data_9J0I
# 
_entry.id   9J0I 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9J0I         pdb_00009j0i 10.2210/pdb9j0i/pdb 
WWPDB D_1300050080 ?            ?                   
EMDB  EMD-61055    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-04 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9J0I 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'UDP-Glucuronic acid bound purinergic receptor P2Y14 complex with Gi' 
_pdbx_database_related.db_id          EMD-61055 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 jwang@ibp.ac.cn        Jiangyun Wang ? 'principal investigator/group leader' 0000-0002-5974-1562 
5 lifahui@moon.ibp.ac.cn Fahui    Li   ? 'principal investigator/group leader' 0000-0002-5977-2449 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wang, T.X.' 1 0009-0003-7971-8110 
'Gu, Q.C.'   2 0009-0006-3974-0411 
'Tang, W.Q.' 3 0000-0003-2769-7613 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Discov' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2056-5968 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                48 
_citation.page_last                 48 
_citation.title                     
'Structural insights into ligand recognition and activation of human purinergic receptor P2Y14.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41421-025-00799-9 
_citation.pdbx_database_id_PubMed   40360473 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gu, Q.'    1 ?                   
primary 'Lv, Z.'    2 ?                   
primary 'Wang, T.'  3 0009-0003-7971-8110 
primary 'Tang, W.'  4 ?                   
primary 'Guo, X.'   5 ?                   
primary 'Huang, X.' 6 ?                   
primary 'Li, F.'    7 ?                   
primary 'Wang, J.'  8 0000-0002-5974-1562 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'           40415.031 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  41055.867 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ? ? ? 
4 polymer     man 'Soluble cytochrome b562,P2Y purinoceptor 14'                       57407.742 1 ? ? ? ? 
5 polymer     man ScFv16                                                              31870.629 1 ? ? ? ? 
6 non-polymer syn 
;URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
;
580.285   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein'                                                                
2 'Transducin beta chain 1'                                                                                     
3 'G gamma-I'                                                                                                   
4 'Cytochrome b-562,P2Y14 purinergic receptor&#65292;P2Y14,G-protein coupled receptor 105,UDP-glucose receptor' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
2 'polypeptide(L)' no no 
;MHHHHHHGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRL
LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC
RFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI
NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA
GHDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
;MHHHHHHGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRL
LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC
RFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI
NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA
GHDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
4 'polypeptide(L)' no no 
;MKTIIALSYIFCLVFADYKDDDDAGRAHHHHHHHHHHENLYFQSGAPADLEDNWETLNDNLKVIEKADNAAQVKDALTKM
RAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLEFLEVLF
QGPAINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFK
ILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNI
ILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS
IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQ
NDLDISRIKRGNTTLESTDTL
;
;MKTIIALSYIFCLVFADYKDDDDAGRAHHHHHHHHHHENLYFQSGAPADLEDNWETLNDNLKVIEKADNAAQVKDALTKM
RAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLEFLEVLF
QGPAINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFK
ILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNI
ILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS
IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQ
NDLDISRIKRGNTTLESTDTL
;
R ? 
5 'polypeptide(L)' no no 
;MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFADVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPE
KGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLFLQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSG
GGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDR
FSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLELKAAAHHHHHHHH
;
;MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFADVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPE
KGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLFLQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSG
GGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDR
FSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLELKAAAHHHHHHHH
;
S ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        
;URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
;
_pdbx_entity_nonpoly.comp_id     UGA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   THR n 
1 5   LEU n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  ASP n 
1 21  ARG n 
1 22  ASN n 
1 23  LEU n 
1 24  ARG n 
1 25  GLU n 
1 26  ASP n 
1 27  GLY n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ALA n 
1 32  ARG n 
1 33  GLU n 
1 34  VAL n 
1 35  LYS n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  GLY n 
1 43  GLU n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  SER n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  LYS n 
1 55  ILE n 
1 56  ILE n 
1 57  HIS n 
1 58  GLU n 
1 59  ALA n 
1 60  GLY n 
1 61  TYR n 
1 62  SER n 
1 63  GLU n 
1 64  GLU n 
1 65  GLU n 
1 66  CYS n 
1 67  LYS n 
1 68  GLN n 
1 69  TYR n 
1 70  LYS n 
1 71  ALA n 
1 72  VAL n 
1 73  VAL n 
1 74  TYR n 
1 75  SER n 
1 76  ASN n 
1 77  THR n 
1 78  ILE n 
1 79  GLN n 
1 80  SER n 
1 81  ILE n 
1 82  ILE n 
1 83  ALA n 
1 84  ILE n 
1 85  ILE n 
1 86  ARG n 
1 87  ALA n 
1 88  MET n 
1 89  GLY n 
1 90  ARG n 
1 91  LEU n 
1 92  LYS n 
1 93  ILE n 
1 94  ASP n 
1 95  PHE n 
1 96  GLY n 
1 97  ASP n 
1 98  SER n 
1 99  ALA n 
1 100 ARG n 
1 101 ALA n 
1 102 ASP n 
1 103 ASP n 
1 104 ALA n 
1 105 ARG n 
1 106 GLN n 
1 107 LEU n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 ALA n 
1 112 GLY n 
1 113 ALA n 
1 114 ALA n 
1 115 GLU n 
1 116 GLU n 
1 117 GLY n 
1 118 PHE n 
1 119 MET n 
1 120 THR n 
1 121 ALA n 
1 122 GLU n 
1 123 LEU n 
1 124 ALA n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 LYS n 
1 129 ARG n 
1 130 LEU n 
1 131 TRP n 
1 132 LYS n 
1 133 ASP n 
1 134 SER n 
1 135 GLY n 
1 136 VAL n 
1 137 GLN n 
1 138 ALA n 
1 139 CYS n 
1 140 PHE n 
1 141 ASN n 
1 142 ARG n 
1 143 SER n 
1 144 ARG n 
1 145 GLU n 
1 146 TYR n 
1 147 GLN n 
1 148 LEU n 
1 149 ASN n 
1 150 ASP n 
1 151 SER n 
1 152 ALA n 
1 153 ALA n 
1 154 TYR n 
1 155 TYR n 
1 156 LEU n 
1 157 ASN n 
1 158 ASP n 
1 159 LEU n 
1 160 ASP n 
1 161 ARG n 
1 162 ILE n 
1 163 ALA n 
1 164 GLN n 
1 165 PRO n 
1 166 ASN n 
1 167 TYR n 
1 168 ILE n 
1 169 PRO n 
1 170 THR n 
1 171 GLN n 
1 172 GLN n 
1 173 ASP n 
1 174 VAL n 
1 175 LEU n 
1 176 ARG n 
1 177 THR n 
1 178 ARG n 
1 179 VAL n 
1 180 LYS n 
1 181 THR n 
1 182 THR n 
1 183 GLY n 
1 184 ILE n 
1 185 VAL n 
1 186 GLU n 
1 187 THR n 
1 188 HIS n 
1 189 PHE n 
1 190 THR n 
1 191 PHE n 
1 192 LYS n 
1 193 ASP n 
1 194 LEU n 
1 195 HIS n 
1 196 PHE n 
1 197 LYS n 
1 198 MET n 
1 199 PHE n 
1 200 ASP n 
1 201 VAL n 
1 202 GLY n 
1 203 GLY n 
1 204 GLN n 
1 205 ARG n 
1 206 SER n 
1 207 GLU n 
1 208 ARG n 
1 209 LYS n 
1 210 LYS n 
1 211 TRP n 
1 212 ILE n 
1 213 HIS n 
1 214 CYS n 
1 215 PHE n 
1 216 GLU n 
1 217 GLY n 
1 218 VAL n 
1 219 THR n 
1 220 ALA n 
1 221 ILE n 
1 222 ILE n 
1 223 PHE n 
1 224 CYS n 
1 225 VAL n 
1 226 ALA n 
1 227 LEU n 
1 228 SER n 
1 229 ASP n 
1 230 TYR n 
1 231 ASP n 
1 232 LEU n 
1 233 VAL n 
1 234 LEU n 
1 235 ALA n 
1 236 GLU n 
1 237 ASP n 
1 238 GLU n 
1 239 GLU n 
1 240 MET n 
1 241 ASN n 
1 242 ARG n 
1 243 MET n 
1 244 HIS n 
1 245 GLU n 
1 246 SER n 
1 247 MET n 
1 248 LYS n 
1 249 LEU n 
1 250 PHE n 
1 251 ASP n 
1 252 SER n 
1 253 ILE n 
1 254 CYS n 
1 255 ASN n 
1 256 ASN n 
1 257 LYS n 
1 258 TRP n 
1 259 PHE n 
1 260 THR n 
1 261 ASP n 
1 262 THR n 
1 263 SER n 
1 264 ILE n 
1 265 ILE n 
1 266 LEU n 
1 267 PHE n 
1 268 LEU n 
1 269 ASN n 
1 270 LYS n 
1 271 LYS n 
1 272 ASP n 
1 273 LEU n 
1 274 PHE n 
1 275 GLU n 
1 276 GLU n 
1 277 LYS n 
1 278 ILE n 
1 279 LYS n 
1 280 LYS n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 THR n 
1 285 ILE n 
1 286 CYS n 
1 287 TYR n 
1 288 PRO n 
1 289 GLU n 
1 290 TYR n 
1 291 ALA n 
1 292 GLY n 
1 293 SER n 
1 294 ASN n 
1 295 THR n 
1 296 TYR n 
1 297 GLU n 
1 298 GLU n 
1 299 ALA n 
1 300 ALA n 
1 301 ALA n 
1 302 TYR n 
1 303 ILE n 
1 304 GLN n 
1 305 CYS n 
1 306 GLN n 
1 307 PHE n 
1 308 GLU n 
1 309 ASP n 
1 310 LEU n 
1 311 ASN n 
1 312 LYS n 
1 313 ARG n 
1 314 LYS n 
1 315 ASP n 
1 316 THR n 
1 317 LYS n 
1 318 GLU n 
1 319 ILE n 
1 320 TYR n 
1 321 THR n 
1 322 HIS n 
1 323 PHE n 
1 324 THR n 
1 325 CYS n 
1 326 ALA n 
1 327 THR n 
1 328 ASP n 
1 329 THR n 
1 330 LYS n 
1 331 ASN n 
1 332 VAL n 
1 333 GLN n 
1 334 PHE n 
1 335 VAL n 
1 336 PHE n 
1 337 ASP n 
1 338 ALA n 
1 339 VAL n 
1 340 THR n 
1 341 ASP n 
1 342 VAL n 
1 343 ILE n 
1 344 ILE n 
1 345 LYS n 
1 346 ASN n 
1 347 ASN n 
1 348 LEU n 
1 349 LYS n 
1 350 ASP n 
1 351 CYS n 
1 352 GLY n 
1 353 LEU n 
1 354 PHE n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   GLY n 
2 9   SER n 
2 10  LEU n 
2 11  LEU n 
2 12  GLN n 
2 13  SER n 
2 14  GLU n 
2 15  LEU n 
2 16  ASP n 
2 17  GLN n 
2 18  LEU n 
2 19  ARG n 
2 20  GLN n 
2 21  GLU n 
2 22  ALA n 
2 23  GLU n 
2 24  GLN n 
2 25  LEU n 
2 26  LYS n 
2 27  ASN n 
2 28  GLN n 
2 29  ILE n 
2 30  ARG n 
2 31  ASP n 
2 32  ALA n 
2 33  ARG n 
2 34  LYS n 
2 35  ALA n 
2 36  CYS n 
2 37  ALA n 
2 38  ASP n 
2 39  ALA n 
2 40  THR n 
2 41  LEU n 
2 42  SER n 
2 43  GLN n 
2 44  ILE n 
2 45  THR n 
2 46  ASN n 
2 47  ASN n 
2 48  ILE n 
2 49  ASP n 
2 50  PRO n 
2 51  VAL n 
2 52  GLY n 
2 53  ARG n 
2 54  ILE n 
2 55  GLN n 
2 56  MET n 
2 57  ARG n 
2 58  THR n 
2 59  ARG n 
2 60  ARG n 
2 61  THR n 
2 62  LEU n 
2 63  ARG n 
2 64  GLY n 
2 65  HIS n 
2 66  LEU n 
2 67  ALA n 
2 68  LYS n 
2 69  ILE n 
2 70  TYR n 
2 71  ALA n 
2 72  MET n 
2 73  HIS n 
2 74  TRP n 
2 75  GLY n 
2 76  THR n 
2 77  ASP n 
2 78  SER n 
2 79  ARG n 
2 80  LEU n 
2 81  LEU n 
2 82  VAL n 
2 83  SER n 
2 84  ALA n 
2 85  SER n 
2 86  GLN n 
2 87  ASP n 
2 88  GLY n 
2 89  LYS n 
2 90  LEU n 
2 91  ILE n 
2 92  ILE n 
2 93  TRP n 
2 94  ASP n 
2 95  SER n 
2 96  TYR n 
2 97  THR n 
2 98  THR n 
2 99  ASN n 
2 100 LYS n 
2 101 VAL n 
2 102 HIS n 
2 103 ALA n 
2 104 ILE n 
2 105 PRO n 
2 106 LEU n 
2 107 ARG n 
2 108 SER n 
2 109 SER n 
2 110 TRP n 
2 111 VAL n 
2 112 MET n 
2 113 THR n 
2 114 CYS n 
2 115 ALA n 
2 116 TYR n 
2 117 ALA n 
2 118 PRO n 
2 119 SER n 
2 120 GLY n 
2 121 ASN n 
2 122 TYR n 
2 123 VAL n 
2 124 ALA n 
2 125 CYS n 
2 126 GLY n 
2 127 GLY n 
2 128 LEU n 
2 129 ASP n 
2 130 ASN n 
2 131 ILE n 
2 132 CYS n 
2 133 SER n 
2 134 ILE n 
2 135 TYR n 
2 136 ASN n 
2 137 LEU n 
2 138 LYS n 
2 139 THR n 
2 140 ARG n 
2 141 GLU n 
2 142 GLY n 
2 143 ASN n 
2 144 VAL n 
2 145 ARG n 
2 146 VAL n 
2 147 SER n 
2 148 ARG n 
2 149 GLU n 
2 150 LEU n 
2 151 ALA n 
2 152 GLY n 
2 153 HIS n 
2 154 THR n 
2 155 GLY n 
2 156 TYR n 
2 157 LEU n 
2 158 SER n 
2 159 CYS n 
2 160 CYS n 
2 161 ARG n 
2 162 PHE n 
2 163 LEU n 
2 164 ASP n 
2 165 ASP n 
2 166 ASN n 
2 167 GLN n 
2 168 ILE n 
2 169 VAL n 
2 170 THR n 
2 171 SER n 
2 172 SER n 
2 173 GLY n 
2 174 ASP n 
2 175 THR n 
2 176 THR n 
2 177 CYS n 
2 178 ALA n 
2 179 LEU n 
2 180 TRP n 
2 181 ASP n 
2 182 ILE n 
2 183 GLU n 
2 184 THR n 
2 185 GLY n 
2 186 GLN n 
2 187 GLN n 
2 188 THR n 
2 189 THR n 
2 190 THR n 
2 191 PHE n 
2 192 THR n 
2 193 GLY n 
2 194 HIS n 
2 195 THR n 
2 196 GLY n 
2 197 ASP n 
2 198 VAL n 
2 199 MET n 
2 200 SER n 
2 201 LEU n 
2 202 SER n 
2 203 LEU n 
2 204 ALA n 
2 205 PRO n 
2 206 ASP n 
2 207 THR n 
2 208 ARG n 
2 209 LEU n 
2 210 PHE n 
2 211 VAL n 
2 212 SER n 
2 213 GLY n 
2 214 ALA n 
2 215 CYS n 
2 216 ASP n 
2 217 ALA n 
2 218 SER n 
2 219 ALA n 
2 220 LYS n 
2 221 LEU n 
2 222 TRP n 
2 223 ASP n 
2 224 VAL n 
2 225 ARG n 
2 226 GLU n 
2 227 GLY n 
2 228 MET n 
2 229 CYS n 
2 230 ARG n 
2 231 GLN n 
2 232 THR n 
2 233 PHE n 
2 234 THR n 
2 235 GLY n 
2 236 HIS n 
2 237 GLU n 
2 238 SER n 
2 239 ASP n 
2 240 ILE n 
2 241 ASN n 
2 242 ALA n 
2 243 ILE n 
2 244 CYS n 
2 245 PHE n 
2 246 PHE n 
2 247 PRO n 
2 248 ASN n 
2 249 GLY n 
2 250 ASN n 
2 251 ALA n 
2 252 PHE n 
2 253 ALA n 
2 254 THR n 
2 255 GLY n 
2 256 SER n 
2 257 ASP n 
2 258 ASP n 
2 259 ALA n 
2 260 THR n 
2 261 CYS n 
2 262 ARG n 
2 263 LEU n 
2 264 PHE n 
2 265 ASP n 
2 266 LEU n 
2 267 ARG n 
2 268 ALA n 
2 269 ASP n 
2 270 GLN n 
2 271 GLU n 
2 272 LEU n 
2 273 MET n 
2 274 THR n 
2 275 TYR n 
2 276 SER n 
2 277 HIS n 
2 278 ASP n 
2 279 ASN n 
2 280 ILE n 
2 281 ILE n 
2 282 CYS n 
2 283 GLY n 
2 284 ILE n 
2 285 THR n 
2 286 SER n 
2 287 VAL n 
2 288 SER n 
2 289 PHE n 
2 290 SER n 
2 291 LYS n 
2 292 SER n 
2 293 GLY n 
2 294 ARG n 
2 295 LEU n 
2 296 LEU n 
2 297 LEU n 
2 298 ALA n 
2 299 GLY n 
2 300 TYR n 
2 301 ASP n 
2 302 ASP n 
2 303 PHE n 
2 304 ASN n 
2 305 CYS n 
2 306 ASN n 
2 307 VAL n 
2 308 TRP n 
2 309 ASP n 
2 310 ALA n 
2 311 LEU n 
2 312 LYS n 
2 313 ALA n 
2 314 ASP n 
2 315 ARG n 
2 316 ALA n 
2 317 GLY n 
2 318 VAL n 
2 319 LEU n 
2 320 ALA n 
2 321 GLY n 
2 322 HIS n 
2 323 ASP n 
2 324 ASN n 
2 325 ARG n 
2 326 VAL n 
2 327 SER n 
2 328 CYS n 
2 329 LEU n 
2 330 GLY n 
2 331 VAL n 
2 332 THR n 
2 333 ASP n 
2 334 ASP n 
2 335 GLY n 
2 336 MET n 
2 337 ALA n 
2 338 VAL n 
2 339 ALA n 
2 340 THR n 
2 341 GLY n 
2 342 SER n 
2 343 TRP n 
2 344 ASP n 
2 345 SER n 
2 346 PHE n 
2 347 LEU n 
2 348 LYS n 
2 349 ILE n 
2 350 TRP n 
2 351 ASN n 
2 352 GLY n 
2 353 SER n 
2 354 SER n 
2 355 GLY n 
2 356 GLY n 
2 357 GLY n 
2 358 GLY n 
2 359 SER n 
2 360 GLY n 
2 361 GLY n 
2 362 GLY n 
2 363 GLY n 
2 364 SER n 
2 365 SER n 
2 366 GLY n 
2 367 VAL n 
2 368 SER n 
2 369 GLY n 
2 370 TRP n 
2 371 ARG n 
2 372 LEU n 
2 373 PHE n 
2 374 LYS n 
2 375 LYS n 
2 376 ILE n 
2 377 SER n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   MET n 
4 2   LYS n 
4 3   THR n 
4 4   ILE n 
4 5   ILE n 
4 6   ALA n 
4 7   LEU n 
4 8   SER n 
4 9   TYR n 
4 10  ILE n 
4 11  PHE n 
4 12  CYS n 
4 13  LEU n 
4 14  VAL n 
4 15  PHE n 
4 16  ALA n 
4 17  ASP n 
4 18  TYR n 
4 19  LYS n 
4 20  ASP n 
4 21  ASP n 
4 22  ASP n 
4 23  ASP n 
4 24  ALA n 
4 25  GLY n 
4 26  ARG n 
4 27  ALA n 
4 28  HIS n 
4 29  HIS n 
4 30  HIS n 
4 31  HIS n 
4 32  HIS n 
4 33  HIS n 
4 34  HIS n 
4 35  HIS n 
4 36  HIS n 
4 37  HIS n 
4 38  GLU n 
4 39  ASN n 
4 40  LEU n 
4 41  TYR n 
4 42  PHE n 
4 43  GLN n 
4 44  SER n 
4 45  GLY n 
4 46  ALA n 
4 47  PRO n 
4 48  ALA n 
4 49  ASP n 
4 50  LEU n 
4 51  GLU n 
4 52  ASP n 
4 53  ASN n 
4 54  TRP n 
4 55  GLU n 
4 56  THR n 
4 57  LEU n 
4 58  ASN n 
4 59  ASP n 
4 60  ASN n 
4 61  LEU n 
4 62  LYS n 
4 63  VAL n 
4 64  ILE n 
4 65  GLU n 
4 66  LYS n 
4 67  ALA n 
4 68  ASP n 
4 69  ASN n 
4 70  ALA n 
4 71  ALA n 
4 72  GLN n 
4 73  VAL n 
4 74  LYS n 
4 75  ASP n 
4 76  ALA n 
4 77  LEU n 
4 78  THR n 
4 79  LYS n 
4 80  MET n 
4 81  ARG n 
4 82  ALA n 
4 83  ALA n 
4 84  ALA n 
4 85  LEU n 
4 86  ASP n 
4 87  ALA n 
4 88  GLN n 
4 89  LYS n 
4 90  ALA n 
4 91  THR n 
4 92  PRO n 
4 93  PRO n 
4 94  LYS n 
4 95  LEU n 
4 96  GLU n 
4 97  ASP n 
4 98  LYS n 
4 99  SER n 
4 100 PRO n 
4 101 ASP n 
4 102 SER n 
4 103 PRO n 
4 104 GLU n 
4 105 MET n 
4 106 LYS n 
4 107 ASP n 
4 108 PHE n 
4 109 ARG n 
4 110 HIS n 
4 111 GLY n 
4 112 PHE n 
4 113 ASP n 
4 114 ILE n 
4 115 LEU n 
4 116 VAL n 
4 117 GLY n 
4 118 GLN n 
4 119 ILE n 
4 120 ASP n 
4 121 ASP n 
4 122 ALA n 
4 123 LEU n 
4 124 LYS n 
4 125 LEU n 
4 126 ALA n 
4 127 ASN n 
4 128 GLU n 
4 129 GLY n 
4 130 LYS n 
4 131 VAL n 
4 132 LYS n 
4 133 GLU n 
4 134 ALA n 
4 135 GLN n 
4 136 ALA n 
4 137 ALA n 
4 138 ALA n 
4 139 GLU n 
4 140 GLN n 
4 141 LEU n 
4 142 LYS n 
4 143 THR n 
4 144 THR n 
4 145 ARG n 
4 146 ASN n 
4 147 ALA n 
4 148 TYR n 
4 149 ILE n 
4 150 GLN n 
4 151 LYS n 
4 152 TYR n 
4 153 LEU n 
4 154 GLU n 
4 155 PHE n 
4 156 LEU n 
4 157 GLU n 
4 158 VAL n 
4 159 LEU n 
4 160 PHE n 
4 161 GLN n 
4 162 GLY n 
4 163 PRO n 
4 164 ALA n 
4 165 ILE n 
4 166 ASN n 
4 167 SER n 
4 168 THR n 
4 169 SER n 
4 170 THR n 
4 171 GLN n 
4 172 PRO n 
4 173 PRO n 
4 174 ASP n 
4 175 GLU n 
4 176 SER n 
4 177 CYS n 
4 178 SER n 
4 179 GLN n 
4 180 ASN n 
4 181 LEU n 
4 182 LEU n 
4 183 ILE n 
4 184 THR n 
4 185 GLN n 
4 186 GLN n 
4 187 ILE n 
4 188 ILE n 
4 189 PRO n 
4 190 VAL n 
4 191 LEU n 
4 192 TYR n 
4 193 CYS n 
4 194 MET n 
4 195 VAL n 
4 196 PHE n 
4 197 ILE n 
4 198 ALA n 
4 199 GLY n 
4 200 ILE n 
4 201 LEU n 
4 202 LEU n 
4 203 ASN n 
4 204 GLY n 
4 205 VAL n 
4 206 SER n 
4 207 GLY n 
4 208 TRP n 
4 209 ILE n 
4 210 PHE n 
4 211 PHE n 
4 212 TYR n 
4 213 VAL n 
4 214 PRO n 
4 215 SER n 
4 216 SER n 
4 217 LYS n 
4 218 SER n 
4 219 PHE n 
4 220 ILE n 
4 221 ILE n 
4 222 TYR n 
4 223 LEU n 
4 224 LYS n 
4 225 ASN n 
4 226 ILE n 
4 227 VAL n 
4 228 ILE n 
4 229 ALA n 
4 230 ASP n 
4 231 PHE n 
4 232 VAL n 
4 233 MET n 
4 234 SER n 
4 235 LEU n 
4 236 THR n 
4 237 PHE n 
4 238 PRO n 
4 239 PHE n 
4 240 LYS n 
4 241 ILE n 
4 242 LEU n 
4 243 GLY n 
4 244 ASP n 
4 245 SER n 
4 246 GLY n 
4 247 LEU n 
4 248 GLY n 
4 249 PRO n 
4 250 TRP n 
4 251 GLN n 
4 252 LEU n 
4 253 ASN n 
4 254 VAL n 
4 255 PHE n 
4 256 VAL n 
4 257 CYS n 
4 258 ARG n 
4 259 VAL n 
4 260 SER n 
4 261 ALA n 
4 262 VAL n 
4 263 LEU n 
4 264 PHE n 
4 265 TYR n 
4 266 VAL n 
4 267 ASN n 
4 268 MET n 
4 269 TYR n 
4 270 VAL n 
4 271 SER n 
4 272 ILE n 
4 273 VAL n 
4 274 PHE n 
4 275 PHE n 
4 276 GLY n 
4 277 LEU n 
4 278 ILE n 
4 279 SER n 
4 280 PHE n 
4 281 ASP n 
4 282 ARG n 
4 283 TYR n 
4 284 TYR n 
4 285 LYS n 
4 286 ILE n 
4 287 VAL n 
4 288 LYS n 
4 289 PRO n 
4 290 LEU n 
4 291 TRP n 
4 292 THR n 
4 293 SER n 
4 294 PHE n 
4 295 ILE n 
4 296 GLN n 
4 297 SER n 
4 298 VAL n 
4 299 SER n 
4 300 TYR n 
4 301 SER n 
4 302 LYS n 
4 303 LEU n 
4 304 LEU n 
4 305 SER n 
4 306 VAL n 
4 307 ILE n 
4 308 VAL n 
4 309 TRP n 
4 310 MET n 
4 311 LEU n 
4 312 MET n 
4 313 LEU n 
4 314 LEU n 
4 315 LEU n 
4 316 ALA n 
4 317 VAL n 
4 318 PRO n 
4 319 ASN n 
4 320 ILE n 
4 321 ILE n 
4 322 LEU n 
4 323 THR n 
4 324 ASN n 
4 325 GLN n 
4 326 SER n 
4 327 VAL n 
4 328 ARG n 
4 329 GLU n 
4 330 VAL n 
4 331 THR n 
4 332 GLN n 
4 333 ILE n 
4 334 LYS n 
4 335 CYS n 
4 336 ILE n 
4 337 GLU n 
4 338 LEU n 
4 339 LYS n 
4 340 SER n 
4 341 GLU n 
4 342 LEU n 
4 343 GLY n 
4 344 ARG n 
4 345 LYS n 
4 346 TRP n 
4 347 HIS n 
4 348 LYS n 
4 349 ALA n 
4 350 SER n 
4 351 ASN n 
4 352 TYR n 
4 353 ILE n 
4 354 PHE n 
4 355 VAL n 
4 356 ALA n 
4 357 ILE n 
4 358 PHE n 
4 359 TRP n 
4 360 ILE n 
4 361 VAL n 
4 362 PHE n 
4 363 LEU n 
4 364 LEU n 
4 365 LEU n 
4 366 ILE n 
4 367 VAL n 
4 368 PHE n 
4 369 TYR n 
4 370 THR n 
4 371 ALA n 
4 372 ILE n 
4 373 THR n 
4 374 LYS n 
4 375 LYS n 
4 376 ILE n 
4 377 PHE n 
4 378 LYS n 
4 379 SER n 
4 380 HIS n 
4 381 LEU n 
4 382 LYS n 
4 383 SER n 
4 384 SER n 
4 385 ARG n 
4 386 ASN n 
4 387 SER n 
4 388 THR n 
4 389 SER n 
4 390 VAL n 
4 391 LYS n 
4 392 LYS n 
4 393 LYS n 
4 394 SER n 
4 395 SER n 
4 396 ARG n 
4 397 ASN n 
4 398 ILE n 
4 399 PHE n 
4 400 SER n 
4 401 ILE n 
4 402 VAL n 
4 403 PHE n 
4 404 VAL n 
4 405 PHE n 
4 406 PHE n 
4 407 VAL n 
4 408 CYS n 
4 409 PHE n 
4 410 VAL n 
4 411 PRO n 
4 412 TYR n 
4 413 HIS n 
4 414 ILE n 
4 415 ALA n 
4 416 ARG n 
4 417 ILE n 
4 418 PRO n 
4 419 TYR n 
4 420 THR n 
4 421 LYS n 
4 422 SER n 
4 423 GLN n 
4 424 THR n 
4 425 GLU n 
4 426 ALA n 
4 427 HIS n 
4 428 TYR n 
4 429 SER n 
4 430 CYS n 
4 431 GLN n 
4 432 SER n 
4 433 LYS n 
4 434 GLU n 
4 435 ILE n 
4 436 LEU n 
4 437 ARG n 
4 438 TYR n 
4 439 MET n 
4 440 LYS n 
4 441 GLU n 
4 442 PHE n 
4 443 THR n 
4 444 LEU n 
4 445 LEU n 
4 446 LEU n 
4 447 SER n 
4 448 ALA n 
4 449 ALA n 
4 450 ASN n 
4 451 VAL n 
4 452 CYS n 
4 453 LEU n 
4 454 ASP n 
4 455 PRO n 
4 456 ILE n 
4 457 ILE n 
4 458 TYR n 
4 459 PHE n 
4 460 PHE n 
4 461 LEU n 
4 462 CYS n 
4 463 GLN n 
4 464 PRO n 
4 465 PHE n 
4 466 ARG n 
4 467 GLU n 
4 468 ILE n 
4 469 LEU n 
4 470 CYS n 
4 471 LYS n 
4 472 LYS n 
4 473 LEU n 
4 474 HIS n 
4 475 ILE n 
4 476 PRO n 
4 477 LEU n 
4 478 LYS n 
4 479 ALA n 
4 480 GLN n 
4 481 ASN n 
4 482 ASP n 
4 483 LEU n 
4 484 ASP n 
4 485 ILE n 
4 486 SER n 
4 487 ARG n 
4 488 ILE n 
4 489 LYS n 
4 490 ARG n 
4 491 GLY n 
4 492 ASN n 
4 493 THR n 
4 494 THR n 
4 495 LEU n 
4 496 GLU n 
4 497 SER n 
4 498 THR n 
4 499 ASP n 
4 500 THR n 
4 501 LEU n 
5 1   MET n 
5 2   LEU n 
5 3   LEU n 
5 4   VAL n 
5 5   ASN n 
5 6   GLN n 
5 7   SER n 
5 8   HIS n 
5 9   GLN n 
5 10  GLY n 
5 11  PHE n 
5 12  ASN n 
5 13  LYS n 
5 14  GLU n 
5 15  HIS n 
5 16  THR n 
5 17  SER n 
5 18  LYS n 
5 19  MET n 
5 20  VAL n 
5 21  SER n 
5 22  ALA n 
5 23  ILE n 
5 24  VAL n 
5 25  LEU n 
5 26  TYR n 
5 27  VAL n 
5 28  LEU n 
5 29  LEU n 
5 30  ALA n 
5 31  ALA n 
5 32  ALA n 
5 33  ALA n 
5 34  HIS n 
5 35  SER n 
5 36  ALA n 
5 37  PHE n 
5 38  ALA n 
5 39  ASP n 
5 40  VAL n 
5 41  GLN n 
5 42  LEU n 
5 43  VAL n 
5 44  GLU n 
5 45  SER n 
5 46  GLY n 
5 47  GLY n 
5 48  GLY n 
5 49  LEU n 
5 50  VAL n 
5 51  GLN n 
5 52  PRO n 
5 53  GLY n 
5 54  GLY n 
5 55  SER n 
5 56  ARG n 
5 57  LYS n 
5 58  LEU n 
5 59  SER n 
5 60  CYS n 
5 61  SER n 
5 62  ALA n 
5 63  SER n 
5 64  GLY n 
5 65  PHE n 
5 66  ALA n 
5 67  PHE n 
5 68  SER n 
5 69  SER n 
5 70  PHE n 
5 71  GLY n 
5 72  MET n 
5 73  HIS n 
5 74  TRP n 
5 75  VAL n 
5 76  ARG n 
5 77  GLN n 
5 78  ALA n 
5 79  PRO n 
5 80  GLU n 
5 81  LYS n 
5 82  GLY n 
5 83  LEU n 
5 84  GLU n 
5 85  TRP n 
5 86  VAL n 
5 87  ALA n 
5 88  TYR n 
5 89  ILE n 
5 90  SER n 
5 91  SER n 
5 92  GLY n 
5 93  SER n 
5 94  GLY n 
5 95  THR n 
5 96  ILE n 
5 97  TYR n 
5 98  TYR n 
5 99  ALA n 
5 100 ASP n 
5 101 THR n 
5 102 VAL n 
5 103 LYS n 
5 104 GLY n 
5 105 ARG n 
5 106 PHE n 
5 107 THR n 
5 108 ILE n 
5 109 SER n 
5 110 ARG n 
5 111 ASP n 
5 112 ASP n 
5 113 PRO n 
5 114 LYS n 
5 115 ASN n 
5 116 THR n 
5 117 LEU n 
5 118 PHE n 
5 119 LEU n 
5 120 GLN n 
5 121 MET n 
5 122 THR n 
5 123 SER n 
5 124 LEU n 
5 125 ARG n 
5 126 SER n 
5 127 GLU n 
5 128 ASP n 
5 129 THR n 
5 130 ALA n 
5 131 MET n 
5 132 TYR n 
5 133 TYR n 
5 134 CYS n 
5 135 VAL n 
5 136 ARG n 
5 137 SER n 
5 138 ILE n 
5 139 TYR n 
5 140 TYR n 
5 141 TYR n 
5 142 GLY n 
5 143 SER n 
5 144 SER n 
5 145 PRO n 
5 146 PHE n 
5 147 ASP n 
5 148 PHE n 
5 149 TRP n 
5 150 GLY n 
5 151 GLN n 
5 152 GLY n 
5 153 THR n 
5 154 THR n 
5 155 LEU n 
5 156 THR n 
5 157 VAL n 
5 158 SER n 
5 159 SER n 
5 160 GLY n 
5 161 GLY n 
5 162 GLY n 
5 163 GLY n 
5 164 SER n 
5 165 GLY n 
5 166 GLY n 
5 167 GLY n 
5 168 GLY n 
5 169 SER n 
5 170 GLY n 
5 171 GLY n 
5 172 GLY n 
5 173 GLY n 
5 174 SER n 
5 175 ASP n 
5 176 ILE n 
5 177 VAL n 
5 178 MET n 
5 179 THR n 
5 180 GLN n 
5 181 ALA n 
5 182 THR n 
5 183 SER n 
5 184 SER n 
5 185 VAL n 
5 186 PRO n 
5 187 VAL n 
5 188 THR n 
5 189 PRO n 
5 190 GLY n 
5 191 GLU n 
5 192 SER n 
5 193 VAL n 
5 194 SER n 
5 195 ILE n 
5 196 SER n 
5 197 CYS n 
5 198 ARG n 
5 199 SER n 
5 200 SER n 
5 201 LYS n 
5 202 SER n 
5 203 LEU n 
5 204 LEU n 
5 205 HIS n 
5 206 SER n 
5 207 ASN n 
5 208 GLY n 
5 209 ASN n 
5 210 THR n 
5 211 TYR n 
5 212 LEU n 
5 213 TYR n 
5 214 TRP n 
5 215 PHE n 
5 216 LEU n 
5 217 GLN n 
5 218 ARG n 
5 219 PRO n 
5 220 GLY n 
5 221 GLN n 
5 222 SER n 
5 223 PRO n 
5 224 GLN n 
5 225 LEU n 
5 226 LEU n 
5 227 ILE n 
5 228 TYR n 
5 229 ARG n 
5 230 MET n 
5 231 SER n 
5 232 ASN n 
5 233 LEU n 
5 234 ALA n 
5 235 SER n 
5 236 GLY n 
5 237 VAL n 
5 238 PRO n 
5 239 ASP n 
5 240 ARG n 
5 241 PHE n 
5 242 SER n 
5 243 GLY n 
5 244 SER n 
5 245 GLY n 
5 246 SER n 
5 247 GLY n 
5 248 THR n 
5 249 ALA n 
5 250 PHE n 
5 251 THR n 
5 252 LEU n 
5 253 THR n 
5 254 ILE n 
5 255 SER n 
5 256 ARG n 
5 257 LEU n 
5 258 GLU n 
5 259 ALA n 
5 260 GLU n 
5 261 ASP n 
5 262 VAL n 
5 263 GLY n 
5 264 VAL n 
5 265 TYR n 
5 266 TYR n 
5 267 CYS n 
5 268 MET n 
5 269 GLN n 
5 270 HIS n 
5 271 LEU n 
5 272 GLU n 
5 273 TYR n 
5 274 PRO n 
5 275 LEU n 
5 276 THR n 
5 277 PHE n 
5 278 GLY n 
5 279 ALA n 
5 280 GLY n 
5 281 THR n 
5 282 LYS n 
5 283 LEU n 
5 284 GLU n 
5 285 LEU n 
5 286 LYS n 
5 287 ALA n 
5 288 ALA n 
5 289 ALA n 
5 290 HIS n 
5 291 HIS n 
5 292 HIS n 
5 293 HIS n 
5 294 HIS n 
5 295 HIS n 
5 296 HIS n 
5 297 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   354 human ? GNAI1                      ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   377 human ? GNB1                       ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2                       ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   164 ?     ? cybC                       ? ? ? ? ? ? 'Escherichia coli' 562  ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 2 sample 'Biological sequence' 165 501 human ? 'P2RY14, GPR105, KIAA0001' ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   297 human ? ?                          ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                  ?                     'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                                 ?                     'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                               ?                     'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                          ?                     'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                                 ?                     'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                                ?                     'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                          ?                     'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                  ?                     'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                                ?                     'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                               ?                     'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                  ?                     'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                   ?                     'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                               ?                     'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                            ?                     'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                  ?                     'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                                   ?                     'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                                ?                     'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                               ?                     'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                                 ?                     'C9 H11 N O3'       181.189 
UGA non-polymer         . 
;URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
;
'UDP-GLUCURONIC ACID' 'C15 H22 N2 O18 P2' 580.285 
VAL 'L-peptide linking' y VALINE                                   ?                     'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1    ?   ?   ?   A . n 
A 1 2   GLY 2   2    ?   ?   ?   A . n 
A 1 3   CYS 3   3    3   CYS CYS A . n 
A 1 4   THR 4   4    4   THR THR A . n 
A 1 5   LEU 5   5    5   LEU LEU A . n 
A 1 6   SER 6   6    6   SER SER A . n 
A 1 7   ALA 7   7    7   ALA ALA A . n 
A 1 8   GLU 8   8    8   GLU GLU A . n 
A 1 9   ASP 9   9    9   ASP ASP A . n 
A 1 10  LYS 10  10   10  LYS LYS A . n 
A 1 11  ALA 11  11   11  ALA ALA A . n 
A 1 12  ALA 12  12   12  ALA ALA A . n 
A 1 13  VAL 13  13   13  VAL VAL A . n 
A 1 14  GLU 14  14   14  GLU GLU A . n 
A 1 15  ARG 15  15   15  ARG ARG A . n 
A 1 16  SER 16  16   16  SER SER A . n 
A 1 17  LYS 17  17   17  LYS LYS A . n 
A 1 18  MET 18  18   18  MET MET A . n 
A 1 19  ILE 19  19   19  ILE ILE A . n 
A 1 20  ASP 20  20   20  ASP ASP A . n 
A 1 21  ARG 21  21   21  ARG ARG A . n 
A 1 22  ASN 22  22   22  ASN ASN A . n 
A 1 23  LEU 23  23   23  LEU LEU A . n 
A 1 24  ARG 24  24   24  ARG ARG A . n 
A 1 25  GLU 25  25   25  GLU GLU A . n 
A 1 26  ASP 26  26   26  ASP ASP A . n 
A 1 27  GLY 27  27   27  GLY GLY A . n 
A 1 28  GLU 28  28   28  GLU GLU A . n 
A 1 29  LYS 29  29   29  LYS LYS A . n 
A 1 30  ALA 30  30   30  ALA ALA A . n 
A 1 31  ALA 31  31   31  ALA ALA A . n 
A 1 32  ARG 32  32   32  ARG ARG A . n 
A 1 33  GLU 33  33   33  GLU GLU A . n 
A 1 34  VAL 34  34   34  VAL VAL A . n 
A 1 35  LYS 35  35   35  LYS LYS A . n 
A 1 36  LEU 36  36   36  LEU LEU A . n 
A 1 37  LEU 37  37   37  LEU LEU A . n 
A 1 38  LEU 38  38   38  LEU LEU A . n 
A 1 39  LEU 39  39   39  LEU LEU A . n 
A 1 40  GLY 40  40   40  GLY GLY A . n 
A 1 41  ALA 41  41   41  ALA ALA A . n 
A 1 42  GLY 42  42   42  GLY GLY A . n 
A 1 43  GLU 43  43   43  GLU GLU A . n 
A 1 44  SER 44  44   44  SER SER A . n 
A 1 45  GLY 45  45   45  GLY GLY A . n 
A 1 46  LYS 46  46   46  LYS LYS A . n 
A 1 47  SER 47  47   47  SER SER A . n 
A 1 48  THR 48  48   48  THR THR A . n 
A 1 49  ILE 49  49   49  ILE ILE A . n 
A 1 50  VAL 50  50   50  VAL VAL A . n 
A 1 51  LYS 51  51   51  LYS LYS A . n 
A 1 52  GLN 52  52   52  GLN GLN A . n 
A 1 53  MET 53  53   53  MET MET A . n 
A 1 54  LYS 54  54   ?   ?   ?   A . n 
A 1 55  ILE 55  55   ?   ?   ?   A . n 
A 1 56  ILE 56  56   ?   ?   ?   A . n 
A 1 57  HIS 57  57   ?   ?   ?   A . n 
A 1 58  GLU 58  58   ?   ?   ?   A . n 
A 1 59  ALA 59  59   ?   ?   ?   A . n 
A 1 60  GLY 60  60   ?   ?   ?   A . n 
A 1 61  TYR 61  61   ?   ?   ?   A . n 
A 1 62  SER 62  62   ?   ?   ?   A . n 
A 1 63  GLU 63  63   ?   ?   ?   A . n 
A 1 64  GLU 64  64   ?   ?   ?   A . n 
A 1 65  GLU 65  65   ?   ?   ?   A . n 
A 1 66  CYS 66  66   ?   ?   ?   A . n 
A 1 67  LYS 67  67   ?   ?   ?   A . n 
A 1 68  GLN 68  68   ?   ?   ?   A . n 
A 1 69  TYR 69  69   ?   ?   ?   A . n 
A 1 70  LYS 70  70   ?   ?   ?   A . n 
A 1 71  ALA 71  71   ?   ?   ?   A . n 
A 1 72  VAL 72  72   ?   ?   ?   A . n 
A 1 73  VAL 73  73   ?   ?   ?   A . n 
A 1 74  TYR 74  74   ?   ?   ?   A . n 
A 1 75  SER 75  75   ?   ?   ?   A . n 
A 1 76  ASN 76  76   ?   ?   ?   A . n 
A 1 77  THR 77  77   ?   ?   ?   A . n 
A 1 78  ILE 78  78   ?   ?   ?   A . n 
A 1 79  GLN 79  79   ?   ?   ?   A . n 
A 1 80  SER 80  80   ?   ?   ?   A . n 
A 1 81  ILE 81  81   ?   ?   ?   A . n 
A 1 82  ILE 82  82   ?   ?   ?   A . n 
A 1 83  ALA 83  83   ?   ?   ?   A . n 
A 1 84  ILE 84  84   ?   ?   ?   A . n 
A 1 85  ILE 85  85   ?   ?   ?   A . n 
A 1 86  ARG 86  86   ?   ?   ?   A . n 
A 1 87  ALA 87  87   ?   ?   ?   A . n 
A 1 88  MET 88  88   ?   ?   ?   A . n 
A 1 89  GLY 89  89   ?   ?   ?   A . n 
A 1 90  ARG 90  90   ?   ?   ?   A . n 
A 1 91  LEU 91  91   ?   ?   ?   A . n 
A 1 92  LYS 92  92   ?   ?   ?   A . n 
A 1 93  ILE 93  93   ?   ?   ?   A . n 
A 1 94  ASP 94  94   ?   ?   ?   A . n 
A 1 95  PHE 95  95   ?   ?   ?   A . n 
A 1 96  GLY 96  96   ?   ?   ?   A . n 
A 1 97  ASP 97  97   ?   ?   ?   A . n 
A 1 98  SER 98  98   ?   ?   ?   A . n 
A 1 99  ALA 99  99   ?   ?   ?   A . n 
A 1 100 ARG 100 100  ?   ?   ?   A . n 
A 1 101 ALA 101 101  ?   ?   ?   A . n 
A 1 102 ASP 102 102  ?   ?   ?   A . n 
A 1 103 ASP 103 103  ?   ?   ?   A . n 
A 1 104 ALA 104 104  ?   ?   ?   A . n 
A 1 105 ARG 105 105  ?   ?   ?   A . n 
A 1 106 GLN 106 106  ?   ?   ?   A . n 
A 1 107 LEU 107 107  ?   ?   ?   A . n 
A 1 108 PHE 108 108  ?   ?   ?   A . n 
A 1 109 VAL 109 109  ?   ?   ?   A . n 
A 1 110 LEU 110 110  ?   ?   ?   A . n 
A 1 111 ALA 111 111  ?   ?   ?   A . n 
A 1 112 GLY 112 112  ?   ?   ?   A . n 
A 1 113 ALA 113 113  ?   ?   ?   A . n 
A 1 114 ALA 114 114  ?   ?   ?   A . n 
A 1 115 GLU 115 115  ?   ?   ?   A . n 
A 1 116 GLU 116 116  ?   ?   ?   A . n 
A 1 117 GLY 117 117  ?   ?   ?   A . n 
A 1 118 PHE 118 118  ?   ?   ?   A . n 
A 1 119 MET 119 119  ?   ?   ?   A . n 
A 1 120 THR 120 120  ?   ?   ?   A . n 
A 1 121 ALA 121 121  ?   ?   ?   A . n 
A 1 122 GLU 122 122  ?   ?   ?   A . n 
A 1 123 LEU 123 123  ?   ?   ?   A . n 
A 1 124 ALA 124 124  ?   ?   ?   A . n 
A 1 125 GLY 125 125  ?   ?   ?   A . n 
A 1 126 VAL 126 126  ?   ?   ?   A . n 
A 1 127 ILE 127 127  ?   ?   ?   A . n 
A 1 128 LYS 128 128  ?   ?   ?   A . n 
A 1 129 ARG 129 129  ?   ?   ?   A . n 
A 1 130 LEU 130 130  ?   ?   ?   A . n 
A 1 131 TRP 131 131  ?   ?   ?   A . n 
A 1 132 LYS 132 132  ?   ?   ?   A . n 
A 1 133 ASP 133 133  ?   ?   ?   A . n 
A 1 134 SER 134 134  ?   ?   ?   A . n 
A 1 135 GLY 135 135  ?   ?   ?   A . n 
A 1 136 VAL 136 136  ?   ?   ?   A . n 
A 1 137 GLN 137 137  ?   ?   ?   A . n 
A 1 138 ALA 138 138  ?   ?   ?   A . n 
A 1 139 CYS 139 139  ?   ?   ?   A . n 
A 1 140 PHE 140 140  ?   ?   ?   A . n 
A 1 141 ASN 141 141  ?   ?   ?   A . n 
A 1 142 ARG 142 142  ?   ?   ?   A . n 
A 1 143 SER 143 143  ?   ?   ?   A . n 
A 1 144 ARG 144 144  ?   ?   ?   A . n 
A 1 145 GLU 145 145  ?   ?   ?   A . n 
A 1 146 TYR 146 146  ?   ?   ?   A . n 
A 1 147 GLN 147 147  ?   ?   ?   A . n 
A 1 148 LEU 148 148  ?   ?   ?   A . n 
A 1 149 ASN 149 149  ?   ?   ?   A . n 
A 1 150 ASP 150 150  ?   ?   ?   A . n 
A 1 151 SER 151 151  ?   ?   ?   A . n 
A 1 152 ALA 152 152  ?   ?   ?   A . n 
A 1 153 ALA 153 153  ?   ?   ?   A . n 
A 1 154 TYR 154 154  ?   ?   ?   A . n 
A 1 155 TYR 155 155  ?   ?   ?   A . n 
A 1 156 LEU 156 156  ?   ?   ?   A . n 
A 1 157 ASN 157 157  ?   ?   ?   A . n 
A 1 158 ASP 158 158  ?   ?   ?   A . n 
A 1 159 LEU 159 159  ?   ?   ?   A . n 
A 1 160 ASP 160 160  ?   ?   ?   A . n 
A 1 161 ARG 161 161  ?   ?   ?   A . n 
A 1 162 ILE 162 162  ?   ?   ?   A . n 
A 1 163 ALA 163 163  ?   ?   ?   A . n 
A 1 164 GLN 164 164  ?   ?   ?   A . n 
A 1 165 PRO 165 165  ?   ?   ?   A . n 
A 1 166 ASN 166 166  ?   ?   ?   A . n 
A 1 167 TYR 167 167  ?   ?   ?   A . n 
A 1 168 ILE 168 168  ?   ?   ?   A . n 
A 1 169 PRO 169 169  ?   ?   ?   A . n 
A 1 170 THR 170 170  ?   ?   ?   A . n 
A 1 171 GLN 171 171  ?   ?   ?   A . n 
A 1 172 GLN 172 172  ?   ?   ?   A . n 
A 1 173 ASP 173 173  ?   ?   ?   A . n 
A 1 174 VAL 174 174  ?   ?   ?   A . n 
A 1 175 LEU 175 175  ?   ?   ?   A . n 
A 1 176 ARG 176 176  ?   ?   ?   A . n 
A 1 177 THR 177 177  ?   ?   ?   A . n 
A 1 178 ARG 178 178  ?   ?   ?   A . n 
A 1 179 VAL 179 179  ?   ?   ?   A . n 
A 1 180 LYS 180 180  ?   ?   ?   A . n 
A 1 181 THR 181 181  ?   ?   ?   A . n 
A 1 182 THR 182 182  182 THR THR A . n 
A 1 183 GLY 183 183  183 GLY GLY A . n 
A 1 184 ILE 184 184  184 ILE ILE A . n 
A 1 185 VAL 185 185  185 VAL VAL A . n 
A 1 186 GLU 186 186  186 GLU GLU A . n 
A 1 187 THR 187 187  187 THR THR A . n 
A 1 188 HIS 188 188  188 HIS HIS A . n 
A 1 189 PHE 189 189  189 PHE PHE A . n 
A 1 190 THR 190 190  190 THR THR A . n 
A 1 191 PHE 191 191  191 PHE PHE A . n 
A 1 192 LYS 192 192  192 LYS LYS A . n 
A 1 193 ASP 193 193  193 ASP ASP A . n 
A 1 194 LEU 194 194  194 LEU LEU A . n 
A 1 195 HIS 195 195  195 HIS HIS A . n 
A 1 196 PHE 196 196  196 PHE PHE A . n 
A 1 197 LYS 197 197  197 LYS LYS A . n 
A 1 198 MET 198 198  198 MET MET A . n 
A 1 199 PHE 199 199  199 PHE PHE A . n 
A 1 200 ASP 200 200  200 ASP ASP A . n 
A 1 201 VAL 201 201  201 VAL VAL A . n 
A 1 202 GLY 202 202  202 GLY GLY A . n 
A 1 203 GLY 203 203  203 GLY GLY A . n 
A 1 204 GLN 204 204  204 GLN GLN A . n 
A 1 205 ARG 205 205  205 ARG ARG A . n 
A 1 206 SER 206 206  206 SER SER A . n 
A 1 207 GLU 207 207  207 GLU GLU A . n 
A 1 208 ARG 208 208  208 ARG ARG A . n 
A 1 209 LYS 209 209  209 LYS LYS A . n 
A 1 210 LYS 210 210  210 LYS LYS A . n 
A 1 211 TRP 211 211  211 TRP TRP A . n 
A 1 212 ILE 212 212  212 ILE ILE A . n 
A 1 213 HIS 213 213  213 HIS HIS A . n 
A 1 214 CYS 214 214  214 CYS CYS A . n 
A 1 215 PHE 215 215  215 PHE PHE A . n 
A 1 216 GLU 216 216  216 GLU GLU A . n 
A 1 217 GLY 217 217  217 GLY GLY A . n 
A 1 218 VAL 218 218  218 VAL VAL A . n 
A 1 219 THR 219 219  219 THR THR A . n 
A 1 220 ALA 220 220  220 ALA ALA A . n 
A 1 221 ILE 221 221  221 ILE ILE A . n 
A 1 222 ILE 222 222  222 ILE ILE A . n 
A 1 223 PHE 223 223  223 PHE PHE A . n 
A 1 224 CYS 224 224  224 CYS CYS A . n 
A 1 225 VAL 225 225  225 VAL VAL A . n 
A 1 226 ALA 226 226  226 ALA ALA A . n 
A 1 227 LEU 227 227  227 LEU LEU A . n 
A 1 228 SER 228 228  228 SER SER A . n 
A 1 229 ASP 229 229  229 ASP ASP A . n 
A 1 230 TYR 230 230  230 TYR TYR A . n 
A 1 231 ASP 231 231  231 ASP ASP A . n 
A 1 232 LEU 232 232  232 LEU LEU A . n 
A 1 233 VAL 233 233  233 VAL VAL A . n 
A 1 234 LEU 234 234  234 LEU LEU A . n 
A 1 235 ALA 235 235  ?   ?   ?   A . n 
A 1 236 GLU 236 236  ?   ?   ?   A . n 
A 1 237 ASP 237 237  ?   ?   ?   A . n 
A 1 238 GLU 238 238  ?   ?   ?   A . n 
A 1 239 GLU 239 239  ?   ?   ?   A . n 
A 1 240 MET 240 240  240 MET MET A . n 
A 1 241 ASN 241 241  241 ASN ASN A . n 
A 1 242 ARG 242 242  242 ARG ARG A . n 
A 1 243 MET 243 243  243 MET MET A . n 
A 1 244 HIS 244 244  244 HIS HIS A . n 
A 1 245 GLU 245 245  245 GLU GLU A . n 
A 1 246 SER 246 246  246 SER SER A . n 
A 1 247 MET 247 247  247 MET MET A . n 
A 1 248 LYS 248 248  248 LYS LYS A . n 
A 1 249 LEU 249 249  249 LEU LEU A . n 
A 1 250 PHE 250 250  250 PHE PHE A . n 
A 1 251 ASP 251 251  251 ASP ASP A . n 
A 1 252 SER 252 252  252 SER SER A . n 
A 1 253 ILE 253 253  253 ILE ILE A . n 
A 1 254 CYS 254 254  254 CYS CYS A . n 
A 1 255 ASN 255 255  255 ASN ASN A . n 
A 1 256 ASN 256 256  256 ASN ASN A . n 
A 1 257 LYS 257 257  257 LYS LYS A . n 
A 1 258 TRP 258 258  258 TRP TRP A . n 
A 1 259 PHE 259 259  259 PHE PHE A . n 
A 1 260 THR 260 260  260 THR THR A . n 
A 1 261 ASP 261 261  261 ASP ASP A . n 
A 1 262 THR 262 262  262 THR THR A . n 
A 1 263 SER 263 263  263 SER SER A . n 
A 1 264 ILE 264 264  264 ILE ILE A . n 
A 1 265 ILE 265 265  265 ILE ILE A . n 
A 1 266 LEU 266 266  266 LEU LEU A . n 
A 1 267 PHE 267 267  267 PHE PHE A . n 
A 1 268 LEU 268 268  268 LEU LEU A . n 
A 1 269 ASN 269 269  269 ASN ASN A . n 
A 1 270 LYS 270 270  270 LYS LYS A . n 
A 1 271 LYS 271 271  271 LYS LYS A . n 
A 1 272 ASP 272 272  272 ASP ASP A . n 
A 1 273 LEU 273 273  273 LEU LEU A . n 
A 1 274 PHE 274 274  274 PHE PHE A . n 
A 1 275 GLU 275 275  275 GLU GLU A . n 
A 1 276 GLU 276 276  276 GLU GLU A . n 
A 1 277 LYS 277 277  277 LYS LYS A . n 
A 1 278 ILE 278 278  278 ILE ILE A . n 
A 1 279 LYS 279 279  279 LYS LYS A . n 
A 1 280 LYS 280 280  280 LYS LYS A . n 
A 1 281 SER 281 281  281 SER SER A . n 
A 1 282 PRO 282 282  282 PRO PRO A . n 
A 1 283 LEU 283 283  283 LEU LEU A . n 
A 1 284 THR 284 284  284 THR THR A . n 
A 1 285 ILE 285 285  285 ILE ILE A . n 
A 1 286 CYS 286 286  286 CYS CYS A . n 
A 1 287 TYR 287 287  287 TYR TYR A . n 
A 1 288 PRO 288 288  288 PRO PRO A . n 
A 1 289 GLU 289 289  289 GLU GLU A . n 
A 1 290 TYR 290 290  290 TYR TYR A . n 
A 1 291 ALA 291 291  291 ALA ALA A . n 
A 1 292 GLY 292 292  292 GLY GLY A . n 
A 1 293 SER 293 293  293 SER SER A . n 
A 1 294 ASN 294 294  294 ASN ASN A . n 
A 1 295 THR 295 295  295 THR THR A . n 
A 1 296 TYR 296 296  296 TYR TYR A . n 
A 1 297 GLU 297 297  297 GLU GLU A . n 
A 1 298 GLU 298 298  298 GLU GLU A . n 
A 1 299 ALA 299 299  299 ALA ALA A . n 
A 1 300 ALA 300 300  300 ALA ALA A . n 
A 1 301 ALA 301 301  301 ALA ALA A . n 
A 1 302 TYR 302 302  302 TYR TYR A . n 
A 1 303 ILE 303 303  303 ILE ILE A . n 
A 1 304 GLN 304 304  304 GLN GLN A . n 
A 1 305 CYS 305 305  305 CYS CYS A . n 
A 1 306 GLN 306 306  306 GLN GLN A . n 
A 1 307 PHE 307 307  307 PHE PHE A . n 
A 1 308 GLU 308 308  308 GLU GLU A . n 
A 1 309 ASP 309 309  309 ASP ASP A . n 
A 1 310 LEU 310 310  310 LEU LEU A . n 
A 1 311 ASN 311 311  311 ASN ASN A . n 
A 1 312 LYS 312 312  312 LYS LYS A . n 
A 1 313 ARG 313 313  313 ARG ARG A . n 
A 1 314 LYS 314 314  314 LYS LYS A . n 
A 1 315 ASP 315 315  315 ASP ASP A . n 
A 1 316 THR 316 316  316 THR THR A . n 
A 1 317 LYS 317 317  317 LYS LYS A . n 
A 1 318 GLU 318 318  318 GLU GLU A . n 
A 1 319 ILE 319 319  319 ILE ILE A . n 
A 1 320 TYR 320 320  320 TYR TYR A . n 
A 1 321 THR 321 321  321 THR THR A . n 
A 1 322 HIS 322 322  322 HIS HIS A . n 
A 1 323 PHE 323 323  323 PHE PHE A . n 
A 1 324 THR 324 324  324 THR THR A . n 
A 1 325 CYS 325 325  325 CYS CYS A . n 
A 1 326 ALA 326 326  326 ALA ALA A . n 
A 1 327 THR 327 327  327 THR THR A . n 
A 1 328 ASP 328 328  328 ASP ASP A . n 
A 1 329 THR 329 329  329 THR THR A . n 
A 1 330 LYS 330 330  330 LYS LYS A . n 
A 1 331 ASN 331 331  331 ASN ASN A . n 
A 1 332 VAL 332 332  332 VAL VAL A . n 
A 1 333 GLN 333 333  333 GLN GLN A . n 
A 1 334 PHE 334 334  334 PHE PHE A . n 
A 1 335 VAL 335 335  335 VAL VAL A . n 
A 1 336 PHE 336 336  336 PHE PHE A . n 
A 1 337 ASP 337 337  337 ASP ASP A . n 
A 1 338 ALA 338 338  338 ALA ALA A . n 
A 1 339 VAL 339 339  339 VAL VAL A . n 
A 1 340 THR 340 340  340 THR THR A . n 
A 1 341 ASP 341 341  341 ASP ASP A . n 
A 1 342 VAL 342 342  342 VAL VAL A . n 
A 1 343 ILE 343 343  343 ILE ILE A . n 
A 1 344 ILE 344 344  344 ILE ILE A . n 
A 1 345 LYS 345 345  345 LYS LYS A . n 
A 1 346 ASN 346 346  346 ASN ASN A . n 
A 1 347 ASN 347 347  347 ASN ASN A . n 
A 1 348 LEU 348 348  348 LEU LEU A . n 
A 1 349 LYS 349 349  349 LYS LYS A . n 
A 1 350 ASP 350 350  350 ASP ASP A . n 
A 1 351 CYS 351 351  351 CYS CYS A . n 
A 1 352 GLY 352 352  352 GLY GLY A . n 
A 1 353 LEU 353 353  353 LEU LEU A . n 
A 1 354 PHE 354 354  354 PHE PHE A . n 
B 2 1   MET 1   -10  ?   ?   ?   B . n 
B 2 2   HIS 2   -9   ?   ?   ?   B . n 
B 2 3   HIS 3   -8   ?   ?   ?   B . n 
B 2 4   HIS 4   -7   ?   ?   ?   B . n 
B 2 5   HIS 5   -6   ?   ?   ?   B . n 
B 2 6   HIS 6   -5   ?   ?   ?   B . n 
B 2 7   HIS 7   -4   ?   ?   ?   B . n 
B 2 8   GLY 8   -3   ?   ?   ?   B . n 
B 2 9   SER 9   -2   ?   ?   ?   B . n 
B 2 10  LEU 10  -1   ?   ?   ?   B . n 
B 2 11  LEU 11  0    ?   ?   ?   B . n 
B 2 12  GLN 12  1    ?   ?   ?   B . n 
B 2 13  SER 13  2    ?   ?   ?   B . n 
B 2 14  GLU 14  3    ?   ?   ?   B . n 
B 2 15  LEU 15  4    4   LEU LEU B . n 
B 2 16  ASP 16  5    5   ASP ASP B . n 
B 2 17  GLN 17  6    6   GLN GLN B . n 
B 2 18  LEU 18  7    7   LEU LEU B . n 
B 2 19  ARG 19  8    8   ARG ARG B . n 
B 2 20  GLN 20  9    9   GLN GLN B . n 
B 2 21  GLU 21  10   10  GLU GLU B . n 
B 2 22  ALA 22  11   11  ALA ALA B . n 
B 2 23  GLU 23  12   12  GLU GLU B . n 
B 2 24  GLN 24  13   13  GLN GLN B . n 
B 2 25  LEU 25  14   14  LEU LEU B . n 
B 2 26  LYS 26  15   15  LYS LYS B . n 
B 2 27  ASN 27  16   16  ASN ASN B . n 
B 2 28  GLN 28  17   17  GLN GLN B . n 
B 2 29  ILE 29  18   18  ILE ILE B . n 
B 2 30  ARG 30  19   19  ARG ARG B . n 
B 2 31  ASP 31  20   20  ASP ASP B . n 
B 2 32  ALA 32  21   21  ALA ALA B . n 
B 2 33  ARG 33  22   22  ARG ARG B . n 
B 2 34  LYS 34  23   23  LYS LYS B . n 
B 2 35  ALA 35  24   24  ALA ALA B . n 
B 2 36  CYS 36  25   25  CYS CYS B . n 
B 2 37  ALA 37  26   26  ALA ALA B . n 
B 2 38  ASP 38  27   27  ASP ASP B . n 
B 2 39  ALA 39  28   28  ALA ALA B . n 
B 2 40  THR 40  29   29  THR THR B . n 
B 2 41  LEU 41  30   30  LEU LEU B . n 
B 2 42  SER 42  31   31  SER SER B . n 
B 2 43  GLN 43  32   32  GLN GLN B . n 
B 2 44  ILE 44  33   33  ILE ILE B . n 
B 2 45  THR 45  34   34  THR THR B . n 
B 2 46  ASN 46  35   35  ASN ASN B . n 
B 2 47  ASN 47  36   36  ASN ASN B . n 
B 2 48  ILE 48  37   37  ILE ILE B . n 
B 2 49  ASP 49  38   38  ASP ASP B . n 
B 2 50  PRO 50  39   39  PRO PRO B . n 
B 2 51  VAL 51  40   40  VAL VAL B . n 
B 2 52  GLY 52  41   41  GLY GLY B . n 
B 2 53  ARG 53  42   42  ARG ARG B . n 
B 2 54  ILE 54  43   43  ILE ILE B . n 
B 2 55  GLN 55  44   44  GLN GLN B . n 
B 2 56  MET 56  45   45  MET MET B . n 
B 2 57  ARG 57  46   46  ARG ARG B . n 
B 2 58  THR 58  47   47  THR THR B . n 
B 2 59  ARG 59  48   48  ARG ARG B . n 
B 2 60  ARG 60  49   49  ARG ARG B . n 
B 2 61  THR 61  50   50  THR THR B . n 
B 2 62  LEU 62  51   51  LEU LEU B . n 
B 2 63  ARG 63  52   52  ARG ARG B . n 
B 2 64  GLY 64  53   53  GLY GLY B . n 
B 2 65  HIS 65  54   54  HIS HIS B . n 
B 2 66  LEU 66  55   55  LEU LEU B . n 
B 2 67  ALA 67  56   56  ALA ALA B . n 
B 2 68  LYS 68  57   57  LYS LYS B . n 
B 2 69  ILE 69  58   58  ILE ILE B . n 
B 2 70  TYR 70  59   59  TYR TYR B . n 
B 2 71  ALA 71  60   60  ALA ALA B . n 
B 2 72  MET 72  61   61  MET MET B . n 
B 2 73  HIS 73  62   62  HIS HIS B . n 
B 2 74  TRP 74  63   63  TRP TRP B . n 
B 2 75  GLY 75  64   64  GLY GLY B . n 
B 2 76  THR 76  65   65  THR THR B . n 
B 2 77  ASP 77  66   66  ASP ASP B . n 
B 2 78  SER 78  67   67  SER SER B . n 
B 2 79  ARG 79  68   68  ARG ARG B . n 
B 2 80  LEU 80  69   69  LEU LEU B . n 
B 2 81  LEU 81  70   70  LEU LEU B . n 
B 2 82  VAL 82  71   71  VAL VAL B . n 
B 2 83  SER 83  72   72  SER SER B . n 
B 2 84  ALA 84  73   73  ALA ALA B . n 
B 2 85  SER 85  74   74  SER SER B . n 
B 2 86  GLN 86  75   75  GLN GLN B . n 
B 2 87  ASP 87  76   76  ASP ASP B . n 
B 2 88  GLY 88  77   77  GLY GLY B . n 
B 2 89  LYS 89  78   78  LYS LYS B . n 
B 2 90  LEU 90  79   79  LEU LEU B . n 
B 2 91  ILE 91  80   80  ILE ILE B . n 
B 2 92  ILE 92  81   81  ILE ILE B . n 
B 2 93  TRP 93  82   82  TRP TRP B . n 
B 2 94  ASP 94  83   83  ASP ASP B . n 
B 2 95  SER 95  84   84  SER SER B . n 
B 2 96  TYR 96  85   85  TYR TYR B . n 
B 2 97  THR 97  86   86  THR THR B . n 
B 2 98  THR 98  87   87  THR THR B . n 
B 2 99  ASN 99  88   88  ASN ASN B . n 
B 2 100 LYS 100 89   89  LYS LYS B . n 
B 2 101 VAL 101 90   90  VAL VAL B . n 
B 2 102 HIS 102 91   91  HIS HIS B . n 
B 2 103 ALA 103 92   92  ALA ALA B . n 
B 2 104 ILE 104 93   93  ILE ILE B . n 
B 2 105 PRO 105 94   94  PRO PRO B . n 
B 2 106 LEU 106 95   95  LEU LEU B . n 
B 2 107 ARG 107 96   96  ARG ARG B . n 
B 2 108 SER 108 97   97  SER SER B . n 
B 2 109 SER 109 98   98  SER SER B . n 
B 2 110 TRP 110 99   99  TRP TRP B . n 
B 2 111 VAL 111 100  100 VAL VAL B . n 
B 2 112 MET 112 101  101 MET MET B . n 
B 2 113 THR 113 102  102 THR THR B . n 
B 2 114 CYS 114 103  103 CYS CYS B . n 
B 2 115 ALA 115 104  104 ALA ALA B . n 
B 2 116 TYR 116 105  105 TYR TYR B . n 
B 2 117 ALA 117 106  106 ALA ALA B . n 
B 2 118 PRO 118 107  107 PRO PRO B . n 
B 2 119 SER 119 108  108 SER SER B . n 
B 2 120 GLY 120 109  109 GLY GLY B . n 
B 2 121 ASN 121 110  110 ASN ASN B . n 
B 2 122 TYR 122 111  111 TYR TYR B . n 
B 2 123 VAL 123 112  112 VAL VAL B . n 
B 2 124 ALA 124 113  113 ALA ALA B . n 
B 2 125 CYS 125 114  114 CYS CYS B . n 
B 2 126 GLY 126 115  115 GLY GLY B . n 
B 2 127 GLY 127 116  116 GLY GLY B . n 
B 2 128 LEU 128 117  117 LEU LEU B . n 
B 2 129 ASP 129 118  118 ASP ASP B . n 
B 2 130 ASN 130 119  119 ASN ASN B . n 
B 2 131 ILE 131 120  120 ILE ILE B . n 
B 2 132 CYS 132 121  121 CYS CYS B . n 
B 2 133 SER 133 122  122 SER SER B . n 
B 2 134 ILE 134 123  123 ILE ILE B . n 
B 2 135 TYR 135 124  124 TYR TYR B . n 
B 2 136 ASN 136 125  125 ASN ASN B . n 
B 2 137 LEU 137 126  126 LEU LEU B . n 
B 2 138 LYS 138 127  127 LYS LYS B . n 
B 2 139 THR 139 128  128 THR THR B . n 
B 2 140 ARG 140 129  129 ARG ARG B . n 
B 2 141 GLU 141 130  130 GLU GLU B . n 
B 2 142 GLY 142 131  131 GLY GLY B . n 
B 2 143 ASN 143 132  132 ASN ASN B . n 
B 2 144 VAL 144 133  133 VAL VAL B . n 
B 2 145 ARG 145 134  134 ARG ARG B . n 
B 2 146 VAL 146 135  135 VAL VAL B . n 
B 2 147 SER 147 136  136 SER SER B . n 
B 2 148 ARG 148 137  137 ARG ARG B . n 
B 2 149 GLU 149 138  138 GLU GLU B . n 
B 2 150 LEU 150 139  139 LEU LEU B . n 
B 2 151 ALA 151 140  140 ALA ALA B . n 
B 2 152 GLY 152 141  141 GLY GLY B . n 
B 2 153 HIS 153 142  142 HIS HIS B . n 
B 2 154 THR 154 143  143 THR THR B . n 
B 2 155 GLY 155 144  144 GLY GLY B . n 
B 2 156 TYR 156 145  145 TYR TYR B . n 
B 2 157 LEU 157 146  146 LEU LEU B . n 
B 2 158 SER 158 147  147 SER SER B . n 
B 2 159 CYS 159 148  148 CYS CYS B . n 
B 2 160 CYS 160 149  149 CYS CYS B . n 
B 2 161 ARG 161 150  150 ARG ARG B . n 
B 2 162 PHE 162 151  151 PHE PHE B . n 
B 2 163 LEU 163 152  152 LEU LEU B . n 
B 2 164 ASP 164 153  153 ASP ASP B . n 
B 2 165 ASP 165 154  154 ASP ASP B . n 
B 2 166 ASN 166 155  155 ASN ASN B . n 
B 2 167 GLN 167 156  156 GLN GLN B . n 
B 2 168 ILE 168 157  157 ILE ILE B . n 
B 2 169 VAL 169 158  158 VAL VAL B . n 
B 2 170 THR 170 159  159 THR THR B . n 
B 2 171 SER 171 160  160 SER SER B . n 
B 2 172 SER 172 161  161 SER SER B . n 
B 2 173 GLY 173 162  162 GLY GLY B . n 
B 2 174 ASP 174 163  163 ASP ASP B . n 
B 2 175 THR 175 164  164 THR THR B . n 
B 2 176 THR 176 165  165 THR THR B . n 
B 2 177 CYS 177 166  166 CYS CYS B . n 
B 2 178 ALA 178 167  167 ALA ALA B . n 
B 2 179 LEU 179 168  168 LEU LEU B . n 
B 2 180 TRP 180 169  169 TRP TRP B . n 
B 2 181 ASP 181 170  170 ASP ASP B . n 
B 2 182 ILE 182 171  171 ILE ILE B . n 
B 2 183 GLU 183 172  172 GLU GLU B . n 
B 2 184 THR 184 173  173 THR THR B . n 
B 2 185 GLY 185 174  174 GLY GLY B . n 
B 2 186 GLN 186 175  175 GLN GLN B . n 
B 2 187 GLN 187 176  176 GLN GLN B . n 
B 2 188 THR 188 177  177 THR THR B . n 
B 2 189 THR 189 178  178 THR THR B . n 
B 2 190 THR 190 179  179 THR THR B . n 
B 2 191 PHE 191 180  180 PHE PHE B . n 
B 2 192 THR 192 181  181 THR THR B . n 
B 2 193 GLY 193 182  182 GLY GLY B . n 
B 2 194 HIS 194 183  183 HIS HIS B . n 
B 2 195 THR 195 184  184 THR THR B . n 
B 2 196 GLY 196 185  185 GLY GLY B . n 
B 2 197 ASP 197 186  186 ASP ASP B . n 
B 2 198 VAL 198 187  187 VAL VAL B . n 
B 2 199 MET 199 188  188 MET MET B . n 
B 2 200 SER 200 189  189 SER SER B . n 
B 2 201 LEU 201 190  190 LEU LEU B . n 
B 2 202 SER 202 191  191 SER SER B . n 
B 2 203 LEU 203 192  192 LEU LEU B . n 
B 2 204 ALA 204 193  193 ALA ALA B . n 
B 2 205 PRO 205 194  194 PRO PRO B . n 
B 2 206 ASP 206 195  195 ASP ASP B . n 
B 2 207 THR 207 196  196 THR THR B . n 
B 2 208 ARG 208 197  197 ARG ARG B . n 
B 2 209 LEU 209 198  198 LEU LEU B . n 
B 2 210 PHE 210 199  199 PHE PHE B . n 
B 2 211 VAL 211 200  200 VAL VAL B . n 
B 2 212 SER 212 201  201 SER SER B . n 
B 2 213 GLY 213 202  202 GLY GLY B . n 
B 2 214 ALA 214 203  203 ALA ALA B . n 
B 2 215 CYS 215 204  204 CYS CYS B . n 
B 2 216 ASP 216 205  205 ASP ASP B . n 
B 2 217 ALA 217 206  206 ALA ALA B . n 
B 2 218 SER 218 207  207 SER SER B . n 
B 2 219 ALA 219 208  208 ALA ALA B . n 
B 2 220 LYS 220 209  209 LYS LYS B . n 
B 2 221 LEU 221 210  210 LEU LEU B . n 
B 2 222 TRP 222 211  211 TRP TRP B . n 
B 2 223 ASP 223 212  212 ASP ASP B . n 
B 2 224 VAL 224 213  213 VAL VAL B . n 
B 2 225 ARG 225 214  214 ARG ARG B . n 
B 2 226 GLU 226 215  215 GLU GLU B . n 
B 2 227 GLY 227 216  216 GLY GLY B . n 
B 2 228 MET 228 217  217 MET MET B . n 
B 2 229 CYS 229 218  218 CYS CYS B . n 
B 2 230 ARG 230 219  219 ARG ARG B . n 
B 2 231 GLN 231 220  220 GLN GLN B . n 
B 2 232 THR 232 221  221 THR THR B . n 
B 2 233 PHE 233 222  222 PHE PHE B . n 
B 2 234 THR 234 223  223 THR THR B . n 
B 2 235 GLY 235 224  224 GLY GLY B . n 
B 2 236 HIS 236 225  225 HIS HIS B . n 
B 2 237 GLU 237 226  226 GLU GLU B . n 
B 2 238 SER 238 227  227 SER SER B . n 
B 2 239 ASP 239 228  228 ASP ASP B . n 
B 2 240 ILE 240 229  229 ILE ILE B . n 
B 2 241 ASN 241 230  230 ASN ASN B . n 
B 2 242 ALA 242 231  231 ALA ALA B . n 
B 2 243 ILE 243 232  232 ILE ILE B . n 
B 2 244 CYS 244 233  233 CYS CYS B . n 
B 2 245 PHE 245 234  234 PHE PHE B . n 
B 2 246 PHE 246 235  235 PHE PHE B . n 
B 2 247 PRO 247 236  236 PRO PRO B . n 
B 2 248 ASN 248 237  237 ASN ASN B . n 
B 2 249 GLY 249 238  238 GLY GLY B . n 
B 2 250 ASN 250 239  239 ASN ASN B . n 
B 2 251 ALA 251 240  240 ALA ALA B . n 
B 2 252 PHE 252 241  241 PHE PHE B . n 
B 2 253 ALA 253 242  242 ALA ALA B . n 
B 2 254 THR 254 243  243 THR THR B . n 
B 2 255 GLY 255 244  244 GLY GLY B . n 
B 2 256 SER 256 245  245 SER SER B . n 
B 2 257 ASP 257 246  246 ASP ASP B . n 
B 2 258 ASP 258 247  247 ASP ASP B . n 
B 2 259 ALA 259 248  248 ALA ALA B . n 
B 2 260 THR 260 249  249 THR THR B . n 
B 2 261 CYS 261 250  250 CYS CYS B . n 
B 2 262 ARG 262 251  251 ARG ARG B . n 
B 2 263 LEU 263 252  252 LEU LEU B . n 
B 2 264 PHE 264 253  253 PHE PHE B . n 
B 2 265 ASP 265 254  254 ASP ASP B . n 
B 2 266 LEU 266 255  255 LEU LEU B . n 
B 2 267 ARG 267 256  256 ARG ARG B . n 
B 2 268 ALA 268 257  257 ALA ALA B . n 
B 2 269 ASP 269 258  258 ASP ASP B . n 
B 2 270 GLN 270 259  259 GLN GLN B . n 
B 2 271 GLU 271 260  260 GLU GLU B . n 
B 2 272 LEU 272 261  261 LEU LEU B . n 
B 2 273 MET 273 262  262 MET MET B . n 
B 2 274 THR 274 263  263 THR THR B . n 
B 2 275 TYR 275 264  264 TYR TYR B . n 
B 2 276 SER 276 265  265 SER SER B . n 
B 2 277 HIS 277 266  266 HIS HIS B . n 
B 2 278 ASP 278 267  267 ASP ASP B . n 
B 2 279 ASN 279 268  268 ASN ASN B . n 
B 2 280 ILE 280 269  269 ILE ILE B . n 
B 2 281 ILE 281 270  270 ILE ILE B . n 
B 2 282 CYS 282 271  271 CYS CYS B . n 
B 2 283 GLY 283 272  272 GLY GLY B . n 
B 2 284 ILE 284 273  273 ILE ILE B . n 
B 2 285 THR 285 274  274 THR THR B . n 
B 2 286 SER 286 275  275 SER SER B . n 
B 2 287 VAL 287 276  276 VAL VAL B . n 
B 2 288 SER 288 277  277 SER SER B . n 
B 2 289 PHE 289 278  278 PHE PHE B . n 
B 2 290 SER 290 279  279 SER SER B . n 
B 2 291 LYS 291 280  280 LYS LYS B . n 
B 2 292 SER 292 281  281 SER SER B . n 
B 2 293 GLY 293 282  282 GLY GLY B . n 
B 2 294 ARG 294 283  283 ARG ARG B . n 
B 2 295 LEU 295 284  284 LEU LEU B . n 
B 2 296 LEU 296 285  285 LEU LEU B . n 
B 2 297 LEU 297 286  286 LEU LEU B . n 
B 2 298 ALA 298 287  287 ALA ALA B . n 
B 2 299 GLY 299 288  288 GLY GLY B . n 
B 2 300 TYR 300 289  289 TYR TYR B . n 
B 2 301 ASP 301 290  290 ASP ASP B . n 
B 2 302 ASP 302 291  291 ASP ASP B . n 
B 2 303 PHE 303 292  292 PHE PHE B . n 
B 2 304 ASN 304 293  293 ASN ASN B . n 
B 2 305 CYS 305 294  294 CYS CYS B . n 
B 2 306 ASN 306 295  295 ASN ASN B . n 
B 2 307 VAL 307 296  296 VAL VAL B . n 
B 2 308 TRP 308 297  297 TRP TRP B . n 
B 2 309 ASP 309 298  298 ASP ASP B . n 
B 2 310 ALA 310 299  299 ALA ALA B . n 
B 2 311 LEU 311 300  300 LEU LEU B . n 
B 2 312 LYS 312 301  301 LYS LYS B . n 
B 2 313 ALA 313 302  302 ALA ALA B . n 
B 2 314 ASP 314 303  303 ASP ASP B . n 
B 2 315 ARG 315 304  304 ARG ARG B . n 
B 2 316 ALA 316 305  305 ALA ALA B . n 
B 2 317 GLY 317 306  306 GLY GLY B . n 
B 2 318 VAL 318 307  307 VAL VAL B . n 
B 2 319 LEU 319 308  308 LEU LEU B . n 
B 2 320 ALA 320 309  309 ALA ALA B . n 
B 2 321 GLY 321 310  310 GLY GLY B . n 
B 2 322 HIS 322 311  311 HIS HIS B . n 
B 2 323 ASP 323 312  312 ASP ASP B . n 
B 2 324 ASN 324 313  313 ASN ASN B . n 
B 2 325 ARG 325 314  314 ARG ARG B . n 
B 2 326 VAL 326 315  315 VAL VAL B . n 
B 2 327 SER 327 316  316 SER SER B . n 
B 2 328 CYS 328 317  317 CYS CYS B . n 
B 2 329 LEU 329 318  318 LEU LEU B . n 
B 2 330 GLY 330 319  319 GLY GLY B . n 
B 2 331 VAL 331 320  320 VAL VAL B . n 
B 2 332 THR 332 321  321 THR THR B . n 
B 2 333 ASP 333 322  322 ASP ASP B . n 
B 2 334 ASP 334 323  323 ASP ASP B . n 
B 2 335 GLY 335 324  324 GLY GLY B . n 
B 2 336 MET 336 325  325 MET MET B . n 
B 2 337 ALA 337 326  326 ALA ALA B . n 
B 2 338 VAL 338 327  327 VAL VAL B . n 
B 2 339 ALA 339 328  328 ALA ALA B . n 
B 2 340 THR 340 329  329 THR THR B . n 
B 2 341 GLY 341 330  330 GLY GLY B . n 
B 2 342 SER 342 331  331 SER SER B . n 
B 2 343 TRP 343 332  332 TRP TRP B . n 
B 2 344 ASP 344 333  333 ASP ASP B . n 
B 2 345 SER 345 334  334 SER SER B . n 
B 2 346 PHE 346 335  335 PHE PHE B . n 
B 2 347 LEU 347 336  336 LEU LEU B . n 
B 2 348 LYS 348 337  337 LYS LYS B . n 
B 2 349 ILE 349 338  338 ILE ILE B . n 
B 2 350 TRP 350 339  339 TRP TRP B . n 
B 2 351 ASN 351 340  340 ASN ASN B . n 
B 2 352 GLY 352 341  ?   ?   ?   B . n 
B 2 353 SER 353 342  ?   ?   ?   B . n 
B 2 354 SER 354 343  ?   ?   ?   B . n 
B 2 355 GLY 355 344  ?   ?   ?   B . n 
B 2 356 GLY 356 345  ?   ?   ?   B . n 
B 2 357 GLY 357 346  ?   ?   ?   B . n 
B 2 358 GLY 358 347  ?   ?   ?   B . n 
B 2 359 SER 359 348  ?   ?   ?   B . n 
B 2 360 GLY 360 349  ?   ?   ?   B . n 
B 2 361 GLY 361 350  ?   ?   ?   B . n 
B 2 362 GLY 362 351  ?   ?   ?   B . n 
B 2 363 GLY 363 352  ?   ?   ?   B . n 
B 2 364 SER 364 353  ?   ?   ?   B . n 
B 2 365 SER 365 354  ?   ?   ?   B . n 
B 2 366 GLY 366 355  ?   ?   ?   B . n 
B 2 367 VAL 367 356  ?   ?   ?   B . n 
B 2 368 SER 368 357  ?   ?   ?   B . n 
B 2 369 GLY 369 358  ?   ?   ?   B . n 
B 2 370 TRP 370 359  ?   ?   ?   B . n 
B 2 371 ARG 371 360  ?   ?   ?   B . n 
B 2 372 LEU 372 361  ?   ?   ?   B . n 
B 2 373 PHE 373 362  ?   ?   ?   B . n 
B 2 374 LYS 374 363  ?   ?   ?   B . n 
B 2 375 LYS 375 364  ?   ?   ?   B . n 
B 2 376 ILE 376 365  ?   ?   ?   B . n 
B 2 377 SER 377 366  ?   ?   ?   B . n 
C 3 1   MET 1   1    ?   ?   ?   G . n 
C 3 2   ALA 2   2    ?   ?   ?   G . n 
C 3 3   SER 3   3    ?   ?   ?   G . n 
C 3 4   ASN 4   4    ?   ?   ?   G . n 
C 3 5   ASN 5   5    ?   ?   ?   G . n 
C 3 6   THR 6   6    ?   ?   ?   G . n 
C 3 7   ALA 7   7    7   ALA ALA G . n 
C 3 8   SER 8   8    8   SER SER G . n 
C 3 9   ILE 9   9    9   ILE ILE G . n 
C 3 10  ALA 10  10   10  ALA ALA G . n 
C 3 11  GLN 11  11   11  GLN GLN G . n 
C 3 12  ALA 12  12   12  ALA ALA G . n 
C 3 13  ARG 13  13   13  ARG ARG G . n 
C 3 14  LYS 14  14   14  LYS LYS G . n 
C 3 15  LEU 15  15   15  LEU LEU G . n 
C 3 16  VAL 16  16   16  VAL VAL G . n 
C 3 17  GLU 17  17   17  GLU GLU G . n 
C 3 18  GLN 18  18   18  GLN GLN G . n 
C 3 19  LEU 19  19   19  LEU LEU G . n 
C 3 20  LYS 20  20   20  LYS LYS G . n 
C 3 21  MET 21  21   21  MET MET G . n 
C 3 22  GLU 22  22   22  GLU GLU G . n 
C 3 23  ALA 23  23   23  ALA ALA G . n 
C 3 24  ASN 24  24   24  ASN ASN G . n 
C 3 25  ILE 25  25   25  ILE ILE G . n 
C 3 26  ASP 26  26   26  ASP ASP G . n 
C 3 27  ARG 27  27   27  ARG ARG G . n 
C 3 28  ILE 28  28   28  ILE ILE G . n 
C 3 29  LYS 29  29   29  LYS LYS G . n 
C 3 30  VAL 30  30   30  VAL VAL G . n 
C 3 31  SER 31  31   31  SER SER G . n 
C 3 32  LYS 32  32   32  LYS LYS G . n 
C 3 33  ALA 33  33   33  ALA ALA G . n 
C 3 34  ALA 34  34   34  ALA ALA G . n 
C 3 35  ALA 35  35   35  ALA ALA G . n 
C 3 36  ASP 36  36   36  ASP ASP G . n 
C 3 37  LEU 37  37   37  LEU LEU G . n 
C 3 38  MET 38  38   38  MET MET G . n 
C 3 39  ALA 39  39   39  ALA ALA G . n 
C 3 40  TYR 40  40   40  TYR TYR G . n 
C 3 41  CYS 41  41   41  CYS CYS G . n 
C 3 42  GLU 42  42   42  GLU GLU G . n 
C 3 43  ALA 43  43   43  ALA ALA G . n 
C 3 44  HIS 44  44   44  HIS HIS G . n 
C 3 45  ALA 45  45   45  ALA ALA G . n 
C 3 46  LYS 46  46   46  LYS LYS G . n 
C 3 47  GLU 47  47   47  GLU GLU G . n 
C 3 48  ASP 48  48   48  ASP ASP G . n 
C 3 49  PRO 49  49   49  PRO PRO G . n 
C 3 50  LEU 50  50   50  LEU LEU G . n 
C 3 51  LEU 51  51   51  LEU LEU G . n 
C 3 52  THR 52  52   52  THR THR G . n 
C 3 53  PRO 53  53   53  PRO PRO G . n 
C 3 54  VAL 54  54   54  VAL VAL G . n 
C 3 55  PRO 55  55   55  PRO PRO G . n 
C 3 56  ALA 56  56   56  ALA ALA G . n 
C 3 57  SER 57  57   57  SER SER G . n 
C 3 58  GLU 58  58   58  GLU GLU G . n 
C 3 59  ASN 59  59   59  ASN ASN G . n 
C 3 60  PRO 60  60   60  PRO PRO G . n 
C 3 61  PHE 61  61   61  PHE PHE G . n 
C 3 62  ARG 62  62   62  ARG ARG G . n 
C 3 63  GLU 63  63   ?   ?   ?   G . n 
C 3 64  LYS 64  64   ?   ?   ?   G . n 
C 3 65  LYS 65  65   ?   ?   ?   G . n 
C 3 66  PHE 66  66   ?   ?   ?   G . n 
C 3 67  PHE 67  67   ?   ?   ?   G . n 
C 3 68  CYS 68  68   ?   ?   ?   G . n 
C 3 69  ALA 69  69   ?   ?   ?   G . n 
C 3 70  ILE 70  70   ?   ?   ?   G . n 
C 3 71  LEU 71  71   ?   ?   ?   G . n 
D 4 1   MET 1   -162 ?   ?   ?   R . n 
D 4 2   LYS 2   -161 ?   ?   ?   R . n 
D 4 3   THR 3   -160 ?   ?   ?   R . n 
D 4 4   ILE 4   -159 ?   ?   ?   R . n 
D 4 5   ILE 5   -158 ?   ?   ?   R . n 
D 4 6   ALA 6   -157 ?   ?   ?   R . n 
D 4 7   LEU 7   -156 ?   ?   ?   R . n 
D 4 8   SER 8   -155 ?   ?   ?   R . n 
D 4 9   TYR 9   -154 ?   ?   ?   R . n 
D 4 10  ILE 10  -153 ?   ?   ?   R . n 
D 4 11  PHE 11  -152 ?   ?   ?   R . n 
D 4 12  CYS 12  -151 ?   ?   ?   R . n 
D 4 13  LEU 13  -150 ?   ?   ?   R . n 
D 4 14  VAL 14  -149 ?   ?   ?   R . n 
D 4 15  PHE 15  -148 ?   ?   ?   R . n 
D 4 16  ALA 16  -147 ?   ?   ?   R . n 
D 4 17  ASP 17  -146 ?   ?   ?   R . n 
D 4 18  TYR 18  -145 ?   ?   ?   R . n 
D 4 19  LYS 19  -144 ?   ?   ?   R . n 
D 4 20  ASP 20  -143 ?   ?   ?   R . n 
D 4 21  ASP 21  -142 ?   ?   ?   R . n 
D 4 22  ASP 22  -141 ?   ?   ?   R . n 
D 4 23  ASP 23  -140 ?   ?   ?   R . n 
D 4 24  ALA 24  -139 ?   ?   ?   R . n 
D 4 25  GLY 25  -138 ?   ?   ?   R . n 
D 4 26  ARG 26  -137 ?   ?   ?   R . n 
D 4 27  ALA 27  -136 ?   ?   ?   R . n 
D 4 28  HIS 28  -135 ?   ?   ?   R . n 
D 4 29  HIS 29  -134 ?   ?   ?   R . n 
D 4 30  HIS 30  -133 ?   ?   ?   R . n 
D 4 31  HIS 31  -132 ?   ?   ?   R . n 
D 4 32  HIS 32  -131 ?   ?   ?   R . n 
D 4 33  HIS 33  -130 ?   ?   ?   R . n 
D 4 34  HIS 34  -129 ?   ?   ?   R . n 
D 4 35  HIS 35  -128 ?   ?   ?   R . n 
D 4 36  HIS 36  -127 ?   ?   ?   R . n 
D 4 37  HIS 37  -126 ?   ?   ?   R . n 
D 4 38  GLU 38  -125 ?   ?   ?   R . n 
D 4 39  ASN 39  -124 ?   ?   ?   R . n 
D 4 40  LEU 40  -123 ?   ?   ?   R . n 
D 4 41  TYR 41  -122 ?   ?   ?   R . n 
D 4 42  PHE 42  -121 ?   ?   ?   R . n 
D 4 43  GLN 43  -120 ?   ?   ?   R . n 
D 4 44  SER 44  -119 ?   ?   ?   R . n 
D 4 45  GLY 45  -118 ?   ?   ?   R . n 
D 4 46  ALA 46  -117 ?   ?   ?   R . n 
D 4 47  PRO 47  -116 ?   ?   ?   R . n 
D 4 48  ALA 48  -115 ?   ?   ?   R . n 
D 4 49  ASP 49  -114 ?   ?   ?   R . n 
D 4 50  LEU 50  -113 ?   ?   ?   R . n 
D 4 51  GLU 51  -112 ?   ?   ?   R . n 
D 4 52  ASP 52  -111 ?   ?   ?   R . n 
D 4 53  ASN 53  -110 ?   ?   ?   R . n 
D 4 54  TRP 54  -109 ?   ?   ?   R . n 
D 4 55  GLU 55  -108 ?   ?   ?   R . n 
D 4 56  THR 56  -107 ?   ?   ?   R . n 
D 4 57  LEU 57  -106 ?   ?   ?   R . n 
D 4 58  ASN 58  -105 ?   ?   ?   R . n 
D 4 59  ASP 59  -104 ?   ?   ?   R . n 
D 4 60  ASN 60  -103 ?   ?   ?   R . n 
D 4 61  LEU 61  -102 ?   ?   ?   R . n 
D 4 62  LYS 62  -101 ?   ?   ?   R . n 
D 4 63  VAL 63  -100 ?   ?   ?   R . n 
D 4 64  ILE 64  -99  ?   ?   ?   R . n 
D 4 65  GLU 65  -98  ?   ?   ?   R . n 
D 4 66  LYS 66  -97  ?   ?   ?   R . n 
D 4 67  ALA 67  -96  ?   ?   ?   R . n 
D 4 68  ASP 68  -95  ?   ?   ?   R . n 
D 4 69  ASN 69  -94  ?   ?   ?   R . n 
D 4 70  ALA 70  -93  ?   ?   ?   R . n 
D 4 71  ALA 71  -92  ?   ?   ?   R . n 
D 4 72  GLN 72  -91  ?   ?   ?   R . n 
D 4 73  VAL 73  -90  ?   ?   ?   R . n 
D 4 74  LYS 74  -89  ?   ?   ?   R . n 
D 4 75  ASP 75  -88  ?   ?   ?   R . n 
D 4 76  ALA 76  -87  ?   ?   ?   R . n 
D 4 77  LEU 77  -86  ?   ?   ?   R . n 
D 4 78  THR 78  -85  ?   ?   ?   R . n 
D 4 79  LYS 79  -84  ?   ?   ?   R . n 
D 4 80  MET 80  -83  ?   ?   ?   R . n 
D 4 81  ARG 81  -82  ?   ?   ?   R . n 
D 4 82  ALA 82  -81  ?   ?   ?   R . n 
D 4 83  ALA 83  -80  ?   ?   ?   R . n 
D 4 84  ALA 84  -79  ?   ?   ?   R . n 
D 4 85  LEU 85  -78  ?   ?   ?   R . n 
D 4 86  ASP 86  -77  ?   ?   ?   R . n 
D 4 87  ALA 87  -76  ?   ?   ?   R . n 
D 4 88  GLN 88  -75  ?   ?   ?   R . n 
D 4 89  LYS 89  -74  ?   ?   ?   R . n 
D 4 90  ALA 90  -73  ?   ?   ?   R . n 
D 4 91  THR 91  -72  ?   ?   ?   R . n 
D 4 92  PRO 92  -71  ?   ?   ?   R . n 
D 4 93  PRO 93  -70  ?   ?   ?   R . n 
D 4 94  LYS 94  -69  ?   ?   ?   R . n 
D 4 95  LEU 95  -68  ?   ?   ?   R . n 
D 4 96  GLU 96  -67  ?   ?   ?   R . n 
D 4 97  ASP 97  -66  ?   ?   ?   R . n 
D 4 98  LYS 98  -65  ?   ?   ?   R . n 
D 4 99  SER 99  -64  ?   ?   ?   R . n 
D 4 100 PRO 100 -63  ?   ?   ?   R . n 
D 4 101 ASP 101 -62  ?   ?   ?   R . n 
D 4 102 SER 102 -61  ?   ?   ?   R . n 
D 4 103 PRO 103 -60  ?   ?   ?   R . n 
D 4 104 GLU 104 -59  ?   ?   ?   R . n 
D 4 105 MET 105 -58  ?   ?   ?   R . n 
D 4 106 LYS 106 -57  ?   ?   ?   R . n 
D 4 107 ASP 107 -56  ?   ?   ?   R . n 
D 4 108 PHE 108 -55  ?   ?   ?   R . n 
D 4 109 ARG 109 -54  ?   ?   ?   R . n 
D 4 110 HIS 110 -53  ?   ?   ?   R . n 
D 4 111 GLY 111 -52  ?   ?   ?   R . n 
D 4 112 PHE 112 -51  ?   ?   ?   R . n 
D 4 113 ASP 113 -50  ?   ?   ?   R . n 
D 4 114 ILE 114 -49  ?   ?   ?   R . n 
D 4 115 LEU 115 -48  ?   ?   ?   R . n 
D 4 116 VAL 116 -47  ?   ?   ?   R . n 
D 4 117 GLY 117 -46  ?   ?   ?   R . n 
D 4 118 GLN 118 -45  ?   ?   ?   R . n 
D 4 119 ILE 119 -44  ?   ?   ?   R . n 
D 4 120 ASP 120 -43  ?   ?   ?   R . n 
D 4 121 ASP 121 -42  ?   ?   ?   R . n 
D 4 122 ALA 122 -41  ?   ?   ?   R . n 
D 4 123 LEU 123 -40  ?   ?   ?   R . n 
D 4 124 LYS 124 -39  ?   ?   ?   R . n 
D 4 125 LEU 125 -38  ?   ?   ?   R . n 
D 4 126 ALA 126 -37  ?   ?   ?   R . n 
D 4 127 ASN 127 -36  ?   ?   ?   R . n 
D 4 128 GLU 128 -35  ?   ?   ?   R . n 
D 4 129 GLY 129 -34  ?   ?   ?   R . n 
D 4 130 LYS 130 -33  ?   ?   ?   R . n 
D 4 131 VAL 131 -32  ?   ?   ?   R . n 
D 4 132 LYS 132 -31  ?   ?   ?   R . n 
D 4 133 GLU 133 -30  ?   ?   ?   R . n 
D 4 134 ALA 134 -29  ?   ?   ?   R . n 
D 4 135 GLN 135 -28  ?   ?   ?   R . n 
D 4 136 ALA 136 -27  ?   ?   ?   R . n 
D 4 137 ALA 137 -26  ?   ?   ?   R . n 
D 4 138 ALA 138 -25  ?   ?   ?   R . n 
D 4 139 GLU 139 -24  ?   ?   ?   R . n 
D 4 140 GLN 140 -23  ?   ?   ?   R . n 
D 4 141 LEU 141 -22  ?   ?   ?   R . n 
D 4 142 LYS 142 -21  ?   ?   ?   R . n 
D 4 143 THR 143 -20  ?   ?   ?   R . n 
D 4 144 THR 144 -19  ?   ?   ?   R . n 
D 4 145 ARG 145 -18  ?   ?   ?   R . n 
D 4 146 ASN 146 -17  ?   ?   ?   R . n 
D 4 147 ALA 147 -16  ?   ?   ?   R . n 
D 4 148 TYR 148 -15  ?   ?   ?   R . n 
D 4 149 ILE 149 -14  ?   ?   ?   R . n 
D 4 150 GLN 150 -13  ?   ?   ?   R . n 
D 4 151 LYS 151 -12  ?   ?   ?   R . n 
D 4 152 TYR 152 -11  ?   ?   ?   R . n 
D 4 153 LEU 153 -10  ?   ?   ?   R . n 
D 4 154 GLU 154 -9   ?   ?   ?   R . n 
D 4 155 PHE 155 -8   ?   ?   ?   R . n 
D 4 156 LEU 156 -7   ?   ?   ?   R . n 
D 4 157 GLU 157 -6   ?   ?   ?   R . n 
D 4 158 VAL 158 -5   ?   ?   ?   R . n 
D 4 159 LEU 159 -4   ?   ?   ?   R . n 
D 4 160 PHE 160 -3   ?   ?   ?   R . n 
D 4 161 GLN 161 -2   ?   ?   ?   R . n 
D 4 162 GLY 162 -1   ?   ?   ?   R . n 
D 4 163 PRO 163 0    ?   ?   ?   R . n 
D 4 164 ALA 164 1    ?   ?   ?   R . n 
D 4 165 ILE 165 2    ?   ?   ?   R . n 
D 4 166 ASN 166 3    ?   ?   ?   R . n 
D 4 167 SER 167 4    ?   ?   ?   R . n 
D 4 168 THR 168 5    ?   ?   ?   R . n 
D 4 169 SER 169 6    ?   ?   ?   R . n 
D 4 170 THR 170 7    ?   ?   ?   R . n 
D 4 171 GLN 171 8    ?   ?   ?   R . n 
D 4 172 PRO 172 9    ?   ?   ?   R . n 
D 4 173 PRO 173 10   ?   ?   ?   R . n 
D 4 174 ASP 174 11   ?   ?   ?   R . n 
D 4 175 GLU 175 12   ?   ?   ?   R . n 
D 4 176 SER 176 13   ?   ?   ?   R . n 
D 4 177 CYS 177 14   ?   ?   ?   R . n 
D 4 178 SER 178 15   15  SER SER R . n 
D 4 179 GLN 179 16   16  GLN GLN R . n 
D 4 180 ASN 180 17   17  ASN ASN R . n 
D 4 181 LEU 181 18   18  LEU LEU R . n 
D 4 182 LEU 182 19   19  LEU LEU R . n 
D 4 183 ILE 183 20   20  ILE ILE R . n 
D 4 184 THR 184 21   21  THR THR R . n 
D 4 185 GLN 185 22   22  GLN GLN R . n 
D 4 186 GLN 186 23   23  GLN GLN R . n 
D 4 187 ILE 187 24   24  ILE ILE R . n 
D 4 188 ILE 188 25   25  ILE ILE R . n 
D 4 189 PRO 189 26   26  PRO PRO R . n 
D 4 190 VAL 190 27   27  VAL VAL R . n 
D 4 191 LEU 191 28   28  LEU LEU R . n 
D 4 192 TYR 192 29   29  TYR TYR R . n 
D 4 193 CYS 193 30   30  CYS CYS R . n 
D 4 194 MET 194 31   31  MET MET R . n 
D 4 195 VAL 195 32   32  VAL VAL R . n 
D 4 196 PHE 196 33   33  PHE PHE R . n 
D 4 197 ILE 197 34   34  ILE ILE R . n 
D 4 198 ALA 198 35   35  ALA ALA R . n 
D 4 199 GLY 199 36   36  GLY GLY R . n 
D 4 200 ILE 200 37   37  ILE ILE R . n 
D 4 201 LEU 201 38   38  LEU LEU R . n 
D 4 202 LEU 202 39   39  LEU LEU R . n 
D 4 203 ASN 203 40   40  ASN ASN R . n 
D 4 204 GLY 204 41   41  GLY GLY R . n 
D 4 205 VAL 205 42   42  VAL VAL R . n 
D 4 206 SER 206 43   43  SER SER R . n 
D 4 207 GLY 207 44   44  GLY GLY R . n 
D 4 208 TRP 208 45   45  TRP TRP R . n 
D 4 209 ILE 209 46   46  ILE ILE R . n 
D 4 210 PHE 210 47   47  PHE PHE R . n 
D 4 211 PHE 211 48   48  PHE PHE R . n 
D 4 212 TYR 212 49   49  TYR TYR R . n 
D 4 213 VAL 213 50   50  VAL VAL R . n 
D 4 214 PRO 214 51   51  PRO PRO R . n 
D 4 215 SER 215 52   52  SER SER R . n 
D 4 216 SER 216 53   53  SER SER R . n 
D 4 217 LYS 217 54   54  LYS LYS R . n 
D 4 218 SER 218 55   55  SER SER R . n 
D 4 219 PHE 219 56   56  PHE PHE R . n 
D 4 220 ILE 220 57   57  ILE ILE R . n 
D 4 221 ILE 221 58   58  ILE ILE R . n 
D 4 222 TYR 222 59   59  TYR TYR R . n 
D 4 223 LEU 223 60   60  LEU LEU R . n 
D 4 224 LYS 224 61   61  LYS LYS R . n 
D 4 225 ASN 225 62   62  ASN ASN R . n 
D 4 226 ILE 226 63   63  ILE ILE R . n 
D 4 227 VAL 227 64   64  VAL VAL R . n 
D 4 228 ILE 228 65   65  ILE ILE R . n 
D 4 229 ALA 229 66   66  ALA ALA R . n 
D 4 230 ASP 230 67   67  ASP ASP R . n 
D 4 231 PHE 231 68   68  PHE PHE R . n 
D 4 232 VAL 232 69   69  VAL VAL R . n 
D 4 233 MET 233 70   70  MET MET R . n 
D 4 234 SER 234 71   71  SER SER R . n 
D 4 235 LEU 235 72   72  LEU LEU R . n 
D 4 236 THR 236 73   73  THR THR R . n 
D 4 237 PHE 237 74   74  PHE PHE R . n 
D 4 238 PRO 238 75   75  PRO PRO R . n 
D 4 239 PHE 239 76   76  PHE PHE R . n 
D 4 240 LYS 240 77   77  LYS LYS R . n 
D 4 241 ILE 241 78   78  ILE ILE R . n 
D 4 242 LEU 242 79   79  LEU LEU R . n 
D 4 243 GLY 243 80   80  GLY GLY R . n 
D 4 244 ASP 244 81   81  ASP ASP R . n 
D 4 245 SER 245 82   82  SER SER R . n 
D 4 246 GLY 246 83   83  GLY GLY R . n 
D 4 247 LEU 247 84   84  LEU LEU R . n 
D 4 248 GLY 248 85   85  GLY GLY R . n 
D 4 249 PRO 249 86   86  PRO PRO R . n 
D 4 250 TRP 250 87   87  TRP TRP R . n 
D 4 251 GLN 251 88   88  GLN GLN R . n 
D 4 252 LEU 252 89   89  LEU LEU R . n 
D 4 253 ASN 253 90   90  ASN ASN R . n 
D 4 254 VAL 254 91   91  VAL VAL R . n 
D 4 255 PHE 255 92   92  PHE PHE R . n 
D 4 256 VAL 256 93   93  VAL VAL R . n 
D 4 257 CYS 257 94   94  CYS CYS R . n 
D 4 258 ARG 258 95   95  ARG ARG R . n 
D 4 259 VAL 259 96   96  VAL VAL R . n 
D 4 260 SER 260 97   97  SER SER R . n 
D 4 261 ALA 261 98   98  ALA ALA R . n 
D 4 262 VAL 262 99   99  VAL VAL R . n 
D 4 263 LEU 263 100  100 LEU LEU R . n 
D 4 264 PHE 264 101  101 PHE PHE R . n 
D 4 265 TYR 265 102  102 TYR TYR R . n 
D 4 266 VAL 266 103  103 VAL VAL R . n 
D 4 267 ASN 267 104  104 ASN ASN R . n 
D 4 268 MET 268 105  105 MET MET R . n 
D 4 269 TYR 269 106  106 TYR TYR R . n 
D 4 270 VAL 270 107  107 VAL VAL R . n 
D 4 271 SER 271 108  108 SER SER R . n 
D 4 272 ILE 272 109  109 ILE ILE R . n 
D 4 273 VAL 273 110  110 VAL VAL R . n 
D 4 274 PHE 274 111  111 PHE PHE R . n 
D 4 275 PHE 275 112  112 PHE PHE R . n 
D 4 276 GLY 276 113  113 GLY GLY R . n 
D 4 277 LEU 277 114  114 LEU LEU R . n 
D 4 278 ILE 278 115  115 ILE ILE R . n 
D 4 279 SER 279 116  116 SER SER R . n 
D 4 280 PHE 280 117  117 PHE PHE R . n 
D 4 281 ASP 281 118  118 ASP ASP R . n 
D 4 282 ARG 282 119  119 ARG ARG R . n 
D 4 283 TYR 283 120  120 TYR TYR R . n 
D 4 284 TYR 284 121  121 TYR TYR R . n 
D 4 285 LYS 285 122  122 LYS LYS R . n 
D 4 286 ILE 286 123  123 ILE ILE R . n 
D 4 287 VAL 287 124  124 VAL VAL R . n 
D 4 288 LYS 288 125  125 LYS LYS R . n 
D 4 289 PRO 289 126  126 PRO PRO R . n 
D 4 290 LEU 290 127  127 LEU LEU R . n 
D 4 291 TRP 291 128  128 TRP TRP R . n 
D 4 292 THR 292 129  129 THR THR R . n 
D 4 293 SER 293 130  130 SER SER R . n 
D 4 294 PHE 294 131  131 PHE PHE R . n 
D 4 295 ILE 295 132  132 ILE ILE R . n 
D 4 296 GLN 296 133  133 GLN GLN R . n 
D 4 297 SER 297 134  134 SER SER R . n 
D 4 298 VAL 298 135  135 VAL VAL R . n 
D 4 299 SER 299 136  136 SER SER R . n 
D 4 300 TYR 300 137  137 TYR TYR R . n 
D 4 301 SER 301 138  138 SER SER R . n 
D 4 302 LYS 302 139  139 LYS LYS R . n 
D 4 303 LEU 303 140  140 LEU LEU R . n 
D 4 304 LEU 304 141  141 LEU LEU R . n 
D 4 305 SER 305 142  142 SER SER R . n 
D 4 306 VAL 306 143  143 VAL VAL R . n 
D 4 307 ILE 307 144  144 ILE ILE R . n 
D 4 308 VAL 308 145  145 VAL VAL R . n 
D 4 309 TRP 309 146  146 TRP TRP R . n 
D 4 310 MET 310 147  147 MET MET R . n 
D 4 311 LEU 311 148  148 LEU LEU R . n 
D 4 312 MET 312 149  149 MET MET R . n 
D 4 313 LEU 313 150  150 LEU LEU R . n 
D 4 314 LEU 314 151  151 LEU LEU R . n 
D 4 315 LEU 315 152  152 LEU LEU R . n 
D 4 316 ALA 316 153  153 ALA ALA R . n 
D 4 317 VAL 317 154  154 VAL VAL R . n 
D 4 318 PRO 318 155  155 PRO PRO R . n 
D 4 319 ASN 319 156  156 ASN ASN R . n 
D 4 320 ILE 320 157  157 ILE ILE R . n 
D 4 321 ILE 321 158  158 ILE ILE R . n 
D 4 322 LEU 322 159  159 LEU LEU R . n 
D 4 323 THR 323 160  160 THR THR R . n 
D 4 324 ASN 324 161  161 ASN ASN R . n 
D 4 325 GLN 325 162  162 GLN GLN R . n 
D 4 326 SER 326 163  163 SER SER R . n 
D 4 327 VAL 327 164  164 VAL VAL R . n 
D 4 328 ARG 328 165  165 ARG ARG R . n 
D 4 329 GLU 329 166  166 GLU GLU R . n 
D 4 330 VAL 330 167  167 VAL VAL R . n 
D 4 331 THR 331 168  168 THR THR R . n 
D 4 332 GLN 332 169  169 GLN GLN R . n 
D 4 333 ILE 333 170  170 ILE ILE R . n 
D 4 334 LYS 334 171  171 LYS LYS R . n 
D 4 335 CYS 335 172  172 CYS CYS R . n 
D 4 336 ILE 336 173  173 ILE ILE R . n 
D 4 337 GLU 337 174  174 GLU GLU R . n 
D 4 338 LEU 338 175  175 LEU LEU R . n 
D 4 339 LYS 339 176  176 LYS LYS R . n 
D 4 340 SER 340 177  177 SER SER R . n 
D 4 341 GLU 341 178  178 GLU GLU R . n 
D 4 342 LEU 342 179  179 LEU LEU R . n 
D 4 343 GLY 343 180  180 GLY GLY R . n 
D 4 344 ARG 344 181  181 ARG ARG R . n 
D 4 345 LYS 345 182  182 LYS LYS R . n 
D 4 346 TRP 346 183  183 TRP TRP R . n 
D 4 347 HIS 347 184  184 HIS HIS R . n 
D 4 348 LYS 348 185  185 LYS LYS R . n 
D 4 349 ALA 349 186  186 ALA ALA R . n 
D 4 350 SER 350 187  187 SER SER R . n 
D 4 351 ASN 351 188  188 ASN ASN R . n 
D 4 352 TYR 352 189  189 TYR TYR R . n 
D 4 353 ILE 353 190  190 ILE ILE R . n 
D 4 354 PHE 354 191  191 PHE PHE R . n 
D 4 355 VAL 355 192  192 VAL VAL R . n 
D 4 356 ALA 356 193  193 ALA ALA R . n 
D 4 357 ILE 357 194  194 ILE ILE R . n 
D 4 358 PHE 358 195  195 PHE PHE R . n 
D 4 359 TRP 359 196  196 TRP TRP R . n 
D 4 360 ILE 360 197  197 ILE ILE R . n 
D 4 361 VAL 361 198  198 VAL VAL R . n 
D 4 362 PHE 362 199  199 PHE PHE R . n 
D 4 363 LEU 363 200  200 LEU LEU R . n 
D 4 364 LEU 364 201  201 LEU LEU R . n 
D 4 365 LEU 365 202  202 LEU LEU R . n 
D 4 366 ILE 366 203  203 ILE ILE R . n 
D 4 367 VAL 367 204  204 VAL VAL R . n 
D 4 368 PHE 368 205  205 PHE PHE R . n 
D 4 369 TYR 369 206  206 TYR TYR R . n 
D 4 370 THR 370 207  207 THR THR R . n 
D 4 371 ALA 371 208  208 ALA ALA R . n 
D 4 372 ILE 372 209  209 ILE ILE R . n 
D 4 373 THR 373 210  210 THR THR R . n 
D 4 374 LYS 374 211  211 LYS LYS R . n 
D 4 375 LYS 375 212  212 LYS LYS R . n 
D 4 376 ILE 376 213  213 ILE ILE R . n 
D 4 377 PHE 377 214  214 PHE PHE R . n 
D 4 378 LYS 378 215  215 LYS LYS R . n 
D 4 379 SER 379 216  216 SER SER R . n 
D 4 380 HIS 380 217  217 HIS HIS R . n 
D 4 381 LEU 381 218  218 LEU LEU R . n 
D 4 382 LYS 382 219  219 LYS LYS R . n 
D 4 383 SER 383 220  220 SER SER R . n 
D 4 384 SER 384 221  221 SER SER R . n 
D 4 385 ARG 385 222  222 ARG ARG R . n 
D 4 386 ASN 386 223  223 ASN ASN R . n 
D 4 387 SER 387 224  224 SER SER R . n 
D 4 388 THR 388 225  225 THR THR R . n 
D 4 389 SER 389 226  226 SER SER R . n 
D 4 390 VAL 390 227  227 VAL VAL R . n 
D 4 391 LYS 391 228  228 LYS LYS R . n 
D 4 392 LYS 392 229  229 LYS LYS R . n 
D 4 393 LYS 393 230  230 LYS LYS R . n 
D 4 394 SER 394 231  231 SER SER R . n 
D 4 395 SER 395 232  232 SER SER R . n 
D 4 396 ARG 396 233  233 ARG ARG R . n 
D 4 397 ASN 397 234  234 ASN ASN R . n 
D 4 398 ILE 398 235  235 ILE ILE R . n 
D 4 399 PHE 399 236  236 PHE PHE R . n 
D 4 400 SER 400 237  237 SER SER R . n 
D 4 401 ILE 401 238  238 ILE ILE R . n 
D 4 402 VAL 402 239  239 VAL VAL R . n 
D 4 403 PHE 403 240  240 PHE PHE R . n 
D 4 404 VAL 404 241  241 VAL VAL R . n 
D 4 405 PHE 405 242  242 PHE PHE R . n 
D 4 406 PHE 406 243  243 PHE PHE R . n 
D 4 407 VAL 407 244  244 VAL VAL R . n 
D 4 408 CYS 408 245  245 CYS CYS R . n 
D 4 409 PHE 409 246  246 PHE PHE R . n 
D 4 410 VAL 410 247  247 VAL VAL R . n 
D 4 411 PRO 411 248  248 PRO PRO R . n 
D 4 412 TYR 412 249  249 TYR TYR R . n 
D 4 413 HIS 413 250  250 HIS HIS R . n 
D 4 414 ILE 414 251  251 ILE ILE R . n 
D 4 415 ALA 415 252  252 ALA ALA R . n 
D 4 416 ARG 416 253  253 ARG ARG R . n 
D 4 417 ILE 417 254  254 ILE ILE R . n 
D 4 418 PRO 418 255  255 PRO PRO R . n 
D 4 419 TYR 419 256  256 TYR TYR R . n 
D 4 420 THR 420 257  257 THR THR R . n 
D 4 421 LYS 421 258  258 LYS LYS R . n 
D 4 422 SER 422 259  259 SER SER R . n 
D 4 423 GLN 423 260  260 GLN GLN R . n 
D 4 424 THR 424 261  261 THR THR R . n 
D 4 425 GLU 425 262  262 GLU GLU R . n 
D 4 426 ALA 426 263  263 ALA ALA R . n 
D 4 427 HIS 427 264  264 HIS HIS R . n 
D 4 428 TYR 428 265  265 TYR TYR R . n 
D 4 429 SER 429 266  266 SER SER R . n 
D 4 430 CYS 430 267  267 CYS CYS R . n 
D 4 431 GLN 431 268  268 GLN GLN R . n 
D 4 432 SER 432 269  269 SER SER R . n 
D 4 433 LYS 433 270  270 LYS LYS R . n 
D 4 434 GLU 434 271  271 GLU GLU R . n 
D 4 435 ILE 435 272  272 ILE ILE R . n 
D 4 436 LEU 436 273  273 LEU LEU R . n 
D 4 437 ARG 437 274  274 ARG ARG R . n 
D 4 438 TYR 438 275  275 TYR TYR R . n 
D 4 439 MET 439 276  276 MET MET R . n 
D 4 440 LYS 440 277  277 LYS LYS R . n 
D 4 441 GLU 441 278  278 GLU GLU R . n 
D 4 442 PHE 442 279  279 PHE PHE R . n 
D 4 443 THR 443 280  280 THR THR R . n 
D 4 444 LEU 444 281  281 LEU LEU R . n 
D 4 445 LEU 445 282  282 LEU LEU R . n 
D 4 446 LEU 446 283  283 LEU LEU R . n 
D 4 447 SER 447 284  284 SER SER R . n 
D 4 448 ALA 448 285  285 ALA ALA R . n 
D 4 449 ALA 449 286  286 ALA ALA R . n 
D 4 450 ASN 450 287  287 ASN ASN R . n 
D 4 451 VAL 451 288  288 VAL VAL R . n 
D 4 452 CYS 452 289  289 CYS CYS R . n 
D 4 453 LEU 453 290  290 LEU LEU R . n 
D 4 454 ASP 454 291  291 ASP ASP R . n 
D 4 455 PRO 455 292  292 PRO PRO R . n 
D 4 456 ILE 456 293  293 ILE ILE R . n 
D 4 457 ILE 457 294  294 ILE ILE R . n 
D 4 458 TYR 458 295  295 TYR TYR R . n 
D 4 459 PHE 459 296  296 PHE PHE R . n 
D 4 460 PHE 460 297  297 PHE PHE R . n 
D 4 461 LEU 461 298  298 LEU LEU R . n 
D 4 462 CYS 462 299  299 CYS CYS R . n 
D 4 463 GLN 463 300  300 GLN GLN R . n 
D 4 464 PRO 464 301  301 PRO PRO R . n 
D 4 465 PHE 465 302  302 PHE PHE R . n 
D 4 466 ARG 466 303  303 ARG ARG R . n 
D 4 467 GLU 467 304  304 GLU GLU R . n 
D 4 468 ILE 468 305  305 ILE ILE R . n 
D 4 469 LEU 469 306  306 LEU LEU R . n 
D 4 470 CYS 470 307  307 CYS CYS R . n 
D 4 471 LYS 471 308  308 LYS LYS R . n 
D 4 472 LYS 472 309  309 LYS LYS R . n 
D 4 473 LEU 473 310  310 LEU LEU R . n 
D 4 474 HIS 474 311  311 HIS HIS R . n 
D 4 475 ILE 475 312  ?   ?   ?   R . n 
D 4 476 PRO 476 313  ?   ?   ?   R . n 
D 4 477 LEU 477 314  ?   ?   ?   R . n 
D 4 478 LYS 478 315  ?   ?   ?   R . n 
D 4 479 ALA 479 316  ?   ?   ?   R . n 
D 4 480 GLN 480 317  ?   ?   ?   R . n 
D 4 481 ASN 481 318  ?   ?   ?   R . n 
D 4 482 ASP 482 319  ?   ?   ?   R . n 
D 4 483 LEU 483 320  ?   ?   ?   R . n 
D 4 484 ASP 484 321  ?   ?   ?   R . n 
D 4 485 ILE 485 322  ?   ?   ?   R . n 
D 4 486 SER 486 323  ?   ?   ?   R . n 
D 4 487 ARG 487 324  ?   ?   ?   R . n 
D 4 488 ILE 488 325  ?   ?   ?   R . n 
D 4 489 LYS 489 326  ?   ?   ?   R . n 
D 4 490 ARG 490 327  ?   ?   ?   R . n 
D 4 491 GLY 491 328  ?   ?   ?   R . n 
D 4 492 ASN 492 329  ?   ?   ?   R . n 
D 4 493 THR 493 330  ?   ?   ?   R . n 
D 4 494 THR 494 331  ?   ?   ?   R . n 
D 4 495 LEU 495 332  ?   ?   ?   R . n 
D 4 496 GLU 496 333  ?   ?   ?   R . n 
D 4 497 SER 497 334  ?   ?   ?   R . n 
D 4 498 THR 498 335  ?   ?   ?   R . n 
D 4 499 ASP 499 336  ?   ?   ?   R . n 
D 4 500 THR 500 337  ?   ?   ?   R . n 
D 4 501 LEU 501 338  ?   ?   ?   R . n 
E 5 1   MET 1   -37  ?   ?   ?   S . n 
E 5 2   LEU 2   -36  ?   ?   ?   S . n 
E 5 3   LEU 3   -35  ?   ?   ?   S . n 
E 5 4   VAL 4   -34  ?   ?   ?   S . n 
E 5 5   ASN 5   -33  ?   ?   ?   S . n 
E 5 6   GLN 6   -32  ?   ?   ?   S . n 
E 5 7   SER 7   -31  ?   ?   ?   S . n 
E 5 8   HIS 8   -30  ?   ?   ?   S . n 
E 5 9   GLN 9   -29  ?   ?   ?   S . n 
E 5 10  GLY 10  -28  ?   ?   ?   S . n 
E 5 11  PHE 11  -27  ?   ?   ?   S . n 
E 5 12  ASN 12  -26  ?   ?   ?   S . n 
E 5 13  LYS 13  -25  ?   ?   ?   S . n 
E 5 14  GLU 14  -24  ?   ?   ?   S . n 
E 5 15  HIS 15  -23  ?   ?   ?   S . n 
E 5 16  THR 16  -22  ?   ?   ?   S . n 
E 5 17  SER 17  -21  ?   ?   ?   S . n 
E 5 18  LYS 18  -20  ?   ?   ?   S . n 
E 5 19  MET 19  -19  ?   ?   ?   S . n 
E 5 20  VAL 20  -18  ?   ?   ?   S . n 
E 5 21  SER 21  -17  ?   ?   ?   S . n 
E 5 22  ALA 22  -16  ?   ?   ?   S . n 
E 5 23  ILE 23  -15  ?   ?   ?   S . n 
E 5 24  VAL 24  -14  ?   ?   ?   S . n 
E 5 25  LEU 25  -13  ?   ?   ?   S . n 
E 5 26  TYR 26  -12  ?   ?   ?   S . n 
E 5 27  VAL 27  -11  ?   ?   ?   S . n 
E 5 28  LEU 28  -10  ?   ?   ?   S . n 
E 5 29  LEU 29  -9   ?   ?   ?   S . n 
E 5 30  ALA 30  -8   ?   ?   ?   S . n 
E 5 31  ALA 31  -7   ?   ?   ?   S . n 
E 5 32  ALA 32  -6   ?   ?   ?   S . n 
E 5 33  ALA 33  -5   ?   ?   ?   S . n 
E 5 34  HIS 34  -4   ?   ?   ?   S . n 
E 5 35  SER 35  -3   ?   ?   ?   S . n 
E 5 36  ALA 36  -2   ?   ?   ?   S . n 
E 5 37  PHE 37  -1   ?   ?   ?   S . n 
E 5 38  ALA 38  0    ?   ?   ?   S . n 
E 5 39  ASP 39  1    1   ASP ASP S . n 
E 5 40  VAL 40  2    2   VAL VAL S . n 
E 5 41  GLN 41  3    3   GLN GLN S . n 
E 5 42  LEU 42  4    4   LEU LEU S . n 
E 5 43  VAL 43  5    5   VAL VAL S . n 
E 5 44  GLU 44  6    6   GLU GLU S . n 
E 5 45  SER 45  7    7   SER SER S . n 
E 5 46  GLY 46  8    8   GLY GLY S . n 
E 5 47  GLY 47  9    9   GLY GLY S . n 
E 5 48  GLY 48  10   10  GLY GLY S . n 
E 5 49  LEU 49  11   11  LEU LEU S . n 
E 5 50  VAL 50  12   12  VAL VAL S . n 
E 5 51  GLN 51  13   13  GLN GLN S . n 
E 5 52  PRO 52  14   14  PRO PRO S . n 
E 5 53  GLY 53  15   15  GLY GLY S . n 
E 5 54  GLY 54  16   16  GLY GLY S . n 
E 5 55  SER 55  17   17  SER SER S . n 
E 5 56  ARG 56  18   18  ARG ARG S . n 
E 5 57  LYS 57  19   19  LYS LYS S . n 
E 5 58  LEU 58  20   20  LEU LEU S . n 
E 5 59  SER 59  21   21  SER SER S . n 
E 5 60  CYS 60  22   22  CYS CYS S . n 
E 5 61  SER 61  23   23  SER SER S . n 
E 5 62  ALA 62  24   24  ALA ALA S . n 
E 5 63  SER 63  25   25  SER SER S . n 
E 5 64  GLY 64  26   26  GLY GLY S . n 
E 5 65  PHE 65  27   27  PHE PHE S . n 
E 5 66  ALA 66  28   28  ALA ALA S . n 
E 5 67  PHE 67  29   29  PHE PHE S . n 
E 5 68  SER 68  30   30  SER SER S . n 
E 5 69  SER 69  31   31  SER SER S . n 
E 5 70  PHE 70  32   32  PHE PHE S . n 
E 5 71  GLY 71  33   33  GLY GLY S . n 
E 5 72  MET 72  34   34  MET MET S . n 
E 5 73  HIS 73  35   35  HIS HIS S . n 
E 5 74  TRP 74  36   36  TRP TRP S . n 
E 5 75  VAL 75  37   37  VAL VAL S . n 
E 5 76  ARG 76  38   38  ARG ARG S . n 
E 5 77  GLN 77  39   39  GLN GLN S . n 
E 5 78  ALA 78  40   40  ALA ALA S . n 
E 5 79  PRO 79  41   41  PRO PRO S . n 
E 5 80  GLU 80  42   42  GLU GLU S . n 
E 5 81  LYS 81  43   43  LYS LYS S . n 
E 5 82  GLY 82  44   44  GLY GLY S . n 
E 5 83  LEU 83  45   45  LEU LEU S . n 
E 5 84  GLU 84  46   46  GLU GLU S . n 
E 5 85  TRP 85  47   47  TRP TRP S . n 
E 5 86  VAL 86  48   48  VAL VAL S . n 
E 5 87  ALA 87  49   49  ALA ALA S . n 
E 5 88  TYR 88  50   50  TYR TYR S . n 
E 5 89  ILE 89  51   51  ILE ILE S . n 
E 5 90  SER 90  52   52  SER SER S . n 
E 5 91  SER 91  53   53  SER SER S . n 
E 5 92  GLY 92  54   54  GLY GLY S . n 
E 5 93  SER 93  55   55  SER SER S . n 
E 5 94  GLY 94  56   56  GLY GLY S . n 
E 5 95  THR 95  57   57  THR THR S . n 
E 5 96  ILE 96  58   58  ILE ILE S . n 
E 5 97  TYR 97  59   59  TYR TYR S . n 
E 5 98  TYR 98  60   60  TYR TYR S . n 
E 5 99  ALA 99  61   61  ALA ALA S . n 
E 5 100 ASP 100 62   62  ASP ASP S . n 
E 5 101 THR 101 63   63  THR THR S . n 
E 5 102 VAL 102 64   64  VAL VAL S . n 
E 5 103 LYS 103 65   65  LYS LYS S . n 
E 5 104 GLY 104 66   66  GLY GLY S . n 
E 5 105 ARG 105 67   67  ARG ARG S . n 
E 5 106 PHE 106 68   68  PHE PHE S . n 
E 5 107 THR 107 69   69  THR THR S . n 
E 5 108 ILE 108 70   70  ILE ILE S . n 
E 5 109 SER 109 71   71  SER SER S . n 
E 5 110 ARG 110 72   72  ARG ARG S . n 
E 5 111 ASP 111 73   73  ASP ASP S . n 
E 5 112 ASP 112 74   74  ASP ASP S . n 
E 5 113 PRO 113 75   75  PRO PRO S . n 
E 5 114 LYS 114 76   76  LYS LYS S . n 
E 5 115 ASN 115 77   77  ASN ASN S . n 
E 5 116 THR 116 78   78  THR THR S . n 
E 5 117 LEU 117 79   79  LEU LEU S . n 
E 5 118 PHE 118 80   80  PHE PHE S . n 
E 5 119 LEU 119 81   81  LEU LEU S . n 
E 5 120 GLN 120 82   82  GLN GLN S . n 
E 5 121 MET 121 83   83  MET MET S . n 
E 5 122 THR 122 84   84  THR THR S . n 
E 5 123 SER 123 85   85  SER SER S . n 
E 5 124 LEU 124 86   86  LEU LEU S . n 
E 5 125 ARG 125 87   87  ARG ARG S . n 
E 5 126 SER 126 88   88  SER SER S . n 
E 5 127 GLU 127 89   89  GLU GLU S . n 
E 5 128 ASP 128 90   90  ASP ASP S . n 
E 5 129 THR 129 91   91  THR THR S . n 
E 5 130 ALA 130 92   92  ALA ALA S . n 
E 5 131 MET 131 93   93  MET MET S . n 
E 5 132 TYR 132 94   94  TYR TYR S . n 
E 5 133 TYR 133 95   95  TYR TYR S . n 
E 5 134 CYS 134 96   96  CYS CYS S . n 
E 5 135 VAL 135 97   97  VAL VAL S . n 
E 5 136 ARG 136 98   98  ARG ARG S . n 
E 5 137 SER 137 99   99  SER SER S . n 
E 5 138 ILE 138 100  100 ILE ILE S . n 
E 5 139 TYR 139 101  101 TYR TYR S . n 
E 5 140 TYR 140 102  102 TYR TYR S . n 
E 5 141 TYR 141 103  103 TYR TYR S . n 
E 5 142 GLY 142 104  104 GLY GLY S . n 
E 5 143 SER 143 105  105 SER SER S . n 
E 5 144 SER 144 106  106 SER SER S . n 
E 5 145 PRO 145 107  107 PRO PRO S . n 
E 5 146 PHE 146 108  108 PHE PHE S . n 
E 5 147 ASP 147 109  109 ASP ASP S . n 
E 5 148 PHE 148 110  110 PHE PHE S . n 
E 5 149 TRP 149 111  111 TRP TRP S . n 
E 5 150 GLY 150 112  112 GLY GLY S . n 
E 5 151 GLN 151 113  113 GLN GLN S . n 
E 5 152 GLY 152 114  114 GLY GLY S . n 
E 5 153 THR 153 115  115 THR THR S . n 
E 5 154 THR 154 116  116 THR THR S . n 
E 5 155 LEU 155 117  117 LEU LEU S . n 
E 5 156 THR 156 118  118 THR THR S . n 
E 5 157 VAL 157 119  119 VAL VAL S . n 
E 5 158 SER 158 120  120 SER SER S . n 
E 5 159 SER 159 121  ?   ?   ?   S . n 
E 5 160 GLY 160 122  ?   ?   ?   S . n 
E 5 161 GLY 161 123  ?   ?   ?   S . n 
E 5 162 GLY 162 124  ?   ?   ?   S . n 
E 5 163 GLY 163 125  ?   ?   ?   S . n 
E 5 164 SER 164 126  ?   ?   ?   S . n 
E 5 165 GLY 165 127  ?   ?   ?   S . n 
E 5 166 GLY 166 128  ?   ?   ?   S . n 
E 5 167 GLY 167 129  ?   ?   ?   S . n 
E 5 168 GLY 168 130  ?   ?   ?   S . n 
E 5 169 SER 169 131  ?   ?   ?   S . n 
E 5 170 GLY 170 132  ?   ?   ?   S . n 
E 5 171 GLY 171 133  ?   ?   ?   S . n 
E 5 172 GLY 172 134  ?   ?   ?   S . n 
E 5 173 GLY 173 135  135 GLY GLY S . n 
E 5 174 SER 174 136  136 SER SER S . n 
E 5 175 ASP 175 137  137 ASP ASP S . n 
E 5 176 ILE 176 138  138 ILE ILE S . n 
E 5 177 VAL 177 139  139 VAL VAL S . n 
E 5 178 MET 178 140  140 MET MET S . n 
E 5 179 THR 179 141  141 THR THR S . n 
E 5 180 GLN 180 142  142 GLN GLN S . n 
E 5 181 ALA 181 143  143 ALA ALA S . n 
E 5 182 THR 182 144  144 THR THR S . n 
E 5 183 SER 183 145  145 SER SER S . n 
E 5 184 SER 184 146  146 SER SER S . n 
E 5 185 VAL 185 147  147 VAL VAL S . n 
E 5 186 PRO 186 148  148 PRO PRO S . n 
E 5 187 VAL 187 149  149 VAL VAL S . n 
E 5 188 THR 188 150  150 THR THR S . n 
E 5 189 PRO 189 151  151 PRO PRO S . n 
E 5 190 GLY 190 152  152 GLY GLY S . n 
E 5 191 GLU 191 153  153 GLU GLU S . n 
E 5 192 SER 192 154  154 SER SER S . n 
E 5 193 VAL 193 155  155 VAL VAL S . n 
E 5 194 SER 194 156  156 SER SER S . n 
E 5 195 ILE 195 157  157 ILE ILE S . n 
E 5 196 SER 196 158  158 SER SER S . n 
E 5 197 CYS 197 159  159 CYS CYS S . n 
E 5 198 ARG 198 160  160 ARG ARG S . n 
E 5 199 SER 199 161  161 SER SER S . n 
E 5 200 SER 200 162  162 SER SER S . n 
E 5 201 LYS 201 163  163 LYS LYS S . n 
E 5 202 SER 202 164  164 SER SER S . n 
E 5 203 LEU 203 165  165 LEU LEU S . n 
E 5 204 LEU 204 166  166 LEU LEU S . n 
E 5 205 HIS 205 167  167 HIS HIS S . n 
E 5 206 SER 206 168  168 SER SER S . n 
E 5 207 ASN 207 169  169 ASN ASN S . n 
E 5 208 GLY 208 170  170 GLY GLY S . n 
E 5 209 ASN 209 171  171 ASN ASN S . n 
E 5 210 THR 210 172  172 THR THR S . n 
E 5 211 TYR 211 173  173 TYR TYR S . n 
E 5 212 LEU 212 174  174 LEU LEU S . n 
E 5 213 TYR 213 175  175 TYR TYR S . n 
E 5 214 TRP 214 176  176 TRP TRP S . n 
E 5 215 PHE 215 177  177 PHE PHE S . n 
E 5 216 LEU 216 178  178 LEU LEU S . n 
E 5 217 GLN 217 179  179 GLN GLN S . n 
E 5 218 ARG 218 180  180 ARG ARG S . n 
E 5 219 PRO 219 181  181 PRO PRO S . n 
E 5 220 GLY 220 182  182 GLY GLY S . n 
E 5 221 GLN 221 183  183 GLN GLN S . n 
E 5 222 SER 222 184  184 SER SER S . n 
E 5 223 PRO 223 185  185 PRO PRO S . n 
E 5 224 GLN 224 186  186 GLN GLN S . n 
E 5 225 LEU 225 187  187 LEU LEU S . n 
E 5 226 LEU 226 188  188 LEU LEU S . n 
E 5 227 ILE 227 189  189 ILE ILE S . n 
E 5 228 TYR 228 190  190 TYR TYR S . n 
E 5 229 ARG 229 191  191 ARG ARG S . n 
E 5 230 MET 230 192  192 MET MET S . n 
E 5 231 SER 231 193  193 SER SER S . n 
E 5 232 ASN 232 194  194 ASN ASN S . n 
E 5 233 LEU 233 195  195 LEU LEU S . n 
E 5 234 ALA 234 196  196 ALA ALA S . n 
E 5 235 SER 235 197  197 SER SER S . n 
E 5 236 GLY 236 198  198 GLY GLY S . n 
E 5 237 VAL 237 199  199 VAL VAL S . n 
E 5 238 PRO 238 200  200 PRO PRO S . n 
E 5 239 ASP 239 201  201 ASP ASP S . n 
E 5 240 ARG 240 202  202 ARG ARG S . n 
E 5 241 PHE 241 203  203 PHE PHE S . n 
E 5 242 SER 242 204  204 SER SER S . n 
E 5 243 GLY 243 205  205 GLY GLY S . n 
E 5 244 SER 244 206  206 SER SER S . n 
E 5 245 GLY 245 207  207 GLY GLY S . n 
E 5 246 SER 246 208  208 SER SER S . n 
E 5 247 GLY 247 209  209 GLY GLY S . n 
E 5 248 THR 248 210  210 THR THR S . n 
E 5 249 ALA 249 211  211 ALA ALA S . n 
E 5 250 PHE 250 212  212 PHE PHE S . n 
E 5 251 THR 251 213  213 THR THR S . n 
E 5 252 LEU 252 214  214 LEU LEU S . n 
E 5 253 THR 253 215  215 THR THR S . n 
E 5 254 ILE 254 216  216 ILE ILE S . n 
E 5 255 SER 255 217  217 SER SER S . n 
E 5 256 ARG 256 218  218 ARG ARG S . n 
E 5 257 LEU 257 219  219 LEU LEU S . n 
E 5 258 GLU 258 220  220 GLU GLU S . n 
E 5 259 ALA 259 221  221 ALA ALA S . n 
E 5 260 GLU 260 222  222 GLU GLU S . n 
E 5 261 ASP 261 223  223 ASP ASP S . n 
E 5 262 VAL 262 224  224 VAL VAL S . n 
E 5 263 GLY 263 225  225 GLY GLY S . n 
E 5 264 VAL 264 226  226 VAL VAL S . n 
E 5 265 TYR 265 227  227 TYR TYR S . n 
E 5 266 TYR 266 228  228 TYR TYR S . n 
E 5 267 CYS 267 229  229 CYS CYS S . n 
E 5 268 MET 268 230  230 MET MET S . n 
E 5 269 GLN 269 231  231 GLN GLN S . n 
E 5 270 HIS 270 232  232 HIS HIS S . n 
E 5 271 LEU 271 233  233 LEU LEU S . n 
E 5 272 GLU 272 234  234 GLU GLU S . n 
E 5 273 TYR 273 235  235 TYR TYR S . n 
E 5 274 PRO 274 236  236 PRO PRO S . n 
E 5 275 LEU 275 237  237 LEU LEU S . n 
E 5 276 THR 276 238  238 THR THR S . n 
E 5 277 PHE 277 239  239 PHE PHE S . n 
E 5 278 GLY 278 240  240 GLY GLY S . n 
E 5 279 ALA 279 241  241 ALA ALA S . n 
E 5 280 GLY 280 242  242 GLY GLY S . n 
E 5 281 THR 281 243  243 THR THR S . n 
E 5 282 LYS 282 244  244 LYS LYS S . n 
E 5 283 LEU 283 245  245 LEU LEU S . n 
E 5 284 GLU 284 246  246 GLU GLU S . n 
E 5 285 LEU 285 247  247 LEU LEU S . n 
E 5 286 LYS 286 248  ?   ?   ?   S . n 
E 5 287 ALA 287 249  ?   ?   ?   S . n 
E 5 288 ALA 288 250  ?   ?   ?   S . n 
E 5 289 ALA 289 251  ?   ?   ?   S . n 
E 5 290 HIS 290 252  ?   ?   ?   S . n 
E 5 291 HIS 291 253  ?   ?   ?   S . n 
E 5 292 HIS 292 254  ?   ?   ?   S . n 
E 5 293 HIS 293 255  ?   ?   ?   S . n 
E 5 294 HIS 294 256  ?   ?   ?   S . n 
E 5 295 HIS 295 257  ?   ?   ?   S . n 
E 5 296 HIS 296 258  ?   ?   ?   S . n 
E 5 297 HIS 297 259  ?   ?   ?   S . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        UGA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   UGA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          UGA 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      UGA 
_pdbx_nonpoly_scheme.auth_mon_id     UGA 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ASP 9   ? CG  ? A ASP 9   CG  
2   1 Y 1 A ASP 9   ? OD1 ? A ASP 9   OD1 
3   1 Y 1 A ASP 9   ? OD2 ? A ASP 9   OD2 
4   1 Y 1 A GLU 25  ? CG  ? A GLU 25  CG  
5   1 Y 1 A GLU 25  ? CD  ? A GLU 25  CD  
6   1 Y 1 A GLU 25  ? OE1 ? A GLU 25  OE1 
7   1 Y 1 A GLU 25  ? OE2 ? A GLU 25  OE2 
8   1 Y 1 A GLU 28  ? CG  ? A GLU 28  CG  
9   1 Y 1 A GLU 28  ? CD  ? A GLU 28  CD  
10  1 Y 1 A GLU 28  ? OE1 ? A GLU 28  OE1 
11  1 Y 1 A GLU 28  ? OE2 ? A GLU 28  OE2 
12  1 Y 1 A LYS 29  ? CG  ? A LYS 29  CG  
13  1 Y 1 A LYS 29  ? CD  ? A LYS 29  CD  
14  1 Y 1 A LYS 29  ? CE  ? A LYS 29  CE  
15  1 Y 1 A LYS 29  ? NZ  ? A LYS 29  NZ  
16  1 Y 1 A GLU 33  ? CG  ? A GLU 33  CG  
17  1 Y 1 A GLU 33  ? CD  ? A GLU 33  CD  
18  1 Y 1 A GLU 33  ? OE1 ? A GLU 33  OE1 
19  1 Y 1 A GLU 33  ? OE2 ? A GLU 33  OE2 
20  1 Y 1 A GLU 43  ? CG  ? A GLU 43  CG  
21  1 Y 1 A GLU 43  ? CD  ? A GLU 43  CD  
22  1 Y 1 A GLU 43  ? OE1 ? A GLU 43  OE1 
23  1 Y 1 A GLU 43  ? OE2 ? A GLU 43  OE2 
24  1 Y 1 A SER 47  ? OG  ? A SER 47  OG  
25  1 Y 1 A THR 48  ? OG1 ? A THR 48  OG1 
26  1 Y 1 A THR 48  ? CG2 ? A THR 48  CG2 
27  1 Y 1 A VAL 50  ? CG1 ? A VAL 50  CG1 
28  1 Y 1 A VAL 50  ? CG2 ? A VAL 50  CG2 
29  1 Y 1 A LYS 51  ? CG  ? A LYS 51  CG  
30  1 Y 1 A LYS 51  ? CD  ? A LYS 51  CD  
31  1 Y 1 A LYS 51  ? CE  ? A LYS 51  CE  
32  1 Y 1 A LYS 51  ? NZ  ? A LYS 51  NZ  
33  1 Y 1 A ASP 193 ? CG  ? A ASP 193 CG  
34  1 Y 1 A ASP 193 ? OD1 ? A ASP 193 OD1 
35  1 Y 1 A ASP 193 ? OD2 ? A ASP 193 OD2 
36  1 Y 1 A ARG 205 ? CG  ? A ARG 205 CG  
37  1 Y 1 A ARG 205 ? CD  ? A ARG 205 CD  
38  1 Y 1 A ARG 205 ? NE  ? A ARG 205 NE  
39  1 Y 1 A ARG 205 ? CZ  ? A ARG 205 CZ  
40  1 Y 1 A ARG 205 ? NH1 ? A ARG 205 NH1 
41  1 Y 1 A ARG 205 ? NH2 ? A ARG 205 NH2 
42  1 Y 1 A GLU 207 ? CG  ? A GLU 207 CG  
43  1 Y 1 A GLU 207 ? CD  ? A GLU 207 CD  
44  1 Y 1 A GLU 207 ? OE1 ? A GLU 207 OE1 
45  1 Y 1 A GLU 207 ? OE2 ? A GLU 207 OE2 
46  1 Y 1 A LYS 209 ? CG  ? A LYS 209 CG  
47  1 Y 1 A LYS 209 ? CD  ? A LYS 209 CD  
48  1 Y 1 A LYS 209 ? CE  ? A LYS 209 CE  
49  1 Y 1 A LYS 209 ? NZ  ? A LYS 209 NZ  
50  1 Y 1 A ASP 229 ? CG  ? A ASP 229 CG  
51  1 Y 1 A ASP 229 ? OD1 ? A ASP 229 OD1 
52  1 Y 1 A ASP 229 ? OD2 ? A ASP 229 OD2 
53  1 Y 1 A ASP 231 ? CG  ? A ASP 231 CG  
54  1 Y 1 A ASP 231 ? OD1 ? A ASP 231 OD1 
55  1 Y 1 A ASP 231 ? OD2 ? A ASP 231 OD2 
56  1 Y 1 A VAL 233 ? CG1 ? A VAL 233 CG1 
57  1 Y 1 A VAL 233 ? CG2 ? A VAL 233 CG2 
58  1 Y 1 A ARG 242 ? CG  ? A ARG 242 CG  
59  1 Y 1 A ARG 242 ? CD  ? A ARG 242 CD  
60  1 Y 1 A ARG 242 ? NE  ? A ARG 242 NE  
61  1 Y 1 A ARG 242 ? CZ  ? A ARG 242 CZ  
62  1 Y 1 A ARG 242 ? NH1 ? A ARG 242 NH1 
63  1 Y 1 A ARG 242 ? NH2 ? A ARG 242 NH2 
64  1 Y 1 A GLU 245 ? CG  ? A GLU 245 CG  
65  1 Y 1 A GLU 245 ? CD  ? A GLU 245 CD  
66  1 Y 1 A GLU 245 ? OE1 ? A GLU 245 OE1 
67  1 Y 1 A GLU 245 ? OE2 ? A GLU 245 OE2 
68  1 Y 1 A LYS 248 ? CG  ? A LYS 248 CG  
69  1 Y 1 A LYS 248 ? CD  ? A LYS 248 CD  
70  1 Y 1 A LYS 248 ? CE  ? A LYS 248 CE  
71  1 Y 1 A LYS 248 ? NZ  ? A LYS 248 NZ  
72  1 Y 1 A ASP 261 ? CG  ? A ASP 261 CG  
73  1 Y 1 A ASP 261 ? OD1 ? A ASP 261 OD1 
74  1 Y 1 A ASP 261 ? OD2 ? A ASP 261 OD2 
75  1 Y 1 A SER 263 ? OG  ? A SER 263 OG  
76  1 Y 1 A ASP 272 ? CG  ? A ASP 272 CG  
77  1 Y 1 A ASP 272 ? OD1 ? A ASP 272 OD1 
78  1 Y 1 A ASP 272 ? OD2 ? A ASP 272 OD2 
79  1 Y 1 A LEU 273 ? CG  ? A LEU 273 CG  
80  1 Y 1 A LEU 273 ? CD1 ? A LEU 273 CD1 
81  1 Y 1 A LEU 273 ? CD2 ? A LEU 273 CD2 
82  1 Y 1 A GLU 275 ? CG  ? A GLU 275 CG  
83  1 Y 1 A GLU 275 ? CD  ? A GLU 275 CD  
84  1 Y 1 A GLU 275 ? OE1 ? A GLU 275 OE1 
85  1 Y 1 A GLU 275 ? OE2 ? A GLU 275 OE2 
86  1 Y 1 A GLU 276 ? CG  ? A GLU 276 CG  
87  1 Y 1 A GLU 276 ? CD  ? A GLU 276 CD  
88  1 Y 1 A GLU 276 ? OE1 ? A GLU 276 OE1 
89  1 Y 1 A GLU 276 ? OE2 ? A GLU 276 OE2 
90  1 Y 1 A LYS 279 ? CG  ? A LYS 279 CG  
91  1 Y 1 A LYS 279 ? CD  ? A LYS 279 CD  
92  1 Y 1 A LYS 279 ? CE  ? A LYS 279 CE  
93  1 Y 1 A LYS 279 ? NZ  ? A LYS 279 NZ  
94  1 Y 1 A LYS 280 ? CG  ? A LYS 280 CG  
95  1 Y 1 A LYS 280 ? CD  ? A LYS 280 CD  
96  1 Y 1 A LYS 280 ? CE  ? A LYS 280 CE  
97  1 Y 1 A LYS 280 ? NZ  ? A LYS 280 NZ  
98  1 Y 1 A SER 281 ? OG  ? A SER 281 OG  
99  1 Y 1 A THR 284 ? OG1 ? A THR 284 OG1 
100 1 Y 1 A THR 284 ? CG2 ? A THR 284 CG2 
101 1 Y 1 A CYS 286 ? SG  ? A CYS 286 SG  
102 1 Y 1 A GLU 289 ? CG  ? A GLU 289 CG  
103 1 Y 1 A GLU 289 ? CD  ? A GLU 289 CD  
104 1 Y 1 A GLU 289 ? OE1 ? A GLU 289 OE1 
105 1 Y 1 A GLU 289 ? OE2 ? A GLU 289 OE2 
106 1 Y 1 A SER 293 ? OG  ? A SER 293 OG  
107 1 Y 1 A THR 295 ? OG1 ? A THR 295 OG1 
108 1 Y 1 A THR 295 ? CG2 ? A THR 295 CG2 
109 1 Y 1 A GLU 297 ? CG  ? A GLU 297 CG  
110 1 Y 1 A GLU 297 ? CD  ? A GLU 297 CD  
111 1 Y 1 A GLU 297 ? OE1 ? A GLU 297 OE1 
112 1 Y 1 A GLU 297 ? OE2 ? A GLU 297 OE2 
113 1 Y 1 A GLU 298 ? CG  ? A GLU 298 CG  
114 1 Y 1 A GLU 298 ? CD  ? A GLU 298 CD  
115 1 Y 1 A GLU 298 ? OE1 ? A GLU 298 OE1 
116 1 Y 1 A GLU 298 ? OE2 ? A GLU 298 OE2 
117 1 Y 1 A GLN 306 ? CG  ? A GLN 306 CG  
118 1 Y 1 A GLN 306 ? CD  ? A GLN 306 CD  
119 1 Y 1 A GLN 306 ? OE1 ? A GLN 306 OE1 
120 1 Y 1 A GLN 306 ? NE2 ? A GLN 306 NE2 
121 1 Y 1 A ASP 309 ? CG  ? A ASP 309 CG  
122 1 Y 1 A ASP 309 ? OD1 ? A ASP 309 OD1 
123 1 Y 1 A ASP 309 ? OD2 ? A ASP 309 OD2 
124 1 Y 1 A ASP 315 ? CG  ? A ASP 315 CG  
125 1 Y 1 A ASP 315 ? OD1 ? A ASP 315 OD1 
126 1 Y 1 A ASP 315 ? OD2 ? A ASP 315 OD2 
127 1 Y 1 A THR 316 ? OG1 ? A THR 316 OG1 
128 1 Y 1 A THR 316 ? CG2 ? A THR 316 CG2 
129 1 Y 1 A GLU 318 ? CG  ? A GLU 318 CG  
130 1 Y 1 A GLU 318 ? CD  ? A GLU 318 CD  
131 1 Y 1 A GLU 318 ? OE1 ? A GLU 318 OE1 
132 1 Y 1 A GLU 318 ? OE2 ? A GLU 318 OE2 
133 1 Y 1 A THR 324 ? OG1 ? A THR 324 OG1 
134 1 Y 1 A THR 324 ? CG2 ? A THR 324 CG2 
135 1 Y 1 A CYS 325 ? SG  ? A CYS 325 SG  
136 1 Y 1 A THR 327 ? OG1 ? A THR 327 OG1 
137 1 Y 1 A THR 327 ? CG2 ? A THR 327 CG2 
138 1 Y 1 A THR 329 ? OG1 ? A THR 329 OG1 
139 1 Y 1 A THR 329 ? CG2 ? A THR 329 CG2 
140 1 Y 1 A LYS 330 ? CG  ? A LYS 330 CG  
141 1 Y 1 A LYS 330 ? CD  ? A LYS 330 CD  
142 1 Y 1 A LYS 330 ? CE  ? A LYS 330 CE  
143 1 Y 1 A LYS 330 ? NZ  ? A LYS 330 NZ  
144 1 Y 1 A ASP 341 ? CG  ? A ASP 341 CG  
145 1 Y 1 A ASP 341 ? OD1 ? A ASP 341 OD1 
146 1 Y 1 A ASP 341 ? OD2 ? A ASP 341 OD2 
147 1 Y 1 A LYS 349 ? CG  ? A LYS 349 CG  
148 1 Y 1 A LYS 349 ? CD  ? A LYS 349 CD  
149 1 Y 1 A LYS 349 ? CE  ? A LYS 349 CE  
150 1 Y 1 A LYS 349 ? NZ  ? A LYS 349 NZ  
151 1 Y 1 B LEU 4   ? CG  ? B LEU 15  CG  
152 1 Y 1 B LEU 4   ? CD1 ? B LEU 15  CD1 
153 1 Y 1 B LEU 4   ? CD2 ? B LEU 15  CD2 
154 1 Y 1 B ASP 5   ? CG  ? B ASP 16  CG  
155 1 Y 1 B ASP 5   ? OD1 ? B ASP 16  OD1 
156 1 Y 1 B ASP 5   ? OD2 ? B ASP 16  OD2 
157 1 Y 1 B GLN 6   ? CG  ? B GLN 17  CG  
158 1 Y 1 B GLN 6   ? CD  ? B GLN 17  CD  
159 1 Y 1 B GLN 6   ? OE1 ? B GLN 17  OE1 
160 1 Y 1 B GLN 6   ? NE2 ? B GLN 17  NE2 
161 1 Y 1 B ARG 8   ? CG  ? B ARG 19  CG  
162 1 Y 1 B ARG 8   ? CD  ? B ARG 19  CD  
163 1 Y 1 B ARG 8   ? NE  ? B ARG 19  NE  
164 1 Y 1 B ARG 8   ? CZ  ? B ARG 19  CZ  
165 1 Y 1 B ARG 8   ? NH1 ? B ARG 19  NH1 
166 1 Y 1 B ARG 8   ? NH2 ? B ARG 19  NH2 
167 1 Y 1 B GLN 9   ? CG  ? B GLN 20  CG  
168 1 Y 1 B GLN 9   ? CD  ? B GLN 20  CD  
169 1 Y 1 B GLN 9   ? OE1 ? B GLN 20  OE1 
170 1 Y 1 B GLN 9   ? NE2 ? B GLN 20  NE2 
171 1 Y 1 B GLU 12  ? CG  ? B GLU 23  CG  
172 1 Y 1 B GLU 12  ? CD  ? B GLU 23  CD  
173 1 Y 1 B GLU 12  ? OE1 ? B GLU 23  OE1 
174 1 Y 1 B GLU 12  ? OE2 ? B GLU 23  OE2 
175 1 Y 1 B GLN 13  ? CG  ? B GLN 24  CG  
176 1 Y 1 B GLN 13  ? CD  ? B GLN 24  CD  
177 1 Y 1 B GLN 13  ? OE1 ? B GLN 24  OE1 
178 1 Y 1 B GLN 13  ? NE2 ? B GLN 24  NE2 
179 1 Y 1 B LYS 15  ? CG  ? B LYS 26  CG  
180 1 Y 1 B LYS 15  ? CD  ? B LYS 26  CD  
181 1 Y 1 B LYS 15  ? CE  ? B LYS 26  CE  
182 1 Y 1 B LYS 15  ? NZ  ? B LYS 26  NZ  
183 1 Y 1 B ARG 19  ? CG  ? B ARG 30  CG  
184 1 Y 1 B ARG 19  ? CD  ? B ARG 30  CD  
185 1 Y 1 B ARG 19  ? NE  ? B ARG 30  NE  
186 1 Y 1 B ARG 19  ? CZ  ? B ARG 30  CZ  
187 1 Y 1 B ARG 19  ? NH1 ? B ARG 30  NH1 
188 1 Y 1 B ARG 19  ? NH2 ? B ARG 30  NH2 
189 1 Y 1 B LYS 23  ? CG  ? B LYS 34  CG  
190 1 Y 1 B LYS 23  ? CD  ? B LYS 34  CD  
191 1 Y 1 B LYS 23  ? CE  ? B LYS 34  CE  
192 1 Y 1 B LYS 23  ? NZ  ? B LYS 34  NZ  
193 1 Y 1 B SER 31  ? OG  ? B SER 42  OG  
194 1 Y 1 B ASN 36  ? CG  ? B ASN 47  CG  
195 1 Y 1 B ASN 36  ? OD1 ? B ASN 47  OD1 
196 1 Y 1 B ASN 36  ? ND2 ? B ASN 47  ND2 
197 1 Y 1 B ASP 38  ? CG  ? B ASP 49  CG  
198 1 Y 1 B ASP 38  ? OD1 ? B ASP 49  OD1 
199 1 Y 1 B ASP 38  ? OD2 ? B ASP 49  OD2 
200 1 Y 1 B ARG 42  ? CG  ? B ARG 53  CG  
201 1 Y 1 B ARG 42  ? CD  ? B ARG 53  CD  
202 1 Y 1 B ARG 42  ? NE  ? B ARG 53  NE  
203 1 Y 1 B ARG 42  ? CZ  ? B ARG 53  CZ  
204 1 Y 1 B ARG 42  ? NH1 ? B ARG 53  NH1 
205 1 Y 1 B ARG 42  ? NH2 ? B ARG 53  NH2 
206 1 Y 1 B ARG 46  ? CG  ? B ARG 57  CG  
207 1 Y 1 B ARG 46  ? CD  ? B ARG 57  CD  
208 1 Y 1 B ARG 46  ? NE  ? B ARG 57  NE  
209 1 Y 1 B ARG 46  ? CZ  ? B ARG 57  CZ  
210 1 Y 1 B ARG 46  ? NH1 ? B ARG 57  NH1 
211 1 Y 1 B ARG 46  ? NH2 ? B ARG 57  NH2 
212 1 Y 1 B GLU 130 ? CG  ? B GLU 141 CG  
213 1 Y 1 B GLU 130 ? CD  ? B GLU 141 CD  
214 1 Y 1 B GLU 130 ? OE1 ? B GLU 141 OE1 
215 1 Y 1 B GLU 130 ? OE2 ? B GLU 141 OE2 
216 1 Y 1 B ASP 153 ? CG  ? B ASP 164 CG  
217 1 Y 1 B ASP 153 ? OD1 ? B ASP 164 OD1 
218 1 Y 1 B ASP 153 ? OD2 ? B ASP 164 OD2 
219 1 Y 1 B GLU 172 ? CG  ? B GLU 183 CG  
220 1 Y 1 B GLU 172 ? CD  ? B GLU 183 CD  
221 1 Y 1 B GLU 172 ? OE1 ? B GLU 183 OE1 
222 1 Y 1 B GLU 172 ? OE2 ? B GLU 183 OE2 
223 1 Y 1 B ARG 197 ? CG  ? B ARG 208 CG  
224 1 Y 1 B ARG 197 ? CD  ? B ARG 208 CD  
225 1 Y 1 B ARG 197 ? NE  ? B ARG 208 NE  
226 1 Y 1 B ARG 197 ? CZ  ? B ARG 208 CZ  
227 1 Y 1 B ARG 197 ? NH1 ? B ARG 208 NH1 
228 1 Y 1 B ARG 197 ? NH2 ? B ARG 208 NH2 
229 1 Y 1 B ARG 214 ? CG  ? B ARG 225 CG  
230 1 Y 1 B ARG 214 ? CD  ? B ARG 225 CD  
231 1 Y 1 B ARG 214 ? NE  ? B ARG 225 NE  
232 1 Y 1 B ARG 214 ? CZ  ? B ARG 225 CZ  
233 1 Y 1 B ARG 214 ? NH1 ? B ARG 225 NH1 
234 1 Y 1 B ARG 214 ? NH2 ? B ARG 225 NH2 
235 1 Y 1 B GLU 215 ? CG  ? B GLU 226 CG  
236 1 Y 1 B GLU 215 ? CD  ? B GLU 226 CD  
237 1 Y 1 B GLU 215 ? OE1 ? B GLU 226 OE1 
238 1 Y 1 B GLU 215 ? OE2 ? B GLU 226 OE2 
239 1 Y 1 B GLU 226 ? CG  ? B GLU 237 CG  
240 1 Y 1 B GLU 226 ? CD  ? B GLU 237 CD  
241 1 Y 1 B GLU 226 ? OE1 ? B GLU 237 OE1 
242 1 Y 1 B GLU 226 ? OE2 ? B GLU 237 OE2 
243 1 Y 1 B ASP 258 ? CG  ? B ASP 269 CG  
244 1 Y 1 B ASP 258 ? OD1 ? B ASP 269 OD1 
245 1 Y 1 B ASP 258 ? OD2 ? B ASP 269 OD2 
246 1 Y 1 B ASN 268 ? CG  ? B ASN 279 CG  
247 1 Y 1 B ASN 268 ? OD1 ? B ASN 279 OD1 
248 1 Y 1 B ASN 268 ? ND2 ? B ASN 279 ND2 
249 1 Y 1 B ILE 270 ? CG1 ? B ILE 281 CG1 
250 1 Y 1 B ILE 270 ? CG2 ? B ILE 281 CG2 
251 1 Y 1 B ILE 270 ? CD1 ? B ILE 281 CD1 
252 1 Y 1 B ASP 312 ? CG  ? B ASP 323 CG  
253 1 Y 1 B ASP 312 ? OD1 ? B ASP 323 OD1 
254 1 Y 1 B ASP 312 ? OD2 ? B ASP 323 OD2 
255 1 Y 1 G SER 8   ? OG  ? C SER 8   OG  
256 1 Y 1 G ILE 9   ? CG1 ? C ILE 9   CG1 
257 1 Y 1 G ILE 9   ? CG2 ? C ILE 9   CG2 
258 1 Y 1 G ILE 9   ? CD1 ? C ILE 9   CD1 
259 1 Y 1 G GLN 11  ? CG  ? C GLN 11  CG  
260 1 Y 1 G GLN 11  ? CD  ? C GLN 11  CD  
261 1 Y 1 G GLN 11  ? OE1 ? C GLN 11  OE1 
262 1 Y 1 G GLN 11  ? NE2 ? C GLN 11  NE2 
263 1 Y 1 G ARG 13  ? CG  ? C ARG 13  CG  
264 1 Y 1 G ARG 13  ? CD  ? C ARG 13  CD  
265 1 Y 1 G ARG 13  ? NE  ? C ARG 13  NE  
266 1 Y 1 G ARG 13  ? CZ  ? C ARG 13  CZ  
267 1 Y 1 G ARG 13  ? NH1 ? C ARG 13  NH1 
268 1 Y 1 G ARG 13  ? NH2 ? C ARG 13  NH2 
269 1 Y 1 G LYS 14  ? CG  ? C LYS 14  CG  
270 1 Y 1 G LYS 14  ? CD  ? C LYS 14  CD  
271 1 Y 1 G LYS 14  ? CE  ? C LYS 14  CE  
272 1 Y 1 G LYS 14  ? NZ  ? C LYS 14  NZ  
273 1 Y 1 G LEU 15  ? CG  ? C LEU 15  CG  
274 1 Y 1 G LEU 15  ? CD1 ? C LEU 15  CD1 
275 1 Y 1 G LEU 15  ? CD2 ? C LEU 15  CD2 
276 1 Y 1 G GLU 17  ? CG  ? C GLU 17  CG  
277 1 Y 1 G GLU 17  ? CD  ? C GLU 17  CD  
278 1 Y 1 G GLU 17  ? OE1 ? C GLU 17  OE1 
279 1 Y 1 G GLU 17  ? OE2 ? C GLU 17  OE2 
280 1 Y 1 G LYS 20  ? CG  ? C LYS 20  CG  
281 1 Y 1 G LYS 20  ? CD  ? C LYS 20  CD  
282 1 Y 1 G LYS 20  ? CE  ? C LYS 20  CE  
283 1 Y 1 G LYS 20  ? NZ  ? C LYS 20  NZ  
284 1 Y 1 G MET 21  ? CG  ? C MET 21  CG  
285 1 Y 1 G MET 21  ? SD  ? C MET 21  SD  
286 1 Y 1 G MET 21  ? CE  ? C MET 21  CE  
287 1 Y 1 G GLU 22  ? CG  ? C GLU 22  CG  
288 1 Y 1 G GLU 22  ? CD  ? C GLU 22  CD  
289 1 Y 1 G GLU 22  ? OE1 ? C GLU 22  OE1 
290 1 Y 1 G GLU 22  ? OE2 ? C GLU 22  OE2 
291 1 Y 1 G ASP 26  ? CG  ? C ASP 26  CG  
292 1 Y 1 G ASP 26  ? OD1 ? C ASP 26  OD1 
293 1 Y 1 G ASP 26  ? OD2 ? C ASP 26  OD2 
294 1 Y 1 G LYS 32  ? CG  ? C LYS 32  CG  
295 1 Y 1 G LYS 32  ? CD  ? C LYS 32  CD  
296 1 Y 1 G LYS 32  ? CE  ? C LYS 32  CE  
297 1 Y 1 G LYS 32  ? NZ  ? C LYS 32  NZ  
298 1 Y 1 G GLU 42  ? CG  ? C GLU 42  CG  
299 1 Y 1 G GLU 42  ? CD  ? C GLU 42  CD  
300 1 Y 1 G GLU 42  ? OE1 ? C GLU 42  OE1 
301 1 Y 1 G GLU 42  ? OE2 ? C GLU 42  OE2 
302 1 Y 1 G LYS 46  ? CG  ? C LYS 46  CG  
303 1 Y 1 G LYS 46  ? CD  ? C LYS 46  CD  
304 1 Y 1 G LYS 46  ? CE  ? C LYS 46  CE  
305 1 Y 1 G LYS 46  ? NZ  ? C LYS 46  NZ  
306 1 Y 1 G GLU 47  ? CG  ? C GLU 47  CG  
307 1 Y 1 G GLU 47  ? CD  ? C GLU 47  CD  
308 1 Y 1 G GLU 47  ? OE1 ? C GLU 47  OE1 
309 1 Y 1 G GLU 47  ? OE2 ? C GLU 47  OE2 
310 1 Y 1 G GLU 58  ? CG  ? C GLU 58  CG  
311 1 Y 1 G GLU 58  ? CD  ? C GLU 58  CD  
312 1 Y 1 G GLU 58  ? OE1 ? C GLU 58  OE1 
313 1 Y 1 G GLU 58  ? OE2 ? C GLU 58  OE2 
314 1 Y 1 R ILE 24  ? CG1 ? D ILE 187 CG1 
315 1 Y 1 R ILE 24  ? CG2 ? D ILE 187 CG2 
316 1 Y 1 R ILE 24  ? CD1 ? D ILE 187 CD1 
317 1 Y 1 R MET 31  ? CG  ? D MET 194 CG  
318 1 Y 1 R MET 31  ? SD  ? D MET 194 SD  
319 1 Y 1 R MET 31  ? CE  ? D MET 194 CE  
320 1 Y 1 R PHE 48  ? CG  ? D PHE 211 CG  
321 1 Y 1 R PHE 48  ? CD1 ? D PHE 211 CD1 
322 1 Y 1 R PHE 48  ? CD2 ? D PHE 211 CD2 
323 1 Y 1 R PHE 48  ? CE1 ? D PHE 211 CE1 
324 1 Y 1 R PHE 48  ? CE2 ? D PHE 211 CE2 
325 1 Y 1 R PHE 48  ? CZ  ? D PHE 211 CZ  
326 1 Y 1 R LYS 54  ? CG  ? D LYS 217 CG  
327 1 Y 1 R LYS 54  ? CD  ? D LYS 217 CD  
328 1 Y 1 R LYS 54  ? CE  ? D LYS 217 CE  
329 1 Y 1 R LYS 54  ? NZ  ? D LYS 217 NZ  
330 1 Y 1 R LEU 84  ? CG  ? D LEU 247 CG  
331 1 Y 1 R LEU 84  ? CD1 ? D LEU 247 CD1 
332 1 Y 1 R LEU 84  ? CD2 ? D LEU 247 CD2 
333 1 Y 1 R GLN 88  ? CG  ? D GLN 251 CG  
334 1 Y 1 R GLN 88  ? CD  ? D GLN 251 CD  
335 1 Y 1 R GLN 88  ? OE1 ? D GLN 251 OE1 
336 1 Y 1 R GLN 88  ? NE2 ? D GLN 251 NE2 
337 1 Y 1 R ARG 95  ? CG  ? D ARG 258 CG  
338 1 Y 1 R ARG 95  ? CD  ? D ARG 258 CD  
339 1 Y 1 R ARG 95  ? NE  ? D ARG 258 NE  
340 1 Y 1 R ARG 95  ? CZ  ? D ARG 258 CZ  
341 1 Y 1 R ARG 95  ? NH1 ? D ARG 258 NH1 
342 1 Y 1 R ARG 95  ? NH2 ? D ARG 258 NH2 
343 1 Y 1 R LYS 122 ? CG  ? D LYS 285 CG  
344 1 Y 1 R LYS 122 ? CD  ? D LYS 285 CD  
345 1 Y 1 R LYS 122 ? CE  ? D LYS 285 CE  
346 1 Y 1 R LYS 122 ? NZ  ? D LYS 285 NZ  
347 1 Y 1 R LEU 127 ? CG  ? D LEU 290 CG  
348 1 Y 1 R LEU 127 ? CD1 ? D LEU 290 CD1 
349 1 Y 1 R LEU 127 ? CD2 ? D LEU 290 CD2 
350 1 Y 1 R THR 129 ? OG1 ? D THR 292 OG1 
351 1 Y 1 R THR 129 ? CG2 ? D THR 292 CG2 
352 1 Y 1 R SER 130 ? OG  ? D SER 293 OG  
353 1 Y 1 R PHE 131 ? CG  ? D PHE 294 CG  
354 1 Y 1 R PHE 131 ? CD1 ? D PHE 294 CD1 
355 1 Y 1 R PHE 131 ? CD2 ? D PHE 294 CD2 
356 1 Y 1 R PHE 131 ? CE1 ? D PHE 294 CE1 
357 1 Y 1 R PHE 131 ? CE2 ? D PHE 294 CE2 
358 1 Y 1 R PHE 131 ? CZ  ? D PHE 294 CZ  
359 1 Y 1 R ILE 132 ? CG1 ? D ILE 295 CG1 
360 1 Y 1 R ILE 132 ? CG2 ? D ILE 295 CG2 
361 1 Y 1 R ILE 132 ? CD1 ? D ILE 295 CD1 
362 1 Y 1 R VAL 135 ? CG1 ? D VAL 298 CG1 
363 1 Y 1 R VAL 135 ? CG2 ? D VAL 298 CG2 
364 1 Y 1 R SER 136 ? OG  ? D SER 299 OG  
365 1 Y 1 R TYR 137 ? CG  ? D TYR 300 CG  
366 1 Y 1 R TYR 137 ? CD1 ? D TYR 300 CD1 
367 1 Y 1 R TYR 137 ? CD2 ? D TYR 300 CD2 
368 1 Y 1 R TYR 137 ? CE1 ? D TYR 300 CE1 
369 1 Y 1 R TYR 137 ? CE2 ? D TYR 300 CE2 
370 1 Y 1 R TYR 137 ? CZ  ? D TYR 300 CZ  
371 1 Y 1 R TYR 137 ? OH  ? D TYR 300 OH  
372 1 Y 1 R LEU 140 ? CG  ? D LEU 303 CG  
373 1 Y 1 R LEU 140 ? CD1 ? D LEU 303 CD1 
374 1 Y 1 R LEU 140 ? CD2 ? D LEU 303 CD2 
375 1 Y 1 R ILE 144 ? CG1 ? D ILE 307 CG1 
376 1 Y 1 R ILE 144 ? CG2 ? D ILE 307 CG2 
377 1 Y 1 R ILE 144 ? CD1 ? D ILE 307 CD1 
378 1 Y 1 R LEU 148 ? CG  ? D LEU 311 CG  
379 1 Y 1 R LEU 148 ? CD1 ? D LEU 311 CD1 
380 1 Y 1 R LEU 148 ? CD2 ? D LEU 311 CD2 
381 1 Y 1 R LEU 150 ? CG  ? D LEU 313 CG  
382 1 Y 1 R LEU 150 ? CD1 ? D LEU 313 CD1 
383 1 Y 1 R LEU 150 ? CD2 ? D LEU 313 CD2 
384 1 Y 1 R LEU 151 ? CG  ? D LEU 314 CG  
385 1 Y 1 R LEU 151 ? CD1 ? D LEU 314 CD1 
386 1 Y 1 R LEU 151 ? CD2 ? D LEU 314 CD2 
387 1 Y 1 R VAL 154 ? CG1 ? D VAL 317 CG1 
388 1 Y 1 R VAL 154 ? CG2 ? D VAL 317 CG2 
389 1 Y 1 R ASN 161 ? CG  ? D ASN 324 CG  
390 1 Y 1 R ASN 161 ? OD1 ? D ASN 324 OD1 
391 1 Y 1 R ASN 161 ? ND2 ? D ASN 324 ND2 
392 1 Y 1 R VAL 164 ? CG1 ? D VAL 327 CG1 
393 1 Y 1 R VAL 164 ? CG2 ? D VAL 327 CG2 
394 1 Y 1 R ARG 165 ? CG  ? D ARG 328 CG  
395 1 Y 1 R ARG 165 ? CD  ? D ARG 328 CD  
396 1 Y 1 R ARG 165 ? NE  ? D ARG 328 NE  
397 1 Y 1 R ARG 165 ? CZ  ? D ARG 328 CZ  
398 1 Y 1 R ARG 165 ? NH1 ? D ARG 328 NH1 
399 1 Y 1 R ARG 165 ? NH2 ? D ARG 328 NH2 
400 1 Y 1 R GLU 166 ? CG  ? D GLU 329 CG  
401 1 Y 1 R GLU 166 ? CD  ? D GLU 329 CD  
402 1 Y 1 R GLU 166 ? OE1 ? D GLU 329 OE1 
403 1 Y 1 R GLU 166 ? OE2 ? D GLU 329 OE2 
404 1 Y 1 R VAL 167 ? CG1 ? D VAL 330 CG1 
405 1 Y 1 R VAL 167 ? CG2 ? D VAL 330 CG2 
406 1 Y 1 R THR 168 ? OG1 ? D THR 331 OG1 
407 1 Y 1 R THR 168 ? CG2 ? D THR 331 CG2 
408 1 Y 1 R GLN 169 ? CG  ? D GLN 332 CG  
409 1 Y 1 R GLN 169 ? CD  ? D GLN 332 CD  
410 1 Y 1 R GLN 169 ? OE1 ? D GLN 332 OE1 
411 1 Y 1 R GLN 169 ? NE2 ? D GLN 332 NE2 
412 1 Y 1 R ILE 170 ? CG1 ? D ILE 333 CG1 
413 1 Y 1 R ILE 170 ? CG2 ? D ILE 333 CG2 
414 1 Y 1 R ILE 170 ? CD1 ? D ILE 333 CD1 
415 1 Y 1 R GLU 174 ? CG  ? D GLU 337 CG  
416 1 Y 1 R GLU 174 ? CD  ? D GLU 337 CD  
417 1 Y 1 R GLU 174 ? OE1 ? D GLU 337 OE1 
418 1 Y 1 R GLU 174 ? OE2 ? D GLU 337 OE2 
419 1 Y 1 R GLU 178 ? CG  ? D GLU 341 CG  
420 1 Y 1 R GLU 178 ? CD  ? D GLU 341 CD  
421 1 Y 1 R GLU 178 ? OE1 ? D GLU 341 OE1 
422 1 Y 1 R GLU 178 ? OE2 ? D GLU 341 OE2 
423 1 Y 1 R ARG 181 ? CG  ? D ARG 344 CG  
424 1 Y 1 R ARG 181 ? CD  ? D ARG 344 CD  
425 1 Y 1 R ARG 181 ? NE  ? D ARG 344 NE  
426 1 Y 1 R ARG 181 ? CZ  ? D ARG 344 CZ  
427 1 Y 1 R ARG 181 ? NH1 ? D ARG 344 NH1 
428 1 Y 1 R ARG 181 ? NH2 ? D ARG 344 NH2 
429 1 Y 1 R LYS 182 ? CG  ? D LYS 345 CG  
430 1 Y 1 R LYS 182 ? CD  ? D LYS 345 CD  
431 1 Y 1 R LYS 182 ? CE  ? D LYS 345 CE  
432 1 Y 1 R LYS 182 ? NZ  ? D LYS 345 NZ  
433 1 Y 1 R LEU 200 ? CG  ? D LEU 363 CG  
434 1 Y 1 R LEU 200 ? CD1 ? D LEU 363 CD1 
435 1 Y 1 R LEU 200 ? CD2 ? D LEU 363 CD2 
436 1 Y 1 R LYS 215 ? CG  ? D LYS 378 CG  
437 1 Y 1 R LYS 215 ? CD  ? D LYS 378 CD  
438 1 Y 1 R LYS 215 ? CE  ? D LYS 378 CE  
439 1 Y 1 R LYS 215 ? NZ  ? D LYS 378 NZ  
440 1 Y 1 R LEU 218 ? CG  ? D LEU 381 CG  
441 1 Y 1 R LEU 218 ? CD1 ? D LEU 381 CD1 
442 1 Y 1 R LEU 218 ? CD2 ? D LEU 381 CD2 
443 1 Y 1 R LYS 219 ? CG  ? D LYS 382 CG  
444 1 Y 1 R LYS 219 ? CD  ? D LYS 382 CD  
445 1 Y 1 R LYS 219 ? CE  ? D LYS 382 CE  
446 1 Y 1 R LYS 219 ? NZ  ? D LYS 382 NZ  
447 1 Y 1 R SER 220 ? OG  ? D SER 383 OG  
448 1 Y 1 R SER 221 ? OG  ? D SER 384 OG  
449 1 Y 1 R ARG 222 ? CG  ? D ARG 385 CG  
450 1 Y 1 R ARG 222 ? CD  ? D ARG 385 CD  
451 1 Y 1 R ARG 222 ? NE  ? D ARG 385 NE  
452 1 Y 1 R ARG 222 ? CZ  ? D ARG 385 CZ  
453 1 Y 1 R ARG 222 ? NH1 ? D ARG 385 NH1 
454 1 Y 1 R ARG 222 ? NH2 ? D ARG 385 NH2 
455 1 Y 1 R LYS 229 ? CG  ? D LYS 392 CG  
456 1 Y 1 R LYS 229 ? CD  ? D LYS 392 CD  
457 1 Y 1 R LYS 229 ? CE  ? D LYS 392 CE  
458 1 Y 1 R LYS 229 ? NZ  ? D LYS 392 NZ  
459 1 Y 1 R LYS 230 ? CG  ? D LYS 393 CG  
460 1 Y 1 R LYS 230 ? CD  ? D LYS 393 CD  
461 1 Y 1 R LYS 230 ? CE  ? D LYS 393 CE  
462 1 Y 1 R LYS 230 ? NZ  ? D LYS 393 NZ  
463 1 Y 1 R ARG 233 ? CG  ? D ARG 396 CG  
464 1 Y 1 R ARG 233 ? CD  ? D ARG 396 CD  
465 1 Y 1 R ARG 233 ? NE  ? D ARG 396 NE  
466 1 Y 1 R ARG 233 ? CZ  ? D ARG 396 CZ  
467 1 Y 1 R ARG 233 ? NH1 ? D ARG 396 NH1 
468 1 Y 1 R ARG 233 ? NH2 ? D ARG 396 NH2 
469 1 Y 1 R GLU 262 ? CG  ? D GLU 425 CG  
470 1 Y 1 R GLU 262 ? CD  ? D GLU 425 CD  
471 1 Y 1 R GLU 262 ? OE1 ? D GLU 425 OE1 
472 1 Y 1 R GLU 262 ? OE2 ? D GLU 425 OE2 
473 1 Y 1 R GLN 268 ? CG  ? D GLN 431 CG  
474 1 Y 1 R GLN 268 ? CD  ? D GLN 431 CD  
475 1 Y 1 R GLN 268 ? OE1 ? D GLN 431 OE1 
476 1 Y 1 R GLN 268 ? NE2 ? D GLN 431 NE2 
477 1 Y 1 R LYS 270 ? CG  ? D LYS 433 CG  
478 1 Y 1 R LYS 270 ? CD  ? D LYS 433 CD  
479 1 Y 1 R LYS 270 ? CE  ? D LYS 433 CE  
480 1 Y 1 R LYS 270 ? NZ  ? D LYS 433 NZ  
481 1 Y 1 R PHE 297 ? CG  ? D PHE 460 CG  
482 1 Y 1 R PHE 297 ? CD1 ? D PHE 460 CD1 
483 1 Y 1 R PHE 297 ? CD2 ? D PHE 460 CD2 
484 1 Y 1 R PHE 297 ? CE1 ? D PHE 460 CE1 
485 1 Y 1 R PHE 297 ? CE2 ? D PHE 460 CE2 
486 1 Y 1 R PHE 297 ? CZ  ? D PHE 460 CZ  
487 1 Y 1 R CYS 307 ? SG  ? D CYS 470 SG  
488 1 Y 1 R LYS 308 ? CG  ? D LYS 471 CG  
489 1 Y 1 R LYS 308 ? CD  ? D LYS 471 CD  
490 1 Y 1 R LYS 308 ? CE  ? D LYS 471 CE  
491 1 Y 1 R LYS 308 ? NZ  ? D LYS 471 NZ  
492 1 Y 1 R LYS 309 ? CG  ? D LYS 472 CG  
493 1 Y 1 R LYS 309 ? CD  ? D LYS 472 CD  
494 1 Y 1 R LYS 309 ? CE  ? D LYS 472 CE  
495 1 Y 1 R LYS 309 ? NZ  ? D LYS 472 NZ  
496 1 Y 1 S SER 7   ? OG  ? E SER 45  OG  
497 1 Y 1 S SER 21  ? OG  ? E SER 59  OG  
498 1 Y 1 S SER 52  ? OG  ? E SER 90  OG  
499 1 Y 1 S ASP 62  ? CG  ? E ASP 100 CG  
500 1 Y 1 S ASP 62  ? OD1 ? E ASP 100 OD1 
501 1 Y 1 S ASP 62  ? OD2 ? E ASP 100 OD2 
502 1 Y 1 S LYS 65  ? CG  ? E LYS 103 CG  
503 1 Y 1 S LYS 65  ? CD  ? E LYS 103 CD  
504 1 Y 1 S LYS 65  ? CE  ? E LYS 103 CE  
505 1 Y 1 S LYS 65  ? NZ  ? E LYS 103 NZ  
506 1 Y 1 S SER 88  ? OG  ? E SER 126 OG  
507 1 Y 1 S THR 144 ? OG1 ? E THR 182 OG1 
508 1 Y 1 S THR 144 ? CG2 ? E THR 182 CG2 
509 1 Y 1 S SER 154 ? OG  ? E SER 192 OG  
510 1 Y 1 S THR 215 ? OG1 ? E THR 253 OG1 
511 1 Y 1 S THR 215 ? CG2 ? E THR 253 CG2 
512 1 Y 1 S GLU 246 ? CG  ? E GLU 284 CG  
513 1 Y 1 S GLU 246 ? CD  ? E GLU 284 CD  
514 1 Y 1 S GLU 246 ? OE1 ? E GLU 284 OE1 
515 1 Y 1 S GLU 246 ? OE2 ? E GLU 284 OE2 
516 1 Y 1 S LEU 247 ? CG  ? E LEU 285 CG  
517 1 Y 1 S LEU 247 ? CD1 ? E LEU 285 CD1 
518 1 Y 1 S LEU 247 ? CD2 ? E LEU 285 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9J0I 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9J0I 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9J0I 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9J0I 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.76 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 8721  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.457 ? 11877 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 9.021 ? 1237  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 1382  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 1491  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9J0I 
_struct.title                        'UDP-Glucuronic acid bound purinergic receptor P2Y14 complex with Gi' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9J0I 
_struct_keywords.text            'Complex, MEMBRANE PROTEIN/IMMUNE SYSTEM, MEMBRANE PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI1_HUMAN P63096 ? 1 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1  
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2  
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1  
4 UNP C562_ECOLX  P0ABE7 ? 4 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23 
5 UNP P2Y14_HUMAN Q15391 ? 4 
;INSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGD
SGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTN
QSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFV
FFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLD
ISRIKRGNTTLESTDTL
;
2  
6 PDB 9J0I        9J0I   ? 5 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9J0I A 1   ? 354 ? P63096 1   ? 354 ? 1    354 
2 2 9J0I B 13  ? 351 ? P62873 2   ? 340 ? 2    340 
3 3 9J0I G 1   ? 71  ? P59768 1   ? 71  ? 1    71  
4 4 9J0I R 48  ? 152 ? P0ABE7 23  ? 127 ? -115 -11 
5 5 9J0I R 165 ? 501 ? Q15391 2   ? 338 ? 2    338 
6 6 9J0I S 1   ? 297 ? 9J0I   -37 ? 259 ? -37  259 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9J0I MET B 1   ? UNP P62873 ?   ?   'initiating methionine' -10  1  
2 9J0I HIS B 2   ? UNP P62873 ?   ?   'expression tag'        -9   2  
2 9J0I HIS B 3   ? UNP P62873 ?   ?   'expression tag'        -8   3  
2 9J0I HIS B 4   ? UNP P62873 ?   ?   'expression tag'        -7   4  
2 9J0I HIS B 5   ? UNP P62873 ?   ?   'expression tag'        -6   5  
2 9J0I HIS B 6   ? UNP P62873 ?   ?   'expression tag'        -5   6  
2 9J0I HIS B 7   ? UNP P62873 ?   ?   'expression tag'        -4   7  
2 9J0I GLY B 8   ? UNP P62873 ?   ?   'expression tag'        -3   8  
2 9J0I SER B 9   ? UNP P62873 ?   ?   'expression tag'        -2   9  
2 9J0I LEU B 10  ? UNP P62873 ?   ?   'expression tag'        -1   10 
2 9J0I LEU B 11  ? UNP P62873 ?   ?   'expression tag'        0    11 
2 9J0I GLN B 12  ? UNP P62873 ?   ?   'expression tag'        1    12 
2 9J0I GLY B 352 ? UNP P62873 ?   ?   'expression tag'        341  13 
2 9J0I SER B 353 ? UNP P62873 ?   ?   'expression tag'        342  14 
2 9J0I SER B 354 ? UNP P62873 ?   ?   'expression tag'        343  15 
2 9J0I GLY B 355 ? UNP P62873 ?   ?   'expression tag'        344  16 
2 9J0I GLY B 356 ? UNP P62873 ?   ?   'expression tag'        345  17 
2 9J0I GLY B 357 ? UNP P62873 ?   ?   'expression tag'        346  18 
2 9J0I GLY B 358 ? UNP P62873 ?   ?   'expression tag'        347  19 
2 9J0I SER B 359 ? UNP P62873 ?   ?   'expression tag'        348  20 
2 9J0I GLY B 360 ? UNP P62873 ?   ?   'expression tag'        349  21 
2 9J0I GLY B 361 ? UNP P62873 ?   ?   'expression tag'        350  22 
2 9J0I GLY B 362 ? UNP P62873 ?   ?   'expression tag'        351  23 
2 9J0I GLY B 363 ? UNP P62873 ?   ?   'expression tag'        352  24 
2 9J0I SER B 364 ? UNP P62873 ?   ?   'expression tag'        353  25 
2 9J0I SER B 365 ? UNP P62873 ?   ?   'expression tag'        354  26 
2 9J0I GLY B 366 ? UNP P62873 ?   ?   'expression tag'        355  27 
2 9J0I VAL B 367 ? UNP P62873 ?   ?   'expression tag'        356  28 
2 9J0I SER B 368 ? UNP P62873 ?   ?   'expression tag'        357  29 
2 9J0I GLY B 369 ? UNP P62873 ?   ?   'expression tag'        358  30 
2 9J0I TRP B 370 ? UNP P62873 ?   ?   'expression tag'        359  31 
2 9J0I ARG B 371 ? UNP P62873 ?   ?   'expression tag'        360  32 
2 9J0I LEU B 372 ? UNP P62873 ?   ?   'expression tag'        361  33 
2 9J0I PHE B 373 ? UNP P62873 ?   ?   'expression tag'        362  34 
2 9J0I LYS B 374 ? UNP P62873 ?   ?   'expression tag'        363  35 
2 9J0I LYS B 375 ? UNP P62873 ?   ?   'expression tag'        364  36 
2 9J0I ILE B 376 ? UNP P62873 ?   ?   'expression tag'        365  37 
2 9J0I SER B 377 ? UNP P62873 ?   ?   'expression tag'        366  38 
4 9J0I MET R 1   ? UNP P0ABE7 ?   ?   'initiating methionine' -162 39 
4 9J0I LYS R 2   ? UNP P0ABE7 ?   ?   'expression tag'        -161 40 
4 9J0I THR R 3   ? UNP P0ABE7 ?   ?   'expression tag'        -160 41 
4 9J0I ILE R 4   ? UNP P0ABE7 ?   ?   'expression tag'        -159 42 
4 9J0I ILE R 5   ? UNP P0ABE7 ?   ?   'expression tag'        -158 43 
4 9J0I ALA R 6   ? UNP P0ABE7 ?   ?   'expression tag'        -157 44 
4 9J0I LEU R 7   ? UNP P0ABE7 ?   ?   'expression tag'        -156 45 
4 9J0I SER R 8   ? UNP P0ABE7 ?   ?   'expression tag'        -155 46 
4 9J0I TYR R 9   ? UNP P0ABE7 ?   ?   'expression tag'        -154 47 
4 9J0I ILE R 10  ? UNP P0ABE7 ?   ?   'expression tag'        -153 48 
4 9J0I PHE R 11  ? UNP P0ABE7 ?   ?   'expression tag'        -152 49 
4 9J0I CYS R 12  ? UNP P0ABE7 ?   ?   'expression tag'        -151 50 
