549  N N   . GLY A 1 296 ? 170.153 153.313 121.173 1.00 68.09  ? 296 GLY A N   1 
ATOM   550  C CA  . GLY A 1 296 ? 170.613 152.560 120.030 1.00 69.82  ? 296 GLY A CA  1 
ATOM   551  C C   . GLY A 1 296 ? 171.633 151.489 120.331 1.00 73.45  ? 296 GLY A C   1 
ATOM   552  O O   . GLY A 1 296 ? 172.184 150.905 119.390 1.00 78.99  ? 296 GLY A O   1 
ATOM   553  N N   . VAL A 1 297 ? 171.905 151.204 121.603 1.00 71.28  ? 297 VAL A N   1 
ATOM   554  C CA  . VAL A 1 297 ? 172.866 150.165 121.953 1.00 69.78  ? 297 VAL A CA  1 
ATOM   555  C C   . VAL A 1 297 ? 172.255 148.815 121.616 1.00 73.75  ? 297 VAL A C   1 
ATOM   556  O O   . VAL A 1 297 ? 171.397 148.309 122.346 1.00 73.64  ? 297 VAL A O   1 
ATOM   557  C CB  . VAL A 1 297 ? 173.264 150.232 123.438 1.00 61.65  ? 297 VAL A CB  1 
ATOM   558  C CG1 . VAL A 1 297 ? 174.263 149.141 123.762 1.00 61.01  ? 297 VAL A CG1 1 
ATOM   559  C CG2 . VAL A 1 297 ? 173.836 151.592 123.773 1.00 70.77  ? 297 VAL A CG2 1 
ATOM   560  N N   . ASN A 1 298 ? 172.698 148.218 120.511 1.00 75.80  ? 298 ASN A N   1 
ATOM   561  C CA  . ASN A 1 298 ? 172.141 146.953 120.040 1.00 71.67  ? 298 ASN A CA  1 
ATOM   562  C C   . ASN A 1 298 ? 172.677 145.836 120.928 1.00 68.93  ? 298 ASN A C   1 
ATOM   563  O O   . ASN A 1 298 ? 173.543 145.046 120.546 1.00 74.93  ? 298 ASN A O   1 
ATOM   564  C CB  . ASN A 1 298 ? 172.487 146.730 118.575 1.00 70.62  ? 298 ASN A CB  1 
ATOM   565  C CG  . ASN A 1 298 ? 171.811 145.507 117.999 1.00 69.95  ? 298 ASN A CG  1 
ATOM   566  O OD1 . ASN A 1 298 ? 172.303 144.390 118.139 1.00 71.65  ? 298 ASN A OD1 1 
ATOM   567  N ND2 . ASN A 1 298 ? 170.679 145.713 117.337 1.00 66.96  ? 298 ASN A ND2 1 
ATOM   568  N N   . HIS A 1 299 ? 172.143 145.773 122.144 1.00 65.75  ? 299 HIS A N   1 
ATOM   569  C CA  . HIS A 1 299 ? 172.570 144.764 123.100 1.00 68.91  ? 299 HIS A CA  1 
ATOM   570  C C   . HIS A 1 299 ? 172.045 143.377 122.765 1.00 72.83  ? 299 HIS A C   1 
ATOM   571  O O   . HIS A 1 299 ? 172.521 142.396 123.346 1.00 73.13  ? 299 HIS A O   1 
ATOM   572  C CB  . HIS A 1 299 ? 172.123 145.156 124.509 1.00 64.02  ? 299 HIS A CB  1 
ATOM   573  C CG  . HIS A 1 299 ? 170.647 145.048 124.724 1.00 67.98  ? 299 HIS A CG  1 
ATOM   574  N ND1 . HIS A 1 299 ? 169.742 145.893 124.119 1.00 72.57  ? 299 HIS A ND1 1 
ATOM   575  C CD2 . HIS A 1 299 ? 169.918 144.196 125.481 1.00 66.93  ? 299 HIS A CD2 1 
ATOM   576  C CE1 . HIS A 1 299 ? 168.518 145.564 124.492 1.00 68.76  ? 299 HIS A CE1 1 
ATOM   577  N NE2 . HIS A 1 299 ? 168.597 144.538 125.320 1.00 68.62  ? 299 HIS A NE2 1 
ATOM   578  N N   . VAL A 1 300 ? 171.083 143.272 121.847 1.00 70.82  ? 300 VAL A N   1 
ATOM   579  C CA  . VAL A 1 300 ? 170.522 141.970 121.503 1.00 73.16  ? 300 VAL A CA  1 
ATOM   580  C C   . VAL A 1 300 ? 171.581 141.086 120.856 1.00 75.56  ? 300 VAL A C   1 
ATOM   581  O O   . VAL A 1 300 ? 171.699 139.898 121.173 1.00 78.11  ? 300 VAL A O   1 
ATOM   582  C CB  . VAL A 1 300 ? 169.285 142.141 120.603 1.00 76.42  ? 300 VAL A CB  1 
ATOM   583  C CG1 . VAL A 1 300 ? 168.126 142.691 121.410 1.00 78.38  ? 300 VAL A CG1 1 
ATOM   584  C CG2 . VAL A 1 300 ? 169.588 143.070 119.440 1.00 76.52  ? 300 VAL A CG2 1 
ATOM   585  N N   . LEU A 1 301 ? 172.369 141.651 119.940 1.00 73.51  ? 301 LEU A N   1 
ATOM   586  C CA  . LEU A 1 301 ? 173.474 140.903 119.355 1.00 75.14  ? 301 LEU A CA  1 
ATOM   587  C C   . LEU A 1 301 ? 174.652 140.792 120.309 1.00 76.14  ? 301 LEU A C   1 
ATOM   588  O O   . LEU A 1 301 ? 175.396 139.808 120.256 1.00 80.93  ? 301 LEU A O   1 
ATOM   589  C CB  . LEU A 1 301 ? 173.927 141.556 118.050 1.00 74.04  ? 301 LEU A CB  1 
ATOM   590  C CG  . LEU A 1 301 ? 172.927 141.539 116.896 1.00 78.10  ? 301 LEU A CG  1 
ATOM   591  C CD1 . LEU A 1 301 ? 173.469 142.329 115.716 1.00 76.20  ? 301 LEU A CD1 1 
ATOM   592  C CD2 . LEU A 1 301 ? 172.604 140.113 116.489 1.00 76.01  ? 301 LEU A CD2 1 
ATOM   593  N N   . ILE A 1 302 ? 174.843 141.788 121.175 1.00 73.33  ? 302 ILE A N   1 
ATOM   594  C CA  . ILE A 1 302 ? 175.985 141.772 122.083 1.00 72.49  ? 302 ILE A CA  1 
ATOM   595  C C   . ILE A 1 302 ? 175.856 140.628 123.076 1.00 71.95  ? 302 ILE A C   1 
ATOM   596  O O   . ILE A 1 302 ? 176.794 139.849 123.279 1.00 76.54  ? 302 ILE A O   1 
ATOM   597  C CB  . ILE A 1 302 ? 176.119 143.126 122.798 1.00 66.06  ? 302 ILE A CB  1 
ATOM   598  C CG1 . ILE A 1 302 ? 176.427 144.229 121.785 1.00 68.77  ? 302 ILE A CG1 1 
ATOM   599  C CG2 . ILE A 1 302 ? 177.169 143.041 123.886 1.00 65.86  ? 302 ILE A CG2 1 
ATOM   600  C CD1 . ILE A 1 302 ? 177.471 143.849 120.765 1.00 73.68  ? 302 ILE A CD1 1 
ATOM   601  N N   . PHE A 1 303 ? 174.690 140.497 123.697 1.00 65.81  ? 303 PHE A N   1 
ATOM   602  C CA  . PHE A 1 303 ? 174.453 139.404 124.629 1.00 67.58  ? 303 PHE A CA  1 
ATOM   603  C C   . PHE A 1 303 ? 174.210 138.075 123.929 1.00 76.14  ? 303 PHE A C   1 
ATOM   604  O O   . PHE A 1 303 ? 174.039 137.061 124.614 1.00 79.39  ? 303 PHE A O   1 
ATOM   605  C CB  . PHE A 1 303 ? 173.264 139.728 125.534 1.00 64.66  ? 303 PHE A CB  1 
ATOM   606  C CG  . PHE A 1 303 ? 173.630 140.488 126.773 1.00 57.94  ? 303 PHE A CG  1 
ATOM   607  C CD1 . PHE A 1 303 ? 174.010 139.821 127.921 1.00 50.77  ? 303 PHE A CD1 1 
ATOM   608  C CD2 . PHE A 1 303 ? 173.577 141.867 126.797 1.00 55.09  ? 303 PHE A CD2 1 
ATOM   609  C CE1 . PHE A 1 303 ? 174.338 140.515 129.063 1.00 44.06  ? 303 PHE A CE1 1 
ATOM   610  C CE2 . PHE A 1 303 ? 173.905 142.563 127.938 1.00 47.07  ? 303 PHE A CE2 1 
ATOM   611  C CZ  . PHE A 1 303 ? 174.286 141.885 129.071 1.00 43.15  ? 303 PHE A CZ  1 
ATOM   612  N N   . GLU A 1 304 ? 174.182 138.062 122.594 1.00 74.74  ? 304 GLU A N   1 
ATOM   613  C CA  . GLU A 1 304 ? 173.883 136.862 121.809 1.00 76.43  ? 304 GLU A CA  1 
ATOM   614  C C   . GLU A 1 304 ? 172.496 136.317 122.142 1.00 81.13  ? 304 GLU A C   1 
ATOM   615  O O   . GLU A 1 304 ? 172.267 135.106 122.142 1.00 79.32  ? 304 GLU A O   1 
ATOM   616  C CB  . GLU A 1 304 ? 174.953 135.785 122.003 1.00 79.59  ? 304 GLU A CB  1 
ATOM   617  C CG  . GLU A 1 304 ? 176.374 136.275 121.803 1.00 80.12  ? 304 GLU A CG  1 
ATOM   618  C CD  . GLU A 1 304 ? 176.644 136.742 120.388 1.00 86.23  ? 304 GLU A CD  1 
ATOM   619  O OE1 . GLU A 1 304 ? 176.004 136.220 119.451 1.00 92.38  ? 304 GLU A OE1 1 
ATOM   620  O OE2 . GLU A 1 304 ? 177.499 137.633 120.212 1.00 81.97  ? 304 GLU A OE2 1 
ATOM   621  N N   . LEU A 1 305 ? 171.565 137.219 122.434 1.00 82.94  ? 305 LEU A N   1 
ATOM   622  C CA  . LEU A 1 305 ? 170.192 136.826 122.693 1.00 80.84  ? 305 LEU A CA  1 
ATOM   623  C C   . LEU A 1 305 ? 169.441 136.634 121.381 1.00 84.98  ? 305 LEU A C   1 
ATOM   624  O O   . LEU A 1 305 ? 169.816 137.168 120.335 1.00 84.29  ? 305 LEU A O   1 
ATOM   625  C CB  . LEU A 1 305 ? 169.482 137.871 123.552 1.00 76.55  ? 305 LEU A CB  1 
ATOM   626  C CG  . LEU A 1 305 ? 170.015 138.082 124.968 1.00 72.89  ? 305 LEU A CG  1 
ATOM   627  C CD1 . LEU A 1 305 ? 169.145 139.069 125.724 1.00 71.54  ? 305 LEU A CD1 1 
ATOM   628  C CD2 . LEU A 1 305 ? 170.099 136.765 125.710 1.00 69.37  ? 305 LEU A CD2 1 
ATOM   629  N N   . ASN A 1 306 ? 168.369 135.858 121.449 1.00 90.96  ? 306 ASN A N   1 
ATOM   630  C CA  . ASN A 1 306 ? 167.543 135.629 120.273 1.00 94.48  ? 306 ASN A CA  1 
ATOM   631  C C   . ASN A 1 306 ? 166.865 136.931 119.863 1.00 95.42  ? 306 ASN A C   1 
ATOM   632  O O   . ASN A 1 306 ? 166.252 137.595 120.704 1.00 94.19  ? 306 ASN A O   1 
ATOM   633  C CB  . ASN A 1 306 ? 166.498 134.552 120.554 1.00 92.86  ? 306 ASN A CB  1 
ATOM   634  C CG  . ASN A 1 306 ? 167.120 133.224 120.945 1.00 89.89  ? 306 ASN A CG  1 
ATOM   635  O OD1 . ASN A 1 306 ? 168.252 133.173 121.426 1.00 93.50  ? 306 ASN A OD1 1 
ATOM   636  N ND2 . ASN A 1 306 ? 166.381 132.141 120.737 1.00 85.10  ? 306 ASN A ND2 1 
ATOM   637  N N   . PRO A 1 307 ? 166.958 137.332 118.594 1.00 98.12  ? 307 PRO A N   1 
ATOM   638  C CA  . PRO A 1 307 ? 166.343 138.605 118.186 1.00 103.78 ? 307 PRO A CA  1 
ATOM   639  C C   . PRO A 1 307 ? 164.841 138.647 118.391 1.00 105.07 ? 307 PRO A C   1 
ATOM   640  O O   . PRO A 1 307 ? 164.292 139.721 118.664 1.00 104.00 ? 307 PRO A O   1 
ATOM   641  C CB  . PRO A 1 307 ? 166.716 138.709 116.700 1.00 103.80 ? 307 PRO A CB  1 
ATOM   642  C CG  . PRO A 1 307 ? 166.943 137.297 116.269 1.00 99.50  ? 307 PRO A CG  1 
ATOM   643  C CD  . PRO A 1 307 ? 167.547 136.607 117.456 1.00 95.20  ? 307 PRO A CD  1 
ATOM   644  N N   . ARG A 1 308 ? 164.158 137.512 118.268 1.00 104.79 ? 308 ARG A N   1 
ATOM   645  C CA  . ARG A 1 308 ? 162.714 137.446 118.442 1.00 105.58 ? 308 ARG A CA  1 
ATOM   646  C C   . ARG A 1 308 ? 162.302 137.090 119.863 1.00 102.66 ? 308 ARG A C   1 
ATOM   647  O O   . ARG A 1 308 ? 161.102 136.988 120.136 1.00 101.81 ? 308 ARG A O   1 
ATOM   648  C CB  . ARG A 1 308 ? 162.114 136.433 117.464 1.00 111.48 ? 308 ARG A CB  1 
ATOM   649  C CG  . ARG A 1 308 ? 162.411 136.732 116.005 1.00 116.74 ? 308 ARG A CG  1 
ATOM   650  C CD  . ARG A 1 308 ? 161.883 135.633 115.099 1.00 126.24 ? 308 ARG A CD  1 
ATOM   651  N NE  . ARG A 1 308 ? 162.124 135.926 113.691 1.00 134.77 ? 308 ARG A NE  1 
ATOM   652  C CZ  . ARG A 1 308 ? 163.207 135.557 113.022 1.00 138.25 ? 308 ARG A CZ  1 
ATOM   653  N NH1 . ARG A 1 308 ? 164.179 134.873 113.603 1.00 136.51 ? 308 ARG A NH1 1 
ATOM   654  N NH2 . ARG A 1 308 ? 163.319 135.882 111.737 1.00 141.88 ? 308 ARG A NH2 1 
ATOM   655  N N   . SER A 1 309 ? 163.257 136.899 120.771 1.00 100.18 ? 309 SER A N   1 
ATOM   656  C CA  . SER A 1 309 ? 162.959 136.556 122.162 1.00 98.00  ? 309 SER A CA  1 
ATOM   657  C C   . SER A 1 309 ? 163.852 137.408 123.057 1.00 93.89  ? 309 SER A C   1 
ATOM   658  O O   . SER A 1 309 ? 165.051 137.143 123.179 1.00 88.54  ? 309 SER A O   1 
ATOM   659  C CB  . SER A 1 309 ? 163.170 135.070 122.423 1.00 95.20  ? 309 SER A CB  1 
ATOM   660  O OG  . SER A 1 309 ? 162.907 134.754 123.778 1.00 93.12  ? 309 SER A OG  1 
ATOM   661  N N   . ASN A 1 310 ? 163.265 138.427 123.683 1.00 93.93  ? 310 ASN A N   1 
ATOM   662  C CA  . ASN A 1 310 ? 163.987 139.321 124.574 1.00 88.13  ? 310 ASN A CA  1 
ATOM   663  C C   . ASN A 1 310 ? 163.122 139.656 125.778 1.00 84.66  ? 310 ASN A C   1 
ATOM   664  O O   . ASN A 1 310 ? 161.893 139.573 125.721 1.00 87.95  ? 310 ASN A O   1 
ATOM   665  C CB  . ASN A 1 310 ? 164.394 140.611 123.863 1.00 85.92  ? 310 ASN A CB  1 
ATOM   666  C CG  . ASN A 1 310 ? 165.122 140.350 122.569 1.00 92.47  ? 310 ASN A CG  1 
ATOM   667  O OD1 . ASN A 1 310 ? 164.510 140.274 121.505 1.00 96.46  ? 310 ASN A OD1 1 
ATOM   668  N ND2 . ASN A 1 310 ? 166.435 140.198 122.652 1.00 92.80  ? 310 ASN A ND2 1 
ATOM   669  N N   . LEU A 1 311 ? 163.776 140.036 126.869 1.00 77.41  ? 311 LEU A N   1 
ATOM   670  C CA  . LEU A 1 311 ? 163.091 140.478 128.080 1.00 67.61  ? 311 LEU A CA  1 
ATOM   671  C C   . LEU A 1 311 ? 163.149 141.999 128.109 1.00 72.51  ? 311 LEU A C   1 
ATOM   672  O O   . LEU A 1 311 ? 164.147 142.583 128.537 1.00 71.24  ? 311 LEU A O   1 
ATOM   673  C CB  . LEU A 1 311 ? 163.731 139.877 129.325 1.00 60.92  ? 311 LEU A CB  1 
ATOM   674  C CG  . LEU A 1 311 ? 162.808 139.832 130.538 1.00 61.89  ? 311 LEU A CG  1 
ATOM   675  C CD1 . LEU A 1 311 ? 161.702 138.832 130.280 1.00 69.69  ? 311 LEU A CD1 1 
ATOM   676  C CD2 . LEU A 1 311 ? 163.566 139.484 131.799 1.00 59.46  ? 311 LEU A CD2 1 
ATOM   677  N N   . SER A 1 312 ? 162.075 142.642 127.658 1.00 71.49  ? 312 SER A N   1 
ATOM   678  C CA  . SER A 1 312 ? 162.055 144.092 127.596 1.00 63.91  ? 312 SER A CA  1 
ATOM   679  C C   . SER A 1 312 ? 162.103 144.683 129.003 1.00 58.35  ? 312 SER A C   1 
ATOM   680  O O   . SER A 1 312 ? 161.902 143.994 130.006 1.00 56.98  ? 312 SER A O   1 
ATOM   681  C CB  . SER A 1 312 ? 160.818 144.581 126.846 1.00 63.33  ? 312 SER A CB  1 
ATOM   682  O OG  . SER A 1 312 ? 159.631 144.135 127.475 1.00 64.03  ? 312 SER A OG  1 
ATOM   683  N N   . HIS A 1 313 ? 162.380 145.987 129.066 1.00 55.75  ? 313 HIS A N   1 
ATOM   684  C CA  . HIS A 1 313 ? 162.586 146.640 130.354 1.00 56.80  ? 313 HIS A CA  1 
ATOM   685  C C   . HIS A 1 313 ? 161.351 146.559 131.239 1.00 52.54  ? 313 HIS A C   1 
ATOM   686  O O   . HIS A 1 313 ? 161.474 146.502 132.469 1.00 48.65  ? 313 HIS A O   1 
ATOM   687  C CB  . HIS A 1 313 ? 162.992 148.097 130.142 1.00 55.29  ? 313 HIS A CB  1 
ATOM   688  C CG  . HIS A 1 313 ? 162.064 148.862 129.254 1.00 53.03  ? 313 HIS A CG  1 
ATOM   689  N ND1 . HIS A 1 313 ? 162.081 148.744 127.882 1.00 54.11  ? 313 HIS A ND1 1 
ATOM   690  C CD2 . HIS A 1 313 ? 161.100 149.767 129.542 1.00 52.98  ? 313 HIS A CD2 1 
ATOM   691  C CE1 . HIS A 1 313 ? 161.162 149.538 127.363 1.00 62.30  ? 313 HIS A CE1 1 
ATOM   692  N NE2 . HIS A 1 313 ? 160.552 150.169 128.349 1.00 62.80  ? 313 HIS A NE2 1 
ATOM   693  N N   . GLN A 1 314 ? 160.160 146.545 130.641 1.00 51.73  ? 314 GLN A N   1 
ATOM   694  C CA  . GLN A 1 314 ? 158.943 146.462 131.439 1.00 51.50  ? 314 GLN A CA  1 
ATOM   695  C C   . GLN A 1 314 ? 158.865 145.140 132.187 1.00 52.77  ? 314 GLN A C   1 
ATOM   696  O O   . GLN A 1 314 ? 158.385 145.095 133.325 1.00 56.67  ? 314 GLN A O   1 
ATOM   697  C CB  . GLN A 1 314 ? 157.717 146.663 130.553 1.00 47.89  ? 314 GLN A CB  1 
ATOM   698  C CG  . GLN A 1 314 ? 157.658 148.040 129.929 1.00 57.39  ? 314 GLN A CG  1 
ATOM   699  C CD  . GLN A 1 314 ? 156.255 148.450 129.548 1.00 62.57  ? 314 GLN A CD  1 
ATOM   700  O OE1 . GLN A 1 314 ? 155.285 147.787 129.909 1.00 67.21  ? 314 GLN A OE1 1 
ATOM   701  N NE2 . GLN A 1 314 ? 156.139 149.549 128.816 1.00 65.02  ? 314 GLN A NE2 1 
ATOM   702  N N   . HIS A 1 315 ? 159.337 144.054 131.574 1.00 50.66  ? 315 HIS A N   1 
ATOM   703  C CA  . HIS A 1 315 ? 159.354 142.772 132.269 1.00 51.61  ? 315 HIS A CA  1 
ATOM   704  C C   . HIS A 1 315 ? 160.279 142.808 133.479 1.00 50.92  ? 315 HIS A C   1 
ATOM   705  O O   . HIS A 1 315 ? 159.942 142.278 134.543 1.00 50.23  ? 315 HIS A O   1 
ATOM   706  C CB  . HIS A 1 315 ? 159.767 141.665 131.311 1.00 52.05  ? 315 HIS A CB  1 
ATOM   707  C CG  . HIS A 1 315 ? 158.760 141.389 130.244 1.00 55.66  ? 315 HIS A CG  1 
ATOM   708  N ND1 . HIS A 1 315 ? 157.498 140.914 130.520 1.00 59.05  ? 315 HIS A ND1 1 
ATOM   709  C CD2 . HIS A 1 315 ? 158.828 141.517 128.899 1.00 58.38  ? 315 HIS A CD2 1 
ATOM   710  C CE1 . HIS A 1 315 ? 156.830 140.762 129.391 1.00 63.40  ? 315 HIS A CE1 1 
ATOM   711  N NE2 . HIS A 1 315 ? 157.615 141.122 128.392 1.00 64.79  ? 315 HIS A NE2 1 
ATOM   712  N N   . LEU A 1 316 ? 161.456 143.419 133.335 1.00 46.05  ? 316 LEU A N   1 
ATOM   713  C CA  . LEU A 1 316 ? 162.357 143.550 134.474 1.00 41.24  ? 316 LEU A CA  1 
ATOM   714  C C   . LEU A 1 316 ? 161.736 144.406 135.564 1.00 42.89  ? 316 LEU A C   1 
ATOM   715  O O   . LEU A 1 316 ? 161.868 144.100 136.754 1.00 39.59  ? 316 LEU A O   1 
ATOM   716  C CB  . LEU A 1 316 ? 163.692 144.132 134.024 1.00 35.72  ? 316 LEU A CB  1 
ATOM   717  C CG  . LEU A 1 316 ? 164.691 143.103 133.506 1.00 34.60  ? 316 LEU A CG  1 
ATOM   718  C CD1 . LEU A 1 316 ? 165.780 143.778 132.707 1.00 39.77  ? 316 LEU A CD1 1 
ATOM   719  C CD2 . LEU A 1 316 ? 165.281 142.329 134.663 1.00 32.20  ? 316 LEU A CD2 1 
ATOM   720  N N   . PHE A 1 317 ? 161.047 145.481 135.177 1.00 44.85  ? 317 PHE A N   1 
ATOM   721  C CA  . PHE A 1 317 ? 160.338 146.290 136.162 1.00 43.77  ? 317 PHE A CA  1 
ATOM   722  C C   . PHE A 1 317 ? 159.297 145.461 136.900 1.00 45.21  ? 317 PHE A C   1 
ATOM   723  O O   . PHE A 1 317 ? 159.158 145.567 138.123 1.00 48.05  ? 317 PHE A O   1 
ATOM   724  C CB  . PHE A 1 317 ? 159.678 147.486 135.483 1.00 41.93  ? 317 PHE A CB  1 
ATOM   725  C CG  . PHE A 1 317 ? 160.645 148.531 135.019 1.00 43.76  ? 317 PHE A CG  1 
ATOM   726  C CD1 . PHE A 1 317 ? 161.679 148.944 135.835 1.00 41.49  ? 317 PHE A CD1 1 
ATOM   727  C CD2 . PHE A 1 317 ? 160.520 149.100 133.767 1.00 45.50  ? 317 PHE A CD2 1 
ATOM   728  C CE1 . PHE A 1 317 ? 162.566 149.903 135.410 1.00 41.17  ? 317 PHE A CE1 1 
ATOM   729  C CE2 . PHE A 1 317 ? 161.408 150.059 133.338 1.00 42.50  ? 317 PHE A CE2 1 
ATOM   730  C CZ  . PHE A 1 317 ? 162.430 150.460 134.160 1.00 43.13  ? 317 PHE A CZ  1 
ATOM   731  N N   . GLU A 1 318 ? 158.563 144.620 136.168 1.00 42.86  ? 318 GLU A N   1 
ATOM   732  C CA  . GLU A 1 318 ? 157.544 143.780 136.788 1.00 42.25  ? 318 GLU A CA  1 
ATOM   733  C C   . GLU A 1 318 ? 158.156 142.778 137.759 1.00 47.10  ? 318 GLU A C   1 
ATOM   734  O O   . GLU A 1 318 ? 157.639 142.584 138.866 1.00 46.88  ? 318 GLU A O   1 
ATOM   735  C CB  . GLU A 1 318 ? 156.746 143.056 135.708 1.00 39.99  ? 318 GLU A CB  1 
ATOM   736  C CG  . GLU A 1 318 ? 155.711 142.102 136.247 1.00 39.63  ? 318 GLU A CG  1 
ATOM   737  C CD  . GLU A 1 318 ? 155.056 141.289 135.155 1.00 50.98  ? 318 GLU A CD  1 
ATOM   738  O OE1 . GLU A 1 318 ? 155.185 141.666 133.972 1.00 56.67  ? 318 GLU A OE1 1 
ATOM   739  O OE2 . GLU A 1 318 ? 154.416 140.267 135.478 1.00 50.76  ? 318 GLU A OE2 1 
ATOM   740  N N   . ILE A 1 319 ? 159.251 142.126 137.360 1.00 46.49  ? 319 ILE A N   1 
ATOM   741  C CA  . ILE A 1 319 ? 159.896 141.147 138.235 1.00 43.56  ? 319 ILE A CA  1 
ATOM   742  C C   . ILE A 1 319 ? 160.426 141.826 139.489 1.00 45.76  ? 319 ILE A C   1 
ATOM   743  O O   . ILE A 1 319 ? 160.277 141.316 140.607 1.00 44.80  ? 319 ILE A O   1 
ATOM   744  C CB  . ILE A 1 319 ? 161.020 140.405 137.494 1.00 40.82  ? 319 ILE A CB  1 
ATOM   745  C CG1 . ILE A 1 319 ? 160.484 139.740 136.232 1.00 49.23  ? 319 ILE A CG1 1 
ATOM   746  C CG2 . ILE A 1 319 ? 161.639 139.365 138.402 1.00 38.49  ? 319 ILE A CG2 1 
ATOM   747  C CD1 . ILE A 1 319 ? 161.559 139.113 135.373 1.00 48.85  ? 319 ILE A CD1 1 
ATOM   748  N N   . ALA A 1 320 ? 161.066 142.985 139.319 1.00 42.76  ? 320 ALA A N   1 
ATOM   749  C CA  . ALA A 1 320 ? 161.574 143.719 140.469 1.00 41.45  ? 320 ALA A CA  1 
ATOM   750  C C   . ALA A 1 320 ? 160.442 144.123 141.401 1.00 44.14  ? 320 ALA A C   1 
ATOM   751  O O   . ALA A 1 320 ? 160.572 144.016 142.624 1.00 42.89  ? 320 ALA A O   1 
ATOM   752  C CB  . ALA A 1 320 ? 162.354 144.945 140.003 1.00 34.59  ? 320 ALA A CB  1 
ATOM   753  N N   . GLY A 1 321 ? 159.317 144.573 140.841 1.00 44.59  ? 321 GLY A N   1 
ATOM   754  C CA  . GLY A 1 321 ? 158.194 144.958 141.678 1.00 39.97  ? 321 GLY A CA  1 
ATOM   755  C C   . GLY A 1 321 ? 157.612 143.787 142.444 1.00 39.43  ? 321 GLY A C   1 
ATOM   756  O O   . GLY A 1 321 ? 157.311 143.898 143.631 1.00 44.34  ? 321 GLY A O   1 
ATOM   757  N N   . PHE A 1 322 ? 157.450 142.645 141.773 1.00 36.65  ? 322 PHE A N   1 
ATOM   758  C CA  . PHE A 1 322 ? 156.904 141.465 142.440 1.00 38.85  ? 322 PHE A CA  1 
ATOM   759  C C   . PHE A 1 322 ? 157.820 140.990 143.563 1.00 44.76  ? 322 PHE A C   1 
ATOM   760  O O   . PHE A 1 322 ? 157.360 140.704 144.681 1.00 47.07  ? 322 PHE A O   1 
ATOM   761  C CB  . PHE A 1 322 ? 156.681 140.356 141.415 1.00 40.13  ? 322 PHE A CB  1 
ATOM   762  C CG  . PHE A 1 322 ? 156.173 139.077 142.004 1.00 41.03  ? 322 PHE A CG  1 
ATOM   763  C CD1 . PHE A 1 322 ? 154.858 138.966 142.419 1.00 40.03  ? 322 PHE A CD1 1 
ATOM   764  C CD2 . PHE A 1 322 ? 157.003 137.981 142.128 1.00 44.11  ? 322 PHE A CD2 1 
ATOM   765  C CE1 . PHE A 1 322 ? 154.384 137.787 142.957 1.00 39.68  ? 322 PHE A CE1 1 
ATOM   766  C CE2 . PHE A 1 322 ? 156.535 136.798 142.664 1.00 47.79  ? 322 PHE A CE2 1 
ATOM   767  C CZ  . PHE A 1 322 ? 155.223 136.702 143.080 1.00 46.93  ? 322 PHE A CZ  1 
ATOM   768  N N   . LEU A 1 323 ? 159.125 140.912 143.291 1.00 48.49  ? 323 LEU A N   1 
ATOM   769  C CA  . LEU A 1 323 ? 160.062 140.515 144.333 1.00 51.89  ? 323 LEU A CA  1 
ATOM   770  C C   . LEU A 1 323 ? 160.096 141.529 145.467 1.00 47.84  ? 323 LEU A C   1 
ATOM   771  O O   . LEU A 1 323 ? 160.258 141.148 146.630 1.00 44.90  ? 323 LEU A O   1 
ATOM   772  C CB  . LEU A 1 323 ? 161.454 140.319 143.741 1.00 50.57  ? 323 LEU A CB  1 
ATOM   773  C CG  . LEU A 1 323 ? 161.552 139.167 142.745 1.00 57.40  ? 323 LEU A CG  1 
ATOM   774  C CD1 . LEU A 1 323 ? 162.983 138.988 142.274 1.00 60.46  ? 323 LEU A CD1 1 
ATOM   775  C CD2 . LEU A 1 323 ? 161.020 137.890 143.372 1.00 53.90  ? 323 LEU A CD2 1 
ATOM   776  N N   . GLY A 1 324 ? 159.941 142.814 145.154 1.00 45.76  ? 324 GLY A N   1 
ATOM   777  C CA  . GLY A 1 324 ? 159.864 143.809 146.204 1.00 42.67  ? 324 GLY A CA  1 
ATOM   778  C C   . GLY A 1 324 ? 158.621 143.659 147.052 1.00 43.86  ? 324 GLY A C   1 
ATOM   779  O O   . GLY A 1 324 ? 158.655 143.900 148.259 1.00 48.99  ? 324 GLY A O   1 
ATOM   780  N N   . ILE A 1 325 ? 157.506 143.265 146.435 1.00 43.14  ? 325 ILE A N   1 
ATOM   781  C CA  . ILE A 1 325 ? 156.295 142.996 147.206 1.00 42.67  ? 325 ILE A CA  1 
ATOM   782  C C   . ILE A 1 325 ? 156.543 141.857 148.179 1.00 49.83  ? 325 ILE A C   1 
ATOM   783  O O   . ILE A 1 325 ? 156.196 141.941 149.363 1.00 53.63  ? 325 ILE A O   1 
ATOM   784  C CB  . ILE A 1 325 ? 155.110 142.676 146.279 1.00 37.46  ? 325 ILE A CB  1 
ATOM   785  C CG1 . ILE A 1 325 ? 154.813 143.846 145.352 1.00 41.80  ? 325 ILE A CG1 1 
ATOM   786  C CG2 . ILE A 1 325 ? 153.882 142.333 147.101 1.00 35.32  ? 325 ILE A CG2 1 
ATOM   787  C CD1 . ILE A 1 325 ? 154.912 145.169 146.019 1.00 40.81  ? 325 ILE A CD1 1 
ATOM   788  N N   . LEU A 1 326 ? 157.156 140.776 147.692 1.00 50.44  ? 326 LEU A N   1 
ATOM   789  C CA  . LEU A 1 326 ? 157.441 139.642 148.569 1.00 50.18  ? 326 LEU A CA  1 
ATOM   790  C C   . LEU A 1 326 ? 158.389 140.038 149.696 1.00 50.15  ? 326 LEU A C   1 
ATOM   791  O O   . LEU A 1 326 ? 158.175 139.674 150.859 1.00 51.94  ? 326 LEU A O   1 
ATOM   792  C CB  . LEU A 1 326 ? 158.020 138.486 147.759 1.00 42.87  ? 326 LEU A CB  1 
ATOM   793  C CG  . LEU A 1 326 ? 157.101 137.957 146.660 1.00 46.86  ? 326 LEU A CG  1 
ATOM   794  C CD1 . LEU A 1 326 ? 157.668 136.687 146.056 1.00 53.78  ? 326 LEU A CD1 1 
ATOM   795  C CD2 . LEU A 1 326 ? 155.706 137.716 147.202 1.00 47.89  ? 326 LEU A CD2 1 
ATOM   796  N N   . TRP A 1 327 ? 159.433 140.798 149.368 1.00 50.83  ? 327 TRP A N   1 
ATOM   797  C CA  . TRP A 1 327 ? 160.398 141.239 150.368 1.00 51.64  ? 327 TRP A CA  1 
ATOM   798  C C   . TRP A 1 327 ? 159.741 142.120 151.426 1.00 52.80  ? 327 TRP A C   1 
ATOM   799  O O   . TRP A 1 327 ? 159.980 141.948 152.627 1.00 56.09  ? 327 TRP A O   1 
ATOM   800  C CB  . TRP A 1 327 ? 161.535 141.978 149.663 1.00 47.71  ? 327 TRP A CB  1 
ATOM   801  C CG  . TRP A 1 327 ? 162.658 142.409 150.530 1.00 45.69  ? 327 TRP A CG  1 
ATOM   802  C CD1 . TRP A 1 327 ? 163.676 141.635 150.998 1.00 46.05  ? 327 TRP A CD1 1 
ATOM   803  C CD2 . TRP A 1 327 ? 162.905 143.731 151.008 1.00 49.96  ? 327 TRP A CD2 1 
ATOM   804  N NE1 . TRP A 1 327 ? 164.533 142.391 151.756 1.00 49.01  ? 327 TRP A NE1 1 
ATOM   805  C CE2 . TRP A 1 327 ? 164.081 143.683 151.778 1.00 54.33  ? 327 TRP A CE2 1 
ATOM   806  C CE3 . TRP A 1 327 ? 162.240 144.950 150.870 1.00 45.84  ? 327 TRP A CE3 1 
ATOM   807  C CZ2 . TRP A 1 327 ? 164.605 144.807 152.405 1.00 54.91  ? 327 TRP A CZ2 1 
ATOM   808  C CZ3 . TRP A 1 327 ? 162.759 146.061 151.494 1.00 46.21  ? 327 TRP A CZ3 1 
ATOM   809  C CH2 . TRP A 1 327 ? 163.930 145.984 152.252 1.00 53.55  ? 327 TRP A CH2 1 
ATOM   810  N N   . CYS A 1 328 ? 158.900 143.065 151.000 1.00 51.48  ? 328 CYS A N   1 
ATOM   811  C CA  . CYS A 1 328 ? 158.242 143.952 151.951 1.00 48.61  ? 328 CYS A CA  1 
ATOM   812  C C   . CYS A 1 328 ? 157.253 143.195 152.822 1.00 54.76  ? 328 CYS A C   1 
ATOM   813  O O   . CYS A 1 328 ? 157.134 143.478 154.019 1.00 62.40  ? 328 CYS A O   1 
ATOM   814  C CB  . CYS A 1 328 ? 157.543 145.089 151.214 1.00 45.80  ? 328 CYS A CB  1 
ATOM   815  S SG  . CYS A 1 328 ? 158.658 146.377 150.655 1.00 53.13  ? 328 CYS A SG  1 
ATOM   816  N N   . LEU A 1 329 ? 156.523 142.239 152.242 1.00 51.10  ? 329 LEU A N   1 
ATOM   817  C CA  . LEU A 1 329 ? 155.611 141.436 153.048 1.00 54.90  ? 329 LEU A CA  1 
ATOM   818  C C   . LEU A 1 329 ? 156.373 140.626 154.085 1.00 62.44  ? 329 LEU A C   1 
ATOM   819  O O   . LEU A 1 329 ? 155.957 140.542 155.246 1.00 70.28  ? 329 LEU A O   1 
ATOM   820  C CB  . LEU A 1 329 ? 154.779 140.520 152.155 1.00 56.13  ? 329 LEU A CB  1 
ATOM   821  C CG  . LEU A 1 329 ? 153.747 141.218 151.271 1.00 59.11  ? 329 LEU A CG  1 
ATOM   822  C CD1 . LEU A 1 329 ? 152.953 140.202 150.469 1.00 67.81  ? 329 LEU A CD1 1 
ATOM   823  C CD2 . LEU A 1 329 ? 152.829 142.090 152.104 1.00 53.74  ? 329 LEU A CD2 1 
ATOM   824  N N   . SER A 1 330 ? 157.505 140.039 153.691 1.00 58.73  ? 330 SER A N   1 
ATOM   825  C CA  . SER A 1 330 ? 158.314 139.288 154.645 1.00 58.18  ? 330 SER A CA  1 
ATOM   826  C C   . SER A 1 330 ? 158.808 140.185 155.770 1.00 62.03  ? 330 SER A C   1 
ATOM   827  O O   . SER A 1 330 ? 158.749 139.814 156.948 1.00 66.64  ? 330 SER A O   1 
ATOM   828  C CB  . SER A 1 330 ? 159.493 138.634 153.932 1.00 57.57  ? 330 SER A CB  1 
ATOM   829  O OG  . SER A 1 330 ? 160.473 138.232 154.868 1.00 64.83  ? 330 SER A OG  1 
ATOM   830  N N   . LEU A 1 331 ? 159.301 141.375 155.425 1.00 62.52  ? 331 LEU A N   1 
ATOM   831  C CA  . LEU A 1 331 ? 159.828 142.275 156.446 1.00 61.97  ? 331 LEU A CA  1 
ATOM   832  C C   . LEU A 1 331 ? 158.732 142.741 157.397 1.00 71.85  ? 331 LEU A C   1 
ATOM   833  O O   . LEU A 1 331 ? 158.929 142.766 158.620 1.00 77.78  ? 331 LEU A O   1 
ATOM   834  C CB  . LEU A 1 331 ? 160.512 143.465 155.784 1.00 54.69  ? 331 LEU A CB  1 
ATOM   835  C CG  . LEU A 1 331 ? 161.966 143.652 156.198 1.00 57.05  ? 331 LEU A CG  1 
ATOM   836  C CD1 . LEU A 1 331 ? 162.640 144.669 155.310 1.00 57.40  ? 331 LEU A CD1 1 
ATOM   837  C CD2 . LEU A 1 331 ? 162.042 144.079 157.646 1.00 66.07  ? 331 LEU A CD2 1 
ATOM   838  N N   . LEU A 1 332 ? 157.567 143.104 156.856 1.00 73.05  ? 332 LEU A N   1 
ATOM   839  C CA  . LEU A 1 332 ? 156.453 143.516 157.703 1.00 76.52  ? 332 LEU A CA  1 
ATOM   840  C C   . LEU A 1 332 ? 156.015 142.382 158.617 1.00 80.31  ? 332 LEU A C   1 
ATOM   841  O O   . LEU A 1 332 ? 155.711 142.605 159.794 1.00 83.44  ? 332 LEU A O   1 
ATOM   842  C CB  . LEU A 1 332 ? 155.284 143.991 156.840 1.00 66.99  ? 332 LEU A CB  1 
ATOM   843  C CG  . LEU A 1 332 ? 155.440 145.337 156.140 1.00 59.91  ? 332 LEU A CG  1 
ATOM   844  C CD1 . LEU A 1 332 ? 154.414 145.464 155.043 1.00 55.09  ? 332 LEU A CD1 1 
ATOM   845  C CD2 . LEU A 1 332 ? 155.283 146.460 157.139 1.00 64.42  ? 332 LEU A CD2 1 
ATOM   846  N N   . ALA A 1 333 ? 155.975 141.157 158.090 1.00 76.19  ? 333 ALA A N   1 
ATOM   847  C CA  . ALA A 1 333 ? 155.627 140.014 158.922 1.00 80.97  ? 333 ALA A CA  1 
ATOM   848  C C   . ALA A 1 333 ? 156.639 139.830 160.041 1.00 87.44  ? 333 ALA A C   1 
ATOM   849  O O   . ALA A 1 333 ? 156.266 139.563 161.187 1.00 95.97  ? 333 ALA A O   1 
ATOM   850  C CB  . ALA A 1 333 ? 155.535 138.754 158.065 1.00 78.38  ? 333 ALA A CB  1 
ATOM   851  N N   . CYS A 1 334 ? 157.925 139.989 159.730 1.00 84.10  ? 334 CYS A N   1 
ATOM   852  C CA  . CYS A 1 334 ? 158.956 139.825 160.749 1.00 86.16  ? 334 CYS A CA  1 
ATOM   853  C C   . CYS A 1 334 ? 158.856 140.901 161.822 1.00 89.46  ? 334 CYS A C   1 
ATOM   854  O O   . CYS A 1 334 ? 159.156 140.645 162.993 1.00 90.98  ? 334 CYS A O   1 
ATOM   855  C CB  . CYS A 1 334 ? 160.338 139.843 160.105 1.00 80.19  ? 334 CYS A CB  1 
ATOM   856  S SG  . CYS A 1 334 ? 161.684 139.802 161.293 1.00 81.38  ? 334 CYS A SG  1 
ATOM   857  N N   . PHE A 1 335 ? 158.445 142.113 161.441 1.00 90.38  ? 335 PHE A N   1 
ATOM   858  C CA  . PHE A 1 335 ? 158.403 143.210 162.406 1.00 93.03  ? 335 PHE A CA  1 
ATOM   859  C C   . PHE A 1 335 ? 157.409 142.941 163.532 1.00 98.62  ? 335 PHE A C   1 
ATOM   860  O O   . PHE A 1 335 ? 157.708 143.202 164.703 1.00 96.05  ? 335 PHE A O   1 
ATOM   861  C CB  . PHE A 1 335 ? 158.074 144.522 161.699 1.00 87.03  ? 335 PHE A CB  1 
ATOM   862  C CG  . PHE A 1 335 ? 159.281 145.353 161.388 1.00 83.49  ? 335 PHE A CG  1 
ATOM   863  C CD1 . PHE A 1 335 ? 160.541 144.929 161.770 1.00 80.16  ? 335 PHE A CD1 1 
ATOM   864  C CD2 . PHE A 1 335 ? 159.158 146.562 160.730 1.00 85.75  ? 335 PHE A CD2 1 
ATOM   865  C CE1 . PHE A 1 335 ? 161.656 145.689 161.493 1.00 83.44  ? 335 PHE A CE1 1 
ATOM   866  C CE2 . PHE A 1 335 ? 160.273 147.329 160.452 1.00 87.39  ? 335 PHE A CE2 1 
ATOM   867  C CZ  . PHE A 1 335 ? 161.523 146.890 160.833 1.00 87.41  ? 335 PHE A CZ  1 
ATOM   868  N N   . PHE A 1 336 ? 156.226 142.427 163.206 1.00 100.99 ? 336 PHE A N   1 
ATOM   869  C CA  . PHE A 1 336 ? 155.206 142.101 164.202 1.00 102.96 ? 336 PHE A CA  1 
ATOM   870  C C   . PHE A 1 336 ? 154.744 140.657 164.036 1.00 105.99 ? 336 PHE A C   1 
ATOM   871  O O   . PHE A 1 336 ? 153.553 140.360 163.923 1.00 109.32 ? 336 PHE A O   1 
ATOM   872  C CB  . PHE A 1 336 ? 154.022 143.067 164.157 1.00 102.54 ? 336 PHE A CB  1 
ATOM   873  C CG  . PHE A 1 336 ? 153.727 143.622 162.792 1.00 103.65 ? 336 PHE A CG  1 
ATOM   874  C CD1 . PHE A 1 336 ? 153.084 142.853 161.837 1.00 104.63 ? 336 PHE A CD1 1 
ATOM   875  C CD2 . PHE A 1 336 ? 154.064 144.927 162.476 1.00 98.56  ? 336 PHE A CD2 1 
ATOM   876  C CE1 . PHE A 1 336 ? 152.803 143.369 160.588 1.00 100.09 ? 336 PHE A CE1 1 
ATOM   877  C CE2 . PHE A 1 336 ? 153.786 145.446 161.230 1.00 96.47  ? 336 PHE A CE2 1 
ATOM   878  C CZ  . PHE A 1 336 ? 153.155 144.667 160.285 1.00 100.56 ? 336 PHE A CZ  1 
ATOM   879  N N   . ALA A 1 337 ? 155.712 139.735 164.015 1.00 104.35 ? 337 ALA A N   1 
ATOM   880  C CA  . ALA A 1 337 ? 155.526 138.290 163.893 1.00 107.44 ? 337 ALA A CA  1 
ATOM   881  C C   . ALA A 1 337 ? 154.422 137.706 164.773 1.00 115.64 ? 337 ALA A C   1 
ATOM   882  O O   . ALA A 1 337 ? 153.783 136.731 164.359 1.00 117.05 ? 337 ALA A O   1 
ATOM   883  C CB  . ALA A 1 337 ? 156.841 137.571 164.194 1.00 107.25 ? 337 ALA A CB  1 
ATOM   884  N N   . PRO A 1 338 ? 154.155 138.244 165.990 1.00 122.02 ? 338 PRO A N   1 
ATOM   885  C CA  . PRO A 1 338 ? 152.992 137.764 166.756 1.00 124.43 ? 338 PRO A CA  1 
ATOM   886  C C   . PRO A 1 338 ? 151.669 137.802 166.001 1.00 124.72 ? 338 PRO A C   1 
ATOM   887  O O   . PRO A 1 338 ? 150.643 137.365 166.533 1.00 125.11 ? 338 PRO A O   1 
ATOM   888  C CB  . PRO A 1 338 ? 152.969 138.710 167.961 1.00 123.12 ? 338 PRO A CB  1 
ATOM   889  C CG  . PRO A 1 338 ? 154.397 138.972 168.216 1.00 120.03 ? 338 PRO A CG  1 
ATOM   890  C CD  . PRO A 1 338 ? 155.070 139.011 166.861 1.00 119.89 ? 338 PRO A CD  1 
ATOM   891  N N   . ILE A 1 339 ? 151.670 138.330 164.773 1.00 124.45 ? 339 ILE A N   1 
ATOM   892  C CA  . ILE A 1 339 ? 150.499 138.212 163.910 1.00 125.65 ? 339 ILE A CA  1 
ATOM   893  C C   . ILE A 1 339 ? 150.151 136.747 163.682 1.00 124.40 ? 339 ILE A C   1 
ATOM   894  O O   . ILE A 1 339 ? 148.973 136.393 163.545 1.00 126.54 ? 339 ILE A O   1 
ATOM   895  C CB  . ILE A 1 339 ? 150.743 138.955 162.578 1.00 124.76 ? 339 ILE A CB  1 
ATOM   896  C CG1 . ILE A 1 339 ? 149.521 138.852 161.658 1.00 127.34 ? 339 ILE A CG1 1 
ATOM   897  C CG2 . ILE A 1 339 ? 151.991 138.425 161.882 1.00 114.68 ? 339 ILE A CG2 1 
ATOM   898  C CD1 . ILE A 1 339 ? 148.269 139.493 162.219 1.00 119.22 ? 339 ILE A CD1 1 
ATOM   899  N N   . SER A 1 340 ? 151.154 135.873 163.658 1.00 121.41 ? 340 SER A N   1 
ATOM   900  C CA  . SER A 1 340 ? 150.940 134.448 163.463 1.00 121.65 ? 340 SER A CA  1 
ATOM   901  C C   . SER A 1 340 ? 151.786 133.673 164.463 1.00 120.20 ? 340 SER A C   1 
ATOM   902  O O   . SER A 1 340 ? 152.793 134.169 164.973 1.00 118.58 ? 340 SER A O   1 
ATOM   903  C CB  . SER A 1 340 ? 151.276 134.020 162.029 1.00 120.62 ? 340 SER A CB  1 
ATOM   904  O OG  . SER A 1 340 ? 151.010 132.643 161.834 1.00 123.14 ? 340 SER A OG  1 
ATOM   905  N N   . VAL A 1 341 ? 151.361 132.439 164.739 1.00 120.78 ? 341 VAL A N   1 
ATOM   906  C CA  . VAL A 1 341 ? 152.053 131.601 165.712 1.00 116.84 ? 341 VAL A CA  1 
ATOM   907  C C   . VAL A 1 341 ? 153.416 131.135 165.224 1.00 115.35 ? 341 VAL A C   1 
ATOM   908  O O   . VAL A 1 341 ? 154.219 130.647 166.028 1.00 115.93 ? 341 VAL A O   1 
ATOM   909  C CB  . VAL A 1 341 ? 151.176 130.386 166.079 1.00 114.75 ? 341 VAL A CB  1 
ATOM   910  C CG1 . VAL A 1 341 ? 151.228 129.339 164.978 1.00 115.09 ? 341 VAL A CG1 1 
ATOM   911  C CG2 . VAL A 1 341 ? 151.593 129.800 167.423 1.00 113.32 ? 341 VAL A CG2 1 
ATOM   912  N N   . ILE A 1 342 ? 153.703 131.280 163.934 1.00 113.56 ? 342 ILE A N   1 
ATOM   913  C CA  . ILE A 1 342 ? 154.978 130.852 163.365 1.00 114.08 ? 342 ILE A CA  1 
ATOM   914  C C   . ILE A 1 342 ? 156.098 131.711 163.939 1.00 111.08 ? 342 ILE A C   1 
ATOM   915  O O   . ILE A 1 342 ? 155.889 132.902 164.213 1.00 107.83 ? 342 ILE A O   1 
ATOM   916  C CB  . ILE A 1 342 ? 154.952 130.921 161.830 1.00 114.32 ? 342 ILE A CB  1 
ATOM   917  C CG1 . ILE A 1 342 ? 154.482 132.299 161.365 1.00 114.55 ? 342 ILE A CG1 1 
ATOM   918  C CG2 . ILE A 1 342 ? 154.052 129.835 161.263 1.00 113.64 ? 342 ILE A CG2 1 
ATOM   919  C CD1 . ILE A 1 342 ? 154.287 132.397 159.870 1.00 111.63 ? 342 ILE A CD1 1 
ATOM   920  N N   . PRO A 1 343 ? 157.290 131.157 164.145 1.00 109.72 ? 343 PRO A N   1 
ATOM   921  C CA  . PRO A 1 343 ? 158.373 131.933 164.755 1.00 109.65 ? 343 PRO A CA  1 
ATOM   922  C C   . PRO A 1 343 ? 158.821 133.080 163.865 1.00 108.15 ? 343 PRO A C   1 
ATOM   923  O O   . PRO A 1 343 ? 158.650 133.068 162.646 1.00 108.63 ? 343 PRO A O   1 
ATOM   924  C CB  . PRO A 1 343 ? 159.493 130.903 164.933 1.00 112.64 ? 343 PRO A CB  1 
ATOM   925  C CG  . PRO A 1 343 ? 158.807 129.580 164.907 1.00 113.52 ? 343 PRO A CG  1 
ATOM   926  C CD  . PRO A 1 343 ? 157.658 129.744 163.964 1.00 111.78 ? 343 PRO A CD  1 
ATOM   927  N N   . THR A 1 344 ? 159.411 134.089 164.509 1.00 110.28 ? 344 THR A N   1 
ATOM   928  C CA  . THR A 1 344 ? 159.848 135.286 163.801 1.00 109.61 ? 344 THR A CA  1 
ATOM   929  C C   . THR A 1 344 ? 160.939 134.995 162.779 1.00 108.07 ? 344 THR A C   1 
ATOM   930  O O   . THR A 1 344 ? 161.093 135.755 161.818 1.00 101.44 ? 344 THR A O   1 
ATOM   931  C CB  . THR A 1 344 ? 160.344 136.327 164.805 1.00 113.53 ? 344 THR A CB  1 
ATOM   932  O OG1 . THR A 1 344 ? 159.421 136.413 165.897 1.00 122.93 ? 344 THR A OG1 1 
ATOM   933  C CG2 . THR A 1 344 ? 160.470 137.697 164.154 1.00 103.65 ? 344 THR A CG2 1 
ATOM   934  N N   . TYR A 1 345 ? 161.692 133.915 162.952 1.00 111.36 ? 345 TYR A N   1 
ATOM   935  C CA  . TYR A 1 345 ? 162.842 133.641 162.102 1.00 110.28 ? 345 TYR A CA  1 
ATOM   936  C C   . TYR A 1 345 ? 162.515 132.779 160.889 1.00 102.35 ? 345 TYR A C   1 
ATOM   937  O O   . TYR A 1 345 ? 163.433 132.401 160.155 1.00 100.21 ? 345 TYR A O   1 
ATOM   938  C CB  . TYR A 1 345 ? 163.954 132.977 162.920 1.00 114.82 ? 345 TYR A CB  1 
ATOM   939  C CG  . TYR A 1 345 ? 163.488 131.861 163.829 1.00 116.16 ? 345 TYR A CG  1 
ATOM   940  C CD1 . TYR A 1 345 ? 163.107 130.629 163.313 1.00 117.68 ? 345 TYR A CD1 1 
ATOM   941  C CD2 . TYR A 1 345 ? 163.447 132.034 165.205 1.00 121.14 ? 345 TYR A CD2 1 
ATOM   942  C CE1 . TYR A 1 345 ? 162.686 129.610 164.140 1.00 122.45 ? 345 TYR A CE1 1 
ATOM   943  C CE2 . TYR A 1 345 ? 163.029 131.018 166.040 1.00 128.68 ? 345 TYR A CE2 1 
ATOM   944  C CZ  . TYR A 1 345 ? 162.652 129.808 165.502 1.00 129.06 ? 345 TYR A CZ  1 
ATOM   945  O OH  . TYR A 1 345 ? 162.234 128.793 166.330 1.00 134.12 ? 345 TYR A OH  1 
ATOM   946  N N   . VAL A 1 346 ? 161.243 132.453 160.654 1.00 97.60  ? 346 VAL A N   1 
ATOM   947  C CA  . VAL A 1 346 ? 160.885 131.619 159.512 1.00 97.15  ? 346 VAL A CA  1 
ATOM   948  C C   . VAL A 1 346 ? 160.470 132.431 158.296 1.00 92.30  ? 346 VAL A C   1 
ATOM   949  O O   . VAL A 1 346 ? 160.256 131.845 157.222 1.00 91.53  ? 346 VAL A O   1 
ATOM   950  C CB  . VAL A 1 346 ? 159.764 130.620 159.868 1.00 99.45  ? 346 VAL A CB  1 
ATOM   951  C CG1 . VAL A 1 346 ? 160.108 129.867 161.139 1.00 103.78 ? 346 VAL A CG1 1 
ATOM   952  C CG2 . VAL A 1 346 ? 158.437 131.336 160.004 1.00 97.16  ? 346 VAL A CG2 1 
ATOM   953  N N   . TYR A 1 347 ? 160.347 133.756 158.421 1.00 89.26  ? 347 TYR A N   1 
ATOM   954  C CA  . TYR A 1 347 ? 159.914 134.552 157.273 1.00 85.79  ? 347 TYR A CA  1 
ATOM   955  C C   . TYR A 1 347 ? 160.998 134.676 156.209 1.00 82.32  ? 347 TYR A C   1 
ATOM   956  O O   . TYR A 1 347 ? 160.704 134.404 155.031 1.00 77.21  ? 347 TYR A O   1 
ATOM   957  C CB  . TYR A 1 347 ? 159.417 135.920 157.744 1.00 81.48  ? 347 TYR A CB  1 
ATOM   958  C CG  . TYR A 1 347 ? 158.308 135.853 158.763 1.00 84.84  ? 347 TYR A CG  1 
ATOM   959  C CD1 . TYR A 1 347 ? 157.014 135.521 158.391 1.00 84.64  ? 347 TYR A CD1 1 
ATOM   960  C CD2 . TYR A 1 347 ? 158.553 136.130 160.098 1.00 88.44  ? 347 TYR A CD2 1 
ATOM   961  C CE1 . TYR A 1 347 ? 155.998 135.464 159.321 1.00 88.12  ? 347 TYR A CE1 1 
ATOM   962  C CE2 . TYR A 1 347 ? 157.546 136.075 161.035 1.00 91.33  ? 347 TYR A CE2 1 
ATOM   963  C CZ  . TYR A 1 347 ? 156.270 135.742 160.643 1.00 93.35  ? 347 TYR A CZ  1 
ATOM   964  O OH  . TYR A 1 347 ? 155.265 135.686 161.581 1.00 102.74 ? 347 TYR A OH  1 
ATOM   965  N N   . PRO A 1 348 ? 162.237 135.086 156.520 1.00 82.73  ? 348 PRO A N   1 
ATOM   966  C CA  . PRO A 1 348 ? 163.249 135.160 155.452 1.00 75.63  ? 348 PRO A CA  1 
ATOM   967  C C   . PRO A 1 348 ? 163.494 133.829 154.775 1.00 82.01  ? 348 PRO A C   1 
ATOM   968  O O   . PRO A 1 348 ? 163.664 133.784 153.550 1.00 81.53  ? 348 PRO A O   1 
ATOM   969  C CB  . PRO A 1 348 ? 164.502 135.659 156.184 1.00 71.85  ? 348 PRO A CB  1 
ATOM   970  C CG  . PRO A 1 348 ? 163.998 136.303 157.411 1.00 78.32  ? 348 PRO A CG  1 
ATOM   971  C CD  . PRO A 1 348 ? 162.795 135.520 157.813 1.00 85.51  ? 348 PRO A CD  1 
ATOM   972  N N   . LEU A 1 349 ? 163.486 132.735 155.542 1.00 85.63  ? 349 LEU A N   1 
ATOM   973  C CA  . LEU A 1 349 ? 163.697 131.414 154.961 1.00 86.07  ? 349 LEU A CA  1 
ATOM   974  C C   . LEU A 1 349 ? 162.706 131.152 153.839 1.00 83.05  ? 349 LEU A C   1 
ATOM   975  O O   . LEU A 1 349 ? 163.075 130.623 152.785 1.00 79.49  ? 349 LEU A O   1 
ATOM   976  C CB  . LEU A 1 349 ? 163.578 130.338 156.040 1.00 88.67  ? 349 LEU A CB  1 
ATOM   977  C CG  . LEU A 1 349 ? 164.744 130.185 157.016 1.00 92.98  ? 349 LEU A CG  1 
ATOM   978  C CD1 . LEU A 1 349 ? 164.402 129.190 158.111 1.00 97.39  ? 349 LEU A CD1 1 
ATOM   979  C CD2 . LEU A 1 349 ? 165.988 129.746 156.272 1.00 91.16  ? 349 LEU A CD2 1 
ATOM   980  N N   . ALA A 1 350 ? 161.443 131.523 154.045 1.00 80.25  ? 350 ALA A N   1 
ATOM   981  C CA  . ALA A 1 350 ? 160.469 131.433 152.966 1.00 78.74  ? 350 ALA A CA  1 
ATOM   982  C C   . ALA A 1 350 ? 160.857 132.346 151.811 1.00 80.44  ? 350 ALA A C   1 
ATOM   983  O O   . ALA A 1 350 ? 160.982 131.895 150.666 1.00 76.92  ? 350 ALA A O   1 
ATOM   984  C CB  . ALA A 1 350 ? 159.076 131.781 153.488 1.00 76.24  ? 350 ALA A CB  1 
ATOM   985  N N   . LEU A 1 351 ? 161.110 133.625 152.111 1.00 83.28  ? 351 LEU A N   1 
ATOM   986  C CA  . LEU A 1 351 ? 161.347 134.620 151.069 1.00 74.47  ? 351 LEU A CA  1 
ATOM   987  C C   . LEU A 1 351 ? 162.453 134.171 150.128 1.00 70.86  ? 351 LEU A C   1 
ATOM   988  O O   . LEU A 1 351 ? 162.213 133.907 148.944 1.00 73.78  ? 351 LEU A O   1 
ATOM   989  C CB  . LEU A 1 351 ? 161.696 135.967 151.704 1.00 64.94  ? 351 LEU A CB  1 
ATOM   990  C CG  . LEU A 1 351 ? 162.371 136.986 150.786 1.00 54.33  ? 351 LEU A CG  1 
ATOM   991  C CD1 . LEU A 1 351 ? 161.447 137.368 149.654 1.00 57.49  ? 351 LEU A CD1 1 
ATOM   992  C CD2 . LEU A 1 351 ? 162.805 138.213 151.560 1.00 54.97  ? 351 LEU A CD2 1 
ATOM   993  N N   . TYR A 1 352 ? 163.669 134.039 150.656 1.00 66.00  ? 352 TYR A N   1 
ATOM   994  C CA  . TYR A 1 352 ? 164.768 133.553 149.837 1.00 67.34  ? 352 TYR A CA  1 
ATOM   995  C C   . TYR A 1 352 ? 164.439 132.189 149.256 1.00 74.37  ? 352 TYR A C   1 
ATOM   996  O O   . TYR A 1 352 ? 164.699 131.935 148.073 1.00 78.65  ? 352 TYR A O   1 
ATOM   997  C CB  . TYR A 1 352 ? 166.051 133.518 150.660 1.00 65.88  ? 352 TYR A CB  1 
ATOM   998  C CG  . TYR A 1 352 ? 166.485 134.896 151.086 1.00 68.10  ? 352 TYR A CG  1 
ATOM   999  C CD1 . TYR A 1 352 ? 166.263 135.991 150.265 1.00 64.14  ? 352 TYR A CD1 1 
ATOM   1000 C CD2 . TYR A 1 352 ? 167.094 135.109 152.310 1.00 74.81  ? 352 TYR A CD2 1 
ATOM   1001 C CE1 . TYR A 1 352 ? 166.648 137.254 150.643 1.00 61.44  ? 352 TYR A CE1 1 
ATOM   1002 C CE2 . TYR A 1 352 ? 167.483 136.374 152.699 1.00 72.82  ? 352 TYR A CE2 1 
ATOM   1003 C CZ  . TYR A 1 352 ? 167.255 137.442 151.861 1.00 63.73  ? 352 TYR A CZ  1 
ATOM   1004 O OH  . TYR A 1 352 ? 167.641 138.703 152.242 1.00 59.74  ? 352 TYR A OH  1 
ATOM   1005 N N   . GLY A 1 353 ? 163.815 131.318 150.053 1.00 70.89  ? 353 GLY A N   1 
ATOM   1006 C CA  . GLY A 1 353 ? 163.344 130.059 149.505 1.00 71.47  ? 353 GLY A CA  1 
ATOM   1007 C C   . GLY A 1 353 ? 162.431 130.280 148.319 1.00 76.57  ? 353 GLY A C   1 
ATOM   1008 O O   . GLY A 1 353 ? 162.680 129.770 147.222 1.00 75.48  ? 353 GLY A O   1 
ATOM   1009 N N   . PHE A 1 354 ? 161.404 131.116 148.503 1.00 78.56  ? 354 PHE A N   1 
ATOM   1010 C CA  . PHE A 1 354 ? 160.560 131.503 147.380 1.00 75.64  ? 354 PHE A CA  1 
ATOM   1011 C C   . PHE A 1 354 ? 161.408 132.072 146.255 1.00 71.25  ? 354 PHE A C   1 
ATOM   1012 O O   . PHE A 1 354 ? 161.248 131.685 145.091 1.00 70.78  ? 354 PHE A O   1 
ATOM   1013 C CB  . PHE A 1 354 ? 159.514 132.519 147.838 1.00 76.40  ? 354 PHE A CB  1 
ATOM   1014 C CG  . PHE A 1 354 ? 158.289 132.575 146.967 1.00 78.02  ? 354 PHE A CG  1 
ATOM   1015 C CD1 . PHE A 1 354 ? 158.393 132.725 145.596 1.00 77.06  ? 354 PHE A CD1 1 
ATOM   1016 C CD2 . PHE A 1 354 ? 157.028 132.475 147.529 1.00 77.11  ? 354 PHE A CD2 1 
ATOM   1017 C CE1 . PHE A 1 354 ? 157.268 132.776 144.801 1.00 76.70  ? 354 PHE A CE1 1 
ATOM   1018 C CE2 . PHE A 1 354 ? 155.899 132.524 146.740 1.00 79.49  ? 354 PHE A CE2 1 
ATOM   1019 C CZ  . PHE A 1 354 ? 156.019 132.675 145.374 1.00 81.52  ? 354 PHE A CZ  1 
ATOM   1020 N N   . MET A 1 355 ? 162.350 132.954 146.596 1.00 70.83  ? 355 MET A N   1 
ATOM   1021 C CA  . MET A 1 355 ? 163.258 133.509 145.605 1.00 69.58  ? 355 MET A CA  1 
ATOM   1022 C C   . MET A 1 355 ? 163.930 132.384 144.836 1.00 75.56  ? 355 MET A C   1 
ATOM   1023 O O   . MET A 1 355 ? 163.875 132.337 143.602 1.00 77.74  ? 355 MET A O   1 
ATOM   1024 C CB  . MET A 1 355 ? 164.296 134.397 146.294 1.00 70.94  ? 355 MET A CB  1 
ATOM   1025 C CG  . MET A 1 355 ? 165.014 135.352 145.367 1.00 69.29  ? 355 MET A CG  1 
ATOM   1026 S SD  . MET A 1 355 ? 164.043 136.819 144.993 1.00 71.37  ? 355 MET A SD  1 
ATOM   1027 C CE  . MET A 1 355 ? 163.923 137.566 146.614 1.00 64.97  ? 355 MET A CE  1 
ATOM   1028 N N   . VAL A 1 356 ? 164.514 131.429 145.564 1.00 76.76  ? 356 VAL A N   1 
ATOM   1029 C CA  . VAL A 1 356 ? 165.140 130.292 144.900 1.00 76.84  ? 356 VAL A CA  1 
ATOM   1030 C C   . VAL A 1 356 ? 164.096 129.509 144.121 1.00 82.09  ? 356 VAL A C   1 
ATOM   1031 O O   . VAL A 1 356 ? 164.318 129.127 142.965 1.00 81.09  ? 356 VAL A O   1 
ATOM   1032 C CB  . VAL A 1 356 ? 165.877 129.403 145.917 1.00 75.34  ? 356 VAL A CB  1 
ATOM   1033 C CG1 . VAL A 1 356 ? 166.462 128.191 145.218 1.00 74.81  ? 356 VAL A CG1 1 
ATOM   1034 C CG2 . VAL A 1 356 ? 166.971 130.189 146.613 1.00 74.59  ? 356 VAL A CG2 1 
ATOM   1035 N N   . PHE A 1 357 ? 162.925 129.291 144.727 1.00 81.75  ? 357 PHE A N   1 
ATOM   1036 C CA  . PHE A 1 357 ? 161.855 128.596 144.025 1.00 79.03  ? 357 PHE A CA  1 
ATOM   1037 C C   . PHE A 1 357 ? 161.408 129.355 142.788 1.00 77.84  ? 357 PHE A C   1 
ATOM   1038 O O   . PHE A 1 357 ? 160.909 128.737 141.842 1.00 76.94  ? 357 PHE A O   1 
ATOM   1039 C CB  . PHE A 1 357 ? 160.667 128.365 144.959 1.00 75.58  ? 357 PHE A CB  1 
ATOM   1040 C CG  . PHE A 1 357 ? 160.920 127.330 146.017 1.00 78.44  ? 357 PHE A CG  1 
ATOM   1041 C CD1 . PHE A 1 357 ? 161.990 126.459 145.913 1.00 81.15  ? 357 PHE A CD1 1 
ATOM   1042 C CD2 . PHE A 1 357 ? 160.082 127.225 147.115 1.00 83.01  ? 357 PHE A CD2 1 
ATOM   1043 C CE1 . PHE A 1 357 ? 162.224 125.505 146.885 1.00 84.85  ? 357 PHE A CE1 1 
ATOM   1044 C CE2 . PHE A 1 357 ? 160.311 126.271 148.091 1.00 84.85  ? 357 PHE A CE2 1 
ATOM   1045 C CZ  . PHE A 1 357 ? 161.383 125.411 147.975 1.00 85.22  ? 357 PHE A CZ  1 
ATOM   1046 N N   . PHE A 1 358 ? 161.580 130.677 142.766 1.00 77.78  ? 358 PHE A N   1 
ATOM   1047 C CA  . PHE A 1 358 ? 161.276 131.413 141.548 1.00 75.33  ? 358 PHE A CA  1 
ATOM   1048 C C   . PHE A 1 358 ? 162.374 131.226 140.511 1.00 73.26  ? 358 PHE A C   1 
ATOM   1049 O O   . PHE A 1 358 ? 162.091 131.156 139.312 1.00 70.99  ? 358 PHE A O   1 
ATOM   1050 C CB  . PHE A 1 358 ? 161.072 132.895 141.860 1.00 73.67  ? 358 PHE A CB  1 
ATOM   1051 C CG  . PHE A 1 358 ? 160.577 133.696 140.692 1.00 69.93  ? 358 PHE A CG  1 
ATOM   1052 C CD1 . PHE A 1 358 ? 159.284 133.538 140.226 1.00 68.87  ? 358 PHE A CD1 1 
ATOM   1053 C CD2 . PHE A 1 358 ? 161.400 134.614 140.066 1.00 71.80  ? 358 PHE A CD2 1 
ATOM   1054 C CE1 . PHE A 1 358 ? 158.824 134.275 139.153 1.00 70.70  ? 358 PHE A CE1 1 
ATOM   1055 C CE2 . PHE A 1 358 ? 160.945 135.354 138.993 1.00 67.73  ? 358 PHE A CE2 1 
ATOM   1056 C CZ  . PHE A 1 358 ? 159.656 135.184 138.537 1.00 66.31  ? 358 PHE A CZ  1 
ATOM   1057 N N   . LEU A 1 359 ? 163.630 131.127 140.954 1.00 73.42  ? 359 LEU A N   1 
ATOM   1058 C CA  . LEU A 1 359 ? 164.728 130.950 140.011 1.00 72.56  ? 359 LEU A CA  1 
ATOM   1059 C C   . LEU A 1 359 ? 164.676 129.576 139.358 1.00 75.75  ? 359 LEU A C   1 
ATOM   1060 O O   . LEU A 1 359 ? 164.777 129.457 138.132 1.00 73.24  ? 359 LEU A O   1 
ATOM   1061 C CB  . LEU A 1 359 ? 166.069 131.157 140.712 1.00 70.13  ? 359 LEU A CB  1 
ATOM   1062 C CG  . LEU A 1 359 ? 167.271 130.856 139.817 1.00 74.17  ? 359 LEU A CG  1 
ATOM   1063 C CD1 . LEU A 1 359 ? 167.294 131.808 138.632 1.00 68.92  ? 359 LEU A CD1 1 
ATOM   1064 C CD2 . LEU A 1 359 ? 168.578 130.918 140.593 1.00 73.46  ? 359 LEU A CD2 1 
ATOM   1065 N N   . ILE A 1 360 ? 164.520 128.526 140.157 1.00 78.47  ? 360 ILE A N   1 
ATOM   1066 C CA  . ILE A 1 360 ? 164.436 127.164 139.646 1.00 77.81  ? 360 ILE A CA  1 
ATOM   1067 C C   . ILE A 1 360 ? 162.978 126.727 139.726 1.00 83.28  ? 360 ILE A C   1 
ATOM   1068 O O   . ILE A 1 360 ? 162.413 126.568 140.814 1.00 81.57  ? 360 ILE A O   1 
ATOM   1069 C CB  . ILE A 1 360 ? 165.369 126.205 140.402 1.00 77.90  ? 360 ILE A CB  1 
ATOM   1070 C CG1 . ILE A 1 360 ? 165.170 124.773 139.905 1.00 84.09  ? 360 ILE A CG1 1 
ATOM   1071 C CG2 . ILE A 1 360 ? 165.188 126.306 141.915 1.00 74.77  ? 360 ILE A CG2 1 
ATOM   1072 C CD1 . ILE A 1 360 ? 165.458 124.598 138.424 1.00 81.18  ? 360 ILE A CD1 1 
ATOM   1073 N N   . ASN A 1 361 ? 162.364 126.552 138.568 1.00 84.22  ? 361 ASN A N   1 
ATOM   1074 C CA  . ASN A 1 361 ? 160.977 126.133 138.461 1.00 81.45  ? 361 ASN A CA  1 
ATOM   1075 C C   . ASN A 1 361 ? 160.798 125.481 137.098 1.00 84.38  ? 361 ASN A C   1 
ATOM   1076 O O   . ASN A 1 361 ? 160.695 126.183 136.084 1.00 83.72  ? 361 ASN A O   1 
ATOM   1077 C CB  . ASN A 1 361 ? 160.033 127.322 138.642 1.00 78.59  ? 361 ASN A CB  1 
ATOM   1078 C CG  . ASN A 1 361 ? 158.613 126.899 138.944 1.00 83.45  ? 361 ASN A CG  1 
ATOM   1079 O OD1 . ASN A 1 361 ? 158.205 125.782 138.629 1.00 82.96  ? 361 ASN A OD1 1 
ATOM   1080 N ND2 . ASN A 1 361 ? 157.849 127.794 139.558 1.00 82.81  ? 361 ASN A ND2 1 
ATOM   1081 N N   . PRO A 1 362 ? 160.785 124.148 137.029 1.00 88.02  ? 362 PRO A N   1 
ATOM   1082 C CA  . PRO A 1 362 ? 160.773 123.481 135.716 1.00 86.45  ? 362 PRO A CA  1 
ATOM   1083 C C   . PRO A 1 362 ? 159.553 123.803 134.872 1.00 85.11  ? 362 PRO A C   1 
ATOM   1084 O O   . PRO A 1 362 ? 159.638 123.760 133.638 1.00 79.50  ? 362 PRO A O   1 
ATOM   1085 C CB  . PRO A 1 362 ? 160.833 121.993 136.083 1.00 90.61  ? 362 PRO A CB  1 
ATOM   1086 C CG  . PRO A 1 362 ? 160.304 121.925 137.479 1.00 91.68  ? 362 PRO A CG  1 
ATOM   1087 C CD  . PRO A 1 362 ? 160.740 123.189 138.144 1.00 87.89  ? 362 PRO A CD  1 
ATOM   1088 N N   . THR A 1 363 ? 158.423 124.122 135.495 1.00 86.92  ? 363 THR A N   1 
ATOM   1089 C CA  . THR A 1 363 ? 157.221 124.453 134.743 1.00 84.84  ? 363 THR A CA  1 
ATOM   1090 C C   . THR A 1 363 ? 157.430 125.747 133.969 1.00 80.03  ? 363 THR A C   1 
ATOM   1091 O O   . THR A 1 363 ? 157.941 126.731 134.510 1.00 80.28  ? 363 THR A O   1 
ATOM   1092 C CB  . THR A 1 363 ? 156.030 124.592 135.686 1.00 90.48  ? 363 THR A CB  1 
ATOM   1093 O OG1 . THR A 1 363 ? 156.217 125.742 136.517 1.00 93.96  ? 363 THR A OG1 1 
ATOM   1094 C CG2 . THR A 1 363 ? 155.909 123.363 136.570 1.00 90.56  ? 363 THR A CG2 1 
ATOM   1095 N N   . LYS A 1 364 ? 157.022 125.751 132.700 1.00 78.75  ? 364 LYS A N   1 
ATOM   1096 C CA  . LYS A 1 364 ? 157.205 126.914 131.834 1.00 81.67  ? 364 LYS A CA  1 
ATOM   1097 C C   . LYS A 1 364 ? 156.098 127.932 132.113 1.00 86.19  ? 364 LYS A C   1 
ATOM   1098 O O   . LYS A 1 364 ? 155.162 128.122 131.334 1.00 90.24  ? 364 LYS A O   1 
ATOM   1099 C CB  . LYS A 1 364 ? 157.215 126.495 130.371 1.00 78.61  ? 364 LYS A CB  1 
ATOM   1100 C CG  . LYS A 1 364 ? 158.046 125.263 130.075 1.00 81.59  ? 364 LYS A CG  1 
ATOM   1101 C CD  . LYS A 1 364 ? 158.034 124.951 128.590 1.00 79.34  ? 364 LYS A CD  1 
ATOM   1102 C CE  . LYS A 1 364 ? 158.693 123.615 128.304 1.00 78.71  ? 364 LYS A CE  1 
ATOM   1103 N NZ  . LYS A 1 364 ? 160.094 123.573 128.798 1.00 81.99  ? 364 LYS A NZ  1 
ATOM   1104 N N   . THR A 1 365 ? 156.222 128.604 133.257 1.00 85.19  ? 365 THR A N   1 
ATOM   1105 C CA  . THR A 1 365 ? 155.180 129.519 133.711 1.00 87.33  ? 365 THR A CA  1 
ATOM   1106 C C   . THR A 1 365 ? 155.639 130.971 133.751 1.00 84.80  ? 365 THR A C   1 
ATOM   1107 O O   . THR A 1 365 ? 155.070 131.807 133.043 1.00 84.96  ? 365 THR A O   1 
ATOM   1108 C CB  . THR A 1 365 ? 154.673 129.083 135.091 1.00 87.46  ? 365 THR A CB  1 
ATOM   1109 O OG1 . THR A 1 365 ? 155.778 128.991 135.999 1.00 88.10  ? 365 THR A OG1 1 
ATOM   1110 C CG2 . THR A 1 365 ? 153.984 127.733 135.003 1.00 83.80  ? 365 THR A CG2 1 
ATOM   1111 N N   . PHE A 1 366 ? 156.658 131.301 134.540 1.00 81.33  ? 366 PHE A N   1 
ATOM   1112 C CA  . PHE A 1 366 ? 157.009 132.692 134.830 1.00 77.66  ? 366 PHE A CA  1 
ATOM   1113 C C   . PHE A 1 366 ? 158.360 133.005 134.193 1.00 74.71  ? 366 PHE A C   1 
ATOM   1114 O O   . PHE A 1 366 ? 159.408 132.788 134.800 1.00 73.69  ? 366 PHE A O   1 
ATOM   1115 C CB  . PHE A 1 366 ? 157.045 132.941 136.337 1.00 76.64  ? 366 PHE A CB  1 
ATOM   1116 C CG  . PHE A 1 366 ? 155.705 132.835 137.011 1.00 80.14  ? 366 PHE A CG  1 
ATOM   1117 C CD1 . PHE A 1 366 ? 154.539 132.796 136.272 1.00 79.81  ? 366 PHE A CD1 1 
ATOM   1118 C CD2 . PHE A 1 366 ? 155.617 132.791 138.393 1.00 81.36  ? 366 PHE A CD2 1 
ATOM   1119 C CE1 . PHE A 1 366 ? 153.312 132.701 136.896 1.00 78.87  ? 366 PHE A CE1 1 
ATOM   1120 C CE2 . PHE A 1 366 ? 154.391 132.700 139.022 1.00 79.58  ? 366 PHE A CE2 1 
ATOM   1121 C CZ  . PHE A 1 366 ? 153.238 132.656 138.272 1.00 76.78  ? 366 PHE A CZ  1 
ATOM   1122 N N   . TYR A 1 367 ? 158.324 133.543 132.973 1.00 71.29  ? 367 TYR A N   1 
ATOM   1123 C CA  . TYR A 1 367 ? 159.530 133.869 132.212 1.00 69.60  ? 367 TYR A CA  1 
ATOM   1124 C C   . TYR A 1 367 ? 160.453 132.659 132.104 1.00 69.35  ? 367 TYR A C   1 
ATOM   1125 O O   . TYR A 1 367 ? 161.617 132.699 132.505 1.00 70.88  ? 367 TYR A O   1 
ATOM   1126 C CB  . TYR A 1 367 ? 160.276 135.049 132.833 1.00 65.64  ? 367 TYR A CB  1 
ATOM   1127 C CG  . TYR A 1 367 ? 159.437 136.273 133.067 1.00 58.34  ? 367 TYR A CG  1 
ATOM   1128 C CD1 . TYR A 1 367 ? 159.124 137.127 132.026 1.00 61.46  ? 367 TYR A CD1 1 
ATOM   1129 C CD2 . TYR A 1 367 ? 158.978 136.588 134.334 1.00 56.47  ? 367 TYR A CD2 1 
ATOM   1130 C CE1 . TYR A 1 367 ? 158.366 138.251 132.238 1.00 61.70  ? 367 TYR A CE1 1 
ATOM   1131 C CE2 . TYR A 1 367 ? 158.220 137.709 134.554 1.00 60.06  ? 367 TYR A CE2 1 
ATOM   1132 C CZ  . TYR A 1 367 ? 157.917 138.538 133.502 1.00 60.52  ? 367 TYR A CZ  1 
ATOM   1133 O OH  . TYR A 1 367 ? 157.158 139.662 133.705 1.00 60.67  ? 367 TYR A OH  1 
ATOM   1134 N N   . TYR A 1 368 ? 159.919 131.563 131.567 1.00 69.03  ? 368 TYR A N   1 
ATOM   1135 C CA  . TYR A 1 368 ? 160.684 130.323 131.557 1.00 68.79  ? 368 TYR A CA  1 
ATOM   1136 C C   . TYR A 1 368 ? 161.948 130.458 130.720 1.00 71.87  ? 368 TYR A C   1 
ATOM   1137 O O   . TYR A 1 368 ? 163.020 130.005 131.132 1.00 77.13  ? 368 TYR A O   1 
ATOM   1138 C CB  . TYR A 1 368 ? 159.819 129.160 131.069 1.00 76.25  ? 368 TYR A CB  1 
ATOM   1139 C CG  . TYR A 1 368 ? 159.368 129.233 129.627 1.00 79.27  ? 368 TYR A CG  1 
ATOM   1140 C CD1 . TYR A 1 368 ? 158.361 130.101 129.236 1.00 80.44  ? 368 TYR A CD1 1 
ATOM   1141 C CD2 . TYR A 1 368 ? 159.925 128.402 128.666 1.00 76.75  ? 368 TYR A CD2 1 
ATOM   1142 C CE1 . TYR A 1 368 ? 157.941 130.159 127.925 1.00 76.79  ? 368 TYR A CE1 1 
ATOM   1143 C CE2 . TYR A 1 368 ? 159.511 128.451 127.356 1.00 75.10  ? 368 TYR A CE2 1 
ATOM   1144 C CZ  . TYR A 1 368 ? 158.519 129.331 126.990 1.00 72.95  ? 368 TYR A CZ  1 
ATOM   1145 O OH  . TYR A 1 368 ? 158.105 129.382 125.680 1.00 70.88  ? 368 TYR A OH  1 
ATOM   1146 N N   . LYS A 1 369 ? 161.852 131.098 129.555 1.00 72.55  ? 369 LYS A N   1 
ATOM   1147 C CA  . LYS A 1 369 ? 163.042 131.283 128.732 1.00 72.12  ? 369 LYS A CA  1 
ATOM   1148 C C   . LYS A 1 369 ? 164.094 132.096 129.472 1.00 71.09  ? 369 LYS A C   1 
ATOM   1149 O O   . LYS A 1 369 ? 165.276 131.735 129.491 1.00 67.90  ? 369 LYS A O   1 
ATOM   1150 C CB  . LYS A 1 369 ? 162.672 131.954 127.412 1.00 73.49  ? 369 LYS A CB  1 
ATOM   1151 C CG  . LYS A 1 369 ? 162.018 131.023 126.416 1.00 75.23  ? 369 LYS A CG  1 
ATOM   1152 C CD  . LYS A 1 369 ? 161.770 131.717 125.092 1.00 82.23  ? 369 LYS A CD  1 
ATOM   1153 C CE  . LYS A 1 369 ? 161.134 130.767 124.091 1.00 80.56  ? 369 LYS A CE  1 
ATOM   1154 N NZ  . LYS A 1 369 ? 160.829 131.445 122.803 1.00 75.97  ? 369 LYS A NZ  1 
ATOM   1155 N N   . SER A 1 370 ? 163.675 133.194 130.105 1.00 72.64  ? 370 SER A N   1 
ATOM   1156 C CA  . SER A 1 370 ? 164.623 134.054 130.803 1.00 67.38  ? 370 SER A CA  1 
ATOM   1157 C C   . SER A 1 370 ? 165.268 133.334 131.977 1.00 65.10  ? 370 SER A C   1 
ATOM   1158 O O   . SER A 1 370 ? 166.489 133.392 132.153 1.00 72.56  ? 370 SER A O   1 
ATOM   1159 C CB  . SER A 1 370 ? 163.921 135.324 131.277 1.00 63.41  ? 370 SER A CB  1 
ATOM   1160 O OG  . SER A 1 370 ? 163.438 136.066 130.175 1.00 72.27  ? 370 SER A OG  1 
ATOM   1161 N N   . ARG A 1 371 ? 164.469 132.646 132.791 1.00 59.45  ? 371 ARG A N   1 
ATOM   1162 C CA  . ARG A 1 371 ? 165.026 131.958 133.950 1.00 58.13  ? 371 ARG A CA  1 
ATOM   1163 C C   . ARG A 1 371 ? 165.952 130.825 133.530 1.00 63.53  ? 371 ARG A C   1 
ATOM   1164 O O   . ARG A 1 371 ? 166.990 130.600 134.160 1.00 62.98  ? 371 ARG A O   1 
ATOM   1165 C CB  . ARG A 1 371 ? 163.906 131.434 134.842 1.00 66.48  ? 371 ARG A CB  1 
ATOM   1166 C CG  . ARG A 1 371 ? 163.104 132.522 135.518 1.00 68.91  ? 371 ARG A CG  1 
ATOM   1167 C CD  . ARG A 1 371 ? 161.990 131.944 136.369 1.00 69.15  ? 371 ARG A CD  1 
ATOM   1168 N NE  . ARG A 1 371 ? 160.965 131.280 135.573 1.00 68.89  ? 371 ARG A NE  1 
ATOM   1169 C CZ  . ARG A 1 371 ? 160.872 129.968 135.412 1.00 72.91  ? 371 ARG A CZ  1 
ATOM   1170 N NH1 . ARG A 1 371 ? 161.728 129.140 135.983 1.00 75.25  ? 371 ARG A NH1 1 
ATOM   1171 N NH2 . ARG A 1 371 ? 159.892 129.476 134.661 1.00 75.74  ? 371 ARG A NH2 1 
ATOM   1172 N N   . PHE A 1 372 ? 165.595 130.093 132.472 1.00 68.16  ? 372 PHE A N   1 
ATOM   1173 C CA  . PHE A 1 372 ? 166.450 129.003 132.013 1.00 66.22  ? 372 PHE A CA  1 
ATOM   1174 C C   . PHE A 1 372 ? 167.759 129.530 131.436 1.00 66.91  ? 372 PHE A C   1 
ATOM   1175 O O   . PHE A 1 372 ? 168.828 128.954 131.679 1.00 66.53  ? 372 PHE A O   1 
ATOM   1176 C CB  . PHE A 1 372 ? 165.704 128.146 130.989 1.00 66.00  ? 372 PHE A CB  1 
ATOM   1177 C CG  . PHE A 1 372 ? 164.507 127.432 131.556 1.00 70.81  ? 372 PHE A CG  1 
ATOM   1178 C CD1 . PHE A 1 372 ? 164.392 127.222 132.919 1.00 69.81  ? 372 PHE A CD1 1 
ATOM   1179 C CD2 . PHE A 1 372 ? 163.497 126.975 130.727 1.00 72.58  ? 372 PHE A CD2 1 
ATOM   1180 C CE1 . PHE A 1 372 ? 163.296 126.573 133.443 1.00 72.21  ? 372 PHE A CE1 1 
ATOM   1181 C CE2 . PHE A 1 372 ? 162.398 126.324 131.249 1.00 73.68  ? 372 PHE A CE2 1 
ATOM   1182 C CZ  . PHE A 1 372 ? 162.299 126.124 132.608 1.00 76.21  ? 372 PHE A CZ  1 
ATOM   1183 N N   . TRP A 1 373 ? 167.698 130.626 130.674 1.00 66.26  ? 373 TRP A N   1 
ATOM   1184 C CA  . TRP A 1 373 ? 168.917 131.254 130.176 1.00 62.81  ? 373 TRP A CA  1 
ATOM   1185 C C   . TRP A 1 373 ? 169.798 131.721 131.324 1.00 57.88  ? 373 TRP A C   1 
ATOM   1186 O O   . TRP A 1 373 ? 171.020 131.530 131.301 1.00 57.91  ? 373 TRP A O   1 
ATOM   1187 C CB  . TRP A 1 373 ? 168.554 132.425 129.268 1.00 64.06  ? 373 TRP A CB  1 
ATOM   1188 C CG  . TRP A 1 373 ? 169.717 133.136 128.666 1.00 64.81  ? 373 TRP A CG  1 
ATOM   1189 C CD1 . TRP A 1 373 ? 170.365 132.813 127.512 1.00 72.20  ? 373 TRP A CD1 1 
ATOM   1190 C CD2 . TRP A 1 373 ? 170.355 134.313 129.168 1.00 65.59  ? 373 TRP A CD2 1 
ATOM   1191 N NE1 . TRP A 1 373 ? 171.376 133.709 127.270 1.00 78.23  ? 373 TRP A NE1 1 
ATOM   1192 C CE2 . TRP A 1 373 ? 171.390 134.641 128.273 1.00 67.43  ? 373 TRP A CE2 1 
ATOM   1193 C CE3 . TRP A 1 373 ? 170.155 135.119 130.289 1.00 65.98  ? 373 TRP A CE3 1 
ATOM   1194 C CZ2 . TRP A 1 373 ? 172.223 135.737 128.466 1.00 62.92  ? 373 TRP A CZ2 1 
ATOM   1195 C CZ3 . TRP A 1 373 ? 170.983 136.205 130.479 1.00 64.97  ? 373 TRP A CZ3 1 
ATOM   1196 C CH2 . TRP A 1 373 ? 172.003 136.505 129.573 1.00 64.43  ? 373 TRP A CH2 1 
ATOM   1197 N N   . LEU A 1 374 ? 169.189 132.324 132.347 1.00 57.96  ? 374 LEU A N   1 
ATOM   1198 C CA  . LEU A 1 374 ? 169.955 132.766 133.505 1.00 53.38  ? 374 LEU A CA  1 
ATOM   1199 C C   . LEU A 1 374 ? 170.567 131.585 134.243 1.00 58.18  ? 374 LEU A C   1 
ATOM   1200 O O   . LEU A 1 374 ? 171.682 131.684 134.756 1.00 62.03  ? 374 LEU A O   1 
ATOM   1201 C CB  . LEU A 1 374 ? 169.074 133.581 134.446 1.00 45.89  ? 374 LEU A CB  1 
ATOM   1202 C CG  . LEU A 1 374 ? 169.829 134.105 135.664 1.00 39.61  ? 374 LEU A CG  1 
ATOM   1203 C CD1 . LEU A 1 374 ? 170.878 135.097 135.220 1.00 45.81  ? 374 LEU A CD1 1 
ATOM   1204 C CD2 . LEU A 1 374 ? 168.889 134.728 136.672 1.00 44.62  ? 374 LEU A CD2 1 
ATOM   1205 N N   . LEU A 1 375 ? 169.847 130.466 134.331 1.00 57.67  ? 375 LEU A N   1 
ATOM   1206 C CA  . LEU A 1 375 ? 170.396 129.293 135.004 1.00 57.39  ? 375 LEU A CA  1 
ATOM   1207 C C   . LEU A 1 375 ? 171.580 128.715 134.240 1.00 57.55  ? 375 LEU A C   1 
ATOM   1208 O O   . LEU A 1 375 ? 172.598 128.353 134.842 1.00 55.69  ? 375 LEU A O   1 
ATOM   1209 C CB  . LEU A 1 375 ? 169.310 128.237 135.195 1.00 57.07  ? 375 LEU A CB  1 
ATOM   1210 C CG  . LEU A 1 375 ? 168.459 128.400 136.452 1.00 61.83  ? 375 LEU A CG  1 
ATOM   1211 C CD1 . LEU A 1 375 ? 167.423 127.297 136.542 1.00 71.68  ? 375 LEU A CD1 1 
ATOM   1212 C CD2 . LEU A 1 375 ? 169.342 128.410 137.686 1.00 62.80  ? 375 LEU A CD2 1 
ATOM   1213 N N   . LYS A 1 376 ? 171.466 128.623 132.914 1.00 57.17  ? 376 LYS A N   1 
ATOM   1214 C CA  . LYS A 1 376 ? 172.601 128.171 132.117 1.00 57.95  ? 376 LYS A CA  1 
ATOM   1215 C C   . LYS A 1 376 ? 173.794 129.100 132.295 1.00 59.84  ? 376 LYS A C   1 
ATOM   1216 O O   . LYS A 1 376 ? 174.932 128.643 132.462 1.00 62.95  ? 376 LYS A O   1 
ATOM   1217 C CB  . LYS A 1 376 ? 172.214 128.078 130.640 1.00 58.99  ? 376 LYS A CB  1 
ATOM   1218 C CG  . LYS A 1 376 ? 171.774 126.694 130.181 1.00 68.23  ? 376 LYS A CG  1 
ATOM   1219 C CD  . LYS A 1 376 ? 170.414 126.306 130.739 1.00 68.33  ? 376 LYS A CD  1 
ATOM   1220 C CE  . LYS A 1 376 ? 169.992 124.926 130.252 1.00 72.80  ? 376 LYS A CE  1 
ATOM   1221 N NZ  . LYS A 1 376 ? 168.611 124.560 130.678 1.00 70.71  ? 376 LYS A NZ  1 
ATOM   1222 N N   . LEU A 1 377 ? 173.549 130.412 132.279 1.00 58.82  ? 377 LEU A N   1 
ATOM   1223 C CA  . LEU A 1 377 ? 174.635 131.371 132.449 1.00 55.08  ? 377 LEU A CA  1 
ATOM   1224 C C   . LEU A 1 377 ? 175.252 131.277 133.838 1.00 55.59  ? 377 LEU A C   1 
ATOM   1225 O O   . LEU A 1 377 ? 176.472 131.378 133.985 1.00 61.64  ? 377 LEU A O   1 
ATOM   1226 C CB  . LEU A 1 377 ? 174.126 132.783 132.187 1.00 52.64  ? 377 LEU A CB  1 
ATOM   1227 C CG  . LEU A 1 377 ? 175.217 133.834 132.043 1.00 54.07  ? 377 LEU A CG  1 
ATOM   1228 C CD1 . LEU A 1 377 ? 176.114 133.464 130.888 1.00 56.75  ? 377 LEU A CD1 1 
ATOM   1229 C CD2 . LEU A 1 377 ? 174.606 135.206 131.835 1.00 56.48  ? 377 LEU A CD2 1 
ATOM   1230 N N   . LEU A 1 378 ? 174.423 131.104 134.868 1.00 53.50  ? 378 LEU A N   1 
ATOM   1231 C CA  . LEU A 1 378 ? 174.932 130.984 136.228 1.00 54.83  ? 378 LEU A CA  1 
ATOM   1232 C C   . LEU A 1 378 ? 175.800 129.747 136.380 1.00 62.26  ? 378 LEU A C   1 
ATOM   1233 O O   . LEU A 1 378 ? 176.866 129.801 137.003 1.00 66.71  ? 378 LEU A O   1 
ATOM   1234 C CB  . LEU A 1 378 ? 173.774 130.936 137.222 1.00 53.26  ? 378 LEU A CB  1 
ATOM   1235 C CG  . LEU A 1 378 ? 173.246 132.251 137.790 1.00 51.54  ? 378 LEU A CG  1 
ATOM   1236 C CD1 . LEU A 1 378 ? 172.046 131.986 138.681 1.00 53.57  ? 378 LEU A CD1 1 
ATOM   1237 C CD2 . LEU A 1 378 ? 174.337 132.953 138.568 1.00 52.97  ? 378 LEU A CD2 1 
ATOM   1238 N N   . PHE A 1 379 ? 175.355 128.617 135.827 1.00 61.90  ? 379 PHE A N   1 
ATOM   1239 C CA  . PHE A 1 379 ? 176.175 127.413 135.878 1.00 61.47  ? 379 PHE A CA  1 
ATOM   1240 C C   . PHE A 1 379 ? 177.483 127.610 135.125 1.00 63.60  ? 379 PHE A C   1 
ATOM   1241 O O   . PHE A 1 379 ? 178.551 127.226 135.613 1.00 69.93  ? 379 PHE A O   1 
ATOM   1242 C CB  . PHE A 1 379 ? 175.400 126.226 135.312 1.00 61.83  ? 379 PHE A CB  1 
ATOM   1243 C CG  . PHE A 1 379 ? 176.273 125.104 134.836 1.00 62.80  ? 379 PHE A CG  1 
ATOM   1244 C CD1 . PHE A 1 379 ? 176.799 124.189 135.732 1.00 62.86  ? 379 PHE A CD1 1 
ATOM   1245 C CD2 . PHE A 1 379 ? 176.558 124.957 133.488 1.00 63.57  ? 379 PHE A CD2 1 
ATOM   1246 C CE1 . PHE A 1 379 ? 177.599 123.153 135.292 1.00 65.63  ? 379 PHE A CE1 1 
ATOM   1247 C CE2 . PHE A 1 379 ? 177.359 123.926 133.045 1.00 66.50  ? 379 PHE A CE2 1 
ATOM   1248 C CZ  . PHE A 1 379 ? 177.880 123.023 133.947 1.00 66.81  ? 379 PHE A CZ  1 
ATOM   1249 N N   . ARG A 1 380 ? 177.423 128.222 133.940 1.00 60.40  ? 380 ARG A N   1 
ATOM   1250 C CA  . ARG A 1 380 ? 178.632 128.408 133.146 1.00 61.91  ? 380 ARG A CA  1 
ATOM   1251 C C   . ARG A 1 380 ? 179.624 129.326 133.850 1.00 61.43  ? 380 ARG A C   1 
ATOM   1252 O O   . ARG A 1 380 ? 180.834 129.081 133.825 1.00 65.80  ? 380 ARG A O   1 
ATOM   1253 C CB  . ARG A 1 380 ? 178.264 128.954 131.769 1.00 60.07  ? 380 ARG A CB  1 
ATOM   1254 C CG  . ARG A 1 380 ? 179.441 129.177 130.850 1.00 59.52  ? 380 ARG A CG  1 
ATOM   1255 C CD  . ARG A 1 380 ? 178.985 129.211 129.407 1.00 58.22  ? 380 ARG A CD  1 
ATOM   1256 N NE  . ARG A 1 380 ? 177.876 130.136 129.218 1.00 61.65  ? 380 ARG A NE  1 
ATOM   1257 C CZ  . ARG A 1 380 ? 177.205 130.274 128.085 1.00 67.73  ? 380 ARG A CZ  1 
ATOM   1258 N NH1 . ARG A 1 380 ? 177.502 129.554 127.015 1.00 74.96  ? 380 ARG A NH1 1 
ATOM   1259 N NH2 . ARG A 1 380 ? 176.211 131.155 128.023 1.00 66.55  ? 380 ARG A NH2 1 
ATOM   1260 N N   . VAL A 1 381 ? 179.131 130.391 134.480 1.00 61.42  ? 381 VAL A N   1 
ATOM   1261 C CA  . VAL A 1 381 ? 180.012 131.324 135.172 1.00 61.15  ? 381 VAL A CA  1 
ATOM   1262 C C   . VAL A 1 381 ? 180.584 130.696 136.435 1.00 63.06  ? 381 VAL A C   1 
ATOM   1263 O O   . VAL A 1 381 ? 181.787 130.789 136.702 1.00 68.78  ? 381 VAL A O   1 
ATOM   1264 C CB  . VAL A 1 381 ? 179.254 132.627 135.484 1.00 57.44  ? 381 VAL A CB  1 
ATOM   1265 C CG1 . VAL A 1 381 ? 179.956 133.406 136.580 1.00 57.80  ? 381 VAL A CG1 1 
ATOM   1266 C CG2 . VAL A 1 381 ? 179.117 133.474 134.234 1.00 52.36  ? 381 VAL A CG2 1 
ATOM   1267 N N   . PHE A 1 382 ? 179.738 130.033 137.223 1.00 62.08  ? 382 PHE A N   1 
ATOM   1268 C CA  . PHE A 1 382 ? 180.112 129.695 138.591 1.00 68.51  ? 382 PHE A CA  1 
ATOM   1269 C C   . PHE A 1 382 ? 181.125 128.559 138.642 1.00 74.20  ? 382 PHE A C   1 
ATOM   1270 O O   . PHE A 1 382 ? 181.954 128.507 139.557 1.00 77.70  ? 382 PHE A O   1 
ATOM   1271 C CB  . PHE A 1 382 ? 178.864 129.333 139.393 1.00 73.64  ? 382 PHE A CB  1 
ATOM   1272 C CG  . PHE A 1 382 ? 178.886 129.835 140.806 1.00 73.49  ? 382 PHE A CG  1 
ATOM   1273 C CD1 . PHE A 1 382 ? 178.215 130.995 141.151 1.00 73.07  ? 382 PHE A CD1 1 
ATOM   1274 C CD2 . PHE A 1 382 ? 179.576 129.149 141.788 1.00 74.92  ? 382 PHE A CD2 1 
ATOM   1275 C CE1 . PHE A 1 382 ? 178.231 131.458 142.449 1.00 75.33  ? 382 PHE A CE1 1 
ATOM   1276 C CE2 . PHE A 1 382 ? 179.595 129.609 143.089 1.00 74.37  ? 382 PHE A CE2 1 
ATOM   1277 C CZ  . PHE A 1 382 ? 178.921 130.764 143.419 1.00 75.33  ? 382 PHE A CZ  1 
ATOM   1278 N N   . THR A 1 383 ? 181.062 127.628 137.691 1.00 73.04  ? 383 THR A N   1 
ATOM   1279 C CA  . THR A 1 383 ? 181.873 126.421 137.786 1.00 75.82  ? 383 THR A CA  1 
ATOM   1280 C C   . THR A 1 383 ? 183.370 126.690 137.713 1.00 82.90  ? 383 THR A C   1 
ATOM   1281 O O   . THR A 1 383 ? 184.069 126.605 138.729 1.00 88.10  ? 383 THR A O   1 
ATOM   1282 C CB  . THR A 1 383 ? 181.494 125.436 136.682 1.00 71.27  ? 383 THR A CB  1 
ATOM   1283 O OG1 . THR A 1 383 ? 181.462 126.116 135.421 1.00 62.59  ? 383 THR A OG1 1 
ATOM   1284 C CG2 . THR A 1 383 ? 180.141 124.819 136.970 1.00 74.46  ? 383 THR A CG2 1 
ATOM   1285 N N   . ALA A 1 384 ? 183.861 127.049 136.528 1.00 83.61  ? 384 ALA A N   1 
ATOM   1286 C CA  . ALA A 1 384 ? 185.294 127.022 136.259 1.00 84.29  ? 384 ALA A CA  1 
ATOM   1287 C C   . ALA A 1 384 ? 185.568 127.548 134.855 1.00 81.10  ? 384 ALA A C   1 
ATOM   1288 O O   . ALA A 1 384 ? 184.624 127.769 134.088 1.00 80.88  ? 384 ALA A O   1 
ATOM   1289 C CB  . ALA A 1 384 ? 185.832 125.597 136.423 1.00 85.62  ? 384 ALA A CB  1 
ATOM   1290 N N   . PRO A 1 385 ? 186.842 127.775 134.474 1.00 75.72  ? 385 PRO A N   1 
ATOM   1291 C CA  . PRO A 1 385 ? 187.164 128.160 133.094 1.00 78.16  ? 385 PRO A CA  1 
ATOM   1292 C C   . PRO A 1 385 ? 187.103 127.001 132.101 1.00 77.62  ? 385 PRO A C   1 
ATOM   1293 O O   . PRO A 1 385 ? 187.989 126.828 131.262 1.00 73.24  ? 385 PRO A O   1 
ATOM   1294 C CB  . PRO A 1 385 ? 188.590 128.709 133.226 1.00 75.98  ? 385 PRO A CB  1 
ATOM   1295 C CG  . PRO A 1 385 ? 189.156 127.966 134.367 1.00 72.39  ? 385 PRO A CG  1 
ATOM   1296 C CD  . PRO A 1 385 ? 188.030 127.843 135.342 1.00 68.40  ? 385 PRO A CD  1 
ATOM   1297 N N   . PHE A 1 386 ? 186.039 126.205 132.191 1.00 75.50  ? 386 PHE A N   1 
ATOM   1298 C CA  . PHE A 1 386 ? 185.862 125.032 131.348 1.00 73.04  ? 386 PHE A CA  1 
ATOM   1299 C C   . PHE A 1 386 ? 185.018 125.311 130.111 1.00 75.76  ? 386 PHE A C   1 
ATOM   1300 O O   . PHE A 1 386 ? 184.801 124.400 129.307 1.00 78.03  ? 386 PHE A O   1 
ATOM   1301 C CB  . PHE A 1 386 ? 185.235 123.896 132.155 1.00 72.83  ? 386 PHE A CB  1 
ATOM   1302 C CG  . PHE A 1 386 ? 186.104 123.389 133.268 1.00 77.15  ? 386 PHE A CG  1 
ATOM   1303 C CD1 . PHE A 1 386 ? 187.479 123.510 133.203 1.00 82.69  ? 386 PHE A CD1 1 
ATOM   1304 C CD2 . PHE A 1 386 ? 185.544 122.785 134.379 1.00 74.97  ? 386 PHE A CD2 1 
