data_9J3U
# 
_entry.id   9J3U 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9J3U         pdb_00009j3u 10.2210/pdb9j3u/pdb 
WWPDB D_1300050284 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'Structure model' 1 1 2025-05-07 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9J3U 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              khara@u-shizuoka-ken.ac.jp 
_pdbx_contact_author.name_first         Kodai 
_pdbx_contact_author.name_last          Hara 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1586-6312 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hara, K.'      1 ? 
'Kobayashi, T.' 2 ? 
'Ohishi, S.'    3 ? 
'Hashimoto, H.' 4 ? 
'Watanabe, K.'  5 ? 
'Miyoshi, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                8786 
_citation.page_last                 8795 
_citation.title                     
'3,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.5c00418 
_citation.pdbx_database_id_PubMed   40173106 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kobayashi, T.' 1 ? 
primary 'Oishi, S.'     2 ? 
primary 'Hara, K.'      3 ? 
primary 'Matsui, M.'    4 ? 
primary 'Mena, P.'      5 ? 
primary 'Hashimoto, H.' 6 ? 
primary 'Watanabe, K.'  7 ? 
primary 'Miyoshi, N.'   8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Tyrosine phenol-lyase' 52196.621 2   4.1.99.2 ? ? ? 
2 non-polymer syn 3,5-DIHYDROXYBENZOATE   154.120   2   ?        ? ? ? 
3 non-polymer syn 'POTASSIUM ION'         39.098    2   ?        ? ? ? 
4 water       nat water                   18.015    588 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        Beta-tyrosinase 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;MMYPAEPYRIKSVETVSMIPREERIKRMREAGYNTFLLNSKDVYVDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFFHL
ERTVQELFGFKHIVPTHQGRGAENLLSSLAIKPGQYVAGNMYFTTTRYHQEKNGATFIDIVRDEAHDAGLDVKFKGNIDI
KKLEKLIAEKGAENIAYICLAVTVNLAGGQPVSMANMREVRQLCDKHGIKVFYDATRCVENAYFIKEQEEGFEDVSIKDI
VHEMFSYADGCTMSGK(LLP)DCLVNIGGFLCMNDDDMFSAARELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQFEYIE
HRVKQVRYLGEKLKAAGVPIVEPVGGHAVFLDARRFCPHLTQDEFPAQSLAASIYMETGVRSMERGIISAGRNKETGDHH
RPKLETVRLTIPRRVYTYAHMDLVADGIIKLFKHKEDIKGLKFVYEPKQLRFFTARFDYVHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MMYPAEPYRIKSVETVSMIPREERIKRMREAGYNTFLLNSKDVYVDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFFHL
ERTVQELFGFKHIVPTHQGRGAENLLSSLAIKPGQYVAGNMYFTTTRYHQEKNGATFIDIVRDEAHDAGLDVKFKGNIDI
KKLEKLIAEKGAENIAYICLAVTVNLAGGQPVSMANMREVRQLCDKHGIKVFYDATRCVENAYFIKEQEEGFEDVSIKDI
VHEMFSYADGCTMSGKKDCLVNIGGFLCMNDDDMFSAARELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQFEYIEHRVK
QVRYLGEKLKAAGVPIVEPVGGHAVFLDARRFCPHLTQDEFPAQSLAASIYMETGVRSMERGIISAGRNKETGDHHRPKL
ETVRLTIPRRVYTYAHMDLVADGIIKLFKHKEDIKGLKFVYEPKQLRFFTARFDYVHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 3,5-DIHYDROXYBENZOATE 34D 
3 'POTASSIUM ION'       K   
4 water                 HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   MET n 
1 3   TYR n 
1 4   PRO n 
1 5   ALA n 
1 6   GLU n 
1 7   PRO n 
1 8   TYR n 
1 9   ARG n 
1 10  ILE n 
1 11  LYS n 
1 12  SER n 
1 13  VAL n 
1 14  GLU n 
1 15  THR n 
1 16  VAL n 
1 17  SER n 
1 18  MET n 
1 19  ILE n 
1 20  PRO n 
1 21  ARG n 
1 22  GLU n 
1 23  GLU n 
1 24  ARG n 
1 25  ILE n 
1 26  LYS n 
1 27  ARG n 
1 28  MET n 
1 29  ARG n 
1 30  GLU n 
1 31  ALA n 
1 32  GLY n 
1 33  TYR n 
1 34  ASN n 
1 35  THR n 
1 36  PHE n 
1 37  LEU n 
1 38  LEU n 
1 39  ASN n 
1 40  SER n 
1 41  LYS n 
1 42  ASP n 
1 43  VAL n 
1 44  TYR n 
1 45  VAL n 
1 46  ASP n 
1 47  LEU n 
1 48  LEU n 
1 49  THR n 
1 50  ASP n 
1 51  SER n 
1 52  GLY n 
1 53  THR n 
1 54  ASN n 
1 55  ALA n 
1 56  MET n 
1 57  SER n 
1 58  ASP n 
1 59  LYS n 
1 60  GLN n 
1 61  TRP n 
1 62  ALA n 
1 63  GLY n 
1 64  MET n 
1 65  MET n 
1 66  MET n 
1 67  GLY n 
1 68  ASP n 
1 69  GLU n 
1 70  ALA n 
1 71  TYR n 
1 72  ALA n 
1 73  GLY n 
1 74  SER n 
1 75  GLU n 
1 76  ASN n 
1 77  PHE n 
1 78  PHE n 
1 79  HIS n 
1 80  LEU n 
1 81  GLU n 
1 82  ARG n 
1 83  THR n 
1 84  VAL n 
1 85  GLN n 
1 86  GLU n 
1 87  LEU n 
1 88  PHE n 
1 89  GLY n 
1 90  PHE n 
1 91  LYS n 
1 92  HIS n 
1 93  ILE n 
1 94  VAL n 
1 95  PRO n 
1 96  THR n 
1 97  HIS n 
1 98  GLN n 
1 99  GLY n 
1 100 ARG n 
1 101 GLY n 
1 102 ALA n 
1 103 GLU n 
1 104 ASN n 
1 105 LEU n 
1 106 LEU n 
1 107 SER n 
1 108 SER n 
1 109 LEU n 
1 110 ALA n 
1 111 ILE n 
1 112 LYS n 
1 113 PRO n 
1 114 GLY n 
1 115 GLN n 
1 116 TYR n 
1 117 VAL n 
1 118 ALA n 
1 119 GLY n 
1 120 ASN n 
1 121 MET n 
1 122 TYR n 
1 123 PHE n 
1 124 THR n 
1 125 THR n 
1 126 THR n 
1 127 ARG n 
1 128 TYR n 
1 129 HIS n 
1 130 GLN n 
1 131 GLU n 
1 132 LYS n 
1 133 ASN n 
1 134 GLY n 
1 135 ALA n 
1 136 THR n 
1 137 PHE n 
1 138 ILE n 
1 139 ASP n 
1 140 ILE n 
1 141 VAL n 
1 142 ARG n 
1 143 ASP n 
1 144 GLU n 
1 145 ALA n 
1 146 HIS n 
1 147 ASP n 
1 148 ALA n 
1 149 GLY n 
1 150 LEU n 
1 151 ASP n 
1 152 VAL n 
1 153 LYS n 
1 154 PHE n 
1 155 LYS n 
1 156 GLY n 
1 157 ASN n 
1 158 ILE n 
1 159 ASP n 
1 160 ILE n 
1 161 LYS n 
1 162 LYS n 
1 163 LEU n 
1 164 GLU n 
1 165 LYS n 
1 166 LEU n 
1 167 ILE n 
1 168 ALA n 
1 169 GLU n 
1 170 LYS n 
1 171 GLY n 
1 172 ALA n 
1 173 GLU n 
1 174 ASN n 
1 175 ILE n 
1 176 ALA n 
1 177 TYR n 
1 178 ILE n 
1 179 CYS n 
1 180 LEU n 
1 181 ALA n 
1 182 VAL n 
1 183 THR n 
1 184 VAL n 
1 185 ASN n 
1 186 LEU n 
1 187 ALA n 
1 188 GLY n 
1 189 GLY n 
1 190 GLN n 
1 191 PRO n 
1 192 VAL n 
1 193 SER n 
1 194 MET n 
1 195 ALA n 
1 196 ASN n 
1 197 MET n 
1 198 ARG n 
1 199 GLU n 
1 200 VAL n 
1 201 ARG n 
1 202 GLN n 
1 203 LEU n 
1 204 CYS n 
1 205 ASP n 
1 206 LYS n 
1 207 HIS n 
1 208 GLY n 
1 209 ILE n 
1 210 LYS n 
1 211 VAL n 
1 212 PHE n 
1 213 TYR n 
1 214 ASP n 
1 215 ALA n 
1 216 THR n 
1 217 ARG n 
1 218 CYS n 
1 219 VAL n 
1 220 GLU n 
1 221 ASN n 
1 222 ALA n 
1 223 TYR n 
1 224 PHE n 
1 225 ILE n 
1 226 LYS n 
1 227 GLU n 
1 228 GLN n 
1 229 GLU n 
1 230 GLU n 
1 231 GLY n 
1 232 PHE n 
1 233 GLU n 
1 234 ASP n 
1 235 VAL n 
1 236 SER n 
1 237 ILE n 
1 238 LYS n 
1 239 ASP n 
1 240 ILE n 
1 241 VAL n 
1 242 HIS n 
1 243 GLU n 
1 244 MET n 
1 245 PHE n 
1 246 SER n 
1 247 TYR n 
1 248 ALA n 
1 249 ASP n 
1 250 GLY n 
1 251 CYS n 
1 252 THR n 
1 253 MET n 
1 254 SER n 
1 255 GLY n 
1 256 LYS n 
1 257 LLP n 
1 258 ASP n 
1 259 CYS n 
1 260 LEU n 
1 261 VAL n 
1 262 ASN n 
1 263 ILE n 
1 264 GLY n 
1 265 GLY n 
1 266 PHE n 
1 267 LEU n 
1 268 CYS n 
1 269 MET n 
1 270 ASN n 
1 271 ASP n 
1 272 ASP n 
1 273 ASP n 
1 274 MET n 
1 275 PHE n 
1 276 SER n 
1 277 ALA n 
1 278 ALA n 
1 279 ARG n 
1 280 GLU n 
1 281 LEU n 
1 282 VAL n 
1 283 VAL n 
1 284 VAL n 
1 285 TYR n 
1 286 GLU n 
1 287 GLY n 
1 288 MET n 
1 289 PRO n 
1 290 SER n 
1 291 TYR n 
1 292 GLY n 
1 293 GLY n 
1 294 LEU n 
1 295 ALA n 
1 296 GLY n 
1 297 ARG n 
1 298 ASP n 
1 299 MET n 
1 300 GLU n 
1 301 ALA n 
1 302 MET n 
1 303 ALA n 
1 304 ILE n 
1 305 GLY n 
1 306 LEU n 
1 307 ARG n 
1 308 GLU n 
1 309 ALA n 
1 310 MET n 
1 311 GLN n 
1 312 PHE n 
1 313 GLU n 
1 314 TYR n 
1 315 ILE n 
1 316 GLU n 
1 317 HIS n 
1 318 ARG n 
1 319 VAL n 
1 320 LYS n 
1 321 GLN n 
1 322 VAL n 
1 323 ARG n 
1 324 TYR n 
1 325 LEU n 
1 326 GLY n 
1 327 GLU n 
1 328 LYS n 
1 329 LEU n 
1 330 LYS n 
1 331 ALA n 
1 332 ALA n 
1 333 GLY n 
1 334 VAL n 
1 335 PRO n 
1 336 ILE n 
1 337 VAL n 
1 338 GLU n 
1 339 PRO n 
1 340 VAL n 
1 341 GLY n 
1 342 GLY n 
1 343 HIS n 
1 344 ALA n 
1 345 VAL n 
1 346 PHE n 
1 347 LEU n 
1 348 ASP n 
1 349 ALA n 
1 350 ARG n 
1 351 ARG n 
1 352 PHE n 
1 353 CYS n 
1 354 PRO n 
1 355 HIS n 
1 356 LEU n 
1 357 THR n 
1 358 GLN n 
1 359 ASP n 
1 360 GLU n 
1 361 PHE n 
1 362 PRO n 
1 363 ALA n 
1 364 GLN n 
1 365 SER n 
1 366 LEU n 
1 367 ALA n 
1 368 ALA n 
1 369 SER n 
1 370 ILE n 
1 371 TYR n 
1 372 MET n 
1 373 GLU n 
1 374 THR n 
1 375 GLY n 
1 376 VAL n 
1 377 ARG n 
1 378 SER n 
1 379 MET n 
1 380 GLU n 
1 381 ARG n 
1 382 GLY n 
1 383 ILE n 
1 384 ILE n 
1 385 SER n 
1 386 ALA n 
1 387 GLY n 
1 388 ARG n 
1 389 ASN n 
1 390 LYS n 
1 391 GLU n 
1 392 THR n 
1 393 GLY n 
1 394 ASP n 
1 395 HIS n 
1 396 HIS n 
1 397 ARG n 
1 398 PRO n 
1 399 LYS n 
1 400 LEU n 
1 401 GLU n 
1 402 THR n 
1 403 VAL n 
1 404 ARG n 
1 405 LEU n 
1 406 THR n 
1 407 ILE n 
1 408 PRO n 
1 409 ARG n 
1 410 ARG n 
1 411 VAL n 
1 412 TYR n 
1 413 THR n 
1 414 TYR n 
1 415 ALA n 
1 416 HIS n 
1 417 MET n 
1 418 ASP n 
1 419 LEU n 
1 420 VAL n 
1 421 ALA n 
1 422 ASP n 
1 423 GLY n 
1 424 ILE n 
1 425 ILE n 
1 426 LYS n 
1 427 LEU n 
1 428 PHE n 
1 429 LYS n 
1 430 HIS n 
1 431 LYS n 
1 432 GLU n 
1 433 ASP n 
1 434 ILE n 
1 435 LYS n 
1 436 GLY n 
1 437 LEU n 
1 438 LYS n 
1 439 PHE n 
1 440 VAL n 
1 441 TYR n 
1 442 GLU n 
1 443 PRO n 
1 444 LYS n 
1 445 GLN n 
1 446 LEU n 
1 447 ARG n 
1 448 PHE n 
1 449 PHE n 
1 450 THR n 
1 451 ALA n 
1 452 ARG n 
1 453 PHE n 
1 454 ASP n 
1 455 TYR n 
1 456 VAL n 
1 457 HIS n 
1 458 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   458 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'tpl, MU9_2951' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Morganella morganii subsp. morganii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     180434 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
34D non-polymer         . 3,5-DIHYDROXYBENZOATE                                                                                   
?                                      'C7 H6 O4'        154.120 
ALA 'L-peptide linking' y ALANINE                                                                                                 
?                                      'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                                                                                
?                                      'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                              
?                                      'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                         
?                                      'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                                
?                                      'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                               
?                                      'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                         
?                                      'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                                                                                 
?                                      'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                               
?                                      'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                                                                                   
?                                      'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                                              
?                                      'C6 H13 N O2'     131.173 
K   non-polymer         . 'POTASSIUM ION'                                                                                         
?                                      'K 1'             39.098  
LEU 'L-peptide linking' y LEUCINE                                                                                                 
?                                      'C6 H13 N O2'     131.173 
LLP 'L-peptide linking' n '(2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid' 
"N'-PYRIDOXYL-LYSINE-5'-MONOPHOSPHATE" 'C14 H22 N3 O7 P' 375.314 
LYS 'L-peptide linking' y LYSINE                                                                                                  
?                                      'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                                                                              
?                                      'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                           
?                                      'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                                                                                 
?                                      'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                                                                                                  
?                                      'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                                                                                               
?                                      'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                              
?                                      'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                                
?                                      'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                                                                                  
?                                      'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   MET 2   2   2   MET MET A . n 
A 1 3   TYR 3   3   3   TYR TYR A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   ALA 5   5   5   ALA ALA A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   PRO 7   7   7   PRO PRO A . n 
A 1 8   TYR 8   8   8   TYR TYR A . n 
A 1 9   ARG 9   9   9   ARG ARG A . n 
A 1 10  ILE 10  10  10  ILE ILE A . n 
A 1 11  LYS 11  11  11  LYS LYS A . n 
A 1 12  SER 12  12  12  SER SER A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  THR 15  15  15  THR THR A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  MET 18  18  18  MET MET A . n 
A 1 19  ILE 19  19  19  ILE ILE A . n 
A 1 20  PRO 20  20  20  PRO PRO A . n 
A 1 21  ARG 21  21  21  ARG ARG A . n 
A 1 22  GLU 22  22  22  GLU GLU A . n 
A 1 23  GLU 23  23  23  GLU GLU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  ILE 25  25  25  ILE ILE A . n 
A 1 26  LYS 26  26  26  LYS LYS A . n 
A 1 27  ARG 27  27  27  ARG ARG A . n 
A 1 28  MET 28  28  28  MET MET A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  ALA 31  31  31  ALA ALA A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  TYR 33  33  33  TYR TYR A . n 
A 1 34  ASN 34  34  34  ASN ASN A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LYS 41  41  41  LYS LYS A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  TYR 44  44  44  TYR TYR A . n 
A 1 45  VAL 45  45  45  VAL VAL A . n 
A 1 46  ASP 46  46  46  ASP ASP A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  ASP 50  50  50  ASP ASP A . n 
A 1 51  SER 51  51  51  SER SER A . n 
A 1 52  GLY 52  52  52  GLY GLY A . n 
A 1 53  THR 53  53  53  THR THR A . n 
A 1 54  ASN 54  54  54  ASN ASN A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  MET 56  56  56  MET MET A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  TRP 61  61  61  TRP TRP A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  MET 64  64  64  MET MET A . n 
A 1 65  MET 65  65  65  MET MET A . n 
A 1 66  MET 66  66  66  MET MET A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  ASP 68  68  68  ASP ASP A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  TYR 71  71  71  TYR TYR A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  GLY 73  73  73  GLY GLY A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  ASN 76  76  76  ASN ASN A . n 
A 1 77  PHE 77  77  77  PHE PHE A . n 
A 1 78  PHE 78  78  78  PHE PHE A . n 
A 1 79  HIS 79  79  79  HIS HIS A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  GLU 81  81  81  GLU GLU A . n 
A 1 82  ARG 82  82  82  ARG ARG A . n 
A 1 83  THR 83  83  83  THR THR A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  GLN 85  85  85  GLN GLN A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  PHE 90  90  90  PHE PHE A . n 
A 1 91  LYS 91  91  91  LYS LYS A . n 
A 1 92  HIS 92  92  92  HIS HIS A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  PRO 95  95  95  PRO PRO A . n 
A 1 96  THR 96  96  96  THR THR A . n 
A 1 97  HIS 97  97  97  HIS HIS A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 ASN 104 104 104 ASN ASN A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 ILE 111 111 111 ILE ILE A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 GLN 115 115 115 GLN GLN A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 VAL 117 117 117 VAL VAL A . n 
A 1 118 ALA 118 118 118 ALA ALA A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 MET 121 121 121 MET MET A . n 
A 1 122 TYR 122 122 122 TYR TYR A . n 
A 1 123 PHE 123 123 123 PHE PHE A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 THR 126 126 126 THR THR A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 TYR 128 128 128 TYR TYR A . n 
A 1 129 HIS 129 129 129 HIS HIS A . n 
A 1 130 GLN 130 130 130 GLN GLN A . n 
A 1 131 GLU 131 131 131 GLU GLU A . n 
A 1 132 LYS 132 132 132 LYS LYS A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 PHE 137 137 137 PHE PHE A . n 
A 1 138 ILE 138 138 138 ILE ILE A . n 
A 1 139 ASP 139 139 139 ASP ASP A . n 
A 1 140 ILE 140 140 140 ILE ILE A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 ARG 142 142 142 ARG ARG A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 HIS 146 146 146 HIS HIS A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 ASP 151 151 151 ASP ASP A . n 
A 1 152 VAL 152 152 152 VAL VAL A . n 
A 1 153 LYS 153 153 153 LYS LYS A . n 
A 1 154 PHE 154 154 154 PHE PHE A . n 
A 1 155 LYS 155 155 155 LYS LYS A . n 
A 1 156 GLY 156 156 156 GLY GLY A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 ILE 160 160 160 ILE ILE A . n 
A 1 161 LYS 161 161 161 LYS LYS A . n 
A 1 162 LYS 162 162 162 LYS LYS A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 LYS 165 165 165 LYS LYS A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 ILE 167 167 167 ILE ILE A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 LYS 170 170 170 LYS LYS A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ASN 174 174 174 ASN ASN A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 TYR 177 177 177 TYR TYR A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 CYS 179 179 179 CYS CYS A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 ASN 185 185 185 ASN ASN A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 GLY 189 189 189 GLY GLY A . n 
A 1 190 GLN 190 190 190 GLN GLN A . n 
A 1 191 PRO 191 191 191 PRO PRO A . n 
A 1 192 VAL 192 192 192 VAL VAL A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 ASN 196 196 196 ASN ASN A . n 
A 1 197 MET 197 197 197 MET MET A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 GLU 199 199 199 GLU GLU A . n 
A 1 200 VAL 200 200 200 VAL VAL A . n 
A 1 201 ARG 201 201 201 ARG ARG A . n 
A 1 202 GLN 202 202 202 GLN GLN A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 CYS 204 204 204 CYS CYS A . n 
A 1 205 ASP 205 205 205 ASP ASP A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 HIS 207 207 207 HIS HIS A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 VAL 211 211 211 VAL VAL A . n 
A 1 212 PHE 212 212 212 PHE PHE A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 ASP 214 214 214 ASP ASP A . n 
A 1 215 ALA 215 215 215 ALA ALA A . n 
A 1 216 THR 216 216 216 THR THR A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 CYS 218 218 218 CYS CYS A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 GLU 220 220 220 GLU GLU A . n 
A 1 221 ASN 221 221 221 ASN ASN A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 TYR 223 223 223 TYR TYR A . n 
A 1 224 PHE 224 224 224 PHE PHE A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 LYS 226 226 226 LYS LYS A . n 
A 1 227 GLU 227 227 227 GLU GLU A . n 
A 1 228 GLN 228 228 228 GLN GLN A . n 
A 1 229 GLU 229 229 229 GLU GLU A . n 
A 1 230 GLU 230 230 230 GLU GLU A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 GLU 233 233 233 GLU GLU A . n 
A 1 234 ASP 234 234 234 ASP ASP A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 ASP 239 239 239 ASP ASP A . n 
A 1 240 ILE 240 240 240 ILE ILE A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 HIS 242 242 242 HIS HIS A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 MET 244 244 244 MET MET A . n 
A 1 245 PHE 245 245 245 PHE PHE A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 ASP 249 249 249 ASP ASP A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 CYS 251 251 251 CYS CYS A . n 
A 1 252 THR 252 252 252 THR THR A . n 
A 1 253 MET 253 253 253 MET MET A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 GLY 255 255 255 GLY GLY A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 LLP 257 257 257 LLP LLP A . n 
A 1 258 ASP 258 258 258 ASP ASP A . n 
A 1 259 CYS 259 259 259 CYS CYS A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 ASN 262 262 262 ASN ASN A . n 
A 1 263 ILE 263 263 263 ILE ILE A . n 
A 1 264 GLY 264 264 264 GLY GLY A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 PHE 266 266 266 PHE PHE A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 CYS 268 268 268 CYS CYS A . n 
A 1 269 MET 269 269 269 MET MET A . n 
A 1 270 ASN 270 270 270 ASN ASN A . n 
A 1 271 ASP 271 271 271 ASP ASP A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 MET 274 274 274 MET MET A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 ARG 279 279 279 ARG ARG A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 VAL 283 283 283 VAL VAL A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 TYR 285 285 285 TYR TYR A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 GLY 287 287 287 GLY GLY A . n 
A 1 288 MET 288 288 288 MET MET A . n 
A 1 289 PRO 289 289 289 PRO PRO A . n 
A 1 290 SER 290 290 290 SER SER A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 GLY 293 293 293 GLY GLY A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 ARG 297 297 297 ARG ARG A . n 
A 1 298 ASP 298 298 298 ASP ASP A . n 
A 1 299 MET 299 299 299 MET MET A . n 
A 1 300 GLU 300 300 300 GLU GLU A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 MET 302 302 302 MET MET A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 ILE 304 304 304 ILE ILE A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 LEU 306 306 306 LEU LEU A . n 
A 1 307 ARG 307 307 307 ARG ARG A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 MET 310 310 310 MET MET A . n 
A 1 311 GLN 311 311 311 GLN GLN A . n 
A 1 312 PHE 312 312 312 PHE PHE A . n 
A 1 313 GLU 313 313 313 GLU GLU A . n 
A 1 314 TYR 314 314 314 TYR TYR A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 GLU 316 316 316 GLU GLU A . n 
A 1 317 HIS 317 317 317 HIS HIS A . n 
A 1 318 ARG 318 318 318 ARG ARG A . n 
A 1 319 VAL 319 319 319 VAL VAL A . n 
A 1 320 LYS 320 320 320 LYS LYS A . n 
A 1 321 GLN 321 321 321 GLN GLN A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 TYR 324 324 324 TYR TYR A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 LYS 328 328 328 LYS LYS A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 LYS 330 330 330 LYS LYS A . n 
A 1 331 ALA 331 331 331 ALA ALA A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 GLY 333 333 333 GLY GLY A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 PRO 335 335 335 PRO PRO A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 GLU 338 338 338 GLU GLU A . n 
A 1 339 PRO 339 339 339 PRO PRO A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 GLY 341 341 341 GLY GLY A . n 
A 1 342 GLY 342 342 342 GLY GLY A . n 
A 1 343 HIS 343 343 343 HIS HIS A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 VAL 345 345 345 VAL VAL A . n 
A 1 346 PHE 346 346 346 PHE PHE A . n 
A 1 347 LEU 347 347 347 LEU LEU A . n 
A 1 348 ASP 348 348 348 ASP ASP A . n 
A 1 349 ALA 349 349 349 ALA ALA A . n 
A 1 350 ARG 350 350 350 ARG ARG A . n 
A 1 351 ARG 351 351 351 ARG ARG A . n 
A 1 352 PHE 352 352 352 PHE PHE A . n 
A 1 353 CYS 353 353 353 CYS CYS A . n 
A 1 354 PRO 354 354 354 PRO PRO A . n 
A 1 355 HIS 355 355 355 HIS HIS A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 THR 357 357 357 THR THR A . n 
A 1 358 GLN 358 358 358 GLN GLN A . n 
A 1 359 ASP 359 359 359 ASP ASP A . n 
A 1 360 GLU 360 360 360 GLU GLU A . n 
A 1 361 PHE 361 361 361 PHE PHE A . n 
A 1 362 PRO 362 362 362 PRO PRO A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 GLN 364 364 364 GLN GLN A . n 
A 1 365 SER 365 365 365 SER SER A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 SER 369 369 369 SER SER A . n 
A 1 370 ILE 370 370 370 ILE ILE A . n 
A 1 371 TYR 371 371 371 TYR TYR A . n 
A 1 372 MET 372 372 372 MET MET A . n 
A 1 373 GLU 373 373 373 GLU GLU A . n 
A 1 374 THR 374 374 374 THR THR A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 VAL 376 376 376 VAL VAL A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 SER 378 378 378 SER SER A . n 
A 1 379 MET 379 379 379 MET MET A . n 
A 1 380 GLU 380 380 380 GLU GLU A . n 
A 1 381 ARG 381 381 381 ARG ARG A . n 
A 1 382 GLY 382 382 382 GLY GLY A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 ILE 384 384 384 ILE ILE A . n 
A 1 385 SER 385 385 385 SER SER A . n 
A 1 386 ALA 386 386 386 ALA ALA A . n 
A 1 387 GLY 387 387 387 GLY GLY A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 ASN 389 389 389 ASN ASN A . n 
A 1 390 LYS 390 390 390 LYS LYS A . n 
A 1 391 GLU 391 391 391 GLU GLU A . n 
A 1 392 THR 392 392 392 THR THR A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 ASP 394 394 394 ASP ASP A . n 
A 1 395 HIS 395 395 395 HIS HIS A . n 
A 1 396 HIS 396 396 396 HIS HIS A . n 
A 1 397 ARG 397 397 397 ARG ARG A . n 
A 1 398 PRO 398 398 398 PRO PRO A . n 
A 1 399 LYS 399 399 399 LYS LYS A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 GLU 401 401 401 GLU GLU A . n 
A 1 402 THR 402 402 402 THR THR A . n 
A 1 403 VAL 403 403 403 VAL VAL A . n 
A 1 404 ARG 404 404 404 ARG ARG A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 THR 406 406 406 THR THR A . n 
A 1 407 ILE 407 407 407 ILE ILE A . n 
A 1 408 PRO 408 408 408 PRO PRO A . n 
A 1 409 ARG 409 409 409 ARG ARG A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 VAL 411 411 411 VAL VAL A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 THR 413 413 413 THR THR A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 HIS 416 416 416 HIS HIS A . n 
A 1 417 MET 417 417 417 MET MET A . n 
A 1 418 ASP 418 418 418 ASP ASP A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 VAL 420 420 420 VAL VAL A . n 
A 1 421 ALA 421 421 421 ALA ALA A . n 
A 1 422 ASP 422 422 422 ASP ASP A . n 
A 1 423 GLY 423 423 423 GLY GLY A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 LYS 426 426 426 LYS LYS A . n 
A 1 427 LEU 427 427 427 LEU LEU A . n 
A 1 428 PHE 428 428 428 PHE PHE A . n 
A 1 429 LYS 429 429 429 LYS LYS A . n 
A 1 430 HIS 430 430 430 HIS HIS A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 GLU 432 432 432 GLU GLU A . n 
A 1 433 ASP 433 433 433 ASP ASP A . n 
A 1 434 ILE 434 434 434 ILE ILE A . n 
A 1 435 LYS 435 435 435 LYS LYS A . n 
A 1 436 GLY 436 436 436 GLY GLY A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 LYS 438 438 438 LYS LYS A . n 
A 1 439 PHE 439 439 439 PHE PHE A . n 
A 1 440 VAL 440 440 440 VAL VAL A . n 
A 1 441 TYR 441 441 441 TYR TYR A . n 
A 1 442 GLU 442 442 442 GLU GLU A . n 
A 1 443 PRO 443 443 443 PRO PRO A . n 
A 1 444 LYS 444 444 444 LYS LYS A . n 
A 1 445 GLN 445 445 445 GLN GLN A . n 
A 1 446 LEU 446 446 446 LEU LEU A . n 
A 1 447 ARG 447 447 447 ARG ARG A . n 
A 1 448 PHE 448 448 448 PHE PHE A . n 
A 1 449 PHE 449 449 449 PHE PHE A . n 
A 1 450 THR 450 450 450 THR THR A . n 
A 1 451 ALA 451 451 451 ALA ALA A . n 
A 1 452 ARG 452 452 452 ARG ARG A . n 
A 1 453 PHE 453 453 453 PHE PHE A . n 
A 1 454 ASP 454 454 454 ASP ASP A . n 
A 1 455 TYR 455 455 455 TYR TYR A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 HIS 457 457 457 HIS HIS A . n 
A 1 458 HIS 458 458 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   MET 2   2   2   MET MET B . n 
B 1 3   TYR 3   3   3   TYR TYR B . n 
B 1 4   PRO 4   4   4   PRO PRO B . n 
B 1 5   ALA 5   5   5   ALA ALA B . n 
B 1 6   GLU 6   6   6   GLU GLU B . n 
B 1 7   PRO 7   7   7   PRO PRO B . n 
B 1 8   TYR 8   8   8   TYR TYR B . n 
B 1 9   ARG 9   9   9   ARG ARG B . n 
B 1 10  ILE 10  10  10  ILE ILE B . n 
B 1 11  LYS 11  11  11  LYS LYS B . n 
B 1 12  SER 12  12  12  SER SER B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  GLU 14  14  14  GLU GLU B . n 
B 1 15  THR 15  15  15  THR THR B . n 
B 1 16  VAL 16  16  16  VAL VAL B . n 
B 1 17  SER 17  17  17  SER SER B . n 
B 1 18  MET 18  18  18  MET MET B . n 
B 1 19  ILE 19  19  19  ILE ILE B . n 
B 1 20  PRO 20  20  20  PRO PRO B . n 
B 1 21  ARG 21  21  21  ARG ARG B . n 
B 1 22  GLU 22  22  22  GLU GLU B . n 
B 1 23  GLU 23  23  23  GLU GLU B . n 
B 1 24  ARG 24  24  24  ARG ARG B . n 
B 1 25  ILE 25  25  25  ILE ILE B . n 
B 1 26  LYS 26  26  26  LYS LYS B . n 
B 1 27  ARG 27  27  27  ARG ARG B . n 
B 1 28  MET 28  28  28  MET MET B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  ALA 31  31  31  ALA ALA B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  TYR 33  33  33  TYR TYR B . n 
B 1 34  ASN 34  34  34  ASN ASN B . n 
B 1 35  THR 35  35  35  THR THR B . n 
B 1 36  PHE 36  36  36  PHE PHE B . n 
B 1 37  LEU 37  37  37  LEU LEU B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LYS 41  41  41  LYS LYS B . n 
B 1 42  ASP 42  42  42  ASP ASP B . n 
B 1 43  VAL 43  43  43  VAL VAL B . n 
B 1 44  TYR 44  44  44  TYR TYR B . n 
B 1 45  VAL 45  45  45  VAL VAL B . n 
B 1 46  ASP 46  46  46  ASP ASP B . n 
B 1 47  LEU 47  47  47  LEU LEU B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  ASP 50  50  50  ASP ASP B . n 
B 1 51  SER 51  51  51  SER SER B . n 
B 1 52  GLY 52  52  52  GLY GLY B . n 
B 1 53  THR 53  53  53  THR THR B . n 
B 1 54  ASN 54  54  54  ASN ASN B . n 
B 1 55  ALA 55  55  55  ALA ALA B . n 
B 1 56  MET 56  56  56  MET MET B . n 
B 1 57  SER 57  57  57  SER SER B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  LYS 59  59  59  LYS LYS B . n 
B 1 60  GLN 60  60  60  GLN GLN B . n 
B 1 61  TRP 61  61  61  TRP TRP B . n 
B 1 62  ALA 62  62  62  ALA ALA B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  MET 64  64  64  MET MET B . n 
B 1 65  MET 65  65  65  MET MET B . n 
B 1 66  MET 66  66  66  MET MET B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  ASP 68  68  68  ASP ASP B . n 
B 1 69  GLU 69  69  69  GLU GLU B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  TYR 71  71  71  TYR TYR B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  GLY 73  73  73  GLY GLY B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  GLU 75  75  75  GLU GLU B . n 
B 1 76  ASN 76  76  76  ASN ASN B . n 
B 1 77  PHE 77  77  77  PHE PHE B . n 
B 1 78  PHE 78  78  78  PHE PHE B . n 
B 1 79  HIS 79  79  79  HIS HIS B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  GLU 81  81  81  GLU GLU B . n 
B 1 82  ARG 82  82  82  ARG ARG B . n 
B 1 83  THR 83  83  83  THR THR B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  GLN 85  85  85  GLN GLN B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  LEU 87  87  87  LEU LEU B . n 
B 1 88  PHE 88  88  88  PHE PHE B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  PHE 90  90  90  PHE PHE B . n 
B 1 91  LYS 91  91  91  LYS LYS B . n 
B 1 92  HIS 92  92  92  HIS HIS B . n 
B 1 93  ILE 93  93  93  ILE ILE B . n 
B 1 94  VAL 94  94  94  VAL VAL B . n 
B 1 95  PRO 95  95  95  PRO PRO B . n 
B 1 96  THR 96  96  96  THR THR B . n 
B 1 97  HIS 97  97  97  HIS HIS B . n 
B 1 98  GLN 98  98  98  GLN GLN B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 ARG 100 100 100 ARG ARG B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 ALA 102 102 102 ALA ALA B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 ASN 104 104 104 ASN ASN B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 SER 107 107 107 SER SER B . n 
B 1 108 SER 108 108 108 SER SER B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 ILE 111 111 111 ILE ILE B . n 
B 1 112 LYS 112 112 112 LYS LYS B . n 
B 1 113 PRO 113 113 113 PRO PRO B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 GLN 115 115 115 GLN GLN B . n 
B 1 116 TYR 116 116 116 TYR TYR B . n 
B 1 117 VAL 117 117 117 VAL VAL B . n 
B 1 118 ALA 118 118 118 ALA ALA B . n 
B 1 119 GLY 119 119 119 GLY GLY B . n 
B 1 120 ASN 120 120 120 ASN ASN B . n 
B 1 121 MET 121 121 121 MET MET B . n 
B 1 122 TYR 122 122 122 TYR TYR B . n 
B 1 123 PHE 123 123 123 PHE PHE B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 THR 125 125 125 THR THR B . n 
B 1 126 THR 126 126 126 THR THR B . n 
B 1 127 ARG 127 127 127 ARG ARG B . n 
B 1 128 TYR 128 128 128 TYR TYR B . n 
B 1 129 HIS 129 129 129 HIS HIS B . n 
B 1 130 GLN 130 130 130 GLN GLN B . n 
B 1 131 GLU 131 131 131 GLU GLU B . n 
B 1 132 LYS 132 132 132 LYS LYS B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 ALA 135 135 135 ALA ALA B . n 
B 1 136 THR 136 136 136 THR THR B . n 
B 1 137 PHE 137 137 137 PHE PHE B . n 
B 1 138 ILE 138 138 138 ILE ILE B . n 
B 1 139 ASP 139 139 139 ASP ASP B . n 
B 1 140 ILE 140 140 140 ILE ILE B . n 
B 1 141 VAL 141 141 141 VAL VAL B . n 
B 1 142 ARG 142 142 142 ARG ARG B . n 
B 1 143 ASP 143 143 143 ASP ASP B . n 
B 1 144 GLU 144 144 144 GLU GLU B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 HIS 146 146 146 HIS HIS B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 LEU 150 150 150 LEU LEU B . n 
B 1 151 ASP 151 151 151 ASP ASP B . n 
B 1 152 VAL 152 152 152 VAL VAL B . n 
B 1 153 LYS 153 153 153 LYS LYS B . n 
B 1 154 PHE 154 154 154 PHE PHE B . n 
B 1 155 LYS 155 155 155 LYS LYS B . n 
B 1 156 GLY 156 156 156 GLY GLY B . n 
B 1 157 ASN 157 157 157 ASN ASN B . n 
B 1 158 ILE 158 158 158 ILE ILE B . n 
B 1 159 ASP 159 159 159 ASP ASP B . n 
B 1 160 ILE 160 160 160 ILE ILE B . n 
B 1 161 LYS 161 161 161 LYS LYS B . n 
B 1 162 LYS 162 162 162 LYS LYS B . n 
B 1 163 LEU 163 163 163 LEU LEU B . n 
B 1 164 GLU 164 164 164 GLU GLU B . n 
B 1 165 LYS 165 165 165 LYS LYS B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 ILE 167 167 167 ILE ILE B . n 
B 1 168 ALA 168 168 168 ALA ALA B . n 
B 1 169 GLU 169 169 169 GLU GLU B . n 
B 1 170 LYS 170 170 170 LYS LYS B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 ALA 172 172 172 ALA ALA B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 ASN 174 174 174 ASN ASN B . n 
B 1 175 ILE 175 175 175 ILE ILE B . n 
B 1 176 ALA 176 176 176 ALA ALA B . n 
B 1 177 TYR 177 177 177 TYR TYR B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 CYS 179 179 179 CYS CYS B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 THR 183 183 183 THR THR B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 ASN 185 185 185 ASN ASN B . n 
B 1 186 LEU 186 186 186 LEU LEU B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 GLY 188 188 188 GLY GLY B . n 
B 1 189 GLY 189 189 189 GLY GLY B . n 
B 1 190 GLN 190 190 190 GLN GLN B . n 
B 1 191 PRO 191 191 191 PRO PRO B . n 
B 1 192 VAL 192 192 192 VAL VAL B . n 
B 1 193 SER 193 193 193 SER SER B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 ALA 195 195 195 ALA ALA B . n 
B 1 196 ASN 196 196 196 ASN ASN B . n 
B 1 197 MET 197 197 197 MET MET B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 GLU 199 199 199 GLU GLU B . n 
B 1 200 VAL 200 200 200 VAL VAL B . n 
B 1 201 ARG 201 201 201 ARG ARG B . n 
B 1 202 GLN 202 202 202 GLN GLN B . n 
B 1 203 LEU 203 203 203 LEU LEU B . n 
B 1 204 CYS 204 204 204 CYS CYS B . n 
B 1 205 ASP 205 205 205 ASP ASP B . n 
B 1 206 LYS 206 206 206 LYS LYS B . n 
B 1 207 HIS 207 207 207 HIS HIS B . n 
B 1 208 GLY 208 208 208 GLY GLY B . n 
B 1 209 ILE 209 209 209 ILE ILE B . n 
B 1 210 LYS 210 210 210 LYS LYS B . n 
B 1 211 VAL 211 211 211 VAL VAL B . n 
B 1 212 PHE 212 212 212 PHE PHE B . n 
B 1 213 TYR 213 213 213 TYR TYR B . n 
B 1 214 ASP 214 214 214 ASP ASP B . n 
B 1 215 ALA 215 215 215 ALA ALA B . n 
B 1 216 THR 216 216 216 THR THR B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 CYS 218 218 218 CYS CYS B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 GLU 220 220 220 GLU GLU B . n 
B 1 221 ASN 221 221 221 ASN ASN B . n 
B 1 222 ALA 222 222 222 ALA ALA B . n 
B 1 223 TYR 223 223 223 TYR TYR B . n 
B 1 224 PHE 224 224 224 PHE PHE B . n 
B 1 225 ILE 225 225 225 ILE ILE B . n 
B 1 226 LYS 226 226 226 LYS LYS B . n 
B 1 227 GLU 227 227 227 GLU GLU B . n 
B 1 228 GLN 228 228 228 GLN GLN B . n 
B 1 229 GLU 229 229 229 GLU GLU B . n 
B 1 230 GLU 230 230 230 GLU GLU B . n 
B 1 231 GLY 231 231 231 GLY GLY B . n 
B 1 232 PHE 232 232 232 PHE PHE B . n 
B 1 233 GLU 233 233 233 GLU GLU B . n 
B 1 234 ASP 234 234 234 ASP ASP B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 ILE 237 237 237 ILE ILE B . n 
B 1 238 LYS 238 238 238 LYS LYS B . n 
B 1 239 ASP 239 239 239 ASP ASP B . n 
B 1 240 ILE 240 240 240 ILE ILE B . n 
B 1 241 VAL 241 241 241 VAL VAL B . n 
B 1 242 HIS 242 242 242 HIS HIS B . n 
B 1 243 GLU 243 243 243 GLU GLU B . n 
B 1 244 MET 244 244 244 MET MET B . n 
B 1 245 PHE 245 245 245 PHE PHE B . n 
B 1 246 SER 246 246 246 SER SER B . n 
B 1 247 TYR 247 247 247 TYR TYR B . n 
B 1 248 ALA 248 248 248 ALA ALA B . n 
B 1 249 ASP 249 249 249 ASP ASP B . n 
B 1 250 GLY 250 250 250 GLY GLY B . n 
B 1 251 CYS 251 251 251 CYS CYS B . n 
B 1 252 THR 252 252 252 THR THR B . n 
B 1 253 MET 253 253 253 MET MET B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 GLY 255 255 255 GLY GLY B . n 
B 1 256 LYS 256 256 256 LYS LYS B . n 
B 1 257 LLP 257 257 257 LLP LLP B . n 
B 1 258 ASP 258 258 258 ASP ASP B . n 
B 1 259 CYS 259 259 259 CYS CYS B . n 
B 1 260 LEU 260 260 260 LEU LEU B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 ASN 262 262 262 ASN ASN B . n 
B 1 263 ILE 263 263 263 ILE ILE B . n 
B 1 264 GLY 264 264 264 GLY GLY B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 PHE 266 266 266 PHE PHE B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 CYS 268 268 268 CYS CYS B . n 
B 1 269 MET 269 269 269 MET MET B . n 
B 1 270 ASN 270 270 270 ASN ASN B . n 
B 1 271 ASP 271 271 271 ASP ASP B . n 
B 1 272 ASP 272 272 272 ASP ASP B . n 
B 1 273 ASP 273 273 273 ASP ASP B . n 
B 1 274 MET 274 274 274 MET MET B . n 
B 1 275 PHE 275 275 275 PHE PHE B . n 
B 1 276 SER 276 276 276 SER SER B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 ALA 278 278 278 ALA ALA B . n 
B 1 279 ARG 279 279 279 ARG ARG B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 VAL 282 282 282 VAL VAL B . n 
B 1 283 VAL 283 283 283 VAL VAL B . n 
B 1 284 VAL 284 284 284 VAL VAL B . n 
B 1 285 TYR 285 285 285 TYR TYR B . n 
B 1 286 GLU 286 286 286 GLU GLU B . n 
B 1 287 GLY 287 287 287 GLY GLY B . n 
B 1 288 MET 288 288 288 MET MET B . n 
B 1 289 PRO 289 289 289 PRO PRO B . n 
B 1 290 SER 290 290 290 SER SER B . n 
B 1 291 TYR 291 291 291 TYR TYR B . n 
B 1 292 GLY 292 292 292 GLY GLY B . n 
B 1 293 GLY 293 293 293 GLY GLY B . n 
B 1 294 LEU 294 294 294 LEU LEU B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 ARG 297 297 297 ARG ARG B . n 
B 1 298 ASP 298 298 298 ASP ASP B . n 
B 1 299 MET 299 299 299 MET MET B . n 
B 1 300 GLU 300 300 300 GLU GLU B . n 
B 1 301 ALA 301 301 301 ALA ALA B . n 
B 1 302 MET 302 302 302 MET MET B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 ILE 304 304 304 ILE ILE B . n 
B 1 305 GLY 305 305 305 GLY GLY B . n 
B 1 306 LEU 306 306 306 LEU LEU B . n 
B 1 307 ARG 307 307 307 ARG ARG B . n 
B 1 308 GLU 308 308 308 GLU GLU B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 MET 310 310 310 MET MET B . n 
B 1 311 GLN 311 311 311 GLN GLN B . n 
B 1 312 PHE 312 312 312 PHE PHE B . n 
B 1 313 GLU 313 313 313 GLU GLU B . n 
B 1 314 TYR 314 314 314 TYR TYR B . n 
B 1 315 ILE 315 315 315 ILE ILE B . n 
B 1 316 GLU 316 316 316 GLU GLU B . n 
B 1 317 HIS 317 317 317 HIS HIS B . n 
B 1 318 ARG 318 318 318 ARG ARG B . n 
B 1 319 VAL 319 319 319 VAL VAL B . n 
B 1 320 LYS 320 320 320 LYS LYS B . n 
B 1 321 GLN 321 321 321 GLN GLN B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 TYR 324 324 324 TYR TYR B . n 
B 1 325 LEU 325 325 325 LEU LEU B . n 
B 1 326 GLY 326 326 326 GLY GLY B . n 
B 1 327 GLU 327 327 327 GLU GLU B . n 
B 1 328 LYS 328 328 328 LYS LYS B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 LYS 330 330 330 LYS LYS B . n 
B 1 331 ALA 331 331 331 ALA ALA B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 GLY 333 333 333 GLY GLY B . n 
B 1 334 VAL 334 334 334 VAL VAL B . n 
B 1 335 PRO 335 335 335 PRO PRO B . n 
B 1 336 ILE 336 336 336 ILE ILE B . n 
B 1 337 VAL 337 337 337 VAL VAL B . n 
B 1 338 GLU 338 338 338 GLU GLU B . n 
B 1 339 PRO 339 339 339 PRO PRO B . n 
B 1 340 VAL 340 340 340 VAL VAL B . n 
B 1 341 GLY 341 341 341 GLY GLY B . n 
B 1 342 GLY 342 342 342 GLY GLY B . n 
B 1 343 HIS 343 343 343 HIS HIS B . n 
B 1 344 ALA 344 344 344 ALA ALA B . n 
B 1 345 VAL 345 345 345 VAL VAL B . n 
B 1 346 PHE 346 346 346 PHE PHE B . n 
B 1 347 LEU 347 347 347 LEU LEU B . n 
B 1 348 ASP 348 348 348 ASP ASP B . n 
B 1 349 ALA 349 349 349 ALA ALA B . n 
B 1 350 ARG 350 350 350 ARG ARG B . n 
B 1 351 ARG 351 351 351 ARG ARG B . n 
B 1 352 PHE 352 352 352 PHE PHE B . n 
B 1 353 CYS 353 353 353 CYS CYS B . n 
B 1 354 PRO 354 354 354 PRO PRO B . n 
B 1 355 HIS 355 355 355 HIS HIS B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 THR 357 357 357 THR THR B . n 
B 1 358 GLN 358 358 358 GLN GLN B . n 
B 1 359 ASP 359 359 359 ASP ASP B . n 
B 1 360 GLU 360 360 360 GLU GLU B . n 
B 1 361 PHE 361 361 361 PHE PHE B . n 
B 1 362 PRO 362 362 362 PRO PRO B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 GLN 364 364 364 GLN GLN B . n 
B 1 365 SER 365 365 365 SER SER B . n 
B 1 366 LEU 366 366 366 LEU LEU B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 SER 369 369 369 SER SER B . n 
B 1 370 ILE 370 370 370 ILE ILE B . n 
B 1 371 TYR 371 371 371 TYR TYR B . n 
B 1 372 MET 372 372 372 MET MET B . n 
B 1 373 GLU 373 373 373 GLU GLU B . n 
B 1 374 THR 374 374 374 THR THR B . n 
B 1 375 GLY 375 375 375 GLY GLY B . n 
B 1 376 VAL 376 376 376 VAL VAL B . n 
B 1 377 ARG 377 377 377 ARG ARG B . n 
B 1 378 SER 378 378 378 SER SER B . n 
B 1 379 MET 379 379 379 MET MET B . n 
B 1 380 GLU 380 380 380 GLU GLU B . n 
B 1 381 ARG 381 381 381 ARG ARG B . n 
B 1 382 GLY 382 382 382 GLY GLY B . n 
B 1 383 ILE 383 383 383 ILE ILE B . n 
B 1 384 ILE 384 384 384 ILE ILE B . n 
B 1 385 SER 385 385 385 SER SER B . n 
B 1 386 ALA 386 386 386 ALA ALA B . n 
B 1 387 GLY 387 387 387 GLY GLY B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 ASN 389 389 389 ASN ASN B . n 
B 1 390 LYS 390 390 390 LYS LYS B . n 
B 1 391 GLU 391 391 391 GLU GLU B . n 
B 1 392 THR 392 392 392 THR THR B . n 
B 1 393 GLY 393 393 393 GLY GLY B . n 
B 1 394 ASP 394 394 394 ASP ASP B . n 
B 1 395 HIS 395 395 395 HIS HIS B . n 
B 1 396 HIS 396 396 396 HIS HIS B . n 
B 1 397 ARG 397 397 397 ARG ARG B . n 
B 1 398 PRO 398 398 398 PRO PRO B . n 
B 1 399 LYS 399 399 399 LYS LYS B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 GLU 401 401 401 GLU GLU B . n 
B 1 402 THR 402 402 402 THR THR B . n 
B 1 403 VAL 403 403 403 VAL VAL B . n 
B 1 404 ARG 404 404 404 ARG ARG B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 THR 406 406 406 THR THR B . n 
B 1 407 ILE 407 407 407 ILE ILE B . n 
B 1 408 PRO 408 408 408 PRO PRO B . n 
B 1 409 ARG 409 409 409 ARG ARG B . n 
B 1 410 ARG 410 410 410 ARG ARG B . n 
B 1 411 VAL 411 411 411 VAL VAL B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 THR 413 413 413 THR THR B . n 
B 1 414 TYR 414 414 414 TYR TYR B . n 
B 1 415 ALA 415 415 415 ALA ALA B . n 
B 1 416 HIS 416 416 416 HIS HIS B . n 
B 1 417 MET 417 417 417 MET MET B . n 
B 1 418 ASP 418 418 418 ASP ASP B . n 
B 1 419 LEU 419 419 419 LEU LEU B . n 
B 1 420 VAL 420 420 420 VAL VAL B . n 
B 1 421 ALA 421 421 421 ALA ALA B . n 
B 1 422 ASP 422 422 422 ASP ASP B . n 
B 1 423 GLY 423 423 423 GLY GLY B . n 
B 1 424 ILE 424 424 424 ILE ILE B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 LYS 426 426 426 LYS LYS B . n 
B 1 427 LEU 427 427 427 LEU LEU B . n 
B 1 428 PHE 428 428 428 PHE PHE B . n 
B 1 429 LYS 429 429 429 LYS LYS B . n 
B 1 430 HIS 430 430 430 HIS HIS B . n 
B 1 431 LYS 431 431 431 LYS LYS B . n 
B 1 432 GLU 432 432 432 GLU GLU B . n 
B 1 433 ASP 433 433 433 ASP ASP B . n 
B 1 434 ILE 434 434 434 ILE ILE B . n 
B 1 435 LYS 435 435 435 LYS LYS B . n 
B 1 436 GLY 436 436 436 GLY GLY B . n 
B 1 437 LEU 437 437 437 LEU LEU B . n 
B 1 438 LYS 438 438 438 LYS LYS B . n 
B 1 439 PHE 439 439 439 PHE PHE B . n 
B 1 440 VAL 440 440 440 VAL VAL B . n 
B 1 441 TYR 441 441 441 TYR TYR B . n 
B 1 442 GLU 442 442 442 GLU GLU B . n 
B 1 443 PRO 443 443 443 PRO PRO B . n 
B 1 444 LYS 444 444 444 LYS LYS B . n 
B 1 445 GLN 445 445 445 GLN GLN B . n 
B 1 446 LEU 446 446 446 LEU LEU B . n 
B 1 447 ARG 447 447 447 ARG ARG B . n 
B 1 448 PHE 448 448 448 PHE PHE B . n 
B 1 449 PHE 449 449 449 PHE PHE B . n 
B 1 450 THR 450 450 450 THR THR B . n 
B 1 451 ALA 451 451 451 ALA ALA B . n 
B 1 452 ARG 452 452 452 ARG ARG B . n 
B 1 453 PHE 453 453 453 PHE PHE B . n 
B 1 454 ASP 454 454 454 ASP ASP B . n 
B 1 455 TYR 455 455 455 TYR TYR B . n 
B 1 456 VAL 456 456 456 VAL VAL B . n 
B 1 457 HIS 457 457 457 HIS HIS B . n 
B 1 458 HIS 458 458 458 HIS HIS B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 34D 1   501 1   34D 34D A . 
D 2 34D 1   502 2   34D 34D A . 
E 3 K   1   503 1   K   K   A . 
F 3 K   1   501 2   K   K   B . 
G 4 HOH 1   601 638 HOH HOH A . 
G 4 HOH 2   602 90  HOH HOH A . 
G 4 HOH 3   603 289 HOH HOH A . 
G 4 HOH 4   604 370 HOH HOH A . 
G 4 HOH 5   605 380 HOH HOH A . 
G 4 HOH 6   606 439 HOH HOH A . 
G 4 HOH 7   607 542 HOH HOH A . 
G 4 HOH 8   608 253 HOH HOH A . 
G 4 HOH 9   609 529 HOH HOH A . 
G 4 HOH 10  610 221 HOH HOH A . 
G 4 HOH 11  611 408 HOH HOH A . 
G 4 HOH 12  612 441 HOH HOH A . 
G 4 HOH 13  613 300 HOH HOH A . 
G 4 HOH 14  614 95  HOH HOH A . 
G 4 HOH 15  615 363 HOH HOH A . 
G 4 HOH 16  616 339 HOH HOH A . 
G 4 HOH 17  617 305 HOH HOH A . 
G 4 HOH 18  618 670 HOH HOH A . 
G 4 HOH 19  619 82  HOH HOH A . 
G 4 HOH 20  620 85  HOH HOH A . 
G 4 HOH 21  621 544 HOH HOH A . 
G 4 HOH 22  622 437 HOH HOH A . 
G 4 HOH 23  623 45  HOH HOH A . 
G 4 HOH 24  624 574 HOH HOH A . 
G 4 HOH 25  625 372 HOH HOH A . 
G 4 HOH 26  626 314 HOH HOH A . 
G 4 HOH 27  627 350 HOH HOH A . 
G 4 HOH 28  628 642 HOH HOH A . 
G 4 HOH 29  629 450 HOH HOH A . 
G 4 HOH 30  630 628 HOH HOH A . 
G 4 HOH 31  631 428 HOH HOH A . 
G 4 HOH 32  632 121 HOH HOH A . 
G 4 HOH 33  633 139 HOH HOH A . 
G 4 HOH 34  634 203 HOH HOH A . 
G 4 HOH 35  635 464 HOH HOH A . 
G 4 HOH 36  636 199 HOH HOH A . 
G 4 HOH 37  637 347 HOH HOH A . 
G 4 HOH 38  638 566 HOH HOH A . 
G 4 HOH 39  639 573 HOH HOH A . 
G 4 HOH 40  640 202 HOH HOH A . 
G 4 HOH 41  641 8   HOH HOH A . 
G 4 HOH 42  642 49  HOH HOH A . 
G 4 HOH 43  643 43  HOH HOH A . 
G 4 HOH 44  644 226 HOH HOH A . 
G 4 HOH 45  645 236 HOH HOH A . 
G 4 HOH 46  646 230 HOH HOH A . 
G 4 HOH 47  647 181 HOH HOH A . 
G 4 HOH 48  648 59  HOH HOH A . 
G 4 HOH 49  649 33  HOH HOH A . 
G 4 HOH 50  650 247 HOH HOH A . 
G 4 HOH 51  651 599 HOH HOH A . 
G 4 HOH 52  652 641 HOH HOH A . 
G 4 HOH 53  653 419 HOH HOH A . 
G 4 HOH 54  654 268 HOH HOH A . 
G 4 HOH 55  655 267 HOH HOH A . 
G 4 HOH 56  656 10  HOH HOH A . 
G 4 HOH 57  657 647 HOH HOH A . 
G 4 HOH 58  658 366 HOH HOH A . 
G 4 HOH 59  659 191 HOH HOH A . 
G 4 HOH 60  660 75  HOH HOH A . 
G 4 HOH 61  661 123 HOH HOH A . 
G 4 HOH 62  662 204 HOH HOH A . 
G 4 HOH 63  663 617 HOH HOH A . 
G 4 HOH 64  664 518 HOH HOH A . 
G 4 HOH 65  665 636 HOH HOH A . 
G 4 HOH 66  666 254 HOH HOH A . 
G 4 HOH 67  667 32  HOH HOH A . 
G 4 HOH 68  668 206 HOH HOH A . 
G 4 HOH 69  669 277 HOH HOH A . 
G 4 HOH 70  670 1   HOH HOH A . 
G 4 HOH 71  671 249 HOH HOH A . 
G 4 HOH 72  672 175 HOH HOH A . 
G 4 HOH 73  673 92  HOH HOH A . 
G 4 HOH 74  674 467 HOH HOH A . 
G 4 HOH 75  675 29  HOH HOH A . 
G 4 HOH 76  676 84  HOH HOH A . 
G 4 HOH 77  677 22  HOH HOH A . 
G 4 HOH 78  678 498 HOH HOH A . 
G 4 HOH 79  679 444 HOH HOH A . 
G 4 HOH 80  680 397 HOH HOH A . 
G 4 HOH 81  681 160 HOH HOH A . 
G 4 HOH 82  682 44  HOH HOH A . 
G 4 HOH 83  683 141 HOH HOH A . 
G 4 HOH 84  684 117 HOH HOH A . 
G 4 HOH 85  685 443 HOH HOH A . 
G 4 HOH 86  686 402 HOH HOH A . 
G 4 HOH 87  687 568 HOH HOH A . 
G 4 HOH 88  688 20  HOH HOH A . 
G 4 HOH 89  689 184 HOH HOH A . 
G 4 HOH 90  690 34  HOH HOH A . 
G 4 HOH 91  691 466 HOH HOH A . 
G 4 HOH 92  692 88  HOH HOH A . 
G 4 HOH 93  693 240 HOH HOH A . 
G 4 HOH 94  694 86  HOH HOH A . 
G 4 HOH 95  695 353 HOH HOH A . 
G 4 HOH 96  696 368 HOH HOH A . 
G 4 HOH 97  697 126 HOH HOH A . 
G 4 HOH 98  698 216 HOH HOH A . 
G 4 HOH 99  699 19  HOH HOH A . 
G 4 HOH 100 700 319 HOH HOH A . 
G 4 HOH 101 701 153 HOH HOH A . 
G 4 HOH 102 702 134 HOH HOH A . 
G 4 HOH 103 703 156 HOH HOH A . 
G 4 HOH 104 704 405 HOH HOH A . 
G 4 HOH 105 705 62  HOH HOH A . 
G 4 HOH 106 706 387 HOH HOH A . 
G 4 HOH 107 707 625 HOH HOH A . 
G 4 HOH 108 708 169 HOH HOH A . 
G 4 HOH 109 709 263 HOH HOH A . 
G 4 HOH 110 710 78  HOH HOH A . 
G 4 HOH 111 711 262 HOH HOH A . 
G 4 HOH 112 712 375 HOH HOH A . 
G 4 HOH 113 713 233 HOH HOH A . 
G 4 HOH 114 714 48  HOH HOH A . 
G 4 HOH 115 715 104 HOH HOH A . 
G 4 HOH 116 716 173 HOH HOH A . 
G 4 HOH 117 717 480 HOH HOH A . 
G 4 HOH 118 718 320 HOH HOH A . 
G 4 HOH 119 719 394 HOH HOH A . 
G 4 HOH 120 720 426 HOH HOH A . 
G 4 HOH 121 721 166 HOH HOH A . 
G 4 HOH 122 722 577 HOH HOH A . 
G 4 HOH 123 723 404 HOH HOH A . 
G 4 HOH 124 724 135 HOH HOH A . 
G 4 HOH 125 725 264 HOH HOH A . 
G 4 HOH 126 726 63  HOH HOH A . 
G 4 HOH 127 727 634 HOH HOH A . 
G 4 HOH 128 728 159 HOH HOH A . 
G 4 HOH 129 729 9   HOH HOH A . 
G 4 HOH 130 730 110 HOH HOH A . 
G 4 HOH 131 731 580 HOH HOH A . 
G 4 HOH 132 732 456 HOH HOH A . 
G 4 HOH 133 733 115 HOH HOH A . 
G 4 HOH 134 734 52  HOH HOH A . 
G 4 HOH 135 735 73  HOH HOH A . 
G 4 HOH 136 736 351 HOH HOH A . 
G 4 HOH 137 737 189 HOH HOH A . 
G 4 HOH 138 738 551 HOH HOH A . 
G 4 HOH 139 739 25  HOH HOH A . 
G 4 HOH 140 740 127 HOH HOH A . 
G 4 HOH 141 741 68  HOH HOH A . 
G 4 HOH 142 742 116 HOH HOH A . 
G 4 HOH 143 743 519 HOH HOH A . 
G 4 HOH 144 744 103 HOH HOH A . 
G 4 HOH 145 745 246 HOH HOH A . 
G 4 HOH 146 746 38  HOH HOH A . 
G 4 HOH 147 747 210 HOH HOH A . 
G 4 HOH 148 748 165 HOH HOH A . 
G 4 HOH 149 749 355 HOH HOH A . 
G 4 HOH 150 750 327 HOH HOH A . 
G 4 HOH 151 751 148 HOH HOH A . 
G 4 HOH 152 752 194 HOH HOH A . 
G 4 HOH 153 753 30  HOH HOH A . 
G 4 HOH 154 754 11  HOH HOH A . 
G 4 HOH 155 755 436 HOH HOH A . 
G 4 HOH 156 756 46  HOH HOH A . 
G 4 HOH 157 757 448 HOH HOH A . 
G 4 HOH 158 758 61  HOH HOH A . 
G 4 HOH 159 759 451 HOH HOH A . 
G 4 HOH 160 760 188 HOH HOH A . 
G 4 HOH 161 761 554 HOH HOH A . 
G 4 HOH 162 762 120 HOH HOH A . 
G 4 HOH 163 763 91  HOH HOH A . 
G 4 HOH 164 764 149 HOH HOH A . 
G 4 HOH 165 765 186 HOH HOH A . 
G 4 HOH 166 766 536 HOH HOH A . 
G 4 HOH 167 767 195 HOH HOH A . 
G 4 HOH 168 768 535 HOH HOH A . 
G 4 HOH 169 769 342 HOH HOH A . 
G 4 HOH 170 770 108 HOH HOH A . 
G 4 HOH 171 771 87  HOH HOH A . 
G 4 HOH 172 772 183 HOH HOH A . 
G 4 HOH 173 773 357 HOH HOH A . 
G 4 HOH 174 774 555 HOH HOH A . 
G 4 HOH 175 775 130 HOH HOH A . 
G 4 HOH 176 776 546 HOH HOH A . 
G 4 HOH 177 777 214 HOH HOH A . 
G 4 HOH 178 778 12  HOH HOH A . 
G 4 HOH 179 779 463 HOH HOH A . 
G 4 HOH 180 780 81  HOH HOH A . 
G 4 HOH 181 781 316 HOH HOH A . 
G 4 HOH 182 782 507 HOH HOH A . 
G 4 HOH 183 783 297 HOH HOH A . 
G 4 HOH 184 784 489 HOH HOH A . 
G 4 HOH 185 785 72  HOH HOH A . 
G 4 HOH 186 786 224 HOH HOH A . 
G 4 HOH 187 787 138 HOH HOH A . 
G 4 HOH 188 788 152 HOH HOH A . 
G 4 HOH 189 789 113 HOH HOH A . 
G 4 HOH 190 790 39  HOH HOH A . 
G 4 HOH 191 791 500 HOH HOH A . 
G 4 HOH 192 792 385 HOH HOH A . 
G 4 HOH 193 793 458 HOH HOH A . 
G 4 HOH 194 794 582 HOH HOH A . 
G 4 HOH 195 795 648 HOH HOH A . 
G 4 HOH 196 796 172 HOH HOH A . 
G 4 HOH 197 797 335 HOH HOH A . 
G 4 HOH 198 798 593 HOH HOH A . 
G 4 HOH 199 799 15  HOH HOH A . 
G 4 HOH 200 800 257 HOH HOH A . 
G 4 HOH 201 801 486 HOH HOH A . 
G 4 HOH 202 802 383 HOH HOH A . 
G 4 HOH 203 803 109 HOH HOH A . 
G 4 HOH 204 804 182 HOH HOH A . 
G 4 HOH 205 805 136 HOH HOH A . 
G 4 HOH 206 806 446 HOH HOH A . 
G 4 HOH 207 807 657 HOH HOH A . 
G 4 HOH 208 808 239 HOH HOH A . 
G 4 HOH 209 809 271 HOH HOH A . 
G 4 HOH 210 810 427 HOH HOH A . 
G 4 HOH 211 811 235 HOH HOH A . 
G 4 HOH 212 812 301 HOH HOH A . 
G 4 HOH 213 813 462 HOH HOH A . 
G 4 HOH 214 814 293 HOH HOH A . 
G 4 HOH 215 815 492 HOH HOH A . 
G 4 HOH 216 816 559 HOH HOH A . 
G 4 HOH 217 817 50  HOH HOH A . 
G 4 HOH 218 818 661 HOH HOH A . 
G 4 HOH 219 819 396 HOH HOH A . 
G 4 HOH 220 820 241 HOH HOH A . 
G 4 HOH 221 821 144 HOH HOH A . 
G 4 HOH 222 822 99  HOH HOH A . 
G 4 HOH 223 823 418 HOH HOH A . 
G 4 HOH 224 824 561 HOH HOH A . 
G 4 HOH 225 825 212 HOH HOH A . 
G 4 HOH 226 826 540 HOH HOH A . 
G 4 HOH 227 827 490 HOH HOH A . 
G 4 HOH 228 828 360 HOH HOH A . 
G 4 HOH 229 829 567 HOH HOH A . 
G 4 HOH 230 830 358 HOH HOH A . 
G 4 HOH 231 831 548 HOH HOH A . 
G 4 HOH 232 832 569 HOH HOH A . 
G 4 HOH 233 833 292 HOH HOH A . 
G 4 HOH 234 834 541 HOH HOH A . 
G 4 HOH 235 835 155 HOH HOH A . 
G 4 HOH 236 836 499 HOH HOH A . 
G 4 HOH 237 837 468 HOH HOH A . 
G 4 HOH 238 838 600 HOH HOH A . 
G 4 HOH 239 839 570 HOH HOH A . 
G 4 HOH 240 840 591 HOH HOH A . 
G 4 HOH 241 841 472 HOH HOH A . 
G 4 HOH 242 842 517 HOH HOH A . 
G 4 HOH 243 843 552 HOH HOH A . 
G 4 HOH 244 844 208 HOH HOH A . 
G 4 HOH 245 845 220 HOH HOH A . 
G 4 HOH 246 846 237 HOH HOH A . 
G 4 HOH 247 847 256 HOH HOH A . 
G 4 HOH 248 848 461 HOH HOH A . 
G 4 HOH 249 849 475 HOH HOH A . 
G 4 HOH 250 850 684 HOH HOH A . 
G 4 HOH 251 851 494 HOH HOH A . 
G 4 HOH 252 852 409 HOH HOH A . 
G 4 HOH 253 853 644 HOH HOH A . 
G 4 HOH 254 854 639 HOH HOH A . 
G 4 HOH 255 855 425 HOH HOH A . 
G 4 HOH 256 856 114 HOH HOH A . 
G 4 HOH 257 857 322 HOH HOH A . 
G 4 HOH 258 858 170 HOH HOH A . 
G 4 HOH 259 859 669 HOH HOH A . 
G 4 HOH 260 860 400 HOH HOH A . 
G 4 HOH 261 861 340 HOH HOH A . 
G 4 HOH 262 862 550 HOH HOH A . 
G 4 HOH 263 863 278 HOH HOH A . 
G 4 HOH 264 864 294 HOH HOH A . 
G 4 HOH 265 865 470 HOH HOH A . 
G 4 HOH 266 866 423 HOH HOH A . 
G 4 HOH 267 867 674 HOH HOH A . 
G 4 HOH 268 868 459 HOH HOH A . 
G 4 HOH 269 869 623 HOH HOH A . 
G 4 HOH 270 870 352 HOH HOH A . 
G 4 HOH 271 871 359 HOH HOH A . 
G 4 HOH 272 872 424 HOH HOH A . 
G 4 HOH 273 873 658 HOH HOH A . 
G 4 HOH 274 874 590 HOH HOH A . 
G 4 HOH 275 875 653 HOH HOH A . 
G 4 HOH 276 876 282 HOH HOH A . 
G 4 HOH 277 877 407 HOH HOH A . 
G 4 HOH 278 878 325 HOH HOH A . 
G 4 HOH 279 879 447 HOH HOH A . 
G 4 HOH 280 880 510 HOH HOH A . 
G 4 HOH 281 881 524 HOH HOH A . 
H 4 HOH 1   601 142 HOH HOH B . 
H 4 HOH 2   602 545 HOH HOH B . 
H 4 HOH 3   603 244 HOH HOH B . 
H 4 HOH 4   604 365 HOH HOH B . 
H 4 HOH 5   605 356 HOH HOH B . 
H 4 HOH 6   606 488 HOH HOH B . 
H 4 HOH 7   607 362 HOH HOH B . 
H 4 HOH 8   608 395 HOH HOH B . 
H 4 HOH 9   609 234 HOH HOH B . 
H 4 HOH 10  610 432 HOH HOH B . 
H 4 HOH 11  611 414 HOH HOH B . 
H 4 HOH 12  612 338 HOH HOH B . 
H 4 HOH 13  613 196 HOH HOH B . 
H 4 HOH 14  614 40  HOH HOH B . 
H 4 HOH 15  615 83  HOH HOH B . 
H 4 HOH 16  616 47  HOH HOH B . 
H 4 HOH 17  617 41  HOH HOH B . 
H 4 HOH 18  618 557 HOH HOH B . 
H 4 HOH 19  619 304 HOH HOH B . 
H 4 HOH 20  620 255 HOH HOH B . 
H 4 HOH 21  621 637 HOH HOH B . 
H 4 HOH 22  622 631 HOH HOH B . 
H 4 HOH 23  623 281 HOH HOH B . 
H 4 HOH 24  624 60  HOH HOH B . 
H 4 HOH 25  625 632 HOH HOH B . 
H 4 HOH 26  626 96  HOH HOH B . 
H 4 HOH 27  627 71  HOH HOH B . 
H 4 HOH 28  628 295 HOH HOH B . 
H 4 HOH 29  629 215 HOH HOH B . 
H 4 HOH 30  630 361 HOH HOH B . 
H 4 HOH 31  631 318 HOH HOH B . 
H 4 HOH 32  632 129 HOH HOH B . 
H 4 HOH 33  633 23  HOH HOH B . 
H 4 HOH 34  634 630 HOH HOH B . 
H 4 HOH 35  635 93  HOH HOH B . 
H 4 HOH 36  636 307 HOH HOH B . 
H 4 HOH 37  637 664 HOH HOH B . 
H 4 HOH 38  638 198 HOH HOH B . 
H 4 HOH 39  639 504 HOH HOH B . 
H 4 HOH 40  640 177 HOH HOH B . 
H 4 HOH 41  641 369 HOH HOH B . 
H 4 HOH 42  642 228 HOH HOH B . 
H 4 HOH 43  643 650 HOH HOH B . 
H 4 HOH 44  644 51  HOH HOH B . 
H 4 HOH 45  645 341 HOH HOH B . 
H 4 HOH 46  646 128 HOH HOH B . 
H 4 HOH 47  647 106 HOH HOH B . 
H 4 HOH 48  648 64  HOH HOH B . 
H 4 HOH 49  649 309 HOH HOH B . 
H 4 HOH 50  650 411 HOH HOH B . 
H 4 HOH 51  651 2   HOH HOH B . 
H 4 HOH 52  652 323 HOH HOH B . 
H 4 HOH 53  653 14  HOH HOH B . 
H 4 HOH 54  654 55  HOH HOH B . 
H 4 HOH 55  655 388 HOH HOH B . 
H 4 HOH 56  656 17  HOH HOH B . 
H 4 HOH 57  657 250 HOH HOH B . 
H 4 HOH 58  658 242 HOH HOH B . 
H 4 HOH 59  659 344 HOH HOH B . 
H 4 HOH 60  660 65  HOH HOH B . 
H 4 HOH 61  661 376 HOH HOH B . 
H 4 HOH 62  662 36  HOH HOH B . 
H 4 HOH 63  663 211 HOH HOH B . 
H 4 HOH 64  664 58  HOH HOH B . 
H 4 HOH 65  665 384 HOH HOH B . 
H 4 HOH 66  666 31  HOH HOH B . 
H 4 HOH 67  667 274 HOH HOH B . 
H 4 HOH 68  668 157 HOH HOH B . 
H 4 HOH 69  669 174 HOH HOH B . 
H 4 HOH 70  670 54  HOH HOH B . 
H 4 HOH 71  671 209 HOH HOH B . 
H 4 HOH 72  672 218 HOH HOH B . 
H 4 HOH 73  673 315 HOH HOH B . 
H 4 HOH 74  674 207 HOH HOH B . 
H 4 HOH 75  675 80  HOH HOH B . 
H 4 HOH 76  676 42  HOH HOH B . 
H 4 HOH 77  677 4   HOH HOH B . 
H 4 HOH 78  678 35  HOH HOH B . 
H 4 HOH 79  679 213 HOH HOH B . 
H 4 HOH 80  680 449 HOH HOH B . 
H 4 HOH 81  681 460 HOH HOH B . 
H 4 HOH 82  682 484 HOH HOH B . 
H 4 HOH 83  683 6   HOH HOH B . 
H 4 HOH 84  684 27  HOH HOH B . 
H 4 HOH 85  685 79  HOH HOH B . 
H 4 HOH 86  686 276 HOH HOH B . 
H 4 HOH 87  687 509 HOH HOH B . 
H 4 HOH 88  688 21  HOH HOH B . 
H 4 HOH 89  689 105 HOH HOH B . 
H 4 HOH 90  690 205 HOH HOH B . 
H 4 HOH 91  691 167 HOH HOH B . 
H 4 HOH 92  692 168 HOH HOH B . 
H 4 HOH 93  693 28  HOH HOH B . 
H 4 HOH 94  694 56  HOH HOH B . 
H 4 HOH 95  695 137 HOH HOH B . 
H 4 HOH 96  696 269 HOH HOH B . 
H 4 HOH 97  697 145 HOH HOH B . 
H 4 HOH 98  698 158 HOH HOH B . 
H 4 HOH 99  699 53  HOH HOH B . 
H 4 HOH 100 700 97  HOH HOH B . 
H 4 HOH 101 701 495 HOH HOH B . 
H 4 HOH 102 702 124 HOH HOH B . 
H 4 HOH 103 703 37  HOH HOH B . 
H 4 HOH 104 704 311 HOH HOH B . 
H 4 HOH 105 705 146 HOH HOH B . 
H 4 HOH 106 706 112 HOH HOH B . 
H 4 HOH 107 707 125 HOH HOH B . 
H 4 HOH 108 708 102 HOH HOH B . 
H 4 HOH 109 709 187 HOH HOH B . 
H 4 HOH 110 710 16  HOH HOH B . 
H 4 HOH 111 711 275 HOH HOH B . 
H 4 HOH 112 712 421 HOH HOH B . 
H 4 HOH 113 713 279 HOH HOH B . 
H 4 HOH 114 714 151 HOH HOH B . 
H 4 HOH 115 715 272 HOH HOH B . 
H 4 HOH 116 716 143 HOH HOH B . 
H 4 HOH 117 717 76  HOH HOH B . 
H 4 HOH 118 718 286 HOH HOH B . 
H 4 HOH 119 719 150 HOH HOH B . 
H 4 HOH 120 720 161 HOH HOH B . 
H 4 HOH 121 721 537 HOH HOH B . 
H 4 HOH 122 722 140 HOH HOH B . 
H 4 HOH 123 723 171 HOH HOH B . 
H 4 HOH 124 724 201 HOH HOH B . 
H 4 HOH 125 725 70  HOH HOH B . 
H 4 HOH 126 726 3   HOH HOH B . 
H 4 HOH 127 727 336 HOH HOH B . 
H 4 HOH 128 728 132 HOH HOH B . 
H 4 HOH 129 729 7   HOH HOH B . 
H 4 HOH 130 730 24  HOH HOH B . 
H 4 HOH 131 731 217 HOH HOH B . 
H 4 HOH 132 732 197 HOH HOH B . 
H 4 HOH 133 733 393 HOH HOH B . 
H 4 HOH 134 734 18  HOH HOH B . 
H 4 HOH 135 735 445 HOH HOH B . 
H 4 HOH 136 736 26  HOH HOH B . 
H 4 HOH 137 737 229 HOH HOH B . 
H 4 HOH 138 738 313 HOH HOH B . 
H 4 HOH 139 739 179 HOH HOH B . 
H 4 HOH 140 740 74  HOH HOH B . 
H 4 HOH 141 741 100 HOH HOH B . 
H 4 HOH 142 742 558 HOH HOH B . 
H 4 HOH 143 743 633 HOH HOH B . 
H 4 HOH 144 744 503 HOH HOH B . 
H 4 HOH 145 745 349 HOH HOH B . 
H 4 HOH 146 746 515 HOH HOH B . 
H 4 HOH 147 747 312 HOH HOH B . 
H 4 HOH 148 748 299 HOH HOH B . 
H 4 HOH 149 749 119 HOH HOH B . 
H 4 HOH 150 750 13  HOH HOH B . 
H 4 HOH 151 751 180 HOH HOH B . 
H 4 HOH 152 752 147 HOH HOH B . 
H 4 HOH 153 753 581 HOH HOH B . 
H 4 HOH 154 754 596 HOH HOH B . 
H 4 HOH 155 755 308 HOH HOH B . 
H 4 HOH 156 756 67  HOH HOH B . 
H 4 HOH 157 757 283 HOH HOH B . 
H 4 HOH 158 758 479 HOH HOH B . 
H 4 HOH 159 759 193 HOH HOH B . 
H 4 HOH 160 760 538 HOH HOH B . 
H 4 HOH 161 761 98  HOH HOH B . 
H 4 HOH 162 762 107 HOH HOH B . 
H 4 HOH 163 763 649 HOH HOH B . 
H 4 HOH 164 764 258 HOH HOH B . 
H 4 HOH 165 765 663 HOH HOH B . 
H 4 HOH 166 766 656 HOH HOH B . 
H 4 HOH 167 767 454 HOH HOH B . 
H 4 HOH 168 768 94  HOH HOH B . 
H 4 HOH 169 769 348 HOH HOH B . 
H 4 HOH 170 770 287 HOH HOH B . 
H 4 HOH 171 771 273 HOH HOH B . 
H 4 HOH 172 772 310 HOH HOH B . 
H 4 HOH 173 773 317 HOH HOH B . 
H 4 HOH 174 774 285 HOH HOH B . 
H 4 HOH 175 775 261 HOH HOH B . 
H 4 HOH 176 776 379 HOH HOH B . 
H 4 HOH 177 777 185 HOH HOH B . 
H 4 HOH 178 778 190 HOH HOH B . 
H 4 HOH 179 779 610 HOH HOH B . 
H 4 HOH 180 780 5   HOH HOH B . 
H 4 HOH 181 781 131 HOH HOH B . 
H 4 HOH 182 782 457 HOH HOH B . 
H 4 HOH 183 783 528 HOH HOH B . 
H 4 HOH 184 784 643 HOH HOH B . 
H 4 HOH 185 785 346 HOH HOH B . 
H 4 HOH 186 786 620 HOH HOH B . 
H 4 HOH 187 787 626 HOH HOH B . 
H 4 HOH 188 788 392 HOH HOH B . 
H 4 HOH 189 789 303 HOH HOH B . 
H 4 HOH 190 790 291 HOH HOH B . 
H 4 HOH 191 791 354 HOH HOH B . 
H 4 HOH 192 792 386 HOH HOH B . 
H 4 HOH 193 793 69  HOH HOH B . 
H 4 HOH 194 794 478 HOH HOH B . 
H 4 HOH 195 795 403 HOH HOH B . 
H 4 HOH 196 796 440 HOH HOH B . 
H 4 HOH 197 797 89  HOH HOH B . 
H 4 HOH 198 798 284 HOH HOH B . 
H 4 HOH 199 799 493 HOH HOH B . 
H 4 HOH 200 800 290 HOH HOH B . 
H 4 HOH 201 801 200 HOH HOH B . 
H 4 HOH 202 802 332 HOH HOH B . 
H 4 HOH 203 803 337 HOH HOH B . 
H 4 HOH 204 804 296 HOH HOH B . 
H 4 HOH 205 805 176 HOH HOH B . 
H 4 HOH 206 806 530 HOH HOH B . 
H 4 HOH 207 807 260 HOH HOH B . 
H 4 HOH 208 808 288 HOH HOH B . 
H 4 HOH 209 809 266 HOH HOH B . 
H 4 HOH 210 810 465 HOH HOH B . 
H 4 HOH 211 811 162 HOH HOH B . 
H 4 HOH 212 812 232 HOH HOH B . 
H 4 HOH 213 813 222 HOH HOH B . 
H 4 HOH 214 814 227 HOH HOH B . 
H 4 HOH 215 815 442 HOH HOH B . 
H 4 HOH 216 816 371 HOH HOH B . 
H 4 HOH 217 817 481 HOH HOH B . 
H 4 HOH 218 818 57  HOH HOH B . 
H 4 HOH 219 819 192 HOH HOH B . 
H 4 HOH 220 820 178 HOH HOH B . 
H 4 HOH 221 821 434 HOH HOH B . 
H 4 HOH 222 822 398 HOH HOH B . 
H 4 HOH 223 823 164 HOH HOH B . 
H 4 HOH 224 824 331 HOH HOH B . 
H 4 HOH 225 825 587 HOH HOH B . 
H 4 HOH 226 826 133 HOH HOH B . 
H 4 HOH 227 827 77  HOH HOH B . 
H 4 HOH 228 828 66  HOH HOH B . 
H 4 HOH 229 829 163 HOH HOH B . 
H 4 HOH 230 830 251 HOH HOH B . 
H 4 HOH 231 831 118 HOH HOH B . 
H 4 HOH 232 832 373 HOH HOH B . 
H 4 HOH 233 833 324 HOH HOH B . 
H 4 HOH 234 834 259 HOH HOH B . 
H 4 HOH 235 835 302 HOH HOH B . 
H 4 HOH 236 836 321 HOH HOH B . 
H 4 HOH 237 837 688 HOH HOH B . 
H 4 HOH 238 838 487 HOH HOH B . 
H 4 HOH 239 839 482 HOH HOH B . 
H 4 HOH 240 840 265 HOH HOH B . 
H 4 HOH 241 841 243 HOH HOH B . 
H 4 HOH 242 842 624 HOH HOH B . 
H 4 HOH 243 843 539 HOH HOH B . 
H 4 HOH 244 844 413 HOH HOH B . 
H 4 HOH 245 845 473 HOH HOH B . 
H 4 HOH 246 846 219 HOH HOH B . 
H 4 HOH 247 847 579 HOH HOH B . 
H 4 HOH 248 848 377 HOH HOH B . 
H 4 HOH 249 849 401 HOH HOH B . 
H 4 HOH 250 850 595 HOH HOH B . 
H 4 HOH 251 851 223 HOH HOH B . 
H 4 HOH 252 852 549 HOH HOH B . 
H 4 HOH 253 853 420 HOH HOH B . 
H 4 HOH 254 854 575 HOH HOH B . 
H 4 HOH 255 855 589 HOH HOH B . 
H 4 HOH 256 856 343 HOH HOH B . 
H 4 HOH 257 857 621 HOH HOH B . 
H 4 HOH 258 858 665 HOH HOH B . 
H 4 HOH 259 859 471 HOH HOH B . 
H 4 HOH 260 860 101 HOH HOH B . 
H 4 HOH 261 861 238 HOH HOH B . 
H 4 HOH 262 862 374 HOH HOH B . 
H 4 HOH 263 863 389 HOH HOH B . 
H 4 HOH 264 864 497 HOH HOH B . 
H 4 HOH 265 865 280 HOH HOH B . 
H 4 HOH 266 866 584 HOH HOH B . 
H 4 HOH 267 867 364 HOH HOH B . 
H 4 HOH 268 868 252 HOH HOH B . 
H 4 HOH 269 869 560 HOH HOH B . 
H 4 HOH 270 870 245 HOH HOH B . 
H 4 HOH 271 871 225 HOH HOH B . 
H 4 HOH 272 872 483 HOH HOH B . 
H 4 HOH 273 873 477 HOH HOH B . 
H 4 HOH 274 874 562 HOH HOH B . 
H 4 HOH 275 875 367 HOH HOH B . 
H 4 HOH 276 876 399 HOH HOH B . 
H 4 HOH 277 877 122 HOH HOH B . 
H 4 HOH 278 878 635 HOH HOH B . 
H 4 HOH 279 879 248 HOH HOH B . 
H 4 HOH 280 880 564 HOH HOH B . 
H 4 HOH 281 881 563 HOH HOH B . 
H 4 HOH 282 882 556 HOH HOH B . 
H 4 HOH 283 883 583 HOH HOH B . 
H 4 HOH 284 884 452 HOH HOH B . 
H 4 HOH 285 885 231 HOH HOH B . 
H 4 HOH 286 886 333 HOH HOH B . 
H 4 HOH 287 887 438 HOH HOH B . 
H 4 HOH 288 888 523 HOH HOH B . 
H 4 HOH 289 889 412 HOH HOH B . 
H 4 HOH 290 890 547 HOH HOH B . 
H 4 HOH 291 891 334 HOH HOH B . 
H 4 HOH 292 892 602 HOH HOH B . 
H 4 HOH 293 893 431 HOH HOH B . 
H 4 HOH 294 894 651 HOH HOH B . 
H 4 HOH 295 895 111 HOH HOH B . 
H 4 HOH 296 896 429 HOH HOH B . 
H 4 HOH 297 897 430 HOH HOH B . 
H 4 HOH 298 898 453 HOH HOH B . 
H 4 HOH 299 899 455 HOH HOH B . 
H 4 HOH 300 900 154 HOH HOH B . 
H 4 HOH 301 901 598 HOH HOH B . 
H 4 HOH 302 902 330 HOH HOH B . 
H 4 HOH 303 903 571 HOH HOH B . 
H 4 HOH 304 904 390 HOH HOH B . 
H 4 HOH 305 905 378 HOH HOH B . 
H 4 HOH 306 906 605 HOH HOH B . 
H 4 HOH 307 907 576 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.9_1692 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot    ? ? ? .        5 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9J3U 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     111.422 
_cell.length_a_esd                 ? 
_cell.length_b                     155.664 
_cell.length_b_esd                 ? 
_cell.length_c                     58.919 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9J3U 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9J3U 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.42 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.24 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '3,5DHBA, HEPES-KOH pH 7.5, succinic acid, DMSO' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-12-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.980000 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PHOTON FACTORY BEAMLINE BL-17A' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.980000 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL-17A 
_diffrn_source.pdbx_synchrotron_site       'Photon Factory' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9J3U 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.83 
_reflns.d_resolution_low                               38.94 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     90546 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.35 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.4 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.95 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.83 
_reflns_shell.d_res_low                                     1.895 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             8483 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.802 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9J3U 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.830 
_refine.ls_d_res_low                             38.940 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     90534 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.34 
_refine.ls_percent_reflns_R_free                 2.21 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1519 
_refine.ls_R_factor_R_free                       0.1821 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1513 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      2EZ1 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 17.43 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.18 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.830 
_refine_hist.d_res_low                        38.940 
_refine_hist.number_atoms_solvent             588 
_refine_hist.number_atoms_total               7912 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7300 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         24 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  ? 7473  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.995  ? 10057 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 13.745 ? 2801  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.041  ? 1063  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.004  ? 1308  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.8300 1.8758 . . 133 5854 93.00  . . . . 0.2163 . . . . . . . . . . . 0.2589 
'X-RAY DIFFRACTION' 1.8758 1.9265 . . 139 6163 99.00  . . . . 0.2110 . . . . . . . . . . . 0.2642 
'X-RAY DIFFRACTION' 1.9265 1.9832 . . 142 6307 100.00 . . . . 0.1899 . . . . . . . . . . . 0.2650 
'X-RAY DIFFRACTION' 1.9832 2.0472 . . 142 6296 100.00 . . . . 0.1731 . . . . . . . . . . . 0.2133 
'X-RAY DIFFRACTION' 2.0472 2.1204 . . 142 6299 100.00 . . . . 0.1635 . . . . . . . . . . . 0.2159 
'X-RAY DIFFRACTION' 2.1204 2.2052 . . 143 6311 100.00 . . . . 0.1521 . . . . . . . . . . . 0.1817 
'X-RAY DIFFRACTION' 2.2052 2.3056 . . 143 6314 100.00 . . . . 0.1535 . . . . . . . . . . . 0.2152 
'X-RAY DIFFRACTION' 2.3056 2.4271 . . 142 6325 100.00 . . . . 0.1473 . . . . . . . . . . . 0.1587 
'X-RAY DIFFRACTION' 2.4271 2.5792 . . 144 6351 100.00 . . . . 0.1510 . . . . . . . . . . . 0.2035 
'X-RAY DIFFRACTION' 2.5792 2.7783 . . 143 6366 100.00 . . . . 0.1535 . . . . . . . . . . . 0.1986 
'X-RAY DIFFRACTION' 2.7783 3.0577 . . 145 6374 100.00 . . . . 0.1612 . . . . . . . . . . . 0.1672 
'X-RAY DIFFRACTION' 3.0577 3.5000 . . 144 6405 100.00 . . . . 0.1559 . . . . . . . . . . . 0.1907 
'X-RAY DIFFRACTION' 3.5000 4.4086 . . 146 6459 100.00 . . . . 0.1269 . . . . . . . . . . . 0.1561 
'X-RAY DIFFRACTION' 4.4086 38.940 . . 152 6710 100.00 . . . . 0.1343 . . . . . . . . . . . 0.1458 
# 
_struct.entry_id                     9J3U 
_struct.title                        'Crystal structure of tyrosine phenol-lyase in complex with 3,5-dihydroxybenzoic acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9J3U 
_struct_keywords.text            
;lyase, plp-dependent enzyme, pyridoxal-5'-phosphate, 3, 5-dihydroxybenzoic acid
;
_struct_keywords.pdbx_keywords   LYASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    J7TAF3_MORMO 
_struct_ref.pdbx_db_accession          J7TAF3 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MMYPAEPYRIKSVETVSMIPREERIKRMKEAGYNTFLLNSKDVYVDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFFHL
ERTVQELFGFKHIVPTHQGRGAENLLSSLAIKPGQYVAGNMYFTTTRYHQEKNGATFIDIVRDEAHDAGLDVKFKGNIDI
KKLEKLIAEKGAENIAYICLAVTVNLAGGQPVSMANMREVRQLCDKHGIKVFYDATRCVENAYFIKEQEEGFEDVSIKDI
VHEMFSYADGCTMSGKKDCLVNIGGFLCMNDDDMFSAARELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQFEYIEHRVK
QVRYLGEKLKAAGVPIVEPVGGHAVFLDARRFCPHLTQDEFPAQSLAASIYMETGVRSMERGIISAGRNKETGDHHRPKL
ETVRLTIPRRVYTYAHMDLVADGIIKLFKHKEDIKGLKFVYEPKQLRFFTARFDYV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9J3U A 1 ? 456 ? J7TAF3 1 ? 456 ? 1 456 
2 1 9J3U B 1 ? 456 ? J7TAF3 1 ? 456 ? 1 456 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9J3U ARG A 29  ? UNP J7TAF3 LYS 29 conflict         29  1 
1 9J3U HIS A 457 ? UNP J7TAF3 ?   ?  'expression tag' 457 2 
1 9J3U HIS A 458 ? UNP J7TAF3 ?   ?  'expression tag' 458 3 
2 9J3U ARG B 29  ? UNP J7TAF3 LYS 29 conflict         29  4 
2 9J3U HIS B 457 ? UNP J7TAF3 ?   ?  'expression tag' 457 5 
2 9J3U HIS B 458 ? UNP J7TAF3 ?   ?  'expression tag' 458 6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6280  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  33570 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 20  ? ALA A 31  ? PRO A 20  ALA A 31  1 ? 12 
HELX_P HELX_P2  AA2 ASN A 34  ? LEU A 38  ? ASN A 34  LEU A 38  5 ? 5  
HELX_P HELX_P3  AA3 ASN A 39  ? VAL A 43  ? ASN A 39  VAL A 43  5 ? 5  
HELX_P HELX_P4  AA4 SER A 57  ? MET A 65  ? SER A 57  MET A 65  1 ? 9  
HELX_P HELX_P5  AA5 SER A 74  ? GLY A 89  ? SER A 74  GLY A 89  1 ? 16 
HELX_P HELX_P6  AA6 GLN A 98  ? ILE A 111 ? GLN A 98  ILE A 111 1 ? 14 
HELX_P HELX_P7  AA7 PHE A 123 ? ASN A 133 ? PHE A 123 ASN A 133 1 ? 11 
HELX_P HELX_P8  AA8 ARG A 142 ? ASP A 147 ? ARG A 142 ASP A 147 5 ? 6  
HELX_P HELX_P9  AA9 ASP A 159 ? GLY A 171 ? ASP A 159 GLY A 171 1 ? 13 
HELX_P HELX_P10 AB1 SER A 193 ? GLY A 208 ? SER A 193 GLY A 208 1 ? 16 
HELX_P HELX_P11 AB2 ARG A 217 ? GLU A 229 ? ARG A 217 GLU A 229 1 ? 13 
HELX_P HELX_P12 AB3 SER A 236 ? TYR A 247 ? SER A 236 TYR A 247 1 ? 12 
HELX_P HELX_P13 AB4 ASP A 271 ? GLU A 286 ? ASP A 271 GLU A 286 1 ? 16 
HELX_P HELX_P14 AB5 ALA A 295 ? MET A 310 ? ALA A 295 MET A 310 1 ? 16 
HELX_P HELX_P15 AB6 GLN A 311 ? ALA A 332 ? GLN A 311 ALA A 332 1 ? 22 
HELX_P HELX_P16 AB7 ALA A 349 ? CYS A 353 ? ALA A 349 CYS A 353 1 ? 5  
HELX_P HELX_P17 AB8 THR A 357 ? GLU A 360 ? THR A 357 GLU A 360 5 ? 4  
HELX_P HELX_P18 AB9 PHE A 361 ? GLY A 375 ? PHE A 361 GLY A 375 1 ? 15 
HELX_P HELX_P19 AC1 GLY A 382 ? GLY A 387 ? GLY A 382 GLY A 387 1 ? 6  
HELX_P HELX_P20 AC2 THR A 413 ? HIS A 430 ? THR A 413 HIS A 430 1 ? 18 
HELX_P HELX_P21 AC3 LYS A 431 ? ILE A 434 ? LYS A 431 ILE A 434 5 ? 4  
HELX_P HELX_P22 AC4 LEU A 446 ? ALA A 451 ? LEU A 446 ALA A 451 1 ? 6  
HELX_P HELX_P23 AC5 PRO B 20  ? ALA B 31  ? PRO B 20  ALA B 31  1 ? 12 
HELX_P HELX_P24 AC6 ASN B 34  ? LEU B 38  ? ASN B 34  LEU B 38  5 ? 5  
HELX_P HELX_P25 AC7 ASN B 39  ? VAL B 43  ? ASN B 39  VAL B 43  5 ? 5  
HELX_P HELX_P26 AC8 SER B 57  ? MET B 65  ? SER B 57  MET B 65  1 ? 9  
HELX_P HELX_P27 AC9 SER B 74  ? GLY B 89  ? SER B 74  GLY B 89  1 ? 16 
HELX_P HELX_P28 AD1 GLN B 98  ? ILE B 111 ? GLN B 98  ILE B 111 1 ? 14 
HELX_P HELX_P29 AD2 PHE B 123 ? ASN B 133 ? PHE B 123 ASN B 133 1 ? 11 
HELX_P HELX_P30 AD3 ARG B 142 ? ASP B 147 ? ARG B 142 ASP B 147 5 ? 6  
HELX_P HELX_P31 AD4 ASP B 159 ? GLY B 171 ? ASP B 159 GLY B 171 1 ? 13 
HELX_P HELX_P32 AD5 SER B 193 ? GLY B 208 ? SER B 193 GLY B 208 1 ? 16 
HELX_P HELX_P33 AD6 ARG B 217 ? GLU B 229 ? ARG B 217 GLU B 229 1 ? 13 
HELX_P HELX_P34 AD7 SER B 236 ? SER B 246 ? SER B 236 SER B 246 1 ? 11 
HELX_P HELX_P35 AD8 ASP B 271 ? GLU B 286 ? ASP B 271 GLU B 286 1 ? 16 
HELX_P HELX_P36 AD9 ALA B 295 ? MET B 310 ? ALA B 295 MET B 310 1 ? 16 
HELX_P HELX_P37 AE1 GLN B 311 ? ALA B 332 ? GLN B 311 ALA B 332 1 ? 22 
HELX_P HELX_P38 AE2 ALA B 349 ? CYS B 353 ? ALA B 349 CYS B 353 1 ? 5  
HELX_P HELX_P39 AE3 THR B 357 ? GLU B 360 ? THR B 357 GLU B 360 5 ? 4  
HELX_P HELX_P40 AE4 PHE B 361 ? GLY B 375 ? PHE B 361 GLY B 375 1 ? 15 
HELX_P HELX_P41 AE5 GLY B 382 ? GLY B 387 ? GLY B 382 GLY B 387 1 ? 6  
HELX_P HELX_P42 AE6 THR B 413 ? HIS B 430 ? THR B 413 HIS B 430 1 ? 18 
HELX_P HELX_P43 AE7 LYS B 431 ? ILE B 434 ? LYS B 431 ILE B 434 5 ? 4  
HELX_P HELX_P44 AE8 LEU B 446 ? ALA B 451 ? LEU B 446 ALA B 451 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A LYS 256 C   ? ? ? 1_555 A LLP 257 N   ? ? A LYS 256 A LLP 257 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale2  covale both ? A LLP 257 C   ? ? ? 1_555 A ASP 258 N   ? ? A LLP 257 A ASP 258 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale3  covale both ? B LYS 256 C   ? ? ? 1_555 B LLP 257 N   ? ? B LYS 256 B LLP 257 1_555 ? ? ? ? ? ? ? 1.335 ? ? 
covale4  covale both ? B LLP 257 C   ? ? ? 1_555 B ASP 258 N   ? ? B LLP 257 B ASP 258 1_555 ? ? ? ? ? ? ? 1.332 ? ? 
metalc1  metalc ?    ? A GLY 52  O   ? ? ? 1_555 E K   .   K   ? ? A GLY 52  A K   503 1_555 ? ? ? ? ? ? ? 2.747 ? ? 
metalc2  metalc ?    ? A GLU 69  OE1 ? ? ? 1_555 F K   .   K   ? ? A GLU 69  B K   501 1_555 ? ? ? ? ? ? ? 2.718 ? ? 
metalc3  metalc ?    ? A ASN 262 O   ? ? ? 1_555 E K   .   K   ? ? A ASN 262 A K   503 1_555 ? ? ? ? ? ? ? 2.937 ? ? 
metalc4  metalc ?    ? E K   .   K   ? ? ? 1_555 G HOH .   O   ? ? A K   503 A HOH 763 1_555 ? ? ? ? ? ? ? 3.049 ? ? 
metalc5  metalc ?    ? E K   .   K   ? ? ? 1_555 B GLU 69  O   ? ? A K   503 B GLU 69  1_555 ? ? ? ? ? ? ? 3.424 ? ? 
metalc6  metalc ?    ? E K   .   K   ? ? ? 1_555 B GLU 69  OE1 ? ? A K   503 B GLU 69  1_555 ? ? ? ? ? ? ? 2.696 ? ? 
metalc7  metalc ?    ? E K   .   K   ? ? ? 1_555 H HOH .   O   ? ? A K   503 B HOH 694 1_555 ? ? ? ? ? ? ? 2.826 ? ? 
metalc8  metalc ?    ? E K   .   K   ? ? ? 1_555 H HOH .   O   ? ? A K   503 B HOH 703 1_555 ? ? ? ? ? ? ? 2.759 ? ? 
metalc9  metalc ?    ? G HOH .   O   ? ? ? 1_555 F K   .   K   ? ? A HOH 676 B K   501 1_555 ? ? ? ? ? ? ? 2.783 ? ? 
metalc10 metalc ?    ? B GLY 52  O   ? ? ? 1_555 F K   .   K   ? ? B GLY 52  B K   501 1_555 ? ? ? ? ? ? ? 2.774 ? ? 
metalc11 metalc ?    ? B ASN 262 O   ? ? ? 1_555 F K   .   K   ? ? B ASN 262 B K   501 1_555 ? ? ? ? ? ? ? 2.921 ? ? 
metalc12 metalc ?    ? F K   .   K   ? ? ? 1_555 H HOH .   O   ? ? B K   501 B HOH 666 1_555 ? ? ? ? ? ? ? 2.867 ? ? 
metalc13 metalc ?    ? F K   .   K   ? ? ? 1_555 H HOH .   O   ? ? B K   501 B HOH 797 1_555 ? ? ? ? ? ? ? 3.048 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? A ASN 262 ? A ASN 262 ? 1_555 82.2  ? 
2  O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? G HOH .   ? A HOH 763 ? 1_555 113.9 ? 
3  O   ? A ASN 262 ? A ASN 262 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? G HOH .   ? A HOH 763 ? 1_555 86.9  ? 
4  O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? B GLU 69  ? B GLU 69  ? 1_555 76.3  ? 
5  O   ? A ASN 262 ? A ASN 262 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? B GLU 69  ? B GLU 69  ? 1_555 158.0 ? 
6  O   ? G HOH .   ? A HOH 763 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? B GLU 69  ? B GLU 69  ? 1_555 97.2  ? 
7  O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 97.7  ? 
8  O   ? A ASN 262 ? A ASN 262 ? 1_555 K ? E K . ? A K 503 ? 1_555 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 101.4 ? 
9  O   ? G HOH .   ? A HOH 763 ? 1_555 K ? E K . ? A K 503 ? 1_555 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 148.2 ? 
10 O   ? B GLU 69  ? B GLU 69  ? 1_555 K ? E K . ? A K 503 ? 1_555 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 86.5  ? 
11 O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 694 ? 1_555 75.7  ? 
12 O   ? A ASN 262 ? A ASN 262 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 694 ? 1_555 118.7 ? 
13 O   ? G HOH .   ? A HOH 763 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 694 ? 1_555 54.2  ? 
14 O   ? B GLU 69  ? B GLU 69  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 694 ? 1_555 51.0  ? 
15 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 694 ? 1_555 137.4 ? 
16 O   ? A GLY 52  ? A GLY 52  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 165.7 ? 
17 O   ? A ASN 262 ? A ASN 262 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 109.1 ? 
18 O   ? G HOH .   ? A HOH 763 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 59.8  ? 
19 O   ? B GLU 69  ? B GLU 69  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 91.4  ? 
20 OE1 ? B GLU 69  ? B GLU 69  ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 88.7  ? 
21 O   ? H HOH .   ? B HOH 694 ? 1_555 K ? E K . ? A K 503 ? 1_555 O   ? H HOH .   ? B HOH 703 ? 1_555 91.0  ? 
22 OE1 ? A GLU 69  ? A GLU 69  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? G HOH .   ? A HOH 676 ? 1_555 84.2  ? 
23 OE1 ? A GLU 69  ? A GLU 69  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? B GLY 52  ? B GLY 52  ? 1_555 98.0  ? 
24 O   ? G HOH .   ? A HOH 676 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? B GLY 52  ? B GLY 52  ? 1_555 166.2 ? 
25 OE1 ? A GLU 69  ? A GLU 69  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? B ASN 262 ? B ASN 262 ? 1_555 102.9 ? 
26 O   ? G HOH .   ? A HOH 676 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? B ASN 262 ? B ASN 262 ? 1_555 110.5 ? 
27 O   ? B GLY 52  ? B GLY 52  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? B ASN 262 ? B ASN 262 ? 1_555 82.5  ? 
28 OE1 ? A GLU 69  ? A GLU 69  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 666 ? 1_555 135.6 ? 
29 O   ? G HOH .   ? A HOH 676 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 666 ? 1_555 94.8  ? 
30 O   ? B GLY 52  ? B GLY 52  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 666 ? 1_555 74.1  ? 
31 O   ? B ASN 262 ? B ASN 262 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 666 ? 1_555 118.6 ? 
32 OE1 ? A GLU 69  ? A GLU 69  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 797 ? 1_555 145.4 ? 
33 O   ? G HOH .   ? A HOH 676 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 797 ? 1_555 61.2  ? 
34 O   ? B GLY 52  ? B GLY 52  ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 797 ? 1_555 115.6 ? 
35 O   ? B ASN 262 ? B ASN 262 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 797 ? 1_555 90.3  ? 
36 O   ? H HOH .   ? B HOH 666 ? 1_555 K ? F K . ? B K 501 ? 1_555 O   ? H HOH .   ? B HOH 797 ? 1_555 54.3  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 LLP A 257 ? . . . . LLP A 257 ? 1_555 . . . . . . . LYS 1 LLP 'Pyridoxal phosphate' 'Named protein modification' 
2 LLP B 257 ? . . . . LLP B 257 ? 1_555 . . . . . . . LYS 1 LLP 'Pyridoxal phosphate' 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 182 A . ? VAL 182 A THR 183 A ? THR 183 A 1 -14.84 
2 GLU 338 A . ? GLU 338 A PRO 339 A ? PRO 339 A 1 -8.71  
3 VAL 182 B . ? VAL 182 B THR 183 B ? THR 183 B 1 -15.53 
4 GLU 338 B . ? GLU 338 B PRO 339 B ? PRO 339 B 1 -10.43 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 7 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 7 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA2 6 7 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? parallel      
AA6 4 5 ? parallel      
AA6 5 6 ? parallel      
AA6 6 7 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 45  ? ASP A 46  ? VAL A 45  ASP A 46  
AA1 2 VAL A 376 ? ARG A 377 ? VAL A 376 ARG A 377 
AA2 1 HIS A 92  ? THR A 96  ? HIS A 92  THR A 96  
AA2 2 GLY A 265 ? MET A 269 ? GLY A 265 MET A 269 
AA2 3 GLY A 250 ? SER A 254 ? GLY A 250 SER A 254 
AA2 4 VAL A 211 ? ASP A 214 ? VAL A 211 ASP A 214 
AA2 5 ILE A 175 ? ALA A 181 ? ILE A 175 ALA A 181 
AA2 6 TYR A 116 ? GLY A 119 ? TYR A 116 GLY A 119 
AA2 7 THR A 136 ? ASP A 139 ? THR A 136 ASP A 139 
AA3 1 ALA A 344 ? ASP A 348 ? ALA A 344 ASP A 348 
AA3 2 THR A 402 ? THR A 406 ? THR A 402 THR A 406 
AA3 3 MET A 379 ? ARG A 381 ? MET A 379 ARG A 381 
AA4 1 LEU A 437 ? TYR A 441 ? LEU A 437 TYR A 441 
AA4 2 ARG A 452 ? TYR A 455 ? ARG A 452 TYR A 455 
AA5 1 VAL B 45  ? ASP B 46  ? VAL B 45  ASP B 46  
AA5 2 VAL B 376 ? ARG B 377 ? VAL B 376 ARG B 377 
AA6 1 HIS B 92  ? THR B 96  ? HIS B 92  THR B 96  
AA6 2 GLY B 265 ? MET B 269 ? GLY B 265 MET B 269 
AA6 3 GLY B 250 ? SER B 254 ? GLY B 250 SER B 254 
AA6 4 VAL B 211 ? ASP B 214 ? VAL B 211 ASP B 214 
AA6 5 ILE B 175 ? ALA B 181 ? ILE B 175 ALA B 181 
AA6 6 TYR B 116 ? GLY B 119 ? TYR B 116 GLY B 119 
AA6 7 THR B 136 ? ASP B 139 ? THR B 136 ASP B 139 
AA7 1 ALA B 344 ? ASP B 348 ? ALA B 344 ASP B 348 
AA7 2 THR B 402 ? THR B 406 ? THR B 402 THR B 406 
AA7 3 MET B 379 ? ARG B 381 ? MET B 379 ARG B 381 
AA8 1 LEU B 437 ? TYR B 441 ? LEU B 437 TYR B 441 
AA8 2 ARG B 452 ? TYR B 455 ? ARG B 452 TYR B 455 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 45  ? N VAL A 45  O ARG A 377 ? O ARG A 377 
AA2 1 2 N VAL A 94  ? N VAL A 94  O LEU A 267 ? O LEU A 267 
AA2 2 3 O PHE A 266 ? O PHE A 266 N MET A 253 ? N MET A 253 
AA2 3 4 O THR A 252 ? O THR A 252 N TYR A 213 ? N TYR A 213 
AA2 4 5 O PHE A 212 ? O PHE A 212 N ILE A 178 ? N ILE A 178 
AA2 5 6 O CYS A 179 ? O CYS A 179 N ALA A 118 ? N ALA A 118 
AA2 6 7 N VAL A 117 ? N VAL A 117 O ILE A 138 ? O ILE A 138 
AA3 1 2 N VAL A 345 ? N VAL A 345 O LEU A 405 ? O LEU A 405 
AA3 2 3 O ARG A 404 ? O ARG A 404 N MET A 379 ? N MET A 379 
AA4 1 2 N VAL A 440 ? N VAL A 440 O ARG A 452 ? O ARG A 452 
AA5 1 2 N VAL B 45  ? N VAL B 45  O ARG B 377 ? O ARG B 377 
AA6 1 2 N VAL B 94  ? N VAL B 94  O LEU B 267 ? O LEU B 267 
AA6 2 3 O PHE B 266 ? O PHE B 266 N MET B 253 ? N MET B 253 
AA6 3 4 O THR B 252 ? O THR B 252 N TYR B 213 ? N TYR B 213 
AA6 4 5 O PHE B 212 ? O PHE B 212 N ILE B 178 ? N ILE B 178 
AA6 5 6 O CYS B 179 ? O CYS B 179 N ALA B 118 ? N ALA B 118 
AA6 6 7 N VAL B 117 ? N VAL B 117 O ILE B 138 ? O ILE B 138 
AA7 1 2 N VAL B 345 ? N VAL B 345 O LEU B 405 ? O LEU B 405 
AA7 2 3 O THR B 402 ? O THR B 402 N ARG B 381 ? N ARG B 381 
AA8 1 2 N VAL B 440 ? N VAL B 440 O ARG B 452 ? O ARG B 452 
# 
_pdbx_entry_details.entry_id                   9J3U 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O A HOH 727 ? ? O A HOH 843 ? ? 2.14 
2 1 O A HOH 768 ? ? O A HOH 853 ? ? 2.17 
3 1 O B HOH 755 ? ? O B HOH 852 ? ? 2.18 
4 1 O A HOH 601 ? ? O A HOH 707 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 7   ? ? -85.21  45.50   
2  1 GLN A 98  ? ? -164.20 -169.31 
3  1 MET A 121 ? ? 57.79   -164.36 
4  1 LLP A 257 ? ? -98.12  -100.26 
5  1 TYR A 291 ? ? -152.03 -25.76  
6  1 PHE A 361 ? ? 62.15   60.27   
7  1 PRO B 7   ? ? -83.39  46.72   
8  1 MET B 121 ? ? 62.47   -165.02 
9  1 LLP B 257 ? ? -99.67  -101.74 
10 1 TYR B 291 ? ? -154.05 -22.89  
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A LLP 257 A LLP 257 ? LYS 'modified residue' 
2 B LLP 257 B LLP 257 ? LYS 'modified residue' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       881 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.21 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     HIS 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      458 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    HIS 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     458 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
34D C2     C Y N 1   
34D C3     C Y N 2   
34D O3     O N N 3   
34D C4     C Y N 4   
34D C5     C Y N 5   
34D C1     C Y N 6   
34D C6     C Y N 7   
34D C      C N N 8   
34D O1     O N N 9   
34D O2     O N N 10  
34D O5     O N N 11  
34D H2     H N N 12  
34D H3     H N N 13  
34D H4     H N N 14  
34D H6     H N N 15  
34D HA     H N N 16  
34D H5     H N N 17  
ALA N      N N N 18  
ALA CA     C N S 19  
ALA C      C N N 20  
ALA O      O N N 21  
ALA CB     C N N 22  
ALA OXT    O N N 23  
ALA H      H N N 24  
ALA H2     H N N 25  
ALA HA     H N N 26  
ALA HB1    H N N 27  
ALA HB2    H N N 28  
ALA HB3    H N N 29  
ALA HXT    H N N 30  
ARG N      N N N 31  
ARG CA     C N S 32  
ARG C      C N N 33  
ARG O      O N N 34  
ARG CB     C N N 35  
ARG CG     C N N 36  
ARG CD     C N N 37  
ARG NE     N N N 38  
ARG CZ     C N N 39  
ARG NH1    N N N 40  
ARG NH2    N N N 41  
ARG OXT    O N N 42  
ARG H      H N N 43  
ARG H2     H N N 44  
ARG HA     H N N 45  
ARG HB2    H N N 46  
ARG HB3    H N N 47  
ARG HG2    H N N 48  
ARG HG3    H N N 49  
ARG HD2    H N N 50  
ARG HD3    H N N 51  
ARG HE     H N N 52  
ARG HH11   H N N 53  
ARG HH12   H N N 54  
ARG HH21   H N N 55  
ARG HH22   H N N 56  
ARG HXT    H N N 57  
ASN N      N N N 58  
ASN CA     C N S 59  
ASN C      C N N 60  
ASN O      O N N 61  
ASN CB     C N N 62  
ASN CG     C N N 63  
ASN OD1    O N N 64  
ASN ND2    N N N 65  
ASN OXT    O N N 66  
ASN H      H N N 67  
ASN H2     H N N 68  
ASN HA     H N N 69  
ASN HB2    H N N 70  
ASN HB3    H N N 71  
ASN HD21   H N N 72  
ASN HD22   H N N 73  
ASN HXT    H N N 74  
ASP N      N N N 75  
ASP CA     C N S 76  
ASP C      C N N 77  
ASP O      O N N 78  
ASP CB     C N N 79  
ASP CG     C N N 80  
ASP OD1    O N N 81  
ASP OD2    O N N 82  
ASP OXT    O N N 83  
ASP H      H N N 84  
ASP H2     H N N 85  
ASP HA     H N N 86  
ASP HB2    H N N 87  
ASP HB3    H N N 88  
ASP HD2    H N N 89  
ASP HXT    H N N 90  
CYS N      N N N 91  
CYS CA     C N R 92  
CYS C      C N N 93  
CYS O      O N N 94  
CYS CB     C N N 95  
CYS SG     S N N 96  
CYS OXT    O N N 97  
CYS H      H N N 98  
CYS H2     H N N 99  
CYS HA     H N N 100 
CYS HB2    H N N 101 
CYS HB3    H N N 102 
CYS HG     H N N 103 
CYS HXT    H N N 104 
GLN N      N N N 105 
GLN CA     C N S 106 
GLN C      C N N 107 
GLN O      O N N 108 
GLN CB     C N N 109 
GLN CG     C N N 110 
GLN CD     C N N 111 
GLN OE1    O N N 112 
GLN NE2    N N N 113 
GLN OXT    O N N 114 
GLN H      H N N 115 
GLN H2     H N N 116 
GLN HA     H N N 117 
GLN HB2    H N N 118 
GLN HB3    H N N 119 
GLN HG2    H N N 120 
GLN HG3    H N N 121 
GLN HE21   H N N 122 
GLN HE22   H N N 123 
GLN HXT    H N N 124 
GLU N      N N N 125 
GLU CA     C N S 126 
GLU C      C N N 127 
GLU O      O N N 128 
GLU CB     C N N 129 
GLU CG     C N N 130 
GLU CD     C N N 131 
GLU OE1    O N N 132 
GLU OE2    O N N 133 
GLU OXT    O N N 134 
GLU H      H N N 135 
GLU H2     H N N 136 
GLU HA     H N N 137 
GLU HB2    H N N 138 
GLU HB3    H N N 139 
GLU HG2    H N N 140 
GLU HG3    H N N 141 
GLU HE2    H N N 142 
GLU HXT    H N N 143 
GLY N      N N N 144 
GLY CA     C N N 145 
GLY C      C N N 146 
GLY O      O N N 147 
GLY OXT    O N N 148 
GLY H      H N N 149 
GLY H2     H N N 150 
GLY HA2    H N N 151 
GLY HA3    H N N 152 
GLY HXT    H N N 153 
HIS N      N N N 154 
HIS CA     C N S 155 
HIS C      C N N 156 
HIS O      O N N 157 
HIS CB     C N N 158 
HIS CG     C Y N 159 
HIS ND1    N Y N 160 
HIS CD2    C Y N 161 
HIS CE1    C Y N 162 
HIS NE2    N Y N 163 
HIS OXT    O N N 164 
HIS H      H N N 165 
HIS H2     H N N 166 
HIS HA     H N N 167 
HIS HB2    H N N 168 
HIS HB3    H N N 169 
HIS HD1    H N N 170 
HIS HD2    H N N 171 
HIS HE1    H N N 172 
HIS HE2    H N N 173 
HIS HXT    H N N 174 
HOH O      O N N 175 
HOH H1     H N N 176 
HOH H2     H N N 177 
ILE N      N N N 178 
ILE CA     C N S 179 
ILE C      C N N 180 
ILE O      O N N 181 
ILE CB     C N S 182 
ILE CG1    C N N 183 
ILE CG2    C N N 184 
ILE CD1    C N N 185 
ILE OXT    O N N 186 
ILE H      H N N 187 
ILE H2     H N N 188 
ILE HA     H N N 189 
ILE HB     H N N 190 
ILE HG12   H N N 191 
ILE HG13   H N N 192 
ILE HG21   H N N 193 
ILE HG22   H N N 194 
ILE HG23   H N N 195 
ILE HD11   H N N 196 
ILE HD12   H N N 197 
ILE HD13   H N N 198 
ILE HXT    H N N 199 
K   K      K N N 200 
LEU N      N N N 201 
LEU CA     C N S 202 
LEU C      C N N 203 
LEU O      O N N 204 
LEU CB     C N N 205 
LEU CG     C N N 206 
LEU CD1    C N N 207 
LEU CD2    C N N 208 
LEU OXT    O N N 209 
LEU H      H N N 210 
LEU H2     H N N 211 
LEU HA     H N N 212 
LEU HB2    H N N 213 
LEU HB3    H N N 214 
LEU HG     H N N 215 
LEU HD11   H N N 216 
LEU HD12   H N N 217 
LEU HD13   H N N 218 
LEU HD21   H N N 219 
LEU HD22   H N N 220 
LEU HD23   H N N 221 
LEU HXT    H N N 222 
LLP N1     N Y N 223 
LLP C2     C Y N 224 
LLP "C2'"  C N N 225 
LLP C3     C Y N 226 
LLP O3     O N N 227 
LLP C4     C Y N 228 
LLP "C4'"  C N N 229 
LLP C5     C Y N 230 
LLP C6     C Y N 231 
LLP "C5'"  C N N 232 
LLP OP4    O N N 233 
LLP P      P N N 234 
LLP OP1    O N N 235 
LLP OP2    O N N 236 
LLP OP3    O N N 237 
LLP N      N N N 238 
LLP CA     C N S 239 
LLP CB     C N N 240 
LLP CG     C N N 241 
LLP CD     C N N 242 
LLP CE     C N N 243 
LLP NZ     N N N 244 
LLP C      C N N 245 
LLP O      O N N 246 
LLP OXT    O N N 247 
LLP "H2'1" H N N 248 
LLP "H2'2" H N N 249 
LLP "H2'3" H N N 250 
LLP HO3    H N N 251 
LLP "H4'1" H N N 252 
LLP H6     H N N 253 
LLP "H5'1" H N N 254 
LLP "H5'2" H N N 255 
LLP HOP2   H N N 256 
LLP HOP3   H N N 257 
LLP H      H N N 258 
LLP H2     H N N 259 
LLP HA     H N N 260 
LLP HB2    H N N 261 
LLP HB3    H N N 262 
LLP HG2    H N N 263 
LLP HG3    H N N 264 
LLP HD2    H N N 265 
LLP HD3    H N N 266 
LLP HE2    H N N 267 
LLP HE3    H N N 268 
LLP HXT    H N N 269 
LYS N      N N N 270 
LYS CA     C N S 271 
LYS C      C N N 272 
LYS O      O N N 273 
LYS CB     C N N 274 
LYS CG     C N N 275 
LYS CD     C N N 276 
LYS CE     C N N 277 
LYS NZ     N N N 278 
LYS OXT    O N N 279 
LYS H      H N N 280 
LYS H2     H N N 281 
LYS HA     H N N 282 
LYS HB2    H N N 283 
LYS HB3    H N N 284 
LYS HG2    H N N 285 
LYS HG3    H N N 286 
LYS HD2    H N N 287 
LYS HD3    H N N 288 
LYS HE2    H N N 289 
LYS HE3    H N N 290 
LYS HZ1    H N N 291 
LYS HZ2    H N N 292 
LYS HZ3    H N N 293 
LYS HXT    H N N 294 
MET N      N N N 295 
MET CA     C N S 296 
MET C      C N N 297 
MET O      O N N 298 
MET CB     C N N 299 
MET CG     C N N 300 
MET SD     S N N 301 
MET CE     C N N 302 
MET OXT    O N N 303 
MET H      H N N 304 
MET H2     H N N 305 
MET HA     H N N 306 
MET HB2    H N N 307 
MET HB3    H N N 308 
MET HG2    H N N 309 
MET HG3    H N N 310 
MET HE1    H N N 311 
MET HE2    H N N 312 
MET HE3    H N N 313 
MET HXT    H N N 314 
PHE N      N N N 315 
PHE CA     C N S 316 
PHE C      C N N 317 
PHE O      O N N 318 
PHE CB     C N N 319 
PHE CG     C Y N 320 
PHE CD1    C Y N 321 
PHE CD2    C Y N 322 
PHE CE1    C Y N 323 
PHE CE2    C Y N 324 
PHE CZ     C Y N 325 
PHE OXT    O N N 326 
PHE H      H N N 327 
PHE H2     H N N 328 
PHE HA     H N N 329 
PHE HB2    H N N 330 
PHE HB3    H N N 331 
PHE HD1    H N N 332 
PHE HD2    H N N 333 
PHE HE1    H N N 334 
PHE HE2    H N N 335 
PHE HZ     H N N 336 
PHE HXT    H N N 337 
PRO N      N N N 338 
PRO CA     C N S 339 
PRO C      C N N 340 
PRO O      O N N 341 
PRO CB     C N N 342 
PRO CG     C N N 343 
PRO CD     C N N 344 
PRO OXT    O N N 345 
PRO H      H N N 346 
PRO HA     H N N 347 
PRO HB2    H N N 348 
PRO HB3    H N N 349 
PRO HG2    H N N 350 
PRO HG3    H N N 351 
PRO HD2    H N N 352 
PRO HD3    H N N 353 
PRO HXT    H N N 354 
SER N      N N N 355 
SER CA     C N S 356 
SER C      C N N 357 
SER O      O N N 358 
SER CB     C N N 359 
SER OG     O N N 360 
SER OXT    O N N 361 
SER H      H N N 362 
SER H2     H N N 363 
SER HA     H N N 364 
SER HB2    H N N 365 
SER HB3    H N N 366 
SER HG     H N N 367 
SER HXT    H N N 368 
THR N      N N N 369 
THR CA     C N S 370 
THR C      C N N 371 
THR O      O N N 372 
THR CB     C N R 373 
THR OG1    O N N 374 
THR CG2    C N N 375 
THR OXT    O N N 376 
THR H      H N N 377 
THR H2     H N N 378 
THR HA     H N N 379 
THR HB     H N N 380 
THR HG1    H N N 381 
THR HG21   H N N 382 
THR HG22   H N N 383 
THR HG23   H N N 384 
THR HXT    H N N 385 
TRP N      N N N 386 
TRP CA     C N S 387 
TRP C      C N N 388 
TRP O      O N N 389 
TRP CB     C N N 390 
TRP CG     C Y N 391 
TRP CD1    C Y N 392 
TRP CD2    C Y N 393 
TRP NE1    N Y N 394 
TRP CE2    C Y N 395 
TRP CE3    C Y N 396 
TRP CZ2    C Y N 397 
TRP CZ3    C Y N 398 
TRP CH2    C Y N 399 
TRP OXT    O N N 400 
TRP H      H N N 401 
TRP H2     H N N 402 
TRP HA     H N N 403 
TRP HB2    H N N 404 
TRP HB3    H N N 405 
TRP HD1    H N N 406 
TRP HE1    H N N 407 
TRP HE3    H N N 408 
TRP HZ2    H N N 409 
TRP HZ3    H N N 410 
TRP HH2    H N N 411 
TRP HXT    H N N 412 
TYR N      N N N 413 
TYR CA     C N S 414 
TYR C      C N N 415 
TYR O      O N N 416 
TYR CB     C N N 417 
TYR CG     C Y N 418 
TYR CD1    C Y N 419 
TYR CD2    C Y N 420 
TYR CE1    C Y N 421 
TYR CE2    C Y N 422 
TYR CZ     C Y N 423 
TYR OH     O N N 424 
TYR OXT    O N N 425 
TYR H      H N N 426 
TYR H2     H N N 427 
TYR HA     H N N 428 
TYR HB2    H N N 429 
TYR HB3    H N N 430 
TYR HD1    H N N 431 
TYR HD2    H N N 432 
TYR HE1    H N N 433 
TYR HE2    H N N 434 
TYR HH     H N N 435 
TYR HXT    H N N 436 
VAL N      N N N 437 
VAL CA     C N S 438 
VAL C      C N N 439 
VAL O      O N N 440 
VAL CB     C N N 441 
VAL CG1    C N N 442 
VAL CG2    C N N 443 
VAL OXT    O N N 444 
VAL H      H N N 445 
VAL H2     H N N 446 
VAL HA     H N N 447 
VAL HB     H N N 448 
VAL HG11   H N N 449 
VAL HG12   H N N 450 
VAL HG13   H N N 451 
VAL HG21   H N N 452 
VAL HG22   H N N 453 
VAL HG23   H N N 454 
VAL HXT    H N N 455 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
34D C2    C3     doub Y N 1   
34D C2    C1     sing Y N 2   
34D C2    H2     sing N N 3   
34D C3    O3     sing N N 4   
34D C3    C4     sing Y N 5   
34D O3    H3     sing N N 6   
34D C4    C5     doub Y N 7   
34D C4    H4     sing N N 8   
34D C5    C6     sing Y N 9   
34D C5    O5     sing N N 10  
34D C1    C6     doub Y N 11  
34D C1    C      sing N N 12  
34D C6    H6     sing N N 13  
34D C     O1     doub N N 14  
34D C     O2     sing N N 15  
34D O2    HA     sing N N 16  
34D O5    H5     sing N N 17  
ALA N     CA     sing N N 18  
ALA N     H      sing N N 19  
ALA N     H2     sing N N 20  
ALA CA    C      sing N N 21  
ALA CA    CB     sing N N 22  
ALA CA    HA     sing N N 23  
ALA C     O      doub N N 24  
ALA C     OXT    sing N N 25  
ALA CB    HB1    sing N N 26  
ALA CB    HB2    sing N N 27  
ALA CB    HB3    sing N N 28  
ALA OXT   HXT    sing N N 29  
ARG N     CA     sing N N 30  
ARG N     H      sing N N 31  
ARG N     H2     sing N N 32  
ARG CA    C      sing N N 33  
ARG CA    CB     sing N N 34  
ARG CA    HA     sing N N 35  
ARG C     O      doub N N 36  
ARG C     OXT    sing N N 37  
ARG CB    CG     sing N N 38  
ARG CB    HB2    sing N N 39  
ARG CB    HB3    sing N N 40  
ARG CG    CD     sing N N 41  
ARG CG    HG2    sing N N 42  
ARG CG    HG3    sing N N 43  
ARG CD    NE     sing N N 44  
ARG CD    HD2    sing N N 45  
ARG CD    HD3    sing N N 46  
ARG NE    CZ     sing N N 47  
ARG NE    HE     sing N N 48  
ARG CZ    NH1    sing N N 49  
ARG CZ    NH2    doub N N 50  
ARG NH1   HH11   sing N N 51  
ARG NH1   HH12   sing N N 52  
ARG NH2   HH21   sing N N 53  
ARG NH2   HH22   sing N N 54  
ARG OXT   HXT    sing N N 55  
ASN N     CA     sing N N 56  
ASN N     H      sing N N 57  
ASN N     H2     sing N N 58  
ASN CA    C      sing N N 59  
ASN CA    CB     sing N N 60  
ASN CA    HA     sing N N 61  
ASN C     O      doub N N 62  
ASN C     OXT    sing N N 63  
ASN CB    CG     sing N N 64  
ASN CB    HB2    sing N N 65  
ASN CB    HB3    sing N N 66  
ASN CG    OD1    doub N N 67  
ASN CG    ND2    sing N N 68  
ASN ND2   HD21   sing N N 69  
ASN ND2   HD22   sing N N 70  
ASN OXT   HXT    sing N N 71  
ASP N     CA     sing N N 72  
ASP N     H      sing N N 73  
ASP N     H2     sing N N 74  
ASP CA    C      sing N N 75  
ASP CA    CB     sing N N 76  
ASP CA    HA     sing N N 77  
ASP C     O      doub N N 78  
ASP C     OXT    sing N N 79  
ASP CB    CG     sing N N 80  
ASP CB    HB2    sing N N 81  
ASP CB    HB3    sing N N 82  
ASP CG    OD1    doub N N 83  
ASP CG    OD2    sing N N 84  
ASP OD2   HD2    sing N N 85  
ASP OXT   HXT    sing N N 86  
CYS N     CA     sing N N 87  
CYS N     H      sing N N 88  
CYS N     H2     sing N N 89  
CYS CA    C      sing N N 90  
CYS CA    CB     sing N N 91  
CYS CA    HA     sing N N 92  
CYS C     O      doub N N 93  
CYS C     OXT    sing N N 94  
CYS CB    SG     sing N N 95  
CYS CB    HB2    sing N N 96  
CYS CB    HB3    sing N N 97  
CYS SG    HG     sing N N 98  
CYS OXT   HXT    sing N N 99  
GLN N     CA     sing N N 100 
GLN N     H      sing N N 101 
GLN N     H2     sing N N 102 
GLN CA    C      sing N N 103 
GLN CA    CB     sing N N 104 
GLN CA    HA     sing N N 105 
GLN C     O      doub N N 106 
GLN C     OXT    sing N N 107 
GLN CB    CG     sing N N 108 
GLN CB    HB2    sing N N 109 
GLN CB    HB3    sing N N 110 
GLN CG    CD     sing N N 111 
GLN CG    HG2    sing N N 112 
GLN CG    HG3    sing N N 113 
GLN CD    OE1    doub N N 114 
GLN CD    NE2    sing N N 115 
GLN NE2   HE21   sing N N 116 
GLN NE2   HE22   sing N N 117 
GLN OXT   HXT    sing N N 118 
GLU N     CA     sing N N 119 
GLU N     H      sing N N 120 
GLU N     H2     sing N N 121 
GLU CA    C      sing N N 122 
GLU CA    CB     sing N N 123 
GLU CA    HA     sing N N 124 
GLU C     O      doub N N 125 
GLU C     OXT    sing N N 126 
GLU CB    CG     sing N N 127 
GLU CB    HB2    sing N N 128 
GLU CB    HB3    sing N N 129 
GLU CG    CD     sing N N 130 
GLU CG    HG2    sing N N 131 
GLU CG    HG3    sing N N 132 
GLU CD    OE1    doub N N 133 
GLU CD    OE2    sing N N 134 
GLU OE2   HE2    sing N N 135 
GLU OXT   HXT    sing N N 136 
GLY N     CA     sing N N 137 
GLY N     H      sing N N 138 
GLY N     H2     sing N N 139 
GLY CA    C      sing N N 140 
GLY CA    HA2    sing N N 141 
GLY CA    HA3    sing N N 142 
GLY C     O      doub N N 143 
GLY C     OXT    sing N N 144 
GLY OXT   HXT    sing N N 145 
HIS N     CA     sing N N 146 
HIS N     H      sing N N 147 
HIS N     H2     sing N N 148 
HIS CA    C      sing N N 149 
HIS CA    CB     sing N N 150 
HIS CA    HA     sing N N 151 
HIS C     O      doub N N 152 
HIS C     OXT    sing N N 153 
HIS CB    CG     sing N N 154 
HIS CB    HB2    sing N N 155 
HIS CB    HB3    sing N N 156 
HIS CG    ND1    sing Y N 157 
HIS CG    CD2    doub Y N 158 
HIS ND1   CE1    doub Y N 159 
HIS ND1   HD1    sing N N 160 
HIS CD2   NE2    sing Y N 161 
HIS CD2   HD2    sing N N 162 
HIS CE1   NE2    sing Y N 163 
HIS CE1   HE1    sing N N 164 
HIS NE2   HE2    sing N N 165 
HIS OXT   HXT    sing N N 166 
HOH O     H1     sing N N 167 
HOH O     H2     sing N N 168 
ILE N     CA     sing N N 169 
ILE N     H      sing N N 170 
ILE N     H2     sing N N 171 
ILE CA    C      sing N N 172 
ILE CA    CB     sing N N 173 
ILE CA    HA     sing N N 174 
ILE C     O      doub N N 175 
ILE C     OXT    sing N N 176 
ILE CB    CG1    sing N N 177 
ILE CB    CG2    sing N N 178 
ILE CB    HB     sing N N 179 
ILE CG1   CD1    sing N N 180 
ILE CG1   HG12   sing N N 181 
ILE CG1   HG13   sing N N 182 
ILE CG2   HG21   sing N N 183 
ILE CG2   HG22   sing N N 184 
ILE CG2   HG23   sing N N 185 
ILE CD1   HD11   sing N N 186 
ILE CD1   HD12   sing N N 187 
ILE CD1   HD13   sing N N 188 
ILE OXT   HXT    sing N N 189 
LEU N     CA     sing N N 190 
LEU N     H      sing N N 191 
LEU N     H2     sing N N 192 
LEU CA    C      sing N N 193 
LEU CA    CB     sing N N 194 
LEU CA    HA     sing N N 195 
LEU C     O      doub N N 196 
LEU C     OXT    sing N N 197 
LEU CB    CG     sing N N 198 
LEU CB    HB2    sing N N 199 
LEU CB    HB3    sing N N 200 
LEU CG    CD1    sing N N 201 
LEU CG    CD2    sing N N 202 
LEU CG    HG     sing N N 203 
LEU CD1   HD11   sing N N 204 
LEU CD1   HD12   sing N N 205 
LEU CD1   HD13   sing N N 206 
LEU CD2   HD21   sing N N 207 
LEU CD2   HD22   sing N N 208 
LEU CD2   HD23   sing N N 209 
LEU OXT   HXT    sing N N 210 
LLP N1    C2     doub Y N 211 
LLP N1    C6     sing Y N 212 
LLP C2    "C2'"  sing N N 213 
LLP C2    C3     sing Y N 214 
LLP C3    O3     sing N N 215 
LLP C3    C4     doub Y N 216 
LLP C4    "C4'"  sing N N 217 
LLP C4    C5     sing Y N 218 
LLP "C4'" NZ     doub N N 219 
LLP C5    C6     doub Y N 220 
LLP C5    "C5'"  sing N N 221 
LLP "C5'" OP4    sing N N 222 
LLP OP4   P      sing N N 223 
LLP P     OP1    doub N N 224 
LLP P     OP2    sing N N 225 
LLP P     OP3    sing N N 226 
LLP N     CA     sing N N 227 
LLP CA    CB     sing N N 228 
LLP CA    C      sing N N 229 
LLP CB    CG     sing N N 230 
LLP CG    CD     sing N N 231 
LLP CD    CE     sing N N 232 
LLP CE    NZ     sing N N 233 
LLP C     O      doub N N 234 
LLP C     OXT    sing N N 235 
LLP "C2'" "H2'1" sing N N 236 
LLP "C2'" "H2'2" sing N N 237 
LLP "C2'" "H2'3" sing N N 238 
LLP O3    HO3    sing N N 239 
LLP "C4'" "H4'1" sing N N 240 
LLP C6    H6     sing N N 241 
LLP "C5'" "H5'1" sing N N 242 
LLP "C5'" "H5'2" sing N N 243 
LLP OP2   HOP2   sing N N 244 
LLP OP3   HOP3   sing N N 245 
LLP N     H      sing N N 246 
LLP N     H2     sing N N 247 
LLP CA    HA     sing N N 248 
LLP CB    HB2    sing N N 249 
LLP CB    HB3    sing N N 250 
LLP CG    HG2    sing N N 251 
LLP CG    HG3    sing N N 252 
LLP CD    HD2    sing N N 253 
LLP CD    HD3    sing N N 254 
LLP CE    HE2    sing N N 255 
LLP CE    HE3    sing N N 256 
LLP OXT   HXT    sing N N 257 
LYS N     CA     sing N N 258 
LYS N     H      sing N N 259 
LYS N     H2     sing N N 260 
LYS CA    C      sing N N 261 
LYS CA    CB     sing N N 262 
LYS CA    HA     sing N N 263 
LYS C     O      doub N N 264 
LYS C     OXT    sing N N 265 
LYS CB    CG     sing N N 266 
LYS CB    HB2    sing N N 267 
LYS CB    HB3    sing N N 268 
LYS CG    CD     sing N N 269 
LYS CG    HG2    sing N N 270 
LYS CG    HG3    sing N N 271 
LYS CD    CE     sing N N 272 
LYS CD    HD2    sing N N 273 
LYS CD    HD3    sing N N 274 
LYS CE    NZ     sing N N 275 
LYS CE    HE2    sing N N 276 
LYS CE    HE3    sing N N 277 
LYS NZ    HZ1    sing N N 278 
LYS NZ    HZ2    sing N N 279 
LYS NZ    HZ3    sing N N 280 
LYS OXT   HXT    sing N N 281 
MET N     CA     sing N N 282 
MET N     H      sing N N 283 
MET N     H2     sing N N 284 
MET CA    C      sing N N 285 
MET CA    CB     sing N N 286 
MET CA    HA     sing N N 287 
MET C     O      doub N N 288 
MET C     OXT    sing N N 289 
MET CB    CG     sing N N 290 
MET CB    HB2    sing N N 291 
MET CB    HB3    sing N N 292 
MET CG    SD     sing N N 293 
MET CG    HG2    sing N N 294 
MET CG    HG3    sing N N 295 
MET SD    CE     sing N N 296 
MET CE    HE1    sing N N 297 
MET CE    HE2    sing N N 298 
MET CE    HE3    sing N N 299 
MET OXT   HXT    sing N N 300 
PHE N     CA     sing N N 301 
PHE N     H      sing N N 302 
PHE N     H2     sing N N 303 
PHE CA    C      sing N N 304 
PHE CA    CB     sing N N 305 
PHE CA    HA     sing N N 306 
PHE C     O      doub N N 307 
PHE C     OXT    sing N N 308 
PHE CB    CG     sing N N 309 
PHE CB    HB2    sing N N 310 
PHE CB    HB3    sing N N 311 
PHE CG    CD1    doub Y N 312 
PHE CG    CD2    sing Y N 313 
PHE CD1   CE1    sing Y N 314 
PHE CD1   HD1    sing N N 315 
PHE CD2   CE2    doub Y N 316 
PHE CD2   HD2    sing N N 317 
PHE CE1   CZ     doub Y N 318 
PHE CE1   HE1    sing N N 319 
PHE CE2   CZ     sing Y N 320 
PHE CE2   HE2    sing N N 321 
PHE CZ    HZ     sing N N 322 
PHE OXT   HXT    sing N N 323 
PRO N     CA     sing N N 324 
PRO N     CD     sing N N 325 
PRO N     H      sing N N 326 
PRO CA    C      sing N N 327 
PRO CA    CB     sing N N 328 
PRO CA    HA     sing N N 329 
PRO C     O      doub N N 330 
PRO C     OXT    sing N N 331 
PRO CB    CG     sing N N 332 
PRO CB    HB2    sing N N 333 
PRO CB    HB3    sing N N 334 
PRO CG    CD     sing N N 335 
PRO CG    HG2    sing N N 336 
PRO CG    HG3    sing N N 337 
PRO CD    HD2    sing N N 338 
PRO CD    HD3    sing N N 339 
PRO OXT   HXT    sing N N 340 
SER N     CA     sing N N 341 
SER N     H      sing N N 342 
SER N     H2     sing N N 343 
SER CA    C      sing N N 344 
SER CA    CB     sing N N 345 
SER CA    HA     sing N N 346 
SER C     O      doub N N 347 
SER C     OXT    sing N N 348 
SER CB    OG     sing N N 349 
SER CB    HB2    sing N N 350 
SER CB    HB3    sing N N 351 
SER OG    HG     sing N N 352 
SER OXT   HXT    sing N N 353 
THR N     CA     sing N N 354 
THR N     H      sing N N 355 
THR N     H2     sing N N 356 
THR CA    C      sing N N 357 
THR CA    CB     sing N N 358 
THR CA    HA     sing N N 359 
THR C     O      doub N N 360 
THR C     OXT    sing N N 361 
THR CB    OG1    sing N N 362 
THR CB    CG2    sing N N 363 
THR CB    HB     sing N N 364 
THR OG1   HG1    sing N N 365 
THR CG2   HG21   sing N N 366 
THR CG2   HG22   sing N N 367 
THR CG2   HG23   sing N N 368 
THR OXT   HXT    sing N N 369 
TRP N     CA     sing N N 370 
TRP N     H      sing N N 371 
TRP N     H2     sing N N 372 
TRP CA    C      sing N N 373 
TRP CA    CB     sing N N 374 
TRP CA    HA     sing N N 375 
TRP C     O      doub N N 376 
TRP C     OXT    sing N N 377 
TRP CB    CG     sing N N 378 
TRP CB    HB2    sing N N 379 
TRP CB    HB3    sing N N 380 
TRP CG    CD1    doub Y N 381 
TRP CG    CD2    sing Y N 382 
TRP CD1   NE1    sing Y N 383 
TRP CD1   HD1    sing N N 384 
TRP CD2   CE2    doub Y N 385 
TRP CD2   CE3    sing Y N 386 
TRP NE1   CE2    sing Y N 387 
TRP NE1   HE1    sing N N 388 
TRP CE2   CZ2    sing Y N 389 
TRP CE3   CZ3    doub Y N 390 
TRP CE3   HE3    sing N N 391 
TRP CZ2   CH2    doub Y N 392 
TRP CZ2   HZ2    sing N N 393 
TRP CZ3   CH2    sing Y N 394 
TRP CZ3   HZ3    sing N N 395 
TRP CH2   HH2    sing N N 396 
TRP OXT   HXT    sing N N 397 
TYR N     CA     sing N N 398 
TYR N     H      sing N N 399 
TYR N     H2     sing N N 400 
TYR CA    C      sing N N 401 
TYR CA    CB     sing N N 402 
TYR CA    HA     sing N N 403 
TYR C     O      doub N N 404 
TYR C     OXT    sing N N 405 
TYR CB    CG     sing N N 406 
TYR CB    HB2    sing N N 407 
TYR CB    HB3    sing N N 408 
TYR CG    CD1    doub Y N 409 
TYR CG    CD2    sing Y N 410 
TYR CD1   CE1    sing Y N 411 
TYR CD1   HD1    sing N N 412 
TYR CD2   CE2    doub Y N 413 
TYR CD2   HD2    sing N N 414 
TYR CE1   CZ     doub Y N 415 
TYR CE1   HE1    sing N N 416 
TYR CE2   CZ     sing Y N 417 
TYR CE2   HE2    sing N N 418 
TYR CZ    OH     sing N N 419 
TYR OH    HH     sing N N 420 
TYR OXT   HXT    sing N N 421 
VAL N     CA     sing N N 422 
VAL N     H      sing N N 423 
VAL N     H2     sing N N 424 
VAL CA    C      sing N N 425 
VAL CA    CB     sing N N 426 
VAL CA    HA     sing N N 427 
VAL C     O      doub N N 428 
VAL C     OXT    sing N N 429 
VAL CB    CG1    sing N N 430 
VAL CB    CG2    sing N N 431 
VAL CB    HB     sing N N 432 
VAL CG1   HG11   sing N N 433 
VAL CG1   HG12   sing N N 434 
VAL CG1   HG13   sing N N 435 
VAL CG2   HG21   sing N N 436 
VAL CG2   HG22   sing N N 437 
VAL CG2   HG23   sing N N 438 
VAL OXT   HXT    sing N N 439 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2ez1 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9J3U 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.008975 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006424 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.016972 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
K 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N      . MET A 1 1   ? -12.847 -29.940 -37.939 1.00 90.78  ? 1   MET A N      1 
ATOM   2     C CA     . MET A 1 1   ? -12.775 -30.543 -36.622 1.00 61.76  ? 1   MET A CA     1 
ATOM   3     C C      . MET A 1 1   ? -14.005 -30.200 -35.806 1.00 53.50  ? 1   MET A C      1 
ATOM   4     O O      . MET A 1 1   ? -14.573 -29.144 -35.945 1.00 58.88  ? 1   MET A O      1 
ATOM   5     C CB     . MET A 1 1   ? -11.529 -30.067 -35.898 1.00 50.92  ? 1   MET A CB     1 
ATOM   6     C CG     . MET A 1 1   ? -10.347 -31.003 -35.919 1.00 70.00  ? 1   MET A CG     1 
ATOM   7     S SD     . MET A 1 1   ? -9.027  -30.353 -34.909 1.00 86.83  ? 1   MET A SD     1 
ATOM   8     C CE     . MET A 1 1   ? -9.281  -31.087 -33.333 1.00 64.08  ? 1   MET A CE     1 
ATOM   9     H H1     . MET A 1 1   ? -12.036 -29.929 -38.305 1.00 108.94 ? 1   MET A H1     1 
ATOM   10    H H2     . MET A 1 1   ? -13.398 -30.414 -38.453 1.00 108.94 ? 1   MET A H2     1 
ATOM   11    H H3     . MET A 1 1   ? -13.151 -29.107 -37.867 1.00 108.94 ? 1   MET A H3     1 
ATOM   12    H HA     . MET A 1 1   ? -12.717 -31.507 -36.718 1.00 74.12  ? 1   MET A HA     1 
ATOM   13    H HB2    . MET A 1 1   ? -11.243 -29.232 -36.301 1.00 61.10  ? 1   MET A HB2    1 
ATOM   14    H HB3    . MET A 1 1   ? -11.758 -29.913 -34.968 1.00 61.10  ? 1   MET A HB3    1 
ATOM   15    H HG2    . MET A 1 1   ? -10.611 -31.866 -35.563 1.00 84.00  ? 1   MET A HG2    1 
ATOM   16    H HG3    . MET A 1 1   ? -10.022 -31.095 -36.828 1.00 84.00  ? 1   MET A HG3    1 
ATOM   17    H HE1    . MET A 1 1   ? -8.506  -30.913 -32.776 1.00 76.89  ? 1   MET A HE1    1 
ATOM   18    H HE2    . MET A 1 1   ? -10.072 -30.698 -32.930 1.00 76.89  ? 1   MET A HE2    1 
ATOM   19    H HE3    . MET A 1 1   ? -9.399  -32.043 -33.445 1.00 76.89  ? 1   MET A HE3    1 
ATOM   20    N N      . MET A 1 2   ? -14.396 -31.118 -34.945 1.00 46.67  ? 2   MET A N      1 
ATOM   21    C CA     . MET A 1 2   ? -15.467 -30.875 -34.046 1.00 35.78  ? 2   MET A CA     1 
ATOM   22    C C      . MET A 1 2   ? -15.087 -29.789 -33.083 1.00 31.87  ? 2   MET A C      1 
ATOM   23    O O      . MET A 1 2   ? -15.850 -28.928 -32.859 1.00 29.58  ? 2   MET A O      1 
ATOM   24    C CB     . MET A 1 2   ? -15.856 -32.146 -33.297 1.00 28.14  ? 2   MET A CB     1 
ATOM   25    C CG     . MET A 1 2   ? -16.973 -32.930 -33.940 1.00 26.43  ? 2   MET A CG     1 
ATOM   26    S SD     . MET A 1 2   ? -17.681 -34.144 -32.815 1.00 76.27  ? 2   MET A SD     1 
ATOM   27    C CE     . MET A 1 2   ? -16.208 -34.827 -32.100 1.00 29.59  ? 2   MET A CE     1 
ATOM   28    H H      . MET A 1 2   ? -14.042 -31.898 -34.872 1.00 56.00  ? 2   MET A H      1 
ATOM   29    H HA     . MET A 1 2   ? -16.240 -30.583 -34.554 1.00 42.93  ? 2   MET A HA     1 
ATOM   30    H HB2    . MET A 1 2   ? -15.078 -32.722 -33.249 1.00 33.76  ? 2   MET A HB2    1 
ATOM   31    H HB3    . MET A 1 2   ? -16.142 -31.905 -32.402 1.00 33.76  ? 2   MET A HB3    1 
ATOM   32    H HG2    . MET A 1 2   ? -17.678 -32.320 -34.208 1.00 31.72  ? 2   MET A HG2    1 
ATOM   33    H HG3    . MET A 1 2   ? -16.627 -33.401 -34.714 1.00 31.72  ? 2   MET A HG3    1 
ATOM   34    H HE1    . MET A 1 2   ? -16.438 -35.639 -31.621 1.00 35.51  ? 2   MET A HE1    1 
ATOM   35    H HE2    . MET A 1 2   ? -15.578 -35.029 -32.809 1.00 35.51  ? 2   MET A HE2    1 
ATOM   36    H HE3    . MET A 1 2   ? -15.822 -34.180 -31.489 1.00 35.51  ? 2   MET A HE3    1 
ATOM   37    N N      . TYR A 1 3   ? -13.889 -29.841 -32.537 1.00 27.07  ? 3   TYR A N      1 
ATOM   38    C CA     . TYR A 1 3   ? -13.472 -28.843 -31.591 1.00 23.87  ? 3   TYR A CA     1 
ATOM   39    C C      . TYR A 1 3   ? -12.072 -28.353 -31.908 1.00 25.48  ? 3   TYR A C      1 
ATOM   40    O O      . TYR A 1 3   ? -11.130 -28.893 -31.430 1.00 27.24  ? 3   TYR A O      1 
ATOM   41    C CB     . TYR A 1 3   ? -13.660 -29.350 -30.171 1.00 20.78  ? 3   TYR A CB     1 
ATOM   42    C CG     . TYR A 1 3   ? -15.075 -29.792 -29.900 1.00 24.35  ? 3   TYR A CG     1 
ATOM   43    C CD1    . TYR A 1 3   ? -16.111 -28.900 -29.943 1.00 23.75  ? 3   TYR A CD1    1 
ATOM   44    C CD2    . TYR A 1 3   ? -15.381 -31.093 -29.620 1.00 24.50  ? 3   TYR A CD2    1 
ATOM   45    C CE1    . TYR A 1 3   ? -17.385 -29.290 -29.700 1.00 22.43  ? 3   TYR A CE1    1 
ATOM   46    C CE2    . TYR A 1 3   ? -16.659 -31.477 -29.399 1.00 26.42  ? 3   TYR A CE2    1 
ATOM   47    C CZ     . TYR A 1 3   ? -17.655 -30.559 -29.449 1.00 26.79  ? 3   TYR A CZ     1 
ATOM   48    O OH     . TYR A 1 3   ? -18.922 -30.895 -29.233 1.00 34.04  ? 3   TYR A OH     1 
ATOM   49    H H      . TYR A 1 3   ? -13.300 -30.446 -32.700 1.00 32.48  ? 3   TYR A H      1 
ATOM   50    H HA     . TYR A 1 3   ? -14.059 -28.079 -31.660 1.00 28.64  ? 3   TYR A HA     1 
ATOM   51    H HB2    . TYR A 1 3   ? -13.074 -30.110 -30.025 1.00 24.94  ? 3   TYR A HB2    1 
ATOM   52    H HB3    . TYR A 1 3   ? -13.443 -28.638 -29.549 1.00 24.94  ? 3   TYR A HB3    1 
ATOM   53    H HD1    . TYR A 1 3   ? -15.935 -28.006 -30.127 1.00 28.50  ? 3   TYR A HD1    1 
ATOM   54    H HD2    . TYR A 1 3   ? -14.702 -31.727 -29.594 1.00 29.40  ? 3   TYR A HD2    1 
ATOM   55    H HE1    . TYR A 1 3   ? -18.076 -28.668 -29.740 1.00 26.91  ? 3   TYR A HE1    1 
ATOM   56    H HE2    . TYR A 1 3   ? -16.853 -32.367 -29.211 1.00 31.71  ? 3   TYR A HE2    1 
ATOM   57    H HH     . TYR A 1 3   ? -18.979 -31.720 -29.085 1.00 40.85  ? 3   TYR A HH     1 
ATOM   58    N N      . PRO A 1 4   ? -11.969 -27.332 -32.742 1.00 21.04  ? 4   PRO A N      1 
ATOM   59    C CA     . PRO A 1 4   ? -10.648 -26.868 -33.170 1.00 22.02  ? 4   PRO A CA     1 
ATOM   60    C C      . PRO A 1 4   ? -9.889  -26.124 -32.073 1.00 19.13  ? 4   PRO A C      1 
ATOM   61    O O      . PRO A 1 4   ? -10.507 -25.570 -31.158 1.00 16.66  ? 4   PRO A O      1 
ATOM   62    C CB     . PRO A 1 4   ? -10.974 -25.925 -34.328 1.00 23.98  ? 4   PRO A CB     1 
ATOM   63    C CG     . PRO A 1 4   ? -12.313 -25.375 -33.981 1.00 22.20  ? 4   PRO A CG     1 
ATOM   64    C CD     . PRO A 1 4   ? -13.049 -26.525 -33.340 1.00 22.31  ? 4   PRO A CD     1 
ATOM   65    H HA     . PRO A 1 4   ? -10.113 -27.609 -33.494 1.00 26.42  ? 4   PRO A HA     1 
ATOM   66    H HB2    . PRO A 1 4   ? -10.311 -25.218 -34.375 1.00 28.78  ? 4   PRO A HB2    1 
ATOM   67    H HB3    . PRO A 1 4   ? -11.009 -26.423 -35.159 1.00 28.78  ? 4   PRO A HB3    1 
ATOM   68    H HG2    . PRO A 1 4   ? -12.213 -24.640 -33.356 1.00 26.63  ? 4   PRO A HG2    1 
ATOM   69    H HG3    . PRO A 1 4   ? -12.766 -25.083 -34.787 1.00 26.63  ? 4   PRO A HG3    1 
ATOM   70    H HD2    . PRO A 1 4   ? -13.648 -26.193 -32.653 1.00 26.77  ? 4   PRO A HD2    1 
ATOM   71    H HD3    . PRO A 1 4   ? -13.525 -27.039 -34.011 1.00 26.77  ? 4   PRO A HD3    1 
ATOM   72    N N      . ALA A 1 5   ? -8.564  -26.101 -32.185 1.00 17.64  ? 5   ALA A N      1 
ATOM   73    C CA     . ALA A 1 5   ? -7.723  -25.357 -31.250 1.00 18.81  ? 5   ALA A CA     1 
ATOM   74    C C      . ALA A 1 5   ? -7.913  -23.861 -31.487 1.00 16.66  ? 5   ALA A C      1 
ATOM   75    O O      . ALA A 1 5   ? -8.403  -23.442 -32.540 1.00 18.80  ? 5   ALA A O      1 
ATOM   76    C CB     . ALA A 1 5   ? -6.253  -25.749 -31.410 1.00 17.22  ? 5   ALA A CB     1 
ATOM   77    H H      . ALA A 1 5   ? -8.124  -26.512 -32.799 1.00 21.17  ? 5   ALA A H      1 
ATOM   78    H HA     . ALA A 1 5   ? -7.996  -25.559 -30.341 1.00 22.57  ? 5   ALA A HA     1 
ATOM   79    H HB1    . ALA A 1 5   ? -5.721  -25.241 -30.778 1.00 20.67  ? 5   ALA A HB1    1 
ATOM   80    H HB2    . ALA A 1 5   ? -6.159  -26.698 -31.234 1.00 20.67  ? 5   ALA A HB2    1 
ATOM   81    H HB3    . ALA A 1 5   ? -5.971  -25.551 -32.317 1.00 20.67  ? 5   ALA A HB3    1 
ATOM   82    N N      . GLU A 1 6   ? -7.539  -23.062 -30.500 1.00 16.50  ? 6   GLU A N      1 
ATOM   83    C CA     . GLU A 1 6   ? -7.639  -21.618 -30.624 1.00 16.57  ? 6   GLU A CA     1 
ATOM   84    C C      . GLU A 1 6   ? -6.826  -21.134 -31.825 1.00 16.04  ? 6   GLU A C      1 
ATOM   85    O O      . GLU A 1 6   ? -5.650  -21.458 -31.938 1.00 18.94  ? 6   GLU A O      1 
ATOM   86    C CB     . GLU A 1 6   ? -7.145  -20.927 -29.358 1.00 19.90  ? 6   GLU A CB     1 
ATOM   87    C CG     . GLU A 1 6   ? -7.951  -21.244 -28.120 1.00 18.47  ? 6   GLU A CG     1 
ATOM   88    C CD     . GLU A 1 6   ? -7.559  -22.552 -27.427 1.00 23.67  ? 6   GLU A CD     1 
ATOM   89    O OE1    . GLU A 1 6   ? -6.577  -23.202 -27.853 1.00 21.55  ? 6   GLU A OE1    1 
ATOM   90    O OE2    . GLU A 1 6   ? -8.247  -22.929 -26.446 1.00 25.79  ? 6   GLU A OE2    1 
ATOM   91    H H      . GLU A 1 6   ? -7.219  -23.333 -29.751 1.00 19.80  ? 6   GLU A H      1 
ATOM   92    H HA     . GLU A 1 6   ? -8.572  -21.388 -30.737 1.00 19.88  ? 6   GLU A HA     1 
ATOM   93    H HB2    . GLU A 1 6   ? -6.225  -21.187 -29.197 1.00 23.88  ? 6   GLU A HB2    1 
ATOM   94    H HB3    . GLU A 1 6   ? -7.190  -19.968 -29.496 1.00 23.88  ? 6   GLU A HB3    1 
ATOM   95    H HG2    . GLU A 1 6   ? -7.833  -20.525 -27.480 1.00 22.16  ? 6   GLU A HG2    1 
ATOM   96    H HG3    . GLU A 1 6   ? -8.887  -21.311 -28.367 1.00 22.16  ? 6   GLU A HG3    1 
ATOM   97    N N      . PRO A 1 7   ? -7.451  -20.347 -32.717 1.00 17.14  ? 7   PRO A N      1 
ATOM   98    C CA     . PRO A 1 7   ? -6.751  -19.802 -33.886 1.00 18.22  ? 7   PRO A CA     1 
ATOM   99    C C      . PRO A 1 7   ? -6.009  -18.502 -33.569 1.00 17.31  ? 7   PRO A C      1 
ATOM   100   O O      . PRO A 1 7   ? -6.076  -17.516 -34.313 1.00 16.92  ? 7   PRO A O      1 
ATOM   101   C CB     . PRO A 1 7   ? -7.892  -19.565 -34.877 1.00 21.25  ? 7   PRO A CB     1 
ATOM   102   C CG     . PRO A 1 7   ? -9.025  -19.163 -33.993 1.00 16.15  ? 7   PRO A CG     1 
ATOM   103   C CD     . PRO A 1 7   ? -8.887  -20.009 -32.748 1.00 17.90  ? 7   PRO A CD     1 
ATOM   104   H HA     . PRO A 1 7   ? -6.132  -20.453 -34.252 1.00 21.87  ? 7   PRO A HA     1 
ATOM   105   H HB2    . PRO A 1 7   ? -7.667  -18.861 -35.504 1.00 25.50  ? 7   PRO A HB2    1 
ATOM   106   H HB3    . PRO A 1 7   ? -8.097  -20.390 -35.344 1.00 25.50  ? 7   PRO A HB3    1 
ATOM   107   H HG2    . PRO A 1 7   ? -8.950  -18.221 -33.776 1.00 19.38  ? 7   PRO A HG2    1 
ATOM   108   H HG3    . PRO A 1 7   ? -9.865  -19.345 -34.437 1.00 19.38  ? 7   PRO A HG3    1 
ATOM   109   H HD2    . PRO A 1 7   ? -9.131  -19.495 -31.962 1.00 21.48  ? 7   PRO A HD2    1 
ATOM   110   H HD3    . PRO A 1 7   ? -9.422  -20.814 -32.827 1.00 21.48  ? 7   PRO A HD3    1 
ATOM   111   N N      . TYR A 1 8   ? -5.306  -18.520 -32.448 1.00 15.55  ? 8   TYR A N      1 
ATOM   112   C CA     . TYR A 1 8   ? -4.523  -17.388 -31.972 1.00 14.22  ? 8   TYR A CA     1 
ATOM   113   C C      . TYR A 1 8   ? -3.661  -17.899 -30.825 1.00 16.75  ? 8   TYR A C      1 
ATOM   114   O O      . TYR A 1 8   ? -3.840  -19.037 -30.367 1.00 15.51  ? 8   TYR A O      1 
ATOM   115   C CB     . TYR A 1 8   ? -5.413  -16.225 -31.507 1.00 15.22  ? 8   TYR A CB     1 
ATOM   116   C CG     . TYR A 1 8   ? -6.571  -16.649 -30.631 1.00 15.83  ? 8   TYR A CG     1 
ATOM   117   C CD1    . TYR A 1 8   ? -6.391  -16.958 -29.281 1.00 14.64  ? 8   TYR A CD1    1 
ATOM   118   C CD2    . TYR A 1 8   ? -7.848  -16.745 -31.163 1.00 18.43  ? 8   TYR A CD2    1 
ATOM   119   C CE1    . TYR A 1 8   ? -7.472  -17.351 -28.491 1.00 20.16  ? 8   TYR A CE1    1 
ATOM   120   C CE2    . TYR A 1 8   ? -8.916  -17.140 -30.393 1.00 18.89  ? 8   TYR A CE2    1 
ATOM   121   C CZ     . TYR A 1 8   ? -8.729  -17.433 -29.067 1.00 18.03  ? 8   TYR A CZ     1 
ATOM   122   O OH     . TYR A 1 8   ? -9.821  -17.817 -28.326 1.00 26.38  ? 8   TYR A OH     1 
ATOM   123   H H      . TYR A 1 8   ? -5.261  -19.201 -31.926 1.00 18.66  ? 8   TYR A H      1 
ATOM   124   H HA     . TYR A 1 8   ? -3.942  -17.071 -32.681 1.00 17.07  ? 8   TYR A HA     1 
ATOM   125   H HB2    . TYR A 1 8   ? -4.871  -15.601 -30.999 1.00 18.27  ? 8   TYR A HB2    1 
ATOM   126   H HB3    . TYR A 1 8   ? -5.780  -15.781 -32.288 1.00 18.27  ? 8   TYR A HB3    1 
ATOM   127   H HD1    . TYR A 1 8   ? -5.543  -16.899 -28.904 1.00 17.56  ? 8   TYR A HD1    1 
ATOM   128   H HD2    . TYR A 1 8   ? -7.983  -16.547 -32.062 1.00 22.12  ? 8   TYR A HD2    1 
ATOM   129   H HE1    . TYR A 1 8   ? -7.350  -17.555 -27.592 1.00 24.20  ? 8   TYR A HE1    1 
ATOM   130   H HE2    . TYR A 1 8   ? -9.766  -17.195 -30.767 1.00 22.67  ? 8   TYR A HE2    1 
ATOM   131   H HH     . TYR A 1 8   ? -9.592  -17.961 -27.531 1.00 31.66  ? 8   TYR A HH     1 
ATOM   132   N N      . ARG A 1 9   ? -2.720  -17.068 -30.389 1.00 13.09  ? 9   ARG A N      1 
ATOM   133   C CA     . ARG A 1 9   ? -1.923  -17.334 -29.193 1.00 16.15  ? 9   ARG A CA     1 
ATOM   134   C C      . ARG A 1 9   ? -2.312  -16.376 -28.098 1.00 17.22  ? 9   ARG A C      1 
ATOM   135   O O      . ARG A 1 9   ? -2.903  -15.327 -28.356 1.00 18.31  ? 9   ARG A O      1 
ATOM   136   C CB     . ARG A 1 9   ? -0.427  -17.169 -29.450 1.00 14.18  ? 9   ARG A CB     1 
ATOM   137   C CG     . ARG A 1 9   ? 0.034   -17.557 -30.825 1.00 17.36  ? 9   ARG A CG     1 
ATOM   138   C CD     . ARG A 1 9   ? 1.534   -17.424 -30.914 1.00 20.40  ? 9   ARG A CD     1 
ATOM   139   N NE     . ARG A 1 9   ? 2.036   -17.884 -32.199 1.00 19.05  ? 9   ARG A NE     1 
ATOM   140   C CZ     . ARG A 1 9   ? 3.250   -17.618 -32.663 1.00 23.96  ? 9   ARG A CZ     1 
ATOM   141   N NH1    . ARG A 1 9   ? 4.090   -16.879 -31.942 1.00 20.72  ? 9   ARG A NH1    1 
ATOM   142   N NH2    . ARG A 1 9   ? 3.624   -18.083 -33.848 1.00 22.12  ? 9   ARG A NH2    1 
ATOM   143   H H      . ARG A 1 9   ? -2.519  -16.327 -30.777 1.00 15.71  ? 9   ARG A H      1 
ATOM   144   H HA     . ARG A 1 9   ? -2.081  -18.238 -28.880 1.00 19.37  ? 9   ARG A HA     1 
ATOM   145   H HB2    . ARG A 1 9   ? -0.193  -16.237 -29.316 1.00 17.02  ? 9   ARG A HB2    1 
ATOM   146   H HB3    . ARG A 1 9   ? 0.057   -17.719 -28.814 1.00 17.02  ? 9   ARG A HB3    1 
ATOM   147   H HG2    . ARG A 1 9   ? -0.206  -18.480 -31.001 1.00 20.83  ? 9   ARG A HG2    1 
ATOM   148   H HG3    . ARG A 1 9   ? -0.367  -16.968 -31.483 1.00 20.83  ? 9   ARG A HG3    1 
ATOM   149   H HD2    . ARG A 1 9   ? 1.776   -16.491 -30.808 1.00 24.48  ? 9   ARG A HD2    1 
ATOM   150   H HD3    . ARG A 1 9   ? 1.945   -17.959 -30.217 1.00 24.48  ? 9   ARG A HD3    1 
ATOM   151   H HE     . ARG A 1 9   ? 1.502   -18.333 -32.702 1.00 22.86  ? 9   ARG A HE     1 
ATOM   152   H HH11   . ARG A 1 9   ? 3.853   -16.576 -31.173 1.00 24.86  ? 9   ARG A HH11   1 
ATOM   153   H HH12   . ARG A 1 9   ? 4.876   -16.707 -32.245 1.00 24.86  ? 9   ARG A HH12   1 
ATOM   154   H HH21   . ARG A 1 9   ? 3.080   -18.559 -34.314 1.00 26.54  ? 9   ARG A HH21   1 
ATOM   155   H HH22   . ARG A 1 9   ? 4.410   -17.908 -34.150 1.00 26.54  ? 9   ARG A HH22   1 
ATOM   156   N N      . ILE A 1 10  ? -1.928  -16.710 -26.873 1.00 15.05  ? 10  ILE A N      1 
ATOM   157   C CA     . ILE A 1 10  ? -2.090  -15.779 -25.770 1.00 15.07  ? 10  ILE A CA     1 
ATOM   158   C C      . ILE A 1 10  ? -0.962  -14.751 -25.832 1.00 15.53  ? 10  ILE A C      1 
ATOM   159   O O      . ILE A 1 10  ? 0.214   -15.116 -25.847 1.00 16.26  ? 10  ILE A O      1 
ATOM   160   C CB     . ILE A 1 10  ? -2.089  -16.505 -24.428 1.00 16.03  ? 10  ILE A CB     1 
ATOM   161   C CG1    . ILE A 1 10  ? -3.247  -17.500 -24.397 1.00 16.67  ? 10  ILE A CG1    1 
ATOM   162   C CG2    . ILE A 1 10  ? -2.189  -15.513 -23.273 1.00 18.04  ? 10  ILE A CG2    1 
ATOM   163   C CD1    . ILE A 1 10  ? -3.240  -18.408 -23.157 1.00 22.20  ? 10  ILE A CD1    1 
ATOM   164   H H      . ILE A 1 10  ? -1.574  -17.463 -26.657 1.00 18.06  ? 10  ILE A H      1 
ATOM   165   H HA     . ILE A 1 10  ? -2.935  -15.312 -25.859 1.00 18.09  ? 10  ILE A HA     1 
ATOM   166   H HB     . ILE A 1 10  ? -1.258  -16.996 -24.343 1.00 19.24  ? 10  ILE A HB     1 
ATOM   167   H HG12   . ILE A 1 10  ? -4.082  -17.009 -24.408 1.00 20.00  ? 10  ILE A HG12   1 
ATOM   168   H HG13   . ILE A 1 10  ? -3.193  -18.072 -25.178 1.00 20.00  ? 10  ILE A HG13   1 
ATOM   169   H HG21   . ILE A 1 10  ? -2.305  -16.000 -22.443 1.00 21.65  ? 10  ILE A HG21   1 
ATOM   170   H HG22   . ILE A 1 10  ? -1.375  -14.988 -23.230 1.00 21.65  ? 10  ILE A HG22   1 
ATOM   171   H HG23   . ILE A 1 10  ? -2.951  -14.931 -23.423 1.00 21.65  ? 10  ILE A HG23   1 
ATOM   172   H HD11   . ILE A 1 10  ? -3.866  -19.136 -23.296 1.00 26.65  ? 10  ILE A HD11   1 
ATOM   173   H HD12   . ILE A 1 10  ? -2.345  -18.761 -23.030 1.00 26.65  ? 10  ILE A HD12   1 
ATOM   174   H HD13   . ILE A 1 10  ? -3.503  -17.889 -22.382 1.00 26.65  ? 10  ILE A HD13   1 
ATOM   175   N N      . LYS A 1 11  ? -1.328  -13.472 -25.916 1.00 15.80  ? 11  LYS A N      1 
ATOM   176   C CA     . LYS A 1 11  ? -0.350  -12.383 -25.865 1.00 15.58  ? 11  LYS A CA     1 
ATOM   177   C C      . LYS A 1 11  ? -0.110  -11.910 -24.439 1.00 13.89  ? 11  LYS A C      1 
ATOM   178   O O      . LYS A 1 11  ? 1.034   -11.695 -24.030 1.00 15.01  ? 11  LYS A O      1 
ATOM   179   C CB     . LYS A 1 11  ? -0.806  -11.204 -26.720 1.00 15.77  ? 11  LYS A CB     1 
ATOM   180   C CG     . LYS A 1 11  ? 0.183   -10.034 -26.737 1.00 18.62  ? 11  LYS A CG     1 
ATOM   181   C CD     . LYS A 1 11  ? 1.547   -10.463 -27.274 1.00 17.57  ? 11  LYS A CD     1 
ATOM   182   C CE     . LYS A 1 11  ? 2.563   -9.334  -27.232 1.00 23.72  ? 11  LYS A CE     1 
ATOM   183   N NZ     . LYS A 1 11  ? 2.179   -8.214  -28.141 1.00 23.94  ? 11  LYS A NZ     1 
ATOM   184   H H      . LYS A 1 11  ? -2.141  -13.206 -26.003 1.00 18.96  ? 11  LYS A H      1 
ATOM   185   H HA     . LYS A 1 11  ? 0.492   -12.706 -26.220 1.00 18.70  ? 11  LYS A HA     1 
ATOM   186   H HB2    . LYS A 1 11  ? -0.922  -11.507 -27.634 1.00 18.93  ? 11  LYS A HB2    1 
ATOM   187   H HB3    . LYS A 1 11  ? -1.650  -10.875 -26.374 1.00 18.93  ? 11  LYS A HB3    1 
ATOM   188   H HG2    . LYS A 1 11  ? -0.162  -9.336  -27.315 1.00 22.34  ? 11  LYS A HG2    1 
ATOM   189   H HG3    . LYS A 1 11  ? 0.302   -9.692  -25.837 1.00 22.34  ? 11  LYS A HG3    1 
ATOM   190   H HD2    . LYS A 1 11  ? 1.897   -11.187 -26.733 1.00 21.09  ? 11  LYS A HD2    1 
ATOM   191   H HD3    . LYS A 1 11  ? 1.451   -10.750 -28.196 1.00 21.09  ? 11  LYS A HD3    1 
ATOM   192   H HE2    . LYS A 1 11  ? 2.617   -8.986  -26.328 1.00 28.47  ? 11  LYS A HE2    1 
ATOM   193   H HE3    . LYS A 1 11  ? 3.428   -9.671  -27.514 1.00 28.47  ? 11  LYS A HE3    1 
ATOM   194   H HZ1    . LYS A 1 11  ? 2.122   -8.509  -28.979 1.00 28.72  ? 11  LYS A HZ1    1 
ATOM   195   H HZ2    . LYS A 1 11  ? 1.391   -7.881  -27.897 1.00 28.72  ? 11  LYS A HZ2    1 
ATOM   196   H HZ3    . LYS A 1 11  ? 2.790   -7.568  -28.103 1.00 28.72  ? 11  LYS A HZ3    1 
ATOM   197   N N      . SER A 1 12  ? -1.192  -11.720 -23.687 1.00 15.22  ? 12  SER A N      1 
ATOM   198   C CA     . SER A 1 12  ? -1.074  -11.385 -22.274 1.00 13.67  ? 12  SER A CA     1 
ATOM   199   C C      . SER A 1 12  ? -2.196  -12.035 -21.488 1.00 15.02  ? 12  SER A C      1 
ATOM   200   O O      . SER A 1 12  ? -3.259  -12.357 -22.041 1.00 12.98  ? 12  SER A O      1 
ATOM   201   C CB     . SER A 1 12  ? -1.090  -9.869  -22.060 1.00 13.80  ? 12  SER A CB     1 
ATOM   202   O OG     . SER A 1 12  ? -2.366  -9.326  -22.332 1.00 14.89  ? 12  SER A OG     1 
ATOM   203   H H      . SER A 1 12  ? -2.002  -11.779 -23.971 1.00 18.27  ? 12  SER A H      1 
ATOM   204   H HA     . SER A 1 12  ? -0.237  -11.735 -21.942 1.00 16.41  ? 12  SER A HA     1 
ATOM   205   H HB2    . SER A 1 12  ? -0.858  -9.679  -21.138 1.00 16.56  ? 12  SER A HB2    1 
ATOM   206   H HB3    . SER A 1 12  ? -0.441  -9.461  -22.655 1.00 16.56  ? 12  SER A HB3    1 
ATOM   207   H HG     . SER A 1 12  ? -2.357  -8.495  -22.210 1.00 17.87  ? 12  SER A HG     1 
ATOM   208   N N      . VAL A 1 13  ? -1.952  -12.223 -20.194 1.00 15.98  ? 13  VAL A N      1 
ATOM   209   C CA     . VAL A 1 13  ? -2.895  -12.904 -19.328 1.00 14.25  ? 13  VAL A CA     1 
ATOM   210   C C      . VAL A 1 13  ? -3.462  -11.965 -18.280 1.00 15.58  ? 13  VAL A C      1 
ATOM   211   O O      . VAL A 1 13  ? -2.840  -10.965 -17.891 1.00 16.89  ? 13  VAL A O      1 
ATOM   212   C CB     . VAL A 1 13  ? -2.258  -14.108 -18.627 1.00 17.33  ? 13  VAL A CB     1 
ATOM   213   C CG1    . VAL A 1 13  ? -1.786  -15.135 -19.667 1.00 15.44  ? 13  VAL A CG1    1 
ATOM   214   C CG2    . VAL A 1 13  ? -1.116  -13.674 -17.724 1.00 16.93  ? 13  VAL A CG2    1 
ATOM   215   H H      . VAL A 1 13  ? -1.238  -11.959 -19.794 1.00 19.18  ? 13  VAL A H      1 
ATOM   216   H HA     . VAL A 1 13  ? -3.638  -13.236 -19.854 1.00 17.10  ? 13  VAL A HA     1 
ATOM   217   H HB     . VAL A 1 13  ? -2.928  -14.536 -18.071 1.00 20.80  ? 13  VAL A HB     1 
ATOM   218   H HG11   . VAL A 1 13  ? -1.404  -15.898 -19.206 1.00 18.52  ? 13  VAL A HG11   1 
ATOM   219   H HG12   . VAL A 1 13  ? -2.547  -15.417 -20.199 1.00 18.52  ? 13  VAL A HG12   1 
ATOM   220   H HG13   . VAL A 1 13  ? -1.118  -14.724 -20.237 1.00 18.52  ? 13  VAL A HG13   1 
ATOM   221   H HG21   . VAL A 1 13  ? -0.682  -14.465 -17.367 1.00 20.31  ? 13  VAL A HG21   1 
ATOM   222   H HG22   . VAL A 1 13  ? -0.480  -13.158 -18.243 1.00 20.31  ? 13  VAL A HG22   1 
ATOM   223   H HG23   . VAL A 1 13  ? -1.466  -13.136 -16.997 1.00 20.31  ? 13  VAL A HG23   1 
ATOM   224   N N      . GLU A 1 14  ? -4.664  -12.291 -17.835 1.00 16.31  ? 14  GLU A N      1 
ATOM   225   C CA     . GLU A 1 14  ? -5.316  -11.528 -16.791 1.00 18.31  ? 14  GLU A CA     1 
ATOM   226   C C      . GLU A 1 14  ? -5.208  -12.291 -15.484 1.00 23.29  ? 14  GLU A C      1 
ATOM   227   O O      . GLU A 1 14  ? -5.623  -13.449 -15.380 1.00 16.96  ? 14  GLU A O      1 
ATOM   228   C CB     . GLU A 1 14  ? -6.774  -11.252 -17.144 1.00 20.42  ? 14  GLU A CB     1 
ATOM   229   C CG     . GLU A 1 14  ? -7.484  -10.396 -16.124 1.00 23.82  ? 14  GLU A CG     1 
ATOM   230   C CD     . GLU A 1 14  ? -8.914  -10.082 -16.520 1.00 32.68  ? 14  GLU A CD     1 
ATOM   231   O OE1    . GLU A 1 14  ? -9.348  -10.532 -17.605 1.00 37.87  ? 14  GLU A OE1    1 
ATOM   232   O OE2    . GLU A 1 14  ? -9.606  -9.393  -15.744 1.00 37.14  ? 14  GLU A OE2    1 
ATOM   233   H H      . GLU A 1 14  ? -5.126  -12.956 -18.125 1.00 19.57  ? 14  GLU A H      1 
ATOM   234   H HA     . GLU A 1 14  ? -4.874  -10.673 -16.677 1.00 21.98  ? 14  GLU A HA     1 
ATOM   235   H HB2    . GLU A 1 14  ? -6.808  -10.791 -17.997 1.00 24.50  ? 14  GLU A HB2    1 
ATOM   236   H HB3    . GLU A 1 14  ? -7.247  -12.096 -17.206 1.00 24.50  ? 14  GLU A HB3    1 
ATOM   237   H HG2    . GLU A 1 14  ? -7.506  -10.864 -15.275 1.00 28.58  ? 14  GLU A HG2    1 
ATOM   238   H HG3    . GLU A 1 14  ? -7.007  -9.557  -16.029 1.00 28.58  ? 14  GLU A HG3    1 
ATOM   239   N N      . THR A 1 15  ? -4.625  -11.624 -14.496 1.00 21.97  ? 15  THR A N      1 
ATOM   240   C CA     . THR A 1 15  ? -4.424  -12.200 -13.172 1.00 28.09  ? 15  THR A CA     1 
ATOM   241   C C      . THR A 1 15  ? -5.748  -12.510 -12.506 1.00 18.03  ? 15  THR A C      1 
ATOM   242   O O      . THR A 1 15  ? -6.692  -11.721 -12.583 1.00 31.38  ? 15  THR A O      1 
ATOM   243   C CB     . THR A 1 15  ? -3.628  -11.236 -12.255 1.00 29.96  ? 15  THR A CB     1 
ATOM   244   O OG1    . THR A 1 15  ? -2.446  -10.805 -12.927 1.00 26.78  ? 15  THR A OG1    1 
ATOM   245   C CG2    . THR A 1 15  ? -3.233  -11.917 -10.967 1.00 34.55  ? 15  THR A CG2    1 
ATOM   246   H H      . THR A 1 15  ? -4.331  -10.819 -14.569 1.00 26.36  ? 15  THR A H      1 
ATOM   247   H HA     . THR A 1 15  ? -3.922  -13.025 -13.256 1.00 33.71  ? 15  THR A HA     1 
ATOM   248   H HB     . THR A 1 15  ? -4.177  -10.466 -12.040 1.00 35.95  ? 15  THR A HB     1 
ATOM   249   H HG1    . THR A 1 15  ? -2.010  -10.282 -12.435 1.00 32.14  ? 15  THR A HG1    1 
ATOM   250   H HG21   . THR A 1 15  ? -2.642  -11.341 -10.457 1.00 41.46  ? 15  THR A HG21   1 
ATOM   251   H HG22   . THR A 1 15  ? -4.021  -12.108 -10.435 1.00 41.46  ? 15  THR A HG22   1 
ATOM   252   H HG23   . THR A 1 15  ? -2.772  -12.748 -11.160 1.00 41.46  ? 15  THR A HG23   1 
ATOM   253   N N      . VAL A 1 16  ? -5.818  -13.666 -11.866 1.00 24.46  ? 16  VAL A N      1 
ATOM   254   C CA     . VAL A 1 16  ? -6.941  -13.986 -10.993 1.00 27.70  ? 16  VAL A CA     1 
ATOM   255   C C      . VAL A 1 16  ? -6.386  -14.496 -9.668  1.00 28.81  ? 16  VAL A C      1 
ATOM   256   O O      . VAL A 1 16  ? -5.268  -15.005 -9.608  1.00 26.76  ? 16  VAL A O      1 
ATOM   257   C CB     . VAL A 1 16  ? -7.887  -15.062 -11.596 1.00 29.76  ? 16  VAL A CB     1 
ATOM   258   C CG1    . VAL A 1 16  ? -8.383  -14.648 -12.967 1.00 27.86  ? 16  VAL A CG1    1 
ATOM   259   C CG2    . VAL A 1 16  ? -7.183  -16.392 -11.682 1.00 25.58  ? 16  VAL A CG2    1 
ATOM   260   H H      . VAL A 1 16  ? -5.226  -14.287 -11.919 1.00 29.35  ? 16  VAL A H      1 
ATOM   261   H HA     . VAL A 1 16  ? -7.462  -13.188 -10.814 1.00 33.23  ? 16  VAL A HA     1 
ATOM   262   H HB     . VAL A 1 16  ? -8.658  -15.167 -11.016 1.00 35.72  ? 16  VAL A HB     1 
ATOM   263   H HG11   . VAL A 1 16  ? -9.007  -15.316 -13.292 1.00 33.44  ? 16  VAL A HG11   1 
ATOM   264   H HG12   . VAL A 1 16  ? -8.826  -13.788 -12.895 1.00 33.44  ? 16  VAL A HG12   1 
ATOM   265   H HG13   . VAL A 1 16  ? -7.626  -14.581 -13.570 1.00 33.44  ? 16  VAL A HG13   1 
ATOM   266   H HG21   . VAL A 1 16  ? -7.663  -16.963 -12.302 1.00 30.69  ? 16  VAL A HG21   1 
ATOM   267   H HG22   . VAL A 1 16  ? -6.277  -16.250 -11.998 1.00 30.69  ? 16  VAL A HG22   1 
ATOM   268   H HG23   . VAL A 1 16  ? -7.166  -16.801 -10.803 1.00 30.69  ? 16  VAL A HG23   1 
ATOM   269   N N      . SER A 1 17  ? -7.180  -14.375 -8.613  1.00 29.94  ? 17  SER A N      1 
ATOM   270   C CA     . SER A 1 17  ? -6.802  -14.945 -7.325  1.00 34.24  ? 17  SER A CA     1 
ATOM   271   C C      . SER A 1 17  ? -7.366  -16.367 -7.240  1.00 31.71  ? 17  SER A C      1 
ATOM   272   O O      . SER A 1 17  ? -8.557  -16.586 -7.447  1.00 31.67  ? 17  SER A O      1 
ATOM   273   C CB     . SER A 1 17  ? -7.313  -14.071 -6.182  1.00 40.85  ? 17  SER A CB     1 
ATOM   274   O OG     . SER A 1 17  ? -8.714  -13.890 -6.287  1.00 47.14  ? 17  SER A OG     1 
ATOM   275   H H      . SER A 1 17  ? -7.939  -13.971 -8.615  1.00 35.93  ? 17  SER A H      1 
ATOM   276   H HA     . SER A 1 17  ? -5.836  -14.994 -7.254  1.00 41.09  ? 17  SER A HA     1 
ATOM   277   H HB2    . SER A 1 17  ? -7.111  -14.504 -5.337  1.00 49.02  ? 17  SER A HB2    1 
ATOM   278   H HB3    . SER A 1 17  ? -6.877  -13.205 -6.225  1.00 49.02  ? 17  SER A HB3    1 
ATOM   279   H HG     . SER A 1 17  ? -8.899  -13.472 -6.992  1.00 56.57  ? 17  SER A HG     1 
ATOM   280   N N      . MET A 1 18  ? -6.507  -17.340 -6.977  1.00 37.62  ? 18  MET A N      1 
ATOM   281   C CA     . MET A 1 18  ? -6.954  -18.729 -6.971  1.00 41.72  ? 18  MET A CA     1 
ATOM   282   C C      . MET A 1 18  ? -7.387  -19.086 -5.551  1.00 34.54  ? 18  MET A C      1 
ATOM   283   O O      . MET A 1 18  ? -6.705  -19.842 -4.859  1.00 48.61  ? 18  MET A O      1 
ATOM   284   C CB     . MET A 1 18  ? -5.845  -19.666 -7.470  1.00 37.80  ? 18  MET A CB     1 
ATOM   285   C CG     . MET A 1 18  ? -5.467  -19.471 -8.937  1.00 33.30  ? 18  MET A CG     1 
ATOM   286   S SD     . MET A 1 18  ? -6.773  -19.952 -10.095 1.00 30.85  ? 18  MET A SD     1 
ATOM   287   C CE     . MET A 1 18  ? -6.647  -21.743 -10.034 1.00 27.63  ? 18  MET A CE     1 
ATOM   288   H H      . MET A 1 18  ? -5.673  -17.229 -6.801  1.00 45.14  ? 18  MET A H      1 
ATOM   289   H HA     . MET A 1 18  ? -7.711  -18.832 -7.568  1.00 50.06  ? 18  MET A HA     1 
ATOM   290   H HB2    . MET A 1 18  ? -5.048  -19.515 -6.938  1.00 45.36  ? 18  MET A HB2    1 
ATOM   291   H HB3    . MET A 1 18  ? -6.141  -20.583 -7.362  1.00 45.36  ? 18  MET A HB3    1 
ATOM   292   H HG2    . MET A 1 18  ? -5.268  -18.534 -9.087  1.00 39.96  ? 18  MET A HG2    1 
ATOM   293   H HG3    . MET A 1 18  ? -4.684  -20.009 -9.133  1.00 39.96  ? 18  MET A HG3    1 
ATOM   294   H HE1    . MET A 1 18  ? -5.757  -22.006 -10.316 1.00 33.16  ? 18  MET A HE1    1 
ATOM   295   H HE2    . MET A 1 18  ? -6.808  -22.040 -9.125  1.00 33.16  ? 18  MET A HE2    1 
ATOM   296   H HE3    . MET A 1 18  ? -7.310  -22.126 -10.629 1.00 33.16  ? 18  MET A HE3    1 
ATOM   297   N N      . ILE A 1 19  ? -8.524  -18.541 -5.124  1.00 29.09  ? 19  ILE A N      1 
ATOM   298   C CA     . ILE A 1 19  ? -8.952  -18.688 -3.736  1.00 31.87  ? 19  ILE A CA     1 
ATOM   299   C C      . ILE A 1 19  ? -9.626  -20.040 -3.486  1.00 32.12  ? 19  ILE A C      1 
ATOM   300   O O      . ILE A 1 19  ? -10.337 -20.568 -4.349  1.00 30.96  ? 19  ILE A O      1 
ATOM   301   C CB     . ILE A 1 19  ? -9.899  -17.558 -3.306  1.00 31.99  ? 19  ILE A CB     1 
ATOM   302   C CG1    . ILE A 1 19  ? -11.184 -17.555 -4.128  1.00 30.68  ? 19  ILE A CG1    1 
ATOM   303   C CG2    . ILE A 1 19  ? -9.193  -16.210 -3.426  1.00 42.29  ? 19  ILE A CG2    1 
ATOM   304   C CD1    . ILE A 1 19  ? -12.240 -16.625 -3.570  1.00 29.22  ? 19  ILE A CD1    1 
ATOM   305   H H      . ILE A 1 19  ? -9.062  -18.084 -5.615  1.00 34.90  ? 19  ILE A H      1 
ATOM   306   H HA     . ILE A 1 19  ? -8.161  -18.628 -3.180  1.00 38.25  ? 19  ILE A HA     1 
ATOM   307   H HB     . ILE A 1 19  ? -10.134 -17.696 -2.375  1.00 38.39  ? 19  ILE A HB     1 
ATOM   308   H HG12   . ILE A 1 19  ? -10.980 -17.267 -5.031  1.00 36.81  ? 19  ILE A HG12   1 
ATOM   309   H HG13   . ILE A 1 19  ? -11.566 -18.444 -4.144  1.00 36.81  ? 19  ILE A HG13   1 
ATOM   310   H HG21   . ILE A 1 19  ? -9.746  -15.524 -3.020  1.00 50.75  ? 19  ILE A HG21   1 
ATOM   311   H HG22   . ILE A 1 19  ? -8.340  -16.260 -2.967  1.00 50.75  ? 19  ILE A HG22   1 
ATOM   312   H HG23   . ILE A 1 19  ? -9.051  -16.011 -4.365  1.00 50.75  ? 19  ILE A HG23   1 
ATOM   313   H HD11   . ILE A 1 19  ? -13.060 -16.739 -4.076  1.00 35.07  ? 19  ILE A HD11   1 
ATOM   314   H HD12   . ILE A 1 19  ? -12.393 -16.845 -2.638  1.00 35.07  ? 19  ILE A HD12   1 
ATOM   315   H HD13   . ILE A 1 19  ? -11.929 -15.710 -3.647  1.00 35.07  ? 19  ILE A HD13   1 
ATOM   316   N N      . PRO A 1 20  ? -9.400  -20.611 -2.292  1.00 29.93  ? 20  PRO A N      1 
ATOM   317   C CA     . PRO A 1 20  ? -9.950  -21.927 -1.968  1.00 32.51  ? 20  PRO A CA     1 
ATOM   318   C C      . PRO A 1 20  ? -11.455 -21.903 -1.708  1.00 26.15  ? 20  PRO A C      1 
ATOM   319   O O      . PRO A 1 20  ? -12.063 -20.845 -1.551  1.00 24.23  ? 20  PRO A O      1 
ATOM   320   C CB     . PRO A 1 20  ? -9.186  -22.314 -0.697  1.00 33.42  ? 20  PRO A CB     1 
ATOM   321   C CG     . PRO A 1 20  ? -8.896  -21.019 -0.045  1.00 34.51  ? 20  PRO A CG     1 
ATOM   322   C CD     . PRO A 1 20  ? -8.639  -20.046 -1.162  1.00 33.84  ? 20  PRO A CD     1 
ATOM   323   H HA     . PRO A 1 20  ? -9.751  -22.563 -2.673  1.00 39.01  ? 20  PRO A HA     1 
ATOM   324   H HB2    . PRO A 1 20  ? -9.746  -22.868 -0.132  1.00 40.10  ? 20  PRO A HB2    1 
ATOM   325   H HB3    . PRO A 1 20  ? -8.365  -22.775 -0.932  1.00 40.10  ? 20  PRO A HB3    1 
ATOM   326   H HG2    . PRO A 1 20  ? -9.663  -20.741 0.480   1.00 41.41  ? 20  PRO A HG2    1 
ATOM   327   H HG3    . PRO A 1 20  ? -8.111  -21.107 0.518   1.00 41.41  ? 20  PRO A HG3    1 
ATOM   328   H HD2    . PRO A 1 20  ? -8.980  -19.168 -0.930  1.00 40.60  ? 20  PRO A HD2    1 
ATOM   329   H HD3    . PRO A 1 20  ? -7.693  -20.016 -1.373  1.00 40.60  ? 20  PRO A HD3    1 
ATOM   330   N N      . ARG A 1 21  ? -12.032 -23.095 -1.646  1.00 28.52  ? 21  ARG A N      1 
ATOM   331   C CA     . ARG A 1 21  ? -13.462 -23.279 -1.441  1.00 31.91  ? 21  ARG A CA     1 
ATOM   332   C C      . ARG A 1 21  ? -14.027 -22.561 -0.201  1.00 25.06  ? 21  ARG A C      1 
ATOM   333   O O      . ARG A 1 21  ? -15.053 -21.897 -0.286  1.00 24.11  ? 21  ARG A O      1 
ATOM   334   C CB     . ARG A 1 21  ? -13.755 -24.776 -1.341  1.00 28.36  ? 21  ARG A CB     1 
ATOM   335   C CG     . ARG A 1 21  ? -15.176 -25.111 -0.969  1.00 27.35  ? 21  ARG A CG     1 
ATOM   336   C CD     . ARG A 1 21  ? -15.341 -26.607 -0.894  1.00 35.98  ? 21  ARG A CD     1 
ATOM   337   N NE     . ARG A 1 21  ? -15.955 -27.112 -2.112  1.00 44.09  ? 21  ARG A NE     1 
ATOM   338   C CZ     . ARG A 1 21  ? -17.258 -27.316 -2.262  1.00 51.70  ? 21  ARG A CZ     1 
ATOM   339   N NH1    . ARG A 1 21  ? -18.103 -27.078 -1.258  1.00 45.83  ? 21  ARG A NH1    1 
ATOM   340   N NH2    . ARG A 1 21  ? -17.714 -27.769 -3.422  1.00 44.36  ? 21  ARG A NH2    1 
ATOM   341   H H      . ARG A 1 21  ? -11.602 -23.836 -1.722  1.00 34.22  ? 21  ARG A H      1 
ATOM   342   H HA     . ARG A 1 21  ? -13.933 -22.938 -2.217  1.00 38.29  ? 21  ARG A HA     1 
ATOM   343   H HB2    . ARG A 1 21  ? -13.571 -25.186 -2.200  1.00 34.03  ? 21  ARG A HB2    1 
ATOM   344   H HB3    . ARG A 1 21  ? -13.175 -25.159 -0.665  1.00 34.03  ? 21  ARG A HB3    1 
ATOM   345   H HG2    . ARG A 1 21  ? -15.391 -24.744 -0.098  1.00 32.82  ? 21  ARG A HG2    1 
ATOM   346   H HG3    . ARG A 1 21  ? -15.781 -24.766 -1.644  1.00 32.82  ? 21  ARG A HG3    1 
ATOM   347   H HD2    . ARG A 1 21  ? -14.467 -27.018 -0.808  1.00 43.17  ? 21  ARG A HD2    1 
ATOM   348   H HD3    . ARG A 1 21  ? -15.892 -26.839 -0.132  1.00 43.17  ? 21  ARG A HD3    1 
ATOM   349   H HE     . ARG A 1 21  ? -15.441 -27.290 -2.778  1.00 52.90  ? 21  ARG A HE     1 
ATOM   350   H HH11   . ARG A 1 21  ? -17.816 -26.781 -0.505  1.00 55.00  ? 21  ARG A HH11   1 
ATOM   351   H HH12   . ARG A 1 21  ? -18.945 -27.217 -1.368  1.00 55.00  ? 21  ARG A HH12   1 
ATOM   352   H HH21   . ARG A 1 21  ? -17.167 -27.926 -4.067  1.00 53.23  ? 21  ARG A HH21   1 
ATOM   353   H HH22   . ARG A 1 21  ? -18.556 -27.911 -3.527  1.00 53.23  ? 21  ARG A HH22   1 
ATOM   354   N N      . GLU A 1 22  ? -13.374 -22.718 0.946   1.00 26.89  ? 22  GLU A N      1 
ATOM   355   C CA     . GLU A 1 22  ? -13.858 -22.099 2.184   1.00 30.83  ? 22  GLU A CA     1 
ATOM   356   C C      . GLU A 1 22  ? -13.994 -20.594 2.009   1.00 28.65  ? 22  GLU A C      1 
ATOM   357   O O      . GLU A 1 22  ? -14.955 -19.979 2.485   1.00 25.55  ? 22  GLU A O      1 
ATOM   358   C CB     . GLU A 1 22  ? -12.922 -22.421 3.356   1.00 34.79  ? 22  GLU A CB     1 
ATOM   359   C CG     . GLU A 1 22  ? -11.491 -21.946 3.158   1.00 53.67  ? 22  GLU A CG     1 
ATOM   360   C CD     . GLU A 1 22  ? -10.504 -22.647 4.076   1.00 78.41  ? 22  GLU A CD     1 
ATOM   361   O OE1    . GLU A 1 22  ? -10.904 -23.054 5.190   1.00 79.15  ? 22  GLU A OE1    1 
ATOM   362   O OE2    . GLU A 1 22  ? -9.329  -22.798 3.674   1.00 64.53  ? 22  GLU A OE2    1 
ATOM   363   H H      . GLU A 1 22  ? -12.652 -23.176 1.038   1.00 32.27  ? 22  GLU A H      1 
ATOM   364   H HA     . GLU A 1 22  ? -14.735 -22.457 2.394   1.00 36.99  ? 22  GLU A HA     1 
ATOM   365   H HB2    . GLU A 1 22  ? -13.267 -21.995 4.156   1.00 41.75  ? 22  GLU A HB2    1 
ATOM   366   H HB3    . GLU A 1 22  ? -12.899 -23.383 3.481   1.00 41.75  ? 22  GLU A HB3    1 
ATOM   367   H HG2    . GLU A 1 22  ? -11.222 -22.119 2.243   1.00 64.40  ? 22  GLU A HG2    1 
ATOM   368   H HG3    . GLU A 1 22  ? -11.447 -20.995 3.342   1.00 64.40  ? 22  GLU A HG3    1 
ATOM   369   N N      . GLU A 1 23  ? -13.039 -20.003 1.303   1.00 26.62  ? 23  GLU A N      1 
ATOM   370   C CA     . GLU A 1 23  ? -13.086 -18.574 1.020   1.00 30.72  ? 23  GLU A CA     1 
ATOM   371   C C      . GLU A 1 23  ? -14.175 -18.222 0.017   1.00 23.23  ? 23  GLU A C      1 
ATOM   372   O O      . GLU A 1 23  ? -14.852 -17.216 0.178   1.00 21.19  ? 23  GLU A O      1 
ATOM   373   C CB     . GLU A 1 23  ? -11.726 -18.095 0.525   1.00 31.68  ? 23  GLU A CB     1 
ATOM   374   C CG     . GLU A 1 23  ? -10.814 -17.741 1.676   1.00 55.15  ? 23  GLU A CG     1 
ATOM   375   C CD     . GLU A 1 23  ? -11.232 -16.448 2.354   1.00 68.47  ? 23  GLU A CD     1 
ATOM   376   O OE1    . GLU A 1 23  ? -11.491 -15.455 1.635   1.00 57.55  ? 23  GLU A OE1    1 
ATOM   377   O OE2    . GLU A 1 23  ? -11.320 -16.432 3.600   1.00 66.42  ? 23  GLU A OE2    1 
ATOM   378   H H      . GLU A 1 23  ? -12.353 -20.406 0.976   1.00 31.95  ? 23  GLU A H      1 
ATOM   379   H HA     . GLU A 1 23  ? -13.285 -18.103 1.844   1.00 36.86  ? 23  GLU A HA     1 
ATOM   380   H HB2    . GLU A 1 23  ? -11.305 -18.803 0.012   1.00 38.01  ? 23  GLU A HB2    1 
ATOM   381   H HB3    . GLU A 1 23  ? -11.845 -17.307 -0.028  1.00 38.01  ? 23  GLU A HB3    1 
ATOM   382   H HG2    . GLU A 1 23  ? -10.843 -18.452 2.336   1.00 66.18  ? 23  GLU A HG2    1 
ATOM   383   H HG3    . GLU A 1 23  ? -9.910  -17.630 1.343   1.00 66.18  ? 23  GLU A HG3    1 
ATOM   384   N N      . ARG A 1 24  ? -14.363 -19.050 -1.013  1.00 24.01  ? 24  ARG A N      1 
ATOM   385   C CA     . ARG A 1 24  ? -15.455 -18.812 -1.950  1.00 21.94  ? 24  ARG A CA     1 
ATOM   386   C C      . ARG A 1 24  ? -16.802 -18.844 -1.249  1.00 20.76  ? 24  ARG A C      1 
ATOM   387   O O      . ARG A 1 24  ? -17.701 -18.060 -1.553  1.00 21.29  ? 24  ARG A O      1 
ATOM   388   C CB     . ARG A 1 24  ? -15.454 -19.845 -3.076  1.00 19.86  ? 24  ARG A CB     1 
ATOM   389   C CG     . ARG A 1 24  ? -14.302 -19.714 -4.049  1.00 25.26  ? 24  ARG A CG     1 
ATOM   390   C CD     . ARG A 1 24  ? -14.583 -20.491 -5.322  1.00 24.42  ? 24  ARG A CD     1 
ATOM   391   N NE     . ARG A 1 24  ? -14.841 -21.910 -5.078  1.00 20.98  ? 24  ARG A NE     1 
ATOM   392   C CZ     . ARG A 1 24  ? -13.908 -22.858 -5.066  1.00 27.13  ? 24  ARG A CZ     1 
ATOM   393   N NH1    . ARG A 1 24  ? -12.628 -22.553 -5.261  1.00 31.04  ? 24  ARG A NH1    1 
ATOM   394   N NH2    . ARG A 1 24  ? -14.253 -24.120 -4.848  1.00 27.38  ? 24  ARG A NH2    1 
ATOM   395   H H      . ARG A 1 24  ? -13.882 -19.741 -1.187  1.00 28.81  ? 24  ARG A H      1 
ATOM   396   H HA     . ARG A 1 24  ? -15.344 -17.934 -2.348  1.00 26.33  ? 24  ARG A HA     1 
ATOM   397   H HB2    . ARG A 1 24  ? -15.408 -20.731 -2.684  1.00 23.83  ? 24  ARG A HB2    1 
ATOM   398   H HB3    . ARG A 1 24  ? -16.277 -19.754 -3.581  1.00 23.83  ? 24  ARG A HB3    1 
ATOM   399   H HG2    . ARG A 1 24  ? -14.180 -18.780 -4.281  1.00 30.31  ? 24  ARG A HG2    1 
ATOM   400   H HG3    . ARG A 1 24  ? -13.496 -20.070 -3.644  1.00 30.31  ? 24  ARG A HG3    1 
ATOM   401   H HD2    . ARG A 1 24  ? -15.371 -20.117 -5.746  1.00 29.30  ? 24  ARG A HD2    1 
ATOM   402   H HD3    . ARG A 1 24  ? -13.824 -20.412 -5.919  1.00 29.30  ? 24  ARG A HD3    1 
ATOM   403   H HE     . ARG A 1 24  ? -15.654 -22.148 -4.932  1.00 25.18  ? 24  ARG A HE     1 
ATOM   404   H HH11   . ARG A 1 24  ? -12.391 -21.740 -5.406  1.00 37.24  ? 24  ARG A HH11   1 
ATOM   405   H HH12   . ARG A 1 24  ? -12.034 -23.175 -5.247  1.00 37.24  ? 24  ARG A HH12   1 
ATOM   406   H HH21   . ARG A 1 24  ? -15.078 -24.324 -4.716  1.00 32.86  ? 24  ARG A HH21   1 
ATOM   407   H HH22   . ARG A 1 24  ? -13.651 -24.734 -4.831  1.00 32.86  ? 24  ARG A HH22   1 
ATOM   408   N N      . ILE A 1 25  ? -16.959 -19.771 -0.316  1.00 23.48  ? 25  ILE A N      1 
ATOM   409   C CA     . ILE A 1 25  ? -18.209 -19.850 0.421   1.00 19.34  ? 25  ILE A CA     1 
ATOM   410   C C      . ILE A 1 25  ? -18.415 -18.581 1.232   1.00 20.91  ? 25  ILE A C      1 
ATOM   411   O O      . ILE A 1 25  ? -19.510 -18.032 1.258   1.00 22.36  ? 25  ILE A O      1 
ATOM   412   C CB     . ILE A 1 25  ? -18.234 -21.090 1.332   1.00 24.24  ? 25  ILE A CB     1 
ATOM   413   C CG1    . ILE A 1 25  ? -18.273 -22.349 0.462   1.00 25.26  ? 25  ILE A CG1    1 
ATOM   414   C CG2    . ILE A 1 25  ? -19.443 -21.042 2.279   1.00 26.22  ? 25  ILE A CG2    1 
ATOM   415   C CD1    . ILE A 1 25  ? -17.967 -23.637 1.206   1.00 27.86  ? 25  ILE A CD1    1 
ATOM   416   H H      . ILE A 1 25  ? -16.369 -20.356 -0.093  1.00 28.17  ? 25  ILE A H      1 
ATOM   417   H HA     . ILE A 1 25  ? -18.943 -19.926 -0.208  1.00 23.21  ? 25  ILE A HA     1 
ATOM   418   H HB     . ILE A 1 25  ? -17.422 -21.103 1.863   1.00 29.09  ? 25  ILE A HB     1 
ATOM   419   H HG12   . ILE A 1 25  ? -19.161 -22.434 0.081   1.00 30.31  ? 25  ILE A HG12   1 
ATOM   420   H HG13   . ILE A 1 25  ? -17.620 -22.259 -0.249  1.00 30.31  ? 25  ILE A HG13   1 
ATOM   421   H HG21   . ILE A 1 25  ? -19.595 -21.927 2.644   1.00 31.47  ? 25  ILE A HG21   1 
ATOM   422   H HG22   . ILE A 1 25  ? -19.260 -20.418 2.998   1.00 31.47  ? 25  ILE A HG22   1 
ATOM   423   H HG23   . ILE A 1 25  ? -20.223 -20.754 1.779   1.00 31.47  ? 25  ILE A HG23   1 
ATOM   424   H HD11   . ILE A 1 25  ? -17.903 -24.363 0.566   1.00 33.43  ? 25  ILE A HD11   1 
ATOM   425   H HD12   . ILE A 1 25  ? -17.125 -23.536 1.677   1.00 33.43  ? 25  ILE A HD12   1 
ATOM   426   H HD13   . ILE A 1 25  ? -18.680 -23.816 1.838   1.00 33.43  ? 25  ILE A HD13   1 
ATOM   427   N N      . LYS A 1 26  ? -17.357 -18.115 1.886   1.00 22.87  ? 26  LYS A N      1 
ATOM   428   C CA     . LYS A 1 26  ? -17.417 -16.858 2.628   1.00 25.56  ? 26  LYS A CA     1 
ATOM   429   C C      . LYS A 1 26  ? -17.825 -15.691 1.721   1.00 27.55  ? 26  LYS A C      1 
ATOM   430   O O      . LYS A 1 26  ? -18.723 -14.920 2.055   1.00 22.85  ? 26  LYS A O      1 
ATOM   431   C CB     . LYS A 1 26  ? -16.067 -16.571 3.285   1.00 32.57  ? 26  LYS A CB     1 
ATOM   432   C CG     . LYS A 1 26  ? -16.096 -15.422 4.280   1.00 42.57  ? 26  LYS A CG     1 
ATOM   433   C CD     . LYS A 1 26  ? -14.740 -15.235 4.955   1.00 57.12  ? 26  LYS A CD     1 
ATOM   434   C CE     . LYS A 1 26  ? -14.721 -13.999 5.850   1.00 62.80  ? 26  LYS A CE     1 
ATOM   435   N NZ     . LYS A 1 26  ? -13.349 -13.688 6.346   1.00 73.38  ? 26  LYS A NZ     1 
ATOM   436   H H      . LYS A 1 26  ? -16.592 -18.506 1.917   1.00 27.45  ? 26  LYS A H      1 
ATOM   437   H HA     . LYS A 1 26  ? -18.081 -16.938 3.330   1.00 30.67  ? 26  LYS A HA     1 
ATOM   438   H HB2    . LYS A 1 26  ? -15.775 -17.366 3.759   1.00 39.08  ? 26  LYS A HB2    1 
ATOM   439   H HB3    . LYS A 1 26  ? -15.425 -16.347 2.594   1.00 39.08  ? 26  LYS A HB3    1 
ATOM   440   H HG2    . LYS A 1 26  ? -16.320 -14.601 3.815   1.00 51.08  ? 26  LYS A HG2    1 
ATOM   441   H HG3    . LYS A 1 26  ? -16.755 -15.610 4.967   1.00 51.08  ? 26  LYS A HG3    1 
ATOM   442   H HD2    . LYS A 1 26  ? -14.547 -16.011 5.505   1.00 68.54  ? 26  LYS A HD2    1 
ATOM   443   H HD3    . LYS A 1 26  ? -14.057 -15.128 4.275   1.00 68.54  ? 26  LYS A HD3    1 
ATOM   444   H HE2    . LYS A 1 26  ? -15.037 -13.235 5.345   1.00 75.36  ? 26  LYS A HE2    1 
ATOM   445   H HE3    . LYS A 1 26  ? -15.293 -14.153 6.618   1.00 75.36  ? 26  LYS A HE3    1 
ATOM   446   H HZ1    . LYS A 1 26  ? -13.370 -12.964 6.864   1.00 88.06  ? 26  LYS A HZ1    1 
ATOM   447   H HZ2    . LYS A 1 26  ? -13.034 -14.373 6.819   1.00 88.06  ? 26  LYS A HZ2    1 
ATOM   448   H HZ3    . LYS A 1 26  ? -12.804 -13.536 5.659   1.00 88.06  ? 26  LYS A HZ3    1 
ATOM   449   N N      . ARG A 1 27  ? -17.182 -15.571 0.564   1.00 22.02  ? 27  ARG A N      1 
ATOM   450   C CA     . ARG A 1 27  ? -17.513 -14.489 -0.358  1.00 24.37  ? 27  ARG A CA     1 
ATOM   451   C C      . ARG A 1 27  ? -18.943 -14.603 -0.870  1.00 19.79  ? 27  ARG A C      1 
ATOM   452   O O      . ARG A 1 27  ? -19.630 -13.596 -1.014  1.00 21.44  ? 27  ARG A O      1 
ATOM   453   C CB     . ARG A 1 27  ? -16.545 -14.471 -1.540  1.00 22.92  ? 27  ARG A CB     1 
ATOM   454   C CG     . ARG A 1 27  ? -15.095 -14.209 -1.166  1.00 26.02  ? 27  ARG A CG     1 
ATOM   455   C CD     . ARG A 1 27  ? -14.875 -12.762 -0.765  1.00 36.56  ? 27  ARG A CD     1 
ATOM   456   N NE     . ARG A 1 27  ? -15.005 -12.563 0.672   1.00 41.82  ? 27  ARG A NE     1 
ATOM   457   C CZ     . ARG A 1 27  ? -14.099 -12.959 1.564   1.00 53.48  ? 27  ARG A CZ     1 
ATOM   458   N NH1    . ARG A 1 27  ? -14.296 -12.735 2.857   1.00 52.14  ? 27  ARG A NH1    1 
ATOM   459   N NH2    . ARG A 1 27  ? -12.999 -13.588 1.166   1.00 54.17  ? 27  ARG A NH2    1 
ATOM   460   H H      . ARG A 1 27  ? -16.558 -16.096 0.291   1.00 26.42  ? 27  ARG A H      1 
ATOM   461   H HA     . ARG A 1 27  ? -17.430 -13.643 0.108   1.00 29.24  ? 27  ARG A HA     1 
ATOM   462   H HB2    . ARG A 1 27  ? -16.582 -15.334 -1.982  1.00 27.50  ? 27  ARG A HB2    1 
ATOM   463   H HB3    . ARG A 1 27  ? -16.822 -13.777 -2.158  1.00 27.50  ? 27  ARG A HB3    1 
ATOM   464   H HG2    . ARG A 1 27  ? -14.851 -14.771 -0.415  1.00 31.23  ? 27  ARG A HG2    1 
ATOM   465   H HG3    . ARG A 1 27  ? -14.528 -14.403 -1.929  1.00 31.23  ? 27  ARG A HG3    1 
ATOM   466   H HD2    . ARG A 1 27  ? -13.984 -12.487 -1.029  1.00 43.87  ? 27  ARG A HD2    1 
ATOM   467   H HD3    . ARG A 1 27  ? -15.537 -12.206 -1.205  1.00 43.87  ? 27  ARG A HD3    1 
ATOM   468   H HE     . ARG A 1 27  ? -15.739 -12.225 0.967   1.00 50.19  ? 27  ARG A HE     1 
ATOM   469   H HH11   . ARG A 1 27  ? -15.007 -12.330 3.120   1.00 62.57  ? 27  ARG A HH11   1 
ATOM   470   H HH12   . ARG A 1 27  ? -13.711 -12.994 3.432   1.00 62.57  ? 27  ARG A HH12   1 
ATOM   471   H HH21   . ARG A 1 27  ? -12.863 -13.738 0.331   1.00 65.01  ? 27  ARG A HH21   1 
ATOM   472   H HH22   . ARG A 1 27  ? -12.418 -13.843 1.747   1.00 65.01  ? 27  ARG A HH22   1 
ATOM   473   N N      . MET A 1 28  ? -19.398 -15.823 -1.153  1.00 21.29  ? 28  MET A N      1 
ATOM   474   C CA     . MET A 1 28  ? -20.753 -16.005 -1.673  1.00 19.98  ? 28  MET A CA     1 
ATOM   475   C C      . MET A 1 28  ? -21.775 -15.568 -0.628  1.00 22.85  ? 28  MET A C      1 
ATOM   476   O O      . MET A 1 28  ? -22.774 -14.925 -0.944  1.00 24.26  ? 28  MET A O      1 
ATOM   477   C CB     . MET A 1 28  ? -20.997 -17.462 -2.077  1.00 20.46  ? 28  MET A CB     1 
ATOM   478   C CG     . MET A 1 28  ? -22.274 -17.688 -2.890  1.00 23.97  ? 28  MET A CG     1 
ATOM   479   S SD     . MET A 1 28  ? -22.183 -17.088 -4.610  1.00 25.41  ? 28  MET A SD     1 
ATOM   480   C CE     . MET A 1 28  ? -23.015 -15.518 -4.541  1.00 24.49  ? 28  MET A CE     1 
ATOM   481   H H      . MET A 1 28  ? -18.951 -16.551 -1.055  1.00 25.55  ? 28  MET A H      1 
ATOM   482   H HA     . MET A 1 28  ? -20.860 -15.455 -2.465  1.00 23.98  ? 28  MET A HA     1 
ATOM   483   H HB2    . MET A 1 28  ? -20.248 -17.765 -2.614  1.00 24.56  ? 28  MET A HB2    1 
ATOM   484   H HB3    . MET A 1 28  ? -21.061 -18.001 -1.273  1.00 24.56  ? 28  MET A HB3    1 
ATOM   485   H HG2    . MET A 1 28  ? -22.459 -18.640 -2.920  1.00 28.76  ? 28  MET A HG2    1 
ATOM   486   H HG3    . MET A 1 28  ? -23.007 -17.226 -2.454  1.00 28.76  ? 28  MET A HG3    1 
ATOM   487   H HE1    . MET A 1 28  ? -23.971 -15.670 -4.582  1.00 29.39  ? 28  MET A HE1    1 
ATOM   488   H HE2    . MET A 1 28  ? -22.784 -15.073 -3.711  1.00 29.39  ? 28  MET A HE2    1 
ATOM   489   H HE3    . MET A 1 28  ? -22.734 -14.979 -5.297  1.00 29.39  ? 28  MET A HE3    1 
ATOM   490   N N      . ARG A 1 29  ? -21.518 -15.919 0.627   1.00 22.97  ? 29  ARG A N      1 
ATOM   491   C CA     . ARG A 1 29  ? -22.417 -15.525 1.698   1.00 23.27  ? 29  ARG A CA     1 
ATOM   492   C C      . ARG A 1 29  ? -22.400 -14.005 1.893   1.00 21.74  ? 29  ARG A C      1 
ATOM   493   O O      . ARG A 1 29  ? -23.443 -13.386 2.076   1.00 22.58  ? 29  ARG A O      1 
ATOM   494   C CB     . ARG A 1 29  ? -22.045 -16.239 3.001   1.00 24.33  ? 29  ARG A CB     1 
ATOM   495   C CG     . ARG A 1 29  ? -23.105 -16.060 4.044   1.00 33.39  ? 29  ARG A CG     1 
ATOM   496   C CD     . ARG A 1 29  ? -22.961 -16.984 5.227   1.00 37.46  ? 29  ARG A CD     1 
ATOM   497   N NE     . ARG A 1 29  ? -24.216 -16.916 5.965   1.00 50.49  ? 29  ARG A NE     1 
ATOM   498   C CZ     . ARG A 1 29  ? -24.490 -16.009 6.894   1.00 48.20  ? 29  ARG A CZ     1 
ATOM   499   N NH1    . ARG A 1 29  ? -23.570 -15.112 7.249   1.00 36.90  ? 29  ARG A NH1    1 
ATOM   500   N NH2    . ARG A 1 29  ? -25.683 -16.015 7.481   1.00 36.97  ? 29  ARG A NH2    1 
ATOM   501   H H      . ARG A 1 29  ? -20.838 -16.380 0.881   1.00 27.56  ? 29  ARG A H      1 
ATOM   502   H HA     . ARG A 1 29  ? -23.321 -15.786 1.462   1.00 27.92  ? 29  ARG A HA     1 
ATOM   503   H HB2    . ARG A 1 29  ? -21.945 -17.188 2.829   1.00 29.19  ? 29  ARG A HB2    1 
ATOM   504   H HB3    . ARG A 1 29  ? -21.216 -15.870 3.343   1.00 29.19  ? 29  ARG A HB3    1 
ATOM   505   H HG2    . ARG A 1 29  ? -23.068 -15.149 4.374   1.00 40.06  ? 29  ARG A HG2    1 
ATOM   506   H HG3    . ARG A 1 29  ? -23.971 -16.228 3.641   1.00 40.06  ? 29  ARG A HG3    1 
ATOM   507   H HD2    . ARG A 1 29  ? -22.826 -17.894 4.920   1.00 44.96  ? 29  ARG A HD2    1 
ATOM   508   H HD3    . ARG A 1 29  ? -22.229 -16.698 5.794   1.00 44.96  ? 29  ARG A HD3    1 
ATOM   509   H HE     . ARG A 1 29  ? -24.819 -17.503 5.787   1.00 60.59  ? 29  ARG A HE     1 
ATOM   510   H HH11   . ARG A 1 29  ? -22.803 -15.102 6.864   1.00 44.28  ? 29  ARG A HH11   1 
ATOM   511   H HH12   . ARG A 1 29  ? -23.751 -14.532 7.858   1.00 44.28  ? 29  ARG A HH12   1 
ATOM   512   H HH21   . ARG A 1 29  ? -26.269 -16.603 7.257   1.00 44.36  ? 29  ARG A HH21   1 
ATOM   513   H HH22   . ARG A 1 29  ? -25.861 -15.444 8.098   1.00 44.36  ? 29  ARG A HH22   1 
ATOM   514   N N      . GLU A 1 30  ? -21.222 -13.399 1.824   1.00 24.17  ? 30  GLU A N      1 
ATOM   515   C CA     . GLU A 1 30  ? -21.139 -11.940 1.900   1.00 25.46  ? 30  GLU A CA     1 
ATOM   516   C C      . GLU A 1 30  ? -21.921 -11.287 0.756   1.00 28.71  ? 30  GLU A C      1 
ATOM   517   O O      . GLU A 1 30  ? -22.476 -10.201 0.919   1.00 27.30  ? 30  GLU A O      1 
ATOM   518   C CB     . GLU A 1 30  ? -19.676 -11.488 1.896   1.00 32.24  ? 30  GLU A CB     1 
ATOM   519   C CG     . GLU A 1 30  ? -18.946 -11.873 3.182   1.00 35.80  ? 30  GLU A CG     1 
ATOM   520   C CD     . GLU A 1 30  ? -17.450 -11.644 3.118   1.00 51.82  ? 30  GLU A CD     1 
ATOM   521   O OE1    . GLU A 1 30  ? -16.956 -11.172 2.069   1.00 43.10  ? 30  GLU A OE1    1 
ATOM   522   O OE2    . GLU A 1 30  ? -16.769 -11.938 4.125   1.00 57.71  ? 30  GLU A OE2    1 
ATOM   523   H H      . GLU A 1 30  ? -20.466 -13.798 1.735   1.00 29.00  ? 30  GLU A H      1 
ATOM   524   H HA     . GLU A 1 30  ? -21.537 -11.648 2.735   1.00 30.56  ? 30  GLU A HA     1 
ATOM   525   H HB2    . GLU A 1 30  ? -19.219 -11.908 1.151   1.00 38.69  ? 30  GLU A HB2    1 
ATOM   526   H HB3    . GLU A 1 30  ? -19.642 -10.523 1.807   1.00 38.69  ? 30  GLU A HB3    1 
ATOM   527   H HG2    . GLU A 1 30  ? -19.296 -11.338 3.911   1.00 42.96  ? 30  GLU A HG2    1 
ATOM   528   H HG3    . GLU A 1 30  ? -19.098 -12.813 3.363   1.00 42.96  ? 30  GLU A HG3    1 
ATOM   529   N N      . ALA A 1 31  ? -21.984 -11.961 -0.394  1.00 23.79  ? 31  ALA A N      1 
ATOM   530   C CA     . ALA A 1 31  ? -22.772 -11.477 -1.530  1.00 20.92  ? 31  ALA A CA     1 
ATOM   531   C C      . ALA A 1 31  ? -24.258 -11.854 -1.447  1.00 25.61  ? 31  ALA A C      1 
ATOM   532   O O      . ALA A 1 31  ? -24.999 -11.708 -2.421  1.00 24.59  ? 31  ALA A O      1 
ATOM   533   C CB     . ALA A 1 31  ? -22.180 -12.007 -2.840  1.00 24.48  ? 31  ALA A CB     1 
ATOM   534   H H      . ALA A 1 31  ? -21.578 -12.704 -0.543  1.00 28.54  ? 31  ALA A H      1 
ATOM   535   H HA     . ALA A 1 31  ? -22.717 -10.509 -1.558  1.00 25.11  ? 31  ALA A HA     1 
ATOM   536   H HB1    . ALA A 1 31  ? -22.700 -11.665 -3.584  1.00 29.38  ? 31  ALA A HB1    1 
ATOM   537   H HB2    . ALA A 1 31  ? -21.260 -11.708 -2.913  1.00 29.38  ? 31  ALA A HB2    1 
ATOM   538   H HB3    . ALA A 1 31  ? -22.212 -12.976 -2.831  1.00 29.38  ? 31  ALA A HB3    1 
ATOM   539   N N      . GLY A 1 32  ? -24.701 -12.337 -0.293  1.00 23.64  ? 32  GLY A N      1 
ATOM   540   C CA     . GLY A 1 32  ? -26.095 -12.725 -0.129  1.00 27.03  ? 32  GLY A CA     1 
ATOM   541   C C      . GLY A 1 32  ? -26.545 -13.846 -1.064  1.00 21.83  ? 32  GLY A C      1 
ATOM   542   O O      . GLY A 1 32  ? -27.712 -13.906 -1.442  1.00 23.74  ? 32  GLY A O      1 
ATOM   543   H H      . GLY A 1 32  ? -24.218 -12.450 0.409   1.00 28.37  ? 32  GLY A H      1 
ATOM   544   H HA2    . GLY A 1 32  ? -26.237 -13.019 0.784   1.00 32.43  ? 32  GLY A HA2    1 
ATOM   545   H HA3    . GLY A 1 32  ? -26.660 -11.953 -0.290  1.00 32.43  ? 32  GLY A HA3    1 
ATOM   546   N N      . TYR A 1 33  ? -25.615 -14.725 -1.434  1.00 23.05  ? 33  TYR A N      1 
ATOM   547   C CA     . TYR A 1 33  ? -25.878 -15.818 -2.384  1.00 25.41  ? 33  TYR A CA     1 
ATOM   548   C C      . TYR A 1 33  ? -26.455 -15.305 -3.707  1.00 25.67  ? 33  TYR A C      1 
ATOM   549   O O      . TYR A 1 33  ? -27.189 -16.014 -4.398  1.00 29.37  ? 33  TYR A O      1 
ATOM   550   C CB     . TYR A 1 33  ? -26.802 -16.869 -1.743  1.00 23.23  ? 33  TYR A CB     1 
ATOM   551   C CG     . TYR A 1 33  ? -26.163 -17.481 -0.524  1.00 25.12  ? 33  TYR A CG     1 
ATOM   552   C CD1    . TYR A 1 33  ? -25.113 -18.380 -0.650  1.00 23.94  ? 33  TYR A CD1    1 
ATOM   553   C CD2    . TYR A 1 33  ? -26.577 -17.131 0.763   1.00 28.23  ? 33  TYR A CD2    1 
ATOM   554   C CE1    . TYR A 1 33  ? -24.502 -18.926 0.457   1.00 30.16  ? 33  TYR A CE1    1 
ATOM   555   C CE2    . TYR A 1 33  ? -25.972 -17.682 1.881   1.00 29.13  ? 33  TYR A CE2    1 
ATOM   556   C CZ     . TYR A 1 33  ? -24.936 -18.576 1.723   1.00 30.92  ? 33  TYR A CZ     1 
ATOM   557   O OH     . TYR A 1 33  ? -24.316 -19.132 2.816   1.00 32.01  ? 33  TYR A OH     1 
ATOM   558   H H      . TYR A 1 33  ? -24.805 -14.712 -1.145  1.00 27.67  ? 33  TYR A H      1 
ATOM   559   H HA     . TYR A 1 33  ? -25.037 -16.256 -2.586  1.00 30.50  ? 33  TYR A HA     1 
ATOM   560   H HB2    . TYR A 1 33  ? -27.633 -16.449 -1.474  1.00 27.88  ? 33  TYR A HB2    1 
ATOM   561   H HB3    . TYR A 1 33  ? -26.975 -17.578 -2.382  1.00 27.88  ? 33  TYR A HB3    1 
ATOM   562   H HD1    . TYR A 1 33  ? -24.816 -18.618 -1.499  1.00 28.73  ? 33  TYR A HD1    1 
ATOM   563   H HD2    . TYR A 1 33  ? -27.275 -16.527 0.871   1.00 33.88  ? 33  TYR A HD2    1 
ATOM   564   H HE1    . TYR A 1 33  ? -23.804 -19.532 0.354   1.00 36.20  ? 33  TYR A HE1    1 
ATOM   565   H HE2    . TYR A 1 33  ? -26.260 -17.445 2.733   1.00 34.95  ? 33  TYR A HE2    1 
ATOM   566   H HH     . TYR A 1 33  ? -24.666 -18.843 3.523   1.00 38.41  ? 33  TYR A HH     1 
ATOM   567   N N      . ASN A 1 34  ? -26.088 -14.072 -4.058  1.00 23.09  ? 34  ASN A N      1 
ATOM   568   C CA     . ASN A 1 34  ? -26.466 -13.446 -5.324  1.00 25.43  ? 34  ASN A CA     1 
ATOM   569   C C      . ASN A 1 34  ? -25.195 -13.196 -6.145  1.00 24.40  ? 34  ASN A C      1 
ATOM   570   O O      . ASN A 1 34  ? -24.368 -12.384 -5.758  1.00 21.23  ? 34  ASN A O      1 
ATOM   571   C CB     . ASN A 1 34  ? -27.221 -12.137 -5.068  1.00 24.15  ? 34  ASN A CB     1 
ATOM   572   C CG     . ASN A 1 34  ? -27.639 -11.423 -6.344  1.00 28.25  ? 34  ASN A CG     1 
ATOM   573   O OD1    . ASN A 1 34  ? -27.240 -11.786 -7.458  1.00 26.48  ? 34  ASN A OD1    1 
ATOM   574   N ND2    . ASN A 1 34  ? -28.443 -10.383 -6.184  1.00 27.29  ? 34  ASN A ND2    1 
ATOM   575   H H      . ASN A 1 34  ? -25.603 -13.563 -3.563  1.00 27.71  ? 34  ASN A H      1 
ATOM   576   H HA     . ASN A 1 34  ? -27.044 -14.038 -5.829  1.00 30.51  ? 34  ASN A HA     1 
ATOM   577   H HB2    . ASN A 1 34  ? -28.023 -12.332 -4.559  1.00 28.98  ? 34  ASN A HB2    1 
ATOM   578   H HB3    . ASN A 1 34  ? -26.648 -11.537 -4.565  1.00 28.98  ? 34  ASN A HB3    1 
ATOM   579   H HD21   . ASN A 1 34  ? -28.713 -9.939  -6.869  1.00 32.75  ? 34  ASN A HD21   1 
ATOM   580   H HD22   . ASN A 1 34  ? -28.695 -10.152 -5.395  1.00 32.75  ? 34  ASN A HD22   1 
ATOM   581   N N      . THR A 1 35  ? -25.031 -13.894 -7.268  1.00 23.78  ? 35  THR A N      1 
ATOM   582   C CA     . THR A 1 35  ? -23.769 -13.808 -8.002  1.00 19.61  ? 35  THR A CA     1 
ATOM   583   C C      . THR A 1 35  ? -23.525 -12.405 -8.560  1.00 21.00  ? 35  THR A C      1 
ATOM   584   O O      . THR A 1 35  ? -22.377 -12.022 -8.797  1.00 20.16  ? 35  THR A O      1 
ATOM   585   C CB     . THR A 1 35  ? -23.706 -14.803 -9.173  1.00 20.42  ? 35  THR A CB     1 
ATOM   586   O OG1    . THR A 1 35  ? -24.837 -14.600 -10.023 1.00 22.46  ? 35  THR A OG1    1 
ATOM   587   C CG2    . THR A 1 35  ? -23.662 -16.241 -8.659  1.00 21.32  ? 35  THR A CG2    1 
ATOM   588   H H      . THR A 1 35  ? -25.620 -14.413 -7.620  1.00 28.54  ? 35  THR A H      1 
ATOM   589   H HA     . THR A 1 35  ? -23.041 -14.017 -7.396  1.00 23.53  ? 35  THR A HA     1 
ATOM   590   H HB     . THR A 1 35  ? -22.896 -14.641 -9.681  1.00 24.50  ? 35  THR A HB     1 
ATOM   591   H HG1    . THR A 1 35  ? -24.813 -15.139 -10.667 1.00 26.95  ? 35  THR A HG1    1 
ATOM   592   H HG21   . THR A 1 35  ? -23.638 -16.859 -9.406  1.00 25.59  ? 35  THR A HG21   1 
ATOM   593   H HG22   . THR A 1 35  ? -22.871 -16.374 -8.114  1.00 25.59  ? 35  THR A HG22   1 
ATOM   594   H HG23   . THR A 1 35  ? -24.448 -16.425 -8.123  1.00 25.59  ? 35  THR A HG23   1 
ATOM   595   N N      . PHE A 1 36  ? -24.598 -11.649 -8.789  1.00 20.25  ? 36  PHE A N      1 
ATOM   596   C CA     . PHE A 1 36  ? -24.464 -10.267 -9.257  1.00 21.54  ? 36  PHE A CA     1 
ATOM   597   C C      . PHE A 1 36  ? -23.753 -9.380  -8.236  1.00 27.52  ? 36  PHE A C      1 
ATOM   598   O O      . PHE A 1 36  ? -23.223 -8.322  -8.593  1.00 23.67  ? 36  PHE A O      1 
ATOM   599   C CB     . PHE A 1 36  ? -25.833 -9.667  -9.578  1.00 25.21  ? 36  PHE A CB     1 
ATOM   600   C CG     . PHE A 1 36  ? -25.979 -9.216  -11.002 1.00 27.33  ? 36  PHE A CG     1 
ATOM   601   C CD1    . PHE A 1 36  ? -25.262 -8.126  -11.478 1.00 27.83  ? 36  PHE A CD1    1 
ATOM   602   C CD2    . PHE A 1 36  ? -26.843 -9.869  -11.861 1.00 28.92  ? 36  PHE A CD2    1 
ATOM   603   C CE1    . PHE A 1 36  ? -25.398 -7.709  -12.790 1.00 29.70  ? 36  PHE A CE1    1 
ATOM   604   C CE2    . PHE A 1 36  ? -26.985 -9.453  -13.171 1.00 24.29  ? 36  PHE A CE2    1 
ATOM   605   C CZ     . PHE A 1 36  ? -26.259 -8.371  -13.635 1.00 30.49  ? 36  PHE A CZ     1 
ATOM   606   H H      . PHE A 1 36  ? -25.410 -11.910 -8.682  1.00 24.30  ? 36  PHE A H      1 
ATOM   607   H HA     . PHE A 1 36  ? -23.938 -10.262 -10.072 1.00 25.85  ? 36  PHE A HA     1 
ATOM   608   H HB2    . PHE A 1 36  ? -26.517 -10.333 -9.410  1.00 30.25  ? 36  PHE A HB2    1 
ATOM   609   H HB3    . PHE A 1 36  ? -25.978 -8.896  -9.007  1.00 30.25  ? 36  PHE A HB3    1 
ATOM   610   H HD1    . PHE A 1 36  ? -24.677 -7.677  -10.911 1.00 33.39  ? 36  PHE A HD1    1 
ATOM   611   H HD2    . PHE A 1 36  ? -27.332 -10.598 -11.555 1.00 34.70  ? 36  PHE A HD2    1 
ATOM   612   H HE1    . PHE A 1 36  ? -24.911 -6.980  -13.100 1.00 35.64  ? 36  PHE A HE1    1 
ATOM   613   H HE2    . PHE A 1 36  ? -27.566 -9.902  -13.741 1.00 29.15  ? 36  PHE A HE2    1 
ATOM   614   H HZ     . PHE A 1 36  ? -26.353 -8.091  -14.517 1.00 36.59  ? 36  PHE A HZ     1 
ATOM   615   N N      . LEU A 1 37  ? -23.735 -9.811  -6.974  1.00 23.76  ? 37  LEU A N      1 
ATOM   616   C CA     . LEU A 1 37  ? -23.092 -9.043  -5.910  1.00 22.34  ? 37  LEU A CA     1 
ATOM   617   C C      . LEU A 1 37  ? -21.674 -9.488  -5.623  1.00 23.92  ? 37  LEU A C      1 
ATOM   618   O O      . LEU A 1 37  ? -21.003 -8.918  -4.754  1.00 21.04  ? 37  LEU A O      1 
ATOM   619   C CB     . LEU A 1 37  ? -23.911 -9.128  -4.615  1.00 24.27  ? 37  LEU A CB     1 
ATOM   620   C CG     . LEU A 1 37  ? -25.154 -8.242  -4.551  1.00 28.86  ? 37  LEU A CG     1 
ATOM   621   C CD1    . LEU A 1 37  ? -25.888 -8.472  -3.234  1.00 32.37  ? 37  LEU A CD1    1 
ATOM   622   C CD2    . LEU A 1 37  ? -24.800 -6.759  -4.713  1.00 32.27  ? 37  LEU A CD2    1 
ATOM   623   H H      . LEU A 1 37  ? -24.090 -10.547 -6.707  1.00 28.52  ? 37  LEU A H      1 
ATOM   624   H HA     . LEU A 1 37  ? -23.051 -8.112  -6.174  1.00 26.81  ? 37  LEU A HA     1 
ATOM   625   H HB2    . LEU A 1 37  ? -24.204 -10.045 -4.500  1.00 29.13  ? 37  LEU A HB2    1 
ATOM   626   H HB3    . LEU A 1 37  ? -23.341 -8.877  -3.872  1.00 29.13  ? 37  LEU A HB3    1 
ATOM   627   H HG     . LEU A 1 37  ? -25.753 -8.487  -5.274  1.00 34.63  ? 37  LEU A HG     1 
ATOM   628   H HD11   . LEU A 1 37  ? -26.674 -7.905  -3.208  1.00 38.84  ? 37  LEU A HD11   1 
ATOM   629   H HD12   . LEU A 1 37  ? -26.150 -9.404  -3.178  1.00 38.84  ? 37  LEU A HD12   1 
ATOM   630   H HD13   . LEU A 1 37  ? -25.295 -8.250  -2.499  1.00 38.84  ? 37  LEU A HD13   1 
ATOM   631   H HD21   . LEU A 1 37  ? -25.568 -6.222  -4.461  1.00 38.72  ? 37  LEU A HD21   1 
ATOM   632   H HD22   . LEU A 1 37  ? -24.048 -6.550  -4.137  1.00 38.72  ? 37  LEU A HD22   1 
ATOM   633   H HD23   . LEU A 1 37  ? -24.566 -6.588  -5.637  1.00 38.72  ? 37  LEU A HD23   1 
ATOM   634   N N      . LEU A 1 38  ? -21.202 -10.505 -6.332  1.00 19.64  ? 38  LEU A N      1 
ATOM   635   C CA     . LEU A 1 38  ? -19.820 -10.922 -6.160  1.00 20.13  ? 38  LEU A CA     1 
ATOM   636   C C      . LEU A 1 38  ? -18.895 -9.858  -6.744  1.00 18.78  ? 38  LEU A C      1 
ATOM   637   O O      . LEU A 1 38  ? -19.191 -9.276  -7.791  1.00 20.57  ? 38  LEU A O      1 
ATOM   638   C CB     . LEU A 1 38  ? -19.550 -12.264 -6.832  1.00 18.46  ? 38  LEU A CB     1 
ATOM   639   C CG     . LEU A 1 38  ? -20.100 -13.515 -6.148  1.00 22.86  ? 38  LEU A CG     1 
ATOM   640   C CD1    . LEU A 1 38  ? -20.011 -14.698 -7.106  1.00 21.21  ? 38  LEU A CD1    1 
ATOM   641   C CD2    . LEU A 1 38  ? -19.339 -13.806 -4.877  1.00 21.77  ? 38  LEU A CD2    1 
ATOM   642   H H      . LEU A 1 38  ? -21.649 -10.962 -6.907  1.00 23.56  ? 38  LEU A H      1 
ATOM   643   H HA     . LEU A 1 38  ? -19.625 -11.010 -5.214  1.00 24.16  ? 38  LEU A HA     1 
ATOM   644   H HB2    . LEU A 1 38  ? -19.932 -12.236 -7.723  1.00 22.16  ? 38  LEU A HB2    1 
ATOM   645   H HB3    . LEU A 1 38  ? -18.589 -12.377 -6.901  1.00 22.16  ? 38  LEU A HB3    1 
ATOM   646   H HG     . LEU A 1 38  ? -21.033 -13.374 -5.921  1.00 27.43  ? 38  LEU A HG     1 
ATOM   647   H HD11   . LEU A 1 38  ? -20.352 -15.490 -6.662  1.00 25.45  ? 38  LEU A HD11   1 
ATOM   648   H HD12   . LEU A 1 38  ? -20.542 -14.506 -7.895  1.00 25.45  ? 38  LEU A HD12   1 
ATOM   649   H HD13   . LEU A 1 38  ? -19.083 -14.832 -7.356  1.00 25.45  ? 38  LEU A HD13   1 
ATOM   650   H HD21   . LEU A 1 38  ? -19.669 -14.634 -4.495  1.00 26.13  ? 38  LEU A HD21   1 
ATOM   651   H HD22   . LEU A 1 38  ? -18.396 -13.891 -5.087  1.00 26.13  ? 38  LEU A HD22   1 
ATOM   652   H HD23   . LEU A 1 38  ? -19.475 -13.076 -4.253  1.00 26.13  ? 38  LEU A HD23   1 
ATOM   653   N N      . ASN A 1 39  ? -17.783 -9.616  -6.058  1.00 20.16  ? 39  ASN A N      1 
ATOM   654   C CA     . ASN A 1 39  ? -16.711 -8.795  -6.603  1.00 20.71  ? 39  ASN A CA     1 
ATOM   655   C C      . ASN A 1 39  ? -15.976 -9.563  -7.704  1.00 20.42  ? 39  ASN A C      1 
ATOM   656   O O      . ASN A 1 39  ? -15.718 -10.774 -7.591  1.00 19.45  ? 39  ASN A O      1 
ATOM   657   C CB     . ASN A 1 39  ? -15.730 -8.374  -5.504  1.00 22.27  ? 39  ASN A CB     1 
ATOM   658   C CG     . ASN A 1 39  ? -16.391 -7.542  -4.419  1.00 24.10  ? 39  ASN A CG     1 
ATOM   659   O OD1    . ASN A 1 39  ? -17.297 -6.761  -4.689  1.00 24.06  ? 39  ASN A OD1    1 
ATOM   660   N ND2    . ASN A 1 39  ? -15.953 -7.729  -3.182  1.00 26.92  ? 39  ASN A ND2    1 
ATOM   661   H H      . ASN A 1 39  ? -17.625 -9.919  -5.269  1.00 24.20  ? 39  ASN A H      1 
ATOM   662   H HA     . ASN A 1 39  ? -17.090 -7.992  -6.994  1.00 24.85  ? 39  ASN A HA     1 
ATOM   663   H HB2    . ASN A 1 39  ? -15.360 -9.169  -5.089  1.00 26.73  ? 39  ASN A HB2    1 
ATOM   664   H HB3    . ASN A 1 39  ? -15.020 -7.844  -5.897  1.00 26.73  ? 39  ASN A HB3    1 
ATOM   665   H HD21   . ASN A 1 39  ? -16.296 -7.282  -2.532  1.00 32.31  ? 39  ASN A HD21   1 
ATOM   666   H HD22   . ASN A 1 39  ? -15.326 -8.298  -3.029  1.00 32.31  ? 39  ASN A HD22   1 
ATOM   667   N N      . SER A 1 40  ? -15.630 -8.853  -8.766  1.00 19.46  ? 40  SER A N      1 
ATOM   668   C CA     . SER A 1 40  ? -14.888 -9.448  -9.861  1.00 18.50  ? 40  SER A CA     1 
ATOM   669   C C      . SER A 1 40  ? -13.582 -10.089 -9.394  1.00 17.88  ? 40  SER A C      1 
ATOM   670   O O      . SER A 1 40  ? -13.181 -11.133 -9.900  1.00 18.45  ? 40  SER A O      1 
ATOM   671   C CB     . SER A 1 40  ? -14.601 -8.389  -10.924 1.00 18.90  ? 40  SER A CB     1 
ATOM   672   O OG     . SER A 1 40  ? -13.858 -8.953  -11.989 1.00 19.38  ? 40  SER A OG     1 
ATOM   673   H H      . SER A 1 40  ? -15.814 -8.020  -8.876  1.00 23.35  ? 40  SER A H      1 
ATOM   674   H HA     . SER A 1 40  ? -15.431 -10.141 -10.269 1.00 22.20  ? 40  SER A HA     1 
ATOM   675   H HB2    . SER A 1 40  ? -15.442 -8.049  -11.268 1.00 22.68  ? 40  SER A HB2    1 
ATOM   676   H HB3    . SER A 1 40  ? -14.090 -7.670  -10.522 1.00 22.68  ? 40  SER A HB3    1 
ATOM   677   H HG     . SER A 1 40  ? -13.741 -8.381  -12.593 1.00 23.26  ? 40  SER A HG     1 
ATOM   678   N N      . LYS A 1 41  ? -12.918 -9.486  -8.410  1.00 18.25  ? 41  LYS A N      1 
ATOM   679   C CA     . LYS A 1 41  ? -11.644 -10.027 -7.937  1.00 23.77  ? 41  LYS A CA     1 
ATOM   680   C C      . LYS A 1 41  ? -11.791 -11.409 -7.297  1.00 20.78  ? 41  LYS A C      1 
ATOM   681   O O      . LYS A 1 41  ? -10.805 -12.123 -7.108  1.00 23.91  ? 41  LYS A O      1 
ATOM   682   C CB     . LYS A 1 41  ? -10.993 -9.082  -6.925  1.00 24.10  ? 41  LYS A CB     1 
ATOM   683   C CG     . LYS A 1 41  ? -11.778 -8.913  -5.648  1.00 26.66  ? 41  LYS A CG     1 
ATOM   684   C CD     . LYS A 1 41  ? -11.027 -8.018  -4.673  1.00 30.38  ? 41  LYS A CD     1 
ATOM   685   C CE     . LYS A 1 41  ? -11.820 -7.800  -3.401  1.00 34.76  ? 41  LYS A CE     1 
ATOM   686   N NZ     . LYS A 1 41  ? -11.184 -6.766  -2.530  1.00 54.10  ? 41  LYS A NZ     1 
ATOM   687   H H      . LYS A 1 41  ? -13.178 -8.773  -8.005  1.00 21.90  ? 41  LYS A H      1 
ATOM   688   H HA     . LYS A 1 41  ? -11.042 -10.113 -8.693  1.00 28.52  ? 41  LYS A HA     1 
ATOM   689   H HB2    . LYS A 1 41  ? -10.119 -9.431  -6.691  1.00 28.92  ? 41  LYS A HB2    1 
ATOM   690   H HB3    . LYS A 1 41  ? -10.899 -8.207  -7.332  1.00 28.92  ? 41  LYS A HB3    1 
ATOM   691   H HG2    . LYS A 1 41  ? -12.633 -8.500  -5.847  1.00 31.99  ? 41  LYS A HG2    1 
ATOM   692   H HG3    . LYS A 1 41  ? -11.909 -9.776  -5.225  1.00 31.99  ? 41  LYS A HG3    1 
ATOM   693   H HD2    . LYS A 1 41  ? -10.184 -8.436  -4.438  1.00 36.45  ? 41  LYS A HD2    1 
ATOM   694   H HD3    . LYS A 1 41  ? -10.871 -7.154  -5.086  1.00 36.45  ? 41  LYS A HD3    1 
ATOM   695   H HE2    . LYS A 1 41  ? -12.713 -7.498  -3.628  1.00 41.71  ? 41  LYS A HE2    1 
ATOM   696   H HE3    . LYS A 1 41  ? -11.863 -8.632  -2.904  1.00 41.71  ? 41  LYS A HE3    1 
ATOM   697   H HZ1    . LYS A 1 41  ? -10.362 -7.022  -2.305  1.00 64.92  ? 41  LYS A HZ1    1 
ATOM   698   H HZ2    . LYS A 1 41  ? -11.136 -5.990  -2.964  1.00 64.92  ? 41  LYS A HZ2    1 
ATOM   699   H HZ3    . LYS A 1 41  ? -11.665 -6.654  -1.790  1.00 64.92  ? 41  LYS A HZ3    1 
ATOM   700   N N      . ASP A 1 42  ? -13.015 -11.771 -6.941  1.00 19.23  ? 42  ASP A N      1 
ATOM   701   C CA     . ASP A 1 42  ? -13.265 -13.057 -6.306  1.00 21.58  ? 42  ASP A CA     1 
ATOM   702   C C      . ASP A 1 42  ? -13.776 -14.118 -7.284  1.00 23.20  ? 42  ASP A C      1 
ATOM   703   O O      . ASP A 1 42  ? -14.099 -15.231 -6.870  1.00 18.90  ? 42  ASP A O      1 
ATOM   704   C CB     . ASP A 1 42  ? -14.259 -12.886 -5.166  1.00 23.21  ? 42  ASP A CB     1 
ATOM   705   C CG     . ASP A 1 42  ? -13.704 -12.031 -4.035  1.00 25.95  ? 42  ASP A CG     1 
ATOM   706   O OD1    . ASP A 1 42  ? -12.490 -12.135 -3.714  1.00 24.68  ? 42  ASP A OD1    1 
ATOM   707   O OD2    . ASP A 1 42  ? -14.492 -11.254 -3.473  1.00 24.91  ? 42  ASP A OD2    1 
ATOM   708   H H      . ASP A 1 42  ? -13.720 -11.291 -7.054  1.00 23.08  ? 42  ASP A H      1 
ATOM   709   H HA     . ASP A 1 42  ? -12.442 -13.392 -5.920  1.00 25.90  ? 42  ASP A HA     1 
ATOM   710   H HB2    . ASP A 1 42  ? -15.059 -12.455 -5.505  1.00 27.85  ? 42  ASP A HB2    1 
ATOM   711   H HB3    . ASP A 1 42  ? -14.480 -13.758 -4.802  1.00 27.85  ? 42  ASP A HB3    1 
ATOM   712   N N      . VAL A 1 43  ? -13.828 -13.771 -8.570  1.00 16.56  ? 43  VAL A N      1 
ATOM   713   C CA     . VAL A 1 43  ? -14.321 -14.676 -9.610  1.00 18.14  ? 43  VAL A CA     1 
ATOM   714   C C      . VAL A 1 43  ? -13.173 -15.158 -10.497 1.00 23.72  ? 43  VAL A C      1 
ATOM   715   O O      . VAL A 1 43  ? -12.384 -14.361 -10.995 1.00 18.06  ? 43  VAL A O      1 
ATOM   716   C CB     . VAL A 1 43  ? -15.391 -13.989 -10.480 1.00 19.04  ? 43  VAL A CB     1 
ATOM   717   C CG1    . VAL A 1 43  ? -15.867 -14.905 -11.616 1.00 18.12  ? 43  VAL A CG1    1 
ATOM   718   C CG2    . VAL A 1 43  ? -16.563 -13.559 -9.616  1.00 20.47  ? 43  VAL A CG2    1 
ATOM   719   H H      . VAL A 1 43  ? -13.580 -13.006 -8.873  1.00 19.87  ? 43  VAL A H      1 
ATOM   720   H HA     . VAL A 1 43  ? -14.729 -15.454 -9.200  1.00 21.77  ? 43  VAL A HA     1 
ATOM   721   H HB     . VAL A 1 43  ? -15.007 -13.193 -10.880 1.00 22.84  ? 43  VAL A HB     1 
ATOM   722   H HG11   . VAL A 1 43  ? -16.677 -14.534 -11.999 1.00 21.75  ? 43  VAL A HG11   1 
ATOM   723   H HG12   . VAL A 1 43  ? -15.176 -14.957 -12.295 1.00 21.75  ? 43  VAL A HG12   1 
ATOM   724   H HG13   . VAL A 1 43  ? -16.047 -15.787 -11.255 1.00 21.75  ? 43  VAL A HG13   1 
ATOM   725   H HG21   . VAL A 1 43  ? -17.244 -13.163 -10.182 1.00 24.56  ? 43  VAL A HG21   1 
ATOM   726   H HG22   . VAL A 1 43  ? -16.922 -14.337 -9.162  1.00 24.56  ? 43  VAL A HG22   1 
ATOM   727   H HG23   . VAL A 1 43  ? -16.255 -12.909 -8.966  1.00 24.56  ? 43  VAL A HG23   1 
ATOM   728   N N      . TYR A 1 44  ? -13.089 -16.474 -10.666 1.00 17.53  ? 44  TYR A N      1 
ATOM   729   C CA     . TYR A 1 44  ? -12.069 -17.129 -11.486 1.00 20.34  ? 44  TYR A CA     1 
ATOM   730   C C      . TYR A 1 44  ? -12.455 -17.082 -12.964 1.00 17.95  ? 44  TYR A C      1 
ATOM   731   O O      . TYR A 1 44  ? -11.730 -16.539 -13.796 1.00 19.54  ? 44  TYR A O      1 
ATOM   732   C CB     . TYR A 1 44  ? -11.917 -18.576 -11.001 1.00 17.57  ? 44  TYR A CB     1 
ATOM   733   C CG     . TYR A 1 44  ? -10.977 -19.486 -11.762 1.00 20.87  ? 44  TYR A CG     1 
ATOM   734   C CD1    . TYR A 1 44  ? -9.987  -18.999 -12.599 1.00 18.56  ? 44  TYR A CD1    1 
ATOM   735   C CD2    . TYR A 1 44  ? -11.091 -20.857 -11.622 1.00 19.37  ? 44  TYR A CD2    1 
ATOM   736   C CE1    . TYR A 1 44  ? -9.131  -19.867 -13.273 1.00 20.06  ? 44  TYR A CE1    1 
ATOM   737   C CE2    . TYR A 1 44  ? -10.253 -21.723 -12.288 1.00 23.09  ? 44  TYR A CE2    1 
ATOM   738   C CZ     . TYR A 1 44  ? -9.280  -21.227 -13.116 1.00 20.81  ? 44  TYR A CZ     1 
ATOM   739   O OH     . TYR A 1 44  ? -8.459  -22.126 -13.765 1.00 21.50  ? 44  TYR A OH     1 
ATOM   740   H H      . TYR A 1 44  ? -13.633 -17.031 -10.301 1.00 21.04  ? 44  TYR A H      1 
ATOM   741   H HA     . TYR A 1 44  ? -11.219 -16.675 -11.374 1.00 24.40  ? 44  TYR A HA     1 
ATOM   742   H HB2    . TYR A 1 44  ? -11.604 -18.551 -10.083 1.00 21.08  ? 44  TYR A HB2    1 
ATOM   743   H HB3    . TYR A 1 44  ? -12.793 -18.992 -11.025 1.00 21.08  ? 44  TYR A HB3    1 
ATOM   744   H HD1    . TYR A 1 44  ? -9.887  -18.081 -12.706 1.00 22.27  ? 44  TYR A HD1    1 
ATOM   745   H HD2    . TYR A 1 44  ? -11.750 -21.203 -11.064 1.00 23.24  ? 44  TYR A HD2    1 
ATOM   746   H HE1    . TYR A 1 44  ? -8.472  -19.530 -13.836 1.00 24.07  ? 44  TYR A HE1    1 
ATOM   747   H HE2    . TYR A 1 44  ? -10.350 -22.642 -12.180 1.00 27.71  ? 44  TYR A HE2    1 
ATOM   748   H HH     . TYR A 1 44  ? -7.896  -21.715 -14.234 1.00 25.81  ? 44  TYR A HH     1 
ATOM   749   N N      . VAL A 1 45  ? -13.613 -17.656 -13.263 1.00 18.65  ? 45  VAL A N      1 
ATOM   750   C CA     . VAL A 1 45  ? -14.153 -17.706 -14.621 1.00 16.36  ? 45  VAL A CA     1 
ATOM   751   C C      . VAL A 1 45  ? -15.497 -16.991 -14.616 1.00 17.10  ? 45  VAL A C      1 
ATOM   752   O O      . VAL A 1 45  ? -16.456 -17.456 -13.999 1.00 17.34  ? 45  VAL A O      1 
ATOM   753   C CB     . VAL A 1 45  ? -14.312 -19.152 -15.106 1.00 17.15  ? 45  VAL A CB     1 
ATOM   754   C CG1    . VAL A 1 45  ? -15.036 -19.210 -16.441 1.00 16.85  ? 45  VAL A CG1    1 
ATOM   755   C CG2    . VAL A 1 45  ? -12.947 -19.819 -15.213 1.00 19.70  ? 45  VAL A CG2    1 
ATOM   756   H H      . VAL A 1 45  ? -14.120 -18.035 -12.681 1.00 22.38  ? 45  VAL A H      1 
ATOM   757   H HA     . VAL A 1 45  ? -13.562 -17.242 -15.234 1.00 19.64  ? 45  VAL A HA     1 
ATOM   758   H HB     . VAL A 1 45  ? -14.836 -19.645 -14.457 1.00 20.58  ? 45  VAL A HB     1 
ATOM   759   H HG11   . VAL A 1 45  ? -14.907 -20.089 -16.830 1.00 20.22  ? 45  VAL A HG11   1 
ATOM   760   H HG12   . VAL A 1 45  ? -15.982 -19.049 -16.298 1.00 20.22  ? 45  VAL A HG12   1 
ATOM   761   H HG13   . VAL A 1 45  ? -14.667 -18.533 -17.029 1.00 20.22  ? 45  VAL A HG13   1 
ATOM   762   H HG21   . VAL A 1 45  ? -13.064 -20.728 -15.529 1.00 23.64  ? 45  VAL A HG21   1 
ATOM   763   H HG22   . VAL A 1 45  ? -12.400 -19.319 -15.838 1.00 23.64  ? 45  VAL A HG22   1 
ATOM   764   H HG23   . VAL A 1 45  ? -12.529 -19.824 -14.338 1.00 23.64  ? 45  VAL A HG23   1 
ATOM   765   N N      . ASP A 1 46  ? -15.567 -15.848 -15.283 1.00 16.14  ? 46  ASP A N      1 
ATOM   766   C CA     . ASP A 1 46  ? -16.738 -14.990 -15.160 1.00 17.90  ? 46  ASP A CA     1 
ATOM   767   C C      . ASP A 1 46  ? -17.622 -15.123 -16.387 1.00 18.14  ? 46  ASP A C      1 
ATOM   768   O O      . ASP A 1 46  ? -17.332 -14.552 -17.433 1.00 16.28  ? 46  ASP A O      1 
ATOM   769   C CB     . ASP A 1 46  ? -16.306 -13.525 -14.946 1.00 15.52  ? 46  ASP A CB     1 
ATOM   770   C CG     . ASP A 1 46  ? -17.440 -12.647 -14.441 1.00 20.87  ? 46  ASP A CG     1 
ATOM   771   O OD1    . ASP A 1 46  ? -18.595 -13.130 -14.365 1.00 17.15  ? 46  ASP A OD1    1 
ATOM   772   O OD2    . ASP A 1 46  ? -17.174 -11.462 -14.130 1.00 20.92  ? 46  ASP A OD2    1 
ATOM   773   H H      . ASP A 1 46  ? -14.957 -15.547 -15.809 1.00 19.37  ? 46  ASP A H      1 
ATOM   774   H HA     . ASP A 1 46  ? -17.259 -15.256 -14.387 1.00 21.48  ? 46  ASP A HA     1 
ATOM   775   H HB2    . ASP A 1 46  ? -15.593 -13.500 -14.289 1.00 18.62  ? 46  ASP A HB2    1 
ATOM   776   H HB3    . ASP A 1 46  ? -15.993 -13.158 -15.787 1.00 18.62  ? 46  ASP A HB3    1 
ATOM   777   N N      . LEU A 1 47  ? -18.708 -15.884 -16.248 1.00 18.41  ? 47  LEU A N      1 
ATOM   778   C CA     . LEU A 1 47  ? -19.627 -16.135 -17.362 1.00 17.50  ? 47  LEU A CA     1 
ATOM   779   C C      . LEU A 1 47  ? -20.944 -15.386 -17.177 1.00 18.31  ? 47  LEU A C      1 
ATOM   780   O O      . LEU A 1 47  ? -21.988 -15.779 -17.704 1.00 17.07  ? 47  LEU A O      1 
ATOM   781   C CB     . LEU A 1 47  ? -19.890 -17.642 -17.510 1.00 15.93  ? 47  LEU A CB     1 
ATOM   782   C CG     . LEU A 1 47  ? -18.641 -18.527 -17.603 1.00 14.70  ? 47  LEU A CG     1 
ATOM   783   C CD1    . LEU A 1 47  ? -19.014 -19.997 -17.827 1.00 17.29  ? 47  LEU A CD1    1 
ATOM   784   C CD2    . LEU A 1 47  ? -17.664 -18.058 -18.696 1.00 14.85  ? 47  LEU A CD2    1 
ATOM   785   H H      . LEU A 1 47  ? -18.937 -16.269 -15.514 1.00 22.10  ? 47  LEU A H      1 
ATOM   786   H HA     . LEU A 1 47  ? -19.224 -15.824 -18.185 1.00 21.00  ? 47  LEU A HA     1 
ATOM   787   H HB2    . LEU A 1 47  ? -20.402 -17.942 -16.743 1.00 19.11  ? 47  LEU A HB2    1 
ATOM   788   H HB3    . LEU A 1 47  ? -20.407 -17.785 -18.318 1.00 19.11  ? 47  LEU A HB3    1 
ATOM   789   H HG     . LEU A 1 47  ? -18.171 -18.476 -16.756 1.00 17.64  ? 47  LEU A HG     1 
ATOM   790   H HD11   . LEU A 1 47  ? -18.201 -20.524 -17.879 1.00 20.75  ? 47  LEU A HD11   1 
ATOM   791   H HD12   . LEU A 1 47  ? -19.559 -20.301 -17.084 1.00 20.75  ? 47  LEU A HD12   1 
ATOM   792   H HD13   . LEU A 1 47  ? -19.512 -20.073 -18.656 1.00 20.75  ? 47  LEU A HD13   1 
ATOM   793   H HD21   . LEU A 1 47  ? -16.938 -18.698 -18.765 1.00 17.81  ? 47  LEU A HD21   1 
ATOM   794   H HD22   . LEU A 1 47  ? -18.138 -18.003 -19.540 1.00 17.81  ? 47  LEU A HD22   1 
ATOM   795   H HD23   . LEU A 1 47  ? -17.315 -17.186 -18.455 1.00 17.81  ? 47  LEU A HD23   1 
ATOM   796   N N      . LEU A 1 48  ? -20.887 -14.300 -16.421 1.00 15.21  ? 48  LEU A N      1 
ATOM   797   C CA     . LEU A 1 48  ? -22.043 -13.437 -16.239 1.00 14.95  ? 48  LEU A CA     1 
ATOM   798   C C      . LEU A 1 48  ? -22.588 -12.923 -17.585 1.00 18.68  ? 48  LEU A C      1 
ATOM   799   O O      . LEU A 1 48  ? -23.798 -12.892 -17.804 1.00 18.98  ? 48  LEU A O      1 
ATOM   800   C CB     . LEU A 1 48  ? -21.668 -12.263 -15.326 1.00 18.09  ? 48  LEU A CB     1 
ATOM   801   C CG     . LEU A 1 48  ? -22.807 -11.455 -14.713 1.00 19.99  ? 48  LEU A CG     1 
ATOM   802   C CD1    . LEU A 1 48  ? -23.676 -12.312 -13.818 1.00 21.15  ? 48  LEU A CD1    1 
ATOM   803   C CD2    . LEU A 1 48  ? -22.217 -10.289 -13.940 1.00 19.82  ? 48  LEU A CD2    1 
ATOM   804   H H      . LEU A 1 48  ? -20.186 -14.037 -15.999 1.00 18.25  ? 48  LEU A H      1 
ATOM   805   H HA     . LEU A 1 48  ? -22.745 -13.948 -15.809 1.00 17.94  ? 48  LEU A HA     1 
ATOM   806   H HB2    . LEU A 1 48  ? -21.141 -12.612 -14.590 1.00 21.71  ? 48  LEU A HB2    1 
ATOM   807   H HB3    . LEU A 1 48  ? -21.126 -11.645 -15.840 1.00 21.71  ? 48  LEU A HB3    1 
ATOM   808   H HG     . LEU A 1 48  ? -23.361 -11.096 -15.423 1.00 23.98  ? 48  LEU A HG     1 
ATOM   809   H HD11   . LEU A 1 48  ? -24.406 -11.771 -13.478 1.00 25.38  ? 48  LEU A HD11   1 
ATOM   810   H HD12   . LEU A 1 48  ? -24.027 -13.056 -14.326 1.00 25.38  ? 48  LEU A HD12   1 
ATOM   811   H HD13   . LEU A 1 48  ? -23.138 -12.641 -13.081 1.00 25.38  ? 48  LEU A HD13   1 
ATOM   812   H HD21   . LEU A 1 48  ? -22.939 -9.762  -13.564 1.00 23.79  ? 48  LEU A HD21   1 
ATOM   813   H HD22   . LEU A 1 48  ? -21.654 -10.634 -13.229 1.00 23.79  ? 48  LEU A HD22   1 
ATOM   814   H HD23   . LEU A 1 48  ? -21.690 -9.744  -14.545 1.00 23.79  ? 48  LEU A HD23   1 
ATOM   815   N N      . THR A 1 49  ? -21.697 -12.542 -18.496 1.00 18.07  ? 49  THR A N      1 
ATOM   816   C CA     . THR A 1 49  ? -22.122 -12.037 -19.805 1.00 17.56  ? 49  THR A CA     1 
ATOM   817   C C      . THR A 1 49  ? -21.009 -12.070 -20.849 1.00 17.75  ? 49  THR A C      1 
ATOM   818   O O      . THR A 1 49  ? -19.829 -12.051 -20.503 1.00 18.16  ? 49  THR A O      1 
ATOM   819   C CB     . THR A 1 49  ? -22.635 -10.593 -19.711 1.00 22.15  ? 49  THR A CB     1 
ATOM   820   O OG1    . THR A 1 49  ? -23.082 -10.162 -21.003 1.00 22.89  ? 49  THR A OG1    1 
ATOM   821   C CG2    . THR A 1 49  ? -21.533 -9.671  -19.224 1.00 23.34  ? 49  THR A CG2    1 
ATOM   822   H H      . THR A 1 49  ? -20.845 -12.565 -18.385 1.00 21.69  ? 49  THR A H      1 
ATOM   823   H HA     . THR A 1 49  ? -22.852 -12.585 -20.132 1.00 21.07  ? 49  THR A HA     1 
ATOM   824   H HB     . THR A 1 49  ? -23.372 -10.551 -19.082 1.00 26.59  ? 49  THR A HB     1 
ATOM   825   H HG1    . THR A 1 49  ? -23.364 -9.372  -20.961 1.00 27.46  ? 49  THR A HG1    1 
ATOM   826   H HG21   . THR A 1 49  ? -21.888 -8.780  -19.115 1.00 28.01  ? 49  THR A HG21   1 
ATOM   827   H HG22   . THR A 1 49  ? -21.190 -9.983  -18.372 1.00 28.01  ? 49  THR A HG22   1 
ATOM   828   H HG23   . THR A 1 49  ? -20.807 -9.640  -19.866 1.00 28.01  ? 49  THR A HG23   1 
ATOM   829   N N      . ASP A 1 50  ? -21.404 -12.103 -22.124 1.00 16.78  ? 50  ASP A N      1 
ATOM   830   C CA     . ASP A 1 50  ? -20.467 -11.972 -23.243 1.00 16.27  ? 50  ASP A CA     1 
ATOM   831   C C      . ASP A 1 50  ? -20.395 -10.532 -23.744 1.00 18.49  ? 50  ASP A C      1 
ATOM   832   O O      . ASP A 1 50  ? -19.799 -10.266 -24.788 1.00 19.59  ? 50  ASP A O      1 
ATOM   833   C CB     . ASP A 1 50  ? -20.869 -12.883 -24.404 1.00 17.42  ? 50  ASP A CB     1 
ATOM   834   C CG     . ASP A 1 50  ? -22.184 -12.474 -25.038 1.00 20.96  ? 50  ASP A CG     1 
ATOM   835   O OD1    . ASP A 1 50  ? -23.085 -12.011 -24.305 1.00 20.10  ? 50  ASP A OD1    1 
ATOM   836   O OD2    . ASP A 1 50  ? -22.312 -12.611 -26.274 1.00 20.97  ? 50  ASP A OD2    1 
ATOM   837   H H      . ASP A 1 50  ? -22.222 -12.202 -22.370 1.00 20.14  ? 50  ASP A H      1 
ATOM   838   H HA     . ASP A 1 50  ? -19.579 -12.234 -22.954 1.00 19.52  ? 50  ASP A HA     1 
ATOM   839   H HB2    . ASP A 1 50  ? -20.182 -12.847 -25.088 1.00 20.91  ? 50  ASP A HB2    1 
ATOM   840   H HB3    . ASP A 1 50  ? -20.964 -13.791 -24.075 1.00 20.91  ? 50  ASP A HB3    1 
ATOM   841   N N      . SER A 1 51  ? -21.008 -9.608  -23.006 1.00 18.63  ? 51  SER A N      1 
ATOM   842   C CA     . SER A 1 51  ? -21.039 -8.217  -23.417 1.00 16.75  ? 51  SER A CA     1 
ATOM   843   C C      . SER A 1 51  ? -19.888 -7.411  -22.830 1.00 19.77  ? 51  SER A C      1 
ATOM   844   O O      . SER A 1 51  ? -19.833 -7.202  -21.619 1.00 19.05  ? 51  SER A O      1 
ATOM   845   C CB     . SER A 1 51  ? -22.354 -7.562  -23.004 1.00 21.21  ? 51  SER A CB     1 
ATOM   846   O OG     . SER A 1 51  ? -22.396 -6.236  -23.510 1.00 20.78  ? 51  SER A OG     1 
ATOM   847   H H      . SER A 1 51  ? -21.412 -9.763  -22.263 1.00 22.36  ? 51  SER A H      1 
ATOM   848   H HA     . SER A 1 51  ? -20.977 -8.165  -24.383 1.00 20.10  ? 51  SER A HA     1 
ATOM   849   H HB2    . SER A 1 51  ? -23.095 -8.071  -23.366 1.00 25.45  ? 51  SER A HB2    1 
ATOM   850   H HB3    . SER A 1 51  ? -22.408 -7.536  -22.036 1.00 25.45  ? 51  SER A HB3    1 
ATOM   851   H HG     . SER A 1 51  ? -23.118 -5.867  -23.290 1.00 24.94  ? 51  SER A HG     1 
ATOM   852   N N      . GLY A 1 52  ? -18.984 -6.954  -23.693 1.00 19.00  ? 52  GLY A N      1 
ATOM   853   C CA     . GLY A 1 52  ? -17.911 -6.055  -23.292 1.00 17.85  ? 52  GLY A CA     1 
ATOM   854   C C      . GLY A 1 52  ? -16.804 -6.702  -22.491 1.00 17.94  ? 52  GLY A C      1 
ATOM   855   O O      . GLY A 1 52  ? -15.919 -6.020  -21.974 1.00 15.31  ? 52  GLY A O      1 
ATOM   856   H H      . GLY A 1 52  ? -18.973 -7.155  -24.529 1.00 22.81  ? 52  GLY A H      1 
ATOM   857   H HA2    . GLY A 1 52  ? -17.517 -5.665  -24.087 1.00 21.42  ? 52  GLY A HA2    1 
ATOM   858   H HA3    . GLY A 1 52  ? -18.285 -5.336  -22.759 1.00 21.42  ? 52  GLY A HA3    1 
ATOM   859   N N      . THR A 1 53  ? -16.837 -8.028  -22.425 1.00 16.11  ? 53  THR A N      1 
ATOM   860   C CA     . THR A 1 53  ? -15.882 -8.811  -21.642 1.00 16.39  ? 53  THR A CA     1 
ATOM   861   C C      . THR A 1 53  ? -14.826 -9.512  -22.507 1.00 16.99  ? 53  THR A C      1 
ATOM   862   O O      . THR A 1 53  ? -14.030 -10.312 -22.008 1.00 16.88  ? 53  THR A O      1 
ATOM   863   C CB     . THR A 1 53  ? -16.634 -9.874  -20.819 1.00 18.69  ? 53  THR A CB     1 
ATOM   864   O OG1    . THR A 1 53  ? -17.561 -10.542 -21.678 1.00 16.60  ? 53  THR A OG1    1 
ATOM   865   C CG2    . THR A 1 53  ? -17.408 -9.227  -19.667 1.00 19.25  ? 53  THR A CG2    1 
ATOM   866   H H      . THR A 1 53  ? -17.416 -8.513  -22.835 1.00 19.33  ? 53  THR A H      1 
ATOM   867   H HA     . THR A 1 53  ? -15.420 -8.228  -21.020 1.00 19.67  ? 53  THR A HA     1 
ATOM   868   H HB     . THR A 1 53  ? -16.006 -10.515 -20.451 1.00 22.42  ? 53  THR A HB     1 
ATOM   869   H HG1    . THR A 1 53  ? -18.000 -11.109 -21.241 1.00 19.92  ? 53  THR A HG1    1 
ATOM   870   H HG21   . THR A 1 53  ? -17.884 -9.907  -19.165 1.00 23.10  ? 53  THR A HG21   1 
ATOM   871   H HG22   . THR A 1 53  ? -16.794 -8.768  -19.072 1.00 23.10  ? 53  THR A HG22   1 
ATOM   872   H HG23   . THR A 1 53  ? -18.048 -8.587  -20.016 1.00 23.10  ? 53  THR A HG23   1 
ATOM   873   N N      . ASN A 1 54  ? -14.812 -9.194  -23.796 1.00 15.76  ? 54  ASN A N      1 
ATOM   874   C CA     . ASN A 1 54  ? -13.957 -9.874  -24.764 1.00 12.96  ? 54  ASN A CA     1 
ATOM   875   C C      . ASN A 1 54  ? -12.478 -9.535  -24.617 1.00 15.96  ? 54  ASN A C      1 
ATOM   876   O O      . ASN A 1 54  ? -12.128 -8.447  -24.141 1.00 15.77  ? 54  ASN A O      1 
ATOM   877   C CB     . ASN A 1 54  ? -14.389 -9.519  -26.184 1.00 15.89  ? 54  ASN A CB     1 
ATOM   878   C CG     . ASN A 1 54  ? -15.876 -9.676  -26.400 1.00 18.23  ? 54  ASN A CG     1 
ATOM   879   O OD1    . ASN A 1 54  ? -16.415 -10.781 -26.321 1.00 19.09  ? 54  ASN A OD1    1 
ATOM   880   N ND2    . ASN A 1 54  ? -16.549 -8.570  -26.670 1.00 15.17  ? 54  ASN A ND2    1 
ATOM   881   H H      . ASN A 1 54  ? -15.296 -8.574  -24.143 1.00 18.92  ? 54  ASN A H      1 
ATOM   882   H HA     . ASN A 1 54  ? -14.056 -10.832 -24.652 1.00 15.55  ? 54  ASN A HA     1 
ATOM   883   H HB2    . ASN A 1 54  ? -14.155 -8.595  -26.363 1.00 19.07  ? 54  ASN A HB2    1 
ATOM   884   H HB3    . ASN A 1 54  ? -13.932 -10.104 -26.809 1.00 19.07  ? 54  ASN A HB3    1 
ATOM   885   H HD21   . ASN A 1 54  ? -17.398 -8.605  -26.802 1.00 18.21  ? 54  ASN A HD21   1 
ATOM   886   H HD22   . ASN A 1 54  ? -16.138 -7.816  -26.713 1.00 18.21  ? 54  ASN A HD22   1 
ATOM   887   N N      . ALA A 1 55  ? -11.612 -10.453 -25.043 1.00 14.56  ? 55  ALA A N      1 
ATOM   888   C CA     . ALA A 1 55  ? -10.185 -10.160 -25.126 1.00 15.24  ? 55  ALA A CA     1 
ATOM   889   C C      . ALA A 1 55  ? -9.884  -9.563  -26.491 1.00 13.45  ? 55  ALA A C      1 
ATOM   890   O O      . ALA A 1 55  ? -10.253 -10.126 -27.529 1.00 16.33  ? 55  ALA A O      1 
ATOM   891   C CB     . ALA A 1 55  ? -9.335  -11.426 -24.889 1.00 16.01  ? 55  ALA A CB     1 
ATOM   892   H H      . ALA A 1 55  ? -11.825 -11.249 -25.289 1.00 17.47  ? 55  ALA A H      1 
ATOM   893   H HA     . ALA A 1 55  ? -9.944  -9.509  -24.449 1.00 18.29  ? 55  ALA A HA     1 
ATOM   894   H HB1    . ALA A 1 55  ? -8.396  -11.192 -24.952 1.00 19.21  ? 55  ALA A HB1    1 
ATOM   895   H HB2    . ALA A 1 55  ? -9.531  -11.776 -24.006 1.00 19.21  ? 55  ALA A HB2    1 
ATOM   896   H HB3    . ALA A 1 55  ? -9.558  -12.086 -25.564 1.00 19.21  ? 55  ALA A HB3    1 
ATOM   897   N N      . MET A 1 56  ? -9.206  -8.422  -26.479 1.00 13.97  ? 56  MET A N      1 