4 9J0I LEU R 13  ? UNP P0ABE7 ?   ?   'expression tag'        -150 51 
4 9J0I VAL R 14  ? UNP P0ABE7 ?   ?   'expression tag'        -149 52 
4 9J0I PHE R 15  ? UNP P0ABE7 ?   ?   'expression tag'        -148 53 
4 9J0I ALA R 16  ? UNP P0ABE7 ?   ?   'expression tag'        -147 54 
4 9J0I ASP R 17  ? UNP P0ABE7 ?   ?   'expression tag'        -146 55 
4 9J0I TYR R 18  ? UNP P0ABE7 ?   ?   'expression tag'        -145 56 
4 9J0I LYS R 19  ? UNP P0ABE7 ?   ?   'expression tag'        -144 57 
4 9J0I ASP R 20  ? UNP P0ABE7 ?   ?   'expression tag'        -143 58 
4 9J0I ASP R 21  ? UNP P0ABE7 ?   ?   'expression tag'        -142 59 
4 9J0I ASP R 22  ? UNP P0ABE7 ?   ?   'expression tag'        -141 60 
4 9J0I ASP R 23  ? UNP P0ABE7 ?   ?   'expression tag'        -140 61 
4 9J0I ALA R 24  ? UNP P0ABE7 ?   ?   'expression tag'        -139 62 
4 9J0I GLY R 25  ? UNP P0ABE7 ?   ?   'expression tag'        -138 63 
4 9J0I ARG R 26  ? UNP P0ABE7 ?   ?   'expression tag'        -137 64 
4 9J0I ALA R 27  ? UNP P0ABE7 ?   ?   'expression tag'        -136 65 
4 9J0I HIS R 28  ? UNP P0ABE7 ?   ?   'expression tag'        -135 66 
4 9J0I HIS R 29  ? UNP P0ABE7 ?   ?   'expression tag'        -134 67 
4 9J0I HIS R 30  ? UNP P0ABE7 ?   ?   'expression tag'        -133 68 
4 9J0I HIS R 31  ? UNP P0ABE7 ?   ?   'expression tag'        -132 69 
4 9J0I HIS R 32  ? UNP P0ABE7 ?   ?   'expression tag'        -131 70 
4 9J0I HIS R 33  ? UNP P0ABE7 ?   ?   'expression tag'        -130 71 
4 9J0I HIS R 34  ? UNP P0ABE7 ?   ?   'expression tag'        -129 72 
4 9J0I HIS R 35  ? UNP P0ABE7 ?   ?   'expression tag'        -128 73 
4 9J0I HIS R 36  ? UNP P0ABE7 ?   ?   'expression tag'        -127 74 
4 9J0I HIS R 37  ? UNP P0ABE7 ?   ?   'expression tag'        -126 75 
4 9J0I GLU R 38  ? UNP P0ABE7 ?   ?   'expression tag'        -125 76 
4 9J0I ASN R 39  ? UNP P0ABE7 ?   ?   'expression tag'        -124 77 
4 9J0I LEU R 40  ? UNP P0ABE7 ?   ?   'expression tag'        -123 78 
4 9J0I TYR R 41  ? UNP P0ABE7 ?   ?   'expression tag'        -122 79 
4 9J0I PHE R 42  ? UNP P0ABE7 ?   ?   'expression tag'        -121 80 
4 9J0I GLN R 43  ? UNP P0ABE7 ?   ?   'expression tag'        -120 81 
4 9J0I SER R 44  ? UNP P0ABE7 ?   ?   'expression tag'        -119 82 
4 9J0I GLY R 45  ? UNP P0ABE7 ?   ?   'expression tag'        -118 83 
4 9J0I ALA R 46  ? UNP P0ABE7 ?   ?   'expression tag'        -117 84 
4 9J0I PRO R 47  ? UNP P0ABE7 ?   ?   'expression tag'        -116 85 
4 9J0I TRP R 54  ? UNP P0ABE7 MET 29  conflict                -109 86 
4 9J0I ILE R 149 ? UNP P0ABE7 HIS 124 conflict                -14  87 
4 9J0I LEU R 153 ? UNP P0ABE7 ?   ?   linker                  -10  88 
4 9J0I GLU R 154 ? UNP P0ABE7 ?   ?   linker                  -9   89 
4 9J0I PHE R 155 ? UNP P0ABE7 ?   ?   linker                  -8   90 
4 9J0I LEU R 156 ? UNP P0ABE7 ?   ?   linker                  -7   91 
4 9J0I GLU R 157 ? UNP P0ABE7 ?   ?   linker                  -6   92 
4 9J0I VAL R 158 ? UNP P0ABE7 ?   ?   linker                  -5   93 
4 9J0I LEU R 159 ? UNP P0ABE7 ?   ?   linker                  -4   94 
4 9J0I PHE R 160 ? UNP P0ABE7 ?   ?   linker                  -3   95 
4 9J0I GLN R 161 ? UNP P0ABE7 ?   ?   linker                  -2   96 
4 9J0I GLY R 162 ? UNP P0ABE7 ?   ?   linker                  -1   97 
4 9J0I PRO R 163 ? UNP P0ABE7 ?   ?   linker                  0    98 
4 9J0I ALA R 164 ? UNP P0ABE7 ?   ?   linker                  1    99 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ARG A 32  ? SER A 6   ARG A 32  1 ? 27 
HELX_P HELX_P2  AA2 GLY A 45  ? MET A 53  ? GLY A 45  MET A 53  1 ? 9  
HELX_P HELX_P3  AA3 GLU A 207 ? GLU A 216 ? GLU A 207 GLU A 216 5 ? 10 
HELX_P HELX_P4  AA4 SER A 228 ? LEU A 232 ? SER A 228 LEU A 232 5 ? 5  
HELX_P HELX_P5  AA5 ASN A 241 ? ASN A 255 ? ASN A 241 ASN A 255 1 ? 15 
HELX_P HELX_P6  AA6 LYS A 270 ? LYS A 279 ? LYS A 270 LYS A 279 1 ? 10 
HELX_P HELX_P7  AA7 PRO A 282 ? CYS A 286 ? PRO A 282 CYS A 286 5 ? 5  
HELX_P HELX_P8  AA8 THR A 295 ? ASP A 309 ? THR A 295 ASP A 309 1 ? 15 
HELX_P HELX_P9  AA9 THR A 329 ? CYS A 351 ? THR A 329 CYS A 351 1 ? 23 
HELX_P HELX_P10 AB1 ASP B 16  ? ALA B 37  ? ASP B 5   ALA B 26  1 ? 22 
HELX_P HELX_P11 AB2 THR B 40  ? THR B 45  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P12 AB3 ASN B 46  ? ILE B 48  ? ASN B 35  ILE B 37  5 ? 3  
HELX_P HELX_P13 AB4 SER C 8   ? ASN C 24  ? SER G 8   ASN G 24  1 ? 17 
HELX_P HELX_P14 AB5 LYS C 29  ? ALA C 45  ? LYS G 29  ALA G 45  1 ? 17 
HELX_P HELX_P15 AB6 LYS C 46  ? ASP C 48  ? LYS G 46  ASP G 48  5 ? 3  
HELX_P HELX_P16 AB7 PRO C 55  ? ASN C 59  ? PRO G 55  ASN G 59  5 ? 5  
HELX_P HELX_P17 AB8 GLN D 186 ? PHE D 211 ? GLN R 23  PHE R 48  1 ? 26 
HELX_P HELX_P18 AB9 LYS D 217 ? GLY D 246 ? LYS R 54  GLY R 83  1 ? 30 
HELX_P HELX_P19 AC1 PRO D 249 ? VAL D 259 ? PRO R 86  VAL R 96  1 ? 11 
HELX_P HELX_P20 AC2 VAL D 259 ? LYS D 288 ? VAL R 96  LYS R 125 1 ? 30 
HELX_P HELX_P21 AC3 TRP D 291 ? ILE D 295 ? TRP R 128 ILE R 132 5 ? 5  
HELX_P HELX_P22 AC4 SER D 299 ? LEU D 322 ? SER R 136 LEU R 159 1 ? 24 
HELX_P HELX_P23 AC5 CYS D 335 ? LYS D 339 ? CYS R 172 LYS R 176 5 ? 5  
HELX_P HELX_P24 AC6 SER D 340 ? LYS D 378 ? SER R 177 LYS R 215 1 ? 39 
HELX_P HELX_P25 AC7 SER D 384 ? GLN D 423 ? SER R 221 GLN R 260 1 ? 40 
HELX_P HELX_P26 AC8 SER D 429 ? TYR D 458 ? SER R 266 TYR R 295 1 ? 30 
HELX_P HELX_P27 AC9 CYS D 462 ? HIS D 474 ? CYS R 299 HIS R 311 1 ? 13 
HELX_P HELX_P28 AD1 ALA E 66  ? PHE E 70  ? ALA S 28  PHE S 32  5 ? 5  
HELX_P HELX_P29 AD2 SER E 91  ? GLY E 94  ? SER S 53  GLY S 56  5 ? 4  
HELX_P HELX_P30 AD3 ARG E 125 ? THR E 129 ? ARG S 87  THR S 91  5 ? 5  
HELX_P HELX_P31 AD4 GLU E 258 ? VAL E 262 ? GLU S 220 VAL S 224 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 257 SG ? ? ? 1_555 D CYS 335 SG ? ? R CYS 94 R CYS 172 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ? ? E CYS 60  SG ? ? ? 1_555 E CYS 134 SG ? ? S CYS 22 S CYS 96  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 257 ? CYS D 335 ? CYS R 94 ? 1_555 CYS R 172 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 60  ? CYS E 134 ? CYS S 22 ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 185 ? PHE A 191 ? VAL A 185 PHE A 191 
AA1 2 LEU A 194 ? ASP A 200 ? LEU A 194 ASP A 200 
AA1 3 VAL A 34  ? GLY A 40  ? VAL A 34  GLY A 40  
AA1 4 ALA A 220 ? ALA A 226 ? ALA A 220 ALA A 226 
AA1 5 SER A 263 ? ASN A 269 ? SER A 263 ASN A 269 
AA1 6 ILE A 319 ? PHE A 323 ? ILE A 319 PHE A 323 
AA2 1 ARG B 57  ? ARG B 63  ? ARG B 46  ARG B 52  
AA2 2 PHE B 346 ? ASN B 351 ? PHE B 335 ASN B 340 
AA2 3 VAL B 338 ? SER B 342 ? VAL B 327 SER B 331 
AA2 4 VAL B 326 ? VAL B 331 ? VAL B 315 VAL B 320 
AA3 1 ILE B 69  ? TRP B 74  ? ILE B 58  TRP B 63  
AA3 2 LEU B 80  ? SER B 85  ? LEU B 69  SER B 74  
AA3 3 LYS B 89  ? ASP B 94  ? LYS B 78  ASP B 83  
AA3 4 ASN B 99  ? PRO B 105 ? ASN B 88  PRO B 94  
AA4 1 VAL B 111 ? TYR B 116 ? VAL B 100 TYR B 105 
AA4 2 TYR B 122 ? GLY B 127 ? TYR B 111 GLY B 116 
AA4 3 ILE B 131 ? ASN B 136 ? ILE B 120 ASN B 125 
AA4 4 ARG B 145 ? ALA B 151 ? ARG B 134 ALA B 140 
AA5 1 LEU B 157 ? PHE B 162 ? LEU B 146 PHE B 151 
AA5 2 GLN B 167 ? SER B 172 ? GLN B 156 SER B 161 
AA5 3 THR B 176 ? ASP B 181 ? THR B 165 ASP B 170 
AA5 4 GLN B 186 ? THR B 192 ? GLN B 175 THR B 181 
AA6 1 VAL B 198 ? LEU B 203 ? VAL B 187 LEU B 192 
AA6 2 LEU B 209 ? ALA B 214 ? LEU B 198 ALA B 203 
AA6 3 SER B 218 ? ASP B 223 ? SER B 207 ASP B 212 
AA6 4 CYS B 229 ? THR B 234 ? CYS B 218 THR B 223 
AA7 1 ILE B 240 ? PHE B 245 ? ILE B 229 PHE B 234 
AA7 2 ALA B 251 ? SER B 256 ? ALA B 240 SER B 245 
AA7 3 CYS B 261 ? ASP B 265 ? CYS B 250 ASP B 254 
AA7 4 GLN B 270 ? TYR B 275 ? GLN B 259 TYR B 264 
AA8 1 ILE B 284 ? PHE B 289 ? ILE B 273 PHE B 278 
AA8 2 LEU B 295 ? TYR B 300 ? LEU B 284 TYR B 289 
AA8 3 CYS B 305 ? ASP B 309 ? CYS B 294 ASP B 298 
AA8 4 ARG B 315 ? LEU B 319 ? ARG B 304 LEU B 308 
AA9 1 GLN E 41  ? SER E 45  ? GLN S 3   SER S 7   
AA9 2 ARG E 56  ? SER E 63  ? ARG S 18  SER S 25  
AA9 3 THR E 116 ? MET E 121 ? THR S 78  MET S 83  
AA9 4 PHE E 106 ? ASP E 111 ? PHE S 68  ASP S 73  
AB1 1 GLY E 48  ? VAL E 50  ? GLY S 10  VAL S 12  
AB1 2 THR E 153 ? VAL E 157 ? THR S 115 VAL S 119 
AB1 3 ALA E 130 ? SER E 137 ? ALA S 92  SER S 99  
AB1 4 GLY E 71  ? ALA E 78  ? GLY S 33  ALA S 40  
AB1 5 GLY E 82  ? ILE E 89  ? GLY S 44  ILE S 51  
AB1 6 ILE E 96  ? TYR E 98  ? ILE S 58  TYR S 60  
AB2 1 GLY E 48  ? VAL E 50  ? GLY S 10  VAL S 12  
AB2 2 THR E 153 ? VAL E 157 ? THR S 115 VAL S 119 
AB2 3 ALA E 130 ? SER E 137 ? ALA S 92  SER S 99  
AB2 4 PHE E 148 ? TRP E 149 ? PHE S 110 TRP S 111 
AB3 1 MET E 178 ? GLN E 180 ? MET S 140 GLN S 142 
AB3 2 VAL E 193 ? SER E 199 ? VAL S 155 SER S 161 
AB3 3 ALA E 249 ? ILE E 254 ? ALA S 211 ILE S 216 
AB3 4 PHE E 241 ? GLY E 245 ? PHE S 203 GLY S 207 
AB4 1 SER E 184 ? PRO E 186 ? SER S 146 PRO S 148 
AB4 2 THR E 281 ? GLU E 284 ? THR S 243 GLU S 246 
AB4 3 VAL E 264 ? GLN E 269 ? VAL S 226 GLN S 231 
AB4 4 LEU E 212 ? GLN E 217 ? LEU S 174 GLN S 179 
AB4 5 GLN E 224 ? TYR E 228 ? GLN S 186 TYR S 190 
AB4 6 ASN E 232 ? LEU E 233 ? ASN S 194 LEU S 195 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 189 ? N PHE A 189 O PHE A 196 ? O PHE A 196 
AA1 2 3 O PHE A 199 ? O PHE A 199 N LEU A 36  ? N LEU A 36  
AA1 3 4 N LEU A 39  ? N LEU A 39  O ILE A 222 ? O ILE A 222 
AA1 4 5 N VAL A 225 ? N VAL A 225 O PHE A 267 ? O PHE A 267 
AA1 5 6 N LEU A 266 ? N LEU A 266 O HIS A 322 ? O HIS A 322 
AA2 1 2 N LEU B 62  ? N LEU B 51  O LEU B 347 ? O LEU B 336 
AA2 2 3 O LYS B 348 ? O LYS B 337 N THR B 340 ? N THR B 329 
AA2 3 4 O GLY B 341 ? O GLY B 330 N CYS B 328 ? N CYS B 317 
AA3 1 2 N ALA B 71  ? N ALA B 60  O ALA B 84  ? O ALA B 73  
AA3 2 3 N LEU B 81  ? N LEU B 70  O TRP B 93  ? O TRP B 82  
AA3 3 4 N ASP B 94  ? N ASP B 83  O ASN B 99  ? O ASN B 88  
AA4 1 2 N ALA B 115 ? N ALA B 104 O ALA B 124 ? O ALA B 113 
AA4 2 3 N VAL B 123 ? N VAL B 112 O TYR B 135 ? O TYR B 124 
AA4 3 4 N ILE B 134 ? N ILE B 123 O SER B 147 ? O SER B 136 
AA5 1 2 N CYS B 159 ? N CYS B 148 O SER B 171 ? O SER B 160 
AA5 2 3 N ILE B 168 ? N ILE B 157 O TRP B 180 ? O TRP B 169 
AA5 3 4 N CYS B 177 ? N CYS B 166 O PHE B 191 ? O PHE B 180 
AA6 1 2 N MET B 199 ? N MET B 188 O GLY B 213 ? O GLY B 202 
AA6 2 3 N PHE B 210 ? N PHE B 199 O TRP B 222 ? O TRP B 211 
AA6 3 4 N ALA B 219 ? N ALA B 208 O PHE B 233 ? O PHE B 222 
AA7 1 2 N CYS B 244 ? N CYS B 233 O ALA B 253 ? O ALA B 242 
AA7 2 3 N PHE B 252 ? N PHE B 241 O PHE B 264 ? O PHE B 253 
AA7 3 4 N LEU B 263 ? N LEU B 252 O LEU B 272 ? O LEU B 261 
AA8 1 2 N SER B 288 ? N SER B 277 O LEU B 297 ? O LEU B 286 
AA8 2 3 N LEU B 296 ? N LEU B 285 O TRP B 308 ? O TRP B 297 
AA8 3 4 N VAL B 307 ? N VAL B 296 O GLY B 317 ? O GLY B 306 
AA9 1 2 N GLN E 41  ? N GLN S 3   O SER E 63  ? O SER S 25  
AA9 2 3 N ARG E 56  ? N ARG S 18  O MET E 121 ? O MET S 83  
AA9 3 4 O THR E 116 ? O THR S 78  N ASP E 111 ? N ASP S 73  
AB1 1 2 N GLY E 48  ? N GLY S 10  O THR E 156 ? O THR S 118 
AB1 2 3 O LEU E 155 ? O LEU S 117 N ALA E 130 ? N ALA S 92  
AB1 3 4 O MET E 131 ? O MET S 93  N GLN E 77  ? N GLN S 39  
AB1 4 5 N ARG E 76  ? N ARG S 38  O GLU E 84  ? O GLU S 46  
AB1 5 6 N TYR E 88  ? N TYR S 50  O TYR E 97  ? O TYR S 59  
AB2 1 2 N GLY E 48  ? N GLY S 10  O THR E 156 ? O THR S 118 
AB2 2 3 O LEU E 155 ? O LEU S 117 N ALA E 130 ? N ALA S 92  
AB2 3 4 N ARG E 136 ? N ARG S 98  O PHE E 148 ? O PHE S 110 
AB3 1 2 N THR E 179 ? N THR S 141 O ARG E 198 ? O ARG S 160 
AB3 2 3 N CYS E 197 ? N CYS S 159 O PHE E 250 ? O PHE S 212 
AB3 3 4 O THR E 253 ? O THR S 215 N SER E 242 ? N SER S 204 
AB4 1 2 N VAL E 185 ? N VAL S 147 O LYS E 282 ? O LYS S 244 
AB4 2 3 O THR E 281 ? O THR S 243 N TYR E 265 ? N TYR S 227 
AB4 3 4 O VAL E 264 ? O VAL S 226 N GLN E 217 ? N GLN S 179 
AB4 4 5 N LEU E 216 ? N LEU S 178 O GLN E 224 ? O GLN S 186 
AB4 5 6 N TYR E 228 ? N TYR S 190 O ASN E 232 ? O ASN S 194 
# 
_pdbx_entry_details.entry_id                   9J0I 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   R TYR 265 ? ? OG R SER 269 ? ? 2.12 
2 1 OE2 A GLU 8   ? ? OH S TYR 175 ? ? 2.15 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE R 20  ? ? -90.24  -60.10  
2  1 VAL R 96  ? ? -122.40 -58.48  
3  1 LYS R 125 ? ? 55.23   72.66   
4  1 TRP R 128 ? ? -99.22  37.26   
5  1 LYS R 219 ? ? 63.09   -151.05 
6  1 SER R 266 ? ? 66.82   164.05  
7  1 MET S 192 ? ? 72.95   -10.52  
8  1 ASP S 201 ? ? -68.32  5.05    
9  1 ARG S 218 ? ? 39.25   54.85   
10 1 PRO S 236 ? ? -65.12  78.80   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9J0I 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9J0I 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.76 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               127175 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.50 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 Complex 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9J0I 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_experiment.entry_id                9J0I 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1   
2   1 Y 1 A GLY 2    ? A GLY 2   
3   1 Y 1 A LYS 54   ? A LYS 54  
4   1 Y 1 A ILE 55   ? A ILE 55  
5   1 Y 1 A ILE 56   ? A ILE 56  
6   1 Y 1 A HIS 57   ? A HIS 57  
7   1 Y 1 A GLU 58   ? A GLU 58  
8   1 Y 1 A ALA 59   ? A ALA 59  
9   1 Y 1 A GLY 60   ? A GLY 60  
10  1 Y 1 A TYR 61   ? A TYR 61  
11  1 Y 1 A SER 62   ? A SER 62  
12  1 Y 1 A GLU 63   ? A GLU 63  
13  1 Y 1 A GLU 64   ? A GLU 64  
14  1 Y 1 A GLU 65   ? A GLU 65  
15  1 Y 1 A CYS 66   ? A CYS 66  
16  1 Y 1 A LYS 67   ? A LYS 67  
17  1 Y 1 A GLN 68   ? A GLN 68  
18  1 Y 1 A TYR 69   ? A TYR 69  
19  1 Y 1 A LYS 70   ? A LYS 70  
20  1 Y 1 A ALA 71   ? A ALA 71  
21  1 Y 1 A VAL 72   ? A VAL 72  
22  1 Y 1 A VAL 73   ? A VAL 73  
23  1 Y 1 A TYR 74   ? A TYR 74  
24  1 Y 1 A SER 75   ? A SER 75  
25  1 Y 1 A ASN 76   ? A ASN 76  
26  1 Y 1 A THR 77   ? A THR 77  
27  1 Y 1 A ILE 78   ? A ILE 78  
28  1 Y 1 A GLN 79   ? A GLN 79  
29  1 Y 1 A SER 80   ? A SER 80  
30  1 Y 1 A ILE 81   ? A ILE 81  
31  1 Y 1 A ILE 82   ? A ILE 82  
32  1 Y 1 A ALA 83   ? A ALA 83  
33  1 Y 1 A ILE 84   ? A ILE 84  
34  1 Y 1 A ILE 85   ? A ILE 85  
35  1 Y 1 A ARG 86   ? A ARG 86  
36  1 Y 1 A ALA 87   ? A ALA 87  
37  1 Y 1 A MET 88   ? A MET 88  
38  1 Y 1 A GLY 89   ? A GLY 89  
39  1 Y 1 A ARG 90   ? A ARG 90  
40  1 Y 1 A LEU 91   ? A LEU 91  
41  1 Y 1 A LYS 92   ? A LYS 92  
42  1 Y 1 A ILE 93   ? A ILE 93  
43  1 Y 1 A ASP 94   ? A ASP 94  
44  1 Y 1 A PHE 95   ? A PHE 95  
45  1 Y 1 A GLY 96   ? A GLY 96  
46  1 Y 1 A ASP 97   ? A ASP 97  
47  1 Y 1 A SER 98   ? A SER 98  
48  1 Y 1 A ALA 99   ? A ALA 99  
49  1 Y 1 A ARG 100  ? A ARG 100 
50  1 Y 1 A ALA 101  ? A ALA 101 
51  1 Y 1 A ASP 102  ? A ASP 102 
52  1 Y 1 A ASP 103  ? A ASP 103 
53  1 Y 1 A ALA 104  ? A ALA 104 
54  1 Y 1 A ARG 105  ? A ARG 105 
55  1 Y 1 A GLN 106  ? A GLN 106 
56  1 Y 1 A LEU 107  ? A LEU 107 
57  1 Y 1 A PHE 108  ? A PHE 108 
58  1 Y 1 A VAL 109  ? A VAL 109 
59  1 Y 1 A LEU 110  ? A LEU 110 
60  1 Y 1 A ALA 111  ? A ALA 111 
61  1 Y 1 A GLY 112  ? A GLY 112 
62  1 Y 1 A ALA 113  ? A ALA 113 
63  1 Y 1 A ALA 114  ? A ALA 114 
64  1 Y 1 A GLU 115  ? A GLU 115 
65  1 Y 1 A GLU 116  ? A GLU 116 
66  1 Y 1 A GLY 117  ? A GLY 117 
67  1 Y 1 A PHE 118  ? A PHE 118 
68  1 Y 1 A MET 119  ? A MET 119 
69  1 Y 1 A THR 120  ? A THR 120 
70  1 Y 1 A ALA 121  ? A ALA 121 
71  1 Y 1 A GLU 122  ? A GLU 122 
72  1 Y 1 A LEU 123  ? A LEU 123 
73  1 Y 1 A ALA 124  ? A ALA 124 
74  1 Y 1 A GLY 125  ? A GLY 125 
75  1 Y 1 A VAL 126  ? A VAL 126 
76  1 Y 1 A ILE 127  ? A ILE 127 
77  1 Y 1 A LYS 128  ? A LYS 128 
78  1 Y 1 A ARG 129  ? A ARG 129 
79  1 Y 1 A LEU 130  ? A LEU 130 
80  1 Y 1 A TRP 131  ? A TRP 131 
81  1 Y 1 A LYS 132  ? A LYS 132 
82  1 Y 1 A ASP 133  ? A ASP 133 
83  1 Y 1 A SER 134  ? A SER 134 
84  1 Y 1 A GLY 135  ? A GLY 135 
85  1 Y 1 A VAL 136  ? A VAL 136 
86  1 Y 1 A GLN 137  ? A GLN 137 
87  1 Y 1 A ALA 138  ? A ALA 138 
88  1 Y 1 A CYS 139  ? A CYS 139 
89  1 Y 1 A PHE 140  ? A PHE 140 
90  1 Y 1 A ASN 141  ? A ASN 141 
91  1 Y 1 A ARG 142  ? A ARG 142 
92  1 Y 1 A SER 143  ? A SER 143 
93  1 Y 1 A ARG 144  ? A ARG 144 
94  1 Y 1 A GLU 145  ? A GLU 145 
95  1 Y 1 A TYR 146  ? A TYR 146 
96  1 Y 1 A GLN 147  ? A GLN 147 
97  1 Y 1 A LEU 148  ? A LEU 148 
98  1 Y 1 A ASN 149  ? A ASN 149 
99  1 Y 1 A ASP 150  ? A ASP 150 
100 1 Y 1 A SER 151  ? A SER 151 
101 1 Y 1 A ALA 152  ? A ALA 152 
102 1 Y 1 A ALA 153  ? A ALA 153 
103 1 Y 1 A TYR 154  ? A TYR 154 
104 1 Y 1 A TYR 155  ? A TYR 155 
105 1 Y 1 A LEU 156  ? A LEU 156 
106 1 Y 1 A ASN 157  ? A ASN 157 
107 1 Y 1 A ASP 158  ? A ASP 158 
108 1 Y 1 A LEU 159  ? A LEU 159 
109 1 Y 1 A ASP 160  ? A ASP 160 
110 1 Y 1 A ARG 161  ? A ARG 161 
111 1 Y 1 A ILE 162  ? A ILE 162 
112 1 Y 1 A ALA 163  ? A ALA 163 
113 1 Y 1 A GLN 164  ? A GLN 164 
114 1 Y 1 A PRO 165  ? A PRO 165 
115 1 Y 1 A ASN 166  ? A ASN 166 
116 1 Y 1 A TYR 167  ? A TYR 167 
117 1 Y 1 A ILE 168  ? A ILE 168 
118 1 Y 1 A PRO 169  ? A PRO 169 
119 1 Y 1 A THR 170  ? A THR 170 
120 1 Y 1 A GLN 171  ? A GLN 171 
121 1 Y 1 A GLN 172  ? A GLN 172 
122 1 Y 1 A ASP 173  ? A ASP 173 
123 1 Y 1 A VAL 174  ? A VAL 174 
124 1 Y 1 A LEU 175  ? A LEU 175 
125 1 Y 1 A ARG 176  ? A ARG 176 
126 1 Y 1 A THR 177  ? A THR 177 
127 1 Y 1 A ARG 178  ? A ARG 178 
128 1 Y 1 A VAL 179  ? A VAL 179 
129 1 Y 1 A LYS 180  ? A LYS 180 
130 1 Y 1 A THR 181  ? A THR 181 
131 1 Y 1 A ALA 235  ? A ALA 235 
132 1 Y 1 A GLU 236  ? A GLU 236 
133 1 Y 1 A ASP 237  ? A ASP 237 
134 1 Y 1 A GLU 238  ? A GLU 238 
135 1 Y 1 A GLU 239  ? A GLU 239 
136 1 Y 1 B MET -10  ? B MET 1   
137 1 Y 1 B HIS -9   ? B HIS 2   
138 1 Y 1 B HIS -8   ? B HIS 3   
139 1 Y 1 B HIS -7   ? B HIS 4   
140 1 Y 1 B HIS -6   ? B HIS 5   
141 1 Y 1 B HIS -5   ? B HIS 6   
142 1 Y 1 B HIS -4   ? B HIS 7   
143 1 Y 1 B GLY -3   ? B GLY 8   
144 1 Y 1 B SER -2   ? B SER 9   
145 1 Y 1 B LEU -1   ? B LEU 10  
146 1 Y 1 B LEU 0    ? B LEU 11  
147 1 Y 1 B GLN 1    ? B GLN 12  
148 1 Y 1 B SER 2    ? B SER 13  
149 1 Y 1 B GLU 3    ? B GLU 14  
150 1 Y 1 B GLY 341  ? B GLY 352 
151 1 Y 1 B SER 342  ? B SER 353 
152 1 Y 1 B SER 343  ? B SER 354 
153 1 Y 1 B GLY 344  ? B GLY 355 
154 1 Y 1 B GLY 345  ? B GLY 356 
155 1 Y 1 B GLY 346  ? B GLY 357 
156 1 Y 1 B GLY 347  ? B GLY 358 
157 1 Y 1 B SER 348  ? B SER 359 
158 1 Y 1 B GLY 349  ? B GLY 360 
159 1 Y 1 B GLY 350  ? B GLY 361 
160 1 Y 1 B GLY 351  ? B GLY 362 
161 1 Y 1 B GLY 352  ? B GLY 363 
162 1 Y 1 B SER 353  ? B SER 364 
163 1 Y 1 B SER 354  ? B SER 365 
164 1 Y 1 B GLY 355  ? B GLY 366 
165 1 Y 1 B VAL 356  ? B VAL 367 
166 1 Y 1 B SER 357  ? B SER 368 
167 1 Y 1 B GLY 358  ? B GLY 369 
168 1 Y 1 B TRP 359  ? B TRP 370 
169 1 Y 1 B ARG 360  ? B ARG 371 
170 1 Y 1 B LEU 361  ? B LEU 372 
171 1 Y 1 B PHE 362  ? B PHE 373 
172 1 Y 1 B LYS 363  ? B LYS 374 
173 1 Y 1 B LYS 364  ? B LYS 375 
174 1 Y 1 B ILE 365  ? B ILE 376 
175 1 Y 1 B SER 366  ? B SER 377 
176 1 Y 1 G MET 1    ? C MET 1   
177 1 Y 1 G ALA 2    ? C ALA 2   
178 1 Y 1 G SER 3    ? C SER 3   
179 1 Y 1 G ASN 4    ? C ASN 4   
180 1 Y 1 G ASN 5    ? C ASN 5   
181 1 Y 1 G THR 6    ? C THR 6   
182 1 Y 1 G GLU 63   ? C GLU 63  
183 1 Y 1 G LYS 64   ? C LYS 64  
184 1 Y 1 G LYS 65   ? C LYS 65  
185 1 Y 1 G PHE 66   ? C PHE 66  
186 1 Y 1 G PHE 67   ? C PHE 67  
187 1 Y 1 G CYS 68   ? C CYS 68  
188 1 Y 1 G ALA 69   ? C ALA 69  
189 1 Y 1 G ILE 70   ? C ILE 70  
190 1 Y 1 G LEU 71   ? C LEU 71  
191 1 Y 1 R MET -162 ? D MET 1   
192 1 Y 1 R LYS -161 ? D LYS 2   
193 1 Y 1 R THR -160 ? D THR 3   
194 1 Y 1 R ILE -159 ? D ILE 4   
195 1 Y 1 R ILE -158 ? D ILE 5   
196 1 Y 1 R ALA -157 ? D ALA 6   
197 1 Y 1 R LEU -156 ? D LEU 7   
198 1 Y 1 R SER -155 ? D SER 8   
199 1 Y 1 R TYR -154 ? D TYR 9   
200 1 Y 1 R ILE -153 ? D ILE 10  
201 1 Y 1 R PHE -152 ? D PHE 11  
202 1 Y 1 R CYS -151 ? D CYS 12  
203 1 Y 1 R LEU -150 ? D LEU 13  
204 1 Y 1 R VAL -149 ? D VAL 14  
205 1 Y 1 R PHE -148 ? D PHE 15  
206 1 Y 1 R ALA -147 ? D ALA 16  
207 1 Y 1 R ASP -146 ? D ASP 17  
208 1 Y 1 R TYR -145 ? D TYR 18  
209 1 Y 1 R LYS -144 ? D LYS 19  
210 1 Y 1 R ASP -143 ? D ASP 20  
211 1 Y 1 R ASP -142 ? D ASP 21  
212 1 Y 1 R ASP -141 ? D ASP 22  
213 1 Y 1 R ASP -140 ? D ASP 23  
214 1 Y 1 R ALA -139 ? D ALA 24  
215 1 Y 1 R GLY -138 ? D GLY 25  
216 1 Y 1 R ARG -137 ? D ARG 26  
217 1 Y 1 R ALA -136 ? D ALA 27  
218 1 Y 1 R HIS -135 ? D HIS 28  
219 1 Y 1 R HIS -134 ? D HIS 29  
220 1 Y 1 R HIS -133 ? D HIS 30  
221 1 Y 1 R HIS -132 ? D HIS 31  
222 1 Y 1 R HIS -131 ? D HIS 32  
223 1 Y 1 R HIS -130 ? D HIS 33  
224 1 Y 1 R HIS -129 ? D HIS 34  
225 1 Y 1 R HIS -128 ? D HIS 35  
226 1 Y 1 R HIS -127 ? D HIS 36  
227 1 Y 1 R HIS -126 ? D HIS 37  
228 1 Y 1 R GLU -125 ? D GLU 38  
229 1 Y 1 R ASN -124 ? D ASN 39  
230 1 Y 1 R LEU -123 ? D LEU 40  
231 1 Y 1 R TYR -122 ? D TYR 41  
232 1 Y 1 R PHE -121 ? D PHE 42  
233 1 Y 1 R GLN -120 ? D GLN 43  
234 1 Y 1 R SER -119 ? D SER 44  
235 1 Y 1 R GLY -118 ? D GLY 45  
236 1 Y 1 R ALA -117 ? D ALA 46  
237 1 Y 1 R PRO -116 ? D PRO 47  
238 1 Y 1 R ALA -115 ? D ALA 48  
239 1 Y 1 R ASP -114 ? D ASP 49  
240 1 Y 1 R LEU -113 ? D LEU 50  
241 1 Y 1 R GLU -112 ? D GLU 51  
242 1 Y 1 R ASP -111 ? D ASP 52  
243 1 Y 1 R ASN -110 ? D ASN 53  
244 1 Y 1 R TRP -109 ? D TRP 54  
245 1 Y 1 R GLU -108 ? D GLU 55  
246 1 Y 1 R THR -107 ? D THR 56  
247 1 Y 1 R LEU -106 ? D LEU 57  
248 1 Y 1 R ASN -105 ? D ASN 58  
249 1 Y 1 R ASP -104 ? D ASP 59  
250 1 Y 1 R ASN -103 ? D ASN 60  
251 1 Y 1 R LEU -102 ? D LEU 61  
252 1 Y 1 R LYS -101 ? D LYS 62  
253 1 Y 1 R VAL -100 ? D VAL 63  
254 1 Y 1 R ILE -99  ? D ILE 64  
255 1 Y 1 R GLU -98  ? D GLU 65  
256 1 Y 1 R LYS -97  ? D LYS 66  
257 1 Y 1 R ALA -96  ? D ALA 67  
258 1 Y 1 R ASP -95  ? D ASP 68  
259 1 Y 1 R ASN -94  ? D ASN 69  
260 1 Y 1 R ALA -93  ? D ALA 70  
261 1 Y 1 R ALA -92  ? D ALA 71  
262 1 Y 1 R GLN -91  ? D GLN 72  
263 1 Y 1 R VAL -90  ? D VAL 73  
264 1 Y 1 R LYS -89  ? D LYS 74  
265 1 Y 1 R ASP -88  ? D ASP 75  
266 1 Y 1 R ALA -87  ? D ALA 76  
267 1 Y 1 R LEU -86  ? D LEU 77  
268 1 Y 1 R THR -85  ? D THR 78  
269 1 Y 1 R LYS -84  ? D LYS 79  
270 1 Y 1 R MET -83  ? D MET 80  
271 1 Y 1 R ARG -82  ? D ARG 81  
272 1 Y 1 R ALA -81  ? D ALA 82  
273 1 Y 1 R ALA -80  ? D ALA 83  
274 1 Y 1 R ALA -79  ? D ALA 84  
275 1 Y 1 R LEU -78  ? D LEU 85  
276 1 Y 1 R ASP -77  ? D ASP 86  
277 1 Y 1 R ALA -76  ? D ALA 87  
278 1 Y 1 R GLN -75  ? D GLN 88  
279 1 Y 1 R LYS -74  ? D LYS 89  
280 1 Y 1 R ALA -73  ? D ALA 90  
281 1 Y 1 R THR -72  ? D THR 91  
282 1 Y 1 R PRO -71  ? D PRO 92  
283 1 Y 1 R PRO -70  ? D PRO 93  
284 1 Y 1 R LYS -69  ? D LYS 94  
285 1 Y 1 R LEU -68  ? D LEU 95  
286 1 Y 1 R GLU -67  ? D GLU 96  
287 1 Y 1 R ASP -66  ? D ASP 97  
288 1 Y 1 R LYS -65  ? D LYS 98  
289 1 Y 1 R SER -64  ? D SER 99  
290 1 Y 1 R PRO -63  ? D PRO 100 
291 1 Y 1 R ASP -62  ? D ASP 101 
292 1 Y 1 R SER -61  ? D SER 102 
293 1 Y 1 R PRO -60  ? D PRO 103 
294 1 Y 1 R GLU -59  ? D GLU 104 
295 1 Y 1 R MET -58  ? D MET 105 
296 1 Y 1 R LYS -57  ? D LYS 106 
297 1 Y 1 R ASP -56  ? D ASP 107 
298 1 Y 1 R PHE -55  ? D PHE 108 
299 1 Y 1 R ARG -54  ? D ARG 109 
300 1 Y 1 R HIS -53  ? D HIS 110 
301 1 Y 1 R GLY -52  ? D GLY 111 
302 1 Y 1 R PHE -51  ? D PHE 112 
303 1 Y 1 R ASP -50  ? D ASP 113 
304 1 Y 1 R ILE -49  ? D ILE 114 
305 1 Y 1 R LEU -48  ? D LEU 115 
306 1 Y 1 R VAL -47  ? D VAL 116 
307 1 Y 1 R GLY -46  ? D GLY 117 
308 1 Y 1 R GLN -45  ? D GLN 118 
309 1 Y 1 R ILE -44  ? D ILE 119 
310 1 Y 1 R ASP -43  ? D ASP 120 
311 1 Y 1 R ASP -42  ? D ASP 121 
312 1 Y 1 R ALA -41  ? D ALA 122 
313 1 Y 1 R LEU -40  ? D LEU 123 
314 1 Y 1 R LYS -39  ? D LYS 124 
315 1 Y 1 R LEU -38  ? D LEU 125 
316 1 Y 1 R ALA -37  ? D ALA 126 
317 1 Y 1 R ASN -36  ? D ASN 127 
318 1 Y 1 R GLU -35  ? D GLU 128 
319 1 Y 1 R GLY -34  ? D GLY 129 
320 1 Y 1 R LYS -33  ? D LYS 130 
321 1 Y 1 R VAL -32  ? D VAL 131 
322 1 Y 1 R LYS -31  ? D LYS 132 
323 1 Y 1 R GLU -30  ? D GLU 133 
324 1 Y 1 R ALA -29  ? D ALA 134 
325 1 Y 1 R GLN -28  ? D GLN 135 
326 1 Y 1 R ALA -27  ? D ALA 136 
327 1 Y 1 R ALA -26  ? D ALA 137 
328 1 Y 1 R ALA -25  ? D ALA 138 
329 1 Y 1 R GLU -24  ? D GLU 139 
330 1 Y 1 R GLN -23  ? D GLN 140 
331 1 Y 1 R LEU -22  ? D LEU 141 
332 1 Y 1 R LYS -21  ? D LYS 142 
333 1 Y 1 R THR -20  ? D THR 143 
334 1 Y 1 R THR -19  ? D THR 144 
335 1 Y 1 R ARG -18  ? D ARG 145 
336 1 Y 1 R ASN -17  ? D ASN 146 
337 1 Y 1 R ALA -16  ? D ALA 147 
338 1 Y 1 R TYR -15  ? D TYR 148 
339 1 Y 1 R ILE -14  ? D ILE 149 
340 1 Y 1 R GLN -13  ? D GLN 150 
341 1 Y 1 R LYS -12  ? D LYS 151 
342 1 Y 1 R TYR -11  ? D TYR 152 
343 1 Y 1 R LEU -10  ? D LEU 153 
344 1 Y 1 R GLU -9   ? D GLU 154 
345 1 Y 1 R PHE -8   ? D PHE 155 
346 1 Y 1 R LEU -7   ? D LEU 156 
347 1 Y 1 R GLU -6   ? D GLU 157 
348 1 Y 1 R VAL -5   ? D VAL 158 
349 1 Y 1 R LEU -4   ? D LEU 159 
350 1 Y 1 R PHE -3   ? D PHE 160 
351 1 Y 1 R GLN -2   ? D GLN 161 
352 1 Y 1 R GLY -1   ? D GLY 162 
353 1 Y 1 R PRO 0    ? D PRO 163 
354 1 Y 1 R ALA 1    ? D ALA 164 
355 1 Y 1 R ILE 2    ? D ILE 165 
356 1 Y 1 R ASN 3    ? D ASN 166 
357 1 Y 1 R SER 4    ? D SER 167 
358 1 Y 1 R THR 5    ? D THR 168 
359 1 Y 1 R SER 6    ? D SER 169 
360 1 Y 1 R THR 7    ? D THR 170 
361 1 Y 1 R GLN 8    ? D GLN 171 
362 1 Y 1 R PRO 9    ? D PRO 172 
363 1 Y 1 R PRO 10   ? D PRO 173 
364 1 Y 1 R ASP 11   ? D ASP 174 
365 1 Y 1 R GLU 12   ? D GLU 175 
366 1 Y 1 R SER 13   ? D SER 176 
367 1 Y 1 R CYS 14   ? D CYS 177 
368 1 Y 1 R ILE 312  ? D ILE 475 
369 1 Y 1 R PRO 313  ? D PRO 476 
370 1 Y 1 R LEU 314  ? D LEU 477 
371 1 Y 1 R LYS 315  ? D LYS 478 
372 1 Y 1 R ALA 316  ? D ALA 479 
373 1 Y 1 R GLN 317  ? D GLN 480 
374 1 Y 1 R ASN 318  ? D ASN 481 
375 1 Y 1 R ASP 319  ? D ASP 482 
376 1 Y 1 R LEU 320  ? D LEU 483 
377 1 Y 1 R ASP 321  ? D ASP 484 
378 1 Y 1 R ILE 322  ? D ILE 485 
379 1 Y 1 R SER 323  ? D SER 486 
380 1 Y 1 R ARG 324  ? D ARG 487 
381 1 Y 1 R ILE 325  ? D ILE 488 
382 1 Y 1 R LYS 326  ? D LYS 489 
383 1 Y 1 R ARG 327  ? D ARG 490 
384 1 Y 1 R GLY 328  ? D GLY 491 
385 1 Y 1 R ASN 329  ? D ASN 492 
386 1 Y 1 R THR 330  ? D THR 493 
387 1 Y 1 R THR 331  ? D THR 494 
388 1 Y 1 R LEU 332  ? D LEU 495 
389 1 Y 1 R GLU 333  ? D GLU 496 
390 1 Y 1 R SER 334  ? D SER 497 
391 1 Y 1 R THR 335  ? D THR 498 
392 1 Y 1 R ASP 336  ? D ASP 499 
393 1 Y 1 R THR 337  ? D THR 500 
394 1 Y 1 R LEU 338  ? D LEU 501 
395 1 Y 1 S MET -37  ? E MET 1   
396 1 Y 1 S LEU -36  ? E LEU 2   
397 1 Y 1 S LEU -35  ? E LEU 3   
398 1 Y 1 S VAL -34  ? E VAL 4   
399 1 Y 1 S ASN -33  ? E ASN 5   
400 1 Y 1 S GLN -32  ? E GLN 6   
401 1 Y 1 S SER -31  ? E SER 7   
402 1 Y 1 S HIS -30  ? E HIS 8   
403 1 Y 1 S GLN -29  ? E GLN 9   
404 1 Y 1 S GLY -28  ? E GLY 10  
405 1 Y 1 S PHE -27  ? E PHE 11  
406 1 Y 1 S ASN -26  ? E ASN 12  
407 1 Y 1 S LYS -25  ? E LYS 13  
408 1 Y 1 S GLU -24  ? E GLU 14  
409 1 Y 1 S HIS -23  ? E HIS 15  
410 1 Y 1 S THR -22  ? E THR 16  
411 1 Y 1 S SER -21  ? E SER 17  
412 1 Y 1 S LYS -20  ? E LYS 18  
413 1 Y 1 S MET -19  ? E MET 19  
414 1 Y 1 S VAL -18  ? E VAL 20  
415 1 Y 1 S SER -17  ? E SER 21  
416 1 Y 1 S ALA -16  ? E ALA 22  
417 1 Y 1 S ILE -15  ? E ILE 23  
418 1 Y 1 S VAL -14  ? E VAL 24  
419 1 Y 1 S LEU -13  ? E LEU 25  
420 1 Y 1 S TYR -12  ? E TYR 26  
421 1 Y 1 S VAL -11  ? E VAL 27  
422 1 Y 1 S LEU -10  ? E LEU 28  
423 1 Y 1 S LEU -9   ? E LEU 29  
424 1 Y 1 S ALA -8   ? E ALA 30  
425 1 Y 1 S ALA -7   ? E ALA 31  
426 1 Y 1 S ALA -6   ? E ALA 32  
427 1 Y 1 S ALA -5   ? E ALA 33  
428 1 Y 1 S HIS -4   ? E HIS 34  
429 1 Y 1 S SER -3   ? E SER 35  
430 1 Y 1 S ALA -2   ? E ALA 36  
431 1 Y 1 S PHE -1   ? E PHE 37  
432 1 Y 1 S ALA 0    ? E ALA 38  
433 1 Y 1 S SER 121  ? E SER 159 
434 1 Y 1 S GLY 122  ? E GLY 160 
435 1 Y 1 S GLY 123  ? E GLY 161 
436 1 Y 1 S GLY 124  ? E GLY 162 
437 1 Y 1 S GLY 125  ? E GLY 163 
438 1 Y 1 S SER 126  ? E SER 164 
439 1 Y 1 S GLY 127  ? E GLY 165 
440 1 Y 1 S GLY 128  ? E GLY 166 
441 1 Y 1 S GLY 129  ? E GLY 167 
442 1 Y 1 S GLY 130  ? E GLY 168 
443 1 Y 1 S SER 131  ? E SER 169 
444 1 Y 1 S GLY 132  ? E GLY 170 
445 1 Y 1 S GLY 133  ? E GLY 171 
446 1 Y 1 S GLY 134  ? E GLY 172 
447 1 Y 1 S LYS 248  ? E LYS 286 
448 1 Y 1 S ALA 249  ? E ALA 287 
449 1 Y 1 S ALA 250  ? E ALA 288 
450 1 Y 1 S ALA 251  ? E ALA 289 
451 1 Y 1 S HIS 252  ? E HIS 290 
452 1 Y 1 S HIS 253  ? E HIS 291 
453 1 Y 1 S HIS 254  ? E HIS 292 
454 1 Y 1 S HIS 255  ? E HIS 293 
455 1 Y 1 S HIS 256  ? E HIS 294 
456 1 Y 1 S HIS 257  ? E HIS 295 
457 1 Y 1 S HIS 258  ? E HIS 296 
458 1 Y 1 S HIS 259  ? E HIS 297 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
HIS N      N N N 137 
HIS CA     C N S 138 
HIS C      C N N 139 
HIS O      O N N 140 
HIS CB     C N N 141 
HIS CG     C Y N 142 
HIS ND1    N Y N 143 
HIS CD2    C Y N 144 
HIS CE1    C Y N 145 
HIS NE2    N Y N 146 
HIS OXT    O N N 147 
HIS H      H N N 148 
HIS H2     H N N 149 
HIS HA     H N N 150 
HIS HB2    H N N 151 
HIS HB3    H N N 152 
HIS HD1    H N N 153 
HIS HD2    H N N 154 
HIS HE1    H N N 155 
HIS HE2    H N N 156 
HIS HXT    H N N 157 
ILE N      N N N 158 
ILE CA     C N S 159 
ILE C      C N N 160 
ILE O      O N N 161 
ILE CB     C N S 162 
ILE CG1    C N N 163 
ILE CG2    C N N 164 
ILE CD1    C N N 165 
ILE OXT    O N N 166 
ILE H      H N N 167 
ILE H2     H N N 168 
ILE HA     H N N 169 
ILE HB     H N N 170 
ILE HG12   H N N 171 
ILE HG13   H N N 172 
ILE HG21   H N N 173 
ILE HG22   H N N 174 
ILE HG23   H N N 175 
ILE HD11   H N N 176 
ILE HD12   H N N 177 
ILE HD13   H N N 178 
ILE HXT    H N N 179 
LEU N      N N N 180 
LEU CA     C N S 181 
LEU C      C N N 182 
LEU O      O N N 183 
LEU CB     C N N 184 
LEU CG     C N N 185 
LEU CD1    C N N 186 
LEU CD2    C N N 187 
LEU OXT    O N N 188 
LEU H      H N N 189 
LEU H2     H N N 190 
LEU HA     H N N 191 
LEU HB2    H N N 192 
LEU HB3    H N N 193 
LEU HG     H N N 194 
LEU HD11   H N N 195 
LEU HD12   H N N 196 
LEU HD13   H N N 197 
LEU HD21   H N N 198 
LEU HD22   H N N 199 
LEU HD23   H N N 200 
LEU HXT    H N N 201 
LYS N      N N N 202 
LYS CA     C N S 203 
LYS C      C N N 204 
LYS O      O N N 205 
LYS CB     C N N 206 
LYS CG     C N N 207 
LYS CD     C N N 208 
LYS CE     C N N 209 
LYS NZ     N N N 210 
LYS OXT    O N N 211 
LYS H      H N N 212 
LYS H2     H N N 213 
LYS HA     H N N 214 
LYS HB2    H N N 215 
LYS HB3    H N N 216 
LYS HG2    H N N 217 
LYS HG3    H N N 218 
LYS HD2    H N N 219 
LYS HD3    H N N 220 
LYS HE2    H N N 221 
LYS HE3    H N N 222 
LYS HZ1    H N N 223 
LYS HZ2    H N N 224 
LYS HZ3    H N N 225 
LYS HXT    H N N 226 
MET N      N N N 227 
MET CA     C N S 228 
MET C      C N N 229 
MET O      O N N 230 
MET CB     C N N 231 
MET CG     C N N 232 
MET SD     S N N 233 
MET CE     C N N 234 
MET OXT    O N N 235 
MET H      H N N 236 
MET H2     H N N 237 
MET HA     H N N 238 
MET HB2    H N N 239 
MET HB3    H N N 240 
MET HG2    H N N 241 
MET HG3    H N N 242 
MET HE1    H N N 243 
MET HE2    H N N 244 
MET HE3    H N N 245 
MET HXT    H N N 246 
PHE N      N N N 247 
PHE CA     C N S 248 
PHE C      C N N 249 
PHE O      O N N 250 
PHE CB     C N N 251 
PHE CG     C Y N 252 
PHE CD1    C Y N 253 
PHE CD2    C Y N 254 
PHE CE1    C Y N 255 
PHE CE2    C Y N 256 
PHE CZ     C Y N 257 
PHE OXT    O N N 258 
PHE H      H N N 259 
PHE H2     H N N 260 
PHE HA     H N N 261 
PHE HB2    H N N 262 
PHE HB3    H N N 263 
PHE HD1    H N N 264 
PHE HD2    H N N 265 
PHE HE1    H N N 266 
PHE HE2    H N N 267 
PHE HZ     H N N 268 
PHE HXT    H N N 269 
PRO N      N N N 270 
PRO CA     C N S 271 
PRO C      C N N 272 
PRO O      O N N 273 
PRO CB     C N N 274 
PRO CG     C N N 275 
PRO CD     C N N 276 
PRO OXT    O N N 277 
PRO H      H N N 278 
PRO HA     H N N 279 
PRO HB2    H N N 280 
PRO HB3    H N N 281 
PRO HG2    H N N 282 
PRO HG3    H N N 283 
PRO HD2    H N N 284 
PRO HD3    H N N 285 
PRO HXT    H N N 286 
SER N      N N N 287 
SER CA     C N S 288 
SER C      C N N 289 
SER O      O N N 290 
SER CB     C N N 291 
SER OG     O N N 292 
SER OXT    O N N 293 
SER H      H N N 294 
SER H2     H N N 295 
SER HA     H N N 296 
SER HB2    H N N 297 
SER HB3    H N N 298 
SER HG     H N N 299 
SER HXT    H N N 300 
THR N      N N N 301 
THR CA     C N S 302 
THR C      C N N 303 
THR O      O N N 304 
THR CB     C N R 305 
THR OG1    O N N 306 
THR CG2    C N N 307 
THR OXT    O N N 308 
THR H      H N N 309 
THR H2     H N N 310 
THR HA     H N N 311 
THR HB     H N N 312 
THR HG1    H N N 313 
THR HG21   H N N 314 
THR HG22   H N N 315 
THR HG23   H N N 316 
THR HXT    H N N 317 
TRP N      N N N 318 
TRP CA     C N S 319 
TRP C      C N N 320 
TRP O      O N N 321 
TRP CB     C N N 322 
TRP CG     C Y N 323 
TRP CD1    C Y N 324 
TRP CD2    C Y N 325 
TRP NE1    N Y N 326 
TRP CE2    C Y N 327 
TRP CE3    C Y N 328 
TRP CZ2    C Y N 329 
TRP CZ3    C Y N 330 
TRP CH2    C Y N 331 
TRP OXT    O N N 332 
TRP H      H N N 333 
TRP H2     H N N 334 
TRP HA     H N N 335 
TRP HB2    H N N 336 
TRP HB3    H N N 337 
TRP HD1    H N N 338 
TRP HE1    H N N 339 
TRP HE3    H N N 340 
TRP HZ2    H N N 341 
TRP HZ3    H N N 342 
TRP HH2    H N N 343 
TRP HXT    H N N 344 
TYR N      N N N 345 
TYR CA     C N S 346 
TYR C      C N N 347 
TYR O      O N N 348 
TYR CB     C N N 349 
TYR CG     C Y N 350 
TYR CD1    C Y N 351 
TYR CD2    C Y N 352 
TYR CE1    C Y N 353 
TYR CE2    C Y N 354 
TYR CZ     C Y N 355 
TYR OH     O N N 356 
TYR OXT    O N N 357 
TYR H      H N N 358 
TYR H2     H N N 359 
TYR HA     H N N 360 
TYR HB2    H N N 361 
TYR HB3    H N N 362 
TYR HD1    H N N 363 
TYR HD2    H N N 364 
TYR HE1    H N N 365 
TYR HE2    H N N 366 
TYR HH     H N N 367 
TYR HXT    H N N 368 
UGA "C1'"  C N R 369 
UGA "C2'"  C N R 370 
UGA "O2'"  O N N 371 
UGA "C3'"  C N S 372 
UGA "O3'"  O N N 373 
UGA "C4'"  C N S 374 
UGA "O4'"  O N N 375 
UGA "C5'"  C N S 376 
UGA "O5'"  O N N 377 
UGA "C6'"  C N N 378 
UGA "O'P"  O N N 379 
UGA "O'Q"  O N N 380 
UGA PB     P N S 381 
UGA O1B    O N N 382 
UGA O2B    O N N 383 
UGA O3B    O N N 384 
UGA O3A    O N N 385 
UGA PA     P N R 386 
UGA O1A    O N N 387 
UGA O2A    O N N 388 
UGA O5D    O N N 389 
UGA C5D    C N N 390 
UGA C4D    C N R 391 
UGA O4D    O N N 392 
UGA C3D    C N S 393 
UGA O3D    O N N 394 
UGA C2D    C N R 395 
UGA O2D    O N N 396 
UGA C1D    C N R 397 
UGA N1     N Y N 398 
UGA C6     C Y N 399 
UGA C2     C Y N 400 
UGA O2     O N N 401 
UGA N3     N Y N 402 
UGA C4     C Y N 403 
UGA O4     O N N 404 
UGA C5     C Y N 405 
UGA "H1'1" H N N 406 
UGA "H2'1" H N N 407 
UGA "HO'2" H N N 408 
UGA "H3'1" H N N 409 
UGA "HO'3" H N N 410 
UGA "H4'1" H N N 411 
UGA "HO'4" H N N 412 
UGA "H5'1" H N N 413 
UGA "HO'6" H N N 414 
UGA HOB2   H N N 415 
UGA HOA2   H N N 416 
UGA H5A1   H N N 417 
UGA "H5'2" H N N 418 
UGA H4A1   H N N 419 
UGA H3A1   H N N 420 
UGA HOA3   H N N 421 
UGA H2A1   H N N 422 
UGA HOC2   H N N 423 
UGA H1A1   H N N 424 
UGA H61    H N N 425 
UGA HN3    H N N 426 
UGA H51    H N N 427 
VAL N      N N N 428 
VAL CA     C N S 429 
VAL C      C N N 430 
VAL O      O N N 431 
VAL CB     C N N 432 
VAL CG1    C N N 433 
VAL CG2    C N N 434 
VAL OXT    O N N 435 
VAL H      H N N 436 
VAL H2     H N N 437 
VAL HA     H N N 438 
VAL HB     H N N 439 
VAL HG11   H N N 440 
VAL HG12   H N N 441 
VAL HG13   H N N 442 
VAL HG21   H N N 443 
VAL HG22   H N N 444 
VAL HG23   H N N 445 
VAL HXT    H N N 446 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
HIS N     CA     sing N N 129 
HIS N     H      sing N N 130 
HIS N     H2     sing N N 131 
HIS CA    C      sing N N 132 
HIS CA    CB     sing N N 133 
HIS CA    HA     sing N N 134 
HIS C     O      doub N N 135 
HIS C     OXT    sing N N 136 
HIS CB    CG     sing N N 137 
HIS CB    HB2    sing N N 138 
HIS CB    HB3    sing N N 139 
HIS CG    ND1    sing Y N 140 
HIS CG    CD2    doub Y N 141 
HIS ND1   CE1    doub Y N 142 
HIS ND1   HD1    sing N N 143 
HIS CD2   NE2    sing Y N 144 
HIS CD2   HD2    sing N N 145 
HIS CE1   NE2    sing Y N 146 
HIS CE1   HE1    sing N N 147 
HIS NE2   HE2    sing N N 148 
HIS OXT   HXT    sing N N 149 
ILE N     CA     sing N N 150 
ILE N     H      sing N N 151 
ILE N     H2     sing N N 152 
ILE CA    C      sing N N 153 
ILE CA    CB     sing N N 154 
ILE CA    HA     sing N N 155 
ILE C     O      doub N N 156 
ILE C     OXT    sing N N 157 
ILE CB    CG1    sing N N 158 
ILE CB    CG2    sing N N 159 
ILE CB    HB     sing N N 160 
ILE CG1   CD1    sing N N 161 
ILE CG1   HG12   sing N N 162 
ILE CG1   HG13   sing N N 163 
ILE CG2   HG21   sing N N 164 
ILE CG2   HG22   sing N N 165 
ILE CG2   HG23   sing N N 166 
ILE CD1   HD11   sing N N 167 
ILE CD1   HD12   sing N N 168 
ILE CD1   HD13   sing N N 169 
ILE OXT   HXT    sing N N 170 
LEU N     CA     sing N N 171 
LEU N     H      sing N N 172 
LEU N     H2     sing N N 173 
LEU CA    C      sing N N 174 
LEU CA    CB     sing N N 175 
LEU CA    HA     sing N N 176 
LEU C     O      doub N N 177 
LEU C     OXT    sing N N 178 
LEU CB    CG     sing N N 179 
LEU CB    HB2    sing N N 180 
LEU CB    HB3    sing N N 181 
LEU CG    CD1    sing N N 182 
LEU CG    CD2    sing N N 183 
LEU CG    HG     sing N N 184 
LEU CD1   HD11   sing N N 185 
LEU CD1   HD12   sing N N 186 
LEU CD1   HD13   sing N N 187 
LEU CD2   HD21   sing N N 188 
LEU CD2   HD22   sing N N 189 
LEU CD2   HD23   sing N N 190 
LEU OXT   HXT    sing N N 191 
LYS N     CA     sing N N 192 
LYS N     H      sing N N 193 
LYS N     H2     sing N N 194 
LYS CA    C      sing N N 195 
LYS CA    CB     sing N N 196 
LYS CA    HA     sing N N 197 
LYS C     O      doub N N 198 
LYS C     OXT    sing N N 199 
LYS CB    CG     sing N N 200 
LYS CB    HB2    sing N N 201 
LYS CB    HB3    sing N N 202 
LYS CG    CD     sing N N 203 
LYS CG    HG2    sing N N 204 
LYS CG    HG3    sing N N 205 
LYS CD    CE     sing N N 206 
LYS CD    HD2    sing N N 207 
LYS CD    HD3    sing N N 208 
LYS CE    NZ     sing N N 209 
LYS CE    HE2    sing N N 210 
LYS CE    HE3    sing N N 211 
LYS NZ    HZ1    sing N N 212 
LYS NZ    HZ2    sing N N 213 
LYS NZ    HZ3    sing N N 214 
LYS OXT   HXT    sing N N 215 
MET N     CA     sing N N 216 
MET N     H      sing N N 217 
MET N     H2     sing N N 218 
MET CA    C      sing N N 219 
MET CA    CB     sing N N 220 
MET CA    HA     sing N N 221 
MET C     O      doub N N 222 
MET C     OXT    sing N N 223 
MET CB    CG     sing N N 224 
MET CB    HB2    sing N N 225 
MET CB    HB3    sing N N 226 
MET CG    SD     sing N N 227 
MET CG    HG2    sing N N 228 
MET CG    HG3    sing N N 229 
MET SD    CE     sing N N 230 
MET CE    HE1    sing N N 231 
MET CE    HE2    sing N N 232 
MET CE    HE3    sing N N 233 
MET OXT   HXT    sing N N 234 
PHE N     CA     sing N N 235 
PHE N     H      sing N N 236 
PHE N     H2     sing N N 237 
PHE CA    C      sing N N 238 
PHE CA    CB     sing N N 239 
PHE CA    HA     sing N N 240 
PHE C     O      doub N N 241 
PHE C     OXT    sing N N 242 
PHE CB    CG     sing N N 243 
PHE CB    HB2    sing N N 244 
PHE CB    HB3    sing N N 245 
PHE CG    CD1    doub Y N 246 
PHE CG    CD2    sing Y N 247 
PHE CD1   CE1    sing Y N 248 
PHE CD1   HD1    sing N N 249 
PHE CD2   CE2    doub Y N 250 
PHE CD2   HD2    sing N N 251 
PHE CE1   CZ     doub Y N 252 
PHE CE1   HE1    sing N N 253 
PHE CE2   CZ     sing Y N 254 
PHE CE2   HE2    sing N N 255 
PHE CZ    HZ     sing N N 256 
PHE OXT   HXT    sing N N 257 
PRO N     CA     sing N N 258 
PRO N     CD     sing N N 259 
PRO N     H      sing N N 260 
PRO CA    C      sing N N 261 
PRO CA    CB     sing N N 262 
PRO CA    HA     sing N N 263 
PRO C     O      doub N N 264 
PRO C     OXT    sing N N 265 
PRO CB    CG     sing N N 266 
PRO CB    HB2    sing N N 267 
PRO CB    HB3    sing N N 268 
PRO CG    CD     sing N N 269 
PRO CG    HG2    sing N N 270 
PRO CG    HG3    sing N N 271 
PRO CD    HD2    sing N N 272 
PRO CD    HD3    sing N N 273 
PRO OXT   HXT    sing N N 274 
SER N     CA     sing N N 275 
SER N     H      sing N N 276 
SER N     H2     sing N N 277 
SER CA    C      sing N N 278 
SER CA    CB     sing N N 279 
SER CA    HA     sing N N 280 
SER C     O      doub N N 281 
SER C     OXT    sing N N 282 
SER CB    OG     sing N N 283 
SER CB    HB2    sing N N 284 
SER CB    HB3    sing N N 285 
SER OG    HG     sing N N 286 
SER OXT   HXT    sing N N 287 
THR N     CA     sing N N 288 
THR N     H      sing N N 289 
THR N     H2     sing N N 290 
THR CA    C      sing N N 291 
THR CA    CB     sing N N 292 
THR CA    HA     sing N N 293 
THR C     O      doub N N 294 
THR C     OXT    sing N N 295 
THR CB    OG1    sing N N 296 
THR CB    CG2    sing N N 297 
THR CB    HB     sing N N 298 
THR OG1   HG1    sing N N 299 
THR CG2   HG21   sing N N 300 
THR CG2   HG22   sing N N 301 
THR CG2   HG23   sing N N 302 
THR OXT   HXT    sing N N 303 
TRP N     CA     sing N N 304 
TRP N     H      sing N N 305 
TRP N     H2     sing N N 306 
TRP CA    C      sing N N 307 
TRP CA    CB     sing N N 308 
TRP CA    HA     sing N N 309 
TRP C     O      doub N N 310 
TRP C     OXT    sing N N 311 
TRP CB    CG     sing N N 312 
TRP CB    HB2    sing N N 313 
TRP CB    HB3    sing N N 314 
TRP CG    CD1    doub Y N 315 
TRP CG    CD2    sing Y N 316 
TRP CD1   NE1    sing Y N 317 
TRP CD1   HD1    sing N N 318 
TRP CD2   CE2    doub Y N 319 
TRP CD2   CE3    sing Y N 320 
TRP NE1   CE2    sing Y N 321 
TRP NE1   HE1    sing N N 322 
TRP CE2   CZ2    sing Y N 323 
TRP CE3   CZ3    doub Y N 324 
TRP CE3   HE3    sing N N 325 
TRP CZ2   CH2    doub Y N 326 
TRP CZ2   HZ2    sing N N 327 
TRP CZ3   CH2    sing Y N 328 
TRP CZ3   HZ3    sing N N 329 
TRP CH2   HH2    sing N N 330 
TRP OXT   HXT    sing N N 331 
TYR N     CA     sing N N 332 
TYR N     H      sing N N 333 
TYR N     H2     sing N N 334 
TYR CA    C      sing N N 335 
TYR CA    CB     sing N N 336 
TYR CA    HA     sing N N 337 
TYR C     O      doub N N 338 
TYR C     OXT    sing N N 339 
TYR CB    CG     sing N N 340 
TYR CB    HB2    sing N N 341 
TYR CB    HB3    sing N N 342 
TYR CG    CD1    doub Y N 343 
TYR CG    CD2    sing Y N 344 
TYR CD1   CE1    sing Y N 345 
TYR CD1   HD1    sing N N 346 
TYR CD2   CE2    doub Y N 347 
TYR CD2   HD2    sing N N 348 
TYR CE1   CZ     doub Y N 349 
TYR CE1   HE1    sing N N 350 
TYR CE2   CZ     sing Y N 351 
TYR CE2   HE2    sing N N 352 
TYR CZ    OH     sing N N 353 
TYR OH    HH     sing N N 354 
TYR OXT   HXT    sing N N 355 
UGA "C1'" "C2'"  sing N N 356 
UGA "C1'" "O5'"  sing N N 357 
UGA "C1'" O3B    sing N N 358 
UGA "C1'" "H1'1" sing N N 359 
UGA "C2'" "O2'"  sing N N 360 
UGA "C2'" "C3'"  sing N N 361 
UGA "C2'" "H2'1" sing N N 362 
UGA "O2'" "HO'2" sing N N 363 
UGA "C3'" "O3'"  sing N N 364 
UGA "C3'" "C4'"  sing N N 365 
UGA "C3'" "H3'1" sing N N 366 
UGA "O3'" "HO'3" sing N N 367 
UGA "C4'" "O4'"  sing N N 368 
UGA "C4'" "C5'"  sing N N 369 
UGA "C4'" "H4'1" sing N N 370 
UGA "O4'" "HO'4" sing N N 371 
UGA "C5'" "O5'"  sing N N 372 
UGA "C5'" "C6'"  sing N N 373 
UGA "C5'" "H5'1" sing N N 374 
UGA "C6'" "O'P"  doub N N 375 
UGA "C6'" "O'Q"  sing N N 376 
UGA "O'Q" "HO'6" sing N N 377 
UGA PB    O1B    doub N N 378 
UGA PB    O2B    sing N N 379 
UGA PB    O3B    sing N N 380 
UGA PB    O3A    sing N N 381 
UGA O2B   HOB2   sing N N 382 
UGA O3A   PA     sing N N 383 
UGA PA    O1A    doub N N 384 
UGA PA    O2A    sing N N 385 
UGA PA    O5D    sing N N 386 
UGA O2A   HOA2   sing N N 387 
UGA O5D   C5D    sing N N 388 
UGA C5D   C4D    sing N N 389 
UGA C5D   H5A1   sing N N 390 
UGA C5D   "H5'2" sing N N 391 
UGA C4D   O4D    sing N N 392 
UGA C4D   C3D    sing N N 393 
UGA C4D   H4A1   sing N N 394 
UGA O4D   C1D    sing N N 395 
UGA C3D   O3D    sing N N 396 
UGA C3D   C2D    sing N N 397 
UGA C3D   H3A1   sing N N 398 
UGA O3D   HOA3   sing N N 399 
UGA C2D   O2D    sing N N 400 
UGA C2D   C1D    sing N N 401 
UGA C2D   H2A1   sing N N 402 
UGA O2D   HOC2   sing N N 403 
UGA C1D   N1     sing N N 404 
UGA C1D   H1A1   sing N N 405 
UGA N1    C6     sing Y N 406 
UGA N1    C2     sing Y N 407 
UGA C6    C5     doub Y N 408 
UGA C6    H61    sing N N 409 
UGA C2    O2     doub N N 410 
UGA C2    N3     sing Y N 411 
UGA N3    C4     sing Y N 412 
UGA N3    HN3    sing N N 413 
UGA C4    O4     doub N N 414 
UGA C4    C5     sing Y N 415 
UGA C5    H51    sing N N 416 
VAL N     CA     sing N N 417 
VAL N     H      sing N N 418 
VAL N     H2     sing N N 419 
VAL CA    C      sing N N 420 
VAL CA    CB     sing N N 421 
VAL CA    HA     sing N N 422 
VAL C     O      doub N N 423 
VAL C     OXT    sing N N 424 
VAL CB    CG1    sing N N 425 
VAL CB    CG2    sing N N 426 
VAL CB    HB     sing N N 427 
VAL CG1   HG11   sing N N 428 
VAL CG1   HG12   sing N N 429 
VAL CG1   HG13   sing N N 430 
VAL CG2   HG21   sing N N 431 
VAL CG2   HG22   sing N N 432 
VAL CG2   HG23   sing N N 433 
VAL OXT   HXT    sing N N 434 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-02 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9J0I 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              'UDP-Glucuronic acid bound purinergic receptor P2Y14 complex with Gi' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 1 9606 'Homo sapiens'     ? ? ? ? ? 
? ? 1 2 562  'Escherichia coli' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   1 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60.00 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   NO 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9J0I 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . CYS A 1 3   ? 127.512 107.651 127.334 1.00 43.42  ? 3   CYS A N     1 
ATOM   2    C CA    . CYS A 1 3   ? 126.101 107.743 127.689 1.00 46.87  ? 3   CYS A CA    1 
ATOM   3    C C     . CYS A 1 3   ? 125.306 108.439 126.589 1.00 44.95  ? 3   CYS A C     1 
ATOM   4    O O     . CYS A 1 3   ? 125.443 109.646 126.385 1.00 43.92  ? 3   CYS A O     1 
ATOM   5    C CB    . CYS A 1 3   ? 125.928 108.485 129.016 1.00 46.57  ? 3   CYS A CB    1 
ATOM   6    S SG    . CYS A 1 3   ? 124.305 108.276 129.784 1.00 51.67  ? 3   CYS A SG    1 
ATOM   7    N N     . THR A 1 4   ? 124.480 107.662 125.885 1.00 37.19  ? 4   THR A N     1 
ATOM   8    C CA    . THR A 1 4   ? 123.639 108.159 124.793 1.00 36.52  ? 4   THR A CA    1 
ATOM   9    C C     . THR A 1 4   ? 124.464 108.842 123.705 1.00 37.10  ? 4   THR A C     1 
ATOM   10   O O     . THR A 1 4   ? 123.985 109.757 123.030 1.00 37.55  ? 4   THR A O     1 
ATOM   11   C CB    . THR A 1 4   ? 122.548 109.105 125.306 1.00 36.99  ? 4   THR A CB    1 
ATOM   12   O OG1   . THR A 1 4   ? 123.129 110.366 125.659 1.00 36.07  ? 4   THR A OG1   1 
ATOM   13   C CG2   . THR A 1 4   ? 121.852 108.511 126.522 1.00 37.52  ? 4   THR A CG2   1 
ATOM   14   N N     . LEU A 1 5   ? 125.709 108.406 123.528 1.00 25.37  ? 5   LEU A N     1 
ATOM   15   C CA    . LEU A 1 5   ? 126.589 108.946 122.503 1.00 20.86  ? 5   LEU A CA    1 
ATOM   16   C C     . LEU A 1 5   ? 127.372 107.810 121.866 1.00 21.29  ? 5   LEU A C     1 
ATOM   17   O O     . LEU A 1 5   ? 127.827 106.896 122.558 1.00 26.38  ? 5   LEU A O     1 
ATOM   18   C CB    . LEU A 1 5   ? 127.558 109.987 123.079 1.00 20.11  ? 5   LEU A CB    1 
ATOM   19   C CG    . LEU A 1 5   ? 127.021 111.404 123.280 1.00 22.72  ? 5   LEU A CG    1 
ATOM   20   C CD1   . LEU A 1 5   ? 128.120 112.320 123.792 1.00 19.50  ? 5   LEU A CD1   1 
ATOM   21   C CD2   . LEU A 1 5   ? 126.429 111.943 121.989 1.00 22.29  ? 5   LEU A CD2   1 
ATOM   22   N N     . SER A 1 6   ? 127.526 107.875 120.548 1.00 15.23  ? 6   SER A N     1 
ATOM   23   C CA    . SER A 1 6   ? 128.315 106.887 119.834 1.00 5.24   ? 6   SER A CA    1 
ATOM   24   C C     . SER A 1 6   ? 129.805 107.165 120.019 1.00 5.14   ? 6   SER A C     1 
ATOM   25   O O     . SER A 1 6   ? 130.214 108.212 120.526 1.00 6.80   ? 6   SER A O     1 
ATOM   26   C CB    . SER A 1 6   ? 127.948 106.878 118.352 1.00 4.71   ? 6   SER A CB    1 
ATOM   27   O OG    . SER A 1 6   ? 128.128 108.158 117.774 1.00 12.57  ? 6   SER A OG    1 
ATOM   28   N N     . ALA A 1 7   ? 130.625 106.196 119.603 1.00 6.68   ? 7   ALA A N     1 
ATOM   29   C CA    . ALA A 1 7   ? 132.072 106.355 119.712 1.00 4.04   ? 7   ALA A CA    1 
ATOM   30   C C     . ALA A 1 7   ? 132.558 107.538 118.886 1.00 5.08   ? 7   ALA A C     1 
ATOM   31   O O     . ALA A 1 7   ? 133.408 108.316 119.337 1.00 12.35  ? 7   ALA A O     1 
ATOM   32   C CB    . ALA A 1 7   ? 132.774 105.069 119.279 1.00 1.64   ? 7   ALA A CB    1 
ATOM   33   N N     . GLU A 1 8   ? 132.027 107.689 117.671 1.00 3.79   ? 8   GLU A N     1 
ATOM   34   C CA    . GLU A 1 8   ? 132.382 108.836 116.843 1.00 0.00   ? 8   GLU A CA    1 
ATOM   35   C C     . GLU A 1 8   ? 131.913 110.139 117.477 1.00 2.28   ? 8   GLU A C     1 
ATOM   36   O O     . GLU A 1 8   ? 132.623 111.149 117.433 1.00 13.12  ? 8   GLU A O     1 
ATOM   37   C CB    . GLU A 1 8   ? 131.792 108.669 115.446 1.00 2.91   ? 8   GLU A CB    1 
ATOM   38   C CG    . GLU A 1 8   ? 132.168 107.358 114.788 1.00 3.14   ? 8   GLU A CG    1 
ATOM   39   C CD    . GLU A 1 8   ? 132.269 107.472 113.286 1.00 4.26   ? 8   GLU A CD    1 
ATOM   40   O OE1   . GLU A 1 8   ? 132.467 108.597 112.785 1.00 9.03   ? 8   GLU A OE1   1 
ATOM   41   O OE2   . GLU A 1 8   ? 132.152 106.434 112.605 1.00 3.91   ? 8   GLU A OE2   1 
ATOM   42   N N     . ASP A 1 9   ? 130.718 110.135 118.072 1.00 0.00   ? 9   ASP A N     1 
ATOM   43   C CA    . ASP A 1 9   ? 130.238 111.323 118.771 1.00 0.35   ? 9   ASP A CA    1 
ATOM   44   C C     . ASP A 1 9   ? 131.117 111.649 119.972 1.00 6.14   ? 9   ASP A C     1 
ATOM   45   O O     . ASP A 1 9   ? 131.417 112.820 120.231 1.00 11.88  ? 9   ASP A O     1 
ATOM   46   C CB    . ASP A 1 9   ? 128.786 111.125 119.203 1.00 5.28   ? 9   ASP A CB    1 
ATOM   47   N N     . LYS A 1 10  ? 131.539 110.625 120.718 1.00 5.37   ? 10  LYS A N     1 
ATOM   48   C CA    . LYS A 1 10  ? 132.428 110.853 121.854 1.00 3.50   ? 10  LYS A CA    1 
ATOM   49   C C     . LYS A 1 10  ? 133.761 111.436 121.403 1.00 5.12   ? 10  LYS A C     1 
ATOM   50   O O     . LYS A 1 10  ? 134.296 112.352 122.038 1.00 8.45   ? 10  LYS A O     1 
ATOM   51   C CB    . LYS A 1 10  ? 132.648 109.549 122.619 1.00 9.36   ? 10  LYS A CB    1 
ATOM   52   C CG    . LYS A 1 10  ? 131.435 109.063 123.391 1.00 10.51  ? 10  LYS A CG    1 
ATOM   53   C CD    . LYS A 1 10  ? 131.732 107.758 124.109 1.00 7.34   ? 10  LYS A CD    1 
ATOM   54   C CE    . LYS A 1 10  ? 130.503 107.231 124.829 1.00 14.36  ? 10  LYS A CE    1 
ATOM   55   N NZ    . LYS A 1 10  ? 130.776 105.939 125.517 1.00 15.35  ? 10  LYS A NZ    1 
ATOM   56   N N     . ALA A 1 11  ? 134.315 110.918 120.305 1.00 3.38   ? 11  ALA A N     1 
ATOM   57   C CA    . ALA A 1 11  ? 135.577 111.450 119.804 1.00 3.02   ? 11  ALA A CA    1 
ATOM   58   C C     . ALA A 1 11  ? 135.418 112.868 119.264 1.00 6.21   ? 11  ALA A C     1 
ATOM   59   O O     . ALA A 1 11  ? 136.333 113.687 119.399 1.00 12.27  ? 11  ALA A O     1 
ATOM   60   C CB    . ALA A 1 11  ? 136.147 110.522 118.735 1.00 5.31   ? 11  ALA A CB    1 
ATOM   61   N N     . ALA A 1 12  ? 134.269 113.179 118.658 1.00 4.55   ? 12  ALA A N     1 
ATOM   62   C CA    . ALA A 1 12  ? 134.005 114.551 118.237 1.00 0.00   ? 12  ALA A CA    1 
ATOM   63   C C     . ALA A 1 12  ? 133.907 115.485 119.437 1.00 4.54   ? 12  ALA A C     1 
ATOM   64   O O     . ALA A 1 12  ? 134.378 116.626 119.387 1.00 18.85  ? 12  ALA A O     1 
ATOM   65   C CB    . ALA A 1 12  ? 132.725 114.608 117.404 1.00 2.29   ? 12  ALA A CB    1 
ATOM   66   N N     . VAL A 1 13  ? 133.291 115.018 120.525 1.00 11.38  ? 13  VAL A N     1 
ATOM   67   C CA    . VAL A 1 13  ? 133.234 115.812 121.750 1.00 6.86   ? 13  VAL A CA    1 
ATOM   68   C C     . VAL A 1 13  ? 134.636 116.030 122.307 1.00 3.81   ? 13  VAL A C     1 
ATOM   69   O O     . VAL A 1 13  ? 134.963 117.117 122.798 1.00 6.68   ? 13  VAL A O     1 
ATOM   70   C CB    . VAL A 1 13  ? 132.307 115.137 122.780 1.00 2.22   ? 13  VAL A CB    1 
ATOM   71   C CG1   . VAL A 1 13  ? 132.473 115.771 124.151 1.00 9.13   ? 13  VAL A CG1   1 
ATOM   72   C CG2   . VAL A 1 13  ? 130.859 115.226 122.325 1.00 1.82   ? 13  VAL A CG2   1 
ATOM   73   N N     . GLU A 1 14  ? 135.483 115.001 122.244 1.00 5.46   ? 14  GLU A N     1 
ATOM   74   C CA    . GLU A 1 14  ? 136.868 115.150 122.685 1.00 7.10   ? 14  GLU A CA    1 
ATOM   75   C C     . GLU A 1 14  ? 137.613 116.173 121.835 1.00 10.79  ? 14  GLU A C     1 
ATOM   76   O O     . GLU A 1 14  ? 138.389 116.984 122.356 1.00 14.69  ? 14  GLU A O     1 
ATOM   77   C CB    . GLU A 1 14  ? 137.580 113.799 122.637 1.00 5.15   ? 14  GLU A CB    1 
ATOM   78   C CG    . GLU A 1 14  ? 137.121 112.813 123.694 1.00 7.71   ? 14  GLU A CG    1 
ATOM   79   C CD    . GLU A 1 14  ? 137.577 111.398 123.402 1.00 17.86  ? 14  GLU A CD    1 
ATOM   80   O OE1   . GLU A 1 14  ? 138.770 111.212 123.083 1.00 19.13  ? 14  GLU A OE1   1 
ATOM   81   O OE2   . GLU A 1 14  ? 136.744 110.472 123.492 1.00 17.82  ? 14  GLU A OE2   1 
ATOM   82   N N     . ARG A 1 15  ? 137.394 116.142 120.519 1.00 9.85   ? 15  ARG A N     1 
ATOM   83   C CA    . ARG A 1 15  ? 138.005 117.131 119.636 1.00 8.74   ? 15  ARG A CA    1 
ATOM   84   C C     . ARG A 1 15  ? 137.523 118.536 119.970 1.00 7.84   ? 15  ARG A C     1 
ATOM   85   O O     . ARG A 1 15  ? 138.313 119.489 119.980 1.00 11.62  ? 15  ARG A O     1 
ATOM   86   C CB    . ARG A 1 15  ? 137.693 116.787 118.179 1.00 11.20  ? 15  ARG A CB    1 
ATOM   87   C CG    . ARG A 1 15  ? 138.138 117.834 117.177 1.00 17.09  ? 15  ARG A CG    1 
ATOM   88   C CD    . ARG A 1 15  ? 137.546 117.563 115.806 1.00 12.58  ? 15  ARG A CD    1 
ATOM   89   N NE    . ARG A 1 15  ? 137.824 118.641 114.866 1.00 11.89  ? 15  ARG A NE    1 
ATOM   90   C CZ    . ARG A 1 15  ? 138.929 118.737 114.141 1.00 10.69  ? 15  ARG A CZ    1 
ATOM   91   N NH1   . ARG A 1 15  ? 139.892 117.834 114.228 1.00 14.81  ? 15  ARG A NH1   1 
ATOM   92   N NH2   . ARG A 1 15  ? 139.073 119.763 113.309 1.00 12.77  ? 15  ARG A NH2   1 
ATOM   93   N N     . SER A 1 16  ? 136.227 118.682 120.250 1.00 7.18   ? 16  SER A N     1 
ATOM   94   C CA    . SER A 1 16  ? 135.689 119.982 120.634 1.00 3.38   ? 16  SER A CA    1 
ATOM   95   C C     . SER A 1 16  ? 136.298 120.466 121.945 1.00 12.26  ? 16  SER A C     1 
ATOM   96   O O     . SER A 1 16  ? 136.583 121.657 122.102 1.00 15.10  ? 16  SER A O     1 
ATOM   97   C CB    . SER A 1 16  ? 134.167 119.906 120.740 1.00 3.45   ? 16  SER A CB    1 
ATOM   98   O OG    . SER A 1 16  ? 133.619 121.150 121.137 1.00 13.87  ? 16  SER A OG    1 
ATOM   99   N N     . LYS A 1 17  ? 136.498 119.556 122.901 1.00 12.39  ? 17  LYS A N     1 
ATOM   100  C CA    . LYS A 1 17  ? 137.127 119.927 124.167 1.00 3.01   ? 17  LYS A CA    1 
ATOM   101  C C     . LYS A 1 17  ? 138.574 120.363 123.964 1.00 7.78   ? 17  LYS A C     1 
ATOM   102  O O     . LYS A 1 17  ? 139.036 121.319 124.599 1.00 12.64  ? 17  LYS A O     1 
ATOM   103  C CB    . LYS A 1 17  ? 137.050 118.762 125.152 1.00 9.52   ? 17  LYS A CB    1 
ATOM   104  C CG    . LYS A 1 17  ? 135.657 118.501 125.697 1.00 11.18  ? 17  LYS A CG    1 
ATOM   105  C CD    . LYS A 1 17  ? 135.668 117.398 126.743 1.00 12.43  ? 17  LYS A CD    1 
ATOM   106  C CE    . LYS A 1 17  ? 135.854 116.033 126.102 1.00 14.25  ? 17  LYS A CE    1 
ATOM   107  N NZ    . LYS A 1 17  ? 135.740 114.926 127.091 1.00 11.88  ? 17  LYS A NZ    1 
ATOM   108  N N     . MET A 1 18  ? 139.309 119.665 123.096 1.00 8.32   ? 18  MET A N     1 
ATOM   109  C CA    . MET A 1 18  ? 140.673 120.086 122.784 1.00 7.09   ? 18  MET A CA    1 
ATOM   110  C C     . MET A 1 18  ? 140.686 121.461 122.130 1.00 9.46   ? 18  MET A C     1 
ATOM   111  O O     . MET A 1 18  ? 141.551 122.295 122.430 1.00 15.67  ? 18  MET A O     1 
ATOM   112  C CB    . MET A 1 18  ? 141.350 119.062 121.877 1.00 12.13  ? 18  MET A CB    1 
ATOM   113  C CG    . MET A 1 18  ? 141.637 117.734 122.541 1.00 14.79  ? 18  MET A CG    1 
ATOM   114  S SD    . MET A 1 18  ? 142.514 116.622 121.434 1.00 33.93  ? 18  MET A SD    1 
ATOM   115  C CE    . MET A 1 18  ? 144.115 117.420 121.360 1.00 14.63  ? 18  MET A CE    1 
ATOM   116  N N     . ILE A 1 19  ? 139.738 121.710 121.225 1.00 10.61  ? 19  ILE A N     1 
ATOM   117  C CA    . ILE A 1 19  ? 139.636 123.023 120.598 1.00 10.49  ? 19  ILE A CA    1 
ATOM   118  C C     . ILE A 1 19  ? 139.330 124.086 121.646 1.00 7.92   ? 19  ILE A C     1 
ATOM   119  O O     . ILE A 1 19  ? 139.876 125.193 121.604 1.00 15.87  ? 19  ILE A O     1 
ATOM   120  C CB    . ILE A 1 19  ? 138.576 122.999 119.480 1.00 10.72  ? 19  ILE A CB    1 
ATOM   121  C CG1   . ILE A 1 19  ? 139.098 122.225 118.270 1.00 7.85   ? 19  ILE A CG1   1 
ATOM   122  C CG2   . ILE A 1 19  ? 138.209 124.406 119.060 1.00 11.22  ? 19  ILE A CG2   1 
ATOM   123  C CD1   . ILE A 1 19  ? 138.023 121.836 117.289 1.00 0.80   ? 19  ILE A CD1   1 
ATOM   124  N N     . ASP A 1 20  ? 138.458 123.765 122.604 1.00 4.29   ? 20  ASP A N     1 
ATOM   125  C CA    . ASP A 1 20  ? 138.157 124.693 123.690 1.00 1.90   ? 20  ASP A CA    1 
ATOM   126  C C     . ASP A 1 20  ? 139.399 125.008 124.514 1.00 6.43   ? 20  ASP A C     1 
ATOM   127  O O     . ASP A 1 20  ? 139.633 126.165 124.879 1.00 14.26  ? 20  ASP A O     1 
ATOM   128  C CB    . ASP A 1 20  ? 137.065 124.111 124.588 1.00 8.75   ? 20  ASP A CB    1 
ATOM   129  C CG    . ASP A 1 20  ? 135.675 124.336 124.038 1.00 13.32  ? 20  ASP A CG    1 
ATOM   130  O OD1   . ASP A 1 20  ? 135.269 125.510 123.924 1.00 15.81  ? 20  ASP A OD1   1 
ATOM   131  O OD2   . ASP A 1 20  ? 134.986 123.343 123.723 1.00 14.34  ? 20  ASP A OD2   1 
ATOM   132  N N     . ARG A 1 21  ? 140.197 123.986 124.831 1.00 10.26  ? 21  ARG A N     1 
ATOM   133  C CA    . ARG A 1 21  ? 141.421 124.219 125.593 1.00 10.16  ? 21  ARG A CA    1 
ATOM   134  C C     . ARG A 1 21  ? 142.395 125.097 124.817 1.00 9.26   ? 21  ARG A C     1 
ATOM   135  O O     . ARG A 1 21  ? 143.008 126.013 125.383 1.00 11.59  ? 21  ARG A O     1 
ATOM   136  C CB    . ARG A 1 21  ? 142.075 122.888 125.962 1.00 10.06  ? 21  ARG A CB    1 
ATOM   137  C CG    . ARG A 1 21  ? 141.327 122.107 127.029 1.00 17.09  ? 21  ARG A CG    1 
ATOM   138  C CD    . ARG A 1 21  ? 142.133 120.910 127.502 1.00 15.97  ? 21  ARG A CD    1 
ATOM   139  N NE    . ARG A 1 21  ? 142.288 119.910 126.453 1.00 14.66  ? 21  ARG A NE    1 
ATOM   140  C CZ    . ARG A 1 21  ? 143.035 118.820 126.562 1.00 17.05  ? 21  ARG A CZ    1 
ATOM   141  N NH1   . ARG A 1 21  ? 143.709 118.552 127.669 1.00 17.19  ? 21  ARG A NH1   1 
ATOM   142  N NH2   . ARG A 1 21  ? 143.107 117.978 125.535 1.00 16.74  ? 21  ARG A NH2   1 
ATOM   143  N N     . ASN A 1 22  ? 142.546 124.836 123.516 1.00 13.78  ? 22  ASN A N     1 
ATOM   144  C CA    . ASN A 1 22  ? 143.422 125.664 122.693 1.00 9.19   ? 22  ASN A CA    1 
ATOM   145  C C     . ASN A 1 22  ? 142.923 127.103 122.628 1.00 12.38  ? 22  ASN A C     1 
ATOM   146  O O     . ASN A 1 22  ? 143.719 128.048 122.681 1.00 13.81  ? 22  ASN A O     1 
ATOM   147  C CB    . ASN A 1 22  ? 143.536 125.070 121.290 1.00 11.03  ? 22  ASN A CB    1 
ATOM   148  C CG    . ASN A 1 22  ? 144.446 123.860 121.242 1.00 16.06  ? 22  ASN A CG    1 
ATOM   149  O OD1   . ASN A 1 22  ? 145.602 123.954 120.829 1.00 18.31  ? 22  ASN A OD1   1 
ATOM   150  N ND2   . ASN A 1 22  ? 143.928 122.713 121.667 1.00 12.14  ? 22  ASN A ND2   1 
ATOM   151  N N     . LEU A 1 23  ? 141.606 127.287 122.510 1.00 13.03  ? 23  LEU A N     1 
ATOM   152  C CA    . LEU A 1 23  ? 141.041 128.632 122.477 1.00 9.78   ? 23  LEU A CA    1 
ATOM   153  C C     . LEU A 1 23  ? 141.268 129.359 123.793 1.00 10.49  ? 23  LEU A C     1 
ATOM   154  O O     . LEU A 1 23  ? 141.576 130.555 123.803 1.00 19.03  ? 23  LEU A O     1 
ATOM   155  C CB    . LEU A 1 23  ? 139.548 128.569 122.158 1.00 7.12   ? 23  LEU A CB    1 
ATOM   156  C CG    . LEU A 1 23  ? 139.175 128.124 120.746 1.00 4.00   ? 23  LEU A CG    1 
ATOM   157  C CD1   . LEU A 1 23  ? 137.681 127.921 120.637 1.00 5.01   ? 23  LEU A CD1   1 
ATOM   158  C CD2   . LEU A 1 23  ? 139.661 129.129 119.726 1.00 10.98  ? 23  LEU A CD2   1 
ATOM   159  N N     . ARG A 1 24  ? 141.106 128.657 124.916 1.00 12.16  ? 24  ARG A N     1 
ATOM   160  C CA    . ARG A 1 24  ? 141.355 129.275 126.213 1.00 8.55   ? 24  ARG A CA    1 
ATOM   161  C C     . ARG A 1 24  ? 142.817 129.676 126.356 1.00 9.51   ? 24  ARG A C     1 
ATOM   162  O O     . ARG A 1 24  ? 143.124 130.760 126.866 1.00 16.15  ? 24  ARG A O     1 
ATOM   163  C CB    . ARG A 1 24  ? 140.946 128.325 127.338 1.00 13.41  ? 24  ARG A CB    1 
ATOM   164  C CG    . ARG A 1 24  ? 139.445 128.179 127.509 1.00 15.10  ? 24  ARG A CG    1 
ATOM   165  C CD    . ARG A 1 24  ? 139.109 126.984 128.385 1.00 16.16  ? 24  ARG A CD    1 
ATOM   166  N NE    . ARG A 1 24  ? 137.719 126.570 128.236 1.00 16.43  ? 24  ARG A NE    1 
ATOM   167  C CZ    . ARG A 1 24  ? 137.324 125.310 128.117 1.00 16.43  ? 24  ARG A CZ    1 
ATOM   168  N NH1   . ARG A 1 24  ? 138.190 124.310 128.128 1.00 15.10  ? 24  ARG A NH1   1 
ATOM   169  N NH2   . ARG A 1 24  ? 136.027 125.047 127.986 1.00 12.65  ? 24  ARG A NH2   1 
ATOM   170  N N     . GLU A 1 25  ? 143.735 128.815 125.908 1.00 11.00  ? 25  GLU A N     1 
ATOM   171  C CA    . GLU A 1 25  ? 145.153 129.159 125.963 1.00 10.07  ? 25  GLU A CA    1 
ATOM   172  C C     . GLU A 1 25  ? 145.462 130.372 125.093 1.00 16.24  ? 25  GLU A C     1 
ATOM   173  O O     . GLU A 1 25  ? 146.200 131.275 125.510 1.00 18.98  ? 25  GLU A O     1 
ATOM   174  C CB    . GLU A 1 25  ? 146.000 127.961 125.535 1.00 11.28  ? 25  GLU A CB    1 
ATOM   175  N N     . ASP A 1 26  ? 144.899 130.415 123.882 1.00 17.70  ? 26  ASP A N     1 
ATOM   176  C CA    . ASP A 1 26  ? 145.127 131.551 122.996 1.00 13.57  ? 26  ASP A CA    1 
ATOM   177  C C     . ASP A 1 26  ? 144.563 132.837 123.587 1.00 13.21  ? 26  ASP A C     1 
ATOM   178  O O     . ASP A 1 26  ? 145.190 133.898 123.496 1.00 17.33  ? 26  ASP A O     1 
ATOM   179  C CB    . ASP A 1 26  ? 144.513 131.277 121.623 1.00 15.45  ? 26  ASP A CB    1 
ATOM   180  C CG    . ASP A 1 26  ? 145.402 130.417 120.749 1.00 21.40  ? 26  ASP A CG    1 
ATOM   181  O OD1   . ASP A 1 26  ? 146.486 130.011 121.218 1.00 22.78  ? 26  ASP A OD1   1 
ATOM   182  O OD2   . ASP A 1 26  ? 145.018 130.149 119.591 1.00 19.40  ? 26  ASP A OD2   1 
ATOM   183  N N     . GLY A 1 27  ? 143.376 132.762 124.190 1.00 10.94  ? 27  GLY A N     1 
ATOM   184  C CA    . GLY A 1 27  ? 142.794 133.942 124.806 1.00 13.08  ? 27  GLY A CA    1 
ATOM   185  C C     . GLY A 1 27  ? 143.584 134.425 126.006 1.00 15.86  ? 27  GLY A C     1 
ATOM   186  O O     . GLY A 1 27  ? 143.723 135.631 126.222 1.00 18.33  ? 27  GLY A O     1 
ATOM   187  N N     . GLU A 1 28  ? 144.103 133.494 126.809 1.00 20.58  ? 28  GLU A N     1 
ATOM   188  C CA    . GLU A 1 28  ? 144.957 133.880 127.927 1.00 20.36  ? 28  GLU A CA    1 
ATOM   189  C C     . GLU A 1 28  ? 146.237 134.542 127.433 1.00 18.89  ? 28  GLU A C     1 
ATOM   190  O O     . GLU A 1 28  ? 146.700 135.529 128.017 1.00 20.65  ? 28  GLU A O     1 
ATOM   191  C CB    . GLU A 1 28  ? 145.278 132.660 128.790 1.00 17.26  ? 28  GLU A CB    1 
ATOM   192  N N     . LYS A 1 29  ? 146.826 134.009 126.360 1.00 18.22  ? 29  LYS A N     1 
ATOM   193  C CA    . LYS A 1 29  ? 148.029 134.619 125.801 1.00 18.23  ? 29  LYS A CA    1 
ATOM   194  C C     . LYS A 1 29  ? 147.742 136.010 125.246 1.00 19.24  ? 29  LYS A C     1 
ATOM   195  O O     . LYS A 1 29  ? 148.545 136.934 125.419 1.00 21.49  ? 29  LYS A O     1 
ATOM   196  C CB    . LYS A 1 29  ? 148.617 133.719 124.714 1.00 16.46  ? 29  LYS A CB    1 
ATOM   197  N N     . ALA A 1 30  ? 146.601 136.178 124.573 1.00 18.73  ? 30  ALA A N     1 
ATOM   198  C CA    . ALA A 1 30  ? 146.271 137.461 123.963 1.00 16.40  ? 30  ALA A CA    1 
ATOM   199  C C     . ALA A 1 30  ? 145.832 138.499 124.988 1.00 17.86  ? 30  ALA A C     1 
ATOM   200  O O     . ALA A 1 30  ? 145.993 139.701 124.751 1.00 21.29  ? 30  ALA A O     1 
ATOM   201  C CB    . ALA A 1 30  ? 145.179 137.276 122.909 1.00 15.88  ? 30  ALA A CB    1 
ATOM   202  N N     . ALA A 1 31  ? 145.271 138.064 126.119 1.00 20.11  ? 31  ALA A N     1 
ATOM   203  C CA    . ALA A 1 31  ? 144.825 139.010 127.136 1.00 21.76  ? 31  ALA A CA    1 
ATOM   204  C C     . ALA A 1 31  ? 145.994 139.752 127.768 1.00 21.00  ? 31  ALA A C     1 
ATOM   205  O O     . ALA A 1 31  ? 145.840 140.904 128.189 1.00 20.99  ? 31  ALA A O     1 
ATOM   206  C CB    . ALA A 1 31  ? 144.014 138.285 128.210 1.00 21.24  ? 31  ALA A CB    1 
ATOM   207  N N     . ARG A 1 32  ? 147.162 139.116 127.843 1.00 16.74  ? 32  ARG A N     1 
ATOM   208  C CA    . ARG A 1 32  ? 148.342 139.750 128.413 1.00 19.81  ? 32  ARG A CA    1 
ATOM   209  C C     . ARG A 1 32  ? 149.050 140.675 127.432 1.00 20.77  ? 32  ARG A C     1 
ATOM   210  O O     . ARG A 1 32  ? 150.009 141.348 127.824 1.00 20.49  ? 32  ARG A O     1 
ATOM   211  C CB    . ARG A 1 32  ? 149.316 138.681 128.914 1.00 21.75  ? 32  ARG A CB    1 
ATOM   212  C CG    . ARG A 1 32  ? 148.757 137.824 130.039 1.00 25.18  ? 32  ARG A CG    1 
ATOM   213  C CD    . ARG A 1 32  ? 149.785 136.828 130.546 1.00 22.91  ? 32  ARG A CD    1 
ATOM   214  N NE    . ARG A 1 32  ? 150.194 135.890 129.507 1.00 24.82  ? 32  ARG A NE    1 
ATOM   215  C CZ    . ARG A 1 32  ? 149.802 134.625 129.443 1.00 25.51  ? 32  ARG A CZ    1 
ATOM   216  N NH1   . ARG A 1 32  ? 148.981 134.110 130.344 1.00 22.61  ? 32  ARG A NH1   1 
ATOM   217  N NH2   . ARG A 1 32  ? 150.243 133.858 128.451 1.00 21.36  ? 32  ARG A NH2   1 
ATOM   218  N N     . GLU A 1 33  ? 148.608 140.723 126.179 1.00 17.21  ? 33  GLU A N     1 
ATOM   219  C CA    . GLU A 1 33  ? 149.208 141.609 125.193 1.00 14.02  ? 33  GLU A CA    1 
ATOM   220  C C     . GLU A 1 33  ? 148.628 143.013 125.311 1.00 14.79  ? 33  GLU A C     1 
ATOM   221  O O     . GLU A 1 33  ? 147.439 143.190 125.592 1.00 15.57  ? 33  GLU A O     1 
ATOM   222  C CB    . GLU A 1 33  ? 148.983 141.067 123.781 1.00 15.36  ? 33  GLU A CB    1 
ATOM   223  N N     . VAL A 1 34  ? 149.478 144.011 125.096 1.00 14.31  ? 34  VAL A N     1 
ATOM   224  C CA    . VAL A 1 34  ? 149.079 145.411 125.165 1.00 6.08   ? 34  VAL A CA    1 
ATOM   225  C C     . VAL A 1 34  ? 148.710 145.876 123.763 1.00 10.26  ? 34  VAL A C     1 
ATOM   226  O O     . VAL A 1 34  ? 149.549 145.865 122.856 1.00 11.92  ? 34  VAL A O     1 
ATOM   227  C CB    . VAL A 1 34  ? 150.199 146.279 125.756 1.00 6.77   ? 34  VAL A CB    1 
ATOM   228  C CG1   . VAL A 1 34  ? 149.735 147.719 125.897 1.00 9.93   ? 34  VAL A CG1   1 
ATOM   229  C CG2   . VAL A 1 34  ? 150.650 145.722 127.096 1.00 11.39  ? 34  VAL A CG2   1 
ATOM   230  N N     . LYS A 1 35  ? 147.463 146.305 123.591 1.00 13.00  ? 35  LYS A N     1 
ATOM   231  C CA    . LYS A 1 35  ? 146.946 146.713 122.291 1.00 3.29   ? 35  LYS A CA    1 
ATOM   232  C C     . LYS A 1 35  ? 146.963 148.234 122.190 1.00 6.36   ? 35  LYS A C     1 
ATOM   233  O O     . LYS A 1 35  ? 146.350 148.929 123.011 1.00 16.04  ? 35  LYS A O     1 
ATOM   234  C CB    . LYS A 1 35  ? 145.534 146.171 122.074 1.00 7.65   ? 35  LYS A CB    1 
ATOM   235  C CG    . LYS A 1 35  ? 145.482 144.669 121.849 1.00 8.45   ? 35  LYS A CG    1 
ATOM   236  C CD    . LYS A 1 35  ? 144.074 144.127 122.033 1.00 13.89  ? 35  LYS A CD    1 
ATOM   237  C CE    . LYS A 1 35  ? 143.207 144.410 120.816 1.00 13.30  ? 35  LYS A CE    1 
ATOM   238  N NZ    . LYS A 1 35  ? 143.239 143.288 119.836 1.00 8.61   ? 35  LYS A NZ    1 
ATOM   239  N N     . LEU A 1 36  ? 147.658 148.743 121.178 1.00 4.23   ? 36  LEU A N     1 
ATOM   240  C CA    . LEU A 1 36  ? 147.763 150.170 120.926 1.00 5.03   ? 36  LEU A CA    1 
ATOM   241  C C     . LEU A 1 36  ? 147.204 150.469 119.545 1.00 4.72   ? 36  LEU A C     1 
ATOM   242  O O     . LEU A 1 36  ? 147.446 149.721 118.595 1.00 6.76   ? 36  LEU A O     1 
ATOM   243  C CB    . LEU A 1 36  ? 149.216 150.642 121.019 1.00 6.83   ? 36  LEU A CB    1 
ATOM   244  C CG    . LEU A 1 36  ? 149.959 150.269 122.302 1.00 4.89   ? 36  LEU A CG    1 
ATOM   245  C CD1   . LEU A 1 36  ? 151.448 150.520 122.150 1.00 12.10  ? 36  LEU A CD1   1 
ATOM   246  C CD2   . LEU A 1 36  ? 149.401 151.040 123.482 1.00 0.00   ? 36  LEU A CD2   1 
ATOM   247  N N     . LEU A 1 37  ? 146.439 151.548 119.441 1.00 2.54   ? 37  LEU A N     1 
ATOM   248  C CA    . LEU A 1 37  ? 145.882 151.997 118.169 1.00 1.00   ? 37  LEU A CA    1 
ATOM   249  C C     . LEU A 1 37  ? 146.611 153.270 117.762 1.00 1.48   ? 37  LEU A C     1 
ATOM   250  O O     . LEU A 1 37  ? 146.485 154.301 118.427 1.00 11.82  ? 37  LEU A O     1 
ATOM   251  C CB    . LEU A 1 37  ? 144.377 152.231 118.281 1.00 0.00   ? 37  LEU A CB    1 
ATOM   252  C CG    . LEU A 1 37  ? 143.698 152.886 117.077 1.00 3.75   ? 37  LEU A CG    1 
ATOM   253  C CD1   . LEU A 1 37  ? 143.901 152.052 115.823 1.00 5.70   ? 37  LEU A CD1   1 
ATOM   254  C CD2   . LEU A 1 37  ? 142.219 153.096 117.349 1.00 7.82   ? 37  LEU A CD2   1 
ATOM   255  N N     . LEU A 1 38  ? 147.384 153.198 116.681 1.00 0.00   ? 38  LEU A N     1 
ATOM   256  C CA    . LEU A 1 38  ? 148.181 154.328 116.223 1.00 2.67   ? 38  LEU A CA    1 
ATOM   257  C C     . LEU A 1 38  ? 147.333 155.197 115.303 1.00 5.61   ? 38  LEU A C     1 
ATOM   258  O O     . LEU A 1 38  ? 146.801 154.712 114.298 1.00 16.21  ? 38  LEU A O     1 
ATOM   259  C CB    . LEU A 1 38  ? 149.439 153.841 115.507 1.00 3.62   ? 38  LEU A CB    1 
ATOM   260  C CG    . LEU A 1 38  ? 150.405 154.913 115.001 1.00 11.13  ? 38  LEU A CG    1 
ATOM   261  C CD1   . LEU A 1 38  ? 151.005 155.683 116.164 1.00 8.19   ? 38  LEU A CD1   1 
ATOM   262  C CD2   . LEU A 1 38  ? 151.497 154.287 114.151 1.00 16.43  ? 38  LEU A CD2   1 
ATOM   263  N N     . LEU A 1 39  ? 147.211 156.477 115.646 1.00 1.40   ? 39  LEU A N     1 
ATOM   264  C CA    . LEU A 1 39  ? 146.373 157.403 114.902 1.00 5.77   ? 39  LEU A CA    1 
ATOM   265  C C     . LEU A 1 39  ? 147.130 158.703 114.675 1.00 11.56  ? 39  LEU A C     1 
ATOM   266  O O     . LEU A 1 39  ? 148.065 159.041 115.406 1.00 12.13  ? 39  LEU A O     1 
ATOM   267  C CB    . LEU A 1 39  ? 145.052 157.678 115.632 1.00 4.30   ? 39  LEU A CB    1 
ATOM   268  C CG    . LEU A 1 39  ? 143.983 156.591 115.511 1.00 5.92   ? 39  LEU A CG    1 
ATOM   269  C CD1   . LEU A 1 39  ? 142.985 156.692 116.648 1.00 3.38   ? 39  LEU A CD1   1 
ATOM   270  C CD2   . LEU A 1 39  ? 143.278 156.678 114.168 1.00 11.78  ? 39  LEU A CD2   1 
ATOM   271  N N     . GLY A 1 40  ? 146.717 159.422 113.642 1.00 15.19  ? 40  GLY A N     1 
ATOM   272  C CA    . GLY A 1 40  ? 147.333 160.693 113.317 1.00 16.59  ? 40  GLY A CA    1 
ATOM   273  C C     . GLY A 1 40  ? 146.623 161.325 112.140 1.00 22.52  ? 40  GLY A C     1 
ATOM   274  O O     . GLY A 1 40  ? 145.855 160.673 111.424 1.00 23.94  ? 40  GLY A O     1 
ATOM   275  N N     . ALA A 1 41  ? 146.899 162.614 111.952 1.00 28.43  ? 41  ALA A N     1 
ATOM   276  C CA    . ALA A 1 41  ? 146.280 163.373 110.873 1.00 32.04  ? 41  ALA A CA    1 
ATOM   277  C C     . ALA A 1 41  ? 146.945 163.143 109.523 1.00 34.88  ? 41  ALA A C     1 
ATOM   278  O O     . ALA A 1 41  ? 146.435 163.632 108.510 1.00 33.94  ? 41  ALA A O     1 
ATOM   279  C CB    . ALA A 1 41  ? 146.297 164.867 111.203 1.00 28.70  ? 41  ALA A CB    1 
ATOM   280  N N     . GLY A 1 42  ? 148.059 162.418 109.482 1.00 39.72  ? 42  GLY A N     1 
ATOM   281  C CA    . GLY A 1 42  ? 148.779 162.205 108.243 1.00 37.69  ? 42  GLY A CA    1 
ATOM   282  C C     . GLY A 1 42  ? 150.260 161.984 108.467 1.00 41.66  ? 42  GLY A C     1 
ATOM   283  O O     . GLY A 1 42  ? 150.653 161.093 109.226 1.00 41.51  ? 42  GLY A O     1 
ATOM   284  N N     . GLU A 1 43  ? 151.095 162.789 107.809 1.00 42.72  ? 43  GLU A N     1 
ATOM   285  C CA    . GLU A 1 43  ? 152.545 162.713 107.979 1.00 40.28  ? 43  GLU A CA    1 
ATOM   286  C C     . GLU A 1 43  ? 152.968 163.426 109.266 1.00 41.54  ? 43  GLU A C     1 
ATOM   287  O O     . GLU A 1 43  ? 153.710 164.408 109.265 1.00 41.66  ? 43  GLU A O     1 
ATOM   288  C CB    . GLU A 1 43  ? 153.249 163.298 106.761 1.00 37.14  ? 43  GLU A CB    1 
ATOM   289  N N     . SER A 1 44  ? 152.471 162.903 110.385 1.00 35.19  ? 44  SER A N     1 
ATOM   290  C CA    . SER A 1 44  ? 152.729 163.463 111.704 1.00 32.55  ? 44  SER A CA    1 
ATOM   291  C C     . SER A 1 44  ? 153.824 162.719 112.455 1.00 31.84  ? 44  SER A C     1 
ATOM   292  O O     . SER A 1 44  ? 154.024 162.972 113.647 1.00 30.40  ? 44  SER A O     1 
ATOM   293  C CB    . SER A 1 44  ? 151.442 163.472 112.532 1.00 29.23  ? 44  SER A CB    1 
ATOM   294  O OG    . SER A 1 44  ? 150.563 164.495 112.098 1.00 32.97  ? 44  SER A OG    1 
ATOM   295  N N     . GLY A 1 45  ? 154.535 161.815 111.791 1.00 28.59  ? 45  GLY A N     1 
ATOM   296  C CA    . GLY A 1 45  ? 155.550 161.015 112.438 1.00 29.22  ? 45  GLY A CA    1 
ATOM   297  C C     . GLY A 1 45  ? 155.133 159.609 112.801 1.00 31.24  ? 45  GLY A C     1 
ATOM   298  O O     . GLY A 1 45  ? 155.861 158.942 113.545 1.00 31.67  ? 45  GLY A O     1 
ATOM   299  N N     . LYS A 1 46  ? 153.983 159.140 112.309 1.00 25.54  ? 46  LYS A N     1 
ATOM   300  C CA    . LYS A 1 46  ? 153.545 157.781 112.611 1.00 22.12  ? 46  LYS A CA    1 
ATOM   301  C C     . LYS A 1 46  ? 154.521 156.750 112.059 1.00 26.21  ? 46  LYS A C     1 
ATOM   302  O O     . LYS A 1 46  ? 154.799 155.737 112.710 1.00 28.48  ? 46  LYS A O     1 
ATOM   303  C CB    . LYS A 1 46  ? 152.143 157.547 112.050 1.00 23.32  ? 46  LYS A CB    1 
ATOM   304  C CG    . LYS A 1 46  ? 151.069 158.410 112.687 1.00 24.62  ? 46  LYS A CG    1 
ATOM   305  C CD    . LYS A 1 46  ? 149.775 158.353 111.895 1.00 22.59  ? 46  LYS A CD    1 
ATOM   306  C CE    . LYS A 1 46  ? 149.194 156.951 111.889 1.00 19.91  ? 46  LYS A CE    1 
ATOM   307  N NZ    . LYS A 1 46  ? 148.066 156.822 110.927 1.00 25.00  ? 46  LYS A NZ    1 
ATOM   308  N N     . SER A 1 47  ? 155.043 156.987 110.852 1.00 28.64  ? 47  SER A N     1 
ATOM   309  C CA    . SER A 1 47  ? 156.020 156.068 110.278 1.00 29.99  ? 47  SER A CA    1 
ATOM   310  C C     . SER A 1 47  ? 157.289 156.015 111.120 1.00 33.03  ? 47  SER A C     1 
ATOM   311  O O     . SER A 1 47  ? 157.835 154.933 111.366 1.00 31.90  ? 47  SER A O     1 
ATOM   312  C CB    . SER A 1 47  ? 156.345 156.478 108.841 1.00 28.37  ? 47  SER A CB    1 
ATOM   313  N N     . THR A 1 48  ? 157.771 157.175 111.575 1.00 37.26  ? 48  THR A N     1 
ATOM   314  C CA    . THR A 1 48  ? 158.958 157.201 112.424 1.00 37.13  ? 48  THR A CA    1 
ATOM   315  C C     . THR A 1 48  ? 158.700 156.501 113.753 1.00 34.97  ? 48  THR A C     1 
ATOM   316  O O     . THR A 1 48  ? 159.565 155.778 114.261 1.00 35.02  ? 48  THR A O     1 
ATOM   317  C CB    . THR A 1 48  ? 159.406 158.643 112.659 1.00 30.61  ? 48  THR A CB    1 
ATOM   318  N N     . ILE A 1 49  ? 157.514 156.710 114.331 1.00 31.92  ? 49  ILE A N     1 
ATOM   319  C CA    . ILE A 1 49  ? 157.169 156.057 115.591 1.00 34.85  ? 49  ILE A CA    1 
ATOM   320  C C     . ILE A 1 49  ? 157.138 154.545 115.416 1.00 36.31  ? 49  ILE A C     1 
ATOM   321  O O     . ILE A 1 49  ? 157.650 153.796 116.256 1.00 34.09  ? 49  ILE A O     1 
ATOM   322  C CB    . ILE A 1 49  ? 155.827 156.600 116.119 1.00 32.87  ? 49  ILE A CB    1 
ATOM   323  C CG1   . ILE A 1 49  ? 156.011 158.006 116.693 1.00 31.76  ? 49  ILE A CG1   1 
ATOM   324  C CG2   . ILE A 1 49  ? 155.237 155.666 117.165 1.00 30.23  ? 49  ILE A CG2   1 
ATOM   325  C CD1   . ILE A 1 49  ? 156.916 158.059 117.904 1.00 31.53  ? 49  ILE A CD1   1 
ATOM   326  N N     . VAL A 1 50  ? 156.543 154.072 114.318 1.00 35.43  ? 50  VAL A N     1 
ATOM   327  C CA    . VAL A 1 50  ? 156.492 152.635 114.059 1.00 33.98  ? 50  VAL A CA    1 
ATOM   328  C C     . VAL A 1 50  ? 157.895 152.079 113.848 1.00 38.06  ? 50  VAL A C     1 
ATOM   329  O O     . VAL A 1 50  ? 158.224 150.988 114.328 1.00 41.14  ? 50  VAL A O     1 
ATOM   330  C CB    . VAL A 1 50  ? 155.579 152.341 112.854 1.00 30.02  ? 50  VAL A CB    1 
ATOM   331  N N     . LYS A 1 51  ? 158.740 152.815 113.120 1.00 37.76  ? 51  LYS A N     1 
ATOM   332  C CA    . LYS A 1 51  ? 160.099 152.349 112.864 1.00 37.35  ? 51  LYS A CA    1 
ATOM   333  C C     . LYS A 1 51  ? 160.908 152.254 114.152 1.00 38.69  ? 51  LYS A C     1 
ATOM   334  O O     . LYS A 1 51  ? 161.644 151.282 114.360 1.00 39.02  ? 51  LYS A O     1 
ATOM   335  C CB    . LYS A 1 51  ? 160.790 153.275 111.864 1.00 36.81  ? 51  LYS A CB    1 
ATOM   336  N N     . GLN A 1 52  ? 160.788 153.251 115.029 1.00 37.30  ? 52  GLN A N     1 
ATOM   337  C CA    . GLN A 1 52  ? 161.550 153.252 116.270 1.00 38.66  ? 52  GLN A CA    1 
ATOM   338  C C     . GLN A 1 52  ? 160.931 152.379 117.353 1.00 39.35  ? 52  GLN A C     1 
ATOM   339  O O     . GLN A 1 52  ? 161.568 152.164 118.390 1.00 40.97  ? 52  GLN A O     1 
ATOM   340  C CB    . GLN A 1 52  ? 161.708 154.681 116.795 1.00 39.17  ? 52  GLN A CB    1 
ATOM   341  C CG    . GLN A 1 52  ? 160.442 155.272 117.389 1.00 37.19  ? 52  GLN A CG    1 
ATOM   342  C CD    . GLN A 1 52  ? 160.552 156.765 117.618 1.00 40.65  ? 52  GLN A CD    1 
ATOM   343  O OE1   . GLN A 1 52  ? 161.079 157.212 118.636 1.00 41.85  ? 52  GLN A OE1   1 
ATOM   344  N NE2   . GLN A 1 52  ? 160.055 157.548 116.667 1.00 39.39  ? 52  GLN A NE2   1 
ATOM   345  N N     . MET A 1 53  ? 159.719 151.875 117.145 1.00 36.56  ? 53  MET A N     1 
ATOM   346  C CA    . MET A 1 53  ? 159.067 151.019 118.129 1.00 36.54  ? 53  MET A CA    1 
ATOM   347  C C     . MET A 1 53  ? 158.681 149.678 117.516 1.00 37.99  ? 53  MET A C     1 
ATOM   348  O O     . MET A 1 53  ? 159.538 148.928 117.050 1.00 37.96  ? 53  MET A O     1 
ATOM   349  C CB    . MET A 1 53  ? 157.831 151.710 118.708 1.00 36.69  ? 53  MET A CB    1 
ATOM   350  C CG    . MET A 1 53  ? 158.128 153.032 119.398 1.00 38.46  ? 53  MET A CG    1 
ATOM   351  S SD    . MET A 1 53  ? 156.644 153.846 120.017 1.00 46.76  ? 53  MET A SD    1 
ATOM   352  C CE    . MET A 1 53  ? 155.819 152.475 120.821 1.00 38.89  ? 53  MET A CE    1 
ATOM   353  N N     . THR A 1 182 ? 147.932 146.627 102.732 1.00 28.14  ? 182 THR A N     1 
ATOM   354  C CA    . THR A 1 182 ? 147.153 147.695 102.117 1.00 30.65  ? 182 THR A CA    1 
ATOM   355  C C     . THR A 1 182 ? 146.093 148.225 103.078 1.00 31.62  ? 182 THR A C     1 
ATOM   356  O O     . THR A 1 182 ? 145.541 149.306 102.873 1.00 30.23  ? 182 THR A O     1 
ATOM   357  C CB    . THR A 1 182 ? 146.470 147.219 100.819 1.00 28.93  ? 182 THR A CB    1 
ATOM   358  O OG1   . THR A 1 182 ? 145.628 148.260 100.308 1.00 30.49  ? 182 THR A OG1   1 
ATOM   359  C CG2   . THR A 1 182 ? 145.634 145.976 101.080 1.00 27.17  ? 182 THR A CG2   1 
ATOM   360  N N     . GLY A 1 183 ? 145.813 147.455 104.126 1.00 19.38  ? 183 GLY A N     1 
ATOM   361  C CA    . GLY A 1 183 ? 144.832 147.854 105.116 1.00 14.37  ? 183 GLY A CA    1 
ATOM   362  C C     . GLY A 1 183 ? 145.429 148.067 106.491 1.00 16.40  ? 183 GLY A C     1 
ATOM   363  O O     . GLY A 1 183 ? 146.276 148.945 106.681 1.00 24.13  ? 183 GLY A O     1 
ATOM   364  N N     . ILE A 1 184 ? 144.983 147.269 107.463 1.00 14.71  ? 184 ILE A N     1 
ATOM   365  C CA    . ILE A 1 184 ? 145.532 147.356 108.809 1.00 8.78   ? 184 ILE A CA    1 
ATOM   366  C C     . ILE A 1 184 ? 146.991 146.921 108.796 1.00 9.50   ? 184 ILE A C     1 
ATOM   367  O O     . ILE A 1 184 ? 147.380 145.991 108.077 1.00 15.28  ? 184 ILE A O     1 
ATOM   368  C CB    . ILE A 1 184 ? 144.693 146.506 109.779 1.00 9.97   ? 184 ILE A CB    1 
ATOM   369  C CG1   . ILE A 1 184 ? 145.169 146.693 111.221 1.00 8.25   ? 184 ILE A CG1   1 
ATOM   370  C CG2   . ILE A 1 184 ? 144.720 145.036 109.381 1.00 13.44  ? 184 ILE A CG2   1 
ATOM   371  C CD1   . ILE A 1 184 ? 144.909 148.068 111.772 1.00 10.69  ? 184 ILE A CD1   1 
ATOM   372  N N     . VAL A 1 185 ? 147.817 147.613 109.578 1.00 9.00   ? 185 VAL A N     1 
ATOM   373  C CA    . VAL A 1 185 ? 149.225 147.269 109.736 1.00 8.95   ? 185 VAL A CA    1 
ATOM   374  C C     . VAL A 1 185 ? 149.464 146.924 111.198 1.00 10.19  ? 185 VAL A C     1 
ATOM   375  O O     . VAL A 1 185 ? 149.073 147.684 112.088 1.00 15.39  ? 185 VAL A O     1 
ATOM   376  C CB    . VAL A 1 185 ? 150.147 148.416 109.284 1.00 9.86   ? 185 VAL A CB    1 
ATOM   377  C CG1   . VAL A 1 185 ? 151.602 148.060 109.538 1.00 12.39  ? 185 VAL A CG1   1 
ATOM   378  C CG2   . VAL A 1 185 ? 149.920 148.730 107.815 1.00 13.38  ? 185 VAL A CG2   1 
ATOM   379  N N     . GLU A 1 186 ? 150.094 145.781 111.448 1.00 16.14  ? 186 GLU A N     1 
ATOM   380  C CA    . GLU A 1 186 ? 150.354 145.319 112.804 1.00 15.26  ? 186 GLU A CA    1 
ATOM   381  C C     . GLU A 1 186 ? 151.853 145.288 113.057 1.00 18.40  ? 186 GLU A C     1 
ATOM   382  O O     . GLU A 1 186 ? 152.606 144.687 112.284 1.00 24.12  ? 186 GLU A O     1 
ATOM   383  C CB    . GLU A 1 186 ? 149.747 143.935 113.043 1.00 19.33  ? 186 GLU A CB    1 
ATOM   384  C CG    . GLU A 1 186 ? 148.310 143.800 112.569 1.00 21.39  ? 186 GLU A CG    1 
ATOM   385  C CD    . GLU A 1 186 ? 147.611 142.599 113.173 1.00 26.98  ? 186 GLU A CD    1 
ATOM   386  O OE1   . GLU A 1 186 ? 148.256 141.862 113.947 1.00 25.41  ? 186 GLU A OE1   1 
ATOM   387  O OE2   . GLU A 1 186 ? 146.416 142.392 112.873 1.00 25.79  ? 186 GLU A OE2   1 
ATOM   388  N N     . THR A 1 187 ? 152.280 145.936 114.137 1.00 20.52  ? 187 THR A N     1 
ATOM   389  C CA    . THR A 1 187 ? 153.670 145.925 114.575 1.00 21.80  ? 187 THR A CA    1 
ATOM   390  C C     . THR A 1 187 ? 153.735 145.270 115.948 1.00 19.01  ? 187 THR A C     1 
ATOM   391  O O     . THR A 1 187 ? 153.075 145.726 116.887 1.00 22.04  ? 187 THR A O     1 
ATOM   392  C CB    . THR A 1 187 ? 154.243 147.342 114.625 1.00 22.89  ? 187 THR A CB    1 
ATOM   393  O OG1   . THR A 1 187 ? 154.131 147.950 113.333 1.00 21.46  ? 187 THR A OG1   1 
ATOM   394  C CG2   . THR A 1 187 ? 155.706 147.311 115.038 1.00 25.58  ? 187 THR A CG2   1 
ATOM   395  N N     . HIS A 1 188 ? 154.524 144.208 116.062 1.00 21.48  ? 188 HIS A N     1 
ATOM   396  C CA    . HIS A 1 188 ? 154.657 143.451 117.298 1.00 23.05  ? 188 HIS A CA    1 
ATOM   397  C C     . HIS A 1 188 ? 156.051 143.667 117.867 1.00 26.26  ? 188 HIS A C     1 
ATOM   398  O O     . HIS A 1 188 ? 157.047 143.473 117.162 1.00 29.88  ? 188 HIS A O     1 
ATOM   399  C CB    . HIS A 1 188 ? 154.416 141.960 117.053 1.00 21.22  ? 188 HIS A CB    1 
ATOM   400  C CG    . HIS A 1 188 ? 153.076 141.653 116.463 1.00 28.29  ? 188 HIS A CG    1 
ATOM   401  N ND1   . HIS A 1 188 ? 151.995 141.268 117.228 1.00 29.81  ? 188 HIS A ND1   1 
ATOM   402  C CD2   . HIS A 1 188 ? 152.640 141.675 115.182 1.00 31.31  ? 188 HIS A CD2   1 
ATOM   403  C CE1   . HIS A 1 188 ? 150.953 141.065 116.442 1.00 24.10  ? 188 HIS A CE1   1 
ATOM   404  N NE2   . HIS A 1 188 ? 151.317 141.306 115.196 1.00 26.76  ? 188 HIS A NE2   1 
ATOM   405  N N     . PHE A 1 189 ? 156.125 144.070 119.134 1.00 20.38  ? 189 PHE A N     1 
ATOM   406  C CA    . PHE A 1 189 ? 157.433 144.251 119.752 1.00 24.38  ? 189 PHE A CA    1 
ATOM   407  C C     . PHE A 1 189 ? 157.352 144.005 121.251 1.00 25.38  ? 189 PHE A C     1 
ATOM   408  O O     . PHE A 1 189 ? 156.378 144.385 121.900 1.00 25.21  ? 189 PHE A O     1 
ATOM   409  C CB    . PHE A 1 189 ? 158.008 145.647 119.468 1.00 24.52  ? 189 PHE A CB    1 
ATOM   410  C CG    . PHE A 1 189 ? 157.146 146.781 119.946 1.00 22.19  ? 189 PHE A CG    1 
ATOM   411  C CD1   . PHE A 1 189 ? 156.078 147.228 119.185 1.00 23.82  ? 189 PHE A CD1   1 
ATOM   412  C CD2   . PHE A 1 189 ? 157.419 147.417 121.145 1.00 23.12  ? 189 PHE A CD2   1 
ATOM   413  C CE1   . PHE A 1 189 ? 155.291 148.276 119.618 1.00 27.48  ? 189 PHE A CE1   1 
ATOM   414  C CE2   . PHE A 1 189 ? 156.636 148.467 121.584 1.00 24.79  ? 189 PHE A CE2   1 
ATOM   415  C CZ    . PHE A 1 189 ? 155.572 148.898 120.818 1.00 27.21  ? 189 PHE A CZ    1 
ATOM   416  N N     . THR A 1 190 ? 158.388 143.373 121.793 1.00 25.66  ? 190 THR A N     1 
ATOM   417  C CA    . THR A 1 190 ? 158.450 143.041 123.210 1.00 20.88  ? 190 THR A CA    1 
ATOM   418  C C     . THR A 1 190 ? 159.382 144.010 123.924 1.00 20.01  ? 190 THR A C     1 
ATOM   419  O O     . THR A 1 190 ? 160.541 144.172 123.527 1.00 25.24  ? 190 THR A O     1 
ATOM   420  C CB    . THR A 1 190 ? 158.926 141.603 123.417 1.00 25.33  ? 190 THR A CB    1 
ATOM   421  O OG1   . THR A 1 190 ? 158.059 140.704 122.714 1.00 23.53  ? 190 THR A OG1   1 
ATOM   422  C CG2   . THR A 1 190 ? 158.921 141.248 124.896 1.00 21.85  ? 190 THR A CG2   1 
ATOM   423  N N     . PHE A 1 191 ? 158.871 144.652 124.972 1.00 18.42  ? 191 PHE A N     1 
ATOM   424  C CA    . PHE A 1 191 ? 159.644 145.592 125.774 1.00 21.44  ? 191 PHE A CA    1 
ATOM   425  C C     . PHE A 1 191 ? 159.352 145.328 127.242 1.00 22.79  ? 191 PHE A C     1 
ATOM   426  O O     . PHE A 1 191 ? 158.189 145.359 127.657 1.00 24.23  ? 191 PHE A O     1 
ATOM   427  C CB    . PHE A 1 191 ? 159.305 147.040 125.405 1.00 20.98  ? 191 PHE A CB    1 
ATOM   428  C CG    . PHE A 1 191 ? 160.145 148.062 126.116 1.00 19.00  ? 191 PHE A CG    1 
ATOM   429  C CD1   . PHE A 1 191 ? 161.402 148.395 125.642 1.00 23.51  ? 191 PHE A CD1   1 
ATOM   430  C CD2   . PHE A 1 191 ? 159.673 148.698 127.252 1.00 16.86  ? 191 PHE A CD2   1 
ATOM   431  C CE1   . PHE A 1 191 ? 162.177 149.337 126.291 1.00 21.97  ? 191 PHE A CE1   1 
ATOM   432  C CE2   . PHE A 1 191 ? 160.442 149.642 127.905 1.00 20.18  ? 191 PHE A CE2   1 
ATOM   433  C CZ    . PHE A 1 191 ? 161.696 149.961 127.424 1.00 21.24  ? 191 PHE A CZ    1 
ATOM   434  N N     . LYS A 1 192 ? 160.405 145.061 128.014 1.00 23.05  ? 192 LYS A N     1 
ATOM   435  C CA    . LYS A 1 192 ? 160.311 144.847 129.459 1.00 19.97  ? 192 LYS A CA    1 
ATOM   436  C C     . LYS A 1 192 ? 159.242 143.811 129.802 1.00 20.49  ? 192 LYS A C     1 
ATOM   437  O O     . LYS A 1 192 ? 158.368 144.033 130.644 1.00 19.55  ? 192 LYS A O     1 
ATOM   438  C CB    . LYS A 1 192 ? 160.053 146.166 130.188 1.00 19.28  ? 192 LYS A CB    1 
ATOM   439  C CG    . LYS A 1 192 ? 161.278 147.061 130.283 1.00 20.36  ? 192 LYS A CG    1 
ATOM   440  C CD    . LYS A 1 192 ? 161.036 148.232 131.219 1.00 23.02  ? 192 LYS A CD    1 
ATOM   441  C CE    . LYS A 1 192 ? 162.344 148.898 131.614 1.00 22.26  ? 192 LYS A CE    1 
ATOM   442  N NZ    . LYS A 1 192 ? 162.940 149.663 130.486 1.00 23.10  ? 192 LYS A NZ    1 
ATOM   443  N N     . ASP A 1 193 ? 159.316 142.667 129.121 1.00 22.34  ? 193 ASP A N     1 
ATOM   444  C CA    . ASP A 1 193 ? 158.420 141.530 129.329 1.00 25.69  ? 193 ASP A CA    1 
ATOM   445  C C     . ASP A 1 193 ? 156.964 141.862 129.018 1.00 25.05  ? 193 ASP A C     1 
ATOM   446  O O     . ASP A 1 193 ? 156.054 141.179 129.499 1.00 22.02  ? 193 ASP A O     1 
ATOM   447  C CB    . ASP A 1 193 ? 158.542 140.977 130.755 1.00 24.69  ? 193 ASP A CB    1 
ATOM   448  N N     . LEU A 1 194 ? 156.718 142.901 128.224 1.00 20.66  ? 194 LEU A N     1 
ATOM   449  C CA    . LEU A 1 194 ? 155.379 143.231 127.753 1.00 18.45  ? 194 LEU A CA    1 
ATOM   450  C C     . LEU A 1 194 ? 155.360 143.172 126.234 1.00 20.81  ? 194 LEU A C     1 
ATOM   451  O O     . LEU A 1 194 ? 156.184 143.812 125.576 1.00 24.02  ? 194 LEU A O     1 
ATOM   452  C CB    . LEU A 1 194 ? 154.940 144.617 128.236 1.00 20.27  ? 194 LEU A CB    1 
ATOM   453  C CG    . LEU A 1 194 ? 154.241 144.682 129.595 1.00 21.48  ? 194 LEU A CG    1 
ATOM   454  C CD1   . LEU A 1 194 ? 153.722 146.085 129.863 1.00 17.60  ? 194 LEU A CD1   1 
ATOM   455  C CD2   . LEU A 1 194 ? 153.110 143.669 129.665 1.00 19.93  ? 194 LEU A CD2   1 
ATOM   456  N N     . HIS A 1 195 ? 154.420 142.410 125.682 1.00 19.32  ? 195 HIS A N     1 
ATOM   457  C CA    . HIS A 1 195 ? 154.285 142.273 124.238 1.00 17.24  ? 195 HIS A CA    1 
ATOM   458  C C     . HIS A 1 195 ? 153.263 143.287 123.740 1.00 15.78  ? 195 HIS A C     1 
ATOM   459  O O     . HIS A 1 195 ? 152.099 143.253 124.151 1.00 18.63  ? 195 HIS A O     1 
ATOM   460  C CB    . HIS A 1 195 ? 153.865 140.852 123.868 1.00 19.46  ? 195 HIS A CB    1 
ATOM   461  C CG    . HIS A 1 195 ? 153.792 140.607 122.392 1.00 23.08  ? 195 HIS A CG    1 
ATOM   462  N ND1   . HIS A 1 195 ? 154.912 140.540 121.593 1.00 27.06  ? 195 HIS A ND1   1 
ATOM   463  C CD2   . HIS A 1 195 ? 152.733 140.411 121.572 1.00 18.80  ? 195 HIS A CD2   1 
ATOM   464  C CE1   . HIS A 1 195 ? 154.547 140.315 120.343 1.00 23.63  ? 195 HIS A CE1   1 
ATOM   465  N NE2   . HIS A 1 195 ? 153.229 140.232 120.304 1.00 18.84  ? 195 HIS A NE2   1 
ATOM   466  N N     . PHE A 1 196 ? 153.695 144.182 122.857 1.00 13.28  ? 196 PHE A N     1 
ATOM   467  C CA    . PHE A 1 196 ? 152.865 145.255 122.336 1.00 14.19  ? 196 PHE A CA    1 
ATOM   468  C C     . PHE A 1 196 ? 152.486 144.949 120.896 1.00 15.93  ? 196 PHE A C     1 
ATOM   469  O O     . PHE A 1 196 ? 153.358 144.645 120.070 1.00 24.20  ? 196 PHE A O     1 
ATOM   470  C CB    . PHE A 1 196 ? 153.597 146.596 122.392 1.00 15.68  ? 196 PHE A CB    1 
ATOM   471  C CG    . PHE A 1 196 ? 153.966 147.035 123.774 1.00 16.20  ? 196 PHE A CG    1 
ATOM   472  C CD1   . PHE A 1 196 ? 155.139 146.597 124.364 1.00 17.32  ? 196 PHE A CD1   1 
ATOM   473  C CD2   . PHE A 1 196 ? 153.152 147.901 124.477 1.00 15.75  ? 196 PHE A CD2   1 
ATOM   474  C CE1   . PHE A 1 196 ? 155.485 147.006 125.635 1.00 17.57  ? 196 PHE A CE1   1 
ATOM   475  C CE2   . PHE A 1 196 ? 153.494 148.313 125.745 1.00 15.52  ? 196 PHE A CE2   1 
ATOM   476  C CZ    . PHE A 1 196 ? 154.661 147.865 126.327 1.00 18.54  ? 196 PHE A CZ    1 
ATOM   477  N N     . LYS A 1 197 ? 151.188 145.032 120.607 1.00 13.37  ? 197 LYS A N     1 
ATOM   478  C CA    . LYS A 1 197 ? 150.656 144.998 119.251 1.00 11.63  ? 197 LYS A CA    1 
ATOM   479  C C     . LYS A 1 197 ? 150.130 146.393 118.935 1.00 9.28   ? 197 LYS A C     1 
ATOM   480  O O     . LYS A 1 197 ? 149.157 146.847 119.546 1.00 17.51  ? 197 LYS A O     1 
ATOM   481  C CB    . LYS A 1 197 ? 149.551 143.954 119.114 1.00 9.49   ? 197 LYS A CB    1 
ATOM   482  C CG    . LYS A 1 197 ? 149.966 142.541 119.471 1.00 13.94  ? 197 LYS A CG    1 
ATOM   483  C CD    . LYS A 1 197 ? 148.855 141.557 119.148 1.00 14.59  ? 197 LYS A CD    1 
ATOM   484  C CE    . LYS A 1 197 ? 149.285 140.125 119.409 1.00 19.71  ? 197 LYS A CE    1 
ATOM   485  N NZ    . LYS A 1 197 ? 148.240 139.152 118.986 1.00 17.87  ? 197 LYS A NZ    1 
ATOM   486  N N     . MET A 1 198 ? 150.775 147.068 117.989 1.00 10.28  ? 198 MET A N     1 
ATOM   487  C CA    . MET A 1 198 ? 150.389 148.406 117.563 1.00 8.63   ? 198 MET A CA    1 
ATOM   488  C C     . MET A 1 198 ? 149.733 148.305 116.194 1.00 8.70   ? 198 MET A C     1 
ATOM   489  O O     . MET A 1 198 ? 150.331 147.775 115.252 1.00 11.48  ? 198 MET A O     1 
ATOM   490  C CB    . MET A 1 198 ? 151.601 149.335 117.521 1.00 13.40  ? 198 MET A CB    1 
ATOM   491  C CG    . MET A 1 198 ? 151.283 150.760 117.110 1.00 13.45  ? 198 MET A CG    1 
ATOM   492  S SD    . MET A 1 198 ? 152.674 151.871 117.390 1.00 36.10  ? 198 MET A SD    1 
ATOM   493  C CE    . MET A 1 198 ? 153.889 151.173 116.276 1.00 19.24  ? 198 MET A CE    1 
ATOM   494  N N     . PHE A 1 199 ? 148.508 148.809 116.090 1.00 12.50  ? 199 PHE A N     1 
ATOM   495  C CA    . PHE A 1 199 ? 147.703 148.709 114.882 1.00 6.35   ? 199 PHE A CA    1 
ATOM   496  C C     . PHE A 1 199 ? 147.608 150.083 114.237 1.00 6.52   ? 199 PHE A C     1 
ATOM   497  O O     . PHE A 1 199 ? 147.040 151.010 114.822 1.00 12.23  ? 199 PHE A O     1 
ATOM   498  C CB    . PHE A 1 199 ? 146.311 148.166 115.202 1.00 0.00   ? 199 PHE A CB    1 
ATOM   499  C CG    . PHE A 1 199 ? 146.320 146.999 116.144 1.00 5.85   ? 199 PHE A CG    1 
ATOM   500  C CD1   . PHE A 1 199 ? 146.794 145.766 115.733 1.00 9.51   ? 199 PHE A CD1   1 
ATOM   501  C CD2   . PHE A 1 199 ? 145.861 147.138 117.442 1.00 5.59   ? 199 PHE A CD2   1 
ATOM   502  C CE1   . PHE A 1 199 ? 146.806 144.690 116.598 1.00 8.71   ? 199 PHE A CE1   1 
ATOM   503  C CE2   . PHE A 1 199 ? 145.871 146.067 118.312 1.00 6.72   ? 199 PHE A CE2   1 
ATOM   504  C CZ    . PHE A 1 199 ? 146.343 144.841 117.890 1.00 9.49   ? 199 PHE A CZ    1 
ATOM   505  N N     . ASP A 1 200 ? 148.174 150.207 113.042 1.00 3.69   ? 200 ASP A N     1 
ATOM   506  C CA    . ASP A 1 200 ? 148.111 151.425 112.250 1.00 6.12   ? 200 ASP A CA    1 
ATOM   507  C C     . ASP A 1 200 ? 146.996 151.273 111.223 1.00 13.92  ? 200 ASP A C     1 
ATOM   508  O O     . ASP A 1 200 ? 146.988 150.311 110.444 1.00 18.97  ? 200 ASP A O     1 
ATOM   509  C CB    . ASP A 1 200 ? 149.450 151.697 111.564 1.00 9.89   ? 200 ASP A CB    1 
ATOM   510  C CG    . ASP A 1 200 ? 149.533 153.092 110.977 1.00 16.10  ? 200 ASP A CG    1 
ATOM   511  O OD1   . ASP A 1 200 ? 148.550 153.853 111.095 1.00 19.87  ? 200 ASP A OD1   1 
ATOM   512  O OD2   . ASP A 1 200 ? 150.585 153.428 110.395 1.00 17.13  ? 200 ASP A OD2   1 
ATOM   513  N N     . VAL A 1 201 ? 146.057 152.219 111.234 1.00 15.58  ? 201 VAL A N     1 
ATOM   514  C CA    . VAL A 1 201 ? 144.920 152.211 110.324 1.00 14.54  ? 201 VAL A CA    1 
ATOM   515  C C     . VAL A 1 201 ? 145.089 153.221 109.195 1.00 17.86  ? 201 VAL A C     1 
ATOM   516  O O     . VAL A 1 201 ? 144.121 153.524 108.491 1.00 21.30  ? 201 VAL A O     1 
ATOM   517  C CB    . VAL A 1 201 ? 143.607 152.461 111.082 1.00 12.82  ? 201 VAL A CB    1 
ATOM   518  C CG1   . VAL A 1 201 ? 143.321 151.319 112.039 1.00 10.66  ? 201 VAL A CG1   1 
ATOM   519  C CG2   . VAL A 1 201 ? 143.674 153.783 111.830 1.00 17.05  ? 201 VAL A CG2   1 
ATOM   520  N N     . GLY A 1 202 ? 146.293 153.759 109.014 1.00 20.07  ? 202 GLY A N     1 
ATOM   521  C CA    . GLY A 1 202 ? 146.518 154.690 107.926 1.00 17.93  ? 202 GLY A CA    1 
ATOM   522  C C     . GLY A 1 202 ? 146.362 154.022 106.574 1.00 23.84  ? 202 GLY A C     1 
ATOM   523  O O     . GLY A 1 202 ? 146.657 152.838 106.398 1.00 28.44  ? 202 GLY A O     1 
ATOM   524  N N     . GLY A 1 203 ? 145.886 154.799 105.605 1.00 27.97  ? 203 GLY A N     1 
ATOM   525  C CA    . GLY A 1 203 ? 145.633 154.286 104.278 1.00 30.08  ? 203 GLY A CA    1 
ATOM   526  C C     . GLY A 1 203 ? 144.301 153.593 104.101 1.00 31.34  ? 203 GLY A C     1 
ATOM   527  O O     . GLY A 1 203 ? 144.009 153.129 102.991 1.00 33.86  ? 203 GLY A O     1 
ATOM   528  N N     . GLN A 1 204 ? 143.488 153.496 105.157 1.00 24.93  ? 204 GLN A N     1 
ATOM   529  C CA    . GLN A 1 204 ? 142.168 152.888 105.022 1.00 23.15  ? 204 GLN A CA    1 
ATOM   530  C C     . GLN A 1 204 ? 141.289 153.691 104.070 1.00 25.83  ? 204 GLN A C     1 
ATOM   531  O O     . GLN A 1 204 ? 140.615 153.119 103.205 1.00 26.29  ? 204 GLN A O     1 
ATOM   532  C CB    . GLN A 1 204 ? 141.511 152.764 106.397 1.00 20.56  ? 204 GLN A CB    1 
ATOM   533  C CG    . GLN A 1 204 ? 140.190 152.016 106.396 1.00 24.41  ? 204 GLN A CG    1 
ATOM   534  C CD    . GLN A 1 204 ? 140.307 150.617 105.823 1.00 23.92  ? 204 GLN A CD    1 
ATOM   535  O OE1   . GLN A 1 204 ? 139.890 150.360 104.695 1.00 24.33  ? 204 GLN A OE1   1 
ATOM   536  N NE2   . GLN A 1 204 ? 140.873 149.703 106.603 1.00 20.42  ? 204 GLN A NE2   1 
ATOM   537  N N     . ARG A 1 205 ? 141.291 155.018 104.213 1.00 22.22  ? 205 ARG A N     1 
ATOM   538  C CA    . ARG A 1 205 ? 140.610 155.931 103.291 1.00 26.33  ? 205 ARG A CA    1 
ATOM   539  C C     . ARG A 1 205 ? 139.123 155.614 103.151 1.00 27.60  ? 205 ARG A C     1 
ATOM   540  O O     . ARG A 1 205 ? 138.553 155.736 102.064 1.00 30.22  ? 205 ARG A O     1 
ATOM   541  C CB    . ARG A 1 205 ? 141.284 155.929 101.915 1.00 27.65  ? 205 ARG A CB    1 
ATOM   542  N N     . SER A 1 206 ? 138.482 155.209 104.240 1.00 25.02  ? 206 SER A N     1 
ATOM   543  C CA    . SER A 1 206 ? 137.055 154.917 104.247 1.00 19.73  ? 206 SER A CA    1 
ATOM   544  C C     . SER A 1 206 ? 136.403 155.602 105.447 1.00 20.24  ? 206 SER A C     1 
ATOM   545  O O     . SER A 1 206 ? 137.033 156.387 106.161 1.00 22.12  ? 206 SER A O     1 
ATOM   546  C CB    . SER A 1 206 ? 136.815 153.406 104.258 1.00 19.27  ? 206 SER A CB    1 
ATOM   547  O OG    . SER A 1 206 ? 137.249 152.830 105.477 1.00 19.74  ? 206 SER A OG    1 
ATOM   548  N N     . GLU A 1 207 ? 135.125 155.298 105.665 1.00 19.86  ? 207 GLU A N     1 
ATOM   549  C CA    . GLU A 1 207 ? 134.389 155.859 106.792 1.00 19.26  ? 207 GLU A CA    1 
ATOM   550  C C     . GLU A 1 207 ? 134.924 155.261 108.087 1.00 14.58  ? 207 GLU A C     1 
ATOM   551  O O     . GLU A 1 207 ? 134.784 154.058 108.327 1.00 15.98  ? 207 GLU A O     1 
ATOM   552  C CB    . GLU A 1 207 ? 132.896 155.588 106.639 1.00 12.13  ? 207 GLU A CB    1 
ATOM   553  N N     . ARG A 1 208 ? 135.538 156.102 108.921 1.00 6.46   ? 208 ARG A N     1 
ATOM   554  C CA    . ARG A 1 208 ? 136.123 155.620 110.168 1.00 5.12   ? 208 ARG A CA    1 
ATOM   555  C C     . ARG A 1 208 ? 135.060 155.096 111.124 1.00 5.33   ? 208 ARG A C     1 
ATOM   556  O O     . ARG A 1 208 ? 135.304 154.119 111.841 1.00 5.57   ? 208 ARG A O     1 
ATOM   557  C CB    . ARG A 1 208 ? 136.933 156.735 110.827 1.00 7.42   ? 208 ARG A CB    1 
ATOM   558  C CG    . ARG A 1 208 ? 137.520 156.373 112.180 1.00 11.19  ? 208 ARG A CG    1 
ATOM   559  C CD    . ARG A 1 208 ? 138.642 157.322 112.563 1.00 11.03  ? 208 ARG A CD    1 
ATOM   560  N NE    . ARG A 1 208 ? 138.325 158.705 112.228 1.00 13.42  ? 208 ARG A NE    1 
ATOM   561  C CZ    . ARG A 1 208 ? 137.559 159.498 112.965 1.00 17.25  ? 208 ARG A CZ    1 
ATOM   562  N NH1   . ARG A 1 208 ? 137.012 159.077 114.094 1.00 16.03  ? 208 ARG A NH1   1 
ATOM   563  N NH2   . ARG A 1 208 ? 137.336 160.745 112.559 1.00 13.63  ? 208 ARG A NH2   1 
ATOM   564  N N     . LYS A 1 209 ? 133.879 155.718 111.142 1.00 11.72  ? 209 LYS A N     1 
ATOM   565  C CA    . LYS A 1 209 ? 132.827 155.311 112.066 1.00 9.59   ? 209 LYS A CA    1 
ATOM   566  C C     . LYS A 1 209 ? 132.338 153.891 111.809 1.00 6.44   ? 209 LYS A C     1 
ATOM   567  O O     . LYS A 1 209 ? 131.725 153.290 112.698 1.00 9.46   ? 209 LYS A O     1 
ATOM   568  C CB    . LYS A 1 209 ? 131.651 156.286 111.981 1.00 3.01   ? 209 LYS A CB    1 
ATOM   569  N N     . LYS A 1 210 ? 132.591 153.343 110.623 1.00 5.09   ? 210 LYS A N     1 
ATOM   570  C CA    . LYS A 1 210 ? 132.138 152.001 110.287 1.00 6.63   ? 210 LYS A CA    1 
ATOM   571  C C     . LYS A 1 210 ? 133.083 150.906 110.761 1.00 9.89   ? 210 LYS A C     1 
ATOM   572  O O     . LYS A 1 210 ? 132.703 149.731 110.732 1.00 14.93  ? 210 LYS A O     1 
ATOM   573  C CB    . LYS A 1 210 ? 131.934 151.878 108.774 1.00 2.22   ? 210 LYS A CB    1 
ATOM   574  C CG    . LYS A 1 210 ? 130.658 152.529 108.276 1.00 0.31   ? 210 LYS A CG    1 
ATOM   575  C CD    . LYS A 1 210 ? 129.439 151.787 108.793 1.00 4.51   ? 210 LYS A CD    1 
ATOM   576  C CE    . LYS A 1 210 ? 128.198 152.656 108.749 1.00 6.30   ? 210 LYS A CE    1 
ATOM   577  N NZ    . LYS A 1 210 ? 127.106 152.096 109.590 1.00 6.02   ? 210 LYS A NZ    1 
ATOM   578  N N     . TRP A 1 211 ? 134.296 151.251 111.195 1.00 11.59  ? 211 TRP A N     1 
ATOM   579  C CA    . TRP A 1 211 ? 135.231 150.248 111.684 1.00 5.49   ? 211 TRP A CA    1 
ATOM   580  C C     . TRP A 1 211 ? 135.987 150.663 112.937 1.00 3.56   ? 211 TRP A C     1 
ATOM   581  O O     . TRP A 1 211 ? 136.794 149.870 113.432 1.00 8.83   ? 211 TRP A O     1 
ATOM   582  C CB    . TRP A 1 211 ? 136.243 149.874 110.587 1.00 2.41   ? 211 TRP A CB    1 
ATOM   583  C CG    . TRP A 1 211 ? 136.907 151.049 109.938 1.00 5.39   ? 211 TRP A CG    1 
ATOM   584  C CD1   . TRP A 1 211 ? 136.561 151.632 108.756 1.00 6.05   ? 211 TRP A CD1   1 
ATOM   585  C CD2   . TRP A 1 211 ? 138.038 151.780 110.429 1.00 9.42   ? 211 TRP A CD2   1 
ATOM   586  N NE1   . TRP A 1 211 ? 137.401 152.682 108.481 1.00 9.56   ? 211 TRP A NE1   1 
ATOM   587  C CE2   . TRP A 1 211 ? 138.317 152.794 109.493 1.00 10.28  ? 211 TRP A CE2   1 
ATOM   588  C CE3   . TRP A 1 211 ? 138.840 151.675 111.570 1.00 5.10   ? 211 TRP A CE3   1 
ATOM   589  C CZ2   . TRP A 1 211 ? 139.363 153.698 109.663 1.00 7.55   ? 211 TRP A CZ2   1 
ATOM   590  C CZ3   . TRP A 1 211 ? 139.876 152.574 111.736 1.00 4.86   ? 211 TRP A CZ3   1 
ATOM   591  C CH2   . TRP A 1 211 ? 140.129 153.572 110.788 1.00 6.79   ? 211 TRP A CH2   1 
ATOM   592  N N     . ILE A 1 212 ? 135.765 151.869 113.464 1.00 3.36   ? 212 ILE A N     1 
ATOM   593  C CA    . ILE A 1 212 ? 136.499 152.292 114.653 1.00 6.60   ? 212 ILE A CA    1 
ATOM   594  C C     . ILE A 1 212 ? 136.063 151.487 115.872 1.00 5.65   ? 212 ILE A C     1 
ATOM   595  O O     . ILE A 1 212 ? 136.863 151.252 116.788 1.00 6.15   ? 212 ILE A O     1 
ATOM   596  C CB    . ILE A 1 212 ? 136.340 153.810 114.869 1.00 7.01   ? 212 ILE A CB    1 
ATOM   597  C CG1   . ILE A 1 212 ? 137.473 154.347 115.747 1.00 7.86   ? 212 ILE A CG1   1 
ATOM   598  C CG2   . ILE A 1 212 ? 134.979 154.149 115.462 1.00 4.68   ? 212 ILE A CG2   1 
ATOM   599  C CD1   . ILE A 1 212 ? 138.836 154.265 115.097 1.00 5.99   ? 212 ILE A CD1   1 
ATOM   600  N N     . HIS A 1 213 ? 134.809 151.027 115.898 1.00 5.65   ? 213 HIS A N     1 
ATOM   601  C CA    . HIS A 1 213 ? 134.310 150.230 117.012 1.00 0.39   ? 213 HIS A CA    1 
ATOM   602  C C     . HIS A 1 213 ? 135.046 148.908 117.162 1.00 3.41   ? 213 HIS A C     1 
ATOM   603  O O     . HIS A 1 213 ? 134.951 148.283 118.223 1.00 5.24   ? 213 HIS A O     1 
ATOM   604  C CB    . HIS A 1 213 ? 132.813 149.970 116.842 1.00 6.69   ? 213 HIS A CB    1 
ATOM   605  C CG    . HIS A 1 213 ? 132.430 149.529 115.464 1.00 6.34   ? 213 HIS A CG    1 
ATOM   606  N ND1   . HIS A 1 213 ? 132.747 148.284 114.965 1.00 2.48   ? 213 HIS A ND1   1 
ATOM   607  C CD2   . HIS A 1 213 ? 131.760 150.170 114.477 1.00 3.85   ? 213 HIS A CD2   1 
ATOM   608  C CE1   . HIS A 1 213 ? 132.287 148.176 113.732 1.00 4.34   ? 213 HIS A CE1   1 
ATOM   609  N NE2   . HIS A 1 213 ? 131.685 149.307 113.411 1.00 4.53   ? 213 HIS A NE2   1 
ATOM   610  N N     . CYS A 1 214 ? 135.767 148.466 116.128 1.00 5.62   ? 214 CYS A N     1 
ATOM   611  C CA    . CYS A 1 214 ? 136.599 147.278 116.247 1.00 0.00   ? 214 CYS A CA    1 
ATOM   612  C C     . CYS A 1 214 ? 137.729 147.467 117.249 1.00 1.67   ? 214 CYS A C     1 
ATOM   613  O O     . CYS A 1 214 ? 138.233 146.478 117.789 1.00 4.91   ? 214 CYS A O     1 
ATOM   614  C CB    . CYS A 1 214 ? 137.178 146.903 114.882 1.00 0.00   ? 214 CYS A CB    1 
ATOM   615  S SG    . CYS A 1 214 ? 135.946 146.652 113.586 1.00 9.12   ? 214 CYS A SG    1 
ATOM   616  N N     . PHE A 1 215 ? 138.131 148.711 117.513 1.00 7.31   ? 215 PHE A N     1 
ATOM   617  C CA    . PHE A 1 215 ? 139.229 149.007 118.425 1.00 1.34   ? 215 PHE A CA    1 
ATOM   618  C C     . PHE A 1 215 ? 138.739 149.490 119.784 1.00 5.43   ? 215 PHE A C     1 
ATOM   619  O O     . PHE A 1 215 ? 139.438 150.248 120.462 1.00 13.20  ? 215 PHE A O     1 
ATOM   620  C CB    . PHE A 1 215 ? 140.166 150.039 117.800 1.00 1.27   ? 215 PHE A CB    1 
ATOM   621  C CG    . PHE A 1 215 ? 140.782 149.589 116.509 1.00 4.47   ? 215 PHE A CG    1 
ATOM   622  C CD1   . PHE A 1 215 ? 141.900 148.774 116.508 1.00 5.36   ? 215 PHE A CD1   1 
ATOM   623  C CD2   . PHE A 1 215 ? 140.240 149.975 115.296 1.00 5.62   ? 215 PHE A CD2   1 
ATOM   624  C CE1   . PHE A 1 215 ? 142.468 148.356 115.322 1.00 0.82   ? 215 PHE A CE1   1 
ATOM   625  C CE2   . PHE A 1 215 ? 140.803 149.560 114.107 1.00 5.53   ? 215 PHE A CE2   1 
ATOM   626  C CZ    . PHE A 1 215 ? 141.918 148.749 114.121 1.00 3.04   ? 215 PHE A CZ    1 
ATOM   627  N N     . GLU A 1 216 ? 137.544 149.062 120.197 1.00 3.37   ? 216 GLU A N     1 
ATOM   628  C CA    . GLU A 1 216 ? 137.001 149.502 121.478 1.00 1.20   ? 216 GLU A CA    1 
ATOM   629  C C     . GLU A 1 216 ? 137.848 149.004 122.643 1.00 9.56   ? 216 GLU A C     1 
ATOM   630  O O     . GLU A 1 216 ? 138.077 149.737 123.612 1.00 14.83  ? 216 GLU A O     1 
ATOM   631  C CB    . GLU A 1 216 ? 135.556 149.024 121.621 1.00 3.27   ? 216 GLU A CB    1 
ATOM   632  C CG    . GLU A 1 216 ? 134.879 149.472 122.904 1.00 6.73   ? 216 GLU A CG    1 
ATOM   633  C CD    . GLU A 1 216 ? 133.444 148.996 122.999 1.00 9.63   ? 216 GLU A CD    1 
ATOM   634  O OE1   . GLU A 1 216 ? 132.985 148.299 122.071 1.00 9.40   ? 216 GLU A OE1   1 
ATOM   635  O OE2   . GLU A 1 216 ? 132.775 149.321 124.002 1.00 13.41  ? 216 GLU A OE2   1 
ATOM   636  N N     . GLY A 1 217 ? 138.322 147.766 122.568 1.00 5.23   ? 217 GLY A N     1 
ATOM   637  C CA    . GLY A 1 217 ? 139.041 147.132 123.650 1.00 4.45   ? 217 GLY A CA    1 
ATOM   638  C C     . GLY A 1 217 ? 140.542 147.321 123.660 1.00 7.73   ? 217 GLY A C     1 
ATOM   639  O O     . GLY A 1 217 ? 141.222 146.655 124.447 1.00 10.43  ? 217 GLY A O     1 
ATOM   640  N N     . VAL A 1 218 ? 141.087 148.194 122.811 1.00 8.24   ? 218 VAL A N     1 
ATOM   641  C CA    . VAL A 1 218 ? 142.529 148.403 122.789 1.00 4.48   ? 218 VAL A CA    1 
ATOM   642  C C     . VAL A 1 218 ? 142.982 149.012 124.110 1.00 6.06   ? 218 VAL A C     1 
ATOM   643  O O     . VAL A 1 218 ? 142.246 149.761 124.766 1.00 8.96   ? 218 VAL A O     1 
ATOM   644  C CB    . VAL A 1 218 ? 142.946 149.287 121.599 1.00 2.01   ? 218 VAL A CB    1 
ATOM   645  C CG1   . VAL A 1 218 ? 142.574 148.620 120.286 1.00 7.41   ? 218 VAL A CG1   1 
ATOM   646  C CG2   . VAL A 1 218 ? 142.318 150.668 121.708 1.00 0.89   ? 218 VAL A CG2   1 
ATOM   647  N N     . THR A 1 219 ? 144.207 148.669 124.518 1.00 6.26   ? 219 THR A N     1 
ATOM   648  C CA    . THR A 1 219 ? 144.729 149.180 125.780 1.00 2.78   ? 219 THR A CA    1 
ATOM   649  C C     . THR A 1 219 ? 144.904 150.692 125.736 1.00 5.60   ? 219 THR A C     1 
ATOM   650  O O     . THR A 1 219 ? 144.582 151.388 126.707 1.00 6.60   ? 219 THR A O     1 
ATOM   651  C CB    . THR A 1 219 ? 146.053 148.495 126.124 1.00 5.05   ? 219 THR A CB    1 
ATOM   652  O OG1   . THR A 1 219 ? 145.879 147.074 126.088 1.00 10.08  ? 219 THR A OG1   1 
ATOM   653  C CG2   . THR A 1 219 ? 146.522 148.907 127.510 1.00 8.07   ? 219 THR A CG2   1 
ATOM   654  N N     . ALA A 1 220 ? 145.401 151.225 124.621 1.00 7.16   ? 220 ALA A N     1 
ATOM   655  C CA    . ALA A 1 220 ? 145.605 152.666 124.540 1.00 0.73   ? 220 ALA A CA    1 
ATOM   656  C C     . ALA A 1 220 ? 145.596 153.109 123.085 1.00 1.56   ? 220 ALA A C     1 
ATOM   657  O O     . ALA A 1 220 ? 145.680 152.293 122.163 1.00 4.10   ? 220 ALA A O     1 
ATOM   658  C CB    . ALA A 1 220 ? 146.911 153.088 125.219 1.00 2.25   ? 220 ALA A CB    1 
ATOM   659  N N     . ILE A 1 221 ? 145.484 154.421 122.895 1.00 1.97   ? 221 ILE A N     1 
ATOM   660  C CA    . ILE A 1 221 ? 145.538 155.039 121.576 1.00 0.76   ? 221 ILE A CA    1 
ATOM   661  C C     . ILE A 1 221 ? 146.748 155.959 121.540 1.00 0.00   ? 221 ILE A C     1 
ATOM   662  O O     . ILE A 1 221 ? 146.828 156.917 122.316 1.00 7.70   ? 221 ILE A O     1 
ATOM   663  C CB    . ILE A 1 221 ? 144.255 155.819 121.258 1.00 1.62   ? 221 ILE A CB    1 
ATOM   664  C CG1   . ILE A 1 221 ? 143.071 154.868 121.092 1.00 6.19   ? 221 ILE A CG1   1 
ATOM   665  C CG2   . ILE A 1 221 ? 144.444 156.666 120.009 1.00 2.54   ? 221 ILE A CG2   1 
ATOM   666  C CD1   . ILE A 1 221 ? 141.750 155.487 121.472 1.00 4.40   ? 221 ILE A CD1   1 
ATOM   667  N N     . ILE A 1 222 ? 147.680 155.682 120.637 1.00 1.40   ? 222 ILE A N     1 
ATOM   668  C CA    . ILE A 1 222 ? 148.856 156.523 120.449 1.00 2.74   ? 222 ILE A CA    1 
ATOM   669  C C     . ILE A 1 222 ? 148.546 157.499 119.322 1.00 2.95   ? 222 ILE A C     1 
ATOM   670  O O     . ILE A 1 222 ? 148.491 157.114 118.152 1.00 6.29   ? 222 ILE A O     1 
ATOM   671  C CB    . ILE A 1 222 ? 150.103 155.688 120.137 1.00 5.03   ? 222 ILE A CB    1 
ATOM   672  C CG1   . ILE A 1 222 ? 150.464 154.799 121.328 1.00 8.07   ? 222 ILE A CG1   1 
ATOM   673  C CG2   . ILE A 1 222 ? 151.269 156.592 119.775 1.00 6.79   ? 222 ILE A CG2   1 
ATOM   674  C CD1   . ILE A 1 222 ? 151.760 154.044 121.149 1.00 12.04  ? 222 ILE A CD1   1 
ATOM   675  N N     . PHE A 1 223 ? 148.346 158.766 119.670 1.00 6.95   ? 223 PHE A N     1 
ATOM   676  C CA    . PHE A 1 223 ? 147.998 159.799 118.704 1.00 5.04   ? 223 PHE A CA    1 
ATOM   677  C C     . PHE A 1 223 ? 149.226 160.660 118.439 1.00 8.89   ? 223 PHE A C     1 
ATOM   678  O O     . PHE A 1 223 ? 149.769 161.271 119.363 1.00 17.40  ? 223 PHE A O     1 
ATOM   679  C CB    . PHE A 1 223 ? 146.839 160.653 119.214 1.00 3.84   ? 223 PHE A CB    1 
ATOM   680  C CG    . PHE A 1 223 ? 146.066 161.339 118.126 1.00 12.97  ? 223 PHE A CG    1 
ATOM   681  C CD1   . PHE A 1 223 ? 146.552 162.490 117.532 1.00 13.99  ? 223 PHE A CD1   1 
ATOM   682  C CD2   . PHE A 1 223 ? 144.852 160.831 117.697 1.00 12.92  ? 223 PHE A CD2   1 
ATOM   683  C CE1   . PHE A 1 223 ? 145.843 163.122 116.530 1.00 9.25   ? 223 PHE A CE1   1 
ATOM   684  C CE2   . PHE A 1 223 ? 144.139 161.458 116.695 1.00 14.45  ? 223 PHE A CE2   1 
ATOM   685  C CZ    . PHE A 1 223 ? 144.636 162.605 116.112 1.00 11.80  ? 223 PHE A CZ    1 
ATOM   686  N N     . CYS A 1 224 ? 149.651 160.716 117.180 1.00 7.97   ? 224 CYS A N     1 
ATOM   687  C CA    . CYS A 1 224 ? 150.841 161.459 116.788 1.00 12.25  ? 224 CYS A CA    1 
ATOM   688  C C     . CYS A 1 224 ? 150.436 162.764 116.117 1.00 17.68  ? 224 CYS A C     1 
ATOM   689  O O     . CYS A 1 224 ? 149.623 162.764 115.187 1.00 23.73  ? 224 CYS A O     1 
ATOM   690  C CB    . CYS A 1 224 ? 151.715 160.630 115.846 1.00 16.34  ? 224 CYS A CB    1 
ATOM   691  S SG    . CYS A 1 224 ? 152.358 159.106 116.572 1.00 32.90  ? 224 CYS A SG    1 
ATOM   692  N N     . VAL A 1 225 ? 151.004 163.871 116.591 1.00 18.22  ? 225 VAL A N     1 
ATOM   693  C CA    . VAL A 1 225 ? 150.740 165.195 116.042 1.00 16.11  ? 225 VAL A CA    1 
ATOM   694  C C     . VAL A 1 225 ? 152.073 165.857 115.730 1.00 20.09  ? 225 VAL A C     1 
ATOM   695  O O     . VAL A 1 225 ? 152.962 165.902 116.587 1.00 21.15  ? 225 VAL A O     1 
ATOM   696  C CB    . VAL A 1 225 ? 149.921 166.067 117.012 1.00 16.62  ? 225 VAL A CB    1 
ATOM   697  C CG1   . VAL A 1 225 ? 149.824 167.490 116.490 1.00 20.23  ? 225 VAL A CG1   1 
ATOM   698  C CG2   . VAL A 1 225 ? 148.537 165.475 117.221 1.00 19.25  ? 225 VAL A CG2   1 
ATOM   699  N N     . ALA A 1 226 ? 152.212 166.372 114.512 1.00 26.28  ? 226 ALA A N     1 
ATOM   700  C CA    . ALA A 1 226 ? 153.426 167.074 114.119 1.00 25.21  ? 226 ALA A CA    1 
ATOM   701  C C     . ALA A 1 226 ? 153.382 168.501 114.652 1.00 29.17  ? 226 ALA A C     1 
ATOM   702  O O     . ALA A 1 226 ? 152.465 169.262 114.327 1.00 33.70  ? 226 ALA A O     1 
ATOM   703  C CB    . ALA A 1 226 ? 153.580 167.068 112.600 1.00 28.57  ? 226 ALA A CB    1 
ATOM   704  N N     . LEU A 1 227 ? 154.370 168.860 115.475 1.00 27.37  ? 227 LEU A N     1 
ATOM   705  C CA    . LEU A 1 227 ? 154.415 170.209 116.029 1.00 27.74  ? 227 LEU A CA    1 
ATOM   706  C C     . LEU A 1 227 ? 154.684 171.252 114.953 1.00 33.02  ? 227 LEU A C     1 
ATOM   707  O O     . LEU A 1 227 ? 154.178 172.377 115.042 1.00 33.23  ? 227 LEU A O     1 
ATOM   708  C CB    . LEU A 1 227 ? 155.478 170.294 117.124 1.00 31.04  ? 227 LEU A CB    1 
ATOM   709  C CG    . LEU A 1 227 ? 155.099 169.738 118.498 1.00 28.95  ? 227 LEU A CG    1 
ATOM   710  C CD1   . LEU A 1 227 ? 156.312 169.699 119.411 1.00 27.26  ? 227 LEU A CD1   1 
ATOM   711  C CD2   . LEU A 1 227 ? 153.983 170.560 119.120 1.00 29.53  ? 227 LEU A CD2   1 
ATOM   712  N N     . SER A 1 228 ? 155.473 170.904 113.935 1.00 33.98  ? 228 SER A N     1 
ATOM   713  C CA    . SER A 1 228 ? 155.786 171.834 112.858 1.00 33.90  ? 228 SER A CA    1 
ATOM   714  C C     . SER A 1 228 ? 154.610 172.074 111.921 1.00 35.10  ? 228 SER A C     1 
ATOM   715  O O     . SER A 1 228 ? 154.692 172.965 111.070 1.00 40.30  ? 228 SER A O     1 
ATOM   716  C CB    . SER A 1 228 ? 156.986 171.323 112.060 1.00 34.55  ? 228 SER A CB    1 
ATOM   717  O OG    . SER A 1 228 ? 156.742 170.023 111.553 1.00 31.56  ? 228 SER A OG    1 
ATOM   718  N N     . ASP A 1 229 ? 153.526 171.308 112.054 1.00 33.26  ? 229 ASP A N     1 
ATOM   719  C CA    . ASP A 1 229 ? 152.375 171.451 111.171 1.00 33.50  ? 229 ASP A CA    1 
ATOM   720  C C     . ASP A 1 229 ? 151.558 172.706 111.454 1.00 35.70  ? 229 ASP A C     1 
ATOM   721  O O     . ASP A 1 229 ? 150.629 172.998 110.694 1.00 38.33  ? 229 ASP A O     1 
ATOM   722  C CB    . ASP A 1 229 ? 151.476 170.218 111.280 1.00 33.98  ? 229 ASP A CB    1 
ATOM   723  N N     . TYR A 1 230 ? 151.871 173.443 112.524 1.00 35.28  ? 230 TYR A N     1 
ATOM   724  C CA    . TYR A 1 230 ? 151.099 174.637 112.854 1.00 37.39  ? 230 TYR A CA    1 
ATOM   725  C C     . TYR A 1 230 ? 151.200 175.698 111.766 1.00 40.54  ? 230 TYR A C     1 
ATOM   726  O O     . TYR A 1 230 ? 150.261 176.479 111.573 1.00 41.09  ? 230 TYR A O     1 
ATOM   727  C CB    . TYR A 1 230 ? 151.561 175.207 114.196 1.00 35.34  ? 230 TYR A CB    1 
ATOM   728  C CG    . TYR A 1 230 ? 152.848 175.998 114.120 1.00 35.10  ? 230 TYR A CG    1 
ATOM   729  C CD1   . TYR A 1 230 ? 154.066 175.363 113.918 1.00 36.40  ? 230 TYR A CD1   1 
ATOM   730  C CD2   . TYR A 1 230 ? 152.845 177.380 114.253 1.00 35.91  ? 230 TYR A CD2   1 
ATOM   731  C CE1   . TYR A 1 230 ? 155.244 176.081 113.849 1.00 38.55  ? 230 TYR A CE1   1 
ATOM   732  C CE2   . TYR A 1 230 ? 154.018 178.107 114.186 1.00 38.10  ? 230 TYR A CE2   1 
ATOM   733  C CZ    . TYR A 1 230 ? 155.214 177.452 113.984 1.00 39.18  ? 230 TYR A CZ    1 
ATOM   734  O OH    . TYR A 1 230 ? 156.385 178.171 113.916 1.00 39.20  ? 230 TYR A OH    1 
ATOM   735  N N     . ASP A 1 231 ? 152.319 175.744 111.047 1.00 42.65  ? 231 ASP A N     1 
ATOM   736  C CA    . ASP A 1 231 ? 152.515 176.710 109.975 1.00 41.13  ? 231 ASP A CA    1 
ATOM   737  C C     . ASP A 1 231 ? 152.106 176.173 108.610 1.00 39.68  ? 231 ASP A C     1 
ATOM   738  O O     . ASP A 1 231 ? 152.241 176.891 107.614 1.00 41.38  ? 231 ASP A O     1 
ATOM   739  C CB    . ASP A 1 231 ? 153.979 177.160 109.933 1.00 38.18  ? 231 ASP A CB    1 
ATOM   740  N N     . LEU A 1 232 ? 151.613 174.942 108.540 1.00 35.23  ? 232 LEU A N     1 
ATOM   741  C CA    . LEU A 1 232 ? 151.217 174.317 107.288 1.00 36.70  ? 232 LEU A CA    1 
ATOM   742  C C     . LEU A 1 232 ? 149.699 174.233 107.195 1.00 37.55  ? 232 LEU A C     1 
ATOM   743  O O     . LEU A 1 232 ? 148.984 174.325 108.196 1.00 36.40  ? 232 LEU A O     1 
ATOM   744  C CB    . LEU A 1 232 ? 151.828 172.918 107.154 1.00 38.40  ? 232 LEU A CB    1 
ATOM   745  C CG    . LEU A 1 232 ? 153.160 172.803 106.409 1.00 39.08  ? 232 LEU A CG    1 
ATOM   746  C CD1   . LEU A 1 232 ? 154.252 173.601 107.105 1.00 37.86  ? 232 LEU A CD1   1 
ATOM   747  C CD2   . LEU A 1 232 ? 153.566 171.345 106.266 1.00 36.21  ? 232 LEU A CD2   1 
ATOM   748  N N     . VAL A 1 233 ? 149.213 174.055 105.966 1.00 38.55  ? 233 VAL A N     1 
ATOM   749  C CA    . VAL A 1 233 ? 147.789 173.939 105.692 1.00 40.62  ? 233 VAL A CA    1 
ATOM   750  C C     . VAL A 1 233 ? 147.564 172.767 104.747 1.00 40.56  ? 233 VAL A C     1 
ATOM   751  O O     . VAL A 1 233 ? 148.470 172.322 104.041 1.00 40.48  ? 233 VAL A O     1 
ATOM   752  C CB    . VAL A 1 233 ? 147.199 175.234 105.093 1.00 38.08  ? 233 VAL A CB    1 
ATOM   753  N N     . LEU A 1 234 ? 146.332 172.268 104.745 1.00 42.05  ? 234 LEU A N     1 
ATOM   754  C CA    . LEU A 1 234 ? 145.961 171.149 103.886 1.00 42.03  ? 234 LEU A CA    1 
ATOM   755  C C     . LEU A 1 234 ? 145.666 171.620 102.466 1.00 41.21  ? 234 LEU A C     1 
ATOM   756  O O     . LEU A 1 234 ? 145.642 170.822 101.529 1.00 41.69  ? 234 LEU A O     1 
ATOM   757  C CB    . LEU A 1 234 ? 144.748 170.411 104.458 1.00 41.70  ? 234 LEU A CB    1 
ATOM   758  C CG    . LEU A 1 234 ? 145.030 169.151 105.281 1.00 41.57  ? 234 LEU A CG    1 
ATOM   759  C CD1   . LEU A 1 234 ? 145.927 169.462 106.467 1.00 39.05  ? 234 LEU A CD1   1 
ATOM   760  C CD2   . LEU A 1 234 ? 143.729 168.513 105.742 1.00 41.60  ? 234 LEU A CD2   1 
ATOM   761  N N     . MET A 1 240 ? 142.294 174.871 105.273 1.00 49.37  ? 240 MET A N     1 
ATOM   762  C CA    . MET A 1 240 ? 142.283 174.233 106.585 1.00 50.27  ? 240 MET A CA    1 
ATOM   763  C C     . MET A 1 240 ? 143.702 174.022 107.101 1.00 48.85  ? 240 MET A C     1 
ATOM   764  O O     . MET A 1 240 ? 144.511 173.347 106.463 1.00 46.90  ? 240 MET A O     1 
ATOM   765  C CB    . MET A 1 240 ? 141.539 172.898 106.526 1.00 48.52  ? 240 MET A CB    1 
ATOM   766  C CG    . MET A 1 240 ? 141.645 172.072 107.797 1.00 51.14  ? 240 MET A CG    1 
ATOM   767  S SD    . MET A 1 240 ? 141.137 172.987 109.265 1.00 57.73  ? 240 MET A SD    1 
ATOM   768  C CE    . MET A 1 240 ? 139.386 173.190 108.949 1.00 48.62  ? 240 MET A CE    1 
ATOM   769  N N     . ASN A 1 241 ? 143.998 174.607 108.259 1.00 42.87  ? 241 ASN A N     1 
ATOM   770  C CA    . ASN A 1 241 ? 145.321 174.472 108.851 1.00 41.78  ? 241 ASN A CA    1 
ATOM   771  C C     . ASN A 1 241 ? 145.564 173.033 109.292 1.00 44.17  ? 241 ASN A C     1 
ATOM   772  O O     . ASN A 1 241 ? 144.650 172.344 109.754 1.00 42.97  ? 241 ASN A O     1 
ATOM   773  C CB    . ASN A 1 241 ? 145.470 175.422 110.038 1.00 40.25  ? 241 ASN A CB    1 
ATOM   774  C CG    . ASN A 1 241 ? 146.885 175.459 110.583 1.00 44.14  ? 241 ASN A CG    1 
ATOM   775  O OD1   . ASN A 1 241 ? 147.318 174.542 111.280 1.00 44.06  ? 241 ASN A OD1   1 
ATOM   776  N ND2   . ASN A 1 241 ? 147.613 176.523 110.266 1.00 42.69  ? 241 ASN A ND2   1 
ATOM   777  N N     . ARG A 1 242 ? 146.810 172.579 109.139 1.00 41.64  ? 242 ARG A N     1 
ATOM   778  C CA    . ARG A 1 242 ? 147.150 171.208 109.508 1.00 40.63  ? 242 ARG A CA    1 
ATOM   779  C C     . ARG A 1 242 ? 146.979 170.977 111.005 1.00 36.38  ? 242 ARG A C     1 
ATOM   780  O O     . ARG A 1 242 ? 146.466 169.932 111.424 1.00 35.00  ? 242 ARG A O     1 
ATOM   781  C CB    . ARG A 1 242 ? 148.581 170.888 109.075 1.00 33.94  ? 242 ARG A CB    1 
ATOM   782  N N     . MET A 1 243 ? 147.408 171.938 111.827 1.00 33.78  ? 243 MET A N     1 
ATOM   783  C CA    . MET A 1 243 ? 147.260 171.792 113.272 1.00 34.18  ? 243 MET A CA    1 
ATOM   784  C C     . MET A 1 243 ? 145.792 171.773 113.679 1.00 35.00  ? 243 MET A C     1 
ATOM   785  O O     . MET A 1 243 ? 145.400 171.013 114.571 1.00 36.82  ? 243 MET A O     1 
ATOM   786  C CB    . MET A 1 243 ? 148.006 172.914 113.993 1.00 36.64  ? 243 MET A CB    1 
ATOM   787  C CG    . MET A 1 243 ? 148.056 172.755 115.502 1.00 35.82  ? 243 MET A CG    1 
ATOM   788  S SD    . MET A 1 243 ? 148.946 171.273 116.013 1.00 41.49  ? 243 MET A SD    1 
ATOM   789  C CE    . MET A 1 243 ? 150.630 171.740 115.625 1.00 36.28  ? 243 MET A CE    1 
ATOM   790  N N     . HIS A 1 244 ? 144.966 172.605 113.040 1.00 37.22  ? 244 HIS A N     1 
ATOM   791  C CA    . HIS A 1 244 ? 143.537 172.598 113.339 1.00 37.91  ? 244 HIS A CA    1 
ATOM   792  C C     . HIS A 1 244 ? 142.897 171.272 112.947 1.00 35.20  ? 244 HIS A C     1 
ATOM   793  O O     . HIS A 1 244 ? 142.044 170.748 113.673 1.00 34.56  ? 244 HIS A O     1 
ATOM   794  C CB    . HIS A 1 244 ? 142.848 173.762 112.629 1.00 39.47  ? 244 HIS A CB    1 
ATOM   795  C CG    . HIS A 1 244 ? 142.994 175.073 113.337 1.00 39.10  ? 244 HIS A CG    1 
ATOM   796  N ND1   . HIS A 1 244 ? 142.149 175.470 114.350 1.00 39.85  ? 244 HIS A ND1   1 
ATOM   797  C CD2   . HIS A 1 244 ? 143.890 176.076 113.180 1.00 38.35  ? 244 HIS A CD2   1 