ATOM   1305 C CE1 . PHE A 1 386 ? 188.280 123.042 134.226 1.00 83.09  ? 386 PHE A CE1 1 
ATOM   1306 C CE2 . PHE A 1 386 ? 186.340 122.315 135.404 1.00 76.73  ? 386 PHE A CE2 1 
ATOM   1307 C CZ  . PHE A 1 386 ? 187.709 122.445 135.328 1.00 81.91  ? 386 PHE A CZ  1 
ATOM   1308 N N   . HIS A 1 387 ? 184.544 126.542 129.936 1.00 77.14  ? 387 HIS A N   1 
ATOM   1309 C CA  . HIS A 1 387 ? 183.696 126.907 128.811 1.00 73.12  ? 387 HIS A CA  1 
ATOM   1310 C C   . HIS A 1 387 ? 184.285 128.115 128.099 1.00 73.88  ? 387 HIS A C   1 
ATOM   1311 O O   . HIS A 1 387 ? 184.919 128.968 128.727 1.00 74.23  ? 387 HIS A O   1 
ATOM   1312 C CB  . HIS A 1 387 ? 182.268 127.229 129.267 1.00 70.98  ? 387 HIS A CB  1 
ATOM   1313 C CG  . HIS A 1 387 ? 181.818 126.448 130.463 1.00 69.08  ? 387 HIS A CG  1 
ATOM   1314 N ND1 . HIS A 1 387 ? 180.902 125.421 130.381 1.00 66.99  ? 387 HIS A ND1 1 
ATOM   1315 C CD2 . HIS A 1 387 ? 182.142 126.556 131.774 1.00 68.26  ? 387 HIS A CD2 1 
ATOM   1316 C CE1 . HIS A 1 387 ? 180.689 124.926 131.587 1.00 68.72  ? 387 HIS A CE1 1 
ATOM   1317 N NE2 . HIS A 1 387 ? 181.430 125.596 132.450 1.00 67.17  ? 387 HIS A NE2 1 
ATOM   1318 N N   . LYS A 1 388 ? 184.077 128.185 126.786 1.00 74.26  ? 388 LYS A N   1 
ATOM   1319 C CA  . LYS A 1 388 ? 184.506 129.351 126.026 1.00 74.31  ? 388 LYS A CA  1 
ATOM   1320 C C   . LYS A 1 388 ? 183.746 130.582 126.498 1.00 73.02  ? 388 LYS A C   1 
ATOM   1321 O O   . LYS A 1 388 ? 182.528 130.537 126.690 1.00 76.20  ? 388 LYS A O   1 
ATOM   1322 C CB  . LYS A 1 388 ? 184.279 129.123 124.533 1.00 75.17  ? 388 LYS A CB  1 
ATOM   1323 C CG  . LYS A 1 388 ? 184.707 130.282 123.653 1.00 73.45  ? 388 LYS A CG  1 
ATOM   1324 C CD  . LYS A 1 388 ? 184.466 129.969 122.188 1.00 77.91  ? 388 LYS A CD  1 
ATOM   1325 C CE  . LYS A 1 388 ? 184.893 131.123 121.298 1.00 87.98  ? 388 LYS A CE  1 
ATOM   1326 N NZ  . LYS A 1 388 ? 184.700 130.809 119.854 1.00 102.11 ? 388 LYS A NZ  1 
ATOM   1327 N N   . VAL A 1 389 ? 184.463 131.685 126.678 1.00 67.58  ? 389 VAL A N   1 
ATOM   1328 C CA  . VAL A 1 389 ? 183.912 132.865 127.333 1.00 66.22  ? 389 VAL A CA  1 
ATOM   1329 C C   . VAL A 1 389 ? 183.259 133.771 126.296 1.00 66.67  ? 389 VAL A C   1 
ATOM   1330 O O   . VAL A 1 389 ? 183.941 134.348 125.442 1.00 65.20  ? 389 VAL A O   1 
ATOM   1331 C CB  . VAL A 1 389 ? 184.998 133.618 128.114 1.00 61.92  ? 389 VAL A CB  1 
ATOM   1332 C CG1 . VAL A 1 389 ? 184.389 134.779 128.875 1.00 57.49  ? 389 VAL A CG1 1 
ATOM   1333 C CG2 . VAL A 1 389 ? 185.711 132.673 129.060 1.00 66.32  ? 389 VAL A CG2 1 
ATOM   1334 N N   . GLY A 1 390 ? 181.933 133.899 126.378 1.00 65.46  ? 390 GLY A N   1 
ATOM   1335 C CA  . GLY A 1 390 ? 181.200 134.887 125.621 1.00 60.53  ? 390 GLY A CA  1 
ATOM   1336 C C   . GLY A 1 390 ? 180.922 136.128 126.458 1.00 59.41  ? 390 GLY A C   1 
ATOM   1337 O O   . GLY A 1 390 ? 181.358 136.258 127.598 1.00 62.62  ? 390 GLY A O   1 
ATOM   1338 N N   . PHE A 1 391 ? 180.172 137.056 125.861 1.00 58.82  ? 391 PHE A N   1 
ATOM   1339 C CA  . PHE A 1 391 ? 179.930 138.329 126.534 1.00 56.55  ? 391 PHE A CA  1 
ATOM   1340 C C   . PHE A 1 391 ? 179.093 138.146 127.793 1.00 54.94  ? 391 PHE A C   1 
ATOM   1341 O O   . PHE A 1 391 ? 179.361 138.784 128.819 1.00 58.90  ? 391 PHE A O   1 
ATOM   1342 C CB  . PHE A 1 391 ? 179.253 139.318 125.590 1.00 54.16  ? 391 PHE A CB  1 
ATOM   1343 C CG  . PHE A 1 391 ? 179.206 140.720 126.126 1.00 57.41  ? 391 PHE A CG  1 
ATOM   1344 C CD1 . PHE A 1 391 ? 180.224 141.613 125.851 1.00 60.99  ? 391 PHE A CD1 1 
ATOM   1345 C CD2 . PHE A 1 391 ? 178.153 141.140 126.916 1.00 55.60  ? 391 PHE A CD2 1 
ATOM   1346 C CE1 . PHE A 1 391 ? 180.187 142.901 126.348 1.00 56.44  ? 391 PHE A CE1 1 
ATOM   1347 C CE2 . PHE A 1 391 ? 178.113 142.425 127.416 1.00 49.28  ? 391 PHE A CE2 1 
ATOM   1348 C CZ  . PHE A 1 391 ? 179.130 143.305 127.131 1.00 52.03  ? 391 PHE A CZ  1 
ATOM   1349 N N   . ALA A 1 392 ? 178.071 137.291 127.734 1.00 48.00  ? 392 ALA A N   1 
ATOM   1350 C CA  . ALA A 1 392 ? 177.177 137.131 128.876 1.00 47.84  ? 392 ALA A CA  1 
ATOM   1351 C C   . ALA A 1 392 ? 177.921 136.603 130.095 1.00 51.55  ? 392 ALA A C   1 
ATOM   1352 O O   . ALA A 1 392 ? 177.676 137.051 131.221 1.00 50.58  ? 392 ALA A O   1 
ATOM   1353 C CB  . ALA A 1 392 ? 176.019 136.208 128.504 1.00 46.61  ? 392 ALA A CB  1 
ATOM   1354 N N   . ASP A 1 393 ? 178.835 135.652 129.889 1.00 54.35  ? 393 ASP A N   1 
ATOM   1355 C CA  . ASP A 1 393 ? 179.597 135.092 131.000 1.00 53.09  ? 393 ASP A CA  1 
ATOM   1356 C C   . ASP A 1 393 ? 180.398 136.173 131.712 1.00 57.15  ? 393 ASP A C   1 
ATOM   1357 O O   . ASP A 1 393 ? 180.312 136.323 132.936 1.00 60.80  ? 393 ASP A O   1 
ATOM   1358 C CB  . ASP A 1 393 ? 180.530 133.995 130.491 1.00 52.30  ? 393 ASP A CB  1 
ATOM   1359 C CG  . ASP A 1 393 ? 179.955 133.237 129.316 1.00 60.27  ? 393 ASP A CG  1 
ATOM   1360 O OD1 . ASP A 1 393 ? 178.838 132.698 129.436 1.00 67.90  ? 393 ASP A OD1 1 
ATOM   1361 O OD2 . ASP A 1 393 ? 180.621 133.188 128.263 1.00 60.31  ? 393 ASP A OD2 1 
ATOM   1362 N N   . PHE A 1 394 ? 181.178 136.944 130.953 1.00 53.54  ? 394 PHE A N   1 
ATOM   1363 C CA  . PHE A 1 394 ? 182.008 137.986 131.545 1.00 52.35  ? 394 PHE A CA  1 
ATOM   1364 C C   . PHE A 1 394 ? 181.151 139.043 132.227 1.00 52.01  ? 394 PHE A C   1 
ATOM   1365 O O   . PHE A 1 394 ? 181.464 139.501 133.333 1.00 53.12  ? 394 PHE A O   1 
ATOM   1366 C CB  . PHE A 1 394 ? 182.898 138.611 130.469 1.00 51.55  ? 394 PHE A CB  1 
ATOM   1367 C CG  . PHE A 1 394 ? 182.938 140.111 130.503 1.00 48.85  ? 394 PHE A CG  1 
ATOM   1368 C CD1 . PHE A 1 394 ? 183.753 140.780 131.393 1.00 50.47  ? 394 PHE A CD1 1 
ATOM   1369 C CD2 . PHE A 1 394 ? 182.169 140.854 129.627 1.00 53.21  ? 394 PHE A CD2 1 
ATOM   1370 C CE1 . PHE A 1 394 ? 183.794 142.154 131.417 1.00 52.44  ? 394 PHE A CE1 1 
ATOM   1371 C CE2 . PHE A 1 394 ? 182.207 142.230 129.651 1.00 56.89  ? 394 PHE A CE2 1 
ATOM   1372 C CZ  . PHE A 1 394 ? 183.020 142.878 130.547 1.00 54.53  ? 394 PHE A CZ  1 
ATOM   1373 N N   . TRP A 1 395 ? 180.054 139.438 131.580 1.00 50.42  ? 395 TRP A N   1 
ATOM   1374 C CA  . TRP A 1 395 ? 179.221 140.497 132.131 1.00 48.77  ? 395 TRP A CA  1 
ATOM   1375 C C   . TRP A 1 395 ? 178.580 140.069 133.445 1.00 51.67  ? 395 TRP A C   1 
ATOM   1376 O O   . TRP A 1 395 ? 178.611 140.812 134.430 1.00 55.31  ? 395 TRP A O   1 
ATOM   1377 C CB  . TRP A 1 395 ? 178.164 140.917 131.114 1.00 42.90  ? 395 TRP A CB  1 
ATOM   1378 C CG  . TRP A 1 395 ? 177.322 142.043 131.593 1.00 44.84  ? 395 TRP A CG  1 
ATOM   1379 C CD1 . TRP A 1 395 ? 177.632 143.369 131.564 1.00 43.56  ? 395 TRP A CD1 1 
ATOM   1380 C CD2 . TRP A 1 395 ? 176.025 141.946 132.183 1.00 43.50  ? 395 TRP A CD2 1 
ATOM   1381 N NE1 . TRP A 1 395 ? 176.606 144.105 132.099 1.00 41.86  ? 395 TRP A NE1 1 
ATOM   1382 C CE2 . TRP A 1 395 ? 175.606 143.253 132.486 1.00 42.21  ? 395 TRP A CE2 1 
ATOM   1383 C CE3 . TRP A 1 395 ? 175.175 140.880 132.482 1.00 44.70  ? 395 TRP A CE3 1 
ATOM   1384 C CZ2 . TRP A 1 395 ? 174.379 143.520 133.072 1.00 41.76  ? 395 TRP A CZ2 1 
ATOM   1385 C CZ3 . TRP A 1 395 ? 173.962 141.147 133.065 1.00 43.31  ? 395 TRP A CZ3 1 
ATOM   1386 C CH2 . TRP A 1 395 ? 173.573 142.455 133.354 1.00 43.07  ? 395 TRP A CH2 1 
ATOM   1387 N N   . LEU A 1 396 ? 178.005 138.863 133.488 1.00 50.84  ? 396 LEU A N   1 
ATOM   1388 C CA  . LEU A 1 396 ? 177.399 138.397 134.733 1.00 49.23  ? 396 LEU A CA  1 
ATOM   1389 C C   . LEU A 1 396 ? 178.454 138.167 135.803 1.00 51.28  ? 396 LEU A C   1 
ATOM   1390 O O   . LEU A 1 396 ? 178.194 138.379 136.993 1.00 53.80  ? 396 LEU A O   1 
ATOM   1391 C CB  . LEU A 1 396 ? 176.592 137.122 134.496 1.00 48.02  ? 396 LEU A CB  1 
ATOM   1392 C CG  . LEU A 1 396 ? 176.005 136.479 135.756 1.00 49.53  ? 396 LEU A CG  1 
ATOM   1393 C CD1 . LEU A 1 396 ? 175.144 137.467 136.521 1.00 51.85  ? 396 LEU A CD1 1 
ATOM   1394 C CD2 . LEU A 1 396 ? 175.210 135.236 135.416 1.00 49.53  ? 396 LEU A CD2 1 
ATOM   1395 N N   . ALA A 1 397 ? 179.653 137.743 135.405 1.00 51.41  ? 397 ALA A N   1 
ATOM   1396 C CA  . ALA A 1 397 ? 180.734 137.613 136.370 1.00 50.62  ? 397 ALA A CA  1 
ATOM   1397 C C   . ALA A 1 397 ? 181.044 138.958 137.007 1.00 56.57  ? 397 ALA A C   1 
ATOM   1398 O O   . ALA A 1 397 ? 181.224 139.055 138.224 1.00 60.09  ? 397 ALA A O   1 
ATOM   1399 C CB  . ALA A 1 397 ? 181.971 137.032 135.690 1.00 48.35  ? 397 ALA A CB  1 
ATOM   1400 N N   . ASP A 1 398 ? 181.084 140.017 136.198 1.00 51.76  ? 398 ASP A N   1 
ATOM   1401 C CA  . ASP A 1 398 ? 181.317 141.350 136.747 1.00 49.64  ? 398 ASP A CA  1 
ATOM   1402 C C   . ASP A 1 398 ? 180.166 141.794 137.643 1.00 54.96  ? 398 ASP A C   1 
ATOM   1403 O O   . ASP A 1 398 ? 180.385 142.405 138.696 1.00 61.89  ? 398 ASP A O   1 
ATOM   1404 C CB  . ASP A 1 398 ? 181.540 142.352 135.620 1.00 52.07  ? 398 ASP A CB  1 
ATOM   1405 C CG  . ASP A 1 398 ? 183.004 142.630 135.378 1.00 57.30  ? 398 ASP A CG  1 
ATOM   1406 O OD1 . ASP A 1 398 ? 183.814 142.360 136.286 1.00 60.56  ? 398 ASP A OD1 1 
ATOM   1407 O OD2 . ASP A 1 398 ? 183.348 143.125 134.287 1.00 57.86  ? 398 ASP A OD2 1 
ATOM   1408 N N   . GLN A 1 399 ? 178.930 141.508 137.238 1.00 50.47  ? 399 GLN A N   1 
ATOM   1409 C CA  . GLN A 1 399 ? 177.777 141.893 138.045 1.00 51.31  ? 399 GLN A CA  1 
ATOM   1410 C C   . GLN A 1 399 ? 177.864 141.241 139.419 1.00 57.17  ? 399 GLN A C   1 
ATOM   1411 O O   . GLN A 1 399 ? 177.597 141.885 140.436 1.00 54.62  ? 399 GLN A O   1 
ATOM   1412 C CB  . GLN A 1 399 ? 176.464 141.501 137.369 1.00 52.99  ? 399 GLN A CB  1 
ATOM   1413 C CG  . GLN A 1 399 ? 176.304 141.975 135.944 1.00 48.96  ? 399 GLN A CG  1 
ATOM   1414 C CD  . GLN A 1 399 ? 176.409 143.466 135.808 1.00 46.34  ? 399 GLN A CD  1 
ATOM   1415 O OE1 . GLN A 1 399 ? 177.139 143.968 134.960 1.00 50.60  ? 399 GLN A OE1 1 
ATOM   1416 N NE2 . GLN A 1 399 ? 175.670 144.189 136.632 1.00 45.73  ? 399 GLN A NE2 1 
ATOM   1417 N N   . LEU A 1 400 ? 178.232 139.960 139.453 1.00 65.10  ? 400 LEU A N   1 
ATOM   1418 C CA  . LEU A 1 400 ? 178.481 139.288 140.722 1.00 57.76  ? 400 LEU A CA  1 
ATOM   1419 C C   . LEU A 1 400 ? 179.677 139.877 141.448 1.00 58.24  ? 400 LEU A C   1 
ATOM   1420 O O   . LEU A 1 400 ? 179.714 139.848 142.681 1.00 63.35  ? 400 LEU A O   1 
ATOM   1421 C CB  . LEU A 1 400 ? 178.707 137.791 140.504 1.00 55.66  ? 400 LEU A CB  1 
ATOM   1422 C CG  . LEU A 1 400 ? 177.599 136.978 139.832 1.00 59.74  ? 400 LEU A CG  1 
ATOM   1423 C CD1 . LEU A 1 400 ? 178.039 135.537 139.657 1.00 63.24  ? 400 LEU A CD1 1 
ATOM   1424 C CD2 . LEU A 1 400 ? 176.318 137.052 140.631 1.00 59.25  ? 400 LEU A CD2 1 
ATOM   1425 N N   . ASN A 1 401 ? 180.660 140.390 140.707 1.00 58.38  ? 401 ASN A N   1 
ATOM   1426 C CA  . ASN A 1 401 ? 181.807 141.038 141.331 1.00 63.01  ? 401 ASN A CA  1 
ATOM   1427 C C   . ASN A 1 401 ? 181.377 142.275 142.106 1.00 62.37  ? 401 ASN A C   1 
ATOM   1428 O O   . ASN A 1 401 ? 181.918 142.562 143.179 1.00 64.25  ? 401 ASN A O   1 
ATOM   1429 C CB  . ASN A 1 401 ? 182.845 141.397 140.267 1.00 62.80  ? 401 ASN A CB  1 
ATOM   1430 C CG  . ASN A 1 401 ? 184.241 141.529 140.831 1.00 69.50  ? 401 ASN A CG  1 
ATOM   1431 O OD1 . ASN A 1 401 ? 185.166 140.857 140.381 1.00 65.44  ? 401 ASN A OD1 1 
ATOM   1432 N ND2 . ASN A 1 401 ? 184.405 142.398 141.819 1.00 72.10  ? 401 ASN A ND2 1 
ATOM   1433 N N   . SER A 1 402 ? 180.407 143.013 141.581 1.00 60.54  ? 402 SER A N   1 
ATOM   1434 C CA  . SER A 1 402 ? 179.881 144.193 142.255 1.00 61.57  ? 402 SER A CA  1 
ATOM   1435 C C   . SER A 1 402 ? 178.738 143.879 143.211 1.00 63.94  ? 402 SER A C   1 
ATOM   1436 O O   . SER A 1 402 ? 178.153 144.806 143.776 1.00 67.20  ? 402 SER A O   1 
ATOM   1437 C CB  . SER A 1 402 ? 179.413 145.223 141.228 1.00 58.02  ? 402 SER A CB  1 
ATOM   1438 O OG  . SER A 1 402 ? 180.505 145.722 140.477 1.00 63.97  ? 402 SER A OG  1 
ATOM   1439 N N   . LEU A 1 403 ? 178.403 142.608 143.400 1.00 66.39  ? 403 LEU A N   1 
ATOM   1440 C CA  . LEU A 1 403 ? 177.278 142.190 144.227 1.00 61.71  ? 403 LEU A CA  1 
ATOM   1441 C C   . LEU A 1 403 ? 177.705 141.117 145.222 1.00 60.98  ? 403 LEU A C   1 
ATOM   1442 O O   . LEU A 1 403 ? 176.968 140.172 145.501 1.00 63.66  ? 403 LEU A O   1 
ATOM   1443 C CB  . LEU A 1 403 ? 176.130 141.694 143.350 1.00 62.15  ? 403 LEU A CB  1 
ATOM   1444 C CG  . LEU A 1 403 ? 174.708 141.670 143.903 1.00 62.52  ? 403 LEU A CG  1 
ATOM   1445 C CD1 . LEU A 1 403 ? 174.343 143.023 144.462 1.00 62.40  ? 403 LEU A CD1 1 
ATOM   1446 C CD2 . LEU A 1 403 ? 173.741 141.276 142.809 1.00 59.01  ? 403 LEU A CD2 1 
ATOM   1447 N N   . SER A 1 404 ? 178.915 141.248 145.767 1.00 63.71  ? 404 SER A N   1 
ATOM   1448 C CA  . SER A 1 404 ? 179.440 140.243 146.684 1.00 68.11  ? 404 SER A CA  1 
ATOM   1449 C C   . SER A 1 404 ? 178.718 140.228 148.023 1.00 64.15  ? 404 SER A C   1 
ATOM   1450 O O   . SER A 1 404 ? 178.873 139.263 148.784 1.00 63.59  ? 404 SER A O   1 
ATOM   1451 C CB  . SER A 1 404 ? 180.934 140.471 146.909 1.00 66.88  ? 404 SER A CB  1 
ATOM   1452 O OG  . SER A 1 404 ? 181.169 141.730 147.511 1.00 69.95  ? 404 SER A OG  1 
ATOM   1453 N N   . VAL A 1 405 ? 177.939 141.267 148.329 1.00 61.28  ? 405 VAL A N   1 
ATOM   1454 C CA  . VAL A 1 405 ? 177.202 141.285 149.585 1.00 64.98  ? 405 VAL A CA  1 
ATOM   1455 C C   . VAL A 1 405 ? 176.187 140.156 149.620 1.00 67.12  ? 405 VAL A C   1 
ATOM   1456 O O   . VAL A 1 405 ? 175.843 139.659 150.694 1.00 76.64  ? 405 VAL A O   1 
ATOM   1457 C CB  . VAL A 1 405 ? 176.533 142.654 149.802 1.00 71.89  ? 405 VAL A CB  1 
ATOM   1458 C CG1 . VAL A 1 405 ? 176.044 142.779 151.229 1.00 67.31  ? 405 VAL A CG1 1 
ATOM   1459 C CG2 . VAL A 1 405 ? 177.499 143.771 149.476 1.00 74.74  ? 405 VAL A CG2 1 
ATOM   1460 N N   . ILE A 1 406 ? 175.707 139.717 148.458 1.00 63.04  ? 406 ILE A N   1 
ATOM   1461 C CA  . ILE A 1 406 ? 174.806 138.571 148.425 1.00 63.51  ? 406 ILE A CA  1 
ATOM   1462 C C   . ILE A 1 406 ? 175.502 137.327 148.961 1.00 67.46  ? 406 ILE A C   1 
ATOM   1463 O O   . ILE A 1 406 ? 174.963 136.621 149.822 1.00 69.48  ? 406 ILE A O   1 
ATOM   1464 C CB  . ILE A 1 406 ? 174.274 138.355 146.999 1.00 60.93  ? 406 ILE A CB  1 
ATOM   1465 C CG1 . ILE A 1 406 ? 173.197 139.388 146.678 1.00 58.81  ? 406 ILE A CG1 1 
ATOM   1466 C CG2 . ILE A 1 406 ? 173.744 136.946 146.832 1.00 64.40  ? 406 ILE A CG2 1 
ATOM   1467 C CD1 . ILE A 1 406 ? 172.468 139.118 145.390 1.00 57.33  ? 406 ILE A CD1 1 
ATOM   1468 N N   . LEU A 1 407 ? 176.714 137.045 148.476 1.00 65.33  ? 407 LEU A N   1 
ATOM   1469 C CA  . LEU A 1 407 ? 177.444 135.871 148.946 1.00 67.36  ? 407 LEU A CA  1 
ATOM   1470 C C   . LEU A 1 407 ? 177.814 136.008 150.415 1.00 73.37  ? 407 LEU A C   1 
ATOM   1471 O O   . LEU A 1 407 ? 177.720 135.045 151.190 1.00 83.19  ? 407 LEU A O   1 
ATOM   1472 C CB  . LEU A 1 407 ? 178.696 135.649 148.098 1.00 63.95  ? 407 LEU A CB  1 
ATOM   1473 C CG  . LEU A 1 407 ? 178.529 134.857 146.801 1.00 64.18  ? 407 LEU A CG  1 
ATOM   1474 C CD1 . LEU A 1 407 ? 177.864 135.693 145.723 1.00 60.58  ? 407 LEU A CD1 1 
ATOM   1475 C CD2 . LEU A 1 407 ? 179.870 134.335 146.326 1.00 66.49  ? 407 LEU A CD2 1 
ATOM   1476 N N   . MET A 1 408 ? 178.247 137.203 150.818 1.00 72.11  ? 408 MET A N   1 
ATOM   1477 C CA  . MET A 1 408 ? 178.596 137.405 152.218 1.00 76.53  ? 408 MET A CA  1 
ATOM   1478 C C   . MET A 1 408 ? 177.389 137.222 153.125 1.00 79.76  ? 408 MET A C   1 
ATOM   1479 O O   . MET A 1 408 ? 177.514 136.653 154.212 1.00 83.76  ? 408 MET A O   1 
ATOM   1480 C CB  . MET A 1 408 ? 179.218 138.784 152.416 1.00 78.67  ? 408 MET A CB  1 
ATOM   1481 C CG  . MET A 1 408 ? 180.569 138.939 151.746 1.00 85.49  ? 408 MET A CG  1 
ATOM   1482 S SD  . MET A 1 408 ? 181.771 137.735 152.338 1.00 101.45 ? 408 MET A SD  1 
ATOM   1483 C CE  . MET A 1 408 ? 181.808 138.133 154.083 1.00 96.85  ? 408 MET A CE  1 
ATOM   1484 N N   . ASP A 1 409 ? 176.214 137.687 152.701 1.00 74.99  ? 409 ASP A N   1 
ATOM   1485 C CA  . ASP A 1 409 ? 175.013 137.492 153.501 1.00 73.97  ? 409 ASP A CA  1 
ATOM   1486 C C   . ASP A 1 409 ? 174.585 136.033 153.511 1.00 82.35  ? 409 ASP A C   1 
ATOM   1487 O O   . ASP A 1 409 ? 174.041 135.554 154.508 1.00 88.65  ? 409 ASP A O   1 
ATOM   1488 C CB  . ASP A 1 409 ? 173.887 138.383 152.986 1.00 75.35  ? 409 ASP A CB  1 
ATOM   1489 C CG  . ASP A 1 409 ? 174.071 139.831 153.380 1.00 78.70  ? 409 ASP A CG  1 
ATOM   1490 O OD1 . ASP A 1 409 ? 175.059 140.137 154.078 1.00 75.97  ? 409 ASP A OD1 1 
ATOM   1491 O OD2 . ASP A 1 409 ? 173.221 140.662 153.002 1.00 78.92  ? 409 ASP A OD2 1 
ATOM   1492 N N   . LEU A 1 410 ? 174.810 135.310 152.412 1.00 83.96  ? 410 LEU A N   1 
ATOM   1493 C CA  . LEU A 1 410 ? 174.560 133.872 152.431 1.00 85.92  ? 410 LEU A CA  1 
ATOM   1494 C C   . LEU A 1 410 ? 175.411 133.190 153.492 1.00 89.53  ? 410 LEU A C   1 
ATOM   1495 O O   . LEU A 1 410 ? 174.905 132.393 154.295 1.00 92.65  ? 410 LEU A O   1 
ATOM   1496 C CB  . LEU A 1 410 ? 174.843 133.268 151.055 1.00 80.41  ? 410 LEU A CB  1 
ATOM   1497 C CG  . LEU A 1 410 ? 173.796 133.479 149.964 1.00 79.50  ? 410 LEU A CG  1 
ATOM   1498 C CD1 . LEU A 1 410 ? 174.302 132.967 148.625 1.00 70.93  ? 410 LEU A CD1 1 
ATOM   1499 C CD2 . LEU A 1 410 ? 172.507 132.782 150.349 1.00 85.71  ? 410 LEU A CD2 1 
ATOM   1500 N N   . GLU A 1 411 ? 176.705 133.511 153.522 1.00 90.72  ? 411 GLU A N   1 
ATOM   1501 C CA  . GLU A 1 411 ? 177.586 132.928 154.530 1.00 94.58  ? 411 GLU A CA  1 
ATOM   1502 C C   . GLU A 1 411 ? 177.178 133.355 155.935 1.00 96.62  ? 411 GLU A C   1 
ATOM   1503 O O   . GLU A 1 411 ? 177.225 132.552 156.874 1.00 100.09 ? 411 GLU A O   1 
ATOM   1504 C CB  . GLU A 1 411 ? 179.037 133.312 154.250 1.00 90.31  ? 411 GLU A CB  1 
ATOM   1505 C CG  . GLU A 1 411 ? 179.576 132.739 152.957 1.00 91.86  ? 411 GLU A CG  1 
ATOM   1506 C CD  . GLU A 1 411 ? 179.459 131.231 152.900 1.00 96.88  ? 411 GLU A CD  1 
ATOM   1507 O OE1 . GLU A 1 411 ? 179.732 130.573 153.925 1.00 99.96  ? 411 GLU A OE1 1 
ATOM   1508 O OE2 . GLU A 1 411 ? 179.088 130.703 151.832 1.00 95.06  ? 411 GLU A OE2 1 
ATOM   1509 N N   . TYR A 1 412 ? 176.782 134.619 156.102 1.00 94.77  ? 412 TYR A N   1 
ATOM   1510 C CA  . TYR A 1 412 ? 176.365 135.093 157.417 1.00 100.01 ? 412 TYR A CA  1 
ATOM   1511 C C   . TYR A 1 412 ? 175.103 134.386 157.888 1.00 102.28 ? 412 TYR A C   1 
ATOM   1512 O O   . TYR A 1 412 ? 174.983 134.043 159.066 1.00 105.71 ? 412 TYR A O   1 
ATOM   1513 C CB  . TYR A 1 412 ? 176.149 136.604 157.398 1.00 97.66  ? 412 TYR A CB  1 
ATOM   1514 C CG  . TYR A 1 412 ? 175.724 137.152 158.739 1.00 95.62  ? 412 TYR A CG  1 
ATOM   1515 C CD1 . TYR A 1 412 ? 176.655 137.375 159.743 1.00 99.76  ? 412 TYR A CD1 1 
ATOM   1516 C CD2 . TYR A 1 412 ? 174.394 137.436 159.005 1.00 94.17  ? 412 TYR A CD2 1 
ATOM   1517 C CE1 . TYR A 1 412 ? 176.275 137.871 160.974 1.00 100.37 ? 412 TYR A CE1 1 
ATOM   1518 C CE2 . TYR A 1 412 ? 174.003 137.932 160.233 1.00 99.04  ? 412 TYR A CE2 1 
ATOM   1519 C CZ  . TYR A 1 412 ? 174.948 138.148 161.213 1.00 100.60 ? 412 TYR A CZ  1 
ATOM   1520 O OH  . TYR A 1 412 ? 174.566 138.642 162.438 1.00 102.91 ? 412 TYR A OH  1 
ATOM   1521 N N   . MET A 1 413 ? 174.142 134.173 156.987 1.00 99.76  ? 413 MET A N   1 
ATOM   1522 C CA  . MET A 1 413 ? 172.932 133.444 157.348 1.00 99.73  ? 413 MET A CA  1 
ATOM   1523 C C   . MET A 1 413 ? 173.250 132.002 157.712 1.00 106.19 ? 413 MET A C   1 
ATOM   1524 O O   . MET A 1 413 ? 172.673 131.448 158.656 1.00 111.77 ? 413 MET A O   1 
ATOM   1525 C CB  . MET A 1 413 ? 171.925 133.492 156.200 1.00 94.19  ? 413 MET A CB  1 
ATOM   1526 C CG  . MET A 1 413 ? 171.259 134.836 156.002 1.00 91.54  ? 413 MET A CG  1 
ATOM   1527 S SD  . MET A 1 413 ? 170.178 134.841 154.561 1.00 99.79  ? 413 MET A SD  1 
ATOM   1528 C CE  . MET A 1 413 ? 169.087 133.472 154.945 1.00 95.00  ? 413 MET A CE  1 
ATOM   1529 N N   . ILE A 1 414 ? 174.164 131.375 156.970 1.00 102.04 ? 414 ILE A N   1 
ATOM   1530 C CA  . ILE A 1 414 ? 174.556 130.006 157.289 1.00 101.96 ? 414 ILE A CA  1 
ATOM   1531 C C   . ILE A 1 414 ? 175.195 129.949 158.671 1.00 109.46 ? 414 ILE A C   1 
ATOM   1532 O O   . ILE A 1 414 ? 174.880 129.073 159.485 1.00 113.59 ? 414 ILE A O   1 
ATOM   1533 C CB  . ILE A 1 414 ? 175.493 129.451 156.203 1.00 102.56 ? 414 ILE A CB  1 
ATOM   1534 C CG1 . ILE A 1 414 ? 174.711 129.222 154.909 1.00 96.68  ? 414 ILE A CG1 1 
ATOM   1535 C CG2 . ILE A 1 414 ? 176.157 128.169 156.675 1.00 111.75 ? 414 ILE A CG2 1 
ATOM   1536 C CD1 . ILE A 1 414 ? 175.525 128.596 153.806 1.00 94.22  ? 414 ILE A CD1 1 
ATOM   1537 N N   . CYS A 1 415 ? 176.090 130.895 158.965 1.00 108.98 ? 415 CYS A N   1 
ATOM   1538 C CA  . CYS A 1 415 ? 176.715 130.939 160.284 1.00 114.99 ? 415 CYS A CA  1 
ATOM   1539 C C   . CYS A 1 415 ? 175.697 131.227 161.382 1.00 117.47 ? 415 CYS A C   1 
ATOM   1540 O O   . CYS A 1 415 ? 175.794 130.664 162.478 1.00 120.55 ? 415 CYS A O   1 
ATOM   1541 C CB  . CYS A 1 415 ? 177.827 131.985 160.303 1.00 116.83 ? 415 CYS A CB  1 
ATOM   1542 S SG  . CYS A 1 415 ? 179.203 131.628 159.189 1.00 124.36 ? 415 CYS A SG  1 
ATOM   1543 N N   . PHE A 1 416 ? 174.730 132.103 161.109 1.00 113.93 ? 416 PHE A N   1 
ATOM   1544 C CA  . PHE A 1 416 ? 173.681 132.406 162.074 1.00 114.56 ? 416 PHE A CA  1 
ATOM   1545 C C   . PHE A 1 416 ? 172.875 131.158 162.405 1.00 118.74 ? 416 PHE A C   1 
ATOM   1546 O O   . PHE A 1 416 ? 172.635 130.850 163.576 1.00 123.43 ? 416 PHE A O   1 
ATOM   1547 C CB  . PHE A 1 416 ? 172.775 133.501 161.504 1.00 115.11 ? 416 PHE A CB  1 
ATOM   1548 C CG  . PHE A 1 416 ? 171.996 134.270 162.538 1.00 117.33 ? 416 PHE A CG  1 
ATOM   1549 C CD1 . PHE A 1 416 ? 171.830 133.787 163.824 1.00 123.07 ? 416 PHE A CD1 1 
ATOM   1550 C CD2 . PHE A 1 416 ? 171.422 135.485 162.209 1.00 109.96 ? 416 PHE A CD2 1 
ATOM   1551 C CE1 . PHE A 1 416 ? 171.110 134.500 164.761 1.00 126.97 ? 416 PHE A CE1 1 
ATOM   1552 C CE2 . PHE A 1 416 ? 170.703 136.202 163.141 1.00 111.34 ? 416 PHE A CE2 1 
ATOM   1553 C CZ  . PHE A 1 416 ? 170.547 135.710 164.418 1.00 124.77 ? 416 PHE A CZ  1 
ATOM   1554 N N   . TYR A 1 417 ? 172.463 130.416 161.378 1.00 117.95 ? 417 TYR A N   1 
ATOM   1555 C CA  . TYR A 1 417 ? 171.649 129.229 161.612 1.00 119.67 ? 417 TYR A CA  1 
ATOM   1556 C C   . TYR A 1 417 ? 172.474 128.075 162.167 1.00 121.15 ? 417 TYR A C   1 
ATOM   1557 O O   . TYR A 1 417 ? 171.913 127.143 162.753 1.00 122.59 ? 417 TYR A O   1 
ATOM   1558 C CB  . TYR A 1 417 ? 170.946 128.819 160.320 1.00 119.00 ? 417 TYR A CB  1 
ATOM   1559 C CG  . TYR A 1 417 ? 169.951 129.845 159.828 1.00 117.99 ? 417 TYR A CG  1 
ATOM   1560 C CD1 . TYR A 1 417 ? 169.283 130.674 160.719 1.00 116.09 ? 417 TYR A CD1 1 
ATOM   1561 C CD2 . TYR A 1 417 ? 169.685 129.991 158.474 1.00 114.83 ? 417 TYR A CD2 1 
ATOM   1562 C CE1 . TYR A 1 417 ? 168.374 131.615 160.276 1.00 110.16 ? 417 TYR A CE1 1 
ATOM   1563 C CE2 . TYR A 1 417 ? 168.776 130.932 158.023 1.00 113.28 ? 417 TYR A CE2 1 
ATOM   1564 C CZ  . TYR A 1 417 ? 168.124 131.739 158.930 1.00 109.58 ? 417 TYR A CZ  1 
ATOM   1565 O OH  . TYR A 1 417 ? 167.219 132.677 158.492 1.00 104.00 ? 417 TYR A OH  1 
ATOM   1566 N N   . SER A 1 418 ? 173.797 128.114 161.998 1.00 119.20 ? 418 SER A N   1 
ATOM   1567 C CA  . SER A 1 418 ? 174.627 127.017 162.481 1.00 121.45 ? 418 SER A CA  1 
ATOM   1568 C C   . SER A 1 418 ? 175.075 127.227 163.923 1.00 125.52 ? 418 SER A C   1 
ATOM   1569 O O   . SER A 1 418 ? 175.190 126.260 164.684 1.00 129.17 ? 418 SER A O   1 
ATOM   1570 C CB  . SER A 1 418 ? 175.840 126.844 161.567 1.00 120.61 ? 418 SER A CB  1 
ATOM   1571 O OG  . SER A 1 418 ? 175.437 126.628 160.227 1.00 120.26 ? 418 SER A OG  1 
ATOM   1572 N N   . LEU A 1 419 ? 175.338 128.473 164.317 1.00 124.31 ? 419 LEU A N   1 
ATOM   1573 C CA  . LEU A 1 419 ? 175.883 128.766 165.637 1.00 125.34 ? 419 LEU A CA  1 
ATOM   1574 C C   . LEU A 1 419 ? 174.904 129.454 166.574 1.00 125.78 ? 419 LEU A C   1 
ATOM   1575 O O   . LEU A 1 419 ? 174.950 129.206 167.780 1.00 125.34 ? 419 LEU A O   1 
ATOM   1576 C CB  . LEU A 1 419 ? 177.138 129.640 165.509 1.00 124.43 ? 419 LEU A CB  1 
ATOM   1577 C CG  . LEU A 1 419 ? 178.281 129.061 164.672 1.00 122.68 ? 419 LEU A CG  1 
ATOM   1578 C CD1 . LEU A 1 419 ? 179.425 130.056 164.554 1.00 118.25 ? 419 LEU A CD1 1 
ATOM   1579 C CD2 . LEU A 1 419 ? 178.771 127.750 165.268 1.00 122.38 ? 419 LEU A CD2 1 
ATOM   1580 N N   . GLU A 1 420 ? 174.028 130.305 166.058 1.00 127.07 ? 420 GLU A N   1 
ATOM   1581 C CA  . GLU A 1 420 ? 173.083 131.063 166.866 1.00 130.86 ? 420 GLU A CA  1 
ATOM   1582 C C   . GLU A 1 420 ? 171.659 130.676 166.473 1.00 131.78 ? 420 GLU A C   1 
ATOM   1583 O O   . GLU A 1 420 ? 171.437 129.697 165.755 1.00 130.85 ? 420 GLU A O   1 
ATOM   1584 C CB  . GLU A 1 420 ? 173.327 132.566 166.715 1.00 129.66 ? 420 GLU A CB  1 
ATOM   1585 C CG  . GLU A 1 420 ? 174.702 133.023 167.165 1.00 131.18 ? 420 GLU A CG  1 
ATOM   1586 C CD  . GLU A 1 420 ? 174.880 134.522 167.055 1.00 131.58 ? 420 GLU A CD  1 
ATOM   1587 O OE1 . GLU A 1 420 ? 173.907 135.211 166.682 1.00 129.62 ? 420 GLU A OE1 1 
ATOM   1588 O OE2 . GLU A 1 420 ? 175.991 135.013 167.342 1.00 132.47 ? 420 GLU A OE2 1 
ATOM   1589 N N   . LEU A 1 421 ? 170.690 131.445 166.972 1.00 132.15 ? 421 LEU A N   1 
ATOM   1590 C CA  . LEU A 1 421 ? 169.271 131.212 166.707 1.00 134.28 ? 421 LEU A CA  1 
ATOM   1591 C C   . LEU A 1 421 ? 168.865 129.807 167.164 1.00 139.71 ? 421 LEU A C   1 
ATOM   1592 O O   . LEU A 1 421 ? 168.561 128.916 166.371 1.00 139.68 ? 421 LEU A O   1 
ATOM   1593 C CB  . LEU A 1 421 ? 168.941 131.436 165.227 1.00 130.36 ? 421 LEU A CB  1 
ATOM   1594 C CG  . LEU A 1 421 ? 167.445 131.572 164.951 1.00 131.59 ? 421 LEU A CG  1 
ATOM   1595 C CD1 . LEU A 1 421 ? 166.914 132.869 165.542 1.00 130.36 ? 421 LEU A CD1 1 
ATOM   1596 C CD2 . LEU A 1 421 ? 167.160 131.494 163.467 1.00 128.64 ? 421 LEU A CD2 1 
ATOM   1597 N N   . LYS A 1 422 ? 168.893 129.641 168.490 1.00 142.33 ? 422 LYS A N   1 
ATOM   1598 C CA  . LYS A 1 422 ? 168.681 128.345 169.127 1.00 144.20 ? 422 LYS A CA  1 
ATOM   1599 C C   . LYS A 1 422 ? 167.404 127.644 168.678 1.00 144.26 ? 422 LYS A C   1 
ATOM   1600 O O   . LYS A 1 422 ? 167.233 126.454 168.969 1.00 146.34 ? 422 LYS A O   1 
ATOM   1601 C CB  . LYS A 1 422 ? 168.653 128.524 170.648 1.00 144.44 ? 422 LYS A CB  1 
ATOM   1602 C CG  . LYS A 1 422 ? 169.723 129.464 171.178 1.00 143.22 ? 422 LYS A CG  1 
ATOM   1603 C CD  . LYS A 1 422 ? 169.467 129.833 172.631 1.00 145.03 ? 422 LYS A CD  1 
ATOM   1604 C CE  . LYS A 1 422 ? 170.405 130.937 173.091 1.00 143.43 ? 422 LYS A CE  1 
ATOM   1605 N NZ  . LYS A 1 422 ? 170.097 131.388 174.475 1.00 140.81 ? 422 LYS A NZ  1 
ATOM   1606 N N   . TRP A 1 423 ? 166.499 128.353 168.004 1.00 140.40 ? 423 TRP A N   1 
ATOM   1607 C CA  . TRP A 1 423 ? 165.205 127.892 167.499 1.00 140.49 ? 423 TRP A CA  1 
ATOM   1608 C C   . TRP A 1 423 ? 164.197 127.710 168.627 1.00 143.50 ? 423 TRP A C   1 
ATOM   1609 O O   . TRP A 1 423 ? 163.022 127.445 168.346 1.00 143.23 ? 423 TRP A O   1 
ATOM   1610 C CB  . TRP A 1 423 ? 165.281 126.577 166.703 1.00 139.86 ? 423 TRP A CB  1 
ATOM   1611 C CG  . TRP A 1 423 ? 166.316 126.554 165.624 1.00 137.82 ? 423 TRP A CG  1 
ATOM   1612 C CD1 . TRP A 1 423 ? 167.623 126.192 165.752 1.00 140.50 ? 423 TRP A CD1 1 
ATOM   1613 C CD2 . TRP A 1 423 ? 166.125 126.883 164.244 1.00 133.30 ? 423 TRP A CD2 1 
ATOM   1614 N NE1 . TRP A 1 423 ? 168.263 126.288 164.541 1.00 139.64 ? 423 TRP A NE1 1 
ATOM   1615 C CE2 . TRP A 1 423 ? 167.364 126.709 163.599 1.00 136.10 ? 423 TRP A CE2 1 
ATOM   1616 C CE3 . TRP A 1 423 ? 165.029 127.312 163.493 1.00 130.16 ? 423 TRP A CE3 1 
ATOM   1617 C CZ2 . TRP A 1 423 ? 167.536 126.950 162.239 1.00 131.48 ? 423 TRP A CZ2 1 
ATOM   1618 C CZ3 . TRP A 1 423 ? 165.202 127.550 162.144 1.00 131.85 ? 423 TRP A CZ3 1 
ATOM   1619 C CH2 . TRP A 1 423 ? 166.445 127.368 161.531 1.00 130.27 ? 423 TRP A CH2 1 
ATOM   1620 N N   . ASP A 1 424 ? 164.606 127.840 169.888 1.00 144.64 ? 424 ASP A N   1 
ATOM   1621 C CA  . ASP A 1 424 ? 163.689 127.696 171.011 1.00 143.62 ? 424 ASP A CA  1 
ATOM   1622 C C   . ASP A 1 424 ? 162.972 129.000 171.330 1.00 142.76 ? 424 ASP A C   1 
ATOM   1623 O O   . ASP A 1 424 ? 161.791 128.985 171.694 1.00 140.22 ? 424 ASP A O   1 
ATOM   1624 C CB  . ASP A 1 424 ? 164.442 127.201 172.248 1.00 145.99 ? 424 ASP A CB  1 
ATOM   1625 C CG  . ASP A 1 424 ? 165.210 125.919 171.987 1.00 148.47 ? 424 ASP A CG  1 
ATOM   1626 O OD1 . ASP A 1 424 ? 165.211 125.450 170.830 1.00 147.98 ? 424 ASP A OD1 1 
ATOM   1627 O OD2 . ASP A 1 424 ? 165.813 125.381 172.940 1.00 148.15 ? 424 ASP A OD2 1 
ATOM   1628 N N   . GLU A 1 425 ? 163.665 130.127 171.199 1.00 146.01 ? 425 GLU A N   1 
ATOM   1629 C CA  . GLU A 1 425 ? 163.061 131.427 171.448 1.00 146.57 ? 425 GLU A CA  1 
ATOM   1630 C C   . GLU A 1 425 ? 162.347 131.926 170.200 1.00 144.14 ? 425 GLU A C   1 
ATOM   1631 O O   . GLU A 1 425 ? 162.830 131.753 169.078 1.00 143.19 ? 425 GLU A O   1 
ATOM   1632 C CB  . GLU A 1 425 ? 164.127 132.434 171.880 1.00 146.19 ? 425 GLU A CB  1 
ATOM   1633 C CG  . GLU A 1 425 ? 164.898 132.021 173.120 1.00 148.70 ? 425 GLU A CG  1 
ATOM   1634 C CD  . GLU A 1 425 ? 165.977 133.017 173.493 1.00 151.10 ? 425 GLU A CD  1 
ATOM   1635 O OE1 . GLU A 1 425 ? 166.320 133.870 172.647 1.00 147.02 ? 425 GLU A OE1 1 
ATOM   1636 O OE2 . GLU A 1 425 ? 166.480 132.948 174.635 1.00 154.53 ? 425 GLU A OE2 1 
ATOM   1637 N N   . SER A 1 426 ? 161.186 132.551 170.403 1.00 141.27 ? 426 SER A N   1 
ATOM   1638 C CA  . SER A 1 426 ? 160.417 133.088 169.287 1.00 136.49 ? 426 SER A CA  1 
ATOM   1639 C C   . SER A 1 426 ? 161.040 134.341 168.689 1.00 135.39 ? 426 SER A C   1 
ATOM   1640 O O   . SER A 1 426 ? 160.580 134.795 167.637 1.00 130.15 ? 426 SER A O   1 
ATOM   1641 C CB  . SER A 1 426 ? 158.985 133.391 169.731 1.00 138.62 ? 426 SER A CB  1 
ATOM   1642 O OG  . SER A 1 426 ? 158.962 134.409 170.717 1.00 139.67 ? 426 SER A OG  1 
ATOM   1643 N N   . LYS A 1 427 ? 162.060 134.910 169.327 1.00 140.44 ? 427 LYS A N   1 
ATOM   1644 C CA  . LYS A 1 427 ? 162.708 136.118 168.828 1.00 139.48 ? 427 LYS A CA  1 
ATOM   1645 C C   . LYS A 1 427 ? 163.793 135.730 167.831 1.00 137.41 ? 427 LYS A C   1 
ATOM   1646 O O   . LYS A 1 427 ? 164.787 135.096 168.198 1.00 138.30 ? 427 LYS A O   1 
ATOM   1647 C CB  . LYS A 1 427 ? 163.290 136.927 169.984 1.00 139.44 ? 427 LYS A CB  1 
ATOM   1648 C CG  . LYS A 1 427 ? 162.252 137.450 170.959 1.00 140.48 ? 427 LYS A CG  1 
ATOM   1649 C CD  . LYS A 1 427 ? 162.895 138.276 172.060 1.00 140.82 ? 427 LYS A CD  1 
ATOM   1650 C CE  . LYS A 1 427 ? 161.846 138.854 172.999 1.00 139.78 ? 427 LYS A CE  1 
ATOM   1651 N NZ  . LYS A 1 427 ? 161.007 137.791 173.617 1.00 138.38 ? 427 LYS A NZ  1 
ATOM   1652 N N   . GLY A 1 428 ? 163.607 136.113 166.569 1.00 132.53 ? 428 GLY A N   1 
ATOM   1653 C CA  . GLY A 1 428 ? 164.619 135.878 165.558 1.00 127.39 ? 428 GLY A CA  1 
ATOM   1654 C C   . GLY A 1 428 ? 165.750 136.879 165.549 1.00 123.60 ? 428 GLY A C   1 
ATOM   1655 O O   . GLY A 1 428 ? 166.712 136.705 164.794 1.00 118.14 ? 428 GLY A O   1 
ATOM   1656 N N   . LEU A 1 429 ? 165.654 137.924 166.368 1.00 126.63 ? 429 LEU A N   1 
ATOM   1657 C CA  . LEU A 1 429 ? 166.698 138.934 166.473 1.00 129.27 ? 429 LEU A CA  1 
ATOM   1658 C C   . LEU A 1 429 ? 167.658 138.681 167.625 1.00 135.54 ? 429 LEU A C   1 
ATOM   1659 O O   . LEU A 1 429 ? 168.821 139.092 167.545 1.00 133.80 ? 429 LEU A O   1 
ATOM   1660 C CB  . LEU A 1 429 ? 166.079 140.327 166.644 1.00 127.63 ? 429 LEU A CB  1 
ATOM   1661 C CG  . LEU A 1 429 ? 165.335 140.985 165.478 1.00 118.34 ? 429 LEU A CG  1 
ATOM   1662 C CD1 . LEU A 1 429 ? 163.943 140.402 165.288 1.00 109.54 ? 429 LEU A CD1 1 
ATOM   1663 C CD2 . LEU A 1 429 ? 165.257 142.487 165.693 1.00 113.73 ? 429 LEU A CD2 1 
ATOM   1664 N N   . LEU A 1 430 ? 167.188 138.027 168.694 1.00 140.83 ? 430 LEU A N   1 
ATOM   1665 C CA  . LEU A 1 430 ? 167.945 137.685 169.895 1.00 142.22 ? 430 LEU A CA  1 
ATOM   1666 C C   . LEU A 1 430 ? 168.322 138.939 170.676 1.00 141.57 ? 430 LEU A C   1 
ATOM   1667 O O   . LEU A 1 430 ? 168.588 139.991 170.082 1.00 135.61 ? 430 LEU A O   1 
ATOM   1668 C CB  . LEU A 1 430 ? 169.199 136.877 169.545 1.00 140.81 ? 430 LEU A CB  1 
ATOM   1669 C CG  . LEU A 1 430 ? 168.982 135.531 168.850 1.00 136.32 ? 430 LEU A CG  1 
ATOM   1670 C CD1 . LEU A 1 430 ? 170.310 134.817 168.648 1.00 132.67 ? 430 LEU A CD1 1 
ATOM   1671 C CD2 . LEU A 1 430 ? 168.016 134.659 169.637 1.00 137.68 ? 430 LEU A CD2 1 
ATOM   1672 N N   . PRO A 1 431 ? 168.356 138.872 172.015 1.00 145.04 ? 431 PRO A N   1 
ATOM   1673 C CA  . PRO A 1 431 ? 168.738 140.029 172.829 1.00 144.12 ? 431 PRO A CA  1 
ATOM   1674 C C   . PRO A 1 431 ? 170.234 140.323 172.752 1.00 139.39 ? 431 PRO A C   1 
ATOM   1675 O O   . PRO A 1 431 ? 170.769 140.954 173.663 1.00 135.39 ? 431 PRO A O   1 
ATOM   1676 C CB  . PRO A 1 431 ? 168.333 139.609 174.244 1.00 144.10 ? 431 PRO A CB  1 
ATOM   1677 C CG  . PRO A 1 431 ? 168.404 138.124 174.222 1.00 143.40 ? 431 PRO A CG  1 
ATOM   1678 C CD  . PRO A 1 431 ? 167.972 137.715 172.843 1.00 143.55 ? 431 PRO A CD  1 
ATOM   1679 N N   . GLY A 1 446 ? 188.970 133.274 158.663 1.00 96.54  ? 446 GLY A N   1 
ATOM   1680 C CA  . GLY A 1 446 ? 189.407 133.299 157.279 1.00 93.82  ? 446 GLY A CA  1 
ATOM   1681 C C   . GLY A 1 446 ? 188.403 132.678 156.331 1.00 93.35  ? 446 GLY A C   1 
ATOM   1682 O O   . GLY A 1 446 ? 188.598 132.678 155.117 1.00 93.40  ? 446 GLY A O   1 
ATOM   1683 N N   . VAL A 1 447 ? 187.322 132.137 156.895 1.00 93.67  ? 447 VAL A N   1 
ATOM   1684 C CA  . VAL A 1 447 ? 186.295 131.511 156.069 1.00 95.31  ? 447 VAL A CA  1 
ATOM   1685 C C   . VAL A 1 447 ? 185.578 132.546 155.214 1.00 97.22  ? 447 VAL A C   1 
ATOM   1686 O O   . VAL A 1 447 ? 185.176 132.254 154.081 1.00 94.62  ? 447 VAL A O   1 
ATOM   1687 C CB  . VAL A 1 447 ? 185.312 130.720 156.950 1.00 93.22  ? 447 VAL A CB  1 
ATOM   1688 C CG1 . VAL A 1 447 ? 186.005 129.510 157.550 1.00 94.96  ? 447 VAL A CG1 1 
ATOM   1689 C CG2 . VAL A 1 447 ? 184.746 131.605 158.047 1.00 93.19  ? 447 VAL A CG2 1 
ATOM   1690 N N   . ARG A 1 448 ? 185.391 133.759 155.734 1.00 98.46  ? 448 ARG A N   1 
ATOM   1691 C CA  . ARG A 1 448 ? 184.725 134.801 154.962 1.00 97.28  ? 448 ARG A CA  1 
ATOM   1692 C C   . ARG A 1 448 ? 185.645 135.382 153.895 1.00 94.66  ? 448 ARG A C   1 
ATOM   1693 O O   . ARG A 1 448 ? 185.178 135.809 152.833 1.00 95.25  ? 448 ARG A O   1 
ATOM   1694 C CB  . ARG A 1 448 ? 184.229 135.904 155.895 1.00 101.79 ? 448 ARG A CB  1 
ATOM   1695 C CG  . ARG A 1 448 ? 183.517 135.391 157.133 1.00 110.32 ? 448 ARG A CG  1 
ATOM   1696 C CD  . ARG A 1 448 ? 183.021 136.539 157.993 1.00 117.73 ? 448 ARG A CD  1 
ATOM   1697 N NE  . ARG A 1 448 ? 181.931 137.266 157.356 1.00 124.98 ? 448 ARG A NE  1 
ATOM   1698 C CZ  . ARG A 1 448 ? 181.412 138.394 157.821 1.00 127.30 ? 448 ARG A CZ  1 
ATOM   1699 N NH1 . ARG A 1 448 ? 181.876 138.966 158.919 1.00 125.38 ? 448 ARG A NH1 1 
ATOM   1700 N NH2 . ARG A 1 448 ? 180.405 138.963 157.166 1.00 124.24 ? 448 ARG A NH2 1 
ATOM   1701 N N   . ALA A 1 449 ? 186.952 135.409 154.161 1.00 91.91  ? 449 ALA A N   1 
ATOM   1702 C CA  . ALA A 1 449 ? 187.885 136.029 153.226 1.00 88.94  ? 449 ALA A CA  1 
ATOM   1703 C C   . ALA A 1 449 ? 187.906 135.297 151.890 1.00 86.13  ? 449 ALA A C   1 
ATOM   1704 O O   . ALA A 1 449 ? 187.940 135.930 150.829 1.00 81.44  ? 449 ALA A O   1 
ATOM   1705 C CB  . ALA A 1 449 ? 189.284 136.075 153.836 1.00 91.80  ? 449 ALA A CB  1 
ATOM   1706 N N   . ILE A 1 450 ? 187.891 133.964 151.921 1.00 87.49  ? 450 ILE A N   1 
ATOM   1707 C CA  . ILE A 1 450 ? 187.993 133.199 150.682 1.00 85.76  ? 450 ILE A CA  1 
ATOM   1708 C C   . ILE A 1 450 ? 186.720 133.339 149.857 1.00 80.95  ? 450 ILE A C   1 
ATOM   1709 O O   . ILE A 1 450 ? 186.776 133.496 148.632 1.00 79.48  ? 450 ILE A O   1 
ATOM   1710 C CB  . ILE A 1 450 ? 188.324 131.726 150.988 1.00 84.59  ? 450 ILE A CB  1 
ATOM   1711 C CG1 . ILE A 1 450 ? 188.259 130.880 149.714 1.00 83.83  ? 450 ILE A CG1 1 
ATOM   1712 C CG2 . ILE A 1 450 ? 187.403 131.173 152.064 1.00 86.42  ? 450 ILE A CG2 1 
ATOM   1713 C CD1 . ILE A 1 450 ? 189.260 131.286 148.654 1.00 80.65  ? 450 ILE A CD1 1 
ATOM   1714 N N   . VAL A 1 451 ? 185.555 133.292 150.506 1.00 81.46  ? 451 VAL A N   1 
ATOM   1715 C CA  . VAL A 1 451 ? 184.310 133.450 149.764 1.00 82.26  ? 451 VAL A CA  1 
ATOM   1716 C C   . VAL A 1 451 ? 184.172 134.879 149.255 1.00 81.17  ? 451 VAL A C   1 
ATOM   1717 O O   . VAL A 1 451 ? 183.507 135.122 148.241 1.00 77.13  ? 451 VAL A O   1 
ATOM   1718 C CB  . VAL A 1 451 ? 183.106 133.025 150.628 1.00 83.54  ? 451 VAL A CB  1 
ATOM   1719 C CG1 . VAL A 1 451 ? 182.912 133.971 151.794 1.00 87.36  ? 451 VAL A CG1 1 
ATOM   1720 C CG2 . VAL A 1 451 ? 181.844 132.946 149.787 1.00 79.12  ? 451 VAL A CG2 1 
ATOM   1721 N N   . GLN A 1 452 ? 184.806 135.842 149.929 1.00 81.24  ? 452 GLN A N   1 
ATOM   1722 C CA  . GLN A 1 452 ? 184.777 137.219 149.451 1.00 77.84  ? 452 GLN A CA  1 
ATOM   1723 C C   . GLN A 1 452 ? 185.445 137.353 148.089 1.00 79.63  ? 452 GLN A C   1 
ATOM   1724 O O   . GLN A 1 452 ? 185.050 138.205 147.285 1.00 78.03  ? 452 GLN A O   1 
ATOM   1725 C CB  . GLN A 1 452 ? 185.448 138.136 150.473 1.00 78.60  ? 452 GLN A CB  1 
ATOM   1726 C CG  . GLN A 1 452 ? 185.576 139.582 150.037 1.00 82.61  ? 452 GLN A CG  1 
ATOM   1727 C CD  . GLN A 1 452 ? 184.236 140.253 149.837 1.00 84.90  ? 452 GLN A CD  1 
ATOM   1728 O OE1 . GLN A 1 452 ? 183.698 140.274 148.731 1.00 85.87  ? 452 GLN A OE1 1 
ATOM   1729 N NE2 . GLN A 1 452 ? 183.689 140.811 150.908 1.00 85.71  ? 452 GLN A NE2 1 
ATOM   1730 N N   . CYS A 1 453 ? 186.443 136.520 147.804 1.00 82.08  ? 453 CYS A N   1 
ATOM   1731 C CA  . CYS A 1 453 ? 187.152 136.560 146.533 1.00 77.92  ? 453 CYS A CA  1 
ATOM   1732 C C   . CYS A 1 453 ? 186.503 135.704 145.455 1.00 75.80  ? 453 CYS A C   1 
ATOM   1733 O O   . CYS A 1 453 ? 187.004 135.681 144.326 1.00 70.07  ? 453 CYS A O   1 
ATOM   1734 C CB  . CYS A 1 453 ? 188.602 136.110 146.721 1.00 78.37  ? 453 CYS A CB  1 
ATOM   1735 S SG  . CYS A 1 453 ? 189.506 137.027 147.971 1.00 82.03  ? 453 CYS A SG  1 
ATOM   1736 N N   . ILE A 1 454 ? 185.420 134.990 145.773 1.00 75.64  ? 454 ILE A N   1 
ATOM   1737 C CA  . ILE A 1 454 ? 184.754 134.163 144.763 1.00 72.45  ? 454 ILE A CA  1 
ATOM   1738 C C   . ILE A 1 454 ? 184.295 134.985 143.565 1.00 72.26  ? 454 ILE A C   1 
ATOM   1739 O O   . ILE A 1 454 ? 184.553 134.567 142.422 1.00 71.61  ? 454 ILE A O   1 
ATOM   1740 C CB  . ILE A 1 454 ? 183.612 133.359 145.404 1.00 68.37  ? 454 ILE A CB  1 
ATOM   1741 C CG1 . ILE A 1 454 ? 184.170 132.292 146.340 1.00 76.13  ? 454 ILE A CG1 1 
ATOM   1742 C CG2 . ILE A 1 454 ? 182.762 132.704 144.333 1.00 65.50  ? 454 ILE A CG2 1 
ATOM   1743 C CD1 . ILE A 1 454 ? 184.905 131.181 145.622 1.00 74.81  ? 454 ILE A CD1 1 
ATOM   1744 N N   . PRO A 1 455 ? 183.631 136.147 143.729 1.00 69.44  ? 455 PRO A N   1 
ATOM   1745 C CA  . PRO A 1 455 ? 183.249 136.934 142.550 1.00 68.35  ? 455 PRO A CA  1 
ATOM   1746 C C   . PRO A 1 455 ? 184.452 137.402 141.747 1.00 69.05  ? 455 PRO A C   1 
ATOM   1747 O O   . PRO A 1 455 ? 184.334 137.702 140.556 1.00 68.98  ? 455 PRO A O   1 
ATOM   1748 C CB  . PRO A 1 455 ? 182.481 138.114 143.153 1.00 67.44  ? 455 PRO A CB  1 
ATOM   1749 C CG  . PRO A 1 455 ? 181.988 137.618 144.452 1.00 66.51  ? 455 PRO A CG  1 
ATOM   1750 C CD  . PRO A 1 455 ? 183.078 136.738 144.962 1.00 67.57  ? 455 PRO A CD  1 
ATOM   1751 N N   . ALA A 1 456 ? 185.614 137.467 142.392 1.00 69.44  ? 456 ALA A N   1 
ATOM   1752 C CA  . ALA A 1 456 ? 186.861 137.796 141.719 1.00 68.47  ? 456 ALA A CA  1 
ATOM   1753 C C   . ALA A 1 456 ? 187.632 136.579 141.241 1.00 65.87  ? 456 ALA A C   1 
ATOM   1754 O O   . ALA A 1 456 ? 188.334 136.672 140.233 1.00 66.74  ? 456 ALA A O   1 
ATOM   1755 C CB  . ALA A 1 456 ? 187.771 138.619 142.640 1.00 71.57  ? 456 ALA A CB  1 
ATOM   1756 N N   . TRP A 1 457 ? 187.529 135.448 141.934 1.00 63.32  ? 457 TRP A N   1 
ATOM   1757 C CA  . TRP A 1 457 ? 188.190 134.240 141.466 1.00 67.52  ? 457 TRP A CA  1 
ATOM   1758 C C   . TRP A 1 457 ? 187.523 133.735 140.200 1.00 67.10  ? 457 TRP A C   1 
ATOM   1759 O O   . TRP A 1 457 ? 188.190 133.181 139.323 1.00 70.42  ? 457 TRP A O   1 
ATOM   1760 C CB  . TRP A 1 457 ? 188.173 133.146 142.528 1.00 71.60  ? 457 TRP A CB  1 
ATOM   1761 C CG  . TRP A 1 457 ? 188.738 131.872 142.013 1.00 67.82  ? 457 TRP A CG  1 
ATOM   1762 C CD1 . TRP A 1 457 ? 188.046 130.786 141.578 1.00 65.13  ? 457 TRP A CD1 1 
ATOM   1763 C CD2 . TRP A 1 457 ? 190.123 131.560 141.848 1.00 65.53  ? 457 TRP A CD2 1 
ATOM   1764 N NE1 . TRP A 1 457 ? 188.914 129.807 141.165 1.00 65.95  ? 457 TRP A NE1 1 
ATOM   1765 C CE2 . TRP A 1 457 ? 190.196 130.259 141.322 1.00 64.95  ? 457 TRP A CE2 1 
ATOM   1766 C CE3 . TRP A 1 457 ? 191.310 132.252 142.104 1.00 69.25  ? 457 TRP A CE3 1 
ATOM   1767 C CZ2 . TRP A 1 457 ? 191.407 129.636 141.045 1.00 69.10  ? 457 TRP A CZ2 1 
ATOM   1768 C CZ3 . TRP A 1 457 ? 192.509 131.633 141.828 1.00 74.99  ? 457 TRP A CZ3 1 
ATOM   1769 C CH2 . TRP A 1 457 ? 192.550 130.339 141.304 1.00 76.18  ? 457 TRP A CH2 1 
ATOM   1770 N N   . LEU A 1 458 ? 186.208 133.920 140.096 1.00 64.35  ? 458 LEU A N   1 
ATOM   1771 C CA  . LEU A 1 458 ? 185.484 133.504 138.905 1.00 66.90  ? 458 LEU A CA  1 
ATOM   1772 C C   . LEU A 1 458 ? 185.753 134.395 137.706 1.00 64.10  ? 458 LEU A C   1 
ATOM   1773 O O   . LEU A 1 458 ? 185.386 134.028 136.584 1.00 60.74  ? 458 LEU A O   1 
ATOM   1774 C CB  . LEU A 1 458 ? 183.976 133.477 139.178 1.00 61.58  ? 458 LEU A CB  1 
ATOM   1775 C CG  . LEU A 1 458 ? 183.534 132.496 140.259 1.00 66.66  ? 458 LEU A CG  1 
ATOM   1776 C CD1 . LEU A 1 458 ? 182.035 132.572 140.467 1.00 72.65  ? 458 LEU A CD1 1 
ATOM   1777 C CD2 . LEU A 1 458 ? 183.963 131.086 139.898 1.00 70.64  ? 458 LEU A CD2 1 
ATOM   1778 N N   . ARG A 1 459 ? 186.383 135.546 137.914 1.00 63.82  ? 459 ARG A N   1 
ATOM   1779 C CA  . ARG A 1 459 ? 186.698 136.473 136.842 1.00 60.04  ? 459 ARG A CA  1 
ATOM   1780 C C   . ARG A 1 459 ? 188.186 136.509 136.525 1.00 63.00  ? 459 ARG A C   1 
ATOM   1781 O O   . ARG A 1 459 ? 188.561 136.882 135.410 1.00 68.81  ? 459 ARG A O   1 
ATOM   1782 C CB  . ARG A 1 459 ? 186.189 137.874 137.208 1.00 55.77  ? 459 ARG A CB  1 
ATOM   1783 C CG  . ARG A 1 459 ? 186.257 138.887 136.087 1.00 56.68  ? 459 ARG A CG  1 
ATOM   1784 C CD  . ARG A 1 459 ? 185.280 138.597 134.977 1.00 51.44  ? 459 ARG A CD  1 
ATOM   1785 N NE  . ARG A 1 459 ? 185.632 139.342 133.775 1.00 51.01  ? 459 ARG A NE  1 
ATOM   1786 C CZ  . ARG A 1 459 ? 186.276 138.824 132.740 1.00 51.82  ? 459 ARG A CZ  1 
ATOM   1787 N NH1 . ARG A 1 459 ? 186.600 137.545 132.701 1.00 53.09  ? 459 ARG A NH1 1 
ATOM   1788 N NH2 . ARG A 1 459 ? 186.603 139.609 131.720 1.00 55.99  ? 459 ARG A NH2 1 
ATOM   1789 N N   . PHE A 1 460 ? 189.043 136.133 137.470 1.00 61.44  ? 460 PHE A N   1 
ATOM   1790 C CA  . PHE A 1 460 ? 190.462 135.968 137.181 1.00 64.47  ? 460 PHE A CA  1 
ATOM   1791 C C   . PHE A 1 460 ? 190.745 134.733 136.337 1.00 67.74  ? 460 PHE A C   1 
ATOM   1792 O O   . PHE A 1 460 ? 191.473 134.823 135.339 1.00 66.84  ? 460 PHE A O   1 
ATOM   1793 C CB  . PHE A 1 460 ? 191.256 135.900 138.491 1.00 65.74  ? 460 PHE A CB  1 
ATOM   1794 C CG  . PHE A 1 460 ? 192.675 135.437 138.324 1.00 67.34  ? 460 PHE A CG  1 
ATOM   1795 C CD1 . PHE A 1 460 ? 193.542 136.096 137.469 1.00 69.53  ? 460 PHE A CD1 1 
ATOM   1796 C CD2 . PHE A 1 460 ? 193.148 134.354 139.039 1.00 66.99  ? 460 PHE A CD2 1 
ATOM   1797 C CE1 . PHE A 1 460 ? 194.847 135.668 137.322 1.00 72.47  ? 460 PHE A CE1 1 
ATOM   1798 C CE2 . PHE A 1 460 ? 194.451 133.925 138.895 1.00 68.75  ? 460 PHE A CE2 1 
ATOM   1799 C CZ  . PHE A 1 460 ? 195.301 134.585 138.038 1.00 70.95  ? 460 PHE A CZ  1 
ATOM   1800 N N   . ILE A 1 461 ? 190.175 133.585 136.704 1.00 70.32  ? 461 ILE A N   1 
ATOM   1801 C CA  . ILE A 1 461 ? 190.324 132.386 135.889 1.00 68.03  ? 461 ILE A CA  1 
ATOM   1802 C C   . ILE A 1 461 ? 189.639 132.531 134.539 1.00 64.51  ? 461 ILE A C   1 
ATOM   1803 O O   . ILE A 1 461 ? 190.094 131.928 133.558 1.00 60.73  ? 461 ILE A O   1 
ATOM   1804 C CB  . ILE A 1 461 ? 189.790 131.141 136.619 1.00 67.01  ? 461 ILE A CB  1 
ATOM   1805 C CG1 . ILE A 1 461 ? 188.287 131.258 136.866 1.00 71.61  ? 461 ILE A CG1 1 
ATOM   1806 C CG2 . ILE A 1 461 ? 190.527 130.943 137.927 1.00 66.99  ? 461 ILE A CG2 1 
ATOM   1807 C CD1 . ILE A 1 461 ? 187.760 130.289 137.905 1.00 77.05  ? 461 ILE A CD1 1 
ATOM   1808 N N   . GLN A 1 462 ? 188.569 133.318 134.456 1.00 65.03  ? 462 GLN A N   1 
ATOM   1809 C CA  . GLN A 1 462 ? 187.936 133.591 133.175 1.00 65.04  ? 462 GLN A CA  1 
ATOM   1810 C C   . GLN A 1 462 ? 188.862 134.344 132.232 1.00 64.70  ? 462 GLN A C   1 
ATOM   1811 O O   . GLN A 1 462 ? 188.956 133.984 131.054 1.00 64.39  ? 462 GLN A O   1 
ATOM   1812 C CB  . GLN A 1 462 ? 186.649 134.377 133.405 1.00 61.82  ? 462 GLN A CB  1 
ATOM   1813 C CG  . GLN A 1 462 ? 185.674 134.342 132.259 1.00 56.32  ? 462 GLN A CG  1 
ATOM   1814 C CD  . GLN A 1 462 ? 184.249 134.488 132.730 1.00 57.62  ? 462 GLN A CD  1 
ATOM   1815 O OE1 . GLN A 1 462 ? 183.358 134.830 131.958 1.00 60.65  ? 462 GLN A OE1 1 
ATOM   1816 N NE2 . GLN A 1 462 ? 184.023 134.221 134.008 1.00 58.04  ? 462 GLN A NE2 1 
ATOM   1817 N N   . CYS A 1 463 ? 189.568 135.360 132.723 1.00 67.08  ? 463 CYS A N   1 
ATOM   1818 C CA  . CYS A 1 463 ? 190.579 136.056 131.937 1.00 65.19  ? 463 CYS A CA  1 
ATOM   1819 C C   . CYS A 1 463 ? 191.770 135.173 131.600 1.00 68.07  ? 463 CYS A C   1 
ATOM   1820 O O   . CYS A 1 463 ? 192.315 135.274 130.498 1.00 70.18  ? 463 CYS A O   1 
ATOM   1821 C CB  . CYS A 1 463 ? 191.063 137.307 132.675 1.00 64.73  ? 463 CYS A CB  1 
ATOM   1822 S SG  . CYS A 1 463 ? 189.920 138.701 132.602 1.00 69.06  ? 463 CYS A SG  1 
ATOM   1823 N N   . LEU A 1 464 ? 192.192 134.308 132.526 1.00 71.65  ? 464 LEU A N   1 
ATOM   1824 C CA  . LEU A 1 464 ? 193.251 133.356 132.200 1.00 73.69  ? 464 LEU A CA  1 
ATOM   1825 C C   . LEU A 1 464 ? 192.833 132.438 131.057 1.00 77.37  ? 464 LEU A C   1 
ATOM   1826 O O   . LEU A 1 464 ? 193.611 132.195 130.126 1.00 77.02  ? 464 LEU A O   1 
ATOM   1827 C CB  . LEU A 1 464 ? 193.620 132.529 133.429 1.00 72.10  ? 464 LEU A CB  1 
ATOM   1828 C CG  . LEU A 1 464 ? 194.283 133.246 134.598 1.00 67.50  ? 464 LEU A CG  1 
ATOM   1829 C CD1 . LEU A 1 464 ? 194.743 132.221 135.617 1.00 72.11  ? 464 LEU A CD1 1 
ATOM   1830 C CD2 . LEU A 1 464 ? 195.443 134.094 134.115 1.00 63.82  ? 464 LEU A CD2 1 
ATOM   1831 N N   . ARG A 1 465 ? 191.605 131.918 131.112 1.00 77.91  ? 465 ARG A N   1 
ATOM   1832 C CA  . ARG A 1 465 ? 191.087 131.083 130.035 1.00 73.56  ? 465 ARG A CA  1 
ATOM   1833 C C   . ARG A 1 465 ? 190.993 131.854 128.728 1.00 74.83  ? 465 ARG A C   1 
ATOM   1834 O O   . ARG A 1 465 ? 191.301 131.312 127.661 1.00 78.02  ? 465 ARG A O   1 
ATOM   1835 C CB  . ARG A 1 465 ? 189.719 130.530 130.427 1.00 68.40  ? 465 ARG A CB  1 
ATOM   1836 C CG  . ARG A 1 465 ? 188.932 129.925 129.287 1.00 70.62  ? 465 ARG A CG  1 
ATOM   1837 C CD  . ARG A 1 465 ? 189.559 128.643 128.787 1.00 75.49  ? 465 ARG A CD  1 
ATOM   1838 N NE  . ARG A 1 465 ? 188.881 128.146 127.596 1.00 76.34  ? 465 ARG A NE  1 
ATOM   1839 C CZ  . ARG A 1 465 ? 187.790 127.396 127.619 1.00 69.52  ? 465 ARG A CZ  1 
ATOM   1840 N NH1 . ARG A 1 465 ? 187.227 127.033 128.758 1.00 68.62  ? 465 ARG A NH1 1 
ATOM   1841 N NH2 . ARG A 1 465 ? 187.250 127.001 126.470 1.00 68.10  ? 465 ARG A NH2 1 
ATOM   1842 N N   . ARG A 1 466 ? 190.564 133.114 128.790 1.00 76.70  ? 466 ARG A N   1 
ATOM   1843 C CA  . ARG A 1 466 ? 190.503 133.930 127.584 1.00 75.44  ? 466 ARG A CA  1 
ATOM   1844 C C   . ARG A 1 466 ? 191.889 134.116 126.979 1.00 78.40  ? 466 ARG A C   1 
ATOM   1845 O O   . ARG A 1 466 ? 192.055 134.046 125.758 1.00 83.44  ? 466 ARG A O   1 
ATOM   1846 C CB  . ARG A 1 466 ? 189.856 135.280 127.896 1.00 74.29  ? 466 ARG A CB  1 
ATOM   1847 C CG  . ARG A 1 466 ? 188.344 135.226 128.041 1.00 68.32  ? 466 ARG A CG  1 
ATOM   1848 C CD  . ARG A 1 466 ? 187.748 136.617 128.191 1.00 64.11  ? 466 ARG A CD  1 
ATOM   1849 N NE  . ARG A 1 466 ? 188.314 137.559 127.233 1.00 69.62  ? 466 ARG A NE  1 
ATOM   1850 C CZ  . ARG A 1 466 ? 188.001 137.599 125.946 1.00 72.53  ? 466 ARG A CZ  1 
ATOM   1851 N NH1 . ARG A 1 466 ? 187.135 136.751 125.418 1.00 71.78  ? 466 ARG A NH1 1 
ATOM   1852 N NH2 . ARG A 1 466 ? 188.574 138.510 125.167 1.00 73.10  ? 466 ARG A NH2 1 
ATOM   1853 N N   . TYR A 1 467 ? 192.899 134.356 127.819 1.00 77.97  ? 467 TYR A N   1 
ATOM   1854 C CA  . TYR A 1 467 ? 194.266 134.465 127.314 1.00 82.19  ? 467 TYR A CA  1 
ATOM   1855 C C   . TYR A 1 467 ? 194.732 133.156 126.696 1.00 83.18  ? 467 TYR A C   1 
ATOM   1856 O O   . TYR A 1 467 ? 195.404 133.150 125.659 1.00 84.30  ? 467 TYR A O   1 
ATOM   1857 C CB  . TYR A 1 467 ? 195.220 134.874 128.433 1.00 82.15  ? 467 TYR A CB  1 
ATOM   1858 C CG  . TYR A 1 467 ? 196.668 134.591 128.104 1.00 85.57  ? 467 TYR A CG  1 
ATOM   1859 C CD1 . TYR A 1 467 ? 197.354 135.367 127.180 1.00 87.15  ? 467 TYR A CD1 1 
ATOM   1860 C CD2 . TYR A 1 467 ? 197.348 133.545 128.713 1.00 87.11  ? 467 TYR A CD2 1 
ATOM   1861 C CE1 . TYR A 1 467 ? 198.677 135.111 126.874 1.00 91.60  ? 467 TYR A CE1 1 
ATOM   1862 C CE2 . TYR A 1 467 ? 198.670 133.282 128.413 1.00 89.61  ? 467 TYR A CE2 1 
ATOM   1863 C CZ  . TYR A 1 467 ? 199.329 134.068 127.495 1.00 93.63  ? 467 TYR A CZ  1 
ATOM   1864 O OH  . TYR A 1 467 ? 200.646 133.809 127.195 1.00 97.94  ? 467 TYR A OH  1 
ATOM   1865 N N   . ARG A 1 468 ? 194.397 132.037 127.337 1.00 81.53  ? 468 ARG A N   1 
ATOM   1866 C CA  . ARG A 1 468 ? 194.781 130.732 126.814 1.00 82.20  ? 468 ARG A CA  1 
ATOM   1867 C C   . ARG A 1 468 ? 194.163 130.486 125.444 1.00 86.27  ? 468 ARG A C   1 
ATOM   1868 O O   . ARG A 1 468 ? 194.817 129.941 124.548 1.00 87.86  ? 468 ARG A O   1 
ATOM   1869 C CB  . ARG A 1 468 ? 194.361 129.645 127.800 1.00 79.10  ? 468 ARG A CB  1 
ATOM   1870 C CG  . ARG A 1 468 ? 194.689 128.232 127.377 1.00 80.54  ? 468 ARG A CG  1 
ATOM   1871 C CD  . ARG A 1 468 ? 193.981 127.252 128.293 1.00 82.24  ? 468 ARG A CD  1 
ATOM   1872 N NE  . ARG A 1 468 ? 194.091 127.660 129.689 1.00 82.11  ? 468 ARG A NE  1 
ATOM   1873 C CZ  . ARG A 1 468 ? 193.419 127.107 130.689 1.00 79.07  ? 468 ARG A CZ  1 
ATOM   1874 N NH1 . ARG A 1 468 ? 192.569 126.114 130.486 1.00 72.47  ? 468 ARG A NH1 1 
ATOM   1875 N NH2 . ARG A 1 468 ? 193.604 127.563 131.925 1.00 78.22  ? 468 ARG A NH2 1 
ATOM   1876 N N   . ASP A 1 469 ? 192.906 130.882 125.264 1.00 85.37  ? 469 ASP A N   1 
ATOM   1877 C CA  . ASP A 1 469 ? 192.206 130.660 124.007 1.00 83.46  ? 469 ASP A CA  1 
ATOM   1878 C C   . ASP A 1 469 ? 192.447 131.754 122.974 1.00 86.55  ? 469 ASP A C   1 
ATOM   1879 O O   . ASP A 1 469 ? 192.036 131.590 121.821 1.00 87.96  ? 469 ASP A O   1 
ATOM   1880 C CB  . ASP A 1 469 ? 190.701 130.528 124.258 1.00 78.10  ? 469 ASP A CB  1 
ATOM   1881 C CG  . ASP A 1 469 ? 190.352 129.282 125.042 1.00 79.14  ? 469 ASP A CG  1 
ATOM   1882 O OD1 . ASP A 1 469 ? 191.271 128.489 125.335 1.00 79.07  ? 469 ASP A OD1 1 
ATOM   1883 O OD2 . ASP A 1 469 ? 189.161 129.094 125.366 1.00 80.90  ? 469 ASP A OD2 1 
ATOM   1884 N N   . THR A 1 470 ? 193.096 132.858 123.346 1.00 86.91  ? 470 THR A N   1 
ATOM   1885 C CA  . THR A 1 470 ? 193.302 133.969 122.430 1.00 88.27  ? 470 THR A CA  1 
ATOM   1886 C C   . THR A 1 470 ? 194.761 134.303 122.163 1.00 91.35  ? 470 THR A C   1 
ATOM   1887 O O   . THR A 1 470 ? 195.039 134.996 121.178 1.00 96.85  ? 470 THR A O   1 
ATOM   1888 C CB  . THR A 1 470 ? 192.605 135.234 122.954 1.00 88.20  ? 470 THR A CB  1 
ATOM   1889 O OG1 . THR A 1 470 ? 192.998 135.465 124.312 1.00 89.47  ? 470 THR A OG1 1 
ATOM   1890 C CG2 . THR A 1 470 ? 191.095 135.077 122.881 1.00 83.91  ? 470 THR A CG2 1 
ATOM   1891 N N   . LYS A 1 471 ? 195.690 133.843 123.002 1.00 90.28  ? 471 LYS A N   1 
ATOM   1892 C CA  . LYS A 1 471 ? 197.122 134.071 122.804 1.00 97.50  ? 471 LYS A CA  1 
ATOM   1893 C C   . LYS A 1 471 ? 197.451 135.562 122.729 1.00 99.16  ? 471 LYS A C   1 
ATOM   1894 O O   . LYS A 1 471 ? 198.305 135.989 121.949 1.00 98.27  ? 471 LYS A O   1 
ATOM   1895 C CB  . LYS A 1 471 ? 197.629 133.340 121.557 1.00 97.23  ? 471 LYS A CB  1 
ATOM   1896 C CG  . LYS A 1 471 ? 197.289 131.859 121.523 1.00 95.77  ? 471 LYS A CG  1 
ATOM   1897 C CD  . LYS A 1 471 ? 197.952 131.112 122.666 1.00 97.25  ? 471 LYS A CD  1 
ATOM   1898 C CE  . LYS A 1 471 ? 199.465 131.182 122.562 1.00 102.94 ? 471 LYS A CE  1 
ATOM   1899 N NZ  . LYS A 1 471 ? 199.956 130.620 121.274 1.00 107.45 ? 471 LYS A NZ  1 
ATOM   1900 N N   . ARG A 1 472 ? 196.768 136.360 123.546 1.00 97.10  ? 472 ARG A N   1 
ATOM   1901 C CA  . ARG A 1 472 ? 197.018 137.795 123.654 1.00 94.64  ? 472 ARG A CA  1 
ATOM   1902 C C   . ARG A 1 472 ? 197.281 138.115 125.119 1.00 92.86  ? 472 ARG A C   1 
ATOM   1903 O O   . ARG A 1 472 ? 196.368 138.046 125.949 1.00 88.72  ? 472 ARG A O   1 
ATOM   1904 C CB  . ARG A 1 472 ? 195.843 138.604 123.111 1.00 95.38  ? 472 ARG A CB  1 
ATOM   1905 C CG  . ARG A 1 472 ? 195.570 138.377 121.636 1.00 98.52  ? 472 ARG A CG  1 
ATOM   1906 C CD  . ARG A 1 472 ? 194.413 139.231 121.155 1.00 102.34 ? 472 ARG A CD  1 
ATOM   1907 N NE  . ARG A 1 472 ? 194.656 140.651 121.380 1.00 101.91 ? 472 ARG A NE  1 
ATOM   1908 C CZ  . ARG A 1 472 ? 195.271 141.450 120.519 1.00 105.19 ? 472 ARG A CZ  1 
ATOM   1909 N NH1 . ARG A 1 472 ? 195.720 141.001 119.359 1.00 108.64 ? 472 ARG A NH1 1 
ATOM   1910 N NH2 . ARG A 1 472 ? 195.442 142.731 120.832 1.00 107.55 ? 472 ARG A NH2 1 
ATOM   1911 N N   . ALA A 1 473 ? 198.526 138.467 125.435 1.00 94.01  ? 473 ALA A N   1 
ATOM   1912 C CA  . ALA A 1 473 ? 198.922 138.605 126.832 1.00 89.08  ? 473 ALA A CA  1 
ATOM   1913 C C   . ALA A 1 473 ? 198.326 139.852 127.472 1.00 85.51  ? 473 ALA A C   1 
ATOM   1914 O O   . ALA A 1 473 ? 197.840 139.798 128.606 1.00 83.79  ? 473 ALA A O   1 
ATOM   1915 C CB  . ALA A 1 473 ? 200.446 138.623 126.942 1.00 85.24  ? 473 ALA A CB  1 
ATOM   1916 N N   . PHE A 1 474 ? 198.358 140.980 126.772 1.00 83.47  ? 474 PHE A N   1 
ATOM   1917 C CA  . PHE A 1 474 ? 197.993 142.262 127.364 1.00 85.29  ? 474 PHE A CA  1 
ATOM   1918 C C   . PHE A 1 474 ? 196.531 142.312 127.812 1.00 84.49  ? 474 PHE A C   1 
ATOM   1919 O O   . PHE A 1 474 ? 196.266 142.377 129.025 1.00 81.03  ? 474 PHE A O   1 
ATOM   1920 C CB  . PHE A 1 474 ? 198.309 143.394 126.378 1.00 86.72  ? 474 PHE A CB  1 
ATOM   1921 C CG  . PHE A 1 474 ? 197.499 144.641 126.594 1.00 87.02  ? 474 PHE A CG  1 
ATOM   1922 C CD1 . PHE A 1 474 ? 197.699 145.432 127.710 1.00 89.12  ? 474 PHE A CD1 1 
ATOM   1923 C CD2 . PHE A 1 474 ? 196.550 145.032 125.667 1.00 83.74  ? 474 PHE A CD2 1 
ATOM   1924 C CE1 . PHE A 1 474 ? 196.957 146.578 127.907 1.00 86.69  ? 474 PHE A CE1 1 
ATOM   1925 C CE2 . PHE A 1 474 ? 195.808 146.176 125.858 1.00 84.88  ? 474 PHE A CE2 1 
ATOM   1926 C CZ  . PHE A 1 474 ? 196.012 146.950 126.980 1.00 84.60  ? 474 PHE A CZ  1 
ATOM   1927 N N   . PRO A 1 475 ? 195.559 142.243 126.890 1.00 84.22  ? 475 PRO A N   1 
ATOM   1928 C CA  . PRO A 1 475 ? 194.186 142.623 127.258 1.00 81.49  ? 475 PRO A CA  1 
ATOM   1929 C C   . PRO A 1 475 ? 193.568 141.731 128.312 1.00 84.11  ? 475 PRO A C   1 
ATOM   1930 O O   . PRO A 1 475 ? 192.538 142.100 128.887 1.00 86.97  ? 475 PRO A O   1 
ATOM   1931 C CB  . PRO A 1 475 ? 193.419 142.523 125.930 1.00 80.90  ? 475 PRO A CB  1 
ATOM   1932 C CG  . PRO A 1 475 ? 194.452 142.313 124.870 1.00 84.58  ? 475 PRO A CG  1 
ATOM   1933 C CD  . PRO A 1 475 ? 195.590 141.639 125.548 1.00 86.96  ? 475 PRO A CD  1 
ATOM   1934 N N   . HIS A 1 476 ? 194.140 140.553 128.555 1.00 82.68  ? 476 HIS A N   1 
ATOM   1935 C CA  . HIS A 1 476 ? 193.609 139.626 129.546 1.00 80.96  ? 476 HIS A CA  1 
ATOM   1936 C C   . HIS A 1 476 ? 194.475 139.555 130.795 1.00 76.83  ? 476 HIS A C   1 
ATOM   1937 O O   . HIS A 1 476 ? 193.949 139.537 131.912 1.00 71.43  ? 476 HIS A O   1 
ATOM   1938 C CB  . HIS A 1 476 ? 193.468 138.233 128.933 1.00 80.65  ? 476 HIS A CB  1 
ATOM   1939 C CG  . HIS A 1 476 ? 192.850 138.241 127.572 1.00 75.42  ? 476 HIS A CG  1 
ATOM   1940 N ND1 . HIS A 1 476 ? 193.588 138.416 126.422 1.00 79.79  ? 476 HIS A ND1 1 
ATOM   1941 C CD2 . HIS A 1 476 ? 191.562 138.116 127.178 1.00 75.43  ? 476 HIS A CD2 1 
ATOM   1942 C CE1 . HIS A 1 476 ? 192.781 138.388 125.377 1.00 81.59  ? 476 HIS A CE1 1 
ATOM   1943 N NE2 . HIS A 1 476 ? 191.546 138.206 125.808 1.00 79.24  ? 476 HIS A NE2 1 
ATOM   1944 N N   . LEU A 1 477 ? 195.799 139.522 130.632 1.00 79.54  ? 477 LEU A N   1 
ATOM   1945 C CA  . LEU A 1 477 ? 196.682 139.434 131.786 1.00 81.34  ? 477 LEU A CA  1 
ATOM   1946 C C   . LEU A 1 477 ? 196.674 140.714 132.611 1.00 83.93  ? 477 LEU A C   1 
ATOM   1947 O O   . LEU A 1 477 ? 196.839 140.651 133.835 1.00 86.05  ? 477 LEU A O   1 
ATOM   1948 C CB  . LEU A 1 477 ? 198.102 139.098 131.338 1.00 83.68  ? 477 LEU A CB  1 
ATOM   1949 C CG  . LEU A 1 477 ? 198.341 137.635 130.971 1.00 84.05  ? 477 LEU A CG  1 
ATOM   1950 C CD1 . LEU A 1 477 ? 199.783 137.424 130.557 1.00 90.81  ? 477 LEU A CD1 1 
ATOM   1951 C CD2 . LEU A 1 477 ? 197.980 136.734 132.137 1.00 74.06  ? 477 LEU A CD2 1 
ATOM   1952 N N   . VAL A 1 478 ? 196.483 141.879 131.984 1.00 80.11  ? 478 VAL A N   1 
ATOM   1953 C CA  . VAL A 1 478 ? 196.430 143.105 132.776 1.00 76.69  ? 478 VAL A CA  1 
ATOM   1954 C C   . VAL A 1 478 ? 195.252 143.063 133.747 1.00 79.90  ? 478 VAL A C   1 
ATOM   1955 O O   . VAL A 1 478 ? 195.398 143.362 134.937 1.00 78.00  ? 478 VAL A O   1 
ATOM   1956 C CB  . VAL A 1 478 ? 196.377 144.339 131.857 1.00 77.66  ? 478 VAL A CB  1 
ATOM   1957 C CG1 . VAL A 1 478 ? 196.234 145.605 132.680 1.00 74.42  ? 478 VAL A CG1 1 
ATOM   1958 C CG2 . VAL A 1 478 ? 197.633 144.406 131.015 1.00 80.67  ? 478 VAL A CG2 1 
ATOM   1959 N N   . ASN A 1 479 ? 194.076 142.650 133.272 1.00 81.09  ? 479 ASN A N   1 
ATOM   1960 C CA  . ASN A 1 479 ? 192.927 142.550 134.168 1.00 76.53  ? 479 ASN A CA  1 
ATOM   1961 C C   . ASN A 1 479 ? 193.062 141.357 135.105 1.00 78.23  ? 479 ASN A C   1 
ATOM   1962 O O   . ASN A 1 479 ? 192.499 141.354 136.206 1.00 78.04  ? 479 ASN A O   1 
ATOM   1963 C CB  . ASN A 1 479 ? 191.630 142.469 133.367 1.00 74.11  ? 479 ASN A CB  1 
ATOM   1964 C CG  . ASN A 1 479 ? 191.864 142.079 131.935 1.00 77.79  ? 479 ASN A CG  1 
ATOM   1965 O OD1 . ASN A 1 479 ? 192.987 142.152 131.445 1.00 80.15  ? 479 ASN A OD1 1 
ATOM   1966 N ND2 . ASN A 1 479 ? 190.803 141.670 131.246 1.00 77.64  ? 479 ASN A ND2 1 
ATOM   1967 N N   . ALA A 1 480 ? 193.805 140.333 134.692 1.00 78.29  ? 480 ALA A N   1 
ATOM   1968 C CA  . ALA A 1 480 ? 194.100 139.231 135.596 1.00 75.31  ? 480 ALA A CA  1 
ATOM   1969 C C   . ALA A 1 480 ? 194.833 139.778 136.811 1.00 74.46  ? 480 ALA A C   1 
ATOM   1970 O O   . ALA A 1 480 ? 194.495 139.458 137.954 1.00 69.38  ? 480 ALA A O   1 
ATOM   1971 C CB  . ALA A 1 480 ? 194.933 138.164 134.889 1.00 77.73  ? 480 ALA A CB  1 
ATOM   1972 N N   . GLY A 1 481 ? 195.823 140.633 136.560 1.00 75.53  ? 481 GLY A N   1 
ATOM   1973 C CA  . GLY A 1 481 ? 196.487 141.328 137.649 1.00 76.87  ? 481 GLY A CA  1 
ATOM   1974 C C   . GLY A 1 481 ? 195.560 142.263 138.400 1.00 76.58  ? 481 GLY A C   1 
ATOM   1975 O O   . GLY A 1 481 ? 195.694 142.438 139.613 1.00 78.11  ? 481 GLY A O   1 
ATOM   1976 N N   . LYS A 1 482 ? 194.606 142.869 137.691 1.00 76.64  ? 482 LYS A N   1 
ATOM   1977 C CA  . LYS A 1 482 ? 193.637 143.756 138.333 1.00 75.47  ? 482 LYS A CA  1 
ATOM   1978 C C   . LYS A 1 482 ? 192.826 143.020 139.394 1.00 75.50  ? 482 LYS A C   1 
ATOM   1979 O O   . LYS A 1 482 ? 192.606 143.537 140.495 1.00 74.51  ? 482 LYS A O   1 
ATOM   1980 C CB  . LYS A 1 482 ? 192.715 144.359 137.273 1.00 72.86  ? 482 LYS A CB  1 
ATOM   1981 C CG  . LYS A 1 482 ? 191.421 144.937 137.805 1.00 68.78  ? 482 LYS A CG  1 
ATOM   1982 C CD  . LYS A 1 482 ? 190.605 145.528 136.671 1.00 68.73  ? 482 LYS A CD  1 
ATOM   1983 C CE  . LYS A 1 482 ? 189.257 146.010 137.152 1.00 69.91  ? 482 LYS A CE  1 
ATOM   1984 N NZ  . LYS A 1 482 ? 188.449 144.890 137.694 1.00 68.37  ? 482 LYS A NZ  1 
ATOM   1985 N N   . TYR A 1 483 ? 192.364 141.813 139.074 1.00 76.16  ? 483 TYR A N   1 
ATOM   1986 C CA  . TYR A 1 483 ? 191.611 141.029 140.052 1.00 73.57  ? 483 TYR A CA  1 
ATOM   1987 C C   . TYR A 1 483 ? 192.538 140.378 141.076 1.00 77.80  ? 483 TYR A C   1 
ATOM   1988 O O   . TYR A 1 483 ? 192.140 140.133 142.224 1.00 77.53  ? 483 TYR A O   1 
ATOM   1989 C CB  . TYR A 1 483 ? 190.752 139.989 139.340 1.00 67.52  ? 483 TYR A CB  1 
ATOM   1990 C CG  . TYR A 1 483 ? 189.688 140.602 138.461 1.00 61.92  ? 483 TYR A CG  1 
ATOM   1991 C CD1 . TYR A 1 483 ? 188.551 141.174 139.010 1.00 63.91  ? 483 TYR A CD1 1 
ATOM   1992 C CD2 . TYR A 1 483 ? 189.821 140.610 137.085 1.00 61.42  ? 483 TYR A CD2 1 
ATOM   1993 C CE1 . TYR A 1 483 ? 187.583 141.735 138.208 1.00 65.60  ? 483 TYR A CE1 1 
ATOM   1994 C CE2 . TYR A 1 483 ? 188.864 141.171 136.279 1.00 60.58  ? 483 TYR A CE2 1 
ATOM   1995 C CZ  . TYR A 1 483 ? 187.749 141.732 136.843 1.00 63.65  ? 483 TYR A CZ  1 
ATOM   1996 O OH  . TYR A 1 483 ? 186.791 142.284 136.030 1.00 65.74  ? 483 TYR A OH  1 
ATOM   1997 N N   . SER A 1 484 ? 193.783 140.093 140.689 1.00 77.66  ? 484 SER A N   1 
ATOM   1998 C CA  . SER A 1 484 ? 194.756 139.654 141.679 1.00 80.59  ? 484 SER A CA  1 
ATOM   1999 C C   . SER A 1 484 ? 194.993 140.737 142.719 1.00 79.90  ? 484 SER A C   1 
ATOM   2000 O O   . SER A 1 484 ? 195.342 140.440 143.866 1.00 81.67  ? 484 SER A O   1 
ATOM   2001 C CB  . SER A 1 484 ? 196.069 139.272 141.001 1.00 79.77  ? 484 SER A CB  1 
ATOM   2002 O OG  . SER A 1 484 ? 196.787 140.430 140.623 1.00 81.46  ? 484 SER A OG  1 
ATOM   2003 N N   . THR A 1 485 ? 194.819 142.000 142.331 1.00 76.73  ? 485 THR A N   1 
ATOM   2004 C CA  . THR A 1 485 ? 194.897 143.082 143.303 1.00 76.58  ? 485 THR A CA  1 
ATOM   2005 C C   . THR A 1 485 ? 193.796 142.954 144.346 1.00 79.40  ? 485 THR A C   1 
ATOM   2006 O O   . THR A 1 485 ? 194.031 143.191 145.535 1.00 82.62  ? 485 THR A O   1 
ATOM   2007 C CB  . THR A 1 485 ? 194.816 144.433 142.603 1.00 76.67  ? 485 THR A CB  1 
ATOM   2008 O OG1 . THR A 1 485 ? 195.499 144.357 141.347 1.00 79.01  ? 485 THR A OG1 1 
ATOM   2009 C CG2 . THR A 1 485 ? 195.481 145.489 143.454 1.00 81.04  ? 485 THR A CG2 1 
ATOM   2010 N N   . THR A 1 486 ? 192.588 142.578 143.922 1.00 81.23  ? 486 THR A N   1 
ATOM   2011 C CA  . THR A 1 486 ? 191.526 142.290 144.882 1.00 82.52  ? 486 THR A CA  1 
ATOM   2012 C C   . THR A 1 486 ? 191.904 141.117 145.774 1.00 85.03  ? 486 THR A C   1 
ATOM   2013 O O   . THR A 1 486 ? 191.653 141.138 146.987 1.00 82.83  ? 486 THR A O   1 
ATOM   2014 C CB  . THR A 1 486 ? 190.219 141.992 144.149 1.00 78.55  ? 486 THR A CB  1 
ATOM   2015 O OG1 . THR A 1 486 ? 189.761 143.171 143.479 1.00 85.46  ? 486 THR A OG1 1 
ATOM   2016 C CG2 . THR A 1 486 ? 189.155 141.519 145.126 1.00 75.22  ? 486 THR A CG2 1 
ATOM   2017 N N   . PHE A 1 487 ? 192.495 140.076 145.183 1.00 82.76  ? 487 PHE A N   1 
ATOM   2018 C CA  . PHE A 1 487 ? 192.962 138.938 145.972 1.00 78.41  ? 487 PHE A CA  1 
ATOM   2019 C C   . PHE A 1 487 ? 193.905 139.394 147.078 1.00 81.55  ? 487 PHE A C   1 
ATOM   2020 O O   . PHE A 1 487 ? 193.734 139.040 148.251 1.00 80.76  ? 487 PHE A O   1 
ATOM   2021 C CB  . PHE A 1 487 ? 193.671 137.924 145.075 1.00 70.06  ? 487 PHE A CB  1 
ATOM   2022 C CG  . PHE A 1 487 ? 192.776 137.257 144.082 1.00 66.79  ? 487 PHE A CG  1 
ATOM   2023 C CD1 . PHE A 1 487 ? 191.429 137.104 144.335 1.00 73.25  ? 487 PHE A CD1 1 
ATOM   2024 C CD2 . PHE A 1 487 ? 193.290 136.770 142.894 1.00 67.96  ? 487 PHE A CD2 1 
ATOM   2025 C CE1 . PHE A 1 487 ? 190.609 136.485 143.418 1.00 77.14  ? 487 PHE A CE1 1 
ATOM   2026 C CE2 . PHE A 1 487 ? 192.477 136.151 141.973 1.00 67.17  ? 487 PHE A CE2 1 
ATOM   2027 C CZ  . PHE A 1 487 ? 191.136 136.008 142.233 1.00 71.72  ? 487 PHE A CZ  1 
ATOM   2028 N N   . PHE A 1 488 ? 194.910 140.188 146.710 1.00 82.46  ? 488 PHE A N   1 
ATOM   2029 C CA  . PHE A 1 488 ? 195.898 140.653 147.677 1.00 86.58  ? 488 PHE A CA  1 
ATOM   2030 C C   . PHE A 1 488 ? 195.271 141.577 148.710 1.00 90.03  ? 488 PHE A C   1 
ATOM   2031 O O   . PHE A 1 488 ? 195.635 141.536 149.890 1.00 94.50  ? 488 PHE A O   1 
ATOM   2032 C CB  . PHE A 1 488 ? 197.048 141.352 146.954 1.00 85.77  ? 488 PHE A CB  1 
ATOM   2033 C CG  . PHE A 1 488 ? 197.849 140.441 146.075 1.00 84.72  ? 488 PHE A CG  1 
ATOM   2034 C CD1 . PHE A 1 488 ? 198.037 139.116 146.422 1.00 84.31  ? 488 PHE A CD1 1 
ATOM   2035 C CD2 . PHE A 1 488 ? 198.407 140.906 144.899 1.00 81.67  ? 488 PHE A CD2 1 
ATOM   2036 C CE1 . PHE A 1 488 ? 198.770 138.272 145.615 1.00 83.41  ? 488 PHE A CE1 1 
ATOM   2037 C CE2 . PHE A 1 488 ? 199.141 140.067 144.086 1.00 77.71  ? 488 PHE A CE2 1 
ATOM   2038 C CZ  . PHE A 1 488 ? 199.323 138.749 144.444 1.00 81.67  ? 488 PHE A CZ  1 
ATOM   2039 N N   . MET A 1 489 ? 194.335 142.426 148.285 1.00 87.02  ? 489 MET A N   1 
ATOM   2040 C CA  . MET A 1 489 ? 193.647 143.305 149.223 1.00 86.28  ? 489 MET A CA  1 
ATOM   2041 C C   . MET A 1 489 ? 192.913 142.500 150.285 1.00 93.47  ? 489 MET A C   1 
ATOM   2042 O O   . MET A 1 489 ? 193.034 142.777 151.484 1.00 94.47  ? 489 MET A O   1 
ATOM   2043 C CB  . MET A 1 489 ? 192.681 144.214 148.464 1.00 83.03  ? 489 MET A CB  1 
ATOM   2044 C CG  . MET A 1 489 ? 191.429 144.589 149.234 1.00 89.60  ? 489 MET A CG  1 
ATOM   2045 S SD  . MET A 1 489 ? 191.761 145.612 150.673 1.00 89.16  ? 489 MET A SD  1 
ATOM   2046 C CE  . MET A 1 489 ? 192.621 146.962 149.891 1.00 86.94  ? 489 MET A CE  1 
ATOM   2047 N N   . VAL A 1 490 ? 192.163 141.481 149.863 1.00 92.28  ? 490 VAL A N   1 
ATOM   2048 C CA  . VAL A 1 490 ? 191.433 140.659 150.824 1.00 90.49  ? 490 VAL A CA  1 
ATOM   2049 C C   . VAL A 1 490 ? 192.398 139.894 151.721 1.00 96.03  ? 490 VAL A C   1 
ATOM   2050 O O   . VAL A 1 490 ? 192.190 139.792 152.938 1.00 96.92  ? 490 VAL A O   1 
ATOM   2051 C CB  . VAL A 1 490 ? 190.467 139.712 150.093 1.00 88.82  ? 490 VAL A CB  1 
ATOM   2052 C CG1 . VAL A 1 490 ? 189.716 138.854 151.092 1.00 86.10  ? 490 VAL A CG1 1 
ATOM   2053 C CG2 . VAL A 1 490 ? 189.501 140.508 149.240 1.00 84.99  ? 490 VAL A CG2 1 
ATOM   2054 N N   . THR A 1 491 ? 193.466 139.345 151.138 1.00 97.25  ? 491 THR A N   1 
ATOM   2055 C CA  . THR A 1 491 ? 194.430 138.584 151.925 1.00 98.35  ? 491 THR A CA  1 
ATOM   2056 C C   . THR A 1 491 ? 195.061 139.451 153.002 1.00 102.62 ? 491 THR A C   1 
ATOM   2057 O O   . THR A 1 491 ? 195.170 139.041 154.163 1.00 107.19 ? 491 THR A O   1 
ATOM   2058 C CB  . THR A 1 491 ? 195.510 138.007 151.014 1.00 92.05  ? 491 THR A CB  1 
ATOM   2059 O OG1 . THR A 1 491 ? 194.897 137.224 149.985 1.00 90.58  ? 491 THR A OG1 1 