ATOM   898   C CA     . MET A 1 56  ? -8.761  -7.781  -27.704 1.00 13.20  ? 56  MET A CA     1 
ATOM   899   C C      . MET A 1 56  ? -7.450  -8.378  -28.191 1.00 17.04  ? 56  MET A C      1 
ATOM   900   O O      . MET A 1 56  ? -6.764  -9.063  -27.443 1.00 15.04  ? 56  MET A O      1 
ATOM   901   C CB     . MET A 1 56  ? -8.605  -6.274  -27.474 1.00 14.51  ? 56  MET A CB     1 
ATOM   902   C CG     . MET A 1 56  ? -9.919  -5.583  -27.186 1.00 14.30  ? 56  MET A CG     1 
ATOM   903   S SD     . MET A 1 56  ? -9.830  -3.822  -27.511 1.00 16.41  ? 56  MET A SD     1 
ATOM   904   C CE     . MET A 1 56  ? -8.813  -3.244  -26.151 1.00 18.28  ? 56  MET A CE     1 
ATOM   905   H H      . MET A 1 56  ? -8.990  -7.996  -25.764 1.00 16.77  ? 56  MET A H      1 
ATOM   906   H HA     . MET A 1 56  ? -9.438  -7.909  -28.385 1.00 15.84  ? 56  MET A HA     1 
ATOM   907   H HB2    . MET A 1 56  ? -8.018  -6.130  -26.715 1.00 17.42  ? 56  MET A HB2    1 
ATOM   908   H HB3    . MET A 1 56  ? -8.223  -5.871  -28.270 1.00 17.42  ? 56  MET A HB3    1 
ATOM   909   H HG2    . MET A 1 56  ? -10.610 -5.961  -27.753 1.00 17.16  ? 56  MET A HG2    1 
ATOM   910   H HG3    . MET A 1 56  ? -10.147 -5.708  -26.251 1.00 17.16  ? 56  MET A HG3    1 
ATOM   911   H HE1    . MET A 1 56  ? -8.702  -2.283  -26.227 1.00 21.93  ? 56  MET A HE1    1 
ATOM   912   H HE2    . MET A 1 56  ? -9.252  -3.462  -25.314 1.00 21.93  ? 56  MET A HE2    1 
ATOM   913   H HE3    . MET A 1 56  ? -7.949  -3.682  -26.196 1.00 21.93  ? 56  MET A HE3    1 
ATOM   914   N N      . SER A 1 57  ? -7.110  -8.104  -29.448 1.00 13.04  ? 57  SER A N      1 
ATOM   915   C CA     . SER A 1 57  ? -5.861  -8.564  -30.050 1.00 13.87  ? 57  SER A CA     1 
ATOM   916   C C      . SER A 1 57  ? -4.715  -7.576  -29.854 1.00 17.39  ? 57  SER A C      1 
ATOM   917   O O      . SER A 1 57  ? -4.931  -6.427  -29.464 1.00 13.74  ? 57  SER A O      1 
ATOM   918   C CB     . SER A 1 57  ? -6.044  -8.775  -31.543 1.00 14.62  ? 57  SER A CB     1 
ATOM   919   O OG     . SER A 1 57  ? -6.212  -7.512  -32.171 1.00 18.07  ? 57  SER A OG     1 
ATOM   920   H H      . SER A 1 57  ? -7.598  -7.642  -29.985 1.00 15.65  ? 57  SER A H      1 
ATOM   921   H HA     . SER A 1 57  ? -5.605  -9.410  -29.654 1.00 16.64  ? 57  SER A HA     1 
ATOM   922   H HB2    . SER A 1 57  ? -5.257  -9.212  -31.905 1.00 17.55  ? 57  SER A HB2    1 
ATOM   923   H HB3    . SER A 1 57  ? -6.833  -9.318  -31.696 1.00 17.55  ? 57  SER A HB3    1 
ATOM   924   H HG     . SER A 1 57  ? -6.209  -7.604  -33.005 1.00 21.68  ? 57  SER A HG     1 
ATOM   925   N N      . ASP A 1 58  ? -3.504  -8.025  -30.183 1.00 15.99  ? 58  ASP A N      1 
ATOM   926   C CA     . ASP A 1 58  ? -2.349  -7.140  -30.230 1.00 14.76  ? 58  ASP A CA     1 
ATOM   927   C C      . ASP A 1 58  ? -2.591  -6.022  -31.239 1.00 16.49  ? 58  ASP A C      1 
ATOM   928   O O      . ASP A 1 58  ? -2.232  -4.877  -30.997 1.00 15.78  ? 58  ASP A O      1 
ATOM   929   C CB     . ASP A 1 58  ? -1.066  -7.923  -30.565 1.00 21.50  ? 58  ASP A CB     1 
ATOM   930   C CG     . ASP A 1 58  ? -1.184  -8.802  -31.823 1.00 25.73  ? 58  ASP A CG     1 
ATOM   931   O OD1    . ASP A 1 58  ? -2.296  -9.020  -32.362 1.00 20.68  ? 58  ASP A OD1    1 
ATOM   932   O OD2    . ASP A 1 58  ? -0.125  -9.310  -32.253 1.00 27.39  ? 58  ASP A OD2    1 
ATOM   933   H H      . ASP A 1 58  ? -3.328  -8.843  -30.383 1.00 19.19  ? 58  ASP A H      1 
ATOM   934   H HA     . ASP A 1 58  ? -2.230  -6.733  -29.358 1.00 17.71  ? 58  ASP A HA     1 
ATOM   935   H HB2    . ASP A 1 58  ? -0.344  -7.292  -30.711 1.00 25.80  ? 58  ASP A HB2    1 
ATOM   936   H HB3    . ASP A 1 58  ? -0.850  -8.502  -29.818 1.00 25.80  ? 58  ASP A HB3    1 
ATOM   937   N N      . LYS A 1 59  ? -3.224  -6.342  -32.358 1.00 16.16  ? 59  LYS A N      1 
ATOM   938   C CA     . LYS A 1 59  ? -3.523  -5.314  -33.357 1.00 16.06  ? 59  LYS A CA     1 
ATOM   939   C C      . LYS A 1 59  ? -4.467  -4.252  -32.807 1.00 15.34  ? 59  LYS A C      1 
ATOM   940   O O      . LYS A 1 59  ? -4.297  -3.056  -33.068 1.00 15.41  ? 59  LYS A O      1 
ATOM   941   C CB     . LYS A 1 59  ? -4.136  -5.941  -34.607 1.00 21.30  ? 59  LYS A CB     1 
ATOM   942   C CG     . LYS A 1 59  ? -3.201  -6.879  -35.363 1.00 33.52  ? 59  LYS A CG     1 
ATOM   943   C CD     . LYS A 1 59  ? -2.166  -6.102  -36.156 1.00 46.23  ? 59  LYS A CD     1 
ATOM   944   C CE     . LYS A 1 59  ? -1.570  -6.940  -37.288 1.00 71.74  ? 59  LYS A CE     1 
ATOM   945   N NZ     . LYS A 1 59  ? -1.084  -8.282  -36.844 1.00 75.41  ? 59  LYS A NZ     1 
ATOM   946   H H      . LYS A 1 59  ? -3.490  -7.133  -32.566 1.00 19.39  ? 59  LYS A H      1 
ATOM   947   H HA     . LYS A 1 59  ? -2.697  -4.876  -33.616 1.00 19.28  ? 59  LYS A HA     1 
ATOM   948   H HB2    . LYS A 1 59  ? -4.917  -6.453  -34.345 1.00 25.56  ? 59  LYS A HB2    1 
ATOM   949   H HB3    . LYS A 1 59  ? -4.400  -5.232  -35.214 1.00 25.56  ? 59  LYS A HB3    1 
ATOM   950   H HG2    . LYS A 1 59  ? -2.736  -7.448  -34.730 1.00 40.22  ? 59  LYS A HG2    1 
ATOM   951   H HG3    . LYS A 1 59  ? -3.718  -7.417  -35.982 1.00 40.22  ? 59  LYS A HG3    1 
ATOM   952   H HD2    . LYS A 1 59  ? -2.586  -5.322  -36.550 1.00 55.48  ? 59  LYS A HD2    1 
ATOM   953   H HD3    . LYS A 1 59  ? -1.448  -5.830  -35.567 1.00 55.48  ? 59  LYS A HD3    1 
ATOM   954   H HE2    . LYS A 1 59  ? -2.249  -7.079  -37.966 1.00 86.09  ? 59  LYS A HE2    1 
ATOM   955   H HE3    . LYS A 1 59  ? -0.817  -6.462  -37.669 1.00 86.09  ? 59  LYS A HE3    1 
ATOM   956   H HZ1    . LYS A 1 59  ? -0.277  -8.207  -36.478 1.00 90.50  ? 59  LYS A HZ1    1 
ATOM   957   H HZ2    . LYS A 1 59  ? -1.643  -8.632  -36.247 1.00 90.50  ? 59  LYS A HZ2    1 
ATOM   958   H HZ3    . LYS A 1 59  ? -1.029  -8.829  -37.544 1.00 90.50  ? 59  LYS A HZ3    1 
ATOM   959   N N      . GLN A 1 60  ? -5.469  -4.685  -32.050 1.00 13.20  ? 60  GLN A N      1 
ATOM   960   C CA     . GLN A 1 60  ? -6.398  -3.737  -31.438 1.00 15.91  ? 60  GLN A CA     1 
ATOM   961   C C      . GLN A 1 60  ? -5.703  -2.864  -30.395 1.00 12.12  ? 60  GLN A C      1 
ATOM   962   O O      . GLN A 1 60  ? -5.965  -1.665  -30.305 1.00 15.46  ? 60  GLN A O      1 
ATOM   963   C CB     . GLN A 1 60  ? -7.567  -4.479  -30.799 1.00 14.99  ? 60  GLN A CB     1 
ATOM   964   C CG     . GLN A 1 60  ? -8.582  -5.007  -31.797 1.00 14.99  ? 60  GLN A CG     1 
ATOM   965   C CD     . GLN A 1 60  ? -9.630  -5.851  -31.105 1.00 15.48  ? 60  GLN A CD     1 
ATOM   966   O OE1    . GLN A 1 60  ? -9.335  -6.944  -30.637 1.00 16.05  ? 60  GLN A OE1    1 
ATOM   967   N NE2    . GLN A 1 60  ? -10.846 -5.326  -30.992 1.00 13.35  ? 60  GLN A NE2    1 
ATOM   968   H H      . GLN A 1 60  ? -5.633  -5.511  -31.876 1.00 15.84  ? 60  GLN A H      1 
ATOM   969   H HA     . GLN A 1 60  ? -6.754  -3.154  -32.127 1.00 19.09  ? 60  GLN A HA     1 
ATOM   970   H HB2    . GLN A 1 60  ? -7.221  -5.236  -30.301 1.00 17.99  ? 60  GLN A HB2    1 
ATOM   971   H HB3    . GLN A 1 60  ? -8.030  -3.874  -30.198 1.00 17.99  ? 60  GLN A HB3    1 
ATOM   972   H HG2    . GLN A 1 60  ? -9.026  -4.261  -32.230 1.00 17.99  ? 60  GLN A HG2    1 
ATOM   973   H HG3    . GLN A 1 60  ? -8.130  -5.559  -32.455 1.00 17.99  ? 60  GLN A HG3    1 
ATOM   974   H HE21   . GLN A 1 60  ? -11.006 -4.541  -31.305 1.00 16.02  ? 60  GLN A HE21   1 
ATOM   975   H HE22   . GLN A 1 60  ? -11.472 -5.771  -30.606 1.00 16.02  ? 60  GLN A HE22   1 
ATOM   976   N N      . TRP A 1 61  ? -4.819  -3.461  -29.603 1.00 12.92  ? 61  TRP A N      1 
ATOM   977   C CA     . TRP A 1 61  ? -4.107  -2.708  -28.580 1.00 13.62  ? 61  TRP A CA     1 
ATOM   978   C C      . TRP A 1 61  ? -3.116  -1.723  -29.214 1.00 15.98  ? 61  TRP A C      1 
ATOM   979   O O      . TRP A 1 61  ? -2.906  -0.622  -28.694 1.00 17.86  ? 61  TRP A O      1 
ATOM   980   C CB     . TRP A 1 61  ? -3.407  -3.672  -27.602 1.00 15.61  ? 61  TRP A CB     1 
ATOM   981   C CG     . TRP A 1 61  ? -4.332  -4.042  -26.464 1.00 15.34  ? 61  TRP A CG     1 
ATOM   982   C CD1    . TRP A 1 61  ? -5.004  -5.219  -26.286 1.00 16.18  ? 61  TRP A CD1    1 
ATOM   983   C CD2    . TRP A 1 61  ? -4.713  -3.198  -25.378 1.00 15.67  ? 61  TRP A CD2    1 
ATOM   984   N NE1    . TRP A 1 61  ? -5.769  -5.162  -25.141 1.00 15.95  ? 61  TRP A NE1    1 
ATOM   985   C CE2    . TRP A 1 61  ? -5.611  -3.923  -24.569 1.00 16.20  ? 61  TRP A CE2    1 
ATOM   986   C CE3    . TRP A 1 61  ? -4.381  -1.888  -25.006 1.00 20.05  ? 61  TRP A CE3    1 
ATOM   987   C CZ2    . TRP A 1 61  ? -6.179  -3.391  -23.412 1.00 16.39  ? 61  TRP A CZ2    1 
ATOM   988   C CZ3    . TRP A 1 61  ? -4.939  -1.360  -23.864 1.00 19.18  ? 61  TRP A CZ3    1 
ATOM   989   C CH2    . TRP A 1 61  ? -5.830  -2.113  -23.074 1.00 19.73  ? 61  TRP A CH2    1 
ATOM   990   H H      . TRP A 1 61  ? -4.615  -4.296  -29.638 1.00 15.51  ? 61  TRP A H      1 
ATOM   991   H HA     . TRP A 1 61  ? -4.750  -2.190  -28.071 1.00 16.35  ? 61  TRP A HA     1 
ATOM   992   H HB2    . TRP A 1 61  ? -3.157  -4.484  -28.071 1.00 18.73  ? 61  TRP A HB2    1 
ATOM   993   H HB3    . TRP A 1 61  ? -2.622  -3.241  -27.231 1.00 18.73  ? 61  TRP A HB3    1 
ATOM   994   H HD1    . TRP A 1 61  ? -4.947  -5.955  -26.852 1.00 19.42  ? 61  TRP A HD1    1 
ATOM   995   H HE1    . TRP A 1 61  ? -6.269  -5.794  -24.840 1.00 19.15  ? 61  TRP A HE1    1 
ATOM   996   H HE3    . TRP A 1 61  ? -3.796  -1.383  -25.524 1.00 24.06  ? 61  TRP A HE3    1 
ATOM   997   H HZ2    . TRP A 1 61  ? -6.763  -3.889  -22.886 1.00 19.67  ? 61  TRP A HZ2    1 
ATOM   998   H HZ3    . TRP A 1 61  ? -4.723  -0.492  -23.609 1.00 23.02  ? 61  TRP A HZ3    1 
ATOM   999   H HH2    . TRP A 1 61  ? -6.189  -1.732  -22.305 1.00 23.68  ? 61  TRP A HH2    1 
ATOM   1000  N N      . ALA A 1 62  ? -2.524  -2.104  -30.340 1.00 13.40  ? 62  ALA A N      1 
ATOM   1001  C CA     . ALA A 1 62  ? -1.703  -1.169  -31.111 1.00 15.61  ? 62  ALA A CA     1 
ATOM   1002  C C      . ALA A 1 62  ? -2.569  0.018   -31.515 1.00 16.58  ? 62  ALA A C      1 
ATOM   1003  O O      . ALA A 1 62  ? -2.176  1.180   -31.356 1.00 15.88  ? 62  ALA A O      1 
ATOM   1004  C CB     . ALA A 1 62  ? -1.103  -1.844  -32.334 1.00 17.25  ? 62  ALA A CB     1 
ATOM   1005  H H      . ALA A 1 62  ? -2.579  -2.892  -30.680 1.00 16.08  ? 62  ALA A H      1 
ATOM   1006  H HA     . ALA A 1 62  ? -0.978  -0.843  -30.555 1.00 18.73  ? 62  ALA A HA     1 
ATOM   1007  H HB1    . ALA A 1 62  ? -0.545  -1.206  -32.805 1.00 20.70  ? 62  ALA A HB1    1 
ATOM   1008  H HB2    . ALA A 1 62  ? -0.570  -2.600  -32.044 1.00 20.70  ? 62  ALA A HB2    1 
ATOM   1009  H HB3    . ALA A 1 62  ? -1.821  -2.147  -32.911 1.00 20.70  ? 62  ALA A HB3    1 
ATOM   1010  N N      . GLY A 1 63  ? -3.770  -0.271  -32.002 1.00 15.88  ? 63  GLY A N      1 
ATOM   1011  C CA     . GLY A 1 63  ? -4.721  0.786   -32.324 1.00 14.67  ? 63  GLY A CA     1 
ATOM   1012  C C      . GLY A 1 63  ? -5.072  1.649   -31.123 1.00 15.67  ? 63  GLY A C      1 
ATOM   1013  O O      . GLY A 1 63  ? -5.284  2.856   -31.269 1.00 18.04  ? 63  GLY A O      1 
ATOM   1014  H H      . GLY A 1 63  ? -4.058  -1.067  -32.155 1.00 19.06  ? 63  GLY A H      1 
ATOM   1015  H HA2    . GLY A 1 63  ? -4.346  1.358   -33.012 1.00 17.60  ? 63  GLY A HA2    1 
ATOM   1016  H HA3    . GLY A 1 63  ? -5.538  0.391   -32.666 1.00 17.60  ? 63  GLY A HA3    1 
ATOM   1017  N N      . MET A 1 64  ? -5.123  1.047   -29.935 1.00 15.85  ? 64  MET A N      1 
ATOM   1018  C CA     . MET A 1 64  ? -5.447  1.776   -28.703 1.00 19.56  ? 64  MET A CA     1 
ATOM   1019  C C      . MET A 1 64  ? -4.361  2.801   -28.351 1.00 18.38  ? 64  MET A C      1 
ATOM   1020  O O      . MET A 1 64  ? -4.625  3.773   -27.647 1.00 18.92  ? 64  MET A O      1 
ATOM   1021  C CB     . MET A 1 64  ? -5.633  0.810   -27.522 1.00 20.12  ? 64  MET A CB     1 
ATOM   1022  C CG     . MET A 1 64  ? -6.886  -0.083  -27.607 1.00 23.77  ? 64  MET A CG     1 
ATOM   1023  S SD     . MET A 1 64  ? -8.398  0.696   -26.999 1.00 23.03  ? 64  MET A SD     1 
ATOM   1024  C CE     . MET A 1 64  ? -8.006  0.855   -25.269 1.00 20.94  ? 64  MET A CE     1 
ATOM   1025  H H      . MET A 1 64  ? -4.973  0.209   -29.813 1.00 19.02  ? 64  MET A H      1 
ATOM   1026  H HA     . MET A 1 64  ? -6.286  2.246   -28.833 1.00 23.47  ? 64  MET A HA     1 
ATOM   1027  H HB2    . MET A 1 64  ? -4.862  0.225   -27.473 1.00 24.15  ? 64  MET A HB2    1 
ATOM   1028  H HB3    . MET A 1 64  ? -5.693  1.332   -26.708 1.00 24.15  ? 64  MET A HB3    1 
ATOM   1029  H HG2    . MET A 1 64  ? -7.036  -0.320  -28.534 1.00 28.52  ? 64  MET A HG2    1 
ATOM   1030  H HG3    . MET A 1 64  ? -6.734  -0.885  -27.083 1.00 28.52  ? 64  MET A HG3    1 
ATOM   1031  H HE1    . MET A 1 64  ? -8.743  1.300   -24.824 1.00 25.12  ? 64  MET A HE1    1 
ATOM   1032  H HE2    . MET A 1 64  ? -7.874  -0.029  -24.892 1.00 25.12  ? 64  MET A HE2    1 
ATOM   1033  H HE3    . MET A 1 64  ? -7.199  1.382   -25.169 1.00 25.12  ? 64  MET A HE3    1 
ATOM   1034  N N      . MET A 1 65  ? -3.142  2.570   -28.827 1.00 15.76  ? 65  MET A N      1 
ATOM   1035  C CA     . MET A 1 65  ? -2.052  3.534   -28.649 1.00 19.22  ? 65  MET A CA     1 
ATOM   1036  C C      . MET A 1 65  ? -2.129  4.671   -29.688 1.00 16.23  ? 65  MET A C      1 
ATOM   1037  O O      . MET A 1 65  ? -1.445  5.678   -29.551 1.00 18.70  ? 65  MET A O      1 
ATOM   1038  C CB     . MET A 1 65  ? -0.691  2.837   -28.759 1.00 15.78  ? 65  MET A CB     1 
ATOM   1039  C CG     . MET A 1 65  ? -0.451  1.761   -27.725 1.00 20.84  ? 65  MET A CG     1 
ATOM   1040  S SD     . MET A 1 65  ? -0.466  2.455   -26.081 1.00 27.85  ? 65  MET A SD     1 
ATOM   1041  C CE     . MET A 1 65  ? -1.779  1.499   -25.374 1.00 29.22  ? 65  MET A CE     1 
ATOM   1042  H H      . MET A 1 65  ? -2.915  1.861   -29.258 1.00 18.91  ? 65  MET A H      1 
ATOM   1043  H HA     . MET A 1 65  ? -2.117  3.921   -27.763 1.00 23.07  ? 65  MET A HA     1 
ATOM   1044  H HB2    . MET A 1 65  ? -0.624  2.424   -29.634 1.00 18.93  ? 65  MET A HB2    1 
ATOM   1045  H HB3    . MET A 1 65  ? 0.007   3.503   -28.658 1.00 18.93  ? 65  MET A HB3    1 
ATOM   1046  H HG2    . MET A 1 65  ? -1.153  1.095   -27.783 1.00 25.01  ? 65  MET A HG2    1 
ATOM   1047  H HG3    . MET A 1 65  ? 0.416   1.354   -27.878 1.00 25.01  ? 65  MET A HG3    1 
ATOM   1048  H HE1    . MET A 1 65  ? -1.828  1.685   -24.423 1.00 35.06  ? 65  MET A HE1    1 
ATOM   1049  H HE2    . MET A 1 65  ? -2.614  1.743   -25.803 1.00 35.06  ? 65  MET A HE2    1 
ATOM   1050  H HE3    . MET A 1 65  ? -1.595  0.557   -25.517 1.00 35.06  ? 65  MET A HE3    1 
ATOM   1051  N N      . MET A 1 66  ? -2.942  4.492   -30.727 1.00 19.79  ? 66  MET A N      1 
ATOM   1052  C CA     . MET A 1 66  ? -3.069  5.473   -31.807 1.00 19.89  ? 66  MET A CA     1 
ATOM   1053  C C      . MET A 1 66  ? -4.410  6.195   -31.759 1.00 16.60  ? 66  MET A C      1 
ATOM   1054  O O      . MET A 1 66  ? -4.973  6.571   -32.793 1.00 18.47  ? 66  MET A O      1 
ATOM   1055  C CB     . MET A 1 66  ? -2.904  4.796   -33.174 1.00 18.44  ? 66  MET A CB     1 
ATOM   1056  C CG     . MET A 1 66  ? -1.503  4.298   -33.469 1.00 26.93  ? 66  MET A CG     1 
ATOM   1057  S SD     . MET A 1 66  ? -0.273  5.604   -33.398 1.00 36.42  ? 66  MET A SD     1 
ATOM   1058  C CE     . MET A 1 66  ? -0.891  6.763   -34.618 1.00 34.83  ? 66  MET A CE     1 
ATOM   1059  H H      . MET A 1 66  ? -3.440  3.799   -30.834 1.00 23.75  ? 66  MET A H      1 
ATOM   1060  H HA     . MET A 1 66  ? -2.368  6.136   -31.722 1.00 23.87  ? 66  MET A HA     1 
ATOM   1061  H HB2    . MET A 1 66  ? -3.498  4.030   -33.211 1.00 22.13  ? 66  MET A HB2    1 
ATOM   1062  H HB3    . MET A 1 66  ? -3.142  5.423   -33.873 1.00 22.13  ? 66  MET A HB3    1 
ATOM   1063  H HG2    . MET A 1 66  ? -1.265  3.624   -32.814 1.00 32.31  ? 66  MET A HG2    1 
ATOM   1064  H HG3    . MET A 1 66  ? -1.484  3.916   -34.360 1.00 32.31  ? 66  MET A HG3    1 
ATOM   1065  H HE1    . MET A 1 66  ? -0.281  7.514   -34.668 1.00 41.80  ? 66  MET A HE1    1 
ATOM   1066  H HE2    . MET A 1 66  ? -0.944  6.319   -35.479 1.00 41.80  ? 66  MET A HE2    1 
ATOM   1067  H HE3    . MET A 1 66  ? -1.769  7.072   -34.348 1.00 41.80  ? 66  MET A HE3    1 
ATOM   1068  N N      . GLY A 1 67  ? -4.917  6.401   -30.555 1.00 13.94  ? 67  GLY A N      1 
ATOM   1069  C CA     . GLY A 1 67  ? -6.144  7.153   -30.391 1.00 17.29  ? 67  GLY A CA     1 
ATOM   1070  C C      . GLY A 1 67  ? -5.953  8.585   -30.843 1.00 19.68  ? 67  GLY A C      1 
ATOM   1071  O O      . GLY A 1 67  ? -5.103  9.292   -30.316 1.00 19.04  ? 67  GLY A O      1 
ATOM   1072  H H      . GLY A 1 67  ? -4.571  6.117   -29.821 1.00 16.73  ? 67  GLY A H      1 
ATOM   1073  H HA2    . GLY A 1 67  ? -6.851  6.749   -30.918 1.00 20.74  ? 67  GLY A HA2    1 
ATOM   1074  H HA3    . GLY A 1 67  ? -6.409  7.152   -29.458 1.00 20.74  ? 67  GLY A HA3    1 
ATOM   1075  N N      . ASP A 1 68  ? -6.728  8.979   -31.851 1.00 16.11  ? 68  ASP A N      1 
ATOM   1076  C CA     . ASP A 1 68  ? -6.819  10.360  -32.338 1.00 15.01  ? 68  ASP A CA     1 
ATOM   1077  C C      . ASP A 1 68  ? -8.045  10.975  -31.673 1.00 17.89  ? 68  ASP A C      1 
ATOM   1078  O O      . ASP A 1 68  ? -9.175  10.745  -32.102 1.00 17.55  ? 68  ASP A O      1 
ATOM   1079  C CB     . ASP A 1 68  ? -6.914  10.358  -33.875 1.00 16.22  ? 68  ASP A CB     1 
ATOM   1080  C CG     . ASP A 1 68  ? -7.026  11.749  -34.488 1.00 21.39  ? 68  ASP A CG     1 
ATOM   1081  O OD1    . ASP A 1 68  ? -7.138  12.766  -33.760 1.00 19.05  ? 68  ASP A OD1    1 
ATOM   1082  O OD2    . ASP A 1 68  ? -7.021  11.809  -35.742 1.00 18.69  ? 68  ASP A OD2    1 
ATOM   1083  H H      . ASP A 1 68  ? -7.233  8.440   -32.290 1.00 19.33  ? 68  ASP A H      1 
ATOM   1084  H HA     . ASP A 1 68  ? -6.032  10.861  -32.073 1.00 18.01  ? 68  ASP A HA     1 
ATOM   1085  H HB2    . ASP A 1 68  ? -6.117  9.940   -34.236 1.00 19.46  ? 68  ASP A HB2    1 
ATOM   1086  H HB3    . ASP A 1 68  ? -7.698  9.852   -34.140 1.00 19.46  ? 68  ASP A HB3    1 
ATOM   1087  N N      . GLU A 1 69  ? -7.822  11.705  -30.583 1.00 16.99  ? 69  GLU A N      1 
ATOM   1088  C CA     . GLU A 1 69  ? -8.912  12.103  -29.700 1.00 13.01  ? 69  GLU A CA     1 
ATOM   1089  C C      . GLU A 1 69  ? -9.559  13.425  -30.105 1.00 17.57  ? 69  GLU A C      1 
ATOM   1090  O O      . GLU A 1 69  ? -10.267 14.053  -29.306 1.00 18.91  ? 69  GLU A O      1 
ATOM   1091  C CB     . GLU A 1 69  ? -8.404  12.172  -28.257 1.00 15.63  ? 69  GLU A CB     1 
ATOM   1092  C CG     . GLU A 1 69  ? -7.901  10.814  -27.734 1.00 16.87  ? 69  GLU A CG     1 
ATOM   1093  C CD     . GLU A 1 69  ? -8.961  9.738   -27.786 1.00 18.58  ? 69  GLU A CD     1 
ATOM   1094  O OE1    . GLU A 1 69  ? -10.172 10.077  -27.736 1.00 16.95  ? 69  GLU A OE1    1 
ATOM   1095  O OE2    . GLU A 1 69  ? -8.584  8.547   -27.882 1.00 16.91  ? 69  GLU A OE2    1 
ATOM   1096  H H      . GLU A 1 69  ? -7.047  11.982  -30.333 1.00 20.39  ? 69  GLU A H      1 
ATOM   1097  H HA     . GLU A 1 69  ? -9.604  11.426  -29.739 1.00 15.61  ? 69  GLU A HA     1 
ATOM   1098  H HB2    . GLU A 1 69  ? -7.667  12.802  -28.212 1.00 18.76  ? 69  GLU A HB2    1 
ATOM   1099  H HB3    . GLU A 1 69  ? -9.126  12.465  -27.679 1.00 18.76  ? 69  GLU A HB3    1 
ATOM   1100  H HG2    . GLU A 1 69  ? -7.152  10.524  -28.277 1.00 20.25  ? 69  GLU A HG2    1 
ATOM   1101  H HG3    . GLU A 1 69  ? -7.622  10.915  -26.811 1.00 20.25  ? 69  GLU A HG3    1 
ATOM   1102  N N      . ALA A 1 70  ? -9.367  13.817  -31.363 1.00 15.91  ? 70  ALA A N      1 
ATOM   1103  C CA     . ALA A 1 70  ? -9.978  15.050  -31.866 1.00 17.75  ? 70  ALA A CA     1 
ATOM   1104  C C      . ALA A 1 70  ? -11.510 14.955  -31.863 1.00 17.41  ? 70  ALA A C      1 
ATOM   1105  O O      . ALA A 1 70  ? -12.101 13.886  -32.096 1.00 16.08  ? 70  ALA A O      1 
ATOM   1106  C CB     . ALA A 1 70  ? -9.461  15.367  -33.257 1.00 15.03  ? 70  ALA A CB     1 
ATOM   1107  H H      . ALA A 1 70  ? -8.893  13.395  -31.943 1.00 19.09  ? 70  ALA A H      1 
ATOM   1108  H HA     . ALA A 1 70  ? -9.726  15.783  -31.283 1.00 21.29  ? 70  ALA A HA     1 
ATOM   1109  H HB1    . ALA A 1 70  ? -9.878  16.185  -33.569 1.00 18.04  ? 70  ALA A HB1    1 
ATOM   1110  H HB2    . ALA A 1 70  ? -8.498  15.480  -33.217 1.00 18.04  ? 70  ALA A HB2    1 
ATOM   1111  H HB3    . ALA A 1 70  ? -9.684  14.634  -33.851 1.00 18.04  ? 70  ALA A HB3    1 
ATOM   1112  N N      . TYR A 1 71  ? -12.140 16.089  -31.590 1.00 16.43  ? 71  TYR A N      1 
ATOM   1113  C CA     . TYR A 1 71  ? -13.588 16.175  -31.467 1.00 21.02  ? 71  TYR A CA     1 
ATOM   1114  C C      . TYR A 1 71  ? -14.265 15.962  -32.817 1.00 18.69  ? 71  TYR A C      1 
ATOM   1115  O O      . TYR A 1 71  ? -15.396 15.478  -32.895 1.00 17.56  ? 71  TYR A O      1 
ATOM   1116  C CB     . TYR A 1 71  ? -13.981 17.534  -30.884 1.00 16.92  ? 71  TYR A CB     1 
ATOM   1117  C CG     . TYR A 1 71  ? -15.212 17.480  -30.017 1.00 19.33  ? 71  TYR A CG     1 
ATOM   1118  C CD1    . TYR A 1 71  ? -15.192 16.793  -28.805 1.00 21.56  ? 71  TYR A CD1    1 
ATOM   1119  C CD2    . TYR A 1 71  ? -16.389 18.116  -30.394 1.00 21.13  ? 71  TYR A CD2    1 
ATOM   1120  C CE1    . TYR A 1 71  ? -16.304 16.742  -27.998 1.00 23.51  ? 71  TYR A CE1    1 
ATOM   1121  C CE2    . TYR A 1 71  ? -17.522 18.063  -29.586 1.00 22.01  ? 71  TYR A CE2    1 
ATOM   1122  C CZ     . TYR A 1 71  ? -17.468 17.370  -28.390 1.00 21.53  ? 71  TYR A CZ     1 
ATOM   1123  O OH     . TYR A 1 71  ? -18.567 17.305  -27.570 1.00 28.38  ? 71  TYR A OH     1 
ATOM   1124  H H      . TYR A 1 71  ? -11.740 16.841  -31.469 1.00 19.71  ? 71  TYR A H      1 
ATOM   1125  H HA     . TYR A 1 71  ? -13.897 15.482  -30.863 1.00 25.23  ? 71  TYR A HA     1 
ATOM   1126  H HB2    . TYR A 1 71  ? -13.248 17.864  -30.342 1.00 20.30  ? 71  TYR A HB2    1 
ATOM   1127  H HB3    . TYR A 1 71  ? -14.157 18.149  -31.613 1.00 20.30  ? 71  TYR A HB3    1 
ATOM   1128  H HD1    . TYR A 1 71  ? -14.412 16.365  -28.535 1.00 25.87  ? 71  TYR A HD1    1 
ATOM   1129  H HD2    . TYR A 1 71  ? -16.422 18.579  -31.200 1.00 25.36  ? 71  TYR A HD2    1 
ATOM   1130  H HE1    . TYR A 1 71  ? -16.274 16.276  -27.194 1.00 28.22  ? 71  TYR A HE1    1 
ATOM   1131  H HE2    . TYR A 1 71  ? -18.306 18.490  -29.847 1.00 26.41  ? 71  TYR A HE2    1 
ATOM   1132  H HH     . TYR A 1 71  ? -19.098 17.924  -27.762 1.00 34.05  ? 71  TYR A HH     1 
ATOM   1133  N N      . ALA A 1 72  ? -13.551 16.325  -33.876 1.00 16.44  ? 72  ALA A N      1 
ATOM   1134  C CA     . ALA A 1 72  ? -14.032 16.147  -35.242 1.00 21.90  ? 72  ALA A CA     1 
ATOM   1135  C C      . ALA A 1 72  ? -12.876 15.759  -36.134 1.00 16.84  ? 72  ALA A C      1 
ATOM   1136  O O      . ALA A 1 72  ? -11.741 16.191  -35.910 1.00 16.65  ? 72  ALA A O      1 
ATOM   1137  C CB     . ALA A 1 72  ? -14.685 17.423  -35.750 1.00 21.65  ? 72  ALA A CB     1 
ATOM   1138  H H      . ALA A 1 72  ? -12.771 16.684  -33.831 1.00 19.73  ? 72  ALA A H      1 
ATOM   1139  H HA     . ALA A 1 72  ? -14.689 15.434  -35.269 1.00 26.28  ? 72  ALA A HA     1 
ATOM   1140  H HB1    . ALA A 1 72  ? -14.995 17.279  -36.658 1.00 25.98  ? 72  ALA A HB1    1 
ATOM   1141  H HB2    . ALA A 1 72  ? -15.434 17.644  -35.175 1.00 25.98  ? 72  ALA A HB2    1 
ATOM   1142  H HB3    . ALA A 1 72  ? -14.032 18.140  -35.733 1.00 25.98  ? 72  ALA A HB3    1 
ATOM   1143  N N      . GLY A 1 73  ? -13.160 14.949  -37.152 1.00 15.73  ? 73  GLY A N      1 
ATOM   1144  C CA     . GLY A 1 73  ? -12.161 14.589  -38.130 1.00 15.17  ? 73  GLY A CA     1 
ATOM   1145  C C      . GLY A 1 73  ? -11.138 13.571  -37.646 1.00 14.76  ? 73  GLY A C      1 
ATOM   1146  O O      . GLY A 1 73  ? -10.067 13.445  -38.233 1.00 17.79  ? 73  GLY A O      1 
ATOM   1147  H H      . GLY A 1 73  ? -13.932 14.597  -37.292 1.00 18.88  ? 73  GLY A H      1 
ATOM   1148  H HA2    . GLY A 1 73  ? -12.603 14.221  -38.911 1.00 18.21  ? 73  GLY A HA2    1 
ATOM   1149  H HA3    . GLY A 1 73  ? -11.683 15.388  -38.403 1.00 18.21  ? 73  GLY A HA3    1 
ATOM   1150  N N      . SER A 1 74  ? -11.454 12.833  -36.585 1.00 15.14  ? 74  SER A N      1 
ATOM   1151  C CA     . SER A 1 74  ? -10.530 11.810  -36.095 1.00 15.12  ? 74  SER A CA     1 
ATOM   1152  C C      . SER A 1 74  ? -10.256 10.729  -37.135 1.00 14.35  ? 74  SER A C      1 
ATOM   1153  O O      . SER A 1 74  ? -11.186 10.198  -37.748 1.00 16.78  ? 74  SER A O      1 
ATOM   1154  C CB     . SER A 1 74  ? -11.074 11.139  -34.829 1.00 15.86  ? 74  SER A CB     1 
ATOM   1155  O OG     . SER A 1 74  ? -10.220 10.063  -34.453 1.00 17.12  ? 74  SER A OG     1 
ATOM   1156  H H      . SER A 1 74  ? -12.185 12.901  -36.136 1.00 18.16  ? 74  SER A H      1 
ATOM   1157  H HA     . SER A 1 74  ? -9.685  12.231  -35.871 1.00 18.14  ? 74  SER A HA     1 
ATOM   1158  H HB2    . SER A 1 74  ? -11.104 11.790  -34.110 1.00 19.03  ? 74  SER A HB2    1 
ATOM   1159  H HB3    . SER A 1 74  ? -11.963 10.794  -35.007 1.00 19.03  ? 74  SER A HB3    1 
ATOM   1160  H HG     . SER A 1 74  ? -10.514 9.692   -33.759 1.00 20.55  ? 74  SER A HG     1 
ATOM   1161  N N      . GLU A 1 75  ? -8.982  10.385  -37.303 1.00 15.87  ? 75  GLU A N      1 
ATOM   1162  C CA     . GLU A 1 75  ? -8.591  9.257   -38.135 1.00 18.43  ? 75  GLU A CA     1 
ATOM   1163  C C      . GLU A 1 75  ? -9.330  7.981   -37.724 1.00 16.05  ? 75  GLU A C      1 
ATOM   1164  O O      . GLU A 1 75  ? -9.649  7.139   -38.576 1.00 16.96  ? 75  GLU A O      1 
ATOM   1165  C CB     . GLU A 1 75  ? -7.079  9.021   -38.052 1.00 24.86  ? 75  GLU A CB     1 
ATOM   1166  C CG     . GLU A 1 75  ? -6.249  9.974   -38.880 1.00 26.29  ? 75  GLU A CG     1 
ATOM   1167  C CD     . GLU A 1 75  ? -6.475  9.771   -40.371 1.00 36.74  ? 75  GLU A CD     1 
ATOM   1168  O OE1    . GLU A 1 75  ? -7.176  10.601  -40.987 1.00 26.09  ? 75  GLU A OE1    1 
ATOM   1169  O OE2    . GLU A 1 75  ? -5.964  8.771   -40.921 1.00 35.73  ? 75  GLU A OE2    1 
ATOM   1170  H H      . GLU A 1 75  ? -8.319  10.796  -36.940 1.00 19.04  ? 75  GLU A H      1 
ATOM   1171  H HA     . GLU A 1 75  ? -8.819  9.451   -39.058 1.00 22.11  ? 75  GLU A HA     1 
ATOM   1172  H HB2    . GLU A 1 75  ? -6.801  9.116   -37.128 1.00 29.83  ? 75  GLU A HB2    1 
ATOM   1173  H HB3    . GLU A 1 75  ? -6.888  8.121   -38.360 1.00 29.83  ? 75  GLU A HB3    1 
ATOM   1174  H HG2    . GLU A 1 75  ? -6.492  10.886  -38.657 1.00 31.55  ? 75  GLU A HG2    1 
ATOM   1175  H HG3    . GLU A 1 75  ? -5.309  9.823   -38.693 1.00 31.55  ? 75  GLU A HG3    1 
ATOM   1176  N N      . ASN A 1 76  ? -9.582  7.834   -36.424 1.00 13.98  ? 76  ASN A N      1 
ATOM   1177  C CA     . ASN A 1 76  ? -10.273 6.644   -35.909 1.00 16.92  ? 76  ASN A CA     1 
ATOM   1178  C C      . ASN A 1 76  ? -11.722 6.594   -36.375 1.00 17.95  ? 76  ASN A C      1 
ATOM   1179  O O      . ASN A 1 76  ? -12.247 5.520   -36.684 1.00 14.30  ? 76  ASN A O      1 
ATOM   1180  C CB     . ASN A 1 76  ? -10.244 6.597   -34.381 1.00 14.45  ? 76  ASN A CB     1 
ATOM   1181  C CG     . ASN A 1 76  ? -8.870  6.827   -33.811 1.00 16.57  ? 76  ASN A CG     1 
ATOM   1182  O OD1    . ASN A 1 76  ? -8.712  7.646   -32.922 1.00 16.88  ? 76  ASN A OD1    1 
ATOM   1183  N ND2    . ASN A 1 76  ? -7.872  6.090   -34.302 1.00 15.55  ? 76  ASN A ND2    1 
ATOM   1184  H H      . ASN A 1 76  ? -9.366  8.406   -35.819 1.00 16.77  ? 76  ASN A H      1 
ATOM   1185  H HA     . ASN A 1 76  ? -9.824  5.851   -36.241 1.00 20.30  ? 76  ASN A HA     1 
ATOM   1186  H HB2    . ASN A 1 76  ? -10.832 7.285   -34.033 1.00 17.34  ? 76  ASN A HB2    1 
ATOM   1187  H HB3    . ASN A 1 76  ? -10.547 5.723   -34.089 1.00 17.34  ? 76  ASN A HB3    1 
ATOM   1188  H HD21   . ASN A 1 76  ? -7.073  6.194   -34.002 1.00 18.66  ? 76  ASN A HD21   1 
ATOM   1189  H HD22   . ASN A 1 76  ? -8.028  5.511   -34.919 1.00 18.66  ? 76  ASN A HD22   1 
ATOM   1190  N N      . PHE A 1 77  ? -12.376 7.755   -36.415 1.00 15.44  ? 77  PHE A N      1 
ATOM   1191  C CA     . PHE A 1 77  ? -13.745 7.811   -36.926 1.00 16.51  ? 77  PHE A CA     1 
ATOM   1192  C C      . PHE A 1 77  ? -13.776 7.366   -38.397 1.00 15.59  ? 77  PHE A C      1 
ATOM   1193  O O      . PHE A 1 77  ? -14.613 6.552   -38.785 1.00 17.31  ? 77  PHE A O      1 
ATOM   1194  C CB     . PHE A 1 77  ? -14.359 9.212   -36.800 1.00 18.44  ? 77  PHE A CB     1 
ATOM   1195  C CG     . PHE A 1 77  ? -15.633 9.363   -37.592 1.00 17.98  ? 77  PHE A CG     1 
ATOM   1196  C CD1    . PHE A 1 77  ? -16.837 8.917   -37.070 1.00 23.35  ? 77  PHE A CD1    1 
ATOM   1197  C CD2    . PHE A 1 77  ? -15.618 9.902   -38.869 1.00 20.97  ? 77  PHE A CD2    1 
ATOM   1198  C CE1    . PHE A 1 77  ? -18.016 9.014   -37.798 1.00 24.76  ? 77  PHE A CE1    1 
ATOM   1199  C CE2    . PHE A 1 77  ? -16.795 10.001  -39.610 1.00 26.36  ? 77  PHE A CE2    1 
ATOM   1200  C CZ     . PHE A 1 77  ? -17.993 9.558   -39.068 1.00 24.99  ? 77  PHE A CZ     1 
ATOM   1201  H H      . PHE A 1 77  ? -12.057 8.511   -36.157 1.00 18.53  ? 77  PHE A H      1 
ATOM   1202  H HA     . PHE A 1 77  ? -14.296 7.197   -36.416 1.00 19.81  ? 77  PHE A HA     1 
ATOM   1203  H HB2    . PHE A 1 77  ? -14.563 9.385   -35.868 1.00 22.13  ? 77  PHE A HB2    1 
ATOM   1204  H HB3    . PHE A 1 77  ? -13.723 9.867   -37.128 1.00 22.13  ? 77  PHE A HB3    1 
ATOM   1205  H HD1    . PHE A 1 77  ? -16.856 8.544   -36.218 1.00 28.02  ? 77  PHE A HD1    1 
ATOM   1206  H HD2    . PHE A 1 77  ? -14.815 10.194  -39.237 1.00 25.17  ? 77  PHE A HD2    1 
ATOM   1207  H HE1    . PHE A 1 77  ? -18.818 8.718   -37.431 1.00 29.71  ? 77  PHE A HE1    1 
ATOM   1208  H HE2    . PHE A 1 77  ? -16.779 10.372  -40.463 1.00 31.63  ? 77  PHE A HE2    1 
ATOM   1209  H HZ     . PHE A 1 77  ? -18.781 9.634   -39.556 1.00 29.99  ? 77  PHE A HZ     1 
ATOM   1210  N N      . PHE A 1 78  ? -12.860 7.881   -39.208 1.00 18.69  ? 78  PHE A N      1 
ATOM   1211  C CA     . PHE A 1 78  ? -12.844 7.538   -40.628 1.00 18.40  ? 78  PHE A CA     1 
ATOM   1212  C C      . PHE A 1 78  ? -12.557 6.045   -40.829 1.00 17.09  ? 78  PHE A C      1 
ATOM   1213  O O      . PHE A 1 78  ? -13.135 5.408   -41.716 1.00 18.77  ? 78  PHE A O      1 
ATOM   1214  C CB     . PHE A 1 78  ? -11.819 8.394   -41.384 1.00 17.79  ? 78  PHE A CB     1 
ATOM   1215  C CG     . PHE A 1 78  ? -12.170 9.858   -41.421 1.00 20.74  ? 78  PHE A CG     1 
ATOM   1216  C CD1    . PHE A 1 78  ? -13.411 10.272  -41.880 1.00 21.53  ? 78  PHE A CD1    1 
ATOM   1217  C CD2    . PHE A 1 78  ? -11.269 10.818  -40.978 1.00 21.44  ? 78  PHE A CD2    1 
ATOM   1218  C CE1    . PHE A 1 78  ? -13.747 11.614  -41.910 1.00 24.53  ? 78  PHE A CE1    1 
ATOM   1219  C CE2    . PHE A 1 78  ? -11.601 12.169  -41.006 1.00 22.16  ? 78  PHE A CE2    1 
ATOM   1220  C CZ     . PHE A 1 78  ? -12.838 12.563  -41.469 1.00 21.50  ? 78  PHE A CZ     1 
ATOM   1221  H H      . PHE A 1 78  ? -12.241 8.427   -38.966 1.00 22.43  ? 78  PHE A H      1 
ATOM   1222  H HA     . PHE A 1 78  ? -13.720 7.719   -41.002 1.00 22.08  ? 78  PHE A HA     1 
ATOM   1223  H HB2    . PHE A 1 78  ? -10.956 8.306   -40.950 1.00 21.35  ? 78  PHE A HB2    1 
ATOM   1224  H HB3    . PHE A 1 78  ? -11.761 8.079   -42.299 1.00 21.35  ? 78  PHE A HB3    1 
ATOM   1225  H HD1    . PHE A 1 78  ? -14.025 9.639   -42.176 1.00 25.84  ? 78  PHE A HD1    1 
ATOM   1226  H HD2    . PHE A 1 78  ? -10.434 10.556  -40.664 1.00 25.73  ? 78  PHE A HD2    1 
ATOM   1227  H HE1    . PHE A 1 78  ? -14.582 11.879  -42.224 1.00 29.44  ? 78  PHE A HE1    1 
ATOM   1228  H HE2    . PHE A 1 78  ? -10.990 12.805  -40.711 1.00 26.59  ? 78  PHE A HE2    1 
ATOM   1229  H HZ     . PHE A 1 78  ? -13.061 13.466  -41.490 1.00 25.80  ? 78  PHE A HZ     1 
ATOM   1230  N N      . HIS A 1 79  ? -11.693 5.480   -39.991 1.00 15.55  ? 79  HIS A N      1 
ATOM   1231  C CA     . HIS A 1 79  ? -11.418 4.042   -40.045 1.00 17.85  ? 79  HIS A CA     1 
ATOM   1232  C C      . HIS A 1 79  ? -12.689 3.232   -39.760 1.00 16.48  ? 79  HIS A C      1 
ATOM   1233  O O      . HIS A 1 79  ? -13.017 2.287   -40.482 1.00 16.55  ? 79  HIS A O      1 
ATOM   1234  C CB     . HIS A 1 79  ? -10.332 3.646   -39.040 1.00 21.60  ? 79  HIS A CB     1 
ATOM   1235  C CG     . HIS A 1 79  ? -8.967  4.150   -39.388 1.00 27.44  ? 79  HIS A CG     1 
ATOM   1236  N ND1    . HIS A 1 79  ? -7.963  4.291   -38.449 1.00 34.09  ? 79  HIS A ND1    1 
ATOM   1237  C CD2    . HIS A 1 79  ? -8.429  4.528   -40.571 1.00 32.67  ? 79  HIS A CD2    1 
ATOM   1238  C CE1    . HIS A 1 79  ? -6.872  4.744   -39.040 1.00 35.94  ? 79  HIS A CE1    1 
ATOM   1239  N NE2    . HIS A 1 79  ? -7.125  4.893   -40.329 1.00 36.79  ? 79  HIS A NE2    1 
ATOM   1240  H H      . HIS A 1 79  ? -11.254 5.902   -39.384 1.00 18.66  ? 79  HIS A H      1 
ATOM   1241  H HA     . HIS A 1 79  ? -11.107 3.811   -40.934 1.00 21.42  ? 79  HIS A HA     1 
ATOM   1242  H HB2    . HIS A 1 79  ? -10.567 4.006   -38.170 1.00 25.93  ? 79  HIS A HB2    1 
ATOM   1243  H HB3    . HIS A 1 79  ? -10.288 2.678   -38.993 1.00 25.93  ? 79  HIS A HB3    1 
ATOM   1244  H HD1    . HIS A 1 79  ? -8.038  4.116   -37.612 1.00 40.91  ? 79  HIS A HD1    1 
ATOM   1245  H HD2    . HIS A 1 79  ? -8.864  4.541   -41.391 1.00 39.20  ? 79  HIS A HD2    1 
ATOM   1246  H HE1    . HIS A 1 79  ? -6.061  4.923   -38.622 1.00 43.13  ? 79  HIS A HE1    1 
ATOM   1247  N N      . LEU A 1 80  ? -13.383 3.592   -38.691 1.00 17.54  ? 80  LEU A N      1 
ATOM   1248  C CA     . LEU A 1 80  ? -14.618 2.910   -38.319 1.00 16.31  ? 80  LEU A CA     1 
ATOM   1249  C C      . LEU A 1 80  ? -15.638 3.051   -39.438 1.00 18.24  ? 80  LEU A C      1 
ATOM   1250  O O      . LEU A 1 80  ? -16.263 2.075   -39.859 1.00 15.42  ? 80  LEU A O      1 
ATOM   1251  C CB     . LEU A 1 80  ? -15.173 3.476   -37.011 1.00 15.41  ? 80  LEU A CB     1 
ATOM   1252  C CG     . LEU A 1 80  ? -16.533 2.948   -36.555 1.00 13.65  ? 80  LEU A CG     1 
ATOM   1253  C CD1    . LEU A 1 80  ? -16.445 1.444   -36.288 1.00 15.43  ? 80  LEU A CD1    1 
ATOM   1254  C CD2    . LEU A 1 80  ? -16.989 3.679   -35.311 1.00 20.04  ? 80  LEU A CD2    1 
ATOM   1255  H H      . LEU A 1 80  ? -13.161 4.231   -38.160 1.00 21.04  ? 80  LEU A H      1 
ATOM   1256  H HA     . LEU A 1 80  ? -14.437 1.966   -38.191 1.00 19.58  ? 80  LEU A HA     1 
ATOM   1257  H HB2    . LEU A 1 80  ? -14.538 3.281   -36.304 1.00 18.49  ? 80  LEU A HB2    1 
ATOM   1258  H HB3    . LEU A 1 80  ? -15.257 4.437   -37.109 1.00 18.49  ? 80  LEU A HB3    1 
ATOM   1259  H HG     . LEU A 1 80  ? -17.191 3.097   -37.252 1.00 16.38  ? 80  LEU A HG     1 
ATOM   1260  H HD11   . LEU A 1 80  ? -17.293 1.137   -35.932 1.00 18.51  ? 80  LEU A HD11   1 
ATOM   1261  H HD12   . LEU A 1 80  ? -16.251 0.986   -37.120 1.00 18.51  ? 80  LEU A HD12   1 
ATOM   1262  H HD13   . LEU A 1 80  ? -15.737 1.279   -35.645 1.00 18.51  ? 80  LEU A HD13   1 
ATOM   1263  H HD21   . LEU A 1 80  ? -17.852 3.330   -35.039 1.00 24.05  ? 80  LEU A HD21   1 
ATOM   1264  H HD22   . LEU A 1 80  ? -16.337 3.539   -34.606 1.00 24.05  ? 80  LEU A HD22   1 
ATOM   1265  H HD23   . LEU A 1 80  ? -17.063 4.625   -35.511 1.00 24.05  ? 80  LEU A HD23   1 
ATOM   1266  N N      . GLU A 1 81  ? -15.790 4.275   -39.928 1.00 19.30  ? 81  GLU A N      1 
ATOM   1267  C CA     . GLU A 1 81  ? -16.777 4.557   -40.967 1.00 21.24  ? 81  GLU A CA     1 
ATOM   1268  C C      . GLU A 1 81  ? -16.574 3.701   -42.222 1.00 18.35  ? 81  GLU A C      1 
ATOM   1269  O O      . GLU A 1 81  ? -17.514 3.074   -42.719 1.00 19.62  ? 81  GLU A O      1 
ATOM   1270  C CB     . GLU A 1 81  ? -16.730 6.039   -41.335 1.00 21.68  ? 81  GLU A CB     1 
ATOM   1271  C CG     . GLU A 1 81  ? -17.767 6.460   -42.367 1.00 27.91  ? 81  GLU A CG     1 
ATOM   1272  C CD     . GLU A 1 81  ? -17.695 7.946   -42.678 1.00 30.70  ? 81  GLU A CD     1 
ATOM   1273  O OE1    . GLU A 1 81  ? -16.607 8.420   -43.061 1.00 24.78  ? 81  GLU A OE1    1 
ATOM   1274  O OE2    . GLU A 1 81  ? -18.719 8.641   -42.523 1.00 27.22  ? 81  GLU A OE2    1 
ATOM   1275  H H      . GLU A 1 81  ? -15.335 4.961   -39.677 1.00 23.16  ? 81  GLU A H      1 
ATOM   1276  H HA     . GLU A 1 81  ? -17.657 4.362   -40.616 1.00 25.49  ? 81  GLU A HA     1 
ATOM   1277  H HB2    . GLU A 1 81  ? -16.882 6.563   -40.533 1.00 26.01  ? 81  GLU A HB2    1 
ATOM   1278  H HB3    . GLU A 1 81  ? -15.853 6.242   -41.698 1.00 26.01  ? 81  GLU A HB3    1 
ATOM   1279  H HG2    . GLU A 1 81  ? -17.614 5.975   -43.193 1.00 33.49  ? 81  GLU A HG2    1 
ATOM   1280  H HG3    . GLU A 1 81  ? -18.653 6.266   -42.026 1.00 33.49  ? 81  GLU A HG3    1 
ATOM   1281  N N      . ARG A 1 82  ? -15.355 3.645   -42.741 1.00 18.40  ? 82  ARG A N      1 
ATOM   1282  C CA     . ARG A 1 82  ? -15.165 2.904   -43.980 1.00 21.87  ? 82  ARG A CA     1 
ATOM   1283  C C      . ARG A 1 82  ? -15.149 1.396   -43.746 1.00 19.84  ? 82  ARG A C      1 
ATOM   1284  O O      . ARG A 1 82  ? -15.548 0.639   -44.626 1.00 18.92  ? 82  ARG A O      1 
ATOM   1285  C CB     . ARG A 1 82  ? -13.904 3.354   -44.700 1.00 29.17  ? 82  ARG A CB     1 
ATOM   1286  C CG     . ARG A 1 82  ? -12.614 2.977   -44.088 1.00 33.57  ? 82  ARG A CG     1 
ATOM   1287  C CD     . ARG A 1 82  ? -11.513 3.448   -45.030 1.00 50.56  ? 82  ARG A CD     1 
ATOM   1288  N NE     . ARG A 1 82  ? -10.173 3.187   -44.517 1.00 59.37  ? 82  ARG A NE     1 
ATOM   1289  C CZ     . ARG A 1 82  ? -9.436  4.064   -43.840 1.00 54.82  ? 82  ARG A CZ     1 
ATOM   1290  N NH1    . ARG A 1 82  ? -9.892  5.291   -43.572 1.00 45.42  ? 82  ARG A NH1    1 
ATOM   1291  N NH2    . ARG A 1 82  ? -8.227  3.705   -43.434 1.00 65.38  ? 82  ARG A NH2    1 
ATOM   1292  H H      . ARG A 1 82  ? -14.649 4.010   -42.413 1.00 22.08  ? 82  ARG A H      1 
ATOM   1293  H HA     . ARG A 1 82  ? -15.909 3.096   -44.572 1.00 26.25  ? 82  ARG A HA     1 
ATOM   1294  H HB2    . ARG A 1 82  ? -13.917 2.978   -45.594 1.00 35.00  ? 82  ARG A HB2    1 
ATOM   1295  H HB3    . ARG A 1 82  ? -13.920 4.322   -44.760 1.00 35.00  ? 82  ARG A HB3    1 
ATOM   1296  H HG2    . ARG A 1 82  ? -12.509 3.419   -43.231 1.00 40.28  ? 82  ARG A HG2    1 
ATOM   1297  H HG3    . ARG A 1 82  ? -12.554 2.014   -43.994 1.00 40.28  ? 82  ARG A HG3    1 
ATOM   1298  H HD2    . ARG A 1 82  ? -11.602 2.973   -45.871 1.00 60.67  ? 82  ARG A HD2    1 
ATOM   1299  H HD3    . ARG A 1 82  ? -11.609 4.400   -45.183 1.00 60.67  ? 82  ARG A HD3    1 
ATOM   1300  H HE     . ARG A 1 82  ? -9.835  2.410   -44.663 1.00 71.24  ? 82  ARG A HE     1 
ATOM   1301  H HH11   . ARG A 1 82  ? -10.674 5.532   -43.833 1.00 54.51  ? 82  ARG A HH11   1 
ATOM   1302  H HH12   . ARG A 1 82  ? -9.400  5.843   -43.133 1.00 54.51  ? 82  ARG A HH12   1 
ATOM   1303  H HH21   . ARG A 1 82  ? -7.933  2.916   -43.607 1.00 78.46  ? 82  ARG A HH21   1 
ATOM   1304  H HH22   . ARG A 1 82  ? -7.737  4.259   -42.996 1.00 78.46  ? 82  ARG A HH22   1 
ATOM   1305  N N      . THR A 1 83  ? -14.723 0.960   -42.561 1.00 17.60  ? 83  THR A N      1 
ATOM   1306  C CA     . THR A 1 83  ? -14.824 -0.453  -42.198 1.00 18.29  ? 83  THR A CA     1 
ATOM   1307  C C      . THR A 1 83  ? -16.280 -0.920  -42.181 1.00 19.04  ? 83  THR A C      1 
ATOM   1308  O O      . THR A 1 83  ? -16.606 -1.971  -42.743 1.00 17.19  ? 83  THR A O      1 
ATOM   1309  C CB     . THR A 1 83  ? -14.184 -0.736  -40.819 1.00 18.89  ? 83  THR A CB     1 
ATOM   1310  O OG1    . THR A 1 83  ? -12.774 -0.478  -40.876 1.00 19.15  ? 83  THR A OG1    1 
ATOM   1311  C CG2    . THR A 1 83  ? -14.410 -2.197  -40.402 1.00 16.92  ? 83  THR A CG2    1 
ATOM   1312  H H      . THR A 1 83  ? -14.374 1.458   -41.953 1.00 21.12  ? 83  THR A H      1 
ATOM   1313  H HA     . THR A 1 83  ? -14.350 -0.981  -42.860 1.00 21.95  ? 83  THR A HA     1 
ATOM   1314  H HB     . THR A 1 83  ? -14.590 -0.161  -40.151 1.00 22.66  ? 83  THR A HB     1 
ATOM   1315  H HG1    . THR A 1 83  ? -12.637 0.325   -41.082 1.00 22.98  ? 83  THR A HG1    1 
ATOM   1316  H HG21   . THR A 1 83  ? -13.784 -2.440  -39.703 1.00 20.30  ? 83  THR A HG21   1 
ATOM   1317  H HG22   . THR A 1 83  ? -15.313 -2.314  -40.069 1.00 20.30  ? 83  THR A HG22   1 
ATOM   1318  H HG23   . THR A 1 83  ? -14.274 -2.783  -41.163 1.00 20.30  ? 83  THR A HG23   1 
ATOM   1319  N N      . VAL A 1 84  ? -17.161 -0.157  -41.539 1.00 14.83  ? 84  VAL A N      1 
ATOM   1320  C CA     . VAL A 1 84  ? -18.559 -0.561  -41.447 1.00 19.34  ? 84  VAL A CA     1 
ATOM   1321  C C      . VAL A 1 84  ? -19.219 -0.445  -42.830 1.00 21.46  ? 84  VAL A C      1 
ATOM   1322  O O      . VAL A 1 84  ? -19.969 -1.333  -43.239 1.00 18.91  ? 84  VAL A O      1 
ATOM   1323  C CB     . VAL A 1 84  ? -19.312 0.263   -40.386 1.00 17.46  ? 84  VAL A CB     1 
ATOM   1324  C CG1    . VAL A 1 84  ? -20.815 -0.028  -40.396 1.00 19.49  ? 84  VAL A CG1    1 
ATOM   1325  C CG2    . VAL A 1 84  ? -18.730 -0.042  -39.012 1.00 20.38  ? 84  VAL A CG2    1 
ATOM   1326  H H      . VAL A 1 84  ? -16.977 0.589   -41.153 1.00 17.80  ? 84  VAL A H      1 
ATOM   1327  H HA     . VAL A 1 84  ? -18.598 -1.492  -41.178 1.00 23.20  ? 84  VAL A HA     1 
ATOM   1328  H HB     . VAL A 1 84  ? -19.185 1.208   -40.566 1.00 20.95  ? 84  VAL A HB     1 
ATOM   1329  H HG11   . VAL A 1 84  ? -21.213 0.349   -39.596 1.00 23.39  ? 84  VAL A HG11   1 
ATOM   1330  H HG12   . VAL A 1 84  ? -21.212 0.376   -41.183 1.00 23.39  ? 84  VAL A HG12   1 
ATOM   1331  H HG13   . VAL A 1 84  ? -20.950 -0.988  -40.410 1.00 23.39  ? 84  VAL A HG13   1 
ATOM   1332  H HG21   . VAL A 1 84  ? -19.223 0.456   -38.341 1.00 24.46  ? 84  VAL A HG21   1 
ATOM   1333  H HG22   . VAL A 1 84  ? -18.810 -0.994  -38.841 1.00 24.46  ? 84  VAL A HG22   1 
ATOM   1334  H HG23   . VAL A 1 84  ? -17.796 0.219   -38.998 1.00 24.46  ? 84  VAL A HG23   1 
ATOM   1335  N N      . GLN A 1 85  ? -18.901 0.612   -43.574 1.00 18.85  ? 85  GLN A N      1 
ATOM   1336  C CA     . GLN A 1 85  ? -19.415 0.745   -44.941 1.00 18.65  ? 85  GLN A CA     1 
ATOM   1337  C C      . GLN A 1 85  ? -19.004 -0.449  -45.806 1.00 21.42  ? 85  GLN A C      1 
ATOM   1338  O O      . GLN A 1 85  ? -19.815 -0.983  -46.561 1.00 22.34  ? 85  GLN A O      1 
ATOM   1339  C CB     . GLN A 1 85  ? -18.932 2.055   -45.577 1.00 22.56  ? 85  GLN A CB     1 
ATOM   1340  C CG     . GLN A 1 85  ? -19.672 3.286   -45.058 1.00 28.47  ? 85  GLN A CG     1 
ATOM   1341  C CD     . GLN A 1 85  ? -19.005 4.600   -45.440 1.00 34.63  ? 85  GLN A CD     1 
ATOM   1342  O OE1    . GLN A 1 85  ? -17.859 4.622   -45.893 1.00 30.90  ? 85  GLN A OE1    1 
ATOM   1343  N NE2    . GLN A 1 85  ? -19.728 5.707   -45.261 1.00 32.93  ? 85  GLN A NE2    1 
ATOM   1344  H H      . GLN A 1 85  ? -18.396 1.259   -43.318 1.00 22.62  ? 85  GLN A H      1 
ATOM   1345  H HA     . GLN A 1 85  ? -20.384 0.770   -44.910 1.00 22.38  ? 85  GLN A HA     1 
ATOM   1346  H HB2    . GLN A 1 85  ? -17.989 2.166   -45.381 1.00 27.07  ? 85  GLN A HB2    1 
ATOM   1347  H HB3    . GLN A 1 85  ? -19.067 2.008   -46.536 1.00 27.07  ? 85  GLN A HB3    1 
ATOM   1348  H HG2    . GLN A 1 85  ? -20.569 3.291   -45.427 1.00 34.16  ? 85  GLN A HG2    1 
ATOM   1349  H HG3    . GLN A 1 85  ? -19.714 3.243   -44.090 1.00 34.16  ? 85  GLN A HG3    1 
ATOM   1350  H HE21   . GLN A 1 85  ? -20.526 5.653   -44.945 1.00 39.52  ? 85  GLN A HE21   1 
ATOM   1351  H HE22   . GLN A 1 85  ? -19.396 6.475   -45.462 1.00 39.52  ? 85  GLN A HE22   1 
ATOM   1352  N N      . GLU A 1 86  ? -17.752 -0.878  -45.689 1.00 21.23  ? 86  GLU A N      1 
ATOM   1353  C CA     . GLU A 1 86  ? -17.256 -1.994  -46.484 1.00 22.53  ? 86  GLU A CA     1 
ATOM   1354  C C      . GLU A 1 86  ? -17.891 -3.325  -46.076 1.00 20.21  ? 86  GLU A C      1 
ATOM   1355  O O      . GLU A 1 86  ? -18.327 -4.103  -46.934 1.00 21.76  ? 86  GLU A O      1 
ATOM   1356  C CB     . GLU A 1 86  ? -15.731 -2.083  -46.366 1.00 20.62  ? 86  GLU A CB     1 
ATOM   1357  C CG     . GLU A 1 86  ? -15.111 -3.289  -47.068 1.00 30.64  ? 86  GLU A CG     1 
ATOM   1358  C CD     . GLU A 1 86  ? -13.631 -3.460  -46.756 1.00 37.96  ? 86  GLU A CD     1 
ATOM   1359  O OE1    . GLU A 1 86  ? -12.966 -2.464  -46.390 1.00 35.43  ? 86  GLU A OE1    1 
ATOM   1360  O OE2    . GLU A 1 86  ? -13.137 -4.601  -46.869 1.00 37.85  ? 86  GLU A OE2    1 
ATOM   1361  H H      . GLU A 1 86  ? -17.169 -0.539  -45.155 1.00 25.47  ? 86  GLU A H      1 
ATOM   1362  H HA     . GLU A 1 86  ? -17.473 -1.835  -47.416 1.00 27.03  ? 86  GLU A HA     1 
ATOM   1363  H HB2    . GLU A 1 86  ? -15.343 -1.284  -46.756 1.00 24.74  ? 86  GLU A HB2    1 
ATOM   1364  H HB3    . GLU A 1 86  ? -15.495 -2.136  -45.427 1.00 24.74  ? 86  GLU A HB3    1 
ATOM   1365  H HG2    . GLU A 1 86  ? -15.559 -4.100  -46.785 1.00 36.76  ? 86  GLU A HG2    1 
ATOM   1366  H HG3    . GLU A 1 86  ? -15.203 -3.177  -48.027 1.00 36.76  ? 86  GLU A HG3    1 
ATOM   1367  N N      . LEU A 1 87  ? -17.948 -3.598  -44.774 1.00 18.66  ? 87  LEU A N      1 
ATOM   1368  C CA     . LEU A 1 87  ? -18.351 -4.922  -44.303 1.00 20.18  ? 87  LEU A CA     1 
ATOM   1369  C C      . LEU A 1 87  ? -19.860 -5.097  -44.158 1.00 19.03  ? 87  LEU A C      1 
ATOM   1370  O O      . LEU A 1 87  ? -20.365 -6.184  -44.408 1.00 23.70  ? 87  LEU A O      1 
ATOM   1371  C CB     . LEU A 1 87  ? -17.664 -5.236  -42.970 1.00 22.28  ? 87  LEU A CB     1 
ATOM   1372  C CG     . LEU A 1 87  ? -16.133 -5.314  -43.037 1.00 22.14  ? 87  LEU A CG     1 
ATOM   1373  C CD1    . LEU A 1 87  ? -15.537 -5.669  -41.677 1.00 21.59  ? 87  LEU A CD1    1 
ATOM   1374  C CD2    . LEU A 1 87  ? -15.667 -6.312  -44.076 1.00 26.74  ? 87  LEU A CD2    1 
ATOM   1375  H H      . LEU A 1 87  ? -17.760 -3.040  -44.148 1.00 22.40  ? 87  LEU A H      1 
ATOM   1376  H HA     . LEU A 1 87  ? -18.052 -5.580  -44.948 1.00 24.22  ? 87  LEU A HA     1 
ATOM   1377  H HB2    . LEU A 1 87  ? -17.894 -4.542  -42.333 1.00 26.74  ? 87  LEU A HB2    1 
ATOM   1378  H HB3    . LEU A 1 87  ? -17.987 -6.093  -42.650 1.00 26.74  ? 87  LEU A HB3    1 
ATOM   1379  H HG     . LEU A 1 87  ? -15.789 -4.443  -43.291 1.00 26.57  ? 87  LEU A HG     1 
ATOM   1380  H HD11   . LEU A 1 87  ? -14.570 -5.692  -41.752 1.00 25.91  ? 87  LEU A HD11   1 
ATOM   1381  H HD12   . LEU A 1 87  ? -15.803 -4.996  -41.031 1.00 25.91  ? 87  LEU A HD12   1 
ATOM   1382  H HD13   . LEU A 1 87  ? -15.869 -6.539  -41.404 1.00 25.91  ? 87  LEU A HD13   1 
ATOM   1383  H HD21   . LEU A 1 87  ? -14.719 -6.477  -43.952 1.00 32.09  ? 87  LEU A HD21   1 
ATOM   1384  H HD22   . LEU A 1 87  ? -16.164 -7.138  -43.965 1.00 32.09  ? 87  LEU A HD22   1 
ATOM   1385  H HD23   . LEU A 1 87  ? -15.826 -5.947  -44.960 1.00 32.09  ? 87  LEU A HD23   1 
ATOM   1386  N N      . PHE A 1 88  ? -20.578 -4.045  -43.765 1.00 19.21  ? 88  PHE A N      1 
ATOM   1387  C CA     . PHE A 1 88  ? -22.033 -4.116  -43.604 1.00 21.39  ? 88  PHE A CA     1 
ATOM   1388  C C      . PHE A 1 88  ? -22.777 -3.563  -44.826 1.00 25.71  ? 88  PHE A C      1 
ATOM   1389  O O      . PHE A 1 88  ? -23.925 -3.928  -45.069 1.00 23.95  ? 88  PHE A O      1 
ATOM   1390  C CB     . PHE A 1 88  ? -22.498 -3.348  -42.358 1.00 20.14  ? 88  PHE A CB     1 
ATOM   1391  C CG     . PHE A 1 88  ? -22.219 -4.046  -41.051 1.00 19.20  ? 88  PHE A CG     1 
ATOM   1392  C CD1    . PHE A 1 88  ? -21.370 -5.137  -40.977 1.00 21.52  ? 88  PHE A CD1    1 
ATOM   1393  C CD2    . PHE A 1 88  ? -22.833 -3.608  -39.888 1.00 21.57  ? 88  PHE A CD2    1 
ATOM   1394  C CE1    . PHE A 1 88  ? -21.127 -5.769  -39.757 1.00 21.86  ? 88  PHE A CE1    1 
ATOM   1395  C CE2    . PHE A 1 88  ? -22.598 -4.237  -38.668 1.00 24.38  ? 88  PHE A CE2    1 
ATOM   1396  C CZ     . PHE A 1 88  ? -21.747 -5.312  -38.602 1.00 23.75  ? 88  PHE A CZ     1 
ATOM   1397  H H      . PHE A 1 88  ? -20.245 -3.273  -43.584 1.00 23.05  ? 88  PHE A H      1 
ATOM   1398  H HA     . PHE A 1 88  ? -22.302 -5.041  -43.497 1.00 25.67  ? 88  PHE A HA     1 
ATOM   1399  H HB2    . PHE A 1 88  ? -22.048 -2.489  -42.335 1.00 24.17  ? 88  PHE A HB2    1 
ATOM   1400  H HB3    . PHE A 1 88  ? -23.456 -3.212  -42.419 1.00 24.17  ? 88  PHE A HB3    1 
ATOM   1401  H HD1    . PHE A 1 88  ? -20.948 -5.447  -41.745 1.00 25.82  ? 88  PHE A HD1    1 
ATOM   1402  H HD2    . PHE A 1 88  ? -23.409 -2.879  -39.922 1.00 25.88  ? 88  PHE A HD2    1 
ATOM   1403  H HE1    . PHE A 1 88  ? -20.552 -6.499  -39.718 1.00 26.24  ? 88  PHE A HE1    1 
ATOM   1404  H HE2    . PHE A 1 88  ? -23.015 -3.926  -37.897 1.00 29.26  ? 88  PHE A HE2    1 
ATOM   1405  H HZ     . PHE A 1 88  ? -21.589 -5.734  -37.788 1.00 28.50  ? 88  PHE A HZ     1 
ATOM   1406  N N      . GLY A 1 89  ? -22.145 -2.652  -45.562 1.00 23.21  ? 89  GLY A N      1 
ATOM   1407  C CA     . GLY A 1 89  ? -22.714 -2.147  -46.799 1.00 22.91  ? 89  GLY A CA     1 
ATOM   1408  C C      . GLY A 1 89  ? -23.633 -0.945  -46.667 1.00 29.78  ? 89  GLY A C      1 
ATOM   1409  O O      . GLY A 1 89  ? -24.124 -0.439  -47.678 1.00 33.33  ? 89  GLY A O      1 
ATOM   1410  H H      . GLY A 1 89  ? -21.381 -2.311  -45.362 1.00 27.85  ? 89  GLY A H      1 
ATOM   1411  H HA2    . GLY A 1 89  ? -21.992 -1.900  -47.397 1.00 27.49  ? 89  GLY A HA2    1 
ATOM   1412  H HA3    . GLY A 1 89  ? -23.218 -2.858  -47.226 1.00 27.49  ? 89  GLY A HA3    1 
ATOM   1413  N N      . PHE A 1 90  ? -23.864 -0.468  -45.447 1.00 20.71  ? 90  PHE A N      1 
ATOM   1414  C CA     . PHE A 1 90  ? -24.754 0.674   -45.245 1.00 23.41  ? 90  PHE A CA     1 
ATOM   1415  C C      . PHE A 1 90  ? -24.081 1.964   -45.670 1.00 25.68  ? 90  PHE A C      1 
ATOM   1416  O O      . PHE A 1 90  ? -22.860 2.093   -45.619 1.00 26.03  ? 90  PHE A O      1 
ATOM   1417  C CB     . PHE A 1 90  ? -25.202 0.781   -43.782 1.00 26.16  ? 90  PHE A CB     1 
ATOM   1418  C CG     . PHE A 1 90  ? -26.044 -0.374  -43.324 1.00 26.39  ? 90  PHE A CG     1 
ATOM   1419  C CD1    . PHE A 1 90  ? -27.314 -0.569  -43.843 1.00 23.72  ? 90  PHE A CD1    1 
ATOM   1420  C CD2    . PHE A 1 90  ? -25.567 -1.264  -42.373 1.00 22.67  ? 90  PHE A CD2    1 
ATOM   1421  C CE1    . PHE A 1 90  ? -28.089 -1.637  -43.434 1.00 25.97  ? 90  PHE A CE1    1 
ATOM   1422  C CE2    . PHE A 1 90  ? -26.337 -2.336  -41.954 1.00 25.50  ? 90  PHE A CE2    1 
ATOM   1423  C CZ     . PHE A 1 90  ? -27.600 -2.524  -42.482 1.00 25.01  ? 90  PHE A CZ     1 
ATOM   1424  H H      . PHE A 1 90  ? -23.521 -0.784  -44.724 1.00 24.86  ? 90  PHE A H      1 
ATOM   1425  H HA     . PHE A 1 90  ? -25.546 0.555   -45.791 1.00 28.09  ? 90  PHE A HA     1 
ATOM   1426  H HB2    . PHE A 1 90  ? -24.415 0.818   -43.216 1.00 31.39  ? 90  PHE A HB2    1 
ATOM   1427  H HB3    . PHE A 1 90  ? -25.724 1.591   -43.673 1.00 31.39  ? 90  PHE A HB3    1 
ATOM   1428  H HD1    . PHE A 1 90  ? -27.644 0.019   -44.483 1.00 28.46  ? 90  PHE A HD1    1 
ATOM   1429  H HD2    . PHE A 1 90  ? -24.716 -1.144  -42.018 1.00 27.21  ? 90  PHE A HD2    1 
ATOM   1430  H HE1    . PHE A 1 90  ? -28.940 -1.758  -43.790 1.00 31.16  ? 90  PHE A HE1    1 
ATOM   1431  H HE2    . PHE A 1 90  ? -26.006 -2.927  -41.317 1.00 30.59  ? 90  PHE A HE2    1 
ATOM   1432  H HZ     . PHE A 1 90  ? -28.122 -3.240  -42.200 1.00 30.01  ? 90  PHE A HZ     1 
ATOM   1433  N N      . LYS A 1 91  ? -24.902 2.926   -46.075 1.00 23.92  ? 91  LYS A N      1 
ATOM   1434  C CA     . LYS A 1 91  ? -24.413 4.197   -46.589 1.00 26.77  ? 91  LYS A CA     1 
ATOM   1435  C C      . LYS A 1 91  ? -23.859 5.086   -45.482 1.00 28.31  ? 91  LYS A C      1 
ATOM   1436  O O      . LYS A 1 91  ? -22.813 5.714   -45.652 1.00 23.93  ? 91  LYS A O      1 
ATOM   1437  C CB     . LYS A 1 91  ? -25.544 4.925   -47.322 1.00 29.05  ? 91  LYS A CB     1 
ATOM   1438  C CG     . LYS A 1 91  ? -25.100 6.154   -48.081 1.00 39.15  ? 91  LYS A CG     1 
ATOM   1439  C CD     . LYS A 1 91  ? -26.227 6.701   -48.955 1.00 46.62  ? 91  LYS A CD     1 
ATOM   1440  C CE     . LYS A 1 91  ? -25.758 7.889   -49.790 1.00 50.95  ? 91  LYS A CE     1 
ATOM   1441  N NZ     . LYS A 1 91  ? -26.858 8.466   -50.610 1.00 50.00  ? 91  LYS A NZ     1 
ATOM   1442  H H      . LYS A 1 91  ? -25.760 2.865   -46.061 1.00 28.70  ? 91  LYS A H      1 
ATOM   1443  H HA     . LYS A 1 91  ? -23.700 4.029   -47.225 1.00 32.12  ? 91  LYS A HA     1 
ATOM   1444  H HB2    . LYS A 1 91  ? -25.946 4.314   -47.959 1.00 34.86  ? 91  LYS A HB2    1 
ATOM   1445  H HB3    . LYS A 1 91  ? -26.208 5.204   -46.672 1.00 34.86  ? 91  LYS A HB3    1 
ATOM   1446  H HG2    . LYS A 1 91  ? -24.837 6.843   -47.452 1.00 46.98  ? 91  LYS A HG2    1 
ATOM   1447  H HG3    . LYS A 1 91  ? -24.354 5.922   -48.657 1.00 46.98  ? 91  LYS A HG3    1 
ATOM   1448  H HD2    . LYS A 1 91  ? -26.530 6.005   -49.559 1.00 55.94  ? 91  LYS A HD2    1 
ATOM   1449  H HD3    . LYS A 1 91  ? -26.957 6.996   -48.389 1.00 55.94  ? 91  LYS A HD3    1 
ATOM   1450  H HE2    . LYS A 1 91  ? -25.426 8.583   -49.198 1.00 61.14  ? 91  LYS A HE2    1 
ATOM   1451  H HE3    . LYS A 1 91  ? -25.054 7.598   -50.391 1.00 61.14  ? 91  LYS A HE3    1 
ATOM   1452  H HZ1    . LYS A 1 91  ? -26.554 9.155   -51.084 1.00 60.00  ? 91  LYS A HZ1    1 
ATOM   1453  H HZ2    . LYS A 1 91  ? -27.177 7.850   -51.167 1.00 60.00  ? 91  LYS A HZ2    1 
ATOM   1454  H HZ3    . LYS A 1 91  ? -27.516 8.747   -50.081 1.00 60.00  ? 91  LYS A HZ3    1 
ATOM   1455  N N      . HIS A 1 92  ? -24.565 5.128   -44.352 1.00 24.94  ? 92  HIS A N      1 
ATOM   1456  C CA     . HIS A 1 92  ? -24.245 6.049   -43.262 1.00 22.86  ? 92  HIS A CA     1 
ATOM   1457  C C      . HIS A 1 92  ? -24.047 5.352   -41.922 1.00 26.62  ? 92  HIS A C      1 
ATOM   1458  O O      . HIS A 1 92  ? -24.722 4.367   -41.614 1.00 21.79  ? 92  HIS A O      1 
ATOM   1459  C CB     . HIS A 1 92  ? -25.357 7.079   -43.086 1.00 24.73  ? 92  HIS A CB     1 
ATOM   1460  C CG     . HIS A 1 92  ? -25.718 7.814   -44.335 1.00 28.25  ? 92  HIS A CG     1 
ATOM   1461  N ND1    . HIS A 1 92  ? -24.811 8.574   -45.041 1.00 29.99  ? 92  HIS A ND1    1 
ATOM   1462  C CD2    . HIS A 1 92  ? -26.899 7.934   -44.986 1.00 33.67  ? 92  HIS A CD2    1 
ATOM   1463  C CE1    . HIS A 1 92  ? -25.416 9.121   -46.081 1.00 35.64  ? 92  HIS A CE1    1 
ATOM   1464  N NE2    . HIS A 1 92  ? -26.684 8.749   -46.070 1.00 32.39  ? 92  HIS A NE2    1 
ATOM   1465  H H      . HIS A 1 92  ? -25.244 4.625   -44.191 1.00 29.93  ? 92  HIS A H      1 
ATOM   1466  H HA     . HIS A 1 92  ? -23.428 6.528   -43.468 1.00 27.43  ? 92  HIS A HA     1 
ATOM   1467  H HB2    . HIS A 1 92  ? -26.154 6.630   -42.763 1.00 29.67  ? 92  HIS A HB2    1 
ATOM   1468  H HB3    . HIS A 1 92  ? -25.059 7.731   -42.437 1.00 29.67  ? 92  HIS A HB3    1 
ATOM   1469  H HD2    . HIS A 1 92  ? -27.705 7.536   -44.746 1.00 40.40  ? 92  HIS A HD2    1 
ATOM   1470  H HE1    . HIS A 1 92  ? -25.016 9.672   -46.715 1.00 42.77  ? 92  HIS A HE1    1 
ATOM   1471  H HE2    . HIS A 1 92  ? -27.277 8.976   -46.650 1.00 38.87  ? 92  HIS A HE2    1 
ATOM   1472  N N      . ILE A 1 93  ? -23.148 5.895   -41.111 1.00 21.55  ? 93  ILE A N      1 
ATOM   1473  C CA     . ILE A 1 93  ? -22.922 5.361   -39.776 1.00 24.59  ? 93  ILE A CA     1 
ATOM   1474  C C      . ILE A 1 93  ? -22.811 6.480   -38.750 1.00 25.41  ? 93  ILE A C      1 
ATOM   1475  O O      . ILE A 1 93  ? -22.213 7.532   -39.003 1.00 23.48  ? 93  ILE A O      1 
ATOM   1476  C CB     . ILE A 1 93  ? -21.654 4.480   -39.729 1.00 24.85  ? 93  ILE A CB     1 
ATOM   1477  C CG1    . ILE A 1 93  ? -21.388 3.995   -38.297 1.00 23.69  ? 93  ILE A CG1    1 
ATOM   1478  C CG2    . ILE A 1 93  ? -20.465 5.244   -40.278 1.00 32.23  ? 93  ILE A CG2    1 
ATOM   1479  C CD1    . ILE A 1 93  ? -20.198 3.091   -38.175 1.00 30.62  ? 93  ILE A CD1    1 
ATOM   1480  H H      . ILE A 1 93  ? -22.657 6.572   -41.310 1.00 25.86  ? 93  ILE A H      1 
ATOM   1481  H HA     . ILE A 1 93  ? -23.673 4.807   -39.517 1.00 29.51  ? 93  ILE A HA     1 
ATOM   1482  H HB     . ILE A 1 93  ? -21.802 3.703   -40.291 1.00 29.82  ? 93  ILE A HB     1 
ATOM   1483  H HG12   . ILE A 1 93  ? -21.221 4.758   -37.723 1.00 28.43  ? 93  ILE A HG12   1 
ATOM   1484  H HG13   . ILE A 1 93  ? -22.165 3.508   -37.981 1.00 28.43  ? 93  ILE A HG13   1 
ATOM   1485  H HG21   . ILE A 1 93  ? -19.715 4.637   -40.345 1.00 38.67  ? 93  ILE A HG21   1 
ATOM   1486  H HG22   . ILE A 1 93  ? -20.683 5.591   -41.156 1.00 38.67  ? 93  ILE A HG22   1 
ATOM   1487  H HG23   . ILE A 1 93  ? -20.249 5.974   -39.676 1.00 38.67  ? 93  ILE A HG23   1 
ATOM   1488  H HD11   . ILE A 1 93  ? -20.197 2.687   -37.293 1.00 36.74  ? 93  ILE A HD11   1 
ATOM   1489  H HD12   . ILE A 1 93  ? -20.257 2.403   -38.855 1.00 36.74  ? 93  ILE A HD12   1 
ATOM   1490  H HD13   . ILE A 1 93  ? -19.390 3.612   -38.302 1.00 36.74  ? 93  ILE A HD13   1 
ATOM   1491  N N      . VAL A 1 94  ? -23.427 6.241   -37.599 1.00 20.08  ? 94  VAL A N      1 
ATOM   1492  C CA     . VAL A 1 94  ? -23.317 7.123   -36.442 1.00 22.11  ? 94  VAL A CA     1 
ATOM   1493  C C      . VAL A 1 94  ? -22.799 6.295   -35.259 1.00 22.34  ? 94  VAL A C      1 
ATOM   1494  O O      . VAL A 1 94  ? -23.481 5.382   -34.808 1.00 20.68  ? 94  VAL A O      1 
ATOM   1495  C CB     . VAL A 1 94  ? -24.666 7.759   -36.058 1.00 22.34  ? 94  VAL A CB     1 
ATOM   1496  C CG1    . VAL A 1 94  ? -24.487 8.715   -34.881 1.00 27.64  ? 94  VAL A CG1    1 
ATOM   1497  C CG2    . VAL A 1 94  ? -25.280 8.498   -37.251 1.00 24.41  ? 94  VAL A CG2    1 
ATOM   1498  H H      . VAL A 1 94  ? -23.928 5.556   -37.459 1.00 24.10  ? 94  VAL A H      1 
ATOM   1499  H HA     . VAL A 1 94  ? -22.699 7.840   -36.639 1.00 26.54  ? 94  VAL A HA     1 
ATOM   1500  H HB     . VAL A 1 94  ? -25.281 7.060   -35.788 1.00 26.80  ? 94  VAL A HB     1 
ATOM   1501  H HG11   . VAL A 1 94  ? -25.298 9.236   -34.774 1.00 33.17  ? 94  VAL A HG11   1 
ATOM   1502  H HG12   . VAL A 1 94  ? -24.317 8.201   -34.076 1.00 33.17  ? 94  VAL A HG12   1 
ATOM   1503  H HG13   . VAL A 1 94  ? -23.738 9.304   -35.064 1.00 33.17  ? 94  VAL A HG13   1 
ATOM   1504  H HG21   . VAL A 1 94  ? -26.147 8.848   -36.992 1.00 29.29  ? 94  VAL A HG21   1 
ATOM   1505  H HG22   . VAL A 1 94  ? -24.692 9.226   -37.507 1.00 29.29  ? 94  VAL A HG22   1 
ATOM   1506  H HG23   . VAL A 1 94  ? -25.381 7.879   -37.990 1.00 29.29  ? 94  VAL A HG23   1 
ATOM   1507  N N      . PRO A 1 95  ? -21.590 6.603   -34.762 1.00 20.87  ? 95  PRO A N      1 
ATOM   1508  C CA     . PRO A 1 95  ? -21.103 5.880   -33.582 1.00 20.23  ? 95  PRO A CA     1 
ATOM   1509  C C      . PRO A 1 95  ? -21.950 6.176   -32.349 1.00 17.77  ? 95  PRO A C      1 
ATOM   1510  O O      . PRO A 1 95  ? -22.518 7.265   -32.235 1.00 18.23  ? 95  PRO A O      1 
ATOM   1511  C CB     . PRO A 1 95  ? -19.665 6.409   -33.409 1.00 22.02  ? 95  PRO A CB     1 
ATOM   1512  C CG     . PRO A 1 95  ? -19.686 7.756   -34.040 1.00 24.15  ? 95  PRO A CG     1 
ATOM   1513  C CD     . PRO A 1 95  ? -20.648 7.653   -35.189 1.00 21.83  ? 95  PRO A CD     1 
ATOM   1514  H HA     . PRO A 1 95  ? -21.084 4.924   -33.747 1.00 24.28  ? 95  PRO A HA     1 
ATOM   1515  H HB2    . PRO A 1 95  ? -19.450 6.473   -32.465 1.00 26.42  ? 95  PRO A HB2    1 
ATOM   1516  H HB3    . PRO A 1 95  ? -19.042 5.823   -33.867 1.00 26.42  ? 95  PRO A HB3    1 
ATOM   1517  H HG2    . PRO A 1 95  ? -19.993 8.412   -33.395 1.00 28.98  ? 95  PRO A HG2    1 
ATOM   1518  H HG3    . PRO A 1 95  ? -18.797 7.980   -34.358 1.00 28.98  ? 95  PRO A HG3    1 
ATOM   1519  H HD2    . PRO A 1 95  ? -21.110 8.497   -35.309 1.00 26.20  ? 95  PRO A HD2    1 
ATOM   1520  H HD3    . PRO A 1 95  ? -20.183 7.383   -35.996 1.00 26.20  ? 95  PRO A HD3    1 
ATOM   1521  N N      . THR A 1 96  ? -22.037 5.204   -31.445 1.00 18.79  ? 96  THR A N      1 
ATOM   1522  C CA     . THR A 1 96  ? -22.708 5.380   -30.158 1.00 17.73  ? 96  THR A CA     1 
ATOM   1523  C C      . THR A 1 96  ? -21.861 4.678   -29.101 1.00 17.44  ? 96  THR A C      1 
ATOM   1524  O O      . THR A 1 96  ? -21.027 3.849   -29.452 1.00 20.37  ? 96  THR A O      1 
ATOM   1525  C CB     . THR A 1 96  ? -24.137 4.801   -30.170 1.00 22.12  ? 96  THR A CB     1 
ATOM   1526  O OG1    . THR A 1 96  ? -24.091 3.408   -30.493 1.00 22.30  ? 96  THR A OG1    1 
ATOM   1527  C CG2    . THR A 1 96  ? -25.007 5.528   -31.207 1.00 23.20  ? 96  THR A CG2    1 
ATOM   1528  H H      . THR A 1 96  ? -21.709 4.417   -31.556 1.00 22.54  ? 96  THR A H      1 
ATOM   1529  H HA     . THR A 1 96  ? -22.765 6.322   -29.939 1.00 21.27  ? 96  THR A HA     1 
ATOM   1530  H HB     . THR A 1 96  ? -24.540 4.917   -29.295 1.00 26.55  ? 96  THR A HB     1 
ATOM   1531  H HG1    . THR A 1 96  ? -23.668 2.989   -29.901 1.00 26.76  ? 96  THR A HG1    1 
ATOM   1532  H HG21   . THR A 1 96  ? -25.916 5.193   -31.169 1.00 27.84  ? 96  THR A HG21   1 
ATOM   1533  H HG22   . THR A 1 96  ? -25.014 6.480   -31.024 1.00 27.84  ? 96  THR A HG22   1 
ATOM   1534  H HG23   . THR A 1 96  ? -24.653 5.381   -32.098 1.00 27.84  ? 96  THR A HG23   1 
ATOM   1535  N N      . HIS A 1 97  ? -22.060 4.981   -27.819 1.00 18.38  ? 97  HIS A N      1 
ATOM   1536  C CA     . HIS A 1 97  ? -21.165 4.416   -26.811 1.00 20.05  ? 97  HIS A CA     1 
ATOM   1537  C C      . HIS A 1 97  ? -21.400 2.912   -26.670 1.00 21.25  ? 97  HIS A C      1 
ATOM   1538  O O      . HIS A 1 97  ? -20.464 2.176   -26.366 1.00 20.09  ? 97  HIS A O      1 
ATOM   1539  C CB     . HIS A 1 97  ? -21.302 5.141   -25.462 1.00 22.11  ? 97  HIS A CB     1 
ATOM   1540  C CG     . HIS A 1 97  ? -22.498 4.737   -24.655 1.00 22.98  ? 97  HIS A CG     1 
ATOM   1541  N ND1    . HIS A 1 97  ? -23.754 5.250   -24.873 1.00 24.44  ? 97  HIS A ND1    1 
ATOM   1542  C CD2    . HIS A 1 97  ? -22.605 3.896   -23.596 1.00 24.89  ? 97  HIS A CD2    1 
ATOM   1543  C CE1    . HIS A 1 97  ? -24.601 4.722   -23.998 1.00 25.68  ? 97  HIS A CE1    1 
ATOM   1544  N NE2    . HIS A 1 97  ? -23.926 3.900   -23.217 1.00 26.12  ? 97  HIS A NE2    1 
ATOM   1545  H H      . HIS A 1 97  ? -22.682 5.492   -27.515 1.00 22.06  ? 97  HIS A H      1 
ATOM   1546  H HA     . HIS A 1 97  ? -20.253 4.543   -27.111 1.00 24.06  ? 97  HIS A HA     1 
ATOM   1547  H HB2    . HIS A 1 97  ? -20.512 4.957   -24.930 1.00 26.53  ? 97  HIS A HB2    1 
ATOM   1548  H HB3    . HIS A 1 97  ? -21.368 6.094   -25.628 1.00 26.53  ? 97  HIS A HB3    1 
ATOM   1549  H HD1    . HIS A 1 97  ? -23.961 5.813   -25.488 1.00 29.33  ? 97  HIS A HD1    1 
ATOM   1550  H HD2    . HIS A 1 97  ? -21.919 3.399   -23.211 1.00 29.86  ? 97  HIS A HD2    1 
ATOM   1551  H HE1    . HIS A 1 97  ? -25.512 4.902   -23.944 1.00 30.82  ? 97  HIS A HE1    1 
ATOM   1552  H HE2    . HIS A 1 97  ? -24.258 3.441   -22.571 1.00 31.35  ? 97  HIS A HE2    1 
ATOM   1553  N N      . GLN A 1 98  ? -22.629 2.459   -26.914 1.00 19.42  ? 98  GLN A N      1 
ATOM   1554  C CA     . GLN A 1 98  ? -22.900 1.029   -27.106 1.00 19.83  ? 98  GLN A CA     1 
ATOM   1555  C C      . GLN A 1 98  ? -24.283 0.856   -27.747 1.00 22.86  ? 98  GLN A C      1 
ATOM   1556  O O      . GLN A 1 98  ? -24.884 1.832   -28.218 1.00 20.84  ? 98  GLN A O      1 
ATOM   1557  C CB     . GLN A 1 98  ? -22.782 0.248   -25.788 1.00 20.80  ? 98  GLN A CB     1 
ATOM   1558  C CG     . GLN A 1 98  ? -23.753 0.629   -24.691 1.00 20.49  ? 98  GLN A CG     1 
ATOM   1559  C CD     . GLN A 1 98  ? -23.446 -0.089  -23.371 1.00 27.25  ? 98  GLN A CD     1 
ATOM   1560  O OE1    . GLN A 1 98  ? -22.367 0.079   -22.791 1.00 21.60  ? 98  GLN A OE1    1 
ATOM   1561  N NE2    . GLN A 1 98  ? -24.388 -0.910  -22.907 1.00 21.84  ? 98  GLN A NE2    1 
ATOM   1562  H H      . GLN A 1 98  ? -23.327 2.958   -26.974 1.00 23.30  ? 98  GLN A H      1 
ATOM   1563  H HA     . GLN A 1 98  ? -22.244 0.668   -27.721 1.00 23.80  ? 98  GLN A HA     1 
ATOM   1564  H HB2    . GLN A 1 98  ? -22.908 -0.692  -25.976 1.00 24.96  ? 98  GLN A HB2    1 
ATOM   1565  H HB3    . GLN A 1 98  ? -21.890 0.381   -25.434 1.00 24.96  ? 98  GLN A HB3    1 
ATOM   1566  H HG2    . GLN A 1 98  ? -23.700 1.584   -24.536 1.00 24.59  ? 98  GLN A HG2    1 
ATOM   1567  H HG3    . GLN A 1 98  ? -24.651 0.386   -24.964 1.00 24.59  ? 98  GLN A HG3    1 
ATOM   1568  H HE21   . GLN A 1 98  ? -25.119 -1.019  -23.347 1.00 26.20  ? 98  GLN A HE21   1 
ATOM   1569  H HE22   . GLN A 1 98  ? -24.265 -1.331  -22.167 1.00 26.20  ? 98  GLN A HE22   1 
ATOM   1570  N N      . GLY A 1 99  ? -24.768 -0.380  -27.785 1.00 17.79  ? 99  GLY A N      1 
ATOM   1571  C CA     . GLY A 1 99  ? -25.963 -0.726  -28.537 1.00 19.53  ? 99  GLY A CA     1 
ATOM   1572  C C      . GLY A 1 99  ? -27.199 0.066   -28.164 1.00 19.68  ? 99  GLY A C      1 
ATOM   1573  O O      . GLY A 1 99  ? -27.914 0.570   -29.035 1.00 21.23  ? 99  GLY A O      1 
ATOM   1574  H H      . GLY A 1 99  ? -24.415 -1.048  -27.376 1.00 21.34  ? 99  GLY A H      1 
ATOM   1575  H HA2    . GLY A 1 99  ? -25.792 -0.587  -29.482 1.00 23.44  ? 99  GLY A HA2    1 
ATOM   1576  H HA3    . GLY A 1 99  ? -26.158 -1.667  -28.403 1.00 23.44  ? 99  GLY A HA3    1 
ATOM   1577  N N      . ARG A 1 100 ? -27.468 0.186   -26.870 1.00 21.93  ? 100 ARG A N      1 
ATOM   1578  C CA     . ARG A 1 100 ? -28.714 0.813   -26.447 1.00 22.22  ? 100 ARG A CA     1 
ATOM   1579  C C      . ARG A 1 100 ? -28.706 2.313   -26.750 1.00 22.93  ? 100 ARG A C      1 
ATOM   1580  O O      . ARG A 1 100 ? -29.764 2.930   -26.858 1.00 22.76  ? 100 ARG A O      1 
ATOM   1581  C CB     . ARG A 1 100 ? -28.990 0.540   -24.963 1.00 21.81  ? 100 ARG A CB     1 
ATOM   1582  C CG     . ARG A 1 100 ? -27.912 0.956   -23.987 1.00 24.12  ? 100 ARG A CG     1 
ATOM   1583  C CD     . ARG A 1 100 ? -28.032 0.147   -22.686 1.00 23.27  ? 100 ARG A CD     1 
ATOM   1584  N NE     . ARG A 1 100 ? -27.576 -1.232  -22.862 1.00 23.07  ? 100 ARG A NE     1 
ATOM   1585  C CZ     . ARG A 1 100 ? -27.555 -2.159  -21.904 1.00 26.64  ? 100 ARG A CZ     1 
ATOM   1586  N NH1    . ARG A 1 100 ? -27.992 -1.879  -20.678 1.00 23.15  ? 100 ARG A NH1    1 
ATOM   1587  N NH2    . ARG A 1 100 ? -27.103 -3.383  -22.173 1.00 26.29  ? 100 ARG A NH2    1 
ATOM   1588  H H      . ARG A 1 100 ? -26.959 -0.083  -26.231 1.00 26.31  ? 100 ARG A H      1 
ATOM   1589  H HA     . ARG A 1 100 ? -29.441 0.421   -26.954 1.00 26.67  ? 100 ARG A HA     1 
ATOM   1590  H HB2    . ARG A 1 100 ? -29.800 1.012   -24.714 1.00 26.17  ? 100 ARG A HB2    1 
ATOM   1591  H HB3    . ARG A 1 100 ? -29.127 -0.414  -24.851 1.00 26.17  ? 100 ARG A HB3    1 
ATOM   1592  H HG2    . ARG A 1 100 ? -27.038 0.790   -24.372 1.00 28.94  ? 100 ARG A HG2    1 
ATOM   1593  H HG3    . ARG A 1 100 ? -28.015 1.897   -23.774 1.00 28.94  ? 100 ARG A HG3    1 
ATOM   1594  H HD2    . ARG A 1 100 ? -27.486 0.562   -22.000 1.00 27.92  ? 100 ARG A HD2    1 
ATOM   1595  H HD3    . ARG A 1 100 ? -28.961 0.126   -22.407 1.00 27.92  ? 100 ARG A HD3    1 
ATOM   1596  H HE     . ARG A 1 100 ? -27.338 -1.473  -23.652 1.00 27.69  ? 100 ARG A HE     1 
ATOM   1597  H HH11   . ARG A 1 100 ? -28.283 -1.091  -20.492 1.00 27.78  ? 100 ARG A HH11   1 
ATOM   1598  H HH12   . ARG A 1 100 ? -27.977 -2.486  -20.069 1.00 27.78  ? 100 ARG A HH12   1 
ATOM   1599  H HH21   . ARG A 1 100 ? -26.824 -3.574  -22.964 1.00 31.55  ? 100 ARG A HH21   1 
ATOM   1600  H HH22   . ARG A 1 100 ? -27.098 -3.984  -21.558 1.00 31.55  ? 100 ARG A HH22   1 
ATOM   1601  N N      . GLY A 1 101 ? -27.526 2.895   -26.928 1.00 22.33  ? 101 GLY A N      1 
ATOM   1602  C CA     . GLY A 1 101 ? -27.441 4.251   -27.434 1.00 22.37  ? 101 GLY A CA     1 
ATOM   1603  C C      . GLY A 1 101 ? -27.990 4.346   -28.850 1.00 24.17  ? 101 GLY A C      1 
ATOM   1604  O O      . GLY A 1 101 ? -28.737 5.274   -29.179 1.00 22.97  ? 101 GLY A O      1 
ATOM   1605  H H      . GLY A 1 101 ? -26.766 2.527   -26.763 1.00 26.80  ? 101 GLY A H      1 
ATOM   1606  H HA2    . GLY A 1 101 ? -27.950 4.847   -26.862 1.00 26.84  ? 101 GLY A HA2    1 
ATOM   1607  H HA3    . GLY A 1 101 ? -26.515 4.541   -27.439 1.00 26.84  ? 101 GLY A HA3    1 
ATOM   1608  N N      . ALA A 1 102 ? -27.618 3.385   -29.696 1.00 20.94  ? 102 ALA A N      1 
ATOM   1609  C CA     . ALA A 1 102 ? -28.106 3.344   -31.070 1.00 21.60  ? 102 ALA A CA     1 
ATOM   1610  C C      . ALA A 1 102 ? -29.617 3.093   -31.104 1.00 25.86  ? 102 ALA A C      1 
ATOM   1611  O O      . ALA A 1 102 ? -30.334 3.636   -31.953 1.00 23.85  ? 102 ALA A O      1 
ATOM   1612  C CB     . ALA A 1 102 ? -27.373 2.278   -31.857 1.00 21.65  ? 102 ALA A CB     1 
ATOM   1613  H H      . ALA A 1 102 ? -27.081 2.743   -29.496 1.00 25.13  ? 102 ALA A H      1 
ATOM   1614  H HA     . ALA A 1 102 ? -27.936 4.200   -31.493 1.00 25.92  ? 102 ALA A HA     1 
ATOM   1615  H HB1    . ALA A 1 102 ? -27.704 2.276   -32.769 1.00 25.98  ? 102 ALA A HB1    1 
ATOM   1616  H HB2    . ALA A 1 102 ? -26.424 2.478   -31.850 1.00 25.98  ? 102 ALA A HB2    1 
ATOM   1617  H HB3    . ALA A 1 102 ? -27.533 1.415   -31.445 1.00 25.98  ? 102 ALA A HB3    1 
ATOM   1618  N N      . GLU A 1 103 ? -30.092 2.271   -30.176 1.00 23.62  ? 103 GLU A N      1 
ATOM   1619  C CA     . GLU A 1 103 ? -31.518 1.961   -30.083 1.00 28.62  ? 103 GLU A CA     1 
ATOM   1620  C C      . GLU A 1 103 ? -32.332 3.199   -29.728 1.00 27.13  ? 103 GLU A C      1 
ATOM   1621  O O      . GLU A 1 103 ? -33.395 3.443   -30.305 1.00 25.82  ? 103 GLU A O      1 
ATOM   1622  C CB     . GLU A 1 103 ? -31.747 0.863   -29.052 1.00 27.36  ? 103 GLU A CB     1 
ATOM   1623  C CG     . GLU A 1 103 ? -31.139 -0.452  -29.475 1.00 27.74  ? 103 GLU A CG     1 
ATOM   1624  C CD     . GLU A 1 103 ? -31.161 -1.500  -28.383 1.00 40.19  ? 103 GLU A CD     1 
ATOM   1625  O OE1    . GLU A 1 103 ? -31.345 -1.163  -27.189 1.00 31.14  ? 103 GLU A OE1    1 
ATOM   1626  O OE2    . GLU A 1 103 ? -30.999 -2.678  -28.737 1.00 44.89  ? 103 GLU A OE2    1 
ATOM   1627  H H      . GLU A 1 103 ? -29.609 1.876   -29.584 1.00 28.34  ? 103 GLU A H      1 
ATOM   1628  H HA     . GLU A 1 103 ? -31.827 1.635   -30.943 1.00 34.35  ? 103 GLU A HA     1 
ATOM   1629  H HB2    . GLU A 1 103 ? -31.340 1.130   -28.213 1.00 32.83  ? 103 GLU A HB2    1 
ATOM   1630  H HB3    . GLU A 1 103 ? -32.700 0.731   -28.933 1.00 32.83  ? 103 GLU A HB3    1 
ATOM   1631  H HG2    . GLU A 1 103 ? -31.638 -0.799  -30.231 1.00 33.29  ? 103 GLU A HG2    1 
ATOM   1632  H HG3    . GLU A 1 103 ? -30.215 -0.306  -29.730 1.00 33.29  ? 103 GLU A HG3    1 
ATOM   1633  N N      . ASN A 1 104 ? -31.824 3.973   -28.777 1.00 26.79  ? 104 ASN A N      1 
ATOM   1634  C CA     . ASN A 1 104 ? -32.435 5.249   -28.406 1.00 28.92  ? 104 ASN A CA     1 
ATOM   1635  C C      . ASN A 1 104 ? -32.620 6.135   -29.637 1.00 30.70  ? 104 ASN A C      1 
ATOM   1636  O O      . ASN A 1 104 ? -33.704 6.675   -29.877 1.00 25.72  ? 104 ASN A O      1 
ATOM   1637  C CB     . ASN A 1 104 ? -31.576 5.961   -27.356 1.00 29.03  ? 104 ASN A CB     1 
ATOM   1638  C CG     . ASN A 1 104 ? -32.130 7.322   -26.964 1.00 34.84  ? 104 ASN A CG     1 
ATOM   1639  O OD1    . ASN A 1 104 ? -33.335 7.483   -26.772 1.00 30.39  ? 104 ASN A OD1    1 
ATOM   1640  N ND2    . ASN A 1 104 ? -31.247 8.311   -26.842 1.00 33.48  ? 104 ASN A ND2    1 
ATOM   1641  H H      . ASN A 1 104 ? -31.118 3.782   -28.325 1.00 32.15  ? 104 ASN A H      1 
ATOM   1642  H HA     . ASN A 1 104 ? -33.309 5.083   -28.019 1.00 34.70  ? 104 ASN A HA     1 
ATOM   1643  H HB2    . ASN A 1 104 ? -31.535 5.413   -26.557 1.00 34.83  ? 104 ASN A HB2    1 
ATOM   1644  H HB3    . ASN A 1 104 ? -30.684 6.093   -27.714 1.00 34.83  ? 104 ASN A HB3    1 
ATOM   1645  H HD21   . ASN A 1 104 ? -31.512 9.099   -26.623 1.00 40.18  ? 104 ASN A HD21   1 
ATOM   1646  H HD22   . ASN A 1 104 ? -30.412 8.162   -26.982 1.00 40.18  ? 104 ASN A HD22   1 
ATOM   1647  N N      . LEU A 1 105 ? -31.566 6.269   -30.433 1.00 26.72  ? 105 LEU A N      1 
ATOM   1648  C CA     . LEU A 1 105 ? -31.634 7.092   -31.636 1.00 27.07  ? 105 LEU A CA     1 
ATOM   1649  C C      . LEU A 1 105 ? -32.650 6.558   -32.638 1.00 30.50  ? 105 LEU A C      1 
ATOM   1650  O O      . LEU A 1 105 ? -33.509 7.298   -33.115 1.00 28.64  ? 105 LEU A O      1 
ATOM   1651  C CB     . LEU A 1 105 ? -30.265 7.173   -32.306 1.00 28.30  ? 105 LEU A CB     1 
ATOM   1652  C CG     . LEU A 1 105 ? -29.113 7.766   -31.496 1.00 28.48  ? 105 LEU A CG     1 
ATOM   1653  C CD1    . LEU A 1 105 ? -27.870 7.827   -32.370 1.00 28.91  ? 105 LEU A CD1    1 
ATOM   1654  C CD2    . LEU A 1 105 ? -29.485 9.147   -30.972 1.00 29.10  ? 105 LEU A CD2    1 
ATOM   1655  H H      . LEU A 1 105 ? -30.802 5.896   -30.301 1.00 32.06  ? 105 LEU A H      1 
ATOM   1656  H HA     . LEU A 1 105 ? -31.905 7.990   -31.389 1.00 32.48  ? 105 LEU A HA     1 
ATOM   1657  H HB2    . LEU A 1 105 ? -30.001 6.274   -32.557 1.00 33.96  ? 105 LEU A HB2    1 
ATOM   1658  H HB3    . LEU A 1 105 ? -30.355 7.713   -33.107 1.00 33.96  ? 105 LEU A HB3    1 
ATOM   1659  H HG     . LEU A 1 105 ? -28.924 7.194   -30.737 1.00 34.17  ? 105 LEU A HG     1 
ATOM   1660  H HD11   . LEU A 1 105 ? -27.140 8.203   -31.854 1.00 34.70  ? 105 LEU A HD11   1 
ATOM   1661  H HD12   . LEU A 1 105 ? -27.644 6.929   -32.659 1.00 34.70  ? 105 LEU A HD12   1 
ATOM   1662  H HD13   . LEU A 1 105 ? -28.053 8.387   -33.140 1.00 34.70  ? 105 LEU A HD13   1 
ATOM   1663  H HD21   . LEU A 1 105 ? -28.703 9.549   -30.562 1.00 34.92  ? 105 LEU A HD21   1 
ATOM   1664  H HD22   . LEU A 1 105 ? -29.788 9.694   -31.713 1.00 34.92  ? 105 LEU A HD22   1 
ATOM   1665  H HD23   . LEU A 1 105 ? -30.193 9.057   -30.316 1.00 34.92  ? 105 LEU A HD23   1 
ATOM   1666  N N      . LEU A 1 106 ? -32.543 5.278   -32.974 1.00 26.02  ? 106 LEU A N      1 
ATOM   1667  C CA     . LEU A 1 106 ? -33.417 4.688   -33.982 1.00 27.05  ? 106 LEU A CA     1 
ATOM   1668  C C      . LEU A 1 106 ? -34.893 4.820   -33.612 1.00 25.22  ? 106 LEU A C      1 
ATOM   1669  O O      . LEU A 1 106 ? -35.715 5.222   -34.439 1.00 28.02  ? 106 LEU A O      1 
ATOM   1670  C CB     . LEU A 1 106 ? -33.079 3.213   -34.190 1.00 27.57  ? 106 LEU A CB     1 
ATOM   1671  C CG     . LEU A 1 106 ? -34.021 2.456   -35.130 1.00 29.77  ? 106 LEU A CG     1 
ATOM   1672  C CD1    . LEU A 1 106 ? -34.025 3.080   -36.517 1.00 27.79  ? 106 LEU A CD1    1 
ATOM   1673  C CD2    . LEU A 1 106 ? -33.639 0.986   -35.212 1.00 30.89  ? 106 LEU A CD2    1 
ATOM   1674  H H      . LEU A 1 106 ? -31.974 4.730   -32.634 1.00 31.23  ? 106 LEU A H      1 
ATOM   1675  H HA     . LEU A 1 106 ? -33.278 5.149   -34.824 1.00 32.46  ? 106 LEU A HA     1 
ATOM   1676  H HB2    . LEU A 1 106 ? -32.185 3.151   -34.561 1.00 33.08  ? 106 LEU A HB2    1 
ATOM   1677  H HB3    . LEU A 1 106 ? -33.105 2.767   -33.329 1.00 33.08  ? 106 LEU A HB3    1 
ATOM   1678  H HG     . LEU A 1 106 ? -34.925 2.499   -34.782 1.00 35.73  ? 106 LEU A HG     1 
ATOM   1679  H HD11   . LEU A 1 106 ? -34.550 2.521   -37.112 1.00 33.35  ? 106 LEU A HD11   1 
ATOM   1680  H HD12   . LEU A 1 106 ? -34.417 3.966   -36.465 1.00 33.35  ? 106 LEU A HD12   1 
ATOM   1681  H HD13   . LEU A 1 106 ? -33.112 3.139   -36.839 1.00 33.35  ? 106 LEU A HD13   1 
ATOM   1682  H HD21   . LEU A 1 106 ? -34.253 0.534   -35.812 1.00 37.07  ? 106 LEU A HD21   1 
ATOM   1683  H HD22   . LEU A 1 106 ? -32.733 0.914   -35.550 1.00 37.07  ? 106 LEU A HD22   1 
ATOM   1684  H HD23   . LEU A 1 106 ? -33.694 0.596   -34.326 1.00 37.07  ? 106 LEU A HD23   1 
ATOM   1685  N N      . SER A 1 107 ? -35.229 4.472   -32.377 1.00 26.71  ? 107 SER A N      1 
ATOM   1686  C CA     . SER A 1 107 ? -36.625 4.465   -31.958 1.00 30.96  ? 107 SER A CA     1 
ATOM   1687  C C      . SER A 1 107 ? -37.173 5.881   -31.849 1.00 35.34  ? 107 SER A C      1 
ATOM   1688  O O      . SER A 1 107 ? -38.360 6.106   -32.063 1.00 33.19  ? 107 SER A O      1 
ATOM   1689  C CB     . SER A 1 107 ? -36.786 3.734   -30.628 1.00 31.94  ? 107 SER A CB     1 
ATOM   1690  O OG     . SER A 1 107 ? -36.589 2.341   -30.806 1.00 31.23  ? 107 SER A OG     1 
ATOM   1691  H H      . SER A 1 107 ? -34.672 4.237   -31.765 1.00 32.05  ? 107 SER A H      1 
ATOM   1692  H HA     . SER A 1 107 ? -37.150 3.992   -32.623 1.00 37.15  ? 107 SER A HA     1 
ATOM   1693  H HB2    . SER A 1 107 ? -36.128 4.070   -29.999 1.00 38.33  ? 107 SER A HB2    1 
ATOM   1694  H HB3    . SER A 1 107 ? -37.681 3.887   -30.288 1.00 38.33  ? 107 SER A HB3    1 
ATOM   1695  H HG     . SER A 1 107 ? -37.152 2.039   -31.351 1.00 37.47  ? 107 SER A HG     1 
ATOM   1696  N N      . SER A 1 108 ? -36.303 6.832   -31.528 1.00 31.05  ? 108 SER A N      1 
ATOM   1697  C CA     . SER A 1 108 ? -36.696 8.233   -31.475 1.00 31.39  ? 108 SER A CA     1 
ATOM   1698  C C      . SER A 1 108 ? -36.984 8.788   -32.864 1.00 32.63  ? 108 SER A C      1 
ATOM   1699  O O      . SER A 1 108 ? -37.802 9.694   -33.017 1.00 35.38  ? 108 SER A O      1 
ATOM   1700  C CB     . SER A 1 108 ? -35.608 9.063   -30.796 1.00 33.33  ? 108 SER A CB     1 
ATOM   1701  O OG     . SER A 1 108 ? -35.408 8.624   -29.461 1.00 45.44  ? 108 SER A OG     1 
ATOM   1702  H H      . SER A 1 108 ? -35.477 6.691   -31.336 1.00 37.26  ? 108 SER A H      1 
ATOM   1703  H HA     . SER A 1 108 ? -37.505 8.315   -30.950 1.00 37.67  ? 108 SER A HA     1 
ATOM   1704  H HB2    . SER A 1 108 ? -34.779 8.963   -31.290 1.00 40.00  ? 108 SER A HB2    1 
ATOM   1705  H HB3    . SER A 1 108 ? -35.880 9.994   -30.786 1.00 40.00  ? 108 SER A HB3    1 
ATOM   1706  H HG     . SER A 1 108 ? -35.176 7.817   -29.456 1.00 54.52  ? 108 SER A HG     1 
ATOM   1707  N N      . LEU A 1 109 ? -36.315 8.240   -33.874 1.00 32.47  ? 109 LEU A N      1 
ATOM   1708  C CA     . LEU A 1 109 ? -36.427 8.755   -35.237 1.00 29.61  ? 109 LEU A CA     1 
ATOM   1709  C C      . LEU A 1 109 ? -37.489 8.052   -36.074 1.00 35.23  ? 109 LEU A C      1 
ATOM   1710  O O      . LEU A 1 109 ? -38.071 8.655   -36.970 1.00 34.38  ? 109 LEU A O      1 
ATOM   1711  C CB     . LEU A 1 109 ? -35.086 8.630   -35.962 1.00 29.36  ? 109 LEU A CB     1 
ATOM   1712  C CG     . LEU A 1 109 ? -33.922 9.429   -35.386 1.00 31.39  ? 109 LEU A CG     1 
ATOM   1713  C CD1    . LEU A 1 109 ? -32.613 8.953   -35.992 1.00 32.93  ? 109 LEU A CD1    1 
ATOM   1714  C CD2    . LEU A 1 109 ? -34.127 10.904  -35.641 1.00 34.85  ? 109 LEU A CD2    1 
ATOM   1715  H H      . LEU A 1 109 ? -35.786 7.566   -33.797 1.00 38.96  ? 109 LEU A H      1 
ATOM   1716  H HA     . LEU A 1 109 ? -36.655 9.697   -35.203 1.00 35.53  ? 109 LEU A HA     1 
ATOM   1717  H HB2    . LEU A 1 109 ? -34.825 7.696   -35.956 1.00 35.24  ? 109 LEU A HB2    1 
ATOM   1718  H HB3    . LEU A 1 109 ? -35.209 8.922   -36.879 1.00 35.24  ? 109 LEU A HB3    1 
ATOM   1719  H HG     . LEU A 1 109 ? -33.883 9.298   -34.427 1.00 37.67  ? 109 LEU A HG     1 
ATOM   1720  H HD11   . LEU A 1 109 ? -31.879 9.410   -35.554 1.00 39.52  ? 109 LEU A HD11   1 
ATOM   1721  H HD12   . LEU A 1 109 ? -32.533 7.996   -35.858 1.00 39.52  ? 109 LEU A HD12   1 
ATOM   1722  H HD13   . LEU A 1 109 ? -32.612 9.155   -36.941 1.00 39.52  ? 109 LEU A HD13   1 
ATOM   1723  H HD21   . LEU A 1 109 ? -33.354 11.391  -35.315 1.00 41.81  ? 109 LEU A HD21   1 
ATOM   1724  H HD22   . LEU A 1 109 ? -34.230 11.048  -36.595 1.00 41.81  ? 109 LEU A HD22   1 
ATOM   1725  H HD23   . LEU A 1 109 ? -34.924 11.198  -35.173 1.00 41.81  ? 109 LEU A HD23   1 
ATOM   1726  N N      . ALA A 1 110 ? -37.730 6.778   -35.793 1.00 29.10  ? 110 ALA A N      1 
ATOM   1727  C CA     . ALA A 1 110 ? -38.482 5.932   -36.719 1.00 33.78  ? 110 ALA A CA     1 
ATOM   1728  C C      . ALA A 1 110 ? -39.874 5.531   -36.212 1.00 32.54  ? 110 ALA A C      1 
ATOM   1729  O O      . ALA A 1 110 ? -40.578 4.785   -36.890 1.00 34.71  ? 110 ALA A O      1 
ATOM   1730  C CB     . ALA A 1 110 ? -37.666 4.684   -37.034 1.00 31.69  ? 110 ALA A CB     1 
ATOM   1731  H H      . ALA A 1 110 ? -37.472 6.378   -35.077 1.00 34.92  ? 110 ALA A H      1 
ATOM   1732  H HA     . ALA A 1 110 ? -38.607 6.406   -37.555 1.00 40.53  ? 110 ALA A HA     1 
ATOM   1733  H HB1    . ALA A 1 110 ? -38.164 4.129   -37.655 1.00 38.03  ? 110 ALA A HB1    1 
ATOM   1734  H HB2    . ALA A 1 110 ? -36.823 4.951   -37.432 1.00 38.03  ? 110 ALA A HB2    1 
ATOM   1735  H HB3    . ALA A 1 110 ? -37.504 4.197   -36.211 1.00 38.03  ? 110 ALA A HB3    1 
ATOM   1736  N N      . ILE A 1 111 ? -40.268 6.027   -35.040 1.00 34.51  ? 111 ILE A N      1 
ATOM   1737  C CA     . ILE A 1 111 ? -41.542 5.640   -34.427 1.00 34.80  ? 111 ILE A CA     1 
ATOM   1738  C C      . ILE A 1 111 ? -42.444 6.836   -34.126 1.00 40.04  ? 111 ILE A C      1 
ATOM   1739  O O      . ILE A 1 111 ? -42.056 7.756   -33.401 1.00 37.99  ? 111 ILE A O      1 
ATOM   1740  C CB     . ILE A 1 111 ? -41.320 4.864   -33.122 1.00 31.11  ? 111 ILE A CB     1 
ATOM   1741  C CG1    . ILE A 1 111 ? -40.516 3.592   -33.402 1.00 33.66  ? 111 ILE A CG1    1 
ATOM   1742  C CG2    . ILE A 1 111 ? -42.663 4.510   -32.461 1.00 38.19  ? 111 ILE A CG2    1 
ATOM   1743  C CD1    . ILE A 1 111 ? -40.175 2.784   -32.164 1.00 28.74  ? 111 ILE A CD1    1 
ATOM   1744  H H      . ILE A 1 111 ? -39.816 6.592   -34.576 1.00 41.41  ? 111 ILE A H      1 
ATOM   1745  H HA     . ILE A 1 111 ? -42.029 5.058   -35.029 1.00 41.76  ? 111 ILE A HA     1 
ATOM   1746  H HB     . ILE A 1 111 ? -40.814 5.423   -32.512 1.00 37.33  ? 111 ILE A HB     1 
ATOM   1747  H HG12   . ILE A 1 111 ? -41.032 3.022   -33.993 1.00 40.40  ? 111 ILE A HG12   1 
ATOM   1748  H HG13   . ILE A 1 111 ? -39.681 3.837   -33.830 1.00 40.40  ? 111 ILE A HG13   1 
ATOM   1749  H HG21   . ILE A 1 111 ? -42.495 3.962   -31.680 1.00 45.83  ? 111 ILE A HG21   1 
ATOM   1750  H HG22   . ILE A 1 111 ? -43.117 5.321   -32.186 1.00 45.83  ? 111 ILE A HG22   1 
ATOM   1751  H HG23   . ILE A 1 111 ? -43.209 4.022   -33.097 1.00 45.83  ? 111 ILE A HG23   1 
ATOM   1752  H HD11   . ILE A 1 111 ? -39.489 2.136   -32.390 1.00 34.49  ? 111 ILE A HD11   1 
ATOM   1753  H HD12   . ILE A 1 111 ? -39.849 3.385   -31.476 1.00 34.49  ? 111 ILE A HD12   1 
ATOM   1754  H HD13   . ILE A 1 111 ? -40.972 2.327   -31.854 1.00 34.49  ? 111 ILE A HD13   1 
ATOM   1755  N N      . LYS A 1 112 ? -43.651 6.797   -34.688 1.00 42.33  ? 112 LYS A N      1 
ATOM   1756  C CA     . LYS A 1 112 ? -44.725 7.720   -34.327 1.00 42.64  ? 112 LYS A CA     1 
ATOM   1757  C C      . LYS A 1 112 ? -45.581 7.062   -33.242 1.00 44.32  ? 112 LYS A C      1 
ATOM   1758  O O      . LYS A 1 112 ? -45.814 5.851   -33.289 1.00 41.48  ? 112 LYS A O      1 
ATOM   1759  C CB     . LYS A 1 112 ? -45.589 8.069   -35.546 1.00 46.89  ? 112 LYS A CB     1 
ATOM   1760  C CG     . LYS A 1 112 ? -44.826 8.658   -36.731 1.00 53.62  ? 112 LYS A CG     1 
ATOM   1761  C CD     . LYS A 1 112 ? -45.676 8.647   -38.001 1.00 63.48  ? 112 LYS A CD     1 
ATOM   1762  C CE     . LYS A 1 112 ? -44.883 9.107   -39.220 1.00 69.57  ? 112 LYS A CE     1 
ATOM   1763  N NZ     . LYS A 1 112 ? -45.594 8.827   -40.502 1.00 81.68  ? 112 LYS A NZ     1 
ATOM   1764  H H      . LYS A 1 112 ? -43.877 6.231   -35.295 1.00 50.80  ? 112 LYS A H      1 
ATOM   1765  H HA     . LYS A 1 112 ? -44.338 8.540   -33.987 1.00 51.17  ? 112 LYS A HA     1 
ATOM   1766  H HB2    . LYS A 1 112 ? -46.029 7.261   -35.854 1.00 56.27  ? 112 LYS A HB2    1 
ATOM   1767  H HB3    . LYS A 1 112 ? -46.256 8.719   -35.275 1.00 56.27  ? 112 LYS A HB3    1 
ATOM   1768  H HG2    . LYS A 1 112 ? -44.586 9.577   -36.533 1.00 64.34  ? 112 LYS A HG2    1 
ATOM   1769  H HG3    . LYS A 1 112 ? -44.029 8.131   -36.895 1.00 64.34  ? 112 LYS A HG3    1 
ATOM   1770  H HD2    . LYS A 1 112 ? -45.990 7.744   -38.167 1.00 76.18  ? 112 LYS A HD2    1 
ATOM   1771  H HD3    . LYS A 1 112 ? -46.429 9.247   -37.886 1.00 76.18  ? 112 LYS A HD3    1 
ATOM   1772  H HE2    . LYS A 1 112 ? -44.736 10.064  -39.160 1.00 83.48  ? 112 LYS A HE2    1 
ATOM   1773  H HE3    . LYS A 1 112 ? -44.033 8.641   -39.239 1.00 83.48  ? 112 LYS A HE3    1 
ATOM   1774  H HZ1    . LYS A 1 112 ? -45.103 9.108   -41.189 1.00 98.02  ? 112 LYS A HZ1    1 
ATOM   1775  H HZ2    . LYS A 1 112 ? -45.736 7.952   -40.586 1.00 98.02  ? 112 LYS A HZ2    1 
ATOM   1776  H HZ3    . LYS A 1 112 ? -46.377 9.250   -40.514 1.00 98.02  ? 112 LYS A HZ3    1 
ATOM   1777  N N      . PRO A 1 113 ? -46.049 7.843   -32.255 1.00 44.82  ? 113 PRO A N      1 
ATOM   1778  C CA     . PRO A 1 113 ? -46.907 7.249   -31.218 1.00 41.41  ? 113 PRO A CA     1 
ATOM   1779  C C      . PRO A 1 113 ? -48.137 6.539   -31.794 1.00 46.01  ? 113 PRO A C      1 
ATOM   1780  O O      . PRO A 1 113 ? -48.782 7.063   -32.701 1.00 40.87  ? 113 PRO A O      1 
ATOM   1781  C CB     . PRO A 1 113 ? -47.317 8.455   -30.371 1.00 44.86  ? 113 PRO A CB     1 
ATOM   1782  C CG     . PRO A 1 113 ? -46.209 9.440   -30.561 1.00 47.94  ? 113 PRO A CG     1 
ATOM   1783  C CD     . PRO A 1 113 ? -45.732 9.255   -31.970 1.00 49.52  ? 113 PRO A CD     1 
ATOM   1784  H HA     . PRO A 1 113 ? -46.400 6.628   -30.673 1.00 49.70  ? 113 PRO A HA     1 
ATOM   1785  H HB2    . PRO A 1 113 ? -48.157 8.814   -30.696 1.00 53.83  ? 113 PRO A HB2    1 
ATOM   1786  H HB3    . PRO A 1 113 ? -47.390 8.193   -29.440 1.00 53.83  ? 113 PRO A HB3    1 
ATOM   1787  H HG2    . PRO A 1 113 ? -46.548 10.339  -30.432 1.00 57.53  ? 113 PRO A HG2    1 
ATOM   1788  H HG3    . PRO A 1 113 ? -45.495 9.251   -29.932 1.00 57.53  ? 113 PRO A HG3    1 
ATOM   1789  H HD2    . PRO A 1 113 ? -46.218 9.840   -32.572 1.00 59.43  ? 113 PRO A HD2    1 
ATOM   1790  H HD3    . PRO A 1 113 ? -44.775 9.407   -32.020 1.00 59.43  ? 113 PRO A HD3    1 
ATOM   1791  N N      . GLY A 1 114 ? -48.433 5.347   -31.280 1.00 44.14  ? 114 GLY A N      1 
ATOM   1792  C CA     . GLY A 1 114 ? -49.563 4.562   -31.746 1.00 42.47  ? 114 GLY A CA     1 
ATOM   1793  C C      . GLY A 1 114 ? -49.213 3.551   -32.826 1.00 43.77  ? 114 GLY A C      1 
ATOM   1794  O O      . GLY A 1 114 ? -50.065 2.767   -33.240 1.00 47.18  ? 114 GLY A O      1 
ATOM   1795  H H      . GLY A 1 114 ? -47.985 4.969   -30.651 1.00 52.97  ? 114 GLY A H      1 
ATOM   1796  H HA2    . GLY A 1 114 ? -49.941 4.078   -30.995 1.00 50.97  ? 114 GLY A HA2    1 
ATOM   1797  H HA3    . GLY A 1 114 ? -50.247 5.154   -32.096 1.00 50.97  ? 114 GLY A HA3    1 
ATOM   1798  N N      . GLN A 1 115 ? -47.970 3.572   -33.296 1.00 44.44  ? 115 GLN A N      1 
ATOM   1799  C CA     . GLN A 1 115 ? -47.512 2.598   -34.288 1.00 39.04  ? 115 GLN A CA     1 
ATOM   1800  C C      . GLN A 1 115 ? -47.103 1.270   -33.647 1.00 36.42  ? 115 GLN A C      1 
ATOM   1801  O O      . GLN A 1 115 ? -47.056 1.145   -32.424 1.00 38.09  ? 115 GLN A O      1 
ATOM   1802  C CB     . GLN A 1 115 ? -46.341 3.165   -35.089 1.00 36.70  ? 115 GLN A CB     1 
ATOM   1803  C CG     . GLN A 1 115 ? -46.747 4.193   -36.130 1.00 38.83  ? 115 GLN A CG     1 
ATOM   1804  C CD     . GLN A 1 115 ? -45.597 4.583   -37.023 1.00 39.72  ? 115 GLN A CD     1 
ATOM   1805  O OE1    . GLN A 1 115 ? -44.548 5.012   -36.544 1.00 46.23  ? 115 GLN A OE1    1 
ATOM   1806  N NE2    . GLN A 1 115 ? -45.777 4.421   -38.331 1.00 44.98  ? 115 GLN A NE2    1 
ATOM   1807  H H      . GLN A 1 115 ? -47.369 4.139   -33.059 1.00 53.32  ? 115 GLN A H      1 
ATOM   1808  H HA     . GLN A 1 115 ? -48.234 2.418   -34.910 1.00 46.84  ? 115 GLN A HA     1 
ATOM   1809  H HB2    . GLN A 1 115 ? -45.721 3.590   -34.477 1.00 44.04  ? 115 GLN A HB2    1 
ATOM   1810  H HB3    . GLN A 1 115 ? -45.897 2.438   -35.552 1.00 44.04  ? 115 GLN A HB3    1 
ATOM   1811  H HG2    . GLN A 1 115 ? -47.449 3.822   -36.687 1.00 46.59  ? 115 GLN A HG2    1 
ATOM   1812  H HG3    . GLN A 1 115 ? -47.065 4.992   -35.681 1.00 46.59  ? 115 GLN A HG3    1 
ATOM   1813  H HE21   . GLN A 1 115 ? -46.521 4.108   -38.627 1.00 53.97  ? 115 GLN A HE21   1 
ATOM   1814  H HE22   . GLN A 1 115 ? -45.149 4.629   -38.880 1.00 53.97  ? 115 GLN A HE22   1 
ATOM   1815  N N      . TYR A 1 116 ? -46.812 0.280   -34.487 1.00 33.58  ? 116 TYR A N      1 
ATOM   1816  C CA     . TYR A 1 116 ? -46.372 -1.028  -34.022 1.00 37.26  ? 116 TYR A CA     1 
ATOM   1817  C C      . TYR A 1 116 ? -44.939 -1.312  -34.460 1.00 35.91  ? 116 TYR A C      1 
ATOM   1818  O O      . TYR A 1 116 ? -44.511 -0.885  -35.530 1.00 33.50  ? 116 TYR A O      1 
ATOM   1819  C CB     . TYR A 1 116 ? -47.286 -2.134  -34.554 1.00 39.83  ? 116 TYR A CB     1 
ATOM   1820  C CG     . TYR A 1 116 ? -48.706 -2.080  -34.043 1.00 42.16  ? 116 TYR A CG     1 
ATOM   1821  C CD1    . TYR A 1 116 ? -49.067 -2.727  -32.870 1.00 40.77  ? 116 TYR A CD1    1 
ATOM   1822  C CD2    . TYR A 1 116 ? -49.690 -1.392  -34.742 1.00 46.49  ? 116 TYR A CD2    1 
ATOM   1823  C CE1    . TYR A 1 116 ? -50.367 -2.685  -32.400 1.00 51.13  ? 116 TYR A CE1    1 
ATOM   1824  C CE2    . TYR A 1 116 ? -50.994 -1.344  -34.279 1.00 49.39  ? 116 TYR A CE2    1 
ATOM   1825  C CZ     . TYR A 1 116 ? -51.327 -1.993  -33.110 1.00 53.23  ? 116 TYR A CZ     1 
ATOM   1826  O OH     . TYR A 1 116 ? -52.624 -1.945  -32.648 1.00 54.73  ? 116 TYR A OH     1 
ATOM   1827  H H      . TYR A 1 116 ? -46.863 0.344   -35.343 1.00 40.30  ? 116 TYR A H      1 
ATOM   1828  H HA     . TYR A 1 116 ? -46.399 -1.062  -33.054 1.00 44.71  ? 116 TYR A HA     1 
ATOM   1829  H HB2    . TYR A 1 116 ? -47.320 -2.069  -35.521 1.00 47.79  ? 116 TYR A HB2    1 
ATOM   1830  H HB3    . TYR A 1 116 ? -46.914 -2.993  -34.298 1.00 47.79  ? 116 TYR A HB3    1 
ATOM   1831  H HD1    . TYR A 1 116 ? -48.423 -3.195  -32.389 1.00 48.92  ? 116 TYR A HD1    1 
ATOM   1832  H HD2    . TYR A 1 116 ? -49.468 -0.953  -35.532 1.00 55.78  ? 116 TYR A HD2    1 
ATOM   1833  H HE1    . TYR A 1 116 ? -50.593 -3.122  -31.611 1.00 61.36  ? 116 TYR A HE1    1 
ATOM   1834  H HE2    . TYR A 1 116 ? -51.642 -0.878  -34.756 1.00 59.27  ? 116 TYR A HE2    1 
ATOM   1835  H HH     . TYR A 1 116 ? -53.100 -1.494  -33.173 1.00 65.68  ? 116 TYR A HH     1 
ATOM   1836  N N      . VAL A 1 117 ? -44.207 -2.032  -33.620 1.00 32.06  ? 117 VAL A N      1 
ATOM   1837  C CA     . VAL A 1 117 ? -42.926 -2.607  -34.018 1.00 33.35  ? 117 VAL A CA     1 
ATOM   1838  C C      . VAL A 1 117 ? -43.034 -4.104  -33.813 1.00 32.83  ? 117 VAL A C      1 
ATOM   1839  O O      . VAL A 1 117 ? -43.416 -4.560  -32.738 1.00 33.50  ? 117 VAL A O      1 
ATOM   1840  C CB     . VAL A 1 117 ? -41.738 -2.037  -33.211 1.00 31.68  ? 117 VAL A CB     1 
ATOM   1841  C CG1    . VAL A 1 117 ? -40.457 -2.810  -33.523 1.00 32.43  ? 117 VAL A CG1    1 
ATOM   1842  C CG2    . VAL A 1 117 ? -41.550 -0.560  -33.524 1.00 31.18  ? 117 VAL A CG2    1 
ATOM   1843  H H      . VAL A 1 117 ? -44.430 -2.204  -32.808 1.00 38.47  ? 117 VAL A H      1 
ATOM   1844  H HA     . VAL A 1 117 ? -42.762 -2.442  -34.959 1.00 40.02  ? 117 VAL A HA     1 
ATOM   1845  H HB     . VAL A 1 117 ? -41.923 -2.126  -32.263 1.00 38.02  ? 117 VAL A HB     1 
ATOM   1846  H HG11   . VAL A 1 117 ? -39.696 -2.292  -33.217 1.00 38.92  ? 117 VAL A HG11   1 
ATOM   1847  H HG12   . VAL A 1 117 ? -40.480 -3.664  -33.064 1.00 38.92  ? 117 VAL A HG12   1 
ATOM   1848  H HG13   . VAL A 1 117 ? -40.397 -2.948  -34.481 1.00 38.92  ? 117 VAL A HG13   1 
ATOM   1849  H HG21   . VAL A 1 117 ? -40.805 -0.220  -33.005 1.00 37.41  ? 117 VAL A HG21   1 
ATOM   1850  H HG22   . VAL A 1 117 ? -41.367 -0.459  -34.471 1.00 37.41  ? 117 VAL A HG22   1 
ATOM   1851  H HG23   . VAL A 1 117 ? -42.361 -0.082  -33.290 1.00 37.41  ? 117 VAL A HG23   1 
ATOM   1852  N N      . ALA A 1 118 ? -42.719 -4.857  -34.858 1.00 28.53  ? 118 ALA A N      1 
ATOM   1853  C CA     . ALA A 1 118 ? -42.791 -6.304  -34.813 1.00 29.60  ? 118 ALA A CA     1 
ATOM   1854  C C      . ALA A 1 118 ? -41.395 -6.876  -34.973 1.00 30.91  ? 118 ALA A C      1 
ATOM   1855  O O      . ALA A 1 118 ? -40.614 -6.398  -35.787 1.00 29.38  ? 118 ALA A O      1 
ATOM   1856  C CB     . ALA A 1 118 ? -43.715 -6.825  -35.893 1.00 35.73  ? 118 ALA A CB     1 
ATOM   1857  H H      . ALA A 1 118 ? -42.457 -4.546  -35.616 1.00 34.23  ? 118 ALA A H      1 
ATOM   1858  H HA     . ALA A 1 118 ? -43.138 -6.583  -33.957 1.00 35.52  ? 118 ALA A HA     1 
ATOM   1859  H HB1    . ALA A 1 118 ? -43.755 -7.792  -35.834 1.00 42.88  ? 118 ALA A HB1    1 
ATOM   1860  H HB2    . ALA A 1 118 ? -44.598 -6.448  -35.758 1.00 42.88  ? 118 ALA A HB2    1 
ATOM   1861  H HB3    . ALA A 1 118 ? -43.370 -6.559  -36.760 1.00 42.88  ? 118 ALA A HB3    1 
ATOM   1862  N N      . GLY A 1 119 ? -41.076 -7.892  -34.184 1.00 32.31  ? 119 GLY A N      1 
ATOM   1863  C CA     . GLY A 1 119 ? -39.763 -8.500  -34.258 1.00 35.68  ? 119 GLY A CA     1 
ATOM   1864  C C      . GLY A 1 119 ? -39.759 -9.932  -33.786 1.00 32.03  ? 119 GLY A C      1 
ATOM   1865  O O      . GLY A 1 119 ? -40.742 -10.425 -33.222 1.00 29.67  ? 119 GLY A O      1 
ATOM   1866  H H      . GLY A 1 119 ? -41.601 -8.245  -33.601 1.00 38.77  ? 119 GLY A H      1 
ATOM   1867  H HA2    . GLY A 1 119 ? -39.446 -8.485  -35.174 1.00 42.82  ? 119 GLY A HA2    1 
ATOM   1868  H HA3    . GLY A 1 119 ? -39.143 -7.995  -33.710 1.00 42.82  ? 119 GLY A HA3    1 
ATOM   1869  N N      . ASN A 1 120 ? -38.638 -10.602 -34.022 1.00 25.65  ? 120 ASN A N      1 
ATOM   1870  C CA     . ASN A 1 120 ? -38.465 -11.970 -33.560 1.00 29.07  ? 120 ASN A CA     1 
ATOM   1871  C C      . ASN A 1 120 ? -37.996 -11.979 -32.110 1.00 31.56  ? 120 ASN A C      1 
ATOM   1872  O O      . ASN A 1 120 ? -36.798 -11.943 -31.825 1.00 28.59  ? 120 ASN A O      1 
ATOM   1873  C CB     . ASN A 1 120 ? -37.491 -12.729 -34.470 1.00 29.28  ? 120 ASN A CB     1 
ATOM   1874  C CG     . ASN A 1 120 ? -36.202 -11.963 -34.748 1.00 24.89  ? 120 ASN A CG     1 
ATOM   1875  O OD1    . ASN A 1 120 ? -36.112 -10.755 -34.524 1.00 27.16  ? 120 ASN A OD1    1 
ATOM   1876  N ND2    . ASN A 1 120 ? -35.205 -12.671 -35.270 1.00 24.86  ? 120 ASN A ND2    1 
ATOM   1877  H H      . ASN A 1 120 ? -37.964 -10.281 -34.448 1.00 30.78  ? 120 ASN A H      1 
ATOM   1878  H HA     . ASN A 1 120 ? -39.319 -12.427 -33.600 1.00 34.88  ? 120 ASN A HA     1 
ATOM   1879  H HB2    . ASN A 1 120 ? -37.253 -13.568 -34.045 1.00 35.14  ? 120 ASN A HB2    1 
ATOM   1880  H HB3    . ASN A 1 120 ? -37.925 -12.901 -35.320 1.00 35.14  ? 120 ASN A HB3    1 
ATOM   1881  H HD21   . ASN A 1 120 ? -34.454 -12.291 -35.447 1.00 29.84  ? 120 ASN A HD21   1 
ATOM   1882  H HD22   . ASN A 1 120 ? -35.311 -13.509 -35.430 1.00 29.84  ? 120 ASN A HD22   1 
ATOM   1883  N N      . MET A 1 121 ? -38.968 -12.027 -31.201 1.00 27.90  ? 121 MET A N      1 
ATOM   1884  C CA     . MET A 1 121 ? -38.732 -11.840 -29.773 1.00 34.10  ? 121 MET A CA     1 
ATOM   1885  C C      . MET A 1 121 ? -38.077 -10.475 -29.538 1.00 34.82  ? 121 MET A C      1 
ATOM   1886  O O      . MET A 1 121 ? -38.119 -9.606  -30.408 1.00 31.43  ? 121 MET A O      1 
ATOM   1887  C CB     . MET A 1 121 ? -37.893 -12.990 -29.212 1.00 37.35  ? 121 MET A CB     1 
ATOM   1888  C CG     . MET A 1 121 ? -38.682 -14.288 -29.137 1.00 35.43  ? 121 MET A CG     1 
ATOM   1889  S SD     . MET A 1 121 ? -37.712 -15.747 -28.712 1.00 35.77  ? 121 MET A SD     1 
ATOM   1890  C CE     . MET A 1 121 ? -38.983 -16.770 -27.975 1.00 46.28  ? 121 MET A CE     1 
ATOM   1891  H H      . MET A 1 121 ? -39.794 -12.170 -31.394 1.00 33.48  ? 121 MET A H      1 
ATOM   1892  H HA     . MET A 1 121 ? -39.587 -11.853 -29.315 1.00 40.92  ? 121 MET A HA     1 
ATOM   1893  H HB2    . MET A 1 121 ? -37.119 -13.142 -29.773 1.00 44.82  ? 121 MET A HB2    1 
ATOM   1894  H HB3    . MET A 1 121 ? -37.609 -12.774 -28.311 1.00 44.82  ? 121 MET A HB3    1 
ATOM   1895  H HG2    . MET A 1 121 ? -39.377 -14.191 -28.468 1.00 42.51  ? 121 MET A HG2    1 
ATOM   1896  H HG3    . MET A 1 121 ? -39.083 -14.444 -30.004 1.00 42.51  ? 121 MET A HG3    1 
ATOM   1897  H HE1    . MET A 1 121 ? -38.586 -17.606 -27.685 1.00 55.53  ? 121 MET A HE1    1 
ATOM   1898  H HE2    . MET A 1 121 ? -39.363 -16.302 -27.215 1.00 55.53  ? 121 MET A HE2    1 
ATOM   1899  H HE3    . MET A 1 121 ? -39.672 -16.942 -28.636 1.00 55.53  ? 121 MET A HE3    1 
ATOM   1900  N N      . TYR A 1 122 ? -37.506 -10.268 -28.358 1.00 34.30  ? 122 TYR A N      1 
ATOM   1901  C CA     . TYR A 1 122 ? -37.038 -8.939  -27.984 1.00 34.63  ? 122 TYR A CA     1 
ATOM   1902  C C      . TYR A 1 122 ? -35.918 -8.983  -26.963 1.00 28.52  ? 122 TYR A C      1 
ATOM   1903  O O      . TYR A 1 122 ? -35.632 -10.027 -26.376 1.00 28.78  ? 122 TYR A O      1 
ATOM   1904  C CB     . TYR A 1 122 ? -38.193 -8.118  -27.406 1.00 34.41  ? 122 TYR A CB     1 
ATOM   1905  C CG     . TYR A 1 122 ? -38.677 -8.666  -26.085 1.00 39.00  ? 122 TYR A CG     1 
ATOM   1906  C CD1    . TYR A 1 122 ? -39.550 -9.746  -26.041 1.00 40.06  ? 122 TYR A CD1    1 
ATOM   1907  C CD2    . TYR A 1 122 ? -38.241 -8.124  -24.881 1.00 40.26  ? 122 TYR A CD2    1 
ATOM   1908  C CE1    . TYR A 1 122 ? -39.986 -10.263 -24.837 1.00 40.98  ? 122 TYR A CE1    1 
ATOM   1909  C CE2    . TYR A 1 122 ? -38.672 -8.633  -23.671 1.00 39.50  ? 122 TYR A CE2    1 
ATOM   1910  C CZ     . TYR A 1 122 ? -39.545 -9.702  -23.655 1.00 41.99  ? 122 TYR A CZ     1 
ATOM   1911  O OH     . TYR A 1 122 ? -39.976 -10.213 -22.456 1.00 43.46  ? 122 TYR A OH     1 
ATOM   1912  H H      . TYR A 1 122 ? -37.379 -10.870 -27.758 1.00 41.16  ? 122 TYR A H      1 
ATOM   1913  H HA     . TYR A 1 122 ? -36.703 -8.483  -28.771 1.00 41.56  ? 122 TYR A HA     1 
ATOM   1914  H HB2    . TYR A 1 122 ? -37.896 -7.207  -27.260 1.00 41.29  ? 122 TYR A HB2    1 
ATOM   1915  H HB3    . TYR A 1 122 ? -38.936 -8.132  -28.029 1.00 41.29  ? 122 TYR A HB3    1 
ATOM   1916  H HD1    . TYR A 1 122 ? -39.848 -10.125 -26.836 1.00 48.07  ? 122 TYR A HD1    1 
ATOM   1917  H HD2    . TYR A 1 122 ? -37.653 -7.404  -24.890 1.00 48.31  ? 122 TYR A HD2    1 
ATOM   1918  H HE1    . TYR A 1 122 ? -40.574 -10.983 -24.822 1.00 49.18  ? 122 TYR A HE1    1 
ATOM   1919  H HE2    . TYR A 1 122 ? -38.376 -8.258  -22.873 1.00 47.41  ? 122 TYR A HE2    1 
ATOM   1920  H HH     . TYR A 1 122 ? -39.634 -9.783  -21.821 1.00 52.15  ? 122 TYR A HH     1 
ATOM   1921  N N      . PHE A 1 123 ? -35.302 -7.824  -26.762 1.00 31.83  ? 123 PHE A N      1 
ATOM   1922  C CA     . PHE A 1 123 ? -34.353 -7.603  -25.684 1.00 33.92  ? 123 PHE A CA     1 
ATOM   1923  C C      . PHE A 1 123 ? -34.834 -6.384  -24.888 1.00 31.03  ? 123 PHE A C      1 
ATOM   1924  O O      . PHE A 1 123 ? -35.431 -5.466  -25.451 1.00 28.39  ? 123 PHE A O      1 
ATOM   1925  C CB     . PHE A 1 123 ? -32.935 -7.397  -26.233 1.00 33.11  ? 123 PHE A CB     1 
ATOM   1926  C CG     . PHE A 1 123 ? -31.906 -7.158  -25.165 1.00 28.37  ? 123 PHE A CG     1 
ATOM   1927  C CD1    . PHE A 1 123 ? -31.461 -8.199  -24.370 1.00 34.68  ? 123 PHE A CD1    1 
ATOM   1928  C CD2    . PHE A 1 123 ? -31.390 -5.890  -24.950 1.00 31.86  ? 123 PHE A CD2    1 
ATOM   1929  C CE1    . PHE A 1 123 ? -30.524 -7.984  -23.379 1.00 37.54  ? 123 PHE A CE1    1 
ATOM   1930  C CE2    . PHE A 1 123 ? -30.451 -5.671  -23.962 1.00 31.31  ? 123 PHE A CE2    1 
ATOM   1931  C CZ     . PHE A 1 123 ? -30.018 -6.721  -23.175 1.00 33.92  ? 123 PHE A CZ     1 
ATOM   1932  H H      . PHE A 1 123 ? -35.423 -7.130  -27.255 1.00 38.20  ? 123 PHE A H      1 
ATOM   1933  H HA     . PHE A 1 123 ? -34.343 -8.369  -25.090 1.00 40.71  ? 123 PHE A HA     1 
ATOM   1934  H HB2    . PHE A 1 123 ? -32.672 -8.189  -26.727 1.00 39.73  ? 123 PHE A HB2    1 
ATOM   1935  H HB3    . PHE A 1 123 ? -32.936 -6.627  -26.822 1.00 39.73  ? 123 PHE A HB3    1 
ATOM   1936  H HD1    . PHE A 1 123 ? -31.802 -9.054  -24.501 1.00 41.62  ? 123 PHE A HD1    1 
ATOM   1937  H HD2    . PHE A 1 123 ? -31.680 -5.179  -25.475 1.00 38.23  ? 123 PHE A HD2    1 
ATOM   1938  H HE1    . PHE A 1 123 ? -30.232 -8.693  -22.852 1.00 45.05  ? 123 PHE A HE1    1 
ATOM   1939  H HE2    . PHE A 1 123 ? -30.110 -4.817  -23.826 1.00 37.57  ? 123 PHE A HE2    1 
ATOM   1940  H HZ     . PHE A 1 123 ? -29.383 -6.575  -22.511 1.00 40.71  ? 123 PHE A HZ     1 
ATOM   1941  N N      . THR A 1 124 ? -34.577 -6.384  -23.584 1.00 28.99  ? 124 THR A N      1 
ATOM   1942  C CA     . THR A 1 124 ? -35.150 -5.387  -22.680 1.00 30.77  ? 124 THR A CA     1 
ATOM   1943  C C      . THR A 1 124 ? -34.924 -3.941  -23.131 1.00 31.69  ? 124 THR A C      1 
ATOM   1944  O O      . THR A 1 124 ? -35.881 -3.184  -23.253 1.00 31.28  ? 124 THR A O      1 
ATOM   1945  C CB     . THR A 1 124 ? -34.590 -5.568  -21.262 1.00 31.97  ? 124 THR A CB     1 
ATOM   1946  O OG1    . THR A 1 124 ? -34.976 -6.860  -20.775 1.00 36.24  ? 124 THR A OG1    1 
ATOM   1947  C CG2    . THR A 1 124 ? -35.128 -4.497  -20.315 1.00 34.26  ? 124 THR A CG2    1 
ATOM   1948  H H      . THR A 1 124 ? -34.069 -6.956  -23.192 1.00 34.79  ? 124 THR A H      1 
ATOM   1949  H HA     . THR A 1 124 ? -36.108 -5.530  -22.635 1.00 36.92  ? 124 THR A HA     1 
ATOM   1950  H HB     . THR A 1 124 ? -33.622 -5.504  -21.284 1.00 38.37  ? 124 THR A HB     1 
ATOM   1951  H HG1    . THR A 1 124 ? -34.677 -6.975  -19.999 1.00 43.49  ? 124 THR A HG1    1 
ATOM   1952  H HG21   . THR A 1 124 ? -34.996 -4.775  -19.395 1.00 41.11  ? 124 THR A HG21   1 
ATOM   1953  H HG22   . THR A 1 124 ? -34.663 -3.658  -20.459 1.00 41.11  ? 124 THR A HG22   1 
ATOM   1954  H HG23   . THR A 1 124 ? -36.076 -4.365  -20.469 1.00 41.11  ? 124 THR A HG23   1 
ATOM   1955  N N      . THR A 1 125 ? -33.678 -3.553  -23.387 1.00 27.53  ? 125 THR A N      1 
ATOM   1956  C CA     . THR A 1 125 ? -33.389 -2.156  -23.707 1.00 29.89  ? 125 THR A CA     1 
ATOM   1957  C C      . THR A 1 125 ? -34.015 -1.747  -25.043 1.00 31.21  ? 125 THR A C      1 
ATOM   1958  O O      . THR A 1 125 ? -34.588 -0.662  -25.159 1.00 29.70  ? 125 THR A O      1 
ATOM   1959  C CB     . THR A 1 125 ? -31.870 -1.877  -23.758 1.00 31.39  ? 125 THR A CB     1 
ATOM   1960  O OG1    . THR A 1 125 ? -31.267 -2.670  -24.785 1.00 27.03  ? 125 THR A OG1    1 
ATOM   1961  C CG2    . THR A 1 125 ? -31.221 -2.198  -22.428 1.00 28.42  ? 125 THR A CG2    1 
ATOM   1962  H H      . THR A 1 125 ? -32.990 -4.070  -23.383 1.00 33.03  ? 125 THR A H      1 
ATOM   1963  H HA     . THR A 1 125 ? -33.771 -1.592  -23.016 1.00 35.87  ? 125 THR A HA     1 
ATOM   1964  H HB     . THR A 1 125 ? -31.723 -0.938  -23.950 1.00 37.67  ? 125 THR A HB     1 
ATOM   1965  H HG1    . THR A 1 125 ? -31.522 -2.406  -25.540 1.00 32.43  ? 125 THR A HG1    1 
ATOM   1966  H HG21   . THR A 1 125 ? -30.276 -1.981  -22.460 1.00 34.10  ? 125 THR A HG21   1 
ATOM   1967  H HG22   . THR A 1 125 ? -31.639 -1.681  -21.722 1.00 34.10  ? 125 THR A HG22   1 
ATOM   1968  H HG23   . THR A 1 125 ? -31.322 -3.142  -22.229 1.00 34.10  ? 125 THR A HG23   1 
ATOM   1969  N N      . THR A 1 126 ? -33.896 -2.620  -26.040 1.00 26.95  ? 126 THR A N      1 
ATOM   1970  C CA     . THR A 1 126 ? -34.458 -2.377  -27.366 1.00 31.02  ? 126 THR A CA     1 
ATOM   1971  C C      . THR A 1 126 ? -35.962 -2.119  -27.287 1.00 30.84  ? 126 THR A C      1 
ATOM   1972  O O      . THR A 1 126 ? -36.473 -1.141  -27.843 1.00 30.60  ? 126 THR A O      1 
ATOM   1973  C CB     . THR A 1 126 ? -34.212 -3.578  -28.303 1.00 32.36  ? 126 THR A CB     1 
ATOM   1974  O OG1    . THR A 1 126 ? -32.921 -4.146  -28.039 1.00 33.37  ? 126 THR A OG1    1 
ATOM   1975  C CG2    . THR A 1 126 ? -34.327 -3.167  -29.774 1.00 33.11  ? 126 THR A CG2    1 
ATOM   1976  H H      . THR A 1 126 ? -33.487 -3.373  -25.972 1.00 32.33  ? 126 THR A H      1 
ATOM   1977  H HA     . THR A 1 126 ? -34.035 -1.596  -27.755 1.00 37.23  ? 126 THR A HA     1 
ATOM   1978  H HB     . THR A 1 126 ? -34.887 -4.246  -28.124 1.00 38.83  ? 126 THR A HB     1 
ATOM   1979  H HG1    . THR A 1 126 ? -32.337 -3.755  -28.496 1.00 40.05  ? 126 THR A HG1    1 
ATOM   1980  H HG21   . THR A 1 126 ? -34.167 -3.934  -30.346 1.00 39.73  ? 126 THR A HG21   1 
ATOM   1981  H HG22   . THR A 1 126 ? -35.215 -2.821  -29.953 1.00 39.73  ? 126 THR A HG22   1 
ATOM   1982  H HG23   . THR A 1 126 ? -33.674 -2.480  -29.978 1.00 39.73  ? 126 THR A HG23   1 
ATOM   1983  N N      . ARG A 1 127 ? -36.663 -3.000  -26.582 1.00 30.00  ? 127 ARG A N      1 
ATOM   1984  C CA     . ARG A 1 127 ? -38.112 -2.893  -26.452 1.00 32.85  ? 127 ARG A CA     1 
ATOM   1985  C C      . ARG A 1 127 ? -38.504 -1.654  -25.653 1.00 32.44  ? 127 ARG A C      1 
ATOM   1986  O O      . ARG A 1 127 ? -39.486 -0.990  -25.975 1.00 30.50  ? 127 ARG A O      1 
ATOM   1987  C CB     . ARG A 1 127 ? -38.680 -4.148  -25.795 1.00 34.36  ? 127 ARG A CB     1 
ATOM   1988  C CG     . ARG A 1 127 ? -40.192 -4.138  -25.654 1.00 38.99  ? 127 ARG A CG     1 
ATOM   1989  C CD     . ARG A 1 127 ? -40.712 -5.523  -25.333 1.00 39.04  ? 127 ARG A CD     1 
ATOM   1990  N NE     . ARG A 1 127 ? -42.157 -5.527  -25.138 1.00 46.86  ? 127 ARG A NE     1 
ATOM   1991  C CZ     . ARG A 1 127 ? -42.870 -6.610  -24.848 1.00 48.76  ? 127 ARG A CZ     1 
ATOM   1992  N NH1    . ARG A 1 127 ? -42.275 -7.788  -24.719 1.00 40.46  ? 127 ARG A NH1    1 
ATOM   1993  N NH2    . ARG A 1 127 ? -44.183 -6.512  -24.689 1.00 51.12  ? 127 ARG A NH2    1 
ATOM   1994  H H      . ARG A 1 127 ? -36.322 -3.672  -26.167 1.00 36.00  ? 127 ARG A H      1 
ATOM   1995  H HA     . ARG A 1 127 ? -38.503 -2.815  -27.336 1.00 39.42  ? 127 ARG A HA     1 
ATOM   1996  H HB2    . ARG A 1 127 ? -38.438 -4.919  -26.332 1.00 41.23  ? 127 ARG A HB2    1 
ATOM   1997  H HB3    . ARG A 1 127 ? -38.300 -4.234  -24.907 1.00 41.23  ? 127 ARG A HB3    1 
ATOM   1998  H HG2    . ARG A 1 127 ? -40.445 -3.542  -24.932 1.00 46.79  ? 127 ARG A HG2    1 
ATOM   1999  H HG3    . ARG A 1 127 ? -40.592 -3.847  -26.488 1.00 46.79  ? 127 ARG A HG3    1 
ATOM   2000  H HD2    . ARG A 1 127 ? -40.504 -6.120  -26.068 1.00 46.85  ? 127 ARG A HD2    1 
ATOM   2001  H HD3    . ARG A 1 127 ? -40.295 -5.839  -24.516 1.00 46.85  ? 127 ARG A HD3    1 
ATOM   2002  H HE     . ARG A 1 127 ? -42.575 -4.780  -25.216 1.00 56.23  ? 127 ARG A HE     1 
ATOM   2003  H HH11   . ARG A 1 127 ? -41.424 -7.858  -24.821 1.00 48.55  ? 127 ARG A HH11   1 
ATOM   2004  H HH12   . ARG A 1 127 ? -42.742 -8.485  -24.532 1.00 48.55  ? 127 ARG A HH12   1 
ATOM   2005  H HH21   . ARG A 1 127 ? -44.571 -5.749  -24.773 1.00 61.35  ? 127 ARG A HH21   1 
ATOM   2006  H HH22   . ARG A 1 127 ? -44.647 -7.212  -24.502 1.00 61.35  ? 127 ARG A HH22   1 
ATOM   2007  N N      . TYR A 1 128 ? -37.734 -1.346  -24.613 1.00 29.63  ? 128 TYR A N      1 
ATOM   2008  C CA     . TYR A 1 128 ? -37.998 -0.165  -23.800 1.00 30.99  ? 128 TYR A CA     1 
ATOM   2009  C C      . TYR A 1 128 ? -38.075 1.079   -24.670 1.00 32.19  ? 128 TYR A C      1 
ATOM   2010  O O      . TYR A 1 128 ? -39.036 1.836   -24.593 1.00 32.76  ? 128 TYR A O      1 
ATOM   2011  C CB     . TYR A 1 128 ? -36.924 0.035   -22.730 1.00 31.70  ? 128 TYR A CB     1 
ATOM   2012  C CG     . TYR A 1 128 ? -37.048 1.375   -22.031 1.00 33.19  ? 128 TYR A CG     1 
ATOM   2013  C CD1    . TYR A 1 128 ? -37.851 1.523   -20.907 1.00 36.95  ? 128 TYR A CD1    1 
ATOM   2014  C CD2    . TYR A 1 128 ? -36.374 2.497   -22.508 1.00 33.35  ? 128 TYR A CD2    1 
ATOM   2015  C CE1    . TYR A 1 128 ? -37.976 2.750   -20.270 1.00 38.18  ? 128 TYR A CE1    1 
ATOM   2016  C CE2    . TYR A 1 128 ? -36.495 3.729   -21.878 1.00 38.69  ? 128 TYR A CE2    1 
ATOM   2017  C CZ     . TYR A 1 128 ? -37.296 3.849   -20.760 1.00 45.32  ? 128 TYR A CZ     1 
ATOM   2018  O OH     . TYR A 1 128 ? -37.413 5.075   -20.134 1.00 52.30  ? 128 TYR A OH     1 
ATOM   2019  H H      . TYR A 1 128 ? -37.053 -1.805  -24.358 1.00 35.55  ? 128 TYR A H      1 
ATOM   2020  H HA     . TYR A 1 128 ? -38.852 -0.273  -23.353 1.00 37.19  ? 128 TYR A HA     1 
ATOM   2021  H HB2    . TYR A 1 128 ? -37.009 -0.662  -22.061 1.00 38.03  ? 128 TYR A HB2    1 
ATOM   2022  H HB3    . TYR A 1 128 ? -36.049 -0.007  -23.146 1.00 38.03  ? 128 TYR A HB3    1 
ATOM   2023  H HD1    . TYR A 1 128 ? -38.312 0.787   -20.575 1.00 44.33  ? 128 TYR A HD1    1 
ATOM   2024  H HD2    . TYR A 1 128 ? -35.835 2.420   -23.262 1.00 40.02  ? 128 TYR A HD2    1 
ATOM   2025  H HE1    . TYR A 1 128 ? -38.516 2.832   -19.517 1.00 45.82  ? 128 TYR A HE1    1 
ATOM   2026  H HE2    . TYR A 1 128 ? -36.037 4.469   -22.206 1.00 46.43  ? 128 TYR A HE2    1 
ATOM   2027  H HH     . TYR A 1 128 ? -36.949 5.648   -20.536 1.00 62.76  ? 128 TYR A HH     1 
ATOM   2028  N N      . HIS A 1 129 ? -37.055 1.282   -25.494 1.00 28.40  ? 129 HIS A N      1 
ATOM   2029  C CA     . HIS A 1 129 ? -36.982 2.474   -26.328 1.00 33.36  ? 129 HIS A CA     1 
ATOM   2030  C C      . HIS A 1 129 ? -38.073 2.481   -27.390 1.00 31.35  ? 129 HIS A C      1 
ATOM   2031  O O      . HIS A 1 129 ? -38.560 3.540   -27.769 1.00 33.47  ? 129 HIS A O      1 
ATOM   2032  C CB     . HIS A 1 129 ? -35.602 2.587   -26.973 1.00 27.86  ? 129 HIS A CB     1 
ATOM   2033  C CG     . HIS A 1 129 ? -34.520 2.910   -25.991 1.00 32.81  ? 129 HIS A CG     1 
ATOM   2034  N ND1    . HIS A 1 129 ? -34.475 4.106   -25.308 1.00 28.33  ? 129 HIS A ND1    1 
ATOM   2035  C CD2    . HIS A 1 129 ? -33.469 2.181   -25.545 1.00 29.09  ? 129 HIS A CD2    1 
ATOM   2036  C CE1    . HIS A 1 129 ? -33.431 4.109   -24.499 1.00 33.52  ? 129 HIS A CE1    1 
ATOM   2037  N NE2    . HIS A 1 129 ? -32.806 2.951   -24.621 1.00 31.94  ? 129 HIS A NE2    1 
ATOM   2038  H H      . HIS A 1 129 ? -36.391 0.744   -25.589 1.00 34.07  ? 129 HIS A H      1 
ATOM   2039  H HA     . HIS A 1 129 ? -37.111 3.255   -25.767 1.00 40.03  ? 129 HIS A HA     1 
ATOM   2040  H HB2    . HIS A 1 129 ? -35.381 1.742   -27.394 1.00 33.44  ? 129 HIS A HB2    1 
ATOM   2041  H HB3    . HIS A 1 129 ? -35.622 3.293   -27.638 1.00 33.44  ? 129 HIS A HB3    1 
ATOM   2042  H HD2    . HIS A 1 129 ? -33.236 1.323   -25.818 1.00 34.90  ? 129 HIS A HD2    1 
ATOM   2043  H HE1    . HIS A 1 129 ? -33.181 4.806   -23.936 1.00 40.22  ? 129 HIS A HE1    1 
ATOM   2044  H HE2    . HIS A 1 129 ? -32.095 2.720   -24.196 1.00 38.33  ? 129 HIS A HE2    1 
ATOM   2045  N N      . GLN A 1 130 ? -38.467 1.306   -27.864 1.00 30.03  ? 130 GLN A N      1 
ATOM   2046  C CA     . GLN A 1 130 ? -39.577 1.232   -28.810 1.00 34.00  ? 130 GLN A CA     1 
ATOM   2047  C C      . GLN A 1 130 ? -40.873 1.689   -28.140 1.00 31.80  ? 130 GLN A C      1 
ATOM   2048  O O      . GLN A 1 130 ? -41.612 2.501   -28.690 1.00 33.20  ? 130 GLN A O      1 
ATOM   2049  C CB     . GLN A 1 130 ? -39.734 -0.186  -29.357 1.00 29.47  ? 130 GLN A CB     1 
ATOM   2050  C CG     . GLN A 1 130 ? -38.629 -0.610  -30.323 1.00 31.38  ? 130 GLN A CG     1 
ATOM   2051  C CD     . GLN A 1 130 ? -38.549 -2.116  -30.495 1.00 32.56  ? 130 GLN A CD     1 
ATOM   2052  O OE1    . GLN A 1 130 ? -39.332 -2.861  -29.909 1.00 33.20  ? 130 GLN A OE1    1 
ATOM   2053  N NE2    . GLN A 1 130 ? -37.593 -2.572  -31.299 1.00 32.19  ? 130 GLN A NE2    1 
ATOM   2054  H H      . GLN A 1 130 ? -38.117 0.548   -27.660 1.00 36.03  ? 130 GLN A H      1 
ATOM   2055  H HA     . GLN A 1 130 ? -39.398 1.825   -29.557 1.00 40.80  ? 130 GLN A HA     1 
ATOM   2056  H HB2    . GLN A 1 130 ? -39.731 -0.803  -28.609 1.00 35.37  ? 130 GLN A HB2    1 
ATOM   2057  H HB3    . GLN A 1 130 ? -40.579 -0.247  -29.829 1.00 35.37  ? 130 GLN A HB3    1 
ATOM   2058  H HG2    . GLN A 1 130 ? -38.802 -0.217  -31.193 1.00 37.66  ? 130 GLN A HG2    1 
ATOM   2059  H HG3    . GLN A 1 130 ? -37.775 -0.301  -29.983 1.00 37.66  ? 130 GLN A HG3    1 
ATOM   2060  H HE21   . GLN A 1 130 ? -37.058 -2.021  -31.686 1.00 38.62  ? 130 GLN A HE21   1 
ATOM   2061  H HE22   . GLN A 1 130 ? -37.510 -3.418  -31.432 1.00 38.62  ? 130 GLN A HE22   1 
ATOM   2062  N N      . GLU A 1 131 ? -41.130 1.182   -26.938 1.00 30.18  ? 131 GLU A N      1 
ATOM   2063  C CA     . GLU A 1 131 ? -42.362 1.501   -26.226 1.00 33.59  ? 131 GLU A CA     1 
ATOM   2064  C C      . GLU A 1 131 ? -42.346 2.938   -25.699 1.00 39.39  ? 131 GLU A C      1 
ATOM   2065  O O      . GLU A 1 131 ? -43.377 3.613   -25.690 1.00 35.99  ? 131 GLU A O      1 
ATOM   2066  C CB     . GLU A 1 131 ? -42.582 0.502   -25.085 1.00 35.98  ? 131 GLU A CB     1 
ATOM   2067  C CG     . GLU A 1 131 ? -42.860 -0.922  -25.579 1.00 33.10  ? 131 GLU A CG     1 
ATOM   2068  C CD     . GLU A 1 131 ? -42.982 -1.944  -24.451 1.00 42.60  ? 131 GLU A CD     1 
ATOM   2069  O OE1    . GLU A 1 131 ? -43.507 -3.053  -24.703 1.00 41.61  ? 131 GLU A OE1    1 
ATOM   2070  O OE2    . GLU A 1 131 ? -42.545 -1.648  -23.319 1.00 43.83  ? 131 GLU A OE2    1 
ATOM   2071  H H      . GLU A 1 131 ? -40.606 0.650   -26.512 1.00 36.21  ? 131 GLU A H      1 
ATOM   2072  H HA     . GLU A 1 131 ? -43.107 1.420   -26.840 1.00 40.31  ? 131 GLU A HA     1 
ATOM   2073  H HB2    . GLU A 1 131 ? -41.785 0.478   -24.532 1.00 43.18  ? 131 GLU A HB2    1 
ATOM   2074  H HB3    . GLU A 1 131 ? -43.343 0.789   -24.557 1.00 43.18  ? 131 GLU A HB3    1 
ATOM   2075  H HG2    . GLU A 1 131 ? -43.694 -0.925  -26.074 1.00 39.72  ? 131 GLU A HG2    1 
ATOM   2076  H HG3    . GLU A 1 131 ? -42.132 -1.202  -26.156 1.00 39.72  ? 131 GLU A HG3    1 
ATOM   2077  N N      . LYS A 1 132 ? -41.173 3.407   -25.282 1.00 36.99  ? 132 LYS A N      1 
ATOM   2078  C CA     . LYS A 1 132 ? -41.017 4.772   -24.777 1.00 37.13  ? 132 LYS A CA     1 
ATOM   2079  C C      . LYS A 1 132 ? -41.434 5.788   -25.834 1.00 39.79  ? 132 LYS A C      1 
ATOM   2080  O O      . LYS A 1 132 ? -41.943 6.859   -25.509 1.00 42.12  ? 132 LYS A O      1 
ATOM   2081  C CB     . LYS A 1 132 ? -39.561 5.015   -24.346 1.00 42.46  ? 132 LYS A CB     1 
ATOM   2082  C CG     . LYS A 1 132 ? -39.214 6.447   -23.939 1.00 48.31  ? 132 LYS A CG     1 
ATOM   2083  C CD     . LYS A 1 132 ? -39.798 6.812   -22.587 1.00 53.70  ? 132 LYS A CD     1 
ATOM   2084  C CE     . LYS A 1 132 ? -39.419 8.234   -22.188 1.00 61.12  ? 132 LYS A CE     1 
ATOM   2085  N NZ     . LYS A 1 132 ? -40.014 8.630   -20.878 1.00 64.99  ? 132 LYS A NZ     1 
ATOM   2086  H H      . LYS A 1 132 ? -40.444 2.951   -25.281 1.00 44.39  ? 132 LYS A H      1 
ATOM   2087  H HA     . LYS A 1 132 ? -41.586 4.892   -24.001 1.00 44.56  ? 132 LYS A HA     1 
ATOM   2088  H HB2    . LYS A 1 132 ? -39.368 4.444   -23.586 1.00 50.95  ? 132 LYS A HB2    1 
ATOM   2089  H HB3    . LYS A 1 132 ? -38.980 4.775   -25.085 1.00 50.95  ? 132 LYS A HB3    1 
ATOM   2090  H HG2    . LYS A 1 132 ? -38.249 6.529   -23.877 1.00 57.97  ? 132 LYS A HG2    1 
ATOM   2091  H HG3    . LYS A 1 132 ? -39.554 7.072   -24.597 1.00 57.97  ? 132 LYS A HG3    1 
ATOM   2092  H HD2    . LYS A 1 132 ? -40.765 6.755   -22.629 1.00 64.45  ? 132 LYS A HD2    1 
ATOM   2093  H HD3    . LYS A 1 132 ? -39.454 6.204   -21.914 1.00 64.45  ? 132 LYS A HD3    1 
ATOM   2094  H HE2    . LYS A 1 132 ? -38.454 8.296   -22.112 1.00 73.34  ? 132 LYS A HE2    1 
ATOM   2095  H HE3    . LYS A 1 132 ? -39.741 8.850   -22.864 1.00 73.34  ? 132 LYS A HE3    1 
ATOM   2096  H HZ1    . LYS A 1 132 ? -39.774 9.463   -20.675 1.00 77.99  ? 132 LYS A HZ1    1 
ATOM   2097  H HZ2    . LYS A 1 132 ? -40.902 8.587   -20.922 1.00 77.99  ? 132 LYS A HZ2    1 
ATOM   2098  H HZ3    . LYS A 1 132 ? -39.729 8.082   -20.237 1.00 77.99  ? 132 LYS A HZ3    1 
ATOM   2099  N N      . ASN A 1 133 ? -41.213 5.442   -27.100 1.00 36.17  ? 133 ASN A N      1 
ATOM   2100  C CA     . ASN A 1 133 ? -41.535 6.327   -28.213 1.00 38.76  ? 133 ASN A CA     1 
ATOM   2101  C C      . ASN A 1 133 ? -42.933 6.079   -28.772 1.00 40.65  ? 133 ASN A C      1 
ATOM   2102  O O      . ASN A 1 133 ? -43.314 6.646   -29.803 1.00 40.01  ? 133 ASN A O      1 
ATOM   2103  C CB     . ASN A 1 133 ? -40.483 6.177   -29.313 1.00 36.77  ? 133 ASN A CB     1 
ATOM   2104  C CG     . ASN A 1 133 ? -39.214 6.936   -28.992 1.00 43.70  ? 133 ASN A CG     1 
ATOM   2105  O OD1    . ASN A 1 133 ? -39.157 8.153   -29.163 1.00 40.33  ? 133 ASN A OD1    1 
ATOM   2106  N ND2    . ASN A 1 133 ? -38.200 6.229   -28.490 1.00 35.49  ? 133 ASN A ND2    1 
ATOM   2107  H H      . ASN A 1 133 ? -40.873 4.690   -27.342 1.00 43.40  ? 133 ASN A H      1 
ATOM   2108  H HA     . ASN A 1 133 ? -41.502 7.246   -27.905 1.00 46.51  ? 133 ASN A HA     1 
ATOM   2109  H HB2    . ASN A 1 133 ? -40.257 5.239   -29.411 1.00 44.13  ? 133 ASN A HB2    1 
ATOM   2110  H HB3    . ASN A 1 133 ? -40.837 6.524   -30.147 1.00 44.13  ? 133 ASN A HB3    1 
ATOM   2111  H HD21   . ASN A 1 133 ? -37.460 6.619   -28.293 1.00 42.59  ? 133 ASN A HD21   1 
ATOM   2112  H HD22   . ASN A 1 133 ? -38.287 5.383   -28.363 1.00 42.59  ? 133 ASN A HD22   1 
ATOM   2113  N N      . GLY A 1 134 ? -43.689 5.229   -28.083 1.00 37.06  ? 134 GLY A N      1 
ATOM   2114  C CA     . GLY A 1 134 ? -45.108 5.078   -28.341 1.00 42.05  ? 134 GLY A CA     1 
ATOM   2115  C C      . GLY A 1 134 ? -45.463 3.896   -29.217 1.00 40.25  ? 134 GLY A C      1 
ATOM   2116  O O      . GLY A 1 134 ? -46.562 3.848   -29.768 1.00 40.89  ? 134 GLY A O      1 
ATOM   2117  H H      . GLY A 1 134 ? -43.398 4.721   -27.454 1.00 44.47  ? 134 GLY A H      1 
ATOM   2118  H HA2    . GLY A 1 134 ? -45.570 4.971   -27.495 1.00 50.45  ? 134 GLY A HA2    1 
ATOM   2119  H HA3    . GLY A 1 134 ? -45.445 5.882   -28.765 1.00 50.45  ? 134 GLY A HA3    1 
ATOM   2120  N N      . ALA A 1 135 ? -44.551 2.938   -29.348 1.00 36.86  ? 135 ALA A N      1 
ATOM   2121  C CA     . ALA A 1 135 ? -44.846 1.744   -30.133 1.00 36.70  ? 135 ALA A CA     1 
ATOM   2122  C C      . ALA A 1 135 ? -45.396 0.639   -29.248 1.00 36.08  ? 135 ALA A C      1 
ATOM   2123  O O      . ALA A 1 135 ? -45.129 0.588   -28.049 1.00 35.73  ? 135 ALA A O      1 
ATOM   2124  C CB     . ALA A 1 135 ? -43.609 1.256   -30.877 1.00 38.40  ? 135 ALA A CB     1 
ATOM   2125  H H      . ALA A 1 135 ? -43.765 2.953   -28.998 1.00 44.23  ? 135 ALA A H      1 
ATOM   2126  H HA     . ALA A 1 135 ? -45.515 1.959   -30.796 1.00 44.04  ? 135 ALA A HA     1 
ATOM   2127  H HB1    . ALA A 1 135 ? -43.843 0.466   -31.388 1.00 46.08  ? 135 ALA A HB1    1 
ATOM   2128  H HB2    . ALA A 1 135 ? -43.302 1.954   -31.474 1.00 46.08  ? 135 ALA A HB2    1 
ATOM   2129  H HB3    . ALA A 1 135 ? -42.917 1.038   -30.234 1.00 46.08  ? 135 ALA A HB3    1 
ATOM   2130  N N      . THR A 1 136 ? -46.191 -0.228  -29.859 1.00 36.09  ? 136 THR A N      1 
ATOM   2131  C CA     . THR A 1 136 ? -46.607 -1.472  -29.244 1.00 37.20  ? 136 THR A CA     1 
ATOM   2132  C C      . THR A 1 136 ? -45.795 -2.584  -29.884 1.00 35.74  ? 136 THR A C      1 
ATOM   2133  O O      . THR A 1 136 ? -45.748 -2.697  -31.112 1.00 34.63  ? 136 THR A O      1 
ATOM   2134  C CB     . THR A 1 136 ? -48.115 -1.726  -29.433 1.00 39.01  ? 136 THR A CB     1 
ATOM   2135  O OG1    . THR A 1 136 ? -48.852 -0.830  -28.593 1.00 40.26  ? 136 THR A OG1    1 
ATOM   2136  C CG2    . THR A 1 136 ? -48.480 -3.160  -29.076 1.00 35.90  ? 136 THR A CG2    1 
ATOM   2137  H H      . THR A 1 136 ? -46.509 -0.112  -30.650 1.00 43.30  ? 136 THR A H      1 
ATOM   2138  H HA     . THR A 1 136 ? -46.416 -1.458  -28.294 1.00 44.63  ? 136 THR A HA     1 
ATOM   2139  H HB     . THR A 1 136 ? -48.355 -1.570  -30.360 1.00 46.81  ? 136 THR A HB     1 
ATOM   2140  H HG1    . THR A 1 136 ? -49.676 -0.960  -28.688 1.00 48.31  ? 136 THR A HG1    1 
ATOM   2141  H HG21   . THR A 1 136 ? -49.437 -3.230  -28.933 1.00 43.08  ? 136 THR A HG21   1 
ATOM   2142  H HG22   . THR A 1 136 ? -48.226 -3.759  -29.795 1.00 43.08  ? 136 THR A HG22   1 
ATOM   2143  H HG23   . THR A 1 136 ? -48.021 -3.426  -28.264 1.00 43.08  ? 136 THR A HG23   1 
ATOM   2144  N N      . PHE A 1 137 ? -45.142 -3.396  -29.062 1.00 37.36  ? 137 PHE A N      1 
ATOM   2145  C CA     . PHE A 1 137 ? -44.333 -4.484  -29.593 1.00 36.15  ? 137 PHE A CA     1 
ATOM   2146  C C      . PHE A 1 137 ? -45.159 -5.725  -29.888 1.00 33.42  ? 137 PHE A C      1 
ATOM   2147  O O      . PHE A 1 137 ? -45.937 -6.173  -29.046 1.00 35.38  ? 137 PHE A O      1 
ATOM   2148  C CB     . PHE A 1 137 ? -43.211 -4.862  -28.632 1.00 38.07  ? 137 PHE A CB     1 
ATOM   2149  C CG     . PHE A 1 137 ? -42.429 -6.054  -29.089 1.00 35.00  ? 137 PHE A CG     1 
ATOM   2150  C CD1    . PHE A 1 137 ? -41.508 -5.932  -30.116 1.00 35.35  ? 137 PHE A CD1    1 
ATOM   2151  C CD2    . PHE A 1 137 ? -42.639 -7.300  -28.521 1.00 38.79  ? 137 PHE A CD2    1 
ATOM   2152  C CE1    . PHE A 1 137 ? -40.794 -7.030  -30.556 1.00 37.89  ? 137 PHE A CE1    1 
ATOM   2153  C CE2    . PHE A 1 137 ? -41.926 -8.404  -28.956 1.00 36.85  ? 137 PHE A CE2    1 
ATOM   2154  C CZ     . PHE A 1 137 ? -41.005 -8.268  -29.973 1.00 35.13  ? 137 PHE A CZ     1 
ATOM   2155  H H      . PHE A 1 137 ? -45.150 -3.340  -28.204 1.00 44.83  ? 137 PHE A H      1 
ATOM   2156  H HA     . PHE A 1 137 ? -43.920 -4.193  -30.418 1.00 43.37  ? 137 PHE A HA     1 
ATOM   2157  H HB2    . PHE A 1 137 ? -42.598 -4.114  -28.553 1.00 45.68  ? 137 PHE A HB2    1 
ATOM   2158  H HB3    . PHE A 1 137 ? -43.594 -5.070  -27.765 1.00 45.68  ? 137 PHE A HB3    1 
ATOM   2159  H HD1    . PHE A 1 137 ? -41.364 -5.102  -30.509 1.00 42.42  ? 137 PHE A HD1    1 
ATOM   2160  H HD2    . PHE A 1 137 ? -43.259 -7.394  -27.835 1.00 46.55  ? 137 PHE A HD2    1 
ATOM   2161  H HE1    . PHE A 1 137 ? -40.172 -6.937  -31.241 1.00 45.47  ? 137 PHE A HE1    1 
ATOM   2162  H HE2    . PHE A 1 137 ? -42.068 -9.235  -28.564 1.00 44.22  ? 137 PHE A HE2    1 
ATOM   2163  H HZ     . PHE A 1 137 ? -40.524 -9.008  -30.266 1.00 42.15  ? 137 PHE A HZ     1 
ATOM   2164  N N      . ILE A 1 138 ? -44.960 -6.280  -31.083 1.00 31.19  ? 138 ILE A N      1 
ATOM   2165  C CA     . ILE A 1 138 ? -45.614 -7.517  -31.504 1.00 33.65  ? 138 ILE A CA     1 
ATOM   2166  C C      . ILE A 1 138 ? -44.591 -8.609  -31.817 1.00 31.72  ? 138 ILE A C      1 
ATOM   2167  O O      . ILE A 1 138 ? -43.740 -8.450  -32.690 1.00 27.64  ? 138 ILE A O      1 
ATOM   2168  C CB     . ILE A 1 138 ? -46.488 -7.294  -32.755 1.00 34.55  ? 138 ILE A CB     1 
ATOM   2169  C CG1    . ILE A 1 138 ? -47.469 -6.140  -32.532 1.00 35.72  ? 138 ILE A CG1    1 
ATOM   2170  C CG2    . ILE A 1 138 ? -47.227 -8.581  -33.132 1.00 34.82  ? 138 ILE A CG2    1 
ATOM   2171  C CD1    . ILE A 1 138 ? -48.417 -6.342  -31.359 1.00 36.33  ? 138 ILE A CD1    1 
ATOM   2172  H H      . ILE A 1 138 ? -44.438 -5.950  -31.681 1.00 37.43  ? 138 ILE A H      1 
ATOM   2173  H HA     . ILE A 1 138 ? -46.186 -7.844  -30.793 1.00 40.38  ? 138 ILE A HA     1 
ATOM   2174  H HB     . ILE A 1 138 ? -45.904 -7.055  -33.492 1.00 41.46  ? 138 ILE A HB     1 
ATOM   2175  H HG12   . ILE A 1 138 ? -46.966 -5.327  -32.369 1.00 42.86  ? 138 ILE A HG12   1 
ATOM   2176  H HG13   . ILE A 1 138 ? -48.009 -6.034  -33.331 1.00 42.86  ? 138 ILE A HG13   1 
ATOM   2177  H HG21   . ILE A 1 138 ? -47.945 -8.363  -33.745 1.00 41.78  ? 138 ILE A HG21   1 
ATOM   2178  H HG22   . ILE A 1 138 ? -46.605 -9.192  -33.556 1.00 41.78  ? 138 ILE A HG22   1 
ATOM   2179  H HG23   . ILE A 1 138 ? -47.592 -8.982  -32.328 1.00 41.78  ? 138 ILE A HG23   1 
ATOM   2180  H HD11   . ILE A 1 138 ? -49.046 -5.604  -31.334 1.00 43.60  ? 138 ILE A HD11   1 
ATOM   2181  H HD12   . ILE A 1 138 ? -48.894 -7.178  -31.478 1.00 43.60  ? 138 ILE A HD12   1 
ATOM   2182  H HD13   . ILE A 1 138 ? -47.907 -6.367  -30.536 1.00 43.60  ? 138 ILE A HD13   1 
ATOM   2183  N N      . ASP A 1 139 ? -44.696 -9.729  -31.116 1.00 32.24  ? 139 ASP A N      1 
ATOM   2184  C CA     . ASP A 1 139 ? -43.816 -10.862 -31.361 1.00 32.23  ? 139 ASP A CA     1 
ATOM   2185  C C      . ASP A 1 139 ? -44.285 -11.633 -32.589 1.00 36.83  ? 139 ASP A C      1 
ATOM   2186  O O      . ASP A 1 139 ? -45.427 -12.091 -32.638 1.00 31.39  ? 139 ASP A O      1 
ATOM   2187  C CB     . ASP A 1 139 ? -43.779 -11.777 -30.138 1.00 33.86  ? 139 ASP A CB     1 
ATOM   2188  C CG     . ASP A 1 139 ? -42.687 -12.828 -30.221 1.00 38.44  ? 139 ASP A CG     1 
ATOM   2189  O OD1    . ASP A 1 139 ? -41.892 -12.804 -31.186 1.00 32.72  ? 139 ASP A OD1    1 
ATOM   2190  O OD2    . ASP A 1 139 ? -42.616 -13.671 -29.299 1.00 39.96  ? 139 ASP A OD2    1 
ATOM   2191  H H      . ASP A 1 139 ? -45.271 -9.859  -30.490 1.00 38.69  ? 139 ASP A H      1 
ATOM   2192  H HA     . ASP A 1 139 ? -42.917 -10.539 -31.527 1.00 38.68  ? 139 ASP A HA     1 
ATOM   2193  H HB2    . ASP A 1 139 ? -43.618 -11.240 -29.347 1.00 40.63  ? 139 ASP A HB2    1 
ATOM   2194  H HB3    . ASP A 1 139 ? -44.631 -12.235 -30.061 1.00 40.63  ? 139 ASP A HB3    1 
ATOM   2195  N N      . ILE A 1 140 ? -43.401 -11.769 -33.576 1.00 30.48  ? 140 ILE A N      1 
ATOM   2196  C CA     . ILE A 1 140 ? -43.713 -12.511 -34.792 1.00 27.87  ? 140 ILE A CA     1 
ATOM   2197  C C      . ILE A 1 140 ? -42.694 -13.616 -35.074 1.00 27.86  ? 140 ILE A C      1 
ATOM   2198  O O      . ILE A 1 140 ? -42.585 -14.101 -36.199 1.00 28.73  ? 140 ILE A O      1 
ATOM   2199  C CB     . ILE A 1 140 ? -43.791 -11.573 -36.011 1.00 25.54  ? 140 ILE A CB     1 
ATOM   2200  C CG1    . ILE A 1 140 ? -42.498 -10.752 -36.134 1.00 32.78  ? 140 ILE A CG1    1 
ATOM   2201  C CG2    . ILE A 1 140 ? -45.005 -10.670 -35.884 1.00 31.95  ? 140 ILE A CG2    1 
ATOM   2202  C CD1    . ILE A 1 140 ? -42.378 -9.988  -37.422 1.00 30.00  ? 140 ILE A CD1    1 
ATOM   2203  H H      . ILE A 1 140 ? -42.608 -11.438 -33.564 1.00 36.57  ? 140 ILE A H      1 
ATOM   2204  H HA     . ILE A 1 140 ? -44.578 -12.937 -34.699 1.00 33.44  ? 140 ILE A HA     1 
ATOM   2205  H HB     . ILE A 1 140 ? -43.895 -12.108 -36.813 1.00 30.65  ? 140 ILE A HB     1 
ATOM   2206  H HG12   . ILE A 1 140 ? -42.466 -10.110 -35.407 1.00 39.34  ? 140 ILE A HG12   1 
ATOM   2207  H HG13   . ILE A 1 140 ? -41.736 -11.349 -36.077 1.00 39.34  ? 140 ILE A HG13   1 
ATOM   2208  H HG21   . ILE A 1 140 ? -45.082 -10.129 -36.685 1.00 38.34  ? 140 ILE A HG21   1 
ATOM   2209  H HG22   . ILE A 1 140 ? -45.797 -11.220 -35.780 1.00 38.34  ? 140 ILE A HG22   1 
ATOM   2210  H HG23   . ILE A 1 140 ? -44.894 -10.100 -35.107 1.00 38.34  ? 140 ILE A HG23   1 
ATOM   2211  H HD11   . ILE A 1 140 ? -41.501 -9.576  -37.464 1.00 36.00  ? 140 ILE A HD11   1 
ATOM   2212  H HD12   . ILE A 1 140 ? -42.492 -10.602 -38.164 1.00 36.00  ? 140 ILE A HD12   1 
ATOM   2213  H HD13   . ILE A 1 140 ? -43.066 -9.305  -37.450 1.00 36.00  ? 140 ILE A HD13   1 
ATOM   2214  N N      . VAL A 1 141 ? -41.957 -14.027 -34.050 1.00 26.55  ? 141 VAL A N      1 
ATOM   2215  C CA     . VAL A 1 141 ? -41.053 -15.158 -34.193 1.00 26.94  ? 141 VAL A CA     1 
ATOM   2216  C C      . VAL A 1 141 ? -41.871 -16.432 -34.413 1.00 30.70  ? 141 VAL A C      1 
ATOM   2217  O O      . VAL A 1 141 ? -43.040 -16.502 -34.031 1.00 28.16  ? 141 VAL A O      1 
ATOM   2218  C CB     . VAL A 1 141 ? -40.132 -15.321 -32.950 1.00 28.34  ? 141 VAL A CB     1 
ATOM   2219  C CG1    . VAL A 1 141 ? -40.913 -15.872 -31.745 1.00 28.82  ? 141 VAL A CG1    1 
ATOM   2220  C CG2    . VAL A 1 141 ? -38.941 -16.210 -33.278 1.00 30.66  ? 141 VAL A CG2    1 
ATOM   2221  H H      . VAL A 1 141 ? -41.961 -13.672 -33.267 1.00 31.86  ? 141 VAL A H      1 
ATOM   2222  H HA     . VAL A 1 141 ? -40.490 -15.021 -34.971 1.00 32.33  ? 141 VAL A HA     1 
ATOM   2223  H HB     . VAL A 1 141 ? -39.788 -14.449 -32.702 1.00 34.00  ? 141 VAL A HB     1 
ATOM   2224  H HG11   . VAL A 1 141 ? -40.350 -15.837 -30.958 1.00 34.59  ? 141 VAL A HG11   1 
ATOM   2225  H HG12   . VAL A 1 141 ? -41.707 -15.332 -31.609 1.00 34.59  ? 141 VAL A HG12   1 
ATOM   2226  H HG13   . VAL A 1 141 ? -41.166 -16.791 -31.920 1.00 34.59  ? 141 VAL A HG13   1 
ATOM   2227  H HG21   . VAL A 1 141 ? -38.328 -16.204 -32.526 1.00 36.80  ? 141 VAL A HG21   1 
ATOM   2228  H HG22   . VAL A 1 141 ? -39.255 -17.113 -33.440 1.00 36.80  ? 141 VAL A HG22   1 
ATOM   2229  H HG23   . VAL A 1 141 ? -38.498 -15.865 -34.069 1.00 36.80  ? 141 VAL A HG23   1 
ATOM   2230  N N      . ARG A 1 142 ? -41.259 -17.426 -35.049 1.00 29.24  ? 142 ARG A N      1 
ATOM   2231  C CA     . ARG A 1 142 ? -41.888 -18.728 -35.233 1.00 33.08  ? 142 ARG A CA     1 
ATOM   2232  C C      . ARG A 1 142 ? -42.237 -19.349 -33.884 1.00 35.20  ? 142 ARG A C      1 
ATOM   2233  O O      . ARG A 1 142 ? -41.523 -19.146 -32.898 1.00 27.05  ? 142 ARG A O      1 
ATOM   2234  C CB     . ARG A 1 142 ? -40.964 -19.653 -36.027 1.00 29.25  ? 142 ARG A CB     1 
ATOM   2235  C CG     . ARG A 1 142 ? -39.573 -19.818 -35.411 1.00 34.14  ? 142 ARG A CG     1 
ATOM   2236  C CD     . ARG A 1 142 ? -38.611 -20.495 -36.379 1.00 35.10  ? 142 ARG A CD     1 
ATOM   2237  N NE     . ARG A 1 142 ? -39.032 -21.847 -36.724 1.00 38.04  ? 142 ARG A NE     1 
ATOM   2238  C CZ     . ARG A 1 142 ? -38.337 -22.682 -37.491 1.00 44.51  ? 142 ARG A CZ     1 
ATOM   2239  N NH1    . ARG A 1 142 ? -37.167 -22.316 -38.005 1.00 40.13  ? 142 ARG A NH1    1 
ATOM   2240  N NH2    . ARG A 1 142 ? -38.818 -23.892 -37.742 1.00 46.79  ? 142 ARG A NH2    1 
ATOM   2241  H H      . ARG A 1 142 ? -40.472 -17.366 -35.390 1.00 35.09  ? 142 ARG A H      1 
ATOM   2242  H HA     . ARG A 1 142 ? -42.711 -18.620 -35.732 1.00 39.70  ? 142 ARG A HA     1 
ATOM   2243  H HB2    . ARG A 1 142 ? -41.372 -20.530 -36.081 1.00 35.10  ? 142 ARG A HB2    1 
ATOM   2244  H HB3    . ARG A 1 142 ? -40.851 -19.289 -36.919 1.00 35.10  ? 142 ARG A HB3    1 
ATOM   2245  H HG2    . ARG A 1 142 ? -39.209 -18.948 -35.185 1.00 40.97  ? 142 ARG A HG2    1 
ATOM   2246  H HG3    . ARG A 1 142 ? -39.640 -20.369 -34.616 1.00 40.97  ? 142 ARG A HG3    1 
ATOM   2247  H HD2    . ARG A 1 142 ? -38.583 -19.980 -37.197 1.00 42.12  ? 142 ARG A HD2    1 
ATOM   2248  H HD3    . ARG A 1 142 ? -37.729 -20.541 -35.978 1.00 42.12  ? 142 ARG A HD3    1 
ATOM   2249  H HE     . ARG A 1 142 ? -39.783 -22.124 -36.409 1.00 45.65  ? 142 ARG A HE     1 
ATOM   2250  H HH11   . ARG A 1 142 ? -36.850 -21.533 -37.846 1.00 48.15  ? 142 ARG A HH11   1 
ATOM   2251  H HH12   . ARG A 1 142 ? -36.726 -22.864 -38.499 1.00 48.15  ? 142 ARG A HH12   1 
ATOM   2252  H HH21   . ARG A 1 142 ? -39.574 -24.131 -37.410 1.00 56.14  ? 142 ARG A HH21   1 
ATOM   2253  H HH22   . ARG A 1 142 ? -38.373 -24.438 -38.236 1.00 56.14  ? 142 ARG A HH22   1 
ATOM   2254  N N      . ASP A 1 143 ? -43.341 -20.095 -33.838 1.00 35.45  ? 143 ASP A N      1 
ATOM   2255  C CA     . ASP A 1 143 ? -43.796 -20.713 -32.591 1.00 34.38  ? 143 ASP A CA     1 
ATOM   2256  C C      . ASP A 1 143 ? -42.719 -21.592 -31.959 1.00 32.95  ? 143 ASP A C      1 
ATOM   2257  O O      . ASP A 1 143 ? -42.608 -21.650 -30.736 1.00 33.73  ? 143 ASP A O      1 
ATOM   2258  C CB     . ASP A 1 143 ? -45.060 -21.554 -32.820 1.00 38.55  ? 143 ASP A CB     1 
ATOM   2259  C CG     . ASP A 1 143 ? -46.293 -20.710 -33.099 1.00 41.37  ? 143 ASP A CG     1 
ATOM   2260  O OD1    . ASP A 1 143 ? -46.343 -19.542 -32.661 1.00 43.00  ? 143 ASP A OD1    1 
ATOM   2261  O OD2    . ASP A 1 143 ? -47.220 -21.226 -33.757 1.00 53.11  ? 143 ASP A OD2    1 
ATOM   2262  H H      . ASP A 1 143 ? -43.845 -20.259 -34.515 1.00 42.53  ? 143 ASP A H      1 
ATOM   2263  H HA     . ASP A 1 143 ? -44.011 -20.013 -31.955 1.00 41.26  ? 143 ASP A HA     1 
ATOM   2264  H HB2    . ASP A 1 143 ? -44.917 -22.136 -33.583 1.00 46.26  ? 143 ASP A HB2    1 
ATOM   2265  H HB3    . ASP A 1 143 ? -45.234 -22.084 -32.027 1.00 46.26  ? 143 ASP A HB3    1 
ATOM   2266  N N      . GLU A 1 144 ? -41.928 -22.259 -32.797 1.00 30.68  ? 144 GLU A N      1 
ATOM   2267  C CA     . GLU A 1 144 ? -40.894 -23.179 -32.336 1.00 33.71  ? 144 GLU A CA     1 
ATOM   2268  C C      . GLU A 1 144 ? -39.908 -22.520 -31.378 1.00 33.87  ? 144 GLU A C      1 
ATOM   2269  O O      . GLU A 1 144 ? -39.314 -23.190 -30.532 1.00 33.10  ? 144 GLU A O      1 
ATOM   2270  C CB     . GLU A 1 144 ? -40.121 -23.760 -33.524 1.00 33.92  ? 144 GLU A CB     1 
ATOM   2271  C CG     . GLU A 1 144 ? -40.881 -24.798 -34.341 1.00 37.31  ? 144 GLU A CG     1 
ATOM   2272  C CD     . GLU A 1 144 ? -41.770 -24.194 -35.415 1.00 43.97  ? 144 GLU A CD     1 
ATOM   2273  O OE1    . GLU A 1 144 ? -41.780 -22.954 -35.576 1.00 42.00  ? 144 GLU A OE1    1 
ATOM   2274  O OE2    . GLU A 1 144 ? -42.463 -24.970 -36.106 1.00 51.76  ? 144 GLU A OE2    1 
ATOM   2275  H H      . GLU A 1 144 ? -41.973 -22.193 -33.653 1.00 36.81  ? 144 GLU A H      1 
ATOM   2276  H HA     . GLU A 1 144 ? -41.317 -23.915 -31.867 1.00 40.45  ? 144 GLU A HA     1 
ATOM   2277  H HB2    . GLU A 1 144 ? -39.862 -23.036 -34.114 1.00 40.71  ? 144 GLU A HB2    1 
ATOM   2278  H HB3    . GLU A 1 144 ? -39.323 -24.193 -33.182 1.00 40.71  ? 144 GLU A HB3    1 
ATOM   2279  H HG2    . GLU A 1 144 ? -40.242 -25.382 -34.778 1.00 44.78  ? 144 GLU A HG2    1 
ATOM   2280  H HG3    . GLU A 1 144 ? -41.445 -25.315 -33.745 1.00 44.78  ? 144 GLU A HG3    1 
ATOM   2281  N N      . ALA A 1 145 ? -39.733 -21.211 -31.520 1.00 31.80  ? 145 ALA A N      1 
ATOM   2282  C CA     . ALA A 1 145 ? -38.765 -20.474 -30.710 1.00 33.50  ? 145 ALA A CA     1 
ATOM   2283  C C      . ALA A 1 145 ? -39.147 -20.483 -29.238 1.00 33.22  ? 145 ALA A C      1 
ATOM   2284  O O      . ALA A 1 145 ? -38.293 -20.303 -28.367 1.00 33.88  ? 145 ALA A O      1 
ATOM   2285  C CB     . ALA A 1 145 ? -38.644 -19.047 -31.209 1.00 32.39  ? 145 ALA A CB     1 
ATOM   2286  H H      . ALA A 1 145 ? -40.163 -20.722 -32.081 1.00 38.15  ? 145 ALA A H      1 
ATOM   2287  H HA     . ALA A 1 145 ? -37.897 -20.894 -30.790 1.00 40.20  ? 145 ALA A HA     1 
ATOM   2288  H HB1    . ALA A 1 145 ? -37.947 -18.594 -30.708 1.00 38.87  ? 145 ALA A HB1    1 
ATOM   2289  H HB2    . ALA A 1 145 ? -38.420 -19.061 -32.152 1.00 38.87  ? 145 ALA A HB2    1 
ATOM   2290  H HB3    . ALA A 1 145 ? -39.493 -18.596 -31.080 1.00 38.87  ? 145 ALA A HB3    1 
ATOM   2291  N N      . HIS A 1 146 ? -40.430 -20.693 -28.963 1.00 34.00  ? 146 HIS A N      1 
ATOM   2292  C CA     . HIS A 1 146 ? -40.922 -20.706 -27.588 1.00 33.11  ? 146 HIS A CA     1 
ATOM   2293  C C      . HIS A 1 146 ? -40.936 -22.117 -26.993 1.00 36.24  ? 146 HIS A C      1 
ATOM   2294  O O      . HIS A 1 146 ? -41.401 -22.315 -25.874 1.00 37.65  ? 146 HIS A O      1 
ATOM   2295  C CB     . HIS A 1 146 ? -42.318 -20.092 -27.531 1.00 35.64  ? 146 HIS A CB     1 
ATOM   2296  C CG     . HIS A 1 146 ? -42.329 -18.617 -27.777 1.00 40.64  ? 146 HIS A CG     1 
ATOM   2297  N ND1    . HIS A 1 146 ? -42.752 -18.063 -28.968 1.00 40.39  ? 146 HIS A ND1    1 
ATOM   2298  C CD2    . HIS A 1 146 ? -41.954 -17.580 -26.993 1.00 39.07  ? 146 HIS A CD2    1 
ATOM   2299  C CE1    . HIS A 1 146 ? -42.644 -16.748 -28.902 1.00 41.13  ? 146 HIS A CE1    1 
ATOM   2300  N NE2    . HIS A 1 146 ? -42.161 -16.428 -27.713 1.00 46.51  ? 146 HIS A NE2    1 
ATOM   2301  H H      . HIS A 1 146 ? -41.039 -20.830 -29.554 1.00 40.81  ? 146 HIS A H      1 
ATOM   2302  H HA     . HIS A 1 146 ? -40.342 -20.159 -27.036 1.00 39.73  ? 146 HIS A HA     1 
ATOM   2303  H HB2    . HIS A 1 146 ? -42.873 -20.511 -28.208 1.00 42.77  ? 146 HIS A HB2    1 
ATOM   2304  H HB3    . HIS A 1 146 ? -42.696 -20.249 -26.652 1.00 42.77  ? 146 HIS A HB3    1 
ATOM   2305  H HD2    . HIS A 1 146 ? -41.621 -17.636 -26.126 1.00 46.89  ? 146 HIS A HD2    1 
ATOM   2306  H HE1    . HIS A 1 146 ? -42.869 -16.149 -29.577 1.00 49.36  ? 146 HIS A HE1    1 
ATOM   2307  H HE2    . HIS A 1 146 ? -42.004 -15.629 -27.435 1.00 55.81  ? 146 HIS A HE2    1 
ATOM   2308  N N      . ASP A 1 147 ? -40.423 -23.088 -27.742 1.00 35.16  ? 147 ASP A N      1 
ATOM   2309  C CA     . ASP A 1 147 ? -40.273 -24.460 -27.246 1.00 33.01  ? 147 ASP A CA     1 
ATOM   2310  C C      . ASP A 1 147 ? -38.808 -24.711 -26.919 1.00 32.32  ? 147 ASP A C      1 
ATOM   2311  O O      . ASP A 1 147 ? -38.022 -25.090 -27.787 1.00 30.26  ? 147 ASP A O      1 
ATOM   2312  C CB     . ASP A 1 147 ? -40.781 -25.467 -28.282 1.00 36.17  ? 147 ASP A CB     1 
ATOM   2313  C CG     . ASP A 1 147 ? -40.861 -26.892 -27.737 1.00 44.61  ? 147 ASP A CG     1 
ATOM   2314  O OD1    . ASP A 1 147 ? -40.128 -27.227 -26.779 1.00 36.06  ? 147 ASP A OD1    1 
ATOM   2315  O OD2    . ASP A 1 147 ? -41.660 -27.684 -28.282 1.00 39.98  ? 147 ASP A OD2    1 
ATOM   2316  H H      . ASP A 1 147 ? -40.150 -22.983 -28.550 1.00 42.20  ? 147 ASP A H      1 
ATOM   2317  H HA     . ASP A 1 147 ? -40.790 -24.580 -26.434 1.00 39.62  ? 147 ASP A HA     1 
ATOM   2318  H HB2    . ASP A 1 147 ? -41.672 -25.205 -28.563 1.00 43.40  ? 147 ASP A HB2    1 
ATOM   2319  H HB3    . ASP A 1 147 ? -40.182 -25.470 -29.045 1.00 43.40  ? 147 ASP A HB3    1 
ATOM   2320  N N      . ALA A 1 148 ? -38.448 -24.521 -25.656 1.00 32.51  ? 148 ALA A N      1 
ATOM   2321  C CA     . ALA A 1 148 ? -37.043 -24.471 -25.262 1.00 36.26  ? 148 ALA A CA     1 
ATOM   2322  C C      . ALA A 1 148 ? -36.335 -25.813 -25.412 1.00 31.99  ? 148 ALA A C      1 
ATOM   2323  O O      . ALA A 1 148 ? -35.109 -25.872 -25.379 1.00 38.80  ? 148 ALA A O      1 
ATOM   2324  C CB     . ALA A 1 148 ? -36.917 -23.977 -23.821 1.00 32.85  ? 148 ALA A CB     1 
ATOM   2325  H H      . ALA A 1 148 ? -38.999 -24.418 -25.004 1.00 39.01  ? 148 ALA A H      1 
ATOM   2326  H HA     . ALA A 1 148 ? -36.585 -23.833 -25.832 1.00 43.51  ? 148 ALA A HA     1 
ATOM   2327  H HB1    . ALA A 1 148 ? -35.978 -23.950 -23.578 1.00 39.42  ? 148 ALA A HB1    1 
ATOM   2328  H HB2    . ALA A 1 148 ? -37.301 -23.088 -23.758 1.00 39.42  ? 148 ALA A HB2    1 
ATOM   2329  H HB3    . ALA A 1 148 ? -37.394 -24.586 -23.236 1.00 39.42  ? 148 ALA A HB3    1 
ATOM   2330  N N      . GLY A 1 149 ? -37.098 -26.887 -25.573 1.00 31.37  ? 149 GLY A N      1 
ATOM   2331  C CA     . GLY A 1 149 ? -36.516 -28.211 -25.694 1.00 33.42  ? 149 GLY A CA     1 
ATOM   2332  C C      . GLY A 1 149 ? -36.356 -28.669 -27.131 1.00 36.43  ? 149 GLY A C      1 
ATOM   2333  O O      . GLY A 1 149 ? -35.643 -29.635 -27.412 1.00 35.86  ? 149 GLY A O      1 
ATOM   2334  H H      . GLY A 1 149 ? -37.957 -26.875 -25.615 1.00 37.64  ? 149 GLY A H      1 
ATOM   2335  H HA2    . GLY A 1 149 ? -35.645 -28.232 -25.268 1.00 40.10  ? 149 GLY A HA2    1 
ATOM   2336  H HA3    . GLY A 1 149 ? -37.088 -28.849 -25.239 1.00 40.10  ? 149 GLY A HA3    1 
ATOM   2337  N N      . LEU A 1 150 ? -37.012 -27.971 -28.048 1.00 33.29  ? 150 LEU A N      1 
ATOM   2338  C CA     . LEU A 1 150 ? -37.039 -28.401 -29.438 1.00 33.53  ? 150 LEU A CA     1 
ATOM   2339  C C      . LEU A 1 150 ? -35.745 -28.054 -30.185 1.00 34.74  ? 150 LEU A C      1 
ATOM   2340  O O      . LEU A 1 150 ? -35.374 -26.884 -30.307 1.00 33.89  ? 150 LEU A O      1 
ATOM   2341  C CB     . LEU A 1 150 ? -38.242 -27.779 -30.146 1.00 31.13  ? 150 LEU A CB     1 
ATOM   2342  C CG     . LEU A 1 150 ? -38.564 -28.331 -31.534 1.00 36.83  ? 150 LEU A CG     1 
ATOM   2343  C CD1    . LEU A 1 150 ? -38.834 -29.832 -31.497 1.00 42.85  ? 150 LEU A CD1    1 
ATOM   2344  C CD2    . LEU A 1 150 ? -39.755 -27.593 -32.111 1.00 42.03  ? 150 LEU A CD2    1 
ATOM   2345  H H      . LEU A 1 150 ? -37.449 -27.247 -27.894 1.00 39.95  ? 150 LEU A H      1 
ATOM   2346  H HA     . LEU A 1 150 ? -37.144 -29.365 -29.461 1.00 40.24  ? 150 LEU A HA     1 
ATOM   2347  H HB2    . LEU A 1 150 ? -39.026 -27.917 -29.592 1.00 37.36  ? 150 LEU A HB2    1 
ATOM   2348  H HB3    . LEU A 1 150 ? -38.080 -26.828 -30.244 1.00 37.36  ? 150 LEU A HB3    1 
ATOM   2349  H HG     . LEU A 1 150 ? -37.805 -28.176 -32.116 1.00 44.19  ? 150 LEU A HG     1 
ATOM   2350  H HD11   . LEU A 1 150 ? -39.214 -30.104 -32.347 1.00 51.42  ? 150 LEU A HD11   1 
ATOM   2351  H HD12   . LEU A 1 150 ? -37.999 -30.299 -31.344 1.00 51.42  ? 150 LEU A HD12   1 
ATOM   2352  H HD13   . LEU A 1 150 ? -39.459 -30.023 -30.780 1.00 51.42  ? 150 LEU A HD13   1 
ATOM   2353  H HD21   . LEU A 1 150 ? -39.948 -27.946 -32.994 1.00 50.44  ? 150 LEU A HD21   1 
ATOM   2354  H HD22   . LEU A 1 150 ? -40.519 -27.723 -31.528 1.00 50.44  ? 150 LEU A HD22   1 
ATOM   2355  H HD23   . LEU A 1 150 ? -39.542 -26.649 -32.172 1.00 50.44  ? 150 LEU A HD23   1 
ATOM   2356  N N      . ASP A 1 151 ? -35.066 -29.087 -30.679 1.00 34.06  ? 151 ASP A N      1 
ATOM   2357  C CA     . ASP A 1 151 ? -33.830 -28.915 -31.440 1.00 36.70  ? 151 ASP A CA     1 
ATOM   2358  C C      . ASP A 1 151 ? -34.114 -28.803 -32.939 1.00 37.37  ? 151 ASP A C      1 
ATOM   2359  O O      . ASP A 1 151 ? -34.174 -29.809 -33.643 1.00 41.24  ? 151 ASP A O      1 
ATOM   2360  C CB     . ASP A 1 151 ? -32.874 -30.082 -31.173 1.00 38.66  ? 151 ASP A CB     1 
ATOM   2361  C CG     . ASP A 1 151 ? -31.478 -29.840 -31.727 1.00 44.42  ? 151 ASP A CG     1 
ATOM   2362  O OD1    . ASP A 1 151 ? -31.320 -29.014 -32.652 1.00 47.55  ? 151 ASP A OD1    1 
ATOM   2363  O OD2    . ASP A 1 151 ? -30.530 -30.482 -31.232 1.00 54.94  ? 151 ASP A OD2    1 
ATOM   2364  H H      . ASP A 1 151 ? -35.304 -29.908 -30.586 1.00 40.87  ? 151 ASP A H      1 
ATOM   2365  H HA     . ASP A 1 151 ? -33.388 -28.100 -31.156 1.00 44.04  ? 151 ASP A HA     1 
ATOM   2366  H HB2    . ASP A 1 151 ? -32.796 -30.210 -30.215 1.00 46.40  ? 151 ASP A HB2    1 
ATOM   2367  H HB3    . ASP A 1 151 ? -33.227 -30.886 -31.585 1.00 46.40  ? 151 ASP A HB3    1 
ATOM   2368  N N      . VAL A 1 152 ? -34.281 -27.576 -33.418 1.00 30.33  ? 152 VAL A N      1 
ATOM   2369  C CA     . VAL A 1 152 ? -34.456 -27.322 -34.845 1.00 29.92  ? 152 VAL A CA     1 
ATOM   2370  C C      . VAL A 1 152 ? -33.579 -26.163 -35.303 1.00 31.97  ? 152 VAL A C      1 
ATOM   2371  O O      . VAL A 1 152 ? -33.229 -25.290 -34.508 1.00 25.88  ? 152 VAL A O      1 
ATOM   2372  C CB     . VAL A 1 152 ? -35.917 -27.009 -35.191 1.00 34.79  ? 152 VAL A CB     1 
ATOM   2373  C CG1    . VAL A 1 152 ? -36.799 -28.195 -34.828 1.00 40.66  ? 152 VAL A CG1    1 
ATOM   2374  C CG2    . VAL A 1 152 ? -36.385 -25.736 -34.477 1.00 32.23  ? 152 VAL A CG2    1 
ATOM   2375  H H      . VAL A 1 152 ? -34.297 -26.866 -32.933 1.00 36.40  ? 152 VAL A H      1 
ATOM   2376  H HA     . VAL A 1 152 ? -34.192 -28.106 -35.351 1.00 35.90  ? 152 VAL A HA     1 
ATOM   2377  H HB     . VAL A 1 152 ? -35.991 -26.861 -36.147 1.00 41.75  ? 152 VAL A HB     1 
ATOM   2378  H HG11   . VAL A 1 152 ? -37.729 -27.937 -34.924 1.00 48.79  ? 152 VAL A HG11   1 
ATOM   2379  H HG12   . VAL A 1 152 ? -36.598 -28.931 -35.426 1.00 48.79  ? 152 VAL A HG12   1 
ATOM   2380  H HG13   . VAL A 1 152 ? -36.622 -28.456 -33.913 1.00 48.79  ? 152 VAL A HG13   1 
ATOM   2381  H HG21   . VAL A 1 152 ? -37.346 -25.654 -34.579 1.00 38.68  ? 152 VAL A HG21   1 
ATOM   2382  H HG22   . VAL A 1 152 ? -36.158 -25.798 -33.536 1.00 38.68  ? 152 VAL A HG22   1 
ATOM   2383  H HG23   . VAL A 1 152 ? -35.945 -24.968 -34.873 1.00 38.68  ? 152 VAL A HG23   1 
ATOM   2384  N N      . LYS A 1 153 ? -33.246 -26.169 -36.591 1.00 26.23  ? 153 LYS A N      1 
ATOM   2385  C CA     . LYS A 1 153 ? -32.418 -25.131 -37.201 1.00 27.16  ? 153 LYS A CA     1 
ATOM   2386  C C      . LYS A 1 153 ? -33.117 -23.780 -37.271 1.00 28.57  ? 153 LYS A C      1 
ATOM   2387  O O      . LYS A 1 153 ? -34.339 -23.701 -37.432 1.00 26.11  ? 153 LYS A O      1 
ATOM   2388  C CB     . LYS A 1 153 ? -32.007 -25.543 -38.618 1.00 26.99  ? 153 LYS A CB     1 
ATOM   2389  C CG     . LYS A 1 153 ? -30.953 -26.625 -38.694 1.00 35.66  ? 153 LYS A CG     1 
ATOM   2390  C CD     . LYS A 1 153 ? -30.583 -26.917 -40.153 1.00 36.55  ? 153 LYS A CD     1 
ATOM   2391  C CE     . LYS A 1 153 ? -29.362 -27.830 -40.258 1.00 40.17  ? 153 LYS A CE     1 
ATOM   2392  N NZ     . LYS A 1 153 ? -28.884 -27.999 -41.671 1.00 34.26  ? 153 LYS A NZ     1 
ATOM   2393  H H      . LYS A 1 153 ? -33.493 -26.778 -37.145 1.00 31.48  ? 153 LYS A H      1 
ATOM   2394  H HA     . LYS A 1 153 ? -31.611 -25.023 -36.674 1.00 32.60  ? 153 LYS A HA     1 
ATOM   2395  H HB2    . LYS A 1 153 ? -32.793 -25.867 -39.085 1.00 32.39  ? 153 LYS A HB2    1 
ATOM   2396  H HB3    . LYS A 1 153 ? -31.656 -24.764 -39.075 1.00 32.39  ? 153 LYS A HB3    1 
ATOM   2397  H HG2    . LYS A 1 153 ? -30.156 -26.332 -38.227 1.00 42.79  ? 153 LYS A HG2    1 
ATOM   2398  H HG3    . LYS A 1 153 ? -31.298 -27.440 -38.296 1.00 42.79  ? 153 LYS A HG3    1 
ATOM   2399  H HD2    . LYS A 1 153 ? -31.329 -27.357 -40.589 1.00 43.86  ? 153 LYS A HD2    1 
ATOM   2400  H HD3    . LYS A 1 153 ? -30.377 -26.083 -40.603 1.00 43.86  ? 153 LYS A HD3    1 
ATOM   2401  H HE2    . LYS A 1 153 ? -28.637 -27.449 -39.739 1.00 48.21  ? 153 LYS A HE2    1 
ATOM   2402  H HE3    . LYS A 1 153 ? -29.593 -28.707 -39.913 1.00 48.21  ? 153 LYS A HE3    1 
ATOM   2403  H HZ1    . LYS A 1 153 ? -29.529 -28.355 -42.170 1.00 41.11  ? 153 LYS A HZ1    1 
ATOM   2404  H HZ2    . LYS A 1 153 ? -28.658 -27.209 -42.012 1.00 41.11  ? 153 LYS A HZ2    1 
ATOM   2405  H HZ3    . LYS A 1 153 ? -28.174 -28.536 -41.690 1.00 41.11  ? 153 LYS A HZ3    1 
ATOM   2406  N N      . PHE A 1 154 ? -32.316 -22.722 -37.169 1.00 25.86  ? 154 PHE A N      1 
ATOM   2407  C CA     . PHE A 1 154 ? -32.771 -21.349 -37.369 1.00 21.88  ? 154 PHE A CA     1 
ATOM   2408  C C      . PHE A 1 154 ? -34.060 -21.051 -36.612 1.00 28.92  ? 154 PHE A C      1 
ATOM   2409  O O      . PHE A 1 154 ? -35.037 -20.527 -37.148 1.00 23.05  ? 154 PHE A O      1 
ATOM   2410  C CB     . PHE A 1 154 ? -32.896 -21.083 -38.869 1.00 24.29  ? 154 PHE A CB     1 
ATOM   2411  C CG     . PHE A 1 154 ? -31.589 -21.243 -39.579 1.00 22.36  ? 154 PHE A CG     1 
ATOM   2412  C CD1    . PHE A 1 154 ? -30.586 -20.298 -39.414 1.00 24.02  ? 154 PHE A CD1    1 
ATOM   2413  C CD2    . PHE A 1 154 ? -31.326 -22.363 -40.340 1.00 24.27  ? 154 PHE A CD2    1 
ATOM   2414  C CE1    . PHE A 1 154 ? -29.365 -20.455 -40.031 1.00 24.38  ? 154 PHE A CE1    1 
ATOM   2415  C CE2    . PHE A 1 154 ? -30.105 -22.528 -40.963 1.00 25.67  ? 154 PHE A CE2    1 
ATOM   2416  C CZ     . PHE A 1 154 ? -29.119 -21.575 -40.802 1.00 26.18  ? 154 PHE A CZ     1 
ATOM   2417  H H      . PHE A 1 154 ? -31.479 -22.777 -36.979 1.00 31.03  ? 154 PHE A H      1 
ATOM   2418  H HA     . PHE A 1 154 ? -32.090 -20.751 -37.025 1.00 26.26  ? 154 PHE A HA     1 
ATOM   2419  H HB2    . PHE A 1 154 ? -33.527 -21.712 -39.252 1.00 29.14  ? 154 PHE A HB2    1 
ATOM   2420  H HB3    . PHE A 1 154 ? -33.205 -20.174 -39.007 1.00 29.14  ? 154 PHE A HB3    1 
ATOM   2421  H HD1    . PHE A 1 154 ? -30.744 -19.545 -38.891 1.00 28.82  ? 154 PHE A HD1    1 
ATOM   2422  H HD2    . PHE A 1 154 ? -31.986 -23.010 -40.446 1.00 29.13  ? 154 PHE A HD2    1 
ATOM   2423  H HE1    . PHE A 1 154 ? -28.704 -19.809 -39.925 1.00 29.26  ? 154 PHE A HE1    1 
ATOM   2424  H HE2    . PHE A 1 154 ? -29.945 -23.281 -41.484 1.00 30.80  ? 154 PHE A HE2    1 
ATOM   2425  H HZ     . PHE A 1 154 ? -28.298 -21.678 -41.226 1.00 31.41  ? 154 PHE A HZ     1 
ATOM   2426  N N      . LYS A 1 155 ? -34.008 -21.370 -35.324 1.00 25.77  ? 155 LYS A N      1 
ATOM   2427  C CA     . LYS A 1 155 ? -35.107 -21.151 -34.400 1.00 27.78  ? 155 LYS A CA     1 
ATOM   2428  C C      . LYS A 1 155 ? -35.485 -19.678 -34.273 1.00 29.18  ? 155 LYS A C      1 
ATOM   2429  O O      . LYS A 1 155 ? -36.557 -19.350 -33.780 1.00 33.12  ? 155 LYS A O      1 
ATOM   2430  C CB     . LYS A 1 155 ? -34.718 -21.708 -33.031 1.00 30.16  ? 155 LYS A CB     1 
ATOM   2431  C CG     . LYS A 1 155 ? -35.792 -22.468 -32.317 1.00 31.97  ? 155 LYS A CG     1 
ATOM   2432  C CD     . LYS A 1 155 ? -35.214 -23.130 -31.071 1.00 28.95  ? 155 LYS A CD     1 
ATOM   2433  C CE     . LYS A 1 155 ? -36.289 -23.715 -30.187 1.00 32.90  ? 155 LYS A CE     1 
ATOM   2434  N NZ     . LYS A 1 155 ? -35.692 -24.454 -29.043 1.00 27.50  ? 155 LYS A NZ     1 
ATOM   2435  H H      . LYS A 1 155 ? -33.318 -21.726 -34.954 1.00 30.93  ? 155 LYS A H      1 
ATOM   2436  H HA     . LYS A 1 155 ? -35.886 -21.636 -34.713 1.00 33.33  ? 155 LYS A HA     1 
ATOM   2437  H HB2    . LYS A 1 155 ? -33.969 -22.312 -33.140 1.00 36.19  ? 155 LYS A HB2    1 
ATOM   2438  H HB3    . LYS A 1 155 ? -34.457 -20.967 -32.461 1.00 36.19  ? 155 LYS A HB3    1 
ATOM   2439  H HG2    . LYS A 1 155 ? -36.496 -21.860 -32.051 1.00 38.36  ? 155 LYS A HG2    1 
ATOM   2440  H HG3    . LYS A 1 155 ? -36.142 -23.160 -32.900 1.00 38.36  ? 155 LYS A HG3    1 
ATOM   2441  H HD2    . LYS A 1 155 ? -34.620 -23.848 -31.339 1.00 34.74  ? 155 LYS A HD2    1 
ATOM   2442  H HD3    . LYS A 1 155 ? -34.727 -22.468 -30.556 1.00 34.74  ? 155 LYS A HD3    1 
ATOM   2443  H HE2    . LYS A 1 155 ? -36.839 -22.998 -29.833 1.00 39.48  ? 155 LYS A HE2    1 
ATOM   2444  H HE3    . LYS A 1 155 ? -36.830 -24.333 -30.703 1.00 39.48  ? 155 LYS A HE3    1 
ATOM   2445  H HZ1    . LYS A 1 155 ? -36.336 -24.796 -28.532 1.00 33.00  ? 155 LYS A HZ1    1 
ATOM   2446  H HZ2    . LYS A 1 155 ? -35.179 -25.116 -29.344 1.00 33.00  ? 155 LYS A HZ2    1 
ATOM   2447  H HZ3    . LYS A 1 155 ? -35.195 -23.903 -28.552 1.00 33.00  ? 155 LYS A HZ3    1 
ATOM   2448  N N      . GLY A 1 156 ? -34.600 -18.789 -34.715 1.00 25.18  ? 156 GLY A N      1 
ATOM   2449  C CA     . GLY A 1 156 ? -34.827 -17.366 -34.579 1.00 23.19  ? 156 GLY A CA     1 
ATOM   2450  C C      . GLY A 1 156 ? -35.673 -16.746 -35.676 1.00 23.82  ? 156 GLY A C      1 
ATOM   2451  O O      . GLY A 1 156 ? -36.047 -15.577 -35.583 1.00 24.64  ? 156 GLY A O      1 
ATOM   2452  H H      . GLY A 1 156 ? -33.856 -18.989 -35.097 1.00 30.21  ? 156 GLY A H      1 
ATOM   2453  H HA2    . GLY A 1 156 ? -35.262 -17.192 -33.730 1.00 27.83  ? 156 GLY A HA2    1 
ATOM   2454  H HA3    . GLY A 1 156 ? -33.970 -16.912 -34.573 1.00 27.83  ? 156 GLY A HA3    1 
ATOM   2455  N N      . ASN A 1 157 ? -35.989 -17.529 -36.702 1.00 23.64  ? 157 ASN A N      1 
ATOM   2456  C CA     . ASN A 1 157 ? -36.709 -17.018 -37.868 1.00 23.14  ? 157 ASN A CA     1 
ATOM   2457  C C      . ASN A 1 157 ? -38.044 -16.377 -37.524 1.00 27.85  ? 157 ASN A C      1 
ATOM   2458  O O      . ASN A 1 157 ? -38.754 -16.819 -36.616 1.00 26.77  ? 157 ASN A O      1 
ATOM   2459  C CB     . ASN A 1 157 ? -36.960 -18.136 -38.882 1.00 23.27  ? 157 ASN A CB     1 
ATOM   2460  C CG     . ASN A 1 157 ? -35.726 -18.500 -39.682 1.00 28.48  ? 157 ASN A CG     1 
ATOM   2461  O OD1    . ASN A 1 157 ? -34.690 -17.850 -39.586 1.00 24.78  ? 157 ASN A OD1    1 
ATOM   2462  N ND2    . ASN A 1 157 ? -35.842 -19.538 -40.494 1.00 25.62  ? 157 ASN A ND2    1 
ATOM   2463  H H      . ASN A 1 157 ? -35.798 -18.366 -36.751 1.00 28.36  ? 157 ASN A H      1 
ATOM   2464  H HA     . ASN A 1 157 ? -36.165 -16.340 -38.297 1.00 27.77  ? 157 ASN A HA     1 
ATOM   2465  H HB2    . ASN A 1 157 ? -37.245 -18.931 -38.411 1.00 27.93  ? 157 ASN A HB2    1 
ATOM   2466  H HB3    . ASN A 1 157 ? -37.649 -17.852 -39.503 1.00 27.93  ? 157 ASN A HB3    1 
ATOM   2467  H HD21   . ASN A 1 157 ? -35.172 -19.787 -40.971 1.00 30.74  ? 157 ASN A HD21   1 
ATOM   2468  H HD22   . ASN A 1 157 ? -36.588 -19.963 -40.544 1.00 30.74  ? 157 ASN A HD22   1 
ATOM   2469  N N      . ILE A 1 158 ? -38.363 -15.323 -38.265 1.00 24.12  ? 158 ILE A N      1 
ATOM   2470  C CA     . ILE A 1 158 ? -39.679 -14.710 -38.246 1.00 27.19  ? 158 ILE A CA     1 
ATOM   2471  C C      . ILE A 1 158 ? -40.680 -15.609 -38.977 1.00 30.95  ? 158 ILE A C      1 
ATOM   2472  O O      . ILE A 1 158 ? -40.359 -16.195 -40.013 1.00 29.08  ? 158 ILE A O      1 
ATOM   2473  C CB     . ILE A 1 158 ? -39.646 -13.306 -38.896 1.00 29.61  ? 158 ILE A CB     1 
ATOM   2474  C CG1    . ILE A 1 158 ? -38.903 -12.336 -37.971 1.00 29.33  ? 158 ILE A CG1    1 
ATOM   2475  C CG2    . ILE A 1 158 ? -41.065 -12.796 -39.195 1.00 32.95  ? 158 ILE A CG2    1 
ATOM   2476  C CD1    . ILE A 1 158 ? -38.723 -10.924 -38.520 1.00 31.73  ? 158 ILE A CD1    1 
ATOM   2477  H H      . ILE A 1 158 ? -37.815 -14.935 -38.802 1.00 28.94  ? 158 ILE A H      1 
ATOM   2478  H HA     . ILE A 1 158 ? -39.973 -14.612 -37.327 1.00 32.62  ? 158 ILE A HA     1 
ATOM   2479  H HB     . ILE A 1 158 ? -39.159 -13.366 -39.733 1.00 35.53  ? 158 ILE A HB     1 
ATOM   2480  H HG12   . ILE A 1 158 ? -39.397 -12.265 -37.139 1.00 35.19  ? 158 ILE A HG12   1 
ATOM   2481  H HG13   . ILE A 1 158 ? -38.019 -12.695 -37.794 1.00 35.19  ? 158 ILE A HG13   1 
ATOM   2482  H HG21   . ILE A 1 158 ? -41.027 -11.854 -39.417 1.00 39.55  ? 158 ILE A HG21   1 
ATOM   2483  H HG22   . ILE A 1 158 ? -41.431 -13.289 -39.946 1.00 39.55  ? 158 ILE A HG22   1 
ATOM   2484  H HG23   . ILE A 1 158 ? -41.619 -12.927 -38.410 1.00 39.55  ? 158 ILE A HG23   1 
ATOM   2485  H HD11   . ILE A 1 158 ? -38.058 -10.461 -37.987 1.00 38.07  ? 158 ILE A HD11   1 
ATOM   2486  H HD12   . ILE A 1 158 ? -38.427 -10.980 -39.442 1.00 38.07  ? 158 ILE A HD12   1 
ATOM   2487  H HD13   . ILE A 1 158 ? -39.570 -10.454 -38.473 1.00 38.07  ? 158 ILE A HD13   1 
ATOM   2488  N N      . ASP A 1 159 ? -41.884 -15.718 -38.419 1.00 32.61  ? 159 ASP A N      1 
ATOM   2489  C CA     . ASP A 1 159 ? -42.980 -16.438 -39.067 1.00 33.93  ? 159 ASP A CA     1 
ATOM   2490  C C      . ASP A 1 159 ? -43.655 -15.496 -40.050 1.00 27.96  ? 159 ASP A C      1 
ATOM   2491  O O      . ASP A 1 159 ? -44.323 -14.540 -39.653 1.00 33.38  ? 159 ASP A O      1 
ATOM   2492  C CB     . ASP A 1 159 ? -43.983 -16.952 -38.028 1.00 35.96  ? 159 ASP A CB     1 
ATOM   2493  C CG     . ASP A 1 159 ? -45.066 -17.847 -38.633 1.00 44.50  ? 159 ASP A CG     1 
ATOM   2494  O OD1    . ASP A 1 159 ? -45.321 -17.771 -39.857 1.00 40.48  ? 159 ASP A OD1    1 
ATOM   2495  O OD2    . ASP A 1 159 ? -45.669 -18.630 -37.867 1.00 42.09  ? 159 ASP A OD2    1 
ATOM   2496  H H      . ASP A 1 159 ? -42.094 -15.380 -37.657 1.00 39.14  ? 159 ASP A H      1 
ATOM   2497  H HA     . ASP A 1 159 ? -42.629 -17.198 -39.557 1.00 40.71  ? 159 ASP A HA     1 
ATOM   2498  H HB2    . ASP A 1 159 ? -43.506 -17.469 -37.363 1.00 43.15  ? 159 ASP A HB2    1 
ATOM   2499  H HB3    . ASP A 1 159 ? -44.418 -16.194 -37.608 1.00 43.15  ? 159 ASP A HB3    1 
ATOM   2500  N N      . ILE A 1 160 ? -43.468 -15.760 -41.335 1.00 31.16  ? 160 ILE A N      1 
ATOM   2501  C CA     . ILE A 1 160 ? -43.960 -14.854 -42.364 1.00 37.01  ? 160 ILE A CA     1 
ATOM   2502  C C      . ILE A 1 160 ? -45.474 -14.685 -42.277 1.00 36.66  ? 160 ILE A C      1 
ATOM   2503  O O      . ILE A 1 160 ? -45.995 -13.607 -42.549 1.00 35.90  ? 160 ILE A O      1 
ATOM   2504  C CB     . ILE A 1 160 ? -43.578 -15.344 -43.773 1.00 36.24  ? 160 ILE A CB     1 
ATOM   2505  C CG1    . ILE A 1 160 ? -42.058 -15.476 -43.893 1.00 43.46  ? 160 ILE A CG1    1 
ATOM   2506  C CG2    . ILE A 1 160 ? -44.107 -14.386 -44.847 1.00 41.62  ? 160 ILE A CG2    1 
ATOM   2507  C CD1    . ILE A 1 160 ? -41.293 -14.159 -43.698 1.00 44.59  ? 160 ILE A CD1    1 
ATOM   2508  H H      . ILE A 1 160 ? -43.063 -16.455 -41.637 1.00 37.40  ? 160 ILE A H      1 
ATOM   2509  H HA     . ILE A 1 160 ? -43.561 -13.981 -42.230 1.00 44.41  ? 160 ILE A HA     1 
ATOM   2510  H HB     . ILE A 1 160 ? -43.976 -16.217 -43.915 1.00 43.49  ? 160 ILE A HB     1 
ATOM   2511  H HG12   . ILE A 1 160 ? -41.741 -16.102 -43.224 1.00 52.15  ? 160 ILE A HG12   1 
ATOM   2512  H HG13   . ILE A 1 160 ? -41.845 -15.810 -44.778 1.00 52.15  ? 160 ILE A HG13   1 
ATOM   2513  H HG21   . ILE A 1 160 ? -43.648 -14.566 -45.682 1.00 49.94  ? 160 ILE A HG21   1 
ATOM   2514  H HG22   . ILE A 1 160 ? -45.060 -14.527 -44.958 1.00 49.94  ? 160 ILE A HG22   1 
ATOM   2515  H HG23   . ILE A 1 160 ? -43.936 -13.473 -44.567 1.00 49.94  ? 160 ILE A HG23   1 
ATOM   2516  H HD11   . ILE A 1 160 ? -40.351 -14.317 -43.868 1.00 53.50  ? 160 ILE A HD11   1 
ATOM   2517  H HD12   . ILE A 1 160 ? -41.632 -13.496 -44.319 1.00 53.50  ? 160 ILE A HD12   1 
ATOM   2518  H HD13   . ILE A 1 160 ? -41.415 -13.852 -42.786 1.00 53.50  ? 160 ILE A HD13   1 
ATOM   2519  N N      . LYS A 1 161 ? -46.174 -15.742 -41.875 1.00 36.99  ? 161 LYS A N      1 
ATOM   2520  C CA     . LYS A 1 161 ? -47.629 -15.696 -41.782 1.00 36.46  ? 161 LYS A CA     1 
ATOM   2521  C C      . LYS A 1 161 ? -48.059 -14.720 -40.698 1.00 38.80  ? 161 LYS A C      1 
ATOM   2522  O O      . LYS A 1 161 ? -49.018 -13.963 -40.874 1.00 40.65  ? 161 LYS A O      1 
ATOM   2523  C CB     . LYS A 1 161 ? -48.192 -17.088 -41.504 1.00 41.22  ? 161 LYS A CB     1 
ATOM   2524  C CG     . LYS A 1 161 ? -47.941 -18.074 -42.626 1.00 43.72  ? 161 LYS A CG     1 
ATOM   2525  C CD     . LYS A 1 161 ? -48.231 -19.496 -42.183 1.00 60.98  ? 161 LYS A CD     1 
ATOM   2526  C CE     . LYS A 1 161 ? -47.547 -20.512 -43.082 1.00 74.55  ? 161 LYS A CE     1 
ATOM   2527  N NZ     . LYS A 1 161 ? -47.471 -21.849 -42.425 1.00 91.59  ? 161 LYS A NZ     1 
ATOM   2528  H H      . LYS A 1 161 ? -45.830 -16.498 -41.651 1.00 44.39  ? 161 LYS A H      1 
ATOM   2529  H HA     . LYS A 1 161 ? -47.992 -15.387 -42.627 1.00 43.75  ? 161 LYS A HA     1 
ATOM   2530  H HB2    . LYS A 1 161 ? -47.778 -17.438 -40.700 1.00 49.47  ? 161 LYS A HB2    1 
ATOM   2531  H HB3    . LYS A 1 161 ? -49.151 -17.019 -41.378 1.00 49.47  ? 161 LYS A HB3    1 
ATOM   2532  H HG2    . LYS A 1 161 ? -48.522 -17.864 -43.374 1.00 52.47  ? 161 LYS A HG2    1 
ATOM   2533  H HG3    . LYS A 1 161 ? -47.011 -18.021 -42.897 1.00 52.47  ? 161 LYS A HG3    1 
ATOM   2534  H HD2    . LYS A 1 161 ? -47.904 -19.624 -41.279 1.00 73.17  ? 161 LYS A HD2    1 
ATOM   2535  H HD3    . LYS A 1 161 ? -49.187 -19.653 -42.220 1.00 73.17  ? 161 LYS A HD3    1 
ATOM   2536  H HE2    . LYS A 1 161 ? -48.053 -20.605 -43.904 1.00 89.47  ? 161 LYS A HE2    1 
ATOM   2537  H HE3    . LYS A 1 161 ? -46.643 -20.217 -43.274 1.00 89.47  ? 161 LYS A HE3    1 
ATOM   2538  H HZ1    . LYS A 1 161 ? -47.068 -22.431 -42.965 1.00 109.91 ? 161 LYS A HZ1    1 
ATOM   2539  H HZ2    . LYS A 1 161 ? -47.008 -21.789 -41.667 1.00 109.91 ? 161 LYS A HZ2    1 
ATOM   2540  H HZ3    . LYS A 1 161 ? -48.290 -22.144 -42.241 1.00 109.91 ? 161 LYS A HZ3    1 
ATOM   2541  N N      . LYS A 1 162 ? -47.337 -14.724 -39.582 1.00 36.61  ? 162 LYS A N      1 
ATOM   2542  C CA     . LYS A 1 162 ? -47.617 -13.785 -38.504 1.00 35.21  ? 162 LYS A CA     1 
ATOM   2543  C C      . LYS A 1 162 ? -47.412 -12.357 -38.988 1.00 33.90  ? 162 LYS A C      1 
ATOM   2544  O O      . LYS A 1 162 ? -48.181 -11.470 -38.641 1.00 37.52  ? 162 LYS A O      1 
ATOM   2545  C CB     . LYS A 1 162 ? -46.737 -14.065 -37.282 1.00 37.07  ? 162 LYS A CB     1 
ATOM   2546  C CG     . LYS A 1 162 ? -46.980 -15.429 -36.639 1.00 35.97  ? 162 LYS A CG     1 
ATOM   2547  C CD     . LYS A 1 162 ? -46.291 -15.541 -35.291 1.00 35.60  ? 162 LYS A CD     1 
ATOM   2548  C CE     . LYS A 1 162 ? -46.445 -16.932 -34.703 1.00 34.67  ? 162 LYS A CE     1 
ATOM   2549  N NZ     . LYS A 1 162 ? -46.016 -16.967 -33.287 1.00 47.93  ? 162 LYS A NZ     1 
ATOM   2550  H H      . LYS A 1 162 ? -46.682 -15.259 -39.425 1.00 43.93  ? 162 LYS A H      1 
ATOM   2551  H HA     . LYS A 1 162 ? -48.544 -13.881 -38.234 1.00 42.25  ? 162 LYS A HA     1 
ATOM   2552  H HB2    . LYS A 1 162 ? -45.806 -14.027 -37.552 1.00 44.49  ? 162 LYS A HB2    1 
ATOM   2553  H HB3    . LYS A 1 162 ? -46.911 -13.387 -36.611 1.00 44.49  ? 162 LYS A HB3    1 
ATOM   2554  H HG2    . LYS A 1 162 ? -47.933 -15.552 -36.503 1.00 43.17  ? 162 LYS A HG2    1 
ATOM   2555  H HG3    . LYS A 1 162 ? -46.634 -16.124 -37.219 1.00 43.17  ? 162 LYS A HG3    1 
ATOM   2556  H HD2    . LYS A 1 162 ? -45.344 -15.360 -35.399 1.00 42.72  ? 162 LYS A HD2    1 
ATOM   2557  H HD3    . LYS A 1 162 ? -46.687 -14.905 -34.675 1.00 42.72  ? 162 LYS A HD3    1 
ATOM   2558  H HE2    . LYS A 1 162 ? -47.377 -17.197 -34.746 1.00 41.60  ? 162 LYS A HE2    1 
ATOM   2559  H HE3    . LYS A 1 162 ? -45.895 -17.555 -35.204 1.00 41.60  ? 162 LYS A HE3    1 
ATOM   2560  H HZ1    . LYS A 1 162 ? -45.158 -16.739 -33.224 1.00 57.51  ? 162 LYS A HZ1    1 
ATOM   2561  H HZ2    . LYS A 1 162 ? -46.503 -16.397 -32.808 1.00 57.51  ? 162 LYS A HZ2    1 
ATOM   2562  H HZ3    . LYS A 1 162 ? -46.122 -17.786 -32.957 1.00 57.51  ? 162 LYS A HZ3    1 
ATOM   2563  N N      . LEU A 1 163 ? -46.380 -12.139 -39.798 1.00 35.75  ? 163 LEU A N      1 
ATOM   2564  C CA     . LEU A 1 163 ? -46.123 -10.810 -40.340 1.00 38.61  ? 163 LEU A CA     1 
ATOM   2565  C C      . LEU A 1 163 ? -47.213 -10.417 -41.339 1.00 38.89  ? 163 LEU A C      1 
ATOM   2566  O O      . LEU A 1 163 ? -47.686 -9.284  -41.333 1.00 36.41  ? 163 LEU A O      1 
ATOM   2567  C CB     . LEU A 1 163 ? -44.746 -10.746 -41.011 1.00 36.71  ? 163 LEU A CB     1 
ATOM   2568  C CG     . LEU A 1 163 ? -44.391 -9.384  -41.631 1.00 38.60  ? 163 LEU A CG     1 
ATOM   2569  C CD1    . LEU A 1 163 ? -44.595 -8.252  -40.641 1.00 36.17  ? 163 LEU A CD1    1 
ATOM   2570  C CD2    . LEU A 1 163 ? -42.956 -9.364  -42.142 1.00 38.22  ? 163 LEU A CD2    1 
ATOM   2571  H H      . LEU A 1 163 ? -45.817 -12.740 -40.047 1.00 42.90  ? 163 LEU A H      1 
ATOM   2572  H HA     . LEU A 1 163 ? -46.137 -10.170 -39.612 1.00 46.33  ? 163 LEU A HA     1 
ATOM   2573  H HB2    . LEU A 1 163 ? -44.069 -10.951 -40.347 1.00 44.05  ? 163 LEU A HB2    1 
ATOM   2574  H HB3    . LEU A 1 163 ? -44.717 -11.407 -41.720 1.00 44.05  ? 163 LEU A HB3    1 
ATOM   2575  H HG     . LEU A 1 163 ? -44.975 -9.223  -42.389 1.00 46.32  ? 163 LEU A HG     1 
ATOM   2576  H HD11   . LEU A 1 163 ? -44.232 -7.437  -41.020 1.00 43.41  ? 163 LEU A HD11   1 
ATOM   2577  H HD12   . LEU A 1 163 ? -45.543 -8.142  -40.472 1.00 43.41  ? 163 LEU A HD12   1 
ATOM   2578  H HD13   . LEU A 1 163 ? -44.133 -8.467  -39.816 1.00 43.41  ? 163 LEU A HD13   1 
ATOM   2579  H HD21   . LEU A 1 163 ? -42.819 -8.559  -42.666 1.00 45.87  ? 163 LEU A HD21   1 
ATOM   2580  H HD22   . LEU A 1 163 ? -42.351 -9.372  -41.384 1.00 45.87  ? 163 LEU A HD22   1 
ATOM   2581  H HD23   . LEU A 1 163 ? -42.805 -10.147 -42.694 1.00 45.87  ? 163 LEU A HD23   1 
ATOM   2582  N N      . GLU A 1 164 ? -47.601 -11.353 -42.200 1.00 40.04  ? 164 GLU A N      1 
ATOM   2583  C CA     . GLU A 1 164 ? -48.684 -11.110 -43.150 1.00 40.10  ? 164 GLU A CA     1 
ATOM   2584  C C      . GLU A 1 164 ? -49.963 -10.738 -42.410 1.00 38.26  ? 164 GLU A C      1 
ATOM   2585  O O      . GLU A 1 164 ? -50.671 -9.810  -42.801 1.00 43.93  ? 164 GLU A O      1 
ATOM   2586  C CB     . GLU A 1 164 ? -48.913 -12.340 -44.033 1.00 39.84  ? 164 GLU A CB     1 
ATOM   2587  C CG     . GLU A 1 164 ? -47.923 -12.461 -45.190 1.00 43.68  ? 164 GLU A CG     1 
ATOM   2588  C CD     . GLU A 1 164 ? -47.952 -13.824 -45.870 1.00 67.76  ? 164 GLU A CD     1 
ATOM   2589  O OE1    . GLU A 1 164 ? -48.540 -14.772 -45.304 1.00 65.54  ? 164 GLU A OE1    1 
ATOM   2590  O OE2    . GLU A 1 164 ? -47.378 -13.946 -46.975 1.00 63.66  ? 164 GLU A OE2    1 
ATOM   2591  H H      . GLU A 1 164 ? -47.254 -12.138 -42.255 1.00 48.05  ? 164 GLU A H      1 
ATOM   2592  H HA     . GLU A 1 164 ? -48.441 -10.367 -43.725 1.00 48.12  ? 164 GLU A HA     1 
ATOM   2593  H HB2    . GLU A 1 164 ? -48.829 -13.133 -43.481 1.00 47.81  ? 164 GLU A HB2    1 
ATOM   2594  H HB3    . GLU A 1 164 ? -49.806 -12.294 -44.409 1.00 47.81  ? 164 GLU A HB3    1 
ATOM   2595  H HG2    . GLU A 1 164 ? -48.136 -11.790 -45.857 1.00 52.41  ? 164 GLU A HG2    1 
ATOM   2596  H HG3    . GLU A 1 164 ? -47.026 -12.317 -44.851 1.00 52.41  ? 164 GLU A HG3    1 
ATOM   2597  N N      . LYS A 1 165 ? -50.242 -11.457 -41.327 1.00 40.70  ? 165 LYS A N      1 
ATOM   2598  C CA     . LYS A 1 165 ? -51.434 -11.203 -40.526 1.00 43.03  ? 165 LYS A CA     1 
ATOM   2599  C C      . LYS A 1 165 ? -51.393 -9.814  -39.897 1.00 45.15  ? 165 LYS A C      1 
ATOM   2600  O O      . LYS A 1 165 ? -52.389 -9.088  -39.906 1.00 46.01  ? 165 LYS A O      1 
ATOM   2601  C CB     . LYS A 1 165 ? -51.581 -12.271 -39.439 1.00 42.50  ? 165 LYS A CB     1 
ATOM   2602  C CG     . LYS A 1 165 ? -52.801 -12.097 -38.550 1.00 53.21  ? 165 LYS A CG     1 
ATOM   2603  C CD     . LYS A 1 165 ? -52.953 -13.271 -37.594 1.00 60.16  ? 165 LYS A CD     1 
ATOM   2604  C CE     . LYS A 1 165 ? -54.210 -13.150 -36.748 1.00 68.94  ? 165 LYS A CE     1 
ATOM   2605  N NZ     . LYS A 1 165 ? -54.427 -14.354 -35.900 1.00 80.73  ? 165 LYS A NZ     1 
ATOM   2606  H H      . LYS A 1 165 ? -49.754 -12.101 -41.034 1.00 48.84  ? 165 LYS A H      1 
ATOM   2607  H HA     . LYS A 1 165 ? -52.215 -11.249 -41.099 1.00 51.63  ? 165 LYS A HA     1 
ATOM   2608  H HB2    . LYS A 1 165 ? -51.648 -13.140 -39.865 1.00 51.00  ? 165 LYS A HB2    1 
ATOM   2609  H HB3    . LYS A 1 165 ? -50.796 -12.245 -38.870 1.00 51.00  ? 165 LYS A HB3    1 
ATOM   2610  H HG2    . LYS A 1 165 ? -52.705 -11.288 -38.024 1.00 63.85  ? 165 LYS A HG2    1 
ATOM   2611  H HG3    . LYS A 1 165 ? -53.597 -12.048 -39.102 1.00 63.85  ? 165 LYS A HG3    1 
ATOM   2612  H HD2    . LYS A 1 165 ? -53.010 -14.094 -38.105 1.00 72.19  ? 165 LYS A HD2    1 
ATOM   2613  H HD3    . LYS A 1 165 ? -52.188 -13.299 -36.998 1.00 72.19  ? 165 LYS A HD3    1 
ATOM   2614  H HE2    . LYS A 1 165 ? -54.130 -12.379 -36.165 1.00 82.73  ? 165 LYS A HE2    1 
ATOM   2615  H HE3    . LYS A 1 165 ? -54.978 -13.051 -37.332 1.00 82.73  ? 165 LYS A HE3    1 
ATOM   2616  H HZ1    . LYS A 1 165 ? -55.168 -14.256 -35.417 1.00 96.87  ? 165 LYS A HZ1    1 
ATOM   2617  H HZ2    . LYS A 1 165 ? -54.510 -15.076 -36.413 1.00 96.87  ? 165 LYS A HZ2    1 
ATOM   2618  H HZ3    . LYS A 1 165 ? -53.736 -14.467 -35.351 1.00 96.87  ? 165 LYS A HZ3    1 
ATOM   2619  N N      . LEU A 1 166 ? -50.236 -9.444  -39.356 1.00 42.02  ? 166 LEU A N      1 
ATOM   2620  C CA     . LEU A 1 166 ? -50.078 -8.141  -38.722 1.00 40.31  ? 166 LEU A CA     1 
ATOM   2621  C C      . LEU A 1 166 ? -50.324 -7.015  -39.717 1.00 38.88  ? 166 LEU A C      1 
ATOM   2622  O O      . LEU A 1 166 ? -50.998 -6.036  -39.399 1.00 45.57  ? 166 LEU A O      1 
ATOM   2623  C CB     . LEU A 1 166 ? -48.681 -7.998  -38.115 1.00 40.31  ? 166 LEU A CB     1 
ATOM   2624  C CG     . LEU A 1 166 ? -48.414 -6.664  -37.411 1.00 40.08  ? 166 LEU A CG     1 
ATOM   2625  C CD1    . LEU A 1 166 ? -49.127 -6.617  -36.074 1.00 41.57  ? 166 LEU A CD1    1 
ATOM   2626  C CD2    . LEU A 1 166 ? -46.928 -6.441  -37.240 1.00 46.48  ? 166 LEU A CD2    1 
ATOM   2627  H H      . LEU A 1 166 ? -49.527 -9.930  -39.343 1.00 50.42  ? 166 LEU A H      1 
ATOM   2628  H HA     . LEU A 1 166 ? -50.727 -8.057  -38.006 1.00 48.38  ? 166 LEU A HA     1 
ATOM   2629  H HB2    . LEU A 1 166 ? -48.555 -8.704  -37.462 1.00 48.37  ? 166 LEU A HB2    1 
ATOM   2630  H HB3    . LEU A 1 166 ? -48.026 -8.090  -38.824 1.00 48.37  ? 166 LEU A HB3    1 
ATOM   2631  H HG     . LEU A 1 166 ? -48.756 -5.937  -37.953 1.00 48.09  ? 166 LEU A HG     1 
ATOM   2632  H HD11   . LEU A 1 166 ? -48.879 -5.801  -35.613 1.00 49.88  ? 166 LEU A HD11   1 
ATOM   2633  H HD12   . LEU A 1 166 ? -50.085 -6.633  -36.226 1.00 49.88  ? 166 LEU A HD12   1 
ATOM   2634  H HD13   . LEU A 1 166 ? -48.862 -7.388  -35.549 1.00 49.88  ? 166 LEU A HD13   1 
ATOM   2635  H HD21   . LEU A 1 166 ? -46.787 -5.607  -36.765 1.00 55.78  ? 166 LEU A HD21   1 
ATOM   2636  H HD22   . LEU A 1 166 ? -46.556 -7.179  -36.733 1.00 55.78  ? 166 LEU A HD22   1 
ATOM   2637  H HD23   . LEU A 1 166 ? -46.513 -6.398  -38.116 1.00 55.78  ? 166 LEU A HD23   1 
ATOM   2638  N N      . ILE A 1 167 ? -49.770 -7.149  -40.915 1.00 36.52  ? 167 ILE A N      1 
ATOM   2639  C CA     . ILE A 1 167 ? -49.924 -6.123  -41.937 1.00 41.47  ? 167 ILE A CA     1 
ATOM   2640  C C      . ILE A 1 167 ? -51.392 -5.968  -42.332 1.00 44.84  ? 167 ILE A C      1 
ATOM   2641  O O      . ILE A 1 167 ? -51.879 -4.852  -42.518 1.00 46.16  ? 167 ILE A O      1 
ATOM   2642  C CB     . ILE A 1 167 ? -49.082 -6.447  -43.186 1.00 39.33  ? 167 ILE A CB     1 
ATOM   2643  C CG1    . ILE A 1 167 ? -47.592 -6.417  -42.833 1.00 41.45  ? 167 ILE A CG1    1 
ATOM   2644  C CG2    . ILE A 1 167 ? -49.364 -5.443  -44.300 1.00 39.75  ? 167 ILE A CG2    1 
ATOM   2645  C CD1    . ILE A 1 167 ? -46.670 -6.921  -43.941 1.00 44.05  ? 167 ILE A CD1    1 
ATOM   2646  H H      . ILE A 1 167 ? -49.299 -7.825  -41.162 1.00 43.82  ? 167 ILE A H      1 
ATOM   2647  H HA     . ILE A 1 167 ? -49.618 -5.274  -41.581 1.00 49.77  ? 167 ILE A HA     1 
ATOM   2648  H HB     . ILE A 1 167 ? -49.313 -7.336  -43.498 1.00 47.20  ? 167 ILE A HB     1 
ATOM   2649  H HG12   . ILE A 1 167 ? -47.341 -5.500  -42.641 1.00 49.74  ? 167 ILE A HG12   1 
ATOM   2650  H HG13   . ILE A 1 167 ? -47.441 -6.964  -42.048 1.00 49.74  ? 167 ILE A HG13   1 
ATOM   2651  H HG21   . ILE A 1 167 ? -48.669 -5.508  -44.972 1.00 47.70  ? 167 ILE A HG21   1 
ATOM   2652  H HG22   . ILE A 1 167 ? -50.224 -5.644  -44.701 1.00 47.70  ? 167 ILE A HG22   1 
ATOM   2653  H HG23   . ILE A 1 167 ? -49.374 -4.549  -43.923 1.00 47.70  ? 167 ILE A HG23   1 
ATOM   2654  H HD11   . ILE A 1 167 ? -45.794 -7.101  -43.564 1.00 52.86  ? 167 ILE A HD11   1 
ATOM   2655  H HD12   . ILE A 1 167 ? -47.043 -7.735  -44.314 1.00 52.86  ? 167 ILE A HD12   1 
ATOM   2656  H HD13   . ILE A 1 167 ? -46.601 -6.242  -44.630 1.00 52.86  ? 167 ILE A HD13   1 
ATOM   2657  N N      . ALA A 1 168 ? -52.093 -7.091  -42.450 1.00 43.91  ? 168 ALA A N      1 
ATOM   2658  C CA     . ALA A 1 168 ? -53.492 -7.074  -42.855 1.00 42.84  ? 168 ALA A CA     1 
ATOM   2659  C C      . ALA A 1 168 ? -54.380 -6.437  -41.781 1.00 46.42  ? 168 ALA A C      1 
ATOM   2660  O O      . ALA A 1 168 ? -55.265 -5.638  -42.089 1.00 48.89  ? 168 ALA A O      1 
ATOM   2661  C CB     . ALA A 1 168 ? -53.962 -8.490  -43.166 1.00 42.82  ? 168 ALA A CB     1 
ATOM   2662  H H      . ALA A 1 168 ? -51.780 -7.878  -42.301 1.00 52.69  ? 168 ALA A H      1 
ATOM   2663  H HA     . ALA A 1 168 ? -53.578 -6.547  -43.664 1.00 51.41  ? 168 ALA A HA     1 
ATOM   2664  H HB1    . ALA A 1 168 ? -54.894 -8.461  -43.434 1.00 51.38  ? 168 ALA A HB1    1 
ATOM   2665  H HB2    . ALA A 1 168 ? -53.421 -8.851  -43.886 1.00 51.38  ? 168 ALA A HB2    1 
ATOM   2666  H HB3    . ALA A 1 168 ? -53.862 -9.037  -42.371 1.00 51.38  ? 168 ALA A HB3    1 
ATOM   2667  N N      . GLU A 1 169 ? -54.131 -6.775  -40.520 1.00 43.15  ? 169 GLU A N      1 
ATOM   2668  C CA     . GLU A 1 169 ? -54.983 -6.304  -39.431 1.00 44.87  ? 169 GLU A CA     1 
ATOM   2669  C C      . GLU A 1 169 ? -54.703 -4.858  -39.023 1.00 46.81  ? 169 GLU A C      1 
ATOM   2670  O O      . GLU A 1 169 ? -55.637 -4.100  -38.752 1.00 46.32  ? 169 GLU A O      1 
ATOM   2671  C CB     . GLU A 1 169 ? -54.827 -7.212  -38.213 1.00 50.07  ? 169 GLU A CB     1 
ATOM   2672  C CG     . GLU A 1 169 ? -55.320 -8.631  -38.439 1.00 63.94  ? 169 GLU A CG     1 
ATOM   2673  C CD     . GLU A 1 169 ? -55.245 -9.479  -37.185 1.00 80.74  ? 169 GLU A CD     1 
ATOM   2674  O OE1    . GLU A 1 169 ? -54.672 -9.008  -36.179 1.00 80.07  ? 169 GLU A OE1    1 
ATOM   2675  O OE2    . GLU A 1 169 ? -55.764 -10.614 -37.206 1.00 78.22  ? 169 GLU A OE2    1 
ATOM   2676  H H      . GLU A 1 169 ? -53.478 -7.274  -40.268 1.00 51.78  ? 169 GLU A H      1 
ATOM   2677  H HA     . GLU A 1 169 ? -55.909 -6.354  -39.717 1.00 53.84  ? 169 GLU A HA     1 
ATOM   2678  H HB2    . GLU A 1 169 ? -53.887 -7.258  -37.976 1.00 60.09  ? 169 GLU A HB2    1 
ATOM   2679  H HB3    . GLU A 1 169 ? -55.334 -6.836  -37.476 1.00 60.09  ? 169 GLU A HB3    1 
ATOM   2680  H HG2    . GLU A 1 169 ? -56.246 -8.601  -38.725 1.00 76.73  ? 169 GLU A HG2    1 
ATOM   2681  H HG3    . GLU A 1 169 ? -54.776 -9.053  -39.121 1.00 76.73  ? 169 GLU A HG3    1 
ATOM   2682  N N      . LYS A 1 170 ? -53.426 -4.480  -38.973 1.00 45.89  ? 170 LYS A N      1 
ATOM   2683  C CA     . LYS A 1 170 ? -53.033 -3.154  -38.492 1.00 42.84  ? 170 LYS A CA     1 
ATOM   2684  C C      . LYS A 1 170 ? -52.825 -2.153  -39.624 1.00 36.76  ? 170 LYS A C      1 
ATOM   2685  O O      . LYS A 1 170 ? -52.984 -0.950  -39.431 1.00 40.81  ? 170 LYS A O      1 
ATOM   2686  C CB     . LYS A 1 170 ? -51.751 -3.249  -37.654 1.00 46.93  ? 170 LYS A CB     1 
ATOM   2687  C CG     . LYS A 1 170 ? -51.838 -4.210  -36.476 1.00 43.25  ? 170 LYS A CG     1 
ATOM   2688  C CD     . LYS A 1 170 ? -53.009 -3.886  -35.572 1.00 45.19  ? 170 LYS A CD     1 
ATOM   2689  C CE     . LYS A 1 170 ? -53.091 -4.842  -34.405 1.00 50.89  ? 170 LYS A CE     1 
ATOM   2690  N NZ     . LYS A 1 170 ? -54.197 -4.464  -33.487 1.00 60.30  ? 170 LYS A NZ     1 
ATOM   2691  H H      . LYS A 1 170 ? -52.765 -4.975  -39.213 1.00 55.07  ? 170 LYS A H      1 
ATOM   2692  H HA     . LYS A 1 170 ? -53.733 -2.800  -37.923 1.00 51.41  ? 170 LYS A HA     1 
ATOM   2693  H HB2    . LYS A 1 170 ? -51.028 -3.550  -38.226 1.00 56.32  ? 170 LYS A HB2    1 
ATOM   2694  H HB3    . LYS A 1 170 ? -51.545 -2.369  -37.302 1.00 56.32  ? 170 LYS A HB3    1 
ATOM   2695  H HG2    . LYS A 1 170 ? -51.953 -5.114  -36.809 1.00 51.90  ? 170 LYS A HG2    1 
ATOM   2696  H HG3    . LYS A 1 170 ? -51.024 -4.147  -35.952 1.00 51.90  ? 170 LYS A HG3    1 
ATOM   2697  H HD2    . LYS A 1 170 ? -52.915 -2.986  -35.227 1.00 54.23  ? 170 LYS A HD2    1 
ATOM   2698  H HD3    . LYS A 1 170 ? -53.835 -3.967  -36.073 1.00 54.23  ? 170 LYS A HD3    1 
ATOM   2699  H HE2    . LYS A 1 170 ? -53.260 -5.739  -34.734 1.00 61.07  ? 170 LYS A HE2    1 
ATOM   2700  H HE3    . LYS A 1 170 ? -52.258 -4.816  -33.908 1.00 61.07  ? 170 LYS A HE3    1 
ATOM   2701  H HZ1    . LYS A 1 170 ? -54.234 -5.034  -32.805 1.00 72.36  ? 170 LYS A HZ1    1 
ATOM   2702  H HZ2    . LYS A 1 170 ? -54.062 -3.643  -33.171 1.00 72.36  ? 170 LYS A HZ2    1 
ATOM   2703  H HZ3    . LYS A 1 170 ? -54.973 -4.483  -33.922 1.00 72.36  ? 170 LYS A HZ3    1 
ATOM   2704  N N      . GLY A 1 171 ? -52.464 -2.652  -40.800 1.00 41.57  ? 171 GLY A N      1 
ATOM   2705  C CA     . GLY A 1 171 ? -52.177 -1.796  -41.934 1.00 40.19  ? 171 GLY A CA     1 
ATOM   2706  C C      . GLY A 1 171 ? -50.717 -1.392  -41.951 1.00 42.37  ? 171 GLY A C      1 
ATOM   2707  O O      . GLY A 1 171 ? -50.145 -1.062  -40.913 1.00 42.96  ? 171 GLY A O      1 
ATOM   2708  H H      . GLY A 1 171 ? -52.378 -3.492  -40.965 1.00 49.88  ? 171 GLY A H      1 
ATOM   2709  H HA2    . GLY A 1 171 ? -52.377 -2.268  -42.757 1.00 48.22  ? 171 GLY A HA2    1 
ATOM   2710  H HA3    . GLY A 1 171 ? -52.724 -0.996  -41.896 1.00 48.22  ? 171 GLY A HA3    1 
ATOM   2711  N N      . ALA A 1 172 ? -50.119 -1.408  -43.137 1.00 43.08  ? 172 ALA A N      1 
ATOM   2712  C CA     . ALA A 1 172 ? -48.690 -1.155  -43.291 1.00 40.75  ? 172 ALA A CA     1 
ATOM   2713  C C      . ALA A 1 172 ? -48.263 0.198   -42.726 1.00 44.29  ? 172 ALA A C      1 
ATOM   2714  O O      . ALA A 1 172 ? -47.159 0.336   -42.201 1.00 42.56  ? 172 ALA A O      1 
ATOM   2715  C CB     . ALA A 1 172 ? -48.308 -1.247  -44.757 1.00 39.42  ? 172 ALA A CB     1 
ATOM   2716  H H      . ALA A 1 172 ? -50.525 -1.565  -43.879 1.00 51.69  ? 172 ALA A H      1 
ATOM   2717  H HA     . ALA A 1 172 ? -48.199 -1.842  -42.814 1.00 48.90  ? 172 ALA A HA     1 
ATOM   2718  H HB1    . ALA A 1 172 ? -47.355 -1.091  -44.845 1.00 47.31  ? 172 ALA A HB1    1 
ATOM   2719  H HB2    . ALA A 1 172 ? -48.531 -2.132  -45.085 1.00 47.31  ? 172 ALA A HB2    1 
ATOM   2720  H HB3    . ALA A 1 172 ? -48.802 -0.576  -45.254 1.00 47.31  ? 172 ALA A HB3    1 
ATOM   2721  N N      . GLU A 1 173 ? -49.135 1.193   -42.835 1.00 40.25  ? 173 GLU A N      1 
ATOM   2722  C CA     . GLU A 1 173 ? -48.796 2.549   -42.425 1.00 44.82  ? 173 GLU A CA     1 
ATOM   2723  C C      . GLU A 1 173 ? -48.627 2.668   -40.916 1.00 39.42  ? 173 GLU A C      1 
ATOM   2724  O O      . GLU A 1 173 ? -47.983 3.595   -40.431 1.00 41.04  ? 173 GLU A O      1 
ATOM   2725  C CB     . GLU A 1 173 ? -49.868 3.530   -42.901 1.00 51.01  ? 173 GLU A CB     1 
ATOM   2726  C CG     . GLU A 1 173 ? -49.972 3.647   -44.414 1.00 66.29  ? 173 GLU A CG     1 
ATOM   2727  C CD     . GLU A 1 173 ? -51.113 4.550   -44.852 1.00 102.03 ? 173 GLU A CD     1 
ATOM   2728  O OE1    . GLU A 1 173 ? -51.993 4.851   -44.016 1.00 96.12  ? 173 GLU A OE1    1 
ATOM   2729  O OE2    . GLU A 1 173 ? -51.130 4.960   -46.032 1.00 97.68  ? 173 GLU A OE2    1 
ATOM   2730  H H      . GLU A 1 173 ? -49.933 1.109   -43.145 1.00 48.30  ? 173 GLU A H      1 
ATOM   2731  H HA     . GLU A 1 173 ? -47.956 2.801   -42.839 1.00 53.78  ? 173 GLU A HA     1 
ATOM   2732  H HB2    . GLU A 1 173 ? -50.728 3.233   -42.565 1.00 61.21  ? 173 GLU A HB2    1 
ATOM   2733  H HB3    . GLU A 1 173 ? -49.664 4.411   -42.549 1.00 61.21  ? 173 GLU A HB3    1 
ATOM   2734  H HG2    . GLU A 1 173 ? -49.145 4.018   -44.760 1.00 79.54  ? 173 GLU A HG2    1 
ATOM   2735  H HG3    . GLU A 1 173 ? -50.125 2.766   -44.790 1.00 79.54  ? 173 GLU A HG3    1 
ATOM   2736  N N      . ASN A 1 174 ? -49.201 1.727   -40.176 1.00 37.11  ? 174 ASN A N      1 
ATOM   2737  C CA     . ASN A 1 174 ? -49.166 1.787   -38.722 1.00 38.77  ? 174 ASN A CA     1 
ATOM   2738  C C      . ASN A 1 174 ? -48.055 0.917   -38.124 1.00 42.84  ? 174 ASN A C      1 
ATOM   2739  O O      . ASN A 1 174 ? -47.950 0.775   -36.903 1.00 39.26  ? 174 ASN A O      1 
ATOM   2740  C CB     . ASN A 1 174 ? -50.528 1.381   -38.166 1.00 42.67  ? 174 ASN A CB     1 
ATOM   2741  C CG     . ASN A 1 174 ? -51.644 2.275   -38.673 1.00 44.30  ? 174 ASN A CG     1 
ATOM   2742  O OD1    . ASN A 1 174 ? -51.600 3.494   -38.504 1.00 44.89  ? 174 ASN A OD1    1 
ATOM   2743  N ND2    . ASN A 1 174 ? -52.640 1.675   -39.319 1.00 43.67  ? 174 ASN A ND2    1 
ATOM   2744  H H      . ASN A 1 174 ? -49.618 1.044   -40.490 1.00 44.53  ? 174 ASN A H      1 
ATOM   2745  H HA     . ASN A 1 174 ? -49.004 2.701   -38.442 1.00 46.52  ? 174 ASN A HA     1 
ATOM   2746  H HB2    . ASN A 1 174 ? -50.723 0.471   -38.437 1.00 51.21  ? 174 ASN A HB2    1 
ATOM   2747  H HB3    . ASN A 1 174 ? -50.508 1.443   -37.198 1.00 51.21  ? 174 ASN A HB3    1 
ATOM   2748  H HD21   . ASN A 1 174 ? -53.305 2.137   -39.608 1.00 52.40  ? 174 ASN A HD21   1 
ATOM   2749  H HD22   . ASN A 1 174 ? -52.619 0.825   -39.448 1.00 52.40  ? 174 ASN A HD22   1 
ATOM   2750  N N      . ILE A 1 175 ? -47.233 0.338   -38.994 1.00 35.55  ? 175 ILE A N      1 
ATOM   2751  C CA     . ILE A 1 175 ? -46.056 -0.412  -38.569 1.00 39.70  ? 175 ILE A CA     1 
ATOM   2752  C C      . ILE A 1 175 ? -44.816 0.459   -38.757 1.00 34.23  ? 175 ILE A C      1 
ATOM   2753  O O      . ILE A 1 175 ? -44.451 0.782   -39.883 1.00 32.22  ? 175 ILE A O      1 
ATOM   2754  C CB     . ILE A 1 175 ? -45.897 -1.720  -39.362 1.00 38.97  ? 175 ILE A CB     1 
ATOM   2755  C CG1    . ILE A 1 175 ? -47.146 -2.592  -39.199 1.00 40.12  ? 175 ILE A CG1    1 
ATOM   2756  C CG2    . ILE A 1 175 ? -44.653 -2.487  -38.895 1.00 37.11  ? 175 ILE A CG2    1 
ATOM   2757  C CD1    . ILE A 1 175 ? -47.173 -3.798  -40.110 1.00 41.24  ? 175 ILE A CD1    1 
ATOM   2758  H H      . ILE A 1 175 ? -47.334 0.363   -39.847 1.00 42.66  ? 175 ILE A H      1 
ATOM   2759  H HA     . ILE A 1 175 ? -46.128 -0.639  -37.629 1.00 47.64  ? 175 ILE A HA     1 
ATOM   2760  H HB     . ILE A 1 175 ? -45.792 -1.502  -40.301 1.00 46.76  ? 175 ILE A HB     1 
ATOM   2761  H HG12   . ILE A 1 175 ? -47.186 -2.911  -38.284 1.00 48.14  ? 175 ILE A HG12   1 
ATOM   2762  H HG13   . ILE A 1 175 ? -47.932 -2.059  -39.396 1.00 48.14  ? 175 ILE A HG13   1 
ATOM   2763  H HG21   . ILE A 1 175 ? -44.630 -3.353  -39.330 1.00 44.54  ? 175 ILE A HG21   1 
ATOM   2764  H HG22   . ILE A 1 175 ? -43.859 -1.983  -39.131 1.00 44.54  ? 175 ILE A HG22   1 
ATOM   2765  H HG23   . ILE A 1 175 ? -44.698 -2.603  -37.933 1.00 44.54  ? 175 ILE A HG23   1 
ATOM   2766  H HD11   . ILE A 1 175 ? -48.061 -4.189  -40.089 1.00 49.49  ? 175 ILE A HD11   1 
ATOM   2767  H HD12   . ILE A 1 175 ? -46.958 -3.516  -41.013 1.00 49.49  ? 175 ILE A HD12   1 
ATOM   2768  H HD13   . ILE A 1 175 ? -46.520 -4.445  -39.801 1.00 49.49  ? 175 ILE A HD13   1 
ATOM   2769  N N      . ALA A 1 176 ? -44.176 0.838   -37.654 1.00 36.97  ? 176 ALA A N      1 
ATOM   2770  C CA     . ALA A 1 176 ? -43.005 1.713   -37.714 1.00 31.01  ? 176 ALA A CA     1 
ATOM   2771  C C      . ALA A 1 176 ? -41.861 1.007   -38.437 1.00 31.57  ? 176 ALA A C      1 
ATOM   2772  O O      . ALA A 1 176 ? -41.313 1.520   -39.416 1.00 32.98  ? 176 ALA A O      1 
ATOM   2773  C CB     . ALA A 1 176 ? -42.582 2.135   -36.315 1.00 32.41  ? 176 ALA A CB     1 
ATOM   2774  H H      . ALA A 1 176 ? -44.399 0.603   -36.857 1.00 44.36  ? 176 ALA A H      1 
ATOM   2775  H HA     . ALA A 1 176 ? -43.231 2.512   -38.215 1.00 37.21  ? 176 ALA A HA     1 
ATOM   2776  H HB1    . ALA A 1 176 ? -41.771 2.662   -36.377 1.00 38.89  ? 176 ALA A HB1    1 
ATOM   2777  H HB2    . ALA A 1 176 ? -43.291 2.662   -35.915 1.00 38.89  ? 176 ALA A HB2    1 
ATOM   2778  H HB3    . ALA A 1 176 ? -42.418 1.341   -35.783 1.00 38.89  ? 176 ALA A HB3    1 
ATOM   2779  N N      . TYR A 1 177 ? -41.513 -0.180  -37.952 1.00 30.40  ? 177 TYR A N      1 
ATOM   2780  C CA     . TYR A 1 177 ? -40.560 -1.034  -38.647 1.00 30.34  ? 177 TYR A CA     1 
ATOM   2781  C C      . TYR A 1 177 ? -40.601 -2.457  -38.124 1.00 28.72  ? 177 TYR A C      1 
ATOM   2782  O O      . TYR A 1 177 ? -41.227 -2.750  -37.102 1.00 29.77  ? 177 TYR A O      1 
ATOM   2783  C CB     . TYR A 1 177 ? -39.129 -0.482  -38.533 1.00 27.81  ? 177 TYR A CB     1 
ATOM   2784  C CG     . TYR A 1 177 ? -38.612 -0.211  -37.128 1.00 29.05  ? 177 TYR A CG     1 
ATOM   2785  C CD1    . TYR A 1 177 ? -38.796 1.028   -36.532 1.00 30.43  ? 177 TYR A CD1    1 
ATOM   2786  C CD2    . TYR A 1 177 ? -37.900 -1.176  -36.418 1.00 27.21  ? 177 TYR A CD2    1 
ATOM   2787  C CE1    . TYR A 1 177 ? -38.310 1.294   -35.262 1.00 29.54  ? 177 TYR A CE1    1 
ATOM   2788  C CE2    . TYR A 1 177 ? -37.405 -0.914  -35.144 1.00 25.31  ? 177 TYR A CE2    1 
ATOM   2789  C CZ     . TYR A 1 177 ? -37.613 0.325   -34.576 1.00 27.33  ? 177 TYR A CZ     1 
ATOM   2790  O OH     . TYR A 1 177 ? -37.130 0.602   -33.319 1.00 31.38  ? 177 TYR A OH     1 
ATOM   2791  H H      . TYR A 1 177 ? -41.816 -0.514  -37.220 1.00 36.49  ? 177 TYR A H      1 
ATOM   2792  H HA     . TYR A 1 177 ? -40.793 -1.059  -39.588 1.00 36.41  ? 177 TYR A HA     1 
ATOM   2793  H HB2    . TYR A 1 177 ? -38.525 -1.121  -38.942 1.00 33.37  ? 177 TYR A HB2    1 
ATOM   2794  H HB3    . TYR A 1 177 ? -39.085 0.355   -39.021 1.00 33.37  ? 177 TYR A HB3    1 
ATOM   2795  H HD1    . TYR A 1 177 ? -39.262 1.690   -36.990 1.00 36.52  ? 177 TYR A HD1    1 
ATOM   2796  H HD2    . TYR A 1 177 ? -37.755 -2.011  -36.801 1.00 32.65  ? 177 TYR A HD2    1 
ATOM   2797  H HE1    . TYR A 1 177 ? -38.447 2.129   -34.877 1.00 35.45  ? 177 TYR A HE1    1 
ATOM   2798  H HE2    . TYR A 1 177 ? -36.936 -1.569  -34.680 1.00 30.38  ? 177 TYR A HE2    1 
ATOM   2799  H HH     . TYR A 1 177 ? -36.727 -0.068  -33.012 1.00 37.66  ? 177 TYR A HH     1 
ATOM   2800  N N      . ILE A 1 178 ? -39.946 -3.341  -38.863 1.00 29.99  ? 178 ILE A N      1 
ATOM   2801  C CA     . ILE A 1 178 ? -39.650 -4.676  -38.385 1.00 27.47  ? 178 ILE A CA     1 
ATOM   2802  C C      . ILE A 1 178 ? -38.264 -4.655  -37.744 1.00 28.80  ? 178 ILE A C      1 
ATOM   2803  O O      . ILE A 1 178 ? -37.305 -4.163  -38.338 1.00 25.79  ? 178 ILE A O      1 
ATOM   2804  C CB     . ILE A 1 178 ? -39.693 -5.705  -39.521 1.00 29.56  ? 178 ILE A CB     1 
ATOM   2805  C CG1    . ILE A 1 178 ? -41.049 -5.653  -40.243 1.00 32.74  ? 178 ILE A CG1    1 
ATOM   2806  C CG2    . ILE A 1 178 ? -39.375 -7.102  -38.997 1.00 27.76  ? 178 ILE A CG2    1 
ATOM   2807  C CD1    . ILE A 1 178 ? -42.260 -5.827  -39.345 1.00 35.94  ? 178 ILE A CD1    1 
ATOM   2808  H H      . ILE A 1 178 ? -39.659 -3.186  -39.659 1.00 35.98  ? 178 ILE A H      1 
ATOM   2809  H HA     . ILE A 1 178 ? -40.296 -4.934  -37.712 1.00 32.96  ? 178 ILE A HA     1 
ATOM   2810  H HB     . ILE A 1 178 ? -39.006 -5.466  -40.163 1.00 35.47  ? 178 ILE A HB     1 
ATOM   2811  H HG12   . ILE A 1 178 ? -41.133 -4.795  -40.687 1.00 39.28  ? 178 ILE A HG12   1 
ATOM   2812  H HG13   . ILE A 1 178 ? -41.073 -6.364  -40.902 1.00 39.28  ? 178 ILE A HG13   1 
ATOM   2813  H HG21   . ILE A 1 178 ? -39.590 -7.751  -39.685 1.00 33.31  ? 178 ILE A HG21   1 
ATOM   2814  H HG22   . ILE A 1 178 ? -38.431 -7.153  -38.778 1.00 33.31  ? 178 ILE A HG22   1 
ATOM   2815  H HG23   . ILE A 1 178 ? -39.910 -7.271  -38.206 1.00 33.31  ? 178 ILE A HG23   1 
ATOM   2816  H HD11   . ILE A 1 178 ? -43.056 -5.875  -39.897 1.00 43.13  ? 178 ILE A HD11   1 
ATOM   2817  H HD12   . ILE A 1 178 ? -42.160 -6.646  -38.835 1.00 43.13  ? 178 ILE A HD12   1 
ATOM   2818  H HD13   . ILE A 1 178 ? -42.322 -5.068  -38.744 1.00 43.13  ? 178 ILE A HD13   1 
ATOM   2819  N N      . CYS A 1 179 ? -38.180 -5.177  -36.525 1.00 24.55  ? 179 CYS A N      1 
ATOM   2820  C CA     . CYS A 1 179 ? -36.922 -5.283  -35.802 1.00 26.08  ? 179 CYS A CA     1 
ATOM   2821  C C      . CYS A 1 179 ? -36.437 -6.727  -35.831 1.00 25.92  ? 179 CYS A C      1 
ATOM   2822  O O      . CYS A 1 179 ? -36.904 -7.560  -35.059 1.00 29.49  ? 179 CYS A O      1 
ATOM   2823  C CB     . CYS A 1 179 ? -37.091 -4.806  -34.360 1.00 28.42  ? 179 CYS A CB     1 
ATOM   2824  S SG     . CYS A 1 179 ? -35.532 -4.707  -33.445 1.00 34.54  ? 179 CYS A SG     1 
ATOM   2825  H H      . CYS A 1 179 ? -38.854 -5.483  -36.088 1.00 29.46  ? 179 CYS A H      1 
ATOM   2826  H HA     . CYS A 1 179 ? -36.252 -4.726  -36.223 1.00 31.30  ? 179 CYS A HA     1 
ATOM   2827  H HB2    . CYS A 1 179 ? -37.486 -3.920  -34.368 1.00 34.11  ? 179 CYS A HB2    1 
ATOM   2828  H HB3    . CYS A 1 179 ? -37.674 -5.422  -33.890 1.00 34.11  ? 179 CYS A HB3    1 
ATOM   2829  H HG     . CYS A 1 179 ? -35.756 -4.329  -32.328 1.00 41.45  ? 179 CYS A HG     1 
ATOM   2830  N N      . LEU A 1 180 ? -35.515 -7.018  -36.742 1.00 25.74  ? 180 LEU A N      1 
ATOM   2831  C CA     . LEU A 1 180 ? -35.012 -8.372  -36.922 1.00 22.62  ? 180 LEU A CA     1 
ATOM   2832  C C      . LEU A 1 180 ? -33.706 -8.533  -36.152 1.00 24.69  ? 180 LEU A C      1 
ATOM   2833  O O      . LEU A 1 180 ? -32.694 -7.925  -36.498 1.00 23.89  ? 180 LEU A O      1 
ATOM   2834  C CB     . LEU A 1 180 ? -34.809 -8.670  -38.413 1.00 25.64  ? 180 LEU A CB     1 
ATOM   2835  C CG     . LEU A 1 180 ? -34.604 -10.132 -38.819 1.00 28.04  ? 180 LEU A CG     1 
ATOM   2836  C CD1    . LEU A 1 180 ? -35.015 -10.353 -40.280 1.00 27.10  ? 180 LEU A CD1    1 
ATOM   2837  C CD2    . LEU A 1 180 ? -33.165 -10.564 -38.624 1.00 28.74  ? 180 LEU A CD2    1 
ATOM   2838  H H      . LEU A 1 180 ? -35.162 -6.442  -37.274 1.00 30.89  ? 180 LEU A H      1 
ATOM   2839  H HA     . LEU A 1 180 ? -35.652 -9.011  -36.573 1.00 27.15  ? 180 LEU A HA     1 
ATOM   2840  H HB2    . LEU A 1 180 ? -35.590 -8.350  -38.891 1.00 30.77  ? 180 LEU A HB2    1 
ATOM   2841  H HB3    . LEU A 1 180 ? -34.030 -8.178  -38.714 1.00 30.77  ? 180 LEU A HB3    1 
ATOM   2842  H HG     . LEU A 1 180 ? -35.164 -10.695 -38.262 1.00 33.65  ? 180 LEU A HG     1 
ATOM   2843  H HD11   . LEU A 1 180 ? -34.872 -11.284 -40.511 1.00 32.52  ? 180 LEU A HD11   1 
ATOM   2844  H HD12   . LEU A 1 180 ? -35.953 -10.127 -40.382 1.00 32.52  ? 180 LEU A HD12   1 
ATOM   2845  H HD13   . LEU A 1 180 ? -34.474 -9.784  -40.849 1.00 32.52  ? 180 LEU A HD13   1 
ATOM   2846  H HD21   . LEU A 1 180 ? -33.035 -11.425 -39.051 1.00 34.49  ? 180 LEU A HD21   1 
ATOM   2847  H HD22   . LEU A 1 180 ? -32.579 -9.904  -39.027 1.00 34.49  ? 180 LEU A HD22   1 
ATOM   2848  H HD23   . LEU A 1 180 ? -32.981 -10.635 -37.675 1.00 34.49  ? 180 LEU A HD23   1 
ATOM   2849  N N      . ALA A 1 181 ? -33.738 -9.341  -35.102 1.00 24.09  ? 181 ALA A N      1 
ATOM   2850  C CA     . ALA A 1 181 ? -32.557 -9.579  -34.278 1.00 22.36  ? 181 ALA A CA     1 
ATOM   2851  C C      . ALA A 1 181 ? -31.747 -10.769 -34.786 1.00 25.85  ? 181 ALA A C      1 
ATOM   2852  O O      . ALA A 1 181 ? -32.315 -11.793 -35.162 1.00 22.33  ? 181 ALA A O      1 
ATOM   2853  C CB     . ALA A 1 181 ? -32.968 -9.803  -32.824 1.00 28.59  ? 181 ALA A CB     1 
ATOM   2854  H H      . ALA A 1 181 ? -34.437 -9.769  -34.841 1.00 28.90  ? 181 ALA A H      1 
ATOM   2855  H HA     . ALA A 1 181 ? -31.988 -8.796  -34.305 1.00 26.84  ? 181 ALA A HA     1 
ATOM   2856  H HB1    . ALA A 1 181 ? -32.172 -9.959  -32.292 1.00 34.30  ? 181 ALA A HB1    1 
ATOM   2857  H HB2    . ALA A 1 181 ? -33.432 -9.014  -32.502 1.00 34.30  ? 181 ALA A HB2    1 
ATOM   2858  H HB3    . ALA A 1 181 ? -33.554 -10.574 -32.777 1.00 34.30  ? 181 ALA A HB3    1 
ATOM   2859  N N      . VAL A 1 182 ? -30.424 -10.610 -34.816 1.00 23.34  ? 182 VAL A N      1 
ATOM   2860  C CA     . VAL A 1 182 ? -29.505 -11.713 -35.081 1.00 21.41  ? 182 VAL A CA     1 
ATOM   2861  C C      . VAL A 1 182 ? -28.352 -11.688 -34.063 1.00 26.94  ? 182 VAL A C      1 
ATOM   2862  O O      . VAL A 1 182 ? -27.691 -10.656 -33.903 1.00 26.18  ? 182 VAL A O      1 
ATOM   2863  C CB     . VAL A 1 182 ? -28.933 -11.656 -36.510 1.00 22.89  ? 182 VAL A CB     1 
ATOM   2864  C CG1    . VAL A 1 182 ? -30.010 -11.988 -37.533 1.00 25.87  ? 182 VAL A CG1    1 
ATOM   2865  C CG2    . VAL A 1 182 ? -28.331 -10.281 -36.823 1.00 24.65  ? 182 VAL A CG2    1 
ATOM   2866  H H      . VAL A 1 182 ? -30.029 -9.858  -34.683 1.00 28.00  ? 182 VAL A H      1 
ATOM   2867  H HA     . VAL A 1 182 ? -29.995 -12.541 -35.006 1.00 25.69  ? 182 VAL A HA     1 
ATOM   2868  H HB     . VAL A 1 182 ? -28.228 -12.317 -36.593 1.00 27.47  ? 182 VAL A HB     1 
ATOM   2869  H HG11   . VAL A 1 182 ? -29.626 -11.934 -38.422 1.00 31.05  ? 182 VAL A HG11   1 
ATOM   2870  H HG12   . VAL A 1 182 ? -30.337 -12.886 -37.366 1.00 31.05  ? 182 VAL A HG12   1 
ATOM   2871  H HG13   . VAL A 1 182 ? -30.735 -11.350 -37.446 1.00 31.05  ? 182 VAL A HG13   1 
ATOM   2872  H HG21   . VAL A 1 182 ? -28.142 -10.232 -37.773 1.00 29.58  ? 182 VAL A HG21   1 
ATOM   2873  H HG22   . VAL A 1 182 ? -28.965 -9.589  -36.580 1.00 29.58  ? 182 VAL A HG22   1 
ATOM   2874  H HG23   . VAL A 1 182 ? -27.510 -10.170 -36.320 1.00 29.58  ? 182 VAL A HG23   1 
ATOM   2875  N N      . THR A 1 183 ? -28.125 -12.764 -33.312 1.00 30.60  ? 183 THR A N      1 
ATOM   2876  C CA     . THR A 1 183 ? -29.031 -13.890 -33.117 1.00 26.38  ? 183 THR A CA     1 
ATOM   2877  C C      . THR A 1 183 ? -30.183 -13.503 -32.188 1.00 27.98  ? 183 THR A C      1 
ATOM   2878  O O      . THR A 1 183 ? -30.274 -12.358 -31.758 1.00 26.73  ? 183 THR A O      1 
ATOM   2879  C CB     . THR A 1 183 ? -28.274 -15.070 -32.503 1.00 22.29  ? 183 THR A CB     1 
ATOM   2880  O OG1    . THR A 1 183 ? -27.636 -14.632 -31.298 1.00 22.10  ? 183 THR A OG1    1 
ATOM   2881  C CG2    . THR A 1 183 ? -27.213 -15.585 -33.450 1.00 21.17  ? 183 THR A CG2    1 
ATOM   2882  H H      . THR A 1 183 ? -27.393 -12.867 -32.874 1.00 36.72  ? 183 THR A H      1 
ATOM   2883  H HA     . THR A 1 183 ? -29.394 -14.188 -33.964 1.00 31.66  ? 183 THR A HA     1 
ATOM   2884  H HB     . THR A 1 183 ? -28.888 -15.793 -32.303 1.00 26.75  ? 183 THR A HB     1 
ATOM   2885  H HG1    . THR A 1 183 ? -27.217 -15.270 -30.947 1.00 26.52  ? 183 THR A HG1    1 
ATOM   2886  H HG21   . THR A 1 183 ? -26.758 -16.346 -33.056 1.00 25.41  ? 183 THR A HG21   1 
ATOM   2887  H HG22   . THR A 1 183 ? -27.621 -15.860 -34.286 1.00 25.41  ? 183 THR A HG22   1 
ATOM   2888  H HG23   . THR A 1 183 ? -26.563 -14.888 -33.631 1.00 25.41  ? 183 THR A HG23   1 
ATOM   2889  N N      . VAL A 1 184 ? -31.032 -14.471 -31.839 1.00 26.90  ? 184 VAL A N      1 
ATOM   2890  C CA     . VAL A 1 184 ? -32.178 -14.214 -30.962 1.00 27.15  ? 184 VAL A CA     1 
ATOM   2891  C C      . VAL A 1 184 ? -31.870 -14.652 -29.534 1.00 31.63  ? 184 VAL A C      1 
ATOM   2892  O O      . VAL A 1 184 ? -31.736 -15.840 -29.238 1.00 27.94  ? 184 VAL A O      1 
ATOM   2893  C CB     . VAL A 1 184 ? -33.451 -14.925 -31.470 1.00 24.44  ? 184 VAL A CB     1 
ATOM   2894  C CG1    . VAL A 1 184 ? -34.606 -14.774 -30.474 1.00 29.40  ? 184 VAL A CG1    1 
ATOM   2895  C CG2    . VAL A 1 184 ? -33.860 -14.358 -32.814 1.00 25.47  ? 184 VAL A CG2    1 
ATOM   2896  H H      . VAL A 1 184 ? -30.967 -15.289 -32.098 1.00 32.28  ? 184 VAL A H      1 
ATOM   2897  H HA     . VAL A 1 184 ? -32.365 -13.263 -30.946 1.00 32.58  ? 184 VAL A HA     1 
ATOM   2898  H HB     . VAL A 1 184 ? -33.267 -15.871 -31.582 1.00 29.32  ? 184 VAL A HB     1 
ATOM   2899  H HG11   . VAL A 1 184 ? -35.437 -15.000 -30.920 1.00 35.28  ? 184 VAL A HG11   1 
ATOM   2900  H HG12   . VAL A 1 184 ? -34.461 -15.373 -29.725 1.00 35.28  ? 184 VAL A HG12   1 
ATOM   2901  H HG13   . VAL A 1 184 ? -34.638 -13.855 -30.165 1.00 35.28  ? 184 VAL A HG13   1 
ATOM   2902  H HG21   . VAL A 1 184 ? -34.662 -14.811 -33.117 1.00 30.57  ? 184 VAL A HG21   1 
ATOM   2903  H HG22   . VAL A 1 184 ? -34.033 -13.409 -32.716 1.00 30.57  ? 184 VAL A HG22   1 
ATOM   2904  H HG23   . VAL A 1 184 ? -33.140 -14.500 -33.449 1.00 30.57  ? 184 VAL A HG23   1 
ATOM   2905  N N      . ASN A 1 185 ? -31.780 -13.665 -28.654 1.00 28.40  ? 185 ASN A N      1 
ATOM   2906  C CA     . ASN A 1 185 ? -31.322 -13.859 -27.285 1.00 33.77  ? 185 ASN A CA     1 
ATOM   2907  C C      . ASN A 1 185 ? -32.289 -14.668 -26.419 1.00 35.24  ? 185 ASN A C      1 
ATOM   2908  O O      . ASN A 1 185 ? -31.885 -15.611 -25.728 1.00 34.72  ? 185 ASN A O      1 
ATOM   2909  C CB     . ASN A 1 185 ? -31.080 -12.486 -26.654 1.00 40.31  ? 185 ASN A CB     1 
ATOM   2910  C CG     . ASN A 1 185 ? -30.354 -12.569 -25.336 1.00 57.39  ? 185 ASN A CG     1 
ATOM   2911  O OD1    . ASN A 1 185 ? -30.970 -12.548 -24.270 1.00 63.36  ? 185 ASN A OD1    1 
ATOM   2912  N ND2    . ASN A 1 185 ? -29.030 -12.657 -25.400 1.00 60.98  ? 185 ASN A ND2    1 
ATOM   2913  H H      . ASN A 1 185 ? -31.985 -12.849 -28.832 1.00 34.08  ? 185 ASN A H      1 
ATOM   2914  H HA     . ASN A 1 185 ? -30.475 -14.331 -27.303 1.00 40.52  ? 185 ASN A HA     1 
ATOM   2915  H HB2    . ASN A 1 185 ? -30.543 -11.951 -27.259 1.00 48.38  ? 185 ASN A HB2    1 
ATOM   2916  H HB3    . ASN A 1 185 ? -31.935 -12.055 -26.499 1.00 48.38  ? 185 ASN A HB3    1 
ATOM   2917  H HD21   . ASN A 1 185 ? -28.560 -12.596 -24.683 1.00 73.18  ? 185 ASN A HD21   1 
ATOM   2918  H HD22   . ASN A 1 185 ? -28.643 -12.771 -26.159 1.00 73.18  ? 185 ASN A HD22   1 
ATOM   2919  N N      . LEU A 1 186 ? -33.564 -14.297 -26.450 1.00 33.12  ? 186 LEU A N      1 
ATOM   2920  C CA     . LEU A 1 186 ? -34.560 -14.910 -25.571 1.00 40.47  ? 186 LEU A CA     1 
ATOM   2921  C C      . LEU A 1 186 ? -34.796 -16.388 -25.872 1.00 42.60  ? 186 LEU A C      1 
ATOM   2922  O O      . LEU A 1 186 ? -35.357 -17.101 -25.039 1.00 38.20  ? 186 LEU A O      1 
ATOM   2923  C CB     . LEU A 1 186 ? -35.888 -14.158 -25.673 1.00 37.24  ? 186 LEU A CB     1 
ATOM   2924  C CG     . LEU A 1 186 ? -36.622 -13.805 -24.383 1.00 46.25  ? 186 LEU A CG     1 
ATOM   2925  C CD1    . LEU A 1 186 ? -35.726 -13.054 -23.397 1.00 60.81  ? 186 LEU A CD1    1 
ATOM   2926  C CD2    . LEU A 1 186 ? -37.841 -12.969 -24.728 1.00 45.23  ? 186 LEU A CD2    1 
ATOM   2927  H H      . LEU A 1 186 ? -33.880 -13.692 -26.973 1.00 39.75  ? 186 LEU A H      1 
ATOM   2928  H HA     . LEU A 1 186 ? -34.244 -14.848 -24.657 1.00 48.56  ? 186 LEU A HA     1 
ATOM   2929  H HB2    . LEU A 1 186 ? -35.729 -13.323 -26.132 1.00 44.69  ? 186 LEU A HB2    1 