ATOM   798  C CE1   . HIS A 1 244 ? 142.516 176.661 114.786 1.00 39.90  ? 244 HIS A CE1   1 
ATOM   799  N NE2   . HIS A 1 244 ? 143.570 177.052 114.093 1.00 40.91  ? 244 HIS A NE2   1 
ATOM   800  N N     . GLU A 1 245 ? 143.292 170.717 111.799 1.00 31.17  ? 245 GLU A N     1 
ATOM   801  C CA    . GLU A 1 245 ? 142.784 169.409 111.397 1.00 33.41  ? 245 GLU A CA    1 
ATOM   802  C C     . GLU A 1 245 ? 143.214 168.327 112.379 1.00 32.22  ? 245 GLU A C     1 
ATOM   803  O O     . GLU A 1 245 ? 142.427 167.432 112.715 1.00 32.47  ? 245 GLU A O     1 
ATOM   804  C CB    . GLU A 1 245 ? 143.260 169.073 109.984 1.00 33.05  ? 245 GLU A CB    1 
ATOM   805  N N     . SER A 1 246 ? 144.464 168.390 112.846 1.00 29.34  ? 246 SER A N     1 
ATOM   806  C CA    . SER A 1 246 ? 144.933 167.430 113.839 1.00 25.62  ? 246 SER A CA    1 
ATOM   807  C C     . SER A 1 246 ? 144.141 167.549 115.134 1.00 22.23  ? 246 SER A C     1 
ATOM   808  O O     . SER A 1 246 ? 143.787 166.538 115.748 1.00 20.79  ? 246 SER A O     1 
ATOM   809  C CB    . SER A 1 246 ? 146.425 167.635 114.104 1.00 22.91  ? 246 SER A CB    1 
ATOM   810  O OG    . SER A 1 246 ? 147.185 167.451 112.924 1.00 26.65  ? 246 SER A OG    1 
ATOM   811  N N     . MET A 1 247 ? 143.855 168.780 115.563 1.00 25.07  ? 247 MET A N     1 
ATOM   812  C CA    . MET A 1 247 ? 143.058 168.980 116.770 1.00 24.15  ? 247 MET A CA    1 
ATOM   813  C C     . MET A 1 247 ? 141.645 168.439 116.595 1.00 22.49  ? 247 MET A C     1 
ATOM   814  O O     . MET A 1 247 ? 141.086 167.832 117.515 1.00 27.29  ? 247 MET A O     1 
ATOM   815  C CB    . MET A 1 247 ? 143.018 170.462 117.138 1.00 25.82  ? 247 MET A CB    1 
ATOM   816  C CG    . MET A 1 247 ? 144.334 171.018 117.649 1.00 27.06  ? 247 MET A CG    1 
ATOM   817  S SD    . MET A 1 247 ? 144.093 172.396 118.785 1.00 37.37  ? 247 MET A SD    1 
ATOM   818  C CE    . MET A 1 247 ? 142.942 173.402 117.852 1.00 29.14  ? 247 MET A CE    1 
ATOM   819  N N     . LYS A 1 248 ? 141.045 168.660 115.423 1.00 23.47  ? 248 LYS A N     1 
ATOM   820  C CA    . LYS A 1 248 ? 139.704 168.140 115.168 1.00 23.59  ? 248 LYS A CA    1 
ATOM   821  C C     . LYS A 1 248 ? 139.691 166.616 115.188 1.00 23.30  ? 248 LYS A C     1 
ATOM   822  O O     . LYS A 1 248 ? 138.782 166.002 115.761 1.00 23.70  ? 248 LYS A O     1 
ATOM   823  C CB    . LYS A 1 248 ? 139.183 168.665 113.831 1.00 19.70  ? 248 LYS A CB    1 
ATOM   824  N N     . LEU A 1 249 ? 140.692 165.989 114.567 1.00 21.02  ? 249 LEU A N     1 
ATOM   825  C CA    . LEU A 1 249 ? 140.771 164.532 114.582 1.00 16.48  ? 249 LEU A CA    1 
ATOM   826  C C     . LEU A 1 249 ? 140.991 164.007 115.995 1.00 19.33  ? 249 LEU A C     1 
ATOM   827  O O     . LEU A 1 249 ? 140.410 162.987 116.385 1.00 17.67  ? 249 LEU A O     1 
ATOM   828  C CB    . LEU A 1 249 ? 141.885 164.055 113.651 1.00 17.87  ? 249 LEU A CB    1 
ATOM   829  C CG    . LEU A 1 249 ? 142.066 162.539 113.561 1.00 19.14  ? 249 LEU A CG    1 
ATOM   830  C CD1   . LEU A 1 249 ? 140.775 161.873 113.115 1.00 21.95  ? 249 LEU A CD1   1 
ATOM   831  C CD2   . LEU A 1 249 ? 143.204 162.192 112.618 1.00 15.97  ? 249 LEU A CD2   1 
ATOM   832  N N     . PHE A 1 250 ? 141.831 164.691 116.777 1.00 18.78  ? 250 PHE A N     1 
ATOM   833  C CA    . PHE A 1 250 ? 142.047 164.294 118.163 1.00 12.44  ? 250 PHE A CA    1 
ATOM   834  C C     . PHE A 1 250 ? 140.761 164.396 118.970 1.00 13.94  ? 250 PHE A C     1 
ATOM   835  O O     . PHE A 1 250 ? 140.454 163.510 119.773 1.00 23.86  ? 250 PHE A O     1 
ATOM   836  C CB    . PHE A 1 250 ? 143.145 165.156 118.788 1.00 12.43  ? 250 PHE A CB    1 
ATOM   837  C CG    . PHE A 1 250 ? 143.488 164.776 120.201 1.00 17.08  ? 250 PHE A CG    1 
ATOM   838  C CD1   . PHE A 1 250 ? 144.426 163.792 120.459 1.00 18.19  ? 250 PHE A CD1   1 
ATOM   839  C CD2   . PHE A 1 250 ? 142.881 165.412 121.271 1.00 18.28  ? 250 PHE A CD2   1 
ATOM   840  C CE1   . PHE A 1 250 ? 144.746 163.443 121.756 1.00 15.46  ? 250 PHE A CE1   1 
ATOM   841  C CE2   . PHE A 1 250 ? 143.196 165.067 122.570 1.00 15.19  ? 250 PHE A CE2   1 
ATOM   842  C CZ    . PHE A 1 250 ? 144.130 164.082 122.813 1.00 14.51  ? 250 PHE A CZ    1 
ATOM   843  N N     . ASP A 1 251 ? 139.999 165.473 118.771 1.00 16.74  ? 251 ASP A N     1 
ATOM   844  C CA    . ASP A 1 251 ? 138.723 165.622 119.463 1.00 17.87  ? 251 ASP A CA    1 
ATOM   845  C C     . ASP A 1 251 ? 137.759 164.509 119.077 1.00 19.36  ? 251 ASP A C     1 
ATOM   846  O O     . ASP A 1 251 ? 137.097 163.921 119.941 1.00 20.35  ? 251 ASP A O     1 
ATOM   847  C CB    . ASP A 1 251 ? 138.123 166.994 119.149 1.00 16.57  ? 251 ASP A CB    1 
ATOM   848  C CG    . ASP A 1 251 ? 137.011 167.386 120.106 1.00 22.03  ? 251 ASP A CG    1 
ATOM   849  O OD1   . ASP A 1 251 ? 136.081 166.581 120.318 1.00 24.15  ? 251 ASP A OD1   1 
ATOM   850  O OD2   . ASP A 1 251 ? 137.067 168.509 120.649 1.00 23.65  ? 251 ASP A OD2   1 
ATOM   851  N N     . SER A 1 252 ? 137.678 164.197 117.781 1.00 17.83  ? 252 SER A N     1 
ATOM   852  C CA    . SER A 1 252 ? 136.776 163.144 117.326 1.00 18.64  ? 252 SER A CA    1 
ATOM   853  C C     . SER A 1 252 ? 137.166 161.790 117.906 1.00 18.38  ? 252 SER A C     1 
ATOM   854  O O     . SER A 1 252 ? 136.300 161.006 118.311 1.00 16.45  ? 252 SER A O     1 
ATOM   855  C CB    . SER A 1 252 ? 136.765 163.089 115.798 1.00 17.78  ? 252 SER A CB    1 
ATOM   856  O OG    . SER A 1 252 ? 135.899 162.069 115.331 1.00 18.30  ? 252 SER A OG    1 
ATOM   857  N N     . ILE A 1 253 ? 138.467 161.496 117.953 1.00 18.60  ? 253 ILE A N     1 
ATOM   858  C CA    . ILE A 1 253 ? 138.919 160.210 118.474 1.00 17.53  ? 253 ILE A CA    1 
ATOM   859  C C     . ILE A 1 253 ? 138.707 160.132 119.981 1.00 20.41  ? 253 ILE A C     1 
ATOM   860  O O     . ILE A 1 253 ? 138.283 159.098 120.510 1.00 21.50  ? 253 ILE A O     1 
ATOM   861  C CB    . ILE A 1 253 ? 140.392 159.975 118.091 1.00 15.84  ? 253 ILE A CB    1 
ATOM   862  C CG1   . ILE A 1 253 ? 140.507 159.649 116.601 1.00 18.19  ? 253 ILE A CG1   1 
ATOM   863  C CG2   . ILE A 1 253 ? 140.998 158.861 118.930 1.00 18.20  ? 253 ILE A CG2   1 
ATOM   864  C CD1   . ILE A 1 253 ? 139.710 158.435 116.180 1.00 15.22  ? 253 ILE A CD1   1 
ATOM   865  N N     . CYS A 1 254 ? 138.988 161.223 120.697 1.00 19.02  ? 254 CYS A N     1 
ATOM   866  C CA    . CYS A 1 254 ? 138.926 161.197 122.153 1.00 12.02  ? 254 CYS A CA    1 
ATOM   867  C C     . CYS A 1 254 ? 137.488 161.175 122.657 1.00 21.03  ? 254 CYS A C     1 
ATOM   868  O O     . CYS A 1 254 ? 137.180 160.481 123.632 1.00 25.76  ? 254 CYS A O     1 
ATOM   869  C CB    . CYS A 1 254 ? 139.674 162.403 122.720 1.00 13.50  ? 254 CYS A CB    1 
ATOM   870  S SG    . CYS A 1 254 ? 139.521 162.623 124.505 1.00 33.27  ? 254 CYS A SG    1 
ATOM   871  N N     . ASN A 1 255 ? 136.594 161.921 122.010 1.00 23.10  ? 255 ASN A N     1 
ATOM   872  C CA    . ASN A 1 255 ? 135.252 162.134 122.531 1.00 22.27  ? 255 ASN A CA    1 
ATOM   873  C C     . ASN A 1 255 ? 134.197 161.251 121.875 1.00 23.21  ? 255 ASN A C     1 
ATOM   874  O O     . ASN A 1 255 ? 133.002 161.483 122.080 1.00 25.58  ? 255 ASN A O     1 
ATOM   875  C CB    . ASN A 1 255 ? 134.865 163.607 122.385 1.00 18.93  ? 255 ASN A CB    1 
ATOM   876  C CG    . ASN A 1 255 ? 135.756 164.523 123.201 1.00 20.13  ? 255 ASN A CG    1 
ATOM   877  O OD1   . ASN A 1 255 ? 135.985 164.288 124.387 1.00 22.97  ? 255 ASN A OD1   1 
ATOM   878  N ND2   . ASN A 1 255 ? 136.265 165.571 122.568 1.00 22.74  ? 255 ASN A ND2   1 
ATOM   879  N N     . ASN A 1 256 ? 134.598 160.250 121.096 1.00 17.57  ? 256 ASN A N     1 
ATOM   880  C CA    . ASN A 1 256 ? 133.609 159.363 120.507 1.00 21.08  ? 256 ASN A CA    1 
ATOM   881  C C     . ASN A 1 256 ? 133.116 158.350 121.540 1.00 18.92  ? 256 ASN A C     1 
ATOM   882  O O     . ASN A 1 256 ? 133.712 158.158 122.603 1.00 16.47  ? 256 ASN A O     1 
ATOM   883  C CB    . ASN A 1 256 ? 134.172 158.655 119.274 1.00 17.48  ? 256 ASN A CB    1 
ATOM   884  C CG    . ASN A 1 256 ? 135.389 157.811 119.583 1.00 15.42  ? 256 ASN A CG    1 
ATOM   885  O OD1   . ASN A 1 256 ? 135.850 157.750 120.722 1.00 19.80  ? 256 ASN A OD1   1 
ATOM   886  N ND2   . ASN A 1 256 ? 135.916 157.147 118.562 1.00 16.70  ? 256 ASN A ND2   1 
ATOM   887  N N     . LYS A 1 257 ? 132.003 157.693 121.210 1.00 17.98  ? 257 LYS A N     1 
ATOM   888  C CA    . LYS A 1 257 ? 131.354 156.769 122.132 1.00 15.15  ? 257 LYS A CA    1 
ATOM   889  C C     . LYS A 1 257 ? 132.147 155.490 122.365 1.00 15.84  ? 257 LYS A C     1 
ATOM   890  O O     . LYS A 1 257 ? 131.820 154.745 123.295 1.00 14.39  ? 257 LYS A O     1 
ATOM   891  C CB    . LYS A 1 257 ? 129.957 156.419 121.616 1.00 13.85  ? 257 LYS A CB    1 
ATOM   892  C CG    . LYS A 1 257 ? 129.958 155.640 120.311 1.00 11.81  ? 257 LYS A CG    1 
ATOM   893  C CD    . LYS A 1 257 ? 128.545 155.319 119.853 1.00 13.58  ? 257 LYS A CD    1 
ATOM   894  C CE    . LYS A 1 257 ? 127.770 154.572 120.927 1.00 16.00  ? 257 LYS A CE    1 
ATOM   895  N NZ    . LYS A 1 257 ? 128.490 153.355 121.392 1.00 16.85  ? 257 LYS A NZ    1 
ATOM   896  N N     . TRP A 1 258 ? 133.168 155.212 121.555 1.00 15.85  ? 258 TRP A N     1 
ATOM   897  C CA    . TRP A 1 258 ? 133.914 153.967 121.676 1.00 11.31  ? 258 TRP A CA    1 
ATOM   898  C C     . TRP A 1 258 ? 135.178 154.097 122.513 1.00 9.40   ? 258 TRP A C     1 
ATOM   899  O O     . TRP A 1 258 ? 135.699 153.078 122.982 1.00 11.86  ? 258 TRP A O     1 
ATOM   900  C CB    . TRP A 1 258 ? 134.278 153.436 120.286 1.00 9.44   ? 258 TRP A CB    1 
ATOM   901  C CG    . TRP A 1 258 ? 133.099 153.315 119.374 1.00 12.31  ? 258 TRP A CG    1 
ATOM   902  C CD1   . TRP A 1 258 ? 132.859 154.041 118.245 1.00 14.22  ? 258 TRP A CD1   1 
ATOM   903  C CD2   . TRP A 1 258 ? 131.994 152.415 119.515 1.00 10.88  ? 258 TRP A CD2   1 
ATOM   904  N NE1   . TRP A 1 258 ? 131.674 153.648 117.673 1.00 11.00  ? 258 TRP A NE1   1 
ATOM   905  C CE2   . TRP A 1 258 ? 131.123 152.652 118.434 1.00 10.82  ? 258 TRP A CE2   1 
ATOM   906  C CE3   . TRP A 1 258 ? 131.656 151.433 120.451 1.00 8.50   ? 258 TRP A CE3   1 
ATOM   907  C CZ2   . TRP A 1 258 ? 129.937 151.942 118.263 1.00 10.17  ? 258 TRP A CZ2   1 
ATOM   908  C CZ3   . TRP A 1 258 ? 130.479 150.730 120.279 1.00 8.53   ? 258 TRP A CZ3   1 
ATOM   909  C CH2   . TRP A 1 258 ? 129.634 150.988 119.193 1.00 7.87   ? 258 TRP A CH2   1 
ATOM   910  N N     . PHE A 1 259 ? 135.680 155.313 122.718 1.00 12.10  ? 259 PHE A N     1 
ATOM   911  C CA    . PHE A 1 259 ? 136.899 155.511 123.492 1.00 12.57  ? 259 PHE A CA    1 
ATOM   912  C C     . PHE A 1 259 ? 136.630 156.396 124.702 1.00 14.30  ? 259 PHE A C     1 
ATOM   913  O O     . PHE A 1 259 ? 137.382 157.337 124.971 1.00 16.34  ? 259 PHE A O     1 
ATOM   914  C CB    . PHE A 1 259 ? 137.998 156.118 122.619 1.00 8.03   ? 259 PHE A CB    1 
ATOM   915  C CG    . PHE A 1 259 ? 138.288 155.328 121.378 1.00 12.78  ? 259 PHE A CG    1 
ATOM   916  C CD1   . PHE A 1 259 ? 138.445 153.954 121.437 1.00 6.26   ? 259 PHE A CD1   1 
ATOM   917  C CD2   . PHE A 1 259 ? 138.410 155.958 120.152 1.00 15.67  ? 259 PHE A CD2   1 
ATOM   918  C CE1   . PHE A 1 259 ? 138.712 153.225 120.298 1.00 3.54   ? 259 PHE A CE1   1 
ATOM   919  C CE2   . PHE A 1 259 ? 138.677 155.233 119.008 1.00 11.53  ? 259 PHE A CE2   1 
ATOM   920  C CZ    . PHE A 1 259 ? 138.829 153.864 119.082 1.00 7.64   ? 259 PHE A CZ    1 
ATOM   921  N N     . THR A 1 260 ? 135.548 156.103 125.427 1.00 18.68  ? 260 THR A N     1 
ATOM   922  C CA    . THR A 1 260 ? 135.187 156.912 126.587 1.00 18.24  ? 260 THR A CA    1 
ATOM   923  C C     . THR A 1 260 ? 136.259 156.847 127.669 1.00 16.64  ? 260 THR A C     1 
ATOM   924  O O     . THR A 1 260 ? 136.634 157.875 128.244 1.00 20.89  ? 260 THR A O     1 
ATOM   925  C CB    . THR A 1 260 ? 133.837 156.453 127.140 1.00 17.15  ? 260 THR A CB    1 
ATOM   926  O OG1   . THR A 1 260 ? 132.823 156.641 126.146 1.00 22.21  ? 260 THR A OG1   1 
ATOM   927  C CG2   . THR A 1 260 ? 133.469 157.241 128.386 1.00 16.62  ? 260 THR A CG2   1 
ATOM   928  N N     . ASP A 1 261 ? 136.770 155.651 127.955 1.00 11.78  ? 261 ASP A N     1 
ATOM   929  C CA    . ASP A 1 261 ? 137.751 155.458 129.013 1.00 12.42  ? 261 ASP A CA    1 
ATOM   930  C C     . ASP A 1 261 ? 139.132 155.085 128.494 1.00 13.61  ? 261 ASP A C     1 
ATOM   931  O O     . ASP A 1 261 ? 140.053 154.913 129.300 1.00 18.56  ? 261 ASP A O     1 
ATOM   932  C CB    . ASP A 1 261 ? 137.264 154.385 129.994 1.00 15.72  ? 261 ASP A CB    1 
ATOM   933  N N     . THR A 1 262 ? 139.305 154.952 127.182 1.00 14.43  ? 262 THR A N     1 
ATOM   934  C CA    . THR A 1 262 ? 140.603 154.578 126.636 1.00 10.55  ? 262 THR A CA    1 
ATOM   935  C C     . THR A 1 262 ? 141.586 155.734 126.773 1.00 7.98   ? 262 THR A C     1 
ATOM   936  O O     . THR A 1 262 ? 141.277 156.874 126.414 1.00 11.85  ? 262 THR A O     1 
ATOM   937  C CB    . THR A 1 262 ? 140.467 154.170 125.170 1.00 5.16   ? 262 THR A CB    1 
ATOM   938  O OG1   . THR A 1 262 ? 139.474 153.146 125.049 1.00 15.09  ? 262 THR A OG1   1 
ATOM   939  C CG2   . THR A 1 262 ? 141.789 153.642 124.643 1.00 2.60   ? 262 THR A CG2   1 
ATOM   940  N N     . SER A 1 263 ? 142.772 155.437 127.297 1.00 8.79   ? 263 SER A N     1 
ATOM   941  C CA    . SER A 1 263 ? 143.799 156.451 127.465 1.00 6.65   ? 263 SER A CA    1 
ATOM   942  C C     . SER A 1 263 ? 144.479 156.756 126.134 1.00 2.58   ? 263 SER A C     1 
ATOM   943  O O     . SER A 1 263 ? 144.526 155.926 125.220 1.00 9.27   ? 263 SER A O     1 
ATOM   944  C CB    . SER A 1 263 ? 144.836 156.005 128.494 1.00 7.56   ? 263 SER A CB    1 
ATOM   945  N N     . ILE A 1 264 ? 145.011 157.971 126.036 1.00 0.00   ? 264 ILE A N     1 
ATOM   946  C CA    . ILE A 1 264 ? 145.655 158.464 124.826 1.00 2.38   ? 264 ILE A CA    1 
ATOM   947  C C     . ILE A 1 264 ? 147.067 158.912 125.171 1.00 0.00   ? 264 ILE A C     1 
ATOM   948  O O     . ILE A 1 264 ? 147.264 159.719 126.085 1.00 11.70  ? 264 ILE A O     1 
ATOM   949  C CB    . ILE A 1 264 ? 144.860 159.618 124.189 1.00 5.09   ? 264 ILE A CB    1 
ATOM   950  C CG1   . ILE A 1 264 ? 143.409 159.200 123.952 1.00 3.88   ? 264 ILE A CG1   1 
ATOM   951  C CG2   . ILE A 1 264 ? 145.511 160.058 122.887 1.00 2.40   ? 264 ILE A CG2   1 
ATOM   952  C CD1   . ILE A 1 264 ? 142.556 160.287 123.353 1.00 9.45   ? 264 ILE A CD1   1 
ATOM   953  N N     . ILE A 1 265 ? 148.041 158.385 124.440 1.00 0.00   ? 265 ILE A N     1 
ATOM   954  C CA    . ILE A 1 265 ? 149.426 158.828 124.509 1.00 0.00   ? 265 ILE A CA    1 
ATOM   955  C C     . ILE A 1 265 ? 149.638 159.800 123.357 1.00 2.27   ? 265 ILE A C     1 
ATOM   956  O O     . ILE A 1 265 ? 149.644 159.401 122.188 1.00 7.12   ? 265 ILE A O     1 
ATOM   957  C CB    . ILE A 1 265 ? 150.403 157.648 124.432 1.00 4.09   ? 265 ILE A CB    1 
ATOM   958  C CG1   . ILE A 1 265 ? 150.159 156.675 125.586 1.00 2.92   ? 265 ILE A CG1   1 
ATOM   959  C CG2   . ILE A 1 265 ? 151.841 158.144 124.441 1.00 7.46   ? 265 ILE A CG2   1 
ATOM   960  C CD1   . ILE A 1 265 ? 150.592 155.258 125.285 1.00 4.70   ? 265 ILE A CD1   1 
ATOM   961  N N     . LEU A 1 266 ? 149.802 161.079 123.679 1.00 1.42   ? 266 LEU A N     1 
ATOM   962  C CA    . LEU A 1 266 ? 149.954 162.121 122.670 1.00 0.00   ? 266 LEU A CA    1 
ATOM   963  C C     . LEU A 1 266 ? 151.439 162.334 122.404 1.00 5.25   ? 266 LEU A C     1 
ATOM   964  O O     . LEU A 1 266 ? 152.175 162.797 123.281 1.00 7.30   ? 266 LEU A O     1 
ATOM   965  C CB    . LEU A 1 266 ? 149.282 163.413 123.124 1.00 3.73   ? 266 LEU A CB    1 
ATOM   966  C CG    . LEU A 1 266 ? 149.387 164.602 122.168 1.00 7.15   ? 266 LEU A CG    1 
ATOM   967  C CD1   . LEU A 1 266 ? 148.570 164.352 120.911 1.00 8.30   ? 266 LEU A CD1   1 
ATOM   968  C CD2   . LEU A 1 266 ? 148.941 165.881 122.855 1.00 11.25  ? 266 LEU A CD2   1 
ATOM   969  N N     . PHE A 1 267 ? 151.878 161.996 121.196 1.00 12.19  ? 267 PHE A N     1 
ATOM   970  C CA    . PHE A 1 267 ? 153.261 162.185 120.778 1.00 10.44  ? 267 PHE A CA    1 
ATOM   971  C C     . PHE A 1 267 ? 153.336 163.438 119.915 1.00 14.26  ? 267 PHE A C     1 
ATOM   972  O O     . PHE A 1 267 ? 152.895 163.433 118.761 1.00 21.17  ? 267 PHE A O     1 
ATOM   973  C CB    . PHE A 1 267 ? 153.774 160.964 120.021 1.00 13.50  ? 267 PHE A CB    1 
ATOM   974  C CG    . PHE A 1 267 ? 154.380 159.916 120.905 1.00 16.47  ? 267 PHE A CG    1 
ATOM   975  C CD1   . PHE A 1 267 ? 155.417 160.233 121.765 1.00 17.55  ? 267 PHE A CD1   1 
ATOM   976  C CD2   . PHE A 1 267 ? 153.915 158.615 120.878 1.00 17.94  ? 267 PHE A CD2   1 
ATOM   977  C CE1   . PHE A 1 267 ? 155.977 159.271 122.580 1.00 17.56  ? 267 PHE A CE1   1 
ATOM   978  C CE2   . PHE A 1 267 ? 154.470 157.649 121.691 1.00 19.49  ? 267 PHE A CE2   1 
ATOM   979  C CZ    . PHE A 1 267 ? 155.503 157.978 122.543 1.00 16.68  ? 267 PHE A CZ    1 
ATOM   980  N N     . LEU A 1 268 ? 153.896 164.508 120.476 1.00 11.47  ? 268 LEU A N     1 
ATOM   981  C CA    . LEU A 1 268 ? 154.101 165.755 119.744 1.00 16.12  ? 268 LEU A CA    1 
ATOM   982  C C     . LEU A 1 268 ? 155.461 165.664 119.064 1.00 19.39  ? 268 LEU A C     1 
ATOM   983  O O     . LEU A 1 268 ? 156.493 166.031 119.627 1.00 22.38  ? 268 LEU A O     1 
ATOM   984  C CB    . LEU A 1 268 ? 153.997 166.953 120.678 1.00 17.48  ? 268 LEU A CB    1 
ATOM   985  C CG    . LEU A 1 268 ? 152.617 167.150 121.310 1.00 13.00  ? 268 LEU A CG    1 
ATOM   986  C CD1   . LEU A 1 268 ? 152.633 168.287 122.315 1.00 18.91  ? 268 LEU A CD1   1 
ATOM   987  C CD2   . LEU A 1 268 ? 151.566 167.393 120.240 1.00 16.94  ? 268 LEU A CD2   1 
ATOM   988  N N     . ASN A 1 269 ? 155.453 165.164 117.833 1.00 18.70  ? 269 ASN A N     1 
ATOM   989  C CA    . ASN A 1 269 ? 156.675 164.873 117.103 1.00 20.11  ? 269 ASN A CA    1 
ATOM   990  C C     . ASN A 1 269 ? 157.221 166.129 116.429 1.00 28.39  ? 269 ASN A C     1 
ATOM   991  O O     . ASN A 1 269 ? 156.602 167.196 116.435 1.00 27.03  ? 269 ASN A O     1 
ATOM   992  C CB    . ASN A 1 269 ? 156.425 163.781 116.064 1.00 21.84  ? 269 ASN A CB    1 
ATOM   993  C CG    . ASN A 1 269 ? 156.067 162.451 116.693 1.00 26.76  ? 269 ASN A CG    1 
ATOM   994  O OD1   . ASN A 1 269 ? 156.639 162.058 117.710 1.00 31.24  ? 269 ASN A OD1   1 
ATOM   995  N ND2   . ASN A 1 269 ? 155.113 161.749 116.091 1.00 24.12  ? 269 ASN A ND2   1 
ATOM   996  N N     . LYS A 1 270 ? 158.410 165.980 115.840 1.00 32.43  ? 270 LYS A N     1 
ATOM   997  C CA    . LYS A 1 270 ? 159.075 167.050 115.093 1.00 31.68  ? 270 LYS A CA    1 
ATOM   998  C C     . LYS A 1 270 ? 159.279 168.294 115.954 1.00 30.61  ? 270 LYS A C     1 
ATOM   999  O O     . LYS A 1 270 ? 159.091 169.424 115.499 1.00 31.06  ? 270 LYS A O     1 
ATOM   1000 C CB    . LYS A 1 270 ? 158.304 167.392 113.816 1.00 30.15  ? 270 LYS A CB    1 
ATOM   1001 C CG    . LYS A 1 270 ? 158.038 166.196 112.918 1.00 28.68  ? 270 LYS A CG    1 
ATOM   1002 C CD    . LYS A 1 270 ? 157.556 166.631 111.545 1.00 31.29  ? 270 LYS A CD    1 
ATOM   1003 C CE    . LYS A 1 270 ? 157.319 165.434 110.640 1.00 33.21  ? 270 LYS A CE    1 
ATOM   1004 N NZ    . LYS A 1 270 ? 156.996 165.849 109.248 1.00 32.98  ? 270 LYS A NZ    1 
ATOM   1005 N N     . LYS A 1 271 ? 159.666 168.086 117.215 1.00 29.03  ? 271 LYS A N     1 
ATOM   1006 C CA    . LYS A 1 271 ? 159.946 169.220 118.088 1.00 30.85  ? 271 LYS A CA    1 
ATOM   1007 C C     . LYS A 1 271 ? 161.237 169.927 117.693 1.00 34.87  ? 271 LYS A C     1 
ATOM   1008 O O     . LYS A 1 271 ? 161.371 171.137 117.911 1.00 35.56  ? 271 LYS A O     1 
ATOM   1009 C CB    . LYS A 1 271 ? 159.998 168.762 119.548 1.00 32.31  ? 271 LYS A CB    1 
ATOM   1010 C CG    . LYS A 1 271 ? 161.322 168.153 119.985 1.00 32.22  ? 271 LYS A CG    1 
ATOM   1011 C CD    . LYS A 1 271 ? 161.219 167.560 121.381 1.00 33.99  ? 271 LYS A CD    1 
ATOM   1012 C CE    . LYS A 1 271 ? 162.588 167.409 122.022 1.00 34.62  ? 271 LYS A CE    1 
ATOM   1013 N NZ    . LYS A 1 271 ? 163.372 166.301 121.412 1.00 34.37  ? 271 LYS A NZ    1 
ATOM   1014 N N     . ASP A 1 272 ? 162.190 169.197 117.105 1.00 33.79  ? 272 ASP A N     1 
ATOM   1015 C CA    . ASP A 1 272 ? 163.428 169.824 116.652 1.00 31.70  ? 272 ASP A CA    1 
ATOM   1016 C C     . ASP A 1 272 ? 163.161 170.824 115.534 1.00 33.94  ? 272 ASP A C     1 
ATOM   1017 O O     . ASP A 1 272 ? 163.721 171.926 115.529 1.00 33.28  ? 272 ASP A O     1 
ATOM   1018 C CB    . ASP A 1 272 ? 164.420 168.756 116.193 1.00 29.06  ? 272 ASP A CB    1 
ATOM   1019 N N     . LEU A 1 273 ? 162.307 170.457 114.575 1.00 33.60  ? 273 LEU A N     1 
ATOM   1020 C CA    . LEU A 1 273 ? 161.935 171.396 113.523 1.00 33.21  ? 273 LEU A CA    1 
ATOM   1021 C C     . LEU A 1 273 ? 161.010 172.484 114.050 1.00 34.87  ? 273 LEU A C     1 
ATOM   1022 O O     . LEU A 1 273 ? 161.039 173.616 113.553 1.00 36.37  ? 273 LEU A O     1 
ATOM   1023 C CB    . LEU A 1 273 ? 161.274 170.653 112.362 1.00 29.27  ? 273 LEU A CB    1 
ATOM   1024 N N     . PHE A 1 274 ? 160.186 172.162 115.049 1.00 34.59  ? 274 PHE A N     1 
ATOM   1025 C CA    . PHE A 1 274 ? 159.305 173.164 115.639 1.00 33.65  ? 274 PHE A CA    1 
ATOM   1026 C C     . PHE A 1 274 ? 160.102 174.254 116.343 1.00 34.16  ? 274 PHE A C     1 
ATOM   1027 O O     . PHE A 1 274 ? 159.711 175.427 116.323 1.00 34.77  ? 274 PHE A O     1 
ATOM   1028 C CB    . PHE A 1 274 ? 158.331 172.499 116.610 1.00 33.17  ? 274 PHE A CB    1 
ATOM   1029 C CG    . PHE A 1 274 ? 157.413 173.463 117.302 1.00 32.90  ? 274 PHE A CG    1 
ATOM   1030 C CD1   . PHE A 1 274 ? 156.420 174.121 116.597 1.00 33.64  ? 274 PHE A CD1   1 
ATOM   1031 C CD2   . PHE A 1 274 ? 157.543 173.712 118.658 1.00 34.77  ? 274 PHE A CD2   1 
ATOM   1032 C CE1   . PHE A 1 274 ? 155.574 175.008 117.231 1.00 34.69  ? 274 PHE A CE1   1 
ATOM   1033 C CE2   . PHE A 1 274 ? 156.700 174.599 119.297 1.00 34.37  ? 274 PHE A CE2   1 
ATOM   1034 C CZ    . PHE A 1 274 ? 155.714 175.248 118.582 1.00 34.76  ? 274 PHE A CZ    1 
ATOM   1035 N N     . GLU A 1 275 ? 161.218 173.885 116.978 1.00 34.75  ? 275 GLU A N     1 
ATOM   1036 C CA    . GLU A 1 275 ? 162.061 174.883 117.629 1.00 37.73  ? 275 GLU A CA    1 
ATOM   1037 C C     . GLU A 1 275 ? 162.627 175.870 116.616 1.00 37.77  ? 275 GLU A C     1 
ATOM   1038 O O     . GLU A 1 275 ? 162.691 177.076 116.882 1.00 35.98  ? 275 GLU A O     1 
ATOM   1039 C CB    . GLU A 1 275 ? 163.189 174.196 118.399 1.00 33.55  ? 275 GLU A CB    1 
ATOM   1040 N N     . GLU A 1 276 ? 163.050 175.377 115.450 1.00 35.96  ? 276 GLU A N     1 
ATOM   1041 C CA    . GLU A 1 276 ? 163.560 176.268 114.414 1.00 35.60  ? 276 GLU A CA    1 
ATOM   1042 C C     . GLU A 1 276 ? 162.444 177.107 113.804 1.00 36.20  ? 276 GLU A C     1 
ATOM   1043 O O     . GLU A 1 276 ? 162.643 178.290 113.503 1.00 35.55  ? 276 GLU A O     1 
ATOM   1044 C CB    . GLU A 1 276 ? 164.276 175.459 113.333 1.00 32.80  ? 276 GLU A CB    1 
ATOM   1045 N N     . LYS A 1 277 ? 161.264 176.513 113.610 1.00 37.65  ? 277 LYS A N     1 
ATOM   1046 C CA    . LYS A 1 277 ? 160.161 177.241 112.990 1.00 37.42  ? 277 LYS A CA    1 
ATOM   1047 C C     . LYS A 1 277 ? 159.637 178.346 113.900 1.00 38.83  ? 277 LYS A C     1 
ATOM   1048 O O     . LYS A 1 277 ? 159.269 179.426 113.423 1.00 39.50  ? 277 LYS A O     1 
ATOM   1049 C CB    . LYS A 1 277 ? 159.037 176.275 112.618 1.00 36.18  ? 277 LYS A CB    1 
ATOM   1050 C CG    . LYS A 1 277 ? 159.247 175.561 111.294 1.00 37.19  ? 277 LYS A CG    1 
ATOM   1051 C CD    . LYS A 1 277 ? 157.987 174.834 110.854 1.00 38.03  ? 277 LYS A CD    1 
ATOM   1052 C CE    . LYS A 1 277 ? 158.127 174.293 109.441 1.00 37.91  ? 277 LYS A CE    1 
ATOM   1053 N NZ    . LYS A 1 277 ? 158.156 175.385 108.430 1.00 37.96  ? 277 LYS A NZ    1 
ATOM   1054 N N     . ILE A 1 278 ? 159.592 178.097 115.211 1.00 39.29  ? 278 ILE A N     1 
ATOM   1055 C CA    . ILE A 1 278 ? 159.047 179.083 116.137 1.00 41.74  ? 278 ILE A CA    1 
ATOM   1056 C C     . ILE A 1 278 ? 159.946 180.307 116.257 1.00 42.90  ? 278 ILE A C     1 
ATOM   1057 O O     . ILE A 1 278 ? 159.499 181.354 116.740 1.00 45.05  ? 278 ILE A O     1 
ATOM   1058 C CB    . ILE A 1 278 ? 158.806 178.443 117.518 1.00 40.86  ? 278 ILE A CB    1 
ATOM   1059 C CG1   . ILE A 1 278 ? 157.706 179.193 118.272 1.00 41.84  ? 278 ILE A CG1   1 
ATOM   1060 C CG2   . ILE A 1 278 ? 160.089 178.418 118.334 1.00 38.22  ? 278 ILE A CG2   1 
ATOM   1061 C CD1   . ILE A 1 278 ? 156.363 179.164 117.578 1.00 41.56  ? 278 ILE A CD1   1 
ATOM   1062 N N     . LYS A 1 279 ? 161.206 180.208 115.826 1.00 40.72  ? 279 LYS A N     1 
ATOM   1063 C CA    . LYS A 1 279 ? 162.108 181.351 115.894 1.00 41.01  ? 279 LYS A CA    1 
ATOM   1064 C C     . LYS A 1 279 ? 161.757 182.432 114.880 1.00 40.40  ? 279 LYS A C     1 
ATOM   1065 O O     . LYS A 1 279 ? 162.123 183.594 115.082 1.00 39.67  ? 279 LYS A O     1 
ATOM   1066 C CB    . LYS A 1 279 ? 163.553 180.894 115.687 1.00 38.43  ? 279 LYS A CB    1 
ATOM   1067 N N     . LYS A 1 280 ? 161.060 182.080 113.800 1.00 38.95  ? 280 LYS A N     1 
ATOM   1068 C CA    . LYS A 1 280 ? 160.719 183.051 112.767 1.00 39.87  ? 280 LYS A CA    1 
ATOM   1069 C C     . LYS A 1 280 ? 159.217 183.084 112.515 1.00 41.01  ? 280 LYS A C     1 
ATOM   1070 O O     . LYS A 1 280 ? 158.657 184.140 112.206 1.00 39.24  ? 280 LYS A O     1 
ATOM   1071 C CB    . LYS A 1 280 ? 161.466 182.735 111.470 1.00 37.36  ? 280 LYS A CB    1 
ATOM   1072 N N     . SER A 1 281 ? 158.555 181.933 112.644 1.00 41.05  ? 281 SER A N     1 
ATOM   1073 C CA    . SER A 1 281 ? 157.122 181.850 112.413 1.00 40.54  ? 281 SER A CA    1 
ATOM   1074 C C     . SER A 1 281 ? 156.394 181.892 113.747 1.00 41.02  ? 281 SER A C     1 
ATOM   1075 O O     . SER A 1 281 ? 156.533 180.953 114.545 1.00 39.83  ? 281 SER A O     1 
ATOM   1076 C CB    . SER A 1 281 ? 156.771 180.572 111.654 1.00 37.77  ? 281 SER A CB    1 
ATOM   1077 N N     . PRO A 1 282 ? 155.627 182.940 114.038 1.00 41.56  ? 282 PRO A N     1 
ATOM   1078 C CA    . PRO A 1 282 ? 154.915 182.997 115.318 1.00 40.38  ? 282 PRO A CA    1 
ATOM   1079 C C     . PRO A 1 282 ? 153.794 181.972 115.387 1.00 38.97  ? 282 PRO A C     1 
ATOM   1080 O O     . PRO A 1 282 ? 153.232 181.556 114.371 1.00 36.96  ? 282 PRO A O     1 
ATOM   1081 C CB    . PRO A 1 282 ? 154.363 184.426 115.352 1.00 39.58  ? 282 PRO A CB    1 
ATOM   1082 C CG    . PRO A 1 282 ? 154.224 184.800 113.915 1.00 40.50  ? 282 PRO A CG    1 
ATOM   1083 C CD    . PRO A 1 282 ? 155.361 184.122 113.201 1.00 38.61  ? 282 PRO A CD    1 
ATOM   1084 N N     . LEU A 1 283 ? 153.472 181.565 116.617 1.00 38.16  ? 283 LEU A N     1 
ATOM   1085 C CA    . LEU A 1 283 ? 152.377 180.631 116.848 1.00 37.64  ? 283 LEU A CA    1 
ATOM   1086 C C     . LEU A 1 283 ? 151.012 181.251 116.575 1.00 39.87  ? 283 LEU A C     1 
ATOM   1087 O O     . LEU A 1 283 ? 150.021 180.517 116.495 1.00 41.24  ? 283 LEU A O     1 
ATOM   1088 C CB    . LEU A 1 283 ? 152.442 180.105 118.286 1.00 35.18  ? 283 LEU A CB    1 
ATOM   1089 C CG    . LEU A 1 283 ? 151.553 178.920 118.672 1.00 37.90  ? 283 LEU A CG    1 
ATOM   1090 C CD1   . LEU A 1 283 ? 151.848 177.716 117.793 1.00 35.32  ? 283 LEU A CD1   1 
ATOM   1091 C CD2   . LEU A 1 283 ? 151.728 178.571 120.141 1.00 39.07  ? 283 LEU A CD2   1 
ATOM   1092 N N     . THR A 1 284 ? 150.938 182.575 116.414 1.00 38.79  ? 284 THR A N     1 
ATOM   1093 C CA    . THR A 1 284 ? 149.661 183.231 116.159 1.00 38.44  ? 284 THR A CA    1 
ATOM   1094 C C     . THR A 1 284 ? 149.058 182.829 114.819 1.00 37.37  ? 284 THR A C     1 
ATOM   1095 O O     . THR A 1 284 ? 147.872 183.090 114.585 1.00 36.87  ? 284 THR A O     1 
ATOM   1096 C CB    . THR A 1 284 ? 149.828 184.751 116.214 1.00 37.40  ? 284 THR A CB    1 
ATOM   1097 N N     . ILE A 1 285 ? 149.845 182.213 113.934 1.00 35.61  ? 285 ILE A N     1 
ATOM   1098 C CA    . ILE A 1 285 ? 149.305 181.734 112.665 1.00 37.56  ? 285 ILE A CA    1 
ATOM   1099 C C     . ILE A 1 285 ? 148.247 180.665 112.908 1.00 37.62  ? 285 ILE A C     1 
ATOM   1100 O O     . ILE A 1 285 ? 147.182 180.668 112.279 1.00 37.05  ? 285 ILE A O     1 
ATOM   1101 C CB    . ILE A 1 285 ? 150.440 181.215 111.763 1.00 38.97  ? 285 ILE A CB    1 
ATOM   1102 C CG1   . ILE A 1 285 ? 151.388 182.356 111.388 1.00 38.68  ? 285 ILE A CG1   1 
ATOM   1103 C CG2   . ILE A 1 285 ? 149.875 180.558 110.513 1.00 36.62  ? 285 ILE A CG2   1 
ATOM   1104 C CD1   . ILE A 1 285 ? 152.681 181.891 110.754 1.00 38.37  ? 285 ILE A CD1   1 
ATOM   1105 N N     . CYS A 1 286 ? 148.520 179.738 113.826 1.00 39.85  ? 286 CYS A N     1 
ATOM   1106 C CA    . CYS A 1 286 ? 147.566 178.690 114.164 1.00 40.35  ? 286 CYS A CA    1 
ATOM   1107 C C     . CYS A 1 286 ? 146.580 179.143 115.237 1.00 37.97  ? 286 CYS A C     1 
ATOM   1108 O O     . CYS A 1 286 ? 145.366 178.996 115.069 1.00 37.68  ? 286 CYS A O     1 
ATOM   1109 C CB    . CYS A 1 286 ? 148.309 177.432 114.624 1.00 37.22  ? 286 CYS A CB    1 
ATOM   1110 N N     . TYR A 1 287 ? 147.084 179.693 116.338 1.00 37.20  ? 287 TYR A N     1 
ATOM   1111 C CA    . TYR A 1 287 ? 146.245 180.155 117.444 1.00 40.44  ? 287 TYR A CA    1 
ATOM   1112 C C     . TYR A 1 287 ? 146.416 181.655 117.629 1.00 39.61  ? 287 TYR A C     1 
ATOM   1113 O O     . TYR A 1 287 ? 147.392 182.099 118.260 1.00 38.46  ? 287 TYR A O     1 
ATOM   1114 C CB    . TYR A 1 287 ? 146.594 179.414 118.734 1.00 38.74  ? 287 TYR A CB    1 
ATOM   1115 C CG    . TYR A 1 287 ? 146.574 177.909 118.601 1.00 38.29  ? 287 TYR A CG    1 
ATOM   1116 C CD1   . TYR A 1 287 ? 145.522 177.264 117.966 1.00 36.50  ? 287 TYR A CD1   1 
ATOM   1117 C CD2   . TYR A 1 287 ? 147.607 177.134 119.109 1.00 34.57  ? 287 TYR A CD2   1 
ATOM   1118 C CE1   . TYR A 1 287 ? 145.499 175.889 117.841 1.00 36.72  ? 287 TYR A CE1   1 
ATOM   1119 C CE2   . TYR A 1 287 ? 147.593 175.758 118.990 1.00 34.00  ? 287 TYR A CE2   1 
ATOM   1120 C CZ    . TYR A 1 287 ? 146.536 175.141 118.355 1.00 37.80  ? 287 TYR A CZ    1 
ATOM   1121 O OH    . TYR A 1 287 ? 146.517 173.771 118.234 1.00 37.42  ? 287 TYR A OH    1 
ATOM   1122 N N     . PRO A 1 288 ? 145.507 182.476 117.097 1.00 38.58  ? 288 PRO A N     1 
ATOM   1123 C CA    . PRO A 1 288 ? 145.615 183.928 117.318 1.00 37.67  ? 288 PRO A CA    1 
ATOM   1124 C C     . PRO A 1 288 ? 145.529 184.324 118.781 1.00 39.08  ? 288 PRO A C     1 
ATOM   1125 O O     . PRO A 1 288 ? 146.114 185.341 119.174 1.00 41.25  ? 288 PRO A O     1 
ATOM   1126 C CB    . PRO A 1 288 ? 144.438 184.494 116.510 1.00 38.11  ? 288 PRO A CB    1 
ATOM   1127 C CG    . PRO A 1 288 ? 144.095 183.423 115.521 1.00 38.18  ? 288 PRO A CG    1 
ATOM   1128 C CD    . PRO A 1 288 ? 144.378 182.130 116.218 1.00 37.73  ? 288 PRO A CD    1 
ATOM   1129 N N     . GLU A 1 289 ? 144.816 183.550 119.601 1.00 40.31  ? 289 GLU A N     1 
ATOM   1130 C CA    . GLU A 1 289 ? 144.643 183.883 121.010 1.00 42.02  ? 289 GLU A CA    1 
ATOM   1131 C C     . GLU A 1 289 ? 145.913 183.695 121.829 1.00 40.90  ? 289 GLU A C     1 
ATOM   1132 O O     . GLU A 1 289 ? 145.941 184.107 122.994 1.00 39.90  ? 289 GLU A O     1 
ATOM   1133 C CB    . GLU A 1 289 ? 143.515 183.042 121.611 1.00 39.09  ? 289 GLU A CB    1 
ATOM   1134 N N     . TYR A 1 290 ? 146.953 183.086 121.260 1.00 38.53  ? 290 TYR A N     1 
ATOM   1135 C CA    . TYR A 1 290 ? 148.197 182.858 121.986 1.00 39.12  ? 290 TYR A CA    1 
ATOM   1136 C C     . TYR A 1 290 ? 148.884 184.176 122.319 1.00 39.44  ? 290 TYR A C     1 
ATOM   1137 O O     . TYR A 1 290 ? 149.451 184.829 121.438 1.00 38.99  ? 290 TYR A O     1 
ATOM   1138 C CB    . TYR A 1 290 ? 149.132 181.963 121.170 1.00 39.77  ? 290 TYR A CB    1 
ATOM   1139 C CG    . TYR A 1 290 ? 150.484 181.746 121.809 1.00 38.80  ? 290 TYR A CG    1 
ATOM   1140 C CD1   . TYR A 1 290 ? 150.593 181.206 123.084 1.00 38.74  ? 290 TYR A CD1   1 
ATOM   1141 C CD2   . TYR A 1 290 ? 151.652 182.084 121.139 1.00 37.84  ? 290 TYR A CD2   1 
ATOM   1142 C CE1   . TYR A 1 290 ? 151.828 181.007 123.671 1.00 39.33  ? 290 TYR A CE1   1 
ATOM   1143 C CE2   . TYR A 1 290 ? 152.890 181.888 121.718 1.00 40.47  ? 290 TYR A CE2   1 
ATOM   1144 C CZ    . TYR A 1 290 ? 152.972 181.350 122.984 1.00 40.15  ? 290 TYR A CZ    1 
ATOM   1145 O OH    . TYR A 1 290 ? 154.204 181.154 123.564 1.00 37.19  ? 290 TYR A OH    1 
ATOM   1146 N N     . ALA A 1 291 ? 148.839 184.572 123.591 1.00 40.22  ? 291 ALA A N     1 
ATOM   1147 C CA    . ALA A 1 291 ? 149.448 185.815 124.041 1.00 40.65  ? 291 ALA A CA    1 
ATOM   1148 C C     . ALA A 1 291 ? 150.858 185.632 124.586 1.00 41.39  ? 291 ALA A C     1 
ATOM   1149 O O     . ALA A 1 291 ? 151.492 186.625 124.961 1.00 40.13  ? 291 ALA A O     1 
ATOM   1150 C CB    . ALA A 1 291 ? 148.573 186.476 125.113 1.00 37.63  ? 291 ALA A CB    1 
ATOM   1151 N N     . GLY A 1 292 ? 151.363 184.400 124.640 1.00 42.27  ? 292 GLY A N     1 
ATOM   1152 C CA    . GLY A 1 292 ? 152.691 184.162 125.162 1.00 41.35  ? 292 GLY A CA    1 
ATOM   1153 C C     . GLY A 1 292 ? 153.786 184.524 124.176 1.00 40.75  ? 292 GLY A C     1 
ATOM   1154 O O     . GLY A 1 292 ? 153.550 184.777 122.995 1.00 37.74  ? 292 GLY A O     1 
ATOM   1155 N N     . SER A 1 293 ? 155.013 184.550 124.690 1.00 43.14  ? 293 SER A N     1 
ATOM   1156 C CA    . SER A 1 293 ? 156.168 184.854 123.860 1.00 43.85  ? 293 SER A CA    1 
ATOM   1157 C C     . SER A 1 293 ? 156.434 183.723 122.873 1.00 44.63  ? 293 SER A C     1 
ATOM   1158 O O     . SER A 1 293 ? 156.198 182.547 123.160 1.00 44.08  ? 293 SER A O     1 
ATOM   1159 C CB    . SER A 1 293 ? 157.403 185.092 124.728 1.00 41.98  ? 293 SER A CB    1 
ATOM   1160 N N     . ASN A 1 294 ? 156.934 184.093 121.693 1.00 43.96  ? 294 ASN A N     1 
ATOM   1161 C CA    . ASN A 1 294 ? 157.228 183.127 120.635 1.00 44.49  ? 294 ASN A CA    1 
ATOM   1162 C C     . ASN A 1 294 ? 158.525 182.401 120.983 1.00 48.11  ? 294 ASN A C     1 
ATOM   1163 O O     . ASN A 1 294 ? 159.598 182.661 120.432 1.00 47.78  ? 294 ASN A O     1 
ATOM   1164 C CB    . ASN A 1 294 ? 157.312 183.819 119.281 1.00 44.19  ? 294 ASN A CB    1 
ATOM   1165 C CG    . ASN A 1 294 ? 155.972 184.357 118.819 1.00 46.05  ? 294 ASN A CG    1 
ATOM   1166 O OD1   . ASN A 1 294 ? 155.026 183.599 118.607 1.00 46.00  ? 294 ASN A OD1   1 
ATOM   1167 N ND2   . ASN A 1 294 ? 155.886 185.673 118.660 1.00 45.96  ? 294 ASN A ND2   1 
ATOM   1168 N N     . THR A 1 295 ? 158.413 181.466 121.922 1.00 45.02  ? 295 THR A N     1 
ATOM   1169 C CA    . THR A 1 295 ? 159.528 180.635 122.348 1.00 42.89  ? 295 THR A CA    1 
ATOM   1170 C C     . THR A 1 295 ? 159.119 179.173 122.248 1.00 42.39  ? 295 THR A C     1 
ATOM   1171 O O     . THR A 1 295 ? 157.936 178.834 122.312 1.00 42.04  ? 295 THR A O     1 
ATOM   1172 C CB    . THR A 1 295 ? 159.970 180.962 123.781 1.00 40.57  ? 295 THR A CB    1 
ATOM   1173 N N     . TYR A 1 296 ? 160.120 178.305 122.085 1.00 39.46  ? 296 TYR A N     1 
ATOM   1174 C CA    . TYR A 1 296 ? 159.845 176.885 121.885 1.00 38.57  ? 296 TYR A CA    1 
ATOM   1175 C C     . TYR A 1 296 ? 159.112 176.287 123.080 1.00 39.26  ? 296 TYR A C     1 
ATOM   1176 O O     . TYR A 1 296 ? 158.112 175.579 122.917 1.00 40.38  ? 296 TYR A O     1 
ATOM   1177 C CB    . TYR A 1 296 ? 161.148 176.130 121.622 1.00 37.77  ? 296 TYR A CB    1 
ATOM   1178 C CG    . TYR A 1 296 ? 161.049 174.643 121.876 1.00 40.38  ? 296 TYR A CG    1 
ATOM   1179 C CD1   . TYR A 1 296 ? 160.286 173.828 121.051 1.00 37.91  ? 296 TYR A CD1   1 
ATOM   1180 C CD2   . TYR A 1 296 ? 161.714 174.056 122.944 1.00 39.77  ? 296 TYR A CD2   1 
ATOM   1181 C CE1   . TYR A 1 296 ? 160.190 172.469 121.281 1.00 38.04  ? 296 TYR A CE1   1 
ATOM   1182 C CE2   . TYR A 1 296 ? 161.624 172.698 123.182 1.00 41.54  ? 296 TYR A CE2   1 
ATOM   1183 C CZ    . TYR A 1 296 ? 160.861 171.909 122.348 1.00 40.19  ? 296 TYR A CZ    1 
ATOM   1184 O OH    . TYR A 1 296 ? 160.769 170.557 122.581 1.00 37.72  ? 296 TYR A OH    1 
ATOM   1185 N N     . GLU A 1 297 ? 159.590 176.571 124.293 1.00 35.59  ? 297 GLU A N     1 
ATOM   1186 C CA    . GLU A 1 297 ? 158.984 175.984 125.484 1.00 36.93  ? 297 GLU A CA    1 
ATOM   1187 C C     . GLU A 1 297 ? 157.558 176.482 125.684 1.00 36.12  ? 297 GLU A C     1 
ATOM   1188 O O     . GLU A 1 297 ? 156.637 175.687 125.910 1.00 35.43  ? 297 GLU A O     1 
ATOM   1189 C CB    . GLU A 1 297 ? 159.841 176.292 126.713 1.00 34.50  ? 297 GLU A CB    1 
ATOM   1190 N N     . GLU A 1 298 ? 157.356 177.800 125.602 1.00 36.33  ? 298 GLU A N     1 
ATOM   1191 C CA    . GLU A 1 298 ? 156.026 178.360 125.821 1.00 36.85  ? 298 GLU A CA    1 
ATOM   1192 C C     . GLU A 1 298 ? 155.047 177.906 124.745 1.00 35.66  ? 298 GLU A C     1 
ATOM   1193 O O     . GLU A 1 298 ? 153.901 177.552 125.049 1.00 34.35  ? 298 GLU A O     1 
ATOM   1194 C CB    . GLU A 1 298 ? 156.103 179.886 125.869 1.00 35.99  ? 298 GLU A CB    1 
ATOM   1195 N N     . ALA A 1 299 ? 155.477 177.910 123.481 1.00 33.41  ? 299 ALA A N     1 
ATOM   1196 C CA    . ALA A 1 299 ? 154.598 177.473 122.402 1.00 34.57  ? 299 ALA A CA    1 
ATOM   1197 C C     . ALA A 1 299 ? 154.256 175.994 122.529 1.00 33.18  ? 299 ALA A C     1 
ATOM   1198 O O     . ALA A 1 299 ? 153.107 175.595 122.303 1.00 33.19  ? 299 ALA A O     1 
ATOM   1199 C CB    . ALA A 1 299 ? 155.241 177.761 121.046 1.00 35.06  ? 299 ALA A CB    1 
ATOM   1200 N N     . ALA A 1 300 ? 155.241 175.164 122.883 1.00 29.27  ? 300 ALA A N     1 
ATOM   1201 C CA    . ALA A 1 300 ? 154.976 173.742 123.072 1.00 29.88  ? 300 ALA A CA    1 
ATOM   1202 C C     . ALA A 1 300 ? 154.001 173.513 124.219 1.00 31.72  ? 300 ALA A C     1 
ATOM   1203 O O     . ALA A 1 300 ? 153.088 172.685 124.113 1.00 30.82  ? 300 ALA A O     1 
ATOM   1204 C CB    . ALA A 1 300 ? 156.285 172.994 123.319 1.00 30.05  ? 300 ALA A CB    1 
ATOM   1205 N N     . ALA A 1 301 ? 154.178 174.241 125.326 1.00 33.64  ? 301 ALA A N     1 
ATOM   1206 C CA    . ALA A 1 301 ? 153.255 174.114 126.449 1.00 31.35  ? 301 ALA A CA    1 
ATOM   1207 C C     . ALA A 1 301 ? 151.849 174.551 126.058 1.00 30.26  ? 301 ALA A C     1 
ATOM   1208 O O     . ALA A 1 301 ? 150.864 173.912 126.444 1.00 27.62  ? 301 ALA A O     1 
ATOM   1209 C CB    . ALA A 1 301 ? 153.760 174.927 127.640 1.00 30.74  ? 301 ALA A CB    1 
ATOM   1210 N N     . TYR A 1 302 ? 151.737 175.640 125.294 1.00 33.13  ? 302 TYR A N     1 
ATOM   1211 C CA    . TYR A 1 302 ? 150.425 176.101 124.849 1.00 34.18  ? 302 TYR A CA    1 
ATOM   1212 C C     . TYR A 1 302 ? 149.756 175.075 123.943 1.00 33.78  ? 302 TYR A C     1 
ATOM   1213 O O     . TYR A 1 302 ? 148.554 174.815 124.071 1.00 34.38  ? 302 TYR A O     1 
ATOM   1214 C CB    . TYR A 1 302 ? 150.556 177.446 124.135 1.00 34.85  ? 302 TYR A CB    1 
ATOM   1215 C CG    . TYR A 1 302 ? 149.230 178.103 123.825 1.00 34.23  ? 302 TYR A CG    1 
ATOM   1216 C CD1   . TYR A 1 302 ? 148.527 178.787 124.807 1.00 34.15  ? 302 TYR A CD1   1 
ATOM   1217 C CD2   . TYR A 1 302 ? 148.682 178.039 122.551 1.00 33.51  ? 302 TYR A CD2   1 
ATOM   1218 C CE1   . TYR A 1 302 ? 147.315 179.389 124.530 1.00 34.18  ? 302 TYR A CE1   1 
ATOM   1219 C CE2   . TYR A 1 302 ? 147.470 178.637 122.265 1.00 34.19  ? 302 TYR A CE2   1 
ATOM   1220 C CZ    . TYR A 1 302 ? 146.792 179.311 123.257 1.00 33.92  ? 302 TYR A CZ    1 
ATOM   1221 O OH    . TYR A 1 302 ? 145.585 179.908 122.976 1.00 33.79  ? 302 TYR A OH    1 
ATOM   1222 N N     . ILE A 1 303 ? 150.517 174.484 123.018 1.00 29.14  ? 303 ILE A N     1 
ATOM   1223 C CA    . ILE A 1 303 ? 149.955 173.471 122.127 1.00 28.33  ? 303 ILE A CA    1 
ATOM   1224 C C     . ILE A 1 303 ? 149.503 172.252 122.921 1.00 27.38  ? 303 ILE A C     1 
ATOM   1225 O O     . ILE A 1 303 ? 148.421 171.700 122.680 1.00 26.06  ? 303 ILE A O     1 
ATOM   1226 C CB    . ILE A 1 303 ? 150.976 173.093 121.037 1.00 29.12  ? 303 ILE A CB    1 
ATOM   1227 C CG1   . ILE A 1 303 ? 151.098 174.217 120.007 1.00 31.12  ? 303 ILE A CG1   1 
ATOM   1228 C CG2   . ILE A 1 303 ? 150.582 171.791 120.357 1.00 26.82  ? 303 ILE A CG2   1 
ATOM   1229 C CD1   . ILE A 1 303 ? 152.338 174.123 119.149 1.00 26.62  ? 303 ILE A CD1   1 
ATOM   1230 N N     . GLN A 1 304 ? 150.322 171.812 123.880 1.00 28.44  ? 304 GLN A N     1 
ATOM   1231 C CA    . GLN A 1 304 ? 149.954 170.662 124.699 1.00 22.29  ? 304 GLN A CA    1 
ATOM   1232 C C     . GLN A 1 304 ? 148.699 170.944 125.516 1.00 28.18  ? 304 GLN A C     1 
ATOM   1233 O O     . GLN A 1 304 ? 147.813 170.088 125.622 1.00 31.68  ? 304 GLN A O     1 
ATOM   1234 C CB    . GLN A 1 304 ? 151.120 170.278 125.610 1.00 21.56  ? 304 GLN A CB    1 
ATOM   1235 C CG    . GLN A 1 304 ? 150.727 169.453 126.823 1.00 25.80  ? 304 GLN A CG    1 
ATOM   1236 C CD    . GLN A 1 304 ? 151.924 169.041 127.655 1.00 28.28  ? 304 GLN A CD    1 
ATOM   1237 O OE1   . GLN A 1 304 ? 153.051 169.458 127.390 1.00 29.93  ? 304 GLN A OE1   1 
ATOM   1238 N NE2   . GLN A 1 304 ? 151.685 168.218 128.670 1.00 25.75  ? 304 GLN A NE2   1 
ATOM   1239 N N     . CYS A 1 305 ? 148.602 172.143 126.097 1.00 29.89  ? 305 CYS A N     1 
ATOM   1240 C CA    . CYS A 1 305 ? 147.413 172.501 126.863 1.00 28.68  ? 305 CYS A CA    1 
ATOM   1241 C C     . CYS A 1 305 ? 146.180 172.564 125.971 1.00 29.84  ? 305 CYS A C     1 
ATOM   1242 O O     . CYS A 1 305 ? 145.095 172.123 126.368 1.00 28.87  ? 305 CYS A O     1 
ATOM   1243 C CB    . CYS A 1 305 ? 147.629 173.835 127.577 1.00 28.24  ? 305 CYS A CB    1 
ATOM   1244 S SG    . CYS A 1 305 ? 148.827 173.771 128.930 1.00 42.62  ? 305 CYS A SG    1 
ATOM   1245 N N     . GLN A 1 306 ? 146.323 173.112 124.761 1.00 28.15  ? 306 GLN A N     1 
ATOM   1246 C CA    . GLN A 1 306 ? 145.196 173.168 123.837 1.00 27.15  ? 306 GLN A CA    1 
ATOM   1247 C C     . GLN A 1 306 ? 144.733 171.770 123.448 1.00 24.27  ? 306 GLN A C     1 
ATOM   1248 O O     . GLN A 1 306 ? 143.528 171.512 123.347 1.00 25.11  ? 306 GLN A O     1 
ATOM   1249 C CB    . GLN A 1 306 ? 145.575 173.975 122.595 1.00 24.83  ? 306 GLN A CB    1 
ATOM   1250 N N     . PHE A 1 307 ? 145.678 170.856 123.216 1.00 24.20  ? 307 PHE A N     1 
ATOM   1251 C CA    . PHE A 1 307 ? 145.306 169.484 122.881 1.00 23.37  ? 307 PHE A CA    1 
ATOM   1252 C C     . PHE A 1 307 ? 144.637 168.785 124.059 1.00 25.18  ? 307 PHE A C     1 
ATOM   1253 O O     . PHE A 1 307 ? 143.660 168.049 123.876 1.00 27.57  ? 307 PHE A O     1 
ATOM   1254 C CB    . PHE A 1 307 ? 146.532 168.703 122.415 1.00 17.63  ? 307 PHE A CB    1 
ATOM   1255 C CG    . PHE A 1 307 ? 146.679 168.652 120.923 1.00 20.25  ? 307 PHE A CG    1 
ATOM   1256 C CD1   . PHE A 1 307 ? 145.912 167.779 120.171 1.00 17.68  ? 307 PHE A CD1   1 
ATOM   1257 C CD2   . PHE A 1 307 ? 147.576 169.479 120.272 1.00 21.08  ? 307 PHE A CD2   1 
ATOM   1258 C CE1   . PHE A 1 307 ? 146.039 167.730 118.799 1.00 18.35  ? 307 PHE A CE1   1 
ATOM   1259 C CE2   . PHE A 1 307 ? 147.708 169.434 118.898 1.00 21.43  ? 307 PHE A CE2   1 
ATOM   1260 C CZ    . PHE A 1 307 ? 146.938 168.559 118.162 1.00 21.40  ? 307 PHE A CZ    1 
ATOM   1261 N N     . GLU A 1 308 ? 145.146 168.998 125.274 1.00 23.27  ? 308 GLU A N     1 
ATOM   1262 C CA    . GLU A 1 308 ? 144.536 168.387 126.450 1.00 21.48  ? 308 GLU A CA    1 
ATOM   1263 C C     . GLU A 1 308 ? 143.171 168.983 126.771 1.00 23.26  ? 308 GLU A C     1 
ATOM   1264 O O     . GLU A 1 308 ? 142.346 168.307 127.394 1.00 25.20  ? 308 GLU A O     1 
ATOM   1265 C CB    . GLU A 1 308 ? 145.462 168.526 127.659 1.00 23.78  ? 308 GLU A CB    1 
ATOM   1266 C CG    . GLU A 1 308 ? 146.762 167.749 127.538 1.00 20.03  ? 308 GLU A CG    1 
ATOM   1267 C CD    . GLU A 1 308 ? 147.476 167.595 128.866 1.00 23.07  ? 308 GLU A CD    1 
ATOM   1268 O OE1   . GLU A 1 308 ? 148.290 168.477 129.211 1.00 20.99  ? 308 GLU A OE1   1 
ATOM   1269 O OE2   . GLU A 1 308 ? 147.223 166.592 129.565 1.00 25.26  ? 308 GLU A OE2   1 
ATOM   1270 N N     . ASP A 1 309 ? 142.917 170.228 126.365 1.00 22.82  ? 309 ASP A N     1 
ATOM   1271 C CA    . ASP A 1 309 ? 141.620 170.851 126.600 1.00 22.62  ? 309 ASP A CA    1 
ATOM   1272 C C     . ASP A 1 309 ? 140.515 170.262 125.734 1.00 23.38  ? 309 ASP A C     1 
ATOM   1273 O O     . ASP A 1 309 ? 139.342 170.574 125.963 1.00 24.27  ? 309 ASP A O     1 
ATOM   1274 C CB    . ASP A 1 309 ? 141.713 172.359 126.361 1.00 23.12  ? 309 ASP A CB    1 
ATOM   1275 N N     . LEU A 1 310 ? 140.855 169.428 124.751 1.00 23.98  ? 310 LEU A N     1 
ATOM   1276 C CA    . LEU A 1 310 ? 139.854 168.783 123.913 1.00 22.32  ? 310 LEU A CA    1 
ATOM   1277 C C     . LEU A 1 310 ? 139.199 167.587 124.591 1.00 23.42  ? 310 LEU A C     1 
ATOM   1278 O O     . LEU A 1 310 ? 138.261 167.014 124.027 1.00 22.04  ? 310 LEU A O     1 
ATOM   1279 C CB    . LEU A 1 310 ? 140.482 168.341 122.590 1.00 19.43  ? 310 LEU A CB    1 
ATOM   1280 C CG    . LEU A 1 310 ? 141.033 169.454 121.697 1.00 21.54  ? 310 LEU A CG    1 
ATOM   1281 C CD1   . LEU A 1 310 ? 141.869 168.873 120.570 1.00 19.83  ? 310 LEU A CD1   1 
ATOM   1282 C CD2   . LEU A 1 310 ? 139.903 170.307 121.144 1.00 25.24  ? 310 LEU A CD2   1 
ATOM   1283 N N     . ASN A 1 311 ? 139.668 167.198 125.774 1.00 22.95  ? 311 ASN A N     1 
ATOM   1284 C CA    . ASN A 1 311 ? 139.106 166.063 126.492 1.00 22.52  ? 311 ASN A CA    1 
ATOM   1285 C C     . ASN A 1 311 ? 137.907 166.519 127.315 1.00 27.22  ? 311 ASN A C     1 
ATOM   1286 O O     . ASN A 1 311 ? 138.050 167.330 128.236 1.00 27.40  ? 311 ASN A O     1 
ATOM   1287 C CB    . ASN A 1 311 ? 140.168 165.431 127.389 1.00 18.11  ? 311 ASN A CB    1 
ATOM   1288 C CG    . ASN A 1 311 ? 139.716 164.116 127.994 1.00 25.99  ? 311 ASN A CG    1 
ATOM   1289 O OD1   . ASN A 1 311 ? 138.648 163.600 127.666 1.00 30.17  ? 311 ASN A OD1   1 
ATOM   1290 N ND2   . ASN A 1 311 ? 140.531 163.567 128.887 1.00 22.98  ? 311 ASN A ND2   1 
ATOM   1291 N N     . LYS A 1 312 ? 136.726 165.998 126.984 1.00 26.52  ? 312 LYS A N     1 
ATOM   1292 C CA    . LYS A 1 312 ? 135.511 166.304 127.726 1.00 24.49  ? 312 LYS A CA    1 
ATOM   1293 C C     . LYS A 1 312 ? 135.311 165.400 128.935 1.00 28.09  ? 312 LYS A C     1 
ATOM   1294 O O     . LYS A 1 312 ? 134.381 165.630 129.714 1.00 32.16  ? 312 LYS A O     1 
ATOM   1295 C CB    . LYS A 1 312 ? 134.288 166.194 126.807 1.00 21.94  ? 312 LYS A CB    1 
ATOM   1296 C CG    . LYS A 1 312 ? 134.421 166.953 125.498 1.00 27.44  ? 312 LYS A CG    1 
ATOM   1297 C CD    . LYS A 1 312 ? 134.599 168.442 125.731 1.00 27.08  ? 312 LYS A CD    1 
ATOM   1298 C CE    . LYS A 1 312 ? 134.403 169.224 124.443 1.00 27.52  ? 312 LYS A CE    1 
ATOM   1299 N NZ    . LYS A 1 312 ? 135.447 168.897 123.433 1.00 26.89  ? 312 LYS A NZ    1 
ATOM   1300 N N     . ARG A 1 313 ? 136.155 164.386 129.106 1.00 25.28  ? 313 ARG A N     1 
ATOM   1301 C CA    . ARG A 1 313 ? 136.048 163.407 130.184 1.00 24.06  ? 313 ARG A CA    1 
ATOM   1302 C C     . ARG A 1 313 ? 137.377 163.285 130.915 1.00 26.54  ? 313 ARG A C     1 
ATOM   1303 O O     . ARG A 1 313 ? 137.906 162.191 131.124 1.00 26.50  ? 313 ARG A O     1 
ATOM   1304 C CB    . ARG A 1 313 ? 135.597 162.052 129.645 1.00 25.54  ? 313 ARG A CB    1 
ATOM   1305 C CG    . ARG A 1 313 ? 134.506 162.138 128.591 1.00 28.29  ? 313 ARG A CG    1 
ATOM   1306 C CD    . ARG A 1 313 ? 134.176 160.774 128.018 1.00 26.11  ? 313 ARG A CD    1 
ATOM   1307 N NE    . ARG A 1 313 ? 133.475 160.878 126.744 1.00 32.24  ? 313 ARG A NE    1 
ATOM   1308 C CZ    . ARG A 1 313 ? 132.157 160.956 126.618 1.00 32.79  ? 313 ARG A CZ    1 
ATOM   1309 N NH1   . ARG A 1 313 ? 131.360 160.945 127.673 1.00 27.46  ? 313 ARG A NH1   1 
ATOM   1310 N NH2   . ARG A 1 313 ? 131.626 161.048 125.402 1.00 29.82  ? 313 ARG A NH2   1 
ATOM   1311 N N     . LYS A 1 314 ? 137.942 164.433 131.303 1.00 25.95  ? 314 LYS A N     1 
ATOM   1312 C CA    . LYS A 1 314 ? 139.253 164.446 131.947 1.00 27.97  ? 314 LYS A CA    1 
ATOM   1313 C C     . LYS A 1 314 ? 139.264 163.641 133.240 1.00 25.79  ? 314 LYS A C     1 
ATOM   1314 O O     . LYS A 1 314 ? 140.312 163.119 133.635 1.00 28.13  ? 314 LYS A O     1 
ATOM   1315 C CB    . LYS A 1 314 ? 139.684 165.887 132.224 1.00 26.90  ? 314 LYS A CB    1 
ATOM   1316 C CG    . LYS A 1 314 ? 139.839 166.743 130.979 1.00 29.63  ? 314 LYS A CG    1 
ATOM   1317 C CD    . LYS A 1 314 ? 140.327 168.139 131.328 1.00 26.19  ? 314 LYS A CD    1 
ATOM   1318 C CE    . LYS A 1 314 ? 140.497 168.993 130.083 1.00 26.98  ? 314 LYS A CE    1 
ATOM   1319 N NZ    . LYS A 1 314 ? 139.187 169.308 129.448 1.00 26.12  ? 314 LYS A NZ    1 
ATOM   1320 N N     . ASP A 1 315 ? 138.118 163.536 133.916 1.00 25.17  ? 315 ASP A N     1 
ATOM   1321 C CA    . ASP A 1 315 ? 138.064 162.779 135.162 1.00 28.15  ? 315 ASP A CA    1 
ATOM   1322 C C     . ASP A 1 315 ? 138.289 161.291 134.924 1.00 26.09  ? 315 ASP A C     1 
ATOM   1323 O O     . ASP A 1 315 ? 138.991 160.632 135.699 1.00 25.40  ? 315 ASP A O     1 
ATOM   1324 C CB    . ASP A 1 315 ? 136.724 163.014 135.860 1.00 28.32  ? 315 ASP A CB    1 
ATOM   1325 N N     . THR A 1 316 ? 137.705 160.743 133.858 1.00 22.63  ? 316 THR A N     1 
ATOM   1326 C CA    . THR A 1 316 ? 137.760 159.312 133.594 1.00 25.47  ? 316 THR A CA    1 
ATOM   1327 C C     . THR A 1 316 ? 138.847 158.912 132.605 1.00 26.95  ? 316 THR A C     1 
ATOM   1328 O O     . THR A 1 316 ? 139.138 157.718 132.483 1.00 26.19  ? 316 THR A O     1 
ATOM   1329 C CB    . THR A 1 316 ? 136.404 158.818 133.072 1.00 24.40  ? 316 THR A CB    1 
ATOM   1330 N N     . LYS A 1 317 ? 139.453 159.866 131.902 1.00 19.20  ? 317 LYS A N     1 
ATOM   1331 C CA    . LYS A 1 317 ? 140.447 159.568 130.882 1.00 13.82  ? 317 LYS A CA    1 
ATOM   1332 C C     . LYS A 1 317 ? 141.697 160.402 131.121 1.00 16.82  ? 317 LYS A C     1 
ATOM   1333 O O     . LYS A 1 317 ? 141.610 161.568 131.516 1.00 19.46  ? 317 LYS A O     1 
ATOM   1334 C CB    . LYS A 1 317 ? 139.891 159.835 129.476 1.00 17.17  ? 317 LYS A CB    1 
ATOM   1335 C CG    . LYS A 1 317 ? 140.892 159.630 128.353 1.00 18.26  ? 317 LYS A CG    1 
ATOM   1336 C CD    . LYS A 1 317 ? 140.436 160.314 127.080 1.00 16.30  ? 317 LYS A CD    1 
ATOM   1337 C CE    . LYS A 1 317 ? 139.243 159.603 126.469 1.00 14.70  ? 317 LYS A CE    1 
ATOM   1338 N NZ    . LYS A 1 317 ? 139.664 158.531 125.525 1.00 16.77  ? 317 LYS A NZ    1 
ATOM   1339 N N     . GLU A 1 318 ? 142.857 159.798 130.877 1.00 10.99  ? 318 GLU A N     1 
ATOM   1340 C CA    . GLU A 1 318 ? 144.144 160.459 131.030 1.00 9.89   ? 318 GLU A CA    1 
ATOM   1341 C C     . GLU A 1 318 ? 144.840 160.550 129.680 1.00 5.16   ? 318 GLU A C     1 
ATOM   1342 O O     . GLU A 1 318 ? 144.768 159.620 128.871 1.00 9.72   ? 318 GLU A O     1 
ATOM   1343 C CB    . GLU A 1 318 ? 145.038 159.713 132.026 1.00 8.35   ? 318 GLU A CB    1 
ATOM   1344 N N     . ILE A 1 319 ? 145.509 161.673 129.442 1.00 6.16   ? 319 ILE A N     1 
ATOM   1345 C CA    . ILE A 1 319 ? 146.268 161.904 128.218 1.00 6.95   ? 319 ILE A CA    1 
ATOM   1346 C C     . ILE A 1 319 ? 147.739 162.016 128.595 1.00 10.43  ? 319 ILE A C     1 
ATOM   1347 O O     . ILE A 1 319 ? 148.114 162.857 129.420 1.00 17.70  ? 319 ILE A O     1 
ATOM   1348 C CB    . ILE A 1 319 ? 145.788 163.162 127.478 1.00 4.12   ? 319 ILE A CB    1 
ATOM   1349 C CG1   . ILE A 1 319 ? 144.379 162.945 126.922 1.00 2.80   ? 319 ILE A CG1   1 
ATOM   1350 C CG2   . ILE A 1 319 ? 146.753 163.527 126.362 1.00 4.19   ? 319 ILE A CG2   1 
ATOM   1351 C CD1   . ILE A 1 319 ? 143.703 164.215 126.464 1.00 15.13  ? 319 ILE A CD1   1 
ATOM   1352 N N     . TYR A 1 320 ? 148.569 161.169 127.991 1.00 2.67   ? 320 TYR A N     1 
ATOM   1353 C CA    . TYR A 1 320 ? 150.000 161.114 128.287 1.00 1.01   ? 320 TYR A CA    1 
ATOM   1354 C C     . TYR A 1 320 ? 150.746 161.820 127.160 1.00 3.41   ? 320 TYR A C     1 
ATOM   1355 O O     . TYR A 1 320 ? 151.179 161.197 126.190 1.00 15.92  ? 320 TYR A O     1 
ATOM   1356 C CB    . TYR A 1 320 ? 150.465 159.671 128.449 1.00 1.94   ? 320 TYR A CB    1 
ATOM   1357 C CG    . TYR A 1 320 ? 149.726 158.896 129.515 1.00 3.70   ? 320 TYR A CG    1 
ATOM   1358 C CD1   . TYR A 1 320 ? 150.174 158.884 130.828 1.00 9.07   ? 320 TYR A CD1   1 
ATOM   1359 C CD2   . TYR A 1 320 ? 148.583 158.171 129.206 1.00 7.07   ? 320 TYR A CD2   1 
ATOM   1360 C CE1   . TYR A 1 320 ? 149.504 158.174 131.804 1.00 7.66   ? 320 TYR A CE1   1 
ATOM   1361 C CE2   . TYR A 1 320 ? 147.906 157.459 130.175 1.00 7.54   ? 320 TYR A CE2   1 
ATOM   1362 C CZ    . TYR A 1 320 ? 148.371 157.464 131.472 1.00 8.56   ? 320 TYR A CZ    1 
ATOM   1363 O OH    . TYR A 1 320 ? 147.699 156.755 132.440 1.00 14.35  ? 320 TYR A OH    1 
ATOM   1364 N N     . THR A 1 321 ? 150.898 163.134 127.293 1.00 1.72   ? 321 THR A N     1 
ATOM   1365 C CA    . THR A 1 321 ? 151.589 163.924 126.284 1.00 5.78   ? 321 THR A CA    1 
ATOM   1366 C C     . THR A 1 321 ? 153.097 163.752 126.420 1.00 11.16  ? 321 THR A C     1 
ATOM   1367 O O     . THR A 1 321 ? 153.644 163.844 127.523 1.00 18.45  ? 321 THR A O     1 
ATOM   1368 C CB    . THR A 1 321 ? 151.212 165.399 126.410 1.00 6.84   ? 321 THR A CB    1 
ATOM   1369 O OG1   . THR A 1 321 ? 149.791 165.543 126.288 1.00 9.55   ? 321 THR A OG1   1 
ATOM   1370 C CG2   . THR A 1 321 ? 151.891 166.218 125.324 1.00 10.11  ? 321 THR A CG2   1 
ATOM   1371 N N     . HIS A 1 322 ? 153.766 163.501 125.297 1.00 11.00  ? 322 HIS A N     1 
ATOM   1372 C CA    . HIS A 1 322 ? 155.213 163.354 125.267 1.00 10.79  ? 322 HIS A CA    1 
ATOM   1373 C C     . HIS A 1 322 ? 155.768 164.099 124.063 1.00 15.03  ? 322 HIS A C     1 
ATOM   1374 O O     . HIS A 1 322 ? 155.081 164.280 123.055 1.00 26.58  ? 322 HIS A O     1 
ATOM   1375 C CB    . HIS A 1 322 ? 155.634 161.879 125.213 1.00 10.88  ? 322 HIS A CB    1 
ATOM   1376 C CG    . HIS A 1 322 ? 157.093 161.657 125.468 1.00 17.65  ? 322 HIS A CG    1 
ATOM   1377 N ND1   . HIS A 1 322 ? 157.838 160.730 124.771 1.00 18.76  ? 322 HIS A ND1   1 
ATOM   1378 C CD2   . HIS A 1 322 ? 157.944 162.241 126.344 1.00 17.64  ? 322 HIS A CD2   1 
ATOM   1379 C CE1   . HIS A 1 322 ? 159.085 160.754 125.206 1.00 14.44  ? 322 HIS A CE1   1 
ATOM   1380 N NE2   . HIS A 1 322 ? 159.176 161.662 126.161 1.00 16.37  ? 322 HIS A NE2   1 
ATOM   1381 N N     . PHE A 1 323 ? 157.021 164.528 124.177 1.00 17.48  ? 323 PHE A N     1 
ATOM   1382 C CA    . PHE A 1 323 ? 157.710 165.255 123.120 1.00 20.28  ? 323 PHE A CA    1 
ATOM   1383 C C     . PHE A 1 323 ? 158.829 164.393 122.552 1.00 24.92  ? 323 PHE A C     1 
ATOM   1384 O O     . PHE A 1 323 ? 159.686 163.909 123.299 1.00 25.12  ? 323 PHE A O     1 
ATOM   1385 C CB    . PHE A 1 323 ? 158.276 166.577 123.643 1.00 20.82  ? 323 PHE A CB    1 
ATOM   1386 C CG    . PHE A 1 323 ? 157.234 167.633 123.875 1.00 21.75  ? 323 PHE A CG    1 
ATOM   1387 C CD1   . PHE A 1 323 ? 156.851 168.482 122.852 1.00 21.58  ? 323 PHE A CD1   1 
ATOM   1388 C CD2   . PHE A 1 323 ? 156.639 167.778 125.117 1.00 24.67  ? 323 PHE A CD2   1 
ATOM   1389 C CE1   . PHE A 1 323 ? 155.895 169.455 123.062 1.00 22.80  ? 323 PHE A CE1   1 
ATOM   1390 C CE2   . PHE A 1 323 ? 155.680 168.750 125.332 1.00 21.70  ? 323 PHE A CE2   1 
ATOM   1391 C CZ    . PHE A 1 323 ? 155.309 169.589 124.303 1.00 19.61  ? 323 PHE A CZ    1 
ATOM   1392 N N     . THR A 1 324 ? 158.816 164.205 121.235 1.00 28.18  ? 324 THR A N     1 
ATOM   1393 C CA    . THR A 1 324 ? 159.838 163.439 120.538 1.00 28.00  ? 324 THR A CA    1 
ATOM   1394 C C     . THR A 1 324 ? 160.272 164.195 119.291 1.00 32.03  ? 324 THR A C     1 
ATOM   1395 O O     . THR A 1 324 ? 159.475 164.902 118.668 1.00 30.92  ? 324 THR A O     1 
ATOM   1396 C CB    . THR A 1 324 ? 159.333 162.043 120.149 1.00 24.25  ? 324 THR A CB    1 
ATOM   1397 N N     . CYS A 1 325 ? 161.547 164.049 118.932 1.00 36.67  ? 325 CYS A N     1 
ATOM   1398 C CA    . CYS A 1 325 ? 162.093 164.710 117.754 1.00 37.18  ? 325 CYS A CA    1 
ATOM   1399 C C     . CYS A 1 325 ? 162.510 163.719 116.675 1.00 38.41  ? 325 CYS A C     1 
ATOM   1400 O O     . CYS A 1 325 ? 161.990 163.772 115.556 1.00 39.33  ? 325 CYS A O     1 
ATOM   1401 C CB    . CYS A 1 325 ? 163.284 165.594 118.154 1.00 37.17  ? 325 CYS A CB    1 
ATOM   1402 N N     . ALA A 1 326 ? 163.427 162.802 116.985 1.00 42.22  ? 326 ALA A N     1 
ATOM   1403 C CA    . ALA A 1 326 ? 163.900 161.832 116.004 1.00 43.46  ? 326 ALA A CA    1 
ATOM   1404 C C     . ALA A 1 326 ? 164.679 160.702 116.665 1.00 44.63  ? 326 ALA A C     1 
ATOM   1405 O O     . ALA A 1 326 ? 165.653 160.953 117.382 1.00 43.25  ? 326 ALA A O     1 
ATOM   1406 C CB    . ALA A 1 326 ? 164.773 162.515 114.949 1.00 40.58  ? 326 ALA A CB    1 
ATOM   1407 N N     . THR A 1 327 ? 164.258 159.459 116.418 1.00 46.17  ? 327 THR A N     1 
ATOM   1408 C CA    . THR A 1 327 ? 164.983 158.265 116.862 1.00 47.14  ? 327 THR A CA    1 
ATOM   1409 C C     . THR A 1 327 ? 165.268 158.302 118.362 1.00 46.19  ? 327 THR A C     1 
ATOM   1410 O O     . THR A 1 327 ? 166.356 157.945 118.819 1.00 46.36  ? 327 THR A O     1 
ATOM   1411 C CB    . THR A 1 327 ? 166.279 158.084 116.069 1.00 43.53  ? 327 THR A CB    1 
ATOM   1412 N N     . ASP A 1 328 ? 164.280 158.739 119.137 1.00 39.52  ? 328 ASP A N     1 
ATOM   1413 C CA    . ASP A 1 328 ? 164.431 158.810 120.584 1.00 40.37  ? 328 ASP A CA    1 
ATOM   1414 C C     . ASP A 1 328 ? 164.101 157.461 121.210 1.00 40.46  ? 328 ASP A C     1 
ATOM   1415 O O     . ASP A 1 328 ? 163.031 156.895 120.961 1.00 40.02  ? 328 ASP A O     1 
ATOM   1416 C CB    . ASP A 1 328 ? 163.532 159.902 121.162 1.00 39.32  ? 328 ASP A CB    1 
ATOM   1417 C CG    . ASP A 1 328 ? 163.679 161.222 120.432 1.00 41.61  ? 328 ASP A CG    1 
ATOM   1418 O OD1   . ASP A 1 328 ? 164.826 161.682 120.259 1.00 42.53  ? 328 ASP A OD1   1 
ATOM   1419 O OD2   . ASP A 1 328 ? 162.647 161.799 120.030 1.00 39.48  ? 328 ASP A OD2   1 
ATOM   1420 N N     . THR A 1 329 ? 165.024 156.946 122.022 1.00 36.21  ? 329 THR A N     1 
ATOM   1421 C CA    . THR A 1 329 ? 164.829 155.662 122.682 1.00 35.90  ? 329 THR A CA    1 
ATOM   1422 C C     . THR A 1 329 ? 163.931 155.754 123.908 1.00 35.53  ? 329 THR A C     1 
ATOM   1423 O O     . THR A 1 329 ? 163.515 154.712 124.428 1.00 31.56  ? 329 THR A O     1 
ATOM   1424 C CB    . THR A 1 329 ? 166.179 155.065 123.086 1.00 32.71  ? 329 THR A CB    1 
ATOM   1425 N N     . LYS A 1 330 ? 163.623 156.960 124.380 1.00 28.12  ? 330 LYS A N     1 
ATOM   1426 C CA    . LYS A 1 330 ? 162.756 157.138 125.536 1.00 24.34  ? 330 LYS A CA    1 
ATOM   1427 C C     . LYS A 1 330 ? 161.276 157.077 125.184 1.00 28.05  ? 330 LYS A C     1 
ATOM   1428 O O     . LYS A 1 330 ? 160.441 157.031 126.095 1.00 30.12  ? 330 LYS A O     1 
ATOM   1429 C CB    . LYS A 1 330 ? 163.060 158.474 126.224 1.00 24.54  ? 330 LYS A CB    1 
ATOM   1430 N N     . ASN A 1 331 ? 160.932 157.080 123.894 1.00 25.53  ? 331 ASN A N     1 
ATOM   1431 C CA    . ASN A 1 331 ? 159.531 156.981 123.500 1.00 21.57  ? 331 ASN A CA    1 
ATOM   1432 C C     . ASN A 1 331 ? 158.937 155.641 123.911 1.00 20.35  ? 331 ASN A C     1 
ATOM   1433 O O     . ASN A 1 331 ? 157.802 155.577 124.400 1.00 27.61  ? 331 ASN A O     1 
ATOM   1434 C CB    . ASN A 1 331 ? 159.397 157.188 121.992 1.00 21.43  ? 331 ASN A CB    1 
ATOM   1435 C CG    . ASN A 1 331 ? 159.744 158.599 121.566 1.00 23.09  ? 331 ASN A CG    1 
ATOM   1436 O OD1   . ASN A 1 331 ? 159.582 159.547 122.333 1.00 28.76  ? 331 ASN A OD1   1 
ATOM   1437 N ND2   . ASN A 1 331 ? 160.227 158.745 120.338 1.00 23.57  ? 331 ASN A ND2   1 
ATOM   1438 N N     . VAL A 1 332 ? 159.693 154.558 123.722 1.00 16.93  ? 332 VAL A N     1 
ATOM   1439 C CA    . VAL A 1 332 ? 159.212 153.240 124.122 1.00 16.39  ? 332 VAL A CA    1 
ATOM   1440 C C     . VAL A 1 332 ? 159.047 153.171 125.634 1.00 20.69  ? 332 VAL A C     1 
ATOM   1441 O O     . VAL A 1 332 ? 158.103 152.556 126.139 1.00 21.05  ? 332 VAL A O     1 
ATOM   1442 C CB    . VAL A 1 332 ? 160.159 152.144 123.604 1.00 21.26  ? 332 VAL A CB    1 
ATOM   1443 C CG1   . VAL A 1 332 ? 159.507 150.777 123.737 1.00 21.52  ? 332 VAL A CG1   1 
ATOM   1444 C CG2   . VAL A 1 332 ? 160.545 152.417 122.160 1.00 25.44  ? 332 VAL A CG2   1 
ATOM   1445 N N     . GLN A 1 333 ? 159.958 153.800 126.382 1.00 21.18  ? 333 GLN A N     1 
ATOM   1446 C CA    . GLN A 1 333 ? 159.829 153.827 127.836 1.00 15.03  ? 333 GLN A CA    1 
ATOM   1447 C C     . GLN A 1 333 ? 158.597 154.613 128.272 1.00 17.03  ? 333 GLN A C     1 
ATOM   1448 O O     . GLN A 1 333 ? 157.895 154.209 129.207 1.00 18.91  ? 333 GLN A O     1 
ATOM   1449 C CB    . GLN A 1 333 ? 161.092 154.416 128.464 1.00 15.22  ? 333 GLN A CB    1 
ATOM   1450 C CG    . GLN A 1 333 ? 161.106 154.368 129.982 1.00 19.14  ? 333 GLN A CG    1 
ATOM   1451 C CD    . GLN A 1 333 ? 161.115 152.950 130.517 1.00 23.57  ? 333 GLN A CD    1 
ATOM   1452 O OE1   . GLN A 1 333 ? 161.898 152.112 130.071 1.00 24.53  ? 333 GLN A OE1   1 
ATOM   1453 N NE2   . GLN A 1 333 ? 160.241 152.674 131.477 1.00 18.28  ? 333 GLN A NE2   1 
ATOM   1454 N N     . PHE A 1 334 ? 158.325 155.743 127.616 1.00 17.20  ? 334 PHE A N     1 
ATOM   1455 C CA    . PHE A 1 334 ? 157.125 156.512 127.934 1.00 14.59  ? 334 PHE A CA    1 
ATOM   1456 C C     . PHE A 1 334 ? 155.866 155.707 127.640 1.00 14.55  ? 334 PHE A C     1 
ATOM   1457 O O     . PHE A 1 334 ? 154.917 155.703 128.437 1.00 14.39  ? 334 PHE A O     1 
ATOM   1458 C CB    . PHE A 1 334 ? 157.122 157.823 127.149 1.00 11.05  ? 334 PHE A CB    1 
ATOM   1459 C CG    . PHE A 1 334 ? 156.021 158.764 127.543 1.00 14.42  ? 334 PHE A CG    1 
ATOM   1460 C CD1   . PHE A 1 334 ? 156.198 159.662 128.582 1.00 17.32  ? 334 PHE A CD1   1 
ATOM   1461 C CD2   . PHE A 1 334 ? 154.810 158.756 126.871 1.00 12.54  ? 334 PHE A CD2   1 
ATOM   1462 C CE1   . PHE A 1 334 ? 155.187 160.528 128.946 1.00 14.35  ? 334 PHE A CE1   1 
ATOM   1463 C CE2   . PHE A 1 334 ? 153.798 159.619 127.232 1.00 10.48  ? 334 PHE A CE2   1 
ATOM   1464 C CZ    . PHE A 1 334 ? 153.987 160.507 128.270 1.00 15.81  ? 334 PHE A CZ    1 
ATOM   1465 N N     . VAL A 1 335 ? 155.842 155.017 126.497 1.00 13.77  ? 335 VAL A N     1 
ATOM   1466 C CA    . VAL A 1 335 ? 154.706 154.163 126.164 1.00 6.29   ? 335 VAL A CA    1 
ATOM   1467 C C     . VAL A 1 335 ? 154.549 153.063 127.204 1.00 14.55  ? 335 VAL A C     1 
ATOM   1468 O O     . VAL A 1 335 ? 153.433 152.748 127.631 1.00 19.33  ? 335 VAL A O     1 
ATOM   1469 C CB    . VAL A 1 335 ? 154.868 153.586 124.745 1.00 5.33   ? 335 VAL A CB    1 
ATOM   1470 C CG1   . VAL A 1 335 ? 153.853 152.482 124.495 1.00 8.97   ? 335 VAL A CG1   1 
ATOM   1471 C CG2   . VAL A 1 335 ? 154.725 154.685 123.710 1.00 10.75  ? 335 VAL A CG2   1 
ATOM   1472 N N     . PHE A 1 336 ? 155.664 152.461 127.626 1.00 15.52  ? 336 PHE A N     1 
ATOM   1473 C CA    . PHE A 1 336 ? 155.612 151.404 128.630 1.00 13.47  ? 336 PHE A CA    1 
ATOM   1474 C C     . PHE A 1 336 ? 155.042 151.918 129.945 1.00 15.42  ? 336 PHE A C     1 
ATOM   1475 O O     . PHE A 1 336 ? 154.211 151.252 130.568 1.00 17.99  ? 336 PHE A O     1 
ATOM   1476 C CB    . PHE A 1 336 ? 157.007 150.816 128.840 1.00 13.32  ? 336 PHE A CB    1 
ATOM   1477 C CG    . PHE A 1 336 ? 157.084 149.818 129.961 1.00 14.94  ? 336 PHE A CG    1 
ATOM   1478 C CD1   . PHE A 1 336 ? 156.734 148.495 129.753 1.00 14.57  ? 336 PHE A CD1   1 
ATOM   1479 C CD2   . PHE A 1 336 ? 157.516 150.201 131.220 1.00 13.99  ? 336 PHE A CD2   1 
ATOM   1480 C CE1   . PHE A 1 336 ? 156.806 147.576 130.781 1.00 12.64  ? 336 PHE A CE1   1 
ATOM   1481 C CE2   . PHE A 1 336 ? 157.589 149.286 132.251 1.00 15.32  ? 336 PHE A CE2   1 
ATOM   1482 C CZ    . PHE A 1 336 ? 157.234 147.972 132.031 1.00 16.46  ? 336 PHE A CZ    1 
ATOM   1483 N N     . ASP A 1 337 ? 155.478 153.099 130.385 1.00 13.12  ? 337 ASP A N     1 
ATOM   1484 C CA    . ASP A 1 337 ? 154.952 153.661 131.627 1.00 13.00  ? 337 ASP A CA    1 
ATOM   1485 C C     . ASP A 1 337 ? 153.459 153.949 131.516 1.00 13.62  ? 337 ASP A C     1 
ATOM   1486 O O     . ASP A 1 337 ? 152.683 153.634 132.431 1.00 20.04  ? 337 ASP A O     1 
ATOM   1487 C CB    . ASP A 1 337 ? 155.717 154.933 131.991 1.00 13.88  ? 337 ASP A CB    1 
ATOM   1488 C CG    . ASP A 1 337 ? 157.184 154.671 132.267 1.00 19.48  ? 337 ASP A CG    1 
ATOM   1489 O OD1   . ASP A 1 337 ? 157.561 153.489 132.410 1.00 20.10  ? 337 ASP A OD1   1 
ATOM   1490 O OD2   . ASP A 1 337 ? 157.959 155.647 132.340 1.00 20.39  ? 337 ASP A OD2   1 
ATOM   1491 N N     . ALA A 1 338 ? 153.037 154.543 130.396 1.00 7.22   ? 338 ALA A N     1 
ATOM   1492 C CA    . ALA A 1 338 ? 151.624 154.863 130.217 1.00 2.63   ? 338 ALA A CA    1 
ATOM   1493 C C     . ALA A 1 338 ? 150.770 153.601 130.207 1.00 5.55   ? 338 ALA A C     1 
ATOM   1494 O O     . ALA A 1 338 ? 149.727 153.537 130.869 1.00 4.57   ? 338 ALA A O     1 
ATOM   1495 C CB    . ALA A 1 338 ? 151.428 155.660 128.928 1.00 8.98   ? 338 ALA A CB    1 
ATOM   1496 N N     . VAL A 1 339 ? 151.208 152.575 129.474 1.00 9.43   ? 339 VAL A N     1 
ATOM   1497 C CA    . VAL A 1 339 ? 150.419 151.350 129.404 1.00 8.43   ? 339 VAL A CA    1 
ATOM   1498 C C     . VAL A 1 339 ? 150.477 150.591 130.721 1.00 10.40  ? 339 VAL A C     1 
ATOM   1499 O O     . VAL A 1 339 ? 149.540 149.865 131.055 1.00 13.24  ? 339 VAL A O     1 
ATOM   1500 C CB    . VAL A 1 339 ? 150.865 150.465 128.225 1.00 10.91  ? 339 VAL A CB    1 
ATOM   1501 C CG1   . VAL A 1 339 ? 150.789 151.240 126.917 1.00 7.10   ? 339 VAL A CG1   1 
ATOM   1502 C CG2   . VAL A 1 339 ? 152.255 149.914 128.464 1.00 15.41  ? 339 VAL A CG2   1 
ATOM   1503 N N     . THR A 1 340 ? 151.556 150.738 131.493 1.00 9.65   ? 340 THR A N     1 
ATOM   1504 C CA    . THR A 1 340 ? 151.592 150.135 132.820 1.00 10.30  ? 340 THR A CA    1 
ATOM   1505 C C     . THR A 1 340 ? 150.553 150.770 133.733 1.00 11.23  ? 340 THR A C     1 
ATOM   1506 O O     . THR A 1 340 ? 149.825 150.065 134.445 1.00 13.55  ? 340 THR A O     1 
ATOM   1507 C CB    . THR A 1 340 ? 152.992 150.268 133.419 1.00 8.50   ? 340 THR A CB    1 
ATOM   1508 O OG1   . THR A 1 340 ? 153.914 149.478 132.660 1.00 14.54  ? 340 THR A OG1   1 
ATOM   1509 C CG2   . THR A 1 340 ? 153.005 149.798 134.863 1.00 14.19  ? 340 THR A CG2   1 
ATOM   1510 N N     . ASP A 1 341 ? 150.459 152.102 133.711 1.00 9.79   ? 341 ASP A N     1 
ATOM   1511 C CA    . ASP A 1 341 ? 149.420 152.773 134.487 1.00 7.63   ? 341 ASP A CA    1 
ATOM   1512 C C     . ASP A 1 341 ? 148.029 152.349 134.024 1.00 10.04  ? 341 ASP A C     1 
ATOM   1513 O O     . ASP A 1 341 ? 147.142 152.088 134.848 1.00 12.77  ? 341 ASP A O     1 
ATOM   1514 C CB    . ASP A 1 341 ? 149.583 154.289 134.386 1.00 6.90   ? 341 ASP A CB    1 
ATOM   1515 N N     . VAL A 1 342 ? 147.828 152.261 132.706 1.00 9.91   ? 342 VAL A N     1 
ATOM   1516 C CA    . VAL A 1 342 ? 146.531 151.854 132.169 1.00 4.38   ? 342 VAL A CA    1 
ATOM   1517 C C     . VAL A 1 342 ? 146.196 150.428 132.591 1.00 8.97   ? 342 VAL A C     1 
ATOM   1518 O O     . VAL A 1 342 ? 145.053 150.125 132.949 1.00 13.86  ? 342 VAL A O     1 
ATOM   1519 C CB    . VAL A 1 342 ? 146.515 152.009 130.637 1.00 8.38   ? 342 VAL A CB    1 
ATOM   1520 C CG1   . VAL A 1 342 ? 145.252 151.401 130.051 1.00 13.48  ? 342 VAL A CG1   1 
ATOM   1521 C CG2   . VAL A 1 342 ? 146.623 153.471 130.257 1.00 8.17   ? 342 VAL A CG2   1 
ATOM   1522 N N     . ILE A 1 343 ? 147.182 149.531 132.548 1.00 9.85   ? 343 ILE A N     1 
ATOM   1523 C CA    . ILE A 1 343 ? 146.960 148.137 132.916 1.00 11.99  ? 343 ILE A CA    1 
ATOM   1524 C C     . ILE A 1 343 ? 146.614 148.021 134.393 1.00 13.09  ? 343 ILE A C     1 
ATOM   1525 O O     . ILE A 1 343 ? 145.731 147.247 134.775 1.00 15.99  ? 343 ILE A O     1 
ATOM   1526 C CB    . ILE A 1 343 ? 148.195 147.292 132.551 1.00 10.90  ? 343 ILE A CB    1 
ATOM   1527 C CG1   . ILE A 1 343 ? 148.182 146.940 131.064 1.00 10.45  ? 343 ILE A CG1   1 
ATOM   1528 C CG2   . ILE A 1 343 ? 148.261 146.028 133.395 1.00 14.27  ? 343 ILE A CG2   1 
ATOM   1529 C CD1   . ILE A 1 343 ? 149.525 146.495 130.537 1.00 12.80  ? 343 ILE A CD1   1 
ATOM   1530 N N     . ILE A 1 344 ? 147.305 148.778 135.248 1.00 13.86  ? 344 ILE A N     1 
ATOM   1531 C CA    . ILE A 1 344 ? 146.997 148.732 136.675 1.00 14.02  ? 344 ILE A CA    1 
ATOM   1532 C C     . ILE A 1 344 ? 145.595 149.270 136.938 1.00 12.30  ? 344 ILE A C     1 
ATOM   1533 O O     . ILE A 1 344 ? 144.839 148.709 137.743 1.00 16.82  ? 344 ILE A O     1 
ATOM   1534 C CB    . ILE A 1 344 ? 148.069 149.488 137.480 1.00 13.70  ? 344 ILE A CB    1 
ATOM   1535 C CG1   . ILE A 1 344 ? 149.411 148.762 137.360 1.00 15.22  ? 344 ILE A CG1   1 
ATOM   1536 C CG2   . ILE A 1 344 ? 147.660 149.599 138.938 1.00 11.13  ? 344 ILE A CG2   1 
ATOM   1537 C CD1   . ILE A 1 344 ? 150.613 149.614 137.685 1.00 15.72  ? 344 ILE A CD1   1 
ATOM   1538 N N     . LYS A 1 345 ? 145.216 150.354 136.254 1.00 11.10  ? 345 LYS A N     1 
ATOM   1539 C CA    . LYS A 1 345 ? 143.860 150.876 136.400 1.00 12.47  ? 345 LYS A CA    1 
ATOM   1540 C C     . LYS A 1 345 ? 142.822 149.862 135.930 1.00 15.86  ? 345 LYS A C     1 
ATOM   1541 O O     . LYS A 1 345 ? 141.774 149.692 136.565 1.00 18.39  ? 345 LYS A O     1 
ATOM   1542 C CB    . LYS A 1 345 ? 143.722 152.192 135.632 1.00 15.59  ? 345 LYS A CB    1 
ATOM   1543 C CG    . LYS A 1 345 ? 142.325 152.794 135.649 1.00 14.07  ? 345 LYS A CG    1 
ATOM   1544 C CD    . LYS A 1 345 ? 141.613 152.593 134.320 1.00 16.78  ? 345 LYS A CD    1 
ATOM   1545 C CE    . LYS A 1 345 ? 140.444 153.553 134.170 1.00 21.14  ? 345 LYS A CE    1 
ATOM   1546 N NZ    . LYS A 1 345 ? 139.797 153.435 132.833 1.00 18.92  ? 345 LYS A NZ    1 
ATOM   1547 N N     . ASN A 1 346 ? 143.096 149.179 134.817 1.00 13.19  ? 346 ASN A N     1 
ATOM   1548 C CA    . ASN A 1 346 ? 142.174 148.167 134.311 1.00 16.99  ? 346 ASN A CA    1 
ATOM   1549 C C     . ASN A 1 346 ? 142.059 146.991 135.272 1.00 19.64  ? 346 ASN A C     1 
ATOM   1550 O O     . ASN A 1 346 ? 140.971 146.434 135.449 1.00 23.75  ? 346 ASN A O     1 
ATOM   1551 C CB    . ASN A 1 346 ? 142.627 147.689 132.931 1.00 19.07  ? 346 ASN A CB    1 
ATOM   1552 C CG    . ASN A 1 346 ? 142.248 148.654 131.827 1.00 18.92  ? 346 ASN A CG    1 
ATOM   1553 O OD1   . ASN A 1 346 ? 141.559 149.646 132.063 1.00 18.36  ? 346 ASN A OD1   1 
ATOM   1554 N ND2   . ASN A 1 346 ? 142.700 148.368 130.612 1.00 14.46  ? 346 ASN A ND2   1 
ATOM   1555 N N     . ASN A 1 347 ? 143.174 146.587 135.884 1.00 15.34  ? 347 ASN A N     1 
ATOM   1556 C CA    . ASN A 1 347 ? 143.133 145.517 136.875 1.00 14.51  ? 347 ASN A CA    1 
ATOM   1557 C C     . ASN A 1 347 ? 142.316 145.929 138.091 1.00 19.32  ? 347 ASN A C     1 
ATOM   1558 O O     . ASN A 1 347 ? 141.554 145.123 138.638 1.00 22.50  ? 347 ASN A O     1 
ATOM   1559 C CB    . ASN A 1 347 ? 144.551 145.128 137.290 1.00 12.71  ? 347 ASN A CB    1 
ATOM   1560 C CG    . ASN A 1 347 ? 145.300 144.399 136.194 1.00 20.13  ? 347 ASN A CG    1 
ATOM   1561 O OD1   . ASN A 1 347 ? 144.695 143.770 135.326 1.00 23.64  ? 347 ASN A OD1   1 
ATOM   1562 N ND2   . ASN A 1 347 ? 146.625 144.478 136.229 1.00 17.32  ? 347 ASN A ND2   1 
ATOM   1563 N N     . LEU A 1 348 ? 142.468 147.179 138.533 1.00 18.73  ? 348 LEU A N     1 
ATOM   1564 C CA    . LEU A 1 348 ? 141.654 147.671 139.641 1.00 17.07  ? 348 LEU A CA    1 
ATOM   1565 C C     . LEU A 1 348 ? 140.175 147.671 139.278 1.00 20.26  ? 348 LEU A C     1 
ATOM   1566 O O     . LEU A 1 348 ? 139.326 147.300 140.097 1.00 26.00  ? 348 LEU A O     1 
ATOM   1567 C CB    . LEU A 1 348 ? 142.105 149.074 140.043 1.00 18.26  ? 348 LEU A CB    1 
ATOM   1568 C CG    . LEU A 1 348 ? 143.497 149.190 140.661 1.00 19.19  ? 348 LEU A CG    1 
ATOM   1569 C CD1   . LEU A 1 348 ? 143.925 150.646 140.747 1.00 19.26  ? 348 LEU A CD1   1 
ATOM   1570 C CD2   . LEU A 1 348 ? 143.520 148.538 142.030 1.00 20.63  ? 348 LEU A CD2   1 
ATOM   1571 N N     . LYS A 1 349 ? 139.847 148.092 138.054 1.00 21.40  ? 349 LYS A N     1 
ATOM   1572 C CA    . LYS A 1 349 ? 138.452 148.105 137.623 1.00 22.25  ? 349 LYS A CA    1 
ATOM   1573 C C     . LYS A 1 349 ? 137.880 146.694 137.536 1.00 23.33  ? 349 LYS A C     1 
ATOM   1574 O O     . LYS A 1 349 ? 136.730 146.460 137.927 1.00 24.31  ? 349 LYS A O     1 
ATOM   1575 C CB    . LYS A 1 349 ? 138.327 148.819 136.277 1.00 20.79  ? 349 LYS A CB    1 
ATOM   1576 N N     . ASP A 1 350 ? 138.663 145.743 137.021 1.00 22.37  ? 350 ASP A N     1 
ATOM   1577 C CA    . ASP A 1 350 ? 138.173 144.379 136.851 1.00 24.61  ? 350 ASP A CA    1 
ATOM   1578 C C     . ASP A 1 350 ? 137.971 143.676 138.186 1.00 27.50  ? 350 ASP A C     1 
ATOM   1579 O O     . ASP A 1 350 ? 137.042 142.873 138.327 1.00 30.98  ? 350 ASP A O     1 
ATOM   1580 C CB    . ASP A 1 350 ? 139.138 143.580 135.976 1.00 25.59  ? 350 ASP A CB    1 
ATOM   1581 C CG    . ASP A 1 350 ? 139.155 144.059 134.537 1.00 29.04  ? 350 ASP A CG    1 
ATOM   1582 O OD1   . ASP A 1 350 ? 138.282 144.873 134.169 1.00 27.79  ? 350 ASP A OD1   1 
ATOM   1583 O OD2   . ASP A 1 350 ? 140.042 143.621 133.775 1.00 29.92  ? 350 ASP A OD2   1 
ATOM   1584 N N     . CYS A 1 351 ? 138.823 143.957 139.169 1.00 27.44  ? 351 CYS A N     1 
ATOM   1585 C CA    . CYS A 1 351 ? 138.735 143.320 140.477 1.00 23.44  ? 351 CYS A CA    1 
ATOM   1586 C C     . CYS A 1 351 ? 137.629 143.898 141.348 1.00 25.71  ? 351 CYS A C     1 
ATOM   1587 O O     . CYS A 1 351 ? 137.476 143.461 142.494 1.00 32.24  ? 351 CYS A O     1 
ATOM   1588 C CB    . CYS A 1 351 ? 140.074 143.437 141.208 1.00 18.75  ? 351 CYS A CB    1 
ATOM   1589 S SG    . CYS A 1 351 ? 141.382 142.388 140.541 1.00 29.66  ? 351 CYS A SG    1 
ATOM   1590 N N     . GLY A 1 352 ? 136.860 144.856 140.843 1.00 21.32  ? 352 GLY A N     1 
ATOM   1591 C CA    . GLY A 1 352 ? 135.860 145.517 141.662 1.00 21.81  ? 352 GLY A CA    1 
ATOM   1592 C C     . GLY A 1 352 ? 136.461 146.348 142.773 1.00 22.12  ? 352 GLY A C     1 
ATOM   1593 O O     . GLY A 1 352 ? 135.893 146.415 143.870 1.00 26.76  ? 352 GLY A O     1 
ATOM   1594 N N     . LEU A 1 353 ? 137.603 146.981 142.516 1.00 21.56  ? 353 LEU A N     1 
ATOM   1595 C CA    . LEU A 1 353 ? 138.281 147.806 143.503 1.00 22.29  ? 353 LEU A CA    1 
ATOM   1596 C C     . LEU A 1 353 ? 138.361 149.269 143.093 1.00 23.69  ? 353 LEU A C     1 
ATOM   1597 O O     . LEU A 1 353 ? 138.948 150.072 143.827 1.00 23.15  ? 353 LEU A O     1 
ATOM   1598 C CB    . LEU A 1 353 ? 139.693 147.263 143.763 1.00 20.72  ? 353 LEU A CB    1 
ATOM   1599 C CG    . LEU A 1 353 ? 140.266 147.432 145.170 1.00 20.40  ? 353 LEU A CG    1 
ATOM   1600 C CD1   . LEU A 1 353 ? 139.400 146.712 146.189 1.00 23.36  ? 353 LEU A CD1   1 
ATOM   1601 C CD2   . LEU A 1 353 ? 141.693 146.916 145.218 1.00 20.27  ? 353 LEU A CD2   1 
ATOM   1602 N N     . PHE A 1 354 ? 137.789 149.637 141.952 1.00 25.13  ? 354 PHE A N     1 
ATOM   1603 C CA    . PHE A 1 354 ? 137.821 151.015 141.479 1.00 29.66  ? 354 PHE A CA    1 
ATOM   1604 C C     . PHE A 1 354 ? 136.472 151.411 140.888 1.00 32.76  ? 354 PHE A C     1 
ATOM   1605 O O     . PHE A 1 354 ? 135.990 152.524 141.095 1.00 31.73  ? 354 PHE A O     1 
ATOM   1606 C CB    . PHE A 1 354 ? 138.932 151.197 140.441 1.00 27.85  ? 354 PHE A CB    1 
ATOM   1607 C CG    . PHE A 1 354 ? 138.769 152.420 139.586 1.00 26.63  ? 354 PHE A CG    1 
ATOM   1608 C CD1   . PHE A 1 354 ? 138.822 153.686 140.143 1.00 26.82  ? 354 PHE A CD1   1 
ATOM   1609 C CD2   . PHE A 1 354 ? 138.562 152.303 138.222 1.00 25.82  ? 354 PHE A CD2   1 
ATOM   1610 C CE1   . PHE A 1 354 ? 138.671 154.812 139.357 1.00 27.89  ? 354 PHE A CE1   1 
ATOM   1611 C CE2   . PHE A 1 354 ? 138.411 153.424 137.430 1.00 27.33  ? 354 PHE A CE2   1 
ATOM   1612 C CZ    . PHE A 1 354 ? 138.465 154.680 137.998 1.00 29.29  ? 354 PHE A CZ    1 
ATOM   1613 O OXT   . PHE A 1 354 ? 135.830 150.623 140.193 1.00 30.53  ? 354 PHE A OXT   1 
ATOM   1614 N N     . LEU B 2 15  ? 129.200 169.779 82.012  1.00 65.02  ? 4   LEU B N     1 
ATOM   1615 C CA    . LEU B 2 15  ? 129.135 169.757 83.469  1.00 66.67  ? 4   LEU B CA    1 
ATOM   1616 C C     . LEU B 2 15  ? 127.739 170.130 83.959  1.00 67.05  ? 4   LEU B C     1 
ATOM   1617 O O     . LEU B 2 15  ? 127.016 169.291 84.496  1.00 66.47  ? 4   LEU B O     1 
ATOM   1618 C CB    . LEU B 2 15  ? 130.175 170.706 84.067  1.00 65.49  ? 4   LEU B CB    1 
ATOM   1619 N N     . ASP B 2 16  ? 127.371 171.400 83.775  1.00 66.90  ? 5   ASP B N     1 
ATOM   1620 C CA    . ASP B 2 16  ? 126.043 171.850 84.180  1.00 66.49  ? 5   ASP B CA    1 
ATOM   1621 C C     . ASP B 2 16  ? 124.954 171.160 83.366  1.00 66.86  ? 5   ASP B C     1 
ATOM   1622 O O     . ASP B 2 16  ? 123.915 170.770 83.911  1.00 66.36  ? 5   ASP B O     1 
ATOM   1623 C CB    . ASP B 2 16  ? 125.938 173.369 84.040  1.00 65.72  ? 5   ASP B CB    1 
ATOM   1624 N N     . GLN B 2 17  ? 125.173 171.008 82.058  1.00 64.51  ? 6   GLN B N     1 
ATOM   1625 C CA    . GLN B 2 17  ? 124.196 170.318 81.220  1.00 64.11  ? 6   GLN B CA    1 
ATOM   1626 C C     . GLN B 2 17  ? 124.049 168.859 81.631  1.00 64.07  ? 6   GLN B C     1 
ATOM   1627 O O     . GLN B 2 17  ? 122.934 168.326 81.672  1.00 64.01  ? 6   GLN B O     1 
ATOM   1628 C CB    . GLN B 2 17  ? 124.599 170.425 79.749  1.00 62.86  ? 6   GLN B CB    1 
ATOM   1629 N N     . LEU B 2 18  ? 125.166 168.195 81.938  1.00 61.15  ? 7   LEU B N     1 
ATOM   1630 C CA    . LEU B 2 18  ? 125.100 166.807 82.383  1.00 60.43  ? 7   LEU B CA    1 
ATOM   1631 C C     . LEU B 2 18  ? 124.379 166.690 83.720  1.00 61.28  ? 7   LEU B C     1 
ATOM   1632 O O     . LEU B 2 18  ? 123.605 165.750 83.935  1.00 61.61  ? 7   LEU B O     1 
ATOM   1633 C CB    . LEU B 2 18  ? 126.507 166.217 82.473  1.00 60.61  ? 7   LEU B CB    1 
ATOM   1634 C CG    . LEU B 2 18  ? 127.115 165.774 81.140  1.00 61.61  ? 7   LEU B CG    1 
ATOM   1635 C CD1   . LEU B 2 18  ? 128.519 165.224 81.337  1.00 61.11  ? 7   LEU B CD1   1 
ATOM   1636 C CD2   . LEU B 2 18  ? 126.224 164.747 80.460  1.00 61.20  ? 7   LEU B CD2   1 
ATOM   1637 N N     . ARG B 2 19  ? 124.619 167.635 84.633  1.00 60.64  ? 8   ARG B N     1 
ATOM   1638 C CA    . ARG B 2 19  ? 123.912 167.624 85.909  1.00 59.81  ? 8   ARG B CA    1 
ATOM   1639 C C     . ARG B 2 19  ? 122.415 167.832 85.712  1.00 60.36  ? 8   ARG B C     1 
ATOM   1640 O O     . ARG B 2 19  ? 121.596 167.173 86.366  1.00 60.30  ? 8   ARG B O     1 
ATOM   1641 C CB    . ARG B 2 19  ? 124.485 168.695 86.837  1.00 59.83  ? 8   ARG B CB    1 
ATOM   1642 N N     . GLN B 2 20  ? 122.037 168.746 84.814  1.00 60.89  ? 9   GLN B N     1 
ATOM   1643 C CA    . GLN B 2 20  ? 120.622 168.960 84.527  1.00 60.86  ? 9   GLN B CA    1 
ATOM   1644 C C     . GLN B 2 20  ? 119.988 167.715 83.919  1.00 60.50  ? 9   GLN B C     1 
ATOM   1645 O O     . GLN B 2 20  ? 118.855 167.356 84.261  1.00 60.03  ? 9   GLN B O     1 
ATOM   1646 C CB    . GLN B 2 20  ? 120.452 170.160 83.595  1.00 60.38  ? 9   GLN B CB    1 
ATOM   1647 N N     . GLU B 2 21  ? 120.704 167.045 83.013  1.00 59.50  ? 10  GLU B N     1 
ATOM   1648 C CA    . GLU B 2 21  ? 120.184 165.816 82.420  1.00 59.67  ? 10  GLU B CA    1 
ATOM   1649 C C     . GLU B 2 21  ? 120.024 164.722 83.469  1.00 59.30  ? 10  GLU B C     1 
ATOM   1650 O O     . GLU B 2 21  ? 119.041 163.973 83.451  1.00 59.13  ? 10  GLU B O     1 
ATOM   1651 C CB    . GLU B 2 21  ? 121.099 165.348 81.289  1.00 59.51  ? 10  GLU B CB    1 
ATOM   1652 C CG    . GLU B 2 21  ? 120.548 164.176 80.493  1.00 60.08  ? 10  GLU B CG    1 
ATOM   1653 C CD    . GLU B 2 21  ? 121.205 164.034 79.135  1.00 60.75  ? 10  GLU B CD    1 
ATOM   1654 O OE1   . GLU B 2 21  ? 122.080 164.863 78.807  1.00 60.81  ? 10  GLU B OE1   1 
ATOM   1655 O OE2   . GLU B 2 21  ? 120.847 163.093 78.396  1.00 59.51  ? 10  GLU B OE2   1 
ATOM   1656 N N     . ALA B 2 22  ? 120.988 164.608 84.386  1.00 56.65  ? 11  ALA B N     1 
ATOM   1657 C CA    . ALA B 2 22  ? 120.876 163.627 85.461  1.00 56.08  ? 11  ALA B CA    1 
ATOM   1658 C C     . ALA B 2 22  ? 119.688 163.932 86.364  1.00 56.89  ? 11  ALA B C     1 
ATOM   1659 O O     . ALA B 2 22  ? 118.966 163.020 86.783  1.00 57.02  ? 11  ALA B O     1 
ATOM   1660 C CB    . ALA B 2 22  ? 122.171 163.586 86.272  1.00 55.58  ? 11  ALA B CB    1 
ATOM   1661 N N     . GLU B 2 23  ? 119.472 165.212 86.678  1.00 55.14  ? 12  GLU B N     1 
ATOM   1662 C CA    . GLU B 2 23  ? 118.315 165.588 87.485  1.00 54.65  ? 12  GLU B CA    1 
ATOM   1663 C C     . GLU B 2 23  ? 117.012 165.261 86.765  1.00 54.57  ? 12  GLU B C     1 
ATOM   1664 O O     . GLU B 2 23  ? 116.056 164.778 87.383  1.00 54.44  ? 12  GLU B O     1 
ATOM   1665 C CB    . GLU B 2 23  ? 118.379 167.075 87.834  1.00 53.99  ? 12  GLU B CB    1 
ATOM   1666 N N     . GLN B 2 24  ? 116.956 165.520 85.457  1.00 54.26  ? 13  GLN B N     1 
ATOM   1667 C CA    . GLN B 2 24  ? 115.762 165.190 84.685  1.00 54.42  ? 13  GLN B CA    1 
ATOM   1668 C C     . GLN B 2 24  ? 115.514 163.687 84.665  1.00 54.84  ? 13  GLN B C     1 
ATOM   1669 O O     . GLN B 2 24  ? 114.368 163.237 84.779  1.00 55.52  ? 13  GLN B O     1 
ATOM   1670 C CB    . GLN B 2 24  ? 115.890 165.733 83.262  1.00 53.26  ? 13  GLN B CB    1 
ATOM   1671 N N     . LEU B 2 25  ? 116.577 162.893 84.514  1.00 52.22  ? 14  LEU B N     1 
ATOM   1672 C CA    . LEU B 2 25  ? 116.427 161.441 84.527  1.00 51.31  ? 14  LEU B CA    1 
ATOM   1673 C C     . LEU B 2 25  ? 115.955 160.944 85.889  1.00 50.93  ? 14  LEU B C     1 
ATOM   1674 O O     . LEU B 2 25  ? 115.113 160.042 85.969  1.00 51.62  ? 14  LEU B O     1 
ATOM   1675 C CB    . LEU B 2 25  ? 117.745 160.775 84.136  1.00 51.35  ? 14  LEU B CB    1 
ATOM   1676 C CG    . LEU B 2 25  ? 118.084 160.807 82.645  1.00 51.74  ? 14  LEU B CG    1 
ATOM   1677 C CD1   . LEU B 2 25  ? 119.540 160.440 82.416  1.00 51.75  ? 14  LEU B CD1   1 
ATOM   1678 C CD2   . LEU B 2 25  ? 117.164 159.879 81.869  1.00 50.81  ? 14  LEU B CD2   1 
ATOM   1679 N N     . LYS B 2 26  ? 116.490 161.516 86.970  1.00 49.19  ? 15  LYS B N     1 
ATOM   1680 C CA    . LYS B 2 26  ? 116.033 161.144 88.305  1.00 48.74  ? 15  LYS B CA    1 
ATOM   1681 C C     . LYS B 2 26  ? 114.567 161.506 88.505  1.00 47.69  ? 15  LYS B C     1 
ATOM   1682 O O     . LYS B 2 26  ? 113.803 160.736 89.101  1.00 48.22  ? 15  LYS B O     1 
ATOM   1683 C CB    . LYS B 2 26  ? 116.904 161.818 89.365  1.00 47.87  ? 15  LYS B CB    1 
ATOM   1684 N N     . ASN B 2 27  ? 114.156 162.678 88.016  1.00 47.27  ? 16  ASN B N     1 
ATOM   1685 C CA    . ASN B 2 27  ? 112.754 163.071 88.108  1.00 48.22  ? 16  ASN B CA    1 
ATOM   1686 C C     . ASN B 2 27  ? 111.864 162.124 87.314  1.00 47.73  ? 16  ASN B C     1 
ATOM   1687 O O     . ASN B 2 27  ? 110.770 161.765 87.764  1.00 47.70  ? 16  ASN B O     1 
ATOM   1688 C CB    . ASN B 2 27  ? 112.580 164.509 87.621  1.00 49.03  ? 16  ASN B CB    1 
ATOM   1689 C CG    . ASN B 2 27  ? 113.184 165.523 88.572  1.00 49.86  ? 16  ASN B CG    1 
ATOM   1690 O OD1   . ASN B 2 27  ? 113.440 165.222 89.737  1.00 49.75  ? 16  ASN B OD1   1 
ATOM   1691 N ND2   . ASN B 2 27  ? 113.415 166.734 88.077  1.00 48.46  ? 16  ASN B ND2   1 
ATOM   1692 N N     . GLN B 2 28  ? 112.313 161.713 86.126  1.00 46.95  ? 17  GLN B N     1 
ATOM   1693 C CA    . GLN B 2 28  ? 111.549 160.756 85.331  1.00 47.13  ? 17  GLN B CA    1 
ATOM   1694 C C     . GLN B 2 28  ? 111.425 159.417 86.047  1.00 46.72  ? 17  GLN B C     1 
ATOM   1695 O O     . GLN B 2 28  ? 110.357 158.792 86.036  1.00 45.73  ? 17  GLN B O     1 
ATOM   1696 C CB    . GLN B 2 28  ? 112.205 160.575 83.962  1.00 46.07  ? 17  GLN B CB    1 
ATOM   1697 C CG    . GLN B 2 28  ? 111.573 159.492 83.104  1.00 45.88  ? 17  GLN B CG    1 
ATOM   1698 C CD    . GLN B 2 28  ? 112.096 159.499 81.682  1.00 47.41  ? 17  GLN B CD    1 
ATOM   1699 O OE1   . GLN B 2 28  ? 112.836 160.399 81.284  1.00 48.25  ? 17  GLN B OE1   1 
ATOM   1700 N NE2   . GLN B 2 28  ? 111.714 158.491 80.906  1.00 46.91  ? 17  GLN B NE2   1 
ATOM   1701 N N     . ILE B 2 29  ? 112.512 158.959 86.672  1.00 42.64  ? 18  ILE B N     1 
ATOM   1702 C CA    . ILE B 2 29  ? 112.476 157.703 87.417  1.00 40.55  ? 18  ILE B CA    1 
ATOM   1703 C C     . ILE B 2 29  ? 111.496 157.802 88.579  1.00 40.74  ? 18  ILE B C     1 
ATOM   1704 O O     . ILE B 2 29  ? 110.699 156.886 88.823  1.00 40.76  ? 18  ILE B O     1 
ATOM   1705 C CB    . ILE B 2 29  ? 113.891 157.330 87.896  1.00 39.35  ? 18  ILE B CB    1 
ATOM   1706 C CG1   . ILE B 2 29  ? 114.729 156.805 86.731  1.00 38.58  ? 18  ILE B CG1   1 
ATOM   1707 C CG2   . ILE B 2 29  ? 113.829 156.298 89.007  1.00 40.38  ? 18  ILE B CG2   1 
ATOM   1708 C CD1   . ILE B 2 29  ? 116.218 156.847 86.982  1.00 39.27  ? 18  ILE B CD1   1 
ATOM   1709 N N     . ARG B 2 30  ? 111.539 158.917 89.314  1.00 39.97  ? 19  ARG B N     1 
ATOM   1710 C CA    . ARG B 2 30  ? 110.618 159.107 90.429  1.00 39.33  ? 19  ARG B CA    1 
ATOM   1711 C C     . ARG B 2 30  ? 109.172 159.159 89.950  1.00 40.17  ? 19  ARG B C     1 
ATOM   1712 O O     . ARG B 2 30  ? 108.275 158.610 90.599  1.00 38.76  ? 19  ARG B O     1 
ATOM   1713 C CB    . ARG B 2 30  ? 110.976 160.381 91.194  1.00 38.09  ? 19  ARG B CB    1 
ATOM   1714 N N     . ASP B 2 31  ? 108.927 159.822 88.817  1.00 42.91  ? 20  ASP B N     1 
ATOM   1715 C CA    . ASP B 2 31  ? 107.575 159.889 88.273  1.00 41.31  ? 20  ASP B CA    1 
ATOM   1716 C C     . ASP B 2 31  ? 107.075 158.511 87.860  1.00 42.11  ? 20  ASP B C     1 
ATOM   1717 O O     . ASP B 2 31  ? 105.911 158.171 88.100  1.00 43.37  ? 20  ASP B O     1 
ATOM   1718 C CB    . ASP B 2 31  ? 107.534 160.853 87.088  1.00 42.20  ? 20  ASP B CB    1 
ATOM   1719 C CG    . ASP B 2 31  ? 107.703 162.300 87.508  1.00 43.89  ? 20  ASP B CG    1 
ATOM   1720 O OD1   . ASP B 2 31  ? 107.559 162.591 88.714  1.00 41.89  ? 20  ASP B OD1   1 
ATOM   1721 O OD2   . ASP B 2 31  ? 107.981 163.146 86.632  1.00 44.04  ? 20  ASP B OD2   1 
ATOM   1722 N N     . ALA B 2 32  ? 107.937 157.707 87.233  1.00 38.89  ? 21  ALA B N     1 
ATOM   1723 C CA    . ALA B 2 32  ? 107.546 156.348 86.869  1.00 38.04  ? 21  ALA B CA    1 
ATOM   1724 C C     . ALA B 2 32  ? 107.243 155.512 88.107  1.00 36.86  ? 21  ALA B C     1 
ATOM   1725 O O     . ALA B 2 32  ? 106.263 154.756 88.132  1.00 36.66  ? 21  ALA B O     1 
ATOM   1726 C CB    . ALA B 2 32  ? 108.643 155.691 86.032  1.00 37.86  ? 21  ALA B CB    1 
ATOM   1727 N N     . ARG B 2 33  ? 108.072 155.639 89.146  1.00 31.79  ? 22  ARG B N     1 
ATOM   1728 C CA    . ARG B 2 33  ? 107.825 154.912 90.387  1.00 30.91  ? 22  ARG B CA    1 
ATOM   1729 C C     . ARG B 2 33  ? 106.494 155.323 91.006  1.00 30.28  ? 22  ARG B C     1 
ATOM   1730 O O     . ARG B 2 33  ? 105.713 154.473 91.449  1.00 29.79  ? 22  ARG B O     1 
ATOM   1731 C CB    . ARG B 2 33  ? 108.971 155.150 91.370  1.00 29.04  ? 22  ARG B CB    1 
ATOM   1732 C CG    . ARG B 2 33  ? 110.255 154.416 91.030  1.00 25.65  ? 22  ARG B CG    1 
ATOM   1733 C CD    . ARG B 2 33  ? 111.272 154.563 92.150  1.00 28.45  ? 22  ARG B CD    1 
ATOM   1734 N NE    . ARG B 2 33  ? 112.632 154.701 91.645  1.00 31.30  ? 22  ARG B NE    1 
ATOM   1735 C CZ    . ARG B 2 33  ? 113.625 153.871 91.929  1.00 29.97  ? 22  ARG B CZ    1 
ATOM   1736 N NH1   . ARG B 2 33  ? 113.448 152.826 92.720  1.00 29.65  ? 22  ARG B NH1   1 
ATOM   1737 N NH2   . ARG B 2 33  ? 114.828 154.095 91.408  1.00 27.51  ? 22  ARG B NH2   1 
ATOM   1738 N N     . LYS B 2 34  ? 106.216 156.628 91.039  1.00 33.25  ? 23  LYS B N     1 
ATOM   1739 C CA    . LYS B 2 34  ? 104.952 157.105 91.590  1.00 32.73  ? 23  LYS B CA    1 
ATOM   1740 C C     . LYS B 2 34  ? 103.765 156.622 90.770  1.00 32.79  ? 23  LYS B C     1 
ATOM   1741 O O     . LYS B 2 34  ? 102.721 156.280 91.337  1.00 32.53  ? 23  LYS B O     1 
ATOM   1742 C CB    . LYS B 2 34  ? 104.956 158.632 91.670  1.00 31.63  ? 23  LYS B CB    1 
ATOM   1743 N N     . ALA B 2 35  ? 103.901 156.593 89.442  1.00 32.53  ? 24  ALA B N     1 
ATOM   1744 C CA    . ALA B 2 35  ? 102.828 156.080 88.597  1.00 33.85  ? 24  ALA B CA    1 
ATOM   1745 C C     . ALA B 2 35  ? 102.575 154.602 88.852  1.00 34.86  ? 24  ALA B C     1 
ATOM   1746 O O     . ALA B 2 35  ? 101.419 154.165 88.870  1.00 35.30  ? 24  ALA B O     1 
ATOM   1747 C CB    . ALA B 2 35  ? 103.160 156.317 87.124  1.00 33.69  ? 24  ALA B CB    1 
ATOM   1748 N N     . CYS B 2 36  ? 103.635 153.818 89.052  1.00 34.58  ? 25  CYS B N     1 
ATOM   1749 C CA    . CYS B 2 36  ? 103.472 152.397 89.330  1.00 32.84  ? 25  CYS B CA    1 
ATOM   1750 C C     . CYS B 2 36  ? 102.968 152.115 90.740  1.00 33.65  ? 25  CYS B C     1 
ATOM   1751 O O     . CYS B 2 36  ? 102.577 150.978 91.022  1.00 33.42  ? 25  CYS B O     1 
ATOM   1752 C CB    . CYS B 2 36  ? 104.795 151.662 89.103  1.00 32.31  ? 25  CYS B CB    1 
ATOM   1753 S SG    . CYS B 2 36  ? 105.378 151.707 87.395  1.00 39.38  ? 25  CYS B SG    1 
ATOM   1754 N N     . ALA B 2 37  ? 102.964 153.111 91.625  1.00 32.55  ? 26  ALA B N     1 
ATOM   1755 C CA    . ALA B 2 37  ? 102.516 152.922 93.006  1.00 30.18  ? 26  ALA B CA    1 
ATOM   1756 C C     . ALA B 2 37  ? 101.014 153.186 93.129  1.00 32.59  ? 26  ALA B C     1 
ATOM   1757 O O     . ALA B 2 37  ? 100.565 154.163 93.727  1.00 33.01  ? 26  ALA B O     1 
ATOM   1758 C CB    . ALA B 2 37  ? 103.316 153.817 93.946  1.00 29.11  ? 26  ALA B CB    1 
ATOM   1759 N N     . ASP B 2 38  ? 100.232 152.280 92.538  1.00 32.37  ? 27  ASP B N     1 
ATOM   1760 C CA    . ASP B 2 38  ? 98.779  152.409 92.603  1.00 33.95  ? 27  ASP B CA    1 
ATOM   1761 C C     . ASP B 2 38  ? 98.260  152.141 94.011  1.00 35.15  ? 27  ASP B C     1 
ATOM   1762 O O     . ASP B 2 38  ? 97.337  152.818 94.478  1.00 34.67  ? 27  ASP B O     1 
ATOM   1763 C CB    . ASP B 2 38  ? 98.121  151.463 91.599  1.00 32.98  ? 27  ASP B CB    1 
ATOM   1764 C CG    . ASP B 2 38  ? 98.542  150.020 91.793  1.00 33.60  ? 27  ASP B CG    1 
ATOM   1765 O OD1   . ASP B 2 38  ? 99.542  149.780 92.501  1.00 35.59  ? 27  ASP B OD1   1 
ATOM   1766 O OD2   . ASP B 2 38  ? 97.873  149.125 91.237  1.00 33.08  ? 27  ASP B OD2   1 
ATOM   1767 N N     . ALA B 2 39  ? 98.839  151.161 94.700  1.00 34.22  ? 28  ALA B N     1 
ATOM   1768 C CA    . ALA B 2 39  ? 98.419  150.799 96.046  1.00 32.16  ? 28  ALA B CA    1 
ATOM   1769 C C     . ALA B 2 39  ? 99.666  150.570 96.891  1.00 31.77  ? 28  ALA B C     1 
ATOM   1770 O O     . ALA B 2 39  ? 100.793 150.833 96.458  1.00 32.73  ? 28  ALA B O     1 
ATOM   1771 C CB    . ALA B 2 39  ? 97.502  149.569 96.017  1.00 31.04  ? 28  ALA B CB    1 
ATOM   1772 N N     . THR B 2 40  ? 99.462  150.082 98.112  1.00 30.42  ? 29  THR B N     1 
ATOM   1773 C CA    . THR B 2 40  ? 100.549 149.776 99.029  1.00 29.81  ? 29  THR B CA    1 
ATOM   1774 C C     . THR B 2 40  ? 100.363 148.372 99.581  1.00 30.92  ? 29  THR B C     1 
ATOM   1775 O O     . THR B 2 40  ? 99.241  147.868 99.677  1.00 32.23  ? 29  THR B O     1 
ATOM   1776 C CB    . THR B 2 40  ? 100.620 150.782 100.189 1.00 30.55  ? 29  THR B CB    1 
ATOM   1777 O OG1   . THR B 2 40  ? 99.384  150.771 100.912 1.00 30.63  ? 29  THR B OG1   1 
ATOM   1778 C CG2   . THR B 2 40  ? 100.886 152.187 99.670  1.00 30.11  ? 29  THR B CG2   1 
ATOM   1779 N N     . LEU B 2 41  ? 101.483 147.739 99.939  1.00 25.81  ? 30  LEU B N     1 
ATOM   1780 C CA    . LEU B 2 41  ? 101.421 146.407 100.532 1.00 24.43  ? 30  LEU B CA    1 
ATOM   1781 C C     . LEU B 2 41  ? 100.676 146.427 101.861 1.00 26.20  ? 30  LEU B C     1 
ATOM   1782 O O     . LEU B 2 41  ? 99.967  145.467 102.192 1.00 29.17  ? 30  LEU B O     1 
ATOM   1783 C CB    . LEU B 2 41  ? 102.838 145.854 100.709 1.00 23.48  ? 30  LEU B CB    1 
ATOM   1784 C CG    . LEU B 2 41  ? 103.037 144.510 101.413 1.00 24.49  ? 30  LEU B CG    1 
ATOM   1785 C CD1   . LEU B 2 41  ? 102.331 143.402 100.662 1.00 27.45  ? 30  LEU B CD1   1 
ATOM   1786 C CD2   . LEU B 2 41  ? 104.516 144.194 101.540 1.00 23.07  ? 30  LEU B CD2   1 
ATOM   1787 N N     . SER B 2 42  ? 100.817 147.512 102.628 1.00 29.78  ? 31  SER B N     1 
ATOM   1788 C CA    . SER B 2 42  ? 100.111 147.625 103.900 1.00 29.74  ? 31  SER B CA    1 
ATOM   1789 C C     . SER B 2 42  ? 98.601  147.637 103.699 1.00 30.00  ? 31  SER B C     1 
ATOM   1790 O O     . SER B 2 42  ? 97.866  146.966 104.432 1.00 29.34  ? 31  SER B O     1 
ATOM   1791 C CB    . SER B 2 42  ? 100.559 148.887 104.637 1.00 28.65  ? 31  SER B CB    1 
ATOM   1792 N N     . GLN B 2 43  ? 98.119  148.390 102.709 1.00 32.32  ? 32  GLN B N     1 
ATOM   1793 C CA    . GLN B 2 43  ? 96.688  148.449 102.445 1.00 32.72  ? 32  GLN B CA    1 
ATOM   1794 C C     . GLN B 2 43  ? 96.168  147.206 101.738 1.00 32.21  ? 32  GLN B C     1 
ATOM   1795 O O     . GLN B 2 43  ? 94.948  147.033 101.641 1.00 34.17  ? 32  GLN B O     1 
ATOM   1796 C CB    . GLN B 2 43  ? 96.348  149.695 101.621 1.00 32.32  ? 32  GLN B CB    1 
ATOM   1797 C CG    . GLN B 2 43  ? 96.448  149.508 100.117 1.00 32.29  ? 32  GLN B CG    1 
ATOM   1798 C CD    . GLN B 2 43  ? 96.509  150.828 99.374  1.00 33.91  ? 32  GLN B CD    1 
ATOM   1799 O OE1   . GLN B 2 43  ? 97.348  151.679 99.664  1.00 33.65  ? 32  GLN B OE1   1 
ATOM   1800 N NE2   . GLN B 2 43  ? 95.613  151.005 98.409  1.00 33.95  ? 32  GLN B NE2   1 
ATOM   1801 N N     . ILE B 2 44  ? 97.054  146.344 101.249 1.00 30.18  ? 33  ILE B N     1 
ATOM   1802 C CA    . ILE B 2 44  ? 96.638  145.095 100.621 1.00 30.41  ? 33  ILE B CA    1 
ATOM   1803 C C     . ILE B 2 44  ? 96.576  143.959 101.635 1.00 30.36  ? 33  ILE B C     1 
ATOM   1804 O O     . ILE B 2 44  ? 95.677  143.116 101.576 1.00 30.91  ? 33  ILE B O     1 
ATOM   1805 C CB    . ILE B 2 44  ? 97.583  144.764 99.447  1.00 30.18  ? 33  ILE B CB    1 
ATOM   1806 C CG1   . ILE B 2 44  ? 97.275  145.669 98.253  1.00 29.97  ? 33  ILE B CG1   1 
ATOM   1807 C CG2   . ILE B 2 44  ? 97.469  143.302 99.045  1.00 30.43  ? 33  ILE B CG2   1 
ATOM   1808 C CD1   . ILE B 2 44  ? 98.394  145.751 97.244  1.00 30.42  ? 33  ILE B CD1   1 
ATOM   1809 N N     . THR B 2 45  ? 97.505  143.926 102.590 1.00 30.51  ? 34  THR B N     1 
ATOM   1810 C CA    . THR B 2 45  ? 97.575  142.844 103.563 1.00 30.39  ? 34  THR B CA    1 
ATOM   1811 C C     . THR B 2 45  ? 96.721  143.090 104.804 1.00 29.92  ? 34  THR B C     1 
ATOM   1812 O O     . THR B 2 45  ? 96.981  142.484 105.850 1.00 30.86  ? 34  THR B O     1 
ATOM   1813 C CB    . THR B 2 45  ? 99.027  142.595 103.976 1.00 29.66  ? 34  THR B CB    1 
ATOM   1814 O OG1   . THR B 2 45  ? 99.608  143.813 104.459 1.00 29.54  ? 34  THR B OG1   1 
ATOM   1815 C CG2   . THR B 2 45  ? 99.832  142.080 102.799 1.00 28.57  ? 34  THR B CG2   1 
ATOM   1816 N N     . ASN B 2 46  ? 95.712  143.961 104.721 1.00 33.07  ? 35  ASN B N     1 
ATOM   1817 C CA    . ASN B 2 46  ? 94.799  144.123 105.848 1.00 33.87  ? 35  ASN B CA    1 
ATOM   1818 C C     . ASN B 2 46  ? 93.793  142.985 105.950 1.00 36.47  ? 35  ASN B C     1 
ATOM   1819 O O     . ASN B 2 46  ? 93.193  142.801 107.014 1.00 36.32  ? 35  ASN B O     1 
ATOM   1820 C CB    . ASN B 2 46  ? 94.049  145.453 105.756 1.00 34.21  ? 35  ASN B CB    1 
ATOM   1821 C CG    . ASN B 2 46  ? 94.964  146.650 105.881 1.00 36.00  ? 35  ASN B CG    1 
ATOM   1822 O OD1   . ASN B 2 46  ? 95.126  147.421 104.939 1.00 36.51  ? 35  ASN B OD1   1 
ATOM   1823 N ND2   . ASN B 2 46  ? 95.573  146.811 107.050 1.00 34.78  ? 35  ASN B ND2   1 
ATOM   1824 N N     . ASN B 2 47  ? 93.593  142.223 104.878 1.00 38.64  ? 36  ASN B N     1 
ATOM   1825 C CA    . ASN B 2 47  ? 92.604  141.155 104.861 1.00 37.48  ? 36  ASN B CA    1 
ATOM   1826 C C     . ASN B 2 47  ? 93.158  139.817 105.331 1.00 36.22  ? 36  ASN B C     1 
ATOM   1827 O O     . ASN B 2 47  ? 92.401  138.843 105.405 1.00 37.75  ? 36  ASN B O     1 
ATOM   1828 C CB    . ASN B 2 47  ? 92.020  141.002 103.452 1.00 36.59  ? 36  ASN B CB    1 
ATOM   1829 N N     . ILE B 2 48  ? 94.446  139.740 105.651 1.00 31.66  ? 37  ILE B N     1 
ATOM   1830 C CA    . ILE B 2 48  ? 95.062  138.501 106.108 1.00 32.72  ? 37  ILE B CA    1 
ATOM   1831 C C     . ILE B 2 48  ? 95.271  138.576 107.613 1.00 32.63  ? 37  ILE B C     1 
ATOM   1832 O O     . ILE B 2 48  ? 95.501  139.649 108.182 1.00 30.76  ? 37  ILE B O     1 
ATOM   1833 C CB    . ILE B 2 48  ? 96.387  138.217 105.369 1.00 32.62  ? 37  ILE B CB    1 
ATOM   1834 C CG1   . ILE B 2 48  ? 97.448  139.257 105.734 1.00 31.62  ? 37  ILE B CG1   1 
ATOM   1835 C CG2   . ILE B 2 48  ? 96.160  138.185 103.868 1.00 31.79  ? 37  ILE B CG2   1 
ATOM   1836 C CD1   . ILE B 2 48  ? 98.779  139.031 105.055 1.00 29.98  ? 37  ILE B CD1   1 
ATOM   1837 N N     . ASP B 2 49  ? 95.176  137.421 108.265 1.00 31.12  ? 38  ASP B N     1 
ATOM   1838 C CA    . ASP B 2 49  ? 95.310  137.369 109.710 1.00 31.51  ? 38  ASP B CA    1 
ATOM   1839 C C     . ASP B 2 49  ? 96.759  137.618 110.126 1.00 31.63  ? 38  ASP B C     1 
ATOM   1840 O O     . ASP B 2 49  ? 97.693  137.230 109.419 1.00 30.59  ? 38  ASP B O     1 
ATOM   1841 C CB    . ASP B 2 49  ? 94.844  136.016 110.240 1.00 29.51  ? 38  ASP B CB    1 
ATOM   1842 N N     . PRO B 2 50  ? 96.971  138.267 111.267 1.00 30.08  ? 39  PRO B N     1 
ATOM   1843 C CA    . PRO B 2 50  ? 98.336  138.457 111.766 1.00 27.77  ? 39  PRO B CA    1 
ATOM   1844 C C     . PRO B 2 50  ? 98.952  137.139 112.209 1.00 28.29  ? 39  PRO B C     1 
ATOM   1845 O O     . PRO B 2 50  ? 98.263  136.170 112.536 1.00 29.22  ? 39  PRO B O     1 
ATOM   1846 C CB    . PRO B 2 50  ? 98.159  139.412 112.954 1.00 27.57  ? 39  PRO B CB    1 
ATOM   1847 C CG    . PRO B 2 50  ? 96.785  139.994 112.796 1.00 28.56  ? 39  PRO B CG    1 
ATOM   1848 C CD    . PRO B 2 50  ? 95.975  138.943 112.113 1.00 27.33  ? 39  PRO B CD    1 
ATOM   1849 N N     . VAL B 2 51  ? 100.287 137.115 112.212 1.00 24.14  ? 40  VAL B N     1 
ATOM   1850 C CA    . VAL B 2 51  ? 101.020 135.916 112.604 1.00 23.48  ? 40  VAL B CA    1 
ATOM   1851 C C     . VAL B 2 51  ? 100.990 135.668 114.103 1.00 24.32  ? 40  VAL B C     1 
ATOM   1852 O O     . VAL B 2 51  ? 101.424 134.601 114.552 1.00 22.72  ? 40  VAL B O     1 
ATOM   1853 C CB    . VAL B 2 51  ? 102.485 135.998 112.131 1.00 22.05  ? 40  VAL B CB    1 
ATOM   1854 C CG1   . VAL B 2 51  ? 102.543 136.132 110.623 1.00 22.14  ? 40  VAL B CG1   1 
ATOM   1855 C CG2   . VAL B 2 51  ? 103.190 137.164 112.798 1.00 21.43  ? 40  VAL B CG2   1 
ATOM   1856 N N     . GLY B 2 52  ? 100.491 136.617 114.887 1.00 27.10  ? 41  GLY B N     1 
ATOM   1857 C CA    . GLY B 2 52  ? 100.459 136.462 116.323 1.00 26.65  ? 41  GLY B CA    1 
ATOM   1858 C C     . GLY B 2 52  ? 101.795 136.781 116.968 1.00 26.67  ? 41  GLY B C     1 
ATOM   1859 O O     . GLY B 2 52  ? 102.709 137.342 116.356 1.00 26.99  ? 41  GLY B O     1 
ATOM   1860 N N     . ARG B 2 53  ? 101.899 136.411 118.241 1.00 24.42  ? 42  ARG B N     1 
ATOM   1861 C CA    . ARG B 2 53  ? 103.105 136.649 119.025 1.00 23.51  ? 42  ARG B CA    1 
ATOM   1862 C C     . ARG B 2 53  ? 104.071 135.492 118.798 1.00 23.55  ? 42  ARG B C     1 
ATOM   1863 O O     . ARG B 2 53  ? 103.821 134.367 119.242 1.00 22.37  ? 42  ARG B O     1 
ATOM   1864 C CB    . ARG B 2 53  ? 102.766 136.800 120.506 1.00 22.46  ? 42  ARG B CB    1 
ATOM   1865 N N     . ILE B 2 54  ? 105.171 135.768 118.105 1.00 21.45  ? 43  ILE B N     1 
ATOM   1866 C CA    . ILE B 2 54  ? 106.180 134.752 117.829 1.00 20.01  ? 43  ILE B CA    1 
ATOM   1867 C C     . ILE B 2 54  ? 107.081 134.618 119.049 1.00 21.40  ? 43  ILE B C     1 
ATOM   1868 O O     . ILE B 2 54  ? 107.694 135.595 119.492 1.00 24.17  ? 43  ILE B O     1 
ATOM   1869 C CB    . ILE B 2 54  ? 106.993 135.105 116.576 1.00 19.38  ? 43  ILE B CB    1 
ATOM   1870 C CG1   . ILE B 2 54  ? 106.075 135.218 115.358 1.00 20.17  ? 43  ILE B CG1   1 
ATOM   1871 C CG2   . ILE B 2 54  ? 108.074 134.066 116.335 1.00 19.17  ? 43  ILE B CG2   1 
ATOM   1872 C CD1   . ILE B 2 54  ? 105.332 133.944 115.029 1.00 20.01  ? 43  ILE B CD1   1 
ATOM   1873 N N     . GLN B 2 55  ? 107.164 133.407 119.594 1.00 18.92  ? 44  GLN B N     1 
ATOM   1874 C CA    . GLN B 2 55  ? 107.955 133.122 120.789 1.00 18.28  ? 44  GLN B CA    1 
ATOM   1875 C C     . GLN B 2 55  ? 109.029 132.106 120.413 1.00 18.56  ? 44  GLN B C     1 
ATOM   1876 O O     . GLN B 2 55  ? 108.823 130.896 120.526 1.00 19.04  ? 44  GLN B O     1 
ATOM   1877 C CB    . GLN B 2 55  ? 107.070 132.608 121.926 1.00 19.43  ? 44  GLN B CB    1 
ATOM   1878 C CG    . GLN B 2 55  ? 105.752 133.349 122.076 1.00 20.56  ? 44  GLN B CG    1 
ATOM   1879 C CD    . GLN B 2 55  ? 105.841 134.505 123.052 1.00 22.67  ? 44  GLN B CD    1 
ATOM   1880 O OE1   . GLN B 2 55  ? 106.883 134.735 123.665 1.00 22.63  ? 44  GLN B OE1   1 
ATOM   1881 N NE2   . GLN B 2 55  ? 104.746 135.240 123.201 1.00 20.76  ? 44  GLN B NE2   1 
ATOM   1882 N N     . MET B 2 56  ? 110.178 132.604 119.964 1.00 15.48  ? 45  MET B N     1 
ATOM   1883 C CA    . MET B 2 56  ? 111.319 131.757 119.638 1.00 13.83  ? 45  MET B CA    1 
ATOM   1884 C C     . MET B 2 56  ? 112.199 131.641 120.877 1.00 13.70  ? 45  MET B C     1 
ATOM   1885 O O     . MET B 2 56  ? 112.842 132.614 121.284 1.00 15.60  ? 45  MET B O     1 
ATOM   1886 C CB    . MET B 2 56  ? 112.106 132.325 118.460 1.00 12.43  ? 45  MET B CB    1 
ATOM   1887 C CG    . MET B 2 56  ? 111.318 132.437 117.168 1.00 13.11  ? 45  MET B CG    1 
ATOM   1888 S SD    . MET B 2 56  ? 112.394 132.717 115.748 1.00 23.30  ? 45  MET B SD    1 
ATOM   1889 C CE    . MET B 2 56  ? 111.239 133.416 114.573 1.00 12.67  ? 45  MET B CE    1 
ATOM   1890 N N     . ARG B 2 57  ? 112.226 130.456 121.475 1.00 10.63  ? 46  ARG B N     1 
ATOM   1891 C CA    . ARG B 2 57  ? 113.057 130.205 122.640 1.00 9.77   ? 46  ARG B CA    1 
ATOM   1892 C C     . ARG B 2 57  ? 114.457 129.796 122.206 1.00 8.76   ? 46  ARG B C     1 
ATOM   1893 O O     . ARG B 2 57  ? 114.647 129.159 121.165 1.00 12.17  ? 46  ARG B O     1 
ATOM   1894 C CB    . ARG B 2 57  ? 112.442 129.118 123.522 1.00 9.23   ? 46  ARG B CB    1 
ATOM   1895 N N     . THR B 2 58  ? 115.443 130.181 123.012 1.00 5.85   ? 47  THR B N     1 
ATOM   1896 C CA    . THR B 2 58  ? 116.825 129.819 122.737 1.00 4.68   ? 47  THR B CA    1 
ATOM   1897 C C     . THR B 2 58  ? 117.063 128.361 123.113 1.00 8.10   ? 47  THR B C     1 
ATOM   1898 O O     . THR B 2 58  ? 116.663 127.908 124.190 1.00 10.19  ? 47  THR B O     1 
ATOM   1899 C CB    . THR B 2 58  ? 117.786 130.744 123.489 1.00 6.96   ? 47  THR B CB    1 
ATOM   1900 O OG1   . THR B 2 58  ? 119.136 130.315 123.275 1.00 10.08  ? 47  THR B OG1   1 
ATOM   1901 C CG2   . THR B 2 58  ? 117.481 130.769 124.982 1.00 10.14  ? 47  THR B CG2   1 
ATOM   1902 N N     . ARG B 2 59  ? 117.696 127.623 122.206 1.00 6.00   ? 48  ARG B N     1 
ATOM   1903 C CA    . ARG B 2 59  ? 117.954 126.199 122.370 1.00 6.61   ? 48  ARG B CA    1 
ATOM   1904 C C     . ARG B 2 59  ? 119.430 125.867 122.503 1.00 9.83   ? 48  ARG B C     1 
ATOM   1905 O O     . ARG B 2 59  ? 119.795 125.015 123.315 1.00 14.57  ? 48  ARG B O     1 
ATOM   1906 C CB    . ARG B 2 59  ? 117.365 125.424 121.187 1.00 6.11   ? 48  ARG B CB    1 
ATOM   1907 C CG    . ARG B 2 59  ? 115.924 125.791 120.878 1.00 6.77   ? 48  ARG B CG    1 
ATOM   1908 C CD    . ARG B 2 59  ? 115.002 125.363 122.009 1.00 8.16   ? 48  ARG B CD    1 
ATOM   1909 N NE    . ARG B 2 59  ? 113.655 125.899 121.859 1.00 9.69   ? 48  ARG B NE    1 
ATOM   1910 C CZ    . ARG B 2 59  ? 112.722 125.373 121.078 1.00 11.58  ? 48  ARG B CZ    1 
ATOM   1911 N NH1   . ARG B 2 59  ? 112.956 124.293 120.352 1.00 11.90  ? 48  ARG B NH1   1 
ATOM   1912 N NH2   . ARG B 2 59  ? 111.523 125.946 121.024 1.00 7.83   ? 48  ARG B NH2   1 
ATOM   1913 N N     . ARG B 2 60  ? 120.290 126.519 121.726 1.00 5.76   ? 49  ARG B N     1 
ATOM   1914 C CA    . ARG B 2 60  ? 121.727 126.305 121.785 1.00 3.60   ? 49  ARG B CA    1 
ATOM   1915 C C     . ARG B 2 60  ? 122.435 127.630 122.025 1.00 6.24   ? 49  ARG B C     1 
ATOM   1916 O O     . ARG B 2 60  ? 122.075 128.654 121.436 1.00 8.14   ? 49  ARG B O     1 
ATOM   1917 C CB    . ARG B 2 60  ? 122.252 125.666 120.495 1.00 2.67   ? 49  ARG B CB    1 
ATOM   1918 C CG    . ARG B 2 60  ? 121.476 124.446 120.029 1.00 7.44   ? 49  ARG B CG    1 
ATOM   1919 C CD    . ARG B 2 60  ? 121.743 123.249 120.925 1.00 8.90   ? 49  ARG B CD    1 
ATOM   1920 N NE    . ARG B 2 60  ? 121.268 122.004 120.334 1.00 4.09   ? 49  ARG B NE    1 
ATOM   1921 C CZ    . ARG B 2 60  ? 120.171 121.364 120.714 1.00 8.44   ? 49  ARG B CZ    1 
ATOM   1922 N NH1   . ARG B 2 60  ? 119.398 121.832 121.680 1.00 10.74  ? 49  ARG B NH1   1 
ATOM   1923 N NH2   . ARG B 2 60  ? 119.842 120.226 120.110 1.00 7.10   ? 49  ARG B NH2   1 
ATOM   1924 N N     . THR B 2 61  ? 123.437 127.606 122.899 1.00 5.62   ? 50  THR B N     1 
ATOM   1925 C CA    . THR B 2 61  ? 124.304 128.752 123.146 1.00 2.05   ? 50  THR B CA    1 
ATOM   1926 C C     . THR B 2 61  ? 125.734 128.333 122.845 1.00 5.81   ? 50  THR B C     1 
ATOM   1927 O O     . THR B 2 61  ? 126.282 127.456 123.522 1.00 8.68   ? 50  THR B O     1 
ATOM   1928 C CB    . THR B 2 61  ? 124.177 129.249 124.587 1.00 3.58   ? 50  THR B CB    1 
ATOM   1929 O OG1   . THR B 2 61  ? 122.807 129.555 124.871 1.00 6.10   ? 50  THR B OG1   1 
ATOM   1930 C CG2   . THR B 2 61  ? 125.020 130.498 124.793 1.00 3.75   ? 50  THR B CG2   1 
ATOM   1931 N N     . LEU B 2 62  ? 126.332 128.953 121.833 1.00 3.04   ? 51  LEU B N     1 
ATOM   1932 C CA    . LEU B 2 62  ? 127.668 128.589 121.375 1.00 1.01   ? 51  LEU B CA    1 
ATOM   1933 C C     . LEU B 2 62  ? 128.689 129.466 122.090 1.00 4.65   ? 51  LEU B C     1 
ATOM   1934 O O     . LEU B 2 62  ? 128.739 130.681 121.871 1.00 8.63   ? 51  LEU B O     1 
ATOM   1935 C CB    . LEU B 2 62  ? 127.772 128.737 119.860 1.00 1.80   ? 51  LEU B CB    1 
ATOM   1936 C CG    . LEU B 2 62  ? 126.692 128.011 119.053 1.00 2.70   ? 51  LEU B CG    1 
ATOM   1937 C CD1   . LEU B 2 62  ? 126.876 128.250 117.564 1.00 2.06   ? 51  LEU B CD1   1 
ATOM   1938 C CD2   . LEU B 2 62  ? 126.690 126.524 119.366 1.00 3.70   ? 51  LEU B CD2   1 
ATOM   1939 N N     . ARG B 2 63  ? 129.504 128.851 122.942 1.00 3.62   ? 52  ARG B N     1 
ATOM   1940 C CA    . ARG B 2 63  ? 130.509 129.550 123.726 1.00 3.37   ? 52  ARG B CA    1 
ATOM   1941 C C     . ARG B 2 63  ? 131.904 129.087 123.326 1.00 3.84   ? 52  ARG B C     1 
ATOM   1942 O O     . ARG B 2 63  ? 132.134 127.903 123.072 1.00 5.43   ? 52  ARG B O     1 
ATOM   1943 C CB    . ARG B 2 63  ? 130.296 129.314 125.224 1.00 4.35   ? 52  ARG B CB    1 
ATOM   1944 C CG    . ARG B 2 63  ? 128.849 129.425 125.673 1.00 5.48   ? 52  ARG B CG    1 
ATOM   1945 C CD    . ARG B 2 63  ? 128.687 128.983 127.119 1.00 5.97   ? 52  ARG B CD    1 
ATOM   1946 N NE    . ARG B 2 63  ? 127.296 128.704 127.453 1.00 6.30   ? 52  ARG B NE    1 
ATOM   1947 C CZ    . ARG B 2 63  ? 126.455 129.590 127.968 1.00 7.69   ? 52  ARG B CZ    1 
ATOM   1948 N NH1   . ARG B 2 63  ? 126.832 130.832 128.225 1.00 5.72   ? 52  ARG B NH1   1 
ATOM   1949 N NH2   . ARG B 2 63  ? 125.205 129.221 128.233 1.00 7.49   ? 52  ARG B NH2   1 
ATOM   1950 N N     . GLY B 2 64  ? 132.843 130.028 123.309 1.00 2.96   ? 53  GLY B N     1 
ATOM   1951 C CA    . GLY B 2 64  ? 134.200 129.725 122.904 1.00 1.48   ? 53  GLY B CA    1 
ATOM   1952 C C     . GLY B 2 64  ? 134.881 130.869 122.185 1.00 4.05   ? 53  GLY B C     1 
ATOM   1953 O O     . GLY B 2 64  ? 136.112 130.913 122.107 1.00 6.30   ? 53  GLY B O     1 
ATOM   1954 N N     . HIS B 2 65  ? 134.096 131.801 121.655 1.00 5.61   ? 54  HIS B N     1 
ATOM   1955 C CA    . HIS B 2 65  ? 134.646 133.058 121.170 1.00 2.99   ? 54  HIS B CA    1 
ATOM   1956 C C     . HIS B 2 65  ? 134.935 133.970 122.354 1.00 4.97   ? 54  HIS B C     1 
ATOM   1957 O O     . HIS B 2 65  ? 134.104 134.124 123.253 1.00 7.48   ? 54  HIS B O     1 
ATOM   1958 C CB    . HIS B 2 65  ? 133.680 133.739 120.202 1.00 1.56   ? 54  HIS B CB    1 
ATOM   1959 C CG    . HIS B 2 65  ? 133.711 133.179 118.814 1.00 2.59   ? 54  HIS B CG    1 
ATOM   1960 N ND1   . HIS B 2 65  ? 134.870 133.089 118.074 1.00 4.31   ? 54  HIS B ND1   1 
ATOM   1961 C CD2   . HIS B 2 65  ? 132.723 132.697 118.024 1.00 2.61   ? 54  HIS B CD2   1 
ATOM   1962 C CE1   . HIS B 2 65  ? 134.595 132.573 116.890 1.00 0.00   ? 54  HIS B CE1   1 
ATOM   1963 N NE2   . HIS B 2 65  ? 133.300 132.322 116.835 1.00 1.15   ? 54  HIS B NE2   1 
ATOM   1964 N N     . LEU B 2 66  ? 136.124 134.568 122.358 1.00 3.62   ? 55  LEU B N     1 
ATOM   1965 C CA    . LEU B 2 66  ? 136.571 135.389 123.475 1.00 5.23   ? 55  LEU B CA    1 
ATOM   1966 C C     . LEU B 2 66  ? 136.600 136.876 123.144 1.00 8.08   ? 55  LEU B C     1 
ATOM   1967 O O     . LEU B 2 66  ? 137.114 137.668 123.940 1.00 10.63  ? 55  LEU B O     1 
ATOM   1968 C CB    . LEU B 2 66  ? 137.948 134.921 123.950 1.00 3.42   ? 55  LEU B CB    1 
ATOM   1969 C CG    . LEU B 2 66  ? 137.938 133.531 124.589 1.00 6.17   ? 55  LEU B CG    1 
ATOM   1970 C CD1   . LEU B 2 66  ? 139.344 133.063 124.903 1.00 4.99   ? 55  LEU B CD1   1 
ATOM   1971 C CD2   . LEU B 2 66  ? 137.076 133.528 125.841 1.00 4.13   ? 55  LEU B CD2   1 
ATOM   1972 N N     . ALA B 2 67  ? 136.062 137.274 121.993 1.00 6.26   ? 56  ALA B N     1 
ATOM   1973 C CA    . ALA B 2 67  ? 135.982 138.674 121.610 1.00 3.08   ? 56  ALA B CA    1 
ATOM   1974 C C     . ALA B 2 67  ? 134.635 138.919 120.946 1.00 3.95   ? 56  ALA B C     1 
ATOM   1975 O O     . ALA B 2 67  ? 133.797 138.018 120.845 1.00 4.33   ? 56  ALA B O     1 
ATOM   1976 C CB    . ALA B 2 67  ? 137.139 139.066 120.685 1.00 2.50   ? 56  ALA B CB    1 
ATOM   1977 N N     . LYS B 2 68  ? 134.426 140.151 120.491 1.00 3.65   ? 57  LYS B N     1 
ATOM   1978 C CA    . LYS B 2 68  ? 133.181 140.496 119.820 1.00 2.36   ? 57  LYS B CA    1 
ATOM   1979 C C     . LYS B 2 68  ? 133.061 139.727 118.511 1.00 4.12   ? 57  LYS B C     1 
ATOM   1980 O O     . LYS B 2 68  ? 133.987 139.716 117.695 1.00 3.29   ? 57  LYS B O     1 
ATOM   1981 C CB    . LYS B 2 68  ? 133.116 142.001 119.565 1.00 3.13   ? 57  LYS B CB    1 
ATOM   1982 C CG    . LYS B 2 68  ? 133.246 142.844 120.822 1.00 6.13   ? 57  LYS B CG    1 
ATOM   1983 C CD    . LYS B 2 68  ? 132.779 144.271 120.593 1.00 4.17   ? 57  LYS B CD    1 
ATOM   1984 C CE    . LYS B 2 68  ? 133.742 145.032 119.697 1.00 3.75   ? 57  LYS B CE    1 
ATOM   1985 N NZ    . LYS B 2 68  ? 133.309 146.440 119.488 1.00 3.35   ? 57  LYS B NZ    1 
ATOM   1986 N N     . ILE B 2 69  ? 131.917 139.083 118.314 1.00 2.28   ? 58  ILE B N     1 
ATOM   1987 C CA    . ILE B 2 69  ? 131.657 138.301 117.113 1.00 3.03   ? 58  ILE B CA    1 
ATOM   1988 C C     . ILE B 2 69  ? 131.050 139.218 116.063 1.00 1.68   ? 58  ILE B C     1 
ATOM   1989 O O     . ILE B 2 69  ? 130.046 139.892 116.320 1.00 3.85   ? 58  ILE B O     1 
ATOM   1990 C CB    . ILE B 2 69  ? 130.729 137.117 117.422 1.00 4.00   ? 58  ILE B CB    1 
ATOM   1991 C CG1   . ILE B 2 69  ? 131.452 136.114 118.316 1.00 2.61   ? 58  ILE B CG1   1 
ATOM   1992 C CG2   . ILE B 2 69  ? 130.258 136.455 116.137 1.00 2.24   ? 58  ILE B CG2   1 
ATOM   1993 C CD1   . ILE B 2 69  ? 130.531 135.262 119.122 1.00 1.40   ? 58  ILE B CD1   1 
ATOM   1994 N N     . TYR B 2 70  ? 131.656 139.246 114.878 1.00 0.35   ? 59  TYR B N     1 
ATOM   1995 C CA    . TYR B 2 70  ? 131.259 140.201 113.854 1.00 1.45   ? 59  TYR B CA    1 
ATOM   1996 C C     . TYR B 2 70  ? 130.456 139.595 112.717 1.00 2.24   ? 59  TYR B C     1 
ATOM   1997 O O     . TYR B 2 70  ? 129.663 140.305 112.097 1.00 2.65   ? 59  TYR B O     1 
ATOM   1998 C CB    . TYR B 2 70  ? 132.494 140.901 113.273 1.00 1.45   ? 59  TYR B CB    1 
ATOM   1999 C CG    . TYR B 2 70  ? 132.793 142.225 113.938 1.00 2.34   ? 59  TYR B CG    1 
ATOM   2000 C CD1   . TYR B 2 70  ? 133.063 142.294 115.298 1.00 1.79   ? 59  TYR B CD1   1 
ATOM   2001 C CD2   . TYR B 2 70  ? 132.794 143.406 113.210 1.00 1.95   ? 59  TYR B CD2   1 
ATOM   2002 C CE1   . TYR B 2 70  ? 133.331 143.500 115.912 1.00 2.34   ? 59  TYR B CE1   1 
ATOM   2003 C CE2   . TYR B 2 70  ? 133.061 144.617 113.815 1.00 2.90   ? 59  TYR B CE2   1 
ATOM   2004 C CZ    . TYR B 2 70  ? 133.330 144.658 115.166 1.00 5.79   ? 59  TYR B CZ    1 
ATOM   2005 O OH    . TYR B 2 70  ? 133.596 145.862 115.774 1.00 7.36   ? 59  TYR B OH    1 
ATOM   2006 N N     . ALA B 2 71  ? 130.629 138.308 112.431 1.00 0.00   ? 60  ALA B N     1 
ATOM   2007 C CA    . ALA B 2 71  ? 129.940 137.693 111.310 1.00 0.00   ? 60  ALA B CA    1 
ATOM   2008 C C     . ALA B 2 71  ? 129.627 136.243 111.637 1.00 0.08   ? 60  ALA B C     1 
ATOM   2009 O O     . ALA B 2 71  ? 130.207 135.648 112.548 1.00 1.38   ? 60  ALA B O     1 
ATOM   2010 C CB    . ALA B 2 71  ? 130.766 137.778 110.025 1.00 3.22   ? 60  ALA B CB    1 
ATOM   2011 N N     . MET B 2 72  ? 128.694 135.684 110.872 1.00 0.02   ? 61  MET B N     1 
ATOM   2012 C CA    . MET B 2 72  ? 128.249 134.311 111.044 1.00 0.00   ? 61  MET B CA    1 
ATOM   2013 C C     . MET B 2 72  ? 127.434 133.914 109.825 1.00 4.31   ? 61  MET B C     1 
ATOM   2014 O O     . MET B 2 72  ? 126.588 134.684 109.367 1.00 7.70   ? 61  MET B O     1 
ATOM   2015 C CB    . MET B 2 72  ? 127.421 134.160 112.327 1.00 1.16   ? 61  MET B CB    1 
ATOM   2016 C CG    . MET B 2 72  ? 126.584 132.905 112.406 1.00 3.67   ? 61  MET B CG    1 
ATOM   2017 S SD    . MET B 2 72  ? 124.900 133.179 111.832 1.00 7.33   ? 61  MET B SD    1 
ATOM   2018 C CE    . MET B 2 72  ? 124.462 134.591 112.836 1.00 6.22   ? 61  MET B CE    1 
ATOM   2019 N N     . HIS B 2 73  ? 127.698 132.718 109.301 1.00 0.00   ? 62  HIS B N     1 
ATOM   2020 C CA    . HIS B 2 73  ? 126.981 132.217 108.137 1.00 0.85   ? 62  HIS B CA    1 
ATOM   2021 C C     . HIS B 2 73  ? 126.602 130.761 108.354 1.00 0.00   ? 62  HIS B C     1 
ATOM   2022 O O     . HIS B 2 73  ? 127.420 129.966 108.826 1.00 0.76   ? 62  HIS B O     1 
ATOM   2023 C CB    . HIS B 2 73  ? 127.818 132.358 106.862 1.00 0.00   ? 62  HIS B CB    1 
ATOM   2024 C CG    . HIS B 2 73  ? 127.007 132.318 105.605 1.00 0.00   ? 62  HIS B CG    1 
ATOM   2025 N ND1   . HIS B 2 73  ? 127.549 132.012 104.377 1.00 0.00   ? 62  HIS B ND1   1 
ATOM   2026 C CD2   . HIS B 2 73  ? 125.688 132.536 105.389 1.00 0.00   ? 62  HIS B CD2   1 
ATOM   2027 C CE1   . HIS B 2 73  ? 126.602 132.048 103.458 1.00 0.00   ? 62  HIS B CE1   1 
ATOM   2028 N NE2   . HIS B 2 73  ? 125.463 132.363 104.046 1.00 0.31   ? 62  HIS B NE2   1 
ATOM   2029 N N     . TRP B 2 74  ? 125.364 130.422 108.011 1.00 2.38   ? 63  TRP B N     1 
ATOM   2030 C CA    . TRP B 2 74  ? 124.890 129.051 108.105 1.00 1.96   ? 63  TRP B CA    1 
ATOM   2031 C C     . TRP B 2 74  ? 125.397 128.221 106.933 1.00 0.34   ? 63  TRP B C     1 
ATOM   2032 O O     . TRP B 2 74  ? 125.632 128.734 105.835 1.00 1.01   ? 63  TRP B O     1 
ATOM   2033 C CB    . TRP B 2 74  ? 123.361 129.012 108.127 1.00 0.62   ? 63  TRP B CB    1 
ATOM   2034 C CG    . TRP B 2 74  ? 122.753 129.153 109.484 1.00 0.43   ? 63  TRP B CG    1 
ATOM   2035 C CD1   . TRP B 2 74  ? 122.087 130.237 109.971 1.00 0.00   ? 63  TRP B CD1   1 
ATOM   2036 C CD2   . TRP B 2 74  ? 122.738 128.172 110.526 1.00 1.34   ? 63  TRP B CD2   1 
ATOM   2037 N NE1   . TRP B 2 74  ? 121.662 129.996 111.253 1.00 0.00   ? 63  TRP B NE1   1 
ATOM   2038 C CE2   . TRP B 2 74  ? 122.052 128.736 111.619 1.00 3.36   ? 63  TRP B CE2   1 
ATOM   2039 C CE3   . TRP B 2 74  ? 123.244 126.874 110.644 1.00 0.00   ? 63  TRP B CE3   1 
ATOM   2040 C CZ2   . TRP B 2 74  ? 121.855 128.046 112.812 1.00 2.12   ? 63  TRP B CZ2   1 
ATOM   2041 C CZ3   . TRP B 2 74  ? 123.048 126.192 111.829 1.00 0.52   ? 63  TRP B CZ3   1 
ATOM   2042 C CH2   . TRP B 2 74  ? 122.359 126.779 112.897 1.00 1.20   ? 63  TRP B CH2   1 
ATOM   2043 N N     . GLY B 2 75  ? 125.570 126.924 107.179 1.00 1.54   ? 64  GLY B N     1 
ATOM   2044 C CA    . GLY B 2 75  ? 125.793 125.995 106.096 1.00 0.00   ? 64  GLY B CA    1 
ATOM   2045 C C     . GLY B 2 75  ? 124.494 125.560 105.446 1.00 0.24   ? 64  GLY B C     1 
ATOM   2046 O O     . GLY B 2 75  ? 123.415 125.644 106.030 1.00 3.86   ? 64  GLY B O     1 
ATOM   2047 N N     . THR B 2 76  ? 124.603 125.088 104.203 1.00 0.80   ? 65  THR B N     1 
ATOM   2048 C CA    . THR B 2 76  ? 123.418 124.639 103.482 1.00 2.42   ? 65  THR B CA    1 
ATOM   2049 C C     . THR B 2 76  ? 122.827 123.361 104.064 1.00 3.65   ? 65  THR B C     1 
ATOM   2050 O O     . THR B 2 76  ? 121.671 123.041 103.770 1.00 6.58   ? 65  THR B O     1 
ATOM   2051 C CB    . THR B 2 76  ? 123.742 124.443 102.002 1.00 3.23   ? 65  THR B CB    1 
ATOM   2052 O OG1   . THR B 2 76  ? 124.754 123.439 101.864 1.00 8.56   ? 65  THR B OG1   1 
ATOM   2053 C CG2   . THR B 2 76  ? 124.212 125.750 101.377 1.00 0.59   ? 65  THR B CG2   1 
ATOM   2054 N N     . ASP B 2 77  ? 123.584 122.630 104.878 1.00 0.00   ? 66  ASP B N     1 
ATOM   2055 C CA    . ASP B 2 77  ? 123.038 121.485 105.593 1.00 1.23   ? 66  ASP B CA    1 
ATOM   2056 C C     . ASP B 2 77  ? 122.215 121.894 106.805 1.00 3.47   ? 66  ASP B C     1 
ATOM   2057 O O     . ASP B 2 77  ? 121.630 121.023 107.458 1.00 6.47   ? 66  ASP B O     1 
ATOM   2058 C CB    . ASP B 2 77  ? 124.163 120.545 106.030 1.00 4.22   ? 66  ASP B CB    1 
ATOM   2059 C CG    . ASP B 2 77  ? 125.116 121.193 107.014 1.00 4.57   ? 66  ASP B CG    1 
ATOM   2060 O OD1   . ASP B 2 77  ? 125.180 122.439 107.063 1.00 3.91   ? 66  ASP B OD1   1 
ATOM   2061 O OD2   . ASP B 2 77  ? 125.797 120.448 107.748 1.00 6.32   ? 66  ASP B OD2   1 
ATOM   2062 N N     . SER B 2 78  ? 122.178 123.190 107.123 1.00 2.93   ? 67  SER B N     1 
ATOM   2063 C CA    . SER B 2 78  ? 121.418 123.745 108.241 1.00 0.69   ? 67  SER B CA    1 
ATOM   2064 C C     . SER B 2 78  ? 121.901 123.219 109.586 1.00 2.73   ? 67  SER B C     1 
ATOM   2065 O O     . SER B 2 78  ? 121.192 123.329 110.590 1.00 6.97   ? 67  SER B O     1 
ATOM   2066 C CB    . SER B 2 78  ? 119.916 123.486 108.078 1.00 1.39   ? 67  SER B CB    1 
ATOM   2067 O OG    . SER B 2 78  ? 119.471 123.890 106.796 1.00 4.57   ? 67  SER B OG    1 
ATOM   2068 N N     . ARG B 2 79  ? 123.097 122.646 109.623 1.00 0.00   ? 68  ARG B N     1 
ATOM   2069 C CA    . ARG B 2 79  ? 123.691 122.143 110.854 1.00 1.13   ? 68  ARG B CA    1 
ATOM   2070 C C     . ARG B 2 79  ? 125.058 122.739 111.143 1.00 3.25   ? 68  ARG B C     1 
ATOM   2071 O O     . ARG B 2 79  ? 125.347 123.077 112.293 1.00 2.79   ? 68  ARG B O     1 
ATOM   2072 C CB    . ARG B 2 79  ? 123.800 120.613 110.795 1.00 1.11   ? 68  ARG B CB    1 
ATOM   2073 C CG    . ARG B 2 79  ? 124.383 119.992 112.042 1.00 1.04   ? 68  ARG B CG    1 
ATOM   2074 C CD    . ARG B 2 79  ? 124.179 118.492 112.061 1.00 2.32   ? 68  ARG B CD    1 
ATOM   2075 N NE    . ARG B 2 79  ? 124.769 117.885 113.247 1.00 0.10   ? 68  ARG B NE    1 
ATOM   2076 C CZ    . ARG B 2 79  ? 124.542 116.641 113.643 1.00 0.32   ? 68  ARG B CZ    1 
ATOM   2077 N NH1   . ARG B 2 79  ? 123.741 115.837 112.965 1.00 3.40   ? 68  ARG B NH1   1 
ATOM   2078 N NH2   . ARG B 2 79  ? 125.132 116.194 114.747 1.00 0.64   ? 68  ARG B NH2   1 
ATOM   2079 N N     . LEU B 2 80  ? 125.905 122.885 110.128 1.00 0.76   ? 69  LEU B N     1 
ATOM   2080 C CA    . LEU B 2 80  ? 127.213 123.494 110.314 1.00 0.59   ? 69  LEU B CA    1 
ATOM   2081 C C     . LEU B 2 80  ? 127.101 125.008 110.214 1.00 1.51   ? 69  LEU B C     1 
ATOM   2082 O O     . LEU B 2 80  ? 126.429 125.539 109.325 1.00 1.90   ? 69  LEU B O     1 
ATOM   2083 C CB    . LEU B 2 80  ? 128.202 122.964 109.277 1.00 2.33   ? 69  LEU B CB    1 
ATOM   2084 C CG    . LEU B 2 80  ? 128.634 121.511 109.473 1.00 0.11   ? 69  LEU B CG    1 
ATOM   2085 C CD1   . LEU B 2 80  ? 129.364 120.993 108.248 1.00 0.00   ? 69  LEU B CD1   1 
ATOM   2086 C CD2   . LEU B 2 80  ? 129.501 121.380 110.711 1.00 0.66   ? 69  LEU B CD2   1 