ATOM   2060 C CG2 . THR A 1 491 ? 196.461 137.135 151.812 1.00 93.20  ? 491 THR A CG2 1 
ATOM   2061 N N   . PHE A 1 492 ? 195.469 140.666 152.638 1.00 102.36 ? 492 PHE A N   1 
ATOM   2062 C CA  . PHE A 1 492 ? 196.116 141.538 153.606 1.00 105.71 ? 492 PHE A CA  1 
ATOM   2063 C C   . PHE A 1 492 ? 195.126 142.089 154.619 1.00 106.03 ? 492 PHE A C   1 
ATOM   2064 O O   . PHE A 1 492 ? 195.496 142.307 155.774 1.00 108.58 ? 492 PHE A O   1 
ATOM   2065 C CB  . PHE A 1 492 ? 196.856 142.661 152.885 1.00 105.46 ? 492 PHE A CB  1 
ATOM   2066 C CG  . PHE A 1 492 ? 198.195 142.243 152.364 1.00 105.31 ? 492 PHE A CG  1 
ATOM   2067 C CD1 . PHE A 1 492 ? 198.991 141.388 153.105 1.00 105.92 ? 492 PHE A CD1 1 
ATOM   2068 C CD2 . PHE A 1 492 ? 198.650 142.677 151.135 1.00 101.70 ? 492 PHE A CD2 1 
ATOM   2069 C CE1 . PHE A 1 492 ? 200.219 140.986 152.639 1.00 106.12 ? 492 PHE A CE1 1 
ATOM   2070 C CE2 . PHE A 1 492 ? 199.881 142.273 150.664 1.00 102.23 ? 492 PHE A CE2 1 
ATOM   2071 C CZ  . PHE A 1 492 ? 200.665 141.428 151.416 1.00 106.80 ? 492 PHE A CZ  1 
ATOM   2072 N N   . ALA A 1 493 ? 193.868 142.294 154.226 1.00 102.02 ? 493 ALA A N   1 
ATOM   2073 C CA  . ALA A 1 493 ? 192.856 142.670 155.206 1.00 102.73 ? 493 ALA A CA  1 
ATOM   2074 C C   . ALA A 1 493 ? 192.683 141.577 156.251 1.00 104.73 ? 493 ALA A C   1 
ATOM   2075 O O   . ALA A 1 493 ? 192.651 141.849 157.459 1.00 106.38 ? 493 ALA A O   1 
ATOM   2076 C CB  . ALA A 1 493 ? 191.531 142.960 154.503 1.00 98.76  ? 493 ALA A CB  1 
ATOM   2077 N N   . ALA A 1 494 ? 192.593 140.323 155.802 1.00 105.05 ? 494 ALA A N   1 
ATOM   2078 C CA  . ALA A 1 494 ? 192.451 139.215 156.738 1.00 108.68 ? 494 ALA A CA  1 
ATOM   2079 C C   . ALA A 1 494 ? 193.676 139.086 157.635 1.00 114.40 ? 494 ALA A C   1 
ATOM   2080 O O   . ALA A 1 494 ? 193.548 138.888 158.850 1.00 116.56 ? 494 ALA A O   1 
ATOM   2081 C CB  . ALA A 1 494 ? 192.203 137.914 155.977 1.00 105.07 ? 494 ALA A CB  1 
ATOM   2082 N N   . LEU A 1 495 ? 194.873 139.198 157.053 1.00 114.03 ? 495 LEU A N   1 
ATOM   2083 C CA  . LEU A 1 495 ? 196.092 139.093 157.847 1.00 114.21 ? 495 LEU A CA  1 
ATOM   2084 C C   . LEU A 1 495 ? 196.182 140.216 158.869 1.00 117.59 ? 495 LEU A C   1 
ATOM   2085 O O   . LEU A 1 495 ? 196.564 139.987 160.022 1.00 121.76 ? 495 LEU A O   1 
ATOM   2086 C CB  . LEU A 1 495 ? 197.318 139.099 156.935 1.00 113.32 ? 495 LEU A CB  1 
ATOM   2087 C CG  . LEU A 1 495 ? 197.497 137.874 156.039 1.00 113.06 ? 495 LEU A CG  1 
ATOM   2088 C CD1 . LEU A 1 495 ? 198.757 138.003 155.205 1.00 113.34 ? 495 LEU A CD1 1 
ATOM   2089 C CD2 . LEU A 1 495 ? 197.525 136.599 156.864 1.00 116.35 ? 495 LEU A CD2 1 
ATOM   2090 N N   . TYR A 1 496 ? 195.834 141.438 158.463 1.00 113.92 ? 496 TYR A N   1 
ATOM   2091 C CA  . TYR A 1 496 ? 195.863 142.570 159.377 1.00 117.35 ? 496 TYR A CA  1 
ATOM   2092 C C   . TYR A 1 496 ? 194.881 142.378 160.522 1.00 119.87 ? 496 TYR A C   1 
ATOM   2093 O O   . TYR A 1 496 ? 195.212 142.645 161.682 1.00 120.83 ? 496 TYR A O   1 
ATOM   2094 C CB  . TYR A 1 496 ? 195.564 143.855 158.606 1.00 118.39 ? 496 TYR A CB  1 
ATOM   2095 C CG  . TYR A 1 496 ? 195.170 145.029 159.466 1.00 121.84 ? 496 TYR A CG  1 
ATOM   2096 C CD1 . TYR A 1 496 ? 196.103 145.677 160.260 1.00 123.43 ? 496 TYR A CD1 1 
ATOM   2097 C CD2 . TYR A 1 496 ? 193.866 145.502 159.468 1.00 122.25 ? 496 TYR A CD2 1 
ATOM   2098 C CE1 . TYR A 1 496 ? 195.746 146.754 161.045 1.00 124.47 ? 496 TYR A CE1 1 
ATOM   2099 C CE2 . TYR A 1 496 ? 193.500 146.579 160.246 1.00 123.71 ? 496 TYR A CE2 1 
ATOM   2100 C CZ  . TYR A 1 496 ? 194.442 147.202 161.033 1.00 123.61 ? 496 TYR A CZ  1 
ATOM   2101 O OH  . TYR A 1 496 ? 194.080 148.278 161.811 1.00 121.50 ? 496 TYR A OH  1 
ATOM   2102 N N   . SER A 1 497 ? 193.671 141.902 160.221 1.00 118.13 ? 497 SER A N   1 
ATOM   2103 C CA  . SER A 1 497 ? 192.697 141.661 161.281 1.00 119.01 ? 497 SER A CA  1 
ATOM   2104 C C   . SER A 1 497 ? 193.192 140.592 162.249 1.00 122.93 ? 497 SER A C   1 
ATOM   2105 O O   . SER A 1 497 ? 193.123 140.761 163.474 1.00 126.03 ? 497 SER A O   1 
ATOM   2106 C CB  . SER A 1 497 ? 191.356 141.257 160.675 1.00 116.41 ? 497 SER A CB  1 
ATOM   2107 O OG  . SER A 1 497 ? 190.372 141.097 161.680 1.00 117.07 ? 497 SER A OG  1 
ATOM   2108 N N   . THR A 1 498 ? 193.709 139.484 161.713 1.00 122.62 ? 498 THR A N   1 
ATOM   2109 C CA  . THR A 1 498 ? 194.177 138.402 162.571 1.00 125.86 ? 498 THR A CA  1 
ATOM   2110 C C   . THR A 1 498 ? 195.338 138.853 163.447 1.00 129.26 ? 498 THR A C   1 
ATOM   2111 O O   . THR A 1 498 ? 195.380 138.542 164.643 1.00 132.63 ? 498 THR A O   1 
ATOM   2112 C CB  . THR A 1 498 ? 194.585 137.198 161.724 1.00 122.41 ? 498 THR A CB  1 
ATOM   2113 O OG1 . THR A 1 498 ? 195.450 137.628 160.666 1.00 121.17 ? 498 THR A OG1 1 
ATOM   2114 C CG2 . THR A 1 498 ? 193.357 136.523 161.133 1.00 117.95 ? 498 THR A CG2 1 
ATOM   2115 N N   . HIS A 1 499 ? 196.285 139.596 162.875 1.00 127.67 ? 499 HIS A N   1 
ATOM   2116 C CA  . HIS A 1 499 ? 197.438 140.037 163.649 1.00 129.77 ? 499 HIS A CA  1 
ATOM   2117 C C   . HIS A 1 499 ? 197.060 141.106 164.665 1.00 130.74 ? 499 HIS A C   1 
ATOM   2118 O O   . HIS A 1 499 ? 197.654 141.163 165.748 1.00 131.54 ? 499 HIS A O   1 
ATOM   2119 C CB  . HIS A 1 499 ? 198.533 140.541 162.712 1.00 130.57 ? 499 HIS A CB  1 
ATOM   2120 C CG  . HIS A 1 499 ? 199.099 139.478 161.824 1.00 129.29 ? 499 HIS A CG  1 
ATOM   2121 N ND1 . HIS A 1 499 ? 199.941 139.758 160.769 1.00 126.29 ? 499 HIS A ND1 1 
ATOM   2122 C CD2 . HIS A 1 499 ? 198.945 138.133 161.835 1.00 128.51 ? 499 HIS A CD2 1 
ATOM   2123 C CE1 . HIS A 1 499 ? 200.279 138.631 160.168 1.00 126.64 ? 499 HIS A CE1 1 
ATOM   2124 N NE2 . HIS A 1 499 ? 199.688 137.630 160.795 1.00 128.68 ? 499 HIS A NE2 1 
ATOM   2125 N N   . LYS A 1 500 ? 196.087 141.961 164.342 1.00 126.99 ? 500 LYS A N   1 
ATOM   2126 C CA  . LYS A 1 500 ? 195.607 142.923 165.325 1.00 126.91 ? 500 LYS A CA  1 
ATOM   2127 C C   . LYS A 1 500 ? 194.930 142.215 166.488 1.00 130.09 ? 500 LYS A C   1 
ATOM   2128 O O   . LYS A 1 500 ? 195.072 142.630 167.644 1.00 130.64 ? 500 LYS A O   1 
ATOM   2129 C CB  . LYS A 1 500 ? 194.654 143.919 164.669 1.00 122.36 ? 500 LYS A CB  1 
ATOM   2130 C CG  . LYS A 1 500 ? 194.817 145.343 165.169 1.00 121.12 ? 500 LYS A CG  1 
ATOM   2131 C CD  . LYS A 1 500 ? 193.635 146.206 164.773 1.00 121.72 ? 500 LYS A CD  1 
ATOM   2132 C CE  . LYS A 1 500 ? 192.379 145.775 165.508 1.00 118.99 ? 500 LYS A CE  1 
ATOM   2133 N NZ  . LYS A 1 500 ? 192.529 145.916 166.982 1.00 116.06 ? 500 LYS A NZ  1 
ATOM   2134 N N   . GLU A 1 501 ? 194.185 141.145 166.200 1.00 131.65 ? 501 GLU A N   1 
ATOM   2135 C CA  . GLU A 1 501 ? 193.643 140.324 167.278 1.00 135.02 ? 501 GLU A CA  1 
ATOM   2136 C C   . GLU A 1 501 ? 194.761 139.691 168.096 1.00 135.01 ? 501 GLU A C   1 
ATOM   2137 O O   . GLU A 1 501 ? 194.678 139.620 169.328 1.00 136.43 ? 501 GLU A O   1 
ATOM   2138 C CB  . GLU A 1 501 ? 192.713 139.251 166.711 1.00 134.53 ? 501 GLU A CB  1 
ATOM   2139 C CG  . GLU A 1 501 ? 191.440 139.801 166.086 1.00 134.34 ? 501 GLU A CG  1 
ATOM   2140 C CD  . GLU A 1 501 ? 190.533 140.478 167.098 1.00 136.36 ? 501 GLU A CD  1 
ATOM   2141 O OE1 . GLU A 1 501 ? 190.632 140.158 168.301 1.00 134.32 ? 501 GLU A OE1 1 
ATOM   2142 O OE2 . GLU A 1 501 ? 189.718 141.331 166.688 1.00 136.99 ? 501 GLU A OE2 1 
ATOM   2143 N N   . ARG A 1 502 ? 195.819 139.227 167.427 1.00 134.39 ? 502 ARG A N   1 
ATOM   2144 C CA  . ARG A 1 502 ? 196.973 138.689 168.135 1.00 136.12 ? 502 ARG A CA  1 
ATOM   2145 C C   . ARG A 1 502 ? 197.778 139.775 168.837 1.00 138.74 ? 502 ARG A C   1 
ATOM   2146 O O   . ARG A 1 502 ? 198.470 139.479 169.816 1.00 140.93 ? 502 ARG A O   1 
ATOM   2147 C CB  . ARG A 1 502 ? 197.869 137.915 167.168 1.00 138.35 ? 502 ARG A CB  1 
ATOM   2148 C CG  . ARG A 1 502 ? 197.194 136.704 166.545 1.00 138.48 ? 502 ARG A CG  1 
ATOM   2149 C CD  . ARG A 1 502 ? 198.073 136.058 165.488 1.00 137.95 ? 502 ARG A CD  1 
ATOM   2150 N NE  . ARG A 1 502 ? 199.325 135.562 166.046 1.00 142.27 ? 502 ARG A NE  1 
ATOM   2151 C CZ  . ARG A 1 502 ? 200.270 134.955 165.342 1.00 141.62 ? 502 ARG A CZ  1 
ATOM   2152 N NH1 . ARG A 1 502 ? 200.138 134.749 164.041 1.00 139.03 ? 502 ARG A NH1 1 
ATOM   2153 N NH2 . ARG A 1 502 ? 201.375 134.544 165.957 1.00 140.65 ? 502 ARG A NH2 1 
ATOM   2154 N N   . GLY A 1 503 ? 197.709 141.016 168.359 1.00 137.67 ? 503 GLY A N   1 
ATOM   2155 C CA  . GLY A 1 503 ? 198.367 142.126 169.018 1.00 139.30 ? 503 GLY A CA  1 
ATOM   2156 C C   . GLY A 1 503 ? 199.834 142.307 168.703 1.00 143.74 ? 503 GLY A C   1 
ATOM   2157 O O   . GLY A 1 503 ? 200.495 143.111 169.369 1.00 146.73 ? 503 GLY A O   1 
ATOM   2158 N N   . HIS A 1 504 ? 200.368 141.593 167.716 1.00 144.11 ? 504 HIS A N   1 
ATOM   2159 C CA  . HIS A 1 504 ? 201.774 141.740 167.366 1.00 141.57 ? 504 HIS A CA  1 
ATOM   2160 C C   . HIS A 1 504 ? 202.039 143.114 166.760 1.00 141.48 ? 504 HIS A C   1 
ATOM   2161 O O   . HIS A 1 504 ? 201.169 143.719 166.129 1.00 142.01 ? 504 HIS A O   1 
ATOM   2162 C CB  . HIS A 1 504 ? 202.197 140.647 166.386 1.00 139.81 ? 504 HIS A CB  1 
ATOM   2163 C CG  . HIS A 1 504 ? 202.167 139.270 166.970 1.00 140.87 ? 504 HIS A CG  1 
ATOM   2164 N ND1 . HIS A 1 504 ? 202.057 139.038 168.324 1.00 140.89 ? 504 HIS A ND1 1 
ATOM   2165 C CD2 . HIS A 1 504 ? 202.232 138.051 166.383 1.00 141.04 ? 504 HIS A CD2 1 
ATOM   2166 C CE1 . HIS A 1 504 ? 202.057 137.736 168.547 1.00 140.28 ? 504 HIS A CE1 1 
ATOM   2167 N NE2 . HIS A 1 504 ? 202.162 137.115 167.386 1.00 140.23 ? 504 HIS A NE2 1 
ATOM   2168 N N   . SER A 1 505 ? 203.262 143.610 166.963 1.00 142.31 ? 505 SER A N   1 
ATOM   2169 C CA  . SER A 1 505 ? 203.633 144.905 166.400 1.00 144.70 ? 505 SER A CA  1 
ATOM   2170 C C   . SER A 1 505 ? 203.652 144.865 164.879 1.00 144.43 ? 505 SER A C   1 
ATOM   2171 O O   . SER A 1 505 ? 203.281 145.851 164.227 1.00 142.22 ? 505 SER A O   1 
ATOM   2172 C CB  . SER A 1 505 ? 204.995 145.344 166.936 1.00 141.47 ? 505 SER A CB  1 
ATOM   2173 O OG  . SER A 1 505 ? 206.016 144.451 166.528 1.00 140.92 ? 505 SER A OG  1 
ATOM   2174 N N   . ASP A 1 506 ? 204.045 143.727 164.299 1.00 144.81 ? 506 ASP A N   1 
ATOM   2175 C CA  . ASP A 1 506 ? 204.108 143.593 162.849 1.00 142.58 ? 506 ASP A CA  1 
ATOM   2176 C C   . ASP A 1 506 ? 202.768 143.880 162.190 1.00 137.02 ? 506 ASP A C   1 
ATOM   2177 O O   . ASP A 1 506 ? 202.730 144.164 160.987 1.00 134.94 ? 506 ASP A O   1 
ATOM   2178 C CB  . ASP A 1 506 ? 204.586 142.190 162.476 1.00 143.36 ? 506 ASP A CB  1 
ATOM   2179 C CG  . ASP A 1 506 ? 203.845 141.102 163.229 1.00 140.33 ? 506 ASP A CG  1 
ATOM   2180 O OD1 . ASP A 1 506 ? 202.632 140.924 162.987 1.00 137.13 ? 506 ASP A OD1 1 
ATOM   2181 O OD2 . ASP A 1 506 ? 204.477 140.422 164.064 1.00 137.93 ? 506 ASP A OD2 1 
ATOM   2182 N N   . THR A 1 507 ? 201.675 143.818 162.956 1.00 134.55 ? 507 THR A N   1 
ATOM   2183 C CA  . THR A 1 507 ? 200.363 144.198 162.452 1.00 133.30 ? 507 THR A CA  1 
ATOM   2184 C C   . THR A 1 507 ? 200.417 145.549 161.759 1.00 131.88 ? 507 THR A C   1 
ATOM   2185 O O   . THR A 1 507 ? 199.888 145.715 160.654 1.00 130.79 ? 507 THR A O   1 
ATOM   2186 C CB  . THR A 1 507 ? 199.355 144.245 163.602 1.00 133.84 ? 507 THR A CB  1 
ATOM   2187 O OG1 . THR A 1 507 ? 199.420 143.027 164.352 1.00 135.47 ? 507 THR A OG1 1 
ATOM   2188 C CG2 . THR A 1 507 ? 197.951 144.441 163.066 1.00 133.10 ? 507 THR A CG2 1 
ATOM   2189 N N   . MET A 1 508 ? 201.076 146.522 162.393 1.00 131.78 ? 508 MET A N   1 
ATOM   2190 C CA  . MET A 1 508 ? 201.153 147.857 161.810 1.00 132.50 ? 508 MET A CA  1 
ATOM   2191 C C   . MET A 1 508 ? 201.749 147.800 160.411 1.00 132.49 ? 508 MET A C   1 
ATOM   2192 O O   . MET A 1 508 ? 201.249 148.445 159.482 1.00 127.56 ? 508 MET A O   1 
ATOM   2193 C CB  . MET A 1 508 ? 201.971 148.779 162.713 1.00 133.13 ? 508 MET A CB  1 
ATOM   2194 C CG  . MET A 1 508 ? 202.124 150.190 162.172 1.00 135.31 ? 508 MET A CG  1 
ATOM   2195 S SD  . MET A 1 508 ? 200.545 150.954 161.756 1.00 142.36 ? 508 MET A SD  1 
ATOM   2196 C CE  . MET A 1 508 ? 199.720 150.931 163.345 1.00 138.59 ? 508 MET A CE  1 
ATOM   2197 N N   . VAL A 1 509 ? 202.798 146.992 160.236 1.00 134.76 ? 509 VAL A N   1 
ATOM   2198 C CA  . VAL A 1 509 ? 203.384 146.817 158.911 1.00 133.10 ? 509 VAL A CA  1 
ATOM   2199 C C   . VAL A 1 509 ? 202.322 146.335 157.934 1.00 128.80 ? 509 VAL A C   1 
ATOM   2200 O O   . VAL A 1 509 ? 202.111 146.933 156.871 1.00 125.53 ? 509 VAL A O   1 
ATOM   2201 C CB  . VAL A 1 509 ? 204.572 145.841 158.977 1.00 132.85 ? 509 VAL A CB  1 
ATOM   2202 C CG1 . VAL A 1 509 ? 205.193 145.664 157.600 1.00 132.40 ? 509 VAL A CG1 1 
ATOM   2203 C CG2 . VAL A 1 509 ? 205.603 146.327 159.984 1.00 129.06 ? 509 VAL A CG2 1 
ATOM   2204 N N   . PHE A 1 510 ? 201.596 145.279 158.310 1.00 129.00 ? 510 PHE A N   1 
ATOM   2205 C CA  . PHE A 1 510 ? 200.528 144.782 157.452 1.00 125.82 ? 510 PHE A CA  1 
ATOM   2206 C C   . PHE A 1 510 ? 199.476 145.854 157.216 1.00 124.27 ? 510 PHE A C   1 
ATOM   2207 O O   . PHE A 1 510 ? 198.894 145.929 156.127 1.00 119.08 ? 510 PHE A O   1 
ATOM   2208 C CB  . PHE A 1 510 ? 199.901 143.530 158.059 1.00 126.42 ? 510 PHE A CB  1 
ATOM   2209 C CG  . PHE A 1 510 ? 200.673 142.276 157.781 1.00 125.81 ? 510 PHE A CG  1 
ATOM   2210 C CD1 . PHE A 1 510 ? 200.449 141.555 156.622 1.00 122.83 ? 510 PHE A CD1 1 
ATOM   2211 C CD2 . PHE A 1 510 ? 201.625 141.820 158.674 1.00 128.75 ? 510 PHE A CD2 1 
ATOM   2212 C CE1 . PHE A 1 510 ? 201.157 140.401 156.359 1.00 123.08 ? 510 PHE A CE1 1 
ATOM   2213 C CE2 . PHE A 1 510 ? 202.337 140.666 158.417 1.00 130.08 ? 510 PHE A CE2 1 
ATOM   2214 C CZ  . PHE A 1 510 ? 202.102 139.956 157.258 1.00 127.18 ? 510 PHE A CZ  1 
ATOM   2215 N N   . PHE A 1 511 ? 199.232 146.707 158.215 1.00 125.80 ? 511 PHE A N   1 
ATOM   2216 C CA  . PHE A 1 511 ? 198.302 147.811 158.018 1.00 124.00 ? 511 PHE A CA  1 
ATOM   2217 C C   . PHE A 1 511 ? 198.757 148.681 156.857 1.00 121.50 ? 511 PHE A C   1 
ATOM   2218 O O   . PHE A 1 511 ? 197.972 148.996 155.955 1.00 119.11 ? 511 PHE A O   1 
ATOM   2219 C CB  . PHE A 1 511 ? 198.173 148.636 159.298 1.00 127.49 ? 511 PHE A CB  1 
ATOM   2220 C CG  . PHE A 1 511 ? 197.181 149.761 159.196 1.00 125.84 ? 511 PHE A CG  1 
ATOM   2221 C CD1 . PHE A 1 511 ? 195.826 149.499 159.084 1.00 120.78 ? 511 PHE A CD1 1 
ATOM   2222 C CD2 . PHE A 1 511 ? 197.602 151.078 159.219 1.00 126.70 ? 511 PHE A CD2 1 
ATOM   2223 C CE1 . PHE A 1 511 ? 194.911 150.528 158.991 1.00 120.39 ? 511 PHE A CE1 1 
ATOM   2224 C CE2 . PHE A 1 511 ? 196.689 152.112 159.130 1.00 127.31 ? 511 PHE A CE2 1 
ATOM   2225 C CZ  . PHE A 1 511 ? 195.342 151.836 159.013 1.00 123.06 ? 511 PHE A CZ  1 
ATOM   2226 N N   . TYR A 1 512 ? 200.043 149.036 156.839 1.00 121.45 ? 512 TYR A N   1 
ATOM   2227 C CA  . TYR A 1 512 ? 200.581 149.728 155.676 1.00 122.57 ? 512 TYR A CA  1 
ATOM   2228 C C   . TYR A 1 512 ? 200.414 148.873 154.429 1.00 119.27 ? 512 TYR A C   1 
ATOM   2229 O O   . TYR A 1 512 ? 199.962 149.358 153.385 1.00 113.15 ? 512 TYR A O   1 
ATOM   2230 C CB  . TYR A 1 512 ? 202.050 150.084 155.903 1.00 124.78 ? 512 TYR A CB  1 
ATOM   2231 C CG  . TYR A 1 512 ? 202.255 151.426 156.566 1.00 127.78 ? 512 TYR A CG  1 
ATOM   2232 C CD1 . TYR A 1 512 ? 202.127 152.604 155.841 1.00 128.28 ? 512 TYR A CD1 1 
ATOM   2233 C CD2 . TYR A 1 512 ? 202.583 151.517 157.911 1.00 132.47 ? 512 TYR A CD2 1 
ATOM   2234 C CE1 . TYR A 1 512 ? 202.315 153.835 156.437 1.00 131.58 ? 512 TYR A CE1 1 
ATOM   2235 C CE2 . TYR A 1 512 ? 202.774 152.747 158.517 1.00 134.62 ? 512 TYR A CE2 1 
ATOM   2236 C CZ  . TYR A 1 512 ? 202.639 153.902 157.775 1.00 134.26 ? 512 TYR A CZ  1 
ATOM   2237 O OH  . TYR A 1 512 ? 202.828 155.127 158.372 1.00 133.05 ? 512 TYR A OH  1 
ATOM   2238 N N   . LEU A 1 513 ? 200.710 147.576 154.544 1.00 118.03 ? 513 LEU A N   1 
ATOM   2239 C CA  . LEU A 1 513 ? 200.525 146.660 153.429 1.00 111.32 ? 513 LEU A CA  1 
ATOM   2240 C C   . LEU A 1 513 ? 199.085 146.616 152.952 1.00 107.27 ? 513 LEU A C   1 
ATOM   2241 O O   . LEU A 1 513 ? 198.842 146.227 151.806 1.00 106.78 ? 513 LEU A O   1 
ATOM   2242 C CB  . LEU A 1 513 ? 200.983 145.256 153.820 1.00 110.23 ? 513 LEU A CB  1 
ATOM   2243 C CG  . LEU A 1 513 ? 202.492 145.017 153.819 1.00 112.34 ? 513 LEU A CG  1 
ATOM   2244 C CD1 . LEU A 1 513 ? 202.813 143.658 154.413 1.00 113.58 ? 513 LEU A CD1 1 
ATOM   2245 C CD2 . LEU A 1 513 ? 203.041 145.127 152.407 1.00 107.76 ? 513 LEU A CD2 1 
ATOM   2246 N N   . TRP A 1 514 ? 198.126 147.004 153.791 1.00 106.58 ? 514 TRP A N   1 
ATOM   2247 C CA  . TRP A 1 514 ? 196.761 147.148 153.307 1.00 100.96 ? 514 TRP A CA  1 
ATOM   2248 C C   . TRP A 1 514 ? 196.607 148.446 152.525 1.00 99.32  ? 514 TRP A C   1 
ATOM   2249 O O   . TRP A 1 514 ? 196.148 148.442 151.376 1.00 98.62  ? 514 TRP A O   1 
ATOM   2250 C CB  . TRP A 1 514 ? 195.779 147.099 154.478 1.00 101.37 ? 514 TRP A CB  1 
ATOM   2251 C CG  . TRP A 1 514 ? 194.351 147.169 154.059 1.00 91.61  ? 514 TRP A CG  1 
ATOM   2252 C CD1 . TRP A 1 514 ? 193.566 146.131 153.665 1.00 90.68  ? 514 TRP A CD1 1 
ATOM   2253 C CD2 . TRP A 1 514 ? 193.531 148.341 153.994 1.00 89.87  ? 514 TRP A CD2 1 
ATOM   2254 N NE1 . TRP A 1 514 ? 192.307 146.581 153.357 1.00 92.99  ? 514 TRP A NE1 1 
ATOM   2255 C CE2 . TRP A 1 514 ? 192.260 147.935 153.551 1.00 90.98  ? 514 TRP A CE2 1 
ATOM   2256 C CE3 . TRP A 1 514 ? 193.749 149.693 154.266 1.00 90.36  ? 514 TRP A CE3 1 
ATOM   2257 C CZ2 . TRP A 1 514 ? 191.211 148.831 153.374 1.00 87.91  ? 514 TRP A CZ2 1 
ATOM   2258 C CZ3 . TRP A 1 514 ? 192.706 150.580 154.089 1.00 88.15  ? 514 TRP A CZ3 1 
ATOM   2259 C CH2 . TRP A 1 514 ? 191.454 150.146 153.648 1.00 86.42  ? 514 TRP A CH2 1 
ATOM   2260 N N   . ILE A 1 515 ? 197.042 149.561 153.120 1.00 100.28 ? 515 ILE A N   1 
ATOM   2261 C CA  . ILE A 1 515 ? 196.741 150.875 152.559 1.00 100.91 ? 515 ILE A CA  1 
ATOM   2262 C C   . ILE A 1 515 ? 197.282 150.990 151.145 1.00 99.55  ? 515 ILE A C   1 
ATOM   2263 O O   . ILE A 1 515 ? 196.569 151.415 150.226 1.00 95.59  ? 515 ILE A O   1 
ATOM   2264 C CB  . ILE A 1 515 ? 197.302 151.986 153.462 1.00 101.55 ? 515 ILE A CB  1 
ATOM   2265 C CG1 . ILE A 1 515 ? 196.757 151.855 154.882 1.00 103.73 ? 515 ILE A CG1 1 
ATOM   2266 C CG2 . ILE A 1 515 ? 196.965 153.350 152.886 1.00 99.37  ? 515 ILE A CG2 1 
ATOM   2267 C CD1 . ILE A 1 515 ? 197.299 152.897 155.825 1.00 108.59 ? 515 ILE A CD1 1 
ATOM   2268 N N   . VAL A 1 516 ? 198.537 150.585 150.941 1.00 100.23 ? 516 VAL A N   1 
ATOM   2269 C CA  . VAL A 1 516 ? 199.140 150.676 149.616 1.00 99.01  ? 516 VAL A CA  1 
ATOM   2270 C C   . VAL A 1 516 ? 198.285 149.934 148.600 1.00 95.55  ? 516 VAL A C   1 
ATOM   2271 O O   . VAL A 1 516 ? 198.002 150.444 147.509 1.00 94.38  ? 516 VAL A O   1 
ATOM   2272 C CB  . VAL A 1 516 ? 200.586 150.149 149.642 1.00 98.07  ? 516 VAL A CB  1 
ATOM   2273 C CG1 . VAL A 1 516 ? 200.666 148.811 150.361 1.00 97.39  ? 516 VAL A CG1 1 
ATOM   2274 C CG2 . VAL A 1 516 ? 201.128 150.027 148.228 1.00 96.41  ? 516 VAL A CG2 1 
ATOM   2275 N N   . PHE A 1 517 ? 197.826 148.733 148.955 1.00 94.52  ? 517 PHE A N   1 
ATOM   2276 C CA  . PHE A 1 517 ? 196.981 147.999 148.024 1.00 90.12  ? 517 PHE A CA  1 
ATOM   2277 C C   . PHE A 1 517 ? 195.649 148.705 147.826 1.00 87.41  ? 517 PHE A C   1 
ATOM   2278 O O   . PHE A 1 517 ? 195.175 148.831 146.689 1.00 84.23  ? 517 PHE A O   1 
ATOM   2279 C CB  . PHE A 1 517 ? 196.808 146.558 148.487 1.00 86.41  ? 517 PHE A CB  1 
ATOM   2280 C CG  . PHE A 1 517 ? 197.895 145.657 147.991 1.00 87.66  ? 517 PHE A CG  1 
ATOM   2281 C CD1 . PHE A 1 517 ? 197.868 145.177 146.695 1.00 84.81  ? 517 PHE A CD1 1 
ATOM   2282 C CD2 . PHE A 1 517 ? 198.969 145.332 148.795 1.00 94.24  ? 517 PHE A CD2 1 
ATOM   2283 C CE1 . PHE A 1 517 ? 198.876 144.367 146.220 1.00 89.97  ? 517 PHE A CE1 1 
ATOM   2284 C CE2 . PHE A 1 517 ? 199.981 144.524 148.323 1.00 97.25  ? 517 PHE A CE2 1 
ATOM   2285 C CZ  . PHE A 1 517 ? 199.933 144.038 147.036 1.00 98.12  ? 517 PHE A CZ  1 
ATOM   2286 N N   . TYR A 1 518 ? 195.074 149.249 148.904 1.00 90.05  ? 518 TYR A N   1 
ATOM   2287 C CA  . TYR A 1 518 ? 193.869 150.052 148.751 1.00 87.04  ? 518 TYR A CA  1 
ATOM   2288 C C   . TYR A 1 518 ? 194.094 151.202 147.792 1.00 86.53  ? 518 TYR A C   1 
ATOM   2289 O O   . TYR A 1 518 ? 193.137 151.677 147.175 1.00 85.09  ? 518 TYR A O   1 
ATOM   2290 C CB  . TYR A 1 518 ? 193.398 150.594 150.101 1.00 87.02  ? 518 TYR A CB  1 
ATOM   2291 C CG  . TYR A 1 518 ? 192.132 151.420 150.013 1.00 85.19  ? 518 TYR A CG  1 
ATOM   2292 C CD1 . TYR A 1 518 ? 190.886 150.819 150.091 1.00 85.73  ? 518 TYR A CD1 1 
ATOM   2293 C CD2 . TYR A 1 518 ? 192.183 152.798 149.854 1.00 86.94  ? 518 TYR A CD2 1 
ATOM   2294 C CE1 . TYR A 1 518 ? 189.729 151.564 150.012 1.00 83.95  ? 518 TYR A CE1 1 
ATOM   2295 C CE2 . TYR A 1 518 ? 191.029 153.550 149.771 1.00 84.66  ? 518 TYR A CE2 1 
ATOM   2296 C CZ  . TYR A 1 518 ? 189.805 152.926 149.852 1.00 82.89  ? 518 TYR A CZ  1 
ATOM   2297 O OH  . TYR A 1 518 ? 188.648 153.665 149.774 1.00 79.10  ? 518 TYR A OH  1 
ATOM   2298 N N   . ILE A 1 519 ? 195.336 151.654 147.645 1.00 86.18  ? 519 ILE A N   1 
ATOM   2299 C CA  . ILE A 1 519 ? 195.643 152.621 146.602 1.00 87.74  ? 519 ILE A CA  1 
ATOM   2300 C C   . ILE A 1 519 ? 195.603 151.947 145.236 1.00 87.40  ? 519 ILE A C   1 
ATOM   2301 O O   . ILE A 1 519 ? 194.769 152.281 144.385 1.00 84.82  ? 519 ILE A O   1 
ATOM   2302 C CB  . ILE A 1 519 ? 197.004 153.285 146.866 1.00 92.00  ? 519 ILE A CB  1 
ATOM   2303 C CG1 . ILE A 1 519 ? 196.953 154.083 148.166 1.00 92.89  ? 519 ILE A CG1 1 
ATOM   2304 C CG2 . ILE A 1 519 ? 197.391 154.181 145.704 1.00 92.76  ? 519 ILE A CG2 1 
ATOM   2305 C CD1 . ILE A 1 519 ? 195.876 155.144 148.182 1.00 86.60  ? 519 ILE A CD1 1 
ATOM   2306 N N   . ILE A 1 520 ? 196.467 150.949 145.029 1.00 88.42  ? 520 ILE A N   1 
ATOM   2307 C CA  . ILE A 1 520 ? 196.710 150.463 143.672 1.00 84.77  ? 520 ILE A CA  1 
ATOM   2308 C C   . ILE A 1 520 ? 195.443 149.852 143.092 1.00 84.29  ? 520 ILE A C   1 
ATOM   2309 O O   . ILE A 1 520 ? 195.059 150.147 141.955 1.00 81.14  ? 520 ILE A O   1 
ATOM   2310 C CB  . ILE A 1 520 ? 197.893 149.476 143.642 1.00 79.79  ? 520 ILE A CB  1 
ATOM   2311 C CG1 . ILE A 1 520 ? 198.069 148.899 142.238 1.00 75.32  ? 520 ILE A CG1 1 
ATOM   2312 C CG2 . ILE A 1 520 ? 197.714 148.363 144.647 1.00 84.41  ? 520 ILE A CG2 1 
ATOM   2313 C CD1 . ILE A 1 520 ? 199.287 148.021 142.093 1.00 74.16  ? 520 ILE A CD1 1 
ATOM   2314 N N   . SER A 1 521 ? 194.751 149.029 143.882 1.00 84.89  ? 521 SER A N   1 
ATOM   2315 C CA  . SER A 1 521 ? 193.462 148.503 143.450 1.00 80.54  ? 521 SER A CA  1 
ATOM   2316 C C   . SER A 1 521 ? 192.526 149.634 143.061 1.00 79.47  ? 521 SER A C   1 
ATOM   2317 O O   . SER A 1 521 ? 192.002 149.666 141.941 1.00 77.03  ? 521 SER A O   1 
ATOM   2318 C CB  . SER A 1 521 ? 192.843 147.653 144.559 1.00 79.24  ? 521 SER A CB  1 
ATOM   2319 O OG  . SER A 1 521 ? 191.560 147.187 144.182 1.00 81.41  ? 521 SER A OG  1 
ATOM   2320 N N   . SER A 1 522 ? 192.363 150.616 143.951 1.00 82.20  ? 522 SER A N   1 
ATOM   2321 C CA  . SER A 1 522 ? 191.461 151.724 143.672 1.00 81.04  ? 522 SER A CA  1 
ATOM   2322 C C   . SER A 1 522 ? 191.914 152.540 142.478 1.00 81.47  ? 522 SER A C   1 
ATOM   2323 O O   . SER A 1 522 ? 191.130 153.343 141.966 1.00 83.12  ? 522 SER A O   1 
ATOM   2324 C CB  . SER A 1 522 ? 191.329 152.625 144.895 1.00 82.48  ? 522 SER A CB  1 
ATOM   2325 O OG  . SER A 1 522 ? 190.839 151.900 146.007 1.00 79.57  ? 522 SER A OG  1 
ATOM   2326 N N   . CYS A 1 523 ? 193.159 152.373 142.041 1.00 80.75  ? 523 CYS A N   1 
ATOM   2327 C CA  . CYS A 1 523 ? 193.604 152.896 140.760 1.00 80.93  ? 523 CYS A CA  1 
ATOM   2328 C C   . CYS A 1 523 ? 193.555 151.843 139.664 1.00 79.56  ? 523 CYS A C   1 
ATOM   2329 O O   . CYS A 1 523 ? 193.110 152.136 138.550 1.00 77.60  ? 523 CYS A O   1 
ATOM   2330 C CB  . CYS A 1 523 ? 195.025 153.452 140.880 1.00 82.07  ? 523 CYS A CB  1 
ATOM   2331 S SG  . CYS A 1 523 ? 195.226 154.669 142.200 1.00 89.08  ? 523 CYS A SG  1 
ATOM   2332 N N   . TYR A 1 524 ? 193.979 150.613 139.969 1.00 78.87  ? 524 TYR A N   1 
ATOM   2333 C CA  . TYR A 1 524 ? 193.989 149.558 138.962 1.00 77.87  ? 524 TYR A CA  1 
ATOM   2334 C C   . TYR A 1 524 ? 192.584 149.241 138.481 1.00 77.53  ? 524 TYR A C   1 
ATOM   2335 O O   . TYR A 1 524 ? 192.361 149.085 137.276 1.00 76.79  ? 524 TYR A O   1 
ATOM   2336 C CB  . TYR A 1 524 ? 194.652 148.303 139.529 1.00 74.45  ? 524 TYR A CB  1 
ATOM   2337 C CG  . TYR A 1 524 ? 195.264 147.382 138.500 1.00 70.59  ? 524 TYR A CG  1 
ATOM   2338 C CD1 . TYR A 1 524 ? 195.012 147.547 137.147 1.00 69.31  ? 524 TYR A CD1 1 
ATOM   2339 C CD2 . TYR A 1 524 ? 196.096 146.343 138.888 1.00 67.85  ? 524 TYR A CD2 1 
ATOM   2340 C CE1 . TYR A 1 524 ? 195.569 146.705 136.213 1.00 69.16  ? 524 TYR A CE1 1 
ATOM   2341 C CE2 . TYR A 1 524 ? 196.657 145.499 137.963 1.00 68.12  ? 524 TYR A CE2 1 
ATOM   2342 C CZ  . TYR A 1 524 ? 196.391 145.683 136.627 1.00 71.33  ? 524 TYR A CZ  1 
ATOM   2343 O OH  . TYR A 1 524 ? 196.950 144.839 135.698 1.00 77.80  ? 524 TYR A OH  1 
ATOM   2344 N N   . THR A 1 525 ? 191.627 149.151 139.397 1.00 76.28  ? 525 THR A N   1 
ATOM   2345 C CA  . THR A 1 525 ? 190.237 148.981 139.008 1.00 68.81  ? 525 THR A CA  1 
ATOM   2346 C C   . THR A 1 525 ? 189.637 150.257 138.444 1.00 70.03  ? 525 THR A C   1 
ATOM   2347 O O   . THR A 1 525 ? 188.582 150.204 137.807 1.00 75.24  ? 525 THR A O   1 
ATOM   2348 C CB  . THR A 1 525 ? 189.405 148.510 140.201 1.00 71.38  ? 525 THR A CB  1 
ATOM   2349 O OG1 . THR A 1 525 ? 189.560 149.434 141.285 1.00 75.49  ? 525 THR A OG1 1 
ATOM   2350 C CG2 . THR A 1 525 ? 189.857 147.133 140.652 1.00 74.41  ? 525 THR A CG2 1 
ATOM   2351 N N   . LEU A 1 526 ? 190.285 151.402 138.661 1.00 71.11  ? 526 LEU A N   1 
ATOM   2352 C CA  . LEU A 1 526 ? 189.744 152.662 138.166 1.00 72.53  ? 526 LEU A CA  1 
ATOM   2353 C C   . LEU A 1 526 ? 190.261 152.966 136.769 1.00 77.12  ? 526 LEU A C   1 
ATOM   2354 O O   . LEU A 1 526 ? 189.479 153.132 135.826 1.00 76.97  ? 526 LEU A O   1 
ATOM   2355 C CB  . LEU A 1 526 ? 190.095 153.796 139.126 1.00 71.90  ? 526 LEU A CB  1 
ATOM   2356 C CG  . LEU A 1 526 ? 189.442 155.155 138.886 1.00 68.93  ? 526 LEU A CG  1 
ATOM   2357 C CD1 . LEU A 1 526 ? 187.948 155.059 139.092 1.00 72.30  ? 526 LEU A CD1 1 
ATOM   2358 C CD2 . LEU A 1 526 ? 190.038 156.201 139.808 1.00 70.06  ? 526 LEU A CD2 1 
ATOM   2359 N N   . ILE A 1 527 ? 191.585 153.040 136.617 1.00 77.45  ? 527 ILE A N   1 
ATOM   2360 C CA  . ILE A 1 527 ? 192.172 153.416 135.334 1.00 76.69  ? 527 ILE A CA  1 
ATOM   2361 C C   . ILE A 1 527 ? 191.748 152.436 134.250 1.00 75.09  ? 527 ILE A C   1 
ATOM   2362 O O   . ILE A 1 527 ? 191.253 152.831 133.187 1.00 72.84  ? 527 ILE A O   1 
ATOM   2363 C CB  . ILE A 1 527 ? 193.704 153.494 135.451 1.00 74.29  ? 527 ILE A CB  1 
ATOM   2364 C CG1 . ILE A 1 527 ? 194.102 154.494 136.537 1.00 75.48  ? 527 ILE A CG1 1 
ATOM   2365 C CG2 . ILE A 1 527 ? 194.315 153.871 134.118 1.00 74.75  ? 527 ILE A CG2 1 
ATOM   2366 C CD1 . ILE A 1 527 ? 193.628 155.902 136.268 1.00 79.92  ? 527 ILE A CD1 1 
ATOM   2367 N N   . TRP A 1 528 ? 191.903 151.139 134.523 1.00 80.19  ? 528 TRP A N   1 
ATOM   2368 C CA  . TRP A 1 528 ? 191.501 150.115 133.567 1.00 76.26  ? 528 TRP A CA  1 
ATOM   2369 C C   . TRP A 1 528 ? 190.020 150.213 133.245 1.00 73.72  ? 528 TRP A C   1 
ATOM   2370 O O   . TRP A 1 528 ? 189.589 149.803 132.163 1.00 74.55  ? 528 TRP A O   1 
ATOM   2371 C CB  . TRP A 1 528 ? 191.831 148.733 134.125 1.00 74.25  ? 528 TRP A CB  1 
ATOM   2372 C CG  . TRP A 1 528 ? 191.792 147.633 133.125 1.00 71.45  ? 528 TRP A CG  1 
ATOM   2373 C CD1 . TRP A 1 528 ? 192.826 147.190 132.360 1.00 77.47  ? 528 TRP A CD1 1 
ATOM   2374 C CD2 . TRP A 1 528 ? 190.669 146.814 132.796 1.00 73.68  ? 528 TRP A CD2 1 
ATOM   2375 N NE1 . TRP A 1 528 ? 192.415 146.152 131.563 1.00 81.08  ? 528 TRP A NE1 1 
ATOM   2376 C CE2 . TRP A 1 528 ? 191.093 145.901 131.815 1.00 79.62  ? 528 TRP A CE2 1 
ATOM   2377 C CE3 . TRP A 1 528 ? 189.345 146.765 133.234 1.00 76.25  ? 528 TRP A CE3 1 
ATOM   2378 C CZ2 . TRP A 1 528 ? 190.240 144.953 131.263 1.00 82.80  ? 528 TRP A CZ2 1 
ATOM   2379 C CZ3 . TRP A 1 528 ? 188.501 145.823 132.687 1.00 76.76  ? 528 TRP A CZ3 1 
ATOM   2380 C CH2 . TRP A 1 528 ? 188.950 144.930 131.712 1.00 81.48  ? 528 TRP A CH2 1 
ATOM   2381 N N   . ASP A 1 529 ? 189.228 150.747 134.174 1.00 73.94  ? 529 ASP A N   1 
ATOM   2382 C CA  . ASP A 1 529 ? 187.808 150.930 133.909 1.00 72.92  ? 529 ASP A CA  1 
ATOM   2383 C C   . ASP A 1 529 ? 187.554 152.158 133.045 1.00 77.58  ? 529 ASP A C   1 
ATOM   2384 O O   . ASP A 1 529 ? 186.636 152.160 132.218 1.00 79.15  ? 529 ASP A O   1 
ATOM   2385 C CB  . ASP A 1 529 ? 187.037 151.038 135.217 1.00 70.55  ? 529 ASP A CB  1 
ATOM   2386 C CG  . ASP A 1 529 ? 185.550 150.956 135.010 1.00 71.73  ? 529 ASP A CG  1 
ATOM   2387 O OD1 . ASP A 1 529 ? 185.126 150.419 133.966 1.00 65.77  ? 529 ASP A OD1 1 
ATOM   2388 O OD2 . ASP A 1 529 ? 184.804 151.438 135.884 1.00 79.03  ? 529 ASP A OD2 1 
ATOM   2389 N N   . LEU A 1 530 ? 188.346 153.215 133.224 1.00 78.51  ? 530 LEU A N   1 
ATOM   2390 C CA  . LEU A 1 530 ? 188.091 154.465 132.520 1.00 71.92  ? 530 LEU A CA  1 
ATOM   2391 C C   . LEU A 1 530 ? 188.791 154.552 131.175 1.00 73.22  ? 530 LEU A C   1 
ATOM   2392 O O   . LEU A 1 530 ? 188.396 155.373 130.341 1.00 73.07  ? 530 LEU A O   1 
ATOM   2393 C CB  . LEU A 1 530 ? 188.520 155.660 133.376 1.00 72.10  ? 530 LEU A CB  1 
ATOM   2394 C CG  . LEU A 1 530 ? 187.518 156.245 134.373 1.00 73.78  ? 530 LEU A CG  1 
ATOM   2395 C CD1 . LEU A 1 530 ? 187.167 155.256 135.467 1.00 71.03  ? 530 LEU A CD1 1 
ATOM   2396 C CD2 . LEU A 1 530 ? 188.065 157.524 134.977 1.00 81.81  ? 530 LEU A CD2 1 
ATOM   2397 N N   . LYS A 1 531 ? 189.808 153.727 130.938 1.00 77.72  ? 531 LYS A N   1 
ATOM   2398 C CA  . LYS A 1 531 ? 190.606 153.836 129.722 1.00 77.95  ? 531 LYS A CA  1 
ATOM   2399 C C   . LYS A 1 531 ? 190.180 152.818 128.666 1.00 78.29  ? 531 LYS A C   1 
ATOM   2400 O O   . LYS A 1 531 ? 189.937 153.180 127.511 1.00 79.62  ? 531 LYS A O   1 
ATOM   2401 C CB  . LYS A 1 531 ? 192.092 153.675 130.054 1.00 75.30  ? 531 LYS A CB  1 
ATOM   2402 C CG  . LYS A 1 531 ? 192.995 153.835 128.852 1.00 73.74  ? 531 LYS A CG  1 
ATOM   2403 C CD  . LYS A 1 531 ? 192.847 155.217 128.252 1.00 77.54  ? 531 LYS A CD  1 
ATOM   2404 C CE  . LYS A 1 531 ? 193.344 155.248 126.821 1.00 84.22  ? 531 LYS A CE  1 
ATOM   2405 N NZ  . LYS A 1 531 ? 192.496 154.408 125.932 1.00 85.47  ? 531 LYS A NZ  1 
ATOM   2406 N N   . MET A 1 532 ? 190.094 151.541 129.045 1.00 76.69  ? 532 MET A N   1 
ATOM   2407 C CA  . MET A 1 532 ? 189.790 150.486 128.090 1.00 77.76  ? 532 MET A CA  1 
ATOM   2408 C C   . MET A 1 532 ? 188.523 149.703 128.399 1.00 75.29  ? 532 MET A C   1 
ATOM   2409 O O   . MET A 1 532 ? 188.124 148.874 127.574 1.00 81.03  ? 532 MET A O   1 
ATOM   2410 C CB  . MET A 1 532 ? 190.966 149.503 127.981 1.00 79.61  ? 532 MET A CB  1 
ATOM   2411 C CG  . MET A 1 532 ? 191.189 148.650 129.209 1.00 74.04  ? 532 MET A CG  1 
ATOM   2412 S SD  . MET A 1 532 ? 192.735 147.738 129.097 1.00 94.58  ? 532 MET A SD  1 
ATOM   2413 C CE  . MET A 1 532 ? 193.917 149.069 129.288 1.00 83.17  ? 532 MET A CE  1 
ATOM   2414 N N   . ASP A 1 533 ? 187.886 149.920 129.547 1.00 71.94  ? 533 ASP A N   1 
ATOM   2415 C CA  . ASP A 1 533 ? 186.594 149.302 129.819 1.00 70.43  ? 533 ASP A CA  1 
ATOM   2416 C C   . ASP A 1 533 ? 185.454 150.144 129.257 1.00 67.87  ? 533 ASP A C   1 
ATOM   2417 O O   . ASP A 1 533 ? 184.598 149.632 128.530 1.00 63.64  ? 533 ASP A O   1 
ATOM   2418 C CB  . ASP A 1 533 ? 186.415 149.097 131.323 1.00 71.17  ? 533 ASP A CB  1 
ATOM   2419 C CG  . ASP A 1 533 ? 185.440 147.992 131.651 1.00 72.26  ? 533 ASP A CG  1 
ATOM   2420 O OD1 . ASP A 1 533 ? 184.993 147.299 130.716 1.00 72.74  ? 533 ASP A OD1 1 
ATOM   2421 O OD2 . ASP A 1 533 ? 185.125 147.810 132.846 1.00 67.22  ? 533 ASP A OD2 1 
ATOM   2422 N N   . TRP A 1 534 ? 185.437 151.436 129.581 1.00 70.14  ? 534 TRP A N   1 
ATOM   2423 C CA  . TRP A 1 534 ? 184.498 152.379 128.989 1.00 60.88  ? 534 TRP A CA  1 
ATOM   2424 C C   . TRP A 1 534 ? 184.989 152.925 127.655 1.00 68.82  ? 534 TRP A C   1 
ATOM   2425 O O   . TRP A 1 534 ? 184.183 153.177 126.756 1.00 70.86  ? 534 TRP A O   1 
ATOM   2426 C CB  . TRP A 1 534 ? 184.242 153.541 129.949 1.00 58.06  ? 534 TRP A CB  1 
ATOM   2427 C CG  . TRP A 1 534 ? 183.516 153.154 131.178 1.00 57.05  ? 534 TRP A CG  1 
ATOM   2428 C CD1 . TRP A 1 534 ? 182.981 151.939 131.458 1.00 60.47  ? 534 TRP A CD1 1 
ATOM   2429 C CD2 . TRP A 1 534 ? 183.235 153.989 132.304 1.00 59.82  ? 534 TRP A CD2 1 
ATOM   2430 N NE1 . TRP A 1 534 ? 182.383 151.960 132.691 1.00 62.36  ? 534 TRP A NE1 1 
ATOM   2431 C CE2 . TRP A 1 534 ? 182.527 153.209 133.232 1.00 60.26  ? 534 TRP A CE2 1 
ATOM   2432 C CE3 . TRP A 1 534 ? 183.516 155.319 132.618 1.00 63.07  ? 534 TRP A CE3 1 
ATOM   2433 C CZ2 . TRP A 1 534 ? 182.094 153.713 134.452 1.00 58.05  ? 534 TRP A CZ2 1 
ATOM   2434 C CZ3 . TRP A 1 534 ? 183.085 155.817 133.830 1.00 64.39  ? 534 TRP A CZ3 1 
ATOM   2435 C CH2 . TRP A 1 534 ? 182.383 155.016 134.732 1.00 60.95  ? 534 TRP A CH2 1 
ATOM   2436 N N   . GLY A 1 535 ? 186.297 153.120 127.509 1.00 74.24  ? 535 GLY A N   1 
ATOM   2437 C CA  . GLY A 1 535 ? 186.837 153.708 126.301 1.00 76.26  ? 535 GLY A CA  1 
ATOM   2438 C C   . GLY A 1 535 ? 186.852 155.221 126.348 1.00 75.68  ? 535 GLY A C   1 
ATOM   2439 O O   . GLY A 1 535 ? 186.508 155.885 125.367 1.00 81.25  ? 535 GLY A O   1 
ATOM   2440 N N   . LEU A 1 536 ? 187.236 155.774 127.489 1.00 74.05  ? 536 LEU A N   1 
ATOM   2441 C CA  . LEU A 1 536 ? 187.297 157.212 127.694 1.00 83.05  ? 536 LEU A CA  1 
ATOM   2442 C C   . LEU A 1 536 ? 188.750 157.654 127.847 1.00 91.98  ? 536 LEU A C   1 
ATOM   2443 O O   . LEU A 1 536 ? 189.680 156.845 127.787 1.00 90.93  ? 536 LEU A O   1 
ATOM   2444 C CB  . LEU A 1 536 ? 186.463 157.612 128.910 1.00 83.23  ? 536 LEU A CB  1 
ATOM   2445 C CG  . LEU A 1 536 ? 185.002 157.177 128.839 1.00 79.30  ? 536 LEU A CG  1 
ATOM   2446 C CD1 . LEU A 1 536 ? 184.207 157.767 129.987 1.00 78.22  ? 536 LEU A CD1 1 
ATOM   2447 C CD2 . LEU A 1 536 ? 184.400 157.568 127.504 1.00 80.23  ? 536 LEU A CD2 1 
ATOM   2448 N N   . PHE A 1 537 ? 188.936 158.961 128.037 1.00 91.89  ? 537 PHE A N   1 
ATOM   2449 C CA  . PHE A 1 537 ? 190.254 159.581 128.133 1.00 85.15  ? 537 PHE A CA  1 
ATOM   2450 C C   . PHE A 1 537 ? 191.096 159.337 126.890 1.00 92.02  ? 537 PHE A C   1 
ATOM   2451 O O   . PHE A 1 537 ? 192.325 159.418 126.945 1.00 97.00  ? 537 PHE A O   1 
ATOM   2452 C CB  . PHE A 1 537 ? 191.012 159.101 129.374 1.00 83.02  ? 537 PHE A CB  1 
ATOM   2453 C CG  . PHE A 1 537 ? 190.529 159.710 130.654 1.00 87.10  ? 537 PHE A CG  1 
ATOM   2454 C CD1 . PHE A 1 537 ? 189.695 160.810 130.643 1.00 88.30  ? 537 PHE A CD1 1 
ATOM   2455 C CD2 . PHE A 1 537 ? 190.923 159.187 131.872 1.00 89.02  ? 537 PHE A CD2 1 
ATOM   2456 C CE1 . PHE A 1 537 ? 189.258 161.373 131.825 1.00 88.84  ? 537 PHE A CE1 1 
ATOM   2457 C CE2 . PHE A 1 537 ? 190.489 159.746 133.054 1.00 90.92  ? 537 PHE A CE2 1 
ATOM   2458 C CZ  . PHE A 1 537 ? 189.655 160.840 133.031 1.00 88.86  ? 537 PHE A CZ  1 
ATOM   2459 N N   . ASP A 1 538 ? 190.455 159.037 125.766 1.00 94.82  ? 538 ASP A N   1 
ATOM   2460 C CA  . ASP A 1 538 ? 191.186 158.752 124.543 1.00 105.90 ? 538 ASP A CA  1 
ATOM   2461 C C   . ASP A 1 538 ? 191.878 160.010 124.037 1.00 113.92 ? 538 ASP A C   1 
ATOM   2462 O O   . ASP A 1 538 ? 191.315 161.108 124.075 1.00 111.63 ? 538 ASP A O   1 
ATOM   2463 C CB  . ASP A 1 538 ? 190.234 158.199 123.482 1.00 106.79 ? 538 ASP A CB  1 
ATOM   2464 C CG  . ASP A 1 538 ? 190.961 157.616 122.283 1.00 116.28 ? 538 ASP A CG  1 
ATOM   2465 O OD1 . ASP A 1 538 ? 191.793 158.321 121.673 1.00 117.72 ? 538 ASP A OD1 1 
ATOM   2466 O OD2 . ASP A 1 538 ? 190.698 156.442 121.948 1.00 114.65 ? 538 ASP A OD2 1 
ATOM   2467 N N   . LYS A 1 539 ? 193.116 159.843 123.563 1.00 117.62 ? 539 LYS A N   1 
ATOM   2468 C CA  . LYS A 1 539 ? 193.852 160.973 123.005 1.00 118.69 ? 539 LYS A CA  1 
ATOM   2469 C C   . LYS A 1 539 ? 193.147 161.533 121.778 1.00 122.11 ? 539 LYS A C   1 
ATOM   2470 O O   . LYS A 1 539 ? 193.098 162.752 121.582 1.00 124.67 ? 539 LYS A O   1 
ATOM   2471 C CB  . LYS A 1 539 ? 195.280 160.554 122.657 1.00 119.99 ? 539 LYS A CB  1 
ATOM   2472 C CG  . LYS A 1 539 ? 196.125 160.152 123.854 1.00 119.17 ? 539 LYS A CG  1 
ATOM   2473 C CD  . LYS A 1 539 ? 197.530 159.760 123.428 1.00 118.13 ? 539 LYS A CD  1 
ATOM   2474 C CE  . LYS A 1 539 ? 198.381 159.372 124.624 1.00 112.46 ? 539 LYS A CE  1 
ATOM   2475 N NZ  . LYS A 1 539 ? 199.763 158.990 124.222 1.00 107.93 ? 539 LYS A NZ  1 
ATOM   2476 N N   . ASN A 1 540 ? 192.598 160.656 120.938 1.00 120.32 ? 540 ASN A N   1 
ATOM   2477 C CA  . ASN A 1 540 ? 191.843 161.077 119.761 1.00 120.72 ? 540 ASN A CA  1 
ATOM   2478 C C   . ASN A 1 540 ? 190.401 161.408 120.155 1.00 120.07 ? 540 ASN A C   1 
ATOM   2479 O O   . ASN A 1 540 ? 189.432 160.826 119.668 1.00 117.71 ? 540 ASN A O   1 
ATOM   2480 C CB  . ASN A 1 540 ? 191.901 159.995 118.691 1.00 122.71 ? 540 ASN A CB  1 
ATOM   2481 C CG  . ASN A 1 540 ? 191.420 160.483 117.342 1.00 129.60 ? 540 ASN A CG  1 
ATOM   2482 O OD1 . ASN A 1 540 ? 191.425 161.681 117.064 1.00 134.51 ? 540 ASN A OD1 1 
ATOM   2483 N ND2 . ASN A 1 540 ? 191.001 159.552 116.493 1.00 127.08 ? 540 ASN A ND2 1 
ATOM   2484 N N   . ALA A 1 541 ? 190.276 162.373 121.069 1.00 117.98 ? 541 ALA A N   1 
ATOM   2485 C CA  . ALA A 1 541 ? 188.970 162.784 121.568 1.00 116.64 ? 541 ALA A CA  1 
ATOM   2486 C C   . ALA A 1 541 ? 188.235 163.714 120.613 1.00 118.94 ? 541 ALA A C   1 
ATOM   2487 O O   . ALA A 1 541 ? 187.034 163.940 120.797 1.00 117.25 ? 541 ALA A O   1 
ATOM   2488 C CB  . ALA A 1 541 ? 189.116 163.464 122.930 1.00 114.12 ? 541 ALA A CB  1 
ATOM   2489 N N   . GLY A 1 542 ? 188.921 164.247 119.606 1.00 122.05 ? 542 GLY A N   1 
ATOM   2490 C CA  . GLY A 1 542 ? 188.268 165.132 118.654 1.00 123.44 ? 542 GLY A CA  1 
ATOM   2491 C C   . GLY A 1 542 ? 187.735 166.379 119.329 1.00 125.94 ? 542 GLY A C   1 
ATOM   2492 O O   . GLY A 1 542 ? 188.403 166.995 120.167 1.00 126.53 ? 542 GLY A O   1 
ATOM   2493 N N   . GLU A 1 543 ? 186.511 166.763 118.963 1.00 126.35 ? 543 GLU A N   1 
ATOM   2494 C CA  . GLU A 1 543 ? 185.886 167.934 119.566 1.00 126.22 ? 543 GLU A CA  1 
ATOM   2495 C C   . GLU A 1 543 ? 185.506 167.701 121.022 1.00 126.31 ? 543 GLU A C   1 
ATOM   2496 O O   . GLU A 1 543 ? 185.385 168.667 121.781 1.00 126.88 ? 543 GLU A O   1 
ATOM   2497 C CB  . GLU A 1 543 ? 184.648 168.345 118.765 1.00 125.48 ? 543 GLU A CB  1 
ATOM   2498 C CG  . GLU A 1 543 ? 183.450 167.415 118.925 1.00 125.95 ? 543 GLU A CG  1 
ATOM   2499 C CD  . GLU A 1 543 ? 183.665 166.050 118.296 1.00 127.46 ? 543 GLU A CD  1 
ATOM   2500 O OE1 . GLU A 1 543 ? 184.547 165.928 117.420 1.00 130.04 ? 543 GLU A OE1 1 
ATOM   2501 O OE2 . GLU A 1 543 ? 182.955 165.096 118.681 1.00 123.52 ? 543 GLU A OE2 1 
ATOM   2502 N N   . ASN A 1 544 ? 185.320 166.448 121.426 1.00 123.57 ? 544 ASN A N   1 
ATOM   2503 C CA  . ASN A 1 544 ? 184.956 166.139 122.797 1.00 118.60 ? 544 ASN A CA  1 
ATOM   2504 C C   . ASN A 1 544 ? 186.184 166.212 123.701 1.00 115.36 ? 544 ASN A C   1 
ATOM   2505 O O   . ASN A 1 544 ? 187.327 166.295 123.243 1.00 114.11 ? 544 ASN A O   1 
ATOM   2506 C CB  . ASN A 1 544 ? 184.312 164.757 122.882 1.00 114.25 ? 544 ASN A CB  1 
ATOM   2507 C CG  . ASN A 1 544 ? 183.145 164.598 121.925 1.00 119.31 ? 544 ASN A CG  1 
ATOM   2508 O OD1 . ASN A 1 544 ? 182.014 164.975 122.236 1.00 119.26 ? 544 ASN A OD1 1 
ATOM   2509 N ND2 . ASN A 1 544 ? 183.413 164.033 120.752 1.00 118.44 ? 544 ASN A ND2 1 
ATOM   2510 N N   . THR A 1 545 ? 185.934 166.185 125.005 1.00 114.22 ? 545 THR A N   1 
ATOM   2511 C CA  . THR A 1 545 ? 186.987 166.213 126.009 1.00 112.67 ? 545 THR A CA  1 
ATOM   2512 C C   . THR A 1 545 ? 186.835 165.007 126.922 1.00 108.00 ? 545 THR A C   1 
ATOM   2513 O O   . THR A 1 545 ? 185.738 164.743 127.425 1.00 108.33 ? 545 THR A O   1 
ATOM   2514 C CB  . THR A 1 545 ? 186.936 167.503 126.829 1.00 112.12 ? 545 THR A CB  1 
ATOM   2515 O OG1 . THR A 1 545 ? 187.114 168.628 125.961 1.00 120.08 ? 545 THR A OG1 1 
ATOM   2516 C CG2 . THR A 1 545 ? 188.029 167.503 127.886 1.00 108.62 ? 545 THR A CG2 1 
ATOM   2517 N N   . PHE A 1 546 ? 187.933 164.279 127.122 1.00 105.21 ? 546 PHE A N   1 
ATOM   2518 C CA  . PHE A 1 546 ? 188.016 163.113 128.000 1.00 101.86 ? 546 PHE A CA  1 
ATOM   2519 C C   . PHE A 1 546 ? 187.148 161.953 127.530 1.00 99.39  ? 546 PHE A C   1 
ATOM   2520 O O   . PHE A 1 546 ? 186.964 160.984 128.275 1.00 96.12  ? 546 PHE A O   1 
ATOM   2521 C CB  . PHE A 1 546 ? 187.654 163.471 129.449 1.00 103.08 ? 546 PHE A CB  1 
ATOM   2522 C CG  . PHE A 1 546 ? 188.442 164.622 130.005 1.00 107.59 ? 546 PHE A CG  1 
ATOM   2523 C CD1 . PHE A 1 546 ? 189.763 164.818 129.637 1.00 110.45 ? 546 PHE A CD1 1 
ATOM   2524 C CD2 . PHE A 1 546 ? 187.860 165.511 130.890 1.00 105.83 ? 546 PHE A CD2 1 
ATOM   2525 C CE1 . PHE A 1 546 ? 190.487 165.876 130.146 1.00 111.23 ? 546 PHE A CE1 1 
ATOM   2526 C CE2 . PHE A 1 546 ? 188.579 166.571 131.401 1.00 104.20 ? 546 PHE A CE2 1 
ATOM   2527 C CZ  . PHE A 1 546 ? 189.894 166.753 131.029 1.00 107.51 ? 546 PHE A CZ  1 
ATOM   2528 N N   . LEU A 1 547 ? 186.615 162.019 126.316 1.00 102.59 ? 547 LEU A N   1 
ATOM   2529 C CA  . LEU A 1 547 ? 185.715 161.011 125.775 1.00 93.38  ? 547 LEU A CA  1 
ATOM   2530 C C   . LEU A 1 547 ? 186.212 160.580 124.397 1.00 96.89  ? 547 LEU A C   1 
ATOM   2531 O O   . LEU A 1 547 ? 187.323 160.915 123.981 1.00 105.39 ? 547 LEU A O   1 
ATOM   2532 C CB  . LEU A 1 547 ? 184.285 161.551 125.716 1.00 93.75  ? 547 LEU A CB  1 
ATOM   2533 C CG  . LEU A 1 547 ? 183.747 162.174 127.006 1.00 95.79  ? 547 LEU A CG  1 
ATOM   2534 C CD1 . LEU A 1 547 ? 182.359 162.750 126.794 1.00 96.39  ? 547 LEU A CD1 1 
ATOM   2535 C CD2 . LEU A 1 547 ? 183.736 161.157 128.129 1.00 89.27  ? 547 LEU A CD2 1 
ATOM   2536 N N   . ARG A 1 548 ? 185.382 159.826 123.689 1.00 93.11  ? 548 ARG A N   1 
ATOM   2537 C CA  . ARG A 1 548 ? 185.697 159.368 122.346 1.00 97.38  ? 548 ARG A CA  1 
ATOM   2538 C C   . ARG A 1 548 ? 184.914 160.180 121.322 1.00 97.93  ? 548 ARG A C   1 
ATOM   2539 O O   . ARG A 1 548 ? 184.060 161.003 121.662 1.00 95.17  ? 548 ARG A O   1 
ATOM   2540 C CB  . ARG A 1 548 ? 185.394 157.873 122.196 1.00 95.22  ? 548 ARG A CB  1 
ATOM   2541 C CG  . ARG A 1 548 ? 183.936 157.565 121.930 1.00 93.27  ? 548 ARG A CG  1 
ATOM   2542 C CD  . ARG A 1 548 ? 183.644 156.092 122.111 1.00 88.15  ? 548 ARG A CD  1 
ATOM   2543 N NE  . ARG A 1 548 ? 183.595 155.732 123.522 1.00 82.26  ? 548 ARG A NE  1 
ATOM   2544 C CZ  . ARG A 1 548 ? 182.520 155.861 124.284 1.00 83.42  ? 548 ARG A CZ  1 
ATOM   2545 N NH1 . ARG A 1 548 ? 181.383 156.332 123.801 1.00 86.12  ? 548 ARG A NH1 1 
ATOM   2546 N NH2 . ARG A 1 548 ? 182.586 155.509 125.565 1.00 81.78  ? 548 ARG A NH2 1 
ATOM   2547 N N   . GLU A 1 549 ? 185.218 159.936 120.047 1.00 100.00 ? 549 GLU A N   1 
ATOM   2548 C CA  . GLU A 1 549 ? 184.608 160.692 118.961 1.00 102.54 ? 549 GLU A CA  1 
ATOM   2549 C C   . GLU A 1 549 ? 183.227 160.184 118.564 1.00 101.01 ? 549 GLU A C   1 
ATOM   2550 O O   . GLU A 1 549 ? 182.517 160.888 117.838 1.00 99.91  ? 549 GLU A O   1 
ATOM   2551 C CB  . GLU A 1 549 ? 185.536 160.686 117.743 1.00 102.79 ? 549 GLU A CB  1 
ATOM   2552 C CG  . GLU A 1 549 ? 186.082 159.316 117.380 1.00 102.33 ? 549 GLU A CG  1 
ATOM   2553 C CD  . GLU A 1 549 ? 185.108 158.498 116.561 1.00 102.00 ? 549 GLU A CD  1 
ATOM   2554 O OE1 . GLU A 1 549 ? 184.263 159.101 115.867 1.00 99.14  ? 549 GLU A OE1 1 
ATOM   2555 O OE2 . GLU A 1 549 ? 185.186 157.253 116.613 1.00 103.36 ? 549 GLU A OE2 1 
ATOM   2556 N N   . GLU A 1 550 ? 182.827 158.995 119.011 1.00 101.27 ? 550 GLU A N   1 
ATOM   2557 C CA  . GLU A 1 550 ? 181.503 158.442 118.728 1.00 98.11  ? 550 GLU A CA  1 
ATOM   2558 C C   . GLU A 1 550 ? 180.703 158.431 120.025 1.00 92.80  ? 550 GLU A C   1 
ATOM   2559 O O   . GLU A 1 550 ? 180.912 157.575 120.888 1.00 90.82  ? 550 GLU A O   1 
ATOM   2560 C CB  . GLU A 1 550 ? 181.602 157.042 118.132 1.00 96.94  ? 550 GLU A CB  1 
ATOM   2561 C CG  . GLU A 1 550 ? 181.958 157.018 116.661 1.00 100.56 ? 550 GLU A CG  1 
ATOM   2562 C CD  . GLU A 1 550 ? 182.064 155.611 116.117 1.00 103.80 ? 550 GLU A CD  1 
ATOM   2563 O OE1 . GLU A 1 550 ? 181.810 154.658 116.883 1.00 102.94 ? 550 GLU A OE1 1 
ATOM   2564 O OE2 . GLU A 1 550 ? 182.401 155.457 114.926 1.00 105.64 ? 550 GLU A OE2 1 
ATOM   2565 N N   . ILE A 1 551 ? 179.783 159.380 120.155 1.00 92.17  ? 551 ILE A N   1 
ATOM   2566 C CA  . ILE A 1 551 ? 178.942 159.515 121.336 1.00 89.88  ? 551 ILE A CA  1 
ATOM   2567 C C   . ILE A 1 551 ? 177.491 159.366 120.906 1.00 87.19  ? 551 ILE A C   1 
ATOM   2568 O O   . ILE A 1 551 ? 177.039 160.055 119.984 1.00 86.50  ? 551 ILE A O   1 
ATOM   2569 C CB  . ILE A 1 551 ? 179.176 160.860 122.047 1.00 91.07  ? 551 ILE A CB  1 
ATOM   2570 C CG1 . ILE A 1 551 ? 180.570 160.884 122.672 1.00 88.25  ? 551 ILE A CG1 1 
ATOM   2571 C CG2 . ILE A 1 551 ? 178.110 161.107 123.096 1.00 90.55  ? 551 ILE A CG2 1 
ATOM   2572 C CD1 . ILE A 1 551 ? 180.853 159.694 123.548 1.00 80.87  ? 551 ILE A CD1 1 
ATOM   2573 N N   . VAL A 1 552 ? 176.768 158.466 121.568 1.00 86.20  ? 552 VAL A N   1 
ATOM   2574 C CA  . VAL A 1 552 ? 175.386 158.180 121.209 1.00 85.06  ? 552 VAL A CA  1 
ATOM   2575 C C   . VAL A 1 552 ? 174.387 158.674 122.247 1.00 84.92  ? 552 VAL A C   1 
ATOM   2576 O O   . VAL A 1 552 ? 173.189 158.756 121.934 1.00 84.66  ? 552 VAL A O   1 
ATOM   2577 C CB  . VAL A 1 552 ? 175.179 156.674 120.950 1.00 82.79  ? 552 VAL A CB  1 
ATOM   2578 C CG1 . VAL A 1 552 ? 176.063 156.208 119.805 1.00 84.51  ? 552 VAL A CG1 1 
ATOM   2579 C CG2 . VAL A 1 552 ? 175.470 155.877 122.208 1.00 78.00  ? 552 VAL A CG2 1 
ATOM   2580 N N   . TYR A 1 553 ? 174.824 159.006 123.457 1.00 82.55  ? 553 TYR A N   1 
ATOM   2581 C CA  . TYR A 1 553 ? 173.882 159.457 124.471 1.00 82.65  ? 553 TYR A CA  1 
ATOM   2582 C C   . TYR A 1 553 ? 173.470 160.904 124.203 1.00 88.64  ? 553 TYR A C   1 
ATOM   2583 O O   . TYR A 1 553 ? 174.286 161.707 123.740 1.00 90.76  ? 553 TYR A O   1 
ATOM   2584 C CB  . TYR A 1 553 ? 174.481 159.323 125.871 1.00 79.88  ? 553 TYR A CB  1 
ATOM   2585 C CG  . TYR A 1 553 ? 174.524 157.896 126.374 1.00 75.85  ? 553 TYR A CG  1 
ATOM   2586 C CD1 . TYR A 1 553 ? 174.470 156.826 125.490 1.00 73.92  ? 553 TYR A CD1 1 
ATOM   2587 C CD2 . TYR A 1 553 ? 174.597 157.618 127.730 1.00 75.56  ? 553 TYR A CD2 1 
ATOM   2588 C CE1 . TYR A 1 553 ? 174.504 155.524 125.937 1.00 68.59  ? 553 TYR A CE1 1 
ATOM   2589 C CE2 . TYR A 1 553 ? 174.630 156.313 128.188 1.00 73.91  ? 553 TYR A CE2 1 
ATOM   2590 C CZ  . TYR A 1 553 ? 174.582 155.271 127.283 1.00 69.18  ? 553 TYR A CZ  1 
ATOM   2591 O OH  . TYR A 1 553 ? 174.613 153.967 127.718 1.00 63.05  ? 553 TYR A OH  1 
ATOM   2592 N N   . PRO A 1 554 ? 172.212 161.261 124.476 1.00 93.30  ? 554 PRO A N   1 
ATOM   2593 C CA  . PRO A 1 554 ? 171.737 162.607 124.112 1.00 98.92  ? 554 PRO A CA  1 
ATOM   2594 C C   . PRO A 1 554 ? 172.500 163.742 124.776 1.00 98.15  ? 554 PRO A C   1 
ATOM   2595 O O   . PRO A 1 554 ? 172.682 164.796 124.155 1.00 99.93  ? 554 PRO A O   1 
ATOM   2596 C CB  . PRO A 1 554 ? 170.265 162.582 124.550 1.00 98.76  ? 554 PRO A CB  1 
ATOM   2597 C CG  . PRO A 1 554 ? 169.895 161.136 124.546 1.00 94.44  ? 554 PRO A CG  1 
ATOM   2598 C CD  . PRO A 1 554 ? 171.126 160.410 124.991 1.00 92.23  ? 554 PRO A CD  1 
ATOM   2599 N N   . GLN A 1 555 ? 172.949 163.568 126.015 1.00 96.25  ? 555 GLN A N   1 
ATOM   2600 C CA  . GLN A 1 555 ? 173.625 164.626 126.753 1.00 96.79  ? 555 GLN A CA  1 
ATOM   2601 C C   . GLN A 1 555 ? 175.039 164.190 127.100 1.00 93.70  ? 555 GLN A C   1 
ATOM   2602 O O   . GLN A 1 555 ? 175.243 163.096 127.633 1.00 93.46  ? 555 GLN A O   1 
ATOM   2603 C CB  . GLN A 1 555 ? 172.856 164.996 128.023 1.00 96.34  ? 555 GLN A CB  1 
ATOM   2604 C CG  . GLN A 1 555 ? 171.491 165.615 127.761 1.00 99.44  ? 555 GLN A CG  1 
ATOM   2605 C CD  . GLN A 1 555 ? 171.574 166.937 127.018 1.00 101.32 ? 555 GLN A CD  1 
ATOM   2606 O OE1 . GLN A 1 555 ? 172.603 167.612 127.036 1.00 105.90 ? 555 GLN A OE1 1 
ATOM   2607 N NE2 . GLN A 1 555 ? 170.485 167.312 126.357 1.00 97.87  ? 555 GLN A NE2 1 
ATOM   2608 N N   . LYS A 1 556 ? 176.010 165.053 126.797 1.00 92.84  ? 556 LYS A N   1 
ATOM   2609 C CA  . LYS A 1 556 ? 177.408 164.716 127.038 1.00 89.68  ? 556 LYS A CA  1 
ATOM   2610 C C   . LYS A 1 556 ? 177.744 164.768 128.524 1.00 88.12  ? 556 LYS A C   1 
ATOM   2611 O O   . LYS A 1 556 ? 178.583 163.994 129.003 1.00 90.52  ? 556 LYS A O   1 
ATOM   2612 C CB  . LYS A 1 556 ? 178.312 165.654 126.239 1.00 95.15  ? 556 LYS A CB  1 
ATOM   2613 C CG  . LYS A 1 556 ? 179.788 165.313 126.313 1.00 94.92  ? 556 LYS A CG  1 
ATOM   2614 C CD  . LYS A 1 556 ? 180.554 165.890 125.132 1.00 101.72 ? 556 LYS A CD  1 
ATOM   2615 C CE  . LYS A 1 556 ? 180.356 167.391 125.015 1.00 104.55 ? 556 LYS A CE  1 
ATOM   2616 N NZ  . LYS A 1 556 ? 181.071 167.946 123.833 1.00 107.72 ? 556 LYS A NZ  1 
ATOM   2617 N N   . ALA A 1 557 ? 177.090 165.661 129.271 1.00 88.12  ? 557 ALA A N   1 
ATOM   2618 C CA  . ALA A 1 557 ? 177.367 165.783 130.699 1.00 87.49  ? 557 ALA A CA  1 
ATOM   2619 C C   . ALA A 1 557 ? 177.164 164.463 131.426 1.00 84.12  ? 557 ALA A C   1 
ATOM   2620 O O   . ALA A 1 557 ? 177.843 164.197 132.425 1.00 82.99  ? 557 ALA A O   1 
ATOM   2621 C CB  . ALA A 1 557 ? 176.484 166.866 131.317 1.00 88.03  ? 557 ALA A CB  1 
ATOM   2622 N N   . TYR A 1 558 ? 176.258 163.618 130.922 1.00 84.74  ? 558 TYR A N   1 
ATOM   2623 C CA  . TYR A 1 558 ? 176.031 162.305 131.517 1.00 81.74  ? 558 TYR A CA  1 
ATOM   2624 C C   . TYR A 1 558 ? 177.334 161.544 131.695 1.00 83.61  ? 558 TYR A C   1 
ATOM   2625 O O   . TYR A 1 558 ? 177.534 160.870 132.711 1.00 87.70  ? 558 TYR A O   1 
ATOM   2626 C CB  . TYR A 1 558 ? 175.071 161.493 130.647 1.00 86.00  ? 558 TYR A CB  1 
ATOM   2627 C CG  . TYR A 1 558 ? 173.642 161.974 130.673 1.00 87.96  ? 558 TYR A CG  1 
ATOM   2628 C CD1 . TYR A 1 558 ? 173.131 162.633 131.781 1.00 85.66  ? 558 TYR A CD1 1 
ATOM   2629 C CD2 . TYR A 1 558 ? 172.801 161.760 129.589 1.00 87.60  ? 558 TYR A CD2 1 
ATOM   2630 C CE1 . TYR A 1 558 ? 171.826 163.068 131.810 1.00 91.89  ? 558 TYR A CE1 1 
ATOM   2631 C CE2 . TYR A 1 558 ? 171.496 162.190 129.608 1.00 90.80  ? 558 TYR A CE2 1 
ATOM   2632 C CZ  . TYR A 1 558 ? 171.013 162.845 130.720 1.00 98.81  ? 558 TYR A CZ  1 
ATOM   2633 O OH  . TYR A 1 558 ? 169.708 163.279 130.745 1.00 109.35 ? 558 TYR A OH  1 
ATOM   2634 N N   . TYR A 1 559 ? 178.234 161.639 130.715 1.00 82.30  ? 559 TYR A N   1 
ATOM   2635 C CA  . TYR A 1 559 ? 179.529 160.983 130.848 1.00 77.43  ? 559 TYR A CA  1 
ATOM   2636 C C   . TYR A 1 559 ? 180.314 161.558 132.018 1.00 81.05  ? 559 TYR A C   1 
ATOM   2637 O O   . TYR A 1 559 ? 180.765 160.819 132.901 1.00 83.01  ? 559 TYR A O   1 
ATOM   2638 C CB  . TYR A 1 559 ? 180.326 161.128 129.555 1.00 76.93  ? 559 TYR A CB  1 
ATOM   2639 C CG  . TYR A 1 559 ? 179.734 160.416 128.366 1.00 76.04  ? 559 TYR A CG  1 
ATOM   2640 C CD1 . TYR A 1 559 ? 178.689 160.974 127.648 1.00 76.14  ? 559 TYR A CD1 1 
ATOM   2641 C CD2 . TYR A 1 559 ? 180.237 159.196 127.947 1.00 77.35  ? 559 TYR A CD2 1 
ATOM   2642 C CE1 . TYR A 1 559 ? 178.154 160.331 126.554 1.00 77.64  ? 559 TYR A CE1 1 
ATOM   2643 C CE2 . TYR A 1 559 ? 179.710 158.546 126.853 1.00 76.81  ? 559 TYR A CE2 1 
ATOM   2644 C CZ  . TYR A 1 559 ? 178.669 159.117 126.160 1.00 76.96  ? 559 TYR A CZ  1 
ATOM   2645 O OH  . TYR A 1 559 ? 178.141 158.467 125.070 1.00 81.28  ? 559 TYR A OH  1 
ATOM   2646 N N   . TYR A 1 560 ? 180.458 162.886 132.056 1.00 84.19  ? 560 TYR A N   1 
ATOM   2647 C CA  . TYR A 1 560 ? 181.392 163.504 132.993 1.00 86.29  ? 560 TYR A CA  1 
ATOM   2648 C C   . TYR A 1 560 ? 181.012 163.203 134.434 1.00 85.93  ? 560 TYR A C   1 
ATOM   2649 O O   . TYR A 1 560 ? 181.873 162.834 135.244 1.00 83.29  ? 560 TYR A O   1 
ATOM   2650 C CB  . TYR A 1 560 ? 181.459 165.010 132.747 1.00 92.39  ? 560 TYR A CB  1 
ATOM   2651 C CG  . TYR A 1 560 ? 182.052 165.361 131.405 1.00 94.42  ? 560 TYR A CG  1 
ATOM   2652 C CD1 . TYR A 1 560 ? 183.425 165.405 131.225 1.00 98.10  ? 560 TYR A CD1 1 
ATOM   2653 C CD2 . TYR A 1 560 ? 181.240 165.633 130.314 1.00 92.68  ? 560 TYR A CD2 1 
ATOM   2654 C CE1 . TYR A 1 560 ? 183.975 165.717 130.000 1.00 101.63 ? 560 TYR A CE1 1 
ATOM   2655 C CE2 . TYR A 1 560 ? 181.782 165.946 129.083 1.00 93.17  ? 560 TYR A CE2 1 
ATOM   2656 C CZ  . TYR A 1 560 ? 183.150 165.986 128.932 1.00 98.78  ? 560 TYR A CZ  1 
ATOM   2657 O OH  . TYR A 1 560 ? 183.702 166.296 127.711 1.00 101.39 ? 560 TYR A OH  1 
ATOM   2658 N N   . CYS A 1 561 ? 179.724 163.321 134.764 1.00 87.29  ? 561 CYS A N   1 
ATOM   2659 C CA  . CYS A 1 561 ? 179.267 162.954 136.099 1.00 86.70  ? 561 CYS A CA  1 
ATOM   2660 C C   . CYS A 1 561 ? 179.743 161.556 136.456 1.00 85.08  ? 561 CYS A C   1 
ATOM   2661 O O   . CYS A 1 561 ? 180.363 161.345 137.506 1.00 84.37  ? 561 CYS A O   1 
ATOM   2662 C CB  . CYS A 1 561 ? 177.743 163.035 136.172 1.00 88.75  ? 561 CYS A CB  1 
ATOM   2663 S SG  . CYS A 1 561 ? 177.037 164.527 135.446 1.00 84.60  ? 561 CYS A SG  1 
ATOM   2664 N N   . ALA A 1 562 ? 179.522 160.601 135.554 1.00 83.32  ? 562 ALA A N   1 
ATOM   2665 C CA  . ALA A 1 562 ? 179.957 159.229 135.764 1.00 83.57  ? 562 ALA A CA  1 
ATOM   2666 C C   . ALA A 1 562 ? 181.459 159.183 135.997 1.00 83.40  ? 562 ALA A C   1 
ATOM   2667 O O   . ALA A 1 562 ? 181.920 158.537 136.944 1.00 81.21  ? 562 ALA A O   1 
ATOM   2668 C CB  . ALA A 1 562 ? 179.573 158.358 134.569 1.00 77.09  ? 562 ALA A CB  1 
ATOM   2669 N N   . ILE A 1 563 ? 182.225 159.898 135.164 1.00 84.59  ? 563 ILE A N   1 
ATOM   2670 C CA  . ILE A 1 563 ? 183.679 159.886 135.303 1.00 80.79  ? 563 ILE A CA  1 
ATOM   2671 C C   . ILE A 1 563 ? 184.073 160.378 136.685 1.00 80.54  ? 563 ILE A C   1 
ATOM   2672 O O   . ILE A 1 563 ? 185.060 159.918 137.271 1.00 79.18  ? 563 ILE A O   1 
ATOM   2673 C CB  . ILE A 1 563 ? 184.338 160.725 134.193 1.00 75.35  ? 563 ILE A CB  1 
ATOM   2674 C CG1 . ILE A 1 563 ? 183.913 160.221 132.817 1.00 76.11  ? 563 ILE A CG1 1 
ATOM   2675 C CG2 . ILE A 1 563 ? 185.845 160.663 134.304 1.00 74.52  ? 563 ILE A CG2 1 
ATOM   2676 C CD1 . ILE A 1 563 ? 184.562 160.971 131.683 1.00 81.40  ? 563 ILE A CD1 1 
ATOM   2677 N N   . ILE A 1 564 ? 183.299 161.310 137.237 1.00 80.02  ? 564 ILE A N   1 
ATOM   2678 C CA  . ILE A 1 564 ? 183.506 161.675 138.630 1.00 79.29  ? 564 ILE A CA  1 
ATOM   2679 C C   . ILE A 1 564 ? 182.881 160.629 139.539 1.00 79.03  ? 564 ILE A C   1 
ATOM   2680 O O   . ILE A 1 564 ? 183.541 160.091 140.437 1.00 76.34  ? 564 ILE A O   1 
ATOM   2681 C CB  . ILE A 1 564 ? 182.940 163.079 138.903 1.00 81.99  ? 564 ILE A CB  1 
ATOM   2682 C CG1 . ILE A 1 564 ? 183.570 164.097 137.950 1.00 85.96  ? 564 ILE A CG1 1 
ATOM   2683 C CG2 . ILE A 1 564 ? 183.167 163.473 140.352 1.00 82.05  ? 564 ILE A CG2 1 
ATOM   2684 C CD1 . ILE A 1 564 ? 185.084 164.130 138.000 1.00 87.24  ? 564 ILE A CD1 1 
ATOM   2685 N N   . GLU A 1 565 ? 181.617 160.283 139.276 1.00 82.99  ? 565 GLU A N   1 
ATOM   2686 C CA  . GLU A 1 565 ? 180.857 159.429 140.182 1.00 83.68  ? 565 GLU A CA  1 
ATOM   2687 C C   . GLU A 1 565 ? 181.570 158.107 140.419 1.00 82.21  ? 565 GLU A C   1 
ATOM   2688 O O   . GLU A 1 565 ? 181.774 157.693 141.567 1.00 80.80  ? 565 GLU A O   1 
ATOM   2689 C CB  . GLU A 1 565 ? 179.454 159.196 139.619 1.00 81.86  ? 565 GLU A CB  1 
ATOM   2690 C CG  . GLU A 1 565 ? 178.682 158.085 140.299 1.00 87.41  ? 565 GLU A CG  1 
ATOM   2691 C CD  . GLU A 1 565 ? 178.622 156.825 139.462 1.00 92.43  ? 565 GLU A CD  1 
ATOM   2692 O OE1 . GLU A 1 565 ? 179.528 156.617 138.629 1.00 94.65  ? 565 GLU A OE1 1 
ATOM   2693 O OE2 . GLU A 1 565 ? 177.660 156.050 139.629 1.00 90.29  ? 565 GLU A OE2 1 
ATOM   2694 N N   . ASP A 1 566 ? 181.996 157.453 139.335 1.00 81.21  ? 566 ASP A N   1 
ATOM   2695 C CA  . ASP A 1 566 ? 182.711 156.190 139.439 1.00 78.45  ? 566 ASP A CA  1 
ATOM   2696 C C   . ASP A 1 566 ? 183.862 156.314 140.424 1.00 76.70  ? 566 ASP A C   1 
ATOM   2697 O O   . ASP A 1 566 ? 183.980 155.518 141.363 1.00 75.24  ? 566 ASP A O   1 
ATOM   2698 C CB  . ASP A 1 566 ? 183.219 155.764 138.058 1.00 76.64  ? 566 ASP A CB  1 
ATOM   2699 C CG  . ASP A 1 566 ? 183.899 154.410 138.073 1.00 73.80  ? 566 ASP A CG  1 
ATOM   2700 O OD1 . ASP A 1 566 ? 183.770 153.684 139.079 1.00 74.67  ? 566 ASP A OD1 1 
ATOM   2701 O OD2 . ASP A 1 566 ? 184.565 154.071 137.075 1.00 70.28  ? 566 ASP A OD2 1 
ATOM   2702 N N   . VAL A 1 567 ? 184.679 157.358 140.262 1.00 76.82  ? 567 VAL A N   1 
ATOM   2703 C CA  . VAL A 1 567 ? 185.809 157.555 141.166 1.00 74.20  ? 567 VAL A CA  1 
ATOM   2704 C C   . VAL A 1 567 ? 185.309 157.646 142.599 1.00 71.96  ? 567 VAL A C   1 
ATOM   2705 O O   . VAL A 1 567 ? 185.746 156.898 143.481 1.00 73.86  ? 567 VAL A O   1 
ATOM   2706 C CB  . VAL A 1 567 ? 186.605 158.808 140.771 1.00 74.83  ? 567 VAL A CB  1 
ATOM   2707 C CG1 . VAL A 1 567 ? 187.734 159.043 141.754 1.00 73.49  ? 567 VAL A CG1 1 
ATOM   2708 C CG2 . VAL A 1 567 ? 187.144 158.666 139.362 1.00 72.23  ? 567 VAL A CG2 1 
ATOM   2709 N N   . ILE A 1 568 ? 184.314 158.506 142.824 1.00 69.65  ? 568 ILE A N   1 
ATOM   2710 C CA  . ILE A 1 568 ? 183.798 158.707 144.173 1.00 67.89  ? 568 ILE A CA  1 
ATOM   2711 C C   . ILE A 1 568 ? 183.294 157.392 144.739 1.00 69.05  ? 568 ILE A C   1 
ATOM   2712 O O   . ILE A 1 568 ? 183.375 157.143 145.948 1.00 74.47  ? 568 ILE A O   1 
ATOM   2713 C CB  . ILE A 1 568 ? 182.698 159.784 144.168 1.00 71.26  ? 568 ILE A CB  1 
ATOM   2714 C CG1 . ILE A 1 568 ? 183.245 161.100 143.618 1.00 71.59  ? 568 ILE A CG1 1 
ATOM   2715 C CG2 . ILE A 1 568 ? 182.141 159.994 145.564 1.00 74.28  ? 568 ILE A CG2 1 
ATOM   2716 C CD1 . ILE A 1 568 ? 182.257 162.237 143.687 1.00 61.26  ? 568 ILE A CD1 1 
ATOM   2717 N N   . LEU A 1 569 ? 182.789 156.517 143.872 1.00 68.03  ? 569 LEU A N   1 
ATOM   2718 C CA  . LEU A 1 569 ? 182.299 155.226 144.324 1.00 69.38  ? 569 LEU A CA  1 
ATOM   2719 C C   . LEU A 1 569 ? 183.356 154.137 144.273 1.00 70.61  ? 569 LEU A C   1 
ATOM   2720 O O   . LEU A 1 569 ? 183.271 153.181 145.051 1.00 71.09  ? 569 LEU A O   1 
ATOM   2721 C CB  . LEU A 1 569 ? 181.083 154.804 143.497 1.00 70.97  ? 569 LEU A CB  1 
ATOM   2722 C CG  . LEU A 1 569 ? 179.795 155.546 143.854 1.00 67.27  ? 569 LEU A CG  1 
ATOM   2723 C CD1 . LEU A 1 569 ? 178.671 155.197 142.900 1.00 65.87  ? 569 LEU A CD1 1 
ATOM   2724 C CD2 . LEU A 1 569 ? 179.402 155.232 145.285 1.00 67.57  ? 569 LEU A CD2 1 
ATOM   2725 N N   . ARG A 1 570 ? 184.361 154.268 143.400 1.00 70.80  ? 570 ARG A N   1 
ATOM   2726 C CA  . ARG A 1 570 ? 185.336 153.191 143.255 1.00 67.90  ? 570 ARG A CA  1 
ATOM   2727 C C   . ARG A 1 570 ? 186.085 152.934 144.551 1.00 69.55  ? 570 ARG A C   1 
ATOM   2728 O O   . ARG A 1 570 ? 186.138 151.791 145.018 1.00 74.12  ? 570 ARG A O   1 
ATOM   2729 C CB  . ARG A 1 570 ? 186.327 153.515 142.147 1.00 69.19  ? 570 ARG A CB  1 
ATOM   2730 C CG  . ARG A 1 570 ? 187.327 152.416 141.926 1.00 73.98  ? 570 ARG A CG  1 
ATOM   2731 C CD  . ARG A 1 570 ? 186.645 151.217 141.326 1.00 75.37  ? 570 ARG A CD  1 
ATOM   2732 N NE  . ARG A 1 570 ? 186.093 151.538 140.018 1.00 72.54  ? 570 ARG A NE  1 
ATOM   2733 C CZ  . ARG A 1 570 ? 185.463 150.670 139.241 1.00 73.30  ? 570 ARG A CZ  1 
ATOM   2734 N NH1 . ARG A 1 570 ? 185.281 149.415 139.614 1.00 71.11  ? 570 ARG A NH1 1 
ATOM   2735 N NH2 . ARG A 1 570 ? 185.003 151.072 138.062 1.00 74.92  ? 570 ARG A NH2 1 
ATOM   2736 N N   . PHE A 1 571 ? 186.655 153.979 145.147 1.00 70.40  ? 571 PHE A N   1 
ATOM   2737 C CA  . PHE A 1 571 ? 187.228 153.842 146.477 1.00 70.94  ? 571 PHE A CA  1 
ATOM   2738 C C   . PHE A 1 571 ? 186.185 153.321 147.454 1.00 69.70  ? 571 PHE A C   1 
ATOM   2739 O O   . PHE A 1 571 ? 186.470 152.425 148.257 1.00 74.24  ? 571 PHE A O   1 
ATOM   2740 C CB  . PHE A 1 571 ? 187.788 155.185 146.944 1.00 73.00  ? 571 PHE A CB  1 
ATOM   2741 C CG  . PHE A 1 571 ? 188.836 155.758 146.031 1.00 70.94  ? 571 PHE A CG  1 
ATOM   2742 C CD1 . PHE A 1 571 ? 190.180 155.611 146.320 1.00 70.26  ? 571 PHE A CD1 1 
ATOM   2743 C CD2 . PHE A 1 571 ? 188.477 156.446 144.887 1.00 71.14  ? 571 PHE A CD2 1 
ATOM   2744 C CE1 . PHE A 1 571 ? 191.143 156.137 145.482 1.00 67.78  ? 571 PHE A CE1 1 
ATOM   2745 C CE2 . PHE A 1 571 ? 189.436 156.970 144.048 1.00 70.80  ? 571 PHE A CE2 1 
ATOM   2746 C CZ  . PHE A 1 571 ? 190.769 156.817 144.345 1.00 67.21  ? 571 PHE A CZ  1 
ATOM   2747 N N   . ALA A 1 572 ? 184.956 153.833 147.358 1.00 65.37  ? 572 ALA A N   1 
ATOM   2748 C CA  . ALA A 1 572 ? 183.880 153.362 148.218 1.00 69.78  ? 572 ALA A CA  1 
ATOM   2749 C C   . ALA A 1 572 ? 183.646 151.867 148.079 1.00 72.27  ? 572 ALA A C   1 
ATOM   2750 O O   . ALA A 1 572 ? 183.165 151.237 149.027 1.00 72.90  ? 572 ALA A O   1 
ATOM   2751 C CB  . ALA A 1 572 ? 182.591 154.120 147.906 1.00 74.47  ? 572 ALA A CB  1 
ATOM   2752 N N   . TRP A 1 573 ? 183.972 151.282 146.925 1.00 75.99  ? 573 TRP A N   1 
ATOM   2753 C CA  . TRP A 1 573 ? 183.879 149.834 146.793 1.00 75.94  ? 573 TRP A CA  1 
ATOM   2754 C C   . TRP A 1 573 ? 185.036 149.144 147.501 1.00 73.90  ? 573 TRP A C   1 
ATOM   2755 O O   . TRP A 1 573 ? 184.828 148.196 148.266 1.00 77.58  ? 573 TRP A O   1 
ATOM   2756 C CB  . TRP A 1 573 ? 183.846 149.438 145.315 1.00 77.82  ? 573 TRP A CB  1 
ATOM   2757 C CG  . TRP A 1 573 ? 184.007 147.965 145.077 1.00 76.64  ? 573 TRP A CG  1 
ATOM   2758 C CD1 . TRP A 1 573 ? 183.122 146.980 145.403 1.00 74.33  ? 573 TRP A CD1 1 
ATOM   2759 C CD2 . TRP A 1 573 ? 185.116 147.315 144.450 1.00 78.99  ? 573 TRP A CD2 1 
ATOM   2760 N NE1 . TRP A 1 573 ? 183.615 145.757 145.026 1.00 72.04  ? 573 TRP A NE1 1 
ATOM   2761 C CE2 . TRP A 1 573 ? 184.839 145.935 144.439 1.00 77.24  ? 573 TRP A CE2 1 
ATOM   2762 C CE3 . TRP A 1 573 ? 186.319 147.765 143.901 1.00 81.15  ? 573 TRP A CE3 1 
ATOM   2763 C CZ2 . TRP A 1 573 ? 185.720 145.003 143.900 1.00 77.38  ? 573 TRP A CZ2 1 
ATOM   2764 C CZ3 . TRP A 1 573 ? 187.193 146.838 143.369 1.00 84.05  ? 573 TRP A CZ3 1 
ATOM   2765 C CH2 . TRP A 1 573 ? 186.888 145.473 143.371 1.00 78.24  ? 573 TRP A CH2 1 
ATOM   2766 N N   . THR A 1 574 ? 186.258 149.637 147.288 1.00 73.72  ? 574 THR A N   1 
ATOM   2767 C CA  . THR A 1 574 ? 187.436 148.896 147.724 1.00 72.94  ? 574 THR A CA  1 
ATOM   2768 C C   . THR A 1 574 ? 187.485 148.774 149.239 1.00 76.79  ? 574 THR A C   1 
ATOM   2769 O O   . THR A 1 574 ? 187.920 147.747 149.773 1.00 76.78  ? 574 THR A O   1 
ATOM   2770 C CB  . THR A 1 574 ? 188.702 149.565 147.200 1.00 78.81  ? 574 THR A CB  1 
ATOM   2771 O OG1 . THR A 1 574 ? 188.544 149.852 145.807 1.00 81.34  ? 574 THR A OG1 1 
ATOM   2772 C CG2 . THR A 1 574 ? 189.893 148.644 147.384 1.00 85.31  ? 574 THR A CG2 1 
ATOM   2773 N N   . ILE A 1 575 ? 187.055 149.816 149.950 1.00 81.04  ? 575 ILE A N   1 
ATOM   2774 C CA  . ILE A 1 575 ? 186.981 149.734 151.405 1.00 81.29  ? 575 ILE A CA  1 
ATOM   2775 C C   . ILE A 1 575 ? 185.960 148.684 151.823 1.00 81.19  ? 575 ILE A C   1 
ATOM   2776 O O   . ILE A 1 575 ? 186.216 147.872 152.722 1.00 84.93  ? 575 ILE A O   1 
ATOM   2777 C CB  . ILE A 1 575 ? 186.667 151.119 152.006 1.00 77.09  ? 575 ILE A CB  1 
ATOM   2778 C CG1 . ILE A 1 575 ? 186.463 151.017 153.518 1.00 77.51  ? 575 ILE A CG1 1 
ATOM   2779 C CG2 . ILE A 1 575 ? 185.455 151.749 151.332 1.00 76.82  ? 575 ILE A CG2 1 
ATOM   2780 C CD1 . ILE A 1 575 ? 187.701 150.598 154.268 1.00 74.73  ? 575 ILE A CD1 1 
ATOM   2781 N N   . GLN A 1 576 ? 184.803 148.660 151.155 1.00 76.96  ? 576 GLN A N   1 
ATOM   2782 C CA  . GLN A 1 576 ? 183.750 147.721 151.528 1.00 76.87  ? 576 GLN A CA  1 
ATOM   2783 C C   . GLN A 1 576 ? 184.249 146.285 151.462 1.00 79.57  ? 576 GLN A C   1 
ATOM   2784 O O   . GLN A 1 576 ? 184.140 145.533 152.439 1.00 84.91  ? 576 GLN A O   1 
ATOM   2785 C CB  . GLN A 1 576 ? 182.536 147.907 150.622 1.00 76.54  ? 576 GLN A CB  1 
ATOM   2786 C CG  . GLN A 1 576 ? 181.505 146.808 150.766 1.00 78.01  ? 576 GLN A CG  1 
ATOM   2787 C CD  . GLN A 1 576 ? 180.473 146.837 149.664 1.00 80.78  ? 576 GLN A CD  1 
ATOM   2788 O OE1 . GLN A 1 576 ? 179.967 147.896 149.300 1.00 82.53  ? 576 GLN A OE1 1 
ATOM   2789 N NE2 . GLN A 1 576 ? 180.161 145.670 149.117 1.00 83.85  ? 576 GLN A NE2 1 
ATOM   2790 N N   . ILE A 1 577 ? 184.842 145.902 150.326 1.00 80.45  ? 577 ILE A N   1 
ATOM   2791 C CA  . ILE A 1 577 ? 185.381 144.555 150.157 1.00 77.63  ? 577 ILE A CA  1 
ATOM   2792 C C   . ILE A 1 577 ? 186.270 144.180 151.328 1.00 78.45  ? 577 ILE A C   1 
ATOM   2793 O O   . ILE A 1 577 ? 186.298 143.018 151.753 1.00 79.57  ? 577 ILE A O   1 
ATOM   2794 C CB  . ILE A 1 577 ? 186.143 144.456 148.819 1.00 74.77  ? 577 ILE A CB  1 
ATOM   2795 C CG1 . ILE A 1 577 ? 185.186 144.657 147.648 1.00 71.68  ? 577 ILE A CG1 1 
ATOM   2796 C CG2 . ILE A 1 577 ? 186.854 143.123 148.698 1.00 74.20  ? 577 ILE A CG2 1 
ATOM   2797 C CD1 . ILE A 1 577 ? 184.046 143.677 147.628 1.00 78.90  ? 577 ILE A CD1 1 
ATOM   2798 N N   . SER A 1 578 ? 186.980 145.153 151.893 1.00 78.84  ? 578 SER A N   1 
ATOM   2799 C CA  . SER A 1 578 ? 187.829 144.855 153.038 1.00 80.80  ? 578 SER A CA  1 
ATOM   2800 C C   . SER A 1 578 ? 186.999 144.640 154.297 1.00 84.69  ? 578 SER A C   1 
ATOM   2801 O O   . SER A 1 578 ? 187.117 143.600 154.955 1.00 89.13  ? 578 SER A O   1 
ATOM   2802 C CB  . SER A 1 578 ? 188.848 145.974 153.240 1.00 80.20  ? 578 SER A CB  1 
ATOM   2803 O OG  . SER A 1 578 ? 189.665 146.124 152.093 1.00 75.44  ? 578 SER A OG  1 
ATOM   2804 N N   . ILE A 1 579 ? 186.127 145.596 154.631 1.00 83.78  ? 579 ILE A N   1 
ATOM   2805 C CA  . ILE A 1 579 ? 185.569 145.649 155.982 1.00 84.85  ? 579 ILE A CA  1 
ATOM   2806 C C   . ILE A 1 579 ? 184.733 144.408 156.278 1.00 91.08  ? 579 ILE A C   1 
ATOM   2807 O O   . ILE A 1 579 ? 184.882 143.781 157.334 1.00 96.62  ? 579 ILE A O   1 
ATOM   2808 C CB  . ILE A 1 579 ? 184.762 146.944 156.187 1.00 79.21  ? 579 ILE A CB  1 
ATOM   2809 C CG1 . ILE A 1 579 ? 183.724 147.122 155.082 1.00 77.96  ? 579 ILE A CG1 1 
ATOM   2810 C CG2 . ILE A 1 579 ? 185.691 148.145 156.240 1.00 79.29  ? 579 ILE A CG2 1 
ATOM   2811 C CD1 . ILE A 1 579 ? 182.862 148.340 155.248 1.00 81.15  ? 579 ILE A CD1 1 
ATOM   2812 N N   . THR A 1 580 ? 183.860 144.018 155.345 1.00 90.28  ? 580 THR A N   1 
ATOM   2813 C CA  . THR A 1 580 ? 183.041 142.830 155.560 1.00 90.49  ? 580 THR A CA  1 
ATOM   2814 C C   . THR A 1 580 ? 183.899 141.582 155.712 1.00 96.35  ? 580 THR A C   1 
ATOM   2815 O O   . THR A 1 580 ? 183.521 140.652 156.433 1.00 99.67  ? 580 THR A O   1 