ATOM   2930  H HB3    . LEU A 1 186 ? -36.495 -14.698 -26.203 1.00 44.69  ? 186 LEU A HB3    1 
ATOM   2931  H HG     . LEU A 1 186 ? -36.926 -14.621 -23.955 1.00 55.50  ? 186 LEU A HG     1 
ATOM   2932  H HD11   . LEU A 1 186 ? -36.284 -12.634 -22.723 1.00 72.97  ? 186 LEU A HD11   1 
ATOM   2933  H HD12   . LEU A 1 186 ? -35.118 -13.682 -22.977 1.00 72.97  ? 186 LEU A HD12   1 
ATOM   2934  H HD13   . LEU A 1 186 ? -35.225 -12.377 -23.878 1.00 72.97  ? 186 LEU A HD13   1 
ATOM   2935  H HD21   . LEU A 1 186 ? -38.318 -12.755 -23.911 1.00 54.28  ? 186 LEU A HD21   1 
ATOM   2936  H HD22   . LEU A 1 186 ? -37.551 -12.153 -25.165 1.00 54.28  ? 186 LEU A HD22   1 
ATOM   2937  H HD23   . LEU A 1 186 ? -38.414 -13.478 -25.323 1.00 54.28  ? 186 LEU A HD23   1 
ATOM   2938  N N      . ALA A 1 187 ? -34.380 -16.843 -27.056 1.00 32.33  ? 187 ALA A N      1 
ATOM   2939  C CA     . ALA A 1 187 ? -34.528 -18.253 -27.429 1.00 35.70  ? 187 ALA A CA     1 
ATOM   2940  C C      . ALA A 1 187 ? -33.242 -19.037 -27.155 1.00 31.85  ? 187 ALA A C      1 
ATOM   2941  O O      . ALA A 1 187 ? -33.146 -20.225 -27.464 1.00 26.73  ? 187 ALA A O      1 
ATOM   2942  C CB     . ALA A 1 187 ? -34.921 -18.379 -28.899 1.00 33.21  ? 187 ALA A CB     1 
ATOM   2943  H H      . ALA A 1 187 ? -34.010 -16.357 -27.661 1.00 38.80  ? 187 ALA A H      1 
ATOM   2944  H HA     . ALA A 1 187 ? -35.237 -18.653 -26.903 1.00 42.84  ? 187 ALA A HA     1 
ATOM   2945  H HB1    . ALA A 1 187 ? -35.014 -19.319 -29.121 1.00 39.85  ? 187 ALA A HB1    1 
ATOM   2946  H HB2    . ALA A 1 187 ? -35.764 -17.920 -29.040 1.00 39.85  ? 187 ALA A HB2    1 
ATOM   2947  H HB3    . ALA A 1 187 ? -34.229 -17.976 -29.446 1.00 39.85  ? 187 ALA A HB3    1 
ATOM   2948  N N      . GLY A 1 188 ? -32.252 -18.360 -26.583 1.00 29.75  ? 188 GLY A N      1 
ATOM   2949  C CA     . GLY A 1 188 ? -31.004 -18.997 -26.206 1.00 29.80  ? 188 GLY A CA     1 
ATOM   2950  C C      . GLY A 1 188 ? -29.870 -18.705 -27.170 1.00 28.66  ? 188 GLY A C      1 
ATOM   2951  O O      . GLY A 1 188 ? -28.852 -19.394 -27.143 1.00 31.23  ? 188 GLY A O      1 
ATOM   2952  H H      . GLY A 1 188 ? -32.278 -17.521 -26.400 1.00 35.69  ? 188 GLY A H      1 
ATOM   2953  H HA2    . GLY A 1 188 ? -30.743 -18.679 -25.329 1.00 35.76  ? 188 GLY A HA2    1 
ATOM   2954  H HA3    . GLY A 1 188 ? -31.122 -19.958 -26.155 1.00 35.76  ? 188 GLY A HA3    1 
ATOM   2955  N N      . GLY A 1 189 ? -30.040 -17.690 -28.017 1.00 26.46  ? 189 GLY A N      1 
ATOM   2956  C CA     . GLY A 1 189 ? -29.002 -17.280 -28.954 1.00 24.29  ? 189 GLY A CA     1 
ATOM   2957  C C      . GLY A 1 189 ? -29.143 -17.991 -30.290 1.00 20.43  ? 189 GLY A C      1 
ATOM   2958  O O      . GLY A 1 189 ? -28.174 -18.535 -30.826 1.00 20.23  ? 189 GLY A O      1 
ATOM   2959  H H      . GLY A 1 189 ? -30.757 -17.218 -28.068 1.00 31.75  ? 189 GLY A H      1 
ATOM   2960  H HA2    . GLY A 1 189 ? -29.062 -16.324 -29.106 1.00 29.14  ? 189 GLY A HA2    1 
ATOM   2961  H HA3    . GLY A 1 189 ? -28.127 -17.479 -28.586 1.00 29.14  ? 189 GLY A HA3    1 
ATOM   2962  N N      . GLN A 1 190 ? -30.355 -17.963 -30.836 1.00 21.22  ? 190 GLN A N      1 
ATOM   2963  C CA     . GLN A 1 190 ? -30.693 -18.772 -32.004 1.00 23.63  ? 190 GLN A CA     1 
ATOM   2964  C C      . GLN A 1 190 ? -30.579 -17.963 -33.285 1.00 21.01  ? 190 GLN A C      1 
ATOM   2965  O O      . GLN A 1 190 ? -30.971 -16.797 -33.326 1.00 20.65  ? 190 GLN A O      1 
ATOM   2966  C CB     . GLN A 1 190 ? -32.106 -19.338 -31.880 1.00 26.23  ? 190 GLN A CB     1 
ATOM   2967  C CG     . GLN A 1 190 ? -32.352 -20.108 -30.588 1.00 26.33  ? 190 GLN A CG     1 
ATOM   2968  C CD     . GLN A 1 190 ? -31.497 -21.349 -30.463 1.00 25.22  ? 190 GLN A CD     1 
ATOM   2969  O OE1    . GLN A 1 190 ? -31.073 -21.947 -31.460 1.00 23.12  ? 190 GLN A OE1    1 
ATOM   2970  N NE2    . GLN A 1 190 ? -31.244 -21.757 -29.226 1.00 25.16  ? 190 GLN A NE2    1 
ATOM   2971  H H      . GLN A 1 190 ? -31.005 -17.480 -30.547 1.00 25.47  ? 190 GLN A H      1 
ATOM   2972  H HA     . GLN A 1 190 ? -30.082 -19.521 -32.041 1.00 28.35  ? 190 GLN A HA     1 
ATOM   2973  H HB2    . GLN A 1 190 ? -32.740 -18.604 -31.912 1.00 31.48  ? 190 GLN A HB2    1 
ATOM   2974  H HB3    . GLN A 1 190 ? -32.267 -19.943 -32.621 1.00 31.48  ? 190 GLN A HB3    1 
ATOM   2975  H HG2    . GLN A 1 190 ? -32.154 -19.532 -29.834 1.00 31.60  ? 190 GLN A HG2    1 
ATOM   2976  H HG3    . GLN A 1 190 ? -33.282 -20.383 -30.558 1.00 31.60  ? 190 GLN A HG3    1 
ATOM   2977  H HE21   . GLN A 1 190 ? -31.561 -21.321 -28.556 1.00 30.19  ? 190 GLN A HE21   1 
ATOM   2978  H HE22   . GLN A 1 190 ? -30.763 -22.457 -29.094 1.00 30.19  ? 190 GLN A HE22   1 
ATOM   2979  N N      . PRO A 1 191 ? -30.051 -18.590 -34.346 1.00 19.96  ? 191 PRO A N      1 
ATOM   2980  C CA     . PRO A 1 191 ? -29.823 -17.836 -35.577 1.00 22.63  ? 191 PRO A CA     1 
ATOM   2981  C C      . PRO A 1 191 ? -31.057 -17.681 -36.478 1.00 24.21  ? 191 PRO A C      1 
ATOM   2982  O O      . PRO A 1 191 ? -32.092 -18.328 -36.296 1.00 21.15  ? 191 PRO A O      1 
ATOM   2983  C CB     . PRO A 1 191 ? -28.744 -18.662 -36.279 1.00 21.30  ? 191 PRO A CB     1 
ATOM   2984  C CG     . PRO A 1 191 ? -29.027 -20.063 -35.852 1.00 22.53  ? 191 PRO A CG     1 
ATOM   2985  C CD     . PRO A 1 191 ? -29.503 -19.958 -34.428 1.00 22.93  ? 191 PRO A CD     1 
ATOM   2986  H HA     . PRO A 1 191 ? -29.468 -16.960 -35.366 1.00 27.16  ? 191 PRO A HA     1 
ATOM   2987  H HB2    . PRO A 1 191 ? -28.830 -18.569 -37.241 1.00 25.56  ? 191 PRO A HB2    1 
ATOM   2988  H HB3    . PRO A 1 191 ? -27.865 -18.380 -35.980 1.00 25.56  ? 191 PRO A HB3    1 
ATOM   2989  H HG2    . PRO A 1 191 ? -29.719 -20.441 -36.416 1.00 27.04  ? 191 PRO A HG2    1 
ATOM   2990  H HG3    . PRO A 1 191 ? -28.217 -20.592 -35.904 1.00 27.04  ? 191 PRO A HG3    1 
ATOM   2991  H HD2    . PRO A 1 191 ? -30.198 -20.612 -34.255 1.00 27.52  ? 191 PRO A HD2    1 
ATOM   2992  H HD3    . PRO A 1 191 ? -28.758 -20.061 -33.816 1.00 27.52  ? 191 PRO A HD3    1 
ATOM   2993  N N      . VAL A 1 192 ? -30.906 -16.782 -37.443 1.00 21.03  ? 192 VAL A N      1 
ATOM   2994  C CA     . VAL A 1 192 ? -31.893 -16.494 -38.478 1.00 21.19  ? 192 VAL A CA     1 
ATOM   2995  C C      . VAL A 1 192 ? -31.254 -16.829 -39.822 1.00 21.20  ? 192 VAL A C      1 
ATOM   2996  O O      . VAL A 1 192 ? -30.107 -16.452 -40.067 1.00 22.13  ? 192 VAL A O      1 
ATOM   2997  C CB     . VAL A 1 192 ? -32.317 -15.014 -38.455 1.00 19.81  ? 192 VAL A CB     1 
ATOM   2998  C CG1    . VAL A 1 192 ? -33.327 -14.717 -39.554 1.00 23.34  ? 192 VAL A CG1    1 
ATOM   2999  C CG2    . VAL A 1 192 ? -32.876 -14.637 -37.085 1.00 21.70  ? 192 VAL A CG2    1 
ATOM   3000  H H      . VAL A 1 192 ? -30.198 -16.299 -37.522 1.00 25.23  ? 192 VAL A H      1 
ATOM   3001  H HA     . VAL A 1 192 ? -32.678 -17.048 -38.354 1.00 25.42  ? 192 VAL A HA     1 
ATOM   3002  H HB     . VAL A 1 192 ? -31.535 -14.464 -38.617 1.00 23.78  ? 192 VAL A HB     1 
ATOM   3003  H HG11   . VAL A 1 192 ? -33.680 -13.823 -39.422 1.00 28.01  ? 192 VAL A HG11   1 
ATOM   3004  H HG12   . VAL A 1 192 ? -32.887 -14.773 -40.416 1.00 28.01  ? 192 VAL A HG12   1 
ATOM   3005  H HG13   . VAL A 1 192 ? -34.047 -15.365 -39.505 1.00 28.01  ? 192 VAL A HG13   1 
ATOM   3006  H HG21   . VAL A 1 192 ? -33.183 -13.717 -37.112 1.00 26.04  ? 192 VAL A HG21   1 
ATOM   3007  H HG22   . VAL A 1 192 ? -33.616 -15.227 -36.874 1.00 26.04  ? 192 VAL A HG22   1 
ATOM   3008  H HG23   . VAL A 1 192 ? -32.176 -14.733 -36.420 1.00 26.04  ? 192 VAL A HG23   1 
ATOM   3009  N N      . SER A 1 193 ? -31.984 -17.518 -40.694 1.00 20.90  ? 193 SER A N      1 
ATOM   3010  C CA     . SER A 1 193 ? -31.460 -17.901 -42.009 1.00 21.53  ? 193 SER A CA     1 
ATOM   3011  C C      . SER A 1 193 ? -31.474 -16.748 -43.014 1.00 19.88  ? 193 SER A C      1 
ATOM   3012  O O      . SER A 1 193 ? -32.259 -15.809 -42.894 1.00 21.20  ? 193 SER A O      1 
ATOM   3013  C CB     . SER A 1 193 ? -32.275 -19.075 -42.579 1.00 24.24  ? 193 SER A CB     1 
ATOM   3014  O OG     . SER A 1 193 ? -33.610 -18.666 -42.800 1.00 23.60  ? 193 SER A OG     1 
ATOM   3015  H H      . SER A 1 193 ? -32.791 -17.779 -40.550 1.00 25.08  ? 193 SER A H      1 
ATOM   3016  H HA     . SER A 1 193 ? -30.542 -18.198 -41.908 1.00 25.83  ? 193 SER A HA     1 
ATOM   3017  H HB2    . SER A 1 193 ? -31.885 -19.357 -43.421 1.00 29.09  ? 193 SER A HB2    1 
ATOM   3018  H HB3    . SER A 1 193 ? -32.267 -19.808 -41.944 1.00 29.09  ? 193 SER A HB3    1 
ATOM   3019  H HG     . SER A 1 193 ? -34.057 -19.303 -43.116 1.00 28.33  ? 193 SER A HG     1 
ATOM   3020  N N      . MET A 1 194 ? -30.614 -16.828 -44.025 1.00 21.20  ? 194 MET A N      1 
ATOM   3021  C CA     . MET A 1 194 ? -30.640 -15.847 -45.105 1.00 23.41  ? 194 MET A CA     1 
ATOM   3022  C C      . MET A 1 194 ? -32.003 -15.882 -45.809 1.00 23.12  ? 194 MET A C      1 
ATOM   3023  O O      . MET A 1 194 ? -32.562 -14.840 -46.175 1.00 23.26  ? 194 MET A O      1 
ATOM   3024  C CB     . MET A 1 194 ? -29.518 -16.110 -46.109 1.00 20.34  ? 194 MET A CB     1 
ATOM   3025  C CG     . MET A 1 194 ? -29.273 -14.942 -47.051 1.00 26.78  ? 194 MET A CG     1 
ATOM   3026  S SD     . MET A 1 194 ? -28.369 -13.613 -46.225 1.00 23.81  ? 194 MET A SD     1 
ATOM   3027  C CE     . MET A 1 194 ? -26.726 -14.304 -46.200 1.00 22.67  ? 194 MET A CE     1 
ATOM   3028  H H      . MET A 1 194 ? -30.010 -17.435 -44.109 1.00 25.44  ? 194 MET A H      1 
ATOM   3029  H HA     . MET A 1 194 ? -30.503 -14.963 -44.730 1.00 28.09  ? 194 MET A HA     1 
ATOM   3030  H HB2    . MET A 1 194 ? -28.696 -16.282 -45.624 1.00 24.41  ? 194 MET A HB2    1 
ATOM   3031  H HB3    . MET A 1 194 ? -29.752 -16.883 -46.647 1.00 24.41  ? 194 MET A HB3    1 
ATOM   3032  H HG2    . MET A 1 194 ? -28.746 -15.245 -47.807 1.00 32.14  ? 194 MET A HG2    1 
ATOM   3033  H HG3    . MET A 1 194 ? -30.124 -14.589 -47.355 1.00 32.14  ? 194 MET A HG3    1 
ATOM   3034  H HE1    . MET A 1 194 ? -26.118 -13.656 -45.811 1.00 27.21  ? 194 MET A HE1    1 
ATOM   3035  H HE2    . MET A 1 194 ? -26.731 -15.114 -45.667 1.00 27.21  ? 194 MET A HE2    1 
ATOM   3036  H HE3    . MET A 1 194 ? -26.455 -14.507 -47.109 1.00 27.21  ? 194 MET A HE3    1 
ATOM   3037  N N      . ALA A 1 195 ? -32.538 -17.088 -45.985 1.00 25.16  ? 195 ALA A N      1 
ATOM   3038  C CA     . ALA A 1 195 ? -33.833 -17.263 -46.641 1.00 25.91  ? 195 ALA A CA     1 
ATOM   3039  C C      . ALA A 1 195 ? -34.907 -16.469 -45.918 1.00 26.51  ? 195 ALA A C      1 
ATOM   3040  O O      . ALA A 1 195 ? -35.738 -15.826 -46.549 1.00 26.39  ? 195 ALA A O      1 
ATOM   3041  C CB     . ALA A 1 195 ? -34.211 -18.738 -46.697 1.00 27.17  ? 195 ALA A CB     1 
ATOM   3042  H H      . ALA A 1 195 ? -32.170 -17.824 -45.733 1.00 30.20  ? 195 ALA A H      1 
ATOM   3043  H HA     . ALA A 1 195 ? -33.775 -16.932 -47.551 1.00 31.09  ? 195 ALA A HA     1 
ATOM   3044  H HB1    . ALA A 1 195 ? -35.072 -18.827 -47.136 1.00 32.61  ? 195 ALA A HB1    1 
ATOM   3045  H HB2    . ALA A 1 195 ? -33.533 -19.218 -47.198 1.00 32.61  ? 195 ALA A HB2    1 
ATOM   3046  H HB3    . ALA A 1 195 ? -34.263 -19.085 -45.793 1.00 32.61  ? 195 ALA A HB3    1 
ATOM   3047  N N      . ASN A 1 196 ? -34.872 -16.506 -44.590 1.00 25.31  ? 196 ASN A N      1 
ATOM   3048  C CA     . ASN A 1 196 ? -35.835 -15.772 -43.786 1.00 24.38  ? 196 ASN A CA     1 
ATOM   3049  C C      . ASN A 1 196 ? -35.667 -14.272 -43.973 1.00 25.52  ? 196 ASN A C      1 
ATOM   3050  O O      . ASN A 1 196 ? -36.650 -13.552 -44.100 1.00 24.09  ? 196 ASN A O      1 
ATOM   3051  C CB     . ASN A 1 196 ? -35.693 -16.147 -42.304 1.00 27.92  ? 196 ASN A CB     1 
ATOM   3052  C CG     . ASN A 1 196 ? -36.867 -15.672 -41.466 1.00 29.01  ? 196 ASN A CG     1 
ATOM   3053  O OD1    . ASN A 1 196 ? -36.698 -14.913 -40.517 1.00 28.51  ? 196 ASN A OD1    1 
ATOM   3054  N ND2    . ASN A 1 196 ? -38.072 -16.105 -41.830 1.00 30.10  ? 196 ASN A ND2    1 
ATOM   3055  H H      . ASN A 1 196 ? -34.297 -16.951 -44.131 1.00 30.37  ? 196 ASN A H      1 
ATOM   3056  H HA     . ASN A 1 196 ? -36.730 -16.011 -44.072 1.00 29.26  ? 196 ASN A HA     1 
ATOM   3057  H HB2    . ASN A 1 196 ? -35.640 -17.112 -42.226 1.00 33.50  ? 196 ASN A HB2    1 
ATOM   3058  H HB3    . ASN A 1 196 ? -34.887 -15.740 -41.950 1.00 33.50  ? 196 ASN A HB3    1 
ATOM   3059  H HD21   . ASN A 1 196 ? -38.768 -15.861 -41.388 1.00 36.12  ? 196 ASN A HD21   1 
ATOM   3060  H HD22   . ASN A 1 196 ? -38.154 -16.629 -42.507 1.00 36.12  ? 196 ASN A HD22   1 
ATOM   3061  N N      . MET A 1 197 ? -34.425 -13.790 -43.987 1.00 22.65  ? 197 MET A N      1 
ATOM   3062  C CA     . MET A 1 197 ? -34.195 -12.358 -44.166 1.00 22.81  ? 197 MET A CA     1 
ATOM   3063  C C      . MET A 1 197 ? -34.737 -11.895 -45.513 1.00 23.31  ? 197 MET A C      1 
ATOM   3064  O O      . MET A 1 197 ? -35.285 -10.800 -45.627 1.00 28.10  ? 197 MET A O      1 
ATOM   3065  C CB     . MET A 1 197 ? -32.708 -12.026 -44.047 1.00 23.95  ? 197 MET A CB     1 
ATOM   3066  C CG     . MET A 1 197 ? -32.158 -12.237 -42.649 1.00 26.71  ? 197 MET A CG     1 
ATOM   3067  S SD     . MET A 1 197 ? -30.363 -12.113 -42.601 1.00 27.70  ? 197 MET A SD     1 
ATOM   3068  C CE     . MET A 1 197 ? -29.987 -13.150 -41.199 1.00 27.23  ? 197 MET A CE     1 
ATOM   3069  H H      . MET A 1 197 ? -33.711 -14.261 -43.897 1.00 27.18  ? 197 MET A H      1 
ATOM   3070  H HA     . MET A 1 197 ? -34.661 -11.879 -43.463 1.00 27.38  ? 197 MET A HA     1 
ATOM   3071  H HB2    . MET A 1 197 ? -32.209 -12.596 -44.653 1.00 28.74  ? 197 MET A HB2    1 
ATOM   3072  H HB3    . MET A 1 197 ? -32.574 -11.095 -44.284 1.00 28.74  ? 197 MET A HB3    1 
ATOM   3073  H HG2    . MET A 1 197 ? -32.523 -11.560 -42.058 1.00 32.05  ? 197 MET A HG2    1 
ATOM   3074  H HG3    . MET A 1 197 ? -32.408 -13.121 -42.339 1.00 32.05  ? 197 MET A HG3    1 
ATOM   3075  H HE1    . MET A 1 197 ? -29.025 -13.202 -41.092 1.00 32.67  ? 197 MET A HE1    1 
ATOM   3076  H HE2    . MET A 1 197 ? -30.389 -12.764 -40.405 1.00 32.67  ? 197 MET A HE2    1 
ATOM   3077  H HE3    . MET A 1 197 ? -30.350 -14.036 -41.357 1.00 32.67  ? 197 MET A HE3    1 
ATOM   3078  N N      . ARG A 1 198 ? -34.606 -12.745 -46.523 1.00 26.65  ? 198 ARG A N      1 
ATOM   3079  C CA     . ARG A 1 198 ? -35.091 -12.425 -47.864 1.00 28.57  ? 198 ARG A CA     1 
ATOM   3080  C C      . ARG A 1 198 ? -36.603 -12.321 -47.939 1.00 28.90  ? 198 ARG A C      1 
ATOM   3081  O O      . ARG A 1 198 ? -37.142 -11.391 -48.540 1.00 27.82  ? 198 ARG A O      1 
ATOM   3082  C CB     . ARG A 1 198 ? -34.639 -13.480 -48.859 1.00 30.84  ? 198 ARG A CB     1 
ATOM   3083  C CG     . ARG A 1 198 ? -33.204 -13.379 -49.252 1.00 32.03  ? 198 ARG A CG     1 
ATOM   3084  C CD     . ARG A 1 198 ? -32.856 -14.462 -50.249 1.00 37.01  ? 198 ARG A CD     1 
ATOM   3085  N NE     . ARG A 1 198 ? -31.423 -14.504 -50.516 1.00 36.74  ? 198 ARG A NE     1 
ATOM   3086  C CZ     . ARG A 1 198 ? -30.785 -15.548 -51.031 1.00 36.46  ? 198 ARG A CZ     1 
ATOM   3087  N NH1    . ARG A 1 198 ? -31.449 -16.658 -51.339 1.00 42.56  ? 198 ARG A NH1    1 
ATOM   3088  N NH2    . ARG A 1 198 ? -29.478 -15.486 -51.233 1.00 32.44  ? 198 ARG A NH2    1 
ATOM   3089  H H      . ARG A 1 198 ? -34.238 -13.520 -46.460 1.00 31.98  ? 198 ARG A H      1 
ATOM   3090  H HA     . ARG A 1 198 ? -34.718 -11.573 -48.139 1.00 34.28  ? 198 ARG A HA     1 
ATOM   3091  H HB2    . ARG A 1 198 ? -34.776 -14.356 -48.467 1.00 37.00  ? 198 ARG A HB2    1 
ATOM   3092  H HB3    . ARG A 1 198 ? -35.172 -13.395 -49.665 1.00 37.00  ? 198 ARG A HB3    1 
ATOM   3093  H HG2    . ARG A 1 198 ? -33.059 -12.521 -49.676 1.00 38.44  ? 198 ARG A HG2    1 
ATOM   3094  H HG3    . ARG A 1 198 ? -32.639 -13.478 -48.470 1.00 38.44  ? 198 ARG A HG3    1 
ATOM   3095  H HD2    . ARG A 1 198 ? -33.126 -15.321 -49.889 1.00 44.42  ? 198 ARG A HD2    1 
ATOM   3096  H HD3    . ARG A 1 198 ? -33.316 -14.288 -51.085 1.00 44.42  ? 198 ARG A HD3    1 
ATOM   3097  H HE     . ARG A 1 198 ? -30.945 -13.855 -50.217 1.00 44.09  ? 198 ARG A HE     1 
ATOM   3098  H HH11   . ARG A 1 198 ? -32.297 -16.707 -51.210 1.00 51.08  ? 198 ARG A HH11   1 
ATOM   3099  H HH12   . ARG A 1 198 ? -31.028 -17.330 -51.671 1.00 51.08  ? 198 ARG A HH12   1 
ATOM   3100  H HH21   . ARG A 1 198 ? -29.046 -14.770 -51.034 1.00 38.92  ? 198 ARG A HH21   1 
ATOM   3101  H HH22   . ARG A 1 198 ? -29.063 -16.161 -51.565 1.00 38.92  ? 198 ARG A HH22   1 
ATOM   3102  N N      . GLU A 1 199 ? -37.281 -13.308 -47.365 1.00 26.42  ? 199 GLU A N      1 
ATOM   3103  C CA     . GLU A 1 199 ? -38.735 -13.338 -47.383 1.00 31.44  ? 199 GLU A CA     1 
ATOM   3104  C C      . GLU A 1 199 ? -39.310 -12.130 -46.665 1.00 29.94  ? 199 GLU A C      1 
ATOM   3105  O O      . GLU A 1 199 ? -40.274 -11.520 -47.126 1.00 29.81  ? 199 GLU A O      1 
ATOM   3106  C CB     . GLU A 1 199 ? -39.262 -14.612 -46.731 1.00 35.68  ? 199 GLU A CB     1 
ATOM   3107  C CG     . GLU A 1 199 ? -39.281 -15.822 -47.622 1.00 45.60  ? 199 GLU A CG     1 
ATOM   3108  C CD     . GLU A 1 199 ? -40.215 -16.889 -47.086 1.00 61.19  ? 199 GLU A CD     1 
ATOM   3109  O OE1    . GLU A 1 199 ? -41.415 -16.866 -47.444 1.00 63.04  ? 199 GLU A OE1    1 
ATOM   3110  O OE2    . GLU A 1 199 ? -39.755 -17.733 -46.289 1.00 60.77  ? 199 GLU A OE2    1 
ATOM   3111  H H      . GLU A 1 199 ? -36.920 -13.974 -46.958 1.00 31.71  ? 199 GLU A H      1 
ATOM   3112  H HA     . GLU A 1 199 ? -39.043 -13.318 -48.303 1.00 37.72  ? 199 GLU A HA     1 
ATOM   3113  H HB2    . GLU A 1 199 ? -38.703 -14.821 -45.966 1.00 42.81  ? 199 GLU A HB2    1 
ATOM   3114  H HB3    . GLU A 1 199 ? -40.172 -14.453 -46.435 1.00 42.81  ? 199 GLU A HB3    1 
ATOM   3115  H HG2    . GLU A 1 199 ? -39.588 -15.565 -48.506 1.00 54.72  ? 199 GLU A HG2    1 
ATOM   3116  H HG3    . GLU A 1 199 ? -38.388 -16.197 -47.672 1.00 54.72  ? 199 GLU A HG3    1 
ATOM   3117  N N      . VAL A 1 200 ? -38.721 -11.792 -45.522 1.00 28.61  ? 200 VAL A N      1 
ATOM   3118  C CA     . VAL A 1 200 ? -39.152 -10.624 -44.773 1.00 27.24  ? 200 VAL A CA     1 
ATOM   3119  C C      . VAL A 1 200 ? -38.974 -9.354  -45.607 1.00 28.00  ? 200 VAL A C      1 
ATOM   3120  O O      . VAL A 1 200 ? -39.876 -8.510  -45.665 1.00 26.27  ? 200 VAL A O      1 
ATOM   3121  C CB     . VAL A 1 200 ? -38.381 -10.507 -43.437 1.00 30.36  ? 200 VAL A CB     1 
ATOM   3122  C CG1    . VAL A 1 200 ? -38.689 -9.187  -42.738 1.00 29.02  ? 200 VAL A CG1    1 
ATOM   3123  C CG2    . VAL A 1 200 ? -38.736 -11.677 -42.536 1.00 29.21  ? 200 VAL A CG2    1 
ATOM   3124  H H      . VAL A 1 200 ? -38.070 -12.224 -45.161 1.00 34.33  ? 200 VAL A H      1 
ATOM   3125  H HA     . VAL A 1 200 ? -40.095 -10.715 -44.566 1.00 32.69  ? 200 VAL A HA     1 
ATOM   3126  H HB     . VAL A 1 200 ? -37.428 -10.540 -43.615 1.00 36.43  ? 200 VAL A HB     1 
ATOM   3127  H HG11   . VAL A 1 200 ? -38.414 -9.252  -41.810 1.00 34.82  ? 200 VAL A HG11   1 
ATOM   3128  H HG12   . VAL A 1 200 ? -38.201 -8.472  -43.176 1.00 34.82  ? 200 VAL A HG12   1 
ATOM   3129  H HG13   . VAL A 1 200 ? -39.643 -9.019  -42.788 1.00 34.82  ? 200 VAL A HG13   1 
ATOM   3130  H HG21   . VAL A 1 200 ? -38.114 -11.701 -41.792 1.00 35.05  ? 200 VAL A HG21   1 
ATOM   3131  H HG22   . VAL A 1 200 ? -39.641 -11.558 -42.207 1.00 35.05  ? 200 VAL A HG22   1 
ATOM   3132  H HG23   . VAL A 1 200 ? -38.675 -12.501 -43.043 1.00 35.05  ? 200 VAL A HG23   1 
ATOM   3133  N N      . ARG A 1 201 ? -37.816 -9.216  -46.247 1.00 28.02  ? 201 ARG A N      1 
ATOM   3134  C CA     . ARG A 1 201 ? -37.536 -8.052  -47.090 1.00 28.31  ? 201 ARG A CA     1 
ATOM   3135  C C      . ARG A 1 201 ? -38.546 -7.964  -48.228 1.00 32.34  ? 201 ARG A C      1 
ATOM   3136  O O      . ARG A 1 201 ? -39.043 -6.887  -48.556 1.00 31.51  ? 201 ARG A O      1 
ATOM   3137  C CB     . ARG A 1 201 ? -36.117 -8.130  -47.664 1.00 32.53  ? 201 ARG A CB     1 
ATOM   3138  C CG     . ARG A 1 201 ? -35.755 -7.058  -48.712 1.00 41.49  ? 201 ARG A CG     1 
ATOM   3139  C CD     . ARG A 1 201 ? -35.350 -5.735  -48.077 1.00 40.15  ? 201 ARG A CD     1 
ATOM   3140  N NE     . ARG A 1 201 ? -36.492 -4.936  -47.651 1.00 41.23  ? 201 ARG A NE     1 
ATOM   3141  C CZ     . ARG A 1 201 ? -36.414 -3.885  -46.840 1.00 48.61  ? 201 ARG A CZ     1 
ATOM   3142  N NH1    . ARG A 1 201 ? -35.243 -3.508  -46.341 1.00 45.20  ? 201 ARG A NH1    1 
ATOM   3143  N NH2    . ARG A 1 201 ? -37.515 -3.216  -46.515 1.00 42.73  ? 201 ARG A NH2    1 
ATOM   3144  H H      . ARG A 1 201 ? -37.172 -9.784  -46.210 1.00 33.62  ? 201 ARG A H      1 
ATOM   3145  H HA     . ARG A 1 201 ? -37.606 -7.245  -46.557 1.00 33.97  ? 201 ARG A HA     1 
ATOM   3146  H HB2    . ARG A 1 201 ? -35.487 -8.046  -46.932 1.00 39.03  ? 201 ARG A HB2    1 
ATOM   3147  H HB3    . ARG A 1 201 ? -36.006 -8.996  -48.086 1.00 39.03  ? 201 ARG A HB3    1 
ATOM   3148  H HG2    . ARG A 1 201 ? -35.001 -7.377  -49.232 1.00 49.79  ? 201 ARG A HG2    1 
ATOM   3149  H HG3    . ARG A 1 201 ? -36.508 -6.891  -49.299 1.00 49.79  ? 201 ARG A HG3    1 
ATOM   3150  H HD2    . ARG A 1 201 ? -34.802 -5.914  -47.302 1.00 48.18  ? 201 ARG A HD2    1 
ATOM   3151  H HD3    . ARG A 1 201 ? -34.848 -5.216  -48.725 1.00 48.18  ? 201 ARG A HD3    1 
ATOM   3152  H HE     . ARG A 1 201 ? -37.269 -5.159  -47.944 1.00 49.47  ? 201 ARG A HE     1 
ATOM   3153  H HH11   . ARG A 1 201 ? -34.526 -3.935  -46.547 1.00 54.24  ? 201 ARG A HH11   1 
ATOM   3154  H HH12   . ARG A 1 201 ? -35.201 -2.829  -45.815 1.00 54.24  ? 201 ARG A HH12   1 
ATOM   3155  H HH21   . ARG A 1 201 ? -38.276 -3.460  -46.833 1.00 51.28  ? 201 ARG A HH21   1 
ATOM   3156  H HH22   . ARG A 1 201 ? -37.467 -2.540  -45.986 1.00 51.28  ? 201 ARG A HH22   1 
ATOM   3157  N N      . GLN A 1 202 ? -38.836 -9.111  -48.830 1.00 28.65  ? 202 GLN A N      1 
ATOM   3158  C CA     . GLN A 1 202 ? -39.728 -9.165  -49.985 1.00 35.65  ? 202 GLN A CA     1 
ATOM   3159  C C      . GLN A 1 202 ? -41.126 -8.679  -49.608 1.00 33.24  ? 202 GLN A C      1 
ATOM   3160  O O      . GLN A 1 202 ? -41.724 -7.859  -50.307 1.00 34.48  ? 202 GLN A O      1 
ATOM   3161  C CB     . GLN A 1 202 ? -39.780 -10.589 -50.533 1.00 36.51  ? 202 GLN A CB     1 
ATOM   3162  C CG     . GLN A 1 202 ? -40.361 -10.717 -51.928 1.00 50.56  ? 202 GLN A CG     1 
ATOM   3163  C CD     . GLN A 1 202 ? -40.410 -12.162 -52.397 1.00 58.00  ? 202 GLN A CD     1 
ATOM   3164  O OE1    . GLN A 1 202 ? -40.082 -13.082 -51.646 1.00 67.19  ? 202 GLN A OE1    1 
ATOM   3165  N NE2    . GLN A 1 202 ? -40.824 -12.367 -53.639 1.00 54.73  ? 202 GLN A NE2    1 
ATOM   3166  H H      . GLN A 1 202 ? -38.528 -9.877  -48.589 1.00 34.38  ? 202 GLN A H      1 
ATOM   3167  H HA     . GLN A 1 202 ? -39.383 -8.585  -50.682 1.00 42.78  ? 202 GLN A HA     1 
ATOM   3168  H HB2    . GLN A 1 202 ? -38.877 -10.943 -50.558 1.00 43.82  ? 202 GLN A HB2    1 
ATOM   3169  H HB3    . GLN A 1 202 ? -40.325 -11.128 -49.938 1.00 43.82  ? 202 GLN A HB3    1 
ATOM   3170  H HG2    . GLN A 1 202 ? -41.266 -10.368 -51.929 1.00 60.67  ? 202 GLN A HG2    1 
ATOM   3171  H HG3    . GLN A 1 202 ? -39.810 -10.216 -52.549 1.00 60.67  ? 202 GLN A HG3    1 
ATOM   3172  H HE21   . GLN A 1 202 ? -41.048 -11.700 -54.133 1.00 65.67  ? 202 GLN A HE21   1 
ATOM   3173  H HE22   . GLN A 1 202 ? -40.869 -13.167 -53.951 1.00 65.67  ? 202 GLN A HE22   1 
ATOM   3174  N N      . LEU A 1 203 ? -41.629 -9.179  -48.487 1.00 28.64  ? 203 LEU A N      1 
ATOM   3175  C CA     . LEU A 1 203 ? -42.952 -8.823  -48.007 1.00 34.04  ? 203 LEU A CA     1 
ATOM   3176  C C      . LEU A 1 203 ? -43.006 -7.364  -47.591 1.00 36.16  ? 203 LEU A C      1 
ATOM   3177  O O      . LEU A 1 203 ? -43.945 -6.639  -47.927 1.00 35.86  ? 203 LEU A O      1 
ATOM   3178  C CB     . LEU A 1 203 ? -43.343 -9.722  -46.833 1.00 36.31  ? 203 LEU A CB     1 
ATOM   3179  C CG     . LEU A 1 203 ? -44.702 -9.455  -46.187 1.00 41.17  ? 203 LEU A CG     1 
ATOM   3180  C CD1    . LEU A 1 203 ? -45.813 -9.522  -47.226 1.00 45.21  ? 203 LEU A CD1    1 
ATOM   3181  C CD2    . LEU A 1 203 ? -44.952 -10.453 -45.068 1.00 39.22  ? 203 LEU A CD2    1 
ATOM   3182  H H      . LEU A 1 203 ? -41.214 -9.736  -47.979 1.00 34.37  ? 203 LEU A H      1 
ATOM   3183  H HA     . LEU A 1 203 ? -43.594 -8.958  -48.721 1.00 40.85  ? 203 LEU A HA     1 
ATOM   3184  H HB2    . LEU A 1 203 ? -43.349 -10.641 -47.144 1.00 43.57  ? 203 LEU A HB2    1 
ATOM   3185  H HB3    . LEU A 1 203 ? -42.672 -9.623  -46.140 1.00 43.57  ? 203 LEU A HB3    1 
ATOM   3186  H HG     . LEU A 1 203 ? -44.703 -8.565  -45.801 1.00 49.40  ? 203 LEU A HG     1 
ATOM   3187  H HD11   . LEU A 1 203 ? -46.670 -9.473  -46.774 1.00 54.25  ? 203 LEU A HD11   1 
ATOM   3188  H HD12   . LEU A 1 203 ? -45.720 -8.776  -47.839 1.00 54.25  ? 203 LEU A HD12   1 
ATOM   3189  H HD13   . LEU A 1 203 ? -45.742 -10.360 -47.710 1.00 54.25  ? 203 LEU A HD13   1 
ATOM   3190  H HD21   . LEU A 1 203 ? -45.804 -10.252 -44.651 1.00 47.06  ? 203 LEU A HD21   1 
ATOM   3191  H HD22   . LEU A 1 203 ? -44.969 -11.348 -45.442 1.00 47.06  ? 203 LEU A HD22   1 
ATOM   3192  H HD23   . LEU A 1 203 ? -44.239 -10.380 -44.416 1.00 47.06  ? 203 LEU A HD23   1 
ATOM   3193  N N      . CYS A 1 204 ? -41.990 -6.929  -46.859 1.00 32.07  ? 204 CYS A N      1 
ATOM   3194  C CA     . CYS A 1 204 ? -41.966 -5.566  -46.370 1.00 31.26  ? 204 CYS A CA     1 
ATOM   3195  C C      . CYS A 1 204 ? -41.846 -4.570  -47.527 1.00 33.83  ? 204 CYS A C      1 
ATOM   3196  O O      . CYS A 1 204 ? -42.475 -3.511  -47.502 1.00 34.33  ? 204 CYS A O      1 
ATOM   3197  C CB     . CYS A 1 204 ? -40.827 -5.391  -45.367 1.00 33.15  ? 204 CYS A CB     1 
ATOM   3198  S SG     . CYS A 1 204 ? -41.245 -6.049  -43.740 1.00 31.50  ? 204 CYS A SG     1 
ATOM   3199  H H      . CYS A 1 204 ? -41.308 -7.402  -46.634 1.00 38.48  ? 204 CYS A H      1 
ATOM   3200  H HA     . CYS A 1 204 ? -42.799 -5.385  -45.907 1.00 37.51  ? 204 CYS A HA     1 
ATOM   3201  H HB2    . CYS A 1 204 ? -40.043 -5.861  -45.691 1.00 39.78  ? 204 CYS A HB2    1 
ATOM   3202  H HB3    . CYS A 1 204 ? -40.634 -4.448  -45.269 1.00 39.78  ? 204 CYS A HB3    1 
ATOM   3203  H HG     . CYS A 1 204 ? -40.315 -5.899  -42.999 1.00 37.80  ? 204 CYS A HG     1 
ATOM   3204  N N      . ASP A 1 205 ? -41.056 -4.914  -48.541 1.00 32.69  ? 205 ASP A N      1 
ATOM   3205  C CA     . ASP A 1 205 ? -40.933 -4.069  -49.731 1.00 36.42  ? 205 ASP A CA     1 
ATOM   3206  C C      . ASP A 1 205 ? -42.274 -3.885  -50.433 1.00 36.29  ? 205 ASP A C      1 
ATOM   3207  O O      . ASP A 1 205 ? -42.588 -2.793  -50.899 1.00 38.17  ? 205 ASP A O      1 
ATOM   3208  C CB     . ASP A 1 205 ? -39.932 -4.660  -50.723 1.00 32.59  ? 205 ASP A CB     1 
ATOM   3209  C CG     . ASP A 1 205 ? -38.488 -4.314  -50.387 1.00 40.35  ? 205 ASP A CG     1 
ATOM   3210  O OD1    . ASP A 1 205 ? -38.255 -3.450  -49.514 1.00 43.26  ? 205 ASP A OD1    1 
ATOM   3211  O OD2    . ASP A 1 205 ? -37.586 -4.907  -51.013 1.00 37.83  ? 205 ASP A OD2    1 
ATOM   3212  H H      . ASP A 1 205 ? -40.580 -5.630  -48.567 1.00 39.22  ? 205 ASP A H      1 
ATOM   3213  H HA     . ASP A 1 205 ? -40.626 -3.190  -49.464 1.00 43.70  ? 205 ASP A HA     1 
ATOM   3214  H HB2    . ASP A 1 205 ? -40.017 -5.626  -50.719 1.00 39.11  ? 205 ASP A HB2    1 
ATOM   3215  H HB3    . ASP A 1 205 ? -40.124 -4.314  -51.609 1.00 39.11  ? 205 ASP A HB3    1 
ATOM   3216  N N      . LYS A 1 206 ? -43.054 -4.956  -50.515 1.00 32.81  ? 206 LYS A N      1 
ATOM   3217  C CA     . LYS A 1 206 ? -44.379 -4.888  -51.126 1.00 39.44  ? 206 LYS A CA     1 
ATOM   3218  C C      . LYS A 1 206 ? -45.254 -3.821  -50.457 1.00 37.94  ? 206 LYS A C      1 
ATOM   3219  O O      . LYS A 1 206 ? -46.062 -3.172  -51.117 1.00 41.70  ? 206 LYS A O      1 
ATOM   3220  C CB     . LYS A 1 206 ? -45.070 -6.251  -51.050 1.00 43.79  ? 206 LYS A CB     1 
ATOM   3221  C CG     . LYS A 1 206 ? -45.784 -6.663  -52.326 1.00 61.24  ? 206 LYS A CG     1 
ATOM   3222  C CD     . LYS A 1 206 ? -46.867 -7.706  -52.061 1.00 56.78  ? 206 LYS A CD     1 
ATOM   3223  C CE     . LYS A 1 206 ? -46.307 -8.986  -51.457 1.00 66.34  ? 206 LYS A CE     1 
ATOM   3224  N NZ     . LYS A 1 206 ? -47.394 -9.919  -51.049 1.00 78.82  ? 206 LYS A NZ     1 
ATOM   3225  H H      . LYS A 1 206 ? -42.839 -5.736  -50.223 1.00 39.37  ? 206 LYS A H      1 
ATOM   3226  H HA     . LYS A 1 206 ? -44.283 -4.653  -52.062 1.00 47.33  ? 206 LYS A HA     1 
ATOM   3227  H HB2    . LYS A 1 206 ? -44.404 -6.929  -50.855 1.00 52.55  ? 206 LYS A HB2    1 
ATOM   3228  H HB3    . LYS A 1 206 ? -45.729 -6.226  -50.339 1.00 52.55  ? 206 LYS A HB3    1 
ATOM   3229  H HG2    . LYS A 1 206 ? -46.205 -5.884  -52.722 1.00 73.49  ? 206 LYS A HG2    1 
ATOM   3230  H HG3    . LYS A 1 206 ? -45.140 -7.045  -52.943 1.00 73.49  ? 206 LYS A HG3    1 
ATOM   3231  H HD2    . LYS A 1 206 ? -47.515 -7.339  -51.440 1.00 68.13  ? 206 LYS A HD2    1 
ATOM   3232  H HD3    . LYS A 1 206 ? -47.300 -7.933  -52.899 1.00 68.13  ? 206 LYS A HD3    1 
ATOM   3233  H HE2    . LYS A 1 206 ? -45.753 -9.434  -52.115 1.00 79.61  ? 206 LYS A HE2    1 
ATOM   3234  H HE3    . LYS A 1 206 ? -45.785 -8.773  -50.668 1.00 79.61  ? 206 LYS A HE3    1 
ATOM   3235  H HZ1    . LYS A 1 206 ? -47.044 -10.659 -50.699 1.00 94.58  ? 206 LYS A HZ1    1 
ATOM   3236  H HZ2    . LYS A 1 206 ? -47.916 -9.531  -50.442 1.00 94.58  ? 206 LYS A HZ2    1 
ATOM   3237  H HZ3    . LYS A 1 206 ? -47.887 -10.139 -51.756 1.00 94.58  ? 206 LYS A HZ3    1 
ATOM   3238  N N      . HIS A 1 207 ? -45.070 -3.630  -49.152 1.00 38.30  ? 207 HIS A N      1 
ATOM   3239  C CA     . HIS A 1 207 ? -45.910 -2.725  -48.369 1.00 35.06  ? 207 HIS A CA     1 
ATOM   3240  C C      . HIS A 1 207 ? -45.189 -1.451  -47.918 1.00 33.61  ? 207 HIS A C      1 
ATOM   3241  O O      . HIS A 1 207 ? -45.743 -0.650  -47.163 1.00 36.38  ? 207 HIS A O      1 
ATOM   3242  C CB     . HIS A 1 207 ? -46.453 -3.458  -47.138 1.00 36.37  ? 207 HIS A CB     1 
ATOM   3243  C CG     . HIS A 1 207 ? -47.399 -4.572  -47.464 1.00 40.73  ? 207 HIS A CG     1 
ATOM   3244  N ND1    . HIS A 1 207 ? -46.975 -5.858  -47.724 1.00 49.61  ? 207 HIS A ND1    1 
ATOM   3245  C CD2    . HIS A 1 207 ? -48.748 -4.592  -47.574 1.00 38.80  ? 207 HIS A CD2    1 
ATOM   3246  C CE1    . HIS A 1 207 ? -48.023 -6.622  -47.977 1.00 45.11  ? 207 HIS A CE1    1 
ATOM   3247  N NE2    . HIS A 1 207 ? -49.111 -5.879  -47.890 1.00 44.23  ? 207 HIS A NE2    1 
ATOM   3248  H H      . HIS A 1 207 ? -44.457 -4.018  -48.691 1.00 45.96  ? 207 HIS A H      1 
ATOM   3249  H HA     . HIS A 1 207 ? -46.673 -2.454  -48.902 1.00 42.07  ? 207 HIS A HA     1 
ATOM   3250  H HB2    . HIS A 1 207 ? -45.708 -3.837  -46.646 1.00 43.65  ? 207 HIS A HB2    1 
ATOM   3251  H HB3    . HIS A 1 207 ? -46.927 -2.824  -46.579 1.00 43.65  ? 207 HIS A HB3    1 
ATOM   3252  H HD1    . HIS A 1 207 ? -46.156 -6.122  -47.721 1.00 59.53  ? 207 HIS A HD1    1 
ATOM   3253  H HD2    . HIS A 1 207 ? -49.323 -3.874  -47.452 1.00 46.56  ? 207 HIS A HD2    1 
ATOM   3254  H HE1    . HIS A 1 207 ? -47.998 -7.529  -48.181 1.00 54.13  ? 207 HIS A HE1    1 
ATOM   3255  N N      . GLY A 1 208 ? -43.957 -1.268  -48.378 1.00 35.13  ? 208 GLY A N      1 
ATOM   3256  C CA     . GLY A 1 208 ? -43.181 -0.084  -48.054 1.00 32.35  ? 208 GLY A CA     1 
ATOM   3257  C C      . GLY A 1 208 ? -42.761 -0.015  -46.597 1.00 35.87  ? 208 GLY A C      1 
ATOM   3258  O O      . GLY A 1 208 ? -42.599 1.074   -46.043 1.00 35.78  ? 208 GLY A O      1 
ATOM   3259  H H      . GLY A 1 208 ? -43.543 -1.824  -48.887 1.00 42.15  ? 208 GLY A H      1 
ATOM   3260  H HA2    . GLY A 1 208 ? -42.381 -0.067  -48.602 1.00 38.82  ? 208 GLY A HA2    1 
ATOM   3261  H HA3    . GLY A 1 208 ? -43.705 0.707   -48.257 1.00 38.82  ? 208 GLY A HA3    1 
ATOM   3262  N N      . ILE A 1 209 ? -42.572 -1.178  -45.980 1.00 36.56  ? 209 ILE A N      1 
ATOM   3263  C CA     . ILE A 1 209 ? -42.222 -1.247  -44.564 1.00 36.10  ? 209 ILE A CA     1 
ATOM   3264  C C      . ILE A 1 209 ? -40.710 -1.341  -44.371 1.00 31.30  ? 209 ILE A C      1 
ATOM   3265  O O      . ILE A 1 209 ? -40.034 -2.111  -45.048 1.00 28.98  ? 209 ILE A O      1 
ATOM   3266  C CB     . ILE A 1 209 ? -42.901 -2.448  -43.881 1.00 35.29  ? 209 ILE A CB     1 
ATOM   3267  C CG1    . ILE A 1 209 ? -44.423 -2.351  -44.052 1.00 36.60  ? 209 ILE A CG1    1 
ATOM   3268  C CG2    . ILE A 1 209 ? -42.535 -2.496  -42.398 1.00 34.03  ? 209 ILE A CG2    1 
ATOM   3269  C CD1    . ILE A 1 209 ? -45.200 -3.550  -43.527 1.00 36.52  ? 209 ILE A CD1    1 
ATOM   3270  H H      . ILE A 1 209 ? -42.641 -1.946  -46.361 1.00 43.87  ? 209 ILE A H      1 
ATOM   3271  H HA     . ILE A 1 209 ? -42.530 -0.443  -44.117 1.00 43.32  ? 209 ILE A HA     1 
ATOM   3272  H HB     . ILE A 1 209 ? -42.591 -3.264  -44.305 1.00 42.35  ? 209 ILE A HB     1 
ATOM   3273  H HG12   . ILE A 1 209 ? -44.738 -1.566  -43.577 1.00 43.92  ? 209 ILE A HG12   1 
ATOM   3274  H HG13   . ILE A 1 209 ? -44.627 -2.264  -44.996 1.00 43.92  ? 209 ILE A HG13   1 
ATOM   3275  H HG21   . ILE A 1 209 ? -43.073 -3.172  -41.957 1.00 40.84  ? 209 ILE A HG21   1 
ATOM   3276  H HG22   . ILE A 1 209 ? -41.596 -2.719  -42.307 1.00 40.84  ? 209 ILE A HG22   1 
ATOM   3277  H HG23   . ILE A 1 209 ? -42.709 -1.627  -42.003 1.00 40.84  ? 209 ILE A HG23   1 
ATOM   3278  H HD11   . ILE A 1 209 ? -46.113 -3.500  -43.851 1.00 43.82  ? 209 ILE A HD11   1 
ATOM   3279  H HD12   . ILE A 1 209 ? -44.779 -4.363  -43.848 1.00 43.82  ? 209 ILE A HD12   1 
ATOM   3280  H HD13   . ILE A 1 209 ? -45.192 -3.534  -42.557 1.00 43.82  ? 209 ILE A HD13   1 
ATOM   3281  N N      . LYS A 1 210 ? -40.195 -0.552  -43.433 1.00 30.31  ? 210 LYS A N      1 
ATOM   3282  C CA     . LYS A 1 210 ? -38.771 -0.548  -43.117 1.00 34.47  ? 210 LYS A CA     1 
ATOM   3283  C C      . LYS A 1 210 ? -38.370 -1.732  -42.243 1.00 31.75  ? 210 LYS A C      1 
ATOM   3284  O O      . LYS A 1 210 ? -39.133 -2.167  -41.380 1.00 27.82  ? 210 LYS A O      1 
ATOM   3285  C CB     . LYS A 1 210 ? -38.386 0.760   -42.417 1.00 35.37  ? 210 LYS A CB     1 
ATOM   3286  C CG     . LYS A 1 210 ? -38.550 2.011   -43.277 1.00 37.89  ? 210 LYS A CG     1 
ATOM   3287  C CD     . LYS A 1 210 ? -37.628 1.986   -44.491 1.00 44.86  ? 210 LYS A CD     1 
ATOM   3288  C CE     . LYS A 1 210 ? -37.904 3.145   -45.430 1.00 59.71  ? 210 LYS A CE     1 
ATOM   3289  N NZ     . LYS A 1 210 ? -37.216 2.957   -46.737 1.00 69.02  ? 210 LYS A NZ     1 
ATOM   3290  H H      . LYS A 1 210 ? -40.657 -0.002  -42.959 1.00 36.38  ? 210 LYS A H      1 
ATOM   3291  H HA     . LYS A 1 210 ? -38.269 -0.613  -43.942 1.00 41.36  ? 210 LYS A HA     1 
ATOM   3292  H HB2    . LYS A 1 210 ? -38.945 0.868   -41.632 1.00 42.45  ? 210 LYS A HB2    1 
ATOM   3293  H HB3    . LYS A 1 210 ? -37.455 0.707   -42.150 1.00 42.45  ? 210 LYS A HB3    1 
ATOM   3294  H HG2    . LYS A 1 210 ? -39.466 2.064   -43.593 1.00 45.47  ? 210 LYS A HG2    1 
ATOM   3295  H HG3    . LYS A 1 210 ? -38.332 2.794   -42.747 1.00 45.47  ? 210 LYS A HG3    1 
ATOM   3296  H HD2    . LYS A 1 210 ? -36.707 2.049   -44.194 1.00 53.83  ? 210 LYS A HD2    1 
ATOM   3297  H HD3    . LYS A 1 210 ? -37.764 1.166   -44.989 1.00 53.83  ? 210 LYS A HD3    1 
ATOM   3298  H HE2    . LYS A 1 210 ? -38.858 3.205   -45.594 1.00 71.65  ? 210 LYS A HE2    1 
ATOM   3299  H HE3    . LYS A 1 210 ? -37.579 3.967   -45.030 1.00 71.65  ? 210 LYS A HE3    1 
ATOM   3300  H HZ1    . LYS A 1 210 ? -37.389 3.646   -47.274 1.00 82.83  ? 210 LYS A HZ1    1 
ATOM   3301  H HZ2    . LYS A 1 210 ? -36.337 2.902   -46.612 1.00 82.83  ? 210 LYS A HZ2    1 
ATOM   3302  H HZ3    . LYS A 1 210 ? -37.501 2.209   -47.126 1.00 82.83  ? 210 LYS A HZ3    1 
ATOM   3303  N N      . VAL A 1 211 ? -37.166 -2.242  -42.488 1.00 30.83  ? 211 VAL A N      1 
ATOM   3304  C CA     . VAL A 1 211 ? -36.573 -3.300  -41.673 1.00 30.58  ? 211 VAL A CA     1 
ATOM   3305  C C      . VAL A 1 211 ? -35.237 -2.824  -41.091 1.00 27.03  ? 211 VAL A C      1 
ATOM   3306  O O      . VAL A 1 211 ? -34.324 -2.453  -41.828 1.00 25.94  ? 211 VAL A O      1 
ATOM   3307  C CB     . VAL A 1 211 ? -36.356 -4.595  -42.497 1.00 29.05  ? 211 VAL A CB     1 
ATOM   3308  C CG1    . VAL A 1 211 ? -35.755 -5.710  -41.637 1.00 30.55  ? 211 VAL A CG1    1 
ATOM   3309  C CG2    . VAL A 1 211 ? -37.675 -5.061  -43.114 1.00 31.37  ? 211 VAL A CG2    1 
ATOM   3310  H H      . VAL A 1 211 ? -36.662 -1.986  -43.136 1.00 36.99  ? 211 VAL A H      1 
ATOM   3311  H HA     . VAL A 1 211 ? -37.161 -3.512  -40.932 1.00 36.70  ? 211 VAL A HA     1 
ATOM   3312  H HB     . VAL A 1 211 ? -35.737 -4.408  -43.220 1.00 34.86  ? 211 VAL A HB     1 
ATOM   3313  H HG11   . VAL A 1 211 ? -35.786 -6.542  -42.135 1.00 36.66  ? 211 VAL A HG11   1 
ATOM   3314  H HG12   . VAL A 1 211 ? -34.835 -5.487  -41.424 1.00 36.66  ? 211 VAL A HG12   1 
ATOM   3315  H HG13   . VAL A 1 211 ? -36.274 -5.794  -40.822 1.00 36.66  ? 211 VAL A HG13   1 
ATOM   3316  H HG21   . VAL A 1 211 ? -37.530 -5.904  -43.571 1.00 37.64  ? 211 VAL A HG21   1 
ATOM   3317  H HG22   . VAL A 1 211 ? -38.326 -5.175  -42.404 1.00 37.64  ? 211 VAL A HG22   1 
ATOM   3318  H HG23   . VAL A 1 211 ? -37.985 -4.391  -43.744 1.00 37.64  ? 211 VAL A HG23   1 
ATOM   3319  N N      . PHE A 1 212 ? -35.142 -2.818  -39.767 1.00 24.64  ? 212 PHE A N      1 
ATOM   3320  C CA     . PHE A 1 212 ? -33.875 -2.546  -39.091 1.00 25.34  ? 212 PHE A CA     1 
ATOM   3321  C C      . PHE A 1 212 ? -33.424 -3.744  -38.266 1.00 27.31  ? 212 PHE A C      1 
ATOM   3322  O O      . PHE A 1 212 ? -34.207 -4.318  -37.509 1.00 27.63  ? 212 PHE A O      1 
ATOM   3323  C CB     . PHE A 1 212 ? -34.002 -1.319  -38.198 1.00 24.90  ? 212 PHE A CB     1 
ATOM   3324  C CG     . PHE A 1 212 ? -34.330 -0.065  -38.952 1.00 29.40  ? 212 PHE A CG     1 
ATOM   3325  C CD1    . PHE A 1 212 ? -33.337 0.641   -39.608 1.00 31.26  ? 212 PHE A CD1    1 
ATOM   3326  C CD2    . PHE A 1 212 ? -35.631 0.400   -39.016 1.00 31.53  ? 212 PHE A CD2    1 
ATOM   3327  C CE1    . PHE A 1 212 ? -33.632 1.791   -40.309 1.00 31.75  ? 212 PHE A CE1    1 
ATOM   3328  C CE2    . PHE A 1 212 ? -35.932 1.553   -39.716 1.00 34.23  ? 212 PHE A CE2    1 
ATOM   3329  C CZ     . PHE A 1 212 ? -34.929 2.247   -40.366 1.00 32.37  ? 212 PHE A CZ     1 
ATOM   3330  H H      . PHE A 1 212 ? -35.799 -2.969  -39.233 1.00 29.57  ? 212 PHE A H      1 
ATOM   3331  H HA     . PHE A 1 212 ? -33.183 -2.364  -39.745 1.00 30.40  ? 212 PHE A HA     1 
ATOM   3332  H HB2    . PHE A 1 212 ? -34.710 -1.472  -37.553 1.00 29.88  ? 212 PHE A HB2    1 
ATOM   3333  H HB3    . PHE A 1 212 ? -33.160 -1.178  -37.737 1.00 29.88  ? 212 PHE A HB3    1 
ATOM   3334  H HD1    . PHE A 1 212 ? -32.459 0.336   -39.575 1.00 37.52  ? 212 PHE A HD1    1 
ATOM   3335  H HD2    . PHE A 1 212 ? -36.309 -0.066  -38.581 1.00 37.83  ? 212 PHE A HD2    1 
ATOM   3336  H HE1    . PHE A 1 212 ? -32.955 2.257   -40.744 1.00 38.09  ? 212 PHE A HE1    1 
ATOM   3337  H HE2    . PHE A 1 212 ? -36.809 1.860   -39.753 1.00 41.08  ? 212 PHE A HE2    1 
ATOM   3338  H HZ     . PHE A 1 212 ? -35.129 3.024   -40.836 1.00 38.85  ? 212 PHE A HZ     1 
ATOM   3339  N N      . TYR A 1 213 ? -32.153 -4.104  -38.408 1.00 22.68  ? 213 TYR A N      1 
ATOM   3340  C CA     . TYR A 1 213 ? -31.592 -5.233  -37.679 1.00 21.67  ? 213 TYR A CA     1 
ATOM   3341  C C      . TYR A 1 213 ? -31.066 -4.827  -36.304 1.00 27.07  ? 213 TYR A C      1 
ATOM   3342  O O      . TYR A 1 213 ? -30.396 -3.806  -36.156 1.00 24.39  ? 213 TYR A O      1 
ATOM   3343  C CB     . TYR A 1 213 ? -30.446 -5.884  -38.461 1.00 25.21  ? 213 TYR A CB     1 
ATOM   3344  C CG     . TYR A 1 213 ? -30.844 -6.704  -39.667 1.00 24.19  ? 213 TYR A CG     1 
ATOM   3345  C CD1    . TYR A 1 213 ? -32.148 -6.717  -40.138 1.00 24.62  ? 213 TYR A CD1    1 
ATOM   3346  C CD2    . TYR A 1 213 ? -29.905 -7.479  -40.327 1.00 23.69  ? 213 TYR A CD2    1 
ATOM   3347  C CE1    . TYR A 1 213 ? -32.498 -7.469  -41.237 1.00 24.49  ? 213 TYR A CE1    1 
ATOM   3348  C CE2    . TYR A 1 213 ? -30.245 -8.236  -41.425 1.00 25.56  ? 213 TYR A CE2    1 
ATOM   3349  C CZ     . TYR A 1 213 ? -31.541 -8.227  -41.879 1.00 29.38  ? 213 TYR A CZ     1 
ATOM   3350  O OH     . TYR A 1 213 ? -31.873 -8.985  -42.977 1.00 30.82  ? 213 TYR A OH     1 
ATOM   3351  H H      . TYR A 1 213 ? -31.591 -3.707  -38.924 1.00 27.21  ? 213 TYR A H      1 
ATOM   3352  H HA     . TYR A 1 213 ? -32.287 -5.892  -37.554 1.00 26.01  ? 213 TYR A HA     1 
ATOM   3353  H HB2    . TYR A 1 213 ? -29.853 -5.183  -38.772 1.00 30.25  ? 213 TYR A HB2    1 
ATOM   3354  H HB3    . TYR A 1 213 ? -29.962 -6.471  -37.860 1.00 30.25  ? 213 TYR A HB3    1 
ATOM   3355  H HD1    . TYR A 1 213 ? -32.796 -6.205  -39.711 1.00 29.55  ? 213 TYR A HD1    1 
ATOM   3356  H HD2    . TYR A 1 213 ? -29.026 -7.485  -40.024 1.00 28.43  ? 213 TYR A HD2    1 
ATOM   3357  H HE1    . TYR A 1 213 ? -33.375 -7.466  -41.545 1.00 29.39  ? 213 TYR A HE1    1 
ATOM   3358  H HE2    . TYR A 1 213 ? -29.601 -8.747  -41.859 1.00 30.67  ? 213 TYR A HE2    1 
ATOM   3359  H HH     . TYR A 1 213 ? -31.195 -9.391  -43.262 1.00 36.98  ? 213 TYR A HH     1 
ATOM   3360  N N      . ASP A 1 214 ? -31.374 -5.645  -35.306 1.00 23.79  ? 214 ASP A N      1 
ATOM   3361  C CA     . ASP A 1 214 ? -30.674 -5.620  -34.026 1.00 26.22  ? 214 ASP A CA     1 
ATOM   3362  C C      . ASP A 1 214 ? -29.551 -6.646  -34.156 1.00 27.81  ? 214 ASP A C      1 
ATOM   3363  O O      . ASP A 1 214 ? -29.753 -7.827  -33.895 1.00 23.32  ? 214 ASP A O      1 
ATOM   3364  C CB     . ASP A 1 214 ? -31.631 -5.952  -32.882 1.00 32.05  ? 214 ASP A CB     1 
ATOM   3365  C CG     . ASP A 1 214 ? -30.963 -5.924  -31.521 1.00 40.07  ? 214 ASP A CG     1 
ATOM   3366  O OD1    . ASP A 1 214 ? -29.717 -5.835  -31.454 1.00 35.29  ? 214 ASP A OD1    1 
ATOM   3367  O OD2    . ASP A 1 214 ? -31.700 -6.005  -30.511 1.00 37.43  ? 214 ASP A OD2    1 
ATOM   3368  H H      . ASP A 1 214 ? -31.997 -6.236  -35.346 1.00 28.55  ? 214 ASP A H      1 
ATOM   3369  H HA     . ASP A 1 214 ? -30.287 -4.745  -33.868 1.00 31.47  ? 214 ASP A HA     1 
ATOM   3370  H HB2    . ASP A 1 214 ? -32.350 -5.301  -32.875 1.00 38.46  ? 214 ASP A HB2    1 
ATOM   3371  H HB3    . ASP A 1 214 ? -31.992 -6.842  -33.020 1.00 38.46  ? 214 ASP A HB3    1 
ATOM   3372  N N      . ALA A 1 215 ? -28.376 -6.185  -34.580 1.00 25.79  ? 215 ALA A N      1 
ATOM   3373  C CA     . ALA A 1 215 ? -27.356 -7.068  -35.147 1.00 28.51  ? 215 ALA A CA     1 
ATOM   3374  C C      . ALA A 1 215 ? -26.198 -7.425  -34.220 1.00 22.28  ? 215 ALA A C      1 
ATOM   3375  O O      . ALA A 1 215 ? -25.101 -7.726  -34.694 1.00 24.82  ? 215 ALA A O      1 
ATOM   3376  C CB     . ALA A 1 215 ? -26.795 -6.427  -36.405 1.00 28.23  ? 215 ALA A CB     1 
ATOM   3377  H H      . ALA A 1 215 ? -28.143 -5.358  -34.550 1.00 30.95  ? 215 ALA A H      1 
ATOM   3378  H HA     . ALA A 1 215 ? -27.779 -7.899  -35.412 1.00 34.22  ? 215 ALA A HA     1 
ATOM   3379  H HB1    . ALA A 1 215 ? -26.180 -7.043  -36.831 1.00 33.88  ? 215 ALA A HB1    1 
ATOM   3380  H HB2    . ALA A 1 215 ? -27.528 -6.226  -37.007 1.00 33.88  ? 215 ALA A HB2    1 
ATOM   3381  H HB3    . ALA A 1 215 ? -26.334 -5.609  -36.163 1.00 33.88  ? 215 ALA A HB3    1 
ATOM   3382  N N      . THR A 1 216 ? -26.431 -7.431  -32.915 1.00 22.93  ? 216 THR A N      1 
ATOM   3383  C CA     . THR A 1 216 ? -25.325 -7.535  -31.962 1.00 23.31  ? 216 THR A CA     1 
ATOM   3384  C C      . THR A 1 216 ? -24.484 -8.799  -32.112 1.00 20.26  ? 216 THR A C      1 
ATOM   3385  O O      . THR A 1 216 ? -23.286 -8.775  -31.837 1.00 24.15  ? 216 THR A O      1 
ATOM   3386  C CB     . THR A 1 216 ? -25.827 -7.468  -30.509 1.00 26.24  ? 216 THR A CB     1 
ATOM   3387  O OG1    . THR A 1 216 ? -26.583 -8.641  -30.199 1.00 27.98  ? 216 THR A OG1    1 
ATOM   3388  C CG2    . THR A 1 216 ? -26.674 -6.233  -30.295 1.00 28.72  ? 216 THR A CG2    1 
ATOM   3389  H H      . THR A 1 216 ? -27.211 -7.381  -32.557 1.00 27.52  ? 216 THR A H      1 
ATOM   3390  H HA     . THR A 1 216 ? -24.734 -6.778  -32.099 1.00 27.98  ? 216 THR A HA     1 
ATOM   3391  H HB     . THR A 1 216 ? -25.064 -7.416  -29.912 1.00 31.49  ? 216 THR A HB     1 
ATOM   3392  H HG1    . THR A 1 216 ? -26.849 -8.609  -29.403 1.00 33.58  ? 216 THR A HG1    1 
ATOM   3393  H HG21   . THR A 1 216 ? -26.940 -6.169  -29.365 1.00 34.47  ? 216 THR A HG21   1 
ATOM   3394  H HG22   . THR A 1 216 ? -26.169 -5.440  -30.533 1.00 34.47  ? 216 THR A HG22   1 
ATOM   3395  H HG23   . THR A 1 216 ? -27.466 -6.278  -30.847 1.00 34.47  ? 216 THR A HG23   1 
ATOM   3396  N N      . ARG A 1 217 ? -25.090 -9.899  -32.545 1.00 19.39  ? 217 ARG A N      1 
ATOM   3397  C CA     . ARG A 1 217 ? -24.328 -11.132 -32.764 1.00 20.39  ? 217 ARG A CA     1 
ATOM   3398  C C      . ARG A 1 217 ? -24.492 -11.627 -34.198 1.00 22.27  ? 217 ARG A C      1 
ATOM   3399  O O      . ARG A 1 217 ? -24.716 -12.815 -34.455 1.00 19.08  ? 217 ARG A O      1 
ATOM   3400  C CB     . ARG A 1 217 ? -24.749 -12.196 -31.751 1.00 21.58  ? 217 ARG A CB     1 
ATOM   3401  C CG     . ARG A 1 217 ? -24.420 -11.778 -30.315 1.00 22.23  ? 217 ARG A CG     1 
ATOM   3402  C CD     . ARG A 1 217 ? -24.847 -12.809 -29.308 1.00 21.28  ? 217 ARG A CD     1 
ATOM   3403  N NE     . ARG A 1 217 ? -24.689 -12.342 -27.928 1.00 21.73  ? 217 ARG A NE     1 
ATOM   3404  C CZ     . ARG A 1 217 ? -25.629 -11.708 -27.239 1.00 24.35  ? 217 ARG A CZ     1 
ATOM   3405  N NH1    . ARG A 1 217 ? -26.813 -11.453 -27.793 1.00 24.31  ? 217 ARG A NH1    1 
ATOM   3406  N NH2    . ARG A 1 217 ? -25.387 -11.328 -25.988 1.00 23.17  ? 217 ARG A NH2    1 
ATOM   3407  H H      . ARG A 1 217 ? -25.930 -9.962  -32.719 1.00 23.26  ? 217 ARG A H      1 
ATOM   3408  H HA     . ARG A 1 217 ? -23.388 -10.960 -32.622 1.00 24.47  ? 217 ARG A HA     1 
ATOM   3409  H HB2    . ARG A 1 217 ? -25.706 -12.335 -31.813 1.00 25.90  ? 217 ARG A HB2    1 
ATOM   3410  H HB3    . ARG A 1 217 ? -24.278 -13.022 -31.940 1.00 25.90  ? 217 ARG A HB3    1 
ATOM   3411  H HG2    . ARG A 1 217 ? -23.461 -11.655 -30.232 1.00 26.67  ? 217 ARG A HG2    1 
ATOM   3412  H HG3    . ARG A 1 217 ? -24.881 -10.949 -30.112 1.00 26.67  ? 217 ARG A HG3    1 
ATOM   3413  H HD2    . ARG A 1 217 ? -25.776 -13.040 -29.458 1.00 25.53  ? 217 ARG A HD2    1 
ATOM   3414  H HD3    . ARG A 1 217 ? -24.293 -13.597 -29.415 1.00 25.53  ? 217 ARG A HD3    1 
ATOM   3415  H HE     . ARG A 1 217 ? -23.936 -12.489 -27.539 1.00 26.08  ? 217 ARG A HE     1 
ATOM   3416  H HH11   . ARG A 1 217 ? -26.979 -11.695 -28.600 1.00 29.18  ? 217 ARG A HH11   1 
ATOM   3417  H HH12   . ARG A 1 217 ? -27.416 -11.041 -27.339 1.00 29.18  ? 217 ARG A HH12   1 
ATOM   3418  H HH21   . ARG A 1 217 ? -24.623 -11.492 -25.629 1.00 27.81  ? 217 ARG A HH21   1 
ATOM   3419  H HH22   . ARG A 1 217 ? -25.994 -10.916 -25.539 1.00 27.81  ? 217 ARG A HH22   1 
ATOM   3420  N N      . CYS A 1 218 ? -24.341 -10.695 -35.130 1.00 19.39  ? 218 CYS A N      1 
ATOM   3421  C CA     . CYS A 1 218 ? -24.524 -10.980 -36.548 1.00 21.40  ? 218 CYS A CA     1 
ATOM   3422  C C      . CYS A 1 218 ? -23.434 -11.883 -37.114 1.00 20.61  ? 218 CYS A C      1 
ATOM   3423  O O      . CYS A 1 218 ? -23.670 -12.620 -38.073 1.00 19.56  ? 218 CYS A O      1 
ATOM   3424  C CB     . CYS A 1 218 ? -24.582 -9.676  -37.339 1.00 21.14  ? 218 CYS A CB     1 
ATOM   3425  S SG     . CYS A 1 218 ? -23.098 -8.617  -37.224 1.00 22.21  ? 218 CYS A SG     1 
ATOM   3426  H H      . CYS A 1 218 ? -24.130 -9.878  -34.965 1.00 23.27  ? 218 CYS A H      1 
ATOM   3427  H HA     . CYS A 1 218 ? -25.373 -11.434 -36.666 1.00 25.69  ? 218 CYS A HA     1 
ATOM   3428  H HB2    . CYS A 1 218 ? -24.713 -9.891  -38.276 1.00 25.37  ? 218 CYS A HB2    1 
ATOM   3429  H HB3    . CYS A 1 218 ? -25.336 -9.157  -37.018 1.00 25.37  ? 218 CYS A HB3    1 
ATOM   3430  H HG     . CYS A 1 218 ? -23.266 -7.630  -37.886 1.00 26.65  ? 218 CYS A HG     1 
ATOM   3431  N N      . VAL A 1 219 ? -22.242 -11.853 -36.527 1.00 18.36  ? 219 VAL A N      1 
ATOM   3432  C CA     . VAL A 1 219 ? -21.170 -12.708 -37.024 1.00 17.17  ? 219 VAL A CA     1 
ATOM   3433  C C      . VAL A 1 219 ? -21.386 -14.151 -36.558 1.00 20.60  ? 219 VAL A C      1 
ATOM   3434  O O      . VAL A 1 219 ? -21.172 -15.093 -37.325 1.00 18.61  ? 219 VAL A O      1 
ATOM   3435  C CB     . VAL A 1 219 ? -19.784 -12.211 -36.579 1.00 21.27  ? 219 VAL A CB     1 
ATOM   3436  C CG1    . VAL A 1 219 ? -18.698 -13.017 -37.268 1.00 22.50  ? 219 VAL A CG1    1 
ATOM   3437  C CG2    . VAL A 1 219 ? -19.629 -10.720 -36.915 1.00 20.64  ? 219 VAL A CG2    1 
ATOM   3438  H H      . VAL A 1 219 ? -22.031 -11.359 -35.855 1.00 22.03  ? 219 VAL A H      1 
ATOM   3439  H HA     . VAL A 1 219 ? -21.185 -12.703 -37.994 1.00 20.61  ? 219 VAL A HA     1 
ATOM   3440  H HB     . VAL A 1 219 ? -19.691 -12.323 -35.620 1.00 25.53  ? 219 VAL A HB     1 
ATOM   3441  H HG11   . VAL A 1 219 ? -17.843 -12.595 -37.095 1.00 27.00  ? 219 VAL A HG11   1 
ATOM   3442  H HG12   . VAL A 1 219 ? -18.698 -13.919 -36.914 1.00 27.00  ? 219 VAL A HG12   1 
ATOM   3443  H HG13   . VAL A 1 219 ? -18.873 -13.033 -38.222 1.00 27.00  ? 219 VAL A HG13   1 
ATOM   3444  H HG21   . VAL A 1 219 ? -18.716 -10.448 -36.730 1.00 24.77  ? 219 VAL A HG21   1 
ATOM   3445  H HG22   . VAL A 1 219 ? -19.830 -10.586 -37.855 1.00 24.77  ? 219 VAL A HG22   1 
ATOM   3446  H HG23   . VAL A 1 219 ? -20.244 -10.206 -36.369 1.00 24.77  ? 219 VAL A HG23   1 
ATOM   3447  N N      . GLU A 1 220 ? -21.807 -14.330 -35.307 1.00 18.86  ? 220 GLU A N      1 
ATOM   3448  C CA     . GLU A 1 220 ? -22.216 -15.652 -34.850 1.00 18.22  ? 220 GLU A CA     1 
ATOM   3449  C C      . GLU A 1 220 ? -23.312 -16.160 -35.783 1.00 16.44  ? 220 GLU A C      1 
ATOM   3450  O O      . GLU A 1 220 ? -23.271 -17.295 -36.244 1.00 17.36  ? 220 GLU A O      1 
ATOM   3451  C CB     . GLU A 1 220 ? -22.701 -15.612 -33.398 1.00 19.15  ? 220 GLU A CB     1 
ATOM   3452  C CG     . GLU A 1 220 ? -21.576 -15.399 -32.386 1.00 22.35  ? 220 GLU A CG     1 
ATOM   3453  C CD     . GLU A 1 220 ? -22.080 -15.151 -30.975 1.00 27.69  ? 220 GLU A CD     1 
ATOM   3454  O OE1    . GLU A 1 220 ? -21.298 -14.621 -30.154 1.00 21.71  ? 220 GLU A OE1    1 
ATOM   3455  O OE2    . GLU A 1 220 ? -23.253 -15.486 -30.688 1.00 23.32  ? 220 GLU A OE2    1 
ATOM   3456  H H      . GLU A 1 220 ? -21.864 -13.711 -34.713 1.00 22.63  ? 220 GLU A H      1 
ATOM   3457  H HA     . GLU A 1 220 ? -21.462 -16.259 -34.904 1.00 21.87  ? 220 GLU A HA     1 
ATOM   3458  H HB2    . GLU A 1 220 ? -23.333 -14.883 -33.298 1.00 22.98  ? 220 GLU A HB2    1 
ATOM   3459  H HB3    . GLU A 1 220 ? -23.134 -16.454 -33.189 1.00 22.98  ? 220 GLU A HB3    1 
ATOM   3460  H HG2    . GLU A 1 220 ? -21.015 -16.190 -32.368 1.00 26.82  ? 220 GLU A HG2    1 
ATOM   3461  H HG3    . GLU A 1 220 ? -21.052 -14.628 -32.656 1.00 26.82  ? 220 GLU A HG3    1 
ATOM   3462  N N      . ASN A 1 221 ? -24.263 -15.292 -36.104 1.00 19.99  ? 221 ASN A N      1 
ATOM   3463  C CA     . ASN A 1 221 ? -25.338 -15.674 -37.008 1.00 20.78  ? 221 ASN A CA     1 
ATOM   3464  C C      . ASN A 1 221 ? -24.805 -16.108 -38.373 1.00 20.73  ? 221 ASN A C      1 
ATOM   3465  O O      . ASN A 1 221 ? -25.256 -17.100 -38.935 1.00 19.71  ? 221 ASN A O      1 
ATOM   3466  C CB     . ASN A 1 221 ? -26.313 -14.521 -37.171 1.00 19.13  ? 221 ASN A CB     1 
ATOM   3467  C CG     . ASN A 1 221 ? -27.652 -14.969 -37.717 1.00 26.09  ? 221 ASN A CG     1 
ATOM   3468  O OD1    . ASN A 1 221 ? -28.537 -15.354 -36.958 1.00 21.39  ? 221 ASN A OD1    1 
ATOM   3469  N ND2    . ASN A 1 221 ? -27.809 -14.916 -39.039 1.00 21.09  ? 221 ASN A ND2    1 
ATOM   3470  H H      . ASN A 1 221 ? -24.309 -14.483 -35.815 1.00 23.99  ? 221 ASN A H      1 
ATOM   3471  H HA     . ASN A 1 221 ? -25.821 -16.422 -36.624 1.00 24.94  ? 221 ASN A HA     1 
ATOM   3472  H HB2    . ASN A 1 221 ? -26.463 -14.108 -36.306 1.00 22.95  ? 221 ASN A HB2    1 
ATOM   3473  H HB3    . ASN A 1 221 ? -25.938 -13.874 -37.788 1.00 22.95  ? 221 ASN A HB3    1 
ATOM   3474  H HD21   . ASN A 1 221 ? -28.553 -15.161 -39.394 1.00 25.30  ? 221 ASN A HD21   1 
ATOM   3475  H HD22   . ASN A 1 221 ? -27.166 -14.637 -39.538 1.00 25.30  ? 221 ASN A HD22   1 
ATOM   3476  N N      . ALA A 1 222 ? -23.834 -15.367 -38.894 1.00 19.45  ? 222 ALA A N      1 
ATOM   3477  C CA     . ALA A 1 222 ? -23.257 -15.663 -40.202 1.00 21.11  ? 222 ALA A CA     1 
ATOM   3478  C C      . ALA A 1 222 ? -22.600 -17.036 -40.198 1.00 19.98  ? 222 ALA A C      1 
ATOM   3479  O O      . ALA A 1 222 ? -22.701 -17.790 -41.179 1.00 18.25  ? 222 ALA A O      1 
ATOM   3480  C CB     . ALA A 1 222 ? -22.255 -14.585 -40.596 1.00 20.00  ? 222 ALA A CB     1 
ATOM   3481  H H      . ALA A 1 222 ? -23.488 -14.681 -38.507 1.00 23.34  ? 222 ALA A H      1 
ATOM   3482  H HA     . ALA A 1 222 ? -23.965 -15.671 -40.865 1.00 25.34  ? 222 ALA A HA     1 
ATOM   3483  H HB1    . ALA A 1 222 ? -21.885 -14.801 -41.466 1.00 24.00  ? 222 ALA A HB1    1 
ATOM   3484  H HB2    . ALA A 1 222 ? -22.711 -13.729 -40.633 1.00 24.00  ? 222 ALA A HB2    1 
ATOM   3485  H HB3    . ALA A 1 222 ? -21.547 -14.555 -39.933 1.00 24.00  ? 222 ALA A HB3    1 
ATOM   3486  N N      . TYR A 1 223 ? -21.945 -17.379 -39.087 1.00 17.71  ? 223 TYR A N      1 
ATOM   3487  C CA     . TYR A 1 223 ? -21.367 -18.702 -38.945 1.00 16.70  ? 223 TYR A CA     1 
ATOM   3488  C C      . TYR A 1 223 ? -22.432 -19.801 -39.031 1.00 19.30  ? 223 TYR A C      1 
ATOM   3489  O O      . TYR A 1 223 ? -22.230 -20.802 -39.717 1.00 18.24  ? 223 TYR A O      1 
ATOM   3490  C CB     . TYR A 1 223 ? -20.600 -18.867 -37.622 1.00 18.90  ? 223 TYR A CB     1 
ATOM   3491  C CG     . TYR A 1 223 ? -20.103 -20.283 -37.529 1.00 17.97  ? 223 TYR A CG     1 
ATOM   3492  C CD1    . TYR A 1 223 ? -18.998 -20.685 -38.258 1.00 19.51  ? 223 TYR A CD1    1 
ATOM   3493  C CD2    . TYR A 1 223 ? -20.788 -21.241 -36.789 1.00 19.46  ? 223 TYR A CD2    1 
ATOM   3494  C CE1    . TYR A 1 223 ? -18.557 -21.992 -38.227 1.00 21.48  ? 223 TYR A CE1    1 
ATOM   3495  C CE2    . TYR A 1 223 ? -20.353 -22.548 -36.750 1.00 20.41  ? 223 TYR A CE2    1 
ATOM   3496  C CZ     . TYR A 1 223 ? -19.238 -22.918 -37.470 1.00 24.19  ? 223 TYR A CZ     1 
ATOM   3497  O OH     . TYR A 1 223 ? -18.805 -24.222 -37.458 1.00 22.49  ? 223 TYR A OH     1 
ATOM   3498  H H      . TYR A 1 223 ? -21.825 -16.863 -38.409 1.00 21.25  ? 223 TYR A H      1 
ATOM   3499  H HA     . TYR A 1 223 ? -20.738 -18.844 -39.670 1.00 20.04  ? 223 TYR A HA     1 
ATOM   3500  H HB2    . TYR A 1 223 ? -19.839 -18.266 -37.606 1.00 22.68  ? 223 TYR A HB2    1 
ATOM   3501  H HB3    . TYR A 1 223 ? -21.192 -18.694 -36.874 1.00 22.68  ? 223 TYR A HB3    1 
ATOM   3502  H HD1    . TYR A 1 223 ? -18.539 -20.061 -38.773 1.00 23.42  ? 223 TYR A HD1    1 
ATOM   3503  H HD2    . TYR A 1 223 ? -21.542 -20.994 -36.305 1.00 23.35  ? 223 TYR A HD2    1 
ATOM   3504  H HE1    . TYR A 1 223 ? -17.807 -22.245 -38.715 1.00 25.77  ? 223 TYR A HE1    1 
ATOM   3505  H HE2    . TYR A 1 223 ? -20.813 -23.179 -36.244 1.00 24.49  ? 223 TYR A HE2    1 
ATOM   3506  H HH     . TYR A 1 223 ? -19.301 -24.685 -36.963 1.00 26.99  ? 223 TYR A HH     1 
ATOM   3507  N N      . PHE A 1 224 ? -23.560 -19.631 -38.339 1.00 21.59  ? 224 PHE A N      1 
ATOM   3508  C CA     . PHE A 1 224 ? -24.622 -20.648 -38.404 1.00 19.22  ? 224 PHE A CA     1 
ATOM   3509  C C      . PHE A 1 224 ? -25.161 -20.808 -39.832 1.00 19.93  ? 224 PHE A C      1 
ATOM   3510  O O      . PHE A 1 224 ? -25.489 -21.918 -40.257 1.00 21.07  ? 224 PHE A O      1 
ATOM   3511  C CB     . PHE A 1 224 ? -25.767 -20.303 -37.459 1.00 16.20  ? 224 PHE A CB     1 
ATOM   3512  C CG     . PHE A 1 224 ? -25.482 -20.640 -36.028 1.00 16.96  ? 224 PHE A CG     1 
ATOM   3513  C CD1    . PHE A 1 224 ? -25.388 -21.962 -35.629 1.00 22.33  ? 224 PHE A CD1    1 
ATOM   3514  C CD2    . PHE A 1 224 ? -25.307 -19.642 -35.086 1.00 23.57  ? 224 PHE A CD2    1 
ATOM   3515  C CE1    . PHE A 1 224 ? -25.121 -22.290 -34.305 1.00 23.65  ? 224 PHE A CE1    1 
ATOM   3516  C CE2    . PHE A 1 224 ? -25.035 -19.962 -33.754 1.00 23.42  ? 224 PHE A CE2    1 
ATOM   3517  C CZ     . PHE A 1 224 ? -24.937 -21.286 -33.372 1.00 21.92  ? 224 PHE A CZ     1 
ATOM   3518  H H      . PHE A 1 224 ? -23.736 -18.956 -37.836 1.00 25.91  ? 224 PHE A H      1 
ATOM   3519  H HA     . PHE A 1 224 ? -24.254 -21.502 -38.129 1.00 23.07  ? 224 PHE A HA     1 
ATOM   3520  H HB2    . PHE A 1 224 ? -25.941 -19.350 -37.511 1.00 19.44  ? 224 PHE A HB2    1 
ATOM   3521  H HB3    . PHE A 1 224 ? -26.557 -20.797 -37.730 1.00 19.44  ? 224 PHE A HB3    1 
ATOM   3522  H HD1    . PHE A 1 224 ? -25.504 -22.640 -36.255 1.00 26.80  ? 224 PHE A HD1    1 
ATOM   3523  H HD2    . PHE A 1 224 ? -25.365 -18.750 -35.343 1.00 28.28  ? 224 PHE A HD2    1 
ATOM   3524  H HE1    . PHE A 1 224 ? -25.057 -23.182 -34.049 1.00 28.38  ? 224 PHE A HE1    1 
ATOM   3525  H HE2    . PHE A 1 224 ? -24.916 -19.286 -33.127 1.00 28.11  ? 224 PHE A HE2    1 
ATOM   3526  H HZ     . PHE A 1 224 ? -24.763 -21.502 -32.484 1.00 26.30  ? 224 PHE A HZ     1 
ATOM   3527  N N      . ILE A 1 225 ? -25.260 -19.701 -40.560 1.00 19.51  ? 225 ILE A N      1 
ATOM   3528  C CA     . ILE A 1 225 ? -25.657 -19.755 -41.966 1.00 21.83  ? 225 ILE A CA     1 
ATOM   3529  C C      . ILE A 1 225 ? -24.627 -20.556 -42.767 1.00 22.48  ? 225 ILE A C      1 
ATOM   3530  O O      . ILE A 1 225 ? -24.989 -21.448 -43.537 1.00 21.86  ? 225 ILE A O      1 
ATOM   3531  C CB     . ILE A 1 225 ? -25.823 -18.336 -42.570 1.00 16.61  ? 225 ILE A CB     1 
ATOM   3532  C CG1    . ILE A 1 225 ? -27.051 -17.650 -41.967 1.00 18.45  ? 225 ILE A CG1    1 
ATOM   3533  C CG2    . ILE A 1 225 ? -25.945 -18.389 -44.111 1.00 20.38  ? 225 ILE A CG2    1 
ATOM   3534  C CD1    . ILE A 1 225 ? -27.225 -16.178 -42.373 1.00 19.63  ? 225 ILE A CD1    1 
ATOM   3535  H H      . ILE A 1 225 ? -25.104 -18.908 -40.267 1.00 23.42  ? 225 ILE A H      1 
ATOM   3536  H HA     . ILE A 1 225 ? -26.510 -20.211 -42.035 1.00 26.20  ? 225 ILE A HA     1 
ATOM   3537  H HB     . ILE A 1 225 ? -25.038 -17.813 -42.343 1.00 19.93  ? 225 ILE A HB     1 
ATOM   3538  H HG12   . ILE A 1 225 ? -27.845 -18.129 -42.252 1.00 22.14  ? 225 ILE A HG12   1 
ATOM   3539  H HG13   . ILE A 1 225 ? -26.980 -17.682 -41.000 1.00 22.14  ? 225 ILE A HG13   1 
ATOM   3540  H HG21   . ILE A 1 225 ? -26.240 -17.527 -44.440 1.00 24.45  ? 225 ILE A HG21   1 
ATOM   3541  H HG22   . ILE A 1 225 ? -25.079 -18.602 -44.492 1.00 24.45  ? 225 ILE A HG22   1 
ATOM   3542  H HG23   . ILE A 1 225 ? -26.591 -19.071 -44.352 1.00 24.45  ? 225 ILE A HG23   1 
ATOM   3543  H HD11   . ILE A 1 225 ? -27.868 -15.761 -41.778 1.00 23.55  ? 225 ILE A HD11   1 
ATOM   3544  H HD12   . ILE A 1 225 ? -26.369 -15.728 -42.301 1.00 23.55  ? 225 ILE A HD12   1 
ATOM   3545  H HD13   . ILE A 1 225 ? -27.545 -16.136 -43.288 1.00 23.55  ? 225 ILE A HD13   1 
ATOM   3546  N N      . LYS A 1 226 ? -23.344 -20.250 -42.589 1.00 18.54  ? 226 LYS A N      1 
ATOM   3547  C CA     . LYS A 1 226 ? -22.301 -20.941 -43.339 1.00 22.13  ? 226 LYS A CA     1 
ATOM   3548  C C      . LYS A 1 226 ? -22.313 -22.433 -43.011 1.00 22.71  ? 226 LYS A C      1 
ATOM   3549  O O      . LYS A 1 226 ? -22.142 -23.286 -43.888 1.00 20.34  ? 226 LYS A O      1 
ATOM   3550  C CB     . LYS A 1 226 ? -20.929 -20.330 -43.036 1.00 17.03  ? 226 LYS A CB     1 
ATOM   3551  C CG     . LYS A 1 226 ? -19.783 -20.940 -43.828 1.00 19.30  ? 226 LYS A CG     1 
ATOM   3552  C CD     . LYS A 1 226 ? -18.500 -20.124 -43.672 1.00 21.92  ? 226 LYS A CD     1 
ATOM   3553  C CE     . LYS A 1 226 ? -17.308 -20.837 -44.305 1.00 22.14  ? 226 LYS A CE     1 
ATOM   3554  N NZ     . LYS A 1 226 ? -17.453 -20.946 -45.784 1.00 21.02  ? 226 LYS A NZ     1 
ATOM   3555  H H      . LYS A 1 226 ? -23.054 -19.651 -42.044 1.00 22.25  ? 226 LYS A H      1 
ATOM   3556  H HA     . LYS A 1 226 ? -22.473 -20.840 -44.288 1.00 26.56  ? 226 LYS A HA     1 
ATOM   3557  H HB2    . LYS A 1 226 ? -20.955 -19.383 -43.233 1.00 20.43  ? 226 LYS A HB2    1 
ATOM   3558  H HB3    . LYS A 1 226 ? -20.735 -20.460 -42.095 1.00 20.43  ? 226 LYS A HB3    1 
ATOM   3559  H HG2    . LYS A 1 226 ? -19.613 -21.839 -43.505 1.00 23.16  ? 226 LYS A HG2    1 
ATOM   3560  H HG3    . LYS A 1 226 ? -20.019 -20.960 -44.769 1.00 23.16  ? 226 LYS A HG3    1 
ATOM   3561  H HD2    . LYS A 1 226 ? -18.610 -19.266 -44.110 1.00 26.30  ? 226 LYS A HD2    1 
ATOM   3562  H HD3    . LYS A 1 226 ? -18.313 -19.998 -42.729 1.00 26.30  ? 226 LYS A HD3    1 
ATOM   3563  H HE2    . LYS A 1 226 ? -16.499 -20.337 -44.116 1.00 26.56  ? 226 LYS A HE2    1 
ATOM   3564  H HE3    . LYS A 1 226 ? -17.241 -21.733 -43.940 1.00 26.56  ? 226 LYS A HE3    1 
ATOM   3565  H HZ1    . LYS A 1 226 ? -16.754 -21.377 -46.127 1.00 25.23  ? 226 LYS A HZ1    1 
ATOM   3566  H HZ2    . LYS A 1 226 ? -18.196 -21.393 -45.984 1.00 25.23  ? 226 LYS A HZ2    1 
ATOM   3567  H HZ3    . LYS A 1 226 ? -17.498 -20.134 -46.146 1.00 25.23  ? 226 LYS A HZ3    1 
ATOM   3568  N N      . GLU A 1 227 ? -22.559 -22.748 -41.744 1.00 19.60  ? 227 GLU A N      1 
ATOM   3569  C CA     . GLU A 1 227 ? -22.476 -24.119 -41.284 1.00 19.77  ? 227 GLU A CA     1 
ATOM   3570  C C      . GLU A 1 227 ? -23.727 -24.932 -41.642 1.00 20.53  ? 227 GLU A C      1 
ATOM   3571  O O      . GLU A 1 227 ? -23.617 -26.115 -41.960 1.00 21.21  ? 227 GLU A O      1 
ATOM   3572  C CB     . GLU A 1 227 ? -22.253 -24.153 -39.761 1.00 20.96  ? 227 GLU A CB     1 
ATOM   3573  C CG     . GLU A 1 227 ? -21.971 -25.549 -39.212 1.00 21.12  ? 227 GLU A CG     1 
ATOM   3574  C CD     . GLU A 1 227 ? -21.913 -25.591 -37.684 1.00 24.28  ? 227 GLU A CD     1 
ATOM   3575  O OE1    . GLU A 1 227 ? -22.900 -25.183 -37.035 1.00 22.59  ? 227 GLU A OE1    1 
ATOM   3576  O OE2    . GLU A 1 227 ? -20.881 -26.031 -37.133 1.00 26.90  ? 227 GLU A OE2    1 
ATOM   3577  H H      . GLU A 1 227 ? -22.776 -22.183 -41.133 1.00 23.52  ? 227 GLU A H      1 
ATOM   3578  H HA     . GLU A 1 227 ? -21.713 -24.546 -41.704 1.00 23.72  ? 227 GLU A HA     1 
ATOM   3579  H HB2    . GLU A 1 227 ? -21.494 -23.590 -39.543 1.00 25.15  ? 227 GLU A HB2    1 
ATOM   3580  H HB3    . GLU A 1 227 ? -23.049 -23.816 -39.321 1.00 25.15  ? 227 GLU A HB3    1 
ATOM   3581  H HG2    . GLU A 1 227 ? -22.674 -26.152 -39.498 1.00 25.35  ? 227 GLU A HG2    1 
ATOM   3582  H HG3    . GLU A 1 227 ? -21.115 -25.854 -39.552 1.00 25.35  ? 227 GLU A HG3    1 
ATOM   3583  N N      . GLN A 1 228 ? -24.903 -24.305 -41.602 1.00 20.37  ? 228 GLN A N      1 
ATOM   3584  C CA     . GLN A 1 228 ? -26.159 -25.063 -41.596 1.00 24.68  ? 228 GLN A CA     1 
ATOM   3585  C C      . GLN A 1 228 ? -27.208 -24.695 -42.656 1.00 29.95  ? 228 GLN A C      1 
ATOM   3586  O O      . GLN A 1 228 ? -28.158 -25.455 -42.841 1.00 26.82  ? 228 GLN A O      1 
ATOM   3587  C CB     . GLN A 1 228 ? -26.806 -24.946 -40.213 1.00 25.92  ? 228 GLN A CB     1 
ATOM   3588  C CG     . GLN A 1 228 ? -25.964 -25.573 -39.116 1.00 21.06  ? 228 GLN A CG     1 
ATOM   3589  C CD     . GLN A 1 228 ? -26.631 -25.531 -37.753 1.00 28.11  ? 228 GLN A CD     1 
ATOM   3590  O OE1    . GLN A 1 228 ? -27.856 -25.452 -37.644 1.00 27.30  ? 228 GLN A OE1    1 
ATOM   3591  N NE2    . GLN A 1 228 ? -25.823 -25.587 -36.705 1.00 25.34  ? 228 GLN A NE2    1 
ATOM   3592  H H      . GLN A 1 228 ? -25.003 -23.451 -41.578 1.00 24.45  ? 228 GLN A H      1 
ATOM   3593  H HA     . GLN A 1 228 ? -25.959 -26.002 -41.727 1.00 29.62  ? 228 GLN A HA     1 
ATOM   3594  H HB2    . GLN A 1 228 ? -26.930 -24.009 -39.998 1.00 31.10  ? 228 GLN A HB2    1 
ATOM   3595  H HB3    . GLN A 1 228 ? -27.664 -25.398 -40.228 1.00 31.10  ? 228 GLN A HB3    1 
ATOM   3596  H HG2    . GLN A 1 228 ? -25.798 -26.502 -39.339 1.00 25.27  ? 228 GLN A HG2    1 
ATOM   3597  H HG3    . GLN A 1 228 ? -25.123 -25.094 -39.052 1.00 25.27  ? 228 GLN A HG3    1 
ATOM   3598  H HE21   . GLN A 1 228 ? -24.973 -25.644 -36.820 1.00 30.41  ? 228 GLN A HE21   1 
ATOM   3599  H HE22   . GLN A 1 228 ? -26.149 -25.567 -35.909 1.00 30.41  ? 228 GLN A HE22   1 
ATOM   3600  N N      . GLU A 1 229 ? -27.072 -23.561 -43.340 1.00 22.10  ? 229 GLU A N      1 
ATOM   3601  C CA     . GLU A 1 229 ? -28.049 -23.207 -44.379 1.00 25.73  ? 229 GLU A CA     1 
ATOM   3602  C C      . GLU A 1 229 ? -27.582 -23.724 -45.733 1.00 27.90  ? 229 GLU A C      1 
ATOM   3603  O O      . GLU A 1 229 ? -26.460 -23.460 -46.161 1.00 23.42  ? 229 GLU A O      1 
ATOM   3604  C CB     . GLU A 1 229 ? -28.285 -21.697 -44.447 1.00 21.36  ? 229 GLU A CB     1 
ATOM   3605  C CG     . GLU A 1 229 ? -29.401 -21.292 -45.432 1.00 23.48  ? 229 GLU A CG     1 
ATOM   3606  C CD     . GLU A 1 229 ? -29.904 -19.870 -45.233 1.00 30.03  ? 229 GLU A CD     1 
ATOM   3607  O OE1    . GLU A 1 229 ? -29.290 -19.118 -44.440 1.00 25.53  ? 229 GLU A OE1    1 
ATOM   3608  O OE2    . GLU A 1 229 ? -30.930 -19.505 -45.859 1.00 22.31  ? 229 GLU A OE2    1 
ATOM   3609  H H      . GLU A 1 229 ? -26.440 -22.989 -43.229 1.00 26.52  ? 229 GLU A H      1 
ATOM   3610  H HA     . GLU A 1 229 ? -28.902 -23.622 -44.180 1.00 30.88  ? 229 GLU A HA     1 
ATOM   3611  H HB2    . GLU A 1 229 ? -28.536 -21.381 -43.565 1.00 25.63  ? 229 GLU A HB2    1 
ATOM   3612  H HB3    . GLU A 1 229 ? -27.465 -21.264 -44.732 1.00 25.63  ? 229 GLU A HB3    1 
ATOM   3613  H HG2    . GLU A 1 229 ? -29.060 -21.362 -46.337 1.00 28.18  ? 229 GLU A HG2    1 
ATOM   3614  H HG3    . GLU A 1 229 ? -30.154 -21.892 -45.316 1.00 28.18  ? 229 GLU A HG3    1 
ATOM   3615  N N      . GLU A 1 230 ? -28.447 -24.472 -46.404 1.00 30.43  ? 230 GLU A N      1 
ATOM   3616  C CA     . GLU A 1 230 ? -28.041 -25.153 -47.628 1.00 39.99  ? 230 GLU A CA     1 
ATOM   3617  C C      . GLU A 1 230 ? -27.547 -24.146 -48.664 1.00 26.73  ? 230 GLU A C      1 
ATOM   3618  O O      . GLU A 1 230 ? -28.189 -23.129 -48.901 1.00 26.74  ? 230 GLU A O      1 
ATOM   3619  C CB     . GLU A 1 230 ? -29.199 -25.977 -48.193 1.00 54.66  ? 230 GLU A CB     1 
ATOM   3620  C CG     . GLU A 1 230 ? -28.757 -27.104 -49.113 1.00 68.87  ? 230 GLU A CG     1 
ATOM   3621  C CD     . GLU A 1 230 ? -27.834 -28.097 -48.422 1.00 84.76  ? 230 GLU A CD     1 
ATOM   3622  O OE1    . GLU A 1 230 ? -27.888 -28.201 -47.176 1.00 85.20  ? 230 GLU A OE1    1 
ATOM   3623  O OE2    . GLU A 1 230 ? -27.047 -28.767 -49.126 1.00 80.46  ? 230 GLU A OE2    1 
ATOM   3624  H H      . GLU A 1 230 ? -29.266 -24.602 -46.177 1.00 36.52  ? 230 GLU A H      1 
ATOM   3625  H HA     . GLU A 1 230 ? -27.305 -25.749 -47.421 1.00 47.99  ? 230 GLU A HA     1 
ATOM   3626  H HB2    . GLU A 1 230 ? -29.693 -26.370 -47.456 1.00 65.59  ? 230 GLU A HB2    1 
ATOM   3627  H HB3    . GLU A 1 230 ? -29.780 -25.390 -48.702 1.00 65.59  ? 230 GLU A HB3    1 
ATOM   3628  H HG2    . GLU A 1 230 ? -29.540 -27.586 -49.421 1.00 82.64  ? 230 GLU A HG2    1 
ATOM   3629  H HG3    . GLU A 1 230 ? -28.280 -26.727 -49.869 1.00 82.64  ? 230 GLU A HG3    1 
ATOM   3630  N N      . GLY A 1 231 ? -26.383 -24.416 -49.240 1.00 30.21  ? 231 GLY A N      1 
ATOM   3631  C CA     . GLY A 1 231 ? -25.843 -23.575 -50.294 1.00 35.31  ? 231 GLY A CA     1 
ATOM   3632  C C      . GLY A 1 231 ? -24.758 -22.599 -49.862 1.00 32.33  ? 231 GLY A C      1 
ATOM   3633  O O      . GLY A 1 231 ? -24.054 -22.060 -50.713 1.00 28.11  ? 231 GLY A O      1 
ATOM   3634  H H      . GLY A 1 231 ? -25.884 -25.086 -49.036 1.00 36.25  ? 231 GLY A H      1 
ATOM   3635  H HA2    . GLY A 1 231 ? -25.465 -24.147 -50.980 1.00 42.37  ? 231 GLY A HA2    1 
ATOM   3636  H HA3    . GLY A 1 231 ? -26.560 -23.064 -50.700 1.00 42.37  ? 231 GLY A HA3    1 
ATOM   3637  N N      . PHE A 1 232 ? -24.604 -22.375 -48.555 1.00 26.91  ? 232 PHE A N      1 
ATOM   3638  C CA     . PHE A 1 232 ? -23.656 -21.361 -48.063 1.00 25.73  ? 232 PHE A CA     1 
ATOM   3639  C C      . PHE A 1 232 ? -22.329 -21.924 -47.554 1.00 25.87  ? 232 PHE A C      1 
ATOM   3640  O O      . PHE A 1 232 ? -21.485 -21.174 -47.064 1.00 22.41  ? 232 PHE A O      1 
ATOM   3641  C CB     . PHE A 1 232 ? -24.316 -20.537 -46.955 1.00 20.47  ? 232 PHE A CB     1 
ATOM   3642  C CG     . PHE A 1 232 ? -25.314 -19.557 -47.464 1.00 23.08  ? 232 PHE A CG     1 
ATOM   3643  C CD1    . PHE A 1 232 ? -24.904 -18.304 -47.898 1.00 22.57  ? 232 PHE A CD1    1 
ATOM   3644  C CD2    . PHE A 1 232 ? -26.658 -19.881 -47.540 1.00 24.03  ? 232 PHE A CD2    1 
ATOM   3645  C CE1    . PHE A 1 232 ? -25.817 -17.393 -48.385 1.00 25.07  ? 232 PHE A CE1    1 
ATOM   3646  C CE2    . PHE A 1 232 ? -27.573 -18.971 -48.028 1.00 27.95  ? 232 PHE A CE2    1 
ATOM   3647  C CZ     . PHE A 1 232 ? -27.148 -17.724 -48.453 1.00 24.91  ? 232 PHE A CZ     1 
ATOM   3648  H H      . PHE A 1 232 ? -25.031 -22.791 -47.935 1.00 32.29  ? 232 PHE A H      1 
ATOM   3649  H HA     . PHE A 1 232 ? -23.449 -20.747 -48.784 1.00 30.88  ? 232 PHE A HA     1 
ATOM   3650  H HB2    . PHE A 1 232 ? -24.773 -21.139 -46.347 1.00 24.56  ? 232 PHE A HB2    1 
ATOM   3651  H HB3    . PHE A 1 232 ? -23.633 -20.041 -46.477 1.00 24.56  ? 232 PHE A HB3    1 
ATOM   3652  H HD1    . PHE A 1 232 ? -24.004 -18.075 -47.857 1.00 27.09  ? 232 PHE A HD1    1 
ATOM   3653  H HD2    . PHE A 1 232 ? -26.947 -20.719 -47.258 1.00 28.84  ? 232 PHE A HD2    1 
ATOM   3654  H HE1    . PHE A 1 232 ? -25.531 -16.555 -48.669 1.00 30.08  ? 232 PHE A HE1    1 
ATOM   3655  H HE2    . PHE A 1 232 ? -28.475 -19.195 -48.072 1.00 33.54  ? 232 PHE A HE2    1 
ATOM   3656  H HZ     . PHE A 1 232 ? -27.764 -17.108 -48.778 1.00 29.89  ? 232 PHE A HZ     1 
ATOM   3657  N N      . GLU A 1 233 ? -22.138 -23.231 -47.712 1.00 23.99  ? 233 GLU A N      1 
ATOM   3658  C CA     . GLU A 1 233 ? -20.977 -23.937 -47.177 1.00 25.89  ? 233 GLU A CA     1 
ATOM   3659  C C      . GLU A 1 233 ? -19.664 -23.298 -47.618 1.00 25.21  ? 233 GLU A C      1 
ATOM   3660  O O      . GLU A 1 233 ? -18.698 -23.266 -46.859 1.00 23.51  ? 233 GLU A O      1 
ATOM   3661  C CB     . GLU A 1 233 ? -20.970 -25.417 -47.616 1.00 32.57  ? 233 GLU A CB     1 
ATOM   3662  C CG     . GLU A 1 233 ? -22.253 -26.219 -47.343 1.00 49.30  ? 233 GLU A CG     1 
ATOM   3663  C CD     . GLU A 1 233 ? -23.395 -25.929 -48.321 1.00 44.24  ? 233 GLU A CD     1 
ATOM   3664  O OE1    . GLU A 1 233 ? -23.149 -25.327 -49.386 1.00 39.92  ? 233 GLU A OE1    1 
ATOM   3665  O OE2    . GLU A 1 233 ? -24.548 -26.298 -48.012 1.00 52.82  ? 233 GLU A OE2    1 
ATOM   3666  H H      . GLU A 1 233 ? -22.677 -23.732 -48.147 1.00 28.78  ? 233 GLU A H      1 
ATOM   3667  H HA     . GLU A 1 233 ? -21.012 -23.912 -46.208 1.00 31.07  ? 233 GLU A HA     1 
ATOM   3668  H HB2    . GLU A 1 233 ? -20.799 -25.452 -48.570 1.00 39.08  ? 233 GLU A HB2    1 
ATOM   3669  H HB3    . GLU A 1 233 ? -20.249 -25.866 -47.147 1.00 39.08  ? 233 GLU A HB3    1 
ATOM   3670  H HG2    . GLU A 1 233 ? -22.046 -27.165 -47.406 1.00 59.16  ? 233 GLU A HG2    1 
ATOM   3671  H HG3    . GLU A 1 233 ? -22.565 -26.013 -46.449 1.00 59.16  ? 233 GLU A HG3    1 
ATOM   3672  N N      . ASP A 1 234 ? -19.629 -22.810 -48.855 1.00 23.00  ? 234 ASP A N      1 
ATOM   3673  C CA     . ASP A 1 234 ? -18.392 -22.287 -49.431 1.00 24.77  ? 234 ASP A CA     1 
ATOM   3674  C C      . ASP A 1 234 ? -18.438 -20.763 -49.622 1.00 21.54  ? 234 ASP A C      1 
ATOM   3675  O O      . ASP A 1 234 ? -17.663 -20.208 -50.392 1.00 24.98  ? 234 ASP A O      1 
ATOM   3676  C CB     . ASP A 1 234 ? -18.105 -22.997 -50.764 1.00 26.98  ? 234 ASP A CB     1 
ATOM   3677  C CG     . ASP A 1 234 ? -17.901 -24.506 -50.596 1.00 32.70  ? 234 ASP A CG     1 
ATOM   3678  O OD1    . ASP A 1 234 ? -17.323 -24.929 -49.574 1.00 32.22  ? 234 ASP A OD1    1 
ATOM   3679  O OD2    . ASP A 1 234 ? -18.320 -25.274 -51.486 1.00 36.04  ? 234 ASP A OD2    1 
ATOM   3680  H H      . ASP A 1 234 ? -20.307 -22.770 -49.382 1.00 27.60  ? 234 ASP A H      1 
ATOM   3681  H HA     . ASP A 1 234 ? -17.650 -22.480 -48.839 1.00 29.72  ? 234 ASP A HA     1 
ATOM   3682  H HB2    . ASP A 1 234 ? -18.855 -22.860 -51.364 1.00 32.37  ? 234 ASP A HB2    1 
ATOM   3683  H HB3    . ASP A 1 234 ? -17.297 -22.628 -51.153 1.00 32.37  ? 234 ASP A HB3    1 
ATOM   3684  N N      . VAL A 1 235 ? -19.350 -20.093 -48.920 1.00 20.32  ? 235 VAL A N      1 
ATOM   3685  C CA     . VAL A 1 235 ? -19.433 -18.630 -48.955 1.00 22.68  ? 235 VAL A CA     1 
ATOM   3686  C C      . VAL A 1 235 ? -18.720 -18.103 -47.711 1.00 23.37  ? 235 VAL A C      1 
ATOM   3687  O O      . VAL A 1 235 ? -18.893 -18.646 -46.620 1.00 18.27  ? 235 VAL A O      1 
ATOM   3688  C CB     . VAL A 1 235 ? -20.892 -18.128 -49.001 1.00 18.21  ? 235 VAL A CB     1 
ATOM   3689  C CG1    . VAL A 1 235 ? -20.945 -16.604 -49.085 1.00 22.96  ? 235 VAL A CG1    1 
ATOM   3690  C CG2    . VAL A 1 235 ? -21.629 -18.735 -50.201 1.00 26.75  ? 235 VAL A CG2    1 
ATOM   3691  H H      . VAL A 1 235 ? -19.937 -20.462 -48.411 1.00 24.39  ? 235 VAL A H      1 
ATOM   3692  H HA     . VAL A 1 235 ? -18.974 -18.288 -49.738 1.00 27.22  ? 235 VAL A HA     1 
ATOM   3693  H HB     . VAL A 1 235 ? -21.351 -18.404 -48.192 1.00 21.86  ? 235 VAL A HB     1 
ATOM   3694  H HG11   . VAL A 1 235 ? -21.872 -16.324 -49.139 1.00 27.56  ? 235 VAL A HG11   1 
ATOM   3695  H HG12   . VAL A 1 235 ? -20.531 -16.224 -48.295 1.00 27.56  ? 235 VAL A HG12   1 
ATOM   3696  H HG13   . VAL A 1 235 ? -20.467 -16.316 -49.879 1.00 27.56  ? 235 VAL A HG13   1 
ATOM   3697  H HG21   . VAL A 1 235 ? -22.526 -18.368 -50.238 1.00 32.10  ? 235 VAL A HG21   1 
ATOM   3698  H HG22   . VAL A 1 235 ? -21.147 -18.512 -51.013 1.00 32.10  ? 235 VAL A HG22   1 
ATOM   3699  H HG23   . VAL A 1 235 ? -21.669 -19.698 -50.093 1.00 32.10  ? 235 VAL A HG23   1 
ATOM   3700  N N      . SER A 1 236 ? -17.900 -17.070 -47.874 1.00 21.62  ? 236 SER A N      1 
ATOM   3701  C CA     . SER A 1 236 ? -17.123 -16.558 -46.748 1.00 20.71  ? 236 SER A CA     1 
ATOM   3702  C C      . SER A 1 236 ? -18.024 -15.891 -45.725 1.00 18.81  ? 236 SER A C      1 
ATOM   3703  O O      . SER A 1 236 ? -19.109 -15.393 -46.049 1.00 16.51  ? 236 SER A O      1 
ATOM   3704  C CB     . SER A 1 236 ? -16.063 -15.561 -47.216 1.00 21.71  ? 236 SER A CB     1 
ATOM   3705  O OG     . SER A 1 236 ? -16.676 -14.372 -47.677 1.00 20.95  ? 236 SER A OG     1 
ATOM   3706  H H      . SER A 1 236 ? -17.776 -16.652 -48.615 1.00 25.95  ? 236 SER A H      1 
ATOM   3707  H HA     . SER A 1 236 ? -16.669 -17.297 -46.314 1.00 24.85  ? 236 SER A HA     1 
ATOM   3708  H HB2    . SER A 1 236 ? -15.477 -15.348 -46.473 1.00 26.05  ? 236 SER A HB2    1 
ATOM   3709  H HB3    . SER A 1 236 ? -15.553 -15.957 -47.940 1.00 26.05  ? 236 SER A HB3    1 
ATOM   3710  H HG     . SER A 1 236 ? -16.090 -13.821 -47.919 1.00 25.14  ? 236 SER A HG     1 
ATOM   3711  N N      . ILE A 1 237 ? -17.560 -15.874 -44.480 1.00 19.47  ? 237 ILE A N      1 
ATOM   3712  C CA     . ILE A 1 237 ? -18.265 -15.174 -43.420 1.00 17.86  ? 237 ILE A CA     1 
ATOM   3713  C C      . ILE A 1 237 ? -18.499 -13.717 -43.821 1.00 16.04  ? 237 ILE A C      1 
ATOM   3714  O O      . ILE A 1 237 ? -19.597 -13.180 -43.654 1.00 15.88  ? 237 ILE A O      1 
ATOM   3715  C CB     . ILE A 1 237 ? -17.472 -15.248 -42.092 1.00 16.48  ? 237 ILE A CB     1 
ATOM   3716  C CG1    . ILE A 1 237 ? -17.461 -16.693 -41.559 1.00 17.88  ? 237 ILE A CG1    1 
ATOM   3717  C CG2    . ILE A 1 237 ? -18.031 -14.271 -41.059 1.00 19.32  ? 237 ILE A CG2    1 
ATOM   3718  C CD1    . ILE A 1 237 ? -18.837 -17.221 -41.119 1.00 20.86  ? 237 ILE A CD1    1 
ATOM   3719  H H      . ILE A 1 237 ? -16.836 -16.262 -44.225 1.00 23.37  ? 237 ILE A H      1 
ATOM   3720  H HA     . ILE A 1 237 ? -19.131 -15.589 -43.285 1.00 21.44  ? 237 ILE A HA     1 
ATOM   3721  H HB     . ILE A 1 237 ? -16.555 -14.992 -42.278 1.00 19.77  ? 237 ILE A HB     1 
ATOM   3722  H HG12   . ILE A 1 237 ? -17.131 -17.279 -42.258 1.00 21.46  ? 237 ILE A HG12   1 
ATOM   3723  H HG13   . ILE A 1 237 ? -16.870 -16.735 -40.791 1.00 21.46  ? 237 ILE A HG13   1 
ATOM   3724  H HG21   . ILE A 1 237 ? -17.723 -14.537 -40.178 1.00 23.19  ? 237 ILE A HG21   1 
ATOM   3725  H HG22   . ILE A 1 237 ? -17.715 -13.377 -41.262 1.00 23.19  ? 237 ILE A HG22   1 
ATOM   3726  H HG23   . ILE A 1 237 ? -19.000 -14.298 -41.091 1.00 23.19  ? 237 ILE A HG23   1 
ATOM   3727  H HD11   . ILE A 1 237 ? -18.724 -18.102 -40.729 1.00 25.03  ? 237 ILE A HD11   1 
ATOM   3728  H HD12   . ILE A 1 237 ? -19.215 -16.616 -40.462 1.00 25.03  ? 237 ILE A HD12   1 
ATOM   3729  H HD13   . ILE A 1 237 ? -19.419 -17.277 -41.892 1.00 25.03  ? 237 ILE A HD13   1 
ATOM   3730  N N      . LYS A 1 238 ? -17.458 -13.084 -44.354 1.00 15.93  ? 238 LYS A N      1 
ATOM   3731  C CA     . LYS A 1 238 ? -17.540 -11.701 -44.796 1.00 17.75  ? 238 LYS A CA     1 
ATOM   3732  C C      . LYS A 1 238 ? -18.673 -11.507 -45.807 1.00 17.89  ? 238 LYS A C      1 
ATOM   3733  O O      . LYS A 1 238 ? -19.459 -10.566 -45.700 1.00 19.27  ? 238 LYS A O      1 
ATOM   3734  C CB     . LYS A 1 238 ? -16.187 -11.275 -45.386 1.00 22.64  ? 238 LYS A CB     1 
ATOM   3735  C CG     . LYS A 1 238 ? -16.182 -9.999  -46.177 1.00 34.87  ? 238 LYS A CG     1 
ATOM   3736  C CD     . LYS A 1 238 ? -14.768 -9.669  -46.638 1.00 35.92  ? 238 LYS A CD     1 
ATOM   3737  C CE     . LYS A 1 238 ? -14.724 -8.325  -47.353 1.00 50.34  ? 238 LYS A CE     1 
ATOM   3738  N NZ     . LYS A 1 238 ? -13.335 -7.814  -47.497 1.00 70.04  ? 238 LYS A NZ     1 
ATOM   3739  H H      . LYS A 1 238 ? -16.684 -13.441 -44.471 1.00 19.11  ? 238 LYS A H      1 
ATOM   3740  H HA     . LYS A 1 238 ? -17.723 -11.136 -44.030 1.00 21.30  ? 238 LYS A HA     1 
ATOM   3741  H HB2    . LYS A 1 238 ? -15.558 -11.164 -44.656 1.00 27.16  ? 238 LYS A HB2    1 
ATOM   3742  H HB3    . LYS A 1 238 ? -15.876 -11.980 -45.975 1.00 27.16  ? 238 LYS A HB3    1 
ATOM   3743  H HG2    . LYS A 1 238 ? -16.742 -10.096 -46.963 1.00 41.84  ? 238 LYS A HG2    1 
ATOM   3744  H HG3    . LYS A 1 238 ? -16.498 -9.272  -45.619 1.00 41.84  ? 238 LYS A HG3    1 
ATOM   3745  H HD2    . LYS A 1 238 ? -14.181 -9.624  -45.867 1.00 43.11  ? 238 LYS A HD2    1 
ATOM   3746  H HD3    . LYS A 1 238 ? -14.463 -10.353 -47.255 1.00 43.11  ? 238 LYS A HD3    1 
ATOM   3747  H HE2    . LYS A 1 238 ? -15.105 -8.422  -48.240 1.00 60.41  ? 238 LYS A HE2    1 
ATOM   3748  H HE3    . LYS A 1 238 ? -15.230 -7.676  -46.840 1.00 60.41  ? 238 LYS A HE3    1 
ATOM   3749  H HZ1    . LYS A 1 238 ? -12.846 -8.390  -47.968 1.00 84.05  ? 238 LYS A HZ1    1 
ATOM   3750  H HZ2    . LYS A 1 238 ? -13.342 -7.030  -47.917 1.00 84.05  ? 238 LYS A HZ2    1 
ATOM   3751  H HZ3    . LYS A 1 238 ? -12.965 -7.709  -46.694 1.00 84.05  ? 238 LYS A HZ3    1 
ATOM   3752  N N      . ASP A 1 239 ? -18.767 -12.404 -46.783 1.00 17.82  ? 239 ASP A N      1 
ATOM   3753  C CA     . ASP A 1 239 ? -19.782 -12.262 -47.825 1.00 19.23  ? 239 ASP A CA     1 
ATOM   3754  C C      . ASP A 1 239 ? -21.177 -12.555 -47.284 1.00 17.65  ? 239 ASP A C      1 
ATOM   3755  O O      . ASP A 1 239 ? -22.151 -11.926 -47.698 1.00 20.23  ? 239 ASP A O      1 
ATOM   3756  C CB     . ASP A 1 239 ? -19.465 -13.173 -49.016 1.00 20.75  ? 239 ASP A CB     1 
ATOM   3757  C CG     . ASP A 1 239 ? -18.313 -12.647 -49.854 1.00 27.53  ? 239 ASP A CG     1 
ATOM   3758  O OD1    . ASP A 1 239 ? -18.045 -11.428 -49.779 1.00 26.81  ? 239 ASP A OD1    1 
ATOM   3759  O OD2    . ASP A 1 239 ? -17.684 -13.441 -50.586 1.00 23.68  ? 239 ASP A OD2    1 
ATOM   3760  H H      . ASP A 1 239 ? -18.263 -13.096 -46.866 1.00 21.39  ? 239 ASP A H      1 
ATOM   3761  H HA     . ASP A 1 239 ? -19.786 -11.344 -48.136 1.00 23.07  ? 239 ASP A HA     1 
ATOM   3762  H HB2    . ASP A 1 239 ? -19.221 -14.052 -48.687 1.00 24.90  ? 239 ASP A HB2    1 
ATOM   3763  H HB3    . ASP A 1 239 ? -20.248 -13.235 -49.585 1.00 24.90  ? 239 ASP A HB3    1 
ATOM   3764  N N      . ILE A 1 240 ? -21.274 -13.490 -46.343 1.00 19.00  ? 240 ILE A N      1 
ATOM   3765  C CA     . ILE A 1 240 ? -22.553 -13.779 -45.703 1.00 15.51  ? 240 ILE A CA     1 
ATOM   3766  C C      . ILE A 1 240 ? -23.025 -12.558 -44.909 1.00 20.41  ? 240 ILE A C      1 
ATOM   3767  O O      . ILE A 1 240 ? -24.176 -12.133 -45.040 1.00 19.57  ? 240 ILE A O      1 
ATOM   3768  C CB     . ILE A 1 240 ? -22.449 -15.039 -44.797 1.00 17.03  ? 240 ILE A CB     1 
ATOM   3769  C CG1    . ILE A 1 240 ? -22.198 -16.272 -45.673 1.00 19.27  ? 240 ILE A CG1    1 
ATOM   3770  C CG2    . ILE A 1 240 ? -23.714 -15.215 -43.971 1.00 21.80  ? 240 ILE A CG2    1 
ATOM   3771  C CD1    . ILE A 1 240 ? -21.890 -17.562 -44.905 1.00 17.79  ? 240 ILE A CD1    1 
ATOM   3772  H H      . ILE A 1 240 ? -20.618 -13.968 -46.059 1.00 22.80  ? 240 ILE A H      1 
ATOM   3773  H HA     . ILE A 1 240 ? -23.213 -13.961 -46.390 1.00 18.62  ? 240 ILE A HA     1 
ATOM   3774  H HB     . ILE A 1 240 ? -21.697 -14.927 -44.194 1.00 20.44  ? 240 ILE A HB     1 
ATOM   3775  H HG12   . ILE A 1 240 ? -22.992 -16.435 -46.206 1.00 23.12  ? 240 ILE A HG12   1 
ATOM   3776  H HG13   . ILE A 1 240 ? -21.449 -16.092 -46.259 1.00 23.12  ? 240 ILE A HG13   1 
ATOM   3777  H HG21   . ILE A 1 240 ? -23.709 -16.094 -43.563 1.00 26.17  ? 240 ILE A HG21   1 
ATOM   3778  H HG22   . ILE A 1 240 ? -23.741 -14.535 -43.280 1.00 26.17  ? 240 ILE A HG22   1 
ATOM   3779  H HG23   . ILE A 1 240 ? -24.485 -15.127 -44.553 1.00 26.17  ? 240 ILE A HG23   1 
ATOM   3780  H HD11   . ILE A 1 240 ? -21.573 -18.233 -45.530 1.00 21.34  ? 240 ILE A HD11   1 
ATOM   3781  H HD12   . ILE A 1 240 ? -21.206 -17.376 -44.243 1.00 21.34  ? 240 ILE A HD12   1 
ATOM   3782  H HD13   . ILE A 1 240 ? -22.698 -17.872 -44.468 1.00 21.34  ? 240 ILE A HD13   1 
ATOM   3783  N N      . VAL A 1 241 ? -22.136 -11.971 -44.109 1.00 18.80  ? 241 VAL A N      1 
ATOM   3784  C CA     . VAL A 1 241 ? -22.485 -10.770 -43.357 1.00 15.56  ? 241 VAL A CA     1 
ATOM   3785  C C      . VAL A 1 241 ? -22.971 -9.647  -44.279 1.00 16.87  ? 241 VAL A C      1 
ATOM   3786  O O      . VAL A 1 241 ? -23.994 -9.022  -44.011 1.00 17.71  ? 241 VAL A O      1 
ATOM   3787  C CB     . VAL A 1 241 ? -21.290 -10.276 -42.519 1.00 18.21  ? 241 VAL A CB     1 
ATOM   3788  C CG1    . VAL A 1 241 ? -21.576 -8.912  -41.909 1.00 21.66  ? 241 VAL A CG1    1 
ATOM   3789  C CG2    . VAL A 1 241 ? -20.970 -11.291 -41.431 1.00 20.33  ? 241 VAL A CG2    1 
ATOM   3790  H H      . VAL A 1 241 ? -21.331 -12.247 -43.986 1.00 22.56  ? 241 VAL A H      1 
ATOM   3791  H HA     . VAL A 1 241 ? -23.207 -10.984 -42.746 1.00 18.67  ? 241 VAL A HA     1 
ATOM   3792  H HB     . VAL A 1 241 ? -20.512 -10.193 -43.093 1.00 21.85  ? 241 VAL A HB     1 
ATOM   3793  H HG11   . VAL A 1 241 ? -20.967 -8.767  -41.168 1.00 25.99  ? 241 VAL A HG11   1 
ATOM   3794  H HG12   . VAL A 1 241 ? -21.444 -8.227  -42.583 1.00 25.99  ? 241 VAL A HG12   1 
ATOM   3795  H HG13   . VAL A 1 241 ? -22.492 -8.895  -41.590 1.00 25.99  ? 241 VAL A HG13   1 
ATOM   3796  H HG21   . VAL A 1 241 ? -20.096 -11.090 -41.061 1.00 24.40  ? 241 VAL A HG21   1 
ATOM   3797  H HG22   . VAL A 1 241 ? -21.645 -11.231 -40.737 1.00 24.40  ? 241 VAL A HG22   1 
ATOM   3798  H HG23   . VAL A 1 241 ? -20.969 -12.181 -41.814 1.00 24.40  ? 241 VAL A HG23   1 
ATOM   3799  N N      . HIS A 1 242 ? -22.238 -9.384  -45.354 1.00 18.20  ? 242 HIS A N      1 
ATOM   3800  C CA     . HIS A 1 242 ? -22.613 -8.310  -46.267 1.00 20.17  ? 242 HIS A CA     1 
ATOM   3801  C C      . HIS A 1 242 ? -23.998 -8.581  -46.870 1.00 20.72  ? 242 HIS A C      1 
ATOM   3802  O O      . HIS A 1 242 ? -24.824 -7.676  -46.950 1.00 23.54  ? 242 HIS A O      1 
ATOM   3803  C CB     . HIS A 1 242 ? -21.559 -8.135  -47.371 1.00 20.81  ? 242 HIS A CB     1 
ATOM   3804  C CG     . HIS A 1 242 ? -21.688 -6.853  -48.139 1.00 24.22  ? 242 HIS A CG     1 
ATOM   3805  N ND1    . HIS A 1 242 ? -22.511 -6.719  -49.238 1.00 24.10  ? 242 HIS A ND1    1 
ATOM   3806  C CD2    . HIS A 1 242 ? -21.089 -5.648  -47.972 1.00 24.18  ? 242 HIS A CD2    1 
ATOM   3807  C CE1    . HIS A 1 242 ? -22.422 -5.486  -49.706 1.00 25.45  ? 242 HIS A CE1    1 
ATOM   3808  N NE2    . HIS A 1 242 ? -21.562 -4.816  -48.959 1.00 21.77  ? 242 HIS A NE2    1 
ATOM   3809  H H      . HIS A 1 242 ? -21.524 -9.809  -45.577 1.00 21.84  ? 242 HIS A H      1 
ATOM   3810  H HA     . HIS A 1 242 ? -22.663 -7.479  -45.769 1.00 24.21  ? 242 HIS A HA     1 
ATOM   3811  H HB2    . HIS A 1 242 ? -20.678 -8.150  -46.966 1.00 24.98  ? 242 HIS A HB2    1 
ATOM   3812  H HB3    . HIS A 1 242 ? -21.643 -8.867  -48.001 1.00 24.98  ? 242 HIS A HB3    1 
ATOM   3813  H HD1    . HIS A 1 242 ? -23.011 -7.339  -49.562 1.00 28.92  ? 242 HIS A HD1    1 
ATOM   3814  H HD2    . HIS A 1 242 ? -20.475 -5.425  -47.310 1.00 29.02  ? 242 HIS A HD2    1 
ATOM   3815  H HE1    . HIS A 1 242 ? -22.880 -5.150  -50.442 1.00 30.54  ? 242 HIS A HE1    1 
ATOM   3816  N N      . GLU A 1 243 ? -24.280 -9.826  -47.250 1.00 20.76  ? 243 GLU A N      1 
ATOM   3817  C CA     . GLU A 1 243 ? -25.587 -10.112 -47.838 1.00 21.58  ? 243 GLU A CA     1 
ATOM   3818  C C      . GLU A 1 243 ? -26.713 -10.017 -46.800 1.00 22.28  ? 243 GLU A C      1 
ATOM   3819  O O      . GLU A 1 243 ? -27.792 -9.526  -47.109 1.00 20.82  ? 243 GLU A O      1 
ATOM   3820  C CB     . GLU A 1 243 ? -25.617 -11.485 -48.511 1.00 21.89  ? 243 GLU A CB     1 
ATOM   3821  C CG     . GLU A 1 243 ? -26.923 -11.679 -49.298 1.00 26.20  ? 243 GLU A CG     1 
ATOM   3822  C CD     . GLU A 1 243 ? -27.131 -13.088 -49.816 1.00 28.88  ? 243 GLU A CD     1 
ATOM   3823  O OE1    . GLU A 1 243 ? -26.169 -13.883 -49.832 1.00 25.37  ? 243 GLU A OE1    1 
ATOM   3824  O OE2    . GLU A 1 243 ? -28.283 -13.392 -50.202 1.00 31.02  ? 243 GLU A OE2    1 
ATOM   3825  H H      . GLU A 1 243 ? -23.752 -10.502 -47.182 1.00 24.91  ? 243 GLU A H      1 
ATOM   3826  H HA     . GLU A 1 243 ? -25.767 -9.450  -48.524 1.00 25.90  ? 243 GLU A HA     1 
ATOM   3827  H HB2    . GLU A 1 243 ? -24.873 -11.557 -49.129 1.00 26.27  ? 243 GLU A HB2    1 
ATOM   3828  H HB3    . GLU A 1 243 ? -25.562 -12.177 -47.834 1.00 26.27  ? 243 GLU A HB3    1 
ATOM   3829  H HG2    . GLU A 1 243 ? -27.677 -11.471 -48.727 1.00 31.44  ? 243 GLU A HG2    1 
ATOM   3830  H HG3    . GLU A 1 243 ? -26.917 -11.082 -50.062 1.00 31.44  ? 243 GLU A HG3    1 
ATOM   3831  N N      . MET A 1 244 ? -26.464 -10.464 -45.575 1.00 21.44  ? 244 MET A N      1 
ATOM   3832  C CA     . MET A 1 244 ? -27.444 -10.306 -44.500 1.00 20.82  ? 244 MET A CA     1 
ATOM   3833  C C      . MET A 1 244 ? -27.962 -8.874  -44.434 1.00 23.73  ? 244 MET A C      1 
ATOM   3834  O O      . MET A 1 244 ? -29.173 -8.627  -44.449 1.00 20.87  ? 244 MET A O      1 
ATOM   3835  C CB     . MET A 1 244 ? -26.829 -10.699 -43.147 1.00 17.60  ? 244 MET A CB     1 
ATOM   3836  C CG     . MET A 1 244 ? -26.711 -12.193 -42.895 1.00 19.30  ? 244 MET A CG     1 
ATOM   3837  S SD     . MET A 1 244 ? -25.747 -12.593 -41.400 1.00 21.90  ? 244 MET A SD     1 
ATOM   3838  C CE     . MET A 1 244 ? -26.564 -11.610 -40.147 1.00 23.70  ? 244 MET A CE     1 
ATOM   3839  H H      . MET A 1 244 ? -25.739 -10.861 -45.338 1.00 25.72  ? 244 MET A H      1 
ATOM   3840  H HA     . MET A 1 244 ? -28.191 -10.901 -44.670 1.00 24.99  ? 244 MET A HA     1 
ATOM   3841  H HB2    . MET A 1 244 ? -25.937 -10.323 -43.092 1.00 21.12  ? 244 MET A HB2    1 
ATOM   3842  H HB3    . MET A 1 244 ? -27.382 -10.327 -42.442 1.00 21.12  ? 244 MET A HB3    1 
ATOM   3843  H HG2    . MET A 1 244 ? -27.599 -12.566 -42.786 1.00 23.16  ? 244 MET A HG2    1 
ATOM   3844  H HG3    . MET A 1 244 ? -26.271 -12.607 -43.654 1.00 23.16  ? 244 MET A HG3    1 
ATOM   3845  H HE1    . MET A 1 244 ? -26.171 -11.812 -39.283 1.00 28.44  ? 244 MET A HE1    1 
ATOM   3846  H HE2    . MET A 1 244 ? -26.442 -10.670 -40.354 1.00 28.44  ? 244 MET A HE2    1 
ATOM   3847  H HE3    . MET A 1 244 ? -27.509 -11.828 -40.139 1.00 28.44  ? 244 MET A HE3    1 
ATOM   3848  N N      . PHE A 1 245 ? -27.041 -7.917  -44.375 1.00 22.94  ? 245 PHE A N      1 
ATOM   3849  C CA     . PHE A 1 245 ? -27.436 -6.530  -44.182 1.00 20.88  ? 245 PHE A CA     1 
ATOM   3850  C C      . PHE A 1 245 ? -27.981 -5.894  -45.463 1.00 20.70  ? 245 PHE A C      1 
ATOM   3851  O O      . PHE A 1 245 ? -28.599 -4.829  -45.403 1.00 24.51  ? 245 PHE A O      1 
ATOM   3852  C CB     . PHE A 1 245 ? -26.257 -5.721  -43.638 1.00 22.73  ? 245 PHE A CB     1 
ATOM   3853  C CG     . PHE A 1 245 ? -25.926 -6.036  -42.204 1.00 19.22  ? 245 PHE A CG     1 
ATOM   3854  C CD1    . PHE A 1 245 ? -26.818 -5.729  -41.195 1.00 23.53  ? 245 PHE A CD1    1 
ATOM   3855  C CD2    . PHE A 1 245 ? -24.729 -6.647  -41.866 1.00 21.17  ? 245 PHE A CD2    1 
ATOM   3856  C CE1    . PHE A 1 245 ? -26.524 -6.019  -39.877 1.00 23.88  ? 245 PHE A CE1    1 
ATOM   3857  C CE2    . PHE A 1 245 ? -24.429 -6.939  -40.539 1.00 20.56  ? 245 PHE A CE2    1 
ATOM   3858  C CZ     . PHE A 1 245 ? -25.330 -6.622  -39.549 1.00 23.66  ? 245 PHE A CZ     1 
ATOM   3859  H H      . PHE A 1 245 ? -26.193 -8.043  -44.443 1.00 27.52  ? 245 PHE A H      1 
ATOM   3860  H HA     . PHE A 1 245 ? -28.143 -6.499  -43.519 1.00 25.05  ? 245 PHE A HA     1 
ATOM   3861  H HB2    . PHE A 1 245 ? -25.471 -5.914  -44.173 1.00 27.28  ? 245 PHE A HB2    1 
ATOM   3862  H HB3    . PHE A 1 245 ? -26.471 -4.777  -43.695 1.00 27.28  ? 245 PHE A HB3    1 
ATOM   3863  H HD1    . PHE A 1 245 ? -27.627 -5.321  -41.406 1.00 28.24  ? 245 PHE A HD1    1 
ATOM   3864  H HD2    . PHE A 1 245 ? -24.118 -6.861  -42.533 1.00 25.41  ? 245 PHE A HD2    1 
ATOM   3865  H HE1    . PHE A 1 245 ? -27.134 -5.804  -39.208 1.00 28.66  ? 245 PHE A HE1    1 
ATOM   3866  H HE2    . PHE A 1 245 ? -23.622 -7.347  -40.322 1.00 24.67  ? 245 PHE A HE2    1 
ATOM   3867  H HZ     . PHE A 1 245 ? -25.134 -6.816  -38.661 1.00 28.39  ? 245 PHE A HZ     1 
ATOM   3868  N N      . SER A 1 246 ? -27.762 -6.532  -46.611 1.00 21.48  ? 246 SER A N      1 
ATOM   3869  C CA     . SER A 1 246 ? -28.348 -6.047  -47.861 1.00 23.15  ? 246 SER A CA     1 
ATOM   3870  C C      . SER A 1 246 ? -29.885 -6.096  -47.817 1.00 28.57  ? 246 SER A C      1 
ATOM   3871  O O      . SER A 1 246 ? -30.547 -5.428  -48.614 1.00 29.19  ? 246 SER A O      1 
ATOM   3872  C CB     . SER A 1 246 ? -27.823 -6.841  -49.072 1.00 21.41  ? 246 SER A CB     1 
ATOM   3873  O OG     . SER A 1 246 ? -28.481 -8.090  -49.252 1.00 24.79  ? 246 SER A OG     1 
ATOM   3874  H H      . SER A 1 246 ? -27.282 -7.241  -46.695 1.00 25.77  ? 246 SER A H      1 
ATOM   3875  H HA     . SER A 1 246 ? -28.088 -5.121  -47.984 1.00 27.79  ? 246 SER A HA     1 
ATOM   3876  H HB2    . SER A 1 246 ? -27.953 -6.306  -49.871 1.00 25.69  ? 246 SER A HB2    1 
ATOM   3877  H HB3    . SER A 1 246 ? -26.876 -7.007  -48.944 1.00 25.69  ? 246 SER A HB3    1 
ATOM   3878  H HG     . SER A 1 246 ? -28.380 -8.569  -48.570 1.00 29.74  ? 246 SER A HG     1 
ATOM   3879  N N      . TYR A 1 247 ? -30.448 -6.865  -46.881 1.00 23.24  ? 247 TYR A N      1 
ATOM   3880  C CA     . TYR A 1 247 ? -31.905 -6.968  -46.743 1.00 26.09  ? 247 TYR A CA     1 
ATOM   3881  C C      . TYR A 1 247 ? -32.460 -6.063  -45.654 1.00 30.09  ? 247 TYR A C      1 
ATOM   3882  O O      . TYR A 1 247 ? -33.619 -6.199  -45.268 1.00 26.80  ? 247 TYR A O      1 
ATOM   3883  C CB     . TYR A 1 247 ? -32.309 -8.423  -46.465 1.00 24.44  ? 247 TYR A CB     1 
ATOM   3884  C CG     . TYR A 1 247 ? -31.809 -9.366  -47.531 1.00 21.77  ? 247 TYR A CG     1 
ATOM   3885  C CD1    . TYR A 1 247 ? -32.226 -9.231  -48.849 1.00 30.75  ? 247 TYR A CD1    1 
ATOM   3886  C CD2    . TYR A 1 247 ? -30.906 -10.376 -47.232 1.00 23.32  ? 247 TYR A CD2    1 
ATOM   3887  C CE1    . TYR A 1 247 ? -31.764 -10.080 -49.834 1.00 24.23  ? 247 TYR A CE1    1 
ATOM   3888  C CE2    . TYR A 1 247 ? -30.443 -11.231 -48.209 1.00 24.68  ? 247 TYR A CE2    1 
ATOM   3889  C CZ     . TYR A 1 247 ? -30.869 -11.077 -49.511 1.00 28.48  ? 247 TYR A CZ     1 
ATOM   3890  O OH     . TYR A 1 247 ? -30.403 -11.929 -50.493 1.00 27.54  ? 247 TYR A OH     1 
ATOM   3891  H H      . TYR A 1 247 ? -30.010 -7.339  -46.313 1.00 27.88  ? 247 TYR A H      1 
ATOM   3892  H HA     . TYR A 1 247 ? -32.323 -6.708  -47.578 1.00 31.31  ? 247 TYR A HA     1 
ATOM   3893  H HB2    . TYR A 1 247 ? -31.932 -8.701  -45.616 1.00 29.33  ? 247 TYR A HB2    1 
ATOM   3894  H HB3    . TYR A 1 247 ? -33.276 -8.486  -46.437 1.00 29.33  ? 247 TYR A HB3    1 
ATOM   3895  H HD1    . TYR A 1 247 ? -32.827 -8.557  -49.072 1.00 36.90  ? 247 TYR A HD1    1 
ATOM   3896  H HD2    . TYR A 1 247 ? -30.612 -10.482 -46.356 1.00 27.98  ? 247 TYR A HD2    1 
ATOM   3897  H HE1    . TYR A 1 247 ? -32.053 -9.978  -50.712 1.00 29.08  ? 247 TYR A HE1    1 
ATOM   3898  H HE2    . TYR A 1 247 ? -29.838 -11.903 -47.992 1.00 29.62  ? 247 TYR A HE2    1 
ATOM   3899  H HH     . TYR A 1 247 ? -29.754 -12.374 -50.200 1.00 33.04  ? 247 TYR A HH     1 
ATOM   3900  N N      . ALA A 1 248 ? -31.638 -5.131  -45.177 1.00 29.54  ? 248 ALA A N      1 
ATOM   3901  C CA     . ALA A 1 248 ? -32.034 -4.221  -44.111 1.00 26.71  ? 248 ALA A CA     1 
ATOM   3902  C C      . ALA A 1 248 ? -31.915 -2.766  -44.551 1.00 26.92  ? 248 ALA A C      1 
ATOM   3903  O O      . ALA A 1 248 ? -31.166 -2.440  -45.474 1.00 24.48  ? 248 ALA A O      1 
ATOM   3904  C CB     . ALA A 1 248 ? -31.190 -4.464  -42.868 1.00 25.76  ? 248 ALA A CB     1 
ATOM   3905  H H      . ALA A 1 248 ? -30.836 -5.004  -45.459 1.00 35.45  ? 248 ALA A H      1 
ATOM   3906  H HA     . ALA A 1 248 ? -32.960 -4.379  -43.872 1.00 32.06  ? 248 ALA A HA     1 
ATOM   3907  H HB1    . ALA A 1 248 ? -31.490 -3.871  -42.161 1.00 30.91  ? 248 ALA A HB1    1 
ATOM   3908  H HB2    . ALA A 1 248 ? -31.293 -5.388  -42.593 1.00 30.91  ? 248 ALA A HB2    1 
ATOM   3909  H HB3    . ALA A 1 248 ? -30.260 -4.285  -43.079 1.00 30.91  ? 248 ALA A HB3    1 
ATOM   3910  N N      . ASP A 1 249 ? -32.675 -1.900  -43.892 1.00 23.35  ? 249 ASP A N      1 
ATOM   3911  C CA     . ASP A 1 249 ? -32.599 -0.462  -44.145 1.00 25.20  ? 249 ASP A CA     1 
ATOM   3912  C C      . ASP A 1 249 ? -31.605 0.211   -43.209 1.00 24.12  ? 249 ASP A C      1 
ATOM   3913  O O      . ASP A 1 249 ? -31.278 1.393   -43.378 1.00 23.72  ? 249 ASP A O      1 
ATOM   3914  C CB     . ASP A 1 249 ? -33.975 0.171   -43.987 1.00 27.54  ? 249 ASP A CB     1 
ATOM   3915  C CG     . ASP A 1 249 ? -34.939 -0.303  -45.037 1.00 31.12  ? 249 ASP A CG     1 
ATOM   3916  O OD1    . ASP A 1 249 ? -34.712 0.009   -46.224 1.00 32.76  ? 249 ASP A OD1    1 
ATOM   3917  O OD2    . ASP A 1 249 ? -35.908 -0.998  -44.679 1.00 31.47  ? 249 ASP A OD2    1 
ATOM   3918  H H      . ASP A 1 249 ? -33.247 -2.119  -43.289 1.00 28.03  ? 249 ASP A H      1 
ATOM   3919  H HA     . ASP A 1 249 ? -32.305 -0.308  -45.056 1.00 30.24  ? 249 ASP A HA     1 
ATOM   3920  H HB2    . ASP A 1 249 ? -34.335 -0.064  -43.118 1.00 33.05  ? 249 ASP A HB2    1 
ATOM   3921  H HB3    . ASP A 1 249 ? -33.893 1.134   -44.065 1.00 33.05  ? 249 ASP A HB3    1 
ATOM   3922  N N      . GLY A 1 250 ? -31.129 -0.552  -42.230 1.00 23.00  ? 250 GLY A N      1 
ATOM   3923  C CA     . GLY A 1 250 ? -30.227 -0.037  -41.214 1.00 25.11  ? 250 GLY A CA     1 
ATOM   3924  C C      . GLY A 1 250 ? -30.051 -1.053  -40.102 1.00 23.19  ? 250 GLY A C      1 
ATOM   3925  O O      . GLY A 1 250 ? -30.568 -2.174  -40.169 1.00 23.77  ? 250 GLY A O      1 
ATOM   3926  H H      . GLY A 1 250 ? -31.316 -1.385  -42.129 1.00 27.60  ? 250 GLY A H      1 
ATOM   3927  H HA2    . GLY A 1 250 ? -29.361 0.154   -41.606 1.00 30.13  ? 250 GLY A HA2    1 
ATOM   3928  H HA3    . GLY A 1 250 ? -30.589 0.780   -40.838 1.00 30.13  ? 250 GLY A HA3    1 
ATOM   3929  N N      . CYS A 1 251 ? -29.319 -0.672  -39.064 1.00 22.14  ? 251 CYS A N      1 
ATOM   3930  C CA     . CYS A 1 251 ? -29.119 -1.570  -37.949 1.00 21.15  ? 251 CYS A CA     1 
ATOM   3931  C C      . CYS A 1 251 ? -28.655 -0.832  -36.707 1.00 23.85  ? 251 CYS A C      1 
ATOM   3932  O O      . CYS A 1 251 ? -28.156 0.286   -36.783 1.00 23.79  ? 251 CYS A O      1 
ATOM   3933  C CB     . CYS A 1 251 ? -28.107 -2.656  -38.318 1.00 23.03  ? 251 CYS A CB     1 
ATOM   3934  S SG     . CYS A 1 251 ? -26.357 -2.151  -38.219 1.00 28.37  ? 251 CYS A SG     1 
ATOM   3935  H H      . CYS A 1 251 ? -28.933 0.093   -38.985 1.00 26.56  ? 251 CYS A H      1 
ATOM   3936  H HA     . CYS A 1 251 ? -29.962 -2.000  -37.741 1.00 25.38  ? 251 CYS A HA     1 
ATOM   3937  H HB2    . CYS A 1 251 ? -28.228 -3.406  -37.715 1.00 27.63  ? 251 CYS A HB2    1 
ATOM   3938  H HB3    . CYS A 1 251 ? -28.276 -2.943  -39.229 1.00 27.63  ? 251 CYS A HB3    1 
ATOM   3939  H HG     . CYS A 1 251 ? -26.089 -1.443  -39.146 1.00 34.04  ? 251 CYS A HG     1 
ATOM   3940  N N      . THR A 1 252 ? -28.867 -1.462  -35.558 1.00 20.25  ? 252 THR A N      1 
ATOM   3941  C CA     . THR A 1 252 ? -28.264 -1.027  -34.311 1.00 21.37  ? 252 THR A CA     1 
ATOM   3942  C C      . THR A 1 252 ? -27.270 -2.115  -33.956 1.00 22.13  ? 252 THR A C      1 
ATOM   3943  O O      . THR A 1 252 ? -27.610 -3.292  -33.990 1.00 25.48  ? 252 THR A O      1 
ATOM   3944  C CB     . THR A 1 252 ? -29.292 -0.840  -33.184 1.00 25.16  ? 252 THR A CB     1 
ATOM   3945  O OG1    . THR A 1 252 ? -30.022 -2.056  -32.984 1.00 24.40  ? 252 THR A OG1    1 
ATOM   3946  C CG2    . THR A 1 252 ? -30.261 0.286   -33.525 1.00 25.95  ? 252 THR A CG2    1 
ATOM   3947  H H      . THR A 1 252 ? -29.366 -2.157  -35.476 1.00 24.30  ? 252 THR A H      1 
ATOM   3948  H HA     . THR A 1 252 ? -27.783 -0.194  -34.435 1.00 25.64  ? 252 THR A HA     1 
ATOM   3949  H HB     . THR A 1 252 ? -28.830 -0.606  -32.364 1.00 30.19  ? 252 THR A HB     1 
ATOM   3950  H HG1    . THR A 1 252 ? -29.502 -2.667  -32.736 1.00 29.29  ? 252 THR A HG1    1 
ATOM   3951  H HG21   . THR A 1 252 ? -30.904 0.399   -32.807 1.00 31.14  ? 252 THR A HG21   1 
ATOM   3952  H HG22   . THR A 1 252 ? -29.774 1.116   -33.646 1.00 31.14  ? 252 THR A HG22   1 
ATOM   3953  H HG23   . THR A 1 252 ? -30.737 0.077   -34.344 1.00 31.14  ? 252 THR A HG23   1 
ATOM   3954  N N      . MET A 1 253 ? -26.042 -1.723  -33.650 1.00 17.57  ? 253 MET A N      1 
ATOM   3955  C CA     . MET A 1 253 ? -24.971 -2.677  -33.380 1.00 20.44  ? 253 MET A CA     1 
ATOM   3956  C C      . MET A 1 253 ? -24.344 -2.433  -32.018 1.00 21.54  ? 253 MET A C      1 
ATOM   3957  O O      . MET A 1 253 ? -24.084 -1.288  -31.645 1.00 19.91  ? 253 MET A O      1 
ATOM   3958  C CB     . MET A 1 253 ? -23.891 -2.578  -34.455 1.00 21.32  ? 253 MET A CB     1 
ATOM   3959  C CG     . MET A 1 253 ? -22.770 -3.613  -34.317 1.00 24.94  ? 253 MET A CG     1 
ATOM   3960  S SD     . MET A 1 253 ? -23.435 -5.280  -34.328 1.00 27.98  ? 253 MET A SD     1 
ATOM   3961  C CE     . MET A 1 253 ? -21.974 -6.270  -33.989 1.00 28.98  ? 253 MET A CE     1 
ATOM   3962  H H      . MET A 1 253 ? -25.798 -0.900  -33.591 1.00 21.08  ? 253 MET A H      1 
ATOM   3963  H HA     . MET A 1 253 ? -25.329 -3.577  -33.396 1.00 24.53  ? 253 MET A HA     1 
ATOM   3964  H HB2    . MET A 1 253 ? -24.304 -2.704  -35.324 1.00 25.59  ? 253 MET A HB2    1 
ATOM   3965  H HB3    . MET A 1 253 ? -23.487 -1.697  -34.410 1.00 25.59  ? 253 MET A HB3    1 
ATOM   3966  H HG2    . MET A 1 253 ? -22.158 -3.528  -35.064 1.00 29.93  ? 253 MET A HG2    1 
ATOM   3967  H HG3    . MET A 1 253 ? -22.300 -3.475  -33.480 1.00 29.93  ? 253 MET A HG3    1 
ATOM   3968  H HE1    . MET A 1 253 ? -22.230 -7.205  -33.945 1.00 34.78  ? 253 MET A HE1    1 
ATOM   3969  H HE2    . MET A 1 253 ? -21.330 -6.136  -34.702 1.00 34.78  ? 253 MET A HE2    1 
ATOM   3970  H HE3    . MET A 1 253 ? -21.593 -5.991  -33.142 1.00 34.78  ? 253 MET A HE3    1 
ATOM   3971  N N      . SER A 1 254 ? -24.090 -3.517  -31.293 1.00 22.60  ? 254 SER A N      1 
ATOM   3972  C CA     . SER A 1 254 ? -23.265 -3.465  -30.096 1.00 21.14  ? 254 SER A CA     1 
ATOM   3973  C C      . SER A 1 254 ? -21.906 -4.068  -30.413 1.00 20.68  ? 254 SER A C      1 
ATOM   3974  O O      . SER A 1 254 ? -21.792 -5.269  -30.653 1.00 20.98  ? 254 SER A O      1 
ATOM   3975  C CB     . SER A 1 254 ? -23.925 -4.212  -28.938 1.00 24.26  ? 254 SER A CB     1 
ATOM   3976  O OG     . SER A 1 254 ? -23.035 -4.330  -27.841 1.00 23.31  ? 254 SER A OG     1 
ATOM   3977  H H      . SER A 1 254 ? -24.388 -4.302  -31.477 1.00 27.12  ? 254 SER A H      1 
ATOM   3978  H HA     . SER A 1 254 ? -23.132 -2.545  -29.822 1.00 25.37  ? 254 SER A HA     1 
ATOM   3979  H HB2    . SER A 1 254 ? -24.713 -3.722  -28.655 1.00 29.11  ? 254 SER A HB2    1 
ATOM   3980  H HB3    . SER A 1 254 ? -24.176 -5.100  -29.237 1.00 29.11  ? 254 SER A HB3    1 
ATOM   3981  H HG     . SER A 1 254 ? -22.808 -3.567  -27.572 1.00 27.97  ? 254 SER A HG     1 
ATOM   3982  N N      . GLY A 1 255 ? -20.880 -3.225  -30.422 1.00 16.84  ? 255 GLY A N      1 
ATOM   3983  C CA     . GLY A 1 255 ? -19.531 -3.680  -30.666 1.00 18.31  ? 255 GLY A CA     1 
ATOM   3984  C C      . GLY A 1 255 ? -19.067 -4.568  -29.534 1.00 18.94  ? 255 GLY A C      1 
ATOM   3985  O O      . GLY A 1 255 ? -18.208 -5.433  -29.721 1.00 18.15  ? 255 GLY A O      1 
ATOM   3986  H H      . GLY A 1 255 ? -20.946 -2.378  -30.288 1.00 20.20  ? 255 GLY A H      1 
ATOM   3987  H HA2    . GLY A 1 255 ? -19.508 -4.186  -31.492 1.00 21.98  ? 255 GLY A HA2    1 
ATOM   3988  H HA3    . GLY A 1 255 ? -18.931 -2.921  -30.741 1.00 21.98  ? 255 GLY A HA3    1 
ATOM   3989  N N      . LYS A 1 256 ? -19.657 -4.350  -28.357 1.00 16.81  ? 256 LYS A N      1 
ATOM   3990  C CA     . LYS A 1 256 ? -19.347 -5.117  -27.151 1.00 22.45  ? 256 LYS A CA     1 
ATOM   3991  C C      . LYS A 1 256 ? -19.596 -6.602  -27.302 1.00 19.58  ? 256 LYS A C      1 
ATOM   3992  O O      . LYS A 1 256 ? -19.106 -7.400  -26.499 1.00 17.85  ? 256 LYS A O      1 
ATOM   3993  C CB     . LYS A 1 256 ? -20.177 -4.601  -25.983 1.00 18.48  ? 256 LYS A CB     1 
ATOM   3994  C CG     . LYS A 1 256 ? -19.963 -3.136  -25.704 1.00 19.56  ? 256 LYS A CG     1 
ATOM   3995  C CD     . LYS A 1 256 ? -20.891 -2.669  -24.591 1.00 21.24  ? 256 LYS A CD     1 
ATOM   3996  C CE     . LYS A 1 256 ? -20.521 -3.256  -23.253 1.00 21.08  ? 256 LYS A CE     1 
ATOM   3997  N NZ     . LYS A 1 256 ? -21.334 -2.614  -22.187 1.00 23.02  ? 256 LYS A NZ     1 
ATOM   3998  H H      . LYS A 1 256 ? -20.256 -3.748  -28.229 1.00 20.17  ? 256 LYS A H      1 
ATOM   3999  H HA     . LYS A 1 256 ? -18.411 -4.992  -26.931 1.00 26.94  ? 256 LYS A HA     1 
ATOM   4000  H HB2    . LYS A 1 256 ? -21.117 -4.734  -26.181 1.00 22.18  ? 256 LYS A HB2    1 
ATOM   4001  H HB3    . LYS A 1 256 ? -19.934 -5.096  -25.186 1.00 22.18  ? 256 LYS A HB3    1 
ATOM   4002  H HG2    . LYS A 1 256 ? -19.047 -2.995  -25.420 1.00 23.47  ? 256 LYS A HG2    1 
ATOM   4003  H HG3    . LYS A 1 256 ? -20.156 -2.618  -26.500 1.00 23.47  ? 256 LYS A HG3    1 
ATOM   4004  H HD2    . LYS A 1 256 ? -20.841 -1.703  -24.520 1.00 25.48  ? 256 LYS A HD2    1 
ATOM   4005  H HD3    . LYS A 1 256 ? -21.798 -2.941  -24.799 1.00 25.48  ? 256 LYS A HD3    1 
ATOM   4006  H HE2    . LYS A 1 256 ? -20.706 -4.208  -23.250 1.00 25.30  ? 256 LYS A HE2    1 
ATOM   4007  H HE3    . LYS A 1 256 ? -19.583 -3.089  -23.071 1.00 25.30  ? 256 LYS A HE3    1 
ATOM   4008  H HZ1    . LYS A 1 256 ? -21.181 -1.737  -22.174 1.00 27.63  ? 256 LYS A HZ1    1 
ATOM   4009  H HZ2    . LYS A 1 256 ? -22.200 -2.754  -22.339 1.00 27.63  ? 256 LYS A HZ2    1 
ATOM   4010  H HZ3    . LYS A 1 256 ? -21.120 -2.956  -21.394 1.00 27.63  ? 256 LYS A HZ3    1 
HETATM 4011  N N1     . LLP A 1 257 ? -30.042 -6.240  -28.323 1.00 29.96  ? 257 LLP A N1     1 
HETATM 4012  C C2     . LLP A 1 257 ? -29.468 -7.438  -28.219 1.00 34.04  ? 257 LLP A C2     1 
HETATM 4013  C "C2'"  . LLP A 1 257 ? -30.083 -8.662  -28.964 1.00 38.33  ? 257 LLP A "C2'"  1 
HETATM 4014  C C3     . LLP A 1 257 ? -28.296 -7.599  -27.427 1.00 34.34  ? 257 LLP A C3     1 
HETATM 4015  O O3     . LLP A 1 257 ? -27.706 -8.867  -27.329 1.00 41.40  ? 257 LLP A O3     1 
HETATM 4016  C C4     . LLP A 1 257 ? -27.742 -6.521  -26.765 1.00 28.42  ? 257 LLP A C4     1 
HETATM 4017  C "C4'"  . LLP A 1 257 ? -26.411 -6.721  -25.871 1.00 27.55  ? 257 LLP A "C4'"  1 
HETATM 4018  C C5     . LLP A 1 257 ? -28.332 -5.295  -26.880 1.00 25.89  ? 257 LLP A C5     1 
HETATM 4019  C C6     . LLP A 1 257 ? -29.487 -5.149  -27.650 1.00 30.21  ? 257 LLP A C6     1 
HETATM 4020  C "C5'"  . LLP A 1 257 ? -27.797 -4.021  -26.156 1.00 26.46  ? 257 LLP A "C5'"  1 
HETATM 4021  O OP4    . LLP A 1 257 ? -26.523 -3.654  -26.619 1.00 22.48  ? 257 LLP A OP4    1 
HETATM 4022  P P      . LLP A 1 257 ? -25.593 -2.967  -25.581 1.00 22.48  ? 257 LLP A P      1 
HETATM 4023  O OP1    . LLP A 1 257 ? -24.260 -2.665  -26.274 1.00 23.07  ? 257 LLP A OP1    1 
HETATM 4024  O OP2    . LLP A 1 257 ? -25.398 -3.863  -24.417 1.00 21.84  ? 257 LLP A OP2    1 
HETATM 4025  O OP3    . LLP A 1 257 ? -26.241 -1.696  -25.113 1.00 19.99  ? 257 LLP A OP3    1 
HETATM 4026  N N      . LLP A 1 257 ? -20.383 -6.968  -28.311 1.00 16.75  ? 257 LLP A N      1 
HETATM 4027  C CA     . LLP A 1 257 ? -20.633 -8.391  -28.611 1.00 19.33  ? 257 LLP A CA     1 
HETATM 4028  C CB     . LLP A 1 257 ? -22.101 -8.620  -28.935 1.00 17.38  ? 257 LLP A CB     1 
HETATM 4029  C CG     . LLP A 1 257 ? -22.935 -8.845  -27.660 1.00 23.25  ? 257 LLP A CG     1 
HETATM 4030  C CD     . LLP A 1 257 ? -23.221 -7.535  -26.908 1.00 24.79  ? 257 LLP A CD     1 
HETATM 4031  C CE     . LLP A 1 257 ? -24.272 -7.764  -25.787 1.00 27.15  ? 257 LLP A CE     1 
HETATM 4032  N NZ     . LLP A 1 257 ? -25.625 -7.813  -26.361 1.00 30.28  ? 257 LLP A NZ     1 
HETATM 4033  C C      . LLP A 1 257 ? -19.702 -8.757  -29.721 1.00 18.19  ? 257 LLP A C      1 
HETATM 4034  O O      . LLP A 1 257 ? -18.519 -8.962  -29.461 1.00 17.92  ? 257 LLP A O      1 
HETATM 4035  H "H2'1" . LLP A 1 257 ? -29.489 -8.935  -29.681 1.00 45.99  ? 257 LLP A "H2'1" 1 
HETATM 4036  H "H2'2" . LLP A 1 257 ? -30.946 -8.419  -29.335 1.00 45.99  ? 257 LLP A "H2'2" 1 
HETATM 4037  H "H2'3" . LLP A 1 257 ? -30.194 -9.395  -28.339 1.00 45.99  ? 257 LLP A "H2'3" 1 
HETATM 4038  H HO3    . LLP A 1 257 ? -27.915 -9.221  -26.585 1.00 49.68  ? 257 LLP A HO3    1 
HETATM 4039  H "H4'1" . LLP A 1 257 ? -26.668 -6.903  -24.953 1.00 33.06  ? 257 LLP A "H4'1" 1 
HETATM 4040  H H6     . LLP A 1 257 ? -29.878 -4.318  -27.713 1.00 36.25  ? 257 LLP A H6     1 
HETATM 4041  H "H5'1" . LLP A 1 257 ? -27.754 -4.197  -25.203 1.00 31.75  ? 257 LLP A "H5'1" 1 
HETATM 4042  H "H5'2" . LLP A 1 257 ? -28.411 -3.287  -26.313 1.00 31.75  ? 257 LLP A "H5'2" 1 
HETATM 4043  H HA     . LLP A 1 257 ? -20.408 -8.927  -27.835 1.00 23.20  ? 257 LLP A HA     1 
HETATM 4044  H HB2    . LLP A 1 257 ? -22.185 -9.399  -29.506 1.00 20.86  ? 257 LLP A HB2    1 
HETATM 4045  H HB3    . LLP A 1 257 ? -22.445 -7.843  -29.403 1.00 20.86  ? 257 LLP A HB3    1 
HETATM 4046  H HG2    . LLP A 1 257 ? -22.456 -9.448  -27.070 1.00 27.91  ? 257 LLP A HG2    1 
HETATM 4047  H HG3    . LLP A 1 257 ? -23.779 -9.253  -27.907 1.00 27.91  ? 257 LLP A HG3    1 
HETATM 4048  H HD2    . LLP A 1 257 ? -23.559 -6.875  -27.534 1.00 29.75  ? 257 LLP A HD2    1 
HETATM 4049  H HD3    . LLP A 1 257 ? -22.398 -7.208  -26.512 1.00 29.75  ? 257 LLP A HD3    1 
HETATM 4050  H HE2    . LLP A 1 257 ? -24.215 -7.046  -25.138 1.00 32.59  ? 257 LLP A HE2    1 
HETATM 4051  H HE3    . LLP A 1 257 ? -24.086 -8.608  -25.347 1.00 32.59  ? 257 LLP A HE3    1 
ATOM   4052  N N      . ASP A 1 258 ? -20.177 -8.805  -30.963 1.00 19.60  ? 258 ASP A N      1 
ATOM   4053  C CA     . ASP A 1 258 ? -19.383 -9.449  -32.009 1.00 19.94  ? 258 ASP A CA     1 
ATOM   4054  C C      . ASP A 1 258 ? -18.259 -8.589  -32.634 1.00 20.24  ? 258 ASP A C      1 
ATOM   4055  O O      . ASP A 1 258 ? -17.542 -9.102  -33.483 1.00 20.15  ? 258 ASP A O      1 
ATOM   4056  C CB     . ASP A 1 258 ? -20.305 -9.968  -33.136 1.00 22.38  ? 258 ASP A CB     1 
ATOM   4057  C CG     . ASP A 1 258 ? -20.640 -11.471 -33.008 1.00 23.86  ? 258 ASP A CG     1 
ATOM   4058  O OD1    . ASP A 1 258 ? -20.014 -12.192 -32.204 1.00 21.75  ? 258 ASP A OD1    1 
ATOM   4059  O OD2    . ASP A 1 258 ? -21.525 -11.947 -33.750 1.00 22.61  ? 258 ASP A OD2    1 
ATOM   4060  H H      . ASP A 1 258 ? -20.931 -8.482  -31.223 1.00 23.51  ? 258 ASP A H      1 
ATOM   4061  H HA     . ASP A 1 258 ? -18.940 -10.212 -31.610 1.00 23.93  ? 258 ASP A HA     1 
ATOM   4062  H HB2    . ASP A 1 258 ? -21.140 -9.475  -33.111 1.00 26.86  ? 258 ASP A HB2    1 
ATOM   4063  H HB3    . ASP A 1 258 ? -19.870 -9.833  -33.992 1.00 26.86  ? 258 ASP A HB3    1 
ATOM   4064  N N      . CYS A 1 259 ? -18.066 -7.328  -32.224 1.00 18.24  ? 259 CYS A N      1 
ATOM   4065  C CA     . CYS A 1 259 ? -16.899 -6.565  -32.702 1.00 19.27  ? 259 CYS A CA     1 
ATOM   4066  C C      . CYS A 1 259 ? -15.689 -6.689  -31.778 1.00 16.97  ? 259 CYS A C      1 
ATOM   4067  O O      . CYS A 1 259 ? -14.721 -5.944  -31.929 1.00 17.76  ? 259 CYS A O      1 
ATOM   4068  C CB     . CYS A 1 259 ? -17.221 -5.081  -32.872 1.00 20.55  ? 259 CYS A CB     1 
ATOM   4069  S SG     . CYS A 1 259 ? -18.532 -4.723  -34.058 1.00 22.22  ? 259 CYS A SG     1 
ATOM   4070  H H      . CYS A 1 259 ? -18.580 -6.900  -31.684 1.00 21.89  ? 259 CYS A H      1 
ATOM   4071  H HA     . CYS A 1 259 ? -16.635 -6.897  -33.574 1.00 23.12  ? 259 CYS A HA     1 
ATOM   4072  H HB2    . CYS A 1 259 ? -17.479 -4.717  -32.014 1.00 24.66  ? 259 CYS A HB2    1 
ATOM   4073  H HB3    . CYS A 1 259 ? -16.423 -4.627  -33.186 1.00 24.66  ? 259 CYS A HB3    1 
ATOM   4074  H HG     . CYS A 1 259 ? -18.699 -3.536  -34.110 1.00 26.66  ? 259 CYS A HG     1 
ATOM   4075  N N      . LEU A 1 260 ? -15.745 -7.610  -30.821 1.00 18.17  ? 260 LEU A N      1 
ATOM   4076  C CA     . LEU A 1 260 ? -14.565 -7.981  -30.030 1.00 15.09  ? 260 LEU A CA     1 
ATOM   4077  C C      . LEU A 1 260 ? -13.961 -6.796  -29.258 1.00 16.39  ? 260 LEU A C      1 
ATOM   4078  O O      . LEU A 1 260 ? -12.738 -6.643  -29.178 1.00 17.41  ? 260 LEU A O      1 
ATOM   4079  C CB     . LEU A 1 260 ? -13.502 -8.611  -30.948 1.00 16.61  ? 260 LEU A CB     1 
ATOM   4080  C CG     . LEU A 1 260 ? -13.865 -9.987  -31.500 1.00 17.90  ? 260 LEU A CG     1 
ATOM   4081  C CD1    . LEU A 1 260 ? -12.995 -10.331 -32.701 1.00 17.84  ? 260 LEU A CD1    1 
ATOM   4082  C CD2    . LEU A 1 260 ? -13.703 -11.032 -30.402 1.00 16.64  ? 260 LEU A CD2    1 
ATOM   4083  H H      . LEU A 1 260 ? -16.457 -8.041  -30.604 1.00 21.80  ? 260 LEU A H      1 
ATOM   4084  H HA     . LEU A 1 260 ? -14.827 -8.651  -29.379 1.00 18.11  ? 260 LEU A HA     1 
ATOM   4085  H HB2    . LEU A 1 260 ? -13.346 -8.024  -31.703 1.00 19.93  ? 260 LEU A HB2    1 
ATOM   4086  H HB3    . LEU A 1 260 ? -12.679 -8.717  -30.446 1.00 19.93  ? 260 LEU A HB3    1 
ATOM   4087  H HG     . LEU A 1 260 ? -14.792 -9.985  -31.785 1.00 21.48  ? 260 LEU A HG     1 
ATOM   4088  H HD11   . LEU A 1 260 ? -13.241 -11.211 -33.027 1.00 21.41  ? 260 LEU A HD11   1 
ATOM   4089  H HD12   . LEU A 1 260 ? -13.139 -9.669  -33.395 1.00 21.41  ? 260 LEU A HD12   1 
ATOM   4090  H HD13   . LEU A 1 260 ? -12.064 -10.327 -32.428 1.00 21.41  ? 260 LEU A HD13   1 
ATOM   4091  H HD21   . LEU A 1 260 ? -13.799 -11.915 -30.790 1.00 19.97  ? 260 LEU A HD21   1 
ATOM   4092  H HD22   . LEU A 1 260 ? -12.822 -10.940 -30.006 1.00 19.97  ? 260 LEU A HD22   1 
ATOM   4093  H HD23   . LEU A 1 260 ? -14.385 -10.890 -29.727 1.00 19.97  ? 260 LEU A HD23   1 
ATOM   4094  N N      . VAL A 1 261 ? -14.825 -5.964  -28.688 1.00 15.60  ? 261 VAL A N      1 
ATOM   4095  C CA     . VAL A 1 261 ? -14.371 -4.835  -27.886 1.00 15.66  ? 261 VAL A CA     1 
ATOM   4096  C C      . VAL A 1 261 ? -15.074 -4.788  -26.529 1.00 18.30  ? 261 VAL A C      1 
ATOM   4097  O O      . VAL A 1 261 ? -15.990 -5.567  -26.261 1.00 18.64  ? 261 VAL A O      1 
ATOM   4098  C CB     . VAL A 1 261 ? -14.578 -3.497  -28.633 1.00 17.32  ? 261 VAL A CB     1 
ATOM   4099  C CG1    . VAL A 1 261 ? -13.590 -3.387  -29.784 1.00 14.35  ? 261 VAL A CG1    1 
ATOM   4100  C CG2    . VAL A 1 261 ? -16.012 -3.369  -29.140 1.00 15.58  ? 261 VAL A CG2    1 
ATOM   4101  H H      . VAL A 1 261 ? -15.680 -6.031  -28.750 1.00 18.73  ? 261 VAL A H      1 
ATOM   4102  H HA     . VAL A 1 261 ? -13.422 -4.923  -27.709 1.00 18.79  ? 261 VAL A HA     1 
ATOM   4103  H HB     . VAL A 1 261 ? -14.410 -2.764  -28.022 1.00 20.78  ? 261 VAL A HB     1 
ATOM   4104  H HG11   . VAL A 1 261 ? -13.647 -2.496  -30.163 1.00 17.22  ? 261 VAL A HG11   1 
ATOM   4105  H HG12   . VAL A 1 261 ? -12.694 -3.546  -29.447 1.00 17.22  ? 261 VAL A HG12   1 
ATOM   4106  H HG13   . VAL A 1 261 ? -13.813 -4.049  -30.456 1.00 17.22  ? 261 VAL A HG13   1 
ATOM   4107  H HG21   . VAL A 1 261 ? -16.158 -2.459  -29.442 1.00 18.70  ? 261 VAL A HG21   1 
ATOM   4108  H HG22   . VAL A 1 261 ? -16.140 -3.985  -29.877 1.00 18.70  ? 261 VAL A HG22   1 
ATOM   4109  H HG23   . VAL A 1 261 ? -16.625 -3.579  -28.419 1.00 18.70  ? 261 VAL A HG23   1 
ATOM   4110  N N      . ASN A 1 262 ? -14.604 -3.891  -25.667 1.00 14.83  ? 262 ASN A N      1 
ATOM   4111  C CA     . ASN A 1 262 ? -15.099 -3.804  -24.302 1.00 15.66  ? 262 ASN A CA     1 
ATOM   4112  C C      . ASN A 1 262 ? -16.128 -2.680  -24.139 1.00 18.16  ? 262 ASN A C      1 
ATOM   4113  O O      . ASN A 1 262 ? -16.757 -2.550  -23.093 1.00 17.40  ? 262 ASN A O      1 
ATOM   4114  C CB     . ASN A 1 262 ? -13.925 -3.599  -23.345 1.00 14.86  ? 262 ASN A CB     1 
ATOM   4115  C CG     . ASN A 1 262 ? -12.839 -4.651  -23.519 1.00 17.07  ? 262 ASN A CG     1 
ATOM   4116  O OD1    . ASN A 1 262 ? -11.704 -4.342  -23.886 1.00 17.71  ? 262 ASN A OD1    1 
ATOM   4117  N ND2    . ASN A 1 262 ? -13.193 -5.912  -23.272 1.00 17.37  ? 262 ASN A ND2    1 
ATOM   4118  H H      . ASN A 1 262 ? -13.992 -3.316  -25.853 1.00 17.79  ? 262 ASN A H      1 
ATOM   4119  H HA     . ASN A 1 262 ? -15.529 -4.638  -24.062 1.00 18.80  ? 262 ASN A HA     1 
ATOM   4120  H HB2    . ASN A 1 262 ? -13.530 -2.729  -23.511 1.00 17.84  ? 262 ASN A HB2    1 
ATOM   4121  H HB3    . ASN A 1 262 ? -14.248 -3.649  -22.432 1.00 17.84  ? 262 ASN A HB3    1 
ATOM   4122  H HD21   . ASN A 1 262 ? -12.617 -6.545  -23.356 1.00 20.84  ? 262 ASN A HD21   1 
ATOM   4123  H HD22   . ASN A 1 262 ? -13.998 -6.093  -23.029 1.00 20.84  ? 262 ASN A HD22   1 
ATOM   4124  N N      . ILE A 1 263 ? -16.284 -1.880  -25.187 1.00 15.21  ? 263 ILE A N      1 
ATOM   4125  C CA     . ILE A 1 263 ? -17.230 -0.764  -25.211 1.00 16.17  ? 263 ILE A CA     1 
ATOM   4126  C C      . ILE A 1 263 ? -17.363 -0.334  -26.674 1.00 16.40  ? 263 ILE A C      1 
ATOM   4127  O O      . ILE A 1 263 ? -16.448 -0.549  -27.458 1.00 18.02  ? 263 ILE A O      1 
ATOM   4128  C CB     . ILE A 1 263 ? -16.769 0.426   -24.322 1.00 21.57  ? 263 ILE A CB     1 
ATOM   4129  C CG1    . ILE A 1 263 ? -17.909 1.438   -24.099 1.00 22.18  ? 263 ILE A CG1    1 
ATOM   4130  C CG2    . ILE A 1 263 ? -15.557 1.138   -24.929 1.00 17.86  ? 263 ILE A CG2    1 
ATOM   4131  C CD1    . ILE A 1 263 ? -19.084 0.873   -23.308 1.00 22.92  ? 263 ILE A CD1    1 
ATOM   4132  H H      . ILE A 1 263 ? -15.842 -1.960  -25.920 1.00 18.25  ? 263 ILE A H      1 
ATOM   4133  H HA     . ILE A 1 263 ? -18.095 -1.069  -24.899 1.00 19.40  ? 263 ILE A HA     1 
ATOM   4134  H HB     . ILE A 1 263 ? -16.508 0.072   -23.458 1.00 25.88  ? 263 ILE A HB     1 
ATOM   4135  H HG12   . ILE A 1 263 ? -17.559 2.197   -23.607 1.00 26.61  ? 263 ILE A HG12   1 
ATOM   4136  H HG13   . ILE A 1 263 ? -18.243 1.732   -24.960 1.00 26.61  ? 263 ILE A HG13   1 
ATOM   4137  H HG21   . ILE A 1 263 ? -15.153 1.704   -24.253 1.00 21.43  ? 263 ILE A HG21   1 
ATOM   4138  H HG22   . ILE A 1 263 ? -14.918 0.472   -25.228 1.00 21.43  ? 263 ILE A HG22   1 
ATOM   4139  H HG23   . ILE A 1 263 ? -15.849 1.678   -25.680 1.00 21.43  ? 263 ILE A HG23   1 
ATOM   4140  H HD11   . ILE A 1 263 ? -19.695 1.595   -23.094 1.00 27.50  ? 263 ILE A HD11   1 
ATOM   4141  H HD12   . ILE A 1 263 ? -19.539 0.207   -23.845 1.00 27.50  ? 263 ILE A HD12   1 
ATOM   4142  H HD13   . ILE A 1 263 ? -18.750 0.470   -22.491 1.00 27.50  ? 263 ILE A HD13   1 
ATOM   4143  N N      . GLY A 1 264 ? -18.499 0.251   -27.041 1.00 16.69  ? 264 GLY A N      1 
ATOM   4144  C CA     . GLY A 1 264 ? -18.715 0.725   -28.400 1.00 19.34  ? 264 GLY A CA     1 
ATOM   4145  C C      . GLY A 1 264 ? -19.953 0.155   -29.064 1.00 17.84  ? 264 GLY A C      1 
ATOM   4146  O O      . GLY A 1 264 ? -20.372 -0.977  -28.792 1.00 17.94  ? 264 GLY A O      1 
ATOM   4147  H H      . GLY A 1 264 ? -19.166 0.386   -26.515 1.00 20.02  ? 264 GLY A H      1 
ATOM   4148  H HA2    . GLY A 1 264 ? -18.808 1.687   -28.390 1.00 23.21  ? 264 GLY A HA2    1 
ATOM   4149  H HA3    . GLY A 1 264 ? -17.953 0.505   -28.957 1.00 23.21  ? 264 GLY A HA3    1 
ATOM   4150  N N      . GLY A 1 265 ? -20.538 0.959   -29.941 1.00 18.41  ? 265 GLY A N      1 
ATOM   4151  C CA     . GLY A 1 265 ? -21.647 0.536   -30.771 1.00 19.38  ? 265 GLY A CA     1 
ATOM   4152  C C      . GLY A 1 265 ? -21.824 1.529   -31.898 1.00 18.42  ? 265 GLY A C      1 
ATOM   4153  O O      . GLY A 1 265 ? -21.058 2.486   -32.018 1.00 17.11  ? 265 GLY A O      1 
ATOM   4154  H H      . GLY A 1 265 ? -20.301 1.775   -30.074 1.00 22.09  ? 265 GLY A H      1 
ATOM   4155  H HA2    . GLY A 1 265 ? -21.470 -0.341  -31.145 1.00 23.25  ? 265 GLY A HA2    1 
ATOM   4156  H HA3    . GLY A 1 265 ? -22.462 0.500   -30.247 1.00 23.25  ? 265 GLY A HA3    1 
ATOM   4157  N N      . PHE A 1 266 ? -22.828 1.304   -32.734 1.00 15.98  ? 266 PHE A N      1 
ATOM   4158  C CA     . PHE A 1 266 ? -23.162 2.274   -33.760 1.00 17.87  ? 266 PHE A CA     1 
ATOM   4159  C C      . PHE A 1 266 ? -24.541 2.033   -34.359 1.00 19.39  ? 266 PHE A C      1 
ATOM   4160  O O      . PHE A 1 266 ? -25.129 0.949   -34.233 1.00 19.30  ? 266 PHE A O      1 
ATOM   4161  C CB     . PHE A 1 266 ? -22.096 2.298   -34.873 1.00 17.21  ? 266 PHE A CB     1 
ATOM   4162  C CG     . PHE A 1 266 ? -21.733 0.945   -35.431 1.00 17.24  ? 266 PHE A CG     1 
ATOM   4163  C CD1    . PHE A 1 266 ? -22.465 0.389   -36.461 1.00 19.10  ? 266 PHE A CD1    1 
ATOM   4164  C CD2    . PHE A 1 266 ? -20.633 0.256   -34.951 1.00 16.26  ? 266 PHE A CD2    1 
ATOM   4165  C CE1    . PHE A 1 266 ? -22.122 -0.849  -36.991 1.00 19.94  ? 266 PHE A CE1    1 
ATOM   4166  C CE2    . PHE A 1 266 ? -20.281 -0.969  -35.472 1.00 18.26  ? 266 PHE A CE2    1 
ATOM   4167  C CZ     . PHE A 1 266 ? -21.026 -1.522  -36.500 1.00 17.48  ? 266 PHE A CZ     1 
ATOM   4168  H H      . PHE A 1 266 ? -23.327 0.603   -32.727 1.00 19.18  ? 266 PHE A H      1 
ATOM   4169  H HA     . PHE A 1 266 ? -23.175 3.155   -33.354 1.00 21.44  ? 266 PHE A HA     1 
ATOM   4170  H HB2    . PHE A 1 266 ? -22.430 2.836   -35.608 1.00 20.65  ? 266 PHE A HB2    1 
ATOM   4171  H HB3    . PHE A 1 266 ? -21.286 2.698   -34.521 1.00 20.65  ? 266 PHE A HB3    1 
ATOM   4172  H HD1    . PHE A 1 266 ? -23.202 0.845   -36.796 1.00 22.93  ? 266 PHE A HD1    1 
ATOM   4173  H HD2    . PHE A 1 266 ? -20.126 0.624   -34.264 1.00 19.52  ? 266 PHE A HD2    1 
ATOM   4174  H HE1    . PHE A 1 266 ? -22.626 -1.217  -37.681 1.00 23.92  ? 266 PHE A HE1    1 
ATOM   4175  H HE2    . PHE A 1 266 ? -19.543 -1.424  -35.135 1.00 21.91  ? 266 PHE A HE2    1 
ATOM   4176  H HZ     . PHE A 1 266 ? -20.795 -2.353  -36.848 1.00 20.97  ? 266 PHE A HZ     1 
ATOM   4177  N N      . LEU A 1 267 ? -25.045 3.095   -34.973 1.00 19.06  ? 267 LEU A N      1 
ATOM   4178  C CA     . LEU A 1 267 ? -26.273 3.080   -35.755 1.00 18.96  ? 267 LEU A CA     1 
ATOM   4179  C C      . LEU A 1 267 ? -25.934 3.203   -37.236 1.00 18.45  ? 267 LEU A C      1 
ATOM   4180  O O      . LEU A 1 267 ? -25.212 4.124   -37.623 1.00 21.97  ? 267 LEU A O      1 
ATOM   4181  C CB     . LEU A 1 267 ? -27.182 4.235   -35.327 1.00 19.00  ? 267 LEU A CB     1 
ATOM   4182  C CG     . LEU A 1 267 ? -28.448 4.461   -36.156 1.00 21.47  ? 267 LEU A CG     1 
ATOM   4183  C CD1    . LEU A 1 267 ? -29.450 3.327   -35.950 1.00 25.23  ? 267 LEU A CD1    1 
ATOM   4184  C CD2    . LEU A 1 267 ? -29.072 5.787   -35.816 1.00 26.83  ? 267 LEU A CD2    1 
ATOM   4185  H H      . LEU A 1 267 ? -24.675 3.871   -34.949 1.00 22.87  ? 267 LEU A H      1 
ATOM   4186  H HA     . LEU A 1 267 ? -26.747 2.246   -35.614 1.00 22.75  ? 267 LEU A HA     1 
ATOM   4187  H HB2    . LEU A 1 267 ? -27.463 4.075   -34.413 1.00 22.80  ? 267 LEU A HB2    1 
ATOM   4188  H HB3    . LEU A 1 267 ? -26.666 5.055   -35.364 1.00 22.80  ? 267 LEU A HB3    1 
ATOM   4189  H HG     . LEU A 1 267 ? -28.216 4.483   -37.097 1.00 25.76  ? 267 LEU A HG     1 
ATOM   4190  H HD11   . LEU A 1 267 ? -30.296 3.578   -36.352 1.00 30.28  ? 267 LEU A HD11   1 
ATOM   4191  H HD12   . LEU A 1 267 ? -29.109 2.525   -36.373 1.00 30.28  ? 267 LEU A HD12   1 
ATOM   4192  H HD13   . LEU A 1 267 ? -29.567 3.178   -34.999 1.00 30.28  ? 267 LEU A HD13   1 
ATOM   4193  H HD21   . LEU A 1 267 ? -29.871 5.907   -36.353 1.00 32.20  ? 267 LEU A HD21   1 
ATOM   4194  H HD22   . LEU A 1 267 ? -29.302 5.795   -34.874 1.00 32.20  ? 267 LEU A HD22   1 
ATOM   4195  H HD23   . LEU A 1 267 ? -28.435 6.493   -36.007 1.00 32.20  ? 267 LEU A HD23   1 
ATOM   4196  N N      . CYS A 1 268 ? -26.445 2.290   -38.060 1.00 19.33  ? 268 CYS A N      1 
ATOM   4197  C CA     . CYS A 1 268 ? -26.319 2.416   -39.521 1.00 17.45  ? 268 CYS A CA     1 
ATOM   4198  C C      . CYS A 1 268 ? -27.661 2.627   -40.182 1.00 22.32  ? 268 CYS A C      1 
ATOM   4199  O O      . CYS A 1 268 ? -28.676 2.102   -39.724 1.00 23.06  ? 268 CYS A O      1 
ATOM   4200  C CB     . CYS A 1 268 ? -25.711 1.180   -40.166 1.00 24.93  ? 268 CYS A CB     1 
ATOM   4201  S SG     . CYS A 1 268 ? -24.125 0.688   -39.572 1.00 29.23  ? 268 CYS A SG     1 
ATOM   4202  H H      . CYS A 1 268 ? -26.870 1.587   -37.803 1.00 23.20  ? 268 CYS A H      1 
ATOM   4203  H HA     . CYS A 1 268 ? -25.757 3.173   -39.738 1.00 20.94  ? 268 CYS A HA     1 
ATOM   4204  H HB2    . CYS A 1 268 ? -26.322 0.441   -40.037 1.00 29.92  ? 268 CYS A HB2    1 
ATOM   4205  H HB3    . CYS A 1 268 ? -25.618 1.353   -41.115 1.00 29.92  ? 268 CYS A HB3    1 
ATOM   4206  H HG     . CYS A 1 268 ? -24.283 0.291   -38.452 1.00 35.07  ? 268 CYS A HG     1 
ATOM   4207  N N      . MET A 1 269 ? -27.648 3.357   -41.290 1.00 24.94  ? 269 MET A N      1 
ATOM   4208  C CA     . MET A 1 269 ? -28.840 3.505   -42.107 1.00 28.40  ? 269 MET A CA     1 
ATOM   4209  C C      . MET A 1 269 ? -28.452 3.900   -43.525 1.00 28.21  ? 269 MET A C      1 
ATOM   4210  O O      . MET A 1 269 ? -27.365 4.438   -43.758 1.00 23.80  ? 269 MET A O      1 
ATOM   4211  C CB     . MET A 1 269 ? -29.791 4.544   -41.503 1.00 28.35  ? 269 MET A CB     1 
ATOM   4212  C CG     . MET A 1 269 ? -29.340 5.991   -41.663 1.00 30.87  ? 269 MET A CG     1 
ATOM   4213  S SD     . MET A 1 269 ? -29.014 6.825   -40.113 1.00 48.71  ? 269 MET A SD     1 
ATOM   4214  C CE     . MET A 1 269 ? -27.357 6.247   -39.774 1.00 38.91  ? 269 MET A CE     1 
ATOM   4215  H H      . MET A 1 269 ? -26.960 3.777   -41.590 1.00 29.92  ? 269 MET A H      1 
ATOM   4216  H HA     . MET A 1 269 ? -29.308 2.656   -42.137 1.00 34.07  ? 269 MET A HA     1 
ATOM   4217  H HB2    . MET A 1 269 ? -30.657 4.457   -41.932 1.00 34.02  ? 269 MET A HB2    1 
ATOM   4218  H HB3    . MET A 1 269 ? -29.879 4.368   -40.553 1.00 34.02  ? 269 MET A HB3    1 
ATOM   4219  H HG2    . MET A 1 269 ? -28.521 6.029   -42.177 1.00 37.04  ? 269 MET A HG2    1 
ATOM   4220  H HG3    . MET A 1 269 ? -30.037 6.485   -42.122 1.00 37.04  ? 269 MET A HG3    1 
ATOM   4221  H HE1    . MET A 1 269 ? -27.386 5.295   -39.595 1.00 46.69  ? 269 MET A HE1    1 
ATOM   4222  H HE2    . MET A 1 269 ? -26.796 6.424   -40.545 1.00 46.69  ? 269 MET A HE2    1 
ATOM   4223  H HE3    . MET A 1 269 ? -27.014 6.717   -38.999 1.00 46.69  ? 269 MET A HE3    1 
ATOM   4224  N N      . ASN A 1 270 ? -29.349 3.627   -44.467 1.00 24.79  ? 270 ASN A N      1 
ATOM   4225  C CA     . ASN A 1 270 ? -29.141 4.015   -45.857 1.00 26.46  ? 270 ASN A CA     1 
ATOM   4226  C C      . ASN A 1 270 ? -29.790 5.355   -46.208 1.00 26.88  ? 270 ASN A C      1 
ATOM   4227  O O      . ASN A 1 270 ? -29.320 6.055   -47.099 1.00 31.41  ? 270 ASN A O      1 
ATOM   4228  C CB     . ASN A 1 270 ? -29.680 2.931   -46.779 1.00 27.83  ? 270 ASN A CB     1 
ATOM   4229  C CG     . ASN A 1 270 ? -28.869 1.657   -46.705 1.00 27.86  ? 270 ASN A CG     1 
ATOM   4230  O OD1    . ASN A 1 270 ? -27.645 1.695   -46.549 1.00 29.84  ? 270 ASN A OD1    1 
ATOM   4231  N ND2    . ASN A 1 270 ? -29.546 0.517   -46.807 1.00 28.50  ? 270 ASN A ND2    1 
ATOM   4232  H H      . ASN A 1 270 ? -30.091 3.215   -44.326 1.00 29.75  ? 270 ASN A H      1 
ATOM   4233  H HA     . ASN A 1 270 ? -28.190 4.098   -46.027 1.00 31.75  ? 270 ASN A HA     1 
ATOM   4234  H HB2    . ASN A 1 270 ? -30.592 2.723   -46.524 1.00 33.39  ? 270 ASN A HB2    1 
ATOM   4235  H HB3    . ASN A 1 270 ? -29.655 3.251   -47.694 1.00 33.39  ? 270 ASN A HB3    1 
ATOM   4236  H HD21   . ASN A 1 270 ? -29.130 -0.235  -46.771 1.00 34.19  ? 270 ASN A HD21   1 
ATOM   4237  H HD22   . ASN A 1 270 ? -30.400 0.532   -46.909 1.00 34.19  ? 270 ASN A HD22   1 
ATOM   4238  N N      . ASP A 1 271 ? -30.855 5.711   -45.497 1.00 27.61  ? 271 ASP A N      1 
ATOM   4239  C CA     . ASP A 1 271 ? -31.638 6.903   -45.829 1.00 32.51  ? 271 ASP A CA     1 
ATOM   4240  C C      . ASP A 1 271 ? -30.961 8.214   -45.411 1.00 33.35  ? 271 ASP A C      1 
ATOM   4241  O O      . ASP A 1 271 ? -30.653 8.414   -44.235 1.00 28.83  ? 271 ASP A O      1 
ATOM   4242  C CB     . ASP A 1 271 ? -33.015 6.818   -45.177 1.00 30.96  ? 271 ASP A CB     1 
ATOM   4243  C CG     . ASP A 1 271 ? -33.929 7.950   -45.610 1.00 33.43  ? 271 ASP A CG     1 
ATOM   4244  O OD1    . ASP A 1 271 ? -34.379 7.930   -46.774 1.00 33.28  ? 271 ASP A OD1    1 
ATOM   4245  O OD2    . ASP A 1 271 ? -34.186 8.858   -44.794 1.00 33.87  ? 271 ASP A OD2    1 
ATOM   4246  H H      . ASP A 1 271 ? -31.149 5.279   -44.814 1.00 33.14  ? 271 ASP A H      1 
ATOM   4247  H HA     . ASP A 1 271 ? -31.768 6.932   -46.790 1.00 39.01  ? 271 ASP A HA     1 
ATOM   4248  H HB2    . ASP A 1 271 ? -33.434 5.980   -45.428 1.00 37.15  ? 271 ASP A HB2    1 
ATOM   4249  H HB3    . ASP A 1 271 ? -32.913 6.864   -44.214 1.00 37.15  ? 271 ASP A HB3    1 
ATOM   4250  N N      . ASP A 1 272 ? -30.761 9.108   -46.381 1.00 32.97  ? 272 ASP A N      1 
ATOM   4251  C CA     . ASP A 1 272 ? -30.095 10.388  -46.142 1.00 32.14  ? 272 ASP A CA     1 
ATOM   4252  C C      . ASP A 1 272 ? -30.814 11.241  -45.100 1.00 34.28  ? 272 ASP A C      1 
ATOM   4253  O O      . ASP A 1 272 ? -30.180 11.802  -44.204 1.00 31.30  ? 272 ASP A O      1 
ATOM   4254  C CB     . ASP A 1 272 ? -29.982 11.187  -47.444 1.00 35.66  ? 272 ASP A CB     1 
ATOM   4255  C CG     . ASP A 1 272 ? -29.038 10.552  -48.450 1.00 38.11  ? 272 ASP A CG     1 
ATOM   4256  O OD1    . ASP A 1 272 ? -28.244 9.667   -48.072 1.00 37.44  ? 272 ASP A OD1    1 
ATOM   4257  O OD2    . ASP A 1 272 ? -29.083 10.951  -49.633 1.00 36.46  ? 272 ASP A OD2    1 
ATOM   4258  H H      . ASP A 1 272 ? -31.006 8.994   -47.197 1.00 39.57  ? 272 ASP A H      1 
ATOM   4259  H HA     . ASP A 1 272 ? -29.198 10.218  -45.814 1.00 38.57  ? 272 ASP A HA     1 
ATOM   4260  H HB2    . ASP A 1 272 ? -30.859 11.248  -47.854 1.00 42.79  ? 272 ASP A HB2    1 
ATOM   4261  H HB3    . ASP A 1 272 ? -29.649 12.075  -47.241 1.00 42.79  ? 272 ASP A HB3    1 
ATOM   4262  N N      . ASP A 1 273 ? -32.133 11.354  -45.222 1.00 32.23  ? 273 ASP A N      1 
ATOM   4263  C CA     . ASP A 1 273 ? -32.892 12.224  -44.331 1.00 35.88  ? 273 ASP A CA     1 
ATOM   4264  C C      . ASP A 1 273 ? -32.864 11.699  -42.898 1.00 34.68  ? 273 ASP A C      1 
ATOM   4265  O O      . ASP A 1 273 ? -32.771 12.479  -41.949 1.00 33.82  ? 273 ASP A O      1 
ATOM   4266  C CB     . ASP A 1 273 ? -34.342 12.369  -44.806 1.00 46.39  ? 273 ASP A CB     1 
ATOM   4267  C CG     . ASP A 1 273 ? -34.477 13.263  -46.033 1.00 48.49  ? 273 ASP A CG     1 
ATOM   4268  O OD1    . ASP A 1 273 ? -33.464 13.840  -46.483 1.00 45.28  ? 273 ASP A OD1    1 
ATOM   4269  O OD2    . ASP A 1 273 ? -35.609 13.395  -46.540 1.00 53.20  ? 273 ASP A OD2    1 
ATOM   4270  H H      . ASP A 1 273 ? -32.609 10.941  -45.808 1.00 38.68  ? 273 ASP A H      1 
ATOM   4271  H HA     . ASP A 1 273 ? -32.485 13.104  -44.328 1.00 43.05  ? 273 ASP A HA     1 
ATOM   4272  H HB2    . ASP A 1 273 ? -34.688 11.492  -45.035 1.00 55.66  ? 273 ASP A HB2    1 
ATOM   4273  H HB3    . ASP A 1 273 ? -34.871 12.758  -44.092 1.00 55.66  ? 273 ASP A HB3    1 
ATOM   4274  N N      . MET A 1 274 ? -32.954 10.383  -42.732 1.00 29.45  ? 274 MET A N      1 
ATOM   4275  C CA     . MET A 1 274 ? -32.849 9.805   -41.396 1.00 29.64  ? 274 MET A CA     1 
ATOM   4276  C C      . MET A 1 274 ? -31.463 10.073  -40.803 1.00 29.89  ? 274 MET A C      1 
ATOM   4277  O O      . MET A 1 274 ? -31.336 10.406  -39.621 1.00 31.36  ? 274 MET A O      1 
ATOM   4278  C CB     . MET A 1 274 ? -33.122 8.305   -41.422 1.00 32.98  ? 274 MET A CB     1 
ATOM   4279  C CG     . MET A 1 274 ? -32.759 7.607   -40.117 1.00 39.92  ? 274 MET A CG     1 
ATOM   4280  S SD     . MET A 1 274 ? -33.310 5.896   -40.061 1.00 45.59  ? 274 MET A SD     1 
ATOM   4281  C CE     . MET A 1 274 ? -35.063 6.156   -39.785 1.00 45.10  ? 274 MET A CE     1 
ATOM   4282  H H      . MET A 1 274 ? -33.074 9.812   -43.364 1.00 35.34  ? 274 MET A H      1 
ATOM   4283  H HA     . MET A 1 274 ? -33.517 10.216  -40.825 1.00 35.57  ? 274 MET A HA     1 
ATOM   4284  H HB2    . MET A 1 274 ? -34.067 8.160   -41.586 1.00 39.57  ? 274 MET A HB2    1 
ATOM   4285  H HB3    . MET A 1 274 ? -32.598 7.902   -42.132 1.00 39.57  ? 274 MET A HB3    1 
ATOM   4286  H HG2    . MET A 1 274 ? -31.795 7.604   -40.012 1.00 47.90  ? 274 MET A HG2    1 
ATOM   4287  H HG3    . MET A 1 274 ? -33.173 8.081   -39.379 1.00 47.90  ? 274 MET A HG3    1 
ATOM   4288  H HE1    . MET A 1 274 ? -35.498 5.294   -39.690 1.00 54.12  ? 274 MET A HE1    1 
ATOM   4289  H HE2    . MET A 1 274 ? -35.181 6.678   -38.976 1.00 54.12  ? 274 MET A HE2    1 
ATOM   4290  H HE3    . MET A 1 274 ? -35.435 6.633   -40.543 1.00 54.12  ? 274 MET A HE3    1 
ATOM   4291  N N      . PHE A 1 275 ? -30.433 9.925   -41.630 1.00 27.77  ? 275 PHE A N      1 
ATOM   4292  C CA     . PHE A 1 275 ? -29.056 10.181  -41.213 1.00 31.77  ? 275 PHE A CA     1 
ATOM   4293  C C      . PHE A 1 275 ? -28.890 11.618  -40.727 1.00 31.02  ? 275 PHE A C      1 
ATOM   4294  O O      . PHE A 1 275 ? -28.333 11.854  -39.657 1.00 26.66  ? 275 PHE A O      1 
ATOM   4295  C CB     . PHE A 1 275 ? -28.093 9.895   -42.368 1.00 28.95  ? 275 PHE A CB     1 
ATOM   4296  C CG     . PHE A 1 275 ? -26.647 10.186  -42.055 1.00 29.41  ? 275 PHE A CG     1 
ATOM   4297  C CD1    . PHE A 1 275 ? -26.037 9.640   -40.939 1.00 29.31  ? 275 PHE A CD1    1 
ATOM   4298  C CD2    . PHE A 1 275 ? -25.890 10.987  -42.901 1.00 31.17  ? 275 PHE A CD2    1 
ATOM   4299  C CE1    . PHE A 1 275 ? -24.702 9.888   -40.666 1.00 27.25  ? 275 PHE A CE1    1 
ATOM   4300  C CE2    . PHE A 1 275 ? -24.551 11.242  -42.630 1.00 34.67  ? 275 PHE A CE2    1 
ATOM   4301  C CZ     . PHE A 1 275 ? -23.958 10.686  -41.509 1.00 31.99  ? 275 PHE A CZ     1 
ATOM   4302  H H      . PHE A 1 275 ? -30.506 9.674   -42.449 1.00 33.33  ? 275 PHE A H      1 
ATOM   4303  H HA     . PHE A 1 275 ? -28.831 9.590   -40.478 1.00 38.13  ? 275 PHE A HA     1 
ATOM   4304  H HB2    . PHE A 1 275 ? -28.161 8.957   -42.604 1.00 34.74  ? 275 PHE A HB2    1 
ATOM   4305  H HB3    . PHE A 1 275 ? -28.345 10.442  -43.128 1.00 34.74  ? 275 PHE A HB3    1 
ATOM   4306  H HD1    . PHE A 1 275 ? -26.529 9.095   -40.368 1.00 35.18  ? 275 PHE A HD1    1 
ATOM   4307  H HD2    . PHE A 1 275 ? -26.284 11.357  -43.658 1.00 37.41  ? 275 PHE A HD2    1 
ATOM   4308  H HE1    . PHE A 1 275 ? -24.307 9.518   -39.910 1.00 32.71  ? 275 PHE A HE1    1 
ATOM   4309  H HE2    . PHE A 1 275 ? -24.054 11.783  -43.201 1.00 41.60  ? 275 PHE A HE2    1 
ATOM   4310  H HZ     . PHE A 1 275 ? -23.064 10.859  -41.320 1.00 38.39  ? 275 PHE A HZ     1 
ATOM   4311  N N      . SER A 1 276 ? -29.390 12.575  -41.503 1.00 29.09  ? 276 SER A N      1 
ATOM   4312  C CA     . SER A 1 276 ? -29.307 13.976  -41.109 1.00 30.81  ? 276 SER A CA     1 
ATOM   4313  C C      . SER A 1 276 ? -30.025 14.210  -39.782 1.00 29.23  ? 276 SER A C      1 
ATOM   4314  O O      . SER A 1 276 ? -29.542 14.950  -38.925 1.00 32.03  ? 276 SER A O      1 
ATOM   4315  C CB     . SER A 1 276 ? -29.889 14.875  -42.199 1.00 33.33  ? 276 SER A CB     1 
ATOM   4316  O OG     . SER A 1 276 ? -29.098 14.802  -43.371 1.00 40.83  ? 276 SER A OG     1 
ATOM   4317  H H      . SER A 1 276 ? -29.780 12.440  -42.258 1.00 34.90  ? 276 SER A H      1 
ATOM   4318  H HA     . SER A 1 276 ? -28.374 14.215  -40.991 1.00 36.97  ? 276 SER A HA     1 
ATOM   4319  H HB2    . SER A 1 276 ? -30.794 14.590  -42.403 1.00 39.99  ? 276 SER A HB2    1 
ATOM   4320  H HB3    . SER A 1 276 ? -29.886 15.791  -41.887 1.00 39.99  ? 276 SER A HB3    1 
ATOM   4321  H HG     . SER A 1 276 ? -29.421 15.297  -43.967 1.00 49.00  ? 276 SER A HG     1 
ATOM   4322  N N      . ALA A 1 277 ? -31.174 13.569  -39.603 1.00 30.96  ? 277 ALA A N      1 
ATOM   4323  C CA     . ALA A 1 277 ? -31.918 13.709  -38.360 1.00 31.30  ? 277 ALA A CA     1 
ATOM   4324  C C      . ALA A 1 277 ? -31.165 13.043  -37.214 1.00 30.58  ? 277 ALA A C      1 
ATOM   4325  O O      . ALA A 1 277 ? -31.170 13.540  -36.084 1.00 29.50  ? 277 ALA A O      1 
ATOM   4326  C CB     . ALA A 1 277 ? -33.310 13.115  -38.497 1.00 31.62  ? 277 ALA A CB     1 
ATOM   4327  H H      . ALA A 1 277 ? -31.542 13.050  -40.182 1.00 37.16  ? 277 ALA A H      1 
ATOM   4328  H HA     . ALA A 1 277 ? -32.013 14.651  -38.151 1.00 37.56  ? 277 ALA A HA     1 
ATOM   4329  H HB1    . ALA A 1 277 ? -33.782 13.222  -37.657 1.00 37.94  ? 277 ALA A HB1    1 
ATOM   4330  H HB2    . ALA A 1 277 ? -33.783 13.580  -39.204 1.00 37.94  ? 277 ALA A HB2    1 
ATOM   4331  H HB3    . ALA A 1 277 ? -33.231 12.173  -38.715 1.00 37.94  ? 277 ALA A HB3    1 
ATOM   4332  N N      . ALA A 1 278 ? -30.525 11.914  -37.504 1.00 28.04  ? 278 ALA A N      1 
ATOM   4333  C CA     . ALA A 1 278 ? -29.762 11.192  -36.488 1.00 28.86  ? 278 ALA A CA     1 
ATOM   4334  C C      . ALA A 1 278 ? -28.565 12.017  -36.031 1.00 26.83  ? 278 ALA A C      1 
ATOM   4335  O O      . ALA A 1 278 ? -28.232 12.045  -34.843 1.00 27.21  ? 278 ALA A O      1 
ATOM   4336  C CB     . ALA A 1 278 ? -29.303 9.844   -37.025 1.00 30.11  ? 278 ALA A CB     1 
ATOM   4337  H H      . ALA A 1 278 ? -30.516 11.544  -38.280 1.00 33.65  ? 278 ALA A H      1 
ATOM   4338  H HA     . ALA A 1 278 ? -30.329 11.034  -35.717 1.00 34.63  ? 278 ALA A HA     1 
ATOM   4339  H HB1    . ALA A 1 278 ? -28.802 9.384   -36.334 1.00 36.13  ? 278 ALA A HB1    1 
ATOM   4340  H HB2    . ALA A 1 278 ? -30.082 9.322   -37.273 1.00 36.13  ? 278 ALA A HB2    1 
ATOM   4341  H HB3    . ALA A 1 278 ? -28.740 9.989   -37.802 1.00 36.13  ? 278 ALA A HB3    1 
ATOM   4342  N N      . ARG A 1 279 ? -27.928 12.701  -36.978 1.00 26.95  ? 279 ARG A N      1 
ATOM   4343  C CA     . ARG A 1 279 ? -26.740 13.486  -36.667 1.00 29.15  ? 279 ARG A CA     1 
ATOM   4344  C C      . ARG A 1 279 ? -27.095 14.622  -35.720 1.00 30.34  ? 279 ARG A C      1 
ATOM   4345  O O      . ARG A 1 279 ? -26.307 14.982  -34.847 1.00 30.35  ? 279 ARG A O      1 
ATOM   4346  C CB     . ARG A 1 279 ? -26.089 14.030  -37.942 1.00 29.01  ? 279 ARG A CB     1 
ATOM   4347  C CG     . ARG A 1 279 ? -25.231 12.993  -38.646 1.00 31.40  ? 279 ARG A CG     1 
ATOM   4348  C CD     . ARG A 1 279 ? -24.074 13.601  -39.419 1.00 34.43  ? 279 ARG A CD     1 
ATOM   4349  N NE     . ARG A 1 279 ? -24.515 14.347  -40.588 1.00 38.73  ? 279 ARG A NE     1 
ATOM   4350  C CZ     . ARG A 1 279 ? -23.776 14.550  -41.677 1.00 44.37  ? 279 ARG A CZ     1 
ATOM   4351  N NH1    . ARG A 1 279 ? -22.540 14.061  -41.765 1.00 39.85  ? 279 ARG A NH1    1 
ATOM   4352  N NH2    . ARG A 1 279 ? -24.278 15.245  -42.688 1.00 42.63  ? 279 ARG A NH2    1 
ATOM   4353  H H      . ARG A 1 279 ? -28.163 12.726  -37.805 1.00 32.34  ? 279 ARG A H      1 
ATOM   4354  H HA     . ARG A 1 279 ? -26.096 12.917  -36.218 1.00 34.98  ? 279 ARG A HA     1 
ATOM   4355  H HB2    . ARG A 1 279 ? -26.784 14.312  -38.557 1.00 34.81  ? 279 ARG A HB2    1 
ATOM   4356  H HB3    . ARG A 1 279 ? -25.523 14.783  -37.712 1.00 34.81  ? 279 ARG A HB3    1 
ATOM   4357  H HG2    . ARG A 1 279 ? -24.861 12.386  -37.987 1.00 37.68  ? 279 ARG A HG2    1 
ATOM   4358  H HG3    . ARG A 1 279 ? -25.784 12.502  -39.274 1.00 37.68  ? 279 ARG A HG3    1 
ATOM   4359  H HD2    . ARG A 1 279 ? -23.588 14.208  -38.839 1.00 41.32  ? 279 ARG A HD2    1 
ATOM   4360  H HD3    . ARG A 1 279 ? -23.491 12.885  -39.715 1.00 41.32  ? 279 ARG A HD3    1 
ATOM   4361  H HE     . ARG A 1 279 ? -25.308 14.680  -40.575 1.00 46.48  ? 279 ARG A HE     1 
ATOM   4362  H HH11   . ARG A 1 279 ? -22.204 13.609  -41.116 1.00 47.82  ? 279 ARG A HH11   1 
ATOM   4363  H HH12   . ARG A 1 279 ? -22.075 14.200  -42.475 1.00 47.82  ? 279 ARG A HH12   1 
ATOM   4364  H HH21   . ARG A 1 279 ? -25.076 15.563  -42.637 1.00 51.15  ? 279 ARG A HH21   1 
ATOM   4365  H HH22   . ARG A 1 279 ? -23.806 15.379  -43.394 1.00 51.15  ? 279 ARG A HH22   1 
ATOM   4366  N N      . GLU A 1 280 ? -28.294 15.166  -35.880 1.00 30.26  ? 280 GLU A N      1 
ATOM   4367  C CA     . GLU A 1 280 ? -28.759 16.232  -35.007 1.00 35.86  ? 280 GLU A CA     1 
ATOM   4368  C C      . GLU A 1 280 ? -29.057 15.687  -33.618 1.00 30.86  ? 280 GLU A C      1 
ATOM   4369  O O      . GLU A 1 280 ? -28.688 16.284  -32.602 1.00 30.42  ? 280 GLU A O      1 
ATOM   4370  C CB     . GLU A 1 280 ? -30.005 16.896  -35.591 1.00 41.81  ? 280 GLU A CB     1 
ATOM   4371  C CG     . GLU A 1 280 ? -30.479 18.109  -34.814 1.00 49.91  ? 280 GLU A CG     1 
ATOM   4372  C CD     . GLU A 1 280 ? -31.657 18.795  -35.483 1.00 71.15  ? 280 GLU A CD     1 
ATOM   4373  O OE1    . GLU A 1 280 ? -32.359 18.132  -36.279 1.00 69.06  ? 280 GLU A OE1    1 
ATOM   4374  O OE2    . GLU A 1 280 ? -31.875 19.997  -35.221 1.00 70.99  ? 280 GLU A OE2    1 
ATOM   4375  H H      . GLU A 1 280 ? -28.858 14.936  -36.487 1.00 36.31  ? 280 GLU A H      1 
ATOM   4376  H HA     . GLU A 1 280 ? -28.066 16.906  -34.927 1.00 43.03  ? 280 GLU A HA     1 
ATOM   4377  H HB2    . GLU A 1 280 ? -29.811 17.182  -36.497 1.00 50.17  ? 280 GLU A HB2    1 
ATOM   4378  H HB3    . GLU A 1 280 ? -30.727 16.248  -35.599 1.00 50.17  ? 280 GLU A HB3    1 
ATOM   4379  H HG2    . GLU A 1 280 ? -30.757 17.831  -33.927 1.00 59.90  ? 280 GLU A HG2    1 
ATOM   4380  H HG3    . GLU A 1 280 ? -29.753 18.749  -34.751 1.00 59.90  ? 280 GLU A HG3    1 
ATOM   4381  N N      . LEU A 1 281 ? -29.712 14.536  -33.579 1.00 24.93  ? 281 LEU A N      1 
ATOM   4382  C CA     . LEU A 1 281 ? -30.173 13.966  -32.326 1.00 27.85  ? 281 LEU A CA     1 
ATOM   4383  C C      . LEU A 1 281 ? -29.045 13.362  -31.477 1.00 26.31  ? 281 LEU A C      1 
ATOM   4384  O O      . LEU A 1 281 ? -29.095 13.410  -30.240 1.00 26.33  ? 281 LEU A O      1 
ATOM   4385  C CB     . LEU A 1 281 ? -31.230 12.899  -32.618 1.00 29.15  ? 281 LEU A CB     1 
ATOM   4386  C CG     . LEU A 1 281 ? -31.983 12.347  -31.408 1.00 30.39  ? 281 LEU A CG     1 
ATOM   4387  C CD1    . LEU A 1 281 ? -32.859 13.419  -30.763 1.00 32.60  ? 281 LEU A CD1    1 
ATOM   4388  C CD2    . LEU A 1 281 ? -32.829 11.149  -31.823 1.00 32.15  ? 281 LEU A CD2    1 
ATOM   4389  H H      . LEU A 1 281 ? -29.903 14.062  -34.271 1.00 29.91  ? 281 LEU A H      1 
ATOM   4390  H HA     . LEU A 1 281 ? -30.593 14.666  -31.803 1.00 33.42  ? 281 LEU A HA     1 
ATOM   4391  H HB2    . LEU A 1 281 ? -31.889 13.280  -33.219 1.00 34.98  ? 281 LEU A HB2    1 
ATOM   4392  H HB3    . LEU A 1 281 ? -30.794 12.150  -33.053 1.00 34.98  ? 281 LEU A HB3    1 
ATOM   4393  H HG     . LEU A 1 281 ? -31.342 12.045  -30.746 1.00 36.47  ? 281 LEU A HG     1 
ATOM   4394  H HD11   . LEU A 1 281 ? -33.388 13.012  -30.059 1.00 39.13  ? 281 LEU A HD11   1 
ATOM   4395  H HD12   . LEU A 1 281 ? -32.290 14.111  -30.391 1.00 39.13  ? 281 LEU A HD12   1 
ATOM   4396  H HD13   . LEU A 1 281 ? -33.443 13.797  -31.439 1.00 39.13  ? 281 LEU A HD13   1 
ATOM   4397  H HD21   . LEU A 1 281 ? -33.301 10.812  -31.045 1.00 38.58  ? 281 LEU A HD21   1 
ATOM   4398  H HD22   . LEU A 1 281 ? -33.464 11.431  -32.500 1.00 38.58  ? 281 LEU A HD22   1 
ATOM   4399  H HD23   . LEU A 1 281 ? -32.247 10.461  -32.182 1.00 38.58  ? 281 LEU A HD23   1 
ATOM   4400  N N      . VAL A 1 282 ? -28.038 12.780  -32.121 1.00 21.35  ? 282 VAL A N      1 
ATOM   4401  C CA     . VAL A 1 282 ? -26.989 12.086  -31.369 1.00 26.45  ? 282 VAL A CA     1 
ATOM   4402  C C      . VAL A 1 282 ? -26.207 13.074  -30.485 1.00 22.06  ? 282 VAL A C      1 
ATOM   4403  O O      . VAL A 1 282 ? -25.679 12.698  -29.438 1.00 22.54  ? 282 VAL A O      1 
ATOM   4404  C CB     . VAL A 1 282 ? -26.022 11.315  -32.314 1.00 23.57  ? 282 VAL A CB     1 
ATOM   4405  C CG1    . VAL A 1 282 ? -25.267 12.261  -33.225 1.00 22.99  ? 282 VAL A CG1    1 
ATOM   4406  C CG2    . VAL A 1 282 ? -25.056 10.465  -31.512 1.00 26.17  ? 282 VAL A CG2    1 
ATOM   4407  H H      . VAL A 1 282 ? -27.937 12.770  -32.975 1.00 25.63  ? 282 VAL A H      1 
ATOM   4408  H HA     . VAL A 1 282 ? -27.407 11.436  -30.783 1.00 31.74  ? 282 VAL A HA     1 
ATOM   4409  H HB     . VAL A 1 282 ? -26.544 10.719  -32.874 1.00 28.29  ? 282 VAL A HB     1 
ATOM   4410  H HG11   . VAL A 1 282 ? -24.730 11.740  -33.842 1.00 27.58  ? 282 VAL A HG11   1 
ATOM   4411  H HG12   . VAL A 1 282 ? -25.906 12.798  -33.717 1.00 27.58  ? 282 VAL A HG12   1 
ATOM   4412  H HG13   . VAL A 1 282 ? -24.694 12.832  -32.690 1.00 27.58  ? 282 VAL A HG13   1 
ATOM   4413  H HG21   . VAL A 1 282 ? -24.569 9.885   -32.119 1.00 31.40  ? 282 VAL A HG21   1 
ATOM   4414  H HG22   . VAL A 1 282 ? -24.437 11.046  -31.043 1.00 31.40  ? 282 VAL A HG22   1 
ATOM   4415  H HG23   . VAL A 1 282 ? -25.559 9.931   -30.878 1.00 31.40  ? 282 VAL A HG23   1 
ATOM   4416  N N      . VAL A 1 283 ? -26.173 14.343  -30.886 1.00 23.50  ? 283 VAL A N      1 
ATOM   4417  C CA     . VAL A 1 283 ? -25.394 15.354  -30.171 1.00 22.31  ? 283 VAL A CA     1 
ATOM   4418  C C      . VAL A 1 283 ? -25.805 15.441  -28.709 1.00 26.37  ? 283 VAL A C      1 
ATOM   4419  O O      . VAL A 1 283 ? -24.974 15.536  -27.810 1.00 23.67  ? 283 VAL A O      1 
ATOM   4420  C CB     . VAL A 1 283 ? -25.554 16.740  -30.822 1.00 26.19  ? 283 VAL A CB     1 
ATOM   4421  C CG1    . VAL A 1 283 ? -24.871 17.814  -30.001 1.00 26.69  ? 283 VAL A CG1    1 
ATOM   4422  C CG2    . VAL A 1 283 ? -24.982 16.720  -32.217 1.00 26.25  ? 283 VAL A CG2    1 
ATOM   4423  H H      . VAL A 1 283 ? -26.594 14.647  -31.572 1.00 28.21  ? 283 VAL A H      1 
ATOM   4424  H HA     . VAL A 1 283 ? -24.455 15.115  -30.205 1.00 26.78  ? 283 VAL A HA     1 
ATOM   4425  H HB     . VAL A 1 283 ? -26.497 16.958  -30.883 1.00 31.43  ? 283 VAL A HB     1 
ATOM   4426  H HG11   . VAL A 1 283 ? -24.724 18.591  -30.562 1.00 32.02  ? 283 VAL A HG11   1 
ATOM   4427  H HG12   . VAL A 1 283 ? -25.439 18.052  -29.251 1.00 32.02  ? 283 VAL A HG12   1 
ATOM   4428  H HG13   . VAL A 1 283 ? -24.021 17.474  -29.681 1.00 32.02  ? 283 VAL A HG13   1 
ATOM   4429  H HG21   . VAL A 1 283 ? -25.111 17.591  -32.623 1.00 31.50  ? 283 VAL A HG21   1 
ATOM   4430  H HG22   . VAL A 1 283 ? -24.035 16.514  -32.167 1.00 31.50  ? 283 VAL A HG22   1 
ATOM   4431  H HG23   . VAL A 1 283 ? -25.441 16.042  -32.736 1.00 31.50  ? 283 VAL A HG23   1 
ATOM   4432  N N      . VAL A 1 284 ? -27.054 15.344  -28.299 1.00 24.70  ? 284 VAL A N      1 
ATOM   4433  C CA     . VAL A 1 284 ? -27.540 15.607  -26.961 1.00 25.96  ? 284 VAL A CA     1 
ATOM   4434  C C      . VAL A 1 284 ? -27.648 14.345  -26.095 1.00 26.50  ? 284 VAL A C      1 
ATOM   4435  O O      . VAL A 1 284 ? -27.483 14.406  -24.870 1.00 27.30  ? 284 VAL A O      1 
ATOM   4436  C CB     . VAL A 1 284 ? -28.912 16.310  -27.081 1.00 32.49  ? 284 VAL A CB     1 
ATOM   4437  C CG1    . VAL A 1 284 ? -28.802 17.649  -27.743 1.00 40.85  ? 284 VAL A CG1    1 
ATOM   4438  C CG2    . VAL A 1 284 ? -29.908 15.391  -27.794 1.00 34.75  ? 284 VAL A CG2    1 
ATOM   4439  H H      . VAL A 1 284 ? -27.684 15.102  -28.830 1.00 29.64  ? 284 VAL A H      1 
ATOM   4440  H HA     . VAL A 1 284 ? -26.936 16.221  -26.515 1.00 31.15  ? 284 VAL A HA     1 
ATOM   4441  H HB     . VAL A 1 284 ? -29.253 16.461  -26.186 1.00 38.98  ? 284 VAL A HB     1 
ATOM   4442  H HG11   . VAL A 1 284 ? -29.678 18.066  -27.758 1.00 49.02  ? 284 VAL A HG11   1 
ATOM   4443  H HG12   . VAL A 1 284 ? -28.182 18.199  -27.240 1.00 49.02  ? 284 VAL A HG12   1 
ATOM   4444  H HG13   . VAL A 1 284 ? -28.478 17.528  -28.649 1.00 49.02  ? 284 VAL A HG13   1 
ATOM   4445  H HG21   . VAL A 1 284 ? -30.800 15.754  -27.679 1.00 41.70  ? 284 VAL A HG21   1 
ATOM   4446  H HG22   . VAL A 1 284 ? -29.690 15.358  -28.738 1.00 41.70  ? 284 VAL A HG22   1 
ATOM   4447  H HG23   . VAL A 1 284 ? -29.868 14.502  -27.411 1.00 41.70  ? 284 VAL A HG23   1 
ATOM   4448  N N      . TYR A 1 285 ? -27.537 13.185  -26.794 1.00 27.98  ? 285 TYR A N      1 
ATOM   4449  C CA     . TYR A 1 285 ? -27.512 11.969  -25.974 1.00 29.08  ? 285 TYR A CA     1 
ATOM   4450  C C      . TYR A 1 285 ? -26.128 11.323  -25.863 1.00 29.29  ? 285 TYR A C      1 
ATOM   4451  O O      . TYR A 1 285 ? -25.745 10.849  -24.794 1.00 24.37  ? 285 TYR A O      1 
ATOM   4452  C CB     . TYR A 1 285 ? -28.508 10.947  -26.530 1.00 29.30  ? 285 TYR A CB     1 
ATOM   4453  C CG     . TYR A 1 285 ? -29.944 11.294  -26.214 1.00 33.46  ? 285 TYR A CG     1 
ATOM   4454  C CD1    . TYR A 1 285 ? -30.471 11.059  -24.948 1.00 32.34  ? 285 TYR A CD1    1 
ATOM   4455  C CD2    . TYR A 1 285 ? -30.770 11.862  -27.176 1.00 33.03  ? 285 TYR A CD2    1 
ATOM   4456  C CE1    . TYR A 1 285 ? -31.783 11.373  -24.645 1.00 32.47  ? 285 TYR A CE1    1 
ATOM   4457  C CE2    . TYR A 1 285 ? -32.091 12.184  -26.882 1.00 39.71  ? 285 TYR A CE2    1 
ATOM   4458  C CZ     . TYR A 1 285 ? -32.590 11.934  -25.614 1.00 40.95  ? 285 TYR A CZ     1 
ATOM   4459  O OH     . TYR A 1 285 ? -33.895 12.247  -25.304 1.00 58.45  ? 285 TYR A OH     1 
ATOM   4460  H H      . TYR A 1 285 ? -27.482 13.086  -27.646 1.00 33.58  ? 285 TYR A H      1 
ATOM   4461  H HA     . TYR A 1 285 ? -27.807 12.166  -25.073 1.00 34.90  ? 285 TYR A HA     1 
ATOM   4462  H HB2    . TYR A 1 285 ? -28.415 10.908  -27.495 1.00 35.16  ? 285 TYR A HB2    1 
ATOM   4463  H HB3    . TYR A 1 285 ? -28.318 10.078  -26.143 1.00 35.16  ? 285 TYR A HB3    1 
ATOM   4464  H HD1    . TYR A 1 285 ? -29.931 10.680  -24.293 1.00 38.81  ? 285 TYR A HD1    1 
ATOM   4465  H HD2    . TYR A 1 285 ? -30.436 12.028  -28.028 1.00 39.64  ? 285 TYR A HD2    1 
ATOM   4466  H HE1    . TYR A 1 285 ? -32.119 11.208  -23.794 1.00 38.96  ? 285 TYR A HE1    1 
ATOM   4467  H HE2    . TYR A 1 285 ? -32.637 12.562  -27.533 1.00 47.65  ? 285 TYR A HE2    1 
ATOM   4468  H HH     . TYR A 1 285 ? -34.278 12.580  -25.974 1.00 70.15  ? 285 TYR A HH     1 
ATOM   4469  N N      . GLU A 1 286 ? -25.384 11.305  -26.963 1.00 22.70  ? 286 GLU A N      1 
ATOM   4470  C CA     . GLU A 1 286 ? -24.123 10.564  -27.026 1.00 25.07  ? 286 GLU A CA     1 
ATOM   4471  C C      . GLU A 1 286 ? -22.918 11.480  -27.182 1.00 24.48  ? 286 GLU A C      1 
ATOM   4472  O O      . GLU A 1 286 ? -21.935 11.343  -26.456 1.00 22.67  ? 286 GLU A O      1 
ATOM   4473  C CB     . GLU A 1 286 ? -24.154 9.572   -28.184 1.00 24.79  ? 286 GLU A CB     1 
ATOM   4474  C CG     . GLU A 1 286 ? -25.265 8.545   -28.090 1.00 27.72  ? 286 GLU A CG     1 
ATOM   4475  C CD     . GLU A 1 286 ? -25.010 7.505   -27.022 1.00 31.92  ? 286 GLU A CD     1 
ATOM   4476  O OE1    . GLU A 1 286 ? -25.991 7.056   -26.398 1.00 36.45  ? 286 GLU A OE1    1 
ATOM   4477  O OE2    . GLU A 1 286 ? -23.833 7.138   -26.803 1.00 29.53  ? 286 GLU A OE2    1 
ATOM   4478  H H      . GLU A 1 286 ? -25.586 11.715  -27.692 1.00 27.24  ? 286 GLU A H      1 
ATOM   4479  H HA     . GLU A 1 286 ? -24.004 10.053  -26.212 1.00 30.09  ? 286 GLU A HA     1 
ATOM   4480  H HB2    . GLU A 1 286 ? -24.280 10.067  -29.006 1.00 29.74  ? 286 GLU A HB2    1 
ATOM   4481  H HB3    . GLU A 1 286 ? -23.307 9.100   -28.216 1.00 29.74  ? 286 GLU A HB3    1 
ATOM   4482  H HG2    . GLU A 1 286 ? -26.098 8.995   -27.878 1.00 33.26  ? 286 GLU A HG2    1 
ATOM   4483  H HG3    . GLU A 1 286 ? -25.343 8.087   -28.941 1.00 33.26  ? 286 GLU A HG3    1 
ATOM   4484  N N      . GLY A 1 287 ? -23.002 12.397  -28.144 1.00 19.14  ? 287 GLY A N      1 
ATOM   4485  C CA     . GLY A 1 287 ? -21.907 13.293  -28.473 1.00 22.12  ? 287 GLY A CA     1 
ATOM   4486  C C      . GLY A 1 287 ? -21.986 13.671  -29.945 1.00 24.34  ? 287 GLY A C      1 
ATOM   4487  O O      . GLY A 1 287 ? -22.880 13.213  -30.648 1.00 21.18  ? 287 GLY A O      1 
ATOM   4488  H H      . GLY A 1 287 ? -23.702 12.519  -28.629 1.00 22.97  ? 287 GLY A H      1 
ATOM   4489  H HA2    . GLY A 1 287 ? -21.963 14.099  -27.936 1.00 26.54  ? 287 GLY A HA2    1 
ATOM   4490  H HA3    . GLY A 1 287 ? -21.056 12.858  -28.305 1.00 26.54  ? 287 GLY A HA3    1 
ATOM   4491  N N      . MET A 1 288 ? -21.068 14.521  -30.401 1.00 22.38  ? 288 MET A N      1 
ATOM   4492  C CA     . MET A 1 288 ? -20.987 14.905  -31.811 1.00 21.31  ? 288 MET A CA     1 
ATOM   4493  C C      . MET A 1 288 ? -20.939 13.654  -32.708 1.00 23.43  ? 288 MET A C      1 
ATOM   4494  O O      . MET A 1 288 ? -20.389 12.628  -32.314 1.00 21.68  ? 288 MET A O      1 
ATOM   4495  C CB     . MET A 1 288 ? -19.751 15.780  -32.028 1.00 26.94  ? 288 MET A CB     1 
ATOM   4496  C CG     . MET A 1 288 ? -19.820 16.782  -33.182 1.00 39.68  ? 288 MET A CG     1 
ATOM   4497  S SD     . MET A 1 288 ? -21.150 18.017  -33.071 1.00 34.87  ? 288 MET A SD     1 
ATOM   4498  C CE     . MET A 1 288 ? -21.120 18.446  -31.341 1.00 31.75  ? 288 MET A CE     1 
ATOM   4499  H H      . MET A 1 288 ? -20.472 14.894  -29.906 1.00 26.86  ? 288 MET A H      1 
ATOM   4500  H HA     . MET A 1 288 ? -21.769 15.434  -32.024 1.00 25.57  ? 288 MET A HA     1 
ATOM   4501  H HB2    . MET A 1 288 ? -19.581 16.280  -31.215 1.00 32.33  ? 288 MET A HB2    1 
ATOM   4502  H HB3    . MET A 1 288 ? -18.997 15.195  -32.204 1.00 32.33  ? 288 MET A HB3    1 
ATOM   4503  H HG2    . MET A 1 288 ? -18.981 17.269  -33.207 1.00 47.62  ? 288 MET A HG2    1 
ATOM   4504  H HG3    . MET A 1 288 ? -19.929 16.295  -34.012 1.00 47.62  ? 288 MET A HG3    1 
ATOM   4505  H HE1    . MET A 1 288 ? -21.725 19.189  -31.190 1.00 38.10  ? 288 MET A HE1    1 
ATOM   4506  H HE2    . MET A 1 288 ? -21.404 17.678  -30.821 1.00 38.10  ? 288 MET A HE2    1 
ATOM   4507  H HE3    . MET A 1 288 ? -20.217 18.699  -31.094 1.00 38.10  ? 288 MET A HE3    1 
ATOM   4508  N N      . PRO A 1 289 ? -21.517 13.728  -33.921 1.00 20.72  ? 289 PRO A N      1 
ATOM   4509  C CA     . PRO A 1 289 ? -21.549 12.528  -34.778 1.00 22.33  ? 289 PRO A CA     1 
ATOM   4510  C C      . PRO A 1 289 ? -20.172 11.987  -35.178 1.00 24.81  ? 289 PRO A C      1 
ATOM   4511  O O      . PRO A 1 289 ? -20.087 10.884  -35.739 1.00 21.96  ? 289 PRO A O      1 
ATOM   4512  C CB     . PRO A 1 289 ? -22.300 13.005  -36.025 1.00 25.89  ? 289 PRO A CB     1 
ATOM   4513  C CG     . PRO A 1 289 ? -23.075 14.205  -35.586 1.00 24.16  ? 289 PRO A CG     1 
ATOM   4514  C CD     . PRO A 1 289 ? -22.260 14.854  -34.519 1.00 26.48  ? 289 PRO A CD     1 
ATOM   4515  H HA     . PRO A 1 289 ? -22.058 11.822  -34.349 1.00 26.79  ? 289 PRO A HA     1 
ATOM   4516  H HB2    . PRO A 1 289 ? -21.664 13.243  -36.718 1.00 31.07  ? 289 PRO A HB2    1 
ATOM   4517  H HB3    . PRO A 1 289 ? -22.897 12.306  -36.333 1.00 31.07  ? 289 PRO A HB3    1 
ATOM   4518  H HG2    . PRO A 1 289 ? -23.194 14.807  -36.337 1.00 29.00  ? 289 PRO A HG2    1 
ATOM   4519  H HG3    . PRO A 1 289 ? -23.934 13.925  -35.235 1.00 29.00  ? 289 PRO A HG3    1 
ATOM   4520  H HD2    . PRO A 1 289 ? -21.653 15.496  -34.916 1.00 31.77  ? 289 PRO A HD2    1 
ATOM   4521  H HD3    . PRO A 1 289 ? -22.843 15.270  -33.866 1.00 31.77  ? 289 PRO A HD3    1 
ATOM   4522  N N      . SER A 1 290 ? -19.126 12.765  -34.907 1.00 24.70  ? 290 SER A N      1 
ATOM   4523  C CA     . SER A 1 290 ? -17.756 12.388  -35.222 1.00 22.96  ? 290 SER A CA     1 
ATOM   4524  C C      . SER A 1 290 ? -17.076 11.534  -34.144 1.00 21.00  ? 290 SER A C      1 
ATOM   4525  O O      . SER A 1 290 ? -15.923 11.165  -34.306 1.00 20.55  ? 290 SER A O      1 
ATOM   4526  C CB     . SER A 1 290 ? -16.927 13.654  -35.467 1.00 22.03  ? 290 SER A CB     1 
ATOM   4527  O OG     . SER A 1 290 ? -17.293 14.674  -34.547 1.00 25.56  ? 290 SER A OG     1 
ATOM   4528  H H      . SER A 1 290 ? -19.187 13.537  -34.534 1.00 29.65  ? 290 SER A H      1 
ATOM   4529  H HA     . SER A 1 290 ? -17.756 11.875  -36.045 1.00 27.55  ? 290 SER A HA     1 
ATOM   4530  H HB2    . SER A 1 290 ? -15.986 13.449  -35.356 1.00 26.44  ? 290 SER A HB2    1 
ATOM   4531  H HB3    . SER A 1 290 ? -17.093 13.969  -36.369 1.00 26.44  ? 290 SER A HB3    1 
ATOM   4532  H HG     . SER A 1 290 ? -16.836 15.365  -34.687 1.00 30.67  ? 290 SER A HG     1 
ATOM   4533  N N      . TYR A 1 291 ? -17.764 11.236  -33.039 1.00 20.94  ? 291 TYR A N      1 
ATOM   4534  C CA     . TYR A 1 291 ? -17.206 10.309  -32.045 1.00 20.17  ? 291 TYR A CA     1 
ATOM   4535  C C      . TYR A 1 291 ? -18.305 9.574   -31.267 1.00 22.45  ? 291 TYR A C      1 
ATOM   4536  O O      . TYR A 1 291 ? -18.073 8.475   -30.773 1.00 20.37  ? 291 TYR A O      1 
ATOM   4537  C CB     . TYR A 1 291 ? -16.251 11.035  -31.072 1.00 18.73  ? 291 TYR A CB     1 
ATOM   4538  C CG     . TYR A 1 291 ? -16.932 11.980  -30.103 1.00 19.77  ? 291 TYR A CG     1 
ATOM   4539  C CD1    . TYR A 1 291 ? -17.416 11.529  -28.886 1.00 20.68  ? 291 TYR A CD1    1 
ATOM   4540  C CD2    . TYR A 1 291 ? -17.100 13.321  -30.418 1.00 17.88  ? 291 TYR A CD2    1 
ATOM   4541  C CE1    . TYR A 1 291 ? -18.057 12.384  -28.009 1.00 18.56  ? 291 TYR A CE1    1 
ATOM   4542  C CE2    . TYR A 1 291 ? -17.739 14.194  -29.538 1.00 21.84  ? 291 TYR A CE2    1 
ATOM   4543  C CZ     . TYR A 1 291 ? -18.221 13.713  -28.342 1.00 22.03  ? 291 TYR A CZ     1 
ATOM   4544  O OH     . TYR A 1 291 ? -18.861 14.549  -27.463 1.00 22.00  ? 291 TYR A OH     1 
ATOM   4545  H H      . TYR A 1 291 ? -18.539 11.552  -32.843 1.00 25.13  ? 291 TYR A H      1 
ATOM   4546  H HA     . TYR A 1 291 ? -16.688 9.635   -32.509 1.00 24.20  ? 291 TYR A HA     1 
ATOM   4547  H HB2    . TYR A 1 291 ? -15.777 10.370  -30.549 1.00 22.47  ? 291 TYR A HB2    1 
ATOM   4548  H HB3    . TYR A 1 291 ? -15.617 11.554  -31.591 1.00 22.47  ? 291 TYR A HB3    1 
ATOM   4549  H HD1    . TYR A 1 291 ? -17.319 10.632  -28.660 1.00 24.82  ? 291 TYR A HD1    1 
ATOM   4550  H HD2    . TYR A 1 291 ? -16.784 13.642  -31.231 1.00 21.46  ? 291 TYR A HD2    1 
ATOM   4551  H HE1    . TYR A 1 291 ? -18.380 12.063  -27.198 1.00 22.27  ? 291 TYR A HE1    1 
ATOM   4552  H HE2    . TYR A 1 291 ? -17.851 15.089  -29.764 1.00 26.20  ? 291 TYR A HE2    1 
ATOM   4553  H HH     . TYR A 1 291 ? -18.975 15.303  -27.814 1.00 26.40  ? 291 TYR A HH     1 
ATOM   4554  N N      . GLY A 1 292 ? -19.492 10.172  -31.162 1.00 21.18  ? 292 GLY A N      1 
ATOM   4555  C CA     . GLY A 1 292 ? -20.663 9.488   -30.628 1.00 21.57  ? 292 GLY A CA     1 
ATOM   4556  C C      . GLY A 1 292 ? -20.531 8.849   -29.250 1.00 21.34  ? 292 GLY A C      1 
ATOM   4557  O O      . GLY A 1 292 ? -21.044 7.756   -29.007 1.00 24.22  ? 292 GLY A O      1 
ATOM   4558  H H      . GLY A 1 292 ? -19.644 10.985  -31.395 1.00 25.42  ? 292 GLY A H      1 
ATOM   4559  H HA2    . GLY A 1 292 ? -21.398 10.120  -30.589 1.00 25.89  ? 292 GLY A HA2    1 
ATOM   4560  H HA3    . GLY A 1 292 ? -20.909 8.787   -31.249 1.00 25.89  ? 292 GLY A HA3    1 
ATOM   4561  N N      . GLY A 1 293 ? -19.853 9.527   -28.338 1.00 20.60  ? 293 GLY A N      1 
ATOM   4562  C CA     . GLY A 1 293 ? -19.737 9.039   -26.972 1.00 22.80  ? 293 GLY A CA     1 
ATOM   4563  C C      . GLY A 1 293 ? -18.640 8.006   -26.786 1.00 19.33  ? 293 GLY A C      1 
ATOM   4564  O O      . GLY A 1 293 ? -18.632 7.292   -25.775 1.00 20.48  ? 293 GLY A O      1 
ATOM   4565  H H      . GLY A 1 293 ? -19.464 10.276  -28.481 1.00 24.72  ? 293 GLY A H      1 
ATOM   4566  H HA2    . GLY A 1 293 ? -19.550 9.787   -26.383 1.00 27.36  ? 293 GLY A HA2    1 
ATOM   4567  H HA3    . GLY A 1 293 ? -20.579 8.642   -26.698 1.00 27.36  ? 293 GLY A HA3    1 
ATOM   4568  N N      . LEU A 1 294 ? -17.727 7.935   -27.759 1.00 17.70  ? 294 LEU A N      1 
ATOM   4569  C CA     . LEU A 1 294 ? -16.555 7.060   -27.698 1.00 17.46  ? 294 LEU A CA     1 
ATOM   4570  C C      . LEU A 1 294 ? -15.261 7.853   -27.799 1.00 18.54  ? 294 LEU A C      1 
ATOM   4571  O O      . LEU A 1 294 ? -15.164 8.815   -28.560 1.00 19.02  ? 294 LEU A O      1 
ATOM   4572  C CB     . LEU A 1 294 ? -16.577 6.025   -28.833 1.00 18.29  ? 294 LEU A CB     1 
ATOM   4573  C CG     . LEU A 1 294 ? -17.708 4.991   -28.833 1.00 16.43  ? 294 LEU A CG     1 
ATOM   4574  C CD1    . LEU A 1 294 ? -17.694 4.157   -30.119 1.00 19.47  ? 294 LEU A CD1    1 
ATOM   4575  C CD2    . LEU A 1 294 ? -17.592 4.111   -27.613 1.00 22.54  ? 294 LEU A CD2    1 
ATOM   4576  H H      . LEU A 1 294 ? -17.766 8.397   -28.483 1.00 21.24  ? 294 LEU A H      1 
ATOM   4577  H HA     . LEU A 1 294 ? -16.544 6.587   -26.852 1.00 20.96  ? 294 LEU A HA     1 
ATOM   4578  H HB2    . LEU A 1 294 ? -16.632 6.505   -29.674 1.00 21.95  ? 294 LEU A HB2    1 
ATOM   4579  H HB3    . LEU A 1 294 ? -15.742 5.532   -28.804 1.00 21.95  ? 294 LEU A HB3    1 
ATOM   4580  H HG     . LEU A 1 294 ? -18.559 5.455   -28.787 1.00 19.72  ? 294 LEU A HG     1 
ATOM   4581  H HD11   . LEU A 1 294 ? -18.420 3.514   -30.086 1.00 23.37  ? 294 LEU A HD11   1 
ATOM   4582  H HD12   . LEU A 1 294 ? -17.810 4.748   -30.879 1.00 23.37  ? 294 LEU A HD12   1 
ATOM   4583  H HD13   . LEU A 1 294 ? -16.844 3.694   -30.185 1.00 23.37  ? 294 LEU A HD13   1 
ATOM   4584  H HD21   . LEU A 1 294 ? -18.377 3.549   -27.555 1.00 27.04  ? 294 LEU A HD21   1 
ATOM   4585  H HD22   . LEU A 1 294 ? -16.796 3.562   -27.694 1.00 27.04  ? 294 LEU A HD22   1 
ATOM   4586  H HD23   . LEU A 1 294 ? -17.533 4.666   -26.821 1.00 27.04  ? 294 LEU A HD23   1 
ATOM   4587  N N      . ALA A 1 295 ? -14.257 7.424   -27.049 1.00 16.95  ? 295 ALA A N      1 
ATOM   4588  C CA     . ALA A 1 295 ? -12.895 7.859   -27.302 1.00 15.28  ? 295 ALA A CA     1 
ATOM   4589  C C      . ALA A 1 295 ? -12.458 7.394   -28.693 1.00 15.10  ? 295 ALA A C      1 
ATOM   4590  O O      . ALA A 1 295 ? -12.915 6.358   -29.205 1.00 14.59  ? 295 ALA A O      1 
ATOM   4591  C CB     . ALA A 1 295 ? -11.950 7.317   -26.230 1.00 16.43  ? 295 ALA A CB     1 
ATOM   4592  H H      . ALA A 1 295 ? -14.338 6.881   -26.387 1.00 20.35  ? 295 ALA A H      1 
ATOM   4593  H HA     . ALA A 1 295 ? -12.858 8.828   -27.279 1.00 18.34  ? 295 ALA A HA     1 
ATOM   4594  H HB1    . ALA A 1 295 ? -11.049 7.621   -26.421 1.00 19.72  ? 295 ALA A HB1    1 
ATOM   4595  H HB2    . ALA A 1 295 ? -12.234 7.647   -25.363 1.00 19.72  ? 295 ALA A HB2    1 
ATOM   4596  H HB3    . ALA A 1 295 ? -11.982 6.348   -26.242 1.00 19.72  ? 295 ALA A HB3    1 
ATOM   4597  N N      . GLY A 1 296 ? -11.559 8.156   -29.299 1.00 14.64  ? 296 GLY A N      1 
ATOM   4598  C CA     . GLY A 1 296 ? -11.026 7.807   -30.599 1.00 15.04  ? 296 GLY A CA     1 
ATOM   4599  C C      . GLY A 1 296 ? -10.420 6.422   -30.597 1.00 13.18  ? 296 GLY A C      1 
ATOM   4600  O O      . GLY A 1 296 ? -10.618 5.639   -31.532 1.00 14.45  ? 296 GLY A O      1 
ATOM   4601  H H      . GLY A 1 296 ? -11.241 8.886   -28.973 1.00 17.57  ? 296 GLY A H      1 
ATOM   4602  H HA2    . GLY A 1 296 ? -11.735 7.834   -31.260 1.00 18.05  ? 296 GLY A HA2    1 
ATOM   4603  H HA3    . GLY A 1 296 ? -10.341 8.445   -30.852 1.00 18.05  ? 296 GLY A HA3    1 
ATOM   4604  N N      . ARG A 1 297 ? -9.699  6.097   -29.528 1.00 14.71  ? 297 ARG A N      1 
ATOM   4605  C CA     . ARG A 1 297 ? -9.066  4.790   -29.442 1.00 14.74  ? 297 ARG A CA     1 
ATOM   4606  C C      . ARG A 1 297 ? -10.090 3.657   -29.482 1.00 18.51  ? 297 ARG A C      1 
ATOM   4607  O O      . ARG A 1 297 ? -9.781  2.567   -29.961 1.00 18.34  ? 297 ARG A O      1 
ATOM   4608  C CB     . ARG A 1 297 ? -8.212  4.684   -28.171 1.00 15.85  ? 297 ARG A CB     1 
ATOM   4609  C CG     . ARG A 1 297 ? -8.939  5.014   -26.904 1.00 16.81  ? 297 ARG A CG     1 
ATOM   4610  C CD     . ARG A 1 297 ? -8.108  4.696   -25.675 1.00 18.24  ? 297 ARG A CD     1 
ATOM   4611  N NE     . ARG A 1 297 ? -8.863  5.025   -24.473 1.00 16.98  ? 297 ARG A NE     1 
ATOM   4612  C CZ     . ARG A 1 297 ? -8.799  6.189   -23.833 1.00 19.12  ? 297 ARG A CZ     1 
ATOM   4613  N NH1    . ARG A 1 297 ? -7.975  7.148   -24.249 1.00 17.10  ? 297 ARG A NH1    1 
ATOM   4614  N NH2    . ARG A 1 297 ? -9.563  6.383   -22.762 1.00 18.61  ? 297 ARG A NH2    1 
ATOM   4615  H H      . ARG A 1 297 ? -9.563  6.609   -28.851 1.00 17.65  ? 297 ARG A H      1 
ATOM   4616  H HA     . ARG A 1 297 ? -8.476  4.680   -30.204 1.00 17.68  ? 297 ARG A HA     1 
ATOM   4617  H HB2    . ARG A 1 297 ? -7.884  3.775   -28.093 1.00 19.02  ? 297 ARG A HB2    1 
ATOM   4618  H HB3    . ARG A 1 297 ? -7.463  5.296   -28.248 1.00 19.02  ? 297 ARG A HB3    1 
ATOM   4619  H HG2    . ARG A 1 297 ? -9.145  5.962   -26.891 1.00 20.18  ? 297 ARG A HG2    1 
ATOM   4620  H HG3    . ARG A 1 297 ? -9.756  4.493   -26.859 1.00 20.18  ? 297 ARG A HG3    1 
ATOM   4621  H HD2    . ARG A 1 297 ? -7.912  3.746   -25.659 1.00 21.88  ? 297 ARG A HD2    1 
ATOM   4622  H HD3    . ARG A 1 297 ? -7.285  5.207   -25.692 1.00 21.88  ? 297 ARG A HD3    1 
ATOM   4623  H HE     . ARG A 1 297 ? -9.388  4.423   -24.155 1.00 20.38  ? 297 ARG A HE     1 
ATOM   4624  H HH11   . ARG A 1 297 ? -7.486  7.032   -24.945 1.00 20.52  ? 297 ARG A HH11   1 
ATOM   4625  H HH12   . ARG A 1 297 ? -7.939  7.894   -23.823 1.00 20.52  ? 297 ARG A HH12   1 
ATOM   4626  H HH21   . ARG A 1 297 ? -10.088 5.759   -22.489 1.00 22.33  ? 297 ARG A HH21   1 
ATOM   4627  H HH22   . ARG A 1 297 ? -9.518  7.126   -22.331 1.00 22.33  ? 297 ARG A HH22   1 
ATOM   4628  N N      . ASP A 1 298 ? -11.303 3.896   -28.996 1.00 13.52  ? 298 ASP A N      1 
ATOM   4629  C CA     . ASP A 1 298 ? -12.325 2.839   -29.022 1.00 15.01  ? 298 ASP A CA     1 
ATOM   4630  C C      . ASP A 1 298 ? -13.016 2.703   -30.373 1.00 18.74  ? 298 ASP A C      1 
ATOM   4631  O O      . ASP A 1 298 ? -13.354 1.580   -30.783 1.00 16.24  ? 298 ASP A O      1 
ATOM   4632  C CB     . ASP A 1 298 ? -13.331 3.080   -27.915 1.00 18.84  ? 298 ASP A CB     1 
ATOM   4633  C CG     . ASP A 1 298 ? -12.735 2.776   -26.553 1.00 25.66  ? 298 ASP A CG     1 
ATOM   4634  O OD1    . ASP A 1 298 ? -12.216 1.649   -26.376 1.00 23.47  ? 298 ASP A OD1    1 
ATOM   4635  O OD2    . ASP A 1 298 ? -12.720 3.672   -25.687 1.00 24.26  ? 298 ASP A OD2    1 
ATOM   4636  H H      . ASP A 1 298 ? -11.561 4.641   -28.652 1.00 16.23  ? 298 ASP A H      1 
ATOM   4637  H HA     . ASP A 1 298 ? -11.895 1.990   -28.837 1.00 18.02  ? 298 ASP A HA     1 
ATOM   4638  H HB2    . ASP A 1 298 ? -13.604 4.011   -27.927 1.00 22.61  ? 298 ASP A HB2    1 
ATOM   4639  H HB3    . ASP A 1 298 ? -14.099 2.502   -28.048 1.00 22.61  ? 298 ASP A HB3    1 
ATOM   4640  N N      . MET A 1 299 ? -13.201 3.812   -31.086 1.00 16.01  ? 299 MET A N      1 
ATOM   4641  C CA     . MET A 1 299 ? -13.625 3.723   -32.484 1.00 15.41  ? 299 MET A CA     1 
ATOM   4642  C C      . MET A 1 299 ? -12.609 2.896   -33.274 1.00 16.42  ? 299 MET A C      1 
ATOM   4643  O O      . MET A 1 299 ? -12.985 2.093   -34.130 1.00 16.26  ? 299 MET A O      1 
ATOM   4644  C CB     . MET A 1 299 ? -13.784 5.113   -33.111 1.00 17.45  ? 299 MET A CB     1 
ATOM   4645  C CG     . MET A 1 299 ? -15.008 5.865   -32.598 1.00 18.42  ? 299 MET A CG     1 
ATOM   4646  S SD     . MET A 1 299 ? -15.348 7.388   -33.509 1.00 18.22  ? 299 MET A SD     1 
ATOM   4647  C CE     . MET A 1 299 ? -13.997 8.431   -32.976 1.00 16.36  ? 299 MET A CE     1 
ATOM   4648  H H      . MET A 1 299 ? -13.091 4.613   -30.793 1.00 19.21  ? 299 MET A H      1 
ATOM   4649  H HA     . MET A 1 299 ? -14.487 3.280   -32.522 1.00 18.49  ? 299 MET A HA     1 
ATOM   4650  H HB2    . MET A 1 299 ? -12.999 5.644   -32.904 1.00 20.94  ? 299 MET A HB2    1 
ATOM   4651  H HB3    . MET A 1 299 ? -13.874 5.016   -34.072 1.00 20.94  ? 299 MET A HB3    1 
ATOM   4652  H HG2    . MET A 1 299 ? -15.786 5.290   -32.677 1.00 22.11  ? 299 MET A HG2    1 
ATOM   4653  H HG3    . MET A 1 299 ? -14.865 6.100   -31.668 1.00 22.11  ? 299 MET A HG3    1 
ATOM   4654  H HE1    . MET A 1 299 ? -14.077 9.296   -33.408 1.00 19.63  ? 299 MET A HE1    1 
ATOM   4655  H HE2    . MET A 1 299 ? -14.041 8.537   -32.013 1.00 19.63  ? 299 MET A HE2    1 
ATOM   4656  H HE3    . MET A 1 299 ? -13.158 8.012   -33.225 1.00 19.63  ? 299 MET A HE3    1 
ATOM   4657  N N      . GLU A 1 300 ? -11.326 3.097   -32.982 1.00 14.63  ? 300 GLU A N      1 
ATOM   4658  C CA     . GLU A 1 300 ? -10.253 2.359   -33.650 1.00 16.62  ? 300 GLU A CA     1 
ATOM   4659  C C      . GLU A 1 300 ? -10.295 0.878   -33.304 1.00 15.62  ? 300 GLU A C      1 
ATOM   4660  O O      . GLU A 1 300 ? -10.219 0.027   -34.194 1.00 15.27  ? 300 GLU A O      1 
ATOM   4661  C CB     . GLU A 1 300 ? -8.884  2.937   -33.274 1.00 15.36  ? 300 GLU A CB     1 
ATOM   4662  C CG     . GLU A 1 300 ? -7.702  2.328   -34.038 1.00 18.17  ? 300 GLU A CG     1 
ATOM   4663  C CD     . GLU A 1 300 ? -7.714  2.645   -35.538 1.00 26.37  ? 300 GLU A CD     1 
ATOM   4664  O OE1    . GLU A 1 300 ? -8.251  3.700   -35.941 1.00 20.88  ? 300 GLU A OE1    1 
ATOM   4665  O OE2    . GLU A 1 300 ? -7.178  1.831   -36.323 1.00 24.44  ? 300 GLU A OE2    1 
ATOM   4666  H H      . GLU A 1 300 ? -11.047 3.661   -32.395 1.00 17.55  ? 300 GLU A H      1 
ATOM   4667  H HA     . GLU A 1 300 ? -10.362 2.445   -34.610 1.00 19.94  ? 300 GLU A HA     1 
ATOM   4668  H HB2    . GLU A 1 300 ? -8.891  3.890   -33.450 1.00 18.43  ? 300 GLU A HB2    1 
ATOM   4669  H HB3    . GLU A 1 300 ? -8.732  2.782   -32.329 1.00 18.43  ? 300 GLU A HB3    1 
ATOM   4670  H HG2    . GLU A 1 300 ? -6.877  2.680   -33.668 1.00 21.80  ? 300 GLU A HG2    1 
ATOM   4671  H HG3    . GLU A 1 300 ? -7.721  1.364   -33.937 1.00 21.80  ? 300 GLU A HG3    1 
ATOM   4672  N N      . ALA A 1 301 ? -10.428 0.564   -32.016 1.00 13.54  ? 301 ALA A N      1 
ATOM   4673  C CA     . ALA A 1 301 ? -10.444 -0.838  -31.586 1.00 14.36  ? 301 ALA A CA     1 
ATOM   4674  C C      . ALA A 1 301 ? -11.644 -1.589  -32.166 1.00 16.08  ? 301 ALA A C      1 
ATOM   4675  O O      . ALA A 1 301 ? -11.546 -2.779  -32.491 1.00 14.26  ? 301 ALA A O      1 
ATOM   4676  C CB     . ALA A 1 301 ? -10.455 -0.927  -30.067 1.00 16.24  ? 301 ALA A CB     1 
ATOM   4677  H H      . ALA A 1 301 ? -10.510 1.134   -31.377 1.00 16.25  ? 301 ALA A H      1 
ATOM   4678  H HA     . ALA A 1 301 ? -9.638  -1.273  -31.904 1.00 17.24  ? 301 ALA A HA     1 
ATOM   4679  H HB1    . ALA A 1 301 ? -10.465 -1.861  -29.806 1.00 19.49  ? 301 ALA A HB1    1 
ATOM   4680  H HB2    . ALA A 1 301 ? -9.659  -0.495  -29.720 1.00 19.49  ? 301 ALA A HB2    1 
ATOM   4681  H HB3    . ALA A 1 301 ? -11.248 -0.480  -29.731 1.00 19.49  ? 301 ALA A HB3    1 
ATOM   4682  N N      . MET A 1 302 ? -12.774 -0.894  -32.282 1.00 14.00  ? 302 MET A N      1 
ATOM   4683  C CA     . MET A 1 302 ? -13.991 -1.504  -32.804 1.00 14.91  ? 302 MET A CA     1 
ATOM   4684  C C      . MET A 1 302 ? -13.852 -1.732  -34.310 1.00 16.92  ? 302 MET A C      1 
ATOM   4685  O O      . MET A 1 302 ? -14.260 -2.769  -34.824 1.00 16.37  ? 302 MET A O      1 
ATOM   4686  C CB     . MET A 1 302 ? -15.209 -0.629  -32.470 1.00 14.99  ? 302 MET A CB     1 
ATOM   4687  C CG     . MET A 1 302 ? -16.556 -1.229  -32.871 1.00 18.41  ? 302 MET A CG     1 
ATOM   4688  S SD     . MET A 1 302 ? -17.948 -0.443  -32.017 1.00 19.94  ? 302 MET A SD     1 
ATOM   4689  C CE     . MET A 1 302 ? -17.710 1.274   -32.473 1.00 16.68  ? 302 MET A CE     1 
ATOM   4690  H H      . MET A 1 302 ? -12.861 -0.066  -32.065 1.00 16.80  ? 302 MET A H      1 
ATOM   4691  H HA     . MET A 1 302 ? -14.120 -2.363  -32.373 1.00 17.89  ? 302 MET A HA     1 
ATOM   4692  H HB2    . MET A 1 302 ? -15.228 -0.478  -31.512 1.00 17.99  ? 302 MET A HB2    1 
ATOM   4693  H HB3    . MET A 1 302 ? -15.116 0.219   -32.932 1.00 17.99  ? 302 MET A HB3    1 
ATOM   4694  H HG2    . MET A 1 302 ? -16.684 -1.111  -33.825 1.00 22.09  ? 302 MET A HG2    1 
ATOM   4695  H HG3    . MET A 1 302 ? -16.561 -2.173  -32.648 1.00 22.09  ? 302 MET A HG3    1 
ATOM   4696  H HE1    . MET A 1 302 ? -18.440 1.800   -32.111 1.00 20.02  ? 302 MET A HE1    1 
ATOM   4697  H HE2    . MET A 1 302 ? -16.866 1.584   -32.108 1.00 20.02  ? 302 MET A HE2    1 
ATOM   4698  H HE3    . MET A 1 302 ? -17.699 1.345   -33.440 1.00 20.02  ? 302 MET A HE3    1 
ATOM   4699  N N      . ALA A 1 303 ? -13.261 -0.778  -35.019 1.00 16.61  ? 303 ALA A N      1 
ATOM   4700  C CA     . ALA A 1 303 ? -13.020 -0.947  -36.448 1.00 15.40  ? 303 ALA A CA     1 
ATOM   4701  C C      . ALA A 1 303 ? -12.163 -2.177  -36.708 1.00 18.95  ? 303 ALA A C      1 
ATOM   4702  O O      . ALA A 1 303 ? -12.469 -2.991  -37.583 1.00 17.21  ? 303 ALA A O      1 
ATOM   4703  C CB     . ALA A 1 303 ? -12.350 0.278   -37.023 1.00 17.89  ? 303 ALA A CB     1 
ATOM   4704  H H      . ALA A 1 303 ? -12.991 -0.027  -34.700 1.00 19.93  ? 303 ALA A H      1 
ATOM   4705  H HA     . ALA A 1 303 ? -13.869 -1.068  -36.902 1.00 18.47  ? 303 ALA A HA     1 
ATOM   4706  H HB1    . ALA A 1 303 ? -12.247 0.163   -37.981 1.00 21.47  ? 303 ALA A HB1    1 
ATOM   4707  H HB2    . ALA A 1 303 ? -12.902 1.054   -36.839 1.00 21.47  ? 303 ALA A HB2    1 
ATOM   4708  H HB3    . ALA A 1 303 ? -11.481 0.386   -36.606 1.00 21.47  ? 303 ALA A HB3    1 
ATOM   4709  N N      . ILE A 1 304 ? -11.097 -2.314  -35.927 1.00 14.18  ? 304 ILE A N      1 
ATOM   4710  C CA     . ILE A 1 304 ? -10.173 -3.431  -36.091 1.00 15.22  ? 304 ILE A CA     1 
ATOM   4711  C C      . ILE A 1 304 ? -10.860 -4.744  -35.708 1.00 15.20  ? 304 ILE A C      1 
ATOM   4712  O O      . ILE A 1 304 ? -10.721 -5.760  -36.403 1.00 15.60  ? 304 ILE A O      1 
ATOM   4713  C CB     . ILE A 1 304 ? -8.901  -3.237  -35.245 1.00 13.96  ? 304 ILE A CB     1 
ATOM   4714  C CG1    . ILE A 1 304 ? -8.135  -1.993  -35.710 1.00 16.89  ? 304 ILE A CG1    1 
ATOM   4715  C CG2    . ILE A 1 304 ? -7.977  -4.447  -35.367 1.00 15.31  ? 304 ILE A CG2    1 
ATOM   4716  C CD1    . ILE A 1 304 ? -7.024  -1.551  -34.767 1.00 16.34  ? 304 ILE A CD1    1 
ATOM   4717  H H      . ILE A 1 304 ? -10.886 -1.773  -35.293 1.00 17.01  ? 304 ILE A H      1 
ATOM   4718  H HA     . ILE A 1 304 ? -9.909  -3.490  -37.022 1.00 18.26  ? 304 ILE A HA     1 
ATOM   4719  H HB     . ILE A 1 304 ? -9.153  -3.124  -34.315 1.00 16.75  ? 304 ILE A HB     1 
ATOM   4720  H HG12   . ILE A 1 304 ? -7.730  -2.183  -36.571 1.00 20.27  ? 304 ILE A HG12   1 
ATOM   4721  H HG13   . ILE A 1 304 ? -8.757  -1.255  -35.800 1.00 20.27  ? 304 ILE A HG13   1 
ATOM   4722  H HG21   . ILE A 1 304 ? -7.121  -4.237  -34.962 1.00 18.37  ? 304 ILE A HG21   1 
ATOM   4723  H HG22   . ILE A 1 304 ? -8.377  -5.202  -34.909 1.00 18.37  ? 304 ILE A HG22   1 
ATOM   4724  H HG23   . ILE A 1 304 ? -7.854  -4.655  -36.306 1.00 18.37  ? 304 ILE A HG23   1 
ATOM   4725  H HD11   . ILE A 1 304 ? -6.728  -0.663  -35.023 1.00 19.60  ? 304 ILE A HD11   1 
ATOM   4726  H HD12   . ILE A 1 304 ? -7.368  -1.536  -33.860 1.00 19.60  ? 304 ILE A HD12   1 
ATOM   4727  H HD13   . ILE A 1 304 ? -6.286  -2.177  -34.830 1.00 19.60  ? 304 ILE A HD13   1 
ATOM   4728  N N      . GLY A 1 305 ? -11.612 -4.708  -34.613 1.00 13.52  ? 305 GLY A N      1 
ATOM   4729  C CA     . GLY A 1 305 ? -12.262 -5.896  -34.087 1.00 16.10  ? 305 GLY A CA     1 
ATOM   4730  C C      . GLY A 1 305 ? -13.294 -6.477  -35.035 1.00 17.35  ? 305 GLY A C      1 
ATOM   4731  O O      . GLY A 1 305 ? -13.396 -7.699  -35.181 1.00 16.47  ? 305 GLY A O      1 
ATOM   4732  H H      . GLY A 1 305 ? -11.761 -3.997  -34.153 1.00 16.23  ? 305 GLY A H      1 
ATOM   4733  H HA2    . GLY A 1 305 ? -11.593 -6.576  -33.912 1.00 19.32  ? 305 GLY A HA2    1 
ATOM   4734  H HA3    . GLY A 1 305 ? -12.698 -5.676  -33.251 1.00 19.32  ? 305 GLY A HA3    1 
ATOM   4735  N N      . LEU A 1 306 ? -14.078 -5.606  -35.663 1.00 16.47  ? 306 LEU A N      1 
ATOM   4736  C CA     . LEU A 1 306 ? -15.106 -6.055  -36.606 1.00 17.91  ? 306 LEU A CA     1 
ATOM   4737  C C      . LEU A 1 306 ? -14.459 -6.787  -37.770 1.00 16.94  ? 306 LEU A C      1 
ATOM   4738  O O      . LEU A 1 306 ? -14.951 -7.831  -38.216 1.00 17.49  ? 306 LEU A O      1 
ATOM   4739  C CB     . LEU A 1 306 ? -15.943 -4.878  -37.122 1.00 19.39  ? 306 LEU A CB     1 
ATOM   4740  C CG     . LEU A 1 306 ? -17.081 -5.245  -38.087 1.00 21.64  ? 306 LEU A CG     1 
ATOM   4741  C CD1    . LEU A 1 306 ? -18.060 -6.252  -37.470 1.00 25.06  ? 306 LEU A CD1    1 
ATOM   4742  C CD2    . LEU A 1 306 ? -17.826 -3.996  -38.528 1.00 24.15  ? 306 LEU A CD2    1 
ATOM   4743  H H      . LEU A 1 306 ? -14.038 -4.753  -35.563 1.00 19.77  ? 306 LEU A H      1 
ATOM   4744  H HA     . LEU A 1 306 ? -15.699 -6.674  -36.153 1.00 21.50  ? 306 LEU A HA     1 
ATOM   4745  H HB2    . LEU A 1 306 ? -16.342 -4.428  -36.360 1.00 23.26  ? 306 LEU A HB2    1 
ATOM   4746  H HB3    . LEU A 1 306 ? -15.354 -4.264  -37.588 1.00 23.26  ? 306 LEU A HB3    1 
ATOM   4747  H HG     . LEU A 1 306 ? -16.699 -5.653  -38.879 1.00 25.97  ? 306 LEU A HG     1 
ATOM   4748  H HD11   . LEU A 1 306 ? -18.805 -6.379  -38.078 1.00 30.08  ? 306 LEU A HD11   1 
ATOM   4749  H HD12   . LEU A 1 306 ? -17.601 -7.095  -37.330 1.00 30.08  ? 306 LEU A HD12   1 
ATOM   4750  H HD13   . LEU A 1 306 ? -18.380 -5.903  -36.624 1.00 30.08  ? 306 LEU A HD13   1 
ATOM   4751  H HD21   . LEU A 1 306 ? -18.537 -4.251  -39.137 1.00 28.98  ? 306 LEU A HD21   1 
ATOM   4752  H HD22   . LEU A 1 306 ? -18.200 -3.559  -37.747 1.00 28.98  ? 306 LEU A HD22   1 
ATOM   4753  H HD23   . LEU A 1 306 ? -17.205 -3.400  -38.975 1.00 28.98  ? 306 LEU A HD23   1 
ATOM   4754  N N      . ARG A 1 307 ? -13.349 -6.251  -38.261 1.00 16.42  ? 307 ARG A N      1 
ATOM   4755  C CA     . ARG A 1 307 ? -12.628 -6.922  -39.334 1.00 21.50  ? 307 ARG A CA     1 
ATOM   4756  C C      . ARG A 1 307 ? -12.045 -8.263  -38.859 1.00 19.95  ? 307 ARG A C      1 
ATOM   4757  O O      . ARG A 1 307 ? -12.072 -9.243  -39.601 1.00 18.80  ? 307 ARG A O      1 
ATOM   4758  C CB     . ARG A 1 307 ? -11.530 -6.013  -39.891 1.00 21.16  ? 307 ARG A CB     1 
ATOM   4759  C CG     . ARG A 1 307 ? -10.954 -6.504  -41.196 1.00 29.12  ? 307 ARG A CG     1 
ATOM   4760  C CD     . ARG A 1 307 ? -10.035 -5.477  -41.848 1.00 31.97  ? 307 ARG A CD     1 
ATOM   4761  N NE     . ARG A 1 307 ? -10.702 -4.215  -42.186 1.00 31.55  ? 307 ARG A NE     1 
ATOM   4762  C CZ     . ARG A 1 307 ? -11.403 -3.998  -43.301 1.00 33.15  ? 307 ARG A CZ     1 
ATOM   4763  N NH1    . ARG A 1 307 ? -11.575 -4.963  -44.196 1.00 30.55  ? 307 ARG A NH1    1 
ATOM   4764  N NH2    . ARG A 1 307 ? -11.955 -2.811  -43.519 1.00 31.49  ? 307 ARG A NH2    1 
ATOM   4765  H H      . ARG A 1 307 ? -12.997 -5.512  -37.996 1.00 19.70  ? 307 ARG A H      1 
ATOM   4766  H HA     . ARG A 1 307 ? -13.248 -7.110  -40.056 1.00 25.81  ? 307 ARG A HA     1 
ATOM   4767  H HB2    . ARG A 1 307 ? -11.901 -5.130  -40.042 1.00 25.39  ? 307 ARG A HB2    1 
ATOM   4768  H HB3    . ARG A 1 307 ? -10.808 -5.962  -39.246 1.00 25.39  ? 307 ARG A HB3    1 
ATOM   4769  H HG2    . ARG A 1 307 ? -10.438 -7.309  -41.032 1.00 34.94  ? 307 ARG A HG2    1 
ATOM   4770  H HG3    . ARG A 1 307 ? -11.679 -6.693  -41.812 1.00 34.94  ? 307 ARG A HG3    1 
ATOM   4771  H HD2    . ARG A 1 307 ? -9.312  -5.273  -41.234 1.00 38.36  ? 307 ARG A HD2    1 
ATOM   4772  H HD3    . ARG A 1 307 ? -9.673  -5.853  -42.665 1.00 38.36  ? 307 ARG A HD3    1 
ATOM   4773  H HE     . ARG A 1 307 ? -10.637 -3.567  -41.624 1.00 37.86  ? 307 ARG A HE     1 
ATOM   4774  H HH11   . ARG A 1 307 ? -11.222 -5.737  -44.072 1.00 36.66  ? 307 ARG A HH11   1 
ATOM   4775  H HH12   . ARG A 1 307 ? -12.034 -4.811  -44.907 1.00 36.66  ? 307 ARG A HH12   1 
ATOM   4776  H HH21   . ARG A 1 307 ? -11.857 -2.179  -42.944 1.00 37.79  ? 307 ARG A HH21   1 
ATOM   4777  H HH22   . ARG A 1 307 ? -12.416 -2.676  -44.232 1.00 37.79  ? 307 ARG A HH22   1 
ATOM   4778  N N      . GLU A 1 308 ? -11.537 -8.323  -37.628 1.00 17.81  ? 308 GLU A N      1 
ATOM   4779  C CA     . GLU A 1 308 ? -11.027 -9.585  -37.078 1.00 16.19  ? 308 GLU A CA     1 
ATOM   4780  C C      . GLU A 1 308 ? -12.126 -10.648 -36.967 1.00 14.49  ? 308 GLU A C      1 
ATOM   4781  O O      . GLU A 1 308 ? -11.880 -11.840 -37.186 1.00 16.18  ? 308 GLU A O      1 
ATOM   4782  C CB     . GLU A 1 308 ? -10.387 -9.369  -35.694 1.00 17.00  ? 308 GLU A CB     1 
ATOM   4783  C CG     . GLU A 1 308 ? -9.062  -8.631  -35.750 1.00 19.68  ? 308 GLU A CG     1 
ATOM   4784  C CD     . GLU A 1 308 ? -8.338  -8.537  -34.415 1.00 20.14  ? 308 GLU A CD     1 
ATOM   4785  O OE1    . GLU A 1 308 ? -8.819  -9.096  -33.391 1.00 17.53  ? 308 GLU A OE1    1 
ATOM   4786  O OE2    . GLU A 1 308 ? -7.257  -7.908  -34.400 1.00 19.96  ? 308 GLU A OE2    1 
ATOM   4787  H H      . GLU A 1 308 ? -11.475 -7.653  -37.092 1.00 21.37  ? 308 GLU A H      1 
ATOM   4788  H HA     . GLU A 1 308 ? -10.341 -9.929  -37.671 1.00 19.43  ? 308 GLU A HA     1 
ATOM   4789  H HB2    . GLU A 1 308 ? -10.994 -8.849  -35.145 1.00 20.40  ? 308 GLU A HB2    1 
ATOM   4790  H HB3    . GLU A 1 308 ? -10.229 -10.234 -35.284 1.00 20.40  ? 308 GLU A HB3    1 
ATOM   4791  H HG2    . GLU A 1 308 ? -8.476  -9.094  -36.369 1.00 23.62  ? 308 GLU A HG2    1 
ATOM   4792  H HG3    . GLU A 1 308 ? -9.220  -7.728  -36.064 1.00 23.62  ? 308 GLU A HG3    1 
ATOM   4793  N N      . ALA A 1 309 ? -13.333 -10.208 -36.633 1.00 17.12  ? 309 ALA A N      1 
ATOM   4794  C CA     . ALA A 1 309 ? -14.469 -11.107 -36.436 1.00 17.69  ? 309 ALA A CA     1 
ATOM   4795  C C      . ALA A 1 309 ? -14.842 -11.854 -37.722 1.00 19.73  ? 309 ALA A C      1 
ATOM   4796  O O      . ALA A 1 309 ? -15.448 -12.926 -37.655 1.00 19.74  ? 309 ALA A O      1 
ATOM   4797  C CB     . ALA A 1 309 ? -15.659 -10.329 -35.918 1.00 18.94  ? 309 ALA A CB     1 
ATOM   4798  H H      . ALA A 1 309 ? -13.525 -9.379  -36.512 1.00 20.54  ? 309 ALA A H      1 
ATOM   4799  H HA     . ALA A 1 309 ? -14.232 -11.768 -35.767 1.00 21.23  ? 309 ALA A HA     1 
ATOM   4800  H HB1    . ALA A 1 309 ? -16.402 -10.939 -35.789 1.00 22.73  ? 309 ALA A HB1    1 
ATOM   4801  H HB2    . ALA A 1 309 ? -15.421 -9.913  -35.074 1.00 22.73  ? 309 ALA A HB2    1 
ATOM   4802  H HB3    . ALA A 1 309 ? -15.898 -9.649  -36.567 1.00 22.73  ? 309 ALA A HB3    1 
ATOM   4803  N N      . MET A 1 310 ? -14.464 -11.306 -38.879 1.00 17.17  ? 310 MET A N      1 
ATOM   4804  C CA     . MET A 1 310 ? -14.757 -11.945 -40.167 1.00 19.22  ? 310 MET A CA     1 
ATOM   4805  C C      . MET A 1 310 ? -13.896 -13.183 -40.441 1.00 19.24  ? 310 MET A C      1 
ATOM   4806  O O      . MET A 1 310 ? -14.172 -13.913 -41.398 1.00 21.24  ? 310 MET A O      1 
ATOM   4807  C CB     . MET A 1 310 ? -14.552 -10.976 -41.341 1.00 20.58  ? 310 MET A CB     1 
ATOM   4808  C CG     . MET A 1 310 ? -15.281 -9.637  -41.271 1.00 24.48  ? 310 MET A CG     1 
ATOM   4809  S SD     . MET A 1 310 ? -17.082 -9.734  -41.435 1.00 26.42  ? 310 MET A SD     1 
ATOM   4810  C CE     . MET A 1 310 ? -17.612 -9.676  -39.729 1.00 25.91  ? 310 MET A CE     1 
ATOM   4811  H H      . MET A 1 310 ? -14.036 -10.563 -38.947 1.00 20.61  ? 310 MET A H      1 
ATOM   4812  H HA     . MET A 1 310 ? -15.689 -12.213 -40.170 1.00 23.06  ? 310 MET A HA     1 
ATOM   4813  H HB2    . MET A 1 310 ? -13.604 -10.782 -41.409 1.00 24.70  ? 310 MET A HB2    1 
ATOM   4814  H HB3    . MET A 1 310 ? -14.846 -11.419 -42.152 1.00 24.70  ? 310 MET A HB3    1 
ATOM   4815  H HG2    . MET A 1 310 ? -15.087 -9.225  -40.415 1.00 29.38  ? 310 MET A HG2    1 
ATOM   4816  H HG3    . MET A 1 310 ? -14.953 -9.070  -41.986 1.00 29.38  ? 310 MET A HG3    1 
ATOM   4817  H HE1    . MET A 1 310 ? -18.580 -9.721  -39.698 1.00 31.09  ? 310 MET A HE1    1 
ATOM   4818  H HE2    . MET A 1 310 ? -17.230 -10.431 -39.254 1.00 31.09  ? 310 MET A HE2    1 
ATOM   4819  H HE3    . MET A 1 310 ? -17.306 -8.846  -39.332 1.00 31.09  ? 310 MET A HE3    1 
ATOM   4820  N N      . GLN A 1 311 ? -12.835 -13.396 -39.663 1.00 19.11  ? 311 GLN A N      1 
ATOM   4821  C CA     . GLN A 1 311 ? -11.955 -14.542 -39.898 1.00 17.86  ? 311 GLN A CA     1 
ATOM   4822  C C      . GLN A 1 311 ? -12.731 -15.819 -39.589 1.00 20.15  ? 311 GLN A C      1 
ATOM   4823  O O      . GLN A 1 311 ? -13.236 -15.985 -38.476 1.00 16.77  ? 311 GLN A O      1 
ATOM   4824  C CB     . GLN A 1 311 ? -10.675 -14.473 -39.046 1.00 18.93  ? 311 GLN A CB     1 
ATOM   4825  C CG     . GLN A 1 311 ? -9.696  -15.642 -39.315 1.00 22.98  ? 311 GLN A CG     1 
ATOM   4826  C CD     . GLN A 1 311 ? -8.456  -15.654 -38.419 1.00 26.96  ? 311 GLN A CD     1 
ATOM   4827  O OE1    . GLN A 1 311 ? -8.468  -15.138 -37.302 1.00 25.11  ? 311 GLN A OE1    1 
ATOM   4828  N NE2    . GLN A 1 311 ? -7.376  -16.262 -38.912 1.00 28.24  ? 311 GLN A NE2    1 
ATOM   4829  H H      . GLN A 1 311 ? -12.604 -12.899 -39.000 1.00 22.93  ? 311 GLN A H      1 
ATOM   4830  H HA     . GLN A 1 311 ? -11.697 -14.561 -40.833 1.00 21.44  ? 311 GLN A HA     1 
ATOM   4831  H HB2    . GLN A 1 311 ? -10.211 -13.644 -39.243 1.00 22.72  ? 311 GLN A HB2    1 
ATOM   4832  H HB3    . GLN A 1 311 ? -10.920 -14.499 -38.108 1.00 22.72  ? 311 GLN A HB3    1 
ATOM   4833  H HG2    . GLN A 1 311 ? -10.163 -16.480 -39.176 1.00 27.57  ? 311 GLN A HG2    1 
ATOM   4834  H HG3    . GLN A 1 311 ? -9.393  -15.587 -40.235 1.00 27.57  ? 311 GLN A HG3    1 
ATOM   4835  H HE21   . GLN A 1 311 ? -7.405  -16.626 -39.690 1.00 33.89  ? 311 GLN A HE21   1 
ATOM   4836  H HE22   . GLN A 1 311 ? -6.650  -16.290 -38.451 1.00 33.89  ? 311 GLN A HE22   1 
ATOM   4837  N N      . PHE A 1 312 ? -12.843 -16.709 -40.577 1.00 16.02  ? 312 PHE A N      1 
ATOM   4838  C CA     . PHE A 1 312 ? -13.586 -17.954 -40.379 1.00 16.75  ? 312 PHE A CA     1 
ATOM   4839  C C      . PHE A 1 312 ? -13.114 -18.750 -39.165 1.00 16.33  ? 312 PHE A C      1 
ATOM   4840  O O      . PHE A 1 312 ? -13.928 -19.214 -38.357 1.00 16.22  ? 312 PHE A O      1 
ATOM   4841  C CB     . PHE A 1 312 ? -13.493 -18.860 -41.615 1.00 17.05  ? 312 PHE A CB     1 
ATOM   4842  C CG     . PHE A 1 312 ? -14.085 -20.220 -41.387 1.00 19.31  ? 312 PHE A CG     1 
ATOM   4843  C CD1    . PHE A 1 312 ? -15.457 -20.385 -41.329 1.00 18.36  ? 312 PHE A CD1    1 
ATOM   4844  C CD2    . PHE A 1 312 ? -13.270 -21.320 -41.187 1.00 21.14  ? 312 PHE A CD2    1 
ATOM   4845  C CE1    . PHE A 1 312 ? -16.014 -21.634 -41.102 1.00 19.94  ? 312 PHE A CE1    1 
ATOM   4846  C CE2    . PHE A 1 312 ? -13.820 -22.573 -40.954 1.00 22.85  ? 312 PHE A CE2    1 
ATOM   4847  C CZ     . PHE A 1 312 ? -15.198 -22.722 -40.913 1.00 19.50  ? 312 PHE A CZ     1 
ATOM   4848  H H      . PHE A 1 312 ? -12.503 -16.617 -41.361 1.00 19.22  ? 312 PHE A H      1 
ATOM   4849  H HA     . PHE A 1 312 ? -14.522 -17.737 -40.243 1.00 20.10  ? 312 PHE A HA     1 
ATOM   4850  H HB2    . PHE A 1 312 ? -13.973 -18.444 -42.348 1.00 20.46  ? 312 PHE A HB2    1 
ATOM   4851  H HB3    . PHE A 1 312 ? -12.560 -18.975 -41.853 1.00 20.46  ? 312 PHE A HB3    1 
ATOM   4852  H HD1    . PHE A 1 312 ? -16.013 -19.651 -41.456 1.00 22.03  ? 312 PHE A HD1    1 
ATOM   4853  H HD2    . PHE A 1 312 ? -12.346 -21.220 -41.214 1.00 25.37  ? 312 PHE A HD2    1 
ATOM   4854  H HE1    . PHE A 1 312 ? -16.938 -21.734 -41.073 1.00 23.92  ? 312 PHE A HE1    1 
ATOM   4855  H HE2    . PHE A 1 312 ? -13.267 -23.310 -40.829 1.00 27.42  ? 312 PHE A HE2    1 
ATOM   4856  H HZ     . PHE A 1 312 ? -15.570 -23.561 -40.761 1.00 23.40  ? 312 PHE A HZ     1 
ATOM   4857  N N      . GLU A 1 313 ? -11.807 -18.944 -39.036 1.00 16.09  ? 313 GLU A N      1 
ATOM   4858  C CA     . GLU A 1 313 ? -11.314 -19.806 -37.968 1.00 16.97  ? 313 GLU A CA     1 
ATOM   4859  C C      . GLU A 1 313 ? -11.640 -19.214 -36.601 1.00 16.94  ? 313 GLU A C      1 
ATOM   4860  O O      . GLU A 1 313 ? -11.898 -19.955 -35.653 1.00 15.99  ? 313 GLU A O      1 
ATOM   4861  C CB     . GLU A 1 313 ? -9.809  -20.046 -38.105 1.00 21.85  ? 313 GLU A CB     1 
ATOM   4862  C CG     . GLU A 1 313 ? -9.429  -20.916 -39.308 1.00 24.29  ? 313 GLU A CG     1 
ATOM   4863  C CD     . GLU A 1 313 ? -9.337  -20.138 -40.613 1.00 29.27  ? 313 GLU A CD     1 
ATOM   4864  O OE1    . GLU A 1 313 ? -9.591  -18.912 -40.627 1.00 23.52  ? 313 GLU A OE1    1 
ATOM   4865  O OE2    . GLU A 1 313 ? -9.004  -20.769 -41.635 1.00 30.08  ? 313 GLU A OE2    1 
ATOM   4866  H H      . GLU A 1 313 ? -11.200 -18.599 -39.538 1.00 19.31  ? 313 GLU A H      1 
ATOM   4867  H HA     . GLU A 1 313 ? -11.758 -20.666 -38.031 1.00 20.37  ? 313 GLU A HA     1 
ATOM   4868  H HB2    . GLU A 1 313 ? -9.359  -19.191 -38.193 1.00 26.22  ? 313 GLU A HB2    1 
ATOM   4869  H HB3    . GLU A 1 313 ? -9.495  -20.498 -37.306 1.00 26.22  ? 313 GLU A HB3    1 
ATOM   4870  H HG2    . GLU A 1 313 ? -8.563  -21.321 -39.141 1.00 29.14  ? 313 GLU A HG2    1 
ATOM   4871  H HG3    . GLU A 1 313 ? -10.100 -21.607 -39.420 1.00 29.14  ? 313 GLU A HG3    1 
ATOM   4872  N N      . TYR A 1 314 ? -11.636 -17.886 -36.496 1.00 16.82  ? 314 TYR A N      1 
ATOM   4873  C CA     . TYR A 1 314 ? -12.019 -17.239 -35.241 1.00 15.06  ? 314 TYR A CA     1 
ATOM   4874  C C      . TYR A 1 314 ? -13.480 -17.541 -34.867 1.00 16.14  ? 314 TYR A C      1 
ATOM   4875  O O      . TYR A 1 314 ? -13.747 -18.005 -33.762 1.00 17.46  ? 314 TYR A O      1 
ATOM   4876  C CB     . TYR A 1 314 ? -11.818 -15.709 -35.285 1.00 15.25  ? 314 TYR A CB     1 
ATOM   4877  C CG     . TYR A 1 314 ? -12.791 -15.057 -34.338 1.00 18.08  ? 314 TYR A CG     1 
ATOM   4878  C CD1    . TYR A 1 314 ? -12.636 -15.191 -32.963 1.00 18.05  ? 314 TYR A CD1    1 
ATOM   4879  C CD2    . TYR A 1 314 ? -13.915 -14.405 -34.810 1.00 16.85  ? 314 TYR A CD2    1 
ATOM   4880  C CE1    . TYR A 1 314 ? -13.553 -14.662 -32.091 1.00 19.04  ? 314 TYR A CE1    1 
ATOM   4881  C CE2    . TYR A 1 314 ? -14.841 -13.868 -33.949 1.00 17.47  ? 314 TYR A CE2    1 
ATOM   4882  C CZ     . TYR A 1 314 ? -14.656 -14.000 -32.584 1.00 14.24  ? 314 TYR A CZ     1 
ATOM   4883  O OH     . TYR A 1 314 ? -15.577 -13.474 -31.705 1.00 18.55  ? 314 TYR A OH     1 
ATOM   4884  H H      . TYR A 1 314 ? -11.419 -17.343 -37.127 1.00 20.18  ? 314 TYR A H      1 
ATOM   4885  H HA     . TYR A 1 314 ? -11.457 -17.587 -34.531 1.00 18.07  ? 314 TYR A HA     1 
ATOM   4886  H HB2    . TYR A 1 314 ? -10.916 -15.489 -35.005 1.00 18.30  ? 314 TYR A HB2    1 
ATOM   4887  H HB3    . TYR A 1 314 ? -11.989 -15.382 -36.182 1.00 18.30  ? 314 TYR A HB3    1 
ATOM   4888  H HD1    . TYR A 1 314 ? -11.897 -15.647 -32.629 1.00 21.67  ? 314 TYR A HD1    1 
ATOM   4889  H HD2    . TYR A 1 314 ? -14.045 -14.325 -35.727 1.00 20.22  ? 314 TYR A HD2    1 
ATOM   4890  H HE1    . TYR A 1 314 ? -13.430 -14.749 -31.173 1.00 22.85  ? 314 TYR A HE1    1 
ATOM   4891  H HE2    . TYR A 1 314 ? -15.586 -13.421 -34.281 1.00 20.96  ? 314 TYR A HE2    1 
ATOM   4892  H HH     . TYR A 1 314 ? -15.341 -13.631 -30.914 1.00 22.26  ? 314 TYR A HH     1 
ATOM   4893  N N      . ILE A 1 315 ? -14.437 -17.292 -35.760 1.00 14.73  ? 315 ILE A N      1 
ATOM   4894  C CA     . ILE A 1 315 ? -15.834 -17.377 -35.335 1.00 16.34  ? 315 ILE A CA     1 
ATOM   4895  C C      . ILE A 1 315 ? -16.249 -18.851 -35.236 1.00 16.10  ? 315 ILE A C      1 
ATOM   4896  O O      . ILE A 1 315 ? -17.065 -19.215 -34.384 1.00 15.21  ? 315 ILE A O      1 
ATOM   4897  C CB     . ILE A 1 315 ? -16.771 -16.564 -36.271 1.00 16.81  ? 315 ILE A CB     1 
ATOM   4898  C CG1    . ILE A 1 315 ? -18.189 -16.463 -35.681 1.00 16.54  ? 315 ILE A CG1    1 
ATOM   4899  C CG2    . ILE A 1 315 ? -16.768 -17.120 -37.699 1.00 16.22  ? 315 ILE A CG2    1 
ATOM   4900  C CD1    . ILE A 1 315 ? -18.283 -15.596 -34.419 1.00 18.65  ? 315 ILE A CD1    1 
ATOM   4901  H H      . ILE A 1 315 ? -14.312 -17.080 -36.584 1.00 17.67  ? 315 ILE A H      1 
ATOM   4902  H HA     . ILE A 1 315 ? -15.910 -16.993 -34.448 1.00 19.60  ? 315 ILE A HA     1 
ATOM   4903  H HB     . ILE A 1 315 ? -16.416 -15.662 -36.316 1.00 20.17  ? 315 ILE A HB     1 
ATOM   4904  H HG12   . ILE A 1 315 ? -18.777 -16.078 -36.349 1.00 19.84  ? 315 ILE A HG12   1 
ATOM   4905  H HG13   . ILE A 1 315 ? -18.498 -17.353 -35.451 1.00 19.84  ? 315 ILE A HG13   1 
ATOM   4906  H HG21   . ILE A 1 315 ? -17.316 -16.549 -38.260 1.00 19.47  ? 315 ILE A HG21   1 
ATOM   4907  H HG22   . ILE A 1 315 ? -15.857 -17.133 -38.031 1.00 19.47  ? 315 ILE A HG22   1 
ATOM   4908  H HG23   . ILE A 1 315 ? -17.130 -18.020 -37.690 1.00 19.47  ? 315 ILE A HG23   1 
ATOM   4909  H HD11   . ILE A 1 315 ? -19.217 -15.485 -34.183 1.00 22.38  ? 315 ILE A HD11   1 
ATOM   4910  H HD12   . ILE A 1 315 ? -17.809 -16.036 -33.696 1.00 22.38  ? 315 ILE A HD12   1 
ATOM   4911  H HD13   . ILE A 1 315 ? -17.884 -14.731 -34.600 1.00 22.38  ? 315 ILE A HD13   1 
ATOM   4912  N N      . GLU A 1 316 ? -15.645 -19.698 -36.065 1.00 15.20  ? 316 GLU A N      1 
ATOM   4913  C CA     . GLU A 1 316 ? -15.817 -21.141 -35.953 1.00 19.11  ? 316 GLU A CA     1 
ATOM   4914  C C      . GLU A 1 316 ? -15.428 -21.631 -34.555 1.00 21.55  ? 316 GLU A C      1 
ATOM   4915  O O      . GLU A 1 316 ? -16.198 -22.336 -33.891 1.00 16.42  ? 316 GLU A O      1 
ATOM   4916  C CB     . GLU A 1 316 ? -14.981 -21.877 -37.000 1.00 20.56  ? 316 GLU A CB     1 
ATOM   4917  C CG     . GLU A 1 316 ? -15.232 -23.384 -36.985 1.00 19.50  ? 316 GLU A CG     1 
ATOM   4918  C CD     . GLU A 1 316 ? -14.138 -24.210 -37.650 1.00 24.68  ? 316 GLU A CD     1 
ATOM   4919  O OE1    . GLU A 1 316 ? -12.983 -23.747 -37.762 1.00 22.99  ? 316 GLU A OE1    1 
ATOM   4920  O OE2    . GLU A 1 316 ? -14.448 -25.352 -38.048 1.00 27.86  ? 316 GLU A OE2    1 
ATOM   4921  H H      . GLU A 1 316 ? -15.126 -19.458 -36.707 1.00 18.23  ? 316 GLU A H      1 
ATOM   4922  H HA     . GLU A 1 316 ? -16.750 -21.362 -36.101 1.00 22.93  ? 316 GLU A HA     1 
ATOM   4923  H HB2    . GLU A 1 316 ? -15.209 -21.542 -37.881 1.00 24.67  ? 316 GLU A HB2    1 
ATOM   4924  H HB3    . GLU A 1 316 ? -14.042 -21.721 -36.816 1.00 24.67  ? 316 GLU A HB3    1 
ATOM   4925  H HG2    . GLU A 1 316 ? -15.307 -23.691 -36.070 1.00 23.40  ? 316 GLU A HG2    1 
ATOM   4926  H HG3    . GLU A 1 316 ? -16.061 -23.563 -37.456 1.00 23.40  ? 316 GLU A HG3    1 
ATOM   4927  N N      . HIS A 1 317 ? -14.235 -21.252 -34.108 1.00 15.60  ? 317 HIS A N      1 
ATOM   4928  C CA     . HIS A 1 317 ? -13.792 -21.647 -32.783 1.00 16.90  ? 317 HIS A CA     1 
ATOM   4929  C C      . HIS A 1 317 ? -14.687 -21.051 -31.698 1.00 16.40  ? 317 HIS A C      1 
ATOM   4930  O O      . HIS A 1 317 ? -14.997 -21.731 -30.716 1.00 16.28  ? 317 HIS A O      1 
ATOM   4931  C CB     . HIS A 1 317 ? -12.350 -21.228 -32.516 1.00 16.75  ? 317 HIS A CB     1 
ATOM   4932  C CG     . HIS A 1 317 ? -11.970 -21.351 -31.075 1.00 17.12  ? 317 HIS A CG     1 
ATOM   4933  N ND1    . HIS A 1 317 ? -12.029 -20.285 -30.202 1.00 20.93  ? 317 HIS A ND1    1 
ATOM   4934  C CD2    . HIS A 1 317 ? -11.574 -22.419 -30.344 1.00 18.42  ? 317 HIS A CD2    1 
ATOM   4935  C CE1    . HIS A 1 317 ? -11.666 -20.688 -28.997 1.00 20.16  ? 317 HIS A CE1    1 
ATOM   4936  N NE2    . HIS A 1 317 ? -11.390 -21.979 -29.053 1.00 17.68  ? 317 HIS A NE2    1 
ATOM   4937  H H      . HIS A 1 317 ? -13.672 -20.773 -34.548 1.00 18.72  ? 317 HIS A H      1 
ATOM   4938  H HA     . HIS A 1 317 ? -13.840 -22.613 -32.711 1.00 20.27  ? 317 HIS A HA     1 
ATOM   4939  H HB2    . HIS A 1 317 ? -11.755 -21.794 -33.032 1.00 20.10  ? 317 HIS A HB2    1 
ATOM   4940  H HB3    . HIS A 1 317 ? -12.236 -20.301 -32.778 1.00 20.10  ? 317 HIS A HB3    1 
ATOM   4941  H HD1    . HIS A 1 317 ? -12.259 -19.483 -30.410 1.00 25.11  ? 317 HIS A HD1    1 
ATOM   4942  H HD2    . HIS A 1 317 ? -11.448 -23.286 -30.656 1.00 22.10  ? 317 HIS A HD2    1 
ATOM   4943  H HE1    . HIS A 1 317 ? -11.615 -20.154 -28.237 1.00 24.19  ? 317 HIS A HE1    1 
ATOM   4944  N N      . ARG A 1 318 ? -15.083 -19.786 -31.862 1.00 17.22  ? 318 ARG A N      1 
ATOM   4945  C CA     . ARG A 1 318 ? -15.913 -19.103 -30.866 1.00 16.69  ? 318 ARG A CA     1 
ATOM   4946  C C      . ARG A 1 318 ? -17.170 -19.932 -30.621 1.00 17.04  ? 318 ARG A C      1 
ATOM   4947  O O      . ARG A 1 318 ? -17.456 -20.345 -29.501 1.00 16.72  ? 318 ARG A O      1 
ATOM   4948  C CB     . ARG A 1 318 ? -16.274 -17.680 -31.332 1.00 16.35  ? 318 ARG A CB     1 
ATOM   4949  C CG     . ARG A 1 318 ? -16.959 -16.773 -30.280 1.00 16.73  ? 318 ARG A CG     1 
ATOM   4950  C CD     . ARG A 1 318 ? -18.393 -17.179 -29.982 1.00 18.12  ? 318 ARG A CD     1 
ATOM   4951  N NE     . ARG A 1 318 ? -19.183 -16.175 -29.256 1.00 16.97  ? 318 ARG A NE     1 
ATOM   4952  C CZ     . ARG A 1 318 ? -19.122 -15.965 -27.942 1.00 17.48  ? 318 ARG A CZ     1 
ATOM   4953  N NH1    . ARG A 1 318 ? -18.267 -16.638 -27.191 1.00 16.13  ? 318 ARG A NH1    1 
ATOM   4954  N NH2    . ARG A 1 318 ? -19.903 -15.056 -27.376 1.00 14.47  ? 318 ARG A NH2    1 
ATOM   4955  H H      . ARG A 1 318 ? -14.884 -19.300 -32.543 1.00 20.66  ? 318 ARG A H      1 
ATOM   4956  H HA     . ARG A 1 318 ? -15.424 -19.036 -30.031 1.00 20.02  ? 318 ARG A HA     1 
ATOM   4957  H HB2    . ARG A 1 318 ? -15.458 -17.234 -31.610 1.00 19.62  ? 318 ARG A HB2    1 
ATOM   4958  H HB3    . ARG A 1 318 ? -16.876 -17.750 -32.089 1.00 19.62  ? 318 ARG A HB3    1 
ATOM   4959  H HG2    . ARG A 1 318 ? -16.457 -16.819 -29.451 1.00 20.08  ? 318 ARG A HG2    1 
ATOM   4960  H HG3    . ARG A 1 318 ? -16.969 -15.861 -30.610 1.00 20.08  ? 318 ARG A HG3    1 