ATOM   2087 N N     . LEU B 2 81  ? 127.763 125.705 111.134 1.00 1.51   ? 70  LEU B N     1 
ATOM   2088 C CA    . LEU B 2 81  ? 127.609 127.151 111.258 1.00 0.00   ? 70  LEU B CA    1 
ATOM   2089 C C     . LEU B 2 81  ? 128.967 127.783 111.516 1.00 3.07   ? 70  LEU B C     1 
ATOM   2090 O O     . LEU B 2 81  ? 129.612 127.468 112.516 1.00 4.15   ? 70  LEU B O     1 
ATOM   2091 C CB    . LEU B 2 81  ? 126.634 127.486 112.390 1.00 2.30   ? 70  LEU B CB    1 
ATOM   2092 C CG    . LEU B 2 81  ? 126.398 128.952 112.735 1.00 3.22   ? 70  LEU B CG    1 
ATOM   2093 C CD1   . LEU B 2 81  ? 125.641 129.628 111.615 1.00 5.26   ? 70  LEU B CD1   1 
ATOM   2094 C CD2   . LEU B 2 81  ? 125.632 129.055 114.038 1.00 2.44   ? 70  LEU B CD2   1 
ATOM   2095 N N     . VAL B 2 82  ? 129.398 128.680 110.639 1.00 0.99   ? 71  VAL B N     1 
ATOM   2096 C CA    . VAL B 2 82  ? 130.684 129.351 110.796 1.00 1.59   ? 71  VAL B CA    1 
ATOM   2097 C C     . VAL B 2 82  ? 130.459 130.719 111.424 1.00 0.23   ? 71  VAL B C     1 
ATOM   2098 O O     . VAL B 2 82  ? 129.459 131.392 111.142 1.00 2.88   ? 71  VAL B O     1 
ATOM   2099 C CB    . VAL B 2 82  ? 131.433 129.463 109.452 1.00 1.58   ? 71  VAL B CB    1 
ATOM   2100 C CG1   . VAL B 2 82  ? 130.711 130.397 108.490 1.00 1.20   ? 71  VAL B CG1   1 
ATOM   2101 C CG2   . VAL B 2 82  ? 132.863 129.925 109.685 1.00 1.16   ? 71  VAL B CG2   1 
ATOM   2102 N N     . SER B 2 83  ? 131.375 131.118 112.304 1.00 2.37   ? 72  SER B N     1 
ATOM   2103 C CA    . SER B 2 83  ? 131.327 132.422 112.948 1.00 1.04   ? 72  SER B CA    1 
ATOM   2104 C C     . SER B 2 83  ? 132.730 133.005 113.003 1.00 0.00   ? 72  SER B C     1 
ATOM   2105 O O     . SER B 2 83  ? 133.720 132.275 113.098 1.00 0.91   ? 72  SER B O     1 
ATOM   2106 C CB    . SER B 2 83  ? 130.736 132.338 114.362 1.00 0.00   ? 72  SER B CB    1 
ATOM   2107 O OG    . SER B 2 83  ? 131.519 131.503 115.196 1.00 3.26   ? 72  SER B OG    1 
ATOM   2108 N N     . ALA B 2 84  ? 132.805 134.332 112.945 1.00 1.07   ? 73  ALA B N     1 
ATOM   2109 C CA    . ALA B 2 84  ? 134.067 135.059 112.947 1.00 0.54   ? 73  ALA B CA    1 
ATOM   2110 C C     . ALA B 2 84  ? 134.090 136.022 114.123 1.00 0.00   ? 73  ALA B C     1 
ATOM   2111 O O     . ALA B 2 84  ? 133.119 136.756 114.347 1.00 1.72   ? 73  ALA B O     1 
ATOM   2112 C CB    . ALA B 2 84  ? 134.266 135.823 111.636 1.00 1.31   ? 73  ALA B CB    1 
ATOM   2113 N N     . SER B 2 85  ? 135.195 136.030 114.867 1.00 0.00   ? 74  SER B N     1 
ATOM   2114 C CA    . SER B 2 85  ? 135.317 136.913 116.016 1.00 0.61   ? 74  SER B CA    1 
ATOM   2115 C C     . SER B 2 85  ? 136.594 137.735 115.913 1.00 3.25   ? 74  SER B C     1 
ATOM   2116 O O     . SER B 2 85  ? 137.536 137.378 115.202 1.00 2.69   ? 74  SER B O     1 
ATOM   2117 C CB    . SER B 2 85  ? 135.298 136.133 117.334 1.00 0.50   ? 74  SER B CB    1 
ATOM   2118 O OG    . SER B 2 85  ? 135.730 136.941 118.413 1.00 2.39   ? 74  SER B OG    1 
ATOM   2119 N N     . GLN B 2 86  ? 136.606 138.854 116.641 1.00 4.41   ? 75  GLN B N     1 
ATOM   2120 C CA    . GLN B 2 86  ? 137.731 139.779 116.617 1.00 1.66   ? 75  GLN B CA    1 
ATOM   2121 C C     . GLN B 2 86  ? 138.969 139.232 117.313 1.00 3.44   ? 75  GLN B C     1 
ATOM   2122 O O     . GLN B 2 86  ? 140.033 139.852 117.217 1.00 6.57   ? 75  GLN B O     1 
ATOM   2123 C CB    . GLN B 2 86  ? 137.330 141.111 117.252 1.00 5.00   ? 75  GLN B CB    1 
ATOM   2124 C CG    . GLN B 2 86  ? 136.444 141.972 116.370 1.00 7.58   ? 75  GLN B CG    1 
ATOM   2125 C CD    . GLN B 2 86  ? 137.191 142.566 115.193 1.00 4.94   ? 75  GLN B CD    1 
ATOM   2126 O OE1   . GLN B 2 86  ? 138.420 142.588 115.173 1.00 6.89   ? 75  GLN B OE1   1 
ATOM   2127 N NE2   . GLN B 2 86  ? 136.451 143.050 114.203 1.00 2.07   ? 75  GLN B NE2   1 
ATOM   2128 N N     . ASP B 2 87  ? 138.862 138.103 118.009 1.00 2.33   ? 76  ASP B N     1 
ATOM   2129 C CA    . ASP B 2 87  ? 140.021 137.456 118.607 1.00 1.68   ? 76  ASP B CA    1 
ATOM   2130 C C     . ASP B 2 87  ? 140.876 136.720 117.582 1.00 2.18   ? 76  ASP B C     1 
ATOM   2131 O O     . ASP B 2 87  ? 141.759 135.949 117.970 1.00 5.45   ? 76  ASP B O     1 
ATOM   2132 C CB    . ASP B 2 87  ? 139.576 136.490 119.710 1.00 3.07   ? 76  ASP B CB    1 
ATOM   2133 C CG    . ASP B 2 87  ? 138.611 135.432 119.211 1.00 6.10   ? 76  ASP B CG    1 
ATOM   2134 O OD1   . ASP B 2 87  ? 138.254 135.461 118.017 1.00 5.16   ? 76  ASP B OD1   1 
ATOM   2135 O OD2   . ASP B 2 87  ? 138.204 134.570 120.017 1.00 11.08  ? 76  ASP B OD2   1 
ATOM   2136 N N     . GLY B 2 88  ? 140.630 136.939 116.293 1.00 0.02   ? 77  GLY B N     1 
ATOM   2137 C CA    . GLY B 2 88  ? 141.375 136.253 115.259 1.00 1.71   ? 77  GLY B CA    1 
ATOM   2138 C C     . GLY B 2 88  ? 140.964 134.819 115.049 1.00 3.84   ? 77  GLY B C     1 
ATOM   2139 O O     . GLY B 2 88  ? 141.800 133.993 114.669 1.00 7.40   ? 77  GLY B O     1 
ATOM   2140 N N     . LYS B 2 89  ? 139.696 134.494 115.281 1.00 0.31   ? 78  LYS B N     1 
ATOM   2141 C CA    . LYS B 2 89  ? 139.235 133.118 115.219 1.00 0.00   ? 78  LYS B CA    1 
ATOM   2142 C C     . LYS B 2 89  ? 138.038 132.987 114.291 1.00 2.43   ? 78  LYS B C     1 
ATOM   2143 O O     . LYS B 2 89  ? 137.135 133.836 114.282 1.00 3.55   ? 78  LYS B O     1 
ATOM   2144 C CB    . LYS B 2 89  ? 138.870 132.592 116.609 1.00 0.50   ? 78  LYS B CB    1 
ATOM   2145 C CG    . LYS B 2 89  ? 139.193 131.125 116.800 1.00 2.36   ? 78  LYS B CG    1 
ATOM   2146 C CD    . LYS B 2 89  ? 140.687 130.871 116.688 1.00 3.08   ? 78  LYS B CD    1 
ATOM   2147 C CE    . LYS B 2 89  ? 141.469 131.687 117.704 1.00 2.57   ? 78  LYS B CE    1 
ATOM   2148 N NZ    . LYS B 2 89  ? 142.933 131.443 117.600 1.00 6.11   ? 78  LYS B NZ    1 
ATOM   2149 N N     . LEU B 2 90  ? 138.050 131.909 113.508 1.00 0.80   ? 79  LEU B N     1 
ATOM   2150 C CA    . LEU B 2 90  ? 136.932 131.505 112.663 1.00 0.68   ? 79  LEU B CA    1 
ATOM   2151 C C     . LEU B 2 90  ? 136.521 130.108 113.109 1.00 3.52   ? 79  LEU B C     1 
ATOM   2152 O O     . LEU B 2 90  ? 137.230 129.135 112.841 1.00 3.55   ? 79  LEU B O     1 
ATOM   2153 C CB    . LEU B 2 90  ? 137.335 131.530 111.189 1.00 0.00   ? 79  LEU B CB    1 
ATOM   2154 C CG    . LEU B 2 90  ? 136.250 131.477 110.117 1.00 2.60   ? 79  LEU B CG    1 
ATOM   2155 C CD1   . LEU B 2 90  ? 135.461 132.768 110.103 1.00 4.33   ? 79  LEU B CD1   1 
ATOM   2156 C CD2   . LEU B 2 90  ? 136.878 131.225 108.759 1.00 2.49   ? 79  LEU B CD2   1 
ATOM   2157 N N     . ILE B 2 91  ? 135.392 130.004 113.802 1.00 0.00   ? 80  ILE B N     1 
ATOM   2158 C CA    . ILE B 2 91  ? 134.973 128.752 114.424 1.00 0.20   ? 80  ILE B CA    1 
ATOM   2159 C C     . ILE B 2 91  ? 133.809 128.166 113.639 1.00 2.49   ? 80  ILE B C     1 
ATOM   2160 O O     . ILE B 2 91  ? 132.808 128.848 113.393 1.00 0.00   ? 80  ILE B O     1 
ATOM   2161 C CB    . ILE B 2 91  ? 134.597 128.947 115.903 1.00 0.04   ? 80  ILE B CB    1 
ATOM   2162 C CG1   . ILE B 2 91  ? 135.820 129.384 116.710 1.00 0.60   ? 80  ILE B CG1   1 
ATOM   2163 C CG2   . ILE B 2 91  ? 134.024 127.665 116.480 1.00 0.20   ? 80  ILE B CG2   1 
ATOM   2164 C CD1   . ILE B 2 91  ? 135.541 129.567 118.184 1.00 0.62   ? 80  ILE B CD1   1 
ATOM   2165 N N     . ILE B 2 92  ? 133.946 126.903 113.250 1.00 0.00   ? 81  ILE B N     1 
ATOM   2166 C CA    . ILE B 2 92  ? 132.888 126.145 112.597 1.00 0.00   ? 81  ILE B CA    1 
ATOM   2167 C C     . ILE B 2 92  ? 132.273 125.216 113.633 1.00 0.00   ? 81  ILE B C     1 
ATOM   2168 O O     . ILE B 2 92  ? 132.952 124.328 114.164 1.00 1.55   ? 81  ILE B O     1 
ATOM   2169 C CB    . ILE B 2 92  ? 133.418 125.357 111.391 1.00 1.42   ? 81  ILE B CB    1 
ATOM   2170 C CG1   . ILE B 2 92  ? 133.965 126.317 110.336 1.00 0.88   ? 81  ILE B CG1   1 
ATOM   2171 C CG2   . ILE B 2 92  ? 132.322 124.482 110.805 1.00 0.97   ? 81  ILE B CG2   1 
ATOM   2172 C CD1   . ILE B 2 92  ? 134.660 125.630 109.203 1.00 0.88   ? 81  ILE B CD1   1 
ATOM   2173 N N     . TRP B 2 93  ? 130.986 125.425 113.894 1.00 0.00   ? 82  TRP B N     1 
ATOM   2174 C CA    . TRP B 2 93  ? 130.188 124.767 114.914 1.00 3.20   ? 82  TRP B CA    1 
ATOM   2175 C C     . TRP B 2 93  ? 129.295 123.694 114.310 1.00 3.03   ? 82  TRP B C     1 
ATOM   2176 O O     . TRP B 2 93  ? 128.734 123.866 113.223 1.00 4.33   ? 82  TRP B O     1 
ATOM   2177 C CB    . TRP B 2 93  ? 129.291 125.784 115.622 1.00 0.17   ? 82  TRP B CB    1 
ATOM   2178 C CG    . TRP B 2 93  ? 129.980 126.771 116.489 1.00 0.52   ? 82  TRP B CG    1 
ATOM   2179 C CD1   . TRP B 2 93  ? 130.370 128.033 116.150 1.00 1.43   ? 82  TRP B CD1   1 
ATOM   2180 C CD2   . TRP B 2 93  ? 130.286 126.614 117.875 1.00 0.61   ? 82  TRP B CD2   1 
ATOM   2181 N NE1   . TRP B 2 93  ? 130.941 128.657 117.232 1.00 0.90   ? 82  TRP B NE1   1 
ATOM   2182 C CE2   . TRP B 2 93  ? 130.897 127.806 118.305 1.00 1.95   ? 82  TRP B CE2   1 
ATOM   2183 C CE3   . TRP B 2 93  ? 130.118 125.573 118.790 1.00 2.03   ? 82  TRP B CE3   1 
ATOM   2184 C CZ2   . TRP B 2 93  ? 131.342 127.984 119.608 1.00 1.11   ? 82  TRP B CZ2   1 
ATOM   2185 C CZ3   . TRP B 2 93  ? 130.558 125.751 120.079 1.00 3.18   ? 82  TRP B CZ3   1 
ATOM   2186 C CH2   . TRP B 2 93  ? 131.158 126.946 120.477 1.00 4.14   ? 82  TRP B CH2   1 
ATOM   2187 N N     . ASP B 2 94  ? 129.150 122.596 115.047 1.00 0.79   ? 83  ASP B N     1 
ATOM   2188 C CA    . ASP B 2 94  ? 128.056 121.649 114.848 1.00 0.80   ? 83  ASP B CA    1 
ATOM   2189 C C     . ASP B 2 94  ? 126.904 122.143 115.714 1.00 1.00   ? 83  ASP B C     1 
ATOM   2190 O O     . ASP B 2 94  ? 126.891 121.931 116.929 1.00 3.18   ? 83  ASP B O     1 
ATOM   2191 C CB    . ASP B 2 94  ? 128.488 120.235 115.221 1.00 1.60   ? 83  ASP B CB    1 
ATOM   2192 C CG    . ASP B 2 94  ? 127.389 119.210 115.018 1.00 2.78   ? 83  ASP B CG    1 
ATOM   2193 O OD1   . ASP B 2 94  ? 126.336 119.559 114.450 1.00 2.28   ? 83  ASP B OD1   1 
ATOM   2194 O OD2   . ASP B 2 94  ? 127.580 118.047 115.431 1.00 4.30   ? 83  ASP B OD2   1 
ATOM   2195 N N     . SER B 2 95  ? 125.935 122.816 115.090 1.00 1.71   ? 84  SER B N     1 
ATOM   2196 C CA    . SER B 2 95  ? 124.893 123.492 115.856 1.00 0.27   ? 84  SER B CA    1 
ATOM   2197 C C     . SER B 2 95  ? 123.995 122.510 116.596 1.00 2.14   ? 84  SER B C     1 
ATOM   2198 O O     . SER B 2 95  ? 123.423 122.862 117.634 1.00 5.59   ? 84  SER B O     1 
ATOM   2199 C CB    . SER B 2 95  ? 124.057 124.381 114.936 1.00 0.15   ? 84  SER B CB    1 
ATOM   2200 O OG    . SER B 2 95  ? 123.360 123.611 113.974 1.00 1.63   ? 84  SER B OG    1 
ATOM   2201 N N     . TYR B 2 96  ? 123.850 121.286 116.084 1.00 2.97   ? 85  TYR B N     1 
ATOM   2202 C CA    . TYR B 2 96  ? 122.978 120.315 116.738 1.00 0.97   ? 85  TYR B CA    1 
ATOM   2203 C C     . TYR B 2 96  ? 123.528 119.901 118.098 1.00 2.88   ? 85  TYR B C     1 
ATOM   2204 O O     . TYR B 2 96  ? 122.770 119.768 119.065 1.00 8.22   ? 85  TYR B O     1 
ATOM   2205 C CB    . TYR B 2 96  ? 122.788 119.088 115.846 1.00 1.57   ? 85  TYR B CB    1 
ATOM   2206 C CG    . TYR B 2 96  ? 121.822 119.285 114.696 1.00 1.34   ? 85  TYR B CG    1 
ATOM   2207 C CD1   . TYR B 2 96  ? 121.471 120.557 114.263 1.00 1.07   ? 85  TYR B CD1   1 
ATOM   2208 C CD2   . TYR B 2 96  ? 121.264 118.196 114.042 1.00 1.17   ? 85  TYR B CD2   1 
ATOM   2209 C CE1   . TYR B 2 96  ? 120.595 120.737 113.214 1.00 2.51   ? 85  TYR B CE1   1 
ATOM   2210 C CE2   . TYR B 2 96  ? 120.386 118.367 112.990 1.00 2.18   ? 85  TYR B CE2   1 
ATOM   2211 C CZ    . TYR B 2 96  ? 120.055 119.640 112.581 1.00 3.63   ? 85  TYR B CZ    1 
ATOM   2212 O OH    . TYR B 2 96  ? 119.180 119.818 111.535 1.00 6.15   ? 85  TYR B OH    1 
ATOM   2213 N N     . THR B 2 97  ? 124.841 119.698 118.192 1.00 1.14   ? 86  THR B N     1 
ATOM   2214 C CA    . THR B 2 97  ? 125.476 119.215 119.411 1.00 1.05   ? 86  THR B CA    1 
ATOM   2215 C C     . THR B 2 97  ? 126.341 120.272 120.086 1.00 2.05   ? 86  THR B C     1 
ATOM   2216 O O     . THR B 2 97  ? 126.993 119.971 121.092 1.00 2.98   ? 86  THR B O     1 
ATOM   2217 C CB    . THR B 2 97  ? 126.318 117.974 119.107 1.00 3.11   ? 86  THR B CB    1 
ATOM   2218 O OG1   . THR B 2 97  ? 127.408 118.333 118.250 1.00 3.37   ? 86  THR B OG1   1 
ATOM   2219 C CG2   . THR B 2 97  ? 125.474 116.912 118.420 1.00 2.44   ? 86  THR B CG2   1 
ATOM   2220 N N     . THR B 2 98  ? 126.361 121.498 119.559 1.00 2.36   ? 87  THR B N     1 
ATOM   2221 C CA    . THR B 2 98  ? 127.202 122.592 120.049 1.00 1.99   ? 87  THR B CA    1 
ATOM   2222 C C     . THR B 2 98  ? 128.683 122.230 120.046 1.00 3.38   ? 87  THR B C     1 
ATOM   2223 O O     . THR B 2 98  ? 129.473 122.827 120.784 1.00 2.68   ? 87  THR B O     1 
ATOM   2224 C CB    . THR B 2 98  ? 126.781 123.056 121.449 1.00 1.82   ? 87  THR B CB    1 
ATOM   2225 O OG1   . THR B 2 98  ? 127.091 122.041 122.412 1.00 1.72   ? 87  THR B OG1   1 
ATOM   2226 C CG2   . THR B 2 98  ? 125.292 123.347 121.489 1.00 3.13   ? 87  THR B CG2   1 
ATOM   2227 N N     . ASN B 2 99  ? 129.077 121.259 119.227 1.00 0.79   ? 88  ASN B N     1 
ATOM   2228 C CA    . ASN B 2 99  ? 130.475 120.868 119.129 1.00 0.87   ? 88  ASN B CA    1 
ATOM   2229 C C     . ASN B 2 99  ? 131.221 121.798 118.185 1.00 2.94   ? 88  ASN B C     1 
ATOM   2230 O O     . ASN B 2 99  ? 130.682 122.235 117.164 1.00 2.98   ? 88  ASN B O     1 
ATOM   2231 C CB    . ASN B 2 99  ? 130.596 119.425 118.639 1.00 0.67   ? 88  ASN B CB    1 
ATOM   2232 C CG    . ASN B 2 99  ? 130.427 118.414 119.752 1.00 1.08   ? 88  ASN B CG    1 
ATOM   2233 O OD1   . ASN B 2 99  ? 130.627 118.724 120.926 1.00 3.03   ? 88  ASN B OD1   1 
ATOM   2234 N ND2   . ASN B 2 99  ? 130.056 117.193 119.389 1.00 3.33   ? 88  ASN B ND2   1 
ATOM   2235 N N     . LYS B 2 100 ? 132.470 122.096 118.529 1.00 0.00   ? 89  LYS B N     1 
ATOM   2236 C CA    . LYS B 2 100 ? 133.331 122.889 117.662 1.00 0.00   ? 89  LYS B CA    1 
ATOM   2237 C C     . LYS B 2 100 ? 133.958 121.961 116.632 1.00 3.40   ? 89  LYS B C     1 
ATOM   2238 O O     . LYS B 2 100 ? 134.880 121.201 116.948 1.00 0.96   ? 89  LYS B O     1 
ATOM   2239 C CB    . LYS B 2 100 ? 134.400 123.611 118.477 1.00 1.59   ? 89  LYS B CB    1 
ATOM   2240 C CG    . LYS B 2 100 ? 133.855 124.669 119.419 1.00 0.00   ? 89  LYS B CG    1 
ATOM   2241 C CD    . LYS B 2 100 ? 134.977 125.375 120.154 1.00 1.33   ? 89  LYS B CD    1 
ATOM   2242 C CE    . LYS B 2 100 ? 134.452 126.476 121.048 1.00 2.91   ? 89  LYS B CE    1 
ATOM   2243 N NZ    . LYS B 2 100 ? 133.670 125.923 122.185 1.00 1.18   ? 89  LYS B NZ    1 
ATOM   2244 N N     . VAL B 2 101 ? 133.449 122.006 115.400 1.00 0.20   ? 90  VAL B N     1 
ATOM   2245 C CA    . VAL B 2 101 ? 134.003 121.165 114.346 1.00 0.00   ? 90  VAL B CA    1 
ATOM   2246 C C     . VAL B 2 101 ? 135.391 121.651 113.953 1.00 0.00   ? 90  VAL B C     1 
ATOM   2247 O O     . VAL B 2 101 ? 136.320 120.851 113.789 1.00 0.00   ? 90  VAL B O     1 
ATOM   2248 C CB    . VAL B 2 101 ? 133.052 121.123 113.138 1.00 0.00   ? 90  VAL B CB    1 
ATOM   2249 C CG1   . VAL B 2 101 ? 133.618 120.229 112.049 1.00 0.01   ? 90  VAL B CG1   1 
ATOM   2250 C CG2   . VAL B 2 101 ? 131.684 120.635 113.567 1.00 0.00   ? 90  VAL B CG2   1 
ATOM   2251 N N     . HIS B 2 102 ? 135.562 122.963 113.810 1.00 5.25   ? 91  HIS B N     1 
ATOM   2252 C CA    . HIS B 2 102 ? 136.837 123.515 113.376 1.00 1.89   ? 91  HIS B CA    1 
ATOM   2253 C C     . HIS B 2 102 ? 137.107 124.835 114.079 1.00 0.00   ? 91  HIS B C     1 
ATOM   2254 O O     . HIS B 2 102 ? 136.183 125.563 114.443 1.00 2.88   ? 91  HIS B O     1 
ATOM   2255 C CB    . HIS B 2 102 ? 136.875 123.733 111.855 1.00 2.10   ? 91  HIS B CB    1 
ATOM   2256 C CG    . HIS B 2 102 ? 137.030 122.472 111.063 1.00 2.11   ? 91  HIS B CG    1 
ATOM   2257 N ND1   . HIS B 2 102 ? 136.021 121.957 110.278 1.00 1.85   ? 91  HIS B ND1   1 
ATOM   2258 C CD2   . HIS B 2 102 ? 138.077 121.623 110.933 1.00 1.72   ? 91  HIS B CD2   1 
ATOM   2259 C CE1   . HIS B 2 102 ? 136.439 120.846 109.700 1.00 1.47   ? 91  HIS B CE1   1 
ATOM   2260 N NE2   . HIS B 2 102 ? 137.683 120.621 110.081 1.00 0.80   ? 91  HIS B NE2   1 
ATOM   2261 N N     . ALA B 2 103 ? 138.391 125.141 114.252 1.00 2.53   ? 92  ALA B N     1 
ATOM   2262 C CA    . ALA B 2 103 ? 138.838 126.440 114.739 1.00 0.79   ? 92  ALA B CA    1 
ATOM   2263 C C     . ALA B 2 103 ? 140.012 126.881 113.881 1.00 1.39   ? 92  ALA B C     1 
ATOM   2264 O O     . ALA B 2 103 ? 141.070 126.243 113.900 1.00 2.39   ? 92  ALA B O     1 
ATOM   2265 C CB    . ALA B 2 103 ? 139.236 126.383 116.215 1.00 0.00   ? 92  ALA B CB    1 
ATOM   2266 N N     . ILE B 2 104 ? 139.829 127.960 113.134 1.00 2.38   ? 93  ILE B N     1 
ATOM   2267 C CA    . ILE B 2 104 ? 140.810 128.455 112.176 1.00 0.86   ? 93  ILE B CA    1 
ATOM   2268 C C     . ILE B 2 104 ? 141.417 129.734 112.740 1.00 1.13   ? 93  ILE B C     1 
ATOM   2269 O O     . ILE B 2 104 ? 140.690 130.717 112.952 1.00 0.00   ? 93  ILE B O     1 
ATOM   2270 C CB    . ILE B 2 104 ? 140.177 128.705 110.799 1.00 3.06   ? 93  ILE B CB    1 
ATOM   2271 C CG1   . ILE B 2 104 ? 139.340 127.497 110.376 1.00 0.00   ? 93  ILE B CG1   1 
ATOM   2272 C CG2   . ILE B 2 104 ? 141.251 129.001 109.766 1.00 1.78   ? 93  ILE B CG2   1 
ATOM   2273 C CD1   . ILE B 2 104 ? 138.153 127.847 109.514 1.00 0.19   ? 93  ILE B CD1   1 
ATOM   2274 N N     . PRO B 2 105 ? 142.718 129.760 113.027 1.00 8.24   ? 94  PRO B N     1 
ATOM   2275 C CA    . PRO B 2 105 ? 143.370 131.028 113.366 1.00 6.26   ? 94  PRO B CA    1 
ATOM   2276 C C     . PRO B 2 105 ? 143.536 131.888 112.125 1.00 4.06   ? 94  PRO B C     1 
ATOM   2277 O O     . PRO B 2 105 ? 143.936 131.408 111.061 1.00 4.12   ? 94  PRO B O     1 
ATOM   2278 C CB    . PRO B 2 105 ? 144.730 130.594 113.933 1.00 4.51   ? 94  PRO B CB    1 
ATOM   2279 C CG    . PRO B 2 105 ? 144.641 129.099 114.112 1.00 2.50   ? 94  PRO B CG    1 
ATOM   2280 C CD    . PRO B 2 105 ? 143.647 128.624 113.110 1.00 4.35   ? 94  PRO B CD    1 
ATOM   2281 N N     . LEU B 2 106 ? 143.230 133.171 112.270 1.00 1.11   ? 95  LEU B N     1 
ATOM   2282 C CA    . LEU B 2 106 ? 143.265 134.109 111.159 1.00 3.62   ? 95  LEU B CA    1 
ATOM   2283 C C     . LEU B 2 106 ? 144.521 134.965 111.236 1.00 6.65   ? 95  LEU B C     1 
ATOM   2284 O O     . LEU B 2 106 ? 144.944 135.368 112.323 1.00 11.65  ? 95  LEU B O     1 
ATOM   2285 C CB    . LEU B 2 106 ? 142.018 134.993 111.165 1.00 1.38   ? 95  LEU B CB    1 
ATOM   2286 C CG    . LEU B 2 106 ? 140.703 134.224 111.311 1.00 1.14   ? 95  LEU B CG    1 
ATOM   2287 C CD1   . LEU B 2 106 ? 139.533 135.170 111.488 1.00 0.00   ? 95  LEU B CD1   1 
ATOM   2288 C CD2   . LEU B 2 106 ? 140.482 133.315 110.115 1.00 2.83   ? 95  LEU B CD2   1 
ATOM   2289 N N     . ARG B 2 107 ? 145.121 135.228 110.072 1.00 1.92   ? 96  ARG B N     1 
ATOM   2290 C CA    . ARG B 2 107 ? 146.308 136.076 110.030 1.00 2.72   ? 96  ARG B CA    1 
ATOM   2291 C C     . ARG B 2 107 ? 145.991 137.483 110.518 1.00 6.13   ? 96  ARG B C     1 
ATOM   2292 O O     . ARG B 2 107 ? 146.794 138.099 111.228 1.00 12.77  ? 96  ARG B O     1 
ATOM   2293 C CB    . ARG B 2 107 ? 146.877 136.115 108.612 1.00 7.34   ? 96  ARG B CB    1 
ATOM   2294 C CG    . ARG B 2 107 ? 147.649 134.869 108.215 1.00 7.12   ? 96  ARG B CG    1 
ATOM   2295 C CD    . ARG B 2 107 ? 147.893 134.832 106.714 1.00 7.83   ? 96  ARG B CD    1 
ATOM   2296 N NE    . ARG B 2 107 ? 148.872 133.821 106.332 1.00 12.61  ? 96  ARG B NE    1 
ATOM   2297 C CZ    . ARG B 2 107 ? 148.637 132.516 106.313 1.00 13.69  ? 96  ARG B CZ    1 
ATOM   2298 N NH1   . ARG B 2 107 ? 147.458 132.020 106.649 1.00 11.40  ? 96  ARG B NH1   1 
ATOM   2299 N NH2   . ARG B 2 107 ? 149.610 131.688 105.944 1.00 8.82   ? 96  ARG B NH2   1 
ATOM   2300 N N     . SER B 2 108 ? 144.826 138.006 110.148 1.00 3.70   ? 97  SER B N     1 
ATOM   2301 C CA    . SER B 2 108 ? 144.348 139.297 110.621 1.00 2.16   ? 97  SER B CA    1 
ATOM   2302 C C     . SER B 2 108 ? 143.166 139.061 111.551 1.00 4.24   ? 97  SER B C     1 
ATOM   2303 O O     . SER B 2 108 ? 142.191 138.407 111.166 1.00 7.34   ? 97  SER B O     1 
ATOM   2304 C CB    . SER B 2 108 ? 143.948 140.197 109.453 1.00 2.98   ? 97  SER B CB    1 
ATOM   2305 O OG    . SER B 2 108 ? 143.711 141.524 109.889 1.00 5.62   ? 97  SER B OG    1 
ATOM   2306 N N     . SER B 2 109 ? 143.257 139.587 112.770 1.00 0.92   ? 98  SER B N     1 
ATOM   2307 C CA    . SER B 2 109 ? 142.193 139.424 113.751 1.00 0.50   ? 98  SER B CA    1 
ATOM   2308 C C     . SER B 2 109 ? 141.048 140.406 113.555 1.00 3.30   ? 98  SER B C     1 
ATOM   2309 O O     . SER B 2 109 ? 140.026 140.287 114.238 1.00 4.19   ? 98  SER B O     1 
ATOM   2310 C CB    . SER B 2 109 ? 142.758 139.571 115.166 1.00 1.76   ? 98  SER B CB    1 
ATOM   2311 O OG    . SER B 2 109 ? 143.493 140.775 115.300 1.00 6.66   ? 98  SER B OG    1 
ATOM   2312 N N     . TRP B 2 110 ? 141.193 141.365 112.644 1.00 3.39   ? 99  TRP B N     1 
ATOM   2313 C CA    . TRP B 2 110 ? 140.183 142.401 112.435 1.00 2.35   ? 99  TRP B CA    1 
ATOM   2314 C C     . TRP B 2 110 ? 139.234 142.007 111.303 1.00 2.59   ? 99  TRP B C     1 
ATOM   2315 O O     . TRP B 2 110 ? 139.154 142.650 110.258 1.00 4.39   ? 99  TRP B O     1 
ATOM   2316 C CB    . TRP B 2 110 ? 140.862 143.736 112.158 1.00 2.38   ? 99  TRP B CB    1 
ATOM   2317 C CG    . TRP B 2 110 ? 141.935 144.052 113.145 1.00 1.86   ? 99  TRP B CG    1 
ATOM   2318 C CD1   . TRP B 2 110 ? 143.281 143.970 112.947 1.00 1.68   ? 99  TRP B CD1   1 
ATOM   2319 C CD2   . TRP B 2 110 ? 141.755 144.491 114.496 1.00 0.23   ? 99  TRP B CD2   1 
ATOM   2320 N NE1   . TRP B 2 110 ? 143.951 144.335 114.088 1.00 0.15   ? 99  TRP B NE1   1 
ATOM   2321 C CE2   . TRP B 2 110 ? 143.036 144.659 115.054 1.00 0.79   ? 99  TRP B CE2   1 
ATOM   2322 C CE3   . TRP B 2 110 ? 140.634 144.760 115.286 1.00 0.00   ? 99  TRP B CE3   1 
ATOM   2323 C CZ2   . TRP B 2 110 ? 143.227 145.084 116.366 1.00 3.00   ? 99  TRP B CZ2   1 
ATOM   2324 C CZ3   . TRP B 2 110 ? 140.826 145.181 116.587 1.00 2.22   ? 99  TRP B CZ3   1 
ATOM   2325 C CH2   . TRP B 2 110 ? 142.112 145.340 117.114 1.00 3.73   ? 99  TRP B CH2   1 
ATOM   2326 N N     . VAL B 2 111 ? 138.505 140.924 111.534 1.00 2.08   ? 100 VAL B N     1 
ATOM   2327 C CA    . VAL B 2 111 ? 137.582 140.384 110.544 1.00 2.34   ? 100 VAL B CA    1 
ATOM   2328 C C     . VAL B 2 111 ? 136.181 140.913 110.809 1.00 2.76   ? 100 VAL B C     1 
ATOM   2329 O O     . VAL B 2 111 ? 135.716 140.964 111.954 1.00 4.42   ? 100 VAL B O     1 
ATOM   2330 C CB    . VAL B 2 111 ? 137.611 138.844 110.545 1.00 2.70   ? 100 VAL B CB    1 
ATOM   2331 C CG1   . VAL B 2 111 ? 138.919 138.350 109.949 1.00 3.49   ? 100 VAL B CG1   1 
ATOM   2332 C CG2   . VAL B 2 111 ? 137.426 138.304 111.953 1.00 0.08   ? 100 VAL B CG2   1 
ATOM   2333 N N     . MET B 2 112 ? 135.509 141.322 109.734 1.00 3.08   ? 101 MET B N     1 
ATOM   2334 C CA    . MET B 2 112 ? 134.154 141.837 109.795 1.00 2.35   ? 101 MET B CA    1 
ATOM   2335 C C     . MET B 2 112 ? 133.147 140.982 109.042 1.00 1.76   ? 101 MET B C     1 
ATOM   2336 O O     . MET B 2 112 ? 131.941 141.191 109.210 1.00 3.93   ? 101 MET B O     1 
ATOM   2337 C CB    . MET B 2 112 ? 134.102 143.269 109.239 1.00 2.90   ? 101 MET B CB    1 
ATOM   2338 C CG    . MET B 2 112 ? 135.065 144.230 109.912 1.00 1.47   ? 101 MET B CG    1 
ATOM   2339 S SD    . MET B 2 112 ? 135.113 145.838 109.100 1.00 10.68  ? 101 MET B SD    1 
ATOM   2340 C CE    . MET B 2 112 ? 133.743 146.662 109.906 1.00 1.15   ? 101 MET B CE    1 
ATOM   2341 N N     . THR B 2 113 ? 133.598 140.034 108.222 1.00 0.51   ? 102 THR B N     1 
ATOM   2342 C CA    . THR B 2 113 ? 132.700 139.202 107.438 1.00 2.95   ? 102 THR B CA    1 
ATOM   2343 C C     . THR B 2 113 ? 133.234 137.779 107.377 1.00 6.02   ? 102 THR B C     1 
ATOM   2344 O O     . THR B 2 113 ? 134.433 137.532 107.523 1.00 3.52   ? 102 THR B O     1 
ATOM   2345 C CB    . THR B 2 113 ? 132.512 139.747 106.017 1.00 3.19   ? 102 THR B CB    1 
ATOM   2346 O OG1   . THR B 2 113 ? 131.573 138.925 105.313 1.00 4.39   ? 102 THR B OG1   1 
ATOM   2347 C CG2   . THR B 2 113 ? 133.836 139.759 105.265 1.00 1.95   ? 102 THR B CG2   1 
ATOM   2348 N N     . CYS B 2 114 ? 132.315 136.839 107.164 1.00 4.72   ? 103 CYS B N     1 
ATOM   2349 C CA    . CYS B 2 114 ? 132.667 135.445 106.945 1.00 0.31   ? 103 CYS B CA    1 
ATOM   2350 C C     . CYS B 2 114 ? 131.574 134.795 106.109 1.00 2.11   ? 103 CYS B C     1 
ATOM   2351 O O     . CYS B 2 114 ? 130.392 135.120 106.247 1.00 6.00   ? 103 CYS B O     1 
ATOM   2352 C CB    . CYS B 2 114 ? 132.861 134.685 108.264 1.00 0.00   ? 103 CYS B CB    1 
ATOM   2353 S SG    . CYS B 2 114 ? 131.341 134.230 109.121 1.00 0.00   ? 103 CYS B SG    1 
ATOM   2354 N N     . ALA B 2 115 ? 131.982 133.880 105.235 1.00 7.64   ? 104 ALA B N     1 
ATOM   2355 C CA    . ALA B 2 115 ? 131.066 133.198 104.334 1.00 2.79   ? 104 ALA B CA    1 
ATOM   2356 C C     . ALA B 2 115 ? 131.333 131.703 104.362 1.00 0.00   ? 104 ALA B C     1 
ATOM   2357 O O     . ALA B 2 115 ? 132.479 131.270 104.503 1.00 4.39   ? 104 ALA B O     1 
ATOM   2358 C CB    . ALA B 2 115 ? 131.198 133.718 102.900 1.00 0.00   ? 104 ALA B CB    1 
ATOM   2359 N N     . TYR B 2 116 ? 130.268 130.923 104.221 1.00 3.51   ? 105 TYR B N     1 
ATOM   2360 C CA    . TYR B 2 116 ? 130.343 129.471 104.172 1.00 0.00   ? 105 TYR B CA    1 
ATOM   2361 C C     . TYR B 2 116 ? 129.928 129.023 102.777 1.00 2.80   ? 105 TYR B C     1 
ATOM   2362 O O     . TYR B 2 116 ? 128.855 129.402 102.296 1.00 3.05   ? 105 TYR B O     1 
ATOM   2363 C CB    . TYR B 2 116 ? 129.434 128.848 105.234 1.00 0.00   ? 105 TYR B CB    1 
ATOM   2364 C CG    . TYR B 2 116 ? 129.745 127.407 105.564 1.00 2.50   ? 105 TYR B CG    1 
ATOM   2365 C CD1   . TYR B 2 116 ? 130.590 127.087 106.617 1.00 4.06   ? 105 TYR B CD1   1 
ATOM   2366 C CD2   . TYR B 2 116 ? 129.201 126.368 104.824 1.00 2.41   ? 105 TYR B CD2   1 
ATOM   2367 C CE1   . TYR B 2 116 ? 130.881 125.776 106.929 1.00 2.44   ? 105 TYR B CE1   1 
ATOM   2368 C CE2   . TYR B 2 116 ? 129.488 125.052 105.128 1.00 3.64   ? 105 TYR B CE2   1 
ATOM   2369 C CZ    . TYR B 2 116 ? 130.330 124.762 106.182 1.00 3.29   ? 105 TYR B CZ    1 
ATOM   2370 O OH    . TYR B 2 116 ? 130.621 123.455 106.491 1.00 9.84   ? 105 TYR B OH    1 
ATOM   2371 N N     . ALA B 2 117 ? 130.777 128.233 102.128 1.00 0.00   ? 106 ALA B N     1 
ATOM   2372 C CA    . ALA B 2 117 ? 130.506 127.830 100.756 1.00 0.00   ? 106 ALA B CA    1 
ATOM   2373 C C     . ALA B 2 117 ? 129.282 126.918 100.701 1.00 0.00   ? 106 ALA B C     1 
ATOM   2374 O O     . ALA B 2 117 ? 129.061 126.120 101.616 1.00 0.93   ? 106 ALA B O     1 
ATOM   2375 C CB    . ALA B 2 117 ? 131.715 127.119 100.152 1.00 0.00   ? 106 ALA B CB    1 
ATOM   2376 N N     . PRO B 2 118 ? 128.464 127.023 99.650  1.00 2.85   ? 107 PRO B N     1 
ATOM   2377 C CA    . PRO B 2 118 ? 127.298 126.132 99.541  1.00 1.21   ? 107 PRO B CA    1 
ATOM   2378 C C     . PRO B 2 118 ? 127.667 124.661 99.513  1.00 0.97   ? 107 PRO B C     1 
ATOM   2379 O O     . PRO B 2 118 ? 126.899 123.828 100.007 1.00 2.49   ? 107 PRO B O     1 
ATOM   2380 C CB    . PRO B 2 118 ? 126.641 126.577 98.227  1.00 0.36   ? 107 PRO B CB    1 
ATOM   2381 C CG    . PRO B 2 118 ? 127.109 127.980 98.026  1.00 0.35   ? 107 PRO B CG    1 
ATOM   2382 C CD    . PRO B 2 118 ? 128.504 128.016 98.564  1.00 1.22   ? 107 PRO B CD    1 
ATOM   2383 N N     . SER B 2 119 ? 128.823 124.314 98.944  1.00 2.71   ? 108 SER B N     1 
ATOM   2384 C CA    . SER B 2 119 ? 129.274 122.929 98.958  1.00 1.32   ? 108 SER B CA    1 
ATOM   2385 C C     . SER B 2 119 ? 129.796 122.507 100.324 1.00 2.01   ? 108 SER B C     1 
ATOM   2386 O O     . SER B 2 119 ? 129.839 121.307 100.613 1.00 3.68   ? 108 SER B O     1 
ATOM   2387 C CB    . SER B 2 119 ? 130.361 122.721 97.905  1.00 2.59   ? 108 SER B CB    1 
ATOM   2388 O OG    . SER B 2 119 ? 131.512 123.488 98.211  1.00 2.10   ? 108 SER B OG    1 
ATOM   2389 N N     . GLY B 2 120 ? 130.189 123.460 101.165 1.00 1.76   ? 109 GLY B N     1 
ATOM   2390 C CA    . GLY B 2 120 ? 130.759 123.160 102.458 1.00 0.00   ? 109 GLY B CA    1 
ATOM   2391 C C     . GLY B 2 120 ? 132.238 122.848 102.448 1.00 2.28   ? 109 GLY B C     1 
ATOM   2392 O O     . GLY B 2 120 ? 132.808 122.602 103.518 1.00 5.69   ? 109 GLY B O     1 
ATOM   2393 N N     . ASN B 2 121 ? 132.878 122.849 101.278 1.00 2.16   ? 110 ASN B N     1 
ATOM   2394 C CA    . ASN B 2 121 ? 134.294 122.521 101.186 1.00 1.15   ? 110 ASN B CA    1 
ATOM   2395 C C     . ASN B 2 121 ? 135.196 123.710 101.481 1.00 2.10   ? 110 ASN B C     1 
ATOM   2396 O O     . ASN B 2 121 ? 136.396 123.517 101.703 1.00 3.11   ? 110 ASN B O     1 
ATOM   2397 C CB    . ASN B 2 121 ? 134.614 121.975 99.793  1.00 1.23   ? 110 ASN B CB    1 
ATOM   2398 C CG    . ASN B 2 121 ? 133.743 120.797 99.416  1.00 2.24   ? 110 ASN B CG    1 
ATOM   2399 O OD1   . ASN B 2 121 ? 133.297 120.038 100.276 1.00 4.11   ? 110 ASN B OD1   1 
ATOM   2400 N ND2   . ASN B 2 121 ? 133.489 120.640 98.123  1.00 1.12   ? 110 ASN B ND2   1 
ATOM   2401 N N     . TYR B 2 122 ? 134.654 124.925 101.489 1.00 2.21   ? 111 TYR B N     1 
ATOM   2402 C CA    . TYR B 2 122 ? 135.454 126.125 101.673 1.00 1.49   ? 111 TYR B CA    1 
ATOM   2403 C C     . TYR B 2 122 ? 134.744 127.071 102.628 1.00 0.72   ? 111 TYR B C     1 
ATOM   2404 O O     . TYR B 2 122 ? 133.523 127.025 102.792 1.00 0.26   ? 111 TYR B O     1 
ATOM   2405 C CB    . TYR B 2 122 ? 135.725 126.835 100.340 1.00 1.24   ? 111 TYR B CB    1 
ATOM   2406 C CG    . TYR B 2 122 ? 136.628 126.065 99.406  1.00 1.65   ? 111 TYR B CG    1 
ATOM   2407 C CD1   . TYR B 2 122 ? 138.008 126.174 99.498  1.00 1.02   ? 111 TYR B CD1   1 
ATOM   2408 C CD2   . TYR B 2 122 ? 136.100 125.232 98.429  1.00 0.00   ? 111 TYR B CD2   1 
ATOM   2409 C CE1   . TYR B 2 122 ? 138.837 125.474 98.647  1.00 2.31   ? 111 TYR B CE1   1 
ATOM   2410 C CE2   . TYR B 2 122 ? 136.922 124.528 97.572  1.00 0.12   ? 111 TYR B CE2   1 
ATOM   2411 C CZ    . TYR B 2 122 ? 138.289 124.653 97.685  1.00 4.69   ? 111 TYR B CZ    1 
ATOM   2412 O OH    . TYR B 2 122 ? 139.112 123.953 96.834  1.00 5.38   ? 111 TYR B OH    1 
ATOM   2413 N N     . VAL B 2 123 ? 135.535 127.930 103.267 1.00 0.42   ? 112 VAL B N     1 
ATOM   2414 C CA    . VAL B 2 123 ? 135.014 128.991 104.116 1.00 1.47   ? 112 VAL B CA    1 
ATOM   2415 C C     . VAL B 2 123 ? 135.746 130.275 103.744 1.00 0.00   ? 112 VAL B C     1 
ATOM   2416 O O     . VAL B 2 123 ? 136.857 130.248 103.216 1.00 0.00   ? 112 VAL B O     1 
ATOM   2417 C CB    . VAL B 2 123 ? 135.174 128.665 105.621 1.00 1.33   ? 112 VAL B CB    1 
ATOM   2418 C CG1   . VAL B 2 123 ? 136.639 128.654 106.023 1.00 0.65   ? 112 VAL B CG1   1 
ATOM   2419 C CG2   . VAL B 2 123 ? 134.369 129.619 106.481 1.00 2.87   ? 112 VAL B CG2   1 
ATOM   2420 N N     . ALA B 2 124 ? 135.101 131.409 104.000 1.00 0.00   ? 113 ALA B N     1 
ATOM   2421 C CA    . ALA B 2 124 ? 135.674 132.703 103.662 1.00 0.00   ? 113 ALA B CA    1 
ATOM   2422 C C     . ALA B 2 124 ? 135.645 133.620 104.875 1.00 0.00   ? 113 ALA B C     1 
ATOM   2423 O O     . ALA B 2 124 ? 134.832 133.458 105.787 1.00 5.31   ? 113 ALA B O     1 
ATOM   2424 C CB    . ALA B 2 124 ? 134.935 133.369 102.495 1.00 0.00   ? 113 ALA B CB    1 
ATOM   2425 N N     . CYS B 2 125 ? 136.564 134.581 104.875 1.00 1.94   ? 114 CYS B N     1 
ATOM   2426 C CA    . CYS B 2 125 ? 136.608 135.611 105.904 1.00 1.08   ? 114 CYS B CA    1 
ATOM   2427 C C     . CYS B 2 125 ? 137.336 136.817 105.331 1.00 1.40   ? 114 CYS B C     1 
ATOM   2428 O O     . CYS B 2 125 ? 137.964 136.742 104.275 1.00 1.38   ? 114 CYS B O     1 
ATOM   2429 C CB    . CYS B 2 125 ? 137.285 135.107 107.184 1.00 0.26   ? 114 CYS B CB    1 
ATOM   2430 S SG    . CYS B 2 125 ? 139.090 135.123 107.140 1.00 16.57  ? 114 CYS B SG    1 
ATOM   2431 N N     . GLY B 2 126 ? 137.231 137.936 106.032 1.00 0.38   ? 115 GLY B N     1 
ATOM   2432 C CA    . GLY B 2 126 ? 137.899 139.150 105.599 1.00 0.00   ? 115 GLY B CA    1 
ATOM   2433 C C     . GLY B 2 126 ? 137.552 140.284 106.533 1.00 0.41   ? 115 GLY B C     1 
ATOM   2434 O O     . GLY B 2 126 ? 136.650 140.179 107.367 1.00 0.00   ? 115 GLY B O     1 
ATOM   2435 N N     . GLY B 2 127 ? 138.283 141.384 106.377 1.00 0.00   ? 116 GLY B N     1 
ATOM   2436 C CA    . GLY B 2 127 ? 138.084 142.523 107.250 1.00 0.00   ? 116 GLY B CA    1 
ATOM   2437 C C     . GLY B 2 127 ? 138.961 143.717 106.939 1.00 0.00   ? 116 GLY B C     1 
ATOM   2438 O O     . GLY B 2 127 ? 139.093 144.116 105.779 1.00 0.00   ? 116 GLY B O     1 
ATOM   2439 N N     . LEU B 2 128 ? 139.566 144.297 107.979 1.00 2.23   ? 117 LEU B N     1 
ATOM   2440 C CA    . LEU B 2 128 ? 140.362 145.509 107.832 1.00 1.40   ? 117 LEU B CA    1 
ATOM   2441 C C     . LEU B 2 128 ? 141.649 145.292 107.047 1.00 0.66   ? 117 LEU B C     1 
ATOM   2442 O O     . LEU B 2 128 ? 142.295 146.276 106.674 1.00 2.34   ? 117 LEU B O     1 
ATOM   2443 C CB    . LEU B 2 128 ? 140.694 146.089 109.208 1.00 2.30   ? 117 LEU B CB    1 
ATOM   2444 C CG    . LEU B 2 128 ? 139.509 146.465 110.099 1.00 0.00   ? 117 LEU B CG    1 
ATOM   2445 C CD1   . LEU B 2 128 ? 139.985 147.186 111.350 1.00 0.00   ? 117 LEU B CD1   1 
ATOM   2446 C CD2   . LEU B 2 128 ? 138.518 147.320 109.335 1.00 0.07   ? 117 LEU B CD2   1 
ATOM   2447 N N     . ASP B 2 129 ? 142.037 144.044 106.789 1.00 2.50   ? 118 ASP B N     1 
ATOM   2448 C CA    . ASP B 2 129 ? 143.226 143.771 105.993 1.00 0.27   ? 118 ASP B CA    1 
ATOM   2449 C C     . ASP B 2 129 ? 142.992 143.949 104.499 1.00 1.62   ? 118 ASP B C     1 
ATOM   2450 O O     . ASP B 2 129 ? 143.948 143.832 103.725 1.00 3.44   ? 118 ASP B O     1 
ATOM   2451 C CB    . ASP B 2 129 ? 143.733 142.352 106.267 1.00 0.00   ? 118 ASP B CB    1 
ATOM   2452 C CG    . ASP B 2 129 ? 142.670 141.294 106.038 1.00 1.18   ? 118 ASP B CG    1 
ATOM   2453 O OD1   . ASP B 2 129 ? 141.506 141.658 105.774 1.00 2.31   ? 118 ASP B OD1   1 
ATOM   2454 O OD2   . ASP B 2 129 ? 143.002 140.094 106.121 1.00 3.49   ? 118 ASP B OD2   1 
ATOM   2455 N N     . ASN B 2 130 ? 141.753 144.217 104.084 1.00 1.52   ? 119 ASN B N     1 
ATOM   2456 C CA    . ASN B 2 130 ? 141.375 144.402 102.684 1.00 1.90   ? 119 ASN B CA    1 
ATOM   2457 C C     . ASN B 2 130 ? 141.647 143.162 101.841 1.00 2.13   ? 119 ASN B C     1 
ATOM   2458 O O     . ASN B 2 130 ? 141.863 143.265 100.630 1.00 3.76   ? 119 ASN B O     1 
ATOM   2459 C CB    . ASN B 2 130 ? 142.079 145.617 102.067 1.00 0.00   ? 119 ASN B CB    1 
ATOM   2460 C CG    . ASN B 2 130 ? 141.958 146.859 102.922 1.00 0.48   ? 119 ASN B CG    1 
ATOM   2461 O OD1   . ASN B 2 130 ? 141.185 146.897 103.877 1.00 0.57   ? 119 ASN B OD1   1 
ATOM   2462 N ND2   . ASN B 2 130 ? 142.719 147.889 102.576 1.00 2.91   ? 119 ASN B ND2   1 
ATOM   2463 N N     . ILE B 2 131 ? 141.638 141.985 102.461 1.00 3.47   ? 120 ILE B N     1 
ATOM   2464 C CA    . ILE B 2 131 ? 141.928 140.728 101.784 1.00 1.95   ? 120 ILE B CA    1 
ATOM   2465 C C     . ILE B 2 131 ? 140.858 139.719 102.171 1.00 2.96   ? 120 ILE B C     1 
ATOM   2466 O O     . ILE B 2 131 ? 140.525 139.585 103.353 1.00 5.21   ? 120 ILE B O     1 
ATOM   2467 C CB    . ILE B 2 131 ? 143.330 140.196 102.142 1.00 1.34   ? 120 ILE B CB    1 
ATOM   2468 C CG1   . ILE B 2 131 ? 144.412 141.132 101.602 1.00 0.00   ? 120 ILE B CG1   1 
ATOM   2469 C CG2   . ILE B 2 131 ? 143.528 138.790 101.601 1.00 2.57   ? 120 ILE B CG2   1 
ATOM   2470 C CD1   . ILE B 2 131 ? 145.728 141.022 102.333 1.00 1.13   ? 120 ILE B CD1   1 
ATOM   2471 N N     . CYS B 2 132 ? 140.319 139.016 101.178 1.00 0.00   ? 121 CYS B N     1 
ATOM   2472 C CA    . CYS B 2 132 ? 139.363 137.941 101.419 1.00 0.07   ? 121 CYS B CA    1 
ATOM   2473 C C     . CYS B 2 132 ? 140.128 136.624 101.469 1.00 0.45   ? 121 CYS B C     1 
ATOM   2474 O O     . CYS B 2 132 ? 140.632 136.150 100.448 1.00 1.47   ? 121 CYS B O     1 
ATOM   2475 C CB    . CYS B 2 132 ? 138.288 137.914 100.336 1.00 0.60   ? 121 CYS B CB    1 
ATOM   2476 S SG    . CYS B 2 132 ? 136.923 136.776 100.672 1.00 0.00   ? 121 CYS B SG    1 
ATOM   2477 N N     . SER B 2 133 ? 140.225 136.041 102.658 1.00 3.52   ? 122 SER B N     1 
ATOM   2478 C CA    . SER B 2 133 ? 140.924 134.779 102.844 1.00 0.70   ? 122 SER B CA    1 
ATOM   2479 C C     . SER B 2 133 ? 139.933 133.629 102.733 1.00 0.59   ? 122 SER B C     1 
ATOM   2480 O O     . SER B 2 133 ? 138.895 133.624 103.404 1.00 2.03   ? 122 SER B O     1 
ATOM   2481 C CB    . SER B 2 133 ? 141.632 134.746 104.198 1.00 0.99   ? 122 SER B CB    1 
ATOM   2482 O OG    . SER B 2 133 ? 142.563 135.806 104.307 1.00 5.40   ? 122 SER B OG    1 
ATOM   2483 N N     . ILE B 2 134 ? 140.259 132.659 101.885 1.00 3.16   ? 123 ILE B N     1 
ATOM   2484 C CA    . ILE B 2 134 ? 139.423 131.494 101.636 1.00 1.54   ? 123 ILE B CA    1 
ATOM   2485 C C     . ILE B 2 134 ? 140.197 130.265 102.084 1.00 0.00   ? 123 ILE B C     1 
ATOM   2486 O O     . ILE B 2 134 ? 141.298 130.000 101.584 1.00 1.63   ? 123 ILE B O     1 
ATOM   2487 C CB    . ILE B 2 134 ? 139.018 131.391 100.158 1.00 0.01   ? 123 ILE B CB    1 
ATOM   2488 C CG1   . ILE B 2 134 ? 138.300 132.673 99.733  1.00 1.41   ? 123 ILE B CG1   1 
ATOM   2489 C CG2   . ILE B 2 134 ? 138.148 130.165 99.925  1.00 0.04   ? 123 ILE B CG2   1 
ATOM   2490 C CD1   . ILE B 2 134 ? 137.640 132.591 98.392  1.00 2.50   ? 123 ILE B CD1   1 
ATOM   2491 N N     . TYR B 2 135 ? 139.615 129.520 103.019 1.00 0.00   ? 124 TYR B N     1 
ATOM   2492 C CA    . TYR B 2 135 ? 140.238 128.368 103.652 1.00 0.17   ? 124 TYR B CA    1 
ATOM   2493 C C     . TYR B 2 135 ? 139.555 127.095 103.177 1.00 1.64   ? 124 TYR B C     1 
ATOM   2494 O O     . TYR B 2 135 ? 138.321 127.030 103.121 1.00 2.96   ? 124 TYR B O     1 
ATOM   2495 C CB    . TYR B 2 135 ? 140.146 128.467 105.177 1.00 0.00   ? 124 TYR B CB    1 
ATOM   2496 C CG    . TYR B 2 135 ? 140.741 129.726 105.763 1.00 0.91   ? 124 TYR B CG    1 
ATOM   2497 C CD1   . TYR B 2 135 ? 140.003 130.900 105.832 1.00 0.55   ? 124 TYR B CD1   1 
ATOM   2498 C CD2   . TYR B 2 135 ? 142.035 129.736 106.261 1.00 3.65   ? 124 TYR B CD2   1 
ATOM   2499 C CE1   . TYR B 2 135 ? 140.543 132.051 106.369 1.00 2.00   ? 124 TYR B CE1   1 
ATOM   2500 C CE2   . TYR B 2 135 ? 142.583 130.882 106.800 1.00 4.01   ? 124 TYR B CE2   1 
ATOM   2501 C CZ    . TYR B 2 135 ? 141.834 132.036 106.852 1.00 5.63   ? 124 TYR B CZ    1 
ATOM   2502 O OH    . TYR B 2 135 ? 142.379 133.178 107.390 1.00 5.63   ? 124 TYR B OH    1 
ATOM   2503 N N     . ASN B 2 136 ? 140.359 126.089 102.843 1.00 2.10   ? 125 ASN B N     1 
ATOM   2504 C CA    . ASN B 2 136 ? 139.855 124.784 102.442 1.00 1.65   ? 125 ASN B CA    1 
ATOM   2505 C C     . ASN B 2 136 ? 139.604 123.932 103.680 1.00 0.61   ? 125 ASN B C     1 
ATOM   2506 O O     . ASN B 2 136 ? 140.496 123.765 104.518 1.00 2.32   ? 125 ASN B O     1 
ATOM   2507 C CB    . ASN B 2 136 ? 140.848 124.089 101.511 1.00 3.21   ? 125 ASN B CB    1 
ATOM   2508 C CG    . ASN B 2 136 ? 140.246 122.896 100.798 1.00 5.16   ? 125 ASN B CG    1 
ATOM   2509 O OD1   . ASN B 2 136 ? 139.051 122.627 100.912 1.00 5.13   ? 125 ASN B OD1   1 
ATOM   2510 N ND2   . ASN B 2 136 ? 141.074 122.172 100.056 1.00 2.17   ? 125 ASN B ND2   1 
ATOM   2511 N N     . LEU B 2 137 ? 138.390 123.397 103.791 1.00 0.00   ? 126 LEU B N     1 
ATOM   2512 C CA    . LEU B 2 137 ? 138.018 122.577 104.935 1.00 0.12   ? 126 LEU B CA    1 
ATOM   2513 C C     . LEU B 2 137 ? 138.217 121.088 104.696 1.00 4.34   ? 126 LEU B C     1 
ATOM   2514 O O     . LEU B 2 137 ? 138.247 120.319 105.663 1.00 7.34   ? 126 LEU B O     1 
ATOM   2515 C CB    . LEU B 2 137 ? 136.556 122.830 105.313 1.00 2.86   ? 126 LEU B CB    1 
ATOM   2516 C CG    . LEU B 2 137 ? 136.141 124.294 105.450 1.00 1.06   ? 126 LEU B CG    1 
ATOM   2517 C CD1   . LEU B 2 137 ? 134.658 124.400 105.754 1.00 0.00   ? 126 LEU B CD1   1 
ATOM   2518 C CD2   . LEU B 2 137 ? 136.967 124.980 106.523 1.00 0.79   ? 126 LEU B CD2   1 
ATOM   2519 N N     . LYS B 2 138 ? 138.355 120.667 103.442 1.00 2.57   ? 127 LYS B N     1 
ATOM   2520 C CA    . LYS B 2 138 ? 138.465 119.259 103.079 1.00 2.30   ? 127 LYS B CA    1 
ATOM   2521 C C     . LYS B 2 138 ? 139.868 118.915 102.590 1.00 4.31   ? 127 LYS B C     1 
ATOM   2522 O O     . LYS B 2 138 ? 140.043 118.161 101.632 1.00 4.77   ? 127 LYS B O     1 
ATOM   2523 C CB    . LYS B 2 138 ? 137.425 118.893 102.024 1.00 2.20   ? 127 LYS B CB    1 
ATOM   2524 C CG    . LYS B 2 138 ? 136.043 119.461 102.296 1.00 1.79   ? 127 LYS B CG    1 
ATOM   2525 C CD    . LYS B 2 138 ? 135.451 118.889 103.571 1.00 1.32   ? 127 LYS B CD    1 
ATOM   2526 C CE    . LYS B 2 138 ? 134.033 119.384 103.791 1.00 3.51   ? 127 LYS B CE    1 
ATOM   2527 N NZ    . LYS B 2 138 ? 133.095 118.857 102.764 1.00 1.84   ? 127 LYS B NZ    1 
ATOM   2528 N N     . THR B 2 139 ? 140.883 119.473 103.243 1.00 5.52   ? 128 THR B N     1 
ATOM   2529 C CA    . THR B 2 139 ? 142.261 119.181 102.880 1.00 5.80   ? 128 THR B CA    1 
ATOM   2530 C C     . THR B 2 139 ? 142.614 117.734 103.211 1.00 5.84   ? 128 THR B C     1 
ATOM   2531 O O     . THR B 2 139 ? 142.116 117.153 104.179 1.00 5.50   ? 128 THR B O     1 
ATOM   2532 C CB    . THR B 2 139 ? 143.219 120.127 103.604 1.00 6.98   ? 128 THR B CB    1 
ATOM   2533 O OG1   . THR B 2 139 ? 143.292 119.768 104.989 1.00 8.27   ? 128 THR B OG1   1 
ATOM   2534 C CG2   . THR B 2 139 ? 142.741 121.564 103.483 1.00 4.53   ? 128 THR B CG2   1 
ATOM   2535 N N     . ARG B 2 140 ? 143.484 117.151 102.382 1.00 9.67   ? 129 ARG B N     1 
ATOM   2536 C CA    . ARG B 2 140 ? 143.922 115.777 102.605 1.00 7.94   ? 129 ARG B CA    1 
ATOM   2537 C C     . ARG B 2 140 ? 144.718 115.643 103.898 1.00 7.22   ? 129 ARG B C     1 
ATOM   2538 O O     . ARG B 2 140 ? 144.619 114.618 104.582 1.00 4.81   ? 129 ARG B O     1 
ATOM   2539 C CB    . ARG B 2 140 ? 144.751 115.295 101.414 1.00 8.05   ? 129 ARG B CB    1 
ATOM   2540 C CG    . ARG B 2 140 ? 145.285 113.879 101.547 1.00 10.41  ? 129 ARG B CG    1 
ATOM   2541 C CD    . ARG B 2 140 ? 144.167 112.851 101.475 1.00 10.00  ? 129 ARG B CD    1 
ATOM   2542 N NE    . ARG B 2 140 ? 144.655 111.499 101.715 1.00 10.29  ? 129 ARG B NE    1 
ATOM   2543 C CZ    . ARG B 2 140 ? 145.135 110.697 100.773 1.00 13.94  ? 129 ARG B CZ    1 
ATOM   2544 N NH1   . ARG B 2 140 ? 145.202 111.080 99.509  1.00 13.68  ? 129 ARG B NH1   1 
ATOM   2545 N NH2   . ARG B 2 140 ? 145.559 109.483 101.109 1.00 13.38  ? 129 ARG B NH2   1 
ATOM   2546 N N     . GLU B 2 141 ? 145.504 116.662 104.250 1.00 10.09  ? 130 GLU B N     1 
ATOM   2547 C CA    . GLU B 2 141 ? 146.278 116.636 105.486 1.00 7.84   ? 130 GLU B CA    1 
ATOM   2548 C C     . GLU B 2 141 ? 145.406 116.673 106.733 1.00 5.65   ? 130 GLU B C     1 
ATOM   2549 O O     . GLU B 2 141 ? 145.907 116.388 107.825 1.00 7.43   ? 130 GLU B O     1 
ATOM   2550 C CB    . GLU B 2 141 ? 147.264 117.805 105.511 1.00 7.23   ? 130 GLU B CB    1 
ATOM   2551 N N     . GLY B 2 142 ? 144.126 117.024 106.604 1.00 7.30   ? 131 GLY B N     1 
ATOM   2552 C CA    . GLY B 2 142 ? 143.203 117.001 107.715 1.00 7.54   ? 131 GLY B CA    1 
ATOM   2553 C C     . GLY B 2 142 ? 143.105 118.284 108.509 1.00 8.86   ? 131 GLY B C     1 
ATOM   2554 O O     . GLY B 2 142 ? 142.250 118.377 109.399 1.00 10.15  ? 131 GLY B O     1 
ATOM   2555 N N     . ASN B 2 143 ? 143.948 119.270 108.225 1.00 7.41   ? 132 ASN B N     1 
ATOM   2556 C CA    . ASN B 2 143 ? 143.880 120.570 108.870 1.00 6.14   ? 132 ASN B CA    1 
ATOM   2557 C C     . ASN B 2 143 ? 143.340 121.601 107.889 1.00 7.59   ? 132 ASN B C     1 
ATOM   2558 O O     . ASN B 2 143 ? 143.516 121.477 106.674 1.00 9.99   ? 132 ASN B O     1 
ATOM   2559 C CB    . ASN B 2 143 ? 145.255 121.007 109.386 1.00 5.95   ? 132 ASN B CB    1 
ATOM   2560 C CG    . ASN B 2 143 ? 146.332 120.941 108.317 1.00 10.70  ? 132 ASN B CG    1 
ATOM   2561 O OD1   . ASN B 2 143 ? 146.089 120.487 107.200 1.00 11.36  ? 132 ASN B OD1   1 
ATOM   2562 N ND2   . ASN B 2 143 ? 147.531 121.395 108.659 1.00 10.99  ? 132 ASN B ND2   1 
ATOM   2563 N N     . VAL B 2 144 ? 142.672 122.617 108.424 1.00 8.08   ? 133 VAL B N     1 
ATOM   2564 C CA    . VAL B 2 144 ? 142.145 123.694 107.594 1.00 4.92   ? 133 VAL B CA    1 
ATOM   2565 C C     . VAL B 2 144 ? 143.289 124.638 107.250 1.00 5.86   ? 133 VAL B C     1 
ATOM   2566 O O     . VAL B 2 144 ? 143.895 125.247 108.137 1.00 5.96   ? 133 VAL B O     1 
ATOM   2567 C CB    . VAL B 2 144 ? 141.006 124.438 108.303 1.00 3.12   ? 133 VAL B CB    1 
ATOM   2568 C CG1   . VAL B 2 144 ? 140.584 125.647 107.487 1.00 2.91   ? 133 VAL B CG1   1 
ATOM   2569 C CG2   . VAL B 2 144 ? 139.828 123.508 108.529 1.00 3.82   ? 133 VAL B CG2   1 
ATOM   2570 N N     . ARG B 2 145 ? 143.586 124.759 105.961 1.00 5.06   ? 134 ARG B N     1 
ATOM   2571 C CA    . ARG B 2 145 ? 144.643 125.629 105.473 1.00 4.10   ? 134 ARG B CA    1 
ATOM   2572 C C     . ARG B 2 145 ? 144.038 126.710 104.591 1.00 5.27   ? 134 ARG B C     1 
ATOM   2573 O O     . ARG B 2 145 ? 142.984 126.516 103.978 1.00 6.24   ? 134 ARG B O     1 
ATOM   2574 C CB    . ARG B 2 145 ? 145.701 124.841 104.686 1.00 4.42   ? 134 ARG B CB    1 
ATOM   2575 C CG    . ARG B 2 145 ? 145.318 124.556 103.241 1.00 6.43   ? 134 ARG B CG    1 
ATOM   2576 C CD    . ARG B 2 145 ? 146.337 123.667 102.551 1.00 6.26   ? 134 ARG B CD    1 
ATOM   2577 N NE    . ARG B 2 145 ? 146.221 122.276 102.971 1.00 11.60  ? 134 ARG B NE    1 
ATOM   2578 C CZ    . ARG B 2 145 ? 147.015 121.299 102.554 1.00 11.51  ? 134 ARG B CZ    1 
ATOM   2579 N NH1   . ARG B 2 145 ? 147.999 121.524 101.701 1.00 9.74   ? 134 ARG B NH1   1 
ATOM   2580 N NH2   . ARG B 2 145 ? 146.814 120.063 103.005 1.00 9.65   ? 134 ARG B NH2   1 
ATOM   2581 N N     . VAL B 2 146 ? 144.705 127.861 104.543 1.00 5.84   ? 135 VAL B N     1 
ATOM   2582 C CA    . VAL B 2 146 ? 144.256 128.934 103.665 1.00 3.59   ? 135 VAL B CA    1 
ATOM   2583 C C     . VAL B 2 146 ? 144.533 128.532 102.222 1.00 3.69   ? 135 VAL B C     1 
ATOM   2584 O O     . VAL B 2 146 ? 145.668 128.204 101.854 1.00 6.74   ? 135 VAL B O     1 
ATOM   2585 C CB    . VAL B 2 146 ? 144.922 130.268 104.034 1.00 4.38   ? 135 VAL B CB    1 
ATOM   2586 C CG1   . VAL B 2 146 ? 146.442 130.162 103.999 1.00 8.35   ? 135 VAL B CG1   1 
ATOM   2587 C CG2   . VAL B 2 146 ? 144.438 131.375 103.110 1.00 2.57   ? 135 VAL B CG2   1 
ATOM   2588 N N     . SER B 2 147 ? 143.485 128.517 101.403 1.00 1.54   ? 136 SER B N     1 
ATOM   2589 C CA    . SER B 2 147 ? 143.623 128.116 100.011 1.00 1.71   ? 136 SER B CA    1 
ATOM   2590 C C     . SER B 2 147 ? 143.794 129.302 99.077  1.00 4.82   ? 136 SER B C     1 
ATOM   2591 O O     . SER B 2 147 ? 144.417 129.162 98.018  1.00 6.66   ? 136 SER B O     1 
ATOM   2592 C CB    . SER B 2 147 ? 142.409 127.292 99.575  1.00 2.09   ? 136 SER B CB    1 
ATOM   2593 O OG    . SER B 2 147 ? 141.380 128.126 99.072  1.00 4.65   ? 136 SER B OG    1 
ATOM   2594 N N     . ARG B 2 148 ? 143.262 130.466 99.443  1.00 5.20   ? 137 ARG B N     1 
ATOM   2595 C CA    . ARG B 2 148 ? 143.367 131.637 98.587  1.00 1.17   ? 137 ARG B CA    1 
ATOM   2596 C C     . ARG B 2 148 ? 143.359 132.894 99.444  1.00 0.38   ? 137 ARG B C     1 
ATOM   2597 O O     . ARG B 2 148 ? 142.777 132.918 100.529 1.00 1.09   ? 137 ARG B O     1 
ATOM   2598 C CB    . ARG B 2 148 ? 142.226 131.679 97.563  1.00 3.75   ? 137 ARG B CB    1 
ATOM   2599 C CG    . ARG B 2 148 ? 142.418 132.691 96.447  1.00 2.91   ? 137 ARG B CG    1 
ATOM   2600 C CD    . ARG B 2 148 ? 143.683 132.409 95.657  1.00 4.36   ? 137 ARG B CD    1 
ATOM   2601 N NE    . ARG B 2 148 ? 143.648 131.096 95.025  1.00 8.55   ? 137 ARG B NE    1 
ATOM   2602 C CZ    . ARG B 2 148 ? 144.722 130.428 94.630  1.00 8.37   ? 137 ARG B CZ    1 
ATOM   2603 N NH1   . ARG B 2 148 ? 145.938 130.924 94.779  1.00 8.57   ? 137 ARG B NH1   1 
ATOM   2604 N NH2   . ARG B 2 148 ? 144.571 129.231 94.070  1.00 4.75   ? 137 ARG B NH2   1 
ATOM   2605 N N     . GLU B 2 149 ? 144.014 133.940 98.943  1.00 4.66   ? 138 GLU B N     1 
ATOM   2606 C CA    . GLU B 2 149 ? 144.013 135.262 99.571  1.00 1.65   ? 138 GLU B CA    1 
ATOM   2607 C C     . GLU B 2 149 ? 143.727 136.278 98.471  1.00 3.79   ? 138 GLU B C     1 
ATOM   2608 O O     . GLU B 2 149 ? 144.648 136.796 97.835  1.00 6.40   ? 138 GLU B O     1 
ATOM   2609 C CB    . GLU B 2 149 ? 145.333 135.544 100.279 1.00 0.46   ? 138 GLU B CB    1 
ATOM   2610 C CG    . GLU B 2 149 ? 145.536 134.737 101.549 1.00 4.03   ? 138 GLU B CG    1 
ATOM   2611 C CD    . GLU B 2 149 ? 146.338 135.485 102.593 1.00 8.53   ? 138 GLU B CD    1 
ATOM   2612 O OE1   . GLU B 2 149 ? 147.462 135.928 102.277 1.00 6.70   ? 138 GLU B OE1   1 
ATOM   2613 O OE2   . GLU B 2 149 ? 145.844 135.631 103.730 1.00 6.94   ? 138 GLU B OE2   1 
ATOM   2614 N N     . LEU B 2 150 ? 142.445 136.557 98.248  1.00 2.92   ? 139 LEU B N     1 
ATOM   2615 C CA    . LEU B 2 150 ? 142.019 137.491 97.213  1.00 2.13   ? 139 LEU B CA    1 
ATOM   2616 C C     . LEU B 2 150 ? 142.317 138.911 97.676  1.00 2.11   ? 139 LEU B C     1 
ATOM   2617 O O     . LEU B 2 150 ? 141.763 139.375 98.678  1.00 4.93   ? 139 LEU B O     1 
ATOM   2618 C CB    . LEU B 2 150 ? 140.534 137.308 96.919  1.00 3.86   ? 139 LEU B CB    1 
ATOM   2619 C CG    . LEU B 2 150 ? 140.090 135.891 96.559  1.00 2.31   ? 139 LEU B CG    1 
ATOM   2620 C CD1   . LEU B 2 150 ? 138.586 135.760 96.688  1.00 0.00   ? 139 LEU B CD1   1 
ATOM   2621 C CD2   . LEU B 2 150 ? 140.540 135.533 95.154  1.00 5.90   ? 139 LEU B CD2   1 
ATOM   2622 N N     . ALA B 2 151 ? 143.189 139.599 96.947  1.00 1.79   ? 140 ALA B N     1 
ATOM   2623 C CA    . ALA B 2 151 ? 143.581 140.963 97.260  1.00 1.64   ? 140 ALA B CA    1 
ATOM   2624 C C     . ALA B 2 151 ? 143.320 141.860 96.059  1.00 6.04   ? 140 ALA B C     1 
ATOM   2625 O O     . ALA B 2 151 ? 143.299 141.402 94.913  1.00 6.81   ? 140 ALA B O     1 
ATOM   2626 C CB    . ALA B 2 151 ? 145.058 141.040 97.661  1.00 0.44   ? 140 ALA B CB    1 
ATOM   2627 N N     . GLY B 2 152 ? 143.133 143.147 96.331  1.00 4.46   ? 141 GLY B N     1 
ATOM   2628 C CA    . GLY B 2 152 ? 142.813 144.104 95.291  1.00 2.35   ? 141 GLY B CA    1 
ATOM   2629 C C     . GLY B 2 152 ? 141.834 145.161 95.754  1.00 4.67   ? 141 GLY B C     1 
ATOM   2630 O O     . GLY B 2 152 ? 141.815 146.274 95.219  1.00 11.01  ? 141 GLY B O     1 
ATOM   2631 N N     . HIS B 2 153 ? 141.016 144.826 96.747  1.00 2.01   ? 142 HIS B N     1 
ATOM   2632 C CA    . HIS B 2 153 ? 140.163 145.824 97.376  1.00 0.91   ? 142 HIS B CA    1 
ATOM   2633 C C     . HIS B 2 153 ? 141.013 146.787 98.195  1.00 3.81   ? 142 HIS B C     1 
ATOM   2634 O O     . HIS B 2 153 ? 141.907 146.373 98.937  1.00 7.93   ? 142 HIS B O     1 
ATOM   2635 C CB    . HIS B 2 153 ? 139.122 145.153 98.271  1.00 2.36   ? 142 HIS B CB    1 
ATOM   2636 C CG    . HIS B 2 153 ? 137.879 144.732 97.551  1.00 4.68   ? 142 HIS B CG    1 
ATOM   2637 N ND1   . HIS B 2 153 ? 137.200 145.563 96.686  1.00 7.37   ? 142 HIS B ND1   1 
ATOM   2638 C CD2   . HIS B 2 153 ? 137.181 143.572 97.583  1.00 0.70   ? 142 HIS B CD2   1 
ATOM   2639 C CE1   . HIS B 2 153 ? 136.144 144.931 96.209  1.00 2.86   ? 142 HIS B CE1   1 
ATOM   2640 N NE2   . HIS B 2 153 ? 136.109 143.721 96.737  1.00 0.60   ? 142 HIS B NE2   1 
ATOM   2641 N N     . THR B 2 154 ? 140.734 148.081 98.056  1.00 1.83   ? 143 THR B N     1 
ATOM   2642 C CA    . THR B 2 154 ? 141.464 149.111 98.780  1.00 1.14   ? 143 THR B CA    1 
ATOM   2643 C C     . THR B 2 154 ? 140.747 149.552 100.049 1.00 2.75   ? 143 THR B C     1 
ATOM   2644 O O     . THR B 2 154 ? 141.187 150.503 100.702 1.00 5.02   ? 143 THR B O     1 
ATOM   2645 C CB    . THR B 2 154 ? 141.723 150.316 97.874  1.00 2.77   ? 143 THR B CB    1 
ATOM   2646 O OG1   . THR B 2 154 ? 140.477 150.892 97.468  1.00 2.74   ? 143 THR B OG1   1 
ATOM   2647 C CG2   . THR B 2 154 ? 142.503 149.892 96.640  1.00 2.65   ? 143 THR B CG2   1 
ATOM   2648 N N     . GLY B 2 155 ? 139.650 148.881 100.413 1.00 0.00   ? 144 GLY B N     1 
ATOM   2649 C CA    . GLY B 2 155 ? 138.950 149.171 101.642 1.00 0.00   ? 144 GLY B CA    1 
ATOM   2650 C C     . GLY B 2 155 ? 138.686 147.894 102.420 1.00 2.52   ? 144 GLY B C     1 
ATOM   2651 O O     . GLY B 2 155 ? 138.944 146.787 101.945 1.00 2.26   ? 144 GLY B O     1 
ATOM   2652 N N     . TYR B 2 156 ? 138.164 148.072 103.631 1.00 0.00   ? 145 TYR B N     1 
ATOM   2653 C CA    . TYR B 2 156 ? 137.885 146.934 104.495 1.00 0.54   ? 145 TYR B CA    1 
ATOM   2654 C C     . TYR B 2 156 ? 136.808 146.046 103.886 1.00 3.25   ? 145 TYR B C     1 
ATOM   2655 O O     . TYR B 2 156 ? 135.839 146.530 103.296 1.00 2.99   ? 145 TYR B O     1 
ATOM   2656 C CB    . TYR B 2 156 ? 137.449 147.414 105.881 1.00 0.34   ? 145 TYR B CB    1 
ATOM   2657 C CG    . TYR B 2 156 ? 136.205 148.274 105.875 1.00 0.00   ? 145 TYR B CG    1 
ATOM   2658 C CD1   . TYR B 2 156 ? 136.288 149.646 105.678 1.00 1.13   ? 145 TYR B CD1   1 
ATOM   2659 C CD2   . TYR B 2 156 ? 134.949 147.716 106.073 1.00 1.79   ? 145 TYR B CD2   1 
ATOM   2660 C CE1   . TYR B 2 156 ? 135.156 150.435 105.672 1.00 3.02   ? 145 TYR B CE1   1 
ATOM   2661 C CE2   . TYR B 2 156 ? 133.812 148.498 106.068 1.00 1.56   ? 145 TYR B CE2   1 
ATOM   2662 C CZ    . TYR B 2 156 ? 133.922 149.857 105.867 1.00 1.83   ? 145 TYR B CZ    1 
ATOM   2663 O OH    . TYR B 2 156 ? 132.794 150.642 105.861 1.00 5.19   ? 145 TYR B OH    1 
ATOM   2664 N N     . LEU B 2 157 ? 136.984 144.736 104.033 1.00 0.07   ? 146 LEU B N     1 
ATOM   2665 C CA    . LEU B 2 157 ? 136.010 143.770 103.542 1.00 3.41   ? 146 LEU B CA    1 
ATOM   2666 C C     . LEU B 2 157 ? 134.817 143.733 104.488 1.00 3.30   ? 146 LEU B C     1 
ATOM   2667 O O     . LEU B 2 157 ? 134.958 143.366 105.659 1.00 4.05   ? 146 LEU B O     1 
ATOM   2668 C CB    . LEU B 2 157 ? 136.647 142.388 103.419 1.00 2.29   ? 146 LEU B CB    1 
ATOM   2669 C CG    . LEU B 2 157 ? 137.198 141.989 102.050 1.00 0.55   ? 146 LEU B CG    1 
ATOM   2670 C CD1   . LEU B 2 157 ? 136.062 141.806 101.072 1.00 0.27   ? 146 LEU B CD1   1 
ATOM   2671 C CD2   . LEU B 2 157 ? 138.178 143.022 101.529 1.00 1.74   ? 146 LEU B CD2   1 
ATOM   2672 N N     . SER B 2 158 ? 133.643 144.109 103.984 1.00 0.00   ? 147 SER B N     1 
ATOM   2673 C CA    . SER B 2 158 ? 132.444 144.180 104.809 1.00 0.00   ? 147 SER B CA    1 
ATOM   2674 C C     . SER B 2 158 ? 131.529 142.977 104.647 1.00 0.97   ? 147 SER B C     1 
ATOM   2675 O O     . SER B 2 158 ? 130.872 142.581 105.615 1.00 0.00   ? 147 SER B O     1 
ATOM   2676 C CB    . SER B 2 158 ? 131.659 145.457 104.493 1.00 0.00   ? 147 SER B CB    1 
ATOM   2677 O OG    . SER B 2 158 ? 131.235 145.475 103.142 1.00 0.00   ? 147 SER B OG    1 
ATOM   2678 N N     . CYS B 2 159 ? 131.467 142.388 103.456 1.00 0.00   ? 148 CYS B N     1 
ATOM   2679 C CA    . CYS B 2 159 ? 130.662 141.197 103.239 1.00 0.00   ? 148 CYS B CA    1 
ATOM   2680 C C     . CYS B 2 159 ? 131.288 140.364 102.132 1.00 0.00   ? 148 CYS B C     1 
ATOM   2681 O O     . CYS B 2 159 ? 131.995 140.885 101.266 1.00 0.00   ? 148 CYS B O     1 
ATOM   2682 C CB    . CYS B 2 159 ? 129.211 141.546 102.887 1.00 0.00   ? 148 CYS B CB    1 
ATOM   2683 S SG    . CYS B 2 159 ? 128.046 140.180 103.097 1.00 0.00   ? 148 CYS B SG    1 
ATOM   2684 N N     . CYS B 2 160 ? 131.028 139.061 102.180 1.00 6.94   ? 149 CYS B N     1 
ATOM   2685 C CA    . CYS B 2 160 ? 131.466 138.136 101.146 1.00 1.42   ? 149 CYS B CA    1 
ATOM   2686 C C     . CYS B 2 160 ? 130.476 136.984 101.089 1.00 4.28   ? 149 CYS B C     1 
ATOM   2687 O O     . CYS B 2 160 ? 129.969 136.546 102.124 1.00 5.77   ? 149 CYS B O     1 
ATOM   2688 C CB    . CYS B 2 160 ? 132.884 137.615 101.410 1.00 0.31   ? 149 CYS B CB    1 
ATOM   2689 S SG    . CYS B 2 160 ? 133.120 136.828 103.020 1.00 4.39   ? 149 CYS B SG    1 
ATOM   2690 N N     . ARG B 2 161 ? 130.196 136.506 99.878  1.00 0.00   ? 150 ARG B N     1 
ATOM   2691 C CA    . ARG B 2 161 ? 129.232 135.430 99.687  1.00 0.13   ? 150 ARG B CA    1 
ATOM   2692 C C     . ARG B 2 161 ? 129.682 134.546 98.536  1.00 0.00   ? 150 ARG B C     1 
ATOM   2693 O O     . ARG B 2 161 ? 129.915 135.038 97.429  1.00 0.00   ? 150 ARG B O     1 
ATOM   2694 C CB    . ARG B 2 161 ? 127.829 135.983 99.411  1.00 0.84   ? 150 ARG B CB    1 
ATOM   2695 C CG    . ARG B 2 161 ? 127.096 136.475 100.645 1.00 0.00   ? 150 ARG B CG    1 
ATOM   2696 C CD    . ARG B 2 161 ? 126.874 135.345 101.633 1.00 2.38   ? 150 ARG B CD    1 
ATOM   2697 N NE    . ARG B 2 161 ? 126.264 135.812 102.872 1.00 0.00   ? 150 ARG B NE    1 
ATOM   2698 C CZ    . ARG B 2 161 ? 126.912 135.947 104.020 1.00 0.00   ? 150 ARG B CZ    1 
ATOM   2699 N NH1   . ARG B 2 161 ? 128.200 135.664 104.124 1.00 2.05   ? 150 ARG B NH1   1 
ATOM   2700 N NH2   . ARG B 2 161 ? 126.252 136.376 105.091 1.00 0.90   ? 150 ARG B NH2   1 
ATOM   2701 N N     . PHE B 2 162 ? 129.797 133.248 98.801  1.00 3.87   ? 151 PHE B N     1 
ATOM   2702 C CA    . PHE B 2 162 ? 130.158 132.298 97.758  1.00 0.40   ? 151 PHE B CA    1 
ATOM   2703 C C     . PHE B 2 162 ? 129.019 132.122 96.762  1.00 3.14   ? 151 PHE B C     1 
ATOM   2704 O O     . PHE B 2 162 ? 127.846 132.046 97.139  1.00 8.03   ? 151 PHE B O     1 
ATOM   2705 C CB    . PHE B 2 162 ? 130.506 130.939 98.362  1.00 0.00   ? 151 PHE B CB    1 
ATOM   2706 C CG    . PHE B 2 162 ? 131.897 130.845 98.912  1.00 0.37   ? 151 PHE B CG    1 
ATOM   2707 C CD1   . PHE B 2 162 ? 132.973 130.626 98.070  1.00 0.00   ? 151 PHE B CD1   1 
ATOM   2708 C CD2   . PHE B 2 162 ? 132.126 130.937 100.272 1.00 0.00   ? 151 PHE B CD2   1 
ATOM   2709 C CE1   . PHE B 2 162 ? 134.253 130.525 98.572  1.00 0.00   ? 151 PHE B CE1   1 
ATOM   2710 C CE2   . PHE B 2 162 ? 133.401 130.831 100.779 1.00 0.00   ? 151 PHE B CE2   1 
ATOM   2711 C CZ    . PHE B 2 162 ? 134.467 130.627 99.929  1.00 0.00   ? 151 PHE B CZ    1 
ATOM   2712 N N     . LEU B 2 163 ? 129.374 132.051 95.482  1.00 4.49   ? 152 LEU B N     1 
ATOM   2713 C CA    . LEU B 2 163 ? 128.455 131.575 94.456  1.00 4.20   ? 152 LEU B CA    1 
ATOM   2714 C C     . LEU B 2 163 ? 128.675 130.098 94.168  1.00 5.32   ? 152 LEU B C     1 
ATOM   2715 O O     . LEU B 2 163 ? 127.711 129.344 93.998  1.00 7.67   ? 152 LEU B O     1 
ATOM   2716 C CB    . LEU B 2 163 ? 128.623 132.384 93.168  1.00 2.54   ? 152 LEU B CB    1 
ATOM   2717 C CG    . LEU B 2 163 ? 127.970 133.763 93.110  1.00 4.08   ? 152 LEU B CG    1 
ATOM   2718 C CD1   . LEU B 2 163 ? 128.838 134.784 93.813  1.00 1.98   ? 152 LEU B CD1   1 
ATOM   2719 C CD2   . LEU B 2 163 ? 127.722 134.169 91.670  1.00 6.09   ? 152 LEU B CD2   1 
ATOM   2720 N N     . ASP B 2 164 ? 129.933 129.682 94.117  1.00 2.04   ? 153 ASP B N     1 
ATOM   2721 C CA    . ASP B 2 164 ? 130.319 128.293 93.927  1.00 2.46   ? 153 ASP B CA    1 
ATOM   2722 C C     . ASP B 2 164 ? 131.641 128.087 94.658  1.00 7.46   ? 153 ASP B C     1 
ATOM   2723 O O     . ASP B 2 164 ? 132.031 128.903 95.500  1.00 8.45   ? 153 ASP B O     1 
ATOM   2724 C CB    . ASP B 2 164 ? 130.394 127.956 92.427  1.00 3.09   ? 153 ASP B CB    1 
ATOM   2725 N N     . ASP B 2 165 ? 132.335 126.995 94.344  1.00 6.52   ? 154 ASP B N     1 
ATOM   2726 C CA    . ASP B 2 165 ? 133.647 126.750 94.928  1.00 1.26   ? 154 ASP B CA    1 
ATOM   2727 C C     . ASP B 2 165 ? 134.754 127.553 94.260  1.00 6.97   ? 154 ASP B C     1 
ATOM   2728 O O     . ASP B 2 165 ? 135.893 127.518 94.738  1.00 9.05   ? 154 ASP B O     1 
ATOM   2729 C CB    . ASP B 2 165 ? 133.987 125.259 94.858  1.00 2.41   ? 154 ASP B CB    1 
ATOM   2730 C CG    . ASP B 2 165 ? 133.310 124.455 95.948  1.00 7.24   ? 154 ASP B CG    1 
ATOM   2731 O OD1   . ASP B 2 165 ? 133.048 125.020 97.030  1.00 7.11   ? 154 ASP B OD1   1 
ATOM   2732 O OD2   . ASP B 2 165 ? 133.042 123.257 95.725  1.00 10.71  ? 154 ASP B OD2   1 
ATOM   2733 N N     . ASN B 2 166 ? 134.455 128.270 93.175  1.00 3.95   ? 155 ASN B N     1 
ATOM   2734 C CA    . ASN B 2 166 ? 135.471 128.992 92.426  1.00 4.28   ? 155 ASN B CA    1 
ATOM   2735 C C     . ASN B 2 166 ? 135.212 130.486 92.293  1.00 5.95   ? 155 ASN B C     1 
ATOM   2736 O O     . ASN B 2 166 ? 136.125 131.215 91.890  1.00 7.57   ? 155 ASN B O     1 
ATOM   2737 C CB    . ASN B 2 166 ? 135.626 128.391 91.020  1.00 5.56   ? 155 ASN B CB    1 
ATOM   2738 C CG    . ASN B 2 166 ? 136.963 128.720 90.392  1.00 8.01   ? 155 ASN B CG    1 
ATOM   2739 O OD1   . ASN B 2 166 ? 138.014 128.474 90.981  1.00 6.94   ? 155 ASN B OD1   1 
ATOM   2740 N ND2   . ASN B 2 166 ? 136.930 129.282 89.190  1.00 6.41   ? 155 ASN B ND2   1 
ATOM   2741 N N     . GLN B 2 167 ? 134.013 130.966 92.611  1.00 6.81   ? 156 GLN B N     1 
ATOM   2742 C CA    . GLN B 2 167 ? 133.707 132.384 92.490  1.00 4.67   ? 156 GLN B CA    1 
ATOM   2743 C C     . GLN B 2 167 ? 133.024 132.876 93.757  1.00 0.43   ? 156 GLN B C     1 
ATOM   2744 O O     . GLN B 2 167 ? 132.283 132.131 94.403  1.00 0.66   ? 156 GLN B O     1 
ATOM   2745 C CB    . GLN B 2 167 ? 132.827 132.665 91.265  1.00 2.52   ? 156 GLN B CB    1 
ATOM   2746 C CG    . GLN B 2 167 ? 131.622 131.756 91.135  1.00 5.60   ? 156 GLN B CG    1 
ATOM   2747 C CD    . GLN B 2 167 ? 130.914 131.926 89.807  1.00 8.63   ? 156 GLN B CD    1 
ATOM   2748 O OE1   . GLN B 2 167 ? 131.297 132.763 88.990  1.00 8.10   ? 156 GLN B OE1   1 
ATOM   2749 N NE2   . GLN B 2 167 ? 129.876 131.129 89.582  1.00 7.03   ? 156 GLN B NE2   1 
ATOM   2750 N N     . ILE B 2 168 ? 133.281 134.134 94.103  1.00 0.00   ? 157 ILE B N     1 
ATOM   2751 C CA    . ILE B 2 168 ? 132.752 134.736 95.322  1.00 1.84   ? 157 ILE B CA    1 
ATOM   2752 C C     . ILE B 2 168 ? 132.600 136.234 95.093  1.00 1.34   ? 157 ILE B C     1 
ATOM   2753 O O     . ILE B 2 168 ? 133.454 136.869 94.470  1.00 2.89   ? 157 ILE B O     1 
ATOM   2754 C CB    . ILE B 2 168 ? 133.661 134.427 96.534  1.00 0.44   ? 157 ILE B CB    1 
ATOM   2755 C CG1   . ILE B 2 168 ? 133.116 135.067 97.811  1.00 0.00   ? 157 ILE B CG1   1 
ATOM   2756 C CG2   . ILE B 2 168 ? 135.089 134.874 96.268  1.00 1.00   ? 157 ILE B CG2   1 
ATOM   2757 C CD1   . ILE B 2 168 ? 133.720 134.505 99.075  1.00 0.00   ? 157 ILE B CD1   1 
ATOM   2758 N N     . VAL B 2 169 ? 131.498 136.794 95.586  1.00 2.66   ? 158 VAL B N     1 
ATOM   2759 C CA    . VAL B 2 169 ? 131.250 138.231 95.533  1.00 1.50   ? 158 VAL B CA    1 
ATOM   2760 C C     . VAL B 2 169 ? 131.570 138.822 96.897  1.00 3.65   ? 158 VAL B C     1 
ATOM   2761 O O     . VAL B 2 169 ? 131.043 138.368 97.920  1.00 5.38   ? 158 VAL B O     1 
ATOM   2762 C CB    . VAL B 2 169 ? 129.800 138.542 95.123  1.00 1.55   ? 158 VAL B CB    1 
ATOM   2763 C CG1   . VAL B 2 169 ? 129.477 139.999 95.395  1.00 1.32   ? 158 VAL B CG1   1 
ATOM   2764 C CG2   . VAL B 2 169 ? 129.593 138.240 93.653  1.00 5.13   ? 158 VAL B CG2   1 
ATOM   2765 N N     . THR B 2 170 ? 132.441 139.828 96.913  1.00 0.00   ? 159 THR B N     1 
ATOM   2766 C CA    . THR B 2 170 ? 132.891 140.468 98.140  1.00 2.57   ? 159 THR B CA    1 
ATOM   2767 C C     . THR B 2 170 ? 132.663 141.968 98.038  1.00 2.84   ? 159 THR B C     1 
ATOM   2768 O O     . THR B 2 170 ? 132.994 142.581 97.018  1.00 2.63   ? 159 THR B O     1 
ATOM   2769 C CB    . THR B 2 170 ? 134.374 140.184 98.405  1.00 2.13   ? 159 THR B CB    1 
ATOM   2770 O OG1   . THR B 2 170 ? 135.176 140.869 97.435  1.00 0.92   ? 159 THR B OG1   1 
ATOM   2771 C CG2   . THR B 2 170 ? 134.663 138.692 98.330  1.00 2.84   ? 159 THR B CG2   1 
ATOM   2772 N N     . SER B 2 171 ? 132.105 142.554 99.092  1.00 0.28   ? 160 SER B N     1 
ATOM   2773 C CA    . SER B 2 171 ? 131.920 143.994 99.179  1.00 0.00   ? 160 SER B CA    1 
ATOM   2774 C C     . SER B 2 171 ? 132.979 144.599 100.089 1.00 0.00   ? 160 SER B C     1 
ATOM   2775 O O     . SER B 2 171 ? 133.384 144.001 101.089 1.00 3.69   ? 160 SER B O     1 
ATOM   2776 C CB    . SER B 2 171 ? 130.527 144.349 99.702  1.00 0.00   ? 160 SER B CB    1 
ATOM   2777 O OG    . SER B 2 171 ? 130.358 143.929 101.042 1.00 1.71   ? 160 SER B OG    1 
ATOM   2778 N N     . SER B 2 172 ? 133.414 145.803 99.740  1.00 2.19   ? 161 SER B N     1 
ATOM   2779 C CA    . SER B 2 172 ? 134.511 146.454 100.432 1.00 2.13   ? 161 SER B CA    1 
ATOM   2780 C C     . SER B 2 172 ? 134.124 147.874 100.814 1.00 0.29   ? 161 SER B C     1 
ATOM   2781 O O     . SER B 2 172 ? 133.115 148.415 100.354 1.00 0.00   ? 161 SER B O     1 
ATOM   2782 C CB    . SER B 2 172 ? 135.777 146.467 99.570  1.00 0.64   ? 161 SER B CB    1 
ATOM   2783 O OG    . SER B 2 172 ? 136.803 147.229 100.176 1.00 0.99   ? 161 SER B OG    1 
ATOM   2784 N N     . GLY B 2 173 ? 134.948 148.473 101.668 1.00 3.45   ? 162 GLY B N     1 
ATOM   2785 C CA    . GLY B 2 173 ? 134.787 149.851 102.071 1.00 1.16   ? 162 GLY B CA    1 
ATOM   2786 C C     . GLY B 2 173 ? 135.275 150.867 101.069 1.00 0.52   ? 162 GLY B C     1 
ATOM   2787 O O     . GLY B 2 173 ? 135.177 152.071 101.319 1.00 1.49   ? 162 GLY B O     1 
ATOM   2788 N N     . ASP B 2 174 ? 135.809 150.416 99.935  1.00 2.77   ? 163 ASP B N     1 
ATOM   2789 C CA    . ASP B 2 174 ? 136.225 151.298 98.855  1.00 2.83   ? 163 ASP B CA    1 
ATOM   2790 C C     . ASP B 2 174 ? 135.091 151.604 97.882  1.00 4.45   ? 163 ASP B C     1 
ATOM   2791 O O     . ASP B 2 174 ? 135.356 151.948 96.724  1.00 2.96   ? 163 ASP B O     1 
ATOM   2792 C CB    . ASP B 2 174 ? 137.420 150.696 98.112  1.00 1.34   ? 163 ASP B CB    1 
ATOM   2793 C CG    . ASP B 2 174 ? 137.079 149.410 97.383  1.00 5.54   ? 163 ASP B CG    1 
ATOM   2794 O OD1   . ASP B 2 174 ? 135.979 148.863 97.600  1.00 3.97   ? 163 ASP B OD1   1 
ATOM   2795 O OD2   . ASP B 2 174 ? 137.918 148.941 96.586  1.00 10.14  ? 163 ASP B OD2   1 
ATOM   2796 N N     . THR B 2 175 ? 133.840 151.473 98.329  1.00 1.40   ? 164 THR B N     1 
ATOM   2797 C CA    . THR B 2 175 ? 132.638 151.792 97.562  1.00 1.35   ? 164 THR B CA    1 
ATOM   2798 C C     . THR B 2 175 ? 132.461 150.907 96.334  1.00 3.67   ? 164 THR B C     1 
ATOM   2799 O O     . THR B 2 175 ? 131.718 151.266 95.416  1.00 6.41   ? 164 THR B O     1 
ATOM   2800 C CB    . THR B 2 175 ? 132.609 153.268 97.141  1.00 4.98   ? 164 THR B CB    1 
ATOM   2801 O OG1   . THR B 2 175 ? 133.527 153.480 96.061  1.00 3.06   ? 164 THR B OG1   1 
ATOM   2802 C CG2   . THR B 2 175 ? 132.986 154.174 98.307  1.00 3.08   ? 164 THR B CG2   1 
ATOM   2803 N N     . THR B 2 176 ? 133.125 149.753 96.289  1.00 1.48   ? 165 THR B N     1 
ATOM   2804 C CA    . THR B 2 176 ? 133.030 148.842 95.158  1.00 0.48   ? 165 THR B CA    1 
ATOM   2805 C C     . THR B 2 176 ? 132.823 147.418 95.654  1.00 1.46   ? 165 THR B C     1 
ATOM   2806 O O     . THR B 2 176 ? 133.179 147.070 96.782  1.00 3.35   ? 165 THR B O     1 
ATOM   2807 C CB    . THR B 2 176 ? 134.285 148.888 94.266  1.00 0.84   ? 165 THR B CB    1 
ATOM   2808 O OG1   . THR B 2 176 ? 135.387 148.287 94.956  1.00 0.34   ? 165 THR B OG1   1 
ATOM   2809 C CG2   . THR B 2 176 ? 134.642 150.318 93.891  1.00 4.09   ? 165 THR B CG2   1 
ATOM   2810 N N     . CYS B 2 177 ? 132.231 146.599 94.792  1.00 3.60   ? 166 CYS B N     1 
ATOM   2811 C CA    . CYS B 2 177 ? 132.126 145.164 95.003  1.00 0.00   ? 166 CYS B CA    1 
ATOM   2812 C C     . CYS B 2 177 ? 132.928 144.438 93.931  1.00 1.40   ? 166 CYS B C     1 
ATOM   2813 O O     . CYS B 2 177 ? 133.270 145.007 92.893  1.00 7.38   ? 166 CYS B O     1 
ATOM   2814 C CB    . CYS B 2 177 ? 130.665 144.700 94.975  1.00 1.56   ? 166 CYS B CB    1 
ATOM   2815 S SG    . CYS B 2 177 ? 129.520 145.757 95.887  1.00 13.11  ? 166 CYS B SG    1 
ATOM   2816 N N     . ALA B 2 178 ? 133.227 143.168 94.184  1.00 1.75   ? 167 ALA B N     1 
ATOM   2817 C CA    . ALA B 2 178 ? 134.043 142.413 93.244  1.00 1.69   ? 167 ALA B CA    1 
ATOM   2818 C C     . ALA B 2 178 ? 133.626 140.953 93.232  1.00 5.45   ? 167 ALA B C     1 
ATOM   2819 O O     . ALA B 2 178 ? 133.528 140.322 94.287  1.00 8.85   ? 167 ALA B O     1 
ATOM   2820 C CB    . ALA B 2 178 ? 135.530 142.532 93.590  1.00 0.49   ? 167 ALA B CB    1 
ATOM   2821 N N     . LEU B 2 179 ? 133.383 140.427 92.036  1.00 2.43   ? 168 LEU B N     1 
ATOM   2822 C CA    . LEU B 2 179 ? 133.235 138.995 91.822  1.00 0.44   ? 168 LEU B CA    1 
ATOM   2823 C C     . LEU B 2 179 ? 134.589 138.442 91.398  1.00 2.71   ? 168 LEU B C     1 
ATOM   2824 O O     . LEU B 2 179 ? 135.150 138.875 90.384  1.00 4.32   ? 168 LEU B O     1 
ATOM   2825 C CB    . LEU B 2 179 ? 132.174 138.707 90.762  1.00 2.67   ? 168 LEU B CB    1 
ATOM   2826 C CG    . LEU B 2 179 ? 132.154 137.288 90.193  1.00 6.93   ? 168 LEU B CG    1 
ATOM   2827 C CD1   . LEU B 2 179 ? 131.547 136.312 91.188  1.00 2.18   ? 168 LEU B CD1   1 
ATOM   2828 C CD2   . LEU B 2 179 ? 131.401 137.254 88.874  1.00 4.96   ? 168 LEU B CD2   1 
ATOM   2829 N N     . TRP B 2 180 ? 135.108 137.494 92.173  1.00 2.15   ? 169 TRP B N     1 
ATOM   2830 C CA    . TRP B 2 180 ? 136.460 136.983 92.018  1.00 2.28   ? 169 TRP B CA    1 
ATOM   2831 C C     . TRP B 2 180 ? 136.455 135.604 91.374  1.00 5.20   ? 169 TRP B C     1 
ATOM   2832 O O     . TRP B 2 180 ? 135.432 134.917 91.318  1.00 4.83   ? 169 TRP B O     1 
ATOM   2833 C CB    . TRP B 2 180 ? 137.174 136.892 93.371  1.00 2.22   ? 169 TRP B CB    1 
ATOM   2834 C CG    . TRP B 2 180 ? 137.238 138.172 94.137  1.00 3.33   ? 169 TRP B CG    1 
ATOM   2835 C CD1   . TRP B 2 180 ? 136.219 138.777 94.811  1.00 0.34   ? 169 TRP B CD1   1 
ATOM   2836 C CD2   . TRP B 2 180 ? 138.392 138.995 94.332  1.00 3.64   ? 169 TRP B CD2   1 
ATOM   2837 N NE1   . TRP B 2 180 ? 136.663 139.932 95.404  1.00 0.17   ? 169 TRP B NE1   1 
ATOM   2838 C CE2   . TRP B 2 180 ? 137.995 140.088 95.125  1.00 1.91   ? 169 TRP B CE2   1 
ATOM   2839 C CE3   . TRP B 2 180 ? 139.721 138.917 93.907  1.00 0.00   ? 169 TRP B CE3   1 
ATOM   2840 C CZ2   . TRP B 2 180 ? 138.879 141.095 95.502  1.00 2.27   ? 169 TRP B CZ2   1 
ATOM   2841 C CZ3   . TRP B 2 180 ? 140.596 139.914 94.284  1.00 0.95   ? 169 TRP B CZ3   1 
ATOM   2842 C CH2   . TRP B 2 180 ? 140.172 140.990 95.072  1.00 3.90   ? 169 TRP B CH2   1 
ATOM   2843 N N     . ASP B 2 181 ? 137.628 135.211 90.887  1.00 8.88   ? 170 ASP B N     1 
ATOM   2844 C CA    . ASP B 2 181 ? 137.912 133.840 90.481  1.00 4.01   ? 170 ASP B CA    1 
ATOM   2845 C C     . ASP B 2 181 ? 138.921 133.286 91.479  1.00 5.56   ? 170 ASP B C     1 
ATOM   2846 O O     . ASP B 2 181 ? 140.072 133.734 91.516  1.00 9.20   ? 170 ASP B O     1 
ATOM   2847 C CB    . ASP B 2 181 ? 138.450 133.785 89.053  1.00 5.22   ? 170 ASP B CB    1 
ATOM   2848 C CG    . ASP B 2 181 ? 138.405 132.387 88.465  1.00 10.72  ? 170 ASP B CG    1 
ATOM   2849 O OD1   . ASP B 2 181 ? 138.172 131.424 89.223  1.00 12.03  ? 170 ASP B OD1   1 
ATOM   2850 O OD2   . ASP B 2 181 ? 138.609 132.252 87.240  1.00 10.95  ? 170 ASP B OD2   1 
ATOM   2851 N N     . ILE B 2 182 ? 138.485 132.324 92.294  1.00 3.59   ? 171 ILE B N     1 
ATOM   2852 C CA    . ILE B 2 182 ? 139.327 131.829 93.380  1.00 3.96   ? 171 ILE B CA    1 
ATOM   2853 C C     . ILE B 2 182 ? 140.568 131.137 92.829  1.00 8.39   ? 171 ILE B C     1 
ATOM   2854 O O     . ILE B 2 182 ? 141.674 131.302 93.359  1.00 9.92   ? 171 ILE B O     1 
ATOM   2855 C CB    . ILE B 2 182 ? 138.517 130.898 94.302  1.00 3.52   ? 171 ILE B CB    1 
ATOM   2856 C CG1   . ILE B 2 182 ? 137.310 131.641 94.875  1.00 2.09   ? 171 ILE B CG1   1 
ATOM   2857 C CG2   . ILE B 2 182 ? 139.391 130.369 95.425  1.00 4.06   ? 171 ILE B CG2   1 
ATOM   2858 C CD1   . ILE B 2 182 ? 136.336 130.748 95.610  1.00 1.99   ? 171 ILE B CD1   1 
ATOM   2859 N N     . GLU B 2 183 ? 140.409 130.351 91.761  1.00 8.62   ? 172 GLU B N     1 
ATOM   2860 C CA    . GLU B 2 183 ? 141.545 129.622 91.205  1.00 6.66   ? 172 GLU B CA    1 
ATOM   2861 C C     . GLU B 2 183 ? 142.621 130.571 90.693  1.00 9.36   ? 172 GLU B C     1 
ATOM   2862 O O     . GLU B 2 183 ? 143.815 130.348 90.924  1.00 12.98  ? 172 GLU B O     1 
ATOM   2863 C CB    . GLU B 2 183 ? 141.076 128.693 90.085  1.00 6.61   ? 172 GLU B CB    1 
ATOM   2864 N N     . THR B 2 184 ? 142.221 131.635 89.999  1.00 6.91   ? 173 THR B N     1 
ATOM   2865 C CA    . THR B 2 184 ? 143.181 132.591 89.463  1.00 5.94   ? 173 THR B CA    1 
ATOM   2866 C C     . THR B 2 184 ? 143.541 133.687 90.455  1.00 9.41   ? 173 THR B C     1 
ATOM   2867 O O     . THR B 2 184 ? 144.636 134.256 90.365  1.00 9.31   ? 173 THR B O     1 
ATOM   2868 C CB    . THR B 2 184 ? 142.637 133.227 88.181  1.00 7.54   ? 173 THR B CB    1 
ATOM   2869 O OG1   . THR B 2 184 ? 141.666 134.226 88.516  1.00 9.41   ? 173 THR B OG1   1 
ATOM   2870 C CG2   . THR B 2 184 ? 141.988 132.173 87.299  1.00 7.58   ? 173 THR B CG2   1 
ATOM   2871 N N     . GLY B 2 185 ? 142.654 133.995 91.397  1.00 9.01   ? 174 GLY B N     1 
ATOM   2872 C CA    . GLY B 2 185 ? 142.920 135.030 92.374  1.00 5.33   ? 174 GLY B CA    1 
ATOM   2873 C C     . GLY B 2 185 ? 142.694 136.444 91.895  1.00 7.32   ? 174 GLY B C     1 
ATOM   2874 O O     . GLY B 2 185 ? 143.104 137.385 92.584  1.00 12.84  ? 174 GLY B O     1 
ATOM   2875 N N     . GLN B 2 186 ? 142.057 136.629 90.743  1.00 4.83   ? 175 GLN B N     1 
ATOM   2876 C CA    . GLN B 2 186 ? 141.835 137.944 90.164  1.00 6.67   ? 175 GLN B CA    1 
ATOM   2877 C C     . GLN B 2 186 ? 140.351 138.284 90.161  1.00 7.50   ? 175 GLN B C     1 
ATOM   2878 O O     . GLN B 2 186 ? 139.486 137.405 90.177  1.00 7.49   ? 175 GLN B O     1 
ATOM   2879 C CB    . GLN B 2 186 ? 142.390 138.017 88.737  1.00 6.35   ? 175 GLN B CB    1 
ATOM   2880 C CG    . GLN B 2 186 ? 143.864 138.382 88.661  1.00 7.12   ? 175 GLN B CG    1 
ATOM   2881 C CD    . GLN B 2 186 ? 144.768 137.245 89.088  1.00 10.39  ? 175 GLN B CD    1 
ATOM   2882 O OE1   . GLN B 2 186 ? 145.491 137.351 90.079  1.00 8.97   ? 175 GLN B OE1   1 
ATOM   2883 N NE2   . GLN B 2 186 ? 144.735 136.149 88.340  1.00 9.25   ? 175 GLN B NE2   1 
ATOM   2884 N N     . GLN B 2 187 ? 140.068 139.585 90.141  1.00 5.39   ? 176 GLN B N     1 
ATOM   2885 C CA    . GLN B 2 187 ? 138.693 140.073 90.101  1.00 3.91   ? 176 GLN B CA    1 
ATOM   2886 C C     . GLN B 2 187 ? 138.106 139.818 88.719  1.00 6.57   ? 176 GLN B C     1 
ATOM   2887 O O     . GLN B 2 187 ? 138.488 140.472 87.744  1.00 7.47   ? 176 GLN B O     1 
ATOM   2888 C CB    . GLN B 2 187 ? 138.650 141.559 90.441  1.00 2.93   ? 176 GLN B CB    1 
ATOM   2889 C CG    . GLN B 2 187 ? 138.977 141.880 91.884  1.00 4.51   ? 176 GLN B CG    1 
ATOM   2890 C CD    . GLN B 2 187 ? 139.084 143.369 92.141  1.00 7.29   ? 176 GLN B CD    1 
ATOM   2891 O OE1   . GLN B 2 187 ? 139.543 144.126 91.286  1.00 9.75   ? 176 GLN B OE1   1 
ATOM   2892 N NE2   . GLN B 2 187 ? 138.663 143.797 93.324  1.00 4.32   ? 176 GLN B NE2   1 
ATOM   2893 N N     . THR B 2 188 ? 137.179 138.862 88.631  1.00 6.31   ? 177 THR B N     1 
ATOM   2894 C CA    . THR B 2 188 ? 136.501 138.610 87.365  1.00 5.42   ? 177 THR B CA    1 
ATOM   2895 C C     . THR B 2 188 ? 135.660 139.809 86.946  1.00 5.24   ? 177 THR B C     1 
ATOM   2896 O O     . THR B 2 188 ? 135.646 140.189 85.769  1.00 8.16   ? 177 THR B O     1 
ATOM   2897 C CB    . THR B 2 188 ? 135.635 137.354 87.474  1.00 7.19   ? 177 THR B CB    1 
ATOM   2898 O OG1   . THR B 2 188 ? 136.477 136.206 87.634  1.00 9.76   ? 177 THR B OG1   1 
ATOM   2899 C CG2   . THR B 2 188 ? 134.783 137.176 86.227  1.00 6.54   ? 177 THR B CG2   1 
ATOM   2900 N N     . THR B 2 189 ? 134.964 140.427 87.898  1.00 5.04   ? 178 THR B N     1 
ATOM   2901 C CA    . THR B 2 189 ? 134.100 141.562 87.605  1.00 5.80   ? 178 THR B CA    1 
ATOM   2902 C C     . THR B 2 189 ? 134.167 142.558 88.752  1.00 5.58   ? 178 THR B C     1 
ATOM   2903 O O     . THR B 2 189 ? 134.234 142.165 89.918  1.00 9.41   ? 178 THR B O     1 
ATOM   2904 C CB    . THR B 2 189 ? 132.648 141.110 87.377  1.00 6.09   ? 178 THR B CB    1 
ATOM   2905 O OG1   . THR B 2 189 ? 132.604 140.169 86.298  1.00 7.66   ? 178 THR B OG1   1 
ATOM   2906 C CG2   . THR B 2 189 ? 131.759 142.294 87.029  1.00 7.41   ? 178 THR B CG2   1 
ATOM   2907 N N     . THR B 2 190 ? 134.158 143.845 88.420  1.00 4.27   ? 179 THR B N     1 
ATOM   2908 C CA    . THR B 2 190 ? 134.152 144.915 89.409  1.00 5.31   ? 179 THR B CA    1 
ATOM   2909 C C     . THR B 2 190 ? 132.863 145.715 89.278  1.00 5.63   ? 179 THR B C     1 
ATOM   2910 O O     . THR B 2 190 ? 132.503 146.144 88.177  1.00 10.83  ? 179 THR B O     1 
ATOM   2911 C CB    . THR B 2 190 ? 135.364 145.833 89.239  1.00 5.94   ? 179 THR B CB    1 
ATOM   2912 O OG1   . THR B 2 190 ? 136.552 145.040 89.121  1.00 7.69   ? 179 THR B OG1   1 
ATOM   2913 C CG2   . THR B 2 190 ? 135.500 146.757 90.437  1.00 4.76   ? 179 THR B CG2   1 
ATOM   2914 N N     . PHE B 2 191 ? 132.175 145.912 90.398  1.00 5.06   ? 180 PHE B N     1 
ATOM   2915 C CA    . PHE B 2 191 ? 130.913 146.637 90.449  1.00 5.43   ? 180 PHE B CA    1 
ATOM   2916 C C     . PHE B 2 191 ? 131.146 147.967 91.152  1.00 4.85   ? 180 PHE B C     1 
ATOM   2917 O O     . PHE B 2 191 ? 131.413 147.996 92.359  1.00 5.11   ? 180 PHE B O     1 
ATOM   2918 C CB    . PHE B 2 191 ? 129.845 145.820 91.178  1.00 4.29   ? 180 PHE B CB    1 
ATOM   2919 C CG    . PHE B 2 191 ? 129.750 144.394 90.713  1.00 7.81   ? 180 PHE B CG    1 
ATOM   2920 C CD1   . PHE B 2 191 ? 128.960 144.054 89.629  1.00 8.35   ? 180 PHE B CD1   1 
ATOM   2921 C CD2   . PHE B 2 191 ? 130.448 143.391 91.365  1.00 5.99   ? 180 PHE B CD2   1 
ATOM   2922 C CE1   . PHE B 2 191 ? 128.870 142.744 89.202  1.00 6.16   ? 180 PHE B CE1   1 
ATOM   2923 C CE2   . PHE B 2 191 ? 130.362 142.080 90.942  1.00 5.05   ? 180 PHE B CE2   1 
ATOM   2924 C CZ    . PHE B 2 191 ? 129.572 141.756 89.859  1.00 3.19   ? 180 PHE B CZ    1 
ATOM   2925 N N     . THR B 2 192 ? 131.047 149.059 90.398  1.00 5.26   ? 181 THR B N     1 
ATOM   2926 C CA    . THR B 2 192 ? 131.287 150.400 90.904  1.00 6.91   ? 181 THR B CA    1 
ATOM   2927 C C     . THR B 2 192 ? 130.081 151.287 90.620  1.00 5.95   ? 181 THR B C     1 
ATOM   2928 O O     . THR B 2 192 ? 129.376 151.113 89.623  1.00 5.34   ? 181 THR B O     1 
ATOM   2929 C CB    . THR B 2 192 ? 132.540 151.026 90.275  1.00 6.69   ? 181 THR B CB    1 
ATOM   2930 O OG1   . THR B 2 192 ? 132.269 151.376 88.913  1.00 4.39   ? 181 THR B OG1   1 
ATOM   2931 C CG2   . THR B 2 192 ? 133.708 150.053 90.317  1.00 5.47   ? 181 THR B CG2   1 
ATOM   2932 N N     . GLY B 2 193 ? 129.879 152.274 91.488  1.00 7.47   ? 182 GLY B N     1 
ATOM   2933 C CA    . GLY B 2 193 ? 128.727 153.146 91.380  1.00 4.88   ? 182 GLY B CA    1 
ATOM   2934 C C     . GLY B 2 193 ? 128.183 153.602 92.717  1.00 4.94   ? 182 GLY B C     1 
ATOM   2935 O O     . GLY B 2 193 ? 127.540 154.652 92.802  1.00 8.82   ? 182 GLY B O     1 
ATOM   2936 N N     . HIS B 2 194 ? 128.427 152.824 93.769  1.00 4.11   ? 183 HIS B N     1 
ATOM   2937 C CA    . HIS B 2 194 ? 128.129 153.287 95.117  1.00 0.87   ? 183 HIS B CA    1 
ATOM   2938 C C     . HIS B 2 194 ? 129.054 154.443 95.477  1.00 4.71   ? 183 HIS B C     1 
ATOM   2939 O O     . HIS B 2 194 ? 130.263 154.381 95.233  1.00 8.98   ? 183 HIS B O     1 
ATOM   2940 C CB    . HIS B 2 194 ? 128.293 152.150 96.125  1.00 1.77   ? 183 HIS B CB    1 
ATOM   2941 C CG    . HIS B 2 194 ? 127.072 151.299 96.290  1.00 5.00   ? 183 HIS B CG    1 
ATOM   2942 N ND1   . HIS B 2 194 ? 125.826 151.826 96.554  1.00 7.00   ? 183 HIS B ND1   1 
ATOM   2943 C CD2   . HIS B 2 194 ? 126.910 149.956 96.246  1.00 2.24   ? 183 HIS B CD2   1 
ATOM   2944 C CE1   . HIS B 2 194 ? 124.948 150.844 96.657  1.00 1.31   ? 183 HIS B CE1   1 
ATOM   2945 N NE2   . HIS B 2 194 ? 125.580 149.699 96.474  1.00 0.00   ? 183 HIS B NE2   1 
ATOM   2946 N N     . THR B 2 195 ? 128.489 155.502 96.047  1.00 4.86   ? 184 THR B N     1 
ATOM   2947 C CA    . THR B 2 195 ? 129.281 156.638 96.497  1.00 3.82   ? 184 THR B CA    1 
ATOM   2948 C C     . THR B 2 195 ? 129.684 156.529 97.962  1.00 4.78   ? 184 THR B C     1 
ATOM   2949 O O     . THR B 2 195 ? 130.383 157.414 98.466  1.00 7.39   ? 184 THR B O     1 
ATOM   2950 C CB    . THR B 2 195 ? 128.518 157.946 96.264  1.00 4.72   ? 184 THR B CB    1 
ATOM   2951 O OG1   . THR B 2 195 ? 127.339 157.968 97.076  1.00 6.12   ? 184 THR B OG1   1 
ATOM   2952 C CG2   . THR B 2 195 ? 128.121 158.075 94.803  1.00 3.72   ? 184 THR B CG2   1 
ATOM   2953 N N     . GLY B 2 196 ? 129.262 155.465 98.652  1.00 4.89   ? 185 GLY B N     1 
ATOM   2954 C CA    . GLY B 2 196 ? 129.669 155.230 100.018 1.00 3.66   ? 185 GLY B CA    1 
ATOM   2955 C C     . GLY B 2 196 ? 130.155 153.801 100.187 1.00 4.06   ? 185 GLY B C     1 
ATOM   2956 O O     . GLY B 2 196 ? 130.045 152.974 99.279  1.00 6.61   ? 185 GLY B O     1 
ATOM   2957 N N     . ASP B 2 197 ? 130.701 153.527 101.369 1.00 3.24   ? 186 ASP B N     1 
ATOM   2958 C CA    . ASP B 2 197 ? 131.238 152.202 101.650 1.00 1.53   ? 186 ASP B CA    1 
ATOM   2959 C C     . ASP B 2 197 ? 130.121 151.167 101.644 1.00 1.85   ? 186 ASP B C     1 
ATOM   2960 O O     . ASP B 2 197 ? 129.092 151.346 102.300 1.00 5.84   ? 186 ASP B O     1 
ATOM   2961 C CB    . ASP B 2 197 ? 131.955 152.192 102.998 1.00 2.39   ? 186 ASP B CB    1 
ATOM   2962 C CG    . ASP B 2 197 ? 132.964 153.313 103.130 1.00 9.53   ? 186 ASP B CG    1 
ATOM   2963 O OD1   . ASP B 2 197 ? 133.243 153.988 102.118 1.00 9.08   ? 186 ASP B OD1   1 
ATOM   2964 O OD2   . ASP B 2 197 ? 133.482 153.514 104.247 1.00 7.41   ? 186 ASP B OD2   1 
ATOM   2965 N N     . VAL B 2 198 ? 130.330 150.079 100.911 1.00 0.00   ? 187 VAL B N     1 
ATOM   2966 C CA    . VAL B 2 198 ? 129.351 149.000 100.851 1.00 0.17   ? 187 VAL B CA    1 
ATOM   2967 C C     . VAL B 2 198 ? 129.474 148.159 102.113 1.00 1.36   ? 187 VAL B C     1 
ATOM   2968 O O     . VAL B 2 198 ? 130.560 147.670 102.443 1.00 3.68   ? 187 VAL B O     1 
ATOM   2969 C CB    . VAL B 2 198 ? 129.554 148.148 99.590  1.00 0.58   ? 187 VAL B CB    1 
ATOM   2970 C CG1   . VAL B 2 198 ? 128.355 147.248 99.367  1.00 0.70   ? 187 VAL B CG1   1 
ATOM   2971 C CG2   . VAL B 2 198 ? 129.790 149.037 98.382  1.00 0.89   ? 187 VAL B CG2   1 
ATOM   2972 N N     . MET B 2 199 ? 128.359 147.989 102.826 1.00 0.00   ? 188 MET B N     1 
ATOM   2973 C CA    . MET B 2 199 ? 128.383 147.345 104.129 1.00 0.00   ? 188 MET B CA    1 
ATOM   2974 C C     . MET B 2 199 ? 127.833 145.928 104.140 1.00 0.88   ? 188 MET B C     1 
ATOM   2975 O O     . MET B 2 199 ? 128.112 145.188 105.088 1.00 1.69   ? 188 MET B O     1 
ATOM   2976 C CB    . MET B 2 199 ? 127.601 148.183 105.151 1.00 0.19   ? 188 MET B CB    1 
ATOM   2977 C CG    . MET B 2 199 ? 128.158 149.581 105.368 1.00 0.00   ? 188 MET B CG    1 
ATOM   2978 S SD    . MET B 2 199 ? 129.935 149.599 105.670 1.00 5.33   ? 188 MET B SD    1 
ATOM   2979 C CE    . MET B 2 199 ? 130.051 148.552 107.118 1.00 0.62   ? 188 MET B CE    1 
ATOM   2980 N N     . SER B 2 200 ? 127.070 145.527 103.127 1.00 1.06   ? 189 SER B N     1 
ATOM   2981 C CA    . SER B 2 200 ? 126.447 144.213 103.144 1.00 1.79   ? 189 SER B CA    1 
ATOM   2982 C C     . SER B 2 200 ? 126.220 143.724 101.722 1.00 0.55   ? 189 SER B C     1 
ATOM   2983 O O     . SER B 2 200 ? 126.207 144.504 100.767 1.00 0.00   ? 189 SER B O     1 
ATOM   2984 C CB    . SER B 2 200 ? 125.121 144.234 103.915 1.00 0.86   ? 189 SER B CB    1 
ATOM   2985 O OG    . SER B 2 200 ? 124.302 145.307 103.487 1.00 2.74   ? 189 SER B OG    1 
ATOM   2986 N N     . LEU B 2 201 ? 126.043 142.410 101.601 1.00 3.44   ? 190 LEU B N     1 
ATOM   2987 C CA    . LEU B 2 201 ? 125.704 141.760 100.346 1.00 0.02   ? 190 LEU B CA    1 
ATOM   2988 C C     . LEU B 2 201 ? 124.600 140.743 100.582 1.00 0.00   ? 190 LEU B C     1 
ATOM   2989 O O     . LEU B 2 201 ? 124.420 140.241 101.694 1.00 0.88   ? 190 LEU B O     1 
ATOM   2990 C CB    . LEU B 2 201 ? 126.901 141.040 99.717  1.00 1.27   ? 190 LEU B CB    1 
ATOM   2991 C CG    . LEU B 2 201 ? 128.074 141.853 99.185  1.00 2.16   ? 190 LEU B CG    1 
ATOM   2992 C CD1   . LEU B 2 201 ? 129.254 140.934 98.953  1.00 0.00   ? 190 LEU B CD1   1 
ATOM   2993 C CD2   . LEU B 2 201 ? 127.693 142.573 97.909  1.00 3.62   ? 190 LEU B CD2   1 
ATOM   2994 N N     . SER B 2 202 ? 123.865 140.443 99.517  1.00 0.32   ? 191 SER B N     1 
ATOM   2995 C CA    . SER B 2 202 ? 122.888 139.366 99.532  1.00 0.01   ? 191 SER B CA    1 
ATOM   2996 C C     . SER B 2 202 ? 122.825 138.774 98.135  1.00 3.15   ? 191 SER B C     1 
ATOM   2997 O O     . SER B 2 202 ? 122.732 139.516 97.155  1.00 3.36   ? 191 SER B O     1 
ATOM   2998 C CB    . SER B 2 202 ? 121.507 139.863 99.966  1.00 1.10   ? 191 SER B CB    1 
ATOM   2999 O OG    . SER B 2 202 ? 120.673 138.777 100.330 1.00 3.65   ? 191 SER B OG    1 
ATOM   3000 N N     . LEU B 2 203 ? 122.883 137.451 98.049  1.00 4.63   ? 192 LEU B N     1 
ATOM   3001 C CA    . LEU B 2 203 ? 122.837 136.764 96.768  1.00 1.98   ? 192 LEU B CA    1 
ATOM   3002 C C     . LEU B 2 203 ? 121.431 136.250 96.498  1.00 2.84   ? 192 LEU B C     1 
ATOM   3003 O O     . LEU B 2 203 ? 120.769 135.716 97.392  1.00 7.81   ? 192 LEU B O     1 
ATOM   3004 C CB    . LEU B 2 203 ? 123.832 135.604 96.738  1.00 4.76   ? 192 LEU B CB    1 
ATOM   3005 C CG    . LEU B 2 203 ? 125.226 135.915 96.193  1.00 3.68   ? 192 LEU B CG    1 
ATOM   3006 C CD1   . LEU B 2 203 ? 126.151 134.732 96.401  1.00 2.55   ? 192 LEU B CD1   1 
ATOM   3007 C CD2   . LEU B 2 203 ? 125.155 136.291 94.722  1.00 3.46   ? 192 LEU B CD2   1 
ATOM   3008 N N     . ALA B 2 204 ? 120.980 136.422 95.259  1.00 0.31   ? 193 ALA B N     1 
ATOM   3009 C CA    . ALA B 2 204 ? 119.680 135.920 94.860  1.00 5.93   ? 193 ALA B CA    1 
ATOM   3010 C C     . ALA B 2 204 ? 119.685 134.393 94.866  1.00 12.76  ? 193 ALA B C     1 
ATOM   3011 O O     . ALA B 2 204 ? 120.743 133.767 94.765  1.00 11.67  ? 193 ALA B O     1 
ATOM   3012 C CB    . ALA B 2 204 ? 119.311 136.448 93.477  1.00 4.19   ? 193 ALA B CB    1 
ATOM   3013 N N     . PRO B 2 205 ? 118.510 133.770 95.005  1.00 12.41  ? 194 PRO B N     1 
ATOM   3014 C CA    . PRO B 2 205 ? 118.467 132.297 95.005  1.00 11.36  ? 194 PRO B CA    1 
ATOM   3015 C C     . PRO B 2 205 ? 119.085 131.669 93.767  1.00 12.75  ? 194 PRO B C     1 
ATOM   3016 O O     . PRO B 2 205 ? 119.717 130.610 93.868  1.00 14.07  ? 194 PRO B O     1 
ATOM   3017 C CB    . PRO B 2 205 ? 116.966 131.998 95.109  1.00 12.72  ? 194 PRO B CB    1 
ATOM   3018 C CG    . PRO B 2 205 ? 116.406 133.179 95.821  1.00 13.03  ? 194 PRO B CG    1 
ATOM   3019 C CD    . PRO B 2 205 ? 117.205 134.361 95.350  1.00 10.38  ? 194 PRO B CD    1 
ATOM   3020 N N     . ASP B 2 206 ? 118.926 132.290 92.600  1.00 10.05  ? 195 ASP B N     1 
ATOM   3021 C CA    . ASP B 2 206 ? 119.553 131.790 91.384  1.00 13.99  ? 195 ASP B CA    1 
ATOM   3022 C C     . ASP B 2 206 ? 120.993 132.259 91.222  1.00 16.87  ? 195 ASP B C     1 
ATOM   3023 O O     . ASP B 2 206 ? 121.659 131.837 90.270  1.00 15.62  ? 195 ASP B O     1 
ATOM   3024 C CB    . ASP B 2 206 ? 118.733 132.203 90.157  1.00 14.34  ? 195 ASP B CB    1 
ATOM   3025 C CG    . ASP B 2 206 ? 118.560 133.706 90.047  1.00 20.44  ? 195 ASP B CG    1 
ATOM   3026 O OD1   . ASP B 2 206 ? 118.951 134.426 90.988  1.00 21.04  ? 195 ASP B OD1   1 
ATOM   3027 O OD2   . ASP B 2 206 ? 118.032 134.169 89.014  1.00 22.00  ? 195 ASP B OD2   1 
ATOM   3028 N N     . THR B 2 207 ? 121.480 133.118 92.122  1.00 14.32  ? 196 THR B N     1 
ATOM   3029 C CA    . THR B 2 207 ? 122.849 133.644 92.093  1.00 13.88  ? 196 THR B CA    1 
ATOM   3030 C C     . THR B 2 207 ? 123.164 134.352 90.778  1.00 12.26  ? 196 THR B C     1 
ATOM   3031 O O     . THR B 2 207 ? 124.321 134.408 90.354  1.00 13.92  ? 196 THR B O     1 
ATOM   3032 C CB    . THR B 2 207 ? 123.887 132.549 92.368  1.00 14.54  ? 196 THR B CB    1 
ATOM   3033 O OG1   . THR B 2 207 ? 123.819 131.542 91.351  1.00 12.35  ? 196 THR B OG1   1 
ATOM   3034 C CG2   . THR B 2 207 ? 123.642 131.911 93.727  1.00 12.55  ? 196 THR B CG2   1 
ATOM   3035 N N     . ARG B 2 208 ? 122.141 134.900 90.123  1.00 11.34  ? 197 ARG B N     1 
ATOM   3036 C CA    . ARG B 2 208 ? 122.338 135.700 88.922  1.00 11.57  ? 197 ARG B CA    1 
ATOM   3037 C C     . ARG B 2 208 ? 122.340 137.196 89.201  1.00 14.10  ? 197 ARG B C     1 
ATOM   3038 O O     . ARG B 2 208 ? 122.849 137.964 88.377  1.00 12.83  ? 197 ARG B O     1 
ATOM   3039 C CB    . ARG B 2 208 ? 121.252 135.383 87.886  1.00 9.62   ? 197 ARG B CB    1 
ATOM   3040 N N     . LEU B 2 209 ? 121.786 137.620 90.334  1.00 13.26  ? 198 LEU B N     1 
ATOM   3041 C CA    . LEU B 2 209 ? 121.778 139.015 90.743  1.00 5.76   ? 198 LEU B CA    1 
ATOM   3042 C C     . LEU B 2 209 ? 122.145 139.088 92.216  1.00 5.20   ? 198 LEU B C     1 
ATOM   3043 O O     . LEU B 2 209 ? 122.038 138.104 92.951  1.00 8.91   ? 198 LEU B O     1 
ATOM   3044 C CB    . LEU B 2 209 ? 120.410 139.673 90.512  1.00 5.55   ? 198 LEU B CB    1 
ATOM   3045 C CG    . LEU B 2 209 ? 119.805 139.603 89.111  1.00 7.44   ? 198 LEU B CG    1 
ATOM   3046 C CD1   . LEU B 2 209 ? 118.298 139.775 89.180  1.00 7.18   ? 198 LEU B CD1   1 
ATOM   3047 C CD2   . LEU B 2 209 ? 120.424 140.655 88.207  1.00 9.47   ? 198 LEU B CD2   1 
ATOM   3048 N N     . PHE B 2 210 ? 122.593 140.265 92.645  1.00 3.80   ? 199 PHE B N     1 
ATOM   3049 C CA    . PHE B 2 210 ? 122.850 140.470 94.065  1.00 2.64   ? 199 PHE B CA    1 
ATOM   3050 C C     . PHE B 2 210 ? 122.648 141.934 94.428  1.00 0.66   ? 199 PHE B C     1 
ATOM   3051 O O     . PHE B 2 210 ? 122.944 142.826 93.633  1.00 0.73   ? 199 PHE B O     1 
ATOM   3052 C CB    . PHE B 2 210 ? 124.257 139.988 94.460  1.00 1.95   ? 199 PHE B CB    1 
ATOM   3053 C CG    . PHE B 2 210 ? 125.373 140.887 94.011  1.00 0.51   ? 199 PHE B CG    1 
ATOM   3054 C CD1   . PHE B 2 210 ? 125.929 140.743 92.753  1.00 1.73   ? 199 PHE B CD1   1 
ATOM   3055 C CD2   . PHE B 2 210 ? 125.885 141.858 94.856  1.00 1.23   ? 199 PHE B CD2   1 
ATOM   3056 C CE1   . PHE B 2 210 ? 126.963 141.556 92.341  1.00 3.99   ? 199 PHE B CE1   1 
ATOM   3057 C CE2   . PHE B 2 210 ? 126.915 142.678 94.446  1.00 2.88   ? 199 PHE B CE2   1 
ATOM   3058 C CZ    . PHE B 2 210 ? 127.455 142.527 93.188  1.00 6.83   ? 199 PHE B CZ    1 
ATOM   3059 N N     . VAL B 2 211 ? 122.136 142.171 95.633  1.00 1.45   ? 200 VAL B N     1 
ATOM   3060 C CA    . VAL B 2 211 ? 121.888 143.519 96.132  1.00 0.00   ? 200 VAL B CA    1 
ATOM   3061 C C     . VAL B 2 211 ? 122.968 143.877 97.140  1.00 0.75   ? 200 VAL B C     1 
ATOM   3062 O O     . VAL B 2 211 ? 123.333 143.066 98.000  1.00 2.88   ? 200 VAL B O     1 
ATOM   3063 C CB    . VAL B 2 211 ? 120.485 143.651 96.758  1.00 0.00   ? 200 VAL B CB    1 
ATOM   3064 C CG1   . VAL B 2 211 ? 119.419 143.680 95.680  1.00 0.66   ? 200 VAL B CG1   1 
ATOM   3065 C CG2   . VAL B 2 211 ? 120.224 142.529 97.749  1.00 0.00   ? 200 VAL B CG2   1 
ATOM   3066 N N     . SER B 2 212 ? 123.493 145.091 97.022  1.00 1.68   ? 201 SER B N     1 
ATOM   3067 C CA    . SER B 2 212 ? 124.500 145.601 97.941  1.00 0.00   ? 201 SER B CA    1 
ATOM   3068 C C     . SER B 2 212 ? 124.051 146.951 98.474  1.00 0.00   ? 201 SER B C     1 
ATOM   3069 O O     . SER B 2 212 ? 123.761 147.861 97.694  1.00 2.21   ? 201 SER B O     1 
ATOM   3070 C CB    . SER B 2 212 ? 125.862 145.727 97.252  1.00 2.06   ? 201 SER B CB    1 
ATOM   3071 O OG    . SER B 2 212 ? 125.884 146.829 96.363  1.00 5.92   ? 201 SER B OG    1 
ATOM   3072 N N     . GLY B 2 213 ? 123.986 147.076 99.795  1.00 0.49   ? 202 GLY B N     1 
ATOM   3073 C CA    . GLY B 2 213 ? 123.661 148.337 100.441 1.00 0.91   ? 202 GLY B CA    1 
ATOM   3074 C C     . GLY B 2 213 ? 124.930 149.029 100.906 1.00 1.00   ? 202 GLY B C     1 
ATOM   3075 O O     . GLY B 2 213 ? 125.858 148.382 101.392 1.00 2.97   ? 202 GLY B O     1 
ATOM   3076 N N     . ALA B 2 214 ? 124.965 150.350 100.751 1.00 0.00   ? 203 ALA B N     1 
ATOM   3077 C CA    . ALA B 2 214 ? 126.173 151.105 101.052 1.00 0.00   ? 203 ALA B CA    1 
ATOM   3078 C C     . ALA B 2 214 ? 125.857 152.227 102.033 1.00 3.71   ? 203 ALA B C     1 
ATOM   3079 O O     . ALA B 2 214 ? 124.712 152.415 102.456 1.00 6.27   ? 203 ALA B O     1 
ATOM   3080 C CB    . ALA B 2 214 ? 126.811 151.660 99.773  1.00 1.76   ? 203 ALA B CB    1 
ATOM   3081 N N     . CYS B 2 215 ? 126.899 152.978 102.396 1.00 4.18   ? 204 CYS B N     1 
ATOM   3082 C CA    . CYS B 2 215 ? 126.762 154.093 103.324 1.00 4.30   ? 204 CYS B CA    1 
ATOM   3083 C C     . CYS B 2 215 ? 126.154 155.328 102.676 1.00 5.28   ? 204 CYS B C     1 
ATOM   3084 O O     . CYS B 2 215 ? 125.908 156.315 103.376 1.00 6.16   ? 204 CYS B O     1 
ATOM   3085 C CB    . CYS B 2 215 ? 128.122 154.445 103.928 1.00 6.06   ? 204 CYS B CB    1 
ATOM   3086 S SG    . CYS B 2 215 ? 128.819 153.165 104.993 1.00 17.07  ? 204 CYS B SG    1 
ATOM   3087 N N     . ASP B 2 216 ? 125.911 155.304 101.369 1.00 5.77   ? 205 ASP B N     1 
ATOM   3088 C CA    . ASP B 2 216 ? 125.224 156.396 100.695 1.00 5.88   ? 205 ASP B CA    1 
ATOM   3089 C C     . ASP B 2 216 ? 123.711 156.306 100.833 1.00 7.23   ? 205 ASP B C     1 
ATOM   3090 O O     . ASP B 2 216 ? 122.991 156.930 100.042 1.00 5.16   ? 205 ASP B O     1 
ATOM   3091 C CB    . ASP B 2 216 ? 125.620 156.436 99.217  1.00 4.25   ? 205 ASP B CB    1 
ATOM   3092 C CG    . ASP B 2 216 ? 125.322 155.137 98.495  1.00 5.63   ? 205 ASP B CG    1 
ATOM   3093 O OD1   . ASP B 2 216 ? 124.961 154.149 99.165  1.00 8.14   ? 205 ASP B OD1   1 
ATOM   3094 O OD2   . ASP B 2 216 ? 125.451 155.102 97.254  1.00 7.08   ? 205 ASP B OD2   1 
ATOM   3095 N N     . ALA B 2 217 ? 123.229 155.538 101.814 1.00 6.21   ? 206 ALA B N     1 
ATOM   3096 C CA    . ALA B 2 217 ? 121.801 155.330 102.050 1.00 3.46   ? 206 ALA B CA    1 
ATOM   3097 C C     . ALA B 2 217 ? 121.112 154.737 100.827 1.00 6.58   ? 206 ALA B C     1 
ATOM   3098 O O     . ALA B 2 217 ? 119.935 155.003 100.573 1.00 9.24   ? 206 ALA B O     1 
ATOM   3099 C CB    . ALA B 2 217 ? 121.111 156.627 102.480 1.00 4.20   ? 206 ALA B CB    1 
ATOM   3100 N N     . SER B 2 218 ? 121.839 153.927 100.062 1.00 4.17   ? 207 SER B N     1 
ATOM   3101 C CA    . SER B 2 218 ? 121.323 153.377 98.820  1.00 2.35   ? 207 SER B CA    1 
ATOM   3102 C C     . SER B 2 218 ? 121.697 151.909 98.695  1.00 2.24   ? 207 SER B C     1 
ATOM   3103 O O     . SER B 2 218 ? 122.779 151.488 99.123  1.00 4.79   ? 207 SER B O     1 
ATOM   3104 C CB    . SER B 2 218 ? 121.853 154.153 97.608  1.00 5.84   ? 207 SER B CB    1 
ATOM   3105 O OG    . SER B 2 218 ? 121.380 153.593 96.396  1.00 10.23  ? 207 SER B OG    1 
ATOM   3106 N N     . ALA B 2 219 ? 120.793 151.140 98.096  1.00 2.64   ? 208 ALA B N     1 
ATOM   3107 C CA    . ALA B 2 219 ? 121.040 149.760 97.719  1.00 0.85   ? 208 ALA B CA    1 
ATOM   3108 C C     . ALA B 2 219 ? 121.092 149.664 96.201  1.00 1.71   ? 208 ALA B C     1 
ATOM   3109 O O     . ALA B 2 219 ? 120.451 150.442 95.493  1.00 3.10   ? 208 ALA B O     1 
ATOM   3110 C CB    . ALA B 2 219 ? 119.958 148.828 98.270  1.00 0.89   ? 208 ALA B CB    1 
ATOM   3111 N N     . LYS B 2 220 ? 121.880 148.722 95.701  1.00 3.18   ? 209 LYS B N     1 
ATOM   3112 C CA    . LYS B 2 220 ? 122.038 148.544 94.266  1.00 2.19   ? 209 LYS B CA    1 
ATOM   3113 C C     . LYS B 2 220 ? 121.860 147.078 93.909  1.00 3.45   ? 209 LYS B C     1 
ATOM   3114 O O     . LYS B 2 220 ? 122.479 146.204 94.525  1.00 5.47   ? 209 LYS B O     1 
ATOM   3115 C CB    . LYS B 2 220 ? 123.401 149.054 93.792  1.00 2.14   ? 209 LYS B CB    1 
ATOM   3116 C CG    . LYS B 2 220 ? 123.428 150.550 93.525  1.00 2.22   ? 209 LYS B CG    1 
ATOM   3117 C CD    . LYS B 2 220 ? 124.798 151.016 93.070  1.00 4.55   ? 209 LYS B CD    1 
ATOM   3118 C CE    . LYS B 2 220 ? 124.766 152.474 92.648  1.00 3.88   ? 209 LYS B CE    1 
ATOM   3119 N NZ    . LYS B 2 220 ? 124.361 153.368 93.766  1.00 5.83   ? 209 LYS B NZ    1 
ATOM   3120 N N     . LEU B 2 221 ? 121.001 146.823 92.927  1.00 4.32   ? 210 LEU B N     1 
ATOM   3121 C CA    . LEU B 2 221 ? 120.816 145.508 92.333  1.00 2.40   ? 210 LEU B CA    1 
ATOM   3122 C C     . LEU B 2 221 ? 121.773 145.375 91.159  1.00 4.65   ? 210 LEU B C     1 
ATOM   3123 O O     . LEU B 2 221 ? 121.651 146.111 90.170  1.00 9.58   ? 210 LEU B O     1 
ATOM   3124 C CB    . LEU B 2 221 ? 119.374 145.319 91.864  1.00 3.59   ? 210 LEU B CB    1 
ATOM   3125 C CG    . LEU B 2 221 ? 119.048 143.981 91.198  1.00 4.98   ? 210 LEU B CG    1 
ATOM   3126 C CD1   . LEU B 2 221 ? 119.232 142.822 92.165  1.00 4.58   ? 210 LEU B CD1   1 
ATOM   3127 C CD2   . LEU B 2 221 ? 117.646 143.999 90.617  1.00 6.09   ? 210 LEU B CD2   1 
ATOM   3128 N N     . TRP B 2 222 ? 122.700 144.424 91.268  1.00 5.48   ? 211 TRP B N     1 
ATOM   3129 C CA    . TRP B 2 222 ? 123.780 144.194 90.325  1.00 5.46   ? 211 TRP B CA    1 
ATOM   3130 C C     . TRP B 2 222 ? 123.578 142.857 89.626  1.00 7.94   ? 211 TRP B C     1 
ATOM   3131 O O     . TRP B 2 222 ? 123.142 141.878 90.242  1.00 8.54   ? 211 TRP B O     1 
ATOM   3132 C CB    . TRP B 2 222 ? 125.133 144.163 91.044  1.00 4.19   ? 211 TRP B CB    1 
ATOM   3133 C CG    . TRP B 2 222 ? 125.576 145.462 91.619  1.00 6.74   ? 211 TRP B CG    1 
ATOM   3134 C CD1   . TRP B 2 222 ? 125.398 145.891 92.901  1.00 2.67   ? 211 TRP B CD1   1 
ATOM   3135 C CD2   . TRP B 2 222 ? 126.297 146.496 90.945  1.00 7.82   ? 211 TRP B CD2   1 
ATOM   3136 N NE1   . TRP B 2 222 ? 125.953 147.135 93.064  1.00 4.82   ? 211 TRP B NE1   1 
ATOM   3137 C CE2   . TRP B 2 222 ? 126.511 147.529 91.876  1.00 4.17   ? 211 TRP B CE2   1 
ATOM   3138 C CE3   . TRP B 2 222 ? 126.777 146.650 89.643  1.00 7.80   ? 211 TRP B CE3   1 
ATOM   3139 C CZ2   . TRP B 2 222 ? 127.183 148.699 91.547  1.00 4.79   ? 211 TRP B CZ2   1 
ATOM   3140 C CZ3   . TRP B 2 222 ? 127.443 147.811 89.319  1.00 10.44  ? 211 TRP B CZ3   1 
ATOM   3141 C CH2   . TRP B 2 222 ? 127.639 148.820 90.265  1.00 8.54   ? 211 TRP B CH2   1 
ATOM   3142 N N     . ASP B 2 223 ? 123.922 142.821 88.341  1.00 9.67   ? 212 ASP B N     1 
ATOM   3143 C CA    . ASP B 2 223 ? 123.950 141.581 87.578  1.00 9.23   ? 212 ASP B CA    1 
ATOM   3144 C C     . ASP B 2 223 ? 125.328 140.945 87.709  1.00 10.79  ? 212 ASP B C     1 
ATOM   3145 O O     . ASP B 2 223 ? 126.343 141.588 87.426  1.00 13.59  ? 212 ASP B O     1 
ATOM   3146 C CB    . ASP B 2 223 ? 123.621 141.841 86.107  1.00 11.18  ? 212 ASP B CB    1 
ATOM   3147 C CG    . ASP B 2 223 ? 123.158 140.592 85.381  1.00 15.07  ? 212 ASP B CG    1 
ATOM   3148 O OD1   . ASP B 2 223 ? 123.716 139.504 85.638  1.00 11.70  ? 212 ASP B OD1   1 
ATOM   3149 O OD2   . ASP B 2 223 ? 122.234 140.697 84.548  1.00 17.19  ? 212 ASP B OD2   1 
ATOM   3150 N N     . VAL B 2 224 ? 125.359 139.685 88.145  1.00 8.19   ? 213 VAL B N     1 
ATOM   3151 C CA    . VAL B 2 224 ? 126.633 139.009 88.370  1.00 8.18   ? 213 VAL B CA    1 
ATOM   3152 C C     . VAL B 2 224 ? 127.351 138.762 87.048  1.00 13.38  ? 213 VAL B C     1 
ATOM   3153 O O     . VAL B 2 224 ? 128.546 139.047 86.908  1.00 14.56  ? 213 VAL B O     1 
ATOM   3154 C CB    . VAL B 2 224 ? 126.414 137.698 89.144  1.00 9.96   ? 213 VAL B CB    1 
ATOM   3155 C CG1   . VAL B 2 224 ? 127.697 136.886 89.187  1.00 10.85  ? 213 VAL B CG1   1 
ATOM   3156 C CG2   . VAL B 2 224 ? 125.914 137.989 90.547  1.00 11.31  ? 213 VAL B CG2   1 
ATOM   3157 N N     . ARG B 2 225 ? 126.632 138.234 86.056  1.00 17.54  ? 214 ARG B N     1 
ATOM   3158 C CA    . ARG B 2 225 ? 127.262 137.890 84.786  1.00 16.53  ? 214 ARG B CA    1 
ATOM   3159 C C     . ARG B 2 225 ? 127.468 139.121 83.912  1.00 14.45  ? 214 ARG B C     1 
ATOM   3160 O O     . ARG B 2 225 ? 128.562 139.335 83.378  1.00 18.43  ? 214 ARG B O     1 
ATOM   3161 C CB    . ARG B 2 225 ? 126.421 136.844 84.051  1.00 12.63  ? 214 ARG B CB    1 
ATOM   3162 N N     . GLU B 2 226 ? 126.424 139.936 83.748  1.00 12.14  ? 215 GLU B N     1 
ATOM   3163 C CA    . GLU B 2 226 ? 126.538 141.120 82.903  1.00 14.11  ? 215 GLU B CA    1 
ATOM   3164 C C     . GLU B 2 226 ? 127.493 142.145 83.507  1.00 15.25  ? 215 GLU B C     1 
ATOM   3165 O O     . GLU B 2 226 ? 128.341 142.701 82.801  1.00 15.40  ? 215 GLU B O     1 
ATOM   3166 C CB    . GLU B 2 226 ? 125.157 141.729 82.673  1.00 15.28  ? 215 GLU B CB    1 
ATOM   3167 N N     . GLY B 2 227 ? 127.372 142.407 84.805  1.00 17.28  ? 216 GLY B N     1 
ATOM   3168 C CA    . GLY B 2 227 ? 128.335 143.228 85.507  1.00 16.05  ? 216 GLY B CA    1 
ATOM   3169 C C     . GLY B 2 227 ? 128.000 144.697 85.649  1.00 14.38  ? 216 GLY B C     1 
ATOM   3170 O O     . GLY B 2 227 ? 128.882 145.475 86.032  1.00 16.63  ? 216 GLY B O     1 
ATOM   3171 N N     . MET B 2 228 ? 126.768 145.108 85.362  1.00 10.71  ? 217 MET B N     1 
ATOM   3172 C CA    . MET B 2 228 ? 126.371 146.498 85.529  1.00 12.72  ? 217 MET B CA    1 
ATOM   3173 C C     . MET B 2 228 ? 125.245 146.598 86.550  1.00 11.89  ? 217 MET B C     1 
ATOM   3174 O O     . MET B 2 228 ? 124.548 145.622 86.840  1.00 11.04  ? 217 MET B O     1 
ATOM   3175 C CB    . MET B 2 228 ? 125.928 147.134 84.203  1.00 13.89  ? 217 MET B CB    1 
ATOM   3176 C CG    . MET B 2 228 ? 124.532 146.748 83.744  1.00 15.59  ? 217 MET B CG    1 
ATOM   3177 S SD    . MET B 2 228 ? 124.427 145.067 83.117  1.00 29.05  ? 217 MET B SD    1 
ATOM   3178 C CE    . MET B 2 228 ? 125.337 145.226 81.582  1.00 16.62  ? 217 MET B CE    1 
ATOM   3179 N N     . CYS B 2 229 ? 125.080 147.800 87.099  1.00 12.20  ? 218 CYS B N     1 
ATOM   3180 C CA    . CYS B 2 229 ? 124.056 148.051 88.107  1.00 9.70   ? 218 CYS B CA    1 
ATOM   3181 C C     . CYS B 2 229 ? 122.683 148.013 87.452  1.00 10.91  ? 218 CYS B C     1 
ATOM   3182 O O     . CYS B 2 229 ? 122.301 148.946 86.739  1.00 13.96  ? 218 CYS B O     1 
ATOM   3183 C CB    . CYS B 2 229 ? 124.303 149.394 88.786  1.00 10.18  ? 218 CYS B CB    1 
ATOM   3184 S SG    . CYS B 2 229 ? 122.964 149.949 89.860  1.00 11.01  ? 218 CYS B SG    1 
ATOM   3185 N N     . ARG B 2 230 ? 121.941 146.931 87.689  1.00 9.19   ? 219 ARG B N     1 
ATOM   3186 C CA    . ARG B 2 230 ? 120.610 146.811 87.105  1.00 8.50   ? 219 ARG B CA    1 
ATOM   3187 C C     . ARG B 2 230 ? 119.659 147.851 87.682  1.00 9.90   ? 219 ARG B C     1 
ATOM   3188 O O     . ARG B 2 230 ? 118.938 148.524 86.938  1.00 12.76  ? 219 ARG B O     1 
ATOM   3189 C CB    . ARG B 2 230 ? 120.062 145.399 87.322  1.00 9.87   ? 219 ARG B CB    1 
ATOM   3190 C CG    . ARG B 2 230 ? 120.816 144.312 86.574  1.00 13.16  ? 219 ARG B CG    1 
ATOM   3191 C CD    . ARG B 2 230 ? 121.216 144.771 85.180  1.00 13.16  ? 219 ARG B CD    1 
ATOM   3192 N NE    . ARG B 2 230 ? 120.171 144.513 84.195  1.00 15.33  ? 219 ARG B NE    1 
ATOM   3193 C CZ    . ARG B 2 230 ? 119.903 143.322 83.678  1.00 16.83  ? 219 ARG B CZ    1 
ATOM   3194 N NH1   . ARG B 2 230 ? 120.590 142.246 84.024  1.00 14.11  ? 219 ARG B NH1   1 
ATOM   3195 N NH2   . ARG B 2 230 ? 118.920 143.208 82.789  1.00 14.62  ? 219 ARG B NH2   1 
ATOM   3196 N N     . GLN B 2 231 ? 119.647 148.004 89.005  1.00 7.40   ? 220 GLN B N     1 
ATOM   3197 C CA    . GLN B 2 231 ? 118.689 148.905 89.638  1.00 3.28   ? 220 GLN B CA    1 
ATOM   3198 C C     . GLN B 2 231 ? 119.323 149.606 90.831  1.00 3.42   ? 220 GLN B C     1 
ATOM   3199 O O     . GLN B 2 231 ? 120.306 149.137 91.403  1.00 6.64   ? 220 GLN B O     1 
ATOM   3200 C CB    . GLN B 2 231 ? 117.420 148.164 90.086  1.00 8.37   ? 220 GLN B CB    1 
ATOM   3201 C CG    . GLN B 2 231 ? 116.560 147.634 88.947  1.00 8.63   ? 220 GLN B CG    1 
ATOM   3202 C CD    . GLN B 2 231 ? 115.221 147.104 89.420  1.00 9.01   ? 220 GLN B CD    1 
ATOM   3203 O OE1   . GLN B 2 231 ? 114.596 147.674 90.313  1.00 9.42   ? 220 GLN B OE1   1 
ATOM   3204 N NE2   . GLN B 2 231 ? 114.776 146.005 88.823  1.00 8.50   ? 220 GLN B NE2   1 
ATOM   3205 N N     . THR B 2 232 ? 118.731 150.738 91.208  1.00 6.79   ? 221 THR B N     1 
ATOM   3206 C CA    . THR B 2 232 ? 119.150 151.498 92.379  1.00 5.32   ? 221 THR B CA    1 
ATOM   3207 C C     . THR B 2 232 ? 117.925 151.829 93.219  1.00 6.25   ? 221 THR B C     1 
ATOM   3208 O O     . THR B 2 232 ? 116.913 152.296 92.687  1.00 7.31   ? 221 THR B O     1 
ATOM   3209 C CB    . THR B 2 232 ? 119.883 152.784 91.981  1.00 8.25   ? 221 THR B CB    1 
ATOM   3210 O OG1   . THR B 2 232 ? 120.960 152.465 91.091  1.00 10.96  ? 221 THR B OG1   1 
ATOM   3211 C CG2   . THR B 2 232 ? 120.446 153.478 93.209  1.00 3.46   ? 221 THR B CG2   1 
ATOM   3212 N N     . PHE B 2 233 ? 118.019 151.586 94.524  1.00 6.56   ? 222 PHE B N     1 
ATOM   3213 C CA    . PHE B 2 233 ? 116.922 151.787 95.461  1.00 6.34   ? 222 PHE B CA    1 
ATOM   3214 C C     . PHE B 2 233 ? 117.364 152.749 96.553  1.00 4.33   ? 222 PHE B C     1 
ATOM   3215 O O     . PHE B 2 233 ? 118.452 152.594 97.120  1.00 7.05   ? 222 PHE B O     1 
ATOM   3216 C CB    . PHE B 2 233 ? 116.477 150.459 96.084  1.00 4.49   ? 222 PHE B CB    1 
ATOM   3217 C CG    . PHE B 2 233 ? 116.186 149.381 95.080  1.00 5.81   ? 222 PHE B CG    1 
ATOM   3218 C CD1   . PHE B 2 233 ? 117.203 148.580 94.588  1.00 3.86   ? 222 PHE B CD1   1 
ATOM   3219 C CD2   . PHE B 2 233 ? 114.895 149.164 94.633  1.00 4.01   ? 222 PHE B CD2   1 
ATOM   3220 C CE1   . PHE B 2 233 ? 116.939 147.589 93.667  1.00 3.43   ? 222 PHE B CE1   1 
ATOM   3221 C CE2   . PHE B 2 233 ? 114.624 148.173 93.712  1.00 8.71   ? 222 PHE B CE2   1 
ATOM   3222 C CZ    . PHE B 2 233 ? 115.648 147.385 93.229  1.00 8.12   ? 222 PHE B CZ    1 
ATOM   3223 N N     . THR B 2 234 ? 116.519 153.732 96.848  1.00 6.77   ? 223 THR B N     1 
ATOM   3224 C CA    . THR B 2 234 ? 116.777 154.712 97.890  1.00 7.41   ? 223 THR B CA    1 
ATOM   3225 C C     . THR B 2 234 ? 115.570 154.791 98.815  1.00 7.48   ? 223 THR B C     1 
ATOM   3226 O O     . THR B 2 234 ? 114.520 154.198 98.559  1.00 7.95   ? 223 THR B O     1 
ATOM   3227 C CB    . THR B 2 234 ? 117.086 156.096 97.301  1.00 8.03   ? 223 THR B CB    1 
ATOM   3228 O OG1   . THR B 2 234 ? 116.140 156.402 96.269  1.00 9.88   ? 223 THR B OG1   1 
ATOM   3229 C CG2   . THR B 2 234 ? 118.490 156.128 96.720  1.00 8.73   ? 223 THR B CG2   1 
ATOM   3230 N N     . GLY B 2 235 ? 115.731 155.539 99.903  1.00 8.13   ? 224 GLY B N     1 
ATOM   3231 C CA    . GLY B 2 235 ? 114.664 155.705 100.869 1.00 4.29   ? 224 GLY B CA    1 
ATOM   3232 C C     . GLY B 2 235 ? 115.150 155.721 102.303 1.00 5.58   ? 224 GLY B C     1 
ATOM   3233 O O     . GLY B 2 235 ? 114.515 156.329 103.170 1.00 9.02   ? 224 GLY B O     1 
ATOM   3234 N N     . HIS B 2 236 ? 116.275 155.063 102.567 1.00 3.33   ? 225 HIS B N     1 
ATOM   3235 C CA    . HIS B 2 236 ? 116.849 155.080 103.904 1.00 3.47   ? 225 HIS B CA    1 
ATOM   3236 C C     . HIS B 2 236 ? 117.475 156.438 104.194 1.00 8.10   ? 225 HIS B C     1 
ATOM   3237 O O     . HIS B 2 236 ? 118.020 157.093 103.302 1.00 6.93   ? 225 HIS B O     1 
ATOM   3238 C CB    . HIS B 2 236 ? 117.891 153.974 104.053 1.00 3.50   ? 225 HIS B CB    1 
ATOM   3239 C CG    . HIS B 2 236 ? 117.312 152.648 104.436 1.00 5.32   ? 225 HIS B CG    1 
ATOM   3240 N ND1   . HIS B 2 236 ? 116.620 152.450 105.611 1.00 5.58   ? 225 HIS B ND1   1 
ATOM   3241 C CD2   . HIS B 2 236 ? 117.323 151.453 103.801 1.00 1.65   ? 225 HIS B CD2   1 
ATOM   3242 C CE1   . HIS B 2 236 ? 116.231 151.190 105.683 1.00 5.01   ? 225 HIS B CE1   1 
ATOM   3243 N NE2   . HIS B 2 236 ? 116.644 150.564 104.597 1.00 0.60   ? 225 HIS B NE2   1 
ATOM   3244 N N     . GLU B 2 237 ? 117.389 156.862 105.451 1.00 11.71  ? 226 GLU B N     1 
ATOM   3245 C CA    . GLU B 2 237 ? 117.892 158.164 105.864 1.00 8.78   ? 226 GLU B CA    1 
ATOM   3246 C C     . GLU B 2 237 ? 119.323 158.121 106.385 1.00 9.10   ? 226 GLU B C     1 
ATOM   3247 O O     . GLU B 2 237 ? 119.879 159.176 106.703 1.00 10.36  ? 226 GLU B O     1 
ATOM   3248 C CB    . GLU B 2 237 ? 116.976 158.766 106.934 1.00 6.54   ? 226 GLU B CB    1 
ATOM   3249 N N     . SER B 2 238 ? 119.933 156.943 106.481 1.00 7.08   ? 227 SER B N     1 
ATOM   3250 C CA    . SER B 2 238 ? 121.291 156.835 106.996 1.00 6.02   ? 227 SER B CA    1 
ATOM   3251 C C     . SER B 2 238 ? 121.968 155.632 106.348 1.00 6.71   ? 227 SER B C     1 
ATOM   3252 O O     . SER B 2 238 ? 121.484 155.085 105.352 1.00 9.86   ? 227 SER B O     1 
ATOM   3253 C CB    . SER B 2 238 ? 121.284 156.742 108.526 1.00 7.60   ? 227 SER B CB    1 
ATOM   3254 O OG    . SER B 2 238 ? 122.604 156.660 109.031 1.00 10.46  ? 227 SER B OG    1 
ATOM   3255 N N     . ASP B 2 239 ? 123.096 155.221 106.923 1.00 6.47   ? 228 ASP B N     1 
ATOM   3256 C CA    . ASP B 2 239 ? 123.912 154.164 106.339 1.00 5.72   ? 228 ASP B CA    1 
ATOM   3257 C C     . ASP B 2 239 ? 123.180 152.829 106.391 1.00 3.74   ? 228 ASP B C     1 
ATOM   3258 O O     . ASP B 2 239 ? 122.639 152.449 107.433 1.00 7.33   ? 228 ASP B O     1 
ATOM   3259 C CB    . ASP B 2 239 ? 125.240 154.056 107.085 1.00 7.58   ? 228 ASP B CB    1 
ATOM   3260 C CG    . ASP B 2 239 ? 126.034 155.345 107.053 1.00 11.15  ? 228 ASP B CG    1 
ATOM   3261 O OD1   . ASP B 2 239 ? 125.891 156.113 106.082 1.00 10.47  ? 228 ASP B OD1   1 
ATOM   3262 O OD2   . ASP B 2 239 ? 126.807 155.591 108.003 1.00 11.94  ? 228 ASP B OD2   1 
ATOM   3263 N N     . ILE B 2 240 ? 123.177 152.111 105.273 1.00 3.76   ? 229 ILE B N     1 
ATOM   3264 C CA    . ILE B 2 240 ? 122.581 150.780 105.201 1.00 5.72   ? 229 ILE B CA    1 
ATOM   3265 C C     . ILE B 2 240 ? 123.639 149.761 105.602 1.00 4.10   ? 229 ILE B C     1 
ATOM   3266 O O     . ILE B 2 240 ? 124.672 149.633 104.937 1.00 6.31   ? 229 ILE B O     1 
ATOM   3267 C CB    . ILE B 2 240 ? 122.038 150.485 103.796 1.00 3.62   ? 229 ILE B CB    1 
ATOM   3268 C CG1   . ILE B 2 240 ? 120.921 151.465 103.435 1.00 1.82   ? 229 ILE B CG1   1 
ATOM   3269 C CG2   . ILE B 2 240 ? 121.537 149.053 103.711 1.00 4.09   ? 229 ILE B CG2   1 
ATOM   3270 C CD1   . ILE B 2 240 ? 120.385 151.281 102.037 1.00 2.32   ? 229 ILE B CD1   1 
ATOM   3271 N N     . ASN B 2 241 ? 123.383 149.034 106.688 1.00 0.49   ? 230 ASN B N     1 
ATOM   3272 C CA    . ASN B 2 241 ? 124.351 148.089 107.227 1.00 1.22   ? 230 ASN B CA    1 
ATOM   3273 C C     . ASN B 2 241 ? 124.047 146.643 106.871 1.00 3.90   ? 230 ASN B C     1 
ATOM   3274 O O     . ASN B 2 241 ? 124.967 145.819 106.844 1.00 1.84   ? 230 ASN B O     1 
ATOM   3275 C CB    . ASN B 2 241 ? 124.423 148.218 108.751 1.00 3.81   ? 230 ASN B CB    1 
ATOM   3276 C CG    . ASN B 2 241 ? 124.706 149.634 109.202 1.00 6.59   ? 230 ASN B CG    1 
ATOM   3277 O OD1   . ASN B 2 241 ? 125.634 150.280 108.715 1.00 10.37  ? 230 ASN B OD1   1 
ATOM   3278 N ND2   . ASN B 2 241 ? 123.903 150.128 110.135 1.00 5.44   ? 230 ASN B ND2   1 
ATOM   3279 N N     . ALA B 2 242 ? 122.787 146.313 106.602 1.00 8.57   ? 231 ALA B N     1 
ATOM   3280 C CA    . ALA B 2 242 ? 122.382 144.943 106.334 1.00 1.73   ? 231 ALA B CA    1 
ATOM   3281 C C     . ALA B 2 242 ? 121.452 144.896 105.131 1.00 1.92   ? 231 ALA B C     1 
ATOM   3282 O O     . ALA B 2 242 ? 120.746 145.861 104.831 1.00 1.94   ? 231 ALA B O     1 
ATOM   3283 C CB    . ALA B 2 242 ? 121.691 144.321 107.548 1.00 0.00   ? 231 ALA B CB    1 
ATOM   3284 N N     . ILE B 2 243 ? 121.460 143.752 104.447 1.00 0.97   ? 232 ILE B N     1 
ATOM   3285 C CA    . ILE B 2 243 ? 120.621 143.532 103.277 1.00 0.00   ? 232 ILE B CA    1 
ATOM   3286 C C     . ILE B 2 243 ? 120.363 142.037 103.158 1.00 3.71   ? 232 ILE B C     1 
ATOM   3287 O O     . ILE B 2 243 ? 121.185 141.214 103.570 1.00 5.83   ? 232 ILE B O     1 
ATOM   3288 C CB    . ILE B 2 243 ? 121.269 144.113 101.995 1.00 0.00   ? 232 ILE B CB    1 
ATOM   3289 C CG1   . ILE B 2 243 ? 120.207 144.423 100.941 1.00 1.59   ? 232 ILE B CG1   1 
ATOM   3290 C CG2   . ILE B 2 243 ? 122.322 143.175 101.436 1.00 0.00   ? 232 ILE B CG2   1 
ATOM   3291 C CD1   . ILE B 2 243 ? 120.640 145.467 99.940  1.00 1.40   ? 232 ILE B CD1   1 
ATOM   3292 N N     . CYS B 2 244 ? 119.199 141.686 102.612 1.00 2.76   ? 233 CYS B N     1 
ATOM   3293 C CA    . CYS B 2 244 ? 118.817 140.284 102.489 1.00 0.00   ? 233 CYS B CA    1 
ATOM   3294 C C     . CYS B 2 244 ? 117.715 140.150 101.451 1.00 1.99   ? 233 CYS B C     1 
ATOM   3295 O O     . CYS B 2 244 ? 116.701 140.847 101.534 1.00 6.46   ? 233 CYS B O     1 
ATOM   3296 C CB    . CYS B 2 244 ? 118.348 139.721 103.835 1.00 0.00   ? 233 CYS B CB    1 
ATOM   3297 S SG    . CYS B 2 244 ? 118.242 137.919 103.893 1.00 13.40  ? 233 CYS B SG    1 
ATOM   3298 N N     . PHE B 2 245 ? 117.913 139.255 100.485 1.00 2.98   ? 234 PHE B N     1 
ATOM   3299 C CA    . PHE B 2 245 ? 116.865 138.952 99.520  1.00 1.37   ? 234 PHE B CA    1 
ATOM   3300 C C     . PHE B 2 245 ? 115.686 138.251 100.179 1.00 1.86   ? 234 PHE B C     1 
ATOM   3301 O O     . PHE B 2 245 ? 115.849 137.464 101.116 1.00 5.28   ? 234 PHE B O     1 
ATOM   3302 C CB    . PHE B 2 245 ? 117.395 138.069 98.390  1.00 1.81   ? 234 PHE B CB    1 
ATOM   3303 C CG    . PHE B 2 245 ? 117.991 138.828 97.244  1.00 1.38   ? 234 PHE B CG    1 
ATOM   3304 C CD1   . PHE B 2 245 ? 117.170 139.423 96.301  1.00 0.00   ? 234 PHE B CD1   1 
ATOM   3305 C CD2   . PHE B 2 245 ? 119.359 138.910 97.078  1.00 0.73   ? 234 PHE B CD2   1 
ATOM   3306 C CE1   . PHE B 2 245 ? 117.702 140.110 95.232  1.00 1.71   ? 234 PHE B CE1   1 
ATOM   3307 C CE2   . PHE B 2 245 ? 119.897 139.593 96.006  1.00 1.79   ? 234 PHE B CE2   1 
ATOM   3308 C CZ    . PHE B 2 245 ? 119.068 140.195 95.084  1.00 2.63   ? 234 PHE B CZ    1 
ATOM   3309 N N     . PHE B 2 246 ? 114.492 138.542 99.676  1.00 2.82   ? 235 PHE B N     1 
ATOM   3310 C CA    . PHE B 2 246 ? 113.329 137.744 100.007 1.00 1.69   ? 235 PHE B CA    1 
ATOM   3311 C C     . PHE B 2 246 ? 113.492 136.345 99.410  1.00 9.08   ? 235 PHE B C     1 
ATOM   3312 O O     . PHE B 2 246 ? 114.130 136.182 98.367  1.00 11.90  ? 235 PHE B O     1 
ATOM   3313 C CB    . PHE B 2 246 ? 112.063 138.408 99.469  1.00 2.38   ? 235 PHE B CB    1 
ATOM   3314 C CG    . PHE B 2 246 ? 110.793 137.845 100.032 1.00 7.50   ? 235 PHE B CG    1 
ATOM   3315 C CD1   . PHE B 2 246 ? 110.300 138.295 101.242 1.00 4.69   ? 235 PHE B CD1   1 
ATOM   3316 C CD2   . PHE B 2 246 ? 110.094 136.864 99.354  1.00 8.89   ? 235 PHE B CD2   1 
ATOM   3317 C CE1   . PHE B 2 246 ? 109.136 137.778 101.763 1.00 3.52   ? 235 PHE B CE1   1 
ATOM   3318 C CE2   . PHE B 2 246 ? 108.931 136.339 99.873  1.00 7.49   ? 235 PHE B CE2   1 
ATOM   3319 C CZ    . PHE B 2 246 ? 108.452 136.795 101.081 1.00 7.84   ? 235 PHE B CZ    1 
ATOM   3320 N N     . PRO B 2 247 ? 112.942 135.316 100.062 1.00 8.62   ? 236 PRO B N     1 
ATOM   3321 C CA    . PRO B 2 247 ? 113.080 133.954 99.517  1.00 5.78   ? 236 PRO B CA    1 
ATOM   3322 C C     . PRO B 2 247 ? 112.567 133.807 98.095  1.00 9.00   ? 236 PRO B C     1 
ATOM   3323 O O     . PRO B 2 247 ? 113.114 133.002 97.331  1.00 9.43   ? 236 PRO B O     1 
ATOM   3324 C CB    . PRO B 2 247 ? 112.266 133.106 100.502 1.00 6.57   ? 236 PRO B CB    1 
ATOM   3325 C CG    . PRO B 2 247 ? 112.366 133.848 101.784 1.00 7.12   ? 236 PRO B CG    1 
ATOM   3326 C CD    . PRO B 2 247 ? 112.384 135.307 101.427 1.00 6.03   ? 236 PRO B CD    1 
ATOM   3327 N N     . ASN B 2 248 ? 111.533 134.559 97.714  1.00 9.43   ? 237 ASN B N     1 
ATOM   3328 C CA    . ASN B 2 248 ? 111.048 134.522 96.340  1.00 9.13   ? 237 ASN B CA    1 
ATOM   3329 C C     . ASN B 2 248 ? 112.079 135.047 95.350  1.00 11.75  ? 237 ASN B C     1 
ATOM   3330 O O     . ASN B 2 248 ? 112.052 134.658 94.177  1.00 11.09  ? 237 ASN B O     1 
ATOM   3331 C CB    . ASN B 2 248 ? 109.753 135.329 96.224  1.00 9.24   ? 237 ASN B CB    1 
ATOM   3332 C CG    . ASN B 2 248 ? 109.078 135.163 94.879  1.00 11.99  ? 237 ASN B CG    1 
ATOM   3333 O OD1   . ASN B 2 248 ? 109.252 134.148 94.204  1.00 12.32  ? 237 ASN B OD1   1 
ATOM   3334 N ND2   . ASN B 2 248 ? 108.297 136.161 94.483  1.00 10.47  ? 237 ASN B ND2   1 
ATOM   3335 N N     . GLY B 2 249 ? 112.988 135.913 95.792  1.00 13.69  ? 238 GLY B N     1 
ATOM   3336 C CA    . GLY B 2 249 ? 113.988 136.492 94.923  1.00 7.30   ? 238 GLY B CA    1 
ATOM   3337 C C     . GLY B 2 249 ? 113.559 137.746 94.195  1.00 11.24  ? 238 GLY B C     1 
ATOM   3338 O O     . GLY B 2 249 ? 114.377 138.337 93.478  1.00 13.86  ? 238 GLY B O     1 
ATOM   3339 N N     . ASN B 2 250 ? 112.307 138.171 94.350  1.00 9.15   ? 239 ASN B N     1 
ATOM   3340 C CA    . ASN B 2 250 ? 111.797 139.371 93.703  1.00 10.07  ? 239 ASN B CA    1 
ATOM   3341 C C     . ASN B 2 250 ? 111.737 140.565 94.645  1.00 10.29  ? 239 ASN B C     1 
ATOM   3342 O O     . ASN B 2 250 ? 111.169 141.600 94.283  1.00 11.71  ? 239 ASN B O     1 
ATOM   3343 C CB    . ASN B 2 250 ? 110.412 139.101 93.112  1.00 12.64  ? 239 ASN B CB    1 
ATOM   3344 C CG    . ASN B 2 250 ? 110.458 138.159 91.927  1.00 12.34  ? 239 ASN B CG    1 
ATOM   3345 O OD1   . ASN B 2 250 ? 111.372 138.222 91.106  1.00 11.76  ? 239 ASN B OD1   1 
ATOM   3346 N ND2   . ASN B 2 250 ? 109.469 137.280 91.831  1.00 12.73  ? 239 ASN B ND2   1 
ATOM   3347 N N     . ALA B 2 251 ? 112.306 140.446 95.841  1.00 7.23   ? 240 ALA B N     1 
ATOM   3348 C CA    . ALA B 2 251 ? 112.281 141.524 96.820  1.00 4.79   ? 240 ALA B CA    1 
ATOM   3349 C C     . ALA B 2 251 ? 113.465 141.349 97.759  1.00 2.77   ? 240 ALA B C     1 
ATOM   3350 O O     . ALA B 2 251 ? 114.096 140.291 97.805  1.00 9.69   ? 240 ALA B O     1 
ATOM   3351 C CB    . ALA B 2 251 ? 110.960 141.545 97.595  1.00 7.04   ? 240 ALA B CB    1 
ATOM   3352 N N     . PHE B 2 252 ? 113.764 142.410 98.503  1.00 4.04   ? 241 PHE B N     1 
ATOM   3353 C CA    . PHE B 2 252 ? 114.851 142.360 99.471  1.00 1.94   ? 241 PHE B CA    1 
ATOM   3354 C C     . PHE B 2 252 ? 114.606 143.384 100.569 1.00 1.35   ? 241 PHE B C     1 
ATOM   3355 O O     . PHE B 2 252 ? 113.968 144.414 100.346 1.00 4.92   ? 241 PHE B O     1 
ATOM   3356 C CB    . PHE B 2 252 ? 116.212 142.601 98.804  1.00 0.00   ? 241 PHE B CB    1 
ATOM   3357 C CG    . PHE B 2 252 ? 116.393 143.994 98.274  1.00 3.03   ? 241 PHE B CG    1 
ATOM   3358 C CD1   . PHE B 2 252 ? 115.892 144.345 97.033  1.00 4.21   ? 241 PHE B CD1   1 
ATOM   3359 C CD2   . PHE B 2 252 ? 117.070 144.950 99.011  1.00 2.11   ? 241 PHE B CD2   1 
ATOM   3360 C CE1   . PHE B 2 252 ? 116.057 145.620 96.542  1.00 2.33   ? 241 PHE B CE1   1 
ATOM   3361 C CE2   . PHE B 2 252 ? 117.236 146.227 98.522  1.00 1.37   ? 241 PHE B CE2   1 
ATOM   3362 C CZ    . PHE B 2 252 ? 116.731 146.562 97.288  1.00 0.12   ? 241 PHE B CZ    1 
ATOM   3363 N N     . ALA B 2 253 ? 115.142 143.100 101.751 1.00 1.45   ? 242 ALA B N     1 
ATOM   3364 C CA    . ALA B 2 253 ? 115.005 143.971 102.908 1.00 0.73   ? 242 ALA B CA    1 
ATOM   3365 C C     . ALA B 2 253 ? 116.350 144.588 103.263 1.00 2.47   ? 242 ALA B C     1 
ATOM   3366 O O     . ALA B 2 253 ? 117.393 143.936 103.151 1.00 1.50   ? 242 ALA B O     1 
ATOM   3367 C CB    . ALA B 2 253 ? 114.449 143.209 104.113 1.00 1.53   ? 242 ALA B CB    1 
ATOM   3368 N N     . THR B 2 254 ? 116.319 145.848 103.688 1.00 6.16   ? 243 THR B N     1 
ATOM   3369 C CA    . THR B 2 254 ? 117.510 146.593 104.067 1.00 2.25   ? 243 THR B CA    1 
ATOM   3370 C C     . THR B 2 254 ? 117.345 147.123 105.481 1.00 1.49   ? 243 THR B C     1 
ATOM   3371 O O     . THR B 2 254 ? 116.313 147.720 105.807 1.00 8.34   ? 243 THR B O     1 
ATOM   3372 C CB    . THR B 2 254 ? 117.767 147.764 103.114 1.00 4.75   ? 243 THR B CB    1 
ATOM   3373 O OG1   . THR B 2 254 ? 116.599 148.590 103.048 1.00 7.37   ? 243 THR B OG1   1 
ATOM   3374 C CG2   . THR B 2 254 ? 118.094 147.264 101.728 1.00 3.35   ? 243 THR B CG2   1 