ATOM   2816 C CB  . THR A 1 580 ? 182.049 142.651 154.410 1.00 87.99  ? 580 THR A CB  1 
ATOM   2817 O OG1 . THR A 1 580 ? 182.763 142.532 153.174 1.00 92.63  ? 580 THR A OG1 1 
ATOM   2818 C CG2 . THR A 1 580 ? 181.107 143.839 154.331 1.00 82.25  ? 580 THR A CG2 1 
ATOM   2819 N N   . SER A 1 581 ? 185.055 141.545 155.056 1.00 95.37  ? 581 SER A N   1 
ATOM   2820 C CA  . SER A 1 581 ? 185.972 140.425 155.190 1.00 95.37  ? 581 SER A CA  1 
ATOM   2821 C C   . SER A 1 581 ? 186.999 140.629 156.293 1.00 97.64  ? 581 SER A C   1 
ATOM   2822 O O   . SER A 1 581 ? 187.802 139.725 156.543 1.00 99.00  ? 581 SER A O   1 
ATOM   2823 C CB  . SER A 1 581 ? 186.696 140.174 153.864 1.00 92.36  ? 581 SER A CB  1 
ATOM   2824 O OG  . SER A 1 581 ? 187.398 141.329 153.444 1.00 92.58  ? 581 SER A OG  1 
ATOM   2825 N N   . THR A 1 582 ? 186.992 141.780 156.962 1.00 99.47  ? 582 THR A N   1 
ATOM   2826 C CA  . THR A 1 582 ? 188.000 142.089 157.968 1.00 102.50 ? 582 THR A CA  1 
ATOM   2827 C C   . THR A 1 582 ? 187.473 142.000 159.391 1.00 108.33 ? 582 THR A C   1 
ATOM   2828 O O   . THR A 1 582 ? 188.179 141.504 160.274 1.00 110.46 ? 582 THR A O   1 
ATOM   2829 C CB  . THR A 1 582 ? 188.567 143.493 157.736 1.00 104.33 ? 582 THR A CB  1 
ATOM   2830 O OG1 . THR A 1 582 ? 188.912 143.644 156.356 1.00 100.20 ? 582 THR A OG1 1 
ATOM   2831 C CG2 . THR A 1 582 ? 189.810 143.713 158.573 1.00 110.43 ? 582 THR A CG2 1 
ATOM   2832 N N   . THR A 1 583 ? 186.246 142.465 159.631 1.00 110.63 ? 583 THR A N   1 
ATOM   2833 C CA  . THR A 1 583 ? 185.701 142.605 160.983 1.00 117.67 ? 583 THR A CA  1 
ATOM   2834 C C   . THR A 1 583 ? 186.609 143.473 161.850 1.00 119.54 ? 583 THR A C   1 
ATOM   2835 O O   . THR A 1 583 ? 186.724 143.267 163.060 1.00 124.14 ? 583 THR A O   1 
ATOM   2836 C CB  . THR A 1 583 ? 185.462 141.243 161.644 1.00 119.42 ? 583 THR A CB  1 
ATOM   2837 O OG1 . THR A 1 583 ? 186.718 140.595 161.885 1.00 115.16 ? 583 THR A OG1 1 
ATOM   2838 C CG2 . THR A 1 583 ? 184.603 140.357 160.753 1.00 116.90 ? 583 THR A CG2 1 
ATOM   2839 N N   . LEU A 1 584 ? 187.266 144.450 161.222 1.00 116.92 ? 584 LEU A N   1 
ATOM   2840 C CA  . LEU A 1 584 ? 188.161 145.340 161.954 1.00 119.36 ? 584 LEU A CA  1 
ATOM   2841 C C   . LEU A 1 584 ? 187.397 146.214 162.938 1.00 124.48 ? 584 LEU A C   1 
ATOM   2842 O O   . LEU A 1 584 ? 187.830 146.397 164.081 1.00 126.63 ? 584 LEU A O   1 
ATOM   2843 C CB  . LEU A 1 584 ? 188.948 146.213 160.977 1.00 119.63 ? 584 LEU A CB  1 
ATOM   2844 C CG  . LEU A 1 584 ? 189.661 147.427 161.576 1.00 122.58 ? 584 LEU A CG  1 
ATOM   2845 C CD1 . LEU A 1 584 ? 190.773 146.986 162.507 1.00 123.02 ? 584 LEU A CD1 1 
ATOM   2846 C CD2 . LEU A 1 584 ? 190.197 148.337 160.484 1.00 123.69 ? 584 LEU A CD2 1 
ATOM   2847 N N   . LEU A 1 585 ? 186.258 146.759 162.515 1.00 125.24 ? 585 LEU A N   1 
ATOM   2848 C CA  . LEU A 1 585 ? 185.546 147.739 163.317 1.00 127.33 ? 585 LEU A CA  1 
ATOM   2849 C C   . LEU A 1 585 ? 184.376 147.074 164.021 1.00 129.61 ? 585 LEU A C   1 
ATOM   2850 O O   . LEU A 1 585 ? 183.391 146.714 163.358 1.00 125.96 ? 585 LEU A O   1 
ATOM   2851 C CB  . LEU A 1 585 ? 185.055 148.886 162.438 1.00 121.56 ? 585 LEU A CB  1 
ATOM   2852 C CG  . LEU A 1 585 ? 186.137 149.570 161.600 1.00 117.85 ? 585 LEU A CG  1 
ATOM   2853 C CD1 . LEU A 1 585 ? 185.543 150.667 160.734 1.00 111.99 ? 585 LEU A CD1 1 
ATOM   2854 C CD2 . LEU A 1 585 ? 187.228 150.124 162.500 1.00 119.06 ? 585 LEU A CD2 1 
ATOM   2855 N N   . PRO A 1 586 ? 184.427 146.887 165.342 1.00 134.29 ? 586 PRO A N   1 
ATOM   2856 C CA  . PRO A 1 586 ? 183.241 146.392 166.056 1.00 132.62 ? 586 PRO A CA  1 
ATOM   2857 C C   . PRO A 1 586 ? 182.078 147.363 166.020 1.00 131.22 ? 586 PRO A C   1 
ATOM   2858 O O   . PRO A 1 586 ? 180.935 146.948 166.245 1.00 129.23 ? 586 PRO A O   1 
ATOM   2859 C CB  . PRO A 1 586 ? 183.754 146.185 167.487 1.00 134.90 ? 586 PRO A CB  1 
ATOM   2860 C CG  . PRO A 1 586 ? 184.899 147.137 167.610 1.00 135.48 ? 586 PRO A CG  1 
ATOM   2861 C CD  . PRO A 1 586 ? 185.547 147.174 166.255 1.00 134.71 ? 586 PRO A CD  1 
ATOM   2862 N N   . HIS A 1 587 ? 182.335 148.639 165.747 1.00 130.05 ? 587 HIS A N   1 
ATOM   2863 C CA  . HIS A 1 587 ? 181.305 149.658 165.635 1.00 128.81 ? 587 HIS A CA  1 
ATOM   2864 C C   . HIS A 1 587 ? 181.522 150.432 164.345 1.00 126.64 ? 587 HIS A C   1 
ATOM   2865 O O   . HIS A 1 587 ? 182.663 150.627 163.913 1.00 125.02 ? 587 HIS A O   1 
ATOM   2866 C CB  . HIS A 1 587 ? 181.331 150.608 166.840 1.00 131.72 ? 587 HIS A CB  1 
ATOM   2867 C CG  . HIS A 1 587 ? 180.404 151.777 166.712 1.00 131.55 ? 587 HIS A CG  1 
ATOM   2868 N ND1 . HIS A 1 587 ? 179.097 151.650 166.293 1.00 127.19 ? 587 HIS A ND1 1 
ATOM   2869 C CD2 . HIS A 1 587 ? 180.595 153.096 166.954 1.00 131.70 ? 587 HIS A CD2 1 
ATOM   2870 C CE1 . HIS A 1 587 ? 178.524 152.841 166.279 1.00 128.07 ? 587 HIS A CE1 1 
ATOM   2871 N NE2 . HIS A 1 587 ? 179.411 153.735 166.676 1.00 130.01 ? 587 HIS A NE2 1 
ATOM   2872 N N   . SER A 1 588 ? 180.421 150.854 163.727 1.00 126.10 ? 588 SER A N   1 
ATOM   2873 C CA  . SER A 1 588 ? 180.394 151.659 162.510 1.00 123.53 ? 588 SER A CA  1 
ATOM   2874 C C   . SER A 1 588 ? 180.949 150.933 161.293 1.00 114.13 ? 588 SER A C   1 
ATOM   2875 O O   . SER A 1 588 ? 181.291 151.584 160.298 1.00 111.11 ? 588 SER A O   1 
ATOM   2876 C CB  . SER A 1 588 ? 181.138 152.988 162.689 1.00 124.78 ? 588 SER A CB  1 
ATOM   2877 O OG  . SER A 1 588 ? 180.520 153.788 163.684 1.00 126.86 ? 588 SER A OG  1 
ATOM   2878 N N   . GLY A 1 589 ? 181.051 149.607 161.334 1.00 111.47 ? 589 GLY A N   1 
ATOM   2879 C CA  . GLY A 1 589 ? 181.471 148.858 160.166 1.00 106.31 ? 589 GLY A CA  1 
ATOM   2880 C C   . GLY A 1 589 ? 180.309 148.304 159.367 1.00 100.40 ? 589 GLY A C   1 
ATOM   2881 O O   . GLY A 1 589 ? 180.219 148.503 158.150 1.00 100.26 ? 589 GLY A O   1 
ATOM   2882 N N   . ASP A 1 590 ? 179.403 147.604 160.051 1.00 99.79  ? 590 ASP A N   1 
ATOM   2883 C CA  . ASP A 1 590 ? 178.255 147.020 159.367 1.00 99.71  ? 590 ASP A CA  1 
ATOM   2884 C C   . ASP A 1 590 ? 177.370 148.098 158.760 1.00 97.72  ? 590 ASP A C   1 
ATOM   2885 O O   . ASP A 1 590 ? 176.864 147.939 157.644 1.00 97.14  ? 590 ASP A O   1 
ATOM   2886 C CB  . ASP A 1 590 ? 177.453 146.152 160.333 1.00 103.73 ? 590 ASP A CB  1 
ATOM   2887 C CG  . ASP A 1 590 ? 178.260 144.999 160.884 1.00 109.78 ? 590 ASP A CG  1 
ATOM   2888 O OD1 . ASP A 1 590 ? 179.173 145.248 161.698 1.00 111.30 ? 590 ASP A OD1 1 
ATOM   2889 O OD2 . ASP A 1 590 ? 177.981 143.843 160.503 1.00 113.35 ? 590 ASP A OD2 1 
ATOM   2890 N N   . ILE A 1 591 ? 177.167 149.200 159.482 1.00 98.33  ? 591 ILE A N   1 
ATOM   2891 C CA  . ILE A 1 591 ? 176.317 150.269 158.969 1.00 94.59  ? 591 ILE A CA  1 
ATOM   2892 C C   . ILE A 1 591 ? 176.929 150.886 157.720 1.00 94.22  ? 591 ILE A C   1 
ATOM   2893 O O   . ILE A 1 591 ? 176.225 151.157 156.741 1.00 91.22  ? 591 ILE A O   1 
ATOM   2894 C CB  . ILE A 1 591 ? 176.056 151.325 160.060 1.00 93.93  ? 591 ILE A CB  1 
ATOM   2895 C CG1 . ILE A 1 591 ? 175.345 152.542 159.468 1.00 88.43  ? 591 ILE A CG1 1 
ATOM   2896 C CG2 . ILE A 1 591 ? 177.345 151.738 160.732 1.00 100.19 ? 591 ILE A CG2 1 
ATOM   2897 C CD1 . ILE A 1 591 ? 175.046 153.621 160.480 1.00 87.32  ? 591 ILE A CD1 1 
ATOM   2898 N N   . ILE A 1 592 ? 178.244 151.115 157.725 1.00 98.22  ? 592 ILE A N   1 
ATOM   2899 C CA  . ILE A 1 592 ? 178.866 151.720 156.551 1.00 100.36 ? 592 ILE A CA  1 
ATOM   2900 C C   . ILE A 1 592 ? 178.860 150.747 155.374 1.00 95.34  ? 592 ILE A C   1 
ATOM   2901 O O   . ILE A 1 592 ? 178.689 151.163 154.221 1.00 91.84  ? 592 ILE A O   1 
ATOM   2902 C CB  . ILE A 1 592 ? 180.281 152.237 156.883 1.00 99.31  ? 592 ILE A CB  1 
ATOM   2903 C CG1 . ILE A 1 592 ? 180.723 153.268 155.845 1.00 94.83  ? 592 ILE A CG1 1 
ATOM   2904 C CG2 . ILE A 1 592 ? 181.290 151.115 156.952 1.00 97.38  ? 592 ILE A CG2 1 
ATOM   2905 C CD1 . ILE A 1 592 ? 179.860 154.508 155.814 1.00 91.40  ? 592 ILE A CD1 1 
ATOM   2906 N N   . ALA A 1 593 ? 179.018 149.445 155.633 1.00 93.25  ? 593 ALA A N   1 
ATOM   2907 C CA  . ALA A 1 593 ? 178.908 148.471 154.551 1.00 89.27  ? 593 ALA A CA  1 
ATOM   2908 C C   . ALA A 1 593 ? 177.500 148.452 153.968 1.00 87.10  ? 593 ALA A C   1 
ATOM   2909 O O   . ALA A 1 593 ? 177.324 148.378 152.746 1.00 85.37  ? 593 ALA A O   1 
ATOM   2910 C CB  . ALA A 1 593 ? 179.300 147.081 155.051 1.00 86.94  ? 593 ALA A CB  1 
ATOM   2911 N N   . THR A 1 594 ? 176.484 148.518 154.831 1.00 84.64  ? 594 THR A N   1 
ATOM   2912 C CA  . THR A 1 594 ? 175.103 148.532 154.361 1.00 81.42  ? 594 THR A CA  1 
ATOM   2913 C C   . THR A 1 594 ? 174.801 149.801 153.576 1.00 81.93  ? 594 THR A C   1 
ATOM   2914 O O   . THR A 1 594 ? 174.033 149.774 152.609 1.00 79.67  ? 594 THR A O   1 
ATOM   2915 C CB  . THR A 1 594 ? 174.150 148.390 155.547 1.00 84.88  ? 594 THR A CB  1 
ATOM   2916 O OG1 . THR A 1 594 ? 174.362 147.121 156.176 1.00 91.06  ? 594 THR A OG1 1 
ATOM   2917 C CG2 . THR A 1 594 ? 172.706 148.481 155.093 1.00 83.93  ? 594 THR A CG2 1 
ATOM   2918 N N   . VAL A 1 595 ? 175.382 150.927 153.986 1.00 85.22  ? 595 VAL A N   1 
ATOM   2919 C CA  . VAL A 1 595 ? 175.199 152.170 153.244 1.00 86.75  ? 595 VAL A CA  1 
ATOM   2920 C C   . VAL A 1 595 ? 175.854 152.072 151.871 1.00 84.67  ? 595 VAL A C   1 
ATOM   2921 O O   . VAL A 1 595 ? 175.268 152.467 150.856 1.00 80.64  ? 595 VAL A O   1 
ATOM   2922 C CB  . VAL A 1 595 ? 175.748 153.362 154.047 1.00 86.15  ? 595 VAL A CB  1 
ATOM   2923 C CG1 . VAL A 1 595 ? 175.780 154.611 153.185 1.00 90.80  ? 595 VAL A CG1 1 
ATOM   2924 C CG2 . VAL A 1 595 ? 174.907 153.600 155.288 1.00 81.75  ? 595 VAL A CG2 1 
ATOM   2925 N N   . PHE A 1 596 ? 177.077 151.541 151.818 1.00 84.39  ? 596 PHE A N   1 
ATOM   2926 C CA  . PHE A 1 596 ? 177.832 151.509 150.572 1.00 79.35  ? 596 PHE A CA  1 
ATOM   2927 C C   . PHE A 1 596 ? 177.355 150.445 149.593 1.00 74.08  ? 596 PHE A C   1 
ATOM   2928 O O   . PHE A 1 596 ? 177.577 150.601 148.388 1.00 71.12  ? 596 PHE A O   1 
ATOM   2929 C CB  . PHE A 1 596 ? 179.317 151.290 150.863 1.00 80.74  ? 596 PHE A CB  1 
ATOM   2930 C CG  . PHE A 1 596 ? 180.016 152.508 151.384 1.00 84.68  ? 596 PHE A CG  1 
ATOM   2931 C CD1 . PHE A 1 596 ? 179.513 153.769 151.136 1.00 83.32  ? 596 PHE A CD1 1 
ATOM   2932 C CD2 . PHE A 1 596 ? 181.181 152.391 152.120 1.00 87.00  ? 596 PHE A CD2 1 
ATOM   2933 C CE1 . PHE A 1 596 ? 180.155 154.892 151.615 1.00 85.33  ? 596 PHE A CE1 1 
ATOM   2934 C CE2 . PHE A 1 596 ? 181.830 153.511 152.598 1.00 88.49  ? 596 PHE A CE2 1 
ATOM   2935 C CZ  . PHE A 1 596 ? 181.315 154.762 152.347 1.00 91.30  ? 596 PHE A CZ  1 
ATOM   2936 N N   . ALA A 1 597 ? 176.726 149.367 150.068 1.00 73.29  ? 597 ALA A N   1 
ATOM   2937 C CA  . ALA A 1 597 ? 176.365 148.277 149.163 1.00 71.58  ? 597 ALA A CA  1 
ATOM   2938 C C   . ALA A 1 597 ? 175.416 148.709 148.049 1.00 72.51  ? 597 ALA A C   1 
ATOM   2939 O O   . ALA A 1 597 ? 175.722 148.438 146.874 1.00 75.42  ? 597 ALA A O   1 
ATOM   2940 C CB  . ALA A 1 597 ? 175.799 147.105 149.971 1.00 69.33  ? 597 ALA A CB  1 
ATOM   2941 N N   . PRO A 1 598 ? 174.282 149.370 148.316 1.00 67.12  ? 598 PRO A N   1 
ATOM   2942 C CA  . PRO A 1 598 ? 173.483 149.889 147.195 1.00 62.84  ? 598 PRO A CA  1 
ATOM   2943 C C   . PRO A 1 598 ? 174.223 150.922 146.373 1.00 66.08  ? 598 PRO A C   1 
ATOM   2944 O O   . PRO A 1 598 ? 173.954 151.056 145.175 1.00 62.78  ? 598 PRO A O   1 
ATOM   2945 C CB  . PRO A 1 598 ? 172.254 150.489 147.887 1.00 58.37  ? 598 PRO A CB  1 
ATOM   2946 C CG  . PRO A 1 598 ? 172.714 150.800 149.246 1.00 68.59  ? 598 PRO A CG  1 
ATOM   2947 C CD  . PRO A 1 598 ? 173.655 149.701 149.604 1.00 66.36  ? 598 PRO A CD  1 
ATOM   2948 N N   . LEU A 1 599 ? 175.155 151.658 146.978 1.00 69.94  ? 599 LEU A N   1 
ATOM   2949 C CA  . LEU A 1 599 ? 175.973 152.588 146.207 1.00 70.54  ? 599 LEU A CA  1 
ATOM   2950 C C   . LEU A 1 599 ? 176.857 151.850 145.211 1.00 68.80  ? 599 LEU A C   1 
ATOM   2951 O O   . LEU A 1 599 ? 177.009 152.284 144.065 1.00 65.55  ? 599 LEU A O   1 
ATOM   2952 C CB  . LEU A 1 599 ? 176.815 153.445 147.148 1.00 73.23  ? 599 LEU A CB  1 
ATOM   2953 C CG  . LEU A 1 599 ? 176.043 154.421 148.034 1.00 78.06  ? 599 LEU A CG  1 
ATOM   2954 C CD1 . LEU A 1 599 ? 176.985 155.135 148.981 1.00 84.63  ? 599 LEU A CD1 1 
ATOM   2955 C CD2 . LEU A 1 599 ? 175.286 155.421 147.177 1.00 74.03  ? 599 LEU A CD2 1 
ATOM   2956 N N   . GLU A 1 600 ? 177.452 150.731 145.626 1.00 69.45  ? 600 GLU A N   1 
ATOM   2957 C CA  . GLU A 1 600 ? 178.236 149.938 144.687 1.00 66.98  ? 600 GLU A CA  1 
ATOM   2958 C C   . GLU A 1 600 ? 177.354 149.297 143.625 1.00 64.53  ? 600 GLU A C   1 
ATOM   2959 O O   . GLU A 1 600 ? 177.763 149.187 142.463 1.00 64.30  ? 600 GLU A O   1 
ATOM   2960 C CB  . GLU A 1 600 ? 179.043 148.877 145.432 1.00 68.04  ? 600 GLU A CB  1 
ATOM   2961 C CG  . GLU A 1 600 ? 179.720 147.854 144.534 1.00 69.66  ? 600 GLU A CG  1 
ATOM   2962 C CD  . GLU A 1 600 ? 180.611 148.474 143.470 1.00 72.17  ? 600 GLU A CD  1 
ATOM   2963 O OE1 . GLU A 1 600 ? 181.094 149.610 143.661 1.00 72.47  ? 600 GLU A OE1 1 
ATOM   2964 O OE2 . GLU A 1 600 ? 180.832 147.818 142.432 1.00 69.71  ? 600 GLU A OE2 1 
ATOM   2965 N N   . VAL A 1 601 ? 176.145 148.872 143.996 1.00 61.93  ? 601 VAL A N   1 
ATOM   2966 C CA  . VAL A 1 601 ? 175.212 148.390 142.983 1.00 56.77  ? 601 VAL A CA  1 
ATOM   2967 C C   . VAL A 1 601 ? 174.896 149.493 141.982 1.00 59.70  ? 601 VAL A C   1 
ATOM   2968 O O   . VAL A 1 601 ? 174.781 149.236 140.780 1.00 59.91  ? 601 VAL A O   1 
ATOM   2969 C CB  . VAL A 1 601 ? 173.938 147.838 143.644 1.00 51.19  ? 601 VAL A CB  1 
ATOM   2970 C CG1 . VAL A 1 601 ? 172.965 147.377 142.592 1.00 52.81  ? 601 VAL A CG1 1 
ATOM   2971 C CG2 . VAL A 1 601 ? 174.285 146.696 144.568 1.00 53.14  ? 601 VAL A CG2 1 
ATOM   2972 N N   . PHE A 1 602 ? 174.765 150.735 142.451 1.00 56.63  ? 602 PHE A N   1 
ATOM   2973 C CA  . PHE A 1 602 ? 174.560 151.863 141.547 1.00 50.91  ? 602 PHE A CA  1 
ATOM   2974 C C   . PHE A 1 602 ? 175.770 152.088 140.653 1.00 52.94  ? 602 PHE A C   1 
ATOM   2975 O O   . PHE A 1 602 ? 175.620 152.434 139.474 1.00 55.43  ? 602 PHE A O   1 
ATOM   2976 C CB  . PHE A 1 602 ? 174.260 153.134 142.342 1.00 52.16  ? 602 PHE A CB  1 
ATOM   2977 C CG  . PHE A 1 602 ? 173.900 154.315 141.485 1.00 49.23  ? 602 PHE A CG  1 
ATOM   2978 C CD1 . PHE A 1 602 ? 172.581 154.601 141.201 1.00 45.60  ? 602 PHE A CD1 1 
ATOM   2979 C CD2 . PHE A 1 602 ? 174.882 155.140 140.968 1.00 49.06  ? 602 PHE A CD2 1 
ATOM   2980 C CE1 . PHE A 1 602 ? 172.249 155.683 140.414 1.00 49.58  ? 602 PHE A CE1 1 
ATOM   2981 C CE2 . PHE A 1 602 ? 174.556 156.220 140.179 1.00 51.12  ? 602 PHE A CE2 1 
ATOM   2982 C CZ  . PHE A 1 602 ? 173.240 156.493 139.904 1.00 53.96  ? 602 PHE A CZ  1 
ATOM   2983 N N   . ARG A 1 603 ? 176.974 151.940 141.205 1.00 52.50  ? 603 ARG A N   1 
ATOM   2984 C CA  . ARG A 1 603 ? 178.170 152.090 140.385 1.00 55.89  ? 603 ARG A CA  1 
ATOM   2985 C C   . ARG A 1 603 ? 178.188 151.055 139.273 1.00 53.44  ? 603 ARG A C   1 
ATOM   2986 O O   . ARG A 1 603 ? 178.503 151.369 138.121 1.00 48.74  ? 603 ARG A O   1 
ATOM   2987 C CB  . ARG A 1 603 ? 179.430 151.967 141.235 1.00 61.38  ? 603 ARG A CB  1 
ATOM   2988 C CG  . ARG A 1 603 ? 180.693 152.268 140.446 1.00 64.92  ? 603 ARG A CG  1 
ATOM   2989 C CD  . ARG A 1 603 ? 181.934 151.730 141.120 1.00 65.93  ? 603 ARG A CD  1 
ATOM   2990 N NE  . ARG A 1 603 ? 181.898 150.279 141.236 1.00 68.04  ? 603 ARG A NE  1 
ATOM   2991 C CZ  . ARG A 1 603 ? 182.124 149.443 140.233 1.00 67.72  ? 603 ARG A CZ  1 
ATOM   2992 N NH1 . ARG A 1 603 ? 182.399 149.881 139.016 1.00 59.73  ? 603 ARG A NH1 1 
ATOM   2993 N NH2 . ARG A 1 603 ? 182.066 148.133 140.456 1.00 71.70  ? 603 ARG A NH2 1 
ATOM   2994 N N   . ARG A 1 604 ? 177.842 149.815 139.599 1.00 54.03  ? 604 ARG A N   1 
ATOM   2995 C CA  . ARG A 1 604 ? 177.725 148.784 138.580 1.00 48.72  ? 604 ARG A CA  1 
ATOM   2996 C C   . ARG A 1 604 ? 176.604 149.070 137.594 1.00 50.09  ? 604 ARG A C   1 
ATOM   2997 O O   . ARG A 1 604 ? 176.737 148.730 136.415 1.00 51.90  ? 604 ARG A O   1 
ATOM   2998 C CB  . ARG A 1 604 ? 177.512 147.425 139.236 1.00 44.91  ? 604 ARG A CB  1 
ATOM   2999 C CG  . ARG A 1 604 ? 177.459 146.280 138.258 1.00 43.01  ? 604 ARG A CG  1 
ATOM   3000 C CD  . ARG A 1 604 ? 178.664 146.275 137.347 1.00 46.64  ? 604 ARG A CD  1 
ATOM   3001 N NE  . ARG A 1 604 ? 179.905 146.191 138.102 1.00 53.20  ? 604 ARG A NE  1 
ATOM   3002 C CZ  . ARG A 1 604 ? 181.098 146.003 137.558 1.00 55.54  ? 604 ARG A CZ  1 
ATOM   3003 N NH1 . ARG A 1 604 ? 181.247 145.861 136.253 1.00 52.56  ? 604 ARG A NH1 1 
ATOM   3004 N NH2 . ARG A 1 604 ? 182.167 145.953 138.346 1.00 59.08  ? 604 ARG A NH2 1 
ATOM   3005 N N   . PHE A 1 605 ? 175.510 149.685 138.046 1.00 51.36  ? 605 PHE A N   1 
ATOM   3006 C CA  . PHE A 1 605 ? 174.439 150.091 137.143 1.00 48.90  ? 605 PHE A CA  1 
ATOM   3007 C C   . PHE A 1 605 ? 174.929 151.099 136.116 1.00 51.83  ? 605 PHE A C   1 
ATOM   3008 O O   . PHE A 1 605 ? 174.655 150.953 134.920 1.00 52.90  ? 605 PHE A O   1 
ATOM   3009 C CB  . PHE A 1 605 ? 173.274 150.676 137.944 1.00 45.13  ? 605 PHE A CB  1 
ATOM   3010 C CG  . PHE A 1 605 ? 172.511 151.754 137.221 1.00 43.15  ? 605 PHE A CG  1 
ATOM   3011 C CD1 . PHE A 1 605 ? 171.704 151.454 136.144 1.00 38.14  ? 605 PHE A CD1 1 
ATOM   3012 C CD2 . PHE A 1 605 ? 172.586 153.067 137.641 1.00 48.21  ? 605 PHE A CD2 1 
ATOM   3013 C CE1 . PHE A 1 605 ? 171.007 152.447 135.493 1.00 37.53  ? 605 PHE A CE1 1 
ATOM   3014 C CE2 . PHE A 1 605 ? 171.887 154.059 136.992 1.00 41.12  ? 605 PHE A CE2 1 
ATOM   3015 C CZ  . PHE A 1 605 ? 171.099 153.748 135.919 1.00 34.31  ? 605 PHE A CZ  1 
ATOM   3016 N N   . VAL A 1 606 ? 175.659 152.120 136.559 1.00 50.84  ? 606 VAL A N   1 
ATOM   3017 C CA  . VAL A 1 606 ? 176.166 153.120 135.627 1.00 47.45  ? 606 VAL A CA  1 
ATOM   3018 C C   . VAL A 1 606 ? 177.341 152.595 134.807 1.00 51.38  ? 606 VAL A C   1 
ATOM   3019 O O   . VAL A 1 606 ? 177.622 153.132 133.727 1.00 54.00  ? 606 VAL A O   1 
ATOM   3020 C CB  . VAL A 1 606 ? 176.558 154.410 136.367 1.00 49.16  ? 606 VAL A CB  1 
ATOM   3021 C CG1 . VAL A 1 606 ? 177.893 154.245 137.058 1.00 50.08  ? 606 VAL A CG1 1 
ATOM   3022 C CG2 . VAL A 1 606 ? 176.584 155.584 135.407 1.00 62.15  ? 606 VAL A CG2 1 
ATOM   3023 N N   . TRP A 1 607 ? 178.027 151.555 135.285 1.00 50.54  ? 607 TRP A N   1 
ATOM   3024 C CA  . TRP A 1 607 ? 179.098 150.944 134.507 1.00 48.78  ? 607 TRP A CA  1 
ATOM   3025 C C   . TRP A 1 607 ? 178.560 150.311 133.233 1.00 49.87  ? 607 TRP A C   1 
ATOM   3026 O O   . TRP A 1 607 ? 179.200 150.388 132.177 1.00 50.89  ? 607 TRP A O   1 
ATOM   3027 C CB  . TRP A 1 607 ? 179.824 149.910 135.367 1.00 49.32  ? 607 TRP A CB  1 
ATOM   3028 C CG  . TRP A 1 607 ? 180.908 149.162 134.668 1.00 50.82  ? 607 TRP A CG  1 
ATOM   3029 C CD1 . TRP A 1 607 ? 182.213 149.525 134.563 1.00 54.02  ? 607 TRP A CD1 1 
ATOM   3030 C CD2 . TRP A 1 607 ? 180.784 147.905 133.993 1.00 51.16  ? 607 TRP A CD2 1 
ATOM   3031 N NE1 . TRP A 1 607 ? 182.911 148.580 133.853 1.00 58.79  ? 607 TRP A NE1 1 
ATOM   3032 C CE2 . TRP A 1 607 ? 182.054 147.573 133.494 1.00 56.48  ? 607 TRP A CE2 1 
ATOM   3033 C CE3 . TRP A 1 607 ? 179.721 147.028 133.761 1.00 49.93  ? 607 TRP A CE3 1 
ATOM   3034 C CZ2 . TRP A 1 607 ? 182.289 146.407 132.775 1.00 55.48  ? 607 TRP A CZ2 1 
ATOM   3035 C CZ3 . TRP A 1 607 ? 179.959 145.872 133.050 1.00 45.32  ? 607 TRP A CZ3 1 
ATOM   3036 C CH2 . TRP A 1 607 ? 181.231 145.571 132.568 1.00 48.76  ? 607 TRP A CH2 1 
ATOM   3037 N N   . ASN A 1 608 ? 177.388 149.676 133.315 1.00 49.70  ? 608 ASN A N   1 
ATOM   3038 C CA  . ASN A 1 608 ? 176.810 149.010 132.152 1.00 50.41  ? 608 ASN A CA  1 
ATOM   3039 C C   . ASN A 1 608 ? 176.511 150.001 131.039 1.00 52.12  ? 608 ASN A C   1 
ATOM   3040 O O   . ASN A 1 608 ? 176.747 149.711 129.858 1.00 55.53  ? 608 ASN A O   1 
ATOM   3041 C CB  . ASN A 1 608 ? 175.532 148.278 132.545 1.00 45.23  ? 608 ASN A CB  1 
ATOM   3042 C CG  . ASN A 1 608 ? 175.748 147.287 133.650 1.00 45.50  ? 608 ASN A CG  1 
ATOM   3043 O OD1 . ASN A 1 608 ? 176.142 146.150 133.405 1.00 50.22  ? 608 ASN A OD1 1 
ATOM   3044 N ND2 . ASN A 1 608 ? 175.481 147.703 134.879 1.00 47.05  ? 608 ASN A ND2 1 
ATOM   3045 N N   . PHE A 1 609 ? 175.986 151.173 131.403 1.00 46.02  ? 609 PHE A N   1 
ATOM   3046 C CA  . PHE A 1 609 ? 175.545 152.151 130.415 1.00 47.96  ? 609 PHE A CA  1 
ATOM   3047 C C   . PHE A 1 609 ? 176.647 152.484 129.427 1.00 55.55  ? 609 PHE A C   1 
ATOM   3048 O O   . PHE A 1 609 ? 176.386 152.695 128.238 1.00 57.97  ? 609 PHE A O   1 
ATOM   3049 C CB  . PHE A 1 609 ? 175.076 153.419 131.121 1.00 46.51  ? 609 PHE A CB  1 
ATOM   3050 C CG  . PHE A 1 609 ? 173.600 153.495 131.297 1.00 42.60  ? 609 PHE A CG  1 
ATOM   3051 C CD1 . PHE A 1 609 ? 172.755 153.033 130.312 1.00 47.19  ? 609 PHE A CD1 1 
ATOM   3052 C CD2 . PHE A 1 609 ? 173.055 154.023 132.445 1.00 37.34  ? 609 PHE A CD2 1 
ATOM   3053 C CE1 . PHE A 1 609 ? 171.394 153.101 130.467 1.00 47.25  ? 609 PHE A CE1 1 
ATOM   3054 C CE2 . PHE A 1 609 ? 171.696 154.090 132.604 1.00 34.01  ? 609 PHE A CE2 1 
ATOM   3055 C CZ  . PHE A 1 609 ? 170.863 153.631 131.614 1.00 39.88  ? 609 PHE A CZ  1 
ATOM   3056 N N   . PHE A 1 610 ? 177.886 152.533 129.900 1.00 58.00  ? 610 PHE A N   1 
ATOM   3057 C CA  . PHE A 1 610 ? 179.002 152.875 129.036 1.00 55.27  ? 610 PHE A CA  1 
ATOM   3058 C C   . PHE A 1 610 ? 179.762 151.654 128.553 1.00 55.54  ? 610 PHE A C   1 
ATOM   3059 O O   . PHE A 1 610 ? 180.338 151.696 127.463 1.00 59.75  ? 610 PHE A O   1 
ATOM   3060 C CB  . PHE A 1 610 ? 179.940 153.839 129.760 1.00 55.65  ? 610 PHE A CB  1 
ATOM   3061 C CG  . PHE A 1 610 ? 179.235 155.030 130.333 1.00 61.50  ? 610 PHE A CG  1 
ATOM   3062 C CD1 . PHE A 1 610 ? 178.803 156.053 129.510 1.00 62.63  ? 610 PHE A CD1 1 
ATOM   3063 C CD2 . PHE A 1 610 ? 178.982 155.115 131.688 1.00 63.35  ? 610 PHE A CD2 1 
ATOM   3064 C CE1 . PHE A 1 610 ? 178.143 157.143 130.032 1.00 71.13  ? 610 PHE A CE1 1 
ATOM   3065 C CE2 . PHE A 1 610 ? 178.324 156.202 132.214 1.00 62.35  ? 610 PHE A CE2 1 
ATOM   3066 C CZ  . PHE A 1 610 ? 177.904 157.217 131.386 1.00 70.22  ? 610 PHE A CZ  1 
ATOM   3067 N N   . ARG A 1 611 ? 179.767 150.555 129.311 1.00 55.54  ? 611 ARG A N   1 
ATOM   3068 C CA  . ARG A 1 611 ? 180.433 149.354 128.824 1.00 54.47  ? 611 ARG A CA  1 
ATOM   3069 C C   . ARG A 1 611 ? 179.732 148.802 127.592 1.00 58.20  ? 611 ARG A C   1 
ATOM   3070 O O   . ARG A 1 611 ? 180.385 148.443 126.605 1.00 61.35  ? 611 ARG A O   1 
ATOM   3071 C CB  . ARG A 1 611 ? 180.499 148.293 129.915 1.00 51.88  ? 611 ARG A CB  1 
ATOM   3072 C CG  . ARG A 1 611 ? 181.135 147.012 129.433 1.00 52.55  ? 611 ARG A CG  1 
ATOM   3073 C CD  . ARG A 1 611 ? 182.477 147.298 128.796 1.00 56.76  ? 611 ARG A CD  1 
ATOM   3074 N NE  . ARG A 1 611 ? 182.945 146.207 127.952 1.00 67.55  ? 611 ARG A NE  1 
ATOM   3075 C CZ  . ARG A 1 611 ? 183.908 145.361 128.283 1.00 71.72  ? 611 ARG A CZ  1 
ATOM   3076 N NH1 . ARG A 1 611 ? 184.529 145.443 129.447 1.00 67.31  ? 611 ARG A NH1 1 
ATOM   3077 N NH2 . ARG A 1 611 ? 184.263 144.414 127.421 1.00 73.15  ? 611 ARG A NH2 1 
ATOM   3078 N N   . LEU A 1 612 ? 178.401 148.731 127.624 1.00 62.07  ? 612 LEU A N   1 
ATOM   3079 C CA  . LEU A 1 612 ? 177.676 148.244 126.454 1.00 66.29  ? 612 LEU A CA  1 
ATOM   3080 C C   . LEU A 1 612 ? 177.792 149.219 125.288 1.00 64.41  ? 612 LEU A C   1 
ATOM   3081 O O   . LEU A 1 612 ? 177.841 148.801 124.126 1.00 59.95  ? 612 LEU A O   1 
ATOM   3082 C CB  . LEU A 1 612 ? 176.211 147.983 126.805 1.00 62.29  ? 612 LEU A CB  1 
ATOM   3083 C CG  . LEU A 1 612 ? 175.891 146.625 127.434 1.00 54.28  ? 612 LEU A CG  1 
ATOM   3084 C CD1 . LEU A 1 612 ? 176.448 145.510 126.573 1.00 52.00  ? 612 LEU A CD1 1 
ATOM   3085 C CD2 . LEU A 1 612 ? 176.416 146.528 128.858 1.00 52.56  ? 612 LEU A CD2 1 
ATOM   3086 N N   . GLU A 1 613 ? 177.836 150.520 125.577 1.00 61.17  ? 613 GLU A N   1 
ATOM   3087 C CA  . GLU A 1 613 ? 178.049 151.505 124.523 1.00 61.47  ? 613 GLU A CA  1 
ATOM   3088 C C   . GLU A 1 613 ? 179.407 151.313 123.864 1.00 64.64  ? 613 GLU A C   1 
ATOM   3089 O O   . GLU A 1 613 ? 179.533 151.377 122.636 1.00 74.42  ? 613 GLU A O   1 
ATOM   3090 C CB  . GLU A 1 613 ? 177.926 152.914 125.099 1.00 67.58  ? 613 GLU A CB  1 
ATOM   3091 C CG  . GLU A 1 613 ? 178.238 154.023 124.110 1.00 78.12  ? 613 GLU A CG  1 
ATOM   3092 C CD  . GLU A 1 613 ? 178.599 155.325 124.796 1.00 81.74  ? 613 GLU A CD  1 
ATOM   3093 O OE1 . GLU A 1 613 ? 178.792 155.315 126.030 1.00 78.90  ? 613 GLU A OE1 1 
ATOM   3094 O OE2 . GLU A 1 613 ? 178.695 156.359 124.103 1.00 85.12  ? 613 GLU A OE2 1 
ATOM   3095 N N   . ASN A 1 614 ? 180.442 151.084 124.671 1.00 61.43  ? 614 ASN A N   1 
ATOM   3096 C CA  . ASN A 1 614 ? 181.773 150.850 124.126 1.00 65.61  ? 614 ASN A CA  1 
ATOM   3097 C C   . ASN A 1 614 ? 181.808 149.571 123.304 1.00 69.50  ? 614 ASN A C   1 
ATOM   3098 O O   . ASN A 1 614 ? 182.440 149.522 122.243 1.00 71.42  ? 614 ASN A O   1 
ATOM   3099 C CB  . ASN A 1 614 ? 182.794 150.787 125.259 1.00 67.16  ? 614 ASN A CB  1 
ATOM   3100 C CG  . ASN A 1 614 ? 184.208 150.637 124.756 1.00 68.51  ? 614 ASN A CG  1 
ATOM   3101 O OD1 . ASN A 1 614 ? 184.661 149.533 124.469 1.00 67.97  ? 614 ASN A OD1 1 
ATOM   3102 N ND2 . ASN A 1 614 ? 184.918 151.750 124.648 1.00 64.22  ? 614 ASN A ND2 1 
ATOM   3103 N N   . GLU A 1 615 ? 181.138 148.522 123.784 1.00 68.71  ? 615 GLU A N   1 
ATOM   3104 C CA  . GLU A 1 615 ? 181.093 147.271 123.037 1.00 66.98  ? 615 GLU A CA  1 
ATOM   3105 C C   . GLU A 1 615 ? 180.349 147.430 121.718 1.00 70.44  ? 615 GLU A C   1 
ATOM   3106 O O   . GLU A 1 615 ? 180.730 146.821 120.711 1.00 72.09  ? 615 GLU A O   1 
ATOM   3107 C CB  . GLU A 1 615 ? 180.450 146.179 123.886 1.00 62.65  ? 615 GLU A CB  1 
ATOM   3108 C CG  . GLU A 1 615 ? 180.042 144.945 123.105 1.00 67.88  ? 615 GLU A CG  1 
ATOM   3109 C CD  . GLU A 1 615 ? 181.218 144.138 122.594 1.00 71.05  ? 615 GLU A CD  1 
ATOM   3110 O OE1 . GLU A 1 615 ? 182.360 144.412 123.011 1.00 75.76  ? 615 GLU A OE1 1 
ATOM   3111 O OE2 . GLU A 1 615 ? 180.999 143.220 121.776 1.00 67.05  ? 615 GLU A OE2 1 
ATOM   3112 N N   . HIS A 1 616 ? 179.292 148.239 121.701 1.00 69.95  ? 616 HIS A N   1 
ATOM   3113 C CA  . HIS A 1 616 ? 178.537 148.457 120.472 1.00 69.86  ? 616 HIS A CA  1 
ATOM   3114 C C   . HIS A 1 616 ? 179.399 149.117 119.403 1.00 72.70  ? 616 HIS A C   1 
ATOM   3115 O O   . HIS A 1 616 ? 179.350 148.735 118.229 1.00 74.14  ? 616 HIS A O   1 
ATOM   3116 C CB  . HIS A 1 616 ? 177.299 149.302 120.773 1.00 67.18  ? 616 HIS A CB  1 
ATOM   3117 C CG  . HIS A 1 616 ? 176.580 149.780 119.552 1.00 70.19  ? 616 HIS A CG  1 
ATOM   3118 N ND1 . HIS A 1 616 ? 176.423 151.116 119.257 1.00 74.07  ? 616 HIS A ND1 1 
ATOM   3119 C CD2 . HIS A 1 616 ? 175.973 149.100 118.550 1.00 71.88  ? 616 HIS A CD2 1 
ATOM   3120 C CE1 . HIS A 1 616 ? 175.750 151.239 118.127 1.00 77.84  ? 616 HIS A CE1 1 
ATOM   3121 N NE2 . HIS A 1 616 ? 175.466 150.031 117.678 1.00 77.44  ? 616 HIS A NE2 1 
ATOM   3122 N N   . LEU A 1 617 ? 180.206 150.102 119.792 1.00 72.34  ? 617 LEU A N   1 
ATOM   3123 C CA  . LEU A 1 617 ? 180.978 150.876 118.829 1.00 74.46  ? 617 LEU A CA  1 
ATOM   3124 C C   . LEU A 1 617 ? 182.382 150.319 118.639 1.00 81.81  ? 617 LEU A C   1 
ATOM   3125 O O   . LEU A 1 617 ? 182.756 149.926 117.529 1.00 88.48  ? 617 LEU A O   1 
ATOM   3126 C CB  . LEU A 1 617 ? 181.054 152.337 119.275 1.00 77.12  ? 617 LEU A CB  1 
ATOM   3127 C CG  . LEU A 1 617 ? 179.711 153.041 119.465 1.00 78.78  ? 617 LEU A CG  1 
ATOM   3128 C CD1 . LEU A 1 617 ? 179.893 154.390 120.131 1.00 75.21  ? 617 LEU A CD1 1 
ATOM   3129 C CD2 . LEU A 1 617 ? 179.007 153.197 118.129 1.00 86.81  ? 617 LEU A CD2 1 
ATOM   3130 N N   . ASN A 1 618 ? 183.167 150.277 119.717 1.00 79.12  ? 618 ASN A N   1 
ATOM   3131 C CA  . ASN A 1 618 ? 184.571 149.900 119.619 1.00 76.92  ? 618 ASN A CA  1 
ATOM   3132 C C   . ASN A 1 618 ? 184.756 148.401 119.411 1.00 77.59  ? 618 ASN A C   1 
ATOM   3133 O O   . ASN A 1 618 ? 185.777 147.959 118.872 1.00 80.55  ? 618 ASN A O   1 
ATOM   3134 C CB  . ASN A 1 618 ? 185.317 150.363 120.875 1.00 75.75  ? 618 ASN A CB  1 
ATOM   3135 C CG  . ASN A 1 618 ? 185.462 151.870 120.943 1.00 82.09  ? 618 ASN A CG  1 
ATOM   3136 O OD1 . ASN A 1 618 ? 184.758 152.605 120.253 1.00 85.33  ? 618 ASN A OD1 1 
ATOM   3137 N ND2 . ASN A 1 618 ? 186.382 152.337 121.779 1.00 78.06  ? 618 ASN A ND2 1 
ATOM   3138 N N   . ASN A 1 619 ? 183.774 147.611 119.846 1.00 77.63  ? 619 ASN A N   1 
ATOM   3139 C CA  . ASN A 1 619 ? 183.848 146.153 119.821 1.00 75.85  ? 619 ASN A CA  1 
ATOM   3140 C C   . ASN A 1 619 ? 184.996 145.671 120.700 1.00 74.01  ? 619 ASN A C   1 
ATOM   3141 O O   . ASN A 1 619 ? 185.599 144.627 120.432 1.00 75.86  ? 619 ASN A O   1 
ATOM   3142 C CB  . ASN A 1 619 ? 183.998 145.635 118.387 1.00 81.87  ? 619 ASN A CB  1 
ATOM   3143 C CG  . ASN A 1 619 ? 183.615 144.178 118.248 1.00 82.22  ? 619 ASN A CG  1 
ATOM   3144 O OD1 . ASN A 1 619 ? 182.510 143.854 117.812 1.00 73.89  ? 619 ASN A OD1 1 
ATOM   3145 N ND2 . ASN A 1 619 ? 184.528 143.289 118.617 1.00 85.35  ? 619 ASN A ND2 1 
ATOM   3146 N N   . CYS A 1 620 ? 185.299 146.430 121.752 1.00 38.71  ? 620 CYS A N   1 
ATOM   3147 C CA  . CYS A 1 620 ? 186.383 146.093 122.665 1.00 38.39  ? 620 CYS A CA  1 
ATOM   3148 C C   . CYS A 1 620 ? 186.117 144.774 123.373 1.00 39.64  ? 620 CYS A C   1 
ATOM   3149 O O   . CYS A 1 620 ? 184.981 144.471 123.744 1.00 38.40  ? 620 CYS A O   1 
ATOM   3150 C CB  . CYS A 1 620 ? 186.559 147.206 123.695 1.00 42.23  ? 620 CYS A CB  1 
ATOM   3151 S SG  . CYS A 1 620 ? 187.748 146.831 124.999 1.00 66.50  ? 620 CYS A SG  1 
ATOM   3152 N N   . GLY A 1 621 ? 187.179 144.000 123.576 1.00 40.20  ? 621 GLY A N   1 
ATOM   3153 C CA  . GLY A 1 621 ? 187.090 142.701 124.209 1.00 41.85  ? 621 GLY A CA  1 
ATOM   3154 C C   . GLY A 1 621 ? 187.151 141.537 123.249 1.00 42.92  ? 621 GLY A C   1 
ATOM   3155 O O   . GLY A 1 621 ? 187.213 140.386 123.703 1.00 44.13  ? 621 GLY A O   1 
ATOM   3156 N N   . GLU A 1 622 ? 187.137 141.797 121.942 1.00 43.68  ? 622 GLU A N   1 
ATOM   3157 C CA  . GLU A 1 622 ? 187.204 140.758 120.921 1.00 44.76  ? 622 GLU A CA  1 
ATOM   3158 C C   . GLU A 1 622 ? 186.103 139.722 121.099 1.00 44.28  ? 622 GLU A C   1 
ATOM   3159 O O   . GLU A 1 622 ? 186.384 138.540 121.320 1.00 49.52  ? 622 GLU A O   1 
ATOM   3160 C CB  . GLU A 1 622 ? 188.574 140.079 120.932 1.00 45.95  ? 622 GLU A CB  1 
ATOM   3161 C CG  . GLU A 1 622 ? 189.723 140.997 120.557 1.00 48.23  ? 622 GLU A CG  1 
ATOM   3162 C CD  . GLU A 1 622 ? 191.022 140.244 120.342 1.00 56.33  ? 622 GLU A CD  1 
ATOM   3163 O OE1 . GLU A 1 622 ? 191.094 139.057 120.727 1.00 52.26  ? 622 GLU A OE1 1 
ATOM   3164 O OE2 . GLU A 1 622 ? 191.970 140.836 119.784 1.00 56.71  ? 622 GLU A OE2 1 
ATOM   3165 N N   . PHE A 1 623 ? 184.847 140.156 121.011 1.00 38.12  ? 623 PHE A N   1 
ATOM   3166 C CA  . PHE A 1 623 ? 183.718 139.242 121.026 1.00 33.82  ? 623 PHE A CA  1 
ATOM   3167 C C   . PHE A 1 623 ? 182.969 139.183 119.705 1.00 38.32  ? 623 PHE A C   1 
ATOM   3168 O O   . PHE A 1 623 ? 182.239 138.211 119.478 1.00 40.94  ? 623 PHE A O   1 
ATOM   3169 C CB  . PHE A 1 623 ? 182.728 139.622 122.136 1.00 35.02  ? 623 PHE A CB  1 
ATOM   3170 C CG  . PHE A 1 623 ? 183.244 139.375 123.525 1.00 37.06  ? 623 PHE A CG  1 
ATOM   3171 C CD1 . PHE A 1 623 ? 183.406 138.086 123.996 1.00 37.83  ? 623 PHE A CD1 1 
ATOM   3172 C CD2 . PHE A 1 623 ? 183.545 140.430 124.366 1.00 36.75  ? 623 PHE A CD2 1 
ATOM   3173 C CE1 . PHE A 1 623 ? 183.871 137.858 125.272 1.00 37.42  ? 623 PHE A CE1 1 
ATOM   3174 C CE2 . PHE A 1 623 ? 184.009 140.205 125.644 1.00 35.00  ? 623 PHE A CE2 1 
ATOM   3175 C CZ  . PHE A 1 623 ? 184.170 138.920 126.097 1.00 36.91  ? 623 PHE A CZ  1 
ATOM   3176 N N   . ARG A 1 624 ? 183.123 140.179 118.836 1.00 40.15  ? 624 ARG A N   1 
ATOM   3177 C CA  . ARG A 1 624 ? 182.440 140.242 117.545 1.00 43.81  ? 624 ARG A CA  1 
ATOM   3178 C C   . ARG A 1 624 ? 180.926 140.129 117.693 1.00 45.52  ? 624 ARG A C   1 
ATOM   3179 O O   . ARG A 1 624 ? 180.366 140.370 118.763 1.00 43.34  ? 624 ARG A O   1 
ATOM   3180 C CB  . ARG A 1 624 ? 182.960 139.152 116.603 1.00 42.93  ? 624 ARG A CB  1 
ATOM   3181 C CG  . ARG A 1 624 ? 184.451 139.240 116.323 1.00 45.62  ? 624 ARG A CG  1 
ATOM   3182 C CD  . ARG A 1 624 ? 184.804 138.607 114.988 1.00 49.70  ? 624 ARG A CD  1 
ATOM   3183 N NE  . ARG A 1 624 ? 184.176 139.312 113.877 1.00 53.88  ? 624 ARG A NE  1 
ATOM   3184 C CZ  . ARG A 1 624 ? 184.688 140.382 113.283 1.00 53.15  ? 624 ARG A CZ  1 
ATOM   3185 N NH1 . ARG A 1 624 ? 185.846 140.896 113.663 1.00 54.04  ? 624 ARG A NH1 1 
ATOM   3186 N NH2 . ARG A 1 624 ? 184.021 140.950 112.283 1.00 46.59  ? 624 ARG A NH2 1 
ATOM   3187 N N   . ALA B 1 229 ? 144.452 154.164 126.815 1.00 73.51  ? 229 ALA B N   1 
ATOM   3188 C CA  . ALA B 1 229 ? 145.234 153.604 125.718 1.00 76.52  ? 229 ALA B CA  1 
ATOM   3189 C C   . ALA B 1 229 ? 146.741 153.892 125.827 1.00 77.75  ? 229 ALA B C   1 
ATOM   3190 O O   . ALA B 1 229 ? 147.541 152.976 125.635 1.00 78.70  ? 229 ALA B O   1 
ATOM   3191 C CB  . ALA B 1 229 ? 144.690 154.098 124.371 1.00 78.15  ? 229 ALA B CB  1 
ATOM   3192 N N   . PRO B 1 230 ? 147.144 155.134 126.126 1.00 73.56  ? 230 PRO B N   1 
ATOM   3193 C CA  . PRO B 1 230 ? 148.577 155.404 126.276 1.00 72.10  ? 230 PRO B CA  1 
ATOM   3194 C C   . PRO B 1 230 ? 149.175 154.574 127.399 1.00 71.84  ? 230 PRO B C   1 
ATOM   3195 O O   . PRO B 1 230 ? 148.505 154.241 128.379 1.00 71.09  ? 230 PRO B O   1 
ATOM   3196 C CB  . PRO B 1 230 ? 148.629 156.901 126.598 1.00 66.91  ? 230 PRO B CB  1 
ATOM   3197 C CG  . PRO B 1 230 ? 147.393 157.444 126.020 1.00 67.86  ? 230 PRO B CG  1 
ATOM   3198 C CD  . PRO B 1 230 ? 146.366 156.383 126.241 1.00 67.53  ? 230 PRO B CD  1 
ATOM   3199 N N   . ALA B 1 231 ? 150.454 154.232 127.239 1.00 70.90  ? 231 ALA B N   1 
ATOM   3200 C CA  . ALA B 1 231 ? 151.112 153.366 128.211 1.00 70.63  ? 231 ALA B CA  1 
ATOM   3201 C C   . ALA B 1 231 ? 151.134 154.003 129.594 1.00 64.66  ? 231 ALA B C   1 
ATOM   3202 O O   . ALA B 1 231 ? 150.973 153.312 130.607 1.00 61.96  ? 231 ALA B O   1 
ATOM   3203 C CB  . ALA B 1 231 ? 152.529 153.039 127.745 1.00 69.47  ? 231 ALA B CB  1 
ATOM   3204 N N   . TRP B 1 232 ? 151.333 155.318 129.659 1.00 59.88  ? 232 TRP B N   1 
ATOM   3205 C CA  . TRP B 1 232 ? 151.371 155.980 130.956 1.00 57.73  ? 232 TRP B CA  1 
ATOM   3206 C C   . TRP B 1 232 ? 150.006 155.998 131.628 1.00 56.88  ? 232 TRP B C   1 
ATOM   3207 O O   . TRP B 1 232 ? 149.928 155.959 132.858 1.00 53.59  ? 232 TRP B O   1 
ATOM   3208 C CB  . TRP B 1 232 ? 151.922 157.394 130.807 1.00 58.63  ? 232 TRP B CB  1 
ATOM   3209 C CG  . TRP B 1 232 ? 153.406 157.423 130.837 1.00 61.78  ? 232 TRP B CG  1 
ATOM   3210 C CD1 . TRP B 1 232 ? 154.244 157.505 129.770 1.00 61.81  ? 232 TRP B CD1 1 
ATOM   3211 C CD2 . TRP B 1 232 ? 154.238 157.343 131.998 1.00 62.77  ? 232 TRP B CD2 1 
ATOM   3212 N NE1 . TRP B 1 232 ? 155.549 157.495 130.193 1.00 63.59  ? 232 TRP B NE1 1 
ATOM   3213 C CE2 . TRP B 1 232 ? 155.571 157.395 131.559 1.00 65.09  ? 232 TRP B CE2 1 
ATOM   3214 C CE3 . TRP B 1 232 ? 153.983 157.241 133.368 1.00 57.19  ? 232 TRP B CE3 1 
ATOM   3215 C CZ2 . TRP B 1 232 ? 156.647 157.348 132.438 1.00 65.96  ? 232 TRP B CZ2 1 
ATOM   3216 C CZ3 . TRP B 1 232 ? 155.051 157.194 134.238 1.00 56.25  ? 232 TRP B CZ3 1 
ATOM   3217 C CH2 . TRP B 1 232 ? 156.367 157.247 133.771 1.00 62.11  ? 232 TRP B CH2 1 
ATOM   3218 N N   . THR B 1 233 ? 148.922 156.056 130.853 1.00 61.40  ? 233 THR B N   1 
ATOM   3219 C CA  . THR B 1 233 ? 147.598 155.965 131.459 1.00 55.70  ? 233 THR B CA  1 
ATOM   3220 C C   . THR B 1 233 ? 147.379 154.597 132.087 1.00 53.49  ? 233 THR B C   1 
ATOM   3221 O O   . THR B 1 233 ? 146.840 154.496 133.192 1.00 54.88  ? 233 THR B O   1 
ATOM   3222 C CB  . THR B 1 233 ? 146.513 156.261 130.427 1.00 56.48  ? 233 THR B CB  1 
ATOM   3223 O OG1 . THR B 1 233 ? 146.666 157.602 129.946 1.00 64.92  ? 233 THR B OG1 1 
ATOM   3224 C CG2 . THR B 1 233 ? 145.142 156.116 131.051 1.00 52.75  ? 233 THR B CG2 1 
ATOM   3225 N N   . THR B 1 234 ? 147.799 153.530 131.402 1.00 53.34  ? 234 THR B N   1 
ATOM   3226 C CA  . THR B 1 234 ? 147.691 152.196 131.983 1.00 49.25  ? 234 THR B CA  1 
ATOM   3227 C C   . THR B 1 234 ? 148.570 152.063 133.219 1.00 51.69  ? 234 THR B C   1 
ATOM   3228 O O   . THR B 1 234 ? 148.172 151.441 134.212 1.00 51.14  ? 234 THR B O   1 
ATOM   3229 C CB  . THR B 1 234 ? 148.061 151.137 130.949 1.00 46.40  ? 234 THR B CB  1 
ATOM   3230 O OG1 . THR B 1 234 ? 147.341 151.383 129.738 1.00 58.83  ? 234 THR B OG1 1 
ATOM   3231 C CG2 . THR B 1 234 ? 147.700 149.760 131.456 1.00 45.82  ? 234 THR B CG2 1 
ATOM   3232 N N   . PHE B 1 235 ? 149.771 152.647 133.179 1.00 56.04  ? 235 PHE B N   1 
ATOM   3233 C CA  . PHE B 1 235 ? 150.630 152.631 134.357 1.00 54.91  ? 235 PHE B CA  1 
ATOM   3234 C C   . PHE B 1 235 ? 149.978 153.356 135.526 1.00 52.85  ? 235 PHE B C   1 
ATOM   3235 O O   . PHE B 1 235 ? 150.041 152.884 136.664 1.00 52.99  ? 235 PHE B O   1 
ATOM   3236 C CB  . PHE B 1 235 ? 151.988 153.255 134.039 1.00 51.17  ? 235 PHE B CB  1 
ATOM   3237 C CG  . PHE B 1 235 ? 152.825 153.528 135.258 1.00 48.52  ? 235 PHE B CG  1 
ATOM   3238 C CD1 . PHE B 1 235 ? 153.528 152.511 135.872 1.00 46.70  ? 235 PHE B CD1 1 
ATOM   3239 C CD2 . PHE B 1 235 ? 152.905 154.801 135.791 1.00 50.29  ? 235 PHE B CD2 1 
ATOM   3240 C CE1 . PHE B 1 235 ? 154.288 152.757 136.991 1.00 46.58  ? 235 PHE B CE1 1 
ATOM   3241 C CE2 . PHE B 1 235 ? 153.665 155.049 136.910 1.00 52.43  ? 235 PHE B CE2 1 
ATOM   3242 C CZ  . PHE B 1 235 ? 154.356 154.026 137.510 1.00 50.55  ? 235 PHE B CZ  1 
ATOM   3243 N N   . ARG B 1 236 ? 149.362 154.512 135.271 1.00 50.21  ? 236 ARG B N   1 
ATOM   3244 C CA  . ARG B 1 236 ? 148.684 155.235 136.341 1.00 47.46  ? 236 ARG B CA  1 
ATOM   3245 C C   . ARG B 1 236 ? 147.490 154.451 136.861 1.00 49.22  ? 236 ARG B C   1 
ATOM   3246 O O   . ARG B 1 236 ? 147.216 154.455 138.065 1.00 54.41  ? 236 ARG B O   1 
ATOM   3247 C CB  . ARG B 1 236 ? 148.247 156.618 135.862 1.00 50.43  ? 236 ARG B CB  1 
ATOM   3248 C CG  . ARG B 1 236 ? 149.341 157.666 135.889 1.00 50.23  ? 236 ARG B CG  1 
ATOM   3249 C CD  . ARG B 1 236 ? 148.778 159.054 135.674 1.00 46.55  ? 236 ARG B CD  1 
ATOM   3250 N NE  . ARG B 1 236 ? 148.021 159.137 134.434 1.00 50.92  ? 236 ARG B NE  1 
ATOM   3251 C CZ  . ARG B 1 236 ? 148.551 159.398 133.249 1.00 55.65  ? 236 ARG B CZ  1 
ATOM   3252 N NH1 . ARG B 1 236 ? 149.845 159.618 133.108 1.00 57.79  ? 236 ARG B NH1 1 
ATOM   3253 N NH2 . ARG B 1 236 ? 147.764 159.434 132.180 1.00 56.61  ? 236 ARG B NH2 1 
ATOM   3254 N N   . VAL B 1 237 ? 146.766 153.773 135.969 1.00 47.67  ? 237 VAL B N   1 
ATOM   3255 C CA  . VAL B 1 237 ? 145.662 152.920 136.402 1.00 47.67  ? 237 VAL B CA  1 
ATOM   3256 C C   . VAL B 1 237 ? 146.165 151.859 137.368 1.00 53.15  ? 237 VAL B C   1 
ATOM   3257 O O   . VAL B 1 237 ? 145.623 151.684 138.465 1.00 55.52  ? 237 VAL B O   1 
ATOM   3258 C CB  . VAL B 1 237 ? 144.967 152.284 135.187 1.00 45.13  ? 237 VAL B CB  1 
ATOM   3259 C CG1 . VAL B 1 237 ? 144.124 151.106 135.620 1.00 41.26  ? 237 VAL B CG1 1 
ATOM   3260 C CG2 . VAL B 1 237 ? 144.116 153.306 134.486 1.00 50.37  ? 237 VAL B CG2 1 
ATOM   3261 N N   . GLY B 1 238 ? 147.232 151.156 136.986 1.00 50.75  ? 238 GLY B N   1 
ATOM   3262 C CA  . GLY B 1 238 ? 147.782 150.132 137.861 1.00 51.22  ? 238 GLY B CA  1 
ATOM   3263 C C   . GLY B 1 238 ? 148.308 150.693 139.168 1.00 52.20  ? 238 GLY B C   1 
ATOM   3264 O O   . GLY B 1 238 ? 148.093 150.114 140.235 1.00 50.47  ? 238 GLY B O   1 
ATOM   3265 N N   . LEU B 1 239 ? 149.009 151.824 139.100 1.00 51.10  ? 239 LEU B N   1 
ATOM   3266 C CA  . LEU B 1 239 ? 149.577 152.439 140.293 1.00 49.32  ? 239 LEU B CA  1 
ATOM   3267 C C   . LEU B 1 239 ? 148.486 152.833 141.277 1.00 46.85  ? 239 LEU B C   1 
ATOM   3268 O O   . LEU B 1 239 ? 148.578 152.544 142.476 1.00 48.34  ? 239 LEU B O   1 
ATOM   3269 C CB  . LEU B 1 239 ? 150.406 153.655 139.883 1.00 47.62  ? 239 LEU B CB  1 
ATOM   3270 C CG  . LEU B 1 239 ? 150.864 154.670 140.922 1.00 45.70  ? 239 LEU B CG  1 
ATOM   3271 C CD1 . LEU B 1 239 ? 152.042 154.142 141.703 1.00 48.13  ? 239 LEU B CD1 1 
ATOM   3272 C CD2 . LEU B 1 239 ? 151.215 155.970 140.227 1.00 49.95  ? 239 LEU B CD2 1 
ATOM   3273 N N   . PHE B 1 240 ? 147.436 153.488 140.781 1.00 45.98  ? 240 PHE B N   1 
ATOM   3274 C CA  . PHE B 1 240 ? 146.347 153.910 141.649 1.00 44.96  ? 240 PHE B CA  1 
ATOM   3275 C C   . PHE B 1 240 ? 145.582 152.713 142.194 1.00 50.36  ? 240 PHE B C   1 
ATOM   3276 O O   . PHE B 1 240 ? 145.191 152.709 143.365 1.00 51.66  ? 240 PHE B O   1 
ATOM   3277 C CB  . PHE B 1 240 ? 145.428 154.860 140.890 1.00 45.39  ? 240 PHE B CB  1 
ATOM   3278 C CG  . PHE B 1 240 ? 146.086 156.156 140.519 1.00 48.21  ? 240 PHE B CG  1 
ATOM   3279 C CD1 . PHE B 1 240 ? 147.017 156.733 141.358 1.00 47.48  ? 240 PHE B CD1 1 
ATOM   3280 C CD2 . PHE B 1 240 ? 145.783 156.792 139.334 1.00 51.11  ? 240 PHE B CD2 1 
ATOM   3281 C CE1 . PHE B 1 240 ? 147.627 157.919 141.027 1.00 46.62  ? 240 PHE B CE1 1 
ATOM   3282 C CE2 . PHE B 1 240 ? 146.396 157.978 139.000 1.00 51.06  ? 240 PHE B CE2 1 
ATOM   3283 C CZ  . PHE B 1 240 ? 147.317 158.540 139.849 1.00 47.02  ? 240 PHE B CZ  1 
ATOM   3284 N N   . CYS B 1 241 ? 145.383 151.675 141.376 1.00 54.74  ? 241 CYS B N   1 
ATOM   3285 C CA  . CYS B 1 241 ? 144.742 150.461 141.874 1.00 56.26  ? 241 CYS B CA  1 
ATOM   3286 C C   . CYS B 1 241 ? 145.547 149.832 143.004 1.00 53.28  ? 241 CYS B C   1 
ATOM   3287 O O   . CYS B 1 241 ? 144.983 149.438 144.030 1.00 50.70  ? 241 CYS B O   1 
ATOM   3288 C CB  . CYS B 1 241 ? 144.555 149.457 140.738 1.00 59.07  ? 241 CYS B CB  1 
ATOM   3289 S SG  . CYS B 1 241 ? 143.361 149.949 139.483 1.00 78.10  ? 241 CYS B SG  1 
ATOM   3290 N N   . GLY B 1 242 ? 146.867 149.733 142.837 1.00 51.20  ? 242 GLY B N   1 
ATOM   3291 C CA  . GLY B 1 242 ? 147.689 149.134 143.875 1.00 50.13  ? 242 GLY B CA  1 
ATOM   3292 C C   . GLY B 1 242 ? 147.710 149.948 145.154 1.00 50.58  ? 242 GLY B C   1 
ATOM   3293 O O   . GLY B 1 242 ? 147.615 149.394 146.255 1.00 47.76  ? 242 GLY B O   1 
ATOM   3294 N N   . ILE B 1 243 ? 147.838 151.272 145.029 1.00 49.50  ? 243 ILE B N   1 
ATOM   3295 C CA  . ILE B 1 243 ? 147.814 152.124 146.213 1.00 44.99  ? 243 ILE B CA  1 
ATOM   3296 C C   . ILE B 1 243 ? 146.472 152.004 146.919 1.00 46.30  ? 243 ILE B C   1 
ATOM   3297 O O   . ILE B 1 243 ? 146.405 151.950 148.153 1.00 47.95  ? 243 ILE B O   1 
ATOM   3298 C CB  . ILE B 1 243 ? 148.128 153.582 145.840 1.00 38.66  ? 243 ILE B CB  1 
ATOM   3299 C CG1 . ILE B 1 243 ? 149.516 153.694 145.220 1.00 41.21  ? 243 ILE B CG1 1 
ATOM   3300 C CG2 . ILE B 1 243 ? 148.053 154.460 147.061 1.00 44.48  ? 243 ILE B CG2 1 
ATOM   3301 C CD1 . ILE B 1 243 ? 149.861 155.087 144.759 1.00 40.84  ? 243 ILE B CD1 1 
ATOM   3302 N N   . PHE B 1 244 ? 145.382 151.948 146.149 1.00 45.21  ? 244 PHE B N   1 
ATOM   3303 C CA  . PHE B 1 244 ? 144.064 151.803 146.750 1.00 44.73  ? 244 PHE B CA  1 
ATOM   3304 C C   . PHE B 1 244 ? 143.931 150.471 147.472 1.00 47.00  ? 244 PHE B C   1 
ATOM   3305 O O   . PHE B 1 244 ? 143.362 150.411 148.563 1.00 51.15  ? 244 PHE B O   1 
ATOM   3306 C CB  . PHE B 1 244 ? 142.982 151.946 145.685 1.00 50.04  ? 244 PHE B CB  1 
ATOM   3307 C CG  . PHE B 1 244 ? 141.588 151.954 146.237 1.00 46.70  ? 244 PHE B CG  1 
ATOM   3308 C CD1 . PHE B 1 244 ? 141.072 153.088 146.825 1.00 43.99  ? 244 PHE B CD1 1 
ATOM   3309 C CD2 . PHE B 1 244 ? 140.793 150.830 146.163 1.00 47.88  ? 244 PHE B CD2 1 
ATOM   3310 C CE1 . PHE B 1 244 ? 139.793 153.097 147.331 1.00 47.77  ? 244 PHE B CE1 1 
ATOM   3311 C CE2 . PHE B 1 244 ? 139.512 150.840 146.665 1.00 49.38  ? 244 PHE B CE2 1 
ATOM   3312 C CZ  . PHE B 1 244 ? 139.014 151.975 147.249 1.00 47.85  ? 244 PHE B CZ  1 
ATOM   3313 N N   . ILE B 1 245 ? 144.455 149.394 146.884 1.00 46.18  ? 245 ILE B N   1 
ATOM   3314 C CA  . ILE B 1 245 ? 144.380 148.082 147.527 1.00 47.72  ? 245 ILE B CA  1 
ATOM   3315 C C   . ILE B 1 245 ? 145.133 148.092 148.850 1.00 52.81  ? 245 ILE B C   1 
ATOM   3316 O O   . ILE B 1 245 ? 144.622 147.638 149.886 1.00 57.96  ? 245 ILE B O   1 
ATOM   3317 C CB  . ILE B 1 245 ? 144.924 146.992 146.589 1.00 44.48  ? 245 ILE B CB  1 
ATOM   3318 C CG1 . ILE B 1 245 ? 143.954 146.739 145.438 1.00 51.57  ? 245 ILE B CG1 1 
ATOM   3319 C CG2 . ILE B 1 245 ? 145.192 145.714 147.358 1.00 39.42  ? 245 ILE B CG2 1 
ATOM   3320 C CD1 . ILE B 1 245 ? 144.446 145.711 144.444 1.00 51.30  ? 245 ILE B CD1 1 
ATOM   3321 N N   . VAL B 1 246 ? 146.366 148.605 148.836 1.00 49.07  ? 246 VAL B N   1 
ATOM   3322 C CA  . VAL B 1 246 ? 147.174 148.571 150.052 1.00 48.51  ? 246 VAL B CA  1 
ATOM   3323 C C   . VAL B 1 246 ? 146.562 149.460 151.127 1.00 50.23  ? 246 VAL B C   1 
ATOM   3324 O O   . VAL B 1 246 ? 146.486 149.074 152.299 1.00 52.72  ? 246 VAL B O   1 
ATOM   3325 C CB  . VAL B 1 246 ? 148.631 148.960 149.752 1.00 42.81  ? 246 VAL B CB  1 
ATOM   3326 C CG1 . VAL B 1 246 ? 149.476 148.763 150.985 1.00 40.64  ? 246 VAL B CG1 1 
ATOM   3327 C CG2 . VAL B 1 246 ? 149.171 148.117 148.627 1.00 44.89  ? 246 VAL B CG2 1 
ATOM   3328 N N   . LEU B 1 247 ? 146.099 150.654 150.751 1.00 48.53  ? 247 LEU B N   1 
ATOM   3329 C CA  . LEU B 1 247 ? 145.473 151.536 151.726 1.00 47.59  ? 247 LEU B CA  1 
ATOM   3330 C C   . LEU B 1 247 ? 144.156 150.968 152.233 1.00 56.15  ? 247 LEU B C   1 
ATOM   3331 O O   . LEU B 1 247 ? 143.792 151.201 153.387 1.00 64.07  ? 247 LEU B O   1 
ATOM   3332 C CB  . LEU B 1 247 ? 145.261 152.921 151.118 1.00 45.12  ? 247 LEU B CB  1 
ATOM   3333 C CG  . LEU B 1 247 ? 146.520 153.757 150.905 1.00 38.69  ? 247 LEU B CG  1 
ATOM   3334 C CD1 . LEU B 1 247 ? 146.203 155.030 150.158 1.00 40.74  ? 247 LEU B CD1 1 
ATOM   3335 C CD2 . LEU B 1 247 ? 147.140 154.079 152.239 1.00 46.79  ? 247 LEU B CD2 1 
ATOM   3336 N N   . ASN B 1 248 ? 143.432 150.220 151.400 1.00 54.59  ? 248 ASN B N   1 
ATOM   3337 C CA  . ASN B 1 248 ? 142.189 149.603 151.846 1.00 53.61  ? 248 ASN B CA  1 
ATOM   3338 C C   . ASN B 1 248 ? 142.457 148.520 152.880 1.00 59.39  ? 248 ASN B C   1 
ATOM   3339 O O   . ASN B 1 248 ? 141.759 148.439 153.900 1.00 62.81  ? 248 ASN B O   1 
ATOM   3340 C CB  . ASN B 1 248 ? 141.445 149.031 150.643 1.00 53.36  ? 248 ASN B CB  1 
ATOM   3341 C CG  . ASN B 1 248 ? 139.953 148.989 150.847 1.00 66.42  ? 248 ASN B CG  1 
ATOM   3342 O OD1 . ASN B 1 248 ? 139.362 147.917 150.975 1.00 71.40  ? 248 ASN B OD1 1 
ATOM   3343 N ND2 . ASN B 1 248 ? 139.329 150.158 150.871 1.00 65.47  ? 248 ASN B ND2 1 
ATOM   3344 N N   . ILE B 1 249 ? 143.474 147.688 152.644 1.00 57.81  ? 249 ILE B N   1 
ATOM   3345 C CA  . ILE B 1 249 ? 143.852 146.693 153.646 1.00 59.70  ? 249 ILE B CA  1 
ATOM   3346 C C   . ILE B 1 249 ? 144.344 147.379 154.917 1.00 63.68  ? 249 ILE B C   1 
ATOM   3347 O O   . ILE B 1 249 ? 144.078 146.917 156.034 1.00 62.27  ? 249 ILE B O   1 
ATOM   3348 C CB  . ILE B 1 249 ? 144.901 145.722 153.078 1.00 53.60  ? 249 ILE B CB  1 
ATOM   3349 C CG1 . ILE B 1 249 ? 144.322 144.963 151.887 1.00 55.78  ? 249 ILE B CG1 1 
ATOM   3350 C CG2 . ILE B 1 249 ? 145.357 144.746 154.146 1.00 53.79  ? 249 ILE B CG2 1 
ATOM   3351 C CD1 . ILE B 1 249 ? 145.236 143.892 151.345 1.00 59.36  ? 249 ILE B CD1 1 
ATOM   3352 N N   . THR B 1 250 ? 145.063 148.495 154.769 1.00 63.56  ? 250 THR B N   1 
ATOM   3353 C CA  . THR B 1 250 ? 145.499 149.258 155.935 1.00 62.58  ? 250 THR B CA  1 
ATOM   3354 C C   . THR B 1 250 ? 144.308 149.776 156.730 1.00 64.51  ? 250 THR B C   1 
ATOM   3355 O O   . THR B 1 250 ? 144.309 149.734 157.964 1.00 69.75  ? 250 THR B O   1 
ATOM   3356 C CB  . THR B 1 250 ? 146.395 150.416 155.494 1.00 58.10  ? 250 THR B CB  1 
ATOM   3357 O OG1 . THR B 1 250 ? 147.585 149.898 154.891 1.00 58.64  ? 250 THR B OG1 1 
ATOM   3358 C CG2 . THR B 1 250 ? 146.779 151.276 156.675 1.00 64.96  ? 250 THR B CG2 1 
ATOM   3359 N N   . LEU B 1 251 ? 143.283 150.272 156.037 1.00 62.23  ? 251 LEU B N   1 
ATOM   3360 C CA  . LEU B 1 251 ? 142.079 150.737 156.715 1.00 65.18  ? 251 LEU B CA  1 
ATOM   3361 C C   . LEU B 1 251 ? 141.387 149.598 157.448 1.00 70.75  ? 251 LEU B C   1 
ATOM   3362 O O   . LEU B 1 251 ? 140.901 149.779 158.569 1.00 78.86  ? 251 LEU B O   1 
ATOM   3363 C CB  . LEU B 1 251 ? 141.125 151.378 155.710 1.00 65.87  ? 251 LEU B CB  1 
ATOM   3364 C CG  . LEU B 1 251 ? 141.455 152.804 155.279 1.00 66.84  ? 251 LEU B CG  1 
ATOM   3365 C CD1 . LEU B 1 251 ? 140.614 153.210 154.084 1.00 59.99  ? 251 LEU B CD1 1 
ATOM   3366 C CD2 . LEU B 1 251 ? 141.228 153.745 156.439 1.00 68.46  ? 251 LEU B CD2 1 
ATOM   3367 N N   . VAL B 1 252 ? 141.319 148.421 156.824 1.00 67.39  ? 252 VAL B N   1 
ATOM   3368 C CA  . VAL B 1 252 ? 140.703 147.270 157.483 1.00 65.66  ? 252 VAL B CA  1 
ATOM   3369 C C   . VAL B 1 252 ? 141.466 146.916 158.755 1.00 72.64  ? 252 VAL B C   1 
ATOM   3370 O O   . VAL B 1 252 ? 140.874 146.702 159.823 1.00 74.80  ? 252 VAL B O   1 
ATOM   3371 C CB  . VAL B 1 252 ? 140.633 146.075 156.517 1.00 57.50  ? 252 VAL B CB  1 
ATOM   3372 C CG1 . VAL B 1 252 ? 140.171 144.833 157.247 1.00 58.49  ? 252 VAL B CG1 1 
ATOM   3373 C CG2 . VAL B 1 252 ? 139.707 146.387 155.360 1.00 54.80  ? 252 VAL B CG2 1 
ATOM   3374 N N   . LEU B 1 253 ? 142.798 146.872 158.662 1.00 71.55  ? 253 LEU B N   1 
ATOM   3375 C CA  . LEU B 1 253 ? 143.613 146.550 159.830 1.00 76.31  ? 253 LEU B CA  1 
ATOM   3376 C C   . LEU B 1 253 ? 143.435 147.587 160.929 1.00 83.35  ? 253 LEU B C   1 
ATOM   3377 O O   . LEU B 1 253 ? 143.308 147.238 162.109 1.00 88.76  ? 253 LEU B O   1 
ATOM   3378 C CB  . LEU B 1 253 ? 145.084 146.447 159.434 1.00 72.35  ? 253 LEU B CB  1 
ATOM   3379 C CG  . LEU B 1 253 ? 145.485 145.348 158.451 1.00 71.29  ? 253 LEU B CG  1 
ATOM   3380 C CD1 . LEU B 1 253 ? 146.951 145.480 158.093 1.00 74.78  ? 253 LEU B CD1 1 
ATOM   3381 C CD2 . LEU B 1 253 ? 145.196 143.979 159.031 1.00 71.21  ? 253 LEU B CD2 1 
ATOM   3382 N N   . ALA B 1 254 ? 143.427 148.869 160.563 1.00 79.10  ? 254 ALA B N   1 
ATOM   3383 C CA  . ALA B 1 254 ? 143.257 149.920 161.558 1.00 82.16  ? 254 ALA B CA  1 
ATOM   3384 C C   . ALA B 1 254 ? 141.900 149.811 162.237 1.00 86.07  ? 254 ALA B C   1 
ATOM   3385 O O   . ALA B 1 254 ? 141.803 149.870 163.465 1.00 94.44  ? 254 ALA B O   1 
ATOM   3386 C CB  . ALA B 1 254 ? 143.431 151.291 160.908 1.00 78.97  ? 254 ALA B CB  1 
ATOM   3387 N N   . ALA B 1 255 ? 140.840 149.623 161.450 1.00 83.10  ? 255 ALA B N   1 
ATOM   3388 C CA  . ALA B 1 255 ? 139.513 149.467 162.031 1.00 86.01  ? 255 ALA B CA  1 
ATOM   3389 C C   . ALA B 1 255 ? 139.454 148.275 162.971 1.00 93.06  ? 255 ALA B C   1 
ATOM   3390 O O   . ALA B 1 255 ? 138.730 148.312 163.972 1.00 101.23 ? 255 ALA B O   1 
ATOM   3391 C CB  . ALA B 1 255 ? 138.470 149.320 160.928 1.00 85.89  ? 255 ALA B CB  1 
ATOM   3392 N N   . VAL B 1 256 ? 140.201 147.212 162.672 1.00 92.36  ? 256 VAL B N   1 
ATOM   3393 C CA  . VAL B 1 256 ? 140.231 146.074 163.585 1.00 98.52  ? 256 VAL B CA  1 
ATOM   3394 C C   . VAL B 1 256 ? 140.977 146.424 164.870 1.00 101.06 ? 256 VAL B C   1 
ATOM   3395 O O   . VAL B 1 256 ? 140.538 146.071 165.971 1.00 99.65  ? 256 VAL B O   1 
ATOM   3396 C CB  . VAL B 1 256 ? 140.839 144.841 162.894 1.00 98.12  ? 256 VAL B CB  1 
ATOM   3397 C CG1 . VAL B 1 256 ? 141.052 143.723 163.899 1.00 98.41  ? 256 VAL B CG1 1 
ATOM   3398 C CG2 . VAL B 1 256 ? 139.930 144.369 161.777 1.00 94.67  ? 256 VAL B CG2 1 
ATOM   3399 N N   . PHE B 1 257 ? 142.105 147.129 164.762 1.00 101.28 ? 257 PHE B N   1 
ATOM   3400 C CA  . PHE B 1 257 ? 143.010 147.310 165.893 1.00 104.59 ? 257 PHE B CA  1 
ATOM   3401 C C   . PHE B 1 257 ? 143.067 148.743 166.417 1.00 108.70 ? 257 PHE B C   1 
ATOM   3402 O O   . PHE B 1 257 ? 144.035 149.103 167.093 1.00 109.94 ? 257 PHE B O   1 
ATOM   3403 C CB  . PHE B 1 257 ? 144.413 146.833 165.515 1.00 100.62 ? 257 PHE B CB  1 
ATOM   3404 C CG  . PHE B 1 257 ? 144.478 145.375 165.167 1.00 101.61 ? 257 PHE B CG  1 
ATOM   3405 C CD1 . PHE B 1 257 ? 144.471 144.413 166.160 1.00 104.30 ? 257 PHE B CD1 1 
ATOM   3406 C CD2 . PHE B 1 257 ? 144.537 144.968 163.847 1.00 101.36 ? 257 PHE B CD2 1 
ATOM   3407 C CE1 . PHE B 1 257 ? 144.527 143.069 165.845 1.00 107.91 ? 257 PHE B CE1 1 
ATOM   3408 C CE2 . PHE B 1 257 ? 144.593 143.626 163.523 1.00 105.21 ? 257 PHE B CE2 1 
ATOM   3409 C CZ  . PHE B 1 257 ? 144.588 142.675 164.524 1.00 110.13 ? 257 PHE B CZ  1 
ATOM   3410 N N   . LYS B 1 258 ? 142.058 149.562 166.137 1.00 110.17 ? 258 LYS B N   1 
ATOM   3411 C CA  . LYS B 1 258 ? 142.006 150.942 166.612 1.00 113.44 ? 258 LYS B CA  1 
ATOM   3412 C C   . LYS B 1 258 ? 140.566 151.209 167.045 1.00 118.93 ? 258 LYS B C   1 
ATOM   3413 O O   . LYS B 1 258 ? 139.796 150.283 167.332 1.00 115.49 ? 258 LYS B O   1 
ATOM   3414 C CB  . LYS B 1 258 ? 142.491 151.938 165.550 1.00 107.10 ? 258 LYS B CB  1 
ATOM   3415 C CG  . LYS B 1 258 ? 143.937 151.753 165.105 1.00 101.18 ? 258 LYS B CG  1 
ATOM   3416 C CD  . LYS B 1 258 ? 144.901 152.092 166.224 1.00 103.42 ? 258 LYS B CD  1 
ATOM   3417 C CE  . LYS B 1 258 ? 146.341 151.836 165.815 1.00 108.94 ? 258 LYS B CE  1 
ATOM   3418 N NZ  . LYS B 1 258 ? 147.295 152.146 166.916 1.00 114.29 ? 258 LYS B NZ  1 
ATOM   3419 N N   . LEU B 1 259 ? 140.201 152.492 167.125 1.00 124.67 ? 259 LEU B N   1 
ATOM   3420 C CA  . LEU B 1 259 ? 138.828 152.902 167.412 1.00 132.36 ? 259 LEU B CA  1 
ATOM   3421 C C   . LEU B 1 259 ? 138.348 152.425 168.777 1.00 138.83 ? 259 LEU B C   1 
ATOM   3422 O O   . LEU B 1 259 ? 137.472 151.557 168.863 1.00 138.32 ? 259 LEU B O   1 
ATOM   3423 C CB  . LEU B 1 259 ? 137.872 152.387 166.331 1.00 128.47 ? 259 LEU B CB  1 
ATOM   3424 C CG  . LEU B 1 259 ? 138.252 152.588 164.867 1.00 120.24 ? 259 LEU B CG  1 
ATOM   3425 C CD1 . LEU B 1 259 ? 137.220 151.919 163.973 1.00 115.48 ? 259 LEU B CD1 1 
ATOM   3426 C CD2 . LEU B 1 259 ? 138.376 154.063 164.544 1.00 118.73 ? 259 LEU B CD2 1 
ATOM   3427 N N   . GLU B 1 260 ? 138.932 152.970 169.844 1.00 143.20 ? 260 GLU B N   1 
ATOM   3428 C CA  . GLU B 1 260 ? 138.554 152.622 171.210 1.00 145.01 ? 260 GLU B CA  1 
ATOM   3429 C C   . GLU B 1 260 ? 137.056 152.795 171.448 1.00 147.43 ? 260 GLU B C   1 
ATOM   3430 O O   . GLU B 1 260 ? 136.369 153.471 170.675 1.00 147.52 ? 260 GLU B O   1 
ATOM   3431 C CB  . GLU B 1 260 ? 139.352 153.459 172.211 1.00 147.72 ? 260 GLU B CB  1 
ATOM   3432 C CG  . GLU B 1 260 ? 140.382 154.386 171.584 1.00 145.34 ? 260 GLU B CG  1 
ATOM   3433 C CD  . GLU B 1 260 ? 139.783 155.702 171.135 1.00 147.83 ? 260 GLU B CD  1 
ATOM   3434 O OE1 . GLU B 1 260 ? 138.542 155.814 171.122 1.00 150.58 ? 260 GLU B OE1 1 
ATOM   3435 O OE2 . GLU B 1 260 ? 140.552 156.627 170.803 1.00 147.54 ? 260 GLU B OE2 1 
ATOM   3436 N N   . THR B 1 261 ? 136.559 152.199 172.536 1.00 148.19 ? 261 THR B N   1 
ATOM   3437 C CA  . THR B 1 261 ? 135.128 151.946 172.690 1.00 151.37 ? 261 THR B CA  1 
ATOM   3438 C C   . THR B 1 261 ? 134.293 153.218 172.578 1.00 153.12 ? 261 THR B C   1 
ATOM   3439 O O   . THR B 1 261 ? 133.180 153.188 172.041 1.00 149.42 ? 261 THR B O   1 
ATOM   3440 C CB  . THR B 1 261 ? 134.864 151.266 174.033 1.00 152.73 ? 261 THR B CB  1 
ATOM   3441 O OG1 . THR B 1 261 ? 135.249 152.146 175.097 1.00 154.15 ? 261 THR B OG1 1 
ATOM   3442 C CG2 . THR B 1 261 ? 135.661 149.974 174.141 1.00 151.76 ? 261 THR B CG2 1 
ATOM   3443 N N   . ASP B 1 262 ? 134.800 154.341 173.081 1.00 154.59 ? 262 ASP B N   1 
ATOM   3444 C CA  . ASP B 1 262 ? 133.980 155.544 173.169 1.00 154.67 ? 262 ASP B CA  1 
ATOM   3445 C C   . ASP B 1 262 ? 133.779 156.248 171.831 1.00 153.52 ? 262 ASP B C   1 
ATOM   3446 O O   . ASP B 1 262 ? 132.985 157.193 171.766 1.00 152.44 ? 262 ASP B O   1 
ATOM   3447 C CB  . ASP B 1 262 ? 134.580 156.521 174.186 1.00 157.17 ? 262 ASP B CB  1 
ATOM   3448 C CG  . ASP B 1 262 ? 136.005 156.916 173.854 1.00 159.97 ? 262 ASP B CG  1 
ATOM   3449 O OD1 . ASP B 1 262 ? 136.529 156.463 172.817 1.00 156.37 ? 262 ASP B OD1 1 
ATOM   3450 O OD2 . ASP B 1 262 ? 136.605 157.683 174.637 1.00 164.79 ? 262 ASP B OD2 1 
ATOM   3451 N N   . ARG B 1 263 ? 134.468 155.829 170.771 1.00 153.05 ? 263 ARG B N   1 
ATOM   3452 C CA  . ARG B 1 263 ? 134.274 156.454 169.469 1.00 149.68 ? 263 ARG B CA  1 
ATOM   3453 C C   . ARG B 1 263 ? 132.904 156.105 168.900 1.00 145.08 ? 263 ARG B C   1 
ATOM   3454 O O   . ARG B 1 263 ? 132.418 154.980 169.043 1.00 143.19 ? 263 ARG B O   1 
ATOM   3455 C CB  . ARG B 1 263 ? 135.372 156.027 168.496 1.00 146.99 ? 263 ARG B CB  1 
ATOM   3456 C CG  . ARG B 1 263 ? 136.699 156.737 168.712 1.00 146.88 ? 263 ARG B CG  1 
ATOM   3457 C CD  . ARG B 1 263 ? 137.633 156.562 167.522 1.00 141.06 ? 263 ARG B CD  1 
ATOM   3458 N NE  . ARG B 1 263 ? 138.968 157.079 167.801 1.00 143.31 ? 263 ARG B NE  1 
ATOM   3459 C CZ  . ARG B 1 263 ? 139.936 157.191 166.901 1.00 135.18 ? 263 ARG B CZ  1 
ATOM   3460 N NH1 . ARG B 1 263 ? 139.746 156.856 165.635 1.00 126.75 ? 263 ARG B NH1 1 
ATOM   3461 N NH2 . ARG B 1 263 ? 141.124 157.654 167.279 1.00 131.77 ? 263 ARG B NH2 1 
ATOM   3462 N N   . SER B 1 264 ? 132.279 157.088 168.247 1.00 145.74 ? 264 SER B N   1 
ATOM   3463 C CA  . SER B 1 264 ? 130.935 156.893 167.712 1.00 141.51 ? 264 SER B CA  1 
ATOM   3464 C C   . SER B 1 264 ? 130.945 155.998 166.477 1.00 130.43 ? 264 SER B C   1 
ATOM   3465 O O   . SER B 1 264 ? 130.027 155.192 166.285 1.00 128.04 ? 264 SER B O   1 
ATOM   3466 C CB  . SER B 1 264 ? 130.302 158.247 167.394 1.00 142.52 ? 264 SER B CB  1 
ATOM   3467 O OG  . SER B 1 264 ? 131.183 159.059 166.638 1.00 147.06 ? 264 SER B OG  1 
ATOM   3468 N N   . ILE B 1 265 ? 131.958 156.149 165.620 1.00 125.05 ? 265 ILE B N   1 
ATOM   3469 C CA  . ILE B 1 265 ? 132.191 155.302 164.450 1.00 117.64 ? 265 ILE B CA  1 
ATOM   3470 C C   . ILE B 1 265 ? 131.113 155.491 163.389 1.00 108.16 ? 265 ILE B C   1 
ATOM   3471 O O   . ILE B 1 265 ? 131.416 155.858 162.249 1.00 104.72 ? 265 ILE B O   1 
ATOM   3472 C CB  . ILE B 1 265 ? 132.303 153.819 164.849 1.00 116.79 ? 265 ILE B CB  1 
ATOM   3473 C CG1 . ILE B 1 265 ? 133.489 153.620 165.791 1.00 121.95 ? 265 ILE B CG1 1 
ATOM   3474 C CG2 . ILE B 1 265 ? 132.432 152.941 163.616 1.00 108.74 ? 265 ILE B CG2 1 
ATOM   3475 C CD1 . ILE B 1 265 ? 134.767 154.250 165.291 1.00 124.75 ? 265 ILE B CD1 1 
ATOM   3476 N N   . TRP B 1 266 ? 129.858 155.227 163.745 1.00 108.41 ? 266 TRP B N   1 
ATOM   3477 C CA  . TRP B 1 266 ? 128.785 155.280 162.755 1.00 102.75 ? 266 TRP B CA  1 
ATOM   3478 C C   . TRP B 1 266 ? 128.639 156.630 162.062 1.00 99.33  ? 266 TRP B C   1 
ATOM   3479 O O   . TRP B 1 266 ? 128.339 156.634 160.856 1.00 95.96  ? 266 TRP B O   1 
ATOM   3480 C CB  . TRP B 1 266 ? 127.459 154.851 163.394 1.00 104.79 ? 266 TRP B CB  1 
ATOM   3481 C CG  . TRP B 1 266 ? 127.319 153.366 163.492 1.00 105.50 ? 266 TRP B CG  1 
ATOM   3482 C CD1 . TRP B 1 266 ? 127.225 152.625 164.632 1.00 107.34 ? 266 TRP B CD1 1 
ATOM   3483 C CD2 . TRP B 1 266 ? 127.276 152.437 162.405 1.00 103.58 ? 266 TRP B CD2 1 
ATOM   3484 N NE1 . TRP B 1 266 ? 127.116 151.292 164.322 1.00 105.95 ? 266 TRP B NE1 1 
ATOM   3485 C CE2 . TRP B 1 266 ? 127.146 151.151 162.960 1.00 103.76 ? 266 TRP B CE2 1 
ATOM   3486 C CE3 . TRP B 1 266 ? 127.330 152.568 161.015 1.00 102.06 ? 266 TRP B CE3 1 
ATOM   3487 C CZ2 . TRP B 1 266 ? 127.072 150.004 162.177 1.00 100.18 ? 266 TRP B CZ2 1 
ATOM   3488 C CZ3 . TRP B 1 266 ? 127.257 151.429 160.238 1.00 98.96  ? 266 TRP B CZ3 1 
ATOM   3489 C CH2 . TRP B 1 266 ? 127.129 150.164 160.820 1.00 99.71  ? 266 TRP B CH2 1 
ATOM   3490 N N   . PRO B 1 267 ? 128.775 157.783 162.728 1.00 104.41 ? 267 PRO B N   1 
ATOM   3491 C CA  . PRO B 1 267 ? 128.775 159.041 161.962 1.00 99.74  ? 267 PRO B CA  1 
ATOM   3492 C C   . PRO B 1 267 ? 129.851 159.093 160.893 1.00 92.93  ? 267 PRO B C   1 
ATOM   3493 O O   . PRO B 1 267 ? 129.600 159.597 159.793 1.00 89.94  ? 267 PRO B O   1 
ATOM   3494 C CB  . PRO B 1 267 ? 128.993 160.104 163.045 1.00 105.08 ? 267 PRO B CB  1 
ATOM   3495 C CG  . PRO B 1 267 ? 128.408 159.505 164.259 1.00 110.79 ? 267 PRO B CG  1 
ATOM   3496 C CD  . PRO B 1 267 ? 128.719 158.037 164.178 1.00 111.84 ? 267 PRO B CD  1 
ATOM   3497 N N   . LEU B 1 268 ? 131.044 158.569 161.181 1.00 94.10  ? 268 LEU B N   1 
ATOM   3498 C CA  . LEU B 1 268 ? 132.108 158.547 160.180 1.00 86.58  ? 268 LEU B CA  1 
ATOM   3499 C C   . LEU B 1 268 ? 131.738 157.658 159.001 1.00 83.84  ? 268 LEU B C   1 
ATOM   3500 O O   . LEU B 1 268 ? 132.005 158.003 157.842 1.00 78.43  ? 268 LEU B O   1 
ATOM   3501 C CB  . LEU B 1 268 ? 133.410 158.071 160.816 1.00 79.24  ? 268 LEU B CB  1 
ATOM   3502 C CG  . LEU B 1 268 ? 134.682 158.525 160.116 1.00 71.87  ? 268 LEU B CG  1 
ATOM   3503 C CD1 . LEU B 1 268 ? 134.751 160.036 160.165 1.00 74.98  ? 268 LEU B CD1 1 
ATOM   3504 C CD2 . LEU B 1 268 ? 135.895 157.904 160.774 1.00 72.11  ? 268 LEU B CD2 1 
ATOM   3505 N N   . ILE B 1 269 ? 131.134 156.503 159.282 1.00 86.74  ? 269 ILE B N   1 
ATOM   3506 C CA  . ILE B 1 269 ? 130.678 155.617 158.218 1.00 82.70  ? 269 ILE B CA  1 
ATOM   3507 C C   . ILE B 1 269 ? 129.618 156.307 157.375 1.00 78.32  ? 269 ILE B C   1 
ATOM   3508 O O   . ILE B 1 269 ? 129.622 156.209 156.144 1.00 74.66  ? 269 ILE B O   1 
ATOM   3509 C CB  . ILE B 1 269 ? 130.156 154.299 158.812 1.00 88.16  ? 269 ILE B CB  1 
ATOM   3510 C CG1 . ILE B 1 269 ? 131.229 153.658 159.693 1.00 92.98  ? 269 ILE B CG1 1 
ATOM   3511 C CG2 . ILE B 1 269 ? 129.710 153.359 157.710 1.00 85.12  ? 269 ILE B CG2 1 
ATOM   3512 C CD1 . ILE B 1 269 ? 132.552 153.450 158.996 1.00 89.60  ? 269 ILE B CD1 1 
ATOM   3513 N N   . ARG B 1 270 ? 128.694 157.015 158.024 1.00 83.19  ? 270 ARG B N   1 
ATOM   3514 C CA  . ARG B 1 270 ? 127.669 157.744 157.287 1.00 84.06  ? 270 ARG B CA  1 
ATOM   3515 C C   . ARG B 1 270 ? 128.287 158.821 156.408 1.00 80.61  ? 270 ARG B C   1 
ATOM   3516 O O   . ARG B 1 270 ? 127.834 159.047 155.281 1.00 81.79  ? 270 ARG B O   1 
ATOM   3517 C CB  . ARG B 1 270 ? 126.657 158.353 158.255 1.00 89.31  ? 270 ARG B CB  1 
ATOM   3518 C CG  . ARG B 1 270 ? 125.714 157.344 158.894 1.00 94.45  ? 270 ARG B CG  1 
ATOM   3519 C CD  . ARG B 1 270 ? 124.771 158.028 159.871 1.00 98.47  ? 270 ARG B CD  1 
ATOM   3520 N NE  . ARG B 1 270 ? 123.821 157.106 160.481 1.00 104.30 ? 270 ARG B NE  1 
ATOM   3521 C CZ  . ARG B 1 270 ? 123.006 157.427 161.478 1.00 109.53 ? 270 ARG B CZ  1 
ATOM   3522 N NH1 . ARG B 1 270 ? 123.010 158.636 162.011 1.00 109.92 ? 270 ARG B NH1 1 
ATOM   3523 N NH2 . ARG B 1 270 ? 122.169 156.510 161.952 1.00 108.87 ? 270 ARG B NH2 1 
ATOM   3524 N N   . ILE B 1 271 ? 129.319 159.502 156.904 1.00 76.51  ? 271 ILE B N   1 
ATOM   3525 C CA  . ILE B 1 271 ? 129.952 160.544 156.104 1.00 71.77  ? 271 ILE B CA  1 
ATOM   3526 C C   . ILE B 1 271 ? 130.661 159.947 154.896 1.00 72.21  ? 271 ILE B C   1 
ATOM   3527 O O   . ILE B 1 271 ? 130.491 160.420 153.768 1.00 74.77  ? 271 ILE B O   1 
ATOM   3528 C CB  . ILE B 1 271 ? 130.916 161.376 156.964 1.00 72.60  ? 271 ILE B CB  1 
ATOM   3529 C CG1 . ILE B 1 271 ? 130.151 162.105 158.063 1.00 82.04  ? 271 ILE B CG1 1 
ATOM   3530 C CG2 . ILE B 1 271 ? 131.650 162.376 156.103 1.00 73.88  ? 271 ILE B CG2 1 
ATOM   3531 C CD1 . ILE B 1 271 ? 128.986 162.902 157.551 1.00 87.90  ? 271 ILE B CD1 1 
ATOM   3532 N N   . TYR B 1 272 ? 131.455 158.898 155.102 1.00 70.40  ? 272 TYR B N   1 
ATOM   3533 C CA  . TYR B 1 272 ? 132.292 158.367 154.031 1.00 65.86  ? 272 TYR B CA  1 
ATOM   3534 C C   . TYR B 1 272 ? 131.577 157.369 153.126 1.00 66.80  ? 272 TYR B C   1 
ATOM   3535 O O   . TYR B 1 272 ? 132.146 156.969 152.099 1.00 66.42  ? 272 TYR B O   1 
ATOM   3536 C CB  . TYR B 1 272 ? 133.547 157.719 154.619 1.00 64.66  ? 272 TYR B CB  1 
ATOM   3537 C CG  . TYR B 1 272 ? 134.577 158.723 155.074 1.00 62.04  ? 272 TYR B CG  1 
ATOM   3538 C CD1 . TYR B 1 272 ? 135.310 159.453 154.152 1.00 61.62  ? 272 TYR B CD1 1 
ATOM   3539 C CD2 . TYR B 1 272 ? 134.817 158.944 156.421 1.00 64.07  ? 272 TYR B CD2 1 
ATOM   3540 C CE1 . TYR B 1 272 ? 136.248 160.371 154.555 1.00 62.23  ? 272 TYR B CE1 1 
ATOM   3541 C CE2 . TYR B 1 272 ? 135.758 159.859 156.832 1.00 65.39  ? 272 TYR B CE2 1 
ATOM   3542 C CZ  . TYR B 1 272 ? 136.470 160.569 155.894 1.00 64.28  ? 272 TYR B CZ  1 
ATOM   3543 O OH  . TYR B 1 272 ? 137.411 161.486 156.293 1.00 70.70  ? 272 TYR B OH  1 
ATOM   3544 N N   . ARG B 1 273 ? 130.351 156.966 153.466 1.00 66.71  ? 273 ARG B N   1 
ATOM   3545 C CA  . ARG B 1 273 ? 129.615 156.051 152.604 1.00 59.28  ? 273 ARG B CA  1 
ATOM   3546 C C   . ARG B 1 273 ? 129.342 156.674 151.245 1.00 62.73  ? 273 ARG B C   1 
ATOM   3547 O O   . ARG B 1 273 ? 129.420 155.992 150.221 1.00 62.10  ? 273 ARG B O   1 
ATOM   3548 C CB  . ARG B 1 273 ? 128.310 155.631 153.275 1.00 64.07  ? 273 ARG B CB  1 
ATOM   3549 C CG  . ARG B 1 273 ? 127.303 154.994 152.331 1.00 69.56  ? 273 ARG B CG  1 
ATOM   3550 C CD  . ARG B 1 273 ? 126.057 154.547 153.070 1.00 73.26  ? 273 ARG B CD  1 
ATOM   3551 N NE  . ARG B 1 273 ? 125.461 155.633 153.837 1.00 72.40  ? 273 ARG B NE  1 
ATOM   3552 C CZ  . ARG B 1 273 ? 124.488 155.478 154.724 1.00 77.28  ? 273 ARG B CZ  1 
ATOM   3553 N NH1 . ARG B 1 273 ? 123.977 154.288 154.987 1.00 81.35  ? 273 ARG B NH1 1 
ATOM   3554 N NH2 . ARG B 1 273 ? 124.019 156.543 155.365 1.00 80.74  ? 273 ARG B NH2 1 
ATOM   3555 N N   . GLY B 1 274 ? 129.008 157.963 151.213 1.00 63.72  ? 274 GLY B N   1 
ATOM   3556 C CA  . GLY B 1 274 ? 128.763 158.609 149.934 1.00 64.07  ? 274 GLY B CA  1 
ATOM   3557 C C   . GLY B 1 274 ? 129.989 158.594 149.045 1.00 62.70  ? 274 GLY B C   1 
ATOM   3558 O O   . GLY B 1 274 ? 129.905 158.306 147.847 1.00 60.52  ? 274 GLY B O   1 
ATOM   3559 N N   . GLY B 1 275 ? 131.151 158.890 149.626 1.00 60.09  ? 275 GLY B N   1 
ATOM   3560 C CA  . GLY B 1 275 ? 132.377 158.846 148.853 1.00 58.97  ? 275 GLY B CA  1 
ATOM   3561 C C   . GLY B 1 275 ? 132.682 157.456 148.338 1.00 56.52  ? 275 GLY B C   1 
ATOM   3562 O O   . GLY B 1 275 ? 133.055 157.284 147.174 1.00 59.89  ? 275 GLY B O   1 
ATOM   3563 N N   . PHE B 1 276 ? 132.514 156.441 149.191 1.00 56.76  ? 276 PHE B N   1 
ATOM   3564 C CA  . PHE B 1 276 ? 132.770 155.079 148.735 1.00 53.41  ? 276 PHE B CA  1 
ATOM   3565 C C   . PHE B 1 276 ? 131.806 154.680 147.629 1.00 51.92  ? 276 PHE B C   1 
ATOM   3566 O O   . PHE B 1 276 ? 132.196 154.001 146.674 1.00 54.66  ? 276 PHE B O   1 
ATOM   3567 C CB  . PHE B 1 276 ? 132.680 154.082 149.886 1.00 50.51  ? 276 PHE B CB  1 
ATOM   3568 C CG  . PHE B 1 276 ? 132.807 152.653 149.443 1.00 48.45  ? 276 PHE B CG  1 
ATOM   3569 C CD1 . PHE B 1 276 ? 134.046 152.113 149.159 1.00 55.33  ? 276 PHE B CD1 1 
ATOM   3570 C CD2 . PHE B 1 276 ? 131.685 151.857 149.285 1.00 51.00  ? 276 PHE B CD2 1 
ATOM   3571 C CE1 . PHE B 1 276 ? 134.165 150.804 148.738 1.00 59.03  ? 276 PHE B CE1 1 