ATOM   4961  H HD2    . ARG A 1 318 ? -18.846 -17.362 -30.820 1.00 21.74  ? 318 ARG A HD2    1 
ATOM   4962  H HD3    . ARG A 1 318 ? -18.384 -17.977 -29.434 1.00 21.74  ? 318 ARG A HD3    1 
ATOM   4963  H HE     . ARG A 1 318 ? -19.724 -15.687 -29.713 1.00 20.37  ? 318 ARG A HE     1 
ATOM   4964  H HH11   . ARG A 1 318 ? -17.759 -17.236 -27.543 1.00 19.36  ? 318 ARG A HH11   1 
ATOM   4965  H HH12   . ARG A 1 318 ? -18.230 -16.488 -26.345 1.00 19.36  ? 318 ARG A HH12   1 
ATOM   4966  H HH21   . ARG A 1 318 ? -20.454 -14.603 -27.857 1.00 17.36  ? 318 ARG A HH21   1 
ATOM   4967  H HH22   . ARG A 1 318 ? -19.847 -14.907 -26.531 1.00 17.36  ? 318 ARG A HH22   1 
ATOM   4968  N N      . VAL A 1 319 ? -17.911 -20.186 -31.690 1.00 16.31  ? 319 VAL A N      1 
ATOM   4969  C CA     . VAL A 1 319 ? -19.171 -20.905 -31.594 1.00 16.75  ? 319 VAL A CA     1 
ATOM   4970  C C      . VAL A 1 319 ? -18.970 -22.357 -31.137 1.00 16.89  ? 319 VAL A C      1 
ATOM   4971  O O      . VAL A 1 319 ? -19.750 -22.878 -30.331 1.00 17.38  ? 319 VAL A O      1 
ATOM   4972  C CB     . VAL A 1 319 ? -19.909 -20.843 -32.946 1.00 17.54  ? 319 VAL A CB     1 
ATOM   4973  C CG1    . VAL A 1 319 ? -21.107 -21.775 -32.972 1.00 20.11  ? 319 VAL A CG1    1 
ATOM   4974  C CG2    . VAL A 1 319 ? -20.354 -19.406 -33.223 1.00 17.47  ? 319 VAL A CG2    1 
ATOM   4975  H H      . VAL A 1 319 ? -17.703 -19.950 -32.490 1.00 19.57  ? 319 VAL A H      1 
ATOM   4976  H HA     . VAL A 1 319 ? -19.729 -20.465 -30.934 1.00 20.10  ? 319 VAL A HA     1 
ATOM   4977  H HB     . VAL A 1 319 ? -19.301 -21.112 -33.653 1.00 21.05  ? 319 VAL A HB     1 
ATOM   4978  H HG11   . VAL A 1 319 ? -21.683 -21.525 -33.711 1.00 24.14  ? 319 VAL A HG11   1 
ATOM   4979  H HG12   . VAL A 1 319 ? -20.799 -22.687 -33.089 1.00 24.14  ? 319 VAL A HG12   1 
ATOM   4980  H HG13   . VAL A 1 319 ? -21.590 -21.691 -32.135 1.00 24.14  ? 319 VAL A HG13   1 
ATOM   4981  H HG21   . VAL A 1 319 ? -20.821 -19.379 -34.073 1.00 20.96  ? 319 VAL A HG21   1 
ATOM   4982  H HG22   . VAL A 1 319 ? -20.945 -19.116 -32.511 1.00 20.96  ? 319 VAL A HG22   1 
ATOM   4983  H HG23   . VAL A 1 319 ? -19.571 -18.834 -33.257 1.00 20.96  ? 319 VAL A HG23   1 
ATOM   4984  N N      . LYS A 1 320 ? -17.920 -23.013 -31.619 1.00 15.71  ? 320 LYS A N      1 
ATOM   4985  C CA     . LYS A 1 320 ? -17.686 -24.410 -31.251 1.00 17.44  ? 320 LYS A CA     1 
ATOM   4986  C C      . LYS A 1 320 ? -17.208 -24.570 -29.804 1.00 19.46  ? 320 LYS A C      1 
ATOM   4987  O O      . LYS A 1 320 ? -17.398 -25.620 -29.197 1.00 16.13  ? 320 LYS A O      1 
ATOM   4988  C CB     . LYS A 1 320 ? -16.689 -25.051 -32.211 1.00 15.97  ? 320 LYS A CB     1 
ATOM   4989  C CG     . LYS A 1 320 ? -17.323 -25.399 -33.555 1.00 20.15  ? 320 LYS A CG     1 
ATOM   4990  C CD     . LYS A 1 320 ? -16.375 -26.116 -34.494 1.00 21.73  ? 320 LYS A CD     1 
ATOM   4991  C CE     . LYS A 1 320 ? -17.120 -26.612 -35.727 1.00 24.41  ? 320 LYS A CE     1 
ATOM   4992  N NZ     . LYS A 1 320 ? -16.197 -27.130 -36.770 1.00 28.90  ? 320 LYS A NZ     1 
ATOM   4993  H H      . LYS A 1 320 ? -17.334 -22.680 -32.154 1.00 18.85  ? 320 LYS A H      1 
ATOM   4994  H HA     . LYS A 1 320 ? -18.522 -24.894 -31.336 1.00 20.93  ? 320 LYS A HA     1 
ATOM   4995  H HB2    . LYS A 1 320 ? -15.959 -24.432 -32.372 1.00 19.16  ? 320 LYS A HB2    1 
ATOM   4996  H HB3    . LYS A 1 320 ? -16.351 -25.870 -31.817 1.00 19.16  ? 320 LYS A HB3    1 
ATOM   4997  H HG2    . LYS A 1 320 ? -18.086 -25.978 -33.402 1.00 24.18  ? 320 LYS A HG2    1 
ATOM   4998  H HG3    . LYS A 1 320 ? -17.611 -24.580 -33.989 1.00 24.18  ? 320 LYS A HG3    1 
ATOM   4999  H HD2    . LYS A 1 320 ? -15.683 -25.501 -34.782 1.00 26.07  ? 320 LYS A HD2    1 
ATOM   5000  H HD3    . LYS A 1 320 ? -15.981 -26.875 -34.044 1.00 26.07  ? 320 LYS A HD3    1 
ATOM   5001  H HE2    . LYS A 1 320 ? -17.718 -27.331 -35.469 1.00 29.29  ? 320 LYS A HE2    1 
ATOM   5002  H HE3    . LYS A 1 320 ? -17.625 -25.879 -36.107 1.00 29.29  ? 320 LYS A HE3    1 
ATOM   5003  H HZ1    . LYS A 1 320 ? -16.662 -27.406 -37.477 1.00 34.68  ? 320 LYS A HZ1    1 
ATOM   5004  H HZ2    . LYS A 1 320 ? -15.636 -26.488 -37.026 1.00 34.68  ? 320 LYS A HZ2    1 
ATOM   5005  H HZ3    . LYS A 1 320 ? -15.727 -27.813 -36.448 1.00 34.68  ? 320 LYS A HZ3    1 
ATOM   5006  N N      . GLN A 1 321 ? -16.595 -23.533 -29.246 1.00 16.41  ? 321 GLN A N      1 
ATOM   5007  C CA     . GLN A 1 321 ? -16.229 -23.560 -27.828 1.00 15.35  ? 321 GLN A CA     1 
ATOM   5008  C C      . GLN A 1 321 ? -17.483 -23.539 -26.947 1.00 16.17  ? 321 GLN A C      1 
ATOM   5009  O O      . GLN A 1 321 ? -17.582 -24.276 -25.963 1.00 17.48  ? 321 GLN A O      1 
ATOM   5010  C CB     . GLN A 1 321 ? -15.311 -22.378 -27.486 1.00 17.01  ? 321 GLN A CB     1 
ATOM   5011  C CG     . GLN A 1 321 ? -14.755 -22.408 -26.078 1.00 21.27  ? 321 GLN A CG     1 
ATOM   5012  C CD     . GLN A 1 321 ? -14.035 -21.120 -25.712 1.00 20.73  ? 321 GLN A CD     1 
ATOM   5013  O OE1    . GLN A 1 321 ? -14.644 -20.047 -25.640 1.00 18.33  ? 321 GLN A OE1    1 
ATOM   5014  N NE2    . GLN A 1 321 ? -12.737 -21.224 -25.465 1.00 19.78  ? 321 GLN A NE2    1 
ATOM   5015  H H      . GLN A 1 321 ? -16.380 -22.809 -29.657 1.00 19.70  ? 321 GLN A H      1 
ATOM   5016  H HA     . GLN A 1 321 ? -15.744 -24.379 -27.641 1.00 18.42  ? 321 GLN A HA     1 
ATOM   5017  H HB2    . GLN A 1 321 ? -14.560 -22.380 -28.100 1.00 20.42  ? 321 GLN A HB2    1 
ATOM   5018  H HB3    . GLN A 1 321 ? -15.814 -21.555 -27.587 1.00 20.42  ? 321 GLN A HB3    1 
ATOM   5019  H HG2    . GLN A 1 321 ? -15.482 -22.532 -25.449 1.00 25.52  ? 321 GLN A HG2    1 
ATOM   5020  H HG3    . GLN A 1 321 ? -14.122 -23.139 -26.003 1.00 25.52  ? 321 GLN A HG3    1 
ATOM   5021  H HE21   . GLN A 1 321 ? -12.349 -21.990 -25.517 1.00 23.73  ? 321 GLN A HE21   1 
ATOM   5022  H HE22   . GLN A 1 321 ? -12.282 -20.525 -25.253 1.00 23.73  ? 321 GLN A HE22   1 
ATOM   5023  N N      . VAL A 1 322 ? -18.452 -22.706 -27.308 1.00 16.13  ? 322 VAL A N      1 
ATOM   5024  C CA     . VAL A 1 322 ? -19.715 -22.666 -26.594 1.00 16.54  ? 322 VAL A CA     1 
ATOM   5025  C C      . VAL A 1 322 ? -20.406 -24.030 -26.729 1.00 19.01  ? 322 VAL A C      1 
ATOM   5026  O O      . VAL A 1 322 ? -20.936 -24.597 -25.766 1.00 16.61  ? 322 VAL A O      1 
ATOM   5027  C CB     . VAL A 1 322 ? -20.623 -21.552 -27.142 1.00 16.73  ? 322 VAL A CB     1 
ATOM   5028  C CG1    . VAL A 1 322 ? -21.976 -21.551 -26.453 1.00 17.89  ? 322 VAL A CG1    1 
ATOM   5029  C CG2    . VAL A 1 322 ? -19.941 -20.177 -26.995 1.00 16.48  ? 322 VAL A CG2    1 
ATOM   5030  H H      . VAL A 1 322 ? -18.400 -22.154 -27.965 1.00 19.35  ? 322 VAL A H      1 
ATOM   5031  H HA     . VAL A 1 322 ? -19.551 -22.495 -25.653 1.00 19.84  ? 322 VAL A HA     1 
ATOM   5032  H HB     . VAL A 1 322 ? -20.773 -21.708 -28.088 1.00 20.07  ? 322 VAL A HB     1 
ATOM   5033  H HG11   . VAL A 1 322 ? -22.438 -20.726 -26.670 1.00 21.46  ? 322 VAL A HG11   1 
ATOM   5034  H HG12   . VAL A 1 322 ? -22.493 -22.310 -26.765 1.00 21.46  ? 322 VAL A HG12   1 
ATOM   5035  H HG13   . VAL A 1 322 ? -21.842 -21.611 -25.494 1.00 21.46  ? 322 VAL A HG13   1 
ATOM   5036  H HG21   . VAL A 1 322 ? -20.546 -19.489 -27.314 1.00 19.77  ? 322 VAL A HG21   1 
ATOM   5037  H HG22   . VAL A 1 322 ? -19.734 -20.027 -26.060 1.00 19.77  ? 322 VAL A HG22   1 
ATOM   5038  H HG23   . VAL A 1 322 ? -19.126 -20.170 -27.520 1.00 19.77  ? 322 VAL A HG23   1 
ATOM   5039  N N      . ARG A 1 323 ? -20.393 -24.548 -27.950 1.00 15.34  ? 323 ARG A N      1 
ATOM   5040  C CA     . ARG A 1 323 ? -21.000 -25.847 -28.246 1.00 17.32  ? 323 ARG A CA     1 
ATOM   5041  C C      . ARG A 1 323 ? -20.371 -26.962 -27.412 1.00 18.55  ? 323 ARG A C      1 
ATOM   5042  O O      . ARG A 1 323 ? -21.071 -27.850 -26.914 1.00 16.73  ? 323 ARG A O      1 
ATOM   5043  C CB     . ARG A 1 323 ? -20.859 -26.154 -29.736 1.00 14.74  ? 323 ARG A CB     1 
ATOM   5044  C CG     . ARG A 1 323 ? -21.528 -27.433 -30.184 1.00 18.35  ? 323 ARG A CG     1 
ATOM   5045  C CD     . ARG A 1 323 ? -21.377 -27.622 -31.689 1.00 20.46  ? 323 ARG A CD     1 
ATOM   5046  N NE     . ARG A 1 323 ? -22.100 -26.592 -32.429 1.00 20.80  ? 323 ARG A NE     1 
ATOM   5047  C CZ     . ARG A 1 323 ? -21.928 -26.329 -33.722 1.00 22.48  ? 323 ARG A CZ     1 
ATOM   5048  N NH1    . ARG A 1 323 ? -21.048 -27.011 -34.439 1.00 24.33  ? 323 ARG A NH1    1 
ATOM   5049  N NH2    . ARG A 1 323 ? -22.639 -25.377 -34.294 1.00 21.85  ? 323 ARG A NH2    1 
ATOM   5050  H H      . ARG A 1 323 ? -20.037 -24.166 -28.633 1.00 18.41  ? 323 ARG A H      1 
ATOM   5051  H HA     . ARG A 1 323 ? -21.946 -25.810 -28.034 1.00 20.78  ? 323 ARG A HA     1 
ATOM   5052  H HB2    . ARG A 1 323 ? -21.252 -25.424 -30.240 1.00 17.68  ? 323 ARG A HB2    1 
ATOM   5053  H HB3    . ARG A 1 323 ? -19.915 -26.226 -29.949 1.00 17.68  ? 323 ARG A HB3    1 
ATOM   5054  H HG2    . ARG A 1 323 ? -21.114 -28.189 -29.739 1.00 22.02  ? 323 ARG A HG2    1 
ATOM   5055  H HG3    . ARG A 1 323 ? -22.474 -27.393 -29.973 1.00 22.02  ? 323 ARG A HG3    1 
ATOM   5056  H HD2    . ARG A 1 323 ? -20.438 -27.565 -31.925 1.00 24.55  ? 323 ARG A HD2    1 
ATOM   5057  H HD3    . ARG A 1 323 ? -21.736 -28.487 -31.941 1.00 24.55  ? 323 ARG A HD3    1 
ATOM   5058  H HE     . ARG A 1 323 ? -22.678 -26.122 -31.999 1.00 24.96  ? 323 ARG A HE     1 
ATOM   5059  H HH11   . ARG A 1 323 ? -20.581 -27.634 -34.074 1.00 29.19  ? 323 ARG A HH11   1 
ATOM   5060  H HH12   . ARG A 1 323 ? -20.944 -26.832 -35.274 1.00 29.19  ? 323 ARG A HH12   1 
ATOM   5061  H HH21   . ARG A 1 323 ? -23.210 -24.930 -33.832 1.00 26.23  ? 323 ARG A HH21   1 
ATOM   5062  H HH22   . ARG A 1 323 ? -22.530 -25.201 -35.129 1.00 26.23  ? 323 ARG A HH22   1 
ATOM   5063  N N      . TYR A 1 324 ? -19.053 -26.902 -27.258 1.00 16.53  ? 324 TYR A N      1 
ATOM   5064  C CA     . TYR A 1 324 ? -18.309 -27.889 -26.476 1.00 15.05  ? 324 TYR A CA     1 
ATOM   5065  C C      . TYR A 1 324 ? -18.854 -27.958 -25.065 1.00 17.79  ? 324 TYR A C      1 
ATOM   5066  O O      . TYR A 1 324 ? -19.091 -29.048 -24.528 1.00 16.81  ? 324 TYR A O      1 
ATOM   5067  C CB     . TYR A 1 324 ? -16.816 -27.543 -26.448 1.00 15.95  ? 324 TYR A CB     1 
ATOM   5068  C CG     . TYR A 1 324 ? -15.984 -28.459 -25.573 1.00 17.12  ? 324 TYR A CG     1 
ATOM   5069  C CD1    . TYR A 1 324 ? -15.467 -29.648 -26.075 1.00 22.24  ? 324 TYR A CD1    1 
ATOM   5070  C CD2    . TYR A 1 324 ? -15.713 -28.137 -24.248 1.00 18.97  ? 324 TYR A CD2    1 
ATOM   5071  C CE1    . TYR A 1 324 ? -14.705 -30.490 -25.283 1.00 25.51  ? 324 TYR A CE1    1 
ATOM   5072  C CE2    . TYR A 1 324 ? -14.944 -28.976 -23.448 1.00 21.40  ? 324 TYR A CE2    1 
ATOM   5073  C CZ     . TYR A 1 324 ? -14.447 -30.151 -23.972 1.00 25.31  ? 324 TYR A CZ     1 
ATOM   5074  O OH     . TYR A 1 324 ? -13.692 -31.001 -23.191 1.00 27.20  ? 324 TYR A OH     1 
ATOM   5075  H H      . TYR A 1 324 ? -18.557 -26.289 -27.602 1.00 19.84  ? 324 TYR A H      1 
ATOM   5076  H HA     . TYR A 1 324 ? -18.411 -28.763 -26.884 1.00 18.06  ? 324 TYR A HA     1 
ATOM   5077  H HB2    . TYR A 1 324 ? -16.466 -27.599 -27.351 1.00 19.14  ? 324 TYR A HB2    1 
ATOM   5078  H HB3    . TYR A 1 324 ? -16.711 -26.640 -26.111 1.00 19.14  ? 324 TYR A HB3    1 
ATOM   5079  H HD1    . TYR A 1 324 ? -15.637 -29.883 -26.959 1.00 26.68  ? 324 TYR A HD1    1 
ATOM   5080  H HD2    . TYR A 1 324 ? -16.047 -27.345 -23.892 1.00 22.77  ? 324 TYR A HD2    1 
ATOM   5081  H HE1    . TYR A 1 324 ? -14.369 -31.283 -25.634 1.00 30.62  ? 324 TYR A HE1    1 
ATOM   5082  H HE2    . TYR A 1 324 ? -14.773 -28.750 -22.562 1.00 25.68  ? 324 TYR A HE2    1 
ATOM   5083  H HH     . TYR A 1 324 ? -13.464 -30.612 -22.485 1.00 32.64  ? 324 TYR A HH     1 
ATOM   5084  N N      . LEU A 1 325 ? -19.050 -26.790 -24.462 1.00 15.70  ? 325 LEU A N      1 
ATOM   5085  C CA     . LEU A 1 325 ? -19.607 -26.725 -23.117 1.00 16.44  ? 325 LEU A CA     1 
ATOM   5086  C C      . LEU A 1 325 ? -20.993 -27.355 -23.084 1.00 19.67  ? 325 LEU A C      1 
ATOM   5087  O O      . LEU A 1 325 ? -21.293 -28.181 -22.211 1.00 19.14  ? 325 LEU A O      1 
ATOM   5088  C CB     . LEU A 1 325 ? -19.681 -25.281 -22.629 1.00 16.49  ? 325 LEU A CB     1 
ATOM   5089  C CG     . LEU A 1 325 ? -20.329 -25.053 -21.266 1.00 15.49  ? 325 LEU A CG     1 
ATOM   5090  C CD1    . LEU A 1 325 ? -19.676 -25.891 -20.172 1.00 19.04  ? 325 LEU A CD1    1 
ATOM   5091  C CD2    . LEU A 1 325 ? -20.285 -23.571 -20.905 1.00 18.74  ? 325 LEU A CD2    1 
ATOM   5092  H H      . LEU A 1 325 ? -18.869 -26.024 -24.809 1.00 18.84  ? 325 LEU A H      1 
ATOM   5093  H HA     . LEU A 1 325 ? -19.034 -27.221 -22.512 1.00 19.73  ? 325 LEU A HA     1 
ATOM   5094  H HB2    . LEU A 1 325 ? -18.778 -24.931 -22.579 1.00 19.79  ? 325 LEU A HB2    1 
ATOM   5095  H HB3    . LEU A 1 325 ? -20.188 -24.768 -23.277 1.00 19.79  ? 325 LEU A HB3    1 
ATOM   5096  H HG     . LEU A 1 325 ? -21.262 -25.313 -21.317 1.00 18.59  ? 325 LEU A HG     1 
ATOM   5097  H HD11   . LEU A 1 325 ? -20.063 -25.648 -19.316 1.00 22.85  ? 325 LEU A HD11   1 
ATOM   5098  H HD12   . LEU A 1 325 ? -19.838 -26.830 -20.353 1.00 22.85  ? 325 LEU A HD12   1 
ATOM   5099  H HD13   . LEU A 1 325 ? -18.722 -25.714 -20.166 1.00 22.85  ? 325 LEU A HD13   1 
ATOM   5100  H HD21   . LEU A 1 325 ? -20.701 -23.445 -20.038 1.00 22.49  ? 325 LEU A HD21   1 
ATOM   5101  H HD22   . LEU A 1 325 ? -19.360 -23.281 -20.874 1.00 22.49  ? 325 LEU A HD22   1 
ATOM   5102  H HD23   . LEU A 1 325 ? -20.767 -23.068 -21.580 1.00 22.49  ? 325 LEU A HD23   1 
ATOM   5103  N N      . GLY A 1 326 ? -21.840 -26.957 -24.032 1.00 16.67  ? 326 GLY A N      1 
ATOM   5104  C CA     . GLY A 1 326 ? -23.205 -27.449 -24.080 1.00 20.71  ? 326 GLY A CA     1 
ATOM   5105  C C      . GLY A 1 326 ? -23.270 -28.957 -24.273 1.00 22.80  ? 326 GLY A C      1 
ATOM   5106  O O      . GLY A 1 326 ? -24.053 -29.646 -23.616 1.00 21.53  ? 326 GLY A O      1 
ATOM   5107  H H      . GLY A 1 326 ? -21.644 -26.401 -24.658 1.00 20.00  ? 326 GLY A H      1 
ATOM   5108  H HA2    . GLY A 1 326 ? -23.659 -27.225 -23.252 1.00 24.86  ? 326 GLY A HA2    1 
ATOM   5109  H HA3    . GLY A 1 326 ? -23.676 -27.024 -24.814 1.00 24.86  ? 326 GLY A HA3    1 
ATOM   5110  N N      . GLU A 1 327 ? -22.438 -29.474 -25.169 1.00 21.20  ? 327 GLU A N      1 
ATOM   5111  C CA     . GLU A 1 327 ? -22.454 -30.893 -25.493 1.00 22.59  ? 327 GLU A CA     1 
ATOM   5112  C C      . GLU A 1 327 ? -21.888 -31.733 -24.356 1.00 23.06  ? 327 GLU A C      1 
ATOM   5113  O O      . GLU A 1 327 ? -22.342 -32.855 -24.123 1.00 22.50  ? 327 GLU A O      1 
ATOM   5114  C CB     . GLU A 1 327 ? -21.676 -31.145 -26.785 1.00 27.65  ? 327 GLU A CB     1 
ATOM   5115  C CG     . GLU A 1 327 ? -22.386 -30.625 -28.017 1.00 30.87  ? 327 GLU A CG     1 
ATOM   5116  C CD     . GLU A 1 327 ? -23.677 -31.366 -28.310 1.00 39.11  ? 327 GLU A CD     1 
ATOM   5117  O OE1    . GLU A 1 327 ? -23.789 -32.545 -27.907 1.00 41.00  ? 327 GLU A OE1    1 
ATOM   5118  O OE2    . GLU A 1 327 ? -24.580 -30.769 -28.936 1.00 54.74  ? 327 GLU A OE2    1 
ATOM   5119  H H      . GLU A 1 327 ? -21.852 -29.021 -25.605 1.00 25.45  ? 327 GLU A H      1 
ATOM   5120  H HA     . GLU A 1 327 ? -23.372 -31.171 -25.636 1.00 27.10  ? 327 GLU A HA     1 
ATOM   5121  H HB2    . GLU A 1 327 ? -20.818 -30.696 -26.726 1.00 33.18  ? 327 GLU A HB2    1 
ATOM   5122  H HB3    . GLU A 1 327 ? -21.541 -32.099 -26.893 1.00 33.18  ? 327 GLU A HB3    1 
ATOM   5123  H HG2    . GLU A 1 327 ? -22.602 -29.689 -27.886 1.00 37.05  ? 327 GLU A HG2    1 
ATOM   5124  H HG3    . GLU A 1 327 ? -21.802 -30.726 -28.785 1.00 37.05  ? 327 GLU A HG3    1 
ATOM   5125  N N      . LYS A 1 328 ? -20.914 -31.192 -23.630 1.00 17.63  ? 328 LYS A N      1 
ATOM   5126  C CA     . LYS A 1 328 ? -20.343 -31.905 -22.499 1.00 22.17  ? 328 LYS A CA     1 
ATOM   5127  C C      . LYS A 1 328 ? -21.394 -32.050 -21.396 1.00 20.72  ? 328 LYS A C      1 
ATOM   5128  O O      . LYS A 1 328 ? -21.518 -33.095 -20.759 1.00 19.46  ? 328 LYS A O      1 
ATOM   5129  C CB     . LYS A 1 328 ? -19.108 -31.180 -21.976 1.00 23.68  ? 328 LYS A CB     1 
ATOM   5130  C CG     . LYS A 1 328 ? -18.346 -31.959 -20.944 1.00 31.42  ? 328 LYS A CG     1 
ATOM   5131  C CD     . LYS A 1 328 ? -16.867 -31.632 -21.002 1.00 33.93  ? 328 LYS A CD     1 
ATOM   5132  C CE     . LYS A 1 328 ? -16.059 -32.544 -20.095 1.00 35.29  ? 328 LYS A CE     1 
ATOM   5133  N NZ     . LYS A 1 328 ? -15.973 -32.003 -18.724 1.00 37.85  ? 328 LYS A NZ     1 
ATOM   5134  H H      . LYS A 1 328 ? -20.569 -30.417 -23.773 1.00 21.15  ? 328 LYS A H      1 
ATOM   5135  H HA     . LYS A 1 328 ? -20.076 -32.793 -22.783 1.00 26.60  ? 328 LYS A HA     1 
ATOM   5136  H HB2    . LYS A 1 328 ? -18.511 -31.004 -22.720 1.00 28.41  ? 328 LYS A HB2    1 
ATOM   5137  H HB3    . LYS A 1 328 ? -19.385 -30.343 -21.571 1.00 28.41  ? 328 LYS A HB3    1 
ATOM   5138  H HG2    . LYS A 1 328 ? -18.675 -31.731 -20.061 1.00 37.70  ? 328 LYS A HG2    1 
ATOM   5139  H HG3    . LYS A 1 328 ? -18.457 -32.908 -21.111 1.00 37.70  ? 328 LYS A HG3    1 
ATOM   5140  H HD2    . LYS A 1 328 ? -16.547 -31.749 -21.910 1.00 40.72  ? 328 LYS A HD2    1 
ATOM   5141  H HD3    . LYS A 1 328 ? -16.730 -30.716 -20.713 1.00 40.72  ? 328 LYS A HD3    1 
ATOM   5142  H HE2    . LYS A 1 328 ? -16.485 -33.414 -20.052 1.00 42.35  ? 328 LYS A HE2    1 
ATOM   5143  H HE3    . LYS A 1 328 ? -15.158 -32.628 -20.446 1.00 42.35  ? 328 LYS A HE3    1 
ATOM   5144  H HZ1    . LYS A 1 328 ? -15.496 -32.552 -18.210 1.00 45.41  ? 328 LYS A HZ1    1 
ATOM   5145  H HZ2    . LYS A 1 328 ? -15.581 -31.204 -18.736 1.00 45.41  ? 328 LYS A HZ2    1 
ATOM   5146  H HZ3    . LYS A 1 328 ? -16.789 -31.919 -18.379 1.00 45.41  ? 328 LYS A HZ3    1 
ATOM   5147  N N      . LEU A 1 329 ? -22.158 -30.989 -21.179 1.00 16.76  ? 329 LEU A N      1 
ATOM   5148  C CA     . LEU A 1 329 ? -23.250 -31.032 -20.221 1.00 20.54  ? 329 LEU A CA     1 
ATOM   5149  C C      . LEU A 1 329 ? -24.323 -32.029 -20.675 1.00 22.61  ? 329 LEU A C      1 
ATOM   5150  O O      . LEU A 1 329 ? -24.791 -32.857 -19.890 1.00 19.19  ? 329 LEU A O      1 
ATOM   5151  C CB     . LEU A 1 329 ? -23.841 -29.634 -20.044 1.00 22.51  ? 329 LEU A CB     1 
ATOM   5152  C CG     . LEU A 1 329 ? -22.932 -28.642 -19.306 1.00 18.52  ? 329 LEU A CG     1 
ATOM   5153  C CD1    . LEU A 1 329 ? -23.485 -27.233 -19.406 1.00 19.31  ? 329 LEU A CD1    1 
ATOM   5154  C CD2    . LEU A 1 329 ? -22.756 -29.018 -17.841 1.00 21.04  ? 329 LEU A CD2    1 
ATOM   5155  H H      . LEU A 1 329 ? -22.064 -30.231 -21.574 1.00 20.11  ? 329 LEU A H      1 
ATOM   5156  H HA     . LEU A 1 329 ? -22.909 -31.329 -19.363 1.00 24.65  ? 329 LEU A HA     1 
ATOM   5157  H HB2    . LEU A 1 329 ? -24.028 -29.264 -20.921 1.00 27.01  ? 329 LEU A HB2    1 
ATOM   5158  H HB3    . LEU A 1 329 ? -24.666 -29.708 -19.539 1.00 27.01  ? 329 LEU A HB3    1 
ATOM   5159  H HG     . LEU A 1 329 ? -22.056 -28.649 -19.723 1.00 22.23  ? 329 LEU A HG     1 
ATOM   5160  H HD11   . LEU A 1 329 ? -22.893 -26.627 -18.933 1.00 23.18  ? 329 LEU A HD11   1 
ATOM   5161  H HD12   . LEU A 1 329 ? -23.538 -26.981 -20.341 1.00 23.18  ? 329 LEU A HD12   1 
ATOM   5162  H HD13   . LEU A 1 329 ? -24.369 -27.212 -19.007 1.00 23.18  ? 329 LEU A HD13   1 
ATOM   5163  H HD21   . LEU A 1 329 ? -22.269 -28.310 -17.390 1.00 25.25  ? 329 LEU A HD21   1 
ATOM   5164  H HD22   . LEU A 1 329 ? -23.631 -29.127 -17.437 1.00 25.25  ? 329 LEU A HD22   1 
ATOM   5165  H HD23   . LEU A 1 329 ? -22.259 -29.849 -17.785 1.00 25.25  ? 329 LEU A HD23   1 
ATOM   5166  N N      . LYS A 1 330 ? -24.700 -31.954 -21.946 1.00 21.61  ? 330 LYS A N      1 
ATOM   5167  C CA     . LYS A 1 330 ? -25.709 -32.862 -22.491 1.00 27.31  ? 330 LYS A CA     1 
ATOM   5168  C C      . LYS A 1 330 ? -25.288 -34.315 -22.350 1.00 24.46  ? 330 LYS A C      1 
ATOM   5169  O O      . LYS A 1 330 ? -26.115 -35.172 -22.051 1.00 25.95  ? 330 LYS A O      1 
ATOM   5170  C CB     . LYS A 1 330 ? -25.985 -32.555 -23.966 1.00 27.23  ? 330 LYS A CB     1 
ATOM   5171  C CG     . LYS A 1 330 ? -26.920 -31.391 -24.216 1.00 32.21  ? 330 LYS A CG     1 
ATOM   5172  C CD     . LYS A 1 330 ? -27.625 -31.513 -25.570 1.00 39.80  ? 330 LYS A CD     1 
ATOM   5173  C CE     . LYS A 1 330 ? -26.655 -31.805 -26.699 1.00 50.00  ? 330 LYS A CE     1 
ATOM   5174  N NZ     . LYS A 1 330 ? -27.302 -31.727 -28.040 1.00 60.61  ? 330 LYS A NZ     1 
ATOM   5175  H H      . LYS A 1 330 ? -24.389 -31.389 -22.515 1.00 25.93  ? 330 LYS A H      1 
ATOM   5176  H HA     . LYS A 1 330 ? -26.537 -32.743 -22.000 1.00 32.78  ? 330 LYS A HA     1 
ATOM   5177  H HB2    . LYS A 1 330 ? -25.142 -32.352 -24.401 1.00 32.67  ? 330 LYS A HB2    1 
ATOM   5178  H HB3    . LYS A 1 330 ? -26.381 -33.341 -24.374 1.00 32.67  ? 330 LYS A HB3    1 
ATOM   5179  H HG2    . LYS A 1 330 ? -27.598 -31.370 -23.522 1.00 38.65  ? 330 LYS A HG2    1 
ATOM   5180  H HG3    . LYS A 1 330 ? -26.411 -30.565 -24.213 1.00 38.65  ? 330 LYS A HG3    1 
ATOM   5181  H HD2    . LYS A 1 330 ? -28.268 -32.239 -25.529 1.00 47.75  ? 330 LYS A HD2    1 
ATOM   5182  H HD3    . LYS A 1 330 ? -28.077 -30.678 -25.769 1.00 47.75  ? 330 LYS A HD3    1 
ATOM   5183  H HE2    . LYS A 1 330 ? -25.934 -31.157 -26.673 1.00 60.01  ? 330 LYS A HE2    1 
ATOM   5184  H HE3    . LYS A 1 330 ? -26.301 -32.702 -26.595 1.00 60.01  ? 330 LYS A HE3    1 
ATOM   5185  H HZ1    . LYS A 1 330 ? -26.705 -31.903 -28.676 1.00 72.74  ? 330 LYS A HZ1    1 
ATOM   5186  H HZ2    . LYS A 1 330 ? -27.965 -32.319 -28.093 1.00 72.74  ? 330 LYS A HZ2    1 
ATOM   5187  H HZ3    . LYS A 1 330 ? -27.632 -30.911 -28.171 1.00 72.74  ? 330 LYS A HZ3    1 
ATOM   5188  N N      . ALA A 1 331 ? -24.002 -34.592 -22.560 1.00 25.30  ? 331 ALA A N      1 
ATOM   5189  C CA     . ALA A 1 331 ? -23.491 -35.960 -22.515 1.00 27.40  ? 331 ALA A CA     1 
ATOM   5190  C C      . ALA A 1 331 ? -23.569 -36.558 -21.112 1.00 28.49  ? 331 ALA A C      1 
ATOM   5191  O O      . ALA A 1 331 ? -23.534 -37.776 -20.958 1.00 25.65  ? 331 ALA A O      1 
ATOM   5192  C CB     . ALA A 1 331 ? -22.051 -36.010 -23.017 1.00 29.04  ? 331 ALA A CB     1 
ATOM   5193  H H      . ALA A 1 331 ? -23.402 -34.001 -22.732 1.00 30.37  ? 331 ALA A H      1 
ATOM   5194  H HA     . ALA A 1 331 ? -24.029 -36.513 -23.103 1.00 32.87  ? 331 ALA A HA     1 
ATOM   5195  H HB1    . ALA A 1 331 ? -21.735 -36.926 -22.978 1.00 34.85  ? 331 ALA A HB1    1 
ATOM   5196  H HB2    . ALA A 1 331 ? -22.025 -35.690 -23.932 1.00 34.85  ? 331 ALA A HB2    1 
ATOM   5197  H HB3    . ALA A 1 331 ? -21.500 -35.445 -22.452 1.00 34.85  ? 331 ALA A HB3    1 
ATOM   5198  N N      . ALA A 1 332 ? -23.661 -35.697 -20.101 1.00 24.28  ? 332 ALA A N      1 
ATOM   5199  C CA     . ALA A 1 332 ? -23.775 -36.136 -18.712 1.00 26.76  ? 332 ALA A CA     1 
ATOM   5200  C C      . ALA A 1 332 ? -25.228 -36.077 -18.230 1.00 23.33  ? 332 ALA A C      1 
ATOM   5201  O O      . ALA A 1 332 ? -25.515 -36.343 -17.062 1.00 28.58  ? 332 ALA A O      1 
ATOM   5202  C CB     . ALA A 1 332 ? -22.888 -35.279 -17.818 1.00 28.91  ? 332 ALA A CB     1 
ATOM   5203  H H      . ALA A 1 332 ? -23.659 -34.842 -20.193 1.00 29.14  ? 332 ALA A H      1 
ATOM   5204  H HA     . ALA A 1 332 ? -23.472 -37.054 -18.635 1.00 32.12  ? 332 ALA A HA     1 
ATOM   5205  H HB1    . ALA A 1 332 ? -22.974 -35.585 -16.902 1.00 34.70  ? 332 ALA A HB1    1 
ATOM   5206  H HB2    . ALA A 1 332 ? -21.967 -35.366 -18.111 1.00 34.70  ? 332 ALA A HB2    1 
ATOM   5207  H HB3    . ALA A 1 332 ? -23.172 -34.354 -17.886 1.00 34.70  ? 332 ALA A HB3    1 
ATOM   5208  N N      . GLY A 1 333 ? -26.136 -35.705 -19.128 1.00 23.84  ? 333 GLY A N      1 
ATOM   5209  C CA     . GLY A 1 333 ? -27.555 -35.667 -18.822 1.00 25.84  ? 333 GLY A CA     1 
ATOM   5210  C C      . GLY A 1 333 ? -28.052 -34.374 -18.201 1.00 26.38  ? 333 GLY A C      1 
ATOM   5211  O O      . GLY A 1 333 ? -29.208 -34.288 -17.802 1.00 22.25  ? 333 GLY A O      1 
ATOM   5212  H H      . GLY A 1 333 ? -25.953 -35.466 -19.933 1.00 28.61  ? 333 GLY A H      1 
ATOM   5213  H HA2    . GLY A 1 333 ? -28.054 -35.812 -19.641 1.00 31.01  ? 333 GLY A HA2    1 
ATOM   5214  H HA3    . GLY A 1 333 ? -27.767 -36.391 -18.213 1.00 31.01  ? 333 GLY A HA3    1 
ATOM   5215  N N      . VAL A 1 334 ? -27.197 -33.358 -18.130 1.00 22.67  ? 334 VAL A N      1 
ATOM   5216  C CA     . VAL A 1 334 ? -27.609 -32.083 -17.551 1.00 21.64  ? 334 VAL A CA     1 
ATOM   5217  C C      . VAL A 1 334 ? -28.621 -31.392 -18.470 1.00 21.94  ? 334 VAL A C      1 
ATOM   5218  O O      . VAL A 1 334 ? -28.376 -31.265 -19.666 1.00 23.73  ? 334 VAL A O      1 
ATOM   5219  C CB     . VAL A 1 334 ? -26.402 -31.154 -17.318 1.00 19.55  ? 334 VAL A CB     1 
ATOM   5220  C CG1    . VAL A 1 334 ? -26.869 -29.799 -16.778 1.00 21.82  ? 334 VAL A CG1    1 
ATOM   5221  C CG2    . VAL A 1 334 ? -25.406 -31.804 -16.369 1.00 18.99  ? 334 VAL A CG2    1 
ATOM   5222  H H      . VAL A 1 334 ? -26.383 -33.379 -18.406 1.00 27.20  ? 334 VAL A H      1 
ATOM   5223  H HA     . VAL A 1 334 ? -28.016 -32.257 -16.690 1.00 25.97  ? 334 VAL A HA     1 
ATOM   5224  H HB     . VAL A 1 334 ? -25.954 -31.001 -18.164 1.00 23.46  ? 334 VAL A HB     1 
ATOM   5225  H HG11   . VAL A 1 334 ? -26.097 -29.310 -16.452 1.00 26.18  ? 334 VAL A HG11   1 
ATOM   5226  H HG12   . VAL A 1 334 ? -27.297 -29.299 -17.491 1.00 26.18  ? 334 VAL A HG12   1 
ATOM   5227  H HG13   . VAL A 1 334 ? -27.494 -29.947 -16.052 1.00 26.18  ? 334 VAL A HG13   1 
ATOM   5228  H HG21   . VAL A 1 334 ? -24.676 -31.186 -16.207 1.00 22.79  ? 334 VAL A HG21   1 
ATOM   5229  H HG22   . VAL A 1 334 ? -25.855 -32.012 -15.535 1.00 22.79  ? 334 VAL A HG22   1 
ATOM   5230  H HG23   . VAL A 1 334 ? -25.068 -32.618 -16.774 1.00 22.79  ? 334 VAL A HG23   1 
ATOM   5231  N N      . PRO A 1 335 ? -29.762 -30.929 -17.919 1.00 20.12  ? 335 PRO A N      1 
ATOM   5232  C CA     . PRO A 1 335 ? -30.784 -30.282 -18.757 1.00 24.89  ? 335 PRO A CA     1 
ATOM   5233  C C      . PRO A 1 335 ? -30.455 -28.838 -19.153 1.00 27.54  ? 335 PRO A C      1 
ATOM   5234  O O      . PRO A 1 335 ? -30.222 -27.998 -18.283 1.00 27.94  ? 335 PRO A O      1 
ATOM   5235  C CB     . PRO A 1 335 ? -32.034 -30.318 -17.870 1.00 26.19  ? 335 PRO A CB     1 
ATOM   5236  C CG     . PRO A 1 335 ? -31.500 -30.301 -16.479 1.00 23.14  ? 335 PRO A CG     1 
ATOM   5237  C CD     . PRO A 1 335 ? -30.231 -31.110 -16.531 1.00 24.66  ? 335 PRO A CD     1 
ATOM   5238  H HA     . PRO A 1 335 ? -30.945 -30.806 -19.557 1.00 29.87  ? 335 PRO A HA     1 
ATOM   5239  H HB2    . PRO A 1 335 ? -32.581 -29.535 -18.040 1.00 31.43  ? 335 PRO A HB2    1 
ATOM   5240  H HB3    . PRO A 1 335 ? -32.533 -31.132 -18.038 1.00 31.43  ? 335 PRO A HB3    1 
ATOM   5241  H HG2    . PRO A 1 335 ? -31.313 -29.387 -16.212 1.00 27.77  ? 335 PRO A HG2    1 
ATOM   5242  H HG3    . PRO A 1 335 ? -32.142 -30.709 -15.878 1.00 27.77  ? 335 PRO A HG3    1 
ATOM   5243  H HD2    . PRO A 1 335 ? -29.581 -30.757 -15.904 1.00 29.60  ? 335 PRO A HD2    1 
ATOM   5244  H HD3    . PRO A 1 335 ? -30.420 -32.046 -16.358 1.00 29.60  ? 335 PRO A HD3    1 
ATOM   5245  N N      . ILE A 1 336 ? -30.458 -28.565 -20.454 1.00 23.94  ? 336 ILE A N      1 
ATOM   5246  C CA     . ILE A 1 336 ? -30.170 -27.231 -20.976 1.00 24.48  ? 336 ILE A CA     1 
ATOM   5247  C C      . ILE A 1 336 ? -31.165 -26.829 -22.056 1.00 26.17  ? 336 ILE A C      1 
ATOM   5248  O O      . ILE A 1 336 ? -31.806 -27.685 -22.665 1.00 28.39  ? 336 ILE A O      1 
ATOM   5249  C CB     . ILE A 1 336 ? -28.736 -27.147 -21.574 1.00 23.34  ? 336 ILE A CB     1 
ATOM   5250  C CG1    . ILE A 1 336 ? -28.617 -27.975 -22.863 1.00 27.26  ? 336 ILE A CG1    1 
ATOM   5251  C CG2    . ILE A 1 336 ? -27.710 -27.615 -20.560 1.00 21.59  ? 336 ILE A CG2    1 
ATOM   5252  C CD1    . ILE A 1 336 ? -27.316 -27.732 -23.632 1.00 29.57  ? 336 ILE A CD1    1 
ATOM   5253  H H      . ILE A 1 336 ? -30.627 -29.145 -21.066 1.00 28.72  ? 336 ILE A H      1 
ATOM   5254  H HA     . ILE A 1 336 ? -30.236 -26.585 -20.257 1.00 29.37  ? 336 ILE A HA     1 
ATOM   5255  H HB     . ILE A 1 336 ? -28.550 -26.220 -21.790 1.00 28.01  ? 336 ILE A HB     1 
ATOM   5256  H HG12   . ILE A 1 336 ? -28.653 -28.917 -22.633 1.00 32.71  ? 336 ILE A HG12   1 
ATOM   5257  H HG13   . ILE A 1 336 ? -29.340 -27.759 -23.469 1.00 32.71  ? 336 ILE A HG13   1 
ATOM   5258  H HG21   . ILE A 1 336 ? -26.821 -27.422 -20.896 1.00 25.91  ? 336 ILE A HG21   1 
ATOM   5259  H HG22   . ILE A 1 336 ? -27.857 -27.144 -19.725 1.00 25.91  ? 336 ILE A HG22   1 
ATOM   5260  H HG23   . ILE A 1 336 ? -27.813 -28.570 -20.424 1.00 25.91  ? 336 ILE A HG23   1 
ATOM   5261  H HD11   . ILE A 1 336 ? -27.347 -28.225 -24.467 1.00 35.48  ? 336 ILE A HD11   1 
ATOM   5262  H HD12   . ILE A 1 336 ? -27.229 -26.783 -23.811 1.00 35.48  ? 336 ILE A HD12   1 
ATOM   5263  H HD13   . ILE A 1 336 ? -26.569 -28.037 -23.094 1.00 35.48  ? 336 ILE A HD13   1 
ATOM   5264  N N      . VAL A 1 337 ? -31.269 -25.530 -22.317 1.00 23.77  ? 337 VAL A N      1 
ATOM   5265  C CA     . VAL A 1 337 ? -32.042 -25.041 -23.449 1.00 26.39  ? 337 VAL A CA     1 
ATOM   5266  C C      . VAL A 1 337 ? -31.398 -25.542 -24.738 1.00 26.65  ? 337 VAL A C      1 
ATOM   5267  O O      . VAL A 1 337 ? -30.172 -25.548 -24.866 1.00 25.01  ? 337 VAL A O      1 
ATOM   5268  C CB     . VAL A 1 337 ? -32.120 -23.510 -23.455 1.00 21.16  ? 337 VAL A CB     1 
ATOM   5269  C CG1    . VAL A 1 337 ? -32.762 -22.982 -24.745 1.00 33.23  ? 337 VAL A CG1    1 
ATOM   5270  C CG2    . VAL A 1 337 ? -32.893 -23.027 -22.246 1.00 30.69  ? 337 VAL A CG2    1 
ATOM   5271  H H      . VAL A 1 337 ? -30.899 -24.910 -21.850 1.00 28.52  ? 337 VAL A H      1 
ATOM   5272  H HA     . VAL A 1 337 ? -32.944 -25.393 -23.400 1.00 31.67  ? 337 VAL A HA     1 
ATOM   5273  H HB     . VAL A 1 337 ? -31.221 -23.150 -23.400 1.00 25.39  ? 337 VAL A HB     1 
ATOM   5274  H HG11   . VAL A 1 337 ? -33.016 -22.055 -24.613 1.00 39.88  ? 337 VAL A HG11   1 
ATOM   5275  H HG12   . VAL A 1 337 ? -32.121 -23.047 -25.470 1.00 39.88  ? 337 VAL A HG12   1 
ATOM   5276  H HG13   . VAL A 1 337 ? -33.548 -23.513 -24.946 1.00 39.88  ? 337 VAL A HG13   1 
ATOM   5277  H HG21   . VAL A 1 337 ? -32.942 -22.059 -22.269 1.00 36.83  ? 337 VAL A HG21   1 
ATOM   5278  H HG22   . VAL A 1 337 ? -33.786 -23.405 -22.271 1.00 36.83  ? 337 VAL A HG22   1 
ATOM   5279  H HG23   . VAL A 1 337 ? -32.434 -23.316 -21.442 1.00 36.83  ? 337 VAL A HG23   1 
ATOM   5280  N N      . GLU A 1 338 ? -32.225 -25.972 -25.687 1.00 27.86  ? 338 GLU A N      1 
ATOM   5281  C CA     . GLU A 1 338 ? -31.707 -26.498 -26.946 1.00 28.25  ? 338 GLU A CA     1 
ATOM   5282  C C      . GLU A 1 338 ? -32.346 -25.818 -28.150 1.00 28.27  ? 338 GLU A C      1 
ATOM   5283  O O      . GLU A 1 338 ? -33.439 -25.268 -28.049 1.00 32.48  ? 338 GLU A O      1 
ATOM   5284  C CB     . GLU A 1 338 ? -31.915 -28.013 -27.013 1.00 34.47  ? 338 GLU A CB     1 
ATOM   5285  C CG     . GLU A 1 338 ? -31.030 -28.763 -26.019 1.00 35.60  ? 338 GLU A CG     1 
ATOM   5286  C CD     . GLU A 1 338 ? -31.003 -30.257 -26.235 1.00 47.02  ? 338 GLU A CD     1 
ATOM   5287  O OE1    . GLU A 1 338 ? -30.953 -30.694 -27.406 1.00 51.05  ? 338 GLU A OE1    1 
ATOM   5288  O OE2    . GLU A 1 338 ? -31.022 -30.997 -25.226 1.00 49.04  ? 338 GLU A OE2    1 
ATOM   5289  H H      . GLU A 1 338 ? -33.083 -25.970 -25.628 1.00 33.43  ? 338 GLU A H      1 
ATOM   5290  H HA     . GLU A 1 338 ? -30.755 -26.341 -26.968 1.00 33.90  ? 338 GLU A HA     1 
ATOM   5291  H HB2    . GLU A 1 338 ? -32.840 -28.216 -26.805 1.00 41.37  ? 338 GLU A HB2    1 
ATOM   5292  H HB3    . GLU A 1 338 ? -31.699 -28.323 -27.906 1.00 41.37  ? 338 GLU A HB3    1 
ATOM   5293  H HG2    . GLU A 1 338 ? -30.121 -28.435 -26.100 1.00 42.72  ? 338 GLU A HG2    1 
ATOM   5294  H HG3    . GLU A 1 338 ? -31.359 -28.599 -25.122 1.00 42.72  ? 338 GLU A HG3    1 
ATOM   5295  N N      . PRO A 1 339 ? -31.634 -25.795 -29.285 1.00 26.51  ? 339 PRO A N      1 
ATOM   5296  C CA     . PRO A 1 339 ? -30.233 -26.210 -29.391 1.00 26.14  ? 339 PRO A CA     1 
ATOM   5297  C C      . PRO A 1 339 ? -29.317 -25.157 -28.763 1.00 26.46  ? 339 PRO A C      1 
ATOM   5298  O O      . PRO A 1 339 ? -29.780 -24.063 -28.425 1.00 22.42  ? 339 PRO A O      1 
ATOM   5299  C CB     . PRO A 1 339 ? -30.002 -26.328 -30.895 1.00 30.22  ? 339 PRO A CB     1 
ATOM   5300  C CG     . PRO A 1 339 ? -31.123 -25.561 -31.552 1.00 29.82  ? 339 PRO A CG     1 
ATOM   5301  C CD     . PRO A 1 339 ? -32.113 -25.143 -30.514 1.00 27.16  ? 339 PRO A CD     1 
ATOM   5302  H HA     . PRO A 1 339 ? -30.086 -27.073 -28.973 1.00 31.37  ? 339 PRO A HA     1 
ATOM   5303  H HB2    . PRO A 1 339 ? -29.144 -25.938 -31.123 1.00 36.26  ? 339 PRO A HB2    1 
ATOM   5304  H HB3    . PRO A 1 339 ? -30.031 -27.262 -31.155 1.00 36.26  ? 339 PRO A HB3    1 
ATOM   5305  H HG2    . PRO A 1 339 ? -30.753 -24.778 -31.990 1.00 35.78  ? 339 PRO A HG2    1 
ATOM   5306  H HG3    . PRO A 1 339 ? -31.553 -26.133 -32.207 1.00 35.78  ? 339 PRO A HG3    1 
ATOM   5307  H HD2    . PRO A 1 339 ? -32.104 -24.179 -30.409 1.00 32.60  ? 339 PRO A HD2    1 
ATOM   5308  H HD3    . PRO A 1 339 ? -32.998 -25.466 -30.744 1.00 32.60  ? 339 PRO A HD3    1 
ATOM   5309  N N      . VAL A 1 340 ? -28.046 -25.494 -28.590 1.00 23.11  ? 340 VAL A N      1 
ATOM   5310  C CA     . VAL A 1 340 ? -27.085 -24.558 -28.020 1.00 24.64  ? 340 VAL A CA     1 
ATOM   5311  C C      . VAL A 1 340 ? -26.902 -23.372 -28.960 1.00 24.49  ? 340 VAL A C      1 
ATOM   5312  O O      . VAL A 1 340 ? -26.671 -23.561 -30.153 1.00 27.85  ? 340 VAL A O      1 
ATOM   5313  C CB     . VAL A 1 340 ? -25.728 -25.239 -27.768 1.00 27.73  ? 340 VAL A CB     1 
ATOM   5314  C CG1    . VAL A 1 340 ? -24.720 -24.252 -27.189 1.00 26.68  ? 340 VAL A CG1    1 
ATOM   5315  C CG2    . VAL A 1 340 ? -25.909 -26.424 -26.838 1.00 30.97  ? 340 VAL A CG2    1 
ATOM   5316  H H      . VAL A 1 340 ? -27.713 -26.260 -28.796 1.00 27.73  ? 340 VAL A H      1 
ATOM   5317  H HA     . VAL A 1 340 ? -27.422 -24.227 -27.173 1.00 29.57  ? 340 VAL A HA     1 
ATOM   5318  H HB     . VAL A 1 340 ? -25.377 -25.568 -28.610 1.00 33.28  ? 340 VAL A HB     1 
ATOM   5319  H HG11   . VAL A 1 340 ? -23.960 -24.746 -26.843 1.00 32.01  ? 340 VAL A HG11   1 
ATOM   5320  H HG12   . VAL A 1 340 ? -24.429 -23.647 -27.889 1.00 32.01  ? 340 VAL A HG12   1 
ATOM   5321  H HG13   . VAL A 1 340 ? -25.143 -23.753 -26.472 1.00 32.01  ? 340 VAL A HG13   1 
ATOM   5322  H HG21   . VAL A 1 340 ? -25.041 -26.815 -26.654 1.00 37.17  ? 340 VAL A HG21   1 
ATOM   5323  H HG22   . VAL A 1 340 ? -26.316 -26.117 -26.013 1.00 37.17  ? 340 VAL A HG22   1 
ATOM   5324  H HG23   . VAL A 1 340 ? -26.482 -27.080 -27.266 1.00 37.17  ? 340 VAL A HG23   1 
ATOM   5325  N N      . GLY A 1 341 ? -27.008 -22.162 -28.413 1.00 24.02  ? 341 GLY A N      1 
ATOM   5326  C CA     . GLY A 1 341 ? -26.847 -20.947 -29.189 1.00 24.80  ? 341 GLY A CA     1 
ATOM   5327  C C      . GLY A 1 341 ? -25.394 -20.554 -29.392 1.00 19.95  ? 341 GLY A C      1 
ATOM   5328  O O      . GLY A 1 341 ? -24.474 -21.287 -29.026 1.00 22.14  ? 341 GLY A O      1 
ATOM   5329  H H      . GLY A 1 341 ? -27.175 -22.023 -27.581 1.00 28.83  ? 341 GLY A H      1 
ATOM   5330  H HA2    . GLY A 1 341 ? -27.255 -21.066 -30.061 1.00 29.76  ? 341 GLY A HA2    1 
ATOM   5331  H HA3    . GLY A 1 341 ? -27.294 -20.215 -28.744 1.00 29.76  ? 341 GLY A HA3    1 
ATOM   5332  N N      . GLY A 1 342 ? -25.190 -19.379 -29.972 1.00 20.23  ? 342 GLY A N      1 
ATOM   5333  C CA     . GLY A 1 342 ? -23.861 -18.968 -30.380 1.00 21.70  ? 342 GLY A CA     1 
ATOM   5334  C C      . GLY A 1 342 ? -22.963 -18.453 -29.273 1.00 19.04  ? 342 GLY A C      1 
ATOM   5335  O O      . GLY A 1 342 ? -21.741 -18.458 -29.433 1.00 19.19  ? 342 GLY A O      1 
ATOM   5336  H H      . GLY A 1 342 ? -25.806 -18.803 -30.140 1.00 24.28  ? 342 GLY A H      1 
ATOM   5337  H HA2    . GLY A 1 342 ? -23.415 -19.721 -30.797 1.00 26.04  ? 342 GLY A HA2    1 
ATOM   5338  H HA3    . GLY A 1 342 ? -23.943 -18.266 -31.044 1.00 26.04  ? 342 GLY A HA3    1 
ATOM   5339  N N      . HIS A 1 343 ? -23.548 -18.000 -28.159 1.00 17.89  ? 343 HIS A N      1 
ATOM   5340  C CA     . HIS A 1 343 ? -22.790 -17.219 -27.186 1.00 14.89  ? 343 HIS A CA     1 
ATOM   5341  C C      . HIS A 1 343 ? -22.956 -17.693 -25.754 1.00 18.23  ? 343 HIS A C      1 
ATOM   5342  O O      . HIS A 1 343 ? -22.289 -17.177 -24.869 1.00 19.59  ? 343 HIS A O      1 
ATOM   5343  C CB     . HIS A 1 343 ? -23.211 -15.755 -27.268 1.00 17.90  ? 343 HIS A CB     1 
ATOM   5344  C CG     . HIS A 1 343 ? -24.580 -15.502 -26.725 1.00 19.54  ? 343 HIS A CG     1 
ATOM   5345  N ND1    . HIS A 1 343 ? -25.723 -15.968 -27.338 1.00 23.65  ? 343 HIS A ND1    1 
ATOM   5346  C CD2    . HIS A 1 343 ? -24.990 -14.854 -25.609 1.00 23.10  ? 343 HIS A CD2    1 
ATOM   5347  C CE1    . HIS A 1 343 ? -26.778 -15.605 -26.631 1.00 26.51  ? 343 HIS A CE1    1 
ATOM   5348  N NE2    . HIS A 1 343 ? -26.360 -14.921 -25.580 1.00 21.23  ? 343 HIS A NE2    1 
ATOM   5349  H H      . HIS A 1 343 ? -24.371 -18.131 -27.948 1.00 21.47  ? 343 HIS A H      1 
ATOM   5350  H HA     . HIS A 1 343 ? -21.845 -17.262 -27.395 1.00 17.86  ? 343 HIS A HA     1 
ATOM   5351  H HB2    . HIS A 1 343 ? -22.584 -15.220 -26.756 1.00 21.48  ? 343 HIS A HB2    1 
ATOM   5352  H HB3    . HIS A 1 343 ? -23.202 -15.475 -28.196 1.00 21.48  ? 343 HIS A HB3    1 
ATOM   5353  H HD2    . HIS A 1 343 ? -24.445 -14.428 -24.987 1.00 27.72  ? 343 HIS A HD2    1 
ATOM   5354  H HE1    . HIS A 1 343 ? -27.664 -15.793 -26.840 1.00 31.82  ? 343 HIS A HE1    1 
ATOM   5355  H HE2    . HIS A 1 343 ? -26.864 -14.583 -24.971 1.00 25.48  ? 343 HIS A HE2    1 
ATOM   5356  N N      . ALA A 1 344 ? -23.825 -18.674 -25.520 1.00 17.48  ? 344 ALA A N      1 
ATOM   5357  C CA     . ALA A 1 344 ? -24.147 -19.065 -24.155 1.00 16.22  ? 344 ALA A CA     1 
ATOM   5358  C C      . ALA A 1 344 ? -24.817 -20.425 -24.093 1.00 16.21  ? 344 ALA A C      1 
ATOM   5359  O O      . ALA A 1 344 ? -25.391 -20.890 -25.077 1.00 18.11  ? 344 ALA A O      1 
ATOM   5360  C CB     . ALA A 1 344 ? -25.045 -18.043 -23.523 1.00 16.71  ? 344 ALA A CB     1 
ATOM   5361  H H      . ALA A 1 344 ? -24.236 -19.123 -26.127 1.00 20.97  ? 344 ALA A H      1 
ATOM   5362  H HA     . ALA A 1 344 ? -23.328 -19.111 -23.640 1.00 19.46  ? 344 ALA A HA     1 
ATOM   5363  H HB1    . ALA A 1 344 ? -25.243 -18.316 -22.614 1.00 20.05  ? 344 ALA A HB1    1 
ATOM   5364  H HB2    . ALA A 1 344 ? -24.593 -17.185 -23.520 1.00 20.05  ? 344 ALA A HB2    1 
ATOM   5365  H HB3    . ALA A 1 344 ? -25.865 -17.983 -24.037 1.00 20.05  ? 344 ALA A HB3    1 
ATOM   5366  N N      . VAL A 1 345 ? -24.733 -21.026 -22.913 1.00 15.03  ? 345 VAL A N      1 
ATOM   5367  C CA     . VAL A 1 345 ? -25.460 -22.240 -22.565 1.00 16.29  ? 345 VAL A CA     1 
ATOM   5368  C C      . VAL A 1 345 ? -26.396 -21.886 -21.406 1.00 23.57  ? 345 VAL A C      1 
ATOM   5369  O O      . VAL A 1 345 ? -25.967 -21.265 -20.431 1.00 20.83  ? 345 VAL A O      1 
ATOM   5370  C CB     . VAL A 1 345 ? -24.499 -23.373 -22.167 1.00 17.18  ? 345 VAL A CB     1 
ATOM   5371  C CG1    . VAL A 1 345 ? -25.273 -24.603 -21.671 1.00 18.29  ? 345 VAL A CG1    1 
ATOM   5372  C CG2    . VAL A 1 345 ? -23.583 -23.750 -23.350 1.00 18.47  ? 345 VAL A CG2    1 
ATOM   5373  H H      . VAL A 1 345 ? -24.240 -20.736 -22.271 1.00 18.04  ? 345 VAL A H      1 
ATOM   5374  H HA     . VAL A 1 345 ? -25.995 -22.537 -23.317 1.00 19.54  ? 345 VAL A HA     1 
ATOM   5375  H HB     . VAL A 1 345 ? -23.935 -23.064 -21.441 1.00 20.62  ? 345 VAL A HB     1 
ATOM   5376  H HG11   . VAL A 1 345 ? -24.665 -25.357 -21.622 1.00 21.95  ? 345 VAL A HG11   1 
ATOM   5377  H HG12   . VAL A 1 345 ? -25.639 -24.416 -20.792 1.00 21.95  ? 345 VAL A HG12   1 
ATOM   5378  H HG13   . VAL A 1 345 ? -25.990 -24.797 -22.295 1.00 21.95  ? 345 VAL A HG13   1 
ATOM   5379  H HG21   . VAL A 1 345 ? -22.999 -24.475 -23.078 1.00 22.16  ? 345 VAL A HG21   1 
ATOM   5380  H HG22   . VAL A 1 345 ? -24.133 -24.030 -24.098 1.00 22.16  ? 345 VAL A HG22   1 
ATOM   5381  H HG23   . VAL A 1 345 ? -23.055 -22.976 -23.600 1.00 22.16  ? 345 VAL A HG23   1 
ATOM   5382  N N      . PHE A 1 346 ? -27.669 -22.253 -21.529 1.00 20.39  ? 346 PHE A N      1 
ATOM   5383  C CA     . PHE A 1 346 ? -28.652 -22.005 -20.475 1.00 22.67  ? 346 PHE A CA     1 
ATOM   5384  C C      . PHE A 1 346 ? -29.008 -23.315 -19.772 1.00 25.61  ? 346 PHE A C      1 
ATOM   5385  O O      . PHE A 1 346 ? -29.552 -24.228 -20.395 1.00 22.52  ? 346 PHE A O      1 
ATOM   5386  C CB     . PHE A 1 346 ? -29.930 -21.366 -21.044 1.00 19.14  ? 346 PHE A CB     1 
ATOM   5387  C CG     . PHE A 1 346 ? -29.752 -19.970 -21.578 1.00 22.03  ? 346 PHE A CG     1 
ATOM   5388  C CD1    . PHE A 1 346 ? -29.110 -19.751 -22.785 1.00 23.60  ? 346 PHE A CD1    1 
ATOM   5389  C CD2    . PHE A 1 346 ? -30.284 -18.882 -20.898 1.00 25.91  ? 346 PHE A CD2    1 
ATOM   5390  C CE1    . PHE A 1 346 ? -28.963 -18.468 -23.291 1.00 28.93  ? 346 PHE A CE1    1 
ATOM   5391  C CE2    . PHE A 1 346 ? -30.144 -17.603 -21.395 1.00 24.32  ? 346 PHE A CE2    1 
ATOM   5392  C CZ     . PHE A 1 346 ? -29.481 -17.394 -22.602 1.00 25.57  ? 346 PHE A CZ     1 
ATOM   5393  H H      . PHE A 1 346 ? -27.992 -22.651 -22.219 1.00 24.47  ? 346 PHE A H      1 
ATOM   5394  H HA     . PHE A 1 346 ? -28.285 -21.398 -19.814 1.00 27.20  ? 346 PHE A HA     1 
ATOM   5395  H HB2    . PHE A 1 346 ? -30.254 -21.919 -21.771 1.00 22.97  ? 346 PHE A HB2    1 
ATOM   5396  H HB3    . PHE A 1 346 ? -30.597 -21.328 -20.341 1.00 22.97  ? 346 PHE A HB3    1 
ATOM   5397  H HD1    . PHE A 1 346 ? -28.757 -20.472 -23.254 1.00 28.31  ? 346 PHE A HD1    1 
ATOM   5398  H HD2    . PHE A 1 346 ? -30.727 -19.016 -20.091 1.00 31.09  ? 346 PHE A HD2    1 
ATOM   5399  H HE1    . PHE A 1 346 ? -28.520 -18.334 -24.097 1.00 34.71  ? 346 PHE A HE1    1 
ATOM   5400  H HE2    . PHE A 1 346 ? -30.494 -16.881 -20.925 1.00 29.18  ? 346 PHE A HE2    1 
ATOM   5401  H HZ     . PHE A 1 346 ? -29.384 -16.532 -22.938 1.00 30.68  ? 346 PHE A HZ     1 
ATOM   5402  N N      . LEU A 1 347 ? -28.681 -23.409 -18.486 1.00 21.65  ? 347 LEU A N      1 
ATOM   5403  C CA     . LEU A 1 347 ? -29.115 -24.525 -17.644 1.00 18.53  ? 347 LEU A CA     1 
ATOM   5404  C C      . LEU A 1 347 ? -30.590 -24.382 -17.289 1.00 22.76  ? 347 LEU A C      1 
ATOM   5405  O O      . LEU A 1 347 ? -31.038 -23.295 -16.947 1.00 21.21  ? 347 LEU A O      1 
ATOM   5406  C CB     . LEU A 1 347 ? -28.302 -24.583 -16.352 1.00 19.01  ? 347 LEU A CB     1 
ATOM   5407  C CG     . LEU A 1 347 ? -26.781 -24.651 -16.469 1.00 21.91  ? 347 LEU A CG     1 
ATOM   5408  C CD1    . LEU A 1 347 ? -26.155 -24.658 -15.088 1.00 22.76  ? 347 LEU A CD1    1 
ATOM   5409  C CD2    . LEU A 1 347 ? -26.354 -25.884 -17.245 1.00 24.65  ? 347 LEU A CD2    1 
ATOM   5410  H H      . LEU A 1 347 ? -28.200 -22.830 -18.070 1.00 25.98  ? 347 LEU A H      1 
ATOM   5411  H HA     . LEU A 1 347 ? -28.993 -25.360 -18.122 1.00 22.24  ? 347 LEU A HA     1 
ATOM   5412  H HB2    . LEU A 1 347 ? -28.511 -23.791 -15.832 1.00 22.81  ? 347 LEU A HB2    1 
ATOM   5413  H HB3    . LEU A 1 347 ? -28.583 -25.369 -15.858 1.00 22.81  ? 347 LEU A HB3    1 
ATOM   5414  H HG     . LEU A 1 347 ? -26.461 -23.868 -16.943 1.00 26.30  ? 347 LEU A HG     1 
ATOM   5415  H HD11   . LEU A 1 347 ? -25.190 -24.633 -15.179 1.00 27.31  ? 347 LEU A HD11   1 
ATOM   5416  H HD12   . LEU A 1 347 ? -26.462 -23.878 -14.599 1.00 27.31  ? 347 LEU A HD12   1 
ATOM   5417  H HD13   . LEU A 1 347 ? -26.424 -25.466 -14.624 1.00 27.31  ? 347 LEU A HD13   1 
ATOM   5418  H HD21   . LEU A 1 347 ? -25.385 -25.932 -17.252 1.00 29.58  ? 347 LEU A HD21   1 
ATOM   5419  H HD22   . LEU A 1 347 ? -26.721 -26.671 -16.813 1.00 29.58  ? 347 LEU A HD22   1 
ATOM   5420  H HD23   . LEU A 1 347 ? -26.689 -25.818 -18.153 1.00 29.58  ? 347 LEU A HD23   1 
ATOM   5421  N N      . ASP A 1 348 ? -31.339 -25.479 -17.354 1.00 22.20  ? 348 ASP A N      1 
ATOM   5422  C CA     . ASP A 1 348 ? -32.730 -25.482 -16.903 1.00 27.64  ? 348 ASP A CA     1 
ATOM   5423  C C      . ASP A 1 348 ? -32.749 -25.792 -15.415 1.00 23.09  ? 348 ASP A C      1 
ATOM   5424  O O      . ASP A 1 348 ? -32.693 -26.952 -15.016 1.00 23.00  ? 348 ASP A O      1 
ATOM   5425  C CB     . ASP A 1 348 ? -33.568 -26.510 -17.677 1.00 28.53  ? 348 ASP A CB     1 
ATOM   5426  C CG     . ASP A 1 348 ? -35.052 -26.473 -17.300 1.00 33.71  ? 348 ASP A CG     1 
ATOM   5427  O OD1    . ASP A 1 348 ? -35.410 -25.898 -16.248 1.00 32.47  ? 348 ASP A OD1    1 
ATOM   5428  O OD2    . ASP A 1 348 ? -35.870 -27.015 -18.072 1.00 36.78  ? 348 ASP A OD2    1 
ATOM   5429  H H      . ASP A 1 348 ? -31.066 -26.237 -17.656 1.00 26.65  ? 348 ASP A H      1 
ATOM   5430  H HA     . ASP A 1 348 ? -33.123 -24.606 -17.040 1.00 33.17  ? 348 ASP A HA     1 
ATOM   5431  H HB2    . ASP A 1 348 ? -33.496 -26.324 -18.626 1.00 34.23  ? 348 ASP A HB2    1 
ATOM   5432  H HB3    . ASP A 1 348 ? -33.232 -27.400 -17.488 1.00 34.23  ? 348 ASP A HB3    1 
ATOM   5433  N N      . ALA A 1 349 ? -32.839 -24.751 -14.595 1.00 24.34  ? 349 ALA A N      1 
ATOM   5434  C CA     . ALA A 1 349 ? -32.709 -24.920 -13.161 1.00 25.12  ? 349 ALA A CA     1 
ATOM   5435  C C      . ALA A 1 349 ? -33.922 -25.632 -12.590 1.00 25.39  ? 349 ALA A C      1 
ATOM   5436  O O      . ALA A 1 349 ? -33.844 -26.229 -11.521 1.00 29.46  ? 349 ALA A O      1 
ATOM   5437  C CB     . ALA A 1 349 ? -32.513 -23.569 -12.479 1.00 30.18  ? 349 ALA A CB     1 
ATOM   5438  H H      . ALA A 1 349 ? -32.975 -23.940 -14.846 1.00 29.21  ? 349 ALA A H      1 
ATOM   5439  H HA     . ALA A 1 349 ? -31.928 -25.464 -12.977 1.00 30.14  ? 349 ALA A HA     1 
ATOM   5440  H HB1    . ALA A 1 349 ? -32.439 -23.707 -11.522 1.00 36.22  ? 349 ALA A HB1    1 
ATOM   5441  H HB2    . ALA A 1 349 ? -31.702 -23.159 -12.818 1.00 36.22  ? 349 ALA A HB2    1 
ATOM   5442  H HB3    . ALA A 1 349 ? -33.276 -23.004 -12.674 1.00 36.22  ? 349 ALA A HB3    1 
ATOM   5443  N N      . ARG A 1 350 ? -35.046 -25.559 -13.292 1.00 26.64  ? 350 ARG A N      1 
ATOM   5444  C CA     . ARG A 1 350 ? -36.264 -26.189 -12.800 1.00 28.54  ? 350 ARG A CA     1 
ATOM   5445  C C      . ARG A 1 350 ? -36.086 -27.699 -12.738 1.00 30.93  ? 350 ARG A C      1 
ATOM   5446  O O      . ARG A 1 350 ? -36.450 -28.337 -11.750 1.00 33.97  ? 350 ARG A O      1 
ATOM   5447  C CB     . ARG A 1 350 ? -37.451 -25.825 -13.685 1.00 30.04  ? 350 ARG A CB     1 
ATOM   5448  C CG     . ARG A 1 350 ? -38.787 -26.231 -13.103 1.00 42.12  ? 350 ARG A CG     1 
ATOM   5449  C CD     . ARG A 1 350 ? -39.911 -26.015 -14.094 1.00 52.53  ? 350 ARG A CD     1 
ATOM   5450  N NE     . ARG A 1 350 ? -39.930 -24.659 -14.649 1.00 43.15  ? 350 ARG A NE     1 
ATOM   5451  C CZ     . ARG A 1 350 ? -40.590 -23.635 -14.117 1.00 47.19  ? 350 ARG A CZ     1 
ATOM   5452  N NH1    . ARG A 1 350 ? -41.288 -23.785 -12.993 1.00 49.57  ? 350 ARG A NH1    1 
ATOM   5453  N NH2    . ARG A 1 350 ? -40.551 -22.449 -14.711 1.00 44.38  ? 350 ARG A NH2    1 
ATOM   5454  H H      . ARG A 1 350 ? -35.132 -25.156 -14.046 1.00 31.97  ? 350 ARG A H      1 
ATOM   5455  H HA     . ARG A 1 350 ? -36.447 -25.869 -11.903 1.00 34.25  ? 350 ARG A HA     1 
ATOM   5456  H HB2    . ARG A 1 350 ? -37.461 -24.864 -13.813 1.00 36.04  ? 350 ARG A HB2    1 
ATOM   5457  H HB3    . ARG A 1 350 ? -37.352 -26.271 -14.541 1.00 36.04  ? 350 ARG A HB3    1 
ATOM   5458  H HG2    . ARG A 1 350 ? -38.765 -27.172 -12.871 1.00 50.54  ? 350 ARG A HG2    1 
ATOM   5459  H HG3    . ARG A 1 350 ? -38.969 -25.695 -12.315 1.00 50.54  ? 350 ARG A HG3    1 
ATOM   5460  H HD2    . ARG A 1 350 ? -39.797 -26.634 -14.832 1.00 63.03  ? 350 ARG A HD2    1 
ATOM   5461  H HD3    . ARG A 1 350 ? -40.759 -26.182 -13.656 1.00 63.03  ? 350 ARG A HD3    1 
ATOM   5462  H HE     . ARG A 1 350 ? -39.483 -24.516 -15.369 1.00 51.78  ? 350 ARG A HE     1 
ATOM   5463  H HH11   . ARG A 1 350 ? -41.323 -24.549 -12.601 1.00 59.49  ? 350 ARG A HH11   1 
ATOM   5464  H HH12   . ARG A 1 350 ? -41.708 -23.113 -12.658 1.00 59.49  ? 350 ARG A HH12   1 
ATOM   5465  H HH21   . ARG A 1 350 ? -40.099 -22.345 -15.435 1.00 53.25  ? 350 ARG A HH21   1 
ATOM   5466  H HH22   . ARG A 1 350 ? -40.971 -21.782 -14.367 1.00 53.25  ? 350 ARG A HH22   1 
ATOM   5467  N N      . ARG A 1 351 ? -35.566 -28.278 -13.798 1.00 29.17  ? 351 ARG A N      1 
ATOM   5468  C CA     . ARG A 1 351 ? -35.226 -29.688 -13.860 1.00 24.74  ? 351 ARG A CA     1 
ATOM   5469  C C      . ARG A 1 351 ? -33.930 -30.072 -13.176 1.00 30.26  ? 351 ARG A C      1 
ATOM   5470  O O      . ARG A 1 351 ? -33.732 -31.164 -12.820 1.00 25.87  ? 351 ARG A O      1 
ATOM   5471  C CB     . ARG A 1 351 ? -35.230 -30.181 -15.277 1.00 29.27  ? 351 ARG A CB     1 
ATOM   5472  C CG     . ARG A 1 351 ? -36.589 -30.169 -15.903 1.00 32.78  ? 351 ARG A CG     1 
ATOM   5473  C CD     . ARG A 1 351 ? -36.669 -30.915 -17.202 1.00 38.46  ? 351 ARG A CD     1 
ATOM   5474  N NE     . ARG A 1 351 ? -36.025 -30.167 -18.226 1.00 36.86  ? 351 ARG A NE     1 
ATOM   5475  C CZ     . ARG A 1 351 ? -35.410 -30.678 -19.255 1.00 36.30  ? 351 ARG A CZ     1 
ATOM   5476  N NH1    . ARG A 1 351 ? -35.395 -31.959 -19.458 1.00 36.43  ? 351 ARG A NH1    1 
ATOM   5477  N NH2    . ARG A 1 351 ? -34.836 -29.880 -20.092 1.00 37.83  ? 351 ARG A NH2    1 
ATOM   5478  H H      . ARG A 1 351 ? -35.392 -27.858 -14.528 1.00 35.00  ? 351 ARG A H      1 
ATOM   5479  H HA     . ARG A 1 351 ? -35.928 -30.175 -13.402 1.00 29.69  ? 351 ARG A HA     1 
ATOM   5480  H HB2    . ARG A 1 351 ? -34.651 -29.613 -15.809 1.00 35.13  ? 351 ARG A HB2    1 
ATOM   5481  H HB3    . ARG A 1 351 ? -34.902 -31.094 -15.293 1.00 35.13  ? 351 ARG A HB3    1 
ATOM   5482  H HG2    . ARG A 1 351 ? -37.219 -30.577 -15.289 1.00 39.33  ? 351 ARG A HG2    1 
ATOM   5483  H HG3    . ARG A 1 351 ? -36.846 -29.249 -16.074 1.00 39.33  ? 351 ARG A HG3    1 
ATOM   5484  H HD2    . ARG A 1 351 ? -36.221 -31.769 -17.101 1.00 46.15  ? 351 ARG A HD2    1 
ATOM   5485  H HD3    . ARG A 1 351 ? -37.598 -31.043 -17.441 1.00 46.15  ? 351 ARG A HD3    1 
ATOM   5486  H HE     . ARG A 1 351 ? -36.043 -29.310 -18.161 1.00 44.23  ? 351 ARG A HE     1 
ATOM   5487  H HH11   . ARG A 1 351 ? -35.770 -32.495 -18.901 1.00 43.71  ? 351 ARG A HH11   1 
ATOM   5488  H HH12   . ARG A 1 351 ? -34.993 -32.276 -20.149 1.00 43.71  ? 351 ARG A HH12   1 
ATOM   5489  H HH21   . ARG A 1 351 ? -34.859 -29.030 -19.961 1.00 45.40  ? 351 ARG A HH21   1 
ATOM   5490  H HH22   . ARG A 1 351 ? -34.444 -30.197 -20.789 1.00 45.40  ? 351 ARG A HH22   1 
ATOM   5491  N N      . PHE A 1 352 ? -33.026 -29.146 -13.048 1.00 25.25  ? 352 PHE A N      1 
ATOM   5492  C CA     . PHE A 1 352 ? -31.820 -29.383 -12.260 1.00 24.94  ? 352 PHE A CA     1 
ATOM   5493  C C      . PHE A 1 352 ? -32.193 -29.605 -10.787 1.00 25.57  ? 352 PHE A C      1 
ATOM   5494  O O      . PHE A 1 352 ? -31.556 -30.387 -10.089 1.00 28.26  ? 352 PHE A O      1 
ATOM   5495  C CB     . PHE A 1 352 ? -30.859 -28.193 -12.393 1.00 24.97  ? 352 PHE A CB     1 
ATOM   5496  C CG     . PHE A 1 352 ? -29.414 -28.540 -12.203 1.00 23.97  ? 352 PHE A CG     1 
ATOM   5497  C CD1    . PHE A 1 352 ? -28.915 -28.846 -10.953 1.00 22.75  ? 352 PHE A CD1    1 
ATOM   5498  C CD2    . PHE A 1 352 ? -28.542 -28.522 -13.278 1.00 23.80  ? 352 PHE A CD2    1 
ATOM   5499  C CE1    . PHE A 1 352 ? -27.573 -29.155 -10.782 1.00 22.78  ? 352 PHE A CE1    1 
ATOM   5500  C CE2    . PHE A 1 352 ? -27.205 -28.825 -13.115 1.00 21.52  ? 352 PHE A CE2    1 
ATOM   5501  C CZ     . PHE A 1 352 ? -26.714 -29.138 -11.868 1.00 21.06  ? 352 PHE A CZ     1 
ATOM   5502  H H      . PHE A 1 352 ? -33.072 -28.364 -13.402 1.00 30.30  ? 352 PHE A H      1 
ATOM   5503  H HA     . PHE A 1 352 ? -31.370 -30.178 -12.587 1.00 29.93  ? 352 PHE A HA     1 
ATOM   5504  H HB2    . PHE A 1 352 ? -30.956 -27.813 -13.280 1.00 29.97  ? 352 PHE A HB2    1 
ATOM   5505  H HB3    . PHE A 1 352 ? -31.093 -27.529 -11.726 1.00 29.97  ? 352 PHE A HB3    1 
ATOM   5506  H HD1    . PHE A 1 352 ? -29.487 -28.858 -10.220 1.00 27.30  ? 352 PHE A HD1    1 
ATOM   5507  H HD2    . PHE A 1 352 ? -28.863 -28.310 -14.125 1.00 28.56  ? 352 PHE A HD2    1 
ATOM   5508  H HE1    . PHE A 1 352 ? -27.249 -29.366 -9.936  1.00 27.34  ? 352 PHE A HE1    1 
ATOM   5509  H HE2    . PHE A 1 352 ? -26.634 -28.815 -13.849 1.00 25.83  ? 352 PHE A HE2    1 
ATOM   5510  H HZ     . PHE A 1 352 ? -25.814 -29.345 -11.757 1.00 25.28  ? 352 PHE A HZ     1 
ATOM   5511  N N      . CYS A 1 353 ? -33.234 -28.908 -10.335 1.00 24.54  ? 353 CYS A N      1 
ATOM   5512  C CA     . CYS A 1 353 ? -33.608 -28.869 -8.922  1.00 27.65  ? 353 CYS A CA     1 
ATOM   5513  C C      . CYS A 1 353 ? -35.095 -29.175 -8.744  1.00 28.55  ? 353 CYS A C      1 
ATOM   5514  O O      . CYS A 1 353 ? -35.848 -28.348 -8.246  1.00 28.39  ? 353 CYS A O      1 
ATOM   5515  C CB     . CYS A 1 353 ? -33.286 -27.493 -8.325  1.00 31.63  ? 353 CYS A CB     1 
ATOM   5516  S SG     . CYS A 1 353 ? -31.538 -27.031 -8.403  1.00 31.98  ? 353 CYS A SG     1 
ATOM   5517  H H      . CYS A 1 353 ? -33.750 -28.439 -10.838 1.00 29.45  ? 353 CYS A H      1 
ATOM   5518  H HA     . CYS A 1 353 ? -33.104 -29.534 -8.429  1.00 33.18  ? 353 CYS A HA     1 
ATOM   5519  H HB2    . CYS A 1 353 ? -33.790 -26.819 -8.808  1.00 37.96  ? 353 CYS A HB2    1 
ATOM   5520  H HB3    . CYS A 1 353 ? -33.548 -27.491 -7.391  1.00 37.96  ? 353 CYS A HB3    1 
ATOM   5521  H HG     . CYS A 1 353 ? -31.399 -25.945 -7.912  1.00 38.38  ? 353 CYS A HG     1 
ATOM   5522  N N      . PRO A 1 354 ? -35.520 -30.380 -9.144  1.00 30.42  ? 354 PRO A N      1 
ATOM   5523  C CA     . PRO A 1 354 ? -36.951 -30.709 -9.135  1.00 29.81  ? 354 PRO A CA     1 
ATOM   5524  C C      . PRO A 1 354 ? -37.541 -30.729 -7.725  1.00 33.06  ? 354 PRO A C      1 
ATOM   5525  O O      . PRO A 1 354 ? -38.751 -30.609 -7.563  1.00 34.29  ? 354 PRO A O      1 
ATOM   5526  C CB     . PRO A 1 354 ? -36.989 -32.104 -9.765  1.00 34.23  ? 354 PRO A CB     1 
ATOM   5527  C CG     . PRO A 1 354 ? -35.659 -32.697 -9.433  1.00 35.40  ? 354 PRO A CG     1 
ATOM   5528  C CD     . PRO A 1 354 ? -34.685 -31.543 -9.487  1.00 32.67  ? 354 PRO A CD     1 
ATOM   5529  H HA     . PRO A 1 354 ? -37.449 -30.087 -9.689  1.00 35.77  ? 354 PRO A HA     1 
ATOM   5530  H HB2    . PRO A 1 354 ? -37.707 -32.624 -9.371  1.00 41.08  ? 354 PRO A HB2    1 
ATOM   5531  H HB3    . PRO A 1 354 ? -37.103 -32.028 -10.725 1.00 41.08  ? 354 PRO A HB3    1 
ATOM   5532  H HG2    . PRO A 1 354 ? -35.686 -33.081 -8.543  1.00 42.47  ? 354 PRO A HG2    1 
ATOM   5533  H HG3    . PRO A 1 354 ? -35.428 -33.371 -10.091 1.00 42.47  ? 354 PRO A HG3    1 
ATOM   5534  H HD2    . PRO A 1 354 ? -33.983 -31.662 -8.828  1.00 39.20  ? 354 PRO A HD2    1 
ATOM   5535  H HD3    . PRO A 1 354 ? -34.322 -31.448 -10.381 1.00 39.20  ? 354 PRO A HD3    1 
ATOM   5536  N N      . HIS A 1 355 ? -36.680 -30.887 -6.725  1.00 31.81  ? 355 HIS A N      1 
ATOM   5537  C CA     . HIS A 1 355 ? -37.095 -30.878 -5.324  1.00 34.80  ? 355 HIS A CA     1 
ATOM   5538  C C      . HIS A 1 355 ? -37.419 -29.476 -4.804  1.00 35.66  ? 355 HIS A C      1 
ATOM   5539  O O      . HIS A 1 355 ? -37.967 -29.329 -3.712  1.00 38.29  ? 355 HIS A O      1 
ATOM   5540  C CB     . HIS A 1 355 ? -36.003 -31.498 -4.456  1.00 35.69  ? 355 HIS A CB     1 
ATOM   5541  C CG     . HIS A 1 355 ? -34.694 -30.773 -4.525  1.00 36.41  ? 355 HIS A CG     1 
ATOM   5542  N ND1    . HIS A 1 355 ? -33.909 -30.756 -5.660  1.00 35.34  ? 355 HIS A ND1    1 
ATOM   5543  C CD2    . HIS A 1 355 ? -34.034 -30.036 -3.601  1.00 34.29  ? 355 HIS A CD2    1 
ATOM   5544  C CE1    . HIS A 1 355 ? -32.821 -30.042 -5.430  1.00 34.88  ? 355 HIS A CE1    1 
ATOM   5545  N NE2    . HIS A 1 355 ? -32.872 -29.594 -4.188  1.00 35.87  ? 355 HIS A NE2    1 
ATOM   5546  H H      . HIS A 1 355 ? -35.839 -31.009 -6.838  1.00 38.18  ? 355 HIS A H      1 
ATOM   5547  H HA     . HIS A 1 355 ? -37.893 -31.421 -5.230  1.00 41.76  ? 355 HIS A HA     1 
ATOM   5548  H HB2    . HIS A 1 355 ? -36.297 -31.492 -3.532  1.00 42.83  ? 355 HIS A HB2    1 
ATOM   5549  H HB3    . HIS A 1 355 ? -35.852 -32.411 -4.747  1.00 42.83  ? 355 HIS A HB3    1 
ATOM   5550  H HD2    . HIS A 1 355 ? -34.313 -29.863 -2.731  1.00 41.14  ? 355 HIS A HD2    1 
ATOM   5551  H HE1    . HIS A 1 355 ? -32.136 -29.882 -6.039  1.00 41.85  ? 355 HIS A HE1    1 
ATOM   5552  H HE2    . HIS A 1 355 ? -32.275 -29.104 -3.809  1.00 43.04  ? 355 HIS A HE2    1 
ATOM   5553  N N      . LEU A 1 356 ? -37.076 -28.451 -5.582  1.00 32.15  ? 356 LEU A N      1 
ATOM   5554  C CA     . LEU A 1 356 ? -37.340 -27.068 -5.196  1.00 35.26  ? 356 LEU A CA     1 
ATOM   5555  C C      . LEU A 1 356 ? -38.506 -26.513 -5.994  1.00 33.20  ? 356 LEU A C      1 
ATOM   5556  O O      . LEU A 1 356 ? -38.658 -26.808 -7.180  1.00 33.29  ? 356 LEU A O      1 
ATOM   5557  C CB     . LEU A 1 356 ? -36.099 -26.190 -5.412  1.00 30.99  ? 356 LEU A CB     1 
ATOM   5558  C CG     . LEU A 1 356 ? -34.833 -26.629 -4.678  1.00 32.31  ? 356 LEU A CG     1 
ATOM   5559  C CD1    . LEU A 1 356 ? -33.670 -25.683 -4.989  1.00 32.68  ? 356 LEU A CD1    1 
ATOM   5560  C CD2    . LEU A 1 356 ? -35.071 -26.705 -3.172  1.00 33.13  ? 356 LEU A CD2    1 
ATOM   5561  H H      . LEU A 1 356 ? -36.686 -28.530 -6.344  1.00 38.58  ? 356 LEU A H      1 
ATOM   5562  H HA     . LEU A 1 356 ? -37.575 -27.025 -4.257  1.00 42.31  ? 356 LEU A HA     1 
ATOM   5563  H HB2    . LEU A 1 356 ? -35.894 -26.179 -6.360  1.00 37.19  ? 356 LEU A HB2    1 
ATOM   5564  H HB3    . LEU A 1 356 ? -36.307 -25.290 -5.117  1.00 37.19  ? 356 LEU A HB3    1 
ATOM   5565  H HG     . LEU A 1 356 ? -34.585 -27.515 -4.984  1.00 38.77  ? 356 LEU A HG     1 
ATOM   5566  H HD11   . LEU A 1 356 ? -32.875 -26.000 -4.533  1.00 39.22  ? 356 LEU A HD11   1 
ATOM   5567  H HD12   . LEU A 1 356 ? -33.520 -25.672 -5.947  1.00 39.22  ? 356 LEU A HD12   1 
ATOM   5568  H HD13   . LEU A 1 356 ? -33.897 -24.792 -4.679  1.00 39.22  ? 356 LEU A HD13   1 
ATOM   5569  H HD21   . LEU A 1 356 ? -34.226 -26.874 -2.728  1.00 39.76  ? 356 LEU A HD21   1 
ATOM   5570  H HD22   . LEU A 1 356 ? -35.442 -25.862 -2.869  1.00 39.76  ? 356 LEU A HD22   1 
ATOM   5571  H HD23   . LEU A 1 356 ? -35.693 -27.426 -2.986  1.00 39.76  ? 356 LEU A HD23   1 
ATOM   5572  N N      . THR A 1 357 ? -39.334 -25.714 -5.333  1.00 30.07  ? 357 THR A N      1 
ATOM   5573  C CA     . THR A 1 357 ? -40.367 -24.956 -6.019  1.00 27.79  ? 357 THR A CA     1 
ATOM   5574  C C      . THR A 1 357 ? -39.736 -23.694 -6.584  1.00 34.79  ? 357 THR A C      1 
ATOM   5575  O O      . THR A 1 357 ? -38.664 -23.280 -6.141  1.00 33.93  ? 357 THR A O      1 
ATOM   5576  C CB     . THR A 1 357 ? -41.528 -24.579 -5.079  1.00 36.20  ? 357 THR A CB     1 
ATOM   5577  O OG1    . THR A 1 357 ? -41.103 -23.544 -4.185  1.00 41.55  ? 357 THR A OG1    1 
ATOM   5578  C CG2    . THR A 1 357 ? -41.983 -25.789 -4.275  1.00 38.39  ? 357 THR A CG2    1 
ATOM   5579  H H      . THR A 1 357 ? -39.317 -25.593 -4.482  1.00 36.09  ? 357 THR A H      1 
ATOM   5580  H HA     . THR A 1 357 ? -40.726 -25.478 -6.753  1.00 33.35  ? 357 THR A HA     1 
ATOM   5581  H HB     . THR A 1 357 ? -42.278 -24.262 -5.605  1.00 43.44  ? 357 THR A HB     1 
ATOM   5582  H HG1    . THR A 1 357 ? -41.732 -23.334 -3.669  1.00 49.86  ? 357 THR A HG1    1 
ATOM   5583  H HG21   . THR A 1 357 ? -42.785 -25.571 -3.774  1.00 46.06  ? 357 THR A HG21   1 
ATOM   5584  H HG22   . THR A 1 357 ? -42.176 -26.529 -4.872  1.00 46.06  ? 357 THR A HG22   1 
ATOM   5585  H HG23   . THR A 1 357 ? -41.287 -26.057 -3.655  1.00 46.06  ? 357 THR A HG23   1 
ATOM   5586  N N      . GLN A 1 358 ? -40.388 -23.077 -7.557  1.00 32.40  ? 358 GLN A N      1 
ATOM   5587  C CA     . GLN A 1 358 ? -39.848 -21.864 -8.140  1.00 42.44  ? 358 GLN A CA     1 
ATOM   5588  C C      . GLN A 1 358 ? -39.754 -20.753 -7.087  1.00 42.16  ? 358 GLN A C      1 
ATOM   5589  O O      . GLN A 1 358 ? -38.929 -19.846 -7.202  1.00 37.03  ? 358 GLN A O      1 
ATOM   5590  C CB     . GLN A 1 358 ? -40.697 -21.410 -9.322  1.00 39.48  ? 358 GLN A CB     1 
ATOM   5591  C CG     . GLN A 1 358 ? -39.963 -20.430 -10.215 1.00 44.79  ? 358 GLN A CG     1 
ATOM   5592  C CD     . GLN A 1 358 ? -40.697 -20.123 -11.502 1.00 46.02  ? 358 GLN A CD     1 
ATOM   5593  O OE1    . GLN A 1 358 ? -41.913 -20.283 -11.594 1.00 53.59  ? 358 GLN A OE1    1 
ATOM   5594  N NE2    . GLN A 1 358 ? -39.955 -19.669 -12.507 1.00 46.53  ? 358 GLN A NE2    1 
ATOM   5595  H H      . GLN A 1 358 ? -41.136 -23.337 -7.893  1.00 38.87  ? 358 GLN A H      1 
ATOM   5596  H HA     . GLN A 1 358 ? -38.952 -22.043 -8.466  1.00 50.92  ? 358 GLN A HA     1 
ATOM   5597  H HB2    . GLN A 1 358 ? -40.937 -22.183 -9.856  1.00 47.38  ? 358 GLN A HB2    1 
ATOM   5598  H HB3    . GLN A 1 358 ? -41.497 -20.974 -8.989  1.00 47.38  ? 358 GLN A HB3    1 
ATOM   5599  H HG2    . GLN A 1 358 ? -39.843 -19.596 -9.734  1.00 53.75  ? 358 GLN A HG2    1 
ATOM   5600  H HG3    . GLN A 1 358 ? -39.099 -20.804 -10.448 1.00 53.75  ? 358 GLN A HG3    1 
ATOM   5601  H HE21   . GLN A 1 358 ? -39.108 -19.565 -12.403 1.00 55.83  ? 358 GLN A HE21   1 
ATOM   5602  H HE22   . GLN A 1 358 ? -40.322 -19.479 -13.261 1.00 55.83  ? 358 GLN A HE22   1 
ATOM   5603  N N      . ASP A 1 359 ? -40.590 -20.847 -6.057  1.00 37.09  ? 359 ASP A N      1 
ATOM   5604  C CA     . ASP A 1 359 ? -40.608 -19.876 -4.964  1.00 40.02  ? 359 ASP A CA     1 
ATOM   5605  C C      . ASP A 1 359 ? -39.377 -19.961 -4.078  1.00 40.66  ? 359 ASP A C      1 
ATOM   5606  O O      . ASP A 1 359 ? -39.164 -19.100 -3.220  1.00 41.24  ? 359 ASP A O      1 
ATOM   5607  C CB     . ASP A 1 359 ? -41.846 -20.083 -4.097  1.00 47.58  ? 359 ASP A CB     1 
ATOM   5608  C CG     . ASP A 1 359 ? -43.121 -19.833 -4.848  1.00 63.13  ? 359 ASP A CG     1 
ATOM   5609  O OD1    . ASP A 1 359 ? -43.586 -20.748 -5.563  1.00 67.22  ? 359 ASP A OD1    1 
ATOM   5610  O OD2    . ASP A 1 359 ? -43.657 -18.713 -4.727  1.00 69.92  ? 359 ASP A OD2    1 
ATOM   5611  H H      . ASP A 1 359 ? -41.170 -21.475 -5.965  1.00 44.51  ? 359 ASP A H      1 
ATOM   5612  H HA     . ASP A 1 359 ? -40.648 -18.981 -5.337  1.00 48.02  ? 359 ASP A HA     1 
ATOM   5613  H HB2    . ASP A 1 359 ? -41.860 -20.999 -3.778  1.00 57.10  ? 359 ASP A HB2    1 
ATOM   5614  H HB3    . ASP A 1 359 ? -41.814 -19.469 -3.347  1.00 57.10  ? 359 ASP A HB3    1 
ATOM   5615  N N      . GLU A 1 360 ? -38.593 -21.019 -4.263  1.00 31.92  ? 360 GLU A N      1 
ATOM   5616  C CA     . GLU A 1 360 ? -37.358 -21.212 -3.514  1.00 35.79  ? 360 GLU A CA     1 
ATOM   5617  C C      . GLU A 1 360 ? -36.150 -20.834 -4.375  1.00 31.03  ? 360 GLU A C      1 
ATOM   5618  O O      . GLU A 1 360 ? -35.006 -21.055 -3.975  1.00 31.26  ? 360 GLU A O      1 
ATOM   5619  C CB     . GLU A 1 360 ? -37.245 -22.660 -3.028  1.00 33.93  ? 360 GLU A CB     1 
ATOM   5620  C CG     . GLU A 1 360 ? -38.245 -23.029 -1.934  1.00 41.85  ? 360 GLU A CG     1 
ATOM   5621  C CD     . GLU A 1 360 ? -38.269 -24.522 -1.641  1.00 47.10  ? 360 GLU A CD     1 
ATOM   5622  O OE1    . GLU A 1 360 ? -38.715 -25.289 -2.521  1.00 41.37  ? 360 GLU A OE1    1 
ATOM   5623  O OE2    . GLU A 1 360 ? -37.836 -24.932 -0.540  1.00 48.55  ? 360 GLU A OE2    1 
ATOM   5624  H H      . GLU A 1 360 ? -38.757 -21.650 -4.823  1.00 38.30  ? 360 GLU A H      1 
ATOM   5625  H HA     . GLU A 1 360 ? -37.358 -20.639 -2.732  1.00 42.95  ? 360 GLU A HA     1 
ATOM   5626  H HB2    . GLU A 1 360 ? -37.397 -23.254 -3.780  1.00 40.72  ? 360 GLU A HB2    1 
ATOM   5627  H HB3    . GLU A 1 360 ? -36.354 -22.802 -2.673  1.00 40.72  ? 360 GLU A HB3    1 
ATOM   5628  H HG2    . GLU A 1 360 ? -38.004 -22.566 -1.116  1.00 50.22  ? 360 GLU A HG2    1 
ATOM   5629  H HG3    . GLU A 1 360 ? -39.134 -22.764 -2.216  1.00 50.22  ? 360 GLU A HG3    1 
ATOM   5630  N N      . PHE A 1 361 ? -36.426 -20.289 -5.558  1.00 26.01  ? 361 PHE A N      1 
ATOM   5631  C CA     . PHE A 1 361 ? -35.413 -19.640 -6.400  1.00 32.20  ? 361 PHE A CA     1 
ATOM   5632  C C      . PHE A 1 361 ? -34.315 -20.601 -6.840  1.00 26.93  ? 361 PHE A C      1 
ATOM   5633  O O      . PHE A 1 361 ? -33.143 -20.385 -6.524  1.00 23.38  ? 361 PHE A O      1 
ATOM   5634  C CB     . PHE A 1 361 ? -34.783 -18.460 -5.648  1.00 28.83  ? 361 PHE A CB     1 
ATOM   5635  C CG     . PHE A 1 361 ? -35.785 -17.524 -5.030  1.00 30.17  ? 361 PHE A CG     1 
ATOM   5636  C CD1    . PHE A 1 361 ? -36.963 -17.214 -5.684  1.00 30.38  ? 361 PHE A CD1    1 
ATOM   5637  C CD2    . PHE A 1 361 ? -35.545 -16.963 -3.782  1.00 33.48  ? 361 PHE A CD2    1 
ATOM   5638  C CE1    . PHE A 1 361 ? -37.880 -16.352 -5.114  1.00 36.99  ? 361 PHE A CE1    1 
ATOM   5639  C CE2    . PHE A 1 361 ? -36.459 -16.105 -3.207  1.00 37.94  ? 361 PHE A CE2    1 
ATOM   5640  C CZ     . PHE A 1 361 ? -37.628 -15.799 -3.874  1.00 36.96  ? 361 PHE A CZ     1 
ATOM   5641  H H      . PHE A 1 361 ? -37.209 -20.280 -5.912  1.00 31.21  ? 361 PHE A H      1 
ATOM   5642  H HA     . PHE A 1 361 ? -35.842 -19.293 -7.198  1.00 38.65  ? 361 PHE A HA     1 
ATOM   5643  H HB2    . PHE A 1 361 ? -34.225 -18.803 -4.932  1.00 34.59  ? 361 PHE A HB2    1 
ATOM   5644  H HB3    . PHE A 1 361 ? -34.242 -17.947 -6.269  1.00 34.59  ? 361 PHE A HB3    1 
ATOM   5645  H HD1    . PHE A 1 361 ? -37.136 -17.582 -6.520  1.00 36.46  ? 361 PHE A HD1    1 
ATOM   5646  H HD2    . PHE A 1 361 ? -34.757 -17.165 -3.331  1.00 40.17  ? 361 PHE A HD2    1 
ATOM   5647  H HE1    . PHE A 1 361 ? -38.669 -16.148 -5.563  1.00 44.39  ? 361 PHE A HE1    1 
ATOM   5648  H HE2    . PHE A 1 361 ? -36.287 -15.733 -2.372  1.00 45.53  ? 361 PHE A HE2    1 
ATOM   5649  H HZ     . PHE A 1 361 ? -38.246 -15.221 -3.488  1.00 44.35  ? 361 PHE A HZ     1 
ATOM   5650  N N      . PRO A 1 362 ? -34.684 -21.670 -7.568  1.00 28.60  ? 362 PRO A N      1 
ATOM   5651  C CA     . PRO A 1 362 ? -33.680 -22.687 -7.901  1.00 25.63  ? 362 PRO A CA     1 
ATOM   5652  C C      . PRO A 1 362 ? -32.575 -22.162 -8.823  1.00 22.02  ? 362 PRO A C      1 
ATOM   5653  O O      . PRO A 1 362 ? -31.427 -22.553 -8.648  1.00 24.24  ? 362 PRO A O      1 
ATOM   5654  C CB     . PRO A 1 362 ? -34.503 -23.792 -8.588  1.00 30.36  ? 362 PRO A CB     1 
ATOM   5655  C CG     . PRO A 1 362 ? -35.716 -23.103 -9.096  1.00 30.43  ? 362 PRO A CG     1 
ATOM   5656  C CD     . PRO A 1 362 ? -36.013 -22.001 -8.115  1.00 27.78  ? 362 PRO A CD     1 
ATOM   5657  H HA     . PRO A 1 362 ? -33.280 -23.042 -7.092  1.00 30.76  ? 362 PRO A HA     1 
ATOM   5658  H HB2    . PRO A 1 362 ? -33.993 -24.174 -9.319  1.00 36.44  ? 362 PRO A HB2    1 
ATOM   5659  H HB3    . PRO A 1 362 ? -34.741 -24.474 -7.941  1.00 36.44  ? 362 PRO A HB3    1 
ATOM   5660  H HG2    . PRO A 1 362 ? -35.530 -22.735 -9.972  1.00 36.52  ? 362 PRO A HG2    1 
ATOM   5661  H HG3    . PRO A 1 362 ? -36.454 -23.731 -9.138  1.00 36.52  ? 362 PRO A HG3    1 
ATOM   5662  H HD2    . PRO A 1 362 ? -36.394 -21.234 -8.570  1.00 33.34  ? 362 PRO A HD2    1 
ATOM   5663  H HD3    . PRO A 1 362 ? -36.597 -22.323 -7.411  1.00 33.34  ? 362 PRO A HD3    1 
ATOM   5664  N N      . ALA A 1 363 ? -32.904 -21.291 -9.768  1.00 24.01  ? 363 ALA A N      1 
ATOM   5665  C CA     . ALA A 1 363 ? -31.880 -20.718 -10.636 1.00 24.18  ? 363 ALA A CA     1 
ATOM   5666  C C      . ALA A 1 363 ? -30.890 -19.887 -9.811  1.00 25.05  ? 363 ALA A C      1 
ATOM   5667  O O      . ALA A 1 363 ? -29.675 -19.988 -9.995  1.00 21.13  ? 363 ALA A O      1 
ATOM   5668  C CB     . ALA A 1 363 ? -32.513 -19.877 -11.730 1.00 27.61  ? 363 ALA A CB     1 
ATOM   5669  H H      . ALA A 1 363 ? -33.703 -21.017 -9.928  1.00 28.81  ? 363 ALA A H      1 
ATOM   5670  H HA     . ALA A 1 363 ? -31.386 -21.437 -11.059 1.00 29.01  ? 363 ALA A HA     1 
ATOM   5671  H HB1    . ALA A 1 363 ? -31.812 -19.514 -12.294 1.00 33.13  ? 363 ALA A HB1    1 
ATOM   5672  H HB2    . ALA A 1 363 ? -33.104 -20.438 -12.256 1.00 33.13  ? 363 ALA A HB2    1 
ATOM   5673  H HB3    . ALA A 1 363 ? -33.017 -19.155 -11.323 1.00 33.13  ? 363 ALA A HB3    1 
ATOM   5674  N N      . GLN A 1 364 ? -31.401 -19.102 -8.867  1.00 25.83  ? 364 GLN A N      1 
ATOM   5675  C CA     . GLN A 1 364 ? -30.518 -18.301 -8.023  1.00 25.29  ? 364 GLN A CA     1 
ATOM   5676  C C      . GLN A 1 364 ? -29.636 -19.209 -7.185  1.00 22.88  ? 364 GLN A C      1 
ATOM   5677  O O      . GLN A 1 364 ? -28.428 -18.987 -7.104  1.00 20.76  ? 364 GLN A O      1 
ATOM   5678  C CB     . GLN A 1 364 ? -31.306 -17.342 -7.122  1.00 26.36  ? 364 GLN A CB     1 
ATOM   5679  C CG     . GLN A 1 364 ? -30.445 -16.222 -6.546  1.00 25.76  ? 364 GLN A CG     1 
ATOM   5680  C CD     . GLN A 1 364 ? -30.157 -15.125 -7.558  1.00 30.36  ? 364 GLN A CD     1 
ATOM   5681  O OE1    . GLN A 1 364 ? -31.071 -14.475 -8.069  1.00 28.58  ? 364 GLN A OE1    1 
ATOM   5682  N NE2    . GLN A 1 364 ? -28.882 -14.927 -7.863  1.00 32.01  ? 364 GLN A NE2    1 
ATOM   5683  H H      . GLN A 1 364 ? -32.239 -19.015 -8.696  1.00 30.99  ? 364 GLN A H      1 
ATOM   5684  H HA     . GLN A 1 364 ? -29.941 -17.767 -8.591  1.00 30.35  ? 364 GLN A HA     1 
ATOM   5685  H HB2    . GLN A 1 364 ? -32.018 -16.936 -7.641  1.00 31.63  ? 364 GLN A HB2    1 
ATOM   5686  H HB3    . GLN A 1 364 ? -31.681 -17.843 -6.380  1.00 31.63  ? 364 GLN A HB3    1 
ATOM   5687  H HG2    . GLN A 1 364 ? -30.909 -15.822 -5.794  1.00 30.92  ? 364 GLN A HG2    1 
ATOM   5688  H HG3    . GLN A 1 364 ? -29.597 -16.592 -6.254  1.00 30.92  ? 364 GLN A HG3    1 
ATOM   5689  H HE21   . GLN A 1 364 ? -28.272 -15.407 -7.494  1.00 38.41  ? 364 GLN A HE21   1 
ATOM   5690  H HE22   . GLN A 1 364 ? -28.665 -14.318 -8.430  1.00 38.41  ? 364 GLN A HE22   1 
ATOM   5691  N N      . SER A 1 365 ? -30.209 -20.256 -6.584  1.00 20.98  ? 365 SER A N      1 
ATOM   5692  C CA     . SER A 1 365 ? -29.412 -21.119 -5.732  1.00 21.98  ? 365 SER A CA     1 
ATOM   5693  C C      . SER A 1 365 ? -28.406 -21.925 -6.540  1.00 21.89  ? 365 SER A C      1 
ATOM   5694  O O      . SER A 1 365 ? -27.286 -22.144 -6.083  1.00 21.63  ? 365 SER A O      1 
ATOM   5695  C CB     . SER A 1 365 ? -30.287 -22.076 -4.912  1.00 23.72  ? 365 SER A CB     1 
ATOM   5696  O OG     . SER A 1 365 ? -29.467 -22.812 -4.020  1.00 25.15  ? 365 SER A OG     1 
ATOM   5697  H H      . SER A 1 365 ? -31.037 -20.478 -6.655  1.00 25.17  ? 365 SER A H      1 
ATOM   5698  H HA     . SER A 1 365 ? -28.915 -20.567 -5.108  1.00 26.37  ? 365 SER A HA     1 
ATOM   5699  H HB2    . SER A 1 365 ? -30.934 -21.563 -4.403  1.00 28.47  ? 365 SER A HB2    1 
ATOM   5700  H HB3    . SER A 1 365 ? -30.740 -22.690 -5.511  1.00 28.47  ? 365 SER A HB3    1 
ATOM   5701  H HG     . SER A 1 365 ? -29.936 -23.347 -3.574  1.00 30.17  ? 365 SER A HG     1 
ATOM   5702  N N      . LEU A 1 366 ? -28.799 -22.370 -7.732  1.00 20.08  ? 366 LEU A N      1 
ATOM   5703  C CA     . LEU A 1 366 ? -27.890 -23.135 -8.575  1.00 22.51  ? 366 LEU A CA     1 
ATOM   5704  C C      . LEU A 1 366 ? -26.671 -22.280 -8.945  1.00 17.99  ? 366 LEU A C      1 
ATOM   5705  O O      . LEU A 1 366 ? -25.530 -22.757 -8.892  1.00 20.07  ? 366 LEU A O      1 
ATOM   5706  C CB     . LEU A 1 366 ? -28.607 -23.636 -9.835  1.00 23.44  ? 366 LEU A CB     1 
ATOM   5707  C CG     . LEU A 1 366 ? -27.758 -24.367 -10.874 1.00 21.61  ? 366 LEU A CG     1 
ATOM   5708  C CD1    . LEU A 1 366 ? -26.913 -25.446 -10.239 1.00 23.59  ? 366 LEU A CD1    1 
ATOM   5709  C CD2    . LEU A 1 366 ? -28.658 -24.970 -11.939 1.00 23.45  ? 366 LEU A CD2    1 
ATOM   5710  H H      . LEU A 1 366 ? -29.579 -22.243 -8.071  1.00 24.10  ? 366 LEU A H      1 
ATOM   5711  H HA     . LEU A 1 366 ? -27.576 -23.907 -8.079  1.00 27.02  ? 366 LEU A HA     1 
ATOM   5712  H HB2    . LEU A 1 366 ? -29.309 -24.246 -9.560  1.00 28.13  ? 366 LEU A HB2    1 
ATOM   5713  H HB3    . LEU A 1 366 ? -29.005 -22.871 -10.279 1.00 28.13  ? 366 LEU A HB3    1 
ATOM   5714  H HG     . LEU A 1 366 ? -27.164 -23.732 -11.304 1.00 25.93  ? 366 LEU A HG     1 
ATOM   5715  H HD11   . LEU A 1 366 ? -26.490 -25.967 -10.940 1.00 28.31  ? 366 LEU A HD11   1 
ATOM   5716  H HD12   . LEU A 1 366 ? -26.236 -25.035 -9.680  1.00 28.31  ? 366 LEU A HD12   1 
ATOM   5717  H HD13   . LEU A 1 366 ? -27.484 -26.018 -9.702  1.00 28.31  ? 366 LEU A HD13   1 
ATOM   5718  H HD21   . LEU A 1 366 ? -28.108 -25.425 -12.596 1.00 28.15  ? 366 LEU A HD21   1 
ATOM   5719  H HD22   . LEU A 1 366 ? -29.263 -25.601 -11.520 1.00 28.15  ? 366 LEU A HD22   1 
ATOM   5720  H HD23   . LEU A 1 366 ? -29.163 -24.259 -12.364 1.00 28.15  ? 366 LEU A HD23   1 
ATOM   5721  N N      . ALA A 1 367 ? -26.918 -21.025 -9.305  1.00 22.48  ? 367 ALA A N      1 
ATOM   5722  C CA     . ALA A 1 367 ? -25.832 -20.107 -9.660  1.00 20.81  ? 367 ALA A CA     1 
ATOM   5723  C C      . ALA A 1 367 ? -24.869 -19.930 -8.482  1.00 20.49  ? 367 ALA A C      1 
ATOM   5724  O O      . ALA A 1 367 ? -23.654 -19.954 -8.654  1.00 16.52  ? 367 ALA A O      1 
ATOM   5725  C CB     . ALA A 1 367 ? -26.384 -18.775 -10.103 1.00 21.20  ? 367 ALA A CB     1 
ATOM   5726  H H      . ALA A 1 367 ? -27.703 -20.677 -9.353  1.00 26.97  ? 367 ALA A H      1 
ATOM   5727  H HA     . ALA A 1 367 ? -25.331 -20.484 -10.401 1.00 24.98  ? 367 ALA A HA     1 
ATOM   5728  H HB1    . ALA A 1 367 ? -25.646 -18.188 -10.331 1.00 25.44  ? 367 ALA A HB1    1 
ATOM   5729  H HB2    . ALA A 1 367 ? -26.951 -18.911 -10.878 1.00 25.44  ? 367 ALA A HB2    1 
ATOM   5730  H HB3    . ALA A 1 367 ? -26.901 -18.391 -9.377  1.00 25.44  ? 367 ALA A HB3    1 
ATOM   5731  N N      . ALA A 1 368 ? -25.412 -19.783 -7.280  1.00 20.93  ? 368 ALA A N      1 
ATOM   5732  C CA     . ALA A 1 368 ? -24.571 -19.697 -6.090  1.00 22.25  ? 368 ALA A CA     1 
ATOM   5733  C C      . ALA A 1 368 ? -23.742 -20.966 -5.894  1.00 22.01  ? 368 ALA A C      1 
ATOM   5734  O O      . ALA A 1 368 ? -22.536 -20.892 -5.647  1.00 19.84  ? 368 ALA A O      1 
ATOM   5735  C CB     . ALA A 1 368 ? -25.429 -19.428 -4.851  1.00 24.10  ? 368 ALA A CB     1 
ATOM   5736  H H      . ALA A 1 368 ? -26.256 -19.731 -7.125  1.00 25.11  ? 368 ALA A H      1 
ATOM   5737  H HA     . ALA A 1 368 ? -23.957 -18.954 -6.194  1.00 26.70  ? 368 ALA A HA     1 
ATOM   5738  H HB1    . ALA A 1 368 ? -24.852 -19.374 -4.073  1.00 28.92  ? 368 ALA A HB1    1 
ATOM   5739  H HB2    . ALA A 1 368 ? -25.902 -18.590 -4.971  1.00 28.92  ? 368 ALA A HB2    1 
ATOM   5740  H HB3    . ALA A 1 368 ? -26.064 -20.154 -4.743  1.00 28.92  ? 368 ALA A HB3    1 
ATOM   5741  N N      . SER A 1 369 ? -24.375 -22.135 -6.016  1.00 19.90  ? 369 SER A N      1 
ATOM   5742  C CA     . SER A 1 369 ? -23.672 -23.397 -5.831  1.00 20.24  ? 369 SER A CA     1 
ATOM   5743  C C      . SER A 1 369 ? -22.558 -23.581 -6.856  1.00 19.20  ? 369 SER A C      1 
ATOM   5744  O O      . SER A 1 369 ? -21.480 -24.066 -6.523  1.00 17.52  ? 369 SER A O      1 
ATOM   5745  C CB     . SER A 1 369 ? -24.645 -24.579 -5.919  1.00 24.67  ? 369 SER A CB     1 
ATOM   5746  O OG     . SER A 1 369 ? -25.484 -24.624 -4.777  1.00 25.04  ? 369 SER A OG     1 
ATOM   5747  H H      . SER A 1 369 ? -25.210 -22.220 -6.205  1.00 23.88  ? 369 SER A H      1 
ATOM   5748  H HA     . SER A 1 369 ? -23.270 -23.407 -4.949  1.00 24.29  ? 369 SER A HA     1 
ATOM   5749  H HB2    . SER A 1 369 ? -25.195 -24.477 -6.712  1.00 29.60  ? 369 SER A HB2    1 
ATOM   5750  H HB3    . SER A 1 369 ? -24.137 -25.404 -5.971  1.00 29.60  ? 369 SER A HB3    1 
ATOM   5751  H HG     . SER A 1 369 ? -25.930 -23.914 -4.720  1.00 30.04  ? 369 SER A HG     1 
ATOM   5752  N N      . ILE A 1 370 ? -22.824 -23.209 -8.102  1.00 18.85  ? 370 ILE A N      1 
ATOM   5753  C CA     . ILE A 1 370 ? -21.797 -23.288 -9.130  1.00 18.79  ? 370 ILE A CA     1 
ATOM   5754  C C      . ILE A 1 370 ? -20.581 -22.454 -8.729  1.00 18.05  ? 370 ILE A C      1 
ATOM   5755  O O      . ILE A 1 370 ? -19.438 -22.918 -8.834  1.00 19.83  ? 370 ILE A O      1 
ATOM   5756  C CB     . ILE A 1 370 ? -22.340 -22.834 -10.503 1.00 20.59  ? 370 ILE A CB     1 
ATOM   5757  C CG1    . ILE A 1 370 ? -23.333 -23.875 -11.038 1.00 20.39  ? 370 ILE A CG1    1 
ATOM   5758  C CG2    . ILE A 1 370 ? -21.183 -22.661 -11.521 1.00 19.46  ? 370 ILE A CG2    1 
ATOM   5759  C CD1    . ILE A 1 370 ? -24.052 -23.452 -12.298 1.00 21.59  ? 370 ILE A CD1    1 
ATOM   5760  H H      . ILE A 1 370 ? -23.583 -22.911 -8.375  1.00 22.62  ? 370 ILE A H      1 
ATOM   5761  H HA     . ILE A 1 370 ? -21.510 -24.211 -9.215  1.00 22.55  ? 370 ILE A HA     1 
ATOM   5762  H HB     . ILE A 1 370 ? -22.798 -21.985 -10.397 1.00 24.71  ? 370 ILE A HB     1 
ATOM   5763  H HG12   . ILE A 1 370 ? -22.848 -24.691 -11.237 1.00 24.47  ? 370 ILE A HG12   1 
ATOM   5764  H HG13   . ILE A 1 370 ? -24.001 -24.052 -10.359 1.00 24.47  ? 370 ILE A HG13   1 
ATOM   5765  H HG21   . ILE A 1 370 ? -21.550 -22.577 -12.414 1.00 23.35  ? 370 ILE A HG21   1 
ATOM   5766  H HG22   . ILE A 1 370 ? -20.681 -21.861 -11.301 1.00 23.35  ? 370 ILE A HG22   1 
ATOM   5767  H HG23   . ILE A 1 370 ? -20.605 -23.439 -11.475 1.00 23.35  ? 370 ILE A HG23   1 
ATOM   5768  H HD11   . ILE A 1 370 ? -24.826 -24.022 -12.425 1.00 25.91  ? 370 ILE A HD11   1 
ATOM   5769  H HD12   . ILE A 1 370 ? -24.333 -22.528 -12.205 1.00 25.91  ? 370 ILE A HD12   1 
ATOM   5770  H HD13   . ILE A 1 370 ? -23.449 -23.540 -13.053 1.00 25.91  ? 370 ILE A HD13   1 
ATOM   5771  N N      . TYR A 1 371 ? -20.812 -21.239 -8.248  1.00 15.91  ? 371 TYR A N      1 
ATOM   5772  C CA     . TYR A 1 371 ? -19.684 -20.396 -7.840  1.00 19.65  ? 371 TYR A CA     1 
ATOM   5773  C C      . TYR A 1 371 ? -18.915 -21.044 -6.683  1.00 18.72  ? 371 TYR A C      1 
ATOM   5774  O O      . TYR A 1 371 ? -17.684 -21.133 -6.695  1.00 19.28  ? 371 TYR A O      1 
ATOM   5775  C CB     . TYR A 1 371 ? -20.138 -18.990 -7.442  1.00 21.63  ? 371 TYR A CB     1 
ATOM   5776  C CG     . TYR A 1 371 ? -18.995 -18.228 -6.822  1.00 21.92  ? 371 TYR A CG     1 
ATOM   5777  C CD1    . TYR A 1 371 ? -17.974 -17.712 -7.609  1.00 17.10  ? 371 TYR A CD1    1 
ATOM   5778  C CD2    . TYR A 1 371 ? -18.910 -18.065 -5.447  1.00 20.92  ? 371 TYR A CD2    1 
ATOM   5779  C CE1    . TYR A 1 371 ? -16.906 -17.039 -7.042  1.00 17.79  ? 371 TYR A CE1    1 
ATOM   5780  C CE2    . TYR A 1 371 ? -17.853 -17.401 -4.873  1.00 19.60  ? 371 TYR A CE2    1 
ATOM   5781  C CZ     . TYR A 1 371 ? -16.854 -16.891 -5.665  1.00 21.53  ? 371 TYR A CZ     1 
ATOM   5782  O OH     . TYR A 1 371 ? -15.803 -16.235 -5.076  1.00 20.86  ? 371 TYR A OH     1 
ATOM   5783  H H      . TYR A 1 371 ? -21.588 -20.883 -8.148  1.00 19.09  ? 371 TYR A H      1 
ATOM   5784  H HA     . TYR A 1 371 ? -19.071 -20.310 -8.586  1.00 23.58  ? 371 TYR A HA     1 
ATOM   5785  H HB2    . TYR A 1 371 ? -20.436 -18.510 -8.231  1.00 25.96  ? 371 TYR A HB2    1 
ATOM   5786  H HB3    . TYR A 1 371 ? -20.855 -19.053 -6.792  1.00 25.96  ? 371 TYR A HB3    1 
ATOM   5787  H HD1    . TYR A 1 371 ? -18.009 -17.819 -8.532  1.00 20.52  ? 371 TYR A HD1    1 
ATOM   5788  H HD2    . TYR A 1 371 ? -19.579 -18.414 -4.904  1.00 25.11  ? 371 TYR A HD2    1 
ATOM   5789  H HE1    . TYR A 1 371 ? -16.229 -16.695 -7.578  1.00 21.35  ? 371 TYR A HE1    1 
ATOM   5790  H HE2    . TYR A 1 371 ? -17.814 -17.298 -3.950  1.00 23.52  ? 371 TYR A HE2    1 
ATOM   5791  H HH     . TYR A 1 371 ? -15.260 -15.978 -5.663  1.00 25.03  ? 371 TYR A HH     1 
ATOM   5792  N N      . MET A 1 372 ? -19.635 -21.524 -5.680  1.00 18.29  ? 372 MET A N      1 
ATOM   5793  C CA     . MET A 1 372 ? -18.963 -22.089 -4.520  1.00 18.34  ? 372 MET A CA     1 
ATOM   5794  C C      . MET A 1 372 ? -18.158 -23.326 -4.882  1.00 19.96  ? 372 MET A C      1 
ATOM   5795  O O      . MET A 1 372 ? -17.082 -23.554 -4.332  1.00 19.55  ? 372 MET A O      1 
ATOM   5796  C CB     . MET A 1 372 ? -19.984 -22.384 -3.431  1.00 21.06  ? 372 MET A CB     1 
ATOM   5797  C CG     . MET A 1 372 ? -20.543 -21.103 -2.858  1.00 21.05  ? 372 MET A CG     1 
ATOM   5798  S SD     . MET A 1 372 ? -21.628 -21.322 -1.421  1.00 24.44  ? 372 MET A SD     1 
ATOM   5799  C CE     . MET A 1 372 ? -23.099 -21.892 -2.244  1.00 24.40  ? 372 MET A CE     1 
ATOM   5800  H H      . MET A 1 372 ? -20.494 -21.535 -5.645  1.00 21.94  ? 372 MET A H      1 
ATOM   5801  H HA     . MET A 1 372 ? -18.352 -21.423 -4.168  1.00 22.01  ? 372 MET A HA     1 
ATOM   5802  H HB2    . MET A 1 372 ? -20.716 -22.897 -3.807  1.00 25.27  ? 372 MET A HB2    1 
ATOM   5803  H HB3    . MET A 1 372 ? -19.557 -22.879 -2.714  1.00 25.27  ? 372 MET A HB3    1 
ATOM   5804  H HG2    . MET A 1 372 ? -19.803 -20.539 -2.583  1.00 25.26  ? 372 MET A HG2    1 
ATOM   5805  H HG3    . MET A 1 372 ? -21.056 -20.653 -3.547  1.00 25.26  ? 372 MET A HG3    1 
ATOM   5806  H HE1    . MET A 1 372 ? -23.659 -22.349 -1.599  1.00 29.28  ? 372 MET A HE1    1 
ATOM   5807  H HE2    . MET A 1 372 ? -23.571 -21.130 -2.616  1.00 29.28  ? 372 MET A HE2    1 
ATOM   5808  H HE3    . MET A 1 372 ? -22.845 -22.505 -2.951  1.00 29.28  ? 372 MET A HE3    1 
ATOM   5809  N N      . GLU A 1 373 ? -18.656 -24.102 -5.839  1.00 23.46  ? 373 GLU A N      1 
ATOM   5810  C CA     . GLU A 1 373 ? -17.981 -25.325 -6.256  1.00 23.54  ? 373 GLU A CA     1 
ATOM   5811  C C      . GLU A 1 373 ? -16.725 -25.079 -7.116  1.00 23.35  ? 373 GLU A C      1 
ATOM   5812  O O      . GLU A 1 373 ? -15.773 -25.861 -7.039  1.00 21.80  ? 373 GLU A O      1 
ATOM   5813  C CB     . GLU A 1 373 ? -18.980 -26.212 -7.017  1.00 25.74  ? 373 GLU A CB     1 
ATOM   5814  C CG     . GLU A 1 373 ? -18.411 -27.511 -7.602  1.00 33.43  ? 373 GLU A CG     1 
ATOM   5815  C CD     . GLU A 1 373 ? -17.892 -28.467 -6.541  1.00 46.28  ? 373 GLU A CD     1 
ATOM   5816  O OE1    . GLU A 1 373 ? -18.501 -28.534 -5.450  1.00 41.70  ? 373 GLU A OE1    1 
ATOM   5817  O OE2    . GLU A 1 373 ? -16.874 -29.148 -6.805  1.00 47.57  ? 373 GLU A OE2    1 
ATOM   5818  H H      . GLU A 1 373 ? -19.386 -23.942 -6.264  1.00 28.15  ? 373 GLU A H      1 
ATOM   5819  H HA     . GLU A 1 373 ? -17.703 -25.810 -5.464  1.00 28.25  ? 373 GLU A HA     1 
ATOM   5820  H HB2    . GLU A 1 373 ? -19.697 -26.455 -6.411  1.00 30.89  ? 373 GLU A HB2    1 
ATOM   5821  H HB3    . GLU A 1 373 ? -19.343 -25.698 -7.755  1.00 30.89  ? 373 GLU A HB3    1 
ATOM   5822  H HG2    . GLU A 1 373 ? -19.114 -27.966 -8.091  1.00 40.12  ? 373 GLU A HG2    1 
ATOM   5823  H HG3    . GLU A 1 373 ? -17.679 -27.301 -8.202  1.00 40.12  ? 373 GLU A HG3    1 
ATOM   5824  N N      . THR A 1 374 ? -16.703 -23.996 -7.904  1.00 21.95  ? 374 THR A N      1 
ATOM   5825  C CA     . THR A 1 374 ? -15.679 -23.827 -8.952  1.00 19.42  ? 374 THR A CA     1 
ATOM   5826  C C      . THR A 1 374 ? -15.016 -22.457 -9.079  1.00 20.74  ? 374 THR A C      1 
ATOM   5827  O O      . THR A 1 374 ? -13.953 -22.346 -9.697  1.00 19.80  ? 374 THR A O      1 
ATOM   5828  C CB     . THR A 1 374 ? -16.262 -24.089 -10.341 1.00 18.52  ? 374 THR A CB     1 
ATOM   5829  O OG1    . THR A 1 374 ? -17.307 -23.140 -10.587 1.00 19.80  ? 374 THR A OG1    1 
ATOM   5830  C CG2    . THR A 1 374 ? -16.798 -25.504 -10.459 1.00 24.45  ? 374 THR A CG2    1 
ATOM   5831  H H      . THR A 1 374 ? -17.265 -23.347 -7.854  1.00 26.34  ? 374 THR A H      1 
ATOM   5832  H HA     . THR A 1 374 ? -14.970 -24.472 -8.810  1.00 23.31  ? 374 THR A HA     1 
ATOM   5833  H HB     . THR A 1 374 ? -15.565 -23.974 -11.006 1.00 22.23  ? 374 THR A HB     1 
ATOM   5834  H HG1    . THR A 1 374 ? -17.911 -23.222 -10.009 1.00 23.77  ? 374 THR A HG1    1 
ATOM   5835  H HG21   . THR A 1 374 ? -17.118 -25.662 -11.361 1.00 29.33  ? 374 THR A HG21   1 
ATOM   5836  H HG22   . THR A 1 374 ? -16.096 -26.142 -10.257 1.00 29.33  ? 374 THR A HG22   1 
ATOM   5837  H HG23   . THR A 1 374 ? -17.531 -25.634 -9.837  1.00 29.33  ? 374 THR A HG23   1 
ATOM   5838  N N      . GLY A 1 375 ? -15.660 -21.422 -8.558  1.00 17.19  ? 375 GLY A N      1 
ATOM   5839  C CA     . GLY A 1 375 ? -15.194 -20.057 -8.764  1.00 17.27  ? 375 GLY A CA     1 
ATOM   5840  C C      . GLY A 1 375 ? -15.727 -19.481 -10.066 1.00 20.47  ? 375 GLY A C      1 
ATOM   5841  O O      . GLY A 1 375 ? -15.271 -18.414 -10.507 1.00 17.32  ? 375 GLY A O      1 
ATOM   5842  H H      . GLY A 1 375 ? -16.372 -21.482 -8.079  1.00 20.63  ? 375 GLY A H      1 
ATOM   5843  H HA2    . GLY A 1 375 ? -15.497 -19.497 -8.032  1.00 20.73  ? 375 GLY A HA2    1 
ATOM   5844  H HA3    . GLY A 1 375 ? -14.225 -20.037 -8.787  1.00 20.73  ? 375 GLY A HA3    1 
ATOM   5845  N N      . VAL A 1 376 ? -16.679 -20.189 -10.681 1.00 15.78  ? 376 VAL A N      1 
ATOM   5846  C CA     . VAL A 1 376 ? -17.349 -19.735 -11.905 1.00 18.66  ? 376 VAL A CA     1 
ATOM   5847  C C      . VAL A 1 376 ? -18.589 -18.905 -11.587 1.00 19.08  ? 376 VAL A C      1 
ATOM   5848  O O      . VAL A 1 376 ? -19.465 -19.355 -10.849 1.00 20.58  ? 376 VAL A O      1 
ATOM   5849  C CB     . VAL A 1 376 ? -17.793 -20.930 -12.799 1.00 16.09  ? 376 VAL A CB     1 
ATOM   5850  C CG1    . VAL A 1 376 ? -18.546 -20.430 -14.033 1.00 18.70  ? 376 VAL A CG1    1 
ATOM   5851  C CG2    . VAL A 1 376 ? -16.609 -21.773 -13.195 1.00 16.00  ? 376 VAL A CG2    1 
ATOM   5852  H H      . VAL A 1 376 ? -16.963 -20.952 -10.406 1.00 18.94  ? 376 VAL A H      1 
ATOM   5853  H HA     . VAL A 1 376 ? -16.734 -19.191 -12.415 1.00 22.39  ? 376 VAL A HA     1 
ATOM   5854  H HB     . VAL A 1 376 ? -18.399 -21.491 -12.291 1.00 19.31  ? 376 VAL A HB     1 
ATOM   5855  H HG11   . VAL A 1 376 ? -18.577 -21.142 -14.691 1.00 22.44  ? 376 VAL A HG11   1 
ATOM   5856  H HG12   . VAL A 1 376 ? -19.448 -20.180 -13.778 1.00 22.44  ? 376 VAL A HG12   1 
ATOM   5857  H HG13   . VAL A 1 376 ? -18.078 -19.664 -14.399 1.00 22.44  ? 376 VAL A HG13   1 
ATOM   5858  H HG21   . VAL A 1 376 ? -16.928 -22.637 -13.498 1.00 19.20  ? 376 VAL A HG21   1 
ATOM   5859  H HG22   . VAL A 1 376 ? -16.132 -21.330 -13.913 1.00 19.20  ? 376 VAL A HG22   1 
ATOM   5860  H HG23   . VAL A 1 376 ? -16.026 -21.889 -12.429 1.00 19.20  ? 376 VAL A HG23   1 
ATOM   5861  N N      . ARG A 1 377 ? -18.674 -17.704 -12.146 1.00 15.14  ? 377 ARG A N      1 
ATOM   5862  C CA     . ARG A 1 377 ? -19.878 -16.895 -12.000 1.00 17.85  ? 377 ARG A CA     1 
ATOM   5863  C C      . ARG A 1 377 ? -20.790 -17.044 -13.205 1.00 18.62  ? 377 ARG A C      1 
ATOM   5864  O O      . ARG A 1 377 ? -20.344 -16.944 -14.352 1.00 17.85  ? 377 ARG A O      1 
ATOM   5865  C CB     . ARG A 1 377 ? -19.539 -15.414 -11.791 1.00 16.28  ? 377 ARG A CB     1 
ATOM   5866  C CG     . ARG A 1 377 ? -20.776 -14.523 -11.891 1.00 15.28  ? 377 ARG A CG     1 
ATOM   5867  C CD     . ARG A 1 377 ? -20.642 -13.213 -11.159 1.00 19.30  ? 377 ARG A CD     1 
ATOM   5868  N NE     . ARG A 1 377 ? -19.717 -12.285 -11.797 1.00 17.99  ? 377 ARG A NE     1 
ATOM   5869  C CZ     . ARG A 1 377 ? -19.474 -11.062 -11.336 1.00 20.54  ? 377 ARG A CZ     1 
ATOM   5870  N NH1    . ARG A 1 377 ? -20.099 -10.628 -10.245 1.00 19.50  ? 377 ARG A NH1    1 
ATOM   5871  N NH2    . ARG A 1 377 ? -18.621 -10.269 -11.972 1.00 18.22  ? 377 ARG A NH2    1 
ATOM   5872  H H      . ARG A 1 377 ? -18.052 -17.336 -12.613 1.00 18.17  ? 377 ARG A H      1 
ATOM   5873  H HA     . ARG A 1 377 ? -20.373 -17.187 -11.220 1.00 21.42  ? 377 ARG A HA     1 
ATOM   5874  H HB2    . ARG A 1 377 ? -19.152 -15.297 -10.909 1.00 19.53  ? 377 ARG A HB2    1 
ATOM   5875  H HB3    . ARG A 1 377 ? -18.908 -15.133 -12.472 1.00 19.53  ? 377 ARG A HB3    1 
ATOM   5876  H HG2    . ARG A 1 377 ? -20.943 -14.323 -12.825 1.00 18.34  ? 377 ARG A HG2    1 
ATOM   5877  H HG3    . ARG A 1 377 ? -21.534 -14.996 -11.515 1.00 18.34  ? 377 ARG A HG3    1 
ATOM   5878  H HD2    . ARG A 1 377 ? -21.512 -12.786 -11.121 1.00 23.15  ? 377 ARG A HD2    1 
ATOM   5879  H HD3    . ARG A 1 377 ? -20.319 -13.386 -10.261 1.00 23.15  ? 377 ARG A HD3    1 
ATOM   5880  H HE     . ARG A 1 377 ? -19.418 -12.488 -12.578 1.00 21.58  ? 377 ARG A HE     1 
ATOM   5881  H HH11   . ARG A 1 377 ? -20.654 -11.137 -9.830  1.00 23.40  ? 377 ARG A HH11   1 
ATOM   5882  H HH12   . ARG A 1 377 ? -19.942 -9.836  -9.949  1.00 23.40  ? 377 ARG A HH12   1 
ATOM   5883  H HH21   . ARG A 1 377 ? -18.218 -10.549 -12.679 1.00 21.86  ? 377 ARG A HH21   1 
ATOM   5884  H HH22   . ARG A 1 377 ? -18.466 -9.477  -11.674 1.00 21.86  ? 377 ARG A HH22   1 
ATOM   5885  N N      . SER A 1 378 ? -22.070 -17.280 -12.927 1.00 17.69  ? 378 SER A N      1 
ATOM   5886  C CA     . SER A 1 378 ? -23.114 -17.345 -13.950 1.00 16.94  ? 378 SER A CA     1 
ATOM   5887  C C      . SER A 1 378 ? -24.244 -16.399 -13.561 1.00 20.69  ? 378 SER A C      1 
ATOM   5888  O O      . SER A 1 378 ? -24.293 -15.929 -12.421 1.00 24.72  ? 378 SER A O      1 
ATOM   5889  C CB     . SER A 1 378 ? -23.642 -18.773 -14.097 1.00 17.02  ? 378 SER A CB     1 
ATOM   5890  O OG     . SER A 1 378 ? -24.022 -19.294 -12.840 1.00 21.65  ? 378 SER A OG     1 
ATOM   5891  H H      . SER A 1 378 ? -22.367 -17.409 -12.130 1.00 21.23  ? 378 SER A H      1 
ATOM   5892  H HA     . SER A 1 378 ? -22.759 -17.060 -14.806 1.00 20.33  ? 378 SER A HA     1 
ATOM   5893  H HB2    . SER A 1 378 ? -24.413 -18.768 -14.686 1.00 20.42  ? 378 SER A HB2    1 
ATOM   5894  H HB3    . SER A 1 378 ? -22.941 -19.330 -14.469 1.00 20.42  ? 378 SER A HB3    1 
ATOM   5895  H HG     . SER A 1 378 ? -23.357 -19.322 -12.327 1.00 25.98  ? 378 SER A HG     1 
ATOM   5896  N N      . MET A 1 379 ? -25.145 -16.125 -14.499 1.00 19.94  ? 379 MET A N      1 
ATOM   5897  C CA     . MET A 1 379 ? -26.255 -15.206 -14.261 1.00 23.79  ? 379 MET A CA     1 
ATOM   5898  C C      . MET A 1 379 ? -27.585 -15.928 -14.077 1.00 25.07  ? 379 MET A C      1 
ATOM   5899  O O      . MET A 1 379 ? -27.991 -16.731 -14.916 1.00 21.26  ? 379 MET A O      1 
ATOM   5900  C CB     . MET A 1 379 ? -26.407 -14.211 -15.417 1.00 25.70  ? 379 MET A CB     1 
ATOM   5901  C CG     . MET A 1 379 ? -27.387 -13.088 -15.095 1.00 24.49  ? 379 MET A CG     1 
ATOM   5902  S SD     . MET A 1 379 ? -27.623 -11.865 -16.399 1.00 29.16  ? 379 MET A SD     1 
ATOM   5903  C CE     . MET A 1 379 ? -26.063 -10.979 -16.359 1.00 25.06  ? 379 MET A CE     1 
ATOM   5904  H H      . MET A 1 379 ? -25.136 -16.462 -15.290 1.00 23.93  ? 379 MET A H      1 
ATOM   5905  H HA     . MET A 1 379 ? -26.075 -14.688 -13.461 1.00 28.55  ? 379 MET A HA     1 
ATOM   5906  H HB2    . MET A 1 379 ? -25.546 -13.816 -15.620 1.00 30.84  ? 379 MET A HB2    1 
ATOM   5907  H HB3    . MET A 1 379 ? -26.743 -14.684 -16.194 1.00 30.84  ? 379 MET A HB3    1 
ATOM   5908  H HG2    . MET A 1 379 ? -28.253 -13.478 -14.910 1.00 29.39  ? 379 MET A HG2    1 
ATOM   5909  H HG3    . MET A 1 379 ? -27.068 -12.618 -14.309 1.00 29.39  ? 379 MET A HG3    1 
ATOM   5910  H HE1    . MET A 1 379 ? -25.987 -10.438 -17.161 1.00 30.07  ? 379 MET A HE1    1 
ATOM   5911  H HE2    . MET A 1 379 ? -26.040 -10.412 -15.574 1.00 30.07  ? 379 MET A HE2    1 
ATOM   5912  H HE3    . MET A 1 379 ? -25.340 -11.622 -16.323 1.00 30.07  ? 379 MET A HE3    1 
ATOM   5913  N N      . GLU A 1 380 ? -28.264 -15.618 -12.978 1.00 23.20  ? 380 GLU A N      1 
ATOM   5914  C CA     . GLU A 1 380 ? -29.668 -15.975 -12.818 1.00 27.28  ? 380 GLU A CA     1 
ATOM   5915  C C      . GLU A 1 380 ? -30.509 -15.291 -13.896 1.00 22.59  ? 380 GLU A C      1 
ATOM   5916  O O      . GLU A 1 380 ? -30.486 -14.070 -14.033 1.00 23.56  ? 380 GLU A O      1 
ATOM   5917  C CB     . GLU A 1 380 ? -30.169 -15.573 -11.424 1.00 29.48  ? 380 GLU A CB     1 
ATOM   5918  C CG     . GLU A 1 380 ? -31.444 -16.299 -10.952 1.00 31.48  ? 380 GLU A CG     1 
ATOM   5919  C CD     . GLU A 1 380 ? -32.750 -15.653 -11.420 1.00 31.88  ? 380 GLU A CD     1 
ATOM   5920  O OE1    . GLU A 1 380 ? -32.722 -14.609 -12.108 1.00 32.99  ? 380 GLU A OE1    1 
ATOM   5921  O OE2    . GLU A 1 380 ? -33.824 -16.199 -11.082 1.00 34.54  ? 380 GLU A OE2    1 
ATOM   5922  H H      . GLU A 1 380 ? -27.931 -15.198 -12.305 1.00 27.83  ? 380 GLU A H      1 
ATOM   5923  H HA     . GLU A 1 380 ? -29.769 -16.935 -12.915 1.00 32.73  ? 380 GLU A HA     1 
ATOM   5924  H HB2    . GLU A 1 380 ? -29.470 -15.770 -10.781 1.00 35.37  ? 380 GLU A HB2    1 
ATOM   5925  H HB3    . GLU A 1 380 ? -30.348 -14.620 -11.421 1.00 35.37  ? 380 GLU A HB3    1 
ATOM   5926  H HG2    . GLU A 1 380 ? -31.427 -17.208 -11.290 1.00 37.77  ? 380 GLU A HG2    1 
ATOM   5927  H HG3    . GLU A 1 380 ? -31.453 -16.312 -9.982  1.00 37.77  ? 380 GLU A HG3    1 
ATOM   5928  N N      . ARG A 1 381 ? -31.243 -16.082 -14.668 1.00 27.46  ? 381 ARG A N      1 
ATOM   5929  C CA     . ARG A 1 381 ? -32.206 -15.546 -15.625 1.00 27.64  ? 381 ARG A CA     1 
ATOM   5930  C C      . ARG A 1 381 ? -33.505 -16.313 -15.413 1.00 35.18  ? 381 ARG A C      1 
ATOM   5931  O O      . ARG A 1 381 ? -33.874 -17.182 -16.210 1.00 31.08  ? 381 ARG A O      1 
ATOM   5932  C CB     . ARG A 1 381 ? -31.701 -15.670 -17.071 1.00 25.17  ? 381 ARG A CB     1 
ATOM   5933  C CG     . ARG A 1 381 ? -30.441 -14.847 -17.380 1.00 26.74  ? 381 ARG A CG     1 
ATOM   5934  C CD     . ARG A 1 381 ? -30.738 -13.351 -17.621 1.00 26.25  ? 381 ARG A CD     1 
ATOM   5935  N NE     . ARG A 1 381 ? -30.829 -12.572 -16.385 1.00 30.39  ? 381 ARG A NE     1 
ATOM   5936  C CZ     . ARG A 1 381 ? -30.968 -11.247 -16.334 1.00 32.18  ? 381 ARG A CZ     1 
ATOM   5937  N NH1    . ARG A 1 381 ? -31.030 -10.528 -17.451 1.00 37.02  ? 381 ARG A NH1    1 
ATOM   5938  N NH2    . ARG A 1 381 ? -31.040 -10.632 -15.159 1.00 34.61  ? 381 ARG A NH2    1 
ATOM   5939  H H      . ARG A 1 381 ? -31.203 -16.941 -14.658 1.00 32.95  ? 381 ARG A H      1 
ATOM   5940  H HA     . ARG A 1 381 ? -32.376 -14.610 -15.440 1.00 33.17  ? 381 ARG A HA     1 
ATOM   5941  H HB2    . ARG A 1 381 ? -31.494 -16.601 -17.248 1.00 30.20  ? 381 ARG A HB2    1 
ATOM   5942  H HB3    . ARG A 1 381 ? -32.403 -15.372 -17.671 1.00 30.20  ? 381 ARG A HB3    1 
ATOM   5943  H HG2    . ARG A 1 381 ? -29.830 -14.913 -16.630 1.00 32.08  ? 381 ARG A HG2    1 
ATOM   5944  H HG3    . ARG A 1 381 ? -30.022 -15.201 -18.180 1.00 32.08  ? 381 ARG A HG3    1 
ATOM   5945  H HD2    . ARG A 1 381 ? -30.026 -12.973 -18.160 1.00 31.50  ? 381 ARG A HD2    1 
ATOM   5946  H HD3    . ARG A 1 381 ? -31.584 -13.269 -18.088 1.00 31.50  ? 381 ARG A HD3    1 
ATOM   5947  H HE     . ARG A 1 381 ? -30.790 -12.999 -15.639 1.00 36.46  ? 381 ARG A HE     1 
ATOM   5948  H HH11   . ARG A 1 381 ? -30.984 -10.915 -18.218 1.00 44.42  ? 381 ARG A HH11   1 
ATOM   5949  H HH12   . ARG A 1 381 ? -31.119 -9.674  -17.406 1.00 44.42  ? 381 ARG A HH12   1 
ATOM   5950  H HH21   . ARG A 1 381 ? -31.000 -11.089 -14.431 1.00 41.53  ? 381 ARG A HH21   1 
ATOM   5951  H HH22   . ARG A 1 381 ? -31.129 -9.777  -15.126 1.00 41.53  ? 381 ARG A HH22   1 
ATOM   5952  N N      . GLY A 1 382 ? -34.173 -15.996 -14.304 1.00 34.84  ? 382 GLY A N      1 
ATOM   5953  C CA     . GLY A 1 382 ? -35.378 -16.692 -13.889 1.00 36.61  ? 382 GLY A CA     1 
ATOM   5954  C C      . GLY A 1 382 ? -36.297 -15.804 -13.065 1.00 35.21  ? 382 GLY A C      1 
ATOM   5955  O O      . GLY A 1 382 ? -36.420 -14.605 -13.330 1.00 35.54  ? 382 GLY A O      1 
ATOM   5956  H H      . GLY A 1 382 ? -33.938 -15.366 -13.768 1.00 41.80  ? 382 GLY A H      1 
ATOM   5957  H HA2    . GLY A 1 382 ? -35.866 -16.995 -14.670 1.00 43.93  ? 382 GLY A HA2    1 
ATOM   5958  H HA3    . GLY A 1 382 ? -35.138 -17.466 -13.356 1.00 43.93  ? 382 GLY A HA3    1 
ATOM   5959  N N      . ILE A 1 383 ? -36.926 -16.392 -12.051 1.00 35.13  ? 383 ILE A N      1 
ATOM   5960  C CA     . ILE A 1 383 ? -37.965 -15.708 -11.283 1.00 38.31  ? 383 ILE A CA     1 
ATOM   5961  C C      . ILE A 1 383 ? -37.451 -14.433 -10.594 1.00 36.73  ? 383 ILE A C      1 
ATOM   5962  O O      . ILE A 1 383 ? -38.155 -13.424 -10.558 1.00 35.56  ? 383 ILE A O      1 
ATOM   5963  C CB     . ILE A 1 383 ? -38.590 -16.664 -10.228 1.00 36.84  ? 383 ILE A CB     1 
ATOM   5964  C CG1    . ILE A 1 383 ? -39.752 -15.981 -9.502  1.00 43.98  ? 383 ILE A CG1    1 
ATOM   5965  C CG2    . ILE A 1 383 ? -37.544 -17.164 -9.243  1.00 37.09  ? 383 ILE A CG2    1 
ATOM   5966  C CD1    . ILE A 1 383 ? -40.632 -16.947 -8.710  1.00 40.66  ? 383 ILE A CD1    1 
ATOM   5967  H H      . ILE A 1 383 ? -36.769 -17.195 -11.787 1.00 42.16  ? 383 ILE A H      1 
ATOM   5968  H HA     . ILE A 1 383 ? -38.672 -15.444 -11.892 1.00 45.97  ? 383 ILE A HA     1 
ATOM   5969  H HB     . ILE A 1 383 ? -38.946 -17.434 -10.699 1.00 44.21  ? 383 ILE A HB     1 
ATOM   5970  H HG12   . ILE A 1 383 ? -39.394 -15.329 -8.879  1.00 52.77  ? 383 ILE A HG12   1 
ATOM   5971  H HG13   . ILE A 1 383 ? -40.312 -15.537 -10.157 1.00 52.77  ? 383 ILE A HG13   1 
ATOM   5972  H HG21   . ILE A 1 383 ? -37.940 -17.854 -8.687  1.00 44.51  ? 383 ILE A HG21   1 
ATOM   5973  H HG22   . ILE A 1 383 ? -36.792 -17.529 -9.734  1.00 44.51  ? 383 ILE A HG22   1 
ATOM   5974  H HG23   . ILE A 1 383 ? -37.250 -16.424 -8.690  1.00 44.51  ? 383 ILE A HG23   1 
ATOM   5975  H HD11   . ILE A 1 383 ? -41.354 -16.450 -8.296  1.00 48.79  ? 383 ILE A HD11   1 
ATOM   5976  H HD12   . ILE A 1 383 ? -40.993 -17.613 -9.316  1.00 48.79  ? 383 ILE A HD12   1 
ATOM   5977  H HD13   . ILE A 1 383 ? -40.094 -17.378 -8.028  1.00 48.79  ? 383 ILE A HD13   1 
ATOM   5978  N N      . ILE A 1 384 ? -36.230 -14.466 -10.071 1.00 31.65  ? 384 ILE A N      1 
ATOM   5979  C CA     . ILE A 1 384 ? -35.659 -13.277 -9.437  1.00 35.08  ? 384 ILE A CA     1 
ATOM   5980  C C      . ILE A 1 384 ? -35.514 -12.133 -10.438 1.00 33.72  ? 384 ILE A C      1 
ATOM   5981  O O      . ILE A 1 384 ? -35.969 -11.017 -10.178 1.00 30.44  ? 384 ILE A O      1 
ATOM   5982  C CB     . ILE A 1 384 ? -34.281 -13.574 -8.795  1.00 38.11  ? 384 ILE A CB     1 
ATOM   5983  C CG1    . ILE A 1 384 ? -34.401 -14.682 -7.745  1.00 35.41  ? 384 ILE A CG1    1 
ATOM   5984  C CG2    . ILE A 1 384 ? -33.695 -12.313 -8.149  1.00 32.95  ? 384 ILE A CG2    1 
ATOM   5985  C CD1    . ILE A 1 384 ? -35.345 -14.352 -6.584  1.00 35.39  ? 384 ILE A CD1    1 
ATOM   5986  H H      . ILE A 1 384 ? -35.715 -15.155 -10.069 1.00 37.98  ? 384 ILE A H      1 
ATOM   5987  H HA     . ILE A 1 384 ? -36.258 -12.979 -8.735  1.00 42.09  ? 384 ILE A HA     1 
ATOM   5988  H HB     . ILE A 1 384 ? -33.675 -13.873 -9.491  1.00 45.73  ? 384 ILE A HB     1 
ATOM   5989  H HG12   . ILE A 1 384 ? -34.733 -15.485 -8.175  1.00 42.49  ? 384 ILE A HG12   1 
ATOM   5990  H HG13   . ILE A 1 384 ? -33.523 -14.852 -7.370  1.00 42.49  ? 384 ILE A HG13   1 
ATOM   5991  H HG21   . ILE A 1 384 ? -32.994 -12.573 -7.531  1.00 39.53  ? 384 ILE A HG21   1 
ATOM   5992  H HG22   . ILE A 1 384 ? -33.329 -11.742 -8.842  1.00 39.53  ? 384 ILE A HG22   1 
ATOM   5993  H HG23   . ILE A 1 384 ? -34.399 -11.846 -7.672  1.00 39.53  ? 384 ILE A HG23   1 
ATOM   5994  H HD11   . ILE A 1 384 ? -35.212 -15.001 -5.877  1.00 42.47  ? 384 ILE A HD11   1 
ATOM   5995  H HD12   . ILE A 1 384 ? -35.148 -13.463 -6.251  1.00 42.47  ? 384 ILE A HD12   1 
ATOM   5996  H HD13   . ILE A 1 384 ? -36.261 -14.390 -6.901  1.00 42.47  ? 384 ILE A HD13   1 
ATOM   5997  N N      . SER A 1 385 ? -34.888 -12.406 -11.582 1.00 30.94  ? 385 SER A N      1 
ATOM   5998  C CA     . SER A 1 385 ? -34.710 -11.387 -12.616 1.00 31.98  ? 385 SER A CA     1 
ATOM   5999  C C      . SER A 1 385 ? -36.035 -10.922 -13.205 1.00 34.92  ? 385 SER A C      1 
ATOM   6000  O O      . SER A 1 385 ? -36.125 -9.816  -13.740 1.00 31.59  ? 385 SER A O      1 
ATOM   6001  C CB     . SER A 1 385 ? -33.809 -11.911 -13.739 1.00 30.65  ? 385 SER A CB     1 
ATOM   6002  O OG     . SER A 1 385 ? -32.476 -12.061 -13.279 1.00 30.90  ? 385 SER A OG     1 
ATOM   6003  H H      . SER A 1 385 ? -34.557 -13.174 -11.784 1.00 37.12  ? 385 SER A H      1 
ATOM   6004  H HA     . SER A 1 385 ? -34.276 -10.615 -12.223 1.00 38.38  ? 385 SER A HA     1 
ATOM   6005  H HB2    . SER A 1 385 ? -34.141 -12.773 -14.035 1.00 36.78  ? 385 SER A HB2    1 
ATOM   6006  H HB3    . SER A 1 385 ? -33.821 -11.279 -14.475 1.00 36.78  ? 385 SER A HB3    1 
ATOM   6007  H HG     . SER A 1 385 ? -32.452 -12.605 -12.640 1.00 37.08  ? 385 SER A HG     1 
ATOM   6008  N N      . ALA A 1 386 ? -37.060 -11.763 -13.109 1.00 34.82  ? 386 ALA A N      1 
ATOM   6009  C CA     . ALA A 1 386 ? -38.376 -11.428 -13.657 1.00 40.56  ? 386 ALA A CA     1 
ATOM   6010  C C      . ALA A 1 386 ? -39.026 -10.277 -12.888 1.00 40.43  ? 386 ALA A C      1 
ATOM   6011  O O      . ALA A 1 386 ? -39.842 -9.532  -13.437 1.00 41.06  ? 386 ALA A O      1 
ATOM   6012  C CB     . ALA A 1 386 ? -39.285 -12.651 -13.638 1.00 38.51  ? 386 ALA A CB     1 
ATOM   6013  H H      . ALA A 1 386 ? -37.023 -12.535 -12.732 1.00 41.78  ? 386 ALA A H      1 
ATOM   6014  H HA     . ALA A 1 386 ? -38.271 -11.149 -14.580 1.00 48.67  ? 386 ALA A HA     1 
ATOM   6015  H HB1    . ALA A 1 386 ? -40.141 -12.413 -14.028 1.00 46.22  ? 386 ALA A HB1    1 
ATOM   6016  H HB2    . ALA A 1 386 ? -38.871 -13.359 -14.155 1.00 46.22  ? 386 ALA A HB2    1 
ATOM   6017  H HB3    . ALA A 1 386 ? -39.408 -12.940 -12.721 1.00 46.22  ? 386 ALA A HB3    1 
ATOM   6018  N N      . GLY A 1 387 ? -38.664 -10.140 -11.617 1.00 41.69  ? 387 GLY A N      1 
ATOM   6019  C CA     . GLY A 1 387 ? -39.184 -9.071  -10.786 1.00 48.56  ? 387 GLY A CA     1 
ATOM   6020  C C      . GLY A 1 387 ? -40.498 -9.459  -10.137 1.00 57.41  ? 387 GLY A C      1 
ATOM   6021  O O      . GLY A 1 387 ? -41.042 -10.533 -10.404 1.00 49.54  ? 387 GLY A O      1 
ATOM   6022  H H      . GLY A 1 387 ? -38.113 -10.661 -11.211 1.00 50.02  ? 387 GLY A H      1 
ATOM   6023  H HA2    . GLY A 1 387 ? -38.544 -8.864  -10.087 1.00 58.27  ? 387 GLY A HA2    1 
ATOM   6024  H HA3    . GLY A 1 387 ? -39.324 -8.275  -11.322 1.00 58.27  ? 387 GLY A HA3    1 
ATOM   6025  N N      . ARG A 1 388 ? -41.005 -8.581  -9.277  1.00 53.81  ? 388 ARG A N      1 
ATOM   6026  C CA     . ARG A 1 388 ? -42.254 -8.835  -8.574  1.00 61.11  ? 388 ARG A CA     1 
ATOM   6027  C C      . ARG A 1 388 ? -43.416 -8.189  -9.323  1.00 62.60  ? 388 ARG A C      1 
ATOM   6028  O O      . ARG A 1 388 ? -43.274 -7.100  -9.881  1.00 60.07  ? 388 ARG A O      1 
ATOM   6029  C CB     . ARG A 1 388 ? -42.174 -8.312  -7.140  1.00 55.03  ? 388 ARG A CB     1 
ATOM   6030  C CG     . ARG A 1 388 ? -43.265 -8.843  -6.233  1.00 56.18  ? 388 ARG A CG     1 
ATOM   6031  C CD     . ARG A 1 388 ? -42.989 -8.505  -4.783  1.00 53.81  ? 388 ARG A CD     1 
ATOM   6032  N NE     . ARG A 1 388 ? -41.906 -9.302  -4.209  1.00 46.00  ? 388 ARG A NE     1 
ATOM   6033  C CZ     . ARG A 1 388 ? -42.053 -10.524 -3.700  1.00 48.78  ? 388 ARG A CZ     1 
ATOM   6034  N NH1    . ARG A 1 388 ? -43.240 -11.118 -3.699  1.00 51.31  ? 388 ARG A NH1    1 
ATOM   6035  N NH2    . ARG A 1 388 ? -41.006 -11.160 -3.193  1.00 46.87  ? 388 ARG A NH2    1 
ATOM   6036  H H      . ARG A 1 388 ? -40.641 -7.826  -9.083  1.00 64.57  ? 388 ARG A H      1 
ATOM   6037  H HA     . ARG A 1 388 ? -42.417 -9.790  -8.532  1.00 73.34  ? 388 ARG A HA     1 
ATOM   6038  H HB2    . ARG A 1 388 ? -41.320 -8.572  -6.760  1.00 66.04  ? 388 ARG A HB2    1 
ATOM   6039  H HB3    . ARG A 1 388 ? -42.246 -7.345  -7.156  1.00 66.04  ? 388 ARG A HB3    1 
ATOM   6040  H HG2    . ARG A 1 388 ? -44.113 -8.443  -6.483  1.00 67.41  ? 388 ARG A HG2    1 
ATOM   6041  H HG3    . ARG A 1 388 ? -43.311 -9.808  -6.317  1.00 67.41  ? 388 ARG A HG3    1 
ATOM   6042  H HD2    . ARG A 1 388 ? -42.731 -7.572  -4.725  1.00 64.57  ? 388 ARG A HD2    1 
ATOM   6043  H HD3    . ARG A 1 388 ? -43.789 -8.656  -4.258  1.00 64.57  ? 388 ARG A HD3    1 
ATOM   6044  H HE     . ARG A 1 388 ? -41.118 -8.957  -4.199  1.00 55.21  ? 388 ARG A HE     1 
ATOM   6045  H HH11   . ARG A 1 388 ? -43.927 -10.716 -4.023  1.00 61.57  ? 388 ARG A HH11   1 
ATOM   6046  H HH12   . ARG A 1 388 ? -43.323 -11.908 -3.370  1.00 61.57  ? 388 ARG A HH12   1 
ATOM   6047  H HH21   . ARG A 1 388 ? -40.233 -10.783 -3.193  1.00 56.25  ? 388 ARG A HH21   1 
ATOM   6048  H HH22   . ARG A 1 388 ? -41.099 -11.951 -2.869  1.00 56.25  ? 388 ARG A HH22   1 
ATOM   6049  N N      . ASN A 1 389 ? -44.555 -8.876  -9.350  1.00 70.87  ? 389 ASN A N      1 
ATOM   6050  C CA     . ASN A 1 389 ? -45.750 -8.363  -10.014 1.00 79.37  ? 389 ASN A CA     1 
ATOM   6051  C C      . ASN A 1 389 ? -46.267 -7.121  -9.301  1.00 81.41  ? 389 ASN A C      1 
ATOM   6052  O O      . ASN A 1 389 ? -46.696 -7.181  -8.148  1.00 72.91  ? 389 ASN A O      1 
ATOM   6053  C CB     . ASN A 1 389 ? -46.841 -9.437  -10.073 1.00 86.12  ? 389 ASN A CB     1 
ATOM   6054  C CG     . ASN A 1 389 ? -47.916 -9.128  -11.100 1.00 83.15  ? 389 ASN A CG     1 
ATOM   6055  O OD1    . ASN A 1 389 ? -48.196 -7.964  -11.398 1.00 74.59  ? 389 ASN A OD1    1 
ATOM   6056  N ND2    . ASN A 1 389 ? -48.534 -10.175 -11.641 1.00 82.15  ? 389 ASN A ND2    1 
ATOM   6057  H H      . ASN A 1 389 ? -44.660 -9.649  -8.992  1.00 85.04  ? 389 ASN A H      1 
ATOM   6058  H HA     . ASN A 1 389 ? -45.526 -8.113  -10.923 1.00 95.24  ? 389 ASN A HA     1 
ATOM   6059  H HB2    . ASN A 1 389 ? -46.436 -10.286 -10.310 1.00 103.34 ? 389 ASN A HB2    1 
ATOM   6060  H HB3    . ASN A 1 389 ? -47.263 -9.502  -9.204  1.00 103.34 ? 389 ASN A HB3    1 
ATOM   6061  H HD21   . ASN A 1 389 ? -49.151 -10.054 -12.228 1.00 98.58  ? 389 ASN A HD21   1 
ATOM   6062  H HD22   . ASN A 1 389 ? -48.317 -10.972 -11.404 1.00 98.58  ? 389 ASN A HD22   1 
ATOM   6063  N N      . LYS A 1 390 ? -46.222 -5.998  -10.008 1.00 88.84  ? 390 LYS A N      1 
ATOM   6064  C CA     . LYS A 1 390 ? -46.532 -4.696  -9.430  1.00 93.09  ? 390 LYS A CA     1 
ATOM   6065  C C      . LYS A 1 390 ? -47.948 -4.640  -8.862  1.00 97.21  ? 390 LYS A C      1 
ATOM   6066  O O      . LYS A 1 390 ? -48.170 -4.125  -7.765  1.00 81.06  ? 390 LYS A O      1 
ATOM   6067  C CB     . LYS A 1 390 ? -46.360 -3.602  -10.486 1.00 89.52  ? 390 LYS A CB     1 
ATOM   6068  C CG     . LYS A 1 390 ? -45.023 -3.634  -11.214 1.00 85.77  ? 390 LYS A CG     1 
ATOM   6069  C CD     . LYS A 1 390 ? -45.002 -2.634  -12.352 1.00 83.61  ? 390 LYS A CD     1 
ATOM   6070  C CE     . LYS A 1 390 ? -43.642 -2.588  -13.022 1.00 84.13  ? 390 LYS A CE     1 
ATOM   6071  N NZ     . LYS A 1 390 ? -43.598 -1.562  -14.096 1.00 90.96  ? 390 LYS A NZ     1 
ATOM   6072  H H      . LYS A 1 390 ? -46.018 -5.968  -10.842 1.00 106.61 ? 390 LYS A H      1 
ATOM   6073  H HA     . LYS A 1 390 ? -45.911 -4.516  -8.707  1.00 111.71 ? 390 LYS A HA     1 
ATOM   6074  H HB2    . LYS A 1 390 ? -47.060 -3.700  -11.151 1.00 107.43 ? 390 LYS A HB2    1 
ATOM   6075  H HB3    . LYS A 1 390 ? -46.439 -2.738  -10.053 1.00 107.43 ? 390 LYS A HB3    1 
ATOM   6076  H HG2    . LYS A 1 390 ? -44.314 -3.404  -10.593 1.00 102.93 ? 390 LYS A HG2    1 
ATOM   6077  H HG3    . LYS A 1 390 ? -44.871 -4.515  -11.588 1.00 102.93 ? 390 LYS A HG3    1 
ATOM   6078  H HD2    . LYS A 1 390 ? -45.660 -2.891  -13.017 1.00 100.33 ? 390 LYS A HD2    1 
ATOM   6079  H HD3    . LYS A 1 390 ? -45.201 -1.750  -12.006 1.00 100.33 ? 390 LYS A HD3    1 
ATOM   6080  H HE2    . LYS A 1 390 ? -42.967 -2.366  -12.362 1.00 100.95 ? 390 LYS A HE2    1 
ATOM   6081  H HE3    . LYS A 1 390 ? -43.451 -3.452  -13.419 1.00 100.95 ? 390 LYS A HE3    1 
ATOM   6082  H HZ1    . LYS A 1 390 ? -42.793 -1.553  -14.475 1.00 109.16 ? 390 LYS A HZ1    1 
ATOM   6083  H HZ2    . LYS A 1 390 ? -44.208 -1.746  -14.718 1.00 109.16 ? 390 LYS A HZ2    1 
ATOM   6084  H HZ3    . LYS A 1 390 ? -43.767 -0.757  -13.755 1.00 109.16 ? 390 LYS A HZ3    1 
ATOM   6085  N N      . GLU A 1 391 ? -48.898 -5.182  -9.617  1.00 102.43 ? 391 GLU A N      1 
ATOM   6086  C CA     . GLU A 1 391 ? -50.311 -5.054  -9.286  1.00 97.64  ? 391 GLU A CA     1 
ATOM   6087  C C      . GLU A 1 391 ? -50.722 -5.965  -8.125  1.00 96.71  ? 391 GLU A C      1 
ATOM   6088  O O      . GLU A 1 391 ? -51.349 -5.507  -7.169  1.00 92.82  ? 391 GLU A O      1 
ATOM   6089  C CB     . GLU A 1 391 ? -51.158 -5.352  -10.529 1.00 89.15  ? 391 GLU A CB     1 
ATOM   6090  C CG     . GLU A 1 391 ? -52.648 -5.038  -10.379 1.00 93.87  ? 391 GLU A CG     1 
ATOM   6091  C CD     . GLU A 1 391 ? -53.494 -6.236  -9.964  1.00 110.64 ? 391 GLU A CD     1 
ATOM   6092  O OE1    . GLU A 1 391 ? -53.056 -7.392  -10.151 1.00 107.39 ? 391 GLU A OE1    1 
ATOM   6093  O OE2    . GLU A 1 391 ? -54.613 -6.011  -9.454  1.00 105.33 ? 391 GLU A OE2    1 
ATOM   6094  H H      . GLU A 1 391 ? -48.747 -5.633  -10.333 1.00 122.91 ? 391 GLU A H      1 
ATOM   6095  H HA     . GLU A 1 391 ? -50.488 -4.138  -9.020  1.00 117.17 ? 391 GLU A HA     1 
ATOM   6096  H HB2    . GLU A 1 391 ? -50.824 -4.808  -11.259 1.00 106.98 ? 391 GLU A HB2    1 
ATOM   6097  H HB3    . GLU A 1 391 ? -51.056 -6.288  -10.758 1.00 106.98 ? 391 GLU A HB3    1 
ATOM   6098  H HG2    . GLU A 1 391 ? -52.756 -4.351  -9.703  1.00 112.64 ? 391 GLU A HG2    1 
ATOM   6099  H HG3    . GLU A 1 391 ? -52.986 -4.717  -11.230 1.00 112.64 ? 391 GLU A HG3    1 
ATOM   6100  N N      . THR A 1 392 ? -50.351 -7.242  -8.199  1.00 94.46  ? 392 THR A N      1 
ATOM   6101  C CA     . THR A 1 392 ? -50.796 -8.233  -7.215  1.00 87.94  ? 392 THR A CA     1 
ATOM   6102  C C      . THR A 1 392 ? -49.758 -8.498  -6.121  1.00 85.68  ? 392 THR A C      1 
ATOM   6103  O O      . THR A 1 392 ? -50.065 -9.133  -5.110  1.00 86.08  ? 392 THR A O      1 
ATOM   6104  C CB     . THR A 1 392 ? -51.156 -9.581  -7.890  1.00 86.21  ? 392 THR A CB     1 
ATOM   6105  O OG1    . THR A 1 392 ? -51.375 -10.577 -6.883  1.00 100.04 ? 392 THR A OG1    1 
ATOM   6106  C CG2    . THR A 1 392 ? -50.051 -10.049 -8.817  1.00 78.18  ? 392 THR A CG2    1 
ATOM   6107  H H      . THR A 1 392 ? -49.837 -7.559  -8.810  1.00 113.35 ? 392 THR A H      1 
ATOM   6108  H HA     . THR A 1 392 ? -51.599 -7.907  -6.781  1.00 105.53 ? 392 THR A HA     1 
ATOM   6109  H HB     . THR A 1 392 ? -51.966 -9.471  -8.413  1.00 103.46 ? 392 THR A HB     1 
ATOM   6110  H HG1    . THR A 1 392 ? -52.006 -10.343 -6.380  1.00 120.05 ? 392 THR A HG1    1 
ATOM   6111  H HG21   . THR A 1 392 ? -50.216 -10.964 -9.093  1.00 93.82  ? 392 THR A HG21   1 
ATOM   6112  H HG22   . THR A 1 392 ? -50.026 -9.484  -9.603  1.00 93.82  ? 392 THR A HG22   1 
ATOM   6113  H HG23   . THR A 1 392 ? -49.197 -10.007 -8.361  1.00 93.82  ? 392 THR A HG23   1 
ATOM   6114  N N      . GLY A 1 393 ? -48.535 -8.019  -6.324  1.00 78.40  ? 393 GLY A N      1 
ATOM   6115  C CA     . GLY A 1 393 ? -47.498 -8.135  -5.313  1.00 72.93  ? 393 GLY A CA     1 
ATOM   6116  C C      . GLY A 1 393 ? -46.849 -9.506  -5.224  1.00 75.55  ? 393 GLY A C      1 
ATOM   6117  O O      . GLY A 1 393 ? -46.000 -9.734  -4.364  1.00 68.12  ? 393 GLY A O      1 
ATOM   6118  H H      . GLY A 1 393 ? -48.280 -7.622  -7.043  1.00 94.08  ? 393 GLY A H      1 
ATOM   6119  H HA2    . GLY A 1 393 ? -46.802 -7.486  -5.501  1.00 87.51  ? 393 GLY A HA2    1 
ATOM   6120  H HA3    . GLY A 1 393 ? -47.877 -7.926  -4.445  1.00 87.51  ? 393 GLY A HA3    1 
ATOM   6121  N N      . ASP A 1 394 ? -47.249 -10.423 -6.100  1.00 70.30  ? 394 ASP A N      1 
ATOM   6122  C CA     . ASP A 1 394 ? -46.632 -11.747 -6.161  1.00 70.08  ? 394 ASP A CA     1 
ATOM   6123  C C      . ASP A 1 394 ? -45.495 -11.722 -7.182  1.00 67.34  ? 394 ASP A C      1 
ATOM   6124  O O      . ASP A 1 394 ? -45.383 -10.776 -7.962  1.00 55.54  ? 394 ASP A O      1 
ATOM   6125  C CB     . ASP A 1 394 ? -47.673 -12.812 -6.525  1.00 66.90  ? 394 ASP A CB     1 
ATOM   6126  C CG     . ASP A 1 394 ? -47.111 -14.227 -6.475  1.00 76.56  ? 394 ASP A CG     1 
ATOM   6127  O OD1    . ASP A 1 394 ? -46.385 -14.552 -5.512  1.00 70.85  ? 394 ASP A OD1    1 
ATOM   6128  O OD2    . ASP A 1 394 ? -47.393 -15.014 -7.406  1.00 71.50  ? 394 ASP A OD2    1 
ATOM   6129  H H      . ASP A 1 394 ? -47.879 -10.305 -6.673  1.00 84.36  ? 394 ASP A H      1 
ATOM   6130  H HA     . ASP A 1 394 ? -46.259 -11.976 -5.296  1.00 84.09  ? 394 ASP A HA     1 
ATOM   6131  H HB2    . ASP A 1 394 ? -48.411 -12.760 -5.898  1.00 80.28  ? 394 ASP A HB2    1 
ATOM   6132  H HB3    . ASP A 1 394 ? -47.991 -12.647 -7.426  1.00 80.28  ? 394 ASP A HB3    1 
ATOM   6133  N N      . HIS A 1 395 ? -44.641 -12.743 -7.167  1.00 64.75  ? 395 HIS A N      1 
ATOM   6134  C CA     . HIS A 1 395 ? -43.600 -12.870 -8.181  1.00 55.63  ? 395 HIS A CA     1 
ATOM   6135  C C      . HIS A 1 395 ? -44.214 -12.921 -9.579  1.00 53.34  ? 395 HIS A C      1 
ATOM   6136  O O      . HIS A 1 395 ? -45.284 -13.498 -9.764  1.00 57.22  ? 395 HIS A O      1 
ATOM   6137  C CB     . HIS A 1 395 ? -42.771 -14.141 -7.976  1.00 47.80  ? 395 HIS A CB     1 
ATOM   6138  C CG     . HIS A 1 395 ? -42.120 -14.252 -6.635  1.00 47.01  ? 395 HIS A CG     1 
ATOM   6139  N ND1    . HIS A 1 395 ? -41.250 -13.304 -6.144  1.00 47.34  ? 395 HIS A ND1    1 
ATOM   6140  C CD2    . HIS A 1 395 ? -42.180 -15.229 -5.698  1.00 49.13  ? 395 HIS A CD2    1 
ATOM   6141  C CE1    . HIS A 1 395 ? -40.820 -13.679 -4.952  1.00 49.14  ? 395 HIS A CE1    1 
ATOM   6142  N NE2    . HIS A 1 395 ? -41.368 -14.844 -4.659  1.00 50.56  ? 395 HIS A NE2    1 
ATOM   6143  H H      . HIS A 1 395 ? -44.643 -13.373 -6.582  1.00 77.70  ? 395 HIS A H      1 
ATOM   6144  H HA     . HIS A 1 395 ? -43.006 -12.104 -8.133  1.00 66.76  ? 395 HIS A HA     1 
ATOM   6145  H HB2    . HIS A 1 395 ? -43.352 -14.910 -8.085  1.00 57.36  ? 395 HIS A HB2    1 
ATOM   6146  H HB3    . HIS A 1 395 ? -42.070 -14.164 -8.646  1.00 57.36  ? 395 HIS A HB3    1 
ATOM   6147  H HD1    . HIS A 1 395 ? -41.031 -12.577 -6.546  1.00 56.81  ? 395 HIS A HD1    1 
ATOM   6148  H HD2    . HIS A 1 395 ? -42.685 -16.009 -5.745  1.00 58.95  ? 395 HIS A HD2    1 
ATOM   6149  H HE1    . HIS A 1 395 ? -40.230 -13.204 -4.412  1.00 58.97  ? 395 HIS A HE1    1 
ATOM   6150  N N      . HIS A 1 396 ? -43.543 -12.322 -10.558 1.00 56.24  ? 396 HIS A N      1 
ATOM   6151  C CA     . HIS A 1 396 ? -43.740 -12.732 -11.946 1.00 54.35  ? 396 HIS A CA     1 
ATOM   6152  C C      . HIS A 1 396 ? -43.147 -14.126 -12.068 1.00 52.93  ? 396 HIS A C      1 
ATOM   6153  O O      . HIS A 1 396 ? -42.057 -14.373 -11.548 1.00 55.18  ? 396 HIS A O      1 
ATOM   6154  C CB     . HIS A 1 396 ? -43.062 -11.787 -12.937 1.00 52.59  ? 396 HIS A CB     1 
ATOM   6155  C CG     . HIS A 1 396 ? -43.739 -10.461 -13.079 1.00 61.16  ? 396 HIS A CG     1 
ATOM   6156  N ND1    . HIS A 1 396 ? -45.011 -10.324 -13.593 1.00 67.62  ? 396 HIS A ND1    1 
ATOM   6157  C CD2    . HIS A 1 396 ? -43.314 -9.208  -12.792 1.00 61.52  ? 396 HIS A CD2    1 
ATOM   6158  C CE1    . HIS A 1 396 ? -45.344 -9.046  -13.606 1.00 65.25  ? 396 HIS A CE1    1 
ATOM   6159  N NE2    . HIS A 1 396 ? -44.330 -8.347  -13.127 1.00 66.04  ? 396 HIS A NE2    1 
ATOM   6160  H H      . HIS A 1 396 ? -42.976 -11.685 -10.449 1.00 67.49  ? 396 HIS A H      1 
ATOM   6161  H HA     . HIS A 1 396 ? -44.687 -12.773 -12.150 1.00 65.22  ? 396 HIS A HA     1 
ATOM   6162  H HB2    . HIS A 1 396 ? -42.153 -11.624 -12.640 1.00 63.10  ? 396 HIS A HB2    1 
ATOM   6163  H HB3    . HIS A 1 396 ? -43.051 -12.208 -13.811 1.00 63.10  ? 396 HIS A HB3    1 
ATOM   6164  H HD2    . HIS A 1 396 ? -42.489 -8.974  -12.432 1.00 73.82  ? 396 HIS A HD2    1 
ATOM   6165  H HE1    . HIS A 1 396 ? -46.153 -8.697  -13.905 1.00 78.30  ? 396 HIS A HE1    1 
ATOM   6166  H HE2    . HIS A 1 396 ? -44.311 -7.492  -13.037 1.00 79.25  ? 396 HIS A HE2    1 
ATOM   6167  N N      . ARG A 1 397 ? -43.854 -15.031 -12.739 1.00 50.48  ? 397 ARG A N      1 
ATOM   6168  C CA     . ARG A 1 397 ? -43.410 -16.420 -12.848 1.00 55.12  ? 397 ARG A CA     1 
ATOM   6169  C C      . ARG A 1 397 ? -43.110 -16.780 -14.295 1.00 49.44  ? 397 ARG A C      1 
ATOM   6170  O O      . ARG A 1 397 ? -44.002 -17.198 -15.031 1.00 52.87  ? 397 ARG A O      1 
ATOM   6171  C CB     . ARG A 1 397 ? -44.459 -17.366 -12.263 1.00 55.62  ? 397 ARG A CB     1 
ATOM   6172  C CG     . ARG A 1 397 ? -44.551 -17.246 -10.756 1.00 57.34  ? 397 ARG A CG     1 
ATOM   6173  C CD     . ARG A 1 397 ? -45.568 -18.177 -10.147 1.00 67.58  ? 397 ARG A CD     1 
ATOM   6174  N NE     . ARG A 1 397 ? -45.726 -17.888 -8.725  1.00 74.34  ? 397 ARG A NE     1 
ATOM   6175  C CZ     . ARG A 1 397 ? -45.017 -18.451 -7.752  1.00 77.85  ? 397 ARG A CZ     1 
ATOM   6176  N NH1    . ARG A 1 397 ? -44.086 -19.362 -8.023  1.00 71.25  ? 397 ARG A NH1    1 
ATOM   6177  N NH2    . ARG A 1 397 ? -45.250 -18.101 -6.496  1.00 76.81  ? 397 ARG A NH2    1 
ATOM   6178  H H      . ARG A 1 397 ? -44.596 -14.867 -13.141 1.00 60.58  ? 397 ARG A H      1 
ATOM   6179  H HA     . ARG A 1 397 ? -42.609 -16.548 -12.322 1.00 66.14  ? 397 ARG A HA     1 
ATOM   6180  H HB2    . ARG A 1 397 ? -45.327 -17.150 -12.637 1.00 66.74  ? 397 ARG A HB2    1 
ATOM   6181  H HB3    . ARG A 1 397 ? -44.220 -18.281 -12.480 1.00 66.74  ? 397 ARG A HB3    1 
ATOM   6182  H HG2    . ARG A 1 397 ? -43.686 -17.456 -10.370 1.00 68.81  ? 397 ARG A HG2    1 
ATOM   6183  H HG3    . ARG A 1 397 ? -44.803 -16.338 -10.528 1.00 68.81  ? 397 ARG A HG3    1 
ATOM   6184  H HD2    . ARG A 1 397 ? -46.425 -18.043 -10.581 1.00 81.09  ? 397 ARG A HD2    1 
ATOM   6185  H HD3    . ARG A 1 397 ? -45.277 -19.096 -10.255 1.00 81.09  ? 397 ARG A HD3    1 
ATOM   6186  H HE     . ARG A 1 397 ? -46.322 -17.310 -8.500  1.00 89.20  ? 397 ARG A HE     1 
ATOM   6187  H HH11   . ARG A 1 397 ? -43.928 -19.593 -8.835  1.00 85.50  ? 397 ARG A HH11   1 
ATOM   6188  H HH12   . ARG A 1 397 ? -43.637 -19.718 -7.382  1.00 85.50  ? 397 ARG A HH12   1 
ATOM   6189  H HH21   . ARG A 1 397 ? -45.854 -17.515 -6.320  1.00 92.17  ? 397 ARG A HH21   1 
ATOM   6190  H HH22   . ARG A 1 397 ? -44.807 -18.459 -5.860  1.00 92.17  ? 397 ARG A HH22   1 
ATOM   6191  N N      . PRO A 1 398 ? -41.842 -16.616 -14.710 1.00 49.64  ? 398 PRO A N      1 
ATOM   6192  C CA     . PRO A 1 398 ? -41.466 -16.899 -16.096 1.00 45.82  ? 398 PRO A CA     1 
ATOM   6193  C C      . PRO A 1 398 ? -41.387 -18.395 -16.352 1.00 46.28  ? 398 PRO A C      1 
ATOM   6194  O O      . PRO A 1 398 ? -41.044 -19.152 -15.441 1.00 40.83  ? 398 PRO A O      1 
ATOM   6195  C CB     . PRO A 1 398 ? -40.091 -16.245 -16.221 1.00 48.50  ? 398 PRO A CB     1 
ATOM   6196  C CG     . PRO A 1 398 ? -39.506 -16.389 -14.845 1.00 47.90  ? 398 PRO A CG     1 
ATOM   6197  C CD     . PRO A 1 398 ? -40.671 -16.244 -13.892 1.00 49.21  ? 398 PRO A CD     1 
ATOM   6198  H HA     . PRO A 1 398 ? -42.087 -16.487 -16.716 1.00 54.98  ? 398 PRO A HA     1 
ATOM   6199  H HB2    . PRO A 1 398 ? -39.557 -16.719 -16.877 1.00 58.20  ? 398 PRO A HB2    1 
ATOM   6200  H HB3    . PRO A 1 398 ? -40.189 -15.310 -16.461 1.00 58.20  ? 398 PRO A HB3    1 
ATOM   6201  H HG2    . PRO A 1 398 ? -39.097 -17.264 -14.755 1.00 57.48  ? 398 PRO A HG2    1 
ATOM   6202  H HG3    . PRO A 1 398 ? -38.852 -15.689 -14.694 1.00 57.48  ? 398 PRO A HG3    1 
ATOM   6203  H HD2    . PRO A 1 398 ? -40.570 -16.856 -13.146 1.00 59.05  ? 398 PRO A HD2    1 
ATOM   6204  H HD3    . PRO A 1 398 ? -40.748 -15.325 -13.591 1.00 59.05  ? 398 PRO A HD3    1 
ATOM   6205  N N      . LYS A 1 399 ? -41.707 -18.819 -17.569 1.00 44.44  ? 399 LYS A N      1 
ATOM   6206  C CA     . LYS A 1 399 ? -41.632 -20.234 -17.896 1.00 47.12  ? 399 LYS A CA     1 
ATOM   6207  C C      . LYS A 1 399 ? -40.185 -20.703 -17.828 1.00 45.31  ? 399 LYS A C      1 
ATOM   6208  O O      . LYS A 1 399 ? -39.909 -21.816 -17.385 1.00 45.30  ? 399 LYS A O      1 
ATOM   6209  C CB     . LYS A 1 399 ? -42.234 -20.503 -19.278 1.00 51.26  ? 399 LYS A CB     1 
ATOM   6210  C CG     . LYS A 1 399 ? -43.759 -20.427 -19.286 1.00 80.82  ? 399 LYS A CG     1 
ATOM   6211  C CD     . LYS A 1 399 ? -44.368 -20.986 -20.564 1.00 93.06  ? 399 LYS A CD     1 
ATOM   6212  C CE     . LYS A 1 399 ? -45.893 -20.969 -20.501 1.00 77.67  ? 399 LYS A CE     1 
ATOM   6213  N NZ     . LYS A 1 399 ? -46.521 -21.470 -21.756 1.00 74.93  ? 399 LYS A NZ     1 
ATOM   6214  H H      . LYS A 1 399 ? -41.967 -18.314 -18.215 1.00 53.32  ? 399 LYS A H      1 
ATOM   6215  H HA     . LYS A 1 399 ? -42.142 -20.738 -17.243 1.00 56.55  ? 399 LYS A HA     1 
ATOM   6216  H HB2    . LYS A 1 399 ? -41.898 -19.842 -19.903 1.00 61.51  ? 399 LYS A HB2    1 
ATOM   6217  H HB3    . LYS A 1 399 ? -41.977 -21.393 -19.567 1.00 61.51  ? 399 LYS A HB3    1 
ATOM   6218  H HG2    . LYS A 1 399 ? -44.105 -20.940 -18.539 1.00 96.98  ? 399 LYS A HG2    1 
ATOM   6219  H HG3    . LYS A 1 399 ? -44.030 -19.499 -19.205 1.00 96.98  ? 399 LYS A HG3    1 
ATOM   6220  H HD2    . LYS A 1 399 ? -44.088 -20.443 -21.318 1.00 111.67 ? 399 LYS A HD2    1 
ATOM   6221  H HD3    . LYS A 1 399 ? -44.078 -21.904 -20.683 1.00 111.67 ? 399 LYS A HD3    1 
ATOM   6222  H HE2    . LYS A 1 399 ? -46.186 -21.536 -19.771 1.00 93.20  ? 399 LYS A HE2    1 
ATOM   6223  H HE3    . LYS A 1 399 ? -46.194 -20.058 -20.357 1.00 93.20  ? 399 LYS A HE3    1 
ATOM   6224  H HZ1    . LYS A 1 399 ? -47.408 -21.446 -21.683 1.00 89.91  ? 399 LYS A HZ1    1 
ATOM   6225  H HZ2    . LYS A 1 399 ? -46.273 -20.962 -22.444 1.00 89.91  ? 399 LYS A HZ2    1 
ATOM   6226  H HZ3    . LYS A 1 399 ? -46.266 -22.309 -21.909 1.00 89.91  ? 399 LYS A HZ3    1 
ATOM   6227  N N      . LEU A 1 400 ? -39.263 -19.841 -18.247 1.00 39.89  ? 400 LEU A N      1 
ATOM   6228  C CA     . LEU A 1 400 ? -37.841 -20.166 -18.211 1.00 38.95  ? 400 LEU A CA     1 
ATOM   6229  C C      . LEU A 1 400 ? -37.209 -19.804 -16.871 1.00 35.26  ? 400 LEU A C      1 
ATOM   6230  O O      . LEU A 1 400 ? -37.073 -18.634 -16.530 1.00 36.95  ? 400 LEU A O      1 
ATOM   6231  C CB     . LEU A 1 400 ? -37.099 -19.448 -19.337 1.00 42.20  ? 400 LEU A CB     1 
ATOM   6232  C CG     . LEU A 1 400 ? -37.418 -19.924 -20.757 1.00 44.13  ? 400 LEU A CG     1 
ATOM   6233  C CD1    . LEU A 1 400 ? -36.711 -19.046 -21.778 1.00 46.89  ? 400 LEU A CD1    1 
ATOM   6234  C CD2    . LEU A 1 400 ? -37.032 -21.390 -20.944 1.00 40.53  ? 400 LEU A CD2    1 
ATOM   6235  H H      . LEU A 1 400 ? -39.436 -19.058 -18.558 1.00 47.87  ? 400 LEU A H      1 
ATOM   6236  H HA     . LEU A 1 400 ? -37.729 -21.120 -18.341 1.00 46.74  ? 400 LEU A HA     1 
ATOM   6237  H HB2    . LEU A 1 400 ? -37.316 -18.504 -19.293 1.00 50.64  ? 400 LEU A HB2    1 
ATOM   6238  H HB3    . LEU A 1 400 ? -36.146 -19.566 -19.199 1.00 50.64  ? 400 LEU A HB3    1 
ATOM   6239  H HG     . LEU A 1 400 ? -38.373 -19.846 -20.907 1.00 52.96  ? 400 LEU A HG     1 
ATOM   6240  H HD11   . LEU A 1 400 ? -36.898 -19.383 -22.668 1.00 56.26  ? 400 LEU A HD11   1 
ATOM   6241  H HD12   . LEU A 1 400 ? -37.038 -18.137 -21.693 1.00 56.26  ? 400 LEU A HD12   1 
ATOM   6242  H HD13   . LEU A 1 400 ? -35.756 -19.072 -21.608 1.00 56.26  ? 400 LEU A HD13   1 
ATOM   6243  H HD21   . LEU A 1 400 ? -37.091 -21.614 -21.886 1.00 48.63  ? 400 LEU A HD21   1 
ATOM   6244  H HD22   . LEU A 1 400 ? -36.124 -21.519 -20.629 1.00 48.63  ? 400 LEU A HD22   1 
ATOM   6245  H HD23   . LEU A 1 400 ? -37.641 -21.946 -20.433 1.00 48.63  ? 400 LEU A HD23   1 
ATOM   6246  N N      . GLU A 1 401 ? -36.846 -20.833 -16.118 1.00 29.97  ? 401 GLU A N      1 
ATOM   6247  C CA     . GLU A 1 401 ? -36.086 -20.686 -14.888 1.00 29.40  ? 401 GLU A CA     1 
ATOM   6248  C C      . GLU A 1 401 ? -34.676 -21.197 -15.172 1.00 30.17  ? 401 GLU A C      1 
ATOM   6249  O O      . GLU A 1 401 ? -34.414 -22.396 -15.037 1.00 29.85  ? 401 GLU A O      1 
ATOM   6250  C CB     . GLU A 1 401 ? -36.761 -21.468 -13.756 1.00 29.88  ? 401 GLU A CB     1 
ATOM   6251  C CG     . GLU A 1 401 ? -36.026 -21.486 -12.426 1.00 33.48  ? 401 GLU A CG     1 
ATOM   6252  C CD     . GLU A 1 401 ? -36.124 -20.173 -11.659 1.00 35.35  ? 401 GLU A CD     1 
ATOM   6253  O OE1    . GLU A 1 401 ? -35.421 -20.036 -10.632 1.00 30.00  ? 401 GLU A OE1    1 
ATOM   6254  O OE2    . GLU A 1 401 ? -36.905 -19.291 -12.068 1.00 32.62  ? 401 GLU A OE2    1 
ATOM   6255  H H      . GLU A 1 401 ? -37.035 -21.651 -16.306 1.00 35.96  ? 401 GLU A H      1 
ATOM   6256  H HA     . GLU A 1 401 ? -36.033 -19.753 -14.631 1.00 35.28  ? 401 GLU A HA     1 
ATOM   6257  H HB2    . GLU A 1 401 ? -37.641 -21.090 -13.603 1.00 35.86  ? 401 GLU A HB2    1 
ATOM   6258  H HB3    . GLU A 1 401 ? -36.856 -22.390 -14.042 1.00 35.86  ? 401 GLU A HB3    1 
ATOM   6259  H HG2    . GLU A 1 401 ? -36.414 -22.181 -11.873 1.00 40.18  ? 401 GLU A HG2    1 
ATOM   6260  H HG3    . GLU A 1 401 ? -35.088 -21.672 -12.580 1.00 40.18  ? 401 GLU A HG3    1 
ATOM   6261  N N      . THR A 1 402 ? -33.781 -20.299 -15.591 1.00 26.96  ? 402 THR A N      1 
ATOM   6262  C CA     . THR A 1 402 ? -32.479 -20.723 -16.107 1.00 29.27  ? 402 THR A CA     1 
ATOM   6263  C C      . THR A 1 402 ? -31.279 -20.029 -15.471 1.00 26.57  ? 402 THR A C      1 
ATOM   6264  O O      . THR A 1 402 ? -31.392 -18.969 -14.862 1.00 24.68  ? 402 THR A O      1 
ATOM   6265  C CB     . THR A 1 402 ? -32.380 -20.516 -17.646 1.00 28.55  ? 402 THR A CB     1 
ATOM   6266  O OG1    . THR A 1 402 ? -32.304 -19.117 -17.960 1.00 27.40  ? 402 THR A OG1    1 
ATOM   6267  C CG2    . THR A 1 402 ? -33.577 -21.148 -18.366 1.00 31.81  ? 402 THR A CG2    1 
ATOM   6268  H H      . THR A 1 402 ? -33.902 -19.448 -15.587 1.00 32.36  ? 402 THR A H      1 
ATOM   6269  H HA     . THR A 1 402 ? -32.376 -21.667 -15.933 1.00 35.13  ? 402 THR A HA     1 
ATOM   6270  H HB     . THR A 1 402 ? -31.576 -20.952 -17.969 1.00 34.27  ? 402 THR A HB     1 
ATOM   6271  H HG1    . THR A 1 402 ? -32.990 -18.722 -17.678 1.00 32.88  ? 402 THR A HG1    1 
ATOM   6272  H HG21   . THR A 1 402 ? -33.469 -21.061 -19.326 1.00 38.17  ? 402 THR A HG21   1 
ATOM   6273  H HG22   . THR A 1 402 ? -33.640 -22.089 -18.140 1.00 38.17  ? 402 THR A HG22   1 
ATOM   6274  H HG23   . THR A 1 402 ? -34.397 -20.704 -18.100 1.00 38.17  ? 402 THR A HG23   1 
ATOM   6275  N N      . VAL A 1 403 ? -30.132 -20.684 -15.610 1.00 22.82  ? 403 VAL A N      1 
ATOM   6276  C CA     . VAL A 1 403 ? -28.841 -20.115 -15.254 1.00 19.91  ? 403 VAL A CA     1 
ATOM   6277  C C      . VAL A 1 403 ? -28.073 -19.974 -16.556 1.00 22.61  ? 403 VAL A C      1 
ATOM   6278  O O      . VAL A 1 403 ? -27.902 -20.945 -17.282 1.00 20.58  ? 403 VAL A O      1 
ATOM   6279  C CB     . VAL A 1 403 ? -28.084 -20.998 -14.260 1.00 22.47  ? 403 VAL A CB     1 
ATOM   6280  C CG1    . VAL A 1 403 ? -26.646 -20.509 -14.065 1.00 23.96  ? 403 VAL A CG1    1 
ATOM   6281  C CG2    . VAL A 1 403 ? -28.826 -21.030 -12.931 1.00 24.60  ? 403 VAL A CG2    1 
ATOM   6282  H H      . VAL A 1 403 ? -30.076 -21.485 -15.918 1.00 27.39  ? 403 VAL A H      1 
ATOM   6283  H HA     . VAL A 1 403 ? -28.955 -19.235 -14.864 1.00 23.89  ? 403 VAL A HA     1 
ATOM   6284  H HB     . VAL A 1 403 ? -28.048 -21.904 -14.605 1.00 26.96  ? 403 VAL A HB     1 
ATOM   6285  H HG11   . VAL A 1 403 ? -26.272 -20.939 -13.280 1.00 28.76  ? 403 VAL A HG11   1 
ATOM   6286  H HG12   . VAL A 1 403 ? -26.122 -20.740 -14.848 1.00 28.76  ? 403 VAL A HG12   1 
ATOM   6287  H HG13   . VAL A 1 403 ? -26.654 -19.547 -13.941 1.00 28.76  ? 403 VAL A HG13   1 
ATOM   6288  H HG21   . VAL A 1 403 ? -28.332 -21.585 -12.307 1.00 29.52  ? 403 VAL A HG21   1 
ATOM   6289  H HG22   . VAL A 1 403 ? -28.895 -20.126 -12.587 1.00 29.52  ? 403 VAL A HG22   1 
ATOM   6290  H HG23   . VAL A 1 403 ? -29.712 -21.399 -13.073 1.00 29.52  ? 403 VAL A HG23   1 
ATOM   6291  N N      . ARG A 1 404 ? -27.634 -18.758 -16.857 1.00 18.72  ? 404 ARG A N      1 
ATOM   6292  C CA     . ARG A 1 404 ? -26.961 -18.495 -18.118 1.00 18.18  ? 404 ARG A CA     1 
ATOM   6293  C C      . ARG A 1 404 ? -25.449 -18.552 -17.955 1.00 19.03  ? 404 ARG A C      1 
ATOM   6294  O O      . ARG A 1 404 ? -24.873 -17.837 -17.131 1.00 19.15  ? 404 ARG A O      1 
ATOM   6295  C CB     . ARG A 1 404 ? -27.378 -17.140 -18.666 1.00 21.85  ? 404 ARG A CB     1 
ATOM   6296  C CG     . ARG A 1 404 ? -26.916 -16.896 -20.079 1.00 21.14  ? 404 ARG A CG     1 
ATOM   6297  C CD     . ARG A 1 404 ? -27.404 -15.555 -20.557 1.00 20.19  ? 404 ARG A CD     1 
ATOM   6298  N NE     . ARG A 1 404 ? -26.590 -14.472 -20.007 1.00 22.38  ? 404 ARG A NE     1 
ATOM   6299  C CZ     . ARG A 1 404 ? -26.958 -13.194 -19.969 1.00 22.14  ? 404 ARG A CZ     1 
ATOM   6300  N NH1    . ARG A 1 404 ? -28.148 -12.825 -20.416 1.00 22.47  ? 404 ARG A NH1    1 
ATOM   6301  N NH2    . ARG A 1 404 ? -26.140 -12.285 -19.463 1.00 23.66  ? 404 ARG A NH2    1 
ATOM   6302  H H      . ARG A 1 404 ? -27.714 -18.070 -16.348 1.00 22.47  ? 404 ARG A H      1 
ATOM   6303  H HA     . ARG A 1 404 ? -27.217 -19.165 -18.770 1.00 21.81  ? 404 ARG A HA     1 
ATOM   6304  H HB2    . ARG A 1 404 ? -28.346 -17.082 -18.655 1.00 26.22  ? 404 ARG A HB2    1 
ATOM   6305  H HB3    . ARG A 1 404 ? -27.000 -16.445 -18.105 1.00 26.22  ? 404 ARG A HB3    1 
ATOM   6306  H HG2    . ARG A 1 404 ? -25.947 -16.900 -20.110 1.00 25.37  ? 404 ARG A HG2    1 
ATOM   6307  H HG3    . ARG A 1 404 ? -27.278 -17.582 -20.662 1.00 25.37  ? 404 ARG A HG3    1 
ATOM   6308  H HD2    . ARG A 1 404 ? -27.347 -15.518 -21.525 1.00 24.23  ? 404 ARG A HD2    1 
ATOM   6309  H HD3    . ARG A 1 404 ? -28.321 -15.427 -20.268 1.00 24.23  ? 404 ARG A HD3    1 
ATOM   6310  H HE     . ARG A 1 404 ? -25.819 -14.675 -19.685 1.00 26.86  ? 404 ARG A HE     1 
ATOM   6311  H HH11   . ARG A 1 404 ? -28.686 -13.407 -20.749 1.00 26.96  ? 404 ARG A HH11   1 
ATOM   6312  H HH12   . ARG A 1 404 ? -28.380 -11.998 -20.383 1.00 26.96  ? 404 ARG A HH12   1 
ATOM   6313  H HH21   . ARG A 1 404 ? -25.369 -12.520 -19.164 1.00 28.39  ? 404 ARG A HH21   1 
ATOM   6314  H HH22   . ARG A 1 404 ? -26.382 -11.461 -19.428 1.00 28.39  ? 404 ARG A HH22   1 
ATOM   6315  N N      . LEU A 1 405 ? -24.832 -19.430 -18.737 1.00 17.75  ? 405 LEU A N      1 
ATOM   6316  C CA     . LEU A 1 405 ? -23.381 -19.542 -18.841 1.00 18.93  ? 405 LEU A CA     1 
ATOM   6317  C C      . LEU A 1 405 ? -22.970 -18.797 -20.114 1.00 20.35  ? 405 LEU A C      1 
ATOM   6318  O O      . LEU A 1 405 ? -22.996 -19.361 -21.207 1.00 17.08  ? 405 LEU A O      1 
ATOM   6319  C CB     . LEU A 1 405 ? -22.945 -21.012 -18.893 1.00 18.50  ? 405 LEU A CB     1 
ATOM   6320  C CG     . LEU A 1 405 ? -23.485 -21.931 -17.787 1.00 20.82  ? 405 LEU A CG     1 
ATOM   6321  C CD1    . LEU A 1 405 ? -23.212 -23.400 -18.128 1.00 21.43  ? 405 LEU A CD1    1 
ATOM   6322  C CD2    . LEU A 1 405 ? -22.877 -21.576 -16.449 1.00 19.40  ? 405 LEU A CD2    1 
ATOM   6323  H H      . LEU A 1 405 ? -25.249 -19.993 -19.236 1.00 21.30  ? 405 LEU A H      1 
ATOM   6324  H HA     . LEU A 1 405 ? -22.957 -19.118 -18.079 1.00 22.71  ? 405 LEU A HA     1 
ATOM   6325  H HB2    . LEU A 1 405 ? -23.235 -21.387 -19.739 1.00 22.20  ? 405 LEU A HB2    1 
ATOM   6326  H HB3    . LEU A 1 405 ? -21.977 -21.043 -18.844 1.00 22.20  ? 405 LEU A HB3    1 
ATOM   6327  H HG     . LEU A 1 405 ? -24.445 -21.814 -17.720 1.00 24.98  ? 405 LEU A HG     1 
ATOM   6328  H HD11   . LEU A 1 405 ? -23.564 -23.959 -17.418 1.00 25.71  ? 405 LEU A HD11   1 
ATOM   6329  H HD12   . LEU A 1 405 ? -23.649 -23.616 -18.967 1.00 25.71  ? 405 LEU A HD12   1 
ATOM   6330  H HD13   . LEU A 1 405 ? -22.255 -23.532 -18.210 1.00 25.71  ? 405 LEU A HD13   1 
ATOM   6331  H HD21   . LEU A 1 405 ? -23.264 -22.145 -15.765 1.00 23.28  ? 405 LEU A HD21   1 
ATOM   6332  H HD22   . LEU A 1 405 ? -21.918 -21.713 -16.492 1.00 23.28  ? 405 LEU A HD22   1 
ATOM   6333  H HD23   . LEU A 1 405 ? -23.071 -20.646 -16.255 1.00 23.28  ? 405 LEU A HD23   1 
ATOM   6334  N N      . THR A 1 406 ? -22.608 -17.526 -19.965 1.00 16.35  ? 406 THR A N      1 
ATOM   6335  C CA     . THR A 1 406 ? -22.359 -16.645 -21.107 1.00 16.19  ? 406 THR A CA     1 
ATOM   6336  C C      . THR A 1 406 ? -20.859 -16.545 -21.357 1.00 19.62  ? 406 THR A C      1 
ATOM   6337  O O      . THR A 1 406 ? -20.091 -16.208 -20.449 1.00 18.61  ? 406 THR A O      1 
ATOM   6338  C CB     . THR A 1 406 ? -22.943 -15.243 -20.870 1.00 20.87  ? 406 THR A CB     1 
ATOM   6339  O OG1    . THR A 1 406 ? -23.870 -15.284 -19.782 1.00 20.35  ? 406 THR A OG1    1 
ATOM   6340  C CG2    . THR A 1 406 ? -23.658 -14.736 -22.096 1.00 18.50  ? 406 THR A CG2    1 
ATOM   6341  H H      . THR A 1 406 ? -22.497 -17.144 -19.203 1.00 19.63  ? 406 THR A H      1 
ATOM   6342  H HA     . THR A 1 406 ? -22.776 -17.013 -21.901 1.00 19.42  ? 406 THR A HA     1 
ATOM   6343  H HB     . THR A 1 406 ? -22.222 -14.631 -20.659 1.00 25.05  ? 406 THR A HB     1 
ATOM   6344  H HG1    . THR A 1 406 ? -23.463 -15.425 -19.061 1.00 24.42  ? 406 THR A HG1    1 
ATOM   6345  H HG21   . THR A 1 406 ? -23.936 -13.817 -21.961 1.00 22.20  ? 406 THR A HG21   1 
ATOM   6346  H HG22   . THR A 1 406 ? -23.068 -14.777 -22.865 1.00 22.20  ? 406 THR A HG22   1 
ATOM   6347  H HG23   . THR A 1 406 ? -24.442 -15.280 -22.271 1.00 22.20  ? 406 THR A HG23   1 
ATOM   6348  N N      . ILE A 1 407 ? -20.441 -16.838 -22.587 1.00 17.92  ? 407 ILE A N      1 
ATOM   6349  C CA     . ILE A 1 407 ? -19.022 -17.000 -22.892 1.00 14.86  ? 407 ILE A CA     1 
ATOM   6350  C C      . ILE A 1 407 ? -18.432 -15.758 -23.568 1.00 14.25  ? 407 ILE A C      1 
ATOM   6351  O O      . ILE A 1 407 ? -18.737 -15.483 -24.725 1.00 14.39  ? 407 ILE A O      1 
ATOM   6352  C CB     . ILE A 1 407 ? -18.788 -18.215 -23.802 1.00 14.54  ? 407 ILE A CB     1 
ATOM   6353  C CG1    . ILE A 1 407 ? -19.538 -19.438 -23.267 1.00 18.02  ? 407 ILE A CG1    1 
ATOM   6354  C CG2    . ILE A 1 407 ? -17.304 -18.507 -23.935 1.00 19.80  ? 407 ILE A CG2    1 
ATOM   6355  C CD1    . ILE A 1 407 ? -19.264 -19.746 -21.795 1.00 18.84  ? 407 ILE A CD1    1 
ATOM   6356  H H      . ILE A 1 407 ? -20.960 -16.948 -23.263 1.00 21.50  ? 407 ILE A H      1 
ATOM   6357  H HA     . ILE A 1 407 ? -18.538 -17.167 -22.071 1.00 17.83  ? 407 ILE A HA     1 
ATOM   6358  H HB     . ILE A 1 407 ? -19.137 -18.008 -24.683 1.00 17.44  ? 407 ILE A HB     1 
ATOM   6359  H HG12   . ILE A 1 407 ? -20.491 -19.290 -23.367 1.00 21.62  ? 407 ILE A HG12   1 
ATOM   6360  H HG13   . ILE A 1 407 ? -19.273 -20.215 -23.784 1.00 21.62  ? 407 ILE A HG13   1 
ATOM   6361  H HG21   . ILE A 1 407 ? -17.191 -19.371 -24.361 1.00 23.76  ? 407 ILE A HG21   1 
ATOM   6362  H HG22   . ILE A 1 407 ? -16.892 -17.816 -24.476 1.00 23.76  ? 407 ILE A HG22   1 
ATOM   6363  H HG23   . ILE A 1 407 ? -16.904 -18.520 -23.051 1.00 23.76  ? 407 ILE A HG23   1 
ATOM   6364  H HD11   . ILE A 1 407 ? -19.639 -20.614 -21.580 1.00 22.60  ? 407 ILE A HD11   1 
ATOM   6365  H HD12   . ILE A 1 407 ? -18.305 -19.755 -21.647 1.00 22.60  ? 407 ILE A HD12   1 
ATOM   6366  H HD13   . ILE A 1 407 ? -19.677 -19.063 -21.245 1.00 22.60  ? 407 ILE A HD13   1 
ATOM   6367  N N      . PRO A 1 408 ? -17.580 -15.006 -22.850 1.00 15.25  ? 408 PRO A N      1 
ATOM   6368  C CA     . PRO A 1 408 ? -16.850 -13.918 -23.516 1.00 15.70  ? 408 PRO A CA     1 
ATOM   6369  C C      . PRO A 1 408 ? -15.971 -14.446 -24.662 1.00 16.56  ? 408 PRO A C      1 
ATOM   6370  O O      . PRO A 1 408 ? -15.550 -15.597 -24.611 1.00 17.99  ? 408 PRO A O      1 
ATOM   6371  C CB     . PRO A 1 408 ? -15.976 -13.333 -22.396 1.00 15.16  ? 408 PRO A CB     1 
ATOM   6372  C CG     . PRO A 1 408 ? -16.638 -13.758 -21.120 1.00 17.13  ? 408 PRO A CG     1 
ATOM   6373  C CD     . PRO A 1 408 ? -17.191 -15.126 -21.434 1.00 15.45  ? 408 PRO A CD     1 
ATOM   6374  H HA     . PRO A 1 408 ? -17.461 -13.241 -23.848 1.00 18.85  ? 408 PRO A HA     1 
ATOM   6375  H HB2    . PRO A 1 408 ? -15.080 -13.700 -22.456 1.00 18.19  ? 408 PRO A HB2    1 
ATOM   6376  H HB3    . PRO A 1 408 ? -15.955 -12.366 -22.468 1.00 18.19  ? 408 PRO A HB3    1 
ATOM   6377  H HG2    . PRO A 1 408 ? -15.982 -13.805 -20.407 1.00 20.55  ? 408 PRO A HG2    1 
ATOM   6378  H HG3    . PRO A 1 408 ? -17.351 -13.140 -20.896 1.00 20.55  ? 408 PRO A HG3    1 
ATOM   6379  H HD2    . PRO A 1 408 ? -16.504 -15.803 -21.326 1.00 18.54  ? 408 PRO A HD2    1 
ATOM   6380  H HD3    . PRO A 1 408 ? -17.959 -15.306 -20.877 1.00 18.54  ? 408 PRO A HD3    1 
ATOM   6381  N N      . ARG A 1 409 ? -15.681 -13.615 -25.654 1.00 14.99  ? 409 ARG A N      1 
ATOM   6382  C CA     . ARG A 1 409 ? -14.875 -14.034 -26.791 1.00 14.15  ? 409 ARG A CA     1 
ATOM   6383  C C      . ARG A 1 409 ? -13.372 -13.962 -26.527 1.00 16.36  ? 409 ARG A C      1 
ATOM   6384  O O      . ARG A 1 409 ? -12.856 -12.932 -26.096 1.00 16.20  ? 409 ARG A O      1 
ATOM   6385  C CB     . ARG A 1 409 ? -15.234 -13.180 -28.013 1.00 15.43  ? 409 ARG A CB     1 
ATOM   6386  C CG     . ARG A 1 409 ? -16.705 -13.296 -28.411 1.00 16.25  ? 409 ARG A CG     1 
ATOM   6387  C CD     . ARG A 1 409 ? -17.217 -12.136 -29.253 1.00 18.35  ? 409 ARG A CD     1 
ATOM   6388  N NE     . ARG A 1 409 ? -18.662 -12.238 -29.418 1.00 17.57  ? 409 ARG A NE     1 
ATOM   6389  C CZ     . ARG A 1 409 ? -19.548 -11.891 -28.488 1.00 19.67  ? 409 ARG A CZ     1 
ATOM   6390  N NH1    . ARG A 1 409 ? -19.147 -11.401 -27.314 1.00 17.13  ? 409 ARG A NH1    1 
ATOM   6391  N NH2    . ARG A 1 409 ? -20.843 -12.053 -28.721 1.00 19.85  ? 409 ARG A NH2    1 
ATOM   6392  H H      . ARG A 1 409 ? -15.941 -12.796 -25.692 1.00 17.99  ? 409 ARG A H      1 
ATOM   6393  H HA     . ARG A 1 409 ? -15.092 -14.955 -27.005 1.00 16.98  ? 409 ARG A HA     1 
ATOM   6394  H HB2    . ARG A 1 409 ? -15.046 -12.250 -27.817 1.00 18.52  ? 409 ARG A HB2    1 
ATOM   6395  H HB3    . ARG A 1 409 ? -14.698 -13.472 -28.767 1.00 18.52  ? 409 ARG A HB3    1 
ATOM   6396  H HG2    . ARG A 1 409 ? -16.824 -14.109 -28.927 1.00 19.51  ? 409 ARG A HG2    1 
ATOM   6397  H HG3    . ARG A 1 409 ? -17.248 -13.337 -27.608 1.00 19.51  ? 409 ARG A HG3    1 
ATOM   6398  H HD2    . ARG A 1 409 ? -17.016 -11.299 -28.807 1.00 22.03  ? 409 ARG A HD2    1 
ATOM   6399  H HD3    . ARG A 1 409 ? -16.807 -12.156 -30.129 1.00 22.03  ? 409 ARG A HD3    1 
ATOM   6400  H HE     . ARG A 1 409 ? -18.961 -12.542 -30.165 1.00 21.08  ? 409 ARG A HE     1 
ATOM   6401  H HH11   . ARG A 1 409 ? -18.309 -11.302 -27.149 1.00 20.55  ? 409 ARG A HH11   1 
ATOM   6402  H HH12   . ARG A 1 409 ? -19.729 -11.179 -26.721 1.00 20.55  ? 409 ARG A HH12   1 
ATOM   6403  H HH21   . ARG A 1 409 ? -21.108 -12.365 -29.478 1.00 23.83  ? 409 ARG A HH21   1 
ATOM   6404  H HH22   . ARG A 1 409 ? -21.419 -11.821 -28.126 1.00 23.83  ? 409 ARG A HH22   1 
ATOM   6405  N N      . ARG A 1 410 ? -12.698 -15.079 -26.802 1.00 14.93  ? 410 ARG A N      1 
ATOM   6406  C CA     . ARG A 1 410 ? -11.242 -15.219 -26.750 1.00 17.55  ? 410 ARG A CA     1 
ATOM   6407  C C      . ARG A 1 410 ? -10.645 -15.124 -25.331 1.00 18.95  ? 410 ARG A C      1 
ATOM   6408  O O      . ARG A 1 410 ? -9.446  -14.892 -25.177 1.00 17.85  ? 410 ARG A O      1 
ATOM   6409  C CB     . ARG A 1 410 ? -10.585 -14.170 -27.669 1.00 15.90  ? 410 ARG A CB     1 
ATOM   6410  C CG     . ARG A 1 410 ? -11.108 -14.272 -29.118 1.00 16.48  ? 410 ARG A CG     1 
ATOM   6411  C CD     . ARG A 1 410 ? -10.227 -13.566 -30.148 1.00 16.44  ? 410 ARG A CD     1 
ATOM   6412  N NE     . ARG A 1 410 ? -10.165 -12.133 -29.884 1.00 13.40  ? 410 ARG A NE     1 
ATOM   6413  C CZ     . ARG A 1 410 ? -9.818  -11.198 -30.771 1.00 16.92  ? 410 ARG A CZ     1 
ATOM   6414  N NH1    . ARG A 1 410 ? -9.478  -11.516 -32.014 1.00 17.37  ? 410 ARG A NH1    1 
ATOM   6415  N NH2    . ARG A 1 410 ? -9.813  -9.924  -30.408 1.00 16.41  ? 410 ARG A NH2    1 
ATOM   6416  H H      . ARG A 1 410 ? -13.088 -15.810 -27.034 1.00 17.92  ? 410 ARG A H      1 
ATOM   6417  H HA     . ARG A 1 410 ? -11.013 -16.093 -27.097 1.00 21.06  ? 410 ARG A HA     1 
ATOM   6418  H HB2    . ARG A 1 410 ? -10.774 -13.279 -27.338 1.00 19.08  ? 410 ARG A HB2    1 
ATOM   6419  H HB3    . ARG A 1 410 ? -9.627  -14.321 -27.687 1.00 19.08  ? 410 ARG A HB3    1 
ATOM   6420  H HG2    . ARG A 1 410 ? -11.160 -15.208 -29.366 1.00 19.78  ? 410 ARG A HG2    1 
ATOM   6421  H HG3    . ARG A 1 410 ? -11.991 -13.872 -29.160 1.00 19.78  ? 410 ARG A HG3    1 
ATOM   6422  H HD2    . ARG A 1 410 ? -9.327  -13.925 -30.102 1.00 19.72  ? 410 ARG A HD2    1 
ATOM   6423  H HD3    . ARG A 1 410 ? -10.599 -13.699 -31.034 1.00 19.72  ? 410 ARG A HD3    1 
ATOM   6424  H HE     . ARG A 1 410 ? -10.369 -11.869 -29.092 1.00 16.08  ? 410 ARG A HE     1 
ATOM   6425  H HH11   . ARG A 1 410 ? -9.480  -12.338 -32.265 1.00 20.84  ? 410 ARG A HH11   1 
ATOM   6426  H HH12   . ARG A 1 410 ? -9.256  -10.898 -32.570 1.00 20.84  ? 410 ARG A HH12   1 
ATOM   6427  H HH21   . ARG A 1 410 ? -10.029 -9.705  -29.605 1.00 19.69  ? 410 ARG A HH21   1 
ATOM   6428  H HH22   . ARG A 1 410 ? -9.586  -9.317  -30.973 1.00 19.69  ? 410 ARG A HH22   1 
ATOM   6429  N N      . VAL A 1 411 ? -11.462 -15.326 -24.301 1.00 13.63  ? 411 VAL A N      1 
ATOM   6430  C CA     . VAL A 1 411 ? -10.986 -15.129 -22.925 1.00 14.77  ? 411 VAL A CA     1 
ATOM   6431  C C      . VAL A 1 411 ? -10.631 -16.438 -22.229 1.00 17.85  ? 411 VAL A C      1 
ATOM   6432  O O      . VAL A 1 411 ? -9.679  -16.487 -21.440 1.00 16.06  ? 411 VAL A O      1 
ATOM   6433  C CB     . VAL A 1 411 ? -12.034 -14.382 -22.081 1.00 14.75  ? 411 VAL A CB     1 
ATOM   6434  C CG1    . VAL A 1 411 ? -11.604 -14.280 -20.621 1.00 17.76  ? 411 VAL A CG1    1 
ATOM   6435  C CG2    . VAL A 1 411 ? -12.259 -12.993 -22.643 1.00 15.01  ? 411 VAL A CG2    1 
ATOM   6436  H H      . VAL A 1 411 ? -12.283 -15.573 -24.365 1.00 16.36  ? 411 VAL A H      1 
ATOM   6437  H HA     . VAL A 1 411 ? -10.189 -14.578 -22.936 1.00 17.73  ? 411 VAL A HA     1 
ATOM   6438  H HB     . VAL A 1 411 ? -12.875 -14.864 -22.117 1.00 17.70  ? 411 VAL A HB     1 
ATOM   6439  H HG11   . VAL A 1 411 ? -12.141 -13.601 -20.182 1.00 21.31  ? 411 VAL A HG11   1 
ATOM   6440  H HG12   . VAL A 1 411 ? -11.739 -15.137 -20.187 1.00 21.31  ? 411 VAL A HG12   1 
ATOM   6441  H HG13   . VAL A 1 411 ? -10.667 -14.032 -20.585 1.00 21.31  ? 411 VAL A HG13   1 
ATOM   6442  H HG21   . VAL A 1 411 ? -12.891 -12.526 -22.076 1.00 18.02  ? 411 VAL A HG21   1 
ATOM   6443  H HG22   . VAL A 1 411 ? -11.413 -12.518 -22.660 1.00 18.02  ? 411 VAL A HG22   1 
ATOM   6444  H HG23   . VAL A 1 411 ? -12.614 -13.069 -23.542 1.00 18.02  ? 411 VAL A HG23   1 
ATOM   6445  N N      . TYR A 1 412 ? -11.403 -17.489 -22.510 1.00 14.11  ? 412 TYR A N      1 
ATOM   6446  C CA     . TYR A 1 412 ? -11.266 -18.772 -21.810 1.00 15.23  ? 412 TYR A CA     1 
ATOM   6447  C C      . TYR A 1 412 ? -10.871 -19.886 -22.778 1.00 20.15  ? 412 TYR A C      1 
ATOM   6448  O O      . TYR A 1 412 ? -10.926 -19.718 -23.996 1.00 16.48  ? 412 TYR A O      1 
ATOM   6449  C CB     . TYR A 1 412 ? -12.577 -19.113 -21.074 1.00 15.29  ? 412 TYR A CB     1 
ATOM   6450  C CG     . TYR A 1 412 ? -12.909 -18.060 -20.042 1.00 14.82  ? 412 TYR A CG     1 
ATOM   6451  C CD1    . TYR A 1 412 ? -12.130 -17.915 -18.897 1.00 17.99  ? 412 TYR A CD1    1 
ATOM   6452  C CD2    . TYR A 1 412 ? -13.961 -17.181 -20.233 1.00 16.52  ? 412 TYR A CD2    1 
ATOM   6453  C CE1    . TYR A 1 412 ? -12.407 -16.920 -17.960 1.00 15.49  ? 412 TYR A CE1    1 
ATOM   6454  C CE2    . TYR A 1 412 ? -14.242 -16.186 -19.303 1.00 17.77  ? 412 TYR A CE2    1 
ATOM   6455  C CZ     . TYR A 1 412 ? -13.467 -16.067 -18.169 1.00 16.28  ? 412 TYR A CZ     1 
ATOM   6456  O OH     . TYR A 1 412 ? -13.744 -15.070 -17.248 1.00 16.69  ? 412 TYR A OH     1 
ATOM   6457  H H      . TYR A 1 412 ? -12.021 -17.486 -23.108 1.00 16.94  ? 412 TYR A H      1 
ATOM   6458  H HA     . TYR A 1 412 ? -10.566 -18.705 -21.143 1.00 18.27  ? 412 TYR A HA     1 
ATOM   6459  H HB2    . TYR A 1 412 ? -13.304 -19.153 -21.714 1.00 18.35  ? 412 TYR A HB2    1 
ATOM   6460  H HB3    . TYR A 1 412 ? -12.479 -19.965 -20.621 1.00 18.35  ? 412 TYR A HB3    1 
ATOM   6461  H HD1    . TYR A 1 412 ? -11.412 -18.489 -18.756 1.00 21.58  ? 412 TYR A HD1    1 
ATOM   6462  H HD2    . TYR A 1 412 ? -14.486 -17.254 -20.997 1.00 19.82  ? 412 TYR A HD2    1 
ATOM   6463  H HE1    . TYR A 1 412 ? -11.883 -16.837 -17.196 1.00 18.59  ? 412 TYR A HE1    1 
ATOM   6464  H HE2    . TYR A 1 412 ? -14.956 -15.606 -19.442 1.00 21.32  ? 412 TYR A HE2    1 
ATOM   6465  H HH     . TYR A 1 412 ? -13.181 -15.091 -16.625 1.00 20.03  ? 412 TYR A HH     1 
ATOM   6466  N N      . THR A 1 413 ? -10.456 -21.017 -22.213 1.00 16.46  ? 413 THR A N      1 
ATOM   6467  C CA     . THR A 1 413 ? -9.971  -22.147 -22.982 1.00 18.16  ? 413 THR A CA     1 
ATOM   6468  C C      . THR A 1 413 ? -10.930 -23.318 -22.821 1.00 17.85  ? 413 THR A C      1 
ATOM   6469  O O      . THR A 1 413 ? -11.877 -23.244 -22.029 1.00 16.43  ? 413 THR A O      1 
ATOM   6470  C CB     . THR A 1 413 ? -8.566  -22.595 -22.520 1.00 19.47  ? 413 THR A CB     1 
ATOM   6471  O OG1    . THR A 1 413 ? -8.680  -23.293 -21.273 1.00 20.14  ? 413 THR A OG1    1 
ATOM   6472  C CG2    . THR A 1 413 ? -7.629  -21.406 -22.346 1.00 17.10  ? 413 THR A CG2    1 
ATOM   6473  H H      . THR A 1 413 ? -10.460 -21.159 -21.369 1.00 19.75  ? 413 THR A H      1 
ATOM   6474  H HA     . THR A 1 413 ? -9.923  -21.918 -23.923 1.00 21.79  ? 413 THR A HA     1 
ATOM   6475  H HB     . THR A 1 413 ? -8.184  -23.188 -23.185 1.00 23.36  ? 413 THR A HB     1 
ATOM   6476  H HG1    . THR A 1 413 ? -9.017  -22.789 -20.691 1.00 24.17  ? 413 THR A HG1    1 
ATOM   6477  H HG21   . THR A 1 413 ? -6.730  -21.718 -22.160 1.00 20.53  ? 413 THR A HG21   1 
ATOM   6478  H HG22   . THR A 1 413 ? -7.616  -20.874 -23.157 1.00 20.53  ? 413 THR A HG22   1 
ATOM   6479  H HG23   . THR A 1 413 ? -7.929  -20.851 -21.609 1.00 20.53  ? 413 THR A HG23   1 
ATOM   6480  N N      . TYR A 1 414 ? -10.666 -24.405 -23.548 1.00 14.76  ? 414 TYR A N      1 
ATOM   6481  C CA     . TYR A 1 414 ? -11.410 -25.646 -23.345 1.00 18.63  ? 414 TYR A CA     1 
ATOM   6482  C C      . TYR A 1 414 ? -11.215 -26.193 -21.934 1.00 18.93  ? 414 TYR A C      1 
ATOM   6483  O O      . TYR A 1 414 ? -12.110 -26.841 -21.389 1.00 18.77  ? 414 TYR A O      1 
ATOM   6484  C CB     . TYR A 1 414 ? -10.988 -26.719 -24.352 1.00 17.37  ? 414 TYR A CB     1 
ATOM   6485  C CG     . TYR A 1 414 ? -11.465 -26.498 -25.777 1.00 19.61  ? 414 TYR A CG     1 
ATOM   6486  C CD1    . TYR A 1 414 ? -12.816 -26.484 -26.089 1.00 18.25  ? 414 TYR A CD1    1 
ATOM   6487  C CD2    . TYR A 1 414 ? -10.557 -26.360 -26.811 1.00 21.77  ? 414 TYR A CD2    1 
ATOM   6488  C CE1    . TYR A 1 414 ? -13.250 -26.306 -27.392 1.00 18.15  ? 414 TYR A CE1    1 
ATOM   6489  C CE2    . TYR A 1 414 ? -10.979 -26.178 -28.116 1.00 20.92  ? 414 TYR A CE2    1 
ATOM   6490  C CZ     . TYR A 1 414 ? -12.323 -26.151 -28.402 1.00 18.51  ? 414 TYR A CZ     1 
ATOM   6491  O OH     . TYR A 1 414 ? -12.745 -25.979 -29.701 1.00 19.33  ? 414 TYR A OH     1 
ATOM   6492  H H      . TYR A 1 414 ? -10.065 -24.449 -24.161 1.00 17.71  ? 414 TYR A H      1 
ATOM   6493  H HA     . TYR A 1 414 ? -12.356 -25.471 -23.471 1.00 22.36  ? 414 TYR A HA     1 
ATOM   6494  H HB2    . TYR A 1 414 ? -10.019 -26.758 -24.372 1.00 20.85  ? 414 TYR A HB2    1 
ATOM   6495  H HB3    . TYR A 1 414 ? -11.341 -27.573 -24.056 1.00 20.85  ? 414 TYR A HB3    1 
ATOM   6496  H HD1    . TYR A 1 414 ? -13.442 -26.585 -25.409 1.00 21.90  ? 414 TYR A HD1    1 
ATOM   6497  H HD2    . TYR A 1 414 ? -9.646  -26.374 -26.624 1.00 26.13  ? 414 TYR A HD2    1 
ATOM   6498  H HE1    . TYR A 1 414 ? -14.160 -26.289 -27.584 1.00 21.78  ? 414 TYR A HE1    1 
ATOM   6499  H HE2    . TYR A 1 414 ? -10.355 -26.077 -28.798 1.00 25.11  ? 414 TYR A HE2    1 
ATOM   6500  H HH     . TYR A 1 414 ? -12.082 -25.900 -30.210 1.00 23.20  ? 414 TYR A HH     1 
ATOM   6501  N N      . ALA A 1 415 ? -10.043 -25.966 -21.347 1.00 19.11  ? 415 ALA A N      1 
ATOM   6502  C CA     . ALA A 1 415 ? -9.804  -26.423 -19.979 1.00 20.75  ? 415 ALA A CA     1 
ATOM   6503  C C      . ALA A 1 415 ? -10.743 -25.699 -19.004 1.00 19.98  ? 415 ALA A C      1 
ATOM   6504  O O      . ALA A 1 415 ? -11.240 -26.299 -18.045 1.00 17.92  ? 415 ALA A O      1 
ATOM   6505  C CB     . ALA A 1 415 ? -8.353  -26.206 -19.579 1.00 22.35  ? 415 ALA A CB     1 
ATOM   6506  H H      . ALA A 1 415 ? -9.380  -25.557 -21.711 1.00 22.93  ? 415 ALA A H      1 
ATOM   6507  H HA     . ALA A 1 415 ? -9.991  -27.373 -19.926 1.00 24.90  ? 415 ALA A HA     1 
ATOM   6508  H HB1    . ALA A 1 415 ? -8.224  -26.532 -18.675 1.00 26.82  ? 415 ALA A HB1    1 
ATOM   6509  H HB2    . ALA A 1 415 ? -7.781  -26.693 -20.192 1.00 26.82  ? 415 ALA A HB2    1 
ATOM   6510  H HB3    . ALA A 1 415 ? -8.152  -25.258 -19.621 1.00 26.82  ? 415 ALA A HB3    1 
ATOM   6511  N N      . HIS A 1 416 ? -10.972 -24.410 -19.243 1.00 17.05  ? 416 HIS A N      1 
ATOM   6512  C CA     . HIS A 1 416 ? -11.914 -23.646 -18.437 1.00 17.45  ? 416 HIS A CA     1 
ATOM   6513  C C      . HIS A 1 416 ? -13.326 -24.181 -18.651 1.00 18.21  ? 416 HIS A C      1 
ATOM   6514  O O      . HIS A 1 416 ? -14.088 -24.298 -17.701 1.00 16.39  ? 416 HIS A O      1 
ATOM   6515  C CB     . HIS A 1 416 ? -11.864 -22.150 -18.777 1.00 17.02  ? 416 HIS A CB     1 
ATOM   6516  C CG     . HIS A 1 416 ? -10.569 -21.484 -18.410 1.00 17.99  ? 416 HIS A CG     1 
ATOM   6517  N ND1    . HIS A 1 416 ? -9.859  -20.709 -19.301 1.00 18.88  ? 416 HIS A ND1    1 
ATOM   6518  C CD2    . HIS A 1 416 ? -9.859  -21.474 -17.254 1.00 18.94  ? 416 HIS A CD2    1 
ATOM   6519  C CE1    . HIS A 1 416 ? -8.767  -20.247 -18.714 1.00 18.69  ? 416 HIS A CE1    1 
ATOM   6520  N NE2    . HIS A 1 416 ? -8.745  -20.694 -17.470 1.00 20.99  ? 416 HIS A NE2    1 
ATOM   6521  H H      . HIS A 1 416 ? -10.593 -23.956 -19.867 1.00 20.46  ? 416 HIS A H      1 
ATOM   6522  H HA     . HIS A 1 416 ? -11.689 -23.751 -17.499 1.00 20.95  ? 416 HIS A HA     1 
ATOM   6523  H HB2    . HIS A 1 416 ? -11.992 -22.043 -19.732 1.00 20.42  ? 416 HIS A HB2    1 
ATOM   6524  H HB3    . HIS A 1 416 ? -12.576 -21.697 -18.298 1.00 20.42  ? 416 HIS A HB3    1 
ATOM   6525  H HD2    . HIS A 1 416 ? -10.085 -21.908 -16.463 1.00 22.73  ? 416 HIS A HD2    1 
ATOM   6526  H HE1    . HIS A 1 416 ? -8.126  -19.700 -19.108 1.00 22.43  ? 416 HIS A HE1    1 
ATOM   6527  H HE2    . HIS A 1 416 ? -8.131  -20.530 -16.891 1.00 25.18  ? 416 HIS A HE2    1 
ATOM   6528  N N      . MET A 1 417 ? -13.673 -24.508 -19.894 1.00 17.26  ? 417 MET A N      1 
ATOM   6529  C CA     . MET A 1 417 ? -14.987 -25.086 -20.169 1.00 17.44  ? 417 MET A CA     1 
ATOM   6530  C C      . MET A 1 417 ? -15.155 -26.425 -19.430 1.00 17.10  ? 417 MET A C      1 
ATOM   6531  O O      . MET A 1 417 ? -16.223 -26.701 -18.895 1.00 16.31  ? 417 MET A O      1 
ATOM   6532  C CB     . MET A 1 417 ? -15.202 -25.289 -21.671 1.00 16.83  ? 417 MET A CB     1 
ATOM   6533  C CG     . MET A 1 417 ? -15.208 -24.009 -22.513 1.00 16.76  ? 417 MET A CG     1 
ATOM   6534  S SD     . MET A 1 417 ? -16.428 -22.764 -22.045 1.00 19.79  ? 417 MET A SD     1 
ATOM   6535  C CE     . MET A 1 417 ? -15.412 -21.685 -21.013 1.00 21.82  ? 417 MET A CE     1 
ATOM   6536  H H      . MET A 1 417 ? -13.174 -24.407 -20.587 1.00 20.71  ? 417 MET A H      1 
ATOM   6537  H HA     . MET A 1 417 ? -15.668 -24.471 -19.854 1.00 20.93  ? 417 MET A HA     1 
ATOM   6538  H HB2    . MET A 1 417 ? -14.492 -25.856 -22.009 1.00 20.20  ? 417 MET A HB2    1 
ATOM   6539  H HB3    . MET A 1 417 ? -16.057 -25.728 -21.802 1.00 20.20  ? 417 MET A HB3    1 
ATOM   6540  H HG2    . MET A 1 417 ? -14.334 -23.595 -22.448 1.00 20.11  ? 417 MET A HG2    1 
ATOM   6541  H HG3    . MET A 1 417 ? -15.382 -24.252 -23.436 1.00 20.11  ? 417 MET A HG3    1 
ATOM   6542  H HE1    . MET A 1 417 ? -15.959 -20.953 -20.688 1.00 26.18  ? 417 MET A HE1    1 
ATOM   6543  H HE2    . MET A 1 417 ? -15.067 -22.197 -20.265 1.00 26.18  ? 417 MET A HE2    1 
ATOM   6544  H HE3    . MET A 1 417 ? -14.678 -21.340 -21.545 1.00 26.18  ? 417 MET A HE3    1 
ATOM   6545  N N      . ASP A 1 418 ? -14.098 -27.238 -19.389 1.00 16.65  ? 418 ASP A N      1 
ATOM   6546  C CA     . ASP A 1 418 ? -14.116 -28.509 -18.658 1.00 18.91  ? 418 ASP A CA     1 
ATOM   6547  C C      . ASP A 1 418 ? -14.332 -28.292 -17.170 1.00 20.49  ? 418 ASP A C      1 
ATOM   6548  O O      . ASP A 1 418 ? -15.070 -29.026 -16.517 1.00 19.42  ? 418 ASP A O      1 
ATOM   6549  C CB     . ASP A 1 418 ? -12.807 -29.279 -18.860 1.00 19.57  ? 418 ASP A CB     1 
ATOM   6550  C CG     . ASP A 1 418 ? -12.722 -29.953 -20.213 1.00 23.95  ? 418 ASP A CG     1 
ATOM   6551  O OD1    . ASP A 1 418 ? -13.773 -30.216 -20.814 1.00 25.39  ? 418 ASP A OD1    1 
ATOM   6552  O OD2    . ASP A 1 418 ? -11.596 -30.238 -20.666 1.00 24.97  ? 418 ASP A OD2    1 
ATOM   6553  H H      . ASP A 1 418 ? -13.350 -27.075 -19.781 1.00 19.98  ? 418 ASP A H      1 
ATOM   6554  H HA     . ASP A 1 418 ? -14.850 -29.053 -18.984 1.00 22.70  ? 418 ASP A HA     1 
ATOM   6555  H HB2    . ASP A 1 418 ? -12.063 -28.662 -18.786 1.00 23.48  ? 418 ASP A HB2    1 
ATOM   6556  H HB3    . ASP A 1 418 ? -12.737 -29.966 -18.179 1.00 23.48  ? 418 ASP A HB3    1 
ATOM   6557  N N      . LEU A 1 419 ? -13.678 -27.273 -16.632 1.00 20.57  ? 419 LEU A N      1 
ATOM   6558  C CA     . LEU A 1 419 ? -13.789 -26.976 -15.221 1.00 22.67  ? 419 LEU A CA     1 
ATOM   6559  C C      . LEU A 1 419 ? -15.227 -26.583 -14.889 1.00 19.23  ? 419 LEU A C      1 
ATOM   6560  O O      . LEU A 1 419 ? -15.796 -27.052 -13.898 1.00 20.03  ? 419 LEU A O      1 
ATOM   6561  C CB     . LEU A 1 419 ? -12.808 -25.872 -14.853 1.00 24.37  ? 419 LEU A CB     1 
ATOM   6562  C CG     . LEU A 1 419 ? -12.835 -25.373 -13.415 1.00 29.32  ? 419 LEU A CG     1 
ATOM   6563  C CD1    . LEU A 1 419 ? -11.419 -25.136 -12.928 1.00 32.38  ? 419 LEU A CD1    1 
ATOM   6564  C CD2    . LEU A 1 419 ? -13.632 -24.112 -13.350 1.00 25.98  ? 419 LEU A CD2    1 
ATOM   6565  H H      . LEU A 1 419 ? -13.163 -26.739 -17.067 1.00 24.69  ? 419 LEU A H      1 
ATOM   6566  H HA     . LEU A 1 419 ? -13.563 -27.768 -14.708 1.00 27.21  ? 419 LEU A HA     1 
ATOM   6567  H HB2    . LEU A 1 419 ? -11.911 -26.197 -15.026 1.00 29.25  ? 419 LEU A HB2    1 
ATOM   6568  H HB3    . LEU A 1 419 ? -12.986 -25.109 -15.425 1.00 29.25  ? 419 LEU A HB3    1 
ATOM   6569  H HG     . LEU A 1 419 ? -13.254 -26.037 -12.845 1.00 35.18  ? 419 LEU A HG     1 
ATOM   6570  H HD11   . LEU A 1 419 ? -11.452 -24.766 -12.032 1.00 38.85  ? 419 LEU A HD11   1 
ATOM   6571  H HD12   . LEU A 1 419 ? -10.942 -25.981 -12.920 1.00 38.85  ? 419 LEU A HD12   1 
ATOM   6572  H HD13   . LEU A 1 419 ? -10.980 -24.513 -13.528 1.00 38.85  ? 419 LEU A HD13   1 
ATOM   6573  H HD21   . LEU A 1 419 ? -13.676 -23.816 -12.427 1.00 31.18  ? 419 LEU A HD21   1 
ATOM   6574  H HD22   . LEU A 1 419 ? -13.198 -23.436 -13.893 1.00 31.18  ? 419 LEU A HD22   1 
ATOM   6575  H HD23   . LEU A 1 419 ? -14.526 -24.282 -13.685 1.00 31.18  ? 419 LEU A HD23   1 
ATOM   6576  N N      . VAL A 1 420 ? -15.811 -25.746 -15.744 1.00 17.28  ? 420 VAL A N      1 
ATOM   6577  C CA     . VAL A 1 420 ? -17.203 -25.324 -15.623 1.00 16.19  ? 420 VAL A CA     1 
ATOM   6578  C C      . VAL A 1 420 ? -18.129 -26.543 -15.685 1.00 18.89  ? 420 VAL A C      1 
ATOM   6579  O O      . VAL A 1 420 ? -18.942 -26.775 -14.776 1.00 18.74  ? 420 VAL A O      1 
ATOM   6580  C CB     . VAL A 1 420 ? -17.602 -24.318 -16.743 1.00 14.90  ? 420 VAL A CB     1 
ATOM   6581  C CG1    . VAL A 1 420 ? -19.085 -24.004 -16.704 1.00 17.09  ? 420 VAL A CG1    1 
ATOM   6582  C CG2    . VAL A 1 420 ? -16.801 -23.028 -16.633 1.00 20.72  ? 420 VAL A CG2    1 
ATOM   6583  H H      . VAL A 1 420 ? -15.409 -25.400 -16.421 1.00 20.73  ? 420 VAL A H      1 
ATOM   6584  H HA     . VAL A 1 420 ? -17.331 -24.889 -14.765 1.00 19.43  ? 420 VAL A HA     1 
ATOM   6585  H HB     . VAL A 1 420 ? -17.406 -24.716 -17.605 1.00 17.88  ? 420 VAL A HB     1 
ATOM   6586  H HG11   . VAL A 1 420 ? -19.249 -23.201 -17.223 1.00 20.51  ? 420 VAL A HG11   1 
ATOM   6587  H HG12   . VAL A 1 420 ? -19.579 -24.748 -17.083 1.00 20.51  ? 420 VAL A HG12   1 
ATOM   6588  H HG13   . VAL A 1 420 ? -19.353 -23.861 -15.783 1.00 20.51  ? 420 VAL A HG13   1 
ATOM   6589  H HG21   . VAL A 1 420 ? -16.791 -22.589 -17.498 1.00 24.86  ? 420 VAL A HG21   1 
ATOM   6590  H HG22   . VAL A 1 420 ? -17.221 -22.452 -15.975 1.00 24.86  ? 420 VAL A HG22   1 
ATOM   6591  H HG23   . VAL A 1 420 ? -15.895 -23.237 -16.359 1.00 24.86  ? 420 VAL A HG23   1 
ATOM   6592  N N      . ALA A 1 421 ? -17.998 -27.319 -16.754 1.00 18.43  ? 421 ALA A N      1 
ATOM   6593  C CA     . ALA A 1 421 ? -18.854 -28.485 -16.949 1.00 18.29  ? 421 ALA A CA     1 
ATOM   6594  C C      . ALA A 1 421 ? -18.680 -29.517 -15.828 1.00 18.22  ? 421 ALA A C      1 
ATOM   6595  O O      . ALA A 1 421 ? -19.665 -30.060 -15.330 1.00 18.32  ? 421 ALA A O      1 
ATOM   6596  C CB     . ALA A 1 421 ? -18.574 -29.118 -18.295 1.00 21.15  ? 421 ALA A CB     1 
ATOM   6597  H H      . ALA A 1 421 ? -17.423 -27.194 -17.381 1.00 22.12  ? 421 ALA A H      1 
ATOM   6598  H HA     . ALA A 1 421 ? -19.780 -28.196 -16.944 1.00 21.95  ? 421 ALA A HA     1 
ATOM   6599  H HB1    . ALA A 1 421 ? -19.151 -29.890 -18.407 1.00 25.38  ? 421 ALA A HB1    1 
ATOM   6600  H HB2    . ALA A 1 421 ? -18.752 -28.468 -18.992 1.00 25.38  ? 421 ALA A HB2    1 
ATOM   6601  H HB3    . ALA A 1 421 ? -17.644 -29.392 -18.327 1.00 25.38  ? 421 ALA A HB3    1 
ATOM   6602  N N      . ASP A 1 422 ? -17.436 -29.804 -15.439 1.00 18.53  ? 422 ASP A N      1 
ATOM   6603  C CA     . ASP A 1 422 ? -17.183 -30.813 -14.406 1.00 23.89  ? 422 ASP A CA     1 
ATOM   6604  C C      . ASP A 1 422 ? -17.824 -30.424 -13.074 1.00 22.27  ? 422 ASP A C      1 
ATOM   6605  O O      . ASP A 1 422 ? -18.352 -31.274 -12.347 1.00 21.01  ? 422 ASP A O      1 
ATOM   6606  C CB     . ASP A 1 422 ? -15.682 -31.026 -14.199 1.00 21.10  ? 422 ASP A CB     1 
ATOM   6607  C CG     . ASP A 1 422 ? -15.029 -31.800 -15.329 1.00 30.48  ? 422 ASP A CG     1 
ATOM   6608  O OD1    . ASP A 1 422 ? -15.747 -32.334 -16.203 1.00 28.05  ? 422 ASP A OD1    1 
ATOM   6609  O OD2    . ASP A 1 422 ? -13.779 -31.874 -15.334 1.00 37.12  ? 422 ASP A OD2    1 
ATOM   6610  H H      . ASP A 1 422 ? -16.727 -29.433 -15.754 1.00 22.24  ? 422 ASP A H      1 
ATOM   6611  H HA     . ASP A 1 422 ? -17.574 -31.655 -14.685 1.00 28.67  ? 422 ASP A HA     1 
ATOM   6612  H HB2    . ASP A 1 422 ? -15.247 -30.161 -14.138 1.00 25.32  ? 422 ASP A HB2    1 
ATOM   6613  H HB3    . ASP A 1 422 ? -15.545 -31.524 -13.378 1.00 25.32  ? 422 ASP A HB3    1 
ATOM   6614  N N      . GLY A 1 423 ? -17.783 -29.140 -12.751 1.00 21.67  ? 423 GLY A N      1 
ATOM   6615  C CA     . GLY A 1 423 ? -18.395 -28.655 -11.531 1.00 21.04  ? 423 GLY A CA     1 
ATOM   6616  C C      . GLY A 1 423 ? -19.910 -28.762 -11.564 1.00 20.74  ? 423 GLY A C      1 
ATOM   6617  O O      . GLY A 1 423 ? -20.532 -29.207 -10.601 1.00 19.85  ? 423 GLY A O      1 
ATOM   6618  H H      . GLY A 1 423 ? -17.405 -28.529 -13.224 1.00 26.01  ? 423 GLY A H      1 
ATOM   6619  H HA2    . GLY A 1 423 ? -18.068 -29.169 -10.777 1.00 25.25  ? 423 GLY A HA2    1 
ATOM   6620  H HA3    . GLY A 1 423 ? -18.156 -27.725 -11.397 1.00 25.25  ? 423 GLY A HA3    1 
ATOM   6621  N N      . ILE A 1 424 ? -20.512 -28.360 -12.675 1.00 17.49  ? 424 ILE A N      1 
ATOM   6622  C CA     . ILE A 1 424 ? -21.965 -28.450 -12.828 1.00 18.35  ? 424 ILE A CA     1 
ATOM   6623  C C      . ILE A 1 424 ? -22.427 -29.914 -12.787 1.00 22.30  ? 424 ILE A C      1 
ATOM   6624  O O      . ILE A 1 424 ? -23.453 -30.246 -12.185 1.00 21.66  ? 424 ILE A O      1 
ATOM   6625  C CB     . ILE A 1 424 ? -22.417 -27.795 -14.150 1.00 17.50  ? 424 ILE A CB     1 
ATOM   6626  C CG1    . ILE A 1 424 ? -22.138 -26.290 -14.093 1.00 19.70  ? 424 ILE A CG1    1 
ATOM   6627  C CG2    . ILE A 1 424 ? -23.909 -28.078 -14.438 1.00 18.76  ? 424 ILE A CG2    1 
ATOM   6628  C CD1    . ILE A 1 424 ? -22.273 -25.585 -15.427 1.00 21.34  ? 424 ILE A CD1    1 
ATOM   6629  H H      . ILE A 1 424 ? -20.105 -28.031 -13.358 1.00 20.99  ? 424 ILE A H      1 
ATOM   6630  H HA     . ILE A 1 424 ? -22.392 -27.978 -12.096 1.00 22.02  ? 424 ILE A HA     1 
ATOM   6631  H HB     . ILE A 1 424 ? -21.892 -28.174 -14.872 1.00 20.99  ? 424 ILE A HB     1 
ATOM   6632  H HG12   . ILE A 1 424 ? -22.767 -25.881 -13.479 1.00 23.64  ? 424 ILE A HG12   1 
ATOM   6633  H HG13   . ILE A 1 424 ? -21.233 -26.149 -13.776 1.00 23.64  ? 424 ILE A HG13   1 
ATOM   6634  H HG21   . ILE A 1 424 ? -24.219 -27.478 -15.133 1.00 22.52  ? 424 ILE A HG21   1 
ATOM   6635  H HG22   . ILE A 1 424 ? -24.008 -28.997 -14.732 1.00 22.52  ? 424 ILE A HG22   1 
ATOM   6636  H HG23   . ILE A 1 424 ? -24.419 -27.932 -13.626 1.00 22.52  ? 424 ILE A HG23   1 
ATOM   6637  H HD11   . ILE A 1 424 ? -21.970 -24.669 -15.330 1.00 25.60  ? 424 ILE A HD11   1 
ATOM   6638  H HD12   . ILE A 1 424 ? -21.727 -26.046 -16.083 1.00 25.60  ? 424 ILE A HD12   1 
ATOM   6639  H HD13   . ILE A 1 424 ? -23.202 -25.599 -15.702 1.00 25.60  ? 424 ILE A HD13   1 
ATOM   6640  N N      . ILE A 1 425 ? -21.660 -30.784 -13.427 1.00 19.72  ? 425 ILE A N      1 
ATOM   6641  C CA     . ILE A 1 425 ? -21.996 -32.204 -13.480 1.00 21.12  ? 425 ILE A CA     1 
ATOM   6642  C C      . ILE A 1 425 ? -21.920 -32.825 -12.083 1.00 25.18  ? 425 ILE A C      1 
ATOM   6643  O O      . ILE A 1 425 ? -22.774 -33.624 -11.710 1.00 22.23  ? 425 ILE A O      1 
ATOM   6644  C CB     . ILE A 1 425 ? -21.076 -32.934 -14.466 1.00 20.71  ? 425 ILE A CB     1 
ATOM   6645  C CG1    . ILE A 1 425 ? -21.477 -32.550 -15.896 1.00 19.58  ? 425 ILE A CG1    1 
ATOM   6646  C CG2    . ILE A 1 425 ? -21.145 -34.469 -14.300 1.00 24.07  ? 425 ILE A CG2    1 
ATOM   6647  C CD1    . ILE A 1 425 ? -20.437 -32.906 -16.942 1.00 23.77  ? 425 ILE A CD1    1 
ATOM   6648  H H      . ILE A 1 425 ? -20.935 -30.579 -13.842 1.00 23.66  ? 425 ILE A H      1 
ATOM   6649  H HA     . ILE A 1 425 ? -22.907 -32.299 -13.798 1.00 25.35  ? 425 ILE A HA     1 
ATOM   6650  H HB     . ILE A 1 425 ? -20.163 -32.645 -14.311 1.00 24.85  ? 425 ILE A HB     1 
ATOM   6651  H HG12   . ILE A 1 425 ? -22.297 -33.015 -16.125 1.00 23.49  ? 425 ILE A HG12   1 
ATOM   6652  H HG13   . ILE A 1 425 ? -21.623 -31.592 -15.935 1.00 23.49  ? 425 ILE A HG13   1 
ATOM   6653  H HG21   . ILE A 1 425 ? -20.740 -34.891 -15.073 1.00 28.88  ? 425 ILE A HG21   1 
ATOM   6654  H HG22   . ILE A 1 425 ? -20.663 -34.724 -13.498 1.00 28.88  ? 425 ILE A HG22   1 
ATOM   6655  H HG23   . ILE A 1 425 ? -22.075 -34.737 -14.229 1.00 28.88  ? 425 ILE A HG23   1 
ATOM   6656  H HD11   . ILE A 1 425 ? -20.691 -32.505 -17.788 1.00 28.53  ? 425 ILE A HD11   1 
ATOM   6657  H HD12   . ILE A 1 425 ? -19.575 -32.562 -16.659 1.00 28.53  ? 425 ILE A HD12   1 
ATOM   6658  H HD13   . ILE A 1 425 ? -20.394 -33.871 -17.033 1.00 28.53  ? 425 ILE A HD13   1 
ATOM   6659  N N      . LYS A 1 426 ? -20.909 -32.450 -11.309 1.00 22.18  ? 426 LYS A N      1 
ATOM   6660  C CA     . LYS A 1 426 ? -20.814 -32.917 -9.930  1.00 22.66  ? 426 LYS A CA     1 
ATOM   6661  C C      . LYS A 1 426 ? -22.019 -32.440 -9.112  1.00 25.35  ? 426 LYS A C      1 
ATOM   6662  O O      . LYS A 1 426 ? -22.574 -33.195 -8.307  1.00 22.75  ? 426 LYS A O      1 
ATOM   6663  C CB     . LYS A 1 426 ? -19.514 -32.442 -9.286  1.00 26.71  ? 426 LYS A CB     1 
ATOM   6664  C CG     . LYS A 1 426 ? -19.343 -32.915 -7.847  1.00 33.65  ? 426 LYS A CG     1 
ATOM   6665  C CD     . LYS A 1 426 ? -18.107 -32.322 -7.208  1.00 45.49  ? 426 LYS A CD     1 
ATOM   6666  C CE     . LYS A 1 426 ? -17.993 -32.745 -5.749  1.00 51.84  ? 426 LYS A CE     1 
ATOM   6667  N NZ     . LYS A 1 426 ? -17.091 -31.843 -4.986  1.00 52.91  ? 426 LYS A NZ     1 
ATOM   6668  H H      . LYS A 1 426 ? -20.269 -31.930 -11.554 1.00 26.62  ? 426 LYS A H      1 
ATOM   6669  H HA     . LYS A 1 426 ? -20.814 -33.887 -9.925  1.00 27.19  ? 426 LYS A HA     1 
ATOM   6670  H HB2    . LYS A 1 426 ? -18.766 -32.781 -9.802  1.00 32.05  ? 426 LYS A HB2    1 
ATOM   6671  H HB3    . LYS A 1 426 ? -19.501 -31.472 -9.284  1.00 32.05  ? 426 LYS A HB3    1 
ATOM   6672  H HG2    . LYS A 1 426 ? -20.110 -32.642 -7.320  1.00 40.38  ? 426 LYS A HG2    1 
ATOM   6673  H HG3    . LYS A 1 426 ? -19.256 -33.881 -7.837  1.00 40.38  ? 426 LYS A HG3    1 
ATOM   6674  H HD2    . LYS A 1 426 ? -17.319 -32.634 -7.680  1.00 54.59  ? 426 LYS A HD2    1 
ATOM   6675  H HD3    . LYS A 1 426 ? -18.160 -31.354 -7.243  1.00 54.59  ? 426 LYS A HD3    1 
ATOM   6676  H HE2    . LYS A 1 426 ? -18.871 -32.715 -5.338  1.00 62.21  ? 426 LYS A HE2    1 
ATOM   6677  H HE3    . LYS A 1 426 ? -17.632 -33.644 -5.704  1.00 62.21  ? 426 LYS A HE3    1 
ATOM   6678  H HZ1    . LYS A 1 426 ? -17.040 -32.110 -4.138  1.00 63.49  ? 426 LYS A HZ1    1 
ATOM   6679  H HZ2    . LYS A 1 426 ? -16.276 -31.856 -5.342  1.00 63.49  ? 426 LYS A HZ2    1 
ATOM   6680  H HZ3    . LYS A 1 426 ? -17.404 -31.010 -5.009  1.00 63.49  ? 426 LYS A HZ3    1 
ATOM   6681  N N      . LEU A 1 427 ? -22.419 -31.186 -9.302  1.00 21.09  ? 427 LEU A N      1 
ATOM   6682  C CA     . LEU A 1 427 ? -23.603 -30.673 -8.625  1.00 23.26  ? 427 LEU A CA     1 
ATOM   6683  C C      . LEU A 1 427 ? -24.849 -31.432 -9.045  1.00 26.16  ? 427 LEU A C      1 
ATOM   6684  O O      . LEU A 1 427 ? -25.736 -31.681 -8.229  1.00 24.93  ? 427 LEU A O      1 
ATOM   6685  C CB     . LEU A 1 427 ? -23.793 -29.188 -8.912  1.00 21.28  ? 427 LEU A CB     1 
ATOM   6686  C CG     . LEU A 1 427 ? -22.855 -28.260 -8.147  1.00 23.95  ? 427 LEU A CG     1 
ATOM   6687  C CD1    . LEU A 1 427 ? -22.970 -26.875 -8.717  1.00 21.94  ? 427 LEU A CD1    1 
ATOM   6688  C CD2    . LEU A 1 427 ? -23.184 -28.265 -6.653  1.00 22.94  ? 427 LEU A CD2    1 
ATOM   6689  H H      . LEU A 1 427 ? -22.026 -30.617 -9.813  1.00 25.31  ? 427 LEU A H      1 
ATOM   6690  H HA     . LEU A 1 427 ? -23.493 -30.787 -7.668  1.00 27.91  ? 427 LEU A HA     1 
ATOM   6691  H HB2    . LEU A 1 427 ? -23.648 -29.036 -9.859  1.00 25.53  ? 427 LEU A HB2    1 
ATOM   6692  H HB3    . LEU A 1 427 ? -24.702 -28.942 -8.679  1.00 25.53  ? 427 LEU A HB3    1 
ATOM   6693  H HG     . LEU A 1 427 ? -21.940 -28.562 -8.260  1.00 28.74  ? 427 LEU A HG     1 
ATOM   6694  H HD11   . LEU A 1 427 ? -22.384 -26.281 -8.222  1.00 26.33  ? 427 LEU A HD11   1 
ATOM   6695  H HD12   . LEU A 1 427 ? -22.709 -26.895 -9.651  1.00 26.33  ? 427 LEU A HD12   1 
ATOM   6696  H HD13   . LEU A 1 427 ? -23.889 -26.576 -8.636  1.00 26.33  ? 427 LEU A HD13   1 
ATOM   6697  H HD21   . LEU A 1 427 ? -22.683 -27.557 -6.218  1.00 27.53  ? 427 LEU A HD21   1 
ATOM   6698  H HD22   . LEU A 1 427 ? -24.136 -28.115 -6.539  1.00 27.53  ? 427 LEU A HD22   1 
ATOM   6699  H HD23   . LEU A 1 427 ? -22.937 -29.124 -6.276  1.00 27.53  ? 427 LEU A HD23   1 
ATOM   6700  N N      . PHE A 1 428 ? -24.907 -31.802 -10.320 1.00 20.34  ? 428 PHE A N      1 
ATOM   6701  C CA     . PHE A 1 428 ? -26.069 -32.495 -10.869 1.00 24.36  ? 428 PHE A CA     1 
ATOM   6702  C C      . PHE A 1 428 ? -26.217 -33.894 -10.261 1.00 23.47  ? 428 PHE A C      1 
ATOM   6703  O O      . PHE A 1 428 ? -27.330 -34.347 -10.004 1.00 28.06  ? 428 PHE A O      1 
ATOM   6704  C CB     . PHE A 1 428 ? -25.955 -32.581 -12.395 1.00 24.77  ? 428 PHE A CB     1 
ATOM   6705  C CG     . PHE A 1 428 ? -27.170 -33.163 -13.069 1.00 25.92  ? 428 PHE A CG     1 
ATOM   6706  C CD1    . PHE A 1 428 ? -28.395 -32.530 -12.984 1.00 26.07  ? 428 PHE A CD1    1 
ATOM   6707  C CD2    . PHE A 1 428 ? -27.074 -34.331 -13.808 1.00 29.97  ? 428 PHE A CD2    1 
ATOM   6708  C CE1    . PHE A 1 428 ? -29.509 -33.056 -13.606 1.00 29.77  ? 428 PHE A CE1    1 
ATOM   6709  C CE2    . PHE A 1 428 ? -28.181 -34.863 -14.432 1.00 28.47  ? 428 PHE A CE2    1 
ATOM   6710  C CZ     . PHE A 1 428 ? -29.401 -34.224 -14.331 1.00 28.37  ? 428 PHE A CZ     1 
ATOM   6711  H H      . PHE A 1 428 ? -24.281 -31.662 -10.893 1.00 24.41  ? 428 PHE A H      1 
ATOM   6712  H HA     . PHE A 1 428 ? -26.868 -31.989 -10.655 1.00 29.23  ? 428 PHE A HA     1 
ATOM   6713  H HB2    . PHE A 1 428 ? -25.819 -31.688 -12.749 1.00 29.72  ? 428 PHE A HB2    1 
ATOM   6714  H HB3    . PHE A 1 428 ? -25.196 -33.141 -12.620 1.00 29.72  ? 428 PHE A HB3    1 
ATOM   6715  H HD1    . PHE A 1 428 ? -28.472 -31.743 -12.494 1.00 31.29  ? 428 PHE A HD1    1 
ATOM   6716  H HD2    . PHE A 1 428 ? -26.255 -34.766 -13.876 1.00 35.96  ? 428 PHE A HD2    1 
ATOM   6717  H HE1    . PHE A 1 428 ? -30.330 -32.624 -13.537 1.00 35.73  ? 428 PHE A HE1    1 
ATOM   6718  H HE2    . PHE A 1 428 ? -28.107 -35.650 -14.921 1.00 34.17  ? 428 PHE A HE2    1 
ATOM   6719  H HZ     . PHE A 1 428 ? -30.149 -34.581 -14.752 1.00 34.05  ? 428 PHE A HZ     1 
ATOM   6720  N N      . LYS A 1 429 ? -25.094 -34.569 -10.035 1.00 26.50  ? 429 LYS A N      1 
ATOM   6721  C CA     . LYS A 1 429 ? -25.105 -35.915 -9.469  1.00 28.52  ? 429 LYS A CA     1 
ATOM   6722  C C      . LYS A 1 429 ? -25.524 -35.900 -7.999  1.00 32.57  ? 429 LYS A C      1 
ATOM   6723  O O      . LYS A 1 429 ? -25.925 -36.925 -7.454  1.00 32.79  ? 429 LYS A O      1 
ATOM   6724  C CB     . LYS A 1 429 ? -23.723 -36.567 -9.612  1.00 30.34  ? 429 LYS A CB     1 
ATOM   6725  C CG     . LYS A 1 429 ? -23.354 -36.930 -11.043 1.00 32.65  ? 429 LYS A CG     1 
ATOM   6726  C CD     . LYS A 1 429 ? -21.923 -37.435 -11.138 1.00 37.86  ? 429 LYS A CD     1 
ATOM   6727  C CE     . LYS A 1 429 ? -21.532 -37.744 -12.579 1.00 47.13  ? 429 LYS A CE     1 
ATOM   6728  N NZ     . LYS A 1 429 ? -20.074 -38.056 -12.716 1.00 56.60  ? 429 LYS A NZ     1 
ATOM   6729  H H      . LYS A 1 429 ? -24.306 -34.267 -10.202 1.00 31.80  ? 429 LYS A H      1 
ATOM   6730  H HA     . LYS A 1 429 ? -25.744 -36.457 -9.957  1.00 34.22  ? 429 LYS A HA     1 
ATOM   6731  H HB2    . LYS A 1 429 ? -23.052 -35.950 -9.281  1.00 36.41  ? 429 LYS A HB2    1 
ATOM   6732  H HB3    . LYS A 1 429 ? -23.707 -37.382 -9.087  1.00 36.41  ? 429 LYS A HB3    1 
ATOM   6733  H HG2    . LYS A 1 429 ? -23.945 -37.632 -11.358 1.00 39.18  ? 429 LYS A HG2    1 
ATOM   6734  H HG3    . LYS A 1 429 ? -23.437 -36.144 -11.605 1.00 39.18  ? 429 LYS A HG3    1 
ATOM   6735  H HD2    . LYS A 1 429 ? -21.321 -36.755 -10.799 1.00 45.44  ? 429 LYS A HD2    1 
ATOM   6736  H HD3    . LYS A 1 429 ? -21.836 -38.249 -10.618 1.00 45.44  ? 429 LYS A HD3    1 
ATOM   6737  H HE2    . LYS A 1 429 ? -22.035 -38.514 -12.887 1.00 56.56  ? 429 LYS A HE2    1 
ATOM   6738  H HE3    . LYS A 1 429 ? -21.729 -36.973 -13.134 1.00 56.56  ? 429 LYS A HE3    1 
ATOM   6739  H HZ1    . LYS A 1 429 ? -19.588 -37.361 -12.446 1.00 67.92  ? 429 LYS A HZ1    1 
ATOM   6740  H HZ2    . LYS A 1 429 ? -19.867 -38.765 -12.219 1.00 67.92  ? 429 LYS A HZ2    1 
ATOM   6741  H HZ3    . LYS A 1 429 ? -19.879 -38.232 -13.566 1.00 67.92  ? 429 LYS A HZ3    1 
ATOM   6742  N N      . HIS A 1 430 ? -25.427 -34.734 -7.367  1.00 28.17  ? 430 HIS A N      1 
ATOM   6743  C CA     . HIS A 1 430 ? -25.808 -34.568 -5.966  1.00 32.12  ? 430 HIS A CA     1 
ATOM   6744  C C      . HIS A 1 430 ? -26.830 -33.446 -5.833  1.00 32.01  ? 430 HIS A C      1 
ATOM   6745  O O      . HIS A 1 430 ? -26.852 -32.725 -4.830  1.00 29.50  ? 430 HIS A O      1 
ATOM   6746  C CB     . HIS A 1 430 ? -24.579 -34.262 -5.103  1.00 36.37  ? 430 HIS A CB     1 
ATOM   6747  C CG     . HIS A 1 430 ? -23.509 -35.307 -5.178  1.00 46.47  ? 430 HIS A CG     1 
ATOM   6748  N ND1    . HIS A 1 430 ? -22.382 -35.164 -5.958  1.00 50.47  ? 430 HIS A ND1    1 
ATOM   6749  C CD2    . HIS A 1 430 ? -23.396 -36.511 -4.569  1.00 47.20  ? 430 HIS A CD2    1 
ATOM   6750  C CE1    . HIS A 1 430 ? -21.618 -36.236 -5.826  1.00 53.23  ? 430 HIS A CE1    1 
ATOM   6751  N NE2    . HIS A 1 430 ? -22.212 -37.067 -4.989  1.00 52.90  ? 430 HIS A NE2    1 
ATOM   6752  H H      . HIS A 1 430 ? -25.138 -34.011 -7.731  1.00 33.80  ? 430 HIS A H      1 
ATOM   6753  H HA     . HIS A 1 430 ? -26.214 -35.383 -5.633  1.00 38.54  ? 430 HIS A HA     1 
ATOM   6754  H HB2    . HIS A 1 430 ? -24.193 -33.421 -5.395  1.00 43.65  ? 430 HIS A HB2    1 
ATOM   6755  H HB3    . HIS A 1 430 ? -24.857 -34.192 -4.176  1.00 43.65  ? 430 HIS A HB3    1 
ATOM   6756  H HD1    . HIS A 1 430 ? -22.203 -34.484 -6.452  1.00 60.56  ? 430 HIS A HD1    1 
ATOM   6757  H HD2    . HIS A 1 430 ? -24.005 -36.890 -3.977  1.00 56.64  ? 430 HIS A HD2    1 
ATOM   6758  H HE1    . HIS A 1 430 ? -20.803 -36.380 -6.251  1.00 63.88  ? 430 HIS A HE1    1 
ATOM   6759  N N      . LYS A 1 431 ? -27.670 -33.302 -6.854  1.00 27.74  ? 431 LYS A N      1 
ATOM   6760  C CA     . LYS A 1 431 ? -28.551 -32.145 -6.966  1.00 25.31  ? 431 LYS A CA     1 
ATOM   6761  C C      . LYS A 1 431 ? -29.494 -32.000 -5.786  1.00 29.07  ? 431 LYS A C      1 
ATOM   6762  O O      . LYS A 1 431 ? -29.911 -30.894 -5.466  1.00 27.11  ? 431 LYS A O      1 
ATOM   6763  C CB     . LYS A 1 431 ? -29.376 -32.216 -8.248  1.00 28.04  ? 431 LYS A CB     1 
ATOM   6764  C CG     . LYS A 1 431 ? -30.220 -33.483 -8.406  1.00 29.39  ? 431 LYS A CG     1 
ATOM   6765  C CD     . LYS A 1 431 ? -30.844 -33.527 -9.800  1.00 32.52  ? 431 LYS A CD     1 
ATOM   6766  C CE     . LYS A 1 431 ? -31.534 -34.852 -10.089 1.00 38.83  ? 431 LYS A CE     1 
ATOM   6767  N NZ     . LYS A 1 431 ? -32.831 -34.980 -9.381  1.00 56.43  ? 431 LYS A NZ     1 
ATOM   6768  H H      . LYS A 1 431 ? -27.748 -33.865 -7.500  1.00 33.29  ? 431 LYS A H      1 
ATOM   6769  H HA     . LYS A 1 431 ? -28.007 -31.343 -7.008  1.00 30.38  ? 431 LYS A HA     1 
ATOM   6770  H HB2    . LYS A 1 431 ? -29.981 -31.458 -8.268  1.00 33.65  ? 431 LYS A HB2    1 
ATOM   6771  H HB3    . LYS A 1 431 ? -28.772 -32.170 -9.006  1.00 33.65  ? 431 LYS A HB3    1 
ATOM   6772  H HG2    . LYS A 1 431 ? -29.658 -34.266 -8.296  1.00 35.27  ? 431 LYS A HG2    1 
ATOM   6773  H HG3    . LYS A 1 431 ? -30.934 -33.482 -7.749  1.00 35.27  ? 431 LYS A HG3    1 
ATOM   6774  H HD2    . LYS A 1 431 ? -31.510 -32.828 -9.870  1.00 39.03  ? 431 LYS A HD2    1 
ATOM   6775  H HD3    . LYS A 1 431 ? -30.150 -33.396 -10.465 1.00 39.03  ? 431 LYS A HD3    1 
ATOM   6776  H HE2    . LYS A 1 431 ? -31.702 -34.922 -11.042 1.00 46.60  ? 431 LYS A HE2    1 
ATOM   6777  H HE3    . LYS A 1 431 ? -30.962 -35.578 -9.797  1.00 46.60  ? 431 LYS A HE3    1 
ATOM   6778  H HZ1    . LYS A 1 431 ? -32.704 -34.926 -8.502  1.00 67.72  ? 431 LYS A HZ1    1 
ATOM   6779  H HZ2    . LYS A 1 431 ? -33.381 -34.328 -9.635  1.00 67.72  ? 431 LYS A HZ2    1 
ATOM   6780  H HZ3    . LYS A 1 431 ? -33.205 -35.765 -9.571  1.00 67.72  ? 431 LYS A HZ3    1 
ATOM   6781  N N      . GLU A 1 432 ? -29.839 -33.117 -5.154  1.00 32.06  ? 432 GLU A N      1 
ATOM   6782  C CA     . GLU A 1 432 ? -30.784 -33.092 -4.042  1.00 35.80  ? 432 GLU A CA     1 
ATOM   6783  C C      . GLU A 1 432 ? -30.263 -32.227 -2.896  1.00 35.97  ? 432 GLU A C      1 
ATOM   6784  O O      . GLU A 1 432 ? -31.047 -31.710 -2.097  1.00 36.96  ? 432 GLU A O      1 
ATOM   6785  C CB     . GLU A 1 432 ? -31.075 -34.516 -3.539  1.00 35.61  ? 432 GLU A CB     1 
ATOM   6786  C CG     . GLU A 1 432 ? -29.855 -35.293 -3.052  1.00 42.30  ? 432 GLU A CG     1 
ATOM   6787  C CD     . GLU A 1 432 ? -29.121 -36.031 -4.163  1.00 56.28  ? 432 GLU A CD     1 
ATOM   6788  O OE1    . GLU A 1 432 ? -29.512 -35.899 -5.346  1.00 45.84  ? 432 GLU A OE1    1 
ATOM   6789  O OE2    . GLU A 1 432 ? -28.146 -36.747 -3.845  1.00 54.44  ? 432 GLU A OE2    1 
ATOM   6790  H H      . GLU A 1 432 ? -29.544 -33.899 -5.352  1.00 38.47  ? 432 GLU A H      1 
ATOM   6791  H HA     . GLU A 1 432 ? -31.620 -32.708 -4.349  1.00 42.96  ? 432 GLU A HA     1 
ATOM   6792  H HB2    . GLU A 1 432 ? -31.691 -34.453 -2.792  1.00 42.73  ? 432 GLU A HB2    1 
ATOM   6793  H HB3    . GLU A 1 432 ? -31.492 -35.021 -4.254  1.00 42.73  ? 432 GLU A HB3    1 
ATOM   6794  H HG2    . GLU A 1 432 ? -29.228 -34.679 -2.640  1.00 50.75  ? 432 GLU A HG2    1 
ATOM   6795  H HG3    . GLU A 1 432 ? -30.144 -35.951 -2.401  1.00 50.75  ? 432 GLU A HG3    1 
ATOM   6796  N N      . ASP A 1 433 ? -28.942 -32.064 -2.831  1.00 33.97  ? 433 ASP A N      1 
ATOM   6797  C CA     . ASP A 1 433 ? -28.302 -31.308 -1.756  1.00 31.90  ? 433 ASP A CA     1 
ATOM   6798  C C      . ASP A 1 433 ? -28.315 -29.793 -1.981  1.00 34.29  ? 433 ASP A C      1 
ATOM   6799  O O      . ASP A 1 433 ? -27.892 -29.036 -1.106  1.00 35.24  ? 433 ASP A O      1 
ATOM   6800  C CB     . ASP A 1 433 ? -26.856 -31.775 -1.578  1.00 33.13  ? 433 ASP A CB     1 
ATOM   6801  C CG     . ASP A 1 433 ? -26.759 -33.204 -1.084  1.00 40.38  ? 433 ASP A CG     1 
ATOM   6802  O OD1    . ASP A 1 433 ? -27.700 -33.662 -0.401  1.00 44.25  ? 433 ASP A OD1    1 
ATOM   6803  O OD2    . ASP A 1 433 ? -25.739 -33.865 -1.373  1.00 42.45  ? 433 ASP A OD2    1 
ATOM   6804  H H      . ASP A 1 433 ? -28.387 -32.386 -3.403  1.00 40.76  ? 433 ASP A H      1 
ATOM   6805  H HA     . ASP A 1 433 ? -28.775 -31.482 -0.928  1.00 38.28  ? 433 ASP A HA     1 
ATOM   6806  H HB2    . ASP A 1 433 ? -26.399 -31.721 -2.432  1.00 39.76  ? 433 ASP A HB2    1 
ATOM   6807  H HB3    . ASP A 1 433 ? -26.417 -31.203 -0.929  1.00 39.76  ? 433 ASP A HB3    1 
ATOM   6808  N N      . ILE A 1 434 ? -28.781 -29.353 -3.147  1.00 29.86  ? 434 ILE A N      1 
ATOM   6809  C CA     . ILE A 1 434 ? -28.938 -27.927 -3.417  1.00 33.03  ? 434 ILE A CA     1 
ATOM   6810  C C      . ILE A 1 434 ? -30.132 -27.385 -2.628  1.00 36.08  ? 434 ILE A C      1 
ATOM   6811  O O      . ILE A 1 434 ? -31.262 -27.820 -2.825  1.00 27.36  ? 434 ILE A O      1 
ATOM   6812  C CB     . ILE A 1 434 ? -29.125 -27.651 -4.935  1.00 30.87  ? 434 ILE A CB     1 
ATOM   6813  C CG1    . ILE A 1 434 ? -27.843 -28.014 -5.693  1.00 33.69  ? 434 ILE A CG1    1 
ATOM   6814  C CG2    . ILE A 1 434 ? -29.488 -26.194 -5.187  1.00 30.56  ? 434 ILE A CG2    1 
ATOM   6815  C CD1    . ILE A 1 434 ? -27.996 -28.033 -7.217  1.00 27.40  ? 434 ILE A CD1    1 
ATOM   6816  H H      . ILE A 1 434 ? -29.014 -29.860 -3.801  1.00 35.83  ? 434 ILE A H      1 
ATOM   6817  H HA     . ILE A 1 434 ? -28.142 -27.457 -3.122  1.00 39.64  ? 434 ILE A HA     1 
ATOM   6818  H HB     . ILE A 1 434 ? -29.847 -28.210 -5.264  1.00 37.04  ? 434 ILE A HB     1 
ATOM   6819  H HG12   . ILE A 1 434 ? -27.158 -27.364 -5.474  1.00 40.42  ? 434 ILE A HG12   1 
ATOM   6820  H HG13   . ILE A 1 434 ? -27.556 -28.898 -5.415  1.00 40.42  ? 434 ILE A HG13   1 
ATOM   6821  H HG21   . ILE A 1 434 ? -29.397 -26.001 -6.132  1.00 36.68  ? 434 ILE A HG21   1 
ATOM   6822  H HG22   . ILE A 1 434 ? -30.405 -26.042 -4.911  1.00 36.68  ? 434 ILE A HG22   1 
ATOM   6823  H HG23   . ILE A 1 434 ? -28.889 -25.628 -4.676  1.00 36.68  ? 434 ILE A HG23   1 
ATOM   6824  H HD11   . ILE A 1 434 ? -27.213 -28.452 -7.607  1.00 32.89  ? 434 ILE A HD11   1 
ATOM   6825  H HD12   . ILE A 1 434 ? -28.791 -28.539 -7.447  1.00 32.89  ? 434 ILE A HD12   1 
ATOM   6826  H HD13   . ILE A 1 434 ? -28.079 -27.122 -7.540  1.00 32.89  ? 434 ILE A HD13   1 
ATOM   6827  N N      . LYS A 1 435 ? -29.872 -26.435 -1.732  1.00 31.80  ? 435 LYS A N      1 
ATOM   6828  C CA     . LYS A 1 435 ? -30.913 -25.907 -0.849  1.00 30.55  ? 435 LYS A CA     1 
ATOM   6829  C C      . LYS A 1 435 ? -31.651 -24.726 -1.466  1.00 30.67  ? 435 LYS A C      1 
ATOM   6830  O O      . LYS A 1 435 ? -31.080 -23.960 -2.243  1.00 31.90  ? 435 LYS A O      1 
ATOM   6831  C CB     . LYS A 1 435 ? -30.305 -25.488 0.491   1.00 35.05  ? 435 LYS A CB     1 
ATOM   6832  C CG     . LYS A 1 435 ? -29.666 -26.620 1.277   1.00 41.47  ? 435 LYS A CG     1 
ATOM   6833  C CD     . LYS A 1 435 ? -29.159 -26.131 2.634   1.00 48.13  ? 435 LYS A CD     1 
ATOM   6834  C CE     . LYS A 1 435 ? -28.263 -27.165 3.315   1.00 76.51  ? 435 LYS A CE     1 
ATOM   6835  N NZ     . LYS A 1 435 ? -28.985 -28.423 3.671   1.00 87.91  ? 435 LYS A NZ     1 
ATOM   6836  H H      . LYS A 1 435 ? -29.099 -26.078 -1.614  1.00 38.16  ? 435 LYS A H      1 
ATOM   6837  H HA     . LYS A 1 435 ? -31.563 -26.604 -0.672  1.00 36.66  ? 435 LYS A HA     1 
ATOM   6838  H HB2    . LYS A 1 435 ? -29.617 -24.827 0.323   1.00 42.06  ? 435 LYS A HB2    1 
ATOM   6839  H HB3    . LYS A 1 435 ? -31.003 -25.102 1.043   1.00 42.06  ? 435 LYS A HB3    1 
ATOM   6840  H HG2    . LYS A 1 435 ? -30.324 -27.316 1.430   1.00 49.77  ? 435 LYS A HG2    1 
ATOM   6841  H HG3    . LYS A 1 435 ? -28.912 -26.972 0.778   1.00 49.77  ? 435 LYS A HG3    1 
ATOM   6842  H HD2    . LYS A 1 435 ? -28.643 -25.320 2.508   1.00 57.76  ? 435 LYS A HD2    1 
ATOM   6843  H HD3    . LYS A 1 435 ? -29.917 -25.958 3.214   1.00 57.76  ? 435 LYS A HD3    1 
ATOM   6844  H HE2    . LYS A 1 435 ? -27.537 -27.397 2.715   1.00 91.81  ? 435 LYS A HE2    1 
ATOM   6845  H HE3    . LYS A 1 435 ? -27.907 -26.783 4.133   1.00 91.81  ? 435 LYS A HE3    1 
ATOM   6846  H HZ1    . LYS A 1 435 ? -28.426 -28.994 4.064   1.00 105.50 ? 435 LYS A HZ1    1 
ATOM   6847  H HZ2    . LYS A 1 435 ? -29.653 -28.242 4.230   1.00 105.50 ? 435 LYS A HZ2    1 
ATOM   6848  H HZ3    . LYS A 1 435 ? -29.316 -28.801 2.937   1.00 105.50 ? 435 LYS A HZ3    1 
ATOM   6849  N N      . GLY A 1 436 ? -32.923 -24.574 -1.114  1.00 28.10  ? 436 GLY A N      1 
ATOM   6850  C CA     . GLY A 1 436 ? -33.708 -23.446 -1.580  1.00 27.67  ? 436 GLY A CA     1 
ATOM   6851  C C      . GLY A 1 436 ? -33.269 -22.153 -0.914  1.00 27.99  ? 436 GLY A C      1 
ATOM   6852  O O      . GLY A 1 436 ? -32.669 -22.181 0.163   1.00 30.90  ? 436 GLY A O      1 
ATOM   6853  H H      . GLY A 1 436 ? -33.354 -25.115 -0.603  1.00 33.72  ? 436 GLY A H      1 
ATOM   6854  H HA2    . GLY A 1 436 ? -33.608 -23.351 -2.540  1.00 33.20  ? 436 GLY A HA2    1 
ATOM   6855  H HA3    . GLY A 1 436 ? -34.645 -23.596 -1.378  1.00 33.20  ? 436 GLY A HA3    1 
ATOM   6856  N N      . LEU A 1 437 ? -33.563 -21.024 -1.556  1.00 31.29  ? 437 LEU A N      1 
ATOM   6857  C CA     . LEU A 1 437 ? -33.215 -19.706 -1.015  1.00 32.00  ? 437 LEU A CA     1 
ATOM   6858  C C      . LEU A 1 437 ? -34.459 -18.909 -0.658  1.00 31.59  ? 437 LEU A C      1 
ATOM   6859  O O      . LEU A 1 437 ? -35.543 -19.146 -1.196  1.00 28.17  ? 437 LEU A O      1 
ATOM   6860  C CB     . LEU A 1 437 ? -32.376 -18.901 -2.018  1.00 26.45  ? 437 LEU A CB     1 
ATOM   6861  C CG     . LEU A 1 437 ? -30.929 -19.330 -2.243  1.00 27.31  ? 437 LEU A CG     1 
ATOM   6862  C CD1    . LEU A 1 437 ? -30.363 -18.616 -3.460  1.00 25.26  ? 437 LEU A CD1    1 
ATOM   6863  C CD2    . LEU A 1 437 ? -30.066 -19.053 -1.017  1.00 28.57  ? 437 LEU A CD2    1 
ATOM   6864  H H      . LEU A 1 437 ? -33.968 -20.992 -2.314  1.00 37.55  ? 437 LEU A H      1 
ATOM   6865  H HA     . LEU A 1 437 ? -32.689 -19.810 -0.208  1.00 38.40  ? 437 LEU A HA     1 
ATOM   6866  H HB2    . LEU A 1 437 ? -32.820 -18.942 -2.879  1.00 31.74  ? 437 LEU A HB2    1 
ATOM   6867  H HB3    . LEU A 1 437 ? -32.354 -17.979 -1.717  1.00 31.74  ? 437 LEU A HB3    1 
ATOM   6868  H HG     . LEU A 1 437 ? -30.906 -20.284 -2.417  1.00 32.77  ? 437 LEU A HG     1 
ATOM   6869  H HD11   . LEU A 1 437 ? -29.435 -18.874 -3.574  1.00 30.31  ? 437 LEU A HD11   1 
ATOM   6870  H HD12   . LEU A 1 437 ? -30.876 -18.871 -4.243  1.00 30.31  ? 437 LEU A HD12   1 
ATOM   6871  H HD13   . LEU A 1 437 ? -30.425 -17.658 -3.321  1.00 30.31  ? 437 LEU A HD13   1 
ATOM   6872  H HD21   . LEU A 1 437 ? -29.149 -19.301 -1.214  1.00 34.29  ? 437 LEU A HD21   1 
ATOM   6873  H HD22   . LEU A 1 437 ? -30.115 -18.108 -0.804  1.00 34.29  ? 437 LEU A HD22   1 
ATOM   6874  H HD23   . LEU A 1 437 ? -30.398 -19.578 -0.272  1.00 34.29  ? 437 LEU A HD23   1 
ATOM   6875  N N      . LYS A 1 438 ? -34.285 -17.960 0.259   1.00 33.51  ? 438 LYS A N      1 
ATOM   6876  C CA     . LYS A 1 438 ? -35.310 -16.969 0.566   1.00 34.85  ? 438 LYS A CA     1 
ATOM   6877  C C      . LYS A 1 438 ? -34.663 -15.593 0.687   1.00 31.34  ? 438 LYS A C      1 
ATOM   6878  O O      . LYS A 1 438 ? -33.475 -15.493 0.990   1.00 31.50  ? 438 LYS A O      1 
ATOM   6879  C CB     . LYS A 1 438 ? -36.030 -17.320 1.865   1.00 36.49  ? 438 LYS A CB     1 
ATOM   6880  C CG     . LYS A 1 438 ? -35.103 -17.401 3.070   1.00 44.46  ? 438 LYS A CG     1 
ATOM   6881  C CD     . LYS A 1 438 ? -35.878 -17.645 4.349   1.00 49.08  ? 438 LYS A CD     1 
ATOM   6882  C CE     . LYS A 1 438 ? -34.949 -17.763 5.535   1.00 56.75  ? 438 LYS A CE     1 
ATOM   6883  N NZ     . LYS A 1 438 ? -35.719 -18.004 6.774   1.00 68.76  ? 438 LYS A NZ     1 
ATOM   6884  H H      . LYS A 1 438 ? -33.568 -17.869 0.725   1.00 40.21  ? 438 LYS A H      1 
ATOM   6885  H HA     . LYS A 1 438 ? -35.963 -16.938 -0.150  1.00 41.82  ? 438 LYS A HA     1 
ATOM   6886  H HB2    . LYS A 1 438 ? -36.697 -16.640 2.048   1.00 43.78  ? 438 LYS A HB2    1 
ATOM   6887  H HB3    . LYS A 1 438 ? -36.460 -18.183 1.762   1.00 43.78  ? 438 LYS A HB3    1 
ATOM   6888  H HG2    . LYS A 1 438 ? -34.482 -18.135 2.947   1.00 53.35  ? 438 LYS A HG2    1 
ATOM   6889  H HG3    . LYS A 1 438 ? -34.621 -16.565 3.166   1.00 53.35  ? 438 LYS A HG3    1 
ATOM   6890  H HD2    . LYS A 1 438 ? -36.481 -16.901 4.506   1.00 58.89  ? 438 LYS A HD2    1 
ATOM   6891  H HD3    . LYS A 1 438 ? -36.377 -18.473 4.269   1.00 58.89  ? 438 LYS A HD3    1 
ATOM   6892  H HE2    . LYS A 1 438 ? -34.344 -18.509 5.399   1.00 68.11  ? 438 LYS A HE2    1 
ATOM   6893  H HE3    . LYS A 1 438 ? -34.451 -16.937 5.639   1.00 68.11  ? 438 LYS A HE3    1 
ATOM   6894  H HZ1    . LYS A 1 438 ? -36.387 -18.569 6.610   1.00 82.51  ? 438 LYS A HZ1    1 
ATOM   6895  H HZ2    . LYS A 1 438 ? -35.191 -18.356 7.397   1.00 82.51  ? 438 LYS A HZ2    1 
ATOM   6896  H HZ3    . LYS A 1 438 ? -36.057 -17.238 7.077   1.00 82.51  ? 438 LYS A HZ3    1 
ATOM   6897  N N      . PHE A 1 439 ? -35.443 -14.544 0.462   1.00 29.00  ? 439 PHE A N      1 
ATOM   6898  C CA     . PHE A 1 439 ? -34.956 -13.179 0.650   1.00 33.83  ? 439 PHE A CA     1 
ATOM   6899  C C      . PHE A 1 439 ? -34.592 -12.908 2.101   1.00 41.02  ? 439 PHE A C      1 
ATOM   6900  O O      . PHE A 1 439 ? -35.274 -13.372 3.017   1.00 35.98  ? 439 PHE A O      1 
ATOM   6901  C CB     . PHE A 1 439 ? -36.004 -12.152 0.215   1.00 35.86  ? 439 PHE A CB     1 
ATOM   6902  C CG     . PHE A 1 439 ? -36.172 -12.029 -1.277  1.00 40.14  ? 439 PHE A CG     1 
ATOM   6903  C CD1    . PHE A 1 439 ? -35.238 -11.346 -2.043  1.00 42.30  ? 439 PHE A CD1    1 
ATOM   6904  C CD2    . PHE A 1 439 ? -37.281 -12.569 -1.908  1.00 39.66  ? 439 PHE A CD2    1 
ATOM   6905  C CE1    . PHE A 1 439 ? -35.401 -11.221 -3.416  1.00 39.59  ? 439 PHE A CE1    1 
ATOM   6906  C CE2    . PHE A 1 439 ? -37.451 -12.447 -3.274  1.00 39.01  ? 439 PHE A CE2    1 
ATOM   6907  C CZ     . PHE A 1 439 ? -36.509 -11.774 -4.031  1.00 41.65  ? 439 PHE A CZ     1 
ATOM   6908  H H      . PHE A 1 439 ? -36.260 -14.593 0.199   1.00 34.80  ? 439 PHE A H      1 
ATOM   6909  H HA     . PHE A 1 439 ? -34.161 -13.048 0.109   1.00 40.59  ? 439 PHE A HA     1 
ATOM   6910  H HB2    . PHE A 1 439 ? -36.862 -12.407 0.588   1.00 43.03  ? 439 PHE A HB2    1 
ATOM   6911  H HB3    . PHE A 1 439 ? -35.745 -11.281 0.555   1.00 43.03  ? 439 PHE A HB3    1 
ATOM   6912  H HD1    . PHE A 1 439 ? -34.491 -10.974 -1.633  1.00 50.76  ? 439 PHE A HD1    1 
ATOM   6913  H HD2    . PHE A 1 439 ? -37.918 -13.024 -1.406  1.00 47.59  ? 439 PHE A HD2    1 
ATOM   6914  H HE1    . PHE A 1 439 ? -34.766 -10.767 -3.921  1.00 47.51  ? 439 PHE A HE1    1 
ATOM   6915  H HE2    . PHE A 1 439 ? -38.197 -12.821 -3.685  1.00 46.81  ? 439 PHE A HE2    1 
ATOM   6916  H HZ     . PHE A 1 439 ? -36.621 -11.693 -4.951  1.00 49.98  ? 439 PHE A HZ     1 
ATOM   6917  N N      . VAL A 1 440 ? -33.507 -12.165 2.304   1.00 38.85  ? 440 VAL A N      1 
ATOM   6918  C CA     . VAL A 1 440 ? -33.274 -11.479 3.571   1.00 37.08  ? 440 VAL A CA     1 
ATOM   6919  C C      . VAL A 1 440 ? -33.296 -9.976  3.289   1.00 38.85  ? 440 VAL A C      1 
ATOM   6920  O O      . VAL A 1 440 ? -33.523 -9.172  4.188   1.00 35.49  ? 440 VAL A O      1 
ATOM   6921  C CB     . VAL A 1 440 ? -31.942 -11.894 4.248   1.00 36.01  ? 440 VAL A CB     1 
ATOM   6922  C CG1    . VAL A 1 440 ? -32.024 -13.337 4.766   1.00 40.36  ? 440 VAL A CG1    1 
ATOM   6923  C CG2    . VAL A 1 440 ? -30.767 -11.720 3.300   1.00 42.44  ? 440 VAL A CG2    1 
ATOM   6924  H H      . VAL A 1 440 ? -32.887 -12.045 1.721   1.00 46.62  ? 440 VAL A H      1 
ATOM   6925  H HA     . VAL A 1 440 ? -33.995 -11.676 4.188   1.00 44.49  ? 440 VAL A HA     1 
ATOM   6926  H HB     . VAL A 1 440 ? -31.790 -11.316 5.012   1.00 43.21  ? 440 VAL A HB     1 
ATOM   6927  H HG11   . VAL A 1 440 ? -31.180 -13.571 5.184   1.00 48.43  ? 440 VAL A HG11   1 
ATOM   6928  H HG12   . VAL A 1 440 ? -32.743 -13.399 5.414   1.00 48.43  ? 440 VAL A HG12   1 
ATOM   6929  H HG13   . VAL A 1 440 ? -32.199 -13.931 4.019   1.00 48.43  ? 440 VAL A HG13   1 
ATOM   6930  H HG21   . VAL A 1 440 ? -29.951 -11.968 3.763   1.00 50.93  ? 440 VAL A HG21   1 
ATOM   6931  H HG22   . VAL A 1 440 ? -30.896 -12.293 2.529   1.00 50.93  ? 440 VAL A HG22   1 
ATOM   6932  H HG23   . VAL A 1 440 ? -30.718 -10.793 3.020   1.00 50.93  ? 440 VAL A HG23   1 
ATOM   6933  N N      . TYR A 1 441 ? -33.074 -9.605  2.028   1.00 38.72  ? 441 TYR A N      1 
ATOM   6934  C CA     . TYR A 1 441 ? -33.198 -8.212  1.585   1.00 36.73  ? 441 TYR A CA     1 
ATOM   6935  C C      . TYR A 1 441 ? -33.662 -8.139  0.136   1.00 40.52  ? 441 TYR A C      1 
ATOM   6936  O O      . TYR A 1 441 ? -33.036 -8.732  -0.753  1.00 37.95  ? 441 TYR A O      1 
ATOM   6937  C CB     . TYR A 1 441 ? -31.872 -7.459  1.729   1.00 35.74  ? 441 TYR A CB     1 
ATOM   6938  C CG     . TYR A 1 441 ? -31.863 -6.136  0.985   1.00 37.24  ? 441 TYR A CG     1 
ATOM   6939  C CD1    . TYR A 1 441 ? -32.549 -5.032  1.483   1.00 42.68  ? 441 TYR A CD1    1 
ATOM   6940  C CD2    . TYR A 1 441 ? -31.181 -5.992  -0.219  1.00 39.78  ? 441 TYR A CD2    1 
ATOM   6941  C CE1    . TYR A 1 441 ? -32.555 -3.823  0.803   1.00 39.67  ? 441 TYR A CE1    1 
ATOM   6942  C CE2    . TYR A 1 441 ? -31.180 -4.786  -0.907  1.00 37.51  ? 441 TYR A CE2    1 
ATOM   6943  C CZ     . TYR A 1 441 ? -31.870 -3.705  -0.391  1.00 46.12  ? 441 TYR A CZ     1 
ATOM   6944  O OH     . TYR A 1 441 ? -31.875 -2.505  -1.065  1.00 39.57  ? 441 TYR A OH     1 
ATOM   6945  H H      . TYR A 1 441 ? -32.843 -10.143 1.399   1.00 46.46  ? 441 TYR A H      1 
ATOM   6946  H HA     . TYR A 1 441 ? -33.860 -7.761  2.132   1.00 44.07  ? 441 TYR A HA     1 
ATOM   6947  H HB2    . TYR A 1 441 ? -31.713 -7.276  2.668   1.00 42.89  ? 441 TYR A HB2    1 
ATOM   6948  H HB3    . TYR A 1 441 ? -31.157 -8.008  1.372   1.00 42.89  ? 441 TYR A HB3    1 
ATOM   6949  H HD1    . TYR A 1 441 ? -33.014 -5.107  2.285   1.00 51.22  ? 441 TYR A HD1    1 
ATOM   6950  H HD2    . TYR A 1 441 ? -30.718 -6.718  -0.571  1.00 47.73  ? 441 TYR A HD2    1 
ATOM   6951  H HE1    . TYR A 1 441 ? -33.018 -3.095  1.150   1.00 47.60  ? 441 TYR A HE1    1 
ATOM   6952  H HE2    . TYR A 1 441 ? -30.719 -4.706  -1.711  1.00 45.01  ? 441 TYR A HE2    1 
ATOM   6953  H HH     . TYR A 1 441 ? -31.429 -2.572  -1.774  1.00 47.49  ? 441 TYR A HH     1 
ATOM   6954  N N      . GLU A 1 442 ? -34.743 -7.400  -0.103  1.00 35.13  ? 442 GLU A N      1 
ATOM   6955  C CA     . GLU A 1 442 ? -35.289 -7.252  -1.449  1.00 37.03  ? 442 GLU A CA     1 
ATOM   6956  C C      . GLU A 1 442 ? -35.521 -5.787  -1.817  1.00 41.23  ? 442 GLU A C      1 
ATOM   6957  O O      . GLU A 1 442 ? -36.359 -5.129  -1.206  1.00 47.23  ? 442 GLU A O      1 
ATOM   6958  C CB     . GLU A 1 442 ? -36.607 -8.017  -1.588  1.00 41.71  ? 442 GLU A CB     1 
ATOM   6959  C CG     . GLU A 1 442 ? -37.198 -7.931  -2.994  1.00 42.40  ? 442 GLU A CG     1 
ATOM   6960  C CD     . GLU A 1 442 ? -38.511 -8.673  -3.138  1.00 46.28  ? 442 GLU A CD     1 
ATOM   6961  O OE1    . GLU A 1 442 ? -39.099 -8.620  -4.239  1.00 40.25  ? 442 GLU A OE1    1 
ATOM   6962  O OE2    . GLU A 1 442 ? -38.953 -9.303  -2.153  1.00 44.02  ? 442 GLU A OE2    1 
ATOM   6963  H H      . GLU A 1 442 ? -35.181 -6.972  0.501   1.00 42.16  ? 442 GLU A H      1 
ATOM   6964  H HA     . GLU A 1 442 ? -34.680 -7.649  -2.084  1.00 44.44  ? 442 GLU A HA     1 
ATOM   6965  H HB2    . GLU A 1 442 ? -36.453 -8.952  -1.383  1.00 50.06  ? 442 GLU A HB2    1 
ATOM   6966  H HB3    . GLU A 1 442 ? -37.254 -7.644  -0.969  1.00 50.06  ? 442 GLU A HB3    1 
ATOM   6967  H HG2    . GLU A 1 442 ? -37.366 -7.003  -3.214  1.00 50.89  ? 442 GLU A HG2    1 
ATOM   6968  H HG3    . GLU A 1 442 ? -36.568 -8.313  -3.625  1.00 50.89  ? 442 GLU A HG3    1 
ATOM   6969  N N      . PRO A 1 443 ? -34.791 -5.276  -2.830  1.00 41.93  ? 443 PRO A N      1 
ATOM   6970  C CA     . PRO A 1 443 ? -35.048 -3.927  -3.347  1.00 42.34  ? 443 PRO A CA     1 
ATOM   6971  C C      . PRO A 1 443 ? -36.397 -3.842  -4.045  1.00 46.38  ? 443 PRO A C      1 
ATOM   6972  O O      . PRO A 1 443 ? -36.909 -4.875  -4.472  1.00 45.12  ? 443 PRO A O      1 
ATOM   6973  C CB     . PRO A 1 443 ? -33.913 -3.700  -4.357  1.00 45.52  ? 443 PRO A CB     1 
ATOM   6974  C CG     . PRO A 1 443 ? -32.937 -4.791  -4.128  1.00 45.53  ? 443 PRO A CG     1 
ATOM   6975  C CD     . PRO A 1 443 ? -33.690 -5.932  -3.555  1.00 45.91  ? 443 PRO A CD     1 
ATOM   6976  H HA     . PRO A 1 443 ? -34.998 -3.267  -2.638  1.00 50.81  ? 443 PRO A HA     1 
ATOM   6977  H HB2    . PRO A 1 443 ? -34.268 -3.745  -5.259  1.00 54.62  ? 443 PRO A HB2    1 
ATOM   6978  H HB3    . PRO A 1 443 ? -33.502 -2.836  -4.195  1.00 54.62  ? 443 PRO A HB3    1 
ATOM   6979  H HG2    . PRO A 1 443 ? -32.536 -5.045  -4.974  1.00 54.64  ? 443 PRO A HG2    1 
ATOM   6980  H HG3    . PRO A 1 443 ? -32.256 -4.489  -3.507  1.00 54.64  ? 443 PRO A HG3    1 
ATOM   6981  H HD2    . PRO A 1 443 ? -34.037 -6.500  -4.261  1.00 55.09  ? 443 PRO A HD2    1 
ATOM   6982  H HD3    . PRO A 1 443 ? -33.123 -6.426  -2.943  1.00 55.09  ? 443 PRO A HD3    1 
ATOM   6983  N N      . LYS A 1 444 ? -36.955 -2.641  -4.178  1.00 49.25  ? 444 LYS A N      1 
ATOM   6984  C CA     . LYS A 1 444 ? -38.251 -2.484  -4.834  1.00 53.47  ? 444 LYS A CA     1 
ATOM   6985  C C      . LYS A 1 444 ? -38.115 -2.443  -6.361  1.00 52.39  ? 444 LYS A C      1 
ATOM   6986  O O      . LYS A 1 444 ? -39.108 -2.562  -7.078  1.00 52.04  ? 444 LYS A O      1 
ATOM   6987  C CB     . LYS A 1 444 ? -38.964 -1.221  -4.333  1.00 57.54  ? 444 LYS A CB     1 
ATOM   6988  C CG     . LYS A 1 444 ? -40.468 -1.243  -4.604  1.00 79.69  ? 444 LYS A CG     1 
ATOM   6989  C CD     . LYS A 1 444 ? -41.222 -0.106  -3.922  1.00 79.24  ? 444 LYS A CD     1 
ATOM   6990  C CE     . LYS A 1 444 ? -42.731 -0.269  -4.113  1.00 83.15  ? 444 LYS A CE     1 
ATOM   6991  N NZ     . LYS A 1 444 ? -43.523 0.845   -3.516  1.00 82.74  ? 444 LYS A NZ     1 