ATOM   3375 N N     . GLY B 2 255 ? 118.358 146.909 106.310 1.00 2.86   ? 244 GLY B N     1 
ATOM   3376 C CA    . GLY B 2 255 ? 118.440 147.515 107.631 1.00 3.33   ? 244 GLY B CA    1 
ATOM   3377 C C     . GLY B 2 255 ? 119.490 148.611 107.610 1.00 4.96   ? 244 GLY B C     1 
ATOM   3378 O O     . GLY B 2 255 ? 120.581 148.423 107.068 1.00 9.96   ? 244 GLY B O     1 
ATOM   3379 N N     . SER B 2 256 ? 119.156 149.754 108.196 1.00 5.28   ? 245 SER B N     1 
ATOM   3380 C CA    . SER B 2 256 ? 120.015 150.925 108.128 1.00 7.01   ? 245 SER B CA    1 
ATOM   3381 C C     . SER B 2 256 ? 120.390 151.399 109.526 1.00 8.17   ? 245 SER B C     1 
ATOM   3382 O O     . SER B 2 256 ? 119.917 150.876 110.538 1.00 6.18   ? 245 SER B O     1 
ATOM   3383 C CB    . SER B 2 256 ? 119.341 152.059 107.349 1.00 6.09   ? 245 SER B CB    1 
ATOM   3384 O OG    . SER B 2 256 ? 120.156 153.217 107.330 1.00 8.21   ? 245 SER B OG    1 
ATOM   3385 N N     . ASP B 2 257 ? 121.267 152.406 109.564 1.00 10.51  ? 246 ASP B N     1 
ATOM   3386 C CA    . ASP B 2 257 ? 121.693 152.986 110.832 1.00 6.33   ? 246 ASP B CA    1 
ATOM   3387 C C     . ASP B 2 257 ? 120.555 153.691 111.554 1.00 9.09   ? 246 ASP B C     1 
ATOM   3388 O O     . ASP B 2 257 ? 120.655 153.925 112.763 1.00 11.02  ? 246 ASP B O     1 
ATOM   3389 C CB    . ASP B 2 257 ? 122.849 153.961 110.605 1.00 3.28   ? 246 ASP B CB    1 
ATOM   3390 C CG    . ASP B 2 257 ? 124.203 153.322 110.831 1.00 9.93   ? 246 ASP B CG    1 
ATOM   3391 O OD1   . ASP B 2 257 ? 124.244 152.141 111.233 1.00 14.57  ? 246 ASP B OD1   1 
ATOM   3392 O OD2   . ASP B 2 257 ? 125.226 154.001 110.607 1.00 10.87  ? 246 ASP B OD2   1 
ATOM   3393 N N     . ASP B 2 258 ? 119.486 154.046 110.847 1.00 6.42   ? 247 ASP B N     1 
ATOM   3394 C CA    . ASP B 2 258 ? 118.287 154.530 111.506 1.00 9.30   ? 247 ASP B CA    1 
ATOM   3395 C C     . ASP B 2 258 ? 117.506 153.347 112.078 1.00 11.75  ? 247 ASP B C     1 
ATOM   3396 O O     . ASP B 2 258 ? 117.927 152.190 111.996 1.00 16.14  ? 247 ASP B O     1 
ATOM   3397 C CB    . ASP B 2 258 ? 117.444 155.363 110.540 1.00 7.37   ? 247 ASP B CB    1 
ATOM   3398 C CG    . ASP B 2 258 ? 117.220 154.675 109.205 1.00 9.69   ? 247 ASP B CG    1 
ATOM   3399 O OD1   . ASP B 2 258 ? 117.144 153.430 109.170 1.00 13.60  ? 247 ASP B OD1   1 
ATOM   3400 O OD2   . ASP B 2 258 ? 117.116 155.385 108.184 1.00 8.17   ? 247 ASP B OD2   1 
ATOM   3401 N N     . ALA B 2 259 ? 116.351 153.633 112.665 1.00 5.10   ? 248 ALA B N     1 
ATOM   3402 C CA    . ALA B 2 259 ? 115.546 152.607 113.310 1.00 10.83  ? 248 ALA B CA    1 
ATOM   3403 C C     . ALA B 2 259 ? 114.563 151.937 112.361 1.00 15.91  ? 248 ALA B C     1 
ATOM   3404 O O     . ALA B 2 259 ? 113.565 151.373 112.822 1.00 18.02  ? 248 ALA B O     1 
ATOM   3405 C CB    . ALA B 2 259 ? 114.792 153.203 114.500 1.00 17.27  ? 248 ALA B CB    1 
ATOM   3406 N N     . THR B 2 260 ? 114.813 151.984 111.056 1.00 7.59   ? 249 THR B N     1 
ATOM   3407 C CA    . THR B 2 260 ? 113.870 151.492 110.064 1.00 6.89   ? 249 THR B CA    1 
ATOM   3408 C C     . THR B 2 260 ? 114.491 150.389 109.217 1.00 7.17   ? 249 THR B C     1 
ATOM   3409 O O     . THR B 2 260 ? 115.617 150.526 108.728 1.00 8.86   ? 249 THR B O     1 
ATOM   3410 C CB    . THR B 2 260 ? 113.399 152.622 109.143 1.00 8.25   ? 249 THR B CB    1 
ATOM   3411 O OG1   . THR B 2 260 ? 114.507 153.106 108.375 1.00 11.42  ? 249 THR B OG1   1 
ATOM   3412 C CG2   . THR B 2 260 ? 112.826 153.770 109.955 1.00 10.73  ? 249 THR B CG2   1 
ATOM   3413 N N     . CYS B 2 261 ? 113.753 149.296 109.056 1.00 10.96  ? 250 CYS B N     1 
ATOM   3414 C CA    . CYS B 2 261 ? 113.979 148.362 107.964 1.00 4.27   ? 250 CYS B CA    1 
ATOM   3415 C C     . CYS B 2 261 ? 113.065 148.740 106.808 1.00 6.50   ? 250 CYS B C     1 
ATOM   3416 O O     . CYS B 2 261 ? 111.983 149.289 107.011 1.00 10.77  ? 250 CYS B O     1 
ATOM   3417 C CB    . CYS B 2 261 ? 113.705 146.920 108.393 1.00 7.56   ? 250 CYS B CB    1 
ATOM   3418 S SG    . CYS B 2 261 ? 114.891 146.210 109.549 1.00 12.97  ? 250 CYS B SG    1 
ATOM   3419 N N     . ARG B 2 262 ? 113.506 148.451 105.590 1.00 2.78   ? 251 ARG B N     1 
ATOM   3420 C CA    . ARG B 2 262 ? 112.704 148.784 104.422 1.00 3.92   ? 251 ARG B CA    1 
ATOM   3421 C C     . ARG B 2 262 ? 112.710 147.630 103.435 1.00 3.19   ? 251 ARG B C     1 
ATOM   3422 O O     . ARG B 2 262 ? 113.760 147.051 103.151 1.00 3.68   ? 251 ARG B O     1 
ATOM   3423 C CB    . ARG B 2 262 ? 113.205 150.066 103.747 1.00 5.06   ? 251 ARG B CB    1 
ATOM   3424 C CG    . ARG B 2 262 ? 112.929 151.316 104.560 1.00 6.63   ? 251 ARG B CG    1 
ATOM   3425 C CD    . ARG B 2 262 ? 113.505 152.555 103.910 1.00 6.26   ? 251 ARG B CD    1 
ATOM   3426 N NE    . ARG B 2 262 ? 113.704 153.620 104.886 1.00 6.17   ? 251 ARG B NE    1 
ATOM   3427 C CZ    . ARG B 2 262 ? 112.858 154.620 105.085 1.00 9.97   ? 251 ARG B CZ    1 
ATOM   3428 N NH1   . ARG B 2 262 ? 111.736 154.725 104.392 1.00 8.37   ? 251 ARG B NH1   1 
ATOM   3429 N NH2   . ARG B 2 262 ? 113.145 155.540 106.002 1.00 10.86  ? 251 ARG B NH2   1 
ATOM   3430 N N     . LEU B 2 263 ? 111.532 147.307 102.912 1.00 3.39   ? 252 LEU B N     1 
ATOM   3431 C CA    . LEU B 2 263 ? 111.370 146.228 101.948 1.00 3.46   ? 252 LEU B CA    1 
ATOM   3432 C C     . LEU B 2 263 ? 111.186 146.827 100.560 1.00 6.22   ? 252 LEU B C     1 
ATOM   3433 O O     . LEU B 2 263 ? 110.277 147.636 100.345 1.00 8.44   ? 252 LEU B O     1 
ATOM   3434 C CB    . LEU B 2 263 ? 110.182 145.342 102.319 1.00 7.66   ? 252 LEU B CB    1 
ATOM   3435 C CG    . LEU B 2 263 ? 109.790 144.249 101.324 1.00 5.98   ? 252 LEU B CG    1 
ATOM   3436 C CD1   . LEU B 2 263 ? 110.685 143.032 101.480 1.00 2.90   ? 252 LEU B CD1   1 
ATOM   3437 C CD2   . LEU B 2 263 ? 108.332 143.870 101.505 1.00 6.49   ? 252 LEU B CD2   1 
ATOM   3438 N N     . PHE B 2 264 ? 112.047 146.433 99.628  1.00 4.03   ? 253 PHE B N     1 
ATOM   3439 C CA    . PHE B 2 264 ? 112.003 146.895 98.252  1.00 4.44   ? 253 PHE B CA    1 
ATOM   3440 C C     . PHE B 2 264 ? 111.666 145.727 97.337  1.00 7.11   ? 253 PHE B C     1 
ATOM   3441 O O     . PHE B 2 264 ? 112.067 144.587 97.587  1.00 8.46   ? 253 PHE B O     1 
ATOM   3442 C CB    . PHE B 2 264 ? 113.340 147.509 97.825  1.00 6.57   ? 253 PHE B CB    1 
ATOM   3443 C CG    . PHE B 2 264 ? 113.779 148.669 98.672  1.00 5.03   ? 253 PHE B CG    1 
ATOM   3444 C CD1   . PHE B 2 264 ? 114.470 148.461 99.852  1.00 2.74   ? 253 PHE B CD1   1 
ATOM   3445 C CD2   . PHE B 2 264 ? 113.516 149.969 98.278  1.00 6.76   ? 253 PHE B CD2   1 
ATOM   3446 C CE1   . PHE B 2 264 ? 114.878 149.525 100.628 1.00 3.68   ? 253 PHE B CE1   1 
ATOM   3447 C CE2   . PHE B 2 264 ? 113.923 151.037 99.050  1.00 8.16   ? 253 PHE B CE2   1 
ATOM   3448 C CZ    . PHE B 2 264 ? 114.605 150.814 100.227 1.00 4.77   ? 253 PHE B CZ    1 
ATOM   3449 N N     . ASP B 2 265 ? 110.924 146.020 96.274  1.00 11.24  ? 254 ASP B N     1 
ATOM   3450 C CA    . ASP B 2 265 ? 110.534 145.022 95.288  1.00 11.11  ? 254 ASP B CA    1 
ATOM   3451 C C     . ASP B 2 265 ? 111.340 145.234 94.015  1.00 11.24  ? 254 ASP B C     1 
ATOM   3452 O O     . ASP B 2 265 ? 111.438 146.361 93.519  1.00 12.48  ? 254 ASP B O     1 
ATOM   3453 C CB    . ASP B 2 265 ? 109.036 145.098 94.989  1.00 11.81  ? 254 ASP B CB    1 
ATOM   3454 C CG    . ASP B 2 265 ? 108.548 143.925 94.163  1.00 17.47  ? 254 ASP B CG    1 
ATOM   3455 O OD1   . ASP B 2 265 ? 108.708 143.958 92.925  1.00 18.29  ? 254 ASP B OD1   1 
ATOM   3456 O OD2   . ASP B 2 265 ? 108.008 142.966 94.753  1.00 15.55  ? 254 ASP B OD2   1 
ATOM   3457 N N     . LEU B 2 266 ? 111.922 144.151 93.498  1.00 7.38   ? 255 LEU B N     1 
ATOM   3458 C CA    . LEU B 2 266 ? 112.739 144.248 92.293  1.00 10.34  ? 255 LEU B CA    1 
ATOM   3459 C C     . LEU B 2 266 ? 111.899 144.652 91.087  1.00 15.00  ? 255 LEU B C     1 
ATOM   3460 O O     . LEU B 2 266 ? 112.261 145.571 90.344  1.00 14.15  ? 255 LEU B O     1 
ATOM   3461 C CB    . LEU B 2 266 ? 113.443 142.917 92.031  1.00 10.53  ? 255 LEU B CB    1 
ATOM   3462 C CG    . LEU B 2 266 ? 114.850 142.727 92.597  1.00 11.13  ? 255 LEU B CG    1 
ATOM   3463 C CD1   . LEU B 2 266 ? 114.832 142.741 94.113  1.00 10.10  ? 255 LEU B CD1   1 
ATOM   3464 C CD2   . LEU B 2 266 ? 115.455 141.432 92.082  1.00 11.35  ? 255 LEU B CD2   1 
ATOM   3465 N N     . ARG B 2 267 ? 110.771 143.971 90.878  1.00 15.07  ? 256 ARG B N     1 
ATOM   3466 C CA    . ARG B 2 267 ? 109.954 144.234 89.698  1.00 13.92  ? 256 ARG B CA    1 
ATOM   3467 C C     . ARG B 2 267 ? 109.256 145.585 89.791  1.00 14.83  ? 256 ARG B C     1 
ATOM   3468 O O     . ARG B 2 267 ? 109.124 146.292 88.786  1.00 16.78  ? 256 ARG B O     1 
ATOM   3469 C CB    . ARG B 2 267 ? 108.942 143.105 89.508  1.00 14.44  ? 256 ARG B CB    1 
ATOM   3470 C CG    . ARG B 2 267 ? 109.574 141.797 89.056  1.00 16.13  ? 256 ARG B CG    1 
ATOM   3471 C CD    . ARG B 2 267 ? 108.865 140.588 89.644  1.00 15.64  ? 256 ARG B CD    1 
ATOM   3472 N NE    . ARG B 2 267 ? 107.535 140.392 89.082  1.00 16.54  ? 256 ARG B NE    1 
ATOM   3473 C CZ    . ARG B 2 267 ? 106.476 140.008 89.782  1.00 16.96  ? 256 ARG B CZ    1 
ATOM   3474 N NH1   . ARG B 2 267 ? 106.554 139.776 91.082  1.00 15.32  ? 256 ARG B NH1   1 
ATOM   3475 N NH2   . ARG B 2 267 ? 105.310 139.853 89.162  1.00 15.98  ? 256 ARG B NH2   1 
ATOM   3476 N N     . ALA B 2 268 ? 108.800 145.961 90.987  1.00 13.79  ? 257 ALA B N     1 
ATOM   3477 C CA    . ALA B 2 268 ? 108.182 147.267 91.174  1.00 11.72  ? 257 ALA B CA    1 
ATOM   3478 C C     . ALA B 2 268 ? 109.203 148.391 91.271  1.00 14.37  ? 257 ALA B C     1 
ATOM   3479 O O     . ALA B 2 268 ? 108.840 149.554 91.064  1.00 15.09  ? 257 ALA B O     1 
ATOM   3480 C CB    . ALA B 2 268 ? 107.305 147.262 92.428  1.00 11.92  ? 257 ALA B CB    1 
ATOM   3481 N N     . ASP B 2 269 ? 110.463 148.068 91.572  1.00 16.11  ? 258 ASP B N     1 
ATOM   3482 C CA    . ASP B 2 269 ? 111.532 149.059 91.706  1.00 13.47  ? 258 ASP B CA    1 
ATOM   3483 C C     . ASP B 2 269 ? 111.160 150.142 92.715  1.00 17.16  ? 258 ASP B C     1 
ATOM   3484 O O     . ASP B 2 269 ? 111.420 151.329 92.511  1.00 20.30  ? 258 ASP B O     1 
ATOM   3485 C CB    . ASP B 2 269 ? 111.885 149.674 90.350  1.00 13.50  ? 258 ASP B CB    1 
ATOM   3486 N N     . GLN B 2 270 ? 110.548 149.726 93.821  1.00 15.97  ? 259 GLN B N     1 
ATOM   3487 C CA    . GLN B 2 270 ? 110.053 150.669 94.812  1.00 13.47  ? 259 GLN B CA    1 
ATOM   3488 C C     . GLN B 2 270 ? 110.114 150.044 96.195  1.00 12.21  ? 259 GLN B C     1 
ATOM   3489 O O     . GLN B 2 270 ? 110.157 148.821 96.349  1.00 17.71  ? 259 GLN B O     1 
ATOM   3490 C CB    . GLN B 2 270 ? 108.617 151.104 94.506  1.00 16.83  ? 259 GLN B CB    1 
ATOM   3491 C CG    . GLN B 2 270 ? 108.511 152.313 93.608  1.00 18.44  ? 259 GLN B CG    1 
ATOM   3492 C CD    . GLN B 2 270 ? 107.087 152.792 93.463  1.00 21.20  ? 259 GLN B CD    1 
ATOM   3493 O OE1   . GLN B 2 270 ? 106.643 153.684 94.186  1.00 23.06  ? 259 GLN B OE1   1 
ATOM   3494 N NE2   . GLN B 2 270 ? 106.359 152.206 92.521  1.00 20.00  ? 259 GLN B NE2   1 
ATOM   3495 N N     . GLU B 2 271 ? 110.112 150.910 97.205  1.00 8.99   ? 260 GLU B N     1 
ATOM   3496 C CA    . GLU B 2 271 ? 110.011 150.461 98.585  1.00 11.64  ? 260 GLU B CA    1 
ATOM   3497 C C     . GLU B 2 271 ? 108.579 150.038 98.885  1.00 14.42  ? 260 GLU B C     1 
ATOM   3498 O O     . GLU B 2 271 ? 107.630 150.769 98.587  1.00 14.87  ? 260 GLU B O     1 
ATOM   3499 C CB    . GLU B 2 271 ? 110.449 151.574 99.533  1.00 11.94  ? 260 GLU B CB    1 
ATOM   3500 C CG    . GLU B 2 271 ? 110.284 151.251 101.003 1.00 12.53  ? 260 GLU B CG    1 
ATOM   3501 C CD    . GLU B 2 271 ? 110.530 152.455 101.887 1.00 16.40  ? 260 GLU B CD    1 
ATOM   3502 O OE1   . GLU B 2 271 ? 111.043 153.472 101.375 1.00 14.83  ? 260 GLU B OE1   1 
ATOM   3503 O OE2   . GLU B 2 271 ? 110.206 152.389 103.091 1.00 19.15  ? 260 GLU B OE2   1 
ATOM   3504 N N     . LEU B 2 272 ? 108.422 148.854 99.475  1.00 11.68  ? 261 LEU B N     1 
ATOM   3505 C CA    . LEU B 2 272 ? 107.095 148.311 99.745  1.00 8.36   ? 261 LEU B CA    1 
ATOM   3506 C C     . LEU B 2 272 ? 106.592 148.712 101.129 1.00 10.14  ? 261 LEU B C     1 
ATOM   3507 O O     . LEU B 2 272 ? 105.530 149.329 101.255 1.00 15.47  ? 261 LEU B O     1 
ATOM   3508 C CB    . LEU B 2 272 ? 107.111 146.786 99.596  1.00 11.39  ? 261 LEU B CB    1 
ATOM   3509 C CG    . LEU B 2 272 ? 107.197 146.250 98.166  1.00 10.44  ? 261 LEU B CG    1 
ATOM   3510 C CD1   . LEU B 2 272 ? 106.933 144.754 98.137  1.00 10.36  ? 261 LEU B CD1   1 
ATOM   3511 C CD2   . LEU B 2 272 ? 106.227 146.985 97.256  1.00 9.61   ? 261 LEU B CD2   1 
ATOM   3512 N N     . MET B 2 273 ? 107.341 148.369 102.175 1.00 13.68  ? 262 MET B N     1 
ATOM   3513 C CA    . MET B 2 273 ? 106.935 148.672 103.538 1.00 16.70  ? 262 MET B CA    1 
ATOM   3514 C C     . MET B 2 273 ? 108.142 149.105 104.355 1.00 13.57  ? 262 MET B C     1 
ATOM   3515 O O     . MET B 2 273 ? 109.292 148.812 104.017 1.00 11.09  ? 262 MET B O     1 
ATOM   3516 C CB    . MET B 2 273 ? 106.257 147.473 104.217 1.00 12.37  ? 262 MET B CB    1 
ATOM   3517 C CG    . MET B 2 273 ? 104.914 147.097 103.622 1.00 17.04  ? 262 MET B CG    1 
ATOM   3518 S SD    . MET B 2 273 ? 104.029 145.885 104.618 1.00 31.83  ? 262 MET B SD    1 
ATOM   3519 C CE    . MET B 2 273 ? 103.305 146.946 105.860 1.00 18.47  ? 262 MET B CE    1 
ATOM   3520 N N     . THR B 2 274 ? 107.857 149.819 105.440 1.00 13.51  ? 263 THR B N     1 
ATOM   3521 C CA    . THR B 2 274 ? 108.861 150.245 106.403 1.00 9.62   ? 263 THR B CA    1 
ATOM   3522 C C     . THR B 2 274 ? 108.523 149.649 107.761 1.00 10.67  ? 263 THR B C     1 
ATOM   3523 O O     . THR B 2 274 ? 107.405 149.818 108.258 1.00 14.83  ? 263 THR B O     1 
ATOM   3524 C CB    . THR B 2 274 ? 108.931 151.772 106.496 1.00 10.66  ? 263 THR B CB    1 
ATOM   3525 O OG1   . THR B 2 274 ? 109.245 152.317 105.209 1.00 10.32  ? 263 THR B OG1   1 
ATOM   3526 C CG2   . THR B 2 274 ? 109.998 152.196 107.491 1.00 13.38  ? 263 THR B CG2   1 
ATOM   3527 N N     . TYR B 2 275 ? 109.488 148.954 108.351 1.00 4.74   ? 264 TYR B N     1 
ATOM   3528 C CA    . TYR B 2 275 ? 109.337 148.320 109.655 1.00 6.91   ? 264 TYR B CA    1 
ATOM   3529 C C     . TYR B 2 275 ? 110.097 149.158 110.675 1.00 10.46  ? 264 TYR B C     1 
ATOM   3530 O O     . TYR B 2 275 ? 111.333 149.181 110.672 1.00 12.18  ? 264 TYR B O     1 
ATOM   3531 C CB    . TYR B 2 275 ? 109.854 146.884 109.622 1.00 9.63   ? 264 TYR B CB    1 
ATOM   3532 C CG    . TYR B 2 275 ? 109.491 146.136 108.359 1.00 10.66  ? 264 TYR B CG    1 
ATOM   3533 C CD1   . TYR B 2 275 ? 108.270 145.487 108.242 1.00 10.78  ? 264 TYR B CD1   1 
ATOM   3534 C CD2   . TYR B 2 275 ? 110.367 146.083 107.284 1.00 8.47   ? 264 TYR B CD2   1 
ATOM   3535 C CE1   . TYR B 2 275 ? 107.932 144.806 107.091 1.00 8.49   ? 264 TYR B CE1   1 
ATOM   3536 C CE2   . TYR B 2 275 ? 110.037 145.404 106.128 1.00 6.61   ? 264 TYR B CE2   1 
ATOM   3537 C CZ    . TYR B 2 275 ? 108.818 144.768 106.038 1.00 9.66   ? 264 TYR B CZ    1 
ATOM   3538 O OH    . TYR B 2 275 ? 108.484 144.089 104.890 1.00 13.93  ? 264 TYR B OH    1 
ATOM   3539 N N     . SER B 2 276 ? 109.359 149.846 111.541 1.00 15.42  ? 265 SER B N     1 
ATOM   3540 C CA    . SER B 2 276 ? 109.966 150.733 112.522 1.00 12.89  ? 265 SER B CA    1 
ATOM   3541 C C     . SER B 2 276 ? 109.002 150.924 113.681 1.00 15.81  ? 265 SER B C     1 
ATOM   3542 O O     . SER B 2 276 ? 107.807 150.638 113.575 1.00 19.64  ? 265 SER B O     1 
ATOM   3543 C CB    . SER B 2 276 ? 110.334 152.084 111.902 1.00 13.11  ? 265 SER B CB    1 
ATOM   3544 O OG    . SER B 2 276 ? 109.180 152.763 111.441 1.00 14.99  ? 265 SER B OG    1 
ATOM   3545 N N     . HIS B 2 277 ? 109.544 151.414 114.793 1.00 23.81  ? 266 HIS B N     1 
ATOM   3546 C CA    . HIS B 2 277 ? 108.744 151.720 115.968 1.00 25.52  ? 266 HIS B CA    1 
ATOM   3547 C C     . HIS B 2 277 ? 109.347 152.928 116.666 1.00 27.19  ? 266 HIS B C     1 
ATOM   3548 O O     . HIS B 2 277 ? 110.555 153.170 116.586 1.00 27.57  ? 266 HIS B O     1 
ATOM   3549 C CB    . HIS B 2 277 ? 108.667 150.528 116.929 1.00 24.51  ? 266 HIS B CB    1 
ATOM   3550 C CG    . HIS B 2 277 ? 107.503 150.585 117.869 1.00 28.09  ? 266 HIS B CG    1 
ATOM   3551 N ND1   . HIS B 2 277 ? 107.512 151.341 119.021 1.00 29.06  ? 266 HIS B ND1   1 
ATOM   3552 C CD2   . HIS B 2 277 ? 106.292 149.980 117.826 1.00 27.07  ? 266 HIS B CD2   1 
ATOM   3553 C CE1   . HIS B 2 277 ? 106.358 151.200 119.647 1.00 26.95  ? 266 HIS B CE1   1 
ATOM   3554 N NE2   . HIS B 2 277 ? 105.600 150.379 118.944 1.00 27.95  ? 266 HIS B NE2   1 
ATOM   3555 N N     . ASP B 2 278 ? 108.491 153.688 117.352 1.00 26.42  ? 267 ASP B N     1 
ATOM   3556 C CA    . ASP B 2 278 ? 108.964 154.868 118.067 1.00 26.98  ? 267 ASP B CA    1 
ATOM   3557 C C     . ASP B 2 278 ? 109.869 154.494 119.234 1.00 26.94  ? 267 ASP B C     1 
ATOM   3558 O O     . ASP B 2 278 ? 110.787 155.251 119.571 1.00 25.63  ? 267 ASP B O     1 
ATOM   3559 C CB    . ASP B 2 278 ? 107.777 155.697 118.556 1.00 26.13  ? 267 ASP B CB    1 
ATOM   3560 C CG    . ASP B 2 278 ? 106.835 156.081 117.432 1.00 29.01  ? 267 ASP B CG    1 
ATOM   3561 O OD1   . ASP B 2 278 ? 107.059 157.136 116.802 1.00 28.12  ? 267 ASP B OD1   1 
ATOM   3562 O OD2   . ASP B 2 278 ? 105.871 155.329 117.179 1.00 30.59  ? 267 ASP B OD2   1 
ATOM   3563 N N     . ASN B 2 279 ? 109.630 153.339 119.859 1.00 24.73  ? 268 ASN B N     1 
ATOM   3564 C CA    . ASN B 2 279 ? 110.482 152.894 120.955 1.00 25.49  ? 268 ASN B CA    1 
ATOM   3565 C C     . ASN B 2 279 ? 111.867 152.479 120.478 1.00 26.40  ? 268 ASN B C     1 
ATOM   3566 O O     . ASN B 2 279 ? 112.798 152.429 121.289 1.00 25.68  ? 268 ASN B O     1 
ATOM   3567 C CB    . ASN B 2 279 ? 109.819 151.733 121.698 1.00 24.13  ? 268 ASN B CB    1 
ATOM   3568 N N     . ILE B 2 280 ? 112.024 152.185 119.192 1.00 22.89  ? 269 ILE B N     1 
ATOM   3569 C CA    . ILE B 2 280 ? 113.315 151.807 118.629 1.00 21.20  ? 269 ILE B CA    1 
ATOM   3570 C C     . ILE B 2 280 ? 113.985 153.062 118.085 1.00 20.91  ? 269 ILE B C     1 
ATOM   3571 O O     . ILE B 2 280 ? 113.398 153.789 117.277 1.00 21.26  ? 269 ILE B O     1 
ATOM   3572 C CB    . ILE B 2 280 ? 113.156 150.747 117.529 1.00 20.80  ? 269 ILE B CB    1 
ATOM   3573 C CG1   . ILE B 2 280 ? 112.500 149.485 118.091 1.00 21.36  ? 269 ILE B CG1   1 
ATOM   3574 C CG2   . ILE B 2 280 ? 114.505 150.409 116.919 1.00 20.65  ? 269 ILE B CG2   1 
ATOM   3575 C CD1   . ILE B 2 280 ? 112.160 148.457 117.037 1.00 19.73  ? 269 ILE B CD1   1 
ATOM   3576 N N     . ILE B 2 281 ? 115.208 153.323 118.539 1.00 20.51  ? 270 ILE B N     1 
ATOM   3577 C CA    . ILE B 2 281 ? 115.978 154.472 118.076 1.00 22.05  ? 270 ILE B CA    1 
ATOM   3578 C C     . ILE B 2 281 ? 117.397 154.109 117.671 1.00 21.65  ? 270 ILE B C     1 
ATOM   3579 O O     . ILE B 2 281 ? 118.085 154.947 117.069 1.00 17.70  ? 270 ILE B O     1 
ATOM   3580 C CB    . ILE B 2 281 ? 116.006 155.596 119.135 1.00 18.00  ? 270 ILE B CB    1 
ATOM   3581 N N     . CYS B 2 282 ? 117.860 152.901 117.974 1.00 14.49  ? 271 CYS B N     1 
ATOM   3582 C CA    . CYS B 2 282 ? 119.212 152.481 117.650 1.00 14.15  ? 271 CYS B CA    1 
ATOM   3583 C C     . CYS B 2 282 ? 119.290 151.968 116.214 1.00 15.76  ? 271 CYS B C     1 
ATOM   3584 O O     . CYS B 2 282 ? 118.284 151.834 115.514 1.00 16.67  ? 271 CYS B O     1 
ATOM   3585 C CB    . CYS B 2 282 ? 119.683 151.407 118.629 1.00 14.19  ? 271 CYS B CB    1 
ATOM   3586 S SG    . CYS B 2 282 ? 118.997 149.769 118.312 1.00 20.95  ? 271 CYS B SG    1 
ATOM   3587 N N     . GLY B 2 283 ? 120.514 151.678 115.777 1.00 13.17  ? 272 GLY B N     1 
ATOM   3588 C CA    . GLY B 2 283 ? 120.750 151.210 114.431 1.00 7.55   ? 272 GLY B CA    1 
ATOM   3589 C C     . GLY B 2 283 ? 120.459 149.732 114.260 1.00 8.29   ? 272 GLY B C     1 
ATOM   3590 O O     . GLY B 2 283 ? 120.155 149.003 115.203 1.00 4.42   ? 272 GLY B O     1 
ATOM   3591 N N     . ILE B 2 284 ? 120.559 149.288 113.010 1.00 11.01  ? 273 ILE B N     1 
ATOM   3592 C CA    . ILE B 2 284 ? 120.280 147.911 112.626 1.00 5.10   ? 273 ILE B CA    1 
ATOM   3593 C C     . ILE B 2 284 ? 121.539 147.326 112.004 1.00 5.38   ? 273 ILE B C     1 
ATOM   3594 O O     . ILE B 2 284 ? 122.103 147.906 111.069 1.00 8.42   ? 273 ILE B O     1 
ATOM   3595 C CB    . ILE B 2 284 ? 119.092 147.829 111.651 1.00 6.68   ? 273 ILE B CB    1 
ATOM   3596 C CG1   . ILE B 2 284 ? 117.948 148.711 112.154 1.00 7.29   ? 273 ILE B CG1   1 
ATOM   3597 C CG2   . ILE B 2 284 ? 118.638 146.390 111.483 1.00 2.72   ? 273 ILE B CG2   1 
ATOM   3598 C CD1   . ILE B 2 284 ? 116.672 148.567 111.377 1.00 9.02   ? 273 ILE B CD1   1 
ATOM   3599 N N     . THR B 2 285 ? 121.976 146.181 112.523 1.00 4.56   ? 274 THR B N     1 
ATOM   3600 C CA    . THR B 2 285 ? 123.212 145.540 112.092 1.00 2.28   ? 274 THR B CA    1 
ATOM   3601 C C     . THR B 2 285 ? 122.987 144.386 111.128 1.00 3.98   ? 274 THR B C     1 
ATOM   3602 O O     . THR B 2 285 ? 123.736 144.241 110.158 1.00 5.88   ? 274 THR B O     1 
ATOM   3603 C CB    . THR B 2 285 ? 123.994 145.027 113.306 1.00 5.39   ? 274 THR B CB    1 
ATOM   3604 O OG1   . THR B 2 285 ? 123.200 144.068 114.015 1.00 1.83   ? 274 THR B OG1   1 
ATOM   3605 C CG2   . THR B 2 285 ? 124.346 146.171 114.235 1.00 7.57   ? 274 THR B CG2   1 
ATOM   3606 N N     . SER B 2 286 ? 121.973 143.561 111.372 1.00 3.98   ? 275 SER B N     1 
ATOM   3607 C CA    . SER B 2 286 ? 121.730 142.375 110.569 1.00 0.00   ? 275 SER B CA    1 
ATOM   3608 C C     . SER B 2 286 ? 120.245 142.271 110.259 1.00 0.38   ? 275 SER B C     1 
ATOM   3609 O O     . SER B 2 286 ? 119.400 142.800 110.984 1.00 3.11   ? 275 SER B O     1 
ATOM   3610 C CB    . SER B 2 286 ? 122.220 141.111 111.284 1.00 2.18   ? 275 SER B CB    1 
ATOM   3611 O OG    . SER B 2 286 ? 121.746 141.073 112.618 1.00 11.44  ? 275 SER B OG    1 
ATOM   3612 N N     . VAL B 2 287 ? 119.935 141.584 109.160 1.00 8.03   ? 276 VAL B N     1 
ATOM   3613 C CA    . VAL B 2 287 ? 118.555 141.377 108.740 1.00 3.91   ? 276 VAL B CA    1 
ATOM   3614 C C     . VAL B 2 287 ? 118.490 140.082 107.943 1.00 3.18   ? 276 VAL B C     1 
ATOM   3615 O O     . VAL B 2 287 ? 119.428 139.724 107.226 1.00 4.52   ? 276 VAL B O     1 
ATOM   3616 C CB    . VAL B 2 287 ? 118.020 142.581 107.923 1.00 0.00   ? 276 VAL B CB    1 
ATOM   3617 C CG1   . VAL B 2 287 ? 118.666 142.646 106.547 1.00 2.00   ? 276 VAL B CG1   1 
ATOM   3618 C CG2   . VAL B 2 287 ? 116.510 142.532 107.815 1.00 6.19   ? 276 VAL B CG2   1 
ATOM   3619 N N     . SER B 2 288 ? 117.380 139.361 108.093 1.00 4.15   ? 277 SER B N     1 
ATOM   3620 C CA    . SER B 2 288 ? 117.179 138.118 107.361 1.00 1.25   ? 277 SER B CA    1 
ATOM   3621 C C     . SER B 2 288 ? 115.696 137.784 107.340 1.00 2.54   ? 277 SER B C     1 
ATOM   3622 O O     . SER B 2 288 ? 114.911 138.297 108.140 1.00 5.54   ? 277 SER B O     1 
ATOM   3623 C CB    . SER B 2 288 ? 117.978 136.964 107.974 1.00 3.88   ? 277 SER B CB    1 
ATOM   3624 O OG    . SER B 2 288 ? 118.104 135.887 107.063 1.00 5.87   ? 277 SER B OG    1 
ATOM   3625 N N     . PHE B 2 289 ? 115.328 136.907 106.412 1.00 4.02   ? 278 PHE B N     1 
ATOM   3626 C CA    . PHE B 2 289 ? 113.962 136.437 106.249 1.00 3.55   ? 278 PHE B CA    1 
ATOM   3627 C C     . PHE B 2 289 ? 113.840 135.001 106.739 1.00 5.31   ? 278 PHE B C     1 
ATOM   3628 O O     . PHE B 2 289 ? 114.827 134.268 106.843 1.00 8.23   ? 278 PHE B O     1 
ATOM   3629 C CB    . PHE B 2 289 ? 113.524 136.512 104.781 1.00 4.58   ? 278 PHE B CB    1 
ATOM   3630 C CG    . PHE B 2 289 ? 113.075 137.874 104.344 1.00 4.91   ? 278 PHE B CG    1 
ATOM   3631 C CD1   . PHE B 2 289 ? 111.813 138.341 104.671 1.00 5.21   ? 278 PHE B CD1   1 
ATOM   3632 C CD2   . PHE B 2 289 ? 113.908 138.682 103.590 1.00 2.17   ? 278 PHE B CD2   1 
ATOM   3633 C CE1   . PHE B 2 289 ? 111.396 139.591 104.262 1.00 3.78   ? 278 PHE B CE1   1 
ATOM   3634 C CE2   . PHE B 2 289 ? 113.496 139.931 103.178 1.00 0.58   ? 278 PHE B CE2   1 
ATOM   3635 C CZ    . PHE B 2 289 ? 112.239 140.387 103.515 1.00 2.96   ? 278 PHE B CZ    1 
ATOM   3636 N N     . SER B 2 290 ? 112.606 134.603 107.037 1.00 2.96   ? 279 SER B N     1 
ATOM   3637 C CA    . SER B 2 290 ? 112.322 133.208 107.330 1.00 3.30   ? 279 SER B CA    1 
ATOM   3638 C C     . SER B 2 290 ? 112.276 132.411 106.026 1.00 7.48   ? 279 SER B C     1 
ATOM   3639 O O     . SER B 2 290 ? 112.508 132.938 104.934 1.00 8.75   ? 279 SER B O     1 
ATOM   3640 C CB    . SER B 2 290 ? 111.015 133.084 108.108 1.00 5.96   ? 279 SER B CB    1 
ATOM   3641 O OG    . SER B 2 290 ? 109.898 133.331 107.274 1.00 11.05  ? 279 SER B OG    1 
ATOM   3642 N N     . LYS B 2 291 ? 111.980 131.114 106.141 1.00 7.01   ? 280 LYS B N     1 
ATOM   3643 C CA    . LYS B 2 291 ? 111.927 130.273 104.949 1.00 6.17   ? 280 LYS B CA    1 
ATOM   3644 C C     . LYS B 2 291 ? 110.825 130.725 104.000 1.00 7.32   ? 280 LYS B C     1 
ATOM   3645 O O     . LYS B 2 291 ? 111.025 130.771 102.781 1.00 10.74  ? 280 LYS B O     1 
ATOM   3646 C CB    . LYS B 2 291 ? 111.733 128.808 105.340 1.00 6.08   ? 280 LYS B CB    1 
ATOM   3647 C CG    . LYS B 2 291 ? 112.046 127.840 104.212 1.00 5.89   ? 280 LYS B CG    1 
ATOM   3648 C CD    . LYS B 2 291 ? 111.835 126.400 104.632 1.00 8.36   ? 280 LYS B CD    1 
ATOM   3649 C CE    . LYS B 2 291 ? 112.122 125.451 103.481 1.00 6.61   ? 280 LYS B CE    1 
ATOM   3650 N NZ    . LYS B 2 291 ? 113.554 125.486 103.079 1.00 6.24   ? 280 LYS B NZ    1 
ATOM   3651 N N     . SER B 2 292 ? 109.652 131.058 104.538 1.00 5.64   ? 281 SER B N     1 
ATOM   3652 C CA    . SER B 2 292 ? 108.564 131.579 103.722 1.00 6.51   ? 281 SER B CA    1 
ATOM   3653 C C     . SER B 2 292 ? 108.680 133.074 103.464 1.00 9.83   ? 281 SER B C     1 
ATOM   3654 O O     . SER B 2 292 ? 107.979 133.590 102.588 1.00 7.71   ? 281 SER B O     1 
ATOM   3655 C CB    . SER B 2 292 ? 107.218 131.282 104.385 1.00 6.77   ? 281 SER B CB    1 
ATOM   3656 O OG    . SER B 2 292 ? 107.119 131.918 105.647 1.00 10.12  ? 281 SER B OG    1 
ATOM   3657 N N     . GLY B 2 293 ? 109.542 133.774 104.197 1.00 11.87  ? 282 GLY B N     1 
ATOM   3658 C CA    . GLY B 2 293 ? 109.667 135.208 104.071 1.00 8.25   ? 282 GLY B CA    1 
ATOM   3659 C C     . GLY B 2 293 ? 108.632 136.009 104.826 1.00 9.45   ? 282 GLY B C     1 
ATOM   3660 O O     . GLY B 2 293 ? 108.676 137.245 104.779 1.00 16.95  ? 282 GLY B O     1 
ATOM   3661 N N     . ARG B 2 294 ? 107.702 135.351 105.521 1.00 9.97   ? 283 ARG B N     1 
ATOM   3662 C CA    . ARG B 2 294 ? 106.678 136.076 106.266 1.00 8.88   ? 283 ARG B CA    1 
ATOM   3663 C C     . ARG B 2 294 ? 107.270 136.830 107.449 1.00 12.97  ? 283 ARG B C     1 
ATOM   3664 O O     . ARG B 2 294 ? 106.799 137.922 107.785 1.00 16.17  ? 283 ARG B O     1 
ATOM   3665 C CB    . ARG B 2 294 ? 105.593 135.109 106.737 1.00 9.49   ? 283 ARG B CB    1 
ATOM   3666 C CG    . ARG B 2 294 ? 104.446 135.769 107.481 1.00 11.26  ? 283 ARG B CG    1 
ATOM   3667 C CD    . ARG B 2 294 ? 103.561 136.565 106.541 1.00 11.68  ? 283 ARG B CD    1 
ATOM   3668 N NE    . ARG B 2 294 ? 102.683 137.476 107.265 1.00 13.42  ? 283 ARG B NE    1 
ATOM   3669 C CZ    . ARG B 2 294 ? 101.416 137.220 107.558 1.00 17.08  ? 283 ARG B CZ    1 
ATOM   3670 N NH1   . ARG B 2 294 ? 100.841 136.082 107.207 1.00 14.49  ? 283 ARG B NH1   1 
ATOM   3671 N NH2   . ARG B 2 294 ? 100.709 138.128 108.225 1.00 17.38  ? 283 ARG B NH2   1 
ATOM   3672 N N     . LEU B 2 295 ? 108.292 136.272 108.089 1.00 12.08  ? 284 LEU B N     1 
ATOM   3673 C CA    . LEU B 2 295 ? 108.931 136.893 109.239 1.00 9.06   ? 284 LEU B CA    1 
ATOM   3674 C C     . LEU B 2 295 ? 110.255 137.514 108.819 1.00 5.58   ? 284 LEU B C     1 
ATOM   3675 O O     . LEU B 2 295 ? 111.060 136.870 108.139 1.00 8.25   ? 284 LEU B O     1 
ATOM   3676 C CB    . LEU B 2 295 ? 109.161 135.872 110.354 1.00 8.18   ? 284 LEU B CB    1 
ATOM   3677 C CG    . LEU B 2 295 ? 107.917 135.177 110.903 1.00 7.68   ? 284 LEU B CG    1 
ATOM   3678 C CD1   . LEU B 2 295 ? 108.307 134.116 111.917 1.00 9.06   ? 284 LEU B CD1   1 
ATOM   3679 C CD2   . LEU B 2 295 ? 106.966 136.191 111.516 1.00 9.81   ? 284 LEU B CD2   1 
ATOM   3680 N N     . LEU B 2 296 ? 110.471 138.762 109.219 1.00 7.71   ? 285 LEU B N     1 
ATOM   3681 C CA    . LEU B 2 296 ? 111.719 139.470 108.968 1.00 10.74  ? 285 LEU B CA    1 
ATOM   3682 C C     . LEU B 2 296 ? 112.438 139.662 110.295 1.00 6.13   ? 285 LEU B C     1 
ATOM   3683 O O     . LEU B 2 296 ? 111.940 140.368 111.176 1.00 6.11   ? 285 LEU B O     1 
ATOM   3684 C CB    . LEU B 2 296 ? 111.458 140.817 108.295 1.00 9.05   ? 285 LEU B CB    1 
ATOM   3685 C CG    . LEU B 2 296 ? 112.704 141.628 107.945 1.00 2.74   ? 285 LEU B CG    1 
ATOM   3686 C CD1   . LEU B 2 296 ? 113.476 140.936 106.839 1.00 3.00   ? 285 LEU B CD1   1 
ATOM   3687 C CD2   . LEU B 2 296 ? 112.332 143.042 107.543 1.00 4.80   ? 285 LEU B CD2   1 
ATOM   3688 N N     . LEU B 2 297 ? 113.601 139.036 110.438 1.00 3.87   ? 286 LEU B N     1 
ATOM   3689 C CA    . LEU B 2 297 ? 114.375 139.100 111.671 1.00 5.93   ? 286 LEU B CA    1 
ATOM   3690 C C     . LEU B 2 297 ? 115.494 140.117 111.497 1.00 7.50   ? 286 LEU B C     1 
ATOM   3691 O O     . LEU B 2 297 ? 116.294 140.009 110.562 1.00 9.80   ? 286 LEU B O     1 
ATOM   3692 C CB    . LEU B 2 297 ? 114.941 137.727 112.030 1.00 6.14   ? 286 LEU B CB    1 
ATOM   3693 C CG    . LEU B 2 297 ? 113.910 136.635 112.321 1.00 7.71   ? 286 LEU B CG    1 
ATOM   3694 C CD1   . LEU B 2 297 ? 113.767 135.699 111.132 1.00 4.97   ? 286 LEU B CD1   1 
ATOM   3695 C CD2   . LEU B 2 297 ? 114.288 135.865 113.573 1.00 9.20   ? 286 LEU B CD2   1 
ATOM   3696 N N     . ALA B 2 298 ? 115.549 141.100 112.393 1.00 7.14   ? 287 ALA B N     1 
ATOM   3697 C CA    . ALA B 2 298 ? 116.535 142.167 112.316 1.00 4.81   ? 287 ALA B CA    1 
ATOM   3698 C C     . ALA B 2 298 ? 117.245 142.307 113.653 1.00 5.25   ? 287 ALA B C     1 
ATOM   3699 O O     . ALA B 2 298 ? 116.596 142.360 114.702 1.00 7.46   ? 287 ALA B O     1 
ATOM   3700 C CB    . ALA B 2 298 ? 115.882 143.496 111.922 1.00 3.75   ? 287 ALA B CB    1 
ATOM   3701 N N     . GLY B 2 299 ? 118.573 142.373 113.613 1.00 5.24   ? 288 GLY B N     1 
ATOM   3702 C CA    . GLY B 2 299 ? 119.360 142.611 114.809 1.00 3.17   ? 288 GLY B CA    1 
ATOM   3703 C C     . GLY B 2 299 ? 119.631 144.096 114.993 1.00 2.93   ? 288 GLY B C     1 
ATOM   3704 O O     . GLY B 2 299 ? 119.929 144.810 114.040 1.00 6.60   ? 288 GLY B O     1 
ATOM   3705 N N     . TYR B 2 300 ? 119.537 144.547 116.241 1.00 7.25   ? 289 TYR B N     1 
ATOM   3706 C CA    . TYR B 2 300 ? 119.620 145.962 116.564 1.00 9.05   ? 289 TYR B CA    1 
ATOM   3707 C C     . TYR B 2 300 ? 120.757 146.212 117.544 1.00 10.15  ? 289 TYR B C     1 
ATOM   3708 O O     . TYR B 2 300 ? 121.292 145.287 118.161 1.00 10.75  ? 289 TYR B O     1 
ATOM   3709 C CB    . TYR B 2 300 ? 118.302 146.478 117.155 1.00 7.58   ? 289 TYR B CB    1 
ATOM   3710 C CG    . TYR B 2 300 ? 117.155 146.537 116.173 1.00 9.02   ? 289 TYR B CG    1 
ATOM   3711 C CD1   . TYR B 2 300 ? 116.481 145.386 115.790 1.00 6.21   ? 289 TYR B CD1   1 
ATOM   3712 C CD2   . TYR B 2 300 ? 116.737 147.748 115.639 1.00 9.31   ? 289 TYR B CD2   1 
ATOM   3713 C CE1   . TYR B 2 300 ? 115.432 145.437 114.895 1.00 7.40   ? 289 TYR B CE1   1 
ATOM   3714 C CE2   . TYR B 2 300 ? 115.687 147.809 114.745 1.00 10.18  ? 289 TYR B CE2   1 
ATOM   3715 C CZ    . TYR B 2 300 ? 115.038 146.650 114.377 1.00 12.82  ? 289 TYR B CZ    1 
ATOM   3716 O OH    . TYR B 2 300 ? 113.991 146.707 113.486 1.00 17.68  ? 289 TYR B OH    1 
ATOM   3717 N N     . ASP B 2 301 ? 121.125 147.489 117.677 1.00 10.90  ? 290 ASP B N     1 
ATOM   3718 C CA    . ASP B 2 301 ? 122.159 147.880 118.629 1.00 10.63  ? 290 ASP B CA    1 
ATOM   3719 C C     . ASP B 2 301 ? 121.671 147.831 120.070 1.00 13.95  ? 290 ASP B C     1 
ATOM   3720 O O     . ASP B 2 301 ? 122.495 147.863 120.990 1.00 12.62  ? 290 ASP B O     1 
ATOM   3721 C CB    . ASP B 2 301 ? 122.667 149.289 118.318 1.00 8.93   ? 290 ASP B CB    1 
ATOM   3722 C CG    . ASP B 2 301 ? 123.129 149.439 116.887 1.00 11.69  ? 290 ASP B CG    1 
ATOM   3723 O OD1   . ASP B 2 301 ? 123.346 148.408 116.222 1.00 12.59  ? 290 ASP B OD1   1 
ATOM   3724 O OD2   . ASP B 2 301 ? 123.280 150.590 116.428 1.00 11.17  ? 290 ASP B OD2   1 
ATOM   3725 N N     . ASP B 2 302 ? 120.358 147.749 120.289 1.00 11.02  ? 291 ASP B N     1 
ATOM   3726 C CA    . ASP B 2 302 ? 119.787 147.743 121.629 1.00 10.34  ? 291 ASP B CA    1 
ATOM   3727 C C     . ASP B 2 302 ? 119.874 146.380 122.304 1.00 11.91  ? 291 ASP B C     1 
ATOM   3728 O O     . ASP B 2 302 ? 119.141 146.132 123.270 1.00 15.41  ? 291 ASP B O     1 
ATOM   3729 C CB    . ASP B 2 302 ? 118.333 148.225 121.587 1.00 11.99  ? 291 ASP B CB    1 
ATOM   3730 C CG    . ASP B 2 302 ? 117.386 147.198 120.989 1.00 15.48  ? 291 ASP B CG    1 
ATOM   3731 O OD1   . ASP B 2 302 ? 117.847 146.306 120.249 1.00 16.87  ? 291 ASP B OD1   1 
ATOM   3732 O OD2   . ASP B 2 302 ? 116.171 147.285 121.262 1.00 14.62  ? 291 ASP B OD2   1 
ATOM   3733 N N     . PHE B 2 303 ? 120.736 145.500 121.797 1.00 7.75   ? 292 PHE B N     1 
ATOM   3734 C CA    . PHE B 2 303 ? 121.065 144.171 122.310 1.00 9.44   ? 292 PHE B CA    1 
ATOM   3735 C C     . PHE B 2 303 ? 119.966 143.164 121.989 1.00 11.54  ? 292 PHE B C     1 
ATOM   3736 O O     . PHE B 2 303 ? 120.093 141.996 122.374 1.00 14.56  ? 292 PHE B O     1 
ATOM   3737 C CB    . PHE B 2 303 ? 121.328 144.139 123.827 1.00 10.82  ? 292 PHE B CB    1 
ATOM   3738 C CG    . PHE B 2 303 ? 122.385 145.111 124.301 1.00 11.01  ? 292 PHE B CG    1 
ATOM   3739 C CD1   . PHE B 2 303 ? 123.164 145.829 123.407 1.00 10.25  ? 292 PHE B CD1   1 
ATOM   3740 C CD2   . PHE B 2 303 ? 122.599 145.295 125.656 1.00 12.55  ? 292 PHE B CD2   1 
ATOM   3741 C CE1   . PHE B 2 303 ? 124.126 146.711 123.854 1.00 8.41   ? 292 PHE B CE1   1 
ATOM   3742 C CE2   . PHE B 2 303 ? 123.561 146.176 126.108 1.00 12.74  ? 292 PHE B CE2   1 
ATOM   3743 C CZ    . PHE B 2 303 ? 124.325 146.884 125.206 1.00 10.59  ? 292 PHE B CZ    1 
ATOM   3744 N N     . ASN B 2 304 ? 118.903 143.564 121.299 1.00 11.74  ? 293 ASN B N     1 
ATOM   3745 C CA    . ASN B 2 304 ? 117.770 142.696 121.028 1.00 11.31  ? 293 ASN B CA    1 
ATOM   3746 C C     . ASN B 2 304 ? 117.599 142.486 119.530 1.00 13.29  ? 293 ASN B C     1 
ATOM   3747 O O     . ASN B 2 304 ? 118.117 143.242 118.705 1.00 14.01  ? 293 ASN B O     1 
ATOM   3748 C CB    . ASN B 2 304 ? 116.479 143.278 121.617 1.00 8.83   ? 293 ASN B CB    1 
ATOM   3749 C CG    . ASN B 2 304 ? 116.536 143.418 123.123 1.00 15.75  ? 293 ASN B CG    1 
ATOM   3750 O OD1   . ASN B 2 304 ? 116.841 142.463 123.836 1.00 19.49  ? 293 ASN B OD1   1 
ATOM   3751 N ND2   . ASN B 2 304 ? 116.239 144.613 123.618 1.00 15.97  ? 293 ASN B ND2   1 
ATOM   3752 N N     . CYS B 2 305 ? 116.860 141.435 119.191 1.00 10.28  ? 294 CYS B N     1 
ATOM   3753 C CA    . CYS B 2 305 ? 116.441 141.163 117.825 1.00 7.07   ? 294 CYS B CA    1 
ATOM   3754 C C     . CYS B 2 305 ? 114.933 141.337 117.724 1.00 7.80   ? 294 CYS B C     1 
ATOM   3755 O O     . CYS B 2 305 ? 114.203 141.019 118.664 1.00 12.52  ? 294 CYS B O     1 
ATOM   3756 C CB    . CYS B 2 305 ? 116.835 139.749 117.396 1.00 7.41   ? 294 CYS B CB    1 
ATOM   3757 S SG    . CYS B 2 305 ? 116.097 139.216 115.838 1.00 17.71  ? 294 CYS B SG    1 
ATOM   3758 N N     . ASN B 2 306 ? 114.466 141.847 116.591 1.00 9.72   ? 295 ASN B N     1 
ATOM   3759 C CA    . ASN B 2 306 ? 113.044 142.064 116.369 1.00 7.82   ? 295 ASN B CA    1 
ATOM   3760 C C     . ASN B 2 306 ? 112.581 141.234 115.183 1.00 7.94   ? 295 ASN B C     1 
ATOM   3761 O O     . ASN B 2 306 ? 113.205 141.261 114.117 1.00 11.55  ? 295 ASN B O     1 
ATOM   3762 C CB    . ASN B 2 306 ? 112.740 143.546 116.136 1.00 9.28   ? 295 ASN B CB    1 
ATOM   3763 C CG    . ASN B 2 306 ? 112.721 144.345 117.424 1.00 13.70  ? 295 ASN B CG    1 
ATOM   3764 O OD1   . ASN B 2 306 ? 111.857 144.147 118.277 1.00 17.28  ? 295 ASN B OD1   1 
ATOM   3765 N ND2   . ASN B 2 306 ? 113.677 145.253 117.572 1.00 13.52  ? 295 ASN B ND2   1 
ATOM   3766 N N     . VAL B 2 307 ? 111.493 140.493 115.374 1.00 8.89   ? 296 VAL B N     1 
ATOM   3767 C CA    . VAL B 2 307 ? 110.857 139.725 114.315 1.00 11.03  ? 296 VAL B CA    1 
ATOM   3768 C C     . VAL B 2 307 ? 109.593 140.468 113.914 1.00 12.23  ? 296 VAL B C     1 
ATOM   3769 O O     . VAL B 2 307 ? 108.656 140.588 114.713 1.00 15.18  ? 296 VAL B O     1 
ATOM   3770 C CB    . VAL B 2 307 ? 110.535 138.293 114.772 1.00 7.22   ? 296 VAL B CB    1 
ATOM   3771 C CG1   . VAL B 2 307 ? 110.140 137.431 113.585 1.00 8.38   ? 296 VAL B CG1   1 
ATOM   3772 C CG2   . VAL B 2 307 ? 111.720 137.693 115.511 1.00 8.85   ? 296 VAL B CG2   1 
ATOM   3773 N N     . TRP B 2 308 ? 109.575 140.968 112.683 1.00 9.58   ? 297 TRP B N     1 
ATOM   3774 C CA    . TRP B 2 308 ? 108.473 141.739 112.134 1.00 10.12  ? 297 TRP B CA    1 
ATOM   3775 C C     . TRP B 2 308 ? 107.655 140.875 111.186 1.00 11.56  ? 297 TRP B C     1 
ATOM   3776 O O     . TRP B 2 308 ? 108.179 139.963 110.540 1.00 14.69  ? 297 TRP B O     1 
ATOM   3777 C CB    . TRP B 2 308 ? 108.981 142.966 111.369 1.00 12.59  ? 297 TRP B CB    1 
ATOM   3778 C CG    . TRP B 2 308 ? 109.882 143.868 112.149 1.00 10.99  ? 297 TRP B CG    1 
ATOM   3779 C CD1   . TRP B 2 308 ? 111.218 143.704 112.366 1.00 6.41   ? 297 TRP B CD1   1 
ATOM   3780 C CD2   . TRP B 2 308 ? 109.518 145.092 112.796 1.00 10.56  ? 297 TRP B CD2   1 
ATOM   3781 N NE1   . TRP B 2 308 ? 111.706 144.743 113.119 1.00 7.27   ? 297 TRP B NE1   1 
ATOM   3782 C CE2   . TRP B 2 308 ? 110.682 145.609 113.396 1.00 11.00  ? 297 TRP B CE2   1 
ATOM   3783 C CE3   . TRP B 2 308 ? 108.319 145.797 112.932 1.00 9.81   ? 297 TRP B CE3   1 
ATOM   3784 C CZ2   . TRP B 2 308 ? 110.682 146.799 114.119 1.00 11.03  ? 297 TRP B CZ2   1 
ATOM   3785 C CZ3   . TRP B 2 308 ? 108.321 146.976 113.651 1.00 10.76  ? 297 TRP B CZ3   1 
ATOM   3786 C CH2   . TRP B 2 308 ? 109.495 147.466 114.235 1.00 11.52  ? 297 TRP B CH2   1 
ATOM   3787 N N     . ASP B 2 309 ? 106.363 141.176 111.104 1.00 14.63  ? 298 ASP B N     1 
ATOM   3788 C CA    . ASP B 2 309 ? 105.518 140.605 110.063 1.00 12.50  ? 298 ASP B CA    1 
ATOM   3789 C C     . ASP B 2 309 ? 105.828 141.316 108.752 1.00 15.27  ? 298 ASP B C     1 
ATOM   3790 O O     . ASP B 2 309 ? 105.473 142.485 108.574 1.00 21.65  ? 298 ASP B O     1 
ATOM   3791 C CB    . ASP B 2 309 ? 104.046 140.748 110.437 1.00 14.84  ? 298 ASP B CB    1 
ATOM   3792 C CG    . ASP B 2 309 ? 103.144 139.844 109.621 1.00 18.19  ? 298 ASP B CG    1 
ATOM   3793 O OD1   . ASP B 2 309 ? 103.623 139.253 108.631 1.00 15.83  ? 298 ASP B OD1   1 
ATOM   3794 O OD2   . ASP B 2 309 ? 101.951 139.726 109.969 1.00 20.92  ? 298 ASP B OD2   1 
ATOM   3795 N N     . ALA B 2 310 ? 106.499 140.616 107.833 1.00 14.55  ? 299 ALA B N     1 
ATOM   3796 C CA    . ALA B 2 310 ? 106.960 141.250 106.602 1.00 12.73  ? 299 ALA B CA    1 
ATOM   3797 C C     . ALA B 2 310 ? 105.814 141.750 105.736 1.00 13.03  ? 299 ALA B C     1 
ATOM   3798 O O     . ALA B 2 310 ? 106.036 142.598 104.864 1.00 16.75  ? 299 ALA B O     1 
ATOM   3799 C CB    . ALA B 2 310 ? 107.829 140.278 105.803 1.00 9.30   ? 299 ALA B CB    1 
ATOM   3800 N N     . LEU B 2 311 ? 104.598 141.251 105.951 1.00 14.54  ? 300 LEU B N     1 
ATOM   3801 C CA    . LEU B 2 311 ? 103.445 141.680 105.173 1.00 19.73  ? 300 LEU B CA    1 
ATOM   3802 C C     . LEU B 2 311 ? 102.612 142.751 105.863 1.00 20.87  ? 300 LEU B C     1 
ATOM   3803 O O     . LEU B 2 311 ? 101.894 143.487 105.179 1.00 22.35  ? 300 LEU B O     1 
ATOM   3804 C CB    . LEU B 2 311 ? 102.550 140.477 104.850 1.00 20.41  ? 300 LEU B CB    1 
ATOM   3805 C CG    . LEU B 2 311 ? 103.167 139.401 103.954 1.00 18.02  ? 300 LEU B CG    1 
ATOM   3806 C CD1   . LEU B 2 311 ? 102.138 138.343 103.598 1.00 18.96  ? 300 LEU B CD1   1 
ATOM   3807 C CD2   . LEU B 2 311 ? 103.757 140.021 102.699 1.00 17.46  ? 300 LEU B CD2   1 
ATOM   3808 N N     . LYS B 2 312 ? 102.691 142.862 107.189 1.00 19.02  ? 301 LYS B N     1 
ATOM   3809 C CA    . LYS B 2 312 ? 101.881 143.812 107.936 1.00 18.79  ? 301 LYS B CA    1 
ATOM   3810 C C     . LYS B 2 312 ? 102.699 144.804 108.752 1.00 19.83  ? 301 LYS B C     1 
ATOM   3811 O O     . LYS B 2 312 ? 102.110 145.678 109.399 1.00 23.47  ? 301 LYS B O     1 
ATOM   3812 C CB    . LYS B 2 312 ? 100.914 143.066 108.866 1.00 20.06  ? 301 LYS B CB    1 
ATOM   3813 C CG    . LYS B 2 312 ? 99.979  142.109 108.145 1.00 19.73  ? 301 LYS B CG    1 
ATOM   3814 C CD    . LYS B 2 312 ? 99.017  141.439 109.111 1.00 20.67  ? 301 LYS B CD    1 
ATOM   3815 C CE    . LYS B 2 312 ? 97.908  142.386 109.532 1.00 19.84  ? 301 LYS B CE    1 
ATOM   3816 N NZ    . LYS B 2 312 ? 96.775  142.373 108.568 1.00 24.19  ? 301 LYS B NZ    1 
ATOM   3817 N N     . ALA B 2 313 ? 104.026 144.687 108.754 1.00 15.82  ? 302 ALA B N     1 
ATOM   3818 C CA    . ALA B 2 313 ? 104.948 145.552 109.489 1.00 15.67  ? 302 ALA B CA    1 
ATOM   3819 C C     . ALA B 2 313 ? 104.744 145.499 110.998 1.00 17.72  ? 302 ALA B C     1 
ATOM   3820 O O     . ALA B 2 313 ? 105.359 146.287 111.728 1.00 19.32  ? 302 ALA B O     1 
ATOM   3821 C CB    . ALA B 2 313 ? 104.870 147.007 109.011 1.00 15.40  ? 302 ALA B CB    1 
ATOM   3822 N N     . ASP B 2 314 ? 103.900 144.598 111.490 1.00 16.02  ? 303 ASP B N     1 
ATOM   3823 C CA    . ASP B 2 314 ? 103.726 144.452 112.927 1.00 15.93  ? 303 ASP B CA    1 
ATOM   3824 C C     . ASP B 2 314 ? 104.923 143.728 113.527 1.00 15.85  ? 303 ASP B C     1 
ATOM   3825 O O     . ASP B 2 314 ? 105.444 142.771 112.949 1.00 19.40  ? 303 ASP B O     1 
ATOM   3826 C CB    . ASP B 2 314 ? 102.440 143.685 113.234 1.00 19.02  ? 303 ASP B CB    1 
ATOM   3827 C CG    . ASP B 2 314 ? 101.195 144.447 112.827 1.00 21.75  ? 303 ASP B CG    1 
ATOM   3828 O OD1   . ASP B 2 314 ? 101.329 145.565 112.287 1.00 19.95  ? 303 ASP B OD1   1 
ATOM   3829 O OD2   . ASP B 2 314 ? 100.081 143.927 113.047 1.00 21.24  ? 303 ASP B OD2   1 
ATOM   3830 N N     . ARG B 2 315 ? 105.362 144.192 114.693 1.00 15.28  ? 304 ARG B N     1 
ATOM   3831 C CA    . ARG B 2 315 ? 106.460 143.542 115.403 1.00 14.18  ? 304 ARG B CA    1 
ATOM   3832 C C     . ARG B 2 315 ? 105.940 142.243 115.999 1.00 16.32  ? 304 ARG B C     1 
ATOM   3833 O O     . ARG B 2 315 ? 105.339 142.232 117.075 1.00 19.50  ? 304 ARG B O     1 
ATOM   3834 C CB    . ARG B 2 315 ? 107.026 144.463 116.477 1.00 17.37  ? 304 ARG B CB    1 
ATOM   3835 C CG    . ARG B 2 315 ? 108.416 144.071 116.948 1.00 18.32  ? 304 ARG B CG    1 
ATOM   3836 C CD    . ARG B 2 315 ? 108.673 144.541 118.368 1.00 17.83  ? 304 ARG B CD    1 
ATOM   3837 N NE    . ARG B 2 315 ? 108.730 145.995 118.459 1.00 19.68  ? 304 ARG B NE    1 
ATOM   3838 C CZ    . ARG B 2 315 ? 109.382 146.661 119.402 1.00 21.10  ? 304 ARG B CZ    1 
ATOM   3839 N NH1   . ARG B 2 315 ? 110.050 146.032 120.355 1.00 16.45  ? 304 ARG B NH1   1 
ATOM   3840 N NH2   . ARG B 2 315 ? 109.364 147.990 119.388 1.00 20.80  ? 304 ARG B NH2   1 
ATOM   3841 N N     . ALA B 2 316 ? 106.162 141.137 115.285 1.00 17.66  ? 305 ALA B N     1 
ATOM   3842 C CA    . ALA B 2 316 ? 105.624 139.851 115.714 1.00 13.66  ? 305 ALA B CA    1 
ATOM   3843 C C     . ALA B 2 316 ? 106.217 139.413 117.047 1.00 15.44  ? 305 ALA B C     1 
ATOM   3844 O O     . ALA B 2 316 ? 105.502 138.896 117.912 1.00 20.20  ? 305 ALA B O     1 
ATOM   3845 C CB    . ALA B 2 316 ? 105.878 138.793 114.642 1.00 13.91  ? 305 ALA B CB    1 
ATOM   3846 N N     . GLY B 2 317 ? 107.516 139.611 117.232 1.00 12.19  ? 306 GLY B N     1 
ATOM   3847 C CA    . GLY B 2 317 ? 108.135 139.157 118.465 1.00 12.35  ? 306 GLY B CA    1 
ATOM   3848 C C     . GLY B 2 317 ? 109.496 139.782 118.670 1.00 13.02  ? 306 GLY B C     1 
ATOM   3849 O O     . GLY B 2 317 ? 109.992 140.542 117.836 1.00 15.50  ? 306 GLY B O     1 
ATOM   3850 N N     . VAL B 2 318 ? 110.101 139.439 119.804 1.00 8.88   ? 307 VAL B N     1 
ATOM   3851 C CA    . VAL B 2 318 ? 111.422 139.932 120.170 1.00 8.31   ? 307 VAL B CA    1 
ATOM   3852 C C     . VAL B 2 318 ? 112.273 138.758 120.637 1.00 10.38  ? 307 VAL B C     1 
ATOM   3853 O O     . VAL B 2 318 ? 111.808 137.907 121.404 1.00 13.86  ? 307 VAL B O     1 
ATOM   3854 C CB    . VAL B 2 318 ? 111.346 141.030 121.252 1.00 10.88  ? 307 VAL B CB    1 
ATOM   3855 C CG1   . VAL B 2 318 ? 110.686 140.511 122.523 1.00 12.74  ? 307 VAL B CG1   1 
ATOM   3856 C CG2   . VAL B 2 318 ? 112.730 141.582 121.550 1.00 11.78  ? 307 VAL B CG2   1 
ATOM   3857 N N     . LEU B 2 319 ? 113.505 138.696 120.140 1.00 7.74   ? 308 LEU B N     1 
ATOM   3858 C CA    . LEU B 2 319 ? 114.503 137.726 120.581 1.00 6.00   ? 308 LEU B CA    1 
ATOM   3859 C C     . LEU B 2 319 ? 115.475 138.463 121.492 1.00 9.47   ? 308 LEU B C     1 
ATOM   3860 O O     . LEU B 2 319 ? 116.332 139.219 121.026 1.00 12.80  ? 308 LEU B O     1 
ATOM   3861 C CB    . LEU B 2 319 ? 115.218 137.100 119.389 1.00 5.22   ? 308 LEU B CB    1 
ATOM   3862 C CG    . LEU B 2 319 ? 114.664 135.811 118.778 1.00 9.12   ? 308 LEU B CG    1 
ATOM   3863 C CD1   . LEU B 2 319 ? 113.183 135.929 118.464 1.00 10.14  ? 308 LEU B CD1   1 
ATOM   3864 C CD2   . LEU B 2 319 ? 115.446 135.452 117.527 1.00 8.72   ? 308 LEU B CD2   1 
ATOM   3865 N N     . ALA B 2 320 ? 115.333 138.254 122.796 1.00 13.23  ? 309 ALA B N     1 
ATOM   3866 C CA    . ALA B 2 320 ? 116.164 138.900 123.798 1.00 7.82   ? 309 ALA B CA    1 
ATOM   3867 C C     . ALA B 2 320 ? 116.954 137.854 124.571 1.00 9.53   ? 309 ALA B C     1 
ATOM   3868 O O     . ALA B 2 320 ? 116.494 136.726 124.771 1.00 10.03  ? 309 ALA B O     1 
ATOM   3869 C CB    . ALA B 2 320 ? 115.318 139.735 124.762 1.00 9.38   ? 309 ALA B CB    1 
ATOM   3870 N N     . GLY B 2 321 ? 118.142 138.245 125.022 1.00 10.34  ? 310 GLY B N     1 
ATOM   3871 C CA    . GLY B 2 321 ? 119.022 137.324 125.711 1.00 9.68   ? 310 GLY B CA    1 
ATOM   3872 C C     . GLY B 2 321 ? 120.488 137.543 125.403 1.00 11.05  ? 310 GLY B C     1 
ATOM   3873 O O     . GLY B 2 321 ? 121.352 136.850 125.945 1.00 12.95  ? 310 GLY B O     1 
ATOM   3874 N N     . HIS B 2 322 ? 120.782 138.505 124.535 1.00 9.19   ? 311 HIS B N     1 
ATOM   3875 C CA    . HIS B 2 322 ? 122.153 138.893 124.232 1.00 5.64   ? 311 HIS B CA    1 
ATOM   3876 C C     . HIS B 2 322 ? 122.527 140.099 125.082 1.00 7.88   ? 311 HIS B C     1 
ATOM   3877 O O     . HIS B 2 322 ? 121.785 141.085 125.132 1.00 9.04   ? 311 HIS B O     1 
ATOM   3878 C CB    . HIS B 2 322 ? 122.320 139.213 122.747 1.00 6.17   ? 311 HIS B CB    1 
ATOM   3879 C CG    . HIS B 2 322 ? 122.467 138.001 121.881 1.00 10.83  ? 311 HIS B CG    1 
ATOM   3880 N ND1   . HIS B 2 322 ? 123.551 137.153 121.965 1.00 8.87   ? 311 HIS B ND1   1 
ATOM   3881 C CD2   . HIS B 2 322 ? 121.670 137.496 120.910 1.00 8.01   ? 311 HIS B CD2   1 
ATOM   3882 C CE1   . HIS B 2 322 ? 123.413 136.178 121.085 1.00 3.51   ? 311 HIS B CE1   1 
ATOM   3883 N NE2   . HIS B 2 322 ? 122.280 136.362 120.433 1.00 5.41   ? 311 HIS B NE2   1 
ATOM   3884 N N     . ASP B 2 323 ? 123.676 140.016 125.750 1.00 9.00   ? 312 ASP B N     1 
ATOM   3885 C CA    . ASP B 2 323 ? 124.112 141.063 126.665 1.00 9.90   ? 312 ASP B CA    1 
ATOM   3886 C C     . ASP B 2 323 ? 124.790 142.230 125.960 1.00 11.59  ? 312 ASP B C     1 
ATOM   3887 O O     . ASP B 2 323 ? 125.105 143.228 126.618 1.00 13.53  ? 312 ASP B O     1 
ATOM   3888 C CB    . ASP B 2 323 ? 125.059 140.479 127.717 1.00 7.99   ? 312 ASP B CB    1 
ATOM   3889 N N     . ASN B 2 324 ? 125.022 142.136 124.653 1.00 9.31   ? 313 ASN B N     1 
ATOM   3890 C CA    . ASN B 2 324 ? 125.645 143.210 123.896 1.00 4.60   ? 313 ASN B CA    1 
ATOM   3891 C C     . ASN B 2 324 ? 124.966 143.308 122.536 1.00 7.14   ? 313 ASN B C     1 
ATOM   3892 O O     . ASN B 2 324 ? 123.978 142.620 122.260 1.00 10.84  ? 313 ASN B O     1 
ATOM   3893 C CB    . ASN B 2 324 ? 127.155 142.988 123.758 1.00 8.61   ? 313 ASN B CB    1 
ATOM   3894 C CG    . ASN B 2 324 ? 127.924 144.287 123.616 1.00 8.42   ? 313 ASN B CG    1 
ATOM   3895 O OD1   . ASN B 2 324 ? 127.378 145.300 123.182 1.00 9.21   ? 313 ASN B OD1   1 
ATOM   3896 N ND2   . ASN B 2 324 ? 129.199 144.262 123.983 1.00 9.75   ? 313 ASN B ND2   1 
ATOM   3897 N N     . ARG B 2 325 ? 125.502 144.182 121.686 1.00 5.86   ? 314 ARG B N     1 
ATOM   3898 C CA    . ARG B 2 325 ? 124.903 144.449 120.385 1.00 5.34   ? 314 ARG B CA    1 
ATOM   3899 C C     . ARG B 2 325 ? 124.864 143.189 119.530 1.00 3.40   ? 314 ARG B C     1 
ATOM   3900 O O     . ARG B 2 325 ? 125.868 142.485 119.393 1.00 5.51   ? 314 ARG B O     1 
ATOM   3901 C CB    . ARG B 2 325 ? 125.692 145.546 119.671 1.00 6.62   ? 314 ARG B CB    1 
ATOM   3902 C CG    . ARG B 2 325 ? 125.397 145.669 118.189 1.00 8.11   ? 314 ARG B CG    1 
ATOM   3903 C CD    . ARG B 2 325 ? 126.391 146.593 117.510 1.00 6.56   ? 314 ARG B CD    1 
ATOM   3904 N NE    . ARG B 2 325 ? 126.330 147.950 118.039 1.00 6.05   ? 314 ARG B NE    1 
ATOM   3905 C CZ    . ARG B 2 325 ? 126.749 149.026 117.388 1.00 5.74   ? 314 ARG B CZ    1 
ATOM   3906 N NH1   . ARG B 2 325 ? 127.274 148.941 116.178 1.00 3.98   ? 314 ARG B NH1   1 
ATOM   3907 N NH2   . ARG B 2 325 ? 126.638 150.218 117.967 1.00 6.75   ? 314 ARG B NH2   1 
ATOM   3908 N N     . VAL B 2 326 ? 123.702 142.914 118.944 1.00 5.60   ? 315 VAL B N     1 
ATOM   3909 C CA    . VAL B 2 326 ? 123.543 141.785 118.032 1.00 5.21   ? 315 VAL B CA    1 
ATOM   3910 C C     . VAL B 2 326 ? 124.165 142.180 116.697 1.00 7.92   ? 315 VAL B C     1 
ATOM   3911 O O     . VAL B 2 326 ? 123.654 143.057 115.997 1.00 8.16   ? 315 VAL B O     1 
ATOM   3912 C CB    . VAL B 2 326 ? 122.071 141.392 117.868 1.00 4.77   ? 315 VAL B CB    1 
ATOM   3913 C CG1   . VAL B 2 326 ? 121.903 140.432 116.700 1.00 5.14   ? 315 VAL B CG1   1 
ATOM   3914 C CG2   . VAL B 2 326 ? 121.544 140.769 119.148 1.00 9.28   ? 315 VAL B CG2   1 
ATOM   3915 N N     . SER B 2 327 ? 125.274 141.533 116.343 1.00 5.64   ? 316 SER B N     1 
ATOM   3916 C CA    . SER B 2 327 ? 126.047 141.934 115.175 1.00 4.33   ? 316 SER B CA    1 
ATOM   3917 C C     . SER B 2 327 ? 125.662 141.170 113.915 1.00 5.64   ? 316 SER B C     1 
ATOM   3918 O O     . SER B 2 327 ? 125.606 141.759 112.830 1.00 7.20   ? 316 SER B O     1 
ATOM   3919 C CB    . SER B 2 327 ? 127.541 141.754 115.452 1.00 0.93   ? 316 SER B CB    1 
ATOM   3920 O OG    . SER B 2 327 ? 127.828 140.425 115.846 1.00 0.00   ? 316 SER B OG    1 
ATOM   3921 N N     . CYS B 2 328 ? 125.399 139.870 114.027 1.00 5.88   ? 317 CYS B N     1 
ATOM   3922 C CA    . CYS B 2 328 ? 125.114 139.045 112.863 1.00 1.56   ? 317 CYS B CA    1 
ATOM   3923 C C     . CYS B 2 328 ? 123.887 138.186 113.128 1.00 2.74   ? 317 CYS B C     1 
ATOM   3924 O O     . CYS B 2 328 ? 123.636 137.768 114.260 1.00 2.66   ? 317 CYS B O     1 
ATOM   3925 C CB    . CYS B 2 328 ? 126.316 138.164 112.500 1.00 0.38   ? 317 CYS B CB    1 
ATOM   3926 S SG    . CYS B 2 328 ? 127.037 137.291 113.902 1.00 13.04  ? 317 CYS B SG    1 
ATOM   3927 N N     . LEU B 2 329 ? 123.129 137.924 112.067 1.00 6.36   ? 318 LEU B N     1 
ATOM   3928 C CA    . LEU B 2 329 ? 121.911 137.136 112.161 1.00 3.23   ? 318 LEU B CA    1 
ATOM   3929 C C     . LEU B 2 329 ? 121.780 136.283 110.909 1.00 4.68   ? 318 LEU B C     1 
ATOM   3930 O O     . LEU B 2 329 ? 122.067 136.746 109.802 1.00 8.12   ? 318 LEU B O     1 
ATOM   3931 C CB    . LEU B 2 329 ? 120.684 138.043 112.332 1.00 1.46   ? 318 LEU B CB    1 
ATOM   3932 C CG    . LEU B 2 329 ? 119.326 137.438 112.686 1.00 5.20   ? 318 LEU B CG    1 
ATOM   3933 C CD1   . LEU B 2 329 ? 118.525 138.465 113.450 1.00 8.52   ? 318 LEU B CD1   1 
ATOM   3934 C CD2   . LEU B 2 329 ? 118.561 136.996 111.455 1.00 7.01   ? 318 LEU B CD2   1 
ATOM   3935 N N     . GLY B 2 330 ? 121.349 135.043 111.089 1.00 0.84   ? 319 GLY B N     1 
ATOM   3936 C CA    . GLY B 2 330 ? 121.199 134.129 109.970 1.00 1.43   ? 319 GLY B CA    1 
ATOM   3937 C C     . GLY B 2 330 ? 120.065 133.161 110.205 1.00 1.29   ? 319 GLY B C     1 
ATOM   3938 O O     . GLY B 2 330 ? 119.713 132.853 111.347 1.00 5.61   ? 319 GLY B O     1 
ATOM   3939 N N     . VAL B 2 331 ? 119.485 132.680 109.109 1.00 1.49   ? 320 VAL B N     1 
ATOM   3940 C CA    . VAL B 2 331 ? 118.400 131.708 109.141 1.00 1.49   ? 320 VAL B CA    1 
ATOM   3941 C C     . VAL B 2 331 ? 118.806 130.511 108.293 1.00 1.25   ? 320 VAL B C     1 
ATOM   3942 O O     . VAL B 2 331 ? 119.344 130.675 107.193 1.00 1.73   ? 320 VAL B O     1 
ATOM   3943 C CB    . VAL B 2 331 ? 117.071 132.313 108.640 1.00 3.49   ? 320 VAL B CB    1 
ATOM   3944 C CG1   . VAL B 2 331 ? 115.952 131.285 108.714 1.00 0.83   ? 320 VAL B CG1   1 
ATOM   3945 C CG2   . VAL B 2 331 ? 116.711 133.549 109.448 1.00 5.22   ? 320 VAL B CG2   1 
ATOM   3946 N N     . THR B 2 332 ? 118.556 129.312 108.812 1.00 1.07   ? 321 THR B N     1 
ATOM   3947 C CA    . THR B 2 332 ? 118.932 128.094 108.112 1.00 0.12   ? 321 THR B CA    1 
ATOM   3948 C C     . THR B 2 332 ? 118.156 127.960 106.804 1.00 2.88   ? 321 THR B C     1 
ATOM   3949 O O     . THR B 2 332 ? 117.076 128.530 106.626 1.00 7.83   ? 321 THR B O     1 
ATOM   3950 C CB    . THR B 2 332 ? 118.681 126.867 108.988 1.00 0.22   ? 321 THR B CB    1 
ATOM   3951 O OG1   . THR B 2 332 ? 117.281 126.761 109.275 1.00 5.80   ? 321 THR B OG1   1 
ATOM   3952 C CG2   . THR B 2 332 ? 119.445 126.975 110.290 1.00 0.69   ? 321 THR B CG2   1 
ATOM   3953 N N     . ASP B 2 333 ? 118.731 127.191 105.874 1.00 2.69   ? 322 ASP B N     1 
ATOM   3954 C CA    . ASP B 2 333 ? 118.097 127.004 104.573 1.00 3.47   ? 322 ASP B CA    1 
ATOM   3955 C C     . ASP B 2 333 ? 116.748 126.307 104.693 1.00 5.85   ? 322 ASP B C     1 
ATOM   3956 O O     . ASP B 2 333 ? 115.871 126.508 103.845 1.00 10.82  ? 322 ASP B O     1 
ATOM   3957 C CB    . ASP B 2 333 ? 119.019 126.218 103.641 1.00 4.58   ? 322 ASP B CB    1 
ATOM   3958 C CG    . ASP B 2 333 ? 120.020 127.105 102.929 1.00 7.89   ? 322 ASP B CG    1 
ATOM   3959 O OD1   . ASP B 2 333 ? 119.747 128.314 102.783 1.00 4.99   ? 322 ASP B OD1   1 
ATOM   3960 O OD2   . ASP B 2 333 ? 121.074 126.591 102.504 1.00 7.32   ? 322 ASP B OD2   1 
ATOM   3961 N N     . ASP B 2 334 ? 116.561 125.488 105.724 1.00 1.92   ? 323 ASP B N     1 
ATOM   3962 C CA    . ASP B 2 334 ? 115.271 124.860 105.973 1.00 3.51   ? 323 ASP B CA    1 
ATOM   3963 C C     . ASP B 2 334 ? 114.396 125.669 106.921 1.00 6.03   ? 323 ASP B C     1 
ATOM   3964 O O     . ASP B 2 334 ? 113.301 125.216 107.269 1.00 5.07   ? 323 ASP B O     1 
ATOM   3965 C CB    . ASP B 2 334 ? 115.463 123.440 106.521 1.00 2.03   ? 323 ASP B CB    1 
ATOM   3966 C CG    . ASP B 2 334 ? 116.381 123.392 107.728 1.00 4.08   ? 323 ASP B CG    1 
ATOM   3967 O OD1   . ASP B 2 334 ? 116.714 124.461 108.276 1.00 4.89   ? 323 ASP B OD1   1 
ATOM   3968 O OD2   . ASP B 2 334 ? 116.769 122.276 108.132 1.00 8.06   ? 323 ASP B OD2   1 
ATOM   3969 N N     . GLY B 2 335 ? 114.853 126.845 107.350 1.00 6.69   ? 324 GLY B N     1 
ATOM   3970 C CA    . GLY B 2 335 ? 114.069 127.675 108.242 1.00 4.56   ? 324 GLY B CA    1 
ATOM   3971 C C     . GLY B 2 335 ? 113.855 127.090 109.615 1.00 5.45   ? 324 GLY B C     1 
ATOM   3972 O O     . GLY B 2 335 ? 112.918 127.491 110.310 1.00 8.91   ? 324 GLY B O     1 
ATOM   3973 N N     . MET B 2 336 ? 114.702 126.150 110.032 1.00 4.32   ? 325 MET B N     1 
ATOM   3974 C CA    . MET B 2 336 ? 114.482 125.451 111.292 1.00 2.89   ? 325 MET B CA    1 
ATOM   3975 C C     . MET B 2 336 ? 114.811 126.326 112.494 1.00 5.06   ? 325 MET B C     1 
ATOM   3976 O O     . MET B 2 336 ? 114.099 126.288 113.503 1.00 9.20   ? 325 MET B O     1 
ATOM   3977 C CB    . MET B 2 336 ? 115.309 124.167 111.325 1.00 5.12   ? 325 MET B CB    1 
ATOM   3978 C CG    . MET B 2 336 ? 114.825 123.148 112.337 1.00 7.86   ? 325 MET B CG    1 
ATOM   3979 S SD    . MET B 2 336 ? 113.283 122.360 111.837 1.00 17.74  ? 325 MET B SD    1 
ATOM   3980 C CE    . MET B 2 336 ? 112.230 122.783 113.221 1.00 7.04   ? 325 MET B CE    1 
ATOM   3981 N N     . ALA B 2 337 ? 115.876 127.120 112.411 1.00 4.47   ? 326 ALA B N     1 
ATOM   3982 C CA    . ALA B 2 337 ? 116.324 127.905 113.551 1.00 3.61   ? 326 ALA B CA    1 
ATOM   3983 C C     . ALA B 2 337 ? 116.980 129.185 113.059 1.00 2.97   ? 326 ALA B C     1 
ATOM   3984 O O     . ALA B 2 337 ? 117.325 129.322 111.882 1.00 2.05   ? 326 ALA B O     1 
ATOM   3985 C CB    . ALA B 2 337 ? 117.288 127.106 114.431 1.00 2.97   ? 326 ALA B CB    1 
ATOM   3986 N N     . VAL B 2 338 ? 117.147 130.131 113.980 1.00 3.32   ? 327 VAL B N     1 
ATOM   3987 C CA    . VAL B 2 338 ? 117.780 131.414 113.696 1.00 0.00   ? 327 VAL B CA    1 
ATOM   3988 C C     . VAL B 2 338 ? 118.997 131.561 114.597 1.00 0.79   ? 327 VAL B C     1 
ATOM   3989 O O     . VAL B 2 338 ? 118.883 131.455 115.821 1.00 4.09   ? 327 VAL B O     1 
ATOM   3990 C CB    . VAL B 2 338 ? 116.806 132.588 113.909 1.00 6.25   ? 327 VAL B CB    1 
ATOM   3991 C CG1   . VAL B 2 338 ? 117.532 133.915 113.757 1.00 4.73   ? 327 VAL B CG1   1 
ATOM   3992 C CG2   . VAL B 2 338 ? 115.652 132.497 112.936 1.00 8.41   ? 327 VAL B CG2   1 
ATOM   3993 N N     . ALA B 2 339 ? 120.153 131.812 113.996 1.00 3.22   ? 328 ALA B N     1 
ATOM   3994 C CA    . ALA B 2 339 ? 121.377 132.056 114.744 1.00 2.21   ? 328 ALA B CA    1 
ATOM   3995 C C     . ALA B 2 339 ? 121.594 133.557 114.873 1.00 2.18   ? 328 ALA B C     1 
ATOM   3996 O O     . ALA B 2 339 ? 121.468 134.294 113.890 1.00 2.41   ? 328 ALA B O     1 
ATOM   3997 C CB    . ALA B 2 339 ? 122.581 131.404 114.064 1.00 0.90   ? 328 ALA B CB    1 
ATOM   3998 N N     . THR B 2 340 ? 121.897 134.006 116.089 1.00 1.32   ? 329 THR B N     1 
ATOM   3999 C CA    . THR B 2 340 ? 122.219 135.402 116.356 1.00 2.65   ? 329 THR B CA    1 
ATOM   4000 C C     . THR B 2 340 ? 123.558 135.454 117.070 1.00 3.61   ? 329 THR B C     1 
ATOM   4001 O O     . THR B 2 340 ? 123.711 134.873 118.149 1.00 8.00   ? 329 THR B O     1 
ATOM   4002 C CB    . THR B 2 340 ? 121.137 136.081 117.202 1.00 2.71   ? 329 THR B CB    1 
ATOM   4003 O OG1   . THR B 2 340 ? 121.050 135.438 118.479 1.00 4.19   ? 329 THR B OG1   1 
ATOM   4004 C CG2   . THR B 2 340 ? 119.785 136.009 116.509 1.00 4.58   ? 329 THR B CG2   1 
ATOM   4005 N N     . GLY B 2 341 ? 124.526 136.136 116.463 1.00 2.43   ? 330 GLY B N     1 
ATOM   4006 C CA    . GLY B 2 341 ? 125.815 136.368 117.084 1.00 2.70   ? 330 GLY B CA    1 
ATOM   4007 C C     . GLY B 2 341 ? 125.930 137.824 117.496 1.00 3.84   ? 330 GLY B C     1 
ATOM   4008 O O     . GLY B 2 341 ? 125.661 138.730 116.702 1.00 5.33   ? 330 GLY B O     1 
ATOM   4009 N N     . SER B 2 342 ? 126.332 138.034 118.742 1.00 3.29   ? 331 SER B N     1 
ATOM   4010 C CA    . SER B 2 342 ? 126.372 139.358 119.337 1.00 5.25   ? 331 SER B CA    1 
ATOM   4011 C C     . SER B 2 342 ? 127.790 139.704 119.770 1.00 5.82   ? 331 SER B C     1 
ATOM   4012 O O     . SER B 2 342 ? 128.699 138.871 119.745 1.00 4.44   ? 331 SER B O     1 
ATOM   4013 C CB    . SER B 2 342 ? 125.414 139.451 120.531 1.00 5.50   ? 331 SER B CB    1 
ATOM   4014 O OG    . SER B 2 342 ? 125.615 140.651 121.252 1.00 5.90   ? 331 SER B OG    1 
ATOM   4015 N N     . TRP B 2 343 ? 127.965 140.964 120.171 1.00 6.70   ? 332 TRP B N     1 
ATOM   4016 C CA    . TRP B 2 343 ? 129.255 141.443 120.646 1.00 3.21   ? 332 TRP B CA    1 
ATOM   4017 C C     . TRP B 2 343 ? 129.626 140.880 122.011 1.00 6.61   ? 332 TRP B C     1 
ATOM   4018 O O     . TRP B 2 343 ? 130.769 141.059 122.444 1.00 10.07  ? 332 TRP B O     1 
ATOM   4019 C CB    . TRP B 2 343 ? 129.256 142.971 120.696 1.00 2.66   ? 332 TRP B CB    1 
ATOM   4020 C CG    . TRP B 2 343 ? 129.490 143.613 119.364 1.00 6.13   ? 332 TRP B CG    1 
ATOM   4021 C CD1   . TRP B 2 343 ? 129.571 142.986 118.156 1.00 5.98   ? 332 TRP B CD1   1 
ATOM   4022 C CD2   . TRP B 2 343 ? 129.671 145.010 119.103 1.00 6.46   ? 332 TRP B CD2   1 
ATOM   4023 N NE1   . TRP B 2 343 ? 129.793 143.904 117.159 1.00 2.02   ? 332 TRP B NE1   1 
ATOM   4024 C CE2   . TRP B 2 343 ? 129.858 145.154 117.715 1.00 4.37   ? 332 TRP B CE2   1 
ATOM   4025 C CE3   . TRP B 2 343 ? 129.694 146.151 119.909 1.00 4.18   ? 332 TRP B CE3   1 
ATOM   4026 C CZ2   . TRP B 2 343 ? 130.065 146.393 117.115 1.00 2.82   ? 332 TRP B CZ2   1 
ATOM   4027 C CZ3   . TRP B 2 343 ? 129.899 147.380 119.312 1.00 4.32   ? 332 TRP B CZ3   1 
ATOM   4028 C CH2   . TRP B 2 343 ? 130.082 147.492 117.928 1.00 4.17   ? 332 TRP B CH2   1 
ATOM   4029 N N     . ASP B 2 344 ? 128.698 140.211 122.694 1.00 3.93   ? 333 ASP B N     1 
ATOM   4030 C CA    . ASP B 2 344 ? 128.974 139.588 123.982 1.00 5.40   ? 333 ASP B CA    1 
ATOM   4031 C C     . ASP B 2 344 ? 129.727 138.268 123.855 1.00 3.90   ? 333 ASP B C     1 
ATOM   4032 O O     . ASP B 2 344 ? 129.858 137.554 124.856 1.00 6.84   ? 333 ASP B O     1 
ATOM   4033 C CB    . ASP B 2 344 ? 127.668 139.377 124.756 1.00 4.88   ? 333 ASP B CB    1 
ATOM   4034 C CG    . ASP B 2 344 ? 126.709 138.436 124.050 1.00 10.93  ? 333 ASP B CG    1 
ATOM   4035 O OD1   . ASP B 2 344 ? 126.979 138.054 122.893 1.00 12.75  ? 333 ASP B OD1   1 
ATOM   4036 O OD2   . ASP B 2 344 ? 125.678 138.077 124.656 1.00 12.63  ? 333 ASP B OD2   1 
ATOM   4037 N N     . SER B 2 345 ? 130.202 137.932 122.652 1.00 0.79   ? 334 SER B N     1 
ATOM   4038 C CA    . SER B 2 345 ? 131.033 136.755 122.395 1.00 3.81   ? 334 SER B CA    1 
ATOM   4039 C C     . SER B 2 345 ? 130.259 135.448 122.541 1.00 3.97   ? 334 SER B C     1 
ATOM   4040 O O     . SER B 2 345 ? 130.808 134.446 123.003 1.00 6.57   ? 334 SER B O     1 
ATOM   4041 C CB    . SER B 2 345 ? 132.276 136.736 123.291 1.00 7.01   ? 334 SER B CB    1 
ATOM   4042 O OG    . SER B 2 345 ? 131.949 136.356 124.617 1.00 11.08  ? 334 SER B OG    1 
ATOM   4043 N N     . PHE B 2 346 ? 128.989 135.434 122.140 1.00 1.50   ? 335 PHE B N     1 
ATOM   4044 C CA    . PHE B 2 346 ? 128.183 134.222 122.172 1.00 5.07   ? 335 PHE B CA    1 
ATOM   4045 C C     . PHE B 2 346 ? 127.262 134.181 120.963 1.00 6.52   ? 335 PHE B C     1 
ATOM   4046 O O     . PHE B 2 346 ? 126.739 135.209 120.526 1.00 9.96   ? 335 PHE B O     1 
ATOM   4047 C CB    . PHE B 2 346 ? 127.343 134.124 123.455 1.00 6.04   ? 335 PHE B CB    1 
ATOM   4048 C CG    . PHE B 2 346 ? 128.157 134.073 124.713 1.00 6.52   ? 335 PHE B CG    1 
ATOM   4049 C CD1   . PHE B 2 346 ? 128.940 132.971 125.004 1.00 6.15   ? 335 PHE B CD1   1 
ATOM   4050 C CD2   . PHE B 2 346 ? 128.133 135.128 125.609 1.00 6.11   ? 335 PHE B CD2   1 
ATOM   4051 C CE1   . PHE B 2 346 ? 129.690 132.924 126.162 1.00 6.24   ? 335 PHE B CE1   1 
ATOM   4052 C CE2   . PHE B 2 346 ? 128.882 135.086 126.767 1.00 6.53   ? 335 PHE B CE2   1 
ATOM   4053 C CZ    . PHE B 2 346 ? 129.660 133.982 127.044 1.00 6.33   ? 335 PHE B CZ    1 
ATOM   4054 N N     . LEU B 2 347 ? 127.068 132.979 120.427 1.00 6.06   ? 336 LEU B N     1 
ATOM   4055 C CA    . LEU B 2 347 ? 126.038 132.725 119.430 1.00 2.88   ? 336 LEU B CA    1 
ATOM   4056 C C     . LEU B 2 347 ? 124.865 132.028 120.100 1.00 3.91   ? 336 LEU B C     1 
ATOM   4057 O O     . LEU B 2 347 ? 125.052 131.106 120.899 1.00 8.75   ? 336 LEU B O     1 
ATOM   4058 C CB    . LEU B 2 347 ? 126.547 131.854 118.278 1.00 1.60   ? 336 LEU B CB    1 
ATOM   4059 C CG    . LEU B 2 347 ? 127.429 132.442 117.175 1.00 3.40   ? 336 LEU B CG    1 
ATOM   4060 C CD1   . LEU B 2 347 ? 128.844 132.632 117.666 1.00 3.52   ? 336 LEU B CD1   1 
ATOM   4061 C CD2   . LEU B 2 347 ? 127.403 131.571 115.934 1.00 6.63   ? 336 LEU B CD2   1 
ATOM   4062 N N     . LYS B 2 348 ? 123.655 132.471 119.775 1.00 1.44   ? 337 LYS B N     1 
ATOM   4063 C CA    . LYS B 2 348 ? 122.446 131.867 120.312 1.00 2.69   ? 337 LYS B CA    1 
ATOM   4064 C C     . LYS B 2 348 ? 121.570 131.393 119.165 1.00 3.99   ? 337 LYS B C     1 
ATOM   4065 O O     . LYS B 2 348 ? 121.296 132.152 118.230 1.00 2.07   ? 337 LYS B O     1 
ATOM   4066 C CB    . LYS B 2 348 ? 121.680 132.849 121.203 1.00 6.51   ? 337 LYS B CB    1 
ATOM   4067 C CG    . LYS B 2 348 ? 122.355 133.103 122.540 1.00 5.82   ? 337 LYS B CG    1 
ATOM   4068 C CD    . LYS B 2 348 ? 121.435 133.823 123.504 1.00 6.54   ? 337 LYS B CD    1 
ATOM   4069 C CE    . LYS B 2 348 ? 122.041 133.878 124.894 1.00 3.50   ? 337 LYS B CE    1 
ATOM   4070 N NZ    . LYS B 2 348 ? 121.060 134.355 125.907 1.00 8.11   ? 337 LYS B NZ    1 
ATOM   4071 N N     . ILE B 2 349 ? 121.144 130.137 119.236 1.00 5.95   ? 338 ILE B N     1 
ATOM   4072 C CA    . ILE B 2 349 ? 120.235 129.547 118.263 1.00 2.56   ? 338 ILE B CA    1 
ATOM   4073 C C     . ILE B 2 349 ? 118.834 129.574 118.854 1.00 5.69   ? 338 ILE B C     1 
ATOM   4074 O O     . ILE B 2 349 ? 118.640 129.221 120.022 1.00 9.98   ? 338 ILE B O     1 
ATOM   4075 C CB    . ILE B 2 349 ? 120.667 128.117 117.896 1.00 3.66   ? 338 ILE B CB    1 
ATOM   4076 C CG1   . ILE B 2 349 ? 121.884 128.158 116.971 1.00 2.99   ? 338 ILE B CG1   1 
ATOM   4077 C CG2   . ILE B 2 349 ? 119.526 127.357 117.247 1.00 5.83   ? 338 ILE B CG2   1 
ATOM   4078 C CD1   . ILE B 2 349 ? 122.825 126.995 117.145 1.00 5.59   ? 338 ILE B CD1   1 
ATOM   4079 N N     . TRP B 2 350 ? 117.866 130.018 118.060 1.00 6.27   ? 339 TRP B N     1 
ATOM   4080 C CA    . TRP B 2 350 ? 116.493 130.205 118.501 1.00 6.44   ? 339 TRP B CA    1 
ATOM   4081 C C     . TRP B 2 350 ? 115.564 129.368 117.636 1.00 8.84   ? 339 TRP B C     1 
ATOM   4082 O O     . TRP B 2 350 ? 115.734 129.298 116.413 1.00 12.60  ? 339 TRP B O     1 
ATOM   4083 C CB    . TRP B 2 350 ? 116.082 131.680 118.426 1.00 5.97   ? 339 TRP B CB    1 
ATOM   4084 C CG    . TRP B 2 350 ? 117.093 132.625 119.000 1.00 2.70   ? 339 TRP B CG    1 
ATOM   4085 C CD1   . TRP B 2 350 ? 118.284 132.990 118.444 1.00 2.02   ? 339 TRP B CD1   1 
ATOM   4086 C CD2   . TRP B 2 350 ? 116.996 133.334 120.239 1.00 8.60   ? 339 TRP B CD2   1 
ATOM   4087 N NE1   . TRP B 2 350 ? 118.937 133.877 119.262 1.00 4.64   ? 339 TRP B NE1   1 
ATOM   4088 C CE2   . TRP B 2 350 ? 118.167 134.105 120.371 1.00 7.79   ? 339 TRP B CE2   1 
ATOM   4089 C CE3   . TRP B 2 350 ? 116.033 133.391 121.250 1.00 5.69   ? 339 TRP B CE3   1 
ATOM   4090 C CZ2   . TRP B 2 350 ? 118.400 134.923 121.473 1.00 5.96   ? 339 TRP B CZ2   1 
ATOM   4091 C CZ3   . TRP B 2 350 ? 116.267 134.202 122.342 1.00 5.90   ? 339 TRP B CZ3   1 
ATOM   4092 C CH2   . TRP B 2 350 ? 117.441 134.956 122.445 1.00 7.46   ? 339 TRP B CH2   1 
ATOM   4093 N N     . ASN B 2 351 ? 114.582 128.743 118.277 1.00 10.40  ? 340 ASN B N     1 
ATOM   4094 C CA    . ASN B 2 351 ? 113.628 127.894 117.576 1.00 10.40  ? 340 ASN B CA    1 
ATOM   4095 C C     . ASN B 2 351 ? 112.244 127.983 118.209 1.00 10.24  ? 340 ASN B C     1 
ATOM   4096 O O     . ASN B 2 351 ? 112.019 128.778 119.120 1.00 12.16  ? 340 ASN B O     1 
ATOM   4097 C CB    . ASN B 2 351 ? 114.113 126.443 117.568 1.00 10.09  ? 340 ASN B CB    1 
ATOM   4098 C CG    . ASN B 2 351 ? 113.507 125.633 116.442 1.00 12.81  ? 340 ASN B CG    1 
ATOM   4099 O OD1   . ASN B 2 351 ? 112.527 126.046 115.823 1.00 12.29  ? 340 ASN B OD1   1 
ATOM   4100 N ND2   . ASN B 2 351 ? 114.093 124.476 116.166 1.00 10.75  ? 340 ASN B ND2   1 
ATOM   4101 N N     . ALA C 3 7   ? 137.806 164.608 84.271  1.00 83.37  ? 7   ALA G N     1 
ATOM   4102 C CA    . ALA C 3 7   ? 137.464 163.667 85.330  1.00 85.74  ? 7   ALA G CA    1 
ATOM   4103 C C     . ALA C 3 7   ? 136.007 163.830 85.753  1.00 86.01  ? 7   ALA G C     1 
ATOM   4104 O O     . ALA C 3 7   ? 135.243 162.864 85.763  1.00 82.43  ? 7   ALA G O     1 
ATOM   4105 C CB    . ALA C 3 7   ? 138.387 163.854 86.524  1.00 84.52  ? 7   ALA G CB    1 
ATOM   4106 N N     . SER C 3 8   ? 135.633 165.061 86.107  1.00 85.42  ? 8   SER G N     1 
ATOM   4107 C CA    . SER C 3 8   ? 134.256 165.331 86.509  1.00 83.94  ? 8   SER G CA    1 
ATOM   4108 C C     . SER C 3 8   ? 133.288 165.118 85.352  1.00 82.86  ? 8   SER G C     1 
ATOM   4109 O O     . SER C 3 8   ? 132.183 164.600 85.548  1.00 81.83  ? 8   SER G O     1 
ATOM   4110 C CB    . SER C 3 8   ? 134.138 166.754 87.054  1.00 82.00  ? 8   SER G CB    1 
ATOM   4111 N N     . ILE C 3 9   ? 133.683 165.520 84.141  1.00 78.25  ? 9   ILE G N     1 
ATOM   4112 C CA    . ILE C 3 9   ? 132.812 165.357 82.980  1.00 78.45  ? 9   ILE G CA    1 
ATOM   4113 C C     . ILE C 3 9   ? 132.557 163.881 82.703  1.00 79.28  ? 9   ILE G C     1 
ATOM   4114 O O     . ILE C 3 9   ? 131.424 163.475 82.417  1.00 78.86  ? 9   ILE G O     1 
ATOM   4115 C CB    . ILE C 3 9   ? 133.417 166.066 81.754  1.00 76.62  ? 9   ILE G CB    1 
ATOM   4116 N N     . ALA C 3 10  ? 133.605 163.057 82.777  1.00 76.93  ? 10  ALA G N     1 
ATOM   4117 C CA    . ALA C 3 10  ? 133.440 161.627 82.534  1.00 76.47  ? 10  ALA G CA    1 
ATOM   4118 C C     . ALA C 3 10  ? 132.542 160.985 83.585  1.00 76.70  ? 10  ALA G C     1 
ATOM   4119 O O     . ALA C 3 10  ? 131.685 160.156 83.257  1.00 74.84  ? 10  ALA G O     1 
ATOM   4120 C CB    . ALA C 3 10  ? 134.805 160.939 82.501  1.00 75.37  ? 10  ALA G CB    1 
ATOM   4121 N N     . GLN C 3 11  ? 132.725 161.355 84.855  1.00 75.68  ? 11  GLN G N     1 
ATOM   4122 C CA    . GLN C 3 11  ? 131.880 160.808 85.913  1.00 73.83  ? 11  GLN G CA    1 
ATOM   4123 C C     . GLN C 3 11  ? 130.427 161.229 85.732  1.00 74.95  ? 11  GLN G C     1 
ATOM   4124 O O     . GLN C 3 11  ? 129.511 160.421 85.923  1.00 74.90  ? 11  GLN G O     1 
ATOM   4125 C CB    . GLN C 3 11  ? 132.401 161.249 87.281  1.00 72.33  ? 11  GLN G CB    1 
ATOM   4126 N N     . ALA C 3 12  ? 130.197 162.492 85.363  1.00 70.98  ? 12  ALA G N     1 
ATOM   4127 C CA    . ALA C 3 12  ? 128.834 162.957 85.131  1.00 69.49  ? 12  ALA G CA    1 
ATOM   4128 C C     . ALA C 3 12  ? 128.197 162.233 83.952  1.00 69.23  ? 12  ALA G C     1 
ATOM   4129 O O     . ALA C 3 12  ? 127.016 161.869 84.002  1.00 71.67  ? 12  ALA G O     1 
ATOM   4130 C CB    . ALA C 3 12  ? 128.826 164.468 84.907  1.00 69.35  ? 12  ALA G CB    1 
ATOM   4131 N N     . ARG C 3 13  ? 128.962 162.016 82.879  1.00 65.06  ? 13  ARG G N     1 
ATOM   4132 C CA    . ARG C 3 13  ? 128.436 161.285 81.731  1.00 66.23  ? 13  ARG G CA    1 
ATOM   4133 C C     . ARG C 3 13  ? 128.105 159.844 82.099  1.00 68.33  ? 13  ARG G C     1 
ATOM   4134 O O     . ARG C 3 13  ? 127.078 159.306 81.669  1.00 67.03  ? 13  ARG G O     1 
ATOM   4135 C CB    . ARG C 3 13  ? 129.437 161.329 80.577  1.00 64.13  ? 13  ARG G CB    1 
ATOM   4136 N N     . LYS C 3 14  ? 128.967 159.202 82.891  1.00 63.54  ? 14  LYS G N     1 
ATOM   4137 C CA    . LYS C 3 14  ? 128.691 157.838 83.333  1.00 60.34  ? 14  LYS G CA    1 
ATOM   4138 C C     . LYS C 3 14  ? 127.441 157.783 84.201  1.00 60.64  ? 14  LYS G C     1 
ATOM   4139 O O     . LYS C 3 14  ? 126.624 156.865 84.069  1.00 60.78  ? 14  LYS G O     1 
ATOM   4140 C CB    . LYS C 3 14  ? 129.896 157.277 84.088  1.00 60.81  ? 14  LYS G CB    1 
ATOM   4141 N N     . LEU C 3 15  ? 127.276 158.759 85.098  1.00 58.14  ? 15  LEU G N     1 
ATOM   4142 C CA    . LEU C 3 15  ? 126.080 158.801 85.934  1.00 58.05  ? 15  LEU G CA    1 
ATOM   4143 C C     . LEU C 3 15  ? 124.827 159.013 85.094  1.00 56.08  ? 15  LEU G C     1 
ATOM   4144 O O     . LEU C 3 15  ? 123.787 158.397 85.351  1.00 57.52  ? 15  LEU G O     1 
ATOM   4145 C CB    . LEU C 3 15  ? 126.215 159.901 86.988  1.00 53.56  ? 15  LEU G CB    1 
ATOM   4146 N N     . VAL C 3 16  ? 124.908 159.884 84.086  1.00 52.97  ? 16  VAL G N     1 
ATOM   4147 C CA    . VAL C 3 16  ? 123.767 160.116 83.204  1.00 50.77  ? 16  VAL G CA    1 
ATOM   4148 C C     . VAL C 3 16  ? 123.417 158.847 82.438  1.00 52.38  ? 16  VAL G C     1 
ATOM   4149 O O     . VAL C 3 16  ? 122.240 158.495 82.294  1.00 56.61  ? 16  VAL G O     1 
ATOM   4150 C CB    . VAL C 3 16  ? 124.059 161.293 82.255  1.00 53.99  ? 16  VAL G CB    1 
ATOM   4151 C CG1   . VAL C 3 16  ? 123.124 161.265 81.055  1.00 53.05  ? 16  VAL G CG1   1 
ATOM   4152 C CG2   . VAL C 3 16  ? 123.938 162.613 82.998  1.00 55.83  ? 16  VAL G CG2   1 
ATOM   4153 N N     . GLU C 3 17  ? 124.432 158.141 81.932  1.00 51.50  ? 17  GLU G N     1 
ATOM   4154 C CA    . GLU C 3 17  ? 124.182 156.895 81.213  1.00 50.63  ? 17  GLU G CA    1 
ATOM   4155 C C     . GLU C 3 17  ? 123.556 155.846 82.125  1.00 51.75  ? 17  GLU G C     1 
ATOM   4156 O O     . GLU C 3 17  ? 122.637 155.127 81.716  1.00 52.37  ? 17  GLU G O     1 
ATOM   4157 C CB    . GLU C 3 17  ? 125.482 156.371 80.604  1.00 51.13  ? 17  GLU G CB    1 
ATOM   4158 N N     . GLN C 3 18  ? 124.044 155.742 83.364  1.00 48.91  ? 18  GLN G N     1 
ATOM   4159 C CA    . GLN C 3 18  ? 123.467 154.793 84.312  1.00 46.46  ? 18  GLN G CA    1 
ATOM   4160 C C     . GLN C 3 18  ? 122.016 155.141 84.626  1.00 46.59  ? 18  GLN G C     1 
ATOM   4161 O O     . GLN C 3 18  ? 121.157 154.253 84.694  1.00 50.81  ? 18  GLN G O     1 
ATOM   4162 C CB    . GLN C 3 18  ? 124.304 154.760 85.591  1.00 46.90  ? 18  GLN G CB    1 
ATOM   4163 C CG    . GLN C 3 18  ? 123.630 154.074 86.768  1.00 47.19  ? 18  GLN G CG    1 
ATOM   4164 C CD    . GLN C 3 18  ? 123.313 152.618 86.494  1.00 48.07  ? 18  GLN G CD    1 
ATOM   4165 O OE1   . GLN C 3 18  ? 122.205 152.152 86.758  1.00 48.58  ? 18  GLN G OE1   1 
ATOM   4166 N NE2   . GLN C 3 18  ? 124.288 151.890 85.963  1.00 49.17  ? 18  GLN G NE2   1 
ATOM   4167 N N     . LEU C 3 19  ? 121.725 156.429 84.820  1.00 41.77  ? 19  LEU G N     1 
ATOM   4168 C CA    . LEU C 3 19  ? 120.352 156.848 85.085  1.00 39.75  ? 19  LEU G CA    1 
ATOM   4169 C C     . LEU C 3 19  ? 119.446 156.551 83.897  1.00 41.11  ? 19  LEU G C     1 
ATOM   4170 O O     . LEU C 3 19  ? 118.301 156.121 84.073  1.00 45.73  ? 19  LEU G O     1 
ATOM   4171 C CB    . LEU C 3 19  ? 120.315 158.335 85.432  1.00 41.22  ? 19  LEU G CB    1 
ATOM   4172 C CG    . LEU C 3 19  ? 120.677 158.694 86.873  1.00 41.72  ? 19  LEU G CG    1 
ATOM   4173 C CD1   . LEU C 3 19  ? 120.689 160.202 87.064  1.00 44.99  ? 19  LEU G CD1   1 
ATOM   4174 C CD2   . LEU C 3 19  ? 119.712 158.035 87.846  1.00 40.09  ? 19  LEU G CD2   1 
ATOM   4175 N N     . LYS C 3 20  ? 119.938 156.783 82.678  1.00 43.07  ? 20  LYS G N     1 
ATOM   4176 C CA    . LYS C 3 20  ? 119.148 156.476 81.490  1.00 44.66  ? 20  LYS G CA    1 
ATOM   4177 C C     . LYS C 3 20  ? 118.889 154.979 81.374  1.00 47.05  ? 20  LYS G C     1 
ATOM   4178 O O     . LYS C 3 20  ? 117.784 154.559 81.011  1.00 47.69  ? 20  LYS G O     1 
ATOM   4179 C CB    . LYS C 3 20  ? 119.854 156.999 80.240  1.00 42.34  ? 20  LYS G CB    1 
ATOM   4180 N N     . MET C 3 21  ? 119.899 154.159 81.671  1.00 47.56  ? 21  MET G N     1 
ATOM   4181 C CA    . MET C 3 21  ? 119.720 152.712 81.620  1.00 45.52  ? 21  MET G CA    1 
ATOM   4182 C C     . MET C 3 21  ? 118.721 152.238 82.669  1.00 46.65  ? 21  MET G C     1 
ATOM   4183 O O     . MET C 3 21  ? 117.920 151.334 82.407  1.00 47.94  ? 21  MET G O     1 
ATOM   4184 C CB    . MET C 3 21  ? 121.066 152.010 81.803  1.00 43.81  ? 21  MET G CB    1 
ATOM   4185 N N     . GLU C 3 22  ? 118.759 152.827 83.864  1.00 43.70  ? 22  GLU G N     1 
ATOM   4186 C CA    . GLU C 3 22  ? 117.830 152.441 84.919  1.00 43.81  ? 22  GLU G CA    1 
ATOM   4187 C C     . GLU C 3 22  ? 116.433 153.013 84.718  1.00 43.98  ? 22  GLU G C     1 
ATOM   4188 O O     . GLU C 3 22  ? 115.479 152.507 85.319  1.00 40.74  ? 22  GLU G O     1 
ATOM   4189 C CB    . GLU C 3 22  ? 118.371 152.880 86.282  1.00 35.84  ? 22  GLU G CB    1 
ATOM   4190 N N     . ALA C 3 23  ? 116.290 154.053 83.894  1.00 42.78  ? 23  ALA G N     1 
ATOM   4191 C CA    . ALA C 3 23  ? 114.996 154.707 83.728  1.00 42.25  ? 23  ALA G CA    1 
ATOM   4192 C C     . ALA C 3 23  ? 114.056 153.913 82.829  1.00 45.78  ? 23  ALA G C     1 
ATOM   4193 O O     . ALA C 3 23  ? 112.841 153.905 83.056  1.00 44.73  ? 23  ALA G O     1 
ATOM   4194 C CB    . ALA C 3 23  ? 115.192 156.117 83.171  1.00 39.74  ? 23  ALA G CB    1 
ATOM   4195 N N     . ASN C 3 24  ? 114.588 153.241 81.811  1.00 46.63  ? 24  ASN G N     1 
ATOM   4196 C CA    . ASN C 3 24  ? 113.765 152.609 80.788  1.00 48.02  ? 24  ASN G CA    1 
ATOM   4197 C C     . ASN C 3 24  ? 113.361 151.181 81.138  1.00 48.34  ? 24  ASN G C     1 
ATOM   4198 O O     . ASN C 3 24  ? 112.752 150.504 80.303  1.00 51.50  ? 24  ASN G O     1 
ATOM   4199 C CB    . ASN C 3 24  ? 114.488 152.634 79.436  1.00 47.67  ? 24  ASN G CB    1 
ATOM   4200 C CG    . ASN C 3 24  ? 115.883 152.039 79.501  1.00 50.07  ? 24  ASN G CG    1 
ATOM   4201 O OD1   . ASN C 3 24  ? 116.153 151.132 80.286  1.00 48.77  ? 24  ASN G OD1   1 
ATOM   4202 N ND2   . ASN C 3 24  ? 116.780 152.553 78.668  1.00 48.23  ? 24  ASN G ND2   1 
ATOM   4203 N N     . ILE C 3 25  ? 113.690 150.706 82.340  1.00 40.08  ? 25  ILE G N     1 
ATOM   4204 C CA    . ILE C 3 25  ? 113.302 149.359 82.737  1.00 39.85  ? 25  ILE G CA    1 
ATOM   4205 C C     . ILE C 3 25  ? 111.785 149.276 82.865  1.00 40.93  ? 25  ILE G C     1 
ATOM   4206 O O     . ILE C 3 25  ? 111.099 150.274 83.127  1.00 40.35  ? 25  ILE G O     1 
ATOM   4207 C CB    . ILE C 3 25  ? 113.992 148.955 84.053  1.00 39.64  ? 25  ILE G CB    1 
ATOM   4208 C CG1   . ILE C 3 25  ? 113.428 149.760 85.226  1.00 37.67  ? 25  ILE G CG1   1 
ATOM   4209 C CG2   . ILE C 3 25  ? 115.497 149.146 83.946  1.00 40.97  ? 25  ILE G CG2   1 
ATOM   4210 C CD1   . ILE C 3 25  ? 113.986 149.352 86.569  1.00 39.34  ? 25  ILE G CD1   1 
ATOM   4211 N N     . ASP C 3 26  ? 111.252 148.073 82.667  1.00 41.57  ? 26  ASP G N     1 
ATOM   4212 C CA    . ASP C 3 26  ? 109.817 147.835 82.758  1.00 41.40  ? 26  ASP G CA    1 
ATOM   4213 C C     . ASP C 3 26  ? 109.446 147.580 84.213  1.00 41.18  ? 26  ASP G C     1 
ATOM   4214 O O     . ASP C 3 26  ? 110.000 146.680 84.853  1.00 41.64  ? 26  ASP G O     1 
ATOM   4215 C CB    . ASP C 3 26  ? 109.408 146.654 81.880  1.00 39.60  ? 26  ASP G CB    1 
ATOM   4216 N N     . ARG C 3 27  ? 108.510 148.369 84.732  1.00 31.77  ? 27  ARG G N     1 
ATOM   4217 C CA    . ARG C 3 27  ? 108.073 148.273 86.117  1.00 30.21  ? 27  ARG G CA    1 
ATOM   4218 C C     . ARG C 3 27  ? 106.627 147.803 86.166  1.00 29.90  ? 27  ARG G C     1 
ATOM   4219 O O     . ARG C 3 27  ? 105.781 148.307 85.420  1.00 28.82  ? 27  ARG G O     1 
ATOM   4220 C CB    . ARG C 3 27  ? 108.208 149.619 86.832  1.00 27.61  ? 27  ARG G CB    1 
ATOM   4221 C CG    . ARG C 3 27  ? 109.625 150.160 86.909  1.00 31.73  ? 27  ARG G CG    1 
ATOM   4222 C CD    . ARG C 3 27  ? 109.643 151.527 87.574  1.00 29.30  ? 27  ARG G CD    1 
ATOM   4223 N NE    . ARG C 3 27  ? 110.988 152.083 87.661  1.00 33.43  ? 27  ARG G NE    1 
ATOM   4224 C CZ    . ARG C 3 27  ? 111.596 152.732 86.678  1.00 33.01  ? 27  ARG G CZ    1 
ATOM   4225 N NH1   . ARG C 3 27  ? 111.006 152.929 85.511  1.00 31.88  ? 27  ARG G NH1   1 
ATOM   4226 N NH2   . ARG C 3 27  ? 112.827 153.196 86.871  1.00 33.43  ? 27  ARG G NH2   1 
ATOM   4227 N N     . ILE C 3 28  ? 106.350 146.843 87.039  1.00 27.01  ? 28  ILE G N     1 
ATOM   4228 C CA    . ILE C 3 28  ? 104.992 146.375 87.259  1.00 25.40  ? 28  ILE G CA    1 
ATOM   4229 C C     . ILE C 3 28  ? 104.353 147.214 88.358  1.00 24.85  ? 28  ILE G C     1 
ATOM   4230 O O     . ILE C 3 28  ? 105.028 147.922 89.109  1.00 26.31  ? 28  ILE G O     1 
ATOM   4231 C CB    . ILE C 3 28  ? 104.952 144.876 87.613  1.00 22.87  ? 28  ILE G CB    1 
ATOM   4232 C CG1   . ILE C 3 28  ? 105.362 144.663 89.071  1.00 22.65  ? 28  ILE G CG1   1 
ATOM   4233 C CG2   . ILE C 3 28  ? 105.856 144.085 86.681  1.00 26.21  ? 28  ILE G CG2   1 
ATOM   4234 C CD1   . ILE C 3 28  ? 105.229 143.236 89.537  1.00 17.94  ? 28  ILE G CD1   1 
ATOM   4235 N N     . LYS C 3 29  ? 103.029 147.140 88.446  1.00 25.30  ? 29  LYS G N     1 
ATOM   4236 C CA    . LYS C 3 29  ? 102.309 147.865 89.481  1.00 23.42  ? 29  LYS G CA    1 
ATOM   4237 C C     . LYS C 3 29  ? 102.675 147.332 90.861  1.00 18.59  ? 29  LYS G C     1 
ATOM   4238 O O     . LYS C 3 29  ? 102.955 146.144 91.041  1.00 28.28  ? 29  LYS G O     1 
ATOM   4239 C CB    . LYS C 3 29  ? 100.800 147.755 89.260  1.00 23.58  ? 29  LYS G CB    1 
ATOM   4240 C CG    . LYS C 3 29  ? 100.351 148.118 87.854  1.00 24.87  ? 29  LYS G CG    1 
ATOM   4241 C CD    . LYS C 3 29  ? 100.532 149.601 87.580  1.00 27.25  ? 29  LYS G CD    1 
ATOM   4242 C CE    . LYS C 3 29  ? 99.527  150.431 88.360  1.00 30.48  ? 29  LYS G CE    1 
ATOM   4243 N NZ    . LYS C 3 29  ? 99.470  151.838 87.877  1.00 29.35  ? 29  LYS G NZ    1 
ATOM   4244 N N     . VAL C 3 30  ? 102.680 148.236 91.844  1.00 16.23  ? 30  VAL G N     1 
ATOM   4245 C CA    . VAL C 3 30  ? 102.993 147.844 93.216  1.00 19.30  ? 30  VAL G CA    1 
ATOM   4246 C C     . VAL C 3 30  ? 101.955 146.864 93.743  1.00 20.96  ? 30  VAL G C     1 
ATOM   4247 O O     . VAL C 3 30  ? 102.281 145.963 94.524  1.00 24.91  ? 30  VAL G O     1 
ATOM   4248 C CB    . VAL C 3 30  ? 103.111 149.095 94.111  1.00 19.87  ? 30  VAL G CB    1 
ATOM   4249 C CG1   . VAL C 3 30  ? 103.140 148.711 95.582  1.00 16.79  ? 30  VAL G CG1   1 
ATOM   4250 C CG2   . VAL C 3 30  ? 104.358 149.876 93.751  1.00 26.26  ? 30  VAL G CG2   1 
ATOM   4251 N N     . SER C 3 31  ? 100.697 147.013 93.323  1.00 25.84  ? 31  SER G N     1 
ATOM   4252 C CA    . SER C 3 31  ? 99.660  146.080 93.751  1.00 21.02  ? 31  SER G CA    1 
ATOM   4253 C C     . SER C 3 31  ? 99.962  144.661 93.283  1.00 19.33  ? 31  SER G C     1 
ATOM   4254 O O     . SER C 3 31  ? 99.802  143.703 94.048  1.00 20.98  ? 31  SER G O     1 
ATOM   4255 C CB    . SER C 3 31  ? 98.296  146.536 93.234  1.00 25.17  ? 31  SER G CB    1 
ATOM   4256 O OG    . SER C 3 31  ? 98.249  146.496 91.819  1.00 36.65  ? 31  SER G OG    1 
ATOM   4257 N N     . LYS C 3 32  ? 100.400 144.504 92.031  1.00 23.04  ? 32  LYS G N     1 
ATOM   4258 C CA    . LYS C 3 32  ? 100.715 143.173 91.519  1.00 20.57  ? 32  LYS G CA    1 
ATOM   4259 C C     . LYS C 3 32  ? 101.900 142.557 92.254  1.00 23.64  ? 32  LYS G C     1 
ATOM   4260 O O     . LYS C 3 32  ? 101.877 141.367 92.594  1.00 27.13  ? 32  LYS G O     1 
ATOM   4261 C CB    . LYS C 3 32  ? 100.992 143.241 90.018  1.00 18.89  ? 32  LYS G CB    1 
ATOM   4262 N N     . ALA C 3 33  ? 102.947 143.347 92.500  1.00 19.47  ? 33  ALA G N     1 
ATOM   4263 C CA    . ALA C 3 33  ? 104.105 142.838 93.228  1.00 17.81  ? 33  ALA G CA    1 
ATOM   4264 C C     . ALA C 3 33  ? 103.731 142.445 94.651  1.00 19.02  ? 33  ALA G C     1 
ATOM   4265 O O     . ALA C 3 33  ? 104.177 141.408 95.157  1.00 28.02  ? 33  ALA G O     1 
ATOM   4266 C CB    . ALA C 3 33  ? 105.219 143.882 93.233  1.00 19.53  ? 33  ALA G CB    1 
ATOM   4267 N N     . ALA C 3 34  ? 102.907 143.261 95.311  1.00 16.61  ? 34  ALA G N     1 
ATOM   4268 C CA    . ALA C 3 34  ? 102.455 142.938 96.658  1.00 12.41  ? 34  ALA G CA    1 
ATOM   4269 C C     . ALA C 3 34  ? 101.606 141.674 96.667  1.00 15.44  ? 34  ALA G C     1 
ATOM   4270 O O     . ALA C 3 34  ? 101.719 140.847 97.580  1.00 23.58  ? 34  ALA G O     1 
ATOM   4271 C CB    . ALA C 3 34  ? 101.676 144.115 97.241  1.00 15.64  ? 34  ALA G CB    1 
ATOM   4272 N N     . ALA C 3 35  ? 100.740 141.513 95.664  1.00 19.23  ? 35  ALA G N     1 
ATOM   4273 C CA    . ALA C 3 35  ? 99.929  140.306 95.570  1.00 20.16  ? 35  ALA G CA    1 
ATOM   4274 C C     . ALA C 3 35  ? 100.799 139.073 95.369  1.00 20.51  ? 35  ALA G C     1 
ATOM   4275 O O     . ALA C 3 35  ? 100.553 138.028 95.979  1.00 16.17  ? 35  ALA G O     1 
ATOM   4276 C CB    . ALA C 3 35  ? 98.916  140.440 94.434  1.00 16.70  ? 35  ALA G CB    1 
ATOM   4277 N N     . ASP C 3 36  ? 101.823 139.176 94.518  1.00 20.06  ? 36  ASP G N     1 
ATOM   4278 C CA    . ASP C 3 36  ? 102.738 138.054 94.324  1.00 16.71  ? 36  ASP G CA    1 
ATOM   4279 C C     . ASP C 3 36  ? 103.489 137.729 95.609  1.00 12.71  ? 36  ASP G C     1 
ATOM   4280 O O     . ASP C 3 36  ? 103.684 136.554 95.947  1.00 24.90  ? 36  ASP G O     1 
ATOM   4281 C CB    . ASP C 3 36  ? 103.718 138.365 93.195  1.00 16.83  ? 36  ASP G CB    1 
ATOM   4282 C CG    . ASP C 3 36  ? 103.061 138.346 91.831  1.00 31.08  ? 36  ASP G CG    1 
ATOM   4283 O OD1   . ASP C 3 36  ? 101.914 137.862 91.728  1.00 30.16  ? 36  ASP G OD1   1 
ATOM   4284 O OD2   . ASP C 3 36  ? 103.692 138.813 90.861  1.00 34.42  ? 36  ASP G OD2   1 
ATOM   4285 N N     . LEU C 3 37  ? 103.921 138.761 96.336  1.00 8.69   ? 37  LEU G N     1 
ATOM   4286 C CA    . LEU C 3 37  ? 104.635 138.555 97.592  1.00 14.81  ? 37  LEU G CA    1 
ATOM   4287 C C     . LEU C 3 37  ? 103.748 137.847 98.611  1.00 5.74   ? 37  LEU G C     1 
ATOM   4288 O O     . LEU C 3 37  ? 104.168 136.881 99.266  1.00 5.17   ? 37  LEU G O     1 
ATOM   4289 C CB    . LEU C 3 37  ? 105.100 139.911 98.125  1.00 18.33  ? 37  LEU G CB    1 
ATOM   4290 C CG    . LEU C 3 37  ? 105.951 139.979 99.386  1.00 19.09  ? 37  LEU G CG    1 
ATOM   4291 C CD1   . LEU C 3 37  ? 107.262 139.281 99.124  1.00 23.44  ? 37  LEU G CD1   1 
ATOM   4292 C CD2   . LEU C 3 37  ? 106.180 141.419 99.801  1.00 12.90  ? 37  LEU G CD2   1 
ATOM   4293 N N     . MET C 3 38  ? 102.502 138.308 98.740  1.00 17.30  ? 38  MET G N     1 
ATOM   4294 C CA    . MET C 3 38  ? 101.559 137.692 99.667  1.00 11.58  ? 38  MET G CA    1 
ATOM   4295 C C     . MET C 3 38  ? 101.227 136.265 99.251  1.00 9.84   ? 38  MET G C     1 
ATOM   4296 O O     . MET C 3 38  ? 101.069 135.384 100.103 1.00 14.89  ? 38  MET G O     1 
ATOM   4297 C CB    . MET C 3 38  ? 100.291 138.541 99.751  1.00 6.71   ? 38  MET G CB    1 
ATOM   4298 C CG    . MET C 3 38  ? 99.217  137.987 100.666 1.00 22.04  ? 38  MET G CG    1 
ATOM   4299 S SD    . MET C 3 38  ? 97.795  139.088 100.781 1.00 43.67  ? 38  MET G SD    1 
ATOM   4300 C CE    . MET C 3 38  ? 97.055  138.852 99.168  1.00 22.55  ? 38  MET G CE    1 
ATOM   4301 N N     . ALA C 3 39  ? 101.107 136.019 97.944  1.00 14.20  ? 39  ALA G N     1 
ATOM   4302 C CA    . ALA C 3 39  ? 100.835 134.670 97.462  1.00 14.18  ? 39  ALA G CA    1 
ATOM   4303 C C     . ALA C 3 39  ? 101.986 133.727 97.781  1.00 14.37  ? 39  ALA G C     1 
ATOM   4304 O O     . ALA C 3 39  ? 101.763 132.584 98.192  1.00 24.86  ? 39  ALA G O     1 
ATOM   4305 C CB    . ALA C 3 39  ? 100.561 134.696 95.959  1.00 16.76  ? 39  ALA G CB    1 
ATOM   4306 N N     . TYR C 3 40  ? 103.226 134.188 97.596  1.00 8.19   ? 40  TYR G N     1 
ATOM   4307 C CA    . TYR C 3 40  ? 104.377 133.365 97.958  1.00 2.35   ? 40  TYR G CA    1 
ATOM   4308 C C     . TYR C 3 40  ? 104.387 133.070 99.452  1.00 9.51   ? 40  TYR G C     1 
ATOM   4309 O O     . TYR C 3 40  ? 104.639 131.930 99.869  1.00 16.99  ? 40  TYR G O     1 
ATOM   4310 C CB    . TYR C 3 40  ? 105.673 134.062 97.541  1.00 13.02  ? 40  TYR G CB    1 
ATOM   4311 C CG    . TYR C 3 40  ? 106.925 133.244 97.783  1.00 15.04  ? 40  TYR G CG    1 
ATOM   4312 C CD1   . TYR C 3 40  ? 107.587 133.292 99.003  1.00 12.66  ? 40  TYR G CD1   1 
ATOM   4313 C CD2   . TYR C 3 40  ? 107.448 132.430 96.788  1.00 16.90  ? 40  TYR G CD2   1 
ATOM   4314 C CE1   . TYR C 3 40  ? 108.728 132.548 99.228  1.00 8.44   ? 40  TYR G CE1   1 
ATOM   4315 C CE2   . TYR C 3 40  ? 108.591 131.685 97.003  1.00 10.64  ? 40  TYR G CE2   1 
ATOM   4316 C CZ    . TYR C 3 40  ? 109.226 131.747 98.225  1.00 10.50  ? 40  TYR G CZ    1 
ATOM   4317 O OH    . TYR C 3 40  ? 110.363 131.006 98.445  1.00 24.07  ? 40  TYR G OH    1 
ATOM   4318 N N     . CYS C 3 41  ? 104.112 134.087 100.274 1.00 17.08  ? 41  CYS G N     1 
ATOM   4319 C CA    . CYS C 3 41  ? 104.080 133.874 101.718 1.00 8.44   ? 41  CYS G CA    1 
ATOM   4320 C C     . CYS C 3 41  ? 103.002 132.868 102.103 1.00 13.68  ? 41  CYS G C     1 
ATOM   4321 O O     . CYS C 3 41  ? 103.241 131.976 102.924 1.00 22.07  ? 41  CYS G O     1 
ATOM   4322 C CB    . CYS C 3 41  ? 103.857 135.201 102.440 1.00 8.78   ? 41  CYS G CB    1 
ATOM   4323 S SG    . CYS C 3 41  ? 105.270 136.324 102.389 1.00 20.82  ? 41  CYS G SG    1 
ATOM   4324 N N     . GLU C 3 42  ? 101.811 132.989 101.514 1.00 14.54  ? 42  GLU G N     1 
ATOM   4325 C CA    . GLU C 3 42  ? 100.728 132.062 101.825 1.00 12.59  ? 42  GLU G CA    1 
ATOM   4326 C C     . GLU C 3 42  ? 101.062 130.648 101.369 1.00 15.44  ? 42  GLU G C     1 
ATOM   4327 O O     . GLU C 3 42  ? 100.748 129.675 102.066 1.00 25.57  ? 42  GLU G O     1 
ATOM   4328 C CB    . GLU C 3 42  ? 99.427  132.541 101.182 1.00 15.04  ? 42  GLU G CB    1 
ATOM   4329 N N     . ALA C 3 43  ? 101.690 130.513 100.200 1.00 13.69  ? 43  ALA G N     1 
ATOM   4330 C CA    . ALA C 3 43  ? 102.032 129.191 99.690  1.00 15.69  ? 43  ALA G CA    1 
ATOM   4331 C C     . ALA C 3 43  ? 103.083 128.511 100.557 1.00 17.95  ? 43  ALA G C     1 
ATOM   4332 O O     . ALA C 3 43  ? 103.009 127.300 100.793 1.00 26.92  ? 43  ALA G O     1 
ATOM   4333 C CB    . ALA C 3 43  ? 102.515 129.296 98.244  1.00 12.53  ? 43  ALA G CB    1 
ATOM   4334 N N     . HIS C 3 44  ? 104.070 129.265 101.039 1.00 20.11  ? 44  HIS G N     1 
ATOM   4335 C CA    . HIS C 3 44  ? 105.177 128.677 101.781 1.00 18.32  ? 44  HIS G CA    1 
ATOM   4336 C C     . HIS C 3 44  ? 105.016 128.778 103.294 1.00 18.89  ? 44  HIS G C     1 
ATOM   4337 O O     . HIS C 3 44  ? 105.928 128.382 104.027 1.00 23.08  ? 44  HIS G O     1 
ATOM   4338 C CB    . HIS C 3 44  ? 106.494 129.318 101.342 1.00 16.06  ? 44  HIS G CB    1 
ATOM   4339 C CG    . HIS C 3 44  ? 106.929 128.910 99.970  1.00 18.67  ? 44  HIS G CG    1 
ATOM   4340 N ND1   . HIS C 3 44  ? 106.357 129.422 98.825  1.00 24.35  ? 44  HIS G ND1   1 
ATOM   4341 C CD2   . HIS C 3 44  ? 107.872 128.030 99.558  1.00 20.60  ? 44  HIS G CD2   1 
ATOM   4342 C CE1   . HIS C 3 44  ? 106.932 128.879 97.767  1.00 24.26  ? 44  HIS G CE1   1 
ATOM   4343 N NE2   . HIS C 3 44  ? 107.855 128.031 98.184  1.00 27.15  ? 44  HIS G NE2   1 
ATOM   4344 N N     . ALA C 3 45  ? 103.882 129.289 103.780 1.00 16.94  ? 45  ALA G N     1 
ATOM   4345 C CA    . ALA C 3 45  ? 103.664 129.358 105.222 1.00 21.53  ? 45  ALA G CA    1 
ATOM   4346 C C     . ALA C 3 45  ? 103.648 127.974 105.858 1.00 18.36  ? 45  ALA G C     1 
ATOM   4347 O O     . ALA C 3 45  ? 104.190 127.781 106.953 1.00 18.61  ? 45  ALA G O     1 
ATOM   4348 C CB    . ALA C 3 45  ? 102.359 130.097 105.518 1.00 22.61  ? 45  ALA G CB    1 
ATOM   4349 N N     . LYS C 3 46  ? 103.026 126.998 105.192 1.00 25.01  ? 46  LYS G N     1 
ATOM   4350 C CA    . LYS C 3 46  ? 102.928 125.655 105.755 1.00 20.09  ? 46  LYS G CA    1 
ATOM   4351 C C     . LYS C 3 46  ? 104.286 124.977 105.894 1.00 21.17  ? 46  LYS G C     1 
ATOM   4352 O O     . LYS C 3 46  ? 104.401 124.000 106.642 1.00 24.98  ? 46  LYS G O     1 
ATOM   4353 C CB    . LYS C 3 46  ? 102.004 124.792 104.895 1.00 19.05  ? 46  LYS G CB    1 
ATOM   4354 N N     . GLU C 3 47  ? 105.311 125.469 105.198 1.00 26.49  ? 47  GLU G N     1 
ATOM   4355 C CA    . GLU C 3 47  ? 106.651 124.899 105.261 1.00 23.42  ? 47  GLU G CA    1 
ATOM   4356 C C     . GLU C 3 47  ? 107.631 125.805 105.999 1.00 21.55  ? 47  GLU G C     1 
ATOM   4357 O O     . GLU C 3 47  ? 108.843 125.706 105.783 1.00 21.84  ? 47  GLU G O     1 
ATOM   4358 C CB    . GLU C 3 47  ? 107.163 124.599 103.852 1.00 24.52  ? 47  GLU G CB    1 
ATOM   4359 N N     . ASP C 3 48  ? 107.133 126.685 106.866 1.00 19.08  ? 48  ASP G N     1 
ATOM   4360 C CA    . ASP C 3 48  ? 107.981 127.613 107.609 1.00 14.12  ? 48  ASP G CA    1 
ATOM   4361 C C     . ASP C 3 48  ? 108.023 127.204 109.075 1.00 19.00  ? 48  ASP G C     1 
ATOM   4362 O O     . ASP C 3 48  ? 107.059 127.451 109.816 1.00 26.87  ? 48  ASP G O     1 
ATOM   4363 C CB    . ASP C 3 48  ? 107.460 129.047 107.467 1.00 20.87  ? 48  ASP G CB    1 
ATOM   4364 C CG    . ASP C 3 48  ? 108.507 130.087 107.815 1.00 26.82  ? 48  ASP G CG    1 
ATOM   4365 O OD1   . ASP C 3 48  ? 109.607 129.704 108.264 1.00 23.88  ? 48  ASP G OD1   1 
ATOM   4366 O OD2   . ASP C 3 48  ? 108.228 131.292 107.640 1.00 22.29  ? 48  ASP G OD2   1 
ATOM   4367 N N     . PRO C 3 49  ? 109.102 126.570 109.540 1.00 18.78  ? 49  PRO G N     1 
ATOM   4368 C CA    . PRO C 3 49  ? 109.174 126.190 110.961 1.00 16.40  ? 49  PRO G CA    1 
ATOM   4369 C C     . PRO C 3 49  ? 109.127 127.372 111.912 1.00 20.81  ? 49  PRO G C     1 
ATOM   4370 O O     . PRO C 3 49  ? 108.628 127.231 113.035 1.00 27.19  ? 49  PRO G O     1 
ATOM   4371 C CB    . PRO C 3 49  ? 110.513 125.443 111.056 1.00 15.90  ? 49  PRO G CB    1 
ATOM   4372 C CG    . PRO C 3 49  ? 110.815 125.013 109.656 1.00 21.00  ? 49  PRO G CG    1 
ATOM   4373 C CD    . PRO C 3 49  ? 110.268 126.093 108.779 1.00 20.10  ? 49  PRO G CD    1 
ATOM   4374 N N     . LEU C 3 50  ? 109.649 128.531 111.507 1.00 17.12  ? 50  LEU G N     1 
ATOM   4375 C CA    . LEU C 3 50  ? 109.627 129.695 112.387 1.00 8.82   ? 50  LEU G CA    1 
ATOM   4376 C C     . LEU C 3 50  ? 108.215 130.245 112.543 1.00 15.24  ? 50  LEU G C     1 
ATOM   4377 O O     . LEU C 3 50  ? 107.823 130.660 113.640 1.00 24.80  ? 50  LEU G O     1 
ATOM   4378 C CB    . LEU C 3 50  ? 110.565 130.773 111.850 1.00 14.07  ? 50  LEU G CB    1 
ATOM   4379 C CG    . LEU C 3 50  ? 112.032 130.373 111.693 1.00 13.36  ? 50  LEU G CG    1 
ATOM   4380 C CD1   . LEU C 3 50  ? 112.811 131.490 111.024 1.00 15.59  ? 50  LEU G CD1   1 
ATOM   4381 C CD2   . LEU C 3 50  ? 112.641 130.017 113.039 1.00 11.36  ? 50  LEU G CD2   1 
ATOM   4382 N N     . LEU C 3 51  ? 107.441 130.264 111.457 1.00 22.57  ? 51  LEU G N     1 
ATOM   4383 C CA    . LEU C 3 51  ? 106.081 130.786 111.521 1.00 21.87  ? 51  LEU G CA    1 
ATOM   4384 C C     . LEU C 3 51  ? 105.192 129.903 112.388 1.00 25.43  ? 51  LEU G C     1 
ATOM   4385 O O     . LEU C 3 51  ? 104.506 130.391 113.293 1.00 33.19  ? 51  LEU G O     1 
ATOM   4386 C CB    . LEU C 3 51  ? 105.507 130.912 110.110 1.00 22.25  ? 51  LEU G CB    1 
ATOM   4387 C CG    . LEU C 3 51  ? 104.357 131.901 109.928 1.00 25.38  ? 51  LEU G CG    1 
ATOM   4388 C CD1   . LEU C 3 51  ? 104.829 133.311 110.218 1.00 22.10  ? 51  LEU G CD1   1 
ATOM   4389 C CD2   . LEU C 3 51  ? 103.786 131.802 108.524 1.00 26.90  ? 51  LEU G CD2   1 
ATOM   4390 N N     . THR C 3 52  ? 105.196 128.597 112.128 1.00 32.40  ? 52  THR G N     1 
ATOM   4391 C CA    . THR C 3 52  ? 104.422 127.640 112.905 1.00 35.67  ? 52  THR G CA    1 
ATOM   4392 C C     . THR C 3 52  ? 105.372 126.764 113.704 1.00 36.86  ? 52  THR G C     1 
ATOM   4393 O O     . THR C 3 52  ? 106.160 126.018 113.103 1.00 37.17  ? 52  THR G O     1 
ATOM   4394 C CB    . THR C 3 52  ? 103.546 126.781 111.995 1.00 41.83  ? 52  THR G CB    1 
ATOM   4395 O OG1   . THR C 3 52  ? 104.376 126.019 111.110 1.00 36.70  ? 52  THR G OG1   1 
ATOM   4396 C CG2   . THR C 3 52  ? 102.611 127.658 111.175 1.00 38.27  ? 52  THR G CG2   1 
ATOM   4397 N N     . PRO C 3 53  ? 105.340 126.818 115.036 1.00 43.96  ? 53  PRO G N     1 
ATOM   4398 C CA    . PRO C 3 53  ? 106.296 126.036 115.831 1.00 44.13  ? 53  PRO G CA    1 
ATOM   4399 C C     . PRO C 3 53  ? 106.201 124.548 115.526 1.00 43.18  ? 53  PRO G C     1 
ATOM   4400 O O     . PRO C 3 53  ? 105.113 123.998 115.338 1.00 42.90  ? 53  PRO G O     1 
ATOM   4401 C CB    . PRO C 3 53  ? 105.889 126.342 117.277 1.00 43.56  ? 53  PRO G CB    1 
ATOM   4402 C CG    . PRO C 3 53  ? 105.183 127.655 117.201 1.00 43.89  ? 53  PRO G CG    1 
ATOM   4403 C CD    . PRO C 3 53  ? 104.474 127.659 115.879 1.00 44.81  ? 53  PRO G CD    1 
ATOM   4404 N N     . VAL C 3 54  ? 107.361 123.901 115.479 1.00 47.46  ? 54  VAL G N     1 
ATOM   4405 C CA    . VAL C 3 54  ? 107.467 122.491 115.114 1.00 50.27  ? 54  VAL G CA    1 
ATOM   4406 C C     . VAL C 3 54  ? 107.496 121.650 116.385 1.00 47.13  ? 54  VAL G C     1 
ATOM   4407 O O     . VAL C 3 54  ? 108.180 122.016 117.352 1.00 47.44  ? 54  VAL G O     1 
ATOM   4408 C CB    . VAL C 3 54  ? 108.709 122.245 114.242 1.00 48.73  ? 54  VAL G CB    1 
ATOM   4409 C CG1   . VAL C 3 54  ? 108.986 120.759 114.093 1.00 46.29  ? 54  VAL G CG1   1 
ATOM   4410 C CG2   . VAL C 3 54  ? 108.529 122.890 112.878 1.00 45.39  ? 54  VAL G CG2   1 
ATOM   4411 N N     . PRO C 3 55  ? 106.767 120.534 116.437 1.00 45.17  ? 55  PRO G N     1 
ATOM   4412 C CA    . PRO C 3 55  ? 106.816 119.676 117.626 1.00 48.24  ? 55  PRO G CA    1 
ATOM   4413 C C     . PRO C 3 55  ? 108.215 119.125 117.858 1.00 48.01  ? 55  PRO G C     1 
ATOM   4414 O O     . PRO C 3 55  ? 109.019 118.995 116.932 1.00 49.03  ? 55  PRO G O     1 
ATOM   4415 C CB    . PRO C 3 55  ? 105.820 118.557 117.299 1.00 49.73  ? 55  PRO G CB    1 
ATOM   4416 C CG    . PRO C 3 55  ? 104.909 119.146 116.276 1.00 50.45  ? 55  PRO G CG    1 
ATOM   4417 C CD    . PRO C 3 55  ? 105.755 120.082 115.467 1.00 46.53  ? 55  PRO G CD    1 
ATOM   4418 N N     . ALA C 3 56  ? 108.498 118.803 119.123 1.00 47.14  ? 56  ALA G N     1 
ATOM   4419 C CA    . ALA C 3 56  ? 109.831 118.356 119.513 1.00 49.37  ? 56  ALA G CA    1 
ATOM   4420 C C     . ALA C 3 56  ? 110.269 117.094 118.781 1.00 47.05  ? 56  ALA G C     1 
ATOM   4421 O O     . ALA C 3 56  ? 111.474 116.834 118.689 1.00 46.43  ? 56  ALA G O     1 
ATOM   4422 C CB    . ALA C 3 56  ? 109.883 118.123 121.023 1.00 48.47  ? 56  ALA G CB    1 
ATOM   4423 N N     . SER C 3 57  ? 109.325 116.301 118.268 1.00 47.60  ? 57  SER G N     1 
ATOM   4424 C CA    . SER C 3 57  ? 109.695 115.107 117.515 1.00 50.60  ? 57  SER G CA    1 
ATOM   4425 C C     . SER C 3 57  ? 110.459 115.469 116.247 1.00 50.52  ? 57  SER G C     1 
ATOM   4426 O O     . SER C 3 57  ? 111.442 114.806 115.895 1.00 51.85  ? 57  SER G O     1 
ATOM   4427 C CB    . SER C 3 57  ? 108.447 114.293 117.175 1.00 52.21  ? 57  SER G CB    1 
ATOM   4428 O OG    . SER C 3 57  ? 107.579 115.021 116.324 1.00 55.77  ? 57  SER G OG    1 
ATOM   4429 N N     . GLU C 3 58  ? 110.025 116.516 115.550 1.00 42.95  ? 58  GLU G N     1 
ATOM   4430 C CA    . GLU C 3 58  ? 110.663 116.962 114.319 1.00 44.50  ? 58  GLU G CA    1 
ATOM   4431 C C     . GLU C 3 58  ? 111.566 118.171 114.530 1.00 44.93  ? 58  GLU G C     1 
ATOM   4432 O O     . GLU C 3 58  ? 111.982 118.799 113.551 1.00 45.01  ? 58  GLU G O     1 
ATOM   4433 C CB    . GLU C 3 58  ? 109.605 117.276 113.260 1.00 42.03  ? 58  GLU G CB    1 
ATOM   4434 N N     . ASN C 3 59  ? 111.876 118.513 115.780 1.00 38.77  ? 59  ASN G N     1 
ATOM   4435 C CA    . ASN C 3 59  ? 112.734 119.648 116.077 1.00 32.13  ? 59  ASN G CA    1 
ATOM   4436 C C     . ASN C 3 59  ? 114.134 119.147 116.397 1.00 32.68  ? 59  ASN G C     1 
ATOM   4437 O O     . ASN C 3 59  ? 114.328 118.513 117.445 1.00 42.08  ? 59  ASN G O     1 
ATOM   4438 C CB    . ASN C 3 59  ? 112.174 120.451 117.249 1.00 37.60  ? 59  ASN G CB    1 
ATOM   4439 C CG    . ASN C 3 59  ? 112.679 121.880 117.273 1.00 34.85  ? 59  ASN G CG    1 
ATOM   4440 O OD1   . ASN C 3 59  ? 113.768 122.175 116.784 1.00 34.63  ? 59  ASN G OD1   1 
ATOM   4441 N ND2   . ASN C 3 59  ? 111.887 122.776 117.850 1.00 35.21  ? 59  ASN G ND2   1 
ATOM   4442 N N     . PRO C 3 60  ? 115.131 119.401 115.547 1.00 27.62  ? 60  PRO G N     1 
ATOM   4443 C CA    . PRO C 3 60  ? 116.488 118.908 115.816 1.00 25.94  ? 60  PRO G CA    1 
ATOM   4444 C C     . PRO C 3 60  ? 117.247 119.701 116.866 1.00 21.52  ? 60  PRO G C     1 
ATOM   4445 O O     . PRO C 3 60  ? 118.375 119.322 117.203 1.00 21.03  ? 60  PRO G O     1 
ATOM   4446 C CB    . PRO C 3 60  ? 117.168 119.029 114.446 1.00 23.04  ? 60  PRO G CB    1 
ATOM   4447 C CG    . PRO C 3 60  ? 116.468 120.159 113.787 1.00 19.66  ? 60  PRO G CG    1 
ATOM   4448 C CD    . PRO C 3 60  ? 115.039 120.099 114.253 1.00 26.18  ? 60  PRO G CD    1 
ATOM   4449 N N     . PHE C 3 61  ? 116.674 120.784 117.391 1.00 22.92  ? 61  PHE G N     1 
ATOM   4450 C CA    . PHE C 3 61  ? 117.339 121.618 118.383 1.00 25.12  ? 61  PHE G CA    1 
ATOM   4451 C C     . PHE C 3 61  ? 116.750 121.442 119.779 1.00 30.66  ? 61  PHE G C     1 
ATOM   4452 O O     . PHE C 3 61  ? 116.953 122.297 120.646 1.00 29.28  ? 61  PHE G O     1 
ATOM   4453 C CB    . PHE C 3 61  ? 117.286 123.086 117.960 1.00 24.68  ? 61  PHE G CB    1 
ATOM   4454 C CG    . PHE C 3 61  ? 118.142 123.399 116.767 1.00 20.20  ? 61  PHE G CG    1 
ATOM   4455 C CD1   . PHE C 3 61  ? 119.495 123.651 116.917 1.00 17.16  ? 61  PHE G CD1   1 
ATOM   4456 C CD2   . PHE C 3 61  ? 117.596 123.432 115.496 1.00 19.53  ? 61  PHE G CD2   1 
ATOM   4457 C CE1   . PHE C 3 61  ? 120.285 123.935 115.823 1.00 16.94  ? 61  PHE G CE1   1 
ATOM   4458 C CE2   . PHE C 3 61  ? 118.382 123.716 114.397 1.00 20.80  ? 61  PHE G CE2   1 
ATOM   4459 C CZ    . PHE C 3 61  ? 119.729 123.968 114.562 1.00 21.71  ? 61  PHE G CZ    1 
ATOM   4460 N N     . ARG C 3 62  ? 116.029 120.351 120.013 1.00 42.55  ? 62  ARG G N     1 
ATOM   4461 C CA    . ARG C 3 62  ? 115.449 120.087 121.323 1.00 40.13  ? 62  ARG G CA    1 
ATOM   4462 C C     . ARG C 3 62  ? 116.440 119.359 122.225 1.00 44.59  ? 62  ARG G C     1 
ATOM   4463 O O     . ARG C 3 62  ? 117.587 119.127 121.844 1.00 46.35  ? 62  ARG G O     1 
ATOM   4464 C CB    . ARG C 3 62  ? 114.165 119.269 121.185 1.00 38.42  ? 62  ARG G CB    1 
ATOM   4465 C CG    . ARG C 3 62  ? 112.954 120.089 120.781 1.00 41.34  ? 62  ARG G CG    1 
ATOM   4466 C CD    . ARG C 3 62  ? 112.702 121.223 121.759 1.00 42.76  ? 62  ARG G CD    1 
ATOM   4467 N NE    . ARG C 3 62  ? 111.441 121.903 121.489 1.00 48.96  ? 62  ARG G NE    1 
ATOM   4468 C CZ    . ARG C 3 62  ? 110.453 122.026 122.365 1.00 46.02  ? 62  ARG G CZ    1 
ATOM   4469 N NH1   . ARG C 3 62  ? 110.546 121.526 123.586 1.00 42.59  ? 62  ARG G NH1   1 
ATOM   4470 N NH2   . ARG C 3 62  ? 109.344 122.667 122.006 1.00 42.27  ? 62  ARG G NH2   1 
ATOM   4471 N N     . SER D 4 178 ? 121.377 137.597 187.012 1.00 100.06 ? 15  SER R N     1 
ATOM   4472 C CA    . SER D 4 178 ? 120.646 136.670 186.157 1.00 100.77 ? 15  SER R CA    1 
ATOM   4473 C C     . SER D 4 178 ? 120.402 137.273 184.777 1.00 101.96 ? 15  SER R C     1 
ATOM   4474 O O     . SER D 4 178 ? 121.240 137.160 183.883 1.00 100.07 ? 15  SER R O     1 
ATOM   4475 C CB    . SER D 4 178 ? 119.316 136.279 186.804 1.00 100.61 ? 15  SER R CB    1 
ATOM   4476 O OG    . SER D 4 178 ? 118.540 137.425 187.108 1.00 101.00 ? 15  SER R OG    1 
ATOM   4477 N N     . GLN D 4 179 ? 119.244 137.910 184.609 1.00 103.77 ? 16  GLN R N     1 
ATOM   4478 C CA    . GLN D 4 179 ? 118.880 138.549 183.354 1.00 101.39 ? 16  GLN R CA    1 
ATOM   4479 C C     . GLN D 4 179 ? 118.141 139.846 183.646 1.00 102.70 ? 16  GLN R C     1 
ATOM   4480 O O     . GLN D 4 179 ? 117.518 140.000 184.699 1.00 103.87 ? 16  GLN R O     1 
ATOM   4481 C CB    . GLN D 4 179 ? 118.006 137.637 182.480 1.00 101.61 ? 16  GLN R CB    1 
ATOM   4482 C CG    . GLN D 4 179 ? 118.726 136.418 181.920 1.00 103.84 ? 16  GLN R CG    1 
ATOM   4483 C CD    . GLN D 4 179 ? 119.722 136.773 180.832 1.00 105.72 ? 16  GLN R CD    1 
ATOM   4484 O OE1   . GLN D 4 179 ? 119.706 137.880 180.294 1.00 106.89 ? 16  GLN R OE1   1 
ATOM   4485 N NE2   . GLN D 4 179 ? 120.598 135.830 180.502 1.00 102.91 ? 16  GLN R NE2   1 
ATOM   4486 N N     . ASN D 4 180 ? 118.218 140.782 182.697 1.00 105.76 ? 17  ASN R N     1 
ATOM   4487 C CA    . ASN D 4 180 ? 117.519 142.054 182.810 1.00 106.71 ? 17  ASN R CA    1 
ATOM   4488 C C     . ASN D 4 180 ? 116.286 142.155 181.926 1.00 107.63 ? 17  ASN R C     1 
ATOM   4489 O O     . ASN D 4 180 ? 115.471 143.059 182.138 1.00 105.41 ? 17  ASN R O     1 
ATOM   4490 C CB    . ASN D 4 180 ? 118.465 143.220 182.479 1.00 104.78 ? 17  ASN R CB    1 
ATOM   4491 C CG    . ASN D 4 180 ? 119.229 143.008 181.184 1.00 104.92 ? 17  ASN R CG    1 
ATOM   4492 O OD1   . ASN D 4 180 ? 118.732 142.381 180.248 1.00 103.62 ? 17  ASN R OD1   1 
ATOM   4493 N ND2   . ASN D 4 180 ? 120.445 143.536 181.125 1.00 103.58 ? 17  ASN R ND2   1 
ATOM   4494 N N     . LEU D 4 181 ? 116.139 141.269 180.941 1.00 106.98 ? 18  LEU R N     1 
ATOM   4495 C CA    . LEU D 4 181 ? 115.018 141.198 180.006 1.00 105.93 ? 18  LEU R CA    1 
ATOM   4496 C C     . LEU D 4 181 ? 114.918 142.422 179.105 1.00 106.57 ? 18  LEU R C     1 
ATOM   4497 O O     . LEU D 4 181 ? 113.956 142.528 178.335 1.00 108.22 ? 18  LEU R O     1 
ATOM   4498 C CB    . LEU D 4 181 ? 113.669 140.997 180.717 1.00 105.86 ? 18  LEU R CB    1 
ATOM   4499 C CG    . LEU D 4 181 ? 113.259 139.575 181.115 1.00 105.26 ? 18  LEU R CG    1 
ATOM   4500 C CD1   . LEU D 4 181 ? 113.083 138.701 179.883 1.00 105.88 ? 18  LEU R CD1   1 
ATOM   4501 C CD2   . LEU D 4 181 ? 114.246 138.945 182.090 1.00 104.33 ? 18  LEU R CD2   1 
ATOM   4502 N N     . LEU D 4 182 ? 115.872 143.350 179.171 1.00 103.59 ? 19  LEU R N     1 
ATOM   4503 C CA    . LEU D 4 182 ? 115.844 144.545 178.336 1.00 103.18 ? 19  LEU R CA    1 
ATOM   4504 C C     . LEU D 4 182 ? 116.711 144.398 177.092 1.00 103.21 ? 19  LEU R C     1 
ATOM   4505 O O     . LEU D 4 182 ? 116.377 144.946 176.036 1.00 101.83 ? 19  LEU R O     1 
ATOM   4506 C CB    . LEU D 4 182 ? 116.298 145.761 179.150 1.00 102.13 ? 19  LEU R CB    1 
ATOM   4507 C CG    . LEU D 4 182 ? 116.441 147.095 178.413 1.00 101.88 ? 19  LEU R CG    1 
ATOM   4508 C CD1   . LEU D 4 182 ? 115.127 147.495 177.761 1.00 100.99 ? 19  LEU R CD1   1 
ATOM   4509 C CD2   . LEU D 4 182 ? 116.927 148.182 179.359 1.00 102.33 ? 19  LEU R CD2   1 
ATOM   4510 N N     . ILE D 4 183 ? 117.816 143.663 177.193 1.00 99.74  ? 20  ILE R N     1 
ATOM   4511 C CA    . ILE D 4 183 ? 118.745 143.513 176.079 1.00 95.58  ? 20  ILE R CA    1 
ATOM   4512 C C     . ILE D 4 183 ? 118.355 142.306 175.237 1.00 97.36  ? 20  ILE R C     1 
ATOM   4513 O O     . ILE D 4 183 ? 118.054 142.438 174.046 1.00 97.45  ? 20  ILE R O     1 
ATOM   4514 C CB    . ILE D 4 183 ? 120.195 143.386 176.580 1.00 94.91  ? 20  ILE R CB    1 
ATOM   4515 C CG1   . ILE D 4 183 ? 120.635 144.679 177.270 1.00 95.76  ? 20  ILE R CG1   1 
ATOM   4516 C CG2   . ILE D 4 183 ? 121.129 143.047 175.430 1.00 96.08  ? 20  ILE R CG2   1 
ATOM   4517 C CD1   . ILE D 4 183 ? 121.979 144.578 177.955 1.00 96.14  ? 20  ILE R CD1   1 
ATOM   4518 N N     . THR D 4 184 ? 118.347 141.123 175.854 1.00 103.82 ? 21  THR R N     1 
ATOM   4519 C CA    . THR D 4 184 ? 118.147 139.879 175.119 1.00 104.93 ? 21  THR R CA    1 
ATOM   4520 C C     . THR D 4 184 ? 116.734 139.716 174.573 1.00 104.38 ? 21  THR R C     1 
ATOM   4521 O O     . THR D 4 184 ? 116.527 138.865 173.702 1.00 103.59 ? 21  THR R O     1 
ATOM   4522 C CB    . THR D 4 184 ? 118.484 138.681 176.008 1.00 102.93 ? 21  THR R CB    1 
ATOM   4523 O OG1   . THR D 4 184 ? 117.900 138.865 177.304 1.00 101.84 ? 21  THR R OG1   1 
ATOM   4524 C CG2   . THR D 4 184 ? 119.990 138.533 176.151 1.00 101.74 ? 21  THR R CG2   1 
ATOM   4525 N N     . GLN D 4 185 ? 115.764 140.496 175.052 1.00 105.41 ? 22  GLN R N     1 
ATOM   4526 C CA    . GLN D 4 185 ? 114.384 140.334 174.619 1.00 103.92 ? 22  GLN R CA    1 
ATOM   4527 C C     . GLN D 4 185 ? 113.761 141.580 174.006 1.00 104.42 ? 22  GLN R C     1 
ATOM   4528 O O     . GLN D 4 185 ? 112.712 141.461 173.363 1.00 104.32 ? 22  GLN R O     1 
ATOM   4529 C CB    . GLN D 4 185 ? 113.502 139.870 175.789 1.00 102.80 ? 22  GLN R CB    1 
ATOM   4530 C CG    . GLN D 4 185 ? 113.738 138.428 176.204 1.00 103.21 ? 22  GLN R CG    1 
ATOM   4531 C CD    . GLN D 4 185 ? 112.458 137.720 176.603 1.00 105.85 ? 22  GLN R CD    1 
ATOM   4532 O OE1   . GLN D 4 185 ? 111.394 138.334 176.680 1.00 107.94 ? 22  GLN R OE1   1 
ATOM   4533 N NE2   . GLN D 4 185 ? 112.556 136.421 176.859 1.00 104.85 ? 22  GLN R NE2   1 
ATOM   4534 N N     . GLN D 4 186 ? 114.353 142.760 174.178 1.00 104.95 ? 23  GLN R N     1 
ATOM   4535 C CA    . GLN D 4 186 ? 113.796 143.979 173.604 1.00 107.27 ? 23  GLN R CA    1 
ATOM   4536 C C     . GLN D 4 186 ? 114.721 144.634 172.591 1.00 106.42 ? 23  GLN R C     1 
ATOM   4537 O O     . GLN D 4 186 ? 114.307 144.878 171.452 1.00 102.35 ? 23  GLN R O     1 
ATOM   4538 C CB    . GLN D 4 186 ? 113.447 144.975 174.720 1.00 105.42 ? 23  GLN R CB    1 
ATOM   4539 C CG    . GLN D 4 186 ? 112.437 144.444 175.726 1.00 105.68 ? 23  GLN R CG    1 
ATOM   4540 C CD    . GLN D 4 186 ? 111.887 145.529 176.631 1.00 108.75 ? 23  GLN R CD    1 
ATOM   4541 O OE1   . GLN D 4 186 ? 112.198 146.708 176.467 1.00 107.20 ? 23  GLN R OE1   1 
ATOM   4542 N NE2   . GLN D 4 186 ? 111.062 145.134 177.594 1.00 106.90 ? 23  GLN R NE2   1 
ATOM   4543 N N     . ILE D 4 187 ? 115.968 144.922 172.966 1.00 99.42  ? 24  ILE R N     1 
ATOM   4544 C CA    . ILE D 4 187 ? 116.871 145.628 172.062 1.00 95.51  ? 24  ILE R CA    1 
ATOM   4545 C C     . ILE D 4 187 ? 117.434 144.686 171.004 1.00 94.82  ? 24  ILE R C     1 
ATOM   4546 O O     . ILE D 4 187 ? 117.481 145.026 169.816 1.00 96.83  ? 24  ILE R O     1 
ATOM   4547 C CB    . ILE D 4 187 ? 117.992 146.314 172.862 1.00 93.48  ? 24  ILE R CB    1 
ATOM   4548 N N     . ILE D 4 188 ? 117.883 143.499 171.418 1.00 92.79  ? 25  ILE R N     1 
ATOM   4549 C CA    . ILE D 4 188 ? 118.441 142.544 170.459 1.00 93.85  ? 25  ILE R CA    1 
ATOM   4550 C C     . ILE D 4 188 ? 117.422 142.131 169.403 1.00 92.52  ? 25  ILE R C     1 
ATOM   4551 O O     . ILE D 4 188 ? 117.757 142.169 168.207 1.00 93.11  ? 25  ILE R O     1 
ATOM   4552 C CB    . ILE D 4 188 ? 119.047 141.341 171.206 1.00 96.17  ? 25  ILE R CB    1 
ATOM   4553 C CG1   . ILE D 4 188 ? 120.376 141.726 171.859 1.00 95.99  ? 25  ILE R CG1   1 
ATOM   4554 C CG2   . ILE D 4 188 ? 119.233 140.161 170.268 1.00 95.66  ? 25  ILE R CG2   1 
ATOM   4555 C CD1   . ILE D 4 188 ? 121.477 142.028 170.874 1.00 92.32  ? 25  ILE R CD1   1 
ATOM   4556 N N     . PRO D 4 189 ? 116.191 141.722 169.750 1.00 97.47  ? 26  PRO R N     1 
ATOM   4557 C CA    . PRO D 4 189 ? 115.236 141.359 168.688 1.00 97.32  ? 26  PRO R CA    1 
ATOM   4558 C C     . PRO D 4 189 ? 114.898 142.503 167.749 1.00 96.89  ? 26  PRO R C     1 
ATOM   4559 O O     . PRO D 4 189 ? 114.784 142.281 166.538 1.00 94.34  ? 26  PRO R O     1 
ATOM   4560 C CB    . PRO D 4 189 ? 114.004 140.885 169.473 1.00 99.70  ? 26  PRO R CB    1 
ATOM   4561 C CG    . PRO D 4 189 ? 114.530 140.489 170.801 1.00 98.17  ? 26  PRO R CG    1 
ATOM   4562 C CD    . PRO D 4 189 ? 115.622 141.468 171.086 1.00 98.53  ? 26  PRO R CD    1 
ATOM   4563 N N     . VAL D 4 190 ? 114.745 143.727 168.262 1.00 97.01  ? 27  VAL R N     1 
ATOM   4564 C CA    . VAL D 4 190 ? 114.370 144.834 167.387 1.00 96.82  ? 27  VAL R CA    1 
ATOM   4565 C C     . VAL D 4 190 ? 115.529 145.207 166.468 1.00 96.65  ? 27  VAL R C     1 
ATOM   4566 O O     . VAL D 4 190 ? 115.325 145.509 165.287 1.00 97.09  ? 27  VAL R O     1 
ATOM   4567 C CB    . VAL D 4 190 ? 113.859 146.038 168.206 1.00 97.52  ? 27  VAL R CB    1 
ATOM   4568 C CG1   . VAL D 4 190 ? 114.984 146.737 168.956 1.00 96.29  ? 27  VAL R CG1   1 
ATOM   4569 C CG2   . VAL D 4 190 ? 113.128 147.020 167.302 1.00 96.17  ? 27  VAL R CG2   1 
ATOM   4570 N N     . LEU D 4 191 ? 116.763 145.175 166.981 1.00 93.05  ? 28  LEU R N     1 
ATOM   4571 C CA    . LEU D 4 191 ? 117.912 145.457 166.127 1.00 87.06  ? 28  LEU R CA    1 
ATOM   4572 C C     . LEU D 4 191 ? 118.095 144.371 165.073 1.00 87.39  ? 28  LEU R C     1 
ATOM   4573 O O     . LEU D 4 191 ? 118.431 144.665 163.918 1.00 90.57  ? 28  LEU R O     1 
ATOM   4574 C CB    . LEU D 4 191 ? 119.173 145.608 166.975 1.00 82.24  ? 28  LEU R CB    1 
ATOM   4575 C CG    . LEU D 4 191 ? 119.336 146.920 167.742 1.00 86.81  ? 28  LEU R CG    1 
ATOM   4576 C CD1   . LEU D 4 191 ? 120.530 146.845 168.680 1.00 87.99  ? 28  LEU R CD1   1 
ATOM   4577 C CD2   . LEU D 4 191 ? 119.480 148.087 166.780 1.00 88.87  ? 28  LEU R CD2   1 
ATOM   4578 N N     . TYR D 4 192 ? 117.874 143.107 165.449 1.00 85.65  ? 29  TYR R N     1 
ATOM   4579 C CA    . TYR D 4 192 ? 117.955 142.028 164.472 1.00 84.91  ? 29  TYR R CA    1 
ATOM   4580 C C     . TYR D 4 192 ? 116.867 142.154 163.413 1.00 86.66  ? 29  TYR R C     1 
ATOM   4581 O O     . TYR D 4 192 ? 117.114 141.888 162.235 1.00 86.56  ? 29  TYR R O     1 
ATOM   4582 C CB    . TYR D 4 192 ? 117.880 140.673 165.172 1.00 84.17  ? 29  TYR R CB    1 
ATOM   4583 C CG    . TYR D 4 192 ? 119.232 140.088 165.518 1.00 85.37  ? 29  TYR R CG    1 
ATOM   4584 C CD1   . TYR D 4 192 ? 119.995 139.441 164.555 1.00 84.40  ? 29  TYR R CD1   1 
ATOM   4585 C CD2   . TYR D 4 192 ? 119.745 140.183 166.803 1.00 84.84  ? 29  TYR R CD2   1 
ATOM   4586 C CE1   . TYR D 4 192 ? 121.230 138.904 164.863 1.00 82.15  ? 29  TYR R CE1   1 
ATOM   4587 C CE2   . TYR D 4 192 ? 120.979 139.649 167.121 1.00 84.65  ? 29  TYR R CE2   1 
ATOM   4588 C CZ    . TYR D 4 192 ? 121.717 139.011 166.148 1.00 81.08  ? 29  TYR R CZ    1 
ATOM   4589 O OH    . TYR D 4 192 ? 122.946 138.479 166.462 1.00 81.12  ? 29  TYR R OH    1 
ATOM   4590 N N     . CYS D 4 193 ? 115.656 142.556 163.807 1.00 95.28  ? 30  CYS R N     1 
ATOM   4591 C CA    . CYS D 4 193 ? 114.610 142.804 162.819 1.00 97.27  ? 30  CYS R CA    1 
ATOM   4592 C C     . CYS D 4 193 ? 114.995 143.944 161.885 1.00 96.05  ? 30  CYS R C     1 
ATOM   4593 O O     . CYS D 4 193 ? 114.780 143.863 160.668 1.00 94.79  ? 30  CYS R O     1 
ATOM   4594 C CB    . CYS D 4 193 ? 113.286 143.114 163.517 1.00 96.25  ? 30  CYS R CB    1 
ATOM   4595 S SG    . CYS D 4 193 ? 112.342 141.665 164.030 1.00 103.77 ? 30  CYS R SG    1 
ATOM   4596 N N     . MET D 4 194 ? 115.560 145.019 162.440 1.00 95.49  ? 31  MET R N     1 
ATOM   4597 C CA    . MET D 4 194 ? 115.948 146.164 161.623 1.00 93.76  ? 31  MET R CA    1 
ATOM   4598 C C     . MET D 4 194 ? 117.025 145.785 160.616 1.00 92.37  ? 31  MET R C     1 
ATOM   4599 O O     . MET D 4 194 ? 116.997 146.238 159.466 1.00 93.32  ? 31  MET R O     1 
ATOM   4600 C CB    . MET D 4 194 ? 116.428 147.308 162.517 1.00 91.62  ? 31  MET R CB    1 
ATOM   4601 N N     . VAL D 4 195 ? 117.997 144.970 161.032 1.00 87.34  ? 32  VAL R N     1 
ATOM   4602 C CA    . VAL D 4 195 ? 119.020 144.547 160.082 1.00 87.49  ? 32  VAL R CA    1 
ATOM   4603 C C     . VAL D 4 195 ? 118.457 143.532 159.089 1.00 86.26  ? 32  VAL R C     1 
ATOM   4604 O O     . VAL D 4 195 ? 118.841 143.531 157.914 1.00 87.97  ? 32  VAL R O     1 
ATOM   4605 C CB    . VAL D 4 195 ? 120.269 144.012 160.813 1.00 85.61  ? 32  VAL R CB    1 
ATOM   4606 C CG1   . VAL D 4 195 ? 120.000 142.678 161.483 1.00 83.16  ? 32  VAL R CG1   1 
ATOM   4607 C CG2   . VAL D 4 195 ? 121.425 143.890 159.844 1.00 85.91  ? 32  VAL R CG2   1 
ATOM   4608 N N     . PHE D 4 196 ? 117.532 142.672 159.526 1.00 89.23  ? 33  PHE R N     1 
ATOM   4609 C CA    . PHE D 4 196 ? 117.010 141.621 158.659 1.00 91.61  ? 33  PHE R CA    1 
ATOM   4610 C C     . PHE D 4 196 ? 116.142 142.188 157.544 1.00 92.25  ? 33  PHE R C     1 
ATOM   4611 O O     . PHE D 4 196 ? 116.240 141.746 156.393 1.00 91.78  ? 33  PHE R O     1 
ATOM   4612 C CB    . PHE D 4 196 ? 116.220 140.610 159.491 1.00 91.79  ? 33  PHE R CB    1 
ATOM   4613 C CG    . PHE D 4 196 ? 115.242 139.796 158.694 1.00 92.00  ? 33  PHE R CG    1 
ATOM   4614 C CD1   . PHE D 4 196 ? 115.681 138.807 157.831 1.00 90.28  ? 33  PHE R CD1   1 
ATOM   4615 C CD2   . PHE D 4 196 ? 113.880 140.020 158.812 1.00 92.66  ? 33  PHE R CD2   1 
ATOM   4616 C CE1   . PHE D 4 196 ? 114.779 138.058 157.099 1.00 92.83  ? 33  PHE R CE1   1 
ATOM   4617 C CE2   . PHE D 4 196 ? 112.975 139.274 158.083 1.00 93.12  ? 33  PHE R CE2   1 
ATOM   4618 C CZ    . PHE D 4 196 ? 113.425 138.292 157.225 1.00 93.52  ? 33  PHE R CZ    1 
ATOM   4619 N N     . ILE D 4 197 ? 115.286 143.165 157.863 1.00 93.09  ? 34  ILE R N     1 
ATOM   4620 C CA    . ILE D 4 197 ? 114.359 143.695 156.866 1.00 92.03  ? 34  ILE R CA    1 
ATOM   4621 C C     . ILE D 4 197 ? 115.094 144.307 155.682 1.00 91.50  ? 34  ILE R C     1 
ATOM   4622 O O     . ILE D 4 197 ? 114.530 144.402 154.587 1.00 93.49  ? 34  ILE R O     1 
ATOM   4623 C CB    . ILE D 4 197 ? 113.397 144.722 157.500 1.00 92.61  ? 34  ILE R CB    1 
ATOM   4624 C CG1   . ILE D 4 197 ? 114.177 145.851 158.173 1.00 91.67  ? 34  ILE R CG1   1 
ATOM   4625 C CG2   . ILE D 4 197 ? 112.457 144.039 158.484 1.00 91.75  ? 34  ILE R CG2   1 
ATOM   4626 C CD1   . ILE D 4 197 ? 113.315 147.014 158.613 1.00 92.27  ? 34  ILE R CD1   1 
ATOM   4627 N N     . ALA D 4 198 ? 116.343 144.725 155.873 1.00 86.20  ? 35  ALA R N     1 
ATOM   4628 C CA    . ALA D 4 198 ? 117.182 145.203 154.783 1.00 84.06  ? 35  ALA R CA    1 
ATOM   4629 C C     . ALA D 4 198 ? 118.070 144.113 154.201 1.00 84.58  ? 35  ALA R C     1 
ATOM   4630 O O     . ALA D 4 198 ? 118.266 144.067 152.981 1.00 89.05  ? 35  ALA R O     1 
ATOM   4631 C CB    . ALA D 4 198 ? 118.055 146.369 155.258 1.00 83.66  ? 35  ALA R CB    1 
ATOM   4632 N N     . GLY D 4 199 ? 118.606 143.230 155.048 1.00 79.95  ? 36  GLY R N     1 
ATOM   4633 C CA    . GLY D 4 199 ? 119.510 142.204 154.561 1.00 80.25  ? 36  GLY R CA    1 
ATOM   4634 C C     . GLY D 4 199 ? 118.833 141.201 153.650 1.00 82.88  ? 36  GLY R C     1 
ATOM   4635 O O     . GLY D 4 199 ? 119.399 140.803 152.629 1.00 83.47  ? 36  GLY R O     1 
ATOM   4636 N N     . ILE D 4 200 ? 117.616 140.776 154.001 1.00 83.61  ? 37  ILE R N     1 
ATOM   4637 C CA    . ILE D 4 200 ? 116.918 139.806 153.162 1.00 83.86  ? 37  ILE R CA    1 
ATOM   4638 C C     . ILE D 4 200 ? 116.628 140.402 151.789 1.00 84.84  ? 37  ILE R C     1 
ATOM   4639 O O     . ILE D 4 200 ? 116.820 139.744 150.761 1.00 84.08  ? 37  ILE R O     1 
ATOM   4640 C CB    . ILE D 4 200 ? 115.640 139.295 153.858 1.00 83.02  ? 37  ILE R CB    1 
ATOM   4641 C CG1   . ILE D 4 200 ? 115.020 138.150 153.055 1.00 83.81  ? 37  ILE R CG1   1 
ATOM   4642 C CG2   . ILE D 4 200 ? 114.623 140.410 154.075 1.00 85.90  ? 37  ILE R CG2   1 
ATOM   4643 C CD1   . ILE D 4 200 ? 115.908 136.931 152.947 1.00 80.94  ? 37  ILE R CD1   1 
ATOM   4644 N N     . LEU D 4 201 ? 116.194 141.664 151.747 1.00 84.73  ? 38  LEU R N     1 
ATOM   4645 C CA    . LEU D 4 201 ? 115.898 142.308 150.471 1.00 84.89  ? 38  LEU R CA    1 
ATOM   4646 C C     . LEU D 4 201 ? 117.161 142.491 149.637 1.00 84.19  ? 38  LEU R C     1 
ATOM   4647 O O     . LEU D 4 201 ? 117.166 142.219 148.428 1.00 83.83  ? 38  LEU R O     1 
ATOM   4648 C CB    . LEU D 4 201 ? 115.210 143.651 150.714 1.00 84.58  ? 38  LEU R CB    1 
ATOM   4649 C CG    . LEU D 4 201 ? 114.777 144.440 149.477 1.00 87.84  ? 38  LEU R CG    1 
ATOM   4650 C CD1   . LEU D 4 201 ? 113.754 143.656 148.671 1.00 84.89  ? 38  LEU R CD1   1 
ATOM   4651 C CD2   . LEU D 4 201 ? 114.223 145.798 149.879 1.00 85.85  ? 38  LEU R CD2   1 
ATOM   4652 N N     . LEU D 4 202 ? 118.246 142.954 150.268 1.00 77.52  ? 39  LEU R N     1 
ATOM   4653 C CA    . LEU D 4 202 ? 119.491 143.156 149.536 1.00 76.60  ? 39  LEU R CA    1 
ATOM   4654 C C     . LEU D 4 202 ? 120.031 141.841 148.993 1.00 78.21  ? 39  LEU R C     1 
ATOM   4655 O O     . LEU D 4 202 ? 120.461 141.768 147.836 1.00 80.03  ? 39  LEU R O     1 
ATOM   4656 C CB    . LEU D 4 202 ? 120.526 143.833 150.434 1.00 74.41  ? 39  LEU R CB    1 
ATOM   4657 C CG    . LEU D 4 202 ? 120.311 145.324 150.702 1.00 75.20  ? 39  LEU R CG    1 
ATOM   4658 C CD1   . LEU D 4 202 ? 121.268 145.820 151.774 1.00 76.65  ? 39  LEU R CD1   1 
ATOM   4659 C CD2   . LEU D 4 202 ? 120.472 146.126 149.421 1.00 76.56  ? 39  LEU R CD2   1 
ATOM   4660 N N     . ASN D 4 203 ? 120.001 140.783 149.805 1.00 81.13  ? 40  ASN R N     1 
ATOM   4661 C CA    . ASN D 4 203 ? 120.488 139.489 149.345 1.00 82.93  ? 40  ASN R CA    1 
ATOM   4662 C C     . ASN D 4 203 ? 119.598 138.923 148.247 1.00 84.81  ? 40  ASN R C     1 
ATOM   4663 O O     . ASN D 4 203 ? 120.096 138.318 147.292 1.00 83.05  ? 40  ASN R O     1 