ATOM   3572 C CE2 . PHE B 1 276 ? 131.798 150.547 148.865 1.00 49.71  ? 276 PHE B CE2 1 
ATOM   3573 C CZ  . PHE B 1 276 ? 133.038 150.019 148.594 1.00 53.54  ? 276 PHE B CZ  1 
ATOM   3574 N N   . LEU B 1 277 ? 130.539 155.076 147.752 1.00 52.78  ? 277 LEU B N   1 
ATOM   3575 C CA  . LEU B 1 277 ? 129.561 154.750 146.725 1.00 53.51  ? 277 LEU B CA  1 
ATOM   3576 C C   . LEU B 1 277 ? 129.925 155.400 145.402 1.00 52.39  ? 277 LEU B C   1 
ATOM   3577 O O   . LEU B 1 277 ? 129.804 154.777 144.344 1.00 45.75  ? 277 LEU B O   1 
ATOM   3578 C CB  . LEU B 1 277 ? 128.168 155.185 147.169 1.00 51.84  ? 277 LEU B CB  1 
ATOM   3579 C CG  . LEU B 1 277 ? 127.264 154.126 147.792 1.00 51.51  ? 277 LEU B CG  1 
ATOM   3580 C CD1 . LEU B 1 277 ? 127.923 153.474 148.987 1.00 55.35  ? 277 LEU B CD1 1 
ATOM   3581 C CD2 . LEU B 1 277 ? 125.948 154.756 148.189 1.00 50.79  ? 277 LEU B CD2 1 
ATOM   3582 N N   . LEU B 1 278 ? 130.382 156.652 145.441 1.00 55.71  ? 278 LEU B N   1 
ATOM   3583 C CA  . LEU B 1 278 ? 130.784 157.321 144.208 1.00 50.73  ? 278 LEU B CA  1 
ATOM   3584 C C   . LEU B 1 278 ? 132.001 156.648 143.577 1.00 50.13  ? 278 LEU B C   1 
ATOM   3585 O O   . LEU B 1 278 ? 132.060 156.474 142.353 1.00 52.84  ? 278 LEU B O   1 
ATOM   3586 C CB  . LEU B 1 278 ? 131.063 158.794 144.484 1.00 48.08  ? 278 LEU B CB  1 
ATOM   3587 C CG  . LEU B 1 278 ? 131.300 159.641 143.241 1.00 52.13  ? 278 LEU B CG  1 
ATOM   3588 C CD1 . LEU B 1 278 ? 130.134 159.496 142.286 1.00 55.44  ? 278 LEU B CD1 1 
ATOM   3589 C CD2 . LEU B 1 278 ? 131.494 161.088 143.638 1.00 68.45  ? 278 LEU B CD2 1 
ATOM   3590 N N   . ILE B 1 279 ? 132.982 156.260 144.395 1.00 50.65  ? 279 ILE B N   1 
ATOM   3591 C CA  . ILE B 1 279 ? 134.170 155.592 143.862 1.00 45.72  ? 279 ILE B CA  1 
ATOM   3592 C C   . ILE B 1 279 ? 133.793 154.259 143.230 1.00 46.61  ? 279 ILE B C   1 
ATOM   3593 O O   . ILE B 1 279 ? 134.236 153.925 142.123 1.00 53.64  ? 279 ILE B O   1 
ATOM   3594 C CB  . ILE B 1 279 ? 135.219 155.400 144.968 1.00 47.64  ? 279 ILE B CB  1 
ATOM   3595 C CG1 . ILE B 1 279 ? 135.639 156.742 145.546 1.00 52.18  ? 279 ILE B CG1 1 
ATOM   3596 C CG2 . ILE B 1 279 ? 136.428 154.679 144.428 1.00 47.55  ? 279 ILE B CG2 1 
ATOM   3597 C CD1 . ILE B 1 279 ? 136.293 156.608 146.878 1.00 50.79  ? 279 ILE B CD1 1 
ATOM   3598 N N   . GLU B 1 280 ? 132.972 153.473 143.929 1.00 43.24  ? 280 GLU B N   1 
ATOM   3599 C CA  . GLU B 1 280 ? 132.537 152.194 143.387 1.00 43.40  ? 280 GLU B CA  1 
ATOM   3600 C C   . GLU B 1 280 ? 131.732 152.393 142.115 1.00 48.64  ? 280 GLU B C   1 
ATOM   3601 O O   . GLU B 1 280 ? 131.855 151.613 141.167 1.00 49.13  ? 280 GLU B O   1 
ATOM   3602 C CB  . GLU B 1 280 ? 131.714 151.432 144.421 1.00 46.98  ? 280 GLU B CB  1 
ATOM   3603 C CG  . GLU B 1 280 ? 131.138 150.130 143.895 1.00 51.72  ? 280 GLU B CG  1 
ATOM   3604 C CD  . GLU B 1 280 ? 129.993 149.608 144.735 1.00 59.67  ? 280 GLU B CD  1 
ATOM   3605 O OE1 . GLU B 1 280 ? 129.621 150.278 145.719 1.00 63.74  ? 280 GLU B OE1 1 
ATOM   3606 O OE2 . GLU B 1 280 ? 129.462 148.527 144.411 1.00 58.09  ? 280 GLU B OE2 1 
ATOM   3607 N N   . PHE B 1 281 ? 130.896 153.431 142.078 1.00 50.88  ? 281 PHE B N   1 
ATOM   3608 C CA  . PHE B 1 281 ? 130.112 153.705 140.883 1.00 47.42  ? 281 PHE B CA  1 
ATOM   3609 C C   . PHE B 1 281 ? 131.010 154.018 139.696 1.00 44.83  ? 281 PHE B C   1 
ATOM   3610 O O   . PHE B 1 281 ? 130.778 153.520 138.592 1.00 43.27  ? 281 PHE B O   1 
ATOM   3611 C CB  . PHE B 1 281 ? 129.146 154.854 141.153 1.00 43.67  ? 281 PHE B CB  1 
ATOM   3612 C CG  . PHE B 1 281 ? 128.401 155.305 139.943 1.00 41.97  ? 281 PHE B CG  1 
ATOM   3613 C CD1 . PHE B 1 281 ? 127.381 154.538 139.420 1.00 44.02  ? 281 PHE B CD1 1 
ATOM   3614 C CD2 . PHE B 1 281 ? 128.719 156.497 139.326 1.00 43.76  ? 281 PHE B CD2 1 
ATOM   3615 C CE1 . PHE B 1 281 ? 126.699 154.949 138.305 1.00 46.77  ? 281 PHE B CE1 1 
ATOM   3616 C CE2 . PHE B 1 281 ? 128.037 156.912 138.211 1.00 44.85  ? 281 PHE B CE2 1 
ATOM   3617 C CZ  . PHE B 1 281 ? 127.026 156.137 137.699 1.00 46.85  ? 281 PHE B CZ  1 
ATOM   3618 N N   . LEU B 1 282 ? 132.054 154.824 139.906 1.00 44.68  ? 282 LEU B N   1 
ATOM   3619 C CA  . LEU B 1 282 ? 132.977 155.128 138.813 1.00 40.07  ? 282 LEU B CA  1 
ATOM   3620 C C   . LEU B 1 282 ? 133.720 153.883 138.343 1.00 44.48  ? 282 LEU B C   1 
ATOM   3621 O O   . LEU B 1 282 ? 133.892 153.669 137.136 1.00 49.23  ? 282 LEU B O   1 
ATOM   3622 C CB  . LEU B 1 282 ? 133.964 156.208 139.243 1.00 38.02  ? 282 LEU B CB  1 
ATOM   3623 C CG  . LEU B 1 282 ? 133.371 157.602 139.436 1.00 42.52  ? 282 LEU B CG  1 
ATOM   3624 C CD1 . LEU B 1 282 ? 134.465 158.600 139.741 1.00 44.33  ? 282 LEU B CD1 1 
ATOM   3625 C CD2 . LEU B 1 282 ? 132.599 158.020 138.204 1.00 45.56  ? 282 LEU B CD2 1 
ATOM   3626 N N   . PHE B 1 283 ? 134.171 153.048 139.281 1.00 45.42  ? 283 PHE B N   1 
ATOM   3627 C CA  . PHE B 1 283 ? 134.878 151.824 138.909 1.00 42.73  ? 283 PHE B CA  1 
ATOM   3628 C C   . PHE B 1 283 ? 133.976 150.885 138.108 1.00 46.17  ? 283 PHE B C   1 
ATOM   3629 O O   . PHE B 1 283 ? 134.353 150.396 137.030 1.00 48.63  ? 283 PHE B O   1 
ATOM   3630 C CB  . PHE B 1 283 ? 135.409 151.152 140.178 1.00 42.96  ? 283 PHE B CB  1 
ATOM   3631 C CG  . PHE B 1 283 ? 135.908 149.751 139.981 1.00 51.01  ? 283 PHE B CG  1 
ATOM   3632 C CD1 . PHE B 1 283 ? 136.915 149.478 139.079 1.00 55.55  ? 283 PHE B CD1 1 
ATOM   3633 C CD2 . PHE B 1 283 ? 135.394 148.710 140.734 1.00 51.33  ? 283 PHE B CD2 1 
ATOM   3634 C CE1 . PHE B 1 283 ? 137.377 148.186 138.914 1.00 53.04  ? 283 PHE B CE1 1 
ATOM   3635 C CE2 . PHE B 1 283 ? 135.856 147.421 140.574 1.00 46.69  ? 283 PHE B CE2 1 
ATOM   3636 C CZ  . PHE B 1 283 ? 136.846 147.159 139.665 1.00 45.45  ? 283 PHE B CZ  1 
ATOM   3637 N N   . LEU B 1 284 ? 132.760 150.651 138.602 1.00 43.55  ? 284 LEU B N   1 
ATOM   3638 C CA  . LEU B 1 284 ? 131.832 149.778 137.897 1.00 42.81  ? 284 LEU B CA  1 
ATOM   3639 C C   . LEU B 1 284 ? 131.391 150.382 136.570 1.00 46.78  ? 284 LEU B C   1 
ATOM   3640 O O   . LEU B 1 284 ? 131.091 149.645 135.626 1.00 47.14  ? 284 LEU B O   1 
ATOM   3641 C CB  . LEU B 1 284 ? 130.627 149.475 138.783 1.00 36.79  ? 284 LEU B CB  1 
ATOM   3642 C CG  . LEU B 1 284 ? 130.946 148.795 140.116 1.00 31.87  ? 284 LEU B CG  1 
ATOM   3643 C CD1 . LEU B 1 284 ? 129.686 148.536 140.905 1.00 36.68  ? 284 LEU B CD1 1 
ATOM   3644 C CD2 . LEU B 1 284 ? 131.700 147.512 139.896 1.00 38.15  ? 284 LEU B CD2 1 
ATOM   3645 N N   . LEU B 1 285 ? 131.366 151.711 136.462 1.00 45.12  ? 285 LEU B N   1 
ATOM   3646 C CA  . LEU B 1 285 ? 131.029 152.337 135.189 1.00 42.72  ? 285 LEU B CA  1 
ATOM   3647 C C   . LEU B 1 285 ? 132.155 152.180 134.176 1.00 44.28  ? 285 LEU B C   1 
ATOM   3648 O O   . LEU B 1 285 ? 131.895 152.039 132.975 1.00 46.79  ? 285 LEU B O   1 
ATOM   3649 C CB  . LEU B 1 285 ? 130.695 153.809 135.412 1.00 41.74  ? 285 LEU B CB  1 
ATOM   3650 C CG  . LEU B 1 285 ? 130.062 154.578 134.258 1.00 43.94  ? 285 LEU B CG  1 
ATOM   3651 C CD1 . LEU B 1 285 ? 128.930 153.792 133.640 1.00 46.53  ? 285 LEU B CD1 1 
ATOM   3652 C CD2 . LEU B 1 285 ? 129.552 155.894 134.775 1.00 42.12  ? 285 LEU B CD2 1 
ATOM   3653 N N   . GLY B 1 286 ? 133.405 152.199 134.635 1.00 43.96  ? 286 GLY B N   1 
ATOM   3654 C CA  . GLY B 1 286 ? 134.498 151.822 133.755 1.00 43.56  ? 286 GLY B CA  1 
ATOM   3655 C C   . GLY B 1 286 ? 134.355 150.396 133.260 1.00 46.34  ? 286 GLY B C   1 
ATOM   3656 O O   . GLY B 1 286 ? 134.558 150.112 132.073 1.00 53.08  ? 286 GLY B O   1 
ATOM   3657 N N   . ILE B 1 287 ? 133.981 149.485 134.162 1.00 45.45  ? 287 ILE B N   1 
ATOM   3658 C CA  . ILE B 1 287 ? 133.715 148.105 133.753 1.00 47.31  ? 287 ILE B CA  1 
ATOM   3659 C C   . ILE B 1 287 ? 132.614 148.061 132.698 1.00 52.42  ? 287 ILE B C   1 
ATOM   3660 O O   . ILE B 1 287 ? 132.717 147.337 131.700 1.00 57.01  ? 287 ILE B O   1 
ATOM   3661 C CB  . ILE B 1 287 ? 133.352 147.238 134.972 1.00 45.09  ? 287 ILE B CB  1 
ATOM   3662 C CG1 . ILE B 1 287 ? 134.517 147.161 135.956 1.00 47.61  ? 287 ILE B CG1 1 
ATOM   3663 C CG2 . ILE B 1 287 ? 132.962 145.847 134.531 1.00 41.56  ? 287 ILE B CG2 1 
ATOM   3664 C CD1 . ILE B 1 287 ? 134.218 146.335 137.184 1.00 43.67  ? 287 ILE B CD1 1 
ATOM   3665 N N   . ASN B 1 288 ? 131.545 148.835 132.904 1.00 48.72  ? 288 ASN B N   1 
ATOM   3666 C CA  . ASN B 1 288 ? 130.441 148.871 131.946 1.00 45.87  ? 288 ASN B CA  1 
ATOM   3667 C C   . ASN B 1 288 ? 130.896 149.371 130.583 1.00 51.46  ? 288 ASN B C   1 
ATOM   3668 O O   . ASN B 1 288 ? 130.485 148.833 129.549 1.00 55.25  ? 288 ASN B O   1 
ATOM   3669 C CB  . ASN B 1 288 ? 129.315 149.761 132.468 1.00 41.92  ? 288 ASN B CB  1 
ATOM   3670 C CG  . ASN B 1 288 ? 128.473 149.079 133.506 1.00 42.82  ? 288 ASN B CG  1 
ATOM   3671 O OD1 . ASN B 1 288 ? 128.127 147.913 133.365 1.00 49.47  ? 288 ASN B OD1 1 
ATOM   3672 N ND2 . ASN B 1 288 ? 128.136 149.802 134.561 1.00 43.47  ? 288 ASN B ND2 1 
ATOM   3673 N N   . THR B 1 289 ? 131.708 150.428 130.559 1.00 50.54  ? 289 THR B N   1 
ATOM   3674 C CA  . THR B 1 289 ? 132.175 150.967 129.286 1.00 50.28  ? 289 THR B CA  1 
ATOM   3675 C C   . THR B 1 289 ? 133.035 149.956 128.542 1.00 55.81  ? 289 THR B C   1 
ATOM   3676 O O   . THR B 1 289 ? 132.904 149.795 127.321 1.00 62.39  ? 289 THR B O   1 
ATOM   3677 C CB  . THR B 1 289 ? 132.945 152.259 129.519 1.00 48.36  ? 289 THR B CB  1 
ATOM   3678 O OG1 . THR B 1 289 ? 133.738 152.122 130.701 1.00 53.68  ? 289 THR B OG1 1 
ATOM   3679 C CG2 . THR B 1 289 ? 131.986 153.413 129.697 1.00 52.73  ? 289 THR B CG2 1 
ATOM   3680 N N   . TYR B 1 290 ? 133.916 149.258 129.263 1.00 54.97  ? 290 TYR B N   1 
ATOM   3681 C CA  . TYR B 1 290 ? 134.689 148.190 128.634 1.00 55.05  ? 290 TYR B CA  1 
ATOM   3682 C C   . TYR B 1 290 ? 133.774 147.109 128.074 1.00 56.88  ? 290 TYR B C   1 
ATOM   3683 O O   . TYR B 1 290 ? 133.990 146.612 126.960 1.00 62.65  ? 290 TYR B O   1 
ATOM   3684 C CB  . TYR B 1 290 ? 135.672 147.592 129.641 1.00 59.88  ? 290 TYR B CB  1 
ATOM   3685 C CG  . TYR B 1 290 ? 136.131 146.191 129.304 1.00 67.10  ? 290 TYR B CG  1 
ATOM   3686 C CD1 . TYR B 1 290 ? 137.166 145.975 128.407 1.00 66.63  ? 290 TYR B CD1 1 
ATOM   3687 C CD2 . TYR B 1 290 ? 135.533 145.085 129.892 1.00 70.40  ? 290 TYR B CD2 1 
ATOM   3688 C CE1 . TYR B 1 290 ? 137.588 144.699 128.103 1.00 67.49  ? 290 TYR B CE1 1 
ATOM   3689 C CE2 . TYR B 1 290 ? 135.946 143.809 129.590 1.00 67.62  ? 290 TYR B CE2 1 
ATOM   3690 C CZ  . TYR B 1 290 ? 136.971 143.621 128.696 1.00 69.08  ? 290 TYR B CZ  1 
ATOM   3691 O OH  . TYR B 1 290 ? 137.382 142.346 128.398 1.00 81.23  ? 290 TYR B OH  1 
ATOM   3692 N N   . GLY B 1 291 ? 132.746 146.730 128.836 1.00 54.41  ? 291 GLY B N   1 
ATOM   3693 C CA  . GLY B 1 291 ? 131.826 145.713 128.362 1.00 55.65  ? 291 GLY B CA  1 
ATOM   3694 C C   . GLY B 1 291 ? 131.094 146.126 127.102 1.00 61.34  ? 291 GLY B C   1 
ATOM   3695 O O   . GLY B 1 291 ? 130.954 145.334 126.169 1.00 65.90  ? 291 GLY B O   1 
ATOM   3696 N N   . TRP B 1 292 ? 130.618 147.373 127.056 1.00 60.94  ? 292 TRP B N   1 
ATOM   3697 C CA  . TRP B 1 292 ? 129.941 147.852 125.853 1.00 63.61  ? 292 TRP B CA  1 
ATOM   3698 C C   . TRP B 1 292 ? 130.888 147.867 124.665 1.00 64.81  ? 292 TRP B C   1 
ATOM   3699 O O   . TRP B 1 292 ? 130.512 147.466 123.558 1.00 66.88  ? 292 TRP B O   1 
ATOM   3700 C CB  . TRP B 1 292 ? 129.368 149.255 126.056 1.00 59.51  ? 292 TRP B CB  1 
ATOM   3701 C CG  . TRP B 1 292 ? 128.552 149.445 127.279 1.00 55.29  ? 292 TRP B CG  1 
ATOM   3702 C CD1 . TRP B 1 292 ? 127.856 148.497 127.958 1.00 53.78  ? 292 TRP B CD1 1 
ATOM   3703 C CD2 . TRP B 1 292 ? 128.357 150.672 127.982 1.00 54.66  ? 292 TRP B CD2 1 
ATOM   3704 N NE1 . TRP B 1 292 ? 127.235 149.057 129.044 1.00 54.88  ? 292 TRP B NE1 1 
ATOM   3705 C CE2 . TRP B 1 292 ? 127.529 150.394 129.080 1.00 54.80  ? 292 TRP B CE2 1 
ATOM   3706 C CE3 . TRP B 1 292 ? 128.804 151.980 127.789 1.00 55.33  ? 292 TRP B CE3 1 
ATOM   3707 C CZ2 . TRP B 1 292 ? 127.142 151.374 129.985 1.00 55.96  ? 292 TRP B CZ2 1 
ATOM   3708 C CZ3 . TRP B 1 292 ? 128.416 152.951 128.682 1.00 52.83  ? 292 TRP B CZ3 1 
ATOM   3709 C CH2 . TRP B 1 292 ? 127.594 152.646 129.767 1.00 54.06  ? 292 TRP B CH2 1 
ATOM   3710 N N   . ARG B 1 293 ? 132.120 148.337 124.871 1.00 63.00  ? 293 ARG B N   1 
ATOM   3711 C CA  . ARG B 1 293 ? 133.064 148.411 123.762 1.00 59.69  ? 293 ARG B CA  1 
ATOM   3712 C C   . ARG B 1 293 ? 133.381 147.027 123.214 1.00 61.70  ? 293 ARG B C   1 
ATOM   3713 O O   . ARG B 1 293 ? 133.472 146.841 121.995 1.00 65.58  ? 293 ARG B O   1 
ATOM   3714 C CB  . ARG B 1 293 ? 134.339 149.126 124.204 1.00 59.40  ? 293 ARG B CB  1 
ATOM   3715 C CG  . ARG B 1 293 ? 135.444 149.123 123.163 1.00 66.22  ? 293 ARG B CG  1 
ATOM   3716 C CD  . ARG B 1 293 ? 136.419 150.271 123.377 1.00 71.14  ? 293 ARG B CD  1 
ATOM   3717 N NE  . ARG B 1 293 ? 135.880 151.546 122.914 1.00 81.38  ? 293 ARG B NE  1 
ATOM   3718 C CZ  . ARG B 1 293 ? 135.272 152.435 123.688 1.00 80.66  ? 293 ARG B CZ  1 
ATOM   3719 N NH1 . ARG B 1 293 ? 135.109 152.228 124.984 1.00 80.27  ? 293 ARG B NH1 1 
ATOM   3720 N NH2 . ARG B 1 293 ? 134.819 153.562 123.148 1.00 78.88  ? 293 ARG B NH2 1 
ATOM   3721 N N   . GLN B 1 294 ? 133.547 146.038 124.096 1.00 62.45  ? 294 GLN B N   1 
ATOM   3722 C CA  . GLN B 1 294 ? 133.856 144.689 123.630 1.00 64.34  ? 294 GLN B CA  1 
ATOM   3723 C C   . GLN B 1 294 ? 132.640 143.972 123.059 1.00 68.11  ? 294 GLN B C   1 
ATOM   3724 O O   . GLN B 1 294 ? 132.794 143.073 122.226 1.00 72.07  ? 294 GLN B O   1 
ATOM   3725 C CB  . GLN B 1 294 ? 134.455 143.858 124.763 1.00 63.72  ? 294 GLN B CB  1 
ATOM   3726 C CG  . GLN B 1 294 ? 135.799 144.360 125.236 1.00 67.93  ? 294 GLN B CG  1 
ATOM   3727 C CD  . GLN B 1 294 ? 136.846 144.347 124.146 1.00 66.68  ? 294 GLN B CD  1 
ATOM   3728 O OE1 . GLN B 1 294 ? 136.842 143.479 123.274 1.00 73.54  ? 294 GLN B OE1 1 
ATOM   3729 N NE2 . GLN B 1 294 ? 137.752 145.315 124.188 1.00 59.52  ? 294 GLN B NE2 1 
ATOM   3730 N N   . ALA B 1 295 ? 131.436 144.338 123.493 1.00 66.27  ? 295 ALA B N   1 
ATOM   3731 C CA  . ALA B 1 295 ? 130.234 143.647 123.050 1.00 63.50  ? 295 ALA B CA  1 
ATOM   3732 C C   . ALA B 1 295 ? 129.653 144.220 121.769 1.00 64.77  ? 295 ALA B C   1 
ATOM   3733 O O   . ALA B 1 295 ? 128.613 143.737 121.313 1.00 69.70  ? 295 ALA B O   1 
ATOM   3734 C CB  . ALA B 1 295 ? 129.174 143.682 124.150 1.00 62.06  ? 295 ALA B CB  1 
ATOM   3735 N N   . GLY B 1 296 ? 130.286 145.229 121.181 1.00 66.08  ? 296 GLY B N   1 
ATOM   3736 C CA  . GLY B 1 296 ? 129.776 145.852 119.981 1.00 68.41  ? 296 GLY B CA  1 
ATOM   3737 C C   . GLY B 1 296 ? 128.742 146.929 120.211 1.00 72.04  ? 296 GLY B C   1 
ATOM   3738 O O   . GLY B 1 296 ? 128.249 147.507 119.236 1.00 72.11  ? 296 GLY B O   1 
ATOM   3739 N N   . VAL B 1 297 ? 128.402 147.220 121.464 1.00 72.28  ? 297 VAL B N   1 
ATOM   3740 C CA  . VAL B 1 297 ? 127.428 148.262 121.764 1.00 73.02  ? 297 VAL B CA  1 
ATOM   3741 C C   . VAL B 1 297 ? 128.029 149.616 121.413 1.00 76.33  ? 297 VAL B C   1 
ATOM   3742 O O   . VAL B 1 297 ? 129.075 150.005 121.944 1.00 77.43  ? 297 VAL B O   1 
ATOM   3743 C CB  . VAL B 1 297 ? 127.007 148.209 123.236 1.00 70.07  ? 297 VAL B CB  1 
ATOM   3744 C CG1 . VAL B 1 297 ? 126.189 149.430 123.591 1.00 71.03  ? 297 VAL B CG1 1 
ATOM   3745 C CG2 . VAL B 1 297 ? 126.222 146.943 123.511 1.00 72.50  ? 297 VAL B CG2 1 
ATOM   3746 N N   . ASN B 1 298 ? 127.366 150.343 120.517 1.00 74.29  ? 298 ASN B N   1 
ATOM   3747 C CA  . ASN B 1 298 ? 127.831 151.667 120.109 1.00 73.50  ? 298 ASN B CA  1 
ATOM   3748 C C   . ASN B 1 298 ? 127.280 152.709 121.080 1.00 77.29  ? 298 ASN B C   1 
ATOM   3749 O O   . ASN B 1 298 ? 126.427 153.532 120.751 1.00 83.94  ? 298 ASN B O   1 
ATOM   3750 C CB  . ASN B 1 298 ? 127.414 151.958 118.673 1.00 76.81  ? 298 ASN B CB  1 
ATOM   3751 C CG  . ASN B 1 298 ? 128.105 153.182 118.097 1.00 82.86  ? 298 ASN B CG  1 
ATOM   3752 O OD1 . ASN B 1 298 ? 128.408 154.139 118.810 1.00 82.36  ? 298 ASN B OD1 1 
ATOM   3753 N ND2 . ASN B 1 298 ? 128.359 153.153 116.795 1.00 88.16  ? 298 ASN B ND2 1 
ATOM   3754 N N   . HIS B 1 299 ? 127.798 152.658 122.308 1.00 77.36  ? 299 HIS B N   1 
ATOM   3755 C CA  . HIS B 1 299 ? 127.380 153.618 123.321 1.00 78.12  ? 299 HIS B CA  1 
ATOM   3756 C C   . HIS B 1 299 ? 127.794 155.040 122.971 1.00 82.09  ? 299 HIS B C   1 
ATOM   3757 O O   . HIS B 1 299 ? 127.293 155.986 123.585 1.00 82.39  ? 299 HIS B O   1 
ATOM   3758 C CB  . HIS B 1 299 ? 127.948 153.231 124.686 1.00 70.59  ? 299 HIS B CB  1 
ATOM   3759 C CG  . HIS B 1 299 ? 129.419 153.472 124.824 1.00 75.11  ? 299 HIS B CG  1 
ATOM   3760 N ND1 . HIS B 1 299 ? 129.944 154.702 125.154 1.00 81.28  ? 299 HIS B ND1 1 
ATOM   3761 C CD2 . HIS B 1 299 ? 130.476 152.637 124.685 1.00 75.39  ? 299 HIS B CD2 1 
ATOM   3762 C CE1 . HIS B 1 299 ? 131.261 154.617 125.207 1.00 79.12  ? 299 HIS B CE1 1 
ATOM   3763 N NE2 . HIS B 1 299 ? 131.609 153.374 124.927 1.00 79.18  ? 299 HIS B NE2 1 
ATOM   3764 N N   . VAL B 1 300 ? 128.706 155.210 122.014 1.00 80.01  ? 300 VAL B N   1 
ATOM   3765 C CA  . VAL B 1 300 ? 129.064 156.550 121.562 1.00 81.95  ? 300 VAL B CA  1 
ATOM   3766 C C   . VAL B 1 300 ? 127.869 157.221 120.898 1.00 85.94  ? 300 VAL B C   1 
ATOM   3767 O O   . VAL B 1 300 ? 127.540 158.376 121.191 1.00 88.13  ? 300 VAL B O   1 
ATOM   3768 C CB  . VAL B 1 300 ? 130.273 156.487 120.613 1.00 81.74  ? 300 VAL B CB  1 
ATOM   3769 C CG1 . VAL B 1 300 ? 130.640 157.877 120.132 1.00 87.25  ? 300 VAL B CG1 1 
ATOM   3770 C CG2 . VAL B 1 300 ? 131.453 155.829 121.302 1.00 86.69  ? 300 VAL B CG2 1 
ATOM   3771 N N   . LEU B 1 301 ? 127.197 156.505 119.996 1.00 85.87  ? 301 LEU B N   1 
ATOM   3772 C CA  . LEU B 1 301 ? 126.044 157.076 119.310 1.00 87.52  ? 301 LEU B CA  1 
ATOM   3773 C C   . LEU B 1 301 ? 124.809 157.087 120.199 1.00 84.52  ? 301 LEU B C   1 
ATOM   3774 O O   . LEU B 1 301 ? 123.982 158.000 120.099 1.00 86.09  ? 301 LEU B O   1 
ATOM   3775 C CB  . LEU B 1 301 ? 125.765 156.310 118.018 1.00 86.71  ? 301 LEU B CB  1 
ATOM   3776 C CG  . LEU B 1 301 ? 124.645 156.881 117.147 1.00 87.80  ? 301 LEU B CG  1 
ATOM   3777 C CD1 . LEU B 1 301 ? 124.886 158.354 116.863 1.00 87.09  ? 301 LEU B CD1 1 
ATOM   3778 C CD2 . LEU B 1 301 ? 124.518 156.099 115.851 1.00 93.52  ? 301 LEU B CD2 1 
ATOM   3779 N N   . ILE B 1 302 ? 124.661 156.084 121.066 1.00 83.23  ? 302 ILE B N   1 
ATOM   3780 C CA  . ILE B 1 302 ? 123.492 156.028 121.939 1.00 82.33  ? 302 ILE B CA  1 
ATOM   3781 C C   . ILE B 1 302 ? 123.471 157.226 122.876 1.00 84.73  ? 302 ILE B C   1 
ATOM   3782 O O   . ILE B 1 302 ? 122.436 157.882 123.048 1.00 90.29  ? 302 ILE B O   1 
ATOM   3783 C CB  . ILE B 1 302 ? 123.464 154.703 122.720 1.00 72.01  ? 302 ILE B CB  1 
ATOM   3784 C CG1 . ILE B 1 302 ? 123.301 153.523 121.770 1.00 69.94  ? 302 ILE B CG1 1 
ATOM   3785 C CG2 . ILE B 1 302 ? 122.329 154.702 123.709 1.00 68.49  ? 302 ILE B CG2 1 
ATOM   3786 C CD1 . ILE B 1 302 ? 123.177 152.208 122.480 1.00 70.22  ? 302 ILE B CD1 1 
ATOM   3787 N N   . PHE B 1 303 ? 124.612 157.546 123.479 1.00 78.86  ? 303 PHE B N   1 
ATOM   3788 C CA  . PHE B 1 303 ? 124.699 158.642 124.433 1.00 78.80  ? 303 PHE B CA  1 
ATOM   3789 C C   . PHE B 1 303 ? 124.699 160.015 123.778 1.00 86.86  ? 303 PHE B C   1 
ATOM   3790 O O   . PHE B 1 303 ? 124.876 161.012 124.486 1.00 85.66  ? 303 PHE B O   1 
ATOM   3791 C CB  . PHE B 1 303 ? 125.958 158.495 125.287 1.00 77.70  ? 303 PHE B CB  1 
ATOM   3792 C CG  . PHE B 1 303 ? 125.769 157.648 126.503 1.00 66.36  ? 303 PHE B CG  1 
ATOM   3793 C CD1 . PHE B 1 303 ? 125.180 158.172 127.632 1.00 56.35  ? 303 PHE B CD1 1 
ATOM   3794 C CD2 . PHE B 1 303 ? 126.186 156.334 126.521 1.00 63.87  ? 303 PHE B CD2 1 
ATOM   3795 C CE1 . PHE B 1 303 ? 125.005 157.404 128.748 1.00 50.59  ? 303 PHE B CE1 1 
ATOM   3796 C CE2 . PHE B 1 303 ? 126.011 155.562 127.640 1.00 57.13  ? 303 PHE B CE2 1 
ATOM   3797 C CZ  . PHE B 1 303 ? 125.418 156.099 128.754 1.00 51.70  ? 303 PHE B CZ  1 
ATOM   3798 N N   . GLU B 1 304 ? 124.506 160.091 122.460 1.00 87.57  ? 304 GLU B N   1 
ATOM   3799 C CA  . GLU B 1 304 ? 124.633 161.344 121.717 1.00 91.91  ? 304 GLU B CA  1 
ATOM   3800 C C   . GLU B 1 304 ? 126.000 161.973 121.967 1.00 96.03  ? 304 GLU B C   1 
ATOM   3801 O O   . GLU B 1 304 ? 126.137 163.189 122.109 1.00 97.94  ? 304 GLU B O   1 
ATOM   3802 C CB  . GLU B 1 304 ? 123.504 162.317 122.067 1.00 94.93  ? 304 GLU B CB  1 
ATOM   3803 C CG  . GLU B 1 304 ? 122.126 161.675 122.143 1.00 93.76  ? 304 GLU B CG  1 
ATOM   3804 C CD  . GLU B 1 304 ? 121.693 161.048 120.832 1.00 98.69  ? 304 GLU B CD  1 
ATOM   3805 O OE1 . GLU B 1 304 ? 122.107 161.545 119.763 1.00 104.20 ? 304 GLU B OE1 1 
ATOM   3806 O OE2 . GLU B 1 304 ? 120.937 160.054 120.872 1.00 96.06  ? 304 GLU B OE2 1 
ATOM   3807 N N   . LEU B 1 305 ? 127.021 161.126 122.019 1.00 97.23  ? 305 LEU B N   1 
ATOM   3808 C CA  . LEU B 1 305 ? 128.368 161.528 122.390 1.00 95.23  ? 305 LEU B CA  1 
ATOM   3809 C C   . LEU B 1 305 ? 129.190 161.807 121.141 1.00 100.07 ? 305 LEU B C   1 
ATOM   3810 O O   . LEU B 1 305 ? 129.109 161.070 120.154 1.00 100.08 ? 305 LEU B O   1 
ATOM   3811 C CB  . LEU B 1 305 ? 129.040 160.442 123.229 1.00 89.27  ? 305 LEU B CB  1 
ATOM   3812 C CG  . LEU B 1 305 ? 129.884 160.906 124.410 1.00 88.69  ? 305 LEU B CG  1 
ATOM   3813 C CD1 . LEU B 1 305 ? 129.179 162.031 125.132 1.00 81.11  ? 305 LEU B CD1 1 
ATOM   3814 C CD2 . LEU B 1 305 ? 130.141 159.748 125.359 1.00 81.57  ? 305 LEU B CD2 1 
ATOM   3815 N N   . ASN B 1 306 ? 129.971 162.878 121.189 1.00 106.42 ? 306 ASN B N   1 
ATOM   3816 C CA  . ASN B 1 306 ? 130.790 163.251 120.048 1.00 112.33 ? 306 ASN B CA  1 
ATOM   3817 C C   . ASN B 1 306 ? 131.878 162.203 119.822 1.00 114.77 ? 306 ASN B C   1 
ATOM   3818 O O   . ASN B 1 306 ? 132.397 161.628 120.784 1.00 115.49 ? 306 ASN B O   1 
ATOM   3819 C CB  . ASN B 1 306 ? 131.420 164.625 120.272 1.00 112.77 ? 306 ASN B CB  1 
ATOM   3820 C CG  . ASN B 1 306 ? 132.121 165.156 119.039 1.00 119.95 ? 306 ASN B CG  1 
ATOM   3821 O OD1 . ASN B 1 306 ? 133.226 164.730 118.707 1.00 121.40 ? 306 ASN B OD1 1 
ATOM   3822 N ND2 . ASN B 1 306 ? 131.481 166.096 118.354 1.00 123.00 ? 306 ASN B ND2 1 
ATOM   3823 N N   . PRO B 1 307 ? 132.231 161.920 118.566 1.00 118.80 ? 307 PRO B N   1 
ATOM   3824 C CA  . PRO B 1 307 ? 133.324 160.968 118.316 1.00 122.68 ? 307 PRO B CA  1 
ATOM   3825 C C   . PRO B 1 307 ? 134.649 161.392 118.923 1.00 122.67 ? 307 PRO B C   1 
ATOM   3826 O O   . PRO B 1 307 ? 135.482 160.530 119.229 1.00 116.28 ? 307 PRO B O   1 
ATOM   3827 C CB  . PRO B 1 307 ? 133.391 160.913 116.784 1.00 123.65 ? 307 PRO B CB  1 
ATOM   3828 C CG  . PRO B 1 307 ? 132.012 161.271 116.344 1.00 120.63 ? 307 PRO B CG  1 
ATOM   3829 C CD  . PRO B 1 307 ? 131.531 162.297 117.327 1.00 118.10 ? 307 PRO B CD  1 
ATOM   3830 N N   . ARG B 1 308 ? 134.875 162.691 119.108 1.00 124.17 ? 308 ARG B N   1 
ATOM   3831 C CA  . ARG B 1 308 ? 136.098 163.144 119.750 1.00 121.43 ? 308 ARG B CA  1 
ATOM   3832 C C   . ARG B 1 308 ? 136.076 162.796 121.238 1.00 119.78 ? 308 ARG B C   1 
ATOM   3833 O O   . ARG B 1 308 ? 135.044 162.427 121.806 1.00 117.75 ? 308 ARG B O   1 
ATOM   3834 C CB  . ARG B 1 308 ? 136.281 164.649 119.558 1.00 123.38 ? 308 ARG B CB  1 
ATOM   3835 C CG  . ARG B 1 308 ? 136.470 165.073 118.114 1.00 126.25 ? 308 ARG B CG  1 
ATOM   3836 C CD  . ARG B 1 308 ? 136.606 166.583 117.996 1.00 136.11 ? 308 ARG B CD  1 
ATOM   3837 N NE  . ARG B 1 308 ? 135.405 167.278 118.444 1.00 138.65 ? 308 ARG B NE  1 
ATOM   3838 C CZ  . ARG B 1 308 ? 135.236 168.593 118.392 1.00 142.83 ? 308 ARG B CZ  1 
ATOM   3839 N NH1 . ARG B 1 308 ? 136.177 169.393 117.920 1.00 145.75 ? 308 ARG B NH1 1 
ATOM   3840 N NH2 . ARG B 1 308 ? 134.092 169.117 118.823 1.00 141.88 ? 308 ARG B NH2 1 
ATOM   3841 N N   . SER B 1 309 ? 137.247 162.920 121.867 1.00 117.53 ? 309 SER B N   1 
ATOM   3842 C CA  . SER B 1 309 ? 137.429 162.588 123.276 1.00 111.27 ? 309 SER B CA  1 
ATOM   3843 C C   . SER B 1 309 ? 137.009 161.150 123.546 1.00 107.24 ? 309 SER B C   1 
ATOM   3844 O O   . SER B 1 309 ? 137.733 160.215 123.190 1.00 107.64 ? 309 SER B O   1 
ATOM   3845 C CB  . SER B 1 309 ? 136.647 163.556 124.164 1.00 106.69 ? 309 SER B CB  1 
ATOM   3846 O OG  . SER B 1 309 ? 137.016 164.894 123.890 1.00 103.65 ? 309 SER B OG  1 
ATOM   3847 N N   . ASN B 1 310 ? 135.841 160.965 124.169 1.00 102.27 ? 310 ASN B N   1 
ATOM   3848 C CA  . ASN B 1 310 ? 135.271 159.640 124.411 1.00 98.00  ? 310 ASN B CA  1 
ATOM   3849 C C   . ASN B 1 310 ? 136.245 158.772 125.215 1.00 96.66  ? 310 ASN B C   1 
ATOM   3850 O O   . ASN B 1 310 ? 136.831 157.807 124.718 1.00 98.76  ? 310 ASN B O   1 
ATOM   3851 C CB  . ASN B 1 310 ? 134.878 158.972 123.087 1.00 102.81 ? 310 ASN B CB  1 
ATOM   3852 C CG  . ASN B 1 310 ? 134.320 157.577 123.279 1.00 103.16 ? 310 ASN B CG  1 
ATOM   3853 O OD1 . ASN B 1 310 ? 133.726 157.270 124.312 1.00 92.67  ? 310 ASN B OD1 1 
ATOM   3854 N ND2 . ASN B 1 310 ? 134.519 156.720 122.286 1.00 111.27 ? 310 ASN B ND2 1 
ATOM   3855 N N   . LEU B 1 311 ? 136.434 159.177 126.470 1.00 89.39  ? 311 LEU B N   1 
ATOM   3856 C CA  . LEU B 1 311 ? 137.367 158.478 127.342 1.00 84.47  ? 311 LEU B CA  1 
ATOM   3857 C C   . LEU B 1 311 ? 137.001 157.003 127.456 1.00 82.65  ? 311 LEU B C   1 
ATOM   3858 O O   . LEU B 1 311 ? 135.827 156.641 127.563 1.00 82.94  ? 311 LEU B O   1 
ATOM   3859 C CB  . LEU B 1 311 ? 137.402 159.133 128.727 1.00 75.95  ? 311 LEU B CB  1 
ATOM   3860 C CG  . LEU B 1 311 ? 136.129 159.423 129.526 1.00 71.13  ? 311 LEU B CG  1 
ATOM   3861 C CD1 . LEU B 1 311 ? 135.598 158.192 130.231 1.00 64.91  ? 311 LEU B CD1 1 
ATOM   3862 C CD2 . LEU B 1 311 ? 136.414 160.509 130.537 1.00 71.12  ? 311 LEU B CD2 1 
ATOM   3863 N N   . SER B 1 312 ? 138.020 156.150 127.405 1.00 80.13  ? 312 SER B N   1 
ATOM   3864 C CA  . SER B 1 312 ? 137.826 154.713 127.483 1.00 73.85  ? 312 SER B CA  1 
ATOM   3865 C C   . SER B 1 312 ? 137.720 154.276 128.942 1.00 66.56  ? 312 SER B C   1 
ATOM   3866 O O   . SER B 1 312 ? 137.721 155.091 129.867 1.00 65.02  ? 312 SER B O   1 
ATOM   3867 C CB  . SER B 1 312 ? 138.962 153.989 126.766 1.00 72.64  ? 312 SER B CB  1 
ATOM   3868 O OG  . SER B 1 312 ? 140.218 154.360 127.304 1.00 64.98  ? 312 SER B OG  1 
ATOM   3869 N N   . HIS B 1 313 ? 137.629 152.960 129.149 1.00 61.41  ? 313 HIS B N   1 
ATOM   3870 C CA  . HIS B 1 313 ? 137.455 152.429 130.497 1.00 61.39  ? 313 HIS B CA  1 
ATOM   3871 C C   . HIS B 1 313 ? 138.653 152.723 131.386 1.00 60.57  ? 313 HIS B C   1 
ATOM   3872 O O   . HIS B 1 313 ? 138.500 152.887 132.602 1.00 58.41  ? 313 HIS B O   1 
ATOM   3873 C CB  . HIS B 1 313 ? 137.204 150.925 130.433 1.00 59.29  ? 313 HIS B CB  1 
ATOM   3874 C CG  . HIS B 1 313 ? 138.162 150.189 129.551 1.00 60.99  ? 313 HIS B CG  1 
ATOM   3875 N ND1 . HIS B 1 313 ? 138.086 150.225 128.176 1.00 62.83  ? 313 HIS B ND1 1 
ATOM   3876 C CD2 . HIS B 1 313 ? 139.208 149.384 129.849 1.00 64.76  ? 313 HIS B CD2 1 
ATOM   3877 C CE1 . HIS B 1 313 ? 139.049 149.481 127.665 1.00 69.98  ? 313 HIS B CE1 1 
ATOM   3878 N NE2 . HIS B 1 313 ? 139.744 148.959 128.659 1.00 71.80  ? 313 HIS B NE2 1 
ATOM   3879 N N   . GLN B 1 314 ? 139.849 152.796 130.801 1.00 61.58  ? 314 GLN B N   1 
ATOM   3880 C CA  . GLN B 1 314 ? 141.047 153.040 131.595 1.00 58.46  ? 314 GLN B CA  1 
ATOM   3881 C C   . GLN B 1 314 ? 140.987 154.396 132.282 1.00 58.43  ? 314 GLN B C   1 
ATOM   3882 O O   . GLN B 1 314 ? 141.429 154.538 133.424 1.00 54.74  ? 314 GLN B O   1 
ATOM   3883 C CB  . GLN B 1 314 ? 142.285 152.940 130.709 1.00 57.51  ? 314 GLN B CB  1 
ATOM   3884 C CG  . GLN B 1 314 ? 142.436 151.598 130.036 1.00 62.95  ? 314 GLN B CG  1 
ATOM   3885 C CD  . GLN B 1 314 ? 143.021 151.722 128.651 1.00 68.73  ? 314 GLN B CD  1 
ATOM   3886 O OE1 . GLN B 1 314 ? 143.278 152.825 128.177 1.00 68.93  ? 314 GLN B OE1 1 
ATOM   3887 N NE2 . GLN B 1 314 ? 143.229 150.591 127.990 1.00 73.17  ? 314 GLN B NE2 1 
ATOM   3888 N N   . HIS B 1 315 ? 140.452 155.409 131.598 1.00 60.13  ? 315 HIS B N   1 
ATOM   3889 C CA  . HIS B 1 315 ? 140.362 156.734 132.203 1.00 60.00  ? 315 HIS B CA  1 
ATOM   3890 C C   . HIS B 1 315 ? 139.418 156.733 133.399 1.00 57.34  ? 315 HIS B C   1 
ATOM   3891 O O   . HIS B 1 315 ? 139.707 157.354 134.429 1.00 58.62  ? 315 HIS B O   1 
ATOM   3892 C CB  . HIS B 1 315 ? 139.920 157.752 131.156 1.00 60.89  ? 315 HIS B CB  1 
ATOM   3893 C CG  . HIS B 1 315 ? 140.832 157.828 129.972 1.00 64.32  ? 315 HIS B CG  1 
ATOM   3894 N ND1 . HIS B 1 315 ? 140.972 156.794 129.073 1.00 65.92  ? 315 HIS B ND1 1 
ATOM   3895 C CD2 . HIS B 1 315 ? 141.655 158.813 129.543 1.00 64.23  ? 315 HIS B CD2 1 
ATOM   3896 C CE1 . HIS B 1 315 ? 141.838 157.141 128.138 1.00 64.46  ? 315 HIS B CE1 1 
ATOM   3897 N NE2 . HIS B 1 315 ? 142.268 158.361 128.400 1.00 61.12  ? 315 HIS B NE2 1 
ATOM   3898 N N   . LEU B 1 316 ? 138.287 156.035 133.286 1.00 51.00  ? 316 LEU B N   1 
ATOM   3899 C CA  . LEU B 1 316 ? 137.385 155.903 134.425 1.00 49.49  ? 316 LEU B CA  1 
ATOM   3900 C C   . LEU B 1 316 ? 138.050 155.152 135.571 1.00 51.33  ? 316 LEU B C   1 
ATOM   3901 O O   . LEU B 1 316 ? 137.886 155.517 136.741 1.00 48.59  ? 316 LEU B O   1 
ATOM   3902 C CB  . LEU B 1 316 ? 136.097 155.205 133.994 1.00 45.67  ? 316 LEU B CB  1 
ATOM   3903 C CG  . LEU B 1 316 ? 135.043 156.103 133.351 1.00 44.23  ? 316 LEU B CG  1 
ATOM   3904 C CD1 . LEU B 1 316 ? 134.008 155.269 132.638 1.00 49.05  ? 316 LEU B CD1 1 
ATOM   3905 C CD2 . LEU B 1 316 ? 134.390 156.966 134.411 1.00 39.41  ? 316 LEU B CD2 1 
ATOM   3906 N N   . PHE B 1 317 ? 138.810 154.101 135.253 1.00 51.03  ? 317 PHE B N   1 
ATOM   3907 C CA  . PHE B 1 317 ? 139.539 153.381 136.293 1.00 48.36  ? 317 PHE B CA  1 
ATOM   3908 C C   . PHE B 1 317 ? 140.557 154.283 136.980 1.00 54.03  ? 317 PHE B C   1 
ATOM   3909 O O   . PHE B 1 317 ? 140.738 154.209 138.199 1.00 56.11  ? 317 PHE B O   1 
ATOM   3910 C CB  . PHE B 1 317 ? 140.226 152.154 135.701 1.00 48.42  ? 317 PHE B CB  1 
ATOM   3911 C CG  . PHE B 1 317 ? 139.279 151.076 135.279 1.00 49.97  ? 317 PHE B CG  1 
ATOM   3912 C CD1 . PHE B 1 317 ? 138.153 150.803 136.020 1.00 46.97  ? 317 PHE B CD1 1 
ATOM   3913 C CD2 . PHE B 1 317 ? 139.516 150.337 134.140 1.00 56.00  ? 317 PHE B CD2 1 
ATOM   3914 C CE1 . PHE B 1 317 ? 137.282 149.812 135.634 1.00 45.93  ? 317 PHE B CE1 1 
ATOM   3915 C CE2 . PHE B 1 317 ? 138.647 149.346 133.749 1.00 52.37  ? 317 PHE B CE2 1 
ATOM   3916 C CZ  . PHE B 1 317 ? 137.529 149.085 134.498 1.00 49.35  ? 317 PHE B CZ  1 
ATOM   3917 N N   . GLU B 1 318 ? 141.233 155.139 136.210 1.00 55.29  ? 318 GLU B N   1 
ATOM   3918 C CA  . GLU B 1 318 ? 142.206 156.067 136.781 1.00 51.32  ? 318 GLU B CA  1 
ATOM   3919 C C   . GLU B 1 318 ? 141.540 157.090 137.694 1.00 52.48  ? 318 GLU B C   1 
ATOM   3920 O O   . GLU B 1 318 ? 142.050 157.382 138.785 1.00 49.41  ? 318 GLU B O   1 
ATOM   3921 C CB  . GLU B 1 318 ? 142.967 156.774 135.662 1.00 48.60  ? 318 GLU B CB  1 
ATOM   3922 C CG  . GLU B 1 318 ? 143.921 157.844 136.151 1.00 53.34  ? 318 GLU B CG  1 
ATOM   3923 C CD  . GLU B 1 318 ? 144.517 158.654 135.022 1.00 60.51  ? 318 GLU B CD  1 
ATOM   3924 O OE1 . GLU B 1 318 ? 144.270 158.308 133.849 1.00 62.38  ? 318 GLU B OE1 1 
ATOM   3925 O OE2 . GLU B 1 318 ? 145.229 159.638 135.308 1.00 56.70  ? 318 GLU B OE2 1 
ATOM   3926 N N   . ILE B 1 319 ? 140.407 157.654 137.264 1.00 53.63  ? 319 ILE B N   1 
ATOM   3927 C CA  . ILE B 1 319 ? 139.688 158.606 138.109 1.00 52.31  ? 319 ILE B CA  1 
ATOM   3928 C C   . ILE B 1 319 ? 139.228 157.932 139.391 1.00 53.76  ? 319 ILE B C   1 
ATOM   3929 O O   . ILE B 1 319 ? 139.362 158.489 140.489 1.00 54.57  ? 319 ILE B O   1 
ATOM   3930 C CB  . ILE B 1 319 ? 138.498 159.221 137.351 1.00 46.10  ? 319 ILE B CB  1 
ATOM   3931 C CG1 . ILE B 1 319 ? 138.959 159.872 136.056 1.00 55.45  ? 319 ILE B CG1 1 
ATOM   3932 C CG2 . ILE B 1 319 ? 137.812 160.254 138.211 1.00 46.04  ? 319 ILE B CG2 1 
ATOM   3933 C CD1 . ILE B 1 319 ? 137.822 160.364 135.196 1.00 55.40  ? 319 ILE B CD1 1 
ATOM   3934 N N   . ALA B 1 320 ? 138.673 156.724 139.272 1.00 50.37  ? 320 ALA B N   1 
ATOM   3935 C CA  . ALA B 1 320 ? 138.223 155.997 140.452 1.00 48.41  ? 320 ALA B CA  1 
ATOM   3936 C C   . ALA B 1 320 ? 139.382 155.705 141.391 1.00 49.27  ? 320 ALA B C   1 
ATOM   3937 O O   . ALA B 1 320 ? 139.249 155.846 142.609 1.00 48.31  ? 320 ALA B O   1 
ATOM   3938 C CB  . ALA B 1 320 ? 137.532 154.703 140.035 1.00 48.74  ? 320 ALA B CB  1 
ATOM   3939 N N   . GLY B 1 321 ? 140.533 155.310 140.844 1.00 51.66  ? 321 GLY B N   1 
ATOM   3940 C CA  . GLY B 1 321 ? 141.683 155.037 141.684 1.00 51.79  ? 321 GLY B CA  1 
ATOM   3941 C C   . GLY B 1 321 ? 142.186 156.269 142.409 1.00 52.84  ? 321 GLY B C   1 
ATOM   3942 O O   . GLY B 1 321 ? 142.503 156.211 143.596 1.00 53.03  ? 321 GLY B O   1 
ATOM   3943 N N   . PHE B 1 322 ? 142.263 157.401 141.708 1.00 50.42  ? 322 PHE B N   1 
ATOM   3944 C CA  . PHE B 1 322 ? 142.741 158.624 142.347 1.00 51.76  ? 322 PHE B CA  1 
ATOM   3945 C C   . PHE B 1 322 ? 141.783 159.087 143.441 1.00 58.09  ? 322 PHE B C   1 
ATOM   3946 O O   . PHE B 1 322 ? 142.207 159.422 144.560 1.00 62.85  ? 322 PHE B O   1 
ATOM   3947 C CB  . PHE B 1 322 ? 142.934 159.713 141.296 1.00 50.33  ? 322 PHE B CB  1 
ATOM   3948 C CG  . PHE B 1 322 ? 143.477 160.994 141.847 1.00 53.52  ? 322 PHE B CG  1 
ATOM   3949 C CD1 . PHE B 1 322 ? 144.817 161.116 142.152 1.00 56.03  ? 322 PHE B CD1 1 
ATOM   3950 C CD2 . PHE B 1 322 ? 142.647 162.076 142.059 1.00 54.81  ? 322 PHE B CD2 1 
ATOM   3951 C CE1 . PHE B 1 322 ? 145.318 162.292 142.658 1.00 61.52  ? 322 PHE B CE1 1 
ATOM   3952 C CE2 . PHE B 1 322 ? 143.146 163.253 142.566 1.00 56.83  ? 322 PHE B CE2 1 
ATOM   3953 C CZ  . PHE B 1 322 ? 144.482 163.360 142.864 1.00 60.33  ? 322 PHE B CZ  1 
ATOM   3954 N N   . LEU B 1 323 ? 140.481 159.099 143.143 1.00 56.37  ? 323 LEU B N   1 
ATOM   3955 C CA  . LEU B 1 323 ? 139.506 159.483 144.156 1.00 55.93  ? 323 LEU B CA  1 
ATOM   3956 C C   . LEU B 1 323 ? 139.530 158.515 145.328 1.00 51.12  ? 323 LEU B C   1 
ATOM   3957 O O   . LEU B 1 323 ? 139.370 158.924 146.483 1.00 48.75  ? 323 LEU B O   1 
ATOM   3958 C CB  . LEU B 1 323 ? 138.110 159.555 143.544 1.00 54.65  ? 323 LEU B CB  1 
ATOM   3959 C CG  . LEU B 1 323 ? 137.891 160.653 142.506 1.00 54.93  ? 323 LEU B CG  1 
ATOM   3960 C CD1 . LEU B 1 323 ? 136.470 160.607 141.993 1.00 49.77  ? 323 LEU B CD1 1 
ATOM   3961 C CD2 . LEU B 1 323 ? 138.204 162.013 143.097 1.00 65.19  ? 323 LEU B CD2 1 
ATOM   3962 N N   . GLY B 1 324 ? 139.731 157.227 145.054 1.00 50.03  ? 324 GLY B N   1 
ATOM   3963 C CA  . GLY B 1 324 ? 139.814 156.259 146.129 1.00 51.26  ? 324 GLY B CA  1 
ATOM   3964 C C   . GLY B 1 324 ? 141.048 156.438 146.987 1.00 52.45  ? 324 GLY B C   1 
ATOM   3965 O O   . GLY B 1 324 ? 141.007 156.210 148.195 1.00 54.74  ? 324 GLY B O   1 
ATOM   3966 N N   . ILE B 1 325 ? 142.166 156.825 146.375 1.00 51.03  ? 325 ILE B N   1 
ATOM   3967 C CA  . ILE B 1 325 ? 143.357 157.124 147.160 1.00 51.64  ? 325 ILE B CA  1 
ATOM   3968 C C   . ILE B 1 325 ? 143.088 158.294 148.086 1.00 55.97  ? 325 ILE B C   1 
ATOM   3969 O O   . ILE B 1 325 ? 143.439 158.259 149.271 1.00 57.38  ? 325 ILE B O   1 
ATOM   3970 C CB  . ILE B 1 325 ? 144.558 157.397 146.240 1.00 48.16  ? 325 ILE B CB  1 
ATOM   3971 C CG1 . ILE B 1 325 ? 144.992 156.118 145.545 1.00 49.36  ? 325 ILE B CG1 1 
ATOM   3972 C CG2 . ILE B 1 325 ? 145.720 157.965 147.028 1.00 46.50  ? 325 ILE B CG2 1 
ATOM   3973 C CD1 . ILE B 1 325 ? 146.128 156.336 144.607 1.00 48.61  ? 325 ILE B CD1 1 
ATOM   3974 N N   . LEU B 1 326 ? 142.445 159.344 147.570 1.00 55.07  ? 326 LEU B N   1 
ATOM   3975 C CA  . LEU B 1 326 ? 142.112 160.480 148.427 1.00 57.00  ? 326 LEU B CA  1 
ATOM   3976 C C   . LEU B 1 326 ? 141.171 160.069 149.554 1.00 60.59  ? 326 LEU B C   1 
ATOM   3977 O O   . LEU B 1 326 ? 141.350 160.476 150.710 1.00 59.04  ? 326 LEU B O   1 
ATOM   3978 C CB  . LEU B 1 326 ? 141.490 161.600 147.600 1.00 54.24  ? 326 LEU B CB  1 
ATOM   3979 C CG  . LEU B 1 326 ? 142.472 162.379 146.736 1.00 58.90  ? 326 LEU B CG  1 
ATOM   3980 C CD1 . LEU B 1 326 ? 141.753 163.497 146.027 1.00 63.99  ? 326 LEU B CD1 1 
ATOM   3981 C CD2 . LEU B 1 326 ? 143.598 162.923 147.590 1.00 61.97  ? 326 LEU B CD2 1 
ATOM   3982 N N   . TRP B 1 327 ? 140.161 159.262 149.232 1.00 59.23  ? 327 TRP B N   1 
ATOM   3983 C CA  . TRP B 1 327 ? 139.198 158.812 150.230 1.00 55.75  ? 327 TRP B CA  1 
ATOM   3984 C C   . TRP B 1 327 ? 139.868 157.968 151.304 1.00 57.41  ? 327 TRP B C   1 
ATOM   3985 O O   . TRP B 1 327 ? 139.606 158.145 152.499 1.00 61.43  ? 327 TRP B O   1 
ATOM   3986 C CB  . TRP B 1 327 ? 138.089 158.031 149.530 1.00 54.80  ? 327 TRP B CB  1 
ATOM   3987 C CG  . TRP B 1 327 ? 136.984 157.555 150.400 1.00 52.80  ? 327 TRP B CG  1 
ATOM   3988 C CD1 . TRP B 1 327 ? 135.901 158.270 150.813 1.00 54.40  ? 327 TRP B CD1 1 
ATOM   3989 C CD2 . TRP B 1 327 ? 136.827 156.241 150.938 1.00 54.28  ? 327 TRP B CD2 1 
ATOM   3990 N NE1 . TRP B 1 327 ? 135.089 157.488 151.591 1.00 59.29  ? 327 TRP B NE1 1 
ATOM   3991 C CE2 . TRP B 1 327 ? 135.637 156.236 151.683 1.00 61.04  ? 327 TRP B CE2 1 
ATOM   3992 C CE3 . TRP B 1 327 ? 137.583 155.070 150.870 1.00 52.21  ? 327 TRP B CE3 1 
ATOM   3993 C CZ2 . TRP B 1 327 ? 135.185 155.106 152.356 1.00 61.85  ? 327 TRP B CZ2 1 
ATOM   3994 C CZ3 . TRP B 1 327 ? 137.133 153.952 151.538 1.00 53.34  ? 327 TRP B CZ3 1 
ATOM   3995 C CH2 . TRP B 1 327 ? 135.947 153.976 152.270 1.00 59.07  ? 327 TRP B CH2 1 
ATOM   3996 N N   . CYS B 1 328 ? 140.746 157.050 150.897 1.00 55.79  ? 328 CYS B N   1 
ATOM   3997 C CA  . CYS B 1 328 ? 141.455 156.215 151.857 1.00 56.54  ? 328 CYS B CA  1 
ATOM   3998 C C   . CYS B 1 328 ? 142.389 157.044 152.725 1.00 61.16  ? 328 CYS B C   1 
ATOM   3999 O O   . CYS B 1 328 ? 142.499 156.802 153.930 1.00 66.23  ? 328 CYS B O   1 
ATOM   4000 C CB  . CYS B 1 328 ? 142.231 155.120 151.130 1.00 53.03  ? 328 CYS B CB  1 
ATOM   4001 S SG  . CYS B 1 328 ? 141.201 153.816 150.434 1.00 65.21  ? 328 CYS B SG  1 
ATOM   4002 N N   . LEU B 1 329 ? 143.070 158.027 152.133 1.00 56.44  ? 329 LEU B N   1 
ATOM   4003 C CA  . LEU B 1 329 ? 143.946 158.889 152.919 1.00 57.45  ? 329 LEU B CA  1 
ATOM   4004 C C   . LEU B 1 329 ? 143.154 159.677 153.954 1.00 63.01  ? 329 LEU B C   1 
ATOM   4005 O O   . LEU B 1 329 ? 143.557 159.773 155.117 1.00 66.30  ? 329 LEU B O   1 
ATOM   4006 C CB  . LEU B 1 329 ? 144.718 159.830 151.998 1.00 53.28  ? 329 LEU B CB  1 
ATOM   4007 C CG  . LEU B 1 329 ? 145.821 159.186 151.161 1.00 48.13  ? 329 LEU B CG  1 
ATOM   4008 C CD1 . LEU B 1 329 ? 146.591 160.240 150.390 1.00 50.48  ? 329 LEU B CD1 1 
ATOM   4009 C CD2 . LEU B 1 329 ? 146.748 158.376 152.042 1.00 44.17  ? 329 LEU B CD2 1 
ATOM   4010 N N   . SER B 1 330 ? 142.012 160.239 153.552 1.00 61.88  ? 330 SER B N   1 
ATOM   4011 C CA  . SER B 1 330 ? 141.185 160.984 154.497 1.00 67.29  ? 330 SER B CA  1 
ATOM   4012 C C   . SER B 1 330 ? 140.670 160.088 155.616 1.00 70.36  ? 330 SER B C   1 
ATOM   4013 O O   . SER B 1 330 ? 140.720 160.456 156.798 1.00 74.78  ? 330 SER B O   1 
ATOM   4014 C CB  . SER B 1 330 ? 140.016 161.633 153.761 1.00 68.18  ? 330 SER B CB  1 
ATOM   4015 O OG  . SER B 1 330 ? 138.985 161.982 154.667 1.00 72.56  ? 330 SER B OG  1 
ATOM   4016 N N   . LEU B 1 331 ? 140.169 158.905 155.260 1.00 66.48  ? 331 LEU B N   1 
ATOM   4017 C CA  . LEU B 1 331 ? 139.619 158.002 156.261 1.00 64.74  ? 331 LEU B CA  1 
ATOM   4018 C C   . LEU B 1 331 ? 140.700 157.530 157.224 1.00 73.83  ? 331 LEU B C   1 
ATOM   4019 O O   . LEU B 1 331 ? 140.482 157.473 158.440 1.00 81.06  ? 331 LEU B O   1 
ATOM   4020 C CB  . LEU B 1 331 ? 138.945 156.824 155.563 1.00 61.16  ? 331 LEU B CB  1 
ATOM   4021 C CG  . LEU B 1 331 ? 138.116 155.853 156.395 1.00 65.04  ? 331 LEU B CG  1 
ATOM   4022 C CD1 . LEU B 1 331 ? 137.233 156.607 157.355 1.00 70.49  ? 331 LEU B CD1 1 
ATOM   4023 C CD2 . LEU B 1 331 ? 137.278 154.990 155.473 1.00 63.91  ? 331 LEU B CD2 1 
ATOM   4024 N N   . LEU B 1 332 ? 141.885 157.214 156.701 1.00 73.62  ? 332 LEU B N   1 
ATOM   4025 C CA  . LEU B 1 332 ? 142.987 156.786 157.550 1.00 77.42  ? 332 LEU B CA  1 
ATOM   4026 C C   . LEU B 1 332 ? 143.487 157.920 158.430 1.00 79.01  ? 332 LEU B C   1 
ATOM   4027 O O   . LEU B 1 332 ? 143.897 157.681 159.570 1.00 82.93  ? 332 LEU B O   1 
ATOM   4028 C CB  . LEU B 1 332 ? 144.119 156.238 156.684 1.00 74.29  ? 332 LEU B CB  1 
ATOM   4029 C CG  . LEU B 1 332 ? 145.267 155.531 157.391 1.00 75.21  ? 332 LEU B CG  1 
ATOM   4030 C CD1 . LEU B 1 332 ? 144.729 154.440 158.292 1.00 73.98  ? 332 LEU B CD1 1 
ATOM   4031 C CD2 . LEU B 1 332 ? 146.212 154.955 156.358 1.00 72.40  ? 332 LEU B CD2 1 
ATOM   4032 N N   . ALA B 1 333 ? 143.472 159.153 157.921 1.00 74.62  ? 333 ALA B N   1 
ATOM   4033 C CA  . ALA B 1 333 ? 143.845 160.294 158.744 1.00 78.58  ? 333 ALA B CA  1 
ATOM   4034 C C   . ALA B 1 333 ? 142.879 160.456 159.905 1.00 87.16  ? 333 ALA B C   1 
ATOM   4035 O O   . ALA B 1 333 ? 143.293 160.652 161.052 1.00 94.27  ? 333 ALA B O   1 
ATOM   4036 C CB  . ALA B 1 333 ? 143.886 161.563 157.895 1.00 76.37  ? 333 ALA B CB  1 
ATOM   4037 N N   . CYS B 1 334 ? 141.578 160.353 159.631 1.00 84.96  ? 334 CYS B N   1 
ATOM   4038 C CA  . CYS B 1 334 ? 140.611 160.452 160.718 1.00 85.77  ? 334 CYS B CA  1 
ATOM   4039 C C   . CYS B 1 334 ? 140.758 159.299 161.701 1.00 88.47  ? 334 CYS B C   1 
ATOM   4040 O O   . CYS B 1 334 ? 140.532 159.477 162.902 1.00 91.24  ? 334 CYS B O   1 
ATOM   4041 C CB  . CYS B 1 334 ? 139.189 160.500 160.168 1.00 82.47  ? 334 CYS B CB  1 
ATOM   4042 S SG  . CYS B 1 334 ? 137.951 160.813 161.440 1.00 97.45  ? 334 CYS B SG  1 
ATOM   4043 N N   . PHE B 1 335 ? 141.130 158.115 161.214 1.00 88.81  ? 335 PHE B N   1 
ATOM   4044 C CA  . PHE B 1 335 ? 141.302 156.968 162.100 1.00 92.73  ? 335 PHE B CA  1 
ATOM   4045 C C   . PHE B 1 335 ? 142.514 157.135 163.009 1.00 99.27  ? 335 PHE B C   1 
ATOM   4046 O O   . PHE B 1 335 ? 142.427 156.921 164.223 1.00 102.11 ? 335 PHE B O   1 
ATOM   4047 C CB  . PHE B 1 335 ? 141.439 155.692 161.274 1.00 88.92  ? 335 PHE B CB  1 
ATOM   4048 C CG  . PHE B 1 335 ? 140.152 154.973 161.055 1.00 87.66  ? 335 PHE B CG  1 
ATOM   4049 C CD1 . PHE B 1 335 ? 139.050 155.636 160.555 1.00 83.64  ? 335 PHE B CD1 1 
ATOM   4050 C CD2 . PHE B 1 335 ? 140.046 153.626 161.339 1.00 90.60  ? 335 PHE B CD2 1 
ATOM   4051 C CE1 . PHE B 1 335 ? 137.865 154.969 160.352 1.00 87.20  ? 335 PHE B CE1 1 
ATOM   4052 C CE2 . PHE B 1 335 ? 138.865 152.954 161.132 1.00 91.93  ? 335 PHE B CE2 1 
ATOM   4053 C CZ  . PHE B 1 335 ? 137.772 153.627 160.640 1.00 92.44  ? 335 PHE B CZ  1 
ATOM   4054 N N   . PHE B 1 336 ? 143.651 157.527 162.442 1.00 97.52  ? 336 PHE B N   1 
ATOM   4055 C CA  . PHE B 1 336 ? 144.932 157.437 163.127 1.00 98.93  ? 336 PHE B CA  1 
ATOM   4056 C C   . PHE B 1 336 ? 145.217 158.616 164.042 1.00 106.83 ? 336 PHE B C   1 
ATOM   4057 O O   . PHE B 1 336 ? 146.298 158.660 164.638 1.00 113.22 ? 336 PHE B O   1 
ATOM   4058 C CB  . PHE B 1 336 ? 146.067 157.296 162.110 1.00 94.24  ? 336 PHE B CB  1 
ATOM   4059 C CG  . PHE B 1 336 ? 146.532 155.885 161.918 1.00 89.27  ? 336 PHE B CG  1 
ATOM   4060 C CD1 . PHE B 1 336 ? 146.382 154.954 162.928 1.00 94.93  ? 336 PHE B CD1 1 
ATOM   4061 C CD2 . PHE B 1 336 ? 147.116 155.489 160.732 1.00 86.47  ? 336 PHE B CD2 1 
ATOM   4062 C CE1 . PHE B 1 336 ? 146.808 153.655 162.756 1.00 99.38  ? 336 PHE B CE1 1 
ATOM   4063 C CE2 . PHE B 1 336 ? 147.543 154.188 160.553 1.00 87.55  ? 336 PHE B CE2 1 
ATOM   4064 C CZ  . PHE B 1 336 ? 147.388 153.270 161.568 1.00 94.88  ? 336 PHE B CZ  1 
ATOM   4065 N N   . ALA B 1 337 ? 144.285 159.561 164.170 1.00 107.10 ? 337 ALA B N   1 
ATOM   4066 C CA  . ALA B 1 337 ? 144.419 160.678 165.098 1.00 115.11 ? 337 ALA B CA  1 
ATOM   4067 C C   . ALA B 1 337 ? 145.739 161.408 164.884 1.00 117.63 ? 337 ALA B C   1 
ATOM   4068 O O   . ALA B 1 337 ? 146.663 161.276 165.698 1.00 120.54 ? 337 ALA B O   1 
ATOM   4069 C CB  . ALA B 1 337 ? 144.306 160.197 166.547 1.00 114.70 ? 337 ALA B CB  1 
ATOM   4070 N N   . PRO B 1 338 ? 145.869 162.177 163.810 1.00 116.25 ? 338 PRO B N   1 
ATOM   4071 C CA  . PRO B 1 338 ? 147.132 162.874 163.547 1.00 120.83 ? 338 PRO B CA  1 
ATOM   4072 C C   . PRO B 1 338 ? 147.359 164.013 164.529 1.00 126.17 ? 338 PRO B C   1 
ATOM   4073 O O   . PRO B 1 338 ? 146.627 164.133 165.517 1.00 125.22 ? 338 PRO B O   1 
ATOM   4074 C CB  . PRO B 1 338 ? 146.950 163.384 162.115 1.00 117.64 ? 338 PRO B CB  1 
ATOM   4075 C CG  . PRO B 1 338 ? 145.486 163.627 162.017 1.00 113.90 ? 338 PRO B CG  1 
ATOM   4076 C CD  . PRO B 1 338 ? 144.822 162.559 162.850 1.00 111.69 ? 338 PRO B CD  1 
ATOM   4077 N N   . ILE B 1 339 ? 148.381 164.832 164.268 1.00 129.37 ? 339 ILE B N   1 
ATOM   4078 C CA  . ILE B 1 339 ? 148.843 165.889 165.166 1.00 133.36 ? 339 ILE B CA  1 
ATOM   4079 C C   . ILE B 1 339 ? 147.668 166.626 165.795 1.00 134.27 ? 339 ILE B C   1 
ATOM   4080 O O   . ILE B 1 339 ? 146.740 167.054 165.100 1.00 132.18 ? 339 ILE B O   1 
ATOM   4081 C CB  . ILE B 1 339 ? 149.770 166.869 164.419 1.00 132.88 ? 339 ILE B CB  1 
ATOM   4082 C CG1 . ILE B 1 339 ? 150.144 168.051 165.316 1.00 133.89 ? 339 ILE B CG1 1 
ATOM   4083 C CG2 . ILE B 1 339 ? 149.123 167.342 163.122 1.00 126.61 ? 339 ILE B CG2 1 
ATOM   4084 C CD1 . ILE B 1 339 ? 151.095 169.036 164.667 1.00 130.67 ? 339 ILE B CD1 1 
ATOM   4085 N N   . SER B 1 340 ? 147.695 166.764 167.121 1.00 135.87 ? 340 SER B N   1 
ATOM   4086 C CA  . SER B 1 340 ? 146.562 167.309 167.856 1.00 135.90 ? 340 SER B CA  1 
ATOM   4087 C C   . SER B 1 340 ? 146.506 168.826 167.743 1.00 135.69 ? 340 SER B C   1 
ATOM   4088 O O   . SER B 1 340 ? 146.454 169.532 168.755 1.00 136.32 ? 340 SER B O   1 
ATOM   4089 C CB  . SER B 1 340 ? 146.632 166.889 169.326 1.00 138.11 ? 340 SER B CB  1 
ATOM   4090 O OG  . SER B 1 340 ? 147.862 167.280 169.908 1.00 138.21 ? 340 SER B OG  1 
ATOM   4091 N N   . VAL B 1 341 ? 146.517 169.332 166.511 1.00 133.31 ? 341 VAL B N   1 
ATOM   4092 C CA  . VAL B 1 341 ? 146.336 170.749 166.225 1.00 132.45 ? 341 VAL B CA  1 
ATOM   4093 C C   . VAL B 1 341 ? 145.189 170.968 165.248 1.00 129.02 ? 341 VAL B C   1 
ATOM   4094 O O   . VAL B 1 341 ? 144.263 171.739 165.520 1.00 127.56 ? 341 VAL B O   1 
ATOM   4095 C CB  . VAL B 1 341 ? 147.638 171.387 165.690 1.00 132.93 ? 341 VAL B CB  1 
ATOM   4096 C CG1 . VAL B 1 341 ? 147.423 172.864 165.402 1.00 131.09 ? 341 VAL B CG1 1 
ATOM   4097 C CG2 . VAL B 1 341 ? 148.774 171.193 166.680 1.00 129.70 ? 341 VAL B CG2 1 
ATOM   4098 N N   . ILE B 1 342 ? 145.230 170.291 164.107 1.00 127.00 ? 342 ILE B N   1 
ATOM   4099 C CA  . ILE B 1 342 ? 144.157 170.351 163.118 1.00 124.33 ? 342 ILE B CA  1 
ATOM   4100 C C   . ILE B 1 342 ? 143.165 169.248 163.445 1.00 124.01 ? 342 ILE B C   1 
ATOM   4101 O O   . ILE B 1 342 ? 143.522 168.061 163.363 1.00 125.45 ? 342 ILE B O   1 
ATOM   4102 C CB  . ILE B 1 342 ? 144.702 170.199 161.693 1.00 121.05 ? 342 ILE B CB  1 
ATOM   4103 C CG1 . ILE B 1 342 ? 145.709 171.308 161.389 1.00 121.30 ? 342 ILE B CG1 1 
ATOM   4104 C CG2 . ILE B 1 342 ? 143.568 170.227 160.688 1.00 117.46 ? 342 ILE B CG2 1 
ATOM   4105 C CD1 . ILE B 1 342 ? 145.131 172.699 161.512 1.00 121.31 ? 342 ILE B CD1 1 
ATOM   4106 N N   . PRO B 1 343 ? 141.926 169.572 163.813 1.00 121.40 ? 343 PRO B N   1 
ATOM   4107 C CA  . PRO B 1 343 ? 140.977 168.536 164.221 1.00 114.83 ? 343 PRO B CA  1 
ATOM   4108 C C   . PRO B 1 343 ? 140.591 167.638 163.057 1.00 113.73 ? 343 PRO B C   1 
ATOM   4109 O O   . PRO B 1 343 ? 140.696 168.003 161.885 1.00 112.00 ? 343 PRO B O   1 
ATOM   4110 C CB  . PRO B 1 343 ? 139.777 169.333 164.737 1.00 112.22 ? 343 PRO B CB  1 
ATOM   4111 C CG  . PRO B 1 343 ? 139.879 170.649 164.044 1.00 116.08 ? 343 PRO B CG  1 
ATOM   4112 C CD  . PRO B 1 343 ? 141.344 170.923 163.899 1.00 120.25 ? 343 PRO B CD  1 
ATOM   4113 N N   . THR B 1 344 ? 140.136 166.434 163.410 1.00 111.77 ? 344 THR B N   1 
ATOM   4114 C CA  . THR B 1 344 ? 139.909 165.394 162.412 1.00 108.93 ? 344 THR B CA  1 
ATOM   4115 C C   . THR B 1 344 ? 138.765 165.736 161.464 1.00 104.32 ? 344 THR B C   1 
ATOM   4116 O O   . THR B 1 344 ? 138.822 165.385 160.280 1.00 97.26  ? 344 THR B O   1 
ATOM   4117 C CB  . THR B 1 344 ? 139.631 164.062 163.105 1.00 106.83 ? 344 THR B CB  1 
ATOM   4118 O OG1 . THR B 1 344 ? 138.474 164.190 163.938 1.00 111.09 ? 344 THR B OG1 1 
ATOM   4119 C CG2 . THR B 1 344 ? 140.818 163.656 163.962 1.00 104.73 ? 344 THR B CG2 1 
ATOM   4120 N N   . TYR B 1 345 ? 137.734 166.429 161.951 1.00 107.80 ? 345 TYR B N   1 
ATOM   4121 C CA  . TYR B 1 345 ? 136.526 166.618 161.156 1.00 107.32 ? 345 TYR B CA  1 
ATOM   4122 C C   . TYR B 1 345 ? 136.756 167.454 159.906 1.00 104.14 ? 345 TYR B C   1 
ATOM   4123 O O   . TYR B 1 345 ? 135.873 167.497 159.044 1.00 101.62 ? 345 TYR B O   1 
ATOM   4124 C CB  . TYR B 1 345 ? 135.421 167.253 162.004 1.00 106.20 ? 345 TYR B CB  1 
ATOM   4125 C CG  . TYR B 1 345 ? 135.758 168.611 162.573 1.00 109.91 ? 345 TYR B CG  1 
ATOM   4126 C CD1 . TYR B 1 345 ? 135.657 169.758 161.797 1.00 112.05 ? 345 TYR B CD1 1 
ATOM   4127 C CD2 . TYR B 1 345 ? 136.153 168.749 163.893 1.00 114.51 ? 345 TYR B CD2 1 
ATOM   4128 C CE1 . TYR B 1 345 ? 135.958 171.000 162.315 1.00 116.49 ? 345 TYR B CE1 1 
ATOM   4129 C CE2 . TYR B 1 345 ? 136.451 169.987 164.421 1.00 120.47 ? 345 TYR B CE2 1 
ATOM   4130 C CZ  . TYR B 1 345 ? 136.354 171.108 163.627 1.00 122.39 ? 345 TYR B CZ  1 
ATOM   4131 O OH  . TYR B 1 345 ? 136.651 172.345 164.147 1.00 129.18 ? 345 TYR B OH  1 
ATOM   4132 N N   . VAL B 1 346 ? 137.897 168.132 159.790 1.00 101.83 ? 346 VAL B N   1 
ATOM   4133 C CA  . VAL B 1 346 ? 138.175 168.868 158.565 1.00 99.64  ? 346 VAL B CA  1 
ATOM   4134 C C   . VAL B 1 346 ? 138.497 167.932 157.406 1.00 96.33  ? 346 VAL B C   1 
ATOM   4135 O O   . VAL B 1 346 ? 138.329 168.319 156.242 1.00 91.93  ? 346 VAL B O   1 
ATOM   4136 C CB  . VAL B 1 346 ? 139.317 169.873 158.790 1.00 97.54  ? 346 VAL B CB  1 
ATOM   4137 C CG1 . VAL B 1 346 ? 140.643 169.156 158.898 1.00 93.62  ? 346 VAL B CG1 1 
ATOM   4138 C CG2 . VAL B 1 346 ? 139.350 170.907 157.678 1.00 97.64  ? 346 VAL B CG2 1 
ATOM   4139 N N   . TYR B 1 347 ? 138.942 166.706 157.688 1.00 94.55  ? 347 TYR B N   1 
ATOM   4140 C CA  . TYR B 1 347 ? 139.319 165.795 156.608 1.00 89.21  ? 347 TYR B CA  1 
ATOM   4141 C C   . TYR B 1 347 ? 138.154 165.431 155.696 1.00 91.00  ? 347 TYR B C   1 
ATOM   4142 O O   . TYR B 1 347 ? 138.319 165.519 154.466 1.00 87.92  ? 347 TYR B O   1 
ATOM   4143 C CB  . TYR B 1 347 ? 139.994 164.553 157.196 1.00 83.80  ? 347 TYR B CB  1 
ATOM   4144 C CG  . TYR B 1 347 ? 141.373 164.834 157.734 1.00 93.11  ? 347 TYR B CG  1 
ATOM   4145 C CD1 . TYR B 1 347 ? 142.410 165.182 156.881 1.00 94.31  ? 347 TYR B CD1 1 
ATOM   4146 C CD2 . TYR B 1 347 ? 141.641 164.756 159.092 1.00 96.50  ? 347 TYR B CD2 1 
ATOM   4147 C CE1 . TYR B 1 347 ? 143.674 165.444 157.366 1.00 91.61  ? 347 TYR B CE1 1 
ATOM   4148 C CE2 . TYR B 1 347 ? 142.902 165.013 159.586 1.00 95.64  ? 347 TYR B CE2 1 
ATOM   4149 C CZ  . TYR B 1 347 ? 143.914 165.357 158.718 1.00 93.92  ? 347 TYR B CZ  1 
ATOM   4150 O OH  . TYR B 1 347 ? 145.172 165.616 159.206 1.00 101.32 ? 347 TYR B OH  1 
ATOM   4151 N N   . PRO B 1 348 ? 136.981 165.015 156.192 1.00 93.04  ? 348 PRO B N   1 
ATOM   4152 C CA  . PRO B 1 348 ? 135.865 164.788 155.263 1.00 84.14  ? 348 PRO B CA  1 
ATOM   4153 C C   . PRO B 1 348 ? 135.452 166.038 154.517 1.00 87.42  ? 348 PRO B C   1 
ATOM   4154 O O   . PRO B 1 348 ? 135.016 165.944 153.365 1.00 88.38  ? 348 PRO B O   1 
ATOM   4155 C CB  . PRO B 1 348 ? 134.745 164.269 156.174 1.00 81.50  ? 348 PRO B CB  1 
ATOM   4156 C CG  . PRO B 1 348 ? 135.100 164.735 157.521 1.00 90.14  ? 348 PRO B CG  1 
ATOM   4157 C CD  . PRO B 1 348 ? 136.591 164.706 157.579 1.00 96.28  ? 348 PRO B CD  1 
ATOM   4158 N N   . LEU B 1 349 ? 135.579 167.214 155.135 1.00 91.81  ? 349 LEU B N   1 
ATOM   4159 C CA  . LEU B 1 349 ? 135.261 168.452 154.433 1.00 93.88  ? 349 LEU B CA  1 
ATOM   4160 C C   . LEU B 1 349 ? 136.187 168.663 153.243 1.00 90.17  ? 349 LEU B C   1 
ATOM   4161 O O   . LEU B 1 349 ? 135.742 169.080 152.168 1.00 84.83  ? 349 LEU B O   1 
ATOM   4162 C CB  . LEU B 1 349 ? 135.339 169.639 155.392 1.00 92.14  ? 349 LEU B CB  1 
ATOM   4163 C CG  . LEU B 1 349 ? 134.198 169.754 156.402 1.00 95.33  ? 349 LEU B CG  1 
ATOM   4164 C CD1 . LEU B 1 349 ? 134.403 170.953 157.309 1.00 97.84  ? 349 LEU B CD1 1 
ATOM   4165 C CD2 . LEU B 1 349 ? 132.865 169.846 155.681 1.00 93.19  ? 349 LEU B CD2 1 
ATOM   4166 N N   . ALA B 1 350 ? 137.478 168.381 153.415 1.00 87.54  ? 350 ALA B N   1 
ATOM   4167 C CA  . ALA B 1 350 ? 138.421 168.553 152.315 1.00 89.62  ? 350 ALA B CA  1 
ATOM   4168 C C   . ALA B 1 350 ? 138.136 167.571 151.185 1.00 90.42  ? 350 ALA B C   1 
ATOM   4169 O O   . ALA B 1 350 ? 137.997 167.973 150.022 1.00 84.90  ? 350 ALA B O   1 
ATOM   4170 C CB  . ALA B 1 350 ? 139.852 168.389 152.823 1.00 89.28  ? 350 ALA B CB  1 
ATOM   4171 N N   . LEU B 1 351 ? 138.016 166.281 151.517 1.00 93.20  ? 351 LEU B N   1 
ATOM   4172 C CA  . LEU B 1 351 ? 137.872 165.235 150.507 1.00 88.16  ? 351 LEU B CA  1 
ATOM   4173 C C   . LEU B 1 351 ? 136.735 165.546 149.546 1.00 83.99  ? 351 LEU B C   1 
ATOM   4174 O O   . LEU B 1 351 ? 136.957 165.779 148.352 1.00 83.32  ? 351 LEU B O   1 
ATOM   4175 C CB  . LEU B 1 351 ? 137.643 163.885 151.190 1.00 79.45  ? 351 LEU B CB  1 
ATOM   4176 C CG  . LEU B 1 351 ? 137.055 162.772 150.321 1.00 68.17  ? 351 LEU B CG  1 
ATOM   4177 C CD1 . LEU B 1 351 ? 138.011 162.393 149.211 1.00 72.34  ? 351 LEU B CD1 1 
ATOM   4178 C CD2 . LEU B 1 351 ? 136.704 161.565 151.164 1.00 62.27  ? 351 LEU B CD2 1 
ATOM   4179 N N   . TYR B 1 352 ? 135.507 165.595 150.068 1.00 80.05  ? 352 TYR B N   1 
ATOM   4180 C CA  . TYR B 1 352 ? 134.368 165.942 149.231 1.00 80.46  ? 352 TYR B CA  1 
ATOM   4181 C C   . TYR B 1 352 ? 134.600 167.278 148.548 1.00 83.20  ? 352 TYR B C   1 
ATOM   4182 O O   . TYR B 1 352 ? 134.328 167.428 147.349 1.00 84.73  ? 352 TYR B O   1 
ATOM   4183 C CB  . TYR B 1 352 ? 133.089 165.968 150.065 1.00 78.33  ? 352 TYR B CB  1 
ATOM   4184 C CG  . TYR B 1 352 ? 132.718 164.616 150.619 1.00 78.58  ? 352 TYR B CG  1 
ATOM   4185 C CD1 . TYR B 1 352 ? 132.207 163.629 149.795 1.00 74.20  ? 352 TYR B CD1 1 
ATOM   4186 C CD2 . TYR B 1 352 ? 132.883 164.324 151.964 1.00 83.50  ? 352 TYR B CD2 1 
ATOM   4187 C CE1 . TYR B 1 352 ? 131.873 162.393 150.290 1.00 73.09  ? 352 TYR B CE1 1 
ATOM   4188 C CE2 . TYR B 1 352 ? 132.552 163.090 152.470 1.00 81.71  ? 352 TYR B CE2 1 
ATOM   4189 C CZ  . TYR B 1 352 ? 132.046 162.130 151.629 1.00 77.84  ? 352 TYR B CZ  1 
ATOM   4190 O OH  . TYR B 1 352 ? 131.713 160.897 152.128 1.00 77.93  ? 352 TYR B OH  1 
ATOM   4191 N N   . GLY B 1 353 ? 135.165 168.239 149.282 1.00 78.30  ? 353 GLY B N   1 
ATOM   4192 C CA  . GLY B 1 353 ? 135.477 169.519 148.675 1.00 81.07  ? 353 GLY B CA  1 
ATOM   4193 C C   . GLY B 1 353 ? 136.300 169.357 147.418 1.00 82.86  ? 353 GLY B C   1 
ATOM   4194 O O   . GLY B 1 353 ? 135.932 169.858 146.352 1.00 83.10  ? 353 GLY B O   1 
ATOM   4195 N N   . PHE B 1 354 ? 137.383 168.578 147.504 1.00 82.67  ? 354 PHE B N   1 
ATOM   4196 C CA  . PHE B 1 354 ? 138.210 168.363 146.323 1.00 82.10  ? 354 PHE B CA  1 
ATOM   4197 C C   . PHE B 1 354 ? 137.376 167.802 145.185 1.00 79.68  ? 354 PHE B C   1 
ATOM   4198 O O   . PHE B 1 354 ? 137.447 168.290 144.051 1.00 78.10  ? 354 PHE B O   1 
ATOM   4199 C CB  . PHE B 1 354 ? 139.378 167.429 146.634 1.00 80.92  ? 354 PHE B CB  1 
ATOM   4200 C CG  . PHE B 1 354 ? 140.245 167.142 145.438 1.00 80.45  ? 354 PHE B CG  1 
ATOM   4201 C CD1 . PHE B 1 354 ? 139.964 166.078 144.595 1.00 79.66  ? 354 PHE B CD1 1 
ATOM   4202 C CD2 . PHE B 1 354 ? 141.329 167.951 145.142 1.00 81.04  ? 354 PHE B CD2 1 
ATOM   4203 C CE1 . PHE B 1 354 ? 140.752 165.820 143.492 1.00 79.08  ? 354 PHE B CE1 1 
ATOM   4204 C CE2 . PHE B 1 354 ? 142.121 167.696 144.037 1.00 82.99  ? 354 PHE B CE2 1 
ATOM   4205 C CZ  . PHE B 1 354 ? 141.831 166.629 143.213 1.00 81.32  ? 354 PHE B CZ  1 
ATOM   4206 N N   . MET B 1 355 ? 136.548 166.797 145.480 1.00 79.48  ? 355 MET B N   1 
ATOM   4207 C CA  . MET B 1 355 ? 135.724 166.214 144.432 1.00 77.34  ? 355 MET B CA  1 
ATOM   4208 C C   . MET B 1 355 ? 134.839 167.276 143.804 1.00 79.73  ? 355 MET B C   1 
ATOM   4209 O O   . MET B 1 355 ? 134.757 167.375 142.574 1.00 80.38  ? 355 MET B O   1 
ATOM   4210 C CB  . MET B 1 355 ? 134.894 165.058 144.986 1.00 75.82  ? 355 MET B CB  1 
ATOM   4211 C CG  . MET B 1 355 ? 135.735 163.856 145.383 1.00 82.91  ? 355 MET B CG  1 
ATOM   4212 S SD  . MET B 1 355 ? 134.817 162.307 145.456 1.00 96.23  ? 355 MET B SD  1 
ATOM   4213 C CE  . MET B 1 355 ? 133.788 162.588 146.890 1.00 85.59  ? 355 MET B CE  1 
ATOM   4214 N N   . VAL B 1 356 ? 134.229 168.129 144.631 1.00 80.03  ? 356 VAL B N   1 
ATOM   4215 C CA  . VAL B 1 356 ? 133.454 169.238 144.089 1.00 78.45  ? 356 VAL B CA  1 
ATOM   4216 C C   . VAL B 1 356 ? 134.344 170.114 143.220 1.00 79.57  ? 356 VAL B C   1 
ATOM   4217 O O   . VAL B 1 356 ? 134.017 170.411 142.065 1.00 76.44  ? 356 VAL B O   1 
ATOM   4218 C CB  . VAL B 1 356 ? 132.795 170.041 145.222 1.00 75.98  ? 356 VAL B CB  1 
ATOM   4219 C CG1 . VAL B 1 356 ? 132.042 171.226 144.652 1.00 79.40  ? 356 VAL B CG1 1 
ATOM   4220 C CG2 . VAL B 1 356 ? 131.866 169.149 146.021 1.00 75.03  ? 356 VAL B CG2 1 
ATOM   4221 N N   . PHE B 1 357 ? 135.517 170.486 143.743 1.00 80.98  ? 357 PHE B N   1 
ATOM   4222 C CA  . PHE B 1 357 ? 136.468 171.235 142.933 1.00 81.31  ? 357 PHE B CA  1 
ATOM   4223 C C   . PHE B 1 357 ? 136.857 170.446 141.696 1.00 81.78  ? 357 PHE B C   1 
ATOM   4224 O O   . PHE B 1 357 ? 136.966 171.008 140.599 1.00 83.09  ? 357 PHE B O   1 
ATOM   4225 C CB  . PHE B 1 357 ? 137.714 171.587 143.742 1.00 82.15  ? 357 PHE B CB  1 
ATOM   4226 C CG  . PHE B 1 357 ? 138.941 171.775 142.896 1.00 85.14  ? 357 PHE B CG  1 
ATOM   4227 C CD1 . PHE B 1 357 ? 139.095 172.909 142.115 1.00 87.04  ? 357 PHE B CD1 1 
ATOM   4228 C CD2 . PHE B 1 357 ? 139.935 170.812 142.870 1.00 84.61  ? 357 PHE B CD2 1 
ATOM   4229 C CE1 . PHE B 1 357 ? 140.219 173.079 141.330 1.00 88.50  ? 357 PHE B CE1 1 
ATOM   4230 C CE2 . PHE B 1 357 ? 141.061 170.977 142.087 1.00 90.17  ? 357 PHE B CE2 1 
ATOM   4231 C CZ  . PHE B 1 357 ? 141.204 172.111 141.316 1.00 91.03  ? 357 PHE B CZ  1 
ATOM   4232 N N   . PHE B 1 358 ? 137.041 169.132 141.848 1.00 80.86  ? 358 PHE B N   1 
ATOM   4233 C CA  . PHE B 1 358 ? 137.447 168.317 140.713 1.00 77.08  ? 358 PHE B CA  1 
ATOM   4234 C C   . PHE B 1 358 ? 136.425 168.395 139.594 1.00 72.77  ? 358 PHE B C   1 
ATOM   4235 O O   . PHE B 1 358 ? 136.755 168.133 138.435 1.00 69.02  ? 358 PHE B O   1 
ATOM   4236 C CB  . PHE B 1 358 ? 137.653 166.870 141.157 1.00 78.95  ? 358 PHE B CB  1 
ATOM   4237 C CG  . PHE B 1 358 ? 138.382 166.030 140.157 1.00 75.95  ? 358 PHE B CG  1 
ATOM   4238 C CD1 . PHE B 1 358 ? 137.688 165.289 139.220 1.00 77.99  ? 358 PHE B CD1 1 
ATOM   4239 C CD2 . PHE B 1 358 ? 139.761 165.978 140.156 1.00 74.61  ? 358 PHE B CD2 1 
ATOM   4240 C CE1 . PHE B 1 358 ? 138.356 164.517 138.299 1.00 77.25  ? 358 PHE B CE1 1 
ATOM   4241 C CE2 . PHE B 1 358 ? 140.434 165.206 139.239 1.00 81.45  ? 358 PHE B CE2 1 
ATOM   4242 C CZ  . PHE B 1 358 ? 139.730 164.474 138.309 1.00 82.16  ? 358 PHE B CZ  1 
ATOM   4243 N N   . LEU B 1 359 ? 135.188 168.768 139.915 1.00 74.58  ? 359 LEU B N   1 
ATOM   4244 C CA  . LEU B 1 359 ? 134.184 168.973 138.885 1.00 73.79  ? 359 LEU B CA  1 
ATOM   4245 C C   . LEU B 1 359 ? 134.078 170.426 138.446 1.00 78.93  ? 359 LEU B C   1 
ATOM   4246 O O   . LEU B 1 359 ? 133.777 170.688 137.276 1.00 78.55  ? 359 LEU B O   1 
ATOM   4247 C CB  . LEU B 1 359 ? 132.818 168.492 139.376 1.00 67.97  ? 359 LEU B CB  1 
ATOM   4248 C CG  . LEU B 1 359 ? 132.340 167.135 138.869 1.00 61.44  ? 359 LEU B CG  1 
ATOM   4249 C CD1 . LEU B 1 359 ? 130.931 166.874 139.352 1.00 67.05  ? 359 LEU B CD1 1 
ATOM   4250 C CD2 . LEU B 1 359 ? 132.403 167.081 137.357 1.00 62.34  ? 359 LEU B CD2 1 
ATOM   4251 N N   . ILE B 1 360 ? 134.336 171.377 139.343 1.00 79.35  ? 360 ILE B N   1 
ATOM   4252 C CA  . ILE B 1 360 ? 134.079 172.783 139.056 1.00 76.26  ? 360 ILE B CA  1 
ATOM   4253 C C   . ILE B 1 360 ? 135.361 173.558 138.774 1.00 82.29  ? 360 ILE B C   1 
ATOM   4254 O O   . ILE B 1 360 ? 135.359 174.790 138.839 1.00 89.44  ? 360 ILE B O   1 
ATOM   4255 C CB  . ILE B 1 360 ? 133.279 173.442 140.190 1.00 80.51  ? 360 ILE B CB  1 
ATOM   4256 C CG1 . ILE B 1 360 ? 134.124 173.549 141.459 1.00 86.04  ? 360 ILE B CG1 1 
ATOM   4257 C CG2 . ILE B 1 360 ? 132.016 172.655 140.472 1.00 76.29  ? 360 ILE B CG2 1 
ATOM   4258 C CD1 . ILE B 1 360 ? 133.399 174.197 142.617 1.00 84.80  ? 360 ILE B CD1 1 
ATOM   4259 N N   . ASN B 1 361 ? 136.451 172.872 138.462 1.00 83.08  ? 361 ASN B N   1 
ATOM   4260 C CA  . ASN B 1 361 ? 137.666 173.562 138.056 1.00 82.52  ? 361 ASN B CA  1 
ATOM   4261 C C   . ASN B 1 361 ? 137.458 174.165 136.673 1.00 85.35  ? 361 ASN B C   1 
ATOM   4262 O O   . ASN B 1 361 ? 137.164 173.424 135.723 1.00 85.12  ? 361 ASN B O   1 
ATOM   4263 C CB  . ASN B 1 361 ? 138.853 172.605 138.042 1.00 79.91  ? 361 ASN B CB  1 
ATOM   4264 C CG  . ASN B 1 361 ? 140.105 173.233 137.453 1.00 83.76  ? 361 ASN B CG  1 
ATOM   4265 O OD1 . ASN B 1 361 ? 140.290 174.449 137.501 1.00 83.48  ? 361 ASN B OD1 1 
ATOM   4266 N ND2 . ASN B 1 361 ? 140.974 172.400 136.894 1.00 85.40  ? 361 ASN B ND2 1 
ATOM   4267 N N   . PRO B 1 362 ? 137.588 175.485 136.510 1.00 83.61  ? 362 PRO B N   1 
ATOM   4268 C CA  . PRO B 1 362 ? 137.378 176.081 135.184 1.00 80.53  ? 362 PRO B CA  1 
ATOM   4269 C C   . PRO B 1 362 ? 138.528 175.859 134.222 1.00 77.02  ? 362 PRO B C   1 
ATOM   4270 O O   . PRO B 1 362 ? 138.333 176.012 133.009 1.00 74.92  ? 362 PRO B O   1 
ATOM   4271 C CB  . PRO B 1 362 ? 137.203 177.575 135.492 1.00 81.74  ? 362 PRO B CB  1 
ATOM   4272 C CG  . PRO B 1 362 ? 136.960 177.648 136.973 1.00 80.21  ? 362 PRO B CG  1 
ATOM   4273 C CD  . PRO B 1 362 ? 137.724 176.511 137.552 1.00 80.31  ? 362 PRO B CD  1 
ATOM   4274 N N   . THR B 1 363 ? 139.711 175.509 134.717 1.00 78.23  ? 363 THR B N   1 
ATOM   4275 C CA  . THR B 1 363 ? 140.869 175.343 133.852 1.00 82.64  ? 363 THR B CA  1 
ATOM   4276 C C   . THR B 1 363 ? 140.685 174.142 132.935 1.00 80.86  ? 363 THR B C   1 
ATOM   4277 O O   . THR B 1 363 ? 140.198 173.089 133.353 1.00 83.70  ? 363 THR B O   1 
ATOM   4278 C CB  . THR B 1 363 ? 142.134 175.169 134.691 1.00 89.26  ? 363 THR B CB  1 
ATOM   4279 O OG1 . THR B 1 363 ? 142.103 176.076 135.800 1.00 88.56  ? 363 THR B OG1 1 
ATOM   4280 C CG2 . THR B 1 363 ? 143.368 175.455 133.851 1.00 90.64  ? 363 THR B CG2 1 
ATOM   4281 N N   . LYS B 1 364 ? 141.089 174.298 131.674 1.00 84.18  ? 364 LYS B N   1 
ATOM   4282 C CA  . LYS B 1 364 ? 140.940 173.237 130.678 1.00 88.00  ? 364 LYS B CA  1 
ATOM   4283 C C   . LYS B 1 364 ? 142.018 172.173 130.892 1.00 88.93  ? 364 LYS B C   1 
ATOM   4284 O O   . LYS B 1 364 ? 142.965 172.022 130.118 1.00 90.51  ? 364 LYS B O   1 
ATOM   4285 C CB  . LYS B 1 364 ? 140.996 173.811 129.270 1.00 90.68  ? 364 LYS B CB  1 
ATOM   4286 C CG  . LYS B 1 364 ? 139.801 174.668 128.900 1.00 93.13  ? 364 LYS B CG  1 
ATOM   4287 C CD  . LYS B 1 364 ? 139.846 175.059 127.434 1.00 100.45 ? 364 LYS B CD  1 
ATOM   4288 C CE  . LYS B 1 364 ? 138.598 175.823 127.028 1.00 112.14 ? 364 LYS B CE  1 
ATOM   4289 N NZ  . LYS B 1 364 ? 138.586 176.118 125.568 1.00 121.10 ? 364 LYS B NZ  1 
ATOM   4290 N N   . THR B 1 365 ? 141.847 171.414 131.970 1.00 87.86  ? 365 THR B N   1 
ATOM   4291 C CA  . THR B 1 365 ? 142.771 170.341 132.307 1.00 87.15  ? 365 THR B CA  1 
ATOM   4292 C C   . THR B 1 365 ? 142.051 169.349 133.209 1.00 87.30  ? 365 THR B C   1 
ATOM   4293 O O   . THR B 1 365 ? 140.981 169.638 133.750 1.00 89.43  ? 365 THR B O   1 
ATOM   4294 C CB  . THR B 1 365 ? 144.029 170.879 132.987 1.00 88.54  ? 365 THR B CB  1 
ATOM   4295 O OG1 . THR B 1 365 ? 144.938 169.800 133.228 1.00 93.57  ? 365 THR B OG1 1 
ATOM   4296 C CG2 . THR B 1 365 ? 143.666 171.537 134.306 1.00 84.51  ? 365 THR B CG2 1 
ATOM   4297 N N   . PHE B 1 366 ? 142.662 168.173 133.367 1.00 84.21  ? 366 PHE B N   1 
ATOM   4298 C CA  . PHE B 1 366 ? 142.108 167.084 134.175 1.00 82.86  ? 366 PHE B CA  1 
ATOM   4299 C C   . PHE B 1 366 ? 140.763 166.616 133.613 1.00 83.60  ? 366 PHE B C   1 
ATOM   4300 O O   . PHE B 1 366 ? 139.730 166.666 134.281 1.00 82.29  ? 366 PHE B O   1 
ATOM   4301 C CB  . PHE B 1 366 ? 141.973 167.501 135.646 1.00 80.86  ? 366 PHE B CB  1 
ATOM   4302 C CG  . PHE B 1 366 ? 143.258 167.442 136.422 1.00 80.04  ? 366 PHE B CG  1 
ATOM   4303 C CD1 . PHE B 1 366 ? 144.345 168.214 136.057 1.00 79.98  ? 366 PHE B CD1 1 
ATOM   4304 C CD2 . PHE B 1 366 ? 143.368 166.628 137.537 1.00 77.72  ? 366 PHE B CD2 1 
ATOM   4305 C CE1 . PHE B 1 366 ? 145.522 168.161 136.778 1.00 75.22  ? 366 PHE B CE1 1 
ATOM   4306 C CE2 . PHE B 1 366 ? 144.542 166.574 138.262 1.00 75.40  ? 366 PHE B CE2 1 
ATOM   4307 C CZ  . PHE B 1 366 ? 145.619 167.341 137.882 1.00 72.27  ? 366 PHE B CZ  1 
ATOM   4308 N N   . TYR B 1 367 ? 140.798 166.148 132.363 1.00 80.75  ? 367 TYR B N   1 
ATOM   4309 C CA  . TYR B 1 367 ? 139.601 165.694 131.651 1.00 80.26  ? 367 TYR B CA  1 
ATOM   4310 C C   . TYR B 1 367 ? 138.559 166.808 131.562 1.00 79.79  ? 367 TYR B C   1 
ATOM   4311 O O   . TYR B 1 367 ? 137.405 166.638 131.954 1.00 80.46  ? 367 TYR B O   1 
ATOM   4312 C CB  . TYR B 1 367 ? 138.992 164.451 132.308 1.00 79.43  ? 367 TYR B CB  1 
ATOM   4313 C CG  . TYR B 1 367 ? 139.902 163.252 132.432 1.00 78.29  ? 367 TYR B CG  1 
ATOM   4314 C CD1 . TYR B 1 367 ? 140.399 162.615 131.307 1.00 79.71  ? 367 TYR B CD1 1 
ATOM   4315 C CD2 . TYR B 1 367 ? 140.230 162.733 133.678 1.00 74.53  ? 367 TYR B CD2 1 
ATOM   4316 C CE1 . TYR B 1 367 ? 141.219 161.514 131.419 1.00 77.31  ? 367 TYR B CE1 1 
ATOM   4317 C CE2 . TYR B 1 367 ? 141.048 161.631 133.797 1.00 71.24  ? 367 TYR B CE2 1 
ATOM   4318 C CZ  . TYR B 1 367 ? 141.539 161.025 132.665 1.00 70.59  ? 367 TYR B CZ  1 
ATOM   4319 O OH  . TYR B 1 367 ? 142.355 159.924 132.771 1.00 62.68  ? 367 TYR B OH  1 
ATOM   4320 N N   . TYR B 1 368 ? 138.972 167.963 131.039 1.00 79.44  ? 368 TYR B N   1 
ATOM   4321 C CA  . TYR B 1 368 ? 138.092 169.127 131.072 1.00 78.55  ? 368 TYR B CA  1 
ATOM   4322 C C   . TYR B 1 368 ? 136.837 168.913 130.236 1.00 80.39  ? 368 TYR B C   1 
ATOM   4323 O O   . TYR B 1 368 ? 135.736 169.278 130.662 1.00 84.67  ? 368 TYR B O   1 
ATOM   4324 C CB  . TYR B 1 368 ? 138.843 170.378 130.615 1.00 82.57  ? 368 TYR B CB  1 
ATOM   4325 C CG  . TYR B 1 368 ? 139.329 170.346 129.187 1.00 87.72  ? 368 TYR B CG  1 
ATOM   4326 C CD1 . TYR B 1 368 ? 140.483 169.658 128.840 1.00 89.34  ? 368 TYR B CD1 1 
ATOM   4327 C CD2 . TYR B 1 368 ? 138.646 171.023 128.189 1.00 90.03  ? 368 TYR B CD2 1 