ATOM   6992  H H      . LYS A 1 444 ? -36.607 -1.906  -3.899  1.00 59.10  ? 444 LYS A H      1 
ATOM   6993  H HA     . LYS A 1 444 ? -38.811 -3.243  -4.608  1.00 64.16  ? 444 LYS A HA     1 
ATOM   6994  H HB2    . LYS A 1 444 ? -38.833 -1.143  -3.375  1.00 69.05  ? 444 LYS A HB2    1 
ATOM   6995  H HB3    . LYS A 1 444 ? -38.590 -0.447  -4.783  1.00 69.05  ? 444 LYS A HB3    1 
ATOM   6996  H HG2    . LYS A 1 444 ? -40.617 -1.166  -5.559  1.00 95.63  ? 444 LYS A HG2    1 
ATOM   6997  H HG3    . LYS A 1 444 ? -40.834 -2.080  -4.279  1.00 95.63  ? 444 LYS A HG3    1 
ATOM   6998  H HD2    . LYS A 1 444 ? -41.030 -0.116  -2.971  1.00 95.08  ? 444 LYS A HD2    1 
ATOM   6999  H HD3    . LYS A 1 444 ? -40.953 0.740   -4.313  1.00 95.08  ? 444 LYS A HD3    1 
ATOM   7000  H HE2    . LYS A 1 444 ? -42.926 -0.299  -5.063  1.00 99.78  ? 444 LYS A HE2    1 
ATOM   7001  H HE3    . LYS A 1 444 ? -43.014 -1.096  -3.691  1.00 99.78  ? 444 LYS A HE3    1 
ATOM   7002  H HZ1    . LYS A 1 444 ? -44.392 0.707   -3.652  1.00 99.28  ? 444 LYS A HZ1    1 
ATOM   7003  H HZ2    . LYS A 1 444 ? -43.371 0.891   -2.640  1.00 99.28  ? 444 LYS A HZ2    1 
ATOM   7004  H HZ3    . LYS A 1 444 ? -43.291 1.618   -3.891  1.00 99.28  ? 444 LYS A HZ3    1 
ATOM   7005  N N      . GLN A 1 445 ? -36.890 -2.279  -6.855  1.00 54.39  ? 445 GLN A N      1 
ATOM   7006  C CA     . GLN A 1 445 ? -36.632 -2.327  -8.296  1.00 53.81  ? 445 GLN A CA     1 
ATOM   7007  C C      . GLN A 1 445 ? -35.231 -2.885  -8.592  1.00 44.04  ? 445 GLN A C      1 
ATOM   7008  O O      . GLN A 1 445 ? -34.345 -2.841  -7.736  1.00 43.01  ? 445 GLN A O      1 
ATOM   7009  C CB     . GLN A 1 445 ? -36.800 -0.935  -8.922  1.00 58.16  ? 445 GLN A CB     1 
ATOM   7010  C CG     . GLN A 1 445 ? -35.721 0.095   -8.554  1.00 66.40  ? 445 GLN A CG     1 
ATOM   7011  C CD     . GLN A 1 445 ? -35.968 0.782   -7.218  1.00 64.92  ? 445 GLN A CD     1 
ATOM   7012  O OE1    . GLN A 1 445 ? -35.630 0.253   -6.157  1.00 61.47  ? 445 GLN A OE1    1 
ATOM   7013  N NE2    . GLN A 1 445 ? -36.547 1.979   -7.269  1.00 61.05  ? 445 GLN A NE2    1 
ATOM   7014  H H      . GLN A 1 445 ? -36.188 -2.137  -6.379  1.00 65.27  ? 445 GLN A H      1 
ATOM   7015  H HA     . GLN A 1 445 ? -37.276 -2.920  -8.714  1.00 64.57  ? 445 GLN A HA     1 
ATOM   7016  H HB2    . GLN A 1 445 ? -36.793 -1.031  -9.887  1.00 69.79  ? 445 GLN A HB2    1 
ATOM   7017  H HB3    . GLN A 1 445 ? -37.655 -0.573  -8.640  1.00 69.79  ? 445 GLN A HB3    1 
ATOM   7018  H HG2    . GLN A 1 445 ? -34.855 -0.338  -8.509  1.00 79.68  ? 445 GLN A HG2    1 
ATOM   7019  H HG3    . GLN A 1 445 ? -35.705 0.783   -9.238  1.00 79.68  ? 445 GLN A HG3    1 
ATOM   7020  H HE21   . GLN A 1 445 ? -36.760 2.322   -8.029  1.00 73.26  ? 445 GLN A HE21   1 
ATOM   7021  H HE22   . GLN A 1 445 ? -36.708 2.410   -6.542  1.00 73.26  ? 445 GLN A HE22   1 
ATOM   7022  N N      . LEU A 1 446 ? -35.043 -3.404  -9.805  1.00 44.81  ? 446 LEU A N      1 
ATOM   7023  C CA     . LEU A 1 446 ? -33.804 -4.094  -10.179 1.00 41.55  ? 446 LEU A CA     1 
ATOM   7024  C C      . LEU A 1 446 ? -33.385 -5.101  -9.124  1.00 39.62  ? 446 LEU A C      1 
ATOM   7025  O O      . LEU A 1 446 ? -32.223 -5.117  -8.707  1.00 33.73  ? 446 LEU A O      1 
ATOM   7026  C CB     . LEU A 1 446 ? -32.651 -3.108  -10.381 1.00 43.74  ? 446 LEU A CB     1 
ATOM   7027  C CG     . LEU A 1 446 ? -32.585 -2.206  -11.603 1.00 45.50  ? 446 LEU A CG     1 
ATOM   7028  C CD1    . LEU A 1 446 ? -31.213 -1.544  -11.594 1.00 47.28  ? 446 LEU A CD1    1 
ATOM   7029  C CD2    . LEU A 1 446 ? -32.810 -2.974  -12.896 1.00 45.57  ? 446 LEU A CD2    1 
ATOM   7030  H H      . LEU A 1 446 ? -35.624 -3.370  -10.438 1.00 53.78  ? 446 LEU A H      1 
ATOM   7031  H HA     . LEU A 1 446 ? -33.946 -4.573  -11.010 1.00 49.86  ? 446 LEU A HA     1 
ATOM   7032  H HB2    . LEU A 1 446 ? -32.626 -2.524  -9.607  1.00 52.49  ? 446 LEU A HB2    1 
ATOM   7033  H HB3    . LEU A 1 446 ? -31.828 -3.618  -10.413 1.00 52.49  ? 446 LEU A HB3    1 
ATOM   7034  H HG     . LEU A 1 446 ? -33.262 -1.514  -11.533 1.00 54.60  ? 446 LEU A HG     1 
ATOM   7035  H HD11   . LEU A 1 446 ? -31.148 -0.942  -12.352 1.00 56.74  ? 446 LEU A HD11   1 
ATOM   7036  H HD12   . LEU A 1 446 ? -31.108 -1.048  -10.767 1.00 56.74  ? 446 LEU A HD12   1 
ATOM   7037  H HD13   . LEU A 1 446 ? -30.530 -2.230  -11.658 1.00 56.74  ? 446 LEU A HD13   1 
ATOM   7038  H HD21   . LEU A 1 446 ? -32.667 -2.376  -13.647 1.00 54.69  ? 446 LEU A HD21   1 
ATOM   7039  H HD22   . LEU A 1 446 ? -32.183 -3.713  -12.937 1.00 54.69  ? 446 LEU A HD22   1 
ATOM   7040  H HD23   . LEU A 1 446 ? -33.720 -3.310  -12.910 1.00 54.69  ? 446 LEU A HD23   1 
ATOM   7041  N N      . ARG A 1 447 ? -34.314 -5.933  -8.669  1.00 38.11  ? 447 ARG A N      1 
ATOM   7042  C CA     . ARG A 1 447 ? -34.030 -6.721  -7.478  1.00 42.70  ? 447 ARG A CA     1 
ATOM   7043  C C      . ARG A 1 447 ? -32.892 -7.714  -7.721  1.00 33.37  ? 447 ARG A C      1 
ATOM   7044  O O      . ARG A 1 447 ? -32.144 -8.034  -6.793  1.00 34.77  ? 447 ARG A O      1 
ATOM   7045  C CB     . ARG A 1 447 ? -35.289 -7.441  -6.979  1.00 43.91  ? 447 ARG A CB     1 
ATOM   7046  C CG     . ARG A 1 447 ? -35.878 -8.497  -7.889  1.00 44.06  ? 447 ARG A CG     1 
ATOM   7047  C CD     . ARG A 1 447 ? -37.015 -9.198  -7.153  1.00 46.49  ? 447 ARG A CD     1 
ATOM   7048  N NE     . ARG A 1 447 ? -37.605 -10.302 -7.905  1.00 42.43  ? 447 ARG A NE     1 
ATOM   7049  C CZ     . ARG A 1 447 ? -38.578 -11.080 -7.440  1.00 47.79  ? 447 ARG A CZ     1 
ATOM   7050  N NH1    . ARG A 1 447 ? -39.067 -10.882 -6.219  1.00 45.92  ? 447 ARG A NH1    1 
ATOM   7051  N NH2    . ARG A 1 447 ? -39.061 -12.062 -8.192  1.00 48.02  ? 447 ARG A NH2    1 
ATOM   7052  H H      . ARG A 1 447 ? -35.090 -6.057  -9.017  1.00 45.74  ? 447 ARG A H      1 
ATOM   7053  H HA     . ARG A 1 447 ? -33.743 -6.118  -6.774  1.00 51.24  ? 447 ARG A HA     1 
ATOM   7054  H HB2    . ARG A 1 447 ? -35.075 -7.874  -6.138  1.00 52.70  ? 447 ARG A HB2    1 
ATOM   7055  H HB3    . ARG A 1 447 ? -35.978 -6.775  -6.829  1.00 52.70  ? 447 ARG A HB3    1 
ATOM   7056  H HG2    . ARG A 1 447 ? -36.233 -8.083  -8.690  1.00 52.88  ? 447 ARG A HG2    1 
ATOM   7057  H HG3    . ARG A 1 447 ? -35.201 -9.154  -8.113  1.00 52.88  ? 447 ARG A HG3    1 
ATOM   7058  H HD2    . ARG A 1 447 ? -36.675 -9.556  -6.318  1.00 55.78  ? 447 ARG A HD2    1 
ATOM   7059  H HD3    . ARG A 1 447 ? -37.716 -8.553  -6.973  1.00 55.78  ? 447 ARG A HD3    1 
ATOM   7060  H HE     . ARG A 1 447 ? -37.364 -10.405 -8.724  1.00 50.92  ? 447 ARG A HE     1 
ATOM   7061  H HH11   . ARG A 1 447 ? -38.759 -10.248 -5.727  1.00 55.10  ? 447 ARG A HH11   1 
ATOM   7062  H HH12   . ARG A 1 447 ? -39.695 -11.388 -5.921  1.00 55.10  ? 447 ARG A HH12   1 
ATOM   7063  H HH21   . ARG A 1 447 ? -38.745 -12.193 -8.981  1.00 57.62  ? 447 ARG A HH21   1 
ATOM   7064  H HH22   . ARG A 1 447 ? -39.688 -12.567 -7.891  1.00 57.62  ? 447 ARG A HH22   1 
ATOM   7065  N N      . PHE A 1 448 ? -32.729 -8.168  -8.961  1.00 35.11  ? 448 PHE A N      1 
ATOM   7066  C CA     . PHE A 1 448 ? -31.668 -9.127  -9.272  1.00 36.78  ? 448 PHE A CA     1 
ATOM   7067  C C      . PHE A 1 448 ? -30.288 -8.522  -9.015  1.00 33.70  ? 448 PHE A C      1 
ATOM   7068  O O      . PHE A 1 448 ? -29.317 -9.241  -8.769  1.00 29.56  ? 448 PHE A O      1 
ATOM   7069  C CB     . PHE A 1 448 ? -31.766 -9.601  -10.727 1.00 31.22  ? 448 PHE A CB     1 
ATOM   7070  C CG     . PHE A 1 448 ? -31.543 -8.511  -11.735 1.00 33.60  ? 448 PHE A CG     1 
ATOM   7071  C CD1    . PHE A 1 448 ? -30.261 -8.155  -12.122 1.00 34.74  ? 448 PHE A CD1    1 
ATOM   7072  C CD2    . PHE A 1 448 ? -32.618 -7.840  -12.295 1.00 38.55  ? 448 PHE A CD2    1 
ATOM   7073  C CE1    . PHE A 1 448 ? -30.053 -7.148  -13.047 1.00 38.92  ? 448 PHE A CE1    1 
ATOM   7074  C CE2    . PHE A 1 448 ? -32.419 -6.833  -13.221 1.00 41.52  ? 448 PHE A CE2    1 
ATOM   7075  C CZ     . PHE A 1 448 ? -31.133 -6.484  -13.597 1.00 41.46  ? 448 PHE A CZ     1 
ATOM   7076  H H      . PHE A 1 448 ? -33.213 -7.941  -9.635  1.00 42.13  ? 448 PHE A H      1 
ATOM   7077  H HA     . PHE A 1 448 ? -31.766 -9.902  -8.698  1.00 44.13  ? 448 PHE A HA     1 
ATOM   7078  H HB2    . PHE A 1 448 ? -31.097 -10.287 -10.878 1.00 37.46  ? 448 PHE A HB2    1 
ATOM   7079  H HB3    . PHE A 1 448 ? -32.651 -9.967  -10.875 1.00 37.46  ? 448 PHE A HB3    1 
ATOM   7080  H HD1    . PHE A 1 448 ? -29.531 -8.597  -11.753 1.00 41.69  ? 448 PHE A HD1    1 
ATOM   7081  H HD2    . PHE A 1 448 ? -33.484 -8.069  -12.044 1.00 46.26  ? 448 PHE A HD2    1 
ATOM   7082  H HE1    . PHE A 1 448 ? -29.188 -6.918  -13.298 1.00 46.70  ? 448 PHE A HE1    1 
ATOM   7083  H HE2    . PHE A 1 448 ? -33.148 -6.389  -13.590 1.00 49.83  ? 448 PHE A HE2    1 
ATOM   7084  H HZ     . PHE A 1 448 ? -30.997 -5.809  -14.222 1.00 49.75  ? 448 PHE A HZ     1 
ATOM   7085  N N      . PHE A 1 449 ? -30.211 -7.196  -9.069  1.00 33.54  ? 449 PHE A N      1 
ATOM   7086  C CA     . PHE A 1 449 ? -28.934 -6.499  -8.999  1.00 34.69  ? 449 PHE A CA     1 
ATOM   7087  C C      . PHE A 1 449 ? -28.365 -6.453  -7.583  1.00 36.50  ? 449 PHE A C      1 
ATOM   7088  O O      . PHE A 1 449 ? -27.155 -6.552  -7.412  1.00 29.63  ? 449 PHE A O      1 
ATOM   7089  C CB     . PHE A 1 449 ? -29.081 -5.077  -9.553  1.00 38.57  ? 449 PHE A CB     1 
ATOM   7090  C CG     . PHE A 1 449 ? -27.768 -4.393  -9.837  1.00 40.82  ? 449 PHE A CG     1 
ATOM   7091  C CD1    . PHE A 1 449 ? -26.875 -4.929  -10.756 1.00 42.61  ? 449 PHE A CD1    1 
ATOM   7092  C CD2    . PHE A 1 449 ? -27.434 -3.209  -9.197  1.00 38.37  ? 449 PHE A CD2    1 
ATOM   7093  C CE1    . PHE A 1 449 ? -25.663 -4.303  -11.026 1.00 39.10  ? 449 PHE A CE1    1 
ATOM   7094  C CE2    . PHE A 1 449 ? -26.224 -2.574  -9.463  1.00 43.24  ? 449 PHE A CE2    1 
ATOM   7095  C CZ     . PHE A 1 449 ? -25.338 -3.125  -10.380 1.00 38.01  ? 449 PHE A CZ     1 
ATOM   7096  H H      . PHE A 1 449 ? -30.889 -6.673  -9.147  1.00 40.25  ? 449 PHE A H      1 
ATOM   7097  H HA     . PHE A 1 449 ? -28.295 -6.970  -9.557  1.00 41.63  ? 449 PHE A HA     1 
ATOM   7098  H HB2    . PHE A 1 449 ? -29.581 -5.116  -10.383 1.00 46.28  ? 449 PHE A HB2    1 
ATOM   7099  H HB3    . PHE A 1 449 ? -29.561 -4.538  -8.906  1.00 46.28  ? 449 PHE A HB3    1 
ATOM   7100  H HD1    . PHE A 1 449 ? -27.088 -5.722  -11.193 1.00 51.13  ? 449 PHE A HD1    1 
ATOM   7101  H HD2    . PHE A 1 449 ? -28.023 -2.837  -8.581  1.00 46.04  ? 449 PHE A HD2    1 
ATOM   7102  H HE1    . PHE A 1 449 ? -25.073 -4.675  -11.642 1.00 46.92  ? 449 PHE A HE1    1 
ATOM   7103  H HE2    . PHE A 1 449 ? -26.008 -1.782  -9.026  1.00 51.89  ? 449 PHE A HE2    1 
ATOM   7104  H HZ     . PHE A 1 449 ? -24.529 -2.703  -10.559 1.00 45.61  ? 449 PHE A HZ     1 
ATOM   7105  N N      . THR A 1 450 ? -29.227 -6.325  -6.572  1.00 31.58  ? 450 THR A N      1 
ATOM   7106  C CA     . THR A 1 450 ? -28.752 -6.155  -5.194  1.00 32.53  ? 450 THR A CA     1 
ATOM   7107  C C      . THR A 1 450 ? -29.497 -6.979  -4.133  1.00 34.02  ? 450 THR A C      1 
ATOM   7108  O O      . THR A 1 450 ? -29.199 -6.857  -2.943  1.00 36.12  ? 450 THR A O      1 
ATOM   7109  C CB     . THR A 1 450 ? -28.829 -4.671  -4.770  1.00 39.51  ? 450 THR A CB     1 
ATOM   7110  O OG1    . THR A 1 450 ? -30.150 -4.172  -5.004  1.00 36.57  ? 450 THR A OG1    1 
ATOM   7111  C CG2    . THR A 1 450 ? -27.825 -3.838  -5.556  1.00 37.84  ? 450 THR A CG2    1 
ATOM   7112  H H      . THR A 1 450 ? -30.083 -6.333  -6.654  1.00 37.89  ? 450 THR A H      1 
ATOM   7113  H HA     . THR A 1 450 ? -27.821 -6.418  -5.144  1.00 39.04  ? 450 THR A HA     1 
ATOM   7114  H HB     . THR A 1 450 ? -28.617 -4.590  -3.827  1.00 47.42  ? 450 THR A HB     1 
ATOM   7115  H HG1    . THR A 1 450 ? -30.197 -3.365  -4.775  1.00 43.88  ? 450 THR A HG1    1 
ATOM   7116  H HG21   . THR A 1 450 ? -27.860 -2.914  -5.263  1.00 45.41  ? 450 THR A HG21   1 
ATOM   7117  H HG22   . THR A 1 450 ? -26.928 -4.180  -5.415  1.00 45.41  ? 450 THR A HG22   1 
ATOM   7118  H HG23   . THR A 1 450 ? -28.032 -3.877  -6.503  1.00 45.41  ? 450 THR A HG23   1 
ATOM   7119  N N      . ALA A 1 451 ? -30.444 -7.820  -4.539  1.00 32.76  ? 451 ALA A N      1 
ATOM   7120  C CA     . ALA A 1 451 ? -31.138 -8.677  -3.575  1.00 31.80  ? 451 ALA A CA     1 
ATOM   7121  C C      . ALA A 1 451 ? -30.161 -9.578  -2.826  1.00 34.99  ? 451 ALA A C      1 
ATOM   7122  O O      . ALA A 1 451 ? -29.118 -9.970  -3.359  1.00 28.65  ? 451 ALA A O      1 
ATOM   7123  C CB     . ALA A 1 451 ? -32.197 -9.520  -4.267  1.00 35.20  ? 451 ALA A CB     1 
ATOM   7124  H H      . ALA A 1 451 ? -30.702 -7.915  -5.354  1.00 39.31  ? 451 ALA A H      1 
ATOM   7125  H HA     . ALA A 1 451 ? -31.584 -8.116  -2.922  1.00 38.16  ? 451 ALA A HA     1 
ATOM   7126  H HB1    . ALA A 1 451 ? -32.561 -10.152 -3.627  1.00 42.24  ? 451 ALA A HB1    1 
ATOM   7127  H HB2    . ALA A 1 451 ? -32.902 -8.939  -4.592  1.00 42.24  ? 451 ALA A HB2    1 
ATOM   7128  H HB3    . ALA A 1 451 ? -31.788 -9.998  -5.005  1.00 42.24  ? 451 ALA A HB3    1 
ATOM   7129  N N      . ARG A 1 452 ? -30.499 -9.889  -1.577  1.00 29.35  ? 452 ARG A N      1 
ATOM   7130  C CA     . ARG A 1 452 ? -29.708 -10.804 -0.764  1.00 31.54  ? 452 ARG A CA     1 
ATOM   7131  C C      . ARG A 1 452 ? -30.595 -11.921 -0.217  1.00 32.20  ? 452 ARG A C      1 
ATOM   7132  O O      . ARG A 1 452 ? -31.768 -11.696 0.090   1.00 33.20  ? 452 ARG A O      1 
ATOM   7133  C CB     . ARG A 1 452 ? -29.027 -10.060 0.384   1.00 36.58  ? 452 ARG A CB     1 
ATOM   7134  C CG     . ARG A 1 452 ? -28.125 -8.924  -0.074  1.00 41.58  ? 452 ARG A CG     1 
ATOM   7135  C CD     . ARG A 1 452 ? -27.581 -8.156  1.113   1.00 42.98  ? 452 ARG A CD     1 
ATOM   7136  N NE     . ARG A 1 452 ? -26.795 -9.016  1.987   1.00 50.62  ? 452 ARG A NE     1 
ATOM   7137  C CZ     . ARG A 1 452 ? -26.332 -8.646  3.176   1.00 91.46  ? 452 ARG A CZ     1 
ATOM   7138  N NH1    . ARG A 1 452 ? -26.580 -7.424  3.637   1.00 98.80  ? 452 ARG A NH1    1 
ATOM   7139  N NH2    . ARG A 1 452 ? -25.624 -9.497  3.907   1.00 92.41  ? 452 ARG A NH2    1 
ATOM   7140  H H      . ARG A 1 452 ? -31.192 -9.578  -1.174  1.00 35.22  ? 452 ARG A H      1 
ATOM   7141  H HA     . ARG A 1 452 ? -29.017 -11.214 -1.306  1.00 37.85  ? 452 ARG A HA     1 
ATOM   7142  H HB2    . ARG A 1 452 ? -29.709 -9.685  0.962   1.00 43.90  ? 452 ARG A HB2    1 
ATOM   7143  H HB3    . ARG A 1 452 ? -28.483 -10.689 0.883   1.00 43.90  ? 452 ARG A HB3    1 
ATOM   7144  H HG2    . ARG A 1 452 ? -27.376 -9.288  -0.572  1.00 49.89  ? 452 ARG A HG2    1 
ATOM   7145  H HG3    . ARG A 1 452 ? -28.633 -8.311  -0.627  1.00 49.89  ? 452 ARG A HG3    1 
ATOM   7146  H HD2    . ARG A 1 452 ? -27.010 -7.439  0.797   1.00 51.57  ? 452 ARG A HD2    1 
ATOM   7147  H HD3    . ARG A 1 452 ? -28.321 -7.795  1.627   1.00 51.57  ? 452 ARG A HD3    1 
ATOM   7148  H HE     . ARG A 1 452 ? -26.579 -9.796  1.696   1.00 60.74  ? 452 ARG A HE     1 
ATOM   7149  H HH11   . ARG A 1 452 ? -27.039 -6.868  3.168   1.00 118.56 ? 452 ARG A HH11   1 
ATOM   7150  H HH12   . ARG A 1 452 ? -26.279 -7.188  4.407   1.00 118.56 ? 452 ARG A HH12   1 
ATOM   7151  H HH21   . ARG A 1 452 ? -25.463 -10.288 3.610   1.00 110.89 ? 452 ARG A HH21   1 
ATOM   7152  H HH22   . ARG A 1 452 ? -25.325 -9.257  4.677   1.00 110.89 ? 452 ARG A HH22   1 
ATOM   7153  N N      . PHE A 1 453 ? -30.013 -13.110 -0.095  1.00 28.94  ? 453 PHE A N      1 
ATOM   7154  C CA     . PHE A 1 453 ? -30.744 -14.322 0.275   1.00 27.45  ? 453 PHE A CA     1 
ATOM   7155  C C      . PHE A 1 453 ? -30.026 -15.095 1.372   1.00 28.64  ? 453 PHE A C      1 
ATOM   7156  O O      . PHE A 1 453 ? -28.854 -14.850 1.657   1.00 30.16  ? 453 PHE A O      1 
ATOM   7157  C CB     . PHE A 1 453 ? -30.918 -15.256 -0.942  1.00 26.29  ? 453 PHE A CB     1 
ATOM   7158  C CG     . PHE A 1 453 ? -31.464 -14.581 -2.176  1.00 28.13  ? 453 PHE A CG     1 
ATOM   7159  C CD1    . PHE A 1 453 ? -30.608 -13.985 -3.093  1.00 27.49  ? 453 PHE A CD1    1 
ATOM   7160  C CD2    . PHE A 1 453 ? -32.822 -14.569 -2.438  1.00 29.01  ? 453 PHE A CD2    1 
ATOM   7161  C CE1    . PHE A 1 453 ? -31.102 -13.367 -4.232  1.00 25.68  ? 453 PHE A CE1    1 
ATOM   7162  C CE2    . PHE A 1 453 ? -33.319 -13.957 -3.578  1.00 27.55  ? 453 PHE A CE2    1 
ATOM   7163  C CZ     . PHE A 1 453 ? -32.455 -13.350 -4.474  1.00 30.63  ? 453 PHE A CZ     1 
ATOM   7164  H H      . PHE A 1 453 ? -29.174 -13.245 -0.225  1.00 34.72  ? 453 PHE A H      1 
ATOM   7165  H HA     . PHE A 1 453 ? -31.619 -14.074 0.603   1.00 32.94  ? 453 PHE A HA     1 
ATOM   7166  H HB2    . PHE A 1 453 ? -30.053 -15.631 -1.171  1.00 31.55  ? 453 PHE A HB2    1 
ATOM   7167  H HB3    . PHE A 1 453 ? -31.530 -15.969 -0.701  1.00 31.55  ? 453 PHE A HB3    1 
ATOM   7168  H HD1    . PHE A 1 453 ? -29.692 -13.986 -2.933  1.00 32.98  ? 453 PHE A HD1    1 
ATOM   7169  H HD2    . PHE A 1 453 ? -33.409 -14.969 -1.838  1.00 34.81  ? 453 PHE A HD2    1 
ATOM   7170  H HE1    . PHE A 1 453 ? -30.517 -12.965 -4.833  1.00 30.81  ? 453 PHE A HE1    1 
ATOM   7171  H HE2    . PHE A 1 453 ? -34.235 -13.948 -3.738  1.00 33.06  ? 453 PHE A HE2    1 
ATOM   7172  H HZ     . PHE A 1 453 ? -32.788 -12.941 -5.240  1.00 36.76  ? 453 PHE A HZ     1 
ATOM   7173  N N      . ASP A 1 454 ? -30.735 -16.044 1.981   1.00 31.23  ? 454 ASP A N      1 
ATOM   7174  C CA     . ASP A 1 454 ? -30.092 -17.103 2.750   1.00 34.22  ? 454 ASP A CA     1 
ATOM   7175  C C      . ASP A 1 454 ? -30.925 -18.362 2.554   1.00 29.48  ? 454 ASP A C      1 
ATOM   7176  O O      . ASP A 1 454 ? -32.025 -18.313 2.005   1.00 27.76  ? 454 ASP A O      1 
ATOM   7177  C CB     . ASP A 1 454 ? -29.962 -16.756 4.246   1.00 34.31  ? 454 ASP A CB     1 
ATOM   7178  C CG     . ASP A 1 454 ? -28.736 -17.408 4.905   1.00 35.80  ? 454 ASP A CG     1 
ATOM   7179  O OD1    . ASP A 1 454 ? -28.184 -18.385 4.356   1.00 34.43  ? 454 ASP A OD1    1 
ATOM   7180  O OD2    . ASP A 1 454 ? -28.318 -16.948 5.992   1.00 38.89  ? 454 ASP A OD2    1 
ATOM   7181  H H      . ASP A 1 454 ? -31.593 -16.096 1.963   1.00 37.47  ? 454 ASP A H      1 
ATOM   7182  H HA     . ASP A 1 454 ? -29.206 -17.265 2.391   1.00 41.06  ? 454 ASP A HA     1 
ATOM   7183  H HB2    . ASP A 1 454 ? -29.877 -15.794 4.341   1.00 41.17  ? 454 ASP A HB2    1 
ATOM   7184  H HB3    . ASP A 1 454 ? -30.754 -17.067 4.712   1.00 41.17  ? 454 ASP A HB3    1 
ATOM   7185  N N      . TYR A 1 455 ? -30.391 -19.484 3.004   1.00 29.80  ? 455 TYR A N      1 
ATOM   7186  C CA     . TYR A 1 455 ? -31.024 -20.772 2.770   1.00 32.74  ? 455 TYR A CA     1 
ATOM   7187  C C      . TYR A 1 455 ? -32.227 -21.008 3.667   1.00 44.55  ? 455 TYR A C      1 
ATOM   7188  O O      . TYR A 1 455 ? -32.264 -20.553 4.812   1.00 40.49  ? 455 TYR A O      1 
ATOM   7189  C CB     . TYR A 1 455 ? -30.007 -21.883 2.974   1.00 35.36  ? 455 TYR A CB     1 
ATOM   7190  C CG     . TYR A 1 455 ? -28.936 -21.876 1.927   1.00 39.82  ? 455 TYR A CG     1 
ATOM   7191  C CD1    . TYR A 1 455 ? -29.248 -22.136 0.603   1.00 35.49  ? 455 TYR A CD1    1 
ATOM   7192  C CD2    . TYR A 1 455 ? -27.615 -21.606 2.254   1.00 33.09  ? 455 TYR A CD2    1 
ATOM   7193  C CE1    . TYR A 1 455 ? -28.279 -22.127 -0.369  1.00 32.49  ? 455 TYR A CE1    1 
ATOM   7194  C CE2    . TYR A 1 455 ? -26.636 -21.593 1.284   1.00 30.22  ? 455 TYR A CE2    1 
ATOM   7195  C CZ     . TYR A 1 455 ? -26.979 -21.858 -0.023  1.00 29.48  ? 455 TYR A CZ     1 
ATOM   7196  O OH     . TYR A 1 455 ? -26.020 -21.853 -0.998  1.00 28.64  ? 455 TYR A OH     1 
ATOM   7197  H H      . TYR A 1 455 ? -29.658 -19.529 3.451   1.00 35.76  ? 455 TYR A H      1 
ATOM   7198  H HA     . TYR A 1 455 ? -31.328 -20.809 1.850   1.00 39.28  ? 455 TYR A HA     1 
ATOM   7199  H HB2    . TYR A 1 455 ? -29.583 -21.770 3.839   1.00 42.43  ? 455 TYR A HB2    1 
ATOM   7200  H HB3    . TYR A 1 455 ? -30.461 -22.739 2.935   1.00 42.43  ? 455 TYR A HB3    1 
ATOM   7201  H HD1    . TYR A 1 455 ? -30.129 -22.318 0.368   1.00 42.59  ? 455 TYR A HD1    1 
ATOM   7202  H HD2    . TYR A 1 455 ? -27.388 -21.427 3.138   1.00 39.71  ? 455 TYR A HD2    1 
ATOM   7203  H HE1    . TYR A 1 455 ? -28.501 -22.304 -1.254  1.00 38.99  ? 455 TYR A HE1    1 
ATOM   7204  H HE2    . TYR A 1 455 ? -25.752 -21.413 1.511   1.00 36.27  ? 455 TYR A HE2    1 
ATOM   7205  H HH     . TYR A 1 455 ? -26.367 -22.027 -1.743  1.00 34.37  ? 455 TYR A HH     1 
ATOM   7206  N N      . VAL A 1 456 ? -33.209 -21.721 3.129   1.00 45.22  ? 456 VAL A N      1 
ATOM   7207  C CA     . VAL A 1 456 ? -34.323 -22.218 3.923   1.00 49.97  ? 456 VAL A CA     1 
ATOM   7208  C C      . VAL A 1 456 ? -33.846 -23.430 4.722   1.00 51.88  ? 456 VAL A C      1 
ATOM   7209  O O      . VAL A 1 456 ? -32.982 -24.177 4.261   1.00 53.88  ? 456 VAL A O      1 
ATOM   7210  C CB     . VAL A 1 456 ? -35.529 -22.594 3.034   1.00 42.85  ? 456 VAL A CB     1 
ATOM   7211  C CG1    . VAL A 1 456 ? -35.889 -21.434 2.128   1.00 35.98  ? 456 VAL A CG1    1 
ATOM   7212  C CG2    . VAL A 1 456 ? -35.233 -23.837 2.198   1.00 43.59  ? 456 VAL A CG2    1 
ATOM   7213  H H      . VAL A 1 456 ? -33.253 -21.932 2.297   1.00 54.27  ? 456 VAL A H      1 
ATOM   7214  H HA     . VAL A 1 456 ? -34.607 -21.532 4.547   1.00 59.96  ? 456 VAL A HA     1 
ATOM   7215  H HB     . VAL A 1 456 ? -36.294 -22.785 3.599   1.00 51.42  ? 456 VAL A HB     1 
ATOM   7216  H HG11   . VAL A 1 456 ? -36.715 -21.642 1.664   1.00 43.17  ? 456 VAL A HG11   1 
ATOM   7217  H HG12   . VAL A 1 456 ? -36.004 -20.637 2.668   1.00 43.17  ? 456 VAL A HG12   1 
ATOM   7218  H HG13   . VAL A 1 456 ? -35.174 -21.299 1.487   1.00 43.17  ? 456 VAL A HG13   1 
ATOM   7219  H HG21   . VAL A 1 456 ? -35.893 -23.905 1.491   1.00 52.31  ? 456 VAL A HG21   1 
ATOM   7220  H HG22   . VAL A 1 456 ? -34.346 -23.756 1.815   1.00 52.31  ? 456 VAL A HG22   1 
ATOM   7221  H HG23   . VAL A 1 456 ? -35.277 -24.621 2.767   1.00 52.31  ? 456 VAL A HG23   1 
ATOM   7222  N N      . HIS A 1 457 ? -34.391 -23.612 5.922   1.00 56.98  ? 457 HIS A N      1 
ATOM   7223  C CA     . HIS A 1 457 ? -34.067 -24.775 6.747   1.00 64.20  ? 457 HIS A CA     1 
ATOM   7224  C C      . HIS A 1 457 ? -35.321 -25.271 7.456   1.00 63.63  ? 457 HIS A C      1 
ATOM   7225  O O      . HIS A 1 457 ? -36.404 -25.297 6.869   1.00 62.62  ? 457 HIS A O      1 
ATOM   7226  C CB     . HIS A 1 457 ? -32.973 -24.441 7.772   1.00 72.41  ? 457 HIS A CB     1 
ATOM   7227  C CG     . HIS A 1 457 ? -31.586 -24.402 7.197   1.00 75.31  ? 457 HIS A CG     1 
ATOM   7228  N ND1    . HIS A 1 457 ? -30.852 -25.542 6.945   1.00 73.15  ? 457 HIS A ND1    1 
ATOM   7229  C CD2    . HIS A 1 457 ? -30.795 -23.360 6.844   1.00 62.73  ? 457 HIS A CD2    1 
ATOM   7230  C CE1    . HIS A 1 457 ? -29.673 -25.204 6.451   1.00 67.02  ? 457 HIS A CE1    1 
ATOM   7231  N NE2    . HIS A 1 457 ? -29.613 -23.887 6.381   1.00 62.45  ? 457 HIS A NE2    1 
ATOM   7232  H H      . HIS A 1 457 ? -34.955 -23.073 6.284   1.00 68.38  ? 457 HIS A H      1 
ATOM   7233  H HA     . HIS A 1 457 ? -33.742 -25.494 6.183   1.00 77.04  ? 457 HIS A HA     1 
ATOM   7234  H HB2    . HIS A 1 457 ? -33.159 -23.569 8.154   1.00 86.89  ? 457 HIS A HB2    1 
ATOM   7235  H HB3    . HIS A 1 457 ? -32.985 -25.114 8.471   1.00 86.89  ? 457 HIS A HB3    1 
ATOM   7236  H HD2    . HIS A 1 457 ? -31.013 -22.458 6.900   1.00 75.27  ? 457 HIS A HD2    1 
ATOM   7237  H HE1    . HIS A 1 457 ? -29.000 -25.794 6.198   1.00 80.42  ? 457 HIS A HE1    1 
ATOM   7238  H HE2    . HIS A 1 457 ? -28.943 -23.432 6.091   1.00 74.94  ? 457 HIS A HE2    1 
ATOM   7239  N N      . MET B 1 1   ? 5.025   32.334  -9.439  1.00 117.01 ? 1   MET B N      1 
ATOM   7240  C CA     . MET B 1 1   ? 5.307   32.670  -10.812 1.00 91.87  ? 1   MET B CA     1 
ATOM   7241  C C      . MET B 1 1   ? 4.103   32.974  -11.655 1.00 71.18  ? 1   MET B C      1 
ATOM   7242  O O      . MET B 1 1   ? 3.124   32.258  -11.654 1.00 49.81  ? 1   MET B O      1 
ATOM   7243  C CB     . MET B 1 1   ? 6.018   31.503  -11.439 1.00 70.56  ? 1   MET B CB     1 
ATOM   7244  C CG     . MET B 1 1   ? 7.451   31.413  -11.053 1.00 65.38  ? 1   MET B CG     1 
ATOM   7245  S SD     . MET B 1 1   ? 8.201   30.426  -12.277 1.00 79.51  ? 1   MET B SD     1 
ATOM   7246  C CE     . MET B 1 1   ? 8.299   31.571  -13.624 1.00 50.30  ? 1   MET B CE     1 
ATOM   7247  H H1     . MET B 1 1   ? 5.787   32.158  -9.014  1.00 140.42 ? 1   MET B H1     1 
ATOM   7248  H H2     . MET B 1 1   ? 4.617   33.019  -9.044  1.00 140.42 ? 1   MET B H2     1 
ATOM   7249  H H3     . MET B 1 1   ? 4.497   31.618  -9.411  1.00 140.42 ? 1   MET B H3     1 
ATOM   7250  H HA     . MET B 1 1   ? 5.905   33.433  -10.832 1.00 110.24 ? 1   MET B HA     1 
ATOM   7251  H HB2    . MET B 1 1   ? 5.583   30.684  -11.156 1.00 84.68  ? 1   MET B HB2    1 
ATOM   7252  H HB3    . MET B 1 1   ? 5.964   31.587  -12.403 1.00 84.68  ? 1   MET B HB3    1 
ATOM   7253  H HG2    . MET B 1 1   ? 7.860   32.293  -11.053 1.00 78.46  ? 1   MET B HG2    1 
ATOM   7254  H HG3    . MET B 1 1   ? 7.542   30.980  -10.190 1.00 78.46  ? 1   MET B HG3    1 
ATOM   7255  H HE1    . MET B 1 1   ? 7.480   31.513  -14.138 1.00 60.36  ? 1   MET B HE1    1 
ATOM   7256  H HE2    . MET B 1 1   ? 8.410   32.468  -13.273 1.00 60.36  ? 1   MET B HE2    1 
ATOM   7257  H HE3    . MET B 1 1   ? 9.055   31.335  -14.184 1.00 60.36  ? 1   MET B HE3    1 
ATOM   7258  N N      . MET B 1 2   ? 4.254   34.009  -12.439 1.00 46.23  ? 2   MET B N      1 
ATOM   7259  C CA     . MET B 1 2   ? 3.219   34.396  -13.325 1.00 39.39  ? 2   MET B CA     1 
ATOM   7260  C C      . MET B 1 2   ? 2.954   33.247  -14.311 1.00 34.03  ? 2   MET B C      1 
ATOM   7261  O O      . MET B 1 2   ? 1.830   32.957  -14.635 1.00 27.80  ? 2   MET B O      1 
ATOM   7262  C CB     . MET B 1 2   ? 3.589   35.696  -14.039 1.00 27.37  ? 2   MET B CB     1 
ATOM   7263  C CG     . MET B 1 2   ? 2.419   36.589  -14.272 1.00 28.88  ? 2   MET B CG     1 
ATOM   7264  S SD     . MET B 1 2   ? 2.929   38.310  -14.231 1.00 77.31  ? 2   MET B SD     1 
ATOM   7265  C CE     . MET B 1 2   ? 4.171   38.333  -15.488 1.00 28.07  ? 2   MET B CE     1 
ATOM   7266  H H      . MET B 1 2   ? 4.957   34.503  -12.471 1.00 55.48  ? 2   MET B H      1 
ATOM   7267  H HA     . MET B 1 2   ? 2.414   34.553  -12.808 1.00 47.27  ? 2   MET B HA     1 
ATOM   7268  H HB2    . MET B 1 2   ? 4.231   36.182  -13.498 1.00 32.84  ? 2   MET B HB2    1 
ATOM   7269  H HB3    . MET B 1 2   ? 3.978   35.482  -14.902 1.00 32.84  ? 2   MET B HB3    1 
ATOM   7270  H HG2    . MET B 1 2   ? 2.039   36.402  -15.145 1.00 34.66  ? 2   MET B HG2    1 
ATOM   7271  H HG3    . MET B 1 2   ? 1.755   36.453  -13.578 1.00 34.66  ? 2   MET B HG3    1 
ATOM   7272  H HE1    . MET B 1 2   ? 4.453   39.249  -15.635 1.00 33.68  ? 2   MET B HE1    1 
ATOM   7273  H HE2    . MET B 1 2   ? 4.926   37.798  -15.198 1.00 33.68  ? 2   MET B HE2    1 
ATOM   7274  H HE3    . MET B 1 2   ? 3.799   37.967  -16.306 1.00 33.68  ? 2   MET B HE3    1 
ATOM   7275  N N      . TYR B 1 3   ? 4.015   32.628  -14.792 1.00 28.02  ? 3   TYR B N      1 
ATOM   7276  C CA     . TYR B 1 3   ? 3.886   31.574  -15.764 1.00 26.33  ? 3   TYR B CA     1 
ATOM   7277  C C      . TYR B 1 3   ? 4.814   30.415  -15.443 1.00 24.42  ? 3   TYR B C      1 
ATOM   7278  O O      . TYR B 1 3   ? 5.903   30.389  -15.895 1.00 24.07  ? 3   TYR B O      1 
ATOM   7279  C CB     . TYR B 1 3   ? 4.090   32.140  -17.151 1.00 22.53  ? 3   TYR B CB     1 
ATOM   7280  C CG     . TYR B 1 3   ? 3.152   33.256  -17.464 1.00 23.54  ? 3   TYR B CG     1 
ATOM   7281  C CD1    . TYR B 1 3   ? 1.810   33.062  -17.481 1.00 20.97  ? 3   TYR B CD1    1 
ATOM   7282  C CD2    . TYR B 1 3   ? 3.611   34.505  -17.695 1.00 23.34  ? 3   TYR B CD2    1 
ATOM   7283  C CE1    . TYR B 1 3   ? 0.954   34.089  -17.740 1.00 24.27  ? 3   TYR B CE1    1 
ATOM   7284  C CE2    . TYR B 1 3   ? 2.769   35.522  -17.962 1.00 25.24  ? 3   TYR B CE2    1 
ATOM   7285  C CZ     . TYR B 1 3   ? 1.438   35.311  -17.984 1.00 27.48  ? 3   TYR B CZ     1 
ATOM   7286  O OH     . TYR B 1 3   ? 0.614   36.348  -18.240 1.00 31.39  ? 3   TYR B OH     1 
ATOM   7287  H H      . TYR B 1 3   ? 4.826   32.804  -14.567 1.00 33.62  ? 3   TYR B H      1 
ATOM   7288  H HA     . TYR B 1 3   ? 2.982   31.230  -15.745 1.00 31.59  ? 3   TYR B HA     1 
ATOM   7289  H HB2    . TYR B 1 3   ? 4.995   32.481  -17.223 1.00 27.03  ? 3   TYR B HB2    1 
ATOM   7290  H HB3    . TYR B 1 3   ? 3.947   31.436  -17.803 1.00 27.03  ? 3   TYR B HB3    1 
ATOM   7291  H HD1    . TYR B 1 3   ? 1.469   32.213  -17.313 1.00 25.16  ? 3   TYR B HD1    1 
ATOM   7292  H HD2    . TYR B 1 3   ? 4.527   34.663  -17.684 1.00 28.00  ? 3   TYR B HD2    1 
ATOM   7293  H HE1    . TYR B 1 3   ? 0.036   33.939  -17.756 1.00 29.12  ? 3   TYR B HE1    1 
ATOM   7294  H HE2    . TYR B 1 3   ? 3.106   36.373  -18.124 1.00 30.29  ? 3   TYR B HE2    1 
ATOM   7295  H HH     . TYR B 1 3   ? 1.063   37.046  -18.372 1.00 37.67  ? 3   TYR B HH     1 
ATOM   7296  N N      . PRO B 1 4   ? 4.367   29.476  -14.633 1.00 21.24  ? 4   PRO B N      1 
ATOM   7297  C CA     . PRO B 1 4   ? 5.268   28.399  -14.213 1.00 19.65  ? 4   PRO B CA     1 
ATOM   7298  C C      . PRO B 1 4   ? 5.501   27.363  -15.305 1.00 20.44  ? 4   PRO B C      1 
ATOM   7299  O O      . PRO B 1 4   ? 4.689   27.223  -16.216 1.00 18.23  ? 4   PRO B O      1 
ATOM   7300  C CB     . PRO B 1 4   ? 4.531   27.776  -13.027 1.00 25.42  ? 4   PRO B CB     1 
ATOM   7301  C CG     . PRO B 1 4   ? 3.092   28.013  -13.323 1.00 20.15  ? 4   PRO B CG     1 
ATOM   7302  C CD     . PRO B 1 4   ? 3.019   29.324  -14.059 1.00 21.03  ? 4   PRO B CD     1 
ATOM   7303  H HA     . PRO B 1 4   ? 6.118   28.758  -13.915 1.00 23.58  ? 4   PRO B HA     1 
ATOM   7304  H HB2    . PRO B 1 4   ? 4.723   26.826  -12.982 1.00 30.51  ? 4   PRO B HB2    1 
ATOM   7305  H HB3    . PRO B 1 4   ? 4.793   28.221  -12.206 1.00 30.51  ? 4   PRO B HB3    1 
ATOM   7306  H HG2    . PRO B 1 4   ? 2.754   27.293  -13.878 1.00 24.18  ? 4   PRO B HG2    1 
ATOM   7307  H HG3    . PRO B 1 4   ? 2.595   28.063  -12.491 1.00 24.18  ? 4   PRO B HG3    1 
ATOM   7308  H HD2    . PRO B 1 4   ? 2.355   29.277  -14.764 1.00 25.24  ? 4   PRO B HD2    1 
ATOM   7309  H HD3    . PRO B 1 4   ? 2.831   30.048  -13.441 1.00 25.24  ? 4   PRO B HD3    1 
ATOM   7310  N N      . ALA B 1 5   ? 6.606   26.636  -15.197 1.00 18.89  ? 5   ALA B N      1 
ATOM   7311  C CA     . ALA B 1 5   ? 6.900   25.552  -16.113 1.00 20.15  ? 5   ALA B CA     1 
ATOM   7312  C C      . ALA B 1 5   ? 5.942   24.393  -15.860 1.00 17.88  ? 5   ALA B C      1 
ATOM   7313  O O      . ALA B 1 5   ? 5.316   24.312  -14.798 1.00 17.35  ? 5   ALA B O      1 
ATOM   7314  C CB     . ALA B 1 5   ? 8.344   25.099  -15.950 1.00 19.44  ? 5   ALA B CB     1 
ATOM   7315  H H      . ALA B 1 5   ? 7.206   26.755  -14.593 1.00 22.67  ? 5   ALA B H      1 
ATOM   7316  H HA     . ALA B 1 5   ? 6.776   25.858  -17.025 1.00 24.18  ? 5   ALA B HA     1 
ATOM   7317  H HB1    . ALA B 1 5   ? 8.519   24.375  -16.571 1.00 23.33  ? 5   ALA B HB1    1 
ATOM   7318  H HB2    . ALA B 1 5   ? 8.932   25.847  -16.139 1.00 23.33  ? 5   ALA B HB2    1 
ATOM   7319  H HB3    . ALA B 1 5   ? 8.478   24.794  -15.039 1.00 23.33  ? 5   ALA B HB3    1 
ATOM   7320  N N      . GLU B 1 6   ? 5.831   23.500  -16.836 1.00 17.03  ? 6   GLU B N      1 
ATOM   7321  C CA     . GLU B 1 6   ? 5.001   22.309  -16.694 1.00 17.02  ? 6   GLU B CA     1 
ATOM   7322  C C      . GLU B 1 6   ? 5.452   21.456  -15.516 1.00 16.85  ? 6   GLU B C      1 
ATOM   7323  O O      . GLU B 1 6   ? 6.630   21.076  -15.439 1.00 19.02  ? 6   GLU B O      1 
ATOM   7324  C CB     . GLU B 1 6   ? 5.035   21.460  -17.964 1.00 19.95  ? 6   GLU B CB     1 
ATOM   7325  C CG     . GLU B 1 6   ? 4.473   22.148  -19.184 1.00 17.01  ? 6   GLU B CG     1 
ATOM   7326  C CD     . GLU B 1 6   ? 5.488   22.985  -19.936 1.00 22.30  ? 6   GLU B CD     1 
ATOM   7327  O OE1    . GLU B 1 6   ? 6.671   23.037  -19.520 1.00 20.12  ? 6   GLU B OE1    1 
ATOM   7328  O OE2    . GLU B 1 6   ? 5.094   23.596  -20.953 1.00 23.60  ? 6   GLU B OE2    1 
ATOM   7329  H H      . GLU B 1 6   ? 6.231   23.560  -17.594 1.00 20.43  ? 6   GLU B H      1 
ATOM   7330  H HA     . GLU B 1 6   ? 4.087   22.596  -16.563 1.00 20.43  ? 6   GLU B HA     1 
ATOM   7331  H HB2    . GLU B 1 6   ? 5.951   21.202  -18.148 1.00 23.95  ? 6   GLU B HB2    1 
ATOM   7332  H HB3    . GLU B 1 6   ? 4.503   20.664  -17.811 1.00 23.95  ? 6   GLU B HB3    1 
ATOM   7333  H HG2    . GLU B 1 6   ? 4.133   21.475  -19.794 1.00 20.41  ? 6   GLU B HG2    1 
ATOM   7334  H HG3    . GLU B 1 6   ? 3.752   22.734  -18.907 1.00 20.41  ? 6   GLU B HG3    1 
ATOM   7335  N N      . PRO B 1 7   ? 4.520   21.139  -14.594 1.00 18.21  ? 7   PRO B N      1 
ATOM   7336  C CA     . PRO B 1 7   ? 4.854   20.316  -13.424 1.00 17.06  ? 7   PRO B CA     1 
ATOM   7337  C C      . PRO B 1 7   ? 4.818   18.819  -13.738 1.00 18.66  ? 7   PRO B C      1 
ATOM   7338  O O      . PRO B 1 7   ? 4.260   18.021  -12.985 1.00 15.60  ? 7   PRO B O      1 
ATOM   7339  C CB     . PRO B 1 7   ? 3.768   20.701  -12.423 1.00 18.67  ? 7   PRO B CB     1 
ATOM   7340  C CG     . PRO B 1 7   ? 2.571   20.899  -13.287 1.00 17.18  ? 7   PRO B CG     1 
ATOM   7341  C CD     . PRO B 1 7   ? 3.115   21.589  -14.542 1.00 20.48  ? 7   PRO B CD     1 
ATOM   7342  H HA     . PRO B 1 7   ? 5.724   20.557  -13.070 1.00 20.47  ? 7   PRO B HA     1 
ATOM   7343  H HB2    . PRO B 1 7   ? 3.624   19.993  -11.777 1.00 22.41  ? 7   PRO B HB2    1 
ATOM   7344  H HB3    . PRO B 1 7   ? 4.011   21.528  -11.978 1.00 22.41  ? 7   PRO B HB3    1 
ATOM   7345  H HG2    . PRO B 1 7   ? 2.179   20.040  -13.508 1.00 20.62  ? 7   PRO B HG2    1 
ATOM   7346  H HG3    . PRO B 1 7   ? 1.928   21.465  -12.833 1.00 20.62  ? 7   PRO B HG3    1 
ATOM   7347  H HD2    . PRO B 1 7   ? 2.633   21.289  -15.329 1.00 24.58  ? 7   PRO B HD2    1 
ATOM   7348  H HD3    . PRO B 1 7   ? 3.072   22.553  -14.443 1.00 24.58  ? 7   PRO B HD3    1 
ATOM   7349  N N      . TYR B 1 8   ? 5.439   18.461  -14.854 1.00 15.03  ? 8   TYR B N      1 
ATOM   7350  C CA     . TYR B 1 8   ? 5.484   17.087  -15.346 1.00 14.76  ? 8   TYR B CA     1 
ATOM   7351  C C      . TYR B 1 8   ? 6.464   17.066  -16.502 1.00 17.01  ? 8   TYR B C      1 
ATOM   7352  O O      . TYR B 1 8   ? 6.868   18.129  -16.985 1.00 16.54  ? 8   TYR B O      1 
ATOM   7353  C CB     . TYR B 1 8   ? 4.103   16.587  -15.798 1.00 16.74  ? 8   TYR B CB     1 
ATOM   7354  C CG     . TYR B 1 8   ? 3.323   17.561  -16.668 1.00 16.01  ? 8   TYR B CG     1 
ATOM   7355  C CD1    . TYR B 1 8   ? 3.613   17.719  -18.019 1.00 14.77  ? 8   TYR B CD1    1 
ATOM   7356  C CD2    . TYR B 1 8   ? 2.283   18.322  -16.125 1.00 19.13  ? 8   TYR B CD2    1 
ATOM   7357  C CE1    . TYR B 1 8   ? 2.892   18.625  -18.807 1.00 16.70  ? 8   TYR B CE1    1 
ATOM   7358  C CE2    . TYR B 1 8   ? 1.567   19.217  -16.901 1.00 18.07  ? 8   TYR B CE2    1 
ATOM   7359  C CZ     . TYR B 1 8   ? 1.870   19.359  -18.231 1.00 17.92  ? 8   TYR B CZ     1 
ATOM   7360  O OH     . TYR B 1 8   ? 1.146   20.255  -18.975 1.00 20.58  ? 8   TYR B OH     1 
ATOM   7361  H H      . TYR B 1 8   ? 5.860   19.012  -15.361 1.00 18.03  ? 8   TYR B H      1 
ATOM   7362  H HA     . TYR B 1 8   ? 5.814   16.500  -14.648 1.00 17.71  ? 8   TYR B HA     1 
ATOM   7363  H HB2    . TYR B 1 8   ? 4.222   15.770  -16.307 1.00 20.09  ? 8   TYR B HB2    1 
ATOM   7364  H HB3    . TYR B 1 8   ? 3.567   16.405  -15.010 1.00 20.09  ? 8   TYR B HB3    1 
ATOM   7365  H HD1    . TYR B 1 8   ? 4.301   17.224  -18.402 1.00 17.73  ? 8   TYR B HD1    1 
ATOM   7366  H HD2    . TYR B 1 8   ? 2.074   18.231  -15.224 1.00 22.96  ? 8   TYR B HD2    1 
ATOM   7367  H HE1    . TYR B 1 8   ? 3.093   18.726  -19.709 1.00 20.04  ? 8   TYR B HE1    1 
ATOM   7368  H HE2    . TYR B 1 8   ? 0.880   19.717  -16.523 1.00 21.68  ? 8   TYR B HE2    1 
ATOM   7369  H HH     . TYR B 1 8   ? 1.425   20.262  -19.767 1.00 24.70  ? 8   TYR B HH     1 
ATOM   7370  N N      . ARG B 1 9   ? 6.857   15.865  -16.925 1.00 14.58  ? 9   ARG B N      1 
ATOM   7371  C CA     . ARG B 1 9   ? 7.641   15.690  -18.140 1.00 16.50  ? 9   ARG B CA     1 
ATOM   7372  C C      . ARG B 1 9   ? 6.775   15.100  -19.242 1.00 16.20  ? 9   ARG B C      1 
ATOM   7373  O O      . ARG B 1 9   ? 5.678   14.605  -18.997 1.00 17.39  ? 9   ARG B O      1 
ATOM   7374  C CB     . ARG B 1 9   ? 8.833   14.756  -17.913 1.00 16.19  ? 9   ARG B CB     1 
ATOM   7375  C CG     . ARG B 1 9   ? 9.547   14.926  -16.619 1.00 19.24  ? 9   ARG B CG     1 
ATOM   7376  C CD     . ARG B 1 9   ? 10.632  13.881  -16.494 1.00 21.97  ? 9   ARG B CD     1 
ATOM   7377  N NE     . ARG B 1 9   ? 11.344  13.991  -15.228 1.00 18.76  ? 9   ARG B NE     1 
ATOM   7378  C CZ     . ARG B 1 9   ? 12.224  13.100  -14.793 1.00 20.82  ? 9   ARG B CZ     1 
ATOM   7379  N NH1    . ARG B 1 9   ? 12.487  12.020  -15.521 1.00 19.82  ? 9   ARG B NH1    1 
ATOM   7380  N NH2    . ARG B 1 9   ? 12.832  13.281  -13.625 1.00 21.12  ? 9   ARG B NH2    1 
ATOM   7381  H H      . ARG B 1 9   ? 6.678   15.129  -16.518 1.00 17.49  ? 9   ARG B H      1 
ATOM   7382  H HA     . ARG B 1 9   ? 7.981   16.545  -18.444 1.00 19.81  ? 9   ARG B HA     1 
ATOM   7383  H HB2    . ARG B 1 9   ? 8.517   13.840  -17.953 1.00 19.43  ? 9   ARG B HB2    1 
ATOM   7384  H HB3    . ARG B 1 9   ? 9.478   14.906  -18.622 1.00 19.43  ? 9   ARG B HB3    1 
ATOM   7385  H HG2    . ARG B 1 9   ? 9.957   15.804  -16.586 1.00 23.09  ? 9   ARG B HG2    1 
ATOM   7386  H HG3    . ARG B 1 9   ? 8.926   14.811  -15.883 1.00 23.09  ? 9   ARG B HG3    1 
ATOM   7387  H HD2    . ARG B 1 9   ? 10.232  12.999  -16.541 1.00 26.36  ? 9   ARG B HD2    1 
ATOM   7388  H HD3    . ARG B 1 9   ? 11.272  13.997  -17.213 1.00 26.36  ? 9   ARG B HD3    1 
ATOM   7389  H HE     . ARG B 1 9   ? 11.131  14.636  -14.701 1.00 22.51  ? 9   ARG B HE     1 
ATOM   7390  H HH11   . ARG B 1 9   ? 12.096  11.900  -16.277 1.00 23.78  ? 9   ARG B HH11   1 
ATOM   7391  H HH12   . ARG B 1 9   ? 13.056  11.441  -15.237 1.00 23.78  ? 9   ARG B HH12   1 
ATOM   7392  H HH21   . ARG B 1 9   ? 12.658  13.979  -13.153 1.00 25.34  ? 9   ARG B HH21   1 
ATOM   7393  H HH22   . ARG B 1 9   ? 13.399  12.700  -13.341 1.00 25.34  ? 9   ARG B HH22   1 
ATOM   7394  N N      . ILE B 1 10  ? 7.289   15.135  -20.457 1.00 14.37  ? 10  ILE B N      1 
ATOM   7395  C CA     . ILE B 1 10  ? 6.639   14.460  -21.559 1.00 14.25  ? 10  ILE B CA     1 
ATOM   7396  C C      . ILE B 1 10  ? 7.049   12.988  -21.526 1.00 16.58  ? 10  ILE B C      1 
ATOM   7397  O O      . ILE B 1 10  ? 8.247   12.664  -21.555 1.00 16.00  ? 10  ILE B O      1 
ATOM   7398  C CB     . ILE B 1 10  ? 7.014   15.103  -22.894 1.00 14.40  ? 10  ILE B CB     1 
ATOM   7399  C CG1    . ILE B 1 10  ? 6.553   16.564  -22.901 1.00 17.71  ? 10  ILE B CG1    1 
ATOM   7400  C CG2    . ILE B 1 10  ? 6.392   14.330  -24.060 1.00 17.30  ? 10  ILE B CG2    1 
ATOM   7401  C CD1    . ILE B 1 10  ? 7.030   17.359  -24.117 1.00 19.55  ? 10  ILE B CD1    1 
ATOM   7402  H H      . ILE B 1 10  ? 8.015   15.544  -20.670 1.00 17.24  ? 10  ILE B H      1 
ATOM   7403  H HA     . ILE B 1 10  ? 5.676   14.514  -21.458 1.00 17.10  ? 10  ILE B HA     1 
ATOM   7404  H HB     . ILE B 1 10  ? 7.979   15.082  -22.988 1.00 17.29  ? 10  ILE B HB     1 
ATOM   7405  H HG12   . ILE B 1 10  ? 5.584   16.586  -22.888 1.00 21.25  ? 10  ILE B HG12   1 
ATOM   7406  H HG13   . ILE B 1 10  ? 6.899   17.006  -22.111 1.00 21.25  ? 10  ILE B HG13   1 
ATOM   7407  H HG21   . ILE B 1 10  ? 6.525   14.829  -24.880 1.00 20.76  ? 10  ILE B HG21   1 
ATOM   7408  H HG22   . ILE B 1 10  ? 6.820   13.463  -24.133 1.00 20.76  ? 10  ILE B HG22   1 
ATOM   7409  H HG23   . ILE B 1 10  ? 5.443   14.218  -23.893 1.00 20.76  ? 10  ILE B HG23   1 
ATOM   7410  H HD11   . ILE B 1 10  ? 6.905   18.305  -23.945 1.00 23.46  ? 10  ILE B HD11   1 
ATOM   7411  H HD12   . ILE B 1 10  ? 7.969   17.169  -24.262 1.00 23.46  ? 10  ILE B HD12   1 
ATOM   7412  H HD13   . ILE B 1 10  ? 6.514   17.091  -24.894 1.00 23.46  ? 10  ILE B HD13   1 
ATOM   7413  N N      . LYS B 1 11  ? 6.058   12.101  -21.433 1.00 15.13  ? 11  LYS B N      1 
ATOM   7414  C CA     . LYS B 1 11  ? 6.323   10.661  -21.469 1.00 15.53  ? 11  LYS B CA     1 
ATOM   7415  C C      . LYS B 1 11  ? 6.291   10.160  -22.903 1.00 14.78  ? 11  LYS B C      1 
ATOM   7416  O O      . LYS B 1 11  ? 7.146   9.377   -23.311 1.00 16.60  ? 11  LYS B O      1 
ATOM   7417  C CB     . LYS B 1 11  ? 5.310   9.881   -20.622 1.00 13.54  ? 11  LYS B CB     1 
ATOM   7418  C CG     . LYS B 1 11  ? 5.536   8.350   -20.610 1.00 18.23  ? 11  LYS B CG     1 
ATOM   7419  C CD     . LYS B 1 11  ? 6.914   7.997   -20.075 1.00 16.58  ? 11  LYS B CD     1 
ATOM   7420  C CE     . LYS B 1 11  ? 7.166   6.491   -20.056 1.00 23.15  ? 11  LYS B CE     1 
ATOM   7421  N NZ     . LYS B 1 11  ? 6.201   5.763   -19.191 1.00 22.49  ? 11  LYS B NZ     1 
ATOM   7422  H H      . LYS B 1 11  ? 5.227   12.305  -21.349 1.00 18.15  ? 11  LYS B H      1 
ATOM   7423  H HA     . LYS B 1 11  ? 7.207   10.493  -21.110 1.00 18.64  ? 11  LYS B HA     1 
ATOM   7424  H HB2    . LYS B 1 11  ? 5.364   10.194  -19.706 1.00 16.24  ? 11  LYS B HB2    1 
ATOM   7425  H HB3    . LYS B 1 11  ? 4.421   10.046  -20.971 1.00 16.24  ? 11  LYS B HB3    1 
ATOM   7426  H HG2    . LYS B 1 11  ? 4.873   7.935   -20.036 1.00 21.88  ? 11  LYS B HG2    1 
ATOM   7427  H HG3    . LYS B 1 11  ? 5.461   8.004   -21.513 1.00 21.88  ? 11  LYS B HG3    1 
ATOM   7428  H HD2    . LYS B 1 11  ? 7.591   8.400   -20.640 1.00 19.90  ? 11  LYS B HD2    1 
ATOM   7429  H HD3    . LYS B 1 11  ? 6.997   8.328   -19.167 1.00 19.90  ? 11  LYS B HD3    1 
ATOM   7430  H HE2    . LYS B 1 11  ? 7.082   6.144   -20.958 1.00 27.78  ? 11  LYS B HE2    1 
ATOM   7431  H HE3    . LYS B 1 11  ? 8.059   6.324   -19.717 1.00 27.78  ? 11  LYS B HE3    1 
ATOM   7432  H HZ1    . LYS B 1 11  ? 6.253   6.066   -18.356 1.00 26.99  ? 11  LYS B HZ1    1 
ATOM   7433  H HZ2    . LYS B 1 11  ? 5.372   5.884   -19.492 1.00 26.99  ? 11  LYS B HZ2    1 
ATOM   7434  H HZ3    . LYS B 1 11  ? 6.386   4.893   -19.195 1.00 26.99  ? 11  LYS B HZ3    1 
ATOM   7435  N N      . SER B 1 12  ? 5.301   10.610  -23.670 1.00 13.89  ? 12  SER B N      1 
ATOM   7436  C CA     . SER B 1 12  ? 5.215   10.221  -25.076 1.00 14.15  ? 12  SER B CA     1 
ATOM   7437  C C      . SER B 1 12  ? 4.603   11.348  -25.883 1.00 16.29  ? 12  SER B C      1 
ATOM   7438  O O      . SER B 1 12  ? 3.854   12.177  -25.345 1.00 14.83  ? 12  SER B O      1 
ATOM   7439  C CB     . SER B 1 12  ? 4.398   8.939   -25.250 1.00 16.67  ? 12  SER B CB     1 
ATOM   7440  O OG     . SER B 1 12  ? 3.028   9.154   -24.971 1.00 17.98  ? 12  SER B OG     1 
ATOM   7441  H H      . SER B 1 12  ? 4.674   11.135  -23.405 1.00 16.67  ? 12  SER B H      1 
ATOM   7442  H HA     . SER B 1 12  ? 6.109   10.066  -25.411 1.00 16.98  ? 12  SER B HA     1 
ATOM   7443  H HB2    . SER B 1 12  ? 4.487   8.632   -26.166 1.00 20.00  ? 12  SER B HB2    1 
ATOM   7444  H HB3    . SER B 1 12  ? 4.740   8.265   -24.642 1.00 20.00  ? 12  SER B HB3    1 
ATOM   7445  H HG     . SER B 1 12  ? 2.599   8.439   -25.072 1.00 21.58  ? 12  SER B HG     1 
ATOM   7446  N N      . VAL B 1 13  ? 4.941   11.396  -27.169 1.00 15.32  ? 13  VAL B N      1 
ATOM   7447  C CA     . VAL B 1 13  ? 4.454   12.457  -28.041 1.00 15.26  ? 13  VAL B CA     1 
ATOM   7448  C C      . VAL B 1 13  ? 3.478   11.927  -29.082 1.00 18.08  ? 13  VAL B C      1 
ATOM   7449  O O      . VAL B 1 13  ? 3.462   10.736  -29.397 1.00 17.56  ? 13  VAL B O      1 
ATOM   7450  C CB     . VAL B 1 13  ? 5.610   13.190  -28.778 1.00 12.18  ? 13  VAL B CB     1 
ATOM   7451  C CG1    . VAL B 1 13  ? 6.599   13.749  -27.778 1.00 16.98  ? 13  VAL B CG1    1 
ATOM   7452  C CG2    . VAL B 1 13  ? 6.320   12.277  -29.803 1.00 15.63  ? 13  VAL B CG2    1 
ATOM   7453  H H      . VAL B 1 13  ? 5.452   10.825  -27.560 1.00 18.39  ? 13  VAL B H      1 
ATOM   7454  H HA     . VAL B 1 13  ? 3.984   13.121  -27.514 1.00 18.32  ? 13  VAL B HA     1 
ATOM   7455  H HB     . VAL B 1 13  ? 5.236   13.940  -29.267 1.00 14.62  ? 13  VAL B HB     1 
ATOM   7456  H HG11   . VAL B 1 13  ? 7.283   14.245  -28.255 1.00 20.38  ? 13  VAL B HG11   1 
ATOM   7457  H HG12   . VAL B 1 13  ? 6.130   14.337  -27.166 1.00 20.38  ? 13  VAL B HG12   1 
ATOM   7458  H HG13   . VAL B 1 13  ? 7.003   13.015  -27.288 1.00 20.38  ? 13  VAL B HG13   1 
ATOM   7459  H HG21   . VAL B 1 13  ? 7.115   12.728  -30.127 1.00 18.75  ? 13  VAL B HG21   1 
ATOM   7460  H HG22   . VAL B 1 13  ? 6.567   11.447  -29.367 1.00 18.75  ? 13  VAL B HG22   1 
ATOM   7461  H HG23   . VAL B 1 13  ? 5.718   12.097  -30.542 1.00 18.75  ? 13  VAL B HG23   1 
ATOM   7462  N N      . GLU B 1 14  ? 2.644   12.832  -29.579 1.00 15.28  ? 14  GLU B N      1 
ATOM   7463  C CA     . GLU B 1 14  ? 1.777   12.566  -30.716 1.00 19.52  ? 14  GLU B CA     1 
ATOM   7464  C C      . GLU B 1 14  ? 2.412   13.239  -31.917 1.00 23.17  ? 14  GLU B C      1 
ATOM   7465  O O      . GLU B 1 14  ? 2.513   14.459  -31.966 1.00 19.77  ? 14  GLU B O      1 
ATOM   7466  C CB     . GLU B 1 14  ? 0.364   13.100  -30.451 1.00 21.97  ? 14  GLU B CB     1 
ATOM   7467  C CG     . GLU B 1 14  ? -0.705  12.623  -31.408 1.00 29.96  ? 14  GLU B CG     1 
ATOM   7468  C CD     . GLU B 1 14  ? -2.082  13.178  -31.057 1.00 39.21  ? 14  GLU B CD     1 
ATOM   7469  O OE1    . GLU B 1 14  ? -2.237  13.747  -29.952 1.00 42.76  ? 14  GLU B OE1    1 
ATOM   7470  O OE2    . GLU B 1 14  ? -3.008  13.061  -31.889 1.00 37.38  ? 14  GLU B OE2    1 
ATOM   7471  H H      . GLU B 1 14  ? 2.561   13.628  -29.265 1.00 18.34  ? 14  GLU B H      1 
ATOM   7472  H HA     . GLU B 1 14  ? 1.722   11.613  -30.884 1.00 23.43  ? 14  GLU B HA     1 
ATOM   7473  H HB2    . GLU B 1 14  ? 0.099   12.827  -29.559 1.00 26.36  ? 14  GLU B HB2    1 
ATOM   7474  H HB3    . GLU B 1 14  ? 0.387   14.068  -30.499 1.00 26.36  ? 14  GLU B HB3    1 
ATOM   7475  H HG2    . GLU B 1 14  ? -0.482  12.915  -32.306 1.00 35.95  ? 14  GLU B HG2    1 
ATOM   7476  H HG3    . GLU B 1 14  ? -0.753  11.655  -31.374 1.00 35.95  ? 14  GLU B HG3    1 
ATOM   7477  N N      . THR B 1 15  ? 2.890   12.460  -32.878 1.00 23.01  ? 15  THR B N      1 
ATOM   7478  C CA     . THR B 1 15  ? 3.561   13.068  -34.018 1.00 22.86  ? 15  THR B CA     1 
ATOM   7479  C C      . THR B 1 15  ? 2.526   13.813  -34.857 1.00 18.86  ? 15  THR B C      1 
ATOM   7480  O O      . THR B 1 15  ? 1.339   13.485  -34.837 1.00 24.10  ? 15  THR B O      1 
ATOM   7481  C CB     . THR B 1 15  ? 4.303   12.023  -34.878 1.00 32.26  ? 15  THR B CB     1 
ATOM   7482  O OG1    . THR B 1 15  ? 3.501   10.844  -34.972 1.00 31.50  ? 15  THR B OG1    1 
ATOM   7483  C CG2    . THR B 1 15  ? 5.668   11.670  -34.240 1.00 35.02  ? 15  THR B CG2    1 
ATOM   7484  H H      . THR B 1 15  ? 2.842   11.602  -32.896 1.00 27.61  ? 15  THR B H      1 
ATOM   7485  H HA     . THR B 1 15  ? 4.213   13.712  -33.700 1.00 27.44  ? 15  THR B HA     1 
ATOM   7486  H HB     . THR B 1 15  ? 4.459   12.383  -35.765 1.00 38.71  ? 15  THR B HB     1 
ATOM   7487  H HG1    . THR B 1 15  ? 3.894   10.266  -35.438 1.00 37.80  ? 15  THR B HG1    1 
ATOM   7488  H HG21   . THR B 1 15  ? 6.128   11.013  -34.785 1.00 42.02  ? 15  THR B HG21   1 
ATOM   7489  H HG22   . THR B 1 15  ? 6.218   12.466  -34.174 1.00 42.02  ? 15  THR B HG22   1 
ATOM   7490  H HG23   . THR B 1 15  ? 5.534   11.305  -33.352 1.00 42.02  ? 15  THR B HG23   1 
ATOM   7491  N N      . VAL B 1 16  ? 2.988   14.849  -35.547 1.00 22.51  ? 16  VAL B N      1 
ATOM   7492  C CA     . VAL B 1 16  ? 2.133   15.657  -36.420 1.00 25.80  ? 16  VAL B CA     1 
ATOM   7493  C C      . VAL B 1 16  ? 2.845   15.822  -37.766 1.00 23.45  ? 16  VAL B C      1 
ATOM   7494  O O      . VAL B 1 16  ? 4.067   15.778  -37.828 1.00 26.25  ? 16  VAL B O      1 
ATOM   7495  C CB     . VAL B 1 16  ? 1.835   17.068  -35.828 1.00 26.61  ? 16  VAL B CB     1 
ATOM   7496  C CG1    . VAL B 1 16  ? 1.237   16.987  -34.438 1.00 23.81  ? 16  VAL B CG1    1 
ATOM   7497  C CG2    . VAL B 1 16  ? 3.076   17.870  -35.780 1.00 24.35  ? 16  VAL B CG2    1 
ATOM   7498  H H      . VAL B 1 16  ? 3.807   15.111  -35.528 1.00 27.01  ? 16  VAL B H      1 
ATOM   7499  H HA     . VAL B 1 16  ? 1.290   15.204  -36.575 1.00 30.96  ? 16  VAL B HA     1 
ATOM   7500  H HB     . VAL B 1 16  ? 1.202   17.526  -36.402 1.00 31.93  ? 16  VAL B HB     1 
ATOM   7501  H HG11   . VAL B 1 16  ? 1.012   17.882  -34.138 1.00 28.57  ? 16  VAL B HG11   1 
ATOM   7502  H HG12   . VAL B 1 16  ? 0.438   16.438  -34.470 1.00 28.57  ? 16  VAL B HG12   1 
ATOM   7503  H HG13   . VAL B 1 16  ? 1.887   16.590  -33.837 1.00 28.57  ? 16  VAL B HG13   1 
ATOM   7504  H HG21   . VAL B 1 16  ? 2.959   18.594  -35.145 1.00 29.22  ? 16  VAL B HG21   1 
ATOM   7505  H HG22   . VAL B 1 16  ? 3.809   17.301  -35.501 1.00 29.22  ? 16  VAL B HG22   1 
ATOM   7506  H HG23   . VAL B 1 16  ? 3.256   18.231  -36.662 1.00 29.22  ? 16  VAL B HG23   1 
ATOM   7507  N N      . SER B 1 17  ? 2.097   16.086  -38.830 1.00 28.46  ? 17  SER B N      1 
ATOM   7508  C CA     . SER B 1 17  ? 2.699   16.134  -40.164 1.00 26.59  ? 17  SER B CA     1 
ATOM   7509  C C      . SER B 1 17  ? 3.444   17.449  -40.541 1.00 29.91  ? 17  SER B C      1 
ATOM   7510  O O      . SER B 1 17  ? 4.336   17.420  -41.384 1.00 41.87  ? 17  SER B O      1 
ATOM   7511  C CB     . SER B 1 17  ? 1.612   15.834  -41.200 1.00 35.67  ? 17  SER B CB     1 
ATOM   7512  O OG     . SER B 1 17  ? 0.434   16.570  -40.924 1.00 43.57  ? 17  SER B OG     1 
ATOM   7513  H H      . SER B 1 17  ? 1.251   16.239  -38.812 1.00 34.15  ? 17  SER B H      1 
ATOM   7514  H HA     . SER B 1 17  ? 3.349   15.417  -40.224 1.00 31.91  ? 17  SER B HA     1 
ATOM   7515  H HB2    . SER B 1 17  ? 1.938   16.079  -42.080 1.00 42.80  ? 17  SER B HB2    1 
ATOM   7516  H HB3    . SER B 1 17  ? 1.405   14.887  -41.175 1.00 42.80  ? 17  SER B HB3    1 
ATOM   7517  H HG     . SER B 1 17  ? -0.154  16.397  -41.498 1.00 52.29  ? 17  SER B HG     1 
ATOM   7518  N N      . MET B 1 18  ? 3.106   18.581  -39.933 1.00 33.66  ? 18  MET B N      1 
ATOM   7519  C CA     . MET B 1 18  ? 3.832   19.848  -40.192 1.00 31.00  ? 18  MET B CA     1 
ATOM   7520  C C      . MET B 1 18  ? 3.774   20.245  -41.669 1.00 27.82  ? 18  MET B C      1 
ATOM   7521  O O      . MET B 1 18  ? 4.801   20.508  -42.294 1.00 32.96  ? 18  MET B O      1 
ATOM   7522  C CB     . MET B 1 18  ? 5.311   19.765  -39.777 1.00 34.63  ? 18  MET B CB     1 
ATOM   7523  C CG     . MET B 1 18  ? 5.585   19.427  -38.318 1.00 32.68  ? 18  MET B CG     1 
ATOM   7524  S SD     . MET B 1 18  ? 4.867   20.599  -37.160 1.00 27.57  ? 18  MET B SD     1 
ATOM   7525  C CE     . MET B 1 18  ? 5.778   22.097  -37.536 1.00 26.53  ? 18  MET B CE     1 
ATOM   7526  H H      . MET B 1 18  ? 2.464   18.654  -39.366 1.00 40.39  ? 18  MET B H      1 
ATOM   7527  H HA     . MET B 1 18  ? 3.419   20.552  -39.667 1.00 37.19  ? 18  MET B HA     1 
ATOM   7528  H HB2    . MET B 1 18  ? 5.752   19.092  -40.317 1.00 41.56  ? 18  MET B HB2    1 
ATOM   7529  H HB3    . MET B 1 18  ? 5.721   20.627  -39.948 1.00 41.56  ? 18  MET B HB3    1 
ATOM   7530  H HG2    . MET B 1 18  ? 5.213   18.552  -38.124 1.00 39.21  ? 18  MET B HG2    1 
ATOM   7531  H HG3    . MET B 1 18  ? 6.544   19.417  -38.174 1.00 39.21  ? 18  MET B HG3    1 
ATOM   7532  H HE1    . MET B 1 18  ? 5.506   22.795  -36.919 1.00 31.83  ? 18  MET B HE1    1 
ATOM   7533  H HE2    . MET B 1 18  ? 6.727   21.921  -37.439 1.00 31.83  ? 18  MET B HE2    1 
ATOM   7534  H HE3    . MET B 1 18  ? 5.582   22.366  -38.447 1.00 31.83  ? 18  MET B HE3    1 
ATOM   7535  N N      . ILE B 1 19  ? 2.574   20.299  -42.220 1.00 24.07  ? 19  ILE B N      1 
ATOM   7536  C CA     . ILE B 1 19  ? 2.409   20.650  -43.627 1.00 24.64  ? 19  ILE B CA     1 
ATOM   7537  C C      . ILE B 1 19  ? 2.596   22.149  -43.870 1.00 26.75  ? 19  ILE B C      1 
ATOM   7538  O O      . ILE B 1 19  ? 2.267   22.968  -43.013 1.00 26.00  ? 19  ILE B O      1 
ATOM   7539  C CB     . ILE B 1 19  ? 1.036   20.210  -44.126 1.00 29.95  ? 19  ILE B CB     1 
ATOM   7540  C CG1    . ILE B 1 19  ? -0.074  20.825  -43.268 1.00 27.74  ? 19  ILE B CG1    1 
ATOM   7541  C CG2    . ILE B 1 19  ? 0.949   18.682  -44.099 1.00 34.29  ? 19  ILE B CG2    1 
ATOM   7542  C CD1    . ILE B 1 19  ? -1.456  20.615  -43.824 1.00 27.38  ? 19  ILE B CD1    1 
ATOM   7543  H H      . ILE B 1 19  ? 1.842   20.135  -41.802 1.00 28.88  ? 19  ILE B H      1 
ATOM   7544  H HA     . ILE B 1 19  ? 3.077   20.167  -44.136 1.00 29.57  ? 19  ILE B HA     1 
ATOM   7545  H HB     . ILE B 1 19  ? 0.926   20.512  -45.041 1.00 35.93  ? 19  ILE B HB     1 
ATOM   7546  H HG12   . ILE B 1 19  ? -0.052  20.422  -42.386 1.00 33.28  ? 19  ILE B HG12   1 
ATOM   7547  H HG13   . ILE B 1 19  ? 0.067   21.781  -43.196 1.00 33.28  ? 19  ILE B HG13   1 
ATOM   7548  H HG21   . ILE B 1 19  ? 0.116   18.405  -44.512 1.00 41.14  ? 19  ILE B HG21   1 
ATOM   7549  H HG22   . ILE B 1 19  ? 1.700   18.315  -44.591 1.00 41.14  ? 19  ILE B HG22   1 
ATOM   7550  H HG23   . ILE B 1 19  ? 0.979   18.380  -43.178 1.00 41.14  ? 19  ILE B HG23   1 
ATOM   7551  H HD11   . ILE B 1 19  ? -2.093  21.102  -43.278 1.00 32.85  ? 19  ILE B HD11   1 
ATOM   7552  H HD12   . ILE B 1 19  ? -1.482  20.945  -44.736 1.00 32.85  ? 19  ILE B HD12   1 
ATOM   7553  H HD13   . ILE B 1 19  ? -1.663  19.668  -43.808 1.00 32.85  ? 19  ILE B HD13   1 
ATOM   7554  N N      . PRO B 1 20  ? 3.132   22.513  -45.049 1.00 26.53  ? 20  PRO B N      1 
ATOM   7555  C CA     . PRO B 1 20  ? 3.420   23.915  -45.344 1.00 24.82  ? 20  PRO B CA     1 
ATOM   7556  C C      . PRO B 1 20  ? 2.159   24.714  -45.661 1.00 23.18  ? 20  PRO B C      1 
ATOM   7557  O O      . PRO B 1 20  ? 1.088   24.138  -45.841 1.00 21.30  ? 20  PRO B O      1 
ATOM   7558  C CB     . PRO B 1 20  ? 4.336   23.829  -46.558 1.00 28.60  ? 20  PRO B CB     1 
ATOM   7559  C CG     . PRO B 1 20  ? 3.889   22.594  -47.256 1.00 28.89  ? 20  PRO B CG     1 
ATOM   7560  C CD     . PRO B 1 20  ? 3.488   21.633  -46.177 1.00 30.02  ? 20  PRO B CD     1 
ATOM   7561  H HA     . PRO B 1 20  ? 3.894   24.330  -44.606 1.00 29.78  ? 20  PRO B HA     1 
ATOM   7562  H HB2    . PRO B 1 20  ? 4.213   24.609  -47.121 1.00 34.32  ? 20  PRO B HB2    1 
ATOM   7563  H HB3    . PRO B 1 20  ? 5.259   23.750  -46.271 1.00 34.32  ? 20  PRO B HB3    1 
ATOM   7564  H HG2    . PRO B 1 20  ? 3.132   22.800  -47.827 1.00 34.67  ? 20  PRO B HG2    1 
ATOM   7565  H HG3    . PRO B 1 20  ? 4.622   22.233  -47.778 1.00 34.67  ? 20  PRO B HG3    1 
ATOM   7566  H HD2    . PRO B 1 20  ? 2.718   21.115  -46.455 1.00 36.02  ? 20  PRO B HD2    1 
ATOM   7567  H HD3    . PRO B 1 20  ? 4.235   21.062  -45.939 1.00 36.02  ? 20  PRO B HD3    1 
ATOM   7568  N N      . ARG B 1 21  ? 2.310   26.030  -45.742 1.00 23.39  ? 21  ARG B N      1 
ATOM   7569  C CA     . ARG B 1 21  ? 1.182   26.942  -45.890 1.00 24.38  ? 21  ARG B CA     1 
ATOM   7570  C C      . ARG B 1 21  ? 0.342   26.629  -47.120 1.00 23.63  ? 21  ARG B C      1 
ATOM   7571  O O      . ARG B 1 21  ? -0.886  26.614  -47.052 1.00 22.94  ? 21  ARG B O      1 
ATOM   7572  C CB     . ARG B 1 21  ? 1.696   28.380  -45.958 1.00 27.56  ? 21  ARG B CB     1 
ATOM   7573  C CG     . ARG B 1 21  ? 0.664   29.402  -46.386 1.00 29.21  ? 21  ARG B CG     1 
ATOM   7574  C CD     . ARG B 1 21  ? 1.309   30.762  -46.531 1.00 35.74  ? 21  ARG B CD     1 
ATOM   7575  N NE     . ARG B 1 21  ? 1.111   31.544  -45.323 1.00 45.15  ? 21  ARG B NE     1 
ATOM   7576  C CZ     . ARG B 1 21  ? 0.145   32.439  -45.161 1.00 47.17  ? 21  ARG B CZ     1 
ATOM   7577  N NH1    . ARG B 1 21  ? -0.712  32.701  -46.149 1.00 43.12  ? 21  ARG B NH1    1 
ATOM   7578  N NH2    . ARG B 1 21  ? 0.052   33.082  -44.007 1.00 46.04  ? 21  ARG B NH2    1 
ATOM   7579  H H      . ARG B 1 21  ? 3.072   26.428  -45.713 1.00 28.07  ? 21  ARG B H      1 
ATOM   7580  H HA     . ARG B 1 21  ? 0.610   26.865  -45.110 1.00 29.26  ? 21  ARG B HA     1 
ATOM   7581  H HB2    . ARG B 1 21  ? 2.016   28.636  -45.079 1.00 33.07  ? 21  ARG B HB2    1 
ATOM   7582  H HB3    . ARG B 1 21  ? 2.427   28.415  -46.595 1.00 33.07  ? 21  ARG B HB3    1 
ATOM   7583  H HG2    . ARG B 1 21  ? 0.288   29.164  -47.247 1.00 35.05  ? 21  ARG B HG2    1 
ATOM   7584  H HG3    . ARG B 1 21  ? -0.033  29.461  -45.714 1.00 35.05  ? 21  ARG B HG3    1 
ATOM   7585  H HD2    . ARG B 1 21  ? 2.264   30.649  -46.660 1.00 42.89  ? 21  ARG B HD2    1 
ATOM   7586  H HD3    . ARG B 1 21  ? 0.927   31.227  -47.290 1.00 42.89  ? 21  ARG B HD3    1 
ATOM   7587  H HE     . ARG B 1 21  ? 1.656   31.419  -44.670 1.00 54.19  ? 21  ARG B HE     1 
ATOM   7588  H HH11   . ARG B 1 21  ? -0.659  32.284  -46.898 1.00 51.74  ? 21  ARG B HH11   1 
ATOM   7589  H HH12   . ARG B 1 21  ? -1.331  33.287  -46.031 1.00 51.74  ? 21  ARG B HH12   1 
ATOM   7590  H HH21   . ARG B 1 21  ? 0.611   32.915  -43.375 1.00 55.25  ? 21  ARG B HH21   1 
ATOM   7591  H HH22   . ARG B 1 21  ? -0.563  33.672  -43.892 1.00 55.25  ? 21  ARG B HH22   1 
ATOM   7592  N N      . GLU B 1 22  ? 1.008   26.380  -48.242 1.00 25.63  ? 22  GLU B N      1 
ATOM   7593  C CA     . GLU B 1 22  ? 0.316   26.095  -49.492 1.00 27.82  ? 22  GLU B CA     1 
ATOM   7594  C C      . GLU B 1 22  ? -0.593  24.881  -49.332 1.00 25.73  ? 22  GLU B C      1 
ATOM   7595  O O      . GLU B 1 22  ? -1.711  24.843  -49.849 1.00 22.31  ? 22  GLU B O      1 
ATOM   7596  C CB     . GLU B 1 22  ? 1.326   25.863  -50.623 1.00 34.68  ? 22  GLU B CB     1 
ATOM   7597  C CG     . GLU B 1 22  ? 0.693   25.694  -51.994 1.00 60.89  ? 22  GLU B CG     1 
ATOM   7598  C CD     . GLU B 1 22  ? 1.715   25.421  -53.086 1.00 76.91  ? 22  GLU B CD     1 
ATOM   7599  O OE1    . GLU B 1 22  ? 2.906   25.746  -52.889 1.00 78.39  ? 22  GLU B OE1    1 
ATOM   7600  O OE2    . GLU B 1 22  ? 1.324   24.876  -54.141 1.00 81.48  ? 22  GLU B OE2    1 
ATOM   7601  H H      . GLU B 1 22  ? 1.866   26.370  -48.306 1.00 30.75  ? 22  GLU B H      1 
ATOM   7602  H HA     . GLU B 1 22  ? -0.236  26.856  -49.731 1.00 33.39  ? 22  GLU B HA     1 
ATOM   7603  H HB2    . GLU B 1 22  ? 1.925   26.625  -50.665 1.00 41.62  ? 22  GLU B HB2    1 
ATOM   7604  H HB3    . GLU B 1 22  ? 1.832   25.058  -50.429 1.00 41.62  ? 22  GLU B HB3    1 
ATOM   7605  H HG2    . GLU B 1 22  ? 0.076   24.946  -51.970 1.00 73.06  ? 22  GLU B HG2    1 
ATOM   7606  H HG3    . GLU B 1 22  ? 0.218   26.508  -52.225 1.00 73.06  ? 22  GLU B HG3    1 
ATOM   7607  N N      . GLU B 1 23  ? -0.113  23.891  -48.591 1.00 22.78  ? 23  GLU B N      1 
ATOM   7608  C CA     . GLU B 1 23  ? -0.893  22.685  -48.349 1.00 23.86  ? 23  GLU B CA     1 
ATOM   7609  C C      . GLU B 1 23  ? -2.030  22.949  -47.355 1.00 22.79  ? 23  GLU B C      1 
ATOM   7610  O O      . GLU B 1 23  ? -3.127  22.419  -47.520 1.00 19.39  ? 23  GLU B O      1 
ATOM   7611  C CB     . GLU B 1 23  ? 0.017   21.556  -47.851 1.00 26.71  ? 23  GLU B CB     1 
ATOM   7612  C CG     . GLU B 1 23  ? -0.679  20.198  -47.781 1.00 43.55  ? 23  GLU B CG     1 
ATOM   7613  C CD     . GLU B 1 23  ? 0.286   19.036  -47.558 1.00 70.58  ? 23  GLU B CD     1 
ATOM   7614  O OE1    . GLU B 1 23  ? 1.516   19.244  -47.637 1.00 65.79  ? 23  GLU B OE1    1 
ATOM   7615  O OE2    . GLU B 1 23  ? -0.192  17.908  -47.305 1.00 62.04  ? 23  GLU B OE2    1 
ATOM   7616  H H      . GLU B 1 23  ? 0.661   23.892  -48.217 1.00 27.33  ? 23  GLU B H      1 
ATOM   7617  H HA     . GLU B 1 23  ? -1.291  22.396  -49.185 1.00 28.63  ? 23  GLU B HA     1 
ATOM   7618  H HB2    . GLU B 1 23  ? 0.770   21.477  -48.457 1.00 32.05  ? 23  GLU B HB2    1 
ATOM   7619  H HB3    . GLU B 1 23  ? 0.332   21.776  -46.960 1.00 32.05  ? 23  GLU B HB3    1 
ATOM   7620  H HG2    . GLU B 1 23  ? -1.311  20.206  -47.045 1.00 52.26  ? 23  GLU B HG2    1 
ATOM   7621  H HG3    . GLU B 1 23  ? -1.147  20.041  -48.616 1.00 52.26  ? 23  GLU B HG3    1 
ATOM   7622  N N      . ARG B 1 24  ? -1.788  23.783  -46.344 1.00 20.16  ? 24  ARG B N      1 
ATOM   7623  C CA     . ARG B 1 24  ? -2.859  24.150  -45.410 1.00 19.10  ? 24  ARG B CA     1 
ATOM   7624  C C      . ARG B 1 24  ? -3.995  24.869  -46.132 1.00 19.25  ? 24  ARG B C      1 
ATOM   7625  O O      . ARG B 1 24  ? -5.168  24.596  -45.888 1.00 18.56  ? 24  ARG B O      1 
ATOM   7626  C CB     . ARG B 1 24  ? -2.339  25.041  -44.279 1.00 18.06  ? 24  ARG B CB     1 
ATOM   7627  C CG     . ARG B 1 24  ? -1.390  24.350  -43.312 1.00 21.51  ? 24  ARG B CG     1 
ATOM   7628  C CD     . ARG B 1 24  ? -1.226  25.151  -42.013 1.00 19.33  ? 24  ARG B CD     1 
ATOM   7629  N NE     . ARG B 1 24  ? -0.666  26.484  -42.218 1.00 19.26  ? 24  ARG B NE     1 
ATOM   7630  C CZ     . ARG B 1 24  ? 0.634   26.761  -42.306 1.00 25.49  ? 24  ARG B CZ     1 
ATOM   7631  N NH1    . ARG B 1 24  ? 1.541   25.793  -42.226 1.00 24.58  ? 24  ARG B NH1    1 
ATOM   7632  N NH2    . ARG B 1 24  ? 1.031   28.016  -42.492 1.00 23.21  ? 24  ARG B NH2    1 
ATOM   7633  H H      . ARG B 1 24  ? -1.027  24.146  -46.177 1.00 24.20  ? 24  ARG B H      1 
ATOM   7634  H HA     . ARG B 1 24  ? -3.221  23.342  -45.012 1.00 22.92  ? 24  ARG B HA     1 
ATOM   7635  H HB2    . ARG B 1 24  ? -1.865  25.792  -44.669 1.00 21.68  ? 24  ARG B HB2    1 
ATOM   7636  H HB3    . ARG B 1 24  ? -3.096  25.364  -43.766 1.00 21.68  ? 24  ARG B HB3    1 
ATOM   7637  H HG2    . ARG B 1 24  ? -1.744  23.475  -43.087 1.00 25.81  ? 24  ARG B HG2    1 
ATOM   7638  H HG3    . ARG B 1 24  ? -0.518  24.263  -43.727 1.00 25.81  ? 24  ARG B HG3    1 
ATOM   7639  H HD2    . ARG B 1 24  ? -2.098  25.258  -41.602 1.00 23.20  ? 24  ARG B HD2    1 
ATOM   7640  H HD3    . ARG B 1 24  ? -0.639  24.665  -41.414 1.00 23.20  ? 24  ARG B HD3    1 
ATOM   7641  H HE     . ARG B 1 24  ? -1.218  27.140  -42.287 1.00 23.11  ? 24  ARG B HE     1 
ATOM   7642  H HH11   . ARG B 1 24  ? 1.296   24.978  -42.107 1.00 29.50  ? 24  ARG B HH11   1 
ATOM   7643  H HH12   . ARG B 1 24  ? 2.377   25.984  -42.287 1.00 29.50  ? 24  ARG B HH12   1 
ATOM   7644  H HH21   . ARG B 1 24  ? 0.450   28.647  -42.548 1.00 27.85  ? 24  ARG B HH21   1 
ATOM   7645  H HH22   . ARG B 1 24  ? 1.869   28.197  -42.554 1.00 27.85  ? 24  ARG B HH22   1 
ATOM   7646  N N      . ILE B 1 25  ? -3.645  25.791  -47.021 1.00 18.19  ? 25  ILE B N      1 
ATOM   7647  C CA     . ILE B 1 25  ? -4.658  26.494  -47.804 1.00 22.05  ? 25  ILE B CA     1 
ATOM   7648  C C      . ILE B 1 25  ? -5.476  25.496  -48.636 1.00 20.26  ? 25  ILE B C      1 
ATOM   7649  O O      . ILE B 1 25  ? -6.710  25.565  -48.687 1.00 17.61  ? 25  ILE B O      1 
ATOM   7650  C CB     . ILE B 1 25  ? -4.005  27.566  -48.696 1.00 20.08  ? 25  ILE B CB     1 
ATOM   7651  C CG1    . ILE B 1 25  ? -3.396  28.665  -47.803 1.00 19.02  ? 25  ILE B CG1    1 
ATOM   7652  C CG2    . ILE B 1 25  ? -5.029  28.175  -49.678 1.00 21.20  ? 25  ILE B CG2    1 
ATOM   7653  C CD1    . ILE B 1 25  ? -2.569  29.705  -48.544 1.00 24.99  ? 25  ILE B CD1    1 
ATOM   7654  H H      . ILE B 1 25  ? -2.836  26.028  -47.190 1.00 21.82  ? 25  ILE B H      1 
ATOM   7655  H HA     . ILE B 1 25  ? -5.267  26.944  -47.197 1.00 26.46  ? 25  ILE B HA     1 
ATOM   7656  H HB     . ILE B 1 25  ? -3.293  27.152  -49.208 1.00 24.09  ? 25  ILE B HB     1 
ATOM   7657  H HG12   . ILE B 1 25  ? -4.118  29.132  -47.354 1.00 22.82  ? 25  ILE B HG12   1 
ATOM   7658  H HG13   . ILE B 1 25  ? -2.820  28.248  -47.144 1.00 22.82  ? 25  ILE B HG13   1 
ATOM   7659  H HG21   . ILE B 1 25  ? -4.639  28.954  -50.104 1.00 25.44  ? 25  ILE B HG21   1 
ATOM   7660  H HG22   . ILE B 1 25  ? -5.256  27.515  -50.352 1.00 25.44  ? 25  ILE B HG22   1 
ATOM   7661  H HG23   . ILE B 1 25  ? -5.823  28.433  -49.185 1.00 25.44  ? 25  ILE B HG23   1 
ATOM   7662  H HD11   . ILE B 1 25  ? -2.080  30.238  -47.897 1.00 29.99  ? 25  ILE B HD11   1 
ATOM   7663  H HD12   . ILE B 1 25  ? -1.948  29.251  -49.135 1.00 29.99  ? 25  ILE B HD12   1 
ATOM   7664  H HD13   . ILE B 1 25  ? -3.162  30.273  -49.060 1.00 29.99  ? 25  ILE B HD13   1 
ATOM   7665  N N      . LYS B 1 26  ? -4.799  24.550  -49.273 1.00 18.47  ? 26  LYS B N      1 
ATOM   7666  C CA     . LYS B 1 26  ? -5.498  23.527  -50.044 1.00 19.98  ? 26  LYS B CA     1 
ATOM   7667  C C      . LYS B 1 26  ? -6.469  22.725  -49.164 1.00 21.45  ? 26  LYS B C      1 
ATOM   7668  O O      . LYS B 1 26  ? -7.624  22.506  -49.545 1.00 19.12  ? 26  LYS B O      1 
ATOM   7669  C CB     . LYS B 1 26  ? -4.487  22.599  -50.726 1.00 24.45  ? 26  LYS B CB     1 
ATOM   7670  C CG     . LYS B 1 26  ? -5.109  21.568  -51.643 1.00 36.88  ? 26  LYS B CG     1 
ATOM   7671  C CD     . LYS B 1 26  ? -4.042  20.817  -52.446 1.00 47.14  ? 26  LYS B CD     1 
ATOM   7672  C CE     . LYS B 1 26  ? -4.620  19.592  -53.154 1.00 58.24  ? 26  LYS B CE     1 
ATOM   7673  N NZ     . LYS B 1 26  ? -4.299  19.557  -54.612 1.00 64.36  ? 26  LYS B NZ     1 
ATOM   7674  H H      . LYS B 1 26  ? -3.942  24.477  -49.276 1.00 22.16  ? 26  LYS B H      1 
ATOM   7675  H HA     . LYS B 1 26  ? -6.018  23.961  -50.739 1.00 23.97  ? 26  LYS B HA     1 
ATOM   7676  H HB2    . LYS B 1 26  ? -3.879  23.138  -51.257 1.00 29.34  ? 26  LYS B HB2    1 
ATOM   7677  H HB3    . LYS B 1 26  ? -3.990  22.124  -50.042 1.00 29.34  ? 26  LYS B HB3    1 
ATOM   7678  H HG2    . LYS B 1 26  ? -5.609  20.929  -51.117 1.00 44.25  ? 26  LYS B HG2    1 
ATOM   7679  H HG3    . LYS B 1 26  ? -5.698  22.016  -52.270 1.00 44.25  ? 26  LYS B HG3    1 
ATOM   7680  H HD2    . LYS B 1 26  ? -3.673  21.410  -53.119 1.00 56.57  ? 26  LYS B HD2    1 
ATOM   7681  H HD3    . LYS B 1 26  ? -3.342  20.517  -51.845 1.00 56.57  ? 26  LYS B HD3    1 
ATOM   7682  H HE2    . LYS B 1 26  ? -4.253  18.791  -52.748 1.00 69.89  ? 26  LYS B HE2    1 
ATOM   7683  H HE3    . LYS B 1 26  ? -5.585  19.599  -53.060 1.00 69.89  ? 26  LYS B HE3    1 
ATOM   7684  H HZ1    . LYS B 1 26  ? -4.653  18.830  -54.984 1.00 77.23  ? 26  LYS B HZ1    1 
ATOM   7685  H HZ2    . LYS B 1 26  ? -4.631  20.279  -55.014 1.00 77.23  ? 26  LYS B HZ2    1 
ATOM   7686  H HZ3    . LYS B 1 26  ? -3.417  19.541  -54.729 1.00 77.23  ? 26  LYS B HZ3    1 
ATOM   7687  N N      . ARG B 1 27  ? -6.020  22.313  -47.982 1.00 18.99  ? 27  ARG B N      1 
ATOM   7688  C CA     . ARG B 1 27  ? -6.876  21.543  -47.081 1.00 20.79  ? 27  ARG B CA     1 
ATOM   7689  C C      . ARG B 1 27  ? -8.026  22.396  -46.537 1.00 16.44  ? 27  ARG B C      1 
ATOM   7690  O O      . ARG B 1 27  ? -9.133  21.901  -46.369 1.00 16.70  ? 27  ARG B O      1 
ATOM   7691  C CB     . ARG B 1 27  ? -6.071  20.965  -45.914 1.00 20.38  ? 27  ARG B CB     1 
ATOM   7692  C CG     . ARG B 1 27  ? -4.951  19.994  -46.312 1.00 24.26  ? 27  ARG B CG     1 
ATOM   7693  C CD     . ARG B 1 27  ? -5.468  18.721  -46.973 1.00 33.72  ? 27  ARG B CD     1 
ATOM   7694  N NE     . ARG B 1 27  ? -4.473  18.163  -47.895 1.00 48.59  ? 27  ARG B NE     1 
ATOM   7695  C CZ     . ARG B 1 27  ? -4.531  18.236  -49.224 1.00 49.49  ? 27  ARG B CZ     1 
ATOM   7696  N NH1    . ARG B 1 27  ? -5.545  18.835  -49.831 1.00 44.89  ? 27  ARG B NH1    1 
ATOM   7697  N NH2    . ARG B 1 27  ? -3.571  17.692  -49.958 1.00 67.63  ? 27  ARG B NH2    1 
ATOM   7698  H H      . ARG B 1 27  ? -5.230  22.464  -47.679 1.00 22.79  ? 27  ARG B H      1 
ATOM   7699  H HA     . ARG B 1 27  ? -7.268  20.807  -47.575 1.00 24.94  ? 27  ARG B HA     1 
ATOM   7700  H HB2    . ARG B 1 27  ? -5.663  21.699  -45.428 1.00 24.46  ? 27  ARG B HB2    1 
ATOM   7701  H HB3    . ARG B 1 27  ? -6.678  20.486  -45.328 1.00 24.46  ? 27  ARG B HB3    1 
ATOM   7702  H HG2    . ARG B 1 27  ? -4.362  20.431  -46.943 1.00 29.12  ? 27  ARG B HG2    1 
ATOM   7703  H HG3    . ARG B 1 27  ? -4.456  19.740  -45.517 1.00 29.12  ? 27  ARG B HG3    1 
ATOM   7704  H HD2    . ARG B 1 27  ? -5.636  18.059  -46.285 1.00 40.46  ? 27  ARG B HD2    1 
ATOM   7705  H HD3    . ARG B 1 27  ? -6.286  18.905  -47.455 1.00 40.46  ? 27  ARG B HD3    1 
ATOM   7706  H HE     . ARG B 1 27  ? -3.798  17.756  -47.550 1.00 58.31  ? 27  ARG B HE     1 
ATOM   7707  H HH11   . ARG B 1 27  ? -6.175  19.194  -49.372 1.00 53.86  ? 27  ARG B HH11   1 
ATOM   7708  H HH12   . ARG B 1 27  ? -5.567  18.872  -50.690 1.00 53.86  ? 27  ARG B HH12   1 
ATOM   7709  H HH21   . ARG B 1 27  ? -2.909  17.297  -49.576 1.00 81.16  ? 27  ARG B HH21   1 
ATOM   7710  H HH22   . ARG B 1 27  ? -3.609  17.736  -50.816 1.00 81.16  ? 27  ARG B HH22   1 
ATOM   7711  N N      . MET B 1 28  ? -7.768  23.675  -46.271 1.00 16.69  ? 28  MET B N      1 
ATOM   7712  C CA     . MET B 1 28  ? -8.824  24.558  -45.766 1.00 15.60  ? 28  MET B CA     1 
ATOM   7713  C C      . MET B 1 28  ? -9.919  24.722  -46.817 1.00 17.89  ? 28  MET B C      1 
ATOM   7714  O O      . MET B 1 28  ? -11.112 24.680  -46.501 1.00 17.91  ? 28  MET B O      1 
ATOM   7715  C CB     . MET B 1 28  ? -8.267  25.922  -45.373 1.00 19.43  ? 28  MET B CB     1 
ATOM   7716  C CG     . MET B 1 28  ? -9.249  26.794  -44.597 1.00 16.37  ? 28  MET B CG     1 
ATOM   7717  S SD     . MET B 1 28  ? -9.483  26.263  -42.883 1.00 22.83  ? 28  MET B SD     1 
ATOM   7718  C CE     . MET B 1 28  ? -11.022 25.357  -42.900 1.00 19.03  ? 28  MET B CE     1 
ATOM   7719  H H      . MET B 1 28  ? -7.002  24.054  -46.372 1.00 20.02  ? 28  MET B H      1 
ATOM   7720  H HA     . MET B 1 28  ? -9.211  24.157  -44.972 1.00 18.72  ? 28  MET B HA     1 
ATOM   7721  H HB2    . MET B 1 28  ? -7.484  25.790  -44.816 1.00 23.32  ? 28  MET B HB2    1 
ATOM   7722  H HB3    . MET B 1 28  ? -8.019  26.401  -46.179 1.00 23.32  ? 28  MET B HB3    1 
ATOM   7723  H HG2    . MET B 1 28  ? -8.915  27.705  -44.583 1.00 19.65  ? 28  MET B HG2    1 
ATOM   7724  H HG3    . MET B 1 28  ? -10.111 26.767  -45.038 1.00 19.65  ? 28  MET B HG3    1 
ATOM   7725  H HE1    . MET B 1 28  ? -11.756 25.989  -42.885 1.00 22.83  ? 28  MET B HE1    1 
ATOM   7726  H HE2    . MET B 1 28  ? -11.064 24.817  -43.705 1.00 22.83  ? 28  MET B HE2    1 
ATOM   7727  H HE3    . MET B 1 28  ? -11.061 24.789  -42.115 1.00 22.83  ? 28  MET B HE3    1 
ATOM   7728  N N      . ARG B 1 29  ? -9.514  24.917  -48.067 1.00 17.37  ? 29  ARG B N      1 
ATOM   7729  C CA     . ARG B 1 29  ? -10.482 25.060  -49.154 1.00 20.60  ? 29  ARG B CA     1 
ATOM   7730  C C      . ARG B 1 29  ? -11.276 23.764  -49.360 1.00 19.83  ? 29  ARG B C      1 
ATOM   7731  O O      . ARG B 1 29  ? -12.487 23.798  -49.596 1.00 22.31  ? 29  ARG B O      1 
ATOM   7732  C CB     . ARG B 1 29  ? -9.780  25.471  -50.454 1.00 20.62  ? 29  ARG B CB     1 
ATOM   7733  C CG     . ARG B 1 29  ? -10.753 25.743  -51.585 1.00 20.78  ? 29  ARG B CG     1 
ATOM   7734  C CD     . ARG B 1 29  ? -10.094 26.434  -52.766 1.00 29.53  ? 29  ARG B CD     1 
ATOM   7735  N NE     . ARG B 1 29  ? -11.132 27.046  -53.588 1.00 34.59  ? 29  ARG B NE     1 
ATOM   7736  C CZ     . ARG B 1 29  ? -11.913 26.373  -54.422 1.00 36.99  ? 29  ARG B CZ     1 
ATOM   7737  N NH1    . ARG B 1 29  ? -11.754 25.060  -54.573 1.00 32.05  ? 29  ARG B NH1    1 
ATOM   7738  N NH2    . ARG B 1 29  ? -12.853 27.018  -55.108 1.00 39.74  ? 29  ARG B NH2    1 
ATOM   7739  H H      . ARG B 1 29  ? -8.692  24.970  -48.313 1.00 20.85  ? 29  ARG B H      1 
ATOM   7740  H HA     . ARG B 1 29  ? -11.112 25.761  -48.922 1.00 24.72  ? 29  ARG B HA     1 
ATOM   7741  H HB2    . ARG B 1 29  ? -9.270  26.281  -50.295 1.00 24.74  ? 29  ARG B HB2    1 
ATOM   7742  H HB3    . ARG B 1 29  ? -9.188  24.755  -50.733 1.00 24.74  ? 29  ARG B HB3    1 
ATOM   7743  H HG2    . ARG B 1 29  ? -11.120 24.901  -51.897 1.00 24.94  ? 29  ARG B HG2    1 
ATOM   7744  H HG3    . ARG B 1 29  ? -11.464 26.316  -51.260 1.00 24.94  ? 29  ARG B HG3    1 
ATOM   7745  H HD2    . ARG B 1 29  ? -9.499  27.131  -52.448 1.00 35.44  ? 29  ARG B HD2    1 
ATOM   7746  H HD3    . ARG B 1 29  ? -9.608  25.786  -53.300 1.00 35.44  ? 29  ARG B HD3    1 
ATOM   7747  H HE     . ARG B 1 29  ? -11.205 27.903  -53.572 1.00 41.50  ? 29  ARG B HE     1 
ATOM   7748  H HH11   . ARG B 1 29  ? -11.153 24.643  -54.124 1.00 38.46  ? 29  ARG B HH11   1 
ATOM   7749  H HH12   . ARG B 1 29  ? -12.259 24.627  -55.118 1.00 38.46  ? 29  ARG B HH12   1 
ATOM   7750  H HH21   . ARG B 1 29  ? -12.948 27.868  -55.013 1.00 47.69  ? 29  ARG B HH21   1 
ATOM   7751  H HH22   . ARG B 1 29  ? -13.353 26.589  -55.660 1.00 47.69  ? 29  ARG B HH22   1 
ATOM   7752  N N      . GLU B 1 30  ? -10.604 22.622  -49.249 1.00 21.00  ? 30  GLU B N      1 
ATOM   7753  C CA     . GLU B 1 30  ? -11.283 21.334  -49.362 1.00 20.03  ? 30  GLU B CA     1 
ATOM   7754  C C      . GLU B 1 30  ? -12.305 21.177  -48.247 1.00 21.27  ? 30  GLU B C      1 
ATOM   7755  O O      . GLU B 1 30  ? -13.331 20.517  -48.429 1.00 23.87  ? 30  GLU B O      1 
ATOM   7756  C CB     . GLU B 1 30  ? -10.278 20.174  -49.327 1.00 26.69  ? 30  GLU B CB     1 
ATOM   7757  C CG     . GLU B 1 30  ? -9.515  19.973  -50.642 1.00 34.35  ? 30  GLU B CG     1 
ATOM   7758  C CD     . GLU B 1 30  ? -8.347  18.990  -50.525 1.00 46.79  ? 30  GLU B CD     1 
ATOM   7759  O OE1    . GLU B 1 30  ? -8.077  18.488  -49.408 1.00 37.93  ? 30  GLU B OE1    1 
ATOM   7760  O OE2    . GLU B 1 30  ? -7.686  18.729  -51.554 1.00 39.56  ? 30  GLU B OE2    1 
ATOM   7761  H H      . GLU B 1 30  ? -9.757  22.565  -49.109 1.00 25.20  ? 30  GLU B H      1 
ATOM   7762  H HA     . GLU B 1 30  ? -11.754 21.298  -50.209 1.00 24.04  ? 30  GLU B HA     1 
ATOM   7763  H HB2    . GLU B 1 30  ? -9.627  20.349  -48.629 1.00 32.03  ? 30  GLU B HB2    1 
ATOM   7764  H HB3    . GLU B 1 30  ? -10.756 19.352  -49.133 1.00 32.03  ? 30  GLU B HB3    1 
ATOM   7765  H HG2    . GLU B 1 30  ? -10.127 19.630  -51.312 1.00 41.23  ? 30  GLU B HG2    1 
ATOM   7766  H HG3    . GLU B 1 30  ? -9.157  20.826  -50.928 1.00 41.23  ? 30  GLU B HG3    1 
ATOM   7767  N N      . ALA B 1 31  ? -12.031 21.806  -47.100 1.00 19.77  ? 31  ALA B N      1 
ATOM   7768  C CA     . ALA B 1 31  ? -12.952 21.795  -45.963 1.00 18.04  ? 31  ALA B CA     1 
ATOM   7769  C C      . ALA B 1 31  ? -13.974 22.940  -46.047 1.00 20.60  ? 31  ALA B C      1 
ATOM   7770  O O      . ALA B 1 31  ? -14.653 23.252  -45.069 1.00 21.99  ? 31  ALA B O      1 
ATOM   7771  C CB     . ALA B 1 31  ? -12.169 21.876  -44.646 1.00 20.25  ? 31  ALA B CB     1 
ATOM   7772  H H      . ALA B 1 31  ? -11.309 22.250  -46.955 1.00 23.72  ? 31  ALA B H      1 
ATOM   7773  H HA     . ALA B 1 31  ? -13.443 20.959  -45.962 1.00 21.65  ? 31  ALA B HA     1 
ATOM   7774  H HB1    . ALA B 1 31  ? -12.794 21.856  -43.905 1.00 24.30  ? 31  ALA B HB1    1 
ATOM   7775  H HB2    . ALA B 1 31  ? -11.566 21.118  -44.591 1.00 24.30  ? 31  ALA B HB2    1 
ATOM   7776  H HB3    . ALA B 1 31  ? -11.663 22.703  -44.631 1.00 24.30  ? 31  ALA B HB3    1 
ATOM   7777  N N      . GLY B 1 32  ? -14.079 23.567  -47.213 1.00 21.02  ? 32  GLY B N      1 
ATOM   7778  C CA     . GLY B 1 32  ? -15.044 24.638  -47.422 1.00 19.44  ? 32  GLY B CA     1 
ATOM   7779  C C      . GLY B 1 32  ? -14.872 25.809  -46.467 1.00 20.56  ? 32  GLY B C      1 
ATOM   7780  O O      . GLY B 1 32  ? -15.845 26.476  -46.107 1.00 18.53  ? 32  GLY B O      1 
ATOM   7781  H H      . GLY B 1 32  ? -13.601 23.391  -47.905 1.00 25.23  ? 32  GLY B H      1 
ATOM   7782  H HA2    . GLY B 1 32  ? -14.959 24.971  -48.329 1.00 23.33  ? 32  GLY B HA2    1 
ATOM   7783  H HA3    . GLY B 1 32  ? -15.941 24.285  -47.311 1.00 23.33  ? 32  GLY B HA3    1 
ATOM   7784  N N      . TYR B 1 33  ? -13.621 26.048  -46.070 1.00 20.36  ? 33  TYR B N      1 
ATOM   7785  C CA     . TYR B 1 33  ? -13.263 27.096  -45.115 1.00 20.67  ? 33  TYR B CA     1 
ATOM   7786  C C      . TYR B 1 33  ? -14.058 26.956  -43.812 1.00 18.87  ? 33  TYR B C      1 
ATOM   7787  O O      . TYR B 1 33  ? -14.318 27.928  -43.106 1.00 19.58  ? 33  TYR B O      1 
ATOM   7788  C CB     . TYR B 1 33  ? -13.453 28.478  -45.759 1.00 21.33  ? 33  TYR B CB     1 
ATOM   7789  C CG     . TYR B 1 33  ? -12.589 28.647  -46.988 1.00 18.18  ? 33  TYR B CG     1 
ATOM   7790  C CD1    . TYR B 1 33  ? -11.220 28.862  -46.871 1.00 21.80  ? 33  TYR B CD1    1 
ATOM   7791  C CD2    . TYR B 1 33  ? -13.131 28.560  -48.265 1.00 22.64  ? 33  TYR B CD2    1 
ATOM   7792  C CE1    . TYR B 1 33  ? -10.418 28.994  -47.986 1.00 22.47  ? 33  TYR B CE1    1 
ATOM   7793  C CE2    . TYR B 1 33  ? -12.337 28.699  -49.389 1.00 22.72  ? 33  TYR B CE2    1 
ATOM   7794  C CZ     . TYR B 1 33  ? -10.984 28.913  -49.248 1.00 23.12  ? 33  TYR B CZ     1 
ATOM   7795  O OH     . TYR B 1 33  ? -10.183 29.051  -50.357 1.00 22.55  ? 33  TYR B OH     1 
ATOM   7796  H H      . TYR B 1 33  ? -12.942 25.601  -46.350 1.00 24.43  ? 33  TYR B H      1 
ATOM   7797  H HA     . TYR B 1 33  ? -12.324 27.004  -44.894 1.00 24.81  ? 33  TYR B HA     1 
ATOM   7798  H HB2    . TYR B 1 33  ? -14.380 28.585  -46.023 1.00 25.60  ? 33  TYR B HB2    1 
ATOM   7799  H HB3    . TYR B 1 33  ? -13.206 29.165  -45.120 1.00 25.60  ? 33  TYR B HB3    1 
ATOM   7800  H HD1    . TYR B 1 33  ? -10.837 28.914  -46.025 1.00 26.16  ? 33  TYR B HD1    1 
ATOM   7801  H HD2    . TYR B 1 33  ? -14.044 28.413  -48.365 1.00 27.17  ? 33  TYR B HD2    1 
ATOM   7802  H HE1    . TYR B 1 33  ? -9.505  29.143  -47.891 1.00 26.96  ? 33  TYR B HE1    1 
ATOM   7803  H HE2    . TYR B 1 33  ? -12.715 28.642  -50.237 1.00 27.26  ? 33  TYR B HE2    1 
ATOM   7804  H HH     . TYR B 1 33  ? -10.638 28.946  -51.055 1.00 27.05  ? 33  TYR B HH     1 
ATOM   7805  N N      . ASN B 1 34  ? -14.412 25.718  -43.488 1.00 19.32  ? 34  ASN B N      1 
ATOM   7806  C CA     . ASN B 1 34  ? -15.075 25.389  -42.232 1.00 18.64  ? 34  ASN B CA     1 
ATOM   7807  C C      . ASN B 1 34  ? -14.145 24.506  -41.384 1.00 21.27  ? 34  ASN B C      1 
ATOM   7808  O O      . ASN B 1 34  ? -13.862 23.380  -41.763 1.00 18.25  ? 34  ASN B O      1 
ATOM   7809  C CB     . ASN B 1 34  ? -16.398 24.680  -42.522 1.00 21.64  ? 34  ASN B CB     1 
ATOM   7810  C CG     . ASN B 1 34  ? -17.137 24.253  -41.266 1.00 21.40  ? 34  ASN B CG     1 
ATOM   7811  O OD1    . ASN B 1 34  ? -16.666 24.441  -40.142 1.00 20.70  ? 34  ASN B OD1    1 
ATOM   7812  N ND2    . ASN B 1 34  ? -18.318 23.698  -41.457 1.00 20.43  ? 34  ASN B ND2    1 
ATOM   7813  H H      . ASN B 1 34  ? -14.275 25.034  -43.990 1.00 23.19  ? 34  ASN B H      1 
ATOM   7814  H HA     . ASN B 1 34  ? -15.267 26.196  -41.731 1.00 22.37  ? 34  ASN B HA     1 
ATOM   7815  H HB2    . ASN B 1 34  ? -16.975 25.282  -43.018 1.00 25.97  ? 34  ASN B HB2    1 
ATOM   7816  H HB3    . ASN B 1 34  ? -16.220 23.885  -43.048 1.00 25.97  ? 34  ASN B HB3    1 
ATOM   7817  H HD21   . ASN B 1 34  ? -18.784 23.436  -40.783 1.00 24.51  ? 34  ASN B HD21   1 
ATOM   7818  H HD22   . ASN B 1 34  ? -18.622 23.598  -42.255 1.00 24.51  ? 34  ASN B HD22   1 
ATOM   7819  N N      . THR B 1 35  ? -13.653 25.009  -40.253 1.00 20.91  ? 35  THR B N      1 
ATOM   7820  C CA     . THR B 1 35  ? -12.659 24.241  -39.495 1.00 17.95  ? 35  THR B CA     1 
ATOM   7821  C C      . THR B 1 35  ? -13.225 22.936  -38.935 1.00 18.57  ? 35  THR B C      1 
ATOM   7822  O O      . THR B 1 35  ? -12.461 22.016  -38.630 1.00 18.02  ? 35  THR B O      1 
ATOM   7823  C CB     . THR B 1 35  ? -12.058 25.045  -38.319 1.00 18.22  ? 35  THR B CB     1 
ATOM   7824  O OG1    . THR B 1 35  ? -13.107 25.528  -37.477 1.00 20.20  ? 35  THR B OG1    1 
ATOM   7825  C CG2    . THR B 1 35  ? -11.198 26.203  -38.834 1.00 19.99  ? 35  THR B CG2    1 
ATOM   7826  H H      . THR B 1 35  ? -13.868 25.768  -39.910 1.00 25.09  ? 35  THR B H      1 
ATOM   7827  H HA     . THR B 1 35  ? -11.930 24.010  -40.092 1.00 21.54  ? 35  THR B HA     1 
ATOM   7828  H HB     . THR B 1 35  ? -11.486 24.459  -37.800 1.00 21.86  ? 35  THR B HB     1 
ATOM   7829  H HG1    . THR B 1 35  ? -12.783 25.965  -36.837 1.00 24.24  ? 35  THR B HG1    1 
ATOM   7830  H HG21   . THR B 1 35  ? -10.831 26.701  -38.087 1.00 23.98  ? 35  THR B HG21   1 
ATOM   7831  H HG22   . THR B 1 35  ? -10.468 25.860  -39.373 1.00 23.98  ? 35  THR B HG22   1 
ATOM   7832  H HG23   . THR B 1 35  ? -11.737 26.800  -39.376 1.00 23.98  ? 35  THR B HG23   1 
ATOM   7833  N N      . PHE B 1 36  ? -14.546 22.834  -38.795 1.00 19.61  ? 36  PHE B N      1 
ATOM   7834  C CA     . PHE B 1 36  ? -15.138 21.570  -38.356 1.00 19.94  ? 36  PHE B CA     1 
ATOM   7835  C C      . PHE B 1 36  ? -14.960 20.455  -39.388 1.00 21.08  ? 36  PHE B C      1 
ATOM   7836  O O      . PHE B 1 36  ? -15.096 19.283  -39.061 1.00 21.80  ? 36  PHE B O      1 
ATOM   7837  C CB     . PHE B 1 36  ? -16.625 21.726  -38.054 1.00 24.37  ? 36  PHE B CB     1 
ATOM   7838  C CG     . PHE B 1 36  ? -16.976 21.511  -36.613 1.00 23.27  ? 36  PHE B CG     1 
ATOM   7839  C CD1    . PHE B 1 36  ? -16.988 20.236  -36.073 1.00 26.12  ? 36  PHE B CD1    1 
ATOM   7840  C CD2    . PHE B 1 36  ? -17.313 22.583  -35.802 1.00 25.52  ? 36  PHE B CD2    1 
ATOM   7841  C CE1    . PHE B 1 36  ? -17.324 20.035  -34.737 1.00 25.84  ? 36  PHE B CE1    1 
ATOM   7842  C CE2    . PHE B 1 36  ? -17.642 22.390  -34.473 1.00 23.71  ? 36  PHE B CE2    1 
ATOM   7843  C CZ     . PHE B 1 36  ? -17.649 21.116  -33.942 1.00 27.86  ? 36  PHE B CZ     1 
ATOM   7844  H H      . PHE B 1 36  ? -15.110 23.466  -38.944 1.00 23.54  ? 36  PHE B H      1 
ATOM   7845  H HA     . PHE B 1 36  ? -14.699 21.288  -37.538 1.00 23.93  ? 36  PHE B HA     1 
ATOM   7846  H HB2    . PHE B 1 36  ? -16.903 22.623  -38.295 1.00 29.25  ? 36  PHE B HB2    1 
ATOM   7847  H HB3    . PHE B 1 36  ? -17.120 21.077  -38.579 1.00 29.25  ? 36  PHE B HB3    1 
ATOM   7848  H HD1    . PHE B 1 36  ? -16.769 19.507  -36.608 1.00 31.34  ? 36  PHE B HD1    1 
ATOM   7849  H HD2    . PHE B 1 36  ? -17.309 23.444  -36.154 1.00 30.62  ? 36  PHE B HD2    1 
ATOM   7850  H HE1    . PHE B 1 36  ? -17.326 19.176  -34.380 1.00 31.01  ? 36  PHE B HE1    1 
ATOM   7851  H HE2    . PHE B 1 36  ? -17.863 23.118  -33.938 1.00 28.46  ? 36  PHE B HE2    1 
ATOM   7852  H HZ     . PHE B 1 36  ? -17.872 20.986  -33.049 1.00 33.43  ? 36  PHE B HZ     1 
ATOM   7853  N N      . LEU B 1 37  ? -14.688 20.819  -40.639 1.00 20.11  ? 37  LEU B N      1 
ATOM   7854  C CA     . LEU B 1 37  ? -14.520 19.823  -41.688 1.00 19.76  ? 37  LEU B CA     1 
ATOM   7855  C C      . LEU B 1 37  ? -13.058 19.464  -41.916 1.00 20.86  ? 37  LEU B C      1 
ATOM   7856  O O      . LEU B 1 37  ? -12.760 18.638  -42.773 1.00 19.99  ? 37  LEU B O      1 
ATOM   7857  C CB     . LEU B 1 37  ? -15.142 20.313  -42.996 1.00 22.00  ? 37  LEU B CB     1 
ATOM   7858  C CG     . LEU B 1 37  ? -16.663 20.200  -43.087 1.00 25.06  ? 37  LEU B CG     1 
ATOM   7859  C CD1    . LEU B 1 37  ? -17.150 20.876  -44.372 1.00 19.88  ? 37  LEU B CD1    1 
ATOM   7860  C CD2    . LEU B 1 37  ? -17.107 18.744  -43.064 1.00 25.20  ? 37  LEU B CD2    1 
ATOM   7861  H H      . LEU B 1 37  ? -14.597 21.632  -40.904 1.00 24.13  ? 37  LEU B H      1 
ATOM   7862  H HA     . LEU B 1 37  ? -14.981 19.009  -41.435 1.00 23.72  ? 37  LEU B HA     1 
ATOM   7863  H HB2    . LEU B 1 37  ? -14.914 21.249  -43.111 1.00 26.40  ? 37  LEU B HB2    1 
ATOM   7864  H HB3    . LEU B 1 37  ? -14.770 19.798  -43.729 1.00 26.40  ? 37  LEU B HB3    1 
ATOM   7865  H HG     . LEU B 1 37  ? -17.066 20.655  -42.331 1.00 30.07  ? 37  LEU B HG     1 
ATOM   7866  H HD11   . LEU B 1 37  ? -18.116 20.803  -44.420 1.00 23.86  ? 37  LEU B HD11   1 
ATOM   7867  H HD12   . LEU B 1 37  ? -16.889 21.810  -44.355 1.00 23.86  ? 37  LEU B HD12   1 
ATOM   7868  H HD13   . LEU B 1 37  ? -16.746 20.432  -45.134 1.00 23.86  ? 37  LEU B HD13   1 
ATOM   7869  H HD21   . LEU B 1 37  ? -18.038 18.694  -43.331 1.00 30.24  ? 37  LEU B HD21   1 
ATOM   7870  H HD22   . LEU B 1 37  ? -16.558 18.238  -43.683 1.00 30.24  ? 37  LEU B HD22   1 
ATOM   7871  H HD23   . LEU B 1 37  ? -17.002 18.394  -42.166 1.00 30.24  ? 37  LEU B HD23   1 
ATOM   7872  N N      . LEU B 1 38  ? -12.142 20.082  -41.167 1.00 17.92  ? 38  LEU B N      1 
ATOM   7873  C CA     . LEU B 1 38  ? -10.729 19.707  -41.276 1.00 17.57  ? 38  LEU B CA     1 
ATOM   7874  C C      . LEU B 1 38  ? -10.511 18.315  -40.711 1.00 17.95  ? 38  LEU B C      1 
ATOM   7875  O O      . LEU B 1 38  ? -11.116 17.940  -39.706 1.00 18.50  ? 38  LEU B O      1 
ATOM   7876  C CB     . LEU B 1 38  ? -9.820  20.706  -40.548 1.00 18.61  ? 38  LEU B CB     1 
ATOM   7877  C CG     . LEU B 1 38  ? -9.615  22.057  -41.243 1.00 18.80  ? 38  LEU B CG     1 
ATOM   7878  C CD1    . LEU B 1 38  ? -8.929  23.061  -40.330 1.00 18.83  ? 38  LEU B CD1    1 
ATOM   7879  C CD2    . LEU B 1 38  ? -8.814  21.869  -42.521 1.00 18.57  ? 38  LEU B CD2    1 
ATOM   7880  H H      . LEU B 1 38  ? -12.305 20.708  -40.600 1.00 21.51  ? 38  LEU B H      1 
ATOM   7881  H HA     . LEU B 1 38  ? -10.476 19.693  -42.212 1.00 21.09  ? 38  LEU B HA     1 
ATOM   7882  H HB2    . LEU B 1 38  ? -10.202 20.885  -39.675 1.00 22.33  ? 38  LEU B HB2    1 
ATOM   7883  H HB3    . LEU B 1 38  ? -8.946  20.300  -40.440 1.00 22.33  ? 38  LEU B HB3    1 
ATOM   7884  H HG     . LEU B 1 38  ? -10.481 22.419  -41.486 1.00 22.55  ? 38  LEU B HG     1 
ATOM   7885  H HD11   . LEU B 1 38  ? -8.822  23.899  -40.807 1.00 22.60  ? 38  LEU B HD11   1 
ATOM   7886  H HD12   . LEU B 1 38  ? -9.477  23.196  -39.541 1.00 22.60  ? 38  LEU B HD12   1 
ATOM   7887  H HD13   . LEU B 1 38  ? -8.061  22.713  -40.074 1.00 22.60  ? 38  LEU B HD13   1 
ATOM   7888  H HD21   . LEU B 1 38  ? -8.575  22.740  -42.874 1.00 22.28  ? 38  LEU B HD21   1 
ATOM   7889  H HD22   . LEU B 1 38  ? -8.012  21.362  -42.319 1.00 22.28  ? 38  LEU B HD22   1 
ATOM   7890  H HD23   . LEU B 1 38  ? -9.355  21.388  -43.167 1.00 22.28  ? 38  LEU B HD23   1 
ATOM   7891  N N      . ASN B 1 39  ? -9.651  17.549  -41.372 1.00 17.84  ? 39  ASN B N      1 
ATOM   7892  C CA     . ASN B 1 39  ? -9.205  16.269  -40.836 1.00 18.28  ? 39  ASN B CA     1 
ATOM   7893  C C      . ASN B 1 39  ? -8.208  16.518  -39.714 1.00 17.41  ? 39  ASN B C      1 
ATOM   7894  O O      . ASN B 1 39  ? -7.343  17.386  -39.822 1.00 17.31  ? 39  ASN B O      1 
ATOM   7895  C CB     . ASN B 1 39  ? -8.556  15.407  -41.922 1.00 20.22  ? 39  ASN B CB     1 
ATOM   7896  C CG     . ASN B 1 39  ? -9.517  15.038  -43.048 1.00 22.18  ? 39  ASN B CG     1 
ATOM   7897  O OD1    . ASN B 1 39  ? -10.707 14.831  -42.834 1.00 22.77  ? 39  ASN B OD1    1 
ATOM   7898  N ND2    . ASN B 1 39  ? -8.988  14.953  -44.261 1.00 28.61  ? 39  ASN B ND2    1 
ATOM   7899  H H      . ASN B 1 39  ? -9.310  17.748  -42.136 1.00 21.41  ? 39  ASN B H      1 
ATOM   7900  H HA     . ASN B 1 39  ? -9.964  15.786  -40.473 1.00 21.93  ? 39  ASN B HA     1 
ATOM   7901  H HB2    . ASN B 1 39  ? -7.815  15.897  -42.311 1.00 24.27  ? 39  ASN B HB2    1 
ATOM   7902  H HB3    . ASN B 1 39  ? -8.235  14.584  -41.523 1.00 24.27  ? 39  ASN B HB3    1 
ATOM   7903  H HD21   . ASN B 1 39  ? -9.484  14.748  -44.933 1.00 34.34  ? 39  ASN B HD21   1 
ATOM   7904  H HD22   . ASN B 1 39  ? -8.149  15.102  -44.376 1.00 34.34  ? 39  ASN B HD22   1 
ATOM   7905  N N      . SER B 1 40  ? -8.314  15.740  -38.647 1.00 16.91  ? 40  SER B N      1 
ATOM   7906  C CA     . SER B 1 40  ? -7.399  15.872  -37.530 1.00 16.19  ? 40  SER B CA     1 
ATOM   7907  C C      . SER B 1 40  ? -5.950  15.737  -37.984 1.00 18.92  ? 40  SER B C      1 
ATOM   7908  O O      . SER B 1 40  ? -5.067  16.421  -37.469 1.00 16.26  ? 40  SER B O      1 
ATOM   7909  C CB     . SER B 1 40  ? -7.724  14.827  -36.458 1.00 18.67  ? 40  SER B CB     1 
ATOM   7910  O OG     . SER B 1 40  ? -6.790  14.898  -35.407 1.00 19.24  ? 40  SER B OG     1 
ATOM   7911  H H      . SER B 1 40  ? -8.909  15.127  -38.547 1.00 20.29  ? 40  SER B H      1 
ATOM   7912  H HA     . SER B 1 40  ? -7.508  16.751  -37.135 1.00 19.43  ? 40  SER B HA     1 
ATOM   7913  H HB2    . SER B 1 40  ? -8.611  14.999  -36.106 1.00 22.40  ? 40  SER B HB2    1 
ATOM   7914  H HB3    . SER B 1 40  ? -7.689  13.945  -36.858 1.00 22.40  ? 40  SER B HB3    1 
ATOM   7915  H HG     . SER B 1 40  ? -6.992  14.348  -34.805 1.00 23.09  ? 40  SER B HG     1 
ATOM   7916  N N      . LYS B 1 41  ? -5.698  14.882  -38.971 1.00 17.32  ? 41  LYS B N      1 
ATOM   7917  C CA     . LYS B 1 41  ? -4.319  14.647  -39.401 1.00 21.58  ? 41  LYS B CA     1 
ATOM   7918  C C      . LYS B 1 41  ? -3.696  15.893  -40.056 1.00 19.83  ? 41  LYS B C      1 
ATOM   7919  O O      . LYS B 1 41  ? -2.470  15.995  -40.173 1.00 21.27  ? 41  LYS B O      1 
ATOM   7920  C CB     . LYS B 1 41  ? -4.253  13.459  -40.373 1.00 22.36  ? 41  LYS B CB     1 
ATOM   7921  C CG     . LYS B 1 41  ? -4.870  13.737  -41.726 1.00 25.34  ? 41  LYS B CG     1 
ATOM   7922  C CD     . LYS B 1 41  ? -4.799  12.524  -42.647 1.00 29.88  ? 41  LYS B CD     1 
ATOM   7923  C CE     . LYS B 1 41  ? -5.431  12.819  -43.988 1.00 36.22  ? 41  LYS B CE     1 
ATOM   7924  N NZ     . LYS B 1 41  ? -5.358  11.622  -44.867 1.00 58.79  ? 41  LYS B NZ     1 
ATOM   7925  H H      . LYS B 1 41  ? -6.292  14.433  -39.401 1.00 20.78  ? 41  LYS B H      1 
ATOM   7926  H HA     . LYS B 1 41  ? -3.784  14.423  -38.624 1.00 25.89  ? 41  LYS B HA     1 
ATOM   7927  H HB2    . LYS B 1 41  ? -3.323  13.223  -40.515 1.00 26.83  ? 41  LYS B HB2    1 
ATOM   7928  H HB3    . LYS B 1 41  ? -4.726  12.708  -39.981 1.00 26.83  ? 41  LYS B HB3    1 
ATOM   7929  H HG2    . LYS B 1 41  ? -5.803  13.973  -41.608 1.00 30.41  ? 41  LYS B HG2    1 
ATOM   7930  H HG3    . LYS B 1 41  ? -4.393  14.463  -42.157 1.00 30.41  ? 41  LYS B HG3    1 
ATOM   7931  H HD2    . LYS B 1 41  ? -3.870  12.287  -42.794 1.00 35.86  ? 41  LYS B HD2    1 
ATOM   7932  H HD3    . LYS B 1 41  ? -5.276  11.783  -42.241 1.00 35.86  ? 41  LYS B HD3    1 
ATOM   7933  H HE2    . LYS B 1 41  ? -6.364  13.052  -43.862 1.00 43.46  ? 41  LYS B HE2    1 
ATOM   7934  H HE3    . LYS B 1 41  ? -4.954  13.546  -44.418 1.00 43.46  ? 41  LYS B HE3    1 
ATOM   7935  H HZ1    . LYS B 1 41  ? -5.731  11.800  -45.655 1.00 70.54  ? 41  LYS B HZ1    1 
ATOM   7936  H HZ2    . LYS B 1 41  ? -4.508  11.390  -44.995 1.00 70.54  ? 41  LYS B HZ2    1 
ATOM   7937  H HZ3    . LYS B 1 41  ? -5.790  10.941  -44.490 1.00 70.54  ? 41  LYS B HZ3    1 
ATOM   7938  N N      . ASP B 1 42  ? -4.529  16.834  -40.484 1.00 17.92  ? 42  ASP B N      1 
ATOM   7939  C CA     . ASP B 1 42  ? -4.019  18.069  -41.086 1.00 19.34  ? 42  ASP B CA     1 
ATOM   7940  C C      . ASP B 1 42  ? -3.917  19.246  -40.108 1.00 20.08  ? 42  ASP B C      1 
ATOM   7941  O O      . ASP B 1 42  ? -3.565  20.350  -40.514 1.00 14.96  ? 42  ASP B O      1 
ATOM   7942  C CB     . ASP B 1 42  ? -4.898  18.478  -42.264 1.00 23.46  ? 42  ASP B CB     1 
ATOM   7943  C CG     . ASP B 1 42  ? -4.880  17.451  -43.385 1.00 28.81  ? 42  ASP B CG     1 
ATOM   7944  O OD1    . ASP B 1 42  ? -3.783  16.943  -43.728 1.00 24.93  ? 42  ASP B OD1    1 
ATOM   7945  O OD2    . ASP B 1 42  ? -5.966  17.143  -43.905 1.00 22.62  ? 42  ASP B OD2    1 
ATOM   7946  H H      . ASP B 1 42  ? -5.387  16.788  -40.441 1.00 21.50  ? 42  ASP B H      1 
ATOM   7947  H HA     . ASP B 1 42  ? -3.130  17.910  -41.438 1.00 23.21  ? 42  ASP B HA     1 
ATOM   7948  H HB2    . ASP B 1 42  ? -5.814  18.574  -41.958 1.00 28.15  ? 42  ASP B HB2    1 
ATOM   7949  H HB3    . ASP B 1 42  ? -4.577  19.320  -42.624 1.00 28.15  ? 42  ASP B HB3    1 
ATOM   7950  N N      . VAL B 1 43  ? -4.206  18.997  -38.834 1.00 19.65  ? 43  VAL B N      1 
ATOM   7951  C CA     . VAL B 1 43  ? -4.149  20.028  -37.797 1.00 16.90  ? 43  VAL B CA     1 
ATOM   7952  C C      . VAL B 1 43  ? -2.931  19.849  -36.889 1.00 18.09  ? 43  VAL B C      1 
ATOM   7953  O O      . VAL B 1 43  ? -2.689  18.773  -36.346 1.00 18.59  ? 43  VAL B O      1 
ATOM   7954  C CB     . VAL B 1 43  ? -5.418  20.015  -36.939 1.00 15.94  ? 43  VAL B CB     1 
ATOM   7955  C CG1    . VAL B 1 43  ? -5.354  21.097  -35.842 1.00 15.26  ? 43  VAL B CG1    1 
ATOM   7956  C CG2    . VAL B 1 43  ? -6.634  20.220  -37.815 1.00 17.48  ? 43  VAL B CG2    1 
ATOM   7957  H H      . VAL B 1 43  ? -4.442  18.226  -38.537 1.00 23.57  ? 43  VAL B H      1 
ATOM   7958  H HA     . VAL B 1 43  ? -4.084  20.902  -38.211 1.00 20.28  ? 43  VAL B HA     1 
ATOM   7959  H HB     . VAL B 1 43  ? -5.500  19.151  -36.506 1.00 19.13  ? 43  VAL B HB     1 
ATOM   7960  H HG11   . VAL B 1 43  ? -6.242  21.221  -35.472 1.00 18.31  ? 43  VAL B HG11   1 
ATOM   7961  H HG12   . VAL B 1 43  ? -4.744  20.809  -35.145 1.00 18.31  ? 43  VAL B HG12   1 
ATOM   7962  H HG13   . VAL B 1 43  ? -5.042  21.927  -36.235 1.00 18.31  ? 43  VAL B HG13   1 
ATOM   7963  H HG21   . VAL B 1 43  ? -7.422  20.279  -37.252 1.00 20.98  ? 43  VAL B HG21   1 
ATOM   7964  H HG22   . VAL B 1 43  ? -6.525  21.042  -38.318 1.00 20.98  ? 43  VAL B HG22   1 
ATOM   7965  H HG23   . VAL B 1 43  ? -6.717  19.469  -38.422 1.00 20.98  ? 43  VAL B HG23   1 
ATOM   7966  N N      . TYR B 1 44  ? -2.186  20.929  -36.719 1.00 16.25  ? 44  TYR B N      1 
ATOM   7967  C CA     . TYR B 1 44  ? -0.969  20.943  -35.907 1.00 15.24  ? 44  TYR B CA     1 
ATOM   7968  C C      . TYR B 1 44  ? -1.330  21.106  -34.436 1.00 16.93  ? 44  TYR B C      1 
ATOM   7969  O O      . TYR B 1 44  ? -1.001  20.264  -33.609 1.00 16.23  ? 44  TYR B O      1 
ATOM   7970  C CB     . TYR B 1 44  ? -0.065  22.077  -36.396 1.00 16.00  ? 44  TYR B CB     1 
ATOM   7971  C CG     . TYR B 1 44  ? 1.197   22.369  -35.607 1.00 19.80  ? 44  TYR B CG     1 
ATOM   7972  C CD1    . TYR B 1 44  ? 1.745   21.458  -34.715 1.00 18.34  ? 44  TYR B CD1    1 
ATOM   7973  C CD2    . TYR B 1 44  ? 1.851   23.577  -35.782 1.00 19.46  ? 44  TYR B CD2    1 
ATOM   7974  C CE1    . TYR B 1 44  ? 2.905   21.757  -34.017 1.00 16.45  ? 44  TYR B CE1    1 
ATOM   7975  C CE2    . TYR B 1 44  ? 3.002   23.880  -35.096 1.00 21.37  ? 44  TYR B CE2    1 
ATOM   7976  C CZ     . TYR B 1 44  ? 3.530   22.971  -34.220 1.00 16.96  ? 44  TYR B CZ     1 
ATOM   7977  O OH     . TYR B 1 44  ? 4.678   23.299  -33.545 1.00 19.56  ? 44  TYR B OH     1 
ATOM   7978  H H      . TYR B 1 44  ? -2.367  21.692  -37.073 1.00 19.49  ? 44  TYR B H      1 
ATOM   7979  H HA     . TYR B 1 44  ? -0.495  20.104  -36.017 1.00 18.28  ? 44  TYR B HA     1 
ATOM   7980  H HB2    . TYR B 1 44  ? 0.210   21.869  -37.303 1.00 19.20  ? 44  TYR B HB2    1 
ATOM   7981  H HB3    . TYR B 1 44  ? -0.588  22.894  -36.403 1.00 19.20  ? 44  TYR B HB3    1 
ATOM   7982  H HD1    . TYR B 1 44  ? 1.327   20.638  -34.581 1.00 22.01  ? 44  TYR B HD1    1 
ATOM   7983  H HD2    . TYR B 1 44  ? 1.502   24.199  -36.379 1.00 23.35  ? 44  TYR B HD2    1 
ATOM   7984  H HE1    . TYR B 1 44  ? 3.264   21.140  -33.421 1.00 19.74  ? 44  TYR B HE1    1 
ATOM   7985  H HE2    . TYR B 1 44  ? 3.423   24.699  -35.229 1.00 25.64  ? 44  TYR B HE2    1 
ATOM   7986  H HH     . TYR B 1 44  ? 4.895   22.674  -33.028 1.00 23.47  ? 44  TYR B HH     1 
ATOM   7987  N N      . VAL B 1 45  ? -1.997  22.208  -34.130 1.00 16.46  ? 45  VAL B N      1 
ATOM   7988  C CA     . VAL B 1 45  ? -2.454  22.518  -32.780 1.00 15.29  ? 45  VAL B CA     1 
ATOM   7989  C C      . VAL B 1 45  ? -3.974  22.613  -32.787 1.00 17.70  ? 45  VAL B C      1 
ATOM   7990  O O      . VAL B 1 45  ? -4.533  23.513  -33.404 1.00 16.55  ? 45  VAL B O      1 
ATOM   7991  C CB     . VAL B 1 45  ? -1.833  23.821  -32.291 1.00 15.66  ? 45  VAL B CB     1 
ATOM   7992  C CG1    . VAL B 1 45  ? -2.464  24.278  -30.984 1.00 16.91  ? 45  VAL B CG1    1 
ATOM   7993  C CG2    . VAL B 1 45  ? -0.325  23.655  -32.146 1.00 17.93  ? 45  VAL B CG2    1 
ATOM   7994  H H      . VAL B 1 45  ? -2.205  22.813  -34.705 1.00 19.75  ? 45  VAL B H      1 
ATOM   7995  H HA     . VAL B 1 45  ? -2.197  21.811  -32.169 1.00 18.34  ? 45  VAL B HA     1 
ATOM   7996  H HB     . VAL B 1 45  ? -1.993  24.508  -32.955 1.00 18.80  ? 45  VAL B HB     1 
ATOM   7997  H HG11   . VAL B 1 45  ? -1.881  24.931  -30.566 1.00 20.30  ? 45  VAL B HG11   1 
ATOM   7998  H HG12   . VAL B 1 45  ? -3.327  24.679  -31.171 1.00 20.30  ? 45  VAL B HG12   1 
ATOM   7999  H HG13   . VAL B 1 45  ? -2.572  23.511  -30.400 1.00 20.30  ? 45  VAL B HG13   1 
ATOM   8000  H HG21   . VAL B 1 45  ? 0.054   24.485  -31.817 1.00 21.52  ? 45  VAL B HG21   1 
ATOM   8001  H HG22   . VAL B 1 45  ? -0.146  22.938  -31.518 1.00 21.52  ? 45  VAL B HG22   1 
ATOM   8002  H HG23   . VAL B 1 45  ? 0.054   23.439  -33.012 1.00 21.52  ? 45  VAL B HG23   1 
ATOM   8003  N N      . ASP B 1 46  ? -4.646  21.685  -32.106 1.00 15.49  ? 46  ASP B N      1 
ATOM   8004  C CA     . ASP B 1 46  ? -6.090  21.565  -32.251 1.00 14.22  ? 46  ASP B CA     1 
ATOM   8005  C C      . ASP B 1 46  ? -6.801  22.146  -31.037 1.00 17.07  ? 46  ASP B C      1 
ATOM   8006  O O      . ASP B 1 46  ? -6.884  21.504  -29.992 1.00 16.56  ? 46  ASP B O      1 
ATOM   8007  C CB     . ASP B 1 46  ? -6.502  20.103  -32.467 1.00 13.91  ? 46  ASP B CB     1 
ATOM   8008  C CG     . ASP B 1 46  ? -7.938  19.964  -32.988 1.00 19.81  ? 46  ASP B CG     1 
ATOM   8009  O OD1    . ASP B 1 46  ? -8.641  20.990  -33.093 1.00 15.53  ? 46  ASP B OD1    1 
ATOM   8010  O OD2    . ASP B 1 46  ? -8.365  18.819  -33.285 1.00 20.35  ? 46  ASP B OD2    1 
ATOM   8011  H H      . ASP B 1 46  ? -4.292  21.121  -31.562 1.00 18.58  ? 46  ASP B H      1 
ATOM   8012  H HA     . ASP B 1 46  ? -6.379  22.064  -33.030 1.00 17.07  ? 46  ASP B HA     1 
ATOM   8013  H HB2    . ASP B 1 46  ? -5.907  19.702  -33.120 1.00 16.70  ? 46  ASP B HB2    1 
ATOM   8014  H HB3    . ASP B 1 46  ? -6.439  19.625  -31.625 1.00 16.70  ? 46  ASP B HB3    1 
ATOM   8015  N N      . LEU B 1 47  ? -7.297  23.375  -31.185 1.00 13.45  ? 47  LEU B N      1 
ATOM   8016  C CA     . LEU B 1 47  ? -7.956  24.075  -30.085 1.00 13.26  ? 47  LEU B CA     1 
ATOM   8017  C C      . LEU B 1 47  ? -9.468  24.136  -30.281 1.00 17.15  ? 47  LEU B C      1 
ATOM   8018  O O      . LEU B 1 47  ? -10.141 25.052  -29.801 1.00 15.29  ? 47  LEU B O      1 
ATOM   8019  C CB     . LEU B 1 47  ? -7.381  25.487  -29.934 1.00 13.05  ? 47  LEU B CB     1 
ATOM   8020  C CG     . LEU B 1 47  ? -5.857  25.559  -29.841 1.00 15.74  ? 47  LEU B CG     1 
ATOM   8021  C CD1    . LEU B 1 47  ? -5.391  26.992  -29.614 1.00 15.48  ? 47  LEU B CD1    1 
ATOM   8022  C CD2    . LEU B 1 47  ? -5.343  24.656  -28.720 1.00 15.36  ? 47  LEU B CD2    1 
ATOM   8023  H H      . LEU B 1 47  ? -7.264  23.826  -31.916 1.00 16.13  ? 47  LEU B H      1 
ATOM   8024  H HA     . LEU B 1 47  ? -7.788  23.600  -29.258 1.00 15.91  ? 47  LEU B HA     1 
ATOM   8025  H HB2    . LEU B 1 47  ? -7.653  26.015  -30.701 1.00 15.66  ? 47  LEU B HB2    1 
ATOM   8026  H HB3    . LEU B 1 47  ? -7.741  25.881  -29.124 1.00 15.66  ? 47  LEU B HB3    1 
ATOM   8027  H HG     . LEU B 1 47  ? -5.475  25.248  -30.676 1.00 18.89  ? 47  LEU B HG     1 
ATOM   8028  H HD11   . LEU B 1 47  ? -4.422  27.004  -29.563 1.00 18.58  ? 47  LEU B HD11   1 
ATOM   8029  H HD12   . LEU B 1 47  ? -5.690  27.542  -30.355 1.00 18.58  ? 47  LEU B HD12   1 
ATOM   8030  H HD13   . LEU B 1 47  ? -5.771  27.319  -28.784 1.00 18.58  ? 47  LEU B HD13   1 
ATOM   8031  H HD21   . LEU B 1 47  ? -4.399  24.831  -28.583 1.00 18.43  ? 47  LEU B HD21   1 
ATOM   8032  H HD22   . LEU B 1 47  ? -5.837  24.850  -27.908 1.00 18.43  ? 47  LEU B HD22   1 
ATOM   8033  H HD23   . LEU B 1 47  ? -5.474  23.729  -28.974 1.00 18.43  ? 47  LEU B HD23   1 
ATOM   8034  N N      . LEU B 1 48  ? -9.996  23.144  -30.985 1.00 16.32  ? 48  LEU B N      1 
ATOM   8035  C CA     . LEU B 1 48  ? -11.426 23.030  -31.201 1.00 13.44  ? 48  LEU B CA     1 
ATOM   8036  C C      . LEU B 1 48  ? -12.173 22.897  -29.873 1.00 16.76  ? 48  LEU B C      1 
ATOM   8037  O O      . LEU B 1 48  ? -13.210 23.522  -29.667 1.00 17.90  ? 48  LEU B O      1 
ATOM   8038  C CB     . LEU B 1 48  ? -11.717 21.832  -32.108 1.00 19.07  ? 48  LEU B CB     1 
ATOM   8039  C CG     . LEU B 1 48  ? -13.082 21.787  -32.780 1.00 20.23  ? 48  LEU B CG     1 
ATOM   8040  C CD1    . LEU B 1 48  ? -13.295 22.974  -33.718 1.00 20.90  ? 48  LEU B CD1    1 
ATOM   8041  C CD2    . LEU B 1 48  ? -13.223 20.486  -33.543 1.00 18.31  ? 48  LEU B CD2    1 
ATOM   8042  H H      . LEU B 1 48  ? -9.539  22.515  -31.352 1.00 19.59  ? 48  LEU B H      1 
ATOM   8043  H HA     . LEU B 1 48  ? -11.740 23.834  -31.642 1.00 16.13  ? 48  LEU B HA     1 
ATOM   8044  H HB2    . LEU B 1 48  ? -11.053 21.821  -32.814 1.00 22.89  ? 48  LEU B HB2    1 
ATOM   8045  H HB3    . LEU B 1 48  ? -11.633 21.024  -31.578 1.00 22.89  ? 48  LEU B HB3    1 
ATOM   8046  H HG     . LEU B 1 48  ? -13.771 21.811  -32.099 1.00 24.27  ? 48  LEU B HG     1 
ATOM   8047  H HD11   . LEU B 1 48  ? -14.162 22.886  -34.143 1.00 25.08  ? 48  LEU B HD11   1 
ATOM   8048  H HD12   . LEU B 1 48  ? -13.260 23.796  -33.208 1.00 25.08  ? 48  LEU B HD12   1 
ATOM   8049  H HD13   . LEU B 1 48  ? -12.596 22.972  -34.391 1.00 25.08  ? 48  LEU B HD13   1 
ATOM   8050  H HD21   . LEU B 1 48  ? -14.105 20.451  -33.946 1.00 21.97  ? 48  LEU B HD21   1 
ATOM   8051  H HD22   . LEU B 1 48  ? -12.542 20.449  -34.232 1.00 21.97  ? 48  LEU B HD22   1 
ATOM   8052  H HD23   . LEU B 1 48  ? -13.111 19.745  -32.927 1.00 21.97  ? 48  LEU B HD23   1 
ATOM   8053  N N      . THR B 1 49  ? -11.644 22.085  -28.965 1.00 15.78  ? 49  THR B N      1 
ATOM   8054  C CA     . THR B 1 49  ? -12.282 21.915  -27.666 1.00 13.89  ? 49  THR B CA     1 
ATOM   8055  C C      . THR B 1 49  ? -11.318 21.367  -26.621 1.00 17.44  ? 49  THR B C      1 
ATOM   8056  O O      . THR B 1 49  ? -10.335 20.712  -26.967 1.00 16.60  ? 49  THR B O      1 
ATOM   8057  C CB     . THR B 1 49  ? -13.486 20.969  -27.751 1.00 19.86  ? 49  THR B CB     1 
ATOM   8058  O OG1    . THR B 1 49  ? -14.069 20.831  -26.455 1.00 18.07  ? 49  THR B OG1    1 
ATOM   8059  C CG2    . THR B 1 49  ? -13.059 19.594  -28.236 1.00 22.76  ? 49  THR B CG2    1 
ATOM   8060  H H      . THR B 1 49  ? -10.925 21.626  -29.074 1.00 18.93  ? 49  THR B H      1 
ATOM   8061  H HA     . THR B 1 49  ? -12.604 22.774  -27.353 1.00 16.66  ? 49  THR B HA     1 
ATOM   8062  H HB     . THR B 1 49  ? -14.142 21.328  -28.369 1.00 23.83  ? 49  THR B HB     1 
ATOM   8063  H HG1    . THR B 1 49  ? -14.324 21.580  -26.173 1.00 21.68  ? 49  THR B HG1    1 
ATOM   8064  H HG21   . THR B 1 49  ? -13.836 19.023  -28.303 1.00 27.31  ? 49  THR B HG21   1 
ATOM   8065  H HG22   . THR B 1 49  ? -12.640 19.664  -29.108 1.00 27.31  ? 49  THR B HG22   1 
ATOM   8066  H HG23   . THR B 1 49  ? -12.432 19.194  -27.614 1.00 27.31  ? 49  THR B HG23   1 
ATOM   8067  N N      . ASP B 1 50  ? -11.622 21.635  -25.351 1.00 16.80  ? 50  ASP B N      1 
ATOM   8068  C CA     . ASP B 1 50  ? -10.931 21.006  -24.223 1.00 16.72  ? 50  ASP B CA     1 
ATOM   8069  C C      . ASP B 1 50  ? -11.632 19.749  -23.731 1.00 18.70  ? 50  ASP B C      1 
ATOM   8070  O O      . ASP B 1 50  ? -11.268 19.215  -22.683 1.00 18.64  ? 50  ASP B O      1 
ATOM   8071  C CB     . ASP B 1 50  ? -10.809 21.983  -23.047 1.00 18.39  ? 50  ASP B CB     1 
ATOM   8072  C CG     . ASP B 1 50  ? -12.149 22.295  -22.407 1.00 20.03  ? 50  ASP B CG     1 
ATOM   8073  O OD1    . ASP B 1 50  ? -13.158 22.396  -23.138 1.00 17.10  ? 50  ASP B OD1    1 
ATOM   8074  O OD2    . ASP B 1 50  ? -12.192 22.448  -21.169 1.00 18.16  ? 50  ASP B OD2    1 
ATOM   8075  H H      . ASP B 1 50  ? -12.236 22.188  -25.112 1.00 20.16  ? 50  ASP B H      1 
ATOM   8076  H HA     . ASP B 1 50  ? -10.034 20.759  -24.496 1.00 20.06  ? 50  ASP B HA     1 
ATOM   8077  H HB2    . ASP B 1 50  ? -10.235 21.593  -22.369 1.00 22.06  ? 50  ASP B HB2    1 
ATOM   8078  H HB3    . ASP B 1 50  ? -10.428 22.816  -23.366 1.00 22.06  ? 50  ASP B HB3    1 
ATOM   8079  N N      . SER B 1 51  ? -12.643 19.285  -24.460 1.00 18.02  ? 51  SER B N      1 
ATOM   8080  C CA     . SER B 1 51  ? -13.405 18.107  -24.032 1.00 17.27  ? 51  SER B CA     1 
ATOM   8081  C C      . SER B 1 51  ? -12.863 16.815  -24.624 1.00 20.22  ? 51  SER B C      1 
ATOM   8082  O O      . SER B 1 51  ? -12.953 16.583  -25.836 1.00 18.01  ? 51  SER B O      1 
ATOM   8083  C CB     . SER B 1 51  ? -14.875 18.239  -24.412 1.00 21.89  ? 51  SER B CB     1 
ATOM   8084  O OG     . SER B 1 51  ? -15.596 17.104  -23.947 1.00 22.01  ? 51  SER B OG     1 
ATOM   8085  H H      . SER B 1 51  ? -12.910 19.627  -25.202 1.00 21.63  ? 51  SER B H      1 
ATOM   8086  H HA     . SER B 1 51  ? -13.361 18.031  -23.066 1.00 20.72  ? 51  SER B HA     1 
ATOM   8087  H HB2    . SER B 1 51  ? -15.237 19.045  -24.017 1.00 26.27  ? 51  SER B HB2    1 
ATOM   8088  H HB3    . SER B 1 51  ? -14.947 18.283  -25.378 1.00 26.27  ? 51  SER B HB3    1 
ATOM   8089  H HG     . SER B 1 51  ? -16.409 17.180  -24.144 1.00 26.41  ? 51  SER B HG     1 
ATOM   8090  N N      . GLY B 1 52  ? -12.297 15.979  -23.763 1.00 18.06  ? 52  GLY B N      1 
ATOM   8091  C CA     . GLY B 1 52  ? -11.893 14.637  -24.160 1.00 15.69  ? 52  GLY B CA     1 
ATOM   8092  C C      . GLY B 1 52  ? -10.591 14.580  -24.938 1.00 16.82  ? 52  GLY B C      1 
ATOM   8093  O O      . GLY B 1 52  ? -10.205 13.530  -25.445 1.00 15.65  ? 52  GLY B O      1 
ATOM   8094  H H      . GLY B 1 52  ? -12.135 16.165  -22.939 1.00 21.68  ? 52  GLY B H      1 
ATOM   8095  H HA2    . GLY B 1 52  ? -11.794 14.091  -23.365 1.00 18.83  ? 52  GLY B HA2    1 
ATOM   8096  H HA3    . GLY B 1 52  ? -12.590 14.245  -24.710 1.00 18.83  ? 52  GLY B HA3    1 
ATOM   8097  N N      . THR B 1 53  ? -9.910  15.719  -25.009 1.00 14.51  ? 53  THR B N      1 
ATOM   8098  C CA     . THR B 1 53  ? -8.687  15.870  -25.789 1.00 16.31  ? 53  THR B CA     1 
ATOM   8099  C C      . THR B 1 53  ? -7.430  15.887  -24.904 1.00 17.46  ? 53  THR B C      1 
ATOM   8100  O O      . THR B 1 53  ? -6.325  16.074  -25.404 1.00 15.81  ? 53  THR B O      1 
ATOM   8101  C CB     . THR B 1 53  ? -8.734  17.175  -26.591 1.00 19.61  ? 53  THR B CB     1 
ATOM   8102  O OG1    . THR B 1 53  ? -9.128  18.228  -25.704 1.00 16.03  ? 53  THR B OG1    1 
ATOM   8103  C CG2    . THR B 1 53  ? -9.743  17.085  -27.752 1.00 18.30  ? 53  THR B CG2    1 
ATOM   8104  H H      . THR B 1 53  ? -10.141 16.440  -24.602 1.00 17.41  ? 53  THR B H      1 
ATOM   8105  H HA     . THR B 1 53  ? -8.606  15.135  -26.416 1.00 19.57  ? 53  THR B HA     1 
ATOM   8106  H HB     . THR B 1 53  ? -7.857  17.368  -26.958 1.00 23.53  ? 53  THR B HB     1 
ATOM   8107  H HG1    . THR B 1 53  ? -9.213  18.946  -26.131 1.00 19.24  ? 53  THR B HG1    1 
ATOM   8108  H HG21   . THR B 1 53  ? -9.772  17.928  -28.232 1.00 21.96  ? 53  THR B HG21   1 
ATOM   8109  H HG22   . THR B 1 53  ? -9.480  16.382  -28.366 1.00 21.96  ? 53  THR B HG22   1 
ATOM   8110  H HG23   . THR B 1 53  ? -10.628 16.888  -27.407 1.00 21.96  ? 53  THR B HG23   1 
ATOM   8111  N N      . ASN B 1 54  ? -7.608  15.658  -23.602 1.00 15.16  ? 54  ASN B N      1 
ATOM   8112  C CA     . ASN B 1 54  ? -6.531  15.757  -22.624 1.00 12.18  ? 54  ASN B CA     1 
ATOM   8113  C C      . ASN B 1 54  ? -5.465  14.682  -22.782 1.00 15.73  ? 54  ASN B C      1 
ATOM   8114  O O      . ASN B 1 54  ? -5.744  13.597  -23.287 1.00 16.33  ? 54  ASN B O      1 
ATOM   8115  C CB     . ASN B 1 54  ? -7.102  15.675  -21.209 1.00 11.86  ? 54  ASN B CB     1 
ATOM   8116  C CG     . ASN B 1 54  ? -8.291  16.582  -21.013 1.00 16.25  ? 54  ASN B CG     1 
ATOM   8117  O OD1    . ASN B 1 54  ? -8.168  17.806  -21.097 1.00 16.33  ? 54  ASN B OD1    1 
ATOM   8118  N ND2    . ASN B 1 54  ? -9.450  15.989  -20.753 1.00 14.40  ? 54  ASN B ND2    1 
ATOM   8119  H H      . ASN B 1 54  ? -8.362  15.434  -23.256 1.00 18.19  ? 54  ASN B H      1 
ATOM   8120  H HA     . ASN B 1 54  ? -6.099  16.620  -22.721 1.00 14.62  ? 54  ASN B HA     1 
ATOM   8121  H HB2    . ASN B 1 54  ? -7.386  14.764  -21.034 1.00 14.24  ? 54  ASN B HB2    1 
ATOM   8122  H HB3    . ASN B 1 54  ? -6.416  15.937  -20.575 1.00 14.24  ? 54  ASN B HB3    1 
ATOM   8123  H HD21   . ASN B 1 54  ? -10.158 16.463  -20.632 1.00 17.28  ? 54  ASN B HD21   1 
ATOM   8124  H HD22   . ASN B 1 54  ? -9.493  15.131  -20.705 1.00 17.28  ? 54  ASN B HD22   1 
ATOM   8125  N N      . ALA B 1 55  ? -4.248  14.992  -22.347 1.00 14.88  ? 55  ALA B N      1 
ATOM   8126  C CA     . ALA B 1 55  ? -3.182  13.997  -22.287 1.00 13.90  ? 55  ALA B CA     1 
ATOM   8127  C C      . ALA B 1 55  ? -3.249  13.318  -20.930 1.00 16.07  ? 55  ALA B C      1 
ATOM   8128  O O      . ALA B 1 55  ? -3.244  13.998  -19.898 1.00 13.72  ? 55  ALA B O      1 
ATOM   8129  C CB     . ALA B 1 55  ? -1.815  14.642  -22.500 1.00 17.06  ? 55  ALA B CB     1 
ATOM   8130  H H      . ALA B 1 55  ? -4.013  15.775  -22.080 1.00 17.86  ? 55  ALA B H      1 
ATOM   8131  H HA     . ALA B 1 55  ? -3.314  13.327  -22.976 1.00 16.68  ? 55  ALA B HA     1 
ATOM   8132  H HB1    . ALA B 1 55  ? -1.132  13.955  -22.454 1.00 20.47  ? 55  ALA B HB1    1 
ATOM   8133  H HB2    . ALA B 1 55  ? -1.799  15.067  -23.372 1.00 20.47  ? 55  ALA B HB2    1 
ATOM   8134  H HB3    . ALA B 1 55  ? -1.667  15.303  -21.806 1.00 20.47  ? 55  ALA B HB3    1 
ATOM   8135  N N      . MET B 1 56  ? -3.304  11.988  -20.930 1.00 15.21  ? 56  MET B N      1 
ATOM   8136  C CA     . MET B 1 56  ? -3.294  11.224  -19.687 1.00 12.80  ? 56  MET B CA     1 
ATOM   8137  C C      . MET B 1 56  ? -1.861  11.050  -19.193 1.00 13.55  ? 56  MET B C      1 
ATOM   8138  O O      . MET B 1 56  ? -0.910  11.280  -19.935 1.00 14.73  ? 56  MET B O      1 
ATOM   8139  C CB     . MET B 1 56  ? -3.962  9.864   -19.882 1.00 15.72  ? 56  MET B CB     1 
ATOM   8140  C CG     . MET B 1 56  ? -5.452  9.972   -20.161 1.00 18.45  ? 56  MET B CG     1 
ATOM   8141  S SD     . MET B 1 56  ? -6.342  8.456   -19.837 1.00 17.02  ? 56  MET B SD     1 
ATOM   8142  C CE     . MET B 1 56  ? -5.746  7.447   -21.168 1.00 17.37  ? 56  MET B CE     1 
ATOM   8143  H H      . MET B 1 56  ? -3.348  11.504  -21.639 1.00 18.26  ? 56  MET B H      1 
ATOM   8144  H HA     . MET B 1 56  ? -3.801  11.712  -19.021 1.00 15.36  ? 56  MET B HA     1 
ATOM   8145  H HB2    . MET B 1 56  ? -3.548  9.414   -20.635 1.00 18.86  ? 56  MET B HB2    1 
ATOM   8146  H HB3    . MET B 1 56  ? -3.846  9.337   -19.076 1.00 18.86  ? 56  MET B HB3    1 
ATOM   8147  H HG2    . MET B 1 56  ? -5.828  10.665  -19.596 1.00 22.14  ? 56  MET B HG2    1 
ATOM   8148  H HG3    . MET B 1 56  ? -5.581  10.200  -21.095 1.00 22.14  ? 56  MET B HG3    1 
ATOM   8149  H HE1    . MET B 1 56  ? -6.162  6.573   -21.111 1.00 20.84  ? 56  MET B HE1    1 
ATOM   8150  H HE2    . MET B 1 56  ? -5.975  7.869   -22.011 1.00 20.84  ? 56  MET B HE2    1 
ATOM   8151  H HE3    . MET B 1 56  ? -4.783  7.361   -21.092 1.00 20.84  ? 56  MET B HE3    1 
ATOM   8152  N N      . SER B 1 57  ? -1.720  10.669  -17.929 1.00 11.93  ? 57  SER B N      1 
ATOM   8153  C CA     . SER B 1 57  ? -0.421  10.389  -17.338 1.00 12.16  ? 57  SER B CA     1 
ATOM   8154  C C      . SER B 1 57  ? 0.019   8.943   -17.523 1.00 14.94  ? 57  SER B C      1 
ATOM   8155  O O      . SER B 1 57  ? -0.774  8.074   -17.893 1.00 13.81  ? 57  SER B O      1 
ATOM   8156  C CB     . SER B 1 57  ? -0.458  10.688  -15.845 1.00 14.88  ? 57  SER B CB     1 
ATOM   8157  O OG     . SER B 1 57  ? -1.303  9.752   -15.206 1.00 17.78  ? 57  SER B OG     1 
ATOM   8158  H H      . SER B 1 57  ? -2.376  10.564  -17.384 1.00 14.31  ? 57  SER B H      1 
ATOM   8159  H HA     . SER B 1 57  ? 0.248   10.962  -17.743 1.00 14.59  ? 57  SER B HA     1 
ATOM   8160  H HB2    . SER B 1 57  ? 0.438   10.614  -15.480 1.00 17.85  ? 57  SER B HB2    1 
ATOM   8161  H HB3    . SER B 1 57  ? -0.806  11.583  -15.705 1.00 17.85  ? 57  SER B HB3    1 
ATOM   8162  H HG     . SER B 1 57  ? -1.206  9.800   -14.374 1.00 21.33  ? 57  SER B HG     1 
ATOM   8163  N N      . ASP B 1 58  ? 1.283   8.688   -17.198 1.00 14.87  ? 58  ASP B N      1 
ATOM   8164  C CA     . ASP B 1 58  ? 1.794   7.332   -17.125 1.00 15.78  ? 58  ASP B CA     1 
ATOM   8165  C C      . ASP B 1 58  ? 0.968   6.495   -16.136 1.00 17.49  ? 58  ASP B C      1 
ATOM   8166  O O      . ASP B 1 58  ? 0.635   5.345   -16.417 1.00 16.28  ? 58  ASP B O      1 
ATOM   8167  C CB     . ASP B 1 58  ? 3.288   7.331   -16.744 1.00 15.66  ? 58  ASP B CB     1 
ATOM   8168  C CG     . ASP B 1 58  ? 3.621   8.205   -15.527 1.00 22.97  ? 58  ASP B CG     1 
ATOM   8169  O OD1    . ASP B 1 58  ? 2.729   8.824   -14.915 1.00 17.33  ? 58  ASP B OD1    1 
ATOM   8170  O OD2    . ASP B 1 58  ? 4.819   8.248   -15.167 1.00 25.87  ? 58  ASP B OD2    1 
ATOM   8171  H H      . ASP B 1 58  ? 1.866   9.293   -17.016 1.00 17.84  ? 58  ASP B H      1 
ATOM   8172  H HA     . ASP B 1 58  ? 1.712   6.921   -18.000 1.00 18.93  ? 58  ASP B HA     1 
ATOM   8173  H HB2    . ASP B 1 58  ? 3.557   6.422   -16.538 1.00 18.79  ? 58  ASP B HB2    1 
ATOM   8174  H HB3    . ASP B 1 58  ? 3.802   7.663   -17.497 1.00 18.79  ? 58  ASP B HB3    1 
ATOM   8175  N N      . LYS B 1 59  ? 0.607   7.081   -15.001 1.00 15.94  ? 59  LYS B N      1 
ATOM   8176  C CA     . LYS B 1 59  ? -0.183  6.360   -14.008 1.00 15.55  ? 59  LYS B CA     1 
ATOM   8177  C C      . LYS B 1 59  ? -1.557  5.983   -14.568 1.00 16.24  ? 59  LYS B C      1 
ATOM   8178  O O      . LYS B 1 59  ? -2.067  4.889   -14.309 1.00 12.57  ? 59  LYS B O      1 
ATOM   8179  C CB     . LYS B 1 59  ? -0.349  7.185   -12.732 1.00 17.79  ? 59  LYS B CB     1 
ATOM   8180  C CG     . LYS B 1 59  ? 0.952   7.611   -12.062 1.00 30.65  ? 59  LYS B CG     1 
ATOM   8181  C CD     . LYS B 1 59  ? 1.612   6.472   -11.317 1.00 43.77  ? 59  LYS B CD     1 
ATOM   8182  C CE     . LYS B 1 59  ? 2.774   6.984   -10.459 1.00 67.15  ? 59  LYS B CE     1 
ATOM   8183  N NZ     . LYS B 1 59  ? 3.421   5.910   -9.645  1.00 84.56  ? 59  LYS B NZ     1 
ATOM   8184  H H      . LYS B 1 59  ? 0.804   7.889   -14.782 1.00 19.13  ? 59  LYS B H      1 
ATOM   8185  H HA     . LYS B 1 59  ? 0.279   5.540   -13.775 1.00 18.66  ? 59  LYS B HA     1 
ATOM   8186  H HB2    . LYS B 1 59  ? -0.843  7.991   -12.949 1.00 21.34  ? 59  LYS B HB2    1 
ATOM   8187  H HB3    . LYS B 1 59  ? -0.851  6.660   -12.089 1.00 21.34  ? 59  LYS B HB3    1 
ATOM   8188  H HG2    . LYS B 1 59  ? 1.571   7.928   -12.738 1.00 36.79  ? 59  LYS B HG2    1 
ATOM   8189  H HG3    . LYS B 1 59  ? 0.764   8.318   -11.425 1.00 36.79  ? 59  LYS B HG3    1 
ATOM   8190  H HD2    . LYS B 1 59  ? 0.962   6.055   -10.730 1.00 52.52  ? 59  LYS B HD2    1 
ATOM   8191  H HD3    . LYS B 1 59  ? 1.955   5.826   -11.949 1.00 52.52  ? 59  LYS B HD3    1 
ATOM   8192  H HE2    . LYS B 1 59  ? 3.449   7.370   -11.038 1.00 80.58  ? 59  LYS B HE2    1 
ATOM   8193  H HE3    . LYS B 1 59  ? 2.439   7.659   -9.848  1.00 80.58  ? 59  LYS B HE3    1 
ATOM   8194  H HZ1    . LYS B 1 59  ? 4.127   6.239   -9.214  1.00 101.47 ? 59  LYS B HZ1    1 
ATOM   8195  H HZ2    . LYS B 1 59  ? 2.842   5.590   -9.050  1.00 101.47 ? 59  LYS B HZ2    1 
ATOM   8196  H HZ3    . LYS B 1 59  ? 3.689   5.247   -10.173 1.00 101.47 ? 59  LYS B HZ3    1 
ATOM   8197  N N      . GLN B 1 60  ? -2.157  6.881   -15.339 1.00 15.30  ? 60  GLN B N      1 
ATOM   8198  C CA     . GLN B 1 60  ? -3.451  6.595   -15.943 1.00 13.93  ? 60  GLN B CA     1 
ATOM   8199  C C      . GLN B 1 60  ? -3.321  5.470   -16.974 1.00 13.35  ? 60  GLN B C      1 
ATOM   8200  O O      . GLN B 1 60  ? -4.170  4.584   -17.042 1.00 14.74  ? 60  GLN B O      1 
ATOM   8201  C CB     . GLN B 1 60  ? -4.038  7.847   -16.599 1.00 14.10  ? 60  GLN B CB     1 
ATOM   8202  C CG     . GLN B 1 60  ? -4.640  8.830   -15.606 1.00 13.61  ? 60  GLN B CG     1 
ATOM   8203  C CD     . GLN B 1 60  ? -5.105  10.101  -16.292 1.00 16.39  ? 60  GLN B CD     1 
ATOM   8204  O OE1    . GLN B 1 60  ? -4.290  10.875  -16.794 1.00 14.90  ? 60  GLN B OE1    1 
ATOM   8205  N NE2    . GLN B 1 60  ? -6.415  10.305  -16.342 1.00 14.70  ? 60  GLN B NE2    1 
ATOM   8206  H H      . GLN B 1 60  ? -1.839  7.658   -15.527 1.00 18.36  ? 60  GLN B H      1 
ATOM   8207  H HA     . GLN B 1 60  ? -4.066  6.301   -15.252 1.00 16.71  ? 60  GLN B HA     1 
ATOM   8208  H HB2    . GLN B 1 60  ? -3.333  8.307   -17.081 1.00 16.92  ? 60  GLN B HB2    1 
ATOM   8209  H HB3    . GLN B 1 60  ? -4.738  7.579   -17.215 1.00 16.92  ? 60  GLN B HB3    1 
ATOM   8210  H HG2    . GLN B 1 60  ? -5.406  8.420   -15.174 1.00 16.33  ? 60  GLN B HG2    1 
ATOM   8211  H HG3    . GLN B 1 60  ? -3.970  9.069   -14.946 1.00 16.33  ? 60  GLN B HG3    1 
ATOM   8212  H HE21   . GLN B 1 60  ? -6.953  9.730   -15.996 1.00 17.65  ? 60  GLN B HE21   1 
ATOM   8213  H HE22   . GLN B 1 60  ? -6.726  11.012  -16.720 1.00 17.65  ? 60  GLN B HE22   1 
ATOM   8214  N N      . TRP B 1 61  ? -2.261  5.505   -17.776 1.00 14.20  ? 61  TRP B N      1 
ATOM   8215  C CA     . TRP B 1 61  ? -2.056  4.471   -18.784 1.00 16.49  ? 61  TRP B CA     1 
ATOM   8216  C C      . TRP B 1 61  ? -1.733  3.126   -18.133 1.00 16.48  ? 61  TRP B C      1 
ATOM   8217  O O      . TRP B 1 61  ? -2.092  2.082   -18.673 1.00 13.79  ? 61  TRP B O      1 
ATOM   8218  C CB     . TRP B 1 61  ? -0.962  4.889   -19.784 1.00 14.98  ? 61  TRP B CB     1 
ATOM   8219  C CG     . TRP B 1 61  ? -1.546  5.707   -20.903 1.00 13.40  ? 61  TRP B CG     1 
ATOM   8220  C CD1    . TRP B 1 61  ? -1.503  7.073   -21.050 1.00 15.45  ? 61  TRP B CD1    1 
ATOM   8221  C CD2    . TRP B 1 61  ? -2.309  5.208   -22.008 1.00 14.79  ? 61  TRP B CD2    1 
ATOM   8222  N NE1    . TRP B 1 61  ? -2.188  7.440   -22.189 1.00 16.34  ? 61  TRP B NE1    1 
ATOM   8223  C CE2    . TRP B 1 61  ? -2.685  6.322   -22.788 1.00 16.95  ? 61  TRP B CE2    1 
ATOM   8224  C CE3    . TRP B 1 61  ? -2.707  3.929   -22.407 1.00 19.96  ? 61  TRP B CE3    1 
ATOM   8225  C CZ2    . TRP B 1 61  ? -3.442  6.181   -23.954 1.00 16.95  ? 61  TRP B CZ2    1 
ATOM   8226  C CZ3    . TRP B 1 61  ? -3.453  3.798   -23.551 1.00 19.25  ? 61  TRP B CZ3    1 
ATOM   8227  C CH2    . TRP B 1 61  ? -3.814  4.915   -24.316 1.00 16.63  ? 61  TRP B CH2    1 
ATOM   8228  H H      . TRP B 1 61  ? -1.651  6.111   -17.757 1.00 17.03  ? 61  TRP B H      1 
ATOM   8229  H HA     . TRP B 1 61  ? -2.880  4.362   -19.284 1.00 19.79  ? 61  TRP B HA     1 
ATOM   8230  H HB2    . TRP B 1 61  ? -0.296  5.426   -19.327 1.00 17.98  ? 61  TRP B HB2    1 
ATOM   8231  H HB3    . TRP B 1 61  ? -0.554  4.096   -20.165 1.00 17.98  ? 61  TRP B HB3    1 
ATOM   8232  H HD1    . TRP B 1 61  ? -1.075  7.661   -20.470 1.00 18.54  ? 61  TRP B HD1    1 
ATOM   8233  H HE1    . TRP B 1 61  ? -2.280  8.244   -22.479 1.00 19.61  ? 61  TRP B HE1    1 
ATOM   8234  H HE3    . TRP B 1 61  ? -2.475  3.182   -21.904 1.00 23.96  ? 61  TRP B HE3    1 
ATOM   8235  H HZ2    . TRP B 1 61  ? -3.683  6.920   -24.465 1.00 20.35  ? 61  TRP B HZ2    1 
ATOM   8236  H HZ3    . TRP B 1 61  ? -3.719  2.951   -23.827 1.00 23.10  ? 61  TRP B HZ3    1 
ATOM   8237  H HH2    . TRP B 1 61  ? -4.314  4.793   -25.091 1.00 19.95  ? 61  TRP B HH2    1 
ATOM   8238  N N      . ALA B 1 62  ? -1.069  3.140   -16.982 1.00 14.48  ? 62  ALA B N      1 
ATOM   8239  C CA     . ALA B 1 62  ? -0.880  1.902   -16.223 1.00 16.03  ? 62  ALA B CA     1 
ATOM   8240  C C      . ALA B 1 62  ? -2.253  1.352   -15.829 1.00 15.55  ? 62  ALA B C      1 
ATOM   8241  O O      . ALA B 1 62  ? -2.517  0.149   -15.929 1.00 16.17  ? 62  ALA B O      1 
ATOM   8242  C CB     . ALA B 1 62  ? -0.007  2.143   -14.985 1.00 14.80  ? 62  ALA B CB     1 
ATOM   8243  H H      . ALA B 1 62  ? -0.722  3.839   -16.621 1.00 17.38  ? 62  ALA B H      1 
ATOM   8244  H HA     . ALA B 1 62  ? -0.438  1.246   -16.784 1.00 19.24  ? 62  ALA B HA     1 
ATOM   8245  H HB1    . ALA B 1 62  ? 0.106   1.305   -14.511 1.00 17.76  ? 62  ALA B HB1    1 
ATOM   8246  H HB2    . ALA B 1 62  ? 0.856   2.482   -15.270 1.00 17.76  ? 62  ALA B HB2    1 
ATOM   8247  H HB3    . ALA B 1 62  ? -0.445  2.792   -14.412 1.00 17.76  ? 62  ALA B HB3    1 
ATOM   8248  N N      . GLY B 1 63  ? -3.140  2.256   -15.405 1.00 15.12  ? 63  GLY B N      1 
ATOM   8249  C CA     . GLY B 1 63  ? -4.500  1.888   -15.066 1.00 15.73  ? 63  GLY B CA     1 
ATOM   8250  C C      . GLY B 1 63  ? -5.236  1.317   -16.256 1.00 18.03  ? 63  GLY B C      1 
ATOM   8251  O O      . GLY B 1 63  ? -6.057  0.414   -16.110 1.00 18.84  ? 63  GLY B O      1 
ATOM   8252  H H      . GLY B 1 63  ? -2.970  3.093   -15.307 1.00 18.14  ? 63  GLY B H      1 
ATOM   8253  H HA2    . GLY B 1 63  ? -4.491  1.224   -14.359 1.00 18.88  ? 63  GLY B HA2    1 
ATOM   8254  H HA3    . GLY B 1 63  ? -4.980  2.670   -14.751 1.00 18.88  ? 63  GLY B HA3    1 
ATOM   8255  N N      . MET B 1 64  ? -4.942  1.849   -17.442 1.00 16.01  ? 64  MET B N      1 
ATOM   8256  C CA     . MET B 1 64  ? -5.577  1.398   -18.675 1.00 15.92  ? 64  MET B CA     1 
ATOM   8257  C C      . MET B 1 64  ? -5.221  -0.065  -18.984 1.00 17.62  ? 64  MET B C      1 
ATOM   8258  O O      . MET B 1 64  ? -5.969  -0.741  -19.681 1.00 19.45  ? 64  MET B O      1 
ATOM   8259  C CB     . MET B 1 64  ? -5.161  2.284   -19.851 1.00 18.72  ? 64  MET B CB     1 
ATOM   8260  C CG     . MET B 1 64  ? -5.714  3.698   -19.807 1.00 22.88  ? 64  MET B CG     1 
ATOM   8261  S SD     . MET B 1 64  ? -7.414  3.809   -20.405 1.00 21.27  ? 64  MET B SD     1 
ATOM   8262  C CE     . MET B 1 64  ? -7.201  3.567   -22.150 1.00 23.25  ? 64  MET B CE     1 
ATOM   8263  H H      . MET B 1 64  ? -4.370  2.481   -17.558 1.00 19.21  ? 64  MET B H      1 
ATOM   8264  H HA     . MET B 1 64  ? -6.539  1.471   -18.575 1.00 19.11  ? 64  MET B HA     1 
ATOM   8265  H HB2    . MET B 1 64  ? -4.195  2.348   -19.870 1.00 22.46  ? 64  MET B HB2    1 
ATOM   8266  H HB3    . MET B 1 64  ? -5.473  1.871   -20.671 1.00 22.46  ? 64  MET B HB3    1 
ATOM   8267  H HG2    . MET B 1 64  ? -5.704  4.012   -18.891 1.00 27.45  ? 64  MET B HG2    1 
ATOM   8268  H HG3    . MET B 1 64  ? -5.162  4.271   -20.362 1.00 27.45  ? 64  MET B HG3    1 
ATOM   8269  H HE1    . MET B 1 64  ? -8.075  3.506   -22.566 1.00 27.90  ? 64  MET B HE1    1 
ATOM   8270  H HE2    . MET B 1 64  ? -6.711  4.320   -22.516 1.00 27.90  ? 64  MET B HE2    1 
ATOM   8271  H HE3    . MET B 1 64  ? -6.708  2.746   -22.300 1.00 27.90  ? 64  MET B HE3    1 
ATOM   8272  N N      . MET B 1 65  ? -4.081  -0.537  -18.475 1.00 15.68  ? 65  MET B N      1 
ATOM   8273  C CA     . MET B 1 65  ? -3.666  -1.936  -18.658 1.00 13.66  ? 65  MET B CA     1 
ATOM   8274  C C      . MET B 1 65  ? -4.323  -2.857  -17.627 1.00 16.39  ? 65  MET B C      1 
ATOM   8275  O O      . MET B 1 65  ? -4.249  -4.082  -17.760 1.00 19.90  ? 65  MET B O      1 
ATOM   8276  C CB     . MET B 1 65  ? -2.140  -2.088  -18.540 1.00 16.54  ? 65  MET B CB     1 
ATOM   8277  C CG     . MET B 1 65  ? -1.343  -1.285  -19.533 1.00 19.48  ? 65  MET B CG     1 
ATOM   8278  S SD     . MET B 1 65  ? -1.676  -1.864  -21.193 1.00 27.53  ? 65  MET B SD     1 
ATOM   8279  C CE     . MET B 1 65  ? -2.247  -0.346  -21.917 1.00 25.75  ? 65  MET B CE     1 
ATOM   8280  H H      . MET B 1 65  ? -3.525  -0.067  -18.017 1.00 18.82  ? 65  MET B H      1 
ATOM   8281  H HA     . MET B 1 65  ? -3.926  -2.228  -19.546 1.00 16.40  ? 65  MET B HA     1 
ATOM   8282  H HB2    . MET B 1 65  ? -1.870  -1.807  -17.652 1.00 19.84  ? 65  MET B HB2    1 
ATOM   8283  H HB3    . MET B 1 65  ? -1.912  -3.022  -18.669 1.00 19.84  ? 65  MET B HB3    1 
ATOM   8284  H HG2    . MET B 1 65  ? -1.597  -0.351  -19.475 1.00 23.38  ? 65  MET B HG2    1 
ATOM   8285  H HG3    . MET B 1 65  ? -0.396  -1.392  -19.353 1.00 23.38  ? 65  MET B HG3    1 
ATOM   8286  H HE1    . MET B 1 65  ? -2.423  -0.493  -22.859 1.00 30.90  ? 65  MET B HE1    1 
ATOM   8287  H HE2    . MET B 1 65  ? -3.060  -0.068  -21.467 1.00 30.90  ? 65  MET B HE2    1 
ATOM   8288  H HE3    . MET B 1 65  ? -1.561  0.332   -21.810 1.00 30.90  ? 65  MET B HE3    1 
ATOM   8289  N N      . MET B 1 66  ? -4.948  -2.271  -16.606 1.00 18.25  ? 66  MET B N      1 
ATOM   8290  C CA     . MET B 1 66  ? -5.579  -3.036  -15.519 1.00 21.00  ? 66  MET B CA     1 
ATOM   8291  C C      . MET B 1 66  ? -7.097  -2.903  -15.547 1.00 21.33  ? 66  MET B C      1 
ATOM   8292  O O      . MET B 1 66  ? -7.766  -2.878  -14.499 1.00 19.38  ? 66  MET B O      1 
ATOM   8293  C CB     . MET B 1 66  ? -5.048  -2.576  -14.153 1.00 19.79  ? 66  MET B CB     1 
ATOM   8294  C CG     . MET B 1 66  ? -3.587  -2.908  -13.891 1.00 24.52  ? 66  MET B CG     1 
ATOM   8295  S SD     . MET B 1 66  ? -3.232  -4.664  -13.997 1.00 32.52  ? 66  MET B SD     1 
ATOM   8296  C CE     . MET B 1 66  ? -4.498  -5.358  -12.923 1.00 33.50  ? 66  MET B CE     1 
ATOM   8297  H H      . MET B 1 66  ? -5.024  -1.420  -16.513 1.00 21.89  ? 66  MET B H      1 
ATOM   8298  H HA     . MET B 1 66  ? -5.357  -3.974  -15.618 1.00 25.20  ? 66  MET B HA     1 
ATOM   8299  H HB2    . MET B 1 66  ? -5.140  -1.612  -14.098 1.00 23.75  ? 66  MET B HB2    1 
ATOM   8300  H HB3    . MET B 1 66  ? -5.572  -2.990  -13.451 1.00 23.75  ? 66  MET B HB3    1 
ATOM   8301  H HG2    . MET B 1 66  ? -3.039  -2.452  -14.548 1.00 29.42  ? 66  MET B HG2    1 
ATOM   8302  H HG3    . MET B 1 66  ? -3.351  -2.609  -12.999 1.00 29.42  ? 66  MET B HG3    1 
ATOM   8303  H HE1    . MET B 1 66  ? -4.321  -6.303  -12.798 1.00 40.20  ? 66  MET B HE1    1 
ATOM   8304  H HE2    . MET B 1 66  ? -4.474  -4.898  -12.070 1.00 40.20  ? 66  MET B HE2    1 
ATOM   8305  H HE3    . MET B 1 66  ? -5.366  -5.238  -13.339 1.00 40.20  ? 66  MET B HE3    1 
ATOM   8306  N N      . GLY B 1 67  ? -7.646  -2.810  -16.752 1.00 14.79  ? 67  GLY B N      1 
ATOM   8307  C CA     . GLY B 1 67  ? -9.082  -2.783  -16.916 1.00 15.04  ? 67  GLY B CA     1 
ATOM   8308  C C      . GLY B 1 67  ? -9.677  -4.121  -16.515 1.00 18.49  ? 67  GLY B C      1 
ATOM   8309  O O      . GLY B 1 67  ? -9.304  -5.166  -17.038 1.00 18.64  ? 67  GLY B O      1 
ATOM   8310  H H      . GLY B 1 67  ? -7.204  -2.762  -17.488 1.00 17.75  ? 67  GLY B H      1 
ATOM   8311  H HA2    . GLY B 1 67  ? -9.466  -2.087  -16.360 1.00 18.05  ? 67  GLY B HA2    1 
ATOM   8312  H HA3    . GLY B 1 67  ? -9.306  -2.604  -17.843 1.00 18.05  ? 67  GLY B HA3    1 
ATOM   8313  N N      . ASP B 1 68  ? -10.588 -4.051  -15.553 1.00 16.67  ? 68  ASP B N      1 
ATOM   8314  C CA     . ASP B 1 68  ? -11.396 -5.166  -15.075 1.00 15.95  ? 68  ASP B CA     1 
ATOM   8315  C C      . ASP B 1 68  ? -12.735 -5.031  -15.766 1.00 19.15  ? 68  ASP B C      1 
ATOM   8316  O O      . ASP B 1 68  ? -13.573 -4.225  -15.354 1.00 18.70  ? 68  ASP B O      1 
ATOM   8317  C CB     . ASP B 1 68  ? -11.515 -5.086  -13.542 1.00 16.77  ? 68  ASP B CB     1 
ATOM   8318  C CG     . ASP B 1 68  ? -12.346 -6.203  -12.928 1.00 21.56  ? 68  ASP B CG     1 
ATOM   8319  O OD1    . ASP B 1 68  ? -12.979 -7.003  -13.647 1.00 19.73  ? 68  ASP B OD1    1 
ATOM   8320  O OD2    . ASP B 1 68  ? -12.363 -6.266  -11.677 1.00 20.11  ? 68  ASP B OD2    1 
ATOM   8321  H H      . ASP B 1 68  ? -10.764 -3.320  -15.136 1.00 20.01  ? 68  ASP B H      1 
ATOM   8322  H HA     . ASP B 1 68  ? -10.990 -6.011  -15.322 1.00 19.14  ? 68  ASP B HA     1 
ATOM   8323  H HB2    . ASP B 1 68  ? -10.626 -5.135  -13.158 1.00 20.12  ? 68  ASP B HB2    1 
ATOM   8324  H HB3    . ASP B 1 68  ? -11.929 -4.242  -13.304 1.00 20.12  ? 68  ASP B HB3    1 
ATOM   8325  N N      . GLU B 1 69  ? -12.928 -5.789  -16.839 1.00 15.71  ? 69  GLU B N      1 
ATOM   8326  C CA     . GLU B 1 69  ? -14.023 -5.509  -17.758 1.00 15.17  ? 69  GLU B CA     1 
ATOM   8327  C C      . GLU B 1 69  ? -15.311 -6.251  -17.371 1.00 20.01  ? 69  GLU B C      1 
ATOM   8328  O O      . GLU B 1 69  ? -16.256 -6.336  -18.152 1.00 18.45  ? 69  GLU B O      1 
ATOM   8329  C CB     . GLU B 1 69  ? -13.590 -5.846  -19.188 1.00 16.76  ? 69  GLU B CB     1 
ATOM   8330  C CG     . GLU B 1 69  ? -12.441 -4.955  -19.674 1.00 15.66  ? 69  GLU B CG     1 
ATOM   8331  C CD     . GLU B 1 69  ? -12.794 -3.472  -19.629 1.00 15.91  ? 69  GLU B CD     1 
ATOM   8332  O OE1    . GLU B 1 69  ? -14.001 -3.148  -19.766 1.00 15.93  ? 69  GLU B OE1    1 
ATOM   8333  O OE2    . GLU B 1 69  ? -11.875 -2.630  -19.444 1.00 16.65  ? 69  GLU B OE2    1 
ATOM   8334  H H      . GLU B 1 69  ? -12.444 -6.466  -17.056 1.00 18.85  ? 69  GLU B H      1 
ATOM   8335  H HA     . GLU B 1 69  ? -14.222 -4.562  -17.722 1.00 18.21  ? 69  GLU B HA     1 
ATOM   8336  H HB2    . GLU B 1 69  ? -13.290 -6.768  -19.219 1.00 20.11  ? 69  GLU B HB2    1 
ATOM   8337  H HB3    . GLU B 1 69  ? -14.343 -5.721  -19.787 1.00 20.11  ? 69  GLU B HB3    1 
ATOM   8338  H HG2    . GLU B 1 69  ? -11.667 -5.098  -19.107 1.00 18.79  ? 69  GLU B HG2    1 
ATOM   8339  H HG3    . GLU B 1 69  ? -12.228 -5.186  -20.592 1.00 18.79  ? 69  GLU B HG3    1 
ATOM   8340  N N      . ALA B 1 70  ? -15.366 -6.727  -16.134 1.00 17.13  ? 70  ALA B N      1 
ATOM   8341  C CA     . ALA B 1 70  ? -16.543 -7.434  -15.639 1.00 16.93  ? 70  ALA B CA     1 
ATOM   8342  C C      . ALA B 1 70  ? -17.804 -6.560  -15.639 1.00 17.14  ? 70  ALA B C      1 
ATOM   8343  O O      . ALA B 1 70  ? -17.754 -5.354  -15.389 1.00 17.43  ? 70  ALA B O      1 
ATOM   8344  C CB     . ALA B 1 70  ? -16.278 -7.964  -14.250 1.00 15.33  ? 70  ALA B CB     1 
ATOM   8345  H H      . ALA B 1 70  ? -14.734 -6.655  -15.555 1.00 20.56  ? 70  ALA B H      1 
ATOM   8346  H HA     . ALA B 1 70  ? -16.713 -8.194  -16.217 1.00 20.32  ? 70  ALA B HA     1 
ATOM   8347  H HB1    . ALA B 1 70  ? -17.068 -8.431  -13.935 1.00 18.39  ? 70  ALA B HB1    1 
ATOM   8348  H HB2    . ALA B 1 70  ? -15.524 -8.574  -14.284 1.00 18.39  ? 70  ALA B HB2    1 
ATOM   8349  H HB3    . ALA B 1 70  ? -16.076 -7.220  -13.662 1.00 18.39  ? 70  ALA B HB3    1 
ATOM   8350  N N      . TYR B 1 71  ? -18.939 -7.186  -15.926 1.00 17.85  ? 71  TYR B N      1 
ATOM   8351  C CA     . TYR B 1 71  ? -20.210 -6.484  -16.034 1.00 18.65  ? 71  TYR B CA     1 
ATOM   8352  C C      . TYR B 1 71  ? -20.675 -5.926  -14.693 1.00 19.34  ? 71  TYR B C      1 
ATOM   8353  O O      . TYR B 1 71  ? -21.353 -4.901  -14.649 1.00 18.58  ? 71  TYR B O      1 
ATOM   8354  C CB     . TYR B 1 71  ? -21.289 -7.418  -16.599 1.00 19.89  ? 71  TYR B CB     1 
ATOM   8355  C CG     . TYR B 1 71  ? -22.297 -6.714  -17.480 1.00 20.88  ? 71  TYR B CG     1 
ATOM   8356  C CD1    . TYR B 1 71  ? -21.907 -6.163  -18.701 1.00 21.55  ? 71  TYR B CD1    1 
ATOM   8357  C CD2    . TYR B 1 71  ? -23.630 -6.612  -17.113 1.00 21.14  ? 71  TYR B CD2    1 
ATOM   8358  C CE1    . TYR B 1 71  ? -22.805 -5.528  -19.521 1.00 24.62  ? 71  TYR B CE1    1 
ATOM   8359  C CE2    . TYR B 1 71  ? -24.548 -5.968  -17.937 1.00 23.01  ? 71  TYR B CE2    1 
ATOM   8360  C CZ     . TYR B 1 71  ? -24.123 -5.424  -19.138 1.00 27.03  ? 71  TYR B CZ     1 
ATOM   8361  O OH     . TYR B 1 71  ? -25.001 -4.779  -19.970 1.00 28.02  ? 71  TYR B OH     1 
ATOM   8362  H H      . TYR B 1 71  ? -18.999 -8.033  -16.064 1.00 21.42  ? 71  TYR B H      1 
ATOM   8363  H HA     . TYR B 1 71  ? -20.105 -5.739  -16.646 1.00 22.38  ? 71  TYR B HA     1 
ATOM   8364  H HB2    . TYR B 1 71  ? -20.858 -8.106  -17.128 1.00 23.87  ? 71  TYR B HB2    1 
ATOM   8365  H HB3    . TYR B 1 71  ? -21.771 -7.823  -15.861 1.00 23.87  ? 71  TYR B HB3    1 
ATOM   8366  H HD1    . TYR B 1 71  ? -21.017 -6.226  -18.964 1.00 25.86  ? 71  TYR B HD1    1 
ATOM   8367  H HD2    . TYR B 1 71  ? -23.913 -6.974  -16.305 1.00 25.37  ? 71  TYR B HD2    1 
ATOM   8368  H HE1    . TYR B 1 71  ? -22.523 -5.161  -20.327 1.00 29.54  ? 71  TYR B HE1    1 
ATOM   8369  H HE2    . TYR B 1 71  ? -25.439 -5.898  -17.680 1.00 27.61  ? 71  TYR B HE2    1 
ATOM   8370  H HH     . TYR B 1 71  ? -25.691 -4.566  -19.544 1.00 33.62  ? 71  TYR B HH     1 
ATOM   8371  N N      . ALA B 1 72  ? -20.303 -6.617  -13.618 1.00 18.27  ? 72  ALA B N      1 
ATOM   8372  C CA     . ALA B 1 72  ? -20.661 -6.249  -12.255 1.00 23.15  ? 72  ALA B CA     1 
ATOM   8373  C C      . ALA B 1 72  ? -19.457 -6.489  -11.362 1.00 16.49  ? 72  ALA B C      1 
ATOM   8374  O O      . ALA B 1 72  ? -18.680 -7.406  -11.604 1.00 19.83  ? 72  ALA B O      1 
ATOM   8375  C CB     . ALA B 1 72  ? -21.855 -7.070  -11.773 1.00 22.50  ? 72  ALA B CB     1 
ATOM   8376  H H      . ALA B 1 72  ? -19.825 -7.331  -13.657 1.00 21.92  ? 72  ALA B H      1 
ATOM   8377  H HA     . ALA B 1 72  ? -20.893 -5.308  -12.215 1.00 27.78  ? 72  ALA B HA     1 
ATOM   8378  H HB1    . ALA B 1 72  ? -22.073 -6.807  -10.865 1.00 27.00  ? 72  ALA B HB1    1 
ATOM   8379  H HB2    . ALA B 1 72  ? -22.610 -6.901  -12.357 1.00 27.00  ? 72  ALA B HB2    1 
ATOM   8380  H HB3    . ALA B 1 72  ? -21.621 -8.011  -11.798 1.00 27.00  ? 72  ALA B HB3    1 
ATOM   8381  N N      . GLY B 1 73  ? -19.294 -5.656  -10.336 1.00 16.72  ? 73  GLY B N      1 
ATOM   8382  C CA     . GLY B 1 73  ? -18.242 -5.847  -9.356  1.00 18.22  ? 73  GLY B CA     1 
ATOM   8383  C C      . GLY B 1 73  ? -16.826 -5.537  -9.819  1.00 18.22  ? 73  GLY B C      1 
ATOM   8384  O O      . GLY B 1 73  ? -15.858 -5.994  -9.213  1.00 15.68  ? 73  GLY B O      1 
ATOM   8385  H H      . GLY B 1 73  ? -19.788 -4.967  -10.189 1.00 20.07  ? 73  GLY B H      1 
ATOM   8386  H HA2    . GLY B 1 73  ? -18.429 -5.286  -8.587  1.00 21.87  ? 73  GLY B HA2    1 
ATOM   8387  H HA3    . GLY B 1 73  ? -18.259 -6.770  -9.059  1.00 21.87  ? 73  GLY B HA3    1 
ATOM   8388  N N      . SER B 1 74  ? -16.686 -4.758  -10.882 1.00 17.96  ? 74  SER B N      1 
ATOM   8389  C CA     . SER B 1 74  ? -15.354 -4.414  -11.365 1.00 14.25  ? 74  SER B CA     1 
ATOM   8390  C C      . SER B 1 74  ? -14.552 -3.630  -10.329 1.00 16.13  ? 74  SER B C      1 
ATOM   8391  O O      . SER B 1 74  ? -15.068 -2.694  -9.724  1.00 15.76  ? 74  SER B O      1 
ATOM   8392  C CB     . SER B 1 74  ? -15.432 -3.582  -12.636 1.00 17.09  ? 74  SER B CB     1 
ATOM   8393  O OG     . SER B 1 74  ? -14.155 -3.043  -12.908 1.00 17.91  ? 74  SER B OG     1 
ATOM   8394  H H      . SER B 1 74  ? -17.333 -4.420  -11.336 1.00 21.55  ? 74  SER B H      1 
ATOM   8395  H HA     . SER B 1 74  ? -14.870 -5.230  -11.568 1.00 17.10  ? 74  SER B HA     1 
ATOM   8396  H HB2    . SER B 1 74  ? -15.707 -4.147  -13.375 1.00 20.50  ? 74  SER B HB2    1 
ATOM   8397  H HB3    . SER B 1 74  ? -16.066 -2.859  -12.509 1.00 20.50  ? 74  SER B HB3    1 
ATOM   8398  H HG     . SER B 1 74  ? -14.182 -2.580  -13.608 1.00 21.49  ? 74  SER B HG     1 
ATOM   8399  N N      . GLU B 1 75  ? -13.285 -3.998  -10.163 1.00 17.42  ? 75  GLU B N      1 
ATOM   8400  C CA     . GLU B 1 75  ? -12.370 -3.254  -9.306  1.00 17.69  ? 75  GLU B CA     1 
ATOM   8401  C C      . GLU B 1 75  ? -12.308 -1.787  -9.705  1.00 18.16  ? 75  GLU B C      1 
ATOM   8402  O O      . GLU B 1 75  ? -12.117 -0.918  -8.845  1.00 16.90  ? 75  GLU B O      1 
ATOM   8403  C CB     . GLU B 1 75  ? -10.966 -3.855  -9.359  1.00 21.12  ? 75  GLU B CB     1 
ATOM   8404  C CG     . GLU B 1 75  ? -10.810 -5.106  -8.537  1.00 27.16  ? 75  GLU B CG     1 
ATOM   8405  C CD     . GLU B 1 75  ? -10.875 -4.817  -7.045  1.00 33.67  ? 75  GLU B CD     1 
ATOM   8406  O OE1    . GLU B 1 75  ? -11.987 -4.871  -6.471  1.00 24.82  ? 75  GLU B OE1    1 
ATOM   8407  O OE2    . GLU B 1 75  ? -9.816  -4.512  -6.456  1.00 32.97  ? 75  GLU B OE2    1 
ATOM   8408  H H      . GLU B 1 75  ? -12.928 -4.683  -10.541 1.00 20.90  ? 75  GLU B H      1 
ATOM   8409  H HA     . GLU B 1 75  ? -12.687 -3.301  -8.391  1.00 21.23  ? 75  GLU B HA     1 
ATOM   8410  H HB2    . GLU B 1 75  ? -10.755 -4.077  -10.280 1.00 25.34  ? 75  GLU B HB2    1 
ATOM   8411  H HB3    . GLU B 1 75  ? -10.333 -3.200  -9.026  1.00 25.34  ? 75  GLU B HB3    1 
ATOM   8412  H HG2    . GLU B 1 75  ? -11.524 -5.724  -8.758  1.00 32.60  ? 75  GLU B HG2    1 
ATOM   8413  H HG3    . GLU B 1 75  ? -9.949  -5.508  -8.730  1.00 32.60  ? 75  GLU B HG3    1 
ATOM   8414  N N      . ASN B 1 76  ? -12.446 -1.513  -11.008 1.00 14.39  ? 76  ASN B N      1 
ATOM   8415  C CA     . ASN B 1 76  ? -12.345 -0.149  -11.510 1.00 15.15  ? 76  ASN B CA     1 
ATOM   8416  C C      . ASN B 1 76  ? -13.543 0.688   -11.069 1.00 18.44  ? 76  ASN B C      1 
ATOM   8417  O O      . ASN B 1 76  ? -13.403 1.873   -10.778 1.00 14.66  ? 76  ASN B O      1 
ATOM   8418  C CB     . ASN B 1 76  ? -12.240 -0.114  -13.038 1.00 14.93  ? 76  ASN B CB     1 
ATOM   8419  C CG     . ASN B 1 76  ? -11.192 -1.059  -13.587 1.00 17.54  ? 76  ASN B CG     1 
ATOM   8420  O OD1    . ASN B 1 76  ? -11.475 -1.842  -14.492 1.00 18.81  ? 76  ASN B OD1    1 
ATOM   8421  N ND2    . ASN B 1 76  ? -9.977  -0.975  -13.068 1.00 16.34  ? 76  ASN B ND2    1 
ATOM   8422  H H      . ASN B 1 76  ? -12.598 -2.102  -11.616 1.00 17.27  ? 76  ASN B H      1 
ATOM   8423  H HA     . ASN B 1 76  ? -11.544 0.261   -11.147 1.00 18.18  ? 76  ASN B HA     1 
ATOM   8424  H HB2    . ASN B 1 76  ? -13.097 -0.365  -13.418 1.00 17.92  ? 76  ASN B HB2    1 
ATOM   8425  H HB3    . ASN B 1 76  ? -12.006 0.785   -13.315 1.00 17.92  ? 76  ASN B HB3    1 
ATOM   8426  H HD21   . ASN B 1 76  ? -9.352  -1.494  -13.351 1.00 19.61  ? 76  ASN B HD21   1 
ATOM   8427  H HD22   . ASN B 1 76  ? -9.813  -0.402  -12.448 1.00 19.61  ? 76  ASN B HD22   1 
ATOM   8428  N N      . PHE B 1 77  ? -14.725 0.073   -11.039 1.00 17.18  ? 77  PHE B N      1 
ATOM   8429  C CA     . PHE B 1 77  ? -15.911 0.756   -10.545 1.00 19.87  ? 77  PHE B CA     1 
ATOM   8430  C C      . PHE B 1 77  ? -15.716 1.135   -9.080  1.00 16.85  ? 77  PHE B C      1 
ATOM   8431  O O      . PHE B 1 77  ? -16.008 2.257   -8.667  1.00 15.11  ? 77  PHE B O      1 
ATOM   8432  C CB     . PHE B 1 77  ? -17.169 -0.117  -10.693 1.00 19.36  ? 77  PHE B CB     1 
ATOM   8433  C CG     . PHE B 1 77  ? -18.356 0.439   -9.964  1.00 19.06  ? 77  PHE B CG     1 
ATOM   8434  C CD1    . PHE B 1 77  ? -19.170 1.376   -10.563 1.00 19.93  ? 77  PHE B CD1    1 
ATOM   8435  C CD2    . PHE B 1 77  ? -18.624 0.060   -8.659  1.00 23.77  ? 77  PHE B CD2    1 
ATOM   8436  C CE1    . PHE B 1 77  ? -20.248 1.913   -9.883  1.00 26.76  ? 77  PHE B CE1    1 
ATOM   8437  C CE2    . PHE B 1 77  ? -19.700 0.590   -7.977  1.00 27.35  ? 77  PHE B CE2    1 
ATOM   8438  C CZ     . PHE B 1 77  ? -20.513 1.518   -8.590  1.00 24.15  ? 77  PHE B CZ     1 
ATOM   8439  H H      . PHE B 1 77  ? -14.863 -0.735  -11.298 1.00 20.61  ? 77  PHE B H      1 
ATOM   8440  H HA     . PHE B 1 77  ? -16.046 1.571   -11.054 1.00 23.85  ? 77  PHE B HA     1 
ATOM   8441  H HB2    . PHE B 1 77  ? -17.399 -0.182  -11.633 1.00 23.23  ? 77  PHE B HB2    1 
ATOM   8442  H HB3    . PHE B 1 77  ? -16.985 -0.999  -10.335 1.00 23.23  ? 77  PHE B HB3    1 
ATOM   8443  H HD1    . PHE B 1 77  ? -18.995 1.647   -11.435 1.00 23.91  ? 77  PHE B HD1    1 
ATOM   8444  H HD2    . PHE B 1 77  ? -18.077 -0.565  -8.240  1.00 28.53  ? 77  PHE B HD2    1 
ATOM   8445  H HE1    . PHE B 1 77  ? -20.797 2.537   -10.300 1.00 32.11  ? 77  PHE B HE1    1 
ATOM   8446  H HE2    . PHE B 1 77  ? -19.876 0.321   -7.104  1.00 32.82  ? 77  PHE B HE2    1 
ATOM   8447  H HZ     . PHE B 1 77  ? -21.241 1.874   -8.134  1.00 28.98  ? 77  PHE B HZ     1 
ATOM   8448  N N      . PHE B 1 78  ? -15.227 0.191   -8.287  1.00 19.59  ? 78  PHE B N      1 
ATOM   8449  C CA     . PHE B 1 78  ? -15.053 0.446   -6.871  1.00 18.50  ? 78  PHE B CA     1 
ATOM   8450  C C      . PHE B 1 78  ? -14.023 1.556   -6.648  1.00 19.42  ? 78  PHE B C      1 
ATOM   8451  O O      . PHE B 1 78  ? -14.208 2.385   -5.760  1.00 17.08  ? 78  PHE B O      1 
ATOM   8452  C CB     . PHE B 1 78  ? -14.653 -0.837  -6.135  1.00 18.21  ? 78  PHE B CB     1 
ATOM   8453  C CG     . PHE B 1 78  ? -15.766 -1.856  -6.057  1.00 22.03  ? 78  PHE B CG     1 
ATOM   8454  C CD1    . PHE B 1 78  ? -17.035 -1.485  -5.641  1.00 25.71  ? 78  PHE B CD1    1 
ATOM   8455  C CD2    . PHE B 1 78  ? -15.548 -3.174  -6.425  1.00 21.32  ? 78  PHE B CD2    1 
ATOM   8456  C CE1    . PHE B 1 78  ? -18.065 -2.416  -5.578  1.00 29.06  ? 78  PHE B CE1    1 
ATOM   8457  C CE2    . PHE B 1 78  ? -16.576 -4.113  -6.363  1.00 21.32  ? 78  PHE B CE2    1 
ATOM   8458  C CZ     . PHE B 1 78  ? -17.830 -3.731  -5.950  1.00 22.82  ? 78  PHE B CZ     1 
ATOM   8459  H H      . PHE B 1 78  ? -14.992 -0.596  -8.543  1.00 23.51  ? 78  PHE B H      1 
ATOM   8460  H HA     . PHE B 1 78  ? -15.895 0.757   -6.504  1.00 22.21  ? 78  PHE B HA     1 
ATOM   8461  H HB2    . PHE B 1 78  ? -13.907 -1.246  -6.600  1.00 21.86  ? 78  PHE B HB2    1 
ATOM   8462  H HB3    . PHE B 1 78  ? -14.392 -0.611  -5.229  1.00 21.86  ? 78  PHE B HB3    1 
ATOM   8463  H HD1    . PHE B 1 78  ? -17.198 -0.603  -5.396  1.00 30.85  ? 78  PHE B HD1    1 
ATOM   8464  H HD2    . PHE B 1 78  ? -14.703 -3.437  -6.710  1.00 25.58  ? 78  PHE B HD2    1 
ATOM   8465  H HE1    . PHE B 1 78  ? -18.912 -2.156  -5.295  1.00 34.87  ? 78  PHE B HE1    1 
ATOM   8466  H HE2    . PHE B 1 78  ? -16.416 -4.995  -6.611  1.00 25.59  ? 78  PHE B HE2    1 
ATOM   8467  H HZ     . PHE B 1 78  ? -18.516 -4.357  -5.905  1.00 27.39  ? 78  PHE B HZ     1 
ATOM   8468  N N      . HIS B 1 79  ? -12.957 1.587   -7.451  1.00 16.17  ? 79  HIS B N      1 
ATOM   8469  C CA     . HIS B 1 79  ? -11.951 2.651   -7.339  1.00 18.97  ? 79  HIS B CA     1 
ATOM   8470  C C      . HIS B 1 79  ? -12.585 4.008   -7.655  1.00 17.38  ? 79  HIS B C      1 
ATOM   8471  O O      . HIS B 1 79  ? -12.391 4.975   -6.928  1.00 17.65  ? 79  HIS B O      1 
ATOM   8472  C CB     . HIS B 1 79  ? -10.753 2.413   -8.276  1.00 20.11  ? 79  HIS B CB     1 
ATOM   8473  C CG     . HIS B 1 79  ? -9.921  1.214   -7.919  1.00 32.29  ? 79  HIS B CG     1 
ATOM   8474  N ND1    . HIS B 1 79  ? -9.142  0.549   -8.845  1.00 33.57  ? 79  HIS B ND1    1 
ATOM   8475  C CD2    . HIS B 1 79  ? -9.735  0.571   -6.741  1.00 41.05  ? 79  HIS B CD2    1 
ATOM   8476  C CE1    . HIS B 1 79  ? -8.521  -0.458  -8.254  1.00 37.12  ? 79  HIS B CE1    1 
ATOM   8477  N NE2    . HIS B 1 79  ? -8.861  -0.466  -6.977  1.00 35.16  ? 79  HIS B NE2    1 
ATOM   8478  H H      . HIS B 1 79  ? -12.792 1.008   -8.066  1.00 19.41  ? 79  HIS B H      1 
ATOM   8479  H HA     . HIS B 1 79  ? -11.620 2.679   -6.428  1.00 22.76  ? 79  HIS B HA     1 
ATOM   8480  H HB2    . HIS B 1 79  ? -11.085 2.284   -9.178  1.00 24.14  ? 79  HIS B HB2    1 
ATOM   8481  H HB3    . HIS B 1 79  ? -10.176 3.192   -8.247  1.00 24.14  ? 79  HIS B HB3    1 
ATOM   8482  H HD1    . HIS B 1 79  ? -9.076  0.754   -9.678  1.00 40.28  ? 79  HIS B HD1    1 
ATOM   8483  H HD2    . HIS B 1 79  ? -10.128 0.787   -5.926  1.00 49.26  ? 79  HIS B HD2    1 
ATOM   8484  H HE1    . HIS B 1 79  ? -7.940  -1.056  -8.666  1.00 44.54  ? 79  HIS B HE1    1 
ATOM   8485  N N      . LEU B 1 80  ? -13.345 4.073   -8.743  1.00 16.29  ? 80  LEU B N      1 
ATOM   8486  C CA     . LEU B 1 80  ? -14.012 5.316   -9.129  1.00 17.63  ? 80  LEU B CA     1 
ATOM   8487  C C      . LEU B 1 80  ? -14.980 5.777   -8.036  1.00 18.93  ? 80  LEU B C      1 
ATOM   8488  O O      . LEU B 1 80  ? -14.983 6.950   -7.630  1.00 16.11  ? 80  LEU B O      1 
ATOM   8489  C CB     . LEU B 1 80  ? -14.757 5.130   -10.452 1.00 17.62  ? 80  LEU B CB     1 
ATOM   8490  C CG     . LEU B 1 80  ? -15.602 6.322   -10.920 1.00 15.98  ? 80  LEU B CG     1 
ATOM   8491  C CD1    . LEU B 1 80  ? -14.715 7.563   -11.135 1.00 17.46  ? 80  LEU B CD1    1 
ATOM   8492  C CD2    . LEU B 1 80  ? -16.373 5.996   -12.197 1.00 20.03  ? 80  LEU B CD2    1 
ATOM   8493  H H      . LEU B 1 80  ? -13.492 3.414   -9.275  1.00 19.55  ? 80  LEU B H      1 
ATOM   8494  H HA     . LEU B 1 80  ? -13.346 6.010   -9.250  1.00 21.15  ? 80  LEU B HA     1 
ATOM   8495  H HB2    . LEU B 1 80  ? -14.105 4.947   -11.146 1.00 21.15  ? 80  LEU B HB2    1 
ATOM   8496  H HB3    . LEU B 1 80  ? -15.353 4.370   -10.362 1.00 21.15  ? 80  LEU B HB3    1 
ATOM   8497  H HG     . LEU B 1 80  ? -16.253 6.538   -10.235 1.00 19.18  ? 80  LEU B HG     1 
ATOM   8498  H HD11   . LEU B 1 80  ? -15.258 8.278   -11.503 1.00 20.95  ? 80  LEU B HD11   1 
ATOM   8499  H HD12   . LEU B 1 80  ? -14.341 7.836   -10.283 1.00 20.95  ? 80  LEU B HD12   1 
ATOM   8500  H HD13   . LEU B 1 80  ? -14.002 7.338   -11.753 1.00 20.95  ? 80  LEU B HD13   1 
ATOM   8501  H HD21   . LEU B 1 80  ? -16.893 6.772   -12.458 1.00 24.03  ? 80  LEU B HD21   1 
ATOM   8502  H HD22   . LEU B 1 80  ? -15.741 5.769   -12.897 1.00 24.03  ? 80  LEU B HD22   1 
ATOM   8503  H HD23   . LEU B 1 80  ? -16.963 5.245   -12.026 1.00 24.03  ? 80  LEU B HD23   1 
ATOM   8504  N N      . GLU B 1 81  ? -15.784 4.839   -7.551  1.00 18.16  ? 81  GLU B N      1 
ATOM   8505  C CA     . GLU B 1 81  ? -16.778 5.138   -6.530  1.00 18.23  ? 81  GLU B CA     1 
ATOM   8506  C C      . GLU B 1 81  ? -16.122 5.689   -5.267  1.00 14.19  ? 81  GLU B C      1 
ATOM   8507  O O      . GLU B 1 81  ? -16.546 6.718   -4.732  1.00 17.52  ? 81  GLU B O      1 
ATOM   8508  C CB     . GLU B 1 81  ? -17.591 3.882   -6.210  1.00 21.01  ? 81  GLU B CB     1 
ATOM   8509  C CG     . GLU B 1 81  ? -18.588 4.057   -5.091  1.00 26.86  ? 81  GLU B CG     1 
ATOM   8510  C CD     . GLU B 1 81  ? -19.393 2.794   -4.837  1.00 35.10  ? 81  GLU B CD     1 
ATOM   8511  O OE1    . GLU B 1 81  ? -18.779 1.779   -4.449  1.00 23.69  ? 81  GLU B OE1    1 
ATOM   8512  O OE2    . GLU B 1 81  ? -20.630 2.814   -5.032  1.00 30.00  ? 81  GLU B OE2    1 
ATOM   8513  H H      . GLU B 1 81  ? -15.773 4.016   -7.799  1.00 21.79  ? 81  GLU B H      1 
ATOM   8514  H HA     . GLU B 1 81  ? -17.382 5.814   -6.870  1.00 21.88  ? 81  GLU B HA     1 
ATOM   8515  H HB2    . GLU B 1 81  ? -18.082 3.619   -7.004  1.00 25.21  ? 81  GLU B HB2    1 
ATOM   8516  H HB3    . GLU B 1 81  ? -16.980 3.173   -5.953  1.00 25.21  ? 81  GLU B HB3    1 
ATOM   8517  H HG2    . GLU B 1 81  ? -18.119 4.278   -4.272  1.00 32.23  ? 81  GLU B HG2    1 
ATOM   8518  H HG3    . GLU B 1 81  ? -19.206 4.768   -5.324  1.00 32.23  ? 81  GLU B HG3    1 
ATOM   8519  N N      . ARG B 1 82  ? -15.071 5.040   -4.786  1.00 18.12  ? 82  ARG B N      1 
ATOM   8520  C CA     . ARG B 1 82  ? -14.468 5.492   -3.539  1.00 20.52  ? 82  ARG B CA     1 
ATOM   8521  C C      . ARG B 1 82  ? -13.725 6.811   -3.758  1.00 21.70  ? 82  ARG B C      1 
ATOM   8522  O O      . ARG B 1 82  ? -13.704 7.667   -2.878  1.00 18.52  ? 82  ARG B O      1 
ATOM   8523  C CB     . ARG B 1 82  ? -13.540 4.433   -2.950  1.00 22.79  ? 82  ARG B CB     1 
ATOM   8524  C CG     . ARG B 1 82  ? -12.256 4.192   -3.678  1.00 36.83  ? 82  ARG B CG     1 
ATOM   8525  C CD     . ARG B 1 82  ? -11.452 3.109   -2.956  1.00 55.98  ? 82  ARG B CD     1 
ATOM   8526  N NE     . ARG B 1 82  ? -10.291 2.665   -3.722  1.00 63.34  ? 82  ARG B NE     1 
ATOM   8527  C CZ     . ARG B 1 82  ? -9.479  1.681   -3.349  1.00 76.40  ? 82  ARG B CZ     1 
ATOM   8528  N NH1    . ARG B 1 82  ? -9.698  1.028   -2.213  1.00 85.56  ? 82  ARG B NH1    1 
ATOM   8529  N NH2    . ARG B 1 82  ? -8.446  1.350   -4.112  1.00 72.59  ? 82  ARG B NH2    1 
ATOM   8530  H H      . ARG B 1 82  ? -14.697 4.356   -5.148  1.00 21.75  ? 82  ARG B H      1 
ATOM   8531  H HA     . ARG B 1 82  ? -15.172 5.654   -2.892  1.00 24.62  ? 82  ARG B HA     1 
ATOM   8532  H HB2    . ARG B 1 82  ? -13.312 4.699   -2.045  1.00 27.35  ? 82  ARG B HB2    1 
ATOM   8533  H HB3    . ARG B 1 82  ? -14.019 3.590   -2.925  1.00 27.35  ? 82  ARG B HB3    1 
ATOM   8534  H HG2    . ARG B 1 82  ? -12.444 3.888   -4.579  1.00 44.19  ? 82  ARG B HG2    1 
ATOM   8535  H HG3    . ARG B 1 82  ? -11.729 5.006   -3.694  1.00 44.19  ? 82  ARG B HG3    1 
ATOM   8536  H HD2    . ARG B 1 82  ? -11.136 3.461   -2.109  1.00 67.18  ? 82  ARG B HD2    1 
ATOM   8537  H HD3    . ARG B 1 82  ? -12.023 2.340   -2.804  1.00 67.18  ? 82  ARG B HD3    1 
ATOM   8538  H HE     . ARG B 1 82  ? -10.121 3.067   -4.463  1.00 76.01  ? 82  ARG B HE     1 
ATOM   8539  H HH11   . ARG B 1 82  ? -10.366 1.238   -1.714  1.00 102.68 ? 82  ARG B HH11   1 
ATOM   8540  H HH12   . ARG B 1 82  ? -9.170  0.392   -1.976  1.00 102.68 ? 82  ARG B HH12   1 
ATOM   8541  H HH21   . ARG B 1 82  ? -8.302  1.771   -4.848  1.00 87.11  ? 82  ARG B HH21   1 
ATOM   8542  H HH22   . ARG B 1 82  ? -7.921  0.713   -3.872  1.00 87.11  ? 82  ARG B HH22   1 
ATOM   8543  N N      . THR B 1 83  ? -13.150 6.990   -4.941  1.00 15.60  ? 83  THR B N      1 
ATOM   8544  C CA     . THR B 1 83  ? -12.478 8.250   -5.255  1.00 16.34  ? 83  THR B CA     1 
ATOM   8545  C C      . THR B 1 83  ? -13.458 9.430   -5.260  1.00 18.82  ? 83  THR B C      1 
ATOM   8546  O O      . THR B 1 83  ? -13.171 10.486  -4.688  1.00 19.55  ? 83  THR B O      1 
ATOM   8547  C CB     . THR B 1 83  ? -11.762 8.166   -6.611  1.00 19.92  ? 83  THR B CB     1 
ATOM   8548  O OG1    . THR B 1 83  ? -10.687 7.225   -6.513  1.00 19.50  ? 83  THR B OG1    1 
ATOM   8549  C CG2    . THR B 1 83  ? -11.198 9.521   -7.019  1.00 16.94  ? 83  THR B CG2    1 
ATOM   8550  H H      . THR B 1 83  ? -13.133 6.408   -5.573  1.00 18.73  ? 83  THR B H      1 
ATOM   8551  H HA     . THR B 1 83  ? -11.808 8.424   -4.576  1.00 19.61  ? 83  THR B HA     1 
ATOM   8552  H HB     . THR B 1 83  ? -12.388 7.874   -7.292  1.00 23.90  ? 83  THR B HB     1 
ATOM   8553  H HG1    . THR B 1 83  ? -10.986 6.467   -6.307  1.00 23.40  ? 83  THR B HG1    1 
ATOM   8554  H HG21   . THR B 1 83  ? -10.520 9.403   -7.702  1.00 20.33  ? 83  THR B HG21   1 
ATOM   8555  H HG22   . THR B 1 83  ? -11.904 10.085  -7.373  1.00 20.33  ? 83  THR B HG22   1 
ATOM   8556  H HG23   . THR B 1 83  ? -10.797 9.958   -6.251  1.00 20.33  ? 83  THR B HG23   1 
ATOM   8557  N N      . VAL B 1 84  ? -14.610 9.267   -5.898  1.00 15.32  ? 84  VAL B N      1 
ATOM   8558  C CA     . VAL B 1 84  ? -15.559 10.373  -5.978  1.00 18.87  ? 84  VAL B CA     1 
ATOM   8559  C C      . VAL B 1 84  ? -16.180 10.621  -4.604  1.00 20.53  ? 84  VAL B C      1 
ATOM   8560  O O      . VAL B 1 84  ? -16.375 11.772  -4.203  1.00 19.23  ? 84  VAL B O      1 
ATOM   8561  C CB     . VAL B 1 84  ? -16.643 10.114  -7.039  1.00 20.51  ? 84  VAL B CB     1 
ATOM   8562  C CG1    . VAL B 1 84  ? -17.707 11.217  -7.032  1.00 22.48  ? 84  VAL B CG1    1 
ATOM   8563  C CG2    . VAL B 1 84  ? -16.000 10.046  -8.402  1.00 16.05  ? 84  VAL B CG2    1 
ATOM   8564  H H      . VAL B 1 84  ? -14.864 8.543   -6.286  1.00 18.39  ? 84  VAL B H      1 
ATOM   8565  H HA     . VAL B 1 84  ? -15.082 11.177  -6.237  1.00 22.65  ? 84  VAL B HA     1 
ATOM   8566  H HB     . VAL B 1 84  ? -17.077 9.265   -6.860  1.00 24.61  ? 84  VAL B HB     1 
ATOM   8567  H HG11   . VAL B 1 84  ? -18.238 11.145  -7.841  1.00 26.98  ? 84  VAL B HG11   1 
ATOM   8568  H HG12   . VAL B 1 84  ? -18.275 11.107  -6.254  1.00 26.98  ? 84  VAL B HG12   1 
ATOM   8569  H HG13   . VAL B 1 84  ? -17.266 12.080  -7.003  1.00 26.98  ? 84  VAL B HG13   1 
ATOM   8570  H HG21   . VAL B 1 84  ? -16.687 9.906   -9.071  1.00 19.26  ? 84  VAL B HG21   1 
ATOM   8571  H HG22   . VAL B 1 84  ? -15.539 10.882  -8.573  1.00 19.26  ? 84  VAL B HG22   1 
ATOM   8572  H HG23   . VAL B 1 84  ? -15.367 9.312   -8.419  1.00 19.26  ? 84  VAL B HG23   1 
ATOM   8573  N N      . GLN B 1 85  ? -16.452 9.552   -3.860  1.00 20.26  ? 85  GLN B N      1 
ATOM   8574  C CA     . GLN B 1 85  ? -16.990 9.706   -2.508  1.00 20.15  ? 85  GLN B CA     1 
ATOM   8575  C C      . GLN B 1 85  ? -16.017 10.496  -1.636  1.00 21.62  ? 85  GLN B C      1 
ATOM   8576  O O      . GLN B 1 85  ? -16.432 11.406  -0.911  1.00 20.94  ? 85  GLN B O      1 
ATOM   8577  C CB     . GLN B 1 85  ? -17.299 8.345   -1.887  1.00 20.37  ? 85  GLN B CB     1 
ATOM   8578  C CG     . GLN B 1 85  ? -18.545 7.708   -2.490  1.00 27.53  ? 85  GLN B CG     1 
ATOM   8579  C CD     . GLN B 1 85  ? -18.797 6.281   -2.026  1.00 38.80  ? 85  GLN B CD     1 
ATOM   8580  O OE1    . GLN B 1 85  ? -17.887 5.590   -1.561  1.00 33.65  ? 85  GLN B OE1    1 
ATOM   8581  N NE2    . GLN B 1 85  ? -20.046 5.833   -2.155  1.00 29.29  ? 85  GLN B NE2    1 
ATOM   8582  H H      . GLN B 1 85  ? -16.337 8.737   -4.109  1.00 24.31  ? 85  GLN B H      1 
ATOM   8583  H HA     . GLN B 1 85  ? -17.820 10.206  -2.556  1.00 24.18  ? 85  GLN B HA     1 
ATOM   8584  H HB2    . GLN B 1 85  ? -16.549 7.749   -2.041  1.00 24.44  ? 85  GLN B HB2    1 
ATOM   8585  H HB3    . GLN B 1 85  ? -17.447 8.456   -0.935  1.00 24.44  ? 85  GLN B HB3    1 
ATOM   8586  H HG2    . GLN B 1 85  ? -19.317 8.239   -2.238  1.00 33.04  ? 85  GLN B HG2    1 
ATOM   8587  H HG3    . GLN B 1 85  ? -18.458 7.697   -3.455  1.00 33.04  ? 85  GLN B HG3    1 
ATOM   8588  H HE21   . GLN B 1 85  ? -20.654 6.344   -2.485  1.00 35.15  ? 85  GLN B HE21   1 
ATOM   8589  H HE22   . GLN B 1 85  ? -20.244 5.033   -1.908  1.00 35.15  ? 85  GLN B HE22   1 
ATOM   8590  N N      . GLU B 1 86  ? -14.729 10.176  -1.734  1.00 18.24  ? 86  GLU B N      1 
ATOM   8591  C CA     . GLU B 1 86  ? -13.691 10.882  -0.971  1.00 20.16  ? 86  GLU B CA     1 
ATOM   8592  C C      . GLU B 1 86  ? -13.527 12.343  -1.390  1.00 24.00  ? 86  GLU B C      1 
ATOM   8593  O O      . GLU B 1 86  ? -13.494 13.240  -0.546  1.00 20.33  ? 86  GLU B O      1 
ATOM   8594  C CB     . GLU B 1 86  ? -12.344 10.165  -1.117  1.00 21.18  ? 86  GLU B CB     1 
ATOM   8595  C CG     . GLU B 1 86  ? -11.170 10.865  -0.430  1.00 27.29  ? 86  GLU B CG     1 
ATOM   8596  C CD     . GLU B 1 86  ? -9.826  10.212  -0.737  1.00 36.13  ? 86  GLU B CD     1 
ATOM   8597  O OE1    . GLU B 1 86  ? -9.812  9.022   -1.120  1.00 33.56  ? 86  GLU B OE1    1 
ATOM   8598  O OE2    . GLU B 1 86  ? -8.783  10.894  -0.599  1.00 34.71  ? 86  GLU B OE2    1 
ATOM   8599  H H      . GLU B 1 86  ? -14.424 9.550   -2.238  1.00 21.89  ? 86  GLU B H      1 
ATOM   8600  H HA     . GLU B 1 86  ? -13.933 10.869  -0.032  1.00 24.20  ? 86  GLU B HA     1 
ATOM   8601  H HB2    . GLU B 1 86  ? -12.423 9.278   -0.733  1.00 25.42  ? 86  GLU B HB2    1 
ATOM   8602  H HB3    . GLU B 1 86  ? -12.132 10.094  -2.061  1.00 25.42  ? 86  GLU B HB3    1 
ATOM   8603  H HG2    . GLU B 1 86  ? -11.117 11.785  -0.729  1.00 32.74  ? 86  GLU B HG2    1 
ATOM   8604  H HG3    . GLU B 1 86  ? -11.304 10.836  0.530   1.00 32.74  ? 86  GLU B HG3    1 
ATOM   8605  N N      . LEU B 1 87  ? -13.419 12.588  -2.689  1.00 18.70  ? 87  LEU B N      1 
ATOM   8606  C CA     . LEU B 1 87  ? -13.049 13.917  -3.162  1.00 21.57  ? 87  LEU B CA     1 
ATOM   8607  C C      . LEU B 1 87  ? -14.230 14.870  -3.328  1.00 21.52  ? 87  LEU B C      1 
ATOM   8608  O O      . LEU B 1 87  ? -14.074 16.072  -3.106  1.00 20.34  ? 87  LEU B O      1 
ATOM   8609  C CB     . LEU B 1 87  ? -12.293 13.807  -4.487  1.00 20.06  ? 87  LEU B CB     1 
ATOM   8610  C CG     . LEU B 1 87  ? -10.943 13.081  -4.390  1.00 19.89  ? 87  LEU B CG     1 
ATOM   8611  C CD1    . LEU B 1 87  ? -10.264 13.040  -5.752  1.00 24.09  ? 87  LEU B CD1    1 
ATOM   8612  C CD2    . LEU B 1 87  ? -10.019 13.719  -3.379  1.00 24.00  ? 87  LEU B CD2    1 
ATOM   8613  H H      . LEU B 1 87  ? -13.553 12.010  -3.312  1.00 22.44  ? 87  LEU B H      1 
ATOM   8614  H HA     . LEU B 1 87  ? -12.450 14.318  -2.515  1.00 25.89  ? 87  LEU B HA     1 
ATOM   8615  H HB2    . LEU B 1 87  ? -12.844 13.320  -5.119  1.00 24.07  ? 87  LEU B HB2    1 
ATOM   8616  H HB3    . LEU B 1 87  ? -12.123 14.701  -4.822  1.00 24.07  ? 87  LEU B HB3    1 
ATOM   8617  H HG     . LEU B 1 87  ? -11.101 12.166  -4.110  1.00 23.87  ? 87  LEU B HG     1 
ATOM   8618  H HD11   . LEU B 1 87  ? -9.424  12.562  -5.672  1.00 28.91  ? 87  LEU B HD11   1 
ATOM   8619  H HD12   . LEU B 1 87  ? -10.846 12.584  -6.380  1.00 28.91  ? 87  LEU B HD12   1 
ATOM   8620  H HD13   . LEU B 1 87  ? -10.101 13.948  -6.050  1.00 28.91  ? 87  LEU B HD13   1 
ATOM   8621  H HD21   . LEU B 1 87  ? -9.127  13.355  -3.493  1.00 28.79  ? 87  LEU B HD21   1 
ATOM   8622  H HD22   . LEU B 1 87  ? -10.007 14.678  -3.525  1.00 28.79  ? 87  LEU B HD22   1 
ATOM   8623  H HD23   . LEU B 1 87  ? -10.343 13.524  -2.486  1.00 28.79  ? 87  LEU B HD23   1 
ATOM   8624  N N      . PHE B 1 88  ? -15.398 14.350  -3.707  1.00 19.01  ? 88  PHE B N      1 
ATOM   8625  C CA     . PHE B 1 88  ? -16.585 15.193  -3.884  1.00 20.37  ? 88  PHE B CA     1 
ATOM   8626  C C      . PHE B 1 88  ? -17.515 15.125  -2.667  1.00 21.45  ? 88  PHE B C      1 
ATOM   8627  O O      . PHE B 1 88  ? -18.273 16.058  -2.406  1.00 23.26  ? 88  PHE B O      1 
ATOM   8628  C CB     . PHE B 1 88  ? -17.377 14.791  -5.137  1.00 20.48  ? 88  PHE B CB     1 
ATOM   8629  C CG     . PHE B 1 88  ? -16.778 15.267  -6.436  1.00 22.64  ? 88  PHE B CG     1 
ATOM   8630  C CD1    . PHE B 1 88  ? -15.483 15.754  -6.506  1.00 21.21  ? 88  PHE B CD1    1 
ATOM   8631  C CD2    . PHE B 1 88  ? -17.533 15.221  -7.598  1.00 23.98  ? 88  PHE B CD2    1 
ATOM   8632  C CE1    . PHE B 1 88  ? -14.948 16.182  -7.717  1.00 22.73  ? 88  PHE B CE1    1 
ATOM   8633  C CE2    . PHE B 1 88  ? -17.005 15.649  -8.813  1.00 25.29  ? 88  PHE B CE2    1 
ATOM   8634  C CZ     . PHE B 1 88  ? -15.711 16.132  -8.869  1.00 23.56  ? 88  PHE B CZ     1 
ATOM   8635  H H      . PHE B 1 88  ? -15.531 13.516  -3.868  1.00 22.81  ? 88  PHE B H      1 
ATOM   8636  H HA     . PHE B 1 88  ? -16.315 16.118  -3.989  1.00 24.44  ? 88  PHE B HA     1 
ATOM   8637  H HB2    . PHE B 1 88  ? -17.432 13.824  -5.176  1.00 24.58  ? 88  PHE B HB2    1 
ATOM   8638  H HB3    . PHE B 1 88  ? -18.269 15.165  -5.072  1.00 24.58  ? 88  PHE B HB3    1 
ATOM   8639  H HD1    . PHE B 1 88  ? -14.961 15.791  -5.737  1.00 25.45  ? 88  PHE B HD1    1 
ATOM   8640  H HD2    . PHE B 1 88  ? -18.404 14.896  -7.566  1.00 28.78  ? 88  PHE B HD2    1 
ATOM   8641  H HE1    . PHE B 1 88  ? -14.077 16.507  -7.751  1.00 27.27  ? 88  PHE B HE1    1 
ATOM   8642  H HE2    . PHE B 1 88  ? -17.523 15.613  -9.585  1.00 30.34  ? 88  PHE B HE2    1 
ATOM   8643  H HZ     . PHE B 1 88  ? -15.355 16.420  -9.678  1.00 28.28  ? 88  PHE B HZ     1 
ATOM   8644  N N      . GLY B 1 89  ? -17.491 14.006  -1.951  1.00 22.02  ? 89  GLY B N      1 
ATOM   8645  C CA     . GLY B 1 89  ? -18.261 13.876  -0.727  1.00 23.38  ? 89  GLY B CA     1 
ATOM   8646  C C      . GLY B 1 89  ? -19.697 13.398  -0.875  1.00 31.91  ? 89  GLY B C      1 
ATOM   8647  O O      . GLY B 1 89  ? -20.409 13.277  0.123   1.00 33.47  ? 89  GLY B O      1 
ATOM   8648  H H      . GLY B 1 89  ? -17.035 13.306  -2.156  1.00 26.42  ? 89  GLY B H      1 
ATOM   8649  H HA2    . GLY B 1 89  ? -17.807 13.260  -0.133  1.00 28.06  ? 89  GLY B HA2    1 
ATOM   8650  H HA3    . GLY B 1 89  ? -18.286 14.738  -0.284  1.00 28.06  ? 89  GLY B HA3    1 
ATOM   8651  N N      . PHE B 1 90  ? -20.140 13.116  -2.096  1.00 21.39  ? 90  PHE B N      1 
ATOM   8652  C CA     . PHE B 1 90  ? -21.509 12.655  -2.289  1.00 23.47  ? 90  PHE B CA     1 
ATOM   8653  C C      . PHE B 1 90  ? -21.653 11.195  -1.852  1.00 24.81  ? 90  PHE B C      1 
ATOM   8654  O O      . PHE B 1 90  ? -20.697 10.409  -1.892  1.00 23.21  ? 90  PHE B O      1 
ATOM   8655  C CB     . PHE B 1 90  ? -21.951 12.821  -3.751  1.00 24.48  ? 90  PHE B CB     1 
ATOM   8656  C CG     . PHE B 1 90  ? -22.042 14.256  -4.202  1.00 26.00  ? 90  PHE B CG     1 
ATOM   8657  C CD1    . PHE B 1 90  ? -23.024 15.101  -3.697  1.00 23.80  ? 90  PHE B CD1    1 
ATOM   8658  C CD2    . PHE B 1 90  ? -21.154 14.756  -5.135  1.00 21.18  ? 90  PHE B CD2    1 
ATOM   8659  C CE1    . PHE B 1 90  ? -23.102 16.421  -4.112  1.00 27.67  ? 90  PHE B CE1    1 
ATOM   8660  C CE2    . PHE B 1 90  ? -21.233 16.070  -5.559  1.00 24.51  ? 90  PHE B CE2    1 
ATOM   8661  C CZ     . PHE B 1 90  ? -22.208 16.902  -5.048  1.00 24.60  ? 90  PHE B CZ     1 
ATOM   8662  H H      . PHE B 1 90  ? -19.677 13.182  -2.818  1.00 25.66  ? 90  PHE B H      1 
ATOM   8663  H HA     . PHE B 1 90  ? -22.101 13.191  -1.740  1.00 28.17  ? 90  PHE B HA     1 
ATOM   8664  H HB2    . PHE B 1 90  ? -21.311 12.371  -4.324  1.00 29.38  ? 90  PHE B HB2    1 
ATOM   8665  H HB3    . PHE B 1 90  ? -22.828 12.420  -3.860  1.00 29.38  ? 90  PHE B HB3    1 
ATOM   8666  H HD1    . PHE B 1 90  ? -23.628 14.780  -3.067  1.00 28.57  ? 90  PHE B HD1    1 
ATOM   8667  H HD2    . PHE B 1 90  ? -20.495 14.201  -5.484  1.00 25.41  ? 90  PHE B HD2    1 
ATOM   8668  H HE1    . PHE B 1 90  ? -23.762 16.979  -3.769  1.00 33.20  ? 90  PHE B HE1    1 
ATOM   8669  H HE2    . PHE B 1 90  ? -20.627 16.394  -6.186  1.00 29.41  ? 90  PHE B HE2    1 
ATOM   8670  H HZ     . PHE B 1 90  ? -22.260 17.787  -5.330  1.00 29.52  ? 90  PHE B HZ     1 
ATOM   8671  N N      . LYS B 1 91  ? -22.862 10.833  -1.440  1.00 24.07  ? 91  LYS B N      1 
ATOM   8672  C CA     . LYS B 1 91  ? -23.122 9.493   -0.940  1.00 28.15  ? 91  LYS B CA     1 
ATOM   8673  C C      . LYS B 1 91  ? -23.117 8.448   -2.058  1.00 26.32  ? 91  LYS B C      1 
ATOM   8674  O O      . LYS B 1 91  ? -22.596 7.351   -1.874  1.00 23.75  ? 91  LYS B O      1 
ATOM   8675  C CB     . LYS B 1 91  ? -24.463 9.460   -0.199  1.00 28.65  ? 91  LYS B CB     1 
ATOM   8676  C CG     . LYS B 1 91  ? -24.714 8.170   0.544   1.00 37.96  ? 91  LYS B CG     1 
ATOM   8677  C CD     . LYS B 1 91  ? -26.028 8.207   1.316   1.00 40.64  ? 91  LYS B CD     1 
ATOM   8678  C CE     . LYS B 1 91  ? -26.226 6.924   2.120   1.00 47.81  ? 91  LYS B CE     1 
ATOM   8679  N NZ     . LYS B 1 91  ? -27.571 6.855   2.761   1.00 53.64  ? 91  LYS B NZ     1 
ATOM   8680  H H      . LYS B 1 91  ? -23.551 11.348  -1.440  1.00 28.88  ? 91  LYS B H      1 
ATOM   8681  H HA     . LYS B 1 91  ? -22.427 9.254   -0.307  1.00 33.77  ? 91  LYS B HA     1 
ATOM   8682  H HB2    . LYS B 1 91  ? -24.481 10.183  0.447   1.00 34.38  ? 91  LYS B HB2    1 
ATOM   8683  H HB3    . LYS B 1 91  ? -25.179 9.576   -0.843  1.00 34.38  ? 91  LYS B HB3    1 
ATOM   8684  H HG2    . LYS B 1 91  ? -24.756 7.438   -0.090  1.00 45.55  ? 91  LYS B HG2    1 
ATOM   8685  H HG3    . LYS B 1 91  ? -23.995 8.022   1.178   1.00 45.55  ? 91  LYS B HG3    1 
ATOM   8686  H HD2    . LYS B 1 91  ? -26.018 8.956   1.933   1.00 48.77  ? 91  LYS B HD2    1 
ATOM   8687  H HD3    . LYS B 1 91  ? -26.766 8.294   0.692   1.00 48.77  ? 91  LYS B HD3    1 
ATOM   8688  H HE2    . LYS B 1 91  ? -26.136 6.161   1.527   1.00 57.37  ? 91  LYS B HE2    1 
ATOM   8689  H HE3    . LYS B 1 91  ? -25.556 6.882   2.821   1.00 57.37  ? 91  LYS B HE3    1 
ATOM   8690  H HZ1    . LYS B 1 91  ? -27.662 7.517   3.349   1.00 64.36  ? 91  LYS B HZ1    1 
ATOM   8691  H HZ2    . LYS B 1 91  ? -28.206 6.929   2.142   1.00 64.36  ? 91  LYS B HZ2    1 
ATOM   8692  H HZ3    . LYS B 1 91  ? -27.667 6.078   3.184   1.00 64.36  ? 91  LYS B HZ3    1 
ATOM   8693  N N      . HIS B 1 92  ? -23.685 8.793   -3.213  1.00 22.54  ? 92  HIS B N      1 
ATOM   8694  C CA     . HIS B 1 92  ? -23.901 7.824   -4.281  1.00 22.91  ? 92  HIS B CA     1 
ATOM   8695  C C      . HIS B 1 92  ? -23.345 8.329   -5.605  1.00 24.99  ? 92  HIS B C      1 
ATOM   8696  O O      . HIS B 1 92  ? -23.368 9.530   -5.880  1.00 23.63  ? 92  HIS B O      1 
ATOM   8697  C CB     . HIS B 1 92  ? -25.393 7.516   -4.445  1.00 27.92  ? 92  HIS B CB     1 
ATOM   8698  C CG     . HIS B 1 92  ? -26.054 7.026   -3.195  1.00 32.04  ? 92  HIS B CG     1 
ATOM   8699  N ND1    . HIS B 1 92  ? -25.690 5.853   -2.569  1.00 32.44  ? 92  HIS B ND1    1 
ATOM   8700  C CD2    . HIS B 1 92  ? -27.060 7.551   -2.454  1.00 37.58  ? 92  HIS B CD2    1 
ATOM   8701  C CE1    . HIS B 1 92  ? -26.441 5.679   -1.495  1.00 35.37  ? 92  HIS B CE1    1 
ATOM   8702  N NE2    . HIS B 1 92  ? -27.279 6.696   -1.403  1.00 33.09  ? 92  HIS B NE2    1 
ATOM   8703  H H      . HIS B 1 92  ? -23.955 9.587   -3.402  1.00 27.05  ? 92  HIS B H      1 
ATOM   8704  H HA     . HIS B 1 92  ? -23.449 6.993   -4.071  1.00 27.49  ? 92  HIS B HA     1 
ATOM   8705  H HB2    . HIS B 1 92  ? -25.852 8.321   -4.730  1.00 33.50  ? 92  HIS B HB2    1 
ATOM   8706  H HB3    . HIS B 1 92  ? -25.486 6.827   -5.117  1.00 33.50  ? 92  HIS B HB3    1 
ATOM   8707  H HD1    . HIS B 1 92  ? -25.070 5.320   -2.834  1.00 38.92  ? 92  HIS B HD1    1 
ATOM   8708  H HD2    . HIS B 1 92  ? -27.514 8.345   -2.624  1.00 45.10  ? 92  HIS B HD2    1 
ATOM   8709  H HE1    . HIS B 1 92  ? -26.389 4.962   -0.905  1.00 42.44  ? 92  HIS B HE1    1 
ATOM   8710  H HE2    . HIS B 1 92  ? -27.868 6.803   -0.786  1.00 39.71  ? 92  HIS B HE2    1 
ATOM   8711  N N      . ILE B 1 93  ? -22.851 7.396   -6.409  1.00 21.17  ? 93  ILE B N      1 
ATOM   8712  C CA     . ILE B 1 93  ? -22.394 7.697   -7.761  1.00 22.20  ? 93  ILE B CA     1 
ATOM   8713  C C      . ILE B 1 93  ? -22.930 6.698   -8.785  1.00 23.04  ? 93  ILE B C      1 
ATOM   8714  O O      . ILE B 1 93  ? -22.978 5.493   -8.530  1.00 22.26  ? 93  ILE B O      1 
ATOM   8715  C CB     . ILE B 1 93  ? -20.864 7.700   -7.841  1.00 25.29  ? 93  ILE B CB     1 
ATOM   8716  C CG1    . ILE B 1 93  ? -20.421 8.124   -9.243  1.00 27.53  ? 93  ILE B CG1    1 
ATOM   8717  C CG2    . ILE B 1 93  ? -20.311 6.326   -7.509  1.00 33.06  ? 93  ILE B CG2    1 
ATOM   8718  C CD1    . ILE B 1 93  ? -18.944 8.269   -9.391  1.00 29.86  ? 93  ILE B CD1    1 
ATOM   8719  H H      . ILE B 1 93  ? -22.769 6.568   -6.192  1.00 25.40  ? 93  ILE B H      1 
ATOM   8720  H HA     . ILE B 1 93  ? -22.707 8.578   -8.019  1.00 26.64  ? 93  ILE B HA     1 
ATOM   8721  H HB     . ILE B 1 93  ? -20.519 8.339   -7.198  1.00 30.35  ? 93  ILE B HB     1 
ATOM   8722  H HG12   . ILE B 1 93  ? -20.708 7.457   -9.885  1.00 33.03  ? 93  ILE B HG12   1 
ATOM   8723  H HG13   . ILE B 1 93  ? -20.826 8.980   -9.454  1.00 33.03  ? 93  ILE B HG13   1 
ATOM   8724  H HG21   . ILE B 1 93  ? -19.369 6.414   -7.306  1.00 39.67  ? 93  ILE B HG21   1 
ATOM   8725  H HG22   . ILE B 1 93  ? -20.781 5.968   -6.740  1.00 39.67  ? 93  ILE B HG22   1 
ATOM   8726  H HG23   . ILE B 1 93  ? -20.432 5.741   -8.273  1.00 39.67  ? 93  ILE B HG23   1 
ATOM   8727  H HD11   . ILE B 1 93  ? -18.751 8.675   -10.250 1.00 35.83  ? 93  ILE B HD11   1 
ATOM   8728  H HD12   . ILE B 1 93  ? -18.613 8.833   -8.675  1.00 35.83  ? 93  ILE B HD12   1 
ATOM   8729  H HD13   . ILE B 1 93  ? -18.533 7.392   -9.338  1.00 35.83  ? 93  ILE B HD13   1 
ATOM   8730  N N      . VAL B 1 94  ? -23.343 7.226   -9.937  1.00 22.67  ? 94  VAL B N      1 
ATOM   8731  C CA     . VAL B 1 94  ? -23.668 6.434   -11.122 1.00 21.56  ? 94  VAL B CA     1 
ATOM   8732  C C      . VAL B 1 94  ? -22.753 6.862   -12.277 1.00 20.39  ? 94  VAL B C      1 
ATOM   8733  O O      . VAL B 1 94  ? -22.817 8.009   -12.718 1.00 20.86  ? 94  VAL B O      1 
ATOM   8734  C CB     . VAL B 1 94  ? -25.142 6.616   -11.553 1.00 25.53  ? 94  VAL B CB     1 
ATOM   8735  C CG1    . VAL B 1 94  ? -25.466 5.739   -12.760 1.00 27.97  ? 94  VAL B CG1    1 
ATOM   8736  C CG2    . VAL B 1 94  ? -26.087 6.316   -10.385 1.00 29.54  ? 94  VAL B CG2    1 
ATOM   8737  H H      . VAL B 1 94  ? -23.446 8.071   -10.059 1.00 27.21  ? 94  VAL B H      1 
ATOM   8738  H HA     . VAL B 1 94  ? -23.531 5.496   -10.929 1.00 25.88  ? 94  VAL B HA     1 
ATOM   8739  H HB     . VAL B 1 94  ? -25.279 7.540   -11.814 1.00 30.64  ? 94  VAL B HB     1 
ATOM   8740  H HG11   . VAL B 1 94  ? -26.426 5.735   -12.896 1.00 33.57  ? 94  VAL B HG11   1 
ATOM   8741  H HG12   . VAL B 1 94  ? -25.023 6.100   -13.544 1.00 33.57  ? 94  VAL B HG12   1 
ATOM   8742  H HG13   . VAL B 1 94  ? -25.154 4.837   -12.587 1.00 33.57  ? 94  VAL B HG13   1 
ATOM   8743  H HG21   . VAL B 1 94  ? -27.003 6.379   -10.697 1.00 35.44  ? 94  VAL B HG21   1 
ATOM   8744  H HG22   . VAL B 1 94  ? -25.909 5.420   -10.058 1.00 35.44  ? 94  VAL B HG22   1 
ATOM   8745  H HG23   . VAL B 1 94  ? -25.933 6.963   -9.679  1.00 35.44  ? 94  VAL B HG23   1 
ATOM   8746  N N      . PRO B 1 95  ? -21.891 5.954   -12.761 1.00 20.06  ? 95  PRO B N      1 
ATOM   8747  C CA     . PRO B 1 95  ? -21.071 6.333   -13.922 1.00 19.67  ? 95  PRO B CA     1 
ATOM   8748  C C      . PRO B 1 95  ? -21.918 6.496   -15.180 1.00 19.21  ? 95  PRO B C      1 
ATOM   8749  O O      . PRO B 1 95  ? -22.960 5.861   -15.287 1.00 19.53  ? 95  PRO B O      1 
ATOM   8750  C CB     . PRO B 1 95  ? -20.086 5.171   -14.060 1.00 20.51  ? 95  PRO B CB     1 
ATOM   8751  C CG     . PRO B 1 95  ? -20.755 4.012   -13.410 1.00 27.57  ? 95  PRO B CG     1 
ATOM   8752  C CD     . PRO B 1 95  ? -21.638 4.566   -12.328 1.00 21.79  ? 95  PRO B CD     1 
ATOM   8753  H HA     . PRO B 1 95  ? -20.585 7.153   -13.746 1.00 23.60  ? 95  PRO B HA     1 
ATOM   8754  H HB2    . PRO B 1 95  ? -19.923 4.990   -14.999 1.00 24.61  ? 95  PRO B HB2    1 
ATOM   8755  H HB3    . PRO B 1 95  ? -19.258 5.389   -13.604 1.00 24.61  ? 95  PRO B HB3    1 
ATOM   8756  H HG2    . PRO B 1 95  ? -21.286 3.536   -14.068 1.00 33.08  ? 95  PRO B HG2    1 
ATOM   8757  H HG3    . PRO B 1 95  ? -20.083 3.425   -13.030 1.00 33.08  ? 95  PRO B HG3    1 
ATOM   8758  H HD2    . PRO B 1 95  ? -22.469 4.068   -12.287 1.00 26.14  ? 95  PRO B HD2    1 
ATOM   8759  H HD3    . PRO B 1 95  ? -21.175 4.557   -11.476 1.00 26.14  ? 95  PRO B HD3    1 
ATOM   8760  N N      . THR B 1 96  ? -21.488 7.373   -16.088 1.00 20.11  ? 96  THR B N      1 
ATOM   8761  C CA     . THR B 1 96  ? -22.140 7.562   -17.381 1.00 18.88  ? 96  THR B CA     1 
ATOM   8762  C C      . THR B 1 96  ? -21.039 7.714   -18.427 1.00 18.39  ? 96  THR B C      1 
ATOM   8763  O O      . THR B 1 96  ? -19.884 7.971   -18.067 1.00 19.22  ? 96  THR B O      1 
ATOM   8764  C CB     . THR B 1 96  ? -23.076 8.799   -17.390 1.00 20.22  ? 96  THR B CB     1 
ATOM   8765  O OG1    . THR B 1 96  ? -22.328 9.972   -17.043 1.00 20.73  ? 96  THR B OG1    1 
ATOM   8766  C CG2    . THR B 1 96  ? -24.208 8.623   -16.375 1.00 22.09  ? 96  THR B CG2    1 
ATOM   8767  H H      . THR B 1 96  ? -20.804 7.881   -15.973 1.00 24.13  ? 96  THR B H      1 
ATOM   8768  H HA     . THR B 1 96  ? -22.672 6.783   -17.598 1.00 22.66  ? 96  THR B HA     1 
ATOM   8769  H HB     . THR B 1 96  ? -23.464 8.909   -18.272 1.00 24.27  ? 96  THR B HB     1 
ATOM   8770  H HG1    . THR B 1 96  ? -21.724 10.107  -17.611 1.00 24.87  ? 96  THR B HG1    1 
ATOM   8771  H HG21   . THR B 1 96  ? -24.811 9.382   -16.416 1.00 26.51  ? 96  THR B HG21   1 
ATOM   8772  H HG22   . THR B 1 96  ? -24.706 7.814   -16.571 1.00 26.51  ? 96  THR B HG22   1 
ATOM   8773  H HG23   . THR B 1 96  ? -23.843 8.559   -15.479 1.00 26.51  ? 96  THR B HG23   1 
ATOM   8774  N N      . HIS B 1 97  ? -21.365 7.558   -19.711 1.00 18.81  ? 97  HIS B N      1 
ATOM   8775  C CA     . HIS B 1 97  ? -20.305 7.545   -20.720 1.00 21.17  ? 97  HIS B CA     1 
ATOM   8776  C C      . HIS B 1 97  ? -19.686 8.944   -20.867 1.00 20.67  ? 97  HIS B C      1 
ATOM   8777  O O      . HIS B 1 97  ? -18.507 9.078   -21.180 1.00 18.99  ? 97  HIS B O      1 
ATOM   8778  C CB     . HIS B 1 97  ? -20.819 7.007   -22.068 1.00 22.32  ? 97  HIS B CB     1 
ATOM   8779  C CG     . HIS B 1 97  ? -21.597 7.994   -22.877 1.00 24.84  ? 97  HIS B CG     1 
ATOM   8780  N ND1    . HIS B 1 97  ? -22.946 8.228   -22.681 1.00 22.91  ? 97  HIS B ND1    1 
ATOM   8781  C CD2    . HIS B 1 97  ? -21.233 8.790   -23.914 1.00 24.78  ? 97  HIS B CD2    1 
ATOM   8782  C CE1    . HIS B 1 97  ? -23.366 9.129   -23.545 1.00 24.96  ? 97  HIS B CE1    1 
ATOM   8783  N NE2    . HIS B 1 97  ? -22.345 9.493   -24.304 1.00 22.82  ? 97  HIS B NE2    1 
ATOM   8784  H H      . HIS B 1 97  ? -22.163 7.461   -20.016 1.00 22.57  ? 97  HIS B H      1 
ATOM   8785  H HA     . HIS B 1 97  ? -19.604 6.946   -20.420 1.00 25.40  ? 97  HIS B HA     1 
ATOM   8786  H HB2    . HIS B 1 97  ? -20.058 6.726   -22.600 1.00 26.78  ? 97  HIS B HB2    1 
ATOM   8787  H HB3    . HIS B 1 97  ? -21.396 6.246   -21.898 1.00 26.78  ? 97  HIS B HB3    1 
ATOM   8788  H HD1    . HIS B 1 97  ? -23.433 7.848   -22.084 1.00 27.49  ? 97  HIS B HD1    1 
ATOM   8789  H HD2    . HIS B 1 97  ? -20.382 8.858   -24.283 1.00 29.74  ? 97  HIS B HD2    1 
ATOM   8790  H HE1    . HIS B 1 97  ? -24.233 9.458   -23.606 1.00 29.95  ? 97  HIS B HE1    1 
ATOM   8791  H HE2    . HIS B 1 97  ? -22.374 10.070  -24.941 1.00 27.39  ? 97  HIS B HE2    1 
ATOM   8792  N N      . GLN B 1 98  ? -20.473 9.984   -20.620 1.00 18.63  ? 98  GLN B N      1 
ATOM   8793  C CA     . GLN B 1 98  ? -19.920 11.326  -20.441 1.00 19.95  ? 98  GLN B CA     1 
ATOM   8794  C C      . GLN B 1 98  ? -20.987 12.216  -19.802 1.00 21.94  ? 98  GLN B C      1 
ATOM   8795  O O      . GLN B 1 98  ? -22.032 11.729  -19.365 1.00 20.31  ? 98  GLN B O      1 
ATOM   8796  C CB     . GLN B 1 98  ? -19.402 11.919  -21.766 1.00 20.37  ? 98  GLN B CB     1 
ATOM   8797  C CG     . GLN B 1 98  ? -20.423 12.166  -22.857 1.00 20.48  ? 98  GLN B CG     1 
ATOM   8798  C CD     . GLN B 1 98  ? -19.764 12.560  -24.172 1.00 21.51  ? 98  GLN B CD     1 
ATOM   8799  O OE1    . GLN B 1 98  ? -18.923 11.827  -24.705 1.00 23.16  ? 98  GLN B OE1    1 
ATOM   8800  N NE2    . GLN B 1 98  ? -20.131 13.726  -24.695 1.00 21.52  ? 98  GLN B NE2    1 
ATOM   8801  H H      . GLN B 1 98  ? -21.329 9.942   -20.551 1.00 22.36  ? 98  GLN B H      1 
ATOM   8802  H HA     . GLN B 1 98  ? -19.171 11.276  -19.827 1.00 23.94  ? 98  GLN B HA     1 
ATOM   8803  H HB2    . GLN B 1 98  ? -18.979 12.768  -21.571 1.00 24.44  ? 98  GLN B HB2    1 
ATOM   8804  H HB3    . GLN B 1 98  ? -18.738 11.316  -22.133 1.00 24.44  ? 98  GLN B HB3    1 
ATOM   8805  H HG2    . GLN B 1 98  ? -20.934 11.356  -23.004 1.00 24.58  ? 98  GLN B HG2    1 
ATOM   8806  H HG3    . GLN B 1 98  ? -21.012 12.886  -22.585 1.00 24.58  ? 98  GLN B HG3    1 
ATOM   8807  H HE21   . GLN B 1 98  ? -20.708 14.217  -24.288 1.00 25.82  ? 98  GLN B HE21   1 
ATOM   8808  H HE22   . GLN B 1 98  ? -19.791 13.989  -25.440 1.00 25.82  ? 98  GLN B HE22   1 
ATOM   8809  N N      . GLY B 1 99  ? -20.716 13.510  -19.740 1.00 21.01  ? 99  GLY B N      1 
ATOM   8810  C CA     . GLY B 1 99  ? -21.547 14.427  -18.979 1.00 20.82  ? 99  GLY B CA     1 
ATOM   8811  C C      . GLY B 1 99  ? -23.016 14.434  -19.374 1.00 22.55  ? 99  GLY B C      1 
ATOM   8812  O O      . GLY B 1 99  ? -23.889 14.406  -18.509 1.00 21.02  ? 99  GLY B O      1 
ATOM   8813  H H      . GLY B 1 99  ? -20.050 13.886  -20.133 1.00 25.21  ? 99  GLY B H      1 
ATOM   8814  H HA2    . GLY B 1 99  ? -21.491 14.196  -18.039 1.00 24.99  ? 99  GLY B HA2    1 
ATOM   8815  H HA3    . GLY B 1 99  ? -21.204 15.328  -19.088 1.00 24.99  ? 99  GLY B HA3    1 
ATOM   8816  N N      . ARG B 1 100 ? -23.301 14.468  -20.673 1.00 20.38  ? 100 ARG B N      1 
ATOM   8817  C CA     . ARG B 1 100 ? -24.688 14.630  -21.119 1.00 22.57  ? 100 ARG B CA     1 
ATOM   8818  C C      . ARG B 1 100 ? -25.518 13.367  -20.865 1.00 22.91  ? 100 ARG B C      1 
ATOM   8819  O O      . ARG B 1 100 ? -26.748 13.423  -20.845 1.00 22.71  ? 100 ARG B O      1 
ATOM   8820  C CB     . ARG B 1 100 ? -24.748 15.046  -22.602 1.00 20.06  ? 100 ARG B CB     1 
ATOM   8821  C CG     . ARG B 1 100 ? -24.168 14.065  -23.597 1.00 19.14  ? 100 ARG B CG     1 
ATOM   8822  C CD     . ARG B 1 100 ? -23.812 14.778  -24.915 1.00 22.21  ? 100 ARG B CD     1 
ATOM   8823  N NE     . ARG B 1 100 ? -22.684 15.695  -24.741 1.00 20.77  ? 100 ARG B NE     1 
ATOM   8824  C CZ     . ARG B 1 100 ? -22.186 16.480  -25.691 1.00 20.15  ? 100 ARG B CZ     1 
ATOM   8825  N NH1    . ARG B 1 100 ? -22.729 16.501  -26.908 1.00 19.92  ? 100 ARG B NH1    1 
ATOM   8826  N NH2    . ARG B 1 100 ? -21.144 17.252  -25.405 1.00 21.42  ? 100 ARG B NH2    1 
ATOM   8827  H H      . ARG B 1 100 ? -22.724 14.401  -21.307 1.00 24.46  ? 100 ARG B H      1 
ATOM   8828  H HA     . ARG B 1 100 ? -25.090 15.343  -20.602 1.00 27.08  ? 100 ARG B HA     1 
ATOM   8829  H HB2    . ARG B 1 100 ? -25.678 15.183  -22.842 1.00 24.07  ? 100 ARG B HB2    1 
ATOM   8830  H HB3    . ARG B 1 100 ? -24.265 15.881  -22.702 1.00 24.07  ? 100 ARG B HB3    1 
ATOM   8831  H HG2    . ARG B 1 100 ? -23.359 13.673  -23.232 1.00 22.97  ? 100 ARG B HG2    1 
ATOM   8832  H HG3    . ARG B 1 100 ? -24.822 13.375  -23.789 1.00 22.97  ? 100 ARG B HG3    1 
ATOM   8833  H HD2    . ARG B 1 100 ? -23.567 14.117  -25.581 1.00 26.65  ? 100 ARG B HD2    1 
ATOM   8834  H HD3    . ARG B 1 100 ? -24.577 15.292  -25.218 1.00 26.65  ? 100 ARG B HD3    1 
ATOM   8835  H HE     . ARG B 1 100 ? -22.316 15.729  -23.964 1.00 24.92  ? 100 ARG B HE     1 
ATOM   8836  H HH11   . ARG B 1 100 ? -23.401 15.995  -27.085 1.00 23.90  ? 100 ARG B HH11   1 
ATOM   8837  H HH12   . ARG B 1 100 ? -22.412 17.012  -27.519 1.00 23.90  ? 100 ARG B HH12   1 
ATOM   8838  H HH21   . ARG B 1 100 ? -20.809 17.233  -24.613 1.00 25.70  ? 100 ARG B HH21   1 
ATOM   8839  H HH22   . ARG B 1 100 ? -20.810 17.778  -25.990 1.00 25.70  ? 100 ARG B HH22   1 
ATOM   8840  N N      . GLY B 1 101 ? -24.852 12.239  -20.630 1.00 22.53  ? 101 GLY B N      1 
ATOM   8841  C CA     . GLY B 1 101 ? -25.535 11.056  -20.138 1.00 20.49  ? 101 GLY B CA     1 
ATOM   8842  C C      . GLY B 1 101 ? -26.050 11.251  -18.720 1.00 23.89  ? 101 GLY B C      1 
ATOM   8843  O O      . GLY B 1 101 ? -27.166 10.844  -18.387 1.00 22.97  ? 101 GLY B O      1 
ATOM   8844  H H      . GLY B 1 101 ? -24.007 12.136  -20.749 1.00 27.04  ? 101 GLY B H      1 
ATOM   8845  H HA2    . GLY B 1 101 ? -26.287 10.849  -20.715 1.00 24.59  ? 101 GLY B HA2    1 
ATOM   8846  H HA3    . GLY B 1 101 ? -24.924 10.303  -20.144 1.00 24.59  ? 101 GLY B HA3    1 
ATOM   8847  N N      . ALA B 1 102 ? -25.234 11.869  -17.872 1.00 19.58  ? 102 ALA B N      1 
ATOM   8848  C CA     . ALA B 1 102 ? -25.641 12.144  -16.499 1.00 19.73  ? 102 ALA B CA     1 
ATOM   8849  C C      . ALA B 1 102 ? -26.768 13.181  -16.479 1.00 22.61  ? 102 ALA B C      1 
ATOM   8850  O O      . ALA B 1 102 ? -27.656 13.115  -15.646 1.00 23.11  ? 102 ALA B O      1 
ATOM   8851  C CB     . ALA B 1 102 ? -24.455 12.627  -15.675 1.00 20.88  ? 102 ALA B CB     1 
ATOM   8852  H H      . ALA B 1 102 ? -24.441 12.139  -18.067 1.00 23.49  ? 102 ALA B H      1 
ATOM   8853  H HA     . ALA B 1 102 ? -25.976 11.328  -16.096 1.00 23.68  ? 102 ALA B HA     1 
ATOM   8854  H HB1    . ALA B 1 102 ? -24.755 12.820  -14.773 1.00 25.06  ? 102 ALA B HB1    1 
ATOM   8855  H HB2    . ALA B 1 102 ? -23.779 11.932  -15.658 1.00 25.06  ? 102 ALA B HB2    1 
ATOM   8856  H HB3    . ALA B 1 102 ? -24.094 13.430  -16.082 1.00 25.06  ? 102 ALA B HB3    1 
ATOM   8857  N N      . GLU B 1 103 ? -26.722 14.133  -17.407 1.00 21.78  ? 103 GLU B N      1 
ATOM   8858  C CA     . GLU B 1 103 ? -27.769 15.155  -17.516 1.00 24.32  ? 103 GLU B CA     1 
ATOM   8859  C C      . GLU B 1 103 ? -29.111 14.546  -17.897 1.00 25.72  ? 103 GLU B C      1 
ATOM   8860  O O      . GLU B 1 103 ? -30.153 14.924  -17.355 1.00 24.08  ? 103 GLU B O      1 
ATOM   8861  C CB     . GLU B 1 103 ? -27.377 16.205  -18.552 1.00 24.01  ? 103 GLU B CB     1 
ATOM   8862  C CG     . GLU B 1 103 ? -26.207 17.046  -18.126 1.00 29.53  ? 103 GLU B CG     1 
ATOM   8863  C CD     . GLU B 1 103 ? -25.621 17.869  -19.257 1.00 34.46  ? 103 GLU B CD     1 
ATOM   8864  O OE1    . GLU B 1 103 ? -25.952 17.633  -20.443 1.00 28.38  ? 103 GLU B OE1    1 
ATOM   8865  O OE2    . GLU B 1 103 ? -24.824 18.768  -18.941 1.00 38.39  ? 103 GLU B OE2    1 
ATOM   8866  H H      . GLU B 1 103 ? -26.094 14.212  -17.989 1.00 26.14  ? 103 GLU B H      1 
ATOM   8867  H HA     . GLU B 1 103 ? -27.871 15.599  -16.659 1.00 29.18  ? 103 GLU B HA     1 
ATOM   8868  H HB2    . GLU B 1 103 ? -27.140 15.751  -19.375 1.00 28.81  ? 103 GLU B HB2    1 
ATOM   8869  H HB3    . GLU B 1 103 ? -28.131 16.795  -18.705 1.00 28.81  ? 103 GLU B HB3    1 
ATOM   8870  H HG2    . GLU B 1 103 ? -26.496 17.657  -17.430 1.00 35.44  ? 103 GLU B HG2    1 
ATOM   8871  H HG3    . GLU B 1 103 ? -25.508 16.465  -17.787 1.00 35.44  ? 103 GLU B HG3    1 
ATOM   8872  N N      . ASN B 1 104 ? -29.081 13.620  -18.852 1.00 22.61  ? 104 ASN B N      1 
ATOM   8873  C CA     . ASN B 1 104 ? -30.273 12.875  -19.234 1.00 25.16  ? 104 ASN B CA     1 
ATOM   8874  C C      . ASN B 1 104 ? -30.909 12.235  -18.008 1.00 26.28  ? 104 ASN B C      1 
ATOM   8875  O O      . ASN B 1 104 ? -32.112 12.351  -17.796 1.00 27.78  ? 104 ASN B O      1 
ATOM   8876  C CB     . ASN B 1 104 ? -29.933 11.808  -20.278 1.00 22.74  ? 104 ASN B CB     1 
ATOM   8877  C CG     . ASN B 1 104 ? -31.132 10.959  -20.665 1.00 32.51  ? 104 ASN B CG     1 
ATOM   8878  O OD1    . ASN B 1 104 ? -32.252 11.459  -20.786 1.00 32.24  ? 104 ASN B OD1    1 
ATOM   8879  N ND2    . ASN B 1 104 ? -30.902 9.661   -20.857 1.00 34.72  ? 104 ASN B ND2    1 
ATOM   8880  H H      . ASN B 1 104 ? -28.377 13.404  -19.296 1.00 27.13  ? 104 ASN B H      1 
ATOM   8881  H HA     . ASN B 1 104 ? -30.918 13.485  -19.625 1.00 30.19  ? 104 ASN B HA     1 
ATOM   8882  H HB2    . ASN B 1 104 ? -29.603 12.244  -21.079 1.00 27.28  ? 104 ASN B HB2    1 
ATOM   8883  H HB3    . ASN B 1 104 ? -29.252 11.219  -19.917 1.00 27.28  ? 104 ASN B HB3    1 
ATOM   8884  H HD21   . ASN B 1 104 ? -31.549 9.137   -21.072 1.00 41.66  ? 104 ASN B HD21   1 
ATOM   8885  H HD22   . ASN B 1 104 ? -30.107 9.347   -20.766 1.00 41.66  ? 104 ASN B HD22   1 
ATOM   8886  N N      . LEU B 1 105 ? -30.098 11.575  -17.186 1.00 23.67  ? 105 LEU B N      1 
ATOM   8887  C CA     . LEU B 1 105 ? -30.612 10.928  -15.980 1.00 25.91  ? 105 LEU B CA     1 
ATOM   8888  C C      . LEU B 1 105 ? -31.184 11.928  -14.984 1.00 27.30  ? 105 LEU B C      1 
ATOM   8889  O O      . LEU B 1 105 ? -32.305 11.761  -14.517 1.00 26.76  ? 105 LEU B O      1 
ATOM   8890  C CB     . LEU B 1 105 ? -29.519 10.103  -15.291 1.00 24.49  ? 105 LEU B CB     1 
ATOM   8891  C CG     . LEU B 1 105 ? -28.907 8.942   -16.079 1.00 28.33  ? 105 LEU B CG     1 
ATOM   8892  C CD1    . LEU B 1 105 ? -27.868 8.229   -15.217 1.00 26.85  ? 105 LEU B CD1    1 
ATOM   8893  C CD2    . LEU B 1 105 ? -29.975 7.968   -16.557 1.00 30.86  ? 105 LEU B CD2    1 
ATOM   8894  H H      . LEU B 1 105 ? -29.250 11.487  -17.302 1.00 28.41  ? 105 LEU B H      1 
ATOM   8895  H HA     . LEU B 1 105 ? -31.328 10.324  -16.232 1.00 31.09  ? 105 LEU B HA     1 
ATOM   8896  H HB2    . LEU B 1 105 ? -28.793 10.702  -15.059 1.00 29.39  ? 105 LEU B HB2    1 
ATOM   8897  H HB3    . LEU B 1 105 ? -29.894 9.728   -14.479 1.00 29.39  ? 105 LEU B HB3    1 
ATOM   8898  H HG     . LEU B 1 105 ? -28.455 9.295   -16.860 1.00 34.00  ? 105 LEU B HG     1 
ATOM   8899  H HD11   . LEU B 1 105 ? -27.486 7.496   -15.725 1.00 32.22  ? 105 LEU B HD11   1 
ATOM   8900  H HD12   . LEU B 1 105 ? -27.173 8.861   -14.974 1.00 32.22  ? 105 LEU B HD12   1 
ATOM   8901  H HD13   . LEU B 1 105 ? -28.301 7.889   -14.418 1.00 32.22  ? 105 LEU B HD13   1 
ATOM   8902  H HD21   . LEU B 1 105 ? -29.542 7.208   -16.976 1.00 37.04  ? 105 LEU B HD21   1 
ATOM   8903  H HD22   . LEU B 1 105 ? -30.497 7.673   -15.795 1.00 37.04  ? 105 LEU B HD22   1 
ATOM   8904  H HD23   . LEU B 1 105 ? -30.548 8.416   -17.198 1.00 37.04  ? 105 LEU B HD23   1 
ATOM   8905  N N      . LEU B 1 106 ? -30.414 12.960  -14.648 1.00 24.95  ? 106 LEU B N      1 
ATOM   8906  C CA     . LEU B 1 106 ? -30.842 13.925  -13.640 1.00 26.44  ? 106 LEU B CA     1 
ATOM   8907  C C      . LEU B 1 106 ? -32.163 14.593  -14.017 1.00 29.87  ? 106 LEU B C      1 
ATOM   8908  O O      . LEU B 1 106 ? -33.086 14.648  -13.208 1.00 27.70  ? 106 LEU B O      1 
ATOM   8909  C CB     . LEU B 1 106 ? -29.772 14.997  -13.429 1.00 25.75  ? 106 LEU B CB     1 
ATOM   8910  C CG     . LEU B 1 106 ? -30.162 16.126  -12.466 1.00 27.89  ? 106 LEU B CG     1 
ATOM   8911  C CD1    . LEU B 1 106 ? -30.396 15.568  -11.074 1.00 27.66  ? 106 LEU B CD1    1 
ATOM   8912  C CD2    . LEU B 1 106 ? -29.097 17.204  -12.442 1.00 28.93  ? 106 LEU B CD2    1 
ATOM   8913  H H      . LEU B 1 106 ? -29.641 13.123  -14.988 1.00 29.94  ? 106 LEU B H      1 
ATOM   8914  H HA     . LEU B 1 106 ? -30.972 13.461  -12.798 1.00 31.72  ? 106 LEU B HA     1 
ATOM   8915  H HB2    . LEU B 1 106 ? -28.976 14.572  -13.073 1.00 30.90  ? 106 LEU B HB2    1 
ATOM   8916  H HB3    . LEU B 1 106 ? -29.568 15.402  -14.287 1.00 30.90  ? 106 LEU B HB3    1 
ATOM   8917  H HG     . LEU B 1 106 ? -30.986 16.539  -12.766 1.00 33.47  ? 106 LEU B HG     1 
ATOM   8918  H HD11   . LEU B 1 106 ? -30.540 16.305  -10.460 1.00 33.20  ? 106 LEU B HD11   1 
ATOM   8919  H HD12   . LEU B 1 106 ? -31.178 14.994  -11.090 1.00 33.20  ? 106 LEU B HD12   1 
ATOM   8920  H HD13   . LEU B 1 106 ? -29.616 15.059  -10.803 1.00 33.20  ? 106 LEU B HD13   1 
ATOM   8921  H HD21   . LEU B 1 106 ? -29.370 17.903  -11.827 1.00 34.72  ? 106 LEU B HD21   1 
ATOM   8922  H HD22   . LEU B 1 106 ? -28.259 16.813  -12.149 1.00 34.72  ? 106 LEU B HD22   1 
ATOM   8923  H HD23   . LEU B 1 106 ? -28.997 17.569  -13.335 1.00 34.72  ? 106 LEU B HD23   1 
ATOM   8924  N N      . SER B 1 107 ? -32.244 15.104  -15.240 1.00 23.55  ? 107 SER B N      1 
ATOM   8925  C CA     . SER B 1 107 ? -33.433 15.830  -15.684 1.00 28.70  ? 107 SER B CA     1 
ATOM   8926  C C      . SER B 1 107 ? -34.646 14.910  -15.820 1.00 32.43  ? 107 SER B C      1 
ATOM   8927  O O      . SER B 1 107 ? -35.783 15.346  -15.642 1.00 29.38  ? 107 SER B O      1 
ATOM   8928  C CB     . SER B 1 107 ? -33.160 16.537  -17.013 1.00 29.23  ? 107 SER B CB     1 
ATOM   8929  O OG     . SER B 1 107 ? -32.218 17.587  -16.842 1.00 27.78  ? 107 SER B OG     1 
ATOM   8930  H H      . SER B 1 107 ? -31.625 15.045  -15.834 1.00 28.25  ? 107 SER B H      1 
ATOM   8931  H HA     . SER B 1 107 ? -33.648 16.509  -15.026 1.00 34.44  ? 107 SER B HA     1 
ATOM   8932  H HB2    . SER B 1 107 ? -32.804 15.894  -17.646 1.00 35.07  ? 107 SER B HB2    1 
ATOM   8933  H HB3    . SER B 1 107 ? -33.990 16.909  -17.349 1.00 35.07  ? 107 SER B HB3    1 
ATOM   8934  H HG     . SER B 1 107 ? -32.514 18.152  -16.295 1.00 33.33  ? 107 SER B HG     1 
ATOM   8935  N N      . SER B 1 108 ? -34.399 13.641  -16.135 1.00 27.25  ? 108 SER B N      1 
ATOM   8936  C CA     . SER B 1 108 ? -35.468 12.662  -16.262 1.00 32.15  ? 108 SER B CA     1 
ATOM   8937  C C      . SER B 1 108 ? -36.054 12.295  -14.907 1.00 32.85  ? 108 SER B C      1 
ATOM   8938  O O      . SER B 1 108 ? -37.191 11.846  -14.829 1.00 34.75  ? 108 SER B O      1 
ATOM   8939  C CB     . SER B 1 108 ? -34.959 11.399  -16.960 1.00 32.13  ? 108 SER B CB     1 
ATOM   8940  O OG     . SER B 1 108 ? -34.598 11.670  -18.305 1.00 44.82  ? 108 SER B OG     1 
ATOM   8941  H H      . SER B 1 108 ? -33.614 13.322  -16.281 1.00 32.70  ? 108 SER B H      1 
ATOM   8942  H HA     . SER B 1 108 ? -36.179 13.037  -16.800 1.00 38.58  ? 108 SER B HA     1 
ATOM   8943  H HB2    . SER B 1 108 ? -34.180 11.070  -16.485 1.00 38.56  ? 108 SER B HB2    1 
ATOM   8944  H HB3    . SER B 1 108 ? -35.660 10.729  -16.950 1.00 38.56  ? 108 SER B HB3    1 
ATOM   8945  H HG     . SER B 1 108 ? -33.990 12.249  -18.328 1.00 53.79  ? 108 SER B HG     1 
ATOM   8946  N N      . LEU B 1 109 ? -35.273 12.497  -13.849 1.00 29.55  ? 109 LEU B N      1 
ATOM   8947  C CA     . LEU B 1 109 ? -35.668 12.111  -12.495 1.00 30.55  ? 109 LEU B CA     1 
ATOM   8948  C C      . LEU B 1 109 ? -36.201 13.270  -11.650 1.00 35.91  ? 109 LEU B C      1 
ATOM   8949  O O      . LEU B 1 109 ? -37.051 13.072  -10.782 1.00 32.30  ? 109 LEU B O      1 
ATOM   8950  C CB     . LEU B 1 109 ? -34.477 11.494  -11.762 1.00 28.74  ? 109 LEU B CB     1 
ATOM   8951  C CG     . LEU B 1 109 ? -33.941 10.167  -12.296 1.00 34.89  ? 109 LEU B CG     1 
ATOM   8952  C CD1    . LEU B 1 109 ? -32.607 9.859   -11.647 1.00 32.55  ? 109 LEU B CD1    1 
ATOM   8953  C CD2    . LEU B 1 109 ? -34.925 9.052   -12.032 1.00 36.75  ? 109 LEU B CD2    1 
ATOM   8954  H H      . LEU B 1 109 ? -34.495 12.861  -13.888 1.00 35.46  ? 109 LEU B H      1 
ATOM   8955  H HA     . LEU B 1 109 ? -36.364 11.438  -12.545 1.00 36.66  ? 109 LEU B HA     1 
ATOM   8956  H HB2    . LEU B 1 109 ? -33.745 12.130  -11.790 1.00 34.49  ? 109 LEU B HB2    1 
ATOM   8957  H HB3    . LEU B 1 109 ? -34.736 11.346  -10.839 1.00 34.49  ? 109 LEU B HB3    1 
ATOM   8958  H HG     . LEU B 1 109 ? -33.809 10.233  -13.254 1.00 41.87  ? 109 LEU B HG     1 
ATOM   8959  H HD11   . LEU B 1 109 ? -32.225 9.075   -12.071 1.00 39.06  ? 109 LEU B HD11   1 
ATOM   8960  H HD12   . LEU B 1 109 ? -32.016 10.619  -11.764 1.00 39.06  ? 109 LEU B HD12   1 
ATOM   8961  H HD13   . LEU B 1 109 ? -32.747 9.691   -10.702 1.00 39.06  ? 109 LEU B HD13   1 
ATOM   8962  H HD21   . LEU B 1 109 ? -34.538 8.213   -12.329 1.00 44.10  ? 109 LEU B HD21   1 
ATOM   8963  H HD22   . LEU B 1 109 ? -35.109 9.013   -11.080 1.00 44.10  ? 109 LEU B HD22   1 
ATOM   8964  H HD23   . LEU B 1 109 ? -35.744 9.230   -12.521 1.00 44.10  ? 109 LEU B HD23   1 
ATOM   8965  N N      . ALA B 1 110 ? -35.689 14.472  -11.893 1.00 31.76  ? 110 ALA B N      1 
ATOM   8966  C CA     . ALA B 1 110 ? -35.880 15.582  -10.958 1.00 34.44  ? 110 ALA B CA     1 
ATOM   8967  C C      . ALA B 1 110 ? -36.838 16.667  -11.460 1.00 32.15  ? 110 ALA B C      1 
ATOM   8968  O O      . ALA B 1 110 ? -37.073 17.648  -10.754 1.00 35.82  ? 110 ALA B O      1 
ATOM   8969  C CB     . ALA B 1 110 ? -34.527 16.202  -10.629 1.00 31.69  ? 110 ALA B CB     1 
ATOM   8970  H H      . ALA B 1 110 ? -35.227 14.673  -12.590 1.00 38.11  ? 110 ALA B H      1 
ATOM   8971  H HA     . ALA B 1 110 ? -36.244 15.239  -10.127 1.00 41.33  ? 110 ALA B HA     1 
ATOM   8972  H HB1    . ALA B 1 110 ? -34.658 16.933  -10.005 1.00 38.03  ? 110 ALA B HB1    1 
ATOM   8973  H HB2    . ALA B 1 110 ? -33.958 15.524  -10.231 1.00 38.03  ? 110 ALA B HB2    1 
ATOM   8974  H HB3    . ALA B 1 110 ? -34.124 16.533  -11.447 1.00 38.03  ? 110 ALA B HB3    1 
ATOM   8975  N N      . ILE B 1 111 ? -37.388 16.493  -12.660 1.00 29.71  ? 111 ILE B N      1 
ATOM   8976  C CA     . ILE B 1 111 ? -38.241 17.508  -13.276 1.00 35.43  ? 111 ILE B CA     1 
ATOM   8977  C C      . ILE B 1 111 ? -39.640 16.977  -13.583 1.00 44.28  ? 111 ILE B C      1 
ATOM   8978  O O      . ILE B 1 111 ? -39.799 16.013  -14.335 1.00 40.19  ? 111 ILE B O      1 
ATOM   8979  C CB     . ILE B 1 111 ? -37.626 18.046  -14.590 1.00 36.15  ? 111 ILE B CB     1 
ATOM   8980  C CG1    . ILE B 1 111 ? -36.249 18.655  -14.324 1.00 29.22  ? 111 ILE B CG1    1 
ATOM   8981  C CG2    . ILE B 1 111 ? -38.543 19.098  -15.234 1.00 34.58  ? 111 ILE B CG2    1 
ATOM   8982  C CD1    . ILE B 1 111 ? -35.515 19.109  -15.580 1.00 31.39  ? 111 ILE B CD1    1 
ATOM   8983  H H      . ILE B 1 111 ? -37.282 15.789  -13.143 1.00 35.65  ? 111 ILE B H      1 
ATOM   8984  H HA     . ILE B 1 111 ? -38.342 18.260  -12.673 1.00 42.52  ? 111 ILE B HA     1 
ATOM   8985  H HB     . ILE B 1 111 ? -37.523 17.306  -15.209 1.00 43.38  ? 111 ILE B HB     1 
ATOM   8986  H HG12   . ILE B 1 111 ? -36.357 19.429  -13.749 1.00 35.07  ? 111 ILE B HG12   1 
ATOM   8987  H HG13   . ILE B 1 111 ? -35.694 17.994  -13.883 1.00 35.07  ? 111 ILE B HG13   1 
ATOM   8988  H HG21   . ILE B 1 111 ? -38.123 19.426  -16.043 1.00 41.50  ? 111 ILE B HG21   1 
ATOM   8989  H HG22   . ILE B 1 111 ? -39.396 18.696  -15.459 1.00 41.50  ? 111 ILE B HG22   1 
ATOM   8990  H HG23   . ILE B 1 111 ? -38.674 19.828  -14.609 1.00 41.50  ? 111 ILE B HG23   1 
ATOM   8991  H HD11   . ILE B 1 111 ? -34.588 19.287  -15.356 1.00 37.66  ? 111 ILE B HD11   1 
ATOM   8992  H HD12   . ILE B 1 111 ? -35.565 18.405  -16.246 1.00 37.66  ? 111 ILE B HD12   1 
ATOM   8993  H HD13   . ILE B 1 111 ? -35.934 19.915  -15.919 1.00 37.66  ? 111 ILE B HD13   1 
ATOM   8994  N N      . LYS B 1 112 ? -40.643 17.625  -12.996 1.00 46.31  ? 112 LYS B N      1 
ATOM   8995  C CA     . LYS B 1 112 ? -42.040 17.407  -13.361 1.00 47.68  ? 112 LYS B CA     1 
ATOM   8996  C C      . LYS B 1 112 ? -42.430 18.442  -14.421 1.00 45.66  ? 112 LYS B C      1 
ATOM   8997  O O      . LYS B 1 112 ? -41.942 19.574  -14.391 1.00 42.59  ? 112 LYS B O      1 
ATOM   8998  C CB     . LYS B 1 112 ? -42.948 17.515  -12.133 1.00 50.52  ? 112 LYS B CB     1 
ATOM   8999  C CG     . LYS B 1 112 ? -42.551 16.581  -10.994 1.00 61.91  ? 112 LYS B CG     1 
ATOM   9000  C CD     . LYS B 1 112 ? -43.367 16.817  -9.727  1.00 60.70  ? 112 LYS B CD     1 
ATOM   9001  C CE     . LYS B 1 112 ? -42.853 15.946  -8.584  1.00 80.86  ? 112 LYS B CE     1 
ATOM   9002  N NZ     . LYS B 1 112 ? -43.569 16.177  -7.298  1.00 78.57  ? 112 LYS B NZ     1 
ATOM   9003  H H      . LYS B 1 112 ? -40.538 18.207  -12.372 1.00 55.57  ? 112 LYS B H      1 
ATOM   9004  H HA     . LYS B 1 112 ? -42.135 16.516  -13.728 1.00 57.22  ? 112 LYS B HA     1 
ATOM   9005  H HB2    . LYS B 1 112 ? -42.913 18.424  -11.797 1.00 60.62  ? 112 LYS B HB2    1 
ATOM   9006  H HB3    . LYS B 1 112 ? -43.856 17.295  -12.395 1.00 60.62  ? 112 LYS B HB3    1 
ATOM   9007  H HG2    . LYS B 1 112 ? -42.691 15.663  -11.275 1.00 74.29  ? 112 LYS B HG2    1 
ATOM   9008  H HG3    . LYS B 1 112 ? -41.616 16.723  -10.778 1.00 74.29  ? 112 LYS B HG3    1 
ATOM   9009  H HD2    . LYS B 1 112 ? -43.290 17.747  -9.462  1.00 72.84  ? 112 LYS B HD2    1 
ATOM   9010  H HD3    . LYS B 1 112 ? -44.295 16.588  -9.893  1.00 72.84  ? 112 LYS B HD3    1 
ATOM   9011  H HE2    . LYS B 1 112 ? -42.966 15.013  -8.825  1.00 97.03  ? 112 LYS B HE2    1 
ATOM   9012  H HE3    . LYS B 1 112 ? -41.913 16.138  -8.441  1.00 97.03  ? 112 LYS B HE3    1 
ATOM   9013  H HZ1    . LYS B 1 112 ? -43.235 15.648  -6.665  1.00 94.29  ? 112 LYS B HZ1    1 
ATOM   9014  H HZ2    . LYS B 1 112 ? -43.475 17.025  -7.046  1.00 94.29  ? 112 LYS B HZ2    1 
ATOM   9015  H HZ3    . LYS B 1 112 ? -44.435 15.999  -7.396  1.00 94.29  ? 112 LYS B HZ3    1 
ATOM   9016  N N      . PRO B 1 113 ? -43.298 18.062  -15.371 1.00 47.77  ? 113 PRO B N      1 
ATOM   9017  C CA     . PRO B 1 113 ? -43.691 19.024  -16.410 1.00 45.63  ? 113 PRO B CA     1 
ATOM   9018  C C      . PRO B 1 113 ? -44.281 20.314  -15.827 1.00 42.10  ? 113 PRO B C      1 
ATOM   9019  O O      . PRO B 1 113 ? -44.980 20.265  -14.815 1.00 41.21  ? 113 PRO B O      1 
ATOM   9020  C CB     . PRO B 1 113 ? -44.740 18.255  -17.222 1.00 46.81  ? 113 PRO B CB     1 
ATOM   9021  C CG     . PRO B 1 113 ? -44.423 16.815  -16.986 1.00 49.09  ? 113 PRO B CG     1 
ATOM   9022  C CD     . PRO B 1 113 ? -43.926 16.743  -15.574 1.00 52.70  ? 113 PRO B CD     1 