ATOM   4664 C CB    . ASN D 4 203 ? 120.584 138.520 150.520 1.00 80.49  ? 40  ASN R CB    1 
ATOM   4665 C CG    . ASN D 4 203 ? 121.608 138.957 151.545 1.00 81.30  ? 40  ASN R CG    1 
ATOM   4666 O OD1   . ASN D 4 203 ? 121.481 138.659 152.731 1.00 84.92  ? 40  ASN R OD1   1 
ATOM   4667 N ND2   . ASN D 4 203 ? 122.627 139.677 151.092 1.00 76.20  ? 40  ASN R ND2   1 
ATOM   4668 N N     . GLY D 4 204 ? 118.282 139.115 148.356 1.00 86.99  ? 41  GLY R N     1 
ATOM   4669 C CA    . GLY D 4 204 ? 117.391 138.636 147.314 1.00 85.72  ? 41  GLY R CA    1 
ATOM   4670 C C     . GLY D 4 204 ? 117.635 139.321 145.984 1.00 83.54  ? 41  GLY R C     1 
ATOM   4671 O O     . GLY D 4 204 ? 117.723 138.667 144.942 1.00 86.58  ? 41  GLY R O     1 
ATOM   4672 N N     . VAL D 4 205 ? 117.763 140.650 146.002 1.00 75.07  ? 42  VAL R N     1 
ATOM   4673 C CA    . VAL D 4 205 ? 117.992 141.368 144.750 1.00 78.53  ? 42  VAL R CA    1 
ATOM   4674 C C     . VAL D 4 205 ? 119.377 141.046 144.194 1.00 80.19  ? 42  VAL R C     1 
ATOM   4675 O O     . VAL D 4 205 ? 119.555 140.920 142.976 1.00 76.17  ? 42  VAL R O     1 
ATOM   4676 C CB    . VAL D 4 205 ? 117.770 142.883 144.936 1.00 76.30  ? 42  VAL R CB    1 
ATOM   4677 C CG1   . VAL D 4 205 ? 118.818 143.499 145.846 1.00 76.65  ? 42  VAL R CG1   1 
ATOM   4678 C CG2   . VAL D 4 205 ? 117.749 143.586 143.586 1.00 79.02  ? 42  VAL R CG2   1 
ATOM   4679 N N     . SER D 4 206 ? 120.373 140.880 145.072 1.00 83.05  ? 43  SER R N     1 
ATOM   4680 C CA    . SER D 4 206 ? 121.710 140.518 144.611 1.00 78.62  ? 43  SER R CA    1 
ATOM   4681 C C     . SER D 4 206 ? 121.722 139.135 143.974 1.00 79.59  ? 43  SER R C     1 
ATOM   4682 O O     . SER D 4 206 ? 122.367 138.927 142.942 1.00 84.10  ? 43  SER R O     1 
ATOM   4683 C CB    . SER D 4 206 ? 122.699 140.585 145.774 1.00 80.68  ? 43  SER R CB    1 
ATOM   4684 O OG    . SER D 4 206 ? 122.662 141.855 146.400 1.00 78.69  ? 43  SER R OG    1 
ATOM   4685 N N     . GLY D 4 207 ? 121.022 138.172 144.578 1.00 80.00  ? 44  GLY R N     1 
ATOM   4686 C CA    . GLY D 4 207 ? 120.941 136.848 143.986 1.00 80.21  ? 44  GLY R CA    1 
ATOM   4687 C C     . GLY D 4 207 ? 120.168 136.839 142.682 1.00 81.97  ? 44  GLY R C     1 
ATOM   4688 O O     . GLY D 4 207 ? 120.512 136.105 141.751 1.00 79.77  ? 44  GLY R O     1 
ATOM   4689 N N     . TRP D 4 208 ? 119.108 137.647 142.600 1.00 87.67  ? 45  TRP R N     1 
ATOM   4690 C CA    . TRP D 4 208 ? 118.356 137.755 141.355 1.00 90.07  ? 45  TRP R CA    1 
ATOM   4691 C C     . TRP D 4 208 ? 119.221 138.329 140.240 1.00 89.95  ? 45  TRP R C     1 
ATOM   4692 O O     . TRP D 4 208 ? 119.171 137.856 139.098 1.00 90.00  ? 45  TRP R O     1 
ATOM   4693 C CB    . TRP D 4 208 ? 117.110 138.615 141.576 1.00 87.61  ? 45  TRP R CB    1 
ATOM   4694 C CG    . TRP D 4 208 ? 116.518 139.181 140.322 1.00 88.72  ? 45  TRP R CG    1 
ATOM   4695 C CD1   . TRP D 4 208 ? 116.660 140.453 139.850 1.00 86.41  ? 45  TRP R CD1   1 
ATOM   4696 C CD2   . TRP D 4 208 ? 115.679 138.497 139.384 1.00 90.09  ? 45  TRP R CD2   1 
ATOM   4697 N NE1   . TRP D 4 208 ? 115.966 140.603 138.675 1.00 87.59  ? 45  TRP R NE1   1 
ATOM   4698 C CE2   . TRP D 4 208 ? 115.355 139.416 138.366 1.00 90.12  ? 45  TRP R CE2   1 
ATOM   4699 C CE3   . TRP D 4 208 ? 115.173 137.196 139.304 1.00 89.66  ? 45  TRP R CE3   1 
ATOM   4700 C CZ2   . TRP D 4 208 ? 114.548 139.076 137.282 1.00 90.19  ? 45  TRP R CZ2   1 
ATOM   4701 C CZ3   . TRP D 4 208 ? 114.371 136.860 138.227 1.00 90.05  ? 45  TRP R CZ3   1 
ATOM   4702 C CH2   . TRP D 4 208 ? 114.067 137.797 137.231 1.00 90.91  ? 45  TRP R CH2   1 
ATOM   4703 N N     . ILE D 4 209 ? 120.021 139.350 140.552 1.00 79.99  ? 46  ILE R N     1 
ATOM   4704 C CA    . ILE D 4 209 ? 120.878 139.959 139.539 1.00 77.60  ? 46  ILE R CA    1 
ATOM   4705 C C     . ILE D 4 209 ? 122.016 139.019 139.154 1.00 74.55  ? 46  ILE R C     1 
ATOM   4706 O O     . ILE D 4 209 ? 122.339 138.866 137.970 1.00 74.24  ? 46  ILE R O     1 
ATOM   4707 C CB    . ILE D 4 209 ? 121.401 141.317 140.039 1.00 76.35  ? 46  ILE R CB    1 
ATOM   4708 C CG1   . ILE D 4 209 ? 120.267 142.341 140.053 1.00 77.99  ? 46  ILE R CG1   1 
ATOM   4709 C CG2   . ILE D 4 209 ? 122.545 141.806 139.168 1.00 72.04  ? 46  ILE R CG2   1 
ATOM   4710 C CD1   . ILE D 4 209 ? 120.641 143.653 140.691 1.00 75.17  ? 46  ILE R CD1   1 
ATOM   4711 N N     . PHE D 4 210 ? 122.636 138.367 140.142 1.00 69.23  ? 47  PHE R N     1 
ATOM   4712 C CA    . PHE D 4 210 ? 123.792 137.515 139.883 1.00 72.68  ? 47  PHE R CA    1 
ATOM   4713 C C     . PHE D 4 210 ? 123.442 136.270 139.079 1.00 70.86  ? 47  PHE R C     1 
ATOM   4714 O O     . PHE D 4 210 ? 124.352 135.601 138.579 1.00 67.90  ? 47  PHE R O     1 
ATOM   4715 C CB    . PHE D 4 210 ? 124.456 137.105 141.199 1.00 72.49  ? 47  PHE R CB    1 
ATOM   4716 C CG    . PHE D 4 210 ? 125.595 137.996 141.610 1.00 69.17  ? 47  PHE R CG    1 
ATOM   4717 C CD1   . PHE D 4 210 ? 126.811 137.934 140.949 1.00 67.78  ? 47  PHE R CD1   1 
ATOM   4718 C CD2   . PHE D 4 210 ? 125.456 138.885 142.662 1.00 64.74  ? 47  PHE R CD2   1 
ATOM   4719 C CE1   . PHE D 4 210 ? 127.863 138.748 141.324 1.00 66.67  ? 47  PHE R CE1   1 
ATOM   4720 C CE2   . PHE D 4 210 ? 126.504 139.700 143.042 1.00 63.40  ? 47  PHE R CE2   1 
ATOM   4721 C CZ    . PHE D 4 210 ? 127.709 139.632 142.372 1.00 64.27  ? 47  PHE R CZ    1 
ATOM   4722 N N     . PHE D 4 211 ? 122.155 135.938 138.951 1.00 82.41  ? 48  PHE R N     1 
ATOM   4723 C CA    . PHE D 4 211 ? 121.773 134.785 138.144 1.00 83.31  ? 48  PHE R CA    1 
ATOM   4724 C C     . PHE D 4 211 ? 122.161 134.974 136.684 1.00 81.77  ? 48  PHE R C     1 
ATOM   4725 O O     . PHE D 4 211 ? 122.472 133.998 135.992 1.00 79.61  ? 48  PHE R O     1 
ATOM   4726 C CB    . PHE D 4 211 ? 120.270 134.531 138.267 1.00 80.98  ? 48  PHE R CB    1 
ATOM   4727 N N     . TYR D 4 212 ? 122.149 136.216 136.199 1.00 80.63  ? 49  TYR R N     1 
ATOM   4728 C CA    . TYR D 4 212 ? 122.549 136.526 134.834 1.00 82.50  ? 49  TYR R CA    1 
ATOM   4729 C C     . TYR D 4 212 ? 123.997 136.984 134.721 1.00 80.27  ? 49  TYR R C     1 
ATOM   4730 O O     . TYR D 4 212 ? 124.483 137.168 133.600 1.00 78.43  ? 49  TYR R O     1 
ATOM   4731 C CB    . TYR D 4 212 ? 121.629 137.604 134.248 1.00 82.85  ? 49  TYR R CB    1 
ATOM   4732 C CG    . TYR D 4 212 ? 120.159 137.337 134.475 1.00 83.41  ? 49  TYR R CG    1 
ATOM   4733 C CD1   . TYR D 4 212 ? 119.484 136.381 133.729 1.00 84.34  ? 49  TYR R CD1   1 
ATOM   4734 C CD2   . TYR D 4 212 ? 119.447 138.038 135.440 1.00 81.87  ? 49  TYR R CD2   1 
ATOM   4735 C CE1   . TYR D 4 212 ? 118.141 136.132 133.934 1.00 85.01  ? 49  TYR R CE1   1 
ATOM   4736 C CE2   . TYR D 4 212 ? 118.103 137.796 135.653 1.00 83.45  ? 49  TYR R CE2   1 
ATOM   4737 C CZ    . TYR D 4 212 ? 117.455 136.842 134.897 1.00 86.07  ? 49  TYR R CZ    1 
ATOM   4738 O OH    . TYR D 4 212 ? 116.118 136.596 135.103 1.00 85.23  ? 49  TYR R OH    1 
ATOM   4739 N N     . VAL D 4 213 ? 124.691 137.171 135.835 1.00 73.26  ? 50  VAL R N     1 
ATOM   4740 C CA    . VAL D 4 213 ? 126.082 137.628 135.795 1.00 73.79  ? 50  VAL R CA    1 
ATOM   4741 C C     . VAL D 4 213 ? 126.972 136.457 135.386 1.00 72.27  ? 50  VAL R C     1 
ATOM   4742 O O     . VAL D 4 213 ? 126.941 135.407 136.047 1.00 69.19  ? 50  VAL R O     1 
ATOM   4743 C CB    . VAL D 4 213 ? 126.503 138.189 137.149 1.00 72.53  ? 50  VAL R CB    1 
ATOM   4744 C CG1   . VAL D 4 213 ? 128.002 138.435 137.173 1.00 72.92  ? 50  VAL R CG1   1 
ATOM   4745 C CG2   . VAL D 4 213 ? 125.746 139.470 137.458 1.00 74.99  ? 50  VAL R CG2   1 
ATOM   4746 N N     . PRO D 4 214 ? 127.761 136.588 134.321 1.00 74.46  ? 51  PRO R N     1 
ATOM   4747 C CA    . PRO D 4 214 ? 128.671 135.499 133.946 1.00 73.86  ? 51  PRO R CA    1 
ATOM   4748 C C     . PRO D 4 214 ? 129.791 135.339 134.961 1.00 71.39  ? 51  PRO R C     1 
ATOM   4749 O O     . PRO D 4 214 ? 130.295 136.316 135.519 1.00 69.91  ? 51  PRO R O     1 
ATOM   4750 C CB    . PRO D 4 214 ? 129.209 135.942 132.581 1.00 73.53  ? 51  PRO R CB    1 
ATOM   4751 C CG    . PRO D 4 214 ? 129.097 137.429 132.602 1.00 69.34  ? 51  PRO R CG    1 
ATOM   4752 C CD    . PRO D 4 214 ? 127.873 137.746 133.417 1.00 73.55  ? 51  PRO R CD    1 
ATOM   4753 N N     . SER D 4 215 ? 130.183 134.086 135.194 1.00 61.87  ? 52  SER R N     1 
ATOM   4754 C CA    . SER D 4 215 ? 131.260 133.771 136.134 1.00 59.98  ? 52  SER R CA    1 
ATOM   4755 C C     . SER D 4 215 ? 132.568 133.578 135.365 1.00 60.74  ? 52  SER R C     1 
ATOM   4756 O O     . SER D 4 215 ? 133.157 132.497 135.317 1.00 62.16  ? 52  SER R O     1 
ATOM   4757 C CB    . SER D 4 215 ? 130.904 132.542 136.959 1.00 59.35  ? 52  SER R CB    1 
ATOM   4758 O OG    . SER D 4 215 ? 129.671 132.720 137.633 1.00 57.76  ? 52  SER R OG    1 
ATOM   4759 N N     . SER D 4 216 ? 133.021 134.672 134.754 1.00 61.78  ? 53  SER R N     1 
ATOM   4760 C CA    . SER D 4 216 ? 134.231 134.646 133.943 1.00 60.21  ? 53  SER R CA    1 
ATOM   4761 C C     . SER D 4 216 ? 135.509 134.725 134.769 1.00 59.69  ? 53  SER R C     1 
ATOM   4762 O O     . SER D 4 216 ? 136.589 134.465 134.229 1.00 59.23  ? 53  SER R O     1 
ATOM   4763 C CB    . SER D 4 216 ? 134.208 135.794 132.931 1.00 60.52  ? 53  SER R CB    1 
ATOM   4764 O OG    . SER D 4 216 ? 134.257 137.050 133.585 1.00 64.92  ? 53  SER R OG    1 
ATOM   4765 N N     . LYS D 4 217 ? 135.417 135.072 136.050 1.00 64.00  ? 54  LYS R N     1 
ATOM   4766 C CA    . LYS D 4 217 ? 136.591 135.206 136.899 1.00 59.96  ? 54  LYS R CA    1 
ATOM   4767 C C     . LYS D 4 217 ? 136.287 134.636 138.277 1.00 58.73  ? 54  LYS R C     1 
ATOM   4768 O O     . LYS D 4 217 ? 135.127 134.475 138.664 1.00 58.94  ? 54  LYS R O     1 
ATOM   4769 C CB    . LYS D 4 217 ? 137.040 136.669 137.016 1.00 56.75  ? 54  LYS R CB    1 
ATOM   4770 N N     . SER D 4 218 ? 137.356 134.328 139.017 1.00 59.38  ? 55  SER R N     1 
ATOM   4771 C CA    . SER D 4 218 ? 137.198 133.805 140.370 1.00 60.31  ? 55  SER R CA    1 
ATOM   4772 C C     . SER D 4 218 ? 136.521 134.815 141.286 1.00 58.94  ? 55  SER R C     1 
ATOM   4773 O O     . SER D 4 218 ? 135.839 134.429 142.243 1.00 64.97  ? 55  SER R O     1 
ATOM   4774 C CB    . SER D 4 218 ? 138.559 133.403 140.939 1.00 54.06  ? 55  SER R CB    1 
ATOM   4775 O OG    . SER D 4 218 ? 139.147 132.368 140.172 1.00 61.43  ? 55  SER R OG    1 
ATOM   4776 N N     . PHE D 4 219 ? 136.699 136.109 141.010 1.00 45.60  ? 56  PHE R N     1 
ATOM   4777 C CA    . PHE D 4 219 ? 136.059 137.142 141.816 1.00 42.51  ? 56  PHE R CA    1 
ATOM   4778 C C     . PHE D 4 219 ? 134.541 137.024 141.754 1.00 48.11  ? 56  PHE R C     1 
ATOM   4779 O O     . PHE D 4 219 ? 133.859 137.140 142.779 1.00 50.50  ? 56  PHE R O     1 
ATOM   4780 C CB    . PHE D 4 219 ? 136.522 138.519 141.340 1.00 45.09  ? 56  PHE R CB    1 
ATOM   4781 C CG    . PHE D 4 219 ? 135.877 139.666 142.060 1.00 45.91  ? 56  PHE R CG    1 
ATOM   4782 C CD1   . PHE D 4 219 ? 135.904 139.741 143.441 1.00 51.21  ? 56  PHE R CD1   1 
ATOM   4783 C CD2   . PHE D 4 219 ? 135.261 140.683 141.351 1.00 43.14  ? 56  PHE R CD2   1 
ATOM   4784 C CE1   . PHE D 4 219 ? 135.317 140.802 144.102 1.00 55.54  ? 56  PHE R CE1   1 
ATOM   4785 C CE2   . PHE D 4 219 ? 134.674 141.747 142.006 1.00 45.29  ? 56  PHE R CE2   1 
ATOM   4786 C CZ    . PHE D 4 219 ? 134.702 141.807 143.384 1.00 51.37  ? 56  PHE R CZ    1 
ATOM   4787 N N     . ILE D 4 220 ? 133.997 136.777 140.562 1.00 50.15  ? 57  ILE R N     1 
ATOM   4788 C CA    . ILE D 4 220 ? 132.552 136.627 140.414 1.00 40.66  ? 57  ILE R CA    1 
ATOM   4789 C C     . ILE D 4 220 ? 132.060 135.387 141.150 1.00 44.56  ? 57  ILE R C     1 
ATOM   4790 O O     . ILE D 4 220 ? 130.988 135.399 141.766 1.00 48.75  ? 57  ILE R O     1 
ATOM   4791 C CB    . ILE D 4 220 ? 132.173 136.589 138.923 1.00 51.37  ? 57  ILE R CB    1 
ATOM   4792 C CG1   . ILE D 4 220 ? 132.752 137.803 138.197 1.00 49.93  ? 57  ILE R CG1   1 
ATOM   4793 C CG2   . ILE D 4 220 ? 130.664 136.535 138.761 1.00 53.75  ? 57  ILE R CG2   1 
ATOM   4794 C CD1   . ILE D 4 220 ? 132.265 139.123 138.741 1.00 52.62  ? 57  ILE R CD1   1 
ATOM   4795 N N     . ILE D 4 221 ? 132.823 134.293 141.087 1.00 34.20  ? 58  ILE R N     1 
ATOM   4796 C CA    . ILE D 4 221 ? 132.432 133.071 141.785 1.00 40.43  ? 58  ILE R CA    1 
ATOM   4797 C C     . ILE D 4 221 ? 132.406 133.302 143.290 1.00 43.62  ? 58  ILE R C     1 
ATOM   4798 O O     . ILE D 4 221 ? 131.478 132.867 143.987 1.00 50.09  ? 58  ILE R O     1 
ATOM   4799 C CB    . ILE D 4 221 ? 133.378 131.918 141.404 1.00 38.11  ? 58  ILE R CB    1 
ATOM   4800 C CG1   . ILE D 4 221 ? 133.417 131.746 139.885 1.00 48.32  ? 58  ILE R CG1   1 
ATOM   4801 C CG2   . ILE D 4 221 ? 132.945 130.627 142.081 1.00 39.76  ? 58  ILE R CG2   1 
ATOM   4802 C CD1   . ILE D 4 221 ? 134.737 131.228 139.362 1.00 49.47  ? 58  ILE R CD1   1 
ATOM   4803 N N     . TYR D 4 222 ? 133.423 133.988 143.815 1.00 43.50  ? 59  TYR R N     1 
ATOM   4804 C CA    . TYR D 4 222 ? 133.448 134.293 145.241 1.00 28.33  ? 59  TYR R CA    1 
ATOM   4805 C C     . TYR D 4 222 ? 132.292 135.206 145.627 1.00 35.34  ? 59  TYR R C     1 
ATOM   4806 O O     . TYR D 4 222 ? 131.683 135.034 146.689 1.00 47.37  ? 59  TYR R O     1 
ATOM   4807 C CB    . TYR D 4 222 ? 134.785 134.928 145.622 1.00 38.22  ? 59  TYR R CB    1 
ATOM   4808 C CG    . TYR D 4 222 ? 135.997 134.088 145.285 1.00 37.37  ? 59  TYR R CG    1 
ATOM   4809 C CD1   . TYR D 4 222 ? 135.913 132.703 145.211 1.00 34.65  ? 59  TYR R CD1   1 
ATOM   4810 C CD2   . TYR D 4 222 ? 137.228 134.681 145.043 1.00 30.87  ? 59  TYR R CD2   1 
ATOM   4811 C CE1   . TYR D 4 222 ? 137.019 131.936 144.903 1.00 36.48  ? 59  TYR R CE1   1 
ATOM   4812 C CE2   . TYR D 4 222 ? 138.339 133.922 144.735 1.00 35.53  ? 59  TYR R CE2   1 
ATOM   4813 C CZ    . TYR D 4 222 ? 138.229 132.551 144.666 1.00 39.07  ? 59  TYR R CZ    1 
ATOM   4814 O OH    . TYR D 4 222 ? 139.335 131.792 144.360 1.00 47.51  ? 59  TYR R OH    1 
ATOM   4815 N N     . LEU D 4 223 ? 131.973 136.185 144.774 1.00 39.17  ? 60  LEU R N     1 
ATOM   4816 C CA    . LEU D 4 223 ? 130.837 137.059 145.049 1.00 43.61  ? 60  LEU R CA    1 
ATOM   4817 C C     . LEU D 4 223 ? 129.532 136.277 145.080 1.00 44.61  ? 60  LEU R C     1 
ATOM   4818 O O     . LEU D 4 223 ? 128.674 136.524 145.931 1.00 48.33  ? 60  LEU R O     1 
ATOM   4819 C CB    . LEU D 4 223 ? 130.758 138.177 144.011 1.00 45.12  ? 60  LEU R CB    1 
ATOM   4820 C CG    . LEU D 4 223 ? 131.824 139.269 144.058 1.00 45.19  ? 60  LEU R CG    1 
ATOM   4821 C CD1   . LEU D 4 223 ? 131.587 140.270 142.939 1.00 45.58  ? 60  LEU R CD1   1 
ATOM   4822 C CD2   . LEU D 4 223 ? 131.842 139.957 145.413 1.00 40.98  ? 60  LEU R CD2   1 
ATOM   4823 N N     . LYS D 4 224 ? 129.357 135.335 144.151 1.00 47.83  ? 61  LYS R N     1 
ATOM   4824 C CA    . LYS D 4 224 ? 128.144 134.522 144.138 1.00 47.79  ? 61  LYS R CA    1 
ATOM   4825 C C     . LYS D 4 224 ? 128.052 133.644 145.380 1.00 53.29  ? 61  LYS R C     1 
ATOM   4826 O O     . LYS D 4 224 ? 126.969 133.480 145.957 1.00 59.91  ? 61  LYS R O     1 
ATOM   4827 C CB    . LYS D 4 224 ? 128.098 133.671 142.871 1.00 50.61  ? 61  LYS R CB    1 
ATOM   4828 C CG    . LYS D 4 224 ? 127.770 134.456 141.613 1.00 52.65  ? 61  LYS R CG    1 
ATOM   4829 C CD    . LYS D 4 224 ? 127.679 133.544 140.403 1.00 53.79  ? 61  LYS R CD    1 
ATOM   4830 C CE    . LYS D 4 224 ? 127.305 134.325 139.156 1.00 57.51  ? 61  LYS R CE    1 
ATOM   4831 N NZ    . LYS D 4 224 ? 127.007 133.423 138.010 1.00 58.87  ? 61  LYS R NZ    1 
ATOM   4832 N N     . ASN D 4 225 ? 129.179 133.066 145.803 1.00 37.98  ? 62  ASN R N     1 
ATOM   4833 C CA    . ASN D 4 225 ? 129.181 132.270 147.026 1.00 33.96  ? 62  ASN R CA    1 
ATOM   4834 C C     . ASN D 4 225 ? 128.826 133.124 148.237 1.00 38.71  ? 62  ASN R C     1 
ATOM   4835 O O     . ASN D 4 225 ? 128.074 132.687 149.120 1.00 54.69  ? 62  ASN R O     1 
ATOM   4836 C CB    . ASN D 4 225 ? 130.544 131.608 147.214 1.00 35.18  ? 62  ASN R CB    1 
ATOM   4837 C CG    . ASN D 4 225 ? 130.710 130.364 146.366 1.00 36.68  ? 62  ASN R CG    1 
ATOM   4838 O OD1   . ASN D 4 225 ? 130.496 129.247 146.835 1.00 42.43  ? 62  ASN R OD1   1 
ATOM   4839 N ND2   . ASN D 4 225 ? 131.094 130.552 145.110 1.00 39.05  ? 62  ASN R ND2   1 
ATOM   4840 N N     . ILE D 4 226 ? 129.357 134.347 148.296 1.00 24.71  ? 63  ILE R N     1 
ATOM   4841 C CA    . ILE D 4 226 ? 129.021 135.251 149.392 1.00 32.10  ? 63  ILE R CA    1 
ATOM   4842 C C     . ILE D 4 226 ? 127.549 135.634 149.332 1.00 47.09  ? 63  ILE R C     1 
ATOM   4843 O O     . ILE D 4 226 ? 126.892 135.785 150.366 1.00 49.73  ? 63  ILE R O     1 
ATOM   4844 C CB    . ILE D 4 226 ? 129.937 136.487 149.365 1.00 31.09  ? 63  ILE R CB    1 
ATOM   4845 C CG1   . ILE D 4 226 ? 131.355 136.091 149.764 1.00 38.16  ? 63  ILE R CG1   1 
ATOM   4846 C CG2   . ILE D 4 226 ? 129.423 137.569 150.300 1.00 35.56  ? 63  ILE R CG2   1 
ATOM   4847 C CD1   . ILE D 4 226 ? 132.401 137.035 149.269 1.00 37.48  ? 63  ILE R CD1   1 
ATOM   4848 N N     . VAL D 4 227 ? 127.006 135.790 148.123 1.00 53.64  ? 64  VAL R N     1 
ATOM   4849 C CA    . VAL D 4 227 ? 125.581 136.075 147.974 1.00 48.32  ? 64  VAL R CA    1 
ATOM   4850 C C     . VAL D 4 227 ? 124.751 134.935 148.548 1.00 47.53  ? 64  VAL R C     1 
ATOM   4851 O O     . VAL D 4 227 ? 123.774 135.161 149.272 1.00 50.11  ? 64  VAL R O     1 
ATOM   4852 C CB    . VAL D 4 227 ? 125.236 136.332 146.494 1.00 46.77  ? 64  VAL R CB    1 
ATOM   4853 C CG1   . VAL D 4 227 ? 123.739 136.204 146.265 1.00 52.08  ? 64  VAL R CG1   1 
ATOM   4854 C CG2   . VAL D 4 227 ? 125.715 137.705 146.066 1.00 51.99  ? 64  VAL R CG2   1 
ATOM   4855 N N     . ILE D 4 228 ? 125.130 133.694 148.238 1.00 46.20  ? 65  ILE R N     1 
ATOM   4856 C CA    . ILE D 4 228 ? 124.397 132.538 148.754 1.00 49.26  ? 65  ILE R CA    1 
ATOM   4857 C C     . ILE D 4 228 ? 124.476 132.494 150.277 1.00 50.43  ? 65  ILE R C     1 
ATOM   4858 O O     . ILE D 4 228 ? 123.467 132.293 150.968 1.00 51.10  ? 65  ILE R O     1 
ATOM   4859 C CB    . ILE D 4 228 ? 124.931 131.239 148.125 1.00 50.53  ? 65  ILE R CB    1 
ATOM   4860 C CG1   . ILE D 4 228 ? 124.702 131.242 146.613 1.00 50.53  ? 65  ILE R CG1   1 
ATOM   4861 C CG2   . ILE D 4 228 ? 124.272 130.027 148.763 1.00 50.30  ? 65  ILE R CG2   1 
ATOM   4862 C CD1   . ILE D 4 228 ? 123.244 131.286 146.216 1.00 54.92  ? 65  ILE R CD1   1 
ATOM   4863 N N     . ALA D 4 229 ? 125.682 132.681 150.823 1.00 52.07  ? 66  ALA R N     1 
ATOM   4864 C CA    . ALA D 4 229 ? 125.854 132.637 152.272 1.00 48.71  ? 66  ALA R CA    1 
ATOM   4865 C C     . ALA D 4 229 ? 125.062 133.744 152.957 1.00 55.68  ? 66  ALA R C     1 
ATOM   4866 O O     . ALA D 4 229 ? 124.429 133.517 153.995 1.00 64.54  ? 66  ALA R O     1 
ATOM   4867 C CB    . ALA D 4 229 ? 127.336 132.736 152.629 1.00 44.54  ? 66  ALA R CB    1 
ATOM   4868 N N     . ASP D 4 230 ? 125.081 134.948 152.384 1.00 55.45  ? 67  ASP R N     1 
ATOM   4869 C CA    . ASP D 4 230 ? 124.325 136.064 152.937 1.00 55.35  ? 67  ASP R CA    1 
ATOM   4870 C C     . ASP D 4 230 ? 122.827 135.801 152.875 1.00 58.59  ? 67  ASP R C     1 
ATOM   4871 O O     . ASP D 4 230 ? 122.090 136.146 153.805 1.00 54.07  ? 67  ASP R O     1 
ATOM   4872 C CB    . ASP D 4 230 ? 124.677 137.344 152.183 1.00 60.87  ? 67  ASP R CB    1 
ATOM   4873 C CG    . ASP D 4 230 ? 126.085 137.822 152.472 1.00 62.23  ? 67  ASP R CG    1 
ATOM   4874 O OD1   . ASP D 4 230 ? 126.694 137.326 153.443 1.00 65.46  ? 67  ASP R OD1   1 
ATOM   4875 O OD2   . ASP D 4 230 ? 126.583 138.692 151.728 1.00 58.77  ? 67  ASP R OD2   1 
ATOM   4876 N N     . PHE D 4 231 ? 122.356 135.202 151.779 1.00 65.43  ? 68  PHE R N     1 
ATOM   4877 C CA    . PHE D 4 231 ? 120.940 134.877 151.666 1.00 65.57  ? 68  PHE R CA    1 
ATOM   4878 C C     . PHE D 4 231 ? 120.521 133.876 152.733 1.00 65.45  ? 68  PHE R C     1 
ATOM   4879 O O     . PHE D 4 231 ? 119.472 134.037 153.368 1.00 69.52  ? 68  PHE R O     1 
ATOM   4880 C CB    . PHE D 4 231 ? 120.639 134.336 150.268 1.00 67.77  ? 68  PHE R CB    1 
ATOM   4881 C CG    . PHE D 4 231 ? 119.176 134.287 149.938 1.00 67.26  ? 68  PHE R CG    1 
ATOM   4882 C CD1   . PHE D 4 231 ? 118.408 135.439 149.966 1.00 69.06  ? 68  PHE R CD1   1 
ATOM   4883 C CD2   . PHE D 4 231 ? 118.570 133.090 149.597 1.00 66.76  ? 68  PHE R CD2   1 
ATOM   4884 C CE1   . PHE D 4 231 ? 117.061 135.398 149.663 1.00 73.16  ? 68  PHE R CE1   1 
ATOM   4885 C CE2   . PHE D 4 231 ? 117.224 133.042 149.291 1.00 71.86  ? 68  PHE R CE2   1 
ATOM   4886 C CZ    . PHE D 4 231 ? 116.468 134.198 149.324 1.00 75.25  ? 68  PHE R CZ    1 
ATOM   4887 N N     . VAL D 4 232 ? 121.339 132.846 152.961 1.00 53.74  ? 69  VAL R N     1 
ATOM   4888 C CA    . VAL D 4 232 ? 121.001 131.865 153.991 1.00 53.40  ? 69  VAL R CA    1 
ATOM   4889 C C     . VAL D 4 232 ? 121.055 132.501 155.377 1.00 55.32  ? 69  VAL R C     1 
ATOM   4890 O O     . VAL D 4 232 ? 120.236 132.190 156.251 1.00 58.16  ? 69  VAL R O     1 
ATOM   4891 C CB    . VAL D 4 232 ? 121.920 130.635 153.889 1.00 45.35  ? 69  VAL R CB    1 
ATOM   4892 C CG1   . VAL D 4 232 ? 121.494 129.575 154.891 1.00 52.34  ? 69  VAL R CG1   1 
ATOM   4893 C CG2   . VAL D 4 232 ? 121.883 130.064 152.484 1.00 50.44  ? 69  VAL R CG2   1 
ATOM   4894 N N     . MET D 4 233 ? 122.014 133.403 155.601 1.00 60.31  ? 70  MET R N     1 
ATOM   4895 C CA    . MET D 4 233 ? 122.100 134.098 156.883 1.00 57.18  ? 70  MET R CA    1 
ATOM   4896 C C     . MET D 4 233 ? 120.865 134.958 157.132 1.00 62.26  ? 70  MET R C     1 
ATOM   4897 O O     . MET D 4 233 ? 120.314 134.972 158.241 1.00 66.61  ? 70  MET R O     1 
ATOM   4898 C CB    . MET D 4 233 ? 123.368 134.951 156.913 1.00 61.25  ? 70  MET R CB    1 
ATOM   4899 C CG    . MET D 4 233 ? 123.678 135.574 158.253 1.00 62.28  ? 70  MET R CG    1 
ATOM   4900 S SD    . MET D 4 233 ? 125.030 136.761 158.154 1.00 82.37  ? 70  MET R SD    1 
ATOM   4901 C CE    . MET D 4 233 ? 126.390 135.681 157.722 1.00 60.23  ? 70  MET R CE    1 
ATOM   4902 N N     . SER D 4 234 ? 120.413 135.682 156.107 1.00 69.54  ? 71  SER R N     1 
ATOM   4903 C CA    . SER D 4 234 ? 119.201 136.481 156.244 1.00 69.63  ? 71  SER R CA    1 
ATOM   4904 C C     . SER D 4 234 ? 117.984 135.593 156.467 1.00 69.63  ? 71  SER R C     1 
ATOM   4905 O O     . SER D 4 234 ? 117.078 135.948 157.229 1.00 69.58  ? 71  SER R O     1 
ATOM   4906 C CB    . SER D 4 234 ? 119.011 137.361 155.010 1.00 71.62  ? 71  SER R CB    1 
ATOM   4907 O OG    . SER D 4 234 ? 119.197 136.615 153.820 1.00 76.49  ? 71  SER R OG    1 
ATOM   4908 N N     . LEU D 4 235 ? 117.945 134.432 155.809 1.00 72.39  ? 72  LEU R N     1 
ATOM   4909 C CA    . LEU D 4 235 ? 116.832 133.509 156.000 1.00 71.44  ? 72  LEU R CA    1 
ATOM   4910 C C     . LEU D 4 235 ? 116.813 132.925 157.407 1.00 72.50  ? 72  LEU R C     1 
ATOM   4911 O O     . LEU D 4 235 ? 115.736 132.650 157.946 1.00 77.74  ? 72  LEU R O     1 
ATOM   4912 C CB    . LEU D 4 235 ? 116.896 132.387 154.964 1.00 66.68  ? 72  LEU R CB    1 
ATOM   4913 C CG    . LEU D 4 235 ? 116.449 132.749 153.547 1.00 72.98  ? 72  LEU R CG    1 
ATOM   4914 C CD1   . LEU D 4 235 ? 116.547 131.540 152.629 1.00 74.61  ? 72  LEU R CD1   1 
ATOM   4915 C CD2   . LEU D 4 235 ? 115.035 133.307 153.557 1.00 75.19  ? 72  LEU R CD2   1 
ATOM   4916 N N     . THR D 4 236 ? 117.982 132.713 158.010 1.00 68.06  ? 73  THR R N     1 
ATOM   4917 C CA    . THR D 4 236 ? 118.045 132.151 159.353 1.00 69.12  ? 73  THR R CA    1 
ATOM   4918 C C     . THR D 4 236 ? 117.985 133.208 160.451 1.00 63.69  ? 73  THR R C     1 
ATOM   4919 O O     . THR D 4 236 ? 117.874 132.845 161.627 1.00 61.37  ? 73  THR R O     1 
ATOM   4920 C CB    . THR D 4 236 ? 119.317 131.310 159.524 1.00 69.83  ? 73  THR R CB    1 
ATOM   4921 O OG1   . THR D 4 236 ? 119.196 130.494 160.696 1.00 68.04  ? 73  THR R OG1   1 
ATOM   4922 C CG2   . THR D 4 236 ? 120.535 132.200 159.673 1.00 68.33  ? 73  THR R CG2   1 
ATOM   4923 N N     . PHE D 4 237 ? 118.071 134.493 160.102 1.00 67.36  ? 74  PHE R N     1 
ATOM   4924 C CA    . PHE D 4 237 ? 117.869 135.542 161.103 1.00 71.60  ? 74  PHE R CA    1 
ATOM   4925 C C     . PHE D 4 237 ? 116.521 135.458 161.816 1.00 73.10  ? 74  PHE R C     1 
ATOM   4926 O O     . PHE D 4 237 ? 116.507 135.491 163.061 1.00 72.61  ? 74  PHE R O     1 
ATOM   4927 C CB    . PHE D 4 237 ? 118.044 136.919 160.454 1.00 68.41  ? 74  PHE R CB    1 
ATOM   4928 C CG    . PHE D 4 237 ? 119.473 137.334 160.274 1.00 63.51  ? 74  PHE R CG    1 
ATOM   4929 C CD1   . PHE D 4 237 ? 120.471 136.804 161.072 1.00 64.71  ? 74  PHE R CD1   1 
ATOM   4930 C CD2   . PHE D 4 237 ? 119.815 138.267 159.310 1.00 62.56  ? 74  PHE R CD2   1 
ATOM   4931 C CE1   . PHE D 4 237 ? 121.783 137.192 160.906 1.00 63.86  ? 74  PHE R CE1   1 
ATOM   4932 C CE2   . PHE D 4 237 ? 121.124 138.658 159.140 1.00 67.20  ? 74  PHE R CE2   1 
ATOM   4933 C CZ    . PHE D 4 237 ? 122.109 138.121 159.938 1.00 70.14  ? 74  PHE R CZ    1 
ATOM   4934 N N     . PRO D 4 238 ? 115.374 135.359 161.127 1.00 80.90  ? 75  PRO R N     1 
ATOM   4935 C CA    . PRO D 4 238 ? 114.091 135.406 161.852 1.00 77.60  ? 75  PRO R CA    1 
ATOM   4936 C C     . PRO D 4 238 ? 113.912 134.289 162.862 1.00 76.59  ? 75  PRO R C     1 
ATOM   4937 O O     . PRO D 4 238 ? 113.207 134.484 163.859 1.00 80.76  ? 75  PRO R O     1 
ATOM   4938 C CB    . PRO D 4 238 ? 113.048 135.321 160.728 1.00 76.98  ? 75  PRO R CB    1 
ATOM   4939 C CG    . PRO D 4 238 ? 113.765 134.708 159.587 1.00 75.61  ? 75  PRO R CG    1 
ATOM   4940 C CD    . PRO D 4 238 ? 115.157 135.239 159.674 1.00 77.19  ? 75  PRO R CD    1 
ATOM   4941 N N     . PHE D 4 239 ? 114.520 133.123 162.638 1.00 79.00  ? 76  PHE R N     1 
ATOM   4942 C CA    . PHE D 4 239 ? 114.436 132.052 163.625 1.00 80.80  ? 76  PHE R CA    1 
ATOM   4943 C C     . PHE D 4 239 ? 115.046 132.488 164.952 1.00 81.84  ? 76  PHE R C     1 
ATOM   4944 O O     . PHE D 4 239 ? 114.429 132.335 166.012 1.00 80.12  ? 76  PHE R O     1 
ATOM   4945 C CB    . PHE D 4 239 ? 115.124 130.794 163.097 1.00 80.50  ? 76  PHE R CB    1 
ATOM   4946 C CG    . PHE D 4 239 ? 114.531 130.269 161.822 1.00 80.00  ? 76  PHE R CG    1 
ATOM   4947 C CD1   . PHE D 4 239 ? 113.338 129.567 161.836 1.00 79.83  ? 76  PHE R CD1   1 
ATOM   4948 C CD2   . PHE D 4 239 ? 115.168 130.474 160.610 1.00 81.07  ? 76  PHE R CD2   1 
ATOM   4949 C CE1   . PHE D 4 239 ? 112.789 129.082 160.665 1.00 84.66  ? 76  PHE R CE1   1 
ATOM   4950 C CE2   . PHE D 4 239 ? 114.625 129.991 159.435 1.00 77.43  ? 76  PHE R CE2   1 
ATOM   4951 C CZ    . PHE D 4 239 ? 113.434 129.294 159.463 1.00 81.80  ? 76  PHE R CZ    1 
ATOM   4952 N N     . LYS D 4 240 ? 116.216 133.107 164.920 1.00 89.13  ? 77  LYS R N     1 
ATOM   4953 C CA    . LYS D 4 240 ? 116.796 133.595 166.154 1.00 90.39  ? 77  LYS R CA    1 
ATOM   4954 C C     . LYS D 4 240 ? 115.924 134.657 166.706 1.00 89.22  ? 77  LYS R C     1 
ATOM   4955 O O     . LYS D 4 240 ? 115.599 134.662 167.882 1.00 90.76  ? 77  LYS R O     1 
ATOM   4956 C CB    . LYS D 4 240 ? 118.155 134.212 165.909 1.00 89.31  ? 77  LYS R CB    1 
ATOM   4957 C CG    . LYS D 4 240 ? 118.776 134.799 167.165 1.00 89.83  ? 77  LYS R CG    1 
ATOM   4958 C CD    . LYS D 4 240 ? 118.821 133.780 168.297 1.00 91.94  ? 77  LYS R CD    1 
ATOM   4959 C CE    . LYS D 4 240 ? 120.036 134.002 169.181 1.00 90.48  ? 77  LYS R CE    1 
ATOM   4960 N NZ    . LYS D 4 240 ? 119.711 134.731 170.438 1.00 86.58  ? 77  LYS R NZ    1 
ATOM   4961 N N     . ILE D 4 241 ? 115.540 135.574 165.851 1.00 86.47  ? 78  ILE R N     1 
ATOM   4962 C CA    . ILE D 4 241 ? 114.760 136.715 166.329 1.00 85.71  ? 78  ILE R CA    1 
ATOM   4963 C C     . ILE D 4 241 ? 113.562 136.238 167.141 1.00 87.47  ? 78  ILE R C     1 
ATOM   4964 O O     . ILE D 4 241 ? 113.285 136.743 168.235 1.00 90.73  ? 78  ILE R O     1 
ATOM   4965 C CB    . ILE D 4 241 ? 114.318 137.598 165.150 1.00 86.38  ? 78  ILE R CB    1 
ATOM   4966 C CG1   . ILE D 4 241 ? 115.535 138.169 164.422 1.00 91.08  ? 78  ILE R CG1   1 
ATOM   4967 C CG2   . ILE D 4 241 ? 113.414 138.715 165.638 1.00 85.65  ? 78  ILE R CG2   1 
ATOM   4968 C CD1   . ILE D 4 241 ? 115.205 138.813 163.094 1.00 87.52  ? 78  ILE R CD1   1 
ATOM   4969 N N     . LEU D 4 242 ? 112.834 135.251 166.618 1.00 89.68  ? 79  LEU R N     1 
ATOM   4970 C CA    . LEU D 4 242 ? 111.688 134.720 167.344 1.00 90.92  ? 79  LEU R CA    1 
ATOM   4971 C C     . LEU D 4 242 ? 112.119 133.914 168.562 1.00 92.05  ? 79  LEU R C     1 
ATOM   4972 O O     . LEU D 4 242 ? 111.400 133.881 169.568 1.00 91.07  ? 79  LEU R O     1 
ATOM   4973 C CB    . LEU D 4 242 ? 110.825 133.869 166.415 1.00 88.48  ? 79  LEU R CB    1 
ATOM   4974 C CG    . LEU D 4 242 ? 109.729 134.616 165.653 1.00 89.88  ? 79  LEU R CG    1 
ATOM   4975 C CD1   . LEU D 4 242 ? 109.246 133.797 164.466 1.00 91.38  ? 79  LEU R CD1   1 
ATOM   4976 C CD2   . LEU D 4 242 ? 108.574 134.961 166.579 1.00 91.02  ? 79  LEU R CD2   1 
ATOM   4977 N N     . GLY D 4 243 ? 113.280 133.259 168.494 1.00 93.36  ? 80  GLY R N     1 
ATOM   4978 C CA    . GLY D 4 243 ? 113.749 132.487 169.632 1.00 93.53  ? 80  GLY R CA    1 
ATOM   4979 C C     . GLY D 4 243 ? 114.091 133.351 170.830 1.00 93.74  ? 80  GLY R C     1 
ATOM   4980 O O     . GLY D 4 243 ? 113.727 133.027 171.964 1.00 96.31  ? 80  GLY R O     1 
ATOM   4981 N N     . ASP D 4 244 ? 114.794 134.460 170.602 1.00 97.98  ? 81  ASP R N     1 
ATOM   4982 C CA    . ASP D 4 244 ? 115.167 135.350 171.695 1.00 96.99  ? 81  ASP R CA    1 
ATOM   4983 C C     . ASP D 4 244 ? 114.139 136.445 171.953 1.00 100.05 ? 81  ASP R C     1 
ATOM   4984 O O     . ASP D 4 244 ? 114.294 137.207 172.912 1.00 101.94 ? 81  ASP R O     1 
ATOM   4985 C CB    . ASP D 4 244 ? 116.554 135.966 171.445 1.00 98.04  ? 81  ASP R CB    1 
ATOM   4986 C CG    . ASP D 4 244 ? 116.618 136.816 170.185 1.00 102.10 ? 81  ASP R CG    1 
ATOM   4987 O OD1   . ASP D 4 244 ? 115.568 137.104 169.580 1.00 103.40 ? 81  ASP R OD1   1 
ATOM   4988 O OD2   . ASP D 4 244 ? 117.740 137.202 169.796 1.00 101.92 ? 81  ASP R OD2   1 
ATOM   4989 N N     . SER D 4 245 ? 113.093 136.541 171.126 1.00 103.65 ? 82  SER R N     1 
ATOM   4990 C CA    . SER D 4 245 ? 112.034 137.508 171.392 1.00 103.58 ? 82  SER R CA    1 
ATOM   4991 C C     . SER D 4 245 ? 111.149 137.071 172.551 1.00 104.29 ? 82  SER R C     1 
ATOM   4992 O O     . SER D 4 245 ? 110.613 137.919 173.274 1.00 102.94 ? 82  SER R O     1 
ATOM   4993 C CB    . SER D 4 245 ? 111.192 137.723 170.134 1.00 102.77 ? 82  SER R CB    1 
ATOM   4994 O OG    . SER D 4 245 ? 110.215 136.706 169.997 1.00 102.55 ? 82  SER R OG    1 
ATOM   4995 N N     . GLY D 4 246 ? 110.982 135.763 172.744 1.00 109.93 ? 83  GLY R N     1 
ATOM   4996 C CA    . GLY D 4 246 ? 110.154 135.223 173.797 1.00 108.47 ? 83  GLY R CA    1 
ATOM   4997 C C     . GLY D 4 246 ? 108.770 134.794 173.356 1.00 109.31 ? 83  GLY R C     1 
ATOM   4998 O O     . GLY D 4 246 ? 108.106 134.050 174.088 1.00 110.13 ? 83  GLY R O     1 
ATOM   4999 N N     . LEU D 4 247 ? 108.317 135.241 172.183 1.00 109.75 ? 84  LEU R N     1 
ATOM   5000 C CA    . LEU D 4 247 ? 106.999 134.843 171.702 1.00 110.68 ? 84  LEU R CA    1 
ATOM   5001 C C     . LEU D 4 247 ? 106.992 133.405 171.198 1.00 110.86 ? 84  LEU R C     1 
ATOM   5002 O O     . LEU D 4 247 ? 105.965 132.723 171.292 1.00 109.23 ? 84  LEU R O     1 
ATOM   5003 C CB    . LEU D 4 247 ? 106.532 135.793 170.600 1.00 109.02 ? 84  LEU R CB    1 
ATOM   5004 N N     . GLY D 4 248 ? 108.115 132.931 170.665 1.00 107.79 ? 85  GLY R N     1 
ATOM   5005 C CA    . GLY D 4 248 ? 108.200 131.594 170.130 1.00 108.56 ? 85  GLY R CA    1 
ATOM   5006 C C     . GLY D 4 248 ? 108.224 130.529 171.207 1.00 108.73 ? 85  GLY R C     1 
ATOM   5007 O O     . GLY D 4 248 ? 108.583 130.783 172.361 1.00 109.91 ? 85  GLY R O     1 
ATOM   5008 N N     . PRO D 4 249 ? 107.836 129.310 170.848 1.00 97.92  ? 86  PRO R N     1 
ATOM   5009 C CA    . PRO D 4 249 ? 107.849 128.205 171.810 1.00 97.43  ? 86  PRO R CA    1 
ATOM   5010 C C     . PRO D 4 249 ? 109.265 127.697 172.058 1.00 98.68  ? 86  PRO R C     1 
ATOM   5011 O O     . PRO D 4 249 ? 110.221 128.060 171.371 1.00 99.90  ? 86  PRO R O     1 
ATOM   5012 C CB    . PRO D 4 249 ? 106.989 127.138 171.127 1.00 96.23  ? 86  PRO R CB    1 
ATOM   5013 C CG    . PRO D 4 249 ? 107.176 127.402 169.672 1.00 95.73  ? 86  PRO R CG    1 
ATOM   5014 C CD    . PRO D 4 249 ? 107.299 128.898 169.539 1.00 95.32  ? 86  PRO R CD    1 
ATOM   5015 N N     . TRP D 4 250 ? 109.380 126.838 173.074 1.00 92.01  ? 87  TRP R N     1 
ATOM   5016 C CA    . TRP D 4 250 ? 110.675 126.252 173.407 1.00 93.59  ? 87  TRP R CA    1 
ATOM   5017 C C     . TRP D 4 250 ? 111.191 125.354 172.290 1.00 93.23  ? 87  TRP R C     1 
ATOM   5018 O O     . TRP D 4 250 ? 112.408 125.208 172.122 1.00 92.11  ? 87  TRP R O     1 
ATOM   5019 C CB    . TRP D 4 250 ? 110.575 125.469 174.718 1.00 90.61  ? 87  TRP R CB    1 
ATOM   5020 C CG    . TRP D 4 250 ? 109.812 124.185 174.599 1.00 90.86  ? 87  TRP R CG    1 
ATOM   5021 C CD1   . TRP D 4 250 ? 108.544 124.025 174.118 1.00 91.39  ? 87  TRP R CD1   1 
ATOM   5022 C CD2   . TRP D 4 250 ? 110.267 122.879 174.972 1.00 93.65  ? 87  TRP R CD2   1 
ATOM   5023 N NE1   . TRP D 4 250 ? 108.183 122.701 174.167 1.00 92.17  ? 87  TRP R NE1   1 
ATOM   5024 C CE2   . TRP D 4 250 ? 109.223 121.976 174.687 1.00 94.70  ? 87  TRP R CE2   1 
ATOM   5025 C CE3   . TRP D 4 250 ? 111.456 122.386 175.518 1.00 93.61  ? 87  TRP R CE3   1 
ATOM   5026 C CZ2   . TRP D 4 250 ? 109.333 120.609 174.929 1.00 94.21  ? 87  TRP R CZ2   1 
ATOM   5027 C CZ3   . TRP D 4 250 ? 111.562 121.028 175.758 1.00 94.05  ? 87  TRP R CZ3   1 
ATOM   5028 C CH2   . TRP D 4 250 ? 110.507 120.155 175.464 1.00 94.77  ? 87  TRP R CH2   1 
ATOM   5029 N N     . GLN D 4 251 ? 110.286 124.741 171.522 1.00 91.82  ? 88  GLN R N     1 
ATOM   5030 C CA    . GLN D 4 251 ? 110.709 123.940 170.378 1.00 93.09  ? 88  GLN R CA    1 
ATOM   5031 C C     . GLN D 4 251 ? 111.419 124.801 169.342 1.00 93.42  ? 88  GLN R C     1 
ATOM   5032 O O     . GLN D 4 251 ? 112.426 124.384 168.758 1.00 89.93  ? 88  GLN R O     1 
ATOM   5033 C CB    . GLN D 4 251 ? 109.504 123.233 169.757 1.00 92.17  ? 88  GLN R CB    1 
ATOM   5034 N N     . LEU D 4 252 ? 110.911 126.011 169.101 1.00 93.72  ? 89  LEU R N     1 
ATOM   5035 C CA    . LEU D 4 252 ? 111.593 126.928 168.196 1.00 91.59  ? 89  LEU R CA    1 
ATOM   5036 C C     . LEU D 4 252 ? 112.971 127.302 168.728 1.00 90.02  ? 89  LEU R C     1 
ATOM   5037 O O     . LEU D 4 252 ? 113.937 127.391 167.962 1.00 91.52  ? 89  LEU R O     1 
ATOM   5038 C CB    . LEU D 4 252 ? 110.741 128.178 167.976 1.00 90.04  ? 89  LEU R CB    1 
ATOM   5039 C CG    . LEU D 4 252 ? 111.309 129.238 167.033 1.00 89.97  ? 89  LEU R CG    1 
ATOM   5040 C CD1   . LEU D 4 252 ? 111.689 128.622 165.697 1.00 91.98  ? 89  LEU R CD1   1 
ATOM   5041 C CD2   . LEU D 4 252 ? 110.301 130.355 166.840 1.00 91.26  ? 89  LEU R CD2   1 
ATOM   5042 N N     . ASN D 4 253 ? 113.081 127.522 170.041 1.00 82.30  ? 90  ASN R N     1 
ATOM   5043 C CA    . ASN D 4 253 ? 114.373 127.862 170.628 1.00 82.19  ? 90  ASN R CA    1 
ATOM   5044 C C     . ASN D 4 253 ? 115.375 126.725 170.466 1.00 81.52  ? 90  ASN R C     1 
ATOM   5045 O O     . ASN D 4 253 ? 116.540 126.958 170.123 1.00 81.06  ? 90  ASN R O     1 
ATOM   5046 C CB    . ASN D 4 253 ? 114.202 128.219 172.104 1.00 81.30  ? 90  ASN R CB    1 
ATOM   5047 C CG    . ASN D 4 253 ? 115.509 128.614 172.763 1.00 83.12  ? 90  ASN R CG    1 
ATOM   5048 O OD1   . ASN D 4 253 ? 116.345 129.288 172.158 1.00 82.38  ? 90  ASN R OD1   1 
ATOM   5049 N ND2   . ASN D 4 253 ? 115.695 128.194 174.009 1.00 83.97  ? 90  ASN R ND2   1 
ATOM   5050 N N     . VAL D 4 254 ? 114.941 125.483 170.702 1.00 78.35  ? 91  VAL R N     1 
ATOM   5051 C CA    . VAL D 4 254 ? 115.866 124.362 170.559 1.00 78.73  ? 91  VAL R CA    1 
ATOM   5052 C C     . VAL D 4 254 ? 116.209 124.128 169.091 1.00 78.63  ? 91  VAL R C     1 
ATOM   5053 O O     . VAL D 4 254 ? 117.328 123.710 168.770 1.00 77.74  ? 91  VAL R O     1 
ATOM   5054 C CB    . VAL D 4 254 ? 115.303 123.094 171.236 1.00 80.34  ? 91  VAL R CB    1 
ATOM   5055 C CG1   . VAL D 4 254 ? 114.191 122.467 170.415 1.00 80.95  ? 91  VAL R CG1   1 
ATOM   5056 C CG2   . VAL D 4 254 ? 116.417 122.087 171.481 1.00 79.96  ? 91  VAL R CG2   1 
ATOM   5057 N N     . PHE D 4 255 ? 115.273 124.404 168.177 1.00 79.59  ? 92  PHE R N     1 
ATOM   5058 C CA    . PHE D 4 255 ? 115.587 124.319 166.754 1.00 80.80  ? 92  PHE R CA    1 
ATOM   5059 C C     . PHE D 4 255 ? 116.631 125.355 166.360 1.00 77.82  ? 92  PHE R C     1 
ATOM   5060 O O     . PHE D 4 255 ? 117.544 125.063 165.579 1.00 76.45  ? 92  PHE R O     1 
ATOM   5061 C CB    . PHE D 4 255 ? 114.315 124.497 165.924 1.00 79.14  ? 92  PHE R CB    1 
ATOM   5062 C CG    . PHE D 4 255 ? 114.567 124.619 164.447 1.00 76.97  ? 92  PHE R CG    1 
ATOM   5063 C CD1   . PHE D 4 255 ? 114.813 123.495 163.678 1.00 75.86  ? 92  PHE R CD1   1 
ATOM   5064 C CD2   . PHE D 4 255 ? 114.551 125.859 163.828 1.00 77.82  ? 92  PHE R CD2   1 
ATOM   5065 C CE1   . PHE D 4 255 ? 115.043 123.605 162.320 1.00 74.40  ? 92  PHE R CE1   1 
ATOM   5066 C CE2   . PHE D 4 255 ? 114.781 125.975 162.471 1.00 76.56  ? 92  PHE R CE2   1 
ATOM   5067 C CZ    . PHE D 4 255 ? 115.027 124.847 161.716 1.00 75.30  ? 92  PHE R CZ    1 
ATOM   5068 N N     . VAL D 4 256 ? 116.506 126.575 166.886 1.00 76.02  ? 93  VAL R N     1 
ATOM   5069 C CA    . VAL D 4 256 ? 117.501 127.610 166.618 1.00 71.27  ? 93  VAL R CA    1 
ATOM   5070 C C     . VAL D 4 256 ? 118.854 127.201 167.181 1.00 71.98  ? 93  VAL R C     1 
ATOM   5071 O O     . VAL D 4 256 ? 119.892 127.363 166.527 1.00 72.41  ? 93  VAL R O     1 
ATOM   5072 C CB    . VAL D 4 256 ? 117.034 128.961 167.190 1.00 71.19  ? 93  VAL R CB    1 
ATOM   5073 C CG1   . VAL D 4 256 ? 118.155 129.986 167.120 1.00 72.84  ? 93  VAL R CG1   1 
ATOM   5074 C CG2   . VAL D 4 256 ? 115.814 129.455 166.439 1.00 73.16  ? 93  VAL R CG2   1 
ATOM   5075 N N     . CYS D 4 257 ? 118.864 126.660 168.401 1.00 75.04  ? 94  CYS R N     1 
ATOM   5076 C CA    . CYS D 4 257 ? 120.118 126.242 169.020 1.00 72.96  ? 94  CYS R CA    1 
ATOM   5077 C C     . CYS D 4 257 ? 120.786 125.123 168.229 1.00 69.29  ? 94  CYS R C     1 
ATOM   5078 O O     . CYS D 4 257 ? 122.013 125.104 168.083 1.00 65.33  ? 94  CYS R O     1 
ATOM   5079 C CB    . CYS D 4 257 ? 119.868 125.800 170.461 1.00 79.20  ? 94  CYS R CB    1 
ATOM   5080 S SG    . CYS D 4 257 ? 121.295 125.040 171.265 1.00 81.89  ? 94  CYS R SG    1 
ATOM   5081 N N     . ARG D 4 258 ? 119.997 124.182 167.712 1.00 70.64  ? 95  ARG R N     1 
ATOM   5082 C CA    . ARG D 4 258 ? 120.559 123.004 167.064 1.00 72.23  ? 95  ARG R CA    1 
ATOM   5083 C C     . ARG D 4 258 ? 120.764 123.171 165.564 1.00 74.62  ? 95  ARG R C     1 
ATOM   5084 O O     . ARG D 4 258 ? 121.669 122.544 165.002 1.00 74.22  ? 95  ARG R O     1 
ATOM   5085 C CB    . ARG D 4 258 ? 119.663 121.788 167.317 1.00 69.46  ? 95  ARG R CB    1 
ATOM   5086 N N     . VAL D 4 259 ? 119.953 123.991 164.896 1.00 67.32  ? 96  VAL R N     1 
ATOM   5087 C CA    . VAL D 4 259 ? 119.990 124.055 163.438 1.00 65.69  ? 96  VAL R CA    1 
ATOM   5088 C C     . VAL D 4 259 ? 120.280 125.467 162.946 1.00 68.31  ? 96  VAL R C     1 
ATOM   5089 O O     . VAL D 4 259 ? 121.258 125.693 162.223 1.00 70.32  ? 96  VAL R O     1 
ATOM   5090 C CB    . VAL D 4 259 ? 118.671 123.536 162.834 1.00 67.91  ? 96  VAL R CB    1 
ATOM   5091 C CG1   . VAL D 4 259 ? 118.666 123.734 161.327 1.00 63.83  ? 96  VAL R CG1   1 
ATOM   5092 C CG2   . VAL D 4 259 ? 118.469 122.070 163.182 1.00 68.58  ? 96  VAL R CG2   1 
ATOM   5093 N N     . SER D 4 260 ? 119.429 126.424 163.324 1.00 64.94  ? 97  SER R N     1 
ATOM   5094 C CA    . SER D 4 260 ? 119.507 127.764 162.745 1.00 61.40  ? 97  SER R CA    1 
ATOM   5095 C C     . SER D 4 260 ? 120.830 128.444 163.080 1.00 64.41  ? 97  SER R C     1 
ATOM   5096 O O     . SER D 4 260 ? 121.470 129.045 162.209 1.00 66.40  ? 97  SER R O     1 
ATOM   5097 C CB    . SER D 4 260 ? 118.328 128.609 163.229 1.00 63.59  ? 97  SER R CB    1 
ATOM   5098 O OG    . SER D 4 260 ? 118.418 129.936 162.743 1.00 66.61  ? 97  SER R OG    1 
ATOM   5099 N N     . ALA D 4 261 ? 121.256 128.360 164.343 1.00 53.18  ? 98  ALA R N     1 
ATOM   5100 C CA    . ALA D 4 261 ? 122.502 129.007 164.743 1.00 51.47  ? 98  ALA R CA    1 
ATOM   5101 C C     . ALA D 4 261 ? 123.703 128.378 164.049 1.00 51.13  ? 98  ALA R C     1 
ATOM   5102 O O     . ALA D 4 261 ? 124.631 129.085 163.640 1.00 55.49  ? 98  ALA R O     1 
ATOM   5103 C CB    . ALA D 4 261 ? 122.663 128.946 166.260 1.00 54.09  ? 98  ALA R CB    1 
ATOM   5104 N N     . VAL D 4 262 ? 123.704 127.050 163.912 1.00 44.18  ? 99  VAL R N     1 
ATOM   5105 C CA    . VAL D 4 262 ? 124.814 126.374 163.246 1.00 41.47  ? 99  VAL R CA    1 
ATOM   5106 C C     . VAL D 4 262 ? 124.911 126.816 161.792 1.00 42.63  ? 99  VAL R C     1 
ATOM   5107 O O     . VAL D 4 262 ? 126.003 127.101 161.287 1.00 49.97  ? 99  VAL R O     1 
ATOM   5108 C CB    . VAL D 4 262 ? 124.660 124.848 163.366 1.00 46.87  ? 99  VAL R CB    1 
ATOM   5109 C CG1   . VAL D 4 262 ? 125.917 124.151 162.881 1.00 43.25  ? 99  VAL R CG1   1 
ATOM   5110 C CG2   . VAL D 4 262 ? 124.352 124.460 164.803 1.00 50.99  ? 99  VAL R CG2   1 
ATOM   5111 N N     . LEU D 4 263 ? 123.772 126.884 161.099 1.00 47.41  ? 100 LEU R N     1 
ATOM   5112 C CA    . LEU D 4 263 ? 123.774 127.348 159.716 1.00 42.15  ? 100 LEU R CA    1 
ATOM   5113 C C     . LEU D 4 263 ? 124.230 128.798 159.623 1.00 47.23  ? 100 LEU R C     1 
ATOM   5114 O O     . LEU D 4 263 ? 124.955 129.171 158.693 1.00 52.47  ? 100 LEU R O     1 
ATOM   5115 C CB    . LEU D 4 263 ? 122.383 127.182 159.104 1.00 43.77  ? 100 LEU R CB    1 
ATOM   5116 C CG    . LEU D 4 263 ? 121.901 125.742 158.916 1.00 51.76  ? 100 LEU R CG    1 
ATOM   5117 C CD1   . LEU D 4 263 ? 120.459 125.717 158.433 1.00 53.70  ? 100 LEU R CD1   1 
ATOM   5118 C CD2   . LEU D 4 263 ? 122.809 124.994 157.952 1.00 48.61  ? 100 LEU R CD2   1 
ATOM   5119 N N     . PHE D 4 264 ? 123.811 129.631 160.578 1.00 48.13  ? 101 PHE R N     1 
ATOM   5120 C CA    . PHE D 4 264 ? 124.245 131.024 160.593 1.00 34.46  ? 101 PHE R CA    1 
ATOM   5121 C C     . PHE D 4 264 ? 125.760 131.125 160.726 1.00 32.16  ? 101 PHE R C     1 
ATOM   5122 O O     . PHE D 4 264 ? 126.409 131.896 160.009 1.00 41.94  ? 101 PHE R O     1 
ATOM   5123 C CB    . PHE D 4 264 ? 123.550 131.770 161.732 1.00 39.52  ? 101 PHE R CB    1 
ATOM   5124 C CG    . PHE D 4 264 ? 124.219 133.058 162.115 1.00 39.04  ? 101 PHE R CG    1 
ATOM   5125 C CD1   . PHE D 4 264 ? 124.000 134.210 161.383 1.00 46.03  ? 101 PHE R CD1   1 
ATOM   5126 C CD2   . PHE D 4 264 ? 125.058 133.120 163.214 1.00 46.36  ? 101 PHE R CD2   1 
ATOM   5127 C CE1   . PHE D 4 264 ? 124.612 135.397 161.731 1.00 42.62  ? 101 PHE R CE1   1 
ATOM   5128 C CE2   . PHE D 4 264 ? 125.672 134.303 163.567 1.00 46.23  ? 101 PHE R CE2   1 
ATOM   5129 C CZ    . PHE D 4 264 ? 125.447 135.444 162.826 1.00 42.41  ? 101 PHE R CZ    1 
ATOM   5130 N N     . TYR D 4 265 ? 126.340 130.347 161.641 1.00 37.92  ? 102 TYR R N     1 
ATOM   5131 C CA    . TYR D 4 265 ? 127.790 130.374 161.819 1.00 32.41  ? 102 TYR R CA    1 
ATOM   5132 C C     . TYR D 4 265 ? 128.508 129.845 160.583 1.00 36.39  ? 102 TYR R C     1 
ATOM   5133 O O     . TYR D 4 265 ? 129.552 130.380 160.185 1.00 50.46  ? 102 TYR R O     1 
ATOM   5134 C CB    . TYR D 4 265 ? 128.189 129.572 163.058 1.00 36.93  ? 102 TYR R CB    1 
ATOM   5135 C CG    . TYR D 4 265 ? 127.911 130.286 164.361 1.00 37.51  ? 102 TYR R CG    1 
ATOM   5136 C CD1   . TYR D 4 265 ? 128.539 131.484 164.664 1.00 39.27  ? 102 TYR R CD1   1 
ATOM   5137 C CD2   . TYR D 4 265 ? 127.035 129.753 165.295 1.00 44.44  ? 102 TYR R CD2   1 
ATOM   5138 C CE1   . TYR D 4 265 ? 128.289 132.139 165.853 1.00 39.67  ? 102 TYR R CE1   1 
ATOM   5139 C CE2   . TYR D 4 265 ? 126.779 130.400 166.487 1.00 47.88  ? 102 TYR R CE2   1 
ATOM   5140 C CZ    . TYR D 4 265 ? 127.410 131.591 166.762 1.00 44.95  ? 102 TYR R CZ    1 
ATOM   5141 O OH    . TYR D 4 265 ? 127.161 132.238 167.950 1.00 48.88  ? 102 TYR R OH    1 
ATOM   5142 N N     . VAL D 4 266 ? 127.964 128.794 159.963 1.00 37.92  ? 103 VAL R N     1 
ATOM   5143 C CA    . VAL D 4 266 ? 128.565 128.259 158.743 1.00 38.93  ? 103 VAL R CA    1 
ATOM   5144 C C     . VAL D 4 266 ? 128.581 129.320 157.653 1.00 39.31  ? 103 VAL R C     1 
ATOM   5145 O O     . VAL D 4 266 ? 129.591 129.517 156.971 1.00 42.95  ? 103 VAL R O     1 
ATOM   5146 C CB    . VAL D 4 266 ? 127.820 126.994 158.280 1.00 35.53  ? 103 VAL R CB    1 
ATOM   5147 C CG1   . VAL D 4 266 ? 128.301 126.574 156.902 1.00 36.94  ? 103 VAL R CG1   1 
ATOM   5148 C CG2   . VAL D 4 266 ? 128.037 125.871 159.262 1.00 40.23  ? 103 VAL R CG2   1 
ATOM   5149 N N     . ASN D 4 267 ? 127.460 130.023 157.477 1.00 38.91  ? 104 ASN R N     1 
ATOM   5150 C CA    . ASN D 4 267 ? 127.399 131.065 156.458 1.00 38.03  ? 104 ASN R CA    1 
ATOM   5151 C C     . ASN D 4 267 ? 128.356 132.207 156.776 1.00 44.34  ? 104 ASN R C     1 
ATOM   5152 O O     . ASN D 4 267 ? 129.022 132.736 155.879 1.00 48.58  ? 104 ASN R O     1 
ATOM   5153 C CB    . ASN D 4 267 ? 125.968 131.580 156.320 1.00 43.26  ? 104 ASN R CB    1 
ATOM   5154 C CG    . ASN D 4 267 ? 125.016 130.512 155.827 1.00 50.96  ? 104 ASN R CG    1 
ATOM   5155 O OD1   . ASN D 4 267 ? 125.064 130.109 154.665 1.00 52.41  ? 104 ASN R OD1   1 
ATOM   5156 N ND2   . ASN D 4 267 ? 124.145 130.044 156.711 1.00 51.05  ? 104 ASN R ND2   1 
ATOM   5157 N N     . MET D 4 268 ? 128.445 132.594 158.052 1.00 36.61  ? 105 MET R N     1 
ATOM   5158 C CA    . MET D 4 268 ? 129.358 133.664 158.442 1.00 25.16  ? 105 MET R CA    1 
ATOM   5159 C C     . MET D 4 268 ? 130.800 133.306 158.112 1.00 26.78  ? 105 MET R C     1 
ATOM   5160 O O     . MET D 4 268 ? 131.540 134.111 157.534 1.00 41.80  ? 105 MET R O     1 
ATOM   5161 C CB    . MET D 4 268 ? 129.215 133.956 159.936 1.00 22.34  ? 105 MET R CB    1 
ATOM   5162 C CG    . MET D 4 268 ? 130.320 134.836 160.492 1.00 33.66  ? 105 MET R CG    1 
ATOM   5163 S SD    . MET D 4 268 ? 130.442 134.769 162.287 1.00 27.27  ? 105 MET R SD    1 
ATOM   5164 C CE    . MET D 4 268 ? 128.960 135.651 162.756 1.00 35.68  ? 105 MET R CE    1 
ATOM   5165 N N     . TYR D 4 269 ? 131.219 132.092 158.465 1.00 19.42  ? 106 TYR R N     1 
ATOM   5166 C CA    . TYR D 4 269 ? 132.611 131.724 158.236 1.00 19.93  ? 106 TYR R CA    1 
ATOM   5167 C C     . TYR D 4 269 ? 132.891 131.431 156.768 1.00 34.42  ? 106 TYR R C     1 
ATOM   5168 O O     . TYR D 4 269 ? 134.011 131.668 156.301 1.00 35.25  ? 106 TYR R O     1 
ATOM   5169 C CB    . TYR D 4 269 ? 132.992 130.548 159.132 1.00 16.80  ? 106 TYR R CB    1 
ATOM   5170 C CG    . TYR D 4 269 ? 133.191 130.985 160.565 1.00 31.73  ? 106 TYR R CG    1 
ATOM   5171 C CD1   . TYR D 4 269 ? 134.284 131.762 160.925 1.00 23.05  ? 106 TYR R CD1   1 
ATOM   5172 C CD2   . TYR D 4 269 ? 132.271 130.656 161.549 1.00 37.56  ? 106 TYR R CD2   1 
ATOM   5173 C CE1   . TYR D 4 269 ? 134.465 132.180 162.228 1.00 22.45  ? 106 TYR R CE1   1 
ATOM   5174 C CE2   . TYR D 4 269 ? 132.442 131.071 162.855 1.00 29.78  ? 106 TYR R CE2   1 
ATOM   5175 C CZ    . TYR D 4 269 ? 133.541 131.833 163.188 1.00 27.69  ? 106 TYR R CZ    1 
ATOM   5176 O OH    . TYR D 4 269 ? 133.718 132.246 164.488 1.00 36.30  ? 106 TYR R OH    1 
ATOM   5177 N N     . VAL D 4 270 ? 131.893 130.958 156.017 1.00 34.61  ? 107 VAL R N     1 
ATOM   5178 C CA    . VAL D 4 270 ? 132.040 130.860 154.568 1.00 22.11  ? 107 VAL R CA    1 
ATOM   5179 C C     . VAL D 4 270 ? 132.265 132.241 153.968 1.00 40.90  ? 107 VAL R C     1 
ATOM   5180 O O     . VAL D 4 270 ? 133.142 132.431 153.116 1.00 56.98  ? 107 VAL R O     1 
ATOM   5181 C CB    . VAL D 4 270 ? 130.811 130.166 153.951 1.00 23.19  ? 107 VAL R CB    1 
ATOM   5182 C CG1   . VAL D 4 270 ? 130.746 130.428 152.460 1.00 32.31  ? 107 VAL R CG1   1 
ATOM   5183 C CG2   . VAL D 4 270 ? 130.853 128.673 154.216 1.00 32.96  ? 107 VAL R CG2   1 
ATOM   5184 N N     . SER D 4 271 ? 131.484 133.229 154.413 1.00 29.96  ? 108 SER R N     1 
ATOM   5185 C CA    . SER D 4 271 ? 131.659 134.591 153.920 1.00 17.27  ? 108 SER R CA    1 
ATOM   5186 C C     . SER D 4 271 ? 133.032 135.139 154.287 1.00 24.59  ? 108 SER R C     1 
ATOM   5187 O O     . SER D 4 271 ? 133.665 135.829 153.483 1.00 46.95  ? 108 SER R O     1 
ATOM   5188 C CB    . SER D 4 271 ? 130.554 135.494 154.466 1.00 26.69  ? 108 SER R CB    1 
ATOM   5189 O OG    . SER D 4 271 ? 130.810 135.858 155.811 1.00 37.73  ? 108 SER R OG    1 
ATOM   5190 N N     . ILE D 4 272 ? 133.509 134.845 155.498 1.00 12.80  ? 109 ILE R N     1 
ATOM   5191 C CA    . ILE D 4 272 ? 134.829 135.322 155.914 1.00 18.22  ? 109 ILE R CA    1 
ATOM   5192 C C     . ILE D 4 272 ? 135.922 134.698 155.049 1.00 28.65  ? 109 ILE R C     1 
ATOM   5193 O O     . ILE D 4 272 ? 136.841 135.384 154.576 1.00 33.03  ? 109 ILE R O     1 
ATOM   5194 C CB    . ILE D 4 272 ? 135.056 135.031 157.409 1.00 13.05  ? 109 ILE R CB    1 
ATOM   5195 C CG1   . ILE D 4 272 ? 134.252 136.005 158.270 1.00 20.13  ? 109 ILE R CG1   1 
ATOM   5196 C CG2   . ILE D 4 272 ? 136.535 135.108 157.754 1.00 8.49   ? 109 ILE R CG2   1 
ATOM   5197 C CD1   . ILE D 4 272 ? 134.024 135.524 159.684 1.00 25.01  ? 109 ILE R CD1   1 
ATOM   5198 N N     . VAL D 4 273 ? 135.836 133.384 154.828 1.00 14.62  ? 110 VAL R N     1 
ATOM   5199 C CA    . VAL D 4 273 ? 136.834 132.698 154.013 1.00 10.58  ? 110 VAL R CA    1 
ATOM   5200 C C     . VAL D 4 273 ? 136.811 133.230 152.587 1.00 20.55  ? 110 VAL R C     1 
ATOM   5201 O O     . VAL D 4 273 ? 137.858 133.395 151.951 1.00 28.74  ? 110 VAL R O     1 
ATOM   5202 C CB    . VAL D 4 273 ? 136.609 131.175 154.061 1.00 10.56  ? 110 VAL R CB    1 
ATOM   5203 C CG1   . VAL D 4 273 ? 137.446 130.474 153.005 1.00 28.76  ? 110 VAL R CG1   1 
ATOM   5204 C CG2   . VAL D 4 273 ? 136.941 130.636 155.443 1.00 18.61  ? 110 VAL R CG2   1 
ATOM   5205 N N     . PHE D 4 274 ? 135.621 133.531 152.065 1.00 22.82  ? 111 PHE R N     1 
ATOM   5206 C CA    . PHE D 4 274 ? 135.543 134.043 150.702 1.00 25.35  ? 111 PHE R CA    1 
ATOM   5207 C C     . PHE D 4 274 ? 135.999 135.496 150.614 1.00 28.66  ? 111 PHE R C     1 
ATOM   5208 O O     . PHE D 4 274 ? 136.509 135.916 149.572 1.00 31.94  ? 111 PHE R O     1 
ATOM   5209 C CB    . PHE D 4 274 ? 134.127 133.872 150.160 1.00 18.49  ? 111 PHE R CB    1 
ATOM   5210 C CG    . PHE D 4 274 ? 133.892 132.534 149.523 1.00 26.75  ? 111 PHE R CG    1 
ATOM   5211 C CD1   . PHE D 4 274 ? 134.556 132.180 148.362 1.00 24.47  ? 111 PHE R CD1   1 
ATOM   5212 C CD2   . PHE D 4 274 ? 133.028 131.620 150.098 1.00 28.72  ? 111 PHE R CD2   1 
ATOM   5213 C CE1   . PHE D 4 274 ? 134.351 130.946 147.778 1.00 31.89  ? 111 PHE R CE1   1 
ATOM   5214 C CE2   . PHE D 4 274 ? 132.821 130.383 149.521 1.00 29.15  ? 111 PHE R CE2   1 
ATOM   5215 C CZ    . PHE D 4 274 ? 133.482 130.047 148.358 1.00 28.36  ? 111 PHE R CZ    1 
ATOM   5216 N N     . PHE D 4 275 ? 135.841 136.273 151.689 1.00 25.27  ? 112 PHE R N     1 
ATOM   5217 C CA    . PHE D 4 275 ? 136.459 137.595 151.733 1.00 10.85  ? 112 PHE R CA    1 
ATOM   5218 C C     . PHE D 4 275 ? 137.975 137.482 151.667 1.00 14.59  ? 112 PHE R C     1 
ATOM   5219 O O     . PHE D 4 275 ? 138.636 138.239 150.945 1.00 37.81  ? 112 PHE R O     1 
ATOM   5220 C CB    . PHE D 4 275 ? 136.044 138.338 153.003 1.00 21.76  ? 112 PHE R CB    1 
ATOM   5221 C CG    . PHE D 4 275 ? 134.595 138.720 153.043 1.00 24.94  ? 112 PHE R CG    1 
ATOM   5222 C CD1   . PHE D 4 275 ? 133.903 138.999 151.878 1.00 24.39  ? 112 PHE R CD1   1 
ATOM   5223 C CD2   . PHE D 4 275 ? 133.926 138.813 154.252 1.00 22.15  ? 112 PHE R CD2   1 
ATOM   5224 C CE1   . PHE D 4 275 ? 132.570 139.354 151.918 1.00 28.74  ? 112 PHE R CE1   1 
ATOM   5225 C CE2   . PHE D 4 275 ? 132.594 139.166 154.297 1.00 18.08  ? 112 PHE R CE2   1 
ATOM   5226 C CZ    . PHE D 4 275 ? 131.915 139.437 153.129 1.00 21.04  ? 112 PHE R CZ    1 
ATOM   5227 N N     . GLY D 4 276 ? 138.542 136.537 152.418 1.00 20.70  ? 113 GLY R N     1 
ATOM   5228 C CA    . GLY D 4 276 ? 139.973 136.292 152.318 1.00 14.60  ? 113 GLY R CA    1 
ATOM   5229 C C     . GLY D 4 276 ? 140.388 135.853 150.926 1.00 22.62  ? 113 GLY R C     1 
ATOM   5230 O O     . GLY D 4 276 ? 141.440 136.256 150.421 1.00 28.47  ? 113 GLY R O     1 
ATOM   5231 N N     . LEU D 4 277 ? 139.564 135.020 150.288 1.00 26.28  ? 114 LEU R N     1 
ATOM   5232 C CA    . LEU D 4 277 ? 139.851 134.579 148.926 1.00 22.51  ? 114 LEU R CA    1 
ATOM   5233 C C     . LEU D 4 277 ? 139.812 135.742 147.942 1.00 26.11  ? 114 LEU R C     1 
ATOM   5234 O O     . LEU D 4 277 ? 140.641 135.813 147.030 1.00 30.95  ? 114 LEU R O     1 
ATOM   5235 C CB    . LEU D 4 277 ? 138.868 133.487 148.507 1.00 20.00  ? 114 LEU R CB    1 
ATOM   5236 C CG    . LEU D 4 277 ? 139.064 132.118 149.160 1.00 24.55  ? 114 LEU R CG    1 
ATOM   5237 C CD1   . LEU D 4 277 ? 138.037 131.124 148.644 1.00 31.50  ? 114 LEU R CD1   1 
ATOM   5238 C CD2   . LEU D 4 277 ? 140.476 131.608 148.924 1.00 24.63  ? 114 LEU R CD2   1 
ATOM   5239 N N     . ILE D 4 278 ? 138.851 136.655 148.100 1.00 26.41  ? 115 ILE R N     1 
ATOM   5240 C CA    . ILE D 4 278 ? 138.800 137.838 147.243 1.00 20.88  ? 115 ILE R CA    1 
ATOM   5241 C C     . ILE D 4 278 ? 140.028 138.708 147.462 1.00 26.05  ? 115 ILE R C     1 
ATOM   5242 O O     . ILE D 4 278 ? 140.602 139.248 146.508 1.00 42.53  ? 115 ILE R O     1 
ATOM   5243 C CB    . ILE D 4 278 ? 137.502 138.632 147.480 1.00 9.62   ? 115 ILE R CB    1 
ATOM   5244 C CG1   . ILE D 4 278 ? 136.289 137.835 147.012 1.00 20.59  ? 115 ILE R CG1   1 
ATOM   5245 C CG2   . ILE D 4 278 ? 137.552 139.974 146.774 1.00 20.05  ? 115 ILE R CG2   1 
ATOM   5246 C CD1   . ILE D 4 278 ? 134.982 138.471 147.389 1.00 24.80  ? 115 ILE R CD1   1 
ATOM   5247 N N     . SER D 4 279 ? 140.441 138.873 148.720 1.00 23.49  ? 116 SER R N     1 
ATOM   5248 C CA    . SER D 4 279 ? 141.647 139.648 148.994 1.00 12.58  ? 116 SER R CA    1 
ATOM   5249 C C     . SER D 4 279 ? 142.862 139.023 148.320 1.00 22.24  ? 116 SER R C     1 
ATOM   5250 O O     . SER D 4 279 ? 143.667 139.725 147.697 1.00 42.10  ? 116 SER R O     1 
ATOM   5251 C CB    . SER D 4 279 ? 141.866 139.765 150.501 1.00 22.92  ? 116 SER R CB    1 
ATOM   5252 O OG    . SER D 4 279 ? 142.339 138.545 151.044 1.00 35.43  ? 116 SER R OG    1 
ATOM   5253 N N     . PHE D 4 280 ? 142.998 137.697 148.415 1.00 28.37  ? 117 PHE R N     1 
ATOM   5254 C CA    . PHE D 4 280 ? 144.122 137.025 147.769 1.00 28.90  ? 117 PHE R CA    1 
ATOM   5255 C C     . PHE D 4 280 ? 144.046 137.138 146.251 1.00 33.93  ? 117 PHE R C     1 
ATOM   5256 O O     . PHE D 4 280 ? 145.074 137.302 145.587 1.00 41.82  ? 117 PHE R O     1 
ATOM   5257 C CB    . PHE D 4 280 ? 144.181 135.557 148.184 1.00 33.94  ? 117 PHE R CB    1 
ATOM   5258 C CG    . PHE D 4 280 ? 145.257 134.783 147.480 1.00 40.51  ? 117 PHE R CG    1 
ATOM   5259 C CD1   . PHE D 4 280 ? 146.593 135.029 147.750 1.00 40.68  ? 117 PHE R CD1   1 
ATOM   5260 C CD2   . PHE D 4 280 ? 144.936 133.825 146.535 1.00 41.21  ? 117 PHE R CD2   1 
ATOM   5261 C CE1   . PHE D 4 280 ? 147.587 134.326 147.099 1.00 44.75  ? 117 PHE R CE1   1 
ATOM   5262 C CE2   . PHE D 4 280 ? 145.926 133.120 145.880 1.00 41.86  ? 117 PHE R CE2   1 
ATOM   5263 C CZ    . PHE D 4 280 ? 147.253 133.370 146.163 1.00 43.50  ? 117 PHE R CZ    1 
ATOM   5264 N N     . ASP D 4 281 ? 142.844 137.028 145.681 1.00 29.69  ? 118 ASP R N     1 
ATOM   5265 C CA    . ASP D 4 281 ? 142.697 137.139 144.234 1.00 34.40  ? 118 ASP R CA    1 
ATOM   5266 C C     . ASP D 4 281 ? 143.068 138.532 143.748 1.00 42.63  ? 118 ASP R C     1 
ATOM   5267 O O     . ASP D 4 281 ? 143.742 138.682 142.722 1.00 49.99  ? 118 ASP R O     1 
ATOM   5268 C CB    . ASP D 4 281 ? 141.267 136.791 143.824 1.00 31.09  ? 118 ASP R CB    1 
ATOM   5269 C CG    . ASP D 4 281 ? 141.081 136.768 142.320 1.00 45.33  ? 118 ASP R CG    1 
ATOM   5270 O OD1   . ASP D 4 281 ? 142.070 136.510 141.602 1.00 47.65  ? 118 ASP R OD1   1 
ATOM   5271 O OD2   . ASP D 4 281 ? 139.947 137.010 141.855 1.00 50.18  ? 118 ASP R OD2   1 
ATOM   5272 N N     . ARG D 4 282 ? 142.634 139.566 144.471 1.00 36.35  ? 119 ARG R N     1 
ATOM   5273 C CA    . ARG D 4 282 ? 143.005 140.929 144.109 1.00 26.31  ? 119 ARG R CA    1 
ATOM   5274 C C     . ARG D 4 282 ? 144.506 141.141 144.250 1.00 29.84  ? 119 ARG R C     1 
ATOM   5275 O O     . ARG D 4 282 ? 145.129 141.805 143.412 1.00 51.68  ? 119 ARG R O     1 
ATOM   5276 C CB    . ARG D 4 282 ? 142.230 141.927 144.968 1.00 23.89  ? 119 ARG R CB    1 
ATOM   5277 C CG    . ARG D 4 282 ? 140.746 141.979 144.651 1.00 27.11  ? 119 ARG R CG    1 
ATOM   5278 C CD    . ARG D 4 282 ? 139.992 142.836 145.649 1.00 20.56  ? 119 ARG R CD    1 
ATOM   5279 N NE    . ARG D 4 282 ? 138.629 143.109 145.209 1.00 19.56  ? 119 ARG R NE    1 
ATOM   5280 C CZ    . ARG D 4 282 ? 137.628 143.419 146.022 1.00 29.53  ? 119 ARG R CZ    1 
ATOM   5281 N NH1   . ARG D 4 282 ? 137.801 143.497 147.331 1.00 30.35  ? 119 ARG R NH1   1 
ATOM   5282 N NH2   . ARG D 4 282 ? 136.424 143.654 145.510 1.00 37.07  ? 119 ARG R NH2   1 
ATOM   5283 N N     . TYR D 4 283 ? 145.106 140.577 145.302 1.00 21.43  ? 120 TYR R N     1 
ATOM   5284 C CA    . TYR D 4 283 ? 146.554 140.659 145.464 1.00 29.17  ? 120 TYR R CA    1 
ATOM   5285 C C     . TYR D 4 283 ? 147.276 139.995 144.298 1.00 33.16  ? 120 TYR R C     1 
ATOM   5286 O O     . TYR D 4 283 ? 148.248 140.542 143.766 1.00 46.65  ? 120 TYR R O     1 
ATOM   5287 C CB    . TYR D 4 283 ? 146.957 140.018 146.793 1.00 38.73  ? 120 TYR R CB    1 
ATOM   5288 C CG    . TYR D 4 283 ? 148.443 139.824 146.980 1.00 28.14  ? 120 TYR R CG    1 
ATOM   5289 C CD1   . TYR D 4 283 ? 149.236 140.845 147.481 1.00 35.42  ? 120 TYR R CD1   1 
ATOM   5290 C CD2   . TYR D 4 283 ? 149.049 138.613 146.676 1.00 36.65  ? 120 TYR R CD2   1 
ATOM   5291 C CE1   . TYR D 4 283 ? 150.593 140.672 147.659 1.00 46.18  ? 120 TYR R CE1   1 
ATOM   5292 C CE2   . TYR D 4 283 ? 150.406 138.431 146.852 1.00 45.48  ? 120 TYR R CE2   1 
ATOM   5293 C CZ    . TYR D 4 283 ? 151.173 139.465 147.344 1.00 50.16  ? 120 TYR R CZ    1 
ATOM   5294 O OH    . TYR D 4 283 ? 152.525 139.292 147.523 1.00 52.23  ? 120 TYR R OH    1 
ATOM   5295 N N     . TYR D 4 284 ? 146.804 138.820 143.881 1.00 34.93  ? 121 TYR R N     1 
ATOM   5296 C CA    . TYR D 4 284 ? 147.407 138.123 142.750 1.00 39.50  ? 121 TYR R CA    1 
ATOM   5297 C C     . TYR D 4 284 ? 147.262 138.924 141.462 1.00 46.72  ? 121 TYR R C     1 
ATOM   5298 O O     . TYR D 4 284 ? 148.200 139.001 140.660 1.00 45.69  ? 121 TYR R O     1 
ATOM   5299 C CB    . TYR D 4 284 ? 146.770 136.741 142.598 1.00 42.03  ? 121 TYR R CB    1 
ATOM   5300 C CG    . TYR D 4 284 ? 147.385 135.882 141.519 1.00 45.97  ? 121 TYR R CG    1 
ATOM   5301 C CD1   . TYR D 4 284 ? 148.495 135.094 141.780 1.00 45.26  ? 121 TYR R CD1   1 
ATOM   5302 C CD2   . TYR D 4 284 ? 146.845 135.849 140.239 1.00 50.70  ? 121 TYR R CD2   1 
ATOM   5303 C CE1   . TYR D 4 284 ? 149.055 134.304 140.798 1.00 51.86  ? 121 TYR R CE1   1 
ATOM   5304 C CE2   . TYR D 4 284 ? 147.400 135.063 139.250 1.00 50.30  ? 121 TYR R CE2   1 
ATOM   5305 C CZ    . TYR D 4 284 ? 148.505 134.292 139.535 1.00 56.25  ? 121 TYR R CZ    1 
ATOM   5306 O OH    . TYR D 4 284 ? 149.063 133.505 138.554 1.00 54.29  ? 121 TYR R OH    1 
ATOM   5307 N N     . LYS D 4 285 ? 146.091 139.525 141.246 1.00 43.33  ? 122 LYS R N     1 
ATOM   5308 C CA    . LYS D 4 285 ? 145.842 140.229 139.993 1.00 35.23  ? 122 LYS R CA    1 
ATOM   5309 C C     . LYS D 4 285 ? 146.611 141.543 139.921 1.00 39.67  ? 122 LYS R C     1 
ATOM   5310 O O     . LYS D 4 285 ? 147.049 141.951 138.839 1.00 48.97  ? 122 LYS R O     1 
ATOM   5311 C CB    . LYS D 4 285 ? 144.344 140.475 139.820 1.00 30.36  ? 122 LYS R CB    1 
ATOM   5312 N N     . ILE D 4 286 ? 146.787 142.221 141.052 1.00 29.47  ? 123 ILE R N     1 
ATOM   5313 C CA    . ILE D 4 286 ? 147.399 143.547 141.048 1.00 34.30  ? 123 ILE R CA    1 
ATOM   5314 C C     . ILE D 4 286 ? 148.894 143.478 141.334 1.00 35.48  ? 123 ILE R C     1 
ATOM   5315 O O     . ILE D 4 286 ? 149.712 143.936 140.532 1.00 48.07  ? 123 ILE R O     1 
ATOM   5316 C CB    . ILE D 4 286 ? 146.674 144.460 142.059 1.00 26.61  ? 123 ILE R CB    1 
ATOM   5317 C CG1   . ILE D 4 286 ? 145.220 144.672 141.633 1.00 19.28  ? 123 ILE R CG1   1 
ATOM   5318 C CG2   . ILE D 4 286 ? 147.397 145.789 142.192 1.00 38.51  ? 123 ILE R CG2   1 
ATOM   5319 C CD1   . ILE D 4 286 ? 144.290 144.999 142.777 1.00 28.44  ? 123 ILE R CD1   1 
ATOM   5320 N N     . VAL D 4 287 ? 149.275 142.910 142.480 1.00 25.37  ? 124 VAL R N     1 
ATOM   5321 C CA    . VAL D 4 287 ? 150.673 142.910 142.898 1.00 32.87  ? 124 VAL R CA    1 
ATOM   5322 C C     . VAL D 4 287 ? 151.548 142.028 142.014 1.00 48.36  ? 124 VAL R C     1 
ATOM   5323 O O     . VAL D 4 287 ? 152.739 142.324 141.848 1.00 51.78  ? 124 VAL R O     1 
ATOM   5324 C CB    . VAL D 4 287 ? 150.765 142.480 144.373 1.00 33.99  ? 124 VAL R CB    1 
ATOM   5325 C CG1   . VAL D 4 287 ? 152.213 142.399 144.837 1.00 36.41  ? 124 VAL R CG1   1 
ATOM   5326 C CG2   . VAL D 4 287 ? 149.980 143.444 145.247 1.00 37.35  ? 124 VAL R CG2   1 
ATOM   5327 N N     . LYS D 4 288 ? 150.984 140.977 141.409 1.00 51.83  ? 125 LYS R N     1 
ATOM   5328 C CA    . LYS D 4 288 ? 151.738 139.986 140.646 1.00 49.53  ? 125 LYS R CA    1 
ATOM   5329 C C     . LYS D 4 288 ? 152.846 139.394 141.510 1.00 55.08  ? 125 LYS R C     1 
ATOM   5330 O O     . LYS D 4 288 ? 154.027 139.704 141.306 1.00 54.10  ? 125 LYS R O     1 
ATOM   5331 C CB    . LYS D 4 288 ? 152.328 140.601 139.374 1.00 46.30  ? 125 LYS R CB    1 
ATOM   5332 C CG    . LYS D 4 288 ? 151.343 141.406 138.541 1.00 44.01  ? 125 LYS R CG    1 
ATOM   5333 C CD    . LYS D 4 288 ? 150.309 140.515 137.876 1.00 47.16  ? 125 LYS R CD    1 
ATOM   5334 C CE    . LYS D 4 288 ? 149.512 141.286 136.837 1.00 44.76  ? 125 LYS R CE    1 
ATOM   5335 N NZ    . LYS D 4 288 ? 148.471 140.440 136.190 1.00 48.78  ? 125 LYS R NZ    1 
ATOM   5336 N N     . PRO D 4 289 ? 152.507 138.551 142.483 1.00 56.35  ? 126 PRO R N     1 
ATOM   5337 C CA    . PRO D 4 289 ? 153.525 138.029 143.400 1.00 56.41  ? 126 PRO R CA    1 
ATOM   5338 C C     . PRO D 4 289 ? 154.487 137.075 142.707 1.00 65.64  ? 126 PRO R C     1 
ATOM   5339 O O     . PRO D 4 289 ? 154.212 136.529 141.636 1.00 62.15  ? 126 PRO R O     1 
ATOM   5340 C CB    . PRO D 4 289 ? 152.700 137.301 144.464 1.00 56.51  ? 126 PRO R CB    1 
ATOM   5341 C CG    . PRO D 4 289 ? 151.457 136.897 143.749 1.00 60.64  ? 126 PRO R CG    1 
ATOM   5342 C CD    . PRO D 4 289 ? 151.171 137.999 142.766 1.00 54.37  ? 126 PRO R CD    1 
ATOM   5343 N N     . LEU D 4 290 ? 155.642 136.884 143.349 1.00 76.28  ? 127 LEU R N     1 
ATOM   5344 C CA    . LEU D 4 290 ? 156.671 136.003 142.809 1.00 73.09  ? 127 LEU R CA    1 
ATOM   5345 C C     . LEU D 4 290 ? 156.269 134.534 142.852 1.00 73.87  ? 127 LEU R C     1 
ATOM   5346 O O     . LEU D 4 290 ? 156.890 133.716 142.166 1.00 73.05  ? 127 LEU R O     1 
ATOM   5347 C CB    . LEU D 4 290 ? 157.984 136.203 143.568 1.00 71.01  ? 127 LEU R CB    1 
ATOM   5348 N N     . TRP D 4 291 ? 155.252 134.179 143.636 1.00 76.20  ? 128 TRP R N     1 
ATOM   5349 C CA    . TRP D 4 291 ? 154.767 132.804 143.730 1.00 76.72  ? 128 TRP R CA    1 
ATOM   5350 C C     . TRP D 4 291 ? 153.531 132.582 142.869 1.00 78.34  ? 128 TRP R C     1 
ATOM   5351 O O     . TRP D 4 291 ? 152.614 131.849 143.252 1.00 76.10  ? 128 TRP R O     1 
ATOM   5352 C CB    . TRP D 4 291 ? 154.486 132.431 145.183 1.00 74.40  ? 128 TRP R CB    1 
ATOM   5353 C CG    . TRP D 4 291 ? 153.572 133.378 145.898 1.00 75.86  ? 128 TRP R CG    1 
ATOM   5354 C CD1   . TRP D 4 291 ? 152.208 133.367 145.888 1.00 76.82  ? 128 TRP R CD1   1 
ATOM   5355 C CD2   . TRP D 4 291 ? 153.959 134.460 146.753 1.00 78.56  ? 128 TRP R CD2   1 
ATOM   5356 N NE1   . TRP D 4 291 ? 151.721 134.384 146.672 1.00 76.75  ? 128 TRP R NE1   1 
ATOM   5357 C CE2   . TRP D 4 291 ? 152.775 135.069 147.216 1.00 79.00  ? 128 TRP R CE2   1 
ATOM   5358 C CE3   . TRP D 4 291 ? 155.190 134.976 147.168 1.00 78.31  ? 128 TRP R CE3   1 
ATOM   5359 C CZ2   . TRP D 4 291 ? 152.787 136.168 148.072 1.00 75.98  ? 128 TRP R CZ2   1 
ATOM   5360 C CZ3   . TRP D 4 291 ? 155.199 136.067 148.018 1.00 79.27  ? 128 TRP R CZ3   1 
ATOM   5361 C CH2   . TRP D 4 291 ? 154.006 136.651 148.461 1.00 78.11  ? 128 TRP R CH2   1 
ATOM   5362 N N     . THR D 4 292 ? 153.487 133.210 141.692 1.00 84.25  ? 129 THR R N     1 
ATOM   5363 C CA    . THR D 4 292 ? 152.336 133.111 140.804 1.00 84.44  ? 129 THR R CA    1 
ATOM   5364 C C     . THR D 4 292 ? 152.120 131.707 140.255 1.00 84.95  ? 129 THR R C     1 
ATOM   5365 O O     . THR D 4 292 ? 151.051 131.441 139.695 1.00 80.22  ? 129 THR R O     1 
ATOM   5366 C CB    . THR D 4 292 ? 152.484 134.094 139.641 1.00 79.17  ? 129 THR R CB    1 
ATOM   5367 N N     . SER D 4 293 ? 153.098 130.809 140.396 1.00 89.88  ? 130 SER R N     1 
ATOM   5368 C CA    . SER D 4 293 ? 152.963 129.451 139.881 1.00 87.49  ? 130 SER R CA    1 
ATOM   5369 C C     . SER D 4 293 ? 151.869 128.653 140.580 1.00 90.48  ? 130 SER R C     1 
ATOM   5370 O O     . SER D 4 293 ? 151.468 127.607 140.060 1.00 90.62  ? 130 SER R O     1 
ATOM   5371 C CB    . SER D 4 293 ? 154.297 128.711 140.004 1.00 86.16  ? 130 SER R CB    1 
ATOM   5372 N N     . PHE D 4 294 ? 151.386 129.111 141.738 1.00 99.87  ? 131 PHE R N     1 
ATOM   5373 C CA    . PHE D 4 294 ? 150.303 128.407 142.419 1.00 99.08  ? 131 PHE R CA    1 
ATOM   5374 C C     . PHE D 4 294 ? 149.032 128.403 141.579 1.00 100.62 ? 131 PHE R C     1 
ATOM   5375 O O     . PHE D 4 294 ? 148.334 127.385 141.500 1.00 98.83  ? 131 PHE R O     1 
ATOM   5376 C CB    . PHE D 4 294 ? 150.043 129.040 143.785 1.00 96.00  ? 131 PHE R CB    1 
ATOM   5377 N N     . ILE D 4 295 ? 148.716 129.537 140.949 1.00 91.37  ? 132 ILE R N     1 
ATOM   5378 C CA    . ILE D 4 295 ? 147.578 129.670 140.042 1.00 89.69  ? 132 ILE R CA    1 
ATOM   5379 C C     . ILE D 4 295 ? 146.278 129.320 140.756 1.00 94.66  ? 132 ILE R C     1 
ATOM   5380 O O     . ILE D 4 295 ? 145.483 128.513 140.260 1.00 94.66  ? 132 ILE R O     1 
ATOM   5381 C CB    . ILE D 4 295 ? 147.762 128.803 138.783 1.00 88.64  ? 132 ILE R CB    1 
ATOM   5382 N N     . GLN D 4 296 ? 146.056 129.919 141.929 1.00 89.58  ? 133 GLN R N     1 
ATOM   5383 C CA    . GLN D 4 296 ? 144.788 129.725 142.626 1.00 85.36  ? 133 GLN R CA    1 
ATOM   5384 C C     . GLN D 4 296 ? 143.631 130.325 141.837 1.00 81.83  ? 133 GLN R C     1 
ATOM   5385 O O     . GLN D 4 296 ? 142.540 129.746 141.781 1.00 78.09  ? 133 GLN R O     1 
ATOM   5386 C CB    . GLN D 4 296 ? 144.857 130.334 144.026 1.00 83.57  ? 133 GLN R CB    1 
ATOM   5387 C CG    . GLN D 4 296 ? 145.834 129.640 144.962 1.00 82.04  ? 133 GLN R CG    1 
ATOM   5388 C CD    . GLN D 4 296 ? 145.383 128.245 145.345 1.00 81.94  ? 133 GLN R CD    1 
ATOM   5389 O OE1   . GLN D 4 296 ? 144.200 128.006 145.586 1.00 80.31  ? 133 GLN R OE1   1 
ATOM   5390 N NE2   . GLN D 4 296 ? 146.327 127.313 145.403 1.00 83.74  ? 133 GLN R NE2   1 
ATOM   5391 N N     . SER D 4 297 ? 143.850 131.487 141.220 1.00 81.02  ? 134 SER R N     1 
ATOM   5392 C CA    . SER D 4 297 ? 142.824 132.160 140.424 1.00 80.32  ? 134 SER R CA    1 
ATOM   5393 C C     . SER D 4 297 ? 142.720 131.457 139.072 1.00 79.65  ? 134 SER R C     1 
ATOM   5394 O O     . SER D 4 297 ? 143.214 131.925 138.043 1.00 76.57  ? 134 SER R O     1 
ATOM   5395 C CB    . SER D 4 297 ? 143.148 133.640 140.268 1.00 77.08  ? 134 SER R CB    1 
ATOM   5396 O OG    . SER D 4 297 ? 143.453 134.229 141.520 1.00 76.85  ? 134 SER R OG    1 
ATOM   5397 N N     . VAL D 4 298 ? 142.058 130.304 139.086 1.00 81.16  ? 135 VAL R N     1 
ATOM   5398 C CA    . VAL D 4 298 ? 141.857 129.472 137.909 1.00 79.97  ? 135 VAL R CA    1 
ATOM   5399 C C     . VAL D 4 298 ? 140.469 128.848 137.995 1.00 78.83  ? 135 VAL R C     1 
ATOM   5400 O O     . VAL D 4 298 ? 139.704 129.113 138.925 1.00 81.53  ? 135 VAL R O     1 
ATOM   5401 C CB    . VAL D 4 298 ? 142.940 128.381 137.771 1.00 77.06  ? 135 VAL R CB    1 
ATOM   5402 N N     . SER D 4 299 ? 140.136 128.025 136.997 1.00 73.96  ? 136 SER R N     1 
ATOM   5403 C CA    . SER D 4 299 ? 138.867 127.306 137.030 1.00 77.51  ? 136 SER R CA    1 
ATOM   5404 C C     . SER D 4 299 ? 138.766 126.406 138.255 1.00 77.65  ? 136 SER R C     1 
ATOM   5405 O O     . SER D 4 299 ? 137.673 126.227 138.807 1.00 71.01  ? 136 SER R O     1 
ATOM   5406 C CB    . SER D 4 299 ? 138.694 126.485 135.752 1.00 76.05  ? 136 SER R CB    1 
ATOM   5407 N N     . TYR D 4 300 ? 139.895 125.849 138.704 1.00 74.52  ? 137 TYR R N     1 
ATOM   5408 C CA    . TYR D 4 300 ? 139.897 124.990 139.883 1.00 70.30  ? 137 TYR R CA    1 
ATOM   5409 C C     . TYR D 4 300 ? 139.392 125.713 141.123 1.00 68.73  ? 137 TYR R C     1 
ATOM   5410 O O     . TYR D 4 300 ? 138.941 125.053 142.067 1.00 67.69  ? 137 TYR R O     1 
ATOM   5411 C CB    . TYR D 4 300 ? 141.304 124.446 140.134 1.00 69.44  ? 137 TYR R CB    1 
ATOM   5412 N N     . SER D 4 301 ? 139.455 127.048 141.141 1.00 68.64  ? 138 SER R N     1 
ATOM   5413 C CA    . SER D 4 301 ? 138.900 127.801 142.261 1.00 66.73  ? 138 SER R CA    1 
ATOM   5414 C C     . SER D 4 301 ? 137.433 127.458 142.477 1.00 65.96  ? 138 SER R C     1 
ATOM   5415 O O     . SER D 4 301 ? 136.963 127.417 143.621 1.00 72.03  ? 138 SER R O     1 
ATOM   5416 C CB    . SER D 4 301 ? 139.069 129.302 142.028 1.00 66.38  ? 138 SER R CB    1 
ATOM   5417 O OG    . SER D 4 301 ? 138.082 129.792 141.136 1.00 66.53  ? 138 SER R OG    1 
ATOM   5418 N N     . LYS D 4 302 ? 136.698 127.195 141.391 1.00 65.35  ? 139 LYS R N     1 
ATOM   5419 C CA    . LYS D 4 302 ? 135.320 126.734 141.525 1.00 67.95  ? 139 LYS R CA    1 
ATOM   5420 C C     . LYS D 4 302 ? 135.249 125.516 142.434 1.00 64.00  ? 139 LYS R C     1 
ATOM   5421 O O     . LYS D 4 302 ? 134.484 125.493 143.406 1.00 62.45  ? 139 LYS R O     1 
ATOM   5422 C CB    . LYS D 4 302 ? 134.732 126.412 140.150 1.00 66.15  ? 139 LYS R CB    1 
ATOM   5423 C CG    . LYS D 4 302 ? 134.345 127.631 139.333 1.00 65.57  ? 139 LYS R CG    1 
ATOM   5424 C CD    . LYS D 4 302 ? 133.655 127.228 138.040 1.00 64.74  ? 139 LYS R CD    1 
ATOM   5425 C CE    . LYS D 4 302 ? 133.212 128.446 137.247 1.00 71.14  ? 139 LYS R CE    1 
ATOM   5426 N NZ    . LYS D 4 302 ? 132.531 128.067 135.978 1.00 72.09  ? 139 LYS R NZ    1 
ATOM   5427 N N     . LEU D 4 303 ? 136.075 124.506 142.153 1.00 66.15  ? 140 LEU R N     1 
ATOM   5428 C CA    . LEU D 4 303 ? 136.174 123.368 143.058 1.00 67.07  ? 140 LEU R CA    1 
ATOM   5429 C C     . LEU D 4 303 ? 136.609 123.828 144.441 1.00 69.57  ? 140 LEU R C     1 
ATOM   5430 O O     . LEU D 4 303 ? 136.011 123.443 145.454 1.00 70.57  ? 140 LEU R O     1 
ATOM   5431 C CB    . LEU D 4 303 ? 137.149 122.332 142.496 1.00 66.17  ? 140 LEU R CB    1 
ATOM   5432 N N     . LEU D 4 304 ? 137.622 124.698 144.497 1.00 62.88  ? 141 LEU R N     1 
ATOM   5433 C CA    . LEU D 4 304 ? 138.031 125.275 145.772 1.00 59.70  ? 141 LEU R CA    1 
ATOM   5434 C C     . LEU D 4 304 ? 136.837 125.874 146.496 1.00 51.21  ? 141 LEU R C     1 
ATOM   5435 O O     . LEU D 4 304 ? 136.697 125.715 147.715 1.00 57.96  ? 141 LEU R O     1 
ATOM   5436 C CB    . LEU D 4 304 ? 139.113 126.333 145.552 1.00 61.58  ? 141 LEU R CB    1 
ATOM   5437 C CG    . LEU D 4 304 ? 139.647 127.034 146.802 1.00 59.38  ? 141 LEU R CG    1 
ATOM   5438 C CD1   . LEU D 4 304 ? 140.321 126.039 147.732 1.00 59.86  ? 141 LEU R CD1   1 
ATOM   5439 C CD2   . LEU D 4 304 ? 140.603 128.155 146.424 1.00 56.38  ? 141 LEU R CD2   1 
ATOM   5440 N N     . SER D 4 305 ? 135.938 126.522 145.747 1.00 43.32  ? 142 SER R N     1 
ATOM   5441 C CA    . SER D 4 305 ? 134.745 127.101 146.352 1.00 47.75  ? 142 SER R CA    1 
ATOM   5442 C C     . SER D 4 305 ? 133.984 126.058 147.158 1.00 53.62  ? 142 SER R C     1 
ATOM   5443 O O     . SER D 4 305 ? 133.719 126.252 148.351 1.00 51.30  ? 142 SER R O     1 
ATOM   5444 C CB    . SER D 4 305 ? 133.852 127.708 145.270 1.00 54.79  ? 142 SER R CB    1 
ATOM   5445 O OG    . SER D 4 305 ? 134.534 128.723 144.554 1.00 59.53  ? 142 SER R OG    1 
ATOM   5446 N N     . VAL D 4 306 ? 133.668 124.917 146.540 1.00 59.91  ? 143 VAL R N     1 
ATOM   5447 C CA    . VAL D 4 306 ? 132.970 123.882 147.294 1.00 56.94  ? 143 VAL R CA    1 
ATOM   5448 C C     . VAL D 4 306 ? 133.898 123.297 148.350 1.00 56.05  ? 143 VAL R C     1 
ATOM   5449 O O     . VAL D 4 306 ? 133.469 122.993 149.471 1.00 52.06  ? 143 VAL R O     1 
ATOM   5450 C CB    . VAL D 4 306 ? 132.382 122.806 146.356 1.00 57.35  ? 143 VAL R CB    1 
ATOM   5451 C CG1   . VAL D 4 306 ? 133.447 121.857 145.830 1.00 56.89  ? 143 VAL R CG1   1 
ATOM   5452 C CG2   . VAL D 4 306 ? 131.278 122.033 147.065 1.00 60.07  ? 143 VAL R CG2   1 
ATOM   5453 N N     . ILE D 4 307 ? 135.194 123.194 148.034 1.00 56.91  ? 144 ILE R N     1 
ATOM   5454 C CA    . ILE D 4 307 ? 136.168 122.746 149.024 1.00 56.78  ? 144 ILE R CA    1 
ATOM   5455 C C     . ILE D 4 307 ? 136.189 123.702 150.203 1.00 55.26  ? 144 ILE R C     1 
ATOM   5456 O O     . ILE D 4 307 ? 136.549 123.319 151.322 1.00 56.64  ? 144 ILE R O     1 
ATOM   5457 C CB    . ILE D 4 307 ? 137.563 122.605 148.384 1.00 54.79  ? 144 ILE R CB    1 
ATOM   5458 N N     . VAL D 4 308 ? 135.806 124.959 149.974 1.00 55.73  ? 145 VAL R N     1 
ATOM   5459 C CA    . VAL D 4 308 ? 135.568 125.876 151.081 1.00 53.34  ? 145 VAL R CA    1 
ATOM   5460 C C     . VAL D 4 308 ? 134.315 125.459 151.843 1.00 56.14  ? 145 VAL R C     1 
ATOM   5461 O O     . VAL D 4 308 ? 134.374 125.121 153.032 1.00 50.80  ? 145 VAL R O     1 
ATOM   5462 C CB    . VAL D 4 308 ? 135.465 127.322 150.562 1.00 48.83  ? 145 VAL R CB    1 
ATOM   5463 C CG1   . VAL D 4 308 ? 134.872 128.233 151.615 1.00 45.47  ? 145 VAL R CG1   1 
ATOM   5464 C CG2   . VAL D 4 308 ? 136.835 127.829 150.136 1.00 47.55  ? 145 VAL R CG2   1 
ATOM   5465 N N     . TRP D 4 309 ? 133.177 125.413 151.143 1.00 48.38  ? 146 TRP R N     1 
ATOM   5466 C CA    . TRP D 4 309 ? 131.883 125.236 151.797 1.00 39.64  ? 146 TRP R CA    1 
ATOM   5467 C C     . TRP D 4 309 ? 131.872 123.989 152.672 1.00 45.71  ? 146 TRP R C     1 
ATOM   5468 O O     . TRP D 4 309 ? 131.751 124.072 153.902 1.00 52.81  ? 146 TRP R O     1 
ATOM   5469 C CB    . TRP D 4 309 ? 130.777 125.157 150.742 1.00 37.71  ? 146 TRP R CB    1 
ATOM   5470 C CG    . TRP D 4 309 ? 130.191 126.480 150.363 1.00 42.15  ? 146 TRP R CG    1 
ATOM   5471 C CD1   . TRP D 4 309 ? 130.581 127.285 149.333 1.00 42.41  ? 146 TRP R CD1   1 
ATOM   5472 C CD2   . TRP D 4 309 ? 129.097 127.149 151.001 1.00 42.97  ? 146 TRP R CD2   1 
ATOM   5473 N NE1   . TRP D 4 309 ? 129.802 128.416 149.294 1.00 38.54  ? 146 TRP R NE1   1 
ATOM   5474 C CE2   . TRP D 4 309 ? 128.883 128.356 150.308 1.00 36.78  ? 146 TRP R CE2   1 
ATOM   5475 C CE3   . TRP D 4 309 ? 128.279 126.845 152.094 1.00 40.52  ? 146 TRP R CE3   1 
ATOM   5476 C CZ2   . TRP D 4 309 ? 127.886 129.258 150.670 1.00 33.46  ? 146 TRP R CZ2   1 
ATOM   5477 C CZ3   . TRP D 4 309 ? 127.291 127.742 152.452 1.00 43.56  ? 146 TRP R CZ3   1 
ATOM   5478 C CH2   . TRP D 4 309 ? 127.103 128.934 151.743 1.00 44.08  ? 146 TRP R CH2   1 
ATOM   5479 N N     . MET D 4 310 ? 132.057 122.824 152.045 1.00 59.39  ? 147 MET R N     1 
ATOM   5480 C CA    . MET D 4 310 ? 132.014 121.562 152.771 1.00 58.68  ? 147 MET R CA    1 
ATOM   5481 C C     . MET D 4 310 ? 132.958 121.570 153.961 1.00 61.80  ? 147 MET R C     1 
ATOM   5482 O O     . MET D 4 310 ? 132.657 120.955 154.992 1.00 66.18  ? 147 MET R O     1 
ATOM   5483 C CB    . MET D 4 310 ? 132.358 120.403 151.833 1.00 58.61  ? 147 MET R CB    1 
ATOM   5484 C CG    . MET D 4 310 ? 131.430 120.264 150.636 1.00 64.81  ? 147 MET R CG    1 
ATOM   5485 S SD    . MET D 4 310 ? 129.759 119.764 151.090 1.00 75.24  ? 147 MET R SD    1 
ATOM   5486 C CE    . MET D 4 310 ? 128.861 121.291 150.823 1.00 65.15  ? 147 MET R CE    1 
ATOM   5487 N N     . LEU D 4 311 ? 134.086 122.282 153.853 1.00 53.47  ? 148 LEU R N     1 
ATOM   5488 C CA    . LEU D 4 311 ? 135.030 122.327 154.963 1.00 51.12  ? 148 LEU R CA    1 
ATOM   5489 C C     . LEU D 4 311 ? 134.342 122.804 156.235 1.00 51.61  ? 148 LEU R C     1 
ATOM   5490 O O     . LEU D 4 311 ? 134.349 122.106 157.257 1.00 52.51  ? 148 LEU R O     1 
ATOM   5491 C CB    . LEU D 4 311 ? 136.212 123.230 154.612 1.00 49.94  ? 148 LEU R CB    1 
ATOM   5492 N N     . MET D 4 312 ? 133.675 123.960 156.170 1.00 45.78  ? 149 MET R N     1 
ATOM   5493 C CA    . MET D 4 312 ? 132.939 124.423 157.340 1.00 43.99  ? 149 MET R CA    1 
ATOM   5494 C C     . MET D 4 312 ? 131.779 123.497 157.664 1.00 54.91  ? 149 MET R C     1 
ATOM   5495 O O     . MET D 4 312 ? 131.449 123.309 158.842 1.00 62.15  ? 149 MET R O     1 
ATOM   5496 C CB    . MET D 4 312 ? 132.467 125.863 157.141 1.00 41.91  ? 149 MET R CB    1 
ATOM   5497 C CG    . MET D 4 312 ? 133.522 126.890 157.527 1.00 43.91  ? 149 MET R CG    1 
ATOM   5498 S SD    . MET D 4 312 ? 134.939 126.969 156.421 1.00 57.07  ? 149 MET R SD    1 
ATOM   5499 C CE    . MET D 4 312 ? 134.227 127.842 155.040 1.00 58.64  ? 149 MET R CE    1 
ATOM   5500 N N     . LEU D 4 313 ? 131.172 122.883 156.646 1.00 51.94  ? 150 LEU R N     1 
ATOM   5501 C CA    . LEU D 4 313 ? 130.188 121.843 156.917 1.00 53.00  ? 150 LEU R CA    1 
ATOM   5502 C C     . LEU D 4 313 ? 130.823 120.715 157.718 1.00 61.60  ? 150 LEU R C     1 
ATOM   5503 O O     . LEU D 4 313 ? 130.270 120.266 158.729 1.00 60.52  ? 150 LEU R O     1 
ATOM   5504 C CB    . LEU D 4 313 ? 129.597 121.320 155.608 1.00 44.00  ? 150 LEU R CB    1 
ATOM   5505 N N     . LEU D 4 314 ? 132.022 120.287 157.311 1.00 62.42  ? 151 LEU R N     1 
ATOM   5506 C CA    . LEU D 4 314 ? 132.734 119.265 158.066 1.00 60.74  ? 151 LEU R CA    1 
ATOM   5507 C C     . LEU D 4 314 ? 133.095 119.743 159.463 1.00 64.75  ? 151 LEU R C     1 
ATOM   5508 O O     . LEU D 4 314 ? 133.340 118.916 160.347 1.00 67.93  ? 151 LEU R O     1 
ATOM   5509 C CB    . LEU D 4 314 ? 133.996 118.836 157.314 1.00 55.17  ? 151 LEU R CB    1 
ATOM   5510 N N     . LEU D 4 315 ? 133.134 121.057 159.681 1.00 55.88  ? 152 LEU R N     1 
ATOM   5511 C CA    . LEU D 4 315 ? 133.404 121.596 161.004 1.00 51.88  ? 152 LEU R CA    1 
ATOM   5512 C C     . LEU D 4 315 ? 132.140 121.863 161.807 1.00 56.73  ? 152 LEU R C     1 
ATOM   5513 O O     . LEU D 4 315 ? 132.239 122.231 162.983 1.00 61.02  ? 152 LEU R O     1 
ATOM   5514 C CB    . LEU D 4 315 ? 134.216 122.891 160.894 1.00 49.11  ? 152 LEU R CB    1 
ATOM   5515 C CG    . LEU D 4 315 ? 135.698 122.725 160.556 1.00 53.52  ? 152 LEU R CG    1 
ATOM   5516 C CD1   . LEU D 4 315 ? 136.308 124.058 160.151 1.00 53.53  ? 152 LEU R CD1   1 
ATOM   5517 C CD2   . LEU D 4 315 ? 136.449 122.121 161.732 1.00 54.18  ? 152 LEU R CD2   1 
ATOM   5518 N N     . ALA D 4 316 ? 130.959 121.691 161.209 1.00 58.09  ? 153 ALA R N     1 
ATOM   5519 C CA    . ALA D 4 316 ? 129.715 122.000 161.897 1.00 54.78  ? 153 ALA R CA    1 
ATOM   5520 C C     . ALA D 4 316 ? 128.629 120.948 161.735 1.00 64.56  ? 153 ALA R C     1 
ATOM   5521 O O     . ALA D 4 316 ? 127.597 121.050 162.407 1.00 70.06  ? 153 ALA R O     1 
ATOM   5522 C CB    . ALA D 4 316 ? 129.167 123.355 161.428 1.00 49.97  ? 153 ALA R CB    1 
ATOM   5523 N N     . VAL D 4 317 ? 128.817 119.955 160.861 1.00 67.82  ? 154 VAL R N     1 
ATOM   5524 C CA    . VAL D 4 317 ? 127.838 118.870 160.757 1.00 68.15  ? 154 VAL R CA    1 
ATOM   5525 C C     . VAL D 4 317 ? 127.671 118.135 162.078 1.00 71.55  ? 154 VAL R C     1 
ATOM   5526 O O     . VAL D 4 317 ? 126.524 117.863 162.467 1.00 68.04  ? 154 VAL R O     1 
ATOM   5527 C CB    . VAL D 4 317 ? 128.197 117.942 159.588 1.00 64.66  ? 154 VAL R CB    1 
ATOM   5528 N N     . PRO D 4 318 ? 128.731 117.772 162.814 1.00 74.03  ? 155 PRO R N     1 
ATOM   5529 C CA    . PRO D 4 318 ? 128.517 117.153 164.132 1.00 74.03  ? 155 PRO R CA    1 
ATOM   5530 C C     . PRO D 4 318 ? 127.759 118.033 165.110 1.00 71.01  ? 155 PRO R C     1 
ATOM   5531 O O     . PRO D 4 318 ? 127.022 117.498 165.947 1.00 80.63  ? 155 PRO R O     1 
ATOM   5532 C CB    . PRO D 4 318 ? 129.944 116.877 164.624 1.00 73.82  ? 155 PRO R CB    1 
ATOM   5533 C CG    . PRO D 4 318 ? 130.721 116.700 163.375 1.00 75.22  ? 155 PRO R CG    1 
ATOM   5534 C CD    . PRO D 4 318 ? 130.159 117.734 162.443 1.00 68.49  ? 155 PRO R CD    1 
ATOM   5535 N N     . ASN D 4 319 ? 127.902 119.355 165.032 1.00 58.28  ? 156 ASN R N     1 
ATOM   5536 C CA    . ASN D 4 319 ? 127.228 120.256 165.957 1.00 61.79  ? 156 ASN R CA    1 
ATOM   5537 C C     . ASN D 4 319 ? 125.710 120.218 165.833 1.00 65.76  ? 156 ASN R C     1 
ATOM   5538 O O     . ASN D 4 319 ? 125.019 120.677 166.748 1.00 70.05  ? 156 ASN R O     1 
ATOM   5539 C CB    . ASN D 4 319 ? 127.718 121.693 165.750 1.00 70.12  ? 156 ASN R CB    1 
ATOM   5540 C CG    . ASN D 4 319 ? 129.211 121.837 165.972 1.00 73.23  ? 156 ASN R CG    1 
ATOM   5541 O OD1   . ASN D 4 319 ? 129.896 120.869 166.297 1.00 78.52  ? 156 ASN R OD1   1 
ATOM   5542 N ND2   . ASN D 4 319 ? 129.721 123.051 165.799 1.00 65.80  ? 156 ASN R ND2   1 
ATOM   5543 N N     . ILE D 4 320 ? 125.179 119.684 164.736 1.00 67.80  ? 157 ILE R N     1 
ATOM   5544 C CA    . ILE D 4 320 ? 123.735 119.565 164.586 1.00 70.53  ? 157 ILE R CA    1 
ATOM   5545 C C     . ILE D 4 320 ? 123.226 118.214 165.084 1.00 71.23  ? 157 ILE R C     1 
ATOM   5546 O O     . ILE D 4 320 ? 122.182 118.151 165.740 1.00 67.94  ? 157 ILE R O     1 
ATOM   5547 C CB    . ILE D 4 320 ? 123.332 119.796 163.120 1.00 68.01  ? 157 ILE R CB    1 
ATOM   5548 C CG1   . ILE D 4 320 ? 123.780 121.181 162.654 1.00 67.23  ? 157 ILE R CG1   1 
ATOM   5549 C CG2   . ILE D 4 320 ? 121.829 119.643 162.945 1.00 69.60  ? 157 ILE R CG2   1 
ATOM   5550 C CD1   . ILE D 4 320 ? 123.668 121.387 161.161 1.00 67.05  ? 157 ILE R CD1   1 
ATOM   5551 N N     . ILE D 4 321 ? 123.949 117.133 164.798 1.00 79.65  ? 158 ILE R N     1 
ATOM   5552 C CA    . ILE D 4 321 ? 123.498 115.804 165.193 1.00 79.10  ? 158 ILE R CA    1 
ATOM   5553 C C     . ILE D 4 321 ? 123.814 115.497 166.655 1.00 75.05  ? 158 ILE R C     1 
ATOM   5554 O O     . ILE D 4 321 ? 123.107 114.704 167.284 1.00 78.90  ? 158 ILE R O     1 
ATOM   5555 C CB    . ILE D 4 321 ? 124.109 114.740 164.265 1.00 77.75  ? 158 ILE R CB    1 
ATOM   5556 C CG1   . ILE D 4 321 ? 125.635 114.844 164.265 1.00 74.31  ? 158 ILE R CG1   1 
ATOM   5557 C CG2   . ILE D 4 321 ? 123.566 114.891 162.852 1.00 75.18  ? 158 ILE R CG2   1 
ATOM   5558 C CD1   . ILE D 4 321 ? 126.323 113.733 163.503 1.00 76.84  ? 158 ILE R CD1   1 
ATOM   5559 N N     . LEU D 4 322 ? 124.858 116.108 167.214 1.00 68.35  ? 159 LEU R N     1 
ATOM   5560 C CA    . LEU D 4 322 ? 125.246 115.843 168.593 1.00 68.98  ? 159 LEU R CA    1 
ATOM   5561 C C     . LEU D 4 322 ? 124.448 116.655 169.603 1.00 69.53  ? 159 LEU R C     1 
ATOM   5562 O O     . LEU D 4 322 ? 124.623 116.455 170.810 1.00 70.56  ? 159 LEU R O     1 
ATOM   5563 C CB    . LEU D 4 322 ? 126.742 116.109 168.777 1.00 67.35  ? 159 LEU R CB    1 
ATOM   5564 C CG    . LEU D 4 322 ? 127.660 115.119 168.056 1.00 70.32  ? 159 LEU R CG    1 
ATOM   5565 C CD1   . LEU D 4 322 ? 129.122 115.492 168.237 1.00 71.54  ? 159 LEU R CD1   1 
ATOM   5566 C CD2   . LEU D 4 322 ? 127.401 113.701 168.540 1.00 73.41  ? 159 LEU R CD2   1 
ATOM   5567 N N     . THR D 4 323 ? 123.585 117.563 169.149 1.00 72.96  ? 160 THR R N     1 
ATOM   5568 C CA    . THR D 4 323 ? 122.700 118.308 170.045 1.00 75.60  ? 160 THR R CA    1 
ATOM   5569 C C     . THR D 4 323 ? 121.398 117.523 170.222 1.00 82.81  ? 160 THR R C     1 
ATOM   5570 O O     . THR D 4 323 ? 120.309 117.941 169.823 1.00 83.77  ? 160 THR R O     1 
ATOM   5571 C CB    . THR D 4 323 ? 122.448 119.710 169.504 1.00 76.75  ? 160 THR R CB    1 
ATOM   5572 O OG1   . THR D 4 323 ? 123.673 120.256 169.001 1.00 78.61  ? 160 THR R OG1   1 
ATOM   5573 C CG2   . THR D 4 323 ? 121.915 120.618 170.603 1.00 79.82  ? 160 THR R CG2   1 
ATOM   5574 N N     . ASN D 4 324 ? 121.537 116.348 170.838 1.00 92.84  ? 161 ASN R N     1 
ATOM   5575 C CA    . ASN D 4 324 ? 120.429 115.419 170.997 1.00 90.99  ? 161 ASN R CA    1 
ATOM   5576 C C     . ASN D 4 324 ? 119.955 115.268 172.435 1.00 92.00  ? 161 ASN R C     1 
ATOM   5577 O O     . ASN D 4 324 ? 118.953 114.582 172.666 1.00 94.53  ? 161 ASN R O     1 
ATOM   5578 C CB    . ASN D 4 324 ? 120.815 114.036 170.449 1.00 87.81  ? 161 ASN R CB    1 
ATOM   5579 N N     . GLN D 4 325 ? 120.639 115.876 173.401 1.00 86.94  ? 162 GLN R N     1 
ATOM   5580 C CA    . GLN D 4 325 ? 120.228 115.759 174.793 1.00 87.44  ? 162 GLN R CA    1 
ATOM   5581 C C     . GLN D 4 325 ? 118.887 116.446 175.016 1.00 91.64  ? 162 GLN R C     1 
ATOM   5582 O O     . GLN D 4 325 ? 118.652 117.560 174.540 1.00 94.13  ? 162 GLN R O     1 
ATOM   5583 C CB    . GLN D 4 325 ? 121.288 116.365 175.712 1.00 86.62  ? 162 GLN R CB    1 
ATOM   5584 C CG    . GLN D 4 325 ? 122.608 115.614 175.719 1.00 87.29  ? 162 GLN R CG    1 
ATOM   5585 C CD    . GLN D 4 325 ? 122.568 114.376 176.593 1.00 90.69  ? 162 GLN R CD    1 
ATOM   5586 O OE1   . GLN D 4 325 ? 121.930 114.365 177.645 1.00 91.05  ? 162 GLN R OE1   1 
ATOM   5587 N NE2   . GLN D 4 325 ? 123.253 113.323 176.160 1.00 89.89  ? 162 GLN R NE2   1 
ATOM   5588 N N     . SER D 4 326 ? 118.002 115.770 175.743 1.00 93.22  ? 163 SER R N     1 
ATOM   5589 C CA    . SER D 4 326 ? 116.689 116.326 176.033 1.00 94.59  ? 163 SER R CA    1 
ATOM   5590 C C     . SER D 4 326 ? 116.796 117.454 177.053 1.00 95.10  ? 163 SER R C     1 
ATOM   5591 O O     . SER D 4 326 ? 117.656 117.446 177.938 1.00 92.80  ? 163 SER R O     1 
ATOM   5592 C CB    . SER D 4 326 ? 115.750 115.237 176.550 1.00 94.40  ? 163 SER R CB    1 
ATOM   5593 O OG    . SER D 4 326 ? 114.426 115.727 176.679 1.00 95.05  ? 163 SER R OG    1 
ATOM   5594 N N     . VAL D 4 327 ? 115.904 118.435 176.920 1.00 95.69  ? 164 VAL R N     1 
ATOM   5595 C CA    . VAL D 4 327 ? 115.905 119.578 177.824 1.00 95.61  ? 164 VAL R CA    1 
ATOM   5596 C C     . VAL D 4 327 ? 115.412 119.139 179.195 1.00 95.67  ? 164 VAL R C     1 
ATOM   5597 O O     . VAL D 4 327 ? 114.354 118.508 179.321 1.00 95.29  ? 164 VAL R O     1 
ATOM   5598 C CB    . VAL D 4 327 ? 115.041 120.714 177.258 1.00 93.81  ? 164 VAL R CB    1 
ATOM   5599 N N     . ARG D 4 328 ? 116.184 119.469 180.234 1.00 100.33 ? 165 ARG R N     1 
ATOM   5600 C CA    . ARG D 4 328 ? 115.784 119.119 181.593 1.00 102.73 ? 165 ARG R CA    1 
ATOM   5601 C C     . ARG D 4 328 ? 114.507 119.843 181.997 1.00 103.65 ? 165 ARG R C     1 
ATOM   5602 O O     . ARG D 4 328 ? 113.622 119.254 182.628 1.00 100.64 ? 165 ARG R O     1 
ATOM   5603 C CB    . ARG D 4 328 ? 116.915 119.437 182.571 1.00 100.91 ? 165 ARG R CB    1 
ATOM   5604 N N     . GLU D 4 329 ? 114.392 121.121 181.642 1.00 105.35 ? 166 GLU R N     1 
ATOM   5605 C CA    . GLU D 4 329 ? 113.210 121.911 181.947 1.00 103.01 ? 166 GLU R CA    1 
ATOM   5606 C C     . GLU D 4 329 ? 112.825 122.729 180.724 1.00 102.95 ? 166 GLU R C     1 
ATOM   5607 O O     . GLU D 4 329 ? 113.675 123.090 179.906 1.00 100.32 ? 166 GLU R O     1 
ATOM   5608 C CB    . GLU D 4 329 ? 113.443 122.837 183.149 1.00 102.11 ? 166 GLU R CB    1 
ATOM   5609 N N     . VAL D 4 330 ? 111.525 123.017 180.607 1.00 103.76 ? 167 VAL R N     1 
ATOM   5610 C CA    . VAL D 4 330 ? 111.020 123.801 179.483 1.00 101.89 ? 167 VAL R CA    1 
ATOM   5611 C C     . VAL D 4 330 ? 111.063 125.299 179.742 1.00 102.70 ? 167 VAL R C     1 
ATOM   5612 O O     . VAL D 4 330 ? 110.807 126.084 178.814 1.00 102.44 ? 167 VAL R O     1 
ATOM   5613 C CB    . VAL D 4 330 ? 109.576 123.393 179.128 1.00 98.87  ? 167 VAL R CB    1 
ATOM   5614 N N     . THR D 4 331 ? 111.370 125.725 180.970 1.00 99.95  ? 168 THR R N     1 
ATOM   5615 C CA    . THR D 4 331 ? 111.433 127.154 181.264 1.00 99.99  ? 168 THR R CA    1 
ATOM   5616 C C     . THR D 4 331 ? 112.555 127.830 180.486 1.00 99.65  ? 168 THR R C     1 
ATOM   5617 O O     . THR D 4 331 ? 112.372 128.926 179.943 1.00 98.13  ? 168 THR R O     1 
ATOM   5618 C CB    . THR D 4 331 ? 111.615 127.375 182.765 1.00 98.63  ? 168 THR R CB    1 
ATOM   5619 N N     . GLN D 4 332 ? 113.723 127.195 180.421 1.00 103.62 ? 169 GLN R N     1 
ATOM   5620 C CA    . GLN D 4 332 ? 114.855 127.742 179.690 1.00 103.35 ? 169 GLN R CA    1 
ATOM   5621 C C     . GLN D 4 332 ? 115.663 126.597 179.099 1.00 103.56 ? 169 GLN R C     1 
ATOM   5622 O O     . GLN D 4 332 ? 115.692 125.492 179.646 1.00 102.85 ? 169 GLN R O     1 
ATOM   5623 C CB    . GLN D 4 332 ? 115.742 128.612 180.589 1.00 103.73 ? 169 GLN R CB    1 
ATOM   5624 N N     . ILE D 4 333 ? 116.321 126.875 177.976 1.00 95.02  ? 170 ILE R N     1 
ATOM   5625 C CA    . ILE D 4 333 ? 117.136 125.893 177.273 1.00 94.77  ? 170 ILE R CA    1 
ATOM   5626 C C     . ILE D 4 333 ? 118.504 126.502 177.005 1.00 96.95  ? 170 ILE R C     1 
ATOM   5627 O O     . ILE D 4 333 ? 118.601 127.623 176.493 1.00 96.56  ? 170 ILE R O     1 
ATOM   5628 C CB    . ILE D 4 333 ? 116.479 125.441 175.955 1.00 92.95  ? 170 ILE R CB    1 
ATOM   5629 N N     . LYS D 4 334 ? 119.556 125.766 177.351 1.00 98.91  ? 171 LYS R N     1 
ATOM   5630 C CA    . LYS D 4 334 ? 120.929 126.177 177.098 1.00 96.81  ? 171 LYS R CA    1 
ATOM   5631 C C     . LYS D 4 334 ? 121.564 125.233 176.086 1.00 93.98  ? 171 LYS R C     1 
ATOM   5632 O O     . LYS D 4 334 ? 121.391 124.013 176.168 1.00 96.89  ? 171 LYS R O     1 
ATOM   5633 C CB    . LYS D 4 334 ? 121.751 126.189 178.389 1.00 97.01  ? 171 LYS R CB    1 
ATOM   5634 C CG    . LYS D 4 334 ? 121.288 127.212 179.414 1.00 95.37  ? 171 LYS R CG    1 
ATOM   5635 C CD    . LYS D 4 334 ? 122.183 127.199 180.642 1.00 96.01  ? 171 LYS R CD    1 
ATOM   5636 C CE    . LYS D 4 334 ? 121.730 128.223 181.668 1.00 98.50  ? 171 LYS R CE    1 
ATOM   5637 N NZ    . LYS D 4 334 ? 122.616 128.235 182.865 1.00 98.73  ? 171 LYS R NZ    1 
ATOM   5638 N N     . CYS D 4 335 ? 122.301 125.806 175.131 1.00 84.57  ? 172 CYS R N     1 
ATOM   5639 C CA    . CYS D 4 335 ? 122.920 124.995 174.087 1.00 89.79  ? 172 CYS R CA    1 
ATOM   5640 C C     . CYS D 4 335 ? 123.934 124.015 174.662 1.00 92.32  ? 172 CYS R C     1 
ATOM   5641 O O     . CYS D 4 335 ? 124.044 122.882 174.178 1.00 96.39  ? 172 CYS R O     1 
ATOM   5642 C CB    . CYS D 4 335 ? 123.584 125.895 173.046 1.00 88.59  ? 172 CYS R CB    1 
ATOM   5643 S SG    . CYS D 4 335 ? 122.436 126.613 171.853 1.00 101.90 ? 172 CYS R SG    1 
ATOM   5644 N N     . ILE D 4 336 ? 124.684 124.430 175.684 1.00 86.76  ? 173 ILE R N     1 
ATOM   5645 C CA    . ILE D 4 336 ? 125.651 123.532 176.306 1.00 87.44  ? 173 ILE R CA    1 
ATOM   5646 C C     . ILE D 4 336 ? 124.949 122.377 177.011 1.00 90.44  ? 173 ILE R C     1 
ATOM   5647 O O     . ILE D 4 336 ? 125.458 121.250 177.028 1.00 90.53  ? 173 ILE R O     1 
ATOM   5648 C CB    . ILE D 4 336 ? 126.561 124.319 177.267 1.00 85.78  ? 173 ILE R CB    1 
ATOM   5649 C CG1   . ILE D 4 336 ? 125.727 125.018 178.344 1.00 88.52  ? 173 ILE R CG1   1 
ATOM   5650 C CG2   . ILE D 4 336 ? 127.388 125.329 176.491 1.00 83.33  ? 173 ILE R CG2   1 
ATOM   5651 C CD1   . ILE D 4 336 ? 126.540 125.578 179.488 1.00 86.84  ? 173 ILE R CD1   1 
ATOM   5652 N N     . GLU D 4 337 ? 123.778 122.627 177.601 1.00 90.21  ? 174 GLU R N     1 
ATOM   5653 C CA    . GLU D 4 337 ? 123.034 121.585 178.294 1.00 90.27  ? 174 GLU R CA    1 
ATOM   5654 C C     . GLU D 4 337 ? 122.323 120.631 177.344 1.00 90.48  ? 174 GLU R C     1 
ATOM   5655 O O     . GLU D 4 337 ? 121.839 119.586 177.791 1.00 93.72  ? 174 GLU R O     1 
ATOM   5656 C CB    . GLU D 4 337 ? 122.014 122.213 179.247 1.00 88.72  ? 174 GLU R CB    1 
ATOM   5657 N N     . LEU D 4 338 ? 122.249 120.960 176.056 1.00 81.99  ? 175 LEU R N     1 
ATOM   5658 C CA    . LEU D 4 338 ? 121.603 120.114 175.064 1.00 84.15  ? 175 LEU R CA    1 
ATOM   5659 C C     . LEU D 4 338 ? 122.598 119.279 174.268 1.00 86.72  ? 175 LEU R C     1 
ATOM   5660 O O     . LEU D 4 338 ? 122.214 118.658 173.273 1.00 90.30  ? 175 LEU R O     1 
ATOM   5661 C CB    . LEU D 4 338 ? 120.759 120.967 174.115 1.00 84.72  ? 175 LEU R CB    1 
ATOM   5662 C CG    . LEU D 4 338 ? 119.604 121.742 174.751 1.00 86.46  ? 175 LEU R CG    1 
ATOM   5663 C CD1   . LEU D 4 338 ? 119.129 122.850 173.825 1.00 85.68  ? 175 LEU R CD1   1 
ATOM   5664 C CD2   . LEU D 4 338 ? 118.459 120.808 175.107 1.00 85.81  ? 175 LEU R CD2   1 
ATOM   5665 N N     . LYS D 4 339 ? 123.861 119.248 174.683 1.00 80.83  ? 176 LYS R N     1 
ATOM   5666 C CA    . LYS D 4 339 ? 124.898 118.500 173.990 1.00 82.48  ? 176 LYS R CA    1 
ATOM   5667 C C     . LYS D 4 339 ? 125.536 117.489 174.932 1.00 85.37  ? 176 LYS R C     1 
ATOM   5668 O O     . LYS D 4 339 ? 125.631 117.714 176.142 1.00 85.02  ? 176 LYS R O     1 
ATOM   5669 C CB    . LYS D 4 339 ? 125.981 119.432 173.430 1.00 81.26  ? 176 LYS R CB    1 
ATOM   5670 C CG    . LYS D 4 339 ? 125.515 120.324 172.295 1.00 80.97  ? 176 LYS R CG    1 
ATOM   5671 C CD    . LYS D 4 339 ? 126.604 121.303 171.891 1.00 79.74  ? 176 LYS R CD    1 
ATOM   5672 C CE    . LYS D 4 339 ? 126.075 122.346 170.924 1.00 79.56  ? 176 LYS R CE    1 
ATOM   5673 N NZ    . LYS D 4 339 ? 125.691 121.735 169.622 1.00 83.07  ? 176 LYS R NZ    1 
ATOM   5674 N N     . SER D 4 340 ? 125.973 116.370 174.361 1.00 87.25  ? 177 SER R N     1 
ATOM   5675 C CA    . SER D 4 340 ? 126.678 115.359 175.130 1.00 86.01  ? 177 SER R CA    1 
ATOM   5676 C C     . SER D 4 340 ? 128.103 115.822 175.428 1.00 83.30  ? 177 SER R C     1 
ATOM   5677 O O     . SER D 4 340 ? 128.559 116.868 174.957 1.00 83.59  ? 177 SER R O     1 
ATOM   5678 C CB    . SER D 4 340 ? 126.696 114.030 174.376 1.00 86.02  ? 177 SER R CB    1 
ATOM   5679 O OG    . SER D 4 340 ? 125.381 113.601 174.068 1.00 88.76  ? 177 SER R OG    1 
ATOM   5680 N N     . GLU D 4 341 ? 128.810 115.025 176.233 1.00 83.39  ? 178 GLU R N     1 
ATOM   5681 C CA    . GLU D 4 341 ? 130.194 115.351 176.563 1.00 85.10  ? 178 GLU R CA    1 
ATOM   5682 C C     . GLU D 4 341 ? 131.061 115.375 175.310 1.00 85.43  ? 178 GLU R C     1 
ATOM   5683 O O     . GLU D 4 341 ? 131.858 116.300 175.108 1.00 82.74  ? 178 GLU R O     1 
ATOM   5684 C CB    . GLU D 4 341 ? 130.740 114.349 177.581 1.00 82.30  ? 178 GLU R CB    1 
ATOM   5685 N N     . LEU D 4 342 ? 130.906 114.368 174.448 1.00 85.56  ? 179 LEU R N     1 
ATOM   5686 C CA    . LEU D 4 342 ? 131.616 114.377 173.174 1.00 85.17  ? 179 LEU R CA    1 
ATOM   5687 C C     . LEU D 4 342 ? 131.161 115.545 172.309 1.00 84.93  ? 179 LEU R C     1 
ATOM   5688 O O     . LEU D 4 342 ? 131.983 116.208 171.668 1.00 81.26  ? 179 LEU R O     1 
ATOM   5689 C CB    . LEU D 4 342 ? 131.411 113.048 172.445 1.00 85.95  ? 179 LEU R CB    1 
ATOM   5690 C CG    . LEU D 4 342 ? 132.294 112.753 171.227 1.00 88.02  ? 179 LEU R CG    1 
ATOM   5691 C CD1   . LEU D 4 342 ? 132.574 111.263 171.131 1.00 89.12  ? 179 LEU R CD1   1 
ATOM   5692 C CD2   . LEU D 4 342 ? 131.658 113.251 169.934 1.00 83.85  ? 179 LEU R CD2   1 
ATOM   5693 N N     . GLY D 4 343 ? 129.854 115.814 172.284 1.00 81.29  ? 180 GLY R N     1 
ATOM   5694 C CA    . GLY D 4 343 ? 129.358 116.950 171.524 1.00 80.98  ? 180 GLY R CA    1 
ATOM   5695 C C     . GLY D 4 343 ? 129.854 118.277 172.063 1.00 78.13  ? 180 GLY R C     1 
ATOM   5696 O O     . GLY D 4 343 ? 130.230 119.168 171.297 1.00 77.42  ? 180 GLY R O     1 
ATOM   5697 N N     . ARG D 4 344 ? 129.861 118.427 173.390 1.00 75.18  ? 181 ARG R N     1 
ATOM   5698 C CA    . ARG D 4 344 ? 130.367 119.657 173.991 1.00 71.29  ? 181 ARG R CA    1 
ATOM   5699 C C     . ARG D 4 344 ? 131.846 119.851 173.683 1.00 72.38  ? 181 ARG R C     1 
ATOM   5700 O O     . ARG D 4 344 ? 132.275 120.960 173.343 1.00 77.90  ? 181 ARG R O     1 
ATOM   5701 C CB    . ARG D 4 344 ? 130.129 119.643 175.501 1.00 68.87  ? 181 ARG R CB    1 
ATOM   5702 N N     . LYS D 4 345 ? 132.641 118.782 173.786 1.00 66.75  ? 182 LYS R N     1 
ATOM   5703 C CA    . LYS D 4 345 ? 134.062 118.888 173.469 1.00 68.24  ? 182 LYS R CA    1 
ATOM   5704 C C     . LYS D 4 345 ? 134.278 119.218 171.996 1.00 70.90  ? 182 LYS R C     1 
ATOM   5705 O O     . LYS D 4 345 ? 135.122 120.058 171.656 1.00 69.73  ? 182 LYS R O     1 
ATOM   5706 C CB    . LYS D 4 345 ? 134.780 117.591 173.839 1.00 67.72  ? 182 LYS R CB    1 
ATOM   5707 N N     . TRP D 4 346 ? 133.521 118.570 171.106 1.00 71.71  ? 183 TRP R N     1 
ATOM   5708 C CA    . TRP D 4 346 ? 133.678 118.833 169.682 1.00 66.50  ? 183 TRP R CA    1 
ATOM   5709 C C     . TRP D 4 346 ? 133.280 120.255 169.324 1.00 69.10  ? 183 TRP R C     1 
ATOM   5710 O O     . TRP D 4 346 ? 133.926 120.875 168.478 1.00 75.01  ? 183 TRP R O     1 
ATOM   5711 C CB    . TRP D 4 346 ? 132.865 117.840 168.855 1.00 67.60  ? 183 TRP R CB    1 
ATOM   5712 C CG    . TRP D 4 346 ? 132.992 118.089 167.383 1.00 68.70  ? 183 TRP R CG    1 
ATOM   5713 C CD1   . TRP D 4 346 ? 132.102 118.742 166.583 1.00 64.59  ? 183 TRP R CD1   1 
ATOM   5714 C CD2   . TRP D 4 346 ? 134.088 117.713 166.540 1.00 75.41  ? 183 TRP R CD2   1 
ATOM   5715 N NE1   . TRP D 4 346 ? 132.568 118.786 165.292 1.00 67.37  ? 183 TRP R NE1   1 
ATOM   5716 C CE2   . TRP D 4 346 ? 133.786 118.161 165.239 1.00 74.06  ? 183 TRP R CE2   1 
ATOM   5717 C CE3   . TRP D 4 346 ? 135.291 117.035 166.758 1.00 74.64  ? 183 TRP R CE3   1 
ATOM   5718 C CZ2   . TRP D 4 346 ? 134.643 117.953 164.160 1.00 72.40  ? 183 TRP R CZ2   1 
ATOM   5719 C CZ3   . TRP D 4 346 ? 136.141 116.830 165.686 1.00 75.15  ? 183 TRP R CZ3   1 
ATOM   5720 C CH2   . TRP D 4 346 ? 135.813 117.288 164.404 1.00 73.39  ? 183 TRP R CH2   1 
ATOM   5721 N N     . HIS D 4 347 ? 132.226 120.791 169.942 1.00 61.71  ? 184 HIS R N     1 
ATOM   5722 C CA    . HIS D 4 347 ? 131.881 122.184 169.680 1.00 60.63  ? 184 HIS R CA    1 
ATOM   5723 C C     . HIS D 4 347 ? 132.903 123.140 170.281 1.00 60.60  ? 184 HIS R C     1 
ATOM   5724 O O     . HIS D 4 347 ? 133.217 124.173 169.680 1.00 68.98  ? 184 HIS R O     1 
ATOM   5725 C CB    . HIS D 4 347 ? 130.480 122.509 170.186 1.00 63.47  ? 184 HIS R CB    1 
ATOM   5726 C CG    . HIS D 4 347 ? 130.236 123.977 170.335 1.00 64.99  ? 184 HIS R CG    1 
ATOM   5727 N ND1   . HIS D 4 347 ? 130.040 124.577 171.560 1.00 52.45  ? 184 HIS R ND1   1 
ATOM   5728 C CD2   . HIS D 4 347 ? 130.268 124.981 169.428 1.00 69.70  ? 184 HIS R CD2   1 
ATOM   5729 C CE1   . HIS D 4 347 ? 129.897 125.879 171.394 1.00 57.21  ? 184 HIS R CE1   1 
ATOM   5730 N NE2   . HIS D 4 347 ? 130.038 126.151 170.110 1.00 70.08  ? 184 HIS R NE2   1 
ATOM   5731 N N     . LYS D 4 348 ? 133.434 122.822 171.458 1.00 56.12  ? 185 LYS R N     1 
ATOM   5732 C CA    . LYS D 4 348 ? 134.469 123.680 172.023 1.00 58.15  ? 185 LYS R CA    1 
ATOM   5733 C C     . LYS D 4 348 ? 135.725 123.702 171.176 1.00 62.19  ? 185 LYS R C     1 
ATOM   5734 O O     . LYS D 4 348 ? 136.430 124.720 171.141 1.00 63.86  ? 185 LYS R O     1 
ATOM   5735 C CB    . LYS D 4 348 ? 134.794 123.228 173.448 1.00 62.39  ? 185 LYS R CB    1 
ATOM   5736 C CG    . LYS D 4 348 ? 135.703 124.171 174.217 1.00 60.48  ? 185 LYS R CG    1 
ATOM   5737 C CD    . LYS D 4 348 ? 136.055 123.600 175.580 1.00 64.75  ? 185 LYS R CD    1 
ATOM   5738 C CE    . LYS D 4 348 ? 136.976 124.529 176.351 1.00 64.11  ? 185 LYS R CE    1 
ATOM   5739 N NZ    . LYS D 4 348 ? 137.387 123.944 177.657 1.00 65.18  ? 185 LYS R NZ    1 
ATOM   5740 N N     . ALA D 4 349 ? 136.011 122.600 170.484 1.00 50.05  ? 186 ALA R N     1 
ATOM   5741 C CA    . ALA D 4 349 ? 137.097 122.567 169.511 1.00 50.75  ? 186 ALA R CA    1 
ATOM   5742 C C     . ALA D 4 349 ? 136.761 123.235 168.184 1.00 56.04  ? 186 ALA R C     1 
ATOM   5743 O O     . ALA D 4 349 ? 137.624 123.930 167.634 1.00 63.78  ? 186 ALA R O     1 
ATOM   5744 C CB    . ALA D 4 349 ? 137.531 121.120 169.236 1.00 59.16  ? 186 ALA R CB    1 
ATOM   5745 N N     . SER D 4 350 ? 135.548 123.065 167.659 1.00 49.70  ? 187 SER R N     1 
ATOM   5746 C CA    . SER D 4 350 ? 135.145 123.666 166.394 1.00 44.72  ? 187 SER R CA    1 
ATOM   5747 C C     . SER D 4 350 ? 135.029 125.180 166.487 1.00 47.99  ? 187 SER R C     1 
ATOM   5748 O O     . SER D 4 350 ? 135.380 125.883 165.535 1.00 55.17  ? 187 SER R O     1 
ATOM   5749 C CB    . SER D 4 350 ? 133.816 123.070 165.925 1.00 44.09  ? 187 SER R CB    1 
ATOM   5750 O OG    . SER D 4 350 ? 132.751 123.466 166.770 1.00 50.67  ? 187 SER R OG    1 
ATOM   5751 N N     . ASN D 4 351 ? 134.539 125.700 167.615 1.00 44.21  ? 188 ASN R N     1 
ATOM   5752 C CA    . ASN D 4 351 ? 134.504 127.143 167.805 1.00 44.22  ? 188 ASN R CA    1 
ATOM   5753 C C     . ASN D 4 351 ? 135.903 127.742 167.830 1.00 45.81  ? 188 ASN R C     1 
ATOM   5754 O O     . ASN D 4 351 ? 136.110 128.827 167.278 1.00 54.20  ? 188 ASN R O     1 
ATOM   5755 C CB    . ASN D 4 351 ? 133.764 127.486 169.098 1.00 39.64  ? 188 ASN R CB    1 
ATOM   5756 C CG    . ASN D 4 351 ? 133.644 128.979 169.321 1.00 46.96  ? 188 ASN R CG    1 
ATOM   5757 O OD1   . ASN D 4 351 ? 134.151 129.514 170.306 1.00 51.87  ? 188 ASN R OD1   1 
ATOM   5758 N ND2   . ASN D 4 351 ? 132.968 129.660 168.405 1.00 58.11  ? 188 ASN R ND2   1 
ATOM   5759 N N     . TYR D 4 352 ? 136.865 127.055 168.446 1.00 46.19  ? 189 TYR R N     1 
ATOM   5760 C CA    . TYR D 4 352 ? 138.259 127.474 168.403 1.00 47.96  ? 189 TYR R CA    1 
ATOM   5761 C C     . TYR D 4 352 ? 138.859 127.386 167.008 1.00 51.88  ? 189 TYR R C     1 
ATOM   5762 O O     . TYR D 4 352 ? 139.599 128.293 166.611 1.00 55.92  ? 189 TYR R O     1 
ATOM   5763 C CB    . TYR D 4 352 ? 139.108 126.624 169.359 1.00 51.23  ? 189 TYR R CB    1 
ATOM   5764 C CG    . TYR D 4 352 ? 138.784 126.795 170.829 1.00 56.47  ? 189 TYR R CG    1 
ATOM   5765 C CD1   . TYR D 4 352 ? 137.853 127.731 171.256 1.00 60.18  ? 189 TYR R CD1   1 
ATOM   5766 C CD2   . TYR D 4 352 ? 139.414 126.014 171.789 1.00 57.79  ? 189 TYR R CD2   1 
ATOM   5767 C CE1   . TYR D 4 352 ? 137.560 127.886 172.595 1.00 58.47  ? 189 TYR R CE1   1 
ATOM   5768 C CE2   . TYR D 4 352 ? 139.126 126.162 173.131 1.00 58.63  ? 189 TYR R CE2   1 
ATOM   5769 C CZ    . TYR D 4 352 ? 138.198 127.100 173.529 1.00 59.59  ? 189 TYR R CZ    1 
ATOM   5770 O OH    . TYR D 4 352 ? 137.907 127.253 174.864 1.00 65.00  ? 189 TYR R OH    1 
ATOM   5771 N N     . ILE D 4 353 ? 138.558 126.325 166.266 1.00 44.80  ? 190 ILE R N     1 
ATOM   5772 C CA    . ILE D 4 353 ? 139.016 126.196 164.885 1.00 44.10  ? 190 ILE R CA    1 
ATOM   5773 C C     . ILE D 4 353 ? 138.472 127.322 164.019 1.00 46.13  ? 190 ILE R C     1 
ATOM   5774 O O     . ILE D 4 353 ? 139.190 127.880 163.186 1.00 53.64  ? 190 ILE R O     1 
ATOM   5775 C CB    . ILE D 4 353 ? 138.625 124.812 164.321 1.00 41.66  ? 190 ILE R CB    1 
ATOM   5776 C CG1   . ILE D 4 353 ? 139.404 123.703 165.030 1.00 47.03  ? 190 ILE R CG1   1 
ATOM   5777 C CG2   . ILE D 4 353 ? 138.871 124.752 162.822 1.00 45.96  ? 190 ILE R CG2   1 
ATOM   5778 C CD1   . ILE D 4 353 ? 138.890 122.313 164.728 1.00 45.84  ? 190 ILE R CD1   1 
ATOM   5779 N N     . PHE D 4 354 ? 137.199 127.674 164.205 1.00 37.51  ? 191 PHE R N     1 
ATOM   5780 C CA    . PHE D 4 354 ? 136.597 128.765 163.447 1.00 28.31  ? 191 PHE R CA    1 
ATOM   5781 C C     . PHE D 4 354 ? 137.289 130.091 163.744 1.00 34.72  ? 191 PHE R C     1 
ATOM   5782 O O     . PHE D 4 354 ? 137.566 130.881 162.836 1.00 44.38  ? 191 PHE R O     1 
ATOM   5783 C CB    . PHE D 4 354 ? 135.103 128.853 163.763 1.00 29.68  ? 191 PHE R CB    1 
ATOM   5784 C CG    . PHE D 4 354 ? 134.263 127.867 163.006 1.00 34.22  ? 191 PHE R CG    1 
ATOM   5785 C CD1   . PHE D 4 354 ? 134.581 127.520 161.705 1.00 41.05  ? 191 PHE R CD1   1 
ATOM   5786 C CD2   . PHE D 4 354 ? 133.150 127.292 163.593 1.00 31.08  ? 191 PHE R CD2   1 
ATOM   5787 C CE1   . PHE D 4 354 ? 133.807 126.615 161.007 1.00 38.43  ? 191 PHE R CE1   1 
ATOM   5788 C CE2   . PHE D 4 354 ? 132.372 126.387 162.899 1.00 31.50  ? 191 PHE R CE2   1 
ATOM   5789 C CZ    . PHE D 4 354 ? 132.701 126.049 161.604 1.00 33.35  ? 191 PHE R CZ    1 
ATOM   5790 N N     . VAL D 4 355 ? 137.578 130.350 165.021 1.00 24.05  ? 192 VAL R N     1 
ATOM   5791 C CA    . VAL D 4 355 ? 138.235 131.600 165.400 1.00 23.01  ? 192 VAL R CA    1 
ATOM   5792 C C     . VAL D 4 355 ? 139.652 131.648 164.839 1.00 33.08  ? 192 VAL R C     1 
ATOM   5793 O O     . VAL D 4 355 ? 140.112 132.685 164.346 1.00 39.51  ? 192 VAL R O     1 
ATOM   5794 C CB    . VAL D 4 355 ? 138.221 131.772 166.930 1.00 36.29  ? 192 VAL R CB    1 
ATOM   5795 C CG1   . VAL D 4 355 ? 139.040 132.982 167.339 1.00 40.02  ? 192 VAL R CG1   1 
ATOM   5796 C CG2   . VAL D 4 355 ? 136.793 131.919 167.426 1.00 27.94  ? 192 VAL R CG2   1 
ATOM   5797 N N     . ALA D 4 356 ? 140.367 130.521 164.907 1.00 22.97  ? 193 ALA R N     1 
ATOM   5798 C CA    . ALA D 4 356 ? 141.714 130.466 164.345 1.00 21.70  ? 193 ALA R CA    1 
ATOM   5799 C C     . ALA D 4 356 ? 141.694 130.683 162.837 1.00 32.02  ? 193 ALA R C     1 
ATOM   5800 O O     . ALA D 4 356 ? 142.544 131.398 162.290 1.00 27.83  ? 193 ALA R O     1 
ATOM   5801 C CB    . ALA D 4 356 ? 142.368 129.127 164.686 1.00 26.60  ? 193 ALA R CB    1 
ATOM   5802 N N     . ILE D 4 357 ? 140.728 130.071 162.148 1.00 32.58  ? 194 ILE R N     1 
ATOM   5803 C CA    . ILE D 4 357 ? 140.593 130.257 160.708 1.00 27.37  ? 194 ILE R CA    1 
ATOM   5804 C C     . ILE D 4 357 ? 140.302 131.715 160.390 1.00 32.04  ? 194 ILE R C     1 
ATOM   5805 O O     . ILE D 4 357 ? 140.878 132.291 159.458 1.00 37.94  ? 194 ILE R O     1 
ATOM   5806 C CB    . ILE D 4 357 ? 139.500 129.323 160.153 1.00 26.42  ? 194 ILE R CB    1 
ATOM   5807 C CG1   . ILE D 4 357 ? 140.070 127.928 159.893 1.00 41.14  ? 194 ILE R CG1   1 
ATOM   5808 C CG2   . ILE D 4 357 ? 138.887 129.897 158.883 1.00 30.30  ? 194 ILE R CG2   1 
ATOM   5809 C CD1   . ILE D 4 357 ? 139.013 126.875 159.645 1.00 38.60  ? 194 ILE R CD1   1 
ATOM   5810 N N     . PHE D 4 358 ? 139.413 132.340 161.167 1.00 24.46  ? 195 PHE R N     1 
ATOM   5811 C CA    . PHE D 4 358 ? 139.116 133.749 160.946 1.00 16.58  ? 195 PHE R CA    1 
ATOM   5812 C C     . PHE D 4 358 ? 140.350 134.611 161.149 1.00 25.74  ? 195 PHE R C     1 
ATOM   5813 O O     . PHE D 4 358 ? 140.568 135.568 160.405 1.00 34.60  ? 195 PHE R O     1 
ATOM   5814 C CB    . PHE D 4 358 ? 138.007 134.235 161.874 1.00 21.98  ? 195 PHE R CB    1 
ATOM   5815 C CG    . PHE D 4 358 ? 137.959 135.733 161.996 1.00 22.02  ? 195 PHE R CG    1 
ATOM   5816 C CD1   . PHE D 4 358 ? 137.315 136.492 161.038 1.00 32.98  ? 195 PHE R CD1   1 
ATOM   5817 C CD2   . PHE D 4 358 ? 138.595 136.384 163.042 1.00 29.64  ? 195 PHE R CD2   1 
ATOM   5818 C CE1   . PHE D 4 358 ? 137.285 137.865 161.131 1.00 35.67  ? 195 PHE R CE1   1 
ATOM   5819 C CE2   . PHE D 4 358 ? 138.566 137.760 163.139 1.00 34.92  ? 195 PHE R CE2   1 
ATOM   5820 C CZ    . PHE D 4 358 ? 137.910 138.501 162.184 1.00 29.73  ? 195 PHE R CZ    1 
ATOM   5821 N N     . TRP D 4 359 ? 141.145 134.320 162.179 1.00 29.09  ? 196 TRP R N     1 
ATOM   5822 C CA    . TRP D 4 359 ? 142.319 135.147 162.440 1.00 28.04  ? 196 TRP R CA    1 
ATOM   5823 C C     . TRP D 4 359 ? 143.368 134.975 161.350 1.00 33.23  ? 196 TRP R C     1 
ATOM   5824 O O     . TRP D 4 359 ? 144.024 135.946 160.953 1.00 33.41  ? 196 TRP R O     1 
ATOM   5825 C CB    . TRP D 4 359 ? 142.896 134.827 163.816 1.00 27.77  ? 196 TRP R CB    1 
ATOM   5826 C CG    . TRP D 4 359 ? 142.155 135.508 164.924 1.00 37.43  ? 196 TRP R CG    1 
ATOM   5827 C CD1   . TRP D 4 359 ? 141.494 134.912 165.954 1.00 37.49  ? 196 TRP R CD1   1 
ATOM   5828 C CD2   . TRP D 4 359 ? 141.987 136.920 165.103 1.00 25.64  ? 196 TRP R CD2   1 
ATOM   5829 N NE1   . TRP D 4 359 ? 140.928 135.862 166.768 1.00 23.18  ? 196 TRP R NE1   1 
ATOM   5830 C CE2   . TRP D 4 359 ? 141.217 137.104 166.267 1.00 21.48  ? 196 TRP R CE2   1 
ATOM   5831 C CE3   . TRP D 4 359 ? 142.416 138.047 164.395 1.00 32.18  ? 196 TRP R CE3   1 
ATOM   5832 C CZ2   . TRP D 4 359 ? 140.866 138.365 166.739 1.00 25.10  ? 196 TRP R CZ2   1 
ATOM   5833 C CZ3   . TRP D 4 359 ? 142.066 139.299 164.865 1.00 35.16  ? 196 TRP R CZ3   1 
ATOM   5834 C CH2   . TRP D 4 359 ? 141.299 139.448 166.025 1.00 32.90  ? 196 TRP R CH2   1 
ATOM   5835 N N     . ILE D 4 360 ? 143.532 133.751 160.844 1.00 35.44  ? 197 ILE R N     1 
ATOM   5836 C CA    . ILE D 4 360 ? 144.429 133.534 159.712 1.00 25.70  ? 197 ILE R CA    1 
ATOM   5837 C C     . ILE D 4 360 ? 143.946 134.321 158.500 1.00 27.56  ? 197 ILE R C     1 
ATOM   5838 O O     . ILE D 4 360 ? 144.731 134.992 157.814 1.00 41.31  ? 197 ILE R O     1 
ATOM   5839 C CB    . ILE D 4 360 ? 144.546 132.031 159.400 1.00 28.95  ? 197 ILE R CB    1 
ATOM   5840 C CG1   . ILE D 4 360 ? 145.254 131.301 160.544 1.00 33.94  ? 197 ILE R CG1   1 
ATOM   5841 C CG2   . ILE D 4 360 ? 145.283 131.812 158.089 1.00 33.92  ? 197 ILE R CG2   1 
ATOM   5842 C CD1   . ILE D 4 360 ? 146.682 131.748 160.763 1.00 46.15  ? 197 ILE R CD1   1 
ATOM   5843 N N     . VAL D 4 361 ? 142.638 134.266 158.230 1.00 28.99  ? 198 VAL R N     1 
ATOM   5844 C CA    . VAL D 4 361 ? 142.074 134.986 157.092 1.00 31.47  ? 198 VAL R CA    1 
ATOM   5845 C C     . VAL D 4 361 ? 142.232 136.490 157.279 1.00 31.96  ? 198 VAL R C     1 
ATOM   5846 O O     . VAL D 4 361 ? 142.506 137.221 156.324 1.00 34.58  ? 198 VAL R O     1 
ATOM   5847 C CB    . VAL D 4 361 ? 140.600 134.587 156.888 1.00 27.32  ? 198 VAL R CB    1 
ATOM   5848 C CG1   . VAL D 4 361 ? 139.903 135.554 155.944 1.00 16.85  ? 198 VAL R CG1   1 
ATOM   5849 C CG2   . VAL D 4 361 ? 140.506 133.166 156.358 1.00 34.60  ? 198 VAL R CG2   1 
ATOM   5850 N N     . PHE D 4 362 ? 142.068 136.972 158.510 1.00 21.24  ? 199 PHE R N     1 
ATOM   5851 C CA    . PHE D 4 362 ? 142.199 138.397 158.792 1.00 22.69  ? 199 PHE R CA    1 
ATOM   5852 C C     . PHE D 4 362 ? 143.630 138.872 158.589 1.00 25.76  ? 199 PHE R C     1 
ATOM   5853 O O     . PHE D 4 362 ? 143.859 139.932 157.995 1.00 34.77  ? 199 PHE R O     1 
ATOM   5854 C CB    . PHE D 4 362 ? 141.725 138.684 160.218 1.00 35.24  ? 199 PHE R CB    1 
ATOM   5855 C CG    . PHE D 4 362 ? 142.068 140.061 160.714 1.00 32.11  ? 199 PHE R CG    1 
ATOM   5856 C CD1   . PHE D 4 362 ? 141.280 141.149 160.379 1.00 36.50  ? 199 PHE R CD1   1 
ATOM   5857 C CD2   . PHE D 4 362 ? 143.165 140.263 161.536 1.00 28.26  ? 199 PHE R CD2   1 
ATOM   5858 C CE1   . PHE D 4 362 ? 141.589 142.415 160.840 1.00 35.51  ? 199 PHE R CE1   1 
ATOM   5859 C CE2   . PHE D 4 362 ? 143.479 141.525 161.999 1.00 36.44  ? 199 PHE R CE2   1 
ATOM   5860 C CZ    . PHE D 4 362 ? 142.690 142.602 161.651 1.00 38.22  ? 199 PHE R CZ    1 
ATOM   5861 N N     . LEU D 4 363 ? 144.607 138.103 159.076 1.00 31.53  ? 200 LEU R N     1 
ATOM   5862 C CA    . LEU D 4 363 ? 146.004 138.465 158.855 1.00 27.93  ? 200 LEU R CA    1 
ATOM   5863 C C     . LEU D 4 363 ? 146.342 138.459 157.370 1.00 31.94  ? 200 LEU R C     1 
ATOM   5864 O O     . LEU D 4 363 ? 147.002 139.381 156.870 1.00 33.54  ? 200 LEU R O     1 
ATOM   5865 C CB    . LEU D 4 363 ? 146.921 137.511 159.620 1.00 23.13  ? 200 LEU R CB    1 
ATOM   5866 N N     . LEU D 4 364 ? 145.883 137.435 156.643 1.00 27.32  ? 201 LEU R N     1 
ATOM   5867 C CA    . LEU D 4 364 ? 146.134 137.381 155.207 1.00 33.27  ? 201 LEU R CA    1 
ATOM   5868 C C     . LEU D 4 364 ? 145.483 138.555 154.487 1.00 36.32  ? 201 LEU R C     1 
ATOM   5869 O O     . LEU D 4 364 ? 146.088 139.156 153.595 1.00 44.89  ? 201 LEU R O     1 
ATOM   5870 C CB    . LEU D 4 364 ? 145.631 136.055 154.637 1.00 31.40  ? 201 LEU R CB    1 
ATOM   5871 C CG    . LEU D 4 364 ? 146.431 134.809 155.014 1.00 37.35  ? 201 LEU R CG    1 
ATOM   5872 C CD1   . LEU D 4 364 ? 145.661 133.550 154.652 1.00 40.95  ? 201 LEU R CD1   1 
ATOM   5873 C CD2   . LEU D 4 364 ? 147.793 134.821 154.339 1.00 39.24  ? 201 LEU R CD2   1 
ATOM   5874 N N     . LEU D 4 365 ? 144.249 138.893 154.864 1.00 27.17  ? 202 LEU R N     1 
ATOM   5875 C CA    . LEU D 4 365 ? 143.543 140.007 154.241 1.00 27.30  ? 202 LEU R CA    1 
ATOM   5876 C C     . LEU D 4 365 ? 144.261 141.324 154.497 1.00 27.88  ? 202 LEU R C     1 
ATOM   5877 O O     . LEU D 4 365 ? 144.423 142.138 153.580 1.00 39.63  ? 202 LEU R O     1 
ATOM   5878 C CB    . LEU D 4 365 ? 142.107 140.059 154.767 1.00 31.61  ? 202 LEU R CB    1 
ATOM   5879 C CG    . LEU D 4 365 ? 141.143 141.120 154.237 1.00 33.50  ? 202 LEU R CG    1 
ATOM   5880 C CD1   . LEU D 4 365 ? 139.779 140.507 153.975 1.00 30.59  ? 202 LEU R CD1   1 
ATOM   5881 C CD2   . LEU D 4 365 ? 141.026 142.276 155.216 1.00 36.03  ? 202 LEU R CD2   1 
ATOM   5882 N N     . ILE D 4 366 ? 144.706 141.546 155.735 1.00 27.91  ? 203 ILE R N     1 
ATOM   5883 C CA    . ILE D 4 366 ? 145.418 142.778 156.061 1.00 29.02  ? 203 ILE R CA    1 
ATOM   5884 C C     . ILE D 4 366 ? 146.711 142.869 155.260 1.00 34.34  ? 203 ILE R C     1 
ATOM   5885 O O     . ILE D 4 366 ? 147.026 143.913 154.675 1.00 36.15  ? 203 ILE R O     1 
ATOM   5886 C CB    . ILE D 4 366 ? 145.684 142.863 157.574 1.00 32.88  ? 203 ILE R CB    1 
ATOM   5887 C CG1   . ILE D 4 366 ? 144.375 143.083 158.334 1.00 40.25  ? 203 ILE R CG1   1 
ATOM   5888 C CG2   . ILE D 4 366 ? 146.671 143.978 157.884 1.00 36.90  ? 203 ILE R CG2   1 
ATOM   5889 C CD1   . ILE D 4 366 ? 143.723 144.417 158.056 1.00 39.06  ? 203 ILE R CD1   1 
ATOM   5890 N N     . VAL D 4 367 ? 147.468 141.770 155.204 1.00 30.26  ? 204 VAL R N     1 
ATOM   5891 C CA    . VAL D 4 367 ? 148.736 141.779 154.476 1.00 29.30  ? 204 VAL R CA    1 
ATOM   5892 C C     . VAL D 4 367 ? 148.498 142.046 152.993 1.00 38.89  ? 204 VAL R C     1 
ATOM   5893 O O     . VAL D 4 367 ? 149.169 142.886 152.377 1.00 49.55  ? 204 VAL R O     1 
ATOM   5894 C CB    . VAL D 4 367 ? 149.489 140.455 154.697 1.00 27.87  ? 204 VAL R CB    1 
ATOM   5895 C CG1   . VAL D 4 367 ? 150.592 140.288 153.663 1.00 28.63  ? 204 VAL R CG1   1 
ATOM   5896 C CG2   . VAL D 4 367 ? 150.059 140.400 156.105 1.00 34.33  ? 204 VAL R CG2   1 
ATOM   5897 N N     . PHE D 4 368 ? 147.527 141.344 152.404 1.00 27.75  ? 205 PHE R N     1 
ATOM   5898 C CA    . PHE D 4 368 ? 147.269 141.485 150.976 1.00 29.07  ? 205 PHE R CA    1 
ATOM   5899 C C     . PHE D 4 368 ? 146.784 142.886 150.634 1.00 30.46  ? 205 PHE R C     1 
ATOM   5900 O O     . PHE D 4 368 ? 147.202 143.463 149.625 1.00 33.04  ? 205 PHE R O     1 
ATOM   5901 C CB    . PHE D 4 368 ? 146.253 140.437 150.521 1.00 26.64  ? 205 PHE R CB    1 
ATOM   5902 C CG    . PHE D 4 368 ? 146.761 139.026 150.600 1.00 39.47  ? 205 PHE R CG    1 
ATOM   5903 C CD1   . PHE D 4 368 ? 148.117 138.758 150.517 1.00 42.40  ? 205 PHE R CD1   1 
ATOM   5904 C CD2   . PHE D 4 368 ? 145.884 137.966 150.757 1.00 34.85  ? 205 PHE R CD2   1 
ATOM   5905 C CE1   . PHE D 4 368 ? 148.588 137.462 150.591 1.00 40.95  ? 205 PHE R CE1   1 
ATOM   5906 C CE2   . PHE D 4 368 ? 146.349 136.668 150.832 1.00 32.48  ? 205 PHE R CE2   1 
ATOM   5907 C CZ    . PHE D 4 368 ? 147.703 136.416 150.748 1.00 32.91  ? 205 PHE R CZ    1 
ATOM   5908 N N     . TYR D 4 369 ? 145.911 143.460 151.465 1.00 23.05  ? 206 TYR R N     1 
ATOM   5909 C CA    . TYR D 4 369 ? 145.401 144.791 151.161 1.00 24.51  ? 206 TYR R CA    1 
ATOM   5910 C C     . TYR D 4 369 ? 146.453 145.867 151.396 1.00 27.85  ? 206 TYR R C     1 
ATOM   5911 O O     . TYR D 4 369 ? 146.485 146.862 150.664 1.00 31.37  ? 206 TYR R O     1 
ATOM   5912 C CB    . TYR D 4 369 ? 144.137 145.067 151.970 1.00 25.12  ? 206 TYR R CB    1 
ATOM   5913 C CG    . TYR D 4 369 ? 142.891 144.545 151.291 1.00 26.46  ? 206 TYR R CG    1 
ATOM   5914 C CD1   . TYR D 4 369 ? 142.579 144.921 149.992 1.00 22.21  ? 206 TYR R CD1   1 
ATOM   5915 C CD2   . TYR D 4 369 ? 142.038 143.665 151.940 1.00 19.33  ? 206 TYR R CD2   1 
ATOM   5916 C CE1   . TYR D 4 369 ? 141.448 144.444 149.362 1.00 22.42  ? 206 TYR R CE1   1 
ATOM   5917 C CE2   . TYR D 4 369 ? 140.904 143.181 151.317 1.00 23.24  ? 206 TYR R CE2   1 
ATOM   5918 C CZ    . TYR D 4 369 ? 140.614 143.574 150.028 1.00 28.46  ? 206 TYR R CZ    1 
ATOM   5919 O OH    . TYR D 4 369 ? 139.486 143.097 149.403 1.00 38.78  ? 206 TYR R OH    1 
ATOM   5920 N N     . THR D 4 370 ? 147.331 145.689 152.388 1.00 27.68  ? 207 THR R N     1 
ATOM   5921 C CA    . THR D 4 370 ? 148.449 146.615 152.536 1.00 23.68  ? 207 THR R CA    1 
ATOM   5922 C C     . THR D 4 370 ? 149.370 146.552 151.325 1.00 35.47  ? 207 THR R C     1 
ATOM   5923 O O     . THR D 4 370 ? 149.833 147.588 150.831 1.00 48.26  ? 207 THR R O     1 
ATOM   5924 C CB    . THR D 4 370 ? 149.228 146.312 153.816 1.00 39.27  ? 207 THR R CB    1 
ATOM   5925 O OG1   . THR D 4 370 ? 149.458 144.902 153.916 1.00 47.93  ? 207 THR R OG1   1 
ATOM   5926 C CG2   . THR D 4 370 ? 148.454 146.788 155.037 1.00 40.24  ? 207 THR R CG2   1 
ATOM   5927 N N     . ALA D 4 371 ? 149.638 145.343 150.824 1.00 39.94  ? 208 ALA R N     1 
ATOM   5928 C CA    . ALA D 4 371 ? 150.454 145.208 149.621 1.00 36.47  ? 208 ALA R CA    1 
ATOM   5929 C C     . ALA D 4 371 ? 149.779 145.857 148.419 1.00 44.99  ? 208 ALA R C     1 
ATOM   5930 O O     . ALA D 4 371 ? 150.441 146.505 147.600 1.00 47.79  ? 208 ALA R O     1 
ATOM   5931 C CB    . ALA D 4 371 ? 150.743 143.734 149.346 1.00 24.17  ? 208 ALA R CB    1 
ATOM   5932 N N     . ILE D 4 372 ? 148.460 145.691 148.294 1.00 33.62  ? 209 ILE R N     1 
ATOM   5933 C CA    . ILE D 4 372 ? 147.728 146.295 147.183 1.00 28.72  ? 209 ILE R CA    1 
ATOM   5934 C C     . ILE D 4 372 ? 147.786 147.816 147.266 1.00 37.63  ? 209 ILE R C     1 
ATOM   5935 O O     . ILE D 4 372 ? 147.981 148.500 146.254 1.00 44.60  ? 209 ILE R O     1 
ATOM   5936 C CB    . ILE D 4 372 ? 146.276 145.781 147.158 1.00 27.99  ? 209 ILE R CB    1 
ATOM   5937 C CG1   . ILE D 4 372 ? 146.234 144.317 146.717 1.00 35.94  ? 209 ILE R CG1   1 
ATOM   5938 C CG2   . ILE D 4 372 ? 145.422 146.624 146.230 1.00 24.51  ? 209 ILE R CG2   1 
ATOM   5939 C CD1   . ILE D 4 372 ? 144.972 143.595 147.131 1.00 29.66  ? 209 ILE R CD1   1 
ATOM   5940 N N     . THR D 4 373 ? 147.611 148.371 148.469 1.00 36.64  ? 210 THR R N     1 
ATOM   5941 C CA    . THR D 4 373 ? 147.700 149.819 148.634 1.00 38.10  ? 210 THR R CA    1 
ATOM   5942 C C     . THR D 4 373 ? 149.098 150.328 148.306 1.00 37.67  ? 210 THR R C     1 
ATOM   5943 O O     . THR D 4 373 ? 149.251 151.382 147.676 1.00 44.72  ? 210 THR R O     1 
ATOM   5944 C CB    . THR D 4 373 ? 147.311 150.220 150.057 1.00 41.00  ? 210 THR R CB    1 
ATOM   5945 O OG1   . THR D 4 373 ? 148.038 149.420 150.997 1.00 50.03  ? 210 THR R OG1   1 
ATOM   5946 C CG2   . THR D 4 373 ? 145.822 150.030 150.277 1.00 37.98  ? 210 THR R CG2   1 
ATOM   5947 N N     . LYS D 4 374 ? 150.132 149.600 148.735 1.00 33.44  ? 211 LYS R N     1 
ATOM   5948 C CA    . LYS D 4 374 ? 151.497 150.000 148.409 1.00 37.42  ? 211 LYS R CA    1 
ATOM   5949 C C     . LYS D 4 374 ? 151.738 149.959 146.905 1.00 49.19  ? 211 LYS R C     1 
ATOM   5950 O O     . LYS D 4 374 ? 152.401 150.844 146.350 1.00 58.28  ? 211 LYS R O     1 
ATOM   5951 C CB    . LYS D 4 374 ? 152.496 149.105 149.141 1.00 40.52  ? 211 LYS R CB    1 
ATOM   5952 C CG    . LYS D 4 374 ? 152.711 149.483 150.598 1.00 46.41  ? 211 LYS R CG    1 