ATOM   4328 C CE1 . TYR B 1 368 ? 140.933 169.634 127.538 1.00 90.99  ? 368 TYR B CE1 1 
ATOM   4329 C CE2 . TYR B 1 368 ? 139.090 171.008 126.886 1.00 93.51  ? 368 TYR B CE2 1 
ATOM   4330 C CZ  . TYR B 1 368 ? 140.232 170.309 126.564 1.00 94.12  ? 368 TYR B CZ  1 
ATOM   4331 O OH  . TYR B 1 368 ? 140.676 170.291 125.262 1.00 94.10  ? 368 TYR B OH  1 
ATOM   4332 N N   . LYS B 1 369 ? 136.973 168.322 129.047 1.00 79.37  ? 369 LYS B N   1 
ATOM   4333 C CA  . LYS B 1 369 ? 135.796 168.106 128.210 1.00 81.32  ? 369 LYS B CA  1 
ATOM   4334 C C   . LYS B 1 369 ? 134.800 167.179 128.890 1.00 81.19  ? 369 LYS B C   1 
ATOM   4335 O O   . LYS B 1 369 ? 133.592 167.447 128.901 1.00 81.72  ? 369 LYS B O   1 
ATOM   4336 C CB  . LYS B 1 369 ? 136.208 167.541 126.852 1.00 84.18  ? 369 LYS B CB  1 
ATOM   4337 C CG  . LYS B 1 369 ? 136.936 168.531 125.969 1.00 92.92  ? 369 LYS B CG  1 
ATOM   4338 C CD  . LYS B 1 369 ? 137.264 167.932 124.614 1.00 100.02 ? 369 LYS B CD  1 
ATOM   4339 C CE  . LYS B 1 369 ? 138.017 168.918 123.740 1.00 99.70  ? 369 LYS B CE  1 
ATOM   4340 N NZ  . LYS B 1 369 ? 138.304 168.354 122.394 1.00 106.59 ? 369 LYS B NZ  1 
ATOM   4341 N N   . SER B 1 370 ? 135.294 166.087 129.473 1.00 78.44  ? 370 SER B N   1 
ATOM   4342 C CA  . SER B 1 370 ? 134.417 165.136 130.142 1.00 75.00  ? 370 SER B CA  1 
ATOM   4343 C C   . SER B 1 370 ? 133.718 165.769 131.336 1.00 73.17  ? 370 SER B C   1 
ATOM   4344 O O   . SER B 1 370 ? 132.512 165.576 131.536 1.00 79.83  ? 370 SER B O   1 
ATOM   4345 C CB  . SER B 1 370 ? 135.226 163.920 130.577 1.00 75.01  ? 370 SER B CB  1 
ATOM   4346 O OG  . SER B 1 370 ? 134.454 163.072 131.396 1.00 74.10  ? 370 SER B OG  1 
ATOM   4347 N N   . ARG B 1 371 ? 134.458 166.529 132.141 1.00 67.76  ? 371 ARG B N   1 
ATOM   4348 C CA  . ARG B 1 371 ? 133.854 167.170 133.302 1.00 64.90  ? 371 ARG B CA  1 
ATOM   4349 C C   . ARG B 1 371 ? 132.817 168.203 132.887 1.00 69.31  ? 371 ARG B C   1 
ATOM   4350 O O   . ARG B 1 371 ? 131.769 168.325 133.527 1.00 71.23  ? 371 ARG B O   1 
ATOM   4351 C CB  . ARG B 1 371 ? 134.934 167.811 134.165 1.00 69.93  ? 371 ARG B CB  1 
ATOM   4352 C CG  . ARG B 1 371 ? 135.941 166.825 134.699 1.00 73.38  ? 371 ARG B CG  1 
ATOM   4353 C CD  . ARG B 1 371 ? 137.027 167.512 135.502 1.00 74.77  ? 371 ARG B CD  1 
ATOM   4354 N NE  . ARG B 1 371 ? 137.855 168.411 134.707 1.00 76.68  ? 371 ARG B NE  1 
ATOM   4355 C CZ  . ARG B 1 371 ? 137.755 169.733 134.723 1.00 79.38  ? 371 ARG B CZ  1 
ATOM   4356 N NH1 . ARG B 1 371 ? 136.852 170.348 135.468 1.00 81.38  ? 371 ARG B NH1 1 
ATOM   4357 N NH2 . ARG B 1 371 ? 138.584 170.456 133.979 1.00 82.32  ? 371 ARG B NH2 1 
ATOM   4358 N N   . PHE B 1 372 ? 133.092 168.964 131.825 1.00 71.27  ? 372 PHE B N   1 
ATOM   4359 C CA  . PHE B 1 372 ? 132.117 169.945 131.360 1.00 69.43  ? 372 PHE B CA  1 
ATOM   4360 C C   . PHE B 1 372 ? 130.857 169.262 130.851 1.00 68.01  ? 372 PHE B C   1 
ATOM   4361 O O   . PHE B 1 372 ? 129.740 169.729 131.106 1.00 67.56  ? 372 PHE B O   1 
ATOM   4362 C CB  . PHE B 1 372 ? 132.728 170.830 130.275 1.00 71.93  ? 372 PHE B CB  1 
ATOM   4363 C CG  . PHE B 1 372 ? 133.892 171.653 130.748 1.00 81.47  ? 372 PHE B CG  1 
ATOM   4364 C CD1 . PHE B 1 372 ? 134.058 171.938 132.094 1.00 80.17  ? 372 PHE B CD1 1 
ATOM   4365 C CD2 . PHE B 1 372 ? 134.823 172.139 129.848 1.00 83.38  ? 372 PHE B CD2 1 
ATOM   4366 C CE1 . PHE B 1 372 ? 135.128 172.689 132.531 1.00 76.40  ? 372 PHE B CE1 1 
ATOM   4367 C CE2 . PHE B 1 372 ? 135.894 172.890 130.280 1.00 82.92  ? 372 PHE B CE2 1 
ATOM   4368 C CZ  . PHE B 1 372 ? 136.045 173.166 131.624 1.00 79.97  ? 372 PHE B CZ  1 
ATOM   4369 N N   . TRP B 1 373 ? 131.016 168.149 130.130 1.00 68.95  ? 373 TRP B N   1 
ATOM   4370 C CA  . TRP B 1 373 ? 129.852 167.404 129.664 1.00 67.20  ? 373 TRP B CA  1 
ATOM   4371 C C   . TRP B 1 373 ? 129.030 166.882 130.833 1.00 60.17  ? 373 TRP B C   1 
ATOM   4372 O O   . TRP B 1 373 ? 127.795 166.949 130.814 1.00 62.56  ? 373 TRP B O   1 
ATOM   4373 C CB  . TRP B 1 373 ? 130.296 166.255 128.763 1.00 72.05  ? 373 TRP B CB  1 
ATOM   4374 C CG  . TRP B 1 373 ? 129.174 165.513 128.122 1.00 70.97  ? 373 TRP B CG  1 
ATOM   4375 C CD1 . TRP B 1 373 ? 128.496 165.869 126.996 1.00 74.36  ? 373 TRP B CD1 1 
ATOM   4376 C CD2 . TRP B 1 373 ? 128.606 164.274 128.556 1.00 71.82  ? 373 TRP B CD2 1 
ATOM   4377 N NE1 . TRP B 1 373 ? 127.536 164.933 126.705 1.00 75.16  ? 373 TRP B NE1 1 
ATOM   4378 C CE2 . TRP B 1 373 ? 127.584 163.943 127.649 1.00 73.50  ? 373 TRP B CE2 1 
ATOM   4379 C CE3 . TRP B 1 373 ? 128.860 163.416 129.627 1.00 74.28  ? 373 TRP B CE3 1 
ATOM   4380 C CZ2 . TRP B 1 373 ? 126.818 162.790 127.779 1.00 71.95  ? 373 TRP B CZ2 1 
ATOM   4381 C CZ3 . TRP B 1 373 ? 128.098 162.273 129.754 1.00 72.72  ? 373 TRP B CZ3 1 
ATOM   4382 C CH2 . TRP B 1 373 ? 127.090 161.971 128.837 1.00 72.20  ? 373 TRP B CH2 1 
ATOM   4383 N N   . LEU B 1 374 ? 129.696 166.368 131.868 1.00 58.77  ? 374 LEU B N   1 
ATOM   4384 C CA  . LEU B 1 374 ? 128.966 165.900 133.041 1.00 55.48  ? 374 LEU B CA  1 
ATOM   4385 C C   . LEU B 1 374 ? 128.265 167.049 133.755 1.00 57.72  ? 374 LEU B C   1 
ATOM   4386 O O   . LEU B 1 374 ? 127.154 166.883 134.268 1.00 59.91  ? 374 LEU B O   1 
ATOM   4387 C CB  . LEU B 1 374 ? 129.900 165.172 134.002 1.00 56.37  ? 374 LEU B CB  1 
ATOM   4388 C CG  . LEU B 1 374 ? 129.172 164.677 135.249 1.00 52.10  ? 374 LEU B CG  1 
ATOM   4389 C CD1 . LEU B 1 374 ? 128.120 163.668 134.850 1.00 52.03  ? 374 LEU B CD1 1 
ATOM   4390 C CD2 . LEU B 1 374 ? 130.128 164.090 136.267 1.00 58.56  ? 374 LEU B CD2 1 
ATOM   4391 N N   . LEU B 1 375 ? 128.903 168.219 133.821 1.00 57.51  ? 375 LEU B N   1 
ATOM   4392 C CA  . LEU B 1 375 ? 128.261 169.371 134.445 1.00 57.63  ? 375 LEU B CA  1 
ATOM   4393 C C   . LEU B 1 375 ? 127.008 169.781 133.685 1.00 58.10  ? 375 LEU B C   1 
ATOM   4394 O O   . LEU B 1 375 ? 125.971 170.088 134.291 1.00 59.41  ? 375 LEU B O   1 
ATOM   4395 C CB  . LEU B 1 375 ? 129.242 170.540 134.524 1.00 61.56  ? 375 LEU B CB  1 
ATOM   4396 C CG  . LEU B 1 375 ? 130.363 170.456 135.559 1.00 62.62  ? 375 LEU B CG  1 
ATOM   4397 C CD1 . LEU B 1 375 ? 131.341 171.594 135.361 1.00 65.24  ? 375 LEU B CD1 1 
ATOM   4398 C CD2 . LEU B 1 375 ? 129.792 170.486 136.963 1.00 64.97  ? 375 LEU B CD2 1 
ATOM   4399 N N   . LYS B 1 376 ? 127.083 169.789 132.353 1.00 58.17  ? 376 LYS B N   1 
ATOM   4400 C CA  . LYS B 1 376 ? 125.906 170.122 131.557 1.00 60.06  ? 376 LYS B CA  1 
ATOM   4401 C C   . LYS B 1 376 ? 124.806 169.086 131.745 1.00 61.08  ? 376 LYS B C   1 
ATOM   4402 O O   . LYS B 1 376 ? 123.622 169.433 131.816 1.00 64.35  ? 376 LYS B O   1 
ATOM   4403 C CB  . LYS B 1 376 ? 126.277 170.251 130.081 1.00 61.70  ? 376 LYS B CB  1 
ATOM   4404 C CG  . LYS B 1 376 ? 127.330 171.306 129.796 1.00 65.14  ? 376 LYS B CG  1 
ATOM   4405 C CD  . LYS B 1 376 ? 127.087 172.575 130.595 1.00 71.53  ? 376 LYS B CD  1 
ATOM   4406 C CE  . LYS B 1 376 ? 128.289 173.502 130.532 1.00 74.58  ? 376 LYS B CE  1 
ATOM   4407 N NZ  . LYS B 1 376 ? 128.226 174.570 131.565 1.00 69.32  ? 376 LYS B NZ  1 
ATOM   4408 N N   . LEU B 1 377 ? 125.174 167.807 131.829 1.00 58.90  ? 377 LEU B N   1 
ATOM   4409 C CA  . LEU B 1 377 ? 124.166 166.777 132.060 1.00 55.95  ? 377 LEU B CA  1 
ATOM   4410 C C   . LEU B 1 377 ? 123.524 166.921 133.433 1.00 57.17  ? 377 LEU B C   1 
ATOM   4411 O O   . LEU B 1 377 ? 122.319 166.706 133.578 1.00 63.14  ? 377 LEU B O   1 
ATOM   4412 C CB  . LEU B 1 377 ? 124.772 165.390 131.895 1.00 58.62  ? 377 LEU B CB  1 
ATOM   4413 C CG  . LEU B 1 377 ? 124.345 164.716 130.597 1.00 60.10  ? 377 LEU B CG  1 
ATOM   4414 C CD1 . LEU B 1 377 ? 122.838 164.643 130.535 1.00 61.49  ? 377 LEU B CD1 1 
ATOM   4415 C CD2 . LEU B 1 377 ? 124.886 165.476 129.407 1.00 67.24  ? 377 LEU B CD2 1 
ATOM   4416 N N   . LEU B 1 378 ? 124.310 167.258 134.455 1.00 57.31  ? 378 LEU B N   1 
ATOM   4417 C CA  . LEU B 1 378 ? 123.740 167.486 135.780 1.00 56.44  ? 378 LEU B CA  1 
ATOM   4418 C C   . LEU B 1 378 ? 122.768 168.656 135.764 1.00 58.45  ? 378 LEU B C   1 
ATOM   4419 O O   . LEU B 1 378 ? 121.694 168.592 136.375 1.00 63.19  ? 378 LEU B O   1 
ATOM   4420 C CB  . LEU B 1 378 ? 124.848 167.735 136.800 1.00 57.78  ? 378 LEU B CB  1 
ATOM   4421 C CG  . LEU B 1 378 ? 125.459 166.527 137.506 1.00 60.02  ? 378 LEU B CG  1 
ATOM   4422 C CD1 . LEU B 1 378 ? 126.705 166.935 138.262 1.00 57.37  ? 378 LEU B CD1 1 
ATOM   4423 C CD2 . LEU B 1 378 ? 124.448 165.912 138.450 1.00 62.23  ? 378 LEU B CD2 1 
ATOM   4424 N N   . PHE B 1 379 ? 123.130 169.739 135.075 1.00 56.23  ? 379 PHE B N   1 
ATOM   4425 C CA  . PHE B 1 379 ? 122.218 170.872 134.971 1.00 60.47  ? 379 PHE B CA  1 
ATOM   4426 C C   . PHE B 1 379 ? 120.934 170.488 134.245 1.00 65.15  ? 379 PHE B C   1 
ATOM   4427 O O   . PHE B 1 379 ? 119.838 170.870 134.666 1.00 70.36  ? 379 PHE B O   1 
ATOM   4428 C CB  . PHE B 1 379 ? 122.907 172.037 134.265 1.00 63.86  ? 379 PHE B CB  1 
ATOM   4429 C CG  . PHE B 1 379 ? 121.980 173.163 133.912 1.00 63.96  ? 379 PHE B CG  1 
ATOM   4430 C CD1 . PHE B 1 379 ? 121.419 173.951 134.902 1.00 62.36  ? 379 PHE B CD1 1 
ATOM   4431 C CD2 . PHE B 1 379 ? 121.677 173.438 132.591 1.00 65.70  ? 379 PHE B CD2 1 
ATOM   4432 C CE1 . PHE B 1 379 ? 120.570 174.987 134.579 1.00 64.11  ? 379 PHE B CE1 1 
ATOM   4433 C CE2 . PHE B 1 379 ? 120.829 174.473 132.265 1.00 69.00  ? 379 PHE B CE2 1 
ATOM   4434 C CZ  . PHE B 1 379 ? 120.275 175.248 133.259 1.00 68.03  ? 379 PHE B CZ  1 
ATOM   4435 N N   . ARG B 1 380 ? 121.048 169.727 133.154 1.00 62.02  ? 380 ARG B N   1 
ATOM   4436 C CA  . ARG B 1 380 ? 119.858 169.324 132.410 1.00 61.74  ? 380 ARG B CA  1 
ATOM   4437 C C   . ARG B 1 380 ? 118.983 168.382 133.225 1.00 61.76  ? 380 ARG B C   1 
ATOM   4438 O O   . ARG B 1 380 ? 117.752 168.451 133.153 1.00 67.65  ? 380 ARG B O   1 
ATOM   4439 C CB  . ARG B 1 380 ? 120.254 168.667 131.092 1.00 64.55  ? 380 ARG B CB  1 
ATOM   4440 C CG  . ARG B 1 380 ? 120.907 169.602 130.105 1.00 67.29  ? 380 ARG B CG  1 
ATOM   4441 C CD  . ARG B 1 380 ? 121.436 168.836 128.911 1.00 71.20  ? 380 ARG B CD  1 
ATOM   4442 N NE  . ARG B 1 380 ? 120.401 168.019 128.291 1.00 76.60  ? 380 ARG B NE  1 
ATOM   4443 C CZ  . ARG B 1 380 ? 119.648 168.410 127.271 1.00 79.29  ? 380 ARG B CZ  1 
ATOM   4444 N NH1 . ARG B 1 380 ? 119.795 169.604 126.721 1.00 79.58  ? 380 ARG B NH1 1 
ATOM   4445 N NH2 . ARG B 1 380 ? 118.727 167.580 126.791 1.00 78.63  ? 380 ARG B NH2 1 
ATOM   4446 N N   . VAL B 1 381 ? 119.596 167.479 133.987 1.00 60.37  ? 381 VAL B N   1 
ATOM   4447 C CA  . VAL B 1 381 ? 118.827 166.526 134.777 1.00 62.47  ? 381 VAL B CA  1 
ATOM   4448 C C   . VAL B 1 381 ? 118.108 167.233 135.916 1.00 60.56  ? 381 VAL B C   1 
ATOM   4449 O O   . VAL B 1 381 ? 116.910 167.030 136.133 1.00 68.63  ? 381 VAL B O   1 
ATOM   4450 C CB  . VAL B 1 381 ? 119.742 165.404 135.294 1.00 64.08  ? 381 VAL B CB  1 
ATOM   4451 C CG1 . VAL B 1 381 ? 119.140 164.753 136.527 1.00 60.91  ? 381 VAL B CG1 1 
ATOM   4452 C CG2 . VAL B 1 381 ? 119.962 164.376 134.201 1.00 57.91  ? 381 VAL B CG2 1 
ATOM   4453 N N   . PHE B 1 382 ? 118.818 168.082 136.657 1.00 53.76  ? 382 PHE B N   1 
ATOM   4454 C CA  . PHE B 1 382 ? 118.172 168.746 137.779 1.00 57.34  ? 382 PHE B CA  1 
ATOM   4455 C C   . PHE B 1 382 ? 117.189 169.821 137.342 1.00 63.95  ? 382 PHE B C   1 
ATOM   4456 O O   . PHE B 1 382 ? 116.457 170.346 138.186 1.00 69.40  ? 382 PHE B O   1 
ATOM   4457 C CB  . PHE B 1 382 ? 119.221 169.330 138.718 1.00 62.93  ? 382 PHE B CB  1 
ATOM   4458 C CG  . PHE B 1 382 ? 119.664 168.379 139.787 1.00 63.49  ? 382 PHE B CG  1 
ATOM   4459 C CD1 . PHE B 1 382 ? 120.600 167.399 139.515 1.00 64.98  ? 382 PHE B CD1 1 
ATOM   4460 C CD2 . PHE B 1 382 ? 119.139 168.459 141.064 1.00 62.58  ? 382 PHE B CD2 1 
ATOM   4461 C CE1 . PHE B 1 382 ? 121.008 166.521 140.499 1.00 64.77  ? 382 PHE B CE1 1 
ATOM   4462 C CE2 . PHE B 1 382 ? 119.544 167.583 142.051 1.00 63.15  ? 382 PHE B CE2 1 
ATOM   4463 C CZ  . PHE B 1 382 ? 120.479 166.614 141.767 1.00 66.19  ? 382 PHE B CZ  1 
ATOM   4464 N N   . THR B 1 383 ? 117.154 170.160 136.057 1.00 64.54  ? 383 THR B N   1 
ATOM   4465 C CA  . THR B 1 383 ? 116.111 171.022 135.519 1.00 71.95  ? 383 THR B CA  1 
ATOM   4466 C C   . THR B 1 383 ? 115.342 170.252 134.455 1.00 78.64  ? 383 THR B C   1 
ATOM   4467 O O   . THR B 1 383 ? 115.096 170.762 133.359 1.00 81.45  ? 383 THR B O   1 
ATOM   4468 C CB  . THR B 1 383 ? 116.705 172.303 134.939 1.00 68.13  ? 383 THR B CB  1 
ATOM   4469 O OG1 . THR B 1 383 ? 117.571 171.976 133.847 1.00 62.57  ? 383 THR B OG1 1 
ATOM   4470 C CG2 . THR B 1 383 ? 117.500 173.040 136.000 1.00 66.87  ? 383 THR B CG2 1 
ATOM   4471 N N   . ALA B 1 384 ? 114.968 169.016 134.785 1.00 75.26  ? 384 ALA B N   1 
ATOM   4472 C CA  . ALA B 1 384 ? 114.441 168.090 133.785 1.00 73.29  ? 384 ALA B CA  1 
ATOM   4473 C C   . ALA B 1 384 ? 113.205 168.578 133.038 1.00 81.48  ? 384 ALA B C   1 
ATOM   4474 O O   . ALA B 1 384 ? 113.178 168.434 131.803 1.00 80.93  ? 384 ALA B O   1 
ATOM   4475 C CB  . ALA B 1 384 ? 114.153 166.737 134.446 1.00 72.13  ? 384 ALA B CB  1 
ATOM   4476 N N   . PRO B 1 385 ? 112.165 169.125 133.682 1.00 81.90  ? 385 PRO B N   1 
ATOM   4477 C CA  . PRO B 1 385 ? 110.935 169.435 132.932 1.00 77.08  ? 385 PRO B CA  1 
ATOM   4478 C C   . PRO B 1 385 ? 111.119 170.451 131.825 1.00 78.63  ? 385 PRO B C   1 
ATOM   4479 O O   . PRO B 1 385 ? 110.309 170.474 130.892 1.00 79.04  ? 385 PRO B O   1 
ATOM   4480 C CB  . PRO B 1 385 ? 109.984 169.966 134.014 1.00 70.07  ? 385 PRO B CB  1 
ATOM   4481 C CG  . PRO B 1 385 ? 110.861 170.390 135.118 1.00 72.68  ? 385 PRO B CG  1 
ATOM   4482 C CD  . PRO B 1 385 ? 112.013 169.449 135.111 1.00 72.76  ? 385 PRO B CD  1 
ATOM   4483 N N   . PHE B 1 386 ? 112.153 171.286 131.885 1.00 79.56  ? 386 PHE B N   1 
ATOM   4484 C CA  . PHE B 1 386 ? 112.317 172.380 130.940 1.00 82.21  ? 386 PHE B CA  1 
ATOM   4485 C C   . PHE B 1 386 ? 113.269 172.043 129.802 1.00 82.57  ? 386 PHE B C   1 
ATOM   4486 O O   . PHE B 1 386 ? 113.581 172.920 128.990 1.00 84.24  ? 386 PHE B O   1 
ATOM   4487 C CB  . PHE B 1 386 ? 112.795 173.633 131.673 1.00 82.69  ? 386 PHE B CB  1 
ATOM   4488 C CG  . PHE B 1 386 ? 112.024 173.928 132.926 1.00 81.96  ? 386 PHE B CG  1 
ATOM   4489 C CD1 . PHE B 1 386 ? 110.803 174.577 132.868 1.00 84.23  ? 386 PHE B CD1 1 
ATOM   4490 C CD2 . PHE B 1 386 ? 112.519 173.555 134.165 1.00 77.37  ? 386 PHE B CD2 1 
ATOM   4491 C CE1 . PHE B 1 386 ? 110.092 174.849 134.020 1.00 83.75  ? 386 PHE B CE1 1 
ATOM   4492 C CE2 . PHE B 1 386 ? 111.815 173.825 135.320 1.00 77.18  ? 386 PHE B CE2 1 
ATOM   4493 C CZ  . PHE B 1 386 ? 110.599 174.472 135.248 1.00 81.46  ? 386 PHE B CZ  1 
ATOM   4494 N N   . HIS B 1 387 ? 113.727 170.799 129.709 1.00 81.64  ? 387 HIS B N   1 
ATOM   4495 C CA  . HIS B 1 387 ? 114.655 170.390 128.666 1.00 84.03  ? 387 HIS B CA  1 
ATOM   4496 C C   . HIS B 1 387 ? 114.140 169.142 127.967 1.00 82.97  ? 387 HIS B C   1 
ATOM   4497 O O   . HIS B 1 387 ? 113.515 168.277 128.585 1.00 82.92  ? 387 HIS B O   1 
ATOM   4498 C CB  . HIS B 1 387 ? 116.051 170.105 129.227 1.00 82.99  ? 387 HIS B CB  1 
ATOM   4499 C CG  . HIS B 1 387 ? 116.720 171.300 129.827 1.00 78.08  ? 387 HIS B CG  1 
ATOM   4500 N ND1 . HIS B 1 387 ? 117.619 172.076 129.129 1.00 77.73  ? 387 HIS B ND1 1 
ATOM   4501 C CD2 . HIS B 1 387 ? 116.632 171.844 131.062 1.00 73.64  ? 387 HIS B CD2 1 
ATOM   4502 C CE1 . HIS B 1 387 ? 118.052 173.051 129.908 1.00 76.95  ? 387 HIS B CE1 1 
ATOM   4503 N NE2 . HIS B 1 387 ? 117.469 172.932 131.087 1.00 74.80  ? 387 HIS B NE2 1 
ATOM   4504 N N   . LYS B 1 388 ? 114.412 169.059 126.668 1.00 79.41  ? 388 LYS B N   1 
ATOM   4505 C CA  . LYS B 1 388 ? 114.113 167.845 125.925 1.00 80.56  ? 388 LYS B CA  1 
ATOM   4506 C C   . LYS B 1 388 ? 114.912 166.684 126.500 1.00 82.91  ? 388 LYS B C   1 
ATOM   4507 O O   . LYS B 1 388 ? 116.111 166.809 126.760 1.00 82.96  ? 388 LYS B O   1 
ATOM   4508 C CB  . LYS B 1 388 ? 114.440 168.040 124.446 1.00 82.47  ? 388 LYS B CB  1 
ATOM   4509 C CG  . LYS B 1 388 ? 114.426 166.761 123.631 1.00 85.54  ? 388 LYS B CG  1 
ATOM   4510 C CD  . LYS B 1 388 ? 113.028 166.185 123.529 1.00 92.93  ? 388 LYS B CD  1 
ATOM   4511 C CE  . LYS B 1 388 ? 112.116 167.100 122.729 1.00 99.97  ? 388 LYS B CE  1 
ATOM   4512 N NZ  . LYS B 1 388 ? 110.746 166.536 122.590 1.00 99.17  ? 388 LYS B NZ  1 
ATOM   4513 N N   . VAL B 1 389 ? 114.245 165.552 126.703 1.00 83.24  ? 389 VAL B N   1 
ATOM   4514 C CA  . VAL B 1 389 ? 114.848 164.412 127.383 1.00 77.66  ? 389 VAL B CA  1 
ATOM   4515 C C   . VAL B 1 389 ? 115.571 163.571 126.337 1.00 77.40  ? 389 VAL B C   1 
ATOM   4516 O O   . VAL B 1 389 ? 114.954 162.789 125.613 1.00 76.90  ? 389 VAL B O   1 
ATOM   4517 C CB  . VAL B 1 389 ? 113.809 163.590 128.144 1.00 70.45  ? 389 VAL B CB  1 
ATOM   4518 C CG1 . VAL B 1 389 ? 114.479 162.417 128.821 1.00 68.46  ? 389 VAL B CG1 1 
ATOM   4519 C CG2 . VAL B 1 389 ? 113.097 164.456 129.164 1.00 73.19  ? 389 VAL B CG2 1 
ATOM   4520 N N   . GLY B 1 390 ? 116.890 163.733 126.262 1.00 77.69  ? 390 GLY B N   1 
ATOM   4521 C CA  . GLY B 1 390 ? 117.723 162.836 125.494 1.00 76.74  ? 390 GLY B CA  1 
ATOM   4522 C C   . GLY B 1 390 ? 118.078 161.602 126.296 1.00 76.04  ? 390 GLY B C   1 
ATOM   4523 O O   . GLY B 1 390 ? 117.707 161.448 127.459 1.00 75.87  ? 390 GLY B O   1 
ATOM   4524 N N   . PHE B 1 391 ? 118.816 160.695 125.652 1.00 74.25  ? 391 PHE B N   1 
ATOM   4525 C CA  . PHE B 1 391 ? 119.165 159.449 126.324 1.00 72.14  ? 391 PHE B CA  1 
ATOM   4526 C C   . PHE B 1 391 ? 120.076 159.694 127.517 1.00 68.32  ? 391 PHE B C   1 
ATOM   4527 O O   . PHE B 1 391 ? 119.918 159.058 128.563 1.00 65.26  ? 391 PHE B O   1 
ATOM   4528 C CB  . PHE B 1 391 ? 119.829 158.471 125.362 1.00 69.26  ? 391 PHE B CB  1 
ATOM   4529 C CG  . PHE B 1 391 ? 120.256 157.198 126.023 1.00 63.49  ? 391 PHE B CG  1 
ATOM   4530 C CD1 . PHE B 1 391 ? 119.337 156.198 126.273 1.00 65.37  ? 391 PHE B CD1 1 
ATOM   4531 C CD2 . PHE B 1 391 ? 121.564 157.011 126.420 1.00 64.29  ? 391 PHE B CD2 1 
ATOM   4532 C CE1 . PHE B 1 391 ? 119.717 155.031 126.893 1.00 64.72  ? 391 PHE B CE1 1 
ATOM   4533 C CE2 . PHE B 1 391 ? 121.947 155.845 127.043 1.00 62.15  ? 391 PHE B CE2 1 
ATOM   4534 C CZ  . PHE B 1 391 ? 121.020 154.856 127.280 1.00 60.74  ? 391 PHE B CZ  1 
ATOM   4535 N N   . ALA B 1 392 ? 121.048 160.596 127.372 1.00 66.59  ? 392 ALA B N   1 
ATOM   4536 C CA  . ALA B 1 392 ? 121.980 160.856 128.463 1.00 65.38  ? 392 ALA B CA  1 
ATOM   4537 C C   . ALA B 1 392 ? 121.260 161.411 129.682 1.00 66.62  ? 392 ALA B C   1 
ATOM   4538 O O   . ALA B 1 392 ? 121.568 161.035 130.820 1.00 61.88  ? 392 ALA B O   1 
ATOM   4539 C CB  . ALA B 1 392 ? 123.075 161.815 128.000 1.00 61.12  ? 392 ALA B CB  1 
ATOM   4540 N N   . ASP B 1 393 ? 120.292 162.303 129.462 1.00 69.94  ? 393 ASP B N   1 
ATOM   4541 C CA  . ASP B 1 393 ? 119.541 162.885 130.569 1.00 65.88  ? 393 ASP B CA  1 
ATOM   4542 C C   . ASP B 1 393 ? 118.806 161.808 131.356 1.00 63.34  ? 393 ASP B C   1 
ATOM   4543 O O   . ASP B 1 393 ? 118.920 161.732 132.586 1.00 64.43  ? 393 ASP B O   1 
ATOM   4544 C CB  . ASP B 1 393 ? 118.556 163.924 130.034 1.00 68.73  ? 393 ASP B CB  1 
ATOM   4545 C CG  . ASP B 1 393 ? 119.128 164.736 128.884 1.00 72.71  ? 393 ASP B CG  1 
ATOM   4546 O OD1 . ASP B 1 393 ? 120.292 164.497 128.504 1.00 73.18  ? 393 ASP B OD1 1 
ATOM   4547 O OD2 . ASP B 1 393 ? 118.411 165.611 128.355 1.00 76.37  ? 393 ASP B OD2 1 
ATOM   4548 N N   . PHE B 1 394 ? 118.055 160.954 130.657 1.00 60.07  ? 394 PHE B N   1 
ATOM   4549 C CA  . PHE B 1 394 ? 117.324 159.885 131.325 1.00 61.71  ? 394 PHE B CA  1 
ATOM   4550 C C   . PHE B 1 394 ? 118.277 158.923 132.017 1.00 60.46  ? 394 PHE B C   1 
ATOM   4551 O O   . PHE B 1 394 ? 118.027 158.481 133.143 1.00 59.97  ? 394 PHE B O   1 
ATOM   4552 C CB  . PHE B 1 394 ? 116.450 159.128 130.323 1.00 62.27  ? 394 PHE B CB  1 
ATOM   4553 C CG  . PHE B 1 394 ? 116.424 157.642 130.553 1.00 62.78  ? 394 PHE B CG  1 
ATOM   4554 C CD1 . PHE B 1 394 ? 115.714 157.099 131.607 1.00 60.01  ? 394 PHE B CD1 1 
ATOM   4555 C CD2 . PHE B 1 394 ? 117.118 156.788 129.718 1.00 68.78  ? 394 PHE B CD2 1 
ATOM   4556 C CE1 . PHE B 1 394 ? 115.700 155.741 131.824 1.00 59.92  ? 394 PHE B CE1 1 
ATOM   4557 C CE2 . PHE B 1 394 ? 117.102 155.428 129.932 1.00 68.53  ? 394 PHE B CE2 1 
ATOM   4558 C CZ  . PHE B 1 394 ? 116.393 154.906 130.986 1.00 64.45  ? 394 PHE B CZ  1 
ATOM   4559 N N   . TRP B 1 395 ? 119.371 158.571 131.344 1.00 58.08  ? 395 TRP B N   1 
ATOM   4560 C CA  . TRP B 1 395 ? 120.302 157.597 131.896 1.00 55.71  ? 395 TRP B CA  1 
ATOM   4561 C C   . TRP B 1 395 ? 120.908 158.102 133.198 1.00 57.12  ? 395 TRP B C   1 
ATOM   4562 O O   . TRP B 1 395 ? 120.924 157.387 134.204 1.00 56.81  ? 395 TRP B O   1 
ATOM   4563 C CB  . TRP B 1 395 ? 121.383 157.282 130.866 1.00 54.21  ? 395 TRP B CB  1 
ATOM   4564 C CG  . TRP B 1 395 ? 122.310 156.191 131.265 1.00 54.04  ? 395 TRP B CG  1 
ATOM   4565 C CD1 . TRP B 1 395 ? 122.060 154.853 131.236 1.00 52.25  ? 395 TRP B CD1 1 
ATOM   4566 C CD2 . TRP B 1 395 ? 123.653 156.341 131.733 1.00 49.90  ? 395 TRP B CD2 1 
ATOM   4567 N NE1 . TRP B 1 395 ? 123.163 154.159 131.670 1.00 50.11  ? 395 TRP B NE1 1 
ATOM   4568 C CE2 . TRP B 1 395 ? 124.154 155.052 131.981 1.00 46.44  ? 395 TRP B CE2 1 
ATOM   4569 C CE3 . TRP B 1 395 ? 124.475 157.441 131.976 1.00 48.79  ? 395 TRP B CE3 1 
ATOM   4570 C CZ2 . TRP B 1 395 ? 125.438 154.836 132.454 1.00 43.98  ? 395 TRP B CZ2 1 
ATOM   4571 C CZ3 . TRP B 1 395 ? 125.744 157.223 132.445 1.00 46.07  ? 395 TRP B CZ3 1 
ATOM   4572 C CH2 . TRP B 1 395 ? 126.215 155.932 132.681 1.00 43.98  ? 395 TRP B CH2 1 
ATOM   4573 N N   . LEU B 1 396 ? 121.377 159.351 133.208 1.00 56.41  ? 396 LEU B N   1 
ATOM   4574 C CA  . LEU B 1 396 ? 121.945 159.909 134.430 1.00 53.38  ? 396 LEU B CA  1 
ATOM   4575 C C   . LEU B 1 396 ? 120.891 160.083 135.516 1.00 53.75  ? 396 LEU B C   1 
ATOM   4576 O O   . LEU B 1 396 ? 121.164 159.809 136.693 1.00 56.53  ? 396 LEU B O   1 
ATOM   4577 C CB  . LEU B 1 396 ? 122.631 161.237 134.125 1.00 52.68  ? 396 LEU B CB  1 
ATOM   4578 C CG  . LEU B 1 396 ? 123.237 162.017 135.290 1.00 52.65  ? 396 LEU B CG  1 
ATOM   4579 C CD1 . LEU B 1 396 ? 124.098 161.123 136.160 1.00 50.10  ? 396 LEU B CD1 1 
ATOM   4580 C CD2 . LEU B 1 396 ? 124.054 163.178 134.755 1.00 50.92  ? 396 LEU B CD2 1 
ATOM   4581 N N   . ALA B 1 397 ? 119.688 160.530 135.155 1.00 50.96  ? 397 ALA B N   1 
ATOM   4582 C CA  . ALA B 1 397 ? 118.623 160.664 136.134 1.00 48.19  ? 397 ALA B CA  1 
ATOM   4583 C C   . ALA B 1 397 ? 118.204 159.333 136.731 1.00 52.73  ? 397 ALA B C   1 
ATOM   4584 O O   . ALA B 1 397 ? 117.728 159.306 137.870 1.00 58.22  ? 397 ALA B O   1 
ATOM   4585 C CB  . ALA B 1 397 ? 117.406 161.343 135.504 1.00 51.29  ? 397 ALA B CB  1 
ATOM   4586 N N   . ASP B 1 398 ? 118.363 158.236 135.994 1.00 52.33  ? 398 ASP B N   1 
ATOM   4587 C CA  . ASP B 1 398 ? 118.081 156.914 136.531 1.00 49.70  ? 398 ASP B CA  1 
ATOM   4588 C C   . ASP B 1 398 ? 119.242 156.343 137.333 1.00 52.84  ? 398 ASP B C   1 
ATOM   4589 O O   . ASP B 1 398 ? 119.008 155.564 138.260 1.00 58.92  ? 398 ASP B O   1 
ATOM   4590 C CB  . ASP B 1 398 ? 117.716 155.954 135.402 1.00 50.22  ? 398 ASP B CB  1 
ATOM   4591 C CG  . ASP B 1 398 ? 116.710 154.918 135.833 1.00 55.85  ? 398 ASP B CG  1 
ATOM   4592 O OD1 . ASP B 1 398 ? 116.716 154.555 137.024 1.00 62.17  ? 398 ASP B OD1 1 
ATOM   4593 O OD2 . ASP B 1 398 ? 115.911 154.468 134.988 1.00 53.64  ? 398 ASP B OD2 1 
ATOM   4594 N N   . GLN B 1 399 ? 120.482 156.703 136.995 1.00 50.86  ? 399 GLN B N   1 
ATOM   4595 C CA  . GLN B 1 399 ? 121.609 156.353 137.856 1.00 48.05  ? 399 GLN B CA  1 
ATOM   4596 C C   . GLN B 1 399 ? 121.481 157.025 139.216 1.00 53.39  ? 399 GLN B C   1 
ATOM   4597 O O   . GLN B 1 399 ? 121.816 156.430 140.248 1.00 56.91  ? 399 GLN B O   1 
ATOM   4598 C CB  . GLN B 1 399 ? 122.929 156.752 137.204 1.00 44.43  ? 399 GLN B CB  1 
ATOM   4599 C CG  . GLN B 1 399 ? 123.134 156.215 135.819 1.00 43.65  ? 399 GLN B CG  1 
ATOM   4600 C CD  . GLN B 1 399 ? 123.359 154.737 135.806 1.00 48.49  ? 399 GLN B CD  1 
ATOM   4601 O OE1 . GLN B 1 399 ? 122.872 154.034 134.928 1.00 55.76  ? 399 GLN B OE1 1 
ATOM   4602 N NE2 . GLN B 1 399 ? 124.114 154.250 136.776 1.00 45.92  ? 399 GLN B NE2 1 
ATOM   4603 N N   . LEU B 1 400 ? 121.015 158.274 139.235 1.00 54.72  ? 400 LEU B N   1 
ATOM   4604 C CA  . LEU B 1 400 ? 120.815 158.951 140.512 1.00 53.07  ? 400 LEU B CA  1 
ATOM   4605 C C   . LEU B 1 400 ? 119.798 158.222 141.377 1.00 56.42  ? 400 LEU B C   1 
ATOM   4606 O O   . LEU B 1 400 ? 119.866 158.291 142.610 1.00 60.06  ? 400 LEU B O   1 
ATOM   4607 C CB  . LEU B 1 400 ? 120.374 160.395 140.292 1.00 55.18  ? 400 LEU B CB  1 
ATOM   4608 C CG  . LEU B 1 400 ? 121.420 161.365 139.755 1.00 54.87  ? 400 LEU B CG  1 
ATOM   4609 C CD1 . LEU B 1 400 ? 120.931 162.792 139.924 1.00 58.80  ? 400 LEU B CD1 1 
ATOM   4610 C CD2 . LEU B 1 400 ? 122.749 161.160 140.453 1.00 57.58  ? 400 LEU B CD2 1 
ATOM   4611 N N   . ASN B 1 401 ? 118.855 157.514 140.757 1.00 57.04  ? 401 ASN B N   1 
ATOM   4612 C CA  . ASN B 1 401 ? 117.882 156.750 141.528 1.00 58.34  ? 401 ASN B CA  1 
ATOM   4613 C C   . ASN B 1 401 ? 118.567 155.674 142.362 1.00 55.85  ? 401 ASN B C   1 
ATOM   4614 O O   . ASN B 1 401 ? 118.206 155.453 143.524 1.00 57.33  ? 401 ASN B O   1 
ATOM   4615 C CB  . ASN B 1 401 ? 116.847 156.135 140.591 1.00 59.62  ? 401 ASN B CB  1 
ATOM   4616 C CG  . ASN B 1 401 ? 115.464 156.114 141.191 1.00 71.32  ? 401 ASN B CG  1 
ATOM   4617 O OD1 . ASN B 1 401 ? 114.743 157.107 141.144 1.00 70.98  ? 401 ASN B OD1 1 
ATOM   4618 N ND2 . ASN B 1 401 ? 115.079 154.977 141.752 1.00 72.14  ? 401 ASN B ND2 1 
ATOM   4619 N N   . SER B 1 402 ? 119.560 154.997 141.789 1.00 56.84  ? 402 SER B N   1 
ATOM   4620 C CA  . SER B 1 402 ? 120.327 154.017 142.543 1.00 61.43  ? 402 SER B CA  1 
ATOM   4621 C C   . SER B 1 402 ? 121.384 154.656 143.431 1.00 65.73  ? 402 SER B C   1 
ATOM   4622 O O   . SER B 1 402 ? 121.866 154.004 144.362 1.00 70.31  ? 402 SER B O   1 
ATOM   4623 C CB  . SER B 1 402 ? 120.999 153.025 141.592 1.00 50.91  ? 402 SER B CB  1 
ATOM   4624 O OG  . SER B 1 402 ? 120.038 152.303 140.844 1.00 51.45  ? 402 SER B OG  1 
ATOM   4625 N N   . LEU B 1 403 ? 121.761 155.903 143.161 1.00 65.14  ? 403 LEU B N   1 
ATOM   4626 C CA  . LEU B 1 403 ? 122.807 156.573 143.926 1.00 60.87  ? 403 LEU B CA  1 
ATOM   4627 C C   . LEU B 1 403 ? 122.276 157.494 145.022 1.00 61.16  ? 403 LEU B C   1 
ATOM   4628 O O   . LEU B 1 403 ? 123.074 158.151 145.692 1.00 66.74  ? 403 LEU B O   1 
ATOM   4629 C CB  . LEU B 1 403 ? 123.707 157.371 142.980 1.00 61.85  ? 403 LEU B CB  1 
ATOM   4630 C CG  . LEU B 1 403 ? 125.172 157.518 143.375 1.00 61.20  ? 403 LEU B CG  1 
ATOM   4631 C CD1 . LEU B 1 403 ? 125.824 156.156 143.444 1.00 57.50  ? 403 LEU B CD1 1 
ATOM   4632 C CD2 . LEU B 1 403 ? 125.894 158.416 142.388 1.00 60.58  ? 403 LEU B CD2 1 
ATOM   4633 N N   . SER B 1 404 ? 120.958 157.565 145.212 1.00 60.26  ? 404 SER B N   1 
ATOM   4634 C CA  . SER B 1 404 ? 120.349 158.468 146.190 1.00 66.00  ? 404 SER B CA  1 
ATOM   4635 C C   . SER B 1 404 ? 120.962 158.402 147.589 1.00 70.25  ? 404 SER B C   1 
ATOM   4636 O O   . SER B 1 404 ? 120.771 159.345 148.371 1.00 73.46  ? 404 SER B O   1 
ATOM   4637 C CB  . SER B 1 404 ? 118.855 158.176 146.303 1.00 66.78  ? 404 SER B CB  1 
ATOM   4638 O OG  . SER B 1 404 ? 118.628 156.904 146.881 1.00 72.24  ? 404 SER B OG  1 
ATOM   4639 N N   . VAL B 1 405 ? 121.664 157.323 147.941 1.00 69.14  ? 405 VAL B N   1 
ATOM   4640 C CA  . VAL B 1 405 ? 122.236 157.241 149.282 1.00 72.69  ? 405 VAL B CA  1 
ATOM   4641 C C   . VAL B 1 405 ? 123.290 158.320 149.480 1.00 73.43  ? 405 VAL B C   1 
ATOM   4642 O O   . VAL B 1 405 ? 123.514 158.784 150.605 1.00 79.87  ? 405 VAL B O   1 
ATOM   4643 C CB  . VAL B 1 405 ? 122.806 155.836 149.540 1.00 71.68  ? 405 VAL B CB  1 
ATOM   4644 C CG1 . VAL B 1 405 ? 123.042 155.630 151.025 1.00 75.68  ? 405 VAL B CG1 1 
ATOM   4645 C CG2 . VAL B 1 405 ? 121.870 154.774 148.985 1.00 67.27  ? 405 VAL B CG2 1 
ATOM   4646 N N   . ILE B 1 406 ? 123.944 158.744 148.400 1.00 68.51  ? 406 ILE B N   1 
ATOM   4647 C CA  . ILE B 1 406 ? 124.892 159.849 148.495 1.00 66.79  ? 406 ILE B CA  1 
ATOM   4648 C C   . ILE B 1 406 ? 124.183 161.124 148.930 1.00 70.55  ? 406 ILE B C   1 
ATOM   4649 O O   . ILE B 1 406 ? 124.659 161.842 149.816 1.00 75.53  ? 406 ILE B O   1 
ATOM   4650 C CB  . ILE B 1 406 ? 125.625 160.031 147.155 1.00 68.39  ? 406 ILE B CB  1 
ATOM   4651 C CG1 . ILE B 1 406 ? 126.673 158.936 146.976 1.00 66.48  ? 406 ILE B CG1 1 
ATOM   4652 C CG2 . ILE B 1 406 ? 126.262 161.400 147.072 1.00 72.64  ? 406 ILE B CG2 1 
ATOM   4653 C CD1 . ILE B 1 406 ? 127.495 159.088 145.726 1.00 63.81  ? 406 ILE B CD1 1 
ATOM   4654 N N   . LEU B 1 407 ? 123.032 161.423 148.322 1.00 69.66  ? 407 LEU B N   1 
ATOM   4655 C CA  . LEU B 1 407 ? 122.264 162.598 148.723 1.00 69.27  ? 407 LEU B CA  1 
ATOM   4656 C C   . LEU B 1 407 ? 121.795 162.476 150.164 1.00 74.99  ? 407 LEU B C   1 
ATOM   4657 O O   . LEU B 1 407 ? 121.798 163.459 150.917 1.00 80.81  ? 407 LEU B O   1 
ATOM   4658 C CB  . LEU B 1 407 ? 121.067 162.783 147.793 1.00 68.53  ? 407 LEU B CB  1 
ATOM   4659 C CG  . LEU B 1 407 ? 121.343 163.209 146.351 1.00 72.24  ? 407 LEU B CG  1 
ATOM   4660 C CD1 . LEU B 1 407 ? 120.309 162.620 145.418 1.00 66.19  ? 407 LEU B CD1 1 
ATOM   4661 C CD2 . LEU B 1 407 ? 121.338 164.721 146.247 1.00 76.48  ? 407 LEU B CD2 1 
ATOM   4662 N N   . MET B 1 408 ? 121.373 161.277 150.557 1.00 77.19  ? 408 MET B N   1 
ATOM   4663 C CA  . MET B 1 408 ? 120.947 161.058 151.935 1.00 81.45  ? 408 MET B CA  1 
ATOM   4664 C C   . MET B 1 408 ? 122.066 161.361 152.921 1.00 87.03  ? 408 MET B C   1 
ATOM   4665 O O   . MET B 1 408 ? 121.855 162.069 153.913 1.00 93.79  ? 408 MET B O   1 
ATOM   4666 C CB  . MET B 1 408 ? 120.468 159.620 152.109 1.00 80.46  ? 408 MET B CB  1 
ATOM   4667 C CG  . MET B 1 408 ? 119.314 159.271 151.210 1.00 83.91  ? 408 MET B CG  1 
ATOM   4668 S SD  . MET B 1 408 ? 117.960 160.403 151.514 1.00 101.20 ? 408 MET B SD  1 
ATOM   4669 C CE  . MET B 1 408 ? 117.662 160.048 153.237 1.00 97.96  ? 408 MET B CE  1 
ATOM   4670 N N   . ASP B 1 409 ? 123.267 160.848 152.653 1.00 83.84  ? 409 ASP B N   1 
ATOM   4671 C CA  . ASP B 1 409 ? 124.390 161.107 153.544 1.00 82.08  ? 409 ASP B CA  1 
ATOM   4672 C C   . ASP B 1 409 ? 124.819 162.566 153.499 1.00 88.59  ? 409 ASP B C   1 
ATOM   4673 O O   . ASP B 1 409 ? 125.274 163.101 154.512 1.00 94.64  ? 409 ASP B O   1 
ATOM   4674 C CB  . ASP B 1 409 ? 125.559 160.192 153.195 1.00 79.83  ? 409 ASP B CB  1 
ATOM   4675 C CG  . ASP B 1 409 ? 125.327 158.770 153.647 1.00 79.74  ? 409 ASP B CG  1 
ATOM   4676 O OD1 . ASP B 1 409 ? 124.289 158.518 154.291 1.00 77.33  ? 409 ASP B OD1 1 
ATOM   4677 O OD2 . ASP B 1 409 ? 126.176 157.904 153.362 1.00 77.91  ? 409 ASP B OD2 1 
ATOM   4678 N N   . LEU B 1 410 ? 124.688 163.223 152.345 1.00 89.36  ? 410 LEU B N   1 
ATOM   4679 C CA  . LEU B 1 410 ? 125.007 164.645 152.269 1.00 88.91  ? 410 LEU B CA  1 
ATOM   4680 C C   . LEU B 1 410 ? 124.077 165.464 153.155 1.00 93.56  ? 410 LEU B C   1 
ATOM   4681 O O   . LEU B 1 410 ? 124.527 166.352 153.889 1.00 95.60  ? 410 LEU B O   1 
ATOM   4682 C CB  . LEU B 1 410 ? 124.928 165.117 150.820 1.00 85.54  ? 410 LEU B CB  1 
ATOM   4683 C CG  . LEU B 1 410 ? 125.114 166.610 150.567 1.00 86.43  ? 410 LEU B CG  1 
ATOM   4684 C CD1 . LEU B 1 410 ? 126.412 167.094 151.184 1.00 92.07  ? 410 LEU B CD1 1 
ATOM   4685 C CD2 . LEU B 1 410 ? 125.089 166.887 149.072 1.00 84.65  ? 410 LEU B CD2 1 
ATOM   4686 N N   . GLU B 1 411 ? 122.776 165.173 153.110 1.00 96.42  ? 411 GLU B N   1 
ATOM   4687 C CA  . GLU B 1 411 ? 121.845 165.868 153.995 1.00 98.39  ? 411 GLU B CA  1 
ATOM   4688 C C   . GLU B 1 411 ? 122.108 165.532 155.457 1.00 100.94 ? 411 GLU B C   1 
ATOM   4689 O O   . GLU B 1 411 ? 121.990 166.406 156.326 1.00 105.62 ? 411 GLU B O   1 
ATOM   4690 C CB  . GLU B 1 411 ? 120.402 165.531 153.624 1.00 98.10  ? 411 GLU B CB  1 
ATOM   4691 C CG  . GLU B 1 411 ? 119.364 166.365 154.361 1.00 104.18 ? 411 GLU B CG  1 
ATOM   4692 C CD  . GLU B 1 411 ? 119.349 167.817 153.914 1.00 109.74 ? 411 GLU B CD  1 
ATOM   4693 O OE1 . GLU B 1 411 ? 119.947 168.129 152.863 1.00 110.22 ? 411 GLU B OE1 1 
ATOM   4694 O OE2 . GLU B 1 411 ? 118.732 168.648 154.613 1.00 108.57 ? 411 GLU B OE2 1 
ATOM   4695 N N   . TYR B 1 412 ? 122.458 164.278 155.749 1.00 100.08 ? 412 TYR B N   1 
ATOM   4696 C CA  . TYR B 1 412 ? 122.810 163.915 157.117 1.00 103.47 ? 412 TYR B CA  1 
ATOM   4697 C C   . TYR B 1 412 ? 124.021 164.705 157.593 1.00 107.82 ? 412 TYR B C   1 
ATOM   4698 O O   . TYR B 1 412 ? 124.073 165.152 158.741 1.00 112.87 ? 412 TYR B O   1 
ATOM   4699 C CB  . TYR B 1 412 ? 123.079 162.415 157.223 1.00 104.04 ? 412 TYR B CB  1 
ATOM   4700 C CG  . TYR B 1 412 ? 123.676 162.018 158.555 1.00 107.32 ? 412 TYR B CG  1 
ATOM   4701 C CD1 . TYR B 1 412 ? 122.887 161.937 159.693 1.00 109.00 ? 412 TYR B CD1 1 
ATOM   4702 C CD2 . TYR B 1 412 ? 125.029 161.734 158.677 1.00 101.50 ? 412 TYR B CD2 1 
ATOM   4703 C CE1 . TYR B 1 412 ? 123.426 161.581 160.912 1.00 106.11 ? 412 TYR B CE1 1 
ATOM   4704 C CE2 . TYR B 1 412 ? 125.577 161.378 159.892 1.00 102.80 ? 412 TYR B CE2 1 
ATOM   4705 C CZ  . TYR B 1 412 ? 124.770 161.300 161.006 1.00 106.06 ? 412 TYR B CZ  1 
ATOM   4706 O OH  . TYR B 1 412 ? 125.310 160.943 162.220 1.00 106.60 ? 412 TYR B OH  1 
ATOM   4707 N N   . MET B 1 413 ? 125.018 164.867 156.724 1.00 105.13 ? 413 MET B N   1 
ATOM   4708 C CA  . MET B 1 413 ? 126.198 165.652 157.067 1.00 107.65 ? 413 MET B CA  1 
ATOM   4709 C C   . MET B 1 413 ? 125.829 167.108 157.305 1.00 114.10 ? 413 MET B C   1 
ATOM   4710 O O   . MET B 1 413 ? 126.356 167.755 158.215 1.00 117.49 ? 413 MET B O   1 
ATOM   4711 C CB  . MET B 1 413 ? 127.250 165.535 155.961 1.00 106.93 ? 413 MET B CB  1 
ATOM   4712 C CG  . MET B 1 413 ? 128.504 166.357 156.220 1.00 109.28 ? 413 MET B CG  1 
ATOM   4713 S SD  . MET B 1 413 ? 129.952 165.775 155.318 1.00 105.89 ? 413 MET B SD  1 
ATOM   4714 C CE  . MET B 1 413 ? 129.372 165.881 153.630 1.00 99.10  ? 413 MET B CE  1 
ATOM   4715 N N   . ILE B 1 414 ? 124.924 167.642 156.483 1.00 109.93 ? 414 ILE B N   1 
ATOM   4716 C CA  . ILE B 1 414 ? 124.453 169.009 156.688 1.00 108.53 ? 414 ILE B CA  1 
ATOM   4717 C C   . ILE B 1 414 ? 123.850 169.150 158.078 1.00 115.04 ? 414 ILE B C   1 
ATOM   4718 O O   . ILE B 1 414 ? 124.204 170.057 158.842 1.00 118.62 ? 414 ILE B O   1 
ATOM   4719 C CB  . ILE B 1 414 ? 123.443 169.400 155.596 1.00 104.57 ? 414 ILE B CB  1 
ATOM   4720 C CG1 . ILE B 1 414 ? 124.129 169.483 154.232 1.00 102.58 ? 414 ILE B CG1 1 
ATOM   4721 C CG2 . ILE B 1 414 ? 122.770 170.716 155.943 1.00 112.60 ? 414 ILE B CG2 1 
ATOM   4722 C CD1 . ILE B 1 414 ? 125.237 170.504 154.167 1.00 104.07 ? 414 ILE B CD1 1 
ATOM   4723 N N   . CYS B 1 415 ? 122.952 168.232 158.437 1.00 115.92 ? 415 CYS B N   1 
ATOM   4724 C CA  . CYS B 1 415 ? 122.320 168.291 159.753 1.00 119.31 ? 415 CYS B CA  1 
ATOM   4725 C C   . CYS B 1 415 ? 123.342 168.119 160.872 1.00 123.29 ? 415 CYS B C   1 
ATOM   4726 O O   . CYS B 1 415 ? 123.285 168.820 161.889 1.00 127.92 ? 415 CYS B O   1 
ATOM   4727 C CB  . CYS B 1 415 ? 121.227 167.229 159.860 1.00 116.75 ? 415 CYS B CB  1 
ATOM   4728 S SG  . CYS B 1 415 ? 119.817 167.499 158.769 1.00 133.44 ? 415 CYS B SG  1 
ATOM   4729 N N   . PHE B 1 416 ? 124.290 167.197 160.697 1.00 120.37 ? 416 PHE B N   1 
ATOM   4730 C CA  . PHE B 1 416 ? 125.227 166.864 161.764 1.00 121.76 ? 416 PHE B CA  1 
ATOM   4731 C C   . PHE B 1 416 ? 126.214 167.995 162.016 1.00 122.26 ? 416 PHE B C   1 
ATOM   4732 O O   . PHE B 1 416 ? 126.482 168.344 163.170 1.00 126.89 ? 416 PHE B O   1 
ATOM   4733 C CB  . PHE B 1 416 ? 125.958 165.567 161.417 1.00 120.14 ? 416 PHE B CB  1 
ATOM   4734 C CG  . PHE B 1 416 ? 127.045 165.198 162.385 1.00 124.18 ? 416 PHE B CG  1 
ATOM   4735 C CD1 . PHE B 1 416 ? 126.737 164.715 163.645 1.00 128.17 ? 416 PHE B CD1 1 
ATOM   4736 C CD2 . PHE B 1 416 ? 128.376 165.313 162.026 1.00 120.03 ? 416 PHE B CD2 1 
ATOM   4737 C CE1 . PHE B 1 416 ? 127.738 164.368 164.533 1.00 128.15 ? 416 PHE B CE1 1 
ATOM   4738 C CE2 . PHE B 1 416 ? 129.380 164.967 162.909 1.00 121.83 ? 416 PHE B CE2 1 
ATOM   4739 C CZ  . PHE B 1 416 ? 129.060 164.494 164.164 1.00 124.24 ? 416 PHE B CZ  1 
ATOM   4740 N N   . TYR B 1 417 ? 126.770 168.579 160.955 1.00 119.13 ? 417 TYR B N   1 
ATOM   4741 C CA  . TYR B 1 417 ? 127.682 169.701 161.133 1.00 119.07 ? 417 TYR B CA  1 
ATOM   4742 C C   . TYR B 1 417 ? 126.946 170.987 161.474 1.00 122.11 ? 417 TYR B C   1 
ATOM   4743 O O   . TYR B 1 417 ? 127.557 171.920 162.008 1.00 124.24 ? 417 TYR B O   1 
ATOM   4744 C CB  . TYR B 1 417 ? 128.529 169.903 159.877 1.00 116.19 ? 417 TYR B CB  1 
ATOM   4745 C CG  . TYR B 1 417 ? 129.701 168.958 159.772 1.00 113.93 ? 417 TYR B CG  1 
ATOM   4746 C CD1 . TYR B 1 417 ? 130.223 168.344 160.901 1.00 115.20 ? 417 TYR B CD1 1 
ATOM   4747 C CD2 . TYR B 1 417 ? 130.288 168.682 158.546 1.00 110.69 ? 417 TYR B CD2 1 
ATOM   4748 C CE1 . TYR B 1 417 ? 131.292 167.482 160.812 1.00 114.57 ? 417 TYR B CE1 1 
ATOM   4749 C CE2 . TYR B 1 417 ? 131.358 167.821 158.447 1.00 109.75 ? 417 TYR B CE2 1 
ATOM   4750 C CZ  . TYR B 1 417 ? 131.856 167.224 159.583 1.00 111.66 ? 417 TYR B CZ  1 
ATOM   4751 O OH  . TYR B 1 417 ? 132.923 166.364 159.492 1.00 114.50 ? 417 TYR B OH  1 
ATOM   4752 N N   . SER B 1 418 ? 125.649 171.064 161.181 1.00 123.67 ? 418 SER B N   1 
ATOM   4753 C CA  . SER B 1 418 ? 124.903 172.283 161.455 1.00 127.23 ? 418 SER B CA  1 
ATOM   4754 C C   . SER B 1 418 ? 124.154 172.243 162.781 1.00 129.45 ? 418 SER B C   1 
ATOM   4755 O O   . SER B 1 418 ? 124.098 173.263 163.477 1.00 132.99 ? 418 SER B O   1 
ATOM   4756 C CB  . SER B 1 418 ? 123.919 172.562 160.317 1.00 126.55 ? 418 SER B CB  1 
ATOM   4757 O OG  . SER B 1 418 ? 123.035 171.471 160.132 1.00 124.57 ? 418 SER B OG  1 
ATOM   4758 N N   . LEU B 1 419 ? 123.577 171.101 163.150 1.00 128.59 ? 419 LEU B N   1 
ATOM   4759 C CA  . LEU B 1 419 ? 122.736 171.022 164.338 1.00 131.14 ? 419 LEU B CA  1 
ATOM   4760 C C   . LEU B 1 419 ? 123.248 170.034 165.372 1.00 131.52 ? 419 LEU B C   1 
ATOM   4761 O O   . LEU B 1 419 ? 123.333 170.377 166.557 1.00 133.58 ? 419 LEU B O   1 
ATOM   4762 C CB  . LEU B 1 419 ? 121.298 170.655 163.935 1.00 133.50 ? 419 LEU B CB  1 
ATOM   4763 C CG  . LEU B 1 419 ? 120.627 171.600 162.937 1.00 134.29 ? 419 LEU B CG  1 
ATOM   4764 C CD1 . LEU B 1 419 ? 119.215 171.136 162.623 1.00 131.46 ? 419 LEU B CD1 1 
ATOM   4765 C CD2 . LEU B 1 419 ? 120.624 173.026 163.466 1.00 132.77 ? 419 LEU B CD2 1 
ATOM   4766 N N   . GLU B 1 420 ? 123.586 168.813 164.965 1.00 133.30 ? 420 GLU B N   1 
ATOM   4767 C CA  . GLU B 1 420 ? 123.974 167.788 165.925 1.00 136.34 ? 420 GLU B CA  1 
ATOM   4768 C C   . GLU B 1 420 ? 125.305 168.126 166.584 1.00 139.03 ? 420 GLU B C   1 
ATOM   4769 O O   . GLU B 1 420 ? 126.263 168.529 165.918 1.00 140.03 ? 420 GLU B O   1 
ATOM   4770 C CB  . GLU B 1 420 ? 124.062 166.423 165.244 1.00 132.67 ? 420 GLU B CB  1 
ATOM   4771 C CG  . GLU B 1 420 ? 122.785 165.597 165.312 1.00 135.78 ? 420 GLU B CG  1 
ATOM   4772 C CD  . GLU B 1 420 ? 121.666 166.165 164.463 1.00 139.70 ? 420 GLU B CD  1 
ATOM   4773 O OE1 . GLU B 1 420 ? 121.963 166.902 163.500 1.00 138.87 ? 420 GLU B OE1 1 
ATOM   4774 O OE2 . GLU B 1 420 ? 120.488 165.874 164.758 1.00 142.44 ? 420 GLU B OE2 1 
ATOM   4775 N N   . LEU B 1 421 ? 125.354 167.956 167.906 1.00 139.79 ? 421 LEU B N   1 
ATOM   4776 C CA  . LEU B 1 421 ? 126.565 168.150 168.697 1.00 141.04 ? 421 LEU B CA  1 
ATOM   4777 C C   . LEU B 1 421 ? 127.175 169.530 168.475 1.00 141.09 ? 421 LEU B C   1 
ATOM   4778 O O   . LEU B 1 421 ? 126.452 170.525 168.363 1.00 141.54 ? 421 LEU B O   1 
ATOM   4779 C CB  . LEU B 1 421 ? 127.586 167.056 168.376 1.00 142.60 ? 421 LEU B CB  1 
ATOM   4780 C CG  . LEU B 1 421 ? 127.083 165.624 168.565 1.00 139.76 ? 421 LEU B CG  1 
ATOM   4781 C CD1 . LEU B 1 421 ? 128.135 164.615 168.136 1.00 138.63 ? 421 LEU B CD1 1 
ATOM   4782 C CD2 . LEU B 1 421 ? 126.671 165.390 170.009 1.00 136.71 ? 421 LEU B CD2 1 
ATOM   4783 N N   . LYS B 1 422 ? 128.503 169.596 168.410 1.00 140.20 ? 422 LYS B N   1 
ATOM   4784 C CA  . LYS B 1 422 ? 129.199 170.858 168.205 1.00 140.91 ? 422 LYS B CA  1 
ATOM   4785 C C   . LYS B 1 422 ? 130.546 170.573 167.558 1.00 140.69 ? 422 LYS B C   1 
ATOM   4786 O O   . LYS B 1 422 ? 131.187 169.565 167.866 1.00 142.45 ? 422 LYS B O   1 
ATOM   4787 C CB  . LYS B 1 422 ? 129.387 171.615 169.527 1.00 140.34 ? 422 LYS B CB  1 
ATOM   4788 C CG  . LYS B 1 422 ? 129.924 173.030 169.366 1.00 139.91 ? 422 LYS B CG  1 
ATOM   4789 C CD  . LYS B 1 422 ? 129.021 173.860 168.467 1.00 139.80 ? 422 LYS B CD  1 
ATOM   4790 C CE  . LYS B 1 422 ? 129.559 175.269 168.280 1.00 139.67 ? 422 LYS B CE  1 
ATOM   4791 N NZ  . LYS B 1 422 ? 129.585 176.033 169.558 1.00 138.90 ? 422 LYS B NZ  1 
ATOM   4792 N N   . TRP B 1 423 ? 130.967 171.467 166.664 1.00 140.58 ? 423 TRP B N   1 
ATOM   4793 C CA  . TRP B 1 423 ? 132.235 171.310 165.965 1.00 138.81 ? 423 TRP B CA  1 
ATOM   4794 C C   . TRP B 1 423 ? 133.423 171.834 166.760 1.00 139.61 ? 423 TRP B C   1 
ATOM   4795 O O   . TRP B 1 423 ? 134.561 171.704 166.296 1.00 136.59 ? 423 TRP B O   1 
ATOM   4796 C CB  . TRP B 1 423 ? 132.176 172.006 164.601 1.00 133.31 ? 423 TRP B CB  1 
ATOM   4797 C CG  . TRP B 1 423 ? 131.620 173.391 164.652 1.00 138.30 ? 423 TRP B CG  1 
ATOM   4798 C CD1 . TRP B 1 423 ? 130.305 173.743 164.727 1.00 139.64 ? 423 TRP B CD1 1 
ATOM   4799 C CD2 . TRP B 1 423 ? 132.362 174.616 164.617 1.00 142.15 ? 423 TRP B CD2 1 
ATOM   4800 N NE1 . TRP B 1 423 ? 130.181 175.111 164.751 1.00 141.51 ? 423 TRP B NE1 1 
ATOM   4801 C CE2 . TRP B 1 423 ? 131.429 175.671 164.683 1.00 143.41 ? 423 TRP B CE2 1 
ATOM   4802 C CE3 . TRP B 1 423 ? 133.724 174.924 164.540 1.00 140.83 ? 423 TRP B CE3 1 
ATOM   4803 C CZ2 . TRP B 1 423 ? 131.813 177.010 164.674 1.00 140.64 ? 423 TRP B CZ2 1 
ATOM   4804 C CZ3 . TRP B 1 423 ? 134.103 176.255 164.531 1.00 139.05 ? 423 TRP B CZ3 1 
ATOM   4805 C CH2 . TRP B 1 423 ? 133.151 177.281 164.598 1.00 139.17 ? 423 TRP B CH2 1 
ATOM   4806 N N   . ASP B 1 424 ? 133.194 172.417 167.938 1.00 143.08 ? 424 ASP B N   1 
ATOM   4807 C CA  . ASP B 1 424 ? 134.303 172.865 168.770 1.00 144.10 ? 424 ASP B CA  1 
ATOM   4808 C C   . ASP B 1 424 ? 135.017 171.707 169.453 1.00 142.77 ? 424 ASP B C   1 
ATOM   4809 O O   . ASP B 1 424 ? 136.097 171.907 170.019 1.00 143.04 ? 424 ASP B O   1 
ATOM   4810 C CB  . ASP B 1 424 ? 133.810 173.861 169.821 1.00 144.53 ? 424 ASP B CB  1 
ATOM   4811 C CG  . ASP B 1 424 ? 133.279 175.143 169.209 1.00 143.16 ? 424 ASP B CG  1 
ATOM   4812 O OD1 . ASP B 1 424 ? 133.670 175.468 168.069 1.00 140.87 ? 424 ASP B OD1 1 
ATOM   4813 O OD2 . ASP B 1 424 ? 132.474 175.830 169.873 1.00 141.38 ? 424 ASP B OD2 1 
ATOM   4814 N N   . GLU B 1 425 ? 134.444 170.509 169.414 1.00 142.41 ? 425 GLU B N   1 
ATOM   4815 C CA  . GLU B 1 425 ? 135.027 169.349 170.067 1.00 144.58 ? 425 GLU B CA  1 
ATOM   4816 C C   . GLU B 1 425 ? 135.914 168.577 169.092 1.00 145.37 ? 425 GLU B C   1 
ATOM   4817 O O   . GLU B 1 425 ? 135.967 168.864 167.895 1.00 143.17 ? 425 GLU B O   1 
ATOM   4818 C CB  . GLU B 1 425 ? 133.926 168.449 170.627 1.00 144.81 ? 425 GLU B CB  1 
ATOM   4819 C CG  . GLU B 1 425 ? 132.783 169.216 171.270 1.00 142.29 ? 425 GLU B CG  1 
ATOM   4820 C CD  . GLU B 1 425 ? 131.682 168.308 171.778 1.00 139.51 ? 425 GLU B CD  1 
ATOM   4821 O OE1 . GLU B 1 425 ? 132.000 167.268 172.390 1.00 135.64 ? 425 GLU B OE1 1 
ATOM   4822 O OE2 . GLU B 1 425 ? 130.495 168.632 171.561 1.00 138.79 ? 425 GLU B OE2 1 
ATOM   4823 N N   . SER B 1 426 ? 136.622 167.586 169.624 1.00 147.22 ? 426 SER B N   1 
ATOM   4824 C CA  . SER B 1 426 ? 137.527 166.750 168.849 1.00 149.12 ? 426 SER B CA  1 
ATOM   4825 C C   . SER B 1 426 ? 137.038 165.304 168.849 1.00 150.60 ? 426 SER B C   1 
ATOM   4826 O O   . SER B 1 426 ? 136.098 164.939 169.561 1.00 152.54 ? 426 SER B O   1 
ATOM   4827 C CB  . SER B 1 426 ? 138.952 166.848 169.398 1.00 146.18 ? 426 SER B CB  1 
ATOM   4828 O OG  . SER B 1 426 ? 139.460 168.165 169.272 1.00 143.93 ? 426 SER B OG  1 
ATOM   4829 N N   . LYS B 1 427 ? 137.694 164.483 168.025 1.00 149.29 ? 427 LYS B N   1 
ATOM   4830 C CA  . LYS B 1 427 ? 137.397 163.060 167.885 1.00 151.12 ? 427 LYS B CA  1 
ATOM   4831 C C   . LYS B 1 427 ? 135.977 162.810 167.388 1.00 153.51 ? 427 LYS B C   1 
ATOM   4832 O O   . LYS B 1 427 ? 135.256 163.750 167.036 1.00 154.02 ? 427 LYS B O   1 
ATOM   4833 C CB  . LYS B 1 427 ? 137.629 162.328 169.211 1.00 151.24 ? 427 LYS B CB  1 
ATOM   4834 C CG  . LYS B 1 427 ? 139.072 162.347 169.686 1.00 152.44 ? 427 LYS B CG  1 
ATOM   4835 C CD  . LYS B 1 427 ? 139.253 161.491 170.928 1.00 152.63 ? 427 LYS B CD  1 
ATOM   4836 C CE  . LYS B 1 427 ? 140.702 161.473 171.383 1.00 147.50 ? 427 LYS B CE  1 
ATOM   4837 N NZ  . LYS B 1 427 ? 140.886 160.639 172.603 1.00 144.28 ? 427 LYS B NZ  1 
ATOM   4838 N N   . GLY B 1 428 ? 135.573 161.542 167.345 1.00 153.72 ? 428 GLY B N   1 
ATOM   4839 C CA  . GLY B 1 428 ? 134.242 161.163 166.918 1.00 152.22 ? 428 GLY B CA  1 
ATOM   4840 C C   . GLY B 1 428 ? 133.171 161.261 167.977 1.00 153.46 ? 428 GLY B C   1 
ATOM   4841 O O   . GLY B 1 428 ? 131.997 161.024 167.677 1.00 153.14 ? 428 GLY B O   1 
ATOM   4842 N N   . LEU B 1 429 ? 133.552 161.589 169.214 1.00 155.02 ? 429 LEU B N   1 
ATOM   4843 C CA  . LEU B 1 429 ? 132.624 161.806 170.320 1.00 153.05 ? 429 LEU B CA  1 
ATOM   4844 C C   . LEU B 1 429 ? 131.836 160.550 170.674 1.00 149.93 ? 429 LEU B C   1 
ATOM   4845 O O   . LEU B 1 429 ? 132.069 159.477 170.108 1.00 149.47 ? 429 LEU B O   1 
ATOM   4846 C CB  . LEU B 1 429 ? 131.670 162.961 170.002 1.00 151.93 ? 429 LEU B CB  1 
ATOM   4847 C CG  . LEU B 1 429 ? 132.348 164.323 169.838 1.00 150.66 ? 429 LEU B CG  1 
ATOM   4848 C CD1 . LEU B 1 429 ? 131.322 165.428 169.652 1.00 145.32 ? 429 LEU B CD1 1 
ATOM   4849 C CD2 . LEU B 1 429 ? 133.245 164.614 171.032 1.00 149.21 ? 429 LEU B CD2 1 
ATOM   4850 N N   . LEU B 1 430 ? 130.911 160.680 171.623 1.00 150.56 ? 430 LEU B N   1 
ATOM   4851 C CA  . LEU B 1 430 ? 130.137 159.541 172.085 1.00 153.21 ? 430 LEU B CA  1 
ATOM   4852 C C   . LEU B 1 430 ? 129.185 159.055 170.993 1.00 153.38 ? 430 LEU B C   1 
ATOM   4853 O O   . LEU B 1 430 ? 128.689 159.849 170.190 1.00 153.93 ? 430 LEU B O   1 
ATOM   4854 C CB  . LEU B 1 430 ? 129.340 159.907 173.335 1.00 153.46 ? 430 LEU B CB  1 
ATOM   4855 C CG  . LEU B 1 430 ? 130.145 160.262 174.584 1.00 153.24 ? 430 LEU B CG  1 
ATOM   4856 C CD1 . LEU B 1 430 ? 129.216 160.630 175.729 1.00 149.09 ? 430 LEU B CD1 1 
ATOM   4857 C CD2 . LEU B 1 430 ? 131.053 159.109 174.976 1.00 153.53 ? 430 LEU B CD2 1 
ATOM   4858 N N   . PRO B 1 431 ? 128.916 157.741 170.940 1.00 153.61 ? 431 PRO B N   1 
ATOM   4859 C CA  . PRO B 1 431 ? 127.978 157.149 169.980 1.00 153.65 ? 431 PRO B CA  1 
ATOM   4860 C C   . PRO B 1 431 ? 126.563 157.705 170.113 1.00 157.08 ? 431 PRO B C   1 
ATOM   4861 O O   . PRO B 1 431 ? 125.622 156.917 170.193 1.00 158.96 ? 431 PRO B O   1 
ATOM   4862 C CB  . PRO B 1 431 ? 128.008 155.660 170.335 1.00 153.97 ? 431 PRO B CB  1 
ATOM   4863 C CG  . PRO B 1 431 ? 129.332 155.455 170.984 1.00 151.57 ? 431 PRO B CG  1 
ATOM   4864 C CD  . PRO B 1 431 ? 129.595 156.715 171.749 1.00 152.28 ? 431 PRO B CD  1 
ATOM   4865 N N   . GLY B 1 446 ? 109.989 164.286 158.662 1.00 104.86 ? 446 GLY B N   1 
ATOM   4866 C CA  . GLY B 1 446 ? 109.809 164.746 157.297 1.00 103.52 ? 446 GLY B CA  1 
ATOM   4867 C C   . GLY B 1 446 ? 111.112 165.173 156.651 1.00 104.09 ? 446 GLY B C   1 
ATOM   4868 O O   . GLY B 1 446 ? 112.172 164.643 156.983 1.00 106.01 ? 446 GLY B O   1 
ATOM   4869 N N   . VAL B 1 447 ? 111.025 166.126 155.721 1.00 99.22  ? 447 VAL B N   1 
ATOM   4870 C CA  . VAL B 1 447 ? 112.189 166.673 155.030 1.00 100.11 ? 447 VAL B CA  1 
ATOM   4871 C C   . VAL B 1 447 ? 112.952 165.561 154.322 1.00 100.71 ? 447 VAL B C   1 
ATOM   4872 O O   . VAL B 1 447 ? 112.883 165.432 153.095 1.00 99.73  ? 447 VAL B O   1 
ATOM   4873 C CB  . VAL B 1 447 ? 113.112 167.437 155.996 1.00 99.31  ? 447 VAL B CB  1 
ATOM   4874 C CG1 . VAL B 1 447 ? 114.316 167.986 155.246 1.00 97.14  ? 447 VAL B CG1 1 
ATOM   4875 C CG2 . VAL B 1 447 ? 112.350 168.556 156.678 1.00 100.88 ? 447 VAL B CG2 1 
ATOM   4876 N N   . ARG B 1 448 ? 113.687 164.762 155.097 1.00 101.71 ? 448 ARG B N   1 
ATOM   4877 C CA  . ARG B 1 448 ? 114.540 163.693 154.590 1.00 99.00  ? 448 ARG B CA  1 
ATOM   4878 C C   . ARG B 1 448 ? 113.840 162.827 153.548 1.00 96.56  ? 448 ARG B C   1 
ATOM   4879 O O   . ARG B 1 448 ? 114.452 162.433 152.551 1.00 95.43  ? 448 ARG B O   1 
ATOM   4880 C CB  . ARG B 1 448 ? 115.031 162.834 155.757 1.00 101.78 ? 448 ARG B CB  1 
ATOM   4881 C CG  . ARG B 1 448 ? 115.260 161.373 155.422 1.00 106.85 ? 448 ARG B CG  1 
ATOM   4882 C CD  . ARG B 1 448 ? 116.080 160.675 156.500 1.00 108.66 ? 448 ARG B CD  1 
ATOM   4883 N NE  . ARG B 1 448 ? 117.498 161.002 156.412 1.00 109.32 ? 448 ARG B NE  1 
ATOM   4884 C CZ  . ARG B 1 448 ? 118.108 161.916 157.155 1.00 110.98 ? 448 ARG B CZ  1 
ATOM   4885 N NH1 . ARG B 1 448 ? 117.454 162.610 158.073 1.00 107.03 ? 448 ARG B NH1 1 
ATOM   4886 N NH2 . ARG B 1 448 ? 119.406 162.140 156.972 1.00 112.24 ? 448 ARG B NH2 1 
ATOM   4887 N N   . ALA B 1 449 ? 112.561 162.534 153.759 1.00 94.95  ? 449 ALA B N   1 
ATOM   4888 C CA  . ALA B 1 449 ? 111.796 161.776 152.779 1.00 93.21  ? 449 ALA B CA  1 
ATOM   4889 C C   . ALA B 1 449 ? 111.719 162.538 151.464 1.00 91.35  ? 449 ALA B C   1 
ATOM   4890 O O   . ALA B 1 449 ? 111.855 161.952 150.383 1.00 89.99  ? 449 ALA B O   1 
ATOM   4891 C CB  . ALA B 1 449 ? 110.394 161.480 153.309 1.00 95.25  ? 449 ALA B CB  1 
ATOM   4892 N N   . ILE B 1 450 ? 111.506 163.852 151.550 1.00 92.54  ? 450 ILE B N   1 
ATOM   4893 C CA  . ILE B 1 450 ? 111.344 164.656 150.345 1.00 94.19  ? 450 ILE B CA  1 
ATOM   4894 C C   . ILE B 1 450 ? 112.632 164.681 149.532 1.00 94.37  ? 450 ILE B C   1 
ATOM   4895 O O   . ILE B 1 450 ? 112.608 164.519 148.307 1.00 93.16  ? 450 ILE B O   1 
ATOM   4896 C CB  . ILE B 1 450 ? 110.877 166.073 150.711 1.00 96.60  ? 450 ILE B CB  1 
ATOM   4897 C CG1 . ILE B 1 450 ? 109.651 166.005 151.622 1.00 99.02  ? 450 ILE B CG1 1 
ATOM   4898 C CG2 . ILE B 1 450 ? 110.569 166.860 149.456 1.00 99.47  ? 450 ILE B CG2 1 
ATOM   4899 C CD1 . ILE B 1 450 ? 108.476 165.275 151.012 1.00 94.83  ? 450 ILE B CD1 1 
ATOM   4900 N N   . VAL B 1 451 ? 113.774 164.887 150.190 1.00 95.98  ? 451 VAL B N   1 
ATOM   4901 C CA  . VAL B 1 451 ? 115.047 164.915 149.471 1.00 94.33  ? 451 VAL B CA  1 
ATOM   4902 C C   . VAL B 1 451 ? 115.403 163.520 148.970 1.00 91.50  ? 451 VAL B C   1 
ATOM   4903 O O   . VAL B 1 451 ? 116.056 163.360 147.934 1.00 87.84  ? 451 VAL B O   1 
ATOM   4904 C CB  . VAL B 1 451 ? 116.163 165.508 150.351 1.00 97.59  ? 451 VAL B CB  1 
ATOM   4905 C CG1 . VAL B 1 451 ? 116.435 164.632 151.556 1.00 99.12  ? 451 VAL B CG1 1 
ATOM   4906 C CG2 . VAL B 1 451 ? 117.433 165.703 149.537 1.00 99.67  ? 451 VAL B CG2 1 
ATOM   4907 N N   . GLN B 1 452 ? 114.973 162.491 149.698 1.00 90.18  ? 452 GLN B N   1 
ATOM   4908 C CA  . GLN B 1 452 ? 115.172 161.116 149.265 1.00 87.28  ? 452 GLN B CA  1 
ATOM   4909 C C   . GLN B 1 452 ? 114.429 160.859 147.963 1.00 83.75  ? 452 GLN B C   1 
ATOM   4910 O O   . GLN B 1 452 ? 114.933 160.159 147.081 1.00 76.88  ? 452 GLN B O   1 
ATOM   4911 C CB  . GLN B 1 452 ? 114.703 160.142 150.346 1.00 87.31  ? 452 GLN B CB  1 
ATOM   4912 C CG  . GLN B 1 452 ? 115.127 158.703 150.118 1.00 88.81  ? 452 GLN B CG  1 
ATOM   4913 C CD  . GLN B 1 452 ? 114.173 157.946 149.223 1.00 97.29  ? 452 GLN B CD  1 
ATOM   4914 O OE1 . GLN B 1 452 ? 113.174 157.404 149.688 1.00 101.53 ? 452 GLN B OE1 1 
ATOM   4915 N NE2 . GLN B 1 452 ? 114.479 157.896 147.933 1.00 98.07  ? 452 GLN B NE2 1 
ATOM   4916 N N   . CYS B 1 453 ? 113.225 161.404 147.841 1.00 84.87  ? 453 CYS B N   1 
ATOM   4917 C CA  . CYS B 1 453 ? 112.421 161.186 146.645 1.00 80.10  ? 453 CYS B CA  1 
ATOM   4918 C C   . CYS B 1 453 ? 112.893 161.993 145.442 1.00 77.67  ? 453 CYS B C   1 
ATOM   4919 O O   . CYS B 1 453 ? 112.331 161.824 144.356 1.00 77.33  ? 453 CYS B O   1 
ATOM   4920 C CB  . CYS B 1 453 ? 110.955 161.507 146.932 1.00 83.63  ? 453 CYS B CB  1 
ATOM   4921 S SG  . CYS B 1 453 ? 110.186 160.421 148.148 1.00 96.50  ? 453 CYS B SG  1 
ATOM   4922 N N   . ILE B 1 454 ? 113.889 162.861 145.600 1.00 73.66  ? 454 ILE B N   1 
ATOM   4923 C CA  . ILE B 1 454 ? 114.369 163.713 144.511 1.00 71.03  ? 454 ILE B CA  1 
ATOM   4924 C C   . ILE B 1 454 ? 114.865 162.892 143.322 1.00 68.35  ? 454 ILE B C   1 
ATOM   4925 O O   . ILE B 1 454 ? 114.507 163.213 142.179 1.00 65.05  ? 454 ILE B O   1 
ATOM   4926 C CB  . ILE B 1 454 ? 115.459 164.679 145.004 1.00 72.87  ? 454 ILE B CB  1 
ATOM   4927 C CG1 . ILE B 1 454 ? 114.851 165.725 145.935 1.00 78.86  ? 454 ILE B CG1 1 
ATOM   4928 C CG2 . ILE B 1 454 ? 116.152 165.343 143.831 1.00 74.15  ? 454 ILE B CG2 1 
ATOM   4929 C CD1 . ILE B 1 454 ? 115.831 166.773 146.395 1.00 85.47  ? 454 ILE B CD1 1 
ATOM   4930 N N   . PRO B 1 455 ? 115.685 161.849 143.507 1.00 72.24  ? 455 PRO B N   1 
ATOM   4931 C CA  . PRO B 1 455 ? 116.056 161.011 142.355 1.00 69.15  ? 455 PRO B CA  1 
ATOM   4932 C C   . PRO B 1 455 ? 114.874 160.346 141.680 1.00 68.53  ? 455 PRO B C   1 
ATOM   4933 O O   . PRO B 1 455 ? 114.954 160.056 140.480 1.00 70.12  ? 455 PRO B O   1 
ATOM   4934 C CB  . PRO B 1 455 ? 116.996 159.970 142.968 1.00 65.46  ? 455 PRO B CB  1 
ATOM   4935 C CG  . PRO B 1 455 ? 117.553 160.634 144.152 1.00 67.59  ? 455 PRO B CG  1 
ATOM   4936 C CD  . PRO B 1 455 ? 116.438 161.448 144.708 1.00 73.24  ? 455 PRO B CD  1 
ATOM   4937 N N   . ALA B 1 456 ? 113.793 160.079 142.410 1.00 67.25  ? 456 ALA B N   1 
ATOM   4938 C CA  . ALA B 1 456 ? 112.564 159.586 141.817 1.00 61.00  ? 456 ALA B CA  1 
ATOM   4939 C C   . ALA B 1 456 ? 111.651 160.698 141.337 1.00 64.04  ? 456 ALA B C   1 
ATOM   4940 O O   . ALA B 1 456 ? 110.886 160.477 140.396 1.00 66.47  ? 456 ALA B O   1 
ATOM   4941 C CB  . ALA B 1 456 ? 111.796 158.704 142.810 1.00 68.99  ? 456 ALA B CB  1 
ATOM   4942 N N   . TRP B 1 457 ? 111.710 161.882 141.941 1.00 67.48  ? 457 TRP B N   1 
ATOM   4943 C CA  . TRP B 1 457 ? 110.955 163.017 141.432 1.00 67.51  ? 457 TRP B CA  1 
ATOM   4944 C C   . TRP B 1 457 ? 111.463 163.501 140.083 1.00 69.52  ? 457 TRP B C   1 
ATOM   4945 O O   . TRP B 1 457 ? 110.649 163.839 139.222 1.00 70.37  ? 457 TRP B O   1 
ATOM   4946 C CB  . TRP B 1 457 ? 110.982 164.168 142.437 1.00 63.54  ? 457 TRP B CB  1 
ATOM   4947 C CG  . TRP B 1 457 ? 110.071 165.289 142.065 1.00 64.10  ? 457 TRP B CG  1 
ATOM   4948 C CD1 . TRP B 1 457 ? 108.737 165.381 142.327 1.00 69.05  ? 457 TRP B CD1 1 
ATOM   4949 C CD2 . TRP B 1 457 ? 110.423 166.479 141.358 1.00 65.07  ? 457 TRP B CD2 1 
ATOM   4950 N NE1 . TRP B 1 457 ? 108.236 166.556 141.829 1.00 67.01  ? 457 TRP B NE1 1 
ATOM   4951 C CE2 . TRP B 1 457 ? 109.253 167.250 141.229 1.00 67.15  ? 457 TRP B CE2 1 
ATOM   4952 C CE3 . TRP B 1 457 ? 111.615 166.970 140.824 1.00 68.38  ? 457 TRP B CE3 1 
ATOM   4953 C CZ2 . TRP B 1 457 ? 109.241 168.483 140.588 1.00 70.69  ? 457 TRP B CZ2 1 
ATOM   4954 C CZ3 . TRP B 1 457 ? 111.602 168.194 140.188 1.00 73.45  ? 457 TRP B CZ3 1 
ATOM   4955 C CH2 . TRP B 1 457 ? 110.423 168.938 140.074 1.00 77.54  ? 457 TRP B CH2 1 
ATOM   4956 N N   . LEU B 1 458 ? 112.780 163.531 139.872 1.00 71.98  ? 458 LEU B N   1 
ATOM   4957 C CA  . LEU B 1 458 ? 113.349 163.909 138.587 1.00 67.33  ? 458 LEU B CA  1 
ATOM   4958 C C   . LEU B 1 458 ? 113.103 162.891 137.491 1.00 62.07  ? 458 LEU B C   1 
ATOM   4959 O O   . LEU B 1 458 ? 113.272 163.225 136.315 1.00 61.55  ? 458 LEU B O   1 
ATOM   4960 C CB  . LEU B 1 458 ? 114.862 164.138 138.714 1.00 58.79  ? 458 LEU B CB  1 
ATOM   4961 C CG  . LEU B 1 458 ? 115.266 165.197 139.736 1.00 62.36  ? 458 LEU B CG  1 
ATOM   4962 C CD1 . LEU B 1 458 ? 116.764 165.193 139.942 1.00 69.03  ? 458 LEU B CD1 1 
ATOM   4963 C CD2 . LEU B 1 458 ? 114.788 166.566 139.289 1.00 67.44  ? 458 LEU B CD2 1 
ATOM   4964 N N   . ARG B 1 459 ? 112.722 161.666 137.837 1.00 60.72  ? 459 ARG B N   1 
ATOM   4965 C CA  . ARG B 1 459 ? 112.324 160.669 136.859 1.00 58.10  ? 459 ARG B CA  1 
ATOM   4966 C C   . ARG B 1 459 ? 110.818 160.603 136.677 1.00 61.23  ? 459 ARG B C   1 
ATOM   4967 O O   . ARG B 1 459 ? 110.356 160.212 135.602 1.00 65.32  ? 459 ARG B O   1 
ATOM   4968 C CB  . ARG B 1 459 ? 112.852 159.290 137.263 1.00 54.75  ? 459 ARG B CB  1 
ATOM   4969 C CG  . ARG B 1 459 ? 114.279 159.025 136.843 1.00 52.95  ? 459 ARG B CG  1 
ATOM   4970 C CD  . ARG B 1 459 ? 114.316 158.280 135.526 1.00 54.60  ? 459 ARG B CD  1 
ATOM   4971 N NE  . ARG B 1 459 ? 113.767 159.060 134.426 1.00 51.91  ? 459 ARG B NE  1 
ATOM   4972 C CZ  . ARG B 1 459 ? 113.207 158.534 133.348 1.00 53.20  ? 459 ARG B CZ  1 
ATOM   4973 N NH1 . ARG B 1 459 ? 113.065 157.228 133.211 1.00 58.06  ? 459 ARG B NH1 1 
ATOM   4974 N NH2 . ARG B 1 459 ? 112.768 159.340 132.387 1.00 54.48  ? 459 ARG B NH2 1 
ATOM   4975 N N   . PHE B 1 460 ? 110.047 160.966 137.699 1.00 60.13  ? 460 PHE B N   1 
ATOM   4976 C CA  . PHE B 1 460 ? 108.608 161.093 137.529 1.00 63.26  ? 460 PHE B CA  1 
ATOM   4977 C C   . PHE B 1 460 ? 108.260 162.321 136.704 1.00 67.30  ? 460 PHE B C   1 
ATOM   4978 O O   . PHE B 1 460 ? 107.300 162.296 135.930 1.00 69.52  ? 460 PHE B O   1 
ATOM   4979 C CB  . PHE B 1 460 ? 107.919 161.151 138.890 1.00 63.28  ? 460 PHE B CB  1 
ATOM   4980 C CG  . PHE B 1 460 ? 106.468 161.523 138.817 1.00 65.15  ? 460 PHE B CG  1 
ATOM   4981 C CD1 . PHE B 1 460 ? 105.587 160.783 138.050 1.00 67.54  ? 460 PHE B CD1 1 
ATOM   4982 C CD2 . PHE B 1 460 ? 105.982 162.608 139.523 1.00 63.56  ? 460 PHE B CD2 1 
ATOM   4983 C CE1 . PHE B 1 460 ? 104.253 161.124 137.984 1.00 66.01  ? 460 PHE B CE1 1 
ATOM   4984 C CE2 . PHE B 1 460 ? 104.649 162.949 139.465 1.00 64.90  ? 460 PHE B CE2 1 
ATOM   4985 C CZ  . PHE B 1 460 ? 103.783 162.206 138.693 1.00 65.32  ? 460 PHE B CZ  1 
ATOM   4986 N N   . ILE B 1 461 ? 109.026 163.404 136.856 1.00 67.94  ? 461 ILE B N   1 
ATOM   4987 C CA  . ILE B 1 461 ? 108.778 164.589 136.043 1.00 68.76  ? 461 ILE B CA  1 
ATOM   4988 C C   . ILE B 1 461 ? 109.084 164.312 134.580 1.00 71.92  ? 461 ILE B C   1 
ATOM   4989 O O   . ILE B 1 461 ? 108.343 164.746 133.691 1.00 73.50  ? 461 ILE B O   1 
ATOM   4990 C CB  . ILE B 1 461 ? 109.580 165.785 136.570 1.00 67.69  ? 461 ILE B CB  1 
ATOM   4991 C CG1 . ILE B 1 461 ? 109.100 166.158 137.969 1.00 66.02  ? 461 ILE B CG1 1 
ATOM   4992 C CG2 . ILE B 1 461 ? 109.410 166.957 135.650 1.00 70.47  ? 461 ILE B CG2 1 
ATOM   4993 C CD1 . ILE B 1 461 ? 107.613 166.378 138.061 1.00 67.72  ? 461 ILE B CD1 1 
ATOM   4994 N N   . GLN B 1 462 ? 110.169 163.602 134.299 1.00 70.00  ? 462 GLN B N   1 
ATOM   4995 C CA  . GLN B 1 462 ? 110.372 163.055 132.967 1.00 69.00  ? 462 GLN B CA  1 
ATOM   4996 C C   . GLN B 1 462 ? 109.350 161.940 132.760 1.00 71.47  ? 462 GLN B C   1 
ATOM   4997 O O   . GLN B 1 462 ? 108.760 161.426 133.713 1.00 67.90  ? 462 GLN B O   1 
ATOM   4998 C CB  . GLN B 1 462 ? 111.810 162.582 132.793 1.00 62.85  ? 462 GLN B CB  1 
ATOM   4999 C CG  . GLN B 1 462 ? 112.846 163.652 133.062 1.00 58.09  ? 462 GLN B CG  1 
ATOM   5000 C CD  . GLN B 1 462 ? 114.256 163.142 132.898 1.00 53.00  ? 462 GLN B CD  1 
ATOM   5001 O OE1 . GLN B 1 462 ? 114.525 162.307 132.042 1.00 57.46  ? 462 GLN B OE1 1 
ATOM   5002 N NE2 . GLN B 1 462 ? 115.163 163.636 133.725 1.00 55.63  ? 462 GLN B NE2 1 
ATOM   5003 N N   . CYS B 1 463 ? 109.101 161.598 131.495 1.00 73.10  ? 463 CYS B N   1 
ATOM   5004 C CA  . CYS B 1 463 ? 108.028 160.703 131.066 1.00 79.62  ? 463 CYS B CA  1 
ATOM   5005 C C   . CYS B 1 463 ? 106.683 161.401 131.230 1.00 82.12  ? 463 CYS B C   1 
ATOM   5006 O O   . CYS B 1 463 ? 105.659 160.917 130.743 1.00 88.70  ? 463 CYS B O   1 
ATOM   5007 C CB  . CYS B 1 463 ? 108.054 159.372 131.826 1.00 80.56  ? 463 CYS B CB  1 
ATOM   5008 S SG  . CYS B 1 463 ? 109.515 158.360 131.510 1.00 100.84 ? 463 CYS B SG  1 
ATOM   5009 N N   . LEU B 1 464 ? 106.684 162.553 131.896 1.00 79.83  ? 464 LEU B N   1 
ATOM   5010 C CA  . LEU B 1 464 ? 105.578 163.487 131.754 1.00 81.14  ? 464 LEU B CA  1 
ATOM   5011 C C   . LEU B 1 464 ? 105.922 164.539 130.713 1.00 85.99  ? 464 LEU B C   1 
ATOM   5012 O O   . LEU B 1 464 ? 105.093 164.883 129.864 1.00 88.18  ? 464 LEU B O   1 
ATOM   5013 C CB  . LEU B 1 464 ? 105.250 164.135 133.100 1.00 77.00  ? 464 LEU B CB  1 
ATOM   5014 C CG  . LEU B 1 464 ? 104.843 163.176 134.220 1.00 69.43  ? 464 LEU B CG  1 
ATOM   5015 C CD1 . LEU B 1 464 ? 104.528 163.924 135.507 1.00 66.50  ? 464 LEU B CD1 1 
ATOM   5016 C CD2 . LEU B 1 464 ? 103.667 162.318 133.790 1.00 70.62  ? 464 LEU B CD2 1 
ATOM   5017 N N   . ARG B 1 465 ? 107.157 165.043 130.755 1.00 84.24  ? 465 ARG B N   1 
ATOM   5018 C CA  . ARG B 1 465 ? 107.667 165.864 129.666 1.00 85.12  ? 465 ARG B CA  1 
ATOM   5019 C C   . ARG B 1 465 ? 107.698 165.075 128.365 1.00 89.11  ? 465 ARG B C   1 
ATOM   5020 O O   . ARG B 1 465 ? 107.334 165.592 127.301 1.00 92.12  ? 465 ARG B O   1 
ATOM   5021 C CB  . ARG B 1 465 ? 109.060 166.376 130.026 1.00 78.17  ? 465 ARG B CB  1 
ATOM   5022 C CG  . ARG B 1 465 ? 109.771 167.126 128.924 1.00 81.85  ? 465 ARG B CG  1 
ATOM   5023 C CD  . ARG B 1 465 ? 109.177 168.498 128.722 1.00 83.09  ? 465 ARG B CD  1 
ATOM   5024 N NE  . ARG B 1 465 ? 110.201 169.488 128.412 1.00 82.54  ? 465 ARG B NE  1 
ATOM   5025 C CZ  . ARG B 1 465 ? 110.667 169.726 127.195 1.00 86.05  ? 465 ARG B CZ  1 
ATOM   5026 N NH1 . ARG B 1 465 ? 110.233 169.050 126.145 1.00 89.49  ? 465 ARG B NH1 1 
ATOM   5027 N NH2 . ARG B 1 465 ? 111.590 170.667 127.027 1.00 86.97  ? 465 ARG B NH2 1 
ATOM   5028 N N   . ARG B 1 466 ? 108.115 163.810 128.435 1.00 87.24  ? 466 ARG B N   1 
ATOM   5029 C CA  . ARG B 1 466 ? 108.124 162.966 127.247 1.00 86.18  ? 466 ARG B CA  1 
ATOM   5030 C C   . ARG B 1 466 ? 106.711 162.715 126.743 1.00 88.58  ? 466 ARG B C   1 
ATOM   5031 O O   . ARG B 1 466 ? 106.483 162.626 125.531 1.00 95.54  ? 466 ARG B O   1 
ATOM   5032 C CB  . ARG B 1 466 ? 108.838 161.649 127.546 1.00 86.39  ? 466 ARG B CB  1 
ATOM   5033 C CG  . ARG B 1 466 ? 110.270 161.829 128.027 1.00 84.68  ? 466 ARG B CG  1 
ATOM   5034 C CD  . ARG B 1 466 ? 111.007 160.505 128.126 1.00 82.08  ? 466 ARG B CD  1 
ATOM   5035 N NE  . ARG B 1 466 ? 110.896 159.729 126.897 1.00 79.38  ? 466 ARG B NE  1 
ATOM   5036 C CZ  . ARG B 1 466 ? 111.571 159.985 125.786 1.00 77.41  ? 466 ARG B CZ  1 
ATOM   5037 N NH1 . ARG B 1 466 ? 112.418 160.997 125.709 1.00 80.13  ? 466 ARG B NH1 1 
ATOM   5038 N NH2 . ARG B 1 466 ? 111.387 159.209 124.722 1.00 75.53  ? 466 ARG B NH2 1 
ATOM   5039 N N   . TYR B 1 467 ? 105.746 162.595 127.656 1.00 85.60  ? 467 TYR B N   1 
ATOM   5040 C CA  . TYR B 1 467 ? 104.359 162.459 127.228 1.00 90.48  ? 467 TYR B CA  1 
ATOM   5041 C C   . TYR B 1 467 ? 103.859 163.731 126.558 1.00 95.72  ? 467 TYR B C   1 
ATOM   5042 O O   . TYR B 1 467 ? 103.185 163.669 125.525 1.00 98.69  ? 467 TYR B O   1 
ATOM   5043 C CB  . TYR B 1 467 ? 103.466 162.100 128.411 1.00 91.13  ? 467 TYR B CB  1 
ATOM   5044 C CG  . TYR B 1 467 ? 101.999 162.125 128.062 1.00 95.01  ? 467 TYR B CG  1 
ATOM   5045 C CD1 . TYR B 1 467 ? 101.432 161.116 127.299 1.00 93.67  ? 467 TYR B CD1 1 
ATOM   5046 C CD2 . TYR B 1 467 ? 101.182 163.162 128.489 1.00 96.72  ? 467 TYR B CD2 1 
ATOM   5047 C CE1 . TYR B 1 467 ? 100.094 161.137 126.973 1.00 95.70  ? 467 TYR B CE1 1 
ATOM   5048 C CE2 . TYR B 1 467 ? 99.842  163.191 128.168 1.00 95.69  ? 467 TYR B CE2 1 
ATOM   5049 C CZ  . TYR B 1 467 ? 99.304  162.177 127.411 1.00 98.37  ? 467 TYR B CZ  1 
ATOM   5050 O OH  . TYR B 1 467 ? 97.967  162.204 127.091 1.00 100.98 ? 467 TYR B OH  1 
ATOM   5051 N N   . ARG B 1 468 ? 104.178 164.895 127.128 1.00 95.41  ? 468 ARG B N   1 
ATOM   5052 C CA  . ARG B 1 468 ? 103.751 166.152 126.523 1.00 95.57  ? 468 ARG B CA  1 
ATOM   5053 C C   . ARG B 1 468 ? 104.359 166.323 125.140 1.00 95.86  ? 468 ARG B C   1 
ATOM   5054 O O   . ARG B 1 468 ? 103.724 166.877 124.236 1.00 97.06  ? 468 ARG B O   1 
ATOM   5055 C CB  . ARG B 1 468 ? 104.131 167.329 127.422 1.00 90.15  ? 468 ARG B CB  1 
ATOM   5056 C CG  . ARG B 1 468 ? 103.468 167.316 128.788 1.00 89.71  ? 468 ARG B CG  1 
ATOM   5057 C CD  . ARG B 1 468 ? 104.123 168.315 129.730 1.00 91.40  ? 468 ARG B CD  1 
ATOM   5058 N NE  . ARG B 1 468 ? 103.606 168.200 131.089 1.00 94.42  ? 468 ARG B NE  1 
ATOM   5059 C CZ  . ARG B 1 468 ? 104.093 168.852 132.137 1.00 94.13  ? 468 ARG B CZ  1 
ATOM   5060 N NH1 . ARG B 1 468 ? 105.117 169.681 132.022 1.00 88.50  ? 468 ARG B NH1 1 
ATOM   5061 N NH2 . ARG B 1 468 ? 103.540 168.665 133.332 1.00 91.68  ? 468 ARG B NH2 1 
ATOM   5062 N N   . ASP B 1 469 ? 105.592 165.854 124.956 1.00 93.66  ? 469 ASP B N   1 
ATOM   5063 C CA  . ASP B 1 469 ? 106.239 165.979 123.657 1.00 94.68  ? 469 ASP B CA  1 
ATOM   5064 C C   . ASP B 1 469 ? 105.714 164.959 122.652 1.00 96.45  ? 469 ASP B C   1 
ATOM   5065 O O   . ASP B 1 469 ? 105.627 165.257 121.456 1.00 98.50  ? 469 ASP B O   1 
ATOM   5066 C CB  . ASP B 1 469 ? 107.752 165.843 123.810 1.00 95.60  ? 469 ASP B CB  1 
ATOM   5067 C CG  . ASP B 1 469 ? 108.346 166.924 124.690 1.00 101.12 ? 469 ASP B CG  1 
ATOM   5068 O OD1 . ASP B 1 469 ? 107.568 167.661 125.332 1.00 104.51 ? 469 ASP B OD1 1 
ATOM   5069 O OD2 . ASP B 1 469 ? 109.587 167.041 124.736 1.00 102.63 ? 469 ASP B OD2 1 
ATOM   5070 N N   . THR B 1 470 ? 105.359 163.756 123.108 1.00 95.38  ? 470 THR B N   1 
ATOM   5071 C CA  . THR B 1 470 ? 105.017 162.671 122.199 1.00 96.93  ? 470 THR B CA  1 
ATOM   5072 C C   . THR B 1 470 ? 103.561 162.237 122.253 1.00 98.89  ? 470 THR B C   1 
ATOM   5073 O O   . THR B 1 470 ? 103.101 161.580 121.314 1.00 102.87 ? 470 THR B O   1 
ATOM   5074 C CB  . THR B 1 470 ? 105.895 161.445 122.479 1.00 98.14  ? 470 THR B CB  1 
ATOM   5075 O OG1 . THR B 1 470 ? 105.887 161.165 123.885 1.00 97.65  ? 470 THR B OG1 1 
ATOM   5076 C CG2 . THR B 1 470 ? 107.322 161.696 122.020 1.00 97.09  ? 470 THR B CG2 1 
ATOM   5077 N N   . LYS B 1 471 ? 102.835 162.572 123.320 1.00 99.01  ? 471 LYS B N   1 
ATOM   5078 C CA  . LYS B 1 471 ? 101.427 162.200 123.475 1.00 102.17 ? 471 LYS B CA  1 
ATOM   5079 C C   . LYS B 1 471 ? 101.229 160.688 123.424 1.00 105.84 ? 471 LYS B C   1 
ATOM   5080 O O   . LYS B 1 471 ? 100.173 160.204 123.010 1.00 108.64 ? 471 LYS B O   1 
ATOM   5081 C CB  . LYS B 1 471 ? 100.549 162.890 122.427 1.00 101.54 ? 471 LYS B CB  1 
ATOM   5082 C CG  . LYS B 1 471 ? 100.704 164.400 122.380 1.00 101.13 ? 471 LYS B CG  1 