ATOM   9023  H HA     . PRO B 1 113 ? -42.935 19.240  -16.977 1.00 54.75  ? 113 PRO B HA     1 
ATOM   9024  H HB2    . PRO B 1 113 ? -45.628 18.470  -16.897 1.00 56.17  ? 113 PRO B HB2    1 
ATOM   9025  H HB3    . PRO B 1 113 ? -44.654 18.477  -18.162 1.00 56.17  ? 113 PRO B HB3    1 
ATOM   9026  H HG2    . PRO B 1 113 ? -45.226 16.282  -17.094 1.00 58.91  ? 113 PRO B HG2    1 
ATOM   9027  H HG3    . PRO B 1 113 ? -43.735 16.527  -17.606 1.00 58.91  ? 113 PRO B HG3    1 
ATOM   9028  H HD2    . PRO B 1 113 ? -44.666 16.621  -14.959 1.00 63.24  ? 113 PRO B HD2    1 
ATOM   9029  H HD3    . PRO B 1 113 ? -43.271 16.033  -15.490 1.00 63.24  ? 113 PRO B HD3    1 
ATOM   9030  N N      . GLY B 1 114 ? -43.969 21.446  -16.452 1.00 39.29  ? 114 GLY B N      1 
ATOM   9031  C CA     . GLY B 1 114 ? -44.450 22.742  -16.003 1.00 40.59  ? 114 GLY B CA     1 
ATOM   9032  C C      . GLY B 1 114 ? -43.586 23.426  -14.954 1.00 44.40  ? 114 GLY B C      1 
ATOM   9033  O O      . GLY B 1 114 ? -43.875 24.555  -14.554 1.00 44.30  ? 114 GLY B O      1 
ATOM   9034  H H      . GLY B 1 114 ? -43.470 21.487  -17.152 1.00 47.15  ? 114 GLY B H      1 
ATOM   9035  H HA2    . GLY B 1 114 ? -44.511 23.334  -16.769 1.00 48.71  ? 114 GLY B HA2    1 
ATOM   9036  H HA3    . GLY B 1 114 ? -45.341 22.639  -15.635 1.00 48.71  ? 114 GLY B HA3    1 
ATOM   9037  N N      . GLN B 1 115 ? -42.529 22.755  -14.503 1.00 40.45  ? 115 GLN B N      1 
ATOM   9038  C CA     . GLN B 1 115 ? -41.639 23.331  -13.498 1.00 34.86  ? 115 GLN B CA     1 
ATOM   9039  C C      . GLN B 1 115 ? -40.583 24.235  -14.122 1.00 37.09  ? 115 GLN B C      1 
ATOM   9040  O O      . GLN B 1 115 ? -40.457 24.312  -15.343 1.00 36.19  ? 115 GLN B O      1 
ATOM   9041  C CB     . GLN B 1 115 ? -40.952 22.236  -12.689 1.00 37.10  ? 115 GLN B CB     1 
ATOM   9042  C CG     . GLN B 1 115 ? -41.863 21.522  -11.705 1.00 39.09  ? 115 GLN B CG     1 
ATOM   9043  C CD     . GLN B 1 115 ? -41.095 20.618  -10.762 1.00 40.79  ? 115 GLN B CD     1 
ATOM   9044  O OE1    . GLN B 1 115 ? -40.377 19.718  -11.195 1.00 39.61  ? 115 GLN B OE1    1 
ATOM   9045  N NE2    . GLN B 1 115 ? -41.233 20.861  -9.464  1.00 41.73  ? 115 GLN B NE2    1 
ATOM   9046  H H      . GLN B 1 115 ? -42.305 21.966  -14.761 1.00 48.54  ? 115 GLN B H      1 
ATOM   9047  H HA     . GLN B 1 115 ? -42.163 23.866  -12.882 1.00 41.84  ? 115 GLN B HA     1 
ATOM   9048  H HB2    . GLN B 1 115 ? -40.601 21.571  -13.302 1.00 44.52  ? 115 GLN B HB2    1 
ATOM   9049  H HB3    . GLN B 1 115 ? -40.225 22.630  -12.182 1.00 44.52  ? 115 GLN B HB3    1 
ATOM   9050  H HG2    . GLN B 1 115 ? -42.335 22.182  -11.173 1.00 46.91  ? 115 GLN B HG2    1 
ATOM   9051  H HG3    . GLN B 1 115 ? -42.496 20.976  -12.197 1.00 46.91  ? 115 GLN B HG3    1 
ATOM   9052  H HE21   . GLN B 1 115 ? -41.738 21.504  -9.198  1.00 50.08  ? 115 GLN B HE21   1 
ATOM   9053  H HE22   . GLN B 1 115 ? -40.817 20.375  -8.889  1.00 50.08  ? 115 GLN B HE22   1 
ATOM   9054  N N      . TYR B 1 116 ? -39.838 24.929  -13.268 1.00 33.56  ? 116 TYR B N      1 
ATOM   9055  C CA     . TYR B 1 116 ? -38.742 25.779  -13.713 1.00 32.90  ? 116 TYR B CA     1 
ATOM   9056  C C      . TYR B 1 116 ? -37.393 25.238  -13.245 1.00 33.05  ? 116 TYR B C      1 
ATOM   9057  O O      . TYR B 1 116 ? -37.275 24.676  -12.156 1.00 34.92  ? 116 TYR B O      1 
ATOM   9058  C CB     . TYR B 1 116 ? -38.940 27.207  -13.203 1.00 38.21  ? 116 TYR B CB     1 
ATOM   9059  C CG     . TYR B 1 116 ? -40.176 27.871  -13.763 1.00 39.80  ? 116 TYR B CG     1 
ATOM   9060  C CD1    . TYR B 1 116 ? -41.406 27.732  -13.134 1.00 44.20  ? 116 TYR B CD1    1 
ATOM   9061  C CD2    . TYR B 1 116 ? -40.115 28.625  -14.926 1.00 38.49  ? 116 TYR B CD2    1 
ATOM   9062  C CE1    . TYR B 1 116 ? -42.543 28.330  -13.647 1.00 47.27  ? 116 TYR B CE1    1 
ATOM   9063  C CE2    . TYR B 1 116 ? -41.247 29.228  -15.448 1.00 40.93  ? 116 TYR B CE2    1 
ATOM   9064  C CZ     . TYR B 1 116 ? -42.457 29.080  -14.801 1.00 50.33  ? 116 TYR B CZ     1 
ATOM   9065  O OH     . TYR B 1 116 ? -43.587 29.674  -15.313 1.00 62.79  ? 116 TYR B OH     1 
ATOM   9066  H H      . TYR B 1 116 ? -39.950 24.924  -12.415 1.00 40.27  ? 116 TYR B H      1 
ATOM   9067  H HA     . TYR B 1 116 ? -38.725 25.814  -14.681 1.00 39.48  ? 116 TYR B HA     1 
ATOM   9068  H HB2    . TYR B 1 116 ? -39.023 27.187  -12.237 1.00 45.85  ? 116 TYR B HB2    1 
ATOM   9069  H HB3    . TYR B 1 116 ? -38.172 27.742  -13.458 1.00 45.85  ? 116 TYR B HB3    1 
ATOM   9070  H HD1    . TYR B 1 116 ? -41.467 27.228  -12.355 1.00 53.04  ? 116 TYR B HD1    1 
ATOM   9071  H HD2    . TYR B 1 116 ? -39.300 28.727  -15.362 1.00 46.19  ? 116 TYR B HD2    1 
ATOM   9072  H HE1    . TYR B 1 116 ? -43.360 28.231  -13.213 1.00 56.72  ? 116 TYR B HE1    1 
ATOM   9073  H HE2    . TYR B 1 116 ? -41.191 29.733  -16.227 1.00 49.11  ? 116 TYR B HE2    1 
ATOM   9074  H HH     . TYR B 1 116 ? -43.397 30.098  -16.013 1.00 75.34  ? 116 TYR B HH     1 
ATOM   9075  N N      . VAL B 1 117 ? -36.383 25.392  -14.094 1.00 31.27  ? 117 VAL B N      1 
ATOM   9076  C CA     . VAL B 1 117 ? -35.001 25.176  -13.695 1.00 30.46  ? 117 VAL B CA     1 
ATOM   9077  C C      . VAL B 1 117 ? -34.269 26.499  -13.856 1.00 29.83  ? 117 VAL B C      1 
ATOM   9078  O O      . VAL B 1 117 ? -34.314 27.108  -14.917 1.00 28.80  ? 117 VAL B O      1 
ATOM   9079  C CB     . VAL B 1 117 ? -34.316 24.074  -14.529 1.00 32.75  ? 117 VAL B CB     1 
ATOM   9080  C CG1    . VAL B 1 117 ? -32.805 24.036  -14.245 1.00 33.12  ? 117 VAL B CG1    1 
ATOM   9081  C CG2    . VAL B 1 117 ? -34.949 22.717  -14.239 1.00 29.10  ? 117 VAL B CG2    1 
ATOM   9082  H H      . VAL B 1 117 ? -36.475 25.624  -14.917 1.00 37.53  ? 117 VAL B H      1 
ATOM   9083  H HA     . VAL B 1 117 ? -34.958 24.920  -12.761 1.00 36.55  ? 117 VAL B HA     1 
ATOM   9084  H HB     . VAL B 1 117 ? -34.440 24.268  -15.471 1.00 39.30  ? 117 VAL B HB     1 
ATOM   9085  H HG11   . VAL B 1 117 ? -32.447 23.193  -14.565 1.00 39.75  ? 117 VAL B HG11   1 
ATOM   9086  H HG12   . VAL B 1 117 ? -32.375 24.773  -14.707 1.00 39.75  ? 117 VAL B HG12   1 
ATOM   9087  H HG13   . VAL B 1 117 ? -32.662 24.113  -13.289 1.00 39.75  ? 117 VAL B HG13   1 
ATOM   9088  H HG21   . VAL B 1 117 ? -34.506 22.041  -14.775 1.00 34.92  ? 117 VAL B HG21   1 
ATOM   9089  H HG22   . VAL B 1 117 ? -34.842 22.514  -13.296 1.00 34.92  ? 117 VAL B HG22   1 
ATOM   9090  H HG23   . VAL B 1 117 ? -35.892 22.754  -14.465 1.00 34.92  ? 117 VAL B HG23   1 
ATOM   9091  N N      . ALA B 1 118 ? -33.621 26.951  -12.790 1.00 28.51  ? 118 ALA B N      1 
ATOM   9092  C CA     . ALA B 1 118 ? -32.880 28.201  -12.821 1.00 31.64  ? 118 ALA B CA     1 
ATOM   9093  C C      . ALA B 1 118 ? -31.395 27.914  -12.690 1.00 30.74  ? 118 ALA B C      1 
ATOM   9094  O O      . ALA B 1 118 ? -30.987 27.067  -11.892 1.00 30.68  ? 118 ALA B O      1 
ATOM   9095  C CB     . ALA B 1 118 ? -33.345 29.124  -11.713 1.00 37.65  ? 118 ALA B CB     1 
ATOM   9096  H H      . ALA B 1 118 ? -33.596 26.548  -12.031 1.00 34.21  ? 118 ALA B H      1 
ATOM   9097  H HA     . ALA B 1 118 ? -33.029 28.647  -13.664 1.00 37.97  ? 118 ALA B HA     1 
ATOM   9098  H HB1    . ALA B 1 118 ? -32.874 29.968  -11.789 1.00 45.18  ? 118 ALA B HB1    1 
ATOM   9099  H HB2    . ALA B 1 118 ? -34.300 29.268  -11.805 1.00 45.18  ? 118 ALA B HB2    1 
ATOM   9100  H HB3    . ALA B 1 118 ? -33.154 28.711  -10.856 1.00 45.18  ? 118 ALA B HB3    1 
ATOM   9101  N N      . GLY B 1 119 ? -30.587 28.611  -13.480 1.00 30.92  ? 119 GLY B N      1 
ATOM   9102  C CA     . GLY B 1 119 ? -29.150 28.432  -13.416 1.00 32.93  ? 119 GLY B CA     1 
ATOM   9103  C C      . GLY B 1 119 ? -28.368 29.652  -13.842 1.00 30.72  ? 119 GLY B C      1 
ATOM   9104  O O      . GLY B 1 119 ? -28.919 30.614  -14.404 1.00 26.95  ? 119 GLY B O      1 
ATOM   9105  H H      . GLY B 1 119 ? -30.848 29.191  -14.059 1.00 37.10  ? 119 GLY B H      1 
ATOM   9106  H HA2    . GLY B 1 119 ? -28.892 28.218  -12.506 1.00 39.51  ? 119 GLY B HA2    1 
ATOM   9107  H HA3    . GLY B 1 119 ? -28.894 27.692  -13.988 1.00 39.51  ? 119 GLY B HA3    1 
ATOM   9108  N N      . ASN B 1 120 ? -27.071 29.612  -13.558 1.00 24.44  ? 120 ASN B N      1 
ATOM   9109  C CA     . ASN B 1 120 ? -26.166 30.664  -13.994 1.00 22.73  ? 120 ASN B CA     1 
ATOM   9110  C C      . ASN B 1 120 ? -25.763 30.401  -15.441 1.00 27.34  ? 120 ASN B C      1 
ATOM   9111  O O      . ASN B 1 120 ? -24.753 29.755  -15.714 1.00 27.89  ? 120 ASN B O      1 
ATOM   9112  C CB     . ASN B 1 120 ? -24.944 30.759  -13.076 1.00 23.92  ? 120 ASN B CB     1 
ATOM   9113  C CG     . ASN B 1 120 ? -24.299 29.406  -12.792 1.00 22.24  ? 120 ASN B CG     1 
ATOM   9114  O OD1    . ASN B 1 120 ? -24.898 28.349  -13.008 1.00 22.20  ? 120 ASN B OD1    1 
ATOM   9115  N ND2    . ASN B 1 120 ? -23.074 29.442  -12.277 1.00 20.60  ? 120 ASN B ND2    1 
ATOM   9116  H H      . ASN B 1 120 ? -26.695 28.981  -13.112 1.00 29.32  ? 120 ASN B H      1 
ATOM   9117  H HA     . ASN B 1 120 ? -26.628 31.516  -13.961 1.00 27.28  ? 120 ASN B HA     1 
ATOM   9118  H HB2    . ASN B 1 120 ? -24.278 31.325  -13.497 1.00 28.71  ? 120 ASN B HB2    1 
ATOM   9119  H HB3    . ASN B 1 120 ? -25.217 31.144  -12.228 1.00 28.71  ? 120 ASN B HB3    1 
ATOM   9120  H HD21   . ASN B 1 120 ? -22.662 28.709  -12.097 1.00 24.72  ? 120 ASN B HD21   1 
ATOM   9121  H HD22   . ASN B 1 120 ? -22.694 30.198  -12.124 1.00 24.72  ? 120 ASN B HD22   1 
ATOM   9122  N N      . MET B 1 121 ? -26.586 30.911  -16.357 1.00 29.69  ? 121 MET B N      1 
ATOM   9123  C CA     . MET B 1 121 ? -26.462 30.653  -17.793 1.00 28.23  ? 121 MET B CA     1 
ATOM   9124  C C      . MET B 1 121 ? -26.649 29.160  -18.063 1.00 29.97  ? 121 MET B C      1 
ATOM   9125  O O      . MET B 1 121 ? -27.155 28.440  -17.207 1.00 27.59  ? 121 MET B O      1 
ATOM   9126  C CB     . MET B 1 121 ? -25.125 31.167  -18.328 1.00 30.39  ? 121 MET B CB     1 
ATOM   9127  C CG     . MET B 1 121 ? -25.015 32.686  -18.260 1.00 36.63  ? 121 MET B CG     1 
ATOM   9128  S SD     . MET B 1 121 ? -23.464 33.331  -18.897 1.00 32.72  ? 121 MET B SD     1 
ATOM   9129  C CE     . MET B 1 121 ? -24.059 34.666  -19.931 1.00 44.13  ? 121 MET B CE     1 
ATOM   9130  H H      . MET B 1 121 ? -27.246 31.427  -16.164 1.00 35.62  ? 121 MET B H      1 
ATOM   9131  H HA     . MET B 1 121 ? -27.164 31.138  -18.254 1.00 33.87  ? 121 MET B HA     1 
ATOM   9132  H HB2    . MET B 1 121 ? -24.393 30.789  -17.820 1.00 36.47  ? 121 MET B HB2    1 
ATOM   9133  H HB3    . MET B 1 121 ? -25.040 30.915  -19.260 1.00 36.47  ? 121 MET B HB3    1 
ATOM   9134  H HG2    . MET B 1 121 ? -25.736 33.077  -18.779 1.00 43.96  ? 121 MET B HG2    1 
ATOM   9135  H HG3    . MET B 1 121 ? -25.090 32.959  -17.333 1.00 43.96  ? 121 MET B HG3    1 
ATOM   9136  H HE1    . MET B 1 121 ? -23.306 35.068  -20.392 1.00 52.96  ? 121 MET B HE1    1 
ATOM   9137  H HE2    . MET B 1 121 ? -24.690 34.309  -20.575 1.00 52.96  ? 121 MET B HE2    1 
ATOM   9138  H HE3    . MET B 1 121 ? -24.495 35.325  -19.369 1.00 52.96  ? 121 MET B HE3    1 
ATOM   9139  N N      . TYR B 1 122 ? -26.274 28.695  -19.250 1.00 32.80  ? 122 TYR B N      1 
ATOM   9140  C CA     . TYR B 1 122 ? -26.591 27.326  -19.642 1.00 34.80  ? 122 TYR B CA     1 
ATOM   9141  C C      . TYR B 1 122 ? -25.603 26.751  -20.643 1.00 31.84  ? 122 TYR B C      1 
ATOM   9142  O O      . TYR B 1 122 ? -24.808 27.479  -21.244 1.00 28.42  ? 122 TYR B O      1 
ATOM   9143  C CB     . TYR B 1 122 ? -27.995 27.267  -20.251 1.00 30.80  ? 122 TYR B CB     1 
ATOM   9144  C CG     . TYR B 1 122 ? -28.072 27.949  -21.598 1.00 33.71  ? 122 TYR B CG     1 
ATOM   9145  C CD1    . TYR B 1 122 ? -28.200 29.330  -21.692 1.00 34.45  ? 122 TYR B CD1    1 
ATOM   9146  C CD2    . TYR B 1 122 ? -27.994 27.215  -22.778 1.00 33.39  ? 122 TYR B CD2    1 
ATOM   9147  C CE1    . TYR B 1 122 ? -28.261 29.963  -22.922 1.00 35.25  ? 122 TYR B CE1    1 
ATOM   9148  C CE2    . TYR B 1 122 ? -28.051 27.841  -24.016 1.00 38.83  ? 122 TYR B CE2    1 
ATOM   9149  C CZ     . TYR B 1 122 ? -28.187 29.214  -24.081 1.00 40.90  ? 122 TYR B CZ     1 
ATOM   9150  O OH     . TYR B 1 122 ? -28.248 29.844  -25.308 1.00 40.43  ? 122 TYR B OH     1 
ATOM   9151  H H      . TYR B 1 122 ? -25.842 29.143  -19.842 1.00 39.36  ? 122 TYR B H      1 
ATOM   9152  H HA     . TYR B 1 122 ? -26.579 26.754  -18.859 1.00 41.75  ? 122 TYR B HA     1 
ATOM   9153  H HB2    . TYR B 1 122 ? -28.250 26.339  -20.370 1.00 36.96  ? 122 TYR B HB2    1 
ATOM   9154  H HB3    . TYR B 1 122 ? -28.618 27.709  -19.654 1.00 36.96  ? 122 TYR B HB3    1 
ATOM   9155  H HD1    . TYR B 1 122 ? -28.251 29.838  -20.914 1.00 41.34  ? 122 TYR B HD1    1 
ATOM   9156  H HD2    . TYR B 1 122 ? -27.903 26.290  -22.737 1.00 40.06  ? 122 TYR B HD2    1 
ATOM   9157  H HE1    . TYR B 1 122 ? -28.351 30.887  -22.968 1.00 42.29  ? 122 TYR B HE1    1 
ATOM   9158  H HE2    . TYR B 1 122 ? -28.003 27.338  -24.797 1.00 46.60  ? 122 TYR B HE2    1 
ATOM   9159  H HH     . TYR B 1 122 ? -28.192 29.277  -25.925 1.00 48.51  ? 122 TYR B HH     1 
ATOM   9160  N N      . PHE B 1 123 ? -25.676 25.431  -20.803 1.00 28.42  ? 123 PHE B N      1 
ATOM   9161  C CA     . PHE B 1 123 ? -24.996 24.722  -21.880 1.00 32.46  ? 123 PHE B CA     1 
ATOM   9162  C C      . PHE B 1 123 ? -26.036 23.971  -22.700 1.00 30.26  ? 123 PHE B C      1 
ATOM   9163  O O      . PHE B 1 123 ? -27.057 23.529  -22.174 1.00 25.84  ? 123 PHE B O      1 
ATOM   9164  C CB     . PHE B 1 123 ? -23.937 23.756  -21.340 1.00 30.59  ? 123 PHE B CB     1 
ATOM   9165  C CG     . PHE B 1 123 ? -23.163 23.044  -22.421 1.00 32.42  ? 123 PHE B CG     1 
ATOM   9166  C CD1    . PHE B 1 123 ? -22.267 23.733  -23.221 1.00 35.30  ? 123 PHE B CD1    1 
ATOM   9167  C CD2    . PHE B 1 123 ? -23.334 21.687  -22.636 1.00 28.94  ? 123 PHE B CD2    1 
ATOM   9168  C CE1    . PHE B 1 123 ? -21.557 23.079  -24.220 1.00 33.98  ? 123 PHE B CE1    1 
ATOM   9169  C CE2    . PHE B 1 123 ? -22.627 21.028  -23.629 1.00 25.65  ? 123 PHE B CE2    1 
ATOM   9170  C CZ     . PHE B 1 123 ? -21.741 21.722  -24.422 1.00 33.45  ? 123 PHE B CZ     1 
ATOM   9171  H H      . PHE B 1 123 ? -26.126 24.913  -20.285 1.00 34.10  ? 123 PHE B H      1 
ATOM   9172  H HA     . PHE B 1 123 ? -24.555 25.358  -22.464 1.00 38.95  ? 123 PHE B HA     1 
ATOM   9173  H HB2    . PHE B 1 123 ? -23.304 24.255  -20.801 1.00 36.71  ? 123 PHE B HB2    1 
ATOM   9174  H HB3    . PHE B 1 123 ? -24.375 23.083  -20.796 1.00 36.71  ? 123 PHE B HB3    1 
ATOM   9175  H HD1    . PHE B 1 123 ? -22.142 24.645  -23.091 1.00 42.36  ? 123 PHE B HD1    1 
ATOM   9176  H HD2    . PHE B 1 123 ? -23.932 21.211  -22.106 1.00 34.73  ? 123 PHE B HD2    1 
ATOM   9177  H HE1    . PHE B 1 123 ? -20.958 23.552  -24.751 1.00 40.77  ? 123 PHE B HE1    1 
ATOM   9178  H HE2    . PHE B 1 123 ? -22.753 20.116  -23.762 1.00 30.78  ? 123 PHE B HE2    1 
ATOM   9179  H HZ     . PHE B 1 123 ? -21.265 21.280  -25.088 1.00 40.15  ? 123 PHE B HZ     1 
ATOM   9180  N N      . THR B 1 124 ? -25.776 23.832  -23.995 1.00 28.97  ? 124 THR B N      1 
ATOM   9181  C CA     . THR B 1 124 ? -26.778 23.313  -24.918 1.00 29.33  ? 124 THR B CA     1 
ATOM   9182  C C      . THR B 1 124 ? -27.383 21.971  -24.491 1.00 30.09  ? 124 THR B C      1 
ATOM   9183  O O      . THR B 1 124 ? -28.603 21.830  -24.470 1.00 26.41  ? 124 THR B O      1 
ATOM   9184  C CB     . THR B 1 124 ? -26.178 23.176  -26.329 1.00 33.07  ? 124 THR B CB     1 
ATOM   9185  O OG1    . THR B 1 124 ? -25.811 24.480  -26.805 1.00 34.55  ? 124 THR B OG1    1 
ATOM   9186  C CG2    . THR B 1 124 ? -27.182 22.550  -27.297 1.00 33.22  ? 124 THR B CG2    1 
ATOM   9187  H H      . THR B 1 124 ? -25.026 24.031  -24.365 1.00 34.76  ? 124 THR B H      1 
ATOM   9188  H HA     . THR B 1 124 ? -27.504 23.954  -24.972 1.00 35.20  ? 124 THR B HA     1 
ATOM   9189  H HB     . THR B 1 124 ? -25.391 22.611  -26.293 1.00 39.69  ? 124 THR B HB     1 
ATOM   9190  H HG1    . THR B 1 124 ? -25.482 24.422  -27.576 1.00 41.47  ? 124 THR B HG1    1 
ATOM   9191  H HG21   . THR B 1 124 ? -26.909 22.723  -28.212 1.00 39.86  ? 124 THR B HG21   1 
ATOM   9192  H HG22   . THR B 1 124 ? -27.227 21.591  -27.159 1.00 39.86  ? 124 THR B HG22   1 
ATOM   9193  H HG23   . THR B 1 124 ? -28.062 22.933  -27.155 1.00 39.86  ? 124 THR B HG23   1 
ATOM   9194  N N      . THR B 1 125 ? -26.555 20.986  -24.148 1.00 26.33  ? 125 THR B N      1 
ATOM   9195  C CA     . THR B 1 125 ? -27.089 19.655  -23.865 1.00 27.97  ? 125 THR B CA     1 
ATOM   9196  C C      . THR B 1 125 ? -27.832 19.662  -22.538 1.00 24.90  ? 125 THR B C      1 
ATOM   9197  O O      . THR B 1 125 ? -28.871 19.020  -22.392 1.00 26.53  ? 125 THR B O      1 
ATOM   9198  C CB     . THR B 1 125 ? -25.986 18.575  -23.829 1.00 25.35  ? 125 THR B CB     1 
ATOM   9199  O OG1    . THR B 1 125 ? -25.032 18.896  -22.811 1.00 24.50  ? 125 THR B OG1    1 
ATOM   9200  C CG2    . THR B 1 125 ? -25.290 18.481  -25.179 1.00 26.08  ? 125 THR B CG2    1 
ATOM   9201  H H      . THR B 1 125 ? -25.701 21.058  -24.073 1.00 31.60  ? 125 THR B H      1 
ATOM   9202  H HA     . THR B 1 125 ? -27.720 19.413  -24.561 1.00 33.56  ? 125 THR B HA     1 
ATOM   9203  H HB     . THR B 1 125 ? -26.387 17.714  -23.632 1.00 30.41  ? 125 THR B HB     1 
ATOM   9204  H HG1    . THR B 1 125 ? -25.396 18.864  -22.055 1.00 29.40  ? 125 THR B HG1    1 
ATOM   9205  H HG21   . THR B 1 125 ? -24.618 17.782  -25.157 1.00 31.29  ? 125 THR B HG21   1 
ATOM   9206  H HG22   . THR B 1 125 ? -25.937 18.275  -25.872 1.00 31.29  ? 125 THR B HG22   1 
ATOM   9207  H HG23   . THR B 1 125 ? -24.860 19.325  -25.390 1.00 31.29  ? 125 THR B HG23   1 
ATOM   9208  N N      . THR B 1 126 ? -27.289 20.396  -21.577 1.00 24.45  ? 126 THR B N      1 
ATOM   9209  C CA     . THR B 1 126 ? -27.885 20.491  -20.252 1.00 28.82  ? 126 THR B CA     1 
ATOM   9210  C C      . THR B 1 126 ? -29.298 21.055  -20.358 1.00 27.55  ? 126 THR B C      1 
ATOM   9211  O O      . THR B 1 126 ? -30.253 20.493  -19.822 1.00 30.46  ? 126 THR B O      1 
ATOM   9212  C CB     . THR B 1 126 ? -27.047 21.385  -19.341 1.00 30.45  ? 126 THR B CB     1 
ATOM   9213  O OG1    . THR B 1 126 ? -25.656 21.138  -19.580 1.00 30.57  ? 126 THR B OG1    1 
ATOM   9214  C CG2    . THR B 1 126 ? -27.380 21.130  -17.873 1.00 35.22  ? 126 THR B CG2    1 
ATOM   9215  H H      . THR B 1 126 ? -26.567 20.854  -21.668 1.00 29.34  ? 126 THR B H      1 
ATOM   9216  H HA     . THR B 1 126 ? -27.935 19.607  -19.855 1.00 34.59  ? 126 THR B HA     1 
ATOM   9217  H HB     . THR B 1 126 ? -27.241 22.309  -19.547 1.00 36.54  ? 126 THR B HB     1 
ATOM   9218  H HG1    . THR B 1 126 ? -25.443 20.384  -19.282 1.00 36.68  ? 126 THR B HG1    1 
ATOM   9219  H HG21   . THR B 1 126 ? -26.838 21.701  -17.306 1.00 42.27  ? 126 THR B HG21   1 
ATOM   9220  H HG22   . THR B 1 126 ? -28.317 21.320  -17.708 1.00 42.27  ? 126 THR B HG22   1 
ATOM   9221  H HG23   . THR B 1 126 ? -27.202 20.203  -17.649 1.00 42.27  ? 126 THR B HG23   1 
ATOM   9222  N N      . ARG B 1 127 ? -29.417 22.160  -21.079 1.00 27.07  ? 127 ARG B N      1 
ATOM   9223  C CA     . ARG B 1 127 ? -30.695 22.832  -21.241 1.00 29.17  ? 127 ARG B CA     1 
ATOM   9224  C C      . ARG B 1 127 ? -31.671 21.980  -22.043 1.00 28.99  ? 127 ARG B C      1 
ATOM   9225  O O      . ARG B 1 127 ? -32.863 21.949  -21.738 1.00 29.59  ? 127 ARG B O      1 
ATOM   9226  C CB     . ARG B 1 127 ? -30.496 24.185  -21.914 1.00 28.58  ? 127 ARG B CB     1 
ATOM   9227  C CG     . ARG B 1 127 ? -31.788 24.949  -22.119 1.00 35.53  ? 127 ARG B CG     1 
ATOM   9228  C CD     . ARG B 1 127 ? -31.519 26.398  -22.477 1.00 36.68  ? 127 ARG B CD     1 
ATOM   9229  N NE     . ARG B 1 127 ? -32.759 27.143  -22.658 1.00 41.67  ? 127 ARG B NE     1 
ATOM   9230  C CZ     . ARG B 1 127 ? -32.824 28.462  -22.820 1.00 48.80  ? 127 ARG B CZ     1 
ATOM   9231  N NH1    . ARG B 1 127 ? -31.717 29.194  -22.820 1.00 43.25  ? 127 ARG B NH1    1 
ATOM   9232  N NH2    . ARG B 1 127 ? -34.002 29.051  -22.974 1.00 57.19  ? 127 ARG B NH2    1 
ATOM   9233  H H      . ARG B 1 127 ? -28.765 22.544  -21.488 1.00 32.49  ? 127 ARG B H      1 
ATOM   9234  H HA     . ARG B 1 127 ? -31.083 22.987  -20.366 1.00 35.00  ? 127 ARG B HA     1 
ATOM   9235  H HB2    . ARG B 1 127 ? -29.913 24.728  -21.361 1.00 34.29  ? 127 ARG B HB2    1 
ATOM   9236  H HB3    . ARG B 1 127 ? -30.090 24.046  -22.784 1.00 34.29  ? 127 ARG B HB3    1 
ATOM   9237  H HG2    . ARG B 1 127 ? -32.289 24.545  -22.845 1.00 42.64  ? 127 ARG B HG2    1 
ATOM   9238  H HG3    . ARG B 1 127 ? -32.307 24.929  -21.300 1.00 42.64  ? 127 ARG B HG3    1 
ATOM   9239  H HD2    . ARG B 1 127 ? -31.015 26.816  -21.761 1.00 44.02  ? 127 ARG B HD2    1 
ATOM   9240  H HD3    . ARG B 1 127 ? -31.018 26.435  -23.307 1.00 44.02  ? 127 ARG B HD3    1 
ATOM   9241  H HE     . ARG B 1 127 ? -33.497 26.722  -22.531 1.00 50.00  ? 127 ARG B HE     1 
ATOM   9242  H HH11   . ARG B 1 127 ? -30.950 28.820  -22.719 1.00 51.90  ? 127 ARG B HH11   1 
ATOM   9243  H HH12   . ARG B 1 127 ? -31.767 30.046  -22.924 1.00 51.90  ? 127 ARG B HH12   1 
ATOM   9244  H HH21   . ARG B 1 127 ? -34.722 28.580  -22.974 1.00 68.63  ? 127 ARG B HH21   1 
ATOM   9245  H HH22   . ARG B 1 127 ? -34.046 29.903  -23.079 1.00 68.63  ? 127 ARG B HH22   1 
ATOM   9246  N N      . TYR B 1 128 ? -31.175 21.284  -23.066 1.00 28.66  ? 128 TYR B N      1 
ATOM   9247  C CA     . TYR B 1 128 ? -32.037 20.399  -23.845 1.00 29.35  ? 128 TYR B CA     1 
ATOM   9248  C C      . TYR B 1 128 ? -32.754 19.400  -22.946 1.00 28.98  ? 128 TYR B C      1 
ATOM   9249  O O      . TYR B 1 128 ? -33.968 19.235  -23.032 1.00 31.83  ? 128 TYR B O      1 
ATOM   9250  C CB     . TYR B 1 128 ? -31.247 19.636  -24.909 1.00 32.57  ? 128 TYR B CB     1 
ATOM   9251  C CG     . TYR B 1 128 ? -32.083 18.572  -25.590 1.00 29.55  ? 128 TYR B CG     1 
ATOM   9252  C CD1    . TYR B 1 128 ? -32.226 17.308  -25.029 1.00 34.32  ? 128 TYR B CD1    1 
ATOM   9253  C CD2    . TYR B 1 128 ? -32.748 18.836  -26.779 1.00 34.82  ? 128 TYR B CD2    1 
ATOM   9254  C CE1    . TYR B 1 128 ? -33.009 16.343  -25.624 1.00 37.56  ? 128 TYR B CE1    1 
ATOM   9255  C CE2    . TYR B 1 128 ? -33.526 17.862  -27.395 1.00 34.53  ? 128 TYR B CE2    1 
ATOM   9256  C CZ     . TYR B 1 128 ? -33.643 16.616  -26.813 1.00 37.92  ? 128 TYR B CZ     1 
ATOM   9257  O OH     . TYR B 1 128 ? -34.406 15.635  -27.403 1.00 45.34  ? 128 TYR B OH     1 
ATOM   9258  H H      . TYR B 1 128 ? -30.355 21.306  -23.326 1.00 34.39  ? 128 TYR B H      1 
ATOM   9259  H HA     . TYR B 1 128 ? -32.710 20.932  -24.297 1.00 35.22  ? 128 TYR B HA     1 
ATOM   9260  H HB2    . TYR B 1 128 ? -30.942 20.260  -25.587 1.00 39.08  ? 128 TYR B HB2    1 
ATOM   9261  H HB3    . TYR B 1 128 ? -30.488 19.201  -24.490 1.00 39.08  ? 128 TYR B HB3    1 
ATOM   9262  H HD1    . TYR B 1 128 ? -31.798 17.115  -24.226 1.00 41.18  ? 128 TYR B HD1    1 
ATOM   9263  H HD2    . TYR B 1 128 ? -32.667 19.675  -27.173 1.00 41.78  ? 128 TYR B HD2    1 
ATOM   9264  H HE1    . TYR B 1 128 ? -33.084 15.500  -25.238 1.00 45.07  ? 128 TYR B HE1    1 
ATOM   9265  H HE2    . TYR B 1 128 ? -33.962 18.048  -28.195 1.00 41.43  ? 128 TYR B HE2    1 
ATOM   9266  H HH     . TYR B 1 128 ? -34.739 15.922  -28.119 1.00 54.41  ? 128 TYR B HH     1 
ATOM   9267  N N      . HIS B 1 129 ? -32.002 18.721  -22.089 1.00 29.74  ? 129 HIS B N      1 
ATOM   9268  C CA     . HIS B 1 129 ? -32.578 17.665  -21.268 1.00 31.56  ? 129 HIS B CA     1 
ATOM   9269  C C      . HIS B 1 129 ? -33.545 18.229  -20.238 1.00 29.86  ? 129 HIS B C      1 
ATOM   9270  O O      . HIS B 1 129 ? -34.544 17.598  -19.913 1.00 29.57  ? 129 HIS B O      1 
ATOM   9271  C CB     . HIS B 1 129 ? -31.471 16.858  -20.594 1.00 30.48  ? 129 HIS B CB     1 
ATOM   9272  C CG     . HIS B 1 129 ? -30.694 16.015  -21.558 1.00 33.81  ? 129 HIS B CG     1 
ATOM   9273  N ND1    . HIS B 1 129 ? -31.275 14.994  -22.279 1.00 28.80  ? 129 HIS B ND1    1 
ATOM   9274  C CD2    . HIS B 1 129 ? -29.397 16.060  -21.944 1.00 28.80  ? 129 HIS B CD2    1 
ATOM   9275  C CE1    . HIS B 1 129 ? -30.366 14.438  -23.059 1.00 31.19  ? 129 HIS B CE1    1 
ATOM   9276  N NE2    . HIS B 1 129 ? -29.218 15.067  -22.875 1.00 28.06  ? 129 HIS B NE2    1 
ATOM   9277  H H      . HIS B 1 129 ? -31.161 18.851  -21.964 1.00 35.68  ? 129 HIS B H      1 
ATOM   9278  H HA     . HIS B 1 129 ? -33.076 17.061  -21.841 1.00 37.87  ? 129 HIS B HA     1 
ATOM   9279  H HB2    . HIS B 1 129 ? -30.852 17.469  -20.164 1.00 36.57  ? 129 HIS B HB2    1 
ATOM   9280  H HB3    . HIS B 1 129 ? -31.868 16.269  -19.933 1.00 36.57  ? 129 HIS B HB3    1 
ATOM   9281  H HD2    . HIS B 1 129 ? -28.748 16.650  -21.634 1.00 34.56  ? 129 HIS B HD2    1 
ATOM   9282  H HE1    . HIS B 1 129 ? -30.509 13.724  -23.638 1.00 37.43  ? 129 HIS B HE1    1 
ATOM   9283  H HE2    . HIS B 1 129 ? -28.478 14.881  -23.271 1.00 33.67  ? 129 HIS B HE2    1 
ATOM   9284  N N      . GLN B 1 130 ? -33.254 19.426  -19.748 1.00 29.85  ? 130 GLN B N      1 
ATOM   9285  C CA     . GLN B 1 130 ? -34.161 20.119  -18.836 1.00 29.82  ? 130 GLN B CA     1 
ATOM   9286  C C      . GLN B 1 130 ? -35.487 20.415  -19.528 1.00 31.69  ? 130 GLN B C      1 
ATOM   9287  O O      . GLN B 1 130 ? -36.557 20.095  -19.008 1.00 32.03  ? 130 GLN B O      1 
ATOM   9288  C CB     . GLN B 1 130 ? -33.521 21.412  -18.328 1.00 27.52  ? 130 GLN B CB     1 
ATOM   9289  C CG     . GLN B 1 130 ? -32.335 21.176  -17.406 1.00 24.79  ? 130 GLN B CG     1 
ATOM   9290  C CD     . GLN B 1 130 ? -31.520 22.429  -17.146 1.00 24.96  ? 130 GLN B CD     1 
ATOM   9291  O OE1    . GLN B 1 130 ? -31.824 23.506  -17.659 1.00 29.44  ? 130 GLN B OE1    1 
ATOM   9292  N NE2    . GLN B 1 130 ? -30.476 22.291  -16.342 1.00 29.10  ? 130 GLN B NE2    1 
ATOM   9293  H H      . GLN B 1 130 ? -32.535 19.863  -19.927 1.00 35.82  ? 130 GLN B H      1 
ATOM   9294  H HA     . GLN B 1 130 ? -34.339 19.549  -18.072 1.00 35.78  ? 130 GLN B HA     1 
ATOM   9295  H HB2    . GLN B 1 130 ? -33.210 21.926  -19.090 1.00 33.03  ? 130 GLN B HB2    1 
ATOM   9296  H HB3    . GLN B 1 130 ? -34.185 21.919  -17.836 1.00 33.03  ? 130 GLN B HB3    1 
ATOM   9297  H HG2    . GLN B 1 130 ? -32.662 20.853  -16.552 1.00 29.75  ? 130 GLN B HG2    1 
ATOM   9298  H HG3    . GLN B 1 130 ? -31.750 20.514  -17.805 1.00 29.75  ? 130 GLN B HG3    1 
ATOM   9299  H HE21   . GLN B 1 130 ? -30.291 21.521  -16.006 1.00 34.92  ? 130 GLN B HE21   1 
ATOM   9300  H HE22   . GLN B 1 130 ? -29.984 22.971  -16.156 1.00 34.92  ? 130 GLN B HE22   1 
ATOM   9301  N N      . GLU B 1 131 ? -35.409 20.996  -20.719 1.00 32.94  ? 131 GLU B N      1 
ATOM   9302  C CA     . GLU B 1 131 ? -36.602 21.378  -21.467 1.00 33.33  ? 131 GLU B CA     1 
ATOM   9303  C C      . GLU B 1 131 ? -37.348 20.154  -22.003 1.00 38.41  ? 131 GLU B C      1 
ATOM   9304  O O      . GLU B 1 131 ? -38.579 20.132  -22.024 1.00 37.76  ? 131 GLU B O      1 
ATOM   9305  C CB     . GLU B 1 131 ? -36.225 22.319  -22.610 1.00 31.87  ? 131 GLU B CB     1 
ATOM   9306  C CG     . GLU B 1 131 ? -35.748 23.685  -22.131 1.00 38.28  ? 131 GLU B CG     1 
ATOM   9307  C CD     . GLU B 1 131 ? -35.276 24.586  -23.260 1.00 43.93  ? 131 GLU B CD     1 
ATOM   9308  O OE1    . GLU B 1 131 ? -34.937 25.758  -22.982 1.00 37.43  ? 131 GLU B OE1    1 
ATOM   9309  O OE2    . GLU B 1 131 ? -35.238 24.122  -24.420 1.00 48.84  ? 131 GLU B OE2    1 
ATOM   9310  H H      . GLU B 1 131 ? -34.671 21.182  -21.120 1.00 39.52  ? 131 GLU B H      1 
ATOM   9311  H HA     . GLU B 1 131 ? -37.203 21.854  -20.875 1.00 40.00  ? 131 GLU B HA     1 
ATOM   9312  H HB2    . GLU B 1 131 ? -35.508 21.915  -23.124 1.00 38.25  ? 131 GLU B HB2    1 
ATOM   9313  H HB3    . GLU B 1 131 ? -37.002 22.455  -23.175 1.00 38.25  ? 131 GLU B HB3    1 
ATOM   9314  H HG2    . GLU B 1 131 ? -36.480 24.133  -21.678 1.00 45.93  ? 131 GLU B HG2    1 
ATOM   9315  H HG3    . GLU B 1 131 ? -35.007 23.562  -21.518 1.00 45.93  ? 131 GLU B HG3    1 
ATOM   9316  N N      . LYS B 1 132 ? -36.601 19.135  -22.416 1.00 32.98  ? 132 LYS B N      1 
ATOM   9317  C CA     . LYS B 1 132 ? -37.191 17.896  -22.919 1.00 34.68  ? 132 LYS B CA     1 
ATOM   9318  C C      . LYS B 1 132 ? -38.101 17.253  -21.873 1.00 35.46  ? 132 LYS B C      1 
ATOM   9319  O O      . LYS B 1 132 ? -39.100 16.614  -22.211 1.00 35.81  ? 132 LYS B O      1 
ATOM   9320  C CB     . LYS B 1 132 ? -36.084 16.917  -23.332 1.00 36.10  ? 132 LYS B CB     1 
ATOM   9321  C CG     . LYS B 1 132 ? -36.562 15.545  -23.804 1.00 40.32  ? 132 LYS B CG     1 
ATOM   9322  C CD     . LYS B 1 132 ? -37.352 15.643  -25.095 1.00 52.94  ? 132 LYS B CD     1 
ATOM   9323  C CE     . LYS B 1 132 ? -37.715 14.268  -25.632 1.00 53.29  ? 132 LYS B CE     1 
ATOM   9324  N NZ     . LYS B 1 132 ? -38.526 14.363  -26.879 1.00 65.81  ? 132 LYS B NZ     1 
ATOM   9325  H H      . LYS B 1 132 ? -35.741 19.135  -22.415 1.00 39.58  ? 132 LYS B H      1 
ATOM   9326  H HA     . LYS B 1 132 ? -37.726 18.095  -23.703 1.00 41.62  ? 132 LYS B HA     1 
ATOM   9327  H HB2    . LYS B 1 132 ? -35.578 17.314  -24.058 1.00 43.32  ? 132 LYS B HB2    1 
ATOM   9328  H HB3    . LYS B 1 132 ? -35.500 16.775  -22.571 1.00 43.32  ? 132 LYS B HB3    1 
ATOM   9329  H HG2    . LYS B 1 132 ? -35.790 14.980  -23.967 1.00 48.38  ? 132 LYS B HG2    1 
ATOM   9330  H HG3    . LYS B 1 132 ? -37.129 15.144  -23.128 1.00 48.38  ? 132 LYS B HG3    1 
ATOM   9331  H HD2    . LYS B 1 132 ? -38.174 16.132  -24.931 1.00 63.53  ? 132 LYS B HD2    1 
ATOM   9332  H HD3    . LYS B 1 132 ? -36.817 16.099  -25.764 1.00 63.53  ? 132 LYS B HD3    1 
ATOM   9333  H HE2    . LYS B 1 132 ? -36.902 13.779  -25.835 1.00 63.95  ? 132 LYS B HE2    1 
ATOM   9334  H HE3    . LYS B 1 132 ? -38.236 13.792  -24.966 1.00 63.95  ? 132 LYS B HE3    1 
ATOM   9335  H HZ1    . LYS B 1 132 ? -38.726 13.548  -27.174 1.00 78.98  ? 132 LYS B HZ1    1 
ATOM   9336  H HZ2    . LYS B 1 132 ? -39.281 14.806  -26.718 1.00 78.98  ? 132 LYS B HZ2    1 
ATOM   9337  H HZ3    . LYS B 1 132 ? -38.067 14.794  -27.508 1.00 78.98  ? 132 LYS B HZ3    1 
ATOM   9338  N N      . ASN B 1 133 ? -37.747 17.428  -20.604 1.00 35.10  ? 133 ASN B N      1 
ATOM   9339  C CA     . ASN B 1 133 ? -38.508 16.857  -19.499 1.00 36.34  ? 133 ASN B CA     1 
ATOM   9340  C C      . ASN B 1 133 ? -39.543 17.818  -18.901 1.00 35.27  ? 133 ASN B C      1 
ATOM   9341  O O      . ASN B 1 133 ? -40.075 17.566  -17.821 1.00 41.03  ? 133 ASN B O      1 
ATOM   9342  C CB     . ASN B 1 133 ? -37.541 16.379  -18.416 1.00 35.33  ? 133 ASN B CB     1 
ATOM   9343  C CG     . ASN B 1 133 ? -36.864 15.074  -18.787 1.00 38.32  ? 133 ASN B CG     1 
ATOM   9344  O OD1    . ASN B 1 133 ? -37.438 13.999  -18.613 1.00 40.17  ? 133 ASN B OD1    1 
ATOM   9345  N ND2    . ASN B 1 133 ? -35.648 15.162  -19.315 1.00 34.58  ? 133 ASN B ND2    1 
ATOM   9346  H H      . ASN B 1 133 ? -37.060 17.880  -20.353 1.00 42.12  ? 133 ASN B H      1 
ATOM   9347  H HA     . ASN B 1 133 ? -38.988 16.077  -19.818 1.00 43.60  ? 133 ASN B HA     1 
ATOM   9348  H HB2    . ASN B 1 133 ? -36.852 17.050  -18.288 1.00 42.40  ? 133 ASN B HB2    1 
ATOM   9349  H HB3    . ASN B 1 133 ? -38.025 16.237  -17.588 1.00 42.40  ? 133 ASN B HB3    1 
ATOM   9350  H HD21   . ASN B 1 133 ? -35.225 14.448  -19.542 1.00 41.50  ? 133 ASN B HD21   1 
ATOM   9351  H HD22   . ASN B 1 133 ? -35.284 15.932  -19.429 1.00 41.50  ? 133 ASN B HD22   1 
ATOM   9352  N N      . GLY B 1 134 ? -39.817 18.913  -19.608 1.00 35.43  ? 134 GLY B N      1 
ATOM   9353  C CA     . GLY B 1 134 ? -40.938 19.783  -19.290 1.00 38.40  ? 134 GLY B CA     1 
ATOM   9354  C C      . GLY B 1 134 ? -40.605 21.084  -18.583 1.00 45.29  ? 134 GLY B C      1 
ATOM   9355  O O      . GLY B 1 134 ? -41.516 21.822  -18.195 1.00 44.19  ? 134 GLY B O      1 
ATOM   9356  H H      . GLY B 1 134 ? -39.359 19.176  -20.287 1.00 42.51  ? 134 GLY B H      1 
ATOM   9357  H HA2    . GLY B 1 134 ? -41.392 20.011  -20.117 1.00 46.08  ? 134 GLY B HA2    1 
ATOM   9358  H HA3    . GLY B 1 134 ? -41.568 19.298  -18.736 1.00 46.08  ? 134 GLY B HA3    1 
ATOM   9359  N N      . ALA B 1 135 ? -39.319 21.383  -18.417 1.00 38.08  ? 135 ALA B N      1 
ATOM   9360  C CA     . ALA B 1 135 ? -38.922 22.563  -17.656 1.00 34.82  ? 135 ALA B CA     1 
ATOM   9361  C C      . ALA B 1 135 ? -38.742 23.794  -18.525 1.00 34.58  ? 135 ALA B C      1 
ATOM   9362  O O      . ALA B 1 135 ? -38.383 23.712  -19.702 1.00 35.61  ? 135 ALA B O      1 
ATOM   9363  C CB     . ALA B 1 135 ? -37.643 22.294  -16.887 1.00 35.26  ? 135 ALA B CB     1 
ATOM   9364  H H      . ALA B 1 135 ? -38.663 20.924  -18.731 1.00 45.70  ? 135 ALA B H      1 
ATOM   9365  H HA     . ALA B 1 135 ? -39.611 22.759  -17.006 1.00 41.78  ? 135 ALA B HA     1 
ATOM   9366  H HB1    . ALA B 1 135 ? -37.396 23.096  -16.400 1.00 42.31  ? 135 ALA B HB1    1 
ATOM   9367  H HB2    . ALA B 1 135 ? -37.793 21.566  -16.266 1.00 42.31  ? 135 ALA B HB2    1 
ATOM   9368  H HB3    . ALA B 1 135 ? -36.940 22.060  -17.512 1.00 42.31  ? 135 ALA B HB3    1 
ATOM   9369  N N      . THR B 1 136 ? -39.007 24.942  -17.915 1.00 33.20  ? 136 THR B N      1 
ATOM   9370  C CA     . THR B 1 136 ? -38.669 26.232  -18.486 1.00 35.67  ? 136 THR B CA     1 
ATOM   9371  C C      . THR B 1 136 ? -37.384 26.701  -17.827 1.00 30.57  ? 136 THR B C      1 
ATOM   9372  O O      . THR B 1 136 ? -37.284 26.708  -16.604 1.00 30.71  ? 136 THR B O      1 
ATOM   9373  C CB     . THR B 1 136 ? -39.792 27.259  -18.258 1.00 34.32  ? 136 THR B CB     1 
ATOM   9374  O OG1    . THR B 1 136 ? -40.981 26.809  -18.918 1.00 38.90  ? 136 THR B OG1    1 
ATOM   9375  C CG2    . THR B 1 136 ? -39.402 28.632  -18.794 1.00 36.00  ? 136 THR B CG2    1 
ATOM   9376  H H      . THR B 1 136 ? -39.393 24.998  -17.148 1.00 39.84  ? 136 THR B H      1 
ATOM   9377  H HA     . THR B 1 136 ? -38.517 26.148  -19.440 1.00 42.81  ? 136 THR B HA     1 
ATOM   9378  H HB     . THR B 1 136 ? -39.965 27.338  -17.308 1.00 41.18  ? 136 THR B HB     1 
ATOM   9379  H HG1    . THR B 1 136 ? -41.602 27.362  -18.800 1.00 46.68  ? 136 THR B HG1    1 
ATOM   9380  H HG21   . THR B 1 136 ? -40.178 29.214  -18.806 1.00 43.20  ? 136 THR B HG21   1 
ATOM   9381  H HG22   . THR B 1 136 ? -38.720 29.030  -18.230 1.00 43.20  ? 136 THR B HG22   1 
ATOM   9382  H HG23   . THR B 1 136 ? -39.058 28.550  -19.697 1.00 43.20  ? 136 THR B HG23   1 
ATOM   9383  N N      . PHE B 1 137 ? -36.400 27.089  -18.628 1.00 34.20  ? 137 PHE B N      1 
ATOM   9384  C CA     . PHE B 1 137 ? -35.125 27.516  -18.071 1.00 35.55  ? 137 PHE B CA     1 
ATOM   9385  C C      . PHE B 1 137 ? -35.121 29.012  -17.798 1.00 33.25  ? 137 PHE B C      1 
ATOM   9386  O O      . PHE B 1 137 ? -35.481 29.804  -18.664 1.00 34.35  ? 137 PHE B O      1 
ATOM   9387  C CB     . PHE B 1 137 ? -33.961 27.164  -19.000 1.00 34.73  ? 137 PHE B CB     1 
ATOM   9388  C CG     . PHE B 1 137 ? -32.666 27.805  -18.592 1.00 33.19  ? 137 PHE B CG     1 
ATOM   9389  C CD1    . PHE B 1 137 ? -31.943 27.310  -17.518 1.00 33.97  ? 137 PHE B CD1    1 
ATOM   9390  C CD2    . PHE B 1 137 ? -32.187 28.920  -19.263 1.00 36.38  ? 137 PHE B CD2    1 
ATOM   9391  C CE1    . PHE B 1 137 ? -30.758 27.908  -17.129 1.00 34.57  ? 137 PHE B CE1    1 
ATOM   9392  C CE2    . PHE B 1 137 ? -31.003 29.521  -18.881 1.00 37.00  ? 137 PHE B CE2    1 
ATOM   9393  C CZ     . PHE B 1 137 ? -30.289 29.015  -17.809 1.00 32.87  ? 137 PHE B CZ     1 
ATOM   9394  H H      . PHE B 1 137 ? -36.444 27.114  -19.487 1.00 41.04  ? 137 PHE B H      1 
ATOM   9395  H HA     . PHE B 1 137 ? -34.973 27.055  -17.234 1.00 42.67  ? 137 PHE B HA     1 
ATOM   9396  H HB2    . PHE B 1 137 ? -33.833 26.202  -18.994 1.00 41.67  ? 137 PHE B HB2    1 
ATOM   9397  H HB3    . PHE B 1 137 ? -34.173 27.464  -19.898 1.00 41.67  ? 137 PHE B HB3    1 
ATOM   9398  H HD1    . PHE B 1 137 ? -32.257 26.567  -17.056 1.00 40.77  ? 137 PHE B HD1    1 
ATOM   9399  H HD2    . PHE B 1 137 ? -32.666 29.264  -19.982 1.00 43.65  ? 137 PHE B HD2    1 
ATOM   9400  H HE1    . PHE B 1 137 ? -30.278 27.565  -16.410 1.00 41.49  ? 137 PHE B HE1    1 
ATOM   9401  H HE2    . PHE B 1 137 ? -30.689 30.266  -19.341 1.00 44.40  ? 137 PHE B HE2    1 
ATOM   9402  H HZ     . PHE B 1 137 ? -29.490 29.416  -17.551 1.00 39.45  ? 137 PHE B HZ     1 
ATOM   9403  N N      . ILE B 1 138 ? -34.704 29.380  -16.587 1.00 31.53  ? 138 ILE B N      1 
ATOM   9404  C CA     . ILE B 1 138 ? -34.567 30.781  -16.184 1.00 28.98  ? 138 ILE B CA     1 
ATOM   9405  C C      . ILE B 1 138 ? -33.111 31.106  -15.888 1.00 27.31  ? 138 ILE B C      1 
ATOM   9406  O O      . ILE B 1 138 ? -32.499 30.483  -15.033 1.00 29.45  ? 138 ILE B O      1 
ATOM   9407  C CB     . ILE B 1 138 ? -35.402 31.101  -14.924 1.00 28.31  ? 138 ILE B CB     1 
ATOM   9408  C CG1    . ILE B 1 138 ? -36.863 30.673  -15.107 1.00 33.06  ? 138 ILE B CG1    1 
ATOM   9409  C CG2    . ILE B 1 138 ? -35.293 32.586  -14.559 1.00 31.57  ? 138 ILE B CG2    1 
ATOM   9410  C CD1    . ILE B 1 138 ? -37.551 31.286  -16.304 1.00 36.71  ? 138 ILE B CD1    1 
ATOM   9411  H H      . ILE B 1 138 ? -34.489 28.824  -15.967 1.00 37.84  ? 138 ILE B H      1 
ATOM   9412  H HA     . ILE B 1 138 ? -34.865 31.362  -16.900 1.00 34.77  ? 138 ILE B HA     1 
ATOM   9413  H HB     . ILE B 1 138 ? -35.034 30.588  -14.188 1.00 33.97  ? 138 ILE B HB     1 
ATOM   9414  H HG12   . ILE B 1 138 ? -36.895 29.709  -15.211 1.00 39.68  ? 138 ILE B HG12   1 
ATOM   9415  H HG13   . ILE B 1 138 ? -37.363 30.932  -14.317 1.00 39.68  ? 138 ILE B HG13   1 
ATOM   9416  H HG21   . ILE B 1 138 ? -35.976 32.799  -13.904 1.00 37.88  ? 138 ILE B HG21   1 
ATOM   9417  H HG22   . ILE B 1 138 ? -34.414 32.759  -14.187 1.00 37.88  ? 138 ILE B HG22   1 
ATOM   9418  H HG23   . ILE B 1 138 ? -35.426 33.118  -15.359 1.00 37.88  ? 138 ILE B HG23   1 
ATOM   9419  H HD11   . ILE B 1 138 ? -38.492 31.052  -16.279 1.00 44.05  ? 138 ILE B HD11   1 
ATOM   9420  H HD12   . ILE B 1 138 ? -37.449 32.250  -16.268 1.00 44.05  ? 138 ILE B HD12   1 
ATOM   9421  H HD13   . ILE B 1 138 ? -37.147 30.941  -17.115 1.00 44.05  ? 138 ILE B HD13   1 
ATOM   9422  N N      . ASP B 1 139 ? -32.565 32.102  -16.574 1.00 29.00  ? 139 ASP B N      1 
ATOM   9423  C CA     . ASP B 1 139 ? -31.202 32.543  -16.313 1.00 29.27  ? 139 ASP B CA     1 
ATOM   9424  C C      . ASP B 1 139 ? -31.183 33.452  -15.087 1.00 34.63  ? 139 ASP B C      1 
ATOM   9425  O O      . ASP B 1 139 ? -31.874 34.472  -15.056 1.00 30.52  ? 139 ASP B O      1 
ATOM   9426  C CB     . ASP B 1 139 ? -30.641 33.262  -17.536 1.00 30.87  ? 139 ASP B CB     1 
ATOM   9427  C CG     . ASP B 1 139 ? -29.166 33.609  -17.399 1.00 35.59  ? 139 ASP B CG     1 
ATOM   9428  O OD1    . ASP B 1 139 ? -28.515 33.178  -16.417 1.00 29.63  ? 139 ASP B OD1    1 
ATOM   9429  O OD2    . ASP B 1 139 ? -28.648 34.306  -18.300 1.00 34.91  ? 139 ASP B OD2    1 
ATOM   9430  H H      . ASP B 1 139 ? -32.964 32.540  -17.197 1.00 34.80  ? 139 ASP B H      1 
ATOM   9431  H HA     . ASP B 1 139 ? -30.642 31.772  -16.131 1.00 35.12  ? 139 ASP B HA     1 
ATOM   9432  H HB2    . ASP B 1 139 ? -30.743 32.689  -18.312 1.00 37.04  ? 139 ASP B HB2    1 
ATOM   9433  H HB3    . ASP B 1 139 ? -31.132 34.088  -17.668 1.00 37.04  ? 139 ASP B HB3    1 
ATOM   9434  N N      . ILE B 1 140 ? -30.417 33.072  -14.065 1.00 26.72  ? 140 ILE B N      1 
ATOM   9435  C CA     . ILE B 1 140 ? -30.314 33.882  -12.851 1.00 26.79  ? 140 ILE B CA     1 
ATOM   9436  C C      . ILE B 1 140 ? -28.871 34.288  -12.570 1.00 27.86  ? 140 ILE B C      1 
ATOM   9437  O O      . ILE B 1 140 ? -28.528 34.663  -11.453 1.00 27.47  ? 140 ILE B O      1 
ATOM   9438  C CB     . ILE B 1 140 ? -30.885 33.142  -11.624 1.00 27.54  ? 140 ILE B CB     1 
ATOM   9439  C CG1    . ILE B 1 140 ? -30.227 31.762  -11.471 1.00 27.17  ? 140 ILE B CG1    1 
ATOM   9440  C CG2    . ILE B 1 140 ? -32.397 33.010  -11.760 1.00 30.48  ? 140 ILE B CG2    1 
ATOM   9441  C CD1    . ILE B 1 140 ? -30.622 31.031  -10.203 1.00 32.56  ? 140 ILE B CD1    1 
ATOM   9442  H H      . ILE B 1 140 ? -29.948 32.351  -14.049 1.00 32.06  ? 140 ILE B H      1 
ATOM   9443  H HA     . ILE B 1 140 ? -30.824 34.699  -12.958 1.00 32.15  ? 140 ILE B HA     1 
ATOM   9444  H HB     . ILE B 1 140 ? -30.697 33.663  -10.828 1.00 33.05  ? 140 ILE B HB     1 
ATOM   9445  H HG12   . ILE B 1 140 ? -30.485 31.207  -12.224 1.00 32.61  ? 140 ILE B HG12   1 
ATOM   9446  H HG13   . ILE B 1 140 ? -29.263 31.871  -11.459 1.00 32.61  ? 140 ILE B HG13   1 
ATOM   9447  H HG21   . ILE B 1 140 ? -32.762 32.668  -10.929 1.00 36.58  ? 140 ILE B HG21   1 
ATOM   9448  H HG22   . ILE B 1 140 ? -32.773 33.884  -11.951 1.00 36.58  ? 140 ILE B HG22   1 
ATOM   9449  H HG23   . ILE B 1 140 ? -32.596 32.399  -12.487 1.00 36.58  ? 140 ILE B HG23   1 
ATOM   9450  H HD11   . ILE B 1 140 ? -30.143 30.188  -10.164 1.00 39.07  ? 140 ILE B HD11   1 
ATOM   9451  H HD12   . ILE B 1 140 ? -30.389 31.580  -9.438  1.00 39.07  ? 140 ILE B HD12   1 
ATOM   9452  H HD13   . ILE B 1 140 ? -31.578 30.868  -10.213 1.00 39.07  ? 140 ILE B HD13   1 
ATOM   9453  N N      . VAL B 1 141 ? -28.022 34.226  -13.588 1.00 28.31  ? 141 VAL B N      1 
ATOM   9454  C CA     . VAL B 1 141 ? -26.662 34.723  -13.437 1.00 27.38  ? 141 VAL B CA     1 
ATOM   9455  C C      . VAL B 1 141 ? -26.674 36.230  -13.193 1.00 29.43  ? 141 VAL B C      1 
ATOM   9456  O O      . VAL B 1 141 ? -27.605 36.933  -13.594 1.00 26.70  ? 141 VAL B O      1 
ATOM   9457  C CB     . VAL B 1 141 ? -25.784 34.408  -14.677 1.00 27.64  ? 141 VAL B CB     1 
ATOM   9458  C CG1    . VAL B 1 141 ? -26.096 35.355  -15.844 1.00 28.01  ? 141 VAL B CG1    1 
ATOM   9459  C CG2    . VAL B 1 141 ? -24.305 34.470  -14.302 1.00 26.18  ? 141 VAL B CG2    1 
ATOM   9460  H H      . VAL B 1 141 ? -28.203 33.907  -14.366 1.00 33.97  ? 141 VAL B H      1 
ATOM   9461  H HA     . VAL B 1 141 ? -26.255 34.298  -12.666 1.00 32.85  ? 141 VAL B HA     1 
ATOM   9462  H HB     . VAL B 1 141 ? -25.976 33.504  -14.972 1.00 33.17  ? 141 VAL B HB     1 
ATOM   9463  H HG11   . VAL B 1 141 ? -25.791 34.951  -16.671 1.00 33.61  ? 141 VAL B HG11   1 
ATOM   9464  H HG12   . VAL B 1 141 ? -27.054 35.502  -15.882 1.00 33.61  ? 141 VAL B HG12   1 
ATOM   9465  H HG13   . VAL B 1 141 ? -25.638 36.196  -15.702 1.00 33.61  ? 141 VAL B HG13   1 
ATOM   9466  H HG21   . VAL B 1 141 ? -23.777 34.163  -15.056 1.00 31.41  ? 141 VAL B HG21   1 
ATOM   9467  H HG22   . VAL B 1 141 ? -24.071 35.386  -14.086 1.00 31.41  ? 141 VAL B HG22   1 
ATOM   9468  H HG23   . VAL B 1 141 ? -24.149 33.897  -13.535 1.00 31.41  ? 141 VAL B HG23   1 
ATOM   9469  N N      . ARG B 1 142 ? -25.635 36.720  -12.533 1.00 28.27  ? 142 ARG B N      1 
ATOM   9470  C CA     . ARG B 1 142 ? -25.460 38.156  -12.338 1.00 32.60  ? 142 ARG B CA     1 
ATOM   9471  C C      . ARG B 1 142 ? -25.363 38.871  -13.683 1.00 32.78  ? 142 ARG B C      1 
ATOM   9472  O O      . ARG B 1 142 ? -24.891 38.303  -14.668 1.00 27.42  ? 142 ARG B O      1 
ATOM   9473  C CB     . ARG B 1 142 ? -24.210 38.431  -11.502 1.00 33.01  ? 142 ARG B CB     1 
ATOM   9474  C CG     . ARG B 1 142 ? -22.935 37.912  -12.141 1.00 35.51  ? 142 ARG B CG     1 
ATOM   9475  C CD     . ARG B 1 142 ? -21.761 37.987  -11.187 1.00 35.71  ? 142 ARG B CD     1 
ATOM   9476  N NE     . ARG B 1 142 ? -21.365 39.360  -10.896 1.00 43.07  ? 142 ARG B NE     1 
ATOM   9477  C CZ     . ARG B 1 142 ? -20.288 39.688  -10.191 1.00 48.98  ? 142 ARG B CZ     1 
ATOM   9478  N NH1    . ARG B 1 142 ? -19.492 38.741  -9.707  1.00 40.12  ? 142 ARG B NH1    1 
ATOM   9479  N NH2    . ARG B 1 142 ? -20.007 40.963  -9.970  1.00 50.31  ? 142 ARG B NH2    1 
ATOM   9480  H H      . ARG B 1 142 ? -25.013 36.240  -12.184 1.00 33.92  ? 142 ARG B H      1 
ATOM   9481  H HA     . ARG B 1 142 ? -26.226 38.513  -11.866 1.00 39.12  ? 142 ARG B HA     1 
ATOM   9482  H HB2    . ARG B 1 142 ? -24.117 39.388  -11.381 1.00 39.61  ? 142 ARG B HB2    1 
ATOM   9483  H HB3    . ARG B 1 142 ? -24.308 37.998  -10.640 1.00 39.61  ? 142 ARG B HB3    1 
ATOM   9484  H HG2    . ARG B 1 142 ? -23.057 36.985  -12.397 1.00 42.62  ? 142 ARG B HG2    1 
ATOM   9485  H HG3    . ARG B 1 142 ? -22.726 38.450  -12.920 1.00 42.62  ? 142 ARG B HG3    1 
ATOM   9486  H HD2    . ARG B 1 142 ? -22.012 37.568  -10.350 1.00 42.85  ? 142 ARG B HD2    1 
ATOM   9487  H HD3    . ARG B 1 142 ? -21.001 37.528  -11.578 1.00 42.85  ? 142 ARG B HD3    1 
ATOM   9488  H HE     . ARG B 1 142 ? -21.815 39.995  -11.262 1.00 51.68  ? 142 ARG B HE     1 
ATOM   9489  H HH11   . ARG B 1 142 ? -19.670 37.912  -9.846  1.00 48.14  ? 142 ARG B HH11   1 
ATOM   9490  H HH12   . ARG B 1 142 ? -18.796 38.959  -9.252  1.00 48.14  ? 142 ARG B HH12   1 
ATOM   9491  H HH21   . ARG B 1 142 ? -20.521 41.577  -10.284 1.00 60.37  ? 142 ARG B HH21   1 
ATOM   9492  H HH22   . ARG B 1 142 ? -19.309 41.177  -9.516  1.00 60.37  ? 142 ARG B HH22   1 
ATOM   9493  N N      . ASP B 1 143 ? -25.805 40.124  -13.720 1.00 32.83  ? 143 ASP B N      1 
ATOM   9494  C CA     . ASP B 1 143 ? -25.865 40.879  -14.969 1.00 34.33  ? 143 ASP B CA     1 
ATOM   9495  C C      . ASP B 1 143 ? -24.497 41.078  -15.605 1.00 33.27  ? 143 ASP B C      1 
ATOM   9496  O O      . ASP B 1 143 ? -24.390 41.145  -16.829 1.00 33.01  ? 143 ASP B O      1 
ATOM   9497  C CB     . ASP B 1 143 ? -26.517 42.241  -14.731 1.00 37.00  ? 143 ASP B CB     1 
ATOM   9498  C CG     . ASP B 1 143 ? -27.997 42.131  -14.397 1.00 44.38  ? 143 ASP B CG     1 
ATOM   9499  O OD1    . ASP B 1 143 ? -28.693 41.311  -15.033 1.00 41.71  ? 143 ASP B OD1    1 
ATOM   9500  O OD2    . ASP B 1 143 ? -28.464 42.863  -13.498 1.00 53.39  ? 143 ASP B OD2    1 
ATOM   9501  H H      . ASP B 1 143 ? -26.078 40.563  -13.032 1.00 39.40  ? 143 ASP B H      1 
ATOM   9502  H HA     . ASP B 1 143 ? -26.414 40.391  -15.602 1.00 41.20  ? 143 ASP B HA     1 
ATOM   9503  H HB2    . ASP B 1 143 ? -26.073 42.679  -13.988 1.00 44.40  ? 143 ASP B HB2    1 
ATOM   9504  H HB3    . ASP B 1 143 ? -26.429 42.778  -15.534 1.00 44.40  ? 143 ASP B HB3    1 
ATOM   9505  N N      . GLU B 1 144 ? -23.458 41.169  -14.776 1.00 34.23  ? 144 GLU B N      1 
ATOM   9506  C CA     . GLU B 1 144 ? -22.099 41.385  -15.272 1.00 33.98  ? 144 GLU B CA     1 
ATOM   9507  C C      . GLU B 1 144 ? -21.657 40.292  -16.241 1.00 32.84  ? 144 GLU B C      1 
ATOM   9508  O O      . GLU B 1 144 ? -20.847 40.548  -17.130 1.00 29.50  ? 144 GLU B O      1 
ATOM   9509  C CB     . GLU B 1 144 ? -21.090 41.457  -14.119 1.00 35.00  ? 144 GLU B CB     1 
ATOM   9510  C CG     . GLU B 1 144 ? -21.197 42.686  -13.237 1.00 40.21  ? 144 GLU B CG     1 
ATOM   9511  C CD     . GLU B 1 144 ? -22.256 42.561  -12.158 1.00 43.87  ? 144 GLU B CD     1 
ATOM   9512  O OE1    . GLU B 1 144 ? -22.943 41.523  -12.098 1.00 39.38  ? 144 GLU B OE1    1 
ATOM   9513  O OE2    . GLU B 1 144 ? -22.400 43.512  -11.362 1.00 59.33  ? 144 GLU B OE2    1 
ATOM   9514  H H      . GLU B 1 144 ? -23.513 41.108  -13.920 1.00 41.08  ? 144 GLU B H      1 
ATOM   9515  H HA     . GLU B 1 144 ? -22.070 42.231  -15.746 1.00 40.78  ? 144 GLU B HA     1 
ATOM   9516  H HB2    . GLU B 1 144 ? -21.201 40.673  -13.559 1.00 42.00  ? 144 GLU B HB2    1 
ATOM   9517  H HB3    . GLU B 1 144 ? -20.197 41.453  -14.498 1.00 42.00  ? 144 GLU B HB3    1 
ATOM   9518  H HG2    . GLU B 1 144 ? -20.343 42.835  -12.801 1.00 48.25  ? 144 GLU B HG2    1 
ATOM   9519  H HG3    . GLU B 1 144 ? -21.423 43.450  -13.790 1.00 48.25  ? 144 GLU B HG3    1 
ATOM   9520  N N      . ALA B 1 145 ? -22.176 39.078  -16.059 1.00 30.71  ? 145 ALA B N      1 
ATOM   9521  C CA     . ALA B 1 145 ? -21.788 37.938  -16.888 1.00 31.98  ? 145 ALA B CA     1 
ATOM   9522  C C      . ALA B 1 145 ? -22.072 38.187  -18.368 1.00 34.69  ? 145 ALA B C      1 
ATOM   9523  O O      . ALA B 1 145 ? -21.413 37.617  -19.238 1.00 32.09  ? 145 ALA B O      1 
ATOM   9524  C CB     . ALA B 1 145 ? -22.511 36.679  -16.425 1.00 28.21  ? 145 ALA B CB     1 
ATOM   9525  H H      . ALA B 1 145 ? -22.759 38.887  -15.457 1.00 36.86  ? 145 ALA B H      1 
ATOM   9526  H HA     . ALA B 1 145 ? -20.836 37.787  -16.794 1.00 38.38  ? 145 ALA B HA     1 
ATOM   9527  H HB1    . ALA B 1 145 ? -22.217 35.929  -16.965 1.00 33.86  ? 145 ALA B HB1    1 
ATOM   9528  H HB2    . ALA B 1 145 ? -22.300 36.519  -15.492 1.00 33.86  ? 145 ALA B HB2    1 
ATOM   9529  H HB3    . ALA B 1 145 ? -23.467 36.808  -16.529 1.00 33.86  ? 145 ALA B HB3    1 
ATOM   9530  N N      . HIS B 1 146 ? -23.053 39.039  -18.649 1.00 34.22  ? 146 HIS B N      1 
ATOM   9531  C CA     . HIS B 1 146 ? -23.464 39.298  -20.026 1.00 34.03  ? 146 HIS B CA     1 
ATOM   9532  C C      . HIS B 1 146 ? -22.693 40.448  -20.679 1.00 37.62  ? 146 HIS B C      1 
ATOM   9533  O O      . HIS B 1 146 ? -22.940 40.779  -21.839 1.00 37.11  ? 146 HIS B O      1 
ATOM   9534  C CB     . HIS B 1 146 ? -24.966 39.578  -20.071 1.00 35.94  ? 146 HIS B CB     1 
ATOM   9535  C CG     . HIS B 1 146 ? -25.806 38.362  -19.831 1.00 36.41  ? 146 HIS B CG     1 
ATOM   9536  N ND1    . HIS B 1 146 ? -26.519 38.164  -18.666 1.00 40.89  ? 146 HIS B ND1    1 
ATOM   9537  C CD2    . HIS B 1 146 ? -26.033 37.272  -20.601 1.00 36.37  ? 146 HIS B CD2    1 
ATOM   9538  C CE1    . HIS B 1 146 ? -27.156 37.008  -18.735 1.00 37.09  ? 146 HIS B CE1    1 
ATOM   9539  N NE2    . HIS B 1 146 ? -26.876 36.446  -19.896 1.00 43.12  ? 146 HIS B NE2    1 
ATOM   9540  H H      . HIS B 1 146 ? -23.498 39.481  -18.061 1.00 41.06  ? 146 HIS B H      1 
ATOM   9541  H HA     . HIS B 1 146 ? -23.304 38.502  -20.556 1.00 40.83  ? 146 HIS B HA     1 
ATOM   9542  H HB2    . HIS B 1 146 ? -25.184 40.230  -19.387 1.00 43.13  ? 146 HIS B HB2    1 
ATOM   9543  H HB3    . HIS B 1 146 ? -25.195 39.929  -20.946 1.00 43.13  ? 146 HIS B HB3    1 
ATOM   9544  H HD2    . HIS B 1 146 ? -25.685 37.113  -21.449 1.00 43.64  ? 146 HIS B HD2    1 
ATOM   9545  H HE1    . HIS B 1 146 ? -27.705 36.650  -18.076 1.00 44.51  ? 146 HIS B HE1    1 
ATOM   9546  H HE2    . HIS B 1 146 ? -27.176 35.688  -20.169 1.00 51.74  ? 146 HIS B HE2    1 
ATOM   9547  N N      . ASP B 1 147 ? -21.764 41.042  -19.935 1.00 31.49  ? 147 ASP B N      1 
ATOM   9548  C CA     . ASP B 1 147 ? -20.880 42.079  -20.455 1.00 36.46  ? 147 ASP B CA     1 
ATOM   9549  C C      . ASP B 1 147 ? -19.510 41.483  -20.740 1.00 32.02  ? 147 ASP B C      1 
ATOM   9550  O O      . ASP B 1 147 ? -18.663 41.410  -19.853 1.00 28.70  ? 147 ASP B O      1 
ATOM   9551  C CB     . ASP B 1 147 ? -20.752 43.239  -19.460 1.00 36.43  ? 147 ASP B CB     1 
ATOM   9552  C CG     . ASP B 1 147 ? -19.960 44.420  -20.025 1.00 42.64  ? 147 ASP B CG     1 
ATOM   9553  O OD1    . ASP B 1 147 ? -19.285 44.268  -21.067 1.00 39.56  ? 147 ASP B OD1    1 
ATOM   9554  O OD2    . ASP B 1 147 ? -20.009 45.510  -19.419 1.00 46.95  ? 147 ASP B OD2    1 
ATOM   9555  H H      . ASP B 1 147 ? -21.623 40.859  -19.107 1.00 37.79  ? 147 ASP B H      1 
ATOM   9556  H HA     . ASP B 1 147 ? -21.237 42.432  -21.284 1.00 43.75  ? 147 ASP B HA     1 
ATOM   9557  H HB2    . ASP B 1 147 ? -21.640 43.557  -19.232 1.00 43.71  ? 147 ASP B HB2    1 
ATOM   9558  H HB3    . ASP B 1 147 ? -20.299 42.926  -18.662 1.00 43.71  ? 147 ASP B HB3    1 
ATOM   9559  N N      . ALA B 1 148 ? -19.295 41.089  -21.991 1.00 33.34  ? 148 ALA B N      1 
ATOM   9560  C CA     . ALA B 1 148 ? -18.084 40.380  -22.398 1.00 35.27  ? 148 ALA B CA     1 
ATOM   9561  C C      . ALA B 1 148 ? -16.791 41.168  -22.169 1.00 33.18  ? 148 ALA B C      1 
ATOM   9562  O O      . ALA B 1 148 ? -15.712 40.583  -22.121 1.00 34.91  ? 148 ALA B O      1 
ATOM   9563  C CB     . ALA B 1 148 ? -18.197 39.994  -23.866 1.00 34.81  ? 148 ALA B CB     1 
ATOM   9564  H H      . ALA B 1 148 ? -19.847 41.223  -22.637 1.00 40.01  ? 148 ALA B H      1 
ATOM   9565  H HA     . ALA B 1 148 ? -18.020 39.560  -21.884 1.00 42.32  ? 148 ALA B HA     1 
ATOM   9566  H HB1    . ALA B 1 148 ? -17.391 39.524  -24.131 1.00 41.77  ? 148 ALA B HB1    1 
ATOM   9567  H HB2    . ALA B 1 148 ? -18.969 39.419  -23.982 1.00 41.77  ? 148 ALA B HB2    1 
ATOM   9568  H HB3    . ALA B 1 148 ? -18.301 40.799  -24.397 1.00 41.77  ? 148 ALA B HB3    1 
ATOM   9569  N N      . GLY B 1 149 ? -16.889 42.488  -22.034 1.00 27.20  ? 149 GLY B N      1 
ATOM   9570  C CA     . GLY B 1 149 ? -15.704 43.320  -21.891 1.00 32.93  ? 149 GLY B CA     1 
ATOM   9571  C C      . GLY B 1 149 ? -15.361 43.653  -20.447 1.00 37.96  ? 149 GLY B C      1 
ATOM   9572  O O      . GLY B 1 149 ? -14.294 44.205  -20.154 1.00 40.45  ? 149 GLY B O      1 
ATOM   9573  H H      . GLY B 1 149 ? -17.630 42.924  -22.023 1.00 32.64  ? 149 GLY B H      1 
ATOM   9574  H HA2    . GLY B 1 149 ? -14.940 42.878  -22.292 1.00 39.51  ? 149 GLY B HA2    1 
ATOM   9575  H HA3    . GLY B 1 149 ? -15.848 44.155  -22.363 1.00 39.51  ? 149 GLY B HA3    1 
ATOM   9576  N N      . LEU B 1 150 ? -16.266 43.312  -19.540 1.00 32.73  ? 150 LEU B N      1 
ATOM   9577  C CA     . LEU B 1 150 ? -16.122 43.695  -18.138 1.00 35.35  ? 150 LEU B CA     1 
ATOM   9578  C C      . LEU B 1 150 ? -15.225 42.736  -17.346 1.00 34.44  ? 150 LEU B C      1 
ATOM   9579  O O      . LEU B 1 150 ? -15.567 41.566  -17.155 1.00 31.82  ? 150 LEU B O      1 
ATOM   9580  C CB     . LEU B 1 150 ? -17.503 43.771  -17.492 1.00 31.83  ? 150 LEU B CB     1 
ATOM   9581  C CG     . LEU B 1 150 ? -17.544 44.270  -16.052 1.00 34.03  ? 150 LEU B CG     1 
ATOM   9582  C CD1    . LEU B 1 150 ? -17.097 45.720  -15.987 1.00 36.08  ? 150 LEU B CD1    1 
ATOM   9583  C CD2    . LEU B 1 150 ? -18.942 44.104  -15.482 1.00 36.41  ? 150 LEU B CD2    1 
ATOM   9584  H H      . LEU B 1 150 ? -16.976 42.857  -19.706 1.00 39.28  ? 150 LEU B H      1 
ATOM   9585  H HA     . LEU B 1 150 ? -15.724 44.578  -18.094 1.00 42.41  ? 150 LEU B HA     1 
ATOM   9586  H HB2    . LEU B 1 150 ? -18.053 44.370  -18.020 1.00 38.19  ? 150 LEU B HB2    1 
ATOM   9587  H HB3    . LEU B 1 150 ? -17.893 42.883  -17.502 1.00 38.19  ? 150 LEU B HB3    1 
ATOM   9588  H HG     . LEU B 1 150 ? -16.936 43.742  -15.513 1.00 40.84  ? 150 LEU B HG     1 
ATOM   9589  H HD11   . LEU B 1 150 ? -17.241 46.053  -15.088 1.00 43.30  ? 150 LEU B HD11   1 
ATOM   9590  H HD12   . LEU B 1 150 ? -16.155 45.772  -16.211 1.00 43.30  ? 150 LEU B HD12   1 
ATOM   9591  H HD13   . LEU B 1 150 ? -17.618 46.239  -16.619 1.00 43.30  ? 150 LEU B HD13   1 
ATOM   9592  H HD21   . LEU B 1 150 ? -18.934 44.361  -14.547 1.00 43.69  ? 150 LEU B HD21   1 
ATOM   9593  H HD22   . LEU B 1 150 ? -19.554 44.672  -15.976 1.00 43.69  ? 150 LEU B HD22   1 
ATOM   9594  H HD23   . LEU B 1 150 ? -19.209 43.176  -15.569 1.00 43.69  ? 150 LEU B HD23   1 
ATOM   9595  N N      . ASP B 1 151 ? -14.088 43.249  -16.879 1.00 30.59  ? 151 ASP B N      1 
ATOM   9596  C CA     . ASP B 1 151 ? -13.134 42.470  -16.091 1.00 31.56  ? 151 ASP B CA     1 
ATOM   9597  C C      . ASP B 1 151 ? -13.470 42.528  -14.595 1.00 33.28  ? 151 ASP B C      1 
ATOM   9598  O O      . ASP B 1 151 ? -12.999 43.417  -13.886 1.00 33.48  ? 151 ASP B O      1 
ATOM   9599  C CB     . ASP B 1 151 ? -11.712 42.989  -16.335 1.00 31.91  ? 151 ASP B CB     1 
ATOM   9600  C CG     . ASP B 1 151 ? -10.638 42.113  -15.696 1.00 44.70  ? 151 ASP B CG     1 
ATOM   9601  O OD1    . ASP B 1 151 ? -10.971 41.223  -14.886 1.00 46.53  ? 151 ASP B OD1    1 
ATOM   9602  O OD2    . ASP B 1 151 ? -9.446  42.325  -16.002 1.00 49.82  ? 151 ASP B OD2    1 
ATOM   9603  H H      . ASP B 1 151 ? -13.842 44.063  -17.008 1.00 36.71  ? 151 ASP B H      1 
ATOM   9604  H HA     . ASP B 1 151 ? -13.167 41.542  -16.372 1.00 37.87  ? 151 ASP B HA     1 
ATOM   9605  H HB2    . ASP B 1 151 ? -11.547 43.012  -17.291 1.00 38.29  ? 151 ASP B HB2    1 
ATOM   9606  H HB3    . ASP B 1 151 ? -11.631 43.882  -15.965 1.00 38.29  ? 151 ASP B HB3    1 
ATOM   9607  N N      . VAL B 1 152 ? -14.286 41.584  -14.131 1.00 28.85  ? 152 VAL B N      1 
ATOM   9608  C CA     . VAL B 1 152 ? -14.608 41.446  -12.705 1.00 27.85  ? 152 VAL B CA     1 
ATOM   9609  C C      . VAL B 1 152 ? -14.483 40.000  -12.232 1.00 30.77  ? 152 VAL B C      1 
ATOM   9610  O O      . VAL B 1 152 ? -14.697 39.065  -13.002 1.00 25.62  ? 152 VAL B O      1 
ATOM   9611  C CB     . VAL B 1 152 ? -16.040 41.923  -12.383 1.00 29.19  ? 152 VAL B CB     1 
ATOM   9612  C CG1    . VAL B 1 152 ? -16.166 43.420  -12.612 1.00 33.22  ? 152 VAL B CG1    1 
ATOM   9613  C CG2    . VAL B 1 152 ? -17.064 41.161  -13.202 1.00 29.89  ? 152 VAL B CG2    1 
ATOM   9614  H H      . VAL B 1 152 ? -14.674 41.000  -14.629 1.00 34.62  ? 152 VAL B H      1 
ATOM   9615  H HA     . VAL B 1 152 ? -13.991 41.981  -12.181 1.00 33.42  ? 152 VAL B HA     1 
ATOM   9616  H HB     . VAL B 1 152 ? -16.223 41.751  -11.446 1.00 35.03  ? 152 VAL B HB     1 
ATOM   9617  H HG11   . VAL B 1 152 ? -17.093 43.680  -12.494 1.00 39.86  ? 152 VAL B HG11   1 
ATOM   9618  H HG12   . VAL B 1 152 ? -15.607 43.885  -11.970 1.00 39.86  ? 152 VAL B HG12   1 
ATOM   9619  H HG13   . VAL B 1 152 ? -15.876 43.627  -13.514 1.00 39.86  ? 152 VAL B HG13   1 
ATOM   9620  H HG21   . VAL B 1 152 ? -17.939 41.554  -13.054 1.00 35.87  ? 152 VAL B HG21   1 
ATOM   9621  H HG22   . VAL B 1 152 ? -16.830 41.223  -14.141 1.00 35.87  ? 152 VAL B HG22   1 
ATOM   9622  H HG23   . VAL B 1 152 ? -17.069 40.232  -12.923 1.00 35.87  ? 152 VAL B HG23   1 
ATOM   9623  N N      . LYS B 1 153 ? -14.160 39.833  -10.954 1.00 25.43  ? 153 LYS B N      1 
ATOM   9624  C CA     . LYS B 1 153 ? -14.038 38.510  -10.347 1.00 21.93  ? 153 LYS B CA     1 
ATOM   9625  C C      . LYS B 1 153 ? -15.356 37.755  -10.261 1.00 25.70  ? 153 LYS B C      1 
ATOM   9626  O O      . LYS B 1 153 ? -16.421 38.356  -10.139 1.00 22.76  ? 153 LYS B O      1 
ATOM   9627  C CB     . LYS B 1 153 ? -13.466 38.620  -8.936  1.00 27.30  ? 153 LYS B CB     1 
ATOM   9628  C CG     . LYS B 1 153 ? -12.010 39.006  -8.850  1.00 34.17  ? 153 LYS B CG     1 
ATOM   9629  C CD     . LYS B 1 153 ? -11.551 38.906  -7.395  1.00 34.90  ? 153 LYS B CD     1 
ATOM   9630  C CE     . LYS B 1 153 ? -10.074 39.210  -7.220  1.00 37.67  ? 153 LYS B CE     1 
ATOM   9631  N NZ     . LYS B 1 153 ? -9.673  39.016  -5.789  1.00 36.56  ? 153 LYS B NZ     1 
ATOM   9632  H H      . LYS B 1 153 ? -14.004 40.479  -10.409 1.00 30.51  ? 153 LYS B H      1 
ATOM   9633  H HA     . LYS B 1 153 ? -13.424 37.978  -10.877 1.00 26.32  ? 153 LYS B HA     1 
ATOM   9634  H HB2    . LYS B 1 153 ? -13.973 39.290  -8.451  1.00 32.76  ? 153 LYS B HB2    1 
ATOM   9635  H HB3    . LYS B 1 153 ? -13.564 37.760  -8.498  1.00 32.76  ? 153 LYS B HB3    1 
ATOM   9636  H HG2    . LYS B 1 153 ? -11.478 38.403  -9.390  1.00 41.01  ? 153 LYS B HG2    1 
ATOM   9637  H HG3    . LYS B 1 153 ? -11.897 39.922  -9.149  1.00 41.01  ? 153 LYS B HG3    1 
ATOM   9638  H HD2    . LYS B 1 153 ? -12.053 39.542  -6.861  1.00 41.89  ? 153 LYS B HD2    1 
ATOM   9639  H HD3    . LYS B 1 153 ? -11.711 38.005  -7.075  1.00 41.89  ? 153 LYS B HD3    1 
ATOM   9640  H HE2    . LYS B 1 153 ? -9.551  38.607  -7.771  1.00 45.21  ? 153 LYS B HE2    1 
ATOM   9641  H HE3    . LYS B 1 153 ? -9.901  40.132  -7.466  1.00 45.21  ? 153 LYS B HE3    1 
ATOM   9642  H HZ1    . LYS B 1 153 ? -8.807  39.195  -5.689  1.00 43.88  ? 153 LYS B HZ1    1 
ATOM   9643  H HZ2    . LYS B 1 153 ? -10.143 39.561  -5.265  1.00 43.88  ? 153 LYS B HZ2    1 
ATOM   9644  H HZ3    . LYS B 1 153 ? -9.825  38.175  -5.542  1.00 43.88  ? 153 LYS B HZ3    1 
ATOM   9645  N N      . PHE B 1 154 ? -15.254 36.425  -10.311 1.00 22.37  ? 154 PHE B N      1 
ATOM   9646  C CA     . PHE B 1 154 ? -16.371 35.507  -10.097 1.00 19.58  ? 154 PHE B CA     1 
ATOM   9647  C C      . PHE B 1 154 ? -17.618 35.943  -10.853 1.00 25.02  ? 154 PHE B C      1 
ATOM   9648  O O      . PHE B 1 154 ? -18.729 35.979  -10.331 1.00 23.37  ? 154 PHE B O      1 
ATOM   9649  C CB     . PHE B 1 154 ? -16.611 35.346  -8.594  1.00 22.84  ? 154 PHE B CB     1 
ATOM   9650  C CG     . PHE B 1 154 ? -15.412 34.780  -7.883  1.00 23.05  ? 154 PHE B CG     1 
ATOM   9651  C CD1    . PHE B 1 154 ? -15.036 33.459  -8.092  1.00 23.49  ? 154 PHE B CD1    1 
ATOM   9652  C CD2    . PHE B 1 154 ? -14.626 35.573  -7.070  1.00 24.30  ? 154 PHE B CD2    1 
ATOM   9653  C CE1    . PHE B 1 154 ? -13.911 32.940  -7.474  1.00 21.53  ? 154 PHE B CE1    1 
ATOM   9654  C CE2    . PHE B 1 154 ? -13.510 35.063  -6.447  1.00 24.83  ? 154 PHE B CE2    1 
ATOM   9655  C CZ     . PHE B 1 154 ? -13.146 33.741  -6.655  1.00 24.14  ? 154 PHE B CZ     1 
ATOM   9656  H H      . PHE B 1 154 ? -14.515 36.017  -10.474 1.00 26.85  ? 154 PHE B H      1 
ATOM   9657  H HA     . PHE B 1 154 ? -16.116 34.637  -10.442 1.00 23.50  ? 154 PHE B HA     1 
ATOM   9658  H HB2    . PHE B 1 154 ? -16.808 36.214  -8.209  1.00 27.41  ? 154 PHE B HB2    1 
ATOM   9659  H HB3    . PHE B 1 154 ? -17.357 34.742  -8.454  1.00 27.41  ? 154 PHE B HB3    1 
ATOM   9660  H HD1    . PHE B 1 154 ? -15.547 32.917  -8.649  1.00 28.19  ? 154 PHE B HD1    1 
ATOM   9661  H HD2    . PHE B 1 154 ? -14.862 36.462  -6.931  1.00 29.17  ? 154 PHE B HD2    1 
ATOM   9662  H HE1    . PHE B 1 154 ? -13.673 32.051  -7.610  1.00 25.83  ? 154 PHE B HE1    1 
ATOM   9663  H HE2    . PHE B 1 154 ? -12.996 35.606  -5.894  1.00 29.80  ? 154 PHE B HE2    1 
ATOM   9664  H HZ     . PHE B 1 154 ? -12.396 33.392  -6.230  1.00 28.97  ? 154 PHE B HZ     1 
ATOM   9665  N N      . LYS B 1 155 ? -17.384 36.226  -12.131 1.00 24.43  ? 155 LYS B N      1 
ATOM   9666  C CA     . LYS B 1 155 ? -18.405 36.658  -13.070 1.00 26.63  ? 155 LYS B CA     1 
ATOM   9667  C C      . LYS B 1 155 ? -19.533 35.639  -13.221 1.00 24.00  ? 155 LYS B C      1 
ATOM   9668  O O      . LYS B 1 155 ? -20.621 35.973  -13.678 1.00 28.06  ? 155 LYS B O      1 
ATOM   9669  C CB     . LYS B 1 155 ? -17.744 36.916  -14.426 1.00 27.69  ? 155 LYS B CB     1 
ATOM   9670  C CG     . LYS B 1 155 ? -18.246 38.102  -15.165 1.00 31.71  ? 155 LYS B CG     1 
ATOM   9671  C CD     . LYS B 1 155 ? -17.318 38.427  -16.316 1.00 31.02  ? 155 LYS B CD     1 
ATOM   9672  C CE     . LYS B 1 155 ? -17.936 39.454  -17.227 1.00 34.54  ? 155 LYS B CE     1 
ATOM   9673  N NZ     . LYS B 1 155 ? -17.178 39.584  -18.490 1.00 27.92  ? 155 LYS B NZ     1 
ATOM   9674  H H      . LYS B 1 155 ? -16.603 36.169  -12.486 1.00 29.31  ? 155 LYS B H      1 
ATOM   9675  H HA     . LYS B 1 155 ? -18.791 37.491  -12.758 1.00 31.96  ? 155 LYS B HA     1 
ATOM   9676  H HB2    . LYS B 1 155 ? -16.794 37.047  -14.291 1.00 33.23  ? 155 LYS B HB2    1 
ATOM   9677  H HB3    . LYS B 1 155 ? -17.887 36.140  -14.990 1.00 33.23  ? 155 LYS B HB3    1 
ATOM   9678  H HG2    . LYS B 1 155 ? -19.126 37.912  -15.519 1.00 38.05  ? 155 LYS B HG2    1 
ATOM   9679  H HG3    . LYS B 1 155 ? -18.277 38.867  -14.569 1.00 38.05  ? 155 LYS B HG3    1 
ATOM   9680  H HD2    . LYS B 1 155 ? -16.487 38.787  -15.968 1.00 37.22  ? 155 LYS B HD2    1 
ATOM   9681  H HD3    . LYS B 1 155 ? -17.149 37.623  -16.831 1.00 37.22  ? 155 LYS B HD3    1 
ATOM   9682  H HE2    . LYS B 1 155 ? -18.838 39.176  -17.448 1.00 41.44  ? 155 LYS B HE2    1 
ATOM   9683  H HE3    . LYS B 1 155 ? -17.946 40.317  -16.784 1.00 41.44  ? 155 LYS B HE3    1 
ATOM   9684  H HZ1    . LYS B 1 155 ? -17.558 40.197  -19.011 1.00 33.50  ? 155 LYS B HZ1    1 
ATOM   9685  H HZ2    . LYS B 1 155 ? -16.340 39.830  -18.318 1.00 33.50  ? 155 LYS B HZ2    1 
ATOM   9686  H HZ3    . LYS B 1 155 ? -17.168 38.805  -18.920 1.00 33.50  ? 155 LYS B HZ3    1 
ATOM   9687  N N      . GLY B 1 156 ? -19.270 34.392  -12.842 1.00 22.17  ? 156 GLY B N      1 
ATOM   9688  C CA     . GLY B 1 156 ? -20.254 33.334  -12.988 1.00 24.25  ? 156 GLY B CA     1 
ATOM   9689  C C      . GLY B 1 156 ? -21.270 33.217  -11.866 1.00 20.19  ? 156 GLY B C      1 
ATOM   9690  O O      . GLY B 1 156 ? -22.172 32.385  -11.937 1.00 23.97  ? 156 GLY B O      1 
ATOM   9691  H H      . GLY B 1 156 ? -18.526 34.133  -12.498 1.00 26.60  ? 156 GLY B H      1 
ATOM   9692  H HA2    . GLY B 1 156 ? -20.740 33.467  -13.817 1.00 29.10  ? 156 GLY B HA2    1 
ATOM   9693  H HA3    . GLY B 1 156 ? -19.788 32.485  -13.052 1.00 29.10  ? 156 GLY B HA3    1 
ATOM   9694  N N      . ASN B 1 157 ? -21.124 34.031  -10.827 1.00 24.69  ? 157 ASN B N      1 
ATOM   9695  C CA     . ASN B 1 157 ? -22.020 33.977  -9.673  1.00 25.64  ? 157 ASN B CA     1 
ATOM   9696  C C      . ASN B 1 157 ? -23.484 34.140  -10.033 1.00 26.13  ? 157 ASN B C      1 
ATOM   9697  O O      . ASN B 1 157 ? -23.837 34.912  -10.926 1.00 27.88  ? 157 ASN B O      1 
ATOM   9698  C CB     . ASN B 1 157 ? -21.657 35.067  -8.662  1.00 26.63  ? 157 ASN B CB     1 
ATOM   9699  C CG     . ASN B 1 157 ? -20.455 34.713  -7.820  1.00 27.52  ? 157 ASN B CG     1 
ATOM   9700  O OD1    . ASN B 1 157 ? -19.884 33.628  -7.946  1.00 25.87  ? 157 ASN B OD1    1 
ATOM   9701  N ND2    . ASN B 1 157 ? -20.051 35.642  -6.960  1.00 25.29  ? 157 ASN B ND2    1 
ATOM   9702  H H      . ASN B 1 157 ? -20.510 34.629  -10.763 1.00 29.63  ? 157 ASN B H      1 
ATOM   9703  H HA     . ASN B 1 157 ? -21.921 33.115  -9.239  1.00 30.77  ? 157 ASN B HA     1 
ATOM   9704  H HB2    . ASN B 1 157 ? -21.451 35.884  -9.140  1.00 31.95  ? 157 ASN B HB2    1 
ATOM   9705  H HB3    . ASN B 1 157 ? -22.409 35.210  -8.067  1.00 31.95  ? 157 ASN B HB3    1 
ATOM   9706  H HD21   . ASN B 1 157 ? -19.371 35.494  -6.455  1.00 30.35  ? 157 ASN B HD21   1 
ATOM   9707  H HD22   . ASN B 1 157 ? -20.470 36.391  -6.909  1.00 30.35  ? 157 ASN B HD22   1 
ATOM   9708  N N      . ILE B 1 158 ? -24.328 33.417  -9.310  1.00 22.95  ? 158 ILE B N      1 
ATOM   9709  C CA     . ILE B 1 158 ? -25.765 33.622  -9.353  1.00 25.78  ? 158 ILE B CA     1 
ATOM   9710  C C      . ILE B 1 158 ? -26.131 34.924  -8.638  1.00 29.24  ? 158 ILE B C      1 
ATOM   9711  O O      . ILE B 1 158 ? -25.578 35.239  -7.582  1.00 24.73  ? 158 ILE B O      1 
ATOM   9712  C CB     . ILE B 1 158 ? -26.508 32.432  -8.705  1.00 29.43  ? 158 ILE B CB     1 
ATOM   9713  C CG1    . ILE B 1 158 ? -26.412 31.214  -9.631  1.00 28.55  ? 158 ILE B CG1    1 
ATOM   9714  C CG2    . ILE B 1 158 ? -27.985 32.774  -8.405  1.00 27.77  ? 158 ILE B CG2    1 
ATOM   9715  C CD1    . ILE B 1 158 ? -26.915 29.916  -9.029  1.00 26.84  ? 158 ILE B CD1    1 
ATOM   9716  H H      . ILE B 1 158 ? -24.086 32.788  -8.776  1.00 27.54  ? 158 ILE B H      1 
ATOM   9717  H HA     . ILE B 1 158 ? -26.051 33.692  -10.277 1.00 30.94  ? 158 ILE B HA     1 
ATOM   9718  H HB     . ILE B 1 158 ? -26.068 32.216  -7.868  1.00 35.31  ? 158 ILE B HB     1 
ATOM   9719  H HG12   . ILE B 1 158 ? -26.936 31.390  -10.428 1.00 34.26  ? 158 ILE B HG12   1 
ATOM   9720  H HG13   . ILE B 1 158 ? -25.482 31.083  -9.874  1.00 34.26  ? 158 ILE B HG13   1 
ATOM   9721  H HG21   . ILE B 1 158 ? -28.469 31.957  -8.211  1.00 33.33  ? 158 ILE B HG21   1 
ATOM   9722  H HG22   . ILE B 1 158 ? -28.026 33.365  -7.637  1.00 33.33  ? 158 ILE B HG22   1 
ATOM   9723  H HG23   . ILE B 1 158 ? -28.371 33.209  -9.181  1.00 33.33  ? 158 ILE B HG23   1 
ATOM   9724  H HD11   . ILE B 1 158 ? -26.641 29.179  -9.597  1.00 32.21  ? 158 ILE B HD11   1 
ATOM   9725  H HD12   . ILE B 1 158 ? -26.534 29.811  -8.143  1.00 32.21  ? 158 ILE B HD12   1 
ATOM   9726  H HD13   . ILE B 1 158 ? -27.883 29.946  -8.971  1.00 32.21  ? 158 ILE B HD13   1 
ATOM   9727  N N      . ASP B 1 159 ? -27.049 35.682  -9.230  1.00 26.19  ? 159 ASP B N      1 
ATOM   9728  C CA     . ASP B 1 159 ? -27.625 36.851  -8.562  1.00 30.16  ? 159 ASP B CA     1 
ATOM   9729  C C      . ASP B 1 159 ? -28.691 36.362  -7.595  1.00 27.00  ? 159 ASP B C      1 
ATOM   9730  O O      . ASP B 1 159 ? -29.750 35.885  -8.008  1.00 31.55  ? 159 ASP B O      1 
ATOM   9731  C CB     . ASP B 1 159 ? -28.220 37.830  -9.582  1.00 30.79  ? 159 ASP B CB     1 
ATOM   9732  C CG     . ASP B 1 159 ? -28.704 39.134  -8.946  1.00 37.67  ? 159 ASP B CG     1 
ATOM   9733  O OD1    . ASP B 1 159 ? -29.073 39.139  -7.751  1.00 34.76  ? 159 ASP B OD1    1 
ATOM   9734  O OD2    . ASP B 1 159 ? -28.718 40.160  -9.654  1.00 35.82  ? 159 ASP B OD2    1 
ATOM   9735  H H      . ASP B 1 159 ? -27.358 35.542  -10.020 1.00 31.43  ? 159 ASP B H      1 
ATOM   9736  H HA     . ASP B 1 159 ? -26.937 37.313  -8.058  1.00 36.19  ? 159 ASP B HA     1 
ATOM   9737  H HB2    . ASP B 1 159 ? -27.542 38.051  -10.236 1.00 36.95  ? 159 ASP B HB2    1 
ATOM   9738  H HB3    . ASP B 1 159 ? -28.978 37.410  -10.019 1.00 36.95  ? 159 ASP B HB3    1 
ATOM   9739  N N      . ILE B 1 160 ? -28.408 36.476  -6.305  1.00 29.73  ? 160 ILE B N      1 
ATOM   9740  C CA     . ILE B 1 160 ? -29.323 35.968  -5.287  1.00 34.25  ? 160 ILE B CA     1 
ATOM   9741  C C      . ILE B 1 160 ? -30.664 36.704  -5.344  1.00 36.79  ? 160 ILE B C      1 
ATOM   9742  O O      . ILE B 1 160 ? -31.701 36.133  -5.024  1.00 35.71  ? 160 ILE B O      1 
ATOM   9743  C CB     . ILE B 1 160 ? -28.718 36.097  -3.871  1.00 34.48  ? 160 ILE B CB     1 
ATOM   9744  C CG1    . ILE B 1 160 ? -27.417 35.293  -3.760  1.00 39.61  ? 160 ILE B CG1    1 
ATOM   9745  C CG2    . ILE B 1 160 ? -29.709 35.629  -2.802  1.00 39.84  ? 160 ILE B CG2    1 
ATOM   9746  C CD1    . ILE B 1 160 ? -27.580 33.783  -3.954  1.00 37.22  ? 160 ILE B CD1    1 
ATOM   9747  H H      . ILE B 1 160 ? -27.696 36.842  -5.991  1.00 35.68  ? 160 ILE B H      1 
ATOM   9748  H HA     . ILE B 1 160 ? -29.495 35.029  -5.458  1.00 41.10  ? 160 ILE B HA     1 
ATOM   9749  H HB     . ILE B 1 160 ? -28.514 37.032  -3.710  1.00 41.38  ? 160 ILE B HB     1 
ATOM   9750  H HG12   . ILE B 1 160 ? -26.795 35.610  -4.433  1.00 47.53  ? 160 ILE B HG12   1 
ATOM   9751  H HG13   . ILE B 1 160 ? -27.042 35.435  -2.877  1.00 47.53  ? 160 ILE B HG13   1 
ATOM   9752  H HG21   . ILE B 1 160 ? -29.229 35.484  -1.972  1.00 47.81  ? 160 ILE B HG21   1 
ATOM   9753  H HG22   . ILE B 1 160 ? -30.387 36.311  -2.676  1.00 47.81  ? 160 ILE B HG22   1 
ATOM   9754  H HG23   . ILE B 1 160 ? -30.121 34.801  -3.094  1.00 47.81  ? 160 ILE B HG23   1 
ATOM   9755  H HD11   . ILE B 1 160 ? -26.720 33.355  -3.816  1.00 44.66  ? 160 ILE B HD11   1 
ATOM   9756  H HD12   . ILE B 1 160 ? -28.222 33.445  -3.310  1.00 44.66  ? 160 ILE B HD12   1 
ATOM   9757  H HD13   . ILE B 1 160 ? -27.892 33.610  -4.856  1.00 44.66  ? 160 ILE B HD13   1 
ATOM   9758  N N      . LYS B 1 161 ? -30.649 37.965  -5.763  1.00 35.64  ? 161 LYS B N      1 
ATOM   9759  C CA     . LYS B 1 161 ? -31.886 38.734  -5.823  1.00 37.55  ? 161 LYS B CA     1 
ATOM   9760  C C      . LYS B 1 161 ? -32.798 38.188  -6.914  1.00 37.22  ? 161 LYS B C      1 
ATOM   9761  O O      . LYS B 1 161 ? -34.017 38.119  -6.729  1.00 37.37  ? 161 LYS B O      1 
ATOM   9762  C CB     . LYS B 1 161 ? -31.594 40.222  -6.049  1.00 41.72  ? 161 LYS B CB     1 
ATOM   9763  C CG     . LYS B 1 161 ? -30.820 40.894  -4.907  1.00 49.19  ? 161 LYS B CG     1 
ATOM   9764  C CD     . LYS B 1 161 ? -31.388 40.544  -3.524  1.00 65.21  ? 161 LYS B CD     1 
ATOM   9765  C CE     . LYS B 1 161 ? -30.581 41.168  -2.394  1.00 72.80  ? 161 LYS B CE     1 
ATOM   9766  N NZ     . LYS B 1 161 ? -30.776 42.639  -2.281  1.00 59.16  ? 161 LYS B NZ     1 
ATOM   9767  H H      . LYS B 1 161 ? -29.947 38.393  -6.014  1.00 42.77  ? 161 LYS B H      1 
ATOM   9768  H HA     . LYS B 1 161 ? -32.364 38.634  -4.987  1.00 45.06  ? 161 LYS B HA     1 
ATOM   9769  H HB2    . LYS B 1 161 ? -31.073 40.321  -6.860  1.00 50.07  ? 161 LYS B HB2    1 
ATOM   9770  H HB3    . LYS B 1 161 ? -32.438 40.691  -6.146  1.00 50.07  ? 161 LYS B HB3    1 
ATOM   9771  H HG2    . LYS B 1 161 ? -29.896 40.601  -4.935  1.00 59.03  ? 161 LYS B HG2    1 
ATOM   9772  H HG3    . LYS B 1 161 ? -30.867 41.857  -5.016  1.00 59.03  ? 161 LYS B HG3    1 
ATOM   9773  H HD2    . LYS B 1 161 ? -32.301 40.866  -3.461  1.00 78.25  ? 161 LYS B HD2    1 
ATOM   9774  H HD3    . LYS B 1 161 ? -31.360 39.585  -3.392  1.00 78.25  ? 161 LYS B HD3    1 
ATOM   9775  H HE2    . LYS B 1 161 ? -30.852 40.765  -1.554  1.00 87.36  ? 161 LYS B HE2    1 
ATOM   9776  H HE3    . LYS B 1 161 ? -29.638 41.003  -2.552  1.00 87.36  ? 161 LYS B HE3    1 
ATOM   9777  H HZ1    . LYS B 1 161 ? -30.287 42.960  -1.610  1.00 70.99  ? 161 LYS B HZ1    1 
ATOM   9778  H HZ2    . LYS B 1 161 ? -30.527 43.038  -3.037  1.00 70.99  ? 161 LYS B HZ2    1 
ATOM   9779  H HZ3    . LYS B 1 161 ? -31.633 42.821  -2.127  1.00 70.99  ? 161 LYS B HZ3    1 
ATOM   9780  N N      . LYS B 1 162 ? -32.212 37.768  -8.034  1.00 33.47  ? 162 LYS B N      1 
ATOM   9781  C CA     . LYS B 1 162 ? -32.991 37.171  -9.114  1.00 31.15  ? 162 LYS B CA     1 
ATOM   9782  C C      . LYS B 1 162 ? -33.576 35.839  -8.683  1.00 32.20  ? 162 LYS B C      1 
ATOM   9783  O O      . LYS B 1 162 ? -34.677 35.482  -9.094  1.00 32.96  ? 162 LYS B O      1 
ATOM   9784  C CB     . LYS B 1 162 ? -32.142 36.979  -10.368 1.00 31.13  ? 162 LYS B CB     1 
ATOM   9785  C CG     . LYS B 1 162 ? -31.673 38.271  -10.988 1.00 31.83  ? 162 LYS B CG     1 
ATOM   9786  C CD     . LYS B 1 162 ? -30.894 38.020  -12.267 1.00 32.15  ? 162 LYS B CD     1 
ATOM   9787  C CE     . LYS B 1 162 ? -30.398 39.311  -12.875 1.00 38.39  ? 162 LYS B CE     1 
ATOM   9788  N NZ     . LYS B 1 162 ? -29.323 39.039  -13.850 1.00 44.42  ? 162 LYS B NZ     1 
ATOM   9789  H H      . LYS B 1 162 ? -31.368 37.818  -8.192  1.00 40.17  ? 162 LYS B H      1 
ATOM   9790  H HA     . LYS B 1 162 ? -33.726 37.763  -9.338  1.00 37.38  ? 162 LYS B HA     1 
ATOM   9791  H HB2    . LYS B 1 162 ? -31.357 36.459  -10.137 1.00 37.36  ? 162 LYS B HB2    1 
ATOM   9792  H HB3    . LYS B 1 162 ? -32.667 36.505  -11.032 1.00 37.36  ? 162 LYS B HB3    1 
ATOM   9793  H HG2    . LYS B 1 162 ? -32.442 38.821  -11.203 1.00 38.20  ? 162 LYS B HG2    1 
ATOM   9794  H HG3    . LYS B 1 162 ? -31.093 38.734  -10.364 1.00 38.20  ? 162 LYS B HG3    1 
ATOM   9795  H HD2    . LYS B 1 162 ? -30.126 37.462  -12.070 1.00 38.58  ? 162 LYS B HD2    1 
ATOM   9796  H HD3    . LYS B 1 162 ? -31.471 37.582  -12.912 1.00 38.58  ? 162 LYS B HD3    1 
ATOM   9797  H HE2    . LYS B 1 162 ? -31.128 39.753  -13.337 1.00 46.07  ? 162 LYS B HE2    1 
ATOM   9798  H HE3    . LYS B 1 162 ? -30.042 39.882  -12.176 1.00 46.07  ? 162 LYS B HE3    1 
ATOM   9799  H HZ1    . LYS B 1 162 ? -28.630 38.659  -13.440 1.00 53.30  ? 162 LYS B HZ1    1 
ATOM   9800  H HZ2    . LYS B 1 162 ? -29.620 38.491  -14.485 1.00 53.30  ? 162 LYS B HZ2    1 
ATOM   9801  H HZ3    . LYS B 1 162 ? -29.055 39.798  -14.226 1.00 53.30  ? 162 LYS B HZ3    1 
ATOM   9802  N N      . LEU B 1 163 ? -32.835 35.103  -7.859  1.00 33.83  ? 163 LEU B N      1 
ATOM   9803  C CA     . LEU B 1 163 ? -33.306 33.822  -7.355  1.00 35.45  ? 163 LEU B CA     1 
ATOM   9804  C C      . LEU B 1 163 ? -34.454 34.051  -6.377  1.00 34.17  ? 163 LEU B C      1 
ATOM   9805  O O      . LEU B 1 163 ? -35.459 33.347  -6.414  1.00 33.17  ? 163 LEU B O      1 
ATOM   9806  C CB     . LEU B 1 163 ? -32.169 33.051  -6.676  1.00 34.69  ? 163 LEU B CB     1 
ATOM   9807  C CG     . LEU B 1 163 ? -32.533 31.698  -6.058  1.00 38.26  ? 163 LEU B CG     1 
ATOM   9808  C CD1    . LEU B 1 163 ? -33.229 30.802  -7.060  1.00 35.77  ? 163 LEU B CD1    1 
ATOM   9809  C CD2    . LEU B 1 163 ? -31.286 31.001  -5.507  1.00 36.42  ? 163 LEU B CD2    1 
ATOM   9810  H H      . LEU B 1 163 ? -32.054 35.326  -7.577  1.00 40.59  ? 163 LEU B H      1 
ATOM   9811  H HA     . LEU B 1 163 ? -33.637 33.291  -8.096  1.00 42.54  ? 163 LEU B HA     1 
ATOM   9812  H HB2    . LEU B 1 163 ? -31.477 32.888  -7.336  1.00 41.62  ? 163 LEU B HB2    1 
ATOM   9813  H HB3    . LEU B 1 163 ? -31.810 33.604  -5.965  1.00 41.62  ? 163 LEU B HB3    1 
ATOM   9814  H HG     . LEU B 1 163 ? -33.142 31.845  -5.317  1.00 45.91  ? 163 LEU B HG     1 
ATOM   9815  H HD11   . LEU B 1 163 ? -33.385 29.939  -6.648  1.00 42.92  ? 163 LEU B HD11   1 
ATOM   9816  H HD12   . LEU B 1 163 ? -34.075 31.203  -7.313  1.00 42.92  ? 163 LEU B HD12   1 
ATOM   9817  H HD13   . LEU B 1 163 ? -32.662 30.700  -7.841  1.00 42.92  ? 163 LEU B HD13   1 
ATOM   9818  H HD21   . LEU B 1 163 ? -31.562 30.262  -4.942  1.00 43.70  ? 163 LEU B HD21   1 
ATOM   9819  H HD22   . LEU B 1 163 ? -30.756 30.670  -6.249  1.00 43.70  ? 163 LEU B HD22   1 
ATOM   9820  H HD23   . LEU B 1 163 ? -30.769 31.638  -4.990  1.00 43.70  ? 163 LEU B HD23   1 
ATOM   9821  N N      . GLU B 1 164 ? -34.298 35.042  -5.508  1.00 35.39  ? 164 GLU B N      1 
ATOM   9822  C CA     . GLU B 1 164 ? -35.355 35.392  -4.562  1.00 41.76  ? 164 GLU B CA     1 
ATOM   9823  C C      . GLU B 1 164 ? -36.615 35.819  -5.313  1.00 36.37  ? 164 GLU B C      1 
ATOM   9824  O O      . GLU B 1 164 ? -37.718 35.395  -4.970  1.00 41.89  ? 164 GLU B O      1 
ATOM   9825  C CB     . GLU B 1 164 ? -34.887 36.497  -3.611  1.00 36.27  ? 164 GLU B CB     1 
ATOM   9826  C CG     . GLU B 1 164 ? -34.186 35.959  -2.375  1.00 39.80  ? 164 GLU B CG     1 
ATOM   9827  C CD     . GLU B 1 164 ? -33.624 37.040  -1.472  1.00 56.87  ? 164 GLU B CD     1 
ATOM   9828  O OE1    . GLU B 1 164 ? -33.425 38.180  -1.947  1.00 57.00  ? 164 GLU B OE1    1 
ATOM   9829  O OE2    . GLU B 1 164 ? -33.373 36.742  -0.282  1.00 59.49  ? 164 GLU B OE2    1 
ATOM   9830  H H      . GLU B 1 164 ? -33.591 35.528  -5.444  1.00 42.47  ? 164 GLU B H      1 
ATOM   9831  H HA     . GLU B 1 164 ? -35.574 34.611  -4.030  1.00 50.11  ? 164 GLU B HA     1 
ATOM   9832  H HB2    . GLU B 1 164 ? -34.265 37.073  -4.082  1.00 43.53  ? 164 GLU B HB2    1 
ATOM   9833  H HB3    . GLU B 1 164 ? -35.657 37.009  -3.319  1.00 43.53  ? 164 GLU B HB3    1 
ATOM   9834  H HG2    . GLU B 1 164 ? -34.818 35.436  -1.857  1.00 47.76  ? 164 GLU B HG2    1 
ATOM   9835  H HG3    . GLU B 1 164 ? -33.447 35.400  -2.657  1.00 47.76  ? 164 GLU B HG3    1 
ATOM   9836  N N      . LYS B 1 165 ? -36.443 36.637  -6.347  1.00 37.58  ? 165 LYS B N      1 
ATOM   9837  C CA     . LYS B 1 165 ? -37.565 37.080  -7.177  1.00 40.47  ? 165 LYS B CA     1 
ATOM   9838  C C      . LYS B 1 165 ? -38.295 35.900  -7.804  1.00 42.83  ? 165 LYS B C      1 
ATOM   9839  O O      . LYS B 1 165 ? -39.525 35.856  -7.822  1.00 45.02  ? 165 LYS B O      1 
ATOM   9840  C CB     . LYS B 1 165 ? -37.077 38.029  -8.275  1.00 46.44  ? 165 LYS B CB     1 
ATOM   9841  C CG     . LYS B 1 165 ? -38.159 38.485  -9.251  1.00 54.74  ? 165 LYS B CG     1 
ATOM   9842  C CD     . LYS B 1 165 ? -37.601 39.472  -10.270 1.00 57.28  ? 165 LYS B CD     1 
ATOM   9843  C CE     . LYS B 1 165 ? -38.694 40.061  -11.156 1.00 72.38  ? 165 LYS B CE     1 
ATOM   9844  N NZ     . LYS B 1 165 ? -39.442 39.013  -11.903 1.00 92.20  ? 165 LYS B NZ     1 
ATOM   9845  H H      . LYS B 1 165 ? -35.682 36.953  -6.592  1.00 45.10  ? 165 LYS B H      1 
ATOM   9846  H HA     . LYS B 1 165 ? -38.197 37.563  -6.622  1.00 48.57  ? 165 LYS B HA     1 
ATOM   9847  H HB2    . LYS B 1 165 ? -36.706 38.822  -7.857  1.00 55.73  ? 165 LYS B HB2    1 
ATOM   9848  H HB3    . LYS B 1 165 ? -36.388 37.579  -8.789  1.00 55.73  ? 165 LYS B HB3    1 
ATOM   9849  H HG2    . LYS B 1 165 ? -38.505 37.718  -9.734  1.00 65.69  ? 165 LYS B HG2    1 
ATOM   9850  H HG3    . LYS B 1 165 ? -38.871 38.923  -8.760  1.00 65.69  ? 165 LYS B HG3    1 
ATOM   9851  H HD2    . LYS B 1 165 ? -37.166 40.202  -9.801  1.00 68.73  ? 165 LYS B HD2    1 
ATOM   9852  H HD3    . LYS B 1 165 ? -36.964 39.014  -10.840 1.00 68.73  ? 165 LYS B HD3    1 
ATOM   9853  H HE2    . LYS B 1 165 ? -39.326 40.545  -10.601 1.00 86.86  ? 165 LYS B HE2    1 
ATOM   9854  H HE3    . LYS B 1 165 ? -38.290 40.661  -11.802 1.00 86.86  ? 165 LYS B HE3    1 
ATOM   9855  H HZ1    . LYS B 1 165 ? -38.908 38.629  -12.503 1.00 110.64 ? 165 LYS B HZ1    1 
ATOM   9856  H HZ2    . LYS B 1 165 ? -39.738 38.391  -11.340 1.00 110.64 ? 165 LYS B HZ2    1 
ATOM   9857  H HZ3    . LYS B 1 165 ? -40.136 39.377  -12.325 1.00 110.64 ? 165 LYS B HZ3    1 
ATOM   9858  N N      . LEU B 1 166 ? -37.531 34.947  -8.326  1.00 41.26  ? 166 LEU B N      1 
ATOM   9859  C CA     . LEU B 1 166 ? -38.111 33.762  -8.939  1.00 37.56  ? 166 LEU B CA     1 
ATOM   9860  C C      . LEU B 1 166 ? -38.941 32.958  -7.943  1.00 36.42  ? 166 LEU B C      1 
ATOM   9861  O O      . LEU B 1 166 ? -40.047 32.526  -8.255  1.00 38.19  ? 166 LEU B O      1 
ATOM   9862  C CB     . LEU B 1 166 ? -37.011 32.877  -9.527  1.00 40.93  ? 166 LEU B CB     1 
ATOM   9863  C CG     . LEU B 1 166 ? -37.488 31.588  -10.195 1.00 42.89  ? 166 LEU B CG     1 
ATOM   9864  C CD1    . LEU B 1 166 ? -38.280 31.902  -11.462 1.00 40.88  ? 166 LEU B CD1    1 
ATOM   9865  C CD2    . LEU B 1 166 ? -36.302 30.689  -10.498 1.00 42.52  ? 166 LEU B CD2    1 
ATOM   9866  H H      . LEU B 1 166 ? -36.671 34.964  -8.337  1.00 49.51  ? 166 LEU B H      1 
ATOM   9867  H HA     . LEU B 1 166 ? -38.695 34.037  -9.663  1.00 45.07  ? 166 LEU B HA     1 
ATOM   9868  H HB2    . LEU B 1 166 ? -36.530 33.390  -10.195 1.00 49.12  ? 166 LEU B HB2    1 
ATOM   9869  H HB3    . LEU B 1 166 ? -36.404 32.627  -8.813  1.00 49.12  ? 166 LEU B HB3    1 
ATOM   9870  H HG     . LEU B 1 166 ? -38.073 31.107  -9.589  1.00 51.47  ? 166 LEU B HG     1 
ATOM   9871  H HD11   . LEU B 1 166 ? -38.523 31.069  -11.896 1.00 49.05  ? 166 LEU B HD11   1 
ATOM   9872  H HD12   . LEU B 1 166 ? -39.080 32.395  -11.221 1.00 49.05  ? 166 LEU B HD12   1 
ATOM   9873  H HD13   . LEU B 1 166 ? -37.728 32.435  -12.055 1.00 49.05  ? 166 LEU B HD13   1 
ATOM   9874  H HD21   . LEU B 1 166 ? -36.622 29.878  -10.924 1.00 51.02  ? 166 LEU B HD21   1 
ATOM   9875  H HD22   . LEU B 1 166 ? -35.695 31.158  -11.092 1.00 51.02  ? 166 LEU B HD22   1 
ATOM   9876  H HD23   . LEU B 1 166 ? -35.851 30.471  -9.667  1.00 51.02  ? 166 LEU B HD23   1 
ATOM   9877  N N      . ILE B 1 167 ? -38.402 32.744  -6.750  1.00 36.51  ? 167 ILE B N      1 
ATOM   9878  C CA     . ILE B 1 167 ? -39.099 31.939  -5.753  1.00 43.68  ? 167 ILE B CA     1 
ATOM   9879  C C      . ILE B 1 167 ? -40.428 32.598  -5.381  1.00 45.46  ? 167 ILE B C      1 
ATOM   9880  O O      . ILE B 1 167 ? -41.454 31.927  -5.272  1.00 40.27  ? 167 ILE B O      1 
ATOM   9881  C CB     . ILE B 1 167 ? -38.241 31.730  -4.482  1.00 41.85  ? 167 ILE B CB     1 
ATOM   9882  C CG1    . ILE B 1 167 ? -36.991 30.912  -4.821  1.00 38.98  ? 167 ILE B CG1    1 
ATOM   9883  C CG2    . ILE B 1 167 ? -39.038 30.999  -3.403  1.00 40.05  ? 167 ILE B CG2    1 
ATOM   9884  C CD1    . ILE B 1 167 ? -35.968 30.842  -3.700  1.00 43.30  ? 167 ILE B CD1    1 
ATOM   9885  H H      . ILE B 1 167 ? -37.641 33.050  -6.493  1.00 43.82  ? 167 ILE B H      1 
ATOM   9886  H HA     . ILE B 1 167 ? -39.292 31.067  -6.131  1.00 52.42  ? 167 ILE B HA     1 
ATOM   9887  H HB     . ILE B 1 167 ? -37.968 32.596  -4.140  1.00 50.22  ? 167 ILE B HB     1 
ATOM   9888  H HG12   . ILE B 1 167 ? -37.263 30.004  -5.025  1.00 46.78  ? 167 ILE B HG12   1 
ATOM   9889  H HG13   . ILE B 1 167 ? -36.558 31.302  -5.595  1.00 46.78  ? 167 ILE B HG13   1 
ATOM   9890  H HG21   . ILE B 1 167 ? -38.436 30.712  -2.700  1.00 48.06  ? 167 ILE B HG21   1 
ATOM   9891  H HG22   . ILE B 1 167 ? -39.704 31.601  -3.035  1.00 48.06  ? 167 ILE B HG22   1 
ATOM   9892  H HG23   . ILE B 1 167 ? -39.471 30.228  -3.800  1.00 48.06  ? 167 ILE B HG23   1 
ATOM   9893  H HD11   . ILE B 1 167 ? -35.127 30.521  -4.061  1.00 51.96  ? 167 ILE B HD11   1 
ATOM   9894  H HD12   . ILE B 1 167 ? -35.850 31.729  -3.326  1.00 51.96  ? 167 ILE B HD12   1 
ATOM   9895  H HD13   . ILE B 1 167 ? -36.288 30.234  -3.015  1.00 51.96  ? 167 ILE B HD13   1 
ATOM   9896  N N      . ALA B 1 168 ? -40.402 33.914  -5.203  1.00 47.28  ? 168 ALA B N      1 
ATOM   9897  C CA     . ALA B 1 168 ? -41.599 34.658  -4.835  1.00 44.68  ? 168 ALA B CA     1 
ATOM   9898  C C      . ALA B 1 168 ? -42.640 34.623  -5.955  1.00 44.02  ? 168 ALA B C      1 
ATOM   9899  O O      . ALA B 1 168 ? -43.823 34.412  -5.700  1.00 46.93  ? 168 ALA B O      1 
ATOM   9900  C CB     . ALA B 1 168 ? -41.236 36.089  -4.487  1.00 39.63  ? 168 ALA B CB     1 
ATOM   9901  H H      . ALA B 1 168 ? -39.699 34.402  -5.290  1.00 56.73  ? 168 ALA B H      1 
ATOM   9902  H HA     . ALA B 1 168 ? -41.993 34.250  -4.048  1.00 53.61  ? 168 ALA B HA     1 
ATOM   9903  H HB1    . ALA B 1 168 ? -42.043 36.569  -4.245  1.00 47.55  ? 168 ALA B HB1    1 
ATOM   9904  H HB2    . ALA B 1 168 ? -40.617 36.085  -3.740  1.00 47.55  ? 168 ALA B HB2    1 
ATOM   9905  H HB3    . ALA B 1 168 ? -40.822 36.506  -5.259  1.00 47.55  ? 168 ALA B HB3    1 
ATOM   9906  N N      . GLU B 1 169 ? -42.197 34.808  -7.195  1.00 45.61  ? 169 GLU B N      1 
ATOM   9907  C CA     . GLU B 1 169 ? -43.114 34.873  -8.333  1.00 42.96  ? 169 GLU B CA     1 
ATOM   9908  C C      . GLU B 1 169 ? -43.676 33.519  -8.754  1.00 47.31  ? 169 GLU B C      1 
ATOM   9909  O O      . GLU B 1 169 ? -44.821 33.434  -9.193  1.00 49.84  ? 169 GLU B O      1 
ATOM   9910  C CB     . GLU B 1 169 ? -42.422 35.509  -9.542  1.00 52.01  ? 169 GLU B CB     1 
ATOM   9911  C CG     . GLU B 1 169 ? -42.606 37.015  -9.648  1.00 59.54  ? 169 GLU B CG     1 
ATOM   9912  C CD     . GLU B 1 169 ? -42.110 37.572  -10.972 1.00 83.62  ? 169 GLU B CD     1 
ATOM   9913  O OE1    . GLU B 1 169 ? -41.678 36.775  -11.835 1.00 76.88  ? 169 GLU B OE1    1 
ATOM   9914  O OE2    . GLU B 1 169 ? -42.149 38.809  -11.147 1.00 83.91  ? 169 GLU B OE2    1 
ATOM   9915  H H      . GLU B 1 169 ? -41.368 34.899  -7.406  1.00 54.74  ? 169 GLU B H      1 
ATOM   9916  H HA     . GLU B 1 169 ? -43.864 35.439  -8.093  1.00 51.55  ? 169 GLU B HA     1 
ATOM   9917  H HB2    . GLU B 1 169 ? -41.470 35.330  -9.488  1.00 62.41  ? 169 GLU B HB2    1 
ATOM   9918  H HB3    . GLU B 1 169 ? -42.786 35.108  -10.347 1.00 62.41  ? 169 GLU B HB3    1 
ATOM   9919  H HG2    . GLU B 1 169 ? -43.550 37.225  -9.569  1.00 71.45  ? 169 GLU B HG2    1 
ATOM   9920  H HG3    . GLU B 1 169 ? -42.108 37.446  -8.935  1.00 71.45  ? 169 GLU B HG3    1 
ATOM   9921  N N      . LYS B 1 170 ? -42.874 32.464  -8.638  1.00 41.86  ? 170 LYS B N      1 
ATOM   9922  C CA     . LYS B 1 170 ? -43.268 31.158  -9.160  1.00 41.48  ? 170 LYS B CA     1 
ATOM   9923  C C      . LYS B 1 170 ? -43.622 30.165  -8.063  1.00 35.76  ? 170 LYS B C      1 
ATOM   9924  O O      . LYS B 1 170 ? -44.332 29.193  -8.311  1.00 42.89  ? 170 LYS B O      1 
ATOM   9925  C CB     . LYS B 1 170 ? -42.153 30.581  -10.033 1.00 43.61  ? 170 LYS B CB     1 
ATOM   9926  C CG     . LYS B 1 170 ? -42.353 30.808  -11.526 1.00 48.50  ? 170 LYS B CG     1 
ATOM   9927  C CD     . LYS B 1 170 ? -42.243 32.269  -11.905 1.00 52.11  ? 170 LYS B CD     1 
ATOM   9928  C CE     . LYS B 1 170 ? -42.442 32.466  -13.402 1.00 47.98  ? 170 LYS B CE     1 
ATOM   9929  N NZ     . LYS B 1 170 ? -42.170 33.872  -13.813 1.00 71.64  ? 170 LYS B NZ     1 
ATOM   9930  H H      . LYS B 1 170 ? -42.100 32.477  -8.263  1.00 50.24  ? 170 LYS B H      1 
ATOM   9931  H HA     . LYS B 1 170 ? -44.049 31.256  -9.725  1.00 49.78  ? 170 LYS B HA     1 
ATOM   9932  H HB2    . LYS B 1 170 ? -41.313 30.994  -9.782  1.00 52.34  ? 170 LYS B HB2    1 
ATOM   9933  H HB3    . LYS B 1 170 ? -42.105 29.624  -9.884  1.00 52.34  ? 170 LYS B HB3    1 
ATOM   9934  H HG2    . LYS B 1 170 ? -41.667 30.324  -12.011 1.00 58.20  ? 170 LYS B HG2    1 
ATOM   9935  H HG3    . LYS B 1 170 ? -43.233 30.492  -11.784 1.00 58.20  ? 170 LYS B HG3    1 
ATOM   9936  H HD2    . LYS B 1 170 ? -42.926 32.775  -11.438 1.00 62.54  ? 170 LYS B HD2    1 
ATOM   9937  H HD3    . LYS B 1 170 ? -41.361 32.597  -11.669 1.00 62.54  ? 170 LYS B HD3    1 
ATOM   9938  H HE2    . LYS B 1 170 ? -41.833 31.886  -13.884 1.00 57.58  ? 170 LYS B HE2    1 
ATOM   9939  H HE3    . LYS B 1 170 ? -43.360 32.255  -13.633 1.00 57.58  ? 170 LYS B HE3    1 
ATOM   9940  H HZ1    . LYS B 1 170 ? -42.293 33.961  -14.690 1.00 85.97  ? 170 LYS B HZ1    1 
ATOM   9941  H HZ2    . LYS B 1 170 ? -42.721 34.425  -13.386 1.00 85.97  ? 170 LYS B HZ2    1 
ATOM   9942  H HZ3    . LYS B 1 170 ? -41.330 34.090  -13.615 1.00 85.97  ? 170 LYS B HZ3    1 
ATOM   9943  N N      . GLY B 1 171 ? -43.133 30.409  -6.854  1.00 38.61  ? 171 GLY B N      1 
ATOM   9944  C CA     . GLY B 1 171 ? -43.333 29.480  -5.758  1.00 43.19  ? 171 GLY B CA     1 
ATOM   9945  C C      . GLY B 1 171 ? -42.284 28.384  -5.767  1.00 45.35  ? 171 GLY B C      1 
ATOM   9946  O O      . GLY B 1 171 ? -41.926 27.859  -6.824  1.00 42.19  ? 171 GLY B O      1 
ATOM   9947  H H      . GLY B 1 171 ? -42.680 31.109  -6.643  1.00 46.33  ? 171 GLY B H      1 
ATOM   9948  H HA2    . GLY B 1 171 ? -43.275 29.956  -4.915  1.00 51.83  ? 171 GLY B HA2    1 
ATOM   9949  H HA3    . GLY B 1 171 ? -44.211 29.073  -5.823  1.00 51.83  ? 171 GLY B HA3    1 
ATOM   9950  N N      . ALA B 1 172 ? -41.794 28.045  -4.580  1.00 41.20  ? 172 ALA B N      1 
ATOM   9951  C CA     . ALA B 1 172 ? -40.735 27.053  -4.423  1.00 43.46  ? 172 ALA B CA     1 
ATOM   9952  C C      . ALA B 1 172 ? -41.107 25.702  -5.025  1.00 43.24  ? 172 ALA B C      1 
ATOM   9953  O O      . ALA B 1 172 ? -40.282 25.065  -5.678  1.00 42.77  ? 172 ALA B O      1 
ATOM   9954  C CB     . ALA B 1 172 ? -40.391 26.888  -2.948  1.00 39.83  ? 172 ALA B CB     1 
ATOM   9955  H H      . ALA B 1 172 ? -42.063 28.382  -3.836  1.00 49.43  ? 172 ALA B H      1 
ATOM   9956  H HA     . ALA B 1 172 ? -39.940 27.371  -4.879  1.00 52.16  ? 172 ALA B HA     1 
ATOM   9957  H HB1    . ALA B 1 172 ? -39.684 26.230  -2.861  1.00 47.79  ? 172 ALA B HB1    1 
ATOM   9958  H HB2    . ALA B 1 172 ? -40.094 27.742  -2.596  1.00 47.79  ? 172 ALA B HB2    1 
ATOM   9959  H HB3    . ALA B 1 172 ? -41.182 26.590  -2.471  1.00 47.79  ? 172 ALA B HB3    1 
ATOM   9960  N N      . GLU B 1 173 ? -42.349 25.273  -4.817  1.00 48.48  ? 173 GLU B N      1 
ATOM   9961  C CA     . GLU B 1 173 ? -42.782 23.946  -5.255  1.00 45.35  ? 173 GLU B CA     1 
ATOM   9962  C C      . GLU B 1 173 ? -42.788 23.801  -6.780  1.00 43.56  ? 173 GLU B C      1 
ATOM   9963  O O      . GLU B 1 173 ? -42.871 22.687  -7.301  1.00 42.53  ? 173 GLU B O      1 
ATOM   9964  C CB     . GLU B 1 173 ? -44.177 23.619  -4.697  1.00 47.02  ? 173 GLU B CB     1 
ATOM   9965  C CG     . GLU B 1 173 ? -45.339 24.430  -5.285  1.00 54.84  ? 173 GLU B CG     1 
ATOM   9966  C CD     . GLU B 1 173 ? -45.539 25.784  -4.615  1.00 68.99  ? 173 GLU B CD     1 
ATOM   9967  O OE1    . GLU B 1 173 ? -44.706 26.175  -3.766  1.00 64.75  ? 173 GLU B OE1    1 
ATOM   9968  O OE2    . GLU B 1 173 ? -46.541 26.458  -4.940  1.00 70.19  ? 173 GLU B OE2    1 
ATOM   9969  H H      . GLU B 1 173 ? -42.961 25.731  -4.423  1.00 58.18  ? 173 GLU B H      1 
ATOM   9970  H HA     . GLU B 1 173 ? -42.163 23.288  -4.901  1.00 54.41  ? 173 GLU B HA     1 
ATOM   9971  H HB2    . GLU B 1 173 ? -44.362 22.684  -4.876  1.00 56.42  ? 173 GLU B HB2    1 
ATOM   9972  H HB3    . GLU B 1 173 ? -44.168 23.764  -3.738  1.00 56.42  ? 173 GLU B HB3    1 
ATOM   9973  H HG2    . GLU B 1 173 ? -45.184 24.587  -6.229  1.00 65.81  ? 173 GLU B HG2    1 
ATOM   9974  H HG3    . GLU B 1 173 ? -46.158 23.923  -5.170  1.00 65.81  ? 173 GLU B HG3    1 
ATOM   9975  N N      . ASN B 1 174 ? -42.698 24.921  -7.490  1.00 37.53  ? 174 ASN B N      1 
ATOM   9976  C CA     . ASN B 1 174 ? -42.704 24.908  -8.949  1.00 41.79  ? 174 ASN B CA     1 
ATOM   9977  C C      . ASN B 1 174 ? -41.300 24.957  -9.551  1.00 39.43  ? 174 ASN B C      1 
ATOM   9978  O O      . ASN B 1 174 ? -41.138 24.933  -10.774 1.00 36.21  ? 174 ASN B O      1 
ATOM   9979  C CB     . ASN B 1 174 ? -43.530 26.079  -9.472  1.00 42.47  ? 174 ASN B CB     1 
ATOM   9980  C CG     . ASN B 1 174 ? -45.001 25.928  -9.158  1.00 49.86  ? 174 ASN B CG     1 
ATOM   9981  O OD1    . ASN B 1 174 ? -45.554 24.831  -9.241  1.00 47.12  ? 174 ASN B OD1    1 
ATOM   9982  N ND2    . ASN B 1 174 ? -45.643 27.030  -8.783  1.00 53.73  ? 174 ASN B ND2    1 
ATOM   9983  H H      . ASN B 1 174 ? -42.633 25.708  -7.150  1.00 45.03  ? 174 ASN B H      1 
ATOM   9984  H HA     . ASN B 1 174 ? -43.126 24.093  -9.260  1.00 50.15  ? 174 ASN B HA     1 
ATOM   9985  H HB2    . ASN B 1 174 ? -43.216 26.899  -9.059  1.00 50.96  ? 174 ASN B HB2    1 
ATOM   9986  H HB3    . ASN B 1 174 ? -43.432 26.132  -10.436 1.00 50.96  ? 174 ASN B HB3    1 
ATOM   9987  H HD21   . ASN B 1 174 ? -46.461 26.983  -8.520  1.00 64.47  ? 174 ASN B HD21   1 
ATOM   9988  H HD22   . ASN B 1 174 ? -45.241 27.789  -8.803  1.00 64.47  ? 174 ASN B HD22   1 
ATOM   9989  N N      . ILE B 1 175 ? -40.298 25.024  -8.680  1.00 39.30  ? 175 ILE B N      1 
ATOM   9990  C CA     . ILE B 1 175 ? -38.901 25.027  -9.092  1.00 36.47  ? 175 ILE B CA     1 
ATOM   9991  C C      . ILE B 1 175 ? -38.330 23.625  -8.898  1.00 36.30  ? 175 ILE B C      1 
ATOM   9992  O O      . ILE B 1 175 ? -38.218 23.138  -7.771  1.00 32.70  ? 175 ILE B O      1 
ATOM   9993  C CB     . ILE B 1 175 ? -38.087 26.069  -8.297  1.00 37.14  ? 175 ILE B CB     1 
ATOM   9994  C CG1    . ILE B 1 175 ? -38.659 27.472  -8.552  1.00 39.61  ? 175 ILE B CG1    1 
ATOM   9995  C CG2    . ILE B 1 175 ? -36.612 26.022  -8.691  1.00 32.84  ? 175 ILE B CG2    1 
ATOM   9996  C CD1    . ILE B 1 175 ? -38.068 28.559  -7.680  1.00 45.35  ? 175 ILE B CD1    1 
ATOM   9997  H H      . ILE B 1 175 ? -40.402 25.070  -7.828  1.00 47.16  ? 175 ILE B H      1 
ATOM   9998  H HA     . ILE B 1 175 ? -38.836 25.253  -10.033 1.00 43.76  ? 175 ILE B HA     1 
ATOM   9999  H HB     . ILE B 1 175 ? -38.163 25.868  -7.351  1.00 44.57  ? 175 ILE B HB     1 
ATOM   10000 H HG12   . ILE B 1 175 ? -38.490 27.712  -9.476  1.00 47.54  ? 175 ILE B HG12   1 
ATOM   10001 H HG13   . ILE B 1 175 ? -39.615 27.455  -8.389  1.00 47.54  ? 175 ILE B HG13   1 
ATOM   10002 H HG21   . ILE B 1 175 ? -36.143 26.753  -8.259  1.00 39.41  ? 175 ILE B HG21   1 
ATOM   10003 H HG22   . ILE B 1 175 ? -36.232 25.177  -8.405  1.00 39.41  ? 175 ILE B HG22   1 
ATOM   10004 H HG23   . ILE B 1 175 ? -36.541 26.108  -9.655  1.00 39.41  ? 175 ILE B HG23   1 
ATOM   10005 H HD11   . ILE B 1 175 ? -38.601 29.364  -7.776  1.00 54.42  ? 175 ILE B HD11   1 
ATOM   10006 H HD12   . ILE B 1 175 ? -38.080 28.263  -6.756  1.00 54.42  ? 175 ILE B HD12   1 
ATOM   10007 H HD13   . ILE B 1 175 ? -37.156 28.731  -7.961  1.00 54.42  ? 175 ILE B HD13   1 
ATOM   10008 N N      . ALA B 1 176 ? -37.992 22.975  -10.010 1.00 35.83  ? 176 ALA B N      1 
ATOM   10009 C CA     . ALA B 1 176 ? -37.443 21.619  -9.979  1.00 38.07  ? 176 ALA B CA     1 
ATOM   10010 C C      . ALA B 1 176 ? -36.100 21.593  -9.252  1.00 29.15  ? 176 ALA B C      1 
ATOM   10011 O O      . ALA B 1 176 ? -35.915 20.844  -8.290  1.00 29.27  ? 176 ALA B O      1 
ATOM   10012 C CB     . ALA B 1 176 ? -37.298 21.075  -11.395 1.00 32.00  ? 176 ALA B CB     1 
ATOM   10013 H H      . ALA B 1 176 ? -38.071 23.300  -10.802 1.00 43.00  ? 176 ALA B H      1 
ATOM   10014 H HA     . ALA B 1 176 ? -38.056 21.041  -9.497  1.00 45.68  ? 176 ALA B HA     1 
ATOM   10015 H HB1    . ALA B 1 176 ? -36.929 20.179  -11.352 1.00 38.40  ? 176 ALA B HB1    1 
ATOM   10016 H HB2    . ALA B 1 176 ? -38.172 21.054  -11.816 1.00 38.40  ? 176 ALA B HB2    1 
ATOM   10017 H HB3    . ALA B 1 176 ? -36.703 21.655  -11.896 1.00 38.40  ? 176 ALA B HB3    1 
ATOM   10018 N N      . TYR B 1 177 ? -35.162 22.410  -9.718  1.00 30.08  ? 177 TYR B N      1 
ATOM   10019 C CA     . TYR B 1 177 ? -33.909 22.605  -9.006  1.00 29.23  ? 177 TYR B CA     1 
ATOM   10020 C C      . TYR B 1 177 ? -33.145 23.803  -9.536  1.00 28.77  ? 177 TYR B C      1 
ATOM   10021 O O      . TYR B 1 177 ? -33.467 24.355  -10.590 1.00 28.68  ? 177 TYR B O      1 
ATOM   10022 C CB     . TYR B 1 177 ? -33.021 21.353  -9.084  1.00 29.11  ? 177 TYR B CB     1 
ATOM   10023 C CG     . TYR B 1 177 ? -32.683 20.842  -10.476 1.00 30.11  ? 177 TYR B CG     1 
ATOM   10024 C CD1    . TYR B 1 177 ? -31.555 21.298  -11.158 1.00 27.70  ? 177 TYR B CD1    1 
ATOM   10025 C CD2    . TYR B 1 177 ? -33.463 19.864  -11.085 1.00 30.72  ? 177 TYR B CD2    1 
ATOM   10026 C CE1    . TYR B 1 177 ? -31.232 20.812  -12.421 1.00 28.81  ? 177 TYR B CE1    1 
ATOM   10027 C CE2    . TYR B 1 177 ? -33.149 19.376  -12.345 1.00 34.44  ? 177 TYR B CE2    1 
ATOM   10028 C CZ     . TYR B 1 177 ? -32.034 19.851  -13.008 1.00 29.15  ? 177 TYR B CZ     1 
ATOM   10029 O OH     . TYR B 1 177 ? -31.724 19.354  -14.255 1.00 30.12  ? 177 TYR B OH     1 
ATOM   10030 H H      . TYR B 1 177 ? -35.228 22.863  -10.446 1.00 36.09  ? 177 TYR B H      1 
ATOM   10031 H HA     . TYR B 1 177 ? -34.105 22.770  -8.071  1.00 35.07  ? 177 TYR B HA     1 
ATOM   10032 H HB2    . TYR B 1 177 ? -32.180 21.552  -8.643  1.00 34.93  ? 177 TYR B HB2    1 
ATOM   10033 H HB3    . TYR B 1 177 ? -33.463 20.631  -8.612  1.00 34.93  ? 177 TYR B HB3    1 
ATOM   10034 H HD1    . TYR B 1 177 ? -31.014 21.945  -10.765 1.00 33.24  ? 177 TYR B HD1    1 
ATOM   10035 H HD2    . TYR B 1 177 ? -34.215 19.540  -10.644 1.00 36.86  ? 177 TYR B HD2    1 
ATOM   10036 H HE1    . TYR B 1 177 ? -30.481 21.131  -12.867 1.00 34.57  ? 177 TYR B HE1    1 
ATOM   10037 H HE2    . TYR B 1 177 ? -33.685 18.727  -12.741 1.00 41.32  ? 177 TYR B HE2    1 
ATOM   10038 H HH     . TYR B 1 177 ? -31.047 19.746  -14.560 1.00 36.14  ? 177 TYR B HH     1 
ATOM   10039 N N      . ILE B 1 178 ? -32.145 24.213  -8.767  1.00 26.55  ? 178 ILE B N      1 
ATOM   10040 C CA     . ILE B 1 178 ? -31.178 25.191  -9.225  1.00 29.25  ? 178 ILE B CA     1 
ATOM   10041 C C      . ILE B 1 178 ? -30.025 24.434  -9.871  1.00 29.69  ? 178 ILE B C      1 
ATOM   10042 O O      . ILE B 1 178 ? -29.497 23.490  -9.283  1.00 29.88  ? 178 ILE B O      1 
ATOM   10043 C CB     . ILE B 1 178 ? -30.650 26.065  -8.076  1.00 29.68  ? 178 ILE B CB     1 
ATOM   10044 C CG1    . ILE B 1 178 ? -31.809 26.735  -7.325  1.00 31.55  ? 178 ILE B CG1    1 
ATOM   10045 C CG2    . ILE B 1 178 ? -29.655 27.101  -8.604  1.00 28.31  ? 178 ILE B CG2    1 
ATOM   10046 C CD1    . ILE B 1 178 ? -32.707 27.599  -8.195  1.00 34.23  ? 178 ILE B CD1    1 
ATOM   10047 H H      . ILE B 1 178 ? -32.006 23.934  -7.966  1.00 31.86  ? 178 ILE B H      1 
ATOM   10048 H HA     . ILE B 1 178 ? -31.581 25.767  -9.891  1.00 35.11  ? 178 ILE B HA     1 
ATOM   10049 H HB     . ILE B 1 178 ? -30.181 25.489  -7.453  1.00 35.62  ? 178 ILE B HB     1 
ATOM   10050 H HG12   . ILE B 1 178 ? -32.361 26.047  -6.922  1.00 37.86  ? 178 ILE B HG12   1 
ATOM   10051 H HG13   . ILE B 1 178 ? -31.439 27.305  -6.633  1.00 37.86  ? 178 ILE B HG13   1 
ATOM   10052 H HG21   . ILE B 1 178 ? -29.474 27.747  -7.904  1.00 33.98  ? 178 ILE B HG21   1 
ATOM   10053 H HG22   . ILE B 1 178 ? -28.834 26.653  -8.860  1.00 33.98  ? 178 ILE B HG22   1 
ATOM   10054 H HG23   . ILE B 1 178 ? -30.043 27.548  -9.373  1.00 33.98  ? 178 ILE B HG23   1 
ATOM   10055 H HD11   . ILE B 1 178 ? -33.408 27.976  -7.642  1.00 41.07  ? 178 ILE B HD11   1 
ATOM   10056 H HD12   . ILE B 1 178 ? -32.177 28.309  -8.590  1.00 41.07  ? 178 ILE B HD12   1 
ATOM   10057 H HD13   . ILE B 1 178 ? -33.101 27.052  -8.892  1.00 41.07  ? 178 ILE B HD13   1 
ATOM   10058 N N      . CYS B 1 179 ? -29.663 24.837  -11.083 1.00 27.47  ? 179 CYS B N      1 
ATOM   10059 C CA     . CYS B 1 179 ? -28.533 24.248  -11.796 1.00 30.14  ? 179 CYS B CA     1 
ATOM   10060 C C      . CYS B 1 179 ? -27.349 25.203  -11.727 1.00 27.90  ? 179 CYS B C      1 
ATOM   10061 O O      . CYS B 1 179 ? -27.302 26.201  -12.446 1.00 26.21  ? 179 CYS B O      1 
ATOM   10062 C CB     . CYS B 1 179 ? -28.905 23.947  -13.247 1.00 27.92  ? 179 CYS B CB     1 
ATOM   10063 S SG     . CYS B 1 179 ? -27.653 22.958  -14.142 1.00 34.32  ? 179 CYS B SG     1 
ATOM   10064 H H      . CYS B 1 179 ? -30.062 25.460  -11.522 1.00 32.96  ? 179 CYS B H      1 
ATOM   10065 H HA     . CYS B 1 179 ? -28.277 23.414  -11.376 1.00 36.16  ? 179 CYS B HA     1 
ATOM   10066 H HB2    . CYS B 1 179 ? -29.738 23.449  -13.258 1.00 33.51  ? 179 CYS B HB2    1 
ATOM   10067 H HB3    . CYS B 1 179 ? -29.018 24.785  -13.723 1.00 33.51  ? 179 CYS B HB3    1 
ATOM   10068 H HG     . CYS B 1 179 ? -28.027 22.776  -15.268 1.00 41.19  ? 179 CYS B HG     1 
ATOM   10069 N N      . LEU B 1 180 ? -26.409 24.907  -10.835 1.00 24.63  ? 180 LEU B N      1 
ATOM   10070 C CA     . LEU B 1 180 ? -25.249 25.771  -10.628 1.00 25.44  ? 180 LEU B CA     1 
ATOM   10071 C C      . LEU B 1 180 ? -24.045 25.205  -11.367 1.00 27.12  ? 180 LEU B C      1 
ATOM   10072 O O      . LEU B 1 180 ? -23.515 24.164  -10.998 1.00 24.27  ? 180 LEU B O      1 
ATOM   10073 C CB     . LEU B 1 180 ? -24.944 25.911  -9.135  1.00 23.90  ? 180 LEU B CB     1 
ATOM   10074 C CG     . LEU B 1 180 ? -24.021 27.050  -8.701  1.00 27.16  ? 180 LEU B CG     1 
ATOM   10075 C CD1    . LEU B 1 180 ? -24.321 27.447  -7.261  1.00 25.58  ? 180 LEU B CD1    1 
ATOM   10076 C CD2    . LEU B 1 180 ? -22.560 26.653  -8.831  1.00 27.23  ? 180 LEU B CD2    1 
ATOM   10077 H H      . LEU B 1 180 ? -26.419 24.208  -10.334 1.00 29.55  ? 180 LEU B H      1 
ATOM   10078 H HA     . LEU B 1 180 ? -25.430 26.657  -10.978 1.00 30.53  ? 180 LEU B HA     1 
ATOM   10079 H HB2    . LEU B 1 180 ? -25.786 26.037  -8.670  1.00 28.69  ? 180 LEU B HB2    1 
ATOM   10080 H HB3    . LEU B 1 180 ? -24.537 25.085  -8.833  1.00 28.69  ? 180 LEU B HB3    1 
ATOM   10081 H HG     . LEU B 1 180 ? -24.177 27.822  -9.267  1.00 32.60  ? 180 LEU B HG     1 
ATOM   10082 H HD11   . LEU B 1 180 ? -23.712 28.154  -6.996  1.00 30.69  ? 180 LEU B HD11   1 
ATOM   10083 H HD12   . LEU B 1 180 ? -25.237 27.760  -7.204  1.00 30.69  ? 180 LEU B HD12   1 
ATOM   10084 H HD13   . LEU B 1 180 ? -24.199 26.673  -6.689  1.00 30.69  ? 180 LEU B HD13   1 
ATOM   10085 H HD21   . LEU B 1 180 ? -22.010 27.341  -8.425  1.00 32.68  ? 180 LEU B HD21   1 
ATOM   10086 H HD22   . LEU B 1 180 ? -22.420 25.808  -8.377  1.00 32.68  ? 180 LEU B HD22   1 
ATOM   10087 H HD23   . LEU B 1 180 ? -22.337 26.565  -9.771  1.00 32.68  ? 180 LEU B HD23   1 
ATOM   10088 N N      . ALA B 1 181 ? -23.617 25.909  -12.404 1.00 23.44  ? 181 ALA B N      1 
ATOM   10089 C CA     . ALA B 1 181 ? -22.508 25.460  -13.236 1.00 29.26  ? 181 ALA B CA     1 
ATOM   10090 C C      . ALA B 1 181 ? -21.186 26.045  -12.740 1.00 20.42  ? 181 ALA B C      1 
ATOM   10091 O O      . ALA B 1 181 ? -21.108 27.231  -12.436 1.00 23.84  ? 181 ALA B O      1 
ATOM   10092 C CB     . ALA B 1 181 ? -22.750 25.853  -14.689 1.00 25.25  ? 181 ALA B CB     1 
ATOM   10093 H H      . ALA B 1 181 ? -23.956 26.660  -12.651 1.00 28.12  ? 181 ALA B H      1 
ATOM   10094 H HA     . ALA B 1 181 ? -22.447 24.494  -13.195 1.00 35.11  ? 181 ALA B HA     1 
ATOM   10095 H HB1    . ALA B 1 181 ? -22.003 25.547  -15.227 1.00 30.30  ? 181 ALA B HB1    1 
ATOM   10096 H HB2    . ALA B 1 181 ? -23.571 25.438  -14.995 1.00 30.30  ? 181 ALA B HB2    1 
ATOM   10097 H HB3    . ALA B 1 181 ? -22.825 26.818  -14.746 1.00 30.30  ? 181 ALA B HB3    1 
ATOM   10098 N N      . VAL B 1 182 ? -20.157 25.203  -12.658 1.00 23.63  ? 182 VAL B N      1 
ATOM   10099 C CA     . VAL B 1 182 ? -18.795 25.658  -12.367 1.00 21.90  ? 182 VAL B CA     1 
ATOM   10100 C C      . VAL B 1 182 ? -17.808 25.028  -13.370 1.00 25.45  ? 182 VAL B C      1 
ATOM   10101 O O      . VAL B 1 182 ? -17.799 23.807  -13.532 1.00 24.98  ? 182 VAL B O      1 
ATOM   10102 C CB     . VAL B 1 182 ? -18.360 25.293  -10.929 1.00 24.37  ? 182 VAL B CB     1 
ATOM   10103 C CG1    . VAL B 1 182 ? -19.067 26.182  -9.898  1.00 24.87  ? 182 VAL B CG1    1 
ATOM   10104 C CG2    . VAL B 1 182 ? -18.638 23.834  -10.626 1.00 24.00  ? 182 VAL B CG2    1 
ATOM   10105 H H      . VAL B 1 182 ? -20.221 24.353  -12.769 1.00 28.35  ? 182 VAL B H      1 
ATOM   10106 H HA     . VAL B 1 182 ? -18.767 26.620  -12.439 1.00 26.28  ? 182 VAL B HA     1 
ATOM   10107 H HB     . VAL B 1 182 ? -17.405 25.439  -10.843 1.00 29.24  ? 182 VAL B HB     1 
ATOM   10108 H HG11   . VAL B 1 182 ? -18.757 25.942  -9.011  1.00 29.85  ? 182 VAL B HG11   1 
ATOM   10109 H HG12   . VAL B 1 182 ? -18.853 27.109  -10.085 1.00 29.85  ? 182 VAL B HG12   1 
ATOM   10110 H HG13   . VAL B 1 182 ? -20.025 26.042  -9.965  1.00 29.85  ? 182 VAL B HG13   1 
ATOM   10111 H HG21   . VAL B 1 182 ? -18.474 23.676  -9.683  1.00 28.80  ? 182 VAL B HG21   1 
ATOM   10112 H HG22   . VAL B 1 182 ? -19.563 23.631  -10.834 1.00 28.80  ? 182 VAL B HG22   1 
ATOM   10113 H HG23   . VAL B 1 182 ? -18.048 23.278  -11.157 1.00 28.80  ? 182 VAL B HG23   1 
ATOM   10114 N N      . THR B 1 183 ? -17.010 25.815  -14.088 1.00 25.02  ? 183 THR B N      1 
ATOM   10115 C CA     . THR B 1 183 ? -17.158 27.254  -14.280 1.00 22.62  ? 183 THR B CA     1 
ATOM   10116 C C      . THR B 1 183 ? -18.334 27.519  -15.216 1.00 25.46  ? 183 THR B C      1 
ATOM   10117 O O      . THR B 1 183 ? -19.020 26.588  -15.622 1.00 28.32  ? 183 THR B O      1 
ATOM   10118 C CB     . THR B 1 183 ? -15.892 27.848  -14.908 1.00 23.74  ? 183 THR B CB     1 
ATOM   10119 O OG1    . THR B 1 183 ? -15.597 27.121  -16.111 1.00 20.94  ? 183 THR B OG1    1 
ATOM   10120 C CG2    . THR B 1 183 ? -14.717 27.739  -13.967 1.00 19.85  ? 183 THR B CG2    1 
ATOM   10121 H H      . THR B 1 183 ? -16.322 25.510  -14.503 1.00 30.03  ? 183 THR B H      1 
ATOM   10122 H HA     . THR B 1 183 ? -17.312 27.701  -13.435 1.00 27.15  ? 183 THR B HA     1 
ATOM   10123 H HB     . THR B 1 183 ? -16.032 28.784  -15.119 1.00 28.48  ? 183 THR B HB     1 
ATOM   10124 H HG1    . THR B 1 183 ? -14.910 27.437  -16.476 1.00 25.13  ? 183 THR B HG1    1 
ATOM   10125 H HG21   . THR B 1 183 ? -13.929 28.132  -14.374 1.00 23.82  ? 183 THR B HG21   1 
ATOM   10126 H HG22   . THR B 1 183 ? -14.911 28.206  -13.139 1.00 23.82  ? 183 THR B HG22   1 
ATOM   10127 H HG23   . THR B 1 183 ? -14.537 26.807  -13.768 1.00 23.82  ? 183 THR B HG23   1 
ATOM   10128 N N      . VAL B 1 184 ? -18.529 28.781  -15.597 1.00 22.87  ? 184 VAL B N      1 
ATOM   10129 C CA     . VAL B 1 184 ? -19.619 29.164  -16.493 1.00 23.78  ? 184 VAL B CA     1 
ATOM   10130 C C      . VAL B 1 184 ? -19.107 29.354  -17.913 1.00 27.56  ? 184 VAL B C      1 
ATOM   10131 O O      . VAL B 1 184 ? -18.389 30.313  -18.214 1.00 25.01  ? 184 VAL B O      1 
ATOM   10132 C CB     . VAL B 1 184 ? -20.316 30.465  -16.023 1.00 22.34  ? 184 VAL B CB     1 
ATOM   10133 C CG1    . VAL B 1 184 ? -21.435 30.858  -16.993 1.00 25.83  ? 184 VAL B CG1    1 
ATOM   10134 C CG2    . VAL B 1 184 ? -20.881 30.263  -14.641 1.00 23.80  ? 184 VAL B CG2    1 
ATOM   10135 H H      . VAL B 1 184 ? -18.039 29.441  -15.347 1.00 27.44  ? 184 VAL B H      1 
ATOM   10136 H HA     . VAL B 1 184 ? -20.288 28.463  -16.508 1.00 28.54  ? 184 VAL B HA     1 
ATOM   10137 H HB     . VAL B 1 184 ? -19.669 31.187  -15.990 1.00 26.80  ? 184 VAL B HB     1 
ATOM   10138 H HG11   . VAL B 1 184 ? -22.000 31.522  -16.568 1.00 30.99  ? 184 VAL B HG11   1 
ATOM   10139 H HG12   . VAL B 1 184 ? -21.043 31.227  -17.800 1.00 30.99  ? 184 VAL B HG12   1 
ATOM   10140 H HG13   . VAL B 1 184 ? -21.958 30.070  -17.207 1.00 30.99  ? 184 VAL B HG13   1 
ATOM   10141 H HG21   . VAL B 1 184 ? -21.356 31.065  -14.374 1.00 28.56  ? 184 VAL B HG21   1 
ATOM   10142 H HG22   . VAL B 1 184 ? -21.489 29.508  -14.657 1.00 28.56  ? 184 VAL B HG22   1 
ATOM   10143 H HG23   . VAL B 1 184 ? -20.153 30.089  -14.024 1.00 28.56  ? 184 VAL B HG23   1 
ATOM   10144 N N      . ASN B 1 185 ? -19.522 28.445  -18.785 1.00 28.07  ? 185 ASN B N      1 
ATOM   10145 C CA     . ASN B 1 185 ? -19.008 28.365  -20.137 1.00 27.99  ? 185 ASN B CA     1 
ATOM   10146 C C      . ASN B 1 185 ? -19.370 29.572  -21.000 1.00 32.38  ? 185 ASN B C      1 
ATOM   10147 O O      . ASN B 1 185 ? -18.509 30.175  -21.648 1.00 28.50  ? 185 ASN B O      1 
ATOM   10148 C CB     . ASN B 1 185 ? -19.527 27.084  -20.782 1.00 34.81  ? 185 ASN B CB     1 
ATOM   10149 C CG     . ASN B 1 185 ? -18.998 26.889  -22.171 1.00 43.70  ? 185 ASN B CG     1 
ATOM   10150 O OD1    . ASN B 1 185 ? -19.754 26.840  -23.142 1.00 56.07  ? 185 ASN B OD1    1 
ATOM   10151 N ND2    . ASN B 1 185 ? -17.682 26.803  -22.284 1.00 41.43  ? 185 ASN B ND2    1 
ATOM   10152 H H      . ASN B 1 185 ? -20.117 27.849  -18.609 1.00 33.68  ? 185 ASN B H      1 
ATOM   10153 H HA     . ASN B 1 185 ? -18.040 28.308  -20.100 1.00 33.59  ? 185 ASN B HA     1 
ATOM   10154 H HB2    . ASN B 1 185 ? -19.251 26.324  -20.245 1.00 41.77  ? 185 ASN B HB2    1 
ATOM   10155 H HB3    . ASN B 1 185 ? -20.495 27.123  -20.831 1.00 41.77  ? 185 ASN B HB3    1 
ATOM   10156 H HD21   . ASN B 1 185 ? -17.309 26.931  -23.047 1.00 49.71  ? 185 ASN B HD21   1 
ATOM   10157 H HD22   . ASN B 1 185 ? -17.201 26.627  -21.593 1.00 49.71  ? 185 ASN B HD22   1 
ATOM   10158 N N      . LEU B 1 186 ? -20.649 29.928  -20.994 1.00 30.11  ? 186 LEU B N      1 
ATOM   10159 C CA     . LEU B 1 186 ? -21.174 30.939  -21.904 1.00 30.34  ? 186 LEU B CA     1 
ATOM   10160 C C      . LEU B 1 186 ? -20.619 32.333  -21.621 1.00 33.08  ? 186 LEU B C      1 
ATOM   10161 O O      . LEU B 1 186 ? -20.674 33.221  -22.476 1.00 34.30  ? 186 LEU B O      1 
ATOM   10162 C CB     . LEU B 1 186 ? -22.697 30.954  -21.815 1.00 34.38  ? 186 LEU B CB     1 
ATOM   10163 C CG     . LEU B 1 186 ? -23.482 31.577  -22.965 1.00 43.70  ? 186 LEU B CG     1 
ATOM   10164 C CD1    . LEU B 1 186 ? -23.114 30.934  -24.294 1.00 43.55  ? 186 LEU B CD1    1 
ATOM   10165 C CD2    . LEU B 1 186 ? -24.970 31.420  -22.692 1.00 48.24  ? 186 LEU B CD2    1 
ATOM   10166 H H      . LEU B 1 186 ? -21.240 29.595  -20.466 1.00 36.13  ? 186 LEU B H      1 
ATOM   10167 H HA     . LEU B 1 186 ? -20.923 30.699  -22.809 1.00 36.41  ? 186 LEU B HA     1 
ATOM   10168 H HB2    . LEU B 1 186 ? -22.999 30.036  -21.735 1.00 41.26  ? 186 LEU B HB2    1 
ATOM   10169 H HB3    . LEU B 1 186 ? -22.943 31.438  -21.011 1.00 41.26  ? 186 LEU B HB3    1 
ATOM   10170 H HG     . LEU B 1 186 ? -23.279 32.524  -23.017 1.00 52.45  ? 186 LEU B HG     1 
ATOM   10171 H HD11   . LEU B 1 186 ? -23.763 31.202  -24.963 1.00 52.26  ? 186 LEU B HD11   1 
ATOM   10172 H HD12   . LEU B 1 186 ? -22.229 31.231  -24.556 1.00 52.26  ? 186 LEU B HD12   1 
ATOM   10173 H HD13   . LEU B 1 186 ? -23.125 29.969  -24.192 1.00 52.26  ? 186 LEU B HD13   1 
ATOM   10174 H HD21   . LEU B 1 186 ? -25.468 31.821  -23.421 1.00 57.89  ? 186 LEU B HD21   1 
ATOM   10175 H HD22   . LEU B 1 186 ? -25.181 30.475  -22.626 1.00 57.89  ? 186 LEU B HD22   1 
ATOM   10176 H HD23   . LEU B 1 186 ? -25.186 31.866  -21.858 1.00 57.89  ? 186 LEU B HD23   1 
ATOM   10177 N N      . ALA B 1 187 ? -20.088 32.517  -20.415 1.00 28.28  ? 187 ALA B N      1 
ATOM   10178 C CA     . ALA B 1 187 ? -19.470 33.776  -20.019 1.00 29.17  ? 187 ALA B CA     1 
ATOM   10179 C C      . ALA B 1 187 ? -17.972 33.778  -20.325 1.00 27.19  ? 187 ALA B C      1 
ATOM   10180 O O      . ALA B 1 187 ? -17.274 34.744  -20.025 1.00 25.75  ? 187 ALA B O      1 
ATOM   10181 C CB     . ALA B 1 187 ? -19.701 34.027  -18.538 1.00 29.39  ? 187 ALA B CB     1 
ATOM   10182 H H      . ALA B 1 187 ? -20.074 31.918  -19.798 1.00 33.94  ? 187 ALA B H      1 
ATOM   10183 H HA     . ALA B 1 187 ? -19.879 34.505  -20.511 1.00 35.01  ? 187 ALA B HA     1 
ATOM   10184 H HB1    . ALA B 1 187 ? -19.286 34.869  -18.292 1.00 35.27  ? 187 ALA B HB1    1 
ATOM   10185 H HB2    . ALA B 1 187 ? -20.656 34.067  -18.370 1.00 35.27  ? 187 ALA B HB2    1 
ATOM   10186 H HB3    . ALA B 1 187 ? -19.305 33.302  -18.030 1.00 35.27  ? 187 ALA B HB3    1 
ATOM   10187 N N      . GLY B 1 188 ? -17.483 32.687  -20.910 1.00 27.05  ? 188 GLY B N      1 
ATOM   10188 C CA     . GLY B 1 188 ? -16.072 32.544  -21.230 1.00 25.96  ? 188 GLY B CA     1 
ATOM   10189 C C      . GLY B 1 188 ? -15.288 31.667  -20.261 1.00 28.72  ? 188 GLY B C      1 
ATOM   10190 O O      . GLY B 1 188 ? -14.062 31.721  -20.259 1.00 26.60  ? 188 GLY B O      1 
ATOM   10191 H H      . GLY B 1 188 ? -17.955 32.005  -21.136 1.00 32.45  ? 188 GLY B H      1 
ATOM   10192 H HA2    . GLY B 1 188 ? -15.997 32.154  -22.112 1.00 31.16  ? 188 GLY B HA2    1 
ATOM   10193 H HA3    . GLY B 1 188 ? -15.651 33.417  -21.254 1.00 31.16  ? 188 GLY B HA3    1 
ATOM   10194 N N      . GLY B 1 189 ? -15.981 30.871  -19.444 1.00 21.87  ? 189 GLY B N      1 
ATOM   10195 C CA     . GLY B 1 189 ? -15.324 30.015  -18.461 1.00 24.50  ? 189 GLY B CA     1 
ATOM   10196 C C      . GLY B 1 189 ? -15.073 30.733  -17.143 1.00 25.13  ? 189 GLY B C      1 
ATOM   10197 O O      . GLY B 1 189 ? -13.963 30.696  -16.585 1.00 19.17  ? 189 GLY B O      1 
ATOM   10198 H H      . GLY B 1 189 ? -16.839 30.810  -19.441 1.00 26.24  ? 189 GLY B H      1 
ATOM   10199 H HA2    . GLY B 1 189 ? -15.881 29.241  -18.286 1.00 29.40  ? 189 GLY B HA2    1 
ATOM   10200 H HA3    . GLY B 1 189 ? -14.474 29.707  -18.811 1.00 29.40  ? 189 GLY B HA3    1 
ATOM   10201 N N      . GLN B 1 190 ? -16.116 31.389  -16.641 1.00 20.65  ? 190 GLN B N      1 
ATOM   10202 C CA     . GLN B 1 190 ? -15.992 32.247  -15.461 1.00 21.40  ? 190 GLN B CA     1 
ATOM   10203 C C      . GLN B 1 190 ? -16.333 31.502  -14.174 1.00 18.84  ? 190 GLN B C      1 
ATOM   10204 O O      . GLN B 1 190 ? -17.302 30.736  -14.127 1.00 18.24  ? 190 GLN B O      1 
ATOM   10205 C CB     . GLN B 1 190 ? -16.899 33.463  -15.599 1.00 25.11  ? 190 GLN B CB     1 
ATOM   10206 C CG     . GLN B 1 190 ? -16.695 34.245  -16.886 1.00 23.57  ? 190 GLN B CG     1 
ATOM   10207 C CD     . GLN B 1 190 ? -15.308 34.847  -17.004 1.00 26.17  ? 190 GLN B CD     1 
ATOM   10208 O OE1    . GLN B 1 190 ? -14.631 35.104  -16.005 1.00 20.50  ? 190 GLN B OE1    1 
ATOM   10209 N NE2    . GLN B 1 190 ? -14.881 35.089  -18.237 1.00 25.93  ? 190 GLN B NE2    1 
ATOM   10210 H H      . GLN B 1 190 ? -16.911 31.355  -16.966 1.00 24.78  ? 190 GLN B H      1 
ATOM   10211 H HA     . GLN B 1 190 ? -15.080 32.567  -15.413 1.00 25.68  ? 190 GLN B HA     1 
ATOM   10212 H HB2    . GLN B 1 190 ? -17.822 33.167  -15.577 1.00 30.14  ? 190 GLN B HB2    1 
ATOM   10213 H HB3    . GLN B 1 190 ? -16.730 34.064  -14.857 1.00 30.14  ? 190 GLN B HB3    1 
ATOM   10214 H HG2    . GLN B 1 190 ? -16.829 33.652  -17.642 1.00 28.28  ? 190 GLN B HG2    1 
ATOM   10215 H HG3    . GLN B 1 190 ? -17.338 34.970  -16.918 1.00 28.28  ? 190 GLN B HG3    1 
ATOM   10216 H HE21   . GLN B 1 190 ? -15.384 34.905  -18.910 1.00 31.12  ? 190 GLN B HE21   1 
ATOM   10217 H HE22   . GLN B 1 190 ? -14.102 35.430  -18.363 1.00 31.12  ? 190 GLN B HE22   1 
ATOM   10218 N N      . PRO B 1 191 ? -15.549 31.737  -13.115 1.00 17.73  ? 191 PRO B N      1 
ATOM   10219 C CA     . PRO B 1 191 ? -15.774 30.987  -11.879 1.00 21.55  ? 191 PRO B CA     1 
ATOM   10220 C C      . PRO B 1 191 ? -16.915 31.511  -11.001 1.00 23.07  ? 191 PRO B C      1 
ATOM   10221 O O      . PRO B 1 191 ? -17.451 32.617  -11.205 1.00 21.38  ? 191 PRO B O      1 
ATOM   10222 C CB     . PRO B 1 191 ? -14.439 31.128  -11.155 1.00 20.12  ? 191 PRO B CB     1 
ATOM   10223 C CG     . PRO B 1 191 ? -13.948 32.474  -11.575 1.00 21.39  ? 191 PRO B CG     1 
ATOM   10224 C CD     . PRO B 1 191 ? -14.353 32.593  -13.021 1.00 21.56  ? 191 PRO B CD     1 
ATOM   10225 H HA     . PRO B 1 191 ? -15.930 30.053  -12.083 1.00 25.86  ? 191 PRO B HA     1 
ATOM   10226 H HB2    . PRO B 1 191 ? -14.578 31.093  -10.196 1.00 24.14  ? 191 PRO B HB2    1 
ATOM   10227 H HB3    . PRO B 1 191 ? -13.830 30.431  -11.445 1.00 24.14  ? 191 PRO B HB3    1 
ATOM   10228 H HG2    . PRO B 1 191 ? -14.376 33.161  -11.040 1.00 25.67  ? 191 PRO B HG2    1 
ATOM   10229 H HG3    . PRO B 1 191 ? -12.984 32.516  -11.483 1.00 25.67  ? 191 PRO B HG3    1 
ATOM   10230 H HD2    . PRO B 1 191 ? -14.578 33.512  -13.235 1.00 25.87  ? 191 PRO B HD2    1 
ATOM   10231 H HD3    . PRO B 1 191 ? -13.650 32.255  -13.597 1.00 25.87  ? 191 PRO B HD3    1 
ATOM   10232 N N      . VAL B 1 192 ? -17.264 30.679  -10.022 1.00 21.75  ? 192 VAL B N      1 
ATOM   10233 C CA     . VAL B 1 192 ? -18.284 30.960  -9.015  1.00 20.37  ? 192 VAL B CA     1 
ATOM   10234 C C      . VAL B 1 192 ? -17.612 30.892  -7.649  1.00 20.40  ? 192 VAL B C      1 
ATOM   10235 O O      . VAL B 1 192 ? -16.827 29.978  -7.389  1.00 20.19  ? 192 VAL B O      1 
ATOM   10236 C CB     . VAL B 1 192 ? -19.448 29.943  -9.085  1.00 18.35  ? 192 VAL B CB     1 
ATOM   10237 C CG1    . VAL B 1 192 ? -20.430 30.124  -7.926  1.00 21.10  ? 192 VAL B CG1    1 
ATOM   10238 C CG2    . VAL B 1 192 ? -20.160 30.032  -10.421 1.00 22.30  ? 192 VAL B CG2    1 
ATOM   10239 H H      . VAL B 1 192 ? -16.903 29.905  -9.918  1.00 26.10  ? 192 VAL B H      1 
ATOM   10240 H HA     . VAL B 1 192 ? -18.640 31.851  -9.145  1.00 24.44  ? 192 VAL B HA     1 
ATOM   10241 H HB     . VAL B 1 192 ? -19.077 29.050  -9.012  1.00 22.02  ? 192 VAL B HB     1 
ATOM   10242 H HG11   . VAL B 1 192 ? -21.238 29.623  -8.118  1.00 25.32  ? 192 VAL B HG11   1 
ATOM   10243 H HG12   . VAL B 1 192 ? -20.024 29.793  -7.110  1.00 25.32  ? 192 VAL B HG12   1 
ATOM   10244 H HG13   . VAL B 1 192 ? -20.640 31.067  -7.835  1.00 25.32  ? 192 VAL B HG13   1 
ATOM   10245 H HG21   . VAL B 1 192 ? -20.879 29.381  -10.439 1.00 26.77  ? 192 VAL B HG21   1 
ATOM   10246 H HG22   . VAL B 1 192 ? -20.520 30.926  -10.526 1.00 26.77  ? 192 VAL B HG22   1 
ATOM   10247 H HG23   . VAL B 1 192 ? -19.526 29.844  -11.130 1.00 26.77  ? 192 VAL B HG23   1 
ATOM   10248 N N      . SER B 1 193 ? -17.899 31.857  -6.778  1.00 17.89  ? 193 SER B N      1 
ATOM   10249 C CA     . SER B 1 193 ? -17.248 31.899  -5.466  1.00 18.73  ? 193 SER B CA     1 
ATOM   10250 C C      . SER B 1 193 ? -17.894 30.934  -4.478  1.00 18.36  ? 193 SER B C      1 
ATOM   10251 O O      . SER B 1 193 ? -19.075 30.591  -4.600  1.00 21.00  ? 193 SER B O      1 
ATOM   10252 C CB     . SER B 1 193 ? -17.286 33.314  -4.884  1.00 23.09  ? 193 SER B CB     1 
ATOM   10253 O OG     . SER B 1 193 ? -18.626 33.724  -4.675  1.00 23.18  ? 193 SER B OG     1 
ATOM   10254 H H      . SER B 1 193 ? -18.460 32.493  -6.918  1.00 21.47  ? 193 SER B H      1 
ATOM   10255 H HA     . SER B 1 193 ? -16.317 31.645  -5.566  1.00 22.48  ? 193 SER B HA     1 
ATOM   10256 H HB2    . SER B 1 193 ? -16.816 33.321  -4.036  1.00 27.71  ? 193 SER B HB2    1 
ATOM   10257 H HB3    . SER B 1 193 ? -16.861 33.925  -5.506  1.00 27.71  ? 193 SER B HB3    1 
ATOM   10258 H HG     . SER B 1 193 ? -18.642 34.488  -4.327  1.00 27.82  ? 193 SER B HG     1 
ATOM   10259 N N      . MET B 1 194 ? -17.125 30.538  -3.469  1.00 19.81  ? 194 MET B N      1 
ATOM   10260 C CA     . MET B 1 194 ? -17.668 29.734  -2.383  1.00 19.96  ? 194 MET B CA     1 
ATOM   10261 C C      . MET B 1 194 ? -18.776 30.513  -1.679  1.00 19.57  ? 194 MET B C      1 
ATOM   10262 O O      . MET B 1 194 ? -19.792 29.943  -1.296  1.00 20.52  ? 194 MET B O      1 
ATOM   10263 C CB     . MET B 1 194 ? -16.583 29.350  -1.383  1.00 18.32  ? 194 MET B CB     1 
ATOM   10264 C CG     . MET B 1 194 ? -16.999 28.226  -0.436  1.00 21.17  ? 194 MET B CG     1 
ATOM   10265 S SD     . MET B 1 194 ? -16.853 26.599  -1.234  1.00 21.91  ? 194 MET B SD     1 
ATOM   10266 C CE     . MET B 1 194 ? -15.071 26.438  -1.256  1.00 20.34  ? 194 MET B CE     1 
ATOM   10267 H H      . MET B 1 194 ? -16.288 30.721  -3.391  1.00 23.77  ? 194 MET B H      1 
ATOM   10268 H HA     . MET B 1 194 ? -18.040 28.917  -2.750  1.00 23.95  ? 194 MET B HA     1 
ATOM   10269 H HB2    . MET B 1 194 ? -15.798 29.057  -1.870  1.00 21.98  ? 194 MET B HB2    1 
ATOM   10270 H HB3    . MET B 1 194 ? -16.365 30.127  -0.844  1.00 21.98  ? 194 MET B HB3    1 
ATOM   10271 H HG2    . MET B 1 194 ? -16.423 28.235  0.344   1.00 25.41  ? 194 MET B HG2    1 
ATOM   10272 H HG3    . MET B 1 194 ? -17.924 28.353  -0.172  1.00 25.41  ? 194 MET B HG3    1 
ATOM   10273 H HE1    . MET B 1 194 ? -14.840 25.544  -1.552  1.00 24.41  ? 194 MET B HE1    1 
ATOM   10274 H HE2    . MET B 1 194 ? -14.700 27.094  -1.867  1.00 24.41  ? 194 MET B HE2    1 
ATOM   10275 H HE3    . MET B 1 194 ? -14.730 26.588  -0.360  1.00 24.41  ? 194 MET B HE3    1 
ATOM   10276 N N      . ALA B 1 195 ? -18.576 31.819  -1.535  1.00 21.59  ? 195 ALA B N      1 
ATOM   10277 C CA     . ALA B 1 195 ? -19.560 32.674  -0.882  1.00 19.36  ? 195 ALA B CA     1 
ATOM   10278 C C      . ALA B 1 195 ? -20.888 32.577  -1.612  1.00 22.43  ? 195 ALA B C      1 
ATOM   10279 O O      . ALA B 1 195 ? -21.944 32.464  -0.990  1.00 24.03  ? 195 ALA B O      1 
ATOM   10280 C CB     . ALA B 1 195 ? -19.071 34.115  -0.829  1.00 23.41  ? 195 ALA B CB     1 
ATOM   10281 H H      . ALA B 1 195 ? -17.875 32.236  -1.808  1.00 25.90  ? 195 ALA B H      1 
ATOM   10282 H HA     . ALA B 1 195 ? -19.693 32.367  0.028   1.00 23.23  ? 195 ALA B HA     1 
ATOM   10283 H HB1    . ALA B 1 195 ? -19.743 34.660  -0.391  1.00 28.09  ? 195 ALA B HB1    1 
ATOM   10284 H HB2    . ALA B 1 195 ? -18.240 34.148  -0.329  1.00 28.09  ? 195 ALA B HB2    1 
ATOM   10285 H HB3    . ALA B 1 195 ? -18.926 34.432  -1.734  1.00 28.09  ? 195 ALA B HB3    1 
ATOM   10286 N N      . ASN B 1 196 ? -20.833 32.577  -2.939  1.00 22.99  ? 196 ASN B N      1 
ATOM   10287 C CA     . ASN B 1 196 ? -22.046 32.465  -3.741  1.00 21.64  ? 196 ASN B CA     1 
ATOM   10288 C C      . ASN B 1 196 ? -22.726 31.103  -3.554  1.00 23.09  ? 196 ASN B C      1 
ATOM   10289 O O      . ASN B 1 196 ? -23.943 31.022  -3.396  1.00 25.06  ? 196 ASN B O      1 
ATOM   10290 C CB     . ASN B 1 196 ? -21.715 32.707  -5.215  1.00 23.50  ? 196 ASN B CB     1 
ATOM   10291 C CG     . ASN B 1 196 ? -22.952 32.916  -6.072  1.00 27.26  ? 196 ASN B CG     1 
ATOM   10292 O OD1    . ASN B 1 196 ? -23.173 32.187  -7.034  1.00 24.38  ? 196 ASN B OD1    1 
ATOM   10293 N ND2    . ASN B 1 196 ? -23.760 33.919  -5.730  1.00 29.89  ? 196 ASN B ND2    1 
ATOM   10294 H H      . ASN B 1 196 ? -20.109 32.640  -3.398  1.00 27.59  ? 196 ASN B H      1 
ATOM   10295 H HA     . ASN B 1 196 ? -22.672 33.150  -3.459  1.00 25.96  ? 196 ASN B HA     1 
ATOM   10296 H HB2    . ASN B 1 196 ? -21.163 33.501  -5.288  1.00 28.20  ? 196 ASN B HB2    1 
ATOM   10297 H HB3    . ASN B 1 196 ? -21.237 31.938  -5.562  1.00 28.20  ? 196 ASN B HB3    1 
ATOM   10298 H HD21   . ASN B 1 196 ? -24.472 34.072  -6.187  1.00 35.87  ? 196 ASN B HD21   1 
ATOM   10299 H HD22   . ASN B 1 196 ? -23.569 34.413  -5.052  1.00 35.87  ? 196 ASN B HD22   1 
ATOM   10300 N N      . MET B 1 197 ? -21.945 30.029  -3.563  1.00 22.96  ? 197 MET B N      1 
ATOM   10301 C CA     . MET B 1 197 ? -22.501 28.693  -3.349  1.00 20.51  ? 197 MET B CA     1 
ATOM   10302 C C      . MET B 1 197 ? -23.198 28.573  -1.988  1.00 23.39  ? 197 MET B C      1 
ATOM   10303 O O      . MET B 1 197 ? -24.260 27.962  -1.883  1.00 21.68  ? 197 MET B O      1 
ATOM   10304 C CB     . MET B 1 197 ? -21.398 27.646  -3.469  1.00 22.65  ? 197 MET B CB     1 
ATOM   10305 C CG     . MET B 1 197 ? -20.826 27.554  -4.861  1.00 25.33  ? 197 MET B CG     1 
ATOM   10306 S SD     . MET B 1 197 ? -19.425 26.431  -4.925  1.00 27.53  ? 197 MET B SD     1 
ATOM   10307 C CE     . MET B 1 197 ? -18.498 27.153  -6.264  1.00 24.35  ? 197 MET B CE     1 
ATOM   10308 H H      . MET B 1 197 ? -21.095 30.043  -3.690  1.00 27.55  ? 197 MET B H      1 
ATOM   10309 H HA     . MET B 1 197 ? -23.152 28.514  -4.046  1.00 24.61  ? 197 MET B HA     1 
ATOM   10310 H HB2    . MET B 1 197 ? -20.676 27.877  -2.863  1.00 27.18  ? 197 MET B HB2    1 
ATOM   10311 H HB3    . MET B 1 197 ? -21.761 26.777  -3.236  1.00 27.18  ? 197 MET B HB3    1 
ATOM   10312 H HG2    . MET B 1 197 ? -21.508 27.223  -5.466  1.00 30.39  ? 197 MET B HG2    1 
ATOM   10313 H HG3    . MET B 1 197 ? -20.525 28.432  -5.142  1.00 30.39  ? 197 MET B HG3    1 
ATOM   10314 H HE1    . MET B 1 197 ? -19.026 27.103  -7.076  1.00 29.22  ? 197 MET B HE1    1 
ATOM   10315 H HE2    . MET B 1 197 ? -18.307 28.080  -6.051  1.00 29.22  ? 197 MET B HE2    1 
ATOM   10316 H HE3    . MET B 1 197 ? -17.670 26.662  -6.376  1.00 29.22  ? 197 MET B HE3    1 
ATOM   10317 N N      . ARG B 1 198 ? -22.585 29.153  -0.958  1.00 21.85  ? 198 ARG B N      1 
ATOM   10318 C CA     . ARG B 1 198 ? -23.177 29.216  0.381   1.00 25.88  ? 198 ARG B CA     1 
ATOM   10319 C C      . ARG B 1 198 ? -24.507 29.962  0.406   1.00 24.79  ? 198 ARG B C      1 
ATOM   10320 O O      . ARG B 1 198 ? -25.473 29.509  1.025   1.00 24.54  ? 198 ARG B O      1 
ATOM   10321 C CB     . ARG B 1 198 ? -22.226 29.899  1.358   1.00 24.96  ? 198 ARG B CB     1 
ATOM   10322 C CG     . ARG B 1 198 ? -20.998 29.108  1.677   1.00 22.60  ? 198 ARG B CG     1 
ATOM   10323 C CD     . ARG B 1 198 ? -20.116 29.848  2.650   1.00 29.06  ? 198 ARG B CD     1 
ATOM   10324 N NE     . ARG B 1 198 ? -18.919 29.087  2.975   1.00 28.64  ? 198 ARG B NE     1 
ATOM   10325 C CZ     . ARG B 1 198 ? -17.817 29.604  3.503   1.00 26.18  ? 198 ARG B CZ     1 
ATOM   10326 N NH1    . ARG B 1 198 ? -17.743 30.901  3.775   1.00 32.15  ? 198 ARG B NH1    1 
ATOM   10327 N NH2    . ARG B 1 198 ? -16.783 28.818  3.753   1.00 27.23  ? 198 ARG B NH2    1 
ATOM   10328 H H      . ARG B 1 198 ? -21.811 29.524  -1.009  1.00 26.21  ? 198 ARG B H      1 
ATOM   10329 H HA     . ARG B 1 198 ? -23.335 28.313  0.698   1.00 31.06  ? 198 ARG B HA     1 
ATOM   10330 H HB2    . ARG B 1 198 ? -21.941 30.744  0.976   1.00 29.95  ? 198 ARG B HB2    1 
ATOM   10331 H HB3    . ARG B 1 198 ? -22.698 30.059  2.190   1.00 29.95  ? 198 ARG B HB3    1 
ATOM   10332 H HG2    . ARG B 1 198 ? -21.263 28.272  2.087   1.00 27.12  ? 198 ARG B HG2    1 
ATOM   10333 H HG3    . ARG B 1 198 ? -20.494 28.942  0.866   1.00 27.12  ? 198 ARG B HG3    1 
ATOM   10334 H HD2    . ARG B 1 198 ? -19.844 30.690  2.253   1.00 34.87  ? 198 ARG B HD2    1 
ATOM   10335 H HD3    . ARG B 1 198 ? -20.608 30.007  3.471   1.00 34.87  ? 198 ARG B HD3    1 
ATOM   10336 H HE     . ARG B 1 198 ? -18.907 28.254  2.764   1.00 34.36  ? 198 ARG B HE     1 
ATOM   10337 H HH11   . ARG B 1 198 ? -18.411 31.417  3.613   1.00 38.57  ? 198 ARG B HH11   1 
ATOM   10338 H HH12   . ARG B 1 198 ? -17.024 31.226  4.117   1.00 38.57  ? 198 ARG B HH12   1 
ATOM   10339 H HH21   . ARG B 1 198 ? -16.829 27.978  3.577   1.00 32.68  ? 198 ARG B HH21   1 
ATOM   10340 H HH22   . ARG B 1 198 ? -16.067 29.147  4.095   1.00 32.68  ? 198 ARG B HH22   1 
ATOM   10341 N N      . GLU B 1 199 ? -24.544 31.116  -0.253  1.00 27.97  ? 199 GLU B N      1 
ATOM   10342 C CA     . GLU B 1 199 ? -25.742 31.951  -0.255  1.00 26.62  ? 199 GLU B CA     1 
ATOM   10343 C C      . GLU B 1 199 ? -26.885 31.285  -1.006  1.00 30.84  ? 199 GLU B C      1 
ATOM   10344 O O      . GLU B 1 199 ? -28.033 31.344  -0.570  1.00 29.25  ? 199 GLU B O      1 
ATOM   10345 C CB     . GLU B 1 199 ? -25.448 33.322  -0.868  1.00 33.33  ? 199 GLU B CB     1 
ATOM   10346 C CG     . GLU B 1 199 ? -24.591 34.216  0.015   1.00 40.53  ? 199 GLU B CG     1 
ATOM   10347 C CD     . GLU B 1 199 ? -24.716 35.688  -0.335  1.00 59.63  ? 199 GLU B CD     1 
ATOM   10348 O OE1    . GLU B 1 199 ? -24.954 36.008  -1.519  1.00 50.20  ? 199 GLU B OE1    1 
ATOM   10349 O OE2    . GLU B 1 199 ? -24.577 36.528  0.580   1.00 79.55  ? 199 GLU B OE2    1 
ATOM   10350 H H      . GLU B 1 199 ? -23.889 31.439  -0.707  1.00 33.56  ? 199 GLU B H      1 
ATOM   10351 H HA     . GLU B 1 199 ? -26.029 32.090  0.661   1.00 31.94  ? 199 GLU B HA     1 
ATOM   10352 H HB2    . GLU B 1 199 ? -24.978 33.195  -1.707  1.00 40.00  ? 199 GLU B HB2    1 
ATOM   10353 H HB3    . GLU B 1 199 ? -26.288 33.780  -1.027  1.00 40.00  ? 199 GLU B HB3    1 
ATOM   10354 H HG2    . GLU B 1 199 ? -24.859 34.101  0.940   1.00 48.63  ? 199 GLU B HG2    1 
ATOM   10355 H HG3    . GLU B 1 199 ? -23.663 33.967  -0.097  1.00 48.63  ? 199 GLU B HG3    1 
ATOM   10356 N N      . VAL B 1 200 ? -26.577 30.662  -2.141  1.00 24.22  ? 200 VAL B N      1 
ATOM   10357 C CA     . VAL B 1 200 ? -27.573 29.885  -2.866  1.00 26.64  ? 200 VAL B CA     1 
ATOM   10358 C C      . VAL B 1 200 ? -28.079 28.725  -1.997  1.00 25.84  ? 200 VAL B C      1 
ATOM   10359 O O      . VAL B 1 200 ? -29.276 28.443  -1.971  1.00 25.13  ? 200 VAL B O      1 
ATOM   10360 C CB     . VAL B 1 200 ? -26.999 29.346  -4.197  1.00 23.03  ? 200 VAL B CB     1 
ATOM   10361 C CG1    . VAL B 1 200 ? -27.974 28.390  -4.872  1.00 26.44  ? 200 VAL B CG1    1 
ATOM   10362 C CG2    . VAL B 1 200 ? -26.650 30.499  -5.133  1.00 23.51  ? 200 VAL B CG2    1 
ATOM   10363 H H      . VAL B 1 200 ? -25.800 30.674  -2.510  1.00 29.06  ? 200 VAL B H      1 
ATOM   10364 H HA     . VAL B 1 200 ? -28.329 30.456  -3.075  1.00 31.97  ? 200 VAL B HA     1 
ATOM   10365 H HB     . VAL B 1 200 ? -26.183 28.856  -4.011  1.00 27.63  ? 200 VAL B HB     1 
ATOM   10366 H HG11   . VAL B 1 200 ? -27.711 28.277  -5.799  1.00 31.73  ? 200 VAL B HG11   1 
ATOM   10367 H HG12   . VAL B 1 200 ? -27.949 27.534  -4.416  1.00 31.73  ? 200 VAL B HG12   1 
ATOM   10368 H HG13   . VAL B 1 200 ? -28.867 28.766  -4.827  1.00 31.73  ? 200 VAL B HG13   1 
ATOM   10369 H HG21   . VAL B 1 200 ? -26.133 30.154  -5.878  1.00 28.21  ? 200 VAL B HG21   1 
ATOM   10370 H HG22   . VAL B 1 200 ? -27.471 30.900  -5.458  1.00 28.21  ? 200 VAL B HG22   1 
ATOM   10371 H HG23   . VAL B 1 200 ? -26.130 31.158  -4.647  1.00 28.21  ? 200 VAL B HG23   1 
ATOM   10372 N N      . ARG B 1 201 ? -27.173 28.055  -1.287  1.00 29.28  ? 201 ARG B N      1 
ATOM   10373 C CA     . ARG B 1 201 ? -27.550 26.921  -0.443  1.00 27.61  ? 201 ARG B CA     1 
ATOM   10374 C C      . ARG B 1 201 ? -28.488 27.371  0.673   1.00 30.74  ? 201 ARG B C      1 
ATOM   10375 O O      . ARG B 1 201 ? -29.517 26.748  0.929   1.00 29.88  ? 201 ARG B O      1 
ATOM   10376 C CB     . ARG B 1 201 ? -26.308 26.253  0.160   1.00 29.12  ? 201 ARG B CB     1 
ATOM   10377 C CG     . ARG B 1 201 ? -26.589 25.144  1.189   1.00 30.16  ? 201 ARG B CG     1 
ATOM   10378 C CD     . ARG B 1 201 ? -26.954 23.820  0.537   1.00 36.69  ? 201 ARG B CD     1 
ATOM   10379 N NE     . ARG B 1 201 ? -28.294 23.811  -0.043  1.00 38.94  ? 201 ARG B NE     1 
ATOM   10380 C CZ     . ARG B 1 201 ? -28.849 22.756  -0.636  1.00 41.32  ? 201 ARG B CZ     1 
ATOM   10381 N NH1    . ARG B 1 201 ? -28.181 21.620  -0.741  1.00 48.75  ? 201 ARG B NH1    1 
ATOM   10382 N NH2    . ARG B 1 201 ? -30.078 22.833  -1.128  1.00 45.29  ? 201 ARG B NH2    1 
ATOM   10383 H H      . ARG B 1 201 ? -26.333 28.237  -1.276  1.00 35.14  ? 201 ARG B H      1 
ATOM   10384 H HA     . ARG B 1 201 ? -28.016 26.264  -0.983  1.00 33.13  ? 201 ARG B HA     1 
ATOM   10385 H HB2    . ARG B 1 201 ? -25.792 25.859  -0.560  1.00 34.94  ? 201 ARG B HB2    1 
ATOM   10386 H HB3    . ARG B 1 201 ? -25.778 26.934  0.603   1.00 34.94  ? 201 ARG B HB3    1 
ATOM   10387 H HG2    . ARG B 1 201 ? -25.787 25.000  1.715   1.00 36.19  ? 201 ARG B HG2    1 
ATOM   10388 H HG3    . ARG B 1 201 ? -27.318 25.402  1.773   1.00 36.19  ? 201 ARG B HG3    1 
ATOM   10389 H HD2    . ARG B 1 201 ? -26.319 23.632  -0.167  1.00 44.03  ? 201 ARG B HD2    1 
ATOM   10390 H HD3    . ARG B 1 201 ? -26.917 23.121  1.208   1.00 44.03  ? 201 ARG B HD3    1 
ATOM   10391 H HE     . ARG B 1 201 ? -28.781 24.512  0.064   1.00 46.72  ? 201 ARG B HE     1 
ATOM   10392 H HH11   . ARG B 1 201 ? -27.384 21.556  -0.425  1.00 58.50  ? 201 ARG B HH11   1 
ATOM   10393 H HH12   . ARG B 1 201 ? -28.545 20.943  -1.127  1.00 58.50  ? 201 ARG B HH12   1 
ATOM   10394 H HH21   . ARG B 1 201 ? -30.520 23.568  -1.067  1.00 54.35  ? 201 ARG B HH21   1 
ATOM   10395 H HH22   . ARG B 1 201 ? -30.430 22.150  -1.514  1.00 54.35  ? 201 ARG B HH22   1 
ATOM   10396 N N      . GLN B 1 202 ? -28.113 28.455  1.338   1.00 27.37  ? 202 GLN B N      1 
ATOM   10397 C CA     . GLN B 1 202 ? -28.897 28.980  2.452   1.00 32.06  ? 202 GLN B CA     1 
ATOM   10398 C C      . GLN B 1 202 ? -30.313 29.347  2.002   1.00 30.79  ? 202 GLN B C      1 
ATOM   10399 O O      . GLN B 1 202 ? -31.296 28.978  2.646   1.00 32.75  ? 202 GLN B O      1 
ATOM   10400 C CB     . GLN B 1 202 ? -28.185 30.187  3.053   1.00 35.96  ? 202 GLN B CB     1 
ATOM   10401 C CG     . GLN B 1 202 ? -28.798 30.732  4.328   1.00 48.39  ? 202 GLN B CG     1 
ATOM   10402 C CD     . GLN B 1 202 ? -28.072 31.972  4.810   1.00 59.55  ? 202 GLN B CD     1 
ATOM   10403 O OE1    . GLN B 1 202 ? -28.120 33.021  4.167   1.00 57.33  ? 202 GLN B OE1    1 
ATOM   10404 N NE2    . GLN B 1 202 ? -27.375 31.852  5.934   1.00 68.96  ? 202 GLN B NE2    1 
ATOM   10405 H H      . GLN B 1 202 ? -27.404 28.909  1.164   1.00 32.85  ? 202 GLN B H      1 
ATOM   10406 H HA     . GLN B 1 202 ? -28.967 28.299  3.139   1.00 38.47  ? 202 GLN B HA     1 
ATOM   10407 H HB2    . GLN B 1 202 ? -27.270 29.936  3.254   1.00 43.15  ? 202 GLN B HB2    1 
ATOM   10408 H HB3    . GLN B 1 202 ? -28.188 30.903  2.399   1.00 43.15  ? 202 GLN B HB3    1 
ATOM   10409 H HG2    . GLN B 1 202 ? -29.724 30.968  4.163   1.00 58.07  ? 202 GLN B HG2    1 
ATOM   10410 H HG3    . GLN B 1 202 ? -28.742 30.058  5.023   1.00 58.07  ? 202 GLN B HG3    1 
ATOM   10411 H HE21   . GLN B 1 202 ? -27.352 31.098  6.348   1.00 82.75  ? 202 GLN B HE21   1 
ATOM   10412 H HE22   . GLN B 1 202 ? -26.946 32.528  6.248   1.00 82.75  ? 202 GLN B HE22   1 
ATOM   10413 N N      . LEU B 1 203 ? -30.418 30.047  0.879   1.00 29.07  ? 203 LEU B N      1 
ATOM   10414 C CA     . LEU B 1 203 ? -31.719 30.461  0.366   1.00 34.23  ? 203 LEU B CA     1 
ATOM   10415 C C      . LEU B 1 203 ? -32.554 29.258  -0.072  1.00 37.22  ? 203 LEU B C      1 
ATOM   10416 O O      . LEU B 1 203 ? -33.752 29.186  0.202   1.00 32.88  ? 203 LEU B O      1 
ATOM   10417 C CB     . LEU B 1 203 ? -31.543 31.435  -0.798  1.00 35.65  ? 203 LEU B CB     1 
ATOM   10418 C CG     . LEU B 1 203 ? -32.828 31.957  -1.443  1.00 35.60  ? 203 LEU B CG     1 
ATOM   10419 C CD1    . LEU B 1 203 ? -33.696 32.676  -0.422  1.00 36.94  ? 203 LEU B CD1    1 
ATOM   10420 C CD2    . LEU B 1 203 ? -32.493 32.876  -2.600  1.00 36.21  ? 203 LEU B CD2    1 
ATOM   10421 H H      . LEU B 1 203 ? -29.752 30.295  0.395   1.00 34.89  ? 203 LEU B H      1 
ATOM   10422 H HA     . LEU B 1 203 ? -32.202 30.919  1.071   1.00 41.08  ? 203 LEU B HA     1 
ATOM   10423 H HB2    . LEU B 1 203 ? -31.048 32.205  -0.478  1.00 42.78  ? 203 LEU B HB2    1 
ATOM   10424 H HB3    . LEU B 1 203 ? -31.032 30.990  -1.492  1.00 42.78  ? 203 LEU B HB3    1 
ATOM   10425 H HG     . LEU B 1 203 ? -33.335 31.209  -1.794  1.00 42.72  ? 203 LEU B HG     1 
ATOM   10426 H HD11   . LEU B 1 203 ? -34.443 33.092  -0.881  1.00 44.33  ? 203 LEU B HD11   1 
ATOM   10427 H HD12   . LEU B 1 203 ? -34.023 32.032  0.225   1.00 44.33  ? 203 LEU B HD12   1 
ATOM   10428 H HD13   . LEU B 1 203 ? -33.163 33.353  0.023   1.00 44.33  ? 203 LEU B HD13   1 
ATOM   10429 H HD21   . LEU B 1 203 ? -33.316 33.145  -3.038  1.00 43.45  ? 203 LEU B HD21   1 
ATOM   10430 H HD22   . LEU B 1 203 ? -32.028 33.656  -2.259  1.00 43.45  ? 203 LEU B HD22   1 
ATOM   10431 H HD23   . LEU B 1 203 ? -31.926 32.400  -3.225  1.00 43.45  ? 203 LEU B HD23   1 
ATOM   10432 N N      . CYS B 1 204 ? -31.926 28.301  -0.746  1.00 31.41  ? 204 CYS B N      1 
ATOM   10433 C CA     . CYS B 1 204 ? -32.654 27.123  -1.194  1.00 29.74  ? 204 CYS B CA     1 
ATOM   10434 C C      . CYS B 1 204 ? -33.085 26.232  -0.031  1.00 30.72  ? 204 CYS B C      1 
ATOM   10435 O O      . CYS B 1 204 ? -34.165 25.648  -0.071  1.00 32.25  ? 204 CYS B O      1 
ATOM   10436 C CB     . CYS B 1 204 ? -31.812 26.331  -2.190  1.00 33.14  ? 204 CYS B CB     1 
ATOM   10437 S SG     . CYS B 1 204 ? -31.741 27.137  -3.801  1.00 30.68  ? 204 CYS B SG     1 
ATOM   10438 H H      . CYS B 1 204 ? -31.092 28.309  -0.954  1.00 37.69  ? 204 CYS B H      1 
ATOM   10439 H HA     . CYS B 1 204 ? -33.457 27.412  -1.655  1.00 35.69  ? 204 CYS B HA     1 
ATOM   10440 H HB2    . CYS B 1 204 ? -30.907 26.252  -1.851  1.00 39.77  ? 204 CYS B HB2    1 
ATOM   10441 H HB3    . CYS B 1 204 ? -32.203 25.453  -2.309  1.00 39.77  ? 204 CYS B HB3    1 
ATOM   10442 H HG     . CYS B 1 204 ? -31.086 26.473  -4.553  1.00 36.82  ? 204 CYS B HG     1 
ATOM   10443 N N      . ASP B 1 205 ? -32.248 26.129  0.998   1.00 31.23  ? 205 ASP B N      1 
ATOM   10444 C CA     . ASP B 1 205 ? -32.600 25.372  2.197   1.00 31.28  ? 205 ASP B CA     1 
ATOM   10445 C C      . ASP B 1 205 ? -33.860 25.941  2.858   1.00 36.56  ? 205 ASP B C      1 
ATOM   10446 O O      . ASP B 1 205 ? -34.701 25.192  3.347   1.00 30.92  ? 205 ASP B O      1 
ATOM   10447 C CB     . ASP B 1 205 ? -31.452 25.380  3.209   1.00 28.83  ? 205 ASP B CB     1 
ATOM   10448 C CG     . ASP B 1 205 ? -30.356 24.388  2.870   1.00 35.92  ? 205 ASP B CG     1 
ATOM   10449 O OD1    . ASP B 1 205 ? -30.553 23.560  1.960   1.00 39.07  ? 205 ASP B OD1    1 
ATOM   10450 O OD2    . ASP B 1 205 ? -29.298 24.431  3.532   1.00 41.36  ? 205 ASP B OD2    1 
ATOM   10451 H H      . ASP B 1 205 ? -31.468 26.489  1.027   1.00 37.48  ? 205 ASP B H      1 
ATOM   10452 H HA     . ASP B 1 205 ? -32.790 24.454  1.950   1.00 37.54  ? 205 ASP B HA     1 
ATOM   10453 H HB2    . ASP B 1 205 ? -31.057 26.266  3.231   1.00 34.59  ? 205 ASP B HB2    1 
ATOM   10454 H HB3    . ASP B 1 205 ? -31.802 25.152  4.084   1.00 34.59  ? 205 ASP B HB3    1 
ATOM   10455 N N      . LYS B 1 206 ? -33.972 27.267  2.875   1.00 35.79  ? 206 LYS B N      1 
ATOM   10456 C CA     . LYS B 1 206 ? -35.151 27.936  3.423   1.00 36.92  ? 206 LYS B CA     1 
ATOM   10457 C C      . LYS B 1 206 ? -36.435 27.436  2.774   1.00 39.12  ? 206 LYS B C      1 
ATOM   10458 O O      . LYS B 1 206 ? -37.468 27.317  3.432   1.00 34.90  ? 206 LYS B O      1 
ATOM   10459 C CB     . LYS B 1 206 ? -35.048 29.451  3.230   1.00 41.21  ? 206 LYS B CB     1 
ATOM   10460 C CG     . LYS B 1 206 ? -34.640 30.223  4.476   1.00 54.13  ? 206 LYS B CG     1 
ATOM   10461 C CD     . LYS B 1 206 ? -34.627 31.738  4.232   1.00 57.98  ? 206 LYS B CD     1 
ATOM   10462 C CE     . LYS B 1 206 ? -36.019 32.283  3.912   1.00 65.83  ? 206 LYS B CE     1 
ATOM   10463 N NZ     . LYS B 1 206 ? -36.041 33.770  3.798   1.00 71.60  ? 206 LYS B NZ     1 
ATOM   10464 H H      . LYS B 1 206 ? -33.373 27.806  2.573   1.00 42.95  ? 206 LYS B H      1 
ATOM   10465 H HA     . LYS B 1 206 ? -35.204 27.756  4.375   1.00 44.31  ? 206 LYS B HA     1 
ATOM   10466 H HB2    . LYS B 1 206 ? -34.387 29.635  2.546   1.00 49.45  ? 206 LYS B HB2    1 
ATOM   10467 H HB3    . LYS B 1 206 ? -35.914 29.778  2.944   1.00 49.45  ? 206 LYS B HB3    1 
ATOM   10468 H HG2    . LYS B 1 206 ? -35.272 30.036  5.188   1.00 64.96  ? 206 LYS B HG2    1 
ATOM   10469 H HG3    . LYS B 1 206 ? -33.747 29.951  4.741   1.00 64.96  ? 206 LYS B HG3    1 
ATOM   10470 H HD2    . LYS B 1 206 ? -34.304 32.186  5.029   1.00 69.58  ? 206 LYS B HD2    1 
ATOM   10471 H HD3    . LYS B 1 206 ? -34.046 31.934  3.480   1.00 69.58  ? 206 LYS B HD3    1 
ATOM   10472 H HE2    . LYS B 1 206 ? -36.318 31.919  3.065   1.00 79.00  ? 206 LYS B HE2    1 
ATOM   10473 H HE3    . LYS B 1 206 ? -36.631 32.026  4.620   1.00 79.00  ? 206 LYS B HE3    1 
ATOM   10474 H HZ1    . LYS B 1 206 ? -36.866 34.048  3.612   1.00 85.92  ? 206 LYS B HZ1    1 
ATOM   10475 H HZ2    . LYS B 1 206 ? -35.778 34.138  4.565   1.00 85.92  ? 206 LYS B HZ2    1 
ATOM   10476 H HZ3    . LYS B 1 206 ? -35.493 34.033  3.148   1.00 85.92  ? 206 LYS B HZ3    1 
ATOM   10477 N N      . HIS B 1 207 ? -36.355 27.131  1.481   1.00 34.90  ? 207 HIS B N      1 
ATOM   10478 C CA     . HIS B 1 207 ? -37.541 26.845  0.676   1.00 35.00  ? 207 HIS B CA     1 
ATOM   10479 C C      . HIS B 1 207 ? -37.655 25.385  0.226   1.00 35.28  ? 207 HIS B C      1 
ATOM   10480 O O      . HIS B 1 207 ? -38.581 25.035  -0.505  1.00 39.04  ? 207 HIS B O      1 
ATOM   10481 C CB     . HIS B 1 207 ? -37.554 27.761  -0.552  1.00 36.74  ? 207 HIS B CB     1 
ATOM   10482 C CG     . HIS B 1 207 ? -37.763 29.206  -0.231  1.00 38.99  ? 207 HIS B CG     1 
ATOM   10483 N ND1    . HIS B 1 207 ? -36.719 30.102  -0.075  1.00 41.59  ? 207 HIS B ND1    1 
ATOM   10484 C CD2    . HIS B 1 207 ? -38.892 29.926  -0.035  1.00 37.27  ? 207 HIS B CD2    1 
ATOM   10485 C CE1    . HIS B 1 207 ? -37.199 31.296  0.198   1.00 41.32  ? 207 HIS B CE1    1 
ATOM   10486 N NE2    . HIS B 1 207 ? -38.521 31.219  0.228   1.00 45.82  ? 207 HIS B NE2    1 
ATOM   10487 H H      . HIS B 1 207 ? -35.618 27.083  1.041   1.00 41.88  ? 207 HIS B H      1 
ATOM   10488 H HA     . HIS B 1 207 ? -38.334 27.050  1.194   1.00 42.00  ? 207 HIS B HA     1 
ATOM   10489 H HB2    . HIS B 1 207 ? -36.703 27.680  -1.010  1.00 44.09  ? 207 HIS B HB2    1 
ATOM   10490 H HB3    . HIS B 1 207 ? -38.272 27.484  -1.142  1.00 44.09  ? 207 HIS B HB3    1 
ATOM   10491 H HD1    . HIS B 1 207 ? -35.884 29.908  -0.147  1.00 49.91  ? 207 HIS B HD1    1 
ATOM   10492 H HD2    . HIS B 1 207 ? -39.760 29.606  -0.075  1.00 44.73  ? 207 HIS B HD2    1 
ATOM   10493 H HE1    . HIS B 1 207 ? -36.695 32.064  0.346   1.00 49.58  ? 207 HIS B HE1    1 
ATOM   10494 N N      . GLY B 1 208 ? -36.723 24.538  0.658   1.00 33.69  ? 208 GLY B N      1 
ATOM   10495 C CA     . GLY B 1 208 ? -36.746 23.123  0.310   1.00 35.50  ? 208 GLY B CA     1 
ATOM   10496 C C      . GLY B 1 208 ? -36.416 22.839  -1.150  1.00 35.90  ? 208 GLY B C      1 
ATOM   10497 O O      . GLY B 1 208 ? -36.840 21.825  -1.705  1.00 40.72  ? 208 GLY B O      1 
ATOM   10498 H H      . GLY B 1 208 ? -36.061 24.761  1.159   1.00 40.42  ? 208 GLY B H      1 
ATOM   10499 H HA2    . GLY B 1 208 ? -36.104 22.650  0.862   1.00 42.59  ? 208 GLY B HA2    1 
ATOM   10500 H HA3    . GLY B 1 208 ? -37.628 22.764  0.496   1.00 42.59  ? 208 GLY B HA3    1 
ATOM   10501 N N      . ILE B 1 209 ? -35.652 23.733  -1.767  1.00 30.96  ? 209 ILE B N      1 
ATOM   10502 C CA     . ILE B 1 209 ? -35.275 23.597  -3.170  1.00 35.89  ? 209 ILE B CA     1 
ATOM   10503 C C      . ILE B 1 209 ? -33.938 22.874  -3.306  1.00 31.22  ? 209 ILE B C      1 
ATOM   10504 O O      . ILE B 1 209 ? -33.005 23.137  -2.552  1.00 30.99  ? 209 ILE B O      1 
ATOM   10505 C CB     . ILE B 1 209 ? -35.182 24.977  -3.852  1.00 35.08  ? 209 ILE B CB     1 
ATOM   10506 C CG1    . ILE B 1 209 ? -36.536 25.684  -3.791  1.00 34.61  ? 209 ILE B CG1    1 
ATOM   10507 C CG2    . ILE B 1 209 ? -34.726 24.837  -5.304  1.00 35.24  ? 209 ILE B CG2    1 
ATOM   10508 C CD1    . ILE B 1 209 ? -36.476 27.148  -4.178  1.00 32.21  ? 209 ILE B CD1    1 
ATOM   10509 H H      . ILE B 1 209 ? -35.334 24.437  -1.390  1.00 37.15  ? 209 ILE B H      1 
ATOM   10510 H HA     . ILE B 1 209 ? -35.948 23.079  -3.638  1.00 43.07  ? 209 ILE B HA     1 
ATOM   10511 H HB     . ILE B 1 209 ? -34.531 25.514  -3.374  1.00 42.10  ? 209 ILE B HB     1 
ATOM   10512 H HG12   . ILE B 1 209 ? -37.147 25.241  -4.400  1.00 41.53  ? 209 ILE B HG12   1 
ATOM   10513 H HG13   . ILE B 1 209 ? -36.880 25.634  -2.886  1.00 41.53  ? 209 ILE B HG13   1 
ATOM   10514 H HG21   . ILE B 1 209 ? -34.859 25.680  -5.763  1.00 42.29  ? 209 ILE B HG21   1 
ATOM   10515 H HG22   . ILE B 1 209 ? -33.785 24.602  -5.322  1.00 42.29  ? 209 ILE B HG22   1 
ATOM   10516 H HG23   . ILE B 1 209 ? -35.250 24.143  -5.733  1.00 42.29  ? 209 ILE B HG23   1 
ATOM   10517 H HD11   . ILE B 1 209 ? -37.310 27.574  -3.927  1.00 38.65  ? 209 ILE B HD11   1 
ATOM   10518 H HD12   . ILE B 1 209 ? -35.737 27.567  -3.710  1.00 38.65  ? 209 ILE B HD12   1 
ATOM   10519 H HD13   . ILE B 1 209 ? -36.344 27.219  -5.136  1.00 38.65  ? 209 ILE B HD13   1 
ATOM   10520 N N      . LYS B 1 210 ? -33.845 21.973  -4.279  1.00 34.29  ? 210 LYS B N      1 
ATOM   10521 C CA     . LYS B 1 210 ? -32.611 21.227  -4.501  1.00 34.79  ? 210 LYS B CA     1 
ATOM   10522 C C      . LYS B 1 210 ? -31.655 21.979  -5.422  1.00 31.77  ? 210 LYS B C      1 
ATOM   10523 O O      . LYS B 1 210 ? -32.080 22.714  -6.319  1.00 27.64  ? 210 LYS B O      1 
ATOM   10524 C CB     . LYS B 1 210 ? -32.915 19.848  -5.086  1.00 34.83  ? 210 LYS B CB     1 
ATOM   10525 C CG     . LYS B 1 210 ? -33.579 18.890  -4.113  1.00 37.37  ? 210 LYS B CG     1 
ATOM   10526 C CD     . LYS B 1 210 ? -33.819 17.557  -4.791  1.00 50.97  ? 210 LYS B CD     1 
ATOM   10527 C CE     . LYS B 1 210 ? -34.351 16.511  -3.833  1.00 78.29  ? 210 LYS B CE     1 
ATOM   10528 N NZ     . LYS B 1 210 ? -34.544 15.202  -4.524  1.00 67.23  ? 210 LYS B NZ     1 
ATOM   10529 H H      . LYS B 1 210 ? -34.481 21.775  -4.823  1.00 41.14  ? 210 LYS B H      1 
ATOM   10530 H HA     . LYS B 1 210 ? -32.164 21.093  -3.651  1.00 41.75  ? 210 LYS B HA     1 
ATOM   10531 H HB2    . LYS B 1 210 ? -33.509 19.956  -5.845  1.00 41.80  ? 210 LYS B HB2    1 
ATOM   10532 H HB3    . LYS B 1 210 ? -32.083 19.443  -5.377  1.00 41.80  ? 210 LYS B HB3    1 
ATOM   10533 H HG2    . LYS B 1 210 ? -32.999 18.748  -3.348  1.00 44.85  ? 210 LYS B HG2    1 
ATOM   10534 H HG3    . LYS B 1 210 ? -34.434 19.252  -3.831  1.00 44.85  ? 210 LYS B HG3    1 
ATOM   10535 H HD2    . LYS B 1 210 ? -34.470 17.674  -5.501  1.00 61.16  ? 210 LYS B HD2    1 
ATOM   10536 H HD3    . LYS B 1 210 ? -32.982 17.232  -5.157  1.00 61.16  ? 210 LYS B HD3    1 
ATOM   10537 H HE2    . LYS B 1 210 ? -33.717 16.384  -3.110  1.00 93.95  ? 210 LYS B HE2    1 
ATOM   10538 H HE3    . LYS B 1 210 ? -35.208 16.801  -3.483  1.00 93.95  ? 210 LYS B HE3    1 
ATOM   10539 H HZ1    . LYS B 1 210 ? -34.856 14.598  -3.950  1.00 80.68  ? 210 LYS B HZ1    1 
ATOM   10540 H HZ2    . LYS B 1 210 ? -35.125 15.294  -5.192  1.00 80.68  ? 210 LYS B HZ2    1 
ATOM   10541 H HZ3    . LYS B 1 210 ? -33.768 14.915  -4.853  1.00 80.68  ? 210 LYS B HZ3    1 
ATOM   10542 N N      . VAL B 1 211 ? -30.362 21.781  -5.179  1.00 30.50  ? 211 VAL B N      1 
ATOM   10543 C CA     . VAL B 1 211 ? -29.303 22.374  -5.989  1.00 26.93  ? 211 VAL B CA     1 
ATOM   10544 C C      . VAL B 1 211 ? -28.437 21.258  -6.560  1.00 26.03  ? 211 VAL B C      1 
ATOM   10545 O O      . VAL B 1 211 ? -27.939 20.412  -5.814  1.00 26.87  ? 211 VAL B O      1 
ATOM   10546 C CB     . VAL B 1 211 ? -28.429 23.337  -5.162  1.00 30.34  ? 211 VAL B CB     1 
ATOM   10547 C CG1    . VAL B 1 211 ? -27.313 23.915  -6.009  1.00 27.83  ? 211 VAL B CG1    1 
ATOM   10548 C CG2    . VAL B 1 211 ? -29.285 24.448  -4.571  1.00 30.18  ? 211 VAL B CG2    1 
ATOM   10549 H H      . VAL B 1 211 ? -30.067 21.295  -4.534  1.00 36.60  ? 211 VAL B H      1 
ATOM   10550 H HA     . VAL B 1 211 ? -29.687 22.870  -6.728  1.00 32.32  ? 211 VAL B HA     1 
ATOM   10551 H HB     . VAL B 1 211 ? -28.026 22.847  -4.429  1.00 36.41  ? 211 VAL B HB     1 
ATOM   10552 H HG11   . VAL B 1 211 ? -26.920 24.668  -5.540  1.00 33.40  ? 211 VAL B HG11   1 
ATOM   10553 H HG12   . VAL B 1 211 ? -26.640 23.233  -6.159  1.00 33.40  ? 211 VAL B HG12   1 
ATOM   10554 H HG13   . VAL B 1 211 ? -27.681 24.211  -6.856  1.00 33.40  ? 211 VAL B HG13   1 
ATOM   10555 H HG21   . VAL B 1 211 ? -28.713 25.064  -4.087  1.00 36.22  ? 211 VAL B HG21   1 
ATOM   10556 H HG22   . VAL B 1 211 ? -29.734 24.911  -5.294  1.00 36.22  ? 211 VAL B HG22   1 
ATOM   10557 H HG23   . VAL B 1 211 ? -29.939 24.059  -3.969  1.00 36.22  ? 211 VAL B HG23   1 
ATOM   10558 N N      . PHE B 1 212 ? -28.274 21.255  -7.878  1.00 25.53  ? 212 PHE B N      1 
ATOM   10559 C CA     . PHE B 1 212 ? -27.420 20.280  -8.552  1.00 24.42  ? 212 PHE B CA     1 
ATOM   10560 C C      . PHE B 1 212 ? -26.381 21.007  -9.389  1.00 25.77  ? 212 PHE B C      1 
ATOM   10561 O O      . PHE B 1 212 ? -26.717 21.894  -10.180 1.00 28.89  ? 212 PHE B O      1 
ATOM   10562 C CB     . PHE B 1 212 ? -28.248 19.343  -9.429  1.00 24.40  ? 212 PHE B CB     1 
ATOM   10563 C CG     . PHE B 1 212 ? -29.140 18.423  -8.649  1.00 27.93  ? 212 PHE B CG     1 
ATOM   10564 C CD1    . PHE B 1 212 ? -28.607 17.354  -7.956  1.00 28.36  ? 212 PHE B CD1    1 
ATOM   10565 C CD2    . PHE B 1 212 ? -30.508 18.627  -8.613  1.00 30.19  ? 212 PHE B CD2    1 
ATOM   10566 C CE1    . PHE B 1 212 ? -29.425 16.497  -7.234  1.00 33.89  ? 212 PHE B CE1    1 
ATOM   10567 C CE2    . PHE B 1 212 ? -31.329 17.778  -7.894  1.00 33.14  ? 212 PHE B CE2    1 
ATOM   10568 C CZ     . PHE B 1 212 ? -30.786 16.712  -7.203  1.00 35.06  ? 212 PHE B CZ     1 
ATOM   10569 H H      . PHE B 1 212 ? -28.651 21.814  -8.412  1.00 30.64  ? 212 PHE B H      1 
ATOM   10570 H HA     . PHE B 1 212 ? -26.950 19.741  -7.897  1.00 29.31  ? 212 PHE B HA     1 
ATOM   10571 H HB2    . PHE B 1 212 ? -28.809 19.876  -10.014 1.00 29.28  ? 212 PHE B HB2    1 
ATOM   10572 H HB3    . PHE B 1 212 ? -27.646 18.796  -9.958  1.00 29.28  ? 212 PHE B HB3    1 
ATOM   10573 H HD1    . PHE B 1 212 ? -27.689 17.206  -7.974  1.00 34.03  ? 212 PHE B HD1    1 
ATOM   10574 H HD2    . PHE B 1 212 ? -30.879 19.344  -9.075  1.00 36.23  ? 212 PHE B HD2    1 
ATOM   10575 H HE1    . PHE B 1 212 ? -29.056 15.781  -6.770  1.00 40.67  ? 212 PHE B HE1    1 
ATOM   10576 H HE2    . PHE B 1 212 ? -32.247 17.925  -7.876  1.00 39.77  ? 212 PHE B HE2    1 
ATOM   10577 H HZ     . PHE B 1 212 ? -31.338 16.140  -6.720  1.00 42.07  ? 212 PHE B HZ     1 
ATOM   10578 N N      . TYR B 1 213 ? -25.118 20.643  -9.205  1.00 22.43  ? 213 TYR B N      1 
ATOM   10579 C CA     . TYR B 1 213 ? -24.045 21.321  -9.906  1.00 21.63  ? 213 TYR B CA     1 
ATOM   10580 C C      . TYR B 1 213 ? -23.825 20.700  -11.280 1.00 25.47  ? 213 TYR B C      1 
ATOM   10581 O O      . TYR B 1 213 ? -23.852 19.485  -11.426 1.00 25.10  ? 213 TYR B O      1 
ATOM   10582 C CB     . TYR B 1 213 ? -22.739 21.262  -9.115  1.00 23.77  ? 213 TYR B CB     1 
ATOM   10583 C CG     . TYR B 1 213 ? -22.670 22.142  -7.888  1.00 23.46  ? 213 TYR B CG     1 
ATOM   10584 C CD1    . TYR B 1 213 ? -23.790 22.809  -7.405  1.00 23.29  ? 213 TYR B CD1    1 
ATOM   10585 C CD2    . TYR B 1 213 ? -21.472 22.300  -7.210  1.00 24.01  ? 213 TYR B CD2    1 
ATOM   10586 C CE1    . TYR B 1 213 ? -23.706 23.608  -6.281  1.00 22.65  ? 213 TYR B CE1    1 
ATOM   10587 C CE2    . TYR B 1 213 ? -21.377 23.093  -6.105  1.00 22.90  ? 213 TYR B CE2    1 
ATOM   10588 C CZ     . TYR B 1 213 ? -22.491 23.747  -5.641  1.00 26.05  ? 213 TYR B CZ     1 
ATOM   10589 O OH     . TYR B 1 213 ? -22.376 24.532  -4.527  1.00 27.70  ? 213 TYR B OH     1 
ATOM   10590 H H      . TYR B 1 213 ? -24.860 20.010  -8.683  1.00 26.92  ? 213 TYR B H      1 
ATOM   10591 H HA     . TYR B 1 213 ? -24.292 22.246  -10.022 1.00 25.95  ? 213 TYR B HA     1 
ATOM   10592 H HB2    . TYR B 1 213 ? -22.600 20.347  -8.823  1.00 28.53  ? 213 TYR B HB2    1 
ATOM   10593 H HB3    . TYR B 1 213 ? -22.014 21.527  -9.702  1.00 28.53  ? 213 TYR B HB3    1 
ATOM   10594 H HD1    . TYR B 1 213 ? -24.606 22.716  -7.841  1.00 27.95  ? 213 TYR B HD1    1 
ATOM   10595 H HD2    . TYR B 1 213 ? -20.713 21.863  -7.522  1.00 28.82  ? 213 TYR B HD2    1 
ATOM   10596 H HE1    . TYR B 1 213 ? -24.458 24.055  -5.964  1.00 27.18  ? 213 TYR B HE1    1 
ATOM   10597 H HE2    . TYR B 1 213 ? -20.563 23.187  -5.666  1.00 27.48  ? 213 TYR B HE2    1 
ATOM   10598 H HH     . TYR B 1 213 ? -21.584 24.521  -4.248  1.00 33.25  ? 213 TYR B HH     1 
ATOM   10599 N N      . ASP B 1 214 ? -23.637 21.552  -12.281 1.00 26.05  ? 214 ASP B N      1 
ATOM   10600 C CA     . ASP B 1 214 ? -23.076 21.142  -13.563 1.00 27.48  ? 214 ASP B CA     1 
ATOM   10601 C C      . ASP B 1 214 ? -21.580 21.365  -13.404 1.00 26.70  ? 214 ASP B C      1 
ATOM   10602 O O      . ASP B 1 214 ? -21.087 22.465  -13.624 1.00 25.30  ? 214 ASP B O      1 
ATOM   10603 C CB     . ASP B 1 214 ? -23.674 21.957  -14.719 1.00 32.23  ? 214 ASP B CB     1 
ATOM   10604 C CG     . ASP B 1 214 ? -23.162 21.520  -16.086 1.00 38.71  ? 214 ASP B CG     1 
ATOM   10605 O OD1    . ASP B 1 214 ? -22.139 20.805  -16.150 1.00 36.21  ? 214 ASP B OD1    1 
ATOM   10606 O OD2    . ASP B 1 214 ? -23.786 21.906  -17.101 1.00 32.98  ? 214 ASP B OD2    1 
ATOM   10607 H H      . ASP B 1 214 ? -23.830 22.389  -12.241 1.00 31.26  ? 214 ASP B H      1 
ATOM   10608 H HA     . ASP B 1 214 ? -23.242 20.200  -13.722 1.00 32.97  ? 214 ASP B HA     1 
ATOM   10609 H HB2    . ASP B 1 214 ? -24.638 21.850  -14.713 1.00 38.68  ? 214 ASP B HB2    1 
ATOM   10610 H HB3    . ASP B 1 214 ? -23.445 22.892  -14.599 1.00 38.68  ? 214 ASP B HB3    1 
ATOM   10611 N N      . ALA B 1 215 ? -20.869 20.311  -13.011 1.00 21.89  ? 215 ALA B N      1 
ATOM   10612 C CA     . ALA B 1 215 ? -19.558 20.456  -12.379 1.00 28.29  ? 215 ALA B CA     1 
ATOM   10613 C C      . ALA B 1 215 ? -18.337 20.220  -13.281 1.00 25.02  ? 215 ALA B C      1 
ATOM   10614 O O      . ALA B 1 215 ? -17.259 19.934  -12.768 1.00 22.13  ? 215 ALA B O      1 
ATOM   10615 C CB     . ALA B 1 215 ? -19.485 19.498  -11.191 1.00 29.14  ? 215 ALA B CB     1 
ATOM   10616 H H      . ALA B 1 215 ? -21.125 19.495  -13.099 1.00 26.27  ? 215 ALA B H      1 
ATOM   10617 H HA     . ALA B 1 215 ? -19.485 21.357  -12.027 1.00 33.94  ? 215 ALA B HA     1 
ATOM   10618 H HB1    . ALA B 1 215 ? -18.649 19.636  -10.720 1.00 34.97  ? 215 ALA B HB1    1 
ATOM   10619 H HB2    . ALA B 1 215 ? -20.230 19.678  -10.597 1.00 34.97  ? 215 ALA B HB2    1 
ATOM   10620 H HB3    . ALA B 1 215 ? -19.537 18.586  -11.517 1.00 34.97  ? 215 ALA B HB3    1 
ATOM   10621 N N      . THR B 1 216 ? -18.480 20.373  -14.597 1.00 24.79  ? 216 THR B N      1 
ATOM   10622 C CA     . THR B 1 216 ? -17.459 19.866  -15.523 1.00 23.69  ? 216 THR B CA     1 
ATOM   10623 C C      . THR B 1 216 ? -16.077 20.499  -15.363 1.00 18.80  ? 216 THR B C      1 
ATOM   10624 O O      . THR B 1 216 ? -15.073 19.853  -15.642 1.00 22.01  ? 216 THR B O      1 
ATOM   10625 C CB     . THR B 1 216 ? -17.887 20.049  -16.994 1.00 25.90  ? 216 THR B CB     1 
ATOM   10626 O OG1    . THR B 1 216 ? -17.915 21.447  -17.321 1.00 27.73  ? 216 THR B OG1    1 
ATOM   10627 C CG2    . THR B 1 216 ? -19.254 19.422  -17.226 1.00 28.01  ? 216 THR B CG2    1 
ATOM   10628 H H      . THR B 1 216 ? -19.146 20.763  -14.976 1.00 29.74  ? 216 THR B H      1 
ATOM   10629 H HA     . THR B 1 216 ? -17.358 18.914  -15.369 1.00 28.42  ? 216 THR B HA     1 
ATOM   10630 H HB     . THR B 1 216 ? -17.248 19.601  -17.569 1.00 31.08  ? 216 THR B HB     1 
ATOM   10631 H HG1    . THR B 1 216 ? -18.147 21.550  -18.122 1.00 33.27  ? 216 THR B HG1    1 
ATOM   10632 H HG21   . THR B 1 216 ? -19.498 19.496  -18.162 1.00 33.61  ? 216 THR B HG21   1 
ATOM   10633 H HG22   . THR B 1 216 ? -19.234 18.484  -16.979 1.00 33.61  ? 216 THR B HG22   1 
ATOM   10634 H HG23   . THR B 1 216 ? -19.922 19.874  -16.690 1.00 33.61  ? 216 THR B HG23   1 
ATOM   10635 N N      . ARG B 1 217 ? -16.010 21.752  -14.922 1.00 19.53  ? 217 ARG B N      1 
ATOM   10636 C CA     . ARG B 1 217 ? -14.712 22.398  -14.718 1.00 17.32  ? 217 ARG B CA     1 
ATOM   10637 C C      . ARG B 1 217 ? -14.556 22.879  -13.274 1.00 17.80  ? 217 ARG B C      1 
ATOM   10638 O O      . ARG B 1 217 ? -14.051 23.978  -13.004 1.00 19.22  ? 217 ARG B O      1 
ATOM   10639 C CB     . ARG B 1 217 ? -14.537 23.536  -15.724 1.00 19.38  ? 217 ARG B CB     1 
ATOM   10640 C CG     . ARG B 1 217 ? -14.591 23.023  -17.170 1.00 19.11  ? 217 ARG B CG     1 
ATOM   10641 C CD     . ARG B 1 217 ? -14.195 24.068  -18.192 1.00 19.92  ? 217 ARG B CD     1 
ATOM   10642 N NE     . ARG B 1 217 ? -14.339 23.581  -19.567 1.00 18.16  ? 217 ARG B NE     1 
ATOM   10643 C CZ     . ARG B 1 217 ? -15.489 23.560  -20.235 1.00 24.09  ? 217 ARG B CZ     1 
ATOM   10644 N NH1    . ARG B 1 217 ? -16.609 23.992  -19.661 1.00 23.04  ? 217 ARG B NH1    1 
ATOM   10645 N NH2    . ARG B 1 217 ? -15.525 23.106  -21.482 1.00 22.31  ? 217 ARG B NH2    1 
ATOM   10646 H H      . ARG B 1 217 ? -16.689 22.245  -14.735 1.00 23.43  ? 217 ARG B H      1 
ATOM   10647 H HA     . ARG B 1 217 ? -14.004 21.762  -14.887 1.00 20.79  ? 217 ARG B HA     1 
ATOM   10648 H HB2    . ARG B 1 217 ? -15.251 24.181  -15.606 1.00 23.26  ? 217 ARG B HB2    1 
ATOM   10649 H HB3    . ARG B 1 217 ? -13.675 23.959  -15.584 1.00 23.26  ? 217 ARG B HB3    1 
ATOM   10650 H HG2    . ARG B 1 217 ? -13.983 22.273  -17.260 1.00 22.93  ? 217 ARG B HG2    1 
ATOM   10651 H HG3    . ARG B 1 217 ? -15.497 22.740  -17.369 1.00 22.93  ? 217 ARG B HG3    1 
ATOM   10652 H HD2    . ARG B 1 217 ? -14.755 24.852  -18.083 1.00 23.90  ? 217 ARG B HD2    1 
ATOM   10653 H HD3    . ARG B 1 217 ? -13.265 24.304  -18.057 1.00 23.90  ? 217 ARG B HD3    1 
ATOM   10654 H HE     . ARG B 1 217 ? -13.629 23.324  -19.979 1.00 21.79  ? 217 ARG B HE     1 
ATOM   10655 H HH11   . ARG B 1 217 ? -16.597 24.289  -18.855 1.00 27.65  ? 217 ARG B HH11   1 
ATOM   10656 H HH12   . ARG B 1 217 ? -17.349 23.974  -20.100 1.00 27.65  ? 217 ARG B HH12   1 
ATOM   10657 H HH21   . ARG B 1 217 ? -14.805 22.824  -21.858 1.00 26.77  ? 217 ARG B HH21   1 
ATOM   10658 H HH22   . ARG B 1 217 ? -16.269 23.090  -21.913 1.00 26.77  ? 217 ARG B HH22   1 
ATOM   10659 N N      . CYS B 1 218 ? -14.953 22.014  -12.344 1.00 18.60  ? 218 CYS B N      1 
ATOM   10660 C CA     . CYS B 1 218 ? -14.962 22.354  -10.924 1.00 20.38  ? 218 CYS B CA     1 
ATOM   10661 C C      . CYS B 1 218 ? -13.560 22.546  -10.360 1.00 19.42  ? 218 CYS B C      1 
ATOM   10662 O O      . CYS B 1 218 ? -13.367 23.294  -9.400  1.00 17.88  ? 218 CYS B O      1 
ATOM   10663 C CB     . CYS B 1 218 ? -15.695 21.278  -10.127 1.00 20.71  ? 218 CYS B CB     1 
ATOM   10664 S SG     . CYS B 1 218 ? -14.981 19.605  -10.245 1.00 22.99  ? 218 CYS B SG     1 
ATOM   10665 H H      . CYS B 1 218 ? -15.225 21.215  -12.512 1.00 22.32  ? 218 CYS B H      1 
ATOM   10666 H HA     . CYS B 1 218 ? -15.444 23.188  -10.807 1.00 24.45  ? 218 CYS B HA     1 
ATOM   10667 H HB2    . CYS B 1 218 ? -15.691 21.532  -9.191  1.00 24.85  ? 218 CYS B HB2    1 
ATOM   10668 H HB3    . CYS B 1 218 ? -16.610 21.228  -10.446 1.00 24.85  ? 218 CYS B HB3    1 
ATOM   10669 H HG     . CYS B 1 218 ? -15.641 18.856  -9.580  1.00 27.59  ? 218 CYS B HG     1 
ATOM   10670 N N      . VAL B 1 219 ? -12.566 21.893  -10.949 1.00 18.07  ? 219 VAL B N      1 
ATOM   10671 C CA     . VAL B 1 219 ? -11.206 22.025  -10.429 1.00 16.53  ? 219 VAL B CA     1 
ATOM   10672 C C      . VAL B 1 219 ? -10.617 23.363  -10.879 1.00 18.33  ? 219 VAL B C      1 
ATOM   10673 O O      . VAL B 1 219 ? -9.959  24.048  -10.096 1.00 17.09  ? 219 VAL B O      1 
ATOM   10674 C CB     . VAL B 1 219 ? -10.303 20.864  -10.865 1.00 17.79  ? 219 VAL B CB     1 
ATOM   10675 C CG1    . VAL B 1 219 ? -8.938  20.983  -10.197 1.00 17.35  ? 219 VAL B CG1    1 
ATOM   10676 C CG2    . VAL B 1 219 ? -10.942 19.550  -10.482 1.00 17.90  ? 219 VAL B CG2    1 
ATOM   10677 H H      . VAL B 1 219 ? -12.645 21.379  -11.634 1.00 21.68  ? 219 VAL B H      1 
ATOM   10678 H HA     . VAL B 1 219 ? -11.236 22.023  -9.460  1.00 19.83  ? 219 VAL B HA     1 
ATOM   10679 H HB     . VAL B 1 219 ? -10.183 20.884  -11.827 1.00 21.35  ? 219 VAL B HB     1 
ATOM   10680 H HG11   . VAL B 1 219 ? -8.444  20.166  -10.359 1.00 20.82  ? 219 VAL B HG11   1 
ATOM   10681 H HG12   . VAL B 1 219 ? -8.462  21.738  -10.576 1.00 20.82  ? 219 VAL B HG12   1 
ATOM   10682 H HG13   . VAL B 1 219 ? -9.062  21.111  -9.244  1.00 20.82  ? 219 VAL B HG13   1 
ATOM   10683 H HG21   . VAL B 1 219 ? -10.321 18.830  -10.673 1.00 21.48  ? 219 VAL B HG21   1 
ATOM   10684 H HG22   . VAL B 1 219 ? -11.150 19.565  -9.535  1.00 21.48  ? 219 VAL B HG22   1 
ATOM   10685 H HG23   . VAL B 1 219 ? -11.755 19.431  -10.997 1.00 21.48  ? 219 VAL B HG23   1 
ATOM   10686 N N      . GLU B 1 220 ? -10.863 23.746  -12.129 1.00 18.29  ? 220 GLU B N      1 
ATOM   10687 C CA     . GLU B 1 220 ? -10.520 25.091  -12.577 1.00 16.74  ? 220 GLU B CA     1 
ATOM   10688 C C      . GLU B 1 220 ? -11.199 26.115  -11.656 1.00 18.32  ? 220 GLU B C      1 
ATOM   10689 O O      . GLU B 1 220 ? -10.587 27.091  -11.239 1.00 17.00  ? 220 GLU B O      1 
ATOM   10690 C CB     . GLU B 1 220 ? -10.940 25.317  -14.032 1.00 20.01  ? 220 GLU B CB     1 
ATOM   10691 C CG     . GLU B 1 220 ? -10.096 24.542  -15.055 1.00 22.59  ? 220 GLU B CG     1 
ATOM   10692 C CD     . GLU B 1 220 ? -10.685 24.595  -16.449 1.00 26.34  ? 220 GLU B CD     1 
ATOM   10693 O OE1    . GLU B 1 220 ? -10.336 23.723  -17.284 1.00 24.23  ? 220 GLU B OE1    1 
ATOM   10694 O OE2    . GLU B 1 220 ? -11.507 25.504  -16.698 1.00 22.80  ? 220 GLU B OE2    1 
ATOM   10695 H H      . GLU B 1 220 ? -11.224 23.251  -12.732 1.00 21.95  ? 220 GLU B H      1 
ATOM   10696 H HA     . GLU B 1 220 ? -9.560  25.215  -12.515 1.00 20.08  ? 220 GLU B HA     1 
ATOM   10697 H HB2    . GLU B 1 220 ? -11.863 25.037  -14.137 1.00 24.02  ? 220 GLU B HB2    1 
ATOM   10698 H HB3    . GLU B 1 220 ? -10.859 26.262  -14.237 1.00 24.02  ? 220 GLU B HB3    1 
ATOM   10699 H HG2    . GLU B 1 220 ? -9.207  24.927  -15.089 1.00 27.10  ? 220 GLU B HG2    1 
ATOM   10700 H HG3    . GLU B 1 220 ? -10.046 23.612  -14.785 1.00 27.10  ? 220 GLU B HG3    1 
ATOM   10701 N N      . ASN B 1 221 ? -12.454 25.863  -11.315 1.00 18.86  ? 221 ASN B N      1 
ATOM   10702 C CA     . ASN B 1 221 ? -13.184 26.765  -10.432 1.00 18.80  ? 221 ASN B CA     1 
ATOM   10703 C C      . ASN B 1 221 ? -12.520 26.862  -9.062  1.00 15.86  ? 221 ASN B C      1 
ATOM   10704 O O      . ASN B 1 221 ? -12.332 27.963  -8.528  1.00 16.68  ? 221 ASN B O      1 
ATOM   10705 C CB     . ASN B 1 221 ? -14.629 26.310  -10.273 1.00 16.71  ? 221 ASN B CB     1 
ATOM   10706 C CG     . ASN B 1 221 ? -15.514 27.409  -9.726  1.00 23.25  ? 221 ASN B CG     1 
ATOM   10707 O OD1    . ASN B 1 221 ? -16.081 28.186  -10.484 1.00 18.69  ? 221 ASN B OD1    1 
ATOM   10708 N ND2    . ASN B 1 221 ? -15.612 27.499  -8.400  1.00 18.15  ? 221 ASN B ND2    1 
ATOM   10709 H H      . ASN B 1 221 ? -12.906 25.180  -11.579 1.00 22.63  ? 221 ASN B H      1 
ATOM   10710 H HA     . ASN B 1 221 ? -13.191 27.652  -10.824 1.00 22.56  ? 221 ASN B HA     1 
ATOM   10711 H HB2    . ASN B 1 221 ? -14.976 26.045  -11.139 1.00 20.05  ? 221 ASN B HB2    1 
ATOM   10712 H HB3    . ASN B 1 221 ? -14.661 25.562  -9.657  1.00 20.05  ? 221 ASN B HB3    1 
ATOM   10713 H HD21   . ASN B 1 221 ? -16.104 28.109  -8.046  1.00 21.78  ? 221 ASN B HD21   1 
ATOM   10714 H HD22   . ASN B 1 221 ? -15.183 26.947  -7.899  1.00 21.78  ? 221 ASN B HD22   1 
ATOM   10715 N N      . ALA B 1 222 ? -12.139 25.709  -8.513  1.00 17.68  ? 222 ALA B N      1 
ATOM   10716 C CA     . ALA B 1 222 ? -11.447 25.659  -7.223  1.00 18.14  ? 222 ALA B CA     1 
ATOM   10717 C C      . ALA B 1 222 ? -10.155 26.473  -7.259  1.00 19.46  ? 222 ALA B C      1 
ATOM   10718 O O      . ALA B 1 222 ? -9.819  27.142  -6.282  1.00 17.74  ? 222 ALA B O      1 
ATOM   10719 C CB     . ALA B 1 222 ? -11.156 24.214  -6.821  1.00 16.79  ? 222 ALA B CB     1 
ATOM   10720 H H      . ALA B 1 222 ? -12.270 24.937  -8.869  1.00 21.21  ? 222 ALA B H      1 
ATOM   10721 H HA     . ALA B 1 222 ? -12.022 26.046  -6.544  1.00 21.77  ? 222 ALA B HA     1 
ATOM   10722 H HB1    . ALA B 1 222 ? -10.699 24.211  -5.965  1.00 20.15  ? 222 ALA B HB1    1 
ATOM   10723 H HB2    . ALA B 1 222 ? -11.994 23.731  -6.751  1.00 20.15  ? 222 ALA B HB2    1 
ATOM   10724 H HB3    . ALA B 1 222 ? -10.594 23.805  -7.498  1.00 20.15  ? 222 ALA B HB3    1 
ATOM   10725 N N      . TYR B 1 223 ? -9.426  26.420  -8.375  1.00 16.88  ? 223 TYR B N      1 
ATOM   10726 C CA     . TYR B 1 223 ? -8.203  27.206  -8.489  1.00 15.29  ? 223 TYR B CA     1 
ATOM   10727 C C      . TYR B 1 223 ? -8.502  28.716  -8.405  1.00 17.36  ? 223 TYR B C      1 
ATOM   10728 O O      . TYR B 1 223 ? -7.805  29.456  -7.702  1.00 19.59  ? 223 TYR B O      1 
ATOM   10729 C CB     . TYR B 1 223 ? -7.435  26.906  -9.785  1.00 17.84  ? 223 TYR B CB     1 
ATOM   10730 C CG     . TYR B 1 223 ? -6.259  27.833  -9.875  1.00 17.40  ? 223 TYR B CG     1 
ATOM   10731 C CD1    . TYR B 1 223 ? -5.113  27.585  -9.137  1.00 18.81  ? 223 TYR B CD1    1 
ATOM   10732 C CD2    . TYR B 1 223 ? -6.327  29.004  -10.618 1.00 20.96  ? 223 TYR B CD2    1 
ATOM   10733 C CE1    . TYR B 1 223 ? -4.050  28.458  -9.161  1.00 22.11  ? 223 TYR B CE1    1 
ATOM   10734 C CE2    . TYR B 1 223 ? -5.268  29.888  -10.655 1.00 19.95  ? 223 TYR B CE2    1 
ATOM   10735 C CZ     . TYR B 1 223 ? -4.133  29.611  -9.920  1.00 22.95  ? 223 TYR B CZ     1 
ATOM   10736 O OH     . TYR B 1 223 ? -3.074  30.473  -9.935  1.00 22.43  ? 223 TYR B OH     1 
ATOM   10737 H H      . TYR B 1 223 ? -9.615  25.945  -9.067  1.00 20.26  ? 223 TYR B H      1 
ATOM   10738 H HA     . TYR B 1 223 ? -7.622  26.981  -7.746  1.00 18.35  ? 223 TYR B HA     1 
ATOM   10739 H HB2    . TYR B 1 223 ? -7.112  25.992  -9.771  1.00 21.41  ? 223 TYR B HB2    1 
ATOM   10740 H HB3    . TYR B 1 223 ? -8.011  27.057  -10.551 1.00 21.41  ? 223 TYR B HB3    1 
ATOM   10741 H HD1    . TYR B 1 223 ? -5.061  26.815  -8.618  1.00 22.57  ? 223 TYR B HD1    1 
ATOM   10742 H HD2    . TYR B 1 223 ? -7.097  29.193  -11.104 1.00 25.15  ? 223 TYR B HD2    1 
ATOM   10743 H HE1    . TYR B 1 223 ? -3.282  28.275  -8.669  1.00 26.53  ? 223 TYR B HE1    1 
ATOM   10744 H HE2    . TYR B 1 223 ? -5.321  30.664  -11.164 1.00 23.94  ? 223 TYR B HE2    1 
ATOM   10745 H HH     . TYR B 1 223 ? -3.251  31.137  -10.418 1.00 26.92  ? 223 TYR B HH     1 
ATOM   10746 N N      . PHE B 1 224 ? -9.540  29.179  -9.095  1.00 18.95  ? 224 PHE B N      1 
ATOM   10747 C CA     . PHE B 1 224 ? -9.883  30.602  -9.031  1.00 15.08  ? 224 PHE B CA     1 
ATOM   10748 C C      . PHE B 1 224 ? -10.277 31.015  -7.607  1.00 16.79  ? 224 PHE B C      1 
ATOM   10749 O O      . PHE B 1 224 ? -9.991  32.133  -7.182  1.00 18.77  ? 224 PHE B O      1 
ATOM   10750 C CB     . PHE B 1 224 ? -11.015 30.945  -9.997  1.00 16.69  ? 224 PHE B CB     1 
ATOM   10751 C CG     . PHE B 1 224 ? -10.570 31.073  -11.428 1.00 18.89  ? 224 PHE B CG     1 
ATOM   10752 C CD1    . PHE B 1 224 ? -9.787  32.148  -11.829 1.00 23.35  ? 224 PHE B CD1    1 
ATOM   10753 C CD2    . PHE B 1 224 ? -10.941 30.133  -12.372 1.00 21.36  ? 224 PHE B CD2    1 
ATOM   10754 C CE1    . PHE B 1 224 ? -9.377  32.281  -13.151 1.00 23.91  ? 224 PHE B CE1    1 
ATOM   10755 C CE2    . PHE B 1 224 ? -10.529 30.257  -13.699 1.00 22.06  ? 224 PHE B CE2    1 
ATOM   10756 C CZ     . PHE B 1 224 ? -9.747  31.322  -14.084 1.00 20.01  ? 224 PHE B CZ     1 
ATOM   10757 H H      . PHE B 1 224 ? -10.053 28.705  -9.597  1.00 22.74  ? 224 PHE B H      1 
ATOM   10758 H HA     . PHE B 1 224 ? -9.106  31.123  -9.286  1.00 18.09  ? 224 PHE B HA     1 
ATOM   10759 H HB2    . PHE B 1 224 ? -11.685 30.244  -9.956  1.00 20.03  ? 224 PHE B HB2    1 
ATOM   10760 H HB3    . PHE B 1 224 ? -11.407 31.791  -9.731  1.00 20.03  ? 224 PHE B HB3    1 
ATOM   10761 H HD1    . PHE B 1 224 ? -9.534  32.789  -11.204 1.00 28.02  ? 224 PHE B HD1    1 
ATOM   10762 H HD2    . PHE B 1 224 ? -11.465 29.408  -12.118 1.00 25.63  ? 224 PHE B HD2    1 
ATOM   10763 H HE1    . PHE B 1 224 ? -8.849  33.002  -13.406 1.00 28.70  ? 224 PHE B HE1    1 
ATOM   10764 H HE2    . PHE B 1 224 ? -10.781 29.617  -14.325 1.00 26.47  ? 224 PHE B HE2    1 
ATOM   10765 H HZ     . PHE B 1 224 ? -9.477  31.405  -14.970 1.00 24.01  ? 224 PHE B HZ     1 
ATOM   10766 N N      . ILE B 1 225 ? -10.931 30.114  -6.883  1.00 19.36  ? 225 ILE B N      1 
ATOM   10767 C CA     . ILE B 1 225 ? -11.299 30.377  -5.488  1.00 18.60  ? 225 ILE B CA     1 
ATOM   10768 C C      . ILE B 1 225 ? -10.026 30.506  -4.675  1.00 17.81  ? 225 ILE B C      1 
ATOM   10769 O O      . ILE B 1 225 ? -9.863  31.453  -3.904  1.00 17.70  ? 225 ILE B O      1 
ATOM   10770 C CB     . ILE B 1 225 ? -12.205 29.263  -4.915  1.00 16.61  ? 225 ILE B CB     1 
ATOM   10771 C CG1    . ILE B 1 225 ? -13.619 29.415  -5.476  1.00 15.38  ? 225 ILE B CG1    1 
ATOM   10772 C CG2    . ILE B 1 225 ? -12.233 29.287  -3.373  1.00 19.99  ? 225 ILE B CG2    1 
ATOM   10773 C CD1    . ILE B 1 225 ? -14.576 28.297  -5.097  1.00 15.60  ? 225 ILE B CD1    1 
ATOM   10774 H H      . ILE B 1 225 ? -11.175 29.342  -7.172  1.00 23.24  ? 225 ILE B H      1 
ATOM   10775 H HA     . ILE B 1 225 ? -11.780 31.218  -5.436  1.00 22.32  ? 225 ILE B HA     1 
ATOM   10776 H HB     . ILE B 1 225 ? -11.853 28.405  -5.201  1.00 19.93  ? 225 ILE B HB     1 
ATOM   10777 H HG12   . ILE B 1 225 ? -13.995 30.247  -5.148  1.00 18.46  ? 225 ILE B HG12   1 
ATOM   10778 H HG13   . ILE B 1 225 ? -13.567 29.441  -6.444  1.00 18.46  ? 225 ILE B HG13   1 
ATOM   10779 H HG21   . ILE B 1 225 ? -12.955 28.725  -3.055  1.00 23.99  ? 225 ILE B HG21   1 
ATOM   10780 H HG22   . ILE B 1 225 ? -11.389 28.951  -3.034  1.00 23.99  ? 225 ILE B HG22   1 
ATOM   10781 H HG23   . ILE B 1 225 ? -12.372 30.200  -3.075  1.00 23.99  ? 225 ILE B HG23   1 
ATOM   10782 H HD11   . ILE B 1 225 ? -15.348 28.332  -5.683  1.00 18.73  ? 225 ILE B HD11   1 
ATOM   10783 H HD12   . ILE B 1 225 ? -14.122 27.446  -5.199  1.00 18.73  ? 225 ILE B HD12   1 
ATOM   10784 H HD13   . ILE B 1 225 ? -14.854 28.415  -4.175  1.00 18.73  ? 225 ILE B HD13   1 
ATOM   10785 N N      . LYS B 1 226 ? -9.105  29.565  -4.864  1.00 15.89  ? 226 LYS B N      1 
ATOM   10786 C CA     . LYS B 1 226 ? -7.852  29.593  -4.126  1.00 15.72  ? 226 LYS B CA     1 
ATOM   10787 C C      . LYS B 1 226 ? -7.053  30.844  -4.443  1.00 19.35  ? 226 LYS B C      1 
ATOM   10788 O O      . LYS B 1 226 ? -6.444  31.453  -3.561  1.00 17.87  ? 226 LYS B O      1 
ATOM   10789 C CB     . LYS B 1 226 ? -7.013  28.355  -4.428  1.00 15.97  ? 226 LYS B CB     1 
ATOM   10790 C CG     . LYS B 1 226 ? -5.745  28.260  -3.583  1.00 16.23  ? 226 LYS B CG     1 
ATOM   10791 C CD     . LYS B 1 226 ? -5.069  26.914  -3.734  1.00 17.04  ? 226 LYS B CD     1 
ATOM   10792 C CE     . LYS B 1 226 ? -3.716  26.872  -3.040  1.00 18.71  ? 226 LYS B CE     1 
ATOM   10793 N NZ     . LYS B 1 226 ? -3.838  27.058  -1.558  1.00 19.61  ? 226 LYS B NZ     1 
ATOM   10794 H H      . LYS B 1 226 ? -9.182  28.905  -5.410  1.00 19.07  ? 226 LYS B H      1 
ATOM   10795 H HA     . LYS B 1 226 ? -8.047  29.597  -3.176  1.00 18.87  ? 226 LYS B HA     1 
ATOM   10796 H HB2    . LYS B 1 226 ? -7.546  27.563  -4.257  1.00 19.16  ? 226 LYS B HB2    1 
ATOM   10797 H HB3    . LYS B 1 226 ? -6.747  28.377  -5.361  1.00 19.16  ? 226 LYS B HB3    1 
ATOM   10798 H HG2    . LYS B 1 226 ? -5.120  28.945  -3.866  1.00 19.48  ? 226 LYS B HG2    1 
ATOM   10799 H HG3    . LYS B 1 226 ? -5.974  28.381  -2.648  1.00 19.48  ? 226 LYS B HG3    1 
ATOM   10800 H HD2    . LYS B 1 226 ? -5.632  26.229  -3.341  1.00 20.45  ? 226 LYS B HD2    1 
ATOM   10801 H HD3    . LYS B 1 226 ? -4.930  26.732  -4.677  1.00 20.45  ? 226 LYS B HD3    1 
ATOM   10802 H HE2    . LYS B 1 226 ? -3.301  26.011  -3.203  1.00 22.45  ? 226 LYS B HE2    1 
ATOM   10803 H HE3    . LYS B 1 226 ? -3.157  27.584  -3.389  1.00 22.45  ? 226 LYS B HE3    1 
ATOM   10804 H HZ1    . LYS B 1 226 ? -3.031  27.047  -1.183  1.00 23.53  ? 226 LYS B HZ1    1 
ATOM   10805 H HZ2    . LYS B 1 226 ? -4.229  27.838  -1.381  1.00 23.53  ? 226 LYS B HZ2    1 
ATOM   10806 H HZ3    . LYS B 1 226 ? -4.328  26.402  -1.209  1.00 23.53  ? 226 LYS B HZ3    1 
ATOM   10807 N N      . GLU B 1 227 ? -7.058  31.238  -5.706  1.00 16.92  ? 227 GLU B N      1 
ATOM   10808 C CA     . GLU B 1 227 ? -6.259  32.379  -6.129  1.00 18.94  ? 227 GLU B CA     1 
ATOM   10809 C C      . GLU B 1 227 ? -6.884  33.730  -5.778  1.00 20.25  ? 227 GLU B C      1 
ATOM   10810 O O      . GLU B 1 227 ? -6.158  34.698  -5.525  1.00 20.30  ? 227 GLU B O      1 
ATOM   10811 C CB     . GLU B 1 227 ? -6.031  32.332  -7.643  1.00 18.77  ? 227 GLU B CB     1 
ATOM   10812 C CG     . GLU B 1 227 ? -4.944  33.279  -8.138  1.00 20.19  ? 227 GLU B CG     1 
ATOM   10813 C CD     . GLU B 1 227 ? -4.861  33.319  -9.659  1.00 25.37  ? 227 GLU B CD     1 
ATOM   10814 O OE1    . GLU B 1 227 ? -5.917  33.491  -10.308 1.00 21.83  ? 227 GLU B OE1    1 
ATOM   10815 O OE2    . GLU B 1 227 ? -3.743  33.170  -10.202 1.00 26.61  ? 227 GLU B OE2    1 
ATOM   10816 H H      . GLU B 1 227 ? -7.511  30.866  -6.335  1.00 20.30  ? 227 GLU B H      1 
ATOM   10817 H HA     . GLU B 1 227 ? -5.391  32.332  -5.698  1.00 22.73  ? 227 GLU B HA     1 
ATOM   10818 H HB2    . GLU B 1 227 ? -5.772  31.431  -7.891  1.00 22.53  ? 227 GLU B HB2    1 
ATOM   10819 H HB3    . GLU B 1 227 ? -6.858  32.570  -8.090  1.00 22.53  ? 227 GLU B HB3    1 
ATOM   10820 H HG2    . GLU B 1 227 ? -5.135  34.177  -7.826  1.00 24.22  ? 227 GLU B HG2    1 
ATOM   10821 H HG3    . GLU B 1 227 ? -4.086  32.983  -7.797  1.00 24.22  ? 227 GLU B HG3    1 
ATOM   10822 N N      . GLN B 1 228 ? -8.214  33.807  -5.796  1.00 18.63  ? 228 GLN B N      1 
ATOM   10823 C CA     . GLN B 1 228 ? -8.893  35.109  -5.822  1.00 19.19  ? 228 GLN B CA     1 
ATOM   10824 C C      . GLN B 1 228 ? -9.966  35.362  -4.756  1.00 23.21  ? 228 GLN B C      1 
ATOM   10825 O O      . GLN B 1 228 ? -10.384 36.508  -4.589  1.00 21.22  ? 228 GLN B O      1 
ATOM   10826 C CB     . GLN B 1 228 ? -9.526  35.319  -7.204  1.00 22.56  ? 228 GLN B CB     1 
ATOM   10827 C CG     . GLN B 1 228 ? -8.493  35.353  -8.316  1.00 25.08  ? 228 GLN B CG     1 
ATOM   10828 C CD     . GLN B 1 228 ? -9.057  35.757  -9.665  1.00 27.22  ? 228 GLN B CD     1 
ATOM   10829 O OE1    . GLN B 1 228 ? -10.123 36.368  -9.762  1.00 27.14  ? 228 GLN B OE1    1 
ATOM   10830 N NE2    . GLN B 1 228 ? -8.332  35.420  -10.719 1.00 25.84  ? 228 GLN B NE2    1 
ATOM   10831 H H      . GLN B 1 228 ? -8.744  33.130  -5.794  1.00 22.36  ? 228 GLN B H      1 
ATOM   10832 H HA     . GLN B 1 228 ? -8.232  35.808  -5.712  1.00 23.02  ? 228 GLN B HA     1 
ATOM   10833 H HB2    . GLN B 1 228 ? -10.146 34.597  -7.387  1.00 27.07  ? 228 GLN B HB2    1 
ATOM   10834 H HB3    . GLN B 1 228 ? -9.997  36.167  -7.207  1.00 27.07  ? 228 GLN B HB3    1 
ATOM   10835 H HG2    . GLN B 1 228 ? -7.801  35.991  -8.081  1.00 30.09  ? 228 GLN B HG2    1 
ATOM   10836 H HG3    . GLN B 1 228 ? -8.106  34.469  -8.410  1.00 30.09  ? 228 GLN B HG3    1 
ATOM   10837 H HE21   . GLN B 1 228 ? -7.590  34.998  -10.613 1.00 31.01  ? 228 GLN B HE21   1 
ATOM   10838 H HE22   . GLN B 1 228 ? -8.602  35.623  -11.510 1.00 31.01  ? 228 GLN B HE22   1 
ATOM   10839 N N      . GLU B 1 229 ? -10.423 34.327  -4.051  1.00 20.23  ? 229 GLU B N      1 
ATOM   10840 C CA     . GLU B 1 229 ? -11.444 34.518  -3.021  1.00 21.89  ? 229 GLU B CA     1 
ATOM   10841 C C      . GLU B 1 229 ? -10.768 34.724  -1.673  1.00 26.78  ? 229 GLU B C      1 
ATOM   10842 O O      . GLU B 1 229 ? -9.980  33.891  -1.218  1.00 22.44  ? 229 GLU B O      1 
ATOM   10843 C CB     . GLU B 1 229 ? -12.418 33.339  -2.957  1.00 20.88  ? 229 GLU B CB     1 
ATOM   10844 C CG     . GLU B 1 229 ? -13.562 33.561  -1.965  1.00 22.93  ? 229 GLU B CG     1 
ATOM   10845 C CD     . GLU B 1 229 ? -14.799 32.710  -2.241  1.00 27.26  ? 229 GLU B CD     1 
ATOM   10846 O OE1    . GLU B 1 229 ? -14.719 31.790  -3.088  1.00 20.94  ? 229 GLU B OE1    1 
ATOM   10847 O OE2    . GLU B 1 229 ? -15.865 32.970  -1.613  1.00 21.06  ? 229 GLU B OE2    1 
ATOM   10848 H H      . GLU B 1 229 ? -10.162 33.513  -4.148  1.00 24.28  ? 229 GLU B H      1 
ATOM   10849 H HA     . GLU B 1 229 ? -11.963 35.312  -3.220  1.00 26.27  ? 229 GLU B HA     1 
ATOM   10850 H HB2    . GLU B 1 229 ? -12.803 33.206  -3.837  1.00 25.06  ? 229 GLU B HB2    1 
ATOM   10851 H HB3    . GLU B 1 229 ? -11.934 32.544  -2.683  1.00 25.06  ? 229 GLU B HB3    1 
ATOM   10852 H HG2    . GLU B 1 229 ? -13.248 33.345  -1.073  1.00 27.51  ? 229 GLU B HG2    1 
ATOM   10853 H HG3    . GLU B 1 229 ? -13.830 34.493  -2.002  1.00 27.51  ? 229 GLU B HG3    1 
ATOM   10854 N N      . GLU B 1 230 ? -11.076 35.855  -1.046  1.00 22.50  ? 230 GLU B N      1 
ATOM   10855 C CA     . GLU B 1 230 ? -10.437 36.230  0.204   1.00 29.16  ? 230 GLU B CA     1 
ATOM   10856 C C      . GLU B 1 230 ? -10.626 35.132  1.237   1.00 21.28  ? 230 GLU B C      1 
ATOM   10857 O O      . GLU B 1 230 ? -11.746 34.679  1.461   1.00 23.01  ? 230 GLU B O      1 
ATOM   10858 C CB     . GLU B 1 230 ? -11.013 37.548  0.727   1.00 42.63  ? 230 GLU B CB     1 
ATOM   10859 C CG     . GLU B 1 230 ? -10.113 38.257  1.716   1.00 62.96  ? 230 GLU B CG     1 
ATOM   10860 C CD     . GLU B 1 230 ? -8.868  38.818  1.057   1.00 90.50  ? 230 GLU B CD     1 
ATOM   10861 O OE1    . GLU B 1 230 ? -8.928  39.957  0.546   1.00 101.34 ? 230 GLU B OE1    1 
ATOM   10862 O OE2    . GLU B 1 230 ? -7.833  38.117  1.042   1.00 91.07  ? 230 GLU B OE2    1 
ATOM   10863 H H      . GLU B 1 230 ? -11.656 36.424  -1.328  1.00 27.00  ? 230 GLU B H      1 
ATOM   10864 H HA     . GLU B 1 230 ? -9.486  36.347  0.055   1.00 34.99  ? 230 GLU B HA     1 
ATOM   10865 H HB2    . GLU B 1 230 ? -11.158 38.145  -0.023  1.00 51.16  ? 230 GLU B HB2    1 
ATOM   10866 H HB3    . GLU B 1 230 ? -11.856 37.367  1.171   1.00 51.16  ? 230 GLU B HB3    1 
ATOM   10867 H HG2    . GLU B 1 230 ? -10.600 38.994  2.118   1.00 75.55  ? 230 GLU B HG2    1 
ATOM   10868 H HG3    . GLU B 1 230 ? -9.835  37.628  2.400   1.00 75.55  ? 230 GLU B HG3    1 
ATOM   10869 N N      . GLY B 1 231 ? -9.524  34.697  1.837   1.00 24.14  ? 231 GLY B N      1 
ATOM   10870 C CA     . GLY B 1 231 ? -9.561  33.698  2.892   1.00 26.67  ? 231 GLY B CA     1 
ATOM   10871 C C      . GLY B 1 231 ? -9.122  32.307  2.464   1.00 25.58  ? 231 GLY B C      1 
ATOM   10872 O O      . GLY B 1 231 ? -8.864  31.448  3.307   1.00 22.58  ? 231 GLY B O      1 
ATOM   10873 H H      . GLY B 1 231 ? -8.731  34.971  1.646   1.00 28.97  ? 231 GLY B H      1 
ATOM   10874 H HA2    . GLY B 1 231 ? -8.977  33.984  3.612   1.00 32.01  ? 231 GLY B HA2    1 
ATOM   10875 H HA3    . GLY B 1 231 ? -10.460 33.633  3.248   1.00 32.01  ? 231 GLY B HA3    1 
ATOM   10876 N N      . PHE B 1 232 ? -9.023  32.074  1.158   1.00 21.30  ? 232 PHE B N      1 
ATOM   10877 C CA     . PHE B 1 232 ? -8.805  30.718  0.658   1.00 22.33  ? 232 PHE B CA     1 
ATOM   10878 C C      . PHE B 1 232 ? -7.403  30.481  0.153   1.00 21.46  ? 232 PHE B C      1 
ATOM   10879 O O      . PHE B 1 232 ? -7.120  29.415  -0.359  1.00 19.53  ? 232 PHE B O      1 
ATOM   10880 C CB     . PHE B 1 232 ? -9.807  30.405  -0.450  1.00 18.91  ? 232 PHE B CB     1 
ATOM   10881 C CG     . PHE B 1 232 ? -11.151 30.020  0.065   1.00 21.52  ? 232 PHE B CG     1 
ATOM   10882 C CD1    . PHE B 1 232 ? -11.391 28.726  0.480   1.00 19.39  ? 232 PHE B CD1    1 
ATOM   10883 C CD2    . PHE B 1 232 ? -12.169 30.954  0.163   1.00 23.06  ? 232 PHE B CD2    1 
ATOM   10884 C CE1    . PHE B 1 232 ? -12.624 28.360  0.971   1.00 21.55  ? 232 PHE B CE1    1 
ATOM   10885 C CE2    . PHE B 1 232 ? -13.408 30.595  0.653   1.00 22.44  ? 232 PHE B CE2    1 
ATOM   10886 C CZ     . PHE B 1 232 ? -13.634 29.296  1.066   1.00 24.92  ? 232 PHE B CZ     1 
ATOM   10887 H H      . PHE B 1 232 ? -9.077  32.675  0.546   1.00 25.55  ? 232 PHE B H      1 
ATOM   10888 H HA     . PHE B 1 232 ? -8.966  30.082  1.371   1.00 26.80  ? 232 PHE B HA     1 
ATOM   10889 H HB2    . PHE B 1 232 ? -9.916  31.193  -1.005  1.00 22.69  ? 232 PHE B HB2    1 
ATOM   10890 H HB3    . PHE B 1 232 ? -9.475  29.668  -0.986  1.00 22.69  ? 232 PHE B HB3    1 
ATOM   10891 H HD1    . PHE B 1 232 ? -10.713 28.092  0.424   1.00 23.27  ? 232 PHE B HD1    1 
ATOM   10892 H HD2    . PHE B 1 232 ? -12.018 31.830  -0.109  1.00 27.67  ? 232 PHE B HD2    1 
ATOM   10893 H HE1    . PHE B 1 232 ? -12.774 27.484  1.245   1.00 25.87  ? 232 PHE B HE1    1 
ATOM   10894 H HE2    . PHE B 1 232 ? -14.087 31.228  0.713   1.00 26.93  ? 232 PHE B HE2    1 
ATOM   10895 H HZ     . PHE B 1 232 ? -14.469 29.049  1.392   1.00 29.91  ? 232 PHE B HZ     1 
ATOM   10896 N N      . GLU B 1 233 ? -6.514  31.457  0.326   1.00 21.32  ? 233 GLU B N      1 
ATOM   10897 C CA     . GLU B 1 233 ? -5.201  31.386  -0.312  1.00 23.71  ? 233 GLU B CA     1 
ATOM   10898 C C      . GLU B 1 233 ? -4.371  30.194  0.171   1.00 22.66  ? 233 GLU B C      1 
ATOM   10899 O O      . GLU B 1 233 ? -3.566  29.663  -0.591  1.00 21.67  ? 233 GLU B O      1 
ATOM   10900 C CB     . GLU B 1 233 ? -4.405  32.681  -0.100  1.00 32.91  ? 233 GLU B CB     1 
ATOM   10901 C CG     . GLU B 1 233 ? -4.689  33.423  1.192   1.00 40.27  ? 233 GLU B CG     1 
ATOM   10902 C CD     . GLU B 1 233 ? -5.833  34.416  1.043   1.00 43.43  ? 233 GLU B CD     1 
ATOM   10903 O OE1    . GLU B 1 233 ? -5.671  35.426  0.317   1.00 52.88  ? 233 GLU B OE1    1 
ATOM   10904 O OE2    . GLU B 1 233 ? -6.900  34.177  1.643   1.00 32.72  ? 233 GLU B OE2    1 
ATOM   10905 H H      . GLU B 1 233 ? -6.655  32.154  0.802   1.00 25.58  ? 233 GLU B H      1 
ATOM   10906 H HA     . GLU B 1 233 ? -5.331  31.279  -1.267  1.00 28.45  ? 233 GLU B HA     1 
ATOM   10907 H HB2    . GLU B 1 233 ? -3.460  32.464  -0.108  1.00 39.49  ? 233 GLU B HB2    1 
ATOM   10908 H HB3    . GLU B 1 233 ? -4.604  33.286  -0.832  1.00 39.49  ? 233 GLU B HB3    1 
ATOM   10909 H HG2    . GLU B 1 233 ? -4.928  32.785  1.883   1.00 48.32  ? 233 GLU B HG2    1 
ATOM   10910 H HG3    . GLU B 1 233 ? -3.896  33.916  1.455   1.00 48.32  ? 233 GLU B HG3    1 
ATOM   10911 N N      . ASP B 1 234 ? -4.560  29.782  1.427   1.00 21.62  ? 234 ASP B N      1 
ATOM   10912 C CA     . ASP B 1 234 ? -3.778  28.679  2.011   1.00 25.52  ? 234 ASP B CA     1 
ATOM   10913 C C      . ASP B 1 234 ? -4.609  27.409  2.206   1.00 25.01  ? 234 ASP B C      1 
ATOM   10914 O O      . ASP B 1 234 ? -4.231  26.522  2.976   1.00 23.15  ? 234 ASP B O      1 
ATOM   10915 C CB     . ASP B 1 234 ? -3.178  29.093  3.361   1.00 23.75  ? 234 ASP B CB     1 
ATOM   10916 C CG     . ASP B 1 234 ? -2.261  30.298  3.254   1.00 32.77  ? 234 ASP B CG     1 
ATOM   10917 O OD1    . ASP B 1 234 ? -1.523  30.416  2.251   1.00 29.40  ? 234 ASP B OD1    1 
ATOM   10918 O OD2    . ASP B 1 234 ? -2.274  31.128  4.185   1.00 30.76  ? 234 ASP B OD2    1 
ATOM   10919 H H      . ASP B 1 234 ? -5.136  30.124  1.966   1.00 25.94  ? 234 ASP B H      1 
ATOM   10920 H HA     . ASP B 1 234 ? -3.041  28.458  1.422   1.00 30.62  ? 234 ASP B HA     1 
ATOM   10921 H HB2    . ASP B 1 234 ? -3.898  29.317  3.971   1.00 28.50  ? 234 ASP B HB2    1 
ATOM   10922 H HB3    . ASP B 1 234 ? -2.658  28.356  3.717   1.00 28.50  ? 234 ASP B HB3    1 
ATOM   10923 N N      . VAL B 1 235 ? -5.744  27.329  1.520   1.00 19.62  ? 235 VAL B N      1 
ATOM   10924 C CA     . VAL B 1 235 ? -6.576  26.131  1.545   1.00 17.80  ? 235 VAL B CA     1 
ATOM   10925 C C      . VAL B 1 235 ? -6.242  25.313  0.300   1.00 21.27  ? 235 VAL B C      1 
ATOM   10926 O O      . VAL B 1 235 ? -6.067  25.875  -0.784  1.00 19.95  ? 235 VAL B O      1 
ATOM   10927 C CB     . VAL B 1 235 ? -8.072  26.471  1.580   1.00 17.63  ? 235 VAL B CB     1 
ATOM   10928 C CG1    . VAL B 1 235 ? -8.910  25.199  1.681   1.00 19.62  ? 235 VAL B CG1    1 
ATOM   10929 C CG2    . VAL B 1 235 ? -8.379  27.423  2.753   1.00 21.41  ? 235 VAL B CG2    1 
ATOM   10930 H H      . VAL B 1 235 ? -6.058  27.960  1.027   1.00 23.55  ? 235 VAL B H      1 
ATOM   10931 H HA     . VAL B 1 235 ? -6.370  25.597  2.328   1.00 21.36  ? 235 VAL B HA     1 
ATOM   10932 H HB     . VAL B 1 235 ? -8.312  26.923  0.756   1.00 21.16  ? 235 VAL B HB     1 
ATOM   10933 H HG11   . VAL B 1 235 ? -9.842  25.445  1.787   1.00 23.55  ? 235 VAL B HG11   1 
ATOM   10934 H HG12   . VAL B 1 235 ? -8.797  24.677  0.872   1.00 23.55  ? 235 VAL B HG12   1 
ATOM   10935 H HG13   . VAL B 1 235 ? -8.614  24.687  2.450   1.00 23.55  ? 235 VAL B HG13   1 
ATOM   10936 H HG21   . VAL B 1 235 ? -9.337  27.565  2.801   1.00 25.69  ? 235 VAL B HG21   1 
ATOM   10937 H HG22   . VAL B 1 235 ? -8.062  27.020  3.577   1.00 25.69  ? 235 VAL B HG22   1 
ATOM   10938 H HG23   . VAL B 1 235 ? -7.927  28.268  2.602   1.00 25.69  ? 235 VAL B HG23   1 
ATOM   10939 N N      . SER B 1 236 ? -6.142  23.999  0.454   1.00 19.48  ? 236 SER B N      1 
ATOM   10940 C CA     . SER B 1 236 ? -5.767  23.135  -0.668  1.00 18.66  ? 236 SER B CA     1 
ATOM   10941 C C      . SER B 1 236 ? -6.889  23.063  -1.698  1.00 17.31  ? 236 SER B C      1 
ATOM   10942 O O      . SER B 1 236 ? -8.068  23.234  -1.376  1.00 15.96  ? 236 SER B O      1 
ATOM   10943 C CB     . SER B 1 236 ? -5.424  21.726  -0.178  1.00 20.12  ? 236 SER B CB     1 
ATOM   10944 O OG     . SER B 1 236 ? -6.595  21.045  0.256   1.00 20.90  ? 236 SER B OG     1 
ATOM   10945 H H      . SER B 1 236 ? -6.284  23.581  1.192   1.00 23.37  ? 236 SER B H      1 
ATOM   10946 H HA     . SER B 1 236 ? -4.982  23.502  -1.103  1.00 22.39  ? 236 SER B HA     1 
ATOM   10947 H HB2    . SER B 1 236 ? -5.020  21.228  -0.906  1.00 24.14  ? 236 SER B HB2    1 
ATOM   10948 H HB3    . SER B 1 236 ? -4.803  21.792  0.564   1.00 24.14  ? 236 SER B HB3    1 
ATOM   10949 H HG     . SER B 1 236 ? -6.399  20.268  0.507   1.00 25.07  ? 236 SER B HG     1 
ATOM   10950 N N      . ILE B 1 237 ? -6.516  22.799  -2.947  1.00 16.62  ? 237 ILE B N      1 
ATOM   10951 C CA     . ILE B 1 237 ? -7.492  22.563  -3.992  1.00 19.57  ? 237 ILE B CA     1 
ATOM   10952 C C      . ILE B 1 237 ? -8.465  21.463  -3.574  1.00 14.53  ? 237 ILE B C      1 
ATOM   10953 O O      . ILE B 1 237 ? -9.671  21.580  -3.765  1.00 16.41  ? 237 ILE B O      1 
ATOM   10954 C CB     . ILE B 1 237 ? -6.794  22.170  -5.318  1.00 17.38  ? 237 ILE B CB     1 
ATOM   10955 C CG1    . ILE B 1 237 ? -5.925  23.326  -5.819  1.00 17.91  ? 237 ILE B CG1    1 
ATOM   10956 C CG2    . ILE B 1 237 ? -7.817  21.747  -6.380  1.00 17.86  ? 237 ILE B CG2    1 
ATOM   10957 C CD1    . ILE B 1 237 ? -6.719  24.576  -6.240  1.00 18.03  ? 237 ILE B CD1    1 
ATOM   10958 H H      . ILE B 1 237 ? -5.699  22.751  -3.210  1.00 19.94  ? 237 ILE B H      1 
ATOM   10959 H HA     . ILE B 1 237 ? -8.003  23.373  -4.141  1.00 23.49  ? 237 ILE B HA     1 
ATOM   10960 H HB     . ILE B 1 237 ? -6.214  21.413  -5.140  1.00 20.86  ? 237 ILE B HB     1 
ATOM   10961 H HG12   . ILE B 1 237 ? -5.313  23.588  -5.114  1.00 21.50  ? 237 ILE B HG12   1 
ATOM   10962 H HG13   . ILE B 1 237 ? -5.422  23.023  -6.591  1.00 21.50  ? 237 ILE B HG13   1 
ATOM   10963 H HG21   . ILE B 1 237 ? -7.391  21.769  -7.251  1.00 21.43  ? 237 ILE B HG21   1 
ATOM   10964 H HG22   . ILE B 1 237 ? -8.125  20.848  -6.186  1.00 21.43  ? 237 ILE B HG22   1 
ATOM   10965 H HG23   . ILE B 1 237 ? -8.564  22.366  -6.363  1.00 21.43  ? 237 ILE B HG23   1 
ATOM   10966 H HD11   . ILE B 1 237 ? -6.100  25.237  -6.587  1.00 21.63  ? 237 ILE B HD11   1 
ATOM   10967 H HD12   . ILE B 1 237 ? -7.358  24.332  -6.927  1.00 21.63  ? 237 ILE B HD12   1 
ATOM   10968 H HD13   . ILE B 1 237 ? -7.183  24.935  -5.468  1.00 21.63  ? 237 ILE B HD13   1 
ATOM   10969 N N      . LYS B 1 238 ? -7.935  20.389  -2.998  1.00 17.55  ? 238 LYS B N      1 
ATOM   10970 C CA     . LYS B 1 238 ? -8.760  19.247  -2.593  1.00 18.67  ? 238 LYS B CA     1 
ATOM   10971 C C      . LYS B 1 238 ? -9.830  19.662  -1.575  1.00 18.84  ? 238 LYS B C      1 
ATOM   10972 O O      . LYS B 1 238 ? -10.998 19.266  -1.676  1.00 17.62  ? 238 LYS B O      1 
ATOM   10973 C CB     . LYS B 1 238 ? -7.856  18.135  -2.027  1.00 21.27  ? 238 LYS B CB     1 
ATOM   10974 C CG     . LYS B 1 238 ? -8.574  17.000  -1.331  1.00 29.97  ? 238 LYS B CG     1 
ATOM   10975 C CD     . LYS B 1 238 ? -7.647  15.809  -1.071  1.00 39.14  ? 238 LYS B CD     1 
ATOM   10976 C CE     . LYS B 1 238 ? -6.453  16.171  -0.203  1.00 59.67  ? 238 LYS B CE     1 
ATOM   10977 N NZ     . LYS B 1 238 ? -5.624  14.975  0.149   1.00 61.24  ? 238 LYS B NZ     1 
ATOM   10978 H H      . LYS B 1 238 ? -7.097  20.293  -2.829  1.00 21.06  ? 238 LYS B H      1 
ATOM   10979 H HA     . LYS B 1 238 ? -9.213  18.894  -3.375  1.00 22.40  ? 238 LYS B HA     1 
ATOM   10980 H HB2    . LYS B 1 238 ? -7.347  17.752  -2.758  1.00 25.53  ? 238 LYS B HB2    1 
ATOM   10981 H HB3    . LYS B 1 238 ? -7.249  18.534  -1.384  1.00 25.53  ? 238 LYS B HB3    1 
ATOM   10982 H HG2    . LYS B 1 238 ? -8.923  17.309  -0.480  1.00 35.96  ? 238 LYS B HG2    1 
ATOM   10983 H HG3    . LYS B 1 238 ? -9.292  16.691  -1.900  1.00 35.96  ? 238 LYS B HG3    1 
ATOM   10984 H HD2    . LYS B 1 238 ? -8.147  15.112  -0.618  1.00 46.97  ? 238 LYS B HD2    1 
ATOM   10985 H HD3    . LYS B 1 238 ? -7.312  15.478  -1.919  1.00 46.97  ? 238 LYS B HD3    1 
ATOM   10986 H HE2    . LYS B 1 238 ? -5.887  16.796  -0.683  1.00 71.60  ? 238 LYS B HE2    1 
ATOM   10987 H HE3    . LYS B 1 238 ? -6.769  16.572  0.620   1.00 71.60  ? 238 LYS B HE3    1 
ATOM   10988 H HZ1    . LYS B 1 238 ? -4.935  15.221  0.656   1.00 73.49  ? 238 LYS B HZ1    1 
ATOM   10989 H HZ2    . LYS B 1 238 ? -6.117  14.385  0.597   1.00 73.49  ? 238 LYS B HZ2    1 
ATOM   10990 H HZ3    . LYS B 1 238 ? -5.315  14.591  -0.592  1.00 73.49  ? 238 LYS B HZ3    1 
ATOM   10991 N N      . ASP B 1 239 ? -9.434  20.459  -0.588  1.00 19.93  ? 239 ASP B N      1 
ATOM   10992 C CA     . ASP B 1 239 ? -10.374 20.929  0.428   1.00 19.98  ? 239 ASP B CA     1 
ATOM   10993 C C      . ASP B 1 239 ? -11.382 21.940  -0.142  1.00 17.30  ? 239 ASP B C      1 
ATOM   10994 O O      . ASP B 1 239 ? -12.532 21.988  0.284   1.00 17.06  ? 239 ASP B O      1 
ATOM   10995 C CB     . ASP B 1 239 ? -9.606  21.543  1.609   1.00 19.28  ? 239 ASP B CB     1 
ATOM   10996 C CG     . ASP B 1 239 ? -8.920  20.487  2.483   1.00 30.34  ? 239 ASP B CG     1 
ATOM   10997 O OD1    . ASP B 1 239 ? -9.330  19.306  2.441   1.00 24.37  ? 239 ASP B OD1    1 
ATOM   10998 O OD2    . ASP B 1 239 ? -7.975  20.841  3.222   1.00 25.66  ? 239 ASP B OD2    1 
ATOM   10999 H H      . ASP B 1 239 ? -8.629  20.742  -0.483  1.00 23.92  ? 239 ASP B H      1 
ATOM   11000 H HA     . ASP B 1 239 ? -10.881 20.172  0.759   1.00 23.98  ? 239 ASP B HA     1 
ATOM   11001 H HB2    . ASP B 1 239 ? -8.922  22.139  1.266   1.00 23.14  ? 239 ASP B HB2    1 
ATOM   11002 H HB3    . ASP B 1 239 ? -10.227 22.037  2.167   1.00 23.14  ? 239 ASP B HB3    1 
ATOM   11003 N N      . ILE B 1 240 ? -10.965 22.734  -1.118  1.00 17.06  ? 240 ILE B N      1 
ATOM   11004 C CA     . ILE B 1 240 ? -11.892 23.659  -1.771  1.00 16.43  ? 240 ILE B CA     1 
ATOM   11005 C C      . ILE B 1 240 ? -12.942 22.882  -2.569  1.00 19.06  ? 240 ILE B C      1 
ATOM   11006 O O      . ILE B 1 240 ? -14.144 23.117  -2.437  1.00 16.93  ? 240 ILE B O      1 
ATOM   11007 C CB     . ILE B 1 240 ? -11.129 24.649  -2.661  1.00 16.24  ? 240 ILE B CB     1 
ATOM   11008 C CG1    . ILE B 1 240 ? -10.321 25.603  -1.773  1.00 15.66  ? 240 ILE B CG1    1 
ATOM   11009 C CG2    . ILE B 1 240 ? -12.084 25.430  -3.582  1.00 18.26  ? 240 ILE B CG2    1 
ATOM   11010 C CD1    . ILE B 1 240 ? -9.298  26.449  -2.510  1.00 18.09  ? 240 ILE B CD1    1 
ATOM   11011 H H      . ILE B 1 240 ? -10.161 22.760  -1.421  1.00 20.47  ? 240 ILE B H      1 
ATOM   11012 H HA     . ILE B 1 240 ? -12.356 24.171  -1.090  1.00 19.72  ? 240 ILE B HA     1 
ATOM   11013 H HB     . ILE B 1 240 ? -10.510 24.148  -3.215  1.00 19.49  ? 240 ILE B HB     1 
ATOM   11014 H HG12   . ILE B 1 240 ? -10.937 26.208  -1.331  1.00 18.79  ? 240 ILE B HG12   1 
ATOM   11015 H HG13   . ILE B 1 240 ? -9.845  25.081  -1.109  1.00 18.79  ? 240 ILE B HG13   1 
ATOM   11016 H HG21   . ILE B 1 240 ? -11.615 26.193  -3.952  1.00 21.91  ? 240 ILE B HG21   1 
ATOM   11017 H HG22   . ILE B 1 240 ? -12.381 24.849  -4.300  1.00 21.91  ? 240 ILE B HG22   1 
ATOM   11018 H HG23   . ILE B 1 240 ? -12.845 25.732  -3.063  1.00 21.91  ? 240 ILE B HG23   1 
ATOM   11019 H HD11   . ILE B 1 240 ? -8.745  26.911  -1.861  1.00 21.70  ? 240 ILE B HD11   1 
ATOM   11020 H HD12   . ILE B 1 240 ? -8.748  25.870  -3.061  1.00 21.70  ? 240 ILE B HD12   1 
ATOM   11021 H HD13   . ILE B 1 240 ? -9.761  27.093  -3.068  1.00 21.70  ? 240 ILE B HD13   1 
ATOM   11022 N N      . VAL B 1 241 ? -12.496 21.923  -3.368  1.00 17.91  ? 241 VAL B N      1 
ATOM   11023 C CA     . VAL B 1 241 ? -13.416 21.086  -4.119  1.00 16.72  ? 241 VAL B CA     1 
ATOM   11024 C C      . VAL B 1 241 ? -14.420 20.390  -3.200  1.00 17.49  ? 241 VAL B C      1 
ATOM   11025 O O      . VAL B 1 241 ? -15.608 20.379  -3.482  1.00 17.24  ? 241 VAL B O      1 
ATOM   11026 C CB     . VAL B 1 241 ? -12.648 20.028  -4.959  1.00 17.45  ? 241 VAL B CB     1 
ATOM   11027 C CG1    . VAL B 1 241 ? -13.597 18.998  -5.567  1.00 21.71  ? 241 VAL B CG1    1 
ATOM   11028 C CG2    . VAL B 1 241 ? -11.857 20.705  -6.062  1.00 17.91  ? 241 VAL B CG2    1 
ATOM   11029 H H      . VAL B 1 241 ? -11.666 21.737  -3.492  1.00 21.49  ? 241 VAL B H      1 
ATOM   11030 H HA     . VAL B 1 241 ? -13.916 21.646  -4.733  1.00 20.06  ? 241 VAL B HA     1 
ATOM   11031 H HB     . VAL B 1 241 ? -12.023 19.559  -4.384  1.00 20.94  ? 241 VAL B HB     1 
ATOM   11032 H HG11   . VAL B 1 241 ? -13.140 18.538  -6.288  1.00 26.06  ? 241 VAL B HG11   1 
ATOM   11033 H HG12   . VAL B 1 241 ? -13.857 18.361  -4.883  1.00 26.06  ? 241 VAL B HG12   1 
ATOM   11034 H HG13   . VAL B 1 241 ? -14.380 19.455  -5.912  1.00 26.06  ? 241 VAL B HG13   1 
ATOM   11035 H HG21   . VAL B 1 241 ? -11.272 20.052  -6.476  1.00 21.49  ? 241 VAL B HG21   1 
ATOM   11036 H HG22   . VAL B 1 241 ? -12.475 21.060  -6.720  1.00 21.49  ? 241 VAL B HG22   1 
ATOM   11037 H HG23   . VAL B 1 241 ? -11.331 21.424  -5.680  1.00 21.49  ? 241 VAL B HG23   1 
ATOM   11038 N N      . HIS B 1 242 ? -13.947 19.818  -2.100  1.00 16.75  ? 242 HIS B N      1 
ATOM   11039 C CA     . HIS B 1 242 ? -14.826 19.081  -1.204  1.00 17.13  ? 242 HIS B CA     1 
ATOM   11040 C C      . HIS B 1 242 ? -15.865 20.042  -0.623  1.00 20.14  ? 242 HIS B C      1 
ATOM   11041 O O      . HIS B 1 242 ? -17.055 19.734  -0.585  1.00 20.73  ? 242 HIS B O      1 
ATOM   11042 C CB     . HIS B 1 242 ? -14.028 18.405  -0.085  1.00 20.73  ? 242 HIS B CB     1 
ATOM   11043 C CG     . HIS B 1 242 ? -14.805 17.376  0.678   1.00 25.65  ? 242 HIS B CG     1 
ATOM   11044 N ND1    . HIS B 1 242 ? -15.512 17.673  1.824   1.00 23.04  ? 242 HIS B ND1    1 
ATOM   11045 C CD2    . HIS B 1 242 ? -14.978 16.049  0.462   1.00 24.15  ? 242 HIS B CD2    1 
ATOM   11046 C CE1    . HIS B 1 242 ? -16.094 16.575  2.277   1.00 26.47  ? 242 HIS B CE1    1 
ATOM   11047 N NE2    . HIS B 1 242 ? -15.786 15.576  1.469   1.00 25.53  ? 242 HIS B NE2    1 
ATOM   11048 H H      . HIS B 1 242 ? -13.124 19.842  -1.851  1.00 20.10  ? 242 HIS B H      1 
ATOM   11049 H HA     . HIS B 1 242 ? -15.292 18.393  -1.705  1.00 20.56  ? 242 HIS B HA     1 
ATOM   11050 H HB2    . HIS B 1 242 ? -13.256 17.965  -0.474  1.00 24.88  ? 242 HIS B HB2    1 
ATOM   11051 H HB3    . HIS B 1 242 ? -13.737 19.083  0.544   1.00 24.88  ? 242 HIS B HB3    1 
ATOM   11052 H HD1    . HIS B 1 242 ? -15.570 18.452  2.185   1.00 27.65  ? 242 HIS B HD1    1 
ATOM   11053 H HD2    . HIS B 1 242 ? -14.622 15.553  -0.239  1.00 28.98  ? 242 HIS B HD2    1 
ATOM   11054 H HE1    . HIS B 1 242 ? -16.627 16.516  3.037   1.00 31.76  ? 242 HIS B HE1    1 