ATOM   5953 C CD    . LYS D 4 374 ? 153.786 148.625 151.243 1.00 47.25  ? 211 LYS R CD    1 
ATOM   5954 C CE    . LYS D 4 374 ? 153.333 147.181 151.378 1.00 49.98  ? 211 LYS R CE    1 
ATOM   5955 N NZ    . LYS D 4 374 ? 154.311 146.362 152.146 1.00 45.45  ? 211 LYS R NZ    1 
ATOM   5956 N N     . LYS D 4 375 ? 151.212 148.935 146.230 1.00 40.90  ? 212 LYS R N     1 
ATOM   5957 C CA    . LYS D 4 375 ? 151.338 148.855 144.778 1.00 39.61  ? 212 LYS R CA    1 
ATOM   5958 C C     . LYS D 4 375 ? 150.623 150.016 144.097 1.00 37.19  ? 212 LYS R C     1 
ATOM   5959 O O     . LYS D 4 375 ? 151.139 150.594 143.133 1.00 44.11  ? 212 LYS R O     1 
ATOM   5960 C CB    . LYS D 4 375 ? 150.786 147.518 144.281 1.00 40.75  ? 212 LYS R CB    1 
ATOM   5961 C CG    . LYS D 4 375 ? 150.825 147.340 142.772 1.00 36.64  ? 212 LYS R CG    1 
ATOM   5962 C CD    . LYS D 4 375 ? 152.251 147.236 142.262 1.00 43.18  ? 212 LYS R CD    1 
ATOM   5963 C CE    . LYS D 4 375 ? 152.289 147.177 140.744 1.00 46.65  ? 212 LYS R CE    1 
ATOM   5964 N NZ    . LYS D 4 375 ? 151.871 145.845 140.228 1.00 43.31  ? 212 LYS R NZ    1 
ATOM   5965 N N     . ILE D 4 376 ? 149.432 150.369 144.584 1.00 41.24  ? 213 ILE R N     1 
ATOM   5966 C CA    . ILE D 4 376 ? 148.674 151.468 143.991 1.00 39.62  ? 213 ILE R CA    1 
ATOM   5967 C C     . ILE D 4 376 ? 149.399 152.794 144.191 1.00 41.72  ? 213 ILE R C     1 
ATOM   5968 O O     . ILE D 4 376 ? 149.453 153.630 143.281 1.00 47.62  ? 213 ILE R O     1 
ATOM   5969 C CB    . ILE D 4 376 ? 147.249 151.507 144.574 1.00 39.46  ? 213 ILE R CB    1 
ATOM   5970 C CG1   . ILE D 4 376 ? 146.422 150.339 144.038 1.00 36.00  ? 213 ILE R CG1   1 
ATOM   5971 C CG2   . ILE D 4 376 ? 146.566 152.827 144.252 1.00 43.37  ? 213 ILE R CG2   1 
ATOM   5972 C CD1   . ILE D 4 376 ? 145.215 150.023 144.882 1.00 39.52  ? 213 ILE R CD1   1 
ATOM   5973 N N     . PHE D 4 377 ? 149.963 153.010 145.382 1.00 42.56  ? 214 PHE R N     1 
ATOM   5974 C CA    . PHE D 4 377 ? 150.653 154.268 145.654 1.00 50.61  ? 214 PHE R CA    1 
ATOM   5975 C C     . PHE D 4 377 ? 151.863 154.444 144.744 1.00 57.94  ? 214 PHE R C     1 
ATOM   5976 O O     . PHE D 4 377 ? 152.138 155.554 144.274 1.00 56.95  ? 214 PHE R O     1 
ATOM   5977 C CB    . PHE D 4 377 ? 151.065 154.332 147.124 1.00 51.99  ? 214 PHE R CB    1 
ATOM   5978 C CG    . PHE D 4 377 ? 149.909 154.487 148.072 1.00 56.74  ? 214 PHE R CG    1 
ATOM   5979 C CD1   . PHE D 4 377 ? 148.672 154.909 147.613 1.00 50.16  ? 214 PHE R CD1   1 
ATOM   5980 C CD2   . PHE D 4 377 ? 150.060 154.213 149.420 1.00 53.87  ? 214 PHE R CD2   1 
ATOM   5981 C CE1   . PHE D 4 377 ? 147.607 155.052 148.481 1.00 51.40  ? 214 PHE R CE1   1 
ATOM   5982 C CE2   . PHE D 4 377 ? 148.998 154.355 150.294 1.00 51.72  ? 214 PHE R CE2   1 
ATOM   5983 C CZ    . PHE D 4 377 ? 147.770 154.776 149.823 1.00 54.92  ? 214 PHE R CZ    1 
ATOM   5984 N N     . LYS D 4 378 ? 152.596 153.364 144.485 1.00 60.61  ? 215 LYS R N     1 
ATOM   5985 C CA    . LYS D 4 378 ? 153.721 153.403 143.560 1.00 62.37  ? 215 LYS R CA    1 
ATOM   5986 C C     . LYS D 4 378 ? 153.300 153.204 142.110 1.00 63.00  ? 215 LYS R C     1 
ATOM   5987 O O     . LYS D 4 378 ? 154.161 153.226 141.224 1.00 68.43  ? 215 LYS R O     1 
ATOM   5988 C CB    . LYS D 4 378 ? 154.756 152.342 143.946 1.00 55.67  ? 215 LYS R CB    1 
ATOM   5989 N N     . SER D 4 379 ? 152.006 153.012 141.848 1.00 60.44  ? 216 SER R N     1 
ATOM   5990 C CA    . SER D 4 379 ? 151.544 152.759 140.487 1.00 63.31  ? 216 SER R CA    1 
ATOM   5991 C C     . SER D 4 379 ? 151.602 154.020 139.634 1.00 61.51  ? 216 SER R C     1 
ATOM   5992 O O     . SER D 4 379 ? 152.309 154.070 138.621 1.00 64.62  ? 216 SER R O     1 
ATOM   5993 C CB    . SER D 4 379 ? 150.120 152.203 140.517 1.00 69.48  ? 216 SER R CB    1 
ATOM   5994 O OG    . SER D 4 379 ? 149.574 152.140 139.212 1.00 67.13  ? 216 SER R OG    1 
ATOM   5995 N N     . HIS D 4 380 ? 150.862 155.049 140.028 1.00 65.73  ? 217 HIS R N     1 
ATOM   5996 C CA    . HIS D 4 380 ? 150.703 156.240 139.211 1.00 70.96  ? 217 HIS R CA    1 
ATOM   5997 C C     . HIS D 4 380 ? 151.665 157.336 139.649 1.00 73.86  ? 217 HIS R C     1 
ATOM   5998 O O     . HIS D 4 380 ? 152.047 157.427 140.818 1.00 74.25  ? 217 HIS R O     1 
ATOM   5999 C CB    . HIS D 4 380 ? 149.264 156.751 139.286 1.00 64.04  ? 217 HIS R CB    1 
ATOM   6000 C CG    . HIS D 4 380 ? 148.278 155.894 138.555 1.00 69.95  ? 217 HIS R CG    1 
ATOM   6001 N ND1   . HIS D 4 380 ? 148.006 154.594 138.922 1.00 69.50  ? 217 HIS R ND1   1 
ATOM   6002 C CD2   . HIS D 4 380 ? 147.492 156.155 137.483 1.00 67.73  ? 217 HIS R CD2   1 
ATOM   6003 C CE1   . HIS D 4 380 ? 147.099 154.089 138.105 1.00 70.06  ? 217 HIS R CE1   1 
ATOM   6004 N NE2   . HIS D 4 380 ? 146.770 155.016 137.223 1.00 69.51  ? 217 HIS R NE2   1 
ATOM   6005 N N     . LEU D 4 381 ? 152.051 158.174 138.689 1.00 80.26  ? 218 LEU R N     1 
ATOM   6006 C CA    . LEU D 4 381 ? 152.911 159.319 138.956 1.00 80.08  ? 218 LEU R CA    1 
ATOM   6007 C C     . LEU D 4 381 ? 152.132 160.546 139.411 1.00 84.72  ? 218 LEU R C     1 
ATOM   6008 O O     . LEU D 4 381 ? 152.747 161.589 139.658 1.00 84.66  ? 218 LEU R O     1 
ATOM   6009 C CB    . LEU D 4 381 ? 153.732 159.663 137.710 1.00 78.55  ? 218 LEU R CB    1 
ATOM   6010 N N     . LYS D 4 382 ? 150.811 160.445 139.511 1.00 88.78  ? 219 LYS R N     1 
ATOM   6011 C CA    . LYS D 4 382 ? 149.933 161.530 139.969 1.00 89.35  ? 219 LYS R CA    1 
ATOM   6012 C C     . LYS D 4 382 ? 150.044 162.692 138.977 1.00 88.44  ? 219 LYS R C     1 
ATOM   6013 O O     . LYS D 4 382 ? 150.303 162.479 137.785 1.00 83.03  ? 219 LYS R O     1 
ATOM   6014 C CB    . LYS D 4 382 ? 150.256 161.889 141.411 1.00 86.31  ? 219 LYS R CB    1 
ATOM   6015 N N     . SER D 4 383 ? 149.840 163.919 139.463 1.00 89.51  ? 220 SER R N     1 
ATOM   6016 C CA    . SER D 4 383 ? 149.872 165.127 138.636 1.00 86.20  ? 220 SER R CA    1 
ATOM   6017 C C     . SER D 4 383 ? 148.841 165.071 137.511 1.00 85.83  ? 220 SER R C     1 
ATOM   6018 O O     . SER D 4 383 ? 149.048 165.638 136.436 1.00 86.84  ? 220 SER R O     1 
ATOM   6019 C CB    . SER D 4 383 ? 151.272 165.382 138.069 1.00 83.21  ? 220 SER R CB    1 
ATOM   6020 N N     . SER D 4 384 ? 147.724 164.389 137.752 1.00 69.18  ? 221 SER R N     1 
ATOM   6021 C CA    . SER D 4 384 ? 146.659 164.279 136.767 1.00 68.93  ? 221 SER R CA    1 
ATOM   6022 C C     . SER D 4 384 ? 145.341 164.051 137.490 1.00 68.94  ? 221 SER R C     1 
ATOM   6023 O O     . SER D 4 384 ? 145.293 163.378 138.523 1.00 67.33  ? 221 SER R O     1 
ATOM   6024 C CB    . SER D 4 384 ? 146.926 163.145 135.770 1.00 68.08  ? 221 SER R CB    1 
ATOM   6025 N N     . ARG D 4 385 ? 144.269 164.624 136.936 1.00 64.41  ? 222 ARG R N     1 
ATOM   6026 C CA    . ARG D 4 385 ? 142.952 164.471 137.547 1.00 65.14  ? 222 ARG R CA    1 
ATOM   6027 C C     . ARG D 4 385 ? 142.501 163.016 137.537 1.00 67.78  ? 222 ARG R C     1 
ATOM   6028 O O     . ARG D 4 385 ? 141.978 162.513 138.539 1.00 68.33  ? 222 ARG R O     1 
ATOM   6029 C CB    . ARG D 4 385 ? 141.934 165.355 136.827 1.00 63.49  ? 222 ARG R CB    1 
ATOM   6030 N N     . ASN D 4 386 ? 142.696 162.323 136.412 1.00 65.92  ? 223 ASN R N     1 
ATOM   6031 C CA    . ASN D 4 386 ? 142.304 160.919 136.329 1.00 61.66  ? 223 ASN R CA    1 
ATOM   6032 C C     . ASN D 4 386 ? 143.117 160.060 137.289 1.00 63.10  ? 223 ASN R C     1 
ATOM   6033 O O     . ASN D 4 386 ? 142.573 159.164 137.945 1.00 68.24  ? 223 ASN R O     1 
ATOM   6034 C CB    . ASN D 4 386 ? 142.461 160.411 134.897 1.00 65.57  ? 223 ASN R CB    1 
ATOM   6035 C CG    . ASN D 4 386 ? 142.364 158.901 134.803 1.00 66.93  ? 223 ASN R CG    1 
ATOM   6036 O OD1   . ASN D 4 386 ? 141.285 158.327 134.941 1.00 68.12  ? 223 ASN R OD1   1 
ATOM   6037 N ND2   . ASN D 4 386 ? 143.498 158.248 134.575 1.00 67.58  ? 223 ASN R ND2   1 
ATOM   6038 N N     . SER D 4 387 ? 144.425 160.313 137.376 1.00 61.05  ? 224 SER R N     1 
ATOM   6039 C CA    . SER D 4 387 ? 145.269 159.551 138.291 1.00 62.75  ? 224 SER R CA    1 
ATOM   6040 C C     . SER D 4 387 ? 144.843 159.761 139.738 1.00 57.90  ? 224 SER R C     1 
ATOM   6041 O O     . SER D 4 387 ? 144.750 158.799 140.514 1.00 54.68  ? 224 SER R O     1 
ATOM   6042 C CB    . SER D 4 387 ? 146.732 159.948 138.101 1.00 62.53  ? 224 SER R CB    1 
ATOM   6043 O OG    . SER D 4 387 ? 147.550 159.367 139.098 1.00 62.98  ? 224 SER R OG    1 
ATOM   6044 N N     . THR D 4 388 ? 144.580 161.013 140.120 1.00 60.18  ? 225 THR R N     1 
ATOM   6045 C CA    . THR D 4 388 ? 144.136 161.293 141.481 1.00 57.78  ? 225 THR R CA    1 
ATOM   6046 C C     . THR D 4 388 ? 142.793 160.637 141.766 1.00 57.33  ? 225 THR R C     1 
ATOM   6047 O O     . THR D 4 388 ? 142.583 160.084 142.851 1.00 61.49  ? 225 THR R O     1 
ATOM   6048 C CB    . THR D 4 388 ? 144.053 162.801 141.712 1.00 61.95  ? 225 THR R CB    1 
ATOM   6049 O OG1   . THR D 4 388 ? 143.335 163.414 140.635 1.00 65.32  ? 225 THR R OG1   1 
ATOM   6050 C CG2   . THR D 4 388 ? 145.448 163.405 141.798 1.00 61.46  ? 225 THR R CG2   1 
ATOM   6051 N N     . SER D 4 389 ? 141.869 160.685 140.802 1.00 53.97  ? 226 SER R N     1 
ATOM   6052 C CA    . SER D 4 389 ? 140.569 160.052 140.996 1.00 50.30  ? 226 SER R CA    1 
ATOM   6053 C C     . SER D 4 389 ? 140.709 158.545 141.169 1.00 52.96  ? 226 SER R C     1 
ATOM   6054 O O     . SER D 4 389 ? 140.070 157.953 142.047 1.00 59.79  ? 226 SER R O     1 
ATOM   6055 C CB    . SER D 4 389 ? 139.646 160.373 139.821 1.00 55.64  ? 226 SER R CB    1 
ATOM   6056 O OG    . SER D 4 389 ? 139.872 159.486 138.739 1.00 61.31  ? 226 SER R OG    1 
ATOM   6057 N N     . VAL D 4 390 ? 141.548 157.909 140.348 1.00 50.69  ? 227 VAL R N     1 
ATOM   6058 C CA    . VAL D 4 390 ? 141.741 156.464 140.445 1.00 50.70  ? 227 VAL R CA    1 
ATOM   6059 C C     . VAL D 4 390 ? 142.349 156.099 141.794 1.00 54.75  ? 227 VAL R C     1 
ATOM   6060 O O     . VAL D 4 390 ? 141.893 155.166 142.470 1.00 52.25  ? 227 VAL R O     1 
ATOM   6061 C CB    . VAL D 4 390 ? 142.613 155.960 139.280 1.00 46.26  ? 227 VAL R CB    1 
ATOM   6062 C CG1   . VAL D 4 390 ? 143.126 154.557 139.564 1.00 46.96  ? 227 VAL R CG1   1 
ATOM   6063 C CG2   . VAL D 4 390 ? 141.828 155.988 137.978 1.00 53.31  ? 227 VAL R CG2   1 
ATOM   6064 N N     . LYS D 4 391 ? 143.387 156.832 142.206 1.00 56.58  ? 228 LYS R N     1 
ATOM   6065 C CA    . LYS D 4 391 ? 144.030 156.545 143.484 1.00 48.86  ? 228 LYS R CA    1 
ATOM   6066 C C     . LYS D 4 391 ? 143.061 156.735 144.643 1.00 44.56  ? 228 LYS R C     1 
ATOM   6067 O O     . LYS D 4 391 ? 142.991 155.893 145.547 1.00 48.87  ? 228 LYS R O     1 
ATOM   6068 C CB    . LYS D 4 391 ? 145.262 157.430 143.666 1.00 53.70  ? 228 LYS R CB    1 
ATOM   6069 C CG    . LYS D 4 391 ? 146.536 156.859 143.069 1.00 52.47  ? 228 LYS R CG    1 
ATOM   6070 C CD    . LYS D 4 391 ? 147.749 157.675 143.487 1.00 54.00  ? 228 LYS R CD    1 
ATOM   6071 C CE    . LYS D 4 391 ? 149.037 157.065 142.959 1.00 54.98  ? 228 LYS R CE    1 
ATOM   6072 N NZ    . LYS D 4 391 ? 150.236 157.834 143.393 1.00 56.40  ? 228 LYS R NZ    1 
ATOM   6073 N N     . LYS D 4 392 ? 142.298 157.831 144.630 1.00 47.57  ? 229 LYS R N     1 
ATOM   6074 C CA    . LYS D 4 392 ? 141.348 158.088 145.706 1.00 48.35  ? 229 LYS R CA    1 
ATOM   6075 C C     . LYS D 4 392 ? 140.269 157.017 145.757 1.00 44.17  ? 229 LYS R C     1 
ATOM   6076 O O     . LYS D 4 392 ? 139.916 156.538 146.839 1.00 47.06  ? 229 LYS R O     1 
ATOM   6077 C CB    . LYS D 4 392 ? 140.723 159.472 145.536 1.00 46.60  ? 229 LYS R CB    1 
ATOM   6078 N N     . LYS D 4 393 ? 139.739 156.619 144.598 1.00 34.63  ? 230 LYS R N     1 
ATOM   6079 C CA    . LYS D 4 393 ? 138.689 155.606 144.575 1.00 40.64  ? 230 LYS R CA    1 
ATOM   6080 C C     . LYS D 4 393 ? 139.205 154.267 145.088 1.00 47.45  ? 230 LYS R C     1 
ATOM   6081 O O     . LYS D 4 393 ? 138.552 153.611 145.909 1.00 45.89  ? 230 LYS R O     1 
ATOM   6082 C CB    . LYS D 4 393 ? 138.130 155.465 143.159 1.00 38.41  ? 230 LYS R CB    1 
ATOM   6083 N N     . SER D 4 394 ? 140.384 153.847 144.619 1.00 41.36  ? 231 SER R N     1 
ATOM   6084 C CA    . SER D 4 394 ? 140.938 152.572 145.065 1.00 34.38  ? 231 SER R CA    1 
ATOM   6085 C C     . SER D 4 394 ? 141.238 152.591 146.559 1.00 41.24  ? 231 SER R C     1 
ATOM   6086 O O     . SER D 4 394 ? 140.920 151.632 147.277 1.00 42.38  ? 231 SER R O     1 
ATOM   6087 C CB    . SER D 4 394 ? 142.197 152.240 144.266 1.00 31.28  ? 231 SER R CB    1 
ATOM   6088 O OG    . SER D 4 394 ? 143.181 153.246 144.423 1.00 43.11  ? 231 SER R OG    1 
ATOM   6089 N N     . SER D 4 395 ? 141.846 153.676 147.048 1.00 45.08  ? 232 SER R N     1 
ATOM   6090 C CA    . SER D 4 395 ? 142.161 153.767 148.468 1.00 36.23  ? 232 SER R CA    1 
ATOM   6091 C C     . SER D 4 395 ? 140.896 153.780 149.314 1.00 44.75  ? 232 SER R C     1 
ATOM   6092 O O     . SER D 4 395 ? 140.839 153.131 150.363 1.00 51.01  ? 232 SER R O     1 
ATOM   6093 C CB    . SER D 4 395 ? 143.004 155.012 148.740 1.00 44.28  ? 232 SER R CB    1 
ATOM   6094 O OG    . SER D 4 395 ? 144.172 155.022 147.937 1.00 50.94  ? 232 SER R OG    1 
ATOM   6095 N N     . ARG D 4 396 ? 139.867 154.509 148.873 1.00 40.58  ? 233 ARG R N     1 
ATOM   6096 C CA    . ARG D 4 396 ? 138.614 154.548 149.617 1.00 45.16  ? 233 ARG R CA    1 
ATOM   6097 C C     . ARG D 4 396 ? 137.954 153.178 149.657 1.00 46.33  ? 233 ARG R C     1 
ATOM   6098 O O     . ARG D 4 396 ? 137.449 152.759 150.703 1.00 45.99  ? 233 ARG R O     1 
ATOM   6099 C CB    . ARG D 4 396 ? 137.670 155.582 149.002 1.00 39.37  ? 233 ARG R CB    1 
ATOM   6100 N N     . ASN D 4 397 ? 137.951 152.461 148.530 1.00 37.01  ? 234 ASN R N     1 
ATOM   6101 C CA    . ASN D 4 397 ? 137.351 151.131 148.509 1.00 32.51  ? 234 ASN R CA    1 
ATOM   6102 C C     . ASN D 4 397 ? 138.098 150.171 149.429 1.00 34.01  ? 234 ASN R C     1 
ATOM   6103 O O     . ASN D 4 397 ? 137.476 149.422 150.195 1.00 42.98  ? 234 ASN R O     1 
ATOM   6104 C CB    . ASN D 4 397 ? 137.320 150.593 147.079 1.00 39.49  ? 234 ASN R CB    1 
ATOM   6105 C CG    . ASN D 4 397 ? 136.447 151.428 146.164 1.00 46.00  ? 234 ASN R CG    1 
ATOM   6106 O OD1   . ASN D 4 397 ? 135.337 151.813 146.529 1.00 48.18  ? 234 ASN R OD1   1 
ATOM   6107 N ND2   . ASN D 4 397 ? 136.947 151.714 144.969 1.00 46.06  ? 234 ASN R ND2   1 
ATOM   6108 N N     . ILE D 4 398 ? 139.433 150.183 149.375 1.00 35.13  ? 235 ILE R N     1 
ATOM   6109 C CA    . ILE D 4 398 ? 140.213 149.283 150.222 1.00 31.54  ? 235 ILE R CA    1 
ATOM   6110 C C     . ILE D 4 398 ? 140.015 149.627 151.693 1.00 34.96  ? 235 ILE R C     1 
ATOM   6111 O O     . ILE D 4 398 ? 139.854 148.736 152.540 1.00 34.68  ? 235 ILE R O     1 
ATOM   6112 C CB    . ILE D 4 398 ? 141.699 149.325 149.823 1.00 27.60  ? 235 ILE R CB    1 
ATOM   6113 C CG1   . ILE D 4 398 ? 141.884 148.769 148.412 1.00 31.14  ? 235 ILE R CG1   1 
ATOM   6114 C CG2   . ILE D 4 398 ? 142.539 148.535 150.812 1.00 31.69  ? 235 ILE R CG2   1 
ATOM   6115 C CD1   . ILE D 4 398 ? 143.217 149.110 147.801 1.00 42.86  ? 235 ILE R CD1   1 
ATOM   6116 N N     . PHE D 4 399 ? 140.031 150.921 152.023 1.00 39.92  ? 236 PHE R N     1 
ATOM   6117 C CA    . PHE D 4 399 ? 139.825 151.337 153.405 1.00 35.70  ? 236 PHE R CA    1 
ATOM   6118 C C     . PHE D 4 399 ? 138.438 150.950 153.894 1.00 42.32  ? 236 PHE R C     1 
ATOM   6119 O O     . PHE D 4 399 ? 138.280 150.513 155.036 1.00 47.57  ? 236 PHE R O     1 
ATOM   6120 C CB    . PHE D 4 399 ? 140.038 152.844 153.541 1.00 43.41  ? 236 PHE R CB    1 
ATOM   6121 C CG    . PHE D 4 399 ? 139.805 153.363 154.931 1.00 54.79  ? 236 PHE R CG    1 
ATOM   6122 C CD1   . PHE D 4 399 ? 140.747 153.165 155.926 1.00 57.22  ? 236 PHE R CD1   1 
ATOM   6123 C CD2   . PHE D 4 399 ? 138.640 154.044 155.244 1.00 50.05  ? 236 PHE R CD2   1 
ATOM   6124 C CE1   . PHE D 4 399 ? 140.534 153.639 157.207 1.00 51.77  ? 236 PHE R CE1   1 
ATOM   6125 C CE2   . PHE D 4 399 ? 138.421 154.521 156.522 1.00 51.77  ? 236 PHE R CE2   1 
ATOM   6126 C CZ    . PHE D 4 399 ? 139.370 154.318 157.505 1.00 55.49  ? 236 PHE R CZ    1 
ATOM   6127 N N     . SER D 4 400 ? 137.419 151.108 153.047 1.00 39.98  ? 237 SER R N     1 
ATOM   6128 C CA    . SER D 4 400 ? 136.071 150.711 153.434 1.00 38.22  ? 237 SER R CA    1 
ATOM   6129 C C     . SER D 4 400 ? 135.991 149.213 153.687 1.00 38.52  ? 237 SER R C     1 
ATOM   6130 O O     . SER D 4 400 ? 135.380 148.777 154.669 1.00 43.29  ? 237 SER R O     1 
ATOM   6131 C CB    . SER D 4 400 ? 135.069 151.129 152.358 1.00 31.07  ? 237 SER R CB    1 
ATOM   6132 O OG    . SER D 4 400 ? 135.021 152.538 152.226 1.00 40.67  ? 237 SER R OG    1 
ATOM   6133 N N     . ILE D 4 401 ? 136.613 148.410 152.820 1.00 37.18  ? 238 ILE R N     1 
ATOM   6134 C CA    . ILE D 4 401 ? 136.598 146.960 153.009 1.00 31.84  ? 238 ILE R CA    1 
ATOM   6135 C C     . ILE D 4 401 ? 137.263 146.589 154.329 1.00 33.93  ? 238 ILE R C     1 
ATOM   6136 O O     . ILE D 4 401 ? 136.707 145.834 155.139 1.00 44.06  ? 238 ILE R O     1 
ATOM   6137 C CB    . ILE D 4 401 ? 137.280 146.256 151.821 1.00 24.67  ? 238 ILE R CB    1 
ATOM   6138 C CG1   . ILE D 4 401 ? 136.383 146.295 150.584 1.00 32.75  ? 238 ILE R CG1   1 
ATOM   6139 C CG2   . ILE D 4 401 ? 137.628 144.821 152.181 1.00 30.35  ? 238 ILE R CG2   1 
ATOM   6140 C CD1   . ILE D 4 401 ? 137.135 146.149 149.282 1.00 32.12  ? 238 ILE R CD1   1 
ATOM   6141 N N     . VAL D 4 402 ? 138.460 147.128 154.571 1.00 34.55  ? 239 VAL R N     1 
ATOM   6142 C CA    . VAL D 4 402 ? 139.193 146.787 155.788 1.00 30.95  ? 239 VAL R CA    1 
ATOM   6143 C C     . VAL D 4 402 ? 138.428 147.250 157.021 1.00 38.66  ? 239 VAL R C     1 
ATOM   6144 O O     . VAL D 4 402 ? 138.318 146.518 158.012 1.00 48.71  ? 239 VAL R O     1 
ATOM   6145 C CB    . VAL D 4 402 ? 140.613 147.382 155.742 1.00 40.20  ? 239 VAL R CB    1 
ATOM   6146 C CG1   . VAL D 4 402 ? 141.320 147.173 157.071 1.00 37.82  ? 239 VAL R CG1   1 
ATOM   6147 C CG2   . VAL D 4 402 ? 141.410 146.756 154.610 1.00 40.44  ? 239 VAL R CG2   1 
ATOM   6148 N N     . PHE D 4 403 ? 137.880 148.467 156.978 1.00 37.27  ? 240 PHE R N     1 
ATOM   6149 C CA    . PHE D 4 403 ? 137.166 149.013 158.125 1.00 42.59  ? 240 PHE R CA    1 
ATOM   6150 C C     . PHE D 4 403 ? 135.907 148.215 158.432 1.00 44.65  ? 240 PHE R C     1 
ATOM   6151 O O     . PHE D 4 403 ? 135.628 147.919 159.600 1.00 51.40  ? 240 PHE R O     1 
ATOM   6152 C CB    . PHE D 4 403 ? 136.827 150.481 157.869 1.00 46.54  ? 240 PHE R CB    1 
ATOM   6153 C CG    . PHE D 4 403 ? 136.073 151.137 158.988 1.00 47.18  ? 240 PHE R CG    1 
ATOM   6154 C CD1   . PHE D 4 403 ? 136.722 151.514 160.151 1.00 43.23  ? 240 PHE R CD1   1 
ATOM   6155 C CD2   . PHE D 4 403 ? 134.715 151.385 158.874 1.00 46.78  ? 240 PHE R CD2   1 
ATOM   6156 C CE1   . PHE D 4 403 ? 136.031 152.121 161.181 1.00 44.99  ? 240 PHE R CE1   1 
ATOM   6157 C CE2   . PHE D 4 403 ? 134.019 151.992 159.900 1.00 47.76  ? 240 PHE R CE2   1 
ATOM   6158 C CZ    . PHE D 4 403 ? 134.678 152.360 161.055 1.00 49.42  ? 240 PHE R CZ    1 
ATOM   6159 N N     . VAL D 4 404 ? 135.128 147.860 157.406 1.00 32.87  ? 241 VAL R N     1 
ATOM   6160 C CA    . VAL D 4 404 ? 133.907 147.104 157.657 1.00 42.28  ? 241 VAL R CA    1 
ATOM   6161 C C     . VAL D 4 404 ? 134.242 145.713 158.179 1.00 48.64  ? 241 VAL R C     1 
ATOM   6162 O O     . VAL D 4 404 ? 133.603 145.225 159.118 1.00 45.43  ? 241 VAL R O     1 
ATOM   6163 C CB    . VAL D 4 404 ? 133.013 147.058 156.401 1.00 35.19  ? 241 VAL R CB    1 
ATOM   6164 C CG1   . VAL D 4 404 ? 133.634 146.229 155.289 1.00 44.84  ? 241 VAL R CG1   1 
ATOM   6165 C CG2   . VAL D 4 404 ? 131.644 146.514 156.755 1.00 40.37  ? 241 VAL R CG2   1 
ATOM   6166 N N     . PHE D 4 405 ? 135.267 145.067 157.612 1.00 39.48  ? 242 PHE R N     1 
ATOM   6167 C CA    . PHE D 4 405 ? 135.676 143.759 158.112 1.00 23.36  ? 242 PHE R CA    1 
ATOM   6168 C C     . PHE D 4 405 ? 136.081 143.843 159.578 1.00 31.08  ? 242 PHE R C     1 
ATOM   6169 O O     . PHE D 4 405 ? 135.603 143.065 160.415 1.00 51.66  ? 242 PHE R O     1 
ATOM   6170 C CB    . PHE D 4 405 ? 136.824 143.218 157.258 1.00 25.64  ? 242 PHE R CB    1 
ATOM   6171 C CG    . PHE D 4 405 ? 137.144 141.773 157.509 1.00 34.32  ? 242 PHE R CG    1 
ATOM   6172 C CD1   . PHE D 4 405 ? 136.430 140.772 156.873 1.00 36.02  ? 242 PHE R CD1   1 
ATOM   6173 C CD2   . PHE D 4 405 ? 138.168 141.415 158.369 1.00 38.12  ? 242 PHE R CD2   1 
ATOM   6174 C CE1   . PHE D 4 405 ? 136.725 139.442 157.097 1.00 35.51  ? 242 PHE R CE1   1 
ATOM   6175 C CE2   . PHE D 4 405 ? 138.467 140.086 158.596 1.00 35.39  ? 242 PHE R CE2   1 
ATOM   6176 C CZ    . PHE D 4 405 ? 137.745 139.099 157.958 1.00 32.91  ? 242 PHE R CZ    1 
ATOM   6177 N N     . PHE D 4 406 ? 136.937 144.814 159.909 1.00 32.24  ? 243 PHE R N     1 
ATOM   6178 C CA    . PHE D 4 406 ? 137.404 144.971 161.281 1.00 44.03  ? 243 PHE R CA    1 
ATOM   6179 C C     . PHE D 4 406 ? 136.238 145.208 162.232 1.00 48.00  ? 243 PHE R C     1 
ATOM   6180 O O     . PHE D 4 406 ? 136.042 144.449 163.186 1.00 52.24  ? 243 PHE R O     1 
ATOM   6181 C CB    . PHE D 4 406 ? 138.406 146.127 161.350 1.00 44.70  ? 243 PHE R CB    1 
ATOM   6182 C CG    . PHE D 4 406 ? 139.048 146.306 162.697 1.00 48.47  ? 243 PHE R CG    1 
ATOM   6183 C CD1   . PHE D 4 406 ? 138.461 147.108 163.662 1.00 49.24  ? 243 PHE R CD1   1 
ATOM   6184 C CD2   . PHE D 4 406 ? 140.251 145.688 162.991 1.00 47.46  ? 243 PHE R CD2   1 
ATOM   6185 C CE1   . PHE D 4 406 ? 139.053 147.277 164.898 1.00 54.03  ? 243 PHE R CE1   1 
ATOM   6186 C CE2   . PHE D 4 406 ? 140.848 145.852 164.226 1.00 52.24  ? 243 PHE R CE2   1 
ATOM   6187 C CZ    . PHE D 4 406 ? 140.249 146.649 165.180 1.00 55.60  ? 243 PHE R CZ    1 
ATOM   6188 N N     . VAL D 4 407 ? 135.411 146.215 161.940 1.00 36.24  ? 244 VAL R N     1 
ATOM   6189 C CA    . VAL D 4 407 ? 134.337 146.592 162.854 1.00 40.78  ? 244 VAL R CA    1 
ATOM   6190 C C     . VAL D 4 407 ? 133.344 145.450 163.022 1.00 48.43  ? 244 VAL R C     1 
ATOM   6191 O O     . VAL D 4 407 ? 132.888 145.165 164.136 1.00 47.31  ? 244 VAL R O     1 
ATOM   6192 C CB    . VAL D 4 407 ? 133.646 147.878 162.361 1.00 41.01  ? 244 VAL R CB    1 
ATOM   6193 C CG1   . VAL D 4 407 ? 132.370 148.137 163.147 1.00 42.86  ? 244 VAL R CG1   1 
ATOM   6194 C CG2   . VAL D 4 407 ? 134.593 149.060 162.478 1.00 48.19  ? 244 VAL R CG2   1 
ATOM   6195 N N     . CYS D 4 408 ? 133.001 144.768 161.927 1.00 45.17  ? 245 CYS R N     1 
ATOM   6196 C CA    . CYS D 4 408 ? 131.972 143.741 162.004 1.00 38.44  ? 245 CYS R CA    1 
ATOM   6197 C C     . CYS D 4 408 ? 132.474 142.466 162.668 1.00 44.66  ? 245 CYS R C     1 
ATOM   6198 O O     . CYS D 4 408 ? 131.686 141.761 163.308 1.00 53.00  ? 245 CYS R O     1 
ATOM   6199 C CB    . CYS D 4 408 ? 131.438 143.434 160.607 1.00 35.42  ? 245 CYS R CB    1 
ATOM   6200 S SG    . CYS D 4 408 ? 130.484 144.780 159.870 1.00 52.71  ? 245 CYS R SG    1 
ATOM   6201 N N     . PHE D 4 409 ? 133.761 142.142 162.542 1.00 35.84  ? 246 PHE R N     1 
ATOM   6202 C CA    . PHE D 4 409 ? 134.211 140.812 162.937 1.00 29.63  ? 246 PHE R CA    1 
ATOM   6203 C C     . PHE D 4 409 ? 135.192 140.783 164.100 1.00 28.90  ? 246 PHE R C     1 
ATOM   6204 O O     . PHE D 4 409 ? 135.118 139.867 164.922 1.00 46.42  ? 246 PHE R O     1 
ATOM   6205 C CB    . PHE D 4 409 ? 134.834 140.105 161.732 1.00 31.57  ? 246 PHE R CB    1 
ATOM   6206 C CG    . PHE D 4 409 ? 133.847 139.772 160.652 1.00 23.17  ? 246 PHE R CG    1 
ATOM   6207 C CD1   . PHE D 4 409 ? 132.798 138.904 160.901 1.00 32.06  ? 246 PHE R CD1   1 
ATOM   6208 C CD2   . PHE D 4 409 ? 133.965 140.328 159.391 1.00 29.55  ? 246 PHE R CD2   1 
ATOM   6209 C CE1   . PHE D 4 409 ? 131.886 138.596 159.912 1.00 38.66  ? 246 PHE R CE1   1 
ATOM   6210 C CE2   . PHE D 4 409 ? 133.056 140.023 158.397 1.00 31.09  ? 246 PHE R CE2   1 
ATOM   6211 C CZ    . PHE D 4 409 ? 132.016 139.155 158.659 1.00 33.81  ? 246 PHE R CZ    1 
ATOM   6212 N N     . VAL D 4 410 ? 136.121 141.739 164.197 1.00 31.06  ? 247 VAL R N     1 
ATOM   6213 C CA    . VAL D 4 410 ? 137.171 141.650 165.216 1.00 42.11  ? 247 VAL R CA    1 
ATOM   6214 C C     . VAL D 4 410 ? 136.613 141.635 166.635 1.00 42.04  ? 247 VAL R C     1 
ATOM   6215 O O     . VAL D 4 410 ? 137.059 140.800 167.440 1.00 44.48  ? 247 VAL R O     1 
ATOM   6216 C CB    . VAL D 4 410 ? 138.211 142.763 164.998 1.00 37.55  ? 247 VAL R CB    1 
ATOM   6217 C CG1   . VAL D 4 410 ? 139.175 142.831 166.170 1.00 41.27  ? 247 VAL R CG1   1 
ATOM   6218 C CG2   . VAL D 4 410 ? 138.965 142.524 163.702 1.00 41.81  ? 247 VAL R CG2   1 
ATOM   6219 N N     . PRO D 4 411 ? 135.675 142.514 167.021 1.00 35.93  ? 248 PRO R N     1 
ATOM   6220 C CA    . PRO D 4 411 ? 135.123 142.405 168.384 1.00 43.45  ? 248 PRO R CA    1 
ATOM   6221 C C     . PRO D 4 411 ? 134.502 141.050 168.672 1.00 47.50  ? 248 PRO R C     1 
ATOM   6222 O O     . PRO D 4 411 ? 134.679 140.510 169.773 1.00 44.73  ? 248 PRO R O     1 
ATOM   6223 C CB    . PRO D 4 411 ? 134.082 143.533 168.429 1.00 38.73  ? 248 PRO R CB    1 
ATOM   6224 C CG    . PRO D 4 411 ? 134.552 144.512 167.425 1.00 43.13  ? 248 PRO R CG    1 
ATOM   6225 C CD    . PRO D 4 411 ? 135.133 143.691 166.317 1.00 36.78  ? 248 PRO R CD    1 
ATOM   6226 N N     . TYR D 4 412 ? 133.801 140.468 167.696 1.00 44.13  ? 249 TYR R N     1 
ATOM   6227 C CA    . TYR D 4 412 ? 133.191 139.163 167.920 1.00 36.02  ? 249 TYR R CA    1 
ATOM   6228 C C     . TYR D 4 412 ? 134.243 138.093 168.156 1.00 38.64  ? 249 TYR R C     1 
ATOM   6229 O O     . TYR D 4 412 ? 134.081 137.238 169.031 1.00 56.78  ? 249 TYR R O     1 
ATOM   6230 C CB    . TYR D 4 412 ? 132.299 138.770 166.745 1.00 36.96  ? 249 TYR R CB    1 
ATOM   6231 C CG    . TYR D 4 412 ? 131.903 137.313 166.802 1.00 32.77  ? 249 TYR R CG    1 
ATOM   6232 C CD1   . TYR D 4 412 ? 131.132 136.826 167.848 1.00 33.84  ? 249 TYR R CD1   1 
ATOM   6233 C CD2   . TYR D 4 412 ? 132.326 136.419 165.830 1.00 36.05  ? 249 TYR R CD2   1 
ATOM   6234 C CE1   . TYR D 4 412 ? 130.778 135.495 167.915 1.00 38.14  ? 249 TYR R CE1   1 
ATOM   6235 C CE2   . TYR D 4 412 ? 131.977 135.086 165.888 1.00 36.27  ? 249 TYR R CE2   1 
ATOM   6236 C CZ    . TYR D 4 412 ? 131.204 134.630 166.933 1.00 32.68  ? 249 TYR R CZ    1 
ATOM   6237 O OH    . TYR D 4 412 ? 130.854 133.302 166.996 1.00 39.35  ? 249 TYR R OH    1 
ATOM   6238 N N     . HIS D 4 413 ? 135.327 138.118 167.390 1.00 19.69  ? 250 HIS R N     1 
ATOM   6239 C CA    . HIS D 4 413 ? 136.335 137.077 167.502 1.00 24.03  ? 250 HIS R CA    1 
ATOM   6240 C C     . HIS D 4 413 ? 137.346 137.338 168.608 1.00 41.35  ? 250 HIS R C     1 
ATOM   6241 O O     . HIS D 4 413 ? 138.171 136.463 168.889 1.00 45.25  ? 250 HIS R O     1 
ATOM   6242 C CB    . HIS D 4 413 ? 137.049 136.897 166.164 1.00 26.64  ? 250 HIS R CB    1 
ATOM   6243 C CG    . HIS D 4 413 ? 136.173 136.323 165.096 1.00 20.43  ? 250 HIS R CG    1 
ATOM   6244 N ND1   . HIS D 4 413 ? 135.374 137.103 164.289 1.00 25.32  ? 250 HIS R ND1   1 
ATOM   6245 C CD2   . HIS D 4 413 ? 135.966 135.043 164.705 1.00 31.78  ? 250 HIS R CD2   1 
ATOM   6246 C CE1   . HIS D 4 413 ? 134.715 136.330 163.445 1.00 34.96  ? 250 HIS R CE1   1 
ATOM   6247 N NE2   . HIS D 4 413 ? 135.056 135.076 163.676 1.00 40.31  ? 250 HIS R NE2   1 
ATOM   6248 N N     . ILE D 4 414 ? 137.307 138.512 169.241 1.00 47.50  ? 251 ILE R N     1 
ATOM   6249 C CA    . ILE D 4 414 ? 138.046 138.696 170.484 1.00 44.84  ? 251 ILE R CA    1 
ATOM   6250 C C     . ILE D 4 414 ? 137.168 138.464 171.710 1.00 46.04  ? 251 ILE R C     1 
ATOM   6251 O O     . ILE D 4 414 ? 137.701 138.269 172.811 1.00 47.75  ? 251 ILE R O     1 
ATOM   6252 C CB    . ILE D 4 414 ? 138.694 140.091 170.567 1.00 42.18  ? 251 ILE R CB    1 
ATOM   6253 C CG1   . ILE D 4 414 ? 137.631 141.178 170.726 1.00 48.37  ? 251 ILE R CG1   1 
ATOM   6254 C CG2   . ILE D 4 414 ? 139.568 140.352 169.351 1.00 39.63  ? 251 ILE R CG2   1 
ATOM   6255 C CD1   . ILE D 4 414 ? 138.203 142.560 170.946 1.00 45.30  ? 251 ILE R CD1   1 
ATOM   6256 N N     . ALA D 4 415 ? 135.842 138.478 171.554 1.00 48.58  ? 252 ALA R N     1 
ATOM   6257 C CA    . ALA D 4 415 ? 134.942 138.192 172.662 1.00 50.64  ? 252 ALA R CA    1 
ATOM   6258 C C     . ALA D 4 415 ? 134.402 136.765 172.661 1.00 53.35  ? 252 ALA R C     1 
ATOM   6259 O O     . ALA D 4 415 ? 133.824 136.342 173.668 1.00 65.18  ? 252 ALA R O     1 
ATOM   6260 C CB    . ALA D 4 415 ? 133.765 139.176 172.654 1.00 53.33  ? 252 ALA R CB    1 
ATOM   6261 N N     . ARG D 4 416 ? 134.565 136.020 171.566 1.00 39.48  ? 253 ARG R N     1 
ATOM   6262 C CA    . ARG D 4 416 ? 134.008 134.672 171.491 1.00 45.08  ? 253 ARG R CA    1 
ATOM   6263 C C     . ARG D 4 416 ? 134.727 133.718 172.436 1.00 55.67  ? 253 ARG R C     1 
ATOM   6264 O O     . ARG D 4 416 ? 134.087 132.953 173.166 1.00 54.08  ? 253 ARG R O     1 
ATOM   6265 C CB    . ARG D 4 416 ? 134.077 134.158 170.051 1.00 41.90  ? 253 ARG R CB    1 
ATOM   6266 C CG    . ARG D 4 416 ? 133.402 132.811 169.838 1.00 47.72  ? 253 ARG R CG    1 
ATOM   6267 C CD    . ARG D 4 416 ? 132.052 132.743 170.535 1.00 51.52  ? 253 ARG R CD    1 
ATOM   6268 N NE    . ARG D 4 416 ? 131.319 131.530 170.192 1.00 49.46  ? 253 ARG R NE    1 
ATOM   6269 C CZ    . ARG D 4 416 ? 130.059 131.297 170.529 1.00 45.67  ? 253 ARG R CZ    1 
ATOM   6270 N NH1   . ARG D 4 416 ? 129.350 132.184 171.206 1.00 51.78  ? 253 ARG R NH1   1 
ATOM   6271 N NH2   . ARG D 4 416 ? 129.494 130.147 170.175 1.00 49.32  ? 253 ARG R NH2   1 
ATOM   6272 N N     . ILE D 4 417 ? 136.061 133.739 172.424 1.00 62.80  ? 254 ILE R N     1 
ATOM   6273 C CA    . ILE D 4 417 ? 136.825 132.833 173.283 1.00 57.76  ? 254 ILE R CA    1 
ATOM   6274 C C     . ILE D 4 417 ? 136.477 133.017 174.759 1.00 54.59  ? 254 ILE R C     1 
ATOM   6275 O O     . ILE D 4 417 ? 136.236 132.012 175.442 1.00 63.42  ? 254 ILE R O     1 
ATOM   6276 C CB    . ILE D 4 417 ? 138.329 132.973 172.999 1.00 58.36  ? 254 ILE R CB    1 
ATOM   6277 C CG1   . ILE D 4 417 ? 138.628 132.654 171.533 1.00 56.35  ? 254 ILE R CG1   1 
ATOM   6278 C CG2   . ILE D 4 417 ? 139.131 132.064 173.917 1.00 51.79  ? 254 ILE R CG2   1 
ATOM   6279 C CD1   . ILE D 4 417 ? 138.331 131.227 171.144 1.00 57.15  ? 254 ILE R CD1   1 
ATOM   6280 N N     . PRO D 4 418 ? 136.426 134.239 175.308 1.00 55.10  ? 255 PRO R N     1 
ATOM   6281 C CA    . PRO D 4 418 ? 135.954 134.372 176.696 1.00 58.62  ? 255 PRO R CA    1 
ATOM   6282 C C     . PRO D 4 418 ? 134.550 133.836 176.910 1.00 60.70  ? 255 PRO R C     1 
ATOM   6283 O O     . PRO D 4 418 ? 134.287 133.212 177.943 1.00 68.40  ? 255 PRO R O     1 
ATOM   6284 C CB    . PRO D 4 418 ? 136.033 135.884 176.945 1.00 64.33  ? 255 PRO R CB    1 
ATOM   6285 C CG    . PRO D 4 418 ? 137.087 136.356 176.021 1.00 60.03  ? 255 PRO R CG    1 
ATOM   6286 C CD    . PRO D 4 418 ? 136.922 135.526 174.785 1.00 56.81  ? 255 PRO R CD    1 
ATOM   6287 N N     . TYR D 4 419 ? 133.641 134.025 175.950 1.00 57.93  ? 256 TYR R N     1 
ATOM   6288 C CA    . TYR D 4 419 ? 132.266 133.582 176.161 1.00 63.80  ? 256 TYR R CA    1 
ATOM   6289 C C     . TYR D 4 419 ? 132.142 132.065 176.069 1.00 65.97  ? 256 TYR R C     1 
ATOM   6290 O O     . TYR D 4 419 ? 131.401 131.450 176.846 1.00 75.16  ? 256 TYR R O     1 
ATOM   6291 C CB    . TYR D 4 419 ? 131.324 134.248 175.162 1.00 65.64  ? 256 TYR R CB    1 
ATOM   6292 C CG    . TYR D 4 419 ? 129.913 133.717 175.259 1.00 65.41  ? 256 TYR R CG    1 
ATOM   6293 C CD1   . TYR D 4 419 ? 129.114 134.015 176.354 1.00 68.97  ? 256 TYR R CD1   1 
ATOM   6294 C CD2   . TYR D 4 419 ? 129.387 132.903 174.269 1.00 60.43  ? 256 TYR R CD2   1 
ATOM   6295 C CE1   . TYR D 4 419 ? 127.827 133.524 176.454 1.00 73.04  ? 256 TYR R CE1   1 
ATOM   6296 C CE2   . TYR D 4 419 ? 128.101 132.408 174.360 1.00 59.76  ? 256 TYR R CE2   1 
ATOM   6297 C CZ    . TYR D 4 419 ? 127.325 132.723 175.452 1.00 68.81  ? 256 TYR R CZ    1 
ATOM   6298 O OH    . TYR D 4 419 ? 126.044 132.232 175.545 1.00 71.32  ? 256 TYR R OH    1 
ATOM   6299 N N     . THR D 4 420 ? 132.840 131.441 175.116 1.00 63.91  ? 257 THR R N     1 
ATOM   6300 C CA    . THR D 4 420 ? 132.792 129.985 175.047 1.00 66.87  ? 257 THR R CA    1 
ATOM   6301 C C     . THR D 4 420 ? 133.498 129.355 176.241 1.00 67.32  ? 257 THR R C     1 
ATOM   6302 O O     . THR D 4 420 ? 133.087 128.287 176.706 1.00 66.52  ? 257 THR R O     1 
ATOM   6303 C CB    . THR D 4 420 ? 133.384 129.479 173.728 1.00 63.66  ? 257 THR R CB    1 
ATOM   6304 O OG1   . THR D 4 420 ? 133.245 128.054 173.658 1.00 68.29  ? 257 THR R OG1   1 
ATOM   6305 C CG2   . THR D 4 420 ? 134.850 129.837 173.610 1.00 60.11  ? 257 THR R CG2   1 
ATOM   6306 N N     . LYS D 4 421 ? 134.540 130.007 176.768 1.00 69.44  ? 258 LYS R N     1 
ATOM   6307 C CA    . LYS D 4 421 ? 135.118 129.547 178.026 1.00 69.15  ? 258 LYS R CA    1 
ATOM   6308 C C     . LYS D 4 421 ? 134.127 129.704 179.173 1.00 69.67  ? 258 LYS R C     1 
ATOM   6309 O O     . LYS D 4 421 ? 134.056 128.848 180.062 1.00 74.18  ? 258 LYS R O     1 
ATOM   6310 C CB    . LYS D 4 421 ? 136.412 130.303 178.320 1.00 68.37  ? 258 LYS R CB    1 
ATOM   6311 C CG    . LYS D 4 421 ? 137.594 129.856 177.477 1.00 67.69  ? 258 LYS R CG    1 
ATOM   6312 C CD    . LYS D 4 421 ? 138.895 129.957 178.254 1.00 73.89  ? 258 LYS R CD    1 
ATOM   6313 C CE    . LYS D 4 421 ? 139.164 131.385 178.699 1.00 74.53  ? 258 LYS R CE    1 
ATOM   6314 N NZ    . LYS D 4 421 ? 140.373 131.477 179.563 1.00 73.81  ? 258 LYS R NZ    1 
ATOM   6315 N N     . SER D 4 422 ? 133.355 130.794 179.168 1.00 69.14  ? 259 SER R N     1 
ATOM   6316 C CA    . SER D 4 422 ? 132.362 131.013 180.214 1.00 75.12  ? 259 SER R CA    1 
ATOM   6317 C C     . SER D 4 422 ? 131.281 129.942 180.190 1.00 75.74  ? 259 SER R C     1 
ATOM   6318 O O     . SER D 4 422 ? 130.857 129.455 181.245 1.00 78.55  ? 259 SER R O     1 
ATOM   6319 C CB    . SER D 4 422 ? 131.741 132.401 180.063 1.00 75.40  ? 259 SER R CB    1 
ATOM   6320 O OG    . SER D 4 422 ? 130.720 132.396 179.080 1.00 73.37  ? 259 SER R OG    1 
ATOM   6321 N N     . GLN D 4 423 ? 130.814 129.568 179.003 1.00 68.84  ? 260 GLN R N     1 
ATOM   6322 C CA    . GLN D 4 423 ? 129.775 128.549 178.913 1.00 73.48  ? 260 GLN R CA    1 
ATOM   6323 C C     . GLN D 4 423 ? 130.334 127.137 178.789 1.00 78.23  ? 260 GLN R C     1 
ATOM   6324 O O     . GLN D 4 423 ? 129.556 126.191 178.633 1.00 80.18  ? 260 GLN R O     1 
ATOM   6325 C CB    . GLN D 4 423 ? 128.809 128.843 177.754 1.00 74.42  ? 260 GLN R CB    1 
ATOM   6326 C CG    . GLN D 4 423 ? 129.396 128.887 176.352 1.00 76.89  ? 260 GLN R CG    1 
ATOM   6327 C CD    . GLN D 4 423 ? 128.302 128.975 175.296 1.00 75.30  ? 260 GLN R CD    1 
ATOM   6328 O OE1   . GLN D 4 423 ? 127.130 128.737 175.588 1.00 76.25  ? 260 GLN R OE1   1 
ATOM   6329 N NE2   . GLN D 4 423 ? 128.674 129.328 174.071 1.00 72.15  ? 260 GLN R NE2   1 
ATOM   6330 N N     . THR D 4 424 ? 131.655 126.964 178.858 1.00 77.57  ? 261 THR R N     1 
ATOM   6331 C CA    . THR D 4 424 ? 132.249 125.642 178.994 1.00 77.00  ? 261 THR R CA    1 
ATOM   6332 C C     . THR D 4 424 ? 132.940 125.427 180.334 1.00 77.38  ? 261 THR R C     1 
ATOM   6333 O O     . THR D 4 424 ? 133.333 124.294 180.632 1.00 78.55  ? 261 THR R O     1 
ATOM   6334 C CB    . THR D 4 424 ? 133.253 125.377 177.861 1.00 76.06  ? 261 THR R CB    1 
ATOM   6335 O OG1   . THR D 4 424 ? 134.115 126.510 177.704 1.00 82.11  ? 261 THR R OG1   1 
ATOM   6336 C CG2   . THR D 4 424 ? 132.524 125.108 176.552 1.00 72.41  ? 261 THR R CG2   1 
ATOM   6337 N N     . GLU D 4 425 ? 133.100 126.473 181.142 1.00 82.40  ? 262 GLU R N     1 
ATOM   6338 C CA    . GLU D 4 425 ? 133.673 126.370 182.476 1.00 83.20  ? 262 GLU R CA    1 
ATOM   6339 C C     . GLU D 4 425 ? 132.711 126.978 183.488 1.00 86.29  ? 262 GLU R C     1 
ATOM   6340 O O     . GLU D 4 425 ? 132.133 128.042 183.246 1.00 85.92  ? 262 GLU R O     1 
ATOM   6341 C CB    . GLU D 4 425 ? 135.033 127.072 182.555 1.00 83.05  ? 262 GLU R CB    1 
ATOM   6342 N N     . ALA D 4 426 ? 132.548 126.303 184.624 1.00 96.75  ? 263 ALA R N     1 
ATOM   6343 C CA    . ALA D 4 426 ? 131.558 126.684 185.622 1.00 97.36  ? 263 ALA R CA    1 
ATOM   6344 C C     . ALA D 4 426 ? 132.125 127.545 186.744 1.00 97.95  ? 263 ALA R C     1 
ATOM   6345 O O     . ALA D 4 426 ? 131.404 127.836 187.704 1.00 96.82  ? 263 ALA R O     1 
ATOM   6346 C CB    . ALA D 4 426 ? 130.905 125.433 186.218 1.00 94.91  ? 263 ALA R CB    1 
ATOM   6347 N N     . HIS D 4 427 ? 133.387 127.959 186.655 1.00 100.61 ? 264 HIS R N     1 
ATOM   6348 C CA    . HIS D 4 427 ? 134.027 128.731 187.712 1.00 99.61  ? 264 HIS R CA    1 
ATOM   6349 C C     . HIS D 4 427 ? 134.124 130.218 187.390 1.00 98.26  ? 264 HIS R C     1 
ATOM   6350 O O     . HIS D 4 427 ? 134.855 130.942 188.074 1.00 98.66  ? 264 HIS R O     1 
ATOM   6351 C CB    . HIS D 4 427 ? 135.421 128.172 188.002 1.00 99.50  ? 264 HIS R CB    1 
ATOM   6352 C CG    . HIS D 4 427 ? 136.410 128.411 186.905 1.00 103.02 ? 264 HIS R CG    1 
ATOM   6353 N ND1   . HIS D 4 427 ? 136.410 127.688 185.731 1.00 103.54 ? 264 HIS R ND1   1 
ATOM   6354 C CD2   . HIS D 4 427 ? 137.433 129.293 186.802 1.00 100.23 ? 264 HIS R CD2   1 
ATOM   6355 C CE1   . HIS D 4 427 ? 137.390 128.114 184.954 1.00 101.01 ? 264 HIS R CE1   1 
ATOM   6356 N NE2   . HIS D 4 427 ? 138.025 129.088 185.580 1.00 97.21  ? 264 HIS R NE2   1 
ATOM   6357 N N     . TYR D 4 428 ? 133.410 130.692 186.371 1.00 94.85  ? 265 TYR R N     1 
ATOM   6358 C CA    . TYR D 4 428 ? 133.488 132.084 185.949 1.00 99.09  ? 265 TYR R CA    1 
ATOM   6359 C C     . TYR D 4 428 ? 132.364 132.949 186.509 1.00 98.00  ? 265 TYR R C     1 
ATOM   6360 O O     . TYR D 4 428 ? 132.241 134.109 186.104 1.00 95.95  ? 265 TYR R O     1 
ATOM   6361 C CB    . TYR D 4 428 ? 133.501 132.172 184.421 1.00 97.00  ? 265 TYR R CB    1 
ATOM   6362 C CG    . TYR D 4 428 ? 134.853 131.880 183.808 1.00 97.07  ? 265 TYR R CG    1 
ATOM   6363 C CD1   . TYR D 4 428 ? 136.023 132.104 184.522 1.00 95.43  ? 265 TYR R CD1   1 
ATOM   6364 C CD2   . TYR D 4 428 ? 134.960 131.386 182.515 1.00 95.20  ? 265 TYR R CD2   1 
ATOM   6365 C CE1   . TYR D 4 428 ? 137.261 131.842 183.966 1.00 96.02  ? 265 TYR R CE1   1 
ATOM   6366 C CE2   . TYR D 4 428 ? 136.193 131.120 181.951 1.00 95.60  ? 265 TYR R CE2   1 
ATOM   6367 C CZ    . TYR D 4 428 ? 137.340 131.350 182.681 1.00 97.68  ? 265 TYR R CZ    1 
ATOM   6368 O OH    . TYR D 4 428 ? 138.570 131.087 182.124 1.00 98.19  ? 265 TYR R OH    1 
ATOM   6369 N N     . SER D 4 429 ? 131.540 132.410 187.412 1.00 95.75  ? 266 SER R N     1 
ATOM   6370 C CA    . SER D 4 429 ? 130.483 133.153 188.096 1.00 96.85  ? 266 SER R CA    1 
ATOM   6371 C C     . SER D 4 429 ? 129.372 133.597 187.148 1.00 95.05  ? 266 SER R C     1 
ATOM   6372 O O     . SER D 4 429 ? 129.539 133.583 185.924 1.00 96.97  ? 266 SER R O     1 
ATOM   6373 C CB    . SER D 4 429 ? 131.061 134.365 188.835 1.00 96.46  ? 266 SER R CB    1 
ATOM   6374 O OG    . SER D 4 429 ? 131.219 135.469 187.960 1.00 94.37  ? 266 SER R OG    1 
ATOM   6375 N N     . CYS D 4 430 ? 128.226 133.983 187.713 1.00 93.73  ? 267 CYS R N     1 
ATOM   6376 C CA    . CYS D 4 430 ? 127.062 134.328 186.903 1.00 97.40  ? 267 CYS R CA    1 
ATOM   6377 C C     . CYS D 4 430 ? 127.173 135.719 186.287 1.00 99.13  ? 267 CYS R C     1 
ATOM   6378 O O     . CYS D 4 430 ? 126.735 135.930 185.151 1.00 97.07  ? 267 CYS R O     1 
ATOM   6379 C CB    . CYS D 4 430 ? 125.791 134.225 187.746 1.00 95.67  ? 267 CYS R CB    1 
ATOM   6380 S SG    . CYS D 4 430 ? 125.530 132.604 188.504 1.00 94.80  ? 267 CYS R SG    1 
ATOM   6381 N N     . GLN D 4 431 ? 127.741 136.681 187.018 1.00 96.31  ? 268 GLN R N     1 
ATOM   6382 C CA    . GLN D 4 431 ? 127.771 138.060 186.534 1.00 95.71  ? 268 GLN R CA    1 
ATOM   6383 C C     . GLN D 4 431 ? 128.656 138.198 185.300 1.00 96.75  ? 268 GLN R C     1 
ATOM   6384 O O     . GLN D 4 431 ? 128.252 138.800 184.295 1.00 97.75  ? 268 GLN R O     1 
ATOM   6385 C CB    . GLN D 4 431 ? 128.247 138.994 187.647 1.00 94.82  ? 268 GLN R CB    1 
ATOM   6386 N N     . SER D 4 432 ? 129.872 137.651 185.360 1.00 97.95  ? 269 SER R N     1 
ATOM   6387 C CA    . SER D 4 432 ? 130.762 137.716 184.207 1.00 96.55  ? 269 SER R CA    1 
ATOM   6388 C C     . SER D 4 432 ? 130.197 136.922 183.038 1.00 96.87  ? 269 SER R C     1 
ATOM   6389 O O     . SER D 4 432 ? 130.364 137.311 181.877 1.00 97.28  ? 269 SER R O     1 
ATOM   6390 C CB    . SER D 4 432 ? 132.153 137.208 184.581 1.00 97.75  ? 269 SER R CB    1 
ATOM   6391 O OG    . SER D 4 432 ? 132.129 135.819 184.848 1.00 96.38  ? 269 SER R OG    1 
ATOM   6392 N N     . LYS D 4 433 ? 129.523 135.806 183.324 1.00 91.28  ? 270 LYS R N     1 
ATOM   6393 C CA    . LYS D 4 433 ? 128.885 135.036 182.261 1.00 90.33  ? 270 LYS R CA    1 
ATOM   6394 C C     . LYS D 4 433 ? 127.799 135.849 181.567 1.00 92.59  ? 270 LYS R C     1 
ATOM   6395 O O     . LYS D 4 433 ? 127.695 135.836 180.337 1.00 92.34  ? 270 LYS R O     1 
ATOM   6396 C CB    . LYS D 4 433 ? 128.309 133.738 182.825 1.00 90.73  ? 270 LYS R CB    1 
ATOM   6397 N N     . GLU D 4 434 ? 126.982 136.568 182.342 1.00 94.52  ? 271 GLU R N     1 
ATOM   6398 C CA    . GLU D 4 434 ? 125.945 137.410 181.752 1.00 96.58  ? 271 GLU R CA    1 
ATOM   6399 C C     . GLU D 4 434 ? 126.551 138.541 180.930 1.00 95.01  ? 271 GLU R C     1 
ATOM   6400 O O     . GLU D 4 434 ? 126.063 138.860 179.836 1.00 91.96  ? 271 GLU R O     1 
ATOM   6401 C CB    . GLU D 4 434 ? 125.042 137.968 182.852 1.00 94.09  ? 271 GLU R CB    1 
ATOM   6402 C CG    . GLU D 4 434 ? 123.989 138.947 182.365 1.00 96.48  ? 271 GLU R CG    1 
ATOM   6403 C CD    . GLU D 4 434 ? 123.398 139.771 183.493 1.00 98.54  ? 271 GLU R CD    1 
ATOM   6404 O OE1   . GLU D 4 434 ? 123.077 139.192 184.551 1.00 97.71  ? 271 GLU R OE1   1 
ATOM   6405 O OE2   . GLU D 4 434 ? 123.257 141.000 183.323 1.00 99.27  ? 271 GLU R OE2   1 
ATOM   6406 N N     . ILE D 4 435 ? 127.613 139.165 181.445 1.00 91.04  ? 272 ILE R N     1 
ATOM   6407 C CA    . ILE D 4 435 ? 128.270 140.243 180.707 1.00 89.85  ? 272 ILE R CA    1 
ATOM   6408 C C     . ILE D 4 435 ? 128.842 139.718 179.396 1.00 89.37  ? 272 ILE R C     1 
ATOM   6409 O O     . ILE D 4 435 ? 128.708 140.353 178.342 1.00 93.16  ? 272 ILE R O     1 
ATOM   6410 C CB    . ILE D 4 435 ? 129.354 140.904 181.579 1.00 91.01  ? 272 ILE R CB    1 
ATOM   6411 C CG1   . ILE D 4 435 ? 128.710 141.664 182.740 1.00 89.95  ? 272 ILE R CG1   1 
ATOM   6412 C CG2   . ILE D 4 435 ? 130.219 141.836 180.745 1.00 90.56  ? 272 ILE R CG2   1 
ATOM   6413 C CD1   . ILE D 4 435 ? 127.790 142.781 182.301 1.00 90.13  ? 272 ILE R CD1   1 
ATOM   6414 N N     . LEU D 4 436 ? 129.484 138.548 179.439 1.00 79.66  ? 273 LEU R N     1 
ATOM   6415 C CA    . LEU D 4 436 ? 130.037 137.956 178.228 1.00 79.01  ? 273 LEU R CA    1 
ATOM   6416 C C     . LEU D 4 436 ? 128.936 137.570 177.249 1.00 80.24  ? 273 LEU R C     1 
ATOM   6417 O O     . LEU D 4 436 ? 129.114 137.692 176.034 1.00 81.49  ? 273 LEU R O     1 
ATOM   6418 C CB    . LEU D 4 436 ? 130.895 136.743 178.582 1.00 75.93  ? 273 LEU R CB    1 
ATOM   6419 C CG    . LEU D 4 436 ? 132.273 137.079 179.152 1.00 75.42  ? 273 LEU R CG    1 
ATOM   6420 C CD1   . LEU D 4 436 ? 132.937 135.844 179.738 1.00 77.39  ? 273 LEU R CD1   1 
ATOM   6421 C CD2   . LEU D 4 436 ? 133.148 137.713 178.085 1.00 76.77  ? 273 LEU R CD2   1 
ATOM   6422 N N     . ARG D 4 437 ? 127.796 137.097 177.756 1.00 80.65  ? 274 ARG R N     1 
ATOM   6423 C CA    . ARG D 4 437 ? 126.673 136.774 176.882 1.00 76.10  ? 274 ARG R CA    1 
ATOM   6424 C C     . ARG D 4 437 ? 126.160 138.018 176.168 1.00 82.45  ? 274 ARG R C     1 
ATOM   6425 O O     . ARG D 4 437 ? 125.901 137.993 174.959 1.00 85.77  ? 274 ARG R O     1 
ATOM   6426 C CB    . ARG D 4 437 ? 125.556 136.115 177.691 1.00 76.96  ? 274 ARG R CB    1 
ATOM   6427 C CG    . ARG D 4 437 ? 124.221 136.043 176.969 1.00 80.03  ? 274 ARG R CG    1 
ATOM   6428 C CD    . ARG D 4 437 ? 123.289 135.042 177.630 1.00 84.04  ? 274 ARG R CD    1 
ATOM   6429 N NE    . ARG D 4 437 ? 121.898 135.261 177.251 1.00 87.93  ? 274 ARG R NE    1 
ATOM   6430 C CZ    . ARG D 4 437 ? 121.324 134.743 176.174 1.00 86.18  ? 274 ARG R CZ    1 
ATOM   6431 N NH1   . ARG D 4 437 ? 121.993 133.962 175.342 1.00 85.35  ? 274 ARG R NH1   1 
ATOM   6432 N NH2   . ARG D 4 437 ? 120.046 135.017 175.925 1.00 81.59  ? 274 ARG R NH2   1 
ATOM   6433 N N     . TYR D 4 438 ? 126.011 139.122 176.904 1.00 89.65  ? 275 TYR R N     1 
ATOM   6434 C CA    . TYR D 4 438 ? 125.564 140.365 176.280 1.00 90.50  ? 275 TYR R CA    1 
ATOM   6435 C C     . TYR D 4 438 ? 126.572 140.857 175.248 1.00 85.68  ? 275 TYR R C     1 
ATOM   6436 O O     . TYR D 4 438 ? 126.193 141.298 174.153 1.00 88.49  ? 275 TYR R O     1 
ATOM   6437 C CB    . TYR D 4 438 ? 125.321 141.433 177.346 1.00 87.64  ? 275 TYR R CB    1 
ATOM   6438 C CG    . TYR D 4 438 ? 124.119 141.163 178.221 1.00 87.33  ? 275 TYR R CG    1 
ATOM   6439 C CD1   . TYR D 4 438 ? 123.136 140.266 177.827 1.00 87.86  ? 275 TYR R CD1   1 
ATOM   6440 C CD2   . TYR D 4 438 ? 123.966 141.808 179.440 1.00 88.20  ? 275 TYR R CD2   1 
ATOM   6441 C CE1   . TYR D 4 438 ? 122.036 140.016 178.624 1.00 87.31  ? 275 TYR R CE1   1 
ATOM   6442 C CE2   . TYR D 4 438 ? 122.869 141.566 180.243 1.00 89.55  ? 275 TYR R CE2   1 
ATOM   6443 C CZ    . TYR D 4 438 ? 121.907 140.669 179.830 1.00 89.14  ? 275 TYR R CZ    1 
ATOM   6444 O OH    . TYR D 4 438 ? 120.811 140.422 180.626 1.00 89.49  ? 275 TYR R OH    1 
ATOM   6445 N N     . MET D 4 439 ? 127.864 140.788 175.580 1.00 71.03  ? 276 MET R N     1 
ATOM   6446 C CA    . MET D 4 439 ? 128.893 141.217 174.640 1.00 74.18  ? 276 MET R CA    1 
ATOM   6447 C C     . MET D 4 439 ? 128.889 140.352 173.386 1.00 74.91  ? 276 MET R C     1 
ATOM   6448 O O     . MET D 4 439 ? 129.025 140.865 172.269 1.00 78.05  ? 276 MET R O     1 
ATOM   6449 C CB    . MET D 4 439 ? 130.265 141.186 175.312 1.00 73.55  ? 276 MET R CB    1 
ATOM   6450 C CG    . MET D 4 439 ? 131.399 141.673 174.427 1.00 74.94  ? 276 MET R CG    1 
ATOM   6451 S SD    . MET D 4 439 ? 132.751 142.401 175.370 1.00 83.76  ? 276 MET R SD    1 
ATOM   6452 C CE    . MET D 4 439 ? 133.207 141.026 176.422 1.00 74.36  ? 276 MET R CE    1 
ATOM   6453 N N     . LYS D 4 440 ? 128.730 139.036 173.551 1.00 61.36  ? 277 LYS R N     1 
ATOM   6454 C CA    . LYS D 4 440 ? 128.669 138.149 172.396 1.00 55.47  ? 277 LYS R CA    1 
ATOM   6455 C C     . LYS D 4 440 ? 127.450 138.456 171.544 1.00 56.77  ? 277 LYS R C     1 
ATOM   6456 O O     . LYS D 4 440 ? 127.532 138.439 170.314 1.00 69.91  ? 277 LYS R O     1 
ATOM   6457 C CB    . LYS D 4 440 ? 128.645 136.685 172.839 1.00 60.19  ? 277 LYS R CB    1 
ATOM   6458 C CG    . LYS D 4 440 ? 128.931 135.692 171.710 1.00 59.88  ? 277 LYS R CG    1 
ATOM   6459 C CD    . LYS D 4 440 ? 127.673 135.221 170.980 1.00 57.39  ? 277 LYS R CD    1 
ATOM   6460 C CE    . LYS D 4 440 ? 126.838 134.273 171.815 1.00 63.29  ? 277 LYS R CE    1 
ATOM   6461 N NZ    . LYS D 4 440 ? 125.681 133.733 171.047 1.00 59.63  ? 277 LYS R NZ    1 
ATOM   6462 N N     . GLU D 4 441 ? 126.347 138.775 172.177 1.00 58.28  ? 278 GLU R N     1 
ATOM   6463 C CA    . GLU D 4 441 ? 125.157 139.038 171.419 1.00 64.43  ? 278 GLU R CA    1 
ATOM   6464 C C     . GLU D 4 441 ? 125.297 140.319 170.621 1.00 67.40  ? 278 GLU R C     1 
ATOM   6465 O O     . GLU D 4 441 ? 124.885 140.371 169.476 1.00 68.62  ? 278 GLU R O     1 
ATOM   6466 C CB    . GLU D 4 441 ? 123.974 139.117 172.352 1.00 69.63  ? 278 GLU R CB    1 
ATOM   6467 C CG    . GLU D 4 441 ? 123.513 137.767 172.867 1.00 71.66  ? 278 GLU R CG    1 
ATOM   6468 C CD    . GLU D 4 441 ? 123.293 136.757 171.755 1.00 74.30  ? 278 GLU R CD    1 
ATOM   6469 O OE1   . GLU D 4 441 ? 122.604 137.082 170.764 1.00 74.47  ? 278 GLU R OE1   1 
ATOM   6470 O OE2   . GLU D 4 441 ? 123.801 135.625 171.874 1.00 70.39  ? 278 GLU R OE2   1 
ATOM   6471 N N     . PHE D 4 442 ? 125.887 141.353 171.209 1.00 69.83  ? 279 PHE R N     1 
ATOM   6472 C CA    . PHE D 4 442 ? 126.099 142.603 170.481 1.00 69.86  ? 279 PHE R CA    1 
ATOM   6473 C C     . PHE D 4 442 ? 127.113 142.434 169.351 1.00 66.69  ? 279 PHE R C     1 
ATOM   6474 O O     . PHE D 4 442 ? 126.914 142.949 168.241 1.00 68.10  ? 279 PHE R O     1 
ATOM   6475 C CB    . PHE D 4 442 ? 126.541 143.702 171.446 1.00 69.34  ? 279 PHE R CB    1 
ATOM   6476 C CG    . PHE D 4 442 ? 125.415 144.291 172.245 1.00 70.70  ? 279 PHE R CG    1 
ATOM   6477 C CD1   . PHE D 4 442 ? 124.297 144.808 171.611 1.00 69.08  ? 279 PHE R CD1   1 
ATOM   6478 C CD2   . PHE D 4 442 ? 125.471 144.326 173.628 1.00 71.75  ? 279 PHE R CD2   1 
ATOM   6479 C CE1   . PHE D 4 442 ? 123.257 145.349 172.342 1.00 70.77  ? 279 PHE R CE1   1 
ATOM   6480 C CE2   . PHE D 4 442 ? 124.434 144.866 174.364 1.00 72.12  ? 279 PHE R CE2   1 
ATOM   6481 C CZ    . PHE D 4 442 ? 123.326 145.379 173.720 1.00 72.36  ? 279 PHE R CZ    1 
ATOM   6482 N N     . THR D 4 443 ? 128.205 141.712 169.608 1.00 55.71  ? 280 THR R N     1 
ATOM   6483 C CA    . THR D 4 443 ? 129.215 141.519 168.573 1.00 53.59  ? 280 THR R CA    1 
ATOM   6484 C C     . THR D 4 443 ? 128.689 140.647 167.439 1.00 54.59  ? 280 THR R C     1 
ATOM   6485 O O     . THR D 4 443 ? 129.002 140.885 166.265 1.00 58.66  ? 280 THR R O     1 
ATOM   6486 C CB    . THR D 4 443 ? 130.475 140.914 169.185 1.00 49.85  ? 280 THR R CB    1 
ATOM   6487 O OG1   . THR D 4 443 ? 130.126 139.760 169.958 1.00 63.56  ? 280 THR R OG1   1 
ATOM   6488 C CG2   . THR D 4 443 ? 131.171 141.928 170.080 1.00 46.47  ? 280 THR R CG2   1 
ATOM   6489 N N     . LEU D 4 444 ? 127.887 139.632 167.766 1.00 51.27  ? 281 LEU R N     1 
ATOM   6490 C CA    . LEU D 4 444 ? 127.242 138.832 166.735 1.00 49.45  ? 281 LEU R CA    1 
ATOM   6491 C C     . LEU D 4 444 ? 126.222 139.652 165.963 1.00 64.14  ? 281 LEU R C     1 
ATOM   6492 O O     . LEU D 4 444 ? 126.016 139.415 164.772 1.00 68.23  ? 281 LEU R O     1 
ATOM   6493 C CB    . LEU D 4 444 ? 126.579 137.607 167.362 1.00 53.57  ? 281 LEU R CB    1 
ATOM   6494 C CG    . LEU D 4 444 ? 126.320 136.424 166.432 1.00 56.95  ? 281 LEU R CG    1 
ATOM   6495 C CD1   . LEU D 4 444 ? 127.608 135.660 166.191 1.00 56.18  ? 281 LEU R CD1   1 
ATOM   6496 C CD2   . LEU D 4 444 ? 125.250 135.511 167.008 1.00 62.58  ? 281 LEU R CD2   1 
ATOM   6497 N N     . LEU D 4 445 ? 125.587 140.627 166.615 1.00 69.46  ? 282 LEU R N     1 
ATOM   6498 C CA    . LEU D 4 445 ? 124.705 141.541 165.899 1.00 64.80  ? 282 LEU R CA    1 
ATOM   6499 C C     . LEU D 4 445 ? 125.487 142.400 164.912 1.00 60.77  ? 282 LEU R C     1 
ATOM   6500 O O     . LEU D 4 445 ? 125.003 142.690 163.814 1.00 64.45  ? 282 LEU R O     1 
ATOM   6501 C CB    . LEU D 4 445 ? 123.945 142.412 166.897 1.00 66.28  ? 282 LEU R CB    1 
ATOM   6502 C CG    . LEU D 4 445 ? 122.743 143.202 166.384 1.00 70.04  ? 282 LEU R CG    1 
ATOM   6503 C CD1   . LEU D 4 445 ? 121.699 143.261 167.475 1.00 71.85  ? 282 LEU R CD1   1 
ATOM   6504 C CD2   . LEU D 4 445 ? 123.144 144.605 165.956 1.00 67.42  ? 282 LEU R CD2   1 
ATOM   6505 N N     . LEU D 4 446 ? 126.689 142.834 165.294 1.00 52.77  ? 283 LEU R N     1 
ATOM   6506 C CA    . LEU D 4 446 ? 127.539 143.569 164.356 1.00 52.11  ? 283 LEU R CA    1 
ATOM   6507 C C     . LEU D 4 446 ? 127.951 142.686 163.180 1.00 51.94  ? 283 LEU R C     1 
ATOM   6508 O O     . LEU D 4 446 ? 127.891 143.101 162.012 1.00 59.61  ? 283 LEU R O     1 
ATOM   6509 C CB    . LEU D 4 446 ? 128.771 144.112 165.081 1.00 52.39  ? 283 LEU R CB    1 
ATOM   6510 C CG    . LEU D 4 446 ? 128.732 145.578 165.516 1.00 53.62  ? 283 LEU R CG    1 
ATOM   6511 C CD1   . LEU D 4 446 ? 127.569 145.835 166.461 1.00 58.22  ? 283 LEU R CD1   1 
ATOM   6512 C CD2   . LEU D 4 446 ? 130.048 145.976 166.165 1.00 49.64  ? 283 LEU R CD2   1 
ATOM   6513 N N     . SER D 4 447 ? 128.370 141.454 163.474 1.00 41.12  ? 284 SER R N     1 
ATOM   6514 C CA    . SER D 4 447 ? 128.711 140.516 162.408 1.00 38.03  ? 284 SER R CA    1 
ATOM   6515 C C     . SER D 4 447 ? 127.500 140.200 161.541 1.00 51.13  ? 284 SER R C     1 
ATOM   6516 O O     . SER D 4 447 ? 127.650 139.841 160.368 1.00 52.72  ? 284 SER R O     1 
ATOM   6517 C CB    . SER D 4 447 ? 129.295 139.235 163.002 1.00 45.65  ? 284 SER R CB    1 
ATOM   6518 O OG    . SER D 4 447 ? 130.464 139.508 163.754 1.00 49.38  ? 284 SER R OG    1 
ATOM   6519 N N     . ALA D 4 448 ? 126.298 140.310 162.106 1.00 59.63  ? 285 ALA R N     1 
ATOM   6520 C CA    . ALA D 4 448 ? 125.081 140.188 161.316 1.00 53.01  ? 285 ALA R CA    1 
ATOM   6521 C C     . ALA D 4 448 ? 124.904 141.394 160.405 1.00 57.80  ? 285 ALA R C     1 
ATOM   6522 O O     . ALA D 4 448 ? 124.665 141.244 159.207 1.00 56.14  ? 285 ALA R O     1 
ATOM   6523 C CB    . ALA D 4 448 ? 123.874 140.022 162.238 1.00 50.22  ? 285 ALA R CB    1 
ATOM   6524 N N     . ALA D 4 449 ? 125.065 142.603 160.949 1.00 62.37  ? 286 ALA R N     1 
ATOM   6525 C CA    . ALA D 4 449 ? 124.947 143.814 160.141 1.00 60.18  ? 286 ALA R CA    1 
ATOM   6526 C C     . ALA D 4 449 ? 125.972 143.839 159.018 1.00 59.96  ? 286 ALA R C     1 
ATOM   6527 O O     . ALA D 4 449 ? 125.813 144.596 158.047 1.00 70.06  ? 286 ALA R O     1 
ATOM   6528 C CB    . ALA D 4 449 ? 125.100 145.055 161.020 1.00 63.37  ? 286 ALA R CB    1 
ATOM   6529 N N     . ASN D 4 450 ? 127.026 143.033 159.141 1.00 49.51  ? 287 ASN R N     1 
ATOM   6530 C CA    . ASN D 4 450 ? 127.930 142.841 158.013 1.00 51.02  ? 287 ASN R CA    1 
ATOM   6531 C C     . ASN D 4 450 ? 127.192 142.363 156.763 1.00 52.72  ? 287 ASN R C     1 
ATOM   6532 O O     . ASN D 4 450 ? 127.622 142.670 155.646 1.00 56.72  ? 287 ASN R O     1 
ATOM   6533 C CB    . ASN D 4 450 ? 129.035 141.853 158.377 1.00 58.79  ? 287 ASN R CB    1 
ATOM   6534 C CG    . ASN D 4 450 ? 130.148 141.823 157.347 1.00 52.69  ? 287 ASN R CG    1 
ATOM   6535 O OD1   . ASN D 4 450 ? 130.308 140.845 156.618 1.00 56.85  ? 287 ASN R OD1   1 
ATOM   6536 N ND2   . ASN D 4 450 ? 130.922 142.900 157.280 1.00 48.43  ? 287 ASN R ND2   1 
ATOM   6537 N N     . VAL D 4 451 ? 126.088 141.620 156.913 1.00 57.87  ? 288 VAL R N     1 
ATOM   6538 C CA    . VAL D 4 451 ? 125.386 141.133 155.725 1.00 56.66  ? 288 VAL R CA    1 
ATOM   6539 C C     . VAL D 4 451 ? 124.762 142.299 154.968 1.00 59.03  ? 288 VAL R C     1 
ATOM   6540 O O     . VAL D 4 451 ? 124.689 142.287 153.734 1.00 56.44  ? 288 VAL R O     1 
ATOM   6541 C CB    . VAL D 4 451 ? 124.327 140.064 156.076 1.00 55.29  ? 288 VAL R CB    1 
ATOM   6542 C CG1   . VAL D 4 451 ? 123.152 140.647 156.847 1.00 54.32  ? 288 VAL R CG1   1 
ATOM   6543 C CG2   . VAL D 4 451 ? 123.834 139.382 154.827 1.00 58.55  ? 288 VAL R CG2   1 
ATOM   6544 N N     . CYS D 4 452 ? 124.288 143.316 155.692 1.00 65.59  ? 289 CYS R N     1 
ATOM   6545 C CA    . CYS D 4 452 ? 123.768 144.510 155.036 1.00 62.09  ? 289 CYS R CA    1 
ATOM   6546 C C     . CYS D 4 452 ? 124.897 145.364 154.481 1.00 62.59  ? 289 CYS R C     1 
ATOM   6547 O O     . CYS D 4 452 ? 124.754 145.984 153.421 1.00 65.62  ? 289 CYS R O     1 
ATOM   6548 C CB    . CYS D 4 452 ? 122.921 145.325 156.012 1.00 64.15  ? 289 CYS R CB    1 
ATOM   6549 S SG    . CYS D 4 452 ? 121.280 144.656 156.321 1.00 78.85  ? 289 CYS R SG    1 
ATOM   6550 N N     . LEU D 4 453 ? 126.026 145.416 155.190 1.00 59.66  ? 290 LEU R N     1 
ATOM   6551 C CA    . LEU D 4 453 ? 127.125 146.264 154.743 1.00 53.32  ? 290 LEU R CA    1 
ATOM   6552 C C     . LEU D 4 453 ? 127.868 145.687 153.541 1.00 52.39  ? 290 LEU R C     1 
ATOM   6553 O O     . LEU D 4 453 ? 128.532 146.441 152.823 1.00 57.94  ? 290 LEU R O     1 
ATOM   6554 C CB    . LEU D 4 453 ? 128.096 146.508 155.898 1.00 58.62  ? 290 LEU R CB    1 
ATOM   6555 C CG    . LEU D 4 453 ? 127.497 147.290 157.069 1.00 59.37  ? 290 LEU R CG    1 
ATOM   6556 C CD1   . LEU D 4 453 ? 128.472 147.386 158.231 1.00 56.85  ? 290 LEU R CD1   1 
ATOM   6557 C CD2   . LEU D 4 453 ? 127.064 148.675 156.614 1.00 60.85  ? 290 LEU R CD2   1 
ATOM   6558 N N     . ASP D 4 454 ? 127.777 144.377 153.309 1.00 56.19  ? 291 ASP R N     1 
ATOM   6559 C CA    . ASP D 4 454 ? 128.517 143.765 152.205 1.00 57.39  ? 291 ASP R CA    1 
ATOM   6560 C C     . ASP D 4 454 ? 128.079 144.238 150.822 1.00 61.11  ? 291 ASP R C     1 
ATOM   6561 O O     . ASP D 4 454 ? 128.954 144.621 150.026 1.00 67.77  ? 291 ASP R O     1 
ATOM   6562 C CB    . ASP D 4 454 ? 128.433 142.239 152.315 1.00 54.82  ? 291 ASP R CB    1 
ATOM   6563 C CG    . ASP D 4 454 ? 129.384 141.677 153.351 1.00 66.30  ? 291 ASP R CG    1 
ATOM   6564 O OD1   . ASP D 4 454 ? 130.482 142.248 153.522 1.00 60.02  ? 291 ASP R OD1   1 
ATOM   6565 O OD2   . ASP D 4 454 ? 129.036 140.664 153.993 1.00 62.65  ? 291 ASP R OD2   1 
ATOM   6566 N N     . PRO D 4 455 ? 126.787 144.224 150.453 1.00 57.62  ? 292 PRO R N     1 
ATOM   6567 C CA    . PRO D 4 455 ? 126.436 144.557 149.058 1.00 51.36  ? 292 PRO R CA    1 
ATOM   6568 C C     . PRO D 4 455 ? 126.860 145.949 148.627 1.00 54.35  ? 292 PRO R C     1 
ATOM   6569 O O     . PRO D 4 455 ? 127.251 146.141 147.469 1.00 55.90  ? 292 PRO R O     1 
ATOM   6570 C CB    . PRO D 4 455 ? 124.908 144.401 149.037 1.00 53.63  ? 292 PRO R CB    1 
ATOM   6571 C CG    . PRO D 4 455 ? 124.604 143.486 150.159 1.00 55.52  ? 292 PRO R CG    1 
ATOM   6572 C CD    . PRO D 4 455 ? 125.592 143.840 151.223 1.00 56.14  ? 292 PRO R CD    1 
ATOM   6573 N N     . ILE D 4 456 ? 126.790 146.931 149.526 1.00 54.54  ? 293 ILE R N     1 
ATOM   6574 C CA    . ILE D 4 456 ? 127.197 148.286 149.175 1.00 47.16  ? 293 ILE R CA    1 
ATOM   6575 C C     . ILE D 4 456 ? 128.697 148.342 148.918 1.00 43.77  ? 293 ILE R C     1 
ATOM   6576 O O     . ILE D 4 456 ? 129.166 149.081 148.044 1.00 56.10  ? 293 ILE R O     1 
ATOM   6577 C CB    . ILE D 4 456 ? 126.770 149.271 150.278 1.00 50.85  ? 293 ILE R CB    1 
ATOM   6578 C CG1   . ILE D 4 456 ? 125.260 149.188 150.508 1.00 57.56  ? 293 ILE R CG1   1 
ATOM   6579 C CG2   . ILE D 4 456 ? 127.173 150.692 149.917 1.00 53.05  ? 293 ILE R CG2   1 
ATOM   6580 C CD1   . ILE D 4 456 ? 124.436 149.541 149.289 1.00 56.37  ? 293 ILE R CD1   1 
ATOM   6581 N N     . ILE D 4 457 ? 129.470 147.558 149.662 1.00 42.77  ? 294 ILE R N     1 
ATOM   6582 C CA    . ILE D 4 457 ? 130.925 147.640 149.599 1.00 46.04  ? 294 ILE R CA    1 
ATOM   6583 C C     . ILE D 4 457 ? 131.508 146.636 148.611 1.00 47.69  ? 294 ILE R C     1 
ATOM   6584 O O     . ILE D 4 457 ? 132.449 146.954 147.881 1.00 53.58  ? 294 ILE R O     1 
ATOM   6585 C CB    . ILE D 4 457 ? 131.507 147.453 151.014 1.00 45.88  ? 294 ILE R CB    1 
ATOM   6586 C CG1   . ILE D 4 457 ? 131.008 148.568 151.933 1.00 54.12  ? 294 ILE R CG1   1 
ATOM   6587 C CG2   . ILE D 4 457 ? 133.021 147.446 150.974 1.00 46.82  ? 294 ILE R CG2   1 
ATOM   6588 C CD1   . ILE D 4 457 ? 131.412 148.400 153.375 1.00 57.75  ? 294 ILE R CD1   1 
ATOM   6589 N N     . TYR D 4 458 ? 130.967 145.418 148.557 1.00 43.56  ? 295 TYR R N     1 
ATOM   6590 C CA    . TYR D 4 458 ? 131.527 144.361 147.719 1.00 40.77  ? 295 TYR R CA    1 
ATOM   6591 C C     . TYR D 4 458 ? 130.821 144.242 146.372 1.00 43.56  ? 295 TYR R C     1 
ATOM   6592 O O     . TYR D 4 458 ? 131.462 144.344 145.322 1.00 44.13  ? 295 TYR R O     1 
ATOM   6593 C CB    . TYR D 4 458 ? 131.477 143.019 148.463 1.00 35.08  ? 295 TYR R CB    1 
ATOM   6594 C CG    . TYR D 4 458 ? 132.716 142.724 149.276 1.00 32.20  ? 295 TYR R CG    1 
ATOM   6595 C CD1   . TYR D 4 458 ? 132.853 143.206 150.570 1.00 39.77  ? 295 TYR R CD1   1 
ATOM   6596 C CD2   . TYR D 4 458 ? 133.749 141.964 148.748 1.00 40.38  ? 295 TYR R CD2   1 
ATOM   6597 C CE1   . TYR D 4 458 ? 133.985 142.938 151.315 1.00 41.87  ? 295 TYR R CE1   1 
ATOM   6598 C CE2   . TYR D 4 458 ? 134.884 141.691 149.484 1.00 34.97  ? 295 TYR R CE2   1 
ATOM   6599 C CZ    . TYR D 4 458 ? 134.997 142.180 150.767 1.00 34.98  ? 295 TYR R CZ    1 
ATOM   6600 O OH    . TYR D 4 458 ? 136.126 141.909 151.504 1.00 38.70  ? 295 TYR R OH    1 
ATOM   6601 N N     . PHE D 4 459 ? 129.504 144.025 146.381 1.00 48.24  ? 296 PHE R N     1 
ATOM   6602 C CA    . PHE D 4 459 ? 128.801 143.723 145.137 1.00 44.25  ? 296 PHE R CA    1 
ATOM   6603 C C     . PHE D 4 459 ? 128.632 144.967 144.272 1.00 49.50  ? 296 PHE R C     1 
ATOM   6604 O O     . PHE D 4 459 ? 128.669 144.878 143.040 1.00 48.75  ? 296 PHE R O     1 
ATOM   6605 C CB    . PHE D 4 459 ? 127.441 143.089 145.437 1.00 41.85  ? 296 PHE R CB    1 
ATOM   6606 C CG    . PHE D 4 459 ? 127.510 141.912 146.372 1.00 43.82  ? 296 PHE R CG    1 
ATOM   6607 C CD1   . PHE D 4 459 ? 128.625 141.091 146.400 1.00 47.19  ? 296 PHE R CD1   1 
ATOM   6608 C CD2   . PHE D 4 459 ? 126.455 141.626 147.221 1.00 46.95  ? 296 PHE R CD2   1 
ATOM   6609 C CE1   . PHE D 4 459 ? 128.689 140.014 147.260 1.00 42.73  ? 296 PHE R CE1   1 
ATOM   6610 C CE2   . PHE D 4 459 ? 126.513 140.551 148.084 1.00 50.52  ? 296 PHE R CE2   1 
ATOM   6611 C CZ    . PHE D 4 459 ? 127.632 139.744 148.103 1.00 47.71  ? 296 PHE R CZ    1 
ATOM   6612 N N     . PHE D 4 460 ? 128.447 146.132 144.897 1.00 56.84  ? 297 PHE R N     1 
ATOM   6613 C CA    . PHE D 4 460 ? 128.195 147.351 144.133 1.00 53.41  ? 297 PHE R CA    1 
ATOM   6614 C C     . PHE D 4 460 ? 129.378 147.706 143.241 1.00 59.17  ? 297 PHE R C     1 
ATOM   6615 O O     . PHE D 4 460 ? 129.195 148.129 142.094 1.00 68.27  ? 297 PHE R O     1 
ATOM   6616 C CB    . PHE D 4 460 ? 127.874 148.507 145.081 1.00 55.30  ? 297 PHE R CB    1 
ATOM   6617 N N     . LEU D 4 461 ? 130.601 147.543 143.750 1.00 55.34  ? 298 LEU R N     1 
ATOM   6618 C CA    . LEU D 4 461 ? 131.792 147.876 142.977 1.00 50.87  ? 298 LEU R CA    1 
ATOM   6619 C C     . LEU D 4 461 ? 132.020 146.939 141.799 1.00 50.65  ? 298 LEU R C     1 
ATOM   6620 O O     . LEU D 4 461 ? 132.830 147.263 140.924 1.00 57.65  ? 298 LEU R O     1 
ATOM   6621 C CB    . LEU D 4 461 ? 133.021 147.867 143.885 1.00 52.68  ? 298 LEU R CB    1 
ATOM   6622 C CG    . LEU D 4 461 ? 133.049 148.906 145.005 1.00 54.08  ? 298 LEU R CG    1 
ATOM   6623 C CD1   . LEU D 4 461 ? 134.294 148.731 145.855 1.00 53.55  ? 298 LEU R CD1   1 
ATOM   6624 C CD2   . LEU D 4 461 ? 132.979 150.312 144.431 1.00 53.03  ? 298 LEU R CD2   1 
ATOM   6625 N N     . CYS D 4 462 ? 131.341 145.795 141.755 1.00 53.42  ? 299 CYS R N     1 
ATOM   6626 C CA    . CYS D 4 462 ? 131.507 144.858 140.652 1.00 59.59  ? 299 CYS R CA    1 
ATOM   6627 C C     . CYS D 4 462 ? 130.919 145.452 139.377 1.00 66.05  ? 299 CYS R C     1 
ATOM   6628 O O     . CYS D 4 462 ? 129.729 145.778 139.328 1.00 69.35  ? 299 CYS R O     1 
ATOM   6629 C CB    . CYS D 4 462 ? 130.837 143.529 140.991 1.00 58.82  ? 299 CYS R CB    1 
ATOM   6630 S SG    . CYS D 4 462 ? 130.869 142.306 139.666 1.00 59.06  ? 299 CYS R SG    1 
ATOM   6631 N N     . GLN D 4 463 ? 131.758 145.602 138.350 1.00 72.03  ? 300 GLN R N     1 
ATOM   6632 C CA    . GLN D 4 463 ? 131.309 146.237 137.112 1.00 67.98  ? 300 GLN R CA    1 
ATOM   6633 C C     . GLN D 4 463 ? 130.201 145.459 136.410 1.00 70.95  ? 300 GLN R C     1 
ATOM   6634 O O     . GLN D 4 463 ? 129.184 146.077 136.049 1.00 74.80  ? 300 GLN R O     1 
ATOM   6635 C CB    . GLN D 4 463 ? 132.511 146.468 136.189 1.00 73.18  ? 300 GLN R CB    1 
ATOM   6636 C CG    . GLN D 4 463 ? 132.182 147.206 134.902 1.00 73.23  ? 300 GLN R CG    1 
ATOM   6637 C CD    . GLN D 4 463 ? 131.769 148.644 135.144 1.00 80.43  ? 300 GLN R CD    1 
ATOM   6638 O OE1   . GLN D 4 463 ? 132.353 149.338 135.976 1.00 86.16  ? 300 GLN R OE1   1 
ATOM   6639 N NE2   . GLN D 4 463 ? 130.758 149.101 134.414 1.00 77.37  ? 300 GLN R NE2   1 
ATOM   6640 N N     . PRO D 4 464 ? 130.318 144.144 136.165 1.00 71.64  ? 301 PRO R N     1 
ATOM   6641 C CA    . PRO D 4 464 ? 129.180 143.432 135.555 1.00 73.35  ? 301 PRO R CA    1 
ATOM   6642 C C     . PRO D 4 464 ? 127.913 143.498 136.390 1.00 74.88  ? 301 PRO R C     1 
ATOM   6643 O O     . PRO D 4 464 ? 126.813 143.616 135.833 1.00 79.35  ? 301 PRO R O     1 
ATOM   6644 C CB    . PRO D 4 464 ? 129.700 141.993 135.421 1.00 71.39  ? 301 PRO R CB    1 
ATOM   6645 C CG    . PRO D 4 464 ? 131.175 142.126 135.390 1.00 70.56  ? 301 PRO R CG    1 
ATOM   6646 C CD    . PRO D 4 464 ? 131.486 143.258 136.316 1.00 73.33  ? 301 PRO R CD    1 
ATOM   6647 N N     . PHE D 4 465 ? 128.042 143.433 137.717 1.00 71.42  ? 302 PHE R N     1 
ATOM   6648 C CA    . PHE D 4 465 ? 126.869 143.510 138.582 1.00 67.39  ? 302 PHE R CA    1 
ATOM   6649 C C     . PHE D 4 465 ? 126.169 144.853 138.429 1.00 70.35  ? 302 PHE R C     1 
ATOM   6650 O O     . PHE D 4 465 ? 124.944 144.915 138.284 1.00 77.58  ? 302 PHE R O     1 
ATOM   6651 C CB    . PHE D 4 465 ? 127.278 143.275 140.038 1.00 67.43  ? 302 PHE R CB    1 
ATOM   6652 C CG    . PHE D 4 465 ? 126.152 143.434 141.023 1.00 65.61  ? 302 PHE R CG    1 
ATOM   6653 C CD1   . PHE D 4 465 ? 125.309 142.374 141.305 1.00 66.94  ? 302 PHE R CD1   1 
ATOM   6654 C CD2   . PHE D 4 465 ? 125.940 144.641 141.670 1.00 66.81  ? 302 PHE R CD2   1 
ATOM   6655 C CE1   . PHE D 4 465 ? 124.276 142.513 142.212 1.00 71.11  ? 302 PHE R CE1   1 
ATOM   6656 C CE2   . PHE D 4 465 ? 124.908 144.786 142.576 1.00 71.08  ? 302 PHE R CE2   1 
ATOM   6657 C CZ    . PHE D 4 465 ? 124.075 143.721 142.847 1.00 72.21  ? 302 PHE R CZ    1 
ATOM   6658 N N     . ARG D 4 466 ? 126.940 145.943 138.449 1.00 73.64  ? 303 ARG R N     1 
ATOM   6659 C CA    . ARG D 4 466 ? 126.355 147.270 138.291 1.00 71.60  ? 303 ARG R CA    1 
ATOM   6660 C C     . ARG D 4 466 ? 125.741 147.444 136.908 1.00 76.52  ? 303 ARG R C     1 
ATOM   6661 O O     . ARG D 4 466 ? 124.671 148.048 136.770 1.00 80.03  ? 303 ARG R O     1 
ATOM   6662 C CB    . ARG D 4 466 ? 127.415 148.341 138.549 1.00 70.36  ? 303 ARG R CB    1 
ATOM   6663 C CG    . ARG D 4 466 ? 126.851 149.731 138.788 1.00 73.47  ? 303 ARG R CG    1 
ATOM   6664 C CD    . ARG D 4 466 ? 127.904 150.661 139.368 1.00 73.53  ? 303 ARG R CD    1 
ATOM   6665 N NE    . ARG D 4 466 ? 129.080 150.758 138.512 1.00 77.24  ? 303 ARG R NE    1 
ATOM   6666 C CZ    . ARG D 4 466 ? 130.289 150.329 138.850 1.00 75.02  ? 303 ARG R CZ    1 
ATOM   6667 N NH1   . ARG D 4 466 ? 130.520 149.770 140.026 1.00 72.32  ? 303 ARG R NH1   1 
ATOM   6668 N NH2   . ARG D 4 466 ? 131.291 150.466 137.985 1.00 75.98  ? 303 ARG R NH2   1 
ATOM   6669 N N     . GLU D 4 467 ? 126.403 146.922 135.873 1.00 82.61  ? 304 GLU R N     1 
ATOM   6670 C CA    . GLU D 4 467 ? 125.870 147.035 134.519 1.00 82.99  ? 304 GLU R CA    1 
ATOM   6671 C C     . GLU D 4 467 ? 124.538 146.304 134.391 1.00 82.12  ? 304 GLU R C     1 
ATOM   6672 O O     . GLU D 4 467 ? 123.577 146.835 133.821 1.00 83.88  ? 304 GLU R O     1 
ATOM   6673 C CB    . GLU D 4 467 ? 126.885 146.493 133.512 1.00 79.76  ? 304 GLU R CB    1 
ATOM   6674 C CG    . GLU D 4 467 ? 128.079 147.406 133.290 1.00 82.59  ? 304 GLU R CG    1 
ATOM   6675 C CD    . GLU D 4 467 ? 129.131 146.785 132.393 1.00 82.18  ? 304 GLU R CD    1 
ATOM   6676 O OE1   . GLU D 4 467 ? 129.189 145.540 132.313 1.00 82.94  ? 304 GLU R OE1   1 
ATOM   6677 O OE2   . GLU D 4 467 ? 129.904 147.544 131.770 1.00 81.58  ? 304 GLU R OE2   1 
ATOM   6678 N N     . ILE D 4 468 ? 124.457 145.086 134.930 1.00 72.53  ? 305 ILE R N     1 
ATOM   6679 C CA    . ILE D 4 468 ? 123.212 144.327 134.849 1.00 73.08  ? 305 ILE R CA    1 
ATOM   6680 C C     . ILE D 4 468 ? 122.131 144.977 135.706 1.00 75.43  ? 305 ILE R C     1 
ATOM   6681 O O     . ILE D 4 468 ? 120.952 144.991 135.332 1.00 79.51  ? 305 ILE R O     1 
ATOM   6682 C CB    . ILE D 4 468 ? 123.455 142.855 135.232 1.00 73.93  ? 305 ILE R CB    1 
ATOM   6683 C CG1   . ILE D 4 468 ? 124.167 142.133 134.087 1.00 71.97  ? 305 ILE R CG1   1 
ATOM   6684 C CG2   . ILE D 4 468 ? 122.148 142.152 135.557 1.00 74.40  ? 305 ILE R CG2   1 
ATOM   6685 C CD1   . ILE D 4 468 ? 124.420 140.669 134.345 1.00 68.05  ? 305 ILE R CD1   1 
ATOM   6686 N N     . LEU D 4 469 ? 122.509 145.533 136.861 1.00 81.51  ? 306 LEU R N     1 
ATOM   6687 C CA    . LEU D 4 469 ? 121.545 146.251 137.689 1.00 80.84  ? 306 LEU R CA    1 
ATOM   6688 C C     . LEU D 4 469 ? 120.958 147.437 136.936 1.00 84.92  ? 306 LEU R C     1 
ATOM   6689 O O     . LEU D 4 469 ? 119.742 147.657 136.948 1.00 88.16  ? 306 LEU R O     1 
ATOM   6690 C CB    . LEU D 4 469 ? 122.216 146.713 138.985 1.00 81.80  ? 306 LEU R CB    1 
ATOM   6691 C CG    . LEU D 4 469 ? 121.354 147.396 140.052 1.00 85.77  ? 306 LEU R CG    1 
ATOM   6692 C CD1   . LEU D 4 469 ? 121.796 146.973 141.443 1.00 86.44  ? 306 LEU R CD1   1 
ATOM   6693 C CD2   . LEU D 4 469 ? 121.414 148.912 139.919 1.00 87.72  ? 306 LEU R CD2   1 
ATOM   6694 N N     . CYS D 4 470 ? 121.814 148.213 136.266 1.00 89.10  ? 307 CYS R N     1 
ATOM   6695 C CA    . CYS D 4 470 ? 121.331 149.352 135.494 1.00 90.66  ? 307 CYS R CA    1 
ATOM   6696 C C     . CYS D 4 470 ? 120.452 148.900 134.334 1.00 89.25  ? 307 CYS R C     1 
ATOM   6697 O O     . CYS D 4 470 ? 119.431 149.530 134.036 1.00 89.17  ? 307 CYS R O     1 
ATOM   6698 C CB    . CYS D 4 470 ? 122.511 150.179 134.985 1.00 88.38  ? 307 CYS R CB    1 
ATOM   6699 N N     . LYS D 4 471 ? 120.836 147.811 133.664 1.00 92.36  ? 308 LYS R N     1 
ATOM   6700 C CA    . LYS D 4 471 ? 120.059 147.333 132.523 1.00 92.13  ? 308 LYS R CA    1 
ATOM   6701 C C     . LYS D 4 471 ? 118.686 146.822 132.949 1.00 91.55  ? 308 LYS R C     1 
ATOM   6702 O O     . LYS D 4 471 ? 117.691 147.051 132.252 1.00 93.95  ? 308 LYS R O     1 
ATOM   6703 C CB    . LYS D 4 471 ? 120.831 146.242 131.783 1.00 88.76  ? 308 LYS R CB    1 
ATOM   6704 N N     . LYS D 4 472 ? 118.608 146.133 134.088 1.00 87.35  ? 309 LYS R N     1 
ATOM   6705 C CA    . LYS D 4 472 ? 117.371 145.471 134.489 1.00 88.73  ? 309 LYS R CA    1 
ATOM   6706 C C     . LYS D 4 472 ? 116.449 146.383 135.293 1.00 89.27  ? 309 LYS R C     1 
ATOM   6707 O O     . LYS D 4 472 ? 115.259 146.490 134.982 1.00 91.08  ? 309 LYS R O     1 
ATOM   6708 C CB    . LYS D 4 472 ? 117.694 144.209 135.294 1.00 85.42  ? 309 LYS R CB    1 
ATOM   6709 N N     . LEU D 4 473 ? 116.978 147.037 136.332 1.00 89.68  ? 310 LEU R N     1 
ATOM   6710 C CA    . LEU D 4 473 ? 116.136 147.853 137.202 1.00 91.09  ? 310 LEU R CA    1 
ATOM   6711 C C     . LEU D 4 473 ? 115.546 149.039 136.449 1.00 93.43  ? 310 LEU R C     1 
ATOM   6712 O O     . LEU D 4 473 ? 114.369 149.374 136.628 1.00 91.71  ? 310 LEU R O     1 
ATOM   6713 C CB    . LEU D 4 473 ? 116.944 148.315 138.419 1.00 91.70  ? 310 LEU R CB    1 
ATOM   6714 C CG    . LEU D 4 473 ? 116.251 149.043 139.578 1.00 91.19  ? 310 LEU R CG    1 
ATOM   6715 C CD1   . LEU D 4 473 ? 117.023 148.811 140.865 1.00 90.41  ? 310 LEU R CD1   1 
ATOM   6716 C CD2   . LEU D 4 473 ? 116.121 150.540 139.323 1.00 89.01  ? 310 LEU R CD2   1 
ATOM   6717 N N     . HIS D 4 474 ? 116.341 149.684 135.602 1.00 101.66 ? 311 HIS R N     1 
ATOM   6718 C CA    . HIS D 4 474 ? 115.864 150.832 134.838 1.00 100.70 ? 311 HIS R CA    1 
ATOM   6719 C C     . HIS D 4 474 ? 115.026 150.387 133.644 1.00 98.31  ? 311 HIS R C     1 
ATOM   6720 O O     . HIS D 4 474 ? 115.396 149.458 132.926 1.00 96.22  ? 311 HIS R O     1 
ATOM   6721 C CB    . HIS D 4 474 ? 117.041 151.687 134.368 1.00 98.85  ? 311 HIS R CB    1 
ATOM   6722 C CG    . HIS D 4 474 ? 117.795 152.340 135.483 1.00 101.47 ? 311 HIS R CG    1 
ATOM   6723 N ND1   . HIS D 4 474 ? 117.196 153.187 136.391 1.00 101.66 ? 311 HIS R ND1   1 
ATOM   6724 C CD2   . HIS D 4 474 ? 119.098 152.265 135.842 1.00 102.23 ? 311 HIS R CD2   1 
ATOM   6725 C CE1   . HIS D 4 474 ? 118.098 153.608 137.259 1.00 99.49  ? 311 HIS R CE1   1 
ATOM   6726 N NE2   . HIS D 4 474 ? 119.261 153.064 136.948 1.00 100.74 ? 311 HIS R NE2   1 
ATOM   6727 N N     . ASP E 5 39  ? 151.645 112.185 99.227  1.00 22.14  ? 1   ASP S N     1 
ATOM   6728 C CA    . ASP E 5 39  ? 151.151 113.123 100.227 1.00 23.49  ? 1   ASP S CA    1 
ATOM   6729 C C     . ASP E 5 39  ? 151.183 112.502 101.620 1.00 16.26  ? 1   ASP S C     1 
ATOM   6730 O O     . ASP E 5 39  ? 152.225 112.481 102.275 1.00 14.16  ? 1   ASP S O     1 
ATOM   6731 C CB    . ASP E 5 39  ? 149.730 113.575 99.882  1.00 24.11  ? 1   ASP S CB    1 
ATOM   6732 C CG    . ASP E 5 39  ? 149.416 114.963 100.405 1.00 28.40  ? 1   ASP S CG    1 
ATOM   6733 O OD1   . ASP E 5 39  ? 150.365 115.704 100.734 1.00 27.36  ? 1   ASP S OD1   1 
ATOM   6734 O OD2   . ASP E 5 39  ? 148.220 115.313 100.488 1.00 28.67  ? 1   ASP S OD2   1 
ATOM   6735 N N     . VAL E 5 40  ? 150.032 112.000 102.067 1.00 13.95  ? 2   VAL S N     1 
ATOM   6736 C CA    . VAL E 5 40  ? 149.951 111.346 103.366 1.00 12.97  ? 2   VAL S CA    1 
ATOM   6737 C C     . VAL E 5 40  ? 150.708 110.028 103.313 1.00 11.09  ? 2   VAL S C     1 
ATOM   6738 O O     . VAL E 5 40  ? 150.552 109.240 102.372 1.00 14.63  ? 2   VAL S O     1 
ATOM   6739 C CB    . VAL E 5 40  ? 148.485 111.134 103.771 1.00 3.21   ? 2   VAL S CB    1 
ATOM   6740 C CG1   . VAL E 5 40  ? 148.403 110.384 105.091 1.00 0.09   ? 2   VAL S CG1   1 
ATOM   6741 C CG2   . VAL E 5 40  ? 147.768 112.470 103.866 1.00 6.76   ? 2   VAL S CG2   1 
ATOM   6742 N N     . GLN E 5 41  ? 151.541 109.784 104.323 1.00 4.05   ? 3   GLN S N     1 
ATOM   6743 C CA    . GLN E 5 41  ? 152.381 108.597 104.357 1.00 9.07   ? 3   GLN S CA    1 
ATOM   6744 C C     . GLN E 5 41  ? 152.489 108.084 105.784 1.00 12.78  ? 3   GLN S C     1 
ATOM   6745 O O     . GLN E 5 41  ? 152.765 108.855 106.708 1.00 18.13  ? 3   GLN S O     1 
ATOM   6746 C CB    . GLN E 5 41  ? 153.773 108.898 103.792 1.00 12.62  ? 3   GLN S CB    1 
ATOM   6747 C CG    . GLN E 5 41  ? 154.650 107.677 103.595 1.00 13.65  ? 3   GLN S CG    1 
ATOM   6748 C CD    . GLN E 5 41  ? 156.125 108.003 103.705 1.00 21.45  ? 3   GLN S CD    1 
ATOM   6749 O OE1   . GLN E 5 41  ? 156.580 108.538 104.715 1.00 23.01  ? 3   GLN S OE1   1 
ATOM   6750 N NE2   . GLN E 5 41  ? 156.882 107.682 102.662 1.00 20.14  ? 3   GLN S NE2   1 
ATOM   6751 N N     . LEU E 5 42  ? 152.265 106.782 105.955 1.00 12.56  ? 4   LEU S N     1 
ATOM   6752 C CA    . LEU E 5 42  ? 152.445 106.100 107.231 1.00 13.24  ? 4   LEU S CA    1 
ATOM   6753 C C     . LEU E 5 42  ? 153.372 104.917 107.002 1.00 16.70  ? 4   LEU S C     1 
ATOM   6754 O O     . LEU E 5 42  ? 153.051 104.022 106.215 1.00 19.32  ? 4   LEU S O     1 
ATOM   6755 C CB    . LEU E 5 42  ? 151.106 105.629 107.807 1.00 8.33   ? 4   LEU S CB    1 
ATOM   6756 C CG    . LEU E 5 42  ? 150.148 106.699 108.330 1.00 6.71   ? 4   LEU S CG    1 
ATOM   6757 C CD1   . LEU E 5 42  ? 148.805 106.089 108.687 1.00 0.74   ? 4   LEU S CD1   1 
ATOM   6758 C CD2   . LEU E 5 42  ? 150.746 107.399 109.531 1.00 10.80  ? 4   LEU S CD2   1 
ATOM   6759 N N     . VAL E 5 43  ? 154.516 104.912 107.681 1.00 11.29  ? 5   VAL S N     1 
ATOM   6760 C CA    . VAL E 5 43  ? 155.529 103.877 107.497 1.00 9.44   ? 5   VAL S CA    1 
ATOM   6761 C C     . VAL E 5 43  ? 155.718 103.150 108.820 1.00 20.32  ? 5   VAL S C     1 
ATOM   6762 O O     . VAL E 5 43  ? 156.086 103.767 109.825 1.00 25.39  ? 5   VAL S O     1 
ATOM   6763 C CB    . VAL E 5 43  ? 156.861 104.460 107.001 1.00 15.21  ? 5   VAL S CB    1 
ATOM   6764 C CG1   . VAL E 5 43  ? 157.863 103.346 106.745 1.00 10.23  ? 5   VAL S CG1   1 
ATOM   6765 C CG2   . VAL E 5 43  ? 156.641 105.279 105.743 1.00 18.14  ? 5   VAL S CG2   1 
ATOM   6766 N N     . GLU E 5 44  ? 155.484 101.843 108.815 1.00 19.94  ? 6   GLU S N     1 
ATOM   6767 C CA    . GLU E 5 44  ? 155.643 101.038 110.015 1.00 19.00  ? 6   GLU S CA    1 
ATOM   6768 C C     . GLU E 5 44  ? 157.025 100.393 110.055 1.00 21.71  ? 6   GLU S C     1 
ATOM   6769 O O     . GLU E 5 44  ? 157.669 100.172 109.027 1.00 18.43  ? 6   GLU S O     1 
ATOM   6770 C CB    . GLU E 5 44  ? 154.564 99.958  110.095 1.00 16.25  ? 6   GLU S CB    1 
ATOM   6771 C CG    . GLU E 5 44  ? 153.162 100.472 110.363 1.00 13.91  ? 6   GLU S CG    1 
ATOM   6772 C CD    . GLU E 5 44  ? 152.377 100.699 109.089 1.00 15.54  ? 6   GLU S CD    1 
ATOM   6773 O OE1   . GLU E 5 44  ? 153.006 100.874 108.026 1.00 26.52  ? 6   GLU S OE1   1 
ATOM   6774 O OE2   . GLU E 5 44  ? 151.131 100.680 109.146 1.00 10.05  ? 6   GLU S OE2   1 
ATOM   6775 N N     . SER E 5 45  ? 157.471 100.088 111.270 1.00 19.43  ? 7   SER S N     1 
ATOM   6776 C CA    . SER E 5 45  ? 158.764 99.455  111.490 1.00 18.94  ? 7   SER S CA    1 
ATOM   6777 C C     . SER E 5 45  ? 158.736 98.736  112.830 1.00 24.14  ? 7   SER S C     1 
ATOM   6778 O O     . SER E 5 45  ? 157.900 99.021  113.692 1.00 31.23  ? 7   SER S O     1 
ATOM   6779 C CB    . SER E 5 45  ? 159.905 100.476 111.449 1.00 20.58  ? 7   SER S CB    1 
ATOM   6780 N N     . GLY E 5 46  ? 159.674 97.807  112.997 1.00 24.82  ? 8   GLY S N     1 
ATOM   6781 C CA    . GLY E 5 46  ? 159.799 97.044  114.220 1.00 17.51  ? 8   GLY S CA    1 
ATOM   6782 C C     . GLY E 5 46  ? 159.291 95.620  114.156 1.00 19.47  ? 8   GLY S C     1 
ATOM   6783 O O     . GLY E 5 46  ? 159.294 94.936  115.187 1.00 27.03  ? 8   GLY S O     1 
ATOM   6784 N N     . GLY E 5 47  ? 158.853 95.152  112.989 1.00 23.88  ? 9   GLY S N     1 
ATOM   6785 C CA    . GLY E 5 47  ? 158.408 93.782  112.857 1.00 26.87  ? 9   GLY S CA    1 
ATOM   6786 C C     . GLY E 5 47  ? 159.559 92.810  112.681 1.00 27.86  ? 9   GLY S C     1 
ATOM   6787 O O     . GLY E 5 47  ? 160.716 93.192  112.504 1.00 29.94  ? 9   GLY S O     1 
ATOM   6788 N N     . GLY E 5 48  ? 159.227 91.527  112.733 1.00 27.21  ? 10  GLY S N     1 
ATOM   6789 C CA    . GLY E 5 48  ? 160.207 90.479  112.561 1.00 27.97  ? 10  GLY S CA    1 
ATOM   6790 C C     . GLY E 5 48  ? 159.896 89.298  113.453 1.00 31.95  ? 10  GLY S C     1 
ATOM   6791 O O     . GLY E 5 48  ? 158.748 89.073  113.833 1.00 32.79  ? 10  GLY S O     1 
ATOM   6792 N N     . LEU E 5 49  ? 160.944 88.542  113.776 1.00 32.65  ? 11  LEU S N     1 
ATOM   6793 C CA    . LEU E 5 49  ? 160.827 87.337  114.588 1.00 34.77  ? 11  LEU S CA    1 
ATOM   6794 C C     . LEU E 5 49  ? 160.912 87.691  116.067 1.00 34.13  ? 11  LEU S C     1 
ATOM   6795 O O     . LEU E 5 49  ? 161.845 88.380  116.493 1.00 36.03  ? 11  LEU S O     1 
ATOM   6796 C CB    . LEU E 5 49  ? 161.929 86.338  114.231 1.00 32.64  ? 11  LEU S CB    1 
ATOM   6797 C CG    . LEU E 5 49  ? 161.662 85.269  113.167 1.00 34.53  ? 11  LEU S CG    1 
ATOM   6798 C CD1   . LEU E 5 49  ? 160.576 84.306  113.628 1.00 32.41  ? 11  LEU S CD1   1 
ATOM   6799 C CD2   . LEU E 5 49  ? 161.311 85.893  111.823 1.00 32.96  ? 11  LEU S CD2   1 
ATOM   6800 N N     . VAL E 5 50  ? 159.940 87.220  116.845 1.00 34.67  ? 12  VAL S N     1 
ATOM   6801 C CA    . VAL E 5 50  ? 159.935 87.393  118.293 1.00 36.73  ? 12  VAL S CA    1 
ATOM   6802 C C     . VAL E 5 50  ? 159.634 86.048  118.938 1.00 37.16  ? 12  VAL S C     1 
ATOM   6803 O O     . VAL E 5 50  ? 158.675 85.371  118.552 1.00 39.65  ? 12  VAL S O     1 
ATOM   6804 C CB    . VAL E 5 50  ? 158.910 88.451  118.745 1.00 35.89  ? 12  VAL S CB    1 
ATOM   6805 C CG1   . VAL E 5 50  ? 158.785 88.458  120.258 1.00 35.69  ? 12  VAL S CG1   1 
ATOM   6806 C CG2   . VAL E 5 50  ? 159.320 89.821  118.251 1.00 35.24  ? 12  VAL S CG2   1 
ATOM   6807 N N     . GLN E 5 51  ? 160.452 85.661  119.912 1.00 38.66  ? 13  GLN S N     1 
ATOM   6808 C CA    . GLN E 5 51  ? 160.192 84.439  120.653 1.00 41.44  ? 13  GLN S CA    1 
ATOM   6809 C C     . GLN E 5 51  ? 158.948 84.610  121.524 1.00 42.99  ? 13  GLN S C     1 
ATOM   6810 O O     . GLN E 5 51  ? 158.639 85.720  121.966 1.00 41.94  ? 13  GLN S O     1 
ATOM   6811 C CB    . GLN E 5 51  ? 161.392 84.073  121.521 1.00 41.52  ? 13  GLN S CB    1 
ATOM   6812 C CG    . GLN E 5 51  ? 162.662 83.789  120.736 1.00 43.65  ? 13  GLN S CG    1 
ATOM   6813 C CD    . GLN E 5 51  ? 162.629 82.443  120.039 1.00 45.69  ? 13  GLN S CD    1 
ATOM   6814 O OE1   . GLN E 5 51  ? 161.767 81.608  120.315 1.00 48.04  ? 13  GLN S OE1   1 
ATOM   6815 N NE2   . GLN E 5 51  ? 163.571 82.226  119.129 1.00 42.67  ? 13  GLN S NE2   1 
ATOM   6816 N N     . PRO E 5 52  ? 158.207 83.529  121.771 1.00 42.70  ? 14  PRO S N     1 
ATOM   6817 C CA    . PRO E 5 52  ? 157.010 83.637  122.614 1.00 39.77  ? 14  PRO S CA    1 
ATOM   6818 C C     . PRO E 5 52  ? 157.352 84.157  124.002 1.00 39.12  ? 14  PRO S C     1 
ATOM   6819 O O     . PRO E 5 52  ? 158.376 83.799  124.587 1.00 37.60  ? 14  PRO S O     1 
ATOM   6820 C CB    . PRO E 5 52  ? 156.481 82.200  122.665 1.00 38.45  ? 14  PRO S CB    1 
ATOM   6821 C CG    . PRO E 5 52  ? 157.024 81.554  121.437 1.00 40.94  ? 14  PRO S CG    1 
ATOM   6822 C CD    . PRO E 5 52  ? 158.369 82.178  121.209 1.00 40.91  ? 14  PRO S CD    1 
ATOM   6823 N N     . GLY E 5 53  ? 156.477 85.012  124.526 1.00 33.77  ? 15  GLY S N     1 
ATOM   6824 C CA    . GLY E 5 53  ? 156.703 85.653  125.803 1.00 35.80  ? 15  GLY S CA    1 
ATOM   6825 C C     . GLY E 5 53  ? 157.596 86.872  125.759 1.00 34.41  ? 15  GLY S C     1 
ATOM   6826 O O     . GLY E 5 53  ? 157.858 87.465  126.814 1.00 36.33  ? 15  GLY S O     1 
ATOM   6827 N N     . GLY E 5 54  ? 158.074 87.268  124.580 1.00 28.94  ? 16  GLY S N     1 
ATOM   6828 C CA    . GLY E 5 54  ? 158.952 88.408  124.443 1.00 30.33  ? 16  GLY S CA    1 
ATOM   6829 C C     . GLY E 5 54  ? 158.191 89.714  124.325 1.00 35.07  ? 16  GLY S C     1 
ATOM   6830 O O     . GLY E 5 54  ? 156.970 89.781  124.476 1.00 42.45  ? 16  GLY S O     1 
ATOM   6831 N N     . SER E 5 55  ? 158.944 90.776  124.048 1.00 24.19  ? 17  SER S N     1 
ATOM   6832 C CA    . SER E 5 55  ? 158.379 92.106  123.880 1.00 24.22  ? 17  SER S CA    1 
ATOM   6833 C C     . SER E 5 55  ? 158.971 92.749  122.637 1.00 31.16  ? 17  SER S C     1 
ATOM   6834 O O     . SER E 5 55  ? 160.166 92.601  122.364 1.00 30.30  ? 17  SER S O     1 
ATOM   6835 C CB    . SER E 5 55  ? 158.650 92.984  125.109 1.00 27.06  ? 17  SER S CB    1 
ATOM   6836 O OG    . SER E 5 55  ? 158.212 92.348  126.298 1.00 27.06  ? 17  SER S OG    1 
ATOM   6837 N N     . ARG E 5 56  ? 158.134 93.462  121.887 1.00 30.82  ? 18  ARG S N     1 
ATOM   6838 C CA    . ARG E 5 56  ? 158.586 94.188  120.709 1.00 19.12  ? 18  ARG S CA    1 
ATOM   6839 C C     . ARG E 5 56  ? 157.877 95.532  120.636 1.00 18.13  ? 18  ARG S C     1 
ATOM   6840 O O     . ARG E 5 56  ? 156.750 95.688  121.111 1.00 26.29  ? 18  ARG S O     1 
ATOM   6841 C CB    . ARG E 5 56  ? 158.357 93.392  119.419 1.00 24.82  ? 18  ARG S CB    1 
ATOM   6842 C CG    . ARG E 5 56  ? 159.294 93.797  118.287 1.00 24.72  ? 18  ARG S CG    1 
ATOM   6843 C CD    . ARG E 5 56  ? 160.665 93.152  118.435 1.00 27.86  ? 18  ARG S CD    1 
ATOM   6844 N NE    . ARG E 5 56  ? 161.523 93.387  117.279 1.00 28.00  ? 18  ARG S NE    1 
ATOM   6845 C CZ    . ARG E 5 56  ? 161.395 92.774  116.110 1.00 30.19  ? 18  ARG S CZ    1 
ATOM   6846 N NH1   . ARG E 5 56  ? 160.443 91.880  115.898 1.00 26.82  ? 18  ARG S NH1   1 
ATOM   6847 N NH2   . ARG E 5 56  ? 162.246 93.062  115.130 1.00 27.00  ? 18  ARG S NH2   1 
ATOM   6848 N N     . LYS E 5 57  ? 158.555 96.502  120.032 1.00 19.32  ? 19  LYS S N     1 
ATOM   6849 C CA    . LYS E 5 57  ? 158.126 97.898  120.018 1.00 16.05  ? 19  LYS S CA    1 
ATOM   6850 C C     . LYS E 5 57  ? 157.916 98.323  118.566 1.00 17.70  ? 19  LYS S C     1 
ATOM   6851 O O     . LYS E 5 57  ? 158.872 98.660  117.862 1.00 16.60  ? 19  LYS S O     1 
ATOM   6852 C CB    . LYS E 5 57  ? 159.168 98.766  120.717 1.00 16.83  ? 19  LYS S CB    1 
ATOM   6853 C CG    . LYS E 5 57  ? 158.833 100.239 120.830 1.00 16.52  ? 19  LYS S CG    1 
ATOM   6854 C CD    . LYS E 5 57  ? 157.652 100.464 121.760 1.00 14.21  ? 19  LYS S CD    1 
ATOM   6855 C CE    . LYS E 5 57  ? 157.316 101.934 121.868 1.00 15.36  ? 19  LYS S CE    1 
ATOM   6856 N NZ    . LYS E 5 57  ? 158.406 102.700 122.539 1.00 16.07  ? 19  LYS S NZ    1 
ATOM   6857 N N     . LEU E 5 58  ? 156.662 98.298  118.118 1.00 17.03  ? 20  LEU S N     1 
ATOM   6858 C CA    . LEU E 5 58  ? 156.325 98.732  116.771 1.00 15.36  ? 20  LEU S CA    1 
ATOM   6859 C C     . LEU E 5 58  ? 156.198 100.248 116.716 1.00 17.38  ? 20  LEU S C     1 
ATOM   6860 O O     . LEU E 5 58  ? 155.614 100.872 117.607 1.00 21.68  ? 20  LEU S O     1 
ATOM   6861 C CB    . LEU E 5 58  ? 155.016 98.091  116.309 1.00 7.54   ? 20  LEU S CB    1 
ATOM   6862 C CG    . LEU E 5 58  ? 154.938 96.565  116.359 1.00 13.46  ? 20  LEU S CG    1 
ATOM   6863 C CD1   . LEU E 5 58  ? 153.619 96.068  115.795 1.00 13.01  ? 20  LEU S CD1   1 
ATOM   6864 C CD2   . LEU E 5 58  ? 156.100 95.938  115.617 1.00 14.93  ? 20  LEU S CD2   1 
ATOM   6865 N N     . SER E 5 59  ? 156.733 100.836 115.650 1.00 15.84  ? 21  SER S N     1 
ATOM   6866 C CA    . SER E 5 59  ? 156.675 102.273 115.439 1.00 9.59   ? 21  SER S CA    1 
ATOM   6867 C C     . SER E 5 59  ? 156.025 102.574 114.096 1.00 22.12  ? 21  SER S C     1 
ATOM   6868 O O     . SER E 5 59  ? 156.119 101.789 113.150 1.00 21.42  ? 21  SER S O     1 
ATOM   6869 C CB    . SER E 5 59  ? 158.074 102.899 115.500 1.00 14.53  ? 21  SER S CB    1 
ATOM   6870 N N     . CYS E 5 60  ? 155.344 103.715 114.031 1.00 20.64  ? 22  CYS S N     1 
ATOM   6871 C CA    . CYS E 5 60  ? 154.680 104.169 112.813 1.00 11.18  ? 22  CYS S CA    1 
ATOM   6872 C C     . CYS E 5 60  ? 155.012 105.643 112.637 1.00 17.18  ? 22  CYS S C     1 
ATOM   6873 O O     . CYS E 5 60  ? 154.514 106.487 113.389 1.00 19.97  ? 22  CYS S O     1 
ATOM   6874 C CB    . CYS E 5 60  ? 153.167 103.949 112.881 1.00 10.74  ? 22  CYS S CB    1 
ATOM   6875 S SG    . CYS E 5 60  ? 152.227 104.763 111.560 1.00 44.92  ? 22  CYS S SG    1 
ATOM   6876 N N     . SER E 5 61  ? 155.873 105.941 111.669 1.00 21.04  ? 23  SER S N     1 
ATOM   6877 C CA    . SER E 5 61  ? 156.218 107.315 111.340 1.00 18.32  ? 23  SER S CA    1 
ATOM   6878 C C     . SER E 5 61  ? 155.169 107.897 110.402 1.00 21.80  ? 23  SER S C     1 
ATOM   6879 O O     . SER E 5 61  ? 154.783 107.262 109.414 1.00 27.02  ? 23  SER S O     1 
ATOM   6880 C CB    . SER E 5 61  ? 157.602 107.380 110.694 1.00 16.65  ? 23  SER S CB    1 
ATOM   6881 O OG    . SER E 5 61  ? 158.600 106.876 111.564 1.00 24.02  ? 23  SER S OG    1 
ATOM   6882 N N     . ALA E 5 62  ? 154.717 109.107 110.713 1.00 13.30  ? 24  ALA S N     1 
ATOM   6883 C CA    . ALA E 5 62  ? 153.669 109.783 109.964 1.00 4.75   ? 24  ALA S CA    1 
ATOM   6884 C C     . ALA E 5 62  ? 154.235 111.008 109.261 1.00 12.29  ? 24  ALA S C     1 
ATOM   6885 O O     . ALA E 5 62  ? 155.076 111.721 109.816 1.00 18.14  ? 24  ALA S O     1 
ATOM   6886 C CB    . ALA E 5 62  ? 152.525 110.200 110.888 1.00 7.07   ? 24  ALA S CB    1 
ATOM   6887 N N     . SER E 5 63  ? 153.768 111.249 108.038 1.00 9.39   ? 25  SER S N     1 
ATOM   6888 C CA    . SER E 5 63  ? 154.176 112.429 107.293 1.00 13.18  ? 25  SER S CA    1 
ATOM   6889 C C     . SER E 5 63  ? 153.045 112.845 106.365 1.00 13.29  ? 25  SER S C     1 
ATOM   6890 O O     . SER E 5 63  ? 152.177 112.043 106.013 1.00 18.02  ? 25  SER S O     1 
ATOM   6891 C CB    . SER E 5 63  ? 155.462 112.179 106.497 1.00 16.98  ? 25  SER S CB    1 
ATOM   6892 O OG    . SER E 5 63  ? 155.189 111.498 105.285 1.00 23.20  ? 25  SER S OG    1 
ATOM   6893 N N     . GLY E 5 64  ? 153.062 114.117 105.978 1.00 6.26   ? 26  GLY S N     1 
ATOM   6894 C CA    . GLY E 5 64  ? 152.079 114.633 105.050 1.00 13.49  ? 26  GLY S CA    1 
ATOM   6895 C C     . GLY E 5 64  ? 150.745 115.007 105.651 1.00 10.41  ? 26  GLY S C     1 
ATOM   6896 O O     . GLY E 5 64  ? 149.829 115.364 104.901 1.00 16.31  ? 26  GLY S O     1 
ATOM   6897 N N     . PHE E 5 65  ? 150.597 114.939 106.971 1.00 4.61   ? 27  PHE S N     1 
ATOM   6898 C CA    . PHE E 5 65  ? 149.344 115.323 107.607 1.00 9.96   ? 27  PHE S CA    1 
ATOM   6899 C C     . PHE E 5 65  ? 149.616 115.709 109.053 1.00 9.21   ? 27  PHE S C     1 
ATOM   6900 O O     . PHE E 5 65  ? 150.665 115.388 109.616 1.00 7.48   ? 27  PHE S O     1 
ATOM   6901 C CB    . PHE E 5 65  ? 148.300 114.202 107.518 1.00 7.48   ? 27  PHE S CB    1 
ATOM   6902 C CG    . PHE E 5 65  ? 148.596 113.014 108.389 1.00 9.75   ? 27  PHE S CG    1 
ATOM   6903 C CD1   . PHE E 5 65  ? 149.531 112.070 108.003 1.00 6.85   ? 27  PHE S CD1   1 
ATOM   6904 C CD2   . PHE E 5 65  ? 147.922 112.831 109.584 1.00 0.00   ? 27  PHE S CD2   1 
ATOM   6905 C CE1   . PHE E 5 65  ? 149.796 110.974 108.798 1.00 0.00   ? 27  PHE S CE1   1 
ATOM   6906 C CE2   . PHE E 5 65  ? 148.183 111.737 110.383 1.00 0.84   ? 27  PHE S CE2   1 
ATOM   6907 C CZ    . PHE E 5 65  ? 149.121 110.808 109.989 1.00 4.98   ? 27  PHE S CZ    1 
ATOM   6908 N N     . ALA E 5 66  ? 148.648 116.412 109.645 1.00 5.79   ? 28  ALA S N     1 
ATOM   6909 C CA    . ALA E 5 66  ? 148.766 116.926 111.010 1.00 0.00   ? 28  ALA S CA    1 
ATOM   6910 C C     . ALA E 5 66  ? 148.507 115.785 111.989 1.00 7.60   ? 28  ALA S C     1 
ATOM   6911 O O     . ALA E 5 66  ? 147.399 115.588 112.491 1.00 19.98  ? 28  ALA S O     1 
ATOM   6912 C CB    . ALA E 5 66  ? 147.805 118.086 111.231 1.00 0.71   ? 28  ALA S CB    1 
ATOM   6913 N N     . PHE E 5 67  ? 149.576 115.039 112.284 1.00 4.60   ? 29  PHE S N     1 
ATOM   6914 C CA    . PHE E 5 67  ? 149.463 113.819 113.078 1.00 0.97   ? 29  PHE S CA    1 
ATOM   6915 C C     . PHE E 5 67  ? 148.827 114.065 114.441 1.00 5.14   ? 29  PHE S C     1 
ATOM   6916 O O     . PHE E 5 67  ? 148.132 113.189 114.968 1.00 9.09   ? 29  PHE S O     1 
ATOM   6917 C CB    . PHE E 5 67  ? 150.849 113.190 113.247 1.00 1.78   ? 29  PHE S CB    1 
ATOM   6918 C CG    . PHE E 5 67  ? 150.879 112.011 114.178 1.00 4.16   ? 29  PHE S CG    1 
ATOM   6919 C CD1   . PHE E 5 67  ? 150.509 110.754 113.735 1.00 4.93   ? 29  PHE S CD1   1 
ATOM   6920 C CD2   . PHE E 5 67  ? 151.289 112.158 115.493 1.00 3.13   ? 29  PHE S CD2   1 
ATOM   6921 C CE1   . PHE E 5 67  ? 150.542 109.668 114.585 1.00 6.96   ? 29  PHE S CE1   1 
ATOM   6922 C CE2   . PHE E 5 67  ? 151.320 111.076 116.348 1.00 8.03   ? 29  PHE S CE2   1 
ATOM   6923 C CZ    . PHE E 5 67  ? 150.946 109.830 115.893 1.00 13.08  ? 29  PHE S CZ    1 
ATOM   6924 N N     . SER E 5 68  ? 149.047 115.244 115.027 1.00 4.25   ? 30  SER S N     1 
ATOM   6925 C CA    . SER E 5 68  ? 148.552 115.505 116.375 1.00 3.42   ? 30  SER S CA    1 
ATOM   6926 C C     . SER E 5 68  ? 147.030 115.574 116.427 1.00 8.33   ? 30  SER S C     1 
ATOM   6927 O O     . SER E 5 68  ? 146.436 115.287 117.472 1.00 17.58  ? 30  SER S O     1 
ATOM   6928 C CB    . SER E 5 68  ? 149.155 116.801 116.913 1.00 6.24   ? 30  SER S CB    1 
ATOM   6929 O OG    . SER E 5 68  ? 148.448 117.929 116.428 1.00 12.12  ? 30  SER S OG    1 
ATOM   6930 N N     . SER E 5 69  ? 146.385 115.948 115.325 1.00 7.95   ? 31  SER S N     1 
ATOM   6931 C CA    . SER E 5 69  ? 144.942 116.145 115.301 1.00 0.25   ? 31  SER S CA    1 
ATOM   6932 C C     . SER E 5 69  ? 144.170 114.894 114.905 1.00 4.33   ? 31  SER S C     1 
ATOM   6933 O O     . SER E 5 69  ? 142.942 114.954 114.791 1.00 10.03  ? 31  SER S O     1 
ATOM   6934 C CB    . SER E 5 69  ? 144.584 117.290 114.347 1.00 0.00   ? 31  SER S CB    1 
ATOM   6935 O OG    . SER E 5 69  ? 144.835 116.928 113.001 1.00 11.83  ? 31  SER S OG    1 
ATOM   6936 N N     . PHE E 5 70  ? 144.847 113.770 114.697 1.00 4.35   ? 32  PHE S N     1 
ATOM   6937 C CA    . PHE E 5 70  ? 144.210 112.535 114.266 1.00 0.00   ? 32  PHE S CA    1 
ATOM   6938 C C     . PHE E 5 70  ? 144.299 111.476 115.354 1.00 1.57   ? 32  PHE S C     1 
ATOM   6939 O O     . PHE E 5 70  ? 145.328 111.342 116.022 1.00 14.93  ? 32  PHE S O     1 
ATOM   6940 C CB    . PHE E 5 70  ? 144.860 111.995 112.991 1.00 0.00   ? 32  PHE S CB    1 
ATOM   6941 C CG    . PHE E 5 70  ? 144.531 112.780 111.761 1.00 4.23   ? 32  PHE S CG    1 
ATOM   6942 C CD1   . PHE E 5 70  ? 145.277 113.886 111.410 1.00 6.92   ? 32  PHE S CD1   1 
ATOM   6943 C CD2   . PHE E 5 70  ? 143.481 112.407 110.950 1.00 0.00   ? 32  PHE S CD2   1 
ATOM   6944 C CE1   . PHE E 5 70  ? 144.978 114.606 110.277 1.00 3.46   ? 32  PHE S CE1   1 
ATOM   6945 C CE2   . PHE E 5 70  ? 143.179 113.123 109.814 1.00 0.00   ? 32  PHE S CE2   1 
ATOM   6946 C CZ    . PHE E 5 70  ? 143.929 114.222 109.479 1.00 1.47   ? 32  PHE S CZ    1 
ATOM   6947 N N     . GLY E 5 71  ? 143.214 110.729 115.528 1.00 2.95   ? 33  GLY S N     1 
ATOM   6948 C CA    . GLY E 5 71  ? 143.293 109.488 116.268 1.00 0.00   ? 33  GLY S CA    1 
ATOM   6949 C C     . GLY E 5 71  ? 144.008 108.419 115.465 1.00 0.00   ? 33  GLY S C     1 
ATOM   6950 O O     . GLY E 5 71  ? 143.986 108.407 114.233 1.00 11.45  ? 33  GLY S O     1 
ATOM   6951 N N     . MET E 5 72  ? 144.668 107.511 116.174 1.00 0.00   ? 34  MET S N     1 
ATOM   6952 C CA    . MET E 5 72  ? 145.489 106.496 115.530 1.00 0.00   ? 34  MET S CA    1 
ATOM   6953 C C     . MET E 5 72  ? 145.088 105.118 116.027 1.00 0.00   ? 34  MET S C     1 
ATOM   6954 O O     . MET E 5 72  ? 144.997 104.893 117.237 1.00 0.00   ? 34  MET S O     1 
ATOM   6955 C CB    . MET E 5 72  ? 146.975 106.745 115.791 1.00 0.84   ? 34  MET S CB    1 
ATOM   6956 C CG    . MET E 5 72  ? 147.475 108.087 115.288 1.00 2.24   ? 34  MET S CG    1 
ATOM   6957 S SD    . MET E 5 72  ? 147.273 108.287 113.508 1.00 20.09  ? 34  MET S SD    1 
ATOM   6958 C CE    . MET E 5 72  ? 148.209 106.887 112.902 1.00 0.00   ? 34  MET S CE    1 
ATOM   6959 N N     . HIS E 5 73  ? 144.864 104.200 115.094 1.00 1.87   ? 35  HIS S N     1 
ATOM   6960 C CA    . HIS E 5 73  ? 144.514 102.828 115.416 1.00 0.00   ? 35  HIS S CA    1 
ATOM   6961 C C     . HIS E 5 73  ? 145.655 101.896 115.035 1.00 0.00   ? 35  HIS S C     1 
ATOM   6962 O O     . HIS E 5 73  ? 146.402 102.145 114.090 1.00 0.00   ? 35  HIS S O     1 
ATOM   6963 C CB    . HIS E 5 73  ? 143.236 102.384 114.690 1.00 0.00   ? 35  HIS S CB    1 
ATOM   6964 C CG    . HIS E 5 73  ? 142.031 103.211 115.014 1.00 0.00   ? 35  HIS S CG    1 
ATOM   6965 N ND1   . HIS E 5 73  ? 140.993 102.740 115.788 1.00 0.00   ? 35  HIS S ND1   1 
ATOM   6966 C CD2   . HIS E 5 73  ? 141.692 104.471 114.656 1.00 0.00   ? 35  HIS S CD2   1 
ATOM   6967 C CE1   . HIS E 5 73  ? 140.069 103.677 115.899 1.00 0.00   ? 35  HIS S CE1   1 
ATOM   6968 N NE2   . HIS E 5 73  ? 140.469 104.738 115.222 1.00 0.00   ? 35  HIS S NE2   1 
ATOM   6969 N N     . TRP E 5 74  ? 145.788 100.820 115.798 1.00 2.17   ? 36  TRP S N     1 
ATOM   6970 C CA    . TRP E 5 74  ? 146.588 99.668  115.413 1.00 0.00   ? 36  TRP S CA    1 
ATOM   6971 C C     . TRP E 5 74  ? 145.632 98.537  115.077 1.00 0.00   ? 36  TRP S C     1 
ATOM   6972 O O     . TRP E 5 74  ? 144.763 98.198  115.891 1.00 0.51   ? 36  TRP S O     1 
ATOM   6973 C CB    . TRP E 5 74  ? 147.545 99.245  116.528 1.00 0.63   ? 36  TRP S CB    1 
ATOM   6974 C CG    . TRP E 5 74  ? 148.786 100.070 116.606 1.00 0.00   ? 36  TRP S CG    1 
ATOM   6975 C CD1   . TRP E 5 74  ? 149.079 101.023 117.534 1.00 3.00   ? 36  TRP S CD1   1 
ATOM   6976 C CD2   . TRP E 5 74  ? 149.909 100.016 115.719 1.00 0.00   ? 36  TRP S CD2   1 
ATOM   6977 N NE1   . TRP E 5 74  ? 150.314 101.566 117.282 1.00 4.93   ? 36  TRP S NE1   1 
ATOM   6978 C CE2   . TRP E 5 74  ? 150.844 100.966 116.171 1.00 0.00   ? 36  TRP S CE2   1 
ATOM   6979 C CE3   . TRP E 5 74  ? 150.214 99.257  114.586 1.00 6.60   ? 36  TRP S CE3   1 
ATOM   6980 C CZ2   . TRP E 5 74  ? 152.063 101.176 115.532 1.00 0.00   ? 36  TRP S CZ2   1 
ATOM   6981 C CZ3   . TRP E 5 74  ? 151.424 99.468  113.953 1.00 9.99   ? 36  TRP S CZ3   1 
ATOM   6982 C CH2   . TRP E 5 74  ? 152.333 100.419 114.427 1.00 7.69   ? 36  TRP S CH2   1 
ATOM   6983 N N     . VAL E 5 75  ? 145.787 97.973  113.878 1.00 0.00   ? 37  VAL S N     1 
ATOM   6984 C CA    . VAL E 5 75  ? 144.908 96.929  113.364 1.00 0.00   ? 37  VAL S CA    1 
ATOM   6985 C C     . VAL E 5 75  ? 145.760 95.749  112.919 1.00 0.00   ? 37  VAL S C     1 
ATOM   6986 O O     . VAL E 5 75  ? 146.738 95.925  112.184 1.00 9.86   ? 37  VAL S O     1 
ATOM   6987 C CB    . VAL E 5 75  ? 144.038 97.439  112.198 1.00 10.05  ? 37  VAL S CB    1 
ATOM   6988 C CG1   . VAL E 5 75  ? 143.273 96.293  111.556 1.00 4.96   ? 37  VAL S CG1   1 
ATOM   6989 C CG2   . VAL E 5 75  ? 143.080 98.517  112.679 1.00 4.78   ? 37  VAL S CG2   1 
ATOM   6990 N N     . ARG E 5 76  ? 145.390 94.551  113.364 1.00 9.27   ? 38  ARG S N     1 
ATOM   6991 C CA    . ARG E 5 76  ? 146.072 93.327  112.971 1.00 8.96   ? 38  ARG S CA    1 
ATOM   6992 C C     . ARG E 5 76  ? 145.386 92.674  111.781 1.00 6.68   ? 38  ARG S C     1 
ATOM   6993 O O     . ARG E 5 76  ? 144.182 92.831  111.566 1.00 10.61  ? 38  ARG S O     1 
ATOM   6994 C CB    . ARG E 5 76  ? 146.115 92.330  114.130 1.00 7.53   ? 38  ARG S CB    1 
ATOM   6995 C CG    . ARG E 5 76  ? 147.410 92.320  114.907 1.00 12.04  ? 38  ARG S CG    1 
ATOM   6996 C CD    . ARG E 5 76  ? 147.258 91.554  116.210 1.00 14.39  ? 38  ARG S CD    1 
ATOM   6997 N NE    . ARG E 5 76  ? 146.796 90.189  115.996 1.00 20.43  ? 38  ARG S NE    1 
ATOM   6998 C CZ    . ARG E 5 76  ? 146.397 89.376  116.964 1.00 19.35  ? 38  ARG S CZ    1 
ATOM   6999 N NH1   . ARG E 5 76  ? 146.390 89.760  118.230 1.00 13.01  ? 38  ARG S NH1   1 
ATOM   7000 N NH2   . ARG E 5 76  ? 145.995 88.146  116.655 1.00 16.04  ? 38  ARG S NH2   1 
ATOM   7001 N N     . GLN E 5 77  ? 146.173 91.935  111.006 1.00 7.65   ? 39  GLN S N     1 
ATOM   7002 C CA    . GLN E 5 77  ? 145.644 91.027  109.994 1.00 8.39   ? 39  GLN S CA    1 
ATOM   7003 C C     . GLN E 5 77  ? 146.478 89.756  110.040 1.00 17.94  ? 39  GLN S C     1 
ATOM   7004 O O     . GLN E 5 77  ? 147.671 89.787  109.726 1.00 24.91  ? 39  GLN S O     1 
ATOM   7005 C CB    . GLN E 5 77  ? 145.675 91.645  108.598 1.00 6.59   ? 39  GLN S CB    1 
ATOM   7006 C CG    . GLN E 5 77  ? 145.071 90.743  107.534 1.00 13.29  ? 39  GLN S CG    1 
ATOM   7007 C CD    . GLN E 5 77  ? 145.077 91.371  106.158 1.00 20.58  ? 39  GLN S CD    1 
ATOM   7008 O OE1   . GLN E 5 77  ? 145.822 92.314  105.896 1.00 23.76  ? 39  GLN S OE1   1 
ATOM   7009 N NE2   . GLN E 5 77  ? 144.244 90.847  105.268 1.00 14.44  ? 39  GLN S NE2   1 
ATOM   7010 N N     . ALA E 5 78  ? 145.860 88.650  110.439 1.00 27.23  ? 40  ALA S N     1 
ATOM   7011 C CA    . ALA E 5 78  ? 146.549 87.376  110.441 1.00 19.18  ? 40  ALA S CA    1 
ATOM   7012 C C     . ALA E 5 78  ? 146.857 86.960  109.004 1.00 35.53  ? 40  ALA S C     1 
ATOM   7013 O O     . ALA E 5 78  ? 146.236 87.458  108.062 1.00 41.87  ? 40  ALA S O     1 
ATOM   7014 C CB    . ALA E 5 78  ? 145.702 86.320  111.145 1.00 25.23  ? 40  ALA S CB    1 
ATOM   7015 N N     . PRO E 5 79  ? 147.830 86.063  108.809 1.00 42.83  ? 41  PRO S N     1 
ATOM   7016 C CA    . PRO E 5 79  ? 148.235 85.711  107.436 1.00 38.27  ? 41  PRO S CA    1 
ATOM   7017 C C     . PRO E 5 79  ? 147.089 85.281  106.534 1.00 36.81  ? 41  PRO S C     1 
ATOM   7018 O O     . PRO E 5 79  ? 147.131 85.559  105.329 1.00 32.36  ? 41  PRO S O     1 
ATOM   7019 C CB    . PRO E 5 79  ? 149.232 84.569  107.661 1.00 35.50  ? 41  PRO S CB    1 
ATOM   7020 C CG    . PRO E 5 79  ? 149.849 84.884  108.976 1.00 32.34  ? 41  PRO S CG    1 
ATOM   7021 C CD    . PRO E 5 79  ? 148.761 85.511  109.811 1.00 35.08  ? 41  PRO S CD    1 
ATOM   7022 N N     . GLU E 5 80  ? 146.063 84.616  107.073 1.00 42.47  ? 42  GLU S N     1 
ATOM   7023 C CA    . GLU E 5 80  ? 144.919 84.230  106.256 1.00 38.42  ? 42  GLU S CA    1 
ATOM   7024 C C     . GLU E 5 80  ? 143.579 84.427  106.959 1.00 38.06  ? 42  GLU S C     1 
ATOM   7025 O O     . GLU E 5 80  ? 142.555 83.972  106.434 1.00 41.12  ? 42  GLU S O     1 
ATOM   7026 C CB    . GLU E 5 80  ? 145.044 82.767  105.806 1.00 37.36  ? 42  GLU S CB    1 
ATOM   7027 C CG    . GLU E 5 80  ? 146.146 82.511  104.787 1.00 39.03  ? 42  GLU S CG    1 
ATOM   7028 C CD    . GLU E 5 80  ? 147.461 82.126  105.434 1.00 40.12  ? 42  GLU S CD    1 
ATOM   7029 O OE1   . GLU E 5 80  ? 147.487 81.945  106.669 1.00 38.59  ? 42  GLU S OE1   1 
ATOM   7030 O OE2   . GLU E 5 80  ? 148.470 82.006  104.707 1.00 37.53  ? 42  GLU S OE2   1 
ATOM   7031 N N     . LYS E 5 81  ? 143.542 85.083  108.119 1.00 35.53  ? 43  LYS S N     1 
ATOM   7032 C CA    . LYS E 5 81  ? 142.316 85.194  108.900 1.00 36.95  ? 43  LYS S CA    1 
ATOM   7033 C C     . LYS E 5 81  ? 141.659 86.567  108.817 1.00 34.60  ? 43  LYS S C     1 
ATOM   7034 O O     . LYS E 5 81  ? 140.650 86.792  109.492 1.00 33.75  ? 43  LYS S O     1 
ATOM   7035 C CB    . LYS E 5 81  ? 142.591 84.842  110.366 1.00 34.16  ? 43  LYS S CB    1 
ATOM   7036 C CG    . LYS E 5 81  ? 143.376 83.553  110.561 1.00 31.99  ? 43  LYS S CG    1 
ATOM   7037 C CD    . LYS E 5 81  ? 142.746 82.393  109.806 1.00 33.27  ? 43  LYS S CD    1 
ATOM   7038 C CE    . LYS E 5 81  ? 143.367 81.068  110.215 1.00 34.91  ? 43  LYS S CE    1 
ATOM   7039 N NZ    . LYS E 5 81  ? 144.836 81.046  109.967 1.00 35.35  ? 43  LYS S NZ    1 
ATOM   7040 N N     . GLY E 5 82  ? 142.196 87.486  108.018 1.00 26.95  ? 44  GLY S N     1 
ATOM   7041 C CA    . GLY E 5 82  ? 141.562 88.775  107.829 1.00 23.83  ? 44  GLY S CA    1 
ATOM   7042 C C     . GLY E 5 82  ? 141.924 89.793  108.895 1.00 21.11  ? 44  GLY S C     1 
ATOM   7043 O O     . GLY E 5 82  ? 142.678 89.535  109.834 1.00 25.50  ? 44  GLY S O     1 
ATOM   7044 N N     . LEU E 5 83  ? 141.353 90.985  108.736 1.00 17.78  ? 45  LEU S N     1 
ATOM   7045 C CA    . LEU E 5 83  ? 141.675 92.109  109.604 1.00 8.55   ? 45  LEU S CA    1 
ATOM   7046 C C     . LEU E 5 83  ? 141.123 91.903  111.010 1.00 4.18   ? 45  LEU S C     1 
ATOM   7047 O O     . LEU E 5 83  ? 140.135 91.196  111.221 1.00 16.50  ? 45  LEU S O     1 
ATOM   7048 C CB    . LEU E 5 83  ? 141.120 93.411  109.028 1.00 1.19   ? 45  LEU S CB    1 
ATOM   7049 C CG    . LEU E 5 83  ? 141.501 93.791  107.599 1.00 5.96   ? 45  LEU S CG    1 
ATOM   7050 C CD1   . LEU E 5 83  ? 140.815 95.087  107.208 1.00 9.96   ? 45  LEU S CD1   1 
ATOM   7051 C CD2   . LEU E 5 83  ? 143.007 93.921  107.462 1.00 11.98  ? 45  LEU S CD2   1 
ATOM   7052 N N     . GLU E 5 84  ? 141.779 92.540  111.979 1.00 8.84   ? 46  GLU S N     1 
ATOM   7053 C CA    . GLU E 5 84  ? 141.338 92.507  113.369 1.00 4.00   ? 46  GLU S CA    1 
ATOM   7054 C C     . GLU E 5 84  ? 141.842 93.762  114.064 1.00 1.63   ? 46  GLU S C     1 
ATOM   7055 O O     . GLU E 5 84  ? 143.045 94.038  114.048 1.00 8.87   ? 46  GLU S O     1 
ATOM   7056 C CB    . GLU E 5 84  ? 141.849 91.255  114.084 1.00 7.70   ? 46  GLU S CB    1 
ATOM   7057 C CG    . GLU E 5 84  ? 141.724 91.315  115.596 1.00 4.11   ? 46  GLU S CG    1 
ATOM   7058 C CD    . GLU E 5 84  ? 142.100 90.008  116.264 1.00 14.71  ? 46  GLU S CD    1 
ATOM   7059 O OE1   . GLU E 5 84  ? 142.422 89.041  115.543 1.00 25.06  ? 46  GLU S OE1   1 
ATOM   7060 O OE2   . GLU E 5 84  ? 142.074 89.948  117.511 1.00 17.89  ? 46  GLU S OE2   1 
ATOM   7061 N N     . TRP E 5 85  ? 140.927 94.516  114.664 1.00 4.90   ? 47  TRP S N     1 
ATOM   7062 C CA    . TRP E 5 85  ? 141.300 95.719  115.392 1.00 6.04   ? 47  TRP S CA    1 
ATOM   7063 C C     . TRP E 5 85  ? 142.070 95.364  116.660 1.00 3.91   ? 47  TRP S C     1 
ATOM   7064 O O     . TRP E 5 85  ? 141.796 94.358  117.319 1.00 10.61  ? 47  TRP S O     1 
ATOM   7065 C CB    . TRP E 5 85  ? 140.056 96.532  115.741 1.00 2.07   ? 47  TRP S CB    1 
ATOM   7066 C CG    . TRP E 5 85  ? 140.351 97.814  116.441 1.00 0.00   ? 47  TRP S CG    1 
ATOM   7067 C CD1   . TRP E 5 85  ? 140.851 98.955  115.887 1.00 2.66   ? 47  TRP S CD1   1 
ATOM   7068 C CD2   . TRP E 5 85  ? 140.165 98.091  117.832 1.00 3.00   ? 47  TRP S CD2   1 
ATOM   7069 N NE1   . TRP E 5 85  ? 140.987 99.926  116.848 1.00 0.00   ? 47  TRP S NE1   1 
ATOM   7070 C CE2   . TRP E 5 85  ? 140.573 99.419  118.051 1.00 1.89   ? 47  TRP S CE2   1 
ATOM   7071 C CE3   . TRP E 5 85  ? 139.692 97.343  118.914 1.00 0.00   ? 47  TRP S CE3   1 
ATOM   7072 C CZ2   . TRP E 5 85  ? 140.522 100.016 119.307 1.00 0.00   ? 47  TRP S CZ2   1 
ATOM   7073 C CZ3   . TRP E 5 85  ? 139.643 97.937  120.158 1.00 0.00   ? 47  TRP S CZ3   1 
ATOM   7074 C CH2   . TRP E 5 85  ? 140.056 99.259  120.345 1.00 0.00   ? 47  TRP S CH2   1 
ATOM   7075 N N     . VAL E 5 86  ? 143.044 96.207  117.001 1.00 0.87   ? 48  VAL S N     1 
ATOM   7076 C CA    . VAL E 5 86  ? 143.902 95.951  118.153 1.00 3.15   ? 48  VAL S CA    1 
ATOM   7077 C C     . VAL E 5 86  ? 143.755 97.059  119.184 1.00 0.00   ? 48  VAL S C     1 
ATOM   7078 O O     . VAL E 5 86  ? 143.344 96.808  120.322 1.00 0.00   ? 48  VAL S O     1 
ATOM   7079 C CB    . VAL E 5 86  ? 145.375 95.803  117.730 1.00 1.12   ? 48  VAL S CB    1 
ATOM   7080 C CG1   . VAL E 5 86  ? 146.262 95.608  118.949 1.00 3.25   ? 48  VAL S CG1   1 
ATOM   7081 C CG2   . VAL E 5 86  ? 145.527 94.657  116.766 1.00 0.00   ? 48  VAL S CG2   1 
ATOM   7082 N N     . ALA E 5 87  ? 144.088 98.288  118.803 1.00 0.00   ? 49  ALA S N     1 
ATOM   7083 C CA    . ALA E 5 87  ? 144.146 99.360  119.790 1.00 0.00   ? 49  ALA S CA    1 
ATOM   7084 C C     . ALA E 5 87  ? 143.871 100.695 119.117 1.00 0.00   ? 49  ALA S C     1 
ATOM   7085 O O     . ALA E 5 87  ? 143.856 100.803 117.891 1.00 14.48  ? 49  ALA S O     1 
ATOM   7086 C CB    . ALA E 5 87  ? 145.499 99.383  120.506 1.00 0.00   ? 49  ALA S CB    1 
ATOM   7087 N N     . TYR E 5 88  ? 143.662 101.718 119.943 1.00 3.61   ? 50  TYR S N     1 
ATOM   7088 C CA    . TYR E 5 88  ? 143.416 103.065 119.448 1.00 0.00   ? 50  TYR S CA    1 
ATOM   7089 C C     . TYR E 5 88  ? 143.822 104.082 120.503 1.00 8.99   ? 50  TYR S C     1 
ATOM   7090 O O     . TYR E 5 88  ? 143.631 103.860 121.701 1.00 17.03  ? 50  TYR S O     1 
ATOM   7091 C CB    . TYR E 5 88  ? 141.944 103.258 119.069 1.00 0.00   ? 50  TYR S CB    1 
ATOM   7092 C CG    . TYR E 5 88  ? 141.465 104.697 119.048 1.00 1.39   ? 50  TYR S CG    1 
ATOM   7093 C CD1   . TYR E 5 88  ? 141.764 105.533 117.983 1.00 0.00   ? 50  TYR S CD1   1 
ATOM   7094 C CD2   . TYR E 5 88  ? 140.701 105.213 120.087 1.00 0.00   ? 50  TYR S CD2   1 
ATOM   7095 C CE1   . TYR E 5 88  ? 141.320 106.840 117.954 1.00 0.00   ? 50  TYR S CE1   1 
ATOM   7096 C CE2   . TYR E 5 88  ? 140.254 106.517 120.067 1.00 0.00   ? 50  TYR S CE2   1 
ATOM   7097 C CZ    . TYR E 5 88  ? 140.566 107.326 118.999 1.00 0.00   ? 50  TYR S CZ    1 
ATOM   7098 O OH    . TYR E 5 88  ? 140.122 108.628 118.976 1.00 0.03   ? 50  TYR S OH    1 
ATOM   7099 N N     . ILE E 5 89  ? 144.389 105.194 120.043 1.00 6.38   ? 51  ILE S N     1 
ATOM   7100 C CA    . ILE E 5 89  ? 144.716 106.333 120.890 1.00 0.00   ? 51  ILE S CA    1 
ATOM   7101 C C     . ILE E 5 89  ? 144.106 107.578 120.259 1.00 0.00   ? 51  ILE S C     1 
ATOM   7102 O O     . ILE E 5 89  ? 144.224 107.792 119.046 1.00 3.40   ? 51  ILE S O     1 
ATOM   7103 C CB    . ILE E 5 89  ? 146.237 106.485 121.090 1.00 2.06   ? 51  ILE S CB    1 
ATOM   7104 C CG1   . ILE E 5 89  ? 146.541 107.658 122.022 1.00 10.81  ? 51  ILE S CG1   1 
ATOM   7105 C CG2   . ILE E 5 89  ? 146.960 106.642 119.760 1.00 3.66   ? 51  ILE S CG2   1 
ATOM   7106 C CD1   . ILE E 5 89  ? 147.862 107.534 122.738 1.00 0.71   ? 51  ILE S CD1   1 
ATOM   7107 N N     . SER E 5 90  ? 143.434 108.381 121.077 1.00 0.00   ? 52  SER S N     1 
ATOM   7108 C CA    . SER E 5 90  ? 142.756 109.567 120.583 1.00 0.00   ? 52  SER S CA    1 
ATOM   7109 C C     . SER E 5 90  ? 143.758 110.678 120.286 1.00 5.69   ? 52  SER S C     1 
ATOM   7110 O O     . SER E 5 90  ? 144.938 110.606 120.639 1.00 4.52   ? 52  SER S O     1 
ATOM   7111 C CB    . SER E 5 90  ? 141.718 110.049 121.594 1.00 0.00   ? 52  SER S CB    1 
ATOM   7112 N N     . SER E 5 91  ? 143.271 111.715 119.608 1.00 13.15  ? 53  SER S N     1 
ATOM   7113 C CA    . SER E 5 91  ? 144.063 112.922 119.426 1.00 4.30   ? 53  SER S CA    1 
ATOM   7114 C C     . SER E 5 91  ? 144.370 113.538 120.784 1.00 8.32   ? 53  SER S C     1 
ATOM   7115 O O     . SER E 5 91  ? 143.481 113.691 121.626 1.00 5.00   ? 53  SER S O     1 
ATOM   7116 C CB    . SER E 5 91  ? 143.314 113.917 118.541 1.00 0.00   ? 53  SER S CB    1 
ATOM   7117 O OG    . SER E 5 91  ? 144.038 115.126 118.403 1.00 7.93   ? 53  SER S OG    1 
ATOM   7118 N N     . GLY E 5 92  ? 145.638 113.873 121.006 1.00 5.28   ? 54  GLY S N     1 
ATOM   7119 C CA    . GLY E 5 92  ? 146.041 114.365 122.306 1.00 12.75  ? 54  GLY S CA    1 
ATOM   7120 C C     . GLY E 5 92  ? 146.097 113.316 123.391 1.00 9.64   ? 54  GLY S C     1 
ATOM   7121 O O     . GLY E 5 92  ? 146.235 113.671 124.566 1.00 13.05  ? 54  GLY S O     1 
ATOM   7122 N N     . SER E 5 93  ? 145.981 112.035 123.032 1.00 6.55   ? 55  SER S N     1 
ATOM   7123 C CA    . SER E 5 93  ? 146.033 110.921 123.980 1.00 0.00   ? 55  SER S CA    1 
ATOM   7124 C C     . SER E 5 93  ? 144.944 111.026 125.044 1.00 0.83   ? 55  SER S C     1 
ATOM   7125 O O     . SER E 5 93  ? 145.122 110.564 126.174 1.00 10.27  ? 55  SER S O     1 
ATOM   7126 C CB    . SER E 5 93  ? 147.413 110.814 124.637 1.00 7.07   ? 55  SER S CB    1 
ATOM   7127 O OG    . SER E 5 93  ? 148.433 110.682 123.663 1.00 13.59  ? 55  SER S OG    1 
ATOM   7128 N N     . GLY E 5 94  ? 143.811 111.637 124.694 1.00 17.08  ? 56  GLY S N     1 
ATOM   7129 C CA    . GLY E 5 94  ? 142.738 111.793 125.663 1.00 9.30   ? 56  GLY S CA    1 
ATOM   7130 C C     . GLY E 5 94  ? 142.144 110.468 126.101 1.00 6.73   ? 56  GLY S C     1 
ATOM   7131 O O     . GLY E 5 94  ? 141.949 110.223 127.293 1.00 8.15   ? 56  GLY S O     1 
ATOM   7132 N N     . THR E 5 95  ? 141.850 109.594 125.141 1.00 9.09   ? 57  THR S N     1 
ATOM   7133 C CA    . THR E 5 95  ? 141.296 108.278 125.421 1.00 4.95   ? 57  THR S CA    1 
ATOM   7134 C C     . THR E 5 95  ? 142.139 107.215 124.735 1.00 6.98   ? 57  THR S C     1 
ATOM   7135 O O     . THR E 5 95  ? 142.554 107.384 123.586 1.00 18.24  ? 57  THR S O     1 
ATOM   7136 C CB    . THR E 5 95  ? 139.837 108.160 124.958 1.00 1.48   ? 57  THR S CB    1 
ATOM   7137 O OG1   . THR E 5 95  ? 139.755 108.415 123.552 1.00 10.94  ? 57  THR S OG1   1 
ATOM   7138 C CG2   . THR E 5 95  ? 138.957 109.150 125.705 1.00 3.69   ? 57  THR S CG2   1 
ATOM   7139 N N     . ILE E 5 96  ? 142.387 106.122 125.450 1.00 2.95   ? 58  ILE S N     1 
ATOM   7140 C CA    . ILE E 5 96  ? 143.190 105.012 124.958 1.00 0.49   ? 58  ILE S CA    1 
ATOM   7141 C C     . ILE E 5 96  ? 142.395 103.730 125.157 1.00 2.44   ? 58  ILE S C     1 
ATOM   7142 O O     . ILE E 5 96  ? 141.872 103.485 126.250 1.00 9.49   ? 58  ILE S O     1 
ATOM   7143 C CB    . ILE E 5 96  ? 144.548 104.931 125.680 1.00 1.14   ? 58  ILE S CB    1 
ATOM   7144 C CG1   . ILE E 5 96  ? 145.458 106.078 125.238 1.00 7.82   ? 58  ILE S CG1   1 
ATOM   7145 C CG2   . ILE E 5 96  ? 145.210 103.596 125.425 1.00 0.00   ? 58  ILE S CG2   1 
ATOM   7146 C CD1   . ILE E 5 96  ? 146.727 106.193 126.050 1.00 11.24  ? 58  ILE S CD1   1 
ATOM   7147 N N     . TYR E 5 97  ? 142.300 102.918 124.108 1.00 1.51   ? 59  TYR S N     1 
ATOM   7148 C CA    . TYR E 5 97  ? 141.533 101.684 124.152 1.00 1.47   ? 59  TYR S CA    1 
ATOM   7149 C C     . TYR E 5 97  ? 142.327 100.544 123.531 1.00 3.44   ? 59  TYR S C     1 
ATOM   7150 O O     . TYR E 5 97  ? 143.147 100.752 122.634 1.00 7.87   ? 59  TYR S O     1 
ATOM   7151 C CB    . TYR E 5 97  ? 140.212 101.814 123.408 1.00 0.00   ? 59  TYR S CB    1 
ATOM   7152 C CG    . TYR E 5 97  ? 139.212 102.774 124.010 1.00 4.01   ? 59  TYR S CG    1 
ATOM   7153 C CD1   . TYR E 5 97  ? 138.327 102.357 124.995 1.00 18.89  ? 59  TYR S CD1   1 
ATOM   7154 C CD2   . TYR E 5 97  ? 139.127 104.086 123.567 1.00 9.82   ? 59  TYR S CD2   1 
ATOM   7155 C CE1   . TYR E 5 97  ? 137.403 103.228 125.539 1.00 16.76  ? 59  TYR S CE1   1 
ATOM   7156 C CE2   . TYR E 5 97  ? 138.205 104.964 124.105 1.00 11.08  ? 59  TYR S CE2   1 
ATOM   7157 C CZ    . TYR E 5 97  ? 137.346 104.529 125.090 1.00 13.52  ? 59  TYR S CZ    1 
ATOM   7158 O OH    . TYR E 5 97  ? 136.427 105.400 125.628 1.00 23.11  ? 59  TYR S OH    1 
ATOM   7159 N N     . TYR E 5 98  ? 142.045 99.331  124.002 1.00 4.49   ? 60  TYR S N     1 
ATOM   7160 C CA    . TYR E 5 98  ? 142.664 98.121  123.483 1.00 3.54   ? 60  TYR S CA    1 
ATOM   7161 C C     . TYR E 5 98  ? 141.593 97.061  123.277 1.00 4.33   ? 60  TYR S C     1 
ATOM   7162 O O     . TYR E 5 98  ? 140.527 97.098  123.895 1.00 9.29   ? 60  TYR S O     1 
ATOM   7163 C CB    . TYR E 5 98  ? 143.745 97.576  124.425 1.00 0.00   ? 60  TYR S CB    1 
ATOM   7164 C CG    . TYR E 5 98  ? 144.774 98.592  124.848 1.00 0.00   ? 60  TYR S CG    1 
ATOM   7165 C CD1   . TYR E 5 98  ? 145.913 98.809  124.089 1.00 0.00   ? 60  TYR S CD1   1 
ATOM   7166 C CD2   . TYR E 5 98  ? 144.611 99.330  126.011 1.00 0.00   ? 60  TYR S CD2   1 
ATOM   7167 C CE1   . TYR E 5 98  ? 146.858 99.734  124.474 1.00 6.94   ? 60  TYR S CE1   1 
ATOM   7168 C CE2   . TYR E 5 98  ? 145.550 100.256 126.404 1.00 4.43   ? 60  TYR S CE2   1 
ATOM   7169 C CZ    . TYR E 5 98  ? 146.672 100.456 125.632 1.00 8.03   ? 60  TYR S CZ    1 
ATOM   7170 O OH    . TYR E 5 98  ? 147.613 101.381 126.021 1.00 13.21  ? 60  TYR S OH    1 
ATOM   7171 N N     . ALA E 5 99  ? 141.891 96.114  122.394 1.00 6.20   ? 61  ALA S N     1 
ATOM   7172 C CA    . ALA E 5 99  ? 141.028 94.955  122.231 1.00 1.04   ? 61  ALA S CA    1 
ATOM   7173 C C     . ALA E 5 99  ? 141.175 94.019  123.424 1.00 10.56  ? 61  ALA S C     1 
ATOM   7174 O O     . ALA E 5 99  ? 142.198 94.012  124.114 1.00 16.32  ? 61  ALA S O     1 
ATOM   7175 C CB    . ALA E 5 99  ? 141.361 94.214  120.937 1.00 4.81   ? 61  ALA S CB    1 
ATOM   7176 N N     . ASP E 5 100 ? 140.131 93.224  123.669 1.00 21.22  ? 62  ASP S N     1 
ATOM   7177 C CA    . ASP E 5 100 ? 140.161 92.293  124.793 1.00 13.70  ? 62  ASP S CA    1 
ATOM   7178 C C     . ASP E 5 100 ? 141.255 91.247  124.628 1.00 8.62   ? 62  ASP S C     1 
ATOM   7179 O O     . ASP E 5 100 ? 141.746 90.700  125.622 1.00 15.88  ? 62  ASP S O     1 
ATOM   7180 C CB    . ASP E 5 100 ? 138.799 91.616  124.951 1.00 14.59  ? 62  ASP S CB    1 
ATOM   7181 N N     . THR E 5 101 ? 141.650 90.956  123.387 1.00 12.97  ? 63  THR S N     1 
ATOM   7182 C CA    . THR E 5 101 ? 142.721 89.994  123.155 1.00 11.29  ? 63  THR S CA    1 
ATOM   7183 C C     . THR E 5 101 ? 144.067 90.525  123.629 1.00 13.12  ? 63  THR S C     1 
ATOM   7184 O O     . THR E 5 101 ? 144.894 89.755  124.132 1.00 20.70  ? 63  THR S O     1 
ATOM   7185 C CB    . THR E 5 101 ? 142.791 89.633  121.671 1.00 16.16  ? 63  THR S CB    1 
ATOM   7186 O OG1   . THR E 5 101 ? 141.481 89.297  121.198 1.00 20.37  ? 63  THR S OG1   1 
ATOM   7187 C CG2   . THR E 5 101 ? 143.719 88.449  121.452 1.00 16.24  ? 63  THR S CG2   1 
ATOM   7188 N N     . VAL E 5 102 ? 144.304 91.828  123.488 1.00 18.37  ? 64  VAL S N     1 
ATOM   7189 C CA    . VAL E 5 102 ? 145.591 92.433  123.810 1.00 16.59  ? 64  VAL S CA    1 
ATOM   7190 C C     . VAL E 5 102 ? 145.530 93.317  125.041 1.00 11.90  ? 64  VAL S C     1 
ATOM   7191 O O     . VAL E 5 102 ? 146.558 93.894  125.424 1.00 14.33  ? 64  VAL S O     1 
ATOM   7192 C CB    . VAL E 5 102 ? 146.147 93.227  122.613 1.00 17.75  ? 64  VAL S CB    1 
ATOM   7193 C CG1   . VAL E 5 102 ? 146.210 92.345  121.377 1.00 17.21  ? 64  VAL S CG1   1 
ATOM   7194 C CG2   . VAL E 5 102 ? 145.299 94.461  122.356 1.00 13.06  ? 64  VAL S CG2   1 
ATOM   7195 N N     . LYS E 5 103 ? 144.364 93.455  125.670 1.00 14.18  ? 65  LYS S N     1 
ATOM   7196 C CA    . LYS E 5 103 ? 144.257 94.271  126.872 1.00 11.45  ? 65  LYS S CA    1 
ATOM   7197 C C     . LYS E 5 103 ? 145.107 93.681  127.989 1.00 23.94  ? 65  LYS S C     1 
ATOM   7198 O O     . LYS E 5 103 ? 145.065 92.475  128.250 1.00 24.46  ? 65  LYS S O     1 
ATOM   7199 C CB    . LYS E 5 103 ? 142.797 94.375  127.313 1.00 8.74   ? 65  LYS S CB    1 
ATOM   7200 N N     . GLY E 5 104 ? 145.880 94.538  128.651 1.00 19.43  ? 66  GLY S N     1 
ATOM   7201 C CA    . GLY E 5 104 ? 146.788 94.106  129.690 1.00 11.87  ? 66  GLY S CA    1 
ATOM   7202 C C     . GLY E 5 104 ? 148.144 93.645  129.206 1.00 16.73  ? 66  GLY S C     1 
ATOM   7203 O O     . GLY E 5 104 ? 149.012 93.353  130.037 1.00 21.51  ? 66  GLY S O     1 
ATOM   7204 N N     . ARG E 5 105 ? 148.356 93.571  127.896 1.00 20.02  ? 67  ARG S N     1 
ATOM   7205 C CA    . ARG E 5 105 ? 149.635 93.180  127.317 1.00 13.85  ? 67  ARG S CA    1 
ATOM   7206 C C     . ARG E 5 105 ? 150.198 94.220  126.366 1.00 13.31  ? 67  ARG S C     1 
ATOM   7207 O O     . ARG E 5 105 ? 151.415 94.416  126.325 1.00 15.88  ? 67  ARG S O     1 
ATOM   7208 C CB    . ARG E 5 105 ? 149.497 91.843  126.574 1.00 16.25  ? 67  ARG S CB    1 
ATOM   7209 C CG    . ARG E 5 105 ? 149.003 90.695  127.433 1.00 22.55  ? 67  ARG S CG    1 
ATOM   7210 C CD    . ARG E 5 105 ? 149.061 89.380  126.672 1.00 22.46  ? 67  ARG S CD    1 
ATOM   7211 N NE    . ARG E 5 105 ? 148.300 89.434  125.429 1.00 21.70  ? 67  ARG S NE    1 
ATOM   7212 C CZ    . ARG E 5 105 ? 148.833 89.336  124.219 1.00 22.97  ? 67  ARG S CZ    1 
ATOM   7213 N NH1   . ARG E 5 105 ? 150.135 89.177  124.049 1.00 20.82  ? 67  ARG S NH1   1 
ATOM   7214 N NH2   . ARG E 5 105 ? 148.040 89.400  123.154 1.00 17.55  ? 67  ARG S NH2   1 
ATOM   7215 N N     . PHE E 5 106 ? 149.345 94.890  125.599 1.00 13.68  ? 68  PHE S N     1 
ATOM   7216 C CA    . PHE E 5 106 ? 149.771 95.892  124.634 1.00 14.91  ? 68  PHE S CA    1 
ATOM   7217 C C     . PHE E 5 106 ? 149.565 97.287  125.210 1.00 13.71  ? 68  PHE S C     1 
ATOM   7218 O O     . PHE E 5 106 ? 148.665 97.517  126.022 1.00 15.26  ? 68  PHE S O     1 
ATOM   7219 C CB    . PHE E 5 106 ? 148.999 95.760  123.317 1.00 12.13  ? 68  PHE S CB    1 
ATOM   7220 C CG    . PHE E 5 106 ? 149.400 94.571  122.478 1.00 12.97  ? 68  PHE S CG    1 
ATOM   7221 C CD1   . PHE E 5 106 ? 150.034 93.475  123.041 1.00 21.74  ? 68  PHE S CD1   1 
ATOM   7222 C CD2   . PHE E 5 106 ? 149.133 94.552  121.120 1.00 13.07  ? 68  PHE S CD2   1 
ATOM   7223 C CE1   . PHE E 5 106 ? 150.392 92.388  122.268 1.00 18.94  ? 68  PHE S CE1   1 
ATOM   7224 C CE2   . PHE E 5 106 ? 149.490 93.469  120.342 1.00 13.55  ? 68  PHE S CE2   1 
ATOM   7225 C CZ    . PHE E 5 106 ? 150.121 92.387  120.917 1.00 15.03  ? 68  PHE S CZ    1 
ATOM   7226 N N     . THR E 5 107 ? 150.415 98.217  124.782 1.00 9.04   ? 69  THR S N     1 
ATOM   7227 C CA    . THR E 5 107 ? 150.336 99.608  125.211 1.00 1.15   ? 69  THR S CA    1 
ATOM   7228 C C     . THR E 5 107 ? 150.543 100.495 123.995 1.00 5.32   ? 69  THR S C     1 
ATOM   7229 O O     . THR E 5 107 ? 151.597 100.435 123.355 1.00 10.81  ? 69  THR S O     1 
ATOM   7230 C CB    . THR E 5 107 ? 151.381 99.921  126.287 1.00 17.51  ? 69  THR S CB    1 
ATOM   7231 O OG1   . THR E 5 107 ? 151.176 99.067  127.419 1.00 19.00  ? 69  THR S OG1   1 
ATOM   7232 C CG2   . THR E 5 107 ? 151.271 101.371 126.730 1.00 9.10   ? 69  THR S CG2   1 
ATOM   7233 N N     . ILE E 5 108 ? 149.541 101.309 123.675 1.00 6.14   ? 70  ILE S N     1 
ATOM   7234 C CA    . ILE E 5 108 ? 149.602 102.233 122.550 1.00 0.00   ? 70  ILE S CA    1 
ATOM   7235 C C     . ILE E 5 108 ? 149.898 103.628 123.080 1.00 1.50   ? 70  ILE S C     1 
ATOM   7236 O O     . ILE E 5 108 ? 149.397 104.027 124.140 1.00 8.17   ? 70  ILE S O     1 
ATOM   7237 C CB    . ILE E 5 108 ? 148.296 102.208 121.728 1.00 8.78   ? 70  ILE S CB    1 
ATOM   7238 C CG1   . ILE E 5 108 ? 148.435 103.050 120.459 1.00 4.90   ? 70  ILE S CG1   1 
ATOM   7239 C CG2   . ILE E 5 108 ? 147.118 102.688 122.554 1.00 2.32   ? 70  ILE S CG2   1 
ATOM   7240 C CD1   . ILE E 5 108 ? 147.211 103.017 119.571 1.00 0.00   ? 70  ILE S CD1   1 