ATOM   5083 C CD  . LYS B 1 471 ? 100.449 165.027 123.738 1.00 102.18 ? 471 LYS B CD  1 
ATOM   5084 C CE  . LYS B 1 471 ? 100.432 166.542 123.643 1.00 98.38  ? 471 LYS B CE  1 
ATOM   5085 N NZ  . LYS B 1 471 ? 101.665 167.064 122.994 1.00 94.31  ? 471 LYS B NZ  1 
ATOM   5086 N N   . ARG B 1 472 ? 102.236 159.929 123.848 1.00 104.64 ? 472 ARG B N   1 
ATOM   5087 C CA  . ARG B 1 472 ? 102.158 158.473 123.894 1.00 102.37 ? 472 ARG B CA  1 
ATOM   5088 C C   . ARG B 1 472 ? 101.997 158.058 125.350 1.00 100.49 ? 472 ARG B C   1 
ATOM   5089 O O   . ARG B 1 472 ? 102.933 158.179 126.146 1.00 95.72  ? 472 ARG B O   1 
ATOM   5090 C CB  . ARG B 1 472 ? 103.396 157.837 123.266 1.00 97.67  ? 472 ARG B CB  1 
ATOM   5091 C CG  . ARG B 1 472 ? 103.716 158.357 121.875 1.00 96.04  ? 472 ARG B CG  1 
ATOM   5092 C CD  . ARG B 1 472 ? 104.459 157.326 121.046 1.00 98.76  ? 472 ARG B CD  1 
ATOM   5093 N NE  . ARG B 1 472 ? 103.616 156.180 120.728 1.00 103.71 ? 472 ARG B NE  1 
ATOM   5094 C CZ  . ARG B 1 472 ? 103.665 155.013 121.356 1.00 99.20  ? 472 ARG B CZ  1 
ATOM   5095 N NH1 . ARG B 1 472 ? 104.529 154.789 122.331 1.00 94.82  ? 472 ARG B NH1 1 
ATOM   5096 N NH2 . ARG B 1 472 ? 102.827 154.046 120.993 1.00 99.46  ? 472 ARG B NH2 1 
ATOM   5097 N N   . ALA B 1 473 ? 100.808 157.565 125.695 1.00 97.38  ? 473 ALA B N   1 
ATOM   5098 C CA  . ALA B 1 473 ? 100.487 157.295 127.090 1.00 89.68  ? 473 ALA B CA  1 
ATOM   5099 C C   . ALA B 1 473 ? 101.161 156.036 127.614 1.00 89.34  ? 473 ALA B C   1 
ATOM   5100 O O   . ALA B 1 473 ? 101.466 155.959 128.808 1.00 87.47  ? 473 ALA B O   1 
ATOM   5101 C CB  . ALA B 1 473 ? 98.973  157.181 127.268 1.00 89.02  ? 473 ALA B CB  1 
ATOM   5102 N N   . PHE B 1 474 ? 101.398 155.038 126.753 1.00 91.29  ? 474 PHE B N   1 
ATOM   5103 C CA  . PHE B 1 474 ? 101.908 153.762 127.256 1.00 88.81  ? 474 PHE B CA  1 
ATOM   5104 C C   . PHE B 1 474 ? 103.330 153.875 127.795 1.00 87.93  ? 474 PHE B C   1 
ATOM   5105 O O   . PHE B 1 474 ? 103.526 153.703 129.008 1.00 87.07  ? 474 PHE B O   1 
ATOM   5106 C CB  . PHE B 1 474 ? 101.790 152.682 126.180 1.00 84.90  ? 474 PHE B CB  1 
ATOM   5107 C CG  . PHE B 1 474 ? 102.761 151.555 126.361 1.00 81.14  ? 474 PHE B CG  1 
ATOM   5108 C CD1 . PHE B 1 474 ? 102.638 150.682 127.427 1.00 78.84  ? 474 PHE B CD1 1 
ATOM   5109 C CD2 . PHE B 1 474 ? 103.806 151.375 125.475 1.00 83.39  ? 474 PHE B CD2 1 
ATOM   5110 C CE1 . PHE B 1 474 ? 103.535 149.651 127.601 1.00 81.07  ? 474 PHE B CE1 1 
ATOM   5111 C CE2 . PHE B 1 474 ? 104.705 150.344 125.645 1.00 85.99  ? 474 PHE B CE2 1 
ATOM   5112 C CZ  . PHE B 1 474 ? 104.568 149.480 126.709 1.00 82.32  ? 474 PHE B CZ  1 
ATOM   5113 N N   . PRO B 1 475 ? 104.350 154.165 126.980 1.00 85.07  ? 475 PRO B N   1 
ATOM   5114 C CA  . PRO B 1 475 ? 105.724 153.969 127.461 1.00 81.69  ? 475 PRO B CA  1 
ATOM   5115 C C   . PRO B 1 475 ? 106.156 154.962 128.518 1.00 83.53  ? 475 PRO B C   1 
ATOM   5116 O O   . PRO B 1 475 ? 107.219 154.765 129.118 1.00 85.03  ? 475 PRO B O   1 
ATOM   5117 C CB  . PRO B 1 475 ? 106.558 154.124 126.189 1.00 79.93  ? 475 PRO B CB  1 
ATOM   5118 C CG  . PRO B 1 475 ? 105.799 155.103 125.399 1.00 85.22  ? 475 PRO B CG  1 
ATOM   5119 C CD  . PRO B 1 475 ? 104.339 154.842 125.672 1.00 85.33  ? 475 PRO B CD  1 
ATOM   5120 N N   . HIS B 1 476 ? 105.379 156.012 128.774 1.00 86.51  ? 476 HIS B N   1 
ATOM   5121 C CA  . HIS B 1 476 ? 105.813 157.082 129.663 1.00 87.25  ? 476 HIS B CA  1 
ATOM   5122 C C   . HIS B 1 476 ? 104.923 157.248 130.885 1.00 83.13  ? 476 HIS B C   1 
ATOM   5123 O O   . HIS B 1 476 ? 105.436 157.351 132.006 1.00 75.54  ? 476 HIS B O   1 
ATOM   5124 C CB  . HIS B 1 476 ? 105.893 158.396 128.876 1.00 86.40  ? 476 HIS B CB  1 
ATOM   5125 C CG  . HIS B 1 476 ? 106.726 158.302 127.636 1.00 83.12  ? 476 HIS B CG  1 
ATOM   5126 N ND1 . HIS B 1 476 ? 106.185 158.356 126.371 1.00 86.12  ? 476 HIS B ND1 1 
ATOM   5127 C CD2 . HIS B 1 476 ? 108.060 158.147 127.469 1.00 79.82  ? 476 HIS B CD2 1 
ATOM   5128 C CE1 . HIS B 1 476 ? 107.150 158.247 125.476 1.00 85.55  ? 476 HIS B CE1 1 
ATOM   5129 N NE2 . HIS B 1 476 ? 108.298 158.117 126.117 1.00 82.91  ? 476 HIS B NE2 1 
ATOM   5130 N N   . LEU B 1 477 ? 103.600 157.286 130.708 1.00 85.87  ? 477 LEU B N   1 
ATOM   5131 C CA  . LEU B 1 477 ? 102.711 157.417 131.858 1.00 82.02  ? 477 LEU B CA  1 
ATOM   5132 C C   . LEU B 1 477 ? 102.788 156.193 132.760 1.00 81.62  ? 477 LEU B C   1 
ATOM   5133 O O   . LEU B 1 477 ? 102.738 156.319 133.989 1.00 83.32  ? 477 LEU B O   1 
ATOM   5134 C CB  . LEU B 1 477 ? 101.276 157.654 131.398 1.00 83.49  ? 477 LEU B CB  1 
ATOM   5135 C CG  . LEU B 1 477 ? 100.982 159.043 130.834 1.00 88.69  ? 477 LEU B CG  1 
ATOM   5136 C CD1 . LEU B 1 477 ? 99.543  159.131 130.373 1.00 90.86  ? 477 LEU B CD1 1 
ATOM   5137 C CD2 . LEU B 1 477 ? 101.279 160.106 131.876 1.00 85.43  ? 477 LEU B CD2 1 
ATOM   5138 N N   . VAL B 1 478 ? 102.895 155.001 132.173 1.00 80.33  ? 478 VAL B N   1 
ATOM   5139 C CA  . VAL B 1 478 ? 103.077 153.800 132.981 1.00 75.95  ? 478 VAL B CA  1 
ATOM   5140 C C   . VAL B 1 478 ? 104.398 153.866 133.739 1.00 75.49  ? 478 VAL B C   1 
ATOM   5141 O O   . VAL B 1 478 ? 104.469 153.528 134.927 1.00 76.45  ? 478 VAL B O   1 
ATOM   5142 C CB  . VAL B 1 478 ? 102.980 152.547 132.092 1.00 70.73  ? 478 VAL B CB  1 
ATOM   5143 C CG1 . VAL B 1 478 ? 103.035 151.293 132.931 1.00 68.68  ? 478 VAL B CG1 1 
ATOM   5144 C CG2 . VAL B 1 478 ? 101.695 152.579 131.291 1.00 74.31  ? 478 VAL B CG2 1 
ATOM   5145 N N   . ASN B 1 479 ? 105.459 154.323 133.074 1.00 72.26  ? 479 ASN B N   1 
ATOM   5146 C CA  . ASN B 1 479 ? 106.741 154.518 133.741 1.00 69.51  ? 479 ASN B CA  1 
ATOM   5147 C C   . ASN B 1 479 ? 106.628 155.575 134.836 1.00 76.82  ? 479 ASN B C   1 
ATOM   5148 O O   . ASN B 1 479 ? 107.229 155.456 135.912 1.00 77.65  ? 479 ASN B O   1 
ATOM   5149 C CB  . ASN B 1 479 ? 107.794 154.907 132.706 1.00 68.31  ? 479 ASN B CB  1 
ATOM   5150 C CG  . ASN B 1 479 ? 109.198 154.844 133.253 1.00 69.15  ? 479 ASN B CG  1 
ATOM   5151 O OD1 . ASN B 1 479 ? 109.439 154.255 134.302 1.00 72.84  ? 479 ASN B OD1 1 
ATOM   5152 N ND2 . ASN B 1 479 ? 110.138 155.445 132.538 1.00 65.37  ? 479 ASN B ND2 1 
ATOM   5153 N N   . ALA B 1 480 ? 105.853 156.629 134.568 1.00 77.89  ? 480 ALA B N   1 
ATOM   5154 C CA  . ALA B 1 480 ? 105.637 157.666 135.571 1.00 76.78  ? 480 ALA B CA  1 
ATOM   5155 C C   . ALA B 1 480 ? 104.950 157.106 136.808 1.00 73.23  ? 480 ALA B C   1 
ATOM   5156 O O   . ALA B 1 480 ? 105.307 157.455 137.938 1.00 68.93  ? 480 ALA B O   1 
ATOM   5157 C CB  . ALA B 1 480 ? 104.820 158.809 134.972 1.00 78.67  ? 480 ALA B CB  1 
ATOM   5158 N N   . GLY B 1 481 ? 103.954 156.242 136.615 1.00 70.75  ? 481 GLY B N   1 
ATOM   5159 C CA  . GLY B 1 481 ? 103.342 155.577 137.753 1.00 68.71  ? 481 GLY B CA  1 
ATOM   5160 C C   . GLY B 1 481 ? 104.319 154.675 138.480 1.00 66.59  ? 481 GLY B C   1 
ATOM   5161 O O   . GLY B 1 481 ? 104.310 154.593 139.714 1.00 72.18  ? 481 GLY B O   1 
ATOM   5162 N N   . LYS B 1 482 ? 105.178 153.986 137.722 1.00 64.39  ? 482 LYS B N   1 
ATOM   5163 C CA  . LYS B 1 482 ? 106.222 153.169 138.332 1.00 67.94  ? 482 LYS B CA  1 
ATOM   5164 C C   . LYS B 1 482 ? 107.073 153.995 139.280 1.00 70.80  ? 482 LYS B C   1 
ATOM   5165 O O   . LYS B 1 482 ? 107.396 153.552 140.388 1.00 73.04  ? 482 LYS B O   1 
ATOM   5166 C CB  . LYS B 1 482 ? 107.103 152.539 137.254 1.00 69.09  ? 482 LYS B CB  1 
ATOM   5167 C CG  . LYS B 1 482 ? 108.562 152.397 137.659 1.00 63.70  ? 482 LYS B CG  1 
ATOM   5168 C CD  . LYS B 1 482 ? 109.384 151.748 136.564 1.00 67.30  ? 482 LYS B CD  1 
ATOM   5169 C CE  . LYS B 1 482 ? 110.864 151.945 136.808 1.00 70.04  ? 482 LYS B CE  1 
ATOM   5170 N NZ  . LYS B 1 482 ? 111.194 151.775 138.242 1.00 70.11  ? 482 LYS B NZ  1 
ATOM   5171 N N   . TYR B 1 483 ? 107.441 155.203 138.862 1.00 72.66  ? 483 TYR B N   1 
ATOM   5172 C CA  . TYR B 1 483 ? 108.256 156.047 139.729 1.00 70.03  ? 483 TYR B CA  1 
ATOM   5173 C C   . TYR B 1 483 ? 107.441 156.643 140.872 1.00 72.25  ? 483 TYR B C   1 
ATOM   5174 O O   . TYR B 1 483 ? 107.965 156.831 141.973 1.00 72.27  ? 483 TYR B O   1 
ATOM   5175 C CB  . TYR B 1 483 ? 108.934 157.143 138.913 1.00 62.83  ? 483 TYR B CB  1 
ATOM   5176 C CG  . TYR B 1 483 ? 110.140 156.642 138.162 1.00 58.41  ? 483 TYR B CG  1 
ATOM   5177 C CD1 . TYR B 1 483 ? 111.272 156.221 138.840 1.00 59.34  ? 483 TYR B CD1 1 
ATOM   5178 C CD2 . TYR B 1 483 ? 110.149 156.588 136.779 1.00 60.88  ? 483 TYR B CD2 1 
ATOM   5179 C CE1 . TYR B 1 483 ? 112.372 155.760 138.166 1.00 58.22  ? 483 TYR B CE1 1 
ATOM   5180 C CE2 . TYR B 1 483 ? 111.249 156.131 136.097 1.00 61.11  ? 483 TYR B CE2 1 
ATOM   5181 C CZ  . TYR B 1 483 ? 112.356 155.718 136.796 1.00 58.95  ? 483 TYR B CZ  1 
ATOM   5182 O OH  . TYR B 1 483 ? 113.458 155.257 136.120 1.00 59.00  ? 483 TYR B OH  1 
ATOM   5183 N N   . SER B 1 484 ? 106.162 156.938 140.639 1.00 69.24  ? 484 SER B N   1 
ATOM   5184 C CA  . SER B 1 484 ? 105.325 157.476 141.705 1.00 70.13  ? 484 SER B CA  1 
ATOM   5185 C C   . SER B 1 484 ? 105.073 156.454 142.802 1.00 76.50  ? 484 SER B C   1 
ATOM   5186 O O   . SER B 1 484 ? 104.720 156.833 143.929 1.00 81.93  ? 484 SER B O   1 
ATOM   5187 C CB  . SER B 1 484 ? 103.995 157.959 141.138 1.00 72.15  ? 484 SER B CB  1 
ATOM   5188 O OG  . SER B 1 484 ? 103.253 156.872 140.622 1.00 74.43  ? 484 SER B OG  1 
ATOM   5189 N N   . THR B 1 485 ? 105.212 155.166 142.486 1.00 75.67  ? 485 THR B N   1 
ATOM   5190 C CA  . THR B 1 485 ? 105.166 154.159 143.540 1.00 75.38  ? 485 THR B CA  1 
ATOM   5191 C C   . THR B 1 485 ? 106.211 154.432 144.610 1.00 82.32  ? 485 THR B C   1 
ATOM   5192 O O   . THR B 1 485 ? 105.980 154.139 145.787 1.00 86.61  ? 485 THR B O   1 
ATOM   5193 C CB  . THR B 1 485 ? 105.372 152.763 142.964 1.00 69.78  ? 485 THR B CB  1 
ATOM   5194 O OG1 . THR B 1 485 ? 106.582 152.738 142.200 1.00 70.96  ? 485 THR B OG1 1 
ATOM   5195 C CG2 . THR B 1 485 ? 104.203 152.382 142.087 1.00 70.69  ? 485 THR B CG2 1 
ATOM   5196 N N   . THR B 1 486 ? 107.361 154.991 144.224 1.00 81.17  ? 486 THR B N   1 
ATOM   5197 C CA  . THR B 1 486 ? 108.370 155.365 145.209 1.00 83.01  ? 486 THR B CA  1 
ATOM   5198 C C   . THR B 1 486 ? 107.842 156.438 146.151 1.00 85.79  ? 486 THR B C   1 
ATOM   5199 O O   . THR B 1 486 ? 108.023 156.352 147.372 1.00 88.80  ? 486 THR B O   1 
ATOM   5200 C CB  . THR B 1 486 ? 109.640 155.849 144.512 1.00 75.18  ? 486 THR B CB  1 
ATOM   5201 O OG1 . THR B 1 486 ? 110.203 154.779 143.747 1.00 78.39  ? 486 THR B OG1 1 
ATOM   5202 C CG2 . THR B 1 486 ? 110.655 156.306 145.530 1.00 75.92  ? 486 THR B CG2 1 
ATOM   5203 N N   . PHE B 1 487 ? 107.182 157.462 145.599 1.00 82.19  ? 487 PHE B N   1 
ATOM   5204 C CA  . PHE B 1 487 ? 106.604 158.499 146.448 1.00 87.13  ? 487 PHE B CA  1 
ATOM   5205 C C   . PHE B 1 487 ? 105.600 157.899 147.414 1.00 87.16  ? 487 PHE B C   1 
ATOM   5206 O O   . PHE B 1 487 ? 105.619 158.202 148.611 1.00 90.49  ? 487 PHE B O   1 
ATOM   5207 C CB  . PHE B 1 487 ? 105.916 159.574 145.607 1.00 82.22  ? 487 PHE B CB  1 
ATOM   5208 C CG  . PHE B 1 487 ? 106.752 160.110 144.486 1.00 82.74  ? 487 PHE B CG  1 
ATOM   5209 C CD1 . PHE B 1 487 ? 108.112 160.297 144.633 1.00 83.92  ? 487 PHE B CD1 1 
ATOM   5210 C CD2 . PHE B 1 487 ? 106.163 160.438 143.279 1.00 75.87  ? 487 PHE B CD2 1 
ATOM   5211 C CE1 . PHE B 1 487 ? 108.867 160.793 143.590 1.00 77.54  ? 487 PHE B CE1 1 
ATOM   5212 C CE2 . PHE B 1 487 ? 106.911 160.931 142.241 1.00 68.33  ? 487 PHE B CE2 1 
ATOM   5213 C CZ  . PHE B 1 487 ? 108.261 161.109 142.393 1.00 68.96  ? 487 PHE B CZ  1 
ATOM   5214 N N   . PHE B 1 488 ? 104.718 157.039 146.905 1.00 85.27  ? 488 PHE B N   1 
ATOM   5215 C CA  . PHE B 1 488 ? 103.697 156.440 147.757 1.00 90.46  ? 488 PHE B CA  1 
ATOM   5216 C C   . PHE B 1 488 ? 104.325 155.615 148.872 1.00 90.64  ? 488 PHE B C   1 
ATOM   5217 O O   . PHE B 1 488 ? 103.939 155.730 150.043 1.00 96.85  ? 488 PHE B O   1 
ATOM   5218 C CB  . PHE B 1 488 ? 102.753 155.580 146.920 1.00 93.00  ? 488 PHE B CB  1 
ATOM   5219 C CG  . PHE B 1 488 ? 101.615 156.344 146.320 1.00 97.29  ? 488 PHE B CG  1 
ATOM   5220 C CD1 . PHE B 1 488 ? 100.506 156.664 147.080 1.00 96.09  ? 488 PHE B CD1 1 
ATOM   5221 C CD2 . PHE B 1 488 ? 101.653 156.744 144.998 1.00 94.68  ? 488 PHE B CD2 1 
ATOM   5222 C CE1 . PHE B 1 488 ? 99.456  157.368 146.534 1.00 97.04  ? 488 PHE B CE1 1 
ATOM   5223 C CE2 . PHE B 1 488 ? 100.607 157.448 144.446 1.00 94.62  ? 488 PHE B CE2 1 
ATOM   5224 C CZ  . PHE B 1 488 ? 99.506  157.760 145.215 1.00 97.65  ? 488 PHE B CZ  1 
ATOM   5225 N N   . MET B 1 489 ? 105.307 154.784 148.525 1.00 84.82  ? 489 MET B N   1 
ATOM   5226 C CA  . MET B 1 489 ? 105.927 153.910 149.511 1.00 86.19  ? 489 MET B CA  1 
ATOM   5227 C C   . MET B 1 489 ? 106.656 154.710 150.581 1.00 91.70  ? 489 MET B C   1 
ATOM   5228 O O   . MET B 1 489 ? 106.532 154.423 151.778 1.00 94.86  ? 489 MET B O   1 
ATOM   5229 C CB  . MET B 1 489 ? 106.883 152.948 148.816 1.00 81.86  ? 489 MET B CB  1 
ATOM   5230 C CG  . MET B 1 489 ? 107.661 152.106 149.781 1.00 85.69  ? 489 MET B CG  1 
ATOM   5231 S SD  . MET B 1 489 ? 108.824 151.000 148.989 1.00 93.48  ? 489 MET B SD  1 
ATOM   5232 C CE  . MET B 1 489 ? 109.572 150.319 150.454 1.00 86.46  ? 489 MET B CE  1 
ATOM   5233 N N   . VAL B 1 490 ? 107.415 155.727 150.170 1.00 89.11  ? 490 VAL B N   1 
ATOM   5234 C CA  . VAL B 1 490 ? 108.160 156.518 151.142 1.00 90.91  ? 490 VAL B CA  1 
ATOM   5235 C C   . VAL B 1 490 ? 107.209 157.320 152.020 1.00 99.05  ? 490 VAL B C   1 
ATOM   5236 O O   . VAL B 1 490 ? 107.437 157.469 153.227 1.00 102.72 ? 490 VAL B O   1 
ATOM   5237 C CB  . VAL B 1 490 ? 109.176 157.419 150.423 1.00 89.22  ? 490 VAL B CB  1 
ATOM   5238 C CG1 . VAL B 1 490 ? 109.925 158.274 151.422 1.00 92.25  ? 490 VAL B CG1 1 
ATOM   5239 C CG2 . VAL B 1 490 ? 110.144 156.567 149.635 1.00 86.91  ? 490 VAL B CG2 1 
ATOM   5240 N N   . THR B 1 491 ? 106.127 157.843 151.438 1.00 98.50  ? 491 THR B N   1 
ATOM   5241 C CA  . THR B 1 491 ? 105.142 158.570 152.229 1.00 101.27 ? 491 THR B CA  1 
ATOM   5242 C C   . THR B 1 491 ? 104.511 157.671 153.279 1.00 103.51 ? 491 THR B C   1 
ATOM   5243 O O   . THR B 1 491 ? 104.363 158.068 154.442 1.00 106.71 ? 491 THR B O   1 
ATOM   5244 C CB  . THR B 1 491 ? 104.067 159.153 151.315 1.00 102.96 ? 491 THR B CB  1 
ATOM   5245 O OG1 . THR B 1 491 ? 104.612 160.254 150.578 1.00 110.51 ? 491 THR B OG1 1 
ATOM   5246 C CG2 . THR B 1 491 ? 102.875 159.629 152.125 1.00 104.68 ? 491 THR B CG2 1 
ATOM   5247 N N   . PHE B 1 492 ? 104.137 156.453 152.890 1.00 102.09 ? 492 PHE B N   1 
ATOM   5248 C CA  . PHE B 1 492 ? 103.533 155.540 153.853 1.00 103.86 ? 492 PHE B CA  1 
ATOM   5249 C C   . PHE B 1 492 ? 104.531 155.130 154.927 1.00 109.81 ? 492 PHE B C   1 
ATOM   5250 O O   . PHE B 1 492 ? 104.165 155.008 156.100 1.00 115.32 ? 492 PHE B O   1 
ATOM   5251 C CB  . PHE B 1 492 ? 102.955 154.329 153.130 1.00 101.32 ? 492 PHE B CB  1 
ATOM   5252 C CG  . PHE B 1 492 ? 101.711 154.644 152.357 1.00 103.29 ? 492 PHE B CG  1 
ATOM   5253 C CD1 . PHE B 1 492 ? 100.831 155.607 152.818 1.00 101.79 ? 492 PHE B CD1 1 
ATOM   5254 C CD2 . PHE B 1 492 ? 101.430 154.005 151.169 1.00 101.85 ? 492 PHE B CD2 1 
ATOM   5255 C CE1 . PHE B 1 492 ? 99.690  155.914 152.115 1.00 100.69 ? 492 PHE B CE1 1 
ATOM   5256 C CE2 . PHE B 1 492 ? 100.291 154.312 150.462 1.00 99.30  ? 492 PHE B CE2 1 
ATOM   5257 C CZ  . PHE B 1 492 ? 99.420  155.266 150.936 1.00 101.18 ? 492 PHE B CZ  1 
ATOM   5258 N N   . ALA B 1 493 ? 105.797 154.938 154.554 1.00 109.48 ? 493 ALA B N   1 
ATOM   5259 C CA  . ALA B 1 493 ? 106.820 154.633 155.550 1.00 109.89 ? 493 ALA B CA  1 
ATOM   5260 C C   . ALA B 1 493 ? 106.962 155.768 156.557 1.00 113.29 ? 493 ALA B C   1 
ATOM   5261 O O   . ALA B 1 493 ? 107.025 155.537 157.772 1.00 117.14 ? 493 ALA B O   1 
ATOM   5262 C CB  . ALA B 1 493 ? 108.155 154.360 154.859 1.00 104.25 ? 493 ALA B CB  1 
ATOM   5263 N N   . ALA B 1 494 ? 107.012 157.007 156.064 1.00 109.14 ? 494 ALA B N   1 
ATOM   5264 C CA  . ALA B 1 494 ? 107.163 158.151 156.954 1.00 112.71 ? 494 ALA B CA  1 
ATOM   5265 C C   . ALA B 1 494 ? 105.963 158.291 157.880 1.00 119.53 ? 494 ALA B C   1 
ATOM   5266 O O   . ALA B 1 494 ? 106.122 158.535 159.082 1.00 121.88 ? 494 ALA B O   1 
ATOM   5267 C CB  . ALA B 1 494 ? 107.366 159.426 156.138 1.00 109.73 ? 494 ALA B CB  1 
ATOM   5268 N N   . LEU B 1 495 ? 104.752 158.137 157.339 1.00 119.80 ? 495 LEU B N   1 
ATOM   5269 C CA  . LEU B 1 495 ? 103.558 158.230 158.173 1.00 122.59 ? 495 LEU B CA  1 
ATOM   5270 C C   . LEU B 1 495 ? 103.534 157.126 159.222 1.00 124.40 ? 495 LEU B C   1 
ATOM   5271 O O   . LEU B 1 495 ? 103.193 157.372 160.384 1.00 128.52 ? 495 LEU B O   1 
ATOM   5272 C CB  . LEU B 1 495 ? 102.302 158.176 157.304 1.00 122.89 ? 495 LEU B CB  1 
ATOM   5273 C CG  . LEU B 1 495 ? 102.059 159.386 156.399 1.00 122.26 ? 495 LEU B CG  1 
ATOM   5274 C CD1 . LEU B 1 495 ? 100.837 159.172 155.522 1.00 119.18 ? 495 LEU B CD1 1 
ATOM   5275 C CD2 . LEU B 1 495 ? 101.908 160.649 157.229 1.00 122.24 ? 495 LEU B CD2 1 
ATOM   5276 N N   . TYR B 1 496 ? 103.905 155.905 158.829 1.00 120.61 ? 496 TYR B N   1 
ATOM   5277 C CA  . TYR B 1 496 ? 103.949 154.791 159.769 1.00 121.18 ? 496 TYR B CA  1 
ATOM   5278 C C   . TYR B 1 496 ? 104.913 155.076 160.911 1.00 125.32 ? 496 TYR B C   1 
ATOM   5279 O O   . TYR B 1 496 ? 104.570 154.907 162.088 1.00 128.97 ? 496 TYR B O   1 
ATOM   5280 C CB  . TYR B 1 496 ? 104.347 153.517 159.021 1.00 119.75 ? 496 TYR B CB  1 
ATOM   5281 C CG  . TYR B 1 496 ? 104.788 152.364 159.894 1.00 123.50 ? 496 TYR B CG  1 
ATOM   5282 C CD1 . TYR B 1 496 ? 106.129 152.165 160.191 1.00 124.89 ? 496 TYR B CD1 1 
ATOM   5283 C CD2 . TYR B 1 496 ? 103.866 151.460 160.399 1.00 124.30 ? 496 TYR B CD2 1 
ATOM   5284 C CE1 . TYR B 1 496 ? 106.538 151.110 160.979 1.00 126.56 ? 496 TYR B CE1 1 
ATOM   5285 C CE2 . TYR B 1 496 ? 104.265 150.402 161.188 1.00 125.16 ? 496 TYR B CE2 1 
ATOM   5286 C CZ  . TYR B 1 496 ? 105.602 150.231 161.474 1.00 128.68 ? 496 TYR B CZ  1 
ATOM   5287 O OH  . TYR B 1 496 ? 106.004 149.177 162.261 1.00 130.93 ? 496 TYR B OH  1 
ATOM   5288 N N   . SER B 1 497 ? 106.128 155.521 160.582 1.00 125.19 ? 497 SER B N   1 
ATOM   5289 C CA  . SER B 1 497 ? 107.115 155.786 161.624 1.00 127.24 ? 497 SER B CA  1 
ATOM   5290 C C   . SER B 1 497 ? 106.679 156.930 162.529 1.00 130.91 ? 497 SER B C   1 
ATOM   5291 O O   . SER B 1 497 ? 106.821 156.850 163.756 1.00 135.27 ? 497 SER B O   1 
ATOM   5292 C CB  . SER B 1 497 ? 108.472 156.090 160.996 1.00 126.82 ? 497 SER B CB  1 
ATOM   5293 O OG  . SER B 1 497 ? 109.430 156.397 161.992 1.00 126.77 ? 497 SER B OG  1 
ATOM   5294 N N   . THR B 1 498 ? 106.149 158.007 161.944 1.00 128.01 ? 498 THR B N   1 
ATOM   5295 C CA  . THR B 1 498 ? 105.725 159.147 162.749 1.00 130.22 ? 498 THR B CA  1 
ATOM   5296 C C   . THR B 1 498 ? 104.590 158.767 163.689 1.00 136.11 ? 498 THR B C   1 
ATOM   5297 O O   . THR B 1 498 ? 104.582 159.172 164.857 1.00 137.53 ? 498 THR B O   1 
ATOM   5298 C CB  . THR B 1 498 ? 105.307 160.305 161.844 1.00 129.06 ? 498 THR B CB  1 
ATOM   5299 O OG1 . THR B 1 498 ? 106.389 160.640 160.967 1.00 130.12 ? 498 THR B OG1 1 
ATOM   5300 C CG2 . THR B 1 498 ? 104.944 161.525 162.676 1.00 129.75 ? 498 THR B CG2 1 
ATOM   5301 N N   . HIS B 1 499 ? 103.623 157.985 163.203 1.00 137.46 ? 499 HIS B N   1 
ATOM   5302 C CA  . HIS B 1 499 ? 102.519 157.572 164.062 1.00 140.09 ? 499 HIS B CA  1 
ATOM   5303 C C   . HIS B 1 499 ? 102.985 156.601 165.138 1.00 141.50 ? 499 HIS B C   1 
ATOM   5304 O O   . HIS B 1 499 ? 102.478 156.631 166.265 1.00 146.40 ? 499 HIS B O   1 
ATOM   5305 C CB  . HIS B 1 499 ? 101.398 156.959 163.225 1.00 139.40 ? 499 HIS B CB  1 
ATOM   5306 C CG  . HIS B 1 499 ? 100.471 157.973 162.632 1.00 145.48 ? 499 HIS B CG  1 
ATOM   5307 N ND1 . HIS B 1 499 ? 99.192  158.177 163.104 1.00 149.29 ? 499 HIS B ND1 1 
ATOM   5308 C CD2 . HIS B 1 499 ? 100.641 158.852 161.616 1.00 147.60 ? 499 HIS B CD2 1 
ATOM   5309 C CE1 . HIS B 1 499 ? 98.612  159.132 162.400 1.00 150.93 ? 499 HIS B CE1 1 
ATOM   5310 N NE2 . HIS B 1 499 ? 99.470  159.559 161.491 1.00 151.99 ? 499 HIS B NE2 1 
ATOM   5311 N N   . LYS B 1 500 ? 103.942 155.728 164.815 1.00 137.68 ? 500 LYS B N   1 
ATOM   5312 C CA  . LYS B 1 500 ? 104.468 154.830 165.837 1.00 138.30 ? 500 LYS B CA  1 
ATOM   5313 C C   . LYS B 1 500 ? 105.193 155.605 166.928 1.00 142.28 ? 500 LYS B C   1 
ATOM   5314 O O   . LYS B 1 500 ? 105.063 155.287 168.116 1.00 143.55 ? 500 LYS B O   1 
ATOM   5315 C CB  . LYS B 1 500 ? 105.393 153.788 165.213 1.00 133.18 ? 500 LYS B CB  1 
ATOM   5316 C CG  . LYS B 1 500 ? 105.963 152.814 166.229 1.00 133.50 ? 500 LYS B CG  1 
ATOM   5317 C CD  . LYS B 1 500 ? 106.479 151.545 165.580 1.00 132.69 ? 500 LYS B CD  1 
ATOM   5318 C CE  . LYS B 1 500 ? 106.912 150.537 166.635 1.00 130.87 ? 500 LYS B CE  1 
ATOM   5319 N NZ  . LYS B 1 500 ? 107.296 149.227 166.044 1.00 126.15 ? 500 LYS B NZ  1 
ATOM   5320 N N   . GLU B 1 501 ? 105.963 156.626 166.546 1.00 142.35 ? 501 GLU B N   1 
ATOM   5321 C CA  . GLU B 1 501 ? 106.667 157.422 167.546 1.00 142.39 ? 501 GLU B CA  1 
ATOM   5322 C C   . GLU B 1 501 ? 105.698 158.255 168.379 1.00 143.75 ? 501 GLU B C   1 
ATOM   5323 O O   . GLU B 1 501 ? 105.833 158.329 169.606 1.00 143.97 ? 501 GLU B O   1 
ATOM   5324 C CB  . GLU B 1 501 ? 107.707 158.316 166.872 1.00 141.83 ? 501 GLU B CB  1 
ATOM   5325 C CG  . GLU B 1 501 ? 108.857 157.550 166.241 1.00 139.16 ? 501 GLU B CG  1 
ATOM   5326 C CD  . GLU B 1 501 ? 109.936 158.463 165.695 1.00 137.62 ? 501 GLU B CD  1 
ATOM   5327 O OE1 . GLU B 1 501 ? 109.796 159.697 165.828 1.00 138.42 ? 501 GLU B OE1 1 
ATOM   5328 O OE2 . GLU B 1 501 ? 110.925 157.946 165.135 1.00 136.49 ? 501 GLU B OE2 1 
ATOM   5329 N N   . ARG B 1 502 ? 104.717 158.889 167.733 1.00 145.37 ? 502 ARG B N   1 
ATOM   5330 C CA  . ARG B 1 502 ? 103.771 159.724 168.469 1.00 149.75 ? 502 ARG B CA  1 
ATOM   5331 C C   . ARG B 1 502 ? 102.744 158.879 169.212 1.00 152.05 ? 502 ARG B C   1 
ATOM   5332 O O   . ARG B 1 502 ? 102.324 159.235 170.319 1.00 153.73 ? 502 ARG B O   1 
ATOM   5333 C CB  . ARG B 1 502 ? 103.076 160.697 167.518 1.00 149.06 ? 502 ARG B CB  1 
ATOM   5334 C CG  . ARG B 1 502 ? 104.008 161.708 166.875 1.00 150.63 ? 502 ARG B CG  1 
ATOM   5335 C CD  . ARG B 1 502 ? 103.256 162.630 165.931 1.00 150.90 ? 502 ARG B CD  1 
ATOM   5336 N NE  . ARG B 1 502 ? 102.333 163.511 166.636 1.00 154.68 ? 502 ARG B NE  1 
ATOM   5337 C CZ  . ARG B 1 502 ? 102.628 164.743 167.029 1.00 152.95 ? 502 ARG B CZ  1 
ATOM   5338 N NH1 . ARG B 1 502 ? 103.820 165.272 166.808 1.00 150.40 ? 502 ARG B NH1 1 
ATOM   5339 N NH2 . ARG B 1 502 ? 101.703 165.463 167.657 1.00 150.45 ? 502 ARG B NH2 1 
ATOM   5340 N N   . GLY B 1 503 ? 102.333 157.759 168.626 1.00 151.43 ? 503 GLY B N   1 
ATOM   5341 C CA  . GLY B 1 503 ? 101.342 156.905 169.248 1.00 151.10 ? 503 GLY B CA  1 
ATOM   5342 C C   . GLY B 1 503 ? 99.916  157.366 169.026 1.00 154.32 ? 503 GLY B C   1 
ATOM   5343 O O   . GLY B 1 503 ? 99.195  157.658 169.984 1.00 154.09 ? 503 GLY B O   1 
ATOM   5344 N N   . HIS B 1 504 ? 99.499  157.436 167.763 1.00 156.06 ? 504 HIS B N   1 
ATOM   5345 C CA  . HIS B 1 504 ? 98.126  157.766 167.406 1.00 157.87 ? 504 HIS B CA  1 
ATOM   5346 C C   . HIS B 1 504 ? 97.277  156.525 167.165 1.00 156.49 ? 504 HIS B C   1 
ATOM   5347 O O   . HIS B 1 504 ? 96.176  156.637 166.616 1.00 153.74 ? 504 HIS B O   1 
ATOM   5348 C CB  . HIS B 1 504 ? 98.097  158.669 166.172 1.00 157.94 ? 504 HIS B CB  1 
ATOM   5349 C CG  . HIS B 1 504 ? 98.565  160.067 166.433 1.00 159.03 ? 504 HIS B CG  1 
ATOM   5350 N ND1 . HIS B 1 504 ? 97.788  161.003 167.081 1.00 156.75 ? 504 HIS B ND1 1 
ATOM   5351 C CD2 . HIS B 1 504 ? 99.727  160.690 166.128 1.00 157.98 ? 504 HIS B CD2 1 
ATOM   5352 C CE1 . HIS B 1 504 ? 98.452  162.141 167.168 1.00 158.02 ? 504 HIS B CE1 1 
ATOM   5353 N NE2 . HIS B 1 504 ? 99.632  161.978 166.597 1.00 159.95 ? 504 HIS B NE2 1 
ATOM   5354 N N   . SER B 1 505 ? 97.779  155.348 167.537 1.00 156.41 ? 505 SER B N   1 
ATOM   5355 C CA  . SER B 1 505 ? 97.092  154.060 167.513 1.00 156.55 ? 505 SER B CA  1 
ATOM   5356 C C   . SER B 1 505 ? 96.815  153.545 166.107 1.00 156.74 ? 505 SER B C   1 
ATOM   5357 O O   . SER B 1 505 ? 96.298  152.430 165.969 1.00 155.39 ? 505 SER B O   1 
ATOM   5358 C CB  . SER B 1 505 ? 95.769  154.085 168.295 1.00 156.61 ? 505 SER B CB  1 
ATOM   5359 O OG  . SER B 1 505 ? 95.992  154.357 169.667 1.00 155.48 ? 505 SER B OG  1 
ATOM   5360 N N   . ASP B 1 506 ? 97.128  154.309 165.060 1.00 157.73 ? 506 ASP B N   1 
ATOM   5361 C CA  . ASP B 1 506 ? 96.958  153.794 163.705 1.00 155.90 ? 506 ASP B CA  1 
ATOM   5362 C C   . ASP B 1 506 ? 97.897  152.622 163.450 1.00 152.97 ? 506 ASP B C   1 
ATOM   5363 O O   . ASP B 1 506 ? 97.459  151.537 163.051 1.00 151.96 ? 506 ASP B O   1 
ATOM   5364 C CB  . ASP B 1 506 ? 97.189  154.912 162.688 1.00 154.09 ? 506 ASP B CB  1 
ATOM   5365 C CG  . ASP B 1 506 ? 96.244  156.081 162.885 1.00 157.58 ? 506 ASP B CG  1 
ATOM   5366 O OD1 . ASP B 1 506 ? 95.456  156.052 163.853 1.00 160.05 ? 506 ASP B OD1 1 
ATOM   5367 O OD2 . ASP B 1 506 ? 96.287  157.027 162.071 1.00 157.63 ? 506 ASP B OD2 1 
ATOM   5368 N N   . THR B 1 507 ? 99.192  152.820 163.709 1.00 152.41 ? 507 THR B N   1 
ATOM   5369 C CA  . THR B 1 507 ? 100.218 151.782 163.640 1.00 151.75 ? 507 THR B CA  1 
ATOM   5370 C C   . THR B 1 507 ? 100.073 150.865 162.431 1.00 146.08 ? 507 THR B C   1 
ATOM   5371 O O   . THR B 1 507 ? 100.334 151.273 161.292 1.00 140.87 ? 507 THR B O   1 
ATOM   5372 C CB  . THR B 1 507 ? 100.203 150.944 164.920 1.00 150.63 ? 507 THR B CB  1 
ATOM   5373 O OG1 . THR B 1 507 ? 98.947  150.262 165.034 1.00 150.83 ? 507 THR B OG1 1 
ATOM   5374 C CG2 . THR B 1 507 ? 100.405 151.831 166.140 1.00 147.49 ? 507 THR B CG2 1 
ATOM   5375 N N   . MET B 1 508 ? 99.634  149.626 162.677 1.00 145.46 ? 508 MET B N   1 
ATOM   5376 C CA  . MET B 1 508 ? 99.589  148.611 161.630 1.00 143.73 ? 508 MET B CA  1 
ATOM   5377 C C   . MET B 1 508 ? 98.707  149.016 160.459 1.00 141.02 ? 508 MET B C   1 
ATOM   5378 O O   . MET B 1 508 ? 98.895  148.497 159.353 1.00 136.13 ? 508 MET B O   1 
ATOM   5379 C CB  . MET B 1 508 ? 99.106  147.282 162.211 1.00 143.68 ? 508 MET B CB  1 
ATOM   5380 C CG  . MET B 1 508 ? 100.035 146.693 163.259 1.00 143.53 ? 508 MET B CG  1 
ATOM   5381 S SD  . MET B 1 508 ? 101.692 146.381 162.619 1.00 142.75 ? 508 MET B SD  1 
ATOM   5382 C CE  . MET B 1 508 ? 102.500 145.715 164.073 1.00 134.77 ? 508 MET B CE  1 
ATOM   5383 N N   . VAL B 1 509 ? 97.763  149.936 160.673 1.00 141.87 ? 509 VAL B N   1 
ATOM   5384 C CA  . VAL B 1 509 ? 96.939  150.425 159.573 1.00 138.93 ? 509 VAL B CA  1 
ATOM   5385 C C   . VAL B 1 509 ? 97.821  150.963 158.456 1.00 133.11 ? 509 VAL B C   1 
ATOM   5386 O O   . VAL B 1 509 ? 97.595  150.679 157.274 1.00 129.22 ? 509 VAL B O   1 
ATOM   5387 C CB  . VAL B 1 509 ? 95.949  151.491 160.077 1.00 141.04 ? 509 VAL B CB  1 
ATOM   5388 C CG1 . VAL B 1 509 ? 95.184  152.097 158.911 1.00 139.26 ? 509 VAL B CG1 1 
ATOM   5389 C CG2 . VAL B 1 509 ? 94.991  150.883 161.088 1.00 141.82 ? 509 VAL B CG2 1 
ATOM   5390 N N   . PHE B 1 510 ? 98.847  151.737 158.810 1.00 132.39 ? 510 PHE B N   1 
ATOM   5391 C CA  . PHE B 1 510 ? 99.814  152.150 157.802 1.00 128.62 ? 510 PHE B CA  1 
ATOM   5392 C C   . PHE B 1 510 ? 100.720 150.997 157.394 1.00 125.95 ? 510 PHE B C   1 
ATOM   5393 O O   . PHE B 1 510 ? 101.066 150.875 156.212 1.00 121.36 ? 510 PHE B O   1 
ATOM   5394 C CB  . PHE B 1 510 ? 100.641 153.325 158.312 1.00 126.45 ? 510 PHE B CB  1 
ATOM   5395 C CG  . PHE B 1 510 ? 99.862  154.597 158.443 1.00 128.77 ? 510 PHE B CG  1 
ATOM   5396 C CD1 . PHE B 1 510 ? 99.486  155.310 157.318 1.00 128.70 ? 510 PHE B CD1 1 
ATOM   5397 C CD2 . PHE B 1 510 ? 99.507  155.083 159.687 1.00 133.94 ? 510 PHE B CD2 1 
ATOM   5398 C CE1 . PHE B 1 510 ? 98.767  156.482 157.433 1.00 129.06 ? 510 PHE B CE1 1 
ATOM   5399 C CE2 . PHE B 1 510 ? 98.790  156.257 159.808 1.00 134.57 ? 510 PHE B CE2 1 
ATOM   5400 C CZ  . PHE B 1 510 ? 98.419  156.956 158.679 1.00 131.64 ? 510 PHE B CZ  1 
ATOM   5401 N N   . PHE B 1 511 ? 101.094 150.136 158.347 1.00 127.32 ? 511 PHE B N   1 
ATOM   5402 C CA  . PHE B 1 511 ? 102.058 149.078 158.061 1.00 124.00 ? 511 PHE B CA  1 
ATOM   5403 C C   . PHE B 1 511 ? 101.576 148.191 156.924 1.00 122.83 ? 511 PHE B C   1 
ATOM   5404 O O   . PHE B 1 511 ? 102.326 147.910 155.982 1.00 119.81 ? 511 PHE B O   1 
ATOM   5405 C CB  . PHE B 1 511 ? 102.318 148.246 159.316 1.00 129.22 ? 511 PHE B CB  1 
ATOM   5406 C CG  . PHE B 1 511 ? 103.280 147.109 159.105 1.00 131.67 ? 511 PHE B CG  1 
ATOM   5407 C CD1 . PHE B 1 511 ? 102.817 145.834 158.821 1.00 129.82 ? 511 PHE B CD1 1 
ATOM   5408 C CD2 . PHE B 1 511 ? 104.645 147.314 159.195 1.00 128.51 ? 511 PHE B CD2 1 
ATOM   5409 C CE1 . PHE B 1 511 ? 103.698 144.787 158.628 1.00 125.87 ? 511 PHE B CE1 1 
ATOM   5410 C CE2 . PHE B 1 511 ? 105.530 146.270 159.003 1.00 125.84 ? 511 PHE B CE2 1 
ATOM   5411 C CZ  . PHE B 1 511 ? 105.055 145.006 158.719 1.00 125.97 ? 511 PHE B CZ  1 
ATOM   5412 N N   . TYR B 1 512 ? 100.317 147.753 156.989 1.00 125.61 ? 512 TYR B N   1 
ATOM   5413 C CA  . TYR B 1 512 ? 99.744  146.985 155.890 1.00 126.83 ? 512 TYR B CA  1 
ATOM   5414 C C   . TYR B 1 512 ? 99.908  147.731 154.573 1.00 119.07 ? 512 TYR B C   1 
ATOM   5415 O O   . TYR B 1 512 ? 100.406 147.175 153.587 1.00 111.04 ? 512 TYR B O   1 
ATOM   5416 C CB  . TYR B 1 512 ? 98.270  146.686 156.168 1.00 130.92 ? 512 TYR B CB  1 
ATOM   5417 C CG  . TYR B 1 512 ? 98.043  145.697 157.291 1.00 133.72 ? 512 TYR B CG  1 
ATOM   5418 C CD1 . TYR B 1 512 ? 99.013  144.762 157.625 1.00 133.37 ? 512 TYR B CD1 1 
ATOM   5419 C CD2 . TYR B 1 512 ? 96.858  145.698 158.014 1.00 135.67 ? 512 TYR B CD2 1 
ATOM   5420 C CE1 . TYR B 1 512 ? 98.811  143.856 158.647 1.00 136.95 ? 512 TYR B CE1 1 
ATOM   5421 C CE2 . TYR B 1 512 ? 96.646  144.795 159.039 1.00 137.99 ? 512 TYR B CE2 1 
ATOM   5422 C CZ  . TYR B 1 512 ? 97.627  143.876 159.351 1.00 140.20 ? 512 TYR B CZ  1 
ATOM   5423 O OH  . TYR B 1 512 ? 97.423  142.975 160.370 1.00 142.14 ? 512 TYR B OH  1 
ATOM   5424 N N   . LEU B 1 513 ? 99.535  149.013 154.555 1.00 119.51 ? 513 LEU B N   1 
ATOM   5425 C CA  . LEU B 1 513 ? 99.794  149.830 153.376 1.00 112.97 ? 513 LEU B CA  1 
ATOM   5426 C C   . LEU B 1 513 ? 101.278 149.828 153.043 1.00 106.45 ? 513 LEU B C   1 
ATOM   5427 O O   . LEU B 1 513 ? 101.674 149.513 151.913 1.00 102.73 ? 513 LEU B O   1 
ATOM   5428 C CB  . LEU B 1 513 ? 99.288  151.256 153.593 1.00 111.92 ? 513 LEU B CB  1 
ATOM   5429 C CG  . LEU B 1 513 ? 97.880  151.566 153.081 1.00 111.76 ? 513 LEU B CG  1 
ATOM   5430 C CD1 . LEU B 1 513 ? 96.832  150.778 153.849 1.00 112.96 ? 513 LEU B CD1 1 
ATOM   5431 C CD2 . LEU B 1 513 ? 97.602  153.057 153.161 1.00 112.82 ? 513 LEU B CD2 1 
ATOM   5432 N N   . TRP B 1 514 ? 102.121 150.100 154.042 1.00 107.40 ? 514 TRP B N   1 
ATOM   5433 C CA  . TRP B 1 514 ? 103.557 150.107 153.801 1.00 104.72 ? 514 TRP B CA  1 
ATOM   5434 C C   . TRP B 1 514 ? 104.042 148.774 153.264 1.00 103.06 ? 514 TRP B C   1 
ATOM   5435 O O   . TRP B 1 514 ? 105.082 148.728 152.603 1.00 102.36 ? 514 TRP B O   1 
ATOM   5436 C CB  . TRP B 1 514 ? 104.323 150.450 155.077 1.00 107.67 ? 514 TRP B CB  1 
ATOM   5437 C CG  . TRP B 1 514 ? 105.802 150.441 154.870 1.00 103.32 ? 514 TRP B CG  1 
ATOM   5438 C CD1 . TRP B 1 514 ? 106.557 151.444 154.347 1.00 100.54 ? 514 TRP B CD1 1 
ATOM   5439 C CD2 . TRP B 1 514 ? 106.705 149.369 155.158 1.00 102.97 ? 514 TRP B CD2 1 
ATOM   5440 N NE1 . TRP B 1 514 ? 107.876 151.071 154.301 1.00 103.46 ? 514 TRP B NE1 1 
ATOM   5441 C CE2 . TRP B 1 514 ? 107.993 149.799 154.794 1.00 102.81 ? 514 TRP B CE2 1 
ATOM   5442 C CE3 . TRP B 1 514 ? 106.549 148.089 155.694 1.00 100.60 ? 514 TRP B CE3 1 
ATOM   5443 C CZ2 . TRP B 1 514 ? 109.118 148.997 154.947 1.00 99.28  ? 514 TRP B CZ2 1 
ATOM   5444 C CZ3 . TRP B 1 514 ? 107.667 147.294 155.845 1.00 98.23  ? 514 TRP B CZ3 1 
ATOM   5445 C CH2 . TRP B 1 514 ? 108.935 147.751 155.473 1.00 99.83  ? 514 TRP B CH2 1 
ATOM   5446 N N   . ILE B 1 515 ? 103.310 147.692 153.519 1.00 103.54 ? 515 ILE B N   1 
ATOM   5447 C CA  . ILE B 1 515 ? 103.678 146.412 152.931 1.00 102.92 ? 515 ILE B CA  1 
ATOM   5448 C C   . ILE B 1 515 ? 103.282 146.374 151.462 1.00 97.41  ? 515 ILE B C   1 
ATOM   5449 O O   . ILE B 1 515 ? 104.121 146.138 150.584 1.00 92.87  ? 515 ILE B O   1 
ATOM   5450 C CB  . ILE B 1 515 ? 103.047 145.251 153.716 1.00 105.73 ? 515 ILE B CB  1 
ATOM   5451 C CG1 . ILE B 1 515 ? 103.730 145.107 155.074 1.00 108.66 ? 515 ILE B CG1 1 
ATOM   5452 C CG2 . ILE B 1 515 ? 103.159 143.959 152.925 1.00 103.36 ? 515 ILE B CG2 1 
ATOM   5453 C CD1 . ILE B 1 515 ? 105.211 144.822 154.978 1.00 105.16 ? 515 ILE B CD1 1 
ATOM   5454 N N   . VAL B 1 516 ? 102.007 146.643 151.169 1.00 97.91  ? 516 VAL B N   1 
ATOM   5455 C CA  . VAL B 1 516 ? 101.495 146.350 149.831 1.00 95.87  ? 516 VAL B CA  1 
ATOM   5456 C C   . VAL B 1 516 ? 102.230 147.182 148.790 1.00 91.00  ? 516 VAL B C   1 
ATOM   5457 O O   . VAL B 1 516 ? 102.656 146.670 147.748 1.00 86.89  ? 516 VAL B O   1 
ATOM   5458 C CB  . VAL B 1 516 ? 99.970  146.558 149.766 1.00 97.56  ? 516 VAL B CB  1 
ATOM   5459 C CG1 . VAL B 1 516 ? 99.568  147.876 150.382 1.00 100.94 ? 516 VAL B CG1 1 
ATOM   5460 C CG2 . VAL B 1 516 ? 99.489  146.480 148.327 1.00 90.32  ? 516 VAL B CG2 1 
ATOM   5461 N N   . PHE B 1 517 ? 102.421 148.470 149.072 1.00 93.86  ? 517 PHE B N   1 
ATOM   5462 C CA  . PHE B 1 517 ? 103.192 149.308 148.163 1.00 89.21  ? 517 PHE B CA  1 
ATOM   5463 C C   . PHE B 1 517 ? 104.636 148.836 148.078 1.00 86.48  ? 517 PHE B C   1 
ATOM   5464 O O   . PHE B 1 517 ? 105.204 148.758 146.982 1.00 84.05  ? 517 PHE B O   1 
ATOM   5465 C CB  . PHE B 1 517 ? 103.101 150.768 148.598 1.00 87.45  ? 517 PHE B CB  1 
ATOM   5466 C CG  . PHE B 1 517 ? 101.775 151.396 148.289 1.00 89.09  ? 517 PHE B CG  1 
ATOM   5467 C CD1 . PHE B 1 517 ? 100.647 151.055 149.012 1.00 93.80  ? 517 PHE B CD1 1 
ATOM   5468 C CD2 . PHE B 1 517 ? 101.652 152.310 147.263 1.00 92.14  ? 517 PHE B CD2 1 
ATOM   5469 C CE1 . PHE B 1 517 ? 99.425  151.618 148.721 1.00 100.94 ? 517 PHE B CE1 1 
ATOM   5470 C CE2 . PHE B 1 517 ? 100.433 152.882 146.971 1.00 97.01  ? 517 PHE B CE2 1 
ATOM   5471 C CZ  . PHE B 1 517 ? 99.318  152.535 147.701 1.00 103.44 ? 517 PHE B CZ  1 
ATOM   5472 N N   . TYR B 1 518 ? 105.236 148.474 149.218 1.00 87.56  ? 518 TYR B N   1 
ATOM   5473 C CA  . TYR B 1 518 ? 106.558 147.858 149.177 1.00 83.26  ? 518 TYR B CA  1 
ATOM   5474 C C   . TYR B 1 518 ? 106.547 146.607 148.319 1.00 83.57  ? 518 TYR B C   1 
ATOM   5475 O O   . TYR B 1 518 ? 107.562 146.267 147.706 1.00 83.66  ? 518 TYR B O   1 
ATOM   5476 C CB  . TYR B 1 518 ? 107.047 147.519 150.582 1.00 87.50  ? 518 TYR B CB  1 
ATOM   5477 C CG  . TYR B 1 518 ? 108.183 146.521 150.603 1.00 84.59  ? 518 TYR B CG  1 
ATOM   5478 C CD1 . TYR B 1 518 ? 107.954 145.184 150.892 1.00 85.14  ? 518 TYR B CD1 1 
ATOM   5479 C CD2 . TYR B 1 518 ? 109.482 146.914 150.324 1.00 85.46  ? 518 TYR B CD2 1 
ATOM   5480 C CE1 . TYR B 1 518 ? 108.988 144.270 150.909 1.00 85.31  ? 518 TYR B CE1 1 
ATOM   5481 C CE2 . TYR B 1 518 ? 110.521 146.009 150.341 1.00 83.68  ? 518 TYR B CE2 1 
ATOM   5482 C CZ  . TYR B 1 518 ? 110.269 144.689 150.634 1.00 85.92  ? 518 TYR B CZ  1 
ATOM   5483 O OH  . TYR B 1 518 ? 111.300 143.779 150.651 1.00 91.85  ? 518 TYR B OH  1 
ATOM   5484 N N   . ILE B 1 519 ? 105.417 145.906 148.269 1.00 84.09  ? 519 ILE B N   1 
ATOM   5485 C CA  . ILE B 1 519 ? 105.257 144.852 147.278 1.00 82.96  ? 519 ILE B CA  1 
ATOM   5486 C C   . ILE B 1 519 ? 105.108 145.462 145.892 1.00 83.91  ? 519 ILE B C   1 
ATOM   5487 O O   . ILE B 1 519 ? 105.914 145.201 144.989 1.00 82.38  ? 519 ILE B O   1 
ATOM   5488 C CB  . ILE B 1 519 ? 104.057 143.958 147.630 1.00 81.76  ? 519 ILE B CB  1 
ATOM   5489 C CG1 . ILE B 1 519 ? 104.263 143.305 148.994 1.00 82.16  ? 519 ILE B CG1 1 
ATOM   5490 C CG2 . ILE B 1 519 ? 103.860 142.900 146.563 1.00 86.25  ? 519 ILE B CG2 1 
ATOM   5491 C CD1 . ILE B 1 519 ? 105.441 142.368 149.041 1.00 78.19  ? 519 ILE B CD1 1 
ATOM   5492 N N   . ILE B 1 520 ? 104.111 146.338 145.727 1.00 83.96  ? 520 ILE B N   1 
ATOM   5493 C CA  . ILE B 1 520 ? 103.726 146.792 144.393 1.00 78.83  ? 520 ILE B CA  1 
ATOM   5494 C C   . ILE B 1 520 ? 104.910 147.438 143.692 1.00 77.39  ? 520 ILE B C   1 
ATOM   5495 O O   . ILE B 1 520 ? 105.288 147.045 142.581 1.00 76.24  ? 520 ILE B O   1 
ATOM   5496 C CB  . ILE B 1 520 ? 102.531 147.757 144.478 1.00 77.63  ? 520 ILE B CB  1 
ATOM   5497 C CG1 . ILE B 1 520 ? 101.270 147.016 144.921 1.00 79.40  ? 520 ILE B CG1 1 
ATOM   5498 C CG2 . ILE B 1 520 ? 102.299 148.428 143.139 1.00 80.45  ? 520 ILE B CG2 1 
ATOM   5499 C CD1 . ILE B 1 520 ? 100.770 146.010 143.911 1.00 85.03  ? 520 ILE B CD1 1 
ATOM   5500 N N   . SER B 1 521 ? 105.552 148.399 144.359 1.00 76.42  ? 521 SER B N   1 
ATOM   5501 C CA  . SER B 1 521 ? 106.726 149.034 143.778 1.00 70.87  ? 521 SER B CA  1 
ATOM   5502 C C   . SER B 1 521 ? 107.796 148.000 143.466 1.00 70.11  ? 521 SER B C   1 
ATOM   5503 O O   . SER B 1 521 ? 108.309 147.945 142.342 1.00 70.43  ? 521 SER B O   1 
ATOM   5504 C CB  . SER B 1 521 ? 107.269 150.103 144.722 1.00 73.27  ? 521 SER B CB  1 
ATOM   5505 O OG  . SER B 1 521 ? 108.376 150.772 144.146 1.00 75.05  ? 521 SER B OG  1 
ATOM   5506 N N   . SER B 1 522 ? 108.098 147.124 144.430 1.00 73.12  ? 522 SER B N   1 
ATOM   5507 C CA  . SER B 1 522 ? 109.137 146.128 144.204 1.00 70.23  ? 522 SER B CA  1 
ATOM   5508 C C   . SER B 1 522 ? 108.791 145.206 143.053 1.00 72.01  ? 522 SER B C   1 
ATOM   5509 O O   . SER B 1 522 ? 109.689 144.579 142.484 1.00 74.37  ? 522 SER B O   1 
ATOM   5510 C CB  . SER B 1 522 ? 109.383 145.302 145.462 1.00 72.56  ? 522 SER B CB  1 
ATOM   5511 O OG  . SER B 1 522 ? 109.912 146.100 146.502 1.00 79.98  ? 522 SER B OG  1 
ATOM   5512 N N   . CYS B 1 523 ? 107.514 145.108 142.694 1.00 71.53  ? 523 CYS B N   1 
ATOM   5513 C CA  . CYS B 1 523 ? 107.160 144.400 141.476 1.00 74.43  ? 523 CYS B CA  1 
ATOM   5514 C C   . CYS B 1 523 ? 107.086 145.345 140.288 1.00 74.85  ? 523 CYS B C   1 
ATOM   5515 O O   . CYS B 1 523 ? 107.599 145.022 139.211 1.00 69.94  ? 523 CYS B O   1 
ATOM   5516 C CB  . CYS B 1 523 ? 105.830 143.669 141.660 1.00 74.98  ? 523 CYS B CB  1 
ATOM   5517 S SG  . CYS B 1 523 ? 105.871 142.404 142.943 1.00 90.00  ? 523 CYS B SG  1 
ATOM   5518 N N   . TYR B 1 524 ? 106.503 146.532 140.489 1.00 75.14  ? 524 TYR B N   1 
ATOM   5519 C CA  . TYR B 1 524 ? 106.298 147.465 139.385 1.00 68.73  ? 524 TYR B CA  1 
ATOM   5520 C C   . TYR B 1 524 ? 107.620 147.823 138.727 1.00 69.89  ? 524 TYR B C   1 
ATOM   5521 O O   . TYR B 1 524 ? 107.728 147.835 137.495 1.00 71.59  ? 524 TYR B O   1 
ATOM   5522 C CB  . TYR B 1 524 ? 105.590 148.720 139.895 1.00 67.69  ? 524 TYR B CB  1 
ATOM   5523 C CG  . TYR B 1 524 ? 104.881 149.543 138.839 1.00 65.83  ? 524 TYR B CG  1 
ATOM   5524 C CD1 . TYR B 1 524 ? 105.116 149.344 137.487 1.00 61.95  ? 524 TYR B CD1 1 
ATOM   5525 C CD2 . TYR B 1 524 ? 103.971 150.522 139.204 1.00 68.47  ? 524 TYR B CD2 1 
ATOM   5526 C CE1 . TYR B 1 524 ? 104.471 150.096 136.536 1.00 63.25  ? 524 TYR B CE1 1 
ATOM   5527 C CE2 . TYR B 1 524 ? 103.321 151.276 138.260 1.00 67.97  ? 524 TYR B CE2 1 
ATOM   5528 C CZ  . TYR B 1 524 ? 103.575 151.061 136.930 1.00 67.04  ? 524 TYR B CZ  1 
ATOM   5529 O OH  . TYR B 1 524 ? 102.922 151.821 135.996 1.00 72.00  ? 524 TYR B OH  1 
ATOM   5530 N N   . THR B 1 525 ? 108.641 148.108 139.531 1.00 69.69  ? 525 THR B N   1 
ATOM   5531 C CA  . THR B 1 525 ? 109.972 148.312 138.978 1.00 63.43  ? 525 THR B CA  1 
ATOM   5532 C C   . THR B 1 525 ? 110.509 147.024 138.374 1.00 67.39  ? 525 THR B C   1 
ATOM   5533 O O   . THR B 1 525 ? 110.981 147.012 137.230 1.00 70.14  ? 525 THR B O   1 
ATOM   5534 C CB  . THR B 1 525 ? 110.911 148.816 140.065 1.00 62.77  ? 525 THR B CB  1 
ATOM   5535 O OG1 . THR B 1 525 ? 111.132 147.766 141.010 1.00 66.33  ? 525 THR B OG1 1 
ATOM   5536 C CG2 . THR B 1 525 ? 110.289 149.992 140.785 1.00 68.55  ? 525 THR B CG2 1 
ATOM   5537 N N   . LEU B 1 526 ? 110.403 145.918 139.118 1.00 67.14  ? 526 LEU B N   1 
ATOM   5538 C CA  . LEU B 1 526 ? 111.101 144.692 138.739 1.00 68.28  ? 526 LEU B CA  1 
ATOM   5539 C C   . LEU B 1 526 ? 110.674 144.220 137.360 1.00 72.08  ? 526 LEU B C   1 
ATOM   5540 O O   . LEU B 1 526 ? 111.510 144.046 136.464 1.00 72.59  ? 526 LEU B O   1 
ATOM   5541 C CB  . LEU B 1 526 ? 110.845 143.605 139.781 1.00 62.31  ? 526 LEU B CB  1 
ATOM   5542 C CG  . LEU B 1 526 ? 111.220 142.176 139.394 1.00 64.63  ? 526 LEU B CG  1 
ATOM   5543 C CD1 . LEU B 1 526 ? 112.686 142.082 139.021 1.00 69.51  ? 526 LEU B CD1 1 
ATOM   5544 C CD2 . LEU B 1 526 ? 110.894 141.222 140.528 1.00 69.19  ? 526 LEU B CD2 1 
ATOM   5545 N N   . ILE B 1 527 ? 109.365 144.063 137.155 1.00 71.85  ? 527 ILE B N   1 
ATOM   5546 C CA  . ILE B 1 527 ? 108.865 143.627 135.857 1.00 71.32  ? 527 ILE B CA  1 
ATOM   5547 C C   . ILE B 1 527 ? 109.346 144.575 134.775 1.00 71.99  ? 527 ILE B C   1 
ATOM   5548 O O   . ILE B 1 527 ? 109.762 144.147 133.691 1.00 69.53  ? 527 ILE B O   1 
ATOM   5549 C CB  . ILE B 1 527 ? 107.331 143.533 135.881 1.00 65.08  ? 527 ILE B CB  1 
ATOM   5550 C CG1 . ILE B 1 527 ? 106.867 142.789 137.131 1.00 67.45  ? 527 ILE B CG1 1 
ATOM   5551 C CG2 . ILE B 1 527 ? 106.831 142.838 134.632 1.00 65.17  ? 527 ILE B CG2 1 
ATOM   5552 C CD1 . ILE B 1 527 ? 105.391 142.914 137.393 1.00 69.84  ? 527 ILE B CD1 1 
ATOM   5553 N N   . TRP B 1 528 ? 109.332 145.877 135.070 1.00 74.15  ? 528 TRP B N   1 
ATOM   5554 C CA  . TRP B 1 528 ? 109.831 146.863 134.122 1.00 70.83  ? 528 TRP B CA  1 
ATOM   5555 C C   . TRP B 1 528 ? 111.247 146.519 133.686 1.00 72.63  ? 528 TRP B C   1 
ATOM   5556 O O   . TRP B 1 528 ? 111.524 146.381 132.489 1.00 76.16  ? 528 TRP B O   1 
ATOM   5557 C CB  . TRP B 1 528 ? 109.780 148.254 134.751 1.00 67.15  ? 528 TRP B CB  1 
ATOM   5558 C CG  . TRP B 1 528 ? 109.717 149.346 133.753 1.00 66.61  ? 528 TRP B CG  1 
ATOM   5559 C CD1 . TRP B 1 528 ? 110.764 150.043 133.230 1.00 72.46  ? 528 TRP B CD1 1 
ATOM   5560 C CD2 . TRP B 1 528 ? 108.539 149.875 133.146 1.00 68.21  ? 528 TRP B CD2 1 
ATOM   5561 N NE1 . TRP B 1 528 ? 110.310 150.975 132.332 1.00 73.96  ? 528 TRP B NE1 1 
ATOM   5562 C CE2 . TRP B 1 528 ? 108.945 150.891 132.264 1.00 73.90  ? 528 TRP B CE2 1 
ATOM   5563 C CE3 . TRP B 1 528 ? 107.179 149.587 133.263 1.00 69.30  ? 528 TRP B CE3 1 
ATOM   5564 C CZ2 . TRP B 1 528 ? 108.040 151.618 131.501 1.00 77.54  ? 528 TRP B CZ2 1 
ATOM   5565 C CZ3 . TRP B 1 528 ? 106.286 150.307 132.508 1.00 69.66  ? 528 TRP B CZ3 1 
ATOM   5566 C CH2 . TRP B 1 528 ? 106.717 151.313 131.640 1.00 74.63  ? 528 TRP B CH2 1 
ATOM   5567 N N   . ASP B 1 529 ? 112.140 146.304 134.658 1.00 69.79  ? 529 ASP B N   1 
ATOM   5568 C CA  . ASP B 1 529 ? 113.519 145.965 134.326 1.00 70.04  ? 529 ASP B CA  1 
ATOM   5569 C C   . ASP B 1 529 ? 113.588 144.741 133.434 1.00 75.09  ? 529 ASP B C   1 
ATOM   5570 O O   . ASP B 1 529 ? 114.447 144.666 132.549 1.00 75.44  ? 529 ASP B O   1 
ATOM   5571 C CB  . ASP B 1 529 ? 114.330 145.711 135.593 1.00 73.73  ? 529 ASP B CB  1 
ATOM   5572 C CG  . ASP B 1 529 ? 114.459 146.936 136.456 1.00 77.41  ? 529 ASP B CG  1 
ATOM   5573 O OD1 . ASP B 1 529 ? 113.939 148.000 136.060 1.00 77.72  ? 529 ASP B OD1 1 
ATOM   5574 O OD2 . ASP B 1 529 ? 115.083 146.836 137.533 1.00 73.71  ? 529 ASP B OD2 1 
ATOM   5575 N N   . LEU B 1 530 ? 112.692 143.781 133.639 1.00 74.80  ? 530 LEU B N   1 
ATOM   5576 C CA  . LEU B 1 530 ? 112.740 142.545 132.878 1.00 74.13  ? 530 LEU B CA  1 
ATOM   5577 C C   . LEU B 1 530 ? 111.926 142.607 131.595 1.00 76.33  ? 530 LEU B C   1 
ATOM   5578 O O   . LEU B 1 530 ? 112.045 141.701 130.766 1.00 79.52  ? 530 LEU B O   1 
ATOM   5579 C CB  . LEU B 1 530 ? 112.255 141.381 133.745 1.00 74.69  ? 530 LEU B CB  1 
ATOM   5580 C CG  . LEU B 1 530 ? 112.975 141.229 135.083 1.00 71.13  ? 530 LEU B CG  1 
ATOM   5581 C CD1 . LEU B 1 530 ? 112.371 140.101 135.900 1.00 76.59  ? 530 LEU B CD1 1 
ATOM   5582 C CD2 . LEU B 1 530 ? 114.451 140.992 134.856 1.00 66.83  ? 530 LEU B CD2 1 
ATOM   5583 N N   . LYS B 1 531 ? 111.125 143.648 131.397 1.00 74.48  ? 531 LYS B N   1 
ATOM   5584 C CA  . LYS B 1 531 ? 110.310 143.715 130.192 1.00 74.73  ? 531 LYS B CA  1 
ATOM   5585 C C   . LYS B 1 531 ? 110.499 144.999 129.406 1.00 75.57  ? 531 LYS B C   1 
ATOM   5586 O O   . LYS B 1 531 ? 110.489 144.966 128.173 1.00 78.36  ? 531 LYS B O   1 
ATOM   5587 C CB  . LYS B 1 531 ? 108.827 143.542 130.539 1.00 68.59  ? 531 LYS B CB  1 
ATOM   5588 C CG  . LYS B 1 531 ? 108.430 142.115 130.863 1.00 68.93  ? 531 LYS B CG  1 
ATOM   5589 C CD  . LYS B 1 531 ? 106.921 141.967 130.941 1.00 74.52  ? 531 LYS B CD  1 
ATOM   5590 C CE  . LYS B 1 531 ? 106.516 140.513 131.124 1.00 75.75  ? 531 LYS B CE  1 
ATOM   5591 N NZ  . LYS B 1 531 ? 105.035 140.349 131.147 1.00 76.54  ? 531 LYS B NZ  1 
ATOM   5592 N N   . MET B 1 532 ? 110.676 146.129 130.080 1.00 70.46  ? 532 MET B N   1 
ATOM   5593 C CA  . MET B 1 532 ? 110.852 147.406 129.404 1.00 71.24  ? 532 MET B CA  1 
ATOM   5594 C C   . MET B 1 532 ? 112.309 147.832 129.309 1.00 75.41  ? 532 MET B C   1 
ATOM   5595 O O   . MET B 1 532 ? 112.737 148.318 128.259 1.00 81.62  ? 532 MET B O   1 
ATOM   5596 C CB  . MET B 1 532 ? 110.044 148.492 130.115 1.00 70.24  ? 532 MET B CB  1 
ATOM   5597 C CG  . MET B 1 532 ? 108.549 148.243 130.099 1.00 72.07  ? 532 MET B CG  1 
ATOM   5598 S SD  . MET B 1 532 ? 107.888 148.199 128.426 1.00 84.99  ? 532 MET B SD  1 
ATOM   5599 C CE  . MET B 1 532 ? 108.306 149.844 127.859 1.00 73.95  ? 532 MET B CE  1 
ATOM   5600 N N   . ASP B 1 533 ? 113.087 147.660 130.377 1.00 70.57  ? 533 ASP B N   1 
ATOM   5601 C CA  . ASP B 1 533 ? 114.495 148.033 130.327 1.00 65.05  ? 533 ASP B CA  1 
ATOM   5602 C C   . ASP B 1 533 ? 115.303 147.018 129.530 1.00 68.28  ? 533 ASP B C   1 
ATOM   5603 O O   . ASP B 1 533 ? 115.776 147.309 128.427 1.00 70.37  ? 533 ASP B O   1 
ATOM   5604 C CB  . ASP B 1 533 ? 115.059 148.162 131.744 1.00 67.22  ? 533 ASP B CB  1 
ATOM   5605 C CG  . ASP B 1 533 ? 114.596 149.420 132.447 1.00 76.81  ? 533 ASP B CG  1 
ATOM   5606 O OD1 . ASP B 1 533 ? 114.388 150.441 131.760 1.00 81.97  ? 533 ASP B OD1 1 
ATOM   5607 O OD2 . ASP B 1 533 ? 114.453 149.394 133.687 1.00 73.56  ? 533 ASP B OD2 1 
ATOM   5608 N N   . TRP B 1 534 ? 115.447 145.809 130.065 1.00 69.62  ? 534 TRP B N   1 
ATOM   5609 C CA  . TRP B 1 534 ? 116.261 144.795 129.415 1.00 66.76  ? 534 TRP B CA  1 
ATOM   5610 C C   . TRP B 1 534 ? 115.560 144.162 128.227 1.00 75.60  ? 534 TRP B C   1 
ATOM   5611 O O   . TRP B 1 534 ? 116.232 143.655 127.326 1.00 78.78  ? 534 TRP B O   1 
ATOM   5612 C CB  . TRP B 1 534 ? 116.646 143.700 130.413 1.00 67.66  ? 534 TRP B CB  1 
ATOM   5613 C CG  . TRP B 1 534 ? 117.299 144.202 131.667 1.00 64.99  ? 534 TRP B CG  1 
ATOM   5614 C CD1 . TRP B 1 534 ? 117.690 145.479 131.936 1.00 66.06  ? 534 TRP B CD1 1 
ATOM   5615 C CD2 . TRP B 1 534 ? 117.632 143.432 132.825 1.00 61.29  ? 534 TRP B CD2 1 
ATOM   5616 N NE1 . TRP B 1 534 ? 118.244 145.551 133.186 1.00 61.92  ? 534 TRP B NE1 1 
ATOM   5617 C CE2 . TRP B 1 534 ? 118.219 144.307 133.753 1.00 57.51  ? 534 TRP B CE2 1 
ATOM   5618 C CE3 . TRP B 1 534 ? 117.490 142.087 133.165 1.00 65.23  ? 534 TRP B CE3 1 
ATOM   5619 C CZ2 . TRP B 1 534 ? 118.666 143.883 134.995 1.00 56.99  ? 534 TRP B CZ2 1 
ATOM   5620 C CZ3 . TRP B 1 534 ? 117.931 141.670 134.400 1.00 64.42  ? 534 TRP B CZ3 1 
ATOM   5621 C CH2 . TRP B 1 534 ? 118.512 142.564 135.300 1.00 60.70  ? 534 TRP B CH2 1 
ATOM   5622 N N   . GLY B 1 535 ? 114.234 144.190 128.196 1.00 81.45  ? 535 GLY B N   1 
ATOM   5623 C CA  . GLY B 1 535 ? 113.499 143.508 127.148 1.00 83.14  ? 535 GLY B CA  1 
ATOM   5624 C C   . GLY B 1 535 ? 113.619 142.003 127.213 1.00 86.17  ? 535 GLY B C   1 
ATOM   5625 O O   . GLY B 1 535 ? 113.747 141.350 126.170 1.00 92.63  ? 535 GLY B O   1 
ATOM   5626 N N   . LEU B 1 536 ? 113.587 141.434 128.414 1.00 84.22  ? 536 LEU B N   1 
ATOM   5627 C CA  . LEU B 1 536 ? 113.650 139.994 128.581 1.00 91.21  ? 536 LEU B CA  1 
ATOM   5628 C C   . LEU B 1 536 ? 112.240 139.406 128.589 1.00 94.12  ? 536 LEU B C   1 
ATOM   5629 O O   . LEU B 1 536 ? 111.242 140.118 128.462 1.00 92.90  ? 536 LEU B O   1 
ATOM   5630 C CB  . LEU B 1 536 ? 114.411 139.635 129.856 1.00 90.01  ? 536 LEU B CB  1 
ATOM   5631 C CG  . LEU B 1 536 ? 115.911 139.925 129.822 1.00 85.18  ? 536 LEU B CG  1 
ATOM   5632 C CD1 . LEU B 1 536 ? 116.593 139.385 131.061 1.00 78.56  ? 536 LEU B CD1 1 
ATOM   5633 C CD2 . LEU B 1 536 ? 116.536 139.341 128.570 1.00 84.97  ? 536 LEU B CD2 1 
ATOM   5634 N N   . PHE B 1 537 ? 112.161 138.082 128.735 1.00 94.14  ? 537 PHE B N   1 
ATOM   5635 C CA  . PHE B 1 537 ? 110.891 137.357 128.700 1.00 94.20  ? 537 PHE B CA  1 
ATOM   5636 C C   . PHE B 1 537 ? 110.126 137.653 127.415 1.00 97.30  ? 537 PHE B C   1 
ATOM   5637 O O   . PHE B 1 537 ? 108.898 137.755 127.404 1.00 101.17 ? 537 PHE B O   1 
ATOM   5638 C CB  . PHE B 1 537 ? 110.032 137.676 129.922 1.00 92.13  ? 537 PHE B CB  1 
ATOM   5639 C CG  . PHE B 1 537 ? 110.597 137.171 131.211 1.00 90.42  ? 537 PHE B CG  1 
ATOM   5640 C CD1 . PHE B 1 537 ? 110.728 135.816 131.440 1.00 97.16  ? 537 PHE B CD1 1 
ATOM   5641 C CD2 . PHE B 1 537 ? 110.978 138.050 132.205 1.00 83.67  ? 537 PHE B CD2 1 
ATOM   5642 C CE1 . PHE B 1 537 ? 111.242 135.349 132.631 1.00 93.58  ? 537 PHE B CE1 1 
ATOM   5643 C CE2 . PHE B 1 537 ? 111.490 137.589 133.397 1.00 82.24  ? 537 PHE B CE2 1 
ATOM   5644 C CZ  . PHE B 1 537 ? 111.622 136.237 133.610 1.00 84.80  ? 537 PHE B CZ  1 
ATOM   5645 N N   . ASP B 1 538 ? 110.861 137.795 126.318 1.00 100.31 ? 538 ASP B N   1 
ATOM   5646 C CA  . ASP B 1 538 ? 110.250 138.095 125.032 1.00 109.23 ? 538 ASP B CA  1 
ATOM   5647 C C   . ASP B 1 538 ? 109.793 136.801 124.373 1.00 116.82 ? 538 ASP B C   1 
ATOM   5648 O O   . ASP B 1 538 ? 110.619 135.962 123.999 1.00 114.80 ? 538 ASP B O   1 
ATOM   5649 C CB  . ASP B 1 538 ? 111.233 138.840 124.134 1.00 107.51 ? 538 ASP B CB  1 
ATOM   5650 C CG  . ASP B 1 538 ? 110.579 139.382 122.885 1.00 114.96 ? 538 ASP B CG  1 
ATOM   5651 O OD1 . ASP B 1 538 ? 109.881 140.413 122.980 1.00 114.64 ? 538 ASP B OD1 1 
ATOM   5652 O OD2 . ASP B 1 538 ? 110.757 138.776 121.810 1.00 119.92 ? 538 ASP B OD2 1 
ATOM   5653 N N   . LYS B 1 539 ? 108.482 136.639 124.235 1.00 119.06 ? 539 LYS B N   1 
ATOM   5654 C CA  . LYS B 1 539 ? 107.946 135.444 123.609 1.00 120.20 ? 539 LYS B CA  1 
ATOM   5655 C C   . LYS B 1 539 ? 108.252 135.448 122.115 1.00 124.85 ? 539 LYS B C   1 
ATOM   5656 O O   . LYS B 1 539 ? 108.557 136.484 121.518 1.00 122.70 ? 539 LYS B O   1 
ATOM   5657 C CB  . LYS B 1 539 ? 106.442 135.342 123.852 1.00 118.90 ? 539 LYS B CB  1 
ATOM   5658 C CG  . LYS B 1 539 ? 106.070 135.372 125.325 1.00 123.40 ? 539 LYS B CG  1 
ATOM   5659 C CD  . LYS B 1 539 ? 104.576 135.222 125.534 1.00 127.05 ? 539 LYS B CD  1 
ATOM   5660 C CE  . LYS B 1 539 ? 104.230 135.292 127.012 1.00 124.99 ? 539 LYS B CE  1 
ATOM   5661 N NZ  . LYS B 1 539 ? 105.003 134.294 127.801 1.00 114.40 ? 539 LYS B NZ  1 
ATOM   5662 N N   . ASN B 1 540 ? 108.180 134.258 121.518 1.00 128.99 ? 540 ASN B N   1 
ATOM   5663 C CA  . ASN B 1 540 ? 108.569 134.043 120.124 1.00 125.75 ? 540 ASN B CA  1 
ATOM   5664 C C   . ASN B 1 540 ? 110.025 134.434 119.887 1.00 123.59 ? 540 ASN B C   1 
ATOM   5665 O O   . ASN B 1 540 ? 110.393 134.873 118.795 1.00 124.22 ? 540 ASN B O   1 
ATOM   5666 C CB  . ASN B 1 540 ? 107.644 134.792 119.160 1.00 126.67 ? 540 ASN B CB  1 
ATOM   5667 C CG  . ASN B 1 540 ? 106.202 134.331 119.261 1.00 128.63 ? 540 ASN B CG  1 
ATOM   5668 O OD1 . ASN B 1 540 ? 105.928 133.178 119.593 1.00 127.61 ? 540 ASN B OD1 1 
ATOM   5669 N ND2 . ASN B 1 540 ? 105.271 135.234 118.972 1.00 128.35 ? 540 ASN B ND2 1 
ATOM   5670 N N   . ALA B 1 541 ? 110.858 134.284 120.919 1.00 123.91 ? 541 ALA B N   1 
ATOM   5671 C CA  . ALA B 1 541 ? 112.278 134.590 120.783 1.00 123.99 ? 541 ALA B CA  1 
ATOM   5672 C C   . ALA B 1 541 ? 112.973 133.607 119.849 1.00 125.21 ? 541 ALA B C   1 
ATOM   5673 O O   . ALA B 1 541 ? 113.819 134.003 119.039 1.00 121.23 ? 541 ALA B O   1 
ATOM   5674 C CB  . ALA B 1 541 ? 112.946 134.591 122.156 1.00 120.18 ? 541 ALA B CB  1 
ATOM   5675 N N   . GLY B 1 542 ? 112.633 132.326 119.946 1.00 128.23 ? 542 GLY B N   1 
ATOM   5676 C CA  . GLY B 1 542 ? 113.283 131.311 119.142 1.00 127.17 ? 542 GLY B CA  1 
ATOM   5677 C C   . GLY B 1 542 ? 113.893 130.211 119.984 1.00 128.99 ? 542 GLY B C   1 
ATOM   5678 O O   . GLY B 1 542 ? 113.198 129.585 120.789 1.00 128.30 ? 542 GLY B O   1 
ATOM   5679 N N   . GLU B 1 543 ? 115.190 129.965 119.812 1.00 130.24 ? 543 GLU B N   1 
ATOM   5680 C CA  . GLU B 1 543 ? 115.876 128.934 120.578 1.00 130.09 ? 543 GLU B CA  1 
ATOM   5681 C C   . GLU B 1 543 ? 116.309 129.403 121.961 1.00 125.67 ? 543 GLU B C   1 
ATOM   5682 O O   . GLU B 1 543 ? 116.639 128.564 122.806 1.00 121.32 ? 543 GLU B O   1 
ATOM   5683 C CB  . GLU B 1 543 ? 117.100 128.429 119.805 1.00 132.47 ? 543 GLU B CB  1 
ATOM   5684 C CG  . GLU B 1 543 ? 116.770 127.784 118.465 1.00 134.81 ? 543 GLU B CG  1 
ATOM   5685 C CD  . GLU B 1 543 ? 116.020 126.471 118.611 1.00 133.96 ? 543 GLU B CD  1 
ATOM   5686 O OE1 . GLU B 1 543 ? 116.065 125.872 119.705 1.00 129.91 ? 543 GLU B OE1 1 
ATOM   5687 O OE2 . GLU B 1 543 ? 115.384 126.036 117.628 1.00 137.91 ? 543 GLU B OE2 1 
ATOM   5688 N N   . ASN B 1 544 ? 116.312 130.708 122.215 1.00 125.81 ? 544 ASN B N   1 
ATOM   5689 C CA  . ASN B 1 544 ? 116.670 131.226 123.527 1.00 121.52 ? 544 ASN B CA  1 
ATOM   5690 C C   . ASN B 1 544 ? 115.512 131.019 124.493 1.00 117.32 ? 544 ASN B C   1 
ATOM   5691 O O   . ASN B 1 544 ? 114.345 131.159 124.115 1.00 118.54 ? 544 ASN B O   1 
ATOM   5692 C CB  . ASN B 1 544 ? 117.036 132.706 123.436 1.00 117.61 ? 544 ASN B CB  1 
ATOM   5693 C CG  . ASN B 1 544 ? 118.236 132.951 122.547 1.00 113.23 ? 544 ASN B CG  1 
ATOM   5694 O OD1 . ASN B 1 544 ? 119.172 132.155 122.518 1.00 111.23 ? 544 ASN B OD1 1 
ATOM   5695 N ND2 . ASN B 1 544 ? 118.211 134.054 121.809 1.00 109.25 ? 544 ASN B ND2 1 
ATOM   5696 N N   . THR B 1 545 ? 115.833 130.677 125.738 1.00 112.73 ? 545 THR B N   1 
ATOM   5697 C CA  . THR B 1 545 ? 114.808 130.345 126.725 1.00 109.59 ? 545 THR B CA  1 
ATOM   5698 C C   . THR B 1 545 ? 114.402 131.611 127.468 1.00 104.36 ? 545 THR B C   1 
ATOM   5699 O O   . THR B 1 545 ? 114.999 131.989 128.478 1.00 100.49 ? 545 THR B O   1 
ATOM   5700 C CB  . THR B 1 545 ? 115.306 129.272 127.684 1.00 106.79 ? 545 THR B CB  1 
ATOM   5701 O OG1 . THR B 1 545 ? 115.798 128.154 126.936 1.00 109.47 ? 545 THR B OG1 1 
ATOM   5702 C CG2 . THR B 1 545 ? 114.174 128.804 128.587 1.00 104.91 ? 545 THR B CG2 1 
ATOM   5703 N N   . PHE B 1 546 ? 113.368 132.273 126.949 1.00 104.98 ? 546 PHE B N   1 
ATOM   5704 C CA  . PHE B 1 546 ? 112.692 133.370 127.639 1.00 105.55 ? 546 PHE B CA  1 
ATOM   5705 C C   . PHE B 1 546 ? 113.606 134.566 127.897 1.00 105.29 ? 546 PHE B C   1 
ATOM   5706 O O   . PHE B 1 546 ? 113.497 135.217 128.938 1.00 103.84 ? 546 PHE B O   1 
ATOM   5707 C CB  . PHE B 1 546 ? 112.078 132.891 128.959 1.00 108.32 ? 546 PHE B CB  1 
ATOM   5708 C CG  . PHE B 1 546 ? 110.646 132.458 128.844 1.00 114.77 ? 546 PHE B CG  1 
ATOM   5709 C CD1 . PHE B 1 546 ? 109.787 133.080 127.954 1.00 113.97 ? 546 PHE B CD1 1 
ATOM   5710 C CD2 . PHE B 1 546 ? 110.155 131.432 129.634 1.00 116.34 ? 546 PHE B CD2 1 
ATOM   5711 C CE1 . PHE B 1 546 ? 108.465 132.684 127.851 1.00 119.01 ? 546 PHE B CE1 1 
ATOM   5712 C CE2 . PHE B 1 546 ? 108.836 131.031 129.534 1.00 117.92 ? 546 PHE B CE2 1 
ATOM   5713 C CZ  . PHE B 1 546 ? 107.991 131.659 128.642 1.00 121.31 ? 546 PHE B CZ  1 
ATOM   5714 N N   . LEU B 1 547 ? 114.520 134.880 126.978 1.00 104.78 ? 547 LEU B N   1 
ATOM   5715 C CA  . LEU B 1 547 ? 115.314 136.099 127.092 1.00 97.91  ? 547 LEU B CA  1 
ATOM   5716 C C   . LEU B 1 547 ? 115.022 137.068 125.949 1.00 98.25  ? 547 LEU B C   1 
ATOM   5717 O O   . LEU B 1 547 ? 114.474 138.144 126.190 1.00 95.40  ? 547 LEU B O   1 
ATOM   5718 C CB  . LEU B 1 547 ? 116.804 135.758 127.143 1.00 97.70  ? 547 LEU B CB  1 
ATOM   5719 C CG  . LEU B 1 547 ? 117.239 134.745 128.199 1.00 94.62  ? 547 LEU B CG  1 
ATOM   5720 C CD1 . LEU B 1 547 ? 118.746 134.563 128.183 1.00 89.88  ? 547 LEU B CD1 1 
ATOM   5721 C CD2 . LEU B 1 547 ? 116.767 135.180 129.564 1.00 90.62  ? 547 LEU B CD2 1 
ATOM   5722 N N   . ARG B 1 548 ? 115.326 136.692 124.706 1.00 100.68 ? 548 ARG B N   1 
ATOM   5723 C CA  . ARG B 1 548 ? 115.122 137.555 123.545 1.00 99.12  ? 548 ARG B CA  1 
ATOM   5724 C C   . ARG B 1 548 ? 115.593 136.862 122.274 1.00 104.89 ? 548 ARG B C   1 
ATOM   5725 O O   . ARG B 1 548 ? 116.130 135.752 122.330 1.00 106.10 ? 548 ARG B O   1 
ATOM   5726 C CB  . ARG B 1 548 ? 115.850 138.892 123.705 1.00 95.25  ? 548 ARG B CB  1 
ATOM   5727 C CG  . ARG B 1 548 ? 117.347 138.776 123.854 1.00 93.28  ? 548 ARG B CG  1 
ATOM   5728 C CD  . ARG B 1 548 ? 117.974 140.135 124.109 1.00 90.87  ? 548 ARG B CD  1 
ATOM   5729 N NE  . ARG B 1 548 ? 117.718 140.618 125.459 1.00 90.08  ? 548 ARG B NE  1 
ATOM   5730 C CZ  . ARG B 1 548 ? 118.147 141.781 125.926 1.00 84.00  ? 548 ARG B CZ  1 
ATOM   5731 N NH1 . ARG B 1 548 ? 118.836 142.617 125.169 1.00 77.09  ? 548 ARG B NH1 1 
ATOM   5732 N NH2 . ARG B 1 548 ? 117.876 142.114 127.184 1.00 80.85  ? 548 ARG B NH2 1 
ATOM   5733 N N   . GLU B 1 549 ? 115.398 137.509 121.124 1.00 104.65 ? 549 GLU B N   1 
ATOM   5734 C CA  . GLU B 1 549 ? 115.858 136.945 119.859 1.00 102.06 ? 549 GLU B CA  1 
ATOM   5735 C C   . GLU B 1 549 ? 117.368 137.090 119.696 1.00 102.48 ? 549 GLU B C   1 
ATOM   5736 O O   . GLU B 1 549 ? 118.087 136.094 119.563 1.00 99.72  ? 549 GLU B O   1 
ATOM   5737 C CB  . GLU B 1 549 ? 115.131 137.611 118.687 1.00 108.05 ? 549 GLU B CB  1 
ATOM   5738 C CG  . GLU B 1 549 ? 113.690 137.160 118.486 1.00 115.26 ? 549 GLU B CG  1 
ATOM   5739 C CD  . GLU B 1 549 ? 112.714 137.855 119.416 1.00 118.53 ? 549 GLU B CD  1 
ATOM   5740 O OE1 . GLU B 1 549 ? 113.127 138.804 120.113 1.00 117.88 ? 549 GLU B OE1 1 
ATOM   5741 O OE2 . GLU B 1 549 ? 111.532 137.453 119.444 1.00 117.02 ? 549 GLU B OE2 1 
ATOM   5742 N N   . GLU B 1 550 ? 117.867 138.325 119.703 1.00 105.89 ? 550 GLU B N   1 
ATOM   5743 C CA  . GLU B 1 550 ? 119.275 138.595 119.435 1.00 101.39 ? 550 GLU B CA  1 
ATOM   5744 C C   . GLU B 1 550 ? 120.050 138.780 120.731 1.00 94.07  ? 550 GLU B C   1 
ATOM   5745 O O   . GLU B 1 550 ? 119.625 139.512 121.625 1.00 93.86  ? 550 GLU B O   1 
ATOM   5746 C CB  . GLU B 1 550 ? 119.434 139.841 118.561 1.00 100.37 ? 550 GLU B CB  1 
ATOM   5747 C CG  . GLU B 1 550 ? 118.825 139.727 117.173 1.00 101.17 ? 550 GLU B CG  1 
ATOM   5748 C CD  . GLU B 1 550 ? 117.326 139.941 117.171 1.00 105.60 ? 550 GLU B CD  1 
ATOM   5749 O OE1 . GLU B 1 550 ? 116.803 140.495 118.160 1.00 106.63 ? 550 GLU B OE1 1 
ATOM   5750 O OE2 . GLU B 1 550 ? 116.671 139.552 116.181 1.00 103.68 ? 550 GLU B OE2 1 
ATOM   5751 N N   . ILE B 1 551 ? 121.204 138.124 120.818 1.00 91.23  ? 551 ILE B N   1 
ATOM   5752 C CA  . ILE B 1 551 ? 122.062 138.182 121.994 1.00 93.84  ? 551 ILE B CA  1 
ATOM   5753 C C   . ILE B 1 551 ? 123.416 138.730 121.573 1.00 94.66  ? 551 ILE B C   1 
ATOM   5754 O O   . ILE B 1 551 ? 124.006 138.253 120.597 1.00 97.37  ? 551 ILE B O   1 
ATOM   5755 C CB  . ILE B 1 551 ? 122.221 136.798 122.651 1.00 98.93  ? 551 ILE B CB  1 
ATOM   5756 C CG1 . ILE B 1 551 ? 120.914 136.369 123.317 1.00 100.69 ? 551 ILE B CG1 1 
ATOM   5757 C CG2 . ILE B 1 551 ? 123.356 136.811 123.657 1.00 93.70  ? 551 ILE B CG2 1 
ATOM   5758 C CD1 . ILE B 1 551 ? 120.518 137.230 124.490 1.00 88.56  ? 551 ILE B CD1 1 
ATOM   5759 N N   . VAL B 1 552 ? 123.908 139.730 122.304 1.00 91.36  ? 552 VAL B N   1 
ATOM   5760 C CA  . VAL B 1 552 ? 125.220 140.308 122.032 1.00 88.24  ? 552 VAL B CA  1 
ATOM   5761 C C   . VAL B 1 552 ? 126.261 139.915 123.065 1.00 86.96  ? 552 VAL B C   1 
ATOM   5762 O O   . VAL B 1 552 ? 127.456 140.167 122.840 1.00 88.38  ? 552 VAL B O   1 
ATOM   5763 C CB  . VAL B 1 552 ? 125.155 141.846 121.920 1.00 83.35  ? 552 VAL B CB  1 
ATOM   5764 C CG1 . VAL B 1 552 ? 124.023 142.269 121.002 1.00 87.15  ? 552 VAL B CG1 1 
ATOM   5765 C CG2 . VAL B 1 552 ? 125.006 142.466 123.290 1.00 77.02  ? 552 VAL B CG2 1 
ATOM   5766 N N   . TYR B 1 553 ? 125.860 139.322 124.184 1.00 87.40  ? 553 TYR B N   1 
ATOM   5767 C CA  . TYR B 1 553 ? 126.935 138.973 125.100 1.00 87.31  ? 553 TYR B CA  1 
ATOM   5768 C C   . TYR B 1 553 ? 127.307 137.503 124.957 1.00 87.82  ? 553 TYR B C   1 
ATOM   5769 O O   . TYR B 1 553 ? 126.435 136.662 124.718 1.00 88.75  ? 553 TYR B O   1 
ATOM   5770 C CB  . TYR B 1 553 ? 126.534 139.270 126.544 1.00 80.12  ? 553 TYR B CB  1 
ATOM   5771 C CG  . TYR B 1 553 ? 126.446 140.748 126.836 1.00 72.00  ? 553 TYR B CG  1 
ATOM   5772 C CD1 . TYR B 1 553 ? 127.593 141.507 127.016 1.00 71.60  ? 553 TYR B CD1 1 
ATOM   5773 C CD2 . TYR B 1 553 ? 125.220 141.386 126.922 1.00 71.34  ? 553 TYR B CD2 1 
ATOM   5774 C CE1 . TYR B 1 553 ? 127.521 142.857 127.278 1.00 64.09  ? 553 TYR B CE1 1 
ATOM   5775 C CE2 . TYR B 1 553 ? 125.139 142.736 127.184 1.00 70.77  ? 553 TYR B CE2 1 
ATOM   5776 C CZ  . TYR B 1 553 ? 126.291 143.466 127.360 1.00 63.89  ? 553 TYR B CZ  1 
ATOM   5777 O OH  . TYR B 1 553 ? 126.212 144.812 127.622 1.00 53.94  ? 553 TYR B OH  1 
ATOM   5778 N N   . PRO B 1 554 ? 128.598 137.189 125.096 1.00 85.32  ? 554 PRO B N   1 
ATOM   5779 C CA  . PRO B 1 554 ? 129.061 135.834 124.756 1.00 88.35  ? 554 PRO B CA  1 
ATOM   5780 C C   . PRO B 1 554 ? 128.386 134.721 125.536 1.00 89.17  ? 554 PRO B C   1 
ATOM   5781 O O   . PRO B 1 554 ? 128.125 133.654 124.969 1.00 91.48  ? 554 PRO B O   1 
ATOM   5782 C CB  . PRO B 1 554 ? 130.564 135.906 125.056 1.00 92.23  ? 554 PRO B CB  1 
ATOM   5783 C CG  . PRO B 1 554 ? 130.905 137.346 124.883 1.00 86.47  ? 554 PRO B CG  1 
ATOM   5784 C CD  . PRO B 1 554 ? 129.717 138.096 125.398 1.00 84.26  ? 554 PRO B CD  1 
ATOM   5785 N N   . GLN B 1 555 ? 128.090 134.927 126.815 1.00 88.12  ? 555 GLN B N   1 
ATOM   5786 C CA  . GLN B 1 555 ? 127.573 133.864 127.668 1.00 90.76  ? 555 GLN B CA  1 
ATOM   5787 C C   . GLN B 1 555 ? 126.134 134.171 128.051 1.00 88.46  ? 555 GLN B C   1 
ATOM   5788 O O   . GLN B 1 555 ? 125.856 135.212 128.656 1.00 87.58  ? 555 GLN B O   1 
ATOM   5789 C CB  . GLN B 1 555 ? 128.437 133.696 128.916 1.00 91.76  ? 555 GLN B CB  1 
ATOM   5790 C CG  . GLN B 1 555 ? 129.890 133.376 128.613 1.00 94.24  ? 555 GLN B CG  1 
ATOM   5791 C CD  . GLN B 1 555 ? 130.052 132.103 127.807 1.00 97.21  ? 555 GLN B CD  1 
ATOM   5792 O OE1 . GLN B 1 555 ? 129.266 131.164 127.939 1.00 92.68  ? 555 GLN B OE1 1 
ATOM   5793 N NE2 . GLN B 1 555 ? 131.076 132.066 126.963 1.00 100.06 ? 555 GLN B NE2 1 
ATOM   5794 N N   . LYS B 1 556 ? 125.227 133.253 127.711 1.00 86.59  ? 556 LYS B N   1 
ATOM   5795 C CA  . LYS B 1 556 ? 123.822 133.441 128.047 1.00 85.55  ? 556 LYS B CA  1 
ATOM   5796 C C   . LYS B 1 556 ? 123.578 133.315 129.543 1.00 83.03  ? 556 LYS B C   1 
ATOM   5797 O O   . LYS B 1 556 ? 122.673 133.968 130.076 1.00 89.25  ? 556 LYS B O   1 
ATOM   5798 C CB  . LYS B 1 556 ? 122.962 132.433 127.289 1.00 89.60  ? 556 LYS B CB  1 
ATOM   5799 C CG  . LYS B 1 556 ? 123.024 132.563 125.783 1.00 96.13  ? 556 LYS B CG  1 
ATOM   5800 C CD  . LYS B 1 556 ? 122.126 131.531 125.127 1.00 103.66 ? 556 LYS B CD  1 
ATOM   5801 C CE  . LYS B 1 556 ? 122.227 131.588 123.615 1.00 107.73 ? 556 LYS B CE  1 
ATOM   5802 N NZ  . LYS B 1 556 ? 121.362 130.562 122.969 1.00 110.97 ? 556 LYS B NZ  1 
ATOM   5803 N N   . ALA B 1 557 ? 124.375 132.494 130.232 1.00 76.77  ? 557 ALA B N   1 
ATOM   5804 C CA  . ALA B 1 557 ? 124.164 132.272 131.659 1.00 76.07  ? 557 ALA B CA  1 
ATOM   5805 C C   . ALA B 1 557 ? 124.165 133.583 132.431 1.00 80.66  ? 557 ALA B C   1 
ATOM   5806 O O   . ALA B 1 557 ? 123.378 133.756 133.371 1.00 80.67  ? 557 ALA B O   1 
ATOM   5807 C CB  . ALA B 1 557 ? 125.233 131.329 132.205 1.00 76.18  ? 557 ALA B CB  1 
ATOM   5808 N N   . TYR B 1 558 ? 125.023 134.528 132.029 1.00 82.52  ? 558 TYR B N   1 
ATOM   5809 C CA  . TYR B 1 558 ? 125.058 135.837 132.674 1.00 81.10  ? 558 TYR B CA  1 
ATOM   5810 C C   . TYR B 1 558 ? 123.664 136.440 132.750 1.00 79.09  ? 558 TYR B C   1 
ATOM   5811 O O   . TYR B 1 558 ? 123.217 136.862 133.824 1.00 75.87  ? 558 TYR B O   1 
ATOM   5812 C CB  . TYR B 1 558 ? 125.996 136.776 131.914 1.00 80.09  ? 558 TYR B CB  1 
ATOM   5813 C CG  . TYR B 1 558 ? 127.445 136.359 131.929 1.00 86.72  ? 558 TYR B CG  1 
ATOM   5814 C CD1 . TYR B 1 558 ? 127.950 135.575 132.953 1.00 90.91  ? 558 TYR B CD1 1 
ATOM   5815 C CD2 . TYR B 1 558 ? 128.309 136.755 130.918 1.00 88.80  ? 558 TYR B CD2 1 
ATOM   5816 C CE1 . TYR B 1 558 ? 129.271 135.192 132.970 1.00 95.99  ? 558 TYR B CE1 1 
ATOM   5817 C CE2 . TYR B 1 558 ? 129.633 136.378 130.927 1.00 90.91  ? 558 TYR B CE2 1 
ATOM   5818 C CZ  . TYR B 1 558 ? 130.109 135.596 131.956 1.00 98.91  ? 558 TYR B CZ  1 
ATOM   5819 O OH  . TYR B 1 558 ? 131.429 135.214 131.974 1.00 110.71 ? 558 TYR B OH  1 
ATOM   5820 N N   . TYR B 1 559 ? 122.952 136.451 131.619 1.00 78.23  ? 559 TYR B N   1 
ATOM   5821 C CA  . TYR B 1 559 ? 121.575 136.928 131.598 1.00 71.50  ? 559 TYR B CA  1 
ATOM   5822 C C   . TYR B 1 559 ? 120.784 136.328 132.747 1.00 75.48  ? 559 TYR B C   1 
ATOM   5823 O O   . TYR B 1 559 ? 120.259 137.050 133.603 1.00 81.42  ? 559 TYR B O   1 
ATOM   5824 C CB  . TYR B 1 559 ? 120.916 136.581 130.263 1.00 71.11  ? 559 TYR B CB  1 
ATOM   5825 C CG  . TYR B 1 559 ? 121.473 137.325 129.077 1.00 72.40  ? 559 TYR B CG  1 
ATOM   5826 C CD1 . TYR B 1 559 ? 122.644 136.913 128.463 1.00 75.77  ? 559 TYR B CD1 1 
ATOM   5827 C CD2 . TYR B 1 559 ? 120.818 138.432 128.562 1.00 76.47  ? 559 TYR B CD2 1 
ATOM   5828 C CE1 . TYR B 1 559 ? 123.152 137.589 127.377 1.00 79.61  ? 559 TYR B CE1 1 
ATOM   5829 C CE2 . TYR B 1 559 ? 121.319 139.113 127.475 1.00 78.54  ? 559 TYR B CE2 1 
ATOM   5830 C CZ  . TYR B 1 559 ? 122.486 138.688 126.889 1.00 79.23  ? 559 TYR B CZ  1 
ATOM   5831 O OH  . TYR B 1 559 ? 122.990 139.363 125.805 1.00 84.65  ? 559 TYR B OH  1 
ATOM   5832 N N   . TYR B 1 560 ? 120.749 134.995 132.817 1.00 76.66  ? 560 TYR B N   1 
ATOM   5833 C CA  . TYR B 1 560 ? 119.963 134.340 133.855 1.00 79.08  ? 560 TYR B CA  1 
ATOM   5834 C C   . TYR B 1 560 ? 120.438 134.759 135.235 1.00 79.37  ? 560 TYR B C   1 
ATOM   5835 O O   . TYR B 1 560 ? 119.620 135.041 136.120 1.00 75.27  ? 560 TYR B O   1 
ATOM   5836 C CB  . TYR B 1 560 ? 120.032 132.822 133.692 1.00 83.44  ? 560 TYR B CB  1 
ATOM   5837 C CG  . TYR B 1 560 ? 119.483 132.326 132.374 1.00 85.05  ? 560 TYR B CG  1 
ATOM   5838 C CD1 . TYR B 1 560 ? 118.129 132.065 132.218 1.00 86.33  ? 560 TYR B CD1 1 