ATOM   11055 N N      . GLU B 1 243 ? -15.422 21.226  -0.213  1.00 18.83  ? 243 GLU B N      1 
ATOM   11056 C CA     . GLU B 1 243 ? -16.358 22.184  0.364   1.00 19.86  ? 243 GLU B CA     1 
ATOM   11057 C C      . GLU B 1 243 ? -17.376 22.673  -0.662  1.00 17.78  ? 243 GLU B C      1 
ATOM   11058 O O      . GLU B 1 243 ? -18.555 22.797  -0.335  1.00 21.30  ? 243 GLU B O      1 
ATOM   11059 C CB     . GLU B 1 243 ? -15.641 23.384  0.976   1.00 22.52  ? 243 GLU B CB     1 
ATOM   11060 C CG     . GLU B 1 243 ? -16.660 24.305  1.658   1.00 22.87  ? 243 GLU B CG     1 
ATOM   11061 C CD     . GLU B 1 243 ? -16.068 25.502  2.364   1.00 29.67  ? 243 GLU B CD     1 
ATOM   11062 O OE1    . GLU B 1 243 ? -14.827 25.663  2.404   1.00 23.55  ? 243 GLU B OE1    1 
ATOM   11063 O OE2    . GLU B 1 243 ? -16.883 26.301  2.871   1.00 29.21  ? 243 GLU B OE2    1 
ATOM   11064 H H      . GLU B 1 243 ? -14.606 21.494  -0.256  1.00 22.60  ? 243 GLU B H      1 
ATOM   11065 H HA     . GLU B 1 243 ? -16.849 21.744  1.076   1.00 23.84  ? 243 GLU B HA     1 
ATOM   11066 H HB2    . GLU B 1 243 ? -15.006 23.079  1.642   1.00 27.02  ? 243 GLU B HB2    1 
ATOM   11067 H HB3    . GLU B 1 243 ? -15.190 23.885  0.278   1.00 27.02  ? 243 GLU B HB3    1 
ATOM   11068 H HG2    . GLU B 1 243 ? -17.272 24.649  0.991   1.00 27.44  ? 243 GLU B HG2    1 
ATOM   11069 H HG3    . GLU B 1 243 ? -17.151 23.789  2.316   1.00 27.44  ? 243 GLU B HG3    1 
ATOM   11070 N N      . MET B 1 244 ? -16.929 22.954  -1.886  1.00 19.74  ? 244 MET B N      1 
ATOM   11071 C CA     . MET B 1 244 ? -17.835 23.373  -2.958  1.00 20.00  ? 244 MET B CA     1 
ATOM   11072 C C      . MET B 1 244 ? -19.034 22.436  -3.037  1.00 18.38  ? 244 MET B C      1 
ATOM   11073 O O      . MET B 1 244 ? -20.189 22.875  -3.019  1.00 19.89  ? 244 MET B O      1 
ATOM   11074 C CB     . MET B 1 244 ? -17.119 23.405  -4.321  1.00 18.67  ? 244 MET B CB     1 
ATOM   11075 C CG     . MET B 1 244 ? -16.153 24.566  -4.518  1.00 20.71  ? 244 MET B CG     1 
ATOM   11076 S SD     . MET B 1 244 ? -15.164 24.458  -6.041  1.00 21.94  ? 244 MET B SD     1 
ATOM   11077 C CE     . MET B 1 244 ? -16.413 24.004  -7.234  1.00 22.66  ? 244 MET B CE     1 
ATOM   11078 H H      . MET B 1 244 ? -16.103 22.910  -2.123  1.00 23.69  ? 244 MET B H      1 
ATOM   11079 H HA     . MET B 1 244 ? -18.151 24.270  -2.767  1.00 24.00  ? 244 MET B HA     1 
ATOM   11080 H HB2    . MET B 1 244 ? -16.614 22.583  -4.425  1.00 22.41  ? 244 MET B HB2    1 
ATOM   11081 H HB3    . MET B 1 244 ? -17.794 23.462  -5.015  1.00 22.41  ? 244 MET B HB3    1 
ATOM   11082 H HG2    . MET B 1 244 ? -16.665 25.389  -4.560  1.00 24.85  ? 244 MET B HG2    1 
ATOM   11083 H HG3    . MET B 1 244 ? -15.543 24.603  -3.767  1.00 24.85  ? 244 MET B HG3    1 
ATOM   11084 H HE1    . MET B 1 244 ? -16.031 24.057  -8.124  1.00 27.20  ? 244 MET B HE1    1 
ATOM   11085 H HE2    . MET B 1 244 ? -16.707 23.097  -7.054  1.00 27.20  ? 244 MET B HE2    1 
ATOM   11086 H HE3    . MET B 1 244 ? -17.161 24.617  -7.159  1.00 27.20  ? 244 MET B HE3    1 
ATOM   11087 N N      . PHE B 1 245 ? -18.766 21.138  -3.127  1.00 18.06  ? 245 PHE B N      1 
ATOM   11088 C CA     . PHE B 1 245 ? -19.844 20.182  -3.344  1.00 18.23  ? 245 PHE B CA     1 
ATOM   11089 C C      . PHE B 1 245 ? -20.660 19.926  -2.075  1.00 18.31  ? 245 PHE B C      1 
ATOM   11090 O O      . PHE B 1 245 ? -21.743 19.348  -2.141  1.00 21.96  ? 245 PHE B O      1 
ATOM   11091 C CB     . PHE B 1 245 ? -19.290 18.863  -3.883  1.00 21.75  ? 245 PHE B CB     1 
ATOM   11092 C CG     . PHE B 1 245 ? -18.855 18.944  -5.313  1.00 18.49  ? 245 PHE B CG     1 
ATOM   11093 C CD1    . PHE B 1 245 ? -19.788 19.138  -6.315  1.00 20.71  ? 245 PHE B CD1    1 
ATOM   11094 C CD2    . PHE B 1 245 ? -17.515 18.831  -5.656  1.00 18.46  ? 245 PHE B CD2    1 
ATOM   11095 C CE1    . PHE B 1 245 ? -19.395 19.209  -7.645  1.00 24.93  ? 245 PHE B CE1    1 
ATOM   11096 C CE2    . PHE B 1 245 ? -17.114 18.897  -6.984  1.00 20.04  ? 245 PHE B CE2    1 
ATOM   11097 C CZ     . PHE B 1 245 ? -18.053 19.090  -7.976  1.00 22.89  ? 245 PHE B CZ     1 
ATOM   11098 H H      . PHE B 1 245 ? -17.982 20.790  -3.067  1.00 21.68  ? 245 PHE B H      1 
ATOM   11099 H HA     . PHE B 1 245 ? -20.448 20.542  -4.012  1.00 21.87  ? 245 PHE B HA     1 
ATOM   11100 H HB2    . PHE B 1 245 ? -18.521 18.605  -3.352  1.00 26.09  ? 245 PHE B HB2    1 
ATOM   11101 H HB3    . PHE B 1 245 ? -19.979 18.183  -3.819  1.00 26.09  ? 245 PHE B HB3    1 
ATOM   11102 H HD1    . PHE B 1 245 ? -20.689 19.215  -6.096  1.00 24.85  ? 245 PHE B HD1    1 
ATOM   11103 H HD2    . PHE B 1 245 ? -16.880 18.698  -4.990  1.00 22.15  ? 245 PHE B HD2    1 
ATOM   11104 H HE1    . PHE B 1 245 ? -20.030 19.339  -8.312  1.00 29.91  ? 245 PHE B HE1    1 
ATOM   11105 H HE2    . PHE B 1 245 ? -16.214 18.820  -7.203  1.00 24.05  ? 245 PHE B HE2    1 
ATOM   11106 H HZ     . PHE B 1 245 ? -17.786 19.140  -8.865  1.00 27.46  ? 245 PHE B HZ     1 
ATOM   11107 N N      . SER B 1 246 ? -20.153 20.357  -0.927  1.00 19.86  ? 246 SER B N      1 
ATOM   11108 C CA     . SER B 1 246 ? -20.908 20.210  0.321   1.00 21.72  ? 246 SER B CA     1 
ATOM   11109 C C      . SER B 1 246 ? -22.183 21.061  0.286   1.00 24.24  ? 246 SER B C      1 
ATOM   11110 O O      . SER B 1 246 ? -23.091 20.840  1.085   1.00 25.45  ? 246 SER B O      1 
ATOM   11111 C CB     . SER B 1 246 ? -20.060 20.590  1.542   1.00 22.75  ? 246 SER B CB     1 
ATOM   11112 O OG     . SER B 1 246 ? -19.974 21.999  1.721   1.00 23.24  ? 246 SER B OG     1 
ATOM   11113 H H      . SER B 1 246 ? -19.385 20.733  -0.837  1.00 23.83  ? 246 SER B H      1 
ATOM   11114 H HA     . SER B 1 246 ? -21.172 19.282  0.420   1.00 26.07  ? 246 SER B HA     1 
ATOM   11115 H HB2    . SER B 1 246 ? -20.462 20.200  2.334   1.00 27.31  ? 246 SER B HB2    1 
ATOM   11116 H HB3    . SER B 1 246 ? -19.165 20.236  1.421   1.00 27.31  ? 246 SER B HB3    1 
ATOM   11117 H HG     . SER B 1 246 ? -19.646 22.356  1.036   1.00 27.89  ? 246 SER B HG     1 
ATOM   11118 N N      . TYR B 1 247 ? -22.251 22.018  -0.643  1.00 23.62  ? 247 TYR B N      1 
ATOM   11119 C CA     . TYR B 1 247 ? -23.416 22.901  -0.772  1.00 23.03  ? 247 TYR B CA     1 
ATOM   11120 C C      . TYR B 1 247 ? -24.369 22.461  -1.874  1.00 26.24  ? 247 TYR B C      1 
ATOM   11121 O O      . TYR B 1 247 ? -25.273 23.209  -2.263  1.00 27.01  ? 247 TYR B O      1 
ATOM   11122 C CB     . TYR B 1 247 ? -22.960 24.343  -1.029  1.00 23.70  ? 247 TYR B CB     1 
ATOM   11123 C CG     . TYR B 1 247 ? -22.045 24.852  0.051   1.00 21.80  ? 247 TYR B CG     1 
ATOM   11124 C CD1    . TYR B 1 247 ? -22.487 24.950  1.364   1.00 25.85  ? 247 TYR B CD1    1 
ATOM   11125 C CD2    . TYR B 1 247 ? -20.735 25.210  -0.229  1.00 21.57  ? 247 TYR B CD2    1 
ATOM   11126 C CE1    . TYR B 1 247 ? -21.655 25.399  2.361   1.00 26.12  ? 247 TYR B CE1    1 
ATOM   11127 C CE2    . TYR B 1 247 ? -19.895 25.659  0.757   1.00 23.53  ? 247 TYR B CE2    1 
ATOM   11128 C CZ     . TYR B 1 247 ? -20.359 25.751  2.058   1.00 24.25  ? 247 TYR B CZ     1 
ATOM   11129 O OH     . TYR B 1 247 ? -19.529 26.196  3.056   1.00 23.78  ? 247 TYR B OH     1 
ATOM   11130 H H      . TYR B 1 247 ? -21.631 22.182  -1.216  1.00 28.35  ? 247 TYR B H      1 
ATOM   11131 H HA     . TYR B 1 247 ? -23.912 22.898  0.061   1.00 27.63  ? 247 TYR B HA     1 
ATOM   11132 H HB2    . TYR B 1 247 ? -22.481 24.379  -1.872  1.00 28.45  ? 247 TYR B HB2    1 
ATOM   11133 H HB3    . TYR B 1 247 ? -23.737 24.922  -1.062  1.00 28.45  ? 247 TYR B HB3    1 
ATOM   11134 H HD1    . TYR B 1 247 ? -23.361 24.709  1.571   1.00 31.01  ? 247 TYR B HD1    1 
ATOM   11135 H HD2    . TYR B 1 247 ? -20.421 25.146  -1.102  1.00 25.88  ? 247 TYR B HD2    1 
ATOM   11136 H HE1    . TYR B 1 247 ? -21.964 25.461  3.236   1.00 31.34  ? 247 TYR B HE1    1 
ATOM   11137 H HE2    . TYR B 1 247 ? -19.019 25.898  0.554   1.00 28.23  ? 247 TYR B HE2    1 
ATOM   11138 H HH     . TYR B 1 247 ? -18.753 26.310  2.755   1.00 28.53  ? 247 TYR B HH     1 
ATOM   11139 N N      . ALA B 1 248 ? -24.160 21.246  -2.374  1.00 26.13  ? 248 ALA B N      1 
ATOM   11140 C CA     . ALA B 1 248 ? -24.975 20.693  -3.447  1.00 26.31  ? 248 ALA B CA     1 
ATOM   11141 C C      . ALA B 1 248 ? -25.673 19.411  -3.011  1.00 21.93  ? 248 ALA B C      1 
ATOM   11142 O O      . ALA B 1 248 ? -25.229 18.723  -2.098  1.00 22.92  ? 248 ALA B O      1 
ATOM   11143 C CB     . ALA B 1 248 ? -24.116 20.424  -4.668  1.00 25.87  ? 248 ALA B CB     1 
ATOM   11144 H H      . ALA B 1 248 ? -23.543 20.712  -2.104  1.00 31.36  ? 248 ALA B H      1 
ATOM   11145 H HA     . ALA B 1 248 ? -25.660 21.330  -3.702  1.00 31.58  ? 248 ALA B HA     1 
ATOM   11146 H HB1    . ALA B 1 248 ? -24.683 20.114  -5.392  1.00 31.04  ? 248 ALA B HB1    1 
ATOM   11147 H HB2    . ALA B 1 248 ? -23.668 21.244  -4.924  1.00 31.04  ? 248 ALA B HB2    1 
ATOM   11148 H HB3    . ALA B 1 248 ? -23.458 19.746  -4.447  1.00 31.04  ? 248 ALA B HB3    1 
ATOM   11149 N N      . ASP B 1 249 ? -26.763 19.090  -3.690  1.00 22.59  ? 249 ASP B N      1 
ATOM   11150 C CA     . ASP B 1 249 ? -27.476 17.843  -3.453  1.00 27.20  ? 249 ASP B CA     1 
ATOM   11151 C C      . ASP B 1 249 ? -26.990 16.742  -4.392  1.00 25.25  ? 249 ASP B C      1 
ATOM   11152 O O      . ASP B 1 249 ? -27.311 15.567  -4.211  1.00 23.72  ? 249 ASP B O      1 
ATOM   11153 C CB     . ASP B 1 249 ? -28.976 18.062  -3.619  1.00 28.17  ? 249 ASP B CB     1 
ATOM   11154 C CG     . ASP B 1 249 ? -29.524 19.012  -2.586  1.00 31.37  ? 249 ASP B CG     1 
ATOM   11155 O OD1    . ASP B 1 249 ? -29.535 18.627  -1.399  1.00 29.45  ? 249 ASP B OD1    1 
ATOM   11156 O OD2    . ASP B 1 249 ? -29.911 20.141  -2.954  1.00 27.37  ? 249 ASP B OD2    1 
ATOM   11157 H H      . ASP B 1 249 ? -27.115 19.582  -4.301  1.00 27.10  ? 249 ASP B H      1 
ATOM   11158 H HA     . ASP B 1 249 ? -27.321 17.549  -2.542  1.00 32.64  ? 249 ASP B HA     1 
ATOM   11159 H HB2    . ASP B 1 249 ? -29.148 18.437  -4.497  1.00 33.81  ? 249 ASP B HB2    1 
ATOM   11160 H HB3    . ASP B 1 249 ? -29.435 17.213  -3.522  1.00 33.81  ? 249 ASP B HB3    1 
ATOM   11161 N N      . GLY B 1 250 ? -26.204 17.134  -5.388  1.00 24.43  ? 250 GLY B N      1 
ATOM   11162 C CA     . GLY B 1 250 ? -25.701 16.204  -6.381  1.00 22.75  ? 250 GLY B CA     1 
ATOM   11163 C C      . GLY B 1 250 ? -25.008 16.966  -7.490  1.00 22.98  ? 250 GLY B C      1 
ATOM   11164 O O      . GLY B 1 250 ? -24.883 18.192  -7.434  1.00 21.07  ? 250 GLY B O      1 
ATOM   11165 H H      . GLY B 1 250 ? -25.945 17.944  -5.514  1.00 29.31  ? 250 GLY B H      1 
ATOM   11166 H HA2    . GLY B 1 250 ? -25.068 15.592  -5.974  1.00 27.30  ? 250 GLY B HA2    1 
ATOM   11167 H HA3    . GLY B 1 250 ? -26.435 15.695  -6.759  1.00 27.30  ? 250 GLY B HA3    1 
ATOM   11168 N N      . CYS B 1 251 ? -24.547 16.248  -8.506  1.00 22.01  ? 251 CYS B N      1 
ATOM   11169 C CA     . CYS B 1 251 ? -23.897 16.903  -9.624  1.00 22.50  ? 251 CYS B CA     1 
ATOM   11170 C C      . CYS B 1 251 ? -23.890 16.017  -10.852 1.00 24.37  ? 251 CYS B C      1 
ATOM   11171 O O      . CYS B 1 251 ? -24.058 14.802  -10.771 1.00 23.17  ? 251 CYS B O      1 
ATOM   11172 C CB     . CYS B 1 251 ? -22.461 17.293  -9.267  1.00 21.50  ? 251 CYS B CB     1 
ATOM   11173 S SG     . CYS B 1 251 ? -21.305 15.895  -9.299  1.00 28.44  ? 251 CYS B SG     1 
ATOM   11174 H H      . CYS B 1 251 ? -24.598 15.392  -8.570  1.00 26.42  ? 251 CYS B H      1 
ATOM   11175 H HA     . CYS B 1 251 ? -24.387 17.710  -9.841  1.00 26.99  ? 251 CYS B HA     1 
ATOM   11176 H HB2    . CYS B 1 251 ? -22.148 17.953  -9.905  1.00 25.80  ? 251 CYS B HB2    1 
ATOM   11177 H HB3    . CYS B 1 251 ? -22.450 17.668  -8.373  1.00 25.80  ? 251 CYS B HB3    1 
ATOM   11178 H HG     . CYS B 1 251 ? -21.477 15.218  -8.327  1.00 34.12  ? 251 CYS B HG     1 
ATOM   11179 N N      . THR B 1 252 ? -23.741 16.653  -11.999 1.00 21.70  ? 252 THR B N      1 
ATOM   11180 C CA     . THR B 1 252 ? -23.423 15.957  -13.226 1.00 22.56  ? 252 THR B CA     1 
ATOM   11181 C C      . THR B 1 252 ? -21.981 16.323  -13.551 1.00 23.21  ? 252 THR B C      1 
ATOM   11182 O O      . THR B 1 252 ? -21.601 17.490  -13.459 1.00 24.86  ? 252 THR B O      1 
ATOM   11183 C CB     . THR B 1 252 ? -24.378 16.345  -14.352 1.00 26.98  ? 252 THR B CB     1 
ATOM   11184 O OG1    . THR B 1 252 ? -24.349 17.765  -14.534 1.00 25.24  ? 252 THR B OG1    1 
ATOM   11185 C CG2    . THR B 1 252 ? -25.796 15.921  -13.999 1.00 24.71  ? 252 THR B CG2    1 
ATOM   11186 H H      . THR B 1 252 ? -23.821 17.504  -12.093 1.00 26.05  ? 252 THR B H      1 
ATOM   11187 H HA     . THR B 1 252 ? -23.475 14.998  -13.097 1.00 27.08  ? 252 THR B HA     1 
ATOM   11188 H HB     . THR B 1 252 ? -24.115 15.903  -15.174 1.00 32.38  ? 252 THR B HB     1 
ATOM   11189 H HG1    . THR B 1 252 ? -23.578 18.011  -14.759 1.00 30.29  ? 252 THR B HG1    1 
ATOM   11190 H HG21   . THR B 1 252 ? -26.399 16.143  -14.726 1.00 29.66  ? 252 THR B HG21   1 
ATOM   11191 H HG22   . THR B 1 252 ? -25.827 14.964  -13.845 1.00 29.66  ? 252 THR B HG22   1 
ATOM   11192 H HG23   . THR B 1 252 ? -26.089 16.379  -13.196 1.00 29.66  ? 252 THR B HG23   1 
ATOM   11193 N N      . MET B 1 253 ? -21.174 15.331  -13.907 1.00 19.93  ? 253 MET B N      1 
ATOM   11194 C CA     . MET B 1 253 ? -19.762 15.568  -14.168 1.00 19.12  ? 253 MET B CA     1 
ATOM   11195 C C      . MET B 1 253 ? -19.361 15.040  -15.534 1.00 20.37  ? 253 MET B C      1 
ATOM   11196 O O      . MET B 1 253 ? -19.758 13.950  -15.930 1.00 18.78  ? 253 MET B O      1 
ATOM   11197 C CB     . MET B 1 253 ? -18.886 14.906  -13.106 1.00 19.14  ? 253 MET B CB     1 
ATOM   11198 C CG     . MET B 1 253 ? -17.393 15.210  -13.288 1.00 24.16  ? 253 MET B CG     1 
ATOM   11199 S SD     . MET B 1 253 ? -17.092 16.981  -13.190 1.00 26.21  ? 253 MET B SD     1 
ATOM   11200 C CE     . MET B 1 253 ? -15.321 17.040  -13.464 1.00 31.01  ? 253 MET B CE     1 
ATOM   11201 H H      . MET B 1 253 ? -21.419 14.513  -14.004 1.00 23.92  ? 253 MET B H      1 
ATOM   11202 H HA     . MET B 1 253 ? -19.584 16.519  -14.149 1.00 22.94  ? 253 MET B HA     1 
ATOM   11203 H HB2    . MET B 1 253 ? -19.153 15.229  -12.231 1.00 22.96  ? 253 MET B HB2    1 
ATOM   11204 H HB3    . MET B 1 253 ? -19.004 13.944  -13.155 1.00 22.96  ? 253 MET B HB3    1 
ATOM   11205 H HG2    . MET B 1 253 ? -16.888 14.780  -12.582 1.00 28.99  ? 253 MET B HG2    1 
ATOM   11206 H HG3    . MET B 1 253 ? -17.095 14.894  -14.155 1.00 28.99  ? 253 MET B HG3    1 
ATOM   11207 H HE1    . MET B 1 253 ? -15.029 17.965  -13.443 1.00 37.22  ? 253 MET B HE1    1 
ATOM   11208 H HE2    . MET B 1 253 ? -14.877 16.537  -12.764 1.00 37.22  ? 253 MET B HE2    1 
ATOM   11209 H HE3    . MET B 1 253 ? -15.122 16.650  -14.329 1.00 37.22  ? 253 MET B HE3    1 
ATOM   11210 N N      . SER B 1 254 ? -18.566 15.829  -16.241 1.00 19.51  ? 254 SER B N      1 
ATOM   11211 C CA     . SER B 1 254 ? -17.888 15.351  -17.434 1.00 19.89  ? 254 SER B CA     1 
ATOM   11212 C C      . SER B 1 254 ? -16.438 15.102  -17.094 1.00 20.49  ? 254 SER B C      1 
ATOM   11213 O O      . SER B 1 254 ? -15.682 16.038  -16.826 1.00 19.54  ? 254 SER B O      1 
ATOM   11214 C CB     . SER B 1 254 ? -17.990 16.349  -18.575 1.00 21.92  ? 254 SER B CB     1 
ATOM   11215 O OG     . SER B 1 254 ? -17.208 15.899  -19.664 1.00 20.68  ? 254 SER B OG     1 
ATOM   11216 H H      . SER B 1 254 ? -18.402 16.651  -16.049 1.00 23.42  ? 254 SER B H      1 
ATOM   11217 H HA     . SER B 1 254 ? -18.279 14.515  -17.731 1.00 23.87  ? 254 SER B HA     1 
ATOM   11218 H HB2    . SER B 1 254 ? -18.916 16.423  -18.854 1.00 26.30  ? 254 SER B HB2    1 
ATOM   11219 H HB3    . SER B 1 254 ? -17.659 17.211  -18.277 1.00 26.30  ? 254 SER B HB3    1 
ATOM   11220 H HG     . SER B 1 254 ? -17.259 16.446  -20.300 1.00 24.81  ? 254 SER B HG     1 
ATOM   11221 N N      . GLY B 1 255 ? -16.045 13.837  -17.091 1.00 17.57  ? 255 GLY B N      1 
ATOM   11222 C CA     . GLY B 1 255 ? -14.658 13.495  -16.852 1.00 18.68  ? 255 GLY B CA     1 
ATOM   11223 C C      . GLY B 1 255 ? -13.779 14.013  -17.972 1.00 18.28  ? 255 GLY B C      1 
ATOM   11224 O O      . GLY B 1 255 ? -12.604 14.329  -17.761 1.00 18.11  ? 255 GLY B O      1 
ATOM   11225 H H      . GLY B 1 255 ? -16.561 13.162  -17.224 1.00 21.08  ? 255 GLY B H      1 
ATOM   11226 H HA2    . GLY B 1 255 ? -14.372 13.895  -16.017 1.00 22.41  ? 255 GLY B HA2    1 
ATOM   11227 H HA3    . GLY B 1 255 ? -14.559 12.532  -16.792 1.00 22.41  ? 255 GLY B HA3    1 
ATOM   11228 N N      . LYS B 1 256 ? -14.373 14.125  -19.161 1.00 16.72  ? 256 LYS B N      1 
ATOM   11229 C CA     . LYS B 1 256 ? -13.694 14.632  -20.355 1.00 19.27  ? 256 LYS B CA     1 
ATOM   11230 C C      . LYS B 1 256 ? -13.130 16.026  -20.173 1.00 17.25  ? 256 LYS B C      1 
ATOM   11231 O O      . LYS B 1 256 ? -12.294 16.447  -20.969 1.00 18.23  ? 256 LYS B O      1 
ATOM   11232 C CB     . LYS B 1 256 ? -14.652 14.649  -21.548 1.00 18.37  ? 256 LYS B CB     1 
ATOM   11233 C CG     . LYS B 1 256 ? -15.217 13.296  -21.887 1.00 19.67  ? 256 LYS B CG     1 
ATOM   11234 C CD     . LYS B 1 256 ? -16.260 13.392  -22.982 1.00 18.84  ? 256 LYS B CD     1 
ATOM   11235 C CE     . LYS B 1 256 ? -15.631 13.651  -24.340 1.00 22.30  ? 256 LYS B CE     1 
ATOM   11236 N NZ     . LYS B 1 256 ? -16.664 13.646  -25.405 1.00 21.01  ? 256 LYS B NZ     1 
ATOM   11237 H H      . LYS B 1 256 ? -15.192 13.908  -19.306 1.00 20.06  ? 256 LYS B H      1 
ATOM   11238 H HA     . LYS B 1 256 ? -12.958 14.039  -20.572 1.00 23.13  ? 256 LYS B HA     1 
ATOM   11239 H HB2    . LYS B 1 256 ? -15.394 15.240  -21.346 1.00 22.04  ? 256 LYS B HB2    1 
ATOM   11240 H HB3    . LYS B 1 256 ? -14.175 14.975  -22.326 1.00 22.04  ? 256 LYS B HB3    1 
ATOM   11241 H HG2    . LYS B 1 256 ? -14.501 12.721  -22.198 1.00 23.61  ? 256 LYS B HG2    1 
ATOM   11242 H HG3    . LYS B 1 256 ? -15.637 12.914  -21.101 1.00 23.61  ? 256 LYS B HG3    1 
ATOM   11243 H HD2    . LYS B 1 256 ? -16.750 12.556  -23.030 1.00 22.61  ? 256 LYS B HD2    1 
ATOM   11244 H HD3    . LYS B 1 256 ? -16.865 14.124  -22.784 1.00 22.61  ? 256 LYS B HD3    1 
ATOM   11245 H HE2    . LYS B 1 256 ? -15.200 14.520  -24.336 1.00 26.76  ? 256 LYS B HE2    1 
ATOM   11246 H HE3    . LYS B 1 256 ? -14.986 12.953  -24.535 1.00 26.76  ? 256 LYS B HE3    1 
ATOM   11247 H HZ1    . LYS B 1 256 ? -17.073 12.856  -25.428 1.00 25.21  ? 256 LYS B HZ1    1 
ATOM   11248 H HZ2    . LYS B 1 256 ? -17.268 14.280  -25.246 1.00 25.21  ? 256 LYS B HZ2    1 
ATOM   11249 H HZ3    . LYS B 1 256 ? -16.286 13.798  -26.196 1.00 25.21  ? 256 LYS B HZ3    1 
HETATM 11250 N N1     . LLP B 1 257 ? -22.102 21.360  -19.270 1.00 29.17  ? 257 LLP B N1     1 
HETATM 11251 C C2     . LLP B 1 257 ? -20.983 22.071  -19.399 1.00 30.56  ? 257 LLP B C2     1 
HETATM 11252 C "C2'"  . LLP B 1 257 ? -20.870 23.459  -18.693 1.00 37.29  ? 257 LLP B "C2'"  1 
HETATM 11253 C C3     . LLP B 1 257 ? -19.908 21.556  -20.180 1.00 30.45  ? 257 LLP B C3     1 
HETATM 11254 O O3     . LLP B 1 257 ? -18.730 22.306  -20.317 1.00 36.24  ? 257 LLP B O3     1 
HETATM 11255 C C4     . LLP B 1 257 ? -20.013 20.321  -20.798 1.00 24.66  ? 257 LLP B C4     1 
HETATM 11256 C "C4'"  . LLP B 1 257 ? -18.778 19.775  -21.675 1.00 25.78  ? 257 LLP B "C4'"  1 
HETATM 11257 C C5     . LLP B 1 257 ? -21.160 19.600  -20.670 1.00 26.95  ? 257 LLP B C5     1 
HETATM 11258 C C6     . LLP B 1 257 ? -22.212 20.115  -19.905 1.00 29.33  ? 257 LLP B C6     1 
HETATM 11259 C "C5'"  . LLP B 1 257 ? -21.389 18.211  -21.347 1.00 24.22  ? 257 LLP B "C5'"  1 
HETATM 11260 O OP4    . LLP B 1 257 ? -20.428 17.259  -20.959 1.00 20.63  ? 257 LLP B OP4    1 
HETATM 11261 P P      . LLP B 1 257 ? -20.027 16.157  -21.978 1.00 20.21  ? 257 LLP B P      1 
HETATM 11262 O OP1    . LLP B 1 257 ? -19.067 15.202  -21.254 1.00 21.80  ? 257 LLP B OP1    1 
HETATM 11263 O OP2    . LLP B 1 257 ? -19.393 16.814  -23.150 1.00 21.94  ? 257 LLP B OP2    1 
HETATM 11264 O OP3    . LLP B 1 257 ? -21.249 15.401  -22.399 1.00 23.36  ? 257 LLP B OP3    1 
HETATM 11265 N N      . LLP B 1 257 ? -13.595 16.746  -19.150 1.00 14.93  ? 257 LLP B N      1 
HETATM 11266 C CA     . LLP B 1 257 ? -13.058 18.083  -18.842 1.00 19.68  ? 257 LLP B CA     1 
HETATM 11267 C CB     . LLP B 1 257 ? -14.185 19.065  -18.564 1.00 17.93  ? 257 LLP B CB     1 
HETATM 11268 C CG     . LLP B 1 257 ? -14.687 19.682  -19.885 1.00 24.33  ? 257 LLP B CG     1 
HETATM 11269 C CD     . LLP B 1 257 ? -15.711 18.764  -20.568 1.00 25.60  ? 257 LLP B CD     1 
HETATM 11270 C CE     . LLP B 1 257 ? -16.407 19.536  -21.710 1.00 24.15  ? 257 LLP B CE     1 
HETATM 11271 N NZ     . LLP B 1 257 ? -17.548 20.319  -21.197 1.00 26.05  ? 257 LLP B NZ     1 
HETATM 11272 C C      . LLP B 1 257 ? -12.082 17.919  -17.713 1.00 18.81  ? 257 LLP B C      1 
HETATM 11273 O O      . LLP B 1 257 ? -10.981 17.453  -17.960 1.00 17.32  ? 257 LLP B O      1 
HETATM 11274 H "H2'1" . LLP B 1 257 ? -20.221 23.404  -17.974 1.00 44.75  ? 257 LLP B "H2'1" 1 
HETATM 11275 H "H2'2" . LLP B 1 257 ? -21.733 23.712  -18.329 1.00 44.75  ? 257 LLP B "H2'2" 1 
HETATM 11276 H "H2'3" . LLP B 1 257 ? -20.583 24.125  -19.338 1.00 44.75  ? 257 LLP B "H2'3" 1 
HETATM 11277 H HO3    . LLP B 1 257 ? -18.712 22.670  -21.085 1.00 43.49  ? 257 LLP B HO3    1 
HETATM 11278 H "H4'1" . LLP B 1 257 ? -18.903 20.040  -22.599 1.00 30.94  ? 257 LLP B "H4'1" 1 
HETATM 11279 H H6     . LLP B 1 257 ? -22.985 19.624  -19.824 1.00 35.20  ? 257 LLP B H6     1 
HETATM 11280 H "H5'1" . LLP B 1 257 ? -21.351 18.323  -22.310 1.00 29.07  ? 257 LLP B "H5'1" 1 
HETATM 11281 H "H5'2" . LLP B 1 257 ? -22.269 17.883  -21.104 1.00 29.07  ? 257 LLP B "H5'2" 1 
HETATM 11282 H HA     . LLP B 1 257 ? -12.564 18.407  -19.610 1.00 23.62  ? 257 LLP B HA     1 
HETATM 11283 H HB2    . LLP B 1 257 ? -13.863 19.772  -17.984 1.00 21.52  ? 257 LLP B HB2    1 
HETATM 11284 H HB3    . LLP B 1 257 ? -14.916 18.598  -18.130 1.00 21.52  ? 257 LLP B HB3    1 
HETATM 11285 H HG2    . LLP B 1 257 ? -13.938 19.827  -20.484 1.00 29.19  ? 257 LLP B HG2    1 
HETATM 11286 H HG3    . LLP B 1 257 ? -15.108 20.535  -19.694 1.00 29.19  ? 257 LLP B HG3    1 
HETATM 11287 H HD2    . LLP B 1 257 ? -16.373 18.477  -19.920 1.00 30.72  ? 257 LLP B HD2    1 
HETATM 11288 H HD3    . LLP B 1 257 ? -15.257 17.988  -20.932 1.00 30.72  ? 257 LLP B HD3    1 
HETATM 11289 H HE2    . LLP B 1 257 ? -16.719 18.907  -22.379 1.00 28.98  ? 257 LLP B HE2    1 
HETATM 11290 H HE3    . LLP B 1 257 ? -15.767 20.142  -22.116 1.00 28.98  ? 257 LLP B HE3    1 
ATOM   11291 N N      . ASP B 1 258 ? -12.452 18.244  -16.475 1.00 17.43  ? 258 ASP B N      1 
ATOM   11292 C CA     . ASP B 1 258 ? -11.429 18.314  -15.417 1.00 18.62  ? 258 ASP B CA     1 
ATOM   11293 C C      . ASP B 1 258 ? -10.945 16.981  -14.798 1.00 21.17  ? 258 ASP B C      1 
ATOM   11294 O O      . ASP B 1 258 ? -10.060 17.017  -13.950 1.00 22.62  ? 258 ASP B O      1 
ATOM   11295 C CB     . ASP B 1 258 ? -11.916 19.240  -14.286 1.00 18.78  ? 258 ASP B CB     1 
ATOM   11296 C CG     . ASP B 1 258 ? -11.411 20.675  -14.443 1.00 20.45  ? 258 ASP B CG     1 
ATOM   11297 O OD1    . ASP B 1 258 ? -10.501 20.918  -15.267 1.00 24.84  ? 258 ASP B OD1    1 
ATOM   11298 O OD2    . ASP B 1 258 ? -11.910 21.569  -13.731 1.00 20.67  ? 258 ASP B OD2    1 
ATOM   11299 H H      . ASP B 1 258 ? -13.255 18.422  -16.223 1.00 20.92  ? 258 ASP B H      1 
ATOM   11300 H HA     . ASP B 1 258 ? -10.639 18.709  -15.811 1.00 22.35  ? 258 ASP B HA     1 
ATOM   11301 H HB2    . ASP B 1 258 ? -12.886 19.262  -14.292 1.00 22.53  ? 258 ASP B HB2    1 
ATOM   11302 H HB3    . ASP B 1 258 ? -11.598 18.903  -13.434 1.00 22.53  ? 258 ASP B HB3    1 
ATOM   11303 N N      . CYS B 1 259 ? -11.451 15.817  -15.227 1.00 17.87  ? 259 CYS B N      1 
ATOM   11304 C CA     . CYS B 1 259 ? -10.890 14.541  -14.747 1.00 20.36  ? 259 CYS B CA     1 
ATOM   11305 C C      . CYS B 1 259 ? -9.776  14.000  -15.662 1.00 18.34  ? 259 CYS B C      1 
ATOM   11306 O O      . CYS B 1 259 ? -9.325  12.868  -15.496 1.00 16.47  ? 259 CYS B O      1 
ATOM   11307 C CB     . CYS B 1 259 ? -11.966 13.467  -14.605 1.00 20.60  ? 259 CYS B CB     1 
ATOM   11308 S SG     . CYS B 1 259 ? -13.236 13.851  -13.388 1.00 23.61  ? 259 CYS B SG     1 
ATOM   11309 H H      . CYS B 1 259 ? -12.103 15.737  -15.782 1.00 21.45  ? 259 CYS B H      1 
ATOM   11310 H HA     . CYS B 1 259 ? -10.505 14.672  -13.867 1.00 24.43  ? 259 CYS B HA     1 
ATOM   11311 H HB2    . CYS B 1 259 ? -12.392 13.335  -15.463 1.00 24.72  ? 259 CYS B HB2    1 
ATOM   11312 H HB3    . CYS B 1 259 ? -11.542 12.641  -14.325 1.00 24.72  ? 259 CYS B HB3    1 
ATOM   11313 H HG     . CYS B 1 259 ? -14.028 12.951  -13.353 1.00 28.33  ? 259 CYS B HG     1 
ATOM   11314 N N      . LEU B 1 260 ? -9.342  14.807  -16.623 1.00 15.07  ? 260 LEU B N      1 
ATOM   11315 C CA     . LEU B 1 260 ? -8.131  14.515  -17.390 1.00 15.53  ? 260 LEU B CA     1 
ATOM   11316 C C      . LEU B 1 260 ? -8.228  13.187  -18.155 1.00 16.31  ? 260 LEU B C      1 
ATOM   11317 O O      . LEU B 1 260 ? -7.280  12.404  -18.194 1.00 16.57  ? 260 LEU B O      1 
ATOM   11318 C CB     . LEU B 1 260 ? -6.909  14.512  -16.449 1.00 15.82  ? 260 LEU B CB     1 
ATOM   11319 C CG     . LEU B 1 260 ? -6.518  15.891  -15.899 1.00 16.00  ? 260 LEU B CG     1 
ATOM   11320 C CD1    . LEU B 1 260 ? -5.611  15.793  -14.678 1.00 14.56  ? 260 LEU B CD1    1 
ATOM   11321 C CD2    . LEU B 1 260 ? -5.807  16.668  -16.996 1.00 16.14  ? 260 LEU B CD2    1 
ATOM   11322 H H      . LEU B 1 260 ? -9.732  15.537  -16.856 1.00 18.08  ? 260 LEU B H      1 
ATOM   11323 H HA     . LEU B 1 260 ? -8.000  15.220  -18.043 1.00 18.63  ? 260 LEU B HA     1 
ATOM   11324 H HB2    . LEU B 1 260 ? -7.090  13.935  -15.692 1.00 18.98  ? 260 LEU B HB2    1 
ATOM   11325 H HB3    . LEU B 1 260 ? -6.142  14.173  -16.936 1.00 18.98  ? 260 LEU B HB3    1 
ATOM   11326 H HG     . LEU B 1 260 ? -7.319  16.378  -15.648 1.00 19.20  ? 260 LEU B HG     1 
ATOM   11327 H HD11   . LEU B 1 260 ? -5.398  16.688  -14.371 1.00 17.47  ? 260 LEU B HD11   1 
ATOM   11328 H HD12   . LEU B 1 260 ? -6.074  15.305  -13.980 1.00 17.47  ? 260 LEU B HD12   1 
ATOM   11329 H HD13   . LEU B 1 260 ? -4.798  15.325  -14.926 1.00 17.47  ? 260 LEU B HD13   1 
ATOM   11330 H HD21   . LEU B 1 260 ? -5.438  17.481  -16.618 1.00 19.37  ? 260 LEU B HD21   1 
ATOM   11331 H HD22   . LEU B 1 260 ? -5.093  16.121  -17.360 1.00 19.37  ? 260 LEU B HD22   1 
ATOM   11332 H HD23   . LEU B 1 260 ? -6.445  16.886  -17.694 1.00 19.37  ? 260 LEU B HD23   1 
ATOM   11333 N N      . VAL B 1 261 ? -9.390  12.940  -18.757 1.00 16.08  ? 261 VAL B N      1 
ATOM   11334 C CA     . VAL B 1 261 ? -9.589  11.743  -19.563 1.00 15.37  ? 261 VAL B CA     1 
ATOM   11335 C C      . VAL B 1 261 ? -10.193 12.086  -20.921 1.00 16.18  ? 261 VAL B C      1 
ATOM   11336 O O      . VAL B 1 261 ? -10.535 13.252  -21.204 1.00 15.23  ? 261 VAL B O      1 
ATOM   11337 C CB     . VAL B 1 261 ? -10.475 10.713  -18.816 1.00 13.82  ? 261 VAL B CB     1 
ATOM   11338 C CG1    . VAL B 1 261 ? -9.693  10.103  -17.655 1.00 16.62  ? 261 VAL B CG1    1 
ATOM   11339 C CG2    . VAL B 1 261 ? -11.775 11.352  -18.317 1.00 16.04  ? 261 VAL B CG2    1 
ATOM   11340 H H      . VAL B 1 261 ? -10.079 13.453  -18.713 1.00 19.29  ? 261 VAL B H      1 
ATOM   11341 H HA     . VAL B 1 261 ? -8.733  11.320  -19.732 1.00 18.44  ? 261 VAL B HA     1 
ATOM   11342 H HB     . VAL B 1 261 ? -10.711 9.998   -19.426 1.00 16.59  ? 261 VAL B HB     1 
ATOM   11343 H HG11   . VAL B 1 261 ? -10.220 9.390   -17.261 1.00 19.94  ? 261 VAL B HG11   1 
ATOM   11344 H HG12   . VAL B 1 261 ? -8.855  9.748   -17.991 1.00 19.94  ? 261 VAL B HG12   1 
ATOM   11345 H HG13   . VAL B 1 261 ? -9.519  10.791  -16.995 1.00 19.94  ? 261 VAL B HG13   1 
ATOM   11346 H HG21   . VAL B 1 261 ? -12.354 10.656  -17.969 1.00 19.25  ? 261 VAL B HG21   1 
ATOM   11347 H HG22   . VAL B 1 261 ? -11.564 11.988  -17.616 1.00 19.25  ? 261 VAL B HG22   1 
ATOM   11348 H HG23   . VAL B 1 261 ? -12.211 11.804  -19.056 1.00 19.25  ? 261 VAL B HG23   1 
ATOM   11349 N N      . ASN B 1 262 ? -10.284 11.069  -21.771 1.00 14.13  ? 262 ASN B N      1 
ATOM   11350 C CA     . ASN B 1 262 ? -10.745 11.230  -23.142 1.00 15.08  ? 262 ASN B CA     1 
ATOM   11351 C C      . ASN B 1 262 ? -12.215 10.822  -23.312 1.00 14.84  ? 262 ASN B C      1 
ATOM   11352 O O      . ASN B 1 262 ? -12.825 11.071  -24.353 1.00 17.54  ? 262 ASN B O      1 
ATOM   11353 C CB     . ASN B 1 262 ? -9.846  10.415  -24.079 1.00 15.01  ? 262 ASN B CB     1 
ATOM   11354 C CG     . ASN B 1 262 ? -8.362  10.730  -23.885 1.00 16.17  ? 262 ASN B CG     1 
ATOM   11355 O OD1    . ASN B 1 262 ? -7.562  9.866   -23.530 1.00 17.84  ? 262 ASN B OD1    1 
ATOM   11356 N ND2    . ASN B 1 262 ? -8.000  11.980  -24.102 1.00 15.48  ? 262 ASN B ND2    1 
ATOM   11357 H H      . ASN B 1 262 ? -10.079 10.258  -21.571 1.00 16.95  ? 262 ASN B H      1 
ATOM   11358 H HA     . ASN B 1 262 ? -10.665 12.161  -23.397 1.00 18.10  ? 262 ASN B HA     1 
ATOM   11359 H HB2    . ASN B 1 262 ? -9.979  9.470   -23.903 1.00 18.02  ? 262 ASN B HB2    1 
ATOM   11360 H HB3    . ASN B 1 262 ? -10.079 10.618  -24.998 1.00 18.02  ? 262 ASN B HB3    1 
ATOM   11361 H HD21   . ASN B 1 262 ? -7.177  12.212  -24.007 1.00 18.58  ? 262 ASN B HD21   1 
ATOM   11362 H HD22   . ASN B 1 262 ? -8.587  12.563  -24.338 1.00 18.58  ? 262 ASN B HD22   1 
ATOM   11363 N N      . ILE B 1 263 ? -12.773 10.206  -22.278 1.00 16.51  ? 263 ILE B N      1 
ATOM   11364 C CA     . ILE B 1 263 ? -14.170 9.787   -22.270 1.00 15.07  ? 263 ILE B CA     1 
ATOM   11365 C C      . ILE B 1 263 ? -14.526 9.535   -20.814 1.00 18.35  ? 263 ILE B C      1 
ATOM   11366 O O      . ILE B 1 263 ? -13.636 9.275   -20.006 1.00 16.70  ? 263 ILE B O      1 
ATOM   11367 C CB     . ILE B 1 263 ? -14.400 8.522   -23.139 1.00 17.65  ? 263 ILE B CB     1 
ATOM   11368 C CG1    . ILE B 1 263 ? -15.892 8.290   -23.403 1.00 20.58  ? 263 ILE B CG1    1 
ATOM   11369 C CG2    . ILE B 1 263 ? -13.758 7.280   -22.487 1.00 18.26  ? 263 ILE B CG2    1 
ATOM   11370 C CD1    . ILE B 1 263 ? -16.542 9.358   -24.251 1.00 20.52  ? 263 ILE B CD1    1 
ATOM   11371 H H      . ILE B 1 263 ? -12.356 10.012  -21.551 1.00 19.81  ? 263 ILE B H      1 
ATOM   11372 H HA     . ILE B 1 263 ? -14.725 10.507  -22.605 1.00 18.08  ? 263 ILE B HA     1 
ATOM   11373 H HB     . ILE B 1 263 ? -13.966 8.666   -23.994 1.00 21.18  ? 263 ILE B HB     1 
ATOM   11374 H HG12   . ILE B 1 263 ? -15.997 7.444   -23.865 1.00 24.70  ? 263 ILE B HG12   1 
ATOM   11375 H HG13   . ILE B 1 263 ? -16.360 8.259   -22.555 1.00 24.70  ? 263 ILE B HG13   1 
ATOM   11376 H HG21   . ILE B 1 263 ? -13.710 6.569   -23.145 1.00 21.91  ? 263 ILE B HG21   1 
ATOM   11377 H HG22   . ILE B 1 263 ? -12.866 7.510   -22.182 1.00 21.91  ? 263 ILE B HG22   1 
ATOM   11378 H HG23   . ILE B 1 263 ? -14.302 6.999   -21.735 1.00 21.91  ? 263 ILE B HG23   1 
ATOM   11379 H HD11   . ILE B 1 263 ? -17.450 9.088   -24.455 1.00 24.63  ? 263 ILE B HD11   1 
ATOM   11380 H HD12   . ILE B 1 263 ? -16.552 10.194  -23.760 1.00 24.63  ? 263 ILE B HD12   1 
ATOM   11381 H HD13   . ILE B 1 263 ? -16.036 9.461   -25.072 1.00 24.63  ? 263 ILE B HD13   1 
ATOM   11382 N N      . GLY B 1 264 ? -15.805 9.632   -20.465 1.00 17.68  ? 264 GLY B N      1 
ATOM   11383 C CA     . GLY B 1 264 ? -16.229 9.368   -19.095 1.00 19.13  ? 264 GLY B CA     1 
ATOM   11384 C C      . GLY B 1 264 ? -16.972 10.502  -18.432 1.00 17.77  ? 264 GLY B C      1 
ATOM   11385 O O      . GLY B 1 264 ? -16.743 11.684  -18.722 1.00 18.35  ? 264 GLY B O      1 
ATOM   11386 H H      . GLY B 1 264 ? -16.443 9.848   -20.999 1.00 21.22  ? 264 GLY B H      1 
ATOM   11387 H HA2    . GLY B 1 264 ? -16.816 8.598   -19.092 1.00 22.96  ? 264 GLY B HA2    1 
ATOM   11388 H HA3    . GLY B 1 264 ? -15.463 9.156   -18.540 1.00 22.96  ? 264 GLY B HA3    1 
ATOM   11389 N N      . GLY B 1 265 ? -17.866 10.128  -17.523 1.00 18.85  ? 265 GLY B N      1 
ATOM   11390 C CA     . GLY B 1 265 ? -18.635 11.082  -16.742 1.00 19.36  ? 265 GLY B CA     1 
ATOM   11391 C C      . GLY B 1 265 ? -19.337 10.356  -15.616 1.00 17.25  ? 265 GLY B C      1 
ATOM   11392 O O      . GLY B 1 265 ? -19.196 9.143   -15.467 1.00 18.36  ? 265 GLY B O      1 
ATOM   11393 H H      . GLY B 1 265 ? -18.047 9.308   -17.338 1.00 22.62  ? 265 GLY B H      1 
ATOM   11394 H HA2    . GLY B 1 265 ? -18.047 11.757  -16.367 1.00 23.23  ? 265 GLY B HA2    1 
ATOM   11395 H HA3    . GLY B 1 265 ? -19.298 11.515  -17.303 1.00 23.23  ? 265 GLY B HA3    1 
ATOM   11396 N N      . PHE B 1 266 ? -20.089 11.092  -14.805 1.00 19.28  ? 266 PHE B N      1 
ATOM   11397 C CA     . PHE B 1 266 ? -20.915 10.451  -13.797 1.00 16.92  ? 266 PHE B CA     1 
ATOM   11398 C C      . PHE B 1 266 ? -21.956 11.385  -13.215 1.00 18.39  ? 266 PHE B C      1 
ATOM   11399 O O      . PHE B 1 266 ? -21.897 12.596  -13.390 1.00 18.41  ? 266 PHE B O      1 
ATOM   11400 C CB     . PHE B 1 266 ? -20.055 9.868   -12.670 1.00 20.04  ? 266 PHE B CB     1 
ATOM   11401 C CG     . PHE B 1 266 ? -19.029 10.819  -12.106 1.00 21.32  ? 266 PHE B CG     1 
ATOM   11402 C CD1    . PHE B 1 266 ? -19.351 11.667  -11.061 1.00 21.58  ? 266 PHE B CD1    1 
ATOM   11403 C CD2    . PHE B 1 266 ? -17.736 10.848  -12.611 1.00 20.64  ? 266 PHE B CD2    1 
ATOM   11404 C CE1    . PHE B 1 266 ? -18.404 12.536  -10.528 1.00 19.07  ? 266 PHE B CE1    1 
ATOM   11405 C CE2    . PHE B 1 266 ? -16.793 11.710  -12.087 1.00 18.43  ? 266 PHE B CE2    1 
ATOM   11406 C CZ     . PHE B 1 266 ? -17.127 12.553  -11.036 1.00 21.08  ? 266 PHE B CZ     1 
ATOM   11407 H H      . PHE B 1 266 ? -20.137 11.951  -14.819 1.00 23.14  ? 266 PHE B H      1 
ATOM   11408 H HA     . PHE B 1 266 ? -21.389 9.714   -14.213 1.00 20.31  ? 266 PHE B HA     1 
ATOM   11409 H HB2    . PHE B 1 266 ? -20.638 9.603   -11.942 1.00 24.05  ? 266 PHE B HB2    1 
ATOM   11410 H HB3    . PHE B 1 266 ? -19.582 9.091   -13.005 1.00 24.05  ? 266 PHE B HB3    1 
ATOM   11411 H HD1    . PHE B 1 266 ? -20.212 11.653  -10.711 1.00 25.89  ? 266 PHE B HD1    1 
ATOM   11412 H HD2    . PHE B 1 266 ? -17.503 10.282  -13.311 1.00 24.77  ? 266 PHE B HD2    1 
ATOM   11413 H HE1    . PHE B 1 266 ? -18.634 13.102  -9.827  1.00 22.88  ? 266 PHE B HE1    1 
ATOM   11414 H HE2    . PHE B 1 266 ? -15.930 11.721  -12.435 1.00 22.12  ? 266 PHE B HE2    1 
ATOM   11415 H HZ     . PHE B 1 266 ? -16.493 13.137  -10.687 1.00 25.29  ? 266 PHE B HZ     1 
ATOM   11416 N N      . LEU B 1 267 ? -22.914 10.769  -12.538 1.00 20.79  ? 267 LEU B N      1 
ATOM   11417 C CA     . LEU B 1 267 ? -23.968 11.457  -11.805 1.00 21.41  ? 267 LEU B CA     1 
ATOM   11418 C C      . LEU B 1 267 ? -23.791 11.151  -10.329 1.00 21.60  ? 267 LEU B C      1 
ATOM   11419 O O      . LEU B 1 267 ? -23.685 9.981   -9.964  1.00 22.37  ? 267 LEU B O      1 
ATOM   11420 C CB     . LEU B 1 267 ? -25.348 10.996  -12.294 1.00 23.96  ? 267 LEU B CB     1 
ATOM   11421 C CG     . LEU B 1 267 ? -26.580 11.419  -11.484 1.00 23.44  ? 267 LEU B CG     1 
ATOM   11422 C CD1    . LEU B 1 267 ? -26.878 12.902  -11.678 1.00 23.74  ? 267 LEU B CD1    1 
ATOM   11423 C CD2    . LEU B 1 267 ? -27.773 10.553  -11.871 1.00 29.51  ? 267 LEU B CD2    1 
ATOM   11424 H H      . LEU B 1 267 ? -22.977 9.913   -12.487 1.00 24.95  ? 267 LEU B H      1 
ATOM   11425 H HA     . LEU B 1 267 ? -23.896 12.415  -11.935 1.00 25.70  ? 267 LEU B HA     1 
ATOM   11426 H HB2    . LEU B 1 267 ? -25.474 11.334  -13.194 1.00 28.76  ? 267 LEU B HB2    1 
ATOM   11427 H HB3    . LEU B 1 267 ? -25.346 10.026  -12.318 1.00 28.76  ? 267 LEU B HB3    1 
ATOM   11428 H HG     . LEU B 1 267 ? -26.408 11.274  -10.542 1.00 28.13  ? 267 LEU B HG     1 
ATOM   11429 H HD11   . LEU B 1 267 ? -27.671 13.133  -11.169 1.00 28.48  ? 267 LEU B HD11   1 
ATOM   11430 H HD12   . LEU B 1 267 ? -26.121 13.419  -11.364 1.00 28.48  ? 267 LEU B HD12   1 
ATOM   11431 H HD13   . LEU B 1 267 ? -27.028 13.073  -12.621 1.00 28.48  ? 267 LEU B HD13   1 
ATOM   11432 H HD21   . LEU B 1 267 ? -28.548 10.839  -11.363 1.00 35.42  ? 267 LEU B HD21   1 
ATOM   11433 H HD22   . LEU B 1 267 ? -27.943 10.656  -12.820 1.00 35.42  ? 267 LEU B HD22   1 
ATOM   11434 H HD23   . LEU B 1 267 ? -27.569 9.626   -11.670 1.00 35.42  ? 267 LEU B HD23   1 
ATOM   11435 N N      . CYS B 1 268 ? -23.715 12.192  -9.495  1.00 20.43  ? 268 CYS B N      1 
ATOM   11436 C CA     . CYS B 1 268 ? -23.712 12.015  -8.041  1.00 19.49  ? 268 CYS B CA     1 
ATOM   11437 C C      . CYS B 1 268 ? -24.975 12.559  -7.407  1.00 21.09  ? 268 CYS B C      1 
ATOM   11438 O O      . CYS B 1 268 ? -25.589 13.505  -7.908  1.00 21.43  ? 268 CYS B O      1 
ATOM   11439 C CB     . CYS B 1 268 ? -22.533 12.711  -7.373  1.00 25.09  ? 268 CYS B CB     1 
ATOM   11440 S SG     . CYS B 1 268 ? -20.910 12.232  -7.951  1.00 27.78  ? 268 CYS B SG     1 
ATOM   11441 H H      . CYS B 1 268 ? -23.664 13.013  -9.748  1.00 24.51  ? 268 CYS B H      1 
ATOM   11442 H HA     . CYS B 1 268 ? -23.657 11.072  -7.829  1.00 23.39  ? 268 CYS B HA     1 
ATOM   11443 H HB2    . CYS B 1 268 ? -22.629 13.665  -7.507  1.00 30.11  ? 268 CYS B HB2    1 
ATOM   11444 H HB3    . CYS B 1 268 ? -22.567 12.517  -6.424  1.00 30.11  ? 268 CYS B HB3    1 
ATOM   11445 H HG     . CYS B 1 268 ? -20.798 12.691  -9.052  1.00 33.34  ? 268 CYS B HG     1 
ATOM   11446 N N      . MET B 1 269 ? -25.336 11.965  -6.277  1.00 21.41  ? 269 MET B N      1 
ATOM   11447 C CA     . MET B 1 269 ? -26.477 12.423  -5.506  1.00 26.62  ? 269 MET B CA     1 
ATOM   11448 C C      . MET B 1 269 ? -26.360 11.906  -4.081  1.00 28.03  ? 269 MET B C      1 
ATOM   11449 O O      . MET B 1 269 ? -25.711 10.886  -3.827  1.00 25.80  ? 269 MET B O      1 
ATOM   11450 C CB     . MET B 1 269 ? -27.784 11.956  -6.143  1.00 26.65  ? 269 MET B CB     1 
ATOM   11451 C CG     . MET B 1 269 ? -28.074 10.477  -5.936  1.00 34.85  ? 269 MET B CG     1 
ATOM   11452 S SD     . MET B 1 269 ? -28.316 9.617   -7.491  1.00 47.85  ? 269 MET B SD     1 
ATOM   11453 C CE     . MET B 1 269 ? -26.688 9.727   -8.227  1.00 41.64  ? 269 MET B CE     1 
ATOM   11454 H H      . MET B 1 269 ? -24.931 11.288  -5.934  1.00 25.69  ? 269 MET B H      1 
ATOM   11455 H HA     . MET B 1 269 ? -26.481 13.393  -5.490  1.00 31.95  ? 269 MET B HA     1 
ATOM   11456 H HB2    . MET B 1 269 ? -28.517 12.459  -5.755  1.00 31.98  ? 269 MET B HB2    1 
ATOM   11457 H HB3    . MET B 1 269 ? -27.743 12.120  -7.098  1.00 31.98  ? 269 MET B HB3    1 
ATOM   11458 H HG2    . MET B 1 269 ? -27.331 10.046  -5.490  1.00 41.82  ? 269 MET B HG2    1 
ATOM   11459 H HG3    . MET B 1 269 ? -28.882 10.381  -5.408  1.00 41.82  ? 269 MET B HG3    1 
ATOM   11460 H HE1    . MET B 1 269 ? -26.674 9.200   -9.041  1.00 49.96  ? 269 MET B HE1    1 
ATOM   11461 H HE2    . MET B 1 269 ? -26.500 10.655  -8.431  1.00 49.96  ? 269 MET B HE2    1 
ATOM   11462 H HE3    . MET B 1 269 ? -26.033 9.384   -7.599  1.00 49.96  ? 269 MET B HE3    1 
ATOM   11463 N N      . ASN B 1 270 ? -26.988 12.622  -3.158  1.00 25.28  ? 270 ASN B N      1 
ATOM   11464 C CA     . ASN B 1 270 ? -27.010 12.223  -1.761  1.00 27.80  ? 270 ASN B CA     1 
ATOM   11465 C C      . ASN B 1 270 ? -28.268 11.431  -1.406  1.00 30.17  ? 270 ASN B C      1 
ATOM   11466 O O      . ASN B 1 270 ? -28.247 10.599  -0.501  1.00 30.77  ? 270 ASN B O      1 
ATOM   11467 C CB     . ASN B 1 270 ? -26.892 13.463  -0.873  1.00 28.47  ? 270 ASN B CB     1 
ATOM   11468 C CG     . ASN B 1 270 ? -25.498 14.044  -0.884  1.00 26.04  ? 270 ASN B CG     1 
ATOM   11469 O OD1    . ASN B 1 270 ? -24.509 13.306  -0.948  1.00 27.90  ? 270 ASN B OD1    1 
ATOM   11470 N ND2    . ASN B 1 270 ? -25.406 15.368  -0.822  1.00 29.21  ? 270 ASN B ND2    1 
ATOM   11471 H H      . ASN B 1 270 ? -27.414 13.352  -3.319  1.00 30.34  ? 270 ASN B H      1 
ATOM   11472 H HA     . ASN B 1 270 ? -26.247 11.654  -1.577  1.00 33.36  ? 270 ASN B HA     1 
ATOM   11473 H HB2    . ASN B 1 270 ? -27.505 14.143  -1.194  1.00 34.17  ? 270 ASN B HB2    1 
ATOM   11474 H HB3    . ASN B 1 270 ? -27.111 13.221  0.041   1.00 34.17  ? 270 ASN B HB3    1 
ATOM   11475 H HD21   . ASN B 1 270 ? -24.634 15.746  -0.826  1.00 35.06  ? 270 ASN B HD21   1 
ATOM   11476 H HD22   . ASN B 1 270 ? -26.119 15.847  -0.778  1.00 35.06  ? 270 ASN B HD22   1 
ATOM   11477 N N      . ASP B 1 271 ? -29.351 11.683  -2.134  1.00 32.19  ? 271 ASP B N      1 
ATOM   11478 C CA     . ASP B 1 271 ? -30.660 11.111  -1.805  1.00 36.61  ? 271 ASP B CA     1 
ATOM   11479 C C      . ASP B 1 271 ? -30.774 9.633   -2.188  1.00 36.95  ? 271 ASP B C      1 
ATOM   11480 O O      . ASP B 1 271 ? -30.597 9.267   -3.350  1.00 29.57  ? 271 ASP B O      1 
ATOM   11481 C CB     . ASP B 1 271 ? -31.770 11.912  -2.499  1.00 34.96  ? 271 ASP B CB     1 
ATOM   11482 C CG     . ASP B 1 271 ? -33.162 11.484  -2.059  1.00 42.10  ? 271 ASP B CG     1 
ATOM   11483 O OD1    . ASP B 1 271 ? -33.540 11.780  -0.906  1.00 49.65  ? 271 ASP B OD1    1 
ATOM   11484 O OD2    . ASP B 1 271 ? -33.877 10.853  -2.863  1.00 37.29  ? 271 ASP B OD2    1 
ATOM   11485 H H      . ASP B 1 271 ? -29.358 12.187  -2.831  1.00 38.62  ? 271 ASP B H      1 
ATOM   11486 H HA     . ASP B 1 271 ? -30.799 11.180  -0.848  1.00 43.93  ? 271 ASP B HA     1 
ATOM   11487 H HB2    . ASP B 1 271 ? -31.663 12.852  -2.285  1.00 41.95  ? 271 ASP B HB2    1 
ATOM   11488 H HB3    . ASP B 1 271 ? -31.704 11.780  -3.458  1.00 41.95  ? 271 ASP B HB3    1 
ATOM   11489 N N      . ASP B 1 272 ? -31.087 8.794   -1.203  1.00 33.07  ? 272 ASP B N      1 
ATOM   11490 C CA     . ASP B 1 272 ? -31.196 7.352   -1.414  1.00 35.77  ? 272 ASP B CA     1 
ATOM   11491 C C      . ASP B 1 272 ? -32.233 6.986   -2.475  1.00 35.03  ? 272 ASP B C      1 
ATOM   11492 O O      . ASP B 1 272 ? -31.975 6.143   -3.337  1.00 33.77  ? 272 ASP B O      1 
ATOM   11493 C CB     . ASP B 1 272 ? -31.552 6.644   -0.103  1.00 37.59  ? 272 ASP B CB     1 
ATOM   11494 C CG     . ASP B 1 272 ? -30.387 6.577   0.875   1.00 44.07  ? 272 ASP B CG     1 
ATOM   11495 O OD1    . ASP B 1 272 ? -29.239 6.919   0.504   1.00 35.99  ? 272 ASP B OD1    1 
ATOM   11496 O OD2    . ASP B 1 272 ? -30.624 6.162   2.028   1.00 43.87  ? 272 ASP B OD2    1 
ATOM   11497 H H      . ASP B 1 272 ? -31.243 9.038   -0.393  1.00 39.68  ? 272 ASP B H      1 
ATOM   11498 H HA     . ASP B 1 272 ? -30.339 7.014   -1.716  1.00 42.93  ? 272 ASP B HA     1 
ATOM   11499 H HB2    . ASP B 1 272 ? -32.276 7.124   0.328   1.00 45.11  ? 272 ASP B HB2    1 
ATOM   11500 H HB3    . ASP B 1 272 ? -31.829 5.736   -0.301  1.00 45.11  ? 272 ASP B HB3    1 
ATOM   11501 N N      . ASP B 1 273 ? -33.404 7.614   -2.408  1.00 34.45  ? 273 ASP B N      1 
ATOM   11502 C CA     . ASP B 1 273 ? -34.501 7.284   -3.314  1.00 34.79  ? 273 ASP B CA     1 
ATOM   11503 C C      . ASP B 1 273 ? -34.184 7.689   -4.748  1.00 36.71  ? 273 ASP B C      1 
ATOM   11504 O O      . ASP B 1 273 ? -34.510 6.969   -5.691  1.00 32.25  ? 273 ASP B O      1 
ATOM   11505 C CB     . ASP B 1 273 ? -35.805 7.954   -2.864  1.00 38.50  ? 273 ASP B CB     1 
ATOM   11506 C CG     . ASP B 1 273 ? -36.387 7.325   -1.603  1.00 49.58  ? 273 ASP B CG     1 
ATOM   11507 O OD1    . ASP B 1 273 ? -35.962 6.209   -1.232  1.00 45.89  ? 273 ASP B OD1    1 
ATOM   11508 O OD2    . ASP B 1 273 ? -37.280 7.947   -0.986  1.00 55.91  ? 273 ASP B OD2    1 
ATOM   11509 H H      . ASP B 1 273 ? -33.589 8.237   -1.845  1.00 41.33  ? 273 ASP B H      1 
ATOM   11510 H HA     . ASP B 1 273 ? -34.636 6.324   -3.306  1.00 41.75  ? 273 ASP B HA     1 
ATOM   11511 H HB2    . ASP B 1 273 ? -35.632 8.890   -2.680  1.00 46.20  ? 273 ASP B HB2    1 
ATOM   11512 H HB3    . ASP B 1 273 ? -36.463 7.871   -3.572  1.00 46.20  ? 273 ASP B HB3    1 
ATOM   11513 N N      . MET B 1 274 ? -33.554 8.844   -4.921  1.00 30.27  ? 274 MET B N      1 
ATOM   11514 C CA     . MET B 1 274 ? -33.180 9.264   -6.260  1.00 35.30  ? 274 MET B CA     1 
ATOM   11515 C C      . MET B 1 274 ? -32.130 8.311   -6.828  1.00 31.75  ? 274 MET B C      1 
ATOM   11516 O O      . MET B 1 274 ? -32.162 7.979   -8.011  1.00 29.71  ? 274 MET B O      1 
ATOM   11517 C CB     . MET B 1 274 ? -32.654 10.694  -6.258  1.00 37.37  ? 274 MET B CB     1 
ATOM   11518 C CG     . MET B 1 274 ? -32.234 11.176  -7.636  1.00 41.27  ? 274 MET B CG     1 
ATOM   11519 S SD     . MET B 1 274 ? -31.708 12.893  -7.642  1.00 53.20  ? 274 MET B SD     1 
ATOM   11520 C CE     . MET B 1 274 ? -33.301 13.706  -7.477  1.00 52.35  ? 274 MET B CE     1 
ATOM   11521 H H      . MET B 1 274 ? -33.336 9.391   -4.294  1.00 36.33  ? 274 MET B H      1 
ATOM   11522 H HA     . MET B 1 274 ? -33.966 9.239   -6.828  1.00 42.36  ? 274 MET B HA     1 
ATOM   11523 H HB2    . MET B 1 274 ? -33.351 11.285  -5.934  1.00 44.84  ? 274 MET B HB2    1 
ATOM   11524 H HB3    . MET B 1 274 ? -31.880 10.744  -5.675  1.00 44.84  ? 274 MET B HB3    1 
ATOM   11525 H HG2    . MET B 1 274 ? -31.490 10.639  -7.950  1.00 49.53  ? 274 MET B HG2    1 
ATOM   11526 H HG3    . MET B 1 274 ? -32.985 11.090  -8.244  1.00 49.53  ? 274 MET B HG3    1 
ATOM   11527 H HE1    . MET B 1 274 ? -33.169 14.667  -7.509  1.00 62.82  ? 274 MET B HE1    1 
ATOM   11528 H HE2    . MET B 1 274 ? -33.875 13.426  -8.207  1.00 62.82  ? 274 MET B HE2    1 
ATOM   11529 H HE3    . MET B 1 274 ? -33.698 13.454  -6.629  1.00 62.82  ? 274 MET B HE3    1 
ATOM   11530 N N      . PHE B 1 275 ? -31.203 7.876   -5.980  1.00 33.16  ? 275 PHE B N      1 
ATOM   11531 C CA     . PHE B 1 275 ? -30.167 6.931   -6.392  1.00 30.99  ? 275 PHE B CA     1 
ATOM   11532 C C      . PHE B 1 275 ? -30.785 5.630   -6.891  1.00 34.74  ? 275 PHE B C      1 
ATOM   11533 O O      . PHE B 1 275 ? -30.384 5.111   -7.931  1.00 33.61  ? 275 PHE B O      1 
ATOM   11534 C CB     . PHE B 1 275 ? -29.205 6.663   -5.235  1.00 31.73  ? 275 PHE B CB     1 
ATOM   11535 C CG     . PHE B 1 275 ? -28.149 5.630   -5.533  1.00 32.69  ? 275 PHE B CG     1 
ATOM   11536 C CD1    . PHE B 1 275 ? -27.339 5.746   -6.647  1.00 34.10  ? 275 PHE B CD1    1 
ATOM   11537 C CD2    . PHE B 1 275 ? -27.953 4.557   -4.678  1.00 36.15  ? 275 PHE B CD2    1 
ATOM   11538 C CE1    . PHE B 1 275 ? -26.357 4.807   -6.912  1.00 33.51  ? 275 PHE B CE1    1 
ATOM   11539 C CE2    . PHE B 1 275 ? -26.972 3.610   -4.939  1.00 37.62  ? 275 PHE B CE2    1 
ATOM   11540 C CZ     . PHE B 1 275 ? -26.173 3.739   -6.057  1.00 34.54  ? 275 PHE B CZ     1 
ATOM   11541 H H      . PHE B 1 275 ? -31.151 8.114   -5.155  1.00 39.80  ? 275 PHE B H      1 
ATOM   11542 H HA     . PHE B 1 275 ? -29.661 7.312   -7.124  1.00 37.19  ? 275 PHE B HA     1 
ATOM   11543 H HB2    . PHE B 1 275 ? -28.752 7.491   -5.009  1.00 38.07  ? 275 PHE B HB2    1 
ATOM   11544 H HB3    . PHE B 1 275 ? -29.714 6.351   -4.472  1.00 38.07  ? 275 PHE B HB3    1 
ATOM   11545 H HD1    . PHE B 1 275 ? -27.455 6.465   -7.226  1.00 40.92  ? 275 PHE B HD1    1 
ATOM   11546 H HD2    . PHE B 1 275 ? -28.488 4.468   -3.922  1.00 43.37  ? 275 PHE B HD2    1 
ATOM   11547 H HE1    . PHE B 1 275 ? -25.822 4.895   -7.668  1.00 40.21  ? 275 PHE B HE1    1 
ATOM   11548 H HE2    . PHE B 1 275 ? -26.852 2.892   -4.361  1.00 45.15  ? 275 PHE B HE2    1 
ATOM   11549 H HZ     . PHE B 1 275 ? -25.517 3.105   -6.237  1.00 41.45  ? 275 PHE B HZ     1 
ATOM   11550 N N      . SER B 1 276 ? -31.767 5.113   -6.158  1.00 32.10  ? 276 SER B N      1 
ATOM   11551 C CA     . SER B 1 276 ? -32.480 3.912   -6.580  1.00 34.41  ? 276 SER B CA     1 
ATOM   11552 C C      . SER B 1 276 ? -33.130 4.097   -7.941  1.00 32.63  ? 276 SER B C      1 
ATOM   11553 O O      . SER B 1 276 ? -33.044 3.224   -8.804  1.00 36.01  ? 276 SER B O      1 
ATOM   11554 C CB     . SER B 1 276 ? -33.542 3.528   -5.551  1.00 36.61  ? 276 SER B CB     1 
ATOM   11555 O OG     . SER B 1 276 ? -32.928 3.110   -4.350  1.00 41.10  ? 276 SER B OG     1 
ATOM   11556 H H      . SER B 1 276 ? -32.040 5.440   -5.411  1.00 38.52  ? 276 SER B H      1 
ATOM   11557 H HA     . SER B 1 276 ? -31.849 3.178   -6.647  1.00 41.29  ? 276 SER B HA     1 
ATOM   11558 H HB2    . SER B 1 276 ? -34.103 4.299   -5.370  1.00 43.93  ? 276 SER B HB2    1 
ATOM   11559 H HB3    . SER B 1 276 ? -34.078 2.801   -5.904  1.00 43.93  ? 276 SER B HB3    1 
ATOM   11560 H HG     . SER B 1 276 ? -33.514 2.899   -3.786  1.00 49.32  ? 276 SER B HG     1 
ATOM   11561 N N      . ALA B 1 277 ? -33.770 5.243   -8.139  1.00 30.30  ? 277 ALA B N      1 
ATOM   11562 C CA     . ALA B 1 277 ? -34.442 5.521   -9.395  1.00 30.63  ? 277 ALA B CA     1 
ATOM   11563 C C      . ALA B 1 277 ? -33.425 5.692   -10.526 1.00 36.95  ? 277 ALA B C      1 
ATOM   11564 O O      . ALA B 1 277 ? -33.674 5.284   -11.662 1.00 31.28  ? 277 ALA B O      1 
ATOM   11565 C CB     . ALA B 1 277 ? -35.314 6.759   -9.269  1.00 31.32  ? 277 ALA B CB     1 
ATOM   11566 H H      . ALA B 1 277 ? -33.829 5.876   -7.559  1.00 36.36  ? 277 ALA B H      1 
ATOM   11567 H HA     . ALA B 1 277 ? -35.016 4.772   -9.619  1.00 36.75  ? 277 ALA B HA     1 
ATOM   11568 H HB1    . ALA B 1 277 ? -35.752 6.924   -10.118 1.00 37.59  ? 277 ALA B HB1    1 
ATOM   11569 H HB2    . ALA B 1 277 ? -35.977 6.608   -8.578  1.00 37.59  ? 277 ALA B HB2    1 
ATOM   11570 H HB3    . ALA B 1 277 ? -34.755 7.516   -9.032  1.00 37.59  ? 277 ALA B HB3    1 
ATOM   11571 N N      . ALA B 1 278 ? -32.284 6.300   -10.216 1.00 30.20  ? 278 ALA B N      1 
ATOM   11572 C CA     . ALA B 1 278 ? -31.240 6.504   -11.216 1.00 29.96  ? 278 ALA B CA     1 
ATOM   11573 C C      . ALA B 1 278 ? -30.661 5.168   -11.664 1.00 28.31  ? 278 ALA B C      1 
ATOM   11574 O O      . ALA B 1 278 ? -30.335 4.983   -12.832 1.00 28.66  ? 278 ALA B O      1 
ATOM   11575 C CB     . ALA B 1 278 ? -30.143 7.401   -10.666 1.00 26.07  ? 278 ALA B CB     1 
ATOM   11576 H H      . ALA B 1 278 ? -32.089 6.604   -9.435  1.00 36.24  ? 278 ALA B H      1 
ATOM   11577 H HA     . ALA B 1 278 ? -31.625 6.938   -11.993 1.00 35.95  ? 278 ALA B HA     1 
ATOM   11578 H HB1    . ALA B 1 278 ? -29.463 7.521   -11.347 1.00 31.28  ? 278 ALA B HB1    1 
ATOM   11579 H HB2    . ALA B 1 278 ? -30.527 8.259   -10.427 1.00 31.28  ? 278 ALA B HB2    1 
ATOM   11580 H HB3    . ALA B 1 278 ? -29.756 6.981   -9.882  1.00 31.28  ? 278 ALA B HB3    1 
ATOM   11581 N N      . ARG B 1 279 ? -30.534 4.240   -10.725 1.00 30.67  ? 279 ARG B N      1 
ATOM   11582 C CA     . ARG B 1 279 ? -30.022 2.908   -11.027 1.00 31.77  ? 279 ARG B CA     1 
ATOM   11583 C C      . ARG B 1 279 ? -30.881 2.168   -12.051 1.00 33.86  ? 279 ARG B C      1 
ATOM   11584 O O      . ARG B 1 279 ? -30.353 1.525   -12.954 1.00 32.35  ? 279 ARG B O      1 
ATOM   11585 C CB     . ARG B 1 279 ? -29.922 2.080   -9.746  1.00 36.09  ? 279 ARG B CB     1 
ATOM   11586 C CG     . ARG B 1 279 ? -28.567 2.142   -9.076  1.00 39.25  ? 279 ARG B CG     1 
ATOM   11587 C CD     . ARG B 1 279 ? -28.615 1.506   -7.695  1.00 38.96  ? 279 ARG B CD     1 
ATOM   11588 N NE     . ARG B 1 279 ? -27.475 0.633   -7.463  1.00 53.04  ? 279 ARG B NE     1 
ATOM   11589 C CZ     . ARG B 1 279 ? -27.193 0.065   -6.295  1.00 63.16  ? 279 ARG B CZ     1 
ATOM   11590 N NH1    . ARG B 1 279 ? -27.973 0.281   -5.241  1.00 56.79  ? 279 ARG B NH1    1 
ATOM   11591 N NH2    . ARG B 1 279 ? -26.126 -0.719  -6.181  1.00 55.42  ? 279 ARG B NH2    1 
ATOM   11592 H H      . ARG B 1 279 ? -30.738 4.357   -9.898  1.00 36.81  ? 279 ARG B H      1 
ATOM   11593 H HA     . ARG B 1 279 ? -29.129 2.993   -11.396 1.00 38.13  ? 279 ARG B HA     1 
ATOM   11594 H HB2    . ARG B 1 279 ? -30.580 2.403   -9.112  1.00 43.31  ? 279 ARG B HB2    1 
ATOM   11595 H HB3    . ARG B 1 279 ? -30.103 1.152   -9.961  1.00 43.31  ? 279 ARG B HB3    1 
ATOM   11596 H HG2    . ARG B 1 279 ? -27.920 1.659   -9.614  1.00 47.10  ? 279 ARG B HG2    1 
ATOM   11597 H HG3    . ARG B 1 279 ? -28.299 3.069   -8.977  1.00 47.10  ? 279 ARG B HG3    1 
ATOM   11598 H HD2    . ARG B 1 279 ? -28.604 2.204   -7.022  1.00 46.75  ? 279 ARG B HD2    1 
ATOM   11599 H HD3    . ARG B 1 279 ? -29.424 0.976   -7.615  1.00 46.75  ? 279 ARG B HD3    1 
ATOM   11600 H HE     . ARG B 1 279 ? -26.967 0.449   -8.132  1.00 63.65  ? 279 ARG B HE     1 
ATOM   11601 H HH11   . ARG B 1 279 ? -28.664 0.788   -5.309  1.00 68.15  ? 279 ARG B HH11   1 
ATOM   11602 H HH12   . ARG B 1 279 ? -27.786 -0.089  -4.487  1.00 68.15  ? 279 ARG B HH12   1 
ATOM   11603 H HH21   . ARG B 1 279 ? -25.620 -0.859  -6.862  1.00 66.50  ? 279 ARG B HH21   1 
ATOM   11604 H HH22   . ARG B 1 279 ? -25.942 -1.087  -5.426  1.00 66.50  ? 279 ARG B HH22   1 
ATOM   11605 N N      . GLU B 1 280 ? -32.201 2.245   -11.933 1.00 35.23  ? 280 GLU B N      1 
ATOM   11606 C CA     . GLU B 1 280 ? -33.031 1.523   -12.888 1.00 36.28  ? 280 GLU B CA     1 
ATOM   11607 C C      . GLU B 1 280 ? -33.116 2.279   -14.205 1.00 32.86  ? 280 GLU B C      1 
ATOM   11608 O O      . GLU B 1 280 ? -33.271 1.666   -15.254 1.00 33.38  ? 280 GLU B O      1 
ATOM   11609 C CB     . GLU B 1 280 ? -34.430 1.243   -12.329 1.00 45.04  ? 280 GLU B CB     1 
ATOM   11610 C CG     . GLU B 1 280 ? -35.308 2.442   -12.080 1.00 51.53  ? 280 GLU B CG     1 
ATOM   11611 C CD     . GLU B 1 280 ? -36.693 2.030   -11.593 1.00 70.04  ? 280 GLU B CD     1 
ATOM   11612 O OE1    . GLU B 1 280 ? -37.283 1.099   -12.188 1.00 56.64  ? 280 GLU B OE1    1 
ATOM   11613 O OE2    . GLU B 1 280 ? -37.183 2.622   -10.605 1.00 76.66  ? 280 GLU B OE2    1 
ATOM   11614 H H      . GLU B 1 280 ? -32.628 2.690   -11.333 1.00 42.28  ? 280 GLU B H      1 
ATOM   11615 H HA     . GLU B 1 280 ? -32.624 0.662   -13.072 1.00 43.53  ? 280 GLU B HA     1 
ATOM   11616 H HB2    . GLU B 1 280 ? -34.896 0.669   -12.957 1.00 54.05  ? 280 GLU B HB2    1 
ATOM   11617 H HB3    . GLU B 1 280 ? -34.331 0.778   -11.483 1.00 54.05  ? 280 GLU B HB3    1 
ATOM   11618 H HG2    . GLU B 1 280 ? -34.901 3.000   -11.399 1.00 61.83  ? 280 GLU B HG2    1 
ATOM   11619 H HG3    . GLU B 1 280 ? -35.414 2.941   -12.905 1.00 61.83  ? 280 GLU B HG3    1 
ATOM   11620 N N      . LEU B 1 281 ? -32.978 3.601   -14.170 1.00 29.35  ? 281 LEU B N      1 
ATOM   11621 C CA     . LEU B 1 281 ? -33.034 4.378   -15.402 1.00 28.93  ? 281 LEU B CA     1 
ATOM   11622 C C      . LEU B 1 281 ? -31.743 4.243   -16.225 1.00 30.62  ? 281 LEU B C      1 
ATOM   11623 O O      . LEU B 1 281 ? -31.787 4.172   -17.460 1.00 28.15  ? 281 LEU B O      1 
ATOM   11624 C CB     . LEU B 1 281 ? -33.309 5.853   -15.089 1.00 31.76  ? 281 LEU B CB     1 
ATOM   11625 C CG     . LEU B 1 281 ? -33.598 6.774   -16.275 1.00 34.27  ? 281 LEU B CG     1 
ATOM   11626 C CD1    . LEU B 1 281 ? -34.786 6.295   -17.102 1.00 38.36  ? 281 LEU B CD1    1 
ATOM   11627 C CD2    . LEU B 1 281 ? -33.847 8.193   -15.767 1.00 32.66  ? 281 LEU B CD2    1 
ATOM   11628 H H      . LEU B 1 281 ? -32.853 4.066   -13.457 1.00 35.22  ? 281 LEU B H      1 
ATOM   11629 H HA     . LEU B 1 281 ? -33.767 4.048   -15.945 1.00 34.72  ? 281 LEU B HA     1 
ATOM   11630 H HB2    . LEU B 1 281 ? -34.078 5.898   -14.499 1.00 38.11  ? 281 LEU B HB2    1 
ATOM   11631 H HB3    . LEU B 1 281 ? -32.534 6.213   -14.630 1.00 38.11  ? 281 LEU B HB3    1 
ATOM   11632 H HG     . LEU B 1 281 ? -32.820 6.796   -16.854 1.00 41.12  ? 281 LEU B HG     1 
ATOM   11633 H HD11   . LEU B 1 281 ? -35.001 6.971   -17.764 1.00 46.03  ? 281 LEU B HD11   1 
ATOM   11634 H HD12   . LEU B 1 281 ? -34.551 5.464   -17.543 1.00 46.03  ? 281 LEU B HD12   1 
ATOM   11635 H HD13   . LEU B 1 281 ? -35.544 6.156   -16.513 1.00 46.03  ? 281 LEU B HD13   1 
ATOM   11636 H HD21   . LEU B 1 281 ? -34.034 8.770   -16.524 1.00 39.19  ? 281 LEU B HD21   1 
ATOM   11637 H HD22   . LEU B 1 281 ? -34.606 8.183   -15.162 1.00 39.19  ? 281 LEU B HD22   1 
ATOM   11638 H HD23   . LEU B 1 281 ? -33.056 8.505   -15.301 1.00 39.19  ? 281 LEU B HD23   1 
ATOM   11639 N N      . VAL B 1 282 ? -30.596 4.194   -15.550 1.00 27.10  ? 282 VAL B N      1 
ATOM   11640 C CA     . VAL B 1 282 ? -29.317 4.172   -16.254 1.00 27.24  ? 282 VAL B CA     1 
ATOM   11641 C C      . VAL B 1 282 ? -29.203 2.917   -17.123 1.00 26.98  ? 282 VAL B C      1 
ATOM   11642 O O      . VAL B 1 282 ? -28.597 2.958   -18.194 1.00 21.48  ? 282 VAL B O      1 
ATOM   11643 C CB     . VAL B 1 282 ? -28.113 4.253   -15.269 1.00 26.66  ? 282 VAL B CB     1 
ATOM   11644 C CG1    . VAL B 1 282 ? -27.985 2.990   -14.435 1.00 26.84  ? 282 VAL B CG1    1 
ATOM   11645 C CG2    . VAL B 1 282 ? -26.818 4.529   -16.027 1.00 26.68  ? 282 VAL B CG2    1 
ATOM   11646 H H      . VAL B 1 282 ? -30.532 4.173   -14.693 1.00 32.53  ? 282 VAL B H      1 
ATOM   11647 H HA     . VAL B 1 282 ? -29.271 4.942   -16.841 1.00 32.69  ? 282 VAL B HA     1 
ATOM   11648 H HB     . VAL B 1 282 ? -28.260 4.993   -14.660 1.00 31.99  ? 282 VAL B HB     1 
ATOM   11649 H HG11   . VAL B 1 282 ? -27.190 3.062   -13.884 1.00 32.21  ? 282 VAL B HG11   1 
ATOM   11650 H HG12   . VAL B 1 282 ? -28.765 2.923   -13.871 1.00 32.21  ? 282 VAL B HG12   1 
ATOM   11651 H HG13   . VAL B 1 282 ? -27.912 2.213   -15.010 1.00 32.21  ? 282 VAL B HG13   1 
ATOM   11652 H HG21   . VAL B 1 282 ? -26.122 4.754   -15.390 1.00 32.02  ? 282 VAL B HG21   1 
ATOM   11653 H HG22   . VAL B 1 282 ? -26.568 3.733   -16.522 1.00 32.02  ? 282 VAL B HG22   1 
ATOM   11654 H HG23   . VAL B 1 282 ? -26.960 5.270   -16.636 1.00 32.02  ? 282 VAL B HG23   1 
ATOM   11655 N N      . VAL B 1 283 ? -29.805 1.817   -16.672 1.00 24.31  ? 283 VAL B N      1 
ATOM   11656 C CA     . VAL B 1 283 ? -29.743 0.547   -17.401 1.00 23.60  ? 283 VAL B CA     1 
ATOM   11657 C C      . VAL B 1 283 ? -30.153 0.681   -18.870 1.00 26.89  ? 283 VAL B C      1 
ATOM   11658 O O      . VAL B 1 283 ? -29.516 0.101   -19.751 1.00 26.13  ? 283 VAL B O      1 
ATOM   11659 C CB     . VAL B 1 283 ? -30.646 -0.530  -16.729 1.00 24.31  ? 283 VAL B CB     1 
ATOM   11660 C CG1    . VAL B 1 283 ? -30.691 -1.811  -17.556 1.00 28.90  ? 283 VAL B CG1    1 
ATOM   11661 C CG2    . VAL B 1 283 ? -30.158 -0.833  -15.324 1.00 27.81  ? 283 VAL B CG2    1 
ATOM   11662 H H      . VAL B 1 283 ? -30.259 1.779   -15.943 1.00 29.18  ? 283 VAL B H      1 
ATOM   11663 H HA     . VAL B 1 283 ? -28.831 0.219   -17.379 1.00 28.32  ? 283 VAL B HA     1 
ATOM   11664 H HB     . VAL B 1 283 ? -31.550 -0.185  -16.663 1.00 29.18  ? 283 VAL B HB     1 
ATOM   11665 H HG11   . VAL B 1 283 ? -31.003 -2.536  -16.993 1.00 34.68  ? 283 VAL B HG11   1 
ATOM   11666 H HG12   . VAL B 1 283 ? -31.299 -1.688  -18.302 1.00 34.68  ? 283 VAL B HG12   1 
ATOM   11667 H HG13   . VAL B 1 283 ? -29.799 -2.008  -17.882 1.00 34.68  ? 283 VAL B HG13   1 
ATOM   11668 H HG21   . VAL B 1 283 ? -30.829 -1.362  -14.865 1.00 33.38  ? 283 VAL B HG21   1 
ATOM   11669 H HG22   . VAL B 1 283 ? -29.327 -1.329  -15.380 1.00 33.38  ? 283 VAL B HG22   1 
ATOM   11670 H HG23   . VAL B 1 283 ? -30.014 0.000   -14.852 1.00 33.38  ? 283 VAL B HG23   1 
ATOM   11671 N N      . VAL B 1 284 ? -31.203 1.443   -19.152 1.00 26.29  ? 284 VAL B N      1 
ATOM   11672 C CA     . VAL B 1 284 ? -31.724 1.465   -20.520 1.00 27.78  ? 284 VAL B CA     1 
ATOM   11673 C C      . VAL B 1 284 ? -31.041 2.501   -21.410 1.00 28.21  ? 284 VAL B C      1 
ATOM   11674 O O      . VAL B 1 284 ? -31.093 2.370   -22.634 1.00 26.60  ? 284 VAL B O      1 
ATOM   11675 C CB     . VAL B 1 284 ? -33.256 1.702   -20.543 1.00 33.69  ? 284 VAL B CB     1 
ATOM   11676 C CG1    . VAL B 1 284 ? -33.970 0.514   -19.910 1.00 30.29  ? 284 VAL B CG1    1 
ATOM   11677 C CG2    . VAL B 1 284 ? -33.629 2.989   -19.839 1.00 29.21  ? 284 VAL B CG2    1 
ATOM   11678 H H      . VAL B 1 284 ? -31.621 1.942   -18.591 1.00 31.54  ? 284 VAL B H      1 
ATOM   11679 H HA     . VAL B 1 284 ? -31.572 0.596   -20.923 1.00 33.33  ? 284 VAL B HA     1 
ATOM   11680 H HB     . VAL B 1 284 ? -33.550 1.770   -21.465 1.00 40.43  ? 284 VAL B HB     1 
ATOM   11681 H HG11   . VAL B 1 284 ? -34.927 0.669   -19.939 1.00 36.35  ? 284 VAL B HG11   1 
ATOM   11682 H HG12   . VAL B 1 284 ? -33.749 -0.288  -20.408 1.00 36.35  ? 284 VAL B HG12   1 
ATOM   11683 H HG13   . VAL B 1 284 ? -33.677 0.424   -18.990 1.00 36.35  ? 284 VAL B HG13   1 
ATOM   11684 H HG21   . VAL B 1 284 ? -34.576 3.152   -19.964 1.00 35.06  ? 284 VAL B HG21   1 
ATOM   11685 H HG22   . VAL B 1 284 ? -33.435 2.900   -18.894 1.00 35.06  ? 284 VAL B HG22   1 
ATOM   11686 H HG23   . VAL B 1 284 ? -33.116 3.719   -20.218 1.00 35.06  ? 284 VAL B HG23   1 
ATOM   11687 N N      . TYR B 1 285 ? -30.382 3.502   -20.818 1.00 24.79  ? 285 TYR B N      1 
ATOM   11688 C CA     . TYR B 1 285 ? -29.703 4.538   -21.608 1.00 26.78  ? 285 TYR B CA     1 
ATOM   11689 C C      . TYR B 1 285 ? -28.187 4.357   -21.722 1.00 28.20  ? 285 TYR B C      1 
ATOM   11690 O O      . TYR B 1 285 ? -27.617 4.623   -22.780 1.00 26.90  ? 285 TYR B O      1 
ATOM   11691 C CB     . TYR B 1 285 ? -29.997 5.930   -21.029 1.00 28.67  ? 285 TYR B CB     1 
ATOM   11692 C CG     . TYR B 1 285 ? -31.396 6.405   -21.338 1.00 29.63  ? 285 TYR B CG     1 
ATOM   11693 C CD1    . TYR B 1 285 ? -31.718 6.897   -22.596 1.00 29.89  ? 285 TYR B CD1    1 
ATOM   11694 C CD2    . TYR B 1 285 ? -32.402 6.339   -20.384 1.00 30.09  ? 285 TYR B CD2    1 
ATOM   11695 C CE1    . TYR B 1 285 ? -33.001 7.323   -22.895 1.00 33.38  ? 285 TYR B CE1    1 
ATOM   11696 C CE2    . TYR B 1 285 ? -33.692 6.761   -20.673 1.00 35.87  ? 285 TYR B CE2    1 
ATOM   11697 C CZ     . TYR B 1 285 ? -33.985 7.253   -21.928 1.00 37.00  ? 285 TYR B CZ     1 
ATOM   11698 O OH     . TYR B 1 285 ? -35.266 7.673   -22.219 1.00 46.22  ? 285 TYR B OH     1 
ATOM   11699 H H      . TYR B 1 285 ? -30.313 3.605   -19.967 1.00 29.75  ? 285 TYR B H      1 
ATOM   11700 H HA     . TYR B 1 285 ? -30.059 4.530   -22.510 1.00 32.13  ? 285 TYR B HA     1 
ATOM   11701 H HB2    . TYR B 1 285 ? -29.897 5.899   -20.065 1.00 34.41  ? 285 TYR B HB2    1 
ATOM   11702 H HB3    . TYR B 1 285 ? -29.373 6.568   -21.408 1.00 34.41  ? 285 TYR B HB3    1 
ATOM   11703 H HD1    . TYR B 1 285 ? -31.058 6.945   -23.249 1.00 35.87  ? 285 TYR B HD1    1 
ATOM   11704 H HD2    . TYR B 1 285 ? -32.208 6.007   -19.537 1.00 36.11  ? 285 TYR B HD2    1 
ATOM   11705 H HE1    . TYR B 1 285 ? -33.199 7.653   -23.741 1.00 40.06  ? 285 TYR B HE1    1 
ATOM   11706 H HE2    . TYR B 1 285 ? -34.355 6.715   -20.023 1.00 43.05  ? 285 TYR B HE2    1 
ATOM   11707 H HH     . TYR B 1 285 ? -35.760 7.576   -21.546 1.00 55.47  ? 285 TYR B HH     1 
ATOM   11708 N N      . GLU B 1 286 ? -27.540 3.922   -20.642 1.00 25.22  ? 286 GLU B N      1 
ATOM   11709 C CA     . GLU B 1 286 ? -26.075 3.910   -20.569 1.00 25.75  ? 286 GLU B CA     1 
ATOM   11710 C C      . GLU B 1 286 ? -25.547 2.489   -20.445 1.00 27.55  ? 286 GLU B C      1 
ATOM   11711 O O      . GLU B 1 286 ? -24.693 2.062   -21.222 1.00 26.63  ? 286 GLU B O      1 
ATOM   11712 C CB     . GLU B 1 286 ? -25.583 4.744   -19.380 1.00 25.95  ? 286 GLU B CB     1 
ATOM   11713 C CG     . GLU B 1 286 ? -25.938 6.225   -19.445 1.00 28.29  ? 286 GLU B CG     1 
ATOM   11714 C CD     . GLU B 1 286 ? -25.159 6.974   -20.512 1.00 33.97  ? 286 GLU B CD     1 
ATOM   11715 O OE1    . GLU B 1 286 ? -25.697 7.962   -21.051 1.00 39.83  ? 286 GLU B OE1    1 
ATOM   11716 O OE2    . GLU B 1 286 ? -24.012 6.578   -20.812 1.00 33.36  ? 286 GLU B OE2    1 
ATOM   11717 H H      . GLU B 1 286 ? -27.927 3.626   -19.933 1.00 30.26  ? 286 GLU B H      1 
ATOM   11718 H HA     . GLU B 1 286 ? -25.703 4.299   -21.374 1.00 30.91  ? 286 GLU B HA     1 
ATOM   11719 H HB2    . GLU B 1 286 ? -25.980 4.385   -18.573 1.00 31.14  ? 286 GLU B HB2    1 
ATOM   11720 H HB3    . GLU B 1 286 ? -24.618 4.670   -19.326 1.00 31.14  ? 286 GLU B HB3    1 
ATOM   11721 H HG2    . GLU B 1 286 ? -26.883 6.315   -19.646 1.00 33.94  ? 286 GLU B HG2    1 
ATOM   11722 H HG3    . GLU B 1 286 ? -25.741 6.634   -18.588 1.00 33.94  ? 286 GLU B HG3    1 
ATOM   11723 N N      . GLY B 1 287 ? -26.064 1.772   -19.451 1.00 22.56  ? 287 GLY B N      1 
ATOM   11724 C CA     . GLY B 1 287 ? -25.635 0.415   -19.146 1.00 23.61  ? 287 GLY B CA     1 
ATOM   11725 C C      . GLY B 1 287 ? -25.922 0.144   -17.680 1.00 25.89  ? 287 GLY B C      1 
ATOM   11726 O O      . GLY B 1 287 ? -26.487 1.000   -17.000 1.00 25.21  ? 287 GLY B O      1 
ATOM   11727 H H      . GLY B 1 287 ? -26.681 2.060   -18.926 1.00 27.07  ? 287 GLY B H      1 
ATOM   11728 H HA2    . GLY B 1 287 ? -26.122 -0.223  -19.691 1.00 28.34  ? 287 GLY B HA2    1 
ATOM   11729 H HA3    . GLY B 1 287 ? -24.684 0.317   -19.309 1.00 28.34  ? 287 GLY B HA3    1 
ATOM   11730 N N      . MET B 1 288 ? -25.548 -1.032  -17.185 1.00 24.84  ? 288 MET B N      1 
ATOM   11731 C CA     . MET B 1 288 ? -25.754 -1.342  -15.769 1.00 26.83  ? 288 MET B CA     1 
ATOM   11732 C C      . MET B 1 288 ? -25.073 -0.291  -14.883 1.00 26.50  ? 288 MET B C      1 
ATOM   11733 O O      . MET B 1 288 ? -24.093 0.324   -15.301 1.00 25.59  ? 288 MET B O      1 
ATOM   11734 C CB     . MET B 1 288 ? -25.224 -2.735  -15.443 1.00 30.46  ? 288 MET B CB     1 
ATOM   11735 C CG     . MET B 1 288 ? -25.975 -3.836  -16.145 1.00 41.39  ? 288 MET B CG     1 
ATOM   11736 S SD     . MET B 1 288 ? -27.740 -3.848  -15.786 1.00 55.57  ? 288 MET B SD     1 
ATOM   11737 C CE     . MET B 1 288 ? -27.665 -4.136  -14.047 1.00 24.10  ? 288 MET B CE     1 
ATOM   11738 H H      . MET B 1 288 ? -25.178 -1.662  -17.639 1.00 29.81  ? 288 MET B H      1 
ATOM   11739 H HA     . MET B 1 288 ? -26.707 -1.333  -15.603 1.00 32.20  ? 288 MET B HA     1 
ATOM   11740 H HB2    . MET B 1 288 ? -24.295 -2.788  -15.716 1.00 36.55  ? 288 MET B HB2    1 
ATOM   11741 H HB3    . MET B 1 288 ? -25.293 -2.883  -14.487 1.00 36.55  ? 288 MET B HB3    1 
ATOM   11742 H HG2    . MET B 1 288 ? -25.866 -3.730  -17.103 1.00 49.67  ? 288 MET B HG2    1 
ATOM   11743 H HG3    . MET B 1 288 ? -25.613 -4.688  -15.857 1.00 49.67  ? 288 MET B HG3    1 
ATOM   11744 H HE1    . MET B 1 288 ? -28.559 -4.323  -13.720 1.00 28.92  ? 288 MET B HE1    1 
ATOM   11745 H HE2    . MET B 1 288 ? -27.086 -4.896  -13.879 1.00 28.92  ? 288 MET B HE2    1 
ATOM   11746 H HE3    . MET B 1 288 ? -27.312 -3.349  -13.610 1.00 28.92  ? 288 MET B HE3    1 
ATOM   11747 N N      . PRO B 1 289 ? -25.598 -0.075  -13.657 1.00 30.40  ? 289 PRO B N      1 
ATOM   11748 C CA     . PRO B 1 289 ? -25.031 0.938   -12.749 1.00 28.16  ? 289 PRO B CA     1 
ATOM   11749 C C      . PRO B 1 289 ? -23.580 0.656   -12.364 1.00 27.75  ? 289 PRO B C      1 
ATOM   11750 O O      . PRO B 1 289 ? -22.900 1.543   -11.840 1.00 22.01  ? 289 PRO B O      1 
ATOM   11751 C CB     . PRO B 1 289 ? -25.933 0.857   -11.508 1.00 31.90  ? 289 PRO B CB     1 
ATOM   11752 C CG     . PRO B 1 289 ? -27.173 0.146   -11.959 1.00 32.05  ? 289 PRO B CG     1 
ATOM   11753 C CD     . PRO B 1 289 ? -26.741 -0.779  -13.048 1.00 28.72  ? 289 PRO B CD     1 
ATOM   11754 H HA     . PRO B 1 289 ? -25.098 1.823   -13.141 1.00 33.79  ? 289 PRO B HA     1 
ATOM   11755 H HB2    . PRO B 1 289 ? -25.484 0.353   -10.811 1.00 38.28  ? 289 PRO B HB2    1 
ATOM   11756 H HB3    . PRO B 1 289 ? -26.145 1.752   -11.200 1.00 38.28  ? 289 PRO B HB3    1 
ATOM   11757 H HG2    . PRO B 1 289 ? -27.549 -0.353  -11.217 1.00 38.46  ? 289 PRO B HG2    1 
ATOM   11758 H HG3    . PRO B 1 289 ? -27.814 0.792   -12.295 1.00 38.46  ? 289 PRO B HG3    1 
ATOM   11759 H HD2    . PRO B 1 289 ? -26.450 -1.623  -12.670 1.00 34.46  ? 289 PRO B HD2    1 
ATOM   11760 H HD3    . PRO B 1 289 ? -27.462 -0.898  -13.684 1.00 34.46  ? 289 PRO B HD3    1 
ATOM   11761 N N      . SER B 1 290 ? -23.128 -0.570  -12.625 1.00 23.17  ? 290 SER B N      1 
ATOM   11762 C CA     . SER B 1 290 ? -21.778 -1.004  -12.295 1.00 20.81  ? 290 SER B CA     1 
ATOM   11763 C C      . SER B 1 290 ? -20.733 -0.657  -13.380 1.00 22.31  ? 290 SER B C      1 
ATOM   11764 O O      . SER B 1 290 ? -19.553 -0.952  -13.211 1.00 22.26  ? 290 SER B O      1 
ATOM   11765 C CB     . SER B 1 290 ? -21.791 -2.517  -12.035 1.00 24.43  ? 290 SER B CB     1 
ATOM   11766 O OG     . SER B 1 290 ? -22.569 -3.184  -13.015 1.00 26.37  ? 290 SER B OG     1 
ATOM   11767 H H      . SER B 1 290 ? -23.598 -1.184  -13.000 1.00 27.80  ? 290 SER B H      1 
ATOM   11768 H HA     . SER B 1 290 ? -21.503 -0.568  -11.473 1.00 24.97  ? 290 SER B HA     1 
ATOM   11769 H HB2    . SER B 1 290 ? -20.882 -2.854  -12.069 1.00 29.31  ? 290 SER B HB2    1 
ATOM   11770 H HB3    . SER B 1 290 ? -22.174 -2.684  -11.160 1.00 29.31  ? 290 SER B HB3    1 
ATOM   11771 H HG     . SER B 1 290 ? -22.249 -3.045  -13.779 1.00 31.65  ? 290 SER B HG     1 
ATOM   11772 N N      . TYR B 1 291 ? -21.145 -0.028  -14.481 1.00 21.87  ? 291 TYR B N      1 
ATOM   11773 C CA     . TYR B 1 291 ? -20.164 0.461   -15.465 1.00 21.90  ? 291 TYR B CA     1 
ATOM   11774 C C      . TYR B 1 291 ? -20.689 1.642   -16.277 1.00 23.61  ? 291 TYR B C      1 
ATOM   11775 O O      . TYR B 1 291 ? -19.896 2.411   -16.823 1.00 21.24  ? 291 TYR B O      1 
ATOM   11776 C CB     . TYR B 1 291 ? -19.719 -0.671  -16.413 1.00 19.21  ? 291 TYR B CB     1 
ATOM   11777 C CG     . TYR B 1 291 ? -20.785 -1.120  -17.380 1.00 20.71  ? 291 TYR B CG     1 
ATOM   11778 C CD1    . TYR B 1 291 ? -20.923 -0.513  -18.620 1.00 19.21  ? 291 TYR B CD1    1 
ATOM   11779 C CD2    . TYR B 1 291 ? -21.653 -2.157  -17.057 1.00 23.69  ? 291 TYR B CD2    1 
ATOM   11780 C CE1    . TYR B 1 291 ? -21.907 -0.916  -19.507 1.00 23.06  ? 291 TYR B CE1    1 
ATOM   11781 C CE2    . TYR B 1 291 ? -22.636 -2.564  -17.935 1.00 24.70  ? 291 TYR B CE2    1 
ATOM   11782 C CZ     . TYR B 1 291 ? -22.757 -1.940  -19.157 1.00 21.67  ? 291 TYR B CZ     1 
ATOM   11783 O OH     . TYR B 1 291 ? -23.731 -2.334  -20.031 1.00 24.36  ? 291 TYR B OH     1 
ATOM   11784 H H      . TYR B 1 291 ? -21.967 0.124   -14.681 1.00 26.25  ? 291 TYR B H      1 
ATOM   11785 H HA     . TYR B 1 291 ? -19.377 0.769   -14.990 1.00 26.28  ? 291 TYR B HA     1 
ATOM   11786 H HB2    . TYR B 1 291 ? -18.960 -0.362  -16.932 1.00 23.06  ? 291 TYR B HB2    1 
ATOM   11787 H HB3    . TYR B 1 291 ? -19.461 -1.440  -15.881 1.00 23.06  ? 291 TYR B HB3    1 
ATOM   11788 H HD1    . TYR B 1 291 ? -20.353 0.183   -18.855 1.00 23.05  ? 291 TYR B HD1    1 
ATOM   11789 H HD2    . TYR B 1 291 ? -21.577 -2.576  -16.230 1.00 28.43  ? 291 TYR B HD2    1 
ATOM   11790 H HE1    . TYR B 1 291 ? -21.993 -0.497  -20.333 1.00 27.67  ? 291 TYR B HE1    1 
ATOM   11791 H HE2    . TYR B 1 291 ? -23.213 -3.255  -17.703 1.00 29.64  ? 291 TYR B HE2    1 
ATOM   11792 H HH     . TYR B 1 291 ? -24.253 -2.874  -19.655 1.00 29.24  ? 291 TYR B HH     1 
ATOM   11793 N N      . GLY B 1 292 ? -22.012 1.782   -16.368 1.00 21.52  ? 292 GLY B N      1 
ATOM   11794 C CA     . GLY B 1 292 ? -22.630 2.995   -16.897 1.00 25.52  ? 292 GLY B CA     1 
ATOM   11795 C C      . GLY B 1 292 ? -22.178 3.454   -18.278 1.00 24.12  ? 292 GLY B C      1 
ATOM   11796 O O      . GLY B 1 292 ? -22.070 4.652   -18.537 1.00 24.14  ? 292 GLY B O      1 
ATOM   11797 H H      . GLY B 1 292 ? -22.579 1.181   -16.130 1.00 25.83  ? 292 GLY B H      1 
ATOM   11798 H HA2    . GLY B 1 292 ? -23.591 2.864   -16.930 1.00 30.62  ? 292 GLY B HA2    1 
ATOM   11799 H HA3    . GLY B 1 292 ? -22.451 3.717   -16.279 1.00 30.62  ? 292 GLY B HA3    1 
ATOM   11800 N N      . GLY B 1 293 ? -21.935 2.507   -19.176 1.00 21.24  ? 293 GLY B N      1 
ATOM   11801 C CA     . GLY B 1 293 ? -21.557 2.837   -20.541 1.00 20.13  ? 293 GLY B CA     1 
ATOM   11802 C C      . GLY B 1 293 ? -20.077 3.138   -20.718 1.00 21.43  ? 293 GLY B C      1 
ATOM   11803 O O      . GLY B 1 293 ? -19.685 3.733   -21.725 1.00 21.23  ? 293 GLY B O      1 
ATOM   11804 H H      . GLY B 1 293 ? -21.993 1.666   -19.020 1.00 25.48  ? 293 GLY B H      1 
ATOM   11805 H HA2    . GLY B 1 293 ? -21.784 2.093   -21.120 1.00 24.15  ? 293 GLY B HA2    1 
ATOM   11806 H HA3    . GLY B 1 293 ? -22.061 3.612   -20.835 1.00 24.15  ? 293 GLY B HA3    1 
ATOM   11807 N N      . LEU B 1 294 ? -19.264 2.717   -19.749 1.00 20.32  ? 294 LEU B N      1 
ATOM   11808 C CA     . LEU B 1 294 ? -17.809 2.867   -19.803 1.00 19.22  ? 294 LEU B CA     1 
ATOM   11809 C C      . LEU B 1 294 ? -17.116 1.520   -19.679 1.00 19.35  ? 294 LEU B C      1 
ATOM   11810 O O      . LEU B 1 294 ? -17.551 0.662   -18.907 1.00 18.76  ? 294 LEU B O      1 
ATOM   11811 C CB     . LEU B 1 294 ? -17.299 3.770   -18.673 1.00 18.75  ? 294 LEU B CB     1 
ATOM   11812 C CG     . LEU B 1 294 ? -17.674 5.246   -18.704 1.00 20.11  ? 294 LEU B CG     1 
ATOM   11813 C CD1    . LEU B 1 294 ? -17.257 5.914   -17.399 1.00 20.15  ? 294 LEU B CD1    1 
ATOM   11814 C CD2    . LEU B 1 294 ? -17.014 5.897   -19.910 1.00 20.46  ? 294 LEU B CD2    1 
ATOM   11815 H H      . LEU B 1 294 ? -19.538 2.331   -19.031 1.00 24.39  ? 294 LEU B H      1 
ATOM   11816 H HA     . LEU B 1 294 ? -17.549 3.255   -20.652 1.00 23.06  ? 294 LEU B HA     1 
ATOM   11817 H HB2    . LEU B 1 294 ? -17.631 3.413   -17.835 1.00 22.50  ? 294 LEU B HB2    1 
ATOM   11818 H HB3    . LEU B 1 294 ? -16.330 3.726   -18.672 1.00 22.50  ? 294 LEU B HB3    1 
ATOM   11819 H HG     . LEU B 1 294 ? -18.636 5.332   -18.798 1.00 24.13  ? 294 LEU B HG     1 
ATOM   11820 H HD11   . LEU B 1 294 ? -17.498 6.853   -17.435 1.00 24.18  ? 294 LEU B HD11   1 
ATOM   11821 H HD12   . LEU B 1 294 ? -17.717 5.482   -16.662 1.00 24.18  ? 294 LEU B HD12   1 
ATOM   11822 H HD13   . LEU B 1 294 ? -16.298 5.822   -17.290 1.00 24.18  ? 294 LEU B HD13   1 
ATOM   11823 H HD21   . LEU B 1 294 ? -17.394 6.779   -20.037 1.00 24.56  ? 294 LEU B HD21   1 
ATOM   11824 H HD22   . LEU B 1 294 ? -16.060 5.967   -19.749 1.00 24.56  ? 294 LEU B HD22   1 
ATOM   11825 H HD23   . LEU B 1 294 ? -17.179 5.360   -20.699 1.00 24.56  ? 294 LEU B HD23   1 
ATOM   11826 N N      . ALA B 1 295 ? -16.025 1.345   -20.419 1.00 17.71  ? 295 ALA B N      1 
ATOM   11827 C CA     . ALA B 1 295 ? -15.114 0.235   -20.172 1.00 15.62  ? 295 ALA B CA     1 
ATOM   11828 C C      . ALA B 1 295 ? -14.519 0.359   -18.770 1.00 15.60  ? 295 ALA B C      1 
ATOM   11829 O O      . ALA B 1 295 ? -14.363 1.467   -18.251 1.00 17.42  ? 295 ALA B O      1 
ATOM   11830 C CB     . ALA B 1 295 ? -14.009 0.209   -21.210 1.00 14.30  ? 295 ALA B CB     1 
ATOM   11831 H H      . ALA B 1 295 ? -15.791 1.856   -21.070 1.00 21.25  ? 295 ALA B H      1 
ATOM   11832 H HA     . ALA B 1 295 ? -15.603 -0.601  -20.224 1.00 18.75  ? 295 ALA B HA     1 
ATOM   11833 H HB1    . ALA B 1 295 ? -13.418 -0.537  -21.023 1.00 17.16  ? 295 ALA B HB1    1 
ATOM   11834 H HB2    . ALA B 1 295 ? -14.405 0.106   -22.089 1.00 17.16  ? 295 ALA B HB2    1 
ATOM   11835 H HB3    . ALA B 1 295 ? -13.514 1.042   -21.165 1.00 17.16  ? 295 ALA B HB3    1 
ATOM   11836 N N      . GLY B 1 296 ? -14.175 -0.777  -18.169 1.00 15.97  ? 296 GLY B N      1 
ATOM   11837 C CA     . GLY B 1 296 ? -13.527 -0.778  -16.874 1.00 15.83  ? 296 GLY B CA     1 
ATOM   11838 C C      . GLY B 1 296 ? -12.306 0.117   -16.850 1.00 15.22  ? 296 GLY B C      1 
ATOM   11839 O O      . GLY B 1 296 ? -12.103 0.903   -15.913 1.00 15.14  ? 296 GLY B O      1 
ATOM   11840 H H      . GLY B 1 296 ? -14.309 -1.561  -18.496 1.00 19.16  ? 296 GLY B H      1 
ATOM   11841 H HA2    . GLY B 1 296 ? -14.151 -0.468  -16.199 1.00 19.00  ? 296 GLY B HA2    1 
ATOM   11842 H HA3    . GLY B 1 296 ? -13.252 -1.681  -16.649 1.00 19.00  ? 296 GLY B HA3    1 
ATOM   11843 N N      . ARG B 1 297 ? -11.482 0.004   -17.882 1.00 15.20  ? 297 ARG B N      1 
ATOM   11844 C CA     . ARG B 1 297 ? -10.240 0.770   -17.939 1.00 16.26  ? 297 ARG B CA     1 
ATOM   11845 C C      . ARG B 1 297 ? -10.491 2.274   -17.903 1.00 14.93  ? 297 ARG B C      1 
ATOM   11846 O O      . ARG B 1 297 ? -9.652  3.021   -17.419 1.00 17.16  ? 297 ARG B O      1 
ATOM   11847 C CB     . ARG B 1 297 ? -9.437  0.406   -19.192 1.00 17.49  ? 297 ARG B CB     1 
ATOM   11848 C CG     . ARG B 1 297 ? -10.223 0.519   -20.481 1.00 15.85  ? 297 ARG B CG     1 
ATOM   11849 C CD     . ARG B 1 297 ? -9.349  0.310   -21.713 1.00 16.48  ? 297 ARG B CD     1 
ATOM   11850 N NE     . ARG B 1 297 ? -10.151 0.457   -22.917 1.00 17.89  ? 297 ARG B NE     1 
ATOM   11851 C CZ     . ARG B 1 297 ? -10.727 -0.553  -23.562 1.00 16.36  ? 297 ARG B CZ     1 
ATOM   11852 N NH1    . ARG B 1 297 ? -10.573 -1.810  -23.143 1.00 17.65  ? 297 ARG B NH1    1 
ATOM   11853 N NH2    . ARG B 1 297 ? -11.456 -0.304  -24.640 1.00 16.39  ? 297 ARG B NH2    1 
ATOM   11854 H H      . ARG B 1 297 ? -11.616 -0.509  -18.559 1.00 18.25  ? 297 ARG B H      1 
ATOM   11855 H HA     . ARG B 1 297 ? -9.700  0.543   -17.166 1.00 19.51  ? 297 ARG B HA     1 
ATOM   11856 H HB2    . ARG B 1 297 ? -8.675  1.002   -19.258 1.00 20.98  ? 297 ARG B HB2    1 
ATOM   11857 H HB3    . ARG B 1 297 ? -9.131  -0.511  -19.111 1.00 20.98  ? 297 ARG B HB3    1 
ATOM   11858 H HG2    . ARG B 1 297 ? -10.919 -0.156  -20.490 1.00 19.03  ? 297 ARG B HG2    1 
ATOM   11859 H HG3    . ARG B 1 297 ? -10.616 1.404   -20.538 1.00 19.03  ? 297 ARG B HG3    1 
ATOM   11860 H HD2    . ARG B 1 297 ? -8.654  0.987   -21.729 1.00 19.77  ? 297 ARG B HD2    1 
ATOM   11861 H HD3    . ARG B 1 297 ? -8.953  -0.574  -21.691 1.00 19.77  ? 297 ARG B HD3    1 
ATOM   11862 H HE     . ARG B 1 297 ? -10.282 1.252   -23.218 1.00 21.47  ? 297 ARG B HE     1 
ATOM   11863 H HH11   . ARG B 1 297 ? -10.108 -1.983  -22.442 1.00 21.18  ? 297 ARG B HH11   1 
ATOM   11864 H HH12   . ARG B 1 297 ? -10.949 -2.452  -23.574 1.00 21.18  ? 297 ARG B HH12   1 
ATOM   11865 H HH21   . ARG B 1 297 ? -11.552 0.505   -24.917 1.00 19.66  ? 297 ARG B HH21   1 
ATOM   11866 H HH22   . ARG B 1 297 ? -11.823 -0.952  -25.070 1.00 19.66  ? 297 ARG B HH22   1 
ATOM   11867 N N      . ASP B 1 298 ? -11.637 2.722   -18.411 1.00 16.74  ? 298 ASP B N      1 
ATOM   11868 C CA     . ASP B 1 298 ? -11.951 4.154   -18.412 1.00 15.54  ? 298 ASP B CA     1 
ATOM   11869 C C      . ASP B 1 298 ? -12.488 4.630   -17.067 1.00 17.19  ? 298 ASP B C      1 
ATOM   11870 O O      . ASP B 1 298 ? -12.243 5.770   -16.666 1.00 15.93  ? 298 ASP B O      1 
ATOM   11871 C CB     . ASP B 1 298 ? -12.931 4.470   -19.523 1.00 16.43  ? 298 ASP B CB     1 
ATOM   11872 C CG     . ASP B 1 298 ? -12.280 4.367   -20.888 1.00 22.18  ? 298 ASP B CG     1 
ATOM   11873 O OD1    . ASP B 1 298 ? -11.249 5.045   -21.099 1.00 25.64  ? 298 ASP B OD1    1 
ATOM   11874 O OD2    . ASP B 1 298 ? -12.769 3.586   -21.725 1.00 21.93  ? 298 ASP B OD2    1 
ATOM   11875 H H      . ASP B 1 298 ? -12.246 2.225   -18.759 1.00 20.08  ? 298 ASP B H      1 
ATOM   11876 H HA     . ASP B 1 298 ? -11.138 4.651   -18.592 1.00 18.65  ? 298 ASP B HA     1 
ATOM   11877 H HB2    . ASP B 1 298 ? -13.667 3.839   -19.489 1.00 19.72  ? 298 ASP B HB2    1 
ATOM   11878 H HB3    . ASP B 1 298 ? -13.260 5.376   -19.411 1.00 19.72  ? 298 ASP B HB3    1 
ATOM   11879 N N      . MET B 1 299 ? -13.198 3.771   -16.346 1.00 15.41  ? 299 MET B N      1 
ATOM   11880 C CA     . MET B 1 299 ? -13.523 4.121   -14.960 1.00 15.80  ? 299 MET B CA     1 
ATOM   11881 C C      . MET B 1 299 ? -12.234 4.288   -14.167 1.00 17.03  ? 299 MET B C      1 
ATOM   11882 O O      . MET B 1 299 ? -12.113 5.193   -13.337 1.00 17.06  ? 299 MET B O      1 
ATOM   11883 C CB     . MET B 1 299 ? -14.417 3.067   -14.311 1.00 16.70  ? 299 MET B CB     1 
ATOM   11884 C CG     . MET B 1 299 ? -15.820 3.065   -14.885 1.00 19.04  ? 299 MET B CG     1 
ATOM   11885 S SD     . MET B 1 299 ? -16.953 1.981   -13.982 1.00 19.54  ? 299 MET B SD     1 
ATOM   11886 C CE     . MET B 1 299 ? -16.483 0.362   -14.603 1.00 18.28  ? 299 MET B CE     1 
ATOM   11887 H H      . MET B 1 299 ? -13.494 3.010   -16.616 1.00 18.49  ? 299 MET B H      1 
ATOM   11888 H HA     . MET B 1 299 ? -14.006 4.962   -14.954 1.00 18.96  ? 299 MET B HA     1 
ATOM   11889 H HB2    . MET B 1 299 ? -14.031 2.190   -14.458 1.00 20.04  ? 299 MET B HB2    1 
ATOM   11890 H HB3    . MET B 1 299 ? -14.481 3.248   -13.360 1.00 20.04  ? 299 MET B HB3    1 
ATOM   11891 H HG2    . MET B 1 299 ? -16.176 3.966   -14.849 1.00 22.85  ? 299 MET B HG2    1 
ATOM   11892 H HG3    . MET B 1 299 ? -15.784 2.760   -15.805 1.00 22.85  ? 299 MET B HG3    1 
ATOM   11893 H HE1    . MET B 1 299 ? -17.040 -0.311  -14.182 1.00 21.94  ? 299 MET B HE1    1 
ATOM   11894 H HE2    . MET B 1 299 ? -16.611 0.344   -15.564 1.00 21.94  ? 299 MET B HE2    1 
ATOM   11895 H HE3    . MET B 1 299 ? -15.550 0.201   -14.390 1.00 21.94  ? 299 MET B HE3    1 
ATOM   11896 N N      . GLU B 1 300 ? -11.265 3.417   -14.429 1.00 14.56  ? 300 GLU B N      1 
ATOM   11897 C CA     . GLU B 1 300 ? -9.981  3.485   -13.741 1.00 18.45  ? 300 GLU B CA     1 
ATOM   11898 C C      . GLU B 1 300 ? -9.222  4.770   -14.067 1.00 14.73  ? 300 GLU B C      1 
ATOM   11899 O O      . GLU B 1 300 ? -8.720  5.454   -13.168 1.00 15.41  ? 300 GLU B O      1 
ATOM   11900 C CB     . GLU B 1 300 ? -9.128  2.270   -14.110 1.00 17.65  ? 300 GLU B CB     1 
ATOM   11901 C CG     . GLU B 1 300 ? -7.826  2.177   -13.334 1.00 15.46  ? 300 GLU B CG     1 
ATOM   11902 C CD     . GLU B 1 300 ? -8.031  1.852   -11.857 1.00 22.15  ? 300 GLU B CD     1 
ATOM   11903 O OE1    . GLU B 1 300 ? -9.083  1.278   -11.498 1.00 19.36  ? 300 GLU B OE1    1 
ATOM   11904 O OE2    . GLU B 1 300 ? -7.132  2.173   -11.057 1.00 24.68  ? 300 GLU B OE2    1 
ATOM   11905 H H      . GLU B 1 300 ? -11.326 2.777   -15.000 1.00 17.48  ? 300 GLU B H      1 
ATOM   11906 H HA     . GLU B 1 300 ? -10.135 3.464   -12.784 1.00 22.14  ? 300 GLU B HA     1 
ATOM   11907 H HB2    . GLU B 1 300 ? -9.639  1.464   -13.940 1.00 21.19  ? 300 GLU B HB2    1 
ATOM   11908 H HB3    . GLU B 1 300 ? -8.905  2.322   -15.052 1.00 21.19  ? 300 GLU B HB3    1 
ATOM   11909 H HG2    . GLU B 1 300 ? -7.283  1.472   -13.719 1.00 18.55  ? 300 GLU B HG2    1 
ATOM   11910 H HG3    . GLU B 1 300 ? -7.354  3.022   -13.392 1.00 18.55  ? 300 GLU B HG3    1 
ATOM   11911 N N      . ALA B 1 301 ? -9.149  5.105   -15.351 1.00 14.22  ? 301 ALA B N      1 
ATOM   11912 C CA     . ALA B 1 301 ? -8.423  6.295   -15.782 1.00 16.38  ? 301 ALA B CA     1 
ATOM   11913 C C      . ALA B 1 301 ? -9.070  7.564   -15.231 1.00 14.74  ? 301 ALA B C      1 
ATOM   11914 O O      . ALA B 1 301 ? -8.379  8.521   -14.866 1.00 12.82  ? 301 ALA B O      1 
ATOM   11915 C CB     . ALA B 1 301 ? -8.355  6.356   -17.296 1.00 15.26  ? 301 ALA B CB     1 
ATOM   11916 H H      . ALA B 1 301 ? -9.511  4.661   -15.992 1.00 17.06  ? 301 ALA B H      1 
ATOM   11917 H HA     . ALA B 1 301 ? -7.515  6.250   -15.443 1.00 19.65  ? 301 ALA B HA     1 
ATOM   11918 H HB1    . ALA B 1 301 ? -7.869  7.154   -17.558 1.00 18.31  ? 301 ALA B HB1    1 
ATOM   11919 H HB2    . ALA B 1 301 ? -7.896  5.566   -17.623 1.00 18.31  ? 301 ALA B HB2    1 
ATOM   11920 H HB3    . ALA B 1 301 ? -9.257  6.386   -17.651 1.00 18.31  ? 301 ALA B HB3    1 
ATOM   11921 N N      . MET B 1 302 ? -10.395 7.569   -15.163 1.00 13.08  ? 302 MET B N      1 
ATOM   11922 C CA     . MET B 1 302 ? -11.119 8.722   -14.635 1.00 14.16  ? 302 MET B CA     1 
ATOM   11923 C C      . MET B 1 302 ? -10.908 8.853   -13.130 1.00 14.19  ? 302 MET B C      1 
ATOM   11924 O O      . MET B 1 302 ? -10.740 9.957   -12.605 1.00 15.53  ? 302 MET B O      1 
ATOM   11925 C CB     . MET B 1 302 ? -12.614 8.617   -14.972 1.00 18.34  ? 302 MET B CB     1 
ATOM   11926 C CG     . MET B 1 302 ? -13.412 9.875   -14.625 1.00 19.03  ? 302 MET B CG     1 
ATOM   11927 S SD     . MET B 1 302 ? -15.032 9.928   -15.424 1.00 18.91  ? 302 MET B SD     1 
ATOM   11928 C CE     . MET B 1 302 ? -15.704 8.338   -14.913 1.00 18.89  ? 302 MET B CE     1 
ATOM   11929 H H      . MET B 1 302 ? -10.899 6.920   -15.415 1.00 15.70  ? 302 MET B H      1 
ATOM   11930 H HA     . MET B 1 302 ? -10.779 9.523   -15.063 1.00 16.99  ? 302 MET B HA     1 
ATOM   11931 H HB2    . MET B 1 302 ? -12.710 8.457   -15.924 1.00 22.00  ? 302 MET B HB2    1 
ATOM   11932 H HB3    . MET B 1 302 ? -12.995 7.877   -14.474 1.00 22.00  ? 302 MET B HB3    1 
ATOM   11933 H HG2    . MET B 1 302 ? -13.551 9.905   -13.665 1.00 22.83  ? 302 MET B HG2    1 
ATOM   11934 H HG3    . MET B 1 302 ? -12.911 10.655  -14.912 1.00 22.83  ? 302 MET B HG3    1 
ATOM   11935 H HE1    . MET B 1 302 ? -16.625 8.276   -15.210 1.00 22.67  ? 302 MET B HE1    1 
ATOM   11936 H HE2    . MET B 1 302 ? -15.179 7.628   -15.315 1.00 22.67  ? 302 MET B HE2    1 
ATOM   11937 H HE3    . MET B 1 302 ? -15.663 8.274   -13.946 1.00 22.67  ? 302 MET B HE3    1 
ATOM   11938 N N      . ALA B 1 303 ? -10.890 7.732   -12.427 1.00 16.14  ? 303 ALA B N      1 
ATOM   11939 C CA     . ALA B 1 303 ? -10.609 7.752   -10.991 1.00 17.99  ? 303 ALA B CA     1 
ATOM   11940 C C      . ALA B 1 303 ? -9.206  8.308   -10.702 1.00 19.44  ? 303 ALA B C      1 
ATOM   11941 O O      . ALA B 1 303 ? -9.020  9.132   -9.803  1.00 18.43  ? 303 ALA B O      1 
ATOM   11942 C CB     . ALA B 1 303 ? -10.743 6.376   -10.429 1.00 17.62  ? 303 ALA B CB     1 
ATOM   11943 H H      . ALA B 1 303 ? -11.036 6.948   -12.750 1.00 19.37  ? 303 ALA B H      1 
ATOM   11944 H HA     . ALA B 1 303 ? -11.257 8.323   -10.549 1.00 21.59  ? 303 ALA B HA     1 
ATOM   11945 H HB1    . ALA B 1 303 ? -10.628 6.414   -9.467  1.00 21.14  ? 303 ALA B HB1    1 
ATOM   11946 H HB2    . ALA B 1 303 ? -11.624 6.033   -10.645 1.00 21.14  ? 303 ALA B HB2    1 
ATOM   11947 H HB3    . ALA B 1 303 ? -10.064 5.807   -10.824 1.00 21.14  ? 303 ALA B HB3    1 
ATOM   11948 N N      . ILE B 1 304 ? -8.220  7.857   -11.469 1.00 15.34  ? 304 ILE B N      1 
ATOM   11949 C CA     . ILE B 1 304 ? -6.846  8.329   -11.312 1.00 14.40  ? 304 ILE B CA     1 
ATOM   11950 C C      . ILE B 1 304 ? -6.733  9.806   -11.709 1.00 16.90  ? 304 ILE B C      1 
ATOM   11951 O O      . ILE B 1 304 ? -6.081  10.608  -11.023 1.00 16.97  ? 304 ILE B O      1 
ATOM   11952 C CB     . ILE B 1 304 ? -5.871  7.465   -12.160 1.00 15.34  ? 304 ILE B CB     1 
ATOM   11953 C CG1    . ILE B 1 304 ? -5.868  6.017   -11.636 1.00 14.63  ? 304 ILE B CG1    1 
ATOM   11954 C CG2    . ILE B 1 304 ? -4.439  8.015   -12.129 1.00 15.02  ? 304 ILE B CG2    1 
ATOM   11955 C CD1    . ILE B 1 304 ? -5.178  5.030   -12.569 1.00 15.48  ? 304 ILE B CD1    1 
ATOM   11956 H H      . ILE B 1 304 ? -8.320  7.273   -12.093 1.00 18.41  ? 304 ILE B H      1 
ATOM   11957 H HA     . ILE B 1 304 ? -6.587  8.247   -10.381 1.00 17.28  ? 304 ILE B HA     1 
ATOM   11958 H HB     . ILE B 1 304 ? -6.181  7.461   -13.079 1.00 18.41  ? 304 ILE B HB     1 
ATOM   11959 H HG12   . ILE B 1 304 ? -5.403  5.994   -10.785 1.00 17.55  ? 304 ILE B HG12   1 
ATOM   11960 H HG13   . ILE B 1 304 ? -6.784  5.722   -11.517 1.00 17.55  ? 304 ILE B HG13   1 
ATOM   11961 H HG21   . ILE B 1 304 ? -3.846  7.384   -12.565 1.00 18.02  ? 304 ILE B HG21   1 
ATOM   11962 H HG22   . ILE B 1 304 ? -4.413  8.864   -12.597 1.00 18.02  ? 304 ILE B HG22   1 
ATOM   11963 H HG23   . ILE B 1 304 ? -4.169  8.137   -11.206 1.00 18.02  ? 304 ILE B HG23   1 
ATOM   11964 H HD11   . ILE B 1 304 ? -5.377  4.127   -12.276 1.00 18.58  ? 304 ILE B HD11   1 
ATOM   11965 H HD12   . ILE B 1 304 ? -5.509  5.165   -13.471 1.00 18.58  ? 304 ILE B HD12   1 
ATOM   11966 H HD13   . ILE B 1 304 ? -4.221  5.183   -12.542 1.00 18.58  ? 304 ILE B HD13   1 
ATOM   11967 N N      . GLY B 1 305 ? -7.375  10.165  -12.818 1.00 14.02  ? 305 GLY B N      1 
ATOM   11968 C CA     . GLY B 1 305 ? -7.298  11.519  -13.339 1.00 15.99  ? 305 GLY B CA     1 
ATOM   11969 C C      . GLY B 1 305 ? -7.896  12.536  -12.384 1.00 16.50  ? 305 GLY B C      1 
ATOM   11970 O O      . GLY B 1 305 ? -7.337  13.615  -12.198 1.00 15.90  ? 305 GLY B O      1 
ATOM   11971 H H      . GLY B 1 305 ? -7.864  9.636   -13.288 1.00 16.82  ? 305 GLY B H      1 
ATOM   11972 H HA2    . GLY B 1 305 ? -6.370  11.753  -13.494 1.00 19.19  ? 305 GLY B HA2    1 
ATOM   11973 H HA3    . GLY B 1 305 ? -7.771  11.564  -14.182 1.00 19.19  ? 305 GLY B HA3    1 
ATOM   11974 N N      . LEU B 1 306 ? -9.028  12.199  -11.770 1.00 16.19  ? 306 LEU B N      1 
ATOM   11975 C CA     . LEU B 1 306 ? -9.680  13.151  -10.870 1.00 18.46  ? 306 LEU B CA     1 
ATOM   11976 C C      . LEU B 1 306 ? -8.763  13.438  -9.689  1.00 18.36  ? 306 LEU B C      1 
ATOM   11977 O O      . LEU B 1 306 ? -8.624  14.583  -9.265  1.00 18.68  ? 306 LEU B O      1 
ATOM   11978 C CB     . LEU B 1 306 ? -11.039 12.626  -10.394 1.00 16.35  ? 306 LEU B CB     1 
ATOM   11979 C CG     . LEU B 1 306 ? -11.789 13.527  -9.405  1.00 22.49  ? 306 LEU B CG     1 
ATOM   11980 C CD1    . LEU B 1 306 ? -11.996 14.936  -9.945  1.00 22.17  ? 306 LEU B CD1    1 
ATOM   11981 C CD2    . LEU B 1 306 ? -13.130 12.903  -9.040  1.00 28.38  ? 306 LEU B CD2    1 
ATOM   11982 H H      . LEU B 1 306 ? -9.432  11.444  -11.853 1.00 19.43  ? 306 LEU B H      1 
ATOM   11983 H HA     . LEU B 1 306 ? -9.828  13.983  -11.346 1.00 22.16  ? 306 LEU B HA     1 
ATOM   11984 H HB2    . LEU B 1 306 ? -11.610 12.507  -11.169 1.00 19.62  ? 306 LEU B HB2    1 
ATOM   11985 H HB3    . LEU B 1 306 ? -10.901 11.770  -9.960  1.00 19.62  ? 306 LEU B HB3    1 
ATOM   11986 H HG     . LEU B 1 306 ? -11.268 13.598  -8.590  1.00 26.99  ? 306 LEU B HG     1 
ATOM   11987 H HD11   . LEU B 1 306 ? -12.551 15.432  -9.324  1.00 26.60  ? 306 LEU B HD11   1 
ATOM   11988 H HD12   . LEU B 1 306 ? -11.134 15.370  -10.037 1.00 26.60  ? 306 LEU B HD12   1 
ATOM   11989 H HD13   . LEU B 1 306 ? -12.434 14.882  -10.809 1.00 26.60  ? 306 LEU B HD13   1 
ATOM   11990 H HD21   . LEU B 1 306 ? -13.588 13.484  -8.413  1.00 34.05  ? 306 LEU B HD21   1 
ATOM   11991 H HD22   . LEU B 1 306 ? -13.660 12.801  -9.846  1.00 34.05  ? 306 LEU B HD22   1 
ATOM   11992 H HD23   . LEU B 1 306 ? -12.974 12.036  -8.634  1.00 34.05  ? 306 LEU B HD23   1 
ATOM   11993 N N      . ARG B 1 307 ? -8.090  12.410  -9.185  1.00 15.89  ? 307 ARG B N      1 
ATOM   11994 C CA     . ARG B 1 307 ? -7.168  12.610  -8.079  1.00 17.29  ? 307 ARG B CA     1 
ATOM   11995 C C      . ARG B 1 307 ? -5.944  13.413  -8.534  1.00 18.03  ? 307 ARG B C      1 
ATOM   11996 O O      . ARG B 1 307 ? -5.440  14.250  -7.783  1.00 18.63  ? 307 ARG B O      1 
ATOM   11997 C CB     . ARG B 1 307 ? -6.760  11.265  -7.480  1.00 20.06  ? 307 ARG B CB     1 
ATOM   11998 C CG     . ARG B 1 307 ? -6.009  11.370  -6.179  1.00 29.83  ? 307 ARG B CG     1 
ATOM   11999 C CD     . ARG B 1 307 ? -5.775  9.992   -5.563  1.00 35.12  ? 307 ARG B CD     1 
ATOM   12000 N NE     . ARG B 1 307 ? -7.022  9.300   -5.226  1.00 31.59  ? 307 ARG B NE     1 
ATOM   12001 C CZ     . ARG B 1 307 ? -7.711  9.501   -4.104  1.00 32.39  ? 307 ARG B CZ     1 
ATOM   12002 N NH1    . ARG B 1 307 ? -7.296  10.389  -3.211  1.00 33.74  ? 307 ARG B NH1    1 
ATOM   12003 N NH2    . ARG B 1 307 ? -8.830  8.824   -3.879  1.00 34.30  ? 307 ARG B NH2    1 
ATOM   12004 H H      . ARG B 1 307 ? -8.149  11.598  -9.462  1.00 19.07  ? 307 ARG B H      1 
ATOM   12005 H HA     . ARG B 1 307 ? -7.616  13.119  -7.385  1.00 20.75  ? 307 ARG B HA     1 
ATOM   12006 H HB2    . ARG B 1 307 ? -7.561  10.742  -7.319  1.00 24.07  ? 307 ARG B HB2    1 
ATOM   12007 H HB3    . ARG B 1 307 ? -6.190  10.803  -8.114  1.00 24.07  ? 307 ARG B HB3    1 
ATOM   12008 H HG2    . ARG B 1 307 ? -5.146  11.783  -6.339  1.00 35.80  ? 307 ARG B HG2    1 
ATOM   12009 H HG3    . ARG B 1 307 ? -6.526  11.900  -5.552  1.00 35.80  ? 307 ARG B HG3    1 
ATOM   12010 H HD2    . ARG B 1 307 ? -5.293  9.442   -6.201  1.00 42.14  ? 307 ARG B HD2    1 
ATOM   12011 H HD3    . ARG B 1 307 ? -5.252  10.090  -4.752  1.00 42.14  ? 307 ARG B HD3    1 
ATOM   12012 H HE     . ARG B 1 307 ? -7.329  8.727   -5.789  1.00 37.91  ? 307 ARG B HE     1 
ATOM   12013 H HH11   . ARG B 1 307 ? -6.573  10.834  -3.344  1.00 40.49  ? 307 ARG B HH11   1 
ATOM   12014 H HH12   . ARG B 1 307 ? -7.749  10.515  -2.491  1.00 40.49  ? 307 ARG B HH12   1 
ATOM   12015 H HH21   . ARG B 1 307 ? -9.108  8.249   -4.455  1.00 41.16  ? 307 ARG B HH21   1 
ATOM   12016 H HH22   . ARG B 1 307 ? -9.277  8.960   -3.157  1.00 41.16  ? 307 ARG B HH22   1 
ATOM   12017 N N      . GLU B 1 308 ? -5.480  13.188  -9.767  1.00 15.65  ? 308 GLU B N      1 
ATOM   12018 C CA     . GLU B 1 308 ? -4.364  13.958  -10.309 1.00 15.63  ? 308 GLU B CA     1 
ATOM   12019 C C      . GLU B 1 308 ? -4.710  15.439  -10.433 1.00 15.81  ? 308 GLU B C      1 
ATOM   12020 O O      . GLU B 1 308 ? -3.854  16.298  -10.262 1.00 16.63  ? 308 GLU B O      1 
ATOM   12021 C CB     . GLU B 1 308 ? -3.938  13.427  -11.683 1.00 17.06  ? 308 GLU B CB     1 
ATOM   12022 C CG     . GLU B 1 308 ? -3.145  12.116  -11.613 1.00 18.55  ? 308 GLU B CG     1 
ATOM   12023 C CD     . GLU B 1 308 ? -2.568  11.686  -12.956 1.00 21.38  ? 308 GLU B CD     1 
ATOM   12024 O OE1    . GLU B 1 308 ? -2.670  12.446  -13.946 1.00 19.53  ? 308 GLU B OE1    1 
ATOM   12025 O OE2    . GLU B 1 308 ? -2.013  10.567  -13.016 1.00 19.07  ? 308 GLU B OE2    1 
ATOM   12026 H H      . GLU B 1 308 ? -5.795  12.596  -10.306 1.00 18.78  ? 308 GLU B H      1 
ATOM   12027 H HA     . GLU B 1 308 ? -3.606  13.877  -9.709  1.00 18.76  ? 308 GLU B HA     1 
ATOM   12028 H HB2    . GLU B 1 308 ? -4.731  13.267  -12.218 1.00 20.47  ? 308 GLU B HB2    1 
ATOM   12029 H HB3    . GLU B 1 308 ? -3.378  14.092  -12.114 1.00 20.47  ? 308 GLU B HB3    1 
ATOM   12030 H HG2    . GLU B 1 308 ? -2.406  12.230  -10.995 1.00 22.25  ? 308 GLU B HG2    1 
ATOM   12031 H HG3    . GLU B 1 308 ? -3.729  11.409  -11.299 1.00 22.25  ? 308 GLU B HG3    1 
ATOM   12032 N N      . ALA B 1 309 ? -5.967  15.720  -10.746 1.00 15.69  ? 309 ALA B N      1 
ATOM   12033 C CA     . ALA B 1 309 ? -6.414  17.086  -10.987 1.00 18.58  ? 309 ALA B CA     1 
ATOM   12034 C C      . ALA B 1 309 ? -6.321  17.940  -9.724  1.00 21.48  ? 309 ALA B C      1 
ATOM   12035 O O      . ALA B 1 309 ? -6.268  19.166  -9.813  1.00 18.87  ? 309 ALA B O      1 
ATOM   12036 C CB     . ALA B 1 309 ? -7.833  17.081  -11.511 1.00 18.10  ? 309 ALA B CB     1 
ATOM   12037 H H      . ALA B 1 309 ? -6.589  15.131  -10.826 1.00 18.83  ? 309 ALA B H      1 
ATOM   12038 H HA     . ALA B 1 309 ? -5.847  17.488  -11.663 1.00 22.30  ? 309 ALA B HA     1 
ATOM   12039 H HB1    . ALA B 1 309 ? -8.113  17.996  -11.671 1.00 21.71  ? 309 ALA B HB1    1 
ATOM   12040 H HB2    . ALA B 1 309 ? -7.862  16.577  -12.339 1.00 21.71  ? 309 ALA B HB2    1 
ATOM   12041 H HB3    . ALA B 1 309 ? -8.411  16.668  -10.851 1.00 21.71  ? 309 ALA B HB3    1 
ATOM   12042 N N      . MET B 1 310 ? -6.305  17.284  -8.565  1.00 19.75  ? 310 MET B N      1 
ATOM   12043 C CA     . MET B 1 310 ? -6.268  17.963  -7.269  1.00 20.74  ? 310 MET B CA     1 
ATOM   12044 C C      . MET B 1 310 ? -4.904  18.584  -6.964  1.00 20.41  ? 310 MET B C      1 
ATOM   12045 O O      . MET B 1 310 ? -4.784  19.363  -6.018  1.00 21.57  ? 310 MET B O      1 
ATOM   12046 C CB     . MET B 1 310 ? -6.614  16.992  -6.119  1.00 20.89  ? 310 MET B CB     1 
ATOM   12047 C CG     . MET B 1 310 ? -7.959  16.259  -6.196  1.00 22.30  ? 310 MET B CG     1 
ATOM   12048 S SD     . MET B 1 310 ? -9.430  17.286  -5.958  1.00 28.19  ? 310 MET B SD     1 
ATOM   12049 C CE     . MET B 1 310 ? -9.727  17.797  -7.634  1.00 27.38  ? 310 MET B CE     1 
ATOM   12050 H H      . MET B 1 310 ? -6.316  16.427  -8.499  1.00 23.70  ? 310 MET B H      1 
ATOM   12051 H HA     . MET B 1 310 ? -6.933  18.669  -7.269  1.00 24.89  ? 310 MET B HA     1 
ATOM   12052 H HB2    . MET B 1 310 ? -5.922  16.313  -6.081  1.00 25.06  ? 310 MET B HB2    1 
ATOM   12053 H HB3    . MET B 1 310 ? -6.612  17.496  -5.290  1.00 25.06  ? 310 MET B HB3    1 
ATOM   12054 H HG2    . MET B 1 310 ? -8.032  15.845  -7.070  1.00 26.76  ? 310 MET B HG2    1 
ATOM   12055 H HG3    . MET B 1 310 ? -7.972  15.572  -5.512  1.00 26.76  ? 310 MET B HG3    1 
ATOM   12056 H HE1    . MET B 1 310 ? -9.045  18.433  -7.898  1.00 32.86  ? 310 MET B HE1    1 
ATOM   12057 H HE2    . MET B 1 310 ? -9.695  17.019  -8.212  1.00 32.86  ? 310 MET B HE2    1 
ATOM   12058 H HE3    . MET B 1 310 ? -10.602 18.212  -7.686  1.00 32.86  ? 310 MET B HE3    1 
ATOM   12059 N N      . GLN B 1 311 ? -3.873  18.218  -7.726  1.00 18.29  ? 311 GLN B N      1 
ATOM   12060 C CA     . GLN B 1 311 ? -2.523  18.700  -7.450  1.00 18.31  ? 311 GLN B CA     1 
ATOM   12061 C C      . GLN B 1 311 ? -2.422  20.180  -7.791  1.00 19.85  ? 311 GLN B C      1 
ATOM   12062 O O      . GLN B 1 311 ? -2.662  20.580  -8.928  1.00 17.17  ? 311 GLN B O      1 
ATOM   12063 C CB     . GLN B 1 311 ? -1.464  17.904  -8.235  1.00 19.10  ? 311 GLN B CB     1 
ATOM   12064 C CG     . GLN B 1 311 ? -0.025  18.401  -7.994  1.00 24.09  ? 311 GLN B CG     1 
ATOM   12065 C CD     . GLN B 1 311 ? 1.018   17.785  -8.932  1.00 32.51  ? 311 GLN B CD     1 
ATOM   12066 O OE1    . GLN B 1 311 ? 0.695   17.289  -10.008 1.00 32.26  ? 311 GLN B OE1    1 
ATOM   12067 N NE2    . GLN B 1 311 ? 2.285   17.837  -8.522  1.00 34.83  ? 311 GLN B NE2    1 
ATOM   12068 H H      . GLN B 1 311 ? -3.928  17.694  -8.405  1.00 21.95  ? 311 GLN B H      1 
ATOM   12069 H HA     . GLN B 1 311 ? -2.336  18.596  -6.504  1.00 21.97  ? 311 GLN B HA     1 
ATOM   12070 H HB2    . GLN B 1 311 ? -1.508  16.973  -7.967  1.00 22.92  ? 311 GLN B HB2    1 
ATOM   12071 H HB3    . GLN B 1 311 ? -1.652  17.984  -9.183  1.00 22.92  ? 311 GLN B HB3    1 
ATOM   12072 H HG2    . GLN B 1 311 ? 0.009   19.361  -8.120  1.00 28.91  ? 311 GLN B HG2    1 
ATOM   12073 H HG3    . GLN B 1 311 ? 0.231   18.181  -7.085  1.00 28.91  ? 311 GLN B HG3    1 
ATOM   12074 H HE21   . GLN B 1 311 ? 2.478   18.202  -7.768  1.00 41.80  ? 311 GLN B HE21   1 
ATOM   12075 H HE22   . GLN B 1 311 ? 2.909   17.505  -9.012  1.00 41.80  ? 311 GLN B HE22   1 
ATOM   12076 N N      . PHE B 1 312 ? -2.046  20.989  -6.806  1.00 17.34  ? 312 PHE B N      1 
ATOM   12077 C CA     . PHE B 1 312 ? -2.047  22.429  -6.995  1.00 15.87  ? 312 PHE B CA     1 
ATOM   12078 C C      . PHE B 1 312 ? -1.237  22.850  -8.220  1.00 16.54  ? 312 PHE B C      1 
ATOM   12079 O O      . PHE B 1 312 ? -1.717  23.619  -9.061  1.00 17.71  ? 312 PHE B O      1 
ATOM   12080 C CB     . PHE B 1 312 ? -1.497  23.153  -5.764  1.00 18.72  ? 312 PHE B CB     1 
ATOM   12081 C CG     . PHE B 1 312 ? -1.317  24.618  -5.993  1.00 20.00  ? 312 PHE B CG     1 
ATOM   12082 C CD1    . PHE B 1 312 ? -2.417  25.441  -6.067  1.00 18.96  ? 312 PHE B CD1    1 
ATOM   12083 C CD2    . PHE B 1 312 ? -0.061  25.158  -6.187  1.00 20.72  ? 312 PHE B CD2    1 
ATOM   12084 C CE1    . PHE B 1 312 ? -2.274  26.785  -6.305  1.00 20.53  ? 312 PHE B CE1    1 
ATOM   12085 C CE2    . PHE B 1 312 ? 0.092   26.511  -6.426  1.00 23.76  ? 312 PHE B CE2    1 
ATOM   12086 C CZ     . PHE B 1 312 ? -1.020  27.323  -6.488  1.00 19.08  ? 312 PHE B CZ     1 
ATOM   12087 H H      . PHE B 1 312 ? -1.789  20.730  -6.027  1.00 20.81  ? 312 PHE B H      1 
ATOM   12088 H HA     . PHE B 1 312 ? -2.961  22.725  -7.129  1.00 19.04  ? 312 PHE B HA     1 
ATOM   12089 H HB2    . PHE B 1 312 ? -2.115  23.039  -5.027  1.00 22.47  ? 312 PHE B HB2    1 
ATOM   12090 H HB3    . PHE B 1 312 ? -0.633  22.776  -5.535  1.00 22.47  ? 312 PHE B HB3    1 
ATOM   12091 H HD1    . PHE B 1 312 ? -3.267  25.083  -5.948  1.00 22.75  ? 312 PHE B HD1    1 
ATOM   12092 H HD2    . PHE B 1 312 ? 0.688   24.609  -6.149  1.00 24.87  ? 312 PHE B HD2    1 
ATOM   12093 H HE1    . PHE B 1 312 ? -3.025  27.333  -6.343  1.00 24.64  ? 312 PHE B HE1    1 
ATOM   12094 H HE2    . PHE B 1 312 ? 0.941   26.871  -6.547  1.00 28.51  ? 312 PHE B HE2    1 
ATOM   12095 H HZ     . PHE B 1 312 ? -0.923  28.235  -6.643  1.00 22.89  ? 312 PHE B HZ     1 
ATOM   12096 N N      . GLU B 1 313 ? -0.014  22.346  -8.331  1.00 16.03  ? 313 GLU B N      1 
ATOM   12097 C CA     . GLU B 1 313 ? 0.878   22.790  -9.407  1.00 19.66  ? 313 GLU B CA     1 
ATOM   12098 C C      . GLU B 1 313 ? 0.297   22.466  -10.782 1.00 17.91  ? 313 GLU B C      1 
ATOM   12099 O O      . GLU B 1 313 ? 0.466   23.247  -11.728 1.00 14.94  ? 313 GLU B O      1 
ATOM   12100 C CB     . GLU B 1 313 ? 2.255   22.162  -9.255  1.00 22.56  ? 313 GLU B CB     1 
ATOM   12101 C CG     . GLU B 1 313 ? 3.023   22.671  -8.048  1.00 25.44  ? 313 GLU B CG     1 
ATOM   12102 C CD     . GLU B 1 313 ? 2.641   21.979  -6.746  1.00 29.88  ? 313 GLU B CD     1 
ATOM   12103 O OE1    . GLU B 1 313 ? 1.889   20.976  -6.771  1.00 24.67  ? 313 GLU B OE1    1 
ATOM   12104 O OE2    . GLU B 1 313 ? 3.102   22.456  -5.689  1.00 34.97  ? 313 GLU B OE2    1 
ATOM   12105 H H      . GLU B 1 313 ? 0.322   21.752  -7.808  1.00 19.23  ? 313 GLU B H      1 
ATOM   12106 H HA     . GLU B 1 313 ? 0.983   23.753  -9.349  1.00 23.60  ? 313 GLU B HA     1 
ATOM   12107 H HB2    . GLU B 1 313 ? 2.159   21.200  -9.177  1.00 27.07  ? 313 GLU B HB2    1 
ATOM   12108 H HB3    . GLU B 1 313 ? 2.778   22.373  -10.044 1.00 27.07  ? 313 GLU B HB3    1 
ATOM   12109 H HG2    . GLU B 1 313 ? 3.971   22.525  -8.195  1.00 30.53  ? 313 GLU B HG2    1 
ATOM   12110 H HG3    . GLU B 1 313 ? 2.849   23.619  -7.943  1.00 30.53  ? 313 GLU B HG3    1 
ATOM   12111 N N      . TYR B 1 314 ? -0.399  21.336  -10.894 1.00 15.29  ? 314 TYR B N      1 
ATOM   12112 C CA     . TYR B 1 314 ? -1.032  20.977  -12.161 1.00 16.45  ? 314 TYR B CA     1 
ATOM   12113 C C      . TYR B 1 314 ? -2.097  22.024  -12.527 1.00 17.96  ? 314 TYR B C      1 
ATOM   12114 O O      . TYR B 1 314 ? -2.079  22.572  -13.628 1.00 16.51  ? 314 TYR B O      1 
ATOM   12115 C CB     . TYR B 1 314 ? -1.670  19.566  -12.135 1.00 15.93  ? 314 TYR B CB     1 
ATOM   12116 C CG     . TYR B 1 314 ? -2.841  19.539  -13.074 1.00 14.29  ? 314 TYR B CG     1 
ATOM   12117 C CD1    . TYR B 1 314 ? -2.647  19.559  -14.452 1.00 17.00  ? 314 TYR B CD1    1 
ATOM   12118 C CD2    . TYR B 1 314 ? -4.139  19.614  -12.594 1.00 15.41  ? 314 TYR B CD2    1 
ATOM   12119 C CE1    . TYR B 1 314 ? -3.705  19.606  -15.313 1.00 18.08  ? 314 TYR B CE1    1 
ATOM   12120 C CE2    . TYR B 1 314 ? -5.211  19.664  -13.454 1.00 13.87  ? 314 TYR B CE2    1 
ATOM   12121 C CZ     . TYR B 1 314 ? -4.986  19.671  -14.813 1.00 16.64  ? 314 TYR B CZ     1 
ATOM   12122 O OH     . TYR B 1 314 ? -6.056  19.732  -15.672 1.00 21.10  ? 314 TYR B OH     1 
ATOM   12123 H H      . TYR B 1 314 ? -0.519  20.767  -10.260 1.00 18.35  ? 314 TYR B H      1 
ATOM   12124 H HA     . TYR B 1 314 ? -0.358  20.983  -12.859 1.00 19.74  ? 314 TYR B HA     1 
ATOM   12125 H HB2    . TYR B 1 314 ? -1.021  18.907  -12.428 1.00 19.11  ? 314 TYR B HB2    1 
ATOM   12126 H HB3    . TYR B 1 314 ? -1.984  19.365  -11.240 1.00 19.11  ? 314 TYR B HB3    1 
ATOM   12127 H HD1    . TYR B 1 314 ? -1.782  19.532  -14.792 1.00 20.40  ? 314 TYR B HD1    1 
ATOM   12128 H HD2    . TYR B 1 314 ? -4.288  19.626  -11.676 1.00 18.50  ? 314 TYR B HD2    1 
ATOM   12129 H HE1    . TYR B 1 314 ? -3.561  19.611  -16.232 1.00 21.70  ? 314 TYR B HE1    1 
ATOM   12130 H HE2    . TYR B 1 314 ? -6.078  19.706  -13.121 1.00 16.65  ? 314 TYR B HE2    1 
ATOM   12131 H HH     . TYR B 1 314 ? -6.772  19.780  -15.236 1.00 25.32  ? 314 TYR B HH     1 
ATOM   12132 N N      . ILE B 1 315 ? -3.033  22.319  -11.629 1.00 16.15  ? 315 ILE B N      1 
ATOM   12133 C CA     . ILE B 1 315 ? -4.166  23.151  -12.056 1.00 13.60  ? 315 ILE B CA     1 
ATOM   12134 C C      . ILE B 1 315 ? -3.728  24.612  -12.167 1.00 17.79  ? 315 ILE B C      1 
ATOM   12135 O O      . ILE B 1 315 ? -4.239  25.361  -13.015 1.00 14.75  ? 315 ILE B O      1 
ATOM   12136 C CB     . ILE B 1 315 ? -5.396  22.980  -11.112 1.00 15.59  ? 315 ILE B CB     1 
ATOM   12137 C CG1    . ILE B 1 315 ? -6.630  23.665  -11.704 1.00 14.35  ? 315 ILE B CG1    1 
ATOM   12138 C CG2    . ILE B 1 315 ? -5.092  23.467  -9.696  1.00 16.74  ? 315 ILE B CG2    1 
ATOM   12139 C CD1    . ILE B 1 315 ? -7.157  23.021  -12.951 1.00 20.85  ? 315 ILE B CD1    1 
ATOM   12140 H H      . ILE B 1 315 ? -3.043  22.067  -10.807 1.00 19.38  ? 315 ILE B H      1 
ATOM   12141 H HA     . ILE B 1 315 ? -4.441  22.863  -12.940 1.00 16.32  ? 315 ILE B HA     1 
ATOM   12142 H HB     . ILE B 1 315 ? -5.590  22.031  -11.057 1.00 18.70  ? 315 ILE B HB     1 
ATOM   12143 H HG12   . ILE B 1 315 ? -7.339  23.648  -11.043 1.00 17.22  ? 315 ILE B HG12   1 
ATOM   12144 H HG13   . ILE B 1 315 ? -6.409  24.585  -11.917 1.00 17.22  ? 315 ILE B HG13   1 
ATOM   12145 H HG21   . ILE B 1 315 ? -5.853  23.274  -9.127  1.00 20.08  ? 315 ILE B HG21   1 
ATOM   12146 H HG22   . ILE B 1 315 ? -4.306  23.005  -9.365  1.00 20.08  ? 315 ILE B HG22   1 
ATOM   12147 H HG23   . ILE B 1 315 ? -4.929  24.423  -9.717  1.00 20.08  ? 315 ILE B HG23   1 
ATOM   12148 H HD11   . ILE B 1 315 ? -8.020  23.409  -13.164 1.00 25.02  ? 315 ILE B HD11   1 
ATOM   12149 H HD12   . ILE B 1 315 ? -6.536  23.181  -13.678 1.00 25.02  ? 315 ILE B HD12   1 
ATOM   12150 H HD13   . ILE B 1 315 ? -7.252  22.068  -12.798 1.00 25.02  ? 315 ILE B HD13   1 
ATOM   12151 N N      . GLU B 1 316 ? -2.754  25.005  -11.349 1.00 16.18  ? 316 GLU B N      1 
ATOM   12152 C CA     . GLU B 1 316 ? -2.154  26.327  -11.464 1.00 19.16  ? 316 GLU B CA     1 
ATOM   12153 C C      . GLU B 1 316 ? -1.551  26.501  -12.854 1.00 17.71  ? 316 GLU B C      1 
ATOM   12154 O O      . GLU B 1 316 ? -1.790  27.506  -13.530 1.00 16.05  ? 316 GLU B O      1 
ATOM   12155 C CB     . GLU B 1 316 ? -1.074  26.539  -10.399 1.00 18.50  ? 316 GLU B CB     1 
ATOM   12156 C CG     . GLU B 1 316 ? -0.404  27.898  -10.495 1.00 16.43  ? 316 GLU B CG     1 
ATOM   12157 C CD     . GLU B 1 316 ? 0.936   28.001  -9.765  1.00 21.58  ? 316 GLU B CD     1 
ATOM   12158 O OE1    . GLU B 1 316 ? 1.654   26.990  -9.627  1.00 18.72  ? 316 GLU B OE1    1 
ATOM   12159 O OE2    . GLU B 1 316 ? 1.277   29.119  -9.341  1.00 25.11  ? 316 GLU B OE2    1 
ATOM   12160 H H      . GLU B 1 316 ? -2.424  24.523  -10.718 1.00 19.42  ? 316 GLU B H      1 
ATOM   12161 H HA     . GLU B 1 316 ? -2.839  27.002  -11.342 1.00 22.99  ? 316 GLU B HA     1 
ATOM   12162 H HB2    . GLU B 1 316 ? -1.479  26.467  -9.521  1.00 22.19  ? 316 GLU B HB2    1 
ATOM   12163 H HB3    . GLU B 1 316 ? -0.393  25.857  -10.507 1.00 22.19  ? 316 GLU B HB3    1 
ATOM   12164 H HG2    . GLU B 1 316 ? -0.237  28.116  -11.423 1.00 19.71  ? 316 GLU B HG2    1 
ATOM   12165 H HG3    . GLU B 1 316 ? -0.998  28.561  -10.109 1.00 19.71  ? 316 GLU B HG3    1 
ATOM   12166 N N      . HIS B 1 317 ? -0.754  25.527  -13.284 1.00 14.65  ? 317 HIS B N      1 
ATOM   12167 C CA     . HIS B 1 317 ? -0.143  25.630  -14.600 1.00 14.98  ? 317 HIS B CA     1 
ATOM   12168 C C      . HIS B 1 317 ? -1.209  25.609  -15.693 1.00 16.39  ? 317 HIS B C      1 
ATOM   12169 O O      . HIS B 1 317 ? -1.114  26.360  -16.667 1.00 14.35  ? 317 HIS B O      1 
ATOM   12170 C CB     . HIS B 1 317 ? 0.874   24.515  -14.847 1.00 16.97  ? 317 HIS B CB     1 
ATOM   12171 C CG     . HIS B 1 317 ? 1.278   24.415  -16.284 1.00 16.83  ? 317 HIS B CG     1 
ATOM   12172 N ND1    . HIS B 1 317 ? 0.661   23.560  -17.164 1.00 18.65  ? 317 HIS B ND1    1 
ATOM   12173 C CD2    . HIS B 1 317 ? 2.179   25.124  -17.008 1.00 16.79  ? 317 HIS B CD2    1 
ATOM   12174 C CE1    . HIS B 1 317 ? 1.186   23.719  -18.371 1.00 18.92  ? 317 HIS B CE1    1 
ATOM   12175 N NE2    . HIS B 1 317 ? 2.106   24.663  -18.303 1.00 16.64  ? 317 HIS B NE2    1 
ATOM   12176 H H      . HIS B 1 317 ? -0.556  24.815  -12.845 1.00 17.58  ? 317 HIS B H      1 
ATOM   12177 H HA     . HIS B 1 317 ? 0.327   26.477  -14.661 1.00 17.97  ? 317 HIS B HA     1 
ATOM   12178 H HB2    . HIS B 1 317 ? 1.671   24.691  -14.322 1.00 20.37  ? 317 HIS B HB2    1 
ATOM   12179 H HB3    . HIS B 1 317 ? 0.484   23.667  -14.585 1.00 20.37  ? 317 HIS B HB3    1 
ATOM   12180 H HD1    . HIS B 1 317 ? 0.038   23.003  -16.962 1.00 22.38  ? 317 HIS B HD1    1 
ATOM   12181 H HD2    . HIS B 1 317 ? 2.746   25.788  -16.688 1.00 20.15  ? 317 HIS B HD2    1 
ATOM   12182 H HE1    . HIS B 1 317 ? 0.949   23.244  -19.134 1.00 22.70  ? 317 HIS B HE1    1 
ATOM   12183 N N      . ARG B 1 318 ? -2.227  24.767  -15.526 1.00 14.04  ? 318 ARG B N      1 
ATOM   12184 C CA     . ARG B 1 318 ? -3.276  24.635  -16.539 1.00 17.26  ? 318 ARG B CA     1 
ATOM   12185 C C      . ARG B 1 318 ? -3.908  26.004  -16.801 1.00 15.51  ? 318 ARG B C      1 
ATOM   12186 O O      . ARG B 1 318 ? -3.966  26.478  -17.939 1.00 15.74  ? 318 ARG B O      1 
ATOM   12187 C CB     . ARG B 1 318 ? -4.339  23.620  -16.088 1.00 14.87  ? 318 ARG B CB     1 
ATOM   12188 C CG     . ARG B 1 318 ? -5.384  23.209  -17.156 1.00 14.08  ? 318 ARG B CG     1 
ATOM   12189 C CD     . ARG B 1 318 ? -6.421  24.291  -17.390 1.00 15.86  ? 318 ARG B CD     1 
ATOM   12190 N NE     . ARG B 1 318 ? -7.600  23.869  -18.149 1.00 15.63  ? 318 ARG B NE     1 
ATOM   12191 C CZ     . ARG B 1 318 ? -7.616  23.649  -19.464 1.00 16.70  ? 318 ARG B CZ     1 
ATOM   12192 N NH1    . ARG B 1 318 ? -6.499  23.738  -20.178 1.00 15.56  ? 318 ARG B NH1    1 
ATOM   12193 N NH2    . ARG B 1 318 ? -8.745  23.296  -20.063 1.00 15.65  ? 318 ARG B NH2    1 
ATOM   12194 H H      . ARG B 1 318 ? -2.335  24.262  -14.838 1.00 16.85  ? 318 ARG B H      1 
ATOM   12195 H HA     . ARG B 1 318 ? -2.884  24.317  -17.367 1.00 20.71  ? 318 ARG B HA     1 
ATOM   12196 H HB2    . ARG B 1 318 ? -3.886  22.812  -15.801 1.00 17.85  ? 318 ARG B HB2    1 
ATOM   12197 H HB3    . ARG B 1 318 ? -4.825  23.999  -15.339 1.00 17.85  ? 318 ARG B HB3    1 
ATOM   12198 H HG2    . ARG B 1 318 ? -4.930  23.039  -17.996 1.00 16.90  ? 318 ARG B HG2    1 
ATOM   12199 H HG3    . ARG B 1 318 ? -5.845  22.409  -16.858 1.00 16.90  ? 318 ARG B HG3    1 
ATOM   12200 H HD2    . ARG B 1 318 ? -6.726  24.623  -16.531 1.00 19.03  ? 318 ARG B HD2    1 
ATOM   12201 H HD3    . ARG B 1 318 ? -6.014  25.010  -17.893 1.00 19.03  ? 318 ARG B HD3    1 
ATOM   12202 H HE     . ARG B 1 318 ? -8.334  23.755  -17.716 1.00 18.75  ? 318 ARG B HE     1 
ATOM   12203 H HH11   . ARG B 1 318 ? -5.762  23.971  -19.801 1.00 18.67  ? 318 ARG B HH11   1 
ATOM   12204 H HH12   . ARG B 1 318 ? -6.518  23.584  -21.024 1.00 18.67  ? 318 ARG B HH12   1 
ATOM   12205 H HH21   . ARG B 1 318 ? -9.469  23.222  -19.606 1.00 18.79  ? 318 ARG B HH21   1 
ATOM   12206 H HH22   . ARG B 1 318 ? -8.751  23.132  -20.907 1.00 18.79  ? 318 ARG B HH22   1 
ATOM   12207 N N      . VAL B 1 319 ? -4.363  26.641  -15.732 1.00 15.38  ? 319 VAL B N      1 
ATOM   12208 C CA     . VAL B 1 319 ? -5.061  27.914  -15.832 1.00 16.18  ? 319 VAL B CA     1 
ATOM   12209 C C      . VAL B 1 319 ? -4.116  29.036  -16.265 1.00 13.83  ? 319 VAL B C      1 
ATOM   12210 O O      . VAL B 1 319 ? -4.501  29.895  -17.052 1.00 16.22  ? 319 VAL B O      1 
ATOM   12211 C CB     . VAL B 1 319 ? -5.754  28.262  -14.486 1.00 15.67  ? 319 VAL B CB     1 
ATOM   12212 C CG1    . VAL B 1 319 ? -6.331  29.667  -14.503 1.00 18.85  ? 319 VAL B CG1    1 
ATOM   12213 C CG2    . VAL B 1 319 ? -6.867  27.254  -14.196 1.00 15.39  ? 319 VAL B CG2    1 
ATOM   12214 H H      . VAL B 1 319 ? -4.279  26.353  -14.926 1.00 18.45  ? 319 VAL B H      1 
ATOM   12215 H HA     . VAL B 1 319 ? -5.753  27.836  -16.507 1.00 19.41  ? 319 VAL B HA     1 
ATOM   12216 H HB     . VAL B 1 319 ? -5.103  28.210  -13.769 1.00 18.80  ? 319 VAL B HB     1 
ATOM   12217 H HG11   . VAL B 1 319 ? -6.945  29.763  -13.758 1.00 22.63  ? 319 VAL B HG11   1 
ATOM   12218 H HG12   . VAL B 1 319 ? -5.609  30.310  -14.419 1.00 22.63  ? 319 VAL B HG12   1 
ATOM   12219 H HG13   . VAL B 1 319 ? -6.804  29.803  -15.339 1.00 22.63  ? 319 VAL B HG13   1 
ATOM   12220 H HG21   . VAL B 1 319 ? -7.289  27.484  -13.353 1.00 18.46  ? 319 VAL B HG21   1 
ATOM   12221 H HG22   . VAL B 1 319 ? -7.519  27.289  -14.913 1.00 18.46  ? 319 VAL B HG22   1 
ATOM   12222 H HG23   . VAL B 1 319 ? -6.482  26.365  -14.142 1.00 18.46  ? 319 VAL B HG23   1 
ATOM   12223 N N      . LYS B 1 320 ? -2.872  29.029  -15.789 1.00 13.93  ? 320 LYS B N      1 
ATOM   12224 C CA     . LYS B 1 320 ? -1.953  30.103  -16.164 1.00 16.92  ? 320 LYS B CA     1 
ATOM   12225 C C      . LYS B 1 320 ? -1.480  29.981  -17.620 1.00 18.70  ? 320 LYS B C      1 
ATOM   12226 O O      . LYS B 1 320 ? -1.135  30.981  -18.240 1.00 16.40  ? 320 LYS B O      1 
ATOM   12227 C CB     . LYS B 1 320 ? -0.762  30.154  -15.209 1.00 16.75  ? 320 LYS B CB     1 
ATOM   12228 C CG     . LYS B 1 320 ? -1.147  30.833  -13.904 1.00 19.32  ? 320 LYS B CG     1 
ATOM   12229 C CD     . LYS B 1 320 ? -0.024  30.890  -12.918 1.00 22.10  ? 320 LYS B CD     1 
ATOM   12230 C CE     . LYS B 1 320 ? -0.464  31.675  -11.696 1.00 25.96  ? 320 LYS B CE     1 
ATOM   12231 N NZ     . LYS B 1 320 ? 0.496   31.557  -10.579 1.00 30.38  ? 320 LYS B NZ     1 
ATOM   12232 H H      . LYS B 1 320 ? -2.543  28.433  -15.263 1.00 16.72  ? 320 LYS B H      1 
ATOM   12233 H HA     . LYS B 1 320 ? -2.421  30.949  -16.082 1.00 20.31  ? 320 LYS B HA     1 
ATOM   12234 H HB2    . LYS B 1 320 ? -0.469  29.251  -15.010 1.00 20.10  ? 320 LYS B HB2    1 
ATOM   12235 H HB3    . LYS B 1 320 ? -0.043  30.661  -15.617 1.00 20.10  ? 320 LYS B HB3    1 
ATOM   12236 H HG2    . LYS B 1 320 ? -1.425  31.743  -14.093 1.00 23.18  ? 320 LYS B HG2    1 
ATOM   12237 H HG3    . LYS B 1 320 ? -1.877  30.341  -13.497 1.00 23.18  ? 320 LYS B HG3    1 
ATOM   12238 H HD2    . LYS B 1 320 ? 0.206   29.990  -12.639 1.00 26.52  ? 320 LYS B HD2    1 
ATOM   12239 H HD3    . LYS B 1 320 ? 0.743   31.327  -13.311 1.00 26.52  ? 320 LYS B HD3    1 
ATOM   12240 H HE2    . LYS B 1 320 ? -0.538  32.613  -11.932 1.00 31.15  ? 320 LYS B HE2    1 
ATOM   12241 H HE3    . LYS B 1 320 ? -1.321  31.339  -11.397 1.00 31.15  ? 320 LYS B HE3    1 
ATOM   12242 H HZ1    . LYS B 1 320 ? 0.209   32.028  -9.880  1.00 36.46  ? 320 LYS B HZ1    1 
ATOM   12243 H HZ2    . LYS B 1 320 ? 0.579   30.704  -10.339 1.00 36.46  ? 320 LYS B HZ2    1 
ATOM   12244 H HZ3    . LYS B 1 320 ? 1.292   31.866  -10.829 1.00 36.46  ? 320 LYS B HZ3    1 
ATOM   12245 N N      . GLN B 1 321 ? -1.491  28.774  -18.174 1.00 15.16  ? 321 GLN B N      1 
ATOM   12246 C CA     . GLN B 1 321 ? -1.181  28.601  -19.594 1.00 16.05  ? 321 GLN B CA     1 
ATOM   12247 C C      . GLN B 1 321 ? -2.239  29.282  -20.470 1.00 16.75  ? 321 GLN B C      1 
ATOM   12248 O O      . GLN B 1 321 ? -1.911  29.957  -21.447 1.00 16.95  ? 321 GLN B O      1 
ATOM   12249 C CB     . GLN B 1 321 ? -1.088  27.115  -19.953 1.00 16.64  ? 321 GLN B CB     1 
ATOM   12250 C CG     . GLN B 1 321 ? -0.681  26.864  -21.391 1.00 19.97  ? 321 GLN B CG     1 
ATOM   12251 C CD     . GLN B 1 321 ? -0.665  25.385  -21.743 1.00 18.66  ? 321 GLN B CD     1 
ATOM   12252 O OE1    . GLN B 1 321 ? -1.720  24.757  -21.855 1.00 16.44  ? 321 GLN B OE1    1 
ATOM   12253 N NE2    . GLN B 1 321 ? 0.534   24.820  -21.909 1.00 20.05  ? 321 GLN B NE2    1 
ATOM   12254 H H      . GLN B 1 321 ? -1.672  28.044  -17.757 1.00 18.20  ? 321 GLN B H      1 
ATOM   12255 H HA     . GLN B 1 321 ? -0.323  29.011  -19.784 1.00 19.26  ? 321 GLN B HA     1 
ATOM   12256 H HB2    . GLN B 1 321 ? -0.428  26.695  -19.380 1.00 19.97  ? 321 GLN B HB2    1 
ATOM   12257 H HB3    . GLN B 1 321 ? -1.955  26.704  -19.813 1.00 19.97  ? 321 GLN B HB3    1 
ATOM   12258 H HG2    . GLN B 1 321 ? -1.310  27.303  -21.984 1.00 23.97  ? 321 GLN B HG2    1 
ATOM   12259 H HG3    . GLN B 1 321 ? 0.211   27.216  -21.533 1.00 23.97  ? 321 GLN B HG3    1 
ATOM   12260 H HE21   . GLN B 1 321 ? 1.248   25.290  -21.815 1.00 24.06  ? 321 GLN B HE21   1 
ATOM   12261 H HE22   . GLN B 1 321 ? 0.592   23.986  -22.109 1.00 24.06  ? 321 GLN B HE22   1 
ATOM   12262 N N      . VAL B 1 322 ? -3.507  29.075  -20.126 1.00 15.86  ? 322 VAL B N      1 
ATOM   12263 C CA     . VAL B 1 322 ? -4.616  29.715  -20.820 1.00 14.51  ? 322 VAL B CA     1 
ATOM   12264 C C      . VAL B 1 322 ? -4.480  31.230  -20.659 1.00 18.47  ? 322 VAL B C      1 
ATOM   12265 O O      . VAL B 1 322 ? -4.624  32.002  -21.612 1.00 18.28  ? 322 VAL B O      1 
ATOM   12266 C CB     . VAL B 1 322 ? -5.979  29.222  -20.270 1.00 17.92  ? 322 VAL B CB     1 
ATOM   12267 C CG1    . VAL B 1 322 ? -7.147  29.914  -20.978 1.00 18.35  ? 322 VAL B CG1    1 
ATOM   12268 C CG2    . VAL B 1 322 ? -6.102  27.700  -20.427 1.00 15.66  ? 322 VAL B CG2    1 
ATOM   12269 H H      . VAL B 1 322 ? -3.752  28.560  -19.483 1.00 19.03  ? 322 VAL B H      1 
ATOM   12270 H HA     . VAL B 1 322 ? -4.572  29.502  -21.765 1.00 17.41  ? 322 VAL B HA     1 
ATOM   12271 H HB     . VAL B 1 322 ? -6.034  29.432  -19.325 1.00 21.50  ? 322 VAL B HB     1 
ATOM   12272 H HG11   . VAL B 1 322 ? -7.974  29.476  -20.722 1.00 22.02  ? 322 VAL B HG11   1 
ATOM   12273 H HG12   . VAL B 1 322 ? -7.172  30.847  -20.713 1.00 22.02  ? 322 VAL B HG12   1 
ATOM   12274 H HG13   . VAL B 1 322 ? -7.020  29.844  -21.937 1.00 22.02  ? 322 VAL B HG13   1 
ATOM   12275 H HG21   . VAL B 1 322 ? -6.976  27.420  -20.113 1.00 18.80  ? 322 VAL B HG21   1 
ATOM   12276 H HG22   . VAL B 1 322 ? -5.998  27.471  -21.364 1.00 18.80  ? 322 VAL B HG22   1 
ATOM   12277 H HG23   . VAL B 1 322 ? -5.409  27.270  -19.903 1.00 18.80  ? 322 VAL B HG23   1 
ATOM   12278 N N      . ARG B 1 323 ? -4.166  31.647  -19.443 1.00 16.67  ? 323 ARG B N      1 
ATOM   12279 C CA     . ARG B 1 323 ? -3.993  33.066  -19.124 1.00 14.82  ? 323 ARG B CA     1 
ATOM   12280 C C      . ARG B 1 323 ? -2.881  33.704  -19.951 1.00 17.56  ? 323 ARG B C      1 
ATOM   12281 O O      . ARG B 1 323 ? -2.999  34.846  -20.425 1.00 19.45  ? 323 ARG B O      1 
ATOM   12282 C CB     . ARG B 1 323 ? -3.690  33.231  -17.628 1.00 14.94  ? 323 ARG B CB     1 
ATOM   12283 C CG     . ARG B 1 323 ? -3.546  34.676  -17.174 1.00 22.61  ? 323 ARG B CG     1 
ATOM   12284 C CD     . ARG B 1 323 ? -3.378  34.771  -15.659 1.00 22.62  ? 323 ARG B CD     1 
ATOM   12285 N NE     . ARG B 1 323 ? -4.548  34.263  -14.954 1.00 21.15  ? 323 ARG B NE     1 
ATOM   12286 C CZ     . ARG B 1 323 ? -4.568  33.946  -13.661 1.00 22.52  ? 323 ARG B CZ     1 
ATOM   12287 N NH1    . ARG B 1 323 ? -3.471  34.070  -12.928 1.00 19.00  ? 323 ARG B NH1    1 
ATOM   12288 N NH2    . ARG B 1 323 ? -5.687  33.491  -13.107 1.00 23.34  ? 323 ARG B NH2    1 
ATOM   12289 H H      . ARG B 1 323 ? -4.045  31.124  -18.771 1.00 20.00  ? 323 ARG B H      1 
ATOM   12290 H HA     . ARG B 1 323 ? -4.819  33.537  -19.317 1.00 17.78  ? 323 ARG B HA     1 
ATOM   12291 H HB2    . ARG B 1 323 ? -4.413  32.831  -17.119 1.00 17.93  ? 323 ARG B HB2    1 
ATOM   12292 H HB3    . ARG B 1 323 ? -2.858  32.776  -17.428 1.00 17.93  ? 323 ARG B HB3    1 
ATOM   12293 H HG2    . ARG B 1 323 ? -2.762  35.068  -17.590 1.00 27.14  ? 323 ARG B HG2    1 
ATOM   12294 H HG3    . ARG B 1 323 ? -4.342  35.171  -17.424 1.00 27.14  ? 323 ARG B HG3    1 
ATOM   12295 H HD2    . ARG B 1 323 ? -2.609  34.244  -15.392 1.00 27.14  ? 323 ARG B HD2    1 
ATOM   12296 H HD3    . ARG B 1 323 ? -3.252  35.700  -15.409 1.00 27.14  ? 323 ARG B HD3    1 
ATOM   12297 H HE     . ARG B 1 323 ? -5.274  34.161  -15.403 1.00 25.38  ? 323 ARG B HE     1 
ATOM   12298 H HH11   . ARG B 1 323 ? -2.744  34.363  -13.281 1.00 22.80  ? 323 ARG B HH11   1 
ATOM   12299 H HH12   . ARG B 1 323 ? -3.488  33.862  -12.094 1.00 22.80  ? 323 ARG B HH12   1 
ATOM   12300 H HH21   . ARG B 1 323 ? -6.399  33.407  -13.582 1.00 28.01  ? 323 ARG B HH21   1 
ATOM   12301 H HH22   . ARG B 1 323 ? -5.700  33.282  -12.273 1.00 28.01  ? 323 ARG B HH22   1 
ATOM   12302 N N      . TYR B 1 324 ? -1.802  32.956  -20.130 1.00 17.97  ? 324 TYR B N      1 
ATOM   12303 C CA     . TYR B 1 324 ? -0.670  33.408  -20.915 1.00 17.13  ? 324 TYR B CA     1 
ATOM   12304 C C      . TYR B 1 324 ? -1.118  33.792  -22.329 1.00 19.66  ? 324 TYR B C      1 
ATOM   12305 O O      . TYR B 1 324 ? -0.773  34.862  -22.840 1.00 19.81  ? 324 TYR B O      1 
ATOM   12306 C CB     . TYR B 1 324 ? 0.403   32.315  -20.971 1.00 19.34  ? 324 TYR B CB     1 
ATOM   12307 C CG     . TYR B 1 324 ? 1.576   32.669  -21.837 1.00 20.81  ? 324 TYR B CG     1 
ATOM   12308 C CD1    . TYR B 1 324 ? 2.596   33.472  -21.354 1.00 23.11  ? 324 TYR B CD1    1 
ATOM   12309 C CD2    . TYR B 1 324 ? 1.669   32.204  -23.143 1.00 22.36  ? 324 TYR B CD2    1 
ATOM   12310 C CE1    . TYR B 1 324 ? 3.680   33.805  -22.146 1.00 31.12  ? 324 TYR B CE1    1 
ATOM   12311 C CE2    . TYR B 1 324 ? 2.757   32.529  -23.943 1.00 22.73  ? 324 TYR B CE2    1 
ATOM   12312 C CZ     . TYR B 1 324 ? 3.754   33.331  -23.439 1.00 30.71  ? 324 TYR B CZ     1 
ATOM   12313 O OH     . TYR B 1 324 ? 4.834   33.671  -24.220 1.00 31.13  ? 324 TYR B OH     1 
ATOM   12314 H H      . TYR B 1 324 ? -1.702  32.168  -19.800 1.00 21.57  ? 324 TYR B H      1 
ATOM   12315 H HA     . TYR B 1 324 ? -0.283  34.192  -20.496 1.00 20.56  ? 324 TYR B HA     1 
ATOM   12316 H HB2    . TYR B 1 324 ? 0.734   32.154  -20.073 1.00 23.21  ? 324 TYR B HB2    1 
ATOM   12317 H HB3    . TYR B 1 324 ? 0.009   31.505  -21.327 1.00 23.21  ? 324 TYR B HB3    1 
ATOM   12318 H HD1    . TYR B 1 324 ? 2.550   33.794  -20.483 1.00 27.73  ? 324 TYR B HD1    1 
ATOM   12319 H HD2    . TYR B 1 324 ? 0.995   31.662  -23.485 1.00 26.83  ? 324 TYR B HD2    1 
ATOM   12320 H HE1    . TYR B 1 324 ? 4.357   34.346  -21.808 1.00 37.35  ? 324 TYR B HE1    1 
ATOM   12321 H HE2    . TYR B 1 324 ? 2.807   32.213  -24.816 1.00 27.27  ? 324 TYR B HE2    1 
ATOM   12322 H HH     . TYR B 1 324 ? 4.878   33.160  -24.882 1.00 37.35  ? 324 TYR B HH     1 
ATOM   12323 N N      . LEU B 1 325 ? -1.892  32.909  -22.954 1.00 17.04  ? 325 LEU B N      1 
ATOM   12324 C CA     . LEU B 1 325 ? -2.382  33.151  -24.305 1.00 18.79  ? 325 LEU B CA     1 
ATOM   12325 C C      . LEU B 1 325 ? -3.257  34.404  -24.337 1.00 20.72  ? 325 LEU B C      1 
ATOM   12326 O O      . LEU B 1 325 ? -3.060  35.295  -25.163 1.00 19.00  ? 325 LEU B O      1 
ATOM   12327 C CB     . LEU B 1 325 ? -3.155  31.930  -24.810 1.00 18.78  ? 325 LEU B CB     1 
ATOM   12328 C CG     . LEU B 1 325 ? -3.888  32.107  -26.136 1.00 15.19  ? 325 LEU B CG     1 
ATOM   12329 C CD1    . LEU B 1 325 ? -2.915  32.494  -27.254 1.00 17.84  ? 325 LEU B CD1    1 
ATOM   12330 C CD2    . LEU B 1 325 ? -4.649  30.837  -26.497 1.00 17.99  ? 325 LEU B CD2    1 
ATOM   12331 H H      . LEU B 1 325 ? -2.148  32.161  -22.616 1.00 20.45  ? 325 LEU B H      1 
ATOM   12332 H HA     . LEU B 1 325 ? -1.626  33.296  -24.895 1.00 22.55  ? 325 LEU B HA     1 
ATOM   12333 H HB2    . LEU B 1 325 ? -2.529  31.197  -24.921 1.00 22.53  ? 325 LEU B HB2    1 
ATOM   12334 H HB3    . LEU B 1 325 ? -3.817  31.691  -24.143 1.00 22.53  ? 325 LEU B HB3    1 
ATOM   12335 H HG     . LEU B 1 325 ? -4.538  32.821  -26.047 1.00 18.23  ? 325 LEU B HG     1 
ATOM   12336 H HD11   . LEU B 1 325 ? -3.397  32.519  -28.096 1.00 21.41  ? 325 LEU B HD11   1 
ATOM   12337 H HD12   . LEU B 1 325 ? -2.542  33.368  -27.061 1.00 21.41  ? 325 LEU B HD12   1 
ATOM   12338 H HD13   . LEU B 1 325 ? -2.207  31.833  -27.298 1.00 21.41  ? 325 LEU B HD13   1 
ATOM   12339 H HD21   . LEU B 1 325 ? -5.106  30.973  -27.342 1.00 21.59  ? 325 LEU B HD21   1 
ATOM   12340 H HD22   . LEU B 1 325 ? -4.019  30.104  -26.575 1.00 21.59  ? 325 LEU B HD22   1 
ATOM   12341 H HD23   . LEU B 1 325 ? -5.294  30.646  -25.798 1.00 21.59  ? 325 LEU B HD23   1 
ATOM   12342 N N      . GLY B 1 326 ? -4.209  34.481  -23.414 1.00 17.49  ? 326 GLY B N      1 
ATOM   12343 C CA     . GLY B 1 326 ? -5.108  35.617  -23.362 1.00 20.56  ? 326 GLY B CA     1 
ATOM   12344 C C      . GLY B 1 326 ? -4.376  36.928  -23.123 1.00 22.24  ? 326 GLY B C      1 
ATOM   12345 O O      . GLY B 1 326 ? -4.677  37.933  -23.762 1.00 20.82  ? 326 GLY B O      1 
ATOM   12346 H H      . GLY B 1 326 ? -4.352  33.887  -22.809 1.00 20.99  ? 326 GLY B H      1 
ATOM   12347 H HA2    . GLY B 1 326 ? -5.591  35.684  -24.200 1.00 24.67  ? 326 GLY B HA2    1 
ATOM   12348 H HA3    . GLY B 1 326 ? -5.750  35.487  -22.648 1.00 24.67  ? 326 GLY B HA3    1 
ATOM   12349 N N      . GLU B 1 327 ? -3.409  36.933  -22.209 1.00 21.02  ? 327 GLU B N      1 
ATOM   12350 C CA     . GLU B 1 327 ? -2.711  38.175  -21.872 1.00 23.44  ? 327 GLU B CA     1 
ATOM   12351 C C      . GLU B 1 327 ? -1.817  38.625  -23.015 1.00 24.37  ? 327 GLU B C      1 
ATOM   12352 O O      . GLU B 1 327 ? -1.651  39.823  -23.246 1.00 23.70  ? 327 GLU B O      1 
ATOM   12353 C CB     . GLU B 1 327 ? -1.889  38.015  -20.597 1.00 25.92  ? 327 GLU B CB     1 
ATOM   12354 C CG     . GLU B 1 327 ? -2.744  37.897  -19.351 1.00 33.22  ? 327 GLU B CG     1 
ATOM   12355 C CD     . GLU B 1 327 ? -3.556  39.155  -19.083 1.00 48.04  ? 327 GLU B CD     1 
ATOM   12356 O OE1    . GLU B 1 327 ? -3.033  40.262  -19.336 1.00 44.09  ? 327 GLU B OE1    1 
ATOM   12357 O OE2    . GLU B 1 327 ? -4.717  39.035  -18.633 1.00 46.35  ? 327 GLU B OE2    1 
ATOM   12358 H H      . GLU B 1 327 ? -3.140  36.242  -21.774 1.00 25.23  ? 327 GLU B H      1 
ATOM   12359 H HA     . GLU B 1 327 ? -3.368  38.872  -21.722 1.00 28.12  ? 327 GLU B HA     1 
ATOM   12360 H HB2    . GLU B 1 327 ? -1.354  37.209  -20.668 1.00 31.10  ? 327 GLU B HB2    1 
ATOM   12361 H HB3    . GLU B 1 327 ? -1.311  38.787  -20.494 1.00 31.10  ? 327 GLU B HB3    1 
ATOM   12362 H HG2    . GLU B 1 327 ? -3.364  37.159  -19.459 1.00 39.87  ? 327 GLU B HG2    1 
ATOM   12363 H HG3    . GLU B 1 327 ? -2.169  37.740  -18.585 1.00 39.87  ? 327 GLU B HG3    1 
ATOM   12364 N N      . LYS B 1 328 ? -1.240  37.672  -23.736 1.00 20.03  ? 328 LYS B N      1 
ATOM   12365 C CA     . LYS B 1 328 ? -0.420  38.014  -24.888 1.00 25.83  ? 328 LYS B CA     1 
ATOM   12366 C C      . LYS B 1 328 ? -1.274  38.650  -25.988 1.00 23.01  ? 328 LYS B C      1 
ATOM   12367 O O      . LYS B 1 328 ? -0.841  39.593  -26.655 1.00 27.02  ? 328 LYS B O      1 
ATOM   12368 C CB     . LYS B 1 328 ? 0.303   36.788  -25.424 1.00 23.17  ? 328 LYS B CB     1 
ATOM   12369 C CG     . LYS B 1 328 ? 1.177   37.111  -26.591 1.00 27.98  ? 328 LYS B CG     1 
ATOM   12370 C CD     . LYS B 1 328 ? 2.211   36.043  -26.848 1.00 33.81  ? 328 LYS B CD     1 
ATOM   12371 C CE     . LYS B 1 328 ? 3.145   36.501  -27.950 1.00 34.45  ? 328 LYS B CE     1 
ATOM   12372 N NZ     . LYS B 1 328 ? 4.139   35.465  -28.307 1.00 42.72  ? 328 LYS B NZ     1 
ATOM   12373 H H      . LYS B 1 328 ? -1.306  36.829  -23.581 1.00 24.03  ? 328 LYS B H      1 
ATOM   12374 H HA     . LYS B 1 328 ? 0.250   38.661  -24.617 1.00 30.99  ? 328 LYS B HA     1 
ATOM   12375 H HB2    . LYS B 1 328 ? 0.861   36.417  -24.723 1.00 27.80  ? 328 LYS B HB2    1 
ATOM   12376 H HB3    . LYS B 1 328 ? -0.352  36.133  -25.710 1.00 27.80  ? 328 LYS B HB3    1 
ATOM   12377 H HG2    . LYS B 1 328 ? 0.628   37.194  -27.386 1.00 33.57  ? 328 LYS B HG2    1 
ATOM   12378 H HG3    . LYS B 1 328 ? 1.642   37.945  -26.418 1.00 33.57  ? 328 LYS B HG3    1 
ATOM   12379 H HD2    . LYS B 1 328 ? 2.731   35.891  -26.043 1.00 40.58  ? 328 LYS B HD2    1 
ATOM   12380 H HD3    . LYS B 1 328 ? 1.773   35.225  -27.132 1.00 40.58  ? 328 LYS B HD3    1 
ATOM   12381 H HE2    . LYS B 1 328 ? 2.625   36.706  -28.743 1.00 41.34  ? 328 LYS B HE2    1 
ATOM   12382 H HE3    . LYS B 1 328 ? 3.625   37.290  -27.653 1.00 41.34  ? 328 LYS B HE3    1 
ATOM   12383 H HZ1    . LYS B 1 328 ? 4.671   35.764  -28.955 1.00 51.27  ? 328 LYS B HZ1    1 
ATOM   12384 H HZ2    . LYS B 1 328 ? 4.635   35.262  -27.596 1.00 51.27  ? 328 LYS B HZ2    1 
ATOM   12385 H HZ3    . LYS B 1 328 ? 3.724   34.730  -28.590 1.00 51.27  ? 328 LYS B HZ3    1 
ATOM   12386 N N      . LEU B 1 329 ? -2.493  38.151  -26.161 1.00 18.97  ? 329 LEU B N      1 
ATOM   12387 C CA     . LEU B 1 329 ? -3.402  38.726  -27.148 1.00 21.65  ? 329 LEU B CA     1 
ATOM   12388 C C      . LEU B 1 329 ? -3.865  40.106  -26.680 1.00 23.30  ? 329 LEU B C      1 
ATOM   12389 O O      . LEU B 1 329 ? -3.876  41.070  -27.456 1.00 20.46  ? 329 LEU B O      1 
ATOM   12390 C CB     . LEU B 1 329 ? -4.603  37.801  -27.384 1.00 19.17  ? 329 LEU B CB     1 
ATOM   12391 C CG     . LEU B 1 329 ? -4.256  36.477  -28.071 1.00 17.53  ? 329 LEU B CG     1 
ATOM   12392 C CD1    . LEU B 1 329 ? -5.435  35.536  -28.093 1.00 20.26  ? 329 LEU B CD1    1 
ATOM   12393 C CD2    . LEU B 1 329 ? -3.772  36.724  -29.493 1.00 19.45  ? 329 LEU B CD2    1 
ATOM   12394 H H      . LEU B 1 329 ? -2.817  37.485  -25.724 1.00 22.76  ? 329 LEU B H      1 
ATOM   12395 H HA     . LEU B 1 329 ? -2.932  38.837  -27.989 1.00 25.98  ? 329 LEU B HA     1 
ATOM   12396 H HB2    . LEU B 1 329 ? -5.006  37.591  -26.527 1.00 23.00  ? 329 LEU B HB2    1 
ATOM   12397 H HB3    . LEU B 1 329 ? -5.246  38.263  -27.943 1.00 23.00  ? 329 LEU B HB3    1 
ATOM   12398 H HG     . LEU B 1 329 ? -3.538  36.046  -27.582 1.00 21.03  ? 329 LEU B HG     1 
ATOM   12399 H HD11   . LEU B 1 329 ? -5.174  34.713  -28.535 1.00 24.31  ? 329 LEU B HD11   1 
ATOM   12400 H HD12   . LEU B 1 329 ? -5.707  35.350  -27.181 1.00 24.31  ? 329 LEU B HD12   1 
ATOM   12401 H HD13   . LEU B 1 329 ? -6.164  35.955  -28.577 1.00 24.31  ? 329 LEU B HD13   1 
ATOM   12402 H HD21   . LEU B 1 329 ? -3.714  35.875  -29.958 1.00 23.34  ? 329 LEU B HD21   1 
ATOM   12403 H HD22   . LEU B 1 329 ? -4.403  37.306  -29.944 1.00 23.34  ? 329 LEU B HD22   1 
ATOM   12404 H HD23   . LEU B 1 329 ? -2.898  37.144  -29.462 1.00 23.34  ? 329 LEU B HD23   1 
ATOM   12405 N N      . LYS B 1 330 ? -4.228  40.199  -25.404 1.00 24.07  ? 330 LYS B N      1 
ATOM   12406 C CA     . LYS B 1 330 ? -4.729  41.453  -24.841 1.00 27.79  ? 330 LYS B CA     1 
ATOM   12407 C C      . LYS B 1 330 ? -3.671  42.543  -24.971 1.00 26.91  ? 330 LYS B C      1 
ATOM   12408 O O      . LYS B 1 330 ? -3.991  43.691  -25.272 1.00 28.16  ? 330 LYS B O      1 
ATOM   12409 C CB     . LYS B 1 330 ? -5.139  41.261  -23.372 1.00 27.92  ? 330 LYS B CB     1 
ATOM   12410 C CG     . LYS B 1 330 ? -5.896  42.429  -22.765 1.00 44.52  ? 330 LYS B CG     1 
ATOM   12411 C CD     . LYS B 1 330 ? -6.565  42.045  -21.441 1.00 44.26  ? 330 LYS B CD     1 
ATOM   12412 C CE     . LYS B 1 330 ? -5.545  41.653  -20.384 1.00 57.87  ? 330 LYS B CE     1 
ATOM   12413 N NZ     . LYS B 1 330 ? -6.164  41.421  -19.042 1.00 51.87  ? 330 LYS B NZ     1 
ATOM   12414 H H      . LYS B 1 330 ? -4.194  39.550  -24.841 1.00 28.88  ? 330 LYS B H      1 
ATOM   12415 H HA     . LYS B 1 330 ? -5.513  41.733  -25.338 1.00 33.34  ? 330 LYS B HA     1 
ATOM   12416 H HB2    . LYS B 1 330 ? -5.708  40.478  -23.309 1.00 33.51  ? 330 LYS B HB2    1 
ATOM   12417 H HB3    . LYS B 1 330 ? -4.337  41.124  -22.844 1.00 33.51  ? 330 LYS B HB3    1 
ATOM   12418 H HG2    . LYS B 1 330 ? -5.277  43.156  -22.592 1.00 53.42  ? 330 LYS B HG2    1 
ATOM   12419 H HG3    . LYS B 1 330 ? -6.587  42.717  -23.382 1.00 53.42  ? 330 LYS B HG3    1 
ATOM   12420 H HD2    . LYS B 1 330 ? -7.071  42.803  -21.108 1.00 53.12  ? 330 LYS B HD2    1 
ATOM   12421 H HD3    . LYS B 1 330 ? -7.154  41.289  -21.589 1.00 53.12  ? 330 LYS B HD3    1 
ATOM   12422 H HE2    . LYS B 1 330 ? -5.110  40.831  -20.658 1.00 69.45  ? 330 LYS B HE2    1 
ATOM   12423 H HE3    . LYS B 1 330 ? -4.890  42.363  -20.295 1.00 69.45  ? 330 LYS B HE3    1 
ATOM   12424 H HZ1    . LYS B 1 330 ? -5.537  41.194  -18.453 1.00 62.24  ? 330 LYS B HZ1    1 
ATOM   12425 H HZ2    . LYS B 1 330 ? -6.569  42.162  -18.762 1.00 62.24  ? 330 LYS B HZ2    1 
ATOM   12426 H HZ3    . LYS B 1 330 ? -6.763  40.765  -19.093 1.00 62.24  ? 330 LYS B HZ3    1 
ATOM   12427 N N      . ALA B 1 331 ? -2.409  42.171  -24.772 1.00 23.54  ? 331 ALA B N      1 
ATOM   12428 C CA     . ALA B 1 331 ? -1.299  43.121  -24.834 1.00 27.46  ? 331 ALA B CA     1 
ATOM   12429 C C      . ALA B 1 331 ? -1.149  43.727  -26.224 1.00 32.60  ? 331 ALA B C      1 
ATOM   12430 O O      . ALA B 1 331 ? -0.670  44.849  -26.369 1.00 25.33  ? 331 ALA B O      1 
ATOM   12431 C CB     . ALA B 1 331 ? 0.000   42.447  -24.423 1.00 28.85  ? 331 ALA B CB     1 
ATOM   12432 H H      . ALA B 1 331 ? -2.166  41.365  -24.597 1.00 28.24  ? 331 ALA B H      1 
ATOM   12433 H HA     . ALA B 1 331 ? -1.470  43.844  -24.211 1.00 32.96  ? 331 ALA B HA     1 
ATOM   12434 H HB1    . ALA B 1 331 ? 0.720   43.095  -24.472 1.00 34.62  ? 331 ALA B HB1    1 
ATOM   12435 H HB2    . ALA B 1 331 ? -0.089  42.118  -23.515 1.00 34.62  ? 331 ALA B HB2    1 
ATOM   12436 H HB3    . ALA B 1 331 ? 0.177   41.709  -25.027 1.00 34.62  ? 331 ALA B HB3    1 
ATOM   12437 N N      . ALA B 1 332 ? -1.555  42.979  -27.243 1.00 23.89  ? 332 ALA B N      1 
ATOM   12438 C CA     . ALA B 1 332 ? -1.429  43.425  -28.624 1.00 27.32  ? 332 ALA B CA     1 
ATOM   12439 C C      . ALA B 1 332 ? -2.690  44.153  -29.094 1.00 24.25  ? 332 ALA B C      1 
ATOM   12440 O O      . ALA B 1 332 ? -2.778  44.576  -30.249 1.00 27.43  ? 332 ALA B O      1 
ATOM   12441 C CB     . ALA B 1 332 ? -1.129  42.235  -29.529 1.00 28.02  ? 332 ALA B CB     1 
ATOM   12442 H H      . ALA B 1 332 ? -1.910  42.200  -27.160 1.00 28.67  ? 332 ALA B H      1 
ATOM   12443 H HA     . ALA B 1 332 ? -0.685  44.042  -28.695 1.00 32.79  ? 332 ALA B HA     1 
ATOM   12444 H HB1    . ALA B 1 332 ? -1.047  42.547  -30.444 1.00 33.62  ? 332 ALA B HB1    1 
ATOM   12445 H HB2    . ALA B 1 332 ? -0.298  41.823  -29.244 1.00 33.62  ? 332 ALA B HB2    1 
ATOM   12446 H HB3    . ALA B 1 332 ? -1.856  41.596  -29.461 1.00 33.62  ? 332 ALA B HB3    1 
ATOM   12447 N N      . GLY B 1 333 ? -3.667  44.291  -28.203 1.00 25.01  ? 333 GLY B N      1 
ATOM   12448 C CA     . GLY B 1 333 ? -4.907  44.973  -28.523 1.00 28.94  ? 333 GLY B CA     1 
ATOM   12449 C C      . GLY B 1 333 ? -5.971  44.107  -29.183 1.00 28.79  ? 333 GLY B C      1 
ATOM   12450 O O      . GLY B 1 333 ? -6.983  44.622  -29.664 1.00 23.68  ? 333 GLY B O      1 
ATOM   12451 H H      . GLY B 1 333 ? -3.635  43.995  -27.397 1.00 30.01  ? 333 GLY B H      1 
ATOM   12452 H HA2    . GLY B 1 333 ? -5.284  45.333  -27.705 1.00 34.73  ? 333 GLY B HA2    1 
ATOM   12453 H HA3    . GLY B 1 333 ? -4.717  45.717  -29.116 1.00 34.73  ? 333 GLY B HA3    1 
ATOM   12454 N N      . VAL B 1 334 ? -5.765  42.793  -29.207 1.00 25.43  ? 334 VAL B N      1 
ATOM   12455 C CA     . VAL B 1 334 ? -6.755  41.900  -29.796 1.00 21.72  ? 334 VAL B CA     1 
ATOM   12456 C C      . VAL B 1 334 ? -7.999  41.828  -28.914 1.00 23.88  ? 334 VAL B C      1 
ATOM   12457 O O      . VAL B 1 334 ? -7.884  41.600  -27.718 1.00 24.45  ? 334 VAL B O      1 
ATOM   12458 C CB     . VAL B 1 334 ? -6.179  40.487  -29.990 1.00 23.77  ? 334 VAL B CB     1 
ATOM   12459 C CG1    . VAL B 1 334 ? -7.243  39.545  -30.531 1.00 20.25  ? 334 VAL B CG1    1 
ATOM   12460 C CG2    . VAL B 1 334 ? -4.973  40.535  -30.917 1.00 22.95  ? 334 VAL B CG2    1 
ATOM   12461 H H      . VAL B 1 334 ? -5.069  42.398  -28.893 1.00 30.51  ? 334 VAL B H      1 
ATOM   12462 H HA     . VAL B 1 334 ? -6.999  42.242  -30.668 1.00 26.07  ? 334 VAL B HA     1 
ATOM   12463 H HB     . VAL B 1 334 ? -5.884  40.146  -29.131 1.00 28.53  ? 334 VAL B HB     1 
ATOM   12464 H HG11   . VAL B 1 334 ? -6.811  38.739  -30.855 1.00 24.30  ? 334 VAL B HG11   1 
ATOM   12465 H HG12   . VAL B 1 334 ? -7.864  39.321  -29.821 1.00 24.30  ? 334 VAL B HG12   1 
ATOM   12466 H HG13   . VAL B 1 334 ? -7.711  39.982  -31.259 1.00 24.30  ? 334 VAL B HG13   1 
ATOM   12467 H HG21   . VAL B 1 334 ? -4.651  39.632  -31.063 1.00 27.54  ? 334 VAL B HG21   1 
ATOM   12468 H HG22   . VAL B 1 334 ? -5.240  40.931  -31.761 1.00 27.54  ? 334 VAL B HG22   1 
ATOM   12469 H HG23   . VAL B 1 334 ? -4.278  41.071  -30.504 1.00 27.54  ? 334 VAL B HG23   1 
ATOM   12470 N N      . PRO B 1 335 ? -9.196  42.019  -29.496 1.00 24.58  ? 335 PRO B N      1 
ATOM   12471 C CA     . PRO B 1 335 ? -10.397 41.981  -28.654 1.00 26.86  ? 335 PRO B CA     1 
ATOM   12472 C C      . PRO B 1 335 ? -10.771 40.570  -28.216 1.00 27.75  ? 335 PRO B C      1 
ATOM   12473 O O      . PRO B 1 335 ? -11.007 39.704  -29.060 1.00 23.88  ? 335 PRO B O      1 
ATOM   12474 C CB     . PRO B 1 335 ? -11.480 42.567  -29.564 1.00 28.71  ? 335 PRO B CB     1 
ATOM   12475 C CG     . PRO B 1 335 ? -11.013 42.245  -30.937 1.00 26.23  ? 335 PRO B CG     1 
ATOM   12476 C CD     . PRO B 1 335 ? -9.519  42.371  -30.888 1.00 23.64  ? 335 PRO B CD     1 
ATOM   12477 H HA     . PRO B 1 335 ? -10.287 42.547  -27.874 1.00 32.23  ? 335 PRO B HA     1 
ATOM   12478 H HB2    . PRO B 1 335 ? -12.332 42.141  -29.379 1.00 34.45  ? 335 PRO B HB2    1 
ATOM   12479 H HB3    . PRO B 1 335 ? -11.536 43.527  -29.434 1.00 34.45  ? 335 PRO B HB3    1 
ATOM   12480 H HG2    . PRO B 1 335 ? -11.273 41.339  -31.166 1.00 31.47  ? 335 PRO B HG2    1 
ATOM   12481 H HG3    . PRO B 1 335 ? -11.390 42.879  -31.567 1.00 31.47  ? 335 PRO B HG3    1 
ATOM   12482 H HD2    . PRO B 1 335 ? -9.107  41.744  -31.502 1.00 28.37  ? 335 PRO B HD2    1 
ATOM   12483 H HD3    . PRO B 1 335 ? -9.250  43.284  -31.077 1.00 28.37  ? 335 PRO B HD3    1 
ATOM   12484 N N      . ILE B 1 336 ? -10.819 40.352  -26.906 1.00 26.39  ? 336 ILE B N      1 
ATOM   12485 C CA     . ILE B 1 336 ? -11.171 39.056  -26.349 1.00 24.49  ? 336 ILE B CA     1 
ATOM   12486 C C      . ILE B 1 336 ? -12.213 39.226  -25.249 1.00 26.10  ? 336 ILE B C      1 
ATOM   12487 O O      . ILE B 1 336 ? -12.359 40.314  -24.695 1.00 25.70  ? 336 ILE B O      1 
ATOM   12488 C CB     . ILE B 1 336 ? -9.925  38.327  -25.778 1.00 25.03  ? 336 ILE B CB     1 
ATOM   12489 C CG1    . ILE B 1 336 ? -9.340  39.061  -24.564 1.00 26.77  ? 336 ILE B CG1    1 
ATOM   12490 C CG2    . ILE B 1 336 ? -8.851  38.194  -26.847 1.00 23.99  ? 336 ILE B CG2    1 
ATOM   12491 C CD1    . ILE B 1 336 ? -8.395  38.187  -23.729 1.00 24.76  ? 336 ILE B CD1    1 
ATOM   12492 H H      . ILE B 1 336 ? -10.649 40.950  -26.312 1.00 31.66  ? 336 ILE B H      1 
ATOM   12493 H HA     . ILE B 1 336 ? -11.557 38.499  -27.041 1.00 29.39  ? 336 ILE B HA     1 
ATOM   12494 H HB     . ILE B 1 336 ? -10.192 37.437  -25.499 1.00 30.04  ? 336 ILE B HB     1 
ATOM   12495 H HG12   . ILE B 1 336 ? -8.835  39.828  -24.877 1.00 32.13  ? 336 ILE B HG12   1 
ATOM   12496 H HG13   . ILE B 1 336 ? -10.050 39.355  -23.975 1.00 32.13  ? 336 ILE B HG13   1 
ATOM   12497 H HG21   . ILE B 1 336 ? -8.126  37.650  -26.501 1.00 28.79  ? 336 ILE B HG21   1 
ATOM   12498 H HG22   . ILE B 1 336 ? -9.237  37.771  -27.630 1.00 28.79  ? 336 ILE B HG22   1 
ATOM   12499 H HG23   . ILE B 1 336 ? -8.522  39.077  -27.077 1.00 28.79  ? 336 ILE B HG23   1 
ATOM   12500 H HD11   . ILE B 1 336 ? -8.098  38.693  -22.956 1.00 29.71  ? 336 ILE B HD11   1 
ATOM   12501 H HD12   . ILE B 1 336 ? -8.872  37.393  -23.442 1.00 29.71  ? 336 ILE B HD12   1 
ATOM   12502 H HD13   . ILE B 1 336 ? -7.632  37.937  -24.273 1.00 29.71  ? 336 ILE B HD13   1 
ATOM   12503 N N      . VAL B 1 337 ? -12.932 38.151  -24.944 1.00 23.56  ? 337 VAL B N      1 
ATOM   12504 C CA     . VAL B 1 337 ? -13.804 38.108  -23.780 1.00 26.36  ? 337 VAL B CA     1 
ATOM   12505 C C      . VAL B 1 337 ? -12.919 38.240  -22.548 1.00 28.12  ? 337 VAL B C      1 
ATOM   12506 O O      . VAL B 1 337 ? -11.833 37.663  -22.502 1.00 24.65  ? 337 VAL B O      1 
ATOM   12507 C CB     . VAL B 1 337 ? -14.618 36.802  -23.735 1.00 27.89  ? 337 VAL B CB     1 
ATOM   12508 C CG1    . VAL B 1 337 ? -15.380 36.663  -22.405 1.00 31.54  ? 337 VAL B CG1    1 
ATOM   12509 C CG2    . VAL B 1 337 ? -15.569 36.739  -24.928 1.00 26.71  ? 337 VAL B CG2    1 
ATOM   12510 H H      . VAL B 1 337 ? -12.931 37.424  -25.404 1.00 28.27  ? 337 VAL B H      1 
ATOM   12511 H HA     . VAL B 1 337 ? -14.419 38.858  -23.804 1.00 31.63  ? 337 VAL B HA     1 
ATOM   12512 H HB     . VAL B 1 337 ? -14.007 36.052  -23.804 1.00 33.46  ? 337 VAL B HB     1 
ATOM   12513 H HG11   . VAL B 1 337 ? -16.040 35.958  -22.494 1.00 37.85  ? 337 VAL B HG11   1 
ATOM   12514 H HG12   . VAL B 1 337 ? -14.753 36.439  -21.700 1.00 37.85  ? 337 VAL B HG12   1 
ATOM   12515 H HG13   . VAL B 1 337 ? -15.820 37.504  -22.205 1.00 37.85  ? 337 VAL B HG13   1 
ATOM   12516 H HG21   . VAL B 1 337 ? -16.085 35.919  -24.877 1.00 32.05  ? 337 VAL B HG21   1 
ATOM   12517 H HG22   . VAL B 1 337 ? -16.162 37.506  -24.899 1.00 32.05  ? 337 VAL B HG22   1 
ATOM   12518 H HG23   . VAL B 1 337 ? -15.049 36.752  -25.747 1.00 32.05  ? 337 VAL B HG23   1 
ATOM   12519 N N      . GLU B 1 338 ? -13.369 39.019  -21.565 1.00 27.76  ? 338 GLU B N      1 
ATOM   12520 C CA     . GLU B 1 338 ? -12.599 39.235  -20.339 1.00 26.07  ? 338 GLU B CA     1 
ATOM   12521 C C      . GLU B 1 338 ? -13.471 38.979  -19.114 1.00 24.41  ? 338 GLU B C      1 
ATOM   12522 O O      . GLU B 1 338 ? -14.687 39.080  -19.197 1.00 33.01  ? 338 GLU B O      1 
ATOM   12523 C CB     . GLU B 1 338 ? -12.040 40.661  -20.284 1.00 31.48  ? 338 GLU B CB     1 
ATOM   12524 C CG     . GLU B 1 338 ? -11.021 40.982  -21.362 1.00 30.22  ? 338 GLU B CG     1 
ATOM   12525 C CD     . GLU B 1 338 ? -10.488 42.401  -21.251 1.00 43.94  ? 338 GLU B CD     1 
ATOM   12526 O OE1    . GLU B 1 338 ? -9.997  42.768  -20.163 1.00 41.21  ? 338 GLU B OE1    1 
ATOM   12527 O OE2    . GLU B 1 338 ? -10.564 43.148  -22.250 1.00 42.85  ? 338 GLU B OE2    1 
ATOM   12528 H H      . GLU B 1 338 ? -14.121 39.436  -21.583 1.00 33.31  ? 338 GLU B H      1 
ATOM   12529 H HA     . GLU B 1 338 ? -11.850 38.625  -20.331 1.00 31.28  ? 338 GLU B HA     1 
ATOM   12530 H HB2    . GLU B 1 338 ? -12.776 41.286  -20.380 1.00 37.77  ? 338 GLU B HB2    1 
ATOM   12531 H HB3    . GLU B 1 338 ? -11.610 40.792  -19.425 1.00 37.77  ? 338 GLU B HB3    1 
ATOM   12532 H HG2    . GLU B 1 338 ? -10.271 40.372  -21.282 1.00 36.26  ? 338 GLU B HG2    1 
ATOM   12533 H HG3    . GLU B 1 338 ? -11.438 40.884  -22.232 1.00 36.26  ? 338 GLU B HG3    1 
ATOM   12534 N N      . PRO B 1 339 ? -12.859 38.597  -17.983 1.00 25.85  ? 339 PRO B N      1 
ATOM   12535 C CA     . PRO B 1 339 ? -11.454 38.196  -17.875 1.00 28.18  ? 339 PRO B CA     1 
ATOM   12536 C C      . PRO B 1 339 ? -11.261 36.835  -18.542 1.00 25.35  ? 339 PRO B C      1 
ATOM   12537 O O      . PRO B 1 339 ? -12.250 36.166  -18.830 1.00 23.68  ? 339 PRO B O      1 
ATOM   12538 C CB     . PRO B 1 339 ? -11.209 38.117  -16.362 1.00 30.94  ? 339 PRO B CB     1 
ATOM   12539 C CG     . PRO B 1 339 ? -12.558 38.210  -15.700 1.00 28.50  ? 339 PRO B CG     1 
ATOM   12540 C CD     . PRO B 1 339 ? -13.615 38.276  -16.760 1.00 30.60  ? 339 PRO B CD     1 
ATOM   12541 H HA     . PRO B 1 339 ? -10.865 38.855  -18.274 1.00 33.82  ? 339 PRO B HA     1 
ATOM   12542 H HB2    . PRO B 1 339 ? -10.785 37.271  -16.148 1.00 37.13  ? 339 PRO B HB2    1 
ATOM   12543 H HB3    . PRO B 1 339 ? -10.646 38.857  -16.088 1.00 37.13  ? 339 PRO B HB3    1 
ATOM   12544 H HG2    . PRO B 1 339 ? -12.692 37.425  -15.146 1.00 34.20  ? 339 PRO B HG2    1 
ATOM   12545 H HG3    . PRO B 1 339 ? -12.587 39.011  -15.153 1.00 34.20  ? 339 PRO B HG3    1 
ATOM   12546 H HD2    . PRO B 1 339 ? -14.057 37.418  -16.853 1.00 36.72  ? 339 PRO B HD2    1 
ATOM   12547 H HD3    . PRO B 1 339 ? -14.249 38.982  -16.560 1.00 36.72  ? 339 PRO B HD3    1 
ATOM   12548 N N      . VAL B 1 340 ? -10.021 36.446  -18.803 1.00 22.55  ? 340 VAL B N      1 
ATOM   12549 C CA     . VAL B 1 340 ? -9.759  35.146  -19.410 1.00 22.11  ? 340 VAL B CA     1 
ATOM   12550 C C      . VAL B 1 340 ? -10.236 34.044  -18.469 1.00 23.04  ? 340 VAL B C      1 
ATOM   12551 O O      . VAL B 1 340 ? -9.952  34.076  -17.270 1.00 22.19  ? 340 VAL B O      1 
ATOM   12552 C CB     . VAL B 1 340 ? -8.271  34.977  -19.727 1.00 23.13  ? 340 VAL B CB     1 
ATOM   12553 C CG1    . VAL B 1 340 ? -7.978  33.577  -20.260 1.00 23.92  ? 340 VAL B CG1    1 
ATOM   12554 C CG2    . VAL B 1 340 ? -7.842  36.025  -20.738 1.00 25.63  ? 340 VAL B CG2    1 
ATOM   12555 H H      . VAL B 1 340 ? -9.317  36.911  -18.639 1.00 27.06  ? 340 VAL B H      1 
ATOM   12556 H HA     . VAL B 1 340 ? -10.256 35.074  -20.240 1.00 26.53  ? 340 VAL B HA     1 
ATOM   12557 H HB     . VAL B 1 340 ? -7.755  35.108  -18.916 1.00 27.75  ? 340 VAL B HB     1 
ATOM   12558 H HG11   . VAL B 1 340 ? -7.098  33.575  -20.669 1.00 28.71  ? 340 VAL B HG11   1 
ATOM   12559 H HG12   . VAL B 1 340 ? -8.001  32.945  -19.525 1.00 28.71  ? 340 VAL B HG12   1 
ATOM   12560 H HG13   . VAL B 1 340 ? -8.649  33.344  -20.921 1.00 28.71  ? 340 VAL B HG13   1 
ATOM   12561 H HG21   . VAL B 1 340 ? -6.876  36.003  -20.819 1.00 30.75  ? 340 VAL B HG21   1 
ATOM   12562 H HG22   . VAL B 1 340 ? -8.252  35.825  -21.594 1.00 30.75  ? 340 VAL B HG22   1 
ATOM   12563 H HG23   . VAL B 1 340 ? -8.125  36.900  -20.431 1.00 30.75  ? 340 VAL B HG23   1 
ATOM   12564 N N      . GLY B 1 341 ? -10.967 33.079  -19.017 1.00 21.01  ? 341 GLY B N      1 
ATOM   12565 C CA     . GLY B 1 341 ? -11.510 31.991  -18.220 1.00 25.09  ? 341 GLY B CA     1 
ATOM   12566 C C      . GLY B 1 341 ? -10.516 30.864  -18.014 1.00 21.03  ? 341 GLY B C      1 
ATOM   12567 O O      . GLY B 1 341 ? -9.344  30.988  -18.344 1.00 20.65  ? 341 GLY B O      1 
ATOM   12568 H H      . GLY B 1 341 ? -11.162 33.033  -19.853 1.00 25.22  ? 341 GLY B H      1 
ATOM   12569 H HA2    . GLY B 1 341 ? -11.777 32.327  -17.350 1.00 30.11  ? 341 GLY B HA2    1 
ATOM   12570 H HA3    . GLY B 1 341 ? -12.291 31.625  -18.657 1.00 30.11  ? 341 GLY B HA3    1 
ATOM   12571 N N      . GLY B 1 342 ? -10.999 29.753  -17.478 1.00 19.05  ? 342 GLY B N      1 
ATOM   12572 C CA     . GLY B 1 342 ? -10.119 28.681  -17.062 1.00 17.08  ? 342 GLY B CA     1 
ATOM   12573 C C      . GLY B 1 342 ? -9.604  27.798  -18.183 1.00 17.91  ? 342 GLY B C      1 
ATOM   12574 O O      . GLY B 1 342 ? -8.549  27.187  -18.027 1.00 19.01  ? 342 GLY B O      1 
ATOM   12575 H H      . GLY B 1 342 ? -11.834 29.597  -17.345 1.00 22.86  ? 342 GLY B H      1 
ATOM   12576 H HA2    . GLY B 1 342 ? -9.352  29.062  -16.606 1.00 20.49  ? 342 GLY B HA2    1 
ATOM   12577 H HA3    . GLY B 1 342 ? -10.591 28.115  -16.431 1.00 20.49  ? 342 GLY B HA3    1 
ATOM   12578 N N      . HIS B 1 343 ? -10.322 27.738  -19.309 1.00 17.90  ? 343 HIS B N      1 
ATOM   12579 C CA     . HIS B 1 343 ? -10.113 26.661  -20.290 1.00 17.44  ? 343 HIS B CA     1 
ATOM   12580 C C      . HIS B 1 343 ? -9.995  27.132  -21.733 1.00 16.95  ? 343 HIS B C      1 
ATOM   12581 O O      . HIS B 1 343 ? -9.707  26.330  -22.626 1.00 18.16  ? 343 HIS B O      1 
ATOM   12582 C CB     . HIS B 1 343 ? -11.264 25.647  -20.202 1.00 17.96  ? 343 HIS B CB     1 
ATOM   12583 C CG     . HIS B 1 343 ? -12.559 26.164  -20.749 1.00 21.46  ? 343 HIS B CG     1 
ATOM   12584 N ND1    . HIS B 1 343 ? -13.270 27.182  -20.149 1.00 21.72  ? 343 HIS B ND1    1 
ATOM   12585 C CD2    . HIS B 1 343 ? -13.257 25.826  -21.861 1.00 20.45  ? 343 HIS B CD2    1 
ATOM   12586 C CE1    . HIS B 1 343 ? -14.354 27.440  -20.860 1.00 24.28  ? 343 HIS B CE1    1 
ATOM   12587 N NE2    . HIS B 1 343 ? -14.369 26.630  -21.903 1.00 22.35  ? 343 HIS B NE2    1 
ATOM   12588 H H      . HIS B 1 343 ? -10.932 28.303  -19.529 1.00 21.48  ? 343 HIS B H      1 
ATOM   12589 H HA     . HIS B 1 343 ? -9.294  26.188  -20.077 1.00 20.92  ? 343 HIS B HA     1 
ATOM   12590 H HB2    . HIS B 1 343 ? -11.023 24.855  -20.707 1.00 21.56  ? 343 HIS B HB2    1 
ATOM   12591 H HB3    . HIS B 1 343 ? -11.406 25.413  -19.272 1.00 21.56  ? 343 HIS B HB3    1 
ATOM   12592 H HD1    . HIS B 1 343 ? -13.044 27.585  -19.424 1.00 26.06  ? 343 HIS B HD1    1 
ATOM   12593 H HD2    . HIS B 1 343 ? -13.028 25.168  -22.478 1.00 24.54  ? 343 HIS B HD2    1 
ATOM   12594 H HE1    . HIS B 1 343 ? -14.998 28.080  -20.658 1.00 29.14  ? 343 HIS B HE1    1 
ATOM   12595 N N      . ALA B 1 344 ? -10.196 28.421  -21.970 1.00 17.55  ? 344 ALA B N      1 
ATOM   12596 C CA     . ALA B 1 344 ? -10.281 28.913  -23.333 1.00 15.81  ? 344 ALA B CA     1 
ATOM   12597 C C      . ALA B 1 344 ? -10.131 30.411  -23.373 1.00 17.94  ? 344 ALA B C      1 
ATOM   12598 O O      . ALA B 1 344 ? -10.371 31.099  -22.382 1.00 16.02  ? 344 ALA B O      1 
ATOM   12599 C CB     . ALA B 1 344 ? -11.599 28.515  -23.953 1.00 20.43  ? 344 ALA B CB     1 
ATOM   12600 H H      . ALA B 1 344 ? -10.285 29.026  -21.365 1.00 21.06  ? 344 ALA B H      1 
ATOM   12601 H HA     . ALA B 1 344 ? -9.565  28.523  -23.857 1.00 18.97  ? 344 ALA B HA     1 
ATOM   12602 H HB1    . ALA B 1 344 ? -11.632 28.845  -24.864 1.00 24.51  ? 344 ALA B HB1    1 
ATOM   12603 H HB2    . ALA B 1 344 ? -11.670 27.548  -23.948 1.00 24.51  ? 344 ALA B HB2    1 
ATOM   12604 H HB3    . ALA B 1 344 ? -12.321 28.902  -23.434 1.00 24.51  ? 344 ALA B HB3    1 
ATOM   12605 N N      . VAL B 1 345 ? -9.711  30.892  -24.534 1.00 16.76  ? 345 VAL B N      1 
ATOM   12606 C CA     . VAL B 1 345 ? -9.742  32.308  -24.860 1.00 18.15  ? 345 VAL B CA     1 
ATOM   12607 C C      . VAL B 1 345 ? -10.759 32.476  -25.977 1.00 20.25  ? 345 VAL B C      1 
ATOM   12608 O O      . VAL B 1 345 ? -10.739 31.711  -26.943 1.00 18.44  ? 345 VAL B O      1 
ATOM   12609 C CB     . VAL B 1 345 ? -8.373  32.829  -25.310 1.00 19.36  ? 345 VAL B CB     1 
ATOM   12610 C CG1    . VAL B 1 345 ? -8.459  34.308  -25.685 1.00 19.03  ? 345 VAL B CG1    1 
ATOM   12611 C CG2    . VAL B 1 345 ? -7.330  32.617  -24.219 1.00 18.53  ? 345 VAL B CG2    1 
ATOM   12612 H H      . VAL B 1 345 ? -9.395  30.403  -25.167 1.00 20.12  ? 345 VAL B H      1 
ATOM   12613 H HA     . VAL B 1 345 ? -10.034 32.825  -24.093 1.00 21.78  ? 345 VAL B HA     1 
ATOM   12614 H HB     . VAL B 1 345 ? -8.090  32.336  -26.096 1.00 23.24  ? 345 VAL B HB     1 
ATOM   12615 H HG11   . VAL B 1 345 ? -7.560  34.662  -25.775 1.00 22.84  ? 345 VAL B HG11   1 
ATOM   12616 H HG12   . VAL B 1 345 ? -8.934  34.397  -26.526 1.00 22.84  ? 345 VAL B HG12   1 
ATOM   12617 H HG13   . VAL B 1 345 ? -8.932  34.784  -24.984 1.00 22.84  ? 345 VAL B HG13   1 
ATOM   12618 H HG21   . VAL B 1 345 ? -6.483  32.983  -24.517 1.00 22.23  ? 345 VAL B HG21   1 
ATOM   12619 H HG22   . VAL B 1 345 ? -7.621  33.071  -23.412 1.00 22.23  ? 345 VAL B HG22   1 
ATOM   12620 H HG23   . VAL B 1 345 ? -7.239  31.666  -24.050 1.00 22.23  ? 345 VAL B HG23   1 
ATOM   12621 N N      . PHE B 1 346 ? -11.656 33.453  -25.835 1.00 17.80  ? 346 PHE B N      1 
ATOM   12622 C CA     . PHE B 1 346 ? -12.634 33.758  -26.877 1.00 20.26  ? 346 PHE B CA     1 
ATOM   12623 C C      . PHE B 1 346 ? -12.278 35.044  -27.612 1.00 22.87  ? 346 PHE B C      1 
ATOM   12624 O O      . PHE B 1 346 ? -12.227 36.112  -27.006 1.00 22.71  ? 346 PHE B O      1 
ATOM   12625 C CB     . PHE B 1 346 ? -14.038 33.894  -26.280 1.00 24.03  ? 346 PHE B CB     1 
ATOM   12626 C CG     . PHE B 1 346 ? -14.606 32.614  -25.751 1.00 25.27  ? 346 PHE B CG     1 
ATOM   12627 C CD1    . PHE B 1 346 ? -14.166 32.092  -24.548 1.00 23.62  ? 346 PHE B CD1    1 
ATOM   12628 C CD2    . PHE B 1 346 ? -15.600 31.941  -26.448 1.00 29.33  ? 346 PHE B CD2    1 
ATOM   12629 C CE1    . PHE B 1 346 ? -14.692 30.916  -24.059 1.00 24.00  ? 346 PHE B CE1    1 
ATOM   12630 C CE2    . PHE B 1 346 ? -16.131 30.770  -25.958 1.00 31.89  ? 346 PHE B CE2    1 
ATOM   12631 C CZ     . PHE B 1 346 ? -15.673 30.259  -24.748 1.00 24.22  ? 346 PHE B CZ     1 
ATOM   12632 H H      . PHE B 1 346 ? -11.718 33.956  -25.140 1.00 21.36  ? 346 PHE B H      1 
ATOM   12633 H HA     . PHE B 1 346 ? -12.658 33.039  -27.527 1.00 24.32  ? 346 PHE B HA     1 
ATOM   12634 H HB2    . PHE B 1 346 ? -14.003 34.527  -25.546 1.00 28.84  ? 346 PHE B HB2    1 
ATOM   12635 H HB3    . PHE B 1 346 ? -14.639 34.222  -26.967 1.00 28.84  ? 346 PHE B HB3    1 
ATOM   12636 H HD1    . PHE B 1 346 ? -13.501 32.533  -24.070 1.00 28.34  ? 346 PHE B HD1    1 
ATOM   12637 H HD2    . PHE B 1 346 ? -15.909 32.284  -27.255 1.00 35.19  ? 346 PHE B HD2    1 
ATOM   12638 H HE1    . PHE B 1 346 ? -14.387 30.574  -23.250 1.00 28.80  ? 346 PHE B HE1    1 
ATOM   12639 H HE2    . PHE B 1 346 ? -16.795 30.323  -26.432 1.00 38.27  ? 346 PHE B HE2    1 
ATOM   12640 H HZ     . PHE B 1 346 ? -16.025 29.465  -24.415 1.00 29.06  ? 346 PHE B HZ     1 
ATOM   12641 N N      . LEU B 1 347 ? -12.022 34.943  -28.912 1.00 21.59  ? 347 LEU B N      1 
ATOM   12642 C CA     . LEU B 1 347 ? -11.833 36.129  -29.743 1.00 21.70  ? 347 LEU B CA     1 
ATOM   12643 C C      . LEU B 1 347 ? -13.187 36.709  -30.140 1.00 22.18  ? 347 LEU B C      1 
ATOM   12644 O O      . LEU B 1 347 ? -14.088 35.975  -30.512 1.00 21.40  ? 347 LEU B O      1 
ATOM   12645 C CB     . LEU B 1 347 ? -11.038 35.796  -31.011 1.00 23.31  ? 347 LEU B CB     1 
ATOM   12646 C CG     . LEU B 1 347 ? -9.715  35.055  -30.870 1.00 22.23  ? 347 LEU B CG     1 
ATOM   12647 C CD1    . LEU B 1 347 ? -9.184  34.716  -32.253 1.00 22.98  ? 347 LEU B CD1    1 
ATOM   12648 C CD2    . LEU B 1 347 ? -8.699  35.869  -30.109 1.00 24.98  ? 347 LEU B CD2    1 
ATOM   12649 H H      . LEU B 1 347 ? -11.952 34.199  -29.338 1.00 25.91  ? 347 LEU B H      1 
ATOM   12650 H HA     . LEU B 1 347 ? -11.344 36.802  -29.245 1.00 26.04  ? 347 LEU B HA     1 
ATOM   12651 H HB2    . LEU B 1 347 ? -11.604 35.252  -31.580 1.00 27.98  ? 347 LEU B HB2    1 
ATOM   12652 H HB3    . LEU B 1 347 ? -10.844 36.631  -31.466 1.00 27.98  ? 347 LEU B HB3    1 
ATOM   12653 H HG     . LEU B 1 347 ? -9.862  34.226  -30.389 1.00 26.67  ? 347 LEU B HG     1 
ATOM   12654 H HD11   . LEU B 1 347 ? -8.355  34.222  -32.160 1.00 27.58  ? 347 LEU B HD11   1 
ATOM   12655 H HD12   . LEU B 1 347 ? -9.841  34.175  -32.719 1.00 27.58  ? 347 LEU B HD12   1 
ATOM   12656 H HD13   . LEU B 1 347 ? -9.026  35.539  -32.741 1.00 27.58  ? 347 LEU B HD13   1 
ATOM   12657 H HD21   . LEU B 1 347 ? -7.868  35.371  -30.061 1.00 29.97  ? 347 LEU B HD21   1 
ATOM   12658 H HD22   . LEU B 1 347 ? -8.556  36.709  -30.573 1.00 29.97  ? 347 LEU B HD22   1 
ATOM   12659 H HD23   . LEU B 1 347 ? -9.036  36.038  -29.215 1.00 29.97  ? 347 LEU B HD23   1 
ATOM   12660 N N      . ASP B 1 348 ? -13.323 38.029  -30.079 1.00 23.48  ? 348 ASP B N      1 
ATOM   12661 C CA     . ASP B 1 348 ? -14.533 38.694  -30.562 1.00 23.29  ? 348 ASP B CA     1 
ATOM   12662 C C      . ASP B 1 348 ? -14.315 38.991  -32.036 1.00 20.69  ? 348 ASP B C      1 
ATOM   12663 O O      . ASP B 1 348 ? -13.655 39.959  -32.380 1.00 19.93  ? 348 ASP B O      1 
ATOM   12664 C CB     . ASP B 1 348 ? -14.804 39.974  -29.767 1.00 24.26  ? 348 ASP B CB     1 
ATOM   12665 C CG     . ASP B 1 348 ? -16.078 40.690  -30.204 1.00 30.43  ? 348 ASP B CG     1 
ATOM   12666 O OD1    . ASP B 1 348 ? -16.654 40.350  -31.264 1.00 25.48  ? 348 ASP B OD1    1 
ATOM   12667 O OD2    . ASP B 1 348 ? -16.503 41.607  -29.466 1.00 28.64  ? 348 ASP B OD2    1 
ATOM   12668 H H      . ASP B 1 348 ? -12.730 38.565  -29.762 1.00 28.17  ? 348 ASP B H      1 
ATOM   12669 H HA     . ASP B 1 348 ? -15.299 38.107  -30.471 1.00 27.94  ? 348 ASP B HA     1 
ATOM   12670 H HB2    . ASP B 1 348 ? -14.896 39.748  -28.828 1.00 29.11  ? 348 ASP B HB2    1 
ATOM   12671 H HB3    . ASP B 1 348 ? -14.060 40.585  -29.889 1.00 29.11  ? 348 ASP B HB3    1 
ATOM   12672 N N      . ALA B 1 349 ? -14.847 38.138  -32.900 1.00 22.44  ? 349 ALA B N      1 
ATOM   12673 C CA     . ALA B 1 349 ? -14.579 38.242  -34.325 1.00 21.90  ? 349 ALA B CA     1 
ATOM   12674 C C      . ALA B 1 349 ? -15.293 39.438  -34.931 1.00 21.60  ? 349 ALA B C      1 
ATOM   12675 O O      . ALA B 1 349 ? -14.850 39.983  -35.951 1.00 24.35  ? 349 ALA B O      1 
ATOM   12676 C CB     . ALA B 1 349 ? -14.989 36.968  -35.030 1.00 20.71  ? 349 ALA B CB     1 
ATOM   12677 H H      . ALA B 1 349 ? -15.368 37.488  -32.685 1.00 26.93  ? 349 ALA B H      1 
ATOM   12678 H HA     . ALA B 1 349 ? -13.626 38.364  -34.459 1.00 26.28  ? 349 ALA B HA     1 
ATOM   12679 H HB1    . ALA B 1 349 ? -14.803 37.058  -35.978 1.00 24.85  ? 349 ALA B HB1    1 
ATOM   12680 H HB2    . ALA B 1 349 ? -14.483 36.227  -34.662 1.00 24.85  ? 349 ALA B HB2    1 
ATOM   12681 H HB3    . ALA B 1 349 ? -15.938 36.822  -34.891 1.00 24.85  ? 349 ALA B HB3    1 
ATOM   12682 N N      . ARG B 1 350 ? -16.400 39.842  -34.317 1.00 25.05  ? 350 ARG B N      1 
ATOM   12683 C CA     . ARG B 1 350 ? -17.109 41.038  -34.759 1.00 27.44  ? 350 ARG B CA     1 
ATOM   12684 C C      . ARG B 1 350 ? -16.190 42.255  -34.674 1.00 24.83  ? 350 ARG B C      1 
ATOM   12685 O O      . ARG B 1 350 ? -16.104 43.040  -35.615 1.00 24.34  ? 350 ARG B O      1 
ATOM   12686 C CB     . ARG B 1 350 ? -18.382 41.266  -33.928 1.00 28.57  ? 350 ARG B CB     1 
ATOM   12687 C CG     . ARG B 1 350 ? -19.150 42.512  -34.332 1.00 32.97  ? 350 ARG B CG     1 
ATOM   12688 C CD     . ARG B 1 350 ? -20.350 42.761  -33.434 1.00 33.96  ? 350 ARG B CD     1 
ATOM   12689 N NE     . ARG B 1 350 ? -21.448 41.821  -33.668 1.00 35.88  ? 350 ARG B NE     1 
ATOM   12690 C CZ     . ARG B 1 350 ? -21.773 40.809  -32.866 1.00 41.57  ? 350 ARG B CZ     1 
ATOM   12691 N NH1    . ARG B 1 350 ? -21.083 40.569  -31.753 1.00 37.89  ? 350 ARG B NH1    1 
ATOM   12692 N NH2    . ARG B 1 350 ? -22.803 40.033  -33.179 1.00 39.04  ? 350 ARG B NH2    1 
ATOM   12693 H H      . ARG B 1 350 ? -16.761 39.444  -33.646 1.00 30.06  ? 350 ARG B H      1 
ATOM   12694 H HA     . ARG B 1 350 ? -17.372 40.925  -35.686 1.00 32.93  ? 350 ARG B HA     1 
ATOM   12695 H HB2    . ARG B 1 350 ? -18.971 40.503  -34.039 1.00 34.28  ? 350 ARG B HB2    1 
ATOM   12696 H HB3    . ARG B 1 350 ? -18.137 41.361  -32.995 1.00 34.28  ? 350 ARG B HB3    1 
ATOM   12697 H HG2    . ARG B 1 350 ? -18.569 43.286  -34.270 1.00 39.57  ? 350 ARG B HG2    1 
ATOM   12698 H HG3    . ARG B 1 350 ? -19.470 42.407  -35.242 1.00 39.57  ? 350 ARG B HG3    1 
ATOM   12699 H HD2    . ARG B 1 350 ? -20.072 42.705  -32.510 1.00 40.75  ? 350 ARG B HD2    1 
ATOM   12700 H HD3    . ARG B 1 350 ? -20.688 43.652  -33.615 1.00 40.75  ? 350 ARG B HD3    1 
ATOM   12701 H HE     . ARG B 1 350 ? -21.920 41.931  -34.379 1.00 43.06  ? 350 ARG B HE     1 
ATOM   12702 H HH11   . ARG B 1 350 ? -20.416 41.064  -31.536 1.00 45.46  ? 350 ARG B HH11   1 
ATOM   12703 H HH12   . ARG B 1 350 ? -21.305 39.910  -31.248 1.00 45.46  ? 350 ARG B HH12   1 
ATOM   12704 H HH21   . ARG B 1 350 ? -23.251 40.182  -33.898 1.00 46.85  ? 350 ARG B HH21   1 
ATOM   12705 H HH22   . ARG B 1 350 ? -23.015 39.374  -32.669 1.00 46.85  ? 350 ARG B HH22   1 
ATOM   12706 N N      . ARG B 1 351 ? -15.485 42.401  -33.558 1.00 26.14  ? 351 ARG B N      1 
ATOM   12707 C CA     . ARG B 1 351 ? -14.613 43.557  -33.358 1.00 20.68  ? 351 ARG B CA     1 
ATOM   12708 C C      . ARG B 1 351 ? -13.236 43.371  -34.001 1.00 24.30  ? 351 ARG B C      1 
ATOM   12709 O O      . ARG B 1 351 ? -12.546 44.342  -34.294 1.00 23.16  ? 351 ARG B O      1 
ATOM   12710 C CB     . ARG B 1 351 ? -14.465 43.847  -31.864 1.00 25.65  ? 351 ARG B CB     1 
ATOM   12711 C CG     . ARG B 1 351 ? -15.710 44.462  -31.242 1.00 33.61  ? 351 ARG B CG     1 
ATOM   12712 C CD     . ARG B 1 351 ? -15.482 44.825  -29.786 1.00 40.47  ? 351 ARG B CD     1 
ATOM   12713 N NE     . ARG B 1 351 ? -14.495 45.895  -29.641 1.00 43.97  ? 351 ARG B NE     1 
ATOM   12714 C CZ     . ARG B 1 351 ? -13.671 46.028  -28.606 1.00 51.51  ? 351 ARG B CZ     1 
ATOM   12715 N NH1    . ARG B 1 351 ? -13.690 45.154  -27.605 1.00 51.06  ? 351 ARG B NH1    1 
ATOM   12716 N NH2    . ARG B 1 351 ? -12.814 47.039  -28.576 1.00 56.30  ? 351 ARG B NH2    1 
ATOM   12717 H H      . ARG B 1 351 ? -15.492 41.847  -32.901 1.00 31.37  ? 351 ARG B H      1 
ATOM   12718 H HA     . ARG B 1 351 ? -15.025 44.335  -33.766 1.00 24.81  ? 351 ARG B HA     1 
ATOM   12719 H HB2    . ARG B 1 351 ? -14.280 43.016  -31.400 1.00 30.79  ? 351 ARG B HB2    1 
ATOM   12720 H HB3    . ARG B 1 351 ? -13.730 44.467  -31.736 1.00 30.79  ? 351 ARG B HB3    1 
ATOM   12721 H HG2    . ARG B 1 351 ? -15.943 45.271  -31.724 1.00 40.33  ? 351 ARG B HG2    1 
ATOM   12722 H HG3    . ARG B 1 351 ? -16.439 43.823  -31.286 1.00 40.33  ? 351 ARG B HG3    1 
ATOM   12723 H HD2    . ARG B 1 351 ? -16.318 45.128  -29.397 1.00 48.56  ? 351 ARG B HD2    1 
ATOM   12724 H HD3    . ARG B 1 351 ? -15.160 44.039  -29.319 1.00 48.56  ? 351 ARG B HD3    1 
ATOM   12725 H HE     . ARG B 1 351 ? -14.444 46.479  -30.270 1.00 52.77  ? 351 ARG B HE     1 
ATOM   12726 H HH11   . ARG B 1 351 ? -14.241 44.495  -27.612 1.00 61.28  ? 351 ARG B HH11   1 
ATOM   12727 H HH12   . ARG B 1 351 ? -13.150 45.252  -26.943 1.00 61.28  ? 351 ARG B HH12   1 
ATOM   12728 H HH21   . ARG B 1 351 ? -12.796 47.606  -29.222 1.00 67.56  ? 351 ARG B HH21   1 
ATOM   12729 H HH22   . ARG B 1 351 ? -12.277 47.128  -27.910 1.00 67.56  ? 351 ARG B HH22   1 
ATOM   12730 N N      . PHE B 1 352 ? -12.842 42.119  -34.215 1.00 24.32  ? 352 PHE B N      1 
ATOM   12731 C CA     . PHE B 1 352 ? -11.606 41.795  -34.927 1.00 22.03  ? 352 PHE B CA     1 
ATOM   12732 C C      . PHE B 1 352 ? -11.711 42.210  -36.403 1.00 21.43  ? 352 PHE B C      1 
ATOM   12733 O O      . PHE B 1 352 ? -10.726 42.616  -37.019 1.00 21.23  ? 352 PHE B O      1 
ATOM   12734 C CB     . PHE B 1 352 ? -11.337 40.288  -34.804 1.00 17.93  ? 352 PHE B CB     1 
ATOM   12735 C CG     . PHE B 1 352 ? -9.912  39.867  -35.064 1.00 18.47  ? 352 PHE B CG     1 
ATOM   12736 C CD1    . PHE B 1 352 ? -9.374  39.902  -36.342 1.00 21.82  ? 352 PHE B CD1    1 
ATOM   12737 C CD2    . PHE B 1 352 ? -9.133  39.354  -34.030 1.00 20.53  ? 352 PHE B CD2    1 
ATOM   12738 C CE1    . PHE B 1 352 ? -8.061  39.483  -36.578 1.00 22.65  ? 352 PHE B CE1    1 
ATOM   12739 C CE2    . PHE B 1 352 ? -7.823  38.931  -34.261 1.00 20.41  ? 352 PHE B CE2    1 
ATOM   12740 C CZ     . PHE B 1 352 ? -7.290  38.990  -35.530 1.00 21.14  ? 352 PHE B CZ     1 
ATOM   12741 H H      . PHE B 1 352 ? -13.279 41.426  -33.953 1.00 29.18  ? 352 PHE B H      1 
ATOM   12742 H HA     . PHE B 1 352 ? -10.865 42.274  -34.524 1.00 26.43  ? 352 PHE B HA     1 
ATOM   12743 H HB2    . PHE B 1 352 ? -11.564 40.007  -33.904 1.00 21.52  ? 352 PHE B HB2    1 
ATOM   12744 H HB3    . PHE B 1 352 ? -11.900 39.821  -35.441 1.00 21.52  ? 352 PHE B HB3    1 
ATOM   12745 H HD1    . PHE B 1 352 ? -9.884  40.231  -37.046 1.00 26.18  ? 352 PHE B HD1    1 
ATOM   12746 H HD2    . PHE B 1 352 ? -9.484  39.311  -33.170 1.00 24.64  ? 352 PHE B HD2    1 
ATOM   12747 H HE1    . PHE B 1 352 ? -7.706  39.525  -37.437 1.00 27.18  ? 352 PHE B HE1    1 
ATOM   12748 H HE2    . PHE B 1 352 ? -7.310  38.605  -33.557 1.00 24.49  ? 352 PHE B HE2    1 
ATOM   12749 H HZ     . PHE B 1 352 ? -6.416  38.711  -35.683 1.00 25.36  ? 352 PHE B HZ     1 
ATOM   12750 N N      . CYS B 1 353 ? -12.915 42.097  -36.960 1.00 22.52  ? 353 CYS B N      1 
ATOM   12751 C CA     . CYS B 1 353 ? -13.160 42.400  -38.369 1.00 21.18  ? 353 CYS B CA     1 
ATOM   12752 C C      . CYS B 1 353 ? -14.236 43.469  -38.536 1.00 20.54  ? 353 CYS B C      1 
ATOM   12753 O O      . CYS B 1 353 ? -15.316 43.177  -39.053 1.00 22.27  ? 353 CYS B O      1 
ATOM   12754 C CB     . CYS B 1 353 ? -13.591 41.143  -39.114 1.00 22.87  ? 353 CYS B CB     1 
ATOM   12755 S SG     . CYS B 1 353 ? -12.455 39.722  -38.931 1.00 24.77  ? 353 CYS B SG     1 
ATOM   12756 H H      . CYS B 1 353 ? -13.618 41.842  -36.536 1.00 27.02  ? 353 CYS B H      1 
ATOM   12757 H HA     . CYS B 1 353 ? -12.347 42.726  -38.785 1.00 25.42  ? 353 CYS B HA     1 
ATOM   12758 H HB2    . CYS B 1 353 ? -14.457 40.863  -38.779 1.00 27.44  ? 353 CYS B HB2    1 
ATOM   12759 H HB3    . CYS B 1 353 ? -13.656 41.349  -40.060 1.00 27.44  ? 353 CYS B HB3    1 
ATOM   12760 H HG     . CYS B 1 353 ? -12.888 38.793  -39.554 1.00 29.73  ? 353 CYS B HG     1 
ATOM   12761 N N      . PRO B 1 354 ? -13.943 44.707  -38.113 1.00 21.85  ? 354 PRO B N      1 
ATOM   12762 C CA     . PRO B 1 354 ? -14.962 45.768  -38.112 1.00 26.32  ? 354 PRO B CA     1 
ATOM   12763 C C      . PRO B 1 354 ? -15.443 46.144  -39.513 1.00 25.39  ? 354 PRO B C      1 
ATOM   12764 O O      . PRO B 1 354 ? -16.512 46.726  -39.677 1.00 23.66  ? 354 PRO B O      1 
ATOM   12765 C CB     . PRO B 1 354 ? -14.237 46.942  -37.453 1.00 28.60  ? 354 PRO B CB     1 
ATOM   12766 C CG     . PRO B 1 354 ? -12.798 46.703  -37.729 1.00 26.78  ? 354 PRO B CG     1 
ATOM   12767 C CD     . PRO B 1 354 ? -12.628 45.209  -37.673 1.00 22.50  ? 354 PRO B CD     1 
ATOM   12768 H HA     . PRO B 1 354 ? -15.721 45.509  -37.567 1.00 31.59  ? 354 PRO B HA     1 
ATOM   12769 H HB2    . PRO B 1 354 ? -14.530 47.775  -37.854 1.00 34.32  ? 354 PRO B HB2    1 
ATOM   12770 H HB3    . PRO B 1 354 ? -14.409 46.939  -36.498 1.00 34.32  ? 354 PRO B HB3    1 
ATOM   12771 H HG2    . PRO B 1 354 ? -12.574 47.041  -38.610 1.00 32.13  ? 354 PRO B HG2    1 
ATOM   12772 H HG3    . PRO B 1 354 ? -12.259 47.135  -37.048 1.00 32.13  ? 354 PRO B HG3    1 
ATOM   12773 H HD2    . PRO B 1 354 ? -11.933 44.925  -38.287 1.00 27.00  ? 354 PRO B HD2    1 
ATOM   12774 H HD3    . PRO B 1 354 ? -12.441 44.923  -36.766 1.00 27.00  ? 354 PRO B HD3    1 
ATOM   12775 N N      . HIS B 1 355 ? -14.638 45.802  -40.510 1.00 25.32  ? 355 HIS B N      1 
ATOM   12776 C CA     . HIS B 1 355 ? -14.966 46.041  -41.911 1.00 26.75  ? 355 HIS B CA     1 
ATOM   12777 C C      . HIS B 1 355 ? -15.995 45.053  -42.462 1.00 24.53  ? 355 HIS B C      1 
ATOM   12778 O O      . HIS B 1 355 ? -16.544 45.273  -43.541 1.00 24.22  ? 355 HIS B O      1 
ATOM   12779 C CB     . HIS B 1 355 ? -13.690 45.981  -42.749 1.00 28.30  ? 355 HIS B CB     1 
ATOM   12780 C CG     . HIS B 1 355 ? -13.005 44.650  -42.695 1.00 27.07  ? 355 HIS B CG     1 
ATOM   12781 N ND1    . HIS B 1 355 ? -12.400 44.175  -41.551 1.00 21.58  ? 355 HIS B ND1    1 
ATOM   12782 C CD2    . HIS B 1 355 ? -12.855 43.686  -43.634 1.00 26.71  ? 355 HIS B CD2    1 
ATOM   12783 C CE1    . HIS B 1 355 ? -11.902 42.972  -41.790 1.00 26.87  ? 355 HIS B CE1    1 
ATOM   12784 N NE2    . HIS B 1 355 ? -12.161 42.653  -43.043 1.00 26.85  ? 355 HIS B NE2    1 
ATOM   12785 H H      . HIS B 1 355 ? -13.876 45.428  -40.393 1.00 30.39  ? 355 HIS B H      1 
ATOM   12786 H HA     . HIS B 1 355 ? -15.336 46.933  -41.998 1.00 32.10  ? 355 HIS B HA     1 
ATOM   12787 H HB2    . HIS B 1 355 ? -13.914 46.163  -43.675 1.00 33.96  ? 355 HIS B HB2    1 
ATOM   12788 H HB3    . HIS B 1 355 ? -13.068 46.650  -42.422 1.00 33.96  ? 355 HIS B HB3    1 
ATOM   12789 H HD2    . HIS B 1 355 ? -13.162 43.716  -44.511 1.00 32.06  ? 355 HIS B HD2    1 
ATOM   12790 H HE1    . HIS B 1 355 ? -11.440 42.444  -41.180 1.00 32.24  ? 355 HIS B HE1    1 
ATOM   12791 H HE2    . HIS B 1 355 ? -11.930 41.920  -43.430 1.00 32.22  ? 355 HIS B HE2    1 
ATOM   12792 N N      . LEU B 1 356 ? -16.270 43.973  -41.728 1.00 22.87  ? 356 LEU B N      1 
ATOM   12793 C CA     . LEU B 1 356 ? -17.255 42.981  -42.163 1.00 21.75  ? 356 LEU B CA     1 
ATOM   12794 C C      . LEU B 1 356 ? -18.562 43.116  -41.392 1.00 23.95  ? 356 LEU B C      1 
ATOM   12795 O O      . LEU B 1 356 ? -18.592 43.677  -40.298 1.00 25.35  ? 356 LEU B O      1 
ATOM   12796 C CB     . LEU B 1 356 ? -16.712 41.553  -41.992 1.00 23.01  ? 356 LEU B CB     1 
ATOM   12797 C CG     . LEU B 1 356 ? -15.434 41.204  -42.743 1.00 19.82  ? 356 LEU B CG     1 
ATOM   12798 C CD1    . LEU B 1 356 ? -15.010 39.787  -42.388 1.00 21.30  ? 356 LEU B CD1    1 
ATOM   12799 C CD2    . LEU B 1 356 ? -15.633 41.355  -44.253 1.00 23.69  ? 356 LEU B CD2    1 
ATOM   12800 H H      . LEU B 1 356 ? -15.900 43.790  -40.974 1.00 27.45  ? 356 LEU B H      1 
ATOM   12801 H HA     . LEU B 1 356 ? -17.454 43.107  -43.103 1.00 26.11  ? 356 LEU B HA     1 
ATOM   12802 H HB2    . LEU B 1 356 ? -16.538 41.408  -41.049 1.00 27.61  ? 356 LEU B HB2    1 
ATOM   12803 H HB3    . LEU B 1 356 ? -17.396 40.933  -42.289 1.00 27.61  ? 356 LEU B HB3    1 
ATOM   12804 H HG     . LEU B 1 356 ? -14.727 41.809  -42.468 1.00 23.79  ? 356 LEU B HG     1 
ATOM   12805 H HD11   . LEU B 1 356 ? -14.196 39.571  -42.870 1.00 25.56  ? 356 LEU B HD11   1 
ATOM   12806 H HD12   . LEU B 1 356 ? -14.852 39.735  -41.432 1.00 25.56  ? 356 LEU B HD12   1 
ATOM   12807 H HD13   . LEU B 1 356 ? -15.717 39.173  -42.641 1.00 25.56  ? 356 LEU B HD13   1 
ATOM   12808 H HD21   . LEU B 1 356 ? -14.836 41.043  -44.709 1.00 28.43  ? 356 LEU B HD21   1 
ATOM   12809 H HD22   . LEU B 1 356 ? -16.399 40.825  -44.524 1.00 28.43  ? 356 LEU B HD22   1 
ATOM   12810 H HD23   . LEU B 1 356 ? -15.788 42.290  -44.460 1.00 28.43  ? 356 LEU B HD23   1 
ATOM   12811 N N      . THR B 1 357 ? -19.644 42.617  -41.979 1.00 20.11  ? 357 THR B N      1 
ATOM   12812 C CA     . THR B 1 357 ? -20.902 42.447  -41.254 1.00 25.70  ? 357 THR B CA     1 
ATOM   12813 C C      . THR B 1 357 ? -20.979 41.011  -40.758 1.00 28.78  ? 357 THR B C      1 
ATOM   12814 O O      . THR B 1 357 ? -20.281 40.141  -41.269 1.00 24.66  ? 357 THR B O      1 
ATOM   12815 C CB     . THR B 1 357 ? -22.138 42.730  -42.124 1.00 31.77  ? 357 THR B CB     1 
ATOM   12816 O OG1    . THR B 1 357 ? -22.295 41.679  -43.086 1.00 32.99  ? 357 THR B OG1    1 
ATOM   12817 C CG2    . THR B 1 357 ? -22.017 44.068  -42.825 1.00 30.15  ? 357 THR B CG2    1 
ATOM   12818 H H      . THR B 1 357 ? -19.678 42.367  -42.801 1.00 24.14  ? 357 THR B H      1 
ATOM   12819 H HA     . THR B 1 357 ? -20.929 43.040  -40.487 1.00 30.84  ? 357 THR B HA     1 
ATOM   12820 H HB     . THR B 1 357 ? -22.924 42.759  -41.556 1.00 38.12  ? 357 THR B HB     1 
ATOM   12821 H HG1    . THR B 1 357 ? -22.971 41.825  -43.563 1.00 39.59  ? 357 THR B HG1    1 
ATOM   12822 H HG21   . THR B 1 357 ? -22.831 44.259  -43.316 1.00 36.18  ? 357 THR B HG21   1 
ATOM   12823 H HG22   . THR B 1 357 ? -21.869 44.771  -42.173 1.00 36.18  ? 357 THR B HG22   1 
ATOM   12824 H HG23   . THR B 1 357 ? -21.272 44.052  -43.445 1.00 36.18  ? 357 THR B HG23   1 
ATOM   12825 N N      . GLN B 1 358 ? -21.837 40.754  -39.779 1.00 28.79  ? 358 GLN B N      1 
ATOM   12826 C CA     . GLN B 1 358 ? -21.988 39.399  -39.266 1.00 31.11  ? 358 GLN B CA     1 
ATOM   12827 C C      . GLN B 1 358 ? -22.514 38.468  -40.350 1.00 28.99  ? 358 GLN B C      1 
ATOM   12828 O O      . GLN B 1 358 ? -22.268 37.266  -40.310 1.00 24.62  ? 358 GLN B O      1 
ATOM   12829 C CB     . GLN B 1 358 ? -22.923 39.372  -38.054 1.00 34.84  ? 358 GLN B CB     1 
ATOM   12830 C CG     . GLN B 1 358 ? -22.955 38.018  -37.332 1.00 32.35  ? 358 GLN B CG     1 
ATOM   12831 C CD     . GLN B 1 358 ? -23.781 38.062  -36.060 1.00 37.48  ? 358 GLN B CD     1 
ATOM   12832 O OE1    . GLN B 1 358 ? -24.757 38.804  -35.971 1.00 31.01  ? 358 GLN B OE1    1 
ATOM   12833 N NE2    . GLN B 1 358 ? -23.386 37.274  -35.063 1.00 30.36  ? 358 GLN B NE2    1 
ATOM   12834 H H      . GLN B 1 358 ? -22.339 41.339  -39.398 1.00 34.55  ? 358 GLN B H      1 
ATOM   12835 H HA     . GLN B 1 358 ? -21.121 39.070  -38.983 1.00 37.33  ? 358 GLN B HA     1 
ATOM   12836 H HB2    . GLN B 1 358 ? -22.630 40.042  -37.417 1.00 41.80  ? 358 GLN B HB2    1 
ATOM   12837 H HB3    . GLN B 1 358 ? -23.824 39.571  -38.351 1.00 41.80  ? 358 GLN B HB3    1 
ATOM   12838 H HG2    . GLN B 1 358 ? -23.345 37.353  -37.920 1.00 38.82  ? 358 GLN B HG2    1 
ATOM   12839 H HG3    . GLN B 1 358 ? -22.050 37.763  -37.095 1.00 38.82  ? 358 GLN B HG3    1 
ATOM   12840 H HE21   . GLN B 1 358 ? -22.693 36.773  -35.159 1.00 36.44  ? 358 GLN B HE21   1 
ATOM   12841 H HE22   . GLN B 1 358 ? -23.823 37.265  -34.323 1.00 36.44  ? 358 GLN B HE22   1 
ATOM   12842 N N      . ASP B 1 359 ? -23.225 39.020  -41.331 1.00 25.58  ? 359 ASP B N      1 
ATOM   12843 C CA     . ASP B 1 359 ? -23.785 38.193  -42.393 1.00 26.39  ? 359 ASP B CA     1 
ATOM   12844 C C      . ASP B 1 359 ? -22.711 37.736  -43.381 1.00 22.63  ? 359 ASP B C      1 
ATOM   12845 O O      . ASP B 1 359 ? -22.980 36.930  -44.266 1.00 24.65  ? 359 ASP B O      1 
ATOM   12846 C CB     . ASP B 1 359 ? -24.909 38.934  -43.119 1.00 32.48  ? 359 ASP B CB     1 
ATOM   12847 C CG     . ASP B 1 359 ? -26.259 38.731  -42.443 1.00 34.81  ? 359 ASP B CG     1 
ATOM   12848 O OD1    . ASP B 1 359 ? -26.379 39.043  -41.238 1.00 37.74  ? 359 ASP B OD1    1 
ATOM   12849 O OD2    . ASP B 1 359 ? -27.190 38.223  -43.097 1.00 38.78  ? 359 ASP B OD2    1 
ATOM   12850 H H      . ASP B 1 359 ? -23.396 39.860  -41.404 1.00 30.69  ? 359 ASP B H      1 
ATOM   12851 H HA     . ASP B 1 359 ? -24.172 37.398  -41.994 1.00 31.67  ? 359 ASP B HA     1 
ATOM   12852 H HB2    . ASP B 1 359 ? -24.713 39.884  -43.123 1.00 38.97  ? 359 ASP B HB2    1 
ATOM   12853 H HB3    . ASP B 1 359 ? -24.974 38.602  -44.028 1.00 38.97  ? 359 ASP B HB3    1 
ATOM   12854 N N      . GLU B 1 360 ? -21.497 38.246  -43.207 1.00 23.95  ? 360 GLU B N      1 
ATOM   12855 C CA     . GLU B 1 360 ? -20.345 37.768  -43.963 1.00 25.13  ? 360 GLU B CA     1 
ATOM   12856 C C      . GLU B 1 360 ? -19.498 36.799  -43.125 1.00 22.26  ? 360 GLU B C      1 
ATOM   12857 O O      . GLU B 1 360 ? -18.401 36.425  -43.528 1.00 21.83  ? 360 GLU B O      1 
ATOM   12858 C CB     . GLU B 1 360 ? -19.509 38.957  -44.439 1.00 26.18  ? 360 GLU B CB     1 
ATOM   12859 C CG     . GLU B 1 360 ? -20.243 39.779  -45.487 1.00 32.70  ? 360 GLU B CG     1 
ATOM   12860 C CD     . GLU B 1 360 ? -19.581 41.111  -45.792 1.00 41.30  ? 360 GLU B CD     1 
ATOM   12861 O OE1    . GLU B 1 360 ? -19.347 41.912  -44.853 1.00 32.12  ? 360 GLU B OE1    1 
ATOM   12862 O OE2    . GLU B 1 360 ? -19.308 41.359  -46.986 1.00 46.96  ? 360 GLU B OE2    1 
ATOM   12863 H H      . GLU B 1 360 ? -21.309 38.878  -42.655 1.00 28.74  ? 360 GLU B H      1 
ATOM   12864 H HA     . GLU B 1 360 ? -20.647 37.291  -44.751 1.00 30.16  ? 360 GLU B HA     1 
ATOM   12865 H HB2    . GLU B 1 360 ? -19.314 39.533  -43.683 1.00 31.42  ? 360 GLU B HB2    1 
ATOM   12866 H HB3    . GLU B 1 360 ? -18.685 38.631  -44.833 1.00 31.42  ? 360 GLU B HB3    1 
ATOM   12867 H HG2    . GLU B 1 360 ? -20.281 39.271  -46.312 1.00 39.24  ? 360 GLU B HG2    1 
ATOM   12868 H HG3    . GLU B 1 360 ? -21.142 39.960  -45.170 1.00 39.24  ? 360 GLU B HG3    1 
ATOM   12869 N N      . PHE B 1 361 ? -20.024 36.411  -41.964 1.00 19.71  ? 361 PHE B N      1 
ATOM   12870 C CA     . PHE B 1 361 ? -19.460 35.331  -41.140 1.00 21.28  ? 361 PHE B CA     1 
ATOM   12871 C C      . PHE B 1 361 ? -18.014 35.581  -40.688 1.00 23.37  ? 361 PHE B C      1 
ATOM   12872 O O      . PHE B 1 361 ? -17.118 34.782  -40.979 1.00 21.64  ? 361 PHE B O      1 
ATOM   12873 C CB     . PHE B 1 361 ? -19.533 34.017  -41.912 1.00 22.25  ? 361 PHE B CB     1 
ATOM   12874 C CG     . PHE B 1 361 ? -20.868 33.771  -42.573 1.00 23.63  ? 361 PHE B CG     1 
ATOM   12875 C CD1    . PHE B 1 361 ? -22.055 34.211  -41.988 1.00 21.97  ? 361 PHE B CD1    1 
ATOM   12876 C CD2    . PHE B 1 361 ? -20.934 33.101  -43.785 1.00 23.15  ? 361 PHE B CD2    1 
ATOM   12877 C CE1    . PHE B 1 361 ? -23.277 33.977  -42.605 1.00 24.34  ? 361 PHE B CE1    1 
ATOM   12878 C CE2    . PHE B 1 361 ? -22.153 32.862  -44.403 1.00 23.50  ? 361 PHE B CE2    1 
ATOM   12879 C CZ     . PHE B 1 361 ? -23.326 33.308  -43.814 1.00 25.78  ? 361 PHE B CZ     1 
ATOM   12880 H H      . PHE B 1 361 ? -20.726 36.764  -41.616 1.00 23.66  ? 361 PHE B H      1 
ATOM   12881 H HA     . PHE B 1 361 ? -20.003 35.235  -40.342 1.00 25.53  ? 361 PHE B HA     1 
ATOM   12882 H HB2    . PHE B 1 361 ? -18.859 34.023  -42.609 1.00 26.70  ? 361 PHE B HB2    1 
ATOM   12883 H HB3    . PHE B 1 361 ? -19.366 33.284  -41.299 1.00 26.70  ? 361 PHE B HB3    1 
ATOM   12884 H HD1    . PHE B 1 361 ? -22.028 34.663  -41.176 1.00 26.36  ? 361 PHE B HD1    1 
ATOM   12885 H HD2    . PHE B 1 361 ? -20.150 32.801  -44.186 1.00 27.78  ? 361 PHE B HD2    1 
ATOM   12886 H HE1    . PHE B 1 361 ? -24.063 34.275  -42.207 1.00 29.21  ? 361 PHE B HE1    1 
ATOM   12887 H HE2    . PHE B 1 361 ? -22.182 32.412  -45.217 1.00 28.20  ? 361 PHE B HE2    1 
ATOM   12888 H HZ     . PHE B 1 361 ? -24.144 33.150  -44.227 1.00 30.94  ? 361 PHE B HZ     1 
ATOM   12889 N N      . PRO B 1 362 ? -17.782 36.683  -39.957 1.00 20.05  ? 362 PRO B N      1 
ATOM   12890 C CA     . PRO B 1 362 ? -16.416 37.025  -39.546 1.00 19.77  ? 362 PRO B CA     1 
ATOM   12891 C C      . PRO B 1 362 ? -15.781 35.971  -38.626 1.00 19.15  ? 362 PRO B C      1 
ATOM   12892 O O      . PRO B 1 362 ? -14.589 35.708  -38.788 1.00 21.19  ? 362 PRO B O      1 
ATOM   12893 C CB     . PRO B 1 362 ? -16.588 38.373  -38.838 1.00 22.86  ? 362 PRO B CB     1 
ATOM   12894 C CG     . PRO B 1 362 ? -18.011 38.408  -38.431 1.00 27.16  ? 362 PRO B CG     1 
ATOM   12895 C CD     . PRO B 1 362 ? -18.772 37.647  -39.455 1.00 23.83  ? 362 PRO B CD     1 
ATOM   12896 H HA     . PRO B 1 362 ? -15.853 37.146  -40.327 1.00 23.72  ? 362 PRO B HA     1 
ATOM   12897 H HB2    . PRO B 1 362 ? -16.007 38.412  -38.062 1.00 27.43  ? 362 PRO B HB2    1 
ATOM   12898 H HB3    . PRO B 1 362 ? -16.389 39.095  -39.455 1.00 27.43  ? 362 PRO B HB3    1 
ATOM   12899 H HG2    . PRO B 1 362 ? -18.105 37.989  -37.562 1.00 32.60  ? 362 PRO B HG2    1 
ATOM   12900 H HG3    . PRO B 1 362 ? -18.315 39.329  -38.398 1.00 32.60  ? 362 PRO B HG3    1 
ATOM   12901 H HD2    . PRO B 1 362 ? -19.521 37.185  -39.047 1.00 28.59  ? 362 PRO B HD2    1 
ATOM   12902 H HD3    . PRO B 1 362 ? -19.062 38.235  -40.169 1.00 28.59  ? 362 PRO B HD3    1 
ATOM   12903 N N      . ALA B 1 363 ? -16.536 35.361  -37.713 1.00 18.68  ? 363 ALA B N      1 
ATOM   12904 C CA     . ALA B 1 363 ? -15.961 34.308  -36.873 1.00 21.07  ? 363 ALA B CA     1 
ATOM   12905 C C      . ALA B 1 363 ? -15.498 33.124  -37.722 1.00 22.32  ? 363 ALA B C      1 
ATOM   12906 O O      . ALA B 1 363 ? -14.378 32.645  -37.553 1.00 18.48  ? 363 ALA B O      1 
ATOM   12907 C CB     . ALA B 1 363 ? -16.958 33.837  -35.805 1.00 21.61  ? 363 ALA B CB     1 
ATOM   12908 H H      . ALA B 1 363 ? -17.365 35.532  -37.561 1.00 22.42  ? 363 ALA B H      1 
ATOM   12909 H HA     . ALA B 1 363 ? -15.183 34.662  -36.416 1.00 25.28  ? 363 ALA B HA     1 
ATOM   12910 H HB1    . ALA B 1 363 ? -16.543 33.141  -35.272 1.00 25.93  ? 363 ALA B HB1    1 
ATOM   12911 H HB2    . ALA B 1 363 ? -17.194 34.590  -35.241 1.00 25.93  ? 363 ALA B HB2    1 
ATOM   12912 H HB3    . ALA B 1 363 ? -17.750 33.490  -36.244 1.00 25.93  ? 363 ALA B HB3    1 
ATOM   12913 N N      . GLN B 1 364 ? -16.351 32.663  -38.637 1.00 19.62  ? 364 GLN B N      1 
ATOM   12914 C CA     . GLN B 1 364 ? -16.006 31.526  -39.487 1.00 19.36  ? 364 GLN B CA     1 
ATOM   12915 C C      . GLN B 1 364 ? -14.767 31.851  -40.312 1.00 19.07  ? 364 GLN B C      1 
ATOM   12916 O O      . GLN B 1 364 ? -13.852 31.040  -40.417 1.00 18.08  ? 364 GLN B O      1 
ATOM   12917 C CB     . GLN B 1 364 ? -17.173 31.149  -40.408 1.00 19.90  ? 364 GLN B CB     1 
ATOM   12918 C CG     . GLN B 1 364 ? -17.041 29.764  -41.036 1.00 21.31  ? 364 GLN B CG     1 
ATOM   12919 C CD     . GLN B 1 364 ? -17.373 28.655  -40.047 1.00 23.64  ? 364 GLN B CD     1 
ATOM   12920 O OE1    . GLN B 1 364 ? -18.519 28.520  -39.621 1.00 27.71  ? 364 GLN B OE1    1 
ATOM   12921 N NE2    . GLN B 1 364 ? -16.365 27.878  -39.655 1.00 26.46  ? 364 GLN B NE2    1 
ATOM   12922 H H      . GLN B 1 364 ? -17.133 32.990  -38.784 1.00 23.55  ? 364 GLN B H      1 
ATOM   12923 H HA     . GLN B 1 364 ? -15.804 30.760  -38.927 1.00 23.23  ? 364 GLN B HA     1 
ATOM   12924 H HB2    . GLN B 1 364 ? -17.995 31.164  -39.893 1.00 23.88  ? 364 GLN B HB2    1 
ATOM   12925 H HB3    . GLN B 1 364 ? -17.225 31.797  -41.128 1.00 23.88  ? 364 GLN B HB3    1 
ATOM   12926 H HG2    . GLN B 1 364 ? -17.654 29.694  -41.785 1.00 25.57  ? 364 GLN B HG2    1 
ATOM   12927 H HG3    . GLN B 1 364 ? -16.128 29.636  -41.338 1.00 25.57  ? 364 GLN B HG3    1 
ATOM   12928 H HE21   . GLN B 1 364 ? -15.572 28.016  -39.959 1.00 31.76  ? 364 GLN B HE21   1 
ATOM   12929 H HE22   . GLN B 1 364 ? -16.507 27.239  -39.098 1.00 31.76  ? 364 GLN B HE22   1 
ATOM   12930 N N      . SER B 1 365 ? -14.715 33.061  -40.864 1.00 18.84  ? 365 SER B N      1 
ATOM   12931 C CA     . SER B 1 365 ? -13.596 33.439  -41.711 1.00 19.46  ? 365 SER B CA     1 
ATOM   12932 C C      . SER B 1 365 ? -12.304 33.612  -40.904 1.00 18.13  ? 365 SER B C      1 
ATOM   12933 O O      . SER B 1 365 ? -11.238 33.175  -41.335 1.00 18.70  ? 365 SER B O      1 
ATOM   12934 C CB     . SER B 1 365 ? -13.906 34.720  -42.484 1.00 21.50  ? 365 SER B CB     1 
ATOM   12935 O OG     . SER B 1 365 ? -12.850 34.997  -43.390 1.00 19.43  ? 365 SER B OG     1 
ATOM   12936 H H      . SER B 1 365 ? -15.310 33.673  -40.763 1.00 22.61  ? 365 SER B H      1 
ATOM   12937 H HA     . SER B 1 365 ? -13.446 32.734  -42.360 1.00 23.35  ? 365 SER B HA     1 
ATOM   12938 H HB2    . SER B 1 365 ? -14.731 34.602  -42.981 1.00 25.80  ? 365 SER B HB2    1 
ATOM   12939 H HB3    . SER B 1 365 ? -13.993 35.457  -41.859 1.00 25.80  ? 365 SER B HB3    1 
ATOM   12940 H HG     . SER B 1 365 ? -13.012 35.705  -43.812 1.00 23.32  ? 365 SER B HG     1 
ATOM   12941 N N      . LEU B 1 366 ? -12.394 34.224  -39.730 1.00 16.83  ? 366 LEU B N      1 
ATOM   12942 C CA     . LEU B 1 366 ? -11.221 34.377  -38.882 1.00 18.37  ? 366 LEU B CA     1 
ATOM   12943 C C      . LEU B 1 366 ? -10.660 33.004  -38.473 1.00 14.05  ? 366 LEU B C      1 
ATOM   12944 O O      . LEU B 1 366 ? -9.451  32.810  -38.496 1.00 17.15  ? 366 LEU B O      1 
ATOM   12945 C CB     . LEU B 1 366 ? -11.555 35.211  -37.642 1.00 16.55  ? 366 LEU B CB     1 
ATOM   12946 C CG     . LEU B 1 366 ? -10.450 35.409  -36.600 1.00 17.71  ? 366 LEU B CG     1 
ATOM   12947 C CD1    . LEU B 1 366 ? -9.203  36.030  -37.213 1.00 20.71  ? 366 LEU B CD1    1 
ATOM   12948 C CD2    . LEU B 1 366 ? -10.970 36.283  -35.444 1.00 17.92  ? 366 LEU B CD2    1 
ATOM   12949 H H      . LEU B 1 366 ? -13.117 34.557  -39.404 1.00 20.20  ? 366 LEU B H      1 
ATOM   12950 H HA     . LEU B 1 366 ? -10.532 34.845  -39.380 1.00 22.04  ? 366 LEU B HA     1 
ATOM   12951 H HB2    . LEU B 1 366 ? -11.826 36.094  -37.939 1.00 19.86  ? 366 LEU B HB2    1 
ATOM   12952 H HB3    . LEU B 1 366 ? -12.300 34.787  -37.188 1.00 19.86  ? 366 LEU B HB3    1 
ATOM   12953 H HG     . LEU B 1 366 ? -10.204 34.546  -36.233 1.00 21.25  ? 366 LEU B HG     1 
ATOM   12954 H HD11   . LEU B 1 366 ? -8.554  36.191  -36.511 1.00 24.85  ? 366 LEU B HD11   1 
ATOM   12955 H HD12   . LEU B 1 366 ? -8.835  35.418  -37.869 1.00 24.85  ? 366 LEU B HD12   1 
ATOM   12956 H HD13   . LEU B 1 366 ? -9.445  36.867  -37.639 1.00 24.85  ? 366 LEU B HD13   1 
ATOM   12957 H HD21   . LEU B 1 366 ? -10.260 36.400  -34.793 1.00 21.50  ? 366 LEU B HD21   1 
ATOM   12958 H HD22   . LEU B 1 366 ? -11.240 37.145  -35.797 1.00 21.50  ? 366 LEU B HD22   1 
ATOM   12959 H HD23   . LEU B 1 366 ? -11.729 35.841  -35.032 1.00 21.50  ? 366 LEU B HD23   1 
ATOM   12960 N N      . ALA B 1 367 ? -11.528 32.057  -38.126 1.00 17.73  ? 367 ALA B N      1 
ATOM   12961 C CA     . ALA B 1 367 ? -11.072 30.692  -37.810 1.00 18.09  ? 367 ALA B CA     1 
ATOM   12962 C C      . ALA B 1 367 ? -10.339 30.072  -38.998 1.00 18.18  ? 367 ALA B C      1 
ATOM   12963 O O      . ALA B 1 367 ? -9.296  29.439  -38.826 1.00 14.75  ? 367 ALA B O      1 
ATOM   12964 C CB     . ALA B 1 367 ? -12.240 29.811  -37.405 1.00 16.58  ? 367 ALA B CB     1 
ATOM   12965 H H      . ALA B 1 367 ? -12.378 32.171  -38.065 1.00 21.27  ? 367 ALA B H      1 
ATOM   12966 H HA     . ALA B 1 367 ? -10.454 30.731  -37.064 1.00 21.71  ? 367 ALA B HA     1 
ATOM   12967 H HB1    . ALA B 1 367 ? -11.909 28.922  -37.204 1.00 19.89  ? 367 ALA B HB1    1 
ATOM   12968 H HB2    . ALA B 1 367 ? -12.665 30.192  -36.621 1.00 19.89  ? 367 ALA B HB2    1 
ATOM   12969 H HB3    . ALA B 1 367 ? -12.874 29.771  -38.138 1.00 19.89  ? 367 ALA B HB3    1 
ATOM   12970 N N      . ALA B 1 368 ? -10.873 30.257  -40.205 1.00 15.22  ? 368 ALA B N      1 
ATOM   12971 C CA     . ALA B 1 368 ? -10.198 29.759  -41.392 1.00 15.76  ? 368 ALA B CA     1 
ATOM   12972 C C      . ALA B 1 368 ? -8.817  30.405  -41.551 1.00 17.98  ? 368 ALA B C      1 
ATOM   12973 O O      . ALA B 1 368 ? -7.835  29.716  -41.827 1.00 17.05  ? 368 ALA B O      1 
ATOM   12974 C CB     . ALA B 1 368 ? -11.052 30.001  -42.645 1.00 17.06  ? 368 ALA B CB     1 
ATOM   12975 H H      . ALA B 1 368 ? -11.616 30.663  -40.358 1.00 18.26  ? 368 ALA B H      1 
ATOM   12976 H HA     . ALA B 1 368 ? -10.069 28.802  -41.301 1.00 18.91  ? 368 ALA B HA     1 
ATOM   12977 H HB1    . ALA B 1 368 ? -10.580 29.658  -43.420 1.00 20.48  ? 368 ALA B HB1    1 
ATOM   12978 H HB2    . ALA B 1 368 ? -11.899 29.540  -42.543 1.00 20.48  ? 368 ALA B HB2    1 
ATOM   12979 H HB3    . ALA B 1 368 ? -11.203 30.954  -42.745 1.00 20.48  ? 368 ALA B HB3    1 
ATOM   12980 N N      . SER B 1 369 ? -8.736  31.724  -41.383 1.00 16.32  ? 369 SER B N      1 
ATOM   12981 C CA     . SER B 1 369 ? -7.464  32.422  -41.517 1.00 16.09  ? 369 SER B CA     1 
ATOM   12982 C C      . SER B 1 369 ? -6.421  31.950  -40.502 1.00 17.87  ? 369 SER B C      1 
ATOM   12983 O O      . SER B 1 369 ? -5.243  31.792  -40.826 1.00 14.38  ? 369 SER B O      1 
ATOM   12984 C CB     . SER B 1 369 ? -7.655  33.929  -41.353 1.00 18.48  ? 369 SER B CB     1 
ATOM   12985 O OG     . SER B 1 369 ? -8.313  34.490  -42.473 1.00 19.85  ? 369 SER B OG     1 
ATOM   12986 H H      . SER B 1 369 ? -9.401  32.234  -41.192 1.00 19.58  ? 369 SER B H      1 
ATOM   12987 H HA     . SER B 1 369 ? -7.110  32.261  -42.405 1.00 19.30  ? 369 SER B HA     1 
ATOM   12988 H HB2    . SER B 1 369 ? -8.189  34.093  -40.560 1.00 22.17  ? 369 SER B HB2    1 
ATOM   12989 H HB3    . SER B 1 369 ? -6.785  34.347  -41.258 1.00 22.17  ? 369 SER B HB3    1 
ATOM   12990 H HG     . SER B 1 369 ? -8.409  35.317  -42.365 1.00 23.82  ? 369 SER B HG     1 
ATOM   12991 N N      . ILE B 1 370 ? -6.855  31.761  -39.262 1.00 16.82  ? 370 ILE B N      1 
ATOM   12992 C CA     . ILE B 1 370 ? -5.952  31.291  -38.223 1.00 16.18  ? 370 ILE B CA     1 
ATOM   12993 C C      . ILE B 1 370 ? -5.357  29.949  -38.624 1.00 16.09  ? 370 ILE B C      1 
ATOM   12994 O O      . ILE B 1 370 ? -4.149  29.746  -38.502 1.00 16.45  ? 370 ILE B O      1 
ATOM   12995 C CB     . ILE B 1 370 ? -6.670  31.191  -36.864 1.00 16.06  ? 370 ILE B CB     1 
ATOM   12996 C CG1    . ILE B 1 370 ? -6.978  32.601  -36.353 1.00 16.53  ? 370 ILE B CG1    1 
ATOM   12997 C CG2    . ILE B 1 370 ? -5.800  30.453  -35.834 1.00 14.23  ? 370 ILE B CG2    1 
ATOM   12998 C CD1    . ILE B 1 370 ? -7.947  32.632  -35.178 1.00 15.10  ? 370 ILE B CD1    1 
ATOM   12999 H H      . ILE B 1 370 ? -7.662  31.897  -38.998 1.00 20.18  ? 370 ILE B H      1 
ATOM   13000 H HA     . ILE B 1 370 ? -5.223  31.925  -38.129 1.00 19.42  ? 370 ILE B HA     1 
ATOM   13001 H HB     . ILE B 1 370 ? -7.503  30.707  -36.980 1.00 19.27  ? 370 ILE B HB     1 
ATOM   13002 H HG12   . ILE B 1 370 ? -6.150  33.015  -36.063 1.00 19.84  ? 370 ILE B HG12   1 
ATOM   13003 H HG13   . ILE B 1 370 ? -7.368  33.119  -37.074 1.00 19.84  ? 370 ILE B HG13   1 
ATOM   13004 H HG21   . ILE B 1 370 ? -6.159  30.605  -34.946 1.00 17.08  ? 370 ILE B HG21   1 
ATOM   13005 H HG22   . ILE B 1 370 ? -5.809  29.503  -36.031 1.00 17.08  ? 370 ILE B HG22   1 
ATOM   13006 H HG23   . ILE B 1 370 ? -4.894  30.795  -35.885 1.00 17.08  ? 370 ILE B HG23   1 
ATOM   13007 H HD11   . ILE B 1 370 ? -8.234  33.547  -35.031 1.00 18.12  ? 370 ILE B HD11   1 
ATOM   13008 H HD12   . ILE B 1 370 ? -8.713  32.075  -35.387 1.00 18.12  ? 370 ILE B HD12   1 
ATOM   13009 H HD13   . ILE B 1 370 ? -7.499  32.295  -34.387 1.00 18.12  ? 370 ILE B HD13   1 
ATOM   13010 N N      . TYR B 1 371 ? -6.180  29.038  -39.136 1.00 13.62  ? 371 TYR B N      1 
ATOM   13011 C CA     . TYR B 1 371 ? -5.650  27.746  -39.541 1.00 16.57  ? 371 TYR B CA     1 
ATOM   13012 C C      . TYR B 1 371 ? -4.664  27.902  -40.704 1.00 14.44  ? 371 TYR B C      1 
ATOM   13013 O O      . TYR B 1 371 ? -3.572  27.333  -40.687 1.00 17.10  ? 371 TYR B O      1 
ATOM   13014 C CB     . TYR B 1 371 ? -6.765  26.766  -39.930 1.00 17.27  ? 371 TYR B CB     1 
ATOM   13015 C CG     . TYR B 1 371 ? -6.185  25.524  -40.552 1.00 16.98  ? 371 TYR B CG     1 
ATOM   13016 C CD1    . TYR B 1 371 ? -5.610  24.533  -39.766 1.00 15.97  ? 371 TYR B CD1    1 
ATOM   13017 C CD2    . TYR B 1 371 ? -6.176  25.358  -41.932 1.00 16.98  ? 371 TYR B CD2    1 
ATOM   13018 C CE1    . TYR B 1 371 ? -5.047  23.410  -40.338 1.00 15.35  ? 371 TYR B CE1    1 
ATOM   13019 C CE2    . TYR B 1 371 ? -5.628  24.237  -42.513 1.00 17.21  ? 371 TYR B CE2    1 
ATOM   13020 C CZ     . TYR B 1 371 ? -5.064  23.269  -41.721 1.00 17.77  ? 371 TYR B CZ     1 
ATOM   13021 O OH     . TYR B 1 371 ? -4.506  22.169  -42.319 1.00 18.02  ? 371 TYR B OH     1 
ATOM   13022 H H      . TYR B 1 371 ? -7.025  29.140  -39.256 1.00 16.35  ? 371 TYR B H      1 
ATOM   13023 H HA     . TYR B 1 371 ? -5.163  27.361  -38.797 1.00 19.89  ? 371 TYR B HA     1 
ATOM   13024 H HB2    . TYR B 1 371 ? -7.261  26.509  -39.137 1.00 20.72  ? 371 TYR B HB2    1 
ATOM   13025 H HB3    . TYR B 1 371 ? -7.354  27.187  -40.576 1.00 20.72  ? 371 TYR B HB3    1 
ATOM   13026 H HD1    . TYR B 1 371 ? -5.596  24.632  -38.841 1.00 19.17  ? 371 TYR B HD1    1 
ATOM   13027 H HD2    . TYR B 1 371 ? -6.553  26.014  -42.473 1.00 20.37  ? 371 TYR B HD2    1 
ATOM   13028 H HE1    . TYR B 1 371 ? -4.666  22.751  -39.803 1.00 18.42  ? 371 TYR B HE1    1 
ATOM   13029 H HE2    . TYR B 1 371 ? -5.630  24.142  -43.438 1.00 20.65  ? 371 TYR B HE2    1 
ATOM   13030 H HH     . TYR B 1 371 ? -4.186  21.656  -41.736 1.00 21.62  ? 371 TYR B HH     1 
ATOM   13031 N N      . MET B 1 372 ? -5.019  28.693  -41.707 1.00 16.21  ? 372 MET B N      1 
ATOM   13032 C CA     . MET B 1 372 ? -4.140  28.808  -42.867 1.00 15.10  ? 372 MET B CA     1 
ATOM   13033 C C      . MET B 1 372 ? -2.794  29.432  -42.503 1.00 17.54  ? 372 MET B C      1 
ATOM   13034 O O      . MET B 1 372 ? -1.751  29.061  -43.056 1.00 19.03  ? 372 MET B O      1 
ATOM   13035 C CB     . MET B 1 372 ? -4.843  29.601  -43.973 1.00 16.28  ? 372 MET B CB     1 
ATOM   13036 C CG     . MET B 1 372 ? -5.966  28.784  -44.587 1.00 15.99  ? 372 MET B CG     1 
ATOM   13037 S SD     . MET B 1 372 ? -6.821  29.513  -46.006 1.00 20.07  ? 372 MET B SD     1 
ATOM   13038 C CE     . MET B 1 372 ? -7.687  30.851  -45.201 1.00 20.92  ? 372 MET B CE     1 
ATOM   13039 H H      . MET B 1 372 ? -5.739  29.161  -41.744 1.00 19.45  ? 372 MET B H      1 
ATOM   13040 H HA     . MET B 1 372 ? -3.976  27.917  -43.213 1.00 18.12  ? 372 MET B HA     1 
ATOM   13041 H HB2    . MET B 1 372 ? -5.222  30.411  -43.597 1.00 19.54  ? 372 MET B HB2    1 
ATOM   13042 H HB3    . MET B 1 372 ? -4.205  29.818  -44.670 1.00 19.54  ? 372 MET B HB3    1 
ATOM   13043 H HG2    . MET B 1 372 ? -5.598  27.936  -44.880 1.00 19.19  ? 372 MET B HG2    1 
ATOM   13044 H HG3    . MET B 1 372 ? -6.633  28.624  -43.902 1.00 19.19  ? 372 MET B HG3    1 
ATOM   13045 H HE1    . MET B 1 372 ? -8.019  31.460  -45.878 1.00 25.11  ? 372 MET B HE1    1 
ATOM   13046 H HE2    . MET B 1 372 ? -8.426  30.487  -44.689 1.00 25.11  ? 372 MET B HE2    1 
ATOM   13047 H HE3    . MET B 1 372 ? -7.072  31.317  -44.613 1.00 25.11  ? 372 MET B HE3    1 
ATOM   13048 N N      . GLU B 1 373 ? -2.821  30.335  -41.529 1.00 17.80  ? 373 GLU B N      1 
ATOM   13049 C CA     . GLU B 1 373 ? -1.632  31.040  -41.085 1.00 19.95  ? 373 GLU B CA     1 
ATOM   13050 C C      . GLU B 1 373 ? -0.704  30.172  -40.216 1.00 21.63  ? 373 GLU B C      1 
ATOM   13051 O O      . GLU B 1 373 ? 0.514   30.332  -40.270 1.00 21.27  ? 373 GLU B O      1 
ATOM   13052 C CB     . GLU B 1 373 ? -2.053  32.292  -40.312 1.00 23.89  ? 373 GLU B CB     1 
ATOM   13053 C CG     . GLU B 1 373 ? -0.904  33.134  -39.779 1.00 33.68  ? 373 GLU B CG     1 
ATOM   13054 C CD     . GLU B 1 373 ? -0.044  33.722  -40.884 1.00 58.70  ? 373 GLU B CD     1 
ATOM   13055 O OE1    . GLU B 1 373 ? -0.591  34.045  -41.961 1.00 41.76  ? 373 GLU B OE1    1 
ATOM   13056 O OE2    . GLU B 1 373 ? 1.180   33.857  -40.671 1.00 50.52  ? 373 GLU B OE2    1 
ATOM   13057 H H      . GLU B 1 373 ? -3.533  30.560  -41.103 1.00 21.36  ? 373 GLU B H      1 
ATOM   13058 H HA     . GLU B 1 373 ? -1.129  31.326  -41.863 1.00 23.95  ? 373 GLU B HA     1 
ATOM   13059 H HB2    . GLU B 1 373 ? -2.584  32.854  -40.898 1.00 28.67  ? 373 GLU B HB2    1 
ATOM   13060 H HB3    . GLU B 1 373 ? -2.590  32.018  -39.552 1.00 28.67  ? 373 GLU B HB3    1 
ATOM   13061 H HG2    . GLU B 1 373 ? -1.269  33.871  -39.265 1.00 40.42  ? 373 GLU B HG2    1 
ATOM   13062 H HG3    . GLU B 1 373 ? -0.337  32.588  -39.213 1.00 40.42  ? 373 GLU B HG3    1 
ATOM   13063 N N      . THR B 1 374 ? -1.272  29.256  -39.431 1.00 18.01  ? 374 THR B N      1 
ATOM   13064 C CA     . THR B 1 374 ? -0.513  28.576  -38.371 1.00 18.06  ? 374 THR B CA     1 
ATOM   13065 C C      . THR B 1 374 ? -0.637  27.055  -38.267 1.00 20.02  ? 374 THR B C      1 
ATOM   13066 O O      . THR B 1 374 ? 0.195   26.420  -37.623 1.00 17.48  ? 374 THR B O      1 
ATOM   13067 C CB     . THR B 1 374 ? -0.933  29.105  -36.995 1.00 20.20  ? 374 THR B CB     1 
ATOM   13068 O OG1    . THR B 1 374 ? -2.321  28.809  -36.776 1.00 17.83  ? 374 THR B OG1    1 
ATOM   13069 C CG2    . THR B 1 374 ? -0.705  30.601  -36.898 1.00 18.58  ? 374 THR B CG2    1 
ATOM   13070 H H      . THR B 1 374 ? -2.094  29.008  -39.489 1.00 21.62  ? 374 THR B H      1 
ATOM   13071 H HA     . THR B 1 374 ? 0.430   28.774  -38.478 1.00 21.67  ? 374 THR B HA     1 
ATOM   13072 H HB     . THR B 1 374 ? -0.402  28.672  -36.309 1.00 24.24  ? 374 THR B HB     1 
ATOM   13073 H HG1    . THR B 1 374 ? -2.790  29.177  -37.368 1.00 21.40  ? 374 THR B HG1    1 
ATOM   13074 H HG21   . THR B 1 374 ? -0.919  30.911  -36.004 1.00 22.30  ? 374 THR B HG21   1 
ATOM   13075 H HG22   . THR B 1 374 ? 0.223   30.808  -37.089 1.00 22.30  ? 374 THR B HG22   1 
ATOM   13076 H HG23   . THR B 1 374 ? -1.269  31.065  -37.536 1.00 22.30  ? 374 THR B HG23   1 
ATOM   13077 N N      . GLY B 1 375 ? -1.692  26.490  -38.839 1.00 15.11  ? 375 GLY B N      1 
ATOM   13078 C CA     . GLY B 1 375 ? -2.032  25.089  -38.615 1.00 15.05  ? 375 GLY B CA     1 
ATOM   13079 C C      . GLY B 1 375 ? -2.822  24.875  -37.330 1.00 17.38  ? 375 GLY B C      1 
ATOM   13080 O O      . GLY B 1 375 ? -3.002  23.735  -36.889 1.00 16.83  ? 375 GLY B O      1 
ATOM   13081 H H      . GLY B 1 375 ? -2.233  26.900  -39.367 1.00 18.13  ? 375 GLY B H      1 
ATOM   13082 H HA2    . GLY B 1 375 ? -2.566  24.766  -39.358 1.00 18.07  ? 375 GLY B HA2    1 
ATOM   13083 H HA3    . GLY B 1 375 ? -1.221  24.560  -38.569 1.00 18.07  ? 375 GLY B HA3    1 
ATOM   13084 N N      . VAL B 1 376 ? -3.300  25.970  -36.739 1.00 13.65  ? 376 VAL B N      1 
ATOM   13085 C CA     . VAL B 1 376 ? -4.087  25.926  -35.504 1.00 13.25  ? 376 VAL B CA     1 