ATOM   7241 N N     . SER E 5 109 ? 150.737 104.363 122.357 1.00 3.49   ? 71  SER S N     1 
ATOM   7242 C CA    . SER E 5 109 ? 151.091 105.723 122.733 1.00 7.86   ? 71  SER S CA    1 
ATOM   7243 C C     . SER E 5 109 ? 151.424 106.501 121.470 1.00 6.84   ? 71  SER S C     1 
ATOM   7244 O O     . SER E 5 109 ? 151.516 105.941 120.377 1.00 5.01   ? 71  SER S O     1 
ATOM   7245 C CB    . SER E 5 109 ? 152.262 105.749 123.722 1.00 9.15   ? 71  SER S CB    1 
ATOM   7246 O OG    . SER E 5 109 ? 153.403 105.101 123.187 1.00 13.27  ? 71  SER S OG    1 
ATOM   7247 N N     . ARG E 5 110 ? 151.603 107.808 121.628 1.00 12.91  ? 72  ARG S N     1 
ATOM   7248 C CA    . ARG E 5 110 ? 151.933 108.650 120.490 1.00 13.02  ? 72  ARG S CA    1 
ATOM   7249 C C     . ARG E 5 110 ? 152.835 109.786 120.943 1.00 13.69  ? 72  ARG S C     1 
ATOM   7250 O O     . ARG E 5 110 ? 152.672 110.322 122.042 1.00 16.33  ? 72  ARG S O     1 
ATOM   7251 C CB    . ARG E 5 110 ? 150.667 109.200 119.822 1.00 5.38   ? 72  ARG S CB    1 
ATOM   7252 C CG    . ARG E 5 110 ? 149.791 110.038 120.734 1.00 7.97   ? 72  ARG S CG    1 
ATOM   7253 C CD    . ARG E 5 110 ? 148.423 110.247 120.119 1.00 11.51  ? 72  ARG S CD    1 
ATOM   7254 N NE    . ARG E 5 110 ? 148.494 111.049 118.905 1.00 22.85  ? 72  ARG S NE    1 
ATOM   7255 C CZ    . ARG E 5 110 ? 147.641 110.950 117.895 1.00 7.33   ? 72  ARG S CZ    1 
ATOM   7256 N NH1   . ARG E 5 110 ? 146.635 110.093 117.923 1.00 8.45   ? 72  ARG S NH1   1 
ATOM   7257 N NH2   . ARG E 5 110 ? 147.804 111.728 116.830 1.00 0.00   ? 72  ARG S NH2   1 
ATOM   7258 N N     . ASP E 5 111 ? 153.793 110.135 120.090 1.00 14.90  ? 73  ASP S N     1 
ATOM   7259 C CA    . ASP E 5 111 ? 154.659 111.293 120.285 1.00 12.56  ? 73  ASP S CA    1 
ATOM   7260 C C     . ASP E 5 111 ? 154.360 112.259 119.144 1.00 17.22  ? 73  ASP S C     1 
ATOM   7261 O O     . ASP E 5 111 ? 154.858 112.090 118.025 1.00 21.24  ? 73  ASP S O     1 
ATOM   7262 C CB    . ASP E 5 111 ? 156.129 110.888 120.324 1.00 14.44  ? 73  ASP S CB    1 
ATOM   7263 C CG    . ASP E 5 111 ? 156.958 111.791 121.218 1.00 26.14  ? 73  ASP S CG    1 
ATOM   7264 O OD1   . ASP E 5 111 ? 156.446 112.852 121.632 1.00 26.43  ? 73  ASP S OD1   1 
ATOM   7265 O OD2   . ASP E 5 111 ? 158.119 111.438 121.509 1.00 22.86  ? 73  ASP S OD2   1 
ATOM   7266 N N     . ASP E 5 112 ? 153.512 113.245 119.430 1.00 14.28  ? 74  ASP S N     1 
ATOM   7267 C CA    . ASP E 5 112 ? 153.137 114.229 118.418 1.00 19.67  ? 74  ASP S CA    1 
ATOM   7268 C C     . ASP E 5 112 ? 154.303 115.077 117.918 1.00 22.00  ? 74  ASP S C     1 
ATOM   7269 O O     . ASP E 5 112 ? 154.375 115.303 116.698 1.00 17.52  ? 74  ASP S O     1 
ATOM   7270 C CB    . ASP E 5 112 ? 152.009 115.117 118.959 1.00 18.72  ? 74  ASP S CB    1 
ATOM   7271 C CG    . ASP E 5 112 ? 150.742 114.336 119.245 1.00 21.73  ? 74  ASP S CG    1 
ATOM   7272 O OD1   . ASP E 5 112 ? 150.389 113.459 118.430 1.00 13.51  ? 74  ASP S OD1   1 
ATOM   7273 O OD2   . ASP E 5 112 ? 150.101 114.599 120.283 1.00 30.56  ? 74  ASP S OD2   1 
ATOM   7274 N N     . PRO E 5 113 ? 155.211 115.594 118.762 1.00 23.95  ? 75  PRO S N     1 
ATOM   7275 C CA    . PRO E 5 113 ? 156.304 116.420 118.215 1.00 18.15  ? 75  PRO S CA    1 
ATOM   7276 C C     . PRO E 5 113 ? 157.134 115.715 117.156 1.00 22.56  ? 75  PRO S C     1 
ATOM   7277 O O     . PRO E 5 113 ? 157.563 116.354 116.187 1.00 21.19  ? 75  PRO S O     1 
ATOM   7278 C CB    . PRO E 5 113 ? 157.135 116.760 119.458 1.00 20.46  ? 75  PRO S CB    1 
ATOM   7279 C CG    . PRO E 5 113 ? 156.156 116.732 120.567 1.00 21.93  ? 75  PRO S CG    1 
ATOM   7280 C CD    . PRO E 5 113 ? 155.211 115.615 120.237 1.00 22.07  ? 75  PRO S CD    1 
ATOM   7281 N N     . LYS E 5 114 ? 157.376 114.415 117.309 1.00 16.70  ? 76  LYS S N     1 
ATOM   7282 C CA    . LYS E 5 114 ? 158.065 113.638 116.289 1.00 17.71  ? 76  LYS S CA    1 
ATOM   7283 C C     . LYS E 5 114 ? 157.107 112.883 115.378 1.00 20.46  ? 76  LYS S C     1 
ATOM   7284 O O     . LYS E 5 114 ? 157.565 112.152 114.493 1.00 21.83  ? 76  LYS S O     1 
ATOM   7285 C CB    . LYS E 5 114 ? 159.050 112.662 116.940 1.00 17.01  ? 76  LYS S CB    1 
ATOM   7286 C CG    . LYS E 5 114 ? 158.397 111.549 117.731 1.00 17.10  ? 76  LYS S CG    1 
ATOM   7287 C CD    . LYS E 5 114 ? 159.410 110.817 118.600 1.00 22.39  ? 76  LYS S CD    1 
ATOM   7288 C CE    . LYS E 5 114 ? 160.605 110.345 117.788 1.00 24.77  ? 76  LYS S CE    1 
ATOM   7289 N NZ    . LYS E 5 114 ? 160.279 109.147 116.966 1.00 21.07  ? 76  LYS S NZ    1 
ATOM   7290 N N     . ASN E 5 115 ? 155.795 113.049 115.571 1.00 16.04  ? 77  ASN S N     1 
ATOM   7291 C CA    . ASN E 5 115 ? 154.772 112.467 114.698 1.00 7.79   ? 77  ASN S CA    1 
ATOM   7292 C C     . ASN E 5 115 ? 154.932 110.953 114.574 1.00 7.38   ? 77  ASN S C     1 
ATOM   7293 O O     . ASN E 5 115 ? 154.989 110.400 113.475 1.00 18.21  ? 77  ASN S O     1 
ATOM   7294 C CB    . ASN E 5 115 ? 154.786 113.126 113.317 1.00 4.01   ? 77  ASN S CB    1 
ATOM   7295 C CG    . ASN E 5 115 ? 154.593 114.623 113.383 1.00 16.22  ? 77  ASN S CG    1 
ATOM   7296 O OD1   . ASN E 5 115 ? 153.671 115.114 114.033 1.00 27.35  ? 77  ASN S OD1   1 
ATOM   7297 N ND2   . ASN E 5 115 ? 155.464 115.361 112.707 1.00 13.90  ? 77  ASN S ND2   1 
ATOM   7298 N N     . THR E 5 116 ? 155.006 110.275 115.717 1.00 1.28   ? 78  THR S N     1 
ATOM   7299 C CA    . THR E 5 116 ? 155.199 108.832 115.719 1.00 4.71   ? 78  THR S CA    1 
ATOM   7300 C C     . THR E 5 116 ? 154.138 108.155 116.575 1.00 6.74   ? 78  THR S C     1 
ATOM   7301 O O     . THR E 5 116 ? 153.695 108.704 117.587 1.00 9.42   ? 78  THR S O     1 
ATOM   7302 C CB    . THR E 5 116 ? 156.601 108.457 116.217 1.00 18.39  ? 78  THR S CB    1 
ATOM   7303 O OG1   . THR E 5 116 ? 157.568 109.306 115.588 1.00 26.71  ? 78  THR S OG1   1 
ATOM   7304 C CG2   . THR E 5 116 ? 156.925 107.018 115.859 1.00 9.08   ? 78  THR S CG2   1 
ATOM   7305 N N     . LEU E 5 117 ? 153.722 106.966 116.147 1.00 7.44   ? 79  LEU S N     1 
ATOM   7306 C CA    . LEU E 5 117 ? 152.775 106.132 116.877 1.00 5.92   ? 79  LEU S CA    1 
ATOM   7307 C C     . LEU E 5 117 ? 153.487 104.878 117.359 1.00 15.27  ? 79  LEU S C     1 
ATOM   7308 O O     . LEU E 5 117 ? 154.140 104.192 116.568 1.00 17.35  ? 79  LEU S O     1 
ATOM   7309 C CB    . LEU E 5 117 ? 151.583 105.759 115.997 1.00 5.76   ? 79  LEU S CB    1 
ATOM   7310 C CG    . LEU E 5 117 ? 150.534 104.836 116.614 1.00 2.07   ? 79  LEU S CG    1 
ATOM   7311 C CD1   . LEU E 5 117 ? 149.758 105.563 117.691 1.00 4.96   ? 79  LEU S CD1   1 
ATOM   7312 C CD2   . LEU E 5 117 ? 149.607 104.319 115.530 1.00 0.70   ? 79  LEU S CD2   1 
ATOM   7313 N N     . PHE E 5 118 ? 153.348 104.571 118.645 1.00 12.55  ? 80  PHE S N     1 
ATOM   7314 C CA    . PHE E 5 118 ? 154.106 103.509 119.285 1.00 5.66   ? 80  PHE S CA    1 
ATOM   7315 C C     . PHE E 5 118 ? 153.168 102.437 119.818 1.00 9.11   ? 80  PHE S C     1 
ATOM   7316 O O     . PHE E 5 118 ? 152.118 102.747 120.391 1.00 13.79  ? 80  PHE S O     1 
ATOM   7317 C CB    . PHE E 5 118 ? 154.948 104.059 120.438 1.00 3.90   ? 80  PHE S CB    1 
ATOM   7318 C CG    . PHE E 5 118 ? 155.964 105.079 120.019 1.00 6.24   ? 80  PHE S CG    1 
ATOM   7319 C CD1   . PHE E 5 118 ? 157.105 104.698 119.337 1.00 11.43  ? 80  PHE S CD1   1 
ATOM   7320 C CD2   . PHE E 5 118 ? 155.790 106.416 120.331 1.00 11.44  ? 80  PHE S CD2   1 
ATOM   7321 C CE1   . PHE E 5 118 ? 158.044 105.634 118.960 1.00 12.73  ? 80  PHE S CE1   1 
ATOM   7322 C CE2   . PHE E 5 118 ? 156.725 107.354 119.960 1.00 11.81  ? 80  PHE S CE2   1 
ATOM   7323 C CZ    . PHE E 5 118 ? 157.853 106.965 119.275 1.00 11.84  ? 80  PHE S CZ    1 
ATOM   7324 N N     . LEU E 5 119 ? 153.562 101.178 119.641 1.00 11.61  ? 81  LEU S N     1 
ATOM   7325 C CA    . LEU E 5 119 ? 152.850 100.035 120.206 1.00 5.94   ? 81  LEU S CA    1 
ATOM   7326 C C     . LEU E 5 119 ? 153.876 99.121  120.864 1.00 9.32   ? 81  LEU S C     1 
ATOM   7327 O O     . LEU E 5 119 ? 154.651 98.454  120.172 1.00 6.25   ? 81  LEU S O     1 
ATOM   7328 C CB    . LEU E 5 119 ? 152.056 99.291  119.130 1.00 6.61   ? 81  LEU S CB    1 
ATOM   7329 C CG    . LEU E 5 119 ? 151.151 98.147  119.591 1.00 2.52   ? 81  LEU S CG    1 
ATOM   7330 C CD1   . LEU E 5 119 ? 149.899 98.696  120.250 1.00 1.17   ? 81  LEU S CD1   1 
ATOM   7331 C CD2   . LEU E 5 119 ? 150.782 97.251  118.419 1.00 0.48   ? 81  LEU S CD2   1 
ATOM   7332 N N     . GLN E 5 120 ? 153.895 99.102  122.194 1.00 14.02  ? 82  GLN S N     1 
ATOM   7333 C CA    . GLN E 5 120 ? 154.753 98.203  122.956 1.00 16.08  ? 82  GLN S CA    1 
ATOM   7334 C C     . GLN E 5 120 ? 153.960 96.952  123.305 1.00 12.55  ? 82  GLN S C     1 
ATOM   7335 O O     . GLN E 5 120 ? 152.904 97.041  123.940 1.00 20.78  ? 82  GLN S O     1 
ATOM   7336 C CB    . GLN E 5 120 ? 155.280 98.874  124.225 1.00 13.86  ? 82  GLN S CB    1 
ATOM   7337 C CG    . GLN E 5 120 ? 156.149 97.965  125.092 1.00 18.21  ? 82  GLN S CG    1 
ATOM   7338 C CD    . GLN E 5 120 ? 157.527 97.724  124.512 1.00 19.74  ? 82  GLN S CD    1 
ATOM   7339 O OE1   . GLN E 5 120 ? 158.272 98.663  124.240 1.00 10.33  ? 82  GLN S OE1   1 
ATOM   7340 N NE2   . GLN E 5 120 ? 157.874 96.458  124.319 1.00 20.13  ? 82  GLN S NE2   1 
ATOM   7341 N N     . MET E 5 121 ? 154.464 95.794  122.892 1.00 16.05  ? 83  MET S N     1 
ATOM   7342 C CA    . MET E 5 121 ? 153.808 94.518  123.131 1.00 20.74  ? 83  MET S CA    1 
ATOM   7343 C C     . MET E 5 121 ? 154.696 93.675  124.033 1.00 26.89  ? 83  MET S C     1 
ATOM   7344 O O     . MET E 5 121 ? 155.870 93.449  123.719 1.00 20.63  ? 83  MET S O     1 
ATOM   7345 C CB    . MET E 5 121 ? 153.532 93.798  121.812 1.00 21.81  ? 83  MET S CB    1 
ATOM   7346 C CG    . MET E 5 121 ? 152.868 94.677  120.766 1.00 17.93  ? 83  MET S CG    1 
ATOM   7347 S SD    . MET E 5 121 ? 152.961 93.960  119.120 1.00 20.57  ? 83  MET S SD    1 
ATOM   7348 C CE    . MET E 5 121 ? 154.731 93.989  118.866 1.00 21.18  ? 83  MET S CE    1 
ATOM   7349 N N     . THR E 5 122 ? 154.136 93.218  125.148 1.00 25.42  ? 84  THR S N     1 
ATOM   7350 C CA    . THR E 5 122 ? 154.849 92.410  126.123 1.00 22.80  ? 84  THR S CA    1 
ATOM   7351 C C     . THR E 5 122 ? 154.182 91.048  126.242 1.00 22.63  ? 84  THR S C     1 
ATOM   7352 O O     . THR E 5 122 ? 152.962 90.923  126.096 1.00 31.32  ? 84  THR S O     1 
ATOM   7353 C CB    . THR E 5 122 ? 154.886 93.092  127.497 1.00 23.22  ? 84  THR S CB    1 
ATOM   7354 O OG1   . THR E 5 122 ? 153.596 92.999  128.114 1.00 24.85  ? 84  THR S OG1   1 
ATOM   7355 C CG2   . THR E 5 122 ? 155.269 94.557  127.355 1.00 23.41  ? 84  THR S CG2   1 
ATOM   7356 N N     . SER E 5 123 ? 154.998 90.030  126.513 1.00 25.86  ? 85  SER S N     1 
ATOM   7357 C CA    . SER E 5 123 ? 154.538 88.646  126.622 1.00 23.40  ? 85  SER S CA    1 
ATOM   7358 C C     . SER E 5 123 ? 153.764 88.230  125.374 1.00 28.86  ? 85  SER S C     1 
ATOM   7359 O O     . SER E 5 123 ? 152.644 87.720  125.442 1.00 34.21  ? 85  SER S O     1 
ATOM   7360 C CB    . SER E 5 123 ? 153.699 88.443  127.886 1.00 24.68  ? 85  SER S CB    1 
ATOM   7361 O OG    . SER E 5 123 ? 152.460 89.123  127.795 1.00 29.54  ? 85  SER S OG    1 
ATOM   7362 N N     . LEU E 5 124 ? 154.379 88.466  124.216 1.00 26.36  ? 86  LEU S N     1 
ATOM   7363 C CA    . LEU E 5 124 ? 153.740 88.162  122.943 1.00 25.54  ? 86  LEU S CA    1 
ATOM   7364 C C     . LEU E 5 124 ? 153.457 86.670  122.823 1.00 26.54  ? 86  LEU S C     1 
ATOM   7365 O O     . LEU E 5 124 ? 154.318 85.835  123.116 1.00 36.75  ? 86  LEU S O     1 
ATOM   7366 C CB    . LEU E 5 124 ? 154.626 88.629  121.788 1.00 25.42  ? 86  LEU S CB    1 
ATOM   7367 C CG    . LEU E 5 124 ? 154.511 90.107  121.412 1.00 26.81  ? 86  LEU S CG    1 
ATOM   7368 C CD1   . LEU E 5 124 ? 155.742 90.565  120.647 1.00 29.81  ? 86  LEU S CD1   1 
ATOM   7369 C CD2   . LEU E 5 124 ? 153.251 90.355  120.602 1.00 22.29  ? 86  LEU S CD2   1 
ATOM   7370 N N     . ARG E 5 125 ? 152.247 86.341  122.389 1.00 24.14  ? 87  ARG S N     1 
ATOM   7371 C CA    . ARG E 5 125 ? 151.810 84.963  122.236 1.00 22.84  ? 87  ARG S CA    1 
ATOM   7372 C C     . ARG E 5 125 ? 151.925 84.525  120.780 1.00 26.35  ? 87  ARG S C     1 
ATOM   7373 O O     . ARG E 5 125 ? 152.219 85.318  119.883 1.00 31.09  ? 87  ARG S O     1 
ATOM   7374 C CB    . ARG E 5 125 ? 150.372 84.800  122.736 1.00 21.75  ? 87  ARG S CB    1 
ATOM   7375 C CG    . ARG E 5 125 ? 150.235 84.867  124.248 1.00 30.20  ? 87  ARG S CG    1 
ATOM   7376 C CD    . ARG E 5 125 ? 148.844 84.457  124.701 1.00 32.20  ? 87  ARG S CD    1 
ATOM   7377 N NE    . ARG E 5 125 ? 147.960 85.606  124.856 1.00 31.61  ? 87  ARG S NE    1 
ATOM   7378 C CZ    . ARG E 5 125 ? 146.953 85.893  124.042 1.00 29.76  ? 87  ARG S CZ    1 
ATOM   7379 N NH1   . ARG E 5 125 ? 146.675 85.135  122.994 1.00 27.46  ? 87  ARG S NH1   1 
ATOM   7380 N NH2   . ARG E 5 125 ? 146.207 86.966  124.286 1.00 24.60  ? 87  ARG S NH2   1 
ATOM   7381 N N     . SER E 5 126 ? 151.689 83.231  120.553 1.00 28.33  ? 88  SER S N     1 
ATOM   7382 C CA    . SER E 5 126 ? 151.748 82.696  119.197 1.00 27.14  ? 88  SER S CA    1 
ATOM   7383 C C     . SER E 5 126 ? 150.620 83.236  118.327 1.00 23.84  ? 88  SER S C     1 
ATOM   7384 O O     . SER E 5 126 ? 150.752 83.276  117.099 1.00 23.07  ? 88  SER S O     1 
ATOM   7385 C CB    . SER E 5 126 ? 151.706 81.168  119.232 1.00 22.14  ? 88  SER S CB    1 
ATOM   7386 N N     . GLU E 5 127 ? 149.512 83.654  118.939 1.00 22.84  ? 89  GLU S N     1 
ATOM   7387 C CA    . GLU E 5 127 ? 148.377 84.183  118.196 1.00 25.65  ? 89  GLU S CA    1 
ATOM   7388 C C     . GLU E 5 127 ? 148.591 85.613  117.719 1.00 28.35  ? 89  GLU S C     1 
ATOM   7389 O O     . GLU E 5 127 ? 147.768 86.119  116.948 1.00 26.01  ? 89  GLU S O     1 
ATOM   7390 C CB    . GLU E 5 127 ? 147.111 84.115  119.054 1.00 21.49  ? 89  GLU S CB    1 
ATOM   7391 C CG    . GLU E 5 127 ? 146.682 82.703  119.419 1.00 27.24  ? 89  GLU S CG    1 
ATOM   7392 C CD    . GLU E 5 127 ? 147.292 82.224  120.723 1.00 36.09  ? 89  GLU S CD    1 
ATOM   7393 O OE1   . GLU E 5 127 ? 147.253 82.984  121.713 1.00 38.59  ? 89  GLU S OE1   1 
ATOM   7394 O OE2   . GLU E 5 127 ? 147.808 81.088  120.757 1.00 34.77  ? 89  GLU S OE2   1 
ATOM   7395 N N     . ASP E 5 128 ? 149.662 86.272  118.153 1.00 26.31  ? 90  ASP S N     1 
ATOM   7396 C CA    . ASP E 5 128 ? 149.939 87.649  117.771 1.00 15.63  ? 90  ASP S CA    1 
ATOM   7397 C C     . ASP E 5 128 ? 150.690 87.763  116.450 1.00 27.85  ? 90  ASP S C     1 
ATOM   7398 O O     . ASP E 5 128 ? 150.955 88.883  116.002 1.00 27.75  ? 90  ASP S O     1 
ATOM   7399 C CB    . ASP E 5 128 ? 150.733 88.350  118.877 1.00 9.73   ? 90  ASP S CB    1 
ATOM   7400 C CG    . ASP E 5 128 ? 149.969 88.423  120.183 1.00 17.39  ? 90  ASP S CG    1 
ATOM   7401 O OD1   . ASP E 5 128 ? 148.737 88.620  120.142 1.00 25.10  ? 90  ASP S OD1   1 
ATOM   7402 O OD2   . ASP E 5 128 ? 150.599 88.281  121.252 1.00 24.54  ? 90  ASP S OD2   1 
ATOM   7403 N N     . THR E 5 129 ? 151.043 86.642  115.825 1.00 28.66  ? 91  THR S N     1 
ATOM   7404 C CA    . THR E 5 129 ? 151.715 86.661  114.529 1.00 23.66  ? 91  THR S CA    1 
ATOM   7405 C C     . THR E 5 129 ? 150.758 87.204  113.475 1.00 19.99  ? 91  THR S C     1 
ATOM   7406 O O     . THR E 5 129 ? 149.783 86.538  113.113 1.00 21.87  ? 91  THR S O     1 
ATOM   7407 C CB    . THR E 5 129 ? 152.192 85.259  114.162 1.00 29.33  ? 91  THR S CB    1 
ATOM   7408 O OG1   . THR E 5 129 ? 153.248 84.864  115.046 1.00 32.72  ? 91  THR S OG1   1 
ATOM   7409 C CG2   . THR E 5 129 ? 152.692 85.218  112.725 1.00 23.51  ? 91  THR S CG2   1 
ATOM   7410 N N     . ALA E 5 130 ? 151.033 88.408  112.981 1.00 21.48  ? 92  ALA S N     1 
ATOM   7411 C CA    . ALA E 5 130 ? 150.139 89.073  112.041 1.00 19.58  ? 92  ALA S CA    1 
ATOM   7412 C C     . ALA E 5 130 ? 150.854 90.283  111.457 1.00 13.02  ? 92  ALA S C     1 
ATOM   7413 O O     . ALA E 5 130 ? 151.928 90.677  111.918 1.00 21.35  ? 92  ALA S O     1 
ATOM   7414 C CB    . ALA E 5 130 ? 148.829 89.494  112.713 1.00 14.83  ? 92  ALA S CB    1 
ATOM   7415 N N     . MET E 5 131 ? 150.247 90.865  110.427 1.00 13.48  ? 93  MET S N     1 
ATOM   7416 C CA    . MET E 5 131 ? 150.703 92.132  109.878 1.00 11.30  ? 93  MET S CA    1 
ATOM   7417 C C     . MET E 5 131 ? 149.962 93.268  110.572 1.00 8.37   ? 93  MET S C     1 
ATOM   7418 O O     . MET E 5 131 ? 148.730 93.264  110.641 1.00 12.67  ? 93  MET S O     1 
ATOM   7419 C CB    . MET E 5 131 ? 150.476 92.191  108.368 1.00 7.95   ? 93  MET S CB    1 
ATOM   7420 C CG    . MET E 5 131 ? 150.792 93.545  107.753 1.00 14.69  ? 93  MET S CG    1 
ATOM   7421 S SD    . MET E 5 131 ? 150.989 93.483  105.963 1.00 47.78  ? 93  MET S SD    1 
ATOM   7422 C CE    . MET E 5 131 ? 152.689 92.939  105.828 1.00 17.36  ? 93  MET S CE    1 
ATOM   7423 N N     . TYR E 5 132 ? 150.719 94.229  111.088 1.00 6.55   ? 94  TYR S N     1 
ATOM   7424 C CA    . TYR E 5 132 ? 150.179 95.344  111.850 1.00 2.29   ? 94  TYR S CA    1 
ATOM   7425 C C     . TYR E 5 132 ? 150.142 96.589  110.975 1.00 5.65   ? 94  TYR S C     1 
ATOM   7426 O O     . TYR E 5 132 ? 151.120 96.894  110.281 1.00 11.97  ? 94  TYR S O     1 
ATOM   7427 C CB    . TYR E 5 132 ? 151.019 95.607  113.102 1.00 11.89  ? 94  TYR S CB    1 
ATOM   7428 C CG    . TYR E 5 132 ? 150.865 94.565  114.187 1.00 13.29  ? 94  TYR S CG    1 
ATOM   7429 C CD1   . TYR E 5 132 ? 151.370 93.282  114.022 1.00 11.44  ? 94  TYR S CD1   1 
ATOM   7430 C CD2   . TYR E 5 132 ? 150.224 94.868  115.380 1.00 12.40  ? 94  TYR S CD2   1 
ATOM   7431 C CE1   . TYR E 5 132 ? 151.234 92.328  115.011 1.00 12.27  ? 94  TYR S CE1   1 
ATOM   7432 C CE2   . TYR E 5 132 ? 150.086 93.921  116.376 1.00 14.03  ? 94  TYR S CE2   1 
ATOM   7433 C CZ    . TYR E 5 132 ? 150.592 92.653  116.185 1.00 11.97  ? 94  TYR S CZ    1 
ATOM   7434 O OH    . TYR E 5 132 ? 150.455 91.705  117.172 1.00 7.69   ? 94  TYR S OH    1 
ATOM   7435 N N     . TYR E 5 133 ? 149.014 97.295  111.009 1.00 5.13   ? 95  TYR S N     1 
ATOM   7436 C CA    . TYR E 5 133 ? 148.830 98.546  110.287 1.00 4.61   ? 95  TYR S CA    1 
ATOM   7437 C C     . TYR E 5 133 ? 148.499 99.652  111.277 1.00 0.42   ? 95  TYR S C     1 
ATOM   7438 O O     . TYR E 5 133 ? 147.707 99.444  112.205 1.00 7.04   ? 95  TYR S O     1 
ATOM   7439 C CB    . TYR E 5 133 ? 147.706 98.442  109.251 1.00 1.79   ? 95  TYR S CB    1 
ATOM   7440 C CG    . TYR E 5 133 ? 147.755 97.219  108.366 1.00 5.06   ? 95  TYR S CG    1 
ATOM   7441 C CD1   . TYR E 5 133 ? 148.526 97.203  107.214 1.00 3.40   ? 95  TYR S CD1   1 
ATOM   7442 C CD2   . TYR E 5 133 ? 147.014 96.087  108.674 1.00 11.88  ? 95  TYR S CD2   1 
ATOM   7443 C CE1   . TYR E 5 133 ? 148.567 96.091  106.398 1.00 9.34   ? 95  TYR S CE1   1 
ATOM   7444 C CE2   . TYR E 5 133 ? 147.049 94.970  107.865 1.00 13.80  ? 95  TYR S CE2   1 
ATOM   7445 C CZ    . TYR E 5 133 ? 147.826 94.978  106.728 1.00 12.05  ? 95  TYR S CZ    1 
ATOM   7446 O OH    . TYR E 5 133 ? 147.864 93.867  105.919 1.00 13.46  ? 95  TYR S OH    1 
ATOM   7447 N N     . CYS E 5 134 ? 149.105 100.821 111.079 1.00 1.59   ? 96  CYS S N     1 
ATOM   7448 C CA    . CYS E 5 134 ? 148.689 102.030 111.776 1.00 9.28   ? 96  CYS S CA    1 
ATOM   7449 C C     . CYS E 5 134 ? 147.723 102.794 110.880 1.00 0.57   ? 96  CYS S C     1 
ATOM   7450 O O     . CYS E 5 134 ? 148.036 103.088 109.722 1.00 0.67   ? 96  CYS S O     1 
ATOM   7451 C CB    . CYS E 5 134 ? 149.889 102.903 112.153 1.00 0.00   ? 96  CYS S CB    1 
ATOM   7452 S SG    . CYS E 5 134 ? 151.024 103.308 110.807 1.00 40.99  ? 96  CYS S SG    1 
ATOM   7453 N N     . VAL E 5 135 ? 146.548 103.101 111.417 1.00 0.00   ? 97  VAL S N     1 
ATOM   7454 C CA    . VAL E 5 135 ? 145.441 103.664 110.657 1.00 0.00   ? 97  VAL S CA    1 
ATOM   7455 C C     . VAL E 5 135 ? 145.165 105.064 111.180 1.00 0.00   ? 97  VAL S C     1 
ATOM   7456 O O     . VAL E 5 135 ? 144.908 105.249 112.377 1.00 0.00   ? 97  VAL S O     1 
ATOM   7457 C CB    . VAL E 5 135 ? 144.180 102.789 110.752 1.00 0.43   ? 97  VAL S CB    1 
ATOM   7458 C CG1   . VAL E 5 135 ? 143.135 103.256 109.755 1.00 0.00   ? 97  VAL S CG1   1 
ATOM   7459 C CG2   . VAL E 5 135 ? 144.528 101.327 110.527 1.00 0.00   ? 97  VAL S CG2   1 
ATOM   7460 N N     . ARG E 5 136 ? 145.229 106.043 110.284 1.00 1.70   ? 98  ARG S N     1 
ATOM   7461 C CA    . ARG E 5 136 ? 144.837 107.410 110.586 1.00 0.00   ? 98  ARG S CA    1 
ATOM   7462 C C     . ARG E 5 136 ? 143.316 107.510 110.607 1.00 1.75   ? 98  ARG S C     1 
ATOM   7463 O O     . ARG E 5 136 ? 142.635 106.944 109.747 1.00 12.05  ? 98  ARG S O     1 
ATOM   7464 C CB    . ARG E 5 136 ? 145.436 108.349 109.536 1.00 0.00   ? 98  ARG S CB    1 
ATOM   7465 C CG    . ARG E 5 136 ? 144.939 109.771 109.564 1.00 14.32  ? 98  ARG S CG    1 
ATOM   7466 C CD    . ARG E 5 136 ? 143.863 110.011 108.515 1.00 6.38   ? 98  ARG S CD    1 
ATOM   7467 N NE    . ARG E 5 136 ? 144.368 109.977 107.148 1.00 0.00   ? 98  ARG S NE    1 
ATOM   7468 C CZ    . ARG E 5 136 ? 144.769 111.045 106.471 1.00 4.91   ? 98  ARG S CZ    1 
ATOM   7469 N NH1   . ARG E 5 136 ? 144.777 112.248 107.019 1.00 2.86   ? 98  ARG S NH1   1 
ATOM   7470 N NH2   . ARG E 5 136 ? 145.163 110.902 105.210 1.00 25.37  ? 98  ARG S NH2   1 
ATOM   7471 N N     . SER E 5 137 ? 142.775 108.233 111.591 1.00 0.96   ? 99  SER S N     1 
ATOM   7472 C CA    . SER E 5 137 ? 141.324 108.282 111.756 1.00 0.70   ? 99  SER S CA    1 
ATOM   7473 C C     . SER E 5 137 ? 140.950 109.532 112.543 1.00 0.00   ? 99  SER S C     1 
ATOM   7474 O O     . SER E 5 137 ? 141.248 109.619 113.737 1.00 11.99  ? 99  SER S O     1 
ATOM   7475 C CB    . SER E 5 137 ? 140.836 107.021 112.461 1.00 0.00   ? 99  SER S CB    1 
ATOM   7476 O OG    . SER E 5 137 ? 139.469 107.113 112.800 1.00 6.91   ? 99  SER S OG    1 
ATOM   7477 N N     . ILE E 5 138 ? 140.279 110.480 111.886 1.00 0.00   ? 100 ILE S N     1 
ATOM   7478 C CA    . ILE E 5 138 ? 139.852 111.725 112.515 1.00 0.00   ? 100 ILE S CA    1 
ATOM   7479 C C     . ILE E 5 138 ? 138.347 111.671 112.732 1.00 1.79   ? 100 ILE S C     1 
ATOM   7480 O O     . ILE E 5 138 ? 137.618 110.987 112.005 1.00 6.21   ? 100 ILE S O     1 
ATOM   7481 C CB    . ILE E 5 138 ? 140.259 112.949 111.666 1.00 0.03   ? 100 ILE S CB    1 
ATOM   7482 C CG1   . ILE E 5 138 ? 140.058 114.254 112.439 1.00 1.12   ? 100 ILE S CG1   1 
ATOM   7483 C CG2   . ILE E 5 138 ? 139.497 112.973 110.347 1.00 0.00   ? 100 ILE S CG2   1 
ATOM   7484 C CD1   . ILE E 5 138 ? 140.741 115.440 111.803 1.00 0.00   ? 100 ILE S CD1   1 
ATOM   7485 N N     . TYR E 5 139 ? 137.871 112.397 113.742 1.00 2.30   ? 101 TYR S N     1 
ATOM   7486 C CA    . TYR E 5 139 ? 136.470 112.323 114.148 1.00 1.23   ? 101 TYR S CA    1 
ATOM   7487 C C     . TYR E 5 139 ? 135.916 113.726 114.350 1.00 9.32   ? 101 TYR S C     1 
ATOM   7488 O O     . TYR E 5 139 ? 136.263 114.402 115.324 1.00 3.04   ? 101 TYR S O     1 
ATOM   7489 C CB    . TYR E 5 139 ? 136.316 111.498 115.422 1.00 0.00   ? 101 TYR S CB    1 
ATOM   7490 C CG    . TYR E 5 139 ? 136.709 110.049 115.267 1.00 0.00   ? 101 TYR S CG    1 
ATOM   7491 C CD1   . TYR E 5 139 ? 135.826 109.124 114.731 1.00 0.00   ? 101 TYR S CD1   1 
ATOM   7492 C CD2   . TYR E 5 139 ? 137.967 109.608 115.652 1.00 0.00   ? 101 TYR S CD2   1 
ATOM   7493 C CE1   . TYR E 5 139 ? 136.182 107.801 114.587 1.00 0.00   ? 101 TYR S CE1   1 
ATOM   7494 C CE2   . TYR E 5 139 ? 138.332 108.287 115.510 1.00 0.00   ? 101 TYR S CE2   1 
ATOM   7495 C CZ    . TYR E 5 139 ? 137.436 107.388 114.978 1.00 0.29   ? 101 TYR S CZ    1 
ATOM   7496 O OH    . TYR E 5 139 ? 137.798 106.069 114.835 1.00 8.96   ? 101 TYR S OH    1 
ATOM   7497 N N     . TYR E 5 140 ? 135.057 114.154 113.430 1.00 2.49   ? 102 TYR S N     1 
ATOM   7498 C CA    . TYR E 5 140 ? 134.202 115.317 113.615 1.00 0.00   ? 102 TYR S CA    1 
ATOM   7499 C C     . TYR E 5 140 ? 132.967 115.106 112.752 1.00 5.05   ? 102 TYR S C     1 
ATOM   7500 O O     . TYR E 5 140 ? 132.837 114.088 112.066 1.00 5.84   ? 102 TYR S O     1 
ATOM   7501 C CB    . TYR E 5 140 ? 134.930 116.625 113.275 1.00 0.44   ? 102 TYR S CB    1 
ATOM   7502 C CG    . TYR E 5 140 ? 135.620 116.638 111.930 1.00 1.86   ? 102 TYR S CG    1 
ATOM   7503 C CD1   . TYR E 5 140 ? 134.926 116.967 110.774 1.00 0.35   ? 102 TYR S CD1   1 
ATOM   7504 C CD2   . TYR E 5 140 ? 136.969 116.334 111.819 1.00 0.00   ? 102 TYR S CD2   1 
ATOM   7505 C CE1   . TYR E 5 140 ? 135.552 116.983 109.545 1.00 0.00   ? 102 TYR S CE1   1 
ATOM   7506 C CE2   . TYR E 5 140 ? 137.603 116.349 110.594 1.00 0.00   ? 102 TYR S CE2   1 
ATOM   7507 C CZ    . TYR E 5 140 ? 136.891 116.673 109.461 1.00 1.45   ? 102 TYR S CZ    1 
ATOM   7508 O OH    . TYR E 5 140 ? 137.522 116.689 108.239 1.00 11.51  ? 102 TYR S OH    1 
ATOM   7509 N N     . TYR E 5 141 ? 132.047 116.065 112.792 1.00 0.00   ? 103 TYR S N     1 
ATOM   7510 C CA    . TYR E 5 141 ? 130.829 115.938 112.002 1.00 1.45   ? 103 TYR S CA    1 
ATOM   7511 C C     . TYR E 5 141 ? 131.165 115.932 110.517 1.00 0.87   ? 103 TYR S C     1 
ATOM   7512 O O     . TYR E 5 141 ? 131.763 116.881 110.001 1.00 3.75   ? 103 TYR S O     1 
ATOM   7513 C CB    . TYR E 5 141 ? 129.855 117.070 112.320 1.00 0.00   ? 103 TYR S CB    1 
ATOM   7514 C CG    . TYR E 5 141 ? 128.613 117.024 111.461 1.00 0.00   ? 103 TYR S CG    1 
ATOM   7515 C CD1   . TYR E 5 141 ? 127.640 116.057 111.668 1.00 0.00   ? 103 TYR S CD1   1 
ATOM   7516 C CD2   . TYR E 5 141 ? 128.424 117.932 110.429 1.00 0.56   ? 103 TYR S CD2   1 
ATOM   7517 C CE1   . TYR E 5 141 ? 126.508 116.003 110.879 1.00 0.60   ? 103 TYR S CE1   1 
ATOM   7518 C CE2   . TYR E 5 141 ? 127.297 117.886 109.636 1.00 0.52   ? 103 TYR S CE2   1 
ATOM   7519 C CZ    . TYR E 5 141 ? 126.342 116.920 109.864 1.00 5.38   ? 103 TYR S CZ    1 
ATOM   7520 O OH    . TYR E 5 141 ? 125.216 116.873 109.075 1.00 16.97  ? 103 TYR S OH    1 
ATOM   7521 N N     . GLY E 5 142 ? 130.777 114.859 109.831 1.00 1.45   ? 104 GLY S N     1 
ATOM   7522 C CA    . GLY E 5 142 ? 131.052 114.725 108.417 1.00 0.00   ? 104 GLY S CA    1 
ATOM   7523 C C     . GLY E 5 142 ? 132.446 114.254 108.074 1.00 2.69   ? 104 GLY S C     1 
ATOM   7524 O O     . GLY E 5 142 ? 132.801 114.238 106.891 1.00 7.60   ? 104 GLY S O     1 
ATOM   7525 N N     . SER E 5 143 ? 133.246 113.871 109.065 1.00 3.57   ? 105 SER S N     1 
ATOM   7526 C CA    . SER E 5 143 ? 134.606 113.429 108.807 1.00 0.16   ? 105 SER S CA    1 
ATOM   7527 C C     . SER E 5 143 ? 134.608 112.039 108.172 1.00 2.28   ? 105 SER S C     1 
ATOM   7528 O O     . SER E 5 143 ? 133.584 111.355 108.090 1.00 7.18   ? 105 SER S O     1 
ATOM   7529 C CB    . SER E 5 143 ? 135.422 113.423 110.099 1.00 0.00   ? 105 SER S CB    1 
ATOM   7530 O OG    . SER E 5 143 ? 135.019 112.368 110.953 1.00 0.00   ? 105 SER S OG    1 
ATOM   7531 N N     . SER E 5 144 ? 135.789 111.622 107.723 1.00 4.16   ? 106 SER S N     1 
ATOM   7532 C CA    . SER E 5 144 ? 135.988 110.329 107.071 1.00 0.00   ? 106 SER S CA    1 
ATOM   7533 C C     . SER E 5 144 ? 137.088 109.581 107.810 1.00 0.00   ? 106 SER S C     1 
ATOM   7534 O O     . SER E 5 144 ? 138.243 109.552 107.366 1.00 4.76   ? 106 SER S O     1 
ATOM   7535 C CB    . SER E 5 144 ? 136.335 110.501 105.593 1.00 3.30   ? 106 SER S CB    1 
ATOM   7536 O OG    . SER E 5 144 ? 136.448 109.245 104.948 1.00 12.97  ? 106 SER S OG    1 
ATOM   7537 N N     . PRO E 5 145 ? 136.768 108.971 108.947 1.00 2.96   ? 107 PRO S N     1 
ATOM   7538 C CA    . PRO E 5 145 ? 137.781 108.216 109.689 1.00 3.98   ? 107 PRO S CA    1 
ATOM   7539 C C     . PRO E 5 145 ? 138.163 106.931 108.971 1.00 4.11   ? 107 PRO S C     1 
ATOM   7540 O O     . PRO E 5 145 ? 137.460 106.445 108.083 1.00 2.25   ? 107 PRO S O     1 
ATOM   7541 C CB    . PRO E 5 145 ? 137.098 107.922 111.029 1.00 0.00   ? 107 PRO S CB    1 
ATOM   7542 C CG    . PRO E 5 145 ? 135.656 108.020 110.755 1.00 0.00   ? 107 PRO S CG    1 
ATOM   7543 C CD    . PRO E 5 145 ? 135.476 109.011 109.651 1.00 4.02   ? 107 PRO S CD    1 
ATOM   7544 N N     . PHE E 5 146 ? 139.318 106.390 109.370 1.00 1.81   ? 108 PHE S N     1 
ATOM   7545 C CA    . PHE E 5 146 ? 139.870 105.158 108.803 1.00 0.00   ? 108 PHE S CA    1 
ATOM   7546 C C     . PHE E 5 146 ? 140.155 105.297 107.310 1.00 0.00   ? 108 PHE S C     1 
ATOM   7547 O O     . PHE E 5 146 ? 140.106 104.316 106.566 1.00 8.61   ? 108 PHE S O     1 
ATOM   7548 C CB    . PHE E 5 146 ? 138.943 103.963 109.052 1.00 2.79   ? 108 PHE S CB    1 
ATOM   7549 C CG    . PHE E 5 146 ? 139.183 103.266 110.359 1.00 7.60   ? 108 PHE S CG    1 
ATOM   7550 C CD1   . PHE E 5 146 ? 138.726 103.811 111.545 1.00 5.96   ? 108 PHE S CD1   1 
ATOM   7551 C CD2   . PHE E 5 146 ? 139.856 102.057 110.400 1.00 3.84   ? 108 PHE S CD2   1 
ATOM   7552 C CE1   . PHE E 5 146 ? 138.942 103.168 112.746 1.00 4.16   ? 108 PHE S CE1   1 
ATOM   7553 C CE2   . PHE E 5 146 ? 140.076 101.410 111.598 1.00 0.00   ? 108 PHE S CE2   1 
ATOM   7554 C CZ    . PHE E 5 146 ? 139.619 101.966 112.772 1.00 0.00   ? 108 PHE S CZ    1 
ATOM   7555 N N     . ASP E 5 147 ? 140.464 106.514 106.859 1.00 0.33   ? 109 ASP S N     1 
ATOM   7556 C CA    . ASP E 5 147 ? 140.637 106.771 105.436 1.00 0.00   ? 109 ASP S CA    1 
ATOM   7557 C C     . ASP E 5 147 ? 142.034 106.455 104.921 1.00 8.68   ? 109 ASP S C     1 
ATOM   7558 O O     . ASP E 5 147 ? 142.209 106.316 103.705 1.00 10.31  ? 109 ASP S O     1 
ATOM   7559 C CB    . ASP E 5 147 ? 140.306 108.232 105.116 1.00 0.00   ? 109 ASP S CB    1 
ATOM   7560 C CG    . ASP E 5 147 ? 140.934 109.198 106.095 1.00 8.68   ? 109 ASP S CG    1 
ATOM   7561 O OD1   . ASP E 5 147 ? 141.320 108.754 107.195 1.00 4.46   ? 109 ASP S OD1   1 
ATOM   7562 O OD2   . ASP E 5 147 ? 141.042 110.397 105.766 1.00 8.31   ? 109 ASP S OD2   1 
ATOM   7563 N N     . PHE E 5 148 ? 143.028 106.334 105.798 1.00 0.00   ? 110 PHE S N     1 
ATOM   7564 C CA    . PHE E 5 148 ? 144.383 106.014 105.374 1.00 0.00   ? 110 PHE S CA    1 
ATOM   7565 C C     . PHE E 5 148 ? 144.957 104.908 106.244 1.00 0.00   ? 110 PHE S C     1 
ATOM   7566 O O     . PHE E 5 148 ? 144.815 104.929 107.469 1.00 0.00   ? 110 PHE S O     1 
ATOM   7567 C CB    . PHE E 5 148 ? 145.299 107.240 105.426 1.00 4.18   ? 110 PHE S CB    1 
ATOM   7568 C CG    . PHE E 5 148 ? 146.593 107.052 104.690 1.00 2.80   ? 110 PHE S CG    1 
ATOM   7569 C CD1   . PHE E 5 148 ? 146.634 107.120 103.308 1.00 0.97   ? 110 PHE S CD1   1 
ATOM   7570 C CD2   . PHE E 5 148 ? 147.764 106.788 105.377 1.00 8.22   ? 110 PHE S CD2   1 
ATOM   7571 C CE1   . PHE E 5 148 ? 147.821 106.939 102.628 1.00 6.69   ? 110 PHE S CE1   1 
ATOM   7572 C CE2   . PHE E 5 148 ? 148.953 106.606 104.702 1.00 6.78   ? 110 PHE S CE2   1 
ATOM   7573 C CZ    . PHE E 5 148 ? 148.982 106.682 103.327 1.00 7.85   ? 110 PHE S CZ    1 
ATOM   7574 N N     . TRP E 5 149 ? 145.613 103.948 105.597 1.00 5.14   ? 111 TRP S N     1 
ATOM   7575 C CA    . TRP E 5 149 ? 146.230 102.813 106.266 1.00 0.00   ? 111 TRP S CA    1 
ATOM   7576 C C     . TRP E 5 149 ? 147.701 102.746 105.889 1.00 1.71   ? 111 TRP S C     1 
ATOM   7577 O O     . TRP E 5 149 ? 148.063 102.970 104.730 1.00 20.08  ? 111 TRP S O     1 
ATOM   7578 C CB    . TRP E 5 149 ? 145.545 101.492 105.886 1.00 3.64   ? 111 TRP S CB    1 
ATOM   7579 C CG    . TRP E 5 149 ? 144.143 101.347 106.392 1.00 0.44   ? 111 TRP S CG    1 
ATOM   7580 C CD1   . TRP E 5 149 ? 143.112 102.224 106.224 1.00 0.00   ? 111 TRP S CD1   1 
ATOM   7581 C CD2   . TRP E 5 149 ? 143.615 100.247 107.141 1.00 2.76   ? 111 TRP S CD2   1 
ATOM   7582 N NE1   . TRP E 5 149 ? 141.977 101.742 106.826 1.00 0.00   ? 111 TRP S NE1   1 
ATOM   7583 C CE2   . TRP E 5 149 ? 142.259 100.529 107.396 1.00 2.92   ? 111 TRP S CE2   1 
ATOM   7584 C CE3   . TRP E 5 149 ? 144.158 99.052  107.622 1.00 0.70   ? 111 TRP S CE3   1 
ATOM   7585 C CZ2   . TRP E 5 149 ? 141.439 99.660  108.112 1.00 0.00   ? 111 TRP S CZ2   1 
ATOM   7586 C CZ3   . TRP E 5 149 ? 143.342 98.192  108.331 1.00 1.03   ? 111 TRP S CZ3   1 
ATOM   7587 C CH2   . TRP E 5 149 ? 141.997 98.500  108.569 1.00 0.00   ? 111 TRP S CH2   1 
ATOM   7588 N N     . GLY E 5 150 ? 148.544 102.439 106.870 1.00 9.48   ? 112 GLY S N     1 
ATOM   7589 C CA    . GLY E 5 150 ? 149.947 102.228 106.597 1.00 1.34   ? 112 GLY S CA    1 
ATOM   7590 C C     . GLY E 5 150 ? 150.206 100.883 105.945 1.00 4.90   ? 112 GLY S C     1 
ATOM   7591 O O     . GLY E 5 150 ? 149.339 100.014 105.878 1.00 14.73  ? 112 GLY S O     1 
ATOM   7592 N N     . GLN E 5 151 ? 151.436 100.720 105.453 1.00 4.02   ? 113 GLN S N     1 
ATOM   7593 C CA    . GLN E 5 151 ? 151.803 99.474  104.787 1.00 11.69  ? 113 GLN S CA    1 
ATOM   7594 C C     . GLN E 5 151 ? 151.783 98.291  105.747 1.00 19.03  ? 113 GLN S C     1 
ATOM   7595 O O     . GLN E 5 151 ? 151.379 97.189  105.360 1.00 20.09  ? 113 GLN S O     1 
ATOM   7596 C CB    . GLN E 5 151 ? 153.177 99.613  104.135 1.00 14.09  ? 113 GLN S CB    1 
ATOM   7597 C CG    . GLN E 5 151 ? 153.224 100.639 103.015 1.00 18.14  ? 113 GLN S CG    1 
ATOM   7598 C CD    . GLN E 5 151 ? 152.179 100.384 101.946 1.00 23.20  ? 113 GLN S CD    1 
ATOM   7599 O OE1   . GLN E 5 151 ? 151.947 99.243  101.546 1.00 23.22  ? 113 GLN S OE1   1 
ATOM   7600 N NE2   . GLN E 5 151 ? 151.539 101.449 101.479 1.00 19.78  ? 113 GLN S NE2   1 
ATOM   7601 N N     . GLY E 5 152 ? 152.212 98.492  106.982 1.00 19.57  ? 114 GLY S N     1 
ATOM   7602 C CA    . GLY E 5 152 ? 152.176 97.436  107.981 1.00 8.18   ? 114 GLY S CA    1 
ATOM   7603 C C     . GLY E 5 152 ? 153.458 96.633  108.022 1.00 22.60  ? 114 GLY S C     1 
ATOM   7604 O O     . GLY E 5 152 ? 154.208 96.543  107.050 1.00 27.54  ? 114 GLY S O     1 
ATOM   7605 N N     . THR E 5 153 ? 153.716 96.034  109.181 1.00 20.63  ? 115 THR S N     1 
ATOM   7606 C CA    . THR E 5 153 ? 154.883 95.186  109.383 1.00 18.12  ? 115 THR S CA    1 
ATOM   7607 C C     . THR E 5 153 ? 154.452 93.821  109.894 1.00 17.98  ? 115 THR S C     1 
ATOM   7608 O O     . THR E 5 153 ? 153.513 93.713  110.685 1.00 15.58  ? 115 THR S O     1 
ATOM   7609 C CB    . THR E 5 153 ? 155.877 95.811  110.368 1.00 22.76  ? 115 THR S CB    1 
ATOM   7610 O OG1   . THR E 5 153 ? 155.201 96.163  111.582 1.00 20.05  ? 115 THR S OG1   1 
ATOM   7611 C CG2   . THR E 5 153 ? 156.535 97.034  109.761 1.00 20.13  ? 115 THR S CG2   1 
ATOM   7612 N N     . THR E 5 154 ? 155.145 92.782  109.436 1.00 20.49  ? 116 THR S N     1 
ATOM   7613 C CA    . THR E 5 154 ? 154.829 91.415  109.820 1.00 16.41  ? 116 THR S CA    1 
ATOM   7614 C C     . THR E 5 154 ? 155.560 91.053  111.105 1.00 20.63  ? 116 THR S C     1 
ATOM   7615 O O     . THR E 5 154 ? 156.785 91.185  111.190 1.00 30.73  ? 116 THR S O     1 
ATOM   7616 C CB    . THR E 5 154 ? 155.210 90.438  108.706 1.00 18.65  ? 116 THR S CB    1 
ATOM   7617 O OG1   . THR E 5 154 ? 154.581 90.838  107.482 1.00 25.74  ? 116 THR S OG1   1 
ATOM   7618 C CG2   . THR E 5 154 ? 154.763 89.028  109.060 1.00 19.96  ? 116 THR S CG2   1 
ATOM   7619 N N     . LEU E 5 155 ? 154.805 90.605  112.103 1.00 18.85  ? 117 LEU S N     1 
ATOM   7620 C CA    . LEU E 5 155 ? 155.348 90.102  113.356 1.00 23.78  ? 117 LEU S CA    1 
ATOM   7621 C C     . LEU E 5 155 ? 155.081 88.606  113.416 1.00 30.03  ? 117 LEU S C     1 
ATOM   7622 O O     . LEU E 5 155 ? 153.922 88.178  113.354 1.00 36.60  ? 117 LEU S O     1 
ATOM   7623 C CB    . LEU E 5 155 ? 154.709 90.806  114.551 1.00 25.76  ? 117 LEU S CB    1 
ATOM   7624 C CG    . LEU E 5 155 ? 155.264 90.417  115.920 1.00 24.17  ? 117 LEU S CG    1 
ATOM   7625 C CD1   . LEU E 5 155 ? 156.692 90.910  116.064 1.00 28.00  ? 117 LEU S CD1   1 
ATOM   7626 C CD2   . LEU E 5 155 ? 154.381 90.945  117.034 1.00 22.91  ? 117 LEU S CD2   1 
ATOM   7627 N N     . THR E 5 156 ? 156.145 87.816  113.534 1.00 29.23  ? 118 THR S N     1 
ATOM   7628 C CA    . THR E 5 156 ? 156.044 86.364  113.581 1.00 30.95  ? 118 THR S CA    1 
ATOM   7629 C C     . THR E 5 156 ? 156.555 85.879  114.929 1.00 35.32  ? 118 THR S C     1 
ATOM   7630 O O     . THR E 5 156 ? 157.695 86.173  115.308 1.00 36.42  ? 118 THR S O     1 
ATOM   7631 C CB    . THR E 5 156 ? 156.832 85.719  112.441 1.00 33.95  ? 118 THR S CB    1 
ATOM   7632 O OG1   . THR E 5 156 ? 158.195 86.153  112.500 1.00 34.25  ? 118 THR S OG1   1 
ATOM   7633 C CG2   . THR E 5 156 ? 156.240 86.112  111.096 1.00 31.60  ? 118 THR S CG2   1 
ATOM   7634 N N     . VAL E 5 157 ? 155.717 85.129  115.640 1.00 37.91  ? 119 VAL S N     1 
ATOM   7635 C CA    . VAL E 5 157 ? 156.048 84.580  116.948 1.00 32.25  ? 119 VAL S CA    1 
ATOM   7636 C C     . VAL E 5 157 ? 156.169 83.070  116.814 1.00 36.24  ? 119 VAL S C     1 
ATOM   7637 O O     . VAL E 5 157 ? 155.241 82.406  116.339 1.00 36.15  ? 119 VAL S O     1 
ATOM   7638 C CB    . VAL E 5 157 ? 154.992 84.958  118.001 1.00 34.54  ? 119 VAL S CB    1 
ATOM   7639 C CG1   . VAL E 5 157 ? 155.393 84.428  119.367 1.00 37.78  ? 119 VAL S CG1   1 
ATOM   7640 C CG2   . VAL E 5 157 ? 154.801 86.466  118.042 1.00 32.33  ? 119 VAL S CG2   1 
ATOM   7641 N N     . SER E 5 158 ? 157.311 82.532  117.229 1.00 40.87  ? 120 SER S N     1 
ATOM   7642 C CA    . SER E 5 158 ? 157.557 81.097  117.142 1.00 44.09  ? 120 SER S CA    1 
ATOM   7643 C C     . SER E 5 158 ? 156.697 80.332  118.143 1.00 45.93  ? 120 SER S C     1 
ATOM   7644 O O     . SER E 5 158 ? 157.119 79.312  118.687 1.00 47.52  ? 120 SER S O     1 
ATOM   7645 C CB    . SER E 5 158 ? 159.037 80.793  117.378 1.00 42.54  ? 120 SER S CB    1 
ATOM   7646 O OG    . SER E 5 158 ? 159.855 81.494  116.458 1.00 40.44  ? 120 SER S OG    1 
ATOM   7647 N N     . GLY E 5 173 ? 132.823 88.723  123.471 1.00 23.56  ? 135 GLY S N     1 
ATOM   7648 C CA    . GLY E 5 173 ? 131.549 88.068  123.703 1.00 24.49  ? 135 GLY S CA    1 
ATOM   7649 C C     . GLY E 5 173 ? 130.359 88.988  123.519 1.00 30.17  ? 135 GLY S C     1 
ATOM   7650 O O     . GLY E 5 173 ? 129.461 88.706  122.725 1.00 21.94  ? 135 GLY S O     1 
ATOM   7651 N N     . SER E 5 174 ? 130.352 90.097  124.259 1.00 31.34  ? 136 SER S N     1 
ATOM   7652 C CA    . SER E 5 174 ? 129.269 91.068  124.170 1.00 29.70  ? 136 SER S CA    1 
ATOM   7653 C C     . SER E 5 174 ? 129.457 92.070  123.039 1.00 28.40  ? 136 SER S C     1 
ATOM   7654 O O     . SER E 5 174 ? 128.537 92.846  122.764 1.00 31.92  ? 136 SER S O     1 
ATOM   7655 C CB    . SER E 5 174 ? 129.126 91.817  125.497 1.00 28.80  ? 136 SER S CB    1 
ATOM   7656 O OG    . SER E 5 174 ? 130.302 92.547  125.800 1.00 30.24  ? 136 SER S OG    1 
ATOM   7657 N N     . ASP E 5 175 ? 130.615 92.075  122.385 1.00 20.48  ? 137 ASP S N     1 
ATOM   7658 C CA    . ASP E 5 175 ? 130.859 93.008  121.299 1.00 21.52  ? 137 ASP S CA    1 
ATOM   7659 C C     . ASP E 5 175 ? 130.071 92.609  120.052 1.00 19.48  ? 137 ASP S C     1 
ATOM   7660 O O     . ASP E 5 175 ? 129.690 91.451  119.864 1.00 14.37  ? 137 ASP S O     1 
ATOM   7661 C CB    . ASP E 5 175 ? 132.355 93.089  120.987 1.00 28.68  ? 137 ASP S CB    1 
ATOM   7662 C CG    . ASP E 5 175 ? 132.962 91.736  120.659 1.00 32.86  ? 137 ASP S CG    1 
ATOM   7663 O OD1   . ASP E 5 175 ? 132.248 90.715  120.744 1.00 33.81  ? 137 ASP S OD1   1 
ATOM   7664 O OD2   . ASP E 5 175 ? 134.163 91.693  120.319 1.00 26.15  ? 137 ASP S OD2   1 
ATOM   7665 N N     . ILE E 5 176 ? 129.823 93.600  119.194 1.00 22.62  ? 138 ILE S N     1 
ATOM   7666 C CA    . ILE E 5 176 ? 129.092 93.360  117.957 1.00 13.74  ? 138 ILE S CA    1 
ATOM   7667 C C     . ILE E 5 176 ? 129.934 92.496  117.031 1.00 15.99  ? 138 ILE S C     1 
ATOM   7668 O O     . ILE E 5 176 ? 131.118 92.774  116.802 1.00 24.44  ? 138 ILE S O     1 
ATOM   7669 C CB    . ILE E 5 176 ? 128.716 94.688  117.283 1.00 10.90  ? 138 ILE S CB    1 
ATOM   7670 C CG1   . ILE E 5 176 ? 127.736 95.476  118.152 1.00 20.16  ? 138 ILE S CG1   1 
ATOM   7671 C CG2   . ILE E 5 176 ? 128.128 94.443  115.903 1.00 16.61  ? 138 ILE S CG2   1 
ATOM   7672 C CD1   . ILE E 5 176 ? 127.412 96.846  117.604 1.00 18.07  ? 138 ILE S CD1   1 
ATOM   7673 N N     . VAL E 5 177 ? 129.328 91.442  116.493 1.00 18.08  ? 139 VAL S N     1 
ATOM   7674 C CA    . VAL E 5 177 ? 129.987 90.558  115.539 1.00 21.34  ? 139 VAL S CA    1 
ATOM   7675 C C     . VAL E 5 177 ? 129.473 90.881  114.143 1.00 20.56  ? 139 VAL S C     1 
ATOM   7676 O O     . VAL E 5 177 ? 128.260 90.989  113.924 1.00 19.68  ? 139 VAL S O     1 
ATOM   7677 C CB    . VAL E 5 177 ? 129.762 89.077  115.897 1.00 21.39  ? 139 VAL S CB    1 
ATOM   7678 C CG1   . VAL E 5 177 ? 128.281 88.765  116.040 1.00 14.88  ? 139 VAL S CG1   1 
ATOM   7679 C CG2   . VAL E 5 177 ? 130.401 88.174  114.852 1.00 16.11  ? 139 VAL S CG2   1 
ATOM   7680 N N     . MET E 5 178 ? 130.397 91.065  113.206 1.00 22.96  ? 140 MET S N     1 
ATOM   7681 C CA    . MET E 5 178 ? 130.075 91.347  111.815 1.00 19.53  ? 140 MET S CA    1 
ATOM   7682 C C     . MET E 5 178 ? 130.313 90.088  110.996 1.00 15.53  ? 140 MET S C     1 
ATOM   7683 O O     . MET E 5 178 ? 131.401 89.505  111.052 1.00 24.95  ? 140 MET S O     1 
ATOM   7684 C CB    . MET E 5 178 ? 130.928 92.498  111.276 1.00 14.61  ? 140 MET S CB    1 
ATOM   7685 C CG    . MET E 5 178 ? 130.791 93.800  112.049 1.00 5.73   ? 140 MET S CG    1 
ATOM   7686 S SD    . MET E 5 178 ? 129.138 94.504  111.951 1.00 34.17  ? 140 MET S SD    1 
ATOM   7687 C CE    . MET E 5 178 ? 128.985 94.757  110.186 1.00 15.13  ? 140 MET S CE    1 
ATOM   7688 N N     . THR E 5 179 ? 129.303 89.669  110.241 1.00 8.35   ? 141 THR S N     1 
ATOM   7689 C CA    . THR E 5 179 ? 129.393 88.461  109.436 1.00 20.93  ? 141 THR S CA    1 
ATOM   7690 C C     . THR E 5 179 ? 129.185 88.797  107.966 1.00 23.93  ? 141 THR S C     1 
ATOM   7691 O O     . THR E 5 179 ? 128.460 89.733  107.621 1.00 19.72  ? 141 THR S O     1 
ATOM   7692 C CB    . THR E 5 179 ? 128.369 87.408  109.887 1.00 19.93  ? 141 THR S CB    1 
ATOM   7693 O OG1   . THR E 5 179 ? 128.561 86.200  109.139 1.00 18.44  ? 141 THR S OG1   1 
ATOM   7694 C CG2   . THR E 5 179 ? 126.949 87.909  109.687 1.00 19.09  ? 141 THR S CG2   1 
ATOM   7695 N N     . GLN E 5 180 ? 129.855 88.039  107.103 1.00 25.09  ? 142 GLN S N     1 
ATOM   7696 C CA    . GLN E 5 180 ? 129.737 88.193  105.661 1.00 21.71  ? 142 GLN S CA    1 
ATOM   7697 C C     . GLN E 5 180 ? 129.262 86.876  105.066 1.00 29.52  ? 142 GLN S C     1 
ATOM   7698 O O     . GLN E 5 180 ? 129.846 85.822  105.336 1.00 21.58  ? 142 GLN S O     1 
ATOM   7699 C CB    . GLN E 5 180 ? 131.071 88.625  105.045 1.00 15.20  ? 142 GLN S CB    1 
ATOM   7700 C CG    . GLN E 5 180 ? 131.606 89.928  105.621 1.00 18.80  ? 142 GLN S CG    1 
ATOM   7701 C CD    . GLN E 5 180 ? 132.373 90.752  104.608 1.00 22.62  ? 142 GLN S CD    1 
ATOM   7702 O OE1   . GLN E 5 180 ? 131.971 90.865  103.450 1.00 28.26  ? 142 GLN S OE1   1 
ATOM   7703 N NE2   . GLN E 5 180 ? 133.481 91.340  105.041 1.00 17.29  ? 142 GLN S NE2   1 
ATOM   7704 N N     . ALA E 5 181 ? 128.196 86.943  104.264 1.00 40.61  ? 143 ALA S N     1 
ATOM   7705 C CA    . ALA E 5 181 ? 127.569 85.727  103.755 1.00 37.91  ? 143 ALA S CA    1 
ATOM   7706 C C     . ALA E 5 181 ? 128.510 84.945  102.847 1.00 38.74  ? 143 ALA S C     1 
ATOM   7707 O O     . ALA E 5 181 ? 128.576 83.713  102.923 1.00 36.46  ? 143 ALA S O     1 
ATOM   7708 C CB    . ALA E 5 181 ? 126.277 86.075  103.015 1.00 34.27  ? 143 ALA S CB    1 
ATOM   7709 N N     . THR E 5 182 ? 129.245 85.639  101.983 1.00 37.17  ? 144 THR S N     1 
ATOM   7710 C CA    . THR E 5 182 ? 130.113 85.002  101.004 1.00 35.71  ? 144 THR S CA    1 
ATOM   7711 C C     . THR E 5 182 ? 131.568 85.327  101.306 1.00 36.47  ? 144 THR S C     1 
ATOM   7712 O O     . THR E 5 182 ? 131.904 86.466  101.646 1.00 40.69  ? 144 THR S O     1 
ATOM   7713 C CB    . THR E 5 182 ? 129.768 85.451  99.580  1.00 35.12  ? 144 THR S CB    1 
ATOM   7714 N N     . SER E 5 183 ? 132.428 84.318  101.182 1.00 38.68  ? 145 SER S N     1 
ATOM   7715 C CA    . SER E 5 183 ? 133.862 84.492  101.371 1.00 39.28  ? 145 SER S CA    1 
ATOM   7716 C C     . SER E 5 183 ? 134.614 84.706  100.067 1.00 39.56  ? 145 SER S C     1 
ATOM   7717 O O     . SER E 5 183 ? 135.532 85.531  100.023 1.00 39.60  ? 145 SER S O     1 
ATOM   7718 C CB    . SER E 5 183 ? 134.453 83.278  102.096 1.00 38.04  ? 145 SER S CB    1 
ATOM   7719 O OG    . SER E 5 183 ? 134.215 82.085  101.369 1.00 40.59  ? 145 SER S OG    1 
ATOM   7720 N N     . SER E 5 184 ? 134.247 83.988  99.007  1.00 42.53  ? 146 SER S N     1 
ATOM   7721 C CA    . SER E 5 184 ? 134.862 84.154  97.698  1.00 44.64  ? 146 SER S CA    1 
ATOM   7722 C C     . SER E 5 184 ? 133.766 84.277  96.653  1.00 43.60  ? 146 SER S C     1 
ATOM   7723 O O     . SER E 5 184 ? 132.865 83.435  96.595  1.00 43.66  ? 146 SER S O     1 
ATOM   7724 C CB    . SER E 5 184 ? 135.787 82.978  97.362  1.00 40.64  ? 146 SER S CB    1 
ATOM   7725 O OG    . SER E 5 184 ? 136.292 83.089  96.043  1.00 40.49  ? 146 SER S OG    1 
ATOM   7726 N N     . VAL E 5 185 ? 133.844 85.322  95.835  1.00 43.54  ? 147 VAL S N     1 
ATOM   7727 C CA    . VAL E 5 185 ? 132.852 85.562  94.790  1.00 46.80  ? 147 VAL S CA    1 
ATOM   7728 C C     . VAL E 5 185 ? 133.554 85.645  93.440  1.00 48.78  ? 147 VAL S C     1 
ATOM   7729 O O     . VAL E 5 185 ? 134.286 86.612  93.182  1.00 44.24  ? 147 VAL S O     1 
ATOM   7730 C CB    . VAL E 5 185 ? 132.044 86.839  95.068  1.00 47.03  ? 147 VAL S CB    1 
ATOM   7731 C CG1   . VAL E 5 185 ? 130.958 87.017  94.018  1.00 44.36  ? 147 VAL S CG1   1 
ATOM   7732 C CG2   . VAL E 5 185 ? 131.436 86.793  96.461  1.00 48.44  ? 147 VAL S CG2   1 
ATOM   7733 N N     . PRO E 5 186 ? 133.369 84.666  92.554  1.00 54.28  ? 148 PRO S N     1 
ATOM   7734 C CA    . PRO E 5 186 ? 133.953 84.761  91.207  1.00 51.04  ? 148 PRO S CA    1 
ATOM   7735 C C     . PRO E 5 186 ? 133.200 85.792  90.379  1.00 50.09  ? 148 PRO S C     1 
ATOM   7736 O O     . PRO E 5 186 ? 131.988 85.681  90.181  1.00 48.79  ? 148 PRO S O     1 
ATOM   7737 C CB    . PRO E 5 186 ? 133.789 83.344  90.639  1.00 50.97  ? 148 PRO S CB    1 
ATOM   7738 C CG    . PRO E 5 186 ? 133.277 82.491  91.778  1.00 49.27  ? 148 PRO S CG    1 
ATOM   7739 C CD    . PRO E 5 186 ? 132.623 83.414  92.748  1.00 47.20  ? 148 PRO S CD    1 
ATOM   7740 N N     . VAL E 5 187 ? 133.925 86.802  89.897  1.00 52.74  ? 149 VAL S N     1 
ATOM   7741 C CA    . VAL E 5 187 ? 133.326 87.921  89.184  1.00 51.41  ? 149 VAL S CA    1 
ATOM   7742 C C     . VAL E 5 187 ? 134.048 88.119  87.859  1.00 52.11  ? 149 VAL S C     1 
ATOM   7743 O O     . VAL E 5 187 ? 135.173 87.657  87.656  1.00 51.62  ? 149 VAL S O     1 
ATOM   7744 C CB    . VAL E 5 187 ? 133.358 89.227  90.009  1.00 51.30  ? 149 VAL S CB    1 
ATOM   7745 C CG1   . VAL E 5 187 ? 132.743 89.007  91.384  1.00 50.92  ? 149 VAL S CG1   1 
ATOM   7746 C CG2   . VAL E 5 187 ? 134.783 89.745  90.132  1.00 49.34  ? 149 VAL S CG2   1 
ATOM   7747 N N     . THR E 5 188 ? 133.372 88.818  86.948  1.00 53.21  ? 150 THR S N     1 
ATOM   7748 C CA    . THR E 5 188 ? 133.880 89.156  85.632  1.00 55.76  ? 150 THR S CA    1 
ATOM   7749 C C     . THR E 5 188 ? 133.851 90.668  85.441  1.00 54.80  ? 150 THR S C     1 
ATOM   7750 O O     . THR E 5 188 ? 132.867 91.316  85.815  1.00 55.39  ? 150 THR S O     1 
ATOM   7751 C CB    . THR E 5 188 ? 133.044 88.477  84.531  1.00 54.33  ? 150 THR S CB    1 
ATOM   7752 O OG1   . THR E 5 188 ? 133.087 87.055  84.705  1.00 52.49  ? 150 THR S OG1   1 
ATOM   7753 C CG2   . THR E 5 188 ? 133.568 88.827  83.146  1.00 54.07  ? 150 THR S CG2   1 
ATOM   7754 N N     . PRO E 5 189 ? 134.911 91.259  84.887  1.00 55.40  ? 151 PRO S N     1 
ATOM   7755 C CA    . PRO E 5 189 ? 134.926 92.716  84.700  1.00 54.75  ? 151 PRO S CA    1 
ATOM   7756 C C     . PRO E 5 189 ? 133.764 93.187  83.838  1.00 55.36  ? 151 PRO S C     1 
ATOM   7757 O O     . PRO E 5 189 ? 133.379 92.534  82.866  1.00 56.65  ? 151 PRO S O     1 
ATOM   7758 C CB    . PRO E 5 189 ? 136.273 92.970  84.016  1.00 55.92  ? 151 PRO S CB    1 
ATOM   7759 C CG    . PRO E 5 189 ? 137.130 91.832  84.443  1.00 55.94  ? 151 PRO S CG    1 
ATOM   7760 C CD    . PRO E 5 189 ? 136.216 90.647  84.581  1.00 54.94  ? 151 PRO S CD    1 
ATOM   7761 N N     . GLY E 5 190 ? 133.207 94.340  84.207  1.00 56.40  ? 152 GLY S N     1 
ATOM   7762 C CA    . GLY E 5 190 ? 132.069 94.913  83.523  1.00 52.86  ? 152 GLY S CA    1 
ATOM   7763 C C     . GLY E 5 190 ? 130.726 94.610  84.152  1.00 53.38  ? 152 GLY S C     1 
ATOM   7764 O O     . GLY E 5 190 ? 129.720 95.195  83.731  1.00 54.87  ? 152 GLY S O     1 
ATOM   7765 N N     . GLU E 5 191 ? 130.677 93.723  85.142  1.00 53.74  ? 153 GLU S N     1 
ATOM   7766 C CA    . GLU E 5 191 ? 129.427 93.358  85.788  1.00 52.90  ? 153 GLU S CA    1 
ATOM   7767 C C     . GLU E 5 191 ? 129.218 94.184  87.056  1.00 53.16  ? 153 GLU S C     1 
ATOM   7768 O O     . GLU E 5 191 ? 130.029 95.039  87.419  1.00 53.31  ? 153 GLU S O     1 
ATOM   7769 C CB    . GLU E 5 191 ? 129.408 91.864  86.107  1.00 50.66  ? 153 GLU S CB    1 
ATOM   7770 C CG    . GLU E 5 191 ? 129.547 90.961  84.895  1.00 53.77  ? 153 GLU S CG    1 
ATOM   7771 C CD    . GLU E 5 191 ? 129.811 89.518  85.278  1.00 54.47  ? 153 GLU S CD    1 
ATOM   7772 O OE1   . GLU E 5 191 ? 130.339 89.283  86.385  1.00 52.38  ? 153 GLU S OE1   1 
ATOM   7773 O OE2   . GLU E 5 191 ? 129.491 88.619  84.472  1.00 54.66  ? 153 GLU S OE2   1 
ATOM   7774 N N     . SER E 5 192 ? 128.107 93.923  87.739  1.00 46.61  ? 154 SER S N     1 
ATOM   7775 C CA    . SER E 5 192 ? 127.784 94.556  89.010  1.00 43.77  ? 154 SER S CA    1 
ATOM   7776 C C     . SER E 5 192 ? 127.827 93.504  90.109  1.00 44.47  ? 154 SER S C     1 
ATOM   7777 O O     . SER E 5 192 ? 127.180 92.457  89.997  1.00 44.97  ? 154 SER S O     1 
ATOM   7778 C CB    . SER E 5 192 ? 126.406 95.219  88.961  1.00 45.95  ? 154 SER S CB    1 
ATOM   7779 N N     . VAL E 5 193 ? 128.585 93.784  91.165  1.00 40.57  ? 155 VAL S N     1 
ATOM   7780 C CA    . VAL E 5 193 ? 128.810 92.839  92.253  1.00 38.89  ? 155 VAL S CA    1 
ATOM   7781 C C     . VAL E 5 193 ? 128.249 93.433  93.535  1.00 38.52  ? 155 VAL S C     1 
ATOM   7782 O O     . VAL E 5 193 ? 128.527 94.592  93.861  1.00 40.24  ? 155 VAL S O     1 
ATOM   7783 C CB    . VAL E 5 193 ? 130.304 92.506  92.414  1.00 37.47  ? 155 VAL S CB    1 
ATOM   7784 C CG1   . VAL E 5 193 ? 130.493 91.392  93.432  1.00 37.49  ? 155 VAL S CG1   1 
ATOM   7785 C CG2   . VAL E 5 193 ? 130.906 92.121  91.073  1.00 39.82  ? 155 VAL S CG2   1 
ATOM   7786 N N     . SER E 5 194 ? 127.461 92.642  94.258  1.00 29.93  ? 156 SER S N     1 
ATOM   7787 C CA    . SER E 5 194 ? 126.857 93.061  95.517  1.00 29.85  ? 156 SER S CA    1 
ATOM   7788 C C     . SER E 5 194 ? 127.454 92.227  96.644  1.00 30.64  ? 156 SER S C     1 
ATOM   7789 O O     . SER E 5 194 ? 127.246 91.010  96.702  1.00 37.58  ? 156 SER S O     1 
ATOM   7790 C CB    . SER E 5 194 ? 125.338 92.914  95.469  1.00 33.38  ? 156 SER S CB    1 
ATOM   7791 O OG    . SER E 5 194 ? 124.756 93.225  96.722  1.00 39.23  ? 156 SER S OG    1 
ATOM   7792 N N     . ILE E 5 195 ? 128.196 92.879  97.530  1.00 19.44  ? 157 ILE S N     1 
ATOM   7793 C CA    . ILE E 5 195 ? 128.759 92.236  98.712  1.00 24.95  ? 157 ILE S CA    1 
ATOM   7794 C C     . ILE E 5 195 ? 127.866 92.548  99.902  1.00 19.97  ? 157 ILE S C     1 
ATOM   7795 O O     . ILE E 5 195 ? 127.601 93.716  100.204 1.00 22.34  ? 157 ILE S O     1 
ATOM   7796 C CB    . ILE E 5 195 ? 130.206 92.703  98.964  1.00 27.48  ? 157 ILE S CB    1 
ATOM   7797 C CG1   . ILE E 5 195 ? 131.119 92.312  97.798  1.00 23.23  ? 157 ILE S CG1   1 
ATOM   7798 C CG2   . ILE E 5 195 ? 130.730 92.132  100.269 1.00 26.43  ? 157 ILE S CG2   1 
ATOM   7799 C CD1   . ILE E 5 195 ? 131.273 93.388  96.743  1.00 28.99  ? 157 ILE S CD1   1 
ATOM   7800 N N     . SER E 5 196 ? 127.406 91.509  100.590 1.00 15.41  ? 158 SER S N     1 
ATOM   7801 C CA    . SER E 5 196 ? 126.446 91.659  101.672 1.00 22.79  ? 158 SER S CA    1 
ATOM   7802 C C     . SER E 5 196 ? 127.100 91.349  103.011 1.00 21.29  ? 158 SER S C     1 
ATOM   7803 O O     . SER E 5 196 ? 128.045 90.559  103.093 1.00 25.11  ? 158 SER S O     1 
ATOM   7804 C CB    . SER E 5 196 ? 125.231 90.745  101.467 1.00 25.01  ? 158 SER S CB    1 
ATOM   7805 O OG    . SER E 5 196 ? 124.269 90.939  102.490 1.00 20.53  ? 158 SER S OG    1 
ATOM   7806 N N     . CYS E 5 197 ? 126.588 91.988  104.061 1.00 19.19  ? 159 CYS S N     1 
ATOM   7807 C CA    . CYS E 5 197 ? 127.067 91.744  105.412 1.00 17.70  ? 159 CYS S CA    1 
ATOM   7808 C C     . CYS E 5 197 ? 125.921 91.945  106.392 1.00 20.05  ? 159 CYS S C     1 
ATOM   7809 O O     . CYS E 5 197 ? 124.925 92.609  106.091 1.00 21.98  ? 159 CYS S O     1 
ATOM   7810 C CB    . CYS E 5 197 ? 128.242 92.658  105.776 1.00 20.44  ? 159 CYS S CB    1 
ATOM   7811 S SG    . CYS E 5 197 ? 127.813 94.401  105.956 1.00 39.34  ? 159 CYS S SG    1 
ATOM   7812 N N     . ARG E 5 198 ? 126.077 91.357  107.575 1.00 22.59  ? 160 ARG S N     1 
ATOM   7813 C CA    . ARG E 5 198 ? 125.074 91.436  108.625 1.00 18.35  ? 160 ARG S CA    1 
ATOM   7814 C C     . ARG E 5 198 ? 125.762 91.700  109.957 1.00 24.16  ? 160 ARG S C     1 
ATOM   7815 O O     . ARG E 5 198 ? 126.942 91.388  110.147 1.00 29.55  ? 160 ARG S O     1 
ATOM   7816 C CB    . ARG E 5 198 ? 124.231 90.155  108.699 1.00 19.84  ? 160 ARG S CB    1 
ATOM   7817 C CG    . ARG E 5 198 ? 122.853 90.351  109.310 1.00 28.82  ? 160 ARG S CG    1 
ATOM   7818 C CD    . ARG E 5 198 ? 122.160 89.022  109.566 1.00 32.18  ? 160 ARG S CD    1 
ATOM   7819 N NE    . ARG E 5 198 ? 122.742 88.308  110.697 1.00 31.87  ? 160 ARG S NE    1 
ATOM   7820 C CZ    . ARG E 5 198 ? 123.520 87.240  110.588 1.00 32.27  ? 160 ARG S CZ    1 
ATOM   7821 N NH1   . ARG E 5 198 ? 123.826 86.725  109.409 1.00 30.08  ? 160 ARG S NH1   1 
ATOM   7822 N NH2   . ARG E 5 198 ? 124.000 86.673  111.691 1.00 30.47  ? 160 ARG S NH2   1 
ATOM   7823 N N     . SER E 5 199 ? 125.004 92.286  110.880 1.00 19.31  ? 161 SER S N     1 
ATOM   7824 C CA    . SER E 5 199 ? 125.496 92.634  112.202 1.00 17.13  ? 161 SER S CA    1 
ATOM   7825 C C     . SER E 5 199 ? 124.578 92.045  113.262 1.00 23.16  ? 161 SER S C     1 
ATOM   7826 O O     . SER E 5 199 ? 123.372 91.897  113.049 1.00 28.13  ? 161 SER S O     1 
ATOM   7827 C CB    . SER E 5 199 ? 125.589 94.155  112.379 1.00 16.91  ? 161 SER S CB    1 
ATOM   7828 O OG    . SER E 5 199 ? 125.669 94.506  113.748 1.00 19.75  ? 161 SER S OG    1 
ATOM   7829 N N     . SER E 5 200 ? 125.166 91.698  114.410 1.00 17.73  ? 162 SER S N     1 
ATOM   7830 C CA    . SER E 5 200 ? 124.368 91.193  115.523 1.00 18.62  ? 162 SER S CA    1 
ATOM   7831 C C     . SER E 5 200 ? 123.420 92.262  116.051 1.00 19.92  ? 162 SER S C     1 
ATOM   7832 O O     . SER E 5 200 ? 122.261 91.973  116.366 1.00 18.05  ? 162 SER S O     1 
ATOM   7833 C CB    . SER E 5 200 ? 125.281 90.689  116.639 1.00 20.79  ? 162 SER S CB    1 
ATOM   7834 O OG    . SER E 5 200 ? 125.881 91.767  117.335 1.00 21.20  ? 162 SER S OG    1 
ATOM   7835 N N     . LYS E 5 201 ? 123.895 93.500  116.153 1.00 21.04  ? 163 LYS S N     1 
ATOM   7836 C CA    . LYS E 5 201 ? 123.089 94.623  116.602 1.00 18.11  ? 163 LYS S CA    1 
ATOM   7837 C C     . LYS E 5 201 ? 123.006 95.661  115.492 1.00 18.42  ? 163 LYS S C     1 
ATOM   7838 O O     . LYS E 5 201 ? 123.945 95.830  114.709 1.00 24.61  ? 163 LYS S O     1 
ATOM   7839 C CB    . LYS E 5 201 ? 123.673 95.254  117.874 1.00 14.51  ? 163 LYS S CB    1 
ATOM   7840 C CG    . LYS E 5 201 ? 122.811 96.351  118.480 1.00 19.54  ? 163 LYS S CG    1 
ATOM   7841 C CD    . LYS E 5 201 ? 122.984 96.430  119.986 1.00 22.43  ? 163 LYS S CD    1 
ATOM   7842 C CE    . LYS E 5 201 ? 124.395 96.839  120.362 1.00 16.64  ? 163 LYS S CE    1 
ATOM   7843 N NZ    . LYS E 5 201 ? 124.600 96.783  121.835 1.00 15.89  ? 163 LYS S NZ    1 
ATOM   7844 N N     . SER E 5 202 ? 121.865 96.343  115.421 1.00 19.12  ? 164 SER S N     1 
ATOM   7845 C CA    . SER E 5 202 ? 121.675 97.379  114.415 1.00 16.59  ? 164 SER S CA    1 
ATOM   7846 C C     . SER E 5 202 ? 122.707 98.485  114.593 1.00 16.71  ? 164 SER S C     1 
ATOM   7847 O O     . SER E 5 202 ? 122.890 99.008  115.695 1.00 18.28  ? 164 SER S O     1 
ATOM   7848 C CB    . SER E 5 202 ? 120.262 97.952  114.509 1.00 17.81  ? 164 SER S CB    1 
ATOM   7849 O OG    . SER E 5 202 ? 120.048 98.948  113.523 1.00 16.01  ? 164 SER S OG    1 
ATOM   7850 N N     . LEU E 5 203 ? 123.377 98.842  113.499 1.00 18.58  ? 165 LEU S N     1 
ATOM   7851 C CA    . LEU E 5 203 ? 124.419 99.861  113.532 1.00 17.87  ? 165 LEU S CA    1 
ATOM   7852 C C     . LEU E 5 203 ? 123.869 101.277 113.445 1.00 12.35  ? 165 LEU S C     1 
ATOM   7853 O O     . LEU E 5 203 ? 124.645 102.232 113.544 1.00 8.23   ? 165 LEU S O     1 
ATOM   7854 C CB    . LEU E 5 203 ? 125.421 99.622  112.399 1.00 10.52  ? 165 LEU S CB    1 
ATOM   7855 C CG    . LEU E 5 203 ? 126.207 98.312  112.478 1.00 5.29   ? 165 LEU S CG    1 
ATOM   7856 C CD1   . LEU E 5 203 ? 127.308 98.277  111.431 1.00 11.89  ? 165 LEU S CD1   1 
ATOM   7857 C CD2   . LEU E 5 203 ? 126.783 98.117  113.870 1.00 7.84   ? 165 LEU S CD2   1 
ATOM   7858 N N     . LEU E 5 204 ? 122.561 101.436 113.258 1.00 18.10  ? 166 LEU S N     1 
ATOM   7859 C CA    . LEU E 5 204 ? 121.948 102.755 113.238 1.00 17.09  ? 166 LEU S CA    1 
ATOM   7860 C C     . LEU E 5 204 ? 121.850 103.299 114.658 1.00 15.22  ? 166 LEU S C     1 
ATOM   7861 O O     . LEU E 5 204 ? 121.397 102.600 115.571 1.00 22.05  ? 166 LEU S O     1 
ATOM   7862 C CB    . LEU E 5 204 ? 120.566 102.688 112.589 1.00 11.50  ? 166 LEU S CB    1 
ATOM   7863 C CG    . LEU E 5 204 ? 119.882 104.008 112.229 1.00 13.37  ? 166 LEU S CG    1 
ATOM   7864 C CD1   . LEU E 5 204 ? 119.182 103.887 110.887 1.00 13.12  ? 166 LEU S CD1   1 
ATOM   7865 C CD2   . LEU E 5 204 ? 118.890 104.412 113.305 1.00 19.90  ? 166 LEU S CD2   1 
ATOM   7866 N N     . HIS E 5 205 ? 122.277 104.542 114.843 1.00 11.74  ? 167 HIS S N     1 
ATOM   7867 C CA    . HIS E 5 205 ? 122.271 105.190 116.145 1.00 13.23  ? 167 HIS S CA    1 
ATOM   7868 C C     . HIS E 5 205 ? 121.104 106.167 116.251 1.00 20.46  ? 167 HIS S C     1 
ATOM   7869 O O     . HIS E 5 205 ? 120.421 106.475 115.272 1.00 11.00  ? 167 HIS S O     1 
ATOM   7870 C CB    . HIS E 5 205 ? 123.601 105.910 116.391 1.00 4.24   ? 167 HIS S CB    1 
ATOM   7871 C CG    . HIS E 5 205 ? 123.862 106.227 117.831 1.00 13.38  ? 167 HIS S CG    1 
ATOM   7872 N ND1   . HIS E 5 205 ? 123.687 107.487 118.359 1.00 15.78  ? 167 HIS S ND1   1 
ATOM   7873 C CD2   . HIS E 5 205 ? 124.281 105.446 118.855 1.00 15.23  ? 167 HIS S CD2   1 
ATOM   7874 C CE1   . HIS E 5 205 ? 123.988 107.470 119.645 1.00 17.86  ? 167 HIS S CE1   1 
ATOM   7875 N NE2   . HIS E 5 205 ? 124.352 106.243 119.971 1.00 15.34  ? 167 HIS S NE2   1 
ATOM   7876 N N     . SER E 5 206 ? 120.882 106.656 117.474 1.00 24.75  ? 168 SER S N     1 
ATOM   7877 C CA    . SER E 5 206 ? 119.802 107.604 117.721 1.00 19.87  ? 168 SER S CA    1 
ATOM   7878 C C     . SER E 5 206 ? 119.996 108.915 116.971 1.00 19.77  ? 168 SER S C     1 
ATOM   7879 O O     . SER E 5 206 ? 119.021 109.646 116.763 1.00 20.93  ? 168 SER S O     1 
ATOM   7880 C CB    . SER E 5 206 ? 119.679 107.876 119.220 1.00 20.37  ? 168 SER S CB    1 
ATOM   7881 O OG    . SER E 5 206 ? 119.756 106.673 119.964 1.00 25.09  ? 168 SER S OG    1 
ATOM   7882 N N     . ASN E 5 207 ? 121.223 109.231 116.562 1.00 13.56  ? 169 ASN S N     1 
ATOM   7883 C CA    . ASN E 5 207 ? 121.503 110.451 115.820 1.00 12.96  ? 169 ASN S CA    1 
ATOM   7884 C C     . ASN E 5 207 ? 121.285 110.296 114.320 1.00 12.62  ? 169 ASN S C     1 
ATOM   7885 O O     . ASN E 5 207 ? 121.507 111.255 113.574 1.00 20.81  ? 169 ASN S O     1 
ATOM   7886 C CB    . ASN E 5 207 ? 122.939 110.920 116.091 1.00 12.73  ? 169 ASN S CB    1 
ATOM   7887 C CG    . ASN E 5 207 ? 123.966 109.821 115.888 1.00 10.76  ? 169 ASN S CG    1 
ATOM   7888 O OD1   . ASN E 5 207 ? 123.755 108.888 115.115 1.00 13.44  ? 169 ASN S OD1   1 
ATOM   7889 N ND2   . ASN E 5 207 ? 125.089 109.928 116.587 1.00 11.95  ? 169 ASN S ND2   1 
ATOM   7890 N N     . GLY E 5 208 ? 120.860 109.119 113.863 1.00 2.52   ? 170 GLY S N     1 
ATOM   7891 C CA    . GLY E 5 208 ? 120.622 108.876 112.459 1.00 9.38   ? 170 GLY S CA    1 
ATOM   7892 C C     . GLY E 5 208 ? 121.804 108.330 111.690 1.00 11.65  ? 170 GLY S C     1 
ATOM   7893 O O     . GLY E 5 208 ? 121.655 108.010 110.504 1.00 19.31  ? 170 GLY S O     1 
ATOM   7894 N N     . ASN E 5 209 ? 122.969 108.212 112.320 1.00 5.61   ? 171 ASN S N     1 
ATOM   7895 C CA    . ASN E 5 209 ? 124.155 107.687 111.660 1.00 2.77   ? 171 ASN S CA    1 
ATOM   7896 C C     . ASN E 5 209 ? 124.212 106.172 111.801 1.00 9.38   ? 171 ASN S C     1 
ATOM   7897 O O     . ASN E 5 209 ? 123.993 105.627 112.886 1.00 16.95  ? 171 ASN S O     1 
ATOM   7898 C CB    . ASN E 5 209 ? 125.421 108.311 112.249 1.00 5.11   ? 171 ASN S CB    1 
ATOM   7899 C CG    . ASN E 5 209 ? 125.803 109.608 111.568 1.00 17.75  ? 171 ASN S CG    1 
ATOM   7900 O OD1   . ASN E 5 209 ? 125.550 109.796 110.378 1.00 17.65  ? 171 ASN S OD1   1 
ATOM   7901 N ND2   . ASN E 5 209 ? 126.419 110.511 112.320 1.00 15.76  ? 171 ASN S ND2   1 
ATOM   7902 N N     . THR E 5 210 ? 124.503 105.497 110.693 1.00 6.99   ? 172 THR S N     1 
ATOM   7903 C CA    . THR E 5 210 ? 124.702 104.050 110.670 1.00 5.32   ? 172 THR S CA    1 
ATOM   7904 C C     . THR E 5 210 ? 126.195 103.809 110.484 1.00 10.17  ? 172 THR S C     1 
ATOM   7905 O O     . THR E 5 210 ? 126.727 103.975 109.384 1.00 13.19  ? 172 THR S O     1 
ATOM   7906 C CB    . THR E 5 210 ? 123.884 103.395 109.562 1.00 8.98   ? 172 THR S CB    1 
ATOM   7907 O OG1   . THR E 5 210 ? 122.555 103.928 109.568 1.00 16.97  ? 172 THR S OG1   1 
ATOM   7908 C CG2   . THR E 5 210 ? 123.817 101.893 109.778 1.00 9.86   ? 172 THR S CG2   1 
ATOM   7909 N N     . TYR E 5 211 ? 126.867 103.408 111.562 1.00 16.23  ? 173 TYR S N     1 
ATOM   7910 C CA    . TYR E 5 211 ? 128.327 103.333 111.588 1.00 4.23   ? 173 TYR S CA    1 
ATOM   7911 C C     . TYR E 5 211 ? 128.786 102.015 110.971 1.00 5.22   ? 173 TYR S C     1 
ATOM   7912 O O     . TYR E 5 211 ? 129.092 101.035 111.654 1.00 1.11   ? 173 TYR S O     1 
ATOM   7913 C CB    . TYR E 5 211 ? 128.838 103.500 113.011 1.00 0.00   ? 173 TYR S CB    1 
ATOM   7914 C CG    . TYR E 5 211 ? 128.411 104.803 113.643 1.00 3.99   ? 173 TYR S CG    1 
ATOM   7915 C CD1   . TYR E 5 211 ? 129.084 105.983 113.364 1.00 10.68  ? 173 TYR S CD1   1 
ATOM   7916 C CD2   . TYR E 5 211 ? 127.327 104.855 114.507 1.00 8.35   ? 173 TYR S CD2   1 
ATOM   7917 C CE1   . TYR E 5 211 ? 128.695 107.178 113.934 1.00 8.96   ? 173 TYR S CE1   1 
ATOM   7918 C CE2   . TYR E 5 211 ? 126.931 106.045 115.081 1.00 13.34  ? 173 TYR S CE2   1 
ATOM   7919 C CZ    . TYR E 5 211 ? 127.619 107.203 114.792 1.00 10.21  ? 173 TYR S CZ    1 
ATOM   7920 O OH    . TYR E 5 211 ? 127.229 108.393 115.362 1.00 13.57  ? 173 TYR S OH    1 
ATOM   7921 N N     . LEU E 5 212 ? 128.836 102.003 109.641 1.00 7.62   ? 174 LEU S N     1 
ATOM   7922 C CA    . LEU E 5 212 ? 129.389 100.893 108.879 1.00 9.55   ? 174 LEU S CA    1 
ATOM   7923 C C     . LEU E 5 212 ? 130.474 101.415 107.952 1.00 5.65   ? 174 LEU S C     1 
ATOM   7924 O O     . LEU E 5 212 ? 130.321 102.476 107.340 1.00 4.10   ? 174 LEU S O     1 
ATOM   7925 C CB    . LEU E 5 212 ? 128.327 100.180 108.046 1.00 1.80   ? 174 LEU S CB    1 
ATOM   7926 C CG    . LEU E 5 212 ? 128.915 98.989  107.287 1.00 2.15   ? 174 LEU S CG    1 
ATOM   7927 C CD1   . LEU E 5 212 ? 129.344 97.883  108.244 1.00 6.79   ? 174 LEU S CD1   1 
ATOM   7928 C CD2   . LEU E 5 212 ? 127.983 98.479  106.227 1.00 7.01   ? 174 LEU S CD2   1 
ATOM   7929 N N     . TYR E 5 213 ? 131.568 100.665 107.845 1.00 5.42   ? 175 TYR S N     1 
ATOM   7930 C CA    . TYR E 5 213 ? 132.694 101.042 107.007 1.00 0.00   ? 175 TYR S CA    1 
ATOM   7931 C C     . TYR E 5 213 ? 133.031 99.892  106.072 1.00 4.95   ? 175 TYR S C     1 
ATOM   7932 O O     . TYR E 5 213 ? 133.183 98.750  106.514 1.00 14.44  ? 175 TYR S O     1 
ATOM   7933 C CB    . TYR E 5 213 ? 133.911 101.421 107.859 1.00 0.32   ? 175 TYR S CB    1 
ATOM   7934 C CG    . TYR E 5 213 ? 133.720 102.708 108.626 1.00 0.73   ? 175 TYR S CG    1 
ATOM   7935 C CD1   . TYR E 5 213 ? 132.844 102.774 109.700 1.00 2.13   ? 175 TYR S CD1   1 
ATOM   7936 C CD2   . TYR E 5 213 ? 134.405 103.860 108.270 1.00 0.00   ? 175 TYR S CD2   1 
ATOM   7937 C CE1   . TYR E 5 213 ? 132.656 103.943 110.395 1.00 0.00   ? 175 TYR S CE1   1 
ATOM   7938 C CE2   . TYR E 5 213 ? 134.226 105.034 108.966 1.00 0.00   ? 175 TYR S CE2   1 
ATOM   7939 C CZ    . TYR E 5 213 ? 133.349 105.069 110.025 1.00 5.66   ? 175 TYR S CZ    1 
ATOM   7940 O OH    . TYR E 5 213 ? 133.161 106.235 110.722 1.00 16.58  ? 175 TYR S OH    1 
ATOM   7941 N N     . TRP E 5 214 ? 133.137 100.199 104.786 1.00 5.55   ? 176 TRP S N     1 
ATOM   7942 C CA    . TRP E 5 214 ? 133.523 99.243  103.758 1.00 0.00   ? 176 TRP S CA    1 
ATOM   7943 C C     . TRP E 5 214 ? 134.945 99.558  103.323 1.00 0.12   ? 176 TRP S C     1 
ATOM   7944 O O     . TRP E 5 214 ? 135.211 100.661 102.826 1.00 11.74  ? 176 TRP S O     1 
ATOM   7945 C CB    . TRP E 5 214 ? 132.573 99.306  102.563 1.00 4.19   ? 176 TRP S CB    1 
ATOM   7946 C CG    . TRP E 5 214 ? 131.290 98.571  102.765 1.00 9.33   ? 176 TRP S CG    1 
ATOM   7947 C CD1   . TRP E 5 214 ? 130.059 99.116  102.977 1.00 2.13   ? 176 TRP S CD1   1 
ATOM   7948 C CD2   . TRP E 5 214 ? 131.106 97.151  102.764 1.00 9.84   ? 176 TRP S CD2   1 
ATOM   7949 N NE1   . TRP E 5 214 ? 129.120 98.125  103.113 1.00 0.13   ? 176 TRP S NE1   1 
ATOM   7950 C CE2   . TRP E 5 214 ? 129.737 96.909  102.986 1.00 6.30   ? 176 TRP S CE2   1 
ATOM   7951 C CE3   . TRP E 5 214 ? 131.966 96.062  102.599 1.00 6.24   ? 176 TRP S CE3   1 
ATOM   7952 C CZ2   . TRP E 5 214 ? 129.208 95.622  103.047 1.00 5.57   ? 176 TRP S CZ2   1 
ATOM   7953 C CZ3   . TRP E 5 214 ? 131.439 94.786  102.660 1.00 7.69   ? 176 TRP S CZ3   1 
ATOM   7954 C CH2   . TRP E 5 214 ? 130.074 94.577  102.883 1.00 10.04  ? 176 TRP S CH2   1 
ATOM   7955 N N     . PHE E 5 215 ? 135.843 98.589  103.509 1.00 2.26   ? 177 PHE S N     1 
ATOM   7956 C CA    . PHE E 5 215 ? 137.240 98.685  103.118 1.00 3.83   ? 177 PHE S CA    1 
ATOM   7957 C C     . PHE E 5 215 ? 137.533 97.670  102.023 1.00 6.47   ? 177 PHE S C     1 
ATOM   7958 O O     . PHE E 5 215 ? 136.915 96.604  101.964 1.00 21.00  ? 177 PHE S O     1 
ATOM   7959 C CB    . PHE E 5 215 ? 138.188 98.414  104.297 1.00 10.52  ? 177 PHE S CB    1 
ATOM   7960 C CG    . PHE E 5 215 ? 137.982 99.320  105.473 1.00 3.73   ? 177 PHE S CG    1 
ATOM   7961 C CD1   . PHE E 5 215 ? 138.635 100.536 105.549 1.00 4.39   ? 177 PHE S CD1   1 
ATOM   7962 C CD2   . PHE E 5 215 ? 137.152 98.944  106.513 1.00 0.00   ? 177 PHE S CD2   1 
ATOM   7963 C CE1   . PHE E 5 215 ? 138.453 101.366 106.635 1.00 2.77   ? 177 PHE S CE1   1 
ATOM   7964 C CE2   . PHE E 5 215 ? 136.967 99.768  107.600 1.00 0.00   ? 177 PHE S CE2   1 
ATOM   7965 C CZ    . PHE E 5 215 ? 137.616 100.982 107.661 1.00 0.00   ? 177 PHE S CZ    1 
ATOM   7966 N N     . LEU E 5 216 ? 138.492 98.002  101.165 1.00 1.01   ? 178 LEU S N     1 
ATOM   7967 C CA    . LEU E 5 216 ? 138.984 97.093  100.140 1.00 7.22   ? 178 LEU S CA    1 
ATOM   7968 C C     . LEU E 5 216 ? 140.475 96.876  100.346 1.00 12.05  ? 178 LEU S C     1 
ATOM   7969 O O     . LEU E 5 216 ? 141.233 97.843  100.473 1.00 29.81  ? 178 LEU S O     1 
ATOM   7970 C CB    . LEU E 5 216 ? 138.720 97.643  98.737  1.00 18.27  ? 178 LEU S CB    1 
ATOM   7971 C CG    . LEU E 5 216 ? 139.537 97.040  97.592  1.00 16.68  ? 178 LEU S CG    1 
ATOM   7972 C CD1   . LEU E 5 216 ? 139.118 95.604  97.330  1.00 18.37  ? 178 LEU S CD1   1 
ATOM   7973 C CD2   . LEU E 5 216 ? 139.392 97.881  96.335  1.00 17.78  ? 178 LEU S CD2   1 
ATOM   7974 N N     . GLN E 5 217 ? 140.892 95.613  100.382 1.00 11.66  ? 179 GLN S N     1 
ATOM   7975 C CA    . GLN E 5 217 ? 142.301 95.253  100.483 1.00 14.99  ? 179 GLN S CA    1 
ATOM   7976 C C     . GLN E 5 217 ? 142.685 94.503  99.216  1.00 22.18  ? 179 GLN S C     1 
ATOM   7977 O O     . GLN E 5 217 ? 142.213 93.385  98.983  1.00 29.58  ? 179 GLN S O     1 
ATOM   7978 C CB    . GLN E 5 217 ? 142.571 94.407  101.726 1.00 13.52  ? 179 GLN S CB    1 
ATOM   7979 C CG    . GLN E 5 217 ? 144.048 94.200  102.008 1.00 15.05  ? 179 GLN S CG    1 
ATOM   7980 C CD    . GLN E 5 217 ? 144.298 93.210  103.122 1.00 14.82  ? 179 GLN S CD    1 
ATOM   7981 O OE1   . GLN E 5 217 ? 143.394 92.490  103.544 1.00 20.68  ? 179 GLN S OE1   1 
ATOM   7982 N NE2   . GLN E 5 217 ? 145.533 93.166  103.606 1.00 20.45  ? 179 GLN S NE2   1 
ATOM   7983 N N     . ARG E 5 218 ? 143.519 95.127  98.394  1.00 22.21  ? 180 ARG S N     1 
ATOM   7984 C CA    . ARG E 5 218 ? 144.012 94.501  97.182  1.00 24.96  ? 180 ARG S CA    1 
ATOM   7985 C C     . ARG E 5 218 ? 145.197 93.595  97.501  1.00 29.50  ? 180 ARG S C     1 
ATOM   7986 O O     . ARG E 5 218 ? 145.878 93.784  98.512  1.00 30.65  ? 180 ARG S O     1 
ATOM   7987 C CB    . ARG E 5 218 ? 144.410 95.571  96.170  1.00 28.19  ? 180 ARG S CB    1 
ATOM   7988 C CG    . ARG E 5 218 ? 143.243 96.421  95.696  1.00 24.89  ? 180 ARG S CG    1 
ATOM   7989 C CD    . ARG E 5 218 ? 143.667 97.414  94.629  1.00 28.89  ? 180 ARG S CD    1 
ATOM   7990 N NE    . ARG E 5 218 ? 142.613 98.379  94.339  1.00 33.20  ? 180 ARG S NE    1 
ATOM   7991 C CZ    . ARG E 5 218 ? 142.377 99.469  95.057  1.00 32.47  ? 180 ARG S CZ    1 
ATOM   7992 N NH1   . ARG E 5 218 ? 143.106 99.769  96.119  1.00 27.95  ? 180 ARG S NH1   1 
ATOM   7993 N NH2   . ARG E 5 218 ? 141.385 100.279 94.699  1.00 29.55  ? 180 ARG S NH2   1 
ATOM   7994 N N     . PRO E 5 219 ? 145.451 92.587  96.666  1.00 28.87  ? 181 PRO S N     1 
ATOM   7995 C CA    . PRO E 5 219 ? 146.585 91.684  96.920  1.00 30.45  ? 181 PRO S CA    1 
ATOM   7996 C C     . PRO E 5 219 ? 147.901 92.444  96.965  1.00 28.93  ? 181 PRO S C     1 
ATOM   7997 O O     . PRO E 5 219 ? 148.274 93.137  96.016  1.00 26.12  ? 181 PRO S O     1 
ATOM   7998 C CB    . PRO E 5 219 ? 146.529 90.710  95.737  1.00 30.74  ? 181 PRO S CB    1 
ATOM   7999 C CG    . PRO E 5 219 ? 145.107 90.738  95.295  1.00 27.91  ? 181 PRO S CG    1 
ATOM   8000 C CD    . PRO E 5 219 ? 144.638 92.143  95.520  1.00 25.89  ? 181 PRO S CD    1 
ATOM   8001 N N     . GLY E 5 220 ? 148.606 92.309  98.087  1.00 27.01  ? 182 GLY S N     1 
ATOM   8002 C CA    . GLY E 5 220 ? 149.867 92.994  98.278  1.00 26.64  ? 182 GLY S CA    1 
ATOM   8003 C C     . GLY E 5 220 ? 149.758 94.440  98.702  1.00 29.74  ? 182 GLY S C     1 
ATOM   8004 O O     . GLY E 5 220 ? 150.782 95.130  98.753  1.00 26.82  ? 182 GLY S O     1 
ATOM   8005 N N     . GLN E 5 221 ? 148.556 94.922  99.009  1.00 29.74  ? 183 GLN S N     1 
ATOM   8006 C CA    . GLN E 5 221 ? 148.344 96.311  99.382  1.00 27.07  ? 183 GLN S CA    1 
ATOM   8007 C C     . GLN E 5 221 ? 147.591 96.383  100.703 1.00 23.64  ? 183 GLN S C     1 
ATOM   8008 O O     . GLN E 5 221 ? 146.886 95.451  101.095 1.00 20.34  ? 183 GLN S O     1 
ATOM   8009 C CB    . GLN E 5 221 ? 147.567 97.074  98.298  1.00 21.32  ? 183 GLN S CB    1 
ATOM   8010 C CG    . GLN E 5 221 ? 148.267 97.129  96.951  1.00 27.67  ? 183 GLN S CG    1 
ATOM   8011 C CD    . GLN E 5 221 ? 147.568 98.049  95.970  1.00 36.75  ? 183 GLN S CD    1 
ATOM   8012 O OE1   . GLN E 5 221 ? 146.511 98.606  96.268  1.00 37.09  ? 183 GLN S OE1   1 
ATOM   8013 N NE2   . GLN E 5 221 ? 148.156 98.213  94.791  1.00 28.77  ? 183 GLN S NE2   1 
ATOM   8014 N N     . SER E 5 222 ? 147.759 97.510  101.390 1.00 17.39  ? 184 SER S N     1 
ATOM   8015 C CA    . SER E 5 222 ? 147.044 97.753  102.629 1.00 13.75  ? 184 SER S CA    1 
ATOM   8016 C C     . SER E 5 222 ? 145.569 98.025  102.343 1.00 15.79  ? 184 SER S C     1 
ATOM   8017 O O     . SER E 5 222 ? 145.209 98.449  101.242 1.00 17.94  ? 184 SER S O     1 
ATOM   8018 C CB    . SER E 5 222 ? 147.665 98.933  103.373 1.00 13.86  ? 184 SER S CB    1 
ATOM   8019 O OG    . SER E 5 222 ? 147.680 100.095 102.563 1.00 17.65  ? 184 SER S OG    1 
ATOM   8020 N N     . PRO E 5 223 ? 144.693 97.771  103.316 1.00 12.48  ? 185 PRO S N     1 
ATOM   8021 C CA    . PRO E 5 223 ? 143.267 98.053  103.109 1.00 3.72   ? 185 PRO S CA    1 
ATOM   8022 C C     . PRO E 5 223 ? 143.024 99.528  102.827 1.00 5.59   ? 185 PRO S C     1 
ATOM   8023 O O     . PRO E 5 223 ? 143.675 100.407 103.395 1.00 13.65  ? 185 PRO S O     1 
ATOM   8024 C CB    . PRO E 5 223 ? 142.623 97.618  104.430 1.00 2.74   ? 185 PRO S CB    1 
ATOM   8025 C CG    . PRO E 5 223 ? 143.576 96.634  105.009 1.00 12.19  ? 185 PRO S CG    1 
ATOM   8026 C CD    . PRO E 5 223 ? 144.941 97.093  104.600 1.00 15.98  ? 185 PRO S CD    1 
ATOM   8027 N N     . GLN E 5 224 ? 142.074 99.791  101.935 1.00 13.12  ? 186 GLN S N     1 
ATOM   8028 C CA    . GLN E 5 224 ? 141.717 101.141 101.525 1.00 9.33   ? 186 GLN S CA    1 
ATOM   8029 C C     . GLN E 5 224 ? 140.250 101.386 101.840 1.00 6.18   ? 186 GLN S C     1 
ATOM   8030 O O     . GLN E 5 224 ? 139.398 100.548 101.529 1.00 11.29  ? 186 GLN S O     1 
ATOM   8031 C CB    . GLN E 5 224 ? 141.977 101.351 100.032 1.00 9.88   ? 186 GLN S CB    1 
ATOM   8032 C CG    . GLN E 5 224 ? 141.664 102.752 99.539  1.00 21.05  ? 186 GLN S CG    1 
ATOM   8033 C CD    . GLN E 5 224 ? 141.990 102.939 98.072  1.00 26.39  ? 186 GLN S CD    1 
ATOM   8034 O OE1   . GLN E 5 224 ? 142.443 102.011 97.402  1.00 22.51  ? 186 GLN S OE1   1 
ATOM   8035 N NE2   . GLN E 5 224 ? 141.756 104.143 97.563  1.00 21.94  ? 186 GLN S NE2   1 
ATOM   8036 N N     . LEU E 5 225 ? 139.959 102.531 102.452 1.00 3.35   ? 187 LEU S N     1 
ATOM   8037 C CA    . LEU E 5 225 ? 138.581 102.868 102.775 1.00 2.84   ? 187 LEU S CA    1 
ATOM   8038 C C     . LEU E 5 225 ? 137.793 103.146 101.503 1.00 13.29  ? 187 LEU S C     1 
ATOM   8039 O O     . LEU E 5 225 ? 138.225 103.924 100.647 1.00 18.38  ? 187 LEU S O     1 
ATOM   8040 C CB    . LEU E 5 225 ? 138.529 104.082 103.701 1.00 0.84   ? 187 LEU S CB    1 
ATOM   8041 C CG    . LEU E 5 225 ? 137.124 104.602 104.017 1.00 2.02   ? 187 LEU S CG    1 
ATOM   8042 C CD1   . LEU E 5 225 ? 136.371 103.615 104.892 1.00 0.79   ? 187 LEU S CD1   1 
ATOM   8043 C CD2   . LEU E 5 225 ? 137.174 105.971 104.673 1.00 0.05   ? 187 LEU S CD2   1 
ATOM   8044 N N     . LEU E 5 226 ? 136.633 102.507 101.380 1.00 4.49   ? 188 LEU S N     1 
ATOM   8045 C CA    . LEU E 5 226 ? 135.708 102.759 100.285 1.00 0.00   ? 188 LEU S CA    1 
ATOM   8046 C C     . LEU E 5 226 ? 134.485 103.539 100.734 1.00 7.79   ? 188 LEU S C     1 
ATOM   8047 O O     . LEU E 5 226 ? 134.142 104.560 100.131 1.00 21.22  ? 188 LEU S O     1 
ATOM   8048 C CB    . LEU E 5 226 ? 135.261 101.438 99.646  1.00 5.11   ? 188 LEU S CB    1 
ATOM   8049 C CG    . LEU E 5 226 ? 136.314 100.528 99.020  1.00 9.12   ? 188 LEU S CG    1 
ATOM   8050 C CD1   . LEU E 5 226 ? 135.625 99.347  98.368  1.00 13.87  ? 188 LEU S CD1   1 
ATOM   8051 C CD2   . LEU E 5 226 ? 137.159 101.285 98.012  1.00 14.68  ? 188 LEU S CD2   1 
ATOM   8052 N N     . ILE E 5 227 ? 133.816 103.080 101.787 1.00 7.61   ? 189 ILE S N     1 
ATOM   8053 C CA    . ILE E 5 227 ? 132.581 103.695 102.262 1.00 0.08   ? 189 ILE S CA    1 
ATOM   8054 C C     . ILE E 5 227 ? 132.692 103.920 103.761 1.00 0.00   ? 189 ILE S C     1 
ATOM   8055 O O     . ILE E 5 227 ? 133.139 103.034 104.494 1.00 6.45   ? 189 ILE S O     1 
ATOM   8056 C CB    . ILE E 5 227 ? 131.350 102.821 101.934 1.00 1.07   ? 189 ILE S CB    1 
ATOM   8057 C CG1   . ILE E 5 227 ? 131.187 102.662 100.420 1.00 8.50   ? 189 ILE S CG1   1 
ATOM   8058 C CG2   . ILE E 5 227 ? 130.088 103.408 102.548 1.00 6.92   ? 189 ILE S CG2   1 
ATOM   8059 C CD1   . ILE E 5 227 ? 130.603 103.876 99.736  1.00 12.15  ? 189 ILE S CD1   1 
ATOM   8060 N N     . TYR E 5 228 ? 132.289 105.101 104.220 1.00 0.00   ? 190 TYR S N     1 
ATOM   8061 C CA    . TYR E 5 228 ? 132.228 105.388 105.646 1.00 0.00   ? 190 TYR S CA    1 
ATOM   8062 C C     . TYR E 5 228 ? 130.808 105.770 106.035 1.00 0.00   ? 190 TYR S C     1 
ATOM   8063 O O     . TYR E 5 228 ? 130.128 106.503 105.310 1.00 20.12  ? 190 TYR S O     1 
ATOM   8064 C CB    . TYR E 5 228 ? 133.219 106.491 106.051 1.00 10.82  ? 190 TYR S CB    1 
ATOM   8065 C CG    . TYR E 5 228 ? 133.071 107.818 105.344 1.00 0.00   ? 190 TYR S CG    1 
ATOM   8066 C CD1   . TYR E 5 228 ? 133.581 108.010 104.068 1.00 0.00   ? 190 TYR S CD1   1 
ATOM   8067 C CD2   . TYR E 5 228 ? 132.454 108.892 105.970 1.00 0.00   ? 190 TYR S CD2   1 
ATOM   8068 C CE1   . TYR E 5 228 ? 133.461 109.226 103.427 1.00 7.87   ? 190 TYR S CE1   1 
ATOM   8069 C CE2   . TYR E 5 228 ? 132.331 110.112 105.338 1.00 1.62   ? 190 TYR S CE2   1 
ATOM   8070 C CZ    . TYR E 5 228 ? 132.835 110.274 104.067 1.00 7.84   ? 190 TYR S CZ    1 
ATOM   8071 O OH    . TYR E 5 228 ? 132.712 111.487 103.432 1.00 13.06  ? 190 TYR S OH    1 
ATOM   8072 N N     . ARG E 5 229 ? 130.367 105.252 107.183 1.00 2.23   ? 191 ARG S N     1 
ATOM   8073 C CA    . ARG E 5 229 ? 129.009 105.448 107.695 1.00 1.23   ? 191 ARG S CA    1 
ATOM   8074 C C     . ARG E 5 229 ? 127.949 104.931 106.723 1.00 7.01   ? 191 ARG S C     1 
ATOM   8075 O O     . ARG E 5 229 ? 126.863 105.506 106.609 1.00 10.62  ? 191 ARG S O     1 
ATOM   8076 C CB    . ARG E 5 229 ? 128.753 106.913 108.058 1.00 7.98   ? 191 ARG S CB    1 
ATOM   8077 C CG    . ARG E 5 229 ? 129.385 107.320 109.381 1.00 1.88   ? 191 ARG S CG    1 
ATOM   8078 C CD    . ARG E 5 229 ? 128.965 108.715 109.802 1.00 4.86   ? 191 ARG S CD    1 
ATOM   8079 N NE    . ARG E 5 229 ? 129.498 109.736 108.910 1.00 10.75  ? 191 ARG S NE    1 
ATOM   8080 C CZ    . ARG E 5 229 ? 130.703 110.277 109.025 1.00 1.97   ? 191 ARG S CZ    1 
ATOM   8081 N NH1   . ARG E 5 229 ? 131.534 109.914 109.988 1.00 0.32   ? 191 ARG S NH1   1 
ATOM   8082 N NH2   . ARG E 5 229 ? 131.084 111.204 108.152 1.00 5.67   ? 191 ARG S NH2   1 
ATOM   8083 N N     . MET E 5 230 ? 128.284 103.861 105.997 1.00 7.24   ? 192 MET S N     1 
ATOM   8084 C CA    . MET E 5 230 ? 127.335 103.009 105.284 1.00 0.00   ? 192 MET S CA    1 
ATOM   8085 C C     . MET E 5 230 ? 126.750 103.661 104.035 1.00 13.22  ? 192 MET S C     1 
ATOM   8086 O O     . MET E 5 230 ? 126.117 102.984 103.218 1.00 22.03  ? 192 MET S O     1 
ATOM   8087 C CB    . MET E 5 230 ? 126.209 102.585 106.236 1.00 8.27   ? 192 MET S CB    1 
ATOM   8088 C CG    . MET E 5 230 ? 125.279 101.505 105.709 1.00 16.92  ? 192 MET S CG    1 
ATOM   8089 S SD    . MET E 5 230 ? 123.566 101.798 106.187 1.00 22.98  ? 192 MET S SD    1 
ATOM   8090 C CE    . MET E 5 230 ? 123.053 102.952 104.918 1.00 4.49   ? 192 MET S CE    1 
ATOM   8091 N N     . SER E 5 231 ? 126.977 104.959 103.846 1.00 16.30  ? 193 SER S N     1 
ATOM   8092 C CA    . SER E 5 231 ? 126.430 105.639 102.675 1.00 8.57   ? 193 SER S CA    1 
ATOM   8093 C C     . SER E 5 231 ? 127.381 106.617 102.009 1.00 13.79  ? 193 SER S C     1 
ATOM   8094 O O     . SER E 5 231 ? 127.104 107.031 100.878 1.00 8.89   ? 193 SER S O     1 
ATOM   8095 C CB    . SER E 5 231 ? 125.139 106.381 103.042 1.00 7.91   ? 193 SER S CB    1 
ATOM   8096 O OG    . SER E 5 231 ? 125.398 107.443 103.944 1.00 17.63  ? 193 SER S OG    1 
ATOM   8097 N N     . ASN E 5 232 ? 128.484 107.000 102.641 1.00 5.98   ? 194 ASN S N     1 
ATOM   8098 C CA    . ASN E 5 232 ? 129.340 108.067 102.144 1.00 6.92   ? 194 ASN S CA    1 
ATOM   8099 C C     . ASN E 5 232 ? 130.546 107.478 101.427 1.00 9.76   ? 194 ASN S C     1 
ATOM   8100 O O     . ASN E 5 232 ? 131.259 106.639 101.986 1.00 5.77   ? 194 ASN S O     1 
ATOM   8101 C CB    . ASN E 5 232 ? 129.792 108.969 103.291 1.00 0.00   ? 194 ASN S CB    1 
ATOM   8102 C CG    . ASN E 5 232 ? 128.640 109.702 103.944 1.00 16.80  ? 194 ASN S CG    1 
ATOM   8103 O OD1   . ASN E 5 232 ? 127.626 109.981 103.306 1.00 26.50  ? 194 ASN S OD1   1 
ATOM   8104 N ND2   . ASN E 5 232 ? 128.787 110.011 105.226 1.00 17.58  ? 194 ASN S ND2   1 
ATOM   8105 N N     . LEU E 5 233 ? 130.769 107.923 100.194 1.00 16.16  ? 195 LEU S N     1 
ATOM   8106 C CA    . LEU E 5 233 ? 131.909 107.471 99.411  1.00 7.41   ? 195 LEU S CA    1 
ATOM   8107 C C     . LEU E 5 233 ? 133.168 108.203 99.857  1.00 6.48   ? 195 LEU S C     1 
ATOM   8108 O O     . LEU E 5 233 ? 133.179 109.434 99.957  1.00 9.53   ? 195 LEU S O     1 
ATOM   8109 C CB    . LEU E 5 233 ? 131.653 107.706 97.923  1.00 10.21  ? 195 LEU S CB    1 
ATOM   8110 C CG    . LEU E 5 233 ? 132.580 107.018 96.922  1.00 11.64  ? 195 LEU S CG    1 
ATOM   8111 C CD1   . LEU E 5 233 ? 132.520 105.511 97.083  1.00 15.85  ? 195 LEU S CD1   1 
ATOM   8112 C CD2   . LEU E 5 233 ? 132.207 107.420 95.506  1.00 11.15  ? 195 LEU S CD2   1 
ATOM   8113 N N     . ALA E 5 234 ? 134.227 107.445 100.126 1.00 6.58   ? 196 ALA S N     1 
ATOM   8114 C CA    . ALA E 5 234 ? 135.474 108.036 100.585 1.00 12.78  ? 196 ALA S CA    1 
ATOM   8115 C C     . ALA E 5 234 ? 136.142 108.826 99.463  1.00 19.61  ? 196 ALA S C     1 
ATOM   8116 O O     . ALA E 5 234 ? 135.893 108.606 98.274  1.00 24.56  ? 196 ALA S O     1 
ATOM   8117 C CB    . ALA E 5 234 ? 136.422 106.956 101.105 1.00 3.79   ? 196 ALA S CB    1 
ATOM   8118 N N     . SER E 5 235 ? 136.996 109.766 99.860  1.00 17.85  ? 197 SER S N     1 
ATOM   8119 C CA    . SER E 5 235 ? 137.693 110.602 98.893  1.00 20.30  ? 197 SER S CA    1 
ATOM   8120 C C     . SER E 5 235 ? 138.663 109.769 98.065  1.00 28.90  ? 197 SER S C     1 
ATOM   8121 O O     . SER E 5 235 ? 139.382 108.915 98.591  1.00 28.40  ? 197 SER S O     1 
ATOM   8122 C CB    . SER E 5 235 ? 138.440 111.728 99.606  1.00 20.58  ? 197 SER S CB    1 
ATOM   8123 O OG    . SER E 5 235 ? 137.547 112.540 100.347 1.00 22.47  ? 197 SER S OG    1 
ATOM   8124 N N     . GLY E 5 236 ? 138.680 110.025 96.759  1.00 22.90  ? 198 GLY S N     1 
ATOM   8125 C CA    . GLY E 5 236 ? 139.515 109.281 95.843  1.00 22.82  ? 198 GLY S CA    1 
ATOM   8126 C C     . GLY E 5 236 ? 138.918 107.985 95.344  1.00 24.82  ? 198 GLY S C     1 
ATOM   8127 O O     . GLY E 5 236 ? 139.529 107.330 94.490  1.00 26.32  ? 198 GLY S O     1 
ATOM   8128 N N     . VAL E 5 237 ? 137.751 107.594 95.845  1.00 21.20  ? 199 VAL S N     1 
ATOM   8129 C CA    . VAL E 5 237 ? 137.083 106.367 95.422  1.00 24.21  ? 199 VAL S CA    1 
ATOM   8130 C C     . VAL E 5 237 ? 136.112 106.703 94.296  1.00 22.48  ? 199 VAL S C     1 
ATOM   8131 O O     . VAL E 5 237 ? 135.297 107.626 94.439  1.00 21.57  ? 199 VAL S O     1 
ATOM   8132 C CB    . VAL E 5 237 ? 136.365 105.690 96.599  1.00 17.46  ? 199 VAL S CB    1 
ATOM   8133 C CG1   . VAL E 5 237 ? 135.903 104.298 96.210  1.00 17.46  ? 199 VAL S CG1   1 
ATOM   8134 C CG2   . VAL E 5 237 ? 137.282 105.626 97.806  1.00 16.65  ? 199 VAL S CG2   1 
ATOM   8135 N N     . PRO E 5 238 ? 136.165 105.999 93.169  1.00 29.64  ? 200 PRO S N     1 
ATOM   8136 C CA    . PRO E 5 238 ? 135.239 106.289 92.068  1.00 34.99  ? 200 PRO S CA    1 
ATOM   8137 C C     . PRO E 5 238 ? 133.805 105.948 92.445  1.00 30.30  ? 200 PRO S C     1 
ATOM   8138 O O     . PRO E 5 238 ? 133.531 105.184 93.372  1.00 27.94  ? 200 PRO S O     1 
ATOM   8139 C CB    . PRO E 5 238 ? 135.748 105.398 90.931  1.00 34.65  ? 200 PRO S CB    1 
ATOM   8140 C CG    . PRO E 5 238 ? 136.481 104.296 91.617  1.00 31.40  ? 200 PRO S CG    1 
ATOM   8141 C CD    . PRO E 5 238 ? 137.101 104.913 92.834  1.00 28.27  ? 200 PRO S CD    1 
ATOM   8142 N N     . ASP E 5 239 ? 132.876 106.536 91.694  1.00 32.46  ? 201 ASP S N     1 
ATOM   8143 C CA    . ASP E 5 239 ? 131.439 106.386 91.926  1.00 36.87  ? 201 ASP S CA    1 
ATOM   8144 C C     . ASP E 5 239 ? 130.916 104.974 91.638  1.00 37.67  ? 201 ASP S C     1 
ATOM   8145 O O     . ASP E 5 239 ? 129.695 104.775 91.705  1.00 37.33  ? 201 ASP S O     1 
ATOM   8146 C CB    . ASP E 5 239 ? 130.670 107.414 91.092  1.00 39.16  ? 201 ASP S CB    1 
ATOM   8147 C CG    . ASP E 5 239 ? 130.907 107.257 89.598  1.00 45.00  ? 201 ASP S CG    1 
ATOM   8148 O OD1   . ASP E 5 239 ? 131.713 106.391 89.199  1.00 45.46  ? 201 ASP S OD1   1 
ATOM   8149 O OD2   . ASP E 5 239 ? 130.282 108.008 88.819  1.00 42.18  ? 201 ASP S OD2   1 
ATOM   8150 N N     . ARG E 5 240 ? 131.784 104.011 91.317  1.00 40.54  ? 202 ARG S N     1 
ATOM   8151 C CA    . ARG E 5 240 ? 131.330 102.640 91.112  1.00 40.83  ? 202 ARG S CA    1 
ATOM   8152 C C     . ARG E 5 240 ? 130.746 102.055 92.391  1.00 39.79  ? 202 ARG S C     1 
ATOM   8153 O O     . ARG E 5 240 ? 129.718 101.367 92.358  1.00 38.78  ? 202 ARG S O     1 
ATOM   8154 C CB    . ARG E 5 240 ? 132.488 101.775 90.615  1.00 41.77  ? 202 ARG S CB    1 
ATOM   8155 C CG    . ARG E 5 240 ? 133.120 102.254 89.321  1.00 43.26  ? 202 ARG S CG    1 
ATOM   8156 C CD    . ARG E 5 240 ? 134.042 101.194 88.740  1.00 45.20  ? 202 ARG S CD    1 
ATOM   8157 N NE    . ARG E 5 240 ? 135.174 100.915 89.616  1.00 36.38  ? 202 ARG S NE    1 
ATOM   8158 C CZ    . ARG E 5 240 ? 136.357 101.504 89.521  1.00 37.53  ? 202 ARG S CZ    1 
ATOM   8159 N NH1   . ARG E 5 240 ? 136.601 102.421 88.600  1.00 36.69  ? 202 ARG S NH1   1 
ATOM   8160 N NH2   . ARG E 5 240 ? 137.321 101.165 90.372  1.00 42.30  ? 202 ARG S NH2   1 
ATOM   8161 N N     . PHE E 5 241 ? 131.385 102.318 93.528  1.00 29.93  ? 203 PHE S N     1 
ATOM   8162 C CA    . PHE E 5 241 ? 130.988 101.735 94.801  1.00 23.27  ? 203 PHE S CA    1 
ATOM   8163 C C     . PHE E 5 241 ? 129.869 102.555 95.431  1.00 25.47  ? 203 PHE S C     1 
ATOM   8164 O O     . PHE E 5 241 ? 129.956 103.784 95.505  1.00 27.82  ? 203 PHE S O     1 
ATOM   8165 C CB    . PHE E 5 241 ? 132.181 101.659 95.755  1.00 27.61  ? 203 PHE S CB    1 
ATOM   8166 C CG    . PHE E 5 241 ? 133.383 100.969 95.174  1.00 27.86  ? 203 PHE S CG    1 
ATOM   8167 C CD1   . PHE E 5 241 ? 134.314 101.676 94.430  1.00 28.19  ? 203 PHE S CD1   1 
ATOM   8168 C CD2   . PHE E 5 241 ? 133.586 99.616  95.377  1.00 32.25  ? 203 PHE S CD2   1 
ATOM   8169 C CE1   . PHE E 5 241 ? 135.420 101.044 93.897  1.00 30.03  ? 203 PHE S CE1   1 
ATOM   8170 C CE2   . PHE E 5 241 ? 134.691 98.979  94.847  1.00 28.37  ? 203 PHE S CE2   1 
ATOM   8171 C CZ    . PHE E 5 241 ? 135.609 99.694  94.106  1.00 27.50  ? 203 PHE S CZ    1 
ATOM   8172 N N     . SER E 5 242 ? 128.820 101.868 95.880  1.00 24.93  ? 204 SER S N     1 
ATOM   8173 C CA    . SER E 5 242 ? 127.717 102.504 96.585  1.00 20.89  ? 204 SER S CA    1 
ATOM   8174 C C     . SER E 5 242 ? 127.325 101.642 97.775  1.00 21.04  ? 204 SER S C     1 
ATOM   8175 O O     . SER E 5 242 ? 127.268 100.415 97.668  1.00 26.62  ? 204 SER S O     1 
ATOM   8176 C CB    . SER E 5 242 ? 126.508 102.717 95.666  1.00 23.76  ? 204 SER S CB    1 
ATOM   8177 O OG    . SER E 5 242 ? 125.969 101.479 95.237  1.00 24.74  ? 204 SER S OG    1 
ATOM   8178 N N     . GLY E 5 243 ? 127.054 102.284 98.904  1.00 17.47  ? 205 GLY S N     1 
ATOM   8179 C CA    . GLY E 5 243 ? 126.694 101.591 100.133 1.00 16.05  ? 205 GLY S CA    1 
ATOM   8180 C C     . GLY E 5 243 ? 125.220 101.774 100.449 1.00 19.26  ? 205 GLY S C     1 
ATOM   8181 O O     . GLY E 5 243 ? 124.662 102.854 100.239 1.00 23.93  ? 205 GLY S O     1 
ATOM   8182 N N     . SER E 5 244 ? 124.597 100.711 100.954 1.00 16.46  ? 206 SER S N     1 
ATOM   8183 C CA    . SER E 5 244 ? 123.205 100.769 101.372 1.00 13.93  ? 206 SER S CA    1 
ATOM   8184 C C     . SER E 5 244 ? 123.014 99.830  102.552 1.00 17.77  ? 206 SER S C     1 
ATOM   8185 O O     . SER E 5 244 ? 123.806 98.912  102.770 1.00 27.63  ? 206 SER S O     1 
ATOM   8186 C CB    . SER E 5 244 ? 122.254 100.400 100.228 1.00 25.72  ? 206 SER S CB    1 
ATOM   8187 O OG    . SER E 5 244 ? 122.184 98.995  100.058 1.00 24.94  ? 206 SER S OG    1 
ATOM   8188 N N     . GLY E 5 245 ? 121.955 100.068 103.316 1.00 16.01  ? 207 GLY S N     1 
ATOM   8189 C CA    . GLY E 5 245 ? 121.669 99.221  104.457 1.00 16.08  ? 207 GLY S CA    1 
ATOM   8190 C C     . GLY E 5 245 ? 120.337 99.564  105.079 1.00 19.08  ? 207 GLY S C     1 
ATOM   8191 O O     . GLY E 5 245 ? 119.777 100.641 104.849 1.00 22.86  ? 207 GLY S O     1 
ATOM   8192 N N     . SER E 5 246 ? 119.836 98.622  105.879 1.00 21.30  ? 208 SER S N     1 
ATOM   8193 C CA    . SER E 5 246 ? 118.570 98.775  106.584 1.00 20.96  ? 208 SER S CA    1 
ATOM   8194 C C     . SER E 5 246 ? 118.757 98.847  108.096 1.00 25.02  ? 208 SER S C     1 
ATOM   8195 O O     . SER E 5 246 ? 117.787 98.704  108.846 1.00 29.61  ? 208 SER S O     1 
ATOM   8196 C CB    . SER E 5 246 ? 117.620 97.632  106.222 1.00 22.55  ? 208 SER S CB    1 
ATOM   8197 O OG    . SER E 5 246 ? 117.417 97.562  104.822 1.00 23.70  ? 208 SER S OG    1 
ATOM   8198 N N     . GLY E 5 247 ? 119.986 99.065  108.557 1.00 13.55  ? 209 GLY S N     1 
ATOM   8199 C CA    . GLY E 5 247 ? 120.256 99.153  109.978 1.00 14.86  ? 209 GLY S CA    1 
ATOM   8200 C C     . GLY E 5 247 ? 121.041 97.974  110.513 1.00 19.23  ? 209 GLY S C     1 
ATOM   8201 O O     . GLY E 5 247 ? 121.949 98.148  111.330 1.00 14.09  ? 209 GLY S O     1 
ATOM   8202 N N     . THR E 5 248 ? 120.705 96.768  110.056 1.00 17.30  ? 210 THR S N     1 
ATOM   8203 C CA    . THR E 5 248 ? 121.403 95.559  110.479 1.00 21.02  ? 210 THR S CA    1 
ATOM   8204 C C     . THR E 5 248 ? 121.925 94.708  109.332 1.00 18.76  ? 210 THR S C     1 
ATOM   8205 O O     . THR E 5 248 ? 122.843 93.910  109.557 1.00 28.25  ? 210 THR S O     1 
ATOM   8206 C CB    . THR E 5 248 ? 120.493 94.691  111.363 1.00 24.93  ? 210 THR S CB    1 
ATOM   8207 O OG1   . THR E 5 248 ? 121.244 93.592  111.893 1.00 21.05  ? 210 THR S OG1   1 
ATOM   8208 C CG2   . THR E 5 248 ? 119.312 94.160  110.564 1.00 23.88  ? 210 THR S CG2   1 
ATOM   8209 N N     . ALA E 5 249 ? 121.384 94.842  108.124 1.00 13.55  ? 211 ALA S N     1 
ATOM   8210 C CA    . ALA E 5 249 ? 121.882 94.150  106.944 1.00 18.74  ? 211 ALA S CA    1 
ATOM   8211 C C     . ALA E 5 249 ? 122.300 95.193  105.921 1.00 19.14  ? 211 ALA S C     1 
ATOM   8212 O O     . ALA E 5 249 ? 121.554 96.142  105.659 1.00 22.17  ? 211 ALA S O     1 
ATOM   8213 C CB    . ALA E 5 249 ? 120.822 93.215  106.356 1.00 21.96  ? 211 ALA S CB    1 
ATOM   8214 N N     . PHE E 5 250 ? 123.488 95.022  105.348 1.00 13.03  ? 212 PHE S N     1 
ATOM   8215 C CA    . PHE E 5 250 ? 124.083 96.042  104.500 1.00 12.48  ? 212 PHE S CA    1 
ATOM   8216 C C     . PHE E 5 250 ? 124.614 95.423  103.217 1.00 21.14  ? 212 PHE S C     1 
ATOM   8217 O O     . PHE E 5 250 ? 124.999 94.252  103.184 1.00 26.75  ? 212 PHE S O     1 
ATOM   8218 C CB    . PHE E 5 250 ? 125.218 96.759  105.220 1.00 6.78   ? 212 PHE S CB    1 
ATOM   8219 C CG    . PHE E 5 250 ? 124.878 97.190  106.618 1.00 15.69  ? 212 PHE S CG    1 
ATOM   8220 C CD1   . PHE E 5 250 ? 124.132 98.332  106.845 1.00 12.73  ? 212 PHE S CD1   1 
ATOM   8221 C CD2   . PHE E 5 250 ? 125.313 96.453  107.707 1.00 14.21  ? 212 PHE S CD2   1 
ATOM   8222 C CE1   . PHE E 5 250 ? 123.823 98.728  108.130 1.00 15.72  ? 212 PHE S CE1   1 
ATOM   8223 C CE2   . PHE E 5 250 ? 125.006 96.844  108.993 1.00 8.62   ? 212 PHE S CE2   1 
ATOM   8224 C CZ    . PHE E 5 250 ? 124.261 97.984  109.205 1.00 9.01   ? 212 PHE S CZ    1 
ATOM   8225 N N     . THR E 5 251 ? 124.632 96.232  102.159 1.00 15.39  ? 213 THR S N     1 
ATOM   8226 C CA    . THR E 5 251 ? 125.150 95.831  100.861 1.00 15.28  ? 213 THR S CA    1 
ATOM   8227 C C     . THR E 5 251 ? 126.069 96.912  100.308 1.00 19.60  ? 213 THR S C     1 
ATOM   8228 O O     . THR E 5 251 ? 125.876 98.108  100.550 1.00 23.22  ? 213 THR S O     1 
ATOM   8229 C CB    . THR E 5 251 ? 124.024 95.559  99.846  1.00 17.49  ? 213 THR S CB    1 
ATOM   8230 O OG1   . THR E 5 251 ? 123.338 96.781  99.549  1.00 21.88  ? 213 THR S OG1   1 
ATOM   8231 C CG2   . THR E 5 251 ? 123.033 94.538  100.388 1.00 18.38  ? 213 THR S CG2   1 
ATOM   8232 N N     . LEU E 5 252 ? 127.083 96.466  99.573  1.00 19.79  ? 214 LEU S N     1 
ATOM   8233 C CA    . LEU E 5 252 ? 127.966 97.330  98.801  1.00 10.52  ? 214 LEU S CA    1 
ATOM   8234 C C     . LEU E 5 252 ? 127.883 96.892  97.348  1.00 21.91  ? 214 LEU S C     1 
ATOM   8235 O O     . LEU E 5 252 ? 128.181 95.736  97.028  1.00 27.42  ? 214 LEU S O     1 
ATOM   8236 C CB    . LEU E 5 252 ? 129.406 97.251  99.311  1.00 13.66  ? 214 LEU S CB    1 
ATOM   8237 C CG    . LEU E 5 252 ? 130.468 97.968  98.474  1.00 18.61  ? 214 LEU S CG    1 
ATOM   8238 C CD1   . LEU E 5 252 ? 130.441 99.465  98.734  1.00 16.25  ? 214 LEU S CD1   1 
ATOM   8239 C CD2   . LEU E 5 252 ? 131.846 97.398  98.753  1.00 11.19  ? 214 LEU S CD2   1 
ATOM   8240 N N     . THR E 5 253 ? 127.474 97.807  96.476  1.00 26.82  ? 215 THR S N     1 
ATOM   8241 C CA    . THR E 5 253 ? 127.258 97.518  95.066  1.00 30.84  ? 215 THR S CA    1 
ATOM   8242 C C     . THR E 5 253 ? 128.350 98.177  94.238  1.00 30.20  ? 215 THR S C     1 
ATOM   8243 O O     . THR E 5 253 ? 128.631 99.368  94.407  1.00 31.64  ? 215 THR S O     1 
ATOM   8244 C CB    . THR E 5 253 ? 125.882 98.008  94.608  1.00 22.68  ? 215 THR S CB    1 
ATOM   8245 N N     . ILE E 5 254 ? 128.961 97.398  93.349  1.00 35.64  ? 216 ILE S N     1 
ATOM   8246 C CA    . ILE E 5 254 ? 129.998 97.876  92.445  1.00 38.45  ? 216 ILE S CA    1 
ATOM   8247 C C     . ILE E 5 254 ? 129.487 97.704  91.023  1.00 41.60  ? 216 ILE S C     1 
ATOM   8248 O O     . ILE E 5 254 ? 129.103 96.597  90.625  1.00 43.59  ? 216 ILE S O     1 
ATOM   8249 C CB    . ILE E 5 254 ? 131.323 97.123  92.643  1.00 36.80  ? 216 ILE S CB    1 
ATOM   8250 C CG1   . ILE E 5 254 ? 131.579 96.877  94.131  1.00 37.20  ? 216 ILE S CG1   1 
ATOM   8251 C CG2   . ILE E 5 254 ? 132.472 97.898  92.020  1.00 34.36  ? 216 ILE S CG2   1 
ATOM   8252 C CD1   . ILE E 5 254 ? 132.725 95.929  94.401  1.00 34.16  ? 216 ILE S CD1   1 
ATOM   8253 N N     . SER E 5 255 ? 129.483 98.793  90.263  1.00 45.92  ? 217 SER S N     1 
ATOM   8254 C CA    . SER E 5 255 ? 129.057 98.788  88.873  1.00 45.54  ? 217 SER S CA    1 
ATOM   8255 C C     . SER E 5 255 ? 130.264 98.980  87.966  1.00 48.65  ? 217 SER S C     1 
ATOM   8256 O O     . SER E 5 255 ? 131.279 99.550  88.377  1.00 47.37  ? 217 SER S O     1 
ATOM   8257 C CB    . SER E 5 255 ? 128.022 99.886  88.610  1.00 44.25  ? 217 SER S CB    1 
ATOM   8258 O OG    . SER E 5 255 ? 126.874 99.707  89.420  1.00 41.43  ? 217 SER S OG    1 
ATOM   8259 N N     . ARG E 5 256 ? 130.133 98.503  86.729  1.00 50.33  ? 218 ARG S N     1 
ATOM   8260 C CA    . ARG E 5 256 ? 131.195 98.506  85.715  1.00 51.71  ? 218 ARG S CA    1 
ATOM   8261 C C     . ARG E 5 256 ? 132.555 98.178  86.336  1.00 50.66  ? 218 ARG S C     1 
ATOM   8262 O O     . ARG E 5 256 ? 133.536 98.909  86.205  1.00 47.93  ? 218 ARG S O     1 
ATOM   8263 C CB    . ARG E 5 256 ? 131.223 99.827  84.936  1.00 51.30  ? 218 ARG S CB    1 
ATOM   8264 C CG    . ARG E 5 256 ? 131.446 101.101 85.747  1.00 50.01  ? 218 ARG S CG    1 
ATOM   8265 C CD    . ARG E 5 256 ? 131.200 102.342 84.905  1.00 49.67  ? 218 ARG S CD    1 
ATOM   8266 N NE    . ARG E 5 256 ? 131.591 103.561 85.601  1.00 52.99  ? 218 ARG S NE    1 
ATOM   8267 C CZ    . ARG E 5 256 ? 130.826 104.206 86.472  1.00 54.26  ? 218 ARG S CZ    1 
ATOM   8268 N NH1   . ARG E 5 256 ? 129.615 103.773 86.781  1.00 52.34  ? 218 ARG S NH1   1 
ATOM   8269 N NH2   . ARG E 5 256 ? 131.288 105.313 87.046  1.00 51.60  ? 218 ARG S NH2   1 
ATOM   8270 N N     . LEU E 5 257 ? 132.587 97.037  87.019  1.00 51.50  ? 219 LEU S N     1 
ATOM   8271 C CA    . LEU E 5 257 ? 133.781 96.607  87.734  1.00 51.38  ? 219 LEU S CA    1 
ATOM   8272 C C     . LEU E 5 257 ? 134.923 96.316  86.766  1.00 50.33  ? 219 LEU S C     1 
ATOM   8273 O O     . LEU E 5 257 ? 134.713 95.791  85.669  1.00 54.66  ? 219 LEU S O     1 
ATOM   8274 C CB    . LEU E 5 257 ? 133.458 95.372  88.578  1.00 49.05  ? 219 LEU S CB    1 
ATOM   8275 C CG    . LEU E 5 257 ? 134.526 94.745  89.474  1.00 52.11  ? 219 LEU S CG    1 
ATOM   8276 C CD1   . LEU E 5 257 ? 133.892 94.254  90.758  1.00 50.58  ? 219 LEU S CD1   1 
ATOM   8277 C CD2   . LEU E 5 257 ? 135.191 93.582  88.759  1.00 50.19  ? 219 LEU S CD2   1 
ATOM   8278 N N     . GLU E 5 258 ? 136.136 96.670  87.177  1.00 48.05  ? 220 GLU S N     1 
ATOM   8279 C CA    . GLU E 5 258 ? 137.350 96.439  86.405  1.00 50.10  ? 220 GLU S CA    1 
ATOM   8280 C C     . GLU E 5 258 ? 138.298 95.541  87.202  1.00 51.29  ? 220 GLU S C     1 
ATOM   8281 O O     . GLU E 5 258 ? 137.942 94.997  88.249  1.00 49.81  ? 220 GLU S O     1 
ATOM   8282 C CB    . GLU E 5 258 ? 138.025 97.762  86.034  1.00 51.26  ? 220 GLU S CB    1 
ATOM   8283 C CG    . GLU E 5 258 ? 137.232 98.634  85.077  1.00 55.32  ? 220 GLU S CG    1 
ATOM   8284 C CD    . GLU E 5 258 ? 136.419 99.690  85.795  1.00 54.70  ? 220 GLU S CD    1 
ATOM   8285 O OE1   . GLU E 5 258 ? 136.481 99.738  87.041  1.00 50.27  ? 220 GLU S OE1   1 
ATOM   8286 O OE2   . GLU E 5 258 ? 135.723 100.474 85.116  1.00 51.99  ? 220 GLU S OE2   1 
ATOM   8287 N N     . ALA E 5 259 ? 139.516 95.384  86.690  1.00 51.92  ? 221 ALA S N     1 
ATOM   8288 C CA    . ALA E 5 259 ? 140.537 94.607  87.381  1.00 50.26  ? 221 ALA S CA    1 
ATOM   8289 C C     . ALA E 5 259 ? 141.276 95.410  88.443  1.00 50.83  ? 221 ALA S C     1 
ATOM   8290 O O     . ALA E 5 259 ? 142.119 94.843  89.147  1.00 48.03  ? 221 ALA S O     1 
ATOM   8291 C CB    . ALA E 5 259 ? 141.539 94.041  86.373  1.00 46.33  ? 221 ALA S CB    1 
ATOM   8292 N N     . GLU E 5 260 ? 140.987 96.704  88.577  1.00 50.12  ? 222 GLU S N     1 
ATOM   8293 C CA    . GLU E 5 260 ? 141.668 97.554  89.544  1.00 46.63  ? 222 GLU S CA    1 
ATOM   8294 C C     . GLU E 5 260 ? 141.065 97.484  90.941  1.00 46.74  ? 222 GLU S C     1 
ATOM   8295 O O     . GLU E 5 260 ? 141.697 97.956  91.892  1.00 47.96  ? 222 GLU S O     1 
ATOM   8296 C CB    . GLU E 5 260 ? 141.662 99.009  89.063  1.00 46.58  ? 222 GLU S CB    1 
ATOM   8297 C CG    . GLU E 5 260 ? 142.374 99.229  87.739  1.00 50.46  ? 222 GLU S CG    1 
ATOM   8298 C CD    . GLU E 5 260 ? 143.881 99.292  87.891  1.00 53.12  ? 222 GLU S CD    1 
ATOM   8299 O OE1   . GLU E 5 260 ? 144.360 99.407  89.039  1.00 51.47  ? 222 GLU S OE1   1 
ATOM   8300 O OE2   . GLU E 5 260 ? 144.588 99.227  86.863  1.00 48.81  ? 222 GLU S OE2   1 
ATOM   8301 N N     . ASP E 5 261 ? 139.873 96.915  91.092  1.00 43.81  ? 223 ASP S N     1 
ATOM   8302 C CA    . ASP E 5 261 ? 139.221 96.783  92.389  1.00 42.74  ? 223 ASP S CA    1 
ATOM   8303 C C     . ASP E 5 261 ? 138.952 95.319  92.716  1.00 37.00  ? 223 ASP S C     1 
ATOM   8304 O O     . ASP E 5 261 ? 137.875 94.953  93.190  1.00 35.30  ? 223 ASP S O     1 
ATOM   8305 C CB    . ASP E 5 261 ? 137.931 97.599  92.442  1.00 36.59  ? 223 ASP S CB    1 
ATOM   8306 C CG    . ASP E 5 261 ? 136.980 97.263  91.315  1.00 40.48  ? 223 ASP S CG    1 
ATOM   8307 O OD1   . ASP E 5 261 ? 137.449 96.767  90.272  1.00 43.24  ? 223 ASP S OD1   1 
ATOM   8308 O OD2   . ASP E 5 261 ? 135.763 97.494  91.472  1.00 44.05  ? 223 ASP S OD2   1 
ATOM   8309 N N     . VAL E 5 262 ? 139.939 94.465  92.462  1.00 37.54  ? 224 VAL S N     1 
ATOM   8310 C CA    . VAL E 5 262 ? 139.868 93.048  92.795  1.00 37.64  ? 224 VAL S CA    1 
ATOM   8311 C C     . VAL E 5 262 ? 140.629 92.825  94.093  1.00 39.50  ? 224 VAL S C     1 
ATOM   8312 O O     . VAL E 5 262 ? 141.808 93.184  94.201  1.00 39.51  ? 224 VAL S O     1 
ATOM   8313 C CB    . VAL E 5 262 ? 140.441 92.179  91.662  1.00 40.63  ? 224 VAL S CB    1 
ATOM   8314 C CG1   . VAL E 5 262 ? 140.612 90.743  92.127  1.00 38.62  ? 224 VAL S CG1   1 
ATOM   8315 C CG2   . VAL E 5 262 ? 139.540 92.244  90.438  1.00 37.85  ? 224 VAL S CG2   1 
ATOM   8316 N N     . GLY E 5 263 ? 139.958 92.238  95.078  1.00 30.05  ? 225 GLY S N     1 
ATOM   8317 C CA    . GLY E 5 263 ? 140.576 92.028  96.373  1.00 26.09  ? 225 GLY S CA    1 
ATOM   8318 C C     . GLY E 5 263 ? 139.560 91.503  97.367  1.00 29.48  ? 225 GLY S C     1 
ATOM   8319 O O     . GLY E 5 263 ? 138.549 90.912  96.985  1.00 31.01  ? 225 GLY S O     1 
ATOM   8320 N N     . VAL E 5 264 ? 139.847 91.729  98.645  1.00 25.52  ? 226 VAL S N     1 
ATOM   8321 C CA    . VAL E 5 264 ? 138.992 91.278  99.736  1.00 19.42  ? 226 VAL S CA    1 
ATOM   8322 C C     . VAL E 5 264 ? 138.286 92.487  100.331 1.00 15.71  ? 226 VAL S C     1 
ATOM   8323 O O     . VAL E 5 264 ? 138.925 93.498  100.650 1.00 17.73  ? 226 VAL S O     1 
ATOM   8324 C CB    . VAL E 5 264 ? 139.802 90.527  100.806 1.00 24.98  ? 226 VAL S CB    1 
ATOM   8325 C CG1   . VAL E 5 264 ? 138.906 90.133  101.966 1.00 25.47  ? 226 VAL S CG1   1 
ATOM   8326 C CG2   . VAL E 5 264 ? 140.472 89.304  100.203 1.00 24.63  ? 226 VAL S CG2   1 
ATOM   8327 N N     . TYR E 5 265 ? 136.969 92.389  100.479 1.00 16.00  ? 227 TYR S N     1 
ATOM   8328 C CA    . TYR E 5 265 ? 136.153 93.483  100.986 1.00 11.39  ? 227 TYR S CA    1 
ATOM   8329 C C     . TYR E 5 265 ? 135.785 93.216  102.439 1.00 17.07  ? 227 TYR S C     1 
ATOM   8330 O O     . TYR E 5 265 ? 135.237 92.157  102.762 1.00 25.57  ? 227 TYR S O     1 
ATOM   8331 C CB    . TYR E 5 265 ? 134.893 93.658  100.137 1.00 17.82  ? 227 TYR S CB    1 
ATOM   8332 C CG    . TYR E 5 265 ? 135.174 94.214  98.760  1.00 23.65  ? 227 TYR S CG    1 
ATOM   8333 C CD1   . TYR E 5 265 ? 135.707 93.410  97.761  1.00 23.63  ? 227 TYR S CD1   1 
ATOM   8334 C CD2   . TYR E 5 265 ? 134.916 95.543  98.461  1.00 20.88  ? 227 TYR S CD2   1 
ATOM   8335 C CE1   . TYR E 5 265 ? 135.970 93.913  96.505  1.00 24.26  ? 227 TYR S CE1   1 
ATOM   8336 C CE2   . TYR E 5 265 ? 135.175 96.055  97.205  1.00 20.38  ? 227 TYR S CE2   1 
ATOM   8337 C CZ    . TYR E 5 265 ? 135.702 95.235  96.231  1.00 22.93  ? 227 TYR S CZ    1 
ATOM   8338 O OH    . TYR E 5 265 ? 135.963 95.741  94.979  1.00 31.72  ? 227 TYR S OH    1 
ATOM   8339 N N     . TYR E 5 266 ? 136.089 94.176  103.306 1.00 12.43  ? 228 TYR S N     1 
ATOM   8340 C CA    . TYR E 5 266 ? 135.871 94.050  104.739 1.00 11.66  ? 228 TYR S CA    1 
ATOM   8341 C C     . TYR E 5 266 ? 134.806 95.034  105.197 1.00 14.12  ? 228 TYR S C     1 
ATOM   8342 O O     . TYR E 5 266 ? 134.767 96.182  104.744 1.00 19.37  ? 228 TYR S O     1 
ATOM   8343 C CB    . TYR E 5 266 ? 137.163 94.299  105.523 1.00 10.99  ? 228 TYR S CB    1 
ATOM   8344 C CG    . TYR E 5 266 ? 138.257 93.293  105.259 1.00 10.31  ? 228 TYR S CG    1 
ATOM   8345 C CD1   . TYR E 5 266 ? 138.271 92.068  105.910 1.00 8.23   ? 228 TYR S CD1   1 
ATOM   8346 C CD2   . TYR E 5 266 ? 139.283 93.573  104.368 1.00 10.57  ? 228 TYR S CD2   1 
ATOM   8347 C CE1   . TYR E 5 266 ? 139.271 91.147  105.676 1.00 11.20  ? 228 TYR S CE1   1 
ATOM   8348 C CE2   . TYR E 5 266 ? 140.288 92.658  104.128 1.00 16.47  ? 228 TYR S CE2   1 
ATOM   8349 C CZ    . TYR E 5 266 ? 140.277 91.448  104.786 1.00 15.35  ? 228 TYR S CZ    1 
ATOM   8350 O OH    . TYR E 5 266 ? 141.276 90.532  104.549 1.00 21.83  ? 228 TYR S OH    1 
ATOM   8351 N N     . CYS E 5 267 ? 133.944 94.574  106.098 1.00 10.91  ? 229 CYS S N     1 
ATOM   8352 C CA    . CYS E 5 267 ? 132.949 95.414  106.749 1.00 0.00   ? 229 CYS S CA    1 
ATOM   8353 C C     . CYS E 5 267 ? 133.338 95.595  108.209 1.00 6.88   ? 229 CYS S C     1 
ATOM   8354 O O     . CYS E 5 267 ? 133.652 94.620  108.899 1.00 19.56  ? 229 CYS S O     1 
ATOM   8355 C CB    . CYS E 5 267 ? 131.550 94.803  106.635 1.00 4.16   ? 229 CYS S CB    1 
ATOM   8356 S SG    . CYS E 5 267 ? 131.373 93.164  107.377 1.00 33.86  ? 229 CYS S SG    1 
ATOM   8357 N N     . MET E 5 268 ? 133.330 96.841  108.670 1.00 2.10   ? 230 MET S N     1 
ATOM   8358 C CA    . MET E 5 268 ? 133.706 97.179  110.033 1.00 3.59   ? 230 MET S CA    1 
ATOM   8359 C C     . MET E 5 268 ? 132.590 97.985  110.678 1.00 6.15   ? 230 MET S C     1 
ATOM   8360 O O     . MET E 5 268 ? 131.962 98.823  110.027 1.00 8.83   ? 230 MET S O     1 
ATOM   8361 C CB    . MET E 5 268 ? 135.018 97.974  110.066 1.00 3.96   ? 230 MET S CB    1 
ATOM   8362 C CG    . MET E 5 268 ? 135.571 98.216  111.463 1.00 5.06   ? 230 MET S CG    1 
ATOM   8363 S SD    . MET E 5 268 ? 136.652 99.655  111.548 1.00 20.62  ? 230 MET S SD    1 
ATOM   8364 C CE    . MET E 5 268 ? 135.459 100.986 111.496 1.00 0.00   ? 230 MET S CE    1 
ATOM   8365 N N     . GLN E 5 269 ? 132.341 97.722  111.955 1.00 4.30   ? 231 GLN S N     1 
ATOM   8366 C CA    . GLN E 5 269 ? 131.346 98.460  112.717 1.00 0.57   ? 231 GLN S CA    1 
ATOM   8367 C C     . GLN E 5 269 ? 132.036 99.506  113.581 1.00 12.79  ? 231 GLN S C     1 
ATOM   8368 O O     . GLN E 5 269 ? 133.153 99.293  114.061 1.00 13.83  ? 231 GLN S O     1 
ATOM   8369 C CB    . GLN E 5 269 ? 130.511 97.520  113.590 1.00 0.00   ? 231 GLN S CB    1 
ATOM   8370 C CG    . GLN E 5 269 ? 131.293 96.804  114.679 1.00 7.79   ? 231 GLN S CG    1 
ATOM   8371 C CD    . GLN E 5 269 ? 131.232 97.524  116.010 1.00 9.88   ? 231 GLN S CD    1 
ATOM   8372 O OE1   . GLN E 5 269 ? 130.428 98.436  116.197 1.00 23.35  ? 231 GLN S OE1   1 
ATOM   8373 N NE2   . GLN E 5 269 ? 132.086 97.121  116.942 1.00 0.00   ? 231 GLN S NE2   1 
ATOM   8374 N N     . HIS E 5 270 ? 131.369 100.646 113.762 1.00 15.78  ? 232 HIS S N     1 
ATOM   8375 C CA    . HIS E 5 270 ? 131.878 101.708 114.619 1.00 4.99   ? 232 HIS S CA    1 
ATOM   8376 C C     . HIS E 5 270 ? 130.823 102.214 115.596 1.00 0.43   ? 232 HIS S C     1 
ATOM   8377 O O     . HIS E 5 270 ? 131.026 103.264 116.216 1.00 2.51   ? 232 HIS S O     1 
ATOM   8378 C CB    . HIS E 5 270 ? 132.412 102.871 113.775 1.00 1.45   ? 232 HIS S CB    1 
ATOM   8379 C CG    . HIS E 5 270 ? 133.614 103.543 114.362 1.00 4.16   ? 232 HIS S CG    1 
ATOM   8380 N ND1   . HIS E 5 270 ? 133.638 104.036 115.649 1.00 3.78   ? 232 HIS S ND1   1 
ATOM   8381 C CD2   . HIS E 5 270 ? 134.835 103.804 113.837 1.00 1.62   ? 232 HIS S CD2   1 
ATOM   8382 C CE1   . HIS E 5 270 ? 134.820 104.572 115.891 1.00 0.00   ? 232 HIS S CE1   1 
ATOM   8383 N NE2   . HIS E 5 270 ? 135.565 104.444 114.809 1.00 0.00   ? 232 HIS S NE2   1 
ATOM   8384 N N     . LEU E 5 271 ? 129.705 101.501 115.748 1.00 3.77   ? 233 LEU S N     1 
ATOM   8385 C CA    . LEU E 5 271 ? 128.665 101.935 116.674 1.00 15.91  ? 233 LEU S CA    1 
ATOM   8386 C C     . LEU E 5 271 ? 129.050 101.624 118.115 1.00 14.17  ? 233 LEU S C     1 
ATOM   8387 O O     . LEU E 5 271 ? 129.262 102.533 118.924 1.00 8.69   ? 233 LEU S O     1 
ATOM   8388 C CB    . LEU E 5 271 ? 127.337 101.264 116.322 1.00 11.16  ? 233 LEU S CB    1 
ATOM   8389 C CG    . LEU E 5 271 ? 126.203 101.540 117.306 1.00 7.62   ? 233 LEU S CG    1 
ATOM   8390 C CD1   . LEU E 5 271 ? 125.512 102.844 116.961 1.00 15.42  ? 233 LEU S CD1   1 
ATOM   8391 C CD2   . LEU E 5 271 ? 125.217 100.388 117.328 1.00 13.05  ? 233 LEU S CD2   1 
ATOM   8392 N N     . GLU E 5 272 ? 129.153 100.341 118.449 1.00 22.45  ? 234 GLU S N     1 
ATOM   8393 C CA    . GLU E 5 272 ? 129.748 99.929  119.709 1.00 15.52  ? 234 GLU S CA    1 
ATOM   8394 C C     . GLU E 5 272 ? 131.256 99.941  119.546 1.00 11.57  ? 234 GLU S C     1 
ATOM   8395 O O     . GLU E 5 272 ? 131.786 99.461  118.539 1.00 11.72  ? 234 GLU S O     1 
ATOM   8396 C CB    . GLU E 5 272 ? 129.270 98.540  120.134 1.00 9.11   ? 234 GLU S CB    1 
ATOM   8397 C CG    . GLU E 5 272 ? 127.963 98.544  120.906 1.00 15.09  ? 234 GLU S CG    1 
ATOM   8398 C CD    . GLU E 5 272 ? 127.715 97.237  121.630 1.00 30.91  ? 234 GLU S CD    1 
ATOM   8399 O OE1   . GLU E 5 272 ? 128.405 96.243  121.319 1.00 33.28  ? 234 GLU S OE1   1 
ATOM   8400 O OE2   . GLU E 5 272 ? 126.835 97.203  122.516 1.00 26.49  ? 234 GLU S OE2   1 
ATOM   8401 N N     . TYR E 5 273 ? 131.943 100.499 120.536 1.00 7.45   ? 235 TYR S N     1 
ATOM   8402 C CA    . TYR E 5 273 ? 133.348 100.837 120.340 1.00 17.69  ? 235 TYR S CA    1 
ATOM   8403 C C     . TYR E 5 273 ? 134.250 99.662  119.969 1.00 19.21  ? 235 TYR S C     1 
ATOM   8404 O O     . TYR E 5 273 ? 135.128 99.856  119.111 1.00 38.15  ? 235 TYR S O     1 
ATOM   8405 C CB    . TYR E 5 273 ? 133.912 101.547 121.571 1.00 13.07  ? 235 TYR S CB    1 
ATOM   8406 C CG    . TYR E 5 273 ? 135.351 101.874 121.319 1.00 11.50  ? 235 TYR S CG    1 
ATOM   8407 C CD1   . TYR E 5 273 ? 135.703 102.972 120.548 1.00 8.56   ? 235 TYR S CD1   1 
ATOM   8408 C CD2   . TYR E 5 273 ? 136.354 101.039 121.774 1.00 16.03  ? 235 TYR S CD2   1 
ATOM   8409 C CE1   . TYR E 5 273 ? 137.016 103.252 120.280 1.00 3.91   ? 235 TYR S CE1   1 
ATOM   8410 C CE2   . TYR E 5 273 ? 137.654 101.302 121.503 1.00 27.08  ? 235 TYR S CE2   1 
ATOM   8411 C CZ    . TYR E 5 273 ? 137.988 102.412 120.765 1.00 30.41  ? 235 TYR S CZ    1 
ATOM   8412 O OH    . TYR E 5 273 ? 139.308 102.667 120.512 1.00 35.18  ? 235 TYR S OH    1 
ATOM   8413 N N     . PRO E 5 274 ? 134.132 98.456  120.557 1.00 13.18  ? 236 PRO S N     1 
ATOM   8414 C CA    . PRO E 5 274 ? 135.120 97.413  120.238 1.00 7.52   ? 236 PRO S CA    1 
ATOM   8415 C C     . PRO E 5 274 ? 135.045 96.985  118.781 1.00 15.19  ? 236 PRO S C     1 
ATOM   8416 O O     . PRO E 5 274 ? 134.460 95.949  118.449 1.00 24.64  ? 236 PRO S O     1 
ATOM   8417 C CB    . PRO E 5 274 ? 134.750 96.265  121.185 1.00 18.50  ? 236 PRO S CB    1 
ATOM   8418 C CG    . PRO E 5 274 ? 134.023 96.915  122.301 1.00 17.31  ? 236 PRO S CG    1 
ATOM   8419 C CD    . PRO E 5 274 ? 133.275 98.057  121.689 1.00 19.91  ? 236 PRO S CD    1 
ATOM   8420 N N     . LEU E 5 275 ? 135.633 97.815  117.916 1.00 14.81  ? 237 LEU S N     1 
ATOM   8421 C CA    . LEU E 5 275 ? 135.548 97.671  116.466 1.00 9.54   ? 237 LEU S CA    1 
ATOM   8422 C C     . LEU E 5 275 ? 135.841 96.247  116.022 1.00 5.42   ? 237 LEU S C     1 
ATOM   8423 O O     . LEU E 5 275 ? 136.905 95.697  116.320 1.00 10.25  ? 237 LEU S O     1 
ATOM   8424 C CB    . LEU E 5 275 ? 136.530 98.638  115.797 1.00 2.57   ? 237 LEU S CB    1 
ATOM   8425 C CG    . LEU E 5 275 ? 136.538 100.099 116.253 1.00 0.00   ? 237 LEU S CG    1 
ATOM   8426 C CD1   . LEU E 5 275 ? 137.588 100.886 115.494 1.00 0.00   ? 237 LEU S CD1   1 
ATOM   8427 C CD2   . LEU E 5 275 ? 135.172 100.733 116.075 1.00 2.32   ? 237 LEU S CD2   1 
ATOM   8428 N N     . THR E 5 276 ? 134.892 95.656  115.304 1.00 0.88   ? 238 THR S N     1 
ATOM   8429 C CA    . THR E 5 276 ? 135.029 94.310  114.776 1.00 7.37   ? 238 THR S CA    1 
ATOM   8430 C C     . THR E 5 276 ? 134.883 94.337  113.262 1.00 0.43   ? 238 THR S C     1 
ATOM   8431 O O     . THR E 5 276 ? 134.101 95.116  112.709 1.00 4.75   ? 238 THR S O     1 
ATOM   8432 C CB    . THR E 5 276 ? 133.990 93.360  115.384 1.00 10.94  ? 238 THR S CB    1 
ATOM   8433 O OG1   . THR E 5 276 ? 132.706 93.994  115.395 1.00 11.35  ? 238 THR S OG1   1 
ATOM   8434 C CG2   . THR E 5 276 ? 134.377 92.992  116.808 1.00 9.35   ? 238 THR S CG2   1 
ATOM   8435 N N     . PHE E 5 277 ? 135.648 93.479  112.597 1.00 4.52   ? 239 PHE S N     1 
ATOM   8436 C CA    . PHE E 5 277 ? 135.656 93.385  111.147 1.00 10.80  ? 239 PHE S CA    1 
ATOM   8437 C C     . PHE E 5 277 ? 134.942 92.117  110.700 1.00 14.69  ? 239 PHE S C     1 
ATOM   8438 O O     . PHE E 5 277 ? 134.842 91.142  111.450 1.00 16.83  ? 239 PHE S O     1 
ATOM   8439 C CB    . PHE E 5 277 ? 137.087 93.387  110.600 1.00 6.03   ? 239 PHE S CB    1 
ATOM   8440 C CG    . PHE E 5 277 ? 137.760 94.727  110.659 1.00 7.13   ? 239 PHE S CG    1 
ATOM   8441 C CD1   . PHE E 5 277 ? 138.349 95.170  111.830 1.00 7.46   ? 239 PHE S CD1   1 
ATOM   8442 C CD2   . PHE E 5 277 ? 137.812 95.539  109.540 1.00 5.52   ? 239 PHE S CD2   1 
ATOM   8443 C CE1   . PHE E 5 277 ? 138.972 96.401  111.886 1.00 0.00   ? 239 PHE S CE1   1 
ATOM   8444 C CE2   . PHE E 5 277 ? 138.433 96.770  109.589 1.00 1.14   ? 239 PHE S CE2   1 
ATOM   8445 C CZ    . PHE E 5 277 ? 139.014 97.201  110.764 1.00 0.00   ? 239 PHE S CZ    1 
ATOM   8446 N N     . GLY E 5 278 ? 134.443 92.141  109.471 1.00 10.86  ? 240 GLY S N     1 
ATOM   8447 C CA    . GLY E 5 278 ? 133.864 90.955  108.882 1.00 8.24   ? 240 GLY S CA    1 
ATOM   8448 C C     . GLY E 5 278 ? 134.928 89.965  108.452 1.00 14.06  ? 240 GLY S C     1 
ATOM   8449 O O     . GLY E 5 278 ? 136.127 90.248  108.436 1.00 19.26  ? 240 GLY S O     1 
ATOM   8450 N N     . ALA E 5 279 ? 134.469 88.763  108.097 1.00 20.59  ? 241 ALA S N     1 
ATOM   8451 C CA    . ALA E 5 279 ? 135.394 87.719  107.666 1.00 20.94  ? 241 ALA S CA    1 
ATOM   8452 C C     . ALA E 5 279 ? 136.120 88.103  106.384 1.00 18.31  ? 241 ALA S C     1 
ATOM   8453 O O     . ALA E 5 279 ? 137.225 87.612  106.126 1.00 19.59  ? 241 ALA S O     1 
ATOM   8454 C CB    . ALA E 5 279 ? 134.647 86.399  107.479 1.00 23.95  ? 241 ALA S CB    1 
ATOM   8455 N N     . GLY E 5 280 ? 135.524 88.973  105.574 1.00 15.62  ? 242 GLY S N     1 
ATOM   8456 C CA    . GLY E 5 280 ? 136.140 89.395  104.333 1.00 12.17  ? 242 GLY S CA    1 
ATOM   8457 C C     . GLY E 5 280 ? 135.602 88.655  103.127 1.00 19.74  ? 242 GLY S C     1 
ATOM   8458 O O     . GLY E 5 280 ? 135.621 87.421  103.090 1.00 31.42  ? 242 GLY S O     1 
ATOM   8459 N N     . THR E 5 281 ? 135.118 89.396  102.135 1.00 20.51  ? 243 THR S N     1 
ATOM   8460 C CA    . THR E 5 281 ? 134.576 88.825  100.907 1.00 21.78  ? 243 THR S CA    1 
ATOM   8461 C C     . THR E 5 281 ? 135.597 89.031  99.796  1.00 23.10  ? 243 THR S C     1 
ATOM   8462 O O     . THR E 5 281 ? 135.809 90.159  99.340  1.00 28.24  ? 243 THR S O     1 
ATOM   8463 C CB    . THR E 5 281 ? 133.237 89.465  100.547 1.00 26.15  ? 243 THR S CB    1 
ATOM   8464 O OG1   . THR E 5 281 ? 132.297 89.239  101.605 1.00 29.19  ? 243 THR S OG1   1 
ATOM   8465 C CG2   . THR E 5 281 ? 132.693 88.868  99.260  1.00 28.39  ? 243 THR S CG2   1 
ATOM   8466 N N     . LYS E 5 282 ? 136.224 87.942  99.363  1.00 34.26  ? 244 LYS S N     1 
ATOM   8467 C CA    . LYS E 5 282 ? 137.248 88.013  98.331  1.00 33.81  ? 244 LYS S CA    1 
ATOM   8468 C C     . LYS E 5 282 ? 136.618 87.977  96.945  1.00 33.77  ? 244 LYS S C     1 
ATOM   8469 O O     . LYS E 5 282 ? 135.698 87.198  96.683  1.00 35.51  ? 244 LYS S O     1 
ATOM   8470 C CB    . LYS E 5 282 ? 138.239 86.860  98.485  1.00 33.50  ? 244 LYS S CB    1 
ATOM   8471 C CG    . LYS E 5 282 ? 139.377 86.875  97.480  1.00 33.83  ? 244 LYS S CG    1 
ATOM   8472 C CD    . LYS E 5 282 ? 140.298 85.683  97.674  1.00 38.77  ? 244 LYS S CD    1 
ATOM   8473 C CE    . LYS E 5 282 ? 141.377 85.637  96.606  1.00 35.39  ? 244 LYS S CE    1 
ATOM   8474 N NZ    . LYS E 5 282 ? 142.252 84.441  96.753  1.00 31.31  ? 244 LYS S NZ    1 
ATOM   8475 N N     . LEU E 5 283 ? 137.120 88.831  96.058  1.00 36.47  ? 245 LEU S N     1 
ATOM   8476 C CA    . LEU E 5 283 ? 136.692 88.863  94.666  1.00 34.87  ? 245 LEU S CA    1 
ATOM   8477 C C     . LEU E 5 283 ? 137.776 88.241  93.796  1.00 39.54  ? 245 LEU S C     1 
ATOM   8478 O O     . LEU E 5 283 ? 138.953 88.597  93.915  1.00 40.97  ? 245 LEU S O     1 
ATOM   8479 C CB    . LEU E 5 283 ? 136.402 90.295  94.214  1.00 33.74  ? 245 LEU S CB    1 
ATOM   8480 C CG    . LEU E 5 283 ? 134.932 90.717  94.195  1.00 37.92  ? 245 LEU S CG    1 
ATOM   8481 C CD1   . LEU E 5 283 ? 134.319 90.618  95.583  1.00 37.14  ? 245 LEU S CD1   1 
ATOM   8482 C CD2   . LEU E 5 283 ? 134.784 92.123  93.638  1.00 36.94  ? 245 LEU S CD2   1 
ATOM   8483 N N     . GLU E 5 284 ? 137.378 87.314  92.931  1.00 46.49  ? 246 GLU S N     1 
ATOM   8484 C CA    . GLU E 5 284 ? 138.304 86.598  92.069  1.00 45.75  ? 246 GLU S CA    1 
ATOM   8485 C C     . GLU E 5 284 ? 137.955 86.842  90.607  1.00 47.88  ? 246 GLU S C     1 
ATOM   8486 O O     . GLU E 5 284 ? 136.806 87.131  90.260  1.00 49.96  ? 246 GLU S O     1 
ATOM   8487 C CB    . GLU E 5 284 ? 138.288 85.092  92.367  1.00 46.19  ? 246 GLU S CB    1 
ATOM   8488 N N     . LEU E 5 285 ? 138.971 86.720  89.756  1.00 47.55  ? 247 LEU S N     1 
ATOM   8489 C CA    . LEU E 5 285 ? 138.833 86.915  88.313  1.00 48.46  ? 247 LEU S CA    1 
ATOM   8490 C C     . LEU E 5 285 ? 138.254 88.288  87.981  1.00 49.44  ? 247 LEU S C     1 
ATOM   8491 O O     . LEU E 5 285 ? 138.908 89.311  88.179  1.00 47.95  ? 247 LEU S O     1 
ATOM   8492 C CB    . LEU E 5 285 ? 137.960 85.815  87.702  1.00 45.81  ? 247 LEU S CB    1 
HETATM 8493 C "C1'" . UGA F 6 .   ? 122.405 130.676 172.110 1.00 63.50  ? 401 UGA R "C1'" 1 
HETATM 8494 C "C2'" . UGA F 6 .   ? 122.332 130.789 170.578 1.00 67.07  ? 401 UGA R "C2'" 1 
HETATM 8495 O "O2'" . UGA F 6 .   ? 122.768 132.089 170.149 1.00 70.12  ? 401 UGA R "O2'" 1 
HETATM 8496 C "C3'" . UGA F 6 .   ? 120.934 130.508 170.031 1.00 71.23  ? 401 UGA R "C3'" 1 
HETATM 8497 O "O3'" . UGA F 6 .   ? 120.914 129.219 169.421 1.00 71.04  ? 401 UGA R "O3'" 1 
HETATM 8498 C "C4'" . UGA F 6 .   ? 119.905 130.576 171.143 1.00 71.66  ? 401 UGA R "C4'" 1 
HETATM 8499 O "O4'" . UGA F 6 .   ? 118.602 130.735 170.578 1.00 74.62  ? 401 UGA R "O4'" 1 
HETATM 8500 C "C5'" . UGA F 6 .   ? 120.274 131.766 172.017 1.00 72.12  ? 401 UGA R "C5'" 1 
HETATM 8501 O "O5'" . UGA F 6 .   ? 121.404 131.419 172.807 1.00 66.62  ? 401 UGA R "O5'" 1 
HETATM 8502 C "C6'" . UGA F 6 .   ? 119.151 132.187 172.918 1.00 78.18  ? 401 UGA R "C6'" 1 
HETATM 8503 O "O'P" . UGA F 6 .   ? 118.228 131.383 173.164 1.00 75.28  ? 401 UGA R "O'P" 1 
HETATM 8504 O "O'Q" . UGA F 6 .   ? 119.198 133.343 173.390 1.00 74.77  ? 401 UGA R "O'Q" 1 
HETATM 8505 P PB    . UGA F 6 .   ? 124.824 130.116 172.842 1.00 70.80  ? 401 UGA R PB    1 
HETATM 8506 O O1B   . UGA F 6 .   ? 124.231 128.986 173.641 1.00 71.77  ? 401 UGA R O1B   1 
HETATM 8507 O O2B   . UGA F 6 .   ? 126.056 130.831 173.339 1.00 69.01  ? 401 UGA R O2B   1 
HETATM 8508 O O3B   . UGA F 6 .   ? 123.662 131.175 172.556 1.00 67.15  ? 401 UGA R O3B   1 
HETATM 8509 O O3A   . UGA F 6 .   ? 125.063 129.581 171.352 1.00 57.34  ? 401 UGA R O3A   1 
HETATM 8510 P PA    . UGA F 6 .   ? 126.493 129.714 170.658 1.00 60.62  ? 401 UGA R PA    1 
HETATM 8511 O O1A   . UGA F 6 .   ? 127.457 128.959 171.543 1.00 68.59  ? 401 UGA R O1A   1 
HETATM 8512 O O2A   . UGA F 6 .   ? 126.777 131.156 170.288 1.00 70.85  ? 401 UGA R O2A   1 
HETATM 8513 O O5D   . UGA F 6 .   ? 126.255 128.896 169.300 1.00 61.22  ? 401 UGA R O5D   1 
HETATM 8514 C C5D   . UGA F 6 .   ? 124.972 128.364 168.976 1.00 59.62  ? 401 UGA R C5D   1 
HETATM 8515 C C4D   . UGA F 6 .   ? 125.115 126.994 168.328 1.00 64.64  ? 401 UGA R C4D   1 
HETATM 8516 O O4D   . UGA F 6 .   ? 125.985 127.047 167.192 1.00 62.74  ? 401 UGA R O4D   1 
HETATM 8517 C C3D   . UGA F 6 .   ? 125.714 126.015 169.311 1.00 64.37  ? 401 UGA R C3D   1 
HETATM 8518 O O3D   . UGA F 6 .   ? 125.074 124.745 169.215 1.00 72.11  ? 401 UGA R O3D   1 
HETATM 8519 C C2D   . UGA F 6 .   ? 127.157 125.913 168.891 1.00 62.47  ? 401 UGA R C2D   1 
HETATM 8520 O O2D   . UGA F 6 .   ? 127.725 124.626 169.197 1.00 70.29  ? 401 UGA R O2D   1 
HETATM 8521 C C1D   . UGA F 6 .   ? 127.137 126.229 167.403 1.00 58.62  ? 401 UGA R C1D   1 
HETATM 8522 N N1    . UGA F 6 .   ? 128.353 126.944 167.019 1.00 59.87  ? 401 UGA R N1    1 
HETATM 8523 C C6    . UGA F 6 .   ? 128.815 127.938 167.772 1.00 64.14  ? 401 UGA R C6    1 
HETATM 8524 C C2    . UGA F 6 .   ? 129.047 126.583 165.851 1.00 64.00  ? 401 UGA R C2    1 
HETATM 8525 O O2    . UGA F 6 .   ? 128.621 125.651 165.137 1.00 72.74  ? 401 UGA R O2    1 
HETATM 8526 N N3    . UGA F 6 .   ? 130.160 127.232 165.495 1.00 63.16  ? 401 UGA R N3    1 
HETATM 8527 C C4    . UGA F 6 .   ? 130.639 128.231 166.239 1.00 62.42  ? 401 UGA R C4    1 
HETATM 8528 O O4    . UGA F 6 .   ? 131.687 128.829 165.895 1.00 62.35  ? 401 UGA R O4    1 
HETATM 8529 C C5    . UGA F 6 .   ? 129.970 128.604 167.395 1.00 59.66  ? 401 UGA R C5    1 
# 