ATOM   5839 C CD2 . TYR B 1 560 ? 120.318 132.119 131.286 1.00 84.92  ? 560 TYR B CD2 1 
ATOM   5840 C CE1 . TYR B 1 560 ? 117.624 131.613 131.017 1.00 88.01  ? 560 TYR B CE1 1 
ATOM   5841 C CE2 . TYR B 1 560 ? 119.822 131.668 130.081 1.00 85.60  ? 560 TYR B CE2 1 
ATOM   5842 C CZ  . TYR B 1 560 ? 118.475 131.417 129.954 1.00 90.61  ? 560 TYR B CZ  1 
ATOM   5843 O OH  . TYR B 1 560 ? 117.975 130.966 128.757 1.00 99.40  ? 560 TYR B OH  1 
ATOM   5844 N N   . CYS B 1 561 ? 121.755 134.851 135.422 1.00 80.44  ? 561 CYS B N   1 
ATOM   5845 C CA  . CYS B 1 561 ? 122.303 135.300 136.692 1.00 79.49  ? 561 CYS B CA  1 
ATOM   5846 C C   . CYS B 1 561 ? 121.696 136.650 137.041 1.00 79.26  ? 561 CYS B C   1 
ATOM   5847 O O   . CYS B 1 561 ? 121.111 136.815 138.119 1.00 82.22  ? 561 CYS B O   1 
ATOM   5848 C CB  . CYS B 1 561 ? 123.829 135.390 136.623 1.00 77.80  ? 561 CYS B CB  1 
ATOM   5849 S SG  . CYS B 1 561 ? 124.657 133.824 136.260 1.00 77.49  ? 561 CYS B SG  1 
ATOM   5850 N N   . ALA B 1 562 ? 121.757 137.590 136.096 1.00 72.80  ? 562 ALA B N   1 
ATOM   5851 C CA  . ALA B 1 562 ? 121.198 138.913 136.323 1.00 70.45  ? 562 ALA B CA  1 
ATOM   5852 C C   . ALA B 1 562 ? 119.730 138.814 136.703 1.00 72.45  ? 562 ALA B C   1 
ATOM   5853 O O   . ALA B 1 562 ? 119.270 139.484 137.634 1.00 75.23  ? 562 ALA B O   1 
ATOM   5854 C CB  . ALA B 1 562 ? 121.381 139.778 135.077 1.00 70.94  ? 562 ALA B CB  1 
ATOM   5855 N N   . ILE B 1 563 ? 118.995 137.939 136.014 1.00 73.09  ? 563 ILE B N   1 
ATOM   5856 C CA  . ILE B 1 563 ? 117.563 137.789 136.241 1.00 68.54  ? 563 ILE B CA  1 
ATOM   5857 C C   . ILE B 1 563 ? 117.339 137.439 137.701 1.00 70.97  ? 563 ILE B C   1 
ATOM   5858 O O   . ILE B 1 563 ? 116.446 137.990 138.352 1.00 74.35  ? 563 ILE B O   1 
ATOM   5859 C CB  . ILE B 1 563 ? 116.945 136.723 135.324 1.00 64.76  ? 563 ILE B CB  1 
ATOM   5860 C CG1 . ILE B 1 563 ? 117.044 137.155 133.866 1.00 71.48  ? 563 ILE B CG1 1 
ATOM   5861 C CG2 . ILE B 1 563 ? 115.501 136.481 135.703 1.00 58.01  ? 563 ILE B CG2 1 
ATOM   5862 C CD1 . ILE B 1 563 ? 116.332 136.232 132.918 1.00 76.43  ? 563 ILE B CD1 1 
ATOM   5863 N N   . ILE B 1 564 ? 118.155 136.533 138.233 1.00 73.43  ? 564 ILE B N   1 
ATOM   5864 C CA  . ILE B 1 564 ? 118.051 136.231 139.653 1.00 75.57  ? 564 ILE B CA  1 
ATOM   5865 C C   . ILE B 1 564 ? 118.497 137.428 140.475 1.00 74.82  ? 564 ILE B C   1 
ATOM   5866 O O   . ILE B 1 564 ? 117.784 137.880 141.380 1.00 73.70  ? 564 ILE B O   1 
ATOM   5867 C CB  . ILE B 1 564 ? 118.864 134.972 140.002 1.00 79.14  ? 564 ILE B CB  1 
ATOM   5868 C CG1 . ILE B 1 564 ? 118.356 133.770 139.206 1.00 80.42  ? 564 ILE B CG1 1 
ATOM   5869 C CG2 . ILE B 1 564 ? 118.787 134.687 141.492 1.00 79.51  ? 564 ILE B CG2 1 
ATOM   5870 C CD1 . ILE B 1 564 ? 116.907 133.431 139.474 1.00 78.45  ? 564 ILE B CD1 1 
ATOM   5871 N N   . GLU B 1 565 ? 119.654 137.991 140.130 1.00 73.67  ? 565 GLU B N   1 
ATOM   5872 C CA  . GLU B 1 565 ? 120.290 139.013 140.948 1.00 76.96  ? 565 GLU B CA  1 
ATOM   5873 C C   . GLU B 1 565 ? 119.374 140.215 141.115 1.00 78.69  ? 565 GLU B C   1 
ATOM   5874 O O   . GLU B 1 565 ? 119.058 140.610 142.243 1.00 82.13  ? 565 GLU B O   1 
ATOM   5875 C CB  . GLU B 1 565 ? 121.624 139.424 140.326 1.00 78.71  ? 565 GLU B CB  1 
ATOM   5876 C CG  . GLU B 1 565 ? 122.403 140.429 141.137 1.00 88.99  ? 565 GLU B CG  1 
ATOM   5877 C CD  . GLU B 1 565 ? 122.219 141.842 140.642 1.00 98.34  ? 565 GLU B CD  1 
ATOM   5878 O OE1 . GLU B 1 565 ? 121.316 142.076 139.813 1.00 97.43  ? 565 GLU B OE1 1 
ATOM   5879 O OE2 . GLU B 1 565 ? 122.988 142.718 141.078 1.00 100.69 ? 565 GLU B OE2 1 
ATOM   5880 N N   . ASP B 1 566 ? 118.898 140.764 139.996 1.00 75.35  ? 566 ASP B N   1 
ATOM   5881 C CA  . ASP B 1 566 ? 117.954 141.870 140.057 1.00 68.28  ? 566 ASP B CA  1 
ATOM   5882 C C   . ASP B 1 566 ? 116.789 141.511 140.964 1.00 70.11  ? 566 ASP B C   1 
ATOM   5883 O O   . ASP B 1 566 ? 116.438 142.271 141.871 1.00 70.96  ? 566 ASP B O   1 
ATOM   5884 C CB  . ASP B 1 566 ? 117.463 142.217 138.650 1.00 66.25  ? 566 ASP B CB  1 
ATOM   5885 C CG  . ASP B 1 566 ? 116.770 143.567 138.583 1.00 71.97  ? 566 ASP B CG  1 
ATOM   5886 O OD1 . ASP B 1 566 ? 116.174 143.997 139.590 1.00 74.32  ? 566 ASP B OD1 1 
ATOM   5887 O OD2 . ASP B 1 566 ? 116.819 144.205 137.512 1.00 71.09  ? 566 ASP B OD2 1 
ATOM   5888 N N   . VAL B 1 567 ? 116.224 140.317 140.777 1.00 70.68  ? 567 VAL B N   1 
ATOM   5889 C CA  . VAL B 1 567 ? 115.054 139.927 141.558 1.00 73.59  ? 567 VAL B CA  1 
ATOM   5890 C C   . VAL B 1 567 ? 115.369 139.948 143.045 1.00 75.07  ? 567 VAL B C   1 
ATOM   5891 O O   . VAL B 1 567 ? 114.541 140.381 143.856 1.00 71.39  ? 567 VAL B O   1 
ATOM   5892 C CB  . VAL B 1 567 ? 114.538 138.547 141.096 1.00 75.39  ? 567 VAL B CB  1 
ATOM   5893 C CG1 . VAL B 1 567 ? 113.640 137.929 142.148 1.00 74.27  ? 567 VAL B CG1 1 
ATOM   5894 C CG2 . VAL B 1 567 ? 113.778 138.684 139.794 1.00 70.52  ? 567 VAL B CG2 1 
ATOM   5895 N N   . ILE B 1 568 ? 116.569 139.520 143.432 1.00 73.59  ? 568 ILE B N   1 
ATOM   5896 C CA  . ILE B 1 568 ? 116.932 139.482 144.844 1.00 72.16  ? 568 ILE B CA  1 
ATOM   5897 C C   . ILE B 1 568 ? 117.579 140.770 145.319 1.00 70.48  ? 568 ILE B C   1 
ATOM   5898 O O   . ILE B 1 568 ? 117.911 140.870 146.512 1.00 70.59  ? 568 ILE B O   1 
ATOM   5899 C CB  . ILE B 1 568 ? 117.839 138.277 145.169 1.00 73.85  ? 568 ILE B CB  1 
ATOM   5900 C CG1 . ILE B 1 568 ? 119.129 138.327 144.353 1.00 72.45  ? 568 ILE B CG1 1 
ATOM   5901 C CG2 . ILE B 1 568 ? 117.097 136.975 144.918 1.00 77.22  ? 568 ILE B CG2 1 
ATOM   5902 C CD1 . ILE B 1 568 ? 120.030 137.137 144.564 1.00 75.09  ? 568 ILE B CD1 1 
ATOM   5903 N N   . LEU B 1 569 ? 117.756 141.761 144.445 1.00 68.33  ? 569 LEU B N   1 
ATOM   5904 C CA  . LEU B 1 569 ? 118.291 143.054 144.848 1.00 65.50  ? 569 LEU B CA  1 
ATOM   5905 C C   . LEU B 1 569 ? 117.383 144.203 144.442 1.00 68.62  ? 569 LEU B C   1 
ATOM   5906 O O   . LEU B 1 569 ? 117.641 145.348 144.827 1.00 70.63  ? 569 LEU B O   1 
ATOM   5907 C CB  . LEU B 1 569 ? 119.692 143.262 144.269 1.00 63.68  ? 569 LEU B CB  1 
ATOM   5908 C CG  . LEU B 1 569 ? 120.794 142.408 144.893 1.00 59.69  ? 569 LEU B CG  1 
ATOM   5909 C CD1 . LEU B 1 569 ? 122.104 142.604 144.164 1.00 55.49  ? 569 LEU B CD1 1 
ATOM   5910 C CD2 . LEU B 1 569 ? 120.949 142.754 146.357 1.00 57.59  ? 569 LEU B CD2 1 
ATOM   5911 N N   . ARG B 1 570 ? 116.339 143.935 143.660 1.00 69.74  ? 570 ARG B N   1 
ATOM   5912 C CA  . ARG B 1 570 ? 115.321 144.945 143.417 1.00 70.24  ? 570 ARG B CA  1 
ATOM   5913 C C   . ARG B 1 570 ? 114.407 145.107 144.620 1.00 74.45  ? 570 ARG B C   1 
ATOM   5914 O O   . ARG B 1 570 ? 113.988 146.225 144.932 1.00 79.11  ? 570 ARG B O   1 
ATOM   5915 C CB  . ARG B 1 570 ? 114.498 144.593 142.177 1.00 64.29  ? 570 ARG B CB  1 
ATOM   5916 C CG  . ARG B 1 570 ? 113.481 145.644 141.814 1.00 72.00  ? 570 ARG B CG  1 
ATOM   5917 C CD  . ARG B 1 570 ? 114.111 147.021 141.727 1.00 73.59  ? 570 ARG B CD  1 
ATOM   5918 N NE  . ARG B 1 570 ? 114.565 147.345 140.382 1.00 69.85  ? 570 ARG B NE  1 
ATOM   5919 C CZ  . ARG B 1 570 ? 114.972 148.550 140.011 1.00 70.79  ? 570 ARG B CZ  1 
ATOM   5920 N NH1 . ARG B 1 570 ? 114.973 149.566 140.855 1.00 75.12  ? 570 ARG B NH1 1 
ATOM   5921 N NH2 . ARG B 1 570 ? 115.392 148.739 138.765 1.00 70.72  ? 570 ARG B NH2 1 
ATOM   5922 N N   . PHE B 1 571 ? 114.085 144.007 145.303 1.00 72.13  ? 571 PHE B N   1 
ATOM   5923 C CA  . PHE B 1 571 ? 113.414 144.119 146.592 1.00 72.63  ? 571 PHE B CA  1 
ATOM   5924 C C   . PHE B 1 571 ? 114.313 144.800 147.614 1.00 74.47  ? 571 PHE B C   1 
ATOM   5925 O O   . PHE B 1 571 ? 113.869 145.697 148.340 1.00 77.15  ? 571 PHE B O   1 
ATOM   5926 C CB  . PHE B 1 571 ? 112.991 142.738 147.089 1.00 74.30  ? 571 PHE B CB  1 
ATOM   5927 C CG  . PHE B 1 571 ? 111.823 142.162 146.351 1.00 71.61  ? 571 PHE B CG  1 
ATOM   5928 C CD1 . PHE B 1 571 ? 112.003 141.493 145.156 1.00 67.18  ? 571 PHE B CD1 1 
ATOM   5929 C CD2 . PHE B 1 571 ? 110.543 142.286 146.856 1.00 71.44  ? 571 PHE B CD2 1 
ATOM   5930 C CE1 . PHE B 1 571 ? 110.931 140.965 144.475 1.00 68.95  ? 571 PHE B CE1 1 
ATOM   5931 C CE2 . PHE B 1 571 ? 109.467 141.759 146.180 1.00 71.29  ? 571 PHE B CE2 1 
ATOM   5932 C CZ  . PHE B 1 571 ? 109.661 141.097 144.987 1.00 73.24  ? 571 PHE B CZ  1 
ATOM   5933 N N   . ALA B 1 572 ? 115.589 144.414 147.656 1.00 75.28  ? 572 ALA B N   1 
ATOM   5934 C CA  . ALA B 1 572 ? 116.505 144.979 148.638 1.00 79.45  ? 572 ALA B CA  1 
ATOM   5935 C C   . ALA B 1 572 ? 116.633 146.487 148.471 1.00 80.72  ? 572 ALA B C   1 
ATOM   5936 O O   . ALA B 1 572 ? 116.700 147.223 149.463 1.00 84.19  ? 572 ALA B O   1 
ATOM   5937 C CB  . ALA B 1 572 ? 117.872 144.309 148.526 1.00 78.69  ? 572 ALA B CB  1 
ATOM   5938 N N   . TRP B 1 573 ? 116.655 146.969 147.226 1.00 78.73  ? 573 TRP B N   1 
ATOM   5939 C CA  . TRP B 1 573 ? 116.709 148.410 147.006 1.00 77.32  ? 573 TRP B CA  1 
ATOM   5940 C C   . TRP B 1 573 ? 115.502 149.097 147.619 1.00 77.96  ? 573 TRP B C   1 
ATOM   5941 O O   . TRP B 1 573 ? 115.622 150.185 148.191 1.00 81.38  ? 573 TRP B O   1 
ATOM   5942 C CB  . TRP B 1 573 ? 116.788 148.734 145.517 1.00 78.27  ? 573 TRP B CB  1 
ATOM   5943 C CG  . TRP B 1 573 ? 116.353 150.142 145.223 1.00 81.37  ? 573 TRP B CG  1 
ATOM   5944 C CD1 . TRP B 1 573 ? 117.009 151.289 145.561 1.00 80.57  ? 573 TRP B CD1 1 
ATOM   5945 C CD2 . TRP B 1 573 ? 115.160 150.549 144.544 1.00 80.34  ? 573 TRP B CD2 1 
ATOM   5946 N NE1 . TRP B 1 573 ? 116.301 152.383 145.133 1.00 74.28  ? 573 TRP B NE1 1 
ATOM   5947 C CE2 . TRP B 1 573 ? 115.162 151.956 144.505 1.00 76.55  ? 573 TRP B CE2 1 
ATOM   5948 C CE3 . TRP B 1 573 ? 114.092 149.861 143.963 1.00 79.59  ? 573 TRP B CE3 1 
ATOM   5949 C CZ2 . TRP B 1 573 ? 114.140 152.686 143.911 1.00 76.38  ? 573 TRP B CZ2 1 
ATOM   5950 C CZ3 . TRP B 1 573 ? 113.076 150.588 143.376 1.00 81.87  ? 573 TRP B CZ3 1 
ATOM   5951 C CH2 . TRP B 1 573 ? 113.109 151.986 143.352 1.00 81.76  ? 573 TRP B CH2 1 
ATOM   5952 N N   . THR B 1 574 ? 114.329 148.480 147.513 1.00 79.95  ? 574 THR B N   1 
ATOM   5953 C CA  . THR B 1 574 ? 113.159 149.063 148.146 1.00 85.05  ? 574 THR B CA  1 
ATOM   5954 C C   . THR B 1 574 ? 113.213 148.969 149.662 1.00 90.10  ? 574 THR B C   1 
ATOM   5955 O O   . THR B 1 574 ? 112.545 149.755 150.337 1.00 93.29  ? 574 THR B O   1 
ATOM   5956 C CB  . THR B 1 574 ? 111.888 148.392 147.628 1.00 84.40  ? 574 THR B CB  1 
ATOM   5957 O OG1 . THR B 1 574 ? 112.052 146.969 147.655 1.00 83.32  ? 574 THR B OG1 1 
ATOM   5958 C CG2 . THR B 1 574 ? 111.602 148.831 146.207 1.00 78.74  ? 574 THR B CG2 1 
ATOM   5959 N N   . ILE B 1 575 ? 114.013 148.060 150.213 1.00 88.11  ? 575 ILE B N   1 
ATOM   5960 C CA  . ILE B 1 575 ? 114.117 147.951 151.663 1.00 88.25  ? 575 ILE B CA  1 
ATOM   5961 C C   . ILE B 1 575 ? 114.927 149.111 152.226 1.00 89.37  ? 575 ILE B C   1 
ATOM   5962 O O   . ILE B 1 575 ? 114.434 149.897 153.044 1.00 94.34  ? 575 ILE B O   1 
ATOM   5963 C CB  . ILE B 1 575 ? 114.723 146.594 152.059 1.00 89.28  ? 575 ILE B CB  1 
ATOM   5964 C CG1 . ILE B 1 575 ? 113.857 145.452 151.528 1.00 87.07  ? 575 ILE B CG1 1 
ATOM   5965 C CG2 . ILE B 1 575 ? 114.854 146.494 153.565 1.00 95.89  ? 575 ILE B CG2 1 
ATOM   5966 C CD1 . ILE B 1 575 ? 114.332 144.078 151.941 1.00 85.55  ? 575 ILE B CD1 1 
ATOM   5967 N N   . GLN B 1 576 ? 116.174 149.252 151.768 1.00 87.47  ? 576 GLN B N   1 
ATOM   5968 C CA  . GLN B 1 576 ? 117.037 150.313 152.276 1.00 88.39  ? 576 GLN B CA  1 
ATOM   5969 C C   . GLN B 1 576 ? 116.428 151.686 152.040 1.00 92.14  ? 576 GLN B C   1 
ATOM   5970 O O   . GLN B 1 576 ? 116.490 152.559 152.914 1.00 96.78  ? 576 GLN B O   1 
ATOM   5971 C CB  . GLN B 1 576 ? 118.414 150.229 151.623 1.00 86.16  ? 576 GLN B CB  1 
ATOM   5972 C CG  . GLN B 1 576 ? 119.288 151.433 151.915 1.00 86.42  ? 576 GLN B CG  1 
ATOM   5973 C CD  . GLN B 1 576 ? 120.606 151.393 151.180 1.00 84.76  ? 576 GLN B CD  1 
ATOM   5974 O OE1 . GLN B 1 576 ? 120.801 150.585 150.273 1.00 78.46  ? 576 GLN B OE1 1 
ATOM   5975 N NE2 . GLN B 1 576 ? 121.526 152.267 151.570 1.00 89.72  ? 576 GLN B NE2 1 
ATOM   5976 N N   . ILE B 1 577 ? 115.816 151.891 150.870 1.00 93.99  ? 577 ILE B N   1 
ATOM   5977 C CA  . ILE B 1 577 ? 115.250 153.195 150.540 1.00 94.43  ? 577 ILE B CA  1 
ATOM   5978 C C   . ILE B 1 577 ? 114.149 153.577 151.517 1.00 98.32  ? 577 ILE B C   1 
ATOM   5979 O O   . ILE B 1 577 ? 113.777 154.752 151.614 1.00 101.92 ? 577 ILE B O   1 
ATOM   5980 C CB  . ILE B 1 577 ? 114.743 153.206 149.086 1.00 87.05  ? 577 ILE B CB  1 
ATOM   5981 C CG1 . ILE B 1 577 ? 114.819 154.620 148.524 1.00 85.87  ? 577 ILE B CG1 1 
ATOM   5982 C CG2 . ILE B 1 577 ? 113.318 152.705 149.014 1.00 89.31  ? 577 ILE B CG2 1 
ATOM   5983 C CD1 . ILE B 1 577 ? 116.194 155.231 148.639 1.00 89.79  ? 577 ILE B CD1 1 
ATOM   5984 N N   . SER B 1 578 ? 113.602 152.605 152.246 1.00 98.90  ? 578 SER B N   1 
ATOM   5985 C CA  . SER B 1 578 ? 112.643 152.916 153.296 1.00 98.01  ? 578 SER B CA  1 
ATOM   5986 C C   . SER B 1 578 ? 113.295 153.000 154.667 1.00 100.05 ? 578 SER B C   1 
ATOM   5987 O O   . SER B 1 578 ? 112.825 153.758 155.523 1.00 103.92 ? 578 SER B O   1 
ATOM   5988 C CB  . SER B 1 578 ? 111.522 151.872 153.319 1.00 95.54  ? 578 SER B CB  1 
ATOM   5989 O OG  . SER B 1 578 ? 112.043 150.565 153.475 1.00 100.41 ? 578 SER B OG  1 
ATOM   5990 N N   . ILE B 1 579 ? 114.372 152.247 154.891 1.00 97.68  ? 579 ILE B N   1 
ATOM   5991 C CA  . ILE B 1 579 ? 115.020 152.245 156.198 1.00 100.57 ? 579 ILE B CA  1 
ATOM   5992 C C   . ILE B 1 579 ? 115.707 153.580 156.457 1.00 105.08 ? 579 ILE B C   1 
ATOM   5993 O O   . ILE B 1 579 ? 115.626 154.133 157.558 1.00 110.18 ? 579 ILE B O   1 
ATOM   5994 C CB  . ILE B 1 579 ? 116.009 151.072 156.305 1.00 99.95  ? 579 ILE B CB  1 
ATOM   5995 C CG1 . ILE B 1 579 ? 115.280 149.741 156.128 1.00 95.65  ? 579 ILE B CG1 1 
ATOM   5996 C CG2 . ILE B 1 579 ? 116.724 151.102 157.642 1.00 106.10 ? 579 ILE B CG2 1 
ATOM   5997 C CD1 . ILE B 1 579 ? 116.187 148.543 156.217 1.00 93.30  ? 579 ILE B CD1 1 
ATOM   5998 N N   . THR B 1 580 ? 116.401 154.115 155.452 1.00 106.85 ? 580 THR B N   1 
ATOM   5999 C CA  . THR B 1 580 ? 117.121 155.369 155.649 1.00 107.02 ? 580 THR B CA  1 
ATOM   6000 C C   . THR B 1 580 ? 116.162 156.544 155.779 1.00 106.51 ? 580 THR B C   1 
ATOM   6001 O O   . THR B 1 580 ? 116.454 157.517 156.482 1.00 106.16 ? 580 THR B O   1 
ATOM   6002 C CB  . THR B 1 580 ? 118.096 155.610 154.495 1.00 109.53 ? 580 THR B CB  1 
ATOM   6003 O OG1 . THR B 1 580 ? 117.362 155.832 153.285 1.00 108.01 ? 580 THR B OG1 1 
ATOM   6004 C CG2 . THR B 1 580 ? 119.008 154.414 154.312 1.00 102.38 ? 580 THR B CG2 1 
ATOM   6005 N N   . SER B 1 581 ? 115.010 156.468 155.109 1.00 106.15 ? 581 SER B N   1 
ATOM   6006 C CA  . SER B 1 581 ? 114.103 157.608 155.040 1.00 108.21 ? 581 SER B CA  1 
ATOM   6007 C C   . SER B 1 581 ? 113.549 158.000 156.404 1.00 115.50 ? 581 SER B C   1 
ATOM   6008 O O   . SER B 1 581 ? 113.168 159.159 156.606 1.00 117.48 ? 581 SER B O   1 
ATOM   6009 C CB  . SER B 1 581 ? 112.954 157.301 154.078 1.00 102.17 ? 581 SER B CB  1 
ATOM   6010 O OG  . SER B 1 581 ? 113.430 157.115 152.758 1.00 101.13 ? 581 SER B OG  1 
ATOM   6011 N N   . THR B 1 582 ? 113.487 157.063 157.346 1.00 116.62 ? 582 THR B N   1 
ATOM   6012 C CA  . THR B 1 582 ? 112.915 157.350 158.656 1.00 118.26 ? 582 THR B CA  1 
ATOM   6013 C C   . THR B 1 582 ? 113.457 156.343 159.662 1.00 120.28 ? 582 THR B C   1 
ATOM   6014 O O   . THR B 1 582 ? 114.416 155.618 159.391 1.00 121.38 ? 582 THR B O   1 
ATOM   6015 C CB  . THR B 1 582 ? 111.386 157.323 158.610 1.00 119.69 ? 582 THR B CB  1 
ATOM   6016 O OG1 . THR B 1 582 ? 110.865 157.756 159.871 1.00 124.12 ? 582 THR B OG1 1 
ATOM   6017 C CG2 . THR B 1 582 ? 110.886 155.916 158.306 1.00 116.36 ? 582 THR B CG2 1 
ATOM   6018 N N   . THR B 1 583 ? 112.838 156.315 160.844 1.00 124.73 ? 583 THR B N   1 
ATOM   6019 C CA  . THR B 1 583 ? 113.291 155.420 161.903 1.00 128.15 ? 583 THR B CA  1 
ATOM   6020 C C   . THR B 1 583 ? 113.145 153.959 161.493 1.00 128.40 ? 583 THR B C   1 
ATOM   6021 O O   . THR B 1 583 ? 114.138 153.235 161.360 1.00 128.53 ? 583 THR B O   1 
ATOM   6022 C CB  . THR B 1 583 ? 112.514 155.699 163.192 1.00 129.22 ? 583 THR B CB  1 
ATOM   6023 O OG1 . THR B 1 583 ? 112.722 157.058 163.594 1.00 126.76 ? 583 THR B OG1 1 
ATOM   6024 C CG2 . THR B 1 583 ? 112.981 154.773 164.304 1.00 127.57 ? 583 THR B CG2 1 
ATOM   6025 N N   . LEU B 1 584 ? 111.906 153.516 161.271 1.00 128.05 ? 584 LEU B N   1 
ATOM   6026 C CA  . LEU B 1 584 ? 111.579 152.109 160.999 1.00 128.39 ? 584 LEU B CA  1 
ATOM   6027 C C   . LEU B 1 584 ? 112.199 151.269 162.116 1.00 130.96 ? 584 LEU B C   1 
ATOM   6028 O O   . LEU B 1 584 ? 111.969 151.569 163.296 1.00 129.64 ? 584 LEU B O   1 
ATOM   6029 C CB  . LEU B 1 584 ? 112.010 151.739 159.589 1.00 123.80 ? 584 LEU B CB  1 
ATOM   6030 C CG  . LEU B 1 584 ? 111.044 152.100 158.464 1.00 122.42 ? 584 LEU B CG  1 
ATOM   6031 C CD1 . LEU B 1 584 ? 111.441 151.381 157.190 1.00 114.87 ? 584 LEU B CD1 1 
ATOM   6032 C CD2 . LEU B 1 584 ? 109.621 151.750 158.856 1.00 123.41 ? 584 LEU B CD2 1 
ATOM   6033 N N   . LEU B 1 585 ? 112.974 150.241 161.806 1.00 130.10 ? 585 LEU B N   1 
ATOM   6034 C CA  . LEU B 1 585 ? 113.638 149.468 162.845 1.00 128.67 ? 585 LEU B CA  1 
ATOM   6035 C C   . LEU B 1 585 ? 114.757 150.298 163.459 1.00 127.86 ? 585 LEU B C   1 
ATOM   6036 O O   . LEU B 1 585 ? 115.661 150.735 162.734 1.00 125.44 ? 585 LEU B O   1 
ATOM   6037 C CB  . LEU B 1 585 ? 114.181 148.164 162.272 1.00 128.68 ? 585 LEU B CB  1 
ATOM   6038 C CG  . LEU B 1 585 ? 114.931 148.234 160.943 1.00 125.00 ? 585 LEU B CG  1 
ATOM   6039 C CD1 . LEU B 1 585 ? 116.350 147.736 161.116 1.00 124.69 ? 585 LEU B CD1 1 
ATOM   6040 C CD2 . LEU B 1 585 ? 114.207 147.426 159.886 1.00 120.66 ? 585 LEU B CD2 1 
ATOM   6041 N N   . PRO B 1 586 ? 114.738 150.551 164.766 1.00 131.55 ? 586 PRO B N   1 
ATOM   6042 C CA  . PRO B 1 586 ? 115.769 151.408 165.364 1.00 134.44 ? 586 PRO B CA  1 
ATOM   6043 C C   . PRO B 1 586 ? 117.072 150.668 165.618 1.00 133.73 ? 586 PRO B C   1 
ATOM   6044 O O   . PRO B 1 586 ? 118.154 151.260 165.546 1.00 128.45 ? 586 PRO B O   1 
ATOM   6045 C CB  . PRO B 1 586 ? 115.118 151.867 166.673 1.00 135.44 ? 586 PRO B CB  1 
ATOM   6046 C CG  . PRO B 1 586 ? 114.209 150.740 167.039 1.00 133.67 ? 586 PRO B CG  1 
ATOM   6047 C CD  . PRO B 1 586 ? 113.708 150.152 165.742 1.00 132.78 ? 586 PRO B CD  1 
ATOM   6048 N N   . HIS B 1 587 ? 116.980 149.374 165.913 1.00 134.58 ? 587 HIS B N   1 
ATOM   6049 C CA  . HIS B 1 587 ? 118.168 148.589 166.213 1.00 132.98 ? 587 HIS B CA  1 
ATOM   6050 C C   . HIS B 1 587 ? 118.968 148.347 164.942 1.00 130.24 ? 587 HIS B C   1 
ATOM   6051 O O   . HIS B 1 587 ? 118.409 147.965 163.909 1.00 131.46 ? 587 HIS B O   1 
ATOM   6052 C CB  . HIS B 1 587 ? 117.777 147.263 166.860 1.00 136.43 ? 587 HIS B CB  1 
ATOM   6053 C CG  . HIS B 1 587 ? 117.033 147.420 168.149 1.00 140.83 ? 587 HIS B CG  1 
ATOM   6054 N ND1 . HIS B 1 587 ? 117.670 147.564 169.363 1.00 141.60 ? 587 HIS B ND1 1 
ATOM   6055 C CD2 . HIS B 1 587 ? 115.706 147.463 168.413 1.00 139.99 ? 587 HIS B CD2 1 
ATOM   6056 C CE1 . HIS B 1 587 ? 116.767 147.685 170.320 1.00 139.89 ? 587 HIS B CE1 1 
ATOM   6057 N NE2 . HIS B 1 587 ? 115.567 147.627 169.770 1.00 139.49 ? 587 HIS B NE2 1 
ATOM   6058 N N   . SER B 1 588 ? 120.282 148.563 165.026 1.00 130.02 ? 588 SER B N   1 
ATOM   6059 C CA  . SER B 1 588 ? 121.172 148.483 163.872 1.00 128.63 ? 588 SER B CA  1 
ATOM   6060 C C   . SER B 1 588 ? 120.671 149.390 162.755 1.00 123.97 ? 588 SER B C   1 
ATOM   6061 O O   . SER B 1 588 ? 120.919 150.600 162.772 1.00 122.39 ? 588 SER B O   1 
ATOM   6062 C CB  . SER B 1 588 ? 121.302 147.039 163.379 1.00 128.82 ? 588 SER B CB  1 
ATOM   6063 O OG  . SER B 1 588 ? 120.082 146.568 162.832 1.00 130.86 ? 588 SER B OG  1 
ATOM   6064 N N   . GLY B 1 589 ? 119.969 148.817 161.780 1.00 120.69 ? 589 GLY B N   1 
ATOM   6065 C CA  . GLY B 1 589 ? 119.370 149.604 160.719 1.00 115.91 ? 589 GLY B CA  1 
ATOM   6066 C C   . GLY B 1 589 ? 120.377 150.162 159.737 1.00 110.90 ? 589 GLY B C   1 
ATOM   6067 O O   . GLY B 1 589 ? 120.306 149.882 158.537 1.00 106.75 ? 589 GLY B O   1 
ATOM   6068 N N   . ASP B 1 590 ? 121.322 150.959 160.240 1.00 107.93 ? 590 ASP B N   1 
ATOM   6069 C CA  . ASP B 1 590 ? 122.371 151.496 159.385 1.00 101.53 ? 590 ASP B CA  1 
ATOM   6070 C C   . ASP B 1 590 ? 123.250 150.403 158.803 1.00 101.09 ? 590 ASP B C   1 
ATOM   6071 O O   . ASP B 1 590 ? 123.868 150.617 157.757 1.00 97.09  ? 590 ASP B O   1 
ATOM   6072 C CB  . ASP B 1 590 ? 123.232 152.489 160.162 1.00 101.26 ? 590 ASP B CB  1 
ATOM   6073 C CG  . ASP B 1 590 ? 122.475 153.735 160.544 1.00 104.79 ? 590 ASP B CG  1 
ATOM   6074 O OD1 . ASP B 1 590 ? 121.646 153.665 161.474 1.00 110.87 ? 590 ASP B OD1 1 
ATOM   6075 O OD2 . ASP B 1 590 ? 122.709 154.788 159.915 1.00 103.69 ? 590 ASP B OD2 1 
ATOM   6076 N N   . ILE B 1 591 ? 123.332 149.244 159.458 1.00 101.56 ? 591 ILE B N   1 
ATOM   6077 C CA  . ILE B 1 591 ? 124.087 148.131 158.892 1.00 97.42  ? 591 ILE B CA  1 
ATOM   6078 C C   . ILE B 1 591 ? 123.457 147.684 157.582 1.00 95.99  ? 591 ILE B C   1 
ATOM   6079 O O   . ILE B 1 591 ? 124.147 147.480 156.577 1.00 92.49  ? 591 ILE B O   1 
ATOM   6080 C CB  . ILE B 1 591 ? 124.173 146.970 159.896 1.00 96.67  ? 591 ILE B CB  1 
ATOM   6081 C CG1 . ILE B 1 591 ? 124.855 147.431 161.182 1.00 95.77  ? 591 ILE B CG1 1 
ATOM   6082 C CG2 . ILE B 1 591 ? 124.925 145.803 159.289 1.00 93.50  ? 591 ILE B CG2 1 
ATOM   6083 C CD1 . ILE B 1 591 ? 125.075 146.326 162.186 1.00 97.19  ? 591 ILE B CD1 1 
ATOM   6084 N N   . ILE B 1 592 ? 122.130 147.537 157.573 1.00 99.74  ? 592 ILE B N   1 
ATOM   6085 C CA  . ILE B 1 592 ? 121.440 147.096 156.365 1.00 99.90  ? 592 ILE B CA  1 
ATOM   6086 C C   . ILE B 1 592 ? 121.614 148.116 155.251 1.00 95.66  ? 592 ILE B C   1 
ATOM   6087 O O   . ILE B 1 592 ? 121.856 147.755 154.095 1.00 90.75  ? 592 ILE B O   1 
ATOM   6088 C CB  . ILE B 1 592 ? 119.955 146.824 156.662 1.00 98.82  ? 592 ILE B CB  1 
ATOM   6089 C CG1 . ILE B 1 592 ? 119.820 145.744 157.735 1.00 100.83 ? 592 ILE B CG1 1 
ATOM   6090 C CG2 . ILE B 1 592 ? 119.229 146.399 155.398 1.00 91.13  ? 592 ILE B CG2 1 
ATOM   6091 C CD1 . ILE B 1 592 ? 118.392 145.346 158.020 1.00 109.04 ? 592 ILE B CD1 1 
ATOM   6092 N N   . ALA B 1 593 ? 121.495 149.405 155.578 1.00 95.90  ? 593 ALA B N   1 
ATOM   6093 C CA  . ALA B 1 593 ? 121.681 150.440 154.565 1.00 90.85  ? 593 ALA B CA  1 
ATOM   6094 C C   . ALA B 1 593 ? 123.102 150.433 154.021 1.00 84.05  ? 593 ALA B C   1 
ATOM   6095 O O   . ALA B 1 593 ? 123.311 150.500 152.803 1.00 80.46  ? 593 ALA B O   1 
ATOM   6096 C CB  . ALA B 1 593 ? 121.342 151.810 155.148 1.00 88.06  ? 593 ALA B CB  1 
ATOM   6097 N N   . THR B 1 594 ? 124.092 150.344 154.910 1.00 83.53  ? 594 THR B N   1 
ATOM   6098 C CA  . THR B 1 594 ? 125.483 150.392 154.484 1.00 82.24  ? 594 THR B CA  1 
ATOM   6099 C C   . THR B 1 594 ? 125.862 149.164 153.673 1.00 78.92  ? 594 THR B C   1 
ATOM   6100 O O   . THR B 1 594 ? 126.756 149.237 152.826 1.00 74.93  ? 594 THR B O   1 
ATOM   6101 C CB  . THR B 1 594 ? 126.400 150.525 155.698 1.00 89.38  ? 594 THR B CB  1 
ATOM   6102 O OG1 . THR B 1 594 ? 125.911 151.566 156.553 1.00 92.74  ? 594 THR B OG1 1 
ATOM   6103 C CG2 . THR B 1 594 ? 127.814 150.866 155.262 1.00 90.25  ? 594 THR B CG2 1 
ATOM   6104 N N   . VAL B 1 595 ? 125.201 148.033 153.916 1.00 80.55  ? 595 VAL B N   1 
ATOM   6105 C CA  . VAL B 1 595 ? 125.487 146.842 153.126 1.00 77.27  ? 595 VAL B CA  1 
ATOM   6106 C C   . VAL B 1 595 ? 124.754 146.888 151.792 1.00 75.27  ? 595 VAL B C   1 
ATOM   6107 O O   . VAL B 1 595 ? 125.314 146.522 150.755 1.00 70.97  ? 595 VAL B O   1 
ATOM   6108 C CB  . VAL B 1 595 ? 125.139 145.574 153.924 1.00 77.45  ? 595 VAL B CB  1 
ATOM   6109 C CG1 . VAL B 1 595 ? 125.192 144.355 153.027 1.00 76.65  ? 595 VAL B CG1 1 
ATOM   6110 C CG2 . VAL B 1 595 ? 126.097 145.411 155.090 1.00 79.98  ? 595 VAL B CG2 1 
ATOM   6111 N N   . PHE B 1 596 ? 123.501 147.347 151.786 1.00 77.00  ? 596 PHE B N   1 
ATOM   6112 C CA  . PHE B 1 596 ? 122.703 147.307 150.568 1.00 74.82  ? 596 PHE B CA  1 
ATOM   6113 C C   . PHE B 1 596 ? 123.071 148.404 149.579 1.00 72.38  ? 596 PHE B C   1 
ATOM   6114 O O   . PHE B 1 596 ? 122.876 148.220 148.374 1.00 69.86  ? 596 PHE B O   1 
ATOM   6115 C CB  . PHE B 1 596 ? 121.214 147.391 150.907 1.00 73.23  ? 596 PHE B CB  1 
ATOM   6116 C CG  . PHE B 1 596 ? 120.601 146.070 151.270 1.00 77.19  ? 596 PHE B CG  1 
ATOM   6117 C CD1 . PHE B 1 596 ? 121.330 144.901 151.156 1.00 78.18  ? 596 PHE B CD1 1 
ATOM   6118 C CD2 . PHE B 1 596 ? 119.295 145.996 151.713 1.00 82.48  ? 596 PHE B CD2 1 
ATOM   6119 C CE1 . PHE B 1 596 ? 120.773 143.685 151.486 1.00 79.80  ? 596 PHE B CE1 1 
ATOM   6120 C CE2 . PHE B 1 596 ? 118.730 144.780 152.044 1.00 86.23  ? 596 PHE B CE2 1 
ATOM   6121 C CZ  . PHE B 1 596 ? 119.472 143.624 151.930 1.00 89.12  ? 596 PHE B CZ  1 
ATOM   6122 N N   . ALA B 1 597 ? 123.589 149.541 150.048 1.00 70.82  ? 597 ALA B N   1 
ATOM   6123 C CA  . ALA B 1 597 ? 123.907 150.625 149.122 1.00 64.93  ? 597 ALA B CA  1 
ATOM   6124 C C   . ALA B 1 597 ? 124.929 150.217 148.068 1.00 61.41  ? 597 ALA B C   1 
ATOM   6125 O O   . ALA B 1 597 ? 124.663 150.432 146.871 1.00 60.48  ? 597 ALA B O   1 
ATOM   6126 C CB  . ALA B 1 597 ? 124.354 151.861 149.909 1.00 70.59  ? 597 ALA B CB  1 
ATOM   6127 N N   . PRO B 1 598 ? 126.082 149.633 148.408 1.00 60.04  ? 598 PRO B N   1 
ATOM   6128 C CA  . PRO B 1 598 ? 126.939 149.088 147.346 1.00 57.61  ? 598 PRO B CA  1 
ATOM   6129 C C   . PRO B 1 598 ? 126.262 147.994 146.551 1.00 58.90  ? 598 PRO B C   1 
ATOM   6130 O O   . PRO B 1 598 ? 126.550 147.836 145.360 1.00 56.60  ? 598 PRO B O   1 
ATOM   6131 C CB  . PRO B 1 598 ? 128.161 148.566 148.111 1.00 57.85  ? 598 PRO B CB  1 
ATOM   6132 C CG  . PRO B 1 598 ? 127.688 148.370 149.490 1.00 62.51  ? 598 PRO B CG  1 
ATOM   6133 C CD  . PRO B 1 598 ? 126.703 149.456 149.730 1.00 62.47  ? 598 PRO B CD  1 
ATOM   6134 N N   . LEU B 1 599 ? 125.358 147.234 147.170 1.00 60.37  ? 599 LEU B N   1 
ATOM   6135 C CA  . LEU B 1 599 ? 124.597 146.245 146.417 1.00 59.96  ? 599 LEU B CA  1 
ATOM   6136 C C   . LEU B 1 599 ? 123.664 146.913 145.413 1.00 61.15  ? 599 LEU B C   1 
ATOM   6137 O O   . LEU B 1 599 ? 123.498 146.420 144.293 1.00 56.71  ? 599 LEU B O   1 
ATOM   6138 C CB  . LEU B 1 599 ? 123.822 145.338 147.370 1.00 60.48  ? 599 LEU B CB  1 
ATOM   6139 C CG  . LEU B 1 599 ? 124.521 144.040 147.788 1.00 61.79  ? 599 LEU B CG  1 
ATOM   6140 C CD1 . LEU B 1 599 ? 124.851 143.184 146.579 1.00 55.00  ? 599 LEU B CD1 1 
ATOM   6141 C CD2 . LEU B 1 599 ? 125.776 144.321 148.583 1.00 61.18  ? 599 LEU B CD2 1 
ATOM   6142 N N   . GLU B 1 600 ? 123.050 148.038 145.787 1.00 63.16  ? 600 GLU B N   1 
ATOM   6143 C CA  . GLU B 1 600 ? 122.244 148.782 144.823 1.00 58.80  ? 600 GLU B CA  1 
ATOM   6144 C C   . GLU B 1 600 ? 123.102 149.317 143.687 1.00 56.07  ? 600 GLU B C   1 
ATOM   6145 O O   . GLU B 1 600 ? 122.697 149.276 142.521 1.00 55.30  ? 600 GLU B O   1 
ATOM   6146 C CB  . GLU B 1 600 ? 121.510 149.930 145.511 1.00 62.81  ? 600 GLU B CB  1 
ATOM   6147 C CG  . GLU B 1 600 ? 120.404 149.491 146.440 1.00 71.24  ? 600 GLU B CG  1 
ATOM   6148 C CD  . GLU B 1 600 ? 119.707 150.661 147.098 1.00 76.69  ? 600 GLU B CD  1 
ATOM   6149 O OE1 . GLU B 1 600 ? 119.842 151.796 146.596 1.00 76.82  ? 600 GLU B OE1 1 
ATOM   6150 O OE2 . GLU B 1 600 ? 119.020 150.446 148.117 1.00 79.93  ? 600 GLU B OE2 1 
ATOM   6151 N N   . VAL B 1 601 ? 124.290 149.834 144.009 1.00 55.07  ? 601 VAL B N   1 
ATOM   6152 C CA  . VAL B 1 601 ? 125.185 150.325 142.965 1.00 49.52  ? 601 VAL B CA  1 
ATOM   6153 C C   . VAL B 1 601 ? 125.561 149.195 142.020 1.00 49.92  ? 601 VAL B C   1 
ATOM   6154 O O   . VAL B 1 601 ? 125.594 149.370 140.798 1.00 47.96  ? 601 VAL B O   1 
ATOM   6155 C CB  . VAL B 1 601 ? 126.431 150.977 143.589 1.00 47.42  ? 601 VAL B CB  1 
ATOM   6156 C CG1 . VAL B 1 601 ? 127.385 151.418 142.506 1.00 48.72  ? 601 VAL B CG1 1 
ATOM   6157 C CG2 . VAL B 1 601 ? 126.038 152.149 144.459 1.00 49.29  ? 601 VAL B CG2 1 
ATOM   6158 N N   . PHE B 1 602 ? 125.840 148.013 142.571 1.00 50.71  ? 602 PHE B N   1 
ATOM   6159 C CA  . PHE B 1 602 ? 126.176 146.856 141.749 1.00 44.37  ? 602 PHE B CA  1 
ATOM   6160 C C   . PHE B 1 602 ? 125.002 146.430 140.881 1.00 45.49  ? 602 PHE B C   1 
ATOM   6161 O O   . PHE B 1 602 ? 125.184 146.034 139.726 1.00 47.03  ? 602 PHE B O   1 
ATOM   6162 C CB  . PHE B 1 602 ? 126.621 145.700 142.641 1.00 44.22  ? 602 PHE B CB  1 
ATOM   6163 C CG  . PHE B 1 602 ? 126.887 144.433 141.894 1.00 41.69  ? 602 PHE B CG  1 
ATOM   6164 C CD1 . PHE B 1 602 ? 128.087 144.248 141.236 1.00 40.18  ? 602 PHE B CD1 1 
ATOM   6165 C CD2 . PHE B 1 602 ? 125.945 143.425 141.855 1.00 41.28  ? 602 PHE B CD2 1 
ATOM   6166 C CE1 . PHE B 1 602 ? 128.339 143.087 140.547 1.00 45.77  ? 602 PHE B CE1 1 
ATOM   6167 C CE2 . PHE B 1 602 ? 126.192 142.260 141.168 1.00 44.37  ? 602 PHE B CE2 1 
ATOM   6168 C CZ  . PHE B 1 602 ? 127.391 142.090 140.513 1.00 47.28  ? 602 PHE B CZ  1 
ATOM   6169 N N   . ARG B 1 603 ? 123.790 146.468 141.432 1.00 47.02  ? 603 ARG B N   1 
ATOM   6170 C CA  . ARG B 1 603 ? 122.618 146.079 140.658 1.00 47.51  ? 603 ARG B CA  1 
ATOM   6171 C C   . ARG B 1 603 ? 122.372 147.055 139.517 1.00 46.58  ? 603 ARG B C   1 
ATOM   6172 O O   . ARG B 1 603 ? 121.976 146.656 138.419 1.00 43.26  ? 603 ARG B O   1 
ATOM   6173 C CB  . ARG B 1 603 ? 121.399 145.976 141.571 1.00 46.79  ? 603 ARG B CB  1 
ATOM   6174 C CG  . ARG B 1 603 ? 120.223 145.246 140.955 1.00 45.83  ? 603 ARG B CG  1 
ATOM   6175 C CD  . ARG B 1 603 ? 119.270 146.218 140.331 1.00 55.58  ? 603 ARG B CD  1 
ATOM   6176 N NE  . ARG B 1 603 ? 118.939 147.272 141.276 1.00 57.21  ? 603 ARG B NE  1 
ATOM   6177 C CZ  . ARG B 1 603 ? 118.526 148.481 140.931 1.00 58.64  ? 603 ARG B CZ  1 
ATOM   6178 N NH1 . ARG B 1 603 ? 118.372 148.820 139.664 1.00 57.63  ? 603 ARG B NH1 1 
ATOM   6179 N NH2 . ARG B 1 603 ? 118.265 149.372 141.881 1.00 60.41  ? 603 ARG B NH2 1 
ATOM   6180 N N   . ARG B 1 604 ? 122.601 148.344 139.762 1.00 49.65  ? 604 ARG B N   1 
ATOM   6181 C CA  . ARG B 1 604 ? 122.531 149.331 138.689 1.00 46.03  ? 604 ARG B CA  1 
ATOM   6182 C C   . ARG B 1 604 ? 123.619 149.089 137.650 1.00 44.40  ? 604 ARG B C   1 
ATOM   6183 O O   . ARG B 1 604 ? 123.394 149.259 136.446 1.00 43.41  ? 604 ARG B O   1 
ATOM   6184 C CB  . ARG B 1 604 ? 122.640 150.733 139.278 1.00 44.38  ? 604 ARG B CB  1 
ATOM   6185 C CG  . ARG B 1 604 ? 122.648 151.842 138.262 1.00 43.95  ? 604 ARG B CG  1 
ATOM   6186 C CD  . ARG B 1 604 ? 121.366 151.871 137.468 1.00 45.31  ? 604 ARG B CD  1 
ATOM   6187 N NE  . ARG B 1 604 ? 120.197 151.933 138.332 1.00 46.86  ? 604 ARG B NE  1 
ATOM   6188 C CZ  . ARG B 1 604 ? 118.949 151.952 137.890 1.00 48.08  ? 604 ARG B CZ  1 
ATOM   6189 N NH1 . ARG B 1 604 ? 118.675 151.940 136.598 1.00 42.99  ? 604 ARG B NH1 1 
ATOM   6190 N NH2 . ARG B 1 604 ? 117.951 151.987 138.768 1.00 56.56  ? 604 ARG B NH2 1 
ATOM   6191 N N   . PHE B 1 605 ? 124.807 148.690 138.106 1.00 45.90  ? 605 PHE B N   1 
ATOM   6192 C CA  . PHE B 1 605 ? 125.891 148.335 137.197 1.00 43.42  ? 605 PHE B CA  1 
ATOM   6193 C C   . PHE B 1 605 ? 125.492 147.171 136.296 1.00 47.62  ? 605 PHE B C   1 
ATOM   6194 O O   . PHE B 1 605 ? 125.777 147.180 135.094 1.00 51.17  ? 605 PHE B O   1 
ATOM   6195 C CB  . PHE B 1 605 ? 127.142 148.012 138.018 1.00 38.62  ? 605 PHE B CB  1 
ATOM   6196 C CG  . PHE B 1 605 ? 128.041 146.982 137.405 1.00 41.42  ? 605 PHE B CG  1 
ATOM   6197 C CD1 . PHE B 1 605 ? 128.843 147.292 136.332 1.00 42.45  ? 605 PHE B CD1 1 
ATOM   6198 C CD2 . PHE B 1 605 ? 128.117 145.712 137.935 1.00 40.17  ? 605 PHE B CD2 1 
ATOM   6199 C CE1 . PHE B 1 605 ? 129.676 146.348 135.783 1.00 40.81  ? 605 PHE B CE1 1 
ATOM   6200 C CE2 . PHE B 1 605 ? 128.950 144.767 137.387 1.00 32.64  ? 605 PHE B CE2 1 
ATOM   6201 C CZ  . PHE B 1 605 ? 129.727 145.087 136.311 1.00 36.12  ? 605 PHE B CZ  1 
ATOM   6202 N N   . VAL B 1 606 ? 124.827 146.165 136.862 1.00 44.56  ? 606 VAL B N   1 
ATOM   6203 C CA  . VAL B 1 606 ? 124.313 145.055 136.063 1.00 41.32  ? 606 VAL B CA  1 
ATOM   6204 C C   . VAL B 1 606 ? 123.233 145.543 135.103 1.00 47.67  ? 606 VAL B C   1 
ATOM   6205 O O   . VAL B 1 606 ? 123.212 145.172 133.925 1.00 51.88  ? 606 VAL B O   1 
ATOM   6206 C CB  . VAL B 1 606 ? 123.789 143.938 136.981 1.00 38.16  ? 606 VAL B CB  1 
ATOM   6207 C CG1 . VAL B 1 606 ? 123.068 142.882 136.175 1.00 41.85  ? 606 VAL B CG1 1 
ATOM   6208 C CG2 . VAL B 1 606 ? 124.929 143.319 137.753 1.00 40.69  ? 606 VAL B CG2 1 
ATOM   6209 N N   . TRP B 1 607 ? 122.323 146.388 135.593 1.00 47.36  ? 607 TRP B N   1 
ATOM   6210 C CA  . TRP B 1 607 ? 121.229 146.895 134.770 1.00 46.13  ? 607 TRP B CA  1 
ATOM   6211 C C   . TRP B 1 607 ? 121.738 147.667 133.563 1.00 51.84  ? 607 TRP B C   1 
ATOM   6212 O O   . TRP B 1 607 ? 121.078 147.685 132.518 1.00 52.91  ? 607 TRP B O   1 
ATOM   6213 C CB  . TRP B 1 607 ? 120.321 147.779 135.623 1.00 46.90  ? 607 TRP B CB  1 
ATOM   6214 C CG  . TRP B 1 607 ? 119.284 148.572 134.872 1.00 49.46  ? 607 TRP B CG  1 
ATOM   6215 C CD1 . TRP B 1 607 ? 118.000 148.201 134.623 1.00 57.40  ? 607 TRP B CD1 1 
ATOM   6216 C CD2 . TRP B 1 607 ? 119.435 149.883 134.313 1.00 50.56  ? 607 TRP B CD2 1 
ATOM   6217 N NE1 . TRP B 1 607 ? 117.346 149.187 133.929 1.00 58.61  ? 607 TRP B NE1 1 
ATOM   6218 C CE2 . TRP B 1 607 ? 118.207 150.231 133.728 1.00 54.59  ? 607 TRP B CE2 1 
ATOM   6219 C CE3 . TRP B 1 607 ? 120.492 150.791 134.245 1.00 50.79  ? 607 TRP B CE3 1 
ATOM   6220 C CZ2 . TRP B 1 607 ? 118.006 151.444 133.086 1.00 53.73  ? 607 TRP B CZ2 1 
ATOM   6221 C CZ3 . TRP B 1 607 ? 120.290 151.995 133.606 1.00 48.64  ? 607 TRP B CZ3 1 
ATOM   6222 C CH2 . TRP B 1 607 ? 119.059 152.309 133.033 1.00 53.58  ? 607 TRP B CH2 1 
ATOM   6223 N N   . ASN B 1 608 ? 122.887 148.333 133.700 1.00 52.43  ? 608 ASN B N   1 
ATOM   6224 C CA  . ASN B 1 608 ? 123.414 149.138 132.601 1.00 49.02  ? 608 ASN B CA  1 
ATOM   6225 C C   . ASN B 1 608 ? 123.711 148.289 131.374 1.00 50.99  ? 608 ASN B C   1 
ATOM   6226 O O   . ASN B 1 608 ? 123.378 148.680 130.246 1.00 57.96  ? 608 ASN B O   1 
ATOM   6227 C CB  . ASN B 1 608 ? 124.670 149.877 133.048 1.00 43.85  ? 608 ASN B CB  1 
ATOM   6228 C CG  . ASN B 1 608 ? 124.357 151.101 133.868 1.00 46.63  ? 608 ASN B CG  1 
ATOM   6229 O OD1 . ASN B 1 608 ? 124.182 152.190 133.327 1.00 51.74  ? 608 ASN B OD1 1 
ATOM   6230 N ND2 . ASN B 1 608 ? 124.281 150.934 135.182 1.00 43.64  ? 608 ASN B ND2 1 
ATOM   6231 N N   . PHE B 1 609 ? 124.330 147.121 131.575 1.00 46.96  ? 609 PHE B N   1 
ATOM   6232 C CA  . PHE B 1 609 ? 124.681 146.255 130.454 1.00 53.43  ? 609 PHE B CA  1 
ATOM   6233 C C   . PHE B 1 609 ? 123.469 145.974 129.587 1.00 62.11  ? 609 PHE B C   1 
ATOM   6234 O O   . PHE B 1 609 ? 123.486 146.195 128.372 1.00 67.74  ? 609 PHE B O   1 
ATOM   6235 C CB  . PHE B 1 609 ? 125.254 144.931 130.959 1.00 51.90  ? 609 PHE B CB  1 
ATOM   6236 C CG  . PHE B 1 609 ? 126.662 145.014 131.456 1.00 50.58  ? 609 PHE B CG  1 
ATOM   6237 C CD1 . PHE B 1 609 ? 127.687 145.398 130.617 1.00 54.15  ? 609 PHE B CD1 1 
ATOM   6238 C CD2 . PHE B 1 609 ? 126.965 144.667 132.755 1.00 43.85  ? 609 PHE B CD2 1 
ATOM   6239 C CE1 . PHE B 1 609 ? 128.982 145.460 131.075 1.00 49.56  ? 609 PHE B CE1 1 
ATOM   6240 C CE2 . PHE B 1 609 ? 128.255 144.724 133.212 1.00 38.17  ? 609 PHE B CE2 1 
ATOM   6241 C CZ  . PHE B 1 609 ? 129.264 145.121 132.373 1.00 41.12  ? 609 PHE B CZ  1 
ATOM   6242 N N   . PHE B 1 610 ? 122.389 145.515 130.210 1.00 58.93  ? 610 PHE B N   1 
ATOM   6243 C CA  . PHE B 1 610 ? 121.244 145.045 129.451 1.00 59.51  ? 610 PHE B CA  1 
ATOM   6244 C C   . PHE B 1 610 ? 120.352 146.185 128.985 1.00 60.61  ? 610 PHE B C   1 
ATOM   6245 O O   . PHE B 1 610 ? 119.744 146.079 127.916 1.00 68.95  ? 610 PHE B O   1 
ATOM   6246 C CB  . PHE B 1 610 ? 120.484 144.022 130.285 1.00 59.14  ? 610 PHE B CB  1 
ATOM   6247 C CG  . PHE B 1 610 ? 121.374 142.959 130.848 1.00 60.18  ? 610 PHE B CG  1 
ATOM   6248 C CD1 . PHE B 1 610 ? 121.876 141.963 130.035 1.00 61.97  ? 610 PHE B CD1 1 
ATOM   6249 C CD2 . PHE B 1 610 ? 121.747 142.980 132.177 1.00 59.69  ? 610 PHE B CD2 1 
ATOM   6250 C CE1 . PHE B 1 610 ? 122.713 140.998 130.543 1.00 61.95  ? 610 PHE B CE1 1 
ATOM   6251 C CE2 . PHE B 1 610 ? 122.583 142.015 132.688 1.00 57.45  ? 610 PHE B CE2 1 
ATOM   6252 C CZ  . PHE B 1 610 ? 123.066 141.023 131.871 1.00 57.44  ? 610 PHE B CZ  1 
ATOM   6253 N N   . ARG B 1 611 ? 120.289 147.294 129.726 1.00 56.15  ? 611 ARG B N   1 
ATOM   6254 C CA  . ARG B 1 611 ? 119.579 148.457 129.210 1.00 56.28  ? 611 ARG B CA  1 
ATOM   6255 C C   . ARG B 1 611 ? 120.228 148.961 127.932 1.00 61.91  ? 611 ARG B C   1 
ATOM   6256 O O   . ARG B 1 611 ? 119.543 149.242 126.941 1.00 64.88  ? 611 ARG B O   1 
ATOM   6257 C CB  . ARG B 1 611 ? 119.539 149.571 130.249 1.00 54.21  ? 611 ARG B CB  1 
ATOM   6258 C CG  . ARG B 1 611 ? 118.696 150.759 129.817 1.00 56.17  ? 611 ARG B CG  1 
ATOM   6259 C CD  . ARG B 1 611 ? 117.230 150.374 129.724 1.00 63.16  ? 611 ARG B CD  1 
ATOM   6260 N NE  . ARG B 1 611 ? 116.343 151.531 129.707 1.00 68.06  ? 611 ARG B NE  1 
ATOM   6261 C CZ  . ARG B 1 611 ? 115.866 152.089 128.605 1.00 74.48  ? 611 ARG B CZ  1 
ATOM   6262 N NH1 . ARG B 1 611 ? 116.181 151.629 127.408 1.00 79.14  ? 611 ARG B NH1 1 
ATOM   6263 N NH2 . ARG B 1 611 ? 115.050 153.134 128.709 1.00 70.12  ? 611 ARG B NH2 1 
ATOM   6264 N N   . LEU B 1 612 ? 121.557 149.064 127.922 1.00 64.91  ? 612 LEU B N   1 
ATOM   6265 C CA  . LEU B 1 612 ? 122.211 149.544 126.713 1.00 67.69  ? 612 LEU B CA  1 
ATOM   6266 C C   . LEU B 1 612 ? 122.220 148.497 125.610 1.00 69.09  ? 612 LEU B C   1 
ATOM   6267 O O   . LEU B 1 612 ? 122.191 148.857 124.431 1.00 68.24  ? 612 LEU B O   1 
ATOM   6268 C CB  . LEU B 1 612 ? 123.628 150.022 127.025 1.00 61.89  ? 612 LEU B CB  1 
ATOM   6269 C CG  . LEU B 1 612 ? 123.615 151.518 127.327 1.00 56.35  ? 612 LEU B CG  1 
ATOM   6270 C CD1 . LEU B 1 612 ? 125.005 152.068 127.418 1.00 54.58  ? 612 LEU B CD1 1 
ATOM   6271 C CD2 . LEU B 1 612 ? 122.858 152.226 126.239 1.00 60.56  ? 612 LEU B CD2 1 
ATOM   6272 N N   . GLU B 1 613 ? 122.239 147.209 125.954 1.00 67.95  ? 613 GLU B N   1 
ATOM   6273 C CA  . GLU B 1 613 ? 122.069 146.192 124.925 1.00 72.09  ? 613 GLU B CA  1 
ATOM   6274 C C   . GLU B 1 613 ? 120.712 146.321 124.253 1.00 74.82  ? 613 GLU B C   1 
ATOM   6275 O O   . GLU B 1 613 ? 120.612 146.270 123.021 1.00 81.06  ? 613 GLU B O   1 
ATOM   6276 C CB  . GLU B 1 613 ? 122.228 144.797 125.521 1.00 71.04  ? 613 GLU B CB  1 
ATOM   6277 C CG  . GLU B 1 613 ? 121.902 143.695 124.537 1.00 80.40  ? 613 GLU B CG  1 
ATOM   6278 C CD  . GLU B 1 613 ? 121.978 142.318 125.153 1.00 85.94  ? 613 GLU B CD  1 
ATOM   6279 O OE1 . GLU B 1 613 ? 121.943 142.216 126.397 1.00 79.83  ? 613 GLU B OE1 1 
ATOM   6280 O OE2 . GLU B 1 613 ? 122.074 141.334 124.391 1.00 93.73  ? 613 GLU B OE2 1 
ATOM   6281 N N   . ASN B 1 614 ? 119.655 146.497 125.047 1.00 69.29  ? 614 ASN B N   1 
ATOM   6282 C CA  . ASN B 1 614 ? 118.335 146.692 124.467 1.00 69.61  ? 614 ASN B CA  1 
ATOM   6283 C C   . ASN B 1 614 ? 118.288 147.952 123.621 1.00 72.70  ? 614 ASN B C   1 
ATOM   6284 O O   . ASN B 1 614 ? 117.707 147.939 122.534 1.00 79.81  ? 614 ASN B O   1 
ATOM   6285 C CB  . ASN B 1 614 ? 117.275 146.747 125.564 1.00 70.56  ? 614 ASN B CB  1 
ATOM   6286 C CG  . ASN B 1 614 ? 115.881 146.479 125.037 1.00 71.90  ? 614 ASN B CG  1 
ATOM   6287 O OD1 . ASN B 1 614 ? 115.639 146.534 123.832 1.00 75.72  ? 614 ASN B OD1 1 
ATOM   6288 N ND2 . ASN B 1 614 ? 114.955 146.187 125.940 1.00 68.50  ? 614 ASN B ND2 1 
ATOM   6289 N N   . GLU B 1 615 ? 118.903 149.040 124.091 1.00 68.71  ? 615 GLU B N   1 
ATOM   6290 C CA  . GLU B 1 615 ? 118.946 150.264 123.298 1.00 69.16  ? 615 GLU B CA  1 
ATOM   6291 C C   . GLU B 1 615 ? 119.652 150.039 121.967 1.00 74.76  ? 615 GLU B C   1 
ATOM   6292 O O   . GLU B 1 615 ? 119.202 150.531 120.926 1.00 75.23  ? 615 GLU B O   1 
ATOM   6293 C CB  . GLU B 1 615 ? 119.640 151.371 124.084 1.00 68.09  ? 615 GLU B CB  1 
ATOM   6294 C CG  . GLU B 1 615 ? 118.804 151.954 125.199 1.00 69.04  ? 615 GLU B CG  1 
ATOM   6295 C CD  . GLU B 1 615 ? 117.754 152.912 124.689 1.00 74.06  ? 615 GLU B CD  1 
ATOM   6296 O OE1 . GLU B 1 615 ? 117.850 153.328 123.517 1.00 78.83  ? 615 GLU B OE1 1 
ATOM   6297 O OE2 . GLU B 1 615 ? 116.835 153.249 125.461 1.00 77.50  ? 615 GLU B OE2 1 
ATOM   6298 N N   . HIS B 1 616 ? 120.765 149.306 121.982 1.00 74.79  ? 616 HIS B N   1 
ATOM   6299 C CA  . HIS B 1 616 ? 121.501 149.040 120.751 1.00 73.93  ? 616 HIS B CA  1 
ATOM   6300 C C   . HIS B 1 616 ? 120.680 148.192 119.790 1.00 76.52  ? 616 HIS B C   1 
ATOM   6301 O O   . HIS B 1 616 ? 120.649 148.458 118.583 1.00 79.43  ? 616 HIS B O   1 
ATOM   6302 C CB  . HIS B 1 616 ? 122.830 148.356 121.075 1.00 70.89  ? 616 HIS B CB  1 
ATOM   6303 C CG  . HIS B 1 616 ? 123.652 148.028 119.867 1.00 73.70  ? 616 HIS B CG  1 
ATOM   6304 N ND1 . HIS B 1 616 ? 124.093 148.988 118.983 1.00 75.11  ? 616 HIS B ND1 1 
ATOM   6305 C CD2 . HIS B 1 616 ? 124.118 146.845 119.400 1.00 76.89  ? 616 HIS B CD2 1 
ATOM   6306 C CE1 . HIS B 1 616 ? 124.793 148.411 118.023 1.00 76.03  ? 616 HIS B CE1 1 
ATOM   6307 N NE2 . HIS B 1 616 ? 124.823 147.111 118.253 1.00 79.39  ? 616 HIS B NE2 1 
ATOM   6308 N N   . LEU B 1 617 ? 120.004 147.166 120.304 1.00 74.75  ? 617 LEU B N   1 
ATOM   6309 C CA  . LEU B 1 617 ? 119.283 146.242 119.438 1.00 75.45  ? 617 LEU B CA  1 
ATOM   6310 C C   . LEU B 1 617 ? 117.962 146.830 118.959 1.00 78.22  ? 617 LEU B C   1 
ATOM   6311 O O   . LEU B 1 617 ? 117.774 147.046 117.758 1.00 86.15  ? 617 LEU B O   1 
ATOM   6312 C CB  . LEU B 1 617 ? 119.042 144.918 120.162 1.00 80.23  ? 617 LEU B CB  1 
ATOM   6313 C CG  . LEU B 1 617 ? 120.300 144.115 120.488 1.00 85.24  ? 617 LEU B CG  1 
ATOM   6314 C CD1 . LEU B 1 617 ? 119.968 142.924 121.367 1.00 89.42  ? 617 LEU B CD1 1 
ATOM   6315 C CD2 . LEU B 1 617 ? 120.981 143.662 119.210 1.00 88.39  ? 617 LEU B CD2 1 
ATOM   6316 N N   . ASN B 1 618 ? 117.046 147.101 119.884 1.00 76.67  ? 618 ASN B N   1 
ATOM   6317 C CA  . ASN B 1 618 ? 115.737 147.641 119.530 1.00 76.63  ? 618 ASN B CA  1 
ATOM   6318 C C   . ASN B 1 618 ? 115.617 149.056 120.076 1.00 79.60  ? 618 ASN B C   1 
ATOM   6319 O O   . ASN B 1 618 ? 115.876 149.295 121.258 1.00 81.03  ? 618 ASN B O   1 
ATOM   6320 C CB  . ASN B 1 618 ? 114.633 146.748 120.086 1.00 76.04  ? 618 ASN B CB  1 
ATOM   6321 C CG  . ASN B 1 618 ? 115.038 145.292 120.150 1.00 81.75  ? 618 ASN B CG  1 
ATOM   6322 O OD1 . ASN B 1 618 ? 114.911 144.556 119.173 1.00 86.32  ? 618 ASN B OD1 1 
ATOM   6323 N ND2 . ASN B 1 618 ? 115.527 144.867 121.308 1.00 82.56  ? 618 ASN B ND2 1 
ATOM   6324 N N   . ASN B 1 619 ? 115.191 149.995 119.237 1.00 80.14  ? 619 ASN B N   1 
ATOM   6325 C CA  . ASN B 1 619 ? 115.213 151.390 119.654 1.00 80.10  ? 619 ASN B CA  1 
ATOM   6326 C C   . ASN B 1 619 ? 114.188 151.623 120.753 1.00 76.88  ? 619 ASN B C   1 
ATOM   6327 O O   . ASN B 1 619 ? 113.022 151.924 120.478 1.00 70.24  ? 619 ASN B O   1 
ATOM   6328 C CB  . ASN B 1 619 ? 114.946 152.308 118.462 1.00 84.08  ? 619 ASN B CB  1 
ATOM   6329 C CG  . ASN B 1 619 ? 115.004 153.772 118.832 1.00 88.55  ? 619 ASN B CG  1 
ATOM   6330 O OD1 . ASN B 1 619 ? 115.575 154.142 119.856 1.00 91.52  ? 619 ASN B OD1 1 
ATOM   6331 N ND2 . ASN B 1 619 ? 114.412 154.617 117.997 1.00 85.10  ? 619 ASN B ND2 1 
ATOM   6332 N N   . CYS B 1 620 ? 114.625 151.489 122.002 1.00 33.94  ? 620 CYS B N   1 
ATOM   6333 C CA  . CYS B 1 620 ? 113.735 151.640 123.141 1.00 39.09  ? 620 CYS B CA  1 
ATOM   6334 C C   . CYS B 1 620 ? 113.696 153.094 123.597 1.00 42.56  ? 620 CYS B C   1 
ATOM   6335 O O   . CYS B 1 620 ? 114.713 153.788 123.647 1.00 44.07  ? 620 CYS B O   1 
ATOM   6336 C CB  . CYS B 1 620 ? 114.188 150.741 124.290 1.00 45.07  ? 620 CYS B CB  1 
ATOM   6337 S SG  . CYS B 1 620 ? 113.245 150.939 125.815 1.00 51.88  ? 620 CYS B SG  1 
ATOM   6338 N N   . GLY B 1 621 ? 112.495 153.555 123.932 1.00 44.49  ? 621 GLY B N   1 
ATOM   6339 C CA  . GLY B 1 621 ? 112.315 154.916 124.396 1.00 39.75  ? 621 GLY B CA  1 
ATOM   6340 C C   . GLY B 1 621 ? 112.282 155.940 123.280 1.00 41.45  ? 621 GLY B C   1 
ATOM   6341 O O   . GLY B 1 621 ? 112.209 157.143 123.544 1.00 44.27  ? 621 GLY B O   1 
ATOM   6342 N N   . GLU B 1 622 ? 112.351 155.474 122.032 1.00 42.23  ? 622 GLU B N   1 
ATOM   6343 C CA  . GLU B 1 622 ? 112.240 156.328 120.853 1.00 44.83  ? 622 GLU B CA  1 
ATOM   6344 C C   . GLU B 1 622 ? 113.319 157.404 120.814 1.00 45.68  ? 622 GLU B C   1 
ATOM   6345 O O   . GLU B 1 622 ? 113.159 158.423 120.135 1.00 50.45  ? 622 GLU B O   1 
ATOM   6346 C CB  . GLU B 1 622 ? 110.858 156.983 120.792 1.00 47.44  ? 622 GLU B CB  1 
ATOM   6347 C CG  . GLU B 1 622 ? 109.698 156.021 120.968 1.00 51.79  ? 622 GLU B CG  1 
ATOM   6348 C CD  . GLU B 1 622 ? 108.407 156.731 121.319 1.00 60.81  ? 622 GLU B CD  1 
ATOM   6349 O OE1 . GLU B 1 622 ? 108.402 157.980 121.338 1.00 59.13  ? 622 GLU B OE1 1 
ATOM   6350 O OE2 . GLU B 1 622 ? 107.401 156.041 121.581 1.00 62.83  ? 622 GLU B OE2 1 
ATOM   6351 N N   . PHE B 1 623 ? 114.421 157.189 121.530 1.00 40.62  ? 623 PHE B N   1 
ATOM   6352 C CA  . PHE B 1 623 ? 115.512 158.154 121.547 1.00 38.10  ? 623 PHE B CA  1 
ATOM   6353 C C   . PHE B 1 623 ? 116.184 158.244 120.183 1.00 42.63  ? 623 PHE B C   1 
ATOM   6354 O O   . PHE B 1 623 ? 116.943 159.183 119.925 1.00 47.39  ? 623 PHE B O   1 
ATOM   6355 C CB  . PHE B 1 623 ? 116.539 157.785 122.618 1.00 40.54  ? 623 PHE B CB  1 
ATOM   6356 C CG  . PHE B 1 623 ? 116.021 157.896 124.023 1.00 38.49  ? 623 PHE B CG  1 
ATOM   6357 C CD1 . PHE B 1 623 ? 115.998 159.113 124.672 1.00 37.19  ? 623 PHE B CD1 1 
ATOM   6358 C CD2 . PHE B 1 623 ? 115.570 156.779 124.699 1.00 38.31  ? 623 PHE B CD2 1 
ATOM   6359 C CE1 . PHE B 1 623 ? 115.530 159.216 125.964 1.00 37.61  ? 623 PHE B CE1 1 
ATOM   6360 C CE2 . PHE B 1 623 ? 115.102 156.880 125.991 1.00 36.85  ? 623 PHE B CE2 1 
ATOM   6361 C CZ  . PHE B 1 623 ? 115.082 158.099 126.623 1.00 36.65  ? 623 PHE B CZ  1 
ATOM   6362 N N   . ARG B 1 624 ? 115.927 157.263 119.319 1.00 45.46  ? 624 ARG B N   1 
ATOM   6363 C CA  . ARG B 1 624 ? 116.503 157.201 117.974 1.00 46.97  ? 624 ARG B CA  1 
ATOM   6364 C C   . ARG B 1 624 ? 118.024 157.095 118.010 1.00 49.26  ? 624 ARG B C   1 
ATOM   6365 O O   . ARG B 1 624 ? 118.629 156.953 119.070 1.00 48.60  ? 624 ARG B O   1 
ATOM   6366 C CB  . ARG B 1 624 ? 116.084 158.417 117.142 1.00 46.95  ? 624 ARG B CB  1 
ATOM   6367 C CG  . ARG B 1 624 ? 114.625 158.413 116.717 1.00 50.81  ? 624 ARG B CG  1 
ATOM   6368 C CD  . ARG B 1 624 ? 114.338 157.325 115.690 1.00 59.01  ? 624 ARG B CD  1 
ATOM   6369 N NE  . ARG B 1 624 ? 115.006 157.573 114.417 1.00 57.95  ? 624 ARG B NE  1 
ATOM   6370 C CZ  . ARG B 1 624 ? 116.117 156.967 114.021 1.00 57.08  ? 624 ARG B CZ  1 
ATOM   6371 N NH1 . ARG B 1 624 ? 116.715 156.058 114.773 1.00 56.56  ? 624 ARG B NH1 1 
ATOM   6372 N NH2 . ARG B 1 624 ? 116.639 157.280 112.839 1.00 54.22  ? 624 ARG B NH2 1 
HETATM 6373 O O12 . PC1 C 2 .   ? 168.225 137.207 128.412 1.00 75.79  ? 801 PC1 A O12 1 
HETATM 6374 P P   . PC1 C 2 .   ? 166.735 137.176 128.433 1.00 86.66  ? 801 PC1 A P   1 
HETATM 6375 O O14 . PC1 C 2 .   ? 165.875 137.949 127.491 1.00 78.69  ? 801 PC1 A O14 1 
HETATM 6376 O O13 . PC1 C 2 .   ? 166.209 135.624 128.271 1.00 79.59  ? 801 PC1 A O13 1 
HETATM 6377 C C11 . PC1 C 2 .   ? 165.729 135.217 127.016 1.00 81.63  ? 801 PC1 A C11 1 
HETATM 6378 C C12 . PC1 C 2 .   ? 166.512 133.947 126.721 1.00 85.89  ? 801 PC1 A C12 1 
HETATM 6379 N N   . PC1 C 2 .   ? 166.675 133.606 125.273 1.00 83.76  ? 801 PC1 A N   1 
HETATM 6380 C C13 . PC1 C 2 .   ? 167.794 132.645 125.082 1.00 78.95  ? 801 PC1 A C13 1 
HETATM 6381 C C14 . PC1 C 2 .   ? 165.408 132.964 124.823 1.00 84.70  ? 801 PC1 A C14 1 
HETATM 6382 C C15 . PC1 C 2 .   ? 166.916 134.825 124.453 1.00 78.77  ? 801 PC1 A C15 1 
HETATM 6383 O O11 . PC1 C 2 .   ? 166.327 137.483 129.990 1.00 74.16  ? 801 PC1 A O11 1 
HETATM 6384 C C1  . PC1 C 2 .   ? 167.175 137.037 131.023 1.00 66.83  ? 801 PC1 A C1  1 
HETATM 6385 C C2  . PC1 C 2 .   ? 167.265 138.127 132.070 1.00 62.66  ? 801 PC1 A C2  1 
HETATM 6386 O O21 . PC1 C 2 .   ? 166.195 138.044 133.014 1.00 55.58  ? 801 PC1 A O21 1 
HETATM 6387 C C21 . PC1 C 2 .   ? 166.375 137.382 134.153 1.00 53.21  ? 801 PC1 A C21 1 
HETATM 6388 O O22 . PC1 C 2 .   ? 167.335 136.692 134.367 1.00 57.43  ? 801 PC1 A O22 1 
HETATM 6389 C C22 . PC1 C 2 .   ? 165.242 137.618 135.111 1.00 48.94  ? 801 PC1 A C22 1 
HETATM 6390 C C23 . PC1 C 2 .   ? 164.769 136.374 135.844 1.00 45.81  ? 801 PC1 A C23 1 
HETATM 6391 C C24 . PC1 C 2 .   ? 165.558 136.120 137.121 1.00 41.54  ? 801 PC1 A C24 1 
HETATM 6392 C C25 . PC1 C 2 .   ? 165.194 137.074 138.247 1.00 42.73  ? 801 PC1 A C25 1 
HETATM 6393 C C26 . PC1 C 2 .   ? 165.863 136.712 139.564 1.00 48.82  ? 801 PC1 A C26 1 
HETATM 6394 C C27 . PC1 C 2 .   ? 165.332 135.425 140.178 1.00 55.89  ? 801 PC1 A C27 1 
HETATM 6395 C C28 . PC1 C 2 .   ? 166.058 135.027 141.457 1.00 59.62  ? 801 PC1 A C28 1 
HETATM 6396 C C29 . PC1 C 2 .   ? 167.515 134.637 141.238 1.00 60.26  ? 801 PC1 A C29 1 
HETATM 6397 C C2A . PC1 C 2 .   ? 168.159 133.979 142.452 1.00 72.25  ? 801 PC1 A C2A 1 
HETATM 6398 C C2B . PC1 C 2 .   ? 168.208 134.873 143.684 1.00 69.94  ? 801 PC1 A C2B 1 
HETATM 6399 C C2C . PC1 C 2 .   ? 169.094 134.337 144.802 1.00 68.73  ? 801 PC1 A C2C 1 
HETATM 6400 C C2D . PC1 C 2 .   ? 168.445 134.444 146.175 1.00 74.38  ? 801 PC1 A C2D 1 
HETATM 6401 C C2E . PC1 C 2 .   ? 169.445 134.532 147.321 1.00 74.75  ? 801 PC1 A C2E 1 
HETATM 6402 C C2F . PC1 C 2 .   ? 170.231 135.837 147.332 1.00 64.90  ? 801 PC1 A C2F 1 
HETATM 6403 C C2G . PC1 C 2 .   ? 170.110 136.629 148.629 1.00 67.25  ? 801 PC1 A C2G 1 
HETATM 6404 C C2H . PC1 C 2 .   ? 170.614 135.888 149.861 1.00 69.74  ? 801 PC1 A C2H 1 
HETATM 6405 C C2I . PC1 C 2 .   ? 170.887 136.809 151.042 1.00 68.23  ? 801 PC1 A C2I 1 
HETATM 6406 C C3  . PC1 C 2 .   ? 167.166 139.500 131.437 1.00 67.68  ? 801 PC1 A C3  1 
HETATM 6407 O O31 . PC1 C 2 .   ? 168.257 139.657 130.532 1.00 69.64  ? 801 PC1 A O31 1 
HETATM 6408 C C31 . PC1 C 2 .   ? 169.115 140.657 130.719 1.00 56.53  ? 801 PC1 A C31 1 
HETATM 6409 O O32 . PC1 C 2 .   ? 168.926 141.783 130.339 1.00 43.55  ? 801 PC1 A O32 1 
HETATM 6410 C C32 . PC1 C 2 .   ? 170.341 140.192 131.444 1.00 57.35  ? 801 PC1 A C32 1 
HETATM 6411 C C33 . PC1 C 2 .   ? 170.212 140.212 132.958 1.00 52.88  ? 801 PC1 A C33 1 
HETATM 6412 C C34 . PC1 C 2 .   ? 171.030 139.094 133.582 1.00 49.82  ? 801 PC1 A C34 1 
HETATM 6413 C C35 . PC1 C 2 .   ? 171.086 139.173 135.099 1.00 45.15  ? 801 PC1 A C35 1 
HETATM 6414 C C36 . PC1 C 2 .   ? 169.715 139.062 135.747 1.00 44.89  ? 801 PC1 A C36 1 
HETATM 6415 C C37 . PC1 C 2 .   ? 169.796 138.779 137.239 1.00 45.87  ? 801 PC1 A C37 1 
HETATM 6416 C C38 . PC1 C 2 .   ? 171.039 137.983 137.610 1.00 45.67  ? 801 PC1 A C38 1 
HETATM 6417 C C39 . PC1 C 2 .   ? 171.163 137.697 139.098 1.00 47.29  ? 801 PC1 A C39 1 
HETATM 6418 C C3A . PC1 C 2 .   ? 172.602 137.440 139.521 1.00 51.45  ? 801 PC1 A C3A 1 
HETATM 6419 C C3B . PC1 C 2 .   ? 172.742 137.059 140.986 1.00 56.39  ? 801 PC1 A C3B 1 
HETATM 6420 C C3C . PC1 C 2 .   ? 172.008 135.774 141.338 1.00 57.28  ? 801 PC1 A C3C 1 
HETATM 6421 C C3D . PC1 C 2 .   ? 172.321 135.276 142.741 1.00 63.62  ? 801 PC1 A C3D 1 
HETATM 6422 C C3E . PC1 C 2 .   ? 173.814 135.092 142.976 1.00 71.51  ? 801 PC1 A C3E 1 
HETATM 6423 C C3F . PC1 C 2 .   ? 174.436 133.988 142.129 1.00 74.34  ? 801 PC1 A C3F 1 
HETATM 6424 C C3G . PC1 C 2 .   ? 174.291 132.607 142.753 1.00 84.21  ? 801 PC1 A C3G 1 
HETATM 6425 C C3H . PC1 C 2 .   ? 174.591 132.590 144.246 1.00 86.01  ? 801 PC1 A C3H 1 
HETATM 6426 C C3I . PC1 C 2 .   ? 174.415 131.212 144.869 1.00 84.89  ? 801 PC1 A C3I 1 
HETATM 6427 O O12 . PC1 D 2 .   ? 158.252 151.982 125.222 1.00 96.29  ? 802 PC1 A O12 1 
HETATM 6428 P P   . PC1 D 2 .   ? 157.956 153.021 126.249 1.00 107.00 ? 802 PC1 A P   1 
HETATM 6429 O O14 . PC1 D 2 .   ? 158.994 153.932 126.808 1.00 90.27  ? 802 PC1 A O14 1 
HETATM 6430 O O13 . PC1 D 2 .   ? 156.769 154.038 125.714 1.00 109.64 ? 802 PC1 A O13 1 
HETATM 6431 C C11 . PC1 D 2 .   ? 155.846 153.601 124.745 1.00 107.32 ? 802 PC1 A C11 1 
HETATM 6432 C C12 . PC1 D 2 .   ? 156.462 153.996 123.409 1.00 114.76 ? 802 PC1 A C12 1 
HETATM 6433 N N   . PC1 D 2 .   ? 155.630 153.702 122.197 1.00 123.32 ? 802 PC1 A N   1 
HETATM 6434 C C13 . PC1 D 2 .   ? 154.487 154.649 122.089 1.00 124.91 ? 802 PC1 A C13 1 
HETATM 6435 C C14 . PC1 D 2 .   ? 156.506 153.863 121.002 1.00 119.12 ? 802 PC1 A C14 1 
HETATM 6436 C C15 . PC1 D 2 .   ? 155.117 152.304 122.220 1.00 123.46 ? 802 PC1 A C15 1 
HETATM 6437 O O11 . PC1 D 2 .   ? 157.171 152.214 127.444 1.00 90.76  ? 802 PC1 A O11 1 
HETATM 6438 C C1  . PC1 D 2 .   ? 156.242 152.875 128.276 1.00 82.34  ? 802 PC1 A C1  1 
HETATM 6439 C C2  . PC1 D 2 .   ? 156.956 153.425 129.490 1.00 71.58  ? 802 PC1 A C2  1 
HETATM 6440 O O21 . PC1 D 2 .   ? 156.121 153.415 130.647 1.00 62.02  ? 802 PC1 A O21 1 
HETATM 6441 C C21 . PC1 D 2 .   ? 156.252 152.423 131.519 1.00 66.48  ? 802 PC1 A C21 1 
HETATM 6442 O O22 . PC1 D 2 .   ? 156.494 151.290 131.195 1.00 70.49  ? 802 PC1 A O22 1 
HETATM 6443 C C22 . PC1 D 2 .   ? 156.070 152.906 132.931 1.00 67.79  ? 802 PC1 A C22 1 
HETATM 6444 C C23 . PC1 D 2 .   ? 157.348 152.944 133.753 1.00 55.03  ? 802 PC1 A C23 1 
HETATM 6445 C C24 . PC1 D 2 .   ? 157.278 151.952 134.906 1.00 44.23  ? 802 PC1 A C24 1 
HETATM 6446 C C25 . PC1 D 2 .   ? 158.493 151.992 135.821 1.00 43.94  ? 802 PC1 A C25 1 
HETATM 6447 C C26 . PC1 D 2 .   ? 158.364 153.004 136.949 1.00 43.53  ? 802 PC1 A C26 1 
HETATM 6448 C C27 . PC1 D 2 .   ? 159.146 152.610 138.194 1.00 43.35  ? 802 PC1 A C27 1 
HETATM 6449 C C28 . PC1 D 2 .   ? 158.928 151.158 138.606 1.00 46.59  ? 802 PC1 A C28 1 
HETATM 6450 C C29 . PC1 D 2 .   ? 159.420 150.834 140.013 1.00 50.30  ? 802 PC1 A C29 1 
HETATM 6451 C C2A . PC1 D 2 .   ? 159.749 149.359 140.220 1.00 51.56  ? 802 PC1 A C2A 1 
HETATM 6452 C C2B . PC1 D 2 .   ? 159.428 148.839 141.619 1.00 44.68  ? 802 PC1 A C2B 1 
HETATM 6453 C C2C . PC1 D 2 .   ? 160.436 149.231 142.694 1.00 35.38  ? 802 PC1 A C2C 1 
HETATM 6454 C C2D . PC1 D 2 .   ? 161.443 148.133 143.017 1.00 37.71  ? 802 PC1 A C2D 1 
HETATM 6455 C C2E . PC1 D 2 .   ? 162.565 148.581 143.947 1.00 33.41  ? 802 PC1 A C2E 1 
HETATM 6456 C C2F . PC1 D 2 .   ? 163.442 149.681 143.362 1.00 33.64  ? 802 PC1 A C2F 1 
HETATM 6457 C C2G . PC1 D 2 .   ? 164.790 149.820 144.055 1.00 33.53  ? 802 PC1 A C2G 1 
HETATM 6458 C C2H . PC1 D 2 .   ? 165.720 150.811 143.370 1.00 32.13  ? 802 PC1 A C2H 1 
HETATM 6459 C C2I . PC1 D 2 .   ? 165.191 152.237 143.381 1.00 31.03  ? 802 PC1 A C2I 1 
HETATM 6460 C C3  . PC1 D 2 .   ? 157.345 154.870 129.307 1.00 72.28  ? 802 PC1 A C3  1 
HETATM 6461 O O31 . PC1 D 2 .   ? 158.246 155.155 130.365 1.00 71.40  ? 802 PC1 A O31 1 
HETATM 6462 C C31 . PC1 D 2 .   ? 159.539 155.098 130.085 1.00 66.82  ? 802 PC1 A C31 1 
HETATM 6463 O O32 . PC1 D 2 .   ? 160.013 155.617 129.108 1.00 69.00  ? 802 PC1 A O32 1 
HETATM 6464 C C32 . PC1 D 2 .   ? 160.295 154.316 131.122 1.00 63.11  ? 802 PC1 A C32 1 
HETATM 6465 C C33 . PC1 D 2 .   ? 161.757 154.716 131.245 1.00 58.06  ? 802 PC1 A C33 1 
HETATM 6466 C C34 . PC1 D 2 .   ? 162.503 153.829 132.229 1.00 51.65  ? 802 PC1 A C34 1 
HETATM 6467 C C35 . PC1 D 2 .   ? 161.923 153.891 133.633 1.00 48.39  ? 802 PC1 A C35 1 
HETATM 6468 C C36 . PC1 D 2 .   ? 162.146 155.241 134.299 1.00 47.40  ? 802 PC1 A C36 1 
HETATM 6469 C C37 . PC1 D 2 .   ? 161.655 155.290 135.737 1.00 47.56  ? 802 PC1 A C37 1 
HETATM 6470 C C38 . PC1 D 2 .   ? 162.786 155.392 136.748 1.00 41.49  ? 802 PC1 A C38 1 
HETATM 6471 C C39 . PC1 D 2 .   ? 162.297 155.342 138.187 1.00 45.40  ? 802 PC1 A C39 1 
HETATM 6472 C C3A . PC1 D 2 .   ? 163.172 156.133 139.150 1.00 45.81  ? 802 PC1 A C3A 1 
HETATM 6473 C C3B . PC1 D 2 .   ? 162.581 156.236 140.548 1.00 45.03  ? 802 PC1 A C3B 1 
HETATM 6474 C C3C . PC1 D 2 .   ? 161.142 156.737 140.543 1.00 51.19  ? 802 PC1 A C3C 1 
HETATM 6475 C C3D . PC1 D 2 .   ? 160.996 158.201 140.149 1.00 53.71  ? 802 PC1 A C3D 1 
HETATM 6476 C C3E . PC1 D 2 .   ? 159.556 158.602 139.852 1.00 56.80  ? 802 PC1 A C3E 1 
HETATM 6477 C C3F . PC1 D 2 .   ? 159.426 159.970 139.193 1.00 63.97  ? 802 PC1 A C3F 1 
HETATM 6478 C C3G . PC1 D 2 .   ? 159.435 161.127 140.184 1.00 62.23  ? 802 PC1 A C3G 1 
HETATM 6479 C C3H . PC1 D 2 .   ? 158.177 161.209 141.040 1.00 68.90  ? 802 PC1 A C3H 1 
HETATM 6480 C C3I . PC1 D 2 .   ? 156.933 161.554 140.233 1.00 69.32  ? 802 PC1 A C3I 1 
HETATM 6481 P P   . PO4 E 3 .   ? 185.339 145.937 138.574 1.00 94.66  ? 803 PO4 A P   1 
HETATM 6482 O O1  . PO4 E 3 .   ? 186.662 145.301 139.109 1.00 80.68  ? 803 PO4 A O1  1 
HETATM 6483 O O2  . PO4 E 3 .   ? 185.483 147.495 138.555 1.00 78.14  ? 803 PO4 A O2  1 
HETATM 6484 O O3  . PO4 E 3 .   ? 184.152 145.520 139.510 1.00 74.51  ? 803 PO4 A O3  1 
HETATM 6485 O O4  . PO4 E 3 .   ? 185.052 145.438 137.117 1.00 75.92  ? 803 PO4 A O4  1 
HETATM 6486 O O12 . PC1 F 2 .   ? 132.859 161.435 126.492 1.00 92.67  ? 801 PC1 B O12 1 
HETATM 6487 P P   . PC1 F 2 .   ? 133.884 162.114 127.334 1.00 100.65 ? 801 PC1 B P   1 
HETATM 6488 O O14 . PC1 F 2 .   ? 135.351 161.957 127.116 1.00 98.18  ? 801 PC1 B O14 1 
HETATM 6489 O O13 . PC1 F 2 .   ? 133.629 163.745 127.321 1.00 86.40  ? 801 PC1 B O13 1 
HETATM 6490 C C11 . PC1 F 2 .   ? 132.506 164.263 126.651 1.00 90.84  ? 801 PC1 B C11 1 
HETATM 6491 C C12 . PC1 F 2 .   ? 132.964 164.461 125.213 1.00 95.57  ? 801 PC1 B C12 1 
HETATM 6492 N N   . PC1 F 2 .   ? 132.306 165.590 124.478 1.00 98.60  ? 801 PC1 B N   1 
HETATM 6493 C C13 . PC1 F 2 .   ? 130.902 165.256 124.118 1.00 96.09  ? 801 PC1 B C13 1 
HETATM 6494 C C14 . PC1 F 2 .   ? 133.086 165.825 123.231 1.00 105.74 ? 801 PC1 B C14 1 
HETATM 6495 C C15 . PC1 F 2 .   ? 132.323 166.841 125.286 1.00 92.07  ? 801 PC1 B C15 1 
HETATM 6496 O O11 . PC1 F 2 .   ? 133.491 161.730 128.883 1.00 82.87  ? 801 PC1 B O11 1 
HETATM 6497 C C1  . PC1 F 2 .   ? 132.156 161.817 129.328 1.00 71.90  ? 801 PC1 B C1  1 
HETATM 6498 C C2  . PC1 F 2 .   ? 131.902 160.712 130.333 1.00 70.14  ? 801 PC1 B C2  1 
HETATM 6499 O O21 . PC1 F 2 .   ? 132.735 160.827 131.489 1.00 68.20  ? 801 PC1 B O21 1 
HETATM 6500 C C21 . PC1 F 2 .   ? 132.286 161.479 132.558 1.00 67.10  ? 801 PC1 B C21 1 
HETATM 6501 O O22 . PC1 F 2 .   ? 131.260 162.105 132.561 1.00 68.34  ? 801 PC1 B O22 1 
HETATM 6502 C C22 . PC1 F 2 .   ? 133.215 161.336 133.733 1.00 63.81  ? 801 PC1 B C22 1 
HETATM 6503 C C23 . PC1 F 2 .   ? 133.494 162.643 134.456 1.00 56.96  ? 801 PC1 B C23 1 
HETATM 6504 C C24 . PC1 F 2 .   ? 134.303 162.434 135.729 1.00 53.84  ? 801 PC1 B C24 1 
HETATM 6505 C C25 . PC1 F 2 .   ? 133.520 161.726 136.825 1.00 53.09  ? 801 PC1 B C25 1 
HETATM 6506 C C26 . PC1 F 2 .   ? 133.154 162.641 137.984 1.00 50.57  ? 801 PC1 B C26 1 
HETATM 6507 C C27 . PC1 F 2 .   ? 134.249 162.773 139.031 1.00 52.08  ? 801 PC1 B C27 1 
HETATM 6508 C C28 . PC1 F 2 .   ? 133.873 163.711 140.169 1.00 57.92  ? 801 PC1 B C28 1 
HETATM 6509 C C29 . PC1 F 2 .   ? 132.456 163.512 140.695 1.00 63.63  ? 801 PC1 B C29 1 
HETATM 6510 C C2A . PC1 F 2 .   ? 132.168 164.338 141.945 1.00 71.49  ? 801 PC1 B C2A 1 
HETATM 6511 C C2B . PC1 F 2 .   ? 130.688 164.494 142.273 1.00 67.32  ? 801 PC1 B C2B 1 
HETATM 6512 C C2C . PC1 F 2 .   ? 130.423 165.525 143.363 1.00 72.11  ? 801 PC1 B C2C 1 
HETATM 6513 C C2D . PC1 F 2 .   ? 130.542 164.977 144.781 1.00 76.87  ? 801 PC1 B C2D 1 
HETATM 6514 C C2E . PC1 F 2 .   ? 129.256 164.332 145.283 1.00 85.84  ? 801 PC1 B C2E 1 
HETATM 6515 C C2F . PC1 F 2 .   ? 128.987 164.543 146.770 1.00 87.60  ? 801 PC1 B C2F 1 
HETATM 6516 C C2G . PC1 F 2 .   ? 129.399 163.360 147.638 1.00 85.14  ? 801 PC1 B C2G 1 
HETATM 6517 C C2H . PC1 F 2 .   ? 128.679 163.306 148.981 1.00 80.50  ? 801 PC1 B C2H 1 
HETATM 6518 C C2I . PC1 F 2 .   ? 128.781 164.600 149.775 1.00 82.04  ? 801 PC1 B C2I 1 
HETATM 6519 C C3  . PC1 F 2 .   ? 132.211 159.356 129.743 1.00 73.54  ? 801 PC1 B C3  1 
HETATM 6520 O O31 . PC1 F 2 .   ? 131.157 159.025 128.847 1.00 73.32  ? 801 PC1 B O31 1 
HETATM 6521 C C31 . PC1 F 2 .   ? 130.567 157.842 128.991 1.00 66.81  ? 801 PC1 B C31 1 
HETATM 6522 O O32 . PC1 F 2 .   ? 130.973 156.833 128.474 1.00 65.56  ? 801 PC1 B O32 1 
HETATM 6523 C C32 . PC1 F 2 .   ? 129.350 157.939 129.863 1.00 61.97  ? 801 PC1 B C32 1 
HETATM 6524 C C33 . PC1 F 2 .   ? 129.541 157.357 131.253 1.00 59.23  ? 801 PC1 B C33 1 
HETATM 6525 C C34 . PC1 F 2 .   ? 129.812 158.457 132.268 1.00 56.96  ? 801 PC1 B C34 1 
HETATM 6526 C C35 . PC1 F 2 .   ? 128.648 159.420 132.458 1.00 53.59  ? 801 PC1 B C35 1 
HETATM 6527 C C36 . PC1 F 2 .   ? 128.754 160.208 133.758 1.00 50.56  ? 801 PC1 B C36 1 
HETATM 6528 C C37 . PC1 F 2 .   ? 129.409 159.424 134.883 1.00 49.09  ? 801 PC1 B C37 1 
HETATM 6529 C C38 . PC1 F 2 .   ? 129.592 160.240 136.153 1.00 53.96  ? 801 PC1 B C38 1 
HETATM 6530 C C39 . PC1 F 2 .   ? 128.313 160.470 136.943 1.00 57.43  ? 801 PC1 B C39 1 
HETATM 6531 C C3A . PC1 F 2 .   ? 128.596 160.750 138.413 1.00 64.53  ? 801 PC1 B C3A 1 
HETATM 6532 C C3B . PC1 F 2 .   ? 127.770 161.888 138.993 1.00 67.90  ? 801 PC1 B C3B 1 
HETATM 6533 C C3C . PC1 F 2 .   ? 128.012 162.093 140.483 1.00 68.69  ? 801 PC1 B C3C 1 
HETATM 6534 C C3D . PC1 F 2 .   ? 126.893 162.852 141.182 1.00 69.78  ? 801 PC1 B C3D 1 
HETATM 6535 C C3E . PC1 F 2 .   ? 127.005 162.810 142.700 1.00 72.82  ? 801 PC1 B C3E 1 
HETATM 6536 C C3F . PC1 F 2 .   ? 125.678 162.565 143.407 1.00 74.51  ? 801 PC1 B C3F 1 
HETATM 6537 C C3G . PC1 F 2 .   ? 124.843 163.829 143.568 1.00 78.89  ? 801 PC1 B C3G 1 
HETATM 6538 C C3H . PC1 F 2 .   ? 125.547 164.921 144.363 1.00 83.03  ? 801 PC1 B C3H 1 
HETATM 6539 C C3I . PC1 F 2 .   ? 124.725 166.199 144.465 1.00 83.25  ? 801 PC1 B C3I 1 
HETATM 6540 O O12 . PC1 G 2 .   ? 143.562 148.364 126.977 1.00 99.91  ? 802 PC1 B O12 1 
HETATM 6541 P P   . PC1 G 2 .   ? 142.674 147.256 127.438 1.00 106.77 ? 802 PC1 B P   1 
HETATM 6542 O O14 . PC1 G 2 .   ? 141.371 147.478 128.126 1.00 85.46  ? 802 PC1 B O14 1 
HETATM 6543 O O13 . PC1 G 2 .   ? 142.303 146.281 126.156 1.00 99.44  ? 802 PC1 B O13 1 
HETATM 6544 C C11 . PC1 G 2 .   ? 143.120 145.175 125.859 1.00 94.38  ? 802 PC1 B C11 1 
HETATM 6545 C C12 . PC1 G 2 .   ? 144.366 145.762 125.211 1.00 94.71  ? 802 PC1 B C12 1 
HETATM 6546 N N   . PC1 G 2 .   ? 145.401 144.765 124.783 1.00 98.30  ? 802 PC1 B N   1 
HETATM 6547 C C13 . PC1 G 2 .   ? 145.639 143.739 125.835 1.00 99.04  ? 802 PC1 B C13 1 
HETATM 6548 C C14 . PC1 G 2 .   ? 144.894 144.087 123.556 1.00 98.54  ? 802 PC1 B C14 1 
HETATM 6549 C C15 . PC1 G 2 .   ? 146.687 145.445 124.460 1.00 95.97  ? 802 PC1 B C15 1 
HETATM 6550 O O11 . PC1 G 2 .   ? 143.619 146.259 128.339 1.00 91.74  ? 802 PC1 B O11 1 
HETATM 6551 C C1  . PC1 G 2 .   ? 144.230 146.735 129.519 1.00 80.17  ? 802 PC1 B C1  1 
HETATM 6552 C C2  . PC1 G 2 .   ? 143.209 146.679 130.632 1.00 75.76  ? 802 PC1 B C2  1 
HETATM 6553 O O21 . PC1 G 2 .   ? 143.802 146.860 131.919 1.00 72.93  ? 802 PC1 B O21 1 
HETATM 6554 C C21 . PC1 G 2 .   ? 143.035 147.266 132.926 1.00 65.67  ? 802 PC1 B C21 1 
HETATM 6555 O O22 . PC1 G 2 .   ? 142.317 148.227 132.868 1.00 64.97  ? 802 PC1 B O22 1 
HETATM 6556 C C22 . PC1 G 2 .   ? 143.182 146.372 134.121 1.00 61.25  ? 802 PC1 B C22 1 
HETATM 6557 C C23 . PC1 G 2 .   ? 142.063 146.511 135.139 1.00 57.98  ? 802 PC1 B C23 1 
HETATM 6558 C C24 . PC1 G 2 .   ? 142.299 147.664 136.105 1.00 54.86  ? 802 PC1 B C24 1 
HETATM 6559 C C25 . PC1 G 2 .   ? 141.281 147.722 137.232 1.00 48.59  ? 802 PC1 B C25 1 
HETATM 6560 C C26 . PC1 G 2 .   ? 141.252 146.446 138.057 1.00 47.38  ? 802 PC1 B C26 1 
HETATM 6561 C C27 . PC1 G 2 .   ? 140.482 146.594 139.361 1.00 55.11  ? 802 PC1 B C27 1 
HETATM 6562 C C28 . PC1 G 2 .   ? 141.357 147.027 140.531 1.00 57.72  ? 802 PC1 B C28 1 
HETATM 6563 C C29 . PC1 G 2 .   ? 140.649 147.920 141.544 1.00 59.74  ? 802 PC1 B C29 1 
HETATM 6564 C C2A . PC1 G 2 .   ? 140.237 149.267 140.961 1.00 63.25  ? 802 PC1 B C2A 1 
HETATM 6565 C C2B . PC1 G 2 .   ? 140.572 150.459 141.850 1.00 59.14  ? 802 PC1 B C2B 1 
HETATM 6566 C C2C . PC1 G 2 .   ? 139.596 150.646 143.005 1.00 56.47  ? 802 PC1 B C2C 1 
HETATM 6567 C C2D . PC1 G 2 .   ? 138.150 150.870 142.576 1.00 53.29  ? 802 PC1 B C2D 1 
HETATM 6568 C C2E . PC1 G 2 .   ? 137.212 151.153 143.744 1.00 49.83  ? 802 PC1 B C2E 1 
HETATM 6569 C C2F . PC1 G 2 .   ? 136.011 150.219 143.822 1.00 51.82  ? 802 PC1 B C2F 1 
HETATM 6570 C C2G . PC1 G 2 .   ? 136.316 148.896 144.513 1.00 55.69  ? 802 PC1 B C2G 1 
HETATM 6571 C C2H . PC1 G 2 .   ? 135.371 147.762 144.131 1.00 57.39  ? 802 PC1 B C2H 1 
HETATM 6572 C C2I . PC1 G 2 .   ? 133.956 147.944 144.657 1.00 55.47  ? 802 PC1 B C2I 1 
HETATM 6573 C C3  . PC1 G 2 .   ? 142.537 145.325 130.655 1.00 80.75  ? 802 PC1 B C3  1 
HETATM 6574 O O31 . PC1 G 2 .   ? 141.146 145.545 130.459 1.00 77.56  ? 802 PC1 B O31 1 
HETATM 6575 C C31 . PC1 G 2 .   ? 140.376 144.481 130.269 1.00 74.95  ? 802 PC1 B C31 1 
HETATM 6576 O O32 . PC1 G 2 .   ? 140.640 143.612 129.479 1.00 73.39  ? 802 PC1 B O32 1 
HETATM 6577 C C32 . PC1 G 2 .   ? 139.164 144.515 131.154 1.00 72.35  ? 802 PC1 B C32 1 
HETATM 6578 C C33 . PC1 G 2 .   ? 139.146 145.677 132.136 1.00 68.32  ? 802 PC1 B C33 1 
HETATM 6579 C C34 . PC1 G 2 .   ? 137.870 145.676 132.967 1.00 60.45  ? 802 PC1 B C34 1 
HETATM 6580 C C35 . PC1 G 2 .   ? 137.726 144.451 133.858 1.00 56.55  ? 802 PC1 B C35 1 
HETATM 6581 C C36 . PC1 G 2 .   ? 138.923 144.267 134.776 1.00 49.39  ? 802 PC1 B C36 1 
HETATM 6582 C C37 . PC1 G 2 .   ? 138.605 144.532 136.236 1.00 47.60  ? 802 PC1 B C37 1 
HETATM 6583 C C38 . PC1 G 2 .   ? 138.041 143.305 136.932 1.00 50.54  ? 802 PC1 B C38 1 
HETATM 6584 C C39 . PC1 G 2 .   ? 138.098 143.414 138.447 1.00 59.16  ? 802 PC1 B C39 1 
HETATM 6585 C C3A . PC1 G 2 .   ? 137.629 142.153 139.155 1.00 73.19  ? 802 PC1 B C3A 1 
HETATM 6586 C C3B . PC1 G 2 .   ? 137.260 142.405 140.608 1.00 73.79  ? 802 PC1 B C3B 1 
HETATM 6587 C C3C . PC1 G 2 .   ? 138.267 143.292 141.331 1.00 70.64  ? 802 PC1 B C3C 1 
HETATM 6588 C C3D . PC1 G 2 .   ? 138.416 142.974 142.813 1.00 84.19  ? 802 PC1 B C3D 1 
HETATM 6589 C C3E . PC1 G 2 .   ? 139.665 142.162 143.141 1.00 92.38  ? 802 PC1 B C3E 1 
HETATM 6590 C C3F . PC1 G 2 .   ? 139.573 140.687 142.763 1.00 89.38  ? 802 PC1 B C3F 1 
HETATM 6591 C C3G . PC1 G 2 .   ? 140.497 140.302 141.614 1.00 88.50  ? 802 PC1 B C3G 1 
HETATM 6592 C C3H . PC1 G 2 .   ? 140.540 138.803 141.344 1.00 88.53  ? 802 PC1 B C3H 1 
HETATM 6593 C C3I . PC1 G 2 .   ? 141.465 138.440 140.190 1.00 82.81  ? 802 PC1 B C3I 1 
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