ATOM   13086 C C      . VAL B 1 376 ? -5.580  25.859  -35.828 1.00 18.77  ? 376 VAL B C      1 
ATOM   13087 O O      . VAL B 1 376 ? -6.077  26.691  -36.585 1.00 16.90  ? 376 VAL B O      1 
ATOM   13088 C CB     . VAL B 1 376 ? -3.825  27.178  -34.623 1.00 16.98  ? 376 VAL B CB     1 
ATOM   13089 C CG1    . VAL B 1 376 ? -4.762  27.203  -33.419 1.00 17.94  ? 376 VAL B CG1    1 
ATOM   13090 C CG2    . VAL B 1 376 ? -2.356  27.255  -34.186 1.00 19.11  ? 376 VAL B CG2    1 
ATOM   13091 H H      . VAL B 1 376 ? -3.182  26.767  -37.038 1.00 16.38  ? 376 VAL B H      1 
ATOM   13092 H HA     . VAL B 1 376 ? -3.841  25.141  -34.997 1.00 15.90  ? 376 VAL B HA     1 
ATOM   13093 H HB     . VAL B 1 376 ? -4.016  27.969  -35.150 1.00 20.38  ? 376 VAL B HB     1 
ATOM   13094 H HG11   . VAL B 1 376 ? -4.422  27.838  -32.770 1.00 21.52  ? 376 VAL B HG11   1 
ATOM   13095 H HG12   . VAL B 1 376 ? -5.648  27.473  -33.708 1.00 21.52  ? 376 VAL B HG12   1 
ATOM   13096 H HG13   . VAL B 1 376 ? -4.795  26.317  -33.027 1.00 21.52  ? 376 VAL B HG13   1 
ATOM   13097 H HG21   . VAL B 1 376 ? -2.164  28.159  -33.892 1.00 22.93  ? 376 VAL B HG21   1 
ATOM   13098 H HG22   . VAL B 1 376 ? -2.210  26.634  -33.456 1.00 22.93  ? 376 VAL B HG22   1 
ATOM   13099 H HG23   . VAL B 1 376 ? -1.787  27.026  -34.937 1.00 22.93  ? 376 VAL B HG23   1 
ATOM   13100 N N      . ARG B 1 377 ? -6.298  24.896  -35.249 1.00 13.46  ? 377 ARG B N      1 
ATOM   13101 C CA     . ARG B 1 377 ? -7.748  24.849  -35.411 1.00 14.46  ? 377 ARG B CA     1 
ATOM   13102 C C      . ARG B 1 377 ? -8.467  25.449  -34.211 1.00 15.09  ? 377 ARG B C      1 
ATOM   13103 O O      . ARG B 1 377 ? -8.189  25.088  -33.061 1.00 16.96  ? 377 ARG B O      1 
ATOM   13104 C CB     . ARG B 1 377 ? -8.242  23.410  -35.635 1.00 13.57  ? 377 ARG B CB     1 
ATOM   13105 C CG     . ARG B 1 377 ? -9.767  23.299  -35.560 1.00 16.60  ? 377 ARG B CG     1 
ATOM   13106 C CD     . ARG B 1 377 ? -10.335 22.094  -36.301 1.00 17.42  ? 377 ARG B CD     1 
ATOM   13107 N NE     . ARG B 1 377 ? -10.007 20.816  -35.679 1.00 14.73  ? 377 ARG B NE     1 
ATOM   13108 C CZ     . ARG B 1 377 ? -10.425 19.643  -36.147 1.00 19.63  ? 377 ARG B CZ     1 
ATOM   13109 N NH1    . ARG B 1 377 ? -11.194 19.594  -37.228 1.00 18.75  ? 377 ARG B NH1    1 
ATOM   13110 N NH2    . ARG B 1 377 ? -10.073 18.518  -35.544 1.00 17.36  ? 377 ARG B NH2    1 
ATOM   13111 H H      . ARG B 1 377 ? -5.973  24.266  -34.763 1.00 16.15  ? 377 ARG B H      1 
ATOM   13112 H HA     . ARG B 1 377 ? -8.005  25.362  -36.192 1.00 17.35  ? 377 ARG B HA     1 
ATOM   13113 H HB2    . ARG B 1 377 ? -7.961  23.111  -36.514 1.00 16.28  ? 377 ARG B HB2    1 
ATOM   13114 H HB3    . ARG B 1 377 ? -7.864  22.835  -34.951 1.00 16.28  ? 377 ARG B HB3    1 
ATOM   13115 H HG2    . ARG B 1 377 ? -10.030 23.223  -34.629 1.00 19.92  ? 377 ARG B HG2    1 
ATOM   13116 H HG3    . ARG B 1 377 ? -10.158 24.097  -35.948 1.00 19.92  ? 377 ARG B HG3    1 
ATOM   13117 H HD2    . ARG B 1 377 ? -11.301 22.171  -36.327 1.00 20.91  ? 377 ARG B HD2    1 
ATOM   13118 H HD3    . ARG B 1 377 ? -9.981  22.085  -37.204 1.00 20.91  ? 377 ARG B HD3    1 
ATOM   13119 H HE     . ARG B 1 377 ? -9.630  20.830  -34.906 1.00 17.68  ? 377 ARG B HE     1 
ATOM   13120 H HH11   . ARG B 1 377 ? -11.424 20.318  -37.631 1.00 22.50  ? 377 ARG B HH11   1 
ATOM   13121 H HH12   . ARG B 1 377 ? -11.464 18.834  -37.527 1.00 22.50  ? 377 ARG B HH12   1 
ATOM   13122 H HH21   . ARG B 1 377 ? -9.578  18.544  -34.841 1.00 20.83  ? 377 ARG B HH21   1 
ATOM   13123 H HH22   . ARG B 1 377 ? -10.352 17.763  -35.846 1.00 20.83  ? 377 ARG B HH22   1 
ATOM   13124 N N      . SER B 1 378 ? -9.386  26.369  -34.502 1.00 15.90  ? 378 SER B N      1 
ATOM   13125 C CA     . SER B 1 378 ? -10.276 26.972  -33.514 1.00 15.76  ? 378 SER B CA     1 
ATOM   13126 C C      . SER B 1 378 ? -11.733 26.739  -33.906 1.00 19.30  ? 378 SER B C      1 
ATOM   13127 O O      . SER B 1 378 ? -12.020 26.346  -35.046 1.00 17.22  ? 378 SER B O      1 
ATOM   13128 C CB     . SER B 1 378 ? -9.999  28.467  -33.400 1.00 18.19  ? 378 SER B CB     1 
ATOM   13129 O OG     . SER B 1 378 ? -10.103 29.093  -34.675 1.00 19.07  ? 378 SER B OG     1 
ATOM   13130 H H      . SER B 1 378 ? -9.516  26.670  -35.297 1.00 19.07  ? 378 SER B H      1 
ATOM   13131 H HA     . SER B 1 378 ? -10.127 26.567  -32.646 1.00 18.92  ? 378 SER B HA     1 
ATOM   13132 H HB2    . SER B 1 378 ? -10.646 28.865  -32.797 1.00 21.83  ? 378 SER B HB2    1 
ATOM   13133 H HB3    . SER B 1 378 ? -9.101  28.596  -33.057 1.00 21.83  ? 378 SER B HB3    1 
ATOM   13134 H HG     . SER B 1 378 ? -9.538  28.765  -35.203 1.00 22.88  ? 378 SER B HG     1 
ATOM   13135 N N      . MET B 1 379 ? -12.654 26.990  -32.977 1.00 18.80  ? 379 MET B N      1 
ATOM   13136 C CA     . MET B 1 379 ? -14.072 26.734  -33.227 1.00 16.59  ? 379 MET B CA     1 
ATOM   13137 C C      . MET B 1 379 ? -14.876 28.010  -33.434 1.00 18.78  ? 379 MET B C      1 
ATOM   13138 O O      . MET B 1 379 ? -14.821 28.935  -32.620 1.00 17.09  ? 379 MET B O      1 
ATOM   13139 C CB     . MET B 1 379 ? -14.721 25.954  -32.074 1.00 18.86  ? 379 MET B CB     1 
ATOM   13140 C CG     . MET B 1 379 ? -16.108 25.395  -32.456 1.00 23.75  ? 379 MET B CG     1 
ATOM   13141 S SD     . MET B 1 379 ? -17.034 24.522  -31.157 1.00 24.63  ? 379 MET B SD     1 
ATOM   13142 C CE     . MET B 1 379 ? -16.139 22.952  -31.137 1.00 21.82  ? 379 MET B CE     1 
ATOM   13143 H H      . MET B 1 379 ? -12.485 27.308  -32.196 1.00 22.56  ? 379 MET B H      1 
ATOM   13144 H HA     . MET B 1 379 ? -14.162 26.187  -34.022 1.00 19.90  ? 379 MET B HA     1 
ATOM   13145 H HB2    . MET B 1 379 ? -14.151 25.211  -31.825 1.00 22.63  ? 379 MET B HB2    1 
ATOM   13146 H HB3    . MET B 1 379 ? -14.837 26.550  -31.317 1.00 22.63  ? 379 MET B HB3    1 
ATOM   13147 H HG2    . MET B 1 379 ? -16.663 26.133  -32.751 1.00 28.50  ? 379 MET B HG2    1 
ATOM   13148 H HG3    . MET B 1 379 ? -15.990 24.772  -33.190 1.00 28.50  ? 379 MET B HG3    1 
ATOM   13149 H HE1    . MET B 1 379 ? -16.459 22.415  -30.396 1.00 26.19  ? 379 MET B HE1    1 
ATOM   13150 H HE2    . MET B 1 379 ? -16.294 22.489  -31.974 1.00 26.19  ? 379 MET B HE2    1 
ATOM   13151 H HE3    . MET B 1 379 ? -15.195 23.134  -31.031 1.00 26.19  ? 379 MET B HE3    1 
ATOM   13152 N N      . GLU B 1 380 ? -15.637 28.045  -34.522 1.00 20.54  ? 380 GLU B N      1 
ATOM   13153 C CA     . GLU B 1 380 ? -16.631 29.096  -34.710 1.00 22.76  ? 380 GLU B CA     1 
ATOM   13154 C C      . GLU B 1 380 ? -17.736 28.930  -33.684 1.00 19.88  ? 380 GLU B C      1 
ATOM   13155 O O      . GLU B 1 380 ? -18.354 27.864  -33.594 1.00 21.62  ? 380 GLU B O      1 
ATOM   13156 C CB     . GLU B 1 380 ? -17.230 29.052  -36.115 1.00 23.35  ? 380 GLU B CB     1 
ATOM   13157 C CG     . GLU B 1 380 ? -17.947 30.347  -36.536 1.00 20.86  ? 380 GLU B CG     1 
ATOM   13158 C CD     . GLU B 1 380 ? -19.454 30.382  -36.246 1.00 27.34  ? 380 GLU B CD     1 
ATOM   13159 O OE1    . GLU B 1 380 ? -20.013 29.445  -35.627 1.00 23.78  ? 380 GLU B OE1    1 
ATOM   13160 O OE2    . GLU B 1 380 ? -20.092 31.387  -36.648 1.00 24.34  ? 380 GLU B OE2    1 
ATOM   13161 H H      . GLU B 1 380 ? -15.598 27.474  -35.164 1.00 24.65  ? 380 GLU B H      1 
ATOM   13162 H HA     . GLU B 1 380 ? -16.215 29.962  -34.579 1.00 27.31  ? 380 GLU B HA     1 
ATOM   13163 H HB2    . GLU B 1 380 ? -16.514 28.895  -36.750 1.00 28.02  ? 380 GLU B HB2    1 
ATOM   13164 H HB3    . GLU B 1 380 ? -17.869 28.324  -36.161 1.00 28.02  ? 380 GLU B HB3    1 
ATOM   13165 H HG2    . GLU B 1 380 ? -17.542 31.092  -36.065 1.00 25.03  ? 380 GLU B HG2    1 
ATOM   13166 H HG3    . GLU B 1 380 ? -17.831 30.466  -37.492 1.00 25.03  ? 380 GLU B HG3    1 
ATOM   13167 N N      . ARG B 1 381 ? -17.969 29.982  -32.908 1.00 22.97  ? 381 ARG B N      1 
ATOM   13168 C CA     . ARG B 1 381 ? -19.126 30.045  -32.019 1.00 25.10  ? 381 ARG B CA     1 
ATOM   13169 C C      . ARG B 1 381 ? -19.826 31.382  -32.253 1.00 26.35  ? 381 ARG B C      1 
ATOM   13170 O O      . ARG B 1 381 ? -19.695 32.325  -31.467 1.00 25.17  ? 381 ARG B O      1 
ATOM   13171 C CB     . ARG B 1 381 ? -18.707 29.877  -30.556 1.00 24.34  ? 381 ARG B CB     1 
ATOM   13172 C CG     . ARG B 1 381 ? -18.120 28.490  -30.230 1.00 23.47  ? 381 ARG B CG     1 
ATOM   13173 C CD     . ARG B 1 381 ? -19.195 27.406  -30.045 1.00 23.58  ? 381 ARG B CD     1 
ATOM   13174 N NE     . ARG B 1 381 ? -19.589 26.765  -31.298 1.00 23.90  ? 381 ARG B NE     1 
ATOM   13175 C CZ     . ARG B 1 381 ? -20.312 25.647  -31.381 1.00 28.27  ? 381 ARG B CZ     1 
ATOM   13176 N NH1    . ARG B 1 381 ? -20.718 25.024  -30.282 1.00 28.89  ? 381 ARG B NH1    1 
ATOM   13177 N NH2    . ARG B 1 381 ? -20.624 25.141  -32.566 1.00 26.98  ? 381 ARG B NH2    1 
ATOM   13178 H H      . ARG B 1 381 ? -17.467 30.680  -32.877 1.00 27.56  ? 381 ARG B H      1 
ATOM   13179 H HA     . ARG B 1 381 ? -19.751 29.337  -32.239 1.00 30.13  ? 381 ARG B HA     1 
ATOM   13180 H HB2    . ARG B 1 381 ? -18.030 30.540  -30.348 1.00 29.21  ? 381 ARG B HB2    1 
ATOM   13181 H HB3    . ARG B 1 381 ? -19.484 30.012  -29.991 1.00 29.21  ? 381 ARG B HB3    1 
ATOM   13182 H HG2    . ARG B 1 381 ? -17.540 28.214  -30.957 1.00 28.17  ? 381 ARG B HG2    1 
ATOM   13183 H HG3    . ARG B 1 381 ? -17.612 28.550  -29.406 1.00 28.17  ? 381 ARG B HG3    1 
ATOM   13184 H HD2    . ARG B 1 381 ? -18.848 26.719  -29.455 1.00 28.29  ? 381 ARG B HD2    1 
ATOM   13185 H HD3    . ARG B 1 381 ? -19.986 27.809  -29.654 1.00 28.29  ? 381 ARG B HD3    1 
ATOM   13186 H HE     . ARG B 1 381 ? -19.337 27.134  -32.033 1.00 28.69  ? 381 ARG B HE     1 
ATOM   13187 H HH11   . ARG B 1 381 ? -20.523 25.341  -29.507 1.00 34.67  ? 381 ARG B HH11   1 
ATOM   13188 H HH12   . ARG B 1 381 ? -21.182 24.303  -30.345 1.00 34.67  ? 381 ARG B HH12   1 
ATOM   13189 H HH21   . ARG B 1 381 ? -20.363 25.536  -33.284 1.00 32.38  ? 381 ARG B HH21   1 
ATOM   13190 H HH22   . ARG B 1 381 ? -21.087 24.418  -32.616 1.00 32.38  ? 381 ARG B HH22   1 
ATOM   13191 N N      . GLY B 1 382 ? -20.549 31.450  -33.368 1.00 23.09  ? 382 GLY B N      1 
ATOM   13192 C CA     . GLY B 1 382 ? -21.199 32.673  -33.797 1.00 24.14  ? 382 GLY B CA     1 
ATOM   13193 C C      . GLY B 1 382 ? -22.419 32.371  -34.642 1.00 23.97  ? 382 GLY B C      1 
ATOM   13194 O O      . GLY B 1 382 ? -23.140 31.399  -34.396 1.00 22.84  ? 382 GLY B O      1 
ATOM   13195 H H      . GLY B 1 382 ? -20.677 30.786  -33.899 1.00 27.71  ? 382 GLY B H      1 
ATOM   13196 H HA2    . GLY B 1 382 ? -21.478 33.188  -33.024 1.00 28.96  ? 382 GLY B HA2    1 
ATOM   13197 H HA3    . GLY B 1 382 ? -20.581 33.206  -34.321 1.00 28.96  ? 382 GLY B HA3    1 
ATOM   13198 N N      . ILE B 1 383 ? -22.635 33.200  -35.658 1.00 23.77  ? 383 ILE B N      1 
ATOM   13199 C CA     . ILE B 1 383 ? -23.848 33.133  -36.454 1.00 22.44  ? 383 ILE B CA     1 
ATOM   13200 C C      . ILE B 1 383 ? -24.023 31.775  -37.158 1.00 25.57  ? 383 ILE B C      1 
ATOM   13201 O O      . ILE B 1 383 ? -25.143 31.289  -37.294 1.00 26.25  ? 383 ILE B O      1 
ATOM   13202 C CB     . ILE B 1 383 ? -23.884 34.306  -37.490 1.00 24.54  ? 383 ILE B CB     1 
ATOM   13203 C CG1    . ILE B 1 383 ? -25.140 34.219  -38.354 1.00 28.97  ? 383 ILE B CG1    1 
ATOM   13204 C CG2    . ILE B 1 383 ? -22.617 34.345  -38.355 1.00 24.27  ? 383 ILE B CG2    1 
ATOM   13205 C CD1    . ILE B 1 383 ? -25.423 35.505  -39.139 1.00 36.01  ? 383 ILE B CD1    1 
ATOM   13206 H H      . ILE B 1 383 ? -22.088 33.816  -35.902 1.00 28.52  ? 383 ILE B H      1 
ATOM   13207 H HA     . ILE B 1 383 ? -24.607 33.249  -35.861 1.00 26.92  ? 383 ILE B HA     1 
ATOM   13208 H HB     . ILE B 1 383 ? -23.926 35.137  -36.992 1.00 29.45  ? 383 ILE B HB     1 
ATOM   13209 H HG12   . ILE B 1 383 ? -25.032 33.500  -38.996 1.00 34.76  ? 383 ILE B HG12   1 
ATOM   13210 H HG13   . ILE B 1 383 ? -25.901 34.040  -37.784 1.00 34.76  ? 383 ILE B HG13   1 
ATOM   13211 H HG21   . ILE B 1 383 ? -22.714 35.035  -39.029 1.00 29.13  ? 383 ILE B HG21   1 
ATOM   13212 H HG22   . ILE B 1 383 ? -21.852 34.542  -37.792 1.00 29.13  ? 383 ILE B HG22   1 
ATOM   13213 H HG23   . ILE B 1 383 ? -22.500 33.482  -38.782 1.00 29.13  ? 383 ILE B HG23   1 
ATOM   13214 H HD11   . ILE B 1 383 ? -26.294 35.433  -39.559 1.00 43.21  ? 383 ILE B HD11   1 
ATOM   13215 H HD12   . ILE B 1 383 ? -25.412 36.257  -38.526 1.00 43.21  ? 383 ILE B HD12   1 
ATOM   13216 H HD13   . ILE B 1 383 ? -24.738 35.621  -39.816 1.00 43.21  ? 383 ILE B HD13   1 
ATOM   13217 N N      . ILE B 1 384 ? -22.936 31.136  -37.570 1.00 22.90  ? 384 ILE B N      1 
ATOM   13218 C CA     . ILE B 1 384 ? -23.075 29.844  -38.240 1.00 22.35  ? 384 ILE B CA     1 
ATOM   13219 C C      . ILE B 1 384 ? -23.564 28.782  -37.254 1.00 23.49  ? 384 ILE B C      1 
ATOM   13220 O O      . ILE B 1 384 ? -24.526 28.052  -37.535 1.00 23.69  ? 384 ILE B O      1 
ATOM   13221 C CB     . ILE B 1 384 ? -21.754 29.397  -38.888 1.00 23.21  ? 384 ILE B CB     1 
ATOM   13222 C CG1    . ILE B 1 384 ? -21.270 30.464  -39.875 1.00 23.07  ? 384 ILE B CG1    1 
ATOM   13223 C CG2    . ILE B 1 384 ? -21.923 28.032  -39.581 1.00 23.25  ? 384 ILE B CG2    1 
ATOM   13224 C CD1    . ILE B 1 384 ? -22.251 30.770  -41.001 1.00 27.10  ? 384 ILE B CD1    1 
ATOM   13225 H H      . ILE B 1 384 ? -22.128 31.416  -37.479 1.00 27.49  ? 384 ILE B H      1 
ATOM   13226 H HA     . ILE B 1 384 ? -23.741 29.922  -38.940 1.00 26.82  ? 384 ILE B HA     1 
ATOM   13227 H HB     . ILE B 1 384 ? -21.088 29.303  -38.189 1.00 27.85  ? 384 ILE B HB     1 
ATOM   13228 H HG12   . ILE B 1 384 ? -21.109 31.289  -39.391 1.00 27.69  ? 384 ILE B HG12   1 
ATOM   13229 H HG13   . ILE B 1 384 ? -20.444 30.158  -40.281 1.00 27.69  ? 384 ILE B HG13   1 
ATOM   13230 H HG21   . ILE B 1 384 ? -21.166 27.883  -40.169 1.00 27.90  ? 384 ILE B HG21   1 
ATOM   13231 H HG22   . ILE B 1 384 ? -21.959 27.336  -38.907 1.00 27.90  ? 384 ILE B HG22   1 
ATOM   13232 H HG23   . ILE B 1 384 ? -22.745 28.039  -40.096 1.00 27.90  ? 384 ILE B HG23   1 
ATOM   13233 H HD11   . ILE B 1 384 ? -21.806 31.319  -41.665 1.00 32.52  ? 384 ILE B HD11   1 
ATOM   13234 H HD12   . ILE B 1 384 ? -22.543 29.938  -41.404 1.00 32.52  ? 384 ILE B HD12   1 
ATOM   13235 H HD13   . ILE B 1 384 ? -23.014 31.246  -40.637 1.00 32.52  ? 384 ILE B HD13   1 
ATOM   13236 N N      . SER B 1 385 ? -22.914 28.694  -36.096 1.00 22.37  ? 385 SER B N      1 
ATOM   13237 C CA     . SER B 1 385 ? -23.309 27.717  -35.083 1.00 24.60  ? 385 SER B CA     1 
ATOM   13238 C C      . SER B 1 385 ? -24.715 27.977  -34.563 1.00 30.40  ? 385 SER B C      1 
ATOM   13239 O O      . SER B 1 385 ? -25.411 27.043  -34.168 1.00 24.99  ? 385 SER B O      1 
ATOM   13240 C CB     . SER B 1 385 ? -22.322 27.725  -33.913 1.00 23.95  ? 385 SER B CB     1 
ATOM   13241 O OG     . SER B 1 385 ? -21.063 27.202  -34.311 1.00 26.69  ? 385 SER B OG     1 
ATOM   13242 H H      . SER B 1 385 ? -22.244 29.185  -35.873 1.00 26.84  ? 385 SER B H      1 
ATOM   13243 H HA     . SER B 1 385 ? -23.299 26.832  -35.476 1.00 29.52  ? 385 SER B HA     1 
ATOM   13244 H HB2    . SER B 1 385 ? -22.202 28.638  -33.607 1.00 28.74  ? 385 SER B HB2    1 
ATOM   13245 H HB3    . SER B 1 385 ? -22.678 27.178  -33.195 1.00 28.74  ? 385 SER B HB3    1 
ATOM   13246 H HG     . SER B 1 385 ? -20.743 27.666  -34.933 1.00 32.03  ? 385 SER B HG     1 
ATOM   13247 N N      . ALA B 1 386 ? -25.126 29.244  -34.556 1.00 25.84  ? 386 ALA B N      1 
ATOM   13248 C CA     . ALA B 1 386 ? -26.446 29.626  -34.055 1.00 26.86  ? 386 ALA B CA     1 
ATOM   13249 C C      . ALA B 1 386 ? -27.572 29.057  -34.915 1.00 27.26  ? 386 ALA B C      1 
ATOM   13250 O O      . ALA B 1 386 ? -28.699 28.888  -34.445 1.00 31.76  ? 386 ALA B O      1 
ATOM   13251 C CB     . ALA B 1 386 ? -26.555 31.129  -33.982 1.00 29.41  ? 386 ALA B CB     1 
ATOM   13252 H H      . ALA B 1 386 ? -24.656 29.907  -34.838 1.00 31.00  ? 386 ALA B H      1 
ATOM   13253 H HA     . ALA B 1 386 ? -26.553 29.276  -33.157 1.00 32.24  ? 386 ALA B HA     1 
ATOM   13254 H HB1    . ALA B 1 386 ? -27.442 31.366  -33.668 1.00 35.29  ? 386 ALA B HB1    1 
ATOM   13255 H HB2    . ALA B 1 386 ? -25.886 31.461  -33.365 1.00 35.29  ? 386 ALA B HB2    1 
ATOM   13256 H HB3    . ALA B 1 386 ? -26.406 31.500  -34.866 1.00 35.29  ? 386 ALA B HB3    1 
ATOM   13257 N N      . GLY B 1 387 ? -27.267 28.775  -36.177 1.00 26.62  ? 387 GLY B N      1 
ATOM   13258 C CA     . GLY B 1 387 ? -28.215 28.129  -37.070 1.00 31.89  ? 387 GLY B CA     1 
ATOM   13259 C C      . GLY B 1 387 ? -29.281 29.079  -37.582 1.00 34.62  ? 387 GLY B C      1 
ATOM   13260 O O      . GLY B 1 387 ? -29.242 30.277  -37.307 1.00 29.73  ? 387 GLY B O      1 
ATOM   13261 H H      . GLY B 1 387 ? -26.509 28.951  -36.543 1.00 31.94  ? 387 GLY B H      1 
ATOM   13262 H HA2    . GLY B 1 387 ? -27.741 27.761  -37.832 1.00 38.27  ? 387 GLY B HA2    1 
ATOM   13263 H HA3    . GLY B 1 387 ? -28.653 27.401  -36.602 1.00 38.27  ? 387 GLY B HA3    1 
ATOM   13264 N N      . ARG B 1 388 ? -30.239 28.541  -38.328 1.00 33.74  ? 388 ARG B N      1 
ATOM   13265 C CA     . ARG B 1 388 ? -31.320 29.356  -38.871 1.00 39.94  ? 388 ARG B CA     1 
ATOM   13266 C C      . ARG B 1 388 ? -32.564 29.351  -38.002 1.00 43.02  ? 388 ARG B C      1 
ATOM   13267 O O      . ARG B 1 388 ? -32.859 28.381  -37.299 1.00 41.76  ? 388 ARG B O      1 
ATOM   13268 C CB     . ARG B 1 388 ? -31.687 28.892  -40.274 1.00 37.91  ? 388 ARG B CB     1 
ATOM   13269 C CG     . ARG B 1 388 ? -30.824 29.530  -41.320 1.00 41.06  ? 388 ARG B CG     1 
ATOM   13270 C CD     . ARG B 1 388 ? -31.366 29.352  -42.699 1.00 35.14  ? 388 ARG B CD     1 
ATOM   13271 N NE     . ARG B 1 388 ? -30.306 29.573  -43.677 1.00 35.24  ? 388 ARG B NE     1 
ATOM   13272 C CZ     . ARG B 1 388 ? -30.020 30.740  -44.242 1.00 40.38  ? 388 ARG B CZ     1 
ATOM   13273 N NH1    . ARG B 1 388 ? -30.722 31.832  -43.948 1.00 39.28  ? 388 ARG B NH1    1 
ATOM   13274 N NH2    . ARG B 1 388 ? -29.024 30.810  -45.114 1.00 39.48  ? 388 ARG B NH2    1 
ATOM   13275 H H      . ARG B 1 388 ? -30.287 27.708  -38.535 1.00 40.48  ? 388 ARG B H      1 
ATOM   13276 H HA     . ARG B 1 388 ? -31.020 30.275  -38.941 1.00 47.93  ? 388 ARG B HA     1 
ATOM   13277 H HB2    . ARG B 1 388 ? -31.572 27.931  -40.332 1.00 45.49  ? 388 ARG B HB2    1 
ATOM   13278 H HB3    . ARG B 1 388 ? -32.609 29.130  -40.457 1.00 45.49  ? 388 ARG B HB3    1 
ATOM   13279 H HG2    . ARG B 1 388 ? -30.755 30.481  -41.144 1.00 49.28  ? 388 ARG B HG2    1 
ATOM   13280 H HG3    . ARG B 1 388 ? -29.947 29.120  -41.291 1.00 49.28  ? 388 ARG B HG3    1 
ATOM   13281 H HD2    . ARG B 1 388 ? -31.691 28.444  -42.801 1.00 42.17  ? 388 ARG B HD2    1 
ATOM   13282 H HD3    . ARG B 1 388 ? -32.082 29.984  -42.855 1.00 42.17  ? 388 ARG B HD3    1 
ATOM   13283 H HE     . ARG B 1 388 ? -29.867 28.885  -43.946 1.00 42.29  ? 388 ARG B HE     1 
ATOM   13284 H HH11   . ARG B 1 388 ? -31.368 31.795  -43.382 1.00 47.13  ? 388 ARG B HH11   1 
ATOM   13285 H HH12   . ARG B 1 388 ? -30.525 32.580  -44.324 1.00 47.13  ? 388 ARG B HH12   1 
ATOM   13286 H HH21   . ARG B 1 388 ? -28.571 30.105  -45.307 1.00 47.37  ? 388 ARG B HH21   1 
ATOM   13287 H HH22   . ARG B 1 388 ? -28.833 31.560  -45.489 1.00 47.37  ? 388 ARG B HH22   1 
ATOM   13288 N N      . ASN B 1 389 ? -33.277 30.469  -38.059 1.00 46.38  ? 389 ASN B N      1 
ATOM   13289 C CA     . ASN B 1 389 ? -34.590 30.594  -37.454 1.00 50.15  ? 389 ASN B CA     1 
ATOM   13290 C C      . ASN B 1 389 ? -35.587 29.811  -38.301 1.00 54.91  ? 389 ASN B C      1 
ATOM   13291 O O      . ASN B 1 389 ? -35.722 30.049  -39.505 1.00 49.85  ? 389 ASN B O      1 
ATOM   13292 C CB     . ASN B 1 389 ? -34.981 32.069  -37.342 1.00 50.15  ? 389 ASN B CB     1 
ATOM   13293 C CG     . ASN B 1 389 ? -36.299 32.278  -36.622 1.00 54.68  ? 389 ASN B CG     1 
ATOM   13294 O OD1    . ASN B 1 389 ? -37.284 31.586  -36.883 1.00 50.59  ? 389 ASN B OD1    1 
ATOM   13295 N ND2    . ASN B 1 389 ? -36.321 33.243  -35.709 1.00 61.39  ? 389 ASN B ND2    1 
ATOM   13296 H H      . ASN B 1 389 ? -33.012 31.186  -38.453 1.00 55.65  ? 389 ASN B H      1 
ATOM   13297 H HA     . ASN B 1 389 ? -34.575 30.211  -36.563 1.00 60.18  ? 389 ASN B HA     1 
ATOM   13298 H HB2    . ASN B 1 389 ? -34.292 32.540  -36.848 1.00 60.18  ? 389 ASN B HB2    1 
ATOM   13299 H HB3    . ASN B 1 389 ? -35.060 32.439  -38.234 1.00 60.18  ? 389 ASN B HB3    1 
ATOM   13300 H HD21   . ASN B 1 389 ? -37.043 33.403  -35.270 1.00 73.67  ? 389 ASN B HD21   1 
ATOM   13301 H HD22   . ASN B 1 389 ? -35.613 33.708  -35.557 1.00 73.67  ? 389 ASN B HD22   1 
ATOM   13302 N N      . LYS B 1 390 ? -36.278 28.871  -37.668 1.00 55.15  ? 390 LYS B N      1 
ATOM   13303 C CA     . LYS B 1 390 ? -37.132 27.938  -38.391 1.00 66.27  ? 390 LYS B CA     1 
ATOM   13304 C C      . LYS B 1 390 ? -38.336 28.612  -39.044 1.00 70.88  ? 390 LYS B C      1 
ATOM   13305 O O      . LYS B 1 390 ? -38.732 28.247  -40.154 1.00 64.33  ? 390 LYS B O      1 
ATOM   13306 C CB     . LYS B 1 390 ? -37.612 26.840  -37.448 1.00 69.56  ? 390 LYS B CB     1 
ATOM   13307 C CG     . LYS B 1 390 ? -38.415 27.356  -36.256 1.00 91.00  ? 390 LYS B CG     1 
ATOM   13308 C CD     . LYS B 1 390 ? -38.952 26.223  -35.399 1.00 100.00 ? 390 LYS B CD     1 
ATOM   13309 C CE     . LYS B 1 390 ? -39.956 25.361  -36.160 1.00 86.94  ? 390 LYS B CE     1 
ATOM   13310 N NZ     . LYS B 1 390 ? -40.399 24.188  -35.369 1.00 73.45  ? 390 LYS B NZ     1 
ATOM   13311 H H      . LYS B 1 390 ? -36.268 28.752  -36.817 1.00 66.17  ? 390 LYS B H      1 
ATOM   13312 H HA     . LYS B 1 390 ? -36.611 27.519  -39.093 1.00 79.52  ? 390 LYS B HA     1 
ATOM   13313 H HB2    . LYS B 1 390 ? -38.170 26.235  -37.957 1.00 83.47  ? 390 LYS B HB2    1 
ATOM   13314 H HB3    . LYS B 1 390 ? -36.840 26.365  -37.103 1.00 83.47  ? 390 LYS B HB3    1 
ATOM   13315 H HG2    . LYS B 1 390 ? -37.845 27.911  -35.701 1.00 109.20 ? 390 LYS B HG2    1 
ATOM   13316 H HG3    . LYS B 1 390 ? -39.174 27.868  -36.574 1.00 109.20 ? 390 LYS B HG3    1 
ATOM   13317 H HD2    . LYS B 1 390 ? -38.215 25.656  -35.122 1.00 120.00 ? 390 LYS B HD2    1 
ATOM   13318 H HD3    . LYS B 1 390 ? -39.399 26.595  -34.623 1.00 120.00 ? 390 LYS B HD3    1 
ATOM   13319 H HE2    . LYS B 1 390 ? -40.737 25.895  -36.372 1.00 104.33 ? 390 LYS B HE2    1 
ATOM   13320 H HE3    . LYS B 1 390 ? -39.552 25.023  -36.972 1.00 104.33 ? 390 LYS B HE3    1 
ATOM   13321 H HZ1    . LYS B 1 390 ? -40.982 23.707  -35.839 1.00 88.14  ? 390 LYS B HZ1    1 
ATOM   13322 H HZ2    . LYS B 1 390 ? -39.699 23.677  -35.166 1.00 88.14  ? 390 LYS B HZ2    1 
ATOM   13323 H HZ3    . LYS B 1 390 ? -40.788 24.459  -34.616 1.00 88.14  ? 390 LYS B HZ3    1 
ATOM   13324 N N      . GLU B 1 391 ? -38.915 29.590  -38.353 1.00 73.37  ? 391 GLU B N      1 
ATOM   13325 C CA     . GLU B 1 391 ? -40.072 30.310  -38.872 1.00 71.38  ? 391 GLU B CA     1 
ATOM   13326 C C      . GLU B 1 391 ? -39.677 31.239  -40.015 1.00 69.51  ? 391 GLU B C      1 
ATOM   13327 O O      . GLU B 1 391 ? -40.079 31.036  -41.164 1.00 68.93  ? 391 GLU B O      1 
ATOM   13328 C CB     . GLU B 1 391 ? -40.747 31.116  -37.759 1.00 72.20  ? 391 GLU B CB     1 
ATOM   13329 C CG     . GLU B 1 391 ? -41.687 30.299  -36.890 1.00 81.24  ? 391 GLU B CG     1 
ATOM   13330 C CD     . GLU B 1 391 ? -42.575 31.169  -36.021 1.00 101.18 ? 391 GLU B CD     1 
ATOM   13331 O OE1    . GLU B 1 391 ? -42.039 32.040  -35.304 1.00 102.75 ? 391 GLU B OE1    1 
ATOM   13332 O OE2    . GLU B 1 391 ? -43.810 30.986  -36.065 1.00 103.22 ? 391 GLU B OE2    1 
ATOM   13333 H H      . GLU B 1 391 ? -38.655 29.856  -37.578 1.00 88.05  ? 391 GLU B H      1 
ATOM   13334 H HA     . GLU B 1 391 ? -40.716 29.670  -39.213 1.00 85.65  ? 391 GLU B HA     1 
ATOM   13335 H HB2    . GLU B 1 391 ? -40.061 31.489  -37.184 1.00 86.64  ? 391 GLU B HB2    1 
ATOM   13336 H HB3    . GLU B 1 391 ? -41.263 31.832  -38.161 1.00 86.64  ? 391 GLU B HB3    1 
ATOM   13337 H HG2    . GLU B 1 391 ? -42.258 29.761  -37.460 1.00 97.48  ? 391 GLU B HG2    1 
ATOM   13338 H HG3    . GLU B 1 391 ? -41.163 29.727  -36.307 1.00 97.48  ? 391 GLU B HG3    1 
ATOM   13339 N N      . THR B 1 392 ? -38.884 32.254  -39.690 1.00 61.42  ? 392 THR B N      1 
ATOM   13340 C CA     . THR B 1 392 ? -38.508 33.282  -40.654 1.00 56.86  ? 392 THR B CA     1 
ATOM   13341 C C      . THR B 1 392 ? -37.650 32.711  -41.782 1.00 55.18  ? 392 THR B C      1 
ATOM   13342 O O      . THR B 1 392 ? -37.699 33.190  -42.915 1.00 55.45  ? 392 THR B O      1 
ATOM   13343 C CB     . THR B 1 392 ? -37.736 34.431  -39.970 1.00 58.87  ? 392 THR B CB     1 
ATOM   13344 O OG1    . THR B 1 392 ? -36.450 33.964  -39.549 1.00 53.08  ? 392 THR B OG1    1 
ATOM   13345 C CG2    . THR B 1 392 ? -38.505 34.960  -38.759 1.00 54.74  ? 392 THR B CG2    1 
ATOM   13346 H H      . THR B 1 392 ? -38.545 32.369  -38.908 1.00 73.70  ? 392 THR B H      1 
ATOM   13347 H HA     . THR B 1 392 ? -39.312 33.654  -41.048 1.00 68.23  ? 392 THR B HA     1 
ATOM   13348 H HB     . THR B 1 392 ? -37.622 35.160  -40.600 1.00 70.65  ? 392 THR B HB     1 
ATOM   13349 H HG1    . THR B 1 392 ? -36.026 34.586  -39.176 1.00 63.70  ? 392 THR B HG1    1 
ATOM   13350 H HG21   . THR B 1 392 ? -38.075 35.760  -38.418 1.00 65.69  ? 392 THR B HG21   1 
ATOM   13351 H HG22   . THR B 1 392 ? -39.415 35.177  -39.014 1.00 65.69  ? 392 THR B HG22   1 
ATOM   13352 H HG23   . THR B 1 392 ? -38.525 34.290  -38.058 1.00 65.69  ? 392 THR B HG23   1 
ATOM   13353 N N      . GLY B 1 393 ? -36.865 31.685  -41.466 1.00 51.99  ? 393 GLY B N      1 
ATOM   13354 C CA     . GLY B 1 393 ? -35.941 31.111  -42.427 1.00 43.63  ? 393 GLY B CA     1 
ATOM   13355 C C      . GLY B 1 393 ? -34.668 31.930  -42.557 1.00 43.69  ? 393 GLY B C      1 
ATOM   13356 O O      . GLY B 1 393 ? -33.818 31.646  -43.403 1.00 38.37  ? 393 GLY B O      1 
ATOM   13357 H H      . GLY B 1 393 ? -36.851 31.303  -40.695 1.00 62.38  ? 393 GLY B H      1 
ATOM   13358 H HA2    . GLY B 1 393 ? -35.701 30.213  -42.148 1.00 52.35  ? 393 GLY B HA2    1 
ATOM   13359 H HA3    . GLY B 1 393 ? -36.365 31.059  -43.298 1.00 52.35  ? 393 GLY B HA3    1 
ATOM   13360 N N      . ASP B 1 394 ? -34.542 32.951  -41.715 1.00 39.96  ? 394 ASP B N      1 
ATOM   13361 C CA     . ASP B 1 394 ? -33.365 33.811  -41.697 1.00 42.36  ? 394 ASP B CA     1 
ATOM   13362 C C      . ASP B 1 394 ? -32.360 33.291  -40.665 1.00 42.15  ? 394 ASP B C      1 
ATOM   13363 O O      . ASP B 1 394 ? -32.709 32.463  -39.819 1.00 36.81  ? 394 ASP B O      1 
ATOM   13364 C CB     . ASP B 1 394 ? -33.779 35.252  -41.375 1.00 43.30  ? 394 ASP B CB     1 
ATOM   13365 C CG     . ASP B 1 394 ? -32.674 36.263  -41.635 1.00 45.71  ? 394 ASP B CG     1 
ATOM   13366 O OD1    . ASP B 1 394 ? -31.678 35.936  -42.318 1.00 39.13  ? 394 ASP B OD1    1 
ATOM   13367 O OD2    . ASP B 1 394 ? -32.816 37.408  -41.157 1.00 50.81  ? 394 ASP B OD2    1 
ATOM   13368 H H      . ASP B 1 394 ? -35.133 33.173  -41.132 1.00 47.96  ? 394 ASP B H      1 
ATOM   13369 H HA     . ASP B 1 394 ? -32.942 33.801  -42.570 1.00 50.83  ? 394 ASP B HA     1 
ATOM   13370 H HB2    . ASP B 1 394 ? -34.539 35.492  -41.927 1.00 51.96  ? 394 ASP B HB2    1 
ATOM   13371 H HB3    . ASP B 1 394 ? -34.021 35.308  -40.437 1.00 51.96  ? 394 ASP B HB3    1 
ATOM   13372 N N      . HIS B 1 395 ? -31.119 33.765  -40.742 1.00 38.30  ? 395 HIS B N      1 
ATOM   13373 C CA     . HIS B 1 395 ? -30.123 33.447  -39.722 1.00 34.04  ? 395 HIS B CA     1 
ATOM   13374 C C      . HIS B 1 395 ? -30.617 33.871  -38.355 1.00 35.40  ? 395 HIS B C      1 
ATOM   13375 O O      . HIS B 1 395 ? -31.250 34.917  -38.228 1.00 37.34  ? 395 HIS B O      1 
ATOM   13376 C CB     . HIS B 1 395 ? -28.792 34.163  -39.975 1.00 35.81  ? 395 HIS B CB     1 
ATOM   13377 C CG     . HIS B 1 395 ? -28.169 33.871  -41.301 1.00 37.64  ? 395 HIS B CG     1 
ATOM   13378 N ND1    . HIS B 1 395 ? -27.784 32.605  -41.683 1.00 38.71  ? 395 HIS B ND1    1 
ATOM   13379 C CD2    . HIS B 1 395 ? -27.825 34.694  -42.319 1.00 41.28  ? 395 HIS B CD2    1 
ATOM   13380 C CE1    . HIS B 1 395 ? -27.246 32.657  -42.889 1.00 41.65  ? 395 HIS B CE1    1 
ATOM   13381 N NE2    . HIS B 1 395 ? -27.262 33.914  -43.298 1.00 44.04  ? 395 HIS B NE2    1 
ATOM   13382 H H      . HIS B 1 395 ? -30.829 34.272  -41.373 1.00 45.96  ? 395 HIS B H      1 
ATOM   13383 H HA     . HIS B 1 395 ? -29.963 32.490  -39.711 1.00 40.85  ? 395 HIS B HA     1 
ATOM   13384 H HB2    . HIS B 1 395 ? -28.941 35.120  -39.925 1.00 42.98  ? 395 HIS B HB2    1 
ATOM   13385 H HB3    . HIS B 1 395 ? -28.161 33.895  -39.289 1.00 42.98  ? 395 HIS B HB3    1 
ATOM   13386 H HD2    . HIS B 1 395 ? -27.957 35.614  -42.354 1.00 49.54  ? 395 HIS B HD2    1 
ATOM   13387 H HE1    . HIS B 1 395 ? -26.916 31.932  -43.370 1.00 49.98  ? 395 HIS B HE1    1 
ATOM   13388 H HE2    . HIS B 1 395 ? -26.966 34.197  -44.054 1.00 52.85  ? 395 HIS B HE2    1 
ATOM   13389 N N      . HIS B 1 396 ? -30.325 33.068  -37.336 1.00 34.58  ? 396 HIS B N      1 
ATOM   13390 C CA     . HIS B 1 396 ? -30.237 33.597  -35.983 1.00 35.71  ? 396 HIS B CA     1 
ATOM   13391 C C      . HIS B 1 396 ? -29.017 34.497  -35.978 1.00 36.64  ? 396 HIS B C      1 
ATOM   13392 O O      . HIS B 1 396 ? -28.032 34.195  -36.648 1.00 33.38  ? 396 HIS B O      1 
ATOM   13393 C CB     . HIS B 1 396 ? -30.093 32.494  -34.939 1.00 37.33  ? 396 HIS B CB     1 
ATOM   13394 C CG     . HIS B 1 396 ? -31.362 31.753  -34.655 1.00 41.39  ? 396 HIS B CG     1 
ATOM   13395 N ND1    . HIS B 1 396 ? -31.437 30.377  -34.665 1.00 43.89  ? 396 HIS B ND1    1 
ATOM   13396 C CD2    . HIS B 1 396 ? -32.600 32.198  -34.337 1.00 46.14  ? 396 HIS B CD2    1 
ATOM   13397 C CE1    . HIS B 1 396 ? -32.672 30.005  -34.373 1.00 44.99  ? 396 HIS B CE1    1 
ATOM   13398 N NE2    . HIS B 1 396 ? -33.397 31.090  -34.170 1.00 51.15  ? 396 HIS B NE2    1 
ATOM   13399 H H      . HIS B 1 396 ? -30.175 32.224  -37.401 1.00 41.50  ? 396 HIS B H      1 
ATOM   13400 H HA     . HIS B 1 396 ? -31.024 34.127  -35.779 1.00 42.85  ? 396 HIS B HA     1 
ATOM   13401 H HB2    . HIS B 1 396 ? -29.438 31.851  -35.253 1.00 44.79  ? 396 HIS B HB2    1 
ATOM   13402 H HB3    . HIS B 1 396 ? -29.790 32.891  -34.107 1.00 44.79  ? 396 HIS B HB3    1 
ATOM   13403 H HD1    . HIS B 1 396 ? -30.784 29.844  -34.837 1.00 52.67  ? 396 HIS B HD1    1 
ATOM   13404 H HD2    . HIS B 1 396 ? -32.863 33.086  -34.252 1.00 55.37  ? 396 HIS B HD2    1 
ATOM   13405 H HE1    . HIS B 1 396 ? -32.978 29.128  -34.320 1.00 53.99  ? 396 HIS B HE1    1 
ATOM   13406 N N      . ARG B 1 397 ? -29.080 35.605  -35.249 1.00 35.58  ? 397 ARG B N      1 
ATOM   13407 C CA     . ARG B 1 397 ? -27.968 36.548  -35.207 1.00 36.01  ? 397 ARG B CA     1 
ATOM   13408 C C      . ARG B 1 397 ? -27.558 36.768  -33.758 1.00 39.60  ? 397 ARG B C      1 
ATOM   13409 O O      . ARG B 1 397 ? -28.022 37.708  -33.110 1.00 32.55  ? 397 ARG B O      1 
ATOM   13410 C CB     . ARG B 1 397 ? -28.346 37.869  -35.893 1.00 36.60  ? 397 ARG B CB     1 
ATOM   13411 C CG     . ARG B 1 397 ? -28.557 37.707  -37.401 1.00 34.74  ? 397 ARG B CG     1 
ATOM   13412 C CD     . ARG B 1 397 ? -28.660 39.036  -38.147 1.00 30.88  ? 397 ARG B CD     1 
ATOM   13413 N NE     . ARG B 1 397 ? -28.634 38.825  -39.595 1.00 27.61  ? 397 ARG B NE     1 
ATOM   13414 C CZ     . ARG B 1 397 ? -29.664 38.357  -40.293 1.00 32.37  ? 397 ARG B CZ     1 
ATOM   13415 N NH1    . ARG B 1 397 ? -30.803 38.074  -39.680 1.00 36.29  ? 397 ARG B NH1    1 
ATOM   13416 N NH2    . ARG B 1 397 ? -29.563 38.174  -41.602 1.00 35.34  ? 397 ARG B NH2    1 
ATOM   13417 H H      . ARG B 1 397 ? -29.756 35.835  -34.769 1.00 42.69  ? 397 ARG B H      1 
ATOM   13418 H HA     . ARG B 1 397 ? -27.209 36.191  -35.689 1.00 43.22  ? 397 ARG B HA     1 
ATOM   13419 H HB2    . ARG B 1 397 ? -29.172 38.201  -35.508 1.00 43.92  ? 397 ARG B HB2    1 
ATOM   13420 H HB3    . ARG B 1 397 ? -27.633 38.512  -35.756 1.00 43.92  ? 397 ARG B HB3    1 
ATOM   13421 H HG2    . ARG B 1 397 ? -27.808 37.215  -37.771 1.00 41.69  ? 397 ARG B HG2    1 
ATOM   13422 H HG3    . ARG B 1 397 ? -29.380 37.216  -37.551 1.00 41.69  ? 397 ARG B HG3    1 
ATOM   13423 H HD2    . ARG B 1 397 ? -29.493 39.475  -37.914 1.00 37.05  ? 397 ARG B HD2    1 
ATOM   13424 H HD3    . ARG B 1 397 ? -27.906 39.597  -37.908 1.00 37.05  ? 397 ARG B HD3    1 
ATOM   13425 H HE     . ARG B 1 397 ? -27.883 38.923  -40.003 1.00 33.13  ? 397 ARG B HE     1 
ATOM   13426 H HH11   . ARG B 1 397 ? -30.879 38.184  -38.831 1.00 43.55  ? 397 ARG B HH11   1 
ATOM   13427 H HH12   . ARG B 1 397 ? -31.468 37.776  -40.131 1.00 43.55  ? 397 ARG B HH12   1 
ATOM   13428 H HH21   . ARG B 1 397 ? -28.828 38.361  -42.007 1.00 42.40  ? 397 ARG B HH21   1 
ATOM   13429 H HH22   . ARG B 1 397 ? -30.237 37.880  -42.048 1.00 42.40  ? 397 ARG B HH22   1 
ATOM   13430 N N      . PRO B 1 398 ? -26.682 35.888  -33.237 1.00 32.10  ? 398 PRO B N      1 
ATOM   13431 C CA     . PRO B 1 398 ? -26.344 35.944  -31.810 1.00 34.48  ? 398 PRO B CA     1 
ATOM   13432 C C      . PRO B 1 398 ? -25.480 37.144  -31.461 1.00 35.72  ? 398 PRO B C      1 
ATOM   13433 O O      . PRO B 1 398 ? -24.725 37.630  -32.302 1.00 33.27  ? 398 PRO B O      1 
ATOM   13434 C CB     . PRO B 1 398 ? -25.575 34.641  -31.576 1.00 33.13  ? 398 PRO B CB     1 
ATOM   13435 C CG     . PRO B 1 398 ? -24.960 34.330  -32.914 1.00 34.93  ? 398 PRO B CG     1 
ATOM   13436 C CD     . PRO B 1 398 ? -25.956 34.812  -33.939 1.00 31.51  ? 398 PRO B CD     1 
ATOM   13437 H HA     . PRO B 1 398 ? -27.148 35.950  -31.267 1.00 41.38  ? 398 PRO B HA     1 
ATOM   13438 H HB2    . PRO B 1 398 ? -24.889 34.779  -30.904 1.00 39.75  ? 398 PRO B HB2    1 
ATOM   13439 H HB3    . PRO B 1 398 ? -26.189 33.940  -31.306 1.00 39.75  ? 398 PRO B HB3    1 
ATOM   13440 H HG2    . PRO B 1 398 ? -24.120 34.807  -33.004 1.00 41.91  ? 398 PRO B HG2    1 
ATOM   13441 H HG3    . PRO B 1 398 ? -24.819 33.374  -32.994 1.00 41.91  ? 398 PRO B HG3    1 
ATOM   13442 H HD2    . PRO B 1 398 ? -25.493 35.165  -34.715 1.00 37.81  ? 398 PRO B HD2    1 
ATOM   13443 H HD3    . PRO B 1 398 ? -26.564 34.096  -34.182 1.00 37.81  ? 398 PRO B HD3    1 
ATOM   13444 N N      . LYS B 1 399 ? -25.584 37.612  -30.225 1.00 37.18  ? 399 LYS B N      1 
ATOM   13445 C CA     . LYS B 1 399 ? -24.790 38.751  -29.796 1.00 43.49  ? 399 LYS B CA     1 
ATOM   13446 C C      . LYS B 1 399 ? -23.304 38.395  -29.763 1.00 36.56  ? 399 LYS B C      1 
ATOM   13447 O O      . LYS B 1 399 ? -22.460 39.215  -30.114 1.00 39.07  ? 399 LYS B O      1 
ATOM   13448 C CB     . LYS B 1 399 ? -25.259 39.249  -28.422 1.00 48.49  ? 399 LYS B CB     1 
ATOM   13449 C CG     . LYS B 1 399 ? -26.653 39.907  -28.431 1.00 73.11  ? 399 LYS B CG     1 
ATOM   13450 C CD     . LYS B 1 399 ? -26.796 40.982  -29.522 1.00 85.66  ? 399 LYS B CD     1 
ATOM   13451 C CE     . LYS B 1 399 ? -28.146 41.687  -29.467 1.00 81.22  ? 399 LYS B CE     1 
ATOM   13452 N NZ     . LYS B 1 399 ? -28.365 42.566  -30.657 1.00 85.77  ? 399 LYS B NZ     1 
ATOM   13453 H H      . LYS B 1 399 ? -26.103 37.290  -29.620 1.00 44.61  ? 399 LYS B H      1 
ATOM   13454 H HA     . LYS B 1 399 ? -24.893 39.467  -30.439 1.00 52.19  ? 399 LYS B HA     1 
ATOM   13455 H HB2    . LYS B 1 399 ? -25.292 38.495  -27.812 1.00 58.19  ? 399 LYS B HB2    1 
ATOM   13456 H HB3    . LYS B 1 399 ? -24.624 39.906  -28.096 1.00 58.19  ? 399 LYS B HB3    1 
ATOM   13457 H HG2    . LYS B 1 399 ? -27.323 39.225  -28.592 1.00 87.73  ? 399 LYS B HG2    1 
ATOM   13458 H HG3    . LYS B 1 399 ? -26.809 40.329  -27.572 1.00 87.73  ? 399 LYS B HG3    1 
ATOM   13459 H HD2    . LYS B 1 399 ? -26.100 41.648  -29.408 1.00 102.79 ? 399 LYS B HD2    1 
ATOM   13460 H HD3    . LYS B 1 399 ? -26.723 40.567  -30.395 1.00 102.79 ? 399 LYS B HD3    1 
ATOM   13461 H HE2    . LYS B 1 399 ? -28.852 41.022  -29.447 1.00 97.46  ? 399 LYS B HE2    1 
ATOM   13462 H HE3    . LYS B 1 399 ? -28.185 42.240  -28.671 1.00 97.46  ? 399 LYS B HE3    1 
ATOM   13463 H HZ1    . LYS B 1 399 ? -29.159 42.964  -30.599 1.00 102.92 ? 399 LYS B HZ1    1 
ATOM   13464 H HZ2    . LYS B 1 399 ? -27.731 43.189  -30.695 1.00 102.92 ? 399 LYS B HZ2    1 
ATOM   13465 H HZ3    . LYS B 1 399 ? -28.339 42.080  -31.402 1.00 102.92 ? 399 LYS B HZ3    1 
ATOM   13466 N N      . LEU B 1 400 ? -22.981 37.170  -29.367 1.00 32.41  ? 400 LEU B N      1 
ATOM   13467 C CA     . LEU B 1 400 ? -21.591 36.735  -29.366 1.00 36.09  ? 400 LEU B CA     1 
ATOM   13468 C C      . LEU B 1 400 ? -21.213 36.140  -30.717 1.00 28.52  ? 400 LEU B C      1 
ATOM   13469 O O      . LEU B 1 400 ? -21.772 35.134  -31.151 1.00 26.39  ? 400 LEU B O      1 
ATOM   13470 C CB     . LEU B 1 400 ? -21.336 35.726  -28.245 1.00 38.82  ? 400 LEU B CB     1 
ATOM   13471 C CG     . LEU B 1 400 ? -21.399 36.326  -26.834 1.00 48.98  ? 400 LEU B CG     1 
ATOM   13472 C CD1    . LEU B 1 400 ? -21.312 35.233  -25.777 1.00 46.48  ? 400 LEU B CD1    1 
ATOM   13473 C CD2    . LEU B 1 400 ? -20.298 37.371  -26.615 1.00 42.09  ? 400 LEU B CD2    1 
ATOM   13474 H H      . LEU B 1 400 ? -23.542 36.577  -29.097 1.00 38.89  ? 400 LEU B H      1 
ATOM   13475 H HA     . LEU B 1 400 ? -21.015 37.498  -29.211 1.00 43.31  ? 400 LEU B HA     1 
ATOM   13476 H HB2    . LEU B 1 400 ? -22.005 35.026  -28.298 1.00 46.59  ? 400 LEU B HB2    1 
ATOM   13477 H HB3    . LEU B 1 400 ? -20.452 35.344  -28.364 1.00 46.59  ? 400 LEU B HB3    1 
ATOM   13478 H HG     . LEU B 1 400 ? -22.253 36.772  -26.725 1.00 58.78  ? 400 LEU B HG     1 
ATOM   13479 H HD11   . LEU B 1 400 ? -21.360 35.640  -24.898 1.00 55.78  ? 400 LEU B HD11   1 
ATOM   13480 H HD12   . LEU B 1 400 ? -22.052 34.618  -25.898 1.00 55.78  ? 400 LEU B HD12   1 
ATOM   13481 H HD13   . LEU B 1 400 ? -20.470 34.762  -25.879 1.00 55.78  ? 400 LEU B HD13   1 
ATOM   13482 H HD21   . LEU B 1 400 ? -20.255 37.590  -25.671 1.00 50.51  ? 400 LEU B HD21   1 
ATOM   13483 H HD22   . LEU B 1 400 ? -19.450 37.001  -26.907 1.00 50.51  ? 400 LEU B HD22   1 
ATOM   13484 H HD23   . LEU B 1 400 ? -20.508 38.165  -27.130 1.00 50.51  ? 400 LEU B HD23   1 
ATOM   13485 N N      . GLU B 1 401 ? -20.272 36.800  -31.377 1.00 24.30  ? 401 GLU B N      1 
ATOM   13486 C CA     . GLU B 1 401 ? -19.697 36.319  -32.631 1.00 26.07  ? 401 GLU B CA     1 
ATOM   13487 C C      . GLU B 1 401 ? -18.241 36.016  -32.335 1.00 24.52  ? 401 GLU B C      1 
ATOM   13488 O O      . GLU B 1 401 ? -17.391 36.898  -32.439 1.00 25.21  ? 401 GLU B O      1 
ATOM   13489 C CB     . GLU B 1 401 ? -19.842 37.367  -33.734 1.00 27.43  ? 401 GLU B CB     1 
ATOM   13490 C CG     . GLU B 1 401 ? -19.173 37.010  -35.067 1.00 26.63  ? 401 GLU B CG     1 
ATOM   13491 C CD     . GLU B 1 401 ? -19.971 36.020  -35.907 1.00 29.29  ? 401 GLU B CD     1 
ATOM   13492 O OE1    . GLU B 1 401 ? -19.460 35.596  -36.970 1.00 25.82  ? 401 GLU B OE1    1 
ATOM   13493 O OE2    . GLU B 1 401 ? -21.111 35.679  -35.525 1.00 23.41  ? 401 GLU B OE2    1 
ATOM   13494 H H      . GLU B 1 401 ? -19.940 37.548  -31.114 1.00 29.15  ? 401 GLU B H      1 
ATOM   13495 H HA     . GLU B 1 401 ? -20.134 35.502  -32.917 1.00 31.28  ? 401 GLU B HA     1 
ATOM   13496 H HB2    . GLU B 1 401 ? -20.786 37.512  -33.903 1.00 32.92  ? 401 GLU B HB2    1 
ATOM   13497 H HB3    . GLU B 1 401 ? -19.441 38.194  -33.423 1.00 32.92  ? 401 GLU B HB3    1 
ATOM   13498 H HG2    . GLU B 1 401 ? -19.073 37.823  -35.586 1.00 31.95  ? 401 GLU B HG2    1 
ATOM   13499 H HG3    . GLU B 1 401 ? -18.301 36.622  -34.897 1.00 31.95  ? 401 GLU B HG3    1 
ATOM   13500 N N      . THR B 1 402 ? -17.954 34.785  -31.921 1.00 21.70  ? 402 THR B N      1 
ATOM   13501 C CA     . THR B 1 402 ? -16.632 34.494  -31.375 1.00 25.20  ? 402 THR B CA     1 
ATOM   13502 C C      . THR B 1 402 ? -15.907 33.330  -32.046 1.00 20.05  ? 402 THR B C      1 
ATOM   13503 O O      . THR B 1 402 ? -16.513 32.450  -32.655 1.00 19.68  ? 402 THR B O      1 
ATOM   13504 C CB     . THR B 1 402 ? -16.702 34.195  -29.852 1.00 28.06  ? 402 THR B CB     1 
ATOM   13505 O OG1    . THR B 1 402 ? -17.336 32.931  -29.626 1.00 28.53  ? 402 THR B OG1    1 
ATOM   13506 C CG2    . THR B 1 402 ? -17.468 35.286  -29.119 1.00 31.59  ? 402 THR B CG2    1 
ATOM   13507 H H      . THR B 1 402 ? -18.493 34.115  -31.944 1.00 26.04  ? 402 THR B H      1 
ATOM   13508 H HA     . THR B 1 402 ? -16.072 35.270  -31.491 1.00 30.24  ? 402 THR B HA     1 
ATOM   13509 H HB     . THR B 1 402 ? -15.801 34.166  -29.493 1.00 33.68  ? 402 THR B HB     1 
ATOM   13510 H HG1    . THR B 1 402 ? -18.116 32.941  -29.937 1.00 34.23  ? 402 THR B HG1    1 
ATOM   13511 H HG21   . THR B 1 402 ? -17.446 35.121  -28.163 1.00 37.91  ? 402 THR B HG21   1 
ATOM   13512 H HG22   . THR B 1 402 ? -17.066 36.150  -29.299 1.00 37.91  ? 402 THR B HG22   1 
ATOM   13513 H HG23   . THR B 1 402 ? -18.391 35.300  -29.415 1.00 37.91  ? 402 THR B HG23   1 
ATOM   13514 N N      . VAL B 1 403 ? -14.585 33.381  -31.939 1.00 21.54  ? 403 VAL B N      1 
ATOM   13515 C CA     . VAL B 1 403 ? -13.721 32.258  -32.267 1.00 19.78  ? 403 VAL B CA     1 
ATOM   13516 C C      . VAL B 1 403 ? -13.138 31.756  -30.950 1.00 17.41  ? 403 VAL B C      1 
ATOM   13517 O O      . VAL B 1 403 ? -12.510 32.515  -30.213 1.00 18.79  ? 403 VAL B O      1 
ATOM   13518 C CB     . VAL B 1 403 ? -12.611 32.664  -33.244 1.00 19.14  ? 403 VAL B CB     1 
ATOM   13519 C CG1    . VAL B 1 403 ? -11.628 31.528  -33.447 1.00 19.09  ? 403 VAL B CG1    1 
ATOM   13520 C CG2    . VAL B 1 403 ? -13.216 33.096  -34.599 1.00 21.41  ? 403 VAL B CG2    1 
ATOM   13521 H H      . VAL B 1 403 ? -14.155 34.076  -31.671 1.00 25.84  ? 403 VAL B H      1 
ATOM   13522 H HA     . VAL B 1 403 ? -14.238 31.543  -32.668 1.00 23.74  ? 403 VAL B HA     1 
ATOM   13523 H HB     . VAL B 1 403 ? -12.126 33.419  -32.877 1.00 22.97  ? 403 VAL B HB     1 
ATOM   13524 H HG11   . VAL B 1 403 ? -11.080 31.723  -34.223 1.00 22.91  ? 403 VAL B HG11   1 
ATOM   13525 H HG12   . VAL B 1 403 ? -11.067 31.447  -32.660 1.00 22.91  ? 403 VAL B HG12   1 
ATOM   13526 H HG13   . VAL B 1 403 ? -12.122 30.706  -33.591 1.00 22.91  ? 403 VAL B HG13   1 
ATOM   13527 H HG21   . VAL B 1 403 ? -12.497 33.342  -35.201 1.00 25.69  ? 403 VAL B HG21   1 
ATOM   13528 H HG22   . VAL B 1 403 ? -13.719 32.355  -34.970 1.00 25.69  ? 403 VAL B HG22   1 
ATOM   13529 H HG23   . VAL B 1 403 ? -13.802 33.855  -34.455 1.00 25.69  ? 403 VAL B HG23   1 
ATOM   13530 N N      . ARG B 1 404 ? -13.367 30.482  -30.653 1.00 16.83  ? 404 ARG B N      1 
ATOM   13531 C CA     . ARG B 1 404 ? -12.956 29.915  -29.377 1.00 19.03  ? 404 ARG B CA     1 
ATOM   13532 C C      . ARG B 1 404 ? -11.647 29.166  -29.527 1.00 16.84  ? 404 ARG B C      1 
ATOM   13533 O O      . ARG B 1 404 ? -11.552 28.221  -30.309 1.00 18.34  ? 404 ARG B O      1 
ATOM   13534 C CB     . ARG B 1 404 ? -14.033 28.982  -28.827 1.00 17.01  ? 404 ARG B CB     1 
ATOM   13535 C CG     . ARG B 1 404 ? -13.829 28.614  -27.372 1.00 18.78  ? 404 ARG B CG     1 
ATOM   13536 C CD     . ARG B 1 404 ? -14.929 27.676  -26.899 1.00 18.95  ? 404 ARG B CD     1 
ATOM   13537 N NE     . ARG B 1 404 ? -14.782 26.337  -27.455 1.00 19.37  ? 404 ARG B NE     1 
ATOM   13538 C CZ     . ARG B 1 404 ? -15.764 25.442  -27.523 1.00 20.20  ? 404 ARG B CZ     1 
ATOM   13539 N NH1    . ARG B 1 404 ? -16.986 25.745  -27.091 1.00 21.36  ? 404 ARG B NH1    1 
ATOM   13540 N NH2    . ARG B 1 404 ? -15.528 24.245  -28.031 1.00 24.43  ? 404 ARG B NH2    1 
ATOM   13541 H H      . ARG B 1 404 ? -13.760 29.924  -31.176 1.00 20.19  ? 404 ARG B H      1 
ATOM   13542 H HA     . ARG B 1 404 ? -12.824 30.625  -28.730 1.00 22.83  ? 404 ARG B HA     1 
ATOM   13543 H HB2    . ARG B 1 404 ? -14.896 29.419  -28.905 1.00 20.42  ? 404 ARG B HB2    1 
ATOM   13544 H HB3    . ARG B 1 404 ? -14.031 28.162  -29.344 1.00 20.42  ? 404 ARG B HB3    1 
ATOM   13545 H HG2    . ARG B 1 404 ? -12.977 28.162  -27.270 1.00 22.54  ? 404 ARG B HG2    1 
ATOM   13546 H HG3    . ARG B 1 404 ? -13.853 29.417  -26.829 1.00 22.54  ? 404 ARG B HG3    1 
ATOM   13547 H HD2    . ARG B 1 404 ? -14.896 27.608  -25.932 1.00 22.73  ? 404 ARG B HD2    1 
ATOM   13548 H HD3    . ARG B 1 404 ? -15.787 28.031  -27.181 1.00 22.73  ? 404 ARG B HD3    1 
ATOM   13549 H HE     . ARG B 1 404 ? -14.010 26.111  -27.759 1.00 23.25  ? 404 ARG B HE     1 
ATOM   13550 H HH11   . ARG B 1 404 ? -17.148 26.519  -26.755 1.00 25.63  ? 404 ARG B HH11   1 
ATOM   13551 H HH12   . ARG B 1 404 ? -17.615 25.161  -27.142 1.00 25.63  ? 404 ARG B HH12   1 
ATOM   13552 H HH21   . ARG B 1 404 ? -14.741 24.047  -28.317 1.00 29.32  ? 404 ARG B HH21   1 
ATOM   13553 H HH22   . ARG B 1 404 ? -16.163 23.668  -28.085 1.00 29.32  ? 404 ARG B HH22   1 
ATOM   13554 N N      . LEU B 1 405 ? -10.641 29.638  -28.802 1.00 16.31  ? 405 LEU B N      1 
ATOM   13555 C CA     . LEU B 1 405 ? -9.367  28.962  -28.670 1.00 16.81  ? 405 LEU B CA     1 
ATOM   13556 C C      . LEU B 1 405 ? -9.415  28.117  -27.398 1.00 19.35  ? 405 LEU B C      1 
ATOM   13557 O O      . LEU B 1 405 ? -9.161  28.633  -26.309 1.00 17.96  ? 405 LEU B O      1 
ATOM   13558 C CB     . LEU B 1 405 ? -8.226  29.974  -28.602 1.00 16.43  ? 405 LEU B CB     1 
ATOM   13559 C CG     . LEU B 1 405 ? -8.231  31.090  -29.662 1.00 19.24  ? 405 LEU B CG     1 
ATOM   13560 C CD1    . LEU B 1 405 ? -7.193  32.159  -29.340 1.00 17.76  ? 405 LEU B CD1    1 
ATOM   13561 C CD2    . LEU B 1 405 ? -7.984  30.500  -31.025 1.00 19.42  ? 405 LEU B CD2    1 
ATOM   13562 H H      . LEU B 1 405 ? -10.679 30.376  -28.363 1.00 19.57  ? 405 LEU B H      1 
ATOM   13563 H HA     . LEU B 1 405 ? -9.219  28.377  -29.429 1.00 20.17  ? 405 LEU B HA     1 
ATOM   13564 H HB2    . LEU B 1 405 ? -8.251  30.410  -27.736 1.00 19.72  ? 405 LEU B HB2    1 
ATOM   13565 H HB3    . LEU B 1 405 ? -7.389  29.493  -28.695 1.00 19.72  ? 405 LEU B HB3    1 
ATOM   13566 H HG     . LEU B 1 405 ? -9.103  31.515  -29.673 1.00 23.09  ? 405 LEU B HG     1 
ATOM   13567 H HD11   . LEU B 1 405 ? -7.231  32.850  -30.019 1.00 21.31  ? 405 LEU B HD11   1 
ATOM   13568 H HD12   . LEU B 1 405 ? -7.391  32.539  -28.470 1.00 21.31  ? 405 LEU B HD12   1 
ATOM   13569 H HD13   . LEU B 1 405 ? -6.313  31.751  -29.331 1.00 21.31  ? 405 LEU B HD13   1 
ATOM   13570 H HD21   . LEU B 1 405 ? -7.966  31.215  -31.680 1.00 23.30  ? 405 LEU B HD21   1 
ATOM   13571 H HD22   . LEU B 1 405 ? -7.132  30.035  -31.018 1.00 23.30  ? 405 LEU B HD22   1 
ATOM   13572 H HD23   . LEU B 1 405 ? -8.699  29.879  -31.233 1.00 23.30  ? 405 LEU B HD23   1 
ATOM   13573 N N      . THR B 1 406 ? -9.752  26.836  -27.541 1.00 17.53  ? 406 THR B N      1 
ATOM   13574 C CA     . THR B 1 406 ? -10.028 25.971  -26.393 1.00 12.97  ? 406 THR B CA     1 
ATOM   13575 C C      . THR B 1 406 ? -8.818  25.082  -26.097 1.00 18.29  ? 406 THR B C      1 
ATOM   13576 O O      . THR B 1 406 ? -8.335  24.389  -26.986 1.00 17.64  ? 406 THR B O      1 
ATOM   13577 C CB     . THR B 1 406 ? -11.276 25.083  -26.639 1.00 18.60  ? 406 THR B CB     1 
ATOM   13578 O OG1    . THR B 1 406 ? -12.077 25.625  -27.695 1.00 19.76  ? 406 THR B OG1    1 
ATOM   13579 C CG2    . THR B 1 406 ? -12.122 24.987  -25.394 1.00 17.59  ? 406 THR B CG2    1 
ATOM   13580 H H      . THR B 1 406 ? -9.828  26.440  -28.300 1.00 21.04  ? 406 THR B H      1 
ATOM   13581 H HA     . THR B 1 406 ? -10.201 26.516  -25.610 1.00 15.56  ? 406 THR B HA     1 
ATOM   13582 H HB     . THR B 1 406 ? -10.985 24.191  -26.881 1.00 22.32  ? 406 THR B HB     1 
ATOM   13583 H HG1    . THR B 1 406 ? -11.659 25.587  -28.422 1.00 23.71  ? 406 THR B HG1    1 
ATOM   13584 H HG21   . THR B 1 406 ? -12.831 24.337  -25.524 1.00 21.11  ? 406 THR B HG21   1 
ATOM   13585 H HG22   . THR B 1 406 ? -11.575 24.710  -24.642 1.00 21.11  ? 406 THR B HG22   1 
ATOM   13586 H HG23   . THR B 1 406 ? -12.518 25.850  -25.195 1.00 21.11  ? 406 THR B HG23   1 
ATOM   13587 N N      . ILE B 1 407 ? -8.337  25.090  -24.851 1.00 15.21  ? 407 ILE B N      1 
ATOM   13588 C CA     . ILE B 1 407 ? -7.043  24.494  -24.539 1.00 14.16  ? 407 ILE B CA     1 
ATOM   13589 C C      . ILE B 1 407 ? -7.194  23.136  -23.853 1.00 15.10  ? 407 ILE B C      1 
ATOM   13590 O O      . ILE B 1 407 ? -7.646  23.073  -22.716 1.00 16.64  ? 407 ILE B O      1 
ATOM   13591 C CB     . ILE B 1 407 ? -6.207  25.425  -23.638 1.00 17.34  ? 407 ILE B CB     1 
ATOM   13592 C CG1    . ILE B 1 407 ? -6.211  26.866  -24.180 1.00 14.69  ? 407 ILE B CG1    1 
ATOM   13593 C CG2    . ILE B 1 407 ? -4.793  24.915  -23.502 1.00 17.21  ? 407 ILE B CG2    1 
ATOM   13594 C CD1    . ILE B 1 407 ? -5.861  26.994  -25.656 1.00 19.58  ? 407 ILE B CD1    1 
ATOM   13595 H H      . ILE B 1 407 ? -8.741  25.433  -24.174 1.00 18.25  ? 407 ILE B H      1 
ATOM   13596 H HA     . ILE B 1 407 ? -6.541  24.377  -25.358 1.00 17.00  ? 407 ILE B HA     1 
ATOM   13597 H HB     . ILE B 1 407 ? -6.610  25.435  -22.756 1.00 20.81  ? 407 ILE B HB     1 
ATOM   13598 H HG12   . ILE B 1 407 ? -7.096  27.242  -24.054 1.00 17.62  ? 407 ILE B HG12   1 
ATOM   13599 H HG13   . ILE B 1 407 ? -5.563  27.386  -23.680 1.00 17.62  ? 407 ILE B HG13   1 
ATOM   13600 H HG21   . ILE B 1 407 ? -4.259  25.586  -23.048 1.00 20.65  ? 407 ILE B HG21   1 
ATOM   13601 H HG22   . ILE B 1 407 ? -4.799  24.094  -22.985 1.00 20.65  ? 407 ILE B HG22   1 
ATOM   13602 H HG23   . ILE B 1 407 ? -4.431  24.748  -24.386 1.00 20.65  ? 407 ILE B HG23   1 
ATOM   13603 H HD11   . ILE B 1 407 ? -5.732  27.932  -25.868 1.00 23.50  ? 407 ILE B HD11   1 
ATOM   13604 H HD12   . ILE B 1 407 ? -5.045  26.500  -25.830 1.00 23.50  ? 407 ILE B HD12   1 
ATOM   13605 H HD13   . ILE B 1 407 ? -6.586  26.632  -26.188 1.00 23.50  ? 407 ILE B HD13   1 
ATOM   13606 N N      . PRO B 1 408 ? -6.819  22.039  -24.545 1.00 17.92  ? 408 PRO B N      1 
ATOM   13607 C CA     . PRO B 1 408 ? -6.790  20.730  -23.879 1.00 17.10  ? 408 PRO B CA     1 
ATOM   13608 C C      . PRO B 1 408 ? -5.785  20.718  -22.734 1.00 15.37  ? 408 PRO B C      1 
ATOM   13609 O O      . PRO B 1 408 ? -4.818  21.475  -22.771 1.00 16.42  ? 408 PRO B O      1 
ATOM   13610 C CB     . PRO B 1 408 ? -6.361  19.765  -24.994 1.00 15.81  ? 408 PRO B CB     1 
ATOM   13611 C CG     . PRO B 1 408 ? -6.694  20.468  -26.271 1.00 15.43  ? 408 PRO B CG     1 
ATOM   13612 C CD     . PRO B 1 408 ? -6.449  21.927  -25.965 1.00 16.38  ? 408 PRO B CD     1 
ATOM   13613 H HA     . PRO B 1 408 ? -7.670  20.487  -23.552 1.00 20.52  ? 408 PRO B HA     1 
ATOM   13614 H HB2    . PRO B 1 408 ? -5.407  19.602  -24.933 1.00 18.97  ? 408 PRO B HB2    1 
ATOM   13615 H HB3    . PRO B 1 408 ? -6.855  18.935  -24.917 1.00 18.97  ? 408 PRO B HB3    1 
ATOM   13616 H HG2    . PRO B 1 408 ? -6.107  20.160  -26.979 1.00 18.51  ? 408 PRO B HG2    1 
ATOM   13617 H HG3    . PRO B 1 408 ? -7.624  20.315  -26.500 1.00 18.51  ? 408 PRO B HG3    1 
ATOM   13618 H HD2    . PRO B 1 408 ? -5.513  22.147  -26.090 1.00 19.65  ? 408 PRO B HD2    1 
ATOM   13619 H HD3    . PRO B 1 408 ? -7.021  22.479  -26.515 1.00 19.65  ? 408 PRO B HD3    1 
ATOM   13620 N N      . ARG B 1 409 ? -6.008  19.867  -21.735 1.00 14.85  ? 409 ARG B N      1 
ATOM   13621 C CA     . ARG B 1 409 ? -5.121  19.802  -20.588 1.00 14.26  ? 409 ARG B CA     1 
ATOM   13622 C C      . ARG B 1 409 ? -3.889  18.951  -20.874 1.00 15.75  ? 409 ARG B C      1 
ATOM   13623 O O      . ARG B 1 409 ? -4.001  17.801  -21.307 1.00 14.56  ? 409 ARG B O      1 
ATOM   13624 C CB     . ARG B 1 409 ? -5.877  19.258  -19.367 1.00 14.80  ? 409 ARG B CB     1 
ATOM   13625 C CG     . ARG B 1 409 ? -7.062  20.125  -18.988 1.00 13.98  ? 409 ARG B CG     1 
ATOM   13626 C CD     . ARG B 1 409 ? -8.126  19.425  -18.154 1.00 16.71  ? 409 ARG B CD     1 
ATOM   13627 N NE     . ARG B 1 409 ? -9.280  20.310  -17.986 1.00 15.07  ? 409 ARG B NE     1 
ATOM   13628 C CZ     . ARG B 1 409 ? -10.221 20.494  -18.912 1.00 18.55  ? 409 ARG B CZ     1 
ATOM   13629 N NH1    . ARG B 1 409 ? -10.157 19.848  -20.072 1.00 16.31  ? 409 ARG B NH1    1 
ATOM   13630 N NH2    . ARG B 1 409 ? -11.221 21.339  -18.688 1.00 17.61  ? 409 ARG B NH2    1 
ATOM   13631 H H      . ARG B 1 409 ? -6.669  19.317  -21.702 1.00 17.82  ? 409 ARG B H      1 
ATOM   13632 H HA     . ARG B 1 409 ? -4.819  20.698  -20.372 1.00 17.11  ? 409 ARG B HA     1 
ATOM   13633 H HB2    . ARG B 1 409 ? -6.205  18.367  -19.566 1.00 17.76  ? 409 ARG B HB2    1 
ATOM   13634 H HB3    . ARG B 1 409 ? -5.273  19.228  -18.609 1.00 17.76  ? 409 ARG B HB3    1 
ATOM   13635 H HG2    . ARG B 1 409 ? -6.738  20.881  -18.473 1.00 16.78  ? 409 ARG B HG2    1 
ATOM   13636 H HG3    . ARG B 1 409 ? -7.491  20.443  -19.797 1.00 16.78  ? 409 ARG B HG3    1 
ATOM   13637 H HD2    . ARG B 1 409 ? -8.416  18.618  -18.607 1.00 20.05  ? 409 ARG B HD2    1 
ATOM   13638 H HD3    . ARG B 1 409 ? -7.773  19.211  -17.279 1.00 20.05  ? 409 ARG B HD3    1 
ATOM   13639 H HE     . ARG B 1 409 ? -9.385  20.694  -17.224 1.00 18.08  ? 409 ARG B HE     1 
ATOM   13640 H HH11   . ARG B 1 409 ? -9.510  19.306  -20.232 1.00 19.58  ? 409 ARG B HH11   1 
ATOM   13641 H HH12   . ARG B 1 409 ? -10.768 19.971  -20.664 1.00 19.58  ? 409 ARG B HH12   1 
ATOM   13642 H HH21   . ARG B 1 409 ? -11.271 21.757  -17.938 1.00 21.13  ? 409 ARG B HH21   1 
ATOM   13643 H HH22   . ARG B 1 409 ? -11.832 21.450  -19.283 1.00 21.13  ? 409 ARG B HH22   1 
ATOM   13644 N N      . ARG B 1 410 ? -2.722  19.549  -20.628 1.00 12.62  ? 410 ARG B N      1 
ATOM   13645 C CA     . ARG B 1 410 ? -1.429  18.869  -20.651 1.00 14.92  ? 410 ARG B CA     1 
ATOM   13646 C C      . ARG B 1 410 ? -0.985  18.417  -22.046 1.00 15.97  ? 410 ARG B C      1 
ATOM   13647 O O      . ARG B 1 410 ? -0.142  17.530  -22.165 1.00 19.64  ? 410 ARG B O      1 
ATOM   13648 C CB     . ARG B 1 410 ? -1.442  17.657  -19.692 1.00 15.07  ? 410 ARG B CB     1 
ATOM   13649 C CG     . ARG B 1 410 ? -1.792  18.024  -18.244 1.00 17.58  ? 410 ARG B CG     1 
ATOM   13650 C CD     . ARG B 1 410 ? -1.445  16.905  -17.258 1.00 18.39  ? 410 ARG B CD     1 
ATOM   13651 N NE     . ARG B 1 410 ? -2.171  15.675  -17.546 1.00 14.31  ? 410 ARG B NE     1 
ATOM   13652 C CZ     . ARG B 1 410 ? -2.366  14.687  -16.676 1.00 16.14  ? 410 ARG B CZ     1 
ATOM   13653 N NH1    . ARG B 1 410 ? -1.905  14.779  -15.429 1.00 18.70  ? 410 ARG B NH1    1 
ATOM   13654 N NH2    . ARG B 1 410 ? -3.043  13.613  -17.045 1.00 17.06  ? 410 ARG B NH2    1 
ATOM   13655 H H      . ARG B 1 410 ? -2.654  20.385  -20.437 1.00 15.15  ? 410 ARG B H      1 
ATOM   13656 H HA     . ARG B 1 410 ? -0.759  19.488  -20.326 1.00 17.91  ? 410 ARG B HA     1 
ATOM   13657 H HB2    . ARG B 1 410 ? -2.090  17.007  -20.002 1.00 18.09  ? 410 ARG B HB2    1 
ATOM   13658 H HB3    . ARG B 1 410 ? -0.558  17.257  -19.684 1.00 18.09  ? 410 ARG B HB3    1 
ATOM   13659 H HG2    . ARG B 1 410 ? -1.294  18.816  -17.988 1.00 21.09  ? 410 ARG B HG2    1 
ATOM   13660 H HG3    . ARG B 1 410 ? -2.745  18.195  -18.182 1.00 21.09  ? 410 ARG B HG3    1 
ATOM   13661 H HD2    . ARG B 1 410 ? -0.495  16.715  -17.313 1.00 22.07  ? 410 ARG B HD2    1 
ATOM   13662 H HD3    . ARG B 1 410 ? -1.677  17.192  -16.361 1.00 22.07  ? 410 ARG B HD3    1 
ATOM   13663 H HE     . ARG B 1 410 ? -2.499  15.582  -18.335 1.00 17.17  ? 410 ARG B HE     1 
ATOM   13664 H HH11   . ARG B 1 410 ? -1.465  15.474  -15.180 1.00 22.44  ? 410 ARG B HH11   1 
ATOM   13665 H HH12   . ARG B 1 410 ? -2.040  14.136  -14.874 1.00 22.44  ? 410 ARG B HH12   1 
ATOM   13666 H HH21   . ARG B 1 410 ? -3.346  13.550  -17.847 1.00 20.47  ? 410 ARG B HH21   1 
ATOM   13667 H HH22   . ARG B 1 410 ? -3.175  12.974  -16.484 1.00 20.47  ? 410 ARG B HH22   1 
ATOM   13668 N N      . VAL B 1 411 ? -1.527  19.038  -23.091 1.00 14.06  ? 411 VAL B N      1 
ATOM   13669 C CA     . VAL B 1 411 ? -1.237  18.637  -24.471 1.00 12.62  ? 411 VAL B CA     1 
ATOM   13670 C C      . VAL B 1 411 ? -0.229  19.575  -25.142 1.00 14.16  ? 411 VAL B C      1 
ATOM   13671 O O      . VAL B 1 411 ? 0.609   19.132  -25.932 1.00 16.16  ? 411 VAL B O      1 
ATOM   13672 C CB     . VAL B 1 411 ? -2.523  18.592  -25.323 1.00 17.70  ? 411 VAL B CB     1 
ATOM   13673 C CG1    . VAL B 1 411 ? -2.217  18.323  -26.793 1.00 13.70  ? 411 VAL B CG1    1 
ATOM   13674 C CG2    . VAL B 1 411 ? -3.471  17.525  -24.799 1.00 15.56  ? 411 VAL B CG2    1 
ATOM   13675 H H      . VAL B 1 411 ? -2.071  19.701  -23.029 1.00 16.87  ? 411 VAL B H      1 
ATOM   13676 H HA     . VAL B 1 411 ? -0.859  17.745  -24.473 1.00 15.14  ? 411 VAL B HA     1 
ATOM   13677 H HB     . VAL B 1 411 ? -2.973  19.449  -25.262 1.00 21.24  ? 411 VAL B HB     1 
ATOM   13678 H HG11   . VAL B 1 411 ? -3.040  18.083  -27.246 1.00 16.44  ? 411 VAL B HG11   1 
ATOM   13679 H HG12   . VAL B 1 411 ? -1.842  19.122  -27.194 1.00 16.44  ? 411 VAL B HG12   1 
ATOM   13680 H HG13   . VAL B 1 411 ? -1.583  17.592  -26.854 1.00 16.44  ? 411 VAL B HG13   1 
ATOM   13681 H HG21   . VAL B 1 411 ? -4.269  17.519  -25.349 1.00 18.67  ? 411 VAL B HG21   1 
ATOM   13682 H HG22   . VAL B 1 411 ? -3.031  16.662  -24.843 1.00 18.67  ? 411 VAL B HG22   1 
ATOM   13683 H HG23   . VAL B 1 411 ? -3.704  17.732  -23.881 1.00 18.67  ? 411 VAL B HG23   1 
ATOM   13684 N N      . TYR B 1 412 ? -0.316  20.865  -24.835 1.00 14.40  ? 412 TYR B N      1 
ATOM   13685 C CA     . TYR B 1 412 ? 0.492   21.872  -25.541 1.00 12.52  ? 412 TYR B CA     1 
ATOM   13686 C C      . TYR B 1 412 ? 1.407   22.627  -24.579 1.00 17.00  ? 412 TYR B C      1 
ATOM   13687 O O      . TYR B 1 412 ? 1.272   22.523  -23.362 1.00 13.70  ? 412 TYR B O      1 
ATOM   13688 C CB     . TYR B 1 412 ? -0.421  22.847  -26.304 1.00 13.12  ? 412 TYR B CB     1 
ATOM   13689 C CG     . TYR B 1 412 ? -1.263  22.137  -27.339 1.00 15.21  ? 412 TYR B CG     1 
ATOM   13690 C CD1    . TYR B 1 412 ? -0.676  21.574  -28.468 1.00 14.47  ? 412 TYR B CD1    1 
ATOM   13691 C CD2    . TYR B 1 412 ? -2.634  21.987  -27.173 1.00 15.66  ? 412 TYR B CD2    1 
ATOM   13692 C CE1    . TYR B 1 412 ? -1.429  20.901  -29.408 1.00 14.03  ? 412 TYR B CE1    1 
ATOM   13693 C CE2    . TYR B 1 412 ? -3.396  21.312  -28.116 1.00 13.84  ? 412 TYR B CE2    1 
ATOM   13694 C CZ     . TYR B 1 412 ? -2.784  20.767  -29.228 1.00 15.97  ? 412 TYR B CZ     1 
ATOM   13695 O OH     . TYR B 1 412 ? -3.520  20.075  -30.166 1.00 17.19  ? 412 TYR B OH     1 
ATOM   13696 H H      . TYR B 1 412 ? -0.830  21.188  -24.226 1.00 17.28  ? 412 TYR B H      1 
ATOM   13697 H HA     . TYR B 1 412 ? 1.059   21.437  -26.195 1.00 15.03  ? 412 TYR B HA     1 
ATOM   13698 H HB2    . TYR B 1 412 ? -1.018  23.283  -25.676 1.00 15.75  ? 412 TYR B HB2    1 
ATOM   13699 H HB3    . TYR B 1 412 ? 0.126   23.506  -26.759 1.00 15.75  ? 412 TYR B HB3    1 
ATOM   13700 H HD1    . TYR B 1 412 ? 0.242   21.656  -28.593 1.00 17.36  ? 412 TYR B HD1    1 
ATOM   13701 H HD2    . TYR B 1 412 ? -3.047  22.348  -26.422 1.00 18.80  ? 412 TYR B HD2    1 
ATOM   13702 H HE1    . TYR B 1 412 ? -1.019  20.531  -30.156 1.00 16.84  ? 412 TYR B HE1    1 
ATOM   13703 H HE2    . TYR B 1 412 ? -4.313  21.217  -27.994 1.00 16.60  ? 412 TYR B HE2    1 
ATOM   13704 H HH     . TYR B 1 412 ? -4.322  20.027  -29.922 1.00 20.63  ? 412 TYR B HH     1 
ATOM   13705 N N      . THR B 1 413 ? 2.326   23.402  -25.147 1.00 16.27  ? 413 THR B N      1 
ATOM   13706 C CA     . THR B 1 413 ? 3.334   24.120  -24.383 1.00 14.95  ? 413 THR B CA     1 
ATOM   13707 C C      . THR B 1 413 ? 3.139   25.633  -24.556 1.00 16.94  ? 413 THR B C      1 
ATOM   13708 O O      . THR B 1 413 ? 2.304   26.066  -25.353 1.00 15.50  ? 413 THR B O      1 
ATOM   13709 C CB     . THR B 1 413 ? 4.740   23.747  -24.845 1.00 20.46  ? 413 THR B CB     1 
ATOM   13710 O OG1    . THR B 1 413 ? 5.009   24.394  -26.096 1.00 20.04  ? 413 THR B OG1    1 
ATOM   13711 C CG2    . THR B 1 413 ? 4.875   22.234  -25.005 1.00 18.04  ? 413 THR B CG2    1 
ATOM   13712 H H      . THR B 1 413 ? 2.381   23.537  -25.992 1.00 19.52  ? 413 THR B H      1 
ATOM   13713 H HA     . THR B 1 413 ? 3.257   23.907  -23.440 1.00 17.94  ? 413 THR B HA     1 
ATOM   13714 H HB     . THR B 1 413 ? 5.385   24.042  -24.185 1.00 24.55  ? 413 THR B HB     1 
ATOM   13715 H HG1    . THR B 1 413 ? 4.451   24.147  -26.673 1.00 24.05  ? 413 THR B HG1    1 
ATOM   13716 H HG21   . THR B 1 413 ? 5.805   21.998  -25.148 1.00 21.65  ? 413 THR B HG21   1 
ATOM   13717 H HG22   . THR B 1 413 ? 4.556   21.787  -24.206 1.00 21.65  ? 413 THR B HG22   1 
ATOM   13718 H HG23   . THR B 1 413 ? 4.353   21.931  -25.765 1.00 21.65  ? 413 THR B HG23   1 
ATOM   13719 N N      . TYR B 1 414 ? 3.924   26.433  -23.835 1.00 16.10  ? 414 TYR B N      1 
ATOM   13720 C CA     . TYR B 1 414 ? 3.894   27.885  -24.033 1.00 17.85  ? 414 TYR B CA     1 
ATOM   13721 C C      . TYR B 1 414 ? 4.350   28.250  -25.450 1.00 17.67  ? 414 TYR B C      1 
ATOM   13722 O O      . TYR B 1 414 ? 3.946   29.292  -25.985 1.00 16.59  ? 414 TYR B O      1 
ATOM   13723 C CB     . TYR B 1 414 ? 4.785   28.613  -23.020 1.00 19.13  ? 414 TYR B CB     1 
ATOM   13724 C CG     . TYR B 1 414 ? 4.294   28.627  -21.585 1.00 19.04  ? 414 TYR B CG     1 
ATOM   13725 C CD1    . TYR B 1 414 ? 3.149   29.327  -21.226 1.00 18.70  ? 414 TYR B CD1    1 
ATOM   13726 C CD2    . TYR B 1 414 ? 5.000   27.973  -20.579 1.00 21.85  ? 414 TYR B CD2    1 
ATOM   13727 C CE1    . TYR B 1 414 ? 2.705   29.363  -19.910 1.00 18.92  ? 414 TYR B CE1    1 
ATOM   13728 C CE2    . TYR B 1 414 ? 4.565   28.007  -19.256 1.00 20.26  ? 414 TYR B CE2    1 
ATOM   13729 C CZ     . TYR B 1 414 ? 3.415   28.702  -18.928 1.00 18.72  ? 414 TYR B CZ     1 
ATOM   13730 O OH     . TYR B 1 414 ? 2.972   28.744  -17.620 1.00 18.70  ? 414 TYR B OH     1 
ATOM   13731 H H      . TYR B 1 414 ? 4.476   26.166  -23.232 1.00 19.32  ? 414 TYR B H      1 
ATOM   13732 H HA     . TYR B 1 414 ? 2.985   28.202  -23.917 1.00 21.42  ? 414 TYR B HA     1 
ATOM   13733 H HB2    . TYR B 1 414 ? 5.657   28.189  -23.022 1.00 22.95  ? 414 TYR B HB2    1 
ATOM   13734 H HB3    . TYR B 1 414 ? 4.876   29.536  -23.303 1.00 22.95  ? 414 TYR B HB3    1 
ATOM   13735 H HD1    . TYR B 1 414 ? 2.666   29.776  -21.882 1.00 22.44  ? 414 TYR B HD1    1 
ATOM   13736 H HD2    . TYR B 1 414 ? 5.775   27.506  -20.794 1.00 26.22  ? 414 TYR B HD2    1 
ATOM   13737 H HE1    . TYR B 1 414 ? 1.933   29.833  -19.691 1.00 22.71  ? 414 TYR B HE1    1 
ATOM   13738 H HE2    . TYR B 1 414 ? 5.044   27.560  -18.596 1.00 24.31  ? 414 TYR B HE2    1 
ATOM   13739 H HH     . TYR B 1 414 ? 3.492   28.306  -17.126 1.00 22.44  ? 414 TYR B HH     1 
ATOM   13740 N N      . ALA B 1 415 ? 5.209   27.420  -26.047 1.00 16.43  ? 415 ALA B N      1 
ATOM   13741 C CA     . ALA B 1 415 ? 5.689   27.686  -27.408 1.00 17.23  ? 415 ALA B CA     1 
ATOM   13742 C C      . ALA B 1 415 ? 4.548   27.544  -28.403 1.00 20.57  ? 415 ALA B C      1 
ATOM   13743 O O      . ALA B 1 415 ? 4.473   28.287  -29.377 1.00 18.73  ? 415 ALA B O      1 
ATOM   13744 C CB     . ALA B 1 415 ? 6.830   26.753  -27.788 1.00 18.24  ? 415 ALA B CB     1 
ATOM   13745 H H      . ALA B 1 415 ? 5.527   26.704  -25.692 1.00 19.72  ? 415 ALA B H      1 
ATOM   13746 H HA     . ALA B 1 415 ? 6.018   28.597  -27.455 1.00 20.68  ? 415 ALA B HA     1 
ATOM   13747 H HB1    . ALA B 1 415 ? 7.122   26.963  -28.689 1.00 21.89  ? 415 ALA B HB1    1 
ATOM   13748 H HB2    . ALA B 1 415 ? 7.562   26.880  -27.164 1.00 21.89  ? 415 ALA B HB2    1 
ATOM   13749 H HB3    . ALA B 1 415 ? 6.515   25.837  -27.747 1.00 21.89  ? 415 ALA B HB3    1 
ATOM   13750 N N      . HIS B 1 416 ? 3.681   26.560  -28.172 1.00 17.19  ? 416 HIS B N      1 
ATOM   13751 C CA     . HIS B 1 416 ? 2.459   26.430  -28.950 1.00 16.84  ? 416 HIS B CA     1 
ATOM   13752 C C      . HIS B 1 416 ? 1.544   27.633  -28.717 1.00 15.61  ? 416 HIS B C      1 
ATOM   13753 O O      . HIS B 1 416 ? 0.958   28.157  -29.658 1.00 17.42  ? 416 HIS B O      1 
ATOM   13754 C CB     . HIS B 1 416 ? 1.727   25.136  -28.601 1.00 17.05  ? 416 HIS B CB     1 
ATOM   13755 C CG     . HIS B 1 416 ? 2.469   23.899  -28.999 1.00 15.88  ? 416 HIS B CG     1 
ATOM   13756 N ND1    . HIS B 1 416 ? 2.710   22.865  -28.124 1.00 17.12  ? 416 HIS B ND1    1 
ATOM   13757 C CD2    . HIS B 1 416 ? 3.038   23.531  -30.175 1.00 17.11  ? 416 HIS B CD2    1 
ATOM   13758 C CE1    . HIS B 1 416 ? 3.384   21.911  -28.735 1.00 18.42  ? 416 HIS B CE1    1 
ATOM   13759 N NE2    . HIS B 1 416 ? 3.600   22.292  -29.984 1.00 17.58  ? 416 HIS B NE2    1 
ATOM   13760 H H      . HIS B 1 416 ? 3.780   25.955  -27.569 1.00 20.62  ? 416 HIS B H      1 
ATOM   13761 H HA     . HIS B 1 416 ? 2.685   26.402  -29.893 1.00 20.21  ? 416 HIS B HA     1 
ATOM   13762 H HB2    . HIS B 1 416 ? 1.589   25.103  -27.642 1.00 20.46  ? 416 HIS B HB2    1 
ATOM   13763 H HB3    . HIS B 1 416 ? 0.871   25.128  -29.057 1.00 20.46  ? 416 HIS B HB3    1 
ATOM   13764 H HD2    . HIS B 1 416 ? 3.045   24.025  -30.963 1.00 20.53  ? 416 HIS B HD2    1 
ATOM   13765 H HE1    . HIS B 1 416 ? 3.663   21.110  -28.353 1.00 22.11  ? 416 HIS B HE1    1 
ATOM   13766 H HE2    . HIS B 1 416 ? 4.020   21.836  -30.580 1.00 21.10  ? 416 HIS B HE2    1 
ATOM   13767 N N      . MET B 1 417 ? 1.430   28.089  -27.472 1.00 16.66  ? 417 MET B N      1 
ATOM   13768 C CA     . MET B 1 417 ? 0.619   29.273  -27.202 1.00 17.42  ? 417 MET B CA     1 
ATOM   13769 C C      . MET B 1 417 ? 1.193   30.484  -27.947 1.00 18.51  ? 417 MET B C      1 
ATOM   13770 O O      . MET B 1 417 ? 0.446   31.289  -28.500 1.00 16.59  ? 417 MET B O      1 
ATOM   13771 C CB     . MET B 1 417 ? 0.545   29.574  -25.702 1.00 17.93  ? 417 MET B CB     1 
ATOM   13772 C CG     . MET B 1 417 ? -0.128  28.480  -24.853 1.00 18.87  ? 417 MET B CG     1 
ATOM   13773 S SD     . MET B 1 417 ? -1.821  28.088  -25.333 1.00 18.83  ? 417 MET B SD     1 
ATOM   13774 C CE     . MET B 1 417 ? -1.568  26.568  -26.263 1.00 24.49  ? 417 MET B CE     1 
ATOM   13775 H H      . MET B 1 417 ? 1.803   27.740  -26.780 1.00 19.99  ? 417 MET B H      1 
ATOM   13776 H HA     . MET B 1 417 ? -0.284  29.112  -27.518 1.00 20.90  ? 417 MET B HA     1 
ATOM   13777 H HB2    . MET B 1 417 ? 1.447   29.692  -25.365 1.00 21.51  ? 417 MET B HB2    1 
ATOM   13778 H HB3    . MET B 1 417 ? 0.041   30.393  -25.576 1.00 21.51  ? 417 MET B HB3    1 
ATOM   13779 H HG2    . MET B 1 417 ? 0.393   27.666  -24.927 1.00 22.65  ? 417 MET B HG2    1 
ATOM   13780 H HG3    . MET B 1 417 ? -0.146  28.773  -23.928 1.00 22.65  ? 417 MET B HG3    1 
ATOM   13781 H HE1    . MET B 1 417 ? -2.426  26.248  -26.583 1.00 29.39  ? 417 MET B HE1    1 
ATOM   13782 H HE2    . MET B 1 417 ? -0.982  26.751  -27.014 1.00 29.39  ? 417 MET B HE2    1 
ATOM   13783 H HE3    . MET B 1 417 ? -1.164  25.906  -25.681 1.00 29.39  ? 417 MET B HE3    1 
ATOM   13784 N N      . ASP B 1 418 ? 2.518   30.601  -27.967 1.00 18.76  ? 418 ASP B N      1 
ATOM   13785 C CA     . ASP B 1 418 ? 3.177   31.688  -28.700 1.00 19.48  ? 418 ASP B CA     1 
ATOM   13786 C C      . ASP B 1 418 ? 2.865   31.622  -30.198 1.00 24.01  ? 418 ASP B C      1 
ATOM   13787 O O      . ASP B 1 418 ? 2.615   32.646  -30.832 1.00 21.06  ? 418 ASP B O      1 
ATOM   13788 C CB     . ASP B 1 418 ? 4.693   31.649  -28.488 1.00 20.59  ? 418 ASP B CB     1 
ATOM   13789 C CG     . ASP B 1 418 ? 5.127   32.277  -27.164 1.00 25.56  ? 418 ASP B CG     1 
ATOM   13790 O OD1    . ASP B 1 418 ? 4.383   33.098  -26.595 1.00 27.78  ? 418 ASP B OD1    1 
ATOM   13791 O OD2    . ASP B 1 418 ? 6.235   31.953  -26.700 1.00 29.67  ? 418 ASP B OD2    1 
ATOM   13792 H H      . ASP B 1 418 ? 3.060   30.067  -27.566 1.00 22.52  ? 418 ASP B H      1 
ATOM   13793 H HA     . ASP B 1 418 ? 2.842   32.536  -28.372 1.00 23.38  ? 418 ASP B HA     1 
ATOM   13794 H HB2    . ASP B 1 418 ? 4.988   30.725  -28.492 1.00 24.70  ? 418 ASP B HB2    1 
ATOM   13795 H HB3    . ASP B 1 418 ? 5.124   32.137  -29.206 1.00 24.70  ? 418 ASP B HB3    1 
ATOM   13796 N N      . LEU B 1 419 ? 2.879   30.414  -30.755 1.00 19.25  ? 419 LEU B N      1 
ATOM   13797 C CA     . LEU B 1 419 ? 2.604   30.217  -32.174 1.00 22.43  ? 419 LEU B CA     1 
ATOM   13798 C C      . LEU B 1 419 ? 1.189   30.698  -32.514 1.00 18.42  ? 419 LEU B C      1 
ATOM   13799 O O      . LEU B 1 419 ? 0.978   31.395  -33.503 1.00 20.41  ? 419 LEU B O      1 
ATOM   13800 C CB     . LEU B 1 419 ? 2.786   28.737  -32.539 1.00 22.37  ? 419 LEU B CB     1 
ATOM   13801 C CG     . LEU B 1 419 ? 2.577   28.335  -33.996 1.00 30.18  ? 419 LEU B CG     1 
ATOM   13802 C CD1    . LEU B 1 419 ? 3.633   27.332  -34.425 1.00 38.19  ? 419 LEU B CD1    1 
ATOM   13803 C CD2    . LEU B 1 419 ? 1.197   27.746  -34.159 1.00 29.24  ? 419 LEU B CD2    1 
ATOM   13804 H H      . LEU B 1 419 ? 3.047   29.687  -30.328 1.00 23.10  ? 419 LEU B H      1 
ATOM   13805 H HA     . LEU B 1 419 ? 3.234   30.737  -32.696 1.00 26.91  ? 419 LEU B HA     1 
ATOM   13806 H HB2    . LEU B 1 419 ? 3.691   28.480  -32.302 1.00 26.84  ? 419 LEU B HB2    1 
ATOM   13807 H HB3    . LEU B 1 419 ? 2.161   28.220  -32.008 1.00 26.84  ? 419 LEU B HB3    1 
ATOM   13808 H HG     . LEU B 1 419 ? 2.647   29.119  -34.563 1.00 36.21  ? 419 LEU B HG     1 
ATOM   13809 H HD11   . LEU B 1 419 ? 3.462   27.067  -35.342 1.00 45.83  ? 419 LEU B HD11   1 
ATOM   13810 H HD12   . LEU B 1 419 ? 4.508   27.746  -34.358 1.00 45.83  ? 419 LEU B HD12   1 
ATOM   13811 H HD13   . LEU B 1 419 ? 3.587   26.557  -33.843 1.00 45.83  ? 419 LEU B HD13   1 
ATOM   13812 H HD21   . LEU B 1 419 ? 1.081   27.469  -35.081 1.00 35.08  ? 419 LEU B HD21   1 
ATOM   13813 H HD22   . LEU B 1 419 ? 1.108   26.979  -33.571 1.00 35.08  ? 419 LEU B HD22   1 
ATOM   13814 H HD23   . LEU B 1 419 ? 0.536   28.418  -33.929 1.00 35.08  ? 419 LEU B HD23   1 
ATOM   13815 N N      . VAL B 1 420 ? 0.232   30.318  -31.678 1.00 18.00  ? 420 VAL B N      1 
ATOM   13816 C CA     . VAL B 1 420 ? -1.155  30.740  -31.809 1.00 18.84  ? 420 VAL B CA     1 
ATOM   13817 C C      . VAL B 1 420 ? -1.277  32.265  -31.710 1.00 20.01  ? 420 VAL B C      1 
ATOM   13818 O O      . VAL B 1 420 ? -1.865  32.918  -32.574 1.00 19.26  ? 420 VAL B O      1 
ATOM   13819 C CB     . VAL B 1 420 ? -2.037  30.083  -30.709 1.00 20.93  ? 420 VAL B CB     1 
ATOM   13820 C CG1    . VAL B 1 420 ? -3.456  30.575  -30.784 1.00 18.89  ? 420 VAL B CG1    1 
ATOM   13821 C CG2    . VAL B 1 420 ? -2.001  28.546  -30.825 1.00 21.10  ? 420 VAL B CG2    1 
ATOM   13822 H H      . VAL B 1 420 ? 0.367   29.800  -31.005 1.00 21.60  ? 420 VAL B H      1 
ATOM   13823 H HA     . VAL B 1 420 ? -1.493  30.464  -32.675 1.00 22.60  ? 420 VAL B HA     1 
ATOM   13824 H HB     . VAL B 1 420 ? -1.684  30.324  -29.838 1.00 25.12  ? 420 VAL B HB     1 
ATOM   13825 H HG11   . VAL B 1 420 ? -4.023  29.975  -30.274 1.00 22.67  ? 420 VAL B HG11   1 
ATOM   13826 H HG12   . VAL B 1 420 ? -3.504  31.469  -30.412 1.00 22.67  ? 420 VAL B HG12   1 
ATOM   13827 H HG13   . VAL B 1 420 ? -3.738  30.585  -31.712 1.00 22.67  ? 420 VAL B HG13   1 
ATOM   13828 H HG21   . VAL B 1 420 ? -2.285  28.161  -29.982 1.00 25.32  ? 420 VAL B HG21   1 
ATOM   13829 H HG22   . VAL B 1 420 ? -2.603  28.271  -31.533 1.00 25.32  ? 420 VAL B HG22   1 
ATOM   13830 H HG23   . VAL B 1 420 ? -1.099  28.259  -31.031 1.00 25.32  ? 420 VAL B HG23   1 
ATOM   13831 N N      . ALA B 1 421 ? -0.733  32.824  -30.637 1.00 15.59  ? 421 ALA B N      1 
ATOM   13832 C CA     . ALA B 1 421 ? -0.818  34.259  -30.400 1.00 19.93  ? 421 ALA B CA     1 
ATOM   13833 C C      . ALA B 1 421 ? -0.174  35.042  -31.540 1.00 18.10  ? 421 ALA B C      1 
ATOM   13834 O O      . ALA B 1 421 ? -0.755  36.010  -32.037 1.00 19.28  ? 421 ALA B O      1 
ATOM   13835 C CB     . ALA B 1 421 ? -0.161  34.613  -29.086 1.00 20.89  ? 421 ALA B CB     1 
ATOM   13836 H H      . ALA B 1 421 ? -0.307  32.392  -30.028 1.00 18.71  ? 421 ALA B H      1 
ATOM   13837 H HA     . ALA B 1 421 ? -1.752  34.517  -30.348 1.00 23.92  ? 421 ALA B HA     1 
ATOM   13838 H HB1    . ALA B 1 421 ? -0.228  35.571  -28.948 1.00 25.06  ? 421 ALA B HB1    1 
ATOM   13839 H HB2    . ALA B 1 421 ? -0.615  34.142  -28.370 1.00 25.06  ? 421 ALA B HB2    1 
ATOM   13840 H HB3    . ALA B 1 421 ? 0.771   34.348  -29.118 1.00 25.06  ? 421 ALA B HB3    1 
ATOM   13841 N N      . ASP B 1 422 ? 1.022   34.625  -31.949 1.00 19.48  ? 422 ASP B N      1 
ATOM   13842 C CA     . ASP B 1 422 ? 1.771   35.350  -32.971 1.00 20.75  ? 422 ASP B CA     1 
ATOM   13843 C C      . ASP B 1 422 ? 1.025   35.366  -34.293 1.00 22.25  ? 422 ASP B C      1 
ATOM   13844 O O      . ASP B 1 422 ? 1.021   36.379  -34.998 1.00 22.55  ? 422 ASP B O      1 
ATOM   13845 C CB     . ASP B 1 422 ? 3.155   34.738  -33.176 1.00 22.83  ? 422 ASP B CB     1 
ATOM   13846 C CG     . ASP B 1 422 ? 4.081   34.976  -32.000 1.00 28.39  ? 422 ASP B CG     1 
ATOM   13847 O OD1    . ASP B 1 422 ? 3.731   35.782  -31.107 1.00 29.99  ? 422 ASP B OD1    1 
ATOM   13848 O OD2    . ASP B 1 422 ? 5.170   34.369  -31.991 1.00 32.74  ? 422 ASP B OD2    1 
ATOM   13849 H H      . ASP B 1 422 ? 1.422   33.925  -31.650 1.00 23.38  ? 422 ASP B H      1 
ATOM   13850 H HA     . ASP B 1 422 ? 1.885   36.270  -32.687 1.00 24.90  ? 422 ASP B HA     1 
ATOM   13851 H HB2    . ASP B 1 422 ? 3.062   33.780  -33.296 1.00 27.39  ? 422 ASP B HB2    1 
ATOM   13852 H HB3    . ASP B 1 422 ? 3.562   35.133  -33.963 1.00 27.39  ? 422 ASP B HB3    1 
ATOM   13853 N N      . GLY B 1 423 ? 0.385   34.250  -34.626 1.00 19.23  ? 423 GLY B N      1 
ATOM   13854 C CA     . GLY B 1 423 ? -0.362  34.170  -35.867 1.00 19.93  ? 423 GLY B CA     1 
ATOM   13855 C C      . GLY B 1 423 ? -1.574  35.080  -35.819 1.00 20.44  ? 423 GLY B C      1 
ATOM   13856 O O      . GLY B 1 423 ? -1.861  35.804  -36.772 1.00 19.09  ? 423 GLY B O      1 
ATOM   13857 H H      . GLY B 1 423 ? 0.370   33.532  -34.153 1.00 23.07  ? 423 GLY B H      1 
ATOM   13858 H HA2    . GLY B 1 423 ? 0.202   34.438  -36.609 1.00 23.92  ? 423 GLY B HA2    1 
ATOM   13859 H HA3    . GLY B 1 423 ? -0.660  33.259  -36.013 1.00 23.92  ? 423 GLY B HA3    1 
ATOM   13860 N N      . ILE B 1 424 ? -2.288  35.053  -34.699 1.00 16.09  ? 424 ILE B N      1 
ATOM   13861 C CA     . ILE B 1 424 ? -3.481  35.881  -34.546 1.00 18.10  ? 424 ILE B CA     1 
ATOM   13862 C C      . ILE B 1 424 ? -3.118  37.376  -34.563 1.00 20.82  ? 424 ILE B C      1 
ATOM   13863 O O      . ILE B 1 424 ? -3.827  38.196  -35.159 1.00 19.00  ? 424 ILE B O      1 
ATOM   13864 C CB     . ILE B 1 424 ? -4.236  35.530  -33.249 1.00 18.90  ? 424 ILE B CB     1 
ATOM   13865 C CG1    . ILE B 1 424 ? -4.840  34.125  -33.360 1.00 17.35  ? 424 ILE B CG1    1 
ATOM   13866 C CG2    . ILE B 1 424 ? -5.369  36.538  -32.980 1.00 19.83  ? 424 ILE B CG2    1 
ATOM   13867 C CD1    . ILE B 1 424 ? -5.334  33.528  -32.041 1.00 19.93  ? 424 ILE B CD1    1 
ATOM   13868 H H      . ILE B 1 424 ? -2.105  34.566  -34.014 1.00 19.31  ? 424 ILE B H      1 
ATOM   13869 H HA     . ILE B 1 424 ? -4.077  35.712  -35.292 1.00 21.72  ? 424 ILE B HA     1 
ATOM   13870 H HB     . ILE B 1 424 ? -3.613  35.549  -32.506 1.00 22.68  ? 424 ILE B HB     1 
ATOM   13871 H HG12   . ILE B 1 424 ? -5.597  34.162  -33.966 1.00 20.81  ? 424 ILE B HG12   1 
ATOM   13872 H HG13   . ILE B 1 424 ? -4.167  33.526  -33.718 1.00 20.81  ? 424 ILE B HG13   1 
ATOM   13873 H HG21   . ILE B 1 424 ? -5.971  36.171  -32.315 1.00 23.79  ? 424 ILE B HG21   1 
ATOM   13874 H HG22   . ILE B 1 424 ? -4.987  37.367  -32.652 1.00 23.79  ? 424 ILE B HG22   1 
ATOM   13875 H HG23   . ILE B 1 424 ? -5.851  36.698  -33.807 1.00 23.79  ? 424 ILE B HG23   1 
ATOM   13876 H HD11   . ILE B 1 424 ? -5.588  32.604  -32.190 1.00 23.92  ? 424 ILE B HD11   1 
ATOM   13877 H HD12   . ILE B 1 424 ? -4.618  33.573  -31.388 1.00 23.92  ? 424 ILE B HD12   1 
ATOM   13878 H HD13   . ILE B 1 424 ? -6.099  34.035  -31.729 1.00 23.92  ? 424 ILE B HD13   1 
ATOM   13879 N N      . ILE B 1 425 ? -2.008  37.724  -33.926 1.00 17.73  ? 425 ILE B N      1 
ATOM   13880 C CA     . ILE B 1 425 ? -1.584  39.120  -33.843 1.00 19.73  ? 425 ILE B CA     1 
ATOM   13881 C C      . ILE B 1 425 ? -1.164  39.628  -35.224 1.00 23.16  ? 425 ILE B C      1 
ATOM   13882 O O      . ILE B 1 425 ? -1.475  40.763  -35.588 1.00 23.40  ? 425 ILE B O      1 
ATOM   13883 C CB     . ILE B 1 425 ? -0.447  39.290  -32.820 1.00 20.06  ? 425 ILE B CB     1 
ATOM   13884 C CG1    . ILE B 1 425 ? -1.008  39.124  -31.401 1.00 22.01  ? 425 ILE B CG1    1 
ATOM   13885 C CG2    . ILE B 1 425 ? 0.231   40.675  -32.946 1.00 24.50  ? 425 ILE B CG2    1 
ATOM   13886 C CD1    . ILE B 1 425 ? 0.052   38.902  -30.340 1.00 23.61  ? 425 ILE B CD1    1 
ATOM   13887 H H      . ILE B 1 425 ? -1.480  37.172  -33.532 1.00 21.28  ? 425 ILE B H      1 
ATOM   13888 H HA     . ILE B 1 425 ? -2.334  39.658  -33.544 1.00 23.67  ? 425 ILE B HA     1 
ATOM   13889 H HB     . ILE B 1 425 ? 0.218   38.601  -32.975 1.00 24.07  ? 425 ILE B HB     1 
ATOM   13890 H HG12   . ILE B 1 425 ? -1.498  39.927  -31.165 1.00 26.41  ? 425 ILE B HG12   1 
ATOM   13891 H HG13   . ILE B 1 425 ? -1.605  38.360  -31.388 1.00 26.41  ? 425 ILE B HG13   1 
ATOM   13892 H HG21   . ILE B 1 425 ? 0.764   40.841  -32.153 1.00 29.40  ? 425 ILE B HG21   1 
ATOM   13893 H HG22   . ILE B 1 425 ? 0.802   40.680  -33.730 1.00 29.40  ? 425 ILE B HG22   1 
ATOM   13894 H HG23   . ILE B 1 425 ? -0.455  41.355  -33.030 1.00 29.40  ? 425 ILE B HG23   1 
ATOM   13895 H HD11   . ILE B 1 425 ? -0.383  38.670  -29.504 1.00 28.34  ? 425 ILE B HD11   1 
ATOM   13896 H HD12   . ILE B 1 425 ? 0.633   38.178  -30.622 1.00 28.34  ? 425 ILE B HD12   1 
ATOM   13897 H HD13   . ILE B 1 425 ? 0.567   39.716  -30.230 1.00 28.34  ? 425 ILE B HD13   1 
ATOM   13898 N N      . LYS B 1 426 ? -0.473  38.785  -35.991 1.00 20.56  ? 426 LYS B N      1 
ATOM   13899 C CA     . LYS B 1 426 ? -0.134  39.108  -37.375 1.00 25.72  ? 426 LYS B CA     1 
ATOM   13900 C C      . LYS B 1 426 ? -1.395  39.361  -38.212 1.00 26.97  ? 426 LYS B C      1 
ATOM   13901 O O      . LYS B 1 426 ? -1.446  40.309  -38.999 1.00 24.34  ? 426 LYS B O      1 
ATOM   13902 C CB     . LYS B 1 426 ? 0.695   37.980  -38.000 1.00 27.33  ? 426 LYS B CB     1 
ATOM   13903 C CG     . LYS B 1 426 ? 1.189   38.271  -39.402 1.00 34.17  ? 426 LYS B CG     1 
ATOM   13904 C CD     . LYS B 1 426 ? 2.077   37.141  -39.900 1.00 39.85  ? 426 LYS B CD     1 
ATOM   13905 C CE     . LYS B 1 426 ? 2.603   37.418  -41.304 1.00 50.25  ? 426 LYS B CE     1 
ATOM   13906 N NZ     . LYS B 1 426 ? 3.437   36.301  -41.811 1.00 55.01  ? 426 LYS B NZ     1 
ATOM   13907 H H      . LYS B 1 426 ? -0.188  38.016  -35.731 1.00 24.67  ? 426 LYS B H      1 
ATOM   13908 H HA     . LYS B 1 426 ? 0.402   39.917  -37.388 1.00 30.86  ? 426 LYS B HA     1 
ATOM   13909 H HB2    . LYS B 1 426 ? 1.472   37.819  -37.441 1.00 32.80  ? 426 LYS B HB2    1 
ATOM   13910 H HB3    . LYS B 1 426 ? 0.149   37.179  -38.040 1.00 32.80  ? 426 LYS B HB3    1 
ATOM   13911 H HG2    . LYS B 1 426 ? 0.432   38.352  -40.003 1.00 41.00  ? 426 LYS B HG2    1 
ATOM   13912 H HG3    . LYS B 1 426 ? 1.708   39.091  -39.398 1.00 41.00  ? 426 LYS B HG3    1 
ATOM   13913 H HD2    . LYS B 1 426 ? 2.837   37.045  -39.304 1.00 47.82  ? 426 LYS B HD2    1 
ATOM   13914 H HD3    . LYS B 1 426 ? 1.564   36.319  -39.925 1.00 47.82  ? 426 LYS B HD3    1 
ATOM   13915 H HE2    . LYS B 1 426 ? 1.853   37.535  -41.908 1.00 60.30  ? 426 LYS B HE2    1 
ATOM   13916 H HE3    . LYS B 1 426 ? 3.148   38.220  -41.288 1.00 60.30  ? 426 LYS B HE3    1 
ATOM   13917 H HZ1    . LYS B 1 426 ? 3.730   36.488  -42.630 1.00 66.01  ? 426 LYS B HZ1    1 
ATOM   13918 H HZ2    . LYS B 1 426 ? 4.136   36.176  -41.275 1.00 66.01  ? 426 LYS B HZ2    1 
ATOM   13919 H HZ3    . LYS B 1 426 ? 2.957   35.552  -41.840 1.00 66.01  ? 426 LYS B HZ3    1 
ATOM   13920 N N      . LEU B 1 427 ? -2.403  38.505  -38.049 1.00 22.77  ? 427 LEU B N      1 
ATOM   13921 C CA     . LEU B 1 427 ? -3.676  38.678  -38.750 1.00 23.46  ? 427 LEU B CA     1 
ATOM   13922 C C      . LEU B 1 427 ? -4.351  39.976  -38.326 1.00 23.97  ? 427 LEU B C      1 
ATOM   13923 O O      . LEU B 1 427 ? -4.927  40.701  -39.153 1.00 22.89  ? 427 LEU B O      1 
ATOM   13924 C CB     . LEU B 1 427 ? -4.615  37.495  -38.482 1.00 19.70  ? 427 LEU B CB     1 
ATOM   13925 C CG     . LEU B 1 427 ? -4.255  36.194  -39.209 1.00 22.36  ? 427 LEU B CG     1 
ATOM   13926 C CD1    . LEU B 1 427 ? -5.105  35.032  -38.684 1.00 18.92  ? 427 LEU B CD1    1 
ATOM   13927 C CD2    . LEU B 1 427 ? -4.439  36.352  -40.708 1.00 21.13  ? 427 LEU B CD2    1 
ATOM   13928 H H      . LEU B 1 427 ? -2.376  37.814  -37.537 1.00 27.32  ? 427 LEU B H      1 
ATOM   13929 H HA     . LEU B 1 427 ? -3.509  38.726  -39.704 1.00 28.15  ? 427 LEU B HA     1 
ATOM   13930 H HB2    . LEU B 1 427 ? -4.610  37.308  -37.530 1.00 23.64  ? 427 LEU B HB2    1 
ATOM   13931 H HB3    . LEU B 1 427 ? -5.511  37.745  -38.758 1.00 23.64  ? 427 LEU B HB3    1 
ATOM   13932 H HG     . LEU B 1 427 ? -3.323  35.985  -39.041 1.00 26.83  ? 427 LEU B HG     1 
ATOM   13933 H HD11   . LEU B 1 427 ? -4.858  34.222  -39.157 1.00 22.71  ? 427 LEU B HD11   1 
ATOM   13934 H HD12   . LEU B 1 427 ? -4.940  34.924  -37.734 1.00 22.71  ? 427 LEU B HD12   1 
ATOM   13935 H HD13   . LEU B 1 427 ? -6.042  35.232  -38.837 1.00 22.71  ? 427 LEU B HD13   1 
ATOM   13936 H HD21   . LEU B 1 427 ? -4.358  35.482  -41.129 1.00 25.35  ? 427 LEU B HD21   1 
ATOM   13937 H HD22   . LEU B 1 427 ? -5.319  36.722  -40.880 1.00 25.35  ? 427 LEU B HD22   1 
ATOM   13938 H HD23   . LEU B 1 427 ? -3.756  36.949  -41.050 1.00 25.35  ? 427 LEU B HD23   1 
ATOM   13939 N N      . PHE B 1 428 ? -4.287  40.266  -37.032 1.00 19.28  ? 428 PHE B N      1 
ATOM   13940 C CA     . PHE B 1 428 ? -4.921  41.464  -36.492 1.00 23.28  ? 428 PHE B CA     1 
ATOM   13941 C C      . PHE B 1 428 ? -4.298  42.729  -37.064 1.00 24.82  ? 428 PHE B C      1 
ATOM   13942 O O      . PHE B 1 428 ? -4.998  43.703  -37.355 1.00 24.03  ? 428 PHE B O      1 
ATOM   13943 C CB     . PHE B 1 428 ? -4.809  41.481  -34.972 1.00 19.83  ? 428 PHE B CB     1 
ATOM   13944 C CG     . PHE B 1 428 ? -5.568  42.593  -34.321 1.00 21.73  ? 428 PHE B CG     1 
ATOM   13945 C CD1    . PHE B 1 428 ? -6.942  42.663  -34.431 1.00 22.91  ? 428 PHE B CD1    1 
ATOM   13946 C CD2    . PHE B 1 428 ? -4.906  43.556  -33.578 1.00 25.69  ? 428 PHE B CD2    1 
ATOM   13947 C CE1    . PHE B 1 428 ? -7.644  43.682  -33.823 1.00 25.70  ? 428 PHE B CE1    1 
ATOM   13948 C CE2    . PHE B 1 428 ? -5.602  44.569  -32.969 1.00 24.91  ? 428 PHE B CE2    1 
ATOM   13949 C CZ     . PHE B 1 428 ? -6.970  44.633  -33.088 1.00 28.15  ? 428 PHE B CZ     1 
ATOM   13950 H H      . PHE B 1 428 ? -3.883  39.786  -36.444 1.00 23.13  ? 428 PHE B H      1 
ATOM   13951 H HA     . PHE B 1 428 ? -5.862  41.458  -36.727 1.00 27.94  ? 428 PHE B HA     1 
ATOM   13952 H HB2    . PHE B 1 428 ? -5.153  40.644  -34.624 1.00 23.79  ? 428 PHE B HB2    1 
ATOM   13953 H HB3    . PHE B 1 428 ? -3.875  41.578  -34.729 1.00 23.79  ? 428 PHE B HB3    1 
ATOM   13954 H HD1    . PHE B 1 428 ? -7.398  42.020  -34.925 1.00 27.49  ? 428 PHE B HD1    1 
ATOM   13955 H HD2    . PHE B 1 428 ? -3.981  43.516  -33.492 1.00 30.83  ? 428 PHE B HD2    1 
ATOM   13956 H HE1    . PHE B 1 428 ? -8.569  43.724  -33.904 1.00 30.83  ? 428 PHE B HE1    1 
ATOM   13957 H HE2    . PHE B 1 428 ? -5.148  45.213  -32.475 1.00 29.89  ? 428 PHE B HE2    1 
ATOM   13958 H HZ     . PHE B 1 428 ? -7.440  45.323  -32.678 1.00 33.78  ? 428 PHE B HZ     1 
ATOM   13959 N N      . LYS B 1 429 ? -2.981  42.721  -37.216 1.00 20.82  ? 429 LYS B N      1 
ATOM   13960 C CA     . LYS B 1 429 ? -2.284  43.902  -37.713 1.00 28.75  ? 429 LYS B CA     1 
ATOM   13961 C C      . LYS B 1 429 ? -2.681  44.200  -39.157 1.00 31.32  ? 429 LYS B C      1 
ATOM   13962 O O      . LYS B 1 429 ? -2.519  45.325  -39.624 1.00 25.46  ? 429 LYS B O      1 
ATOM   13963 C CB     . LYS B 1 429 ? -0.772  43.718  -37.601 1.00 26.56  ? 429 LYS B CB     1 
ATOM   13964 C CG     . LYS B 1 429 ? -0.242  43.849  -36.169 1.00 35.59  ? 429 LYS B CG     1 
ATOM   13965 C CD     . LYS B 1 429 ? 1.239   43.528  -36.096 1.00 41.12  ? 429 LYS B CD     1 
ATOM   13966 C CE     . LYS B 1 429 ? 1.756   43.587  -34.667 1.00 46.66  ? 429 LYS B CE     1 
ATOM   13967 N NZ     . LYS B 1 429 ? 3.173   43.144  -34.590 1.00 56.41  ? 429 LYS B NZ     1 
ATOM   13968 H H      . LYS B 1 429 ? -2.470  42.052  -37.041 1.00 24.98  ? 429 LYS B H      1 
ATOM   13969 H HA     . LYS B 1 429 ? -2.533  44.667  -37.170 1.00 34.50  ? 429 LYS B HA     1 
ATOM   13970 H HB2    . LYS B 1 429 ? -0.539  42.833  -37.924 1.00 31.88  ? 429 LYS B HB2    1 
ATOM   13971 H HB3    . LYS B 1 429 ? -0.333  44.392  -38.143 1.00 31.88  ? 429 LYS B HB3    1 
ATOM   13972 H HG2    . LYS B 1 429 ? -0.371  44.760  -35.862 1.00 42.71  ? 429 LYS B HG2    1 
ATOM   13973 H HG3    . LYS B 1 429 ? -0.717  43.230  -35.593 1.00 42.71  ? 429 LYS B HG3    1 
ATOM   13974 H HD2    . LYS B 1 429 ? 1.389   42.632  -36.437 1.00 49.35  ? 429 LYS B HD2    1 
ATOM   13975 H HD3    . LYS B 1 429 ? 1.733   44.175  -36.624 1.00 49.35  ? 429 LYS B HD3    1 
ATOM   13976 H HE2    . LYS B 1 429 ? 1.704   44.500  -34.344 1.00 56.00  ? 429 LYS B HE2    1 
ATOM   13977 H HE3    . LYS B 1 429 ? 1.222   43.001  -34.108 1.00 56.00  ? 429 LYS B HE3    1 
ATOM   13978 H HZ1    . LYS B 1 429 ? 3.459   43.185  -33.748 1.00 67.70  ? 429 LYS B HZ1    1 
ATOM   13979 H HZ2    . LYS B 1 429 ? 3.246   42.306  -34.880 1.00 67.70  ? 429 LYS B HZ2    1 
ATOM   13980 H HZ3    . LYS B 1 429 ? 3.684   43.670  -35.095 1.00 67.70  ? 429 LYS B HZ3    1 
ATOM   13981 N N      . HIS B 1 430 ? -3.205  43.188  -39.849 1.00 25.24  ? 430 HIS B N      1 
ATOM   13982 C CA     . HIS B 1 430 ? -3.703  43.337  -41.217 1.00 31.47  ? 430 HIS B CA     1 
ATOM   13983 C C      . HIS B 1 430 ? -5.153  42.893  -41.325 1.00 23.07  ? 430 HIS B C      1 
ATOM   13984 O O      . HIS B 1 430 ? -5.557  42.339  -42.339 1.00 22.01  ? 430 HIS B O      1 
ATOM   13985 C CB     . HIS B 1 430 ? -2.852  42.522  -42.194 1.00 33.62  ? 430 HIS B CB     1 
ATOM   13986 C CG     . HIS B 1 430 ? -1.412  42.920  -42.210 1.00 39.90  ? 430 HIS B CG     1 
ATOM   13987 N ND1    . HIS B 1 430 ? -0.472  42.349  -41.378 1.00 47.52  ? 430 HIS B ND1    1 
ATOM   13988 C CD2    . HIS B 1 430 ? -0.754  43.847  -42.943 1.00 42.41  ? 430 HIS B CD2    1 
ATOM   13989 C CE1    . HIS B 1 430 ? 0.706   42.903  -41.606 1.00 46.44  ? 430 HIS B CE1    1 
ATOM   13990 N NE2    . HIS B 1 430 ? 0.562   43.813  -42.552 1.00 45.54  ? 430 HIS B NE2    1 
ATOM   13991 H H      . HIS B 1 430 ? -3.284  42.388  -39.544 1.00 30.28  ? 430 HIS B H      1 
ATOM   13992 H HA     . HIS B 1 430 ? -3.656  44.268  -41.484 1.00 37.77  ? 430 HIS B HA     1 
ATOM   13993 H HB2    . HIS B 1 430 ? -2.900  41.585  -41.946 1.00 40.35  ? 430 HIS B HB2    1 
ATOM   13994 H HB3    . HIS B 1 430 ? -3.198  42.644  -43.092 1.00 40.35  ? 430 HIS B HB3    1 
ATOM   13995 H HD1    . HIS B 1 430 ? -0.627  41.728  -40.803 1.00 57.03  ? 430 HIS B HD1    1 
ATOM   13996 H HD2    . HIS B 1 430 ? -1.122  44.399  -43.594 1.00 50.89  ? 430 HIS B HD2    1 
ATOM   13997 H HE1    . HIS B 1 430 ? 1.501   42.687  -41.175 1.00 55.73  ? 430 HIS B HE1    1 
ATOM   13998 N N      . LYS B 1 431 ? -5.928  43.138  -40.278 1.00 21.41  ? 431 LYS B N      1 
ATOM   13999 C CA     . LYS B 1 431 ? -7.288  42.616  -40.179 1.00 24.96  ? 431 LYS B CA     1 
ATOM   14000 C C      . LYS B 1 431 ? -8.164  42.974  -41.379 1.00 25.98  ? 431 LYS B C      1 
ATOM   14001 O O      . LYS B 1 431 ? -9.033  42.196  -41.762 1.00 22.94  ? 431 LYS B O      1 
ATOM   14002 C CB     . LYS B 1 431 ? -7.946  43.120  -38.893 1.00 24.77  ? 431 LYS B CB     1 
ATOM   14003 C CG     . LYS B 1 431 ? -8.034  44.642  -38.781 1.00 27.96  ? 431 LYS B CG     1 
ATOM   14004 C CD     . LYS B 1 431 ? -8.340  45.058  -37.351 1.00 27.68  ? 431 LYS B CD     1 
ATOM   14005 C CE     . LYS B 1 431 ? -8.536  46.569  -37.227 1.00 30.91  ? 431 LYS B CE     1 
ATOM   14006 N NZ     . LYS B 1 431 ? -8.757  46.943  -35.807 1.00 44.69  ? 431 LYS B NZ     1 
ATOM   14007 H H      . LYS B 1 431 ? -5.687  43.610  -39.601 1.00 25.69  ? 431 LYS B H      1 
ATOM   14008 H HA     . LYS B 1 431 ? -7.244  41.648  -40.127 1.00 29.95  ? 431 LYS B HA     1 
ATOM   14009 H HB2    . LYS B 1 431 ? -8.849  42.769  -38.849 1.00 29.73  ? 431 LYS B HB2    1 
ATOM   14010 H HB3    . LYS B 1 431 ? -7.433  42.798  -38.135 1.00 29.73  ? 431 LYS B HB3    1 
ATOM   14011 H HG2    . LYS B 1 431 ? -7.187  45.037  -39.039 1.00 33.55  ? 431 LYS B HG2    1 
ATOM   14012 H HG3    . LYS B 1 431 ? -8.747  44.967  -39.353 1.00 33.55  ? 431 LYS B HG3    1 
ATOM   14013 H HD2    . LYS B 1 431 ? -9.156  44.623  -37.059 1.00 33.21  ? 431 LYS B HD2    1 
ATOM   14014 H HD3    . LYS B 1 431 ? -7.600  44.801  -36.779 1.00 33.21  ? 431 LYS B HD3    1 
ATOM   14015 H HE2    . LYS B 1 431 ? -7.742  47.026  -37.546 1.00 37.10  ? 431 LYS B HE2    1 
ATOM   14016 H HE3    . LYS B 1 431 ? -9.313  46.838  -37.741 1.00 37.10  ? 431 LYS B HE3    1 
ATOM   14017 H HZ1    . LYS B 1 431 ? -8.871  47.823  -35.739 1.00 53.63  ? 431 LYS B HZ1    1 
ATOM   14018 H HZ2    . LYS B 1 431 ? -9.482  46.532  -35.494 1.00 53.63  ? 431 LYS B HZ2    1 
ATOM   14019 H HZ3    . LYS B 1 431 ? -8.054  46.703  -35.317 1.00 53.63  ? 431 LYS B HZ3    1 
ATOM   14020 N N      . GLU B 1 432 ? -7.922  44.141  -41.974 1.00 25.68  ? 432 GLU B N      1 
ATOM   14021 C CA     . GLU B 1 432 ? -8.740  44.615  -43.089 1.00 30.50  ? 432 GLU B CA     1 
ATOM   14022 C C      . GLU B 1 432 ? -8.661  43.693  -44.307 1.00 31.96  ? 432 GLU B C      1 
ATOM   14023 O O      . GLU B 1 432 ? -9.523  43.751  -45.185 1.00 29.13  ? 432 GLU B O      1 
ATOM   14024 C CB     . GLU B 1 432 ? -8.332  46.043  -43.484 1.00 34.65  ? 432 GLU B CB     1 
ATOM   14025 C CG     . GLU B 1 432 ? -6.918  46.178  -44.066 1.00 38.45  ? 432 GLU B CG     1 
ATOM   14026 C CD     . GLU B 1 432 ? -5.821  46.239  -43.008 1.00 49.75  ? 432 GLU B CD     1 
ATOM   14027 O OE1    . GLU B 1 432 ? -4.635  46.289  -43.409 1.00 44.46  ? 432 GLU B OE1    1 
ATOM   14028 O OE2    . GLU B 1 432 ? -6.137  46.244  -41.790 1.00 37.18  ? 432 GLU B OE2    1 
ATOM   14029 H H      . GLU B 1 432 ? -7.291  44.678  -41.746 1.00 30.81  ? 432 GLU B H      1 
ATOM   14030 H HA     . GLU B 1 432 ? -9.666  44.643  -42.802 1.00 36.61  ? 432 GLU B HA     1 
ATOM   14031 H HB2    . GLU B 1 432 ? -8.952  46.361  -44.159 1.00 41.58  ? 432 GLU B HB2    1 
ATOM   14032 H HB3    . GLU B 1 432 ? -8.391  46.612  -42.701 1.00 41.58  ? 432 GLU B HB3    1 
ATOM   14033 H HG2    . GLU B 1 432 ? -6.731  45.421  -44.642 1.00 46.14  ? 432 GLU B HG2    1 
ATOM   14034 H HG3    . GLU B 1 432 ? -6.873  46.998  -44.582 1.00 46.14  ? 432 GLU B HG3    1 
ATOM   14035 N N      . ASP B 1 433 ? -7.637  42.840  -44.350 1.00 27.82  ? 433 ASP B N      1 
ATOM   14036 C CA     . ASP B 1 433 ? -7.456  41.902  -45.455 1.00 28.80  ? 433 ASP B CA     1 
ATOM   14037 C C      . ASP B 1 433 ? -8.233  40.599  -45.292 1.00 27.23  ? 433 ASP B C      1 
ATOM   14038 O O      . ASP B 1 433 ? -8.211  39.758  -46.188 1.00 26.06  ? 433 ASP B O      1 
ATOM   14039 C CB     . ASP B 1 433 ? -5.974  41.565  -45.626 1.00 29.72  ? 433 ASP B CB     1 
ATOM   14040 C CG     . ASP B 1 433 ? -5.154  42.753  -46.089 1.00 33.40  ? 433 ASP B CG     1 
ATOM   14041 O OD1    . ASP B 1 433 ? -5.743  43.707  -46.636 1.00 41.54  ? 433 ASP B OD1    1 
ATOM   14042 O OD2    . ASP B 1 433 ? -3.920  42.728  -45.910 1.00 33.98  ? 433 ASP B OD2    1 
ATOM   14043 H H      . ASP B 1 433 ? -7.027  42.785  -43.746 1.00 33.38  ? 433 ASP B H      1 
ATOM   14044 H HA     . ASP B 1 433 ? -7.762  42.320  -46.275 1.00 34.56  ? 433 ASP B HA     1 
ATOM   14045 H HB2    . ASP B 1 433 ? -5.617  41.267  -44.775 1.00 35.67  ? 433 ASP B HB2    1 
ATOM   14046 H HB3    . ASP B 1 433 ? -5.883  40.862  -46.288 1.00 35.67  ? 433 ASP B HB3    1 
ATOM   14047 N N      . ILE B 1 434 ? -8.904  40.414  -44.156 1.00 22.46  ? 434 ILE B N      1 
ATOM   14048 C CA     . ILE B 1 434 ? -9.727  39.224  -43.961 1.00 19.81  ? 434 ILE B CA     1 
ATOM   14049 C C      . ILE B 1 434 ? -11.043 39.382  -44.726 1.00 25.13  ? 434 ILE B C      1 
ATOM   14050 O O      . ILE B 1 434 ? -11.794 40.334  -44.519 1.00 21.78  ? 434 ILE B O      1 
ATOM   14051 C CB     . ILE B 1 434 ? -9.988  38.958  -42.461 1.00 20.68  ? 434 ILE B CB     1 
ATOM   14052 C CG1    . ILE B 1 434 ? -8.666  38.640  -41.761 1.00 27.54  ? 434 ILE B CG1    1 
ATOM   14053 C CG2    . ILE B 1 434 ? -10.955 37.809  -42.274 1.00 23.03  ? 434 ILE B CG2    1 
ATOM   14054 C CD1    . ILE B 1 434 ? -8.758  38.612  -40.254 1.00 26.53  ? 434 ILE B CD1    1 
ATOM   14055 H H      . ILE B 1 434 ? -8.900  40.956  -43.489 1.00 26.95  ? 434 ILE B H      1 
ATOM   14056 H HA     . ILE B 1 434 ? -9.262  38.453  -44.321 1.00 23.78  ? 434 ILE B HA     1 
ATOM   14057 H HB     . ILE B 1 434 ? -10.369 39.756  -42.063 1.00 24.81  ? 434 ILE B HB     1 
ATOM   14058 H HG12   . ILE B 1 434 ? -8.360  37.767  -42.055 1.00 33.05  ? 434 ILE B HG12   1 
ATOM   14059 H HG13   . ILE B 1 434 ? -8.013  39.315  -42.003 1.00 33.05  ? 434 ILE B HG13   1 
ATOM   14060 H HG21   . ILE B 1 434 ? -10.973 37.555  -41.339 1.00 27.64  ? 434 ILE B HG21   1 
ATOM   14061 H HG22   . ILE B 1 434 ? -11.841 38.089  -42.552 1.00 27.64  ? 434 ILE B HG22   1 
ATOM   14062 H HG23   . ILE B 1 434 ? -10.660 37.059  -42.813 1.00 27.64  ? 434 ILE B HG23   1 
ATOM   14063 H HD11   . ILE B 1 434 ? -7.861  38.616  -39.884 1.00 31.84  ? 434 ILE B HD11   1 
ATOM   14064 H HD12   . ILE B 1 434 ? -9.243  39.396  -39.954 1.00 31.84  ? 434 ILE B HD12   1 
ATOM   14065 H HD13   . ILE B 1 434 ? -9.226  37.808  -39.979 1.00 31.84  ? 434 ILE B HD13   1 
ATOM   14066 N N      . LYS B 1 435 ? -11.310 38.449  -45.633 1.00 19.22  ? 435 LYS B N      1 
ATOM   14067 C CA     . LYS B 1 435 ? -12.474 38.558  -46.497 1.00 21.41  ? 435 LYS B CA     1 
ATOM   14068 C C      . LYS B 1 435 ? -13.684 37.875  -45.886 1.00 22.47  ? 435 LYS B C      1 
ATOM   14069 O O      . LYS B 1 435 ? -13.566 36.923  -45.107 1.00 21.44  ? 435 LYS B O      1 
ATOM   14070 C CB     . LYS B 1 435 ? -12.182 37.946  -47.874 1.00 23.21  ? 435 LYS B CB     1 
ATOM   14071 C CG     . LYS B 1 435 ? -11.027 38.565  -48.616 1.00 26.69  ? 435 LYS B CG     1 
ATOM   14072 C CD     . LYS B 1 435 ? -10.814 37.861  -49.962 1.00 42.08  ? 435 LYS B CD     1 
ATOM   14073 C CE     . LYS B 1 435 ? -9.579  38.375  -50.691 1.00 60.93  ? 435 LYS B CE     1 
ATOM   14074 N NZ     . LYS B 1 435 ? -9.717  39.791  -51.133 1.00 68.12  ? 435 LYS B NZ     1 
ATOM   14075 H H      . LYS B 1 435 ? -10.833 37.746  -45.767 1.00 23.06  ? 435 LYS B H      1 
ATOM   14076 H HA     . LYS B 1 435 ? -12.692 39.493  -46.631 1.00 25.69  ? 435 LYS B HA     1 
ATOM   14077 H HB2    . LYS B 1 435 ? -11.980 37.005  -47.755 1.00 27.85  ? 435 LYS B HB2    1 
ATOM   14078 H HB3    . LYS B 1 435 ? -12.972 38.042  -48.429 1.00 27.85  ? 435 LYS B HB3    1 
ATOM   14079 H HG2    . LYS B 1 435 ? -11.216 39.501  -48.786 1.00 32.03  ? 435 LYS B HG2    1 
ATOM   14080 H HG3    . LYS B 1 435 ? -10.218 38.472  -48.090 1.00 32.03  ? 435 LYS B HG3    1 
ATOM   14081 H HD2    . LYS B 1 435 ? -10.700 36.910  -49.809 1.00 50.49  ? 435 LYS B HD2    1 
ATOM   14082 H HD3    . LYS B 1 435 ? -11.586 38.018  -50.528 1.00 50.49  ? 435 LYS B HD3    1 
ATOM   14083 H HE2    . LYS B 1 435 ? -8.815  38.320  -50.096 1.00 73.11  ? 435 LYS B HE2    1 
ATOM   14084 H HE3    . LYS B 1 435 ? -9.427  37.829  -51.478 1.00 73.11  ? 435 LYS B HE3    1 
ATOM   14085 H HZ1    . LYS B 1 435 ? -8.977  40.052  -51.553 1.00 81.75  ? 435 LYS B HZ1    1 
ATOM   14086 H HZ2    . LYS B 1 435 ? -10.408 39.870  -51.688 1.00 81.75  ? 435 LYS B HZ2    1 
ATOM   14087 H HZ3    . LYS B 1 435 ? -9.850  40.318  -50.428 1.00 81.75  ? 435 LYS B HZ3    1 
ATOM   14088 N N      . GLY B 1 436 ? -14.862 38.348  -46.263 1.00 21.62  ? 436 GLY B N      1 
ATOM   14089 C CA     . GLY B 1 436 ? -16.091 37.712  -45.841 1.00 19.98  ? 436 GLY B CA     1 
ATOM   14090 C C      . GLY B 1 436 ? -16.297 36.391  -46.552 1.00 21.09  ? 436 GLY B C      1 
ATOM   14091 O O      . GLY B 1 436 ? -15.695 36.139  -47.603 1.00 20.25  ? 436 GLY B O      1 
ATOM   14092 H H      . GLY B 1 436 ? -14.974 39.038  -46.764 1.00 25.94  ? 436 GLY B H      1 
ATOM   14093 H HA2    . GLY B 1 436 ? -16.068 37.553  -44.884 1.00 23.98  ? 436 GLY B HA2    1 
ATOM   14094 H HA3    . GLY B 1 436 ? -16.841 38.292  -46.043 1.00 23.98  ? 436 GLY B HA3    1 
ATOM   14095 N N      . LEU B 1 437 ? -17.150 35.556  -45.967 1.00 19.01  ? 437 LEU B N      1 
ATOM   14096 C CA     . LEU B 1 437 ? -17.511 34.258  -46.530 1.00 19.28  ? 437 LEU B CA     1 
ATOM   14097 C C      . LEU B 1 437 ? -18.981 34.248  -46.899 1.00 23.41  ? 437 LEU B C      1 
ATOM   14098 O O      . LEU B 1 437 ? -19.766 35.045  -46.376 1.00 21.68  ? 437 LEU B O      1 
ATOM   14099 C CB     . LEU B 1 437 ? -17.225 33.122  -45.529 1.00 21.44  ? 437 LEU B CB     1 
ATOM   14100 C CG     . LEU B 1 437 ? -15.765 32.732  -45.296 1.00 20.64  ? 437 LEU B CG     1 
ATOM   14101 C CD1    . LEU B 1 437 ? -15.641 31.787  -44.113 1.00 20.92  ? 437 LEU B CD1    1 
ATOM   14102 C CD2    . LEU B 1 437 ? -15.156 32.095  -46.542 1.00 20.71  ? 437 LEU B CD2    1 
ATOM   14103 H H      . LEU B 1 437 ? -17.544 35.724  -45.221 1.00 22.81  ? 437 LEU B H      1 
ATOM   14104 H HA     . LEU B 1 437 ? -16.996 34.091  -47.334 1.00 23.13  ? 437 LEU B HA     1 
ATOM   14105 H HB2    . LEU B 1 437 ? -17.589 33.383  -44.669 1.00 25.72  ? 437 LEU B HB2    1 
ATOM   14106 H HB3    . LEU B 1 437 ? -17.685 32.326  -45.840 1.00 25.72  ? 437 LEU B HB3    1 
ATOM   14107 H HG     . LEU B 1 437 ? -15.256 33.532  -45.092 1.00 24.76  ? 437 LEU B HG     1 
ATOM   14108 H HD11   . LEU B 1 437 ? -14.707 31.552  -43.994 1.00 25.10  ? 437 LEU B HD11   1 
ATOM   14109 H HD12   . LEU B 1 437 ? -15.975 32.231  -43.318 1.00 25.10  ? 437 LEU B HD12   1 
ATOM   14110 H HD13   . LEU B 1 437 ? -16.163 30.989  -44.291 1.00 25.10  ? 437 LEU B HD13   1 
ATOM   14111 H HD21   . LEU B 1 437 ? -14.252 31.807  -46.339 1.00 24.86  ? 437 LEU B HD21   1 
ATOM   14112 H HD22   . LEU B 1 437 ? -15.696 31.332  -46.802 1.00 24.86  ? 437 LEU B HD22   1 
ATOM   14113 H HD23   . LEU B 1 437 ? -15.142 32.750  -47.257 1.00 24.86  ? 437 LEU B HD23   1 
ATOM   14114 N N      . LYS B 1 438 ? -19.338 33.348  -47.810 1.00 21.73  ? 438 LYS B N      1 
ATOM   14115 C CA     . LYS B 1 438 ? -20.733 33.042  -48.107 1.00 20.46  ? 438 LYS B CA     1 
ATOM   14116 C C      . LYS B 1 438 ? -20.896 31.535  -48.232 1.00 21.92  ? 438 LYS B C      1 
ATOM   14117 O O      . LYS B 1 438 ? -19.939 30.833  -48.555 1.00 21.51  ? 438 LYS B O      1 
ATOM   14118 C CB     . LYS B 1 438 ? -21.179 33.737  -49.394 1.00 26.91  ? 438 LYS B CB     1 
ATOM   14119 C CG     . LYS B 1 438 ? -20.443 33.250  -50.626 1.00 31.78  ? 438 LYS B CG     1 
ATOM   14120 C CD     . LYS B 1 438 ? -20.704 34.148  -51.811 1.00 39.70  ? 438 LYS B CD     1 
ATOM   14121 C CE     . LYS B 1 438 ? -20.021 33.616  -53.063 1.00 47.63  ? 438 LYS B CE     1 
ATOM   14122 N NZ     . LYS B 1 438 ? -20.029 34.651  -54.129 1.00 57.68  ? 438 LYS B NZ     1 
ATOM   14123 H H      . LYS B 1 438 ? -18.779 32.893  -48.278 1.00 26.07  ? 438 LYS B H      1 
ATOM   14124 H HA     . LYS B 1 438 ? -21.298 33.350  -47.381 1.00 24.56  ? 438 LYS B HA     1 
ATOM   14125 H HB2    . LYS B 1 438 ? -22.126 33.572  -49.528 1.00 32.30  ? 438 LYS B HB2    1 
ATOM   14126 H HB3    . LYS B 1 438 ? -21.018 34.690  -49.308 1.00 32.30  ? 438 LYS B HB3    1 
ATOM   14127 H HG2    . LYS B 1 438 ? -19.489 33.248  -50.451 1.00 38.14  ? 438 LYS B HG2    1 
ATOM   14128 H HG3    . LYS B 1 438 ? -20.747 32.356  -50.850 1.00 38.14  ? 438 LYS B HG3    1 
ATOM   14129 H HD2    . LYS B 1 438 ? -21.659 34.190  -51.978 1.00 47.64  ? 438 LYS B HD2    1 
ATOM   14130 H HD3    . LYS B 1 438 ? -20.355 35.034  -51.626 1.00 47.64  ? 438 LYS B HD3    1 
ATOM   14131 H HE2    . LYS B 1 438 ? -19.100 33.390  -52.859 1.00 57.16  ? 438 LYS B HE2    1 
ATOM   14132 H HE3    . LYS B 1 438 ? -20.499 32.836  -53.387 1.00 57.16  ? 438 LYS B HE3    1 
ATOM   14133 H HZ1    . LYS B 1 438 ? -19.769 35.433  -53.793 1.00 69.22  ? 438 LYS B HZ1    1 
ATOM   14134 H HZ2    . LYS B 1 438 ? -19.473 34.419  -54.783 1.00 69.22  ? 438 LYS B HZ2    1 
ATOM   14135 H HZ3    . LYS B 1 438 ? -20.850 34.739  -54.462 1.00 69.22  ? 438 LYS B HZ3    1 
ATOM   14136 N N      . PHE B 1 439 ? -22.104 31.045  -47.980 1.00 21.31  ? 439 PHE B N      1 
ATOM   14137 C CA     . PHE B 1 439 ? -22.423 29.637  -48.167 1.00 22.86  ? 439 PHE B CA     1 
ATOM   14138 C C      . PHE B 1 439 ? -22.289 29.209  -49.623 1.00 30.30  ? 439 PHE B C      1 
ATOM   14139 O O      . PHE B 1 439 ? -22.717 29.926  -50.527 1.00 26.49  ? 439 PHE B O      1 
ATOM   14140 C CB     . PHE B 1 439 ? -23.856 29.337  -47.717 1.00 24.75  ? 439 PHE B CB     1 
ATOM   14141 C CG     . PHE B 1 439 ? -24.035 29.221  -46.229 1.00 27.67  ? 439 PHE B CG     1 
ATOM   14142 C CD1    . PHE B 1 439 ? -23.646 28.074  -45.554 1.00 28.26  ? 439 PHE B CD1    1 
ATOM   14143 C CD2    . PHE B 1 439 ? -24.645 30.234  -45.512 1.00 27.11  ? 439 PHE B CD2    1 
ATOM   14144 C CE1    . PHE B 1 439 ? -23.835 27.956  -44.187 1.00 29.34  ? 439 PHE B CE1    1 
ATOM   14145 C CE2    . PHE B 1 439 ? -24.833 30.121  -44.150 1.00 27.09  ? 439 PHE B CE2    1 
ATOM   14146 C CZ     . PHE B 1 439 ? -24.427 28.983  -43.486 1.00 29.18  ? 439 PHE B CZ     1 
ATOM   14147 H H      . PHE B 1 439 ? -22.765 31.516  -47.696 1.00 25.57  ? 439 PHE B H      1 
ATOM   14148 H HA     . PHE B 1 439 ? -21.817 29.098  -47.634 1.00 27.44  ? 439 PHE B HA     1 
ATOM   14149 H HB2    . PHE B 1 439 ? -24.434 30.051  -48.027 1.00 29.70  ? 439 PHE B HB2    1 
ATOM   14150 H HB3    . PHE B 1 439 ? -24.135 28.497  -48.113 1.00 29.70  ? 439 PHE B HB3    1 
ATOM   14151 H HD1    . PHE B 1 439 ? -23.244 27.379  -46.023 1.00 33.92  ? 439 PHE B HD1    1 
ATOM   14152 H HD2    . PHE B 1 439 ? -24.920 31.006  -45.951 1.00 32.53  ? 439 PHE B HD2    1 
ATOM   14153 H HE1    . PHE B 1 439 ? -23.559 27.187  -43.743 1.00 35.20  ? 439 PHE B HE1    1 
ATOM   14154 H HE2    . PHE B 1 439 ? -25.234 30.815  -43.678 1.00 32.51  ? 439 PHE B HE2    1 
ATOM   14155 H HZ     . PHE B 1 439 ? -24.554 28.908  -42.568 1.00 35.02  ? 439 PHE B HZ     1 
ATOM   14156 N N      . VAL B 1 440 ? -21.707 28.035  -49.847 1.00 24.46  ? 440 VAL B N      1 
ATOM   14157 C CA     . VAL B 1 440 ? -21.869 27.346  -51.126 1.00 24.47  ? 440 VAL B CA     1 
ATOM   14158 C C      . VAL B 1 440 ? -22.578 26.021  -50.885 1.00 26.13  ? 440 VAL B C      1 
ATOM   14159 O O      . VAL B 1 440 ? -23.122 25.426  -51.812 1.00 30.81  ? 440 VAL B O      1 
ATOM   14160 C CB     . VAL B 1 440 ? -20.527 27.100  -51.862 1.00 29.45  ? 440 VAL B CB     1 
ATOM   14161 C CG1    . VAL B 1 440 ? -19.921 28.418  -52.327 1.00 28.03  ? 440 VAL B CG1    1 
ATOM   14162 C CG2    . VAL B 1 440 ? -19.561 26.313  -51.006 1.00 28.86  ? 440 VAL B CG2    1 
ATOM   14163 H H      . VAL B 1 440 ? -21.215 27.618  -49.279 1.00 29.35  ? 440 VAL B H      1 
ATOM   14164 H HA     . VAL B 1 440 ? -22.432 27.874  -51.713 1.00 29.37  ? 440 VAL B HA     1 
ATOM   14165 H HB     . VAL B 1 440 ? -20.707 26.570  -52.654 1.00 35.34  ? 440 VAL B HB     1 
ATOM   14166 H HG11   . VAL B 1 440 ? -19.066 28.240  -52.749 1.00 33.64  ? 440 VAL B HG11   1 
ATOM   14167 H HG12   . VAL B 1 440 ? -20.523 28.836  -52.962 1.00 33.64  ? 440 VAL B HG12   1 
ATOM   14168 H HG13   . VAL B 1 440 ? -19.796 28.996  -51.558 1.00 33.64  ? 440 VAL B HG13   1 
ATOM   14169 H HG21   . VAL B 1 440 ? -18.719 26.228  -51.480 1.00 34.64  ? 440 VAL B HG21   1 
ATOM   14170 H HG22   . VAL B 1 440 ? -19.423 26.785  -50.170 1.00 34.64  ? 440 VAL B HG22   1 
ATOM   14171 H HG23   . VAL B 1 440 ? -19.932 25.434  -50.833 1.00 34.64  ? 440 VAL B HG23   1 
ATOM   14172 N N      . TYR B 1 441 ? -22.558 25.543  -49.644 1.00 25.14  ? 441 TYR B N      1 
ATOM   14173 C CA     . TYR B 1 441 ? -23.396 24.411  -49.250 1.00 26.18  ? 441 TYR B CA     1 
ATOM   14174 C C      . TYR B 1 441 ? -23.856 24.568  -47.815 1.00 28.54  ? 441 TYR B C      1 
ATOM   14175 O O      . TYR B 1 441 ? -23.036 24.722  -46.909 1.00 25.18  ? 441 TYR B O      1 
ATOM   14176 C CB     . TYR B 1 441 ? -22.665 23.074  -49.399 1.00 28.83  ? 441 TYR B CB     1 
ATOM   14177 C CG     . TYR B 1 441 ? -23.387 21.948  -48.693 1.00 29.48  ? 441 TYR B CG     1 
ATOM   14178 C CD1    . TYR B 1 441 ? -24.591 21.450  -49.184 1.00 33.97  ? 441 TYR B CD1    1 
ATOM   14179 C CD2    . TYR B 1 441 ? -22.879 21.392  -47.527 1.00 29.08  ? 441 TYR B CD2    1 
ATOM   14180 C CE1    . TYR B 1 441 ? -25.265 20.430  -48.531 1.00 34.07  ? 441 TYR B CE1    1 
ATOM   14181 C CE2    . TYR B 1 441 ? -23.546 20.371  -46.866 1.00 31.60  ? 441 TYR B CE2    1 
ATOM   14182 C CZ     . TYR B 1 441 ? -24.737 19.892  -47.372 1.00 35.95  ? 441 TYR B CZ     1 
ATOM   14183 O OH     . TYR B 1 441 ? -25.397 18.872  -46.720 1.00 35.47  ? 441 TYR B OH     1 
ATOM   14184 H H      . TYR B 1 441 ? -22.067 25.852  -49.009 1.00 30.17  ? 441 TYR B H      1 
ATOM   14185 H HA     . TYR B 1 441 ? -24.185 24.386  -49.813 1.00 31.41  ? 441 TYR B HA     1 
ATOM   14186 H HB2    . TYR B 1 441 ? -22.602 22.849  -50.340 1.00 34.60  ? 441 TYR B HB2    1 
ATOM   14187 H HB3    . TYR B 1 441 ? -21.779 23.152  -49.014 1.00 34.60  ? 441 TYR B HB3    1 
ATOM   14188 H HD1    . TYR B 1 441 ? -24.952 21.811  -49.961 1.00 40.76  ? 441 TYR B HD1    1 
ATOM   14189 H HD2    . TYR B 1 441 ? -22.078 21.714  -47.180 1.00 34.90  ? 441 TYR B HD2    1 
ATOM   14190 H HE1    . TYR B 1 441 ? -26.067 20.106  -48.873 1.00 40.89  ? 441 TYR B HE1    1 
ATOM   14191 H HE2    . TYR B 1 441 ? -23.190 20.008  -46.088 1.00 37.91  ? 441 TYR B HE2    1 
ATOM   14192 H HH     . TYR B 1 441 ? -26.102 18.676  -47.133 1.00 42.57  ? 441 TYR B HH     1 
ATOM   14193 N N      . GLU B 1 442 ? -25.169 24.517  -47.612 1.00 28.63  ? 442 GLU B N      1 
ATOM   14194 C CA     . GLU B 1 442 ? -25.741 24.629  -46.281 1.00 28.85  ? 442 GLU B CA     1 
ATOM   14195 C C      . GLU B 1 442 ? -26.664 23.445  -45.980 1.00 33.84  ? 442 GLU B C      1 
ATOM   14196 O O      . GLU B 1 442 ? -27.675 23.256  -46.669 1.00 32.08  ? 442 GLU B O      1 
ATOM   14197 C CB     . GLU B 1 442 ? -26.518 25.934  -46.129 1.00 27.92  ? 442 GLU B CB     1 
ATOM   14198 C CG     . GLU B 1 442 ? -27.096 26.100  -44.728 1.00 33.70  ? 442 GLU B CG     1 
ATOM   14199 C CD     . GLU B 1 442 ? -27.817 27.419  -44.526 1.00 31.53  ? 442 GLU B CD     1 
ATOM   14200 O OE1    . GLU B 1 442 ? -28.329 27.641  -43.411 1.00 30.28  ? 442 GLU B OE1    1 
ATOM   14201 O OE2    . GLU B 1 442 ? -27.882 28.220  -45.477 1.00 31.14  ? 442 GLU B OE2    1 
ATOM   14202 H H      . GLU B 1 442 ? -25.752 24.417  -48.236 1.00 34.35  ? 442 GLU B H      1 
ATOM   14203 H HA     . GLU B 1 442 ? -25.030 24.658  -45.629 1.00 34.61  ? 442 GLU B HA     1 
ATOM   14204 H HB2    . GLU B 1 442 ? -25.924 26.680  -46.302 1.00 33.50  ? 442 GLU B HB2    1 
ATOM   14205 H HB3    . GLU B 1 442 ? -27.254 25.940  -46.761 1.00 33.50  ? 442 GLU B HB3    1 
ATOM   14206 H HG2    . GLU B 1 442 ? -27.737 25.392  -44.562 1.00 40.44  ? 442 GLU B HG2    1 
ATOM   14207 H HG3    . GLU B 1 442 ? -26.374 26.051  -44.082 1.00 40.44  ? 442 GLU B HG3    1 
ATOM   14208 N N      . PRO B 1 443 ? -26.328 22.649  -44.946 1.00 34.34  ? 443 PRO B N      1 
ATOM   14209 C CA     . PRO B 1 443 ? -27.240 21.582  -44.518 1.00 36.12  ? 443 PRO B CA     1 
ATOM   14210 C C      . PRO B 1 443 ? -28.475 22.165  -43.842 1.00 36.69  ? 443 PRO B C      1 
ATOM   14211 O O      . PRO B 1 443 ? -28.404 23.286  -43.342 1.00 31.26  ? 443 PRO B O      1 
ATOM   14212 C CB     . PRO B 1 443 ? -26.408 20.769  -43.518 1.00 33.99  ? 443 PRO B CB     1 
ATOM   14213 C CG     . PRO B 1 443 ? -25.019 21.321  -43.583 1.00 39.66  ? 443 PRO B CG     1 
ATOM   14214 C CD     . PRO B 1 443 ? -25.141 22.717  -44.077 1.00 38.26  ? 443 PRO B CD     1 
ATOM   14215 H HA     . PRO B 1 443 ? -27.500 21.023  -45.267 1.00 43.35  ? 443 PRO B HA     1 
ATOM   14216 H HB2    . PRO B 1 443 ? -26.776 20.878  -42.627 1.00 40.79  ? 443 PRO B HB2    1 
ATOM   14217 H HB3    . PRO B 1 443 ? -26.414 19.834  -43.776 1.00 40.79  ? 443 PRO B HB3    1 
ATOM   14218 H HG2    . PRO B 1 443 ? -24.624 21.308  -42.697 1.00 47.59  ? 443 PRO B HG2    1 
ATOM   14219 H HG3    . PRO B 1 443 ? -24.490 20.790  -44.199 1.00 47.59  ? 443 PRO B HG3    1 
ATOM   14220 H HD2    . PRO B 1 443 ? -25.291 23.329  -43.340 1.00 45.92  ? 443 PRO B HD2    1 
ATOM   14221 H HD3    . PRO B 1 443 ? -24.351 22.953  -44.586 1.00 45.92  ? 443 PRO B HD3    1 
ATOM   14222 N N      . LYS B 1 444 ? -29.575 21.418  -43.814 1.00 35.81  ? 444 LYS B N      1 
ATOM   14223 C CA     . LYS B 1 444 ? -30.815 21.920  -43.232 1.00 41.12  ? 444 LYS B CA     1 
ATOM   14224 C C      . LYS B 1 444 ? -30.753 21.952  -41.702 1.00 38.05  ? 444 LYS B C      1 
ATOM   14225 O O      . LYS B 1 444 ? -31.548 22.638  -41.061 1.00 36.55  ? 444 LYS B O      1 
ATOM   14226 C CB     . LYS B 1 444 ? -32.009 21.077  -43.706 1.00 47.21  ? 444 LYS B CB     1 
ATOM   14227 C CG     . LYS B 1 444 ? -32.784 21.696  -44.880 1.00 53.68  ? 444 LYS B CG     1 
ATOM   14228 C CD     . LYS B 1 444 ? -31.874 22.054  -46.062 1.00 78.40  ? 444 LYS B CD     1 
ATOM   14229 C CE     . LYS B 1 444 ? -32.649 22.702  -47.205 1.00 88.04  ? 444 LYS B CE     1 
ATOM   14230 N NZ     . LYS B 1 444 ? -31.763 23.061  -48.353 1.00 85.17  ? 444 LYS B NZ     1 
ATOM   14231 H H      . LYS B 1 444 ? -29.628 20.618  -44.125 1.00 42.97  ? 444 LYS B H      1 
ATOM   14232 H HA     . LYS B 1 444 ? -30.956 22.830  -43.537 1.00 49.34  ? 444 LYS B HA     1 
ATOM   14233 H HB2    . LYS B 1 444 ? -31.686 20.208  -43.990 1.00 56.65  ? 444 LYS B HB2    1 
ATOM   14234 H HB3    . LYS B 1 444 ? -32.628 20.971  -42.967 1.00 56.65  ? 444 LYS B HB3    1 
ATOM   14235 H HG2    . LYS B 1 444 ? -33.447 21.060  -45.192 1.00 64.41  ? 444 LYS B HG2    1 
ATOM   14236 H HG3    . LYS B 1 444 ? -33.219 22.509  -44.579 1.00 64.41  ? 444 LYS B HG3    1 
ATOM   14237 H HD2    . LYS B 1 444 ? -31.196 22.682  -45.770 1.00 94.08  ? 444 LYS B HD2    1 
ATOM   14238 H HD3    . LYS B 1 444 ? -31.458 21.245  -46.399 1.00 94.08  ? 444 LYS B HD3    1 
ATOM   14239 H HE2    . LYS B 1 444 ? -33.322 22.081  -47.525 1.00 105.65 ? 444 LYS B HE2    1 
ATOM   14240 H HE3    . LYS B 1 444 ? -33.070 23.514  -46.883 1.00 105.65 ? 444 LYS B HE3    1 
ATOM   14241 H HZ1    . LYS B 1 444 ? -32.243 23.436  -49.002 1.00 102.20 ? 444 LYS B HZ1    1 
ATOM   14242 H HZ2    . LYS B 1 444 ? -31.138 23.636  -48.086 1.00 102.20 ? 444 LYS B HZ2    1 
ATOM   14243 H HZ3    . LYS B 1 444 ? -31.367 22.330  -48.671 1.00 102.20 ? 444 LYS B HZ3    1 
ATOM   14244 N N      . GLN B 1 445 ? -29.816 21.212  -41.113 1.00 38.91  ? 445 GLN B N      1 
ATOM   14245 C CA     . GLN B 1 445 ? -29.599 21.300  -39.668 1.00 39.79  ? 445 GLN B CA     1 
ATOM   14246 C C      . GLN B 1 445 ? -28.153 20.967  -39.286 1.00 36.96  ? 445 GLN B C      1 
ATOM   14247 O O      . GLN B 1 445 ? -27.380 20.468  -40.111 1.00 32.38  ? 445 GLN B O      1 
ATOM   14248 C CB     . GLN B 1 445 ? -30.574 20.384  -38.925 1.00 45.15  ? 445 GLN B CB     1 
ATOM   14249 C CG     . GLN B 1 445 ? -30.360 18.893  -39.131 1.00 44.42  ? 445 GLN B CG     1 
ATOM   14250 C CD     . GLN B 1 445 ? -30.944 18.383  -40.433 1.00 50.48  ? 445 GLN B CD     1 
ATOM   14251 O OE1    . GLN B 1 445 ? -31.069 19.121  -41.407 1.00 60.18  ? 445 GLN B OE1    1 
ATOM   14252 N NE2    . GLN B 1 445 ? -31.314 17.112  -40.451 1.00 56.85  ? 445 GLN B NE2    1 
ATOM   14253 H H      . GLN B 1 445 ? -29.299 20.658  -41.519 1.00 46.69  ? 445 GLN B H      1 
ATOM   14254 H HA     . GLN B 1 445 ? -29.772 22.210  -39.379 1.00 47.75  ? 445 GLN B HA     1 
ATOM   14255 H HB2    . GLN B 1 445 ? -30.497 20.559  -37.975 1.00 54.18  ? 445 GLN B HB2    1 
ATOM   14256 H HB3    . GLN B 1 445 ? -31.474 20.592  -39.220 1.00 54.18  ? 445 GLN B HB3    1 
ATOM   14257 H HG2    . GLN B 1 445 ? -29.411 18.696  -39.133 1.00 53.31  ? 445 GLN B HG2    1 
ATOM   14258 H HG3    . GLN B 1 445 ? -30.792 18.414  -38.407 1.00 53.31  ? 445 GLN B HG3    1 
ATOM   14259 H HE21   . GLN B 1 445 ? -31.199 16.621  -39.755 1.00 68.22  ? 445 GLN B HE21   1 
ATOM   14260 H HE22   . GLN B 1 445 ? -31.669 16.778  -41.159 1.00 68.22  ? 445 GLN B HE22   1 
ATOM   14261 N N      . LEU B 1 446 ? -27.804 21.252  -38.033 1.00 32.57  ? 446 LEU B N      1 
ATOM   14262 C CA     . LEU B 1 446 ? -26.434 21.099  -37.548 1.00 33.49  ? 446 LEU B CA     1 
ATOM   14263 C C      . LEU B 1 446 ? -25.460 21.711  -38.558 1.00 31.11  ? 446 LEU B C      1 
ATOM   14264 O O      . LEU B 1 446 ? -24.439 21.111  -38.899 1.00 26.66  ? 446 LEU B O      1 
ATOM   14265 C CB     . LEU B 1 446 ? -26.112 19.616  -37.306 1.00 31.92  ? 446 LEU B CB     1 
ATOM   14266 C CG     . LEU B 1 446 ? -25.180 19.318  -36.128 1.00 33.39  ? 446 LEU B CG     1 
ATOM   14267 C CD1    . LEU B 1 446 ? -25.906 19.555  -34.813 1.00 35.49  ? 446 LEU B CD1    1 
ATOM   14268 C CD2    . LEU B 1 446 ? -24.640 17.891  -36.191 1.00 34.62  ? 446 LEU B CD2    1 
ATOM   14269 H H      . LEU B 1 446 ? -28.351 21.540  -37.436 1.00 39.09  ? 446 LEU B H      1 
ATOM   14270 H HA     . LEU B 1 446 ? -26.337 21.575  -36.709 1.00 40.18  ? 446 LEU B HA     1 
ATOM   14271 H HB2    . LEU B 1 446 ? -26.947 19.155  -37.128 1.00 38.31  ? 446 LEU B HB2    1 
ATOM   14272 H HB3    . LEU B 1 446 ? -25.709 19.241  -38.104 1.00 38.31  ? 446 LEU B HB3    1 
ATOM   14273 H HG     . LEU B 1 446 ? -24.424 19.925  -36.165 1.00 40.07  ? 446 LEU B HG     1 
ATOM   14274 H HD11   . LEU B 1 446 ? -25.308 19.338  -34.081 1.00 42.59  ? 446 LEU B HD11   1 
ATOM   14275 H HD12   . LEU B 1 446 ? -26.169 20.486  -34.759 1.00 42.59  ? 446 LEU B HD12   1 
ATOM   14276 H HD13   . LEU B 1 446 ? -26.691 18.986  -34.779 1.00 42.59  ? 446 LEU B HD13   1 
ATOM   14277 H HD21   . LEU B 1 446 ? -24.057 17.741  -35.431 1.00 41.55  ? 446 LEU B HD21   1 
ATOM   14278 H HD22   . LEU B 1 446 ? -25.385 17.270  -36.165 1.00 41.55  ? 446 LEU B HD22   1 
ATOM   14279 H HD23   . LEU B 1 446 ? -24.144 17.778  -37.017 1.00 41.55  ? 446 LEU B HD23   1 
ATOM   14280 N N      . ARG B 1 447 ? -25.781 22.905  -39.050 1.00 29.45  ? 447 ARG B N      1 
ATOM   14281 C CA     . ARG B 1 447 ? -25.098 23.411  -40.235 1.00 28.67  ? 447 ARG B CA     1 
ATOM   14282 C C      . ARG B 1 447 ? -23.620 23.688  -39.987 1.00 23.45  ? 447 ARG B C      1 
ATOM   14283 O O      . ARG B 1 447 ? -22.816 23.625  -40.917 1.00 26.75  ? 447 ARG B O      1 
ATOM   14284 C CB     . ARG B 1 447 ? -25.788 24.679  -40.768 1.00 30.94  ? 447 ARG B CB     1 
ATOM   14285 C CG     . ARG B 1 447 ? -25.624 25.938  -39.919 1.00 27.32  ? 447 ARG B CG     1 
ATOM   14286 C CD     . ARG B 1 447 ? -26.326 27.110  -40.609 1.00 27.07  ? 447 ARG B CD     1 
ATOM   14287 N NE     . ARG B 1 447 ? -26.221 28.361  -39.859 1.00 24.52  ? 447 ARG B NE     1 
ATOM   14288 C CZ     . ARG B 1 447 ? -26.801 29.496  -40.238 1.00 29.70  ? 447 ARG B CZ     1 
ATOM   14289 N NH1    . ARG B 1 447 ? -27.517 29.527  -41.357 1.00 27.80  ? 447 ARG B NH1    1 
ATOM   14290 N NH2    . ARG B 1 447 ? -26.662 30.598  -39.506 1.00 26.66  ? 447 ARG B NH2    1 
ATOM   14291 H H      . ARG B 1 447 ? -26.378 23.431  -38.724 1.00 35.34  ? 447 ARG B H      1 
ATOM   14292 H HA     . ARG B 1 447 ? -25.153 22.737  -40.930 1.00 34.40  ? 447 ARG B HA     1 
ATOM   14293 H HB2    . ARG B 1 447 ? -25.428 24.876  -41.647 1.00 37.12  ? 447 ARG B HB2    1 
ATOM   14294 H HB3    . ARG B 1 447 ? -26.739 24.501  -40.841 1.00 37.12  ? 447 ARG B HB3    1 
ATOM   14295 H HG2    . ARG B 1 447 ? -26.030 25.801  -39.049 1.00 32.78  ? 447 ARG B HG2    1 
ATOM   14296 H HG3    . ARG B 1 447 ? -24.683 26.154  -39.827 1.00 32.78  ? 447 ARG B HG3    1 
ATOM   14297 H HD2    . ARG B 1 447 ? -25.924 27.249  -41.481 1.00 32.49  ? 447 ARG B HD2    1 
ATOM   14298 H HD3    . ARG B 1 447 ? -27.268 26.899  -40.708 1.00 32.49  ? 447 ARG B HD3    1 
ATOM   14299 H HE     . ARG B 1 447 ? -25.866 28.332  -39.076 1.00 29.42  ? 447 ARG B HE     1 
ATOM   14300 H HH11   . ARG B 1 447 ? -27.609 28.817  -41.833 1.00 33.36  ? 447 ARG B HH11   1 
ATOM   14301 H HH12   . ARG B 1 447 ? -27.893 30.258  -41.605 1.00 33.36  ? 447 ARG B HH12   1 
ATOM   14302 H HH21   . ARG B 1 447 ? -26.198 30.578  -38.782 1.00 32.00  ? 447 ARG B HH21   1 
ATOM   14303 H HH22   . ARG B 1 447 ? -27.038 31.330  -39.755 1.00 32.00  ? 447 ARG B HH22   1 
ATOM   14304 N N      . PHE B 1 448 ? -23.249 23.981  -38.747 1.00 22.26  ? 448 PHE B N      1 
ATOM   14305 C CA     . PHE B 1 448 ? -21.851 24.292  -38.446 1.00 26.55  ? 448 PHE B CA     1 
ATOM   14306 C C      . PHE B 1 448 ? -20.956 23.084  -38.693 1.00 25.40  ? 448 PHE B C      1 
ATOM   14307 O O      . PHE B 1 448 ? -19.761 23.231  -38.944 1.00 24.86  ? 448 PHE B O      1 
ATOM   14308 C CB     . PHE B 1 448 ? -21.702 24.762  -37.002 1.00 26.93  ? 448 PHE B CB     1 
ATOM   14309 C CG     . PHE B 1 448 ? -22.098 23.726  -35.985 1.00 26.38  ? 448 PHE B CG     1 
ATOM   14310 C CD1    . PHE B 1 448 ? -21.182 22.779  -35.548 1.00 31.83  ? 448 PHE B CD1    1 
ATOM   14311 C CD2    . PHE B 1 448 ? -23.389 23.687  -35.478 1.00 34.65  ? 448 PHE B CD2    1 
ATOM   14312 C CE1    . PHE B 1 448 ? -21.540 21.824  -34.614 1.00 32.59  ? 448 PHE B CE1    1 
ATOM   14313 C CE2    . PHE B 1 448 ? -23.756 22.729  -34.544 1.00 35.36  ? 448 PHE B CE2    1 
ATOM   14314 C CZ     . PHE B 1 448 ? -22.829 21.794  -34.114 1.00 35.24  ? 448 PHE B CZ     1 
ATOM   14315 H H      . PHE B 1 448 ? -23.777 24.008  -38.069 1.00 26.71  ? 448 PHE B H      1 
ATOM   14316 H HA     . PHE B 1 448 ? -21.554 25.009  -39.027 1.00 31.86  ? 448 PHE B HA     1 
ATOM   14317 H HB2    . PHE B 1 448 ? -20.774 24.995  -36.843 1.00 32.31  ? 448 PHE B HB2    1 
ATOM   14318 H HB3    . PHE B 1 448 ? -22.264 25.540  -36.871 1.00 32.31  ? 448 PHE B HB3    1 
ATOM   14319 H HD1    . PHE B 1 448 ? -20.313 22.793  -35.880 1.00 38.19  ? 448 PHE B HD1    1 
ATOM   14320 H HD2    . PHE B 1 448 ? -24.014 24.313  -35.764 1.00 41.58  ? 448 PHE B HD2    1 
ATOM   14321 H HE1    . PHE B 1 448 ? -20.916 21.197  -34.328 1.00 39.11  ? 448 PHE B HE1    1 
ATOM   14322 H HE2    . PHE B 1 448 ? -24.623 22.714  -34.208 1.00 42.43  ? 448 PHE B HE2    1 
ATOM   14323 H HZ     . PHE B 1 448 ? -23.071 21.151  -33.487 1.00 42.29  ? 448 PHE B HZ     1 
ATOM   14324 N N      . PHE B 1 449 ? -21.552 21.896  -38.640 1.00 23.37  ? 449 PHE B N      1 
ATOM   14325 C CA     . PHE B 1 449 ? -20.807 20.639  -38.706 1.00 25.22  ? 449 PHE B CA     1 
ATOM   14326 C C      . PHE B 1 449 ? -20.304 20.328  -40.125 1.00 26.08  ? 449 PHE B C      1 
ATOM   14327 O O      . PHE B 1 449 ? -19.191 19.828  -40.284 1.00 27.21  ? 449 PHE B O      1 
ATOM   14328 C CB     . PHE B 1 449 ? -21.700 19.499  -38.175 1.00 28.75  ? 449 PHE B CB     1 
ATOM   14329 C CG     . PHE B 1 449 ? -20.973 18.202  -37.923 1.00 31.11  ? 449 PHE B CG     1 
ATOM   14330 C CD1    . PHE B 1 449 ? -19.953 18.132  -36.989 1.00 34.80  ? 449 PHE B CD1    1 
ATOM   14331 C CD2    . PHE B 1 449 ? -21.338 17.043  -38.599 1.00 34.95  ? 449 PHE B CD2    1 
ATOM   14332 C CE1    . PHE B 1 449 ? -19.286 16.935  -36.748 1.00 34.40  ? 449 PHE B CE1    1 
ATOM   14333 C CE2    . PHE B 1 449 ? -20.676 15.843  -38.362 1.00 35.30  ? 449 PHE B CE2    1 
ATOM   14334 C CZ     . PHE B 1 449 ? -19.649 15.793  -37.431 1.00 28.86  ? 449 PHE B CZ     1 
ATOM   14335 H H      . PHE B 1 449 ? -22.401 21.786  -38.564 1.00 28.04  ? 449 PHE B H      1 
ATOM   14336 H HA     . PHE B 1 449 ? -20.033 20.705  -38.126 1.00 30.26  ? 449 PHE B HA     1 
ATOM   14337 H HB2    . PHE B 1 449 ? -22.098 19.781  -37.336 1.00 34.50  ? 449 PHE B HB2    1 
ATOM   14338 H HB3    . PHE B 1 449 ? -22.398 19.323  -38.825 1.00 34.50  ? 449 PHE B HB3    1 
ATOM   14339 H HD1    . PHE B 1 449 ? -19.701 18.898  -36.526 1.00 41.76  ? 449 PHE B HD1    1 
ATOM   14340 H HD2    . PHE B 1 449 ? -22.025 17.073  -39.225 1.00 41.94  ? 449 PHE B HD2    1 
ATOM   14341 H HE1    . PHE B 1 449 ? -18.598 16.904  -36.123 1.00 41.27  ? 449 PHE B HE1    1 
ATOM   14342 H HE2    . PHE B 1 449 ? -20.923 15.075  -38.825 1.00 42.37  ? 449 PHE B HE2    1 
ATOM   14343 H HZ     . PHE B 1 449 ? -19.205 14.992  -37.269 1.00 34.63  ? 449 PHE B HZ     1 
ATOM   14344 N N      . THR B 1 450 ? -21.108 20.630  -41.149 1.00 23.56  ? 450 THR B N      1 
ATOM   14345 C CA     . THR B 1 450 ? -20.776 20.240  -42.526 1.00 26.02  ? 450 THR B CA     1 
ATOM   14346 C C      . THR B 1 450 ? -20.976 21.334  -43.587 1.00 25.20  ? 450 THR B C      1 
ATOM   14347 O O      . THR B 1 450 ? -20.801 21.076  -44.784 1.00 26.13  ? 450 THR B O      1 
ATOM   14348 C CB     . THR B 1 450 ? -21.606 19.003  -42.957 1.00 29.01  ? 450 THR B CB     1 
ATOM   14349 O OG1    . THR B 1 450 ? -23.002 19.264  -42.781 1.00 30.32  ? 450 THR B OG1    1 
ATOM   14350 C CG2    . THR B 1 450 ? -21.223 17.796  -42.133 1.00 30.37  ? 450 THR B CG2    1 
ATOM   14351 H H      . THR B 1 450 ? -21.850 21.059  -41.074 1.00 28.27  ? 450 THR B H      1 
ATOM   14352 H HA     . THR B 1 450 ? -19.842 19.984  -42.565 1.00 31.22  ? 450 THR B HA     1 
ATOM   14353 H HB     . THR B 1 450 ? -21.431 18.802  -43.889 1.00 34.82  ? 450 THR B HB     1 
ATOM   14354 H HG1    . THR B 1 450 ? -23.164 19.427  -41.973 1.00 36.39  ? 450 THR B HG1    1 
ATOM   14355 H HG21   . THR B 1 450 ? -21.724 17.020  -42.429 1.00 36.45  ? 450 THR B HG21   1 
ATOM   14356 H HG22   . THR B 1 450 ? -20.275 17.615  -42.230 1.00 36.45  ? 450 THR B HG22   1 
ATOM   14357 H HG23   . THR B 1 450 ? -21.419 17.960  -41.198 1.00 36.45  ? 450 THR B HG23   1 
ATOM   14358 N N      . ALA B 1 451 ? -21.316 22.550  -43.171 1.00 23.30  ? 451 ALA B N      1 
ATOM   14359 C CA     . ALA B 1 451 ? -21.467 23.648  -44.128 1.00 23.30  ? 451 ALA B CA     1 
ATOM   14360 C C      . ALA B 1 451 ? -20.151 23.965  -44.841 1.00 26.79  ? 451 ALA B C      1 
ATOM   14361 O O      . ALA B 1 451 ? -19.073 23.798  -44.271 1.00 23.26  ? 451 ALA B O      1 
ATOM   14362 C CB     . ALA B 1 451 ? -21.993 24.888  -43.435 1.00 26.61  ? 451 ALA B CB     1 
ATOM   14363 H H      . ALA B 1 451 ? -21.464 22.767  -42.352 1.00 27.96  ? 451 ALA B H      1 
ATOM   14364 H HA     . ALA B 1 451 ? -22.113 23.388  -44.803 1.00 27.96  ? 451 ALA B HA     1 
ATOM   14365 H HB1    . ALA B 1 451 ? -21.970 25.629  -44.061 1.00 31.94  ? 451 ALA B HB1    1 
ATOM   14366 H HB2    . ALA B 1 451 ? -22.905 24.728  -43.148 1.00 31.94  ? 451 ALA B HB2    1 
ATOM   14367 H HB3    . ALA B 1 451 ? -21.430 25.086  -42.671 1.00 31.94  ? 451 ALA B HB3    1 
ATOM   14368 N N      . ARG B 1 452 ? -20.249 24.416  -46.092 1.00 22.21  ? 452 ARG B N      1 
ATOM   14369 C CA     . ARG B 1 452 ? -19.082 24.831  -46.873 1.00 22.40  ? 452 ARG B CA     1 
ATOM   14370 C C      . ARG B 1 452 ? -19.276 26.249  -47.379 1.00 22.74  ? 452 ARG B C      1 
ATOM   14371 O O      . ARG B 1 452 ? -20.394 26.652  -47.704 1.00 23.88  ? 452 ARG B O      1 
ATOM   14372 C CB     . ARG B 1 452 ? -18.835 23.893  -48.060 1.00 25.37  ? 452 ARG B CB     1 
ATOM   14373 C CG     . ARG B 1 452 ? -18.373 22.493  -47.669 1.00 26.87  ? 452 ARG B CG     1 
ATOM   14374 C CD     . ARG B 1 452 ? -17.819 21.723  -48.870 1.00 35.39  ? 452 ARG B CD     1 
ATOM   14375 N NE     . ARG B 1 452 ? -18.886 21.157  -49.691 1.00 42.26  ? 452 ARG B NE     1 
ATOM   14376 C CZ     . ARG B 1 452 ? -19.295 21.638  -50.866 1.00 58.72  ? 452 ARG B CZ     1 
ATOM   14377 N NH1    . ARG B 1 452 ? -18.731 22.714  -51.407 1.00 49.04  ? 452 ARG B NH1    1 
ATOM   14378 N NH2    . ARG B 1 452 ? -20.281 21.027  -51.511 1.00 57.85  ? 452 ARG B NH2    1 
ATOM   14379 H H      . ARG B 1 452 ? -20.993 24.492  -46.517 1.00 26.65  ? 452 ARG B H      1 
ATOM   14380 H HA     . ARG B 1 452 ? -18.290 24.821  -46.314 1.00 26.88  ? 452 ARG B HA     1 
ATOM   14381 H HB2    . ARG B 1 452 ? -19.660 23.802  -48.562 1.00 30.45  ? 452 ARG B HB2    1 
ATOM   14382 H HB3    . ARG B 1 452 ? -18.150 24.283  -48.625 1.00 30.45  ? 452 ARG B HB3    1 
ATOM   14383 H HG2    . ARG B 1 452 ? -17.671 22.563  -47.003 1.00 32.24  ? 452 ARG B HG2    1 
ATOM   14384 H HG3    . ARG B 1 452 ? -19.126 21.997  -47.311 1.00 32.24  ? 452 ARG B HG3    1 
ATOM   14385 H HD2    . ARG B 1 452 ? -17.278 22.316  -49.411 1.00 42.47  ? 452 ARG B HD2    1 
ATOM   14386 H HD3    . ARG B 1 452 ? -17.275 20.989  -48.545 1.00 42.47  ? 452 ARG B HD3    1 
ATOM   14387 H HE     . ARG B 1 452 ? -19.284 20.455  -49.392 1.00 50.72  ? 452 ARG B HE     1 
ATOM   14388 H HH11   . ARG B 1 452 ? -18.093 23.122  -51.003 1.00 58.85  ? 452 ARG B HH11   1 
ATOM   14389 H HH12   . ARG B 1 452 ? -19.011 23.006  -52.166 1.00 58.85  ? 452 ARG B HH12   1 
ATOM   14390 H HH21   . ARG B 1 452 ? -20.651 20.329  -51.170 1.00 69.42  ? 452 ARG B HH21   1 
ATOM   14391 H HH22   . ARG B 1 452 ? -20.550 21.328  -52.270 1.00 69.42  ? 452 ARG B HH22   1 
ATOM   14392 N N      . PHE B 1 453 ? -18.169 26.974  -47.481 1.00 19.63  ? 453 PHE B N      1 
ATOM   14393 C CA     . PHE B 1 453 ? -18.189 28.387  -47.801 1.00 19.89  ? 453 PHE B CA     1 
ATOM   14394 C C      . PHE B 1 453 ? -17.194 28.690  -48.906 1.00 21.96  ? 453 PHE B C      1 
ATOM   14395 O O      . PHE B 1 453 ? -16.326 27.875  -49.211 1.00 21.97  ? 453 PHE B O      1 
ATOM   14396 C CB     . PHE B 1 453 ? -17.845 29.219  -46.559 1.00 20.73  ? 453 PHE B CB     1 
ATOM   14397 C CG     . PHE B 1 453 ? -18.723 28.946  -45.379 1.00 18.29  ? 453 PHE B CG     1 
ATOM   14398 C CD1    . PHE B 1 453 ? -19.887 29.667  -45.185 1.00 24.17  ? 453 PHE B CD1    1 
ATOM   14399 C CD2    . PHE B 1 453 ? -18.376 27.975  -44.445 1.00 23.75  ? 453 PHE B CD2    1 
ATOM   14400 C CE1    . PHE B 1 453 ? -20.701 29.422  -44.085 1.00 25.08  ? 453 PHE B CE1    1 
ATOM   14401 C CE2    . PHE B 1 453 ? -19.185 27.728  -43.347 1.00 19.47  ? 453 PHE B CE2    1 
ATOM   14402 C CZ     . PHE B 1 453 ? -20.348 28.447  -43.169 1.00 23.94  ? 453 PHE B CZ     1 
ATOM   14403 H H      . PHE B 1 453 ? -17.377 26.659  -47.366 1.00 23.56  ? 453 PHE B H      1 
ATOM   14404 H HA     . PHE B 1 453 ? -19.072 28.638  -48.108 1.00 23.87  ? 453 PHE B HA     1 
ATOM   14405 H HB2    . PHE B 1 453 ? -16.931 29.026  -46.298 1.00 24.88  ? 453 PHE B HB2    1 
ATOM   14406 H HB3    . PHE B 1 453 ? -17.931 30.159  -46.780 1.00 24.88  ? 453 PHE B HB3    1 
ATOM   14407 H HD1    . PHE B 1 453 ? -20.130 30.321  -45.800 1.00 29.01  ? 453 PHE B HD1    1 
ATOM   14408 H HD2    . PHE B 1 453 ? -17.595 27.484  -44.560 1.00 28.50  ? 453 PHE B HD2    1 
ATOM   14409 H HE1    . PHE B 1 453 ? -21.484 29.910  -43.967 1.00 30.10  ? 453 PHE B HE1    1 
ATOM   14410 H HE2    . PHE B 1 453 ? -18.945 27.073  -42.732 1.00 23.37  ? 453 PHE B HE2    1 
ATOM   14411 H HZ     . PHE B 1 453 ? -20.890 28.282  -42.432 1.00 28.73  ? 453 PHE B HZ     1 
ATOM   14412 N N      . ASP B 1 454 ? -17.323 29.867  -49.506 1.00 19.91  ? 454 ASP B N      1 
ATOM   14413 C CA     . ASP B 1 454 ? -16.230 30.451  -50.276 1.00 23.69  ? 454 ASP B CA     1 
ATOM   14414 C C      . ASP B 1 454 ? -16.267 31.955  -50.038 1.00 21.94  ? 454 ASP B C      1 
ATOM   14415 O O      . ASP B 1 454 ? -17.218 32.488  -49.454 1.00 20.42  ? 454 ASP B O      1 
ATOM   14416 C CB     . ASP B 1 454 ? -16.333 30.118  -51.772 1.00 25.77  ? 454 ASP B CB     1 
ATOM   14417 C CG     . ASP B 1 454 ? -14.973 30.104  -52.474 1.00 26.89  ? 454 ASP B CG     1 
ATOM   14418 O OD1    . ASP B 1 454 ? -13.984 30.615  -51.912 1.00 22.04  ? 454 ASP B OD1    1 
ATOM   14419 O OD2    . ASP B 1 454 ? -14.890 29.584  -53.611 1.00 28.15  ? 454 ASP B OD2    1 
ATOM   14420 H H      . ASP B 1 454 ? -18.035 30.349  -49.483 1.00 23.89  ? 454 ASP B H      1 
ATOM   14421 H HA     . ASP B 1 454 ? -15.386 30.111  -49.940 1.00 28.43  ? 454 ASP B HA     1 
ATOM   14422 H HB2    . ASP B 1 454 ? -16.731 29.239  -51.873 1.00 30.92  ? 454 ASP B HB2    1 
ATOM   14423 H HB3    . ASP B 1 454 ? -16.887 30.785  -52.206 1.00 30.92  ? 454 ASP B HB3    1 
ATOM   14424 N N      . TYR B 1 455 ? -15.211 32.626  -50.462 1.00 20.49  ? 455 TYR B N      1 
ATOM   14425 C CA     . TYR B 1 455 ? -15.050 34.038  -50.177 1.00 17.78  ? 455 TYR B CA     1 
ATOM   14426 C C      . TYR B 1 455 ? -15.944 34.927  -51.025 1.00 23.69  ? 455 TYR B C      1 
ATOM   14427 O O      . TYR B 1 455 ? -16.254 34.622  -52.179 1.00 22.63  ? 455 TYR B O      1 
ATOM   14428 C CB     . TYR B 1 455 ? -13.601 34.440  -50.383 1.00 21.04  ? 455 TYR B CB     1 
ATOM   14429 C CG     . TYR B 1 455 ? -12.710 33.897  -49.310 1.00 26.33  ? 455 TYR B CG     1 
ATOM   14430 C CD1    . TYR B 1 455 ? -12.798 34.384  -48.019 1.00 21.24  ? 455 TYR B CD1    1 
ATOM   14431 C CD2    . TYR B 1 455 ? -11.797 32.881  -49.574 1.00 23.59  ? 455 TYR B CD2    1 
ATOM   14432 C CE1    . TYR B 1 455 ? -11.999 33.894  -47.019 1.00 19.52  ? 455 TYR B CE1    1 
ATOM   14433 C CE2    . TYR B 1 455 ? -10.990 32.382  -48.575 1.00 23.07  ? 455 TYR B CE2    1 
ATOM   14434 C CZ     . TYR B 1 455 ? -11.099 32.890  -47.299 1.00 24.98  ? 455 TYR B CZ     1 
ATOM   14435 O OH     . TYR B 1 455 ? -10.301 32.415  -46.286 1.00 25.57  ? 455 TYR B OH     1 
ATOM   14436 H H      . TYR B 1 455 ? -14.569 32.284  -50.920 1.00 24.59  ? 455 TYR B H      1 
ATOM   14437 H HA     . TYR B 1 455 ? -15.274 34.195  -49.247 1.00 21.34  ? 455 TYR B HA     1 
ATOM   14438 H HB2    . TYR B 1 455 ? -13.293 34.095  -51.235 1.00 25.25  ? 455 TYR B HB2    1 
ATOM   14439 H HB3    . TYR B 1 455 ? -13.534 35.408  -50.371 1.00 25.25  ? 455 TYR B HB3    1 
ATOM   14440 H HD1    . TYR B 1 455 ? -13.407 35.060  -47.827 1.00 25.49  ? 455 TYR B HD1    1 
ATOM   14441 H HD2    . TYR B 1 455 ? -11.727 32.538  -50.436 1.00 28.31  ? 455 TYR B HD2    1 
ATOM   14442 H HE1    . TYR B 1 455 ? -12.067 34.235  -46.156 1.00 23.43  ? 455 TYR B HE1    1 
ATOM   14443 H HE2    . TYR B 1 455 ? -10.379 31.706  -48.760 1.00 27.68  ? 455 TYR B HE2    1 
ATOM   14444 H HH     . TYR B 1 455 ? -10.472 32.822  -45.571 1.00 30.69  ? 455 TYR B HH     1 
ATOM   14445 N N      . VAL B 1 456 ? -16.347 36.038  -50.426 1.00 25.89  ? 456 VAL B N      1 
ATOM   14446 C CA     . VAL B 1 456 ? -17.037 37.095  -51.146 1.00 29.36  ? 456 VAL B CA     1 
ATOM   14447 C C      . VAL B 1 456 ? -15.996 37.932  -51.879 1.00 30.57  ? 456 VAL B C      1 
ATOM   14448 O O      . VAL B 1 456 ? -14.977 38.299  -51.297 1.00 32.72  ? 456 VAL B O      1 
ATOM   14449 C CB     . VAL B 1 456 ? -17.855 37.984  -50.183 1.00 29.38  ? 456 VAL B CB     1 
ATOM   14450 C CG1    . VAL B 1 456 ? -18.562 39.092  -50.942 1.00 44.82  ? 456 VAL B CG1    1 
ATOM   14451 C CG2    . VAL B 1 456 ? -18.857 37.140  -49.410 1.00 27.00  ? 456 VAL B CG2    1 
ATOM   14452 H H      . VAL B 1 456 ? -16.231 36.205  -49.591 1.00 31.07  ? 456 VAL B H      1 
ATOM   14453 H HA     . VAL B 1 456 ? -17.642 36.709  -51.799 1.00 35.23  ? 456 VAL B HA     1 
ATOM   14454 H HB     . VAL B 1 456 ? -17.253 38.395  -49.544 1.00 35.25  ? 456 VAL B HB     1 
ATOM   14455 H HG11   . VAL B 1 456 ? -19.203 39.518  -50.351 1.00 53.78  ? 456 VAL B HG11   1 
ATOM   14456 H HG12   . VAL B 1 456 ? -17.907 39.742  -51.241 1.00 53.78  ? 456 VAL B HG12   1 
ATOM   14457 H HG13   . VAL B 1 456 ? -19.022 38.708  -51.705 1.00 53.78  ? 456 VAL B HG13   1 
ATOM   14458 H HG21   . VAL B 1 456 ? -19.399 37.723  -48.856 1.00 32.40  ? 456 VAL B HG21   1 
ATOM   14459 H HG22   . VAL B 1 456 ? -19.420 36.664  -50.040 1.00 32.40  ? 456 VAL B HG22   1 
ATOM   14460 H HG23   . VAL B 1 456 ? -18.376 36.508  -48.853 1.00 32.40  ? 456 VAL B HG23   1 
ATOM   14461 N N      . HIS B 1 457 ? -16.254 38.227  -53.149 1.00 36.43  ? 457 HIS B N      1 
ATOM   14462 C CA     . HIS B 1 457 ? -15.402 39.121  -53.930 1.00 44.92  ? 457 HIS B CA     1 
ATOM   14463 C C      . HIS B 1 457 ? -16.259 40.243  -54.507 1.00 54.57  ? 457 HIS B C      1 
ATOM   14464 O O      . HIS B 1 457 ? -17.441 40.038  -54.800 1.00 46.93  ? 457 HIS B O      1 
ATOM   14465 C CB     . HIS B 1 457 ? -14.681 38.365  -55.056 1.00 45.97  ? 457 HIS B CB     1 
ATOM   14466 C CG     . HIS B 1 457 ? -13.651 37.390  -54.572 1.00 44.77  ? 457 HIS B CG     1 
ATOM   14467 N ND1    . HIS B 1 457 ? -12.412 37.783  -54.115 1.00 42.56  ? 457 HIS B ND1    1 
ATOM   14468 C CD2    . HIS B 1 457 ? -13.674 36.038  -54.480 1.00 37.39  ? 457 HIS B CD2    1 
ATOM   14469 C CE1    . HIS B 1 457 ? -11.718 36.718  -53.755 1.00 39.55  ? 457 HIS B CE1    1 
ATOM   14470 N NE2    . HIS B 1 457 ? -12.461 35.646  -53.966 1.00 33.00  ? 457 HIS B NE2    1 
ATOM   14471 H H      . HIS B 1 457 ? -16.926 37.918  -53.588 1.00 43.71  ? 457 HIS B H      1 
ATOM   14472 H HA     . HIS B 1 457 ? -14.730 39.523  -53.359 1.00 53.90  ? 457 HIS B HA     1 
ATOM   14473 H HB2    . HIS B 1 457 ? -15.338 37.870  -55.570 1.00 55.17  ? 457 HIS B HB2    1 
ATOM   14474 H HB3    . HIS B 1 457 ? -14.234 39.009  -55.627 1.00 55.17  ? 457 HIS B HB3    1 
ATOM   14475 H HD2    . HIS B 1 457 ? -14.380 35.481  -54.715 1.00 44.86  ? 457 HIS B HD2    1 
ATOM   14476 H HE1    . HIS B 1 457 ? -10.853 36.722  -53.414 1.00 47.46  ? 457 HIS B HE1    1 
ATOM   14477 H HE2    . HIS B 1 457 ? -12.223 34.835  -53.810 1.00 39.60  ? 457 HIS B HE2    1 
ATOM   14478 N N      . HIS B 1 458 ? -15.660 41.421  -54.667 1.00 61.28  ? 458 HIS B N      1 
ATOM   14479 C CA     . HIS B 1 458 ? -16.365 42.584  -55.209 1.00 68.72  ? 458 HIS B CA     1 
ATOM   14480 C C      . HIS B 1 458 ? -15.691 43.113  -56.475 1.00 57.26  ? 458 HIS B C      1 
ATOM   14481 O O      . HIS B 1 458 ? -14.464 43.146  -56.578 1.00 60.32  ? 458 HIS B O      1 
ATOM   14482 C CB     . HIS B 1 458 ? -16.447 43.689  -54.154 1.00 55.31  ? 458 HIS B CB     1 
ATOM   14483 C CG     . HIS B 1 458 ? -17.122 43.264  -52.885 1.00 56.30  ? 458 HIS B CG     1 
ATOM   14484 N ND1    . HIS B 1 458 ? -18.426 42.818  -52.847 1.00 48.29  ? 458 HIS B ND1    1 
ATOM   14485 C CD2    . HIS B 1 458 ? -16.675 43.223  -51.606 1.00 53.99  ? 458 HIS B CD2    1 
ATOM   14486 C CE1    . HIS B 1 458 ? -18.752 42.517  -51.603 1.00 43.21  ? 458 HIS B CE1    1 
ATOM   14487 N NE2    . HIS B 1 458 ? -17.707 42.753  -50.829 1.00 44.63  ? 458 HIS B NE2    1 
ATOM   14488 H H      . HIS B 1 458 ? -14.838 41.575  -54.468 1.00 73.54  ? 458 HIS B H      1 
ATOM   14489 H HA     . HIS B 1 458 ? -17.272 42.336  -55.444 1.00 82.47  ? 458 HIS B HA     1 
ATOM   14490 H HB2    . HIS B 1 458 ? -15.548 43.975  -53.930 1.00 66.37  ? 458 HIS B HB2    1 
ATOM   14491 H HB3    . HIS B 1 458 ? -16.947 44.434  -54.521 1.00 66.37  ? 458 HIS B HB3    1 
ATOM   14492 H HD2    . HIS B 1 458 ? -15.827 43.465  -51.310 1.00 64.79  ? 458 HIS B HD2    1 
ATOM   14493 H HE1    . HIS B 1 458 ? -19.577 42.194  -51.320 1.00 51.85  ? 458 HIS B HE1    1 
ATOM   14494 H HE2    . HIS B 1 458 ? -17.678 42.633  -49.978 1.00 53.56  ? 458 HIS B HE2    1 
HETATM 14495 C C2     . 34D C 2 .   ? -21.419 22.377  -28.047 1.00 27.58  ? 501 34D A C2     1 
HETATM 14496 C C3     . 34D C 2 .   ? -22.486 21.512  -28.219 1.00 30.97  ? 501 34D A C3     1 
HETATM 14497 O O3     . 34D C 2 .   ? -23.796 22.011  -28.281 1.00 33.34  ? 501 34D A O3     1 
HETATM 14498 C C4     . 34D C 2 .   ? -22.263 20.148  -28.332 1.00 35.37  ? 501 34D A C4     1 
HETATM 14499 C C5     . 34D C 2 .   ? -20.971 19.659  -28.268 1.00 34.39  ? 501 34D A C5     1 
HETATM 14500 C C1     . 34D C 2 .   ? -20.127 21.881  -27.987 1.00 26.82  ? 501 34D A C1     1 
HETATM 14501 C C6     . 34D C 2 .   ? -19.901 20.521  -28.097 1.00 27.76  ? 501 34D A C6     1 
HETATM 14502 C C      . 34D C 2 .   ? -18.965 22.824  -27.802 1.00 29.40  ? 501 34D A C      1 
HETATM 14503 O O1     . 34D C 2 .   ? -17.792 22.371  -27.711 1.00 23.47  ? 501 34D A O1     1 
HETATM 14504 O O2     . 34D C 2 .   ? -19.185 24.060  -27.736 1.00 22.58  ? 501 34D A O2     1 
HETATM 14505 O O5     . 34D C 2 .   ? -20.740 18.282  -28.386 1.00 26.43  ? 501 34D A O5     1 
HETATM 14506 H H2     . 34D C 2 .   ? -21.577 23.337  -27.969 1.00 33.09  ? 501 34D A H2     1 
HETATM 14507 H H3     . 34D C 2 .   ? -23.936 22.378  -29.079 1.00 40.01  ? 501 34D A H3     1 
HETATM 14508 H H4     . 34D C 2 .   ? -23.014 19.536  -28.453 1.00 42.44  ? 501 34D A H4     1 
HETATM 14509 H H6     . 34D C 2 .   ? -18.991 20.171  -28.057 1.00 33.32  ? 501 34D A H6     1 
HETATM 14510 H H5     . 34D C 2 .   ? -20.931 17.880  -27.628 1.00 31.72  ? 501 34D A H5     1 
HETATM 14511 C C2     . 34D D 2 .   ? -27.798 -6.841  -19.523 1.00 31.33  ? 502 34D A C2     1 
HETATM 14512 C C3     . 34D D 2 .   ? -28.253 -5.539  -19.386 1.00 33.06  ? 502 34D A C3     1 
HETATM 14513 O O3     . 34D D 2 .   ? -27.338 -4.472  -19.339 1.00 24.48  ? 502 34D A O3     1 
HETATM 14514 C C4     . 34D D 2 .   ? -29.613 -5.283  -19.300 1.00 28.71  ? 502 34D A C4     1 
HETATM 14515 C C5     . 34D D 2 .   ? -30.525 -6.328  -19.348 1.00 33.78  ? 502 34D A C5     1 
HETATM 14516 C C1     . 34D D 2 .   ? -28.716 -7.883  -19.569 1.00 32.24  ? 502 34D A C1     1 
HETATM 14517 C C6     . 34D D 2 .   ? -30.077 -7.634  -19.485 1.00 27.30  ? 502 34D A C6     1 
HETATM 14518 C C      . 34D D 2 .   ? -28.224 -9.300  -19.713 1.00 33.35  ? 502 34D A C      1 
HETATM 14519 O O1     . 34D D 2 .   ? -29.057 -10.235 -19.845 1.00 26.19  ? 502 34D A O1     1 
HETATM 14520 O O2     . 34D D 2 .   ? -26.985 -9.528  -19.700 1.00 27.62  ? 502 34D A O2     1 
HETATM 14521 O O5     . 34D D 2 .   ? -31.899 -6.056  -19.262 1.00 37.06  ? 502 34D A O5     1 
HETATM 14522 H H2     . 34D D 2 .   ? -26.841 -7.025  -19.582 1.00 37.59  ? 502 34D A H2     1 
HETATM 14523 H H3     . 34D D 2 .   ? -27.519 -3.957  -18.638 1.00 29.37  ? 502 34D A H3     1 
HETATM 14524 H H4     . 34D D 2 .   ? -29.930 -4.365  -19.207 1.00 34.45  ? 502 34D A H4     1 
HETATM 14525 H H6     . 34D D 2 .   ? -30.715 -8.372  -19.517 1.00 32.76  ? 502 34D A H6     1 
HETATM 14526 H H5     . 34D D 2 .   ? -32.346 -6.623  -19.780 1.00 44.48  ? 502 34D A H5     1 
HETATM 14527 K K      . K   E 3 .   ? -16.522 -3.814  -20.452 1.00 19.16  ? 503 K   A K      1 
HETATM 14528 K K      . K   F 3 .   ? -11.938 11.999  -26.977 1.00 18.92  ? 501 K   B K      1 
HETATM 14529 O O      . HOH G 4 .   ? -11.423 -11.177 -18.072 1.00 35.03  ? 601 HOH A O      1 
HETATM 14530 O O      . HOH G 4 .   ? -16.749 -11.238 -3.895  1.00 25.07  ? 602 HOH A O      1 
HETATM 14531 O O      . HOH G 4 .   ? -10.448 -16.029 -8.703  1.00 35.53  ? 603 HOH A O      1 
HETATM 14532 O O      . HOH G 4 .   ? -17.084 -9.895  0.068   1.00 35.10  ? 604 HOH A O      1 
HETATM 14533 O O      . HOH G 4 .   ? -14.320 -9.654  -1.713  1.00 39.51  ? 605 HOH A O      1 
HETATM 14534 O O      . HOH G 4 .   ? -21.555 -13.936 6.696   1.00 38.23  ? 606 HOH A O      1 
HETATM 14535 O O      . HOH G 4 .   ? -11.188 -11.663 -11.194 1.00 30.96  ? 607 HOH A O      1 
HETATM 14536 O O      . HOH G 4 .   ? -34.273 -17.774 8.745   1.00 35.14  ? 608 HOH A O      1 
HETATM 14537 O O      . HOH G 4 .   ? -41.577 -7.426  -52.727 1.00 39.25  ? 609 HOH A O      1 
HETATM 14538 O O      . HOH G 4 .   ? -45.081 -20.360 -36.210 1.00 37.75  ? 610 HOH A O      1 
HETATM 14539 O O      . HOH G 4 .   ? -19.078 11.078  -42.376 1.00 40.94  ? 611 HOH A O      1 
HETATM 14540 O O      . HOH G 4 .   ? -36.462 -0.049  -47.970 1.00 39.34  ? 612 HOH A O      1 
HETATM 14541 O O      . HOH G 4 .   ? -11.157 -24.742 -39.101 1.00 36.76  ? 613 HOH A O      1 
HETATM 14542 O O      . HOH G 4 .   ? -9.986  -13.259 -9.152  1.00 31.05  ? 614 HOH A O      1 
HETATM 14543 O O      . HOH G 4 .   ? -33.610 -2.573  -47.956 1.00 41.42  ? 615 HOH A O      1 
HETATM 14544 O O      . HOH G 4 .   ? -25.002 -8.362  -20.665 1.00 31.55  ? 616 HOH A O      1 
HETATM 14545 O O      . HOH G 4 .   ? -27.647 -13.566 -23.525 1.00 36.72  ? 617 HOH A O      1 
HETATM 14546 O O      . HOH G 4 .   ? -29.281 -37.219 -7.464  1.00 47.20  ? 618 HOH A O      1 
HETATM 14547 O O      . HOH G 4 .   ? -27.644 -21.607 -25.909 1.00 27.05  ? 619 HOH A O      1 
HETATM 14548 O O      . HOH G 4 .   ? -21.627 -22.591 -51.055 1.00 23.33  ? 620 HOH A O      1 
HETATM 14549 O O      . HOH G 4 .   ? -16.716 20.384  -26.614 1.00 36.22  ? 621 HOH A O      1 
HETATM 14550 O O      . HOH G 4 .   ? -28.572 -35.115 -22.581 1.00 34.09  ? 622 HOH A O      1 
HETATM 14551 O O      . HOH G 4 .   ? -14.758 5.113   -25.340 1.00 19.63  ? 623 HOH A O      1 
HETATM 14552 O O      . HOH G 4 .   ? -37.141 -20.665 -26.141 1.00 41.64  ? 624 HOH A O      1 
HETATM 14553 O O      . HOH G 4 .   ? -38.778 -6.165  -5.603  1.00 40.77  ? 625 HOH A O      1 
HETATM 14554 O O      . HOH G 4 .   ? -34.618 -11.948 -27.725 1.00 37.60  ? 626 HOH A O      1 
HETATM 14555 O O      . HOH G 4 .   ? -38.015 -18.611 -0.814  1.00 40.25  ? 627 HOH A O      1 
HETATM 14556 O O      . HOH G 4 .   ? -15.296 -20.802 -47.155 1.00 41.05  ? 628 HOH A O      1 
HETATM 14557 O O      . HOH G 4 .   ? -45.645 -3.370  -26.083 1.00 41.06  ? 629 HOH A O      1 
HETATM 14558 O O      . HOH G 4 .   ? -16.349 -24.960 -47.202 1.00 34.29  ? 630 HOH A O      1 
HETATM 14559 O O      . HOH G 4 .   ? -26.311 -25.628 -31.632 1.00 36.00  ? 631 HOH A O      1 
HETATM 14560 O O      . HOH G 4 .   ? -26.889 -23.087 -3.264  1.00 26.31  ? 632 HOH A O      1 
HETATM 14561 O O      . HOH G 4 .   ? -23.328 -34.310 -26.089 1.00 31.07  ? 633 HOH A O      1 
HETATM 14562 O O      . HOH G 4 .   ? -15.885 6.282   -45.929 1.00 37.12  ? 634 HOH A O      1 
HETATM 14563 O O      . HOH G 4 .   ? -43.031 5.999   -38.401 1.00 44.27  ? 635 HOH A O      1 
HETATM 14564 O O      . HOH G 4 .   ? -32.487 3.606   -43.997 1.00 32.00  ? 636 HOH A O      1 
HETATM 14565 O O      . HOH G 4 .   ? -18.944 -8.993  -49.677 1.00 35.19  ? 637 HOH A O      1 
HETATM 14566 O O      . HOH G 4 .   ? -11.659 -13.206 -1.496  1.00 42.80  ? 638 HOH A O      1 
HETATM 14567 O O      . HOH G 4 .   ? -10.161 -14.356 -0.313  1.00 48.58  ? 639 HOH A O      1 
HETATM 14568 O O      . HOH G 4 .   ? -14.548 7.045   -43.865 1.00 28.80  ? 640 HOH A O      1 
HETATM 14569 O O      . HOH G 4 .   ? -6.447  7.808   -26.580 1.00 17.22  ? 641 HOH A O      1 
HETATM 14570 O O      . HOH G 4 .   ? -25.720 -16.207 -30.238 1.00 22.94  ? 642 HOH A O      1 
HETATM 14571 O O      . HOH G 4 .   ? -23.773 -4.296  -22.421 1.00 22.19  ? 643 HOH A O      1 
HETATM 14572 O O      . HOH G 4 .   ? -34.899 -22.169 -27.416 1.00 34.47  ? 644 HOH A O      1 
HETATM 14573 O O      . HOH G 4 .   ? -14.549 -13.336 -48.805 1.00 32.85  ? 645 HOH A O      1 
HETATM 14574 O O      . HOH G 4 .   ? -6.483  -7.141  -36.785 1.00 28.83  ? 646 HOH A O      1 
HETATM 14575 O O      . HOH G 4 .   ? -23.880 24.612  -28.623 1.00 36.33  ? 647 HOH A O      1 
HETATM 14576 O O      . HOH G 4 .   ? -10.862 -23.165 -26.515 1.00 21.64  ? 648 HOH A O      1 
HETATM 14577 O O      . HOH G 4 .   ? -7.707  12.868  -39.771 1.00 18.98  ? 649 HOH A O      1 
HETATM 14578 O O      . HOH G 4 .   ? -38.354 -26.937 -17.214 1.00 36.12  ? 650 HOH A O      1 
HETATM 14579 O O      . HOH G 4 .   ? -24.517 -37.289 -14.821 1.00 41.38  ? 651 HOH A O      1 
HETATM 14580 O O      . HOH G 4 .   ? -9.314  -18.547 -25.849 1.00 38.70  ? 652 HOH A O      1 
HETATM 14581 O O      . HOH G 4 .   ? -9.522  -17.665 -42.944 1.00 37.66  ? 653 HOH A O      1 
HETATM 14582 O O      . HOH G 4 .   ? -42.030 1.364   -41.947 1.00 33.01  ? 654 HOH A O      1 
HETATM 14583 O O      . HOH G 4 .   ? -44.622 -13.951 -27.603 1.00 38.91  ? 655 HOH A O      1 
HETATM 14584 O O      . HOH G 4 .   ? -4.256  6.390   -27.706 1.00 15.42  ? 656 HOH A O      1 
HETATM 14585 O O      . HOH G 4 .   ? -35.704 6.441   -26.205 1.00 41.34  ? 657 HOH A O      1 
HETATM 14586 O O      . HOH G 4 .   ? -36.384 -16.344 -17.671 1.00 34.77  ? 658 HOH A O      1 
HETATM 14587 O O      . HOH G 4 .   ? -16.295 -20.935 4.571   1.00 23.99  ? 659 HOH A O      1 
HETATM 14588 O O      . HOH G 4 .   ? -18.644 -8.026  -45.253 1.00 25.93  ? 660 HOH A O      1 
HETATM 14589 O O      . HOH G 4 .   ? 2.091   -9.133  -30.793 1.00 25.21  ? 661 HOH A O      1 
HETATM 14590 O O      . HOH G 4 .   ? -30.933 -3.142  -7.328  1.00 41.53  ? 662 HOH A O      1 
HETATM 14591 O O      . HOH G 4 .   ? -36.894 -3.467  -11.715 1.00 45.62  ? 663 HOH A O      1 
HETATM 14592 O O      . HOH G 4 .   ? -30.193 -2.057  -3.081  1.00 40.41  ? 664 HOH A O      1 
HETATM 14593 O O      . HOH G 4 .   ? -28.084 -21.715 6.179   1.00 47.02  ? 665 HOH A O      1 
HETATM 14594 O O      . HOH G 4 .   ? -38.303 -18.205 -44.100 1.00 40.63  ? 666 HOH A O      1 
HETATM 14595 O O      . HOH G 4 .   ? 3.028   -10.086 -23.280 1.00 13.71  ? 667 HOH A O      1 
HETATM 14596 O O      . HOH G 4 .   ? -29.690 -32.668 -21.521 1.00 31.11  ? 668 HOH A O      1 
HETATM 14597 O O      . HOH G 4 .   ? -10.355 -10.695 -41.051 1.00 38.57  ? 669 HOH A O      1 
HETATM 14598 O O      . HOH G 4 .   ? -22.200 -19.113 -10.737 1.00 17.64  ? 670 HOH A O      1 
HETATM 14599 O O      . HOH G 4 .   ? -40.739 4.325   -39.527 1.00 41.61  ? 671 HOH A O      1 
HETATM 14600 O O      . HOH G 4 .   ? -34.800 -21.006 -43.371 1.00 32.43  ? 672 HOH A O      1 
HETATM 14601 O O      . HOH G 4 .   ? -17.475 -16.125 -50.621 1.00 20.47  ? 673 HOH A O      1 
HETATM 14602 O O      . HOH G 4 .   ? -7.171  -16.939 -41.511 1.00 40.16  ? 674 HOH A O      1 
HETATM 14603 O O      . HOH G 4 .   ? -14.581 -11.186 -13.451 1.00 19.67  ? 675 HOH A O      1 
HETATM 14604 O O      . HOH G 4 .   ? -13.538 10.922  -28.983 1.00 19.07  ? 676 HOH A O      1 
HETATM 14605 O O      . HOH G 4 .   ? -14.683 -13.908 -44.045 1.00 18.49  ? 677 HOH A O      1 
HETATM 14606 O O      . HOH G 4 .   ? -21.426 -27.571 -42.553 1.00 39.98  ? 678 HOH A O      1 
HETATM 14607 O O      . HOH G 4 .   ? -34.430 -33.756 -12.550 1.00 41.02  ? 679 HOH A O      1 
HETATM 14608 O O      . HOH G 4 .   ? -13.856 -26.317 -40.499 1.00 39.66  ? 680 HOH A O      1 
HETATM 14609 O O      . HOH G 4 .   ? 0.694   -10.745 -34.389 1.00 27.98  ? 681 HOH A O      1 
HETATM 14610 O O      . HOH G 4 .   ? -9.493  -12.870 -36.253 1.00 19.91  ? 682 HOH A O      1 
HETATM 14611 O O      . HOH G 4 .   ? -35.119 0.236   -29.733 1.00 30.66  ? 683 HOH A O      1 
HETATM 14612 O O      . HOH G 4 .   ? -14.577 -12.767 -18.390 1.00 22.82  ? 684 HOH A O      1 
HETATM 14613 O O      . HOH G 4 .   ? -30.115 -4.169  -50.971 1.00 37.71  ? 685 HOH A O      1 
HETATM 14614 O O      . HOH G 4 .   ? -20.407 -9.000  -2.114  1.00 35.59  ? 686 HOH A O      1 
HETATM 14615 O O      . HOH G 4 .   ? -8.139  10.059  -43.462 1.00 40.16  ? 687 HOH A O      1 
HETATM 14616 O O      . HOH G 4 .   ? -18.708 -12.225 -18.039 1.00 16.38  ? 688 HOH A O      1 
HETATM 14617 O O      . HOH G 4 .   ? -35.216 -1.032  -32.305 1.00 34.56  ? 689 HOH A O      1 
HETATM 14618 O O      . HOH G 4 .   ? -17.483 -11.973 -33.157 1.00 21.87  ? 690 HOH A O      1 
HETATM 14619 O O      . HOH G 4 .   ? -33.166 15.157  -35.209 1.00 34.68  ? 691 HOH A O      1 
HETATM 14620 O O      . HOH G 4 .   ? -21.303 7.946   -42.069 1.00 29.80  ? 692 HOH A O      1 
HETATM 14621 O O      . HOH G 4 .   ? -18.640 -11.151 -1.655  1.00 24.63  ? 693 HOH A O      1 
HETATM 14622 O O      . HOH G 4 .   ? -12.276 -8.988  -15.450 1.00 25.13  ? 694 HOH A O      1 
HETATM 14623 O O      . HOH G 4 .   ? -26.578 -38.515 -5.350  1.00 45.22  ? 695 HOH A O      1 
HETATM 14624 O O      . HOH G 4 .   ? -8.859  -28.708 -29.950 1.00 29.50  ? 696 HOH A O      1 
HETATM 14625 O O      . HOH G 4 .   ? -24.227 -24.678 -45.200 1.00 26.31  ? 697 HOH A O      1 
HETATM 14626 O O      . HOH G 4 .   ? -17.692 -4.887  -49.464 1.00 31.26  ? 698 HOH A O      1 
HETATM 14627 O O      . HOH G 4 .   ? -11.384 -22.694 -35.823 1.00 18.03  ? 699 HOH A O      1 
HETATM 14628 O O      . HOH G 4 .   ? -28.461 -22.342 -32.132 1.00 32.29  ? 700 HOH A O      1 
HETATM 14629 O O      . HOH G 4 .   ? -27.153 -13.752 -11.186 1.00 29.78  ? 701 HOH A O      1 
HETATM 14630 O O      . HOH G 4 .   ? -26.767 -16.628 -7.023  1.00 27.81  ? 702 HOH A O      1 
HETATM 14631 O O      . HOH G 4 .   ? -13.865 -27.796 -7.297  1.00 26.13  ? 703 HOH A O      1 
HETATM 14632 O O      . HOH G 4 .   ? -51.450 -1.912  -45.469 1.00 41.43  ? 704 HOH A O      1 
HETATM 14633 O O      . HOH G 4 .   ? -9.809  -10.664 -20.295 1.00 21.34  ? 705 HOH A O      1 
HETATM 14634 O O      . HOH G 4 .   ? -33.997 14.922  -41.939 1.00 39.96  ? 706 HOH A O      1 
HETATM 14635 O O      . HOH G 4 .   ? -13.021 -10.851 -19.523 1.00 28.31  ? 707 HOH A O      1 
HETATM 14636 O O      . HOH G 4 .   ? -23.945 -8.670  -50.512 1.00 29.46  ? 708 HOH A O      1 
HETATM 14637 O O      . HOH G 4 .   ? -19.170 -27.923 -38.123 1.00 29.40  ? 709 HOH A O      1 
HETATM 14638 O O      . HOH G 4 .   ? -33.982 -18.224 -9.130  1.00 27.69  ? 710 HOH A O      1 
HETATM 14639 O O      . HOH G 4 .   ? -2.535  -15.178 -9.671  1.00 33.18  ? 711 HOH A O      1 
HETATM 14640 O O      . HOH G 4 .   ? -24.071 -26.198 -3.034  1.00 40.24  ? 712 HOH A O      1 
HETATM 14641 O O      . HOH G 4 .   ? -4.268  8.156   -34.915 1.00 31.06  ? 713 HOH A O      1 
HETATM 14642 O O      . HOH G 4 .   ? -22.554 -22.970 -30.023 1.00 21.56  ? 714 HOH A O      1 
HETATM 14643 O O      . HOH G 4 .   ? 2.505   -14.280 -27.102 1.00 22.87  ? 715 HOH A O      1 
HETATM 14644 O O      . HOH G 4 .   ? -44.689 1.473   -42.582 1.00 35.45  ? 716 HOH A O      1 
HETATM 14645 O O      . HOH G 4 .   ? -38.736 -9.953  0.513   1.00 43.06  ? 717 HOH A O      1 
HETATM 14646 O O      . HOH G 4 .   ? -12.107 -24.384 -9.556  1.00 31.36  ? 718 HOH A O      1 
HETATM 14647 O O      . HOH G 4 .   ? -27.400 -5.430  -1.421  1.00 35.12  ? 719 HOH A O      1 
HETATM 14648 O O      . HOH G 4 .   ? -17.731 -33.952 -12.561 1.00 33.02  ? 720 HOH A O      1 
HETATM 14649 O O      . HOH G 4 .   ? -32.405 0.883   -47.456 1.00 32.64  ? 721 HOH A O      1 
HETATM 14650 O O      . HOH G 4 .   ? -36.803 -7.913  -32.142 1.00 39.00  ? 722 HOH A O      1 
HETATM 14651 O O      . HOH G 4 .   ? -28.527 18.909  -31.772 1.00 41.53  ? 723 HOH A O      1 
HETATM 14652 O O      . HOH G 4 .   ? -3.427  -1.933  -35.432 1.00 23.91  ? 724 HOH A O      1 
HETATM 14653 O O      . HOH G 4 .   ? -31.289 -30.814 -22.483 1.00 32.93  ? 725 HOH A O      1 
HETATM 14654 O O      . HOH G 4 .   ? -8.019  -25.139 -24.805 1.00 23.07  ? 726 HOH A O      1 
HETATM 14655 O O      . HOH G 4 .   ? -8.087  0.683   -38.668 1.00 37.29  ? 727 HOH A O      1 
HETATM 14656 O O      . HOH G 4 .   ? -21.157 -6.699  -7.732  1.00 29.56  ? 728 HOH A O      1 
HETATM 14657 O O      . HOH G 4 .   ? -16.267 -18.825 -27.520 1.00 16.91  ? 729 HOH A O      1 
HETATM 14658 O O      . HOH G 4 .   ? -5.022  11.946  -29.542 1.00 21.66  ? 730 HOH A O      1 
HETATM 14659 O O      . HOH G 4 .   ? -19.824 -37.901 -15.467 1.00 43.90  ? 731 HOH A O      1 
HETATM 14660 O O      . HOH G 4 .   ? -23.269 -39.405 -23.179 1.00 39.10  ? 732 HOH A O      1 
HETATM 14661 O O      . HOH G 4 .   ? -28.453 -23.567 -23.981 1.00 20.91  ? 733 HOH A O      1 
HETATM 14662 O O      . HOH G 4 .   ? -25.050 -4.935  -47.394 1.00 23.01  ? 734 HOH A O      1 
HETATM 14663 O O      . HOH G 4 .   ? -12.579 -17.598 -30.615 1.00 23.09  ? 735 HOH A O      1 
HETATM 14664 O O      . HOH G 4 .   ? -37.959 -26.976 -9.860  1.00 33.51  ? 736 HOH A O      1 
HETATM 14665 O O      . HOH G 4 .   ? -20.135 -2.435  -49.122 1.00 25.26  ? 737 HOH A O      1 
HETATM 14666 O O      . HOH G 4 .   ? -20.899 25.917  -26.566 1.00 35.17  ? 738 HOH A O      1 
HETATM 14667 O O      . HOH G 4 .   ? -9.352  8.536   -21.007 1.00 17.50  ? 739 HOH A O      1 
HETATM 14668 O O      . HOH G 4 .   ? -19.751 -35.154 -20.123 1.00 31.52  ? 740 HOH A O      1 
HETATM 14669 O O      . HOH G 4 .   ? -14.517 -28.320 -11.769 1.00 22.64  ? 741 HOH A O      1 
HETATM 14670 O O      . HOH G 4 .   ? -23.854 -24.560 -31.669 1.00 23.59  ? 742 HOH A O      1 
HETATM 14671 O O      . HOH G 4 .   ? -41.274 -12.471 -27.166 1.00 38.49  ? 743 HOH A O      1 
HETATM 14672 O O      . HOH G 4 .   ? -3.619  -15.337 -12.272 1.00 30.77  ? 744 HOH A O      1 
HETATM 14673 O O      . HOH G 4 .   ? -22.152 9.205   -44.469 1.00 31.90  ? 745 HOH A O      1 
HETATM 14674 O O      . HOH G 4 .   ? -31.763 -22.959 -33.971 1.00 25.80  ? 746 HOH A O      1 
HETATM 14675 O O      . HOH G 4 .   ? -28.826 -36.600 -10.710 1.00 39.90  ? 747 HOH A O      1 
HETATM 14676 O O      . HOH G 4 .   ? -36.303 -16.785 -49.115 1.00 34.11  ? 748 HOH A O      1 
HETATM 14677 O O      . HOH G 4 .   ? -30.760 -36.437 -18.698 1.00 33.80  ? 749 HOH A O      1 
HETATM 14678 O O      . HOH G 4 .   ? -36.747 -23.622 -17.210 1.00 38.13  ? 750 HOH A O      1 
HETATM 14679 O O      . HOH G 4 .   ? -29.452 -23.245 -36.952 1.00 29.82  ? 751 HOH A O      1 
HETATM 14680 O O      . HOH G 4 .   ? -36.859 -5.953  -9.862  1.00 39.86  ? 752 HOH A O      1 
HETATM 14681 O O      . HOH G 4 .   ? -12.404 -2.295  -26.403 1.00 17.31  ? 753 HOH A O      1 
HETATM 14682 O O      . HOH G 4 .   ? -13.640 -17.652 -24.368 1.00 15.40  ? 754 HOH A O      1 
HETATM 14683 O O      . HOH G 4 .   ? -30.572 -19.374 6.731   1.00 38.64  ? 755 HOH A O      1 
HETATM 14684 O O      . HOH G 4 .   ? -12.016 11.201  -31.241 1.00 16.91  ? 756 HOH A O      1 
HETATM 14685 O O      . HOH G 4 .   ? -30.728 14.837  -45.680 1.00 40.51  ? 757 HOH A O      1 
HETATM 14686 O O      . HOH G 4 .   ? -30.868 -2.497  -48.285 1.00 27.39  ? 758 HOH A O      1 
HETATM 14687 O O      . HOH G 4 .   ? -42.064 -13.023 -48.720 1.00 40.60  ? 759 HOH A O      1 
HETATM 14688 O O      . HOH G 4 .   ? -28.847 -3.164  -30.509 1.00 33.71  ? 760 HOH A O      1 
HETATM 14689 O O      . HOH G 4 .   ? -24.476 -5.846  -8.037  1.00 38.23  ? 761 HOH A O      1 
HETATM 14690 O O      . HOH G 4 .   ? -13.898 -17.256 -28.155 1.00 20.63  ? 762 HOH A O      1 
HETATM 14691 O O      . HOH G 4 .   ? -19.513 -3.316  -20.131 1.00 20.50  ? 763 HOH A O      1 
HETATM 14692 O O      . HOH G 4 .   ? -22.350 -10.812 -50.298 1.00 29.26  ? 764 HOH A O      1 
HETATM 14693 O O      . HOH G 4 .   ? -27.939 -11.472 -30.415 1.00 28.08  ? 765 HOH A O      1 
HETATM 14694 O O      . HOH G 4 .   ? 0.182   6.564   -27.404 1.00 24.02  ? 766 HOH A O      1 
HETATM 14695 O O      . HOH G 4 .   ? -10.184 -28.487 -16.559 1.00 26.47  ? 767 HOH A O      1 
HETATM 14696 O O      . HOH G 4 .   ? -11.510 -19.888 -6.854  1.00 27.10  ? 768 HOH A O      1 
HETATM 14697 O O      . HOH G 4 .   ? -18.823 -35.872 -11.380 1.00 35.01  ? 769 HOH A O      1 
HETATM 14698 O O      . HOH G 4 .   ? -21.660 10.167  -38.061 1.00 23.58  ? 770 HOH A O      1 
HETATM 14699 O O      . HOH G 4 .   ? -8.638  -23.101 -35.366 1.00 24.41  ? 771 HOH A O      1 
HETATM 14700 O O      . HOH G 4 .   ? -35.072 -8.422  -44.059 1.00 31.05  ? 772 HOH A O      1 
HETATM 14701 O O      . HOH G 4 .   ? -7.841  -24.359 -12.094 1.00 31.45  ? 773 HOH A O      1 
HETATM 14702 O O      . HOH G 4 .   ? -34.388 -26.412 0.516   1.00 38.68  ? 774 HOH A O      1 
HETATM 14703 O O      . HOH G 4 .   ? -40.822 -16.700 -2.552  1.00 38.04  ? 775 HOH A O      1 
HETATM 14704 O O      . HOH G 4 .   ? -8.493  -7.320  -14.111 1.00 32.46  ? 776 HOH A O      1 
HETATM 14705 O O      . HOH G 4 .   ? -28.579 7.767   -27.778 1.00 33.84  ? 777 HOH A O      1 
HETATM 14706 O O      . HOH G 4 .   ? -18.733 -10.071 -16.095 1.00 17.63  ? 778 HOH A O      1 
HETATM 14707 O O      . HOH G 4 .   ? -19.128 -24.174 -54.009 1.00 32.88  ? 779 HOH A O      1 
HETATM 14708 O O      . HOH G 4 .   ? -13.588 -0.324  -27.953 1.00 20.88  ? 780 HOH A O      1 
HETATM 14709 O O      . HOH G 4 .   ? -31.813 -10.986 -29.752 1.00 32.47  ? 781 HOH A O      1 
HETATM 14710 O O      . HOH G 4 .   ? -39.464 -6.315  -8.388  1.00 45.84  ? 782 HOH A O      1 
HETATM 14711 O O      . HOH G 4 .   ? -4.450  12.574  -36.798 1.00 32.26  ? 783 HOH A O      1 
HETATM 14712 O O      . HOH G 4 .   ? -33.740 10.579  -47.741 1.00 38.12  ? 784 HOH A O      1 
HETATM 14713 O O      . HOH G 4 .   ? -9.668  -5.692  -22.334 1.00 17.89  ? 785 HOH A O      1 
HETATM 14714 O O      . HOH G 4 .   ? -31.600 8.460   -49.080 1.00 36.31  ? 786 HOH A O      1 
HETATM 14715 O O      . HOH G 4 .   ? -11.682 -16.132 -43.174 1.00 26.05  ? 787 HOH A O      1 
HETATM 14716 O O      . HOH G 4 .   ? -34.258 -28.265 -38.327 1.00 35.42  ? 788 HOH A O      1 
HETATM 14717 O O      . HOH G 4 .   ? -14.969 -17.177 -44.297 1.00 23.93  ? 789 HOH A O      1 
HETATM 14718 O O      . HOH G 4 .   ? -8.901  -13.890 -33.591 1.00 21.17  ? 790 HOH A O      1 
HETATM 14719 O O      . HOH G 4 .   ? -32.882 -2.168  -33.505 1.00 37.52  ? 791 HOH A O      1 
HETATM 14720 O O      . HOH G 4 .   ? -17.319 -34.664 -15.451 1.00 42.46  ? 792 HOH A O      1 
HETATM 14721 O O      . HOH G 4 .   ? -24.412 21.126  -30.985 1.00 34.37  ? 793 HOH A O      1 
HETATM 14722 O O      . HOH G 4 .   ? -4.036  6.959   -39.695 1.00 38.76  ? 794 HOH A O      1 
HETATM 14723 O O      . HOH G 4 .   ? -36.325 -6.006  -28.800 1.00 41.55  ? 795 HOH A O      1 
HETATM 14724 O O      . HOH G 4 .   ? -27.147 -25.424 -1.490  1.00 33.03  ? 796 HOH A O      1 
HETATM 14725 O O      . HOH G 4 .   ? -30.602 -13.903 -21.566 1.00 33.38  ? 797 HOH A O      1 
HETATM 14726 O O      . HOH G 4 .   ? -22.967 -21.554 3.732   1.00 41.59  ? 798 HOH A O      1 
HETATM 14727 O O      . HOH G 4 .   ? -13.634 12.970  -34.472 1.00 17.31  ? 799 HOH A O      1 
HETATM 14728 O O      . HOH G 4 .   ? -12.350 -17.439 -7.642  1.00 26.93  ? 800 HOH A O      1 
HETATM 14729 O O      . HOH G 4 .   ? -42.217 -18.315 -42.045 1.00 42.08  ? 801 HOH A O      1 
HETATM 14730 O O      . HOH G 4 .   ? -34.636 -10.728 -30.259 1.00 36.62  ? 802 HOH A O      1 
HETATM 14731 O O      . HOH G 4 .   ? -15.726 14.550  -38.533 1.00 31.67  ? 803 HOH A O      1 
HETATM 14732 O O      . HOH G 4 .   ? -12.053 -32.129 -32.296 1.00 39.73  ? 804 HOH A O      1 
HETATM 14733 O O      . HOH G 4 .   ? -7.396  -27.286 -34.615 1.00 27.51  ? 805 HOH A O      1 
HETATM 14734 O O      . HOH G 4 .   ? -31.478 -33.683 -19.581 1.00 42.00  ? 806 HOH A O      1 
HETATM 14735 O O      . HOH G 4 .   ? -46.925 -10.255 -29.260 1.00 43.12  ? 807 HOH A O      1 
HETATM 14736 O O      . HOH G 4 .   ? -33.044 -21.469 -45.256 1.00 39.33  ? 808 HOH A O      1 
HETATM 14737 O O      . HOH G 4 .   ? -34.380 -7.240  -30.387 1.00 36.13  ? 809 HOH A O      1 
HETATM 14738 O O      . HOH G 4 .   ? -18.598 -19.806 -53.165 1.00 29.77  ? 810 HOH A O      1 
HETATM 14739 O O      . HOH G 4 .   ? -29.233 -12.272 -9.601  1.00 31.50  ? 811 HOH A O      1 
HETATM 14740 O O      . HOH G 4 .   ? -19.549 8.562   -46.059 1.00 41.16  ? 812 HOH A O      1 
HETATM 14741 O O      . HOH G 4 .   ? -27.250 -28.203 -29.513 1.00 39.66  ? 813 HOH A O      1 
HETATM 14742 O O      . HOH G 4 .   ? -38.168 -15.606 -0.079  1.00 40.69  ? 814 HOH A O      1 
HETATM 14743 O O      . HOH G 4 .   ? -36.165 -31.855 -30.623 1.00 37.82  ? 815 HOH A O      1 
HETATM 14744 O O      . HOH G 4 .   ? -35.069 -33.597 -21.932 1.00 40.33  ? 816 HOH A O      1 
HETATM 14745 O O      . HOH G 4 .   ? -40.541 9.528   -31.535 1.00 35.59  ? 817 HOH A O      1 
HETATM 14746 O O      . HOH G 4 .   ? -28.946 -8.924  -52.090 1.00 45.02  ? 818 HOH A O      1 
HETATM 14747 O O      . HOH G 4 .   ? -36.382 -26.921 -21.030 1.00 44.83  ? 819 HOH A O      1 
HETATM 14748 O O      . HOH G 4 .   ? -40.462 -24.180 -23.433 1.00 35.85  ? 820 HOH A O      1 
HETATM 14749 O O      . HOH G 4 .   ? -28.183 -2.215  -46.864 1.00 28.58  ? 821 HOH A O      1 
HETATM 14750 O O      . HOH G 4 .   ? -10.566 -2.301  -39.839 1.00 27.65  ? 822 HOH A O      1 
HETATM 14751 O O      . HOH G 4 .   ? -10.638 -24.735 -4.571  1.00 41.51  ? 823 HOH A O      1 
HETATM 14752 O O      . HOH G 4 .   ? -39.650 -17.144 -19.588 1.00 40.93  ? 824 HOH A O      1 
HETATM 14753 O O      . HOH G 4 .   ? -8.431  -6.119  -38.397 1.00 25.49  ? 825 HOH A O      1 
HETATM 14754 O O      . HOH G 4 .   ? -17.786 -25.317 -40.140 1.00 35.48  ? 826 HOH A O      1 
HETATM 14755 O O      . HOH G 4 .   ? -10.170 -25.486 -2.156  1.00 42.80  ? 827 HOH A O      1 
HETATM 14756 O O      . HOH G 4 .   ? -27.353 -25.682 -34.036 1.00 35.06  ? 828 HOH A O      1 
HETATM 14757 O O      . HOH G 4 .   ? -25.679 -11.655 -22.678 1.00 35.42  ? 829 HOH A O      1 
HETATM 14758 O O      . HOH G 4 .   ? -22.192 -7.567  -0.658  1.00 38.84  ? 830 HOH A O      1 
HETATM 14759 O O      . HOH G 4 .   ? -10.959 -24.620 1.336   1.00 38.22  ? 831 HOH A O      1 
HETATM 14760 O O      . HOH G 4 .   ? -32.637 -6.225  -50.760 1.00 41.84  ? 832 HOH A O      1 
HETATM 14761 O O      . HOH G 4 .   ? -18.836 -29.125 -33.677 1.00 29.48  ? 833 HOH A O      1 
HETATM 14762 O O      . HOH G 4 .   ? -11.672 7.419   -44.963 1.00 44.91  ? 834 HOH A O      1 
HETATM 14763 O O      . HOH G 4 .   ? -20.963 12.223  -39.800 1.00 29.39  ? 835 HOH A O      1 
HETATM 14764 O O      . HOH G 4 .   ? -24.916 -27.208 -44.630 1.00 39.97  ? 836 HOH A O      1 
HETATM 14765 O O      . HOH G 4 .   ? -42.801 -24.455 -9.100  1.00 42.88  ? 837 HOH A O      1 
HETATM 14766 O O      . HOH G 4 .   ? -21.444 -7.279  1.691   1.00 48.66  ? 838 HOH A O      1 
HETATM 14767 O O      . HOH G 4 .   ? -13.066 -34.021 -34.892 1.00 46.06  ? 839 HOH A O      1 
HETATM 14768 O O      . HOH G 4 .   ? -9.797  -10.998 -12.924 1.00 38.81  ? 840 HOH A O      1 
HETATM 14769 O O      . HOH G 4 .   ? -20.548 -37.941 -19.773 1.00 43.94  ? 841 HOH A O      1 
HETATM 14770 O O      . HOH G 4 .   ? -27.239 -19.698 7.294   1.00 41.38  ? 842 HOH A O      1 
HETATM 14771 O O      . HOH G 4 .   ? -9.693  0.402   -40.051 1.00 36.29  ? 843 HOH A O      1 
HETATM 14772 O O      . HOH G 4 .   ? -6.694  14.893  -29.691 1.00 28.05  ? 844 HOH A O      1 
HETATM 14773 O O      . HOH G 4 .   ? -15.599 -10.665 -16.975 1.00 23.41  ? 845 HOH A O      1 
HETATM 14774 O O      . HOH G 4 .   ? -15.792 -29.911 -9.927  1.00 30.40  ? 846 HOH A O      1 
HETATM 14775 O O      . HOH G 4 .   ? -17.665 -7.412  -47.539 1.00 35.04  ? 847 HOH A O      1 
HETATM 14776 O O      . HOH G 4 .   ? -33.813 3.398   -46.543 1.00 42.25  ? 848 HOH A O      1 
HETATM 14777 O O      . HOH G 4 .   ? -8.200  -30.058 -19.935 1.00 35.80  ? 849 HOH A O      1 
HETATM 14778 O O      . HOH G 4 .   ? -33.326 -30.840 -36.858 1.00 47.54  ? 850 HOH A O      1 
HETATM 14779 O O      . HOH G 4 .   ? -40.282 -14.322 -1.391  1.00 44.37  ? 851 HOH A O      1 
HETATM 14780 O O      . HOH G 4 .   ? -14.422 -19.187 -45.836 1.00 37.20  ? 852 HOH A O      1 
HETATM 14781 O O      . HOH G 4 .   ? -9.953  -20.984 -7.904  1.00 43.95  ? 853 HOH A O      1 
HETATM 14782 O O      . HOH G 4 .   ? -12.295 -29.764 -12.780 1.00 34.58  ? 854 HOH A O      1 
HETATM 14783 O O      . HOH G 4 .   ? -7.364  -11.676 -37.237 1.00 31.39  ? 855 HOH A O      1 
HETATM 14784 O O      . HOH G 4 .   ? -10.527 -7.806  -20.768 1.00 23.07  ? 856 HOH A O      1 
HETATM 14785 O O      . HOH G 4 .   ? -16.469 -23.595 -54.355 1.00 30.73  ? 857 HOH A O      1 
HETATM 14786 O O      . HOH G 4 .   ? -13.192 -26.885 -9.643  1.00 34.36  ? 858 HOH A O      1 
HETATM 14787 O O      . HOH G 4 .   ? -38.632 -20.043 -24.486 1.00 46.99  ? 859 HOH A O      1 
HETATM 14788 O O      . HOH G 4 .   ? -28.872 -23.541 -34.453 1.00 37.91  ? 860 HOH A O      1 
HETATM 14789 O O      . HOH G 4 .   ? -34.970 -22.991 -42.016 1.00 42.66  ? 861 HOH A O      1 
HETATM 14790 O O      . HOH G 4 .   ? -4.757  5.948   -36.926 1.00 37.39  ? 862 HOH A O      1 
HETATM 14791 O O      . HOH G 4 .   ? -8.016  -3.445  -39.385 1.00 32.84  ? 863 HOH A O      1 
HETATM 14792 O O      . HOH G 4 .   ? -25.035 -6.460  -0.488  1.00 37.93  ? 864 HOH A O      1 
HETATM 14793 O O      . HOH G 4 .   ? -8.169  -8.339  -39.773 1.00 36.19  ? 865 HOH A O      1 
HETATM 14794 O O      . HOH G 4 .   ? -19.161 -17.095 -52.633 1.00 28.61  ? 866 HOH A O      1 
HETATM 14795 O O      . HOH G 4 .   ? -0.171  -11.260 -9.467  1.00 43.34  ? 867 HOH A O      1 
HETATM 14796 O O      . HOH G 4 .   ? -49.991 -1.779  -47.873 1.00 44.98  ? 868 HOH A O      1 
HETATM 14797 O O      . HOH G 4 .   ? -15.517 -24.372 -44.293 1.00 42.61  ? 869 HOH A O      1 
HETATM 14798 O O      . HOH G 4 .   ? -18.672 -35.817 -22.350 1.00 39.15  ? 870 HOH A O      1 
HETATM 14799 O O      . HOH G 4 .   ? -25.726 -3.944  -49.765 1.00 34.67  ? 871 HOH A O      1 
HETATM 14800 O O      . HOH G 4 .   ? -20.473 -21.627 -53.340 1.00 28.67  ? 872 HOH A O      1 
HETATM 14801 O O      . HOH G 4 .   ? -39.615 -17.739 -24.278 1.00 49.68  ? 873 HOH A O      1 
HETATM 14802 O O      . HOH G 4 .   ? -9.646  -26.616 -37.670 1.00 46.18  ? 874 HOH A O      1 
HETATM 14803 O O      . HOH G 4 .   ? -18.126 -24.758 -42.397 1.00 43.16  ? 875 HOH A O      1 
HETATM 14804 O O      . HOH G 4 .   ? -35.028 4.737   -42.956 1.00 45.69  ? 876 HOH A O      1 
HETATM 14805 O O      . HOH G 4 .   ? -4.223  -2.713  -37.734 1.00 35.71  ? 877 HOH A O      1 
HETATM 14806 O O      . HOH G 4 .   ? -32.847 -24.446 -43.117 1.00 47.30  ? 878 HOH A O      1 
HETATM 14807 O O      . HOH G 4 .   ? -19.876 16.286  -45.167 1.00 36.88  ? 879 HOH A O      1 
HETATM 14808 O O      . HOH G 4 .   ? -27.092 21.167  -31.895 1.00 42.72  ? 880 HOH A O      1 
HETATM 14809 O O      . HOH G 4 .   ? -6.904  -10.673 -0.303  1.00 45.15  ? 881 HOH A O      1 
HETATM 14810 O O      . HOH H 4 .   ? -8.469  17.489  -47.408 1.00 32.29  ? 601 HOH B O      1 
HETATM 14811 O O      . HOH H 4 .   ? -8.069  20.210  5.497   1.00 36.54  ? 602 HOH B O      1 
HETATM 14812 O O      . HOH H 4 .   ? -26.862 20.160  0.573   1.00 40.26  ? 603 HOH B O      1 
HETATM 14813 O O      . HOH H 4 .   ? -16.217 26.136  -24.077 1.00 31.56  ? 604 HOH B O      1 
HETATM 14814 O O      . HOH H 4 .   ? -10.475 23.123  -53.777 1.00 34.22  ? 605 HOH B O      1 
HETATM 14815 O O      . HOH H 4 .   ? -19.827 -0.108  -3.276  1.00 39.05  ? 606 HOH B O      1 
HETATM 14816 O O      . HOH H 4 .   ? -19.464 33.227  -56.070 1.00 30.40  ? 607 HOH B O      1 
HETATM 14817 O O      . HOH H 4 .   ? -33.319 35.694  -37.051 1.00 41.05  ? 608 HOH B O      1 
HETATM 14818 O O      . HOH H 4 .   ? -2.339  17.324  -46.128 1.00 38.47  ? 609 HOH B O      1 
HETATM 14819 O O      . HOH H 4 .   ? 1.682   17.617  -12.309 1.00 38.64  ? 610 HOH B O      1 
HETATM 14820 O O      . HOH H 4 .   ? -30.288 35.704  -19.632 1.00 41.24  ? 611 HOH B O      1 
HETATM 14821 O O      . HOH H 4 .   ? -3.705  34.691  -4.883  1.00 37.99  ? 612 HOH B O      1 
HETATM 14822 O O      . HOH H 4 .   ? -6.634  35.537  -44.062 1.00 40.18  ? 613 HOH B O      1 
HETATM 14823 O O      . HOH H 4 .   ? -15.273 3.587   -22.163 1.00 20.66  ? 614 HOH B O      1 
HETATM 14824 O O      . HOH H 4 .   ? -12.420 35.379  -10.277 1.00 26.64  ? 615 HOH B O      1 
HETATM 14825 O O      . HOH H 4 .   ? -1.201  16.019  -11.160 1.00 18.39  ? 616 HOH B O      1 
HETATM 14826 O O      . HOH H 4 .   ? -17.722 16.222  -25.070 1.00 21.17  ? 617 HOH B O      1 
HETATM 14827 O O      . HOH H 4 .   ? -31.235 19.536  0.290   1.00 36.34  ? 618 HOH B O      1 
HETATM 14828 O O      . HOH H 4 .   ? -29.332 19.670  -15.154 1.00 31.39  ? 619 HOH B O      1 
HETATM 14829 O O      . HOH H 4 .   ? -1.874  41.607  -21.201 1.00 30.78  ? 620 HOH B O      1 
HETATM 14830 O O      . HOH H 4 .   ? -1.036  16.641  -38.131 1.00 35.78  ? 621 HOH B O      1 
HETATM 14831 O O      . HOH H 4 .   ? 3.643   26.697  -8.009  1.00 32.12  ? 622 HOH B O      1 
HETATM 14832 O O      . HOH H 4 .   ? -9.110  41.199  -18.302 1.00 39.28  ? 623 HOH B O      1 
HETATM 14833 O O      . HOH H 4 .   ? -11.360 29.549  -52.606 1.00 26.34  ? 624 HOH B O      1 
HETATM 14834 O O      . HOH H 4 .   ? -27.109 41.125  -11.448 1.00 35.03  ? 625 HOH B O      1 
HETATM 14835 O O      . HOH H 4 .   ? -8.117  18.545  -43.502 1.00 21.36  ? 626 HOH B O      1 
HETATM 14836 O O      . HOH H 4 .   ? -5.400  18.576  -29.178 1.00 23.42  ? 627 HOH B O      1 
HETATM 14837 O O      . HOH H 4 .   ? -12.330 -4.513  -3.919  1.00 39.40  ? 628 HOH B O      1 
HETATM 14838 O O      . HOH H 4 .   ? -21.224 40.815  -48.666 1.00 36.58  ? 629 HOH B O      1 
HETATM 14839 O O      . HOH H 4 .   ? -30.869 41.630  -9.771  1.00 41.86  ? 630 HOH B O      1 
HETATM 14840 O O      . HOH H 4 .   ? -23.513 41.935  -45.378 1.00 37.63  ? 631 HOH B O      1 
HETATM 14841 O O      . HOH H 4 .   ? -18.473 36.266  -4.088  1.00 28.32  ? 632 HOH B O      1 
HETATM 14842 O O      . HOH H 4 .   ? -13.218 27.399  -17.260 1.00 22.09  ? 633 HOH B O      1 
HETATM 14843 O O      . HOH H 4 .   ? -1.397  33.679  -9.162  1.00 31.82  ? 634 HOH B O      1 
HETATM 14844 O O      . HOH H 4 .   ? -22.163 36.030  -46.735 1.00 28.51  ? 635 HOH B O      1 
HETATM 14845 O O      . HOH H 4 .   ? -5.509  19.084  1.612   1.00 34.16  ? 636 HOH B O      1 
HETATM 14846 O O      . HOH H 4 .   ? -34.284 -0.735  -15.529 1.00 42.59  ? 637 HOH B O      1 
HETATM 14847 O O      . HOH H 4 .   ? -23.986 3.950   -3.167  1.00 30.15  ? 638 HOH B O      1 
HETATM 14848 O O      . HOH H 4 .   ? -31.410 28.485  5.222   1.00 39.33  ? 639 HOH B O      1 
HETATM 14849 O O      . HOH H 4 .   ? 6.278   8.705   -13.030 1.00 27.09  ? 640 HOH B O      1 
HETATM 14850 O O      . HOH H 4 .   ? -13.062 15.933  -42.439 1.00 32.88  ? 641 HOH B O      1 
HETATM 14851 O O      . HOH H 4 .   ? -22.547 4.608   -5.263  1.00 31.49  ? 642 HOH B O      1 
HETATM 14852 O O      . HOH H 4 .   ? -24.720 43.225  -18.421 1.00 41.47  ? 643 HOH B O      1 
HETATM 14853 O O      . HOH H 4 .   ? -11.930 33.043  -21.507 1.00 22.02  ? 644 HOH B O      1 
HETATM 14854 O O      . HOH H 4 .   ? -12.765 13.633  1.962   1.00 30.35  ? 645 HOH B O      1 
HETATM 14855 O O      . HOH H 4 .   ? -5.436  14.101  -31.927 1.00 23.64  ? 646 HOH B O      1 
HETATM 14856 O O      . HOH H 4 .   ? -6.218  22.814  3.146   1.00 21.83  ? 647 HOH B O      1 
HETATM 14857 O O      . HOH H 4 .   ? 3.089   25.319  -20.849 1.00 20.71  ? 648 HOH B O      1 
HETATM 14858 O O      . HOH H 4 .   ? -3.310  30.633  6.572   1.00 27.10  ? 649 HOH B O      1 
HETATM 14859 O O      . HOH H 4 .   ? -22.338 0.800   -5.282  1.00 36.90  ? 650 HOH B O      1 
HETATM 14860 O O      . HOH H 4 .   ? -7.083  -3.149  -19.663 1.00 15.19  ? 651 HOH B O      1 
HETATM 14861 O O      . HOH H 4 .   ? -4.919  46.221  -36.520 1.00 33.07  ? 652 HOH B O      1 
HETATM 14862 O O      . HOH H 4 .   ? -8.328  19.369  -14.329 1.00 21.19  ? 653 HOH B O      1 
HETATM 14863 O O      . HOH H 4 .   ? -11.629 16.706  -2.251  1.00 22.73  ? 654 HOH B O      1 
HETATM 14864 O O      . HOH H 4 .   ? -12.128 33.073  -53.348 1.00 33.00  ? 655 HOH B O      1 
HETATM 14865 O O      . HOH H 4 .   ? -10.457 34.058  -44.108 1.00 21.25  ? 656 HOH B O      1 
HETATM 14866 O O      . HOH H 4 .   ? -7.510  17.385  2.819   1.00 37.36  ? 657 HOH B O      1 
HETATM 14867 O O      . HOH H 4 .   ? -24.357 18.769  -40.530 1.00 33.25  ? 658 HOH B O      1 
HETATM 14868 O O      . HOH H 4 .   ? -22.749 28.348  -19.776 1.00 34.33  ? 659 HOH B O      1 
HETATM 14869 O O      . HOH H 4 .   ? -6.862  31.381  -17.428 1.00 19.63  ? 660 HOH B O      1 
HETATM 14870 O O      . HOH H 4 .   ? 2.798   38.372  -34.836 1.00 32.56  ? 661 HOH B O      1 
HETATM 14871 O O      . HOH H 4 .   ? -6.291  17.124  -34.009 1.00 19.09  ? 662 HOH B O      1 
HETATM 14872 O O      . HOH H 4 .   ? -8.120  -4.882  -12.761 1.00 28.80  ? 663 HOH B O      1 
HETATM 14873 O O      . HOH H 4 .   ? -4.984  19.627  -3.357  1.00 16.45  ? 664 HOH B O      1 
HETATM 14874 O O      . HOH H 4 .   ? -29.517 21.932  -36.076 1.00 40.50  ? 665 HOH B O      1 
HETATM 14875 O O      . HOH H 4 .   ? -12.439 14.725  -27.710 1.00 18.70  ? 666 HOH B O      1 
HETATM 14876 O O      . HOH H 4 .   ? -14.115 16.868  -39.741 1.00 30.65  ? 667 HOH B O      1 
HETATM 14877 O O      . HOH H 4 .   ? -0.880  29.690  -0.381  1.00 31.00  ? 668 HOH B O      1 
HETATM 14878 O O      . HOH H 4 .   ? -28.133 16.606  -0.293  1.00 31.63  ? 669 HOH B O      1 
HETATM 14879 O O      . HOH H 4 .   ? -19.218 33.332  -38.417 1.00 23.26  ? 670 HOH B O      1 
HETATM 14880 O O      . HOH H 4 .   ? 1.573   40.687  -27.162 1.00 30.25  ? 671 HOH B O      1 
HETATM 14881 O O      . HOH H 4 .   ? -5.070  39.712  -41.945 1.00 34.58  ? 672 HOH B O      1 
HETATM 14882 O O      . HOH H 4 .   ? -16.660 3.184   -1.487  1.00 32.80  ? 673 HOH B O      1 
HETATM 14883 O O      . HOH H 4 .   ? -8.076  43.412  -25.719 1.00 33.21  ? 674 HOH B O      1 
HETATM 14884 O O      . HOH H 4 .   ? 2.386   25.163  -11.484 1.00 19.16  ? 675 HOH B O      1 
HETATM 14885 O O      . HOH H 4 .   ? -13.702 28.164  -40.480 1.00 20.02  ? 676 HOH B O      1 
HETATM 14886 O O      . HOH H 4 .   ? 7.964   6.938   -24.160 1.00 13.30  ? 677 HOH B O      1 
HETATM 14887 O O      . HOH H 4 .   ? -10.622 -7.394  -17.845 1.00 19.58  ? 678 HOH B O      1 
HETATM 14888 O O      . HOH H 4 .   ? -24.240 17.637  -44.568 1.00 31.80  ? 679 HOH B O      1 
HETATM 14889 O O      . HOH H 4 .   ? -35.111 39.910  -5.006  1.00 43.02  ? 680 HOH B O      1 
HETATM 14890 O O      . HOH H 4 .   ? -18.056 37.339  -19.853 1.00 37.15  ? 681 HOH B O      1 
HETATM 14891 O O      . HOH H 4 .   ? -27.966 32.658  -20.348 1.00 36.91  ? 682 HOH B O      1 
HETATM 14892 O O      . HOH H 4 .   ? -8.533  27.984  -36.658 1.00 15.01  ? 683 HOH B O      1 
HETATM 14893 O O      . HOH H 4 .   ? -9.260  20.295  -29.449 1.00 16.18  ? 684 HOH B O      1 
HETATM 14894 O O      . HOH H 4 .   ? -14.570 36.375  -13.408 1.00 22.12  ? 685 HOH B O      1 
HETATM 14895 O O      . HOH H 4 .   ? -7.036  47.234  -30.434 1.00 33.97  ? 686 HOH B O      1 
HETATM 14896 O O      . HOH H 4 .   ? -24.661 31.825  -50.764 1.00 35.69  ? 687 HOH B O      1 
HETATM 14897 O O      . HOH H 4 .   ? -13.663 -6.674  -7.655  1.00 18.80  ? 688 HOH B O      1 
HETATM 14898 O O      . HOH H 4 .   ? -1.192  21.578  -16.846 1.00 22.01  ? 689 HOH B O      1 
HETATM 14899 O O      . HOH H 4 .   ? -36.789 27.057  -21.446 1.00 35.30  ? 690 HOH B O      1 
HETATM 14900 O O      . HOH H 4 .   ? -8.250  22.742  -52.197 1.00 28.60  ? 691 HOH B O      1 
HETATM 14901 O O      . HOH H 4 .   ? -29.519 25.458  -42.097 1.00 29.99  ? 692 HOH B O      1 
HETATM 14902 O O      . HOH H 4 .   ? -10.897 3.196   -23.689 1.00 20.79  ? 693 HOH B O      1 
HETATM 14903 O O      . HOH H 4 .   ? -18.447 -5.738  -19.690 1.00 21.25  ? 694 HOH B O      1 
HETATM 14904 O O      . HOH H 4 .   ? -29.585 14.219  -3.477  1.00 29.74  ? 695 HOH B O      1 
HETATM 14905 O O      . HOH H 4 .   ? -1.693  9.490   -10.510 1.00 34.66  ? 696 HOH B O      1 
HETATM 14906 O O      . HOH H 4 .   ? -22.682 32.731  -30.181 1.00 28.52  ? 697 HOH B O      1 
HETATM 14907 O O      . HOH H 4 .   ? 2.858   27.024  -37.929 1.00 29.57  ? 698 HOH B O      1 
HETATM 14908 O O      . HOH H 4 .   ? -3.740  24.570  -19.904 1.00 18.32  ? 699 HOH B O      1 
HETATM 14909 O O      . HOH H 4 .   ? -22.890 18.213  -16.822 1.00 32.25  ? 700 HOH B O      1 
HETATM 14910 O O      . HOH H 4 .   ? -25.625 40.401  -33.903 1.00 41.54  ? 701 HOH B O      1 
HETATM 14911 O O      . HOH H 4 .   ? 3.192   30.962  -40.129 1.00 26.18  ? 702 HOH B O      1 
HETATM 14912 O O      . HOH H 4 .   ? -17.440 -2.064  -18.526 1.00 19.16  ? 703 HOH B O      1 
HETATM 14913 O O      . HOH H 4 .   ? -11.599 17.755  2.246   1.00 35.11  ? 704 HOH B O      1 
HETATM 14914 O O      . HOH H 4 .   ? -18.004 43.110  -37.666 1.00 31.68  ? 705 HOH B O      1 
HETATM 14915 O O      . HOH H 4 .   ? -15.184 42.485  -27.211 1.00 37.85  ? 706 HOH B O      1 
HETATM 14916 O O      . HOH H 4 .   ? -7.366  33.748  -2.080  1.00 24.50  ? 707 HOH B O      1 
HETATM 14917 O O      . HOH H 4 .   ? -15.624 25.992  -36.453 1.00 25.45  ? 708 HOH B O      1 
HETATM 14918 O O      . HOH H 4 .   ? -17.321 17.696  -39.442 1.00 32.27  ? 709 HOH B O      1 
HETATM 14919 O O      . HOH H 4 .   ? -9.550  -3.233  -20.811 1.00 14.09  ? 710 HOH B O      1 
HETATM 14920 O O      . HOH H 4 .   ? -15.781 33.586  1.080   1.00 34.46  ? 711 HOH B O      1 
HETATM 14921 O O      . HOH H 4 .   ? -5.035  15.960  -27.846 1.00 26.45  ? 712 HOH B O      1 
HETATM 14922 O O      . HOH H 4 .   ? -20.742 42.072  -24.132 1.00 36.53  ? 713 HOH B O      1 
HETATM 14923 O O      . HOH H 4 .   ? 4.839   24.204  -12.073 1.00 23.80  ? 714 HOH B O      1 
HETATM 14924 O O      . HOH H 4 .   ? -25.794 40.949  -37.382 1.00 33.22  ? 715 HOH B O      1 
HETATM 14925 O O      . HOH H 4 .   ? -28.486 8.724   -19.878 1.00 33.37  ? 716 HOH B O      1 
HETATM 14926 O O      . HOH H 4 .   ? -1.836  3.411   -11.975 1.00 22.27  ? 717 HOH B O      1 
HETATM 14927 O O      . HOH H 4 .   ? -19.049 42.348  -30.275 1.00 36.90  ? 718 HOH B O      1 
HETATM 14928 O O      . HOH H 4 .   ? -29.800 18.557  -17.795 1.00 27.82  ? 719 HOH B O      1 
HETATM 14929 O O      . HOH H 4 .   ? -13.144 21.098  2.841   1.00 26.01  ? 720 HOH B O      1 
HETATM 14930 O O      . HOH H 4 .   ? -3.431  -5.642  -19.906 1.00 22.94  ? 721 HOH B O      1 
HETATM 14931 O O      . HOH H 4 .   ? -9.626  19.220  -45.825 1.00 24.23  ? 722 HOH B O      1 
HETATM 14932 O O      . HOH H 4 .   ? -19.830 18.964  -46.309 1.00 32.29  ? 723 HOH B O      1 
HETATM 14933 O O      . HOH H 4 .   ? -2.438  26.367  -52.059 1.00 23.71  ? 724 HOH B O      1 
HETATM 14934 O O      . HOH H 4 .   ? 6.648   6.585   -16.442 1.00 25.08  ? 725 HOH B O      1 
HETATM 14935 O O      . HOH H 4 .   ? -2.168  22.270  -23.076 1.00 16.27  ? 726 HOH B O      1 
HETATM 14936 O O      . HOH H 4 .   ? -42.641 29.405  -2.303  1.00 40.86  ? 727 HOH B O      1 
HETATM 14937 O O      . HOH H 4 .   ? 2.791   31.767  -35.583 1.00 23.98  ? 728 HOH B O      1 
HETATM 14938 O O      . HOH H 4 .   ? -5.198  9.922   -25.006 1.00 15.60  ? 729 HOH B O      1 
HETATM 14939 O O      . HOH H 4 .   ? -6.265  30.518  3.710   1.00 20.28  ? 730 HOH B O      1 
HETATM 14940 O O      . HOH H 4 .   ? -7.089  33.421  -15.742 1.00 25.59  ? 731 HOH B O      1 
HETATM 14941 O O      . HOH H 4 .   ? -7.950  30.591  -51.017 1.00 29.82  ? 732 HOH B O      1 
HETATM 14942 O O      . HOH H 4 .   ? -34.414 3.870   -2.111  1.00 42.96  ? 733 HOH B O      1 
HETATM 14943 O O      . HOH H 4 .   ? -16.209 -3.171  -16.199 1.00 18.34  ? 734 HOH B O      1 
HETATM 14944 O O      . HOH H 4 .   ? -33.686 13.739  -21.621 1.00 39.38  ? 735 HOH B O      1 
HETATM 14945 O O      . HOH H 4 .   ? -18.608 17.478  -0.019  1.00 21.73  ? 736 HOH B O      1 
HETATM 14946 O O      . HOH H 4 .   ? -36.473 21.378  -5.602  1.00 35.29  ? 737 HOH B O      1 
HETATM 14947 O O      . HOH H 4 .   ? -1.737  30.782  -7.497  1.00 35.07  ? 738 HOH B O      1 
HETATM 14948 O O      . HOH H 4 .   ? -1.169  21.535  -39.685 1.00 24.70  ? 739 HOH B O      1 
HETATM 14949 O O      . HOH H 4 .   ? -11.508 35.048  -23.445 1.00 18.96  ? 740 HOH B O      1 
HETATM 14950 O O      . HOH H 4 .   ? -21.940 33.566  1.583   1.00 27.63  ? 741 HOH B O      1 
HETATM 14951 O O      . HOH H 4 .   ? -23.874 25.696  -25.190 1.00 38.32  ? 742 HOH B O      1 
HETATM 14952 O O      . HOH H 4 .   ? -22.991 35.749  -3.499  1.00 35.43  ? 743 HOH B O      1 
HETATM 14953 O O      . HOH H 4 .   ? -16.118 47.691  -44.896 1.00 36.69  ? 744 HOH B O      1 
HETATM 14954 O O      . HOH H 4 .   ? -0.619  36.666  -15.738 1.00 40.09  ? 745 HOH B O      1 
HETATM 14955 O O      . HOH H 4 .   ? -1.126  44.387  -32.511 1.00 38.78  ? 746 HOH B O      1 
HETATM 14956 O O      . HOH H 4 .   ? -12.119 18.314  -45.493 1.00 27.96  ? 747 HOH B O      1 
HETATM 14957 O O      . HOH H 4 .   ? 3.049   40.659  -35.911 1.00 37.42  ? 748 HOH B O      1 
HETATM 14958 O O      . HOH H 4 .   ? -25.131 18.520  0.710   1.00 31.49  ? 749 HOH B O      1 
HETATM 14959 O O      . HOH H 4 .   ? -10.400 18.444  -31.372 1.00 19.04  ? 750 HOH B O      1 
HETATM 14960 O O      . HOH H 4 .   ? -25.250 25.885  -3.512  1.00 27.39  ? 751 HOH B O      1 
HETATM 14961 O O      . HOH H 4 .   ? -15.562 32.771  -54.193 1.00 28.91  ? 752 HOH B O      1 
HETATM 14962 O O      . HOH H 4 .   ? -4.855  47.353  -39.534 1.00 44.29  ? 753 HOH B O      1 
HETATM 14963 O O      . HOH H 4 .   ? -38.327 35.036  -2.235  1.00 42.74  ? 754 HOH B O      1 
HETATM 14964 O O      . HOH H 4 .   ? -2.614  15.854  -36.177 1.00 29.62  ? 755 HOH B O      1 
HETATM 14965 O O      . HOH H 4 .   ? 6.405   25.597  -22.467 1.00 22.98  ? 756 HOH B O      1 
HETATM 14966 O O      . HOH H 4 .   ? -21.151 26.324  -17.843 1.00 31.03  ? 757 HOH B O      1 
HETATM 14967 O O      . HOH H 4 .   ? -10.467 42.726  -25.053 1.00 33.37  ? 758 HOH B O      1 
HETATM 14968 O O      . HOH H 4 .   ? -15.805 20.217  3.044   1.00 27.15  ? 759 HOH B O      1 
HETATM 14969 O O      . HOH H 4 .   ? 1.009   22.963  -40.466 1.00 25.44  ? 760 HOH B O      1 
HETATM 14970 O O      . HOH H 4 .   ? -24.027 3.015   -9.444  1.00 24.82  ? 761 HOH B O      1 
HETATM 14971 O O      . HOH H 4 .   ? -2.504  22.062  -19.316 1.00 20.65  ? 762 HOH B O      1 
HETATM 14972 O O      . HOH H 4 .   ? 4.872   27.136  -45.194 1.00 42.75  ? 763 HOH B O      1 
HETATM 14973 O O      . HOH H 4 .   ? -12.078 34.026  -15.366 1.00 30.53  ? 764 HOH B O      1 
HETATM 14974 O O      . HOH H 4 .   ? -26.194 37.971  -5.323  1.00 39.94  ? 765 HOH B O      1 
HETATM 14975 O O      . HOH H 4 .   ? -30.473 23.593  -25.697 1.00 38.15  ? 766 HOH B O      1 
HETATM 14976 O O      . HOH H 4 .   ? -8.381  35.835  -15.670 1.00 37.80  ? 767 HOH B O      1 
HETATM 14977 O O      . HOH H 4 .   ? -3.687  22.529  -3.169  1.00 23.48  ? 768 HOH B O      1 
HETATM 14978 O O      . HOH H 4 .   ? -18.239 44.440  -45.677 1.00 34.46  ? 769 HOH B O      1 
HETATM 14979 O O      . HOH H 4 .   ? -24.383 0.851   -7.804  1.00 32.96  ? 770 HOH B O      1 
HETATM 14980 O O      . HOH H 4 .   ? -15.863 12.724  1.617   1.00 27.16  ? 771 HOH B O      1 
HETATM 14981 O O      . HOH H 4 .   ? -34.075 33.599  -18.483 1.00 37.12  ? 772 HOH B O      1 
HETATM 14982 O O      . HOH H 4 .   ? -18.847 38.899  -30.060 1.00 33.95  ? 773 HOH B O      1 
HETATM 14983 O O      . HOH H 4 .   ? 6.540   29.585  -30.868 1.00 28.35  ? 774 HOH B O      1 
HETATM 14984 O O      . HOH H 4 .   ? -40.141 22.498  -21.630 1.00 42.98  ? 775 HOH B O      1 
HETATM 14985 O O      . HOH H 4 .   ? -28.970 33.552  0.992   1.00 39.25  ? 776 HOH B O      1 
HETATM 14986 O O      . HOH H 4 .   ? -38.751 22.759  -4.946  1.00 35.17  ? 777 HOH B O      1 
HETATM 14987 O O      . HOH H 4 .   ? -27.245 28.764  -48.216 1.00 33.07  ? 778 HOH B O      1 
HETATM 14988 O O      . HOH H 4 .   ? -23.461 30.649  -31.650 1.00 36.71  ? 779 HOH B O      1 
HETATM 14989 O O      . HOH H 4 .   ? -18.582 -3.641  -12.965 1.00 17.46  ? 780 HOH B O      1 
HETATM 14990 O O      . HOH H 4 .   ? -17.980 25.760  -37.953 1.00 27.05  ? 781 HOH B O      1 
HETATM 14991 O O      . HOH H 4 .   ? 7.743   28.987  -17.600 1.00 31.86  ? 782 HOH B O      1 
HETATM 14992 O O      . HOH H 4 .   ? -12.305 45.598  -21.694 1.00 46.61  ? 783 HOH B O      1 
HETATM 14993 O O      . HOH H 4 .   ? -24.637 35.231  -28.034 1.00 41.63  ? 784 HOH B O      1 
HETATM 14994 O O      . HOH H 4 .   ? -31.723 31.958  -23.623 1.00 47.11  ? 785 HOH B O      1 
HETATM 14995 O O      . HOH H 4 .   ? -29.161 10.130  2.188   1.00 45.84  ? 786 HOH B O      1 
HETATM 14996 O O      . HOH H 4 .   ? -10.354 -8.106  -10.734 1.00 29.51  ? 787 HOH B O      1 
HETATM 14997 O O      . HOH H 4 .   ? -35.376 37.809  -39.880 1.00 51.75  ? 788 HOH B O      1 
HETATM 14998 O O      . HOH H 4 .   ? -8.978  32.265  6.076   1.00 37.86  ? 789 HOH B O      1 
HETATM 14999 O O      . HOH H 4 .   ? -15.378 23.442  -24.664 1.00 32.55  ? 790 HOH B O      1 
HETATM 15000 O O      . HOH H 4 .   ? -34.895 10.349  -21.193 1.00 44.57  ? 791 HOH B O      1 
HETATM 15001 O O      . HOH H 4 .   ? -15.991 1.787   -3.563  1.00 30.76  ? 792 HOH B O      1 
HETATM 15002 O O      . HOH H 4 .   ? -11.316 7.499   -19.566 1.00 20.72  ? 793 HOH B O      1 
HETATM 15003 O O      . HOH H 4 .   ? -7.946  38.153  -17.722 1.00 38.09  ? 794 HOH B O      1 
HETATM 15004 O O      . HOH H 4 .   ? -22.566 42.933  -38.009 1.00 35.58  ? 795 HOH B O      1 
HETATM 15005 O O      . HOH H 4 .   ? -24.078 37.724  -7.494  1.00 41.37  ? 796 HOH B O      1 
HETATM 15006 O O      . HOH H 4 .   ? -14.679 13.230  -27.487 1.00 21.64  ? 797 HOH B O      1 
HETATM 15007 O O      . HOH H 4 .   ? -31.275 9.631   1.578   1.00 39.24  ? 798 HOH B O      1 
HETATM 15008 O O      . HOH H 4 .   ? -27.266 25.107  -35.301 1.00 41.37  ? 799 HOH B O      1 
HETATM 15009 O O      . HOH H 4 .   ? -23.651 42.398  -35.485 1.00 38.23  ? 800 HOH B O      1 
HETATM 15010 O O      . HOH H 4 .   ? -14.955 40.603  -48.107 1.00 29.58  ? 801 HOH B O      1 
HETATM 15011 O O      . HOH H 4 .   ? -1.346  15.504  -43.017 1.00 38.11  ? 802 HOH B O      1 
HETATM 15012 O O      . HOH H 4 .   ? -5.327  12.545  -3.278  1.00 40.93  ? 803 HOH B O      1 
HETATM 15013 O O      . HOH H 4 .   ? -13.765 33.089  2.850   1.00 35.11  ? 804 HOH B O      1 
HETATM 15014 O O      . HOH H 4 .   ? -5.165  26.593  5.749   1.00 25.23  ? 805 HOH B O      1 
HETATM 15015 O O      . HOH H 4 .   ? 3.716   25.319  -5.665  1.00 41.21  ? 806 HOH B O      1 
HETATM 15016 O O      . HOH H 4 .   ? -13.241 46.026  -17.271 1.00 38.26  ? 807 HOH B O      1 
HETATM 15017 O O      . HOH H 4 .   ? -22.677 30.219  -53.442 1.00 34.37  ? 808 HOH B O      1 
HETATM 15018 O O      . HOH H 4 .   ? 3.391   38.582  -31.902 1.00 33.96  ? 809 HOH B O      1 
HETATM 15019 O O      . HOH H 4 .   ? -27.453 36.153  -28.501 1.00 41.96  ? 810 HOH B O      1 
HETATM 15020 O O      . HOH H 4 .   ? -26.794 24.463  -50.062 1.00 30.85  ? 811 HOH B O      1 
HETATM 15021 O O      . HOH H 4 .   ? -13.873 42.225  -9.268  1.00 32.44  ? 812 HOH B O      1 
HETATM 15022 O O      . HOH H 4 .   ? 6.349   24.913  -35.354 1.00 35.36  ? 813 HOH B O      1 
HETATM 15023 O O      . HOH H 4 .   ? -25.079 24.549  -17.318 1.00 33.53  ? 814 HOH B O      1 
HETATM 15024 O O      . HOH H 4 .   ? -22.015 22.239  3.839   1.00 40.92  ? 815 HOH B O      1 
HETATM 15025 O O      . HOH H 4 .   ? -21.635 38.125  -6.767  1.00 38.00  ? 816 HOH B O      1 
HETATM 15026 O O      . HOH H 4 .   ? -25.786 35.881  -44.934 1.00 38.11  ? 817 HOH B O      1 
HETATM 15027 O O      . HOH H 4 .   ? -9.528  36.096  -45.764 1.00 20.81  ? 818 HOH B O      1 
HETATM 15028 O O      . HOH H 4 .   ? -39.229 13.469  -16.225 1.00 39.40  ? 819 HOH B O      1 
HETATM 15029 O O      . HOH H 4 .   ? -1.418  19.881  -4.136  1.00 22.66  ? 820 HOH B O      1 
HETATM 15030 O O      . HOH H 4 .   ? 3.898   26.746  -48.775 1.00 34.55  ? 821 HOH B O      1 
HETATM 15031 O O      . HOH H 4 .   ? -27.297 4.174   3.996   1.00 50.26  ? 822 HOH B O      1 
HETATM 15032 O O      . HOH H 4 .   ? -0.117  16.479  -13.781 1.00 22.38  ? 823 HOH B O      1 
HETATM 15033 O O      . HOH H 4 .   ? -27.988 24.472  -37.820 1.00 33.83  ? 824 HOH B O      1 
HETATM 15034 O O      . HOH H 4 .   ? -11.022 45.170  -26.292 1.00 45.80  ? 825 HOH B O      1 
HETATM 15035 O O      . HOH H 4 .   ? -29.902 25.797  -39.447 1.00 29.52  ? 826 HOH B O      1 
HETATM 15036 O O      . HOH H 4 .   ? -24.075 33.237  -47.512 1.00 27.50  ? 827 HOH B O      1 
HETATM 15037 O O      . HOH H 4 .   ? 8.199   27.118  -12.713 1.00 28.45  ? 828 HOH B O      1 
HETATM 15038 O O      . HOH H 4 .   ? -4.092  9.602   -9.021  1.00 25.92  ? 829 HOH B O      1 
HETATM 15039 O O      . HOH H 4 .   ? -2.109  25.319  0.169   1.00 40.55  ? 830 HOH B O      1 
HETATM 15040 O O      . HOH H 4 .   ? -7.644  7.521   -7.564  1.00 29.04  ? 831 HOH B O      1 
HETATM 15041 O O      . HOH H 4 .   ? -11.809 42.248  -46.834 1.00 35.74  ? 832 HOH B O      1 
HETATM 15042 O O      . HOH H 4 .   ? -14.412 18.094  -47.002 1.00 41.73  ? 833 HOH B O      1 
HETATM 15043 O O      . HOH H 4 .   ? -0.616  34.742  -13.639 1.00 30.83  ? 834 HOH B O      1 
HETATM 15044 O O      . HOH H 4 .   ? -34.140 8.982   0.186   1.00 43.56  ? 835 HOH B O      1 
HETATM 15045 O O      . HOH H 4 .   ? -23.143 19.481  3.791   1.00 44.03  ? 836 HOH B O      1 
HETATM 15046 O O      . HOH H 4 .   ? -31.317 26.542  -35.450 1.00 46.22  ? 837 HOH B O      1 
HETATM 15047 O O      . HOH H 4 .   ? -26.750 19.524  -13.965 1.00 38.78  ? 838 HOH B O      1 
HETATM 15048 O O      . HOH H 4 .   ? -9.379  36.283  -13.445 1.00 36.56  ? 839 HOH B O      1 
HETATM 15049 O O      . HOH H 4 .   ? -36.524 5.434   -12.729 1.00 41.93  ? 840 HOH B O      1 
HETATM 15050 O O      . HOH H 4 .   ? 6.860   33.635  -15.229 1.00 41.43  ? 841 HOH B O      1 
HETATM 15051 O O      . HOH H 4 .   ? -22.751 16.860  -0.646  1.00 31.72  ? 842 HOH B O      1 
HETATM 15052 O O      . HOH H 4 .   ? -13.064 37.721  -2.433  1.00 35.04  ? 843 HOH B O      1 
HETATM 15053 O O      . HOH H 4 .   ? -14.176 6.866   0.038   1.00 40.16  ? 844 HOH B O      1 
HETATM 15054 O O      . HOH H 4 .   ? -18.221 19.069  -24.867 1.00 33.79  ? 845 HOH B O      1 
HETATM 15055 O O      . HOH H 4 .   ? -24.788 22.582  2.964   1.00 39.79  ? 846 HOH B O      1 
HETATM 15056 O O      . HOH H 4 .   ? -19.267 14.226  2.830   1.00 41.42  ? 847 HOH B O      1 
HETATM 15057 O O      . HOH H 4 .   ? -10.787 46.683  -40.749 1.00 34.49  ? 848 HOH B O      1 
HETATM 15058 O O      . HOH H 4 .   ? -12.215 30.585  -54.834 1.00 35.31  ? 849 HOH B O      1 
HETATM 15059 O O      . HOH H 4 .   ? -20.524 37.193  -22.205 1.00 45.29  ? 850 HOH B O      1 
HETATM 15060 O O      . HOH H 4 .   ? -23.815 27.216  -17.303 1.00 35.68  ? 851 HOH B O      1 
HETATM 15061 O O      . HOH H 4 .   ? -3.674  14.238  -35.177 1.00 40.44  ? 852 HOH B O      1 
HETATM 15062 O O      . HOH H 4 .   ? -17.530 5.063   -23.679 1.00 23.91  ? 853 HOH B O      1 
HETATM 15063 O O      . HOH H 4 .   ? -27.818 24.423  -18.638 1.00 39.18  ? 854 HOH B O      1 
HETATM 15064 O O      . HOH H 4 .   ? -28.505 25.989  -27.708 1.00 42.40  ? 855 HOH B O      1 
HETATM 15065 O O      . HOH H 4 .   ? -21.101 18.896  -49.093 1.00 44.73  ? 856 HOH B O      1 
HETATM 15066 O O      . HOH H 4 .   ? -0.271  18.926  -38.834 1.00 38.43  ? 857 HOH B O      1 
HETATM 15067 O O      . HOH H 4 .   ? -36.412 9.355   -19.685 1.00 46.84  ? 858 HOH B O      1 
HETATM 15068 O O      . HOH H 4 .   ? -26.592 33.206  -46.420 1.00 42.24  ? 859 HOH B O      1 
HETATM 15069 O O      . HOH H 4 .   ? -7.365  17.337  -30.539 1.00 22.55  ? 860 HOH B O      1 
HETATM 15070 O O      . HOH H 4 .   ? -13.773 -9.027  -17.895 1.00 26.53  ? 861 HOH B O      1 
HETATM 15071 O O      . HOH H 4 .   ? -6.756  36.386  -2.657  1.00 33.75  ? 862 HOH B O      1 
HETATM 15072 O O      . HOH H 4 .   ? 4.409   27.365  -42.770 1.00 42.71  ? 863 HOH B O      1 
HETATM 15073 O O      . HOH H 4 .   ? -3.756  22.722  -55.718 1.00 41.47  ? 864 HOH B O      1 
HETATM 15074 O O      . HOH H 4 .   ? -11.119 15.699  0.156   1.00 32.31  ? 865 HOH B O      1 
HETATM 15075 O O      . HOH H 4 .   ? -22.362 28.699  -30.424 1.00 35.29  ? 866 HOH B O      1 
HETATM 15076 O O      . HOH H 4 .   ? 3.834   28.226  -40.404 1.00 41.08  ? 867 HOH B O      1 
HETATM 15077 O O      . HOH H 4 .   ? -13.736 14.675  4.235   1.00 40.50  ? 868 HOH B O      1 
HETATM 15078 O O      . HOH H 4 .   ? 1.292   14.337  -13.869 1.00 31.37  ? 869 HOH B O      1 
HETATM 15079 O O      . HOH H 4 .   ? 5.282   31.868  -34.578 1.00 30.23  ? 870 HOH B O      1 
HETATM 15080 O O      . HOH H 4 .   ? 2.719   33.916  -37.409 1.00 29.32  ? 871 HOH B O      1 
HETATM 15081 O O      . HOH H 4 .   ? -25.963 27.187  -49.960 1.00 35.94  ? 872 HOH B O      1 
HETATM 15082 O O      . HOH H 4 .   ? 3.130   30.022  -37.750 1.00 35.62  ? 873 HOH B O      1 
HETATM 15083 O O      . HOH H 4 .   ? 2.263   43.250  -27.843 1.00 44.71  ? 874 HOH B O      1 
HETATM 15084 O O      . HOH H 4 .   ? -0.036  13.711  -10.353 1.00 31.30  ? 875 HOH B O      1 
HETATM 15085 O O      . HOH H 4 .   ? -1.432  28.623  6.809   1.00 32.10  ? 876 HOH B O      1 
HETATM 15086 O O      . HOH H 4 .   ? -4.758  12.155  -26.622 1.00 23.41  ? 877 HOH B O      1 
HETATM 15087 O O      . HOH H 4 .   ? 6.906   31.814  -21.664 1.00 42.49  ? 878 HOH B O      1 
HETATM 15088 O O      . HOH H 4 .   ? -11.780 35.327  -13.003 1.00 33.91  ? 879 HOH B O      1 
HETATM 15089 O O      . HOH H 4 .   ? -1.919  23.756  -1.541  1.00 40.84  ? 880 HOH B O      1 
HETATM 15090 O O      . HOH H 4 .   ? -8.007  4.741   -7.701  1.00 38.52  ? 881 HOH B O      1 
HETATM 15091 O O      . HOH H 4 .   ? -27.307 22.775  -34.491 1.00 43.44  ? 882 HOH B O      1 
HETATM 15092 O O      . HOH H 4 .   ? -26.983 31.347  -48.402 1.00 42.40  ? 883 HOH B O      1 
HETATM 15093 O O      . HOH H 4 .   ? -5.500  37.861  -44.062 1.00 37.09  ? 884 HOH B O      1 
HETATM 15094 O O      . HOH H 4 .   ? -14.185 0.118   -2.524  1.00 35.98  ? 885 HOH B O      1 
HETATM 15095 O O      . HOH H 4 .   ? -5.015  7.223   -7.924  1.00 33.43  ? 886 HOH B O      1 
HETATM 15096 O O      . HOH H 4 .   ? -2.699  11.410  -7.571  1.00 34.35  ? 887 HOH B O      1 
HETATM 15097 O O      . HOH H 4 .   ? -12.530 49.188  -40.619 1.00 41.18  ? 888 HOH B O      1 
HETATM 15098 O O      . HOH H 4 .   ? -2.663  44.275  -21.378 1.00 36.17  ? 889 HOH B O      1 
HETATM 15099 O O      . HOH H 4 .   ? -22.598 16.906  2.034   1.00 37.27  ? 890 HOH B O      1 
HETATM 15100 O O      . HOH H 4 .   ? -41.628 28.481  -0.024  1.00 41.90  ? 891 HOH B O      1 
HETATM 15101 O O      . HOH H 4 .   ? 1.346   44.317  -30.859 1.00 46.13  ? 892 HOH B O      1 
HETATM 15102 O O      . HOH H 4 .   ? 10.168  28.489  -13.947 1.00 40.77  ? 893 HOH B O      1 
HETATM 15103 O O      . HOH H 4 .   ? -0.892  16.151  -5.583  1.00 40.78  ? 894 HOH B O      1 
HETATM 15104 O O      . HOH H 4 .   ? -7.266  24.525  5.165   1.00 22.82  ? 895 HOH B O      1 
HETATM 15105 O O      . HOH H 4 .   ? -17.259 18.218  -47.043 1.00 35.06  ? 896 HOH B O      1 
HETATM 15106 O O      . HOH H 4 .   ? -23.237 -3.805  -6.852  1.00 34.88  ? 897 HOH B O      1 
HETATM 15107 O O      . HOH H 4 .   ? -19.779 17.063  2.215   1.00 31.40  ? 898 HOH B O      1 
HETATM 15108 O O      . HOH H 4 .   ? -15.381 15.087  -42.915 1.00 38.57  ? 899 HOH B O      1 
HETATM 15109 O O      . HOH H 4 .   ? -6.049  29.240  6.073   1.00 25.14  ? 900 HOH B O      1 
HETATM 15110 O O      . HOH H 4 .   ? -16.944 38.647  -5.647  1.00 42.39  ? 901 HOH B O      1 
HETATM 15111 O O      . HOH H 4 .   ? 2.910   40.420  -24.245 1.00 39.50  ? 902 HOH B O      1 
HETATM 15112 O O      . HOH H 4 .   ? -14.594 38.218  -4.241  1.00 46.07  ? 903 HOH B O      1 
HETATM 15113 O O      . HOH H 4 .   ? -27.427 22.257  -51.387 1.00 43.03  ? 904 HOH B O      1 
HETATM 15114 O O      . HOH H 4 .   ? -17.467 15.352  -40.850 1.00 37.06  ? 905 HOH B O      1 
HETATM 15115 O O      . HOH H 4 .   ? -6.308  31.759  -49.091 1.00 42.67  ? 906 HOH B O      1 
HETATM 15116 O O      . HOH H 4 .   ? 5.065   25.895  -37.690 1.00 39.07  ? 907 HOH B O      1 
# 